id name category provided_by subsets iri xrefs synonym description CHEBI:26547 rhamnoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26547 CHEBI:26548 rhamnosylglucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26548 CHEBI:26543 rhamnogalacturonan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26543 CHEBI:26544 rhamnonate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26544 CHEBI:26545 rhamnonolactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26545 CHEBI:26546 rhamnose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26546 CHEBI:51507 benzil biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_51507 CHEBI:51509 (R)-benzoin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_51509 CHEBI:26558 ribonucleoside monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26558 CHEBI:26554 ribitol phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26554 CHEBI:26556 1-ribosylimidazolecarboxamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26556 GO:0099593 endocytosed synaptic vesicle to endosome fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099593 Fusion of an endocytosed synaptic vesicle with an endosome. CHEBI:26523 reactive oxygen species biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26523 GO:0099592 endocytosed synaptic vesicle processing via endosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099592 synaptic vesicle processing via endosome involved in synaptic vesicle recycling The process in which endocytosed synaptic vesicles fuse to the presynaptic endosome followed by sorting of synaptic vesicle components and budding of new synaptic vesicles. GO:0099590 neurotransmitter receptor internalization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099590 A receptor-mediated endocytosis process that results in the internalization of a neurotransmitter receptor. CHEBI:26536 retinoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26536 CHEBI:75504 pyranoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75504 CHEBI:26537 retinoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26537 CHEBI:75507 3-dehydropyranoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75507 CHEBI:26533 reticuline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26533 CHEBI:26534 retinals biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26534 CHEBI:26507 dihydroxyquinoline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26507 CHEBI:26508 quinoline N-oxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26508 CHEBI:26509 quinoline alkaloid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26509 CHEBI:75525 D-galactopyranuronate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75525 CHEBI:26515 quinolizidine alkaloid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26515 CHEBI:26516 quinolizidines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26516 CHEBI:75524 2,3-diacyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75524 CHEBI:75529 1-lauroyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75529 CHEBI:26512 quinolinemonocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26512 CHEBI:26513 quinolines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26513 CHEBI:75528 3-lauroyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75528 CHEBI:26519 radical biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26519 CHEBI:75522 beta-L-galactose 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75522 CHEBI:75536 1-myristoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75536 CHEBI:75537 3-myristoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75537 CHEBI:75539 1-monolauroylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75539 CHEBI:75533 3-lauroyl-2-oleoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75533 CHEBI:75547 1-monodecanoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75547 CHEBI:75545 2-keto-3-deoxy-L-galactonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75545 CHEBI:75546 2-oleoyl-3-palmitoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75546 CHEBI:75540 2-oleoyl-3-myristoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75540 CHEBI:75542 1-hexadecanoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75542 GO:0051599 response to hydrostatic pressure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051599 response to biomechanical stress|response to static fluid pressure Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it. GO:0002621 positive regulation of non-professional antigen presenting cell antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002621 up regulation of non-professional antigen presenting cell antigen processing and presentation|upregulation of non-professional antigen presenting cell antigen processing and presentation|stimulation of non-professional antigen presenting cell antigen processing and presentation|up-regulation of non-professional antigen presenting cell antigen processing and presentation|activation of non-professional antigen presenting cell antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation. GO:0099533 positive regulation of presynaptic cytosolic calcium concentration biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099533 Any process that increases the concentration of calcium ions in the presynaptic cytosol. GO:0099534 calcium ion binding involved in regulation of presynaptic cytosolic calcium ion concentration biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099534 presynaptic calcium ion buffering|regulation of presynaptic cytosolic calcium ion concentration by calcium ion buffering|calcium ion binding involved in regulation of presynaptic cytosolic calcium levels The directed change of presynaptic cytosolic free calcium ion concentration in the cytosol via the reversible binding of calcium ions to calcium-binding proteins in the cytosol thereby modulating the spatial and temporal dynamics of changes in presynaptic cytosolic calcium concentrations. GO:0002622 regulation of B cell antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002622 regulation of B-cell antigen processing and presentation|regulation of B-lymphocyte antigen processing and presentation|regulation of B lymphocyte antigen processing and presentation Any process that modulates the frequency, rate, or extent of B cell antigen processing and presentation. GO:0002623 negative regulation of B cell antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002623 negative regulation of B-cell antigen processing and presentation|negative regulation of B-lymphocyte antigen processing and presentation|down-regulation of B cell antigen processing and presentation|negative regulation of B lymphocyte antigen processing and presentation|downregulation of B cell antigen processing and presentation|down regulation of B cell antigen processing and presentation|inhibition of B cell antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell antigen processing and presentation. GO:0099531 presynaptic process involved in chemical synaptic transmission biolink:BiologicalProcess go-plus goslim_synapse|gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0099531 The pathway leading to secretion of a neurotransmitter from the presynapse as part of synaptic transmission. GO:0051597 response to methylmercury biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051597 response to MeHg+|response to CH3-Hg+ Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylmercury stimulus. GO:0051598 meiotic recombination checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051598 pachytene checkpoint A checkpoint that acts during late prophase I (pachytene) and prevents segregation of homologous chromosomes until recombination is completed, ensuring proper distribution of the genetic material to the gametes. GO:0002624 positive regulation of B cell antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002624 upregulation of B cell antigen processing and presentation|positive regulation of B-cell antigen processing and presentation|stimulation of B cell antigen processing and presentation|up-regulation of B cell antigen processing and presentation|activation of B cell antigen processing and presentation|positive regulation of B-lymphocyte antigen processing and presentation|up regulation of B cell antigen processing and presentation|positive regulation of B lymphocyte antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of B cell antigen processing and presentation. GO:0099532 synaptic vesicle endosomal processing biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099532 synaptic vesicle processing via endosome The process in which synaptic vesicles fuse to the presynaptic endosome followed by sorting of synaptic vesicle components and budding of new synaptic vesicles. NCBITaxon:4896 Schizosaccharomyces pombe organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_4896 fission yeast|Schizosaccharomyces malidevorans GO:0099530 G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential A G protein-coupled receptor activity occurring in the postsynaptic membrane that is part of a GPCR signaling pathway that positively regulates ion channel activity in the postsynaptic membrane. NCBITaxon:4894 Schizosaccharomycetaceae organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_4894 fission yeasts|Schizosaccharomycetoideae GO:0002620 negative regulation of non-professional antigen presenting cell antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002620 downregulation of non-professional antigen presenting cell antigen processing and presentation|down regulation of non-professional antigen presenting cell antigen processing and presentation|inhibition of non-professional antigen presenting cell antigen processing and presentation|down-regulation of non-professional antigen presenting cell antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation. NCBITaxon:4895 Schizosaccharomyces organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_4895 GO:0002629 negative regulation of proteolysis associated with antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002629 down regulation of proteolysis associated with antigen processing and presentation|downregulation of proteolysis associated with antigen processing and presentation|down-regulation of proteolysis associated with antigen processing and presentation|inhibition of proteolysis associated with antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of proteolysis associated with antigen processing and presentation. GO:0051591 response to cAMP biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051591 response to 3',5'-cAMP|response to adenosine 3',5'-cyclophosphate|response to cyclic AMP|response to 3',5' cAMP Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus. GO:0051592 response to calcium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051592 response to Ca2+ ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus. GO:0099539 neuropeptide secretion from presynapse biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099539 neuropeptide secretion from presynapse via dense core granule exocytosis The secretion of neuropeptides contained within a dense core vesicle by fusion of the granule with the presynaptic membrane, stimulated by a rise in cytosolic calcium ion concentration. GO:0051590 positive regulation of neurotransmitter transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051590 up regulation of neurotransmitter transport|upregulation of neurotransmitter transport|stimulation of neurotransmitter transport|up-regulation of neurotransmitter transport|activation of neurotransmitter transport Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:51586 benzoins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51586 GO:0002625 regulation of T cell antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002625 regulation of T-cell antigen processing and presentation|regulation of T-lymphocyte antigen processing and presentation|regulation of T lymphocyte antigen processing and presentation Any process that modulates the frequency, rate, or extent of T cell antigen processing and presentation. GO:0051595 response to methylglyoxal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051595 response to pyruvaldehyde Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. Methylglyoxal is a 2-oxoaldehyde derived from propanal. GO:0099537 trans-synaptic signaling biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099537 Cell-cell signaling in either direction across the synaptic cleft. GO:0051596 methylglyoxal catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051596 MetaCyc:METHGLYUT-PWY|MetaCyc:Methylglyoxal-Detoxification methylglyoxal degradation|methylglyoxal breakdown|methylglyoxal catabolism The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid. GO:0099538 synaptic signaling via neuropeptide biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099538 Cell-cell signaling to or from a synapse, mediated by a peptide. GO:0002626 negative regulation of T cell antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002626 down-regulation of T cell antigen processing and presentation|negative regulation of T lymphocyte antigen processing and presentation|downregulation of T cell antigen processing and presentation|down regulation of T cell antigen processing and presentation|inhibition of T cell antigen processing and presentation|negative regulation of T-cell antigen processing and presentation|negative regulation of T-lymphocyte antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell antigen processing and presentation. GO:0051593 response to folic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051593 cellular response to folate|cellular response to vitamin B9 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a folic acid stimulus. GO:0002627 positive regulation of T cell antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002627 positive regulation of T-lymphocyte antigen processing and presentation|up regulation of T cell antigen processing and presentation|positive regulation of T lymphocyte antigen processing and presentation|upregulation of T cell antigen processing and presentation|stimulation of T cell antigen processing and presentation|positive regulation of T-cell antigen processing and presentation|activation of T cell antigen processing and presentation|up-regulation of T cell antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of T cell antigen processing and presentation. GO:0099535 synapse-associated extracellular matrix biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099535 extra-synaptic extracellular matrix The extracellular matrix of the perisynaptic space (the extracellular space adjacent to the synapse) and the synaptic cleft. GO:0099536 synaptic signaling biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099536 Cell-cell signaling to, from or within a synapse. GO:0002628 regulation of proteolysis associated with antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002628 Any process that modulates the frequency, rate, or extent of proteolysis associated with antigen processing and presentation. GO:0051594 detection of glucose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051594 glucose sensing|glucose detection|glucose perception The series of events in which a glucose stimulus is received by a cell and converted into a molecular signal. GO:0099544 perisynaptic space biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099544 extrasynaptic space The extracellular region immediately adjacent to to a synapse. GO:0002632 negative regulation of granuloma formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002632 down regulation of granuloma formation|downregulation of granuloma formation|down-regulation of granuloma formation|inhibition of granuloma formation Any process that stops, prevents, or reduces the frequency, rate, or extent of granuloma formation. GO:0099545 trans-synaptic signaling by trans-synaptic complex biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099545 Cell-cell signaling between presynapse and postsynapse mediated by a trans-synaptic protein complex. GO:0002633 positive regulation of granuloma formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002633 upregulation of granuloma formation|up regulation of granuloma formation|activation of granuloma formation|stimulation of granuloma formation|up-regulation of granuloma formation Any process that activates or increases the frequency, rate, or extent of granuloma formation. GO:0002634 regulation of germinal center formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002634 Any process that modulates the frequency, rate, or extent of germinal center formation. GO:0099542 trans-synaptic signaling by endocannabinoid biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099542 Cell-cell signaling in either direction across the synaptic cleft, mediated by an endocannabinoid ligand. GO:0002635 negative regulation of germinal center formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002635 inhibition of germinal center formation|down regulation of germinal center formation|downregulation of germinal center formation|down-regulation of germinal center formation Any process that stops, prevents, or reduces the frequency, rate, or extent of germinal center formation. GO:0099543 trans-synaptic signaling by soluble gas biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099543 Cell-cell signaling between presynapse and postsynapse mediated by a soluble gas ligand crossing the synaptic cleft. GO:0099540 trans-synaptic signaling by neuropeptide biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099540 Cell-cell signaling between presynapse and postsynapse mediated by a peptide ligand crossing the synaptic cleft. GO:0099541 trans-synaptic signaling by lipid biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099541 Cell-cell signaling from post to pre-synapse, across the synaptic cleft, mediated by a lipid. GO:0002630 positive regulation of proteolysis associated with antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002630 up-regulation of proteolysis associated with antigen processing and presentation|upregulation of proteolysis associated with antigen processing and presentation|up regulation of proteolysis associated with antigen processing and presentation|activation of proteolysis associated with antigen processing and presentation|stimulation of proteolysis associated with antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of proteolysis associated with antigen processing and presentation. GO:0002631 regulation of granuloma formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002631 Any process that modulates the frequency, rate, or extent of granuloma formation. GO:0099548 trans-synaptic signaling by nitric oxide biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099548 Cell-cell signaling between presynapse and postsynapse mediated by nitric oxide. GO:0002636 positive regulation of germinal center formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002636 up-regulation of germinal center formation|upregulation of germinal center formation|up regulation of germinal center formation|activation of germinal center formation|stimulation of germinal center formation Any process that activates or increases the frequency, rate, or extent of germinal center formation. GO:0099549 trans-synaptic signaling by carbon monoxide biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099549 Cell-cell signaling between presynapse and postsynapse mediated by carbon monoxide. GO:0002637 regulation of immunoglobulin production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002637 regulation of immunoglobulin secretion|regulation of antibody production|regulation of immunoglobulin biosynthetic process Any process that modulates the frequency, rate, or extent of immunoglobulin production. GO:0002638 negative regulation of immunoglobulin production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002638 negative regulation of immunoglobulin secretion|down-regulation of immunoglobulin production|inhibition of immunoglobulin production|negative regulation of immunoglobulin biosynthetic process|down regulation of immunoglobulin production|downregulation of immunoglobulin production Any process that stops, prevents, or reduces the frequency, rate, or extent of immunoglobulin production. GO:0099546 protein catabolic process, modulating synaptic transmission biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099546 Any protein degradation process, occurring at a presynapse, that regulates synaptic transmission. CHEBI:51570 biotins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51570 GO:0099547 regulation of translation at synapse, modulating synaptic transmission biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099547 Any process that modulates synaptic transmission by regulating translation occurring at the synapse. GO:0002639 positive regulation of immunoglobulin production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002639 stimulation of immunoglobulin production|positive regulation of immunoglobulin secretion|positive regulation of immunoglobulin biosynthetic process|up-regulation of immunoglobulin production|upregulation of immunoglobulin production|up regulation of immunoglobulin production|activation of immunoglobulin production Any process that activates or increases the frequency, rate, or extent of immunoglobulin production. CHEBI:51571 diphenylethane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51571 CHEBI:51569 N-acyl-amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51569 GO:0099511 voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099511 Regulation of cytosolic calcium ion concentrations via the directed movement of calcium ions across the plasma-membrane into the cytosol via the action of a voltage-gated calcium ion channel. GO:0002600 positive regulation of antigen processing and presentation of lipid antigen via MHC class Ib biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002600 upregulation of antigen processing and presentation of lipid antigen via MHC class Ib|up regulation of antigen processing and presentation of lipid antigen via MHC class Ib|activation of antigen processing and presentation of lipid antigen via MHC class Ib|positive regulation of lipid antigen processing and presentation via MHC class Ib|stimulation of antigen processing and presentation of lipid antigen via MHC class Ib|up-regulation of antigen processing and presentation of lipid antigen via MHC class Ib Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib. GO:0099512 supramolecular fiber biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0099512 fibril A polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure. GO:0002601 regulation of antigen processing and presentation of polysaccharide antigen via MHC class II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002601 regulation of polysaccharide antigen processing and presentation via MHC class II Any process that modulates the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II. GO:0002602 negative regulation of antigen processing and presentation of polysaccharide antigen via MHC class II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002602 down-regulation of antigen processing and presentation of polysaccharide antigen via MHC class II|negative regulation of polysaccharide antigen processing and presentation via MHC class II|downregulation of antigen processing and presentation of polysaccharide antigen via MHC class II|down regulation of antigen processing and presentation of polysaccharide antigen via MHC class II|inhibition of antigen processing and presentation of polysaccharide antigen via MHC class II Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II. GO:0099510 calcium ion binding involved in regulation of cytosolic calcium ion concentration biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0099510 regulation of cytosolic calcium ion concentration by calcium ion buffering The directed change of cytosolic calcium ion concentration in the cytosol via the reversible binding of calcium ions to calcium-binding proteins in the cytosol thereby modulating the spatial and temporal dynamics of changes in cytosolic calcium concentrations. GO:0002607 regulation of myeloid dendritic cell antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002607 Any process that modulates the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation. GO:0099519 dense core granule cytoskeletal transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099519 dense core granule cytoskeletal transport|dense core vesicle cytoskeletal trafficking The directed movement of dense core granules along cytoskeletal fibers, such as microtubules or actin filaments. GO:0002608 negative regulation of myeloid dendritic cell antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002608 down-regulation of myeloid dendritic cell antigen processing and presentation|downregulation of myeloid dendritic cell antigen processing and presentation|down regulation of myeloid dendritic cell antigen processing and presentation|inhibition of myeloid dendritic cell antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation. GO:0002609 positive regulation of myeloid dendritic cell antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002609 stimulation of myeloid dendritic cell antigen processing and presentation|up-regulation of myeloid dendritic cell antigen processing and presentation|activation of myeloid dendritic cell antigen processing and presentation|up regulation of myeloid dendritic cell antigen processing and presentation|upregulation of myeloid dendritic cell antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation. GO:0099517 synaptic vesicle transport along microtubule biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099517 The directed movement of synaptic vesicles along microtubules within a cell, powered by molecular motors. GO:0099518 vesicle cytoskeletal trafficking biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099518 cytoskeletal fiber-based vesicle localization|vesicle cytoskeletal transport The directed movement of a vesicle along a cytoskeletal fiber such as a microtubule or and actin filament, mediated by motor proteins. GO:0002603 positive regulation of antigen processing and presentation of polysaccharide antigen via MHC class II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002603 positive regulation of polysaccharide antigen processing and presentation via MHC class II|up regulation of antigen processing and presentation of polysaccharide antigen via MHC class II|upregulation of antigen processing and presentation of polysaccharide antigen via MHC class II|stimulation of antigen processing and presentation of polysaccharide antigen via MHC class II|up-regulation of antigen processing and presentation of polysaccharide antigen via MHC class II|activation of antigen processing and presentation of polysaccharide antigen via MHC class II Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II. GO:0099515 actin filament-based transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099515 The transport of organelles or other particles from one location in the cell to another along actin filaments. GO:0002604 regulation of dendritic cell antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002604 Any process that modulates the frequency, rate, or extent of dendritic cell antigen processing and presentation. GO:0099516 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0099516 GO:0002605 negative regulation of dendritic cell antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002605 down regulation of dendritic cell antigen processing and presentation|inhibition of dendritic cell antigen processing and presentation|down-regulation of dendritic cell antigen processing and presentation|downregulation of dendritic cell antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell antigen processing and presentation. GO:0099513 polymeric cytoskeletal fiber biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0099513 A component of the cytoskeleton consisting of a homo or heteropolymeric fiber constructed from an indeterminate number of protein subunits. GO:0002606 positive regulation of dendritic cell antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002606 upregulation of dendritic cell antigen processing and presentation|stimulation of dendritic cell antigen processing and presentation|up-regulation of dendritic cell antigen processing and presentation|activation of dendritic cell antigen processing and presentation|up regulation of dendritic cell antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of dendritic cell antigen processing and presentation. GO:0099514 synaptic vesicle cytoskeletal transport biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099514 The directed movement of synaptic vesicles along cytoskeletal fibers such as microfilaments or microtubules within a cell, powered by molecular motors. GO:0002610 regulation of plasmacytoid dendritic cell antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002610 Any process that modulates the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation. GO:0099522 region of cytosol biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0099522 Any (proper) part of the cytosol of a single cell of sufficient size to still be considered cytosol. GO:0002611 negative regulation of plasmacytoid dendritic cell antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002611 downregulation of plasmacytoid dendritic cell antigen processing and presentation|down-regulation of plasmacytoid dendritic cell antigen processing and presentation|inhibition of plasmacytoid dendritic cell antigen processing and presentation|down regulation of plasmacytoid dendritic cell antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation. GO:0099523 presynaptic cytosol biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099523 The region of the cytosol consisting of all cytosol that is part of the presynapse. GO:0099520 ion antiporter activity involved in regulation of presynaptic membrane potential biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099520 ion antiporter activity involved in regulation of pre-synaptic membrane potential Any ion antiporter activity, occurring in the presynaptic membrane, that is involved in regulation of presynaptic membrane potential. GO:0002612 positive regulation of plasmacytoid dendritic cell antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002612 up regulation of plasmacytoid dendritic cell antigen processing and presentation|activation of plasmacytoid dendritic cell antigen processing and presentation|stimulation of plasmacytoid dendritic cell antigen processing and presentation|up-regulation of plasmacytoid dendritic cell antigen processing and presentation|upregulation of plasmacytoid dendritic cell antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation. GO:0099521 ATPase coupled ion transmembrane transporter activity involved in regulation of presynaptic membrane potential biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099521 ATPase-coupled ion transmembrane transporter activity involved in regulation of presynaptic membrane potential|ATPase coupled ion transmembrane transporter activity involved in regulation of pre-synaptic membrane potential Any ATPase coupled ion transmembrane transporter activity, occurring in the presynaptic membrane, that is involved in regulation of presynaptic membrane potential. GO:0002613 regulation of monocyte antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002613 Any process that modulates the frequency, rate, or extent of monocyte antigen processing and presentation. GO:0002618 positive regulation of macrophage antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002618 stimulation of macrophage antigen processing and presentation|up-regulation of macrophage antigen processing and presentation|activation of macrophage antigen processing and presentation|up regulation of macrophage antigen processing and presentation|upregulation of macrophage antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of macrophage antigen processing and presentation. NCBITaxon:4892 Saccharomycetales organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_4892 budding yeasts|Endomycetales GO:0002619 regulation of non-professional antigen presenting cell antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002619 Any process that modulates the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation. NCBITaxon:4893 Saccharomycetaceae organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_4893 NCBITaxon:4890 Ascomycota organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_4890 ascomycetes|sac fungi|ascomycetes GO:0099528 G protein-coupled neurotransmitter receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0099528 G-protein coupled neurotransmitter receptor activity Combining with a neurotransmitter and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099529 Neurotransmitter receptor activity occurring in the postsynaptic membrane that is involved in regulating postsynaptic membrane potential, either directly (ionotropic receptors) or indirectly (e.g. via GPCR activation of an ion channel). NCBITaxon:4891 Saccharomycetes organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_4891 Hemiascomycetes GO:0099526 presynapse to nucleus signaling pathway biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099526 presynaptic signaling to nucleus A series of molecular signals that conveys information from the presynapse to the nucleus via cytoskeletal transport of a protein from a presynapse to the component to the nucleus where it affects biochemical processes that occur in the nucleus (e.g DNA transcription, mRNA splicing, or DNA/histone modifications). GO:0002614 negative regulation of monocyte antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002614 downregulation of monocyte antigen processing and presentation|down regulation of monocyte antigen processing and presentation|inhibition of monocyte antigen processing and presentation|down-regulation of monocyte antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of monocyte antigen processing and presentation. GO:0002615 positive regulation of monocyte antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002615 up regulation of monocyte antigen processing and presentation|upregulation of monocyte antigen processing and presentation|stimulation of monocyte antigen processing and presentation|up-regulation of monocyte antigen processing and presentation|activation of monocyte antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of monocyte antigen processing and presentation. GO:0099527 postsynapse to nucleus signaling pathway biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099527 postsynaptic signaling to nucleus A series of molecular signals that conveys information from the postsynapse to the nucleus via cytoskeletal transport of a protein from a postsynapse to the component to the nucleus where it affects biochemical processes that occur in the nucleus (e.g DNA transcription, mRNA splicing, or DNA/histone modifications). GO:0099524 postsynaptic cytosol biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099524 The region of the cytosol consisting of all cytosol that is part of the postsynapse. GO:0002616 regulation of macrophage antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002616 Any process that modulates the frequency, rate, or extent of macrophage antigen processing and presentation. GO:0099525 presynaptic dense core vesicle exocytosis biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099525 The secretion of molecules (e.g. neuropeptides and neuromodulators such as serotonin and dopamine) contained within a membrane-bounced dense in response to increased presynaptic cytosolic calcium levels. GO:0002617 negative regulation of macrophage antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002617 down-regulation of macrophage antigen processing and presentation|downregulation of macrophage antigen processing and presentation|down regulation of macrophage antigen processing and presentation|inhibition of macrophage antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of macrophage antigen processing and presentation. GO:0099577 regulation of translation at presynapse, modulating synaptic transmission biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099577 Any process that modulates synaptic transmission by regulating translation occurring at the presynapse. GO:0099578 regulation of translation at postsynapse, modulating synaptic transmission biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099578 Any process that modulates synaptic transmission by regulating translation occurring at the postsynapse. GO:0099575 regulation of protein catabolic process at presynapse, modulating synaptic transmission biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099575 Any process that modulates synaptic transmission by regulating a catabolic process occurring at a presynapse. CHEBI:51549 benzisoxazole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51549 GO:0099576 regulation of protein catabolic process at postsynapse, modulating synaptic transmission biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099576 Any process that modulates synaptic transmission by regulating a catabolic process occurring at a postsynapse. GO:0099573 glutamatergic postsynaptic density biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099573 postsynaptic specialization, glutamatergic neuron-to-neuron synapse The post-synaptic specialization of a glutamatergic excitatory synapse. CHEBI:26587 rutinoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26587 GO:0099574 regulation of protein catabolic process at synapse, modulating synaptic transmission biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099574 Any process that modulates synaptic transmission by regulating protein degradation at the synapse. CHEBI:26588 1,3,5-triazines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26588 GO:0099571 postsynaptic cytoskeleton biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099571 The portion of the cytoskeleton contained within the postsynapse. CHEBI:51545 1,2-benzoxazoles biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51545 GO:0099572 postsynaptic specialization biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099572 A network of proteins within and adjacent to the postsynaptic membrane. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components. CHEBI:26580 rifamycins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26580 GO:0099579 G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099579 G-protein coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential A G protein-coupled neurotransmitter receptor activity, occurring in the postsynaptic membrane, involved in regulation of postsynaptic membrane potential. GO:0099588 positive regulation of postsynaptic cytosolic calcium concentration biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099588 Any process that increases the concentration of calcium ions in the postsynaptic cytosol. GO:0099589 serotonin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0099589 Combining with the biogenic amine serotonin and transmitting a signal across a membrane by activating some effector activity. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates. GO:0099586 release of sequestered calcium ion into postsynaptic cytosol biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099586 The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the postsynaptic cytosol. GO:0099587 inorganic ion import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099587 inorganic ion import into cell The directed movement of inorganic ions from outside of a cell, across the plasma membrane and into the cytosol. GO:0099585 release of sequestered calcium ion into presynaptic cytosol biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099585 The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the presynaptic cytosol. GO:0099582 neurotransmitter receptor activity involved in regulation of presynaptic cytosolic calcium ion concentration biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099582 neurotransmitter receptor activity involved in regulation of presynaptic cytosolic calcium levels Any neurotransmitter receptor activity that is involved in regulating the concentration of calcium in the presynaptic cytosol. GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium levels Any neurotransmitter receptor activity that is involved in regulating the concentration of calcium in the postsynaptic cytosol. GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099580 ion antiporter activity involved in regulation of post-synaptic membrane potential Any ion antiporter activity, occurring in the postsynaptic membrane, that is involved in regulation of postsynaptic membrane potential. GO:0099581 ATPase coupled ion transmembrane transporter activity involved in regulation of postsynaptic membrane potential biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099581 ATPase-coupled ion transmembrane transporter activity involved in regulation of postsynaptic membrane potential|ATPase coupled ion transmembrane transporter activity involved in regulation of post-synaptic membrane potential Any ATPase coupled ion transmembrane transporter activity, occurring in the postsynaptic membrane, that is involved in regulation of postsynaptic membrane potential. CHEBI:26596 salicylates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26596 CHEBI:26590 sabinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_26590 GO:0099555 trans-synaptic signaling by nitric oxide, modulating synaptic transmission biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099555 Cell-cell signaling between presynapse and postsynapse, via the release and reception of nitric oxide molecules, that modulates the synaptic transmission properties of the synapse. GO:0099556 trans-synaptic signaling by carbon monoxide, modulating synaptic transmission biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099556 Cell-cell signaling between presynapse and postsynapse, via the release and reception of carbon monoxide molecules, that modulates the synaptic transmission properties of the synapse. GO:0099553 trans-synaptic signaling by endocannabinoid, modulating synaptic transmission biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099553 Cell-cell signaling between presynapse and postsynapse, via the release and reception of endocannabinoid ligands, that modulates the synaptic transmission properties of the synapse. GO:0099554 trans-synaptic signaling by soluble gas, modulating synaptic transmission biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099554 Cell-cell signaling between presynapse and postsynapse, via the release and reception of gaseous molecules, that modulates the synaptic transmission properties of the synapse. GO:0099551 trans-synaptic signaling by neuropeptide, modulating synaptic transmission biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099551 Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of neuropeptide molecules, that modulates the synaptic transmission properties of the synapse. GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099552 Cell-cell signaling between presynapse and postsynapse, via the release and reception of lipid molecules, that modulates the synaptic transmission properties of the synapse. GO:0099550 trans-synaptic signaling, modulating synaptic transmission biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099550 Cell-cell signaling between presynapse and postsynapse, across the synaptic cleft, that modulates the synaptic transmission properties of the synapse. CHEBI:26568 ribosylamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26568 CHEBI:26561 ribonucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26561 CHEBI:26562 ribose phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26562 CHEBI:26563 ribose triphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26563 GO:0099559 maintenance of alignment of postsynaptic density and presynaptic active zone biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099559 The process by which alignment between postsynaptic density and presynaptic active zone is maintained. GO:0099557 trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099557 Cell-cell signaling between presynapse and postsynapse, mediated by transynaptic protein complexes, that modulates the synaptic transmission properties of the synapse. GO:0099558 maintenance of synapse structure biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099558 synaptic maintenance A process that preserves the structural organistation and orientation of a synaptic cellular component such as the synaptic cytoskeleton and molecular scaffolds. GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099566 regulation of postsynaptic cytosolic calcium levels Any process that regulates the concentration of calcium in the postsynaptic cytosol. GO:0099567 calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099567 regulation of postsynaptic cytosolic calcium ion concentration by calcium ion buffering|postsynaptic calcium ion buffering|calcium ion binding involved in regulation of postsynaptic cytosolic calcium levels The directed change of free calcium ion concentration in the postsynaptic cytosol via the reversible binding of calcium ions to calcium-binding proteins in the cytosol thereby modulating the spatial and temporal dynamics of changes in postsynaptic cytosolic calcium concentrations. GO:0099564 modification of synaptic structure, modulating synaptic transmission biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099564 Any process that modulates synaptic transmission via modification of the structure of the synapse. GO:0099565 chemical synaptic transmission, postsynaptic biolink:BiologicalProcess go-plus goslim_synapse|gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0099565 postsynaptic process involved in chemical synaptic transmission The part of synaptic transmission occurring in the post-synapse: a signal transduction pathway consisting of neurotransmitter receptor activation and its effects on postsynaptic membrane potential and the ionic composition of the postsynaptic cytosol. CHEBI:51510 (S)-benzoin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_51510 GO:0099562 maintenance of postsynaptic density structure biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099562 A process which maintains the organization and the arrangement of proteins in the presynaptic density. GO:0099563 modification of synaptic structure biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099563 synapse remodelling Any process that modifies the structure/morphology of a synapse. GO:0099560 synaptic membrane adhesion biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099560 synapse adhesion between pre- and post-synapse The attachment of presynaptic membrane to postsynaptic membrane via adhesion molecules that are at least partially embedded in the plasma membrane. GO:0099561 synaptic membrane adhesion to extracellular matrix biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099561 The binding of a synaptic membrane to the extracellular matrix via adhesion molecules. CHEBI:26573 ribulose phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26573 GO:0099568 cytoplasmic region biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0099568 Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm. GO:0099569 presynaptic cytoskeleton biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099569 The portion of the cytoskeleton contained within the presynapse. GO:0002588 positive regulation of antigen processing and presentation of peptide antigen via MHC class II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002588 upregulation of antigen processing and presentation of peptide antigen via MHC class II|up regulation of antigen processing and presentation of peptide antigen via MHC class II|activation of antigen processing and presentation of peptide antigen via MHC class II|stimulation of antigen processing and presentation of peptide antigen via MHC class II|positive regulation of peptide antigen processing and presentation via MHC class II|up-regulation of antigen processing and presentation of peptide antigen via MHC class II Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II. GO:0051511 negative regulation of unidimensional cell growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051511 down-regulation of unidimensional cell growth|downregulation of unidimensional cell growth|negative regulation of cell elongation|down regulation of unidimensional cell growth|inhibition of unidimensional cell growth Any process that stops, prevents, or reduces the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis. GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002589 regulation of peptide antigen processing and presentation via MHC class I Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I. GO:0051512 positive regulation of unidimensional cell growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051512 up regulation of unidimensional cell growth|positive regulation of cell elongation|upregulation of unidimensional cell growth|stimulation of unidimensional cell growth|up-regulation of unidimensional cell growth|activation of unidimensional cell growth Any process that activates or increases the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis. GO:0051510 regulation of unidimensional cell growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051510 regulation of cell elongation Any process that modulates the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis. GO:0002584 negative regulation of antigen processing and presentation of peptide antigen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002584 downregulation of antigen processing and presentation of peptide antigen|down regulation of antigen processing and presentation of peptide antigen|inhibition of antigen processing and presentation of peptide antigen|down-regulation of antigen processing and presentation of peptide antigen|negative regulation of peptide antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen. GO:0051515 positive regulation of monopolar cell growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051515 up regulation of monopolar cell growth|stimulation of monopolar cell growth|up-regulation of monopolar cell growth|upregulation of monopolar cell growth Any process that activates or increases the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell. GO:0051516 regulation of bipolar cell growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051516 Any process that modulates the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell. GO:0002585 positive regulation of antigen processing and presentation of peptide antigen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002585 upregulation of antigen processing and presentation of peptide antigen|stimulation of antigen processing and presentation of peptide antigen|up-regulation of antigen processing and presentation of peptide antigen|activation of antigen processing and presentation of peptide antigen|positive regulation of peptide antigen processing and presentation|up regulation of antigen processing and presentation of peptide antigen Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen. GO:0051513 regulation of monopolar cell growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051513 Any process that modulates the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell. GO:0002586 regulation of antigen processing and presentation of peptide antigen via MHC class II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002586 regulation of peptide antigen processing and presentation via MHC class II Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II. GO:0002587 negative regulation of antigen processing and presentation of peptide antigen via MHC class II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002587 down regulation of antigen processing and presentation of peptide antigen via MHC class II|downregulation of antigen processing and presentation of peptide antigen via MHC class II|negative regulation of peptide antigen processing and presentation via MHC class II|down-regulation of antigen processing and presentation of peptide antigen via MHC class II|inhibition of antigen processing and presentation of peptide antigen via MHC class II Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II. GO:0051514 negative regulation of monopolar cell growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051514 down-regulation of monopolar cell growth|inhibition of monopolar cell growth|down regulation of monopolar cell growth|downregulation of monopolar cell growth Any process that stops, prevents, or reduces the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell. GO:0002580 regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002580 regulation of peptide or polysaccharide antigen processing and presentation via MHC class II Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II. GO:0051519 activation of bipolar cell growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051519 Any process that initiates the inactive process of bipolar cell growth, polarized growth from both ends of a cell. GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002581 down regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|downregulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|negative regulation of peptide or polysaccharide antigen processing and presentation via MHC class II|down-regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|inhibition of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II. GO:0051517 negative regulation of bipolar cell growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051517 down regulation of bipolar cell growth|downregulation of bipolar cell growth|down-regulation of bipolar cell growth|inhibition of bipolar cell growth Any process that stops, prevents, or reduces the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell. GO:0002582 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002582 upregulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|up regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|activation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|stimulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|positive regulation of peptide or polysaccharide antigen processing and presentation via MHC class II|up-regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II. GO:0002583 regulation of antigen processing and presentation of peptide antigen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002583 regulation of peptide antigen processing and presentation Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen. GO:0051518 positive regulation of bipolar cell growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051518 up regulation of bipolar cell growth|stimulation of bipolar cell growth|up-regulation of bipolar cell growth|upregulation of bipolar cell growth Any process that activates or increases the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell. GO:1905920 positive regulation of CoA-transferase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905920 up regulation of CoA-transferase activity|upregulation of CoA-transferase activity|up-regulation of CoA-transferase activity|activation of CoA-transferase activity Any process that activates or increases the frequency, rate or extent of CoA-transferase activity. GO:1905921 regulation of acetylcholine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905921 regulation of acetylcholine synthesis|regulation of acetylcholine formation|regulation of acetylcholine biosynthesis|regulation of acetylcholine anabolism Any process that modulates the frequency, rate or extent of acetylcholine biosynthetic process. GO:1905922 negative regulation of acetylcholine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905922 downregulation of acetylcholine anabolism|down regulation of acetylcholine synthesis|down regulation of acetylcholine formation|downregulation of acetylcholine synthesis|downregulation of acetylcholine formation|down-regulation of acetylcholine anabolism|negative regulation of acetylcholine anabolism|down-regulation of acetylcholine biosynthetic process|down-regulation of acetylcholine synthesis|negative regulation of acetylcholine synthesis|negative regulation of acetylcholine biosynthesis|down-regulation of acetylcholine biosynthesis|inhibition of acetylcholine anabolism|down-regulation of acetylcholine formation|negative regulation of acetylcholine formation|inhibition of acetylcholine synthesis|downregulation of acetylcholine biosynthetic process|downregulation of acetylcholine biosynthesis|inhibition of acetylcholine formation|down regulation of acetylcholine biosynthesis|down regulation of acetylcholine biosynthetic process|inhibition of acetylcholine biosynthetic process|inhibition of acetylcholine biosynthesis|down regulation of acetylcholine anabolism Any process that stops, prevents or reduces the frequency, rate or extent of acetylcholine biosynthetic process. GO:1905923 positive regulation of acetylcholine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905923 upregulation of acetylcholine formation|up regulation of acetylcholine anabolism|activation of acetylcholine anabolism|positive regulation of acetylcholine anabolism|up-regulation of acetylcholine biosynthesis|up-regulation of acetylcholine biosynthetic process|activation of acetylcholine biosynthesis|activation of acetylcholine biosynthetic process|up regulation of acetylcholine synthesis|activation of acetylcholine synthesis|positive regulation of acetylcholine synthesis|up regulation of acetylcholine formation|activation of acetylcholine formation|positive regulation of acetylcholine formation|up-regulation of acetylcholine anabolism|positive regulation of acetylcholine biosynthesis|up regulation of acetylcholine biosynthetic process|up regulation of acetylcholine biosynthesis|up-regulation of acetylcholine synthesis|up-regulation of acetylcholine formation|upregulation of acetylcholine anabolism|upregulation of acetylcholine biosynthesis|upregulation of acetylcholine biosynthetic process|upregulation of acetylcholine synthesis Any process that activates or increases the frequency, rate or extent of acetylcholine biosynthetic process. GO:1905924 obsolete regulation of invadopodium assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905924 regulation of invadopodium formation OBSOLETE. Any process that modulates the frequency, rate or extent of invadopodium assembly. GO:1905925 obsolete negative regulation of invadopodium assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905925 down regulation of invadopodium assembly|downregulation of invadopodium formation|downregulation of invadopodium assembly|down regulation of invadopodium formation|inhibition of invadopodium formation|down-regulation of invadopodium assembly|inhibition of invadopodium assembly|down-regulation of invadopodium formation|negative regulation of invadopodium formation OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of invadopodium assembly. GO:1905926 obsolete positive regulation of invadopodium assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905926 up regulation of invadopodium formation|up regulation of invadopodium assembly|upregulation of invadopodium formation|activation of invadopodium assembly|up-regulation of invadopodium formation|activation of invadopodium formation|up-regulation of invadopodium assembly|positive regulation of invadopodium formation|upregulation of invadopodium assembly OBSOLETE. Any process that activates or increases the frequency, rate or extent of invadopodium assembly. GO:1905927 obsolete regulation of invadopodium disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905927 OBSOLETE. Any process that modulates the frequency, rate or extent of invadopodium disassembly. GO:1905928 obsolete negative regulation of invadopodium disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905928 downregulation of invadopodium disassembly|down regulation of invadopodium disassembly|inhibition of invadopodium disassembly|down-regulation of invadopodium disassembly OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of invadopodium disassembly. GO:1905929 obsolete positive regulation of invadopodium disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905929 upregulation of invadopodium disassembly|up-regulation of invadopodium disassembly|activation of invadopodium disassembly|up regulation of invadopodium disassembly OBSOLETE. Any process that activates or increases the frequency, rate or extent of invadopodium disassembly. GO:0002599 negative regulation of antigen processing and presentation of lipid antigen via MHC class Ib biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002599 negative regulation of lipid antigen processing and presentation via MHC class Ib|down-regulation of antigen processing and presentation of lipid antigen via MHC class Ib|inhibition of antigen processing and presentation of lipid antigen via MHC class Ib|down regulation of antigen processing and presentation of lipid antigen via MHC class Ib|downregulation of antigen processing and presentation of lipid antigen via MHC class Ib Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib. GO:0051522 activation of monopolar cell growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051522 Any process that initiates the inactive process of monopolar cell growth, polarized growth from one end of a cell. GO:0051523 cell growth mode switching, monopolar to bipolar biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051523 new end take off|NETO The process in which a cell switches from monopolar cell growth to bipolar cell growth. GO:0051520 termination of bipolar cell growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051520 Any process that stops the active process of bipolar cell growth, polarized growth from both ends of a cell. GO:0051521 termination of monopolar cell growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051521 Any process that stops the active process of bipolar cell growth, polarized growth from one end of a cell. GO:0051526 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051526 GO:0002595 regulation of antigen processing and presentation of peptide antigen via MHC class Ib biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002595 regulation of peptide antigen processing and presentation via MHC class Ib Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib. GO:0002596 negative regulation of antigen processing and presentation of peptide antigen via MHC class Ib biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002596 negative regulation of peptide antigen processing and presentation via MHC class Ib|down-regulation of antigen processing and presentation of peptide antigen via MHC class Ib|inhibition of antigen processing and presentation of peptide antigen via MHC class Ib|down regulation of antigen processing and presentation of peptide antigen via MHC class Ib|downregulation of antigen processing and presentation of peptide antigen via MHC class Ib Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib. GO:0051527 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051527 PR:000013246 prolactin biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000013246 PRL A somatotropin hormone family member that is a translation product of the human PRL gene or a 1:1 ortholog thereof. GO:0002597 positive regulation of antigen processing and presentation of peptide antigen via MHC class Ib biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002597 up regulation of antigen processing and presentation of peptide antigen via MHC class Ib|activation of antigen processing and presentation of peptide antigen via MHC class Ib|positive regulation of peptide antigen processing and presentation via MHC class Ib|stimulation of antigen processing and presentation of peptide antigen via MHC class Ib|up-regulation of antigen processing and presentation of peptide antigen via MHC class Ib|upregulation of antigen processing and presentation of peptide antigen via MHC class Ib Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib. GO:0051524 cell growth mode switching, bipolar to monopolar biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051524 The process in which a cell switches from bipolar cell growth to monopolar cell growth. GO:0051525 NFAT protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051525 NFATx binding|NFAT5 protein binding|nuclear factor of activated T cell protein binding|NFAT4 protein binding|NFAT3 protein binding|NFAT2 protein binding|NFAT1 protein binding|NFATp binding|NFAT binding|NFATc4 binding|NFATc3 binding|NFATc2 binding|NFATc1 binding|NFATc binding|non-calcium-regulated NFAT protein binding Interacting selectively and non-covalently with NFAT (nuclear factor of activated T cells) proteins, a family of transcription factors. NFAT proteins have crucial roles in the development and function of the immune system. PR:000013248 prolactin receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000013248 PRL-R|PRLR A protein that is a translation product of the human PRLR gene or a 1:1 ortholog thereof. GO:0002598 regulation of antigen processing and presentation of lipid antigen via MHC class Ib biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002598 regulation of lipid antigen processing and presentation via MHC class Ib Any process that modulates the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib. GO:0002591 positive regulation of antigen processing and presentation of peptide antigen via MHC class I biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002591 stimulation of antigen processing and presentation of peptide antigen via MHC class I|activation of antigen processing and presentation of peptide antigen via MHC class I|up-regulation of antigen processing and presentation of peptide antigen via MHC class I|positive regulation of peptide antigen processing and presentation via MHC class I|up regulation of antigen processing and presentation of peptide antigen via MHC class I|upregulation of antigen processing and presentation of peptide antigen via MHC class I Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I. GO:0002592 regulation of antigen processing and presentation via MHC class Ib biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002592 Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib. GO:0051528 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051528 GO:0002593 negative regulation of antigen processing and presentation via MHC class Ib biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002593 down-regulation of antigen processing and presentation via MHC class Ib|downregulation of antigen processing and presentation via MHC class Ib|down regulation of antigen processing and presentation via MHC class Ib|inhibition of antigen processing and presentation via MHC class Ib Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib. GO:0002594 positive regulation of antigen processing and presentation via MHC class Ib biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002594 upregulation of antigen processing and presentation via MHC class Ib|stimulation of antigen processing and presentation via MHC class Ib|up-regulation of antigen processing and presentation via MHC class Ib|activation of antigen processing and presentation via MHC class Ib|up regulation of antigen processing and presentation via MHC class Ib Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib. GO:0051529 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051529 GO:0002590 negative regulation of antigen processing and presentation of peptide antigen via MHC class I biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002590 down-regulation of antigen processing and presentation of peptide antigen via MHC class I|negative regulation of peptide antigen processing and presentation via MHC class I|downregulation of antigen processing and presentation of peptide antigen via MHC class I|down regulation of antigen processing and presentation of peptide antigen via MHC class I|inhibition of antigen processing and presentation of peptide antigen via MHC class I Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I. GO:1905930 regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905930 regulation of VSMC differentiation involved in phenotypic switching|regulation of vascular smooth muscle cell differentiation involved in phenotypic switching|regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|regulation of VSMC differentiation involved in phenotypic dimorphism Any process that modulates the frequency, rate or extent of vascular smooth muscle cell differentiation involved in phenotypic switching. GO:1905931 negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905931 inhibition of VSMC differentiation involved in phenotypic switching|down regulation of VSMC differentiation involved in phenotypic dimorphism|negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching|down-regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching|down-regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|negative regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|down-regulation of vascular smooth muscle cell differentiation involved in phenotypic switching|inhibition of VSMC differentiation involved in phenotypic dimorphism|inhibition of vascular associated smooth muscle cell differentiation involved in phenotypic switching|negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|down-regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|down regulation of VSMC differentiation involved in phenotypic switching|downregulation of vascular smooth muscle cell differentiation involved in phenotypic switching|downregulation of VSMC differentiation involved in phenotypic switching|inhibition of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|downregulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|negative regulation of VSMC differentiation involved in phenotypic dimorphism|down-regulation of VSMC differentiation involved in phenotypic dimorphism|down regulation of vascular smooth muscle cell differentiation involved in phenotypic switching|inhibition of vascular smooth muscle cell differentiation involved in phenotypic switching|down regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching|down regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|negative regulation of vascular smooth muscle cell differentiation involved in phenotypic switching|down regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|downregulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching|negative regulation of VSMC differentiation involved in phenotypic switching|down-regulation of VSMC differentiation involved in phenotypic switching|downregulation of VSMC differentiation involved in phenotypic dimorphism|downregulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|inhibition of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell differentiation involved in phenotypic switching. GO:1905932 positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905932 activation of vascular associated smooth muscle cell differentiation involved in phenotypic switching|up regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|up-regulation of vascular smooth muscle cell differentiation involved in phenotypic switching|activation of vascular smooth muscle cell differentiation involved in phenotypic switching|up-regulation of VSMC differentiation involved in phenotypic switching|positive regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|upregulation of VSMC differentiation involved in phenotypic dimorphism|up-regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|activation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|activation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|up-regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching|upregulation of VSMC differentiation involved in phenotypic switching|positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching|up-regulation of VSMC differentiation involved in phenotypic dimorphism|up regulation of vascular smooth muscle cell differentiation involved in phenotypic switching|up-regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|up regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|activation of VSMC differentiation involved in phenotypic dimorphism|upregulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching|up regulation of VSMC differentiation involved in phenotypic switching|positive regulation of VSMC differentiation involved in phenotypic switching|upregulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|activation of VSMC differentiation involved in phenotypic switching|upregulation of vascular smooth muscle cell differentiation involved in phenotypic switching|positive regulation of VSMC differentiation involved in phenotypic dimorphism|up regulation of VSMC differentiation involved in phenotypic dimorphism|upregulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|up regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell differentiation involved in phenotypic switching. GO:1905933 regulation of cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905933 Any process that modulates the frequency, rate or extent of cell fate determination. GO:1905934 negative regulation of cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905934 inhibition of cell fate determination|down regulation of cell fate determination|downregulation of cell fate determination|down-regulation of cell fate determination Any process that stops, prevents or reduces the frequency, rate or extent of cell fate determination. GO:1905935 positive regulation of cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905935 up-regulation of cell fate determination|upregulation of cell fate determination|up regulation of cell fate determination|activation of cell fate determination Any process that activates or increases the frequency, rate or extent of cell fate determination. GO:1905936 regulation of germ cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905936 Any process that modulates the frequency, rate or extent of germ cell proliferation. GO:1905937 negative regulation of germ cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905937 down regulation of germ cell proliferation|downregulation of germ cell proliferation|down-regulation of germ cell proliferation|inhibition of germ cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of germ cell proliferation. GO:1905938 positive regulation of germ cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905938 upregulation of germ cell proliferation|up regulation of germ cell proliferation|activation of germ cell proliferation|up-regulation of germ cell proliferation Any process that activates or increases the frequency, rate or extent of germ cell proliferation. GO:1905939 regulation of gonad development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905939 regulation of gonadogenesis Any process that modulates the frequency, rate or extent of gonad development. GO:0051533 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051533 GO:0002566 somatic diversification of immune receptors via somatic mutation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002566 The process in which immune receptor genes are diversified through somatic mutation. GO:0051534 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051534 GO:0002567 somatic diversification of FREP-based immune receptors biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002567 The process that results in the generation of sequence diversity of the FREP-based immune receptors of snails. GO:0075501 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075501 GO:0075502 endosome membrane permeabilization involved in viral entry into host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075502 viral entry into host cell via caveolae-mediated endocytosis followed by endosome membrane|viral entry into host cell via clathrin-mediated endocytosis followed by endosome membrane permeabilization Induction of endosome membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with the capsid. Occurs after internalization of the virus through the endosomal pathway, and results in delivery of the virus contents into the host cell cytoplasm. GO:0002568 somatic diversification of T cell receptor genes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002568 somatic diversification of TCR genes The somatic process that results in the generation of sequence diversity of T cell receptor genes. GO:0051531 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051531 GO:0051532 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051532 GO:0075503 fusion of virus membrane with host macropinosome membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075503 viral entry into host cell via macropinocytosis followed by membrane fusion with the endosome membrane|viral entry into host cell via macropinocytosis followed by membrane fusion with the host macropinosome membrane Fusion of a viral membrane with a host macropinosome membrane, that occurs after internalization of the virus through the endosomal pathway, and results in release of the viral contents into the host cell cytoplasm. GO:0002569 somatic diversification of immune receptors by N region addition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002569 The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of heavy chain immunoglobulin and T cell receptor genes. N regions are found at the V-D, D-D, V-J, and D-J recombinational junctions, depending on the immune receptor gene. GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002562 The process in which immune receptor genes are diversified through recombination of the germline genetic elements within a single genetic locus. GO:0051537 2 iron, 2 sulfur cluster binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051537 2 iron, 2 sulphur cluster binding|diiron disulphide cluster binding|2Fe-2S cluster binding|diiron disulfide cluster binding|2 Fe 2 S cluster binding|iron-sulphur cluster 2Fe-2S binding|iron-sulfur cluster 2Fe-2S binding Interacting selectively and non-covalently with a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands. GO:0075504 macropinosomal membrane permeabilization involved in viral entry into host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075504 viral entry into host cell via macropinocytosis followed by macropinosomal membrane permeabilization Induction of macropinosome membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with the capsid. Occurs after internalization of the virus in a macropinosome, and results in release of the viral contents from the macropinosome into the host cell cytoplasm. GO:0051538 3 iron, 4 sulfur cluster binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051538 triiron tetrasulfide cluster binding|iron-sulfur cluster 3Fe-4S binding|3Fe-4S cluster binding|3 Fe 4 S cluster binding|triiron tetrasulphide cluster binding|iron-sulphur cluster 3Fe-4S binding|3 iron, 4 sulphur cluster binding Interacting selectively and non-covalently with a 3 iron, 4 sulfur (3Fe-4S) cluster; this cluster consists of three iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. It is essentially a 4Fe-4S cluster with one iron missing. GO:0002563 somatic diversification of immune receptors via alternate splicing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002563 The process in which immune receptor genes are diversified through alternate splicing. GO:0075505 entry of intact viral capsid into host nucleus through nuclear pore complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075505 Viral penetration into the host nucleus where a viral capsid passes intact through the host nuclear pore complex (NPC). GO:0002564 alternate splicing of immunoglobulin genes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002564 alternate splicing of antibody genes The generation of alternate transcripts of immunoglobulin genes through alternate splicing of exons. GO:0051535 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051535 GO:0075506 entry of viral genome into host nucleus through nuclear pore complex via importin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075506 entry of viral genome into host nucleus via cellular importin transport through the nuclear pore complex Viral penetration into the host nucleus where the viral genome passes through the nuclear pore complex (NPC) using the cellular importin transport machinery. GO:0051536 iron-sulfur cluster binding biolink:MolecularActivity go-plus goslim_metagenomics http://purl.obolibrary.org/obo/GO_0051536 iron sulphur cluster binding|iron-sulphur cluster binding|iron sulfur cluster binding|Fe/S binding Interacting selectively and non-covalently with an iron-sulfur cluster, a combination of iron and sulfur atoms. GO:0002565 somatic diversification of immune receptors via gene conversion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002565 The process in which immune receptor genes are diversified through gene conversion. GO:0075507 entry of viral genome into host nucleus via docking of viral capsid to the nuclear pore complex and injection of viral genome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075507 Viral penetration into the host nucleus where the where a viral capsid docks on the cytoplasmic side of the nuclear pore complex (NPC) and ejects the viral genome through the pore into the nucleoplasm. GO:0075508 entry of viral genome into host nucleus via retainment of capsid in nuclear pore complex and release of genome into nucleoplasm biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075508 entry of viral genome into host nucleus via attachment of capsid to nuclear pore complex and release of genome into nucleoplasm Viral penetration into the host nucleus where a viral capsid enters the host nuclear pore complex (NPC) but remains attached to the pore on the nuclear side. The capsid then disassembles, releasing the viral genome into the nucleoplasm. GO:0075509 endocytosis involved in viral entry into host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075509 VZ:977 viral penetration via endocytosis followed by endosome disruption|virus endocytosis by host|viral entry into host cell via endocytosis Any endocytosis that is involved in the uptake of a virus into a host cell. GO:0051539 4 iron, 4 sulfur cluster binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051539 iron-sulfur cluster 4Fe-4S binding|tetrairon tetrasulfide cluster binding|4Fe-4S cluster binding|tetrairon tetrasulphide cluster binding|4 Fe 4 S cluster binding|iron-sulphur cluster 4Fe-4S binding|4 iron, 4 sulphur cluster binding Interacting selectively and non-covalently with a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. GO:0002560 basophil mediated immunity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002560 Any process involved in the carrying out of an immune response by a basophil. GO:0002561 basophil degranulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002561 The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a basophil. GO:1905940 negative regulation of gonad development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905940 down regulation of gonad development|down regulation of gonadogenesis|downregulation of gonad development|downregulation of gonadogenesis|down-regulation of gonad development|down-regulation of gonadogenesis|negative regulation of gonadogenesis|inhibition of gonad development|inhibition of gonadogenesis Any process that stops, prevents or reduces the frequency, rate or extent of gonad development. GO:1905941 positive regulation of gonad development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905941 upregulation of gonad development|upregulation of gonadogenesis|up regulation of gonad development|activation of gonad development|up regulation of gonadogenesis|activation of gonadogenesis|positive regulation of gonadogenesis|up-regulation of gonad development|up-regulation of gonadogenesis Any process that activates or increases the frequency, rate or extent of gonad development. GO:1905942 regulation of formation of growth cone in injured axon biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905942 Any process that modulates the frequency, rate or extent of formation of growth cone in injured axon. GO:1905943 negative regulation of formation of growth cone in injured axon biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905943 down-regulation of formation of growth cone in injured axon|downregulation of formation of growth cone in injured axon|down regulation of formation of growth cone in injured axon|inhibition of formation of growth cone in injured axon Any process that stops, prevents or reduces the frequency, rate or extent of formation of growth cone in injured axon. GO:1905944 positive regulation of formation of growth cone in injured axon biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905944 up-regulation of formation of growth cone in injured axon|activation of formation of growth cone in injured axon|up regulation of formation of growth cone in injured axon|upregulation of formation of growth cone in injured axon Any process that activates or increases the frequency, rate or extent of formation of growth cone in injured axon. GO:1905945 regulation of response to calcium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905945 regulation of response to Ca2+ ion Any process that modulates the frequency, rate or extent of response to calcium ion. GO:1905946 negative regulation of response to calcium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905946 downregulation of response to Ca2+ ion|downregulation of response to calcium ion|down regulation of response to Ca2+ ion|inhibition of response to Ca2+ ion|down-regulation of response to calcium ion|inhibition of response to calcium ion|negative regulation of response to Ca2+ ion|down-regulation of response to Ca2+ ion|down regulation of response to calcium ion Any process that stops, prevents or reduces the frequency, rate or extent of response to calcium ion. GO:1905947 positive regulation of response to calcium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905947 up regulation of response to Ca2+ ion|up regulation of response to calcium ion|activation of response to calcium ion|upregulation of response to Ca2+ ion|activation of response to Ca2+ ion|up-regulation of response to Ca2+ ion|up-regulation of response to calcium ion|upregulation of response to calcium ion|positive regulation of response to Ca2+ ion Any process that activates or increases the frequency, rate or extent of response to calcium ion. GO:1905948 ABC-type 3',5'-cyclic GMP transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1905948 ATP-dependent 3',5'-cyclic GMP transmembrane transporter activity|ATPase-coupled cGMP transmembrane transporter activity|ATPase-coupled 3',5'-cyclic GMP transmembrane transporter activity|3',5'-cyclic GMP transmembrane-transporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + 3',5'-cyclic GMP(in) = ADP + phosphate + 3',5'-cyclic GMP(out). GO:1905949 negative regulation of calcium ion import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905949 inhibition of calcium ion import across plasma membrane|down regulation of calcium ion import across plasma membrane|downregulation of calcium ion import across plasma membrane|down-regulation of calcium ion import across plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import across plasma membrane. GO:0051530 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051530 GO:0051544 positive regulation of elastin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051544 stimulation of elastin biosynthetic process|up-regulation of elastin biosynthetic process|activation of elastin biosynthetic process|up regulation of elastin biosynthetic process|upregulation of elastin biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin. GO:0002577 regulation of antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002577 Any process that modulates the frequency, rate, or extent of antigen processing and presentation. GO:0002578 negative regulation of antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002578 down-regulation of antigen processing and presentation|inhibition of antigen processing and presentation|down regulation of antigen processing and presentation|downregulation of antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation. GO:0051545 negative regulation of elastin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051545 down-regulation of elastin biosynthetic process|downregulation of elastin biosynthetic process|down regulation of elastin biosynthetic process|inhibition of elastin biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin. GO:0002579 positive regulation of antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002579 stimulation of antigen processing and presentation|up-regulation of antigen processing and presentation|upregulation of antigen processing and presentation|up regulation of antigen processing and presentation|activation of antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation. GO:0051542 elastin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051542 The chemical reactions and pathways resulting in the formation of elastin, a fibrous glycoprotein found in elastic tissues such as the walls of arteries. GO:0051543 regulation of elastin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051543 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin. GO:0051548 negative regulation of keratinocyte migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051548 down-regulation of keratinocyte migration|downregulation of keratinocyte migration|down regulation of keratinocyte migration|inhibition of keratinocyte migration Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte migration. GO:0002573 myeloid leukocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002573 myeloid leucocyte differentiation The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage. GO:0051549 positive regulation of keratinocyte migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051549 up regulation of keratinocyte migration|upregulation of keratinocyte migration|stimulation of keratinocyte migration|activation of keratinocyte migration|up-regulation of keratinocyte migration Any process that activates or increases the frequency, rate or extent of keratinocyte migration. GO:0002574 thrombocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002574 The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a thrombocyte, a nucleated cell found in all vertebrates but mammals involved in hemostasis. CHEBI:145656 galactoxylomannan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145656 GO:0051546 keratinocyte migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051546 The directed movement of a keratinocyte, epidermal cells which synthesize keratin, from one site to another. GO:0002575 basophil chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002575 The movement of a basophil in response to an external stimulus. GO:0051547 regulation of keratinocyte migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051547 Any process that modulates the frequency, rate or extent of keratinocyte migration. GO:0002576 platelet degranulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002576 platelet exocytosis The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet. GO:0002570 somatic diversification of immunoglobulin genes by N region addition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002570 somatic diversification of antibody genes by N region addition The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of heavy chain immunoglobulin genes. N regions are found at the V-D and D-J recombinational junctions. GO:0002571 somatic diversification of T cell receptor genes by N region addition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002571 somatic diversification of TCR genes by N region addition The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of T cell receptor genes. N regions are found at the V-D, D-D, V-J, and D-J recombinational junctions, depending on the T cell receptor gene. GO:0002572 pro-T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002572 pro-T lymphocyte differentiation The process in which a precursor cell type acquires the specialized features of a pro-T cell. Pro-T cells are the earliest stage of the T cell lineage but are not fully committed. GO:1905960 response to differentiation-inducing factor 2 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905960 response to DIF-2|response to DIF2|response to 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one stimulus. GO:1905950 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1905950 GO:1905951 mitochondrion DNA recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905951 DNA recombination in mitochondria Any DNA recombination that takes place in mitochondrion. GO:1905952 regulation of lipid localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905952 regulation of lipid localisation Any process that modulates the frequency, rate or extent of lipid localization. GO:1905953 negative regulation of lipid localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905953 down-regulation of lipid localization|downregulation of lipid localisation|down regulation of lipid localisation|inhibition of lipid localisation|downregulation of lipid localization|down regulation of lipid localization|inhibition of lipid localization|negative regulation of lipid localisation|down-regulation of lipid localisation Any process that stops, prevents or reduces the frequency, rate or extent of lipid localization. GO:1905954 positive regulation of lipid localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905954 up regulation of lipid localization|upregulation of lipid localisation|upregulation of lipid localization|up-regulation of lipid localisation|activation of lipid localisation|up-regulation of lipid localization|activation of lipid localization|positive regulation of lipid localisation|up regulation of lipid localisation Any process that activates or increases the frequency, rate or extent of lipid localization. GO:1905955 negative regulation of endothelial tube morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905955 down-regulation of endothelial tube morphogenesis|downregulation of endothelial tube morphogenesis|down regulation of endothelial tube morphogenesis|inhibition of endothelial tube morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of endothelial tube morphogenesis. GO:1905956 positive regulation of endothelial tube morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905956 up-regulation of endothelial tube morphogenesis|activation of endothelial tube morphogenesis|up regulation of endothelial tube morphogenesis|upregulation of endothelial tube morphogenesis Any process that activates or increases the frequency, rate or extent of endothelial tube morphogenesis. GO:1905957 regulation of cellular response to alcohol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905957 Any process that modulates the frequency, rate or extent of cellular response to alcohol. GO:1905958 negative regulation of cellular response to alcohol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905958 downregulation of cellular response to alcohol|down regulation of cellular response to alcohol|inhibition of cellular response to alcohol|down-regulation of cellular response to alcohol Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to alcohol. GO:1905959 positive regulation of cellular response to alcohol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905959 up regulation of cellular response to alcohol|upregulation of cellular response to alcohol|up-regulation of cellular response to alcohol|activation of cellular response to alcohol Any process that activates or increases the frequency, rate or extent of cellular response to alcohol. GO:0051540 metal cluster binding biolink:MolecularActivity go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0051540 Interacting selectively and non-covalently with a cluster of atoms including both metal ions and nonmetal atoms, usually sulfur and oxygen. Examples include iron-sulfur clusters and nickel-iron-sulfur clusters. GO:0051541 elastin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051541 elastin metabolism The chemical reactions and pathways involving elastin, a glycoprotein which is randomly coiled and crosslinked to form elastic fibers that are found in connective tissue. GO:0075522 IRES-dependent viral translational initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075522 VZ:867 Process by which viral mRNA translation is initiated, where a domain in the 5' untranslated region (UTR) of the viral mRNA called an internal ribosome entry site (IRES) binds the host 43S preinitiation complex, circumventing regular cap-dependent translation initiation. GO:0002544 chronic inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002544 Inflammation of prolonged duration (weeks or months) in which active inflammation, tissue destruction, and attempts at repair are proceeding simultaneously. Although it may follow acute inflammation, chronic inflammation frequently begins insidiously, as a low-grade, smoldering, often asymptomatic response. GO:0051555 flavonol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051555 MetaCyc:PWY-3101 The chemical reactions and pathways resulting in the formation of flavonols, a member of a class of vascular pigments formed by consecutive oxidative processes from the flavonoid intermediates flavanones and dihydroflavonols. Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities. GO:0075523 viral translational frameshifting biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075523 VZ:860 ribosomal frameshifting involved in viral translation A process which occurs during viral translation, which involves a translational recoding mechanism called programmed ribosomal frameshifting. This causes the ribosome to alter its reading of the mRNA to an a different open reading frame to produce alternate viral proteins. GO:0002545 chronic inflammatory response to non-antigenic stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002545 A chronic inflammatory response to a non-antigenic stimulus such as heat or physical trauma. GO:0051556 leucoanthocyanidin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051556 MetaCyc:PWY1F-823 leucoanthocyanidin metabolism The chemical reactions and pathways involving leucoanthocyanidins, a class of colorless intermediates in the biosynthetic pathway of the pigmented flavonoids. GO:0002546 negative regulation of tissue kallikrein-kinin cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002546 down regulation of tissue kallikrein-kinin cascade|downregulation of tissue kallikrein-kinin cascade|negative regulation of glandular kallikrein-kinin cascade|down-regulation of tissue kallikrein-kinin cascade|inhibition of tissue kallikrein-kinin cascade Any process that stops, prevents, or reduces the frequency, rate, or extent of the tissue kallikrein-kinin cascade. GO:0075524 ribosomal skipping biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075524 VZ:914 A translation process in which a specific viral peptide prevents the ribosome from covalently linking a new inserted amino acid, and lets it continue translation, thereby cleaving the nascent protein while allowing translation to continue. GO:0051553 flavone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051553 2-phenylchromone biosynthesis|2-phenylchromone biosynthetic process|2-phenyl-4H-1-benzopyran-4-one biosynthesis|2-phenyl-4H-1-benzopyran-4-one biosynthetic process The chemical reactions and pathways resulting in the formation of flavones, a class of pigmented plant compounds based on 2-phenyl-4H-1-benzopyran-4-one (2-phenylchromone). GO:0075525 viral translational termination-reinitiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075525 VZ:858 viral translation involving termination re-initiation|viral translation involving translational stop-start|termination reinitiation involved in viral translation|viral translation involving termination-reinitiation A process which occurs as part of viral mRNA translation which allows expression of a downstream open reading frame (ORF) in a dicistronic mRNA. In this process, ribosomes translate the upstream ORF but following termination, a proportion of 40S subunits remain tethered to the mRNA and go on to re-initiate translation at the start codon of the downstream ORF. GO:0002547 positive regulation of tissue kallikrein-kinin cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002547 up regulation of tissue kallikrein-kinin cascade|activation of tissue kallikrein-kinin cascade|positive regulation of glandular kallikrein-kinin cascade|stimulation of tissue kallikrein-kinin cascade|up-regulation of tissue kallikrein-kinin cascade|upregulation of tissue kallikrein-kinin cascade Any process that activates or increases the frequency, rate, or extent of the tissue kallikrein-kinin cascade. GO:0051554 flavonol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051554 flavonol metabolism The chemical reactions and pathways involving flavonols, a member of a class of vascular pigments formed by consecutive oxidative processes from the flavonoid intermediates flavanones and dihydroflavonols. Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities. GO:0002540 leukotriene production involved in inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002540 leukotriene production involved in acute inflammatory response The synthesis or release of any leukotriene following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. GO:0075526 cap snatching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075526 VZ:839 cap snatching involved in viral mRNA transcription A transcription initiation process during which a nucleotide sequence between 10 and 20 nucleotides in size is cleaved from the 5' end of host mRNAs by a viral RNA-dependent polymerase. The capped leader sequence obtained is subsequently used to prime transcription on the viral genome, which ultimately leads to the synthesis of capped, translatable viral mRNAs. GO:0051559 phlobaphene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051559 The chemical reactions and pathways resulting in the formation of phlobaphenes, red pigments with oligomeric or polymeric structure derived from the flavonoid intermediate flavan-4-ols. GO:0075527 viral RNA editing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075527 VZ:857 RNA editing involved in viral mRNA transcription The process by which bases in viral mRNA are chemically altered during viral transcription. This is usually the incorporation of 1 - 6 additional nucleotides, which shifts the reading frame, allowing the generation of different protein products or through a specific nucleotide change that eliminates the termination codon. GO:0002541 activation of plasma proteins involved in acute inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002541 Any process activating plasma proteins by proteolysis as part of an acute inflammatory response. GO:0075528 modulation by virus of host immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075528 regulation by virus of host immune system process The process in which a virus effects a change in the host immune response. GO:0051557 leucoanthocyanidin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051557 The chemical reactions and pathways resulting in the formation of leucoanthocyanidins, a class of colorless intermediates in the biosynthetic pathway of the pigmented flavonoids. GO:0002542 Factor XII activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002542 Hageman factor activation Any process that activates Factor XII (Hageman factor). Factor XII is a protein synthesized by the liver that circulates in an inactive form until it encounters collagen or basement membrane or activated platelets (as occurs at the site of endothelial injury). Factor XII then undergoes a conformational change (becoming factor XIIa), exposing an active serine center that can subsequently cleave protein substrates and activate a variety of mediator systems. Factor XII is a participant in the clotting cascade as well as the kinin cascade. GO:0075529 establishment of latency as a circular episome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075529 establishment of latency as a circular plasmid|establishment of circular plasmid latency A process by which a virus establishes a latent state within its host as an episome, where the viral genome remains silent in the cytoplasm or nucleus as a circular structure. GO:0002543 activation of blood coagulation via clotting cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002543 activation of clotting cascade Any process that initiates the clotting cascade of blood coagulation, a cascade of plasma enzymes that is triggered following damage to blood vessels, leading to formation of a clot. GO:0051558 phlobaphene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051558 phlobaphene metabolism The chemical reactions and pathways involving phlobaphenes, red pigments with oligomeric or polymeric structure derived from the flavonoid intermediate flavan-4-ols. GO:1905961 protein-cysteine S-palmitoyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1905961 Palmitoyltransferase ERF2/SHR5 complex|Palmitoyltransferase ERF2-SHR5 complex A protein complex which is capable of protein-cysteine S-palmitoyltransferase activity. GO:1905962 glutamatergic neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905962 The process in which a relatively unspecialized cell acquires the specialized features of a glutamatergic neuron. GO:1905963 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1905963 GO:1905964 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1905964 GO:1905965 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1905965 GO:0002548 monocyte chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002548 The movement of a monocyte in response to an external stimulus. GO:0051551 aurone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051551 benzalcoumaran-3-one biosynthesis|benzalcoumaran-3-one biosynthetic process The chemical reactions and pathways resulting in the formation of aurones, a series of yellow plant pigments. GO:0051552 flavone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051552 2-phenyl-4H-1-benzopyran-4-one metabolism|flavone metabolism|2-phenyl-4H-1-benzopyran-4-one metabolic process|2-phenylchromone metabolic process|2-phenylchromone metabolism The chemical reactions and pathways involving flavones, a class of pigmented plant compounds based on 2-phenyl-4H-1-benzopyran-4-one (2-phenylchromone). GO:0002549 negative regulation of plasma kallikrein-kinin cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002549 downregulation of plasma kallikrein-kinin cascade|down-regulation of plasma kallikrein-kinin cascade|inhibition of plasma kallikrein-kinin cascade|down regulation of plasma kallikrein-kinin cascade Any process that stops, prevents, or reduces the frequency, rate, or extent of the plasma kallikrein-kinin cascade. GO:0075520 actin-dependent intracellular transport of virus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075520 VZ:991 actin-dependent intracellular transport of viral material The directed movement of a virus, or part of a virus, within the host cell cytoplasm via the host's actin filaments. Actin-dependent transport is induced by viral proteins that interact with actin and/or host cell motor proteins like myosins or that promotes actin polymerization/depolymerization reactions. GO:0051550 aurone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051550 aurone metabolism|benzalcoumaran-3-one metabolic process|benzalcoumaran-3-one metabolism The chemical reactions and pathways involving aurones, a series of plant flavonoids that provide a yellow colour to flowers. They have the basic skeletal structure of two benzene rings joined by a linear C3 chain (C6-C3-C6). Aurones exist mostly as 6-O-glucosides. GO:0075521 microtubule-dependent intracellular transport of viral material towards nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075521 VZ:983 microtubule-dependent intracellular transport of viral material to nucleus The directed movement of a virus, or part of a virus, towards the host cell nucleus using host microtubules. GO:0099500 vesicle fusion to plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099500 Fusion of the membrane of a vesicle with the plasma membrane, thereby releasing its contents into the extracellular space. GO:0051566 anthocyanidin-3-glucoside rhamnosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051566 3RT activity|anthocyanidin 3-glucoside-rhamnosyltransferase activity Catalysis of the reaction: anthocyanidin 3-glucoside + UDP-rhamnose = anthocyanidin 3-rutinoside + UDP. GO:0075511 macropinosome lysis involved in viral entry into host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075511 Viral-induced lysis of the macropinosome involved in the uptake of a virus into a host cell. Occurs after internalization of the virus in a macropinosome, and results in the release of viral contents from the macropinosome into the host cell cytoplasm. GO:0002555 histamine secretion by platelet biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002555 The regulated release of histamine by a platelet or group of platelets. GO:0051567 histone H3-K9 methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051567 histone lysine H3 K9 methylation|histone H3K9me|histone H3 K9 methylation The modification of histone H3 by addition of one or more methyl groups to lysine at position 9 of the histone. GO:0075512 clathrin-dependent endocytosis of virus by host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075512 VZ:957 viral penetration via clathrin-mediated endocytosis|viral entry into host cell via clathrin-mediated endocytosis followed by endosome lysis|viral entry into host cell via clathrin-mediated endocytosis|clathrin-mediated endocytosis of virus by host cell Any clathrin-mediated endocytosis that is involved in the uptake of a virus into a host cell. Begins by invagination of a specific region of the host cell plasma membrane around the bound virus to form a clathrin-coated pit, which then pinches off to form a clathrin-coated endocytic vesicle containing the virus. GO:0099501 exocytic vesicle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0099501 secretory vesicle membrane The lipid bilayer surrounding an exocytic vesicle. GO:0002556 serotonin secretion by basophil biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002556 serotonin release by basophil The regulated release of serotonin by a basophil or group of basophils. GO:0051564 positive regulation of smooth endoplasmic reticulum calcium ion concentration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051564 elevation of smooth endoplasmic reticulum calcium ion concentration|smooth endoplasmic reticulum calcium ion concentration elevation|elevation of smooth ER calcium ion concentration|elevation of calcium ion concentration in smooth endoplasmic reticulum Any process that increases the concentration of calcium ions in the smooth endoplasmic reticulum. GO:0075513 caveolin-mediated endocytosis of virus by host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075513 VZ:976 viral penetration via caveolae-mediated endocytosis followed by endosome disruption|viral entry into host cell via caveolae-mediated endocytosis|viral entry into host cell via caveolin-mediated endocytosis Any caveolin-mediated endocytosis that is involved in the uptake of a virus into a host cell. Begins when material is taken up into plasma membrane caveolae - specialized lipid rafts that form 50-70 nm flask-shaped invaginations of the plasma membrane - which then pinch off to form endocytic caveolar carriers containing the virus. GO:0002557 histamine secretion by basophil biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002557 The regulated release of histamine by a basophil or group of basophils. GO:0075514 endosome lysis involved in viral entry into host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075514 viral entry into host cell via caveolae-mediated endocytosis followed by endosome lysis Viral-induced lysis of the endosome involved in uptake of a virus into a host cell. Occurs after internalization of the virus through the endosomal pathway, and results in release of the viral contents from the endosome into the host cell cytoplasm. GO:0051565 negative regulation of smooth endoplasmic reticulum calcium ion concentration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051565 smooth endoplasmic reticulum calcium ion concentration reduction|reduction of smooth ER calcium ion concentration|reduction of calcium ion concentration in smooth ER|reduction of calcium ion concentration in smooth endoplasmic reticulum|reduction of smooth endoplasmic reticulum calcium ion concentration|smooth ER calcium ion concentration reduction Any process that decreases the concentration of calcium ions in the smooth endoplasmic reticulum. GO:0002558 type I hypersensitivity mediated by mast cells biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002558 An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors on mast cells, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines. GO:0075515 obsolete viral entry into host cell via caveolin-mediated endocytosis followed by genetic injection through the endosome membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075515 viral entry into host cell via caveolin-mediated endocytosis followed by genetic injection through the endosome membrane|viral entry into host cell via caveolae-mediated endocytosis followed by genetic injection through the endosome membrane OBSOLETE. The uptake of a virus into a host cell that begins when material is taken up into plasma membrane caveolae which then pinch off to form endocytic caveolar carriers containing the virus. The caveolar carriers then deliver their viral content to early endosomes, and the process ends when viral nucleic acid is released into the host cytoplasm by its injection through the endosome membrane. GO:0002551 mast cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002551 The movement of a mast cell in response to an external stimulus. GO:0075516 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075516 GO:0002552 serotonin secretion by mast cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002552 serotonin release by mast cell The regulated release of serotonin by a mast cell or group of mast cells. GO:0075517 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075517 GO:0051568 histone H3-K4 methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051568 histone lysine H3 K4 methylation|histone H3K4me|histone H3 K4 methylation The modification of histone H3 by addition of one or more methyl groups to lysine at position 4 of the histone. GO:0002553 histamine secretion by mast cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002553 The regulated release of histamine by a mast cell or group of mast cells. GO:0051569 regulation of histone H3-K4 methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051569 Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3. GO:0075518 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075518 GO:0002554 serotonin secretion by platelet biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002554 serotonin release by platelet The regulated release of serotonin by a platelet or group of platelets. GO:0075519 microtubule-dependent intracellular transport of viral material biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075519 The directed movement of the viral genome or viral particle within the host cell cytoplasm along host microtubules. Microtubule-dependent transport involves motor proteins like dynein and kinesin and is mostly used by viruses that target their genomes to the nucleus. GO:0002550 positive regulation of plasma kallikrein-kinin cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002550 upregulation of plasma kallikrein-kinin cascade|up regulation of plasma kallikrein-kinin cascade|activation of plasma kallikrein-kinin cascade|stimulation of plasma kallikrein-kinin cascade|up-regulation of plasma kallikrein-kinin cascade Any process that activates or increases the frequency, rate, or extent of the plasma kallikrein-kinin cascade. GO:0099508 voltage-gated ion channel activity involved in regulation of presynaptic membrane potential biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099508 voltage-dependent ion channel activity involved in regulation of pre-synaptic membrane potential|voltage gated ion channel activity involved in regulation of presynaptic membrane potential|voltage-dependent ion channel activity involved in regulation of presynaptic membrane potential|voltage-gated ion channel activity involved in regulation of pre-synaptic membrane potential Voltage-gated ion channel activity, occurring in the presynaptic membrane, involved in regulation of presynaptic membrane potential. This is a key step in synaptic transmission, following the arrival of an action potential at the synapse. GO:0099509 regulation of presynaptic cytosolic calcium ion concentration biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099509 regulation of presynaptic cytosolic calcium levels Any process that regulates the concentration of calcium in the presynaptic cytosol. GO:0099506 synaptic vesicle transport along actin filament biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099506 The directed movement of synaptic vesicles along actin filaments within a cell, powered by molecular motors. GO:0099507 ligand-gated ion channel activity involved in regulation of presynaptic membrane potential biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099507 ligand gated ion channel activity involved in regulation of presynaptic membrane potential|ligand-dependent ion channel activity involved in regulation of presynaptic membrane potential|ligand-gated ion channel activity involved in regulation of pre-synaptic membrane potential|ligand-dependent ion channel activity involved in regulation of pre-synaptic membrane potential Any ligand-gated ion channel activity, occurring in the presynaptic membrane, that is involved in regulation of presynaptic membrane potential. GO:0051562 negative regulation of mitochondrial calcium ion concentration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051562 reduction of mitochondrial calcium ion concentration|reduction of calcium ion concentration in mitochondria|mitochondrial calcium ion concentration reduction|reduction of calcium ion concentration in mitochondrion Any process that decreases the concentration of calcium ions in mitochondria. GO:0099504 synaptic vesicle cycle biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099504 A biological process in which synaptic vesicles are loaded with neurotransmitters, move to the active zone, exocytose and are then recycled via endocytosis, ultimately leading to reloading with neurotransmitters. GO:0002559 type I hypersensitivity mediated by basophils biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002559 An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors basophils, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines. GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051563 regulation of smooth ER calcium ion concentration|smooth endoplasmic reticulum calcium ion concentration regulation|smooth ER calcium ion concentration regulation|regulation of calcium ion concentration in smooth endoplasmic reticulum|calcium ion homeostasis in smooth ER|smooth ER calcium ion homeostasis|calcium ion homeostasis in smooth endoplasmic reticulum|regulation of calcium ion concentration in smooth ER|regulation of smooth endoplasmic reticulum calcium ion concentration Any process involved in the maintenance of an internal steady state of calcium ions within the smooth endoplasmic reticulum of a cell or between the smooth endoplasmic reticulum and its surroundings. GO:0099505 regulation of presynaptic membrane potential biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099505 regulation of pre-synaptic membrane potential Any process that modulates the potential difference across a presynaptic membrane. GO:0051560 mitochondrial calcium ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051560 regulation of calcium ion concentration in mitochondria|calcium ion homeostasis in mitochondrion|mitochondrial calcium ion concentration regulation|calcium ion homeostasis in mitochondria|regulation of mitochondrial calcium ion concentration|regulation of calcium ion concentration in mitochondrion Any process involved in the maintenance of an internal steady state of calcium ions within the cytoplasm of a cell or between mitochondria and their surroundings. GO:0099502 calcium-dependent activation of synaptic vesicle fusion biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099502 The regulatory process by which increased cytosolic calcium levels lead to the the fusion of synaptic vesicles with the presynaptic active zone membrane by bringing primed synaptic vesicle membrane into contact with membrane presynaptic active zone membrane. GO:0075510 macropinocytosis involved in viral entry into host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075510 VZ:800 viral entry into host cell via macropinocytosis Any macropinocytosis that is involved in the uptake of a virus into a host cell. GO:0051561 positive regulation of mitochondrial calcium ion concentration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051561 elevation of calcium ion concentration in mitochondrion|mitochondrial calcium ion concentration elevation|elevation of mitochondrial calcium ion concentration|elevation of calcium ion concentration in mitochondria Any process that increases the concentration of calcium ions in mitochondria. GO:0099503 secretory vesicle biolink:CellularComponent go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0099503 A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space. GO:0002522 leukocyte migration involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002522 immune cell migration during immune response|immune cell trafficking during immune response|leukocyte trafficking during immune response|leucocyte migration during immune response|leucocyte trafficking during immune response The movement of a leukocyte within or between different tissues and organs of the body as part of an immune response. GO:0051577 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051577 GO:0002523 leukocyte migration involved in inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002523 leukocyte trafficking during inflammatory response|leucocyte migration during inflammatory response|leukocyte migration during inflammatory response|leucocyte trafficking during inflammatory response|immune cell migration during inflammatory response|immune cell trafficking during inflammatory response The movement of a leukocyte within or between different tissues and organs of the body contributing to an inflammatory response. GO:0051578 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051578 GO:0002524 hypersensitivity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002524 Wikipedia:Hypersensitivity hypersensitivity response An inflammatory response to an exogenous environmental antigen or an endogenous antigen initiated by the adaptive immune system. GO:0051575 5'-deoxyribose-5-phosphate lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051575 dRP lyase activity|dRPase activity|5'-deoxyribose phosphate activity Catalysis of the beta-elimination of the 5' deoxyribose-5-phosphate at an abasic site in DNA where a DNA-(apurinic or apyrimidinic site) lyase has already cleaved the C-O-P bond 3' to the apurinic or apyrimidinic site. GO:0002525 acute inflammatory response to non-antigenic stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002525 An acute inflammatory response to non-antigenic stimuli such as heat or physical trauma. GO:0051576 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051576 GO:0002520 immune system development biolink:BiologicalProcess go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0002520 The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process. GO:0051579 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051579 GO:0002521 leukocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002521 leucocyte differentiation|immune cell differentiation The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue. GO:0051570 regulation of histone H3-K9 methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051570 Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3. GO:0002526 acute inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002526 Inflammation which comprises a rapid, short-lived, relatively uniform response to acute injury or antigenic challenge and is characterized by accumulations of fluid, plasma proteins, and granulocytic leukocytes. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response. GO:0051573 negative regulation of histone H3-K9 methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051573 down regulation of histone H3-K9 methylation|downregulation of histone H3-K9 methylation|down-regulation of histone H3-K9 methylation|inhibition of histone H3-K9 methylation Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3. CHEBI:51480 (5S)-albaflavenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_51480 GO:0051574 positive regulation of histone H3-K9 methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051574 upregulation of histone H3-K9 methylation|up regulation of histone H3-K9 methylation|activation of histone H3-K9 methylation|stimulation of histone H3-K9 methylation|up-regulation of histone H3-K9 methylation Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3. GO:0002527 vasodilation involved in acute inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002527 vasodilation during acute inflammatory response An increase in the internal diameter of blood vessels, especially arterioles or capillaries, usually resulting in a decrease in blood pressure contributing to an acute inflammatory response. GO:0051571 positive regulation of histone H3-K4 methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051571 upregulation of histone H3-K4 methylation|up regulation of histone H3-K4 methylation|activation of histone H3-K4 methylation|stimulation of histone H3-K4 methylation|up-regulation of histone H3-K4 methylation Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3. GO:0002528 regulation of vascular permeability involved in acute inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002528 regulation of vascular permeability during acute inflammatory response Any process that modulates the extent to which blood vessels can be pervaded by fluid contributing to an acute inflammatory response. GO:0002529 regulation of plasma kallikrein-kinin cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002529 Any process that modulates the frequency, rate, or extent of the plasma kallikrein-kinin cascade. GO:0051572 negative regulation of histone H3-K4 methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051572 down regulation of histone H3-K4 methylation|downregulation of histone H3-K4 methylation|down-regulation of histone H3-K4 methylation|inhibition of histone H3-K4 methylation Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3. GO:0051588 regulation of neurotransmitter transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051588 Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0002533 lysosomal enzyme secretion involved in inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002533 secretion of lysosomal enzymes involved in inflammatory response|lysosomal enzyme secretion involved in acute inflammatory response|secretion of lysosomal enzymes involved in acute inflammatory response The regulated release of lysosomal enzymes by a cell as part of an inflammatory response. GO:0051589 negative regulation of neurotransmitter transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051589 inhibition of neurotransmitter transport|down-regulation of neurotransmitter transport|downregulation of neurotransmitter transport|down regulation of neurotransmitter transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0002534 cytokine production involved in inflammatory response biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0002534 cytokine production involved in acute inflammatory response The synthesis or release of a cytokine following a inflammatory stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. GO:0002535 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0002535 GO:0051586 positive regulation of dopamine uptake involved in synaptic transmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051586 up regulation of dopamine uptake involved in synaptic transmission|activation of dopamine uptake involved in synaptic transmission|stimulation of dopamine uptake involved in synaptic transmission|up-regulation of dopamine uptake involved in synaptic transmission|positive regulation of dopamine import involved in synaptic transmission|upregulation of dopamine uptake involved in synaptic transmission Any process that activates or increases the frequency, rate or extent of the directed movement of dopamine into a cell. GO:0002536 respiratory burst involved in inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002536 respiratory burst involved in acute inflammatory response|oxidative burst during acute inflammatory response|production of reactive oxygen species during acute inflammatory response A phase of elevated metabolic activity, during which oxygen consumption increases following a stimulus as part of an inflammatory response; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals, resulting in an increase in their intracellular or extracellular levels. GO:0051587 inhibition of dopamine uptake involved in synaptic transmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051587 inhibition of dopamine import involved in synaptic transmission Any process that prevents the activation of the directed movement of dopamine into a cell. GO:0002530 regulation of systemic arterial blood pressure involved in acute-phase response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002530 regulation of systemic arterial blood pressure during acute phase response|blood pressure regulation during acute phase response Any process that modulates the force with which blood travels through the circulatory system that contributes to the acute phase response. The acute phase response occurs during the early phases of an infection and is marked by changes in the production of plasma proteins such as C-reactive protein. CHEBI:51478 albaflavenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_51478 GO:0002531 regulation of heart contraction involved in acute-phase response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002531 regulation of cardiac contraction during acute phase response|regulation of heart contraction during acute phase response Any process that modulates the frequency, rate or extent of heart contraction that contributes to the acute phase response. The acute phase response occurs during the early phases of an infection and is marked by changes in the production of plasma proteins such as C-reactive protein. CHEBI:51479 (5R)-albaflavenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_51479 GO:0002532 production of molecular mediator involved in inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002532 production of molecular mediator involved in acute inflammatory response|production of cellular mediator of acute inflammation The synthesis or release of any molecular mediator of the inflammatory response following an inflammatory stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0051580 regulation of neurotransmitter uptake biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0051580 regulation of neurotransmitter import|regulation of neurotransmitter reuptake Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell. NCBITaxon:422676 Aconoidasida organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_422676 Hematozoa Vivier 1982 GO:0051581 negative regulation of neurotransmitter uptake biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051581 negative regulation of neurotransmitter import|down regulation of neurotransmitter uptake|downregulation of neurotransmitter uptake|down-regulation of neurotransmitter uptake Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell. CHEBI:51475 naphthohydroquinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51475 GO:0002537 nitric oxide production involved in inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002537 production of nitric oxide involved in inflammatory response|production of nitric oxide involved in acute inflammatory response|nitric oxide production involved in acute inflammatory response The synthesis or release of nitric oxide following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. GO:0051584 regulation of dopamine uptake involved in synaptic transmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051584 regulation of dopamine import involved in synaptic transmission Any process that modulates the frequency, rate or extent of the directed movement of the catecholamine neurotransmitter dopamine into a cell. GO:0075530 establishment of latency as a linear episome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075530 establishment of linear plasmid latency|establishment of latency as a linear plasmid A process by which a virus establishes a latent state within its host as an episome, where the viral genome remains silent in the cytoplasm or nucleus as linear structure. GO:0051585 negative regulation of dopamine uptake involved in synaptic transmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051585 down regulation of dopamine uptake involved in synaptic transmission|downregulation of dopamine uptake involved in synaptic transmission|down-regulation of dopamine uptake involved in synaptic transmission|negative regulation of dopamine import involved in synaptic transmission Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of dopamine into a presynaptic neuron or glial cell. GO:0002538 arachidonic acid metabolite production involved in inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002538 production of arachidonic acid metabolites involved in inflammatory response|arachidonic acid metabolite production involved in acute inflammatory response|production of arachidonic acid metabolites involved in acute inflammatory response The synthesis or release of products of arachidonic acid metabolism following a stimulus as part of an inflammatory response, resulting in an increase in their intracellular or extracellular levels. GO:0002539 prostaglandin production involved in inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002539 prostaglandin production involved in acute inflammatory response The synthesis or release of any prostaglandin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. GO:0051582 positive regulation of neurotransmitter uptake biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051582 up-regulation of neurotransmitter uptake|positive regulation of neurotransmitter import|upregulation of neurotransmitter uptake|up regulation of neurotransmitter uptake|activation of neurotransmitter uptake|stimulation of neurotransmitter uptake Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell. GO:0051583 dopamine uptake involved in synaptic transmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051583 dopamine import involved in synaptic transmission|dopamine reuptake involved in synaptic transmission The directed movement of dopamine into a presynaptic neuron or glial cell. In this context, dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline. CHEBI:75434 phytyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75434 CHEBI:75431 ghrelin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75431 CHEBI:75448 1-oleoyl-2-stearoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75448 CHEBI:75449 1-oleoyl-2-arachidonoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75449 CHEBI:75447 1-oleoyl-2-palmitoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75447 PR:000003858 aryl hydrocarbon receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000003858 AhR|AHR|class E basic helix-loop-helix protein 76|bHLHe76|Ah receptor A protein that is a translation product of the human AHR gene or a 1:1 ortholog thereof. CHEBI:75443 1-butyryl-2-oleoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75443 CHEBI:75457 2-linoleoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75457 CHEBI:75450 1-oleoyl-2-linoleoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75450 CHEBI:75455 2-palmitoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75455 CHEBI:75456 2-stearoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75456 CHEBI:75468 1-octadecanoyl-2-[(9Z)-octadecenoyl]-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75468 CHEBI:75462 1-octanoyl-2-oleoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75462 CHEBI:75463 1-lauroyl-2-oleoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75463 CHEBI:75466 1-palmitoyl-2-oleoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75466 CHEBI:75465 1-myristoyl-2-oleoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75465 CHEBI:75470 1-icosanoyl-2-oleoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75470 CHEBI:75471 1-linoleoyl-2-oleoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75471 CHEBI:75472 1-arachidonoyl-2-oleoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75472 CHEBI:75480 Ins-1-P-Cer-A 42:0(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75480 CHEBI:75481 Ins-1-P-Cer-A 44:0(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75481 CHEBI:75483 phytyl phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75483 GO:1905900 negative regulation of smooth muscle tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905900 down-regulation of smooth muscle tissue development|downregulation of smooth muscle tissue development|down regulation of smooth muscle tissue development|inhibition of smooth muscle tissue development Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle tissue development. GO:1905901 positive regulation of smooth muscle tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905901 activation of smooth muscle tissue development|up regulation of smooth muscle tissue development|upregulation of smooth muscle tissue development|up-regulation of smooth muscle tissue development Any process that activates or increases the frequency, rate or extent of smooth muscle tissue development. GO:1905902 regulation of mesoderm formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905902 Any process that modulates the frequency, rate or extent of mesoderm formation. GO:1905903 negative regulation of mesoderm formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905903 down-regulation of mesoderm formation|downregulation of mesoderm formation|down regulation of mesoderm formation|inhibition of mesoderm formation Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm formation. GO:1905904 positive regulation of mesoderm formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905904 up regulation of mesoderm formation|upregulation of mesoderm formation|activation of mesoderm formation|up-regulation of mesoderm formation Any process that activates or increases the frequency, rate or extent of mesoderm formation. NCBITaxon:2697495 Spiralia organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_2697495 GO:1905905 pharyngeal gland morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905905 glandulae pharyngeae morphogenesis|pharynx gland morphogenesis The developmental process by which a pharyngeal gland is generated and organized. GO:1905906 regulation of amyloid fibril formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905906 regulation of amyloid fibril assembly|regulation of amyloid structure formation|regulation of amyloid structure assembly Any process that modulates the frequency, rate or extent of amyloid fibril formation. GO:1905907 negative regulation of amyloid fibril formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905907 downregulation of amyloid fibril assembly|down-regulation of amyloid structure assembly|negative regulation of amyloid structure assembly|inhibition of amyloid structure formation|down-regulation of amyloid fibril formation|down regulation of amyloid structure formation|downregulation of amyloid structure assembly|negative regulation of amyloid fibril assembly|down-regulation of amyloid fibril assembly|downregulation of amyloid structure formation|down regulation of amyloid structure assembly|downregulation of amyloid fibril formation|down regulation of amyloid fibril formation|inhibition of amyloid structure assembly|negative regulation of amyloid structure formation|inhibition of amyloid fibril assembly|down-regulation of amyloid structure formation|inhibition of amyloid fibril formation|down regulation of amyloid fibril assembly Any process that stops, prevents or reduces the frequency, rate or extent of amyloid fibril formation. GO:1905908 positive regulation of amyloid fibril formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905908 activation of amyloid structure assembly|activation of amyloid fibril formation|up-regulation of amyloid fibril formation|up regulation of amyloid fibril assembly|positive regulation of amyloid structure assembly|upregulation of amyloid structure formation|positive regulation of amyloid fibril assembly|up regulation of amyloid structure assembly|activation of amyloid fibril assembly|up regulation of amyloid fibril formation|up regulation of amyloid structure formation|upregulation of amyloid structure assembly|up-regulation of amyloid fibril assembly|positive regulation of amyloid structure formation|activation of amyloid structure formation|upregulation of amyloid fibril formation|upregulation of amyloid fibril assembly|up-regulation of amyloid structure assembly|up-regulation of amyloid structure formation Any process that activates or increases the frequency, rate or extent of amyloid fibril formation. GO:1905909 regulation of dauer entry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905909 regulation of nematode entry into dormancy Any process that modulates the frequency, rate or extent of dauer entry. GO:0051500 D-tyrosyl-tRNA(Tyr) deacylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051500 Catalysis of the reaction: D-tyrosyl-tRNA(Tyr) = D-tyrosine + tRNA(Tyr). Hydrolysis of the removal of D-tyrosine from tyrosine residues in charged tRNA. GO:0051501 diterpene phytoalexin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051501 diterpene phytoalexin metabolism The chemical reactions and pathways involving diterpene phytoalexins, a class of diterpene formed in plants in response to fungal infection, physical damage, chemical injury, or a pathogenic process; they are sometimes referred to as plant antibiotics. Diterpenes are unsaturated hydrocarbons containing 20 carbon atoms and 4 branched methyl groups and are made up of isoprenoid units. GO:0051504 diterpene phytoalexin precursor biosynthetic process pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051504 MetaCyc:PWY-2981 diterpene phytoalexin precursor formation pathway|diterpene phytoalexin precursor anabolism pathway|diterpene phytoalexin precursor synthesis pathway A branched pathway that produces the precursors to four structurally distinct types of polycyclic diterpenes. The pathway starts with the cyclization of geranylgeranyl diphosphate into ent-copalyl diphosphate and syn-copalyl diphosphate. The catalytic conversion by diterpene cyclases of these two compounds produces the four diterpene hydrocarbons which are precursors to the four structurally distinct classes of diterpene phytoalexins. GO:0051505 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051505 GO:0051502 diterpene phytoalexin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051502 diterpene phytoalexin synthesis|diterpene phytoalexin formation|diterpene phytoalexin biosynthesis|diterpene phytoalexin anabolism The chemical reactions and pathways resulting in the formation of diterpene phytoalexins, terpenoids with 20 carbons produced by plants in response to environmental stresses. GO:0051503 adenine nucleotide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051503 The directed movement of adenine nucleotides, ATP, ADP, and/or AMP, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0051508 stigmasterol UDP-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051508 RHEA:61828|MetaCyc:RXN-12126 Catalysis of the reaction: UDP-glucose + stigmasterol = UDP + O-glucosyl-stigmasterol. GO:0051509 tomatidine UDP-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051509 Catalysis of the reaction: UDP-glucose + tomatidine = UDP + O-glucosyl-tomatidine. GO:0051506 ergosterol UDP-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051506 RHEA:61836|MetaCyc:RXN-16975) Catalysis of the reaction: UDP-glucose + ergosterol = UDP + O-glucosyl-ergosterol. GO:0051507 beta-sitosterol UDP-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051507 RHEA:61832|MetaCyc:RXN-12128 Catalysis of the reaction: UDP-glucose + a beta-sitosterol = UDP + O-glucosyl-beta-sitosterol. UBERON_CORE:transitively_anteriorly_connected_to transitively anteriorly connected to biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/uberon/core#transitively_anteriorly_connected_to transitively_anteriorly_connected_to . GO:1905910 negative regulation of dauer entry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905910 down regulation of dauer entry|downregulation of dauer entry|negative regulation of nematode entry into dormancy|down-regulation of nematode entry into dormancy|down-regulation of dauer entry|downregulation of nematode entry into dormancy|down regulation of nematode entry into dormancy|inhibition of dauer entry|inhibition of nematode entry into dormancy Any process that stops, prevents or reduces the frequency, rate or extent of dauer entry. GO:1905911 positive regulation of dauer entry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905911 upregulation of nematode entry into dormancy|upregulation of dauer entry|up-regulation of nematode entry into dormancy|activation of nematode entry into dormancy|up regulation of dauer entry|activation of dauer entry|positive regulation of nematode entry into dormancy|up regulation of nematode entry into dormancy|up-regulation of dauer entry Any process that activates or increases the frequency, rate or extent of dauer entry. GO:1905912 regulation of calcium ion export across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905912 regulation of calcium ion efflux from cell|regulation of calcium ion export from cell Any process that modulates the frequency, rate or extent of calcium ion export across the plasma membrane. GO:1905913 negative regulation of calcium ion export across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905913 downregulation of calcium ion export from cell|negative regulation of calcium ion efflux from cell|down-regulation of calcium ion efflux from cell|down regulation of calcium ion export from cell|inhibition of calcium ion export from cell|negative regulation of calcium ion export from cell|downregulation of calcium ion efflux from cell|down regulation of calcium ion efflux from cell|inhibition of calcium ion efflux from cell|down-regulation of calcium ion export from cell Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion export across the plasma membrane. GO:1905914 positive regulation of calcium ion export across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905914 up regulation of calcium ion export from cell|positive regulation of calcium ion efflux from cell|up regulation of calcium ion efflux from cell|upregulation of calcium ion export from cell|positive regulation of calcium ion export from cell|up-regulation of calcium ion export from cell|upregulation of calcium ion efflux from cell|activation of calcium ion export from cell|up-regulation of calcium ion efflux from cell|activation of calcium ion efflux from cell Any process that activates or increases the frequency, rate or extent of calcium ion export across the plasma membrane. GO:1905915 regulation of cell differentiation involved in phenotypic switching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905915 Any process that modulates the frequency, rate or extent of cell differentiation involved in phenotypic switching. GO:1905916 negative regulation of cell differentiation involved in phenotypic switching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905916 down regulation of cell differentiation involved in phenotypic switching|downregulation of cell differentiation involved in phenotypic switching|down-regulation of cell differentiation involved in phenotypic switching|inhibition of cell differentiation involved in phenotypic switching Any process that stops, prevents or reduces the frequency, rate or extent of cell differentiation involved in phenotypic switching. GO:1905917 positive regulation of cell differentiation involved in phenotypic switching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905917 upregulation of cell differentiation involved in phenotypic switching|up regulation of cell differentiation involved in phenotypic switching|activation of cell differentiation involved in phenotypic switching|up-regulation of cell differentiation involved in phenotypic switching Any process that activates or increases the frequency, rate or extent of cell differentiation involved in phenotypic switching. GO:1905918 regulation of CoA-transferase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905918 Any process that modulates the frequency, rate or extent of CoA-transferase activity. GO:1905919 negative regulation of CoA-transferase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905919 down regulation of CoA-transferase activity|inhibition of CoA-transferase activity|down-regulation of CoA-transferase activity|downregulation of CoA-transferase activity Any process that stops, prevents or reduces the frequency, rate or extent of CoA-transferase activity. CHEBI:26420 pyridinemonocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26420 CHEBI:26421 pyridines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26421 CHEBI:26437 pyrimidine nucleoside diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26437 CHEBI:26438 pyrimidine nucleoside monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26438 CHEBI:26439 pyrimidine nucleoside triphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26439 CHEBI:26433 pyrimidine 2'-deoxyribonucleoside diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26433 CHEBI:26434 pyrimidine 2'-deoxyribonucleoside monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26434 CHEBI:26435 pyrimidine deoxyribonucleoside triphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26435 CHEBI:26436 pyrimidine 2'-deoxyribonucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26436 CHEBI:26432 pyrimidine nucleobase biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_26432 CHEBI:26404 puromycins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26404 CHEBI:26406 N-substituted putrescine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26406 CHEBI:26407 pyrans biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26407 CHEBI:26400 purine ribonucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26400 CHEBI:26401 purines biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_26401 CHEBI:26416 pyridine alkaloid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26416 CHEBI:26413 pyrethroid insecticide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26413 CHEBI:26414 pyridazinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26414 CHEBI:26410 pyrazoles biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26410 CHEBI:75402 2-methyl-6-all-trans-nonaprenyl-1,4-benzoquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75402 CHEBI:75406 2-methyl-6-phytylhydroquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75406 CHEBI:75407 2,3-dimethyl-6-phytylhydroquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75407 CHEBI:75416 EC 6.1.1.* (ligases forming aminoacyl tRNA and related compounds) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75416 CHEBI:75414 platelet-activating factor receptor agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75414 GO:0036093 germ cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036093 The multiplication or reproduction of germ cells, reproductive cells in multicellular organisms, resulting in the expansion of a cell population. GO:0036094 small molecule binding biolink:MolecularActivity go-plus goslim_agr|goslim_flybase_ribbon http://purl.obolibrary.org/obo/GO_0036094 Interacting selectively and non-covalently with a small molecule, any low molecular weight, monomeric, non-encoded molecule. GO:0036095 obsolete positive regulation of invasive growth in response to glucose limitation by positive regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036095 transcriptional activation of genes involved in invasive growth OBSOLETE. Any process that activates or increases the frequency, rate or extent of invasive growth as a result of deprivation of glucose, by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:0036096 obsolete 3'-5'-exoribonuclease activity involved in pre-miRNA 3'-end processing biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036096 exonucleolytic trimming to generate 3' end of miRNA from pre-miRNA|3'-5'-exoribonuclease activity involved in pre-miRNA 3'-end processing OBSOLETE. Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule that contributes to forming the mature 3' end of a miRNA from a pre-miRNA. GO:0036097 obsolete pre-miRNA 3'-end processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036097 pre-miRNA 3'-end processing|miRNA 3'-end processing|microRNA 3'-end processing OBSOLETE. Any process involved in forming the mature 3' end of a miRNA from a pre-miRNA. CHEBI:75411 2-methyl-6-geranylgeranyl-1,4-benzoquinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75411 GO:0036098 male germ-line stem cell population maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036098 The process by which an organism or tissue maintains a population of male germ-line stem cells. CHEBI:75412 2,3-dimethyl-6-geranylgeranyl-1,4-benzoquinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75412 GO:0036099 female germ-line stem cell population maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036099 The process by which an organism or tissue maintains a population of female germ-line stem cells. GO:0036090 cleavage furrow ingression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036090 cleavage furrow contraction Advancement of the cleavage furrow from the outside of the cell inward towards the center of the cell. The cleavage furrow acts as a 'purse string' which draws tight to separate daughter cells during cytokinesis and partition the cytoplasm between the two daughter cells. The furrow ingresses until a cytoplasmic bridge is formed. GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036091 Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036092 phosphatidylinositol-3-phosphate anabolism|PtdIns3P biosynthesis|PI(3)P biosynthesis|phosphatidylinositol-3-phosphate synthesis|phosphatidylinositol-3-phosphate biosynthesis|phosphatidylinositol-3-phosphate formation The chemical reactions and pathways resulting in the formation of phosphatidylinositol-3-phosphate, a phosphatidylinositol monophosphate carrying the phosphate group at the 3-position. GO:0036082 extracellular phenylacetaldehyde-gated ion channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036082 ionotropic phenylacetaldehyde receptor activity Enables the transmembrane transfer of an ion by a channel that opens when extracellular phenylacetaldehyde has been bound by the channel complex or one of its constituent parts. GO:0036083 obsolete positive regulation of unsaturated fatty acid biosynthetic process by positive regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036083 OBSOLETE. Any process that activates or increases the frequency, rate or extent of unsaturated fatty acid biosynthetic process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:0036084 GDP-fucose import into endoplasmic reticulum lumen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036084 GDP-fucose import into endoplasmic reticulum|GDP-fucose transport into endoplasmic reticulum lumen|GDP-fucose transport across endoplasmic reticulum membrane The directed movement of GDP-fucose into the endoplasmic reticulum lumen. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate. GO:0036085 GDP-fucose import into Golgi lumen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036085 GDP-fucose import into Golgi|GDP-fucose transport across Golgi membrane|GDP-fucose transport into Golgi lumen The directed movement of GDP-fucose into the Golgi lumen. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate. GO:0036086 positive regulation of transcription from RNA polymerase II promoter in response to iron ion starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036086 positive regulation of transcription from RNA polymerase II promoter in response to iron deficiency Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of iron ions. GO:0036087 glutathione synthase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036087 glutathione synthetase complex A protein complex composed of two or more polypeptide subunits, and which possesses glutathione synthase activity (catalysis of the reaction: L-gamma-glutamyl-L-cysteine + ATP + glycine = ADP + glutathione + 2 H(+) + phosphate). In eukaryotes, the complex is homodimeric, in E. coli glutathione synthase exists as a tetramer, and in S. pombe the complex exists as a homodimer or a heterotetramer. GO:0036088 D-serine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036088 D-serine degradation|D-serine breakdown|D-serine catabolism The chemical reactions and pathways resulting in the breakdown of D-serine, the D-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid. GO:0036089 cleavage furrow formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036089 cleavage furrow positioning Generation of the cleavage furrow, a shallow groove in the cell surface near the old metaphase plate that marks the site of cytokinesis. This process includes the recruitment and localized activation of signals such as RhoA at the site of the future furrow to ensure that furrowing initiates at the correct site in the cell. GO:0002742 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0002742 GO:0002743 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0002743 GO:0002744 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0002744 GO:0002745 antigen processing and presentation initiated by receptor mediated uptake of antigen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002745 Antigen processing and presentation which is initiated by uptake of antigen bound to a cell surface receptor. GO:0002740 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0002740 GO:0002741 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0002741 GO:0085008 obsolete interaction with host via secreted substance released from microneme biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0085008 OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via the microneme, a small, elongated secretory organelle that forms part of the apical complex of an apicomplexan parasite. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0061040 female gonad morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061040 ovary morphogenesis The process in which a female gonad is generated and organized. GO:1905890 regulation of cellular response to very-low-density lipoprotein particle stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905890 regulation of cellular response to VLDL particle stimulus Any process that modulates the frequency, rate or extent of cellular response to very-low-density lipoprotein particle stimulus. GO:0085009 obsolete interaction with host mediated by symbiont secreted substance released from Maurer's cleft biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0085009 interaction with host mediated by symbiont secreted substance released from Maurers cleft OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via Maurer's cleft. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0061041 regulation of wound healing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061041 Any process that modulates the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury. GO:0085006 obsolete interaction with host mediated by symbiont secreted substance released from symbiont-containing vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0085006 interaction with host mediated by symbiont secreted substance released from parasitophorous vacuole OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via a symbiont-containing vacuole, a specialized sac within the host in which the symbiont resides. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0061042 vascular wound healing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061042 Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature. GO:1905891 regulation of cellular response to thapsigargin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905891 Any process that modulates the frequency, rate or extent of cellular response to thapsigargin. GO:0061043 regulation of vascular wound healing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061043 Any process that modulates the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature. GO:1905892 negative regulation of cellular response to thapsigargin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905892 down-regulation of cellular response to thapsigargin|inhibition of cellular response to thapsigargin|down regulation of cellular response to thapsigargin|downregulation of cellular response to thapsigargin Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to thapsigargin. GO:0085007 obsolete interaction with host via secreted substance released from rhoptry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0085007 OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via the rhoptry, a large, club-shaped secretory organelle that forms part of the apical complex of an apicomplexan parasite. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0061044 negative regulation of vascular wound healing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061044 Any process that decreases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature. GO:0085004 obsolete interaction with host via secreted substance released from haustorium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0085004 OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via the haustorium, a projection from a cell or tissue that penetrates the host's cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:1905893 positive regulation of cellular response to thapsigargin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905893 up-regulation of cellular response to thapsigargin|upregulation of cellular response to thapsigargin|up regulation of cellular response to thapsigargin|activation of cellular response to thapsigargin Any process that activates or increases the frequency, rate or extent of cellular response to thapsigargin. GO:0061045 negative regulation of wound healing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061045 Any process that decreases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury. GO:0085005 obsolete interaction with host via secreted substance released from invasive hyphae biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0085005 OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via invasive hyphae. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:1905894 regulation of cellular response to tunicamycin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905894 Any process that modulates the frequency, rate or extent of cellular response to tunicamycin. GO:1905884 negative regulation of triglyceride transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905884 inhibition of triacylglycerol transport|down regulation of triglyceride transport|inhibition of triglyceride transport|down regulation of triacylglycerol transport|downregulation of triacylglycerol transport|down-regulation of triglyceride transport|down-regulation of triacylglycerol transport|negative regulation of triacylglycerol transport|downregulation of triglyceride transport Any process that stops, prevents or reduces the frequency, rate or extent of triglyceride transport. GO:0085002 obsolete interaction with host mediated by secreted substance released by symbiont from symbiotic structure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0085002 OBSOLETE. An interaction with the host organism mediated by a symbiont secreted substance released by specialized structures generated in either organisms as a result of the symbiotic interaction. The term host is used for the larger (macro) of the two members of a symbiosis. GO:0061046 regulation of branching involved in lung morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061046 Any process that modulates the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. GO:0085003 obsolete interaction with host via secreted substance released from stylet biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0085003 OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via the stylet, a hollow protrusible spear-like structure in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:1905885 positive regulation of triglyceride transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905885 up-regulation of triacylglycerol transport|upregulation of triglyceride transport|upregulation of triacylglycerol transport|up-regulation of triglyceride transport|activation of triglyceride transport|up regulation of triacylglycerol transport|activation of triacylglycerol transport|positive regulation of triacylglycerol transport|up regulation of triglyceride transport Any process that activates or increases the frequency, rate or extent of triglyceride transport. GO:0061047 positive regulation of branching involved in lung morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061047 Any process that increases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. GO:1905886 chromatin remodeling involved in meiosis I biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905886 chromatin modeling involved in meiosis I|chromatin remodelling involved in meiosis I|meiosis-specific chromatin remodeling|chromatin modelling involved in meiosis I Any chromatin remodeling that is involved in meiosis I. GO:0061048 negative regulation of branching involved in lung morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061048 Any process that decreases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. GO:0085000 obsolete modification by symbiont of host morphology or physiology via protein secreted by type V secretion system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0085000 OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type V secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0061049 cell growth involved in cardiac muscle cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061049 cardiomyocyte growth|heart muscle cell growth|cardiac muscle cell hypertrophy The growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. GO:1905887 autoinducer AI-2 transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905887 autoinducer 2 transmembrane transport|AI-2 transmembrane transport|(2R,4S)-2-methyltetrahydrofuran-2,3,3,4-tetrol transmembrane transport The process in which (2R,4S)-2-methyltetrahydrofuran-2,3,3,4-tetrol (autoinducer AI-2) is transported across a membrane. AI-2 is produced by prokaryotes and is believed to play a role in quorum sensing. GO:0085001 formation of stylet for nutrient acquisition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0085001 formation by symbiont of stylet for nutrient acquisition from host The assembly of a stylet, a hollow protrusible spear-like symbiont structure projected into the host cell for the purpose of obtaining nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:1905888 negative regulation of cellular response to very-low-density lipoprotein particle stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905888 down regulation of cellular response to very-low-density lipoprotein particle stimulus|down regulation of cellular response to VLDL particle stimulus|downregulation of cellular response to very-low-density lipoprotein particle stimulus|downregulation of cellular response to VLDL particle stimulus|down-regulation of cellular response to very-low-density lipoprotein particle stimulus|down-regulation of cellular response to VLDL particle stimulus|negative regulation of cellular response to VLDL particle stimulus|inhibition of cellular response to very-low-density lipoprotein particle stimulus|inhibition of cellular response to VLDL particle stimulus Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to very-low-density lipoprotein particle stimulus. GO:1905889 positive regulation of cellular response to very-low-density lipoprotein particle stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905889 upregulation of cellular response to very-low-density lipoprotein particle stimulus|upregulation of cellular response to VLDL particle stimulus|up regulation of cellular response to very-low-density lipoprotein particle stimulus|up regulation of cellular response to VLDL particle stimulus|activation of cellular response to very-low-density lipoprotein particle stimulus|positive regulation of cellular response to VLDL particle stimulus|activation of cellular response to VLDL particle stimulus|up-regulation of cellular response to very-low-density lipoprotein particle stimulus|up-regulation of cellular response to VLDL particle stimulus Any process that activates or increases the frequency, rate or extent of cellular response to very-low-density lipoprotein particle stimulus. GO:0002746 antigen processing and presentation following pinocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002746 Antigen processing and presentation which is initiated by uptake of antigen via pinocytosis. GO:0002747 antigen processing and presentation following phagocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002747 Antigen processing and presentation which is initiated by uptake of antigen via phagocytosis. GO:0002748 antigen processing and presentation initiated by pattern recognition receptor mediated uptake of antigen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002748 antigen processing and presentation initiated by PAMP receptor mediated uptake of antigen|antigen processing and presentation initiated by PRR mediated uptake of antigen Antigen processing and presentation which is initiated by uptake of antigen bound to a cell surface pattern recognition receptor (PRR). CHEBI:51460 albaflavenone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_51460 GO:0002749 antigen processing and presentation initiated by toll-like receptor mediated phagocytosis of antigen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002749 antigen processing and presentation initiated by TLR mediated phagocytosis of antigen Antigen processing and presentation which is initiated by phagocytosis of antigen bound directly or indirectly to a cell surface toll-like receptor (TLR). GO:0002753 cytoplasmic pattern recognition receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002753 cytoplasmic pathogen receptor signaling pathway|cytoplasmic PRR signaling pathway|cytoplasmic pattern recognition receptor signalling pathway|cytoplasmic PAMP receptor signaling pathway Any series of molecular signals generated as a consequence of a cytoplasmic pattern recognition receptor (PRR) binding to one of its physiological ligands. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species. GO:0002754 intracellular endosomal pattern recognition receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002754 intracellular vesicle PAMP receptor signaling pathway|intracellular vesicle pattern recognition receptor signaling pathway|intracellular vesicle pathogen receptor signaling pathway|intracellular vesicle PRR signaling pathway|intracellular vesicle pattern recognition receptor signalling pathway Any series of molecular signals generated as a consequence of an intracellular vesicle pattern recognition receptor (PRR) binding to one of its physiological ligands. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species. GO:0002755 MyD88-dependent toll-like receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002755 MyD88-dependent TLR signaling pathway|MyD88-dependent toll-like receptor signalling pathway Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response. GO:0002756 MyD88-independent toll-like receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002756 MyD88-independent TLR signaling pathway|MyD88-independent toll-like receptor signalling pathway Any series of molecular signals generated as a consequence of binding to a toll-like receptor not relying on the MyD88 adaptor molecule. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response. GO:0002750 antigen processing and presentation following macropinocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002750 Antigen processing and presentation which is initiated by uptake of antigen via macropinocytosis. GO:0002751 antigen processing and presentation following receptor mediated endocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002751 Antigen processing and presentation which is initiated by uptake of antigen receptor-mediated endocytosis. GO:0002752 cell surface pattern recognition receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002752 cell surface pathogen receptor signaling pathway|cell surface PRR signaling pathway|cell surface pattern recognition receptor signalling pathway|cell surface PAMP receptor signaling pathway Any series of molecular signals generated as a consequence of a cell surface pattern recognition receptor (PRR) binding to one of its physiological ligands. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species. CHEBI:51458 (+)-epi-isozizaene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_51458 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061030 The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland alveolus. GO:0061031 endodermal digestive tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061031 The process in which the anatomical structures of the endodermal digestive tract are generated and organized. The endodermal digestive tract includes those portions of the digestive tract that are derived from endoderm. GO:0061032 visceral serous pericardium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061032 epicardium development The progression of the visceral serous pericardium from its formation to the mature structure. The visceral serous pericardium is the inner layer of the pericardium. GO:0061033 secretion by lung epithelial cell involved in lung growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061033 fetal lung liquid secretion The controlled release of liquid by a lung epithelial cell that contributes to an increase in size of the lung as part of its development. GO:0061034 olfactory bulb mitral cell layer development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061034 The progression of the olfactory bulb mitral cell layer over time from its initial formation until its mature state. The mitral cell layer is composed of pyramidal neurons whose cell bodies are located between the granule cell layer and the plexiform layer. GO:1905895 negative regulation of cellular response to tunicamycin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905895 down-regulation of cellular response to tunicamycin|downregulation of cellular response to tunicamycin|down regulation of cellular response to tunicamycin|inhibition of cellular response to tunicamycin Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to tunicamycin. GO:0061035 regulation of cartilage development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061035 Any process that modulates the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. GO:1905896 positive regulation of cellular response to tunicamycin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905896 up-regulation of cellular response to tunicamycin|activation of cellular response to tunicamycin|up regulation of cellular response to tunicamycin|upregulation of cellular response to tunicamycin Any process that activates or increases the frequency, rate or extent of cellular response to tunicamycin. GO:0061036 positive regulation of cartilage development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061036 Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. GO:1905897 regulation of response to endoplasmic reticulum stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905897 regulation of response to ER stress|regulation of cellular response to endoplasmic reticulum stress|regulation of ER stress response Any process that modulates the frequency, rate or extent of response to endoplasmic reticulum stress. GO:0061037 negative regulation of cartilage development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061037 Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. GO:0061038 uterus morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061038 The process in which anatomical structures of the uterus are generated and organized. GO:1905898 positive regulation of response to endoplasmic reticulum stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905898 up regulation of cellular response to endoplasmic reticulum stress|up regulation of response to ER stress|upregulation of ER stress response|activation of response to ER stress|activation of cellular response to endoplasmic reticulum stress|positive regulation of response to ER stress|positive regulation of cellular response to endoplasmic reticulum stress|up regulation of response to endoplasmic reticulum stress|activation of ER stress response|up-regulation of ER stress response|up-regulation of response to ER stress|up-regulation of cellular response to endoplasmic reticulum stress|upregulation of response to endoplasmic reticulum stress|positive regulation of ER stress response|upregulation of cellular response to endoplasmic reticulum stress|upregulation of response to ER stress|up regulation of ER stress response|activation of response to endoplasmic reticulum stress|up-regulation of response to endoplasmic reticulum stress Any process that activates or increases the frequency, rate or extent of response to endoplasmic reticulum stress. GO:1905899 regulation of smooth muscle tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905899 Any process that modulates the frequency, rate or extent of smooth muscle tissue development. GO:0061039 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0061039 CHEBI:145715 hex-3-en-1-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_145715 CHEBI:51453 (S)-carnitinium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51453 CHEBI:51454 cyclopropanes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51454 GO:0002757 immune response-activating signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002757 The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to activation or perpetuation of an immune response. GO:0002758 innate immune response-activating signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002758 defense response signalling pathway, resistance gene-dependent|defense response signaling pathway, resistance gene-independent|effector-triggered immunity|defence response signaling pathway, resistance gene-dependent|defence response signalling pathway, resistance gene-dependent|defence response signaling pathway, resistance gene-independent|effector-triggered immune signaling|defence response signalling pathway, resistance gene-independent|effector triggered immunity|defense response signaling pathway, resistance gene-dependent A series of molecular signals generated as a consequence of a pathogen or microbial effector binding to a plant 'resistance-gene' receptor to activate a plant immune response, usually plant-type hypersensitive response. GO:0002759 regulation of antimicrobial humoral response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002759 Any process that modulates the frequency, rate, or extent of an antimicrobial humoral response. GO:0099632 protein transport within plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099632 A process in which protein is transported from one region of the plasma membrane to another. GO:0002720 positive regulation of cytokine production involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002720 up regulation of cytokine production during immune response|positive regulation of cytokine secretion involved in immune response|positive regulation of cytokine production during immune response|upregulation of cytokine production during immune response|stimulation of cytokine production during immune response|activation of cytokine production during immune response|positive regulation of cytokine biosynthetic process involved in immune response|up-regulation of cytokine production during immune response Any process that activates or increases the frequency, rate, or extent of cytokine production that contributes to an immune response. GO:0099633 protein localization to postsynaptic specialization membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099633 protein localisation in postsynaptic specialization membrane A process in which a protein is transported to, or maintained in, a location within the membrane adjacent to a postsynaptic specialization (e.g. post synaptic density). GO:0002721 regulation of B cell cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002721 regulation of B-cell cytokine production|regulation of B-lymphocyte cytokine production|regulation of B lymphocyte cytokine production Any process that modulates the frequency, rate, or extent of B cell cytokine production. GO:0099630 postsynaptic neurotransmitter receptor cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099630 The process during which neurotransmitter receptors in the postsynaptic specialization membrane are recycled via the endosome. This cycle includes release from anchoring (trapping), diffusion in the synaptic membrane to the postsynaptic endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back the synaptic membrane and subsequent trapping in the postsynaptic specialization membrane. GO:0002722 negative regulation of B cell cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002722 negative regulation of B-cell cytokine production|negative regulation of B-lymphocyte cytokine production|down-regulation of B cell cytokine production|negative regulation of B lymphocyte cytokine production|downregulation of B cell cytokine production|down regulation of B cell cytokine production|inhibition of B cell cytokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell cytokine production. GO:0002723 positive regulation of B cell cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002723 upregulation of B cell cytokine production|stimulation of B cell cytokine production|positive regulation of B-cell cytokine production|activation of B cell cytokine production|up-regulation of B cell cytokine production|positive regulation of B-lymphocyte cytokine production|up regulation of B cell cytokine production|positive regulation of B lymphocyte cytokine production Any process that activates or increases the frequency, rate, or extent of B cell cytokine production. GO:0099631 postsynaptic endocytic zone cytoplasmic component biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099631 postsynaptic endocytic zone cytoplasmic component The cytoplasmic component of the postsynaptic endocytic zone. NCBITaxon:4751 Fungi organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_4751 Mycota|fungi CHEBI:51446 organic divalent group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51446 CHEBI:51447 organic univalent group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51447 GO:0061060 negative regulation of peptidoglycan recognition protein signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061060 negative regulation of peptidoglycan recognition protein signalling pathway Any process that decreases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway. GO:0061061 muscle structure development biolink:BiologicalProcess go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0061061 The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms. GO:0061062 regulation of nematode larval development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061062 Any process that modulates the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew. GO:0061063 positive regulation of nematode larval development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061063 Any process that increases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew. GO:0085028 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0085028 GO:0061064 negative regulation of nematode larval development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061064 Any process that decreases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew. GO:0061065 regulation of dauer larval development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061065 Any process that modulates the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding. CHEBI:26481 quercetin bissulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26481 GO:0085029 extracellular matrix assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0085029 The aggregation, arrangement and bonding together of the extracellular matrix. GO:0085026 tubovesicular membrane network biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0085026 TVN|TVM network A complex, symbiont-induced host-derived organelle that is comprised of multiple protein and lipid domains. GO:0061066 positive regulation of dauer larval development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061066 Any process that increases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding. CHEBI:26482 quercetin sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26482 GO:0061067 negative regulation of dauer larval development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061067 Any process that decreases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding. GO:0085027 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0085027 CHEBI:26483 quercetin trissulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26483 GO:0061068 urethra development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061068 The progression of the urethra over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body. GO:0085024 obsolete modification by symbiont of host morphology or physiology via protein secreted by Sec complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0085024 modification by symbiont of host morphology or physiology via protein secreted by the Sec secretion system OBSOLETE. The process in which an organism (symbiont) effects a change in the structure or function of its host organism, mediated by a substance secreted by the Sec complex in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0085025 obsolete modification by symbiont of host morphology or physiology via protein secreted by Tat complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0085025 modification by symbiont of host morphology or physiology via protein secreted by the Tat secretion system OBSOLETE. The process in which an organism (symbiont) effects a change in the structure or function of its host organism, mediated by a substance secreted by the Tat complex in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0061069 male urethra development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061069 The progression of the male urethra over time from its initial formation to the mature structure. The male urethra is a renal system organ that carries urine from the bladder through the penis to outside the body. GO:0085022 obsolete modification by symbiont of host morphology or physiology via protein secreted by type VI secretion system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0085022 OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type VI secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0085023 obsolete modification by symbiont of host morphology or physiology via protein secreted by type VII secretion system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0085023 OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type VII secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:26490 quinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26490 GO:0085020 protein K6-linked ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0085020 protein K6-linked polyubiquitination A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 6 of the ubiquitin monomers, is added to a protein. K6-linked ubiquitination is involved in DNA repair. GO:0085021 obsolete modification by symbiont of host morphology or physiology via protein secreted by type I secretion system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0085021 OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type I secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:51440 L-isoascorbic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51440 GO:0002728 negative regulation of natural killer cell cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002728 down regulation of natural killer cell cytokine production|downregulation of natural killer cell cytokine production|negative regulation of NK cell cytokine production|down-regulation of natural killer cell cytokine production|inhibition of natural killer cell cytokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell cytokine production. GO:0002729 positive regulation of natural killer cell cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002729 positive regulation of NK cell cytokine production|up regulation of natural killer cell cytokine production|activation of natural killer cell cytokine production|stimulation of natural killer cell cytokine production|up-regulation of natural killer cell cytokine production|upregulation of natural killer cell cytokine production Any process that activates or increases the frequency, rate, or extent of natural killer cell cytokine production. GO:0099638 endosome to plasma membrane protein transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099638 The directed movement of proteins from the endosome to the plasma membrane in transport vesicles. GO:0099639 neurotransmitter receptor transport, endosome to plasma membrane biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099639 The directed movement of neurotransmitter receptor from the endosome to the plasma membrane in transport vesicles. GO:0002724 regulation of T cell cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002724 regulation of T-cell cytokine production|regulation of T-lymphocyte cytokine production|regulation of T lymphocyte cytokine production Any process that modulates the frequency, rate, or extent of T cell cytokine production. GO:0099636 cytoplasmic streaming biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099636 Wikipedia:Cytoplasmic_streaming The directed flow of cytosol (the liquid component of the cytoplasm) and the organelles it contains. CHEBI:145707 glycosylarabinose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145707 GO:0099637 neurotransmitter receptor transport biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099637 The directed movement of neurotransmitter receptors. GO:0002725 negative regulation of T cell cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002725 down-regulation of T cell cytokine production|negative regulation of T lymphocyte cytokine production|downregulation of T cell cytokine production|down regulation of T cell cytokine production|inhibition of T cell cytokine production|negative regulation of T-cell cytokine production|negative regulation of T-lymphocyte cytokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell cytokine production. GO:0099634 postsynaptic specialization membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099634 The membrane component of the postsynaptic specialization. This is the region of the postsynaptic membrane in which the population of neurotransmitter receptors involved in synaptic transmission are concentrated. GO:0002726 positive regulation of T cell cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002726 up regulation of T cell cytokine production|positive regulation of T lymphocyte cytokine production|upregulation of T cell cytokine production|stimulation of T cell cytokine production|positive regulation of T-cell cytokine production|up-regulation of T cell cytokine production|activation of T cell cytokine production|positive regulation of T-lymphocyte cytokine production Any process that activates or increases the frequency, rate, or extent of T cell cytokine production. GO:0099635 voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099635 Positive regulation of presynaptic cytosolic calcium ion concentrations via the directed movement of calcium ions across the plasma-membrane into the cytosol via the action of voltage-gated calcium ion channels. This is the first step in synaptic transmission. GO:0002727 regulation of natural killer cell cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002727 regulation of NK cell cytokine production Any process that modulates the frequency, rate, or extent of natural killer cell cytokine production. GO:0002731 negative regulation of dendritic cell cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002731 downregulation of dendritic cell cytokine production|down regulation of dendritic cell cytokine production|inhibition of dendritic cell cytokine production|down-regulation of dendritic cell cytokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell cytokine production. GO:0099643 signal release from synapse biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099643 Any signal release from a synapse. GO:0002732 positive regulation of dendritic cell cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002732 up regulation of dendritic cell cytokine production|upregulation of dendritic cell cytokine production|stimulation of dendritic cell cytokine production|up-regulation of dendritic cell cytokine production|activation of dendritic cell cytokine production Any process that activates or increases the frequency, rate, or extent of dendritic cell cytokine production. GO:0099644 protein localization to presynaptic membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099644 protein localization in presynaptic membrane|protein localisation to presynaptic membrane|protein localisation in presynaptic membrane A process in which a protein is transported to, or maintained in, a location within a presynaptic membrane. GO:0002733 regulation of myeloid dendritic cell cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002733 Any process that modulates the frequency, rate, or extent of myeloid dendritic cell cytokine production. GO:0099641 anterograde axonal protein transport biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099641 anterograde axon cargo transport The directed movement of proteins along microtubules from the cell body toward the cell periphery in nerve cell axons. GO:0002734 negative regulation of myeloid dendritic cell cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002734 down regulation of myeloid dendritic cell cytokine production|inhibition of myeloid dendritic cell cytokine production|down-regulation of myeloid dendritic cell cytokine production|downregulation of myeloid dendritic cell cytokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell cytokine production. GO:0099642 retrograde axonal protein transport biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099642 retrograde axon cargo transport The directed movement of proteins along microtubules from the cell periphery toward the cell body in nerve cell axons. GO:0099640 axo-dendritic protein transport biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099640 axonal protein transport The directed movement of proteins along microtubules in neuron projections. NCBITaxon:4762 Oomycota organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_4762 Peronosporomycetes|oomycetes|Oomycetes GO:0002730 regulation of dendritic cell cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002730 Any process that modulates the frequency, rate, or extent of dendritic cell cytokine production. GO:0061050 regulation of cell growth involved in cardiac muscle cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061050 Any process that modulates the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. GO:0085019 formation of tubovesicular network for nutrient acquisition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0085019 formation of a symbiont- induced tubovesicular network for nutrient acquisition from host|formation by symbiont of a tubovesicular network for nutrient acquisition from host The assembly of a symbiont-induced complex organelle that comprises of multiple protein and lipid domains for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061051 Any process that increases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061052 Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. GO:0085017 entry into host cell by a symbiont-containing vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0085017 symbiont entry into host cell forming a pathogen-containing vacuole|symbiont entry into host cell forming a symbiont-containing vacuole|symbiont entry into host cell forming a parasitophorous vacuole The invasion by a symbiont of a cell of a host organism, forming a vacuole in which the symbiont resides. The vacuole membrane is formed from lipids and proteins derived from both host and symbiont. Begins when the symbiont attaches on to the host cell membrane which invaginates and deepens as the symbiont enters, and ends when the host cell membrane closes behind the newly-formed vacuole. GO:0061053 somite development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061053 The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo. GO:0085018 maintenance of symbiont-containing vacuole by host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0085018 maintenance of vacuolar integrity during bacterial infection|maintenance of parasitophorous vacuole|maintenance of pathogen-containing vacuole The process in which a host organism maintains the structure and function of a symbiont-containing vacuole. The symbiont-containing vacuole is a membrane-bounded vacuole within a host cell in which a symbiont organism resides, and can serve to reduce pathogenicity of invading symbionts by restricting them to the vacuolar compartment. GO:0061054 dermatome development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061054 The progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. GO:0085015 dormancy maintenance of symbiont in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0085015 NRP|non-replicating persistence Any process in which a dormant state is maintained by the symbiont within the host organism. GO:0061055 myotome development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061055 The progression of the myotome over time, from its formation to the mature structure. The myotome is the portion of the somite that will give rise to muscle. CHEBI:26493 quinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26493 GO:0085016 dormancy exit of symbiont in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0085016 resuscitation of symbiont Exit from dormant state, also known as resuscitation, of the symbiont within the host organism. GO:0061056 sclerotome development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061056 The progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra. GO:0061057 peptidoglycan recognition protein signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061057 Imd signalling pathway|immune deficiency signaling pathway|Imd signaling pathway|PGRP signaling pathway|immune deficiency pathway A series of molecular signals initiated by binding of peptidoglycan to a receptor and ending with regulation of a downstream cellular process. The main outcome of the Imd signaling is the production of antimicrobial peptides. GO:0085013 obsolete interaction with host via protein secreted by type VII secretion system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0085013 OBSOLETE. An interaction with the host organism mediated by a substance secreted by the symbiont organism by a type VII secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0085014 dormancy entry of symbiont in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0085014 Entry into a dormant state of the symbiont within the host organism. GO:0061058 regulation of peptidoglycan recognition protein signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061058 regulation of peptidoglycan recognition protein signalling pathway Any process that modulates the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway. GO:0085011 obsolete interaction with host via protein secreted by Sec complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0085011 interaction with host via protein secreted by Sec secretion system OBSOLETE. An interaction with the host organism mediated by a substance secreted by the symbiont organism by a Sec complex. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0061059 positive regulation of peptidoglycan recognition protein signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061059 positive regulation of peptidoglycan recognition protein signalling pathway Any process that increases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway. GO:0085012 obsolete interaction with host via protein secreted by Tat complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0085012 interaction with host via protein secreted by Tat secretion system OBSOLETE. An interaction with the host organism mediated by a substance secreted by the symbiont organism by a Tat complex. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0085010 obsolete interaction with host mediated by secreted substance entering host via endocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0085010 OBSOLETE. An interaction with the host organism mediated by a secreted substance from the symbiont entering host cells via endocytosis of the substance. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:9638 torulene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_9638 GO:0002739 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0002739 GO:0002735 positive regulation of myeloid dendritic cell cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002735 upregulation of myeloid dendritic cell cytokine production|stimulation of myeloid dendritic cell cytokine production|activation of myeloid dendritic cell cytokine production|up-regulation of myeloid dendritic cell cytokine production|up regulation of myeloid dendritic cell cytokine production Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell cytokine production. GO:0002736 regulation of plasmacytoid dendritic cell cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002736 Any process that modulates the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production. GO:0002737 negative regulation of plasmacytoid dendritic cell cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002737 downregulation of plasmacytoid dendritic cell cytokine production|down-regulation of plasmacytoid dendritic cell cytokine production|inhibition of plasmacytoid dendritic cell cytokine production|down regulation of plasmacytoid dendritic cell cytokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production. GO:0099645 neurotransmitter receptor localization to postsynaptic specialization membrane biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099645 neurotransmitter receptor localisation in postsynaptic specialization membrane A process in which a neurotransmitter is transported to, or maintained in, a location within the membrane adjacent to a postsynaptic specialization (e.g. postsynaptic density). GO:0002738 positive regulation of plasmacytoid dendritic cell cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002738 up regulation of plasmacytoid dendritic cell cytokine production|activation of plasmacytoid dendritic cell cytokine production|stimulation of plasmacytoid dendritic cell cytokine production|up-regulation of plasmacytoid dendritic cell cytokine production|upregulation of plasmacytoid dendritic cell cytokine production Any process that activates or increases the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production. GO:0099646 neurotransmitter receptor transport, plasma membrane to endosome biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099646 Vesicle-mediated transport of a neurotransmitter receptor vesicle from the plasma membrane to the endosome. GO:0099699 integral component of synaptic membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099699 The component of the synaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0002700 regulation of production of molecular mediator of immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002700 Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response. GO:0002701 negative regulation of production of molecular mediator of immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002701 down regulation of production of molecular mediator of immune response|downregulation of production of molecular mediator of immune response|down-regulation of production of molecular mediator of immune response|inhibition of production of molecular mediator of immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of the production of molecular mediator of immune response. CHEBI:51422 organodiyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51422 GO:0061080 right horn of sinus venosus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061080 The progression of the right horn of the sinus venosus from its formation to the mature structure. GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061081 positive regulation of myeloid cell cytokine production involved in immune response Any process that modulates the rate, frequency, or extent of the production of a cytokine that contributes to the immune response. CHEBI:26469 quaternary nitrogen compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26469 GO:0061082 myeloid leukocyte cytokine production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0061082 Any process that contributes to cytokine production by a myeloid cell. CHEBI:26463 pyruvate family amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26463 GO:0061083 regulation of protein refolding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061083 Any process that regulates the rate, frequency, or extent of protein refolding. Protein refolding is the process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones. GO:0061084 negative regulation of protein refolding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061084 Any process that decreases the rate, frequency, or extent of protein refolding. Protein refolding is the process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones. GO:0061085 regulation of histone H3-K27 methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061085 Any process that modulates the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone. GO:0061086 negative regulation of histone H3-K27 methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061086 Any process that decreases the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone. GO:0061087 positive regulation of histone H3-K27 methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061087 Any process that increases the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone. GO:0061088 regulation of sequestering of zinc ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061088 Any process that modulates the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system. GO:0061089 negative regulation of sequestering of zinc ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061089 Any process that decreases the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system. CHEBI:26461 pyrroloquinoline cofactor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26461 GO:0085044 disassembly by symbiont of host cuticle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0085044 degradation of host cuticle|catabolism of host cuticle The process in which a symbiont organism effects a breakdown of the host organism cuticle. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0085042 periarbuscular membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0085042 A host-derived membrane surrounding the symbiont arbuscule during symbiosis. GO:0085040 obsolete extra-invasive hyphal space biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0085040 OBSOLETE. The space between the symbiont plasma membrane and the extra-invasive hyphal membrane. GO:0085041 arbuscule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0085041 Highly branched symbiont haustoria within host root cortex cells, responsible for nutrient exchange. GO:0002706 regulation of lymphocyte mediated immunity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002706 Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity. CHEBI:9688 trichodermin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_9688 GO:0002707 negative regulation of lymphocyte mediated immunity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002707 down-regulation of lymphocyte mediated immunity|downregulation of lymphocyte mediated immunity|down regulation of lymphocyte mediated immunity|inhibition of lymphocyte mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte mediated immunity. GO:0002708 positive regulation of lymphocyte mediated immunity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002708 stimulation of lymphocyte mediated immunity|up-regulation of lymphocyte mediated immunity|activation of lymphocyte mediated immunity|up regulation of lymphocyte mediated immunity|upregulation of lymphocyte mediated immunity Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity. GO:0002709 regulation of T cell mediated immunity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002709 regulation of T-lymphocyte mediated immunity|regulation of T lymphocyte mediated immunity|regulation of T-cell mediated immunity Any process that modulates the frequency, rate, or extent of T cell mediated immunity. GO:0002702 positive regulation of production of molecular mediator of immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002702 upregulation of production of molecular mediator of immune response|up regulation of production of molecular mediator of immune response|activation of production of molecular mediator of immune response|stimulation of production of molecular mediator of immune response|up-regulation of production of molecular mediator of immune response Any process that activates or increases the frequency, rate, or extent of the production of molecular mediator of immune response. GO:0002703 regulation of leukocyte mediated immunity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002703 regulation of leucocyte mediated immunity|regulation of immune cell mediated immunity Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity. GO:0002704 negative regulation of leukocyte mediated immunity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002704 down-regulation of leukocyte mediated immunity|inhibition of leukocyte mediated immunity|negative regulation of immune cell mediated immunity|down regulation of leukocyte mediated immunity|downregulation of leukocyte mediated immunity|negative regulation of leucocyte mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte mediated immunity. GO:0002705 positive regulation of leukocyte mediated immunity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002705 positive regulation of immune cell mediated immunity|up-regulation of leukocyte mediated immunity|upregulation of leukocyte mediated immunity|positive regulation of leucocyte mediated immunity|up regulation of leukocyte mediated immunity|activation of leukocyte mediated immunity|stimulation of leukocyte mediated immunity Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity. GO:0002710 negative regulation of T cell mediated immunity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002710 negative regulation of T-lymphocyte mediated immunity|down-regulation of T cell mediated immunity|negative regulation of T lymphocyte mediated immunity|downregulation of T cell mediated immunity|down regulation of T cell mediated immunity|inhibition of T cell mediated immunity|negative regulation of T-cell mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated immunity. GO:0002711 positive regulation of T cell mediated immunity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002711 stimulation of T cell mediated immunity|positive regulation of T-cell mediated immunity|up-regulation of T cell mediated immunity|activation of T cell mediated immunity|positive regulation of T-lymphocyte mediated immunity|up regulation of T cell mediated immunity|positive regulation of T lymphocyte mediated immunity|upregulation of T cell mediated immunity Any process that activates or increases the frequency, rate, or extent of T cell mediated immunity. GO:0002712 regulation of B cell mediated immunity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002712 regulation of B lymphocyte mediated immunity|regulation of B-cell mediated immunity|regulation of B-lymphocyte mediated immunity Any process that modulates the frequency, rate, or extent of B cell mediated immunity. GO:0061070 female urethra development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061070 The progression of the female urethra over time from its initial formation to the mature structure. The female urethra is a renal system organ that carries urine from the bladder to outside the body, exiting above the vaginal opening. GO:0061071 urethra epithelium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061071 The progression of the urethra epithelium over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body. The epithelium is the tubular, planar layer of cells through which the urine passes. GO:0061072 iris morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061072 The process in which the iris is generated and organized. The iris is an anatomical structure in the eye whose opening forms the pupil. The iris is responsible for controlling the diameter and size of the pupil and the amount of light reaching the retina. GO:0061073 ciliary body morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061073 The process in which the ciliary body generated and organized. The ciliary body is the circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes. GO:0061074 regulation of neural retina development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061074 Any process that modulates the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells. GO:0085039 hyphal membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0085039 extra-invasive hyphal membrane A host-derived membrane surrounding the symbiont hypha during infection. GO:0061075 positive regulation of neural retina development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061075 Any process that increases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells. GO:0061076 negative regulation of neural retina development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061076 Any process that decreases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells. GO:0061077 chaperone-mediated protein folding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061077 The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone. GO:0085037 extrahaustorial membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0085037 The membrane surrounding the symbiont haustorium during symbiosis, derived from the host plasma membrane. GO:0061078 positive regulation of prostaglandin secretion involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061078 positive regulation of prostaglandin secretion during immune response Any process that activates or increases the frequency, rate or extent of the regulated release of a prostaglandin from a cell and contributes to the immune response. GO:0085035 haustorium biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0085035 A projection from a cell or tissue that penetrates the host's cell wall and invaginates the host cell membrane. GO:0061079 left horn of sinus venosus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061079 The progression of the left horn of the sinus venosus from its initial formation to the mature structure. GO:0085036 extrahaustorial matrix biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0085036 The space between the symbiont plasma membrane and the extrahaustorial membrane of the host. GO:0085033 induction by symbiont of host I-kappaB kinase/NF-kappaB cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0085033 up-regulation by symbiont of host I-kappaB kinase/NF-kappaB cascade|stimulation by symbiont of host I-kappaB kinase/NF-kappaB cascade|activation by symbiont of host I-kappaB kinase/NF-kappaB cascade|positive regulation by symbiont of host I-kappaB kinase/NF-kappaB cascade|positive regulation by symbiont of nuclear factor kappa-light-chain-enhancer of activated B cells mediated signal transduction pathway|up regulation by symbiont of host I-kappaB kinase/NF-kappaB cascade|upregulation by symbiont of host I-kappaB kinase/NF-kappaB cascade|positive regulation by symbiont of host NF-kappaB-mediated signal transduction pathway|induction by symbiont of host I-kappaB kinase/NF-kappaB cascade Any process that activates or increases the frequency, rate or extent of host NF-kappaB-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0085034 suppression by symbiont of host I-kappaB kinase/NF-kappaB cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0085034 negative regulation by symbiont of host I-kappaB kinase/NF-kappaB cascade Any process that stops, prevents, or reduces the frequency, rate or extent of host NF-kappaB-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0085031 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0085031 GO:0085032 modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0085032 modulation by symbiont of host NF-kappaB-mediated signal transduction pathway Any process in which an organism modulates the frequency, rate or extent of host NF-kappaB-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0085030 symbiotic process benefiting host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0085030 mutualism A process carried out by symbiont gene products that enables a symbiotic interaction with a host organism, that is beneficial to the host organism. GO:0002717 positive regulation of natural killer cell mediated immunity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002717 upregulation of natural killer cell mediated immunity|positive regulation of NK cell mediated immunity|up regulation of natural killer cell mediated immunity|positive regulation of natural killer cell activity|activation of natural killer cell mediated immunity|stimulation of natural killer cell mediated immunity|positive regulation of NK cell activity|up-regulation of natural killer cell mediated immunity Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated immunity. GO:0002718 regulation of cytokine production involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002718 regulation of cytokine biosynthetic process involved in immune response|regulation of cytokine secretion involved in immune response|regulation of cytokine production during immune response Any process that modulates the frequency, rate, or extent of cytokine production that contributes to an immune response. GO:0002719 negative regulation of cytokine production involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002719 inhibition of cytokine production during immune response|down-regulation of cytokine production during immune response|negative regulation of cytokine biosynthetic process involved in immune response|negative regulation of cytokine secretion involved in immune response|downregulation of cytokine production during immune response|negative regulation of cytokine production during immune response|down regulation of cytokine production during immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine production contributing to an immune response. GO:0002713 negative regulation of B cell mediated immunity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002713 downregulation of B cell mediated immunity|down regulation of B cell mediated immunity|inhibition of B cell mediated immunity|negative regulation of B-cell mediated immunity|negative regulation of B-lymphocyte mediated immunity|down-regulation of B cell mediated immunity|negative regulation of B lymphocyte mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell mediated immunity. GO:0002714 positive regulation of B cell mediated immunity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002714 positive regulation of B lymphocyte mediated immunity|upregulation of B cell mediated immunity|positive regulation of B-cell mediated immunity|stimulation of B cell mediated immunity|up-regulation of B cell mediated immunity|activation of B cell mediated immunity|positive regulation of B-lymphocyte mediated immunity|up regulation of B cell mediated immunity Any process that activates or increases the frequency, rate, or extent of B cell mediated immunity. GO:0002715 regulation of natural killer cell mediated immunity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002715 regulation of NK cell mediated immunity|regulation of natural killer cell activity Any process that modulates the frequency, rate, or extent of natural killer cell mediated immunity. GO:0002716 negative regulation of natural killer cell mediated immunity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002716 down regulation of natural killer cell mediated immunity|negative regulation of natural killer cell activity|downregulation of natural killer cell mediated immunity|negative regulation of NK cell mediated immunity|negative regulation of NK cell activity|down-regulation of natural killer cell mediated immunity|inhibition of natural killer cell mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated immunity. CHEBI:26444 pyrimidine ribonucleoside triphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26444 CHEBI:26446 pyrimidine ribonucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26446 CHEBI:26447 pyrimidinemonocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26447 CHEBI:26440 pyrimidine nucleoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26440 CHEBI:26441 pyrimidine nucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26441 CHEBI:26442 pyrimidine ribonucleoside diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26442 CHEBI:26443 pyrimidine ribonucleoside monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26443 UBERON:0008000 sesamoid bone of pes biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008000 sesamoid bone of foot A sesamoid bone that is part of a pes. UBERON:0008001 irregular bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008001 os irregulare|os irregulare The irregular bones are bones which, from their peculiar form, cannot be grouped as long bone, short bone, flat bone or sesamoid bone. Irregular bones serve various purposes in the body, such as protection of nervous tissue, affording multiple anchor points for skeletal muscle attachment (as with the sacrum), and maintaining pharynx and trachea support, and tongue attachment (such as the hyoid bone). They consist of cancellous tissue enclosed within a thin layer of compact bone. The irregular bones are: the vertebrC&, sacrum, coccyx, temporal, sphenoid, ethmoid, zygomatic, maxilla, mandible, palatine, inferior nasal concha, and hyoid. CHEBI:9661 triacetin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_9661 CHEBI:26455 pyrroles biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26455 GO:0061090 positive regulation of sequestering of zinc ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061090 Any process that increases the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system. CHEBI:26456 pyrrolidine alkaloid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26456 GO:0061091 regulation of phospholipid translocation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061091 Any process that modulates the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer. CHEBI:26457 1-pyrrolinecarboxylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26457 GO:0061092 positive regulation of phospholipid translocation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061092 Any process that increases the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer. GO:0061093 negative regulation of phospholipid translocation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061093 Any process that decreases the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer. GO:0061094 regulation of turning behavior involved in mating biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061094 Any process that modulates the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail. CHEBI:26452 pyrrolecarboxylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26452 GO:0061095 positive regulation of turning behavior involved in mating biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061095 Any process that increases the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail. CHEBI:26454 pyrrolecarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26454 GO:0061096 negative regulation of turning behavior involved in mating biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061096 Any process that decreases the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail. GO:0061097 regulation of protein tyrosine kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061097 Any process that modulates the rate, frequency, or extent of protein tyrosine kinase activity. GO:0061098 positive regulation of protein tyrosine kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061098 Any process that increases the rate, frequency, or extent of protein tyrosine kinase activity. GO:0061099 negative regulation of protein tyrosine kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061099 Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity. GO:0051632 negative regulation of acetylcholine uptake biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051632 down regulation of acetylcholine uptake|negative regulation of acetylcholine import|down-regulation of acetylcholine uptake|downregulation of acetylcholine uptake Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of acetylcholine into a cell. GO:0051633 positive regulation of acetylcholine uptake biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051633 upregulation of acetylcholine uptake|positive regulation of acetylcholine import|stimulation of acetylcholine uptake|activation of acetylcholine uptake|up-regulation of acetylcholine uptake|up regulation of acetylcholine uptake Any process that activates or increases the frequency, rate or extent of the directed movement of acetylcholine into a cell. GO:0051630 acetylcholine uptake biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051630 acetylcholine import The directed movement of acetylcholine into a cell, typically presynaptic neurons or glial cells. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues. GO:0075601 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075601 GO:0051631 regulation of acetylcholine uptake biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051631 regulation of acetylcholine import Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter acetylcholine into a cell. GO:0051636 obsolete Gram-negative bacterial cell surface binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051636 Gram-negative bacterium binding|Gram-negative bacterial cell surface binding|Gram-negative bacterial binding|Gram-negative bacterium cell surface binding|binding to Gram-negative bacterium OBSOLETE. Interacting selectively and non-covalently with any component on the surface of a Gram-negative bacterial cell. GO:0051637 obsolete Gram-positive bacterial cell surface binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051637 Gram-positive bacterium binding|Gram-positive bacterial cell surface binding|Gram-positive bacterial binding|binding to Gram-positive bacterium|Gram-positive bacterium cell surface binding OBSOLETE. Interacting selectively and non-covalently with any component on the surface of a Gram-positive bacterium. GO:0051634 inhibition of acetylcholine uptake biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051634 inhibition of acetylcholine import Any process that prevents the activation of the directed movement of acetylcholine into a cell. GO:0051635 obsolete bacterial cell surface binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051635 binding to bacterium|bacterium cell surface binding|bacterium binding|bacterial cell surface binding|bacterial binding OBSOLETE. Interacting selectively and non-covalently with any component on the surface of a bacterial cell. GO:0075606 transport of viral material towards nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075606 VZ:990 cytoplasmic inwards viral transport|viral genome transport to host cell nucleus|transport of viral material to nucleus The directed movement of a virus, or part of a virus, towards the host cell nucleus. The process begins after viral entry, and ends when the viral material is at the nuclear membrane. GO:0051638 barbed-end actin filament uncapping biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051638 barbed-end F-actin uncapping|plus end actin filament uncapping|plus end F-actin uncapping|barbed end F-actin uncapping|plus-end F-actin uncapping|plus-end actin filament uncapping|barbed end actin filament uncapping The removal of capping protein from the barbed (or plus) end of actin filaments to free the ends for addition, exchange or removal of further actin subunits. GO:0051639 actin filament network formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051639 actin gel formation|actin gel biosynthesis The assembly of a network of actin filaments; actin filaments on different axes and with differing orientations are crosslinked together to form a mesh of filaments. GO:1905800 negative regulation of intraciliary retrograde transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905800 down regulation of intraciliary retrograde transport|downregulation of intraciliary retrograde transport|down regulation of intraflagellar retrograde transport|downregulation of intraflagellar retrograde transport|down-regulation of intraciliary retrograde transport|down-regulation of intraflagellar retrograde transport|negative regulation of intraflagellar retrograde transport|inhibition of intraciliary retrograde transport|inhibition of intraflagellar retrograde transport Any process that stops, prevents or reduces the frequency, rate or extent of intraciliary retrograde transport. GO:1905801 positive regulation of intraciliary retrograde transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905801 upregulation of intraciliary retrograde transport|upregulation of intraflagellar retrograde transport|up regulation of intraciliary retrograde transport|activation of intraciliary retrograde transport|up regulation of intraflagellar retrograde transport|activation of intraflagellar retrograde transport|positive regulation of intraflagellar retrograde transport|up-regulation of intraciliary retrograde transport|up-regulation of intraflagellar retrograde transport Any process that activates or increases the frequency, rate or extent of intraciliary retrograde transport. GO:1905802 regulation of cellular response to manganese ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905802 regulation of cellular response to manganese Any process that modulates the frequency, rate or extent of cellular response to manganese ion. GO:1905803 negative regulation of cellular response to manganese ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905803 down-regulation of cellular response to manganese ion|down-regulation of cellular response to manganese|negative regulation of cellular response to manganese|downregulation of cellular response to manganese ion|down regulation of cellular response to manganese ion|inhibition of cellular response to manganese ion|downregulation of cellular response to manganese|down regulation of cellular response to manganese|inhibition of cellular response to manganese Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to manganese ion. GO:1905804 positive regulation of cellular response to manganese ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905804 up-regulation of cellular response to manganese ion|activation of cellular response to manganese ion|up-regulation of cellular response to manganese|activation of cellular response to manganese|up regulation of cellular response to manganese ion|positive regulation of cellular response to manganese|up regulation of cellular response to manganese|upregulation of cellular response to manganese ion|upregulation of cellular response to manganese Any process that activates or increases the frequency, rate or extent of cellular response to manganese ion. GO:1905805 excitatory synapse pruning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905805 synapse clearance|synapse disassembly|synapse removal|synapse elimination The disaggregation of an excitatory synapse into its constituent components. CHEBI:75397 N-acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75397 GO:1905806 regulation of synapse pruning biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_1905806 regulation of synapse disassembly|regulation of synapse elimination|regulation of synapse clearance|regulation of synapse removal Any process that modulates the frequency, rate or extent of synapse pruning. GO:1905807 negative regulation of synapse pruning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905807 regulation of synapse disassembly|down regulation of synapse disassembly|downregulation of synapse disassembly|regulation of synapse removal|regulation of synapse elimination|down-regulation of synapse disassembly|inhibition of synapse disassembly|regulation of synapse clearance Any process that stops, prevents or reduces the frequency, rate or extent of synapse pruning. GO:1905808 positive regulation of synapse pruning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905808 upregulation of synapse disassembly|regulation of synapse disassembly|regulation of synapse removal|up regulation of synapse disassembly|activation of synapse disassembly|regulation of synapse elimination|up-regulation of synapse disassembly|regulation of synapse clearance Any process that activates or increases the frequency, rate or extent of synapse pruning. GO:1905809 negative regulation of synapse organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905809 inhibition of synapse organization and biogenesis|downregulation of synapse morphogenesis|downregulation of synapse development|down-regulation of synapse organisation|negative regulation of synapse organisation|down regulation of synapse organization and biogenesis|down-regulation of synapse organization|down-regulation of synapse morphogenesis|negative regulation of synapse morphogenesis|down-regulation of synapse development|negative regulation of synapse development|downregulation of synapse organisation|downregulation of synapse organization and biogenesis|down regulation of synapse organisation|inhibition of synapse organisation|inhibition of synapse development|downregulation of synapse organization|negative regulation of synapse organization and biogenesis|down-regulation of synapse organization and biogenesis|inhibition of synapse morphogenesis|down regulation of synapse organization|inhibition of synapse organization|down regulation of synapse morphogenesis|down regulation of synapse development Any process that stops, prevents or reduces the frequency, rate or extent of synapse organization. GO:0051643 endoplasmic reticulum localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051643 establishment and maintenance of ER localization|ER localization|endoplasmic reticulum localisation Any process in which endoplasmic reticulum is transported to, and/or maintained in, a specific location within the cell. GO:0051644 plastid localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051644 establishment and maintenance of plastid localization|plastid localisation Any process in which a plastid is transported to, and/or maintained in, a specific location within the cell. GO:0051641 cellular localization biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0051641 establishment and maintenance of cellular localization|single-organism cellular localization|intracellular localization|localization within cell|establishment and maintenance of localization in cell or cell membrane|cellular localisation|single organism cellular localization A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane. GO:0051642 centrosome localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051642 centrosome localisation|establishment and maintenance of centrosome localization Any process in which a centrosome is transported to, and/or maintained in, a specific location within the cell. GO:0051647 nucleus localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051647 nucleus localisation|cell nucleus localization|localization of nucleus|establishment and maintenance of nucleus localization Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell. GO:0051648 vesicle localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051648 vesicle localisation|cytoplasmic vesicle localization|establishment and maintenance of vesicle localization Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location. GO:0051645 Golgi localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051645 establishment and maintenance of Golgi localization|Golgi body localization|Golgi localisation|Golgi apparatus localization Any process in which the Golgi is transported to, and/or maintained in, a specific location within the cell. GO:0051646 mitochondrion localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051646 establishment and maintenance of mitochondrion localization|localization of mitochondria|mitochondrion localisation|localization of mitochondrion|mitochondria localization|establishment and maintenance of mitochondria localization|mitochondrial localization Any process in which a mitochondrion or mitochondria are transported to, and/or maintained in, a specific location within the cell. GO:0051649 establishment of localization in cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051649 establishment of localisation in cell|establishment of intracellular localization|positioning within cell|establishment of localization within cell|establishment of cellular localization Any process, occuring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation. GO:1905810 regulation of excitatory synapse pruning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905810 regulation of synapse clearance|regulation of synapse disassembly|regulation of synapse removal|regulation of synapse elimination Any process that modulates the frequency, rate or extent of excitatory synapse pruning. GO:1905811 negative regulation of excitatory synapse pruning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905811 downregulation of excitatory synapse disassembly|down regulation of excitatory synapse disassembly|regulation of synapse clearance|inhibition of excitatory synapse disassembly|regulation of synapse disassembly|regulation of synapse removal|down-regulation of excitatory synapse disassembly|regulation of synapse elimination Any process that stops, prevents or reduces the frequency, rate or extent of excitatory synapse pruning. GO:1905812 regulation of motor neuron axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905812 regulation of motor axon pathfinding|regulation of motoneuron axon guidance|regulation of motor axon guidance Any process that modulates the frequency, rate or extent of motor neuron axon guidance. GO:1905813 negative regulation of motor neuron axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905813 downregulation of motor axon pathfinding|negative regulation of motor axon guidance|down-regulation of motor axon guidance|down regulation of motor axon pathfinding|downregulation of motor neuron axon guidance|inhibition of motor axon pathfinding|inhibition of motor axon guidance|down regulation of motor neuron axon guidance|inhibition of motor neuron axon guidance|negative regulation of motoneuron axon guidance|down-regulation of motoneuron axon guidance|downregulation of motoneuron axon guidance|down regulation of motor axon guidance|negative regulation of motor axon pathfinding|down-regulation of motor axon pathfinding|down regulation of motoneuron axon guidance|inhibition of motoneuron axon guidance|downregulation of motor axon guidance|down-regulation of motor neuron axon guidance Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron axon guidance. GO:1905814 positive regulation of motor neuron axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905814 up regulation of motor neuron axon guidance|up-regulation of motoneuron axon guidance|activation of motoneuron axon guidance|upregulation of motor axon pathfinding|up-regulation of motor axon guidance|upregulation of motor neuron axon guidance|positive regulation of motoneuron axon guidance|up-regulation of motor axon pathfinding|up regulation of motoneuron axon guidance|upregulation of motor axon guidance|activation of motor axon pathfinding|up-regulation of motor neuron axon guidance|activation of motor neuron axon guidance|upregulation of motoneuron axon guidance|up regulation of motor axon guidance|positive regulation of motor axon pathfinding|positive regulation of motor axon guidance|up regulation of motor axon pathfinding|activation of motor axon guidance Any process that activates or increases the frequency, rate or extent of motor neuron axon guidance. GO:1905815 regulation of dorsal/ventral axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905815 regulation of dorsoventral axon guidance|regulation of dorsal/ventral axon pathfinding|regulation of dorsal-ventral axon guidance Any process that modulates the frequency, rate or extent of dorsal/ventral axon guidance. GO:1905816 negative regulation of dorsal/ventral axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905816 downregulation of dorsoventral axon guidance|down regulation of dorsal/ventral axon pathfinding|down regulation of dorsoventral axon guidance|inhibition of dorsoventral axon guidance|downregulation of dorsal/ventral axon pathfinding|negative regulation of dorsal-ventral axon guidance|down-regulation of dorsal-ventral axon guidance|down-regulation of dorsal/ventral axon guidance|negative regulation of dorsal/ventral axon pathfinding|down-regulation of dorsal/ventral axon pathfinding|downregulation of dorsal-ventral axon guidance|downregulation of dorsal/ventral axon guidance|down regulation of dorsal-ventral axon guidance|inhibition of dorsal/ventral axon pathfinding|negative regulation of dorsoventral axon guidance|down-regulation of dorsoventral axon guidance|down regulation of dorsal/ventral axon guidance|inhibition of dorsal-ventral axon guidance|inhibition of dorsal/ventral axon guidance Any process that stops, prevents or reduces the frequency, rate or extent of dorsal/ventral axon guidance. GO:1905817 positive regulation of dorsal/ventral axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905817 upregulation of dorsal/ventral axon pathfinding|up-regulation of dorsal-ventral axon guidance|activation of dorsal-ventral axon guidance|up-regulation of dorsal/ventral axon guidance|activation of dorsal/ventral axon guidance|upregulation of dorsoventral axon guidance|up regulation of dorsal/ventral axon pathfinding|positive regulation of dorsal/ventral axon pathfinding|activation of dorsal/ventral axon pathfinding|positive regulation of dorsal-ventral axon guidance|up regulation of dorsal-ventral axon guidance|up-regulation of dorsoventral axon guidance|activation of dorsoventral axon guidance|up regulation of dorsal/ventral axon guidance|up-regulation of dorsal/ventral axon pathfinding|upregulation of dorsal-ventral axon guidance|positive regulation of dorsoventral axon guidance|upregulation of dorsal/ventral axon guidance|up regulation of dorsoventral axon guidance Any process that activates or increases the frequency, rate or extent of dorsal/ventral axon guidance. GO:1905818 regulation of chromosome separation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905818 regulation of rDNA separation|regulation of chromatid release Any process that modulates the frequency, rate or extent of chromosome separation. GO:1905819 negative regulation of chromosome separation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905819 negative regulation of chromatid release|down-regulation of chromatid release|down regulation of chromosome separation|inhibition of rDNA separation|downregulation of chromosome separation|down regulation of rDNA separation|inhibition of chromatid release|downregulation of rDNA separation|down-regulation of chromosome separation|down regulation of chromatid release|inhibition of chromosome separation|negative regulation of rDNA separation|down-regulation of rDNA separation|downregulation of chromatid release Any process that stops, prevents or reduces the frequency, rate or extent of chromosome separation. GO:0051640 organelle localization biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0051640 establishment and maintenance of organelle localization|organelle localisation Any process in which an organelle is transported to, and/or maintained in, a specific location. GO:0051654 establishment of mitochondrion localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051654 establishment of mitochondrion localisation|mitochondria positioning|mitochondrial migration|establishment of mitochondria localization|mitochondrion positioning The directed movement of the mitochondrion to a specific location. GO:0002687 positive regulation of leukocyte migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002687 positive regulation of leucocyte migration|up regulation of leukocyte migration|activation of leukocyte migration|stimulation of leukocyte migration|positive regulation of immune cell migration|up-regulation of leukocyte migration|upregulation of leukocyte migration Any process that activates or increases the frequency, rate, or extent of leukocyte migration. GO:0051655 maintenance of vesicle location biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051655 maintenance of vesicle localization Any process in which a vesicle is maintained in a specific location within a cell and prevented from moving elsewhere. GO:0002688 regulation of leukocyte chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002688 regulation of leucocyte chemotaxis|regulation of immune cell chemotaxis Any process that modulates the frequency, rate, or extent of leukocyte chemotaxis. GO:0002689 negative regulation of leukocyte chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002689 negative regulation of leucocyte chemotaxis|downregulation of leukocyte chemotaxis|down regulation of leukocyte chemotaxis|inhibition of leukocyte chemotaxis|negative regulation of immune cell chemotaxis|down-regulation of leukocyte chemotaxis Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte chemotaxis. GO:0051652 maintenance of chromosome location biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051652 maintenance of chromosome localization Any process in which a chromosome is maintained in a specific location within a cell and prevented from moving elsewhere. GO:0051653 spindle localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051653 establishment and maintenance of spindle localization|spindle localisation Any process in which is the spindle is transported to, and/or maintained in, a specific location. GO:0002683 negative regulation of immune system process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002683 down-regulation of immune system process|inhibition of immune system process|down regulation of immune system process|downregulation of immune system process Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process. GO:0051658 maintenance of nucleus location biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051658 maintenance of nucleus localization|maintenance of cell nucleus location Any process in which the nucleus is maintained in a specific location within a cell and prevented from moving elsewhere. GO:0002684 positive regulation of immune system process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002684 activation of immune system process|stimulation of immune system process|up-regulation of immune system process|upregulation of immune system process|up regulation of immune system process Any process that activates or increases the frequency, rate, or extent of an immune system process. GO:0051659 maintenance of mitochondrion location biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051659 maintenance of mitochondrion localization|maintenance of mitochondria localization Any process in which a mitochondrion is maintained in a specific location within a cell and prevented from moving elsewhere. GO:0002685 regulation of leukocyte migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002685 regulation of immune cell migration|regulation of leucocyte migration Any process that modulates the frequency, rate, or extent of leukocyte migration. GO:0051656 establishment of organelle localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051656 establishment of organelle localisation The directed movement of an organelle to a specific location. GO:0002686 negative regulation of leukocyte migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002686 downregulation of leukocyte migration|negative regulation of leucocyte migration|down-regulation of leukocyte migration|inhibition of leukocyte migration|negative regulation of immune cell migration|down regulation of leukocyte migration Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte migration. GO:0051657 maintenance of organelle location biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051657 maintenance of organelle localization Any process in which an organelle is maintained in a specific location within a cell and prevented from moving elsewhere. GO:0002680 pro-T cell lineage commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002680 pro-T lymphocyte lineage commitment|pro-T cell fate commitment|pro-T lymphocyte fate commitment The process in which a lymphoid progenitor cell becomes committed to becoming a pro-T cell. GO:0002681 somatic recombination of T cell receptor gene segments biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002681 somatic recombination of TCR gene segments The process in which T cell receptor genes are formed through recombination of the germline genetic elements, also known as T cell receptor gene segments. GO:0002682 regulation of immune system process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002682 Any process that modulates the frequency, rate, or extent of an immune system process. GO:1905820 positive regulation of chromosome separation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905820 activation of rDNA separation|up regulation of chromatid release|positive regulation of chromatid release|up-regulation of rDNA separation|upregulation of chromosome separation|activation of chromatid release|upregulation of rDNA separation|up-regulation of chromatid release|up regulation of chromosome separation|activation of chromosome separation|up regulation of rDNA separation|upregulation of chromatid release|positive regulation of rDNA separation|up-regulation of chromosome separation Any process that activates or increases the frequency, rate or extent of chromosome separation. GO:1905821 positive regulation of chromosome condensation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905821 upregulation of chromosome condensation|activation of eukaryotic chromosome condensation|up-regulation of eukaryotic chromosome condensation|up regulation of nuclear chromosome condensation|activation of nuclear chromosome condensation|positive regulation of nuclear chromosome condensation|up regulation of chromosome condensation|activation of chromosome condensation|positive regulation of eukaryotic chromosome condensation|up regulation of eukaryotic chromosome condensation|up-regulation of nuclear chromosome condensation|up-regulation of chromosome condensation|upregulation of eukaryotic chromosome condensation|upregulation of nuclear chromosome condensation Any process that activates or increases the frequency, rate or extent of chromosome condensation. GO:1905822 regulation of mitotic sister chromatid arm separation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905822 Any process that modulates the frequency, rate or extent of mitotic sister chromatid arm separation. GO:1905823 negative regulation of mitotic sister chromatid arm separation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905823 down-regulation of mitotic sister chromatid arm separation|inhibition of mitotic sister chromatid arm separation|down regulation of mitotic sister chromatid arm separation|downregulation of mitotic sister chromatid arm separation Any process that stops, prevents or reduces the frequency, rate or extent of mitotic sister chromatid arm separation. GO:1905824 positive regulation of mitotic sister chromatid arm separation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905824 activation of mitotic sister chromatid arm separation|up-regulation of mitotic sister chromatid arm separation|upregulation of mitotic sister chromatid arm separation|up regulation of mitotic sister chromatid arm separation Any process that activates or increases the frequency, rate or extent of mitotic sister chromatid arm separation. GO:1905825 regulation of selenocysteine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905825 regulation of selenocysteine metabolism Any process that modulates the frequency, rate or extent of selenocysteine metabolic process. GO:1905826 negative regulation of selenocysteine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905826 inhibition of selenocysteine metabolism|down-regulation of selenocysteine metabolic process|down regulation of selenocysteine metabolism|downregulation of selenocysteine metabolic process|downregulation of selenocysteine metabolism|down regulation of selenocysteine metabolic process|inhibition of selenocysteine metabolic process|down-regulation of selenocysteine metabolism|negative regulation of selenocysteine metabolism Any process that stops, prevents or reduces the frequency, rate or extent of selenocysteine metabolic process. GO:1905827 positive regulation of selenocysteine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905827 up-regulation of selenocysteine metabolism|up-regulation of selenocysteine metabolic process|activation of selenocysteine metabolic process|upregulation of selenocysteine metabolism|up regulation of selenocysteine metabolic process|up regulation of selenocysteine metabolism|activation of selenocysteine metabolism|positive regulation of selenocysteine metabolism|upregulation of selenocysteine metabolic process Any process that activates or increases the frequency, rate or extent of selenocysteine metabolic process. GO:1905828 regulation of prostaglandin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905828 regulation of prostaglandin catabolism|regulation of prostaglandin degradation|regulation of prostaglandin breakdown Any process that modulates the frequency, rate or extent of prostaglandin catabolic process. GO:1905829 negative regulation of prostaglandin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905829 downregulation of prostaglandin catabolic process|down-regulation of prostaglandin degradation|negative regulation of prostaglandin degradation|negative regulation of prostaglandin catabolism|down-regulation of prostaglandin catabolism|down-regulation of prostaglandin breakdown|negative regulation of prostaglandin breakdown|inhibition of prostaglandin degradation|down-regulation of prostaglandin catabolic process|inhibition of prostaglandin breakdown|downregulation of prostaglandin catabolism|down regulation of prostaglandin catabolism|inhibition of prostaglandin catabolic process|inhibition of prostaglandin catabolism|down regulation of prostaglandin degradation|downregulation of prostaglandin degradation|down regulation of prostaglandin breakdown|downregulation of prostaglandin breakdown|down regulation of prostaglandin catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of prostaglandin catabolic process. GO:0051650 establishment of vesicle localization biolink:BiologicalProcess go-plus goslim_aspergillus http://purl.obolibrary.org/obo/GO_0051650 establishment of vesicle localisation The directed movement of a vesicle to a specific location. GO:0051651 maintenance of location in cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051651 maintenance of intracellular localization|maintenance of localization within cell|cellular retention|intracellular retention|cellular storage|intracellular storage|intracellular sequestering|sequestering within cell|cellular sequestering|retention within cell|maintenance of cellular localization|maintenance of localization in cell|storage within cell Any process in which a substance or cellular entity, such as a protein complex or organelle, is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere. GO:0002698 negative regulation of immune effector process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002698 down regulation of immune effector process|downregulation of immune effector process|down-regulation of immune effector process|inhibition of immune effector process Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process. GO:0051665 membrane raft localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051665 establishment and maintenance of membrane raft localization|membrane raft localisation|lipid raft localization Any process in which membrane rafts are transported to, or maintained in, a specific location. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. GO:0002699 positive regulation of immune effector process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002699 upregulation of immune effector process|up regulation of immune effector process|activation of immune effector process|stimulation of immune effector process|up-regulation of immune effector process Any process that activates or increases the frequency, rate, or extent of an immune effector process. GO:0051666 actin cortical patch localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051666 actin cortical patch localisation|establishment and maintenance of actin cortical patch localization Any process in which actin cortical patches are transported to, or maintained in, a specific location. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells. GO:0051663 oocyte nucleus localization involved in oocyte dorsal/ventral axis specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051663 oocyte nucleus localization during oocyte axis determination|oocyte nucleus localization involved in oocyte dorsal-ventral axis specification|oocyte nucleus localisation involved in oocyte dorsal/ventral axis specification|oocyte axis determination, oocyte nucleus localization|establishment and maintenance of oocyte nucleus localization during oocyte axis determination|oocyte nucleus localization involved in oocyte dorsal/ventral axis determination|oocyte nucleus localization involved in oocyte dorsoventral axis specification The directed movement of the nucleus to a specific location within a cell during the establishment and maintenance of the dorsal/ventral axis of the oocyte. GO:0051664 nuclear pore localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051664 establishment and maintenance of nuclear pore localization|positioning of nuclear pores|nuclear pore distribution|nuclear pore localisation Any process in which nuclear pores are transported to, or maintained in, a specific location. GO:0051669 fructan beta-fructosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051669 MetaCyc:3.2.1.80-RXN|EC:3.2.1.80 fructanase activity|exo-beta-D-fructosidase activity|fructan exohydrolase activity|fructan b-fructosidase activity|beta-D-fructan fructohydrolase activity|polysaccharide beta-fructofuranosidase activity|exo-beta-fructosidase activity Catalysis of the hydrolysis of terminal, non-reducing 2,1- and 2,6-linked beta-D-fructofuranose residues in fructans. GO:0002694 regulation of leukocyte activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002694 regulation of immune cell activation|regulation of leucocyte activation Any process that modulates the frequency, rate, or extent of leukocyte activation. CHEBI:99 (-)-maackiain biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_99 GO:0002695 negative regulation of leukocyte activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002695 down-regulation of leukocyte activation|negative regulation of leucocyte activation|downregulation of leukocyte activation|down regulation of leukocyte activation|inhibition of leukocyte activation|negative regulation of immune cell activation Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation. GO:0002696 positive regulation of leukocyte activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002696 positive regulation of immune cell activation|up regulation of leukocyte activation|positive regulation of leucocyte activation|upregulation of leukocyte activation|stimulation of leukocyte activation|up-regulation of leukocyte activation|activation of leukocyte activation Any process that activates or increases the frequency, rate, or extent of leukocyte activation. GO:0051667 establishment of plastid localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051667 establishment of plastid localisation The directed movement of a plastid to a specific location in the cell. GO:0051668 localization within membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051668 positioning within membrane|localisation within membrane|establishment and maintenance of position in membrane|localization to membrane|establishment and maintenance of localization in membrane Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane. GO:0002697 regulation of immune effector process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002697 Any process that modulates the frequency, rate, or extent of an immune effector process. GO:0002690 positive regulation of leukocyte chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002690 positive regulation of immune cell chemotaxis|up regulation of leukocyte chemotaxis|positive regulation of leucocyte chemotaxis|upregulation of leukocyte chemotaxis|stimulation of leukocyte chemotaxis|up-regulation of leukocyte chemotaxis|activation of leukocyte chemotaxis Any process that activates or increases the frequency, rate, or extent of leukocyte chemotaxis. GO:0002691 regulation of cellular extravasation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002691 Any process that modulates the frequency, rate, or extent of cellular extravasation. GO:0002692 negative regulation of cellular extravasation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002692 down-regulation of cellular extravasation|downregulation of cellular extravasation|down regulation of cellular extravasation|inhibition of cellular extravasation Any process that stops, prevents, or reduces the frequency, rate, or extent of cellular extravasation. GO:0002693 positive regulation of cellular extravasation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002693 stimulation of cellular extravasation|up-regulation of cellular extravasation|activation of cellular extravasation|up regulation of cellular extravasation|upregulation of cellular extravasation Any process that activates or increases the frequency, rate, or extent of cellular extravasation. CHEBI:98 (S)-linalool biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_98 GO:1905830 positive regulation of prostaglandin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905830 upregulation of prostaglandin catabolic process|up regulation of prostaglandin degradation|positive regulation of prostaglandin degradation|activation of prostaglandin degradation|up-regulation of prostaglandin catabolism|activation of prostaglandin catabolism|up regulation of prostaglandin breakdown|activation of prostaglandin breakdown|positive regulation of prostaglandin breakdown|up regulation of prostaglandin catabolic process|activation of prostaglandin catabolic process|positive regulation of prostaglandin catabolism|up-regulation of prostaglandin degradation|up regulation of prostaglandin catabolism|up-regulation of prostaglandin breakdown|up-regulation of prostaglandin catabolic process|upregulation of prostaglandin degradation|upregulation of prostaglandin catabolism|upregulation of prostaglandin breakdown Any process that activates or increases the frequency, rate or extent of prostaglandin catabolic process. GO:1905831 negative regulation of spindle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905831 downregulation of spindle formation|down regulation of bipolar spindle formation|down-regulation of spindle biosynthesis|negative regulation of spindle biosynthesis|downregulation of bipolar spindle biosynthesis|down-regulation of spindle formation|downregulation of bipolar spindle formation|negative regulation of spindle formation|down regulation of bipolar spindle biosynthesis|inhibition of bipolar spindle biosynthesis|down-regulation of spindle assembly|inhibition of spindle formation|downregulation of spindle biosynthesis|negative regulation of bipolar spindle formation|down-regulation of bipolar spindle formation|down regulation of spindle biosynthesis|inhibition of spindle biosynthesis|downregulation of spindle assembly|inhibition of bipolar spindle formation|down regulation of spindle assembly|down regulation of spindle formation|inhibition of spindle assembly|negative regulation of bipolar spindle biosynthesis|down-regulation of bipolar spindle biosynthesis Any process that stops, prevents or reduces the frequency, rate or extent of spindle assembly. GO:1905832 positive regulation of spindle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905832 up-regulation of spindle biosynthesis|activation of spindle biosynthesis|upregulation of bipolar spindle formation|up regulation of spindle formation|positive regulation of bipolar spindle biosynthesis|up regulation of bipolar spindle biosynthesis|activation of spindle formation|positive regulation of spindle formation|up-regulation of spindle assembly|activation of spindle assembly|up regulation of bipolar spindle formation|positive regulation of spindle biosynthesis|up regulation of spindle biosynthesis|activation of bipolar spindle formation|positive regulation of bipolar spindle formation|upregulation of bipolar spindle biosynthesis|up-regulation of spindle formation|up regulation of spindle assembly|upregulation of spindle biosynthesis|up-regulation of bipolar spindle biosynthesis|up-regulation of bipolar spindle formation|activation of bipolar spindle biosynthesis|upregulation of spindle formation|upregulation of spindle assembly Any process that activates or increases the frequency, rate or extent of spindle assembly. GO:1905833 negative regulation of microtubule nucleation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905833 down-regulation of microtubule nucleation|downregulation of microtubule nucleation|down regulation of microtubule nucleation|inhibition of microtubule nucleation Any process that stops, prevents or reduces the frequency, rate or extent of microtubule nucleation. GO:1905834 response to pyrimidine ribonucleotide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905834 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pyrimidine ribonucleotide stimulus. GO:1905835 cellular response to pyrimidine ribonucleotide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905835 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pyrimidine ribonucleotide stimulus. GO:1905836 response to triterpenoid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905836 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triterpenoid stimulus. GO:1905837 cellular response to triterpenoid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905837 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triterpenoid stimulus. GO:1905838 regulation of telomeric D-loop disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905838 Any process that modulates the frequency, rate or extent of telomeric D-loop disassembly. GO:1905839 negative regulation of telomeric D-loop disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905839 downregulation of telomeric D-loop disassembly|down regulation of telomeric D-loop disassembly|inhibition of telomeric D-loop disassembly|down-regulation of telomeric D-loop disassembly Any process that stops, prevents or reduces the frequency, rate or extent of telomeric D-loop disassembly. GO:0051661 maintenance of centrosome location biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051661 maintenance of centrosome localization Any process in which a centrosome is maintained in a specific location within a cell and prevented from moving elsewhere. GO:0051662 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051662 GO:0051660 establishment of centrosome localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051660 establishment of centrosome localisation|centrosome positioning The directed movement of the centrosome to a specific location. GO:0002665 negative regulation of T cell tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002665 negative regulation of T-lymphocyte tolerance induction|down-regulation of T cell tolerance induction|negative regulation of T lymphocyte tolerance induction|downregulation of T cell tolerance induction|down regulation of T cell tolerance induction|inhibition of T cell tolerance induction|negative regulation of T-cell tolerance induction Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell tolerance induction. GO:0099610 action potential initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099610 action potential firing|action potential triggering The initiating cycle of an action potential. In vertebrate neurons this typically occurs at an axon hillock. Not all initiated axon potentials propagate. GO:0051676 pullulan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051676 pullulan metabolism The chemical reactions and pathways involving pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages. GO:0051677 pullulan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051677 The chemical reactions and pathways resulting in the formation of pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages. GO:0002666 positive regulation of T cell tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002666 stimulation of T cell tolerance induction|positive regulation of T-cell tolerance induction|activation of T cell tolerance induction|up-regulation of T cell tolerance induction|positive regulation of T-lymphocyte tolerance induction|up regulation of T cell tolerance induction|positive regulation of T lymphocyte tolerance induction|upregulation of T cell tolerance induction Any process that activates or increases the frequency, rate, or extent of T cell tolerance induction. GO:0099611 regulation of action potential firing threshold biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099611 Any process that regulates the potential at which an axon potential is triggered. GO:0051674 localization of cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051674 establishment and maintenance of localization of cell|establishment and maintenance of cell localization|localisation of cell|cell localization Any process in which a cell is transported to, and/or maintained in, a specific location. GO:0002667 regulation of T cell anergy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002667 regulation of T-lymphocyte anergy|regulation of T-cell anergy|regulation of T lymphocyte anergy Any process that modulates the frequency, rate, or extent of T cell anergy. GO:0051675 isopullulanase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051675 EC:3.2.1.57|MetaCyc:3.2.1.57-RXN pullulan 4-glucanohydrolase (isopanose-forming) activity Catalysis of the hydrolysis of pullulan to isopanose (6-alpha-maltosylglucose). GO:0002668 negative regulation of T cell anergy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002668 negative regulation of T lymphocyte anergy|down-regulation of T cell anergy|inhibition of T cell anergy|negative regulation of T-lymphocyte anergy|negative regulation of T-cell anergy|down regulation of T cell anergy|downregulation of T cell anergy Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell anergy. GO:0002661 regulation of B cell tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002661 regulation of B lymphocyte tolerance induction|regulation of B-cell tolerance induction|regulation of B-lymphocyte tolerance induction Any process that modulates the frequency, rate, or extent of B cell tolerance induction. CHEBI:51389 calixpyrroles biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51389 GO:0002662 negative regulation of B cell tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002662 downregulation of B cell tolerance induction|down regulation of B cell tolerance induction|inhibition of B cell tolerance induction|negative regulation of B-cell tolerance induction|negative regulation of B-lymphocyte tolerance induction|down-regulation of B cell tolerance induction|negative regulation of B lymphocyte tolerance induction Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell tolerance induction. GO:0002663 positive regulation of B cell tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002663 positive regulation of B lymphocyte tolerance induction|upregulation of B cell tolerance induction|positive regulation of B-cell tolerance induction|stimulation of B cell tolerance induction|up-regulation of B cell tolerance induction|activation of B cell tolerance induction|positive regulation of B-lymphocyte tolerance induction|up regulation of B cell tolerance induction Any process that activates or increases the frequency, rate, or extent of B cell tolerance induction. GO:0051678 pullulan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051678 The chemical reactions and pathways resulting in the breakdown of pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages. GO:0051679 6-alpha-maltosylglucose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051679 6-alpha-maltosylglucose metabolism|isopanose metabolic process|isopanose metabolism The chemical reactions and pathways involving 6-alpha-maltosylglucose, also known as isopanose. GO:0002664 regulation of T cell tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002664 regulation of T-cell tolerance induction|regulation of T-lymphocyte tolerance induction|regulation of T lymphocyte tolerance induction Any process that modulates the frequency, rate, or extent of T cell tolerance induction. GO:0002660 positive regulation of peripheral tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002660 up regulation of peripheral tolerance induction|upregulation of peripheral tolerance induction|stimulation of peripheral tolerance induction|activation of peripheral tolerance induction|up-regulation of peripheral tolerance induction Any process that activates or increases the frequency, rate, or extent of peripheral tolerance induction. GO:0061000 negative regulation of dendritic spine development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061000 Any process that decreases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure. GO:0061001 regulation of dendritic spine morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061001 Any process that modulates the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission. GO:1905850 positive regulation of forward locomotion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905850 upregulation of forward locomotion|up-regulation of forward locomotion|activation of forward locomotion|up regulation of forward locomotion Any process that activates or increases the frequency, rate or extent of forward locomotion. GO:0061002 negative regulation of dendritic spine morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061002 Any process that decreases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission. GO:1905840 positive regulation of telomeric D-loop disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905840 up regulation of telomeric D-loop disassembly|upregulation of telomeric D-loop disassembly|up-regulation of telomeric D-loop disassembly|activation of telomeric D-loop disassembly Any process that activates or increases the frequency, rate or extent of telomeric D-loop disassembly. GO:1905841 response to oxidopamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905841 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxidopamine stimulus. GO:0061003 positive regulation of dendritic spine morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061003 Any process that increases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission. GO:1905842 cellular response to oxidopamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905842 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxidopamine stimulus. GO:0061004 pattern specification involved in kidney development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061004 pattern formation involved in kidney development|kidney pattern specification|kidney pattern formation Any developmental process that results in the creation of defined areas or spaces within the kidney to which cells respond and eventually are instructed to differentiate. GO:1905843 regulation of cellular response to gamma radiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905843 regulation of cellular response to gamma ray|regulation of cellular response to gamma-ray photon Any process that modulates the frequency, rate or extent of cellular response to gamma radiation. GO:0061005 cell differentiation involved in kidney development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061005 The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the kidney as it progresses from its formation to the mature state. GO:1905844 negative regulation of cellular response to gamma radiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905844 downregulation of cellular response to gamma ray|inhibition of cellular response to gamma-ray photon|down regulation of cellular response to gamma ray|downregulation of cellular response to gamma radiation|down regulation of cellular response to gamma-ray photon|down regulation of cellular response to gamma radiation|inhibition of cellular response to gamma radiation|downregulation of cellular response to gamma-ray photon|inhibition of cellular response to gamma ray|down-regulation of cellular response to gamma-ray photon|negative regulation of cellular response to gamma-ray photon|down-regulation of cellular response to gamma ray|negative regulation of cellular response to gamma ray|down-regulation of cellular response to gamma radiation Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to gamma radiation. GO:0061006 regulation of cell proliferation involved in kidney morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061006 Any process that modulates the frequency, rate or extent of cell proliferation that contributes to the shaping of the kidney. GO:1905845 positive regulation of cellular response to gamma radiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905845 up regulation of cellular response to gamma radiation|upregulation of cellular response to gamma-ray photon|upregulation of cellular response to gamma ray|upregulation of cellular response to gamma radiation|up regulation of cellular response to gamma-ray photon|up-regulation of cellular response to gamma ray|positive regulation of cellular response to gamma-ray photon|activation of cellular response to gamma radiation|up-regulation of cellular response to gamma radiation|activation of cellular response to gamma-ray photon|activation of cellular response to gamma ray|positive regulation of cellular response to gamma ray|up-regulation of cellular response to gamma-ray photon|up regulation of cellular response to gamma ray Any process that activates or increases the frequency, rate or extent of cellular response to gamma radiation. GO:0061007 hepaticobiliary system process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061007 hepatobiliary system process An system process carried out by any of the organs or tissues of the hepaticobiliary system. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins. GO:0061008 hepaticobiliary system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061008 hepatobiliary system development The progression of the hepaticobiliary system over time, from its formation to the mature structure. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins. GO:1905846 regulation of cellular response to oxidopamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905846 Any process that modulates the frequency, rate or extent of cellular response to oxidopamine. GO:1905847 negative regulation of cellular response to oxidopamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905847 downregulation of cellular response to oxidopamine|down regulation of cellular response to oxidopamine|inhibition of cellular response to oxidopamine|down-regulation of cellular response to oxidopamine Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to oxidopamine. GO:0061009 common bile duct development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061009 extrahepatic bile duct development|CBD development|bile duct development|EHBD development The progression of the common bile duct over time, from its formation to the mature structure. The common bile duct is formed from the joining of the common hepatic duct running from the liver, and the cystic duct running from the gall bladder. The common bile duct transports bile from the liver and gall bladder to the intestine. GO:1905848 positive regulation of cellular response to oxidopamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905848 upregulation of cellular response to oxidopamine|up-regulation of cellular response to oxidopamine|activation of cellular response to oxidopamine|up regulation of cellular response to oxidopamine Any process that activates or increases the frequency, rate or extent of cellular response to oxidopamine. GO:0099618 UDP-glucuronic acid dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0099618 RHEA:24702|EC:1.1.1.305 UDP-GlcUA decarboxylase activity Catalysis of the reaction: UDP-glucuronate + NAD+ = UDP-beta-L-threo-pentapyranos-4-ulose + CO2 + NADH + H+. GO:1905849 negative regulation of forward locomotion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905849 down-regulation of forward locomotion|downregulation of forward locomotion|down regulation of forward locomotion|inhibition of forward locomotion Any process that stops, prevents or reduces the frequency, rate or extent of forward locomotion. GO:0099619 UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0099619 EC:2.1.2.13|RHEA:24706 UDP-L-Ara4N formyltransferase activity|10-formyltetrahydrofolate:UDP-4-amino-4-deoxy-beta-L-arabinose N-formyltransferase activity|ArnAFT activity Catalysis of the reaction: 10-formyltetrahydrofolate + UDP-4-amino-4-deoxy-beta-L-arabinopyranose = 5,6,7,8-tetrahydrofolate + UDP-4-deoxy-4-formamido-beta-L-arabinopyranose. CHEBI:51387 calix(hetero)arene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51387 GO:0099616 extrinsic component of matrix side of mitochondrial inner membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0099616 The component of the matrix side of the mitochondrial inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:0099617 matrix side of mitochondrial inner membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0099617 The side (leaflet) of the mitochondrial inner membrane that faces the matrix. GO:0002669 positive regulation of T cell anergy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002669 positive regulation of T lymphocyte anergy|up regulation of T cell anergy|activation of T cell anergy|stimulation of T cell anergy|positive regulation of T-lymphocyte anergy|up-regulation of T cell anergy|positive regulation of T-cell anergy|upregulation of T cell anergy Any process that activates or increases the frequency, rate, or extent of T cell anergy. GO:0051672 catabolism by organism of cell wall peptidoglycan in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051672 cell wall catabolism in other organism|cell wall catabolic process in other organism|cell wall peptidoglycan catabolic process in another organism|catabolic process of cell wall peptidoglycans of other organism|catabolism of cell wall peptidoglycans of other organism The chemical reactions and pathways resulting in the breakdown of the cell wall peptidoglycans of another organism. GO:0099614 protein localization to spore cell wall biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099614 protein targeting to spore cell wall A process in which a protein is transported, tethered to or otherwise maintained in a spore cell wall. GO:0051673 membrane disruption in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051673 cytolysis, by membrane disruption, in other organism|membrane disruption in another organism The disruption of the membranes of another organism, leading to damage to its cells and possibly death of that organism. GO:0099615 (D)-2-hydroxyglutarate-pyruvate transhydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0099615 D-2HG-pyruvate transhydrogenase activity|R-2-hydroxyglutarate alpha-pyruvate transhydrogenase activity Catalysis of the reaction: (R)-2-hydroxyglutarate + pyruvate = alpha-ketoglutarate + D-lactate, with FAD functioning as an intermediate hydrogen acceptor. GO:0099612 protein localization to axon biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099612 A process in which a protein is transported to or maintained in a location within an axon. GO:0051670 inulinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051670 MetaCyc:3.2.1.7-RXN|EC:3.2.1.7 indoinulinase activity|2,1-beta-D-fructan fructanohydrolase activity|exoinulinase activity|inulase activity|endo-inulinase activity Catalysis of the endohydrolysis of 2,1-beta-D-fructosidic linkages in inulin. GO:0051671 induction of autolysin activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051671 positive regulation of autolysin activity in another organism|induction of autolytic activity in other organism|activation of autolysis in other organism|activation of autolytic activity in other organism|activation of autolysin activity in another organism|induction of autolysis in other organism|induction of autolysin activity in another organism Any process in which an organism initiates the activity of the inactive enzyme autolysin in another organism. The autolysin enzyme belongs to, and is active in, the other organism. GO:0099613 protein localization to cell wall biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099613 The process of directing proteins towards the cell-wall. CHEBI:51384 D-ascorbic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51384 GO:0099621 undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0099621 MetaCyc:RXN0-3521|EC:2.4.2.53|RHEA:27722 undecaprenyl-phosphate Ara4FN transferase activity|undecaprenyl phosphate-L-Ara4FN transferase activity|Ara4FN transferase activity Catalysis of the reaction: UDP-4-deoxy-4-formamido-beta-L-arabinopyranose + ditrans,octacis-undecaprenyl phosphate = UDP + 4-deoxy-4-formamido-alpha-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate. GO:0051687 maintenance of spindle location biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051687 maintenance of spindle localization Any process in which the spindle is maintained in a specific location within a cell and prevented from moving elsewhere. GO:0002676 regulation of chronic inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002676 Any process that modulates the frequency, rate, or extent of a chronic inflammatory response. GO:0002677 negative regulation of chronic inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002677 inhibition of chronic inflammatory response|down regulation of chronic inflammatory response|downregulation of chronic inflammatory response|down-regulation of chronic inflammatory response Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response. GO:0099622 cardiac muscle cell membrane repolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099622 The process in which ions are transported across the plasma membrane of a cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential. GO:0051688 maintenance of plastid location biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051688 maintenance of plastid localization Any process in which a plastid is maintained in a specific location within a cell and prevented from moving elsewhere. GO:0002678 positive regulation of chronic inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002678 up-regulation of chronic inflammatory response|upregulation of chronic inflammatory response|up regulation of chronic inflammatory response|activation of chronic inflammatory response|stimulation of chronic inflammatory response Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response. GO:0051685 maintenance of ER location biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051685 maintenance of ER localization|maintenance of endoplasmic reticulum localization Any process in which the endoplasmic reticulum is maintained in a specific location within a cell and prevented from moving elsewhere. GO:0051686 establishment of ER localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051686 establishment of ER localisation|establishment of endoplasmic reticulum localization The directed movement of the endoplasmic reticulum to a specific location. GO:0099620 UDP-4-amino-4-deoxy-L-arabinose aminotransferase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0099620 EC:2.6.1.87|RHEA:24710 UDP-L-Ara4N transaminase|UDP-4-amino-4-deoxy-beta-L-arabinose:2-oxoglutarate aminotransferase|UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase|UDP-Ara4O aminotransferase|UDP-4-amino-4-deoxy-L-arabinose---oxoglutarate aminotransferase Catalysis of the reaction: UDP-4-amino-4-deoxy-beta-L-arabinopyranose + 2-oxoglutarate = UDP-beta-L-threo-pentapyranos-4-ulose + L-glutamate. GO:0002679 respiratory burst involved in defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002679 A phase of elevated metabolic activity, during which oxygen consumption increases made as part of a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. GO:0002672 positive regulation of B cell anergy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002672 activation of B cell anergy|stimulation of B cell anergy|positive regulation of B-lymphocyte anergy|up-regulation of B cell anergy|positive regulation of B-cell anergy|upregulation of B cell anergy|positive regulation of B lymphocyte anergy|up regulation of B cell anergy Any process that activates or increases the frequency, rate, or extent of B cell anergy. GO:0002673 regulation of acute inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002673 Any process that modulates the frequency, rate, or extent of an acute inflammatory response. GO:0002674 negative regulation of acute inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002674 inhibition of acute inflammatory response|down regulation of acute inflammatory response|downregulation of acute inflammatory response|down-regulation of acute inflammatory response Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response. GO:0051689 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051689 GO:0002675 positive regulation of acute inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002675 up-regulation of acute inflammatory response|upregulation of acute inflammatory response|up regulation of acute inflammatory response|activation of acute inflammatory response|stimulation of acute inflammatory response Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response. GO:0002670 regulation of B cell anergy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002670 regulation of B-lymphocyte anergy|regulation of B-cell anergy|regulation of B lymphocyte anergy Any process that modulates the frequency, rate, or extent of B cell anergy. GO:0002671 negative regulation of B cell anergy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002671 negative regulation of B lymphocyte anergy|down-regulation of B cell anergy|inhibition of B cell anergy|negative regulation of B-lymphocyte anergy|negative regulation of B-cell anergy|down regulation of B cell anergy|downregulation of B cell anergy Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell anergy. GO:1905860 positive regulation of heparan sulfate proteoglycan binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905860 positive regulation of heparin proteoglycan binding|up regulation of heparin proteoglycan binding|upregulation of heparan sulfate proteoglycan binding|upregulation of heparin proteoglycan binding|up-regulation of heparan sulfate proteoglycan binding|activation of heparan sulfate proteoglycan binding|up-regulation of heparin proteoglycan binding|up regulation of heparan sulfate proteoglycan binding|activation of heparin proteoglycan binding Any process that activates or increases the frequency, rate or extent of heparan sulfate proteoglycan binding. GO:1905861 intranuclear rod assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905861 intranuclear rod formation|intranuclear actin rod assembly|intranuclear actin rod formation The aggregation, arrangement and bonding together of a set of components to form an intranuclear rod. GO:1905851 negative regulation of backward locomotion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905851 down regulation of backward locomotion|downregulation of backward locomotion|down-regulation of backward locomotion|inhibition of backward locomotion Any process that stops, prevents or reduces the frequency, rate or extent of backward locomotion. GO:1905852 positive regulation of backward locomotion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905852 upregulation of backward locomotion|up regulation of backward locomotion|activation of backward locomotion|up-regulation of backward locomotion Any process that activates or increases the frequency, rate or extent of backward locomotion. GO:1905853 regulation of heparan sulfate binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905853 Any process that modulates the frequency, rate or extent of heparan sulfate binding. GO:1905854 negative regulation of heparan sulfate binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905854 down-regulation of heparan sulfate binding|inhibition of heparan sulfate binding|down regulation of heparan sulfate binding|downregulation of heparan sulfate binding Any process that stops, prevents or reduces the frequency, rate or extent of heparan sulfate binding. GO:1905855 positive regulation of heparan sulfate binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905855 up regulation of heparan sulfate binding|activation of heparan sulfate binding|up-regulation of heparan sulfate binding|upregulation of heparan sulfate binding Any process that activates or increases the frequency, rate or extent of heparan sulfate binding. GO:1905856 negative regulation of pentose-phosphate shunt biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905856 Any process that stops, prevents or reduces the frequency, rate or extent of pentose-phosphate shunt. GO:1905857 positive regulation of pentose-phosphate shunt biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905857 Any process that activates or increases the frequency, rate or extent of pentose-phosphate shunt. GO:1905858 regulation of heparan sulfate proteoglycan binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905858 regulation of heparin proteoglycan binding Any process that modulates the frequency, rate or extent of heparan sulfate proteoglycan binding. GO:1905859 negative regulation of heparan sulfate proteoglycan binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905859 down regulation of heparin proteoglycan binding|inhibition of heparin proteoglycan binding|down-regulation of heparan sulfate proteoglycan binding|negative regulation of heparin proteoglycan binding|down-regulation of heparin proteoglycan binding|downregulation of heparan sulfate proteoglycan binding|down regulation of heparan sulfate proteoglycan binding|inhibition of heparan sulfate proteoglycan binding|downregulation of heparin proteoglycan binding Any process that stops, prevents or reduces the frequency, rate or extent of heparan sulfate proteoglycan binding. GO:0099629 postsynaptic specialization of symmetric synapse biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099629 postsynaptic density of inhibitory synapse A network of proteins within and adjacent to the postsynaptic membrane of a symmetric synapse, consisting of anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components that spatially and functionally organize the neurotransmitter receptors at the synapse. This structure is not as thick or electron dense as the postsynaptic densities found in asymmetric synapses. CHEBI:51374 GABA agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51374 GO:0051680 6-alpha-maltosylglucose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051680 isopanose biosynthetic process|isopanose biosynthesis The chemical reactions and pathways resulting in the formation of 6-alpha-maltosylglucose, also known as isopanose. GO:0099627 neurotransmitter receptor cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099627 The process during which neurotransmitter receptors, anchored in some region of the synaptic membrane, are recycled via the endosome. This cycle includes release from anchoring, diffusion in the synaptic membrane to an endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back the synaptic membrane and subsequent anchoring (trapping). GO:0099628 neurotransmitter receptor diffusion trapping biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099628 The process by which diffusing neurotransmitter receptor becomes trapped in region of the plasma membrane. GO:0051683 establishment of Golgi localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051683 establishment of Golgi body localization|establishment of Golgi localisation|establishment of Golgi apparatus localization The directed movement of the Golgi to a specific location. GO:0099625 ventricular cardiac muscle cell membrane repolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099625 The process in which ions are transported across the plasma membrane of a ventricular cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential. GO:0051684 maintenance of Golgi location biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051684 maintenance of Golgi body localization|maintenance of Golgi localization|maintenance of Golgi apparatus localization Any process in which the Golgi is maintained in a specific location within a cell and prevented from moving elsewhere. CHEBI:51371 muscle relaxant biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51371 GO:0099626 voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099626 voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels Regulation of presynaptic cytosolic calcium ion concentrations via the action of voltage-gated calcium ion channels. GO:0099623 regulation of cardiac muscle cell membrane repolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099623 regulation of cardiac muscle cell repolarization|heart repolarization|regulation of cardiomyocyte membrane repolarization Any process that modulates the establishment or extent of a change in membrane potential in the polarizing direction towards the resting potential in a cardiomyocyte. CHEBI:51372 neuromuscular agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51372 GO:0051681 6-alpha-maltosylglucose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051681 isopanose catabolism|isopanose catabolic process The chemical reactions and pathways resulting in the breakdown of 6-alpha-maltosylglucose, also known as isopanose. CHEBI:51373 GABA agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51373 GO:0051682 galactomannan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051682 The chemical reactions and pathways resulting in the breakdown of galactomannan, a polysaccharide composed of D-galactosyl and D-mannosyl. The mannosyl units form the backbone structure (a linear main chain) with the D-galactosyl as single side units. GO:0099624 atrial cardiac muscle cell membrane repolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099624 The process in which ions are transported across the plasma membrane of an atrial cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential. GO:0051698 saccharopine oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051698 SAX activity Catalysis of the reaction: L-saccharopine + O2 = L-2-aminoadipic 6-semialdehyde + L-glutamate + H2O2. GO:0002643 regulation of tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002643 Any process that modulates the frequency, rate, or extent of tolerance induction. GO:0002644 negative regulation of tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002644 inhibition of tolerance induction|down regulation of tolerance induction|downregulation of tolerance induction|down-regulation of tolerance induction Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction. GO:0051699 proline oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051699 RHEA:26124|MetaCyc:RXN-821 Catalysis of the reaction: L-proline + O2 + H2O = L-delta1-pyrroline-5-carboxylate + H2O2. GO:0051696 pointed-end actin filament uncapping biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051696 minus-end actin filament uncapping|minus end F-actin uncapping|pointed end F-actin uncapping|pointed end actin filament uncapping|minus end actin filament uncapping|minus-end F-actin uncapping|pointed-end F-actin uncapping The removal of capping protein from the pointed (or minus) end of actin filaments to free the ends for addition, exchange or removal of further actin subunits. GO:0002645 positive regulation of tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002645 up-regulation of tolerance induction|upregulation of tolerance induction|up regulation of tolerance induction|activation of tolerance induction|stimulation of tolerance induction Any process that activates or increases the frequency, rate, or extent of tolerance induction. GO:0051697 protein delipidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051697 The breakage of covalent bonds to detach lipid groups from a protein. GO:0002646 regulation of central tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002646 Any process that modulates the frequency, rate, or extent of central tolerance induction. CHEBI:145742 (Z)-3-amino-2-methylacrylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145742 GO:0002640 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0002640 GO:0002641 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0002641 GO:0002642 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0002642 GO:0061020 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0061020 GO:1905870 positive regulation of 3'-UTR-mediated mRNA stabilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905870 up regulation of 3'-UTR-mediated mRNA stabilization|activation of 3'-untranslated region-mediated mRNA stabilization|up-regulation of 3'-untranslated region-mediated mRNA stabilization|upregulation of 3'-UTR-mediated mRNA stabilization|positive regulation of 3'-untranslated region-mediated mRNA stabilization|up regulation of 3'-untranslated region-mediated mRNA stabilization|up-regulation of 3'-UTR-mediated mRNA stabilization|activation of 3'-UTR-mediated mRNA stabilization|upregulation of 3'-untranslated region-mediated mRNA stabilization Any process that activates or increases the frequency, rate or extent of 3'-UTR-mediated mRNA stabilization. GO:0061021 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0061021 GO:1905871 regulation of protein localization to cell leading edge biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905871 regulation of protein localisation in cell leading edge|regulation of protein localisation to cell leading edge|regulation of protein localization in cell leading edge Any process that modulates the frequency, rate or extent of protein localization to cell leading edge. GO:0061022 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0061022 GO:1905872 negative regulation of protein localization to cell leading edge biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905872 downregulation of protein localization in cell leading edge|inhibition of protein localisation to cell leading edge|down regulation of protein localisation in cell leading edge|down regulation of protein localization to cell leading edge|downregulation of protein localisation in cell leading edge|negative regulation of protein localization in cell leading edge|down-regulation of protein localization in cell leading edge|downregulation of protein localization to cell leading edge|down regulation of protein localisation to cell leading edge|inhibition of protein localization in cell leading edge|down-regulation of protein localisation in cell leading edge|negative regulation of protein localisation in cell leading edge|downregulation of protein localisation to cell leading edge|down-regulation of protein localization to cell leading edge|inhibition of protein localisation in cell leading edge|inhibition of protein localization to cell leading edge|negative regulation of protein localisation to cell leading edge|down-regulation of protein localisation to cell leading edge|down regulation of protein localization in cell leading edge Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell leading edge. GO:0061023 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0061023 GO:0061024 membrane organization biolink:BiologicalProcess go-plus goslim_pir|goslim_drosophila|goslim_generic|goslim_pombe|goslim_chembl http://purl.obolibrary.org/obo/GO_0061024 cellular membrane organisation|cellular membrane organization|membrane organisation|membrane organization and biogenesis|single-organism membrane organization A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. GO:1905862 ferroxidase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1905862 A protein complex which is capable of ferroxidase activity. GO:1905863 obsolete invadopodium organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905863 OBSOLETE. A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an invadopodium. GO:0061025 membrane fusion biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0061025 Wikipedia:Lipid_bilayer_fusion single-organism membrane fusion|cellular membrane fusion The membrane organization process that joins two lipid bilayers to form a single membrane. GO:1905864 regulation of Atg1/ULK1 kinase complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905864 regulation of ATG1 kinase complex assembly|regulation of ATG1/ULK1 signaling complex assembly|regulation of Atg1p signalling complex formation|regulation of ATG1-ATG13 complex assembly|regulation of ULK1-ATG13-FIP200 complex assembly|regulation of ATG1-ATG13 complex formation|regulation of ULK1-ATG13-FIP200 complex formation|regulation of Atg1p signalling complex assembly|regulation of ATG1/ULK1 signaling complex formation|regulation of ATG1 kinase complex formation|regulation of ULK1-ATG13-RB1CC1 complex assembly|regulation of ULK1 signaling complex assembly|regulation of ULK1 signaling complex formation|regulation of ATG1/ULK1 kinase complex formation|regulation of ULK1-ATG13-RB1CC1 complex formation Any process that modulates the frequency, rate or extent of Atg1/ULK1 kinase complex assembly. GO:0061026 cardiac muscle tissue regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061026 The regrowth of cardiac muscle tissue to repair injured or damaged muscle fibers in the postnatal stage. GO:1905865 negative regulation of Atg1/ULK1 kinase complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905865 downregulation of ULK1-ATG13-RB1CC1 complex formation|downregulation of ATG1/ULK1 signaling complex assembly|inhibition of ATG1 kinase complex formation|down regulation of ATG1 kinase complex assembly|down-regulation of ULK1 signaling complex assembly|downregulation of Atg1p signalling complex formation|negative regulation of ULK1 signaling complex assembly|inhibition of ATG1 kinase complex assembly|down regulation of ATG1-ATG13 complex assembly|downregulation of ULK1-ATG13-FIP200 complex assembly|down regulation of ATG1/ULK1 signaling complex assembly|down-regulation of ULK1-ATG13-RB1CC1 complex assembly|down regulation of Atg1p signalling complex formation|negative regulation of ULK1-ATG13-RB1CC1 complex assembly|inhibition of ATG1/ULK1 kinase complex assembly|down regulation of ULK1-ATG13-FIP200 complex formation|downregulation of ATG1-ATG13 complex formation|inhibition of ATG1/ULK1 signaling complex assembly|downregulation of ATG1-ATG13 complex assembly|down regulation of ULK1-ATG13-FIP200 complex assembly|inhibition of Atg1p signalling complex formation|down-regulation of ULK1-ATG13-RB1CC1 complex formation|inhibition of ULK1 signaling complex assembly|negative regulation of ULK1-ATG13-RB1CC1 complex formation|down regulation of Atg1p signalling complex assembly|down regulation of ATG1/ULK1 signaling complex formation|inhibition of ULK1-ATG13-FIP200 complex assembly|down regulation of ATG1-ATG13 complex formation|downregulation of ULK1-ATG13-FIP200 complex formation|down-regulation of ULK1 signaling complex formation|inhibition of ATG1-ATG13 complex formation|down regulation of ATG1 kinase complex formation|downregulation of Atg1p signalling complex assembly|negative regulation of ULK1 signaling complex formation|downregulation of ATG1/ULK1 signaling complex formation|downregulation of ULK1-ATG13-RB1CC1 complex assembly|down-regulation of ATG1/ULK1 kinase complex formation|inhibition of ULK1-ATG13-RB1CC1 complex formation|negative regulation of ATG1/ULK1 kinase complex formation|negative regulation of ATG1-ATG13 complex assembly|downregulation of ATG1 kinase complex formation|down-regulation of ATG1-ATG13 complex assembly|down regulation of ATG1/ULK1 kinase complex assembly|down regulation of ULK1-ATG13-RB1CC1 complex assembly|down-regulation of ULK1-ATG13-FIP200 complex formation|negative regulation of ULK1-ATG13-FIP200 complex formation|down regulation of ULK1 signaling complex assembly|inhibition of ULK1-ATG13-RB1CC1 complex assembly|down-regulation of ATG1 kinase complex assembly|negative regulation of ATG1 kinase complex assembly|negative regulation of Atg1p signalling complex assembly|downregulation of ULK1 signaling complex formation|downregulation of ATG1/ULK1 kinase complex assembly|down-regulation of Atg1p signalling complex assembly|negative regulation of ATG1/ULK1 signaling complex formation|down-regulation of ATG1/ULK1 signaling complex formation|negative regulation of ATG1/ULK1 signaling complex assembly|down-regulation of ATG1/ULK1 signaling complex assembly|inhibition of ATG1-ATG13 complex assembly|down-regulation of Atg1p signalling complex formation|downregulation of ULK1 signaling complex assembly|negative regulation of Atg1p signalling complex formation|downregulation of ATG1/ULK1 kinase complex formation|down regulation of ULK1 signaling complex formation|down-regulation of ATG1 kinase complex formation|negative regulation of ATG1 kinase complex formation|down-regulation of ULK1-ATG13-FIP200 complex assembly|negative regulation of ULK1-ATG13-FIP200 complex assembly|inhibition of ULK1-ATG13-FIP200 complex formation|inhibition of ULK1 signaling complex formation|down regulation of ULK1-ATG13-RB1CC1 complex formation|down regulation of ATG1/ULK1 kinase complex formation|inhibition of Atg1p signalling complex assembly|downregulation of ATG1 kinase complex assembly|down-regulation of ATG1-ATG13 complex formation|negative regulation of ATG1-ATG13 complex formation|inhibition of ATG1/ULK1 signaling complex formation|inhibition of ATG1/ULK1 kinase complex formation|down-regulation of ATG1/ULK1 kinase complex assembly Any process that stops, prevents or reduces the frequency, rate or extent of Atg1/ULK1 kinase complex assembly. GO:0061027 umbilical cord development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061027 The process whose specific outcome is the development of the umbilical cord, from its formation to the mature structure. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta. GO:1905866 positive regulation of Atg1/ULK1 kinase complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905866 upregulation of ATG1/ULK1 kinase complex formation|activation of ULK1-ATG13-RB1CC1 complex assembly|upregulation of ATG1-ATG13 complex assembly|up regulation of ULK1-ATG13-FIP200 complex assembly|up-regulation of ATG1 kinase complex formation|positive regulation of ATG1-ATG13 complex formation|up regulation of ULK1-ATG13-RB1CC1 complex formation|upregulation of ULK1-ATG13-FIP200 complex formation|up regulation of ATG1-ATG13 complex formation|positive regulation of ULK1-ATG13-RB1CC1 complex formation|activation of ULK1-ATG13-RB1CC1 complex formation|upregulation of ATG1 kinase complex assembly|up-regulation of ATG1/ULK1 kinase complex assembly|upregulation of Atg1p signalling complex assembly|up-regulation of ULK1 signaling complex formation|upregulation of ATG1/ULK1 signaling complex formation|activation of ULK1 signaling complex formation|upregulation of ATG1/ULK1 signaling complex assembly|up-regulation of ATG1/ULK1 kinase complex formation|up-regulation of ULK1 signaling complex assembly|upregulation of Atg1p signalling complex formation|activation of ATG1/ULK1 kinase complex formation|positive regulation of ULK1-ATG13-RB1CC1 complex assembly|upregulation of ATG1 kinase complex formation|upregulation of ULK1-ATG13-FIP200 complex assembly|up regulation of ATG1-ATG13 complex assembly|up regulation of ULK1-ATG13-RB1CC1 complex assembly|activation of ATG1-ATG13 complex assembly|positive regulation of ATG1-ATG13 complex assembly|up regulation of ULK1-ATG13-FIP200 complex formation|up-regulation of ATG1 kinase complex assembly|upregulation of ATG1-ATG13 complex formation|upregulation of ATG1/ULK1 kinase complex assembly|activation of ATG1 kinase complex assembly|up regulation of Atg1p signalling complex assembly|activation of ULK1-ATG13-FIP200 complex formation|positive regulation of ULK1-ATG13-FIP200 complex formation|up-regulation of ULK1-ATG13-RB1CC1 complex formation|up-regulation of ATG1/ULK1 signaling complex assembly|up regulation of ATG1/ULK1 signaling complex formation|positive regulation of ULK1 signaling complex formation|up-regulation of Atg1p signalling complex formation|activation of ATG1/ULK1 signaling complex assembly|positive regulation of Atg1p signalling complex assembly|upregulation of ULK1 signaling complex assembly|activation of Atg1p signalling complex assembly|up regulation of ULK1 signaling complex formation|activation of Atg1p signalling complex formation|positive regulation of ATG1/ULK1 signaling complex formation|activation of ATG1/ULK1 signaling complex formation|up regulation of ATG1 kinase complex formation|positive regulation of ATG1/ULK1 kinase complex formation|up-regulation of ULK1-ATG13-FIP200 complex assembly|activation of ULK1-ATG13-FIP200 complex assembly|positive regulation of ATG1 kinase complex formation|activation of ATG1 kinase complex formation|up regulation of ATG1/ULK1 kinase complex formation|upregulation of ULK1-ATG13-RB1CC1 complex assembly|up-regulation of ATG1-ATG13 complex formation|up-regulation of ATG1-ATG13 complex assembly|activation of ATG1-ATG13 complex formation|up regulation of ATG1/ULK1 kinase complex assembly|upregulation of ULK1-ATG13-RB1CC1 complex formation|positive regulation of ATG1 kinase complex assembly|activation of ATG1/ULK1 kinase complex assembly|up-regulation of ULK1-ATG13-FIP200 complex formation|up regulation of ATG1 kinase complex assembly|up regulation of ULK1 signaling complex assembly|positive regulation of ATG1/ULK1 signaling complex assembly|up-regulation of Atg1p signalling complex assembly|upregulation of ULK1 signaling complex formation|positive regulation of Atg1p signalling complex formation|up-regulation of ATG1/ULK1 signaling complex formation|activation of ULK1 signaling complex assembly|positive regulation of ULK1 signaling complex assembly|up regulation of ATG1/ULK1 signaling complex assembly|up regulation of Atg1p signalling complex formation|up-regulation of ULK1-ATG13-RB1CC1 complex assembly|positive regulation of ULK1-ATG13-FIP200 complex assembly Any process that activates or increases the frequency, rate or extent of Atg1/ULK1 kinase complex assembly. GO:0061028 establishment of endothelial barrier biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061028 The establishment of a barrier between endothelial cell layers, such as those in the brain, lung or intestine, to exert specific and selective control over the passage of water and solutes, thus allowing formation and maintenance of compartments that differ in fluid and solute composition. GO:1905867 epididymis development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905867 epididymus development The process whose specific outcome is the progression of an epididymis over time, from its formation to the mature structure. GO:0061029 eyelid development in camera-type eye biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061029 The progression of the eyelid in a camera-type eye from its formation to the mature state. The eyelid is a membranous cover that helps protect and lubricate the eye. GO:1905868 regulation of 3'-UTR-mediated mRNA stabilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905868 regulation of 3'-untranslated region-mediated mRNA stabilization Any process that modulates the frequency, rate or extent of 3'-UTR-mediated mRNA stabilization. GO:1905869 negative regulation of 3'-UTR-mediated mRNA stabilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905869 inhibition of 3'-UTR-mediated mRNA stabilization|negative regulation of 3'-untranslated region-mediated mRNA stabilization|down-regulation of 3'-untranslated region-mediated mRNA stabilization|downregulation of 3'-untranslated region-mediated mRNA stabilization|down regulation of 3'-untranslated region-mediated mRNA stabilization|inhibition of 3'-untranslated region-mediated mRNA stabilization|down-regulation of 3'-UTR-mediated mRNA stabilization|downregulation of 3'-UTR-mediated mRNA stabilization|down regulation of 3'-UTR-mediated mRNA stabilization Any process that stops, prevents or reduces the frequency, rate or extent of 3'-UTR-mediated mRNA stabilization. GO:0051690 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051690 CHEBI:145747 phosphatidylethanolamine 42:5 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145747 GO:0051691 cellular oligosaccharide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051691 cellular oligosaccharide metabolism The chemical reactions and pathways involving oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages, as carried out by individual cells. CHEBI:145748 PE(18:4_24:1) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145748 CHEBI:145749 PE(24:1/18:4) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145749 GO:0051694 pointed-end actin filament capping biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051694 minus-end actin filament capping activity|pointed-end F-actin capping activity|minus-end F-actin capping activity|pointed-end actin capping activity The binding of a protein or protein complex to the pointed (or minus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits. GO:0002647 negative regulation of central tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002647 down-regulation of central tolerance induction|inhibition of central tolerance induction|down regulation of central tolerance induction|downregulation of central tolerance induction Any process that stops, prevents, or reduces the frequency, rate, or extent of central tolerance induction. GO:0002648 positive regulation of central tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002648 up regulation of central tolerance induction|activation of central tolerance induction|stimulation of central tolerance induction|up-regulation of central tolerance induction|upregulation of central tolerance induction Any process that activates or increases the frequency, rate, or extent of central tolerance induction. GO:0051695 actin filament uncapping biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051695 F-actin uncapping The removal of capping protein from the end of actin filaments to free the ends for addition, exchange or removal of further actin subunits. GO:0051692 cellular oligosaccharide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051692 cellular oligosaccharide degradation|cellular oligosaccharide breakdown|cellular oligosaccharide catabolism The chemical reactions and pathways resulting in the breakdown of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages, as carried out by individual cells. GO:0002649 regulation of tolerance induction to self antigen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002649 Any process that modulates the frequency, rate, or extent of tolerance induction to self antigen. GO:0051693 actin filament capping biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051693 actin capping activity|F-actin capping activity The binding of a protein or protein complex to the end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits. GO:0002654 positive regulation of tolerance induction dependent upon immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002654 stimulation of tolerance induction dependent upon immune response|activation of tolerance induction dependent upon immune response|up-regulation of tolerance induction dependent upon immune response|positive regulation of immune response-dependent tolerance induction|up regulation of tolerance induction dependent upon immune response|upregulation of tolerance induction dependent upon immune response Any process that activates or increases the frequency, rate, or extent of tolerance induction dependent upon immune response. GO:0099600 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0099600 GO:0002655 regulation of tolerance induction to nonself antigen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002655 Any process that modulates the frequency, rate, or extent of tolerance induction to nonself antigen. GO:0002656 negative regulation of tolerance induction to nonself antigen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002656 down-regulation of tolerance induction to nonself antigen|downregulation of tolerance induction to nonself antigen|down regulation of tolerance induction to nonself antigen|inhibition of tolerance induction to nonself antigen Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to nonself antigen. GO:0002657 positive regulation of tolerance induction to nonself antigen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002657 up-regulation of tolerance induction to nonself antigen|activation of tolerance induction to nonself antigen|up regulation of tolerance induction to nonself antigen|upregulation of tolerance induction to nonself antigen|stimulation of tolerance induction to nonself antigen Any process that activates or increases the frequency, rate, or extent of tolerance induction to nonself antigen. GO:0002650 negative regulation of tolerance induction to self antigen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002650 down-regulation of tolerance induction to self antigen|inhibition of tolerance induction to self antigen|down regulation of tolerance induction to self antigen|downregulation of tolerance induction to self antigen Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to self antigen. CHEBI:51356 penicillinate anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_51356 GO:0002651 positive regulation of tolerance induction to self antigen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002651 up regulation of tolerance induction to self antigen|activation of tolerance induction to self antigen|stimulation of tolerance induction to self antigen|up-regulation of tolerance induction to self antigen|upregulation of tolerance induction to self antigen Any process that activates or increases the frequency, rate, or extent of tolerance induction to self antigen. GO:0002652 regulation of tolerance induction dependent upon immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002652 regulation of immune response-dependent tolerance induction Any process that modulates the frequency, rate, or extent of tolerance induction dependent upon immune response. GO:0002653 negative regulation of tolerance induction dependent upon immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002653 down-regulation of tolerance induction dependent upon immune response|downregulation of tolerance induction dependent upon immune response|negative regulation of immune response-dependent tolerance induction|down regulation of tolerance induction dependent upon immune response|inhibition of tolerance induction dependent upon immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction dependent upon immune response. CHEBI:145735 (Z)-3-amino-2-methylacrylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_145735 GO:1905880 negative regulation of oogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905880 down-regulation of ovum development|negative regulation of ovum development|down regulation of oogenesis|downregulation of oogenesis|downregulation of ovum development|down regulation of ovum development|down-regulation of oogenesis|inhibition of ovum development|inhibition of oogenesis Any process that stops, prevents or reduces the frequency, rate or extent of oogenesis. GO:1905881 positive regulation of oogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905881 upregulation of oogenesis|positive regulation of ovum development|up regulation of ovum development|up regulation of oogenesis|activation of oogenesis|upregulation of ovum development|up-regulation of oogenesis|up-regulation of ovum development|activation of ovum development Any process that activates or increases the frequency, rate or extent of oogenesis. GO:0061010 gall bladder development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061010 The progression of the gall bladder over time, from its initial formation to the mature structure. The gall bladder is a cavitated organ that stores bile. GO:1905882 obsolete other organism cell wall biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1905882 OBSOLETE. Any cell wall that is part of a other organism. GO:0061011 hepatic duct development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061011 The progression of the hepatic duct over time, from its formation to the mature structure. The hepatic duct is the duct that leads from the liver to the common bile duct. GO:0061012 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0061012 GO:1905883 regulation of triglyceride transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905883 regulation of triacylglycerol transport Any process that modulates the frequency, rate or extent of triglyceride transport. GO:1905873 positive regulation of protein localization to cell leading edge biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905873 upregulation of protein localisation in cell leading edge|up-regulation of protein localisation to cell leading edge|up regulation of protein localization in cell leading edge|upregulation of protein localization to cell leading edge|positive regulation of protein localization in cell leading edge|activation of protein localization in cell leading edge|up regulation of protein localisation in cell leading edge|upregulation of protein localisation to cell leading edge|positive regulation of protein localisation in cell leading edge|activation of protein localisation in cell leading edge|up regulation of protein localization to cell leading edge|activation of protein localization to cell leading edge|up-regulation of protein localization in cell leading edge|up regulation of protein localisation to cell leading edge|positive regulation of protein localisation to cell leading edge|activation of protein localisation to cell leading edge|up-regulation of protein localisation in cell leading edge|upregulation of protein localization in cell leading edge|up-regulation of protein localization to cell leading edge Any process that activates or increases the frequency, rate or extent of protein localization to cell leading edge. GO:0061013 regulation of mRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061013 regulation of mRNA decay Any process that modulates the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. GO:1905874 regulation of postsynaptic density organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905874 regulation of postsynaptic density organisation|regulation of post synaptic density organization|regulation of PSD organization|regulation of post-synaptic density organization Any process that modulates the frequency, rate or extent of postsynaptic density organization. GO:0061014 positive regulation of mRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061014 positive regulation of mRNA decay Any process that increases the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. GO:1905875 negative regulation of postsynaptic density organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905875 negative regulation of PSD organization|down-regulation of PSD organization|inhibition of postsynaptic density organization|down regulation of postsynaptic density organisation|downregulation of post synaptic density organization|downregulation of PSD organization|downregulation of postsynaptic density organisation|negative regulation of post-synaptic density organization|down-regulation of post-synaptic density organization|down regulation of post synaptic density organization|down regulation of PSD organization|inhibition of post synaptic density organization|down regulation of postsynaptic density organization|inhibition of PSD organization|downregulation of postsynaptic density organization|down-regulation of postsynaptic density organisation|negative regulation of postsynaptic density organisation|downregulation of post-synaptic density organization|down regulation of post-synaptic density organization|inhibition of post-synaptic density organization|inhibition of postsynaptic density organisation|down-regulation of postsynaptic density organization|down-regulation of post synaptic density organization|negative regulation of post synaptic density organization Any process that stops, prevents or reduces the frequency, rate or extent of postsynaptic density organization. GO:0061015 snRNA import into nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061015 The directed movement of snRNA, small nuclear ribonucleic acid into the nucleus. GO:1905876 positive regulation of postsynaptic density organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905876 up-regulation of postsynaptic density organization|positive regulation of post synaptic density organization|upregulation of postsynaptic density organisation|positive regulation of PSD organization|up-regulation of post-synaptic density organization|activation of post-synaptic density organization|up regulation of post synaptic density organization|up regulation of PSD organization|upregulation of postsynaptic density organization|up regulation of postsynaptic density organisation|activation of postsynaptic density organisation|upregulation of post synaptic density organization|positive regulation of postsynaptic density organisation|positive regulation of post-synaptic density organization|upregulation of PSD organization|up regulation of post-synaptic density organization|up regulation of postsynaptic density organization|activation of postsynaptic density organization|up-regulation of post synaptic density organization|activation of post synaptic density organization|activation of PSD organization|up-regulation of PSD organization|up-regulation of postsynaptic density organisation|upregulation of post-synaptic density organization Any process that activates or increases the frequency, rate or extent of postsynaptic density organization. GO:0061016 snRNA localization to Cajal body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061016 The directed movement of snRNA, small nuclear ribonucleic acid, to a Cajal body. GO:0061017 hepatoblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061017 The process in which a relatively unspecialized cell acquires specialized features of a hepatoblast. A hepatoblast is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into hepatocytes and cholangiocytes. GO:1905877 obsolete invadopodium assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905877 invadopodium formation OBSOLETE. The aggregation, arrangement and bonding together of a set of components to form an invadopodium. GO:0061018 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0061018 GO:1905878 obsolete invadopodium disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905878 OBSOLETE. The disaggregation of an invadopodium into its constituent components. OBO:go/extensions/ro_pending#results_in_connection_of obsolete results_in_connection_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/go/extensions/ro_pending#results_in_connection_of GO:0061019 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0061019 GO:0099609 microtubule lateral binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0099609 Interacting selectively and non-covalently with the side of a microtubule. GO:1905879 regulation of oogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905879 regulation of ovum development Any process that modulates the frequency, rate or extent of oogenesis. GO:0099607 lateral attachment of mitotic spindle microtubules to kinetochore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099607 The cell cycle process in which sister chromatids become laterally attached to spindle microtubules as part of mitotic metaphase plate congression. Attachment precedes migration along microtubules towards the spindle equator (metaphase plate). GO:0099608 regulation of action potential firing pattern biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099608 spike train sculpting Any process that regulates the temporal pattern of a sequence of action potentials in a neuron. CHEBI:51353 N-carbamoyl-L-alpha-amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51353 GO:0099605 regulation of action potential firing rate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099605 Any process that regulates the frequency of action potentials in a spike train. CHEBI:51354 benzylpenicillin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_51354 GO:0099606 microtubule plus-end directed mitotic chromosome migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099606 plus-end directed chromosome gliding The cell cycle process in which chromosomes that are laterally attached to one or more mitotic spindle microtubules migrate towards the spindle equator via plus-end-directed movement along the microtubules. This process is part of mitotic metaphase plate congression. GO:0099603 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0099603 GO:0002658 regulation of peripheral tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002658 Any process that modulates the frequency, rate, or extent of peripheral tolerance induction. GO:0002659 negative regulation of peripheral tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002659 inhibition of peripheral tolerance induction|down-regulation of peripheral tolerance induction|downregulation of peripheral tolerance induction|down regulation of peripheral tolerance induction Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral tolerance induction. GO:0099604 ligand-gated calcium channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0099604 Enables the transmembrane transfer of a calcium ions by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts. GO:0099601 regulation of neurotransmitter receptor activity biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099601 Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity. Modulation may be via an effect on ligand affinity, or effector funtion such as ion selectivity or pore opening/closing in ionotropic receptors. GO:0099602 neurotransmitter receptor regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0099602 A molecular function that directly (via physical interaction or direct modification) activates, inhibits or otherwise modulates the activity of a neurotransmitter receptor. Modulation of activity includes changes in desensitization rate, ligand affinity, ion selectivity and pore-opening/closing. GO:0036080 purine nucleotide-sugar transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036080 Enables the transfer of a purine nucleotide-sugar from one side of a membrane to the other. Purine nucleotide-sugars are purine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative. GO:0036081 extracellular ammonia-gated ion channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036081 ionotropic ammonia receptor activity Enables the transmembrane transfer of an ion by a channel that opens when extracellular ammonia (NH3) has been bound by the channel complex or one of its constituent parts. GO:0036079 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0036079 CHEBI:90955 bacteriochlorophyllide d(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90955 CHEBI:90956 2-exo-hydroxy-1,4-cineole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90956 GO:0036071 N-glycan fucosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036071 glycoprotein fucosylation The process of transferring a fucosyl group to an N-glycan. An N-glycan is the carbohydrate portion of an N-glycoprotein when attached to a nitrogen from asparagine or arginine side-chains. GO:0036072 direct ossification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036072 The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance, that does not require the replacement of preexisting tissues. GO:0036073 perichondral ossification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036073 Intramembranous ossification from the surface of a cartilage element as the perichondrium becomes a periosteum, without replacement of cartilage. GO:0036074 metaplastic ossification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036074 metaplasia Direct ossification in which bone formation occurs as result of the direct transformation of non-bone cells into bone cells without cell division. GO:0036075 replacement ossification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036075 indirect ossification Ossification that requires the replacement of a preexisting tissue prior to bone tissue formation. GO:0036076 ligamentous ossification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036076 Ossification wherein bone tissue forms within ligamentous tissue. GO:0036077 intratendonous ossification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036077 Ossification wherein bone tissue forms within tendonous tissue. GO:0036078 minus-end specific microtubule depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036078 The removal of tubulin heterodimers from the minus end of a microtubule. CHEBI:75311 methyl aklanonate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75311 CHEBI:75327 (8S,9S)-epoxy-(10R)-hydroxyicosa-(5Z,11Z,14Z)-trienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75327 CHEBI:75325 cathartic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75325 CHEBI:75326 8-oxo-ETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75326 UBERON:4300173 pelvic fin bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_4300173 A paired fin bud that develops into a pelvic fin. GO:0036070 light-independent bacteriochlorophyll biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036070 light-independent bacteriochlorophyll anabolism|light-independent bacteriochlorophyll biosynthesis|light-independent bacteriochlorophyll synthesis|light-independent bacteriochlorophyll formation|light independent bacteriochlorophyll biosynthetic process The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, which occur in the absence of light. Bacteriochlorophylls are any of the chlorophylls of photosynthetic bacteria; they differ structurally from the chlorophylls of higher plants. UBERON:4300172 pectoral fin bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_4300172 A paired fin bud that develops into a pectoral fin. GO:0036068 light-independent chlorophyll biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036068 light-independent chlorophyll anabolism|light-independent chlorophyll synthesis|light-independent chlorophyll formation|light-independent chlorophyll biosynthesis|light independent chlorophyll biosynthetic process The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors, which occur in the absence of light. CHEBI:90946 dTDP-4-(methylammonio)-2,3,4,6-tetradeoxy-alpha-D-glucose(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90946 CHEBI:90947 dTDP-alpha-D-forosamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90947 GO:0036069 light-dependent bacteriochlorophyll biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036069 light-dependent bacteriochlorophyll synthesis|light-dependent bacteriochlorophyll formation|light-dependent bacteriochlorophyll biosynthesis|light dependent bacteriochlorophyll biosynthetic process|light-dependent bacteriochlorophyll anabolism The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, which occur in the presence of light. Bacteriochlorophylls are any of the chlorophylls of photosynthetic bacteria; they differ structurally from the chlorophylls of higher plants. CHEBI:90944 dTDP-4-dehydro-2,3,6-trideoxy-alpha-D-glucose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90944 CHEBI:90945 dTDP-4-ammonio-2,3,4,6-tetradeoxy-alpha-D-glucose(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90945 GO:0036060 slit diaphragm assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036060 The aggregation, arrangement and bonding together of a set of components to form a slit diaphragm, specialized cell-cell junction found between the interdigitating foot processes of the glomerular epithelium (the podocytes) in the vertebrate kidney, which is adapted for facilitating glomerular filtration. GO:0036061 muscle cell chemotaxis toward tendon cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036061 muscle cell attraction|muscle cell chemotaxis towards tendon cell The directed movement of a muscle cell towards a tendon cell in response to an external stimulus. Tendon cells, for example, produce positive guidance cues that attract muscle cells. CHEBI:75320 2-amino-5-chloro-cis,cis-muconic 6-semialdehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75320 CHEBI:90940 N-acetyl-L-phosphinothricin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90940 GO:0036062 presynaptic periactive zone biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036062 pre-synaptic periactive zone|periactive zone A region that surrounds the active zone of the presynaptic plasma membrane, and is specialized for the control of synaptic development. GO:0036063 acroblast biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036063 spermatid acroblast A cone-shaped structure in the head of a spermatozoon, which is formed by the coalescence of Golgi fragments following the completion of meiosis. The acroblast is situated adjacent to the acrosomal vesicle. GO:0036064 ciliary basal body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036064 NIF_Subcellular:sao11978067 basal body|cilium basal body|cilial basal body|microtubule basal body|kinetosome A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport. GO:0036065 fucosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036065 The covalent attachment of a fucosyl group to an acceptor molecule. GO:0036066 protein O-linked fucosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036066 The process of transferring a fucosyl group to a serine or threonine residues in a protein acceptor molecule, to form an O-linked protein-sugar linkage. GO:0036067 light-dependent chlorophyll biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036067 light-dependent chlorophyll synthesis|light-dependent chlorophyll formation|light-dependent chlorophyll biosynthesis|light dependent chlorophyll biosynthetic process|light-dependent chlorophyll anabolism The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors, which occur in the presence of light. CHEBI:75322 8(S)-HPETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75322 GO:0036057 slit diaphragm biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036057 A specialized cell-cell junction found between the interdigitating foot processes of the glomerular epithelium (the podocytes) in the vertebrate kidney, which is adapted for facilitating glomerular filtration. CHEBI:90979 5,20-DiHETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90979 GO:0036058 filtration diaphragm assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036058 The aggregation, arrangement and bonding together of a set of components to form a filtration diaphragm, a specialized cell-cell junction found between the cells of the excretory system, which provides a barrier for filtration of blood or hemolymph. GO:0036059 nephrocyte diaphragm assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036059 The aggregation, arrangement and bonding together of a set of components to form a nephrocyte diaphragm, a specialized cell-cell junction found between nephrocytes of the insect kidney. CHEBI:90975 O(4)-(N-acetyl-alpha-D-galactosaminyl)-trans-4-hydroxy-L-proline residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90975 CHEBI:90976 20-hydroxylipoxin A4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90976 CHEBI:90978 20-hydroxylipoxin B4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90978 GO:0036050 peptidyl-lysine succinylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036050 RESID:AA0545 The modification of a peptidyl-lysine residue by the addition of a succinyl group (CO-CH2-CH2-CO) to form N6-succinyl-L-lysine. GO:0036051 protein localization to trailing edge biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036051 protein localisation to trailing edge A process in which a protein is transported to, or maintained at, the trailing edge. The trailing edge is the area of a motile cell opposite to the direction of movement. GO:0036052 protein localization to uropod biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036052 protein localisation to uropod A process in which a protein is transported to, or maintained in, a uropod. A uropod is a membrane projection with related cytoskeletal components at the trailing edge of a migrating cell. GO:0036053 glomerular endothelium fenestra biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036053 GEnC fenestration|glomerular endothelial cell fenestration A large plasma membrane-lined circular pore that perforates the flattened glomerular endothelium and, unlike those of other fenestrated capillaries, is not spanned by diaphragms; the density and size of glomerular fenestrae account, at least in part, for the high permeability of the glomerular capillary wall to water and small solutes. GO:0036054 protein-malonyllysine demalonylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036054 peptidyl-malonyllysine demalonylase activity|protein malonyl lysine demalonylation activity|protein lysine demalonylation activity Catalysis of the reaction: protein-malonyllysine + H2O => protein-lysine + malonate. This reaction is the removal of a malonyl group (CO-CH2-CO) from a malonylated lysine residue of a protein or peptide. GO:0036055 protein-succinyllysine desuccinylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036055 RHEA:47668 peptidyl-succinyllysine desuccinylase activity|succinyl lysine desuccinylase activity|succinyllysine desuccinylase activity Catalysis of the reaction: H2O + N(6)-succinyl-L-lysyl-[protein] + NAD(+) = 2''-O-succinyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide. CHEBI:75332 nonadecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75332 GO:0036056 filtration diaphragm biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036056 A specialized cell-cell junction found between the cells of the excretory system, which provides a barrier for filtration of blood or hemolymph. CHEBI:90970 1alpha,23(S),25-trihydroxyvitamin D3 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90970 CHEBI:75348 (8E,10S,12Z,15Z)-10-hydroperoxyoctadec-8,12,15-trienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75348 GO:0036046 protein demalonylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036046 The removal of a malonyl group (CO-CH2-CO), from an amino acid residue within a protein or peptide. CHEBI:90968 3-vinyl-bacteriochlorophyllide d(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90968 GO:0036047 peptidyl-lysine demalonylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036047 The process of removing a malonyl group (CO-CH2-CO) from an malonylated lysine residue in a peptide or protein. CHEBI:90969 7-hydroxybacteriochlorophyllide c(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90969 GO:0036048 protein desuccinylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036048 The removal of a succinyl group (CO-CH2-CH2-CO) from a residue in a peptide or protein. GO:0036049 peptidyl-lysine desuccinylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036049 The removal of a succinyl group (CO-CH2-CH2-CO) from a succinylated lysine residue in a peptide or protein. CHEBI:90964 8,12-diethyl-3-vinylbacteriochlorophyllide d(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90964 CHEBI:90965 bacteriochlorophyllide c(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90965 CHEBI:90966 12-ethyl-8-propyl-3-vinylbacteriochlorophyllide d(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90966 CHEBI:90967 12-ethyl-8-isobutyl-3-vinylbacteriochlorophyllide d(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90967 CHEBI:75341 (8E,10S)-10-hydroperoxy-8-octadecenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75341 CHEBI:75342 1-oleoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75342 GO:0036040 curcumin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036040 (1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione catabolism|curcumin breakdown|diferuloylmethane catabolism|turmeric yellow catabolism|turmeric yellow degradation|diferuloylmethane degradation|turmeric yellow breakdown|(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione degradation|diferuloylmethane breakdown|curcumin catabolism|turmeric yellow catabolic process|diferuloylmethane catabolic process|(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione breakdown|(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione catabolic process|curcumin degradation The chemical reactions and pathways resulting in the breakdown of the polyphenol, curcumin. GO:0036041 long-chain fatty acid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036041 long chain fatty acid binding Interacting selectively and non-covalently with a long-chain fatty acid. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22. CHEBI:90963 3-vinylbacteriochlorophyllide d(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90963 GO:0036042 long-chain fatty acyl-CoA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036042 long-chain fatty acyl-coenyme A binding Interacting selectively and non-covalently with a long-chain fatty acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more. CHEBI:75346 (8E,10S,12Z)-10-hydroperoxyoctadeca-8,12-dienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75346 GO:0036043 obsolete microspike biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036043 microspike OBSOLETE. A dynamic, actin-rich projection extending from the surface of a migrating animal cell. GO:0036044 obsolete protein malonylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036044 protein malonylation OBSOLETE. The modification of a protein amino acid by the addition of a malonyl (CO-CH2-CO) group. GO:0036045 obsolete peptidyl-lysine malonylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036045 lysine malonylation|peptidyl-lysine malonylation OBSOLETE. The addition of a malonyl group (CO-CH2-CO) to peptidyl-lysine to form N6-malonyl-L-lysine. GO:0036035 osteoclast development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036035 osteoclast cell development The process whose specific outcome is the progression of a osteoclast from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue. GO:0036036 cardiac neural crest cell delamination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036036 The negative regulation of cell adhesion process in which a cardiac neural crest cell physically separates from the rest of the neural tube. CHEBI:131198 (Z)-1,2-ethenediol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131198 GO:0036037 CD8-positive, alpha-beta T cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036037 The change in morphology and behavior of a CD8-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. GO:0036038 MKS complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036038 MKS module|tectonic complex|TCTN-B9D complex|B9 complex|tectonic-like complex A protein complex that is located at the ciliary transition zone and consists of several proteins some of which are membrane bound. Acts as an organiser of transition zone inner structure, specifically the Y-shaped links, in conjunction with the NPHP complex. The MKS complex also acts as part of the selective barrier that prevents diffusion of proteins between the ciliary cytoplasm and cellular cytoplasm as well as between the ciliary membrane and plasma membrane. GO:0036039 curcumin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036039 diferuloylmethane metabolism|turmeric yellow metabolism|turmeric yellow metabolic process|diferuloylmethane metabolic process|(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione metabolic process|curcumin metabolism|(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione metabolism The chemical reactions and pathways involving the polyphenol, curcumin. CHEBI:90996 12(S)-HpEPE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90996 GO:0036030 protein C inhibitor-plasma kallikrein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036030 SERPINA5-plasma kallikrein complex|protein C inhibitor-KLKB1 complex|plasma serine protease inhibitor-plasma kallikrein complex|serpin A5-plasma kallikrein complex|PCI-plasma kallikrein complex A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and plasma kallikrein (KLK1B); formation of the complex inhibits the serine protease activity of plasma kallikrein. GO:0036031 recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036031 recruitment of guanylyltransferase to RNA polymerase II holoenzyme complex|capping enzyme targeting to RNA polymerase II The process in which the guanylyltransferase enzyme responsible for adding a 7-methylguanosine cap on pre-mRNA becomes associated with the RNA polymerase II holoenzyme complex and the 5' end of a transcript. CHEBI:75357 1-oleoyl-2-(11Z)-octadecenoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75357 GO:0036032 neural crest cell delamination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036032 neural crest cell emigration|neural crest cell segregation|neural crest cell individualization The negative regulation of cell adhesion process in which a neural crest cell physically separates from the rest of the neural tube. CHEBI:90990 12,20-DiHETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90990 GO:0036033 mediator complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036033 Interacting selectively and non-covalently with a mediator complex. The mediator complex is a protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins. CHEBI:75354 (11Z)-octadecenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75354 GO:0036034 mediator complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036034 The aggregation, arrangement and bonding together of a set of components to form a mediator complex. The mediator complex is a protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins. CHEBI:90992 20-hydroxy-6-trans-leukotriene B4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90992 GO:0051600 regulation of endocytosis by exocyst localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051600 regulation of site selection of endocytosis|spatial regulation of endocytosis|relocation of endocytosis|regulation of endocytosis by exocyst localisation Any process in which an exocyst is transported to, or maintained in, a specific location that results in the modulation of endocytosis. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse. GO:0051603 proteolysis involved in cellular protein catabolic process biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0051603 peptidolysis during cellular protein catabolism|proteolysis during cellular protein catabolic process|proteolysis during cellular protein catabolism|peptidolysis during cellular protein catabolic process|peptidolysis involved in cellular protein catabolic process|peptidolysis involved in cellular protein catabolism The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells. GO:0051604 protein maturation biolink:BiologicalProcess go-plus goslim_yeast|goslim_pir|goslim_drosophila|goslim_generic|goslim_pombe|goslim_chembl http://purl.obolibrary.org/obo/GO_0051604 Any process leading to the attainment of the full functional capacity of a protein. GO:0051601 exocyst localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051601 exocyst localisation|establishment and maintenance of exocyst localization Any process in which an exocyst is transported to, or maintained in, a specific location. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse. GO:0051602 response to electrical stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051602 response to electricity Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. GO:0051607 defense response to virus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051607 defence response to virus|defense response to viruses|antiviral response Reactions triggered in response to the presence of a virus that act to protect the cell or organism. GO:0051608 histamine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051608 The directed movement of histamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. GO:0051605 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051605 GO:0051606 detection of stimulus biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0051606 perception of stimulus|stimulus sensing|stimulus detection The series of events in which a stimulus is received by a cell or organism and converted into a molecular signal. GO:0051609 inhibition of neurotransmitter uptake biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051609 inhibition of neurotransmitter import Any process that prevents the activation of the directed movement of a neurotransmitter into a cell. GO:0036024 protein C inhibitor-TMPRSS7 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036024 SERPINA5-TMPRSS7 complex|plasma serine protease inhibitor-TMPRSS7 complex|protein C inhibitor-matriptase-3 complex|serpin A5-TMPRSS7 complex|protein C inhibitor-transmembrane protease serine 7 complex|PCI-TMPRSS7 complex A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and transmembrane protease serine 7 (TMPRSS7); formation of the complex inhibits the serine protease activity of transmembrane protease serine 7. GO:0036025 protein C inhibitor-TMPRSS11E complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036025 plasma serine protease inhibitor-TMPRSS11E complex|serpin A5-TMPRSS11E complex|protein C inhibitor-transmembrane protease serine 11E complex|PCI-TMPRSS11E complex|SERPINA5-TMPRSS11E complex A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and transmembrane protease serine 11E (TMPRSS11E); formation of the complex inhibits the serine protease activity of transmembrane protease serine 11E. GO:0036026 protein C inhibitor-PLAT complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036026 serpin A5-PLAT complex|plasma serine protease inhibitor-PLAT complex|SERPINA5-PLAT complex|protein C inhibitor-tPA complex|protein C inhibitor-tissue-type plasminogen activator complex|PCI-PLAT complex A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and tissue-type plasminogen activator (PLAT); formation of the complex inhibits the serine protease activity of tissue-type plasminogen activator. GO:0036027 protein C inhibitor-PLAU complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036027 serpin A5-PLAU complex|protein C inhibitor-uPA complex|protein C inhibitor-urokinase-type plasminogen activator complex|plasma serine protease inhibitor-PLAU complex|protein C inhibitor-U-plasminogen activator complex|SERPINA5-PLAU complex|PCI-PLAU complex A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and urokinase-type plasminogen activator (PLAU); formation of the complex inhibits the serine protease activity of urokinase-type plasminogen activator. GO:0036028 protein C inhibitor-thrombin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036028 protein C inhibitor-coagulation factor II complex|PCI-thrombin complex|serpin A5-thrombin complex|plasma serine protease inhibitor-thrombin complex|SERPINA5-thrombin complex|protein C inhibitor-F2 complex A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and thrombin (F2); formation of the complex inhibits the serine protease activity of thrombin. CHEBI:90986 (20S,24S)-dihydroxyvitamin D3 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90986 GO:0036029 protein C inhibitor-KLK3 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036029 PCI-KLK3 complex|serpin A5-KLK3 complex|plasma serine protease inhibitor-KLK3 complex|protein C inhibitor-kallikrein-3 complex|SERPINA5-KLK3 complex|protein C inhibitor-prostate-specific antigen complex A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and prostate-specific antigen (KLK3); formation of the complex inhibits the serine protease activity of prostate-specific antigen. CHEBI:75360 (6Z)-octadecenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75360 CHEBI:90987 3-deoxy-D-glycero-beta-D-galacto-nonulosonate 9-phosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90987 CHEBI:90988 3-deoxy-D-glycero-beta-D-galacto-nonulosonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90988 CHEBI:90989 CMP-3-deoxy-D-glycero-beta-D-galacto-nonulosonate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90989 CHEBI:90982 8,20-DiHETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90982 CHEBI:75363 1-oleoyl-2-(6Z)-octadecenoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75363 CHEBI:90983 (20S)-hydroxyvitamin D3 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90983 CHEBI:90984 20(S),25-dihydroxyvitamin D3 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90984 CHEBI:90985 (20S,24R)-dihydroxyvitamin D3 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90985 GO:0036020 endolysosome membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036020 endolysosomal membrane The lipid bilayer surrounding an endolysosome. An endolysosome is a transient hybrid organelle formed by fusion of a late endosome with a lysosome. GO:0036021 endolysosome lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036021 endolysosomal lumen The volume enclosed by the membrane of an endolysosome. An endolysosome is a transient hybrid organelle formed by fusion of a late endosome with a lysosome. GO:0036022 limb joint morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036022 knee morphogenesis|leg joint morphogenesis The process in which the anatomical structures of a limb joint are generated and organized. A limb joint is a flexible region that separates the rigid sections of a limb to allow movement in a controlled manner. CHEBI:90980 23(S),25-dihydroxy-24-oxovitamin D3 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90980 GO:0036023 embryonic skeletal limb joint morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036023 The process, occurring in the embryo, in which the anatomical structures of a skeletal limb joint are generated and organized. A skeletal limb joint is the connecting structure between the bones of a limb. GO:0051610 serotonin uptake biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051610 5-hydroxytryptamine uptake|serotonin import|5HT uptake|5-HT uptake The directed movement of serotonin into a cell, typically presynaptic neurons or glial cells. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems. GO:0051611 regulation of serotonin uptake biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051611 regulation of serotonin import|regulation of 5HT uptake|regulation of 5-HT uptake|regulation of 5-hydroxytryptamine uptake Any process that modulates the frequency, rate or extent of the directed movement of the monoamine neurotransmitter serotonin into a cell. GO:0051614 inhibition of serotonin uptake biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051614 inhibition of 5-hydroxytryptamine uptake|inhibition of 5-HT uptake|inhibition of serotonin import|inhibition of 5HT uptake Any process that prevents the activation of the directed movement of serotonin into a cell. GO:0051615 histamine uptake biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051615 histamine import The directed movement of histamine into a cell, typically presynaptic neurons or glial cells. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. UBERON:5001466 pedal digit plus metapodial segment biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_5001466 pedal digit|pedal digit digitopodial subdivision|pedal digit ray|pedal digit ( phalanges plus metapodial) plus soft tissue A subdivision of the autopod consisting of pedal digit plus the region incorporating a single metapodial element. These segments are typically repeated along the pre-axiom to post-axial axis. GO:0051612 negative regulation of serotonin uptake biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051612 down-regulation of serotonin uptake|negative regulation of 5-hydroxytryptamine uptake|downregulation of serotonin uptake|down regulation of serotonin uptake|negative regulation of serotonin import|negative regulation of 5-HT uptake|negative regulation of 5HT uptake Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of serotonin into a cell. GO:0051613 positive regulation of serotonin uptake biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051613 up-regulation of serotonin uptake|activation of serotonin uptake|positive regulation of 5HT uptake|up regulation of serotonin uptake|positive regulation of 5-hydroxytryptamine uptake|upregulation of serotonin uptake|positive regulation of 5-HT uptake|positive regulation of serotonin import|stimulation of serotonin uptake Any process that activates or increases the frequency, rate or extent of the directed movement of serotonin into a cell. GO:0051618 positive regulation of histamine uptake biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051618 upregulation of histamine uptake|positive regulation of histamine import|stimulation of histamine uptake|activation of histamine uptake|up-regulation of histamine uptake|up regulation of histamine uptake Any process that activates or increases the frequency, rate or extent of the directed movement of histamine into a cell. GO:0051619 inhibition of histamine uptake biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051619 inhibition of histamine import Any process that prevents the activation of the directed movement of histamine into a cell. GO:0051616 regulation of histamine uptake biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051616 regulation of histamine import Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter histamine into a cell. GO:0051617 negative regulation of histamine uptake biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051617 negative regulation of histamine import|down-regulation of histamine uptake|downregulation of histamine uptake|down regulation of histamine uptake Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of histamine into a cell. GO:0036013 cyanelle outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036013 The outer, i.e. cytoplasm-facing, lipid bilayer of the cyanelle envelope. GO:0036014 cyanelle intermembrane space biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036014 cyanelle periplasm|cyanelle envelope lumen The region between the inner and outer lipid bilayers of the cyanelle envelope; includes the peptidoglycan layer. GO:0036015 response to interleukin-3 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036015 response to IL-3 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-3 stimulus. GO:0036016 cellular response to interleukin-3 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036016 cellular response to IL-3 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-3 stimulus. GO:0036017 response to erythropoietin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036017 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythropoietin stimulus. Erythropoietin is a glycoprotein hormone that controls erythropoiesis. CHEBI:75370 2-(2,4-dichlorophenoxy)propanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75370 GO:0036018 cellular response to erythropoietin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036018 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythropoietin stimulus. GO:0036019 endolysosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036019 An transient hybrid organelle formed by fusion of a late endosome with a lysosome, and in which active degradation takes place. CHEBI:75374 (S)-dichlorprop biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75374 CHEBI:131170 (3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[(2S)-2-[[[(1S)-1-carboxy-2-phenylethyl]amino]-oxomethyl]-1-pyrrolidinyl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-oxobutanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131170 CHEBI:75373 (R)-dichlorprop biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75373 CHEBI:75378 1-palmitoyl-2-lauroyl-sn-glycero-3-phospho-1D-myo-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75378 GO:0036010 protein localization to endosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036010 protein localization in endosome|protein localisation in endosome A process in which a protein is transported to, or maintained in, a location within an endosome. GO:0036011 imaginal disc-derived leg segmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036011 Division of an imaginal disc-derived leg into a series of semi-repetitive parts or segments. The Drosophila leg, for example, has nine segments, each separated from the next by a flexible joint. CHEBI:75376 1-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75376 GO:0036012 cyanelle inner membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036012 cyanelle inner envelope membrane The inner, i.e. lumen-facing, lipid bilayer of the cyanelle envelope; also faces the cyanelle stroma. GO:0051621 regulation of norepinephrine uptake biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051621 regulation of noradrenaline uptake|regulation of levarterenol uptake|regulation of norepinephrine import Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter norepinephrine into a cell. GO:0051622 negative regulation of norepinephrine uptake biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051622 negative regulation of levarterenol uptake|negative regulation of norepinephrine import|down regulation of norepinephrine uptake|downregulation of norepinephrine uptake|down-regulation of norepinephrine uptake|negative regulation of noradrenaline uptake Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of norepinephrine into a cell. GO:0051620 norepinephrine uptake biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051620 norepinephrine reuptake|levarterenol uptake|noradrenaline reuptake|norepinephrine import|levarterenol reuptake|noradrenaline uptake The directed movement of norepinephrine into a cell, typically presynaptic neurons or glial cells. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine. GO:0051625 epinephrine uptake biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051625 adrenaline uptake|epinephrine reuptake|adrenaline reuptake|epinephrine import The directed movement of epinephrine into a cell, typically presynaptic neurons or glial cells. Epinephrine is a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine. GO:0051626 regulation of epinephrine uptake biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051626 regulation of epinephrine import|regulation of adrenaline uptake Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter epinephrine into a cell. GO:0051623 positive regulation of norepinephrine uptake biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051623 positive regulation of norepinephrine import|upregulation of norepinephrine uptake|up regulation of norepinephrine uptake|activation of norepinephrine uptake|stimulation of norepinephrine uptake|up-regulation of norepinephrine uptake|positive regulation of levarterenol uptake|positive regulation of noradrenaline uptake Any process that activates or increases the frequency, rate or extent of the directed movement of norepinephrine into a cell. GO:0051624 inhibition of norepinephrine uptake biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051624 inhibition of levarterenol uptake|inhibition of noradrenaline uptake|inhibition of norepinephrine import Any process that prevents the activation of the directed movement of norepinephrine into a cell. GO:0051629 inhibition of epinephrine uptake biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051629 inhibition of epinephrine import|inhibition of adrenaline uptake Any process that prevents the activation of the directed movement of epinephrine into a cell. GO:0051627 negative regulation of epinephrine uptake biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051627 negative regulation of adrenaline uptake|down-regulation of epinephrine uptake|downregulation of epinephrine uptake|down regulation of epinephrine uptake|negative regulation of epinephrine import Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of epinephrine into a cell. GO:0051628 positive regulation of epinephrine uptake biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051628 positive regulation of epinephrine import|stimulation of epinephrine uptake|activation of epinephrine uptake|up-regulation of epinephrine uptake|positive regulation of adrenaline uptake|up regulation of epinephrine uptake|upregulation of epinephrine uptake Any process that activates or increases the frequency, rate or extent of the directed movement of epinephrine into a cell. GO:0036002 pre-mRNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036002 protein-coding primary transcript binding Interacting selectively and non-covalently with pre-messenger RNA (pre-mRNA), an intermediate molecule between DNA and protein that may contain introns and, at least in part, encodes one or more proteins. Introns are removed from pre-mRNA to form a mRNA molecule. GO:0036003 positive regulation of transcription from RNA polymerase II promoter in response to stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036003 Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). GO:0036004 GAF domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036004 Interacting selectively and non-covalently with the GAF domain of a protein. GO:0036005 response to macrophage colony-stimulating factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036005 response to M-CSF|response to macrophage colony-stimulating factor|response to macrophage colony-stimulating factor stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a macrophage colony-stimulating factor stimulus. GO:0036006 cellular response to macrophage colony-stimulating factor stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036006 cellular response to M-CSF stimulus|cellular response to macrophage colony-stimulating factor Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a macrophage colony-stimulating factor stimulus. CHEBI:75381 EC 1.11.1.* (peroxidases) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75381 GO:0036007 scintillon biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036007 A body present in the cytoplasm of some dinoflagellates, which is the source of bioluminescence; emits light on acidification in the presence of oxygen. GO:0036008 sucrose catabolic process to fructose-6-phosphate and glucose-6-phosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036008 MetaCyc:SUCUTIL-PWY The chemical reactions and pathways resulting in the breakdown of sucrose, which proceeds by phosphorylation of sucrose to form sucrose-6-phosphate. The subsequent actions of a hydrolase and a fructokinase generate fructose-6-phosphate and glucose-6-phosphate. CHEBI:75380 EC 1.11.1.6 (catalase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75380 GO:0036009 protein-glutamine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036009 Reactome:R-HSA-6800138 Catalysis of the reaction: S-adenosyl-L-methionine + protein L-glutamine = S-adenosyl-L-homocysteine + protein N-methyl-L-glutamine. CHEBI:75385 1,2-dioleoyl-sn-glycero-3-phospho-(1'-sn-glycerol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75385 GO:0036000 mucocyst biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036000 A small subcellular vesicle, surrounded by a membrane, in the pellicle of ciliate protozoans that discharges a mucus-like secretion. GO:0036001 'de novo' pyridoxal 5'-phosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036001 MetaCyc:PYRIDOXSYN-PWY 'de novo' pyridoxal phosphate biosynthetic process|'de novo' pyridoxal 5'-phosphate biosynthesis|'de novo' PLP biosynthesis|'de novo' pyridoxal 5'-phosphate anabolism|'de novo' pyridoxal 5'-phosphate synthesis|'de novo' pyridoxal 5'-phosphate formation The chemical reactions and pathways resulting in the formation of pyridoxal 5'-phosphate, the active form of vitamin B6, from simpler components. CHEBI:26300 propenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26300 GO:0120057 regulation of small intestinal transit biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120057 regulation of small intestine transit|regulation of small bowel transit Any process that modulates the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine. GO:0120058 positive regulation of small intestinal transit biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120058 positive regulation of small bowel transit|positive regulation of small intestine transit Any process that increases the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine. GO:0120059 negative regulation of small intestinal transit biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120059 negative regulation of small bowel transit|negative regulation of small intestine transit Any process that decreases the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine. CHEBI:16977 L-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16977 CHEBI:16978 leukotriene C4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16978 CHEBI:41945 9-(2-deoxy-5-O-phosphono-beta-L-ribofuranosyl)guanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_41945 GO:0120053 ribitol beta-1,4-xylosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120053 Catalysis of the reaction: UDP-D-xylose + D-ribitol 5-phosphate-R = UDP + beta1,4-xylosyl-D-ribitol 5-phosphate-R. CHEBI:16975 1-acyl-sn-glycerol 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16975 GO:0120054 intestinal motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120054 Contractions of the intestinal tract that include peristalsis (moving contents onward) and non-peristaltic movement (moving contents back and forth). CHEBI:16976 hygromycin B biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16976 GO:0120055 small intestinal transit biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120055 small bowel transit|small intestine transit Migration of ingested material along the length of the small intestine. CHEBI:16973 11-deoxycorticosterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16973 GO:0120056 large intestinal transit biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120056 colon transit|colonic transit|large bowel transit|large intestine transit Migration of ingested material along the length of the large intestine. CHEBI:41941 (3,4-dihydroxyphenyl)acetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_41941 CHEBI:16974 imidazol-4-ylacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16974 CHEBI:16971 benzene-1,2,4-triol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16971 CHEBI:16970 UDP-N-acetylmuramoyl-L-alanyl-D-glutamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16970 CHEBI:26313 propynol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26313 CHEBI:16968 1,8-diazacyclotetradecane-2,9-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16968 GO:0120068 regulation of stomach fundus smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120068 Any process that modulates the frequency, rate or extent of any stomach fundus smooth muscle contraction. GO:0120069 positive regulation of stomach fundus smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120069 Any process that increases the frequency, rate or extent of any stomach fundus smooth muscle contraction. CHEBI:16966 heteroglycan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16966 CHEBI:16967 (Z)-5-oxohex-2-enedioate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16967 GO:0120064 stomach pylorus smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120064 A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the most distal part of the stomach. CHEBI:16964 5-hydroxymethyluracil biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16964 GO:0120065 pyloric antrum smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120065 antrum smooth muscle contraction A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the widest part of the pylorus that is continuous with the body of the stomach. CHEBI:16965 2,3-dihydrogossypetin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16965 CHEBI:16962 cortisone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16962 GO:0120066 pyloric canal smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120066 A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the distal part of the pylorus between the pyloric antrum and the pyloric sphincter. GO:0120067 pyloric sphincter smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120067 A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the narrowest part of the pylorus that separates the stomach from the duodenum. GO:0120060 regulation of gastric emptying biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120060 regulation of small intestine emptying|regulation of small bowel emptying Any process that modulates the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum. CHEBI:16960 ADP-D-ribose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16960 GO:0120061 negative regulation of gastric emptying biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120061 Any process that decreases the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum. CHEBI:16961 monoacylglycerol phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16961 GO:0120062 positive regulation of gastric emptying biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120062 Any process that increases the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum. GO:0120063 stomach smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120063 A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs throughout the length of the stomach. GO:0120079 regulation of microfilament motor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120079 regulation of actin filament motor activity|regulation of myosin ATPase activity|regulation of actin-filament motor activity|regulation of muscle motor activity Any process that modulates the frequency, rate or extent of microfilament motor activity. CHEBI:16999 1-acyl-2-[(S)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16999 GO:0120075 positive regulation of endocardial cushion cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120075 Any process that activates or increases the frequency, rate or extent of endocardial cushion cell differentiation. CHEBI:16997 propane-1,2-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16997 GO:0120076 negative regulation of endocardial cushion cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120076 Any process that stops, prevents, or reduces the frequency, rate or extent of endocardial cushion cell differentiation. CHEBI:16998 D-phenylalanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16998 CHEBI:65932 funalenone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65932 GO:0120077 angiogenic sprout fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120077 blood vessel anastomosis|angiogenic sprout fusion The connection of an angiogenic sprout to another vessel or sprout during the formation of vascular networks by sprouting angiogenesis. CHEBI:16995 oxalic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16995 CHEBI:16996 L-histidinol phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16996 GO:0120078 cell adhesion involved in sprouting angiogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120078 cell adhesion involved in vascular anastomosis|cell adhesion involved in blood vessel anastomosis The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the formation of a blood vessel network. GO:0120071 regulation of pyloric antrum smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120071 Any process that modulates the frequency, rate or extent of any pyloric antrum smooth muscle contraction. CHEBI:16993 2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16993 GO:0120072 positive regulation of pyloric antrum smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120072 Any process that increases the frequency, rate or extent of any pyloric antrum smooth muscle contraction. CHEBI:16994 1-(beta-D-galactosyl)-2-(2-hydroxyacyl)sphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16994 GO:0120073 negative regulation of pyloric antrum smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120073 Any process that decreases the frequency, rate or extent of any pyloric antrum smooth muscle contraction. CHEBI:16991 deoxyribonucleic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16991 GO:0120074 regulation of endocardial cushion cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120074 Any process that modulates the frequency, rate or extent of cell differentiation, the process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cushion cell. CHEBI:16992 2-hydroxy-3-oxopropanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16992 CHEBI:16990 bilirubin IXalpha biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16990 CHEBI:41929 2-deoxy-5-O-phosphono-beta-L-ribofuranosylcytosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_41929 GO:0120070 negative regulation of stomach fundus smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120070 Any process that decreases the frequency, rate or extent of any stomach fundus smooth muscle contraction. CHEBI:16988 D-ribose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16988 CHEBI:16989 2-(carboxymethyl)-5-oxo-2,5-dihydro-3-furoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16989 GO:0120086 (3S)-(+)-asterisca-2(9),6-diene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120086 asterisca-2(9),6-diene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + (3S)-(+)-asterisca-2(9),6-diene. CHEBI:16987 1-piperideine-6-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16987 CHEBI:16984 N-acetylimidazole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16984 CHEBI:16985 5beta-androstane-3,17-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16985 GO:0120082 smooth endoplasmic reticulum cisterna biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120082 A subcompartment of the smooth endoplasmic reticulum consisting of lumenal expansion into a flattened, disc-shaped cavity. CHEBI:16982 (R,R)-butane-2,3-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16982 GO:0120083 rough endoplasmic reticulum cisterna biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120083 A subcompartment of the rough endoplasmic reticulum consisting of lumenal expansion into a flattened, disc-shaped cavity. GO:0120084 endothelial tip cell filopodium assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120084 The assembly of a filopodium, a thin, stiff protrusion extended by the endothelial tip cell of a vascular sprout. CHEBI:16980 geranial biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16980 GO:0120085 transposon integration involved in RNA-mediated transposition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120085 retrotransposon integration Any transposon integration that contributes to a process of RNA-mediated transposition. CHEBI:16981 O-(3-O-D-galactosyl-N-acetyl-beta-D-galactosaminyl)-L-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16981 CHEBI:41917 4-phospho-L-threonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_41917 GO:0120080 negative regulation of microfilament motor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120080 negative regulation of actin filament motor activity|negative regulation of actin-filament motor activity|negative regulation of muscle motor activity|negative regulation of myosin ATPase activity Any process that stops, prevents or reduces the frequency, rate or extent of microfilament motor activity. GO:0120081 positive regulation of microfilament motor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120081 positive regulation of myosin ATPase activity|positive regulation of muscle motor activity|positive regulation of actin-filament motor activity|positive regulation of actin filament motor activity Any process that activates or increases the frequency, rate or extent of microfilament motor activity. GO:0120017 ceramide transfer activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120017 ceramide carrier activity|intermembrane ceramide transfer activity|ceramide transporter activity Removes a ceramide from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. CHEBI:16939 3-amino-3-(4-hydroxyphenyl)propanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16939 CHEBI:90906 protodeoxyviolaceinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90906 GO:0120018 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0120018 CHEBI:90907 protodeoxyviolaceinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90907 GO:0120019 phosphatidylcholine transfer activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120019 phosphatidylcholine carrier activity|intermembrane phosphatidylcholine transfer activity Removes phosphatidylcholine from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. CHEBI:16937 5,6-dihydroxy-3-methylquinolin-2(1H)-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16937 CHEBI:90909 deoxyviolaceinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90909 CHEBI:16938 6-O-phosphono-D-glucono-1,5-lactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16938 GO:0120013 lipid transfer activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120013 lipid carrier activity|intermembrane lipid transfer activity Removes a lipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. This results in intermembrane transfer of lipids. CHEBI:16935 L-rhamnofuranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16935 GO:0120014 phospholipid transfer activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120014 intermembrane phospholipid transfer activity|phospholipid carrier activity Removes a phospholipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. CHEBI:90915 aurachin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90915 CHEBI:16933 ergosterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16933 GO:0120015 sterol transfer activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120015 sterol carrier activity|intermembrane sterol transfer activity Removes a sterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. GO:0120016 sphingolipid transfer activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120016 intermembrane sphingolipid transfer activity|sphingolipid carrier activity Removes a sphingolipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. CHEBI:16934 3-cyano-L-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16934 CHEBI:16931 trans-cyclohexane-1,2-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16931 GO:0120010 intermembrane phospholipid transfer biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120010 The transport of phospholipids between membranes in which a phospholipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. CHEBI:90910 deoxyviolaceinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90910 CHEBI:89929 glycoursodeoxycholic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_89929 CHEBI:16932 UDP-N-acetylmuramoyl-L-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16932 GO:0120011 intermembrane sterol transfer biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120011 The transport of sterols between membranes in which a sterol molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs). GO:0120012 intermembrane sphingolipid transfer biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120012 The transport of sphingolipids between membranes in which a sphingolipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs). GO:0120028 negative regulation of osmosensory signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120028 Any process that stops, prevents or reduces the frequency, rate or extent of osmosensory signaling pathway. GO:0120029 proton export across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120029 hydrogen ion export across plasma membrane|proton export across plasma membrane|proton export from cell|hydrogen ion export from cell The directed movement of hydrogen ions (protons) from inside a cell, across the plasma membrane and into the extracellular region. CHEBI:16929 sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16929 CHEBI:16927 L-saccharopine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16927 CHEBI:16924 5-oxo-D-proline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16924 GO:0120024 glucagon-like peptide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120024 Interacting selectively and non-covalently with glucagon-like peptide, a antihyperglycemic hormone. Glucagon-like peptide is derived from the glucagon gene produced by pancreatic alpha cells. CHEBI:90902 4-hydroxyprotoasukamycin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90902 GO:0120025 plasma membrane bounded cell projection biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120025 A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon. CHEBI:90903 asperlicin E biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90903 CHEBI:16925 6-phospho-5-dehydro-2-deoxy-D-gluconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16925 CHEBI:90904 asperlicin C biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90904 GO:0120026 host cell uropod biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120026 host cell uropodium A host cell membrane projection with related cytoskeletal components at the trailing edge of a cell in the process of migrating or being activated, found on the opposite side of the cell from the leading edge or immunological synapse, respectively. CHEBI:16923 N-formyl-L-aspartate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16923 GO:0120027 regulation of osmosensory signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120027 Any process that modulates the frequency, rate or extent of osmosensory signaling pathway. GO:0120020 cholesterol transfer activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120020 Reactome:R-HSA-265443|Reactome:R-HSA-5682111|Reactome:R-HSA-265545|Reactome:R-HSA-1454928|Reactome:R-HSA-266082|Reactome:R-HSA-216723|Reactome:R-HSA-8951850 cholesterol carrier activity|intermembrane cholesterol transfer activity|cholesterol transporter activity Removes cholesterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. GO:0120021 oxysterol transfer activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120021 oxysterol carrier activity|intermembrane oxysterol transfer activity Removes oxysterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. GO:0120022 glucagon binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120022 Interacting selectively and non-covalently with glucagon, a polypeptide hormone involved in glucose response. It is produced by pancreatic alpha cells and raises the concentration of glucose in the blood. CHEBI:90900 violaceinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90900 GO:0120023 somatostatin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120023 Interacting selectively and non-covalently with somatostatin, a polypeptide hormone involved in regulating pancreatic alpha and pancreatic beta cells and controlling growth hormone secretion as well as many other functions. Somatostatin is produced by several cell types including pancreatic delta cells. There are several different mature forms of somatostatin. CHEBI:90901 protoasukamycin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90901 GO:0120039 plasma membrane bounded cell projection morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120039 The process in which the anatomical structures of a plasma membrane bounded cell projection are generated and organized. CHEBI:16959 albendazole S-oxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16959 GO:0120035 regulation of plasma membrane bounded cell projection organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120035 Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections. CHEBI:16957 deacetoxyvindoline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16957 GO:0120036 plasma membrane bounded cell projection organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120036 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon. CHEBI:16958 beta-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16958 CHEBI:16955 GDP-4-dehydro-6-deoxy-alpha-D-mannose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16955 GO:0120038 obsolete plasma membrane bounded cell projection part biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120038 OBSOLETE. Any constituent part of a plasma membrane bounded cell projection, a prolongation or process extending from a cell, e.g. a cilium or axon. GO:0120031 plasma membrane bounded cell projection assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120031 eupodium Formation of a prolongation or process extending and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon. CHEBI:16953 N-acetyl-L-aspartate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16953 GO:0120032 regulation of plasma membrane bounded cell projection assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120032 Any process that modulates the rate, frequency, or extent of plasma membrane bounded cell projection assembly. CHEBI:16954 vitexin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16954 GO:0120033 negative regulation of plasma membrane bounded cell projection assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120033 Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane bounded cell projection assembly. GO:0120034 positive regulation of plasma membrane bounded cell projection assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120034 Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly. CHEBI:16952 5-hydroxymethyldeoxycytidylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16952 CHEBI:16950 2-dehydro-3-deoxy-L-fuconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16950 GO:0120030 positive regulation of cilium beat frequency involved in ciliary motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120030 Any process that activates or increases the frequency of cilium beating involved in ciliary motility. CHEBI:75305 glutamine hydroxamate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75305 CHEBI:75306 2-heptyl-4-hydroxyquinoline biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75306 CHEBI:75304 1-palmitoyl-2-myristoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75304 CHEBI:75309 aklanonate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75309 CHEBI:75308 19-oxotestosterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75308 CHEBI:90917 A-type aurachin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90917 CHEBI:90918 C-type aurachin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90918 GO:0120046 regulation of protein localization to medial cortical node biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120046 Any process that modulates the frequency, rate or extent of protein localization to a medial cortical node. CHEBI:16946 L-kynurenine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16946 CHEBI:16947 citrate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16947 GO:0120047 positive regulation of protein localization to medial cortical node biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120047 Any process that activates or increases the frequency, rate or extent of protein localization to a medial cortical node. GO:0120048 U6 snRNA (adenine-(43)-N(6))-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120048 Catalysis of the reaction: S-adenosyl-L-methionine + adenine(43) in U6 snRNA = S-adenosyl-L-homocysteine + N(6)-methyladenine(43) in U6 snRNA. CHEBI:16944 L-2-amino-3-oxobutanoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16944 GO:0120049 snRNA (adenine-N6)-methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120049 The posttranscriptional N6-methylation of an adenine residue in an snRNA molecule. CHEBI:16945 scytalone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16945 GO:0120042 negative regulation of macrophage proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120042 Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage proliferation. CHEBI:90920 EC 1.8.5.* (oxidoreductase acting on sulfur group donors, quinone or similar as acceptor) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90920 CHEBI:16942 lipid X biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16942 GO:0120043 stereocilium shaft biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120043 The shaft comprises the majority of the length of the stereocilium. This region is notable for the extreme stability of actin filaments, which are highly crosslinked into a parallel bundle. CHEBI:90921 EC 1.8.5.4 (sulfide:quinone reductase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90921 CHEBI:16943 (R)-2,4-dihydroxy-3-oxobutanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16943 GO:0120044 stereocilium base biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120044 stereocilium taper The tapered base of the stereocilium adjacent to where it joins the hair cell body. This region contains a rootlet comprised of bundled actin filaments which spans the joint and stabilizes the stereocilium. GO:0120045 stereocilium maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120045 The organization process that preserves a stereocilium in a stable functional or structural state. CHEBI:16941 cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16941 GO:0120040 regulation of macrophage proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120040 Any process that modulates the frequency, rate or extent of macrophage proliferation. GO:0120041 positive regulation of macrophage proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120041 Any process that activates or increases the frequency, rate or extent of macrophage proliferation. CHEBI:75301 1-palmitoyl-2-hexanoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75301 CHEBI:75302 1-palmitoyl-2-capryloyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75302 CHEBI:75300 1-palmitoyl-2-decanoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75300 GO:0002863 positive regulation of inflammatory response to antigenic stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002863 stimulation of inflammatory response to antigenic stimulus|up-regulation of inflammatory response to antigenic stimulus|upregulation of inflammatory response to antigenic stimulus|up regulation of inflammatory response to antigenic stimulus|activation of inflammatory response to antigenic stimulus Any process that activates or increases the frequency, rate, or extent of an inflammatory response to an antigenic stimulus. CHEBI:51349 polyamine macromolecule biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51349 GO:0002864 regulation of acute inflammatory response to antigenic stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002864 Any process that modulates the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus. GO:0002865 negative regulation of acute inflammatory response to antigenic stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002865 inhibition of acute inflammatory response to antigenic stimulus|down regulation of acute inflammatory response to antigenic stimulus|downregulation of acute inflammatory response to antigenic stimulus|down-regulation of acute inflammatory response to antigenic stimulus Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus. GO:0002866 positive regulation of acute inflammatory response to antigenic stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002866 up-regulation of acute inflammatory response to antigenic stimulus|upregulation of acute inflammatory response to antigenic stimulus|up regulation of acute inflammatory response to antigenic stimulus|activation of acute inflammatory response to antigenic stimulus|stimulation of acute inflammatory response to antigenic stimulus Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus. CHEBI:26389 purine deoxyribonucleoside triphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26389 GO:0002860 positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002860 up regulation of natural killer cell mediated cytotoxicity directed against tumor cell target|upregulation of natural killer cell mediated cytotoxicity directed against tumor cell target|stimulation of natural killer cell mediated cytotoxicity directed against tumor cell target|activation of natural killer cell mediated cytotoxicity directed against tumor cell target|up-regulation of natural killer cell mediated cytotoxicity directed against tumor cell target Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target. GO:0002861 regulation of inflammatory response to antigenic stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002861 Any process that modulates the frequency, rate, or extent of an inflammatory response to an antigenic stimulus. GO:0002862 negative regulation of inflammatory response to antigenic stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002862 down-regulation of inflammatory response to antigenic stimulus|inhibition of inflammatory response to antigenic stimulus|down regulation of inflammatory response to antigenic stimulus|downregulation of inflammatory response to antigenic stimulus Any process that stops, prevents, or reduces the frequency, rate, or extent of an inflammatory response to an antigenic stimulus. CHEBI:26385 purine alkaloid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26385 GO:0061160 regulation of establishment of bipolar cell polarity regulating cell shape biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061160 Any process that modulates the rate, frequency or extent of the establishment of bipolar cell polarity that contributes to the shape of a cell. CHEBI:26386 purine nucleobase biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_26386 GO:0061161 positive regulation of establishment of bipolar cell polarity regulating cell shape biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061161 Any process that increases the rate, frequency or extent of the establishment of bipolar cell polarity that regulates the shape of a cell. CHEBI:26387 purine 2'-deoxyribonucleoside diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26387 CHEBI:26388 purine 2'-deoxyribonucleoside monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26388 GO:0061162 establishment of monopolar cell polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061162 The specification and formation of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis. CHEBI:26381 p-menth-4(8)-en-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_26381 GO:0061163 endoplasmic reticulum polarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061163 The endoplasmic reticulum organization process that results in the structure of the endoplasmic reticulum being oriented in the cell. GO:0061164 transitional endoplasmic reticulum polarization at cell division site biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061164 The endoplasmic reticulum polarization process that results in the structure being polarized at the site of future cell division. GO:0061165 endoplasmic reticulum localization involved in endoplasmic reticulum polarization at cell division site biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061165 endoplasmic reticulum localisation involved in endoplasmic reticulum polarization at cell division site|ER localization involved in ER polarization at cell division site The process in which endoplasmic reticulum is transiently localized to the site where a cell will divide. CHEBI:26384 pullulans biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26384 GO:0061166 establishment of endoplasmic reticulum localization involved in endoplasmic reticulum polarization at cell division site biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061166 establishment of endoplasmic reticulum localisation involved in endoplasmic reticulum polarization at cell division site The directed movement of the endoplasmic reticulum to the site where a cell will divide. GO:0061167 maintenance of endoplasmic reticulum location involved in endoplasmic reticulum polarization at cell division site biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061167 The process in which the endoplasmic reticulum is maintained at the site of cell division and is prevented from moving elsewhere. GO:0061168 regulation of hair follicle placode formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061168 Any process that modulates the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud. GO:0061169 positive regulation of hair placode formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061169 Any process that increases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud. CHEBI:26390 purine 2'-deoxyribonucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26390 CHEBI:26391 purine nucleoside diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26391 CHEBI:51341 pristanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51341 GO:0002867 regulation of B cell deletion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002867 regulation of B-cell deletion|regulation of B lymphocyte deletion|regulation of B-lymphocyte deletion Any process that modulates the frequency, rate, or extent of B cell deletion. GO:0002868 negative regulation of B cell deletion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002868 down-regulation of B cell deletion|inhibition of B cell deletion|negative regulation of B-lymphocyte deletion|negative regulation of B-cell deletion|down regulation of B cell deletion|downregulation of B cell deletion|negative regulation of B lymphocyte deletion Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell deletion. GO:0002869 positive regulation of B cell deletion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002869 stimulation of B cell deletion|positive regulation of B-lymphocyte deletion|up-regulation of B cell deletion|positive regulation of B-cell deletion|upregulation of B cell deletion|positive regulation of B lymphocyte deletion|up regulation of B cell deletion|activation of B cell deletion Any process that activates or increases the frequency, rate, or extent of B cell deletion. CHEBI:51340 pristanic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51340 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002874 Any process that modulates the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus. CHEBI:51339 adamantanes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51339 GO:0002875 negative regulation of chronic inflammatory response to antigenic stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002875 downregulation of chronic inflammatory response to antigenic stimulus|down-regulation of chronic inflammatory response to antigenic stimulus|inhibition of chronic inflammatory response to antigenic stimulus|down regulation of chronic inflammatory response to antigenic stimulus Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus. GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002876 up regulation of chronic inflammatory response to antigenic stimulus|activation of chronic inflammatory response to antigenic stimulus|stimulation of chronic inflammatory response to antigenic stimulus|up-regulation of chronic inflammatory response to antigenic stimulus|upregulation of chronic inflammatory response to antigenic stimulus Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus. GO:0002877 regulation of acute inflammatory response to non-antigenic stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002877 Any process that modulates the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus. GO:0002870 T cell anergy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002870 T-lymphocyte anergy|T-cell anergy|T lymphocyte anergy Any process contributing to anergy in T cells, a state of functional inactivation which is part of T cell tolerance induction. CHEBI:51334 SO-thioperoxol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_51334 GO:0002871 regulation of natural killer cell tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002871 regulation of NK cell tolerance induction Any process that modulates the frequency, rate, or extent of natural killer cell tolerance induction. GO:0002872 negative regulation of natural killer cell tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002872 down regulation of natural killer cell tolerance induction|downregulation of natural killer cell tolerance induction|negative regulation of NK cell tolerance induction|down-regulation of natural killer cell tolerance induction|inhibition of natural killer cell tolerance induction Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell tolerance induction. GO:0002873 positive regulation of natural killer cell tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002873 positive regulation of NK cell tolerance induction|up regulation of natural killer cell tolerance induction|activation of natural killer cell tolerance induction|stimulation of natural killer cell tolerance induction|up-regulation of natural killer cell tolerance induction|upregulation of natural killer cell tolerance induction Any process that activates or increases the frequency, rate, or extent of natural killer cell tolerance induction. CHEBI:51337 organic sulfate salt biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51337 CHEBI:26396 purine ribonucleoside diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26396 CHEBI:26397 purine ribonucleoside monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26397 GO:0061150 renal system segmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061150 urinary tract segmentation The regionalization process that divides an the renal system into a series of segments along its proximal/distal axis. CHEBI:26398 purine ribonucleoside triphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26398 GO:0061151 BMP signaling pathway involved in renal system segmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061151 BMP signalling pathway involved in renal system segmentation A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the segmentation of the renal system. CHEBI:26399 purine ribonucleoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_26399 GO:0061152 trachea submucosa development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061152 The progression of the trachea submucosa over time from its formation to the mature structure. The trachea submucosa is made up of the glands and elastic tissue that lie under the mucosa in the trachea. CHEBI:26392 purine nucleoside monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26392 GO:0061153 trachea gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061153 The progression of a trachea gland over time, from its formation to the mature structure. Trachea glands are found under the mucus of the trachea and secrete mucus, and agents that help protect the lung from injury and infection. CHEBI:26393 purine nucleoside triphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26393 GO:0061154 endothelial tube morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061154 The process in which the anatomical structures of a tube are generated and organized from an endothelium. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells. CHEBI:26394 purine nucleoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26394 GO:0061155 pulmonary artery endothelial tube morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061155 The process in which the anatomical structures of a tube are generated and organized from the pulmonary artery endothelium. An pulmonary artery endothelium is an epithelium that lines the pulmonary artery. CHEBI:26395 purine nucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26395 GO:0061156 pulmonary artery morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061156 The process in which the anatomical structures of the pulmonary artery are generated and organized. The pulmonary artery is the artery that carries blood from the heart to the lungs. GO:0061157 mRNA destabilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061157 Any process that decreases the stability of an mRNA molecule, making it more vulnerable to degradative processes. Messenger RNA is the intermediate molecule between DNA and protein. It includes UTR and coding sequences. It does not contain introns. GO:0061158 3'-UTR-mediated mRNA destabilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061158 An mRNA destabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA. GO:0061159 establishment of bipolar cell polarity involved in cell morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061159 The specification and formation of bipolar intracellular organization or cell growth patterns that contribute to cell morphogenesis. Bipolar organization is the organization that is a mirror image along an axis from a plane. CHEBI:9533 thiamine(1+) monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_9533 CHEBI:9534 thiamine(1+) triphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_9534 CHEBI:51333 sulfenic acid derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51333 GO:0002878 negative regulation of acute inflammatory response to non-antigenic stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002878 down regulation of acute inflammatory response to non-antigenic stimulus|downregulation of acute inflammatory response to non-antigenic stimulus|down-regulation of acute inflammatory response to non-antigenic stimulus|inhibition of acute inflammatory response to non-antigenic stimulus Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus. GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002879 up regulation of acute inflammatory response to non-antigenic stimulus|activation of acute inflammatory response to non-antigenic stimulus|stimulation of acute inflammatory response to non-antigenic stimulus|up-regulation of acute inflammatory response to non-antigenic stimulus|upregulation of acute inflammatory response to non-antigenic stimulus Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus. CHEBI:9532 thiamine(1+) diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_9532 GO:0002841 negative regulation of T cell mediated immune response to tumor cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002841 negative regulation of T-lymphocyte mediated immune response to tumor cell|negative regulation of T-cell mediated immune response to tumor cell|down regulation of T cell mediated immune response to tumor cell|downregulation of T cell mediated immune response to tumor cell|negative regulation of T lymphocyte mediated immune response to tumor cell|negative regulation of T cell mediated immune response to tumour cell|down-regulation of T cell mediated immune response to tumor cell|inhibition of T cell mediated immune response to tumor cell Any process that stops, prevents, or reduces the frequency, rate, or extent of a T cell mediated immune response to tumor cell. GO:0002842 positive regulation of T cell mediated immune response to tumor cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002842 up-regulation of T cell mediated immune response to tumor cell|positive regulation of T-cell mediated immune response to tumor cell|upregulation of T cell mediated immune response to tumor cell|positive regulation of T lymphocyte mediated immune response to tumor cell|up regulation of T cell mediated immune response to tumor cell|activation of T cell mediated immune response to tumor cell|stimulation of T cell mediated immune response to tumor cell|positive regulation of T cell mediated immune response to tumour cell|positive regulation of T-lymphocyte mediated immune response to tumor cell Any process that activates or increases the frequency, rate, or extent of a T cell mediated immune response to tumor cell. GO:0002843 regulation of tolerance induction to tumor cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002843 regulation of tolerance induction to tumour cell Any process that modulates the frequency, rate, or extent of tolerance induction to tumor cell. GO:0002844 negative regulation of tolerance induction to tumor cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002844 downregulation of tolerance induction to tumor cell|negative regulation of tolerance induction to tumour cell|down-regulation of tolerance induction to tumor cell|inhibition of tolerance induction to tumor cell|down regulation of tolerance induction to tumor cell Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to tumor cell. CHEBI:51323 cinchona alkaloid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51323 CHEBI:51324 vinylarene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51324 CHEBI:26369 psoralens biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26369 GO:0002840 regulation of T cell mediated immune response to tumor cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002840 regulation of T cell mediated immune response to tumour cell|regulation of T lymphocyte mediated immune response to tumor cell|regulation of T-lymphocyte mediated immune response to tumor cell|regulation of T-cell mediated immune response to tumor cell Any process that modulates the frequency, rate, or extent of a T cell mediated immune response to tumor cell. GO:0061180 mammary gland epithelium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061180 breast epithelium development The process whose specific outcome is the progression of the mammary gland epithelium over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. GO:0061181 regulation of chondrocyte development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061181 Any process that modulates the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate. GO:0061182 negative regulation of chondrocyte development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061182 Any process that decreases the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate. GO:0061183 regulation of dermatome development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061183 Any process that modulates the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. GO:0061184 positive regulation of dermatome development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061184 Any process that increases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. CHEBI:26366 pseudouridines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26366 GO:0061185 negative regulation of dermatome development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061185 Any process that decreases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. GO:0061186 negative regulation of silent mating-type cassette heterochromatin assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061186 negative regulation of chromatin silencing at silent mating-type cassette Any process that decreases the frequency, rate, or extent of chromatin silencing at silent mating-type cassette. Chromatin silencing at silent mating-type cassette is the repression of transcription at silent mating-type loci by altering the structure of chromatin. CHEBI:26361 protoporphyrins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26361 GO:0061187 regulation of ribosomal DNA heterochromatin assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061187 regulation of chromatin silencing at rDNA Any process that modulates the rate, frequency, or extent of the repression of assembly of rDNA heterochromatin. GO:0061188 negative regulation of ribosomal DNA heterochromatin assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061188 negative regulation of chromatin silencing at rDNA Any process that decreases the rate, frequency, or extent of the repression of assembly of rDNA heterochromatin. GO:0061189 positive regulation of sclerotome development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061189 Any process that increases the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra. GO:0002849 regulation of peripheral T cell tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002849 Any process that modulates the frequency, rate, or extent of peripheral T cell tolerance induction. GO:0002845 positive regulation of tolerance induction to tumor cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002845 up regulation of tolerance induction to tumor cell|activation of tolerance induction to tumor cell|stimulation of tolerance induction to tumor cell|positive regulation of tolerance induction to tumour cell|up-regulation of tolerance induction to tumor cell|upregulation of tolerance induction to tumor cell Any process that activates or increases the frequency, rate, or extent of tolerance induction to tumor cell. GO:0002846 regulation of T cell tolerance induction to tumor cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002846 Any process that modulates the frequency, rate, or extent of T cell tolerance induction to tumor cell. GO:0002847 negative regulation of T cell tolerance induction to tumor cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002847 down-regulation of T cell tolerance induction to tumor cell|downregulation of T cell tolerance induction to tumor cell|down regulation of T cell tolerance induction to tumor cell|inhibition of T cell tolerance induction to tumor cell Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell tolerance induction to tumor cell. GO:0002848 positive regulation of T cell tolerance induction to tumor cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002848 up regulation of T cell tolerance induction to tumor cell|upregulation of T cell tolerance induction to tumor cell|stimulation of T cell tolerance induction to tumor cell|up-regulation of T cell tolerance induction to tumor cell|activation of T cell tolerance induction to tumor cell Any process that activates or increases the frequency, rate, or extent of T cell tolerance induction to tumor cell. GO:0002852 regulation of T cell mediated cytotoxicity directed against tumor cell target biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002852 Any process that modulates the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target. CHEBI:51316 haloethene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51316 GO:0002853 negative regulation of T cell mediated cytotoxicity directed against tumor cell target biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002853 inhibition of T cell mediated cytotoxicity directed against tumor cell target|down regulation of T cell mediated cytotoxicity directed against tumor cell target|downregulation of T cell mediated cytotoxicity directed against tumor cell target|down-regulation of T cell mediated cytotoxicity directed against tumor cell target Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target. GO:0002854 positive regulation of T cell mediated cytotoxicity directed against tumor cell target biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002854 up-regulation of T cell mediated cytotoxicity directed against tumor cell target|upregulation of T cell mediated cytotoxicity directed against tumor cell target|up regulation of T cell mediated cytotoxicity directed against tumor cell target|activation of T cell mediated cytotoxicity directed against tumor cell target|stimulation of T cell mediated cytotoxicity directed against tumor cell target Any process that activates or increases the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target. GO:0002855 regulation of natural killer cell mediated immune response to tumor cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002855 Any process that modulates the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell. CHEBI:51312 dehypoxanthine futalosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51312 GO:0002850 negative regulation of peripheral T cell tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002850 inhibition of peripheral T cell tolerance induction|down regulation of peripheral T cell tolerance induction|downregulation of peripheral T cell tolerance induction|down-regulation of peripheral T cell tolerance induction Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral T cell tolerance induction. GO:0002851 positive regulation of peripheral T cell tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002851 up-regulation of peripheral T cell tolerance induction|upregulation of peripheral T cell tolerance induction|up regulation of peripheral T cell tolerance induction|activation of peripheral T cell tolerance induction|stimulation of peripheral T cell tolerance induction Any process that activates or increases the frequency, rate, or extent of peripheral T cell tolerance induction. GO:0061170 negative regulation of hair follicle placode formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061170 Any process that decreases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud. CHEBI:26374 pterin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26374 GO:0061171 establishment of bipolar cell polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061171 The specification and formation of bipolar intracellular organization or cell growth patterns. Bipolar organization is the organization that is a mirror image along an axis from a plane. CHEBI:26375 pterins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26375 GO:0061172 regulation of establishment of bipolar cell polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061172 Any process that modulates the rate, frequency or extent of the establishment of bipolar cell polarity. Bipolar organization is the organization that is a mirror image along an axis from a plane. CHEBI:26377 pterocarpans biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_26377 GO:0061173 positive regulation of establishment of bipolar cell polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061173 Any process that increases the rate, frequency or extent of the establishment of bipolar cell polarity. GO:0061174 type I terminal bouton biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061174 type I terminal button Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters that will induce the contraction of muscle. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it. GO:0061175 type II terminal bouton biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061175 type II terminal button Terminal inflated portion of the axon of a non-glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters at a regulatory synapse. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it. GO:0061176 type Ib terminal bouton biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061176 type Ib terminal button Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary for the tonic release neurotransmitters that will induce the contraction of muscle. Type Ib terminal boutons are larger than type Is terminal boutons. GO:0061177 type Is terminal bouton biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061177 type Is terminal button Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary for the phasic release neurotransmitters that will induce the contraction of muscle. Type Is terminal boutons are smaller than type Ib terminal boutons. CHEBI:26373 pteridines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26373 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061178 regulation of insulin secretion in response to glucose Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose. CHEBI:9519 thebaine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_9519 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061179 negative regulation of insulin secretion involved in cellular response to glucose|negative regulation of insulin secretion in response to glucose Any process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose. CHEBI:9516 thapsigargin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_9516 CHEBI:51310 futalosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51310 GO:0002856 negative regulation of natural killer cell mediated immune response to tumor cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002856 downregulation of natural killer cell mediated immune response to tumor cell|down regulation of natural killer cell mediated immune response to tumor cell|inhibition of natural killer cell mediated immune response to tumor cell|down-regulation of natural killer cell mediated immune response to tumor cell Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell. GO:0002857 positive regulation of natural killer cell mediated immune response to tumor cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002857 up regulation of natural killer cell mediated immune response to tumor cell|upregulation of natural killer cell mediated immune response to tumor cell|stimulation of natural killer cell mediated immune response to tumor cell|activation of natural killer cell mediated immune response to tumor cell|up-regulation of natural killer cell mediated immune response to tumor cell Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell. GO:0002858 regulation of natural killer cell mediated cytotoxicity directed against tumor cell target biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002858 Any process that modulates the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target. GO:0002859 negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002859 downregulation of natural killer cell mediated cytotoxicity directed against tumor cell target|down regulation of natural killer cell mediated cytotoxicity directed against tumor cell target|inhibition of natural killer cell mediated cytotoxicity directed against tumor cell target|down-regulation of natural killer cell mediated cytotoxicity directed against tumor cell target Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target. CHEBI:26349 proteochondroitin sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26349 GO:0002820 negative regulation of adaptive immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002820 down-regulation of adaptive immune response|downregulation of adaptive immune response|down regulation of adaptive immune response|inhibition of adaptive immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response. GO:0002821 positive regulation of adaptive immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002821 up regulation of adaptive immune response|upregulation of adaptive immune response|stimulation of adaptive immune response|up-regulation of adaptive immune response|activation of adaptive immune response Any process that activates or increases the frequency, rate, or extent of an adaptive immune response. CHEBI:51307 diester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51307 CHEBI:51308 dinitrile biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51308 GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002822 Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata. CHEBI:26345 prostaglandins I biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_26345 CHEBI:26346 prostaglandins J biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_26346 CHEBI:26347 prostanoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26347 CHEBI:26348 prosthetic group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26348 CHEBI:41983 4'-epidoxorubicinium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_41983 CHEBI:26343 prostaglandins G biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_26343 CHEBI:26344 prostaglandins H biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_26344 CHEBI:51309 N(2)-succinyl-L-citrulline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51309 CHEBI:26340 prostaglandins F biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_26340 GO:0120097 glycosylphosphatidylinositol-mannosyltransferase II complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120097 IntAct:EBI-16398134 GPI-MT-I complex A protein complex that is involved in the transfer of the second mannose to the glycosylphosphatidylinositol (GPI) during GPI precursor assembly. In yeast S. cerevisiae this complex consists of GPI18p and PGA1p. GO:0120098 procentriole biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120098 A cellular structure that is the site of a developing centriole, which will become a microtubule organizing center. During the canonical pathway of centriole duplication that occurs during the cell division cycle, procentrioles grow at the proximal ends of both mother and daughter centrioles. In the newly divided cells, the original mother and daughter centrioles become mother centrioles while the procentrioles become the new daughter centrioles. Procentrioles can also arise from de novo pathways that occur in multiciliated cells. In ciliated epithelial cells, numerous procentrioles arise form electron dense material referred to as fibrous granules and deuterosomes. The pathway of procentriole formation in multiciliated protists appears to be similar to that in mammalian multiciliated epithelium. In sperm of primative land plants, multiple procentrioles are formed from a blepharoplast giving rise to multicilated sperm cells. GO:0120099 procentriole replication complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120099 IntAct:EBI-15189349|IntAct:EBI-15188467|IntAct:EBI-15316456 A protein complex that acts as a chaperone or scaffold for centriolar proteins during the maturation of the procentriole. Some of its members may become integrated into the growing centriole. Examples are the CPAP(CENPJ)-STIL complex, CEP192-PLK4 complex or CEP152-PLK4 complex in vertebrates. GO:0120093 regulation of peptidyl-lysine crotonylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120093 Any process that modulates the frequency, rate or extent of crotonylation of a lysine residue in a protein. GO:0002827 positive regulation of T-helper 1 type immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002827 upregulation of T-helper 1 type immune response|up regulation of T-helper 1 type immune response|activation of T-helper 1 type immune response|stimulation of T-helper 1 type immune response|up-regulation of T-helper 1 type immune response Any process that activates or increases the frequency, rate, or extent of a T-helper 1 type immune response. GO:0120094 negative regulation of peptidyl-lysine crotonylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120094 Any process that stops or reduces the rate of crotonylation of a lysine residue in a protein. GO:0002828 regulation of type 2 immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002828 regulation of T-helper 2 type immune response|regulation of Th2 immune response Any process that modulates the frequency, rate, or extent of a type 2 immune response. GO:0002829 negative regulation of type 2 immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002829 inhibition of type 2 immune response|negative regulation of T-helper 2 type immune response|negative regulation of Th2 immune response|down-regulation of type 2 immune response|downregulation of type 2 immune response|down regulation of type 2 immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of a type 2 immune response. GO:0120095 vacuole-isolation membrane contact site biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120095 vacuole-phagophore contact site|vacuole-IM contact site|VICS An organelle membrane contact site formed at the junction of the vacuolar membrane and the isolation membrane or phagophore in response to starvation or other stresses, leading to the formation of the autophagosome. GO:0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002823 Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata. GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002824 Any process that activates or increases the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata. GO:0120091 jasmonic acid hydrolase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120091 2-oxoglutarate dioxygenase Catalyzes the hydroxylation of jasmonic acid to 12OH-jasmonic acid. GO:0002825 regulation of T-helper 1 type immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002825 Any process that modulates the frequency, rate, or extent of a T-helper 1 type immune response. GO:0120092 crotonyl-CoA hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120092 RHEA:45584 Catalysis of the reaction: Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine. GO:0002826 negative regulation of T-helper 1 type immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002826 down regulation of T-helper 1 type immune response|downregulation of T-helper 1 type immune response|down-regulation of T-helper 1 type immune response|inhibition of T-helper 1 type immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of a T-helper 1 type immune response. GO:0002830 positive regulation of type 2 immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002830 up regulation of type 2 immune response|positive regulation of T-helper 2 type immune response|upregulation of type 2 immune response|positive regulation of Th2 immune response|stimulation of type 2 immune response|up-regulation of type 2 immune response|activation of type 2 immune response Any process that activates or increases the frequency, rate, or extent of a type 2 immune response. GO:0002831 regulation of response to biotic stimulus biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0002831 Any process that modulates the frequency, rate, or extent of a response to biotic stimulus. GO:0002832 negative regulation of response to biotic stimulus biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0002832 down regulation of response to biotic stimulus|downregulation of response to biotic stimulus|down-regulation of response to biotic stimulus|inhibition of response to biotic stimulus Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus. GO:0002833 positive regulation of response to biotic stimulus biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0002833 upregulation of response to biotic stimulus|up regulation of response to biotic stimulus|activation of response to biotic stimulus|stimulation of response to biotic stimulus|up-regulation of response to biotic stimulus Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus. GO:0061190 regulation of sclerotome development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061190 Any process that modulates the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra. GO:0061191 positive regulation of vacuole fusion, non-autophagic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061191 Any process that increases the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole. GO:0061192 negative regulation of vacuole fusion, non-autophagic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061192 Any process that decreases the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole. GO:0061193 taste bud development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061193 The progression of the taste bud over time, from its formation to the mature state. The taste bud is a specialized area of the tongue that contains taste receptors. GO:0061194 taste bud morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061194 The process in which the anatomical structures of the taste bud are generated and organized. The taste bud is a specialized area of the tongue that contains taste receptors. CHEBI:26354 protochlorophyllides biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26354 GO:0061195 taste bud formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061195 The developmental process pertaining to the initial formation of the taste bud from unspecified parts. The taste bud is a specialized area of the tongue that contains taste receptors. CHEBI:26355 heme b biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26355 GO:0061196 fungiform papilla development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061196 The progression of the fungiform papilla over time, from its formation to the mature structure. The fungiform papilla is a mushroom-shaped papilla of the tongue. GO:0061197 fungiform papilla morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061197 The process in which the anatomical structures of the fungiform papilla are generated and organized. The fungiform papilla is a mushroom-shaped papilla of the tongue. GO:0061198 fungiform papilla formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061198 The developmental process pertaining to the initial formation of a spongiform papilla from unspecified parts. The fungiform papilla is a mushroom-shaped papilla of the tongue. GO:0061199 striated muscle contraction involved in embryonic body morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061199 The process in which force is generated within striated embryonic muscle tissue, resulting in a contraction of the muscle that contributes to the formation of an embryo's characteristic body morphology. CHEBI:41977 daunorubicin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_41977 CHEBI:9577 (-)-alpha-thujone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_9577 GO:0002838 negative regulation of immune response to tumor cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002838 down regulation of immune response to tumor cell|downregulation of immune response to tumor cell|negative regulation of immune response to tumour cell|down-regulation of immune response to tumor cell|inhibition of immune response to tumor cell Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune response to tumor cell. CHEBI:9578 (-)-thujopsene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_9578 GO:0002839 positive regulation of immune response to tumor cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002839 up regulation of immune response to tumor cell|activation of immune response to tumor cell|positive regulation of immune response to tumour cell|stimulation of immune response to tumor cell|up-regulation of immune response to tumor cell|upregulation of immune response to tumor cell Any process that activates or increases the frequency, rate, or extent of an immune response to tumor cell. GO:0002834 regulation of response to tumor cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002834 regulation of response to tumour cell Any process that modulates the frequency, rate, or extent of a response to tumor cell. GO:0002835 negative regulation of response to tumor cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002835 negative regulation of response to tumour cell|down-regulation of response to tumor cell|downregulation of response to tumor cell|down regulation of response to tumor cell|inhibition of response to tumor cell Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to tumor cell. GO:0002836 positive regulation of response to tumor cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002836 positive regulation of response to tumour cell|stimulation of response to tumor cell|up-regulation of response to tumor cell|activation of response to tumor cell|up regulation of response to tumor cell|upregulation of response to tumor cell Any process that activates or increases the frequency, rate, or extent of a response to tumor cell. GO:0002837 regulation of immune response to tumor cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002837 regulation of immune response to tumour cell Any process that modulates the frequency, rate, or extent of an immune response to tumor cell. GO:0002800 regulation of antifungal peptide secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002800 Any process that modulates the frequency, rate, or extent of antifungal peptide secretion. GO:0002809 negative regulation of antibacterial peptide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002809 downregulation of antibacterial peptide biosynthetic process|down regulation of antibacterial peptide biosynthetic process|inhibition of antibacterial peptide biosynthetic process|down-regulation of antibacterial peptide biosynthetic process Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide biosynthesis. CHEBI:41963 (-)-taxifolin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_41963 GO:0002805 regulation of antimicrobial peptide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002805 Any process that modulates the frequency, rate, or extent of antimicrobial peptide biosynthesis. GO:0002806 negative regulation of antimicrobial peptide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002806 downregulation of antimicrobial peptide biosynthetic process|down regulation of antimicrobial peptide biosynthetic process|inhibition of antimicrobial peptide biosynthetic process|down-regulation of antimicrobial peptide biosynthetic process Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide biosynthesis. GO:0002807 positive regulation of antimicrobial peptide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002807 upregulation of antimicrobial peptide biosynthetic process|stimulation of antimicrobial peptide biosynthetic process|up-regulation of antimicrobial peptide biosynthetic process|activation of antimicrobial peptide biosynthetic process|up regulation of antimicrobial peptide biosynthetic process Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide biosynthesis. GO:0002808 regulation of antibacterial peptide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002808 Any process that modulates the frequency, rate, or extent of antibacterial peptide biosynthesis. GOP:systematic_synonym Systematic synonym biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/go#systematic_synonym GO:0002801 negative regulation of antifungal peptide secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002801 downregulation of antifungal peptide secretion|down regulation of antifungal peptide secretion|inhibition of antifungal peptide secretion|down-regulation of antifungal peptide secretion Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide secretion. GO:0002802 positive regulation of antifungal peptide secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002802 up regulation of antifungal peptide secretion|upregulation of antifungal peptide secretion|stimulation of antifungal peptide secretion|activation of antifungal peptide secretion|up-regulation of antifungal peptide secretion Any process that activates or increases the frequency, rate, or extent of antifungal peptide secretion. GO:0002803 positive regulation of antibacterial peptide production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002803 stimulation of antibacterial peptide production|up-regulation of antibacterial peptide production|activation of antibacterial peptide production|up regulation of antibacterial peptide production|upregulation of antibacterial peptide production Any process that activates or increases the frequency, rate, or extent of antibacterial peptide production. GO:0002804 positive regulation of antifungal peptide production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002804 up regulation of antifungal peptide production|activation of antifungal peptide production|stimulation of antifungal peptide production|up-regulation of antifungal peptide production|upregulation of antifungal peptide production Any process that activates or increases the frequency, rate, or extent of antifungal peptide production. CHEBI:26338 prostaglandins E biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_26338 GO:0002810 regulation of antifungal peptide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002810 Any process that modulates the frequency, rate, or extent of antifungal peptide biosynthesis. GO:0002811 negative regulation of antifungal peptide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002811 down-regulation of antifungal peptide biosynthetic process|inhibition of antifungal peptide biosynthetic process|down regulation of antifungal peptide biosynthetic process|downregulation of antifungal peptide biosynthetic process Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide biosynthesis. CHEBI:26334 prostaglandins A biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_26334 CHEBI:26335 prostaglandins B biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_26335 CHEBI:26336 prostaglandins C biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_26336 CHEBI:26337 prostaglandins D biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_26337 CHEBI:26333 prostaglandin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26333 CHEBI:9555 tioguanine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_9555 GO:0002816 regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002816 Any process that modulates the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria. GO:0002817 negative regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002817 down-regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria|downregulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria|down regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria|inhibition of biosynthetic process of antibacterial peptides active against Gram-positive bacteria Any process that stops, prevents, or reduces the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria. GO:0002818 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0002818 GO:0002819 regulation of adaptive immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002819 Any process that modulates the frequency, rate, or extent of an adaptive immune response. GO:0002812 biosynthetic process of antibacterial peptides active against Gram-negative bacteria biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002812 The chemical reactions and pathways resulting in the formation of an antibacterial peptide with activity against Gram-negative bacteria. GO:0002813 regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002813 Any process that modulates the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria. CHEBI:9553 thioglucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_9553 GO:0002814 negative regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002814 down-regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria|downregulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria|down regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria|inhibition of biosynthetic process of antibacterial peptides active against Gram-negative bacteria Any process that stops, prevents, or reduces the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria. GO:0002815 biosynthetic process of antibacterial peptides active against Gram-positive bacteria biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002815 The chemical reactions and pathways resulting in the formation of an antibacterial peptide with activity against Gram-positive bacteria. GO:0075720 establishment of episomal latency biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075720 establishment of plasmid latency|establishment as a plasmid prophage A process by which a virus establishes a latent state within its host as an episome, where the viral genome remains silent in the cytoplasm or nucleus as a distinct genetic entity. GO:0051753 mannan synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051753 mannan beta-1,4-mannosyltransferase activity|galactomannan beta-1,4-mannosyltransferase activity Catalysis of the reaction: mannan(n) + GDP-mannose = mannan(n+1) + GDP. This reaction is the formation of the beta-(1->4)-linked mannan backbone in substrates such as galactomannan. GO:0051754 meiotic sister chromatid cohesion, centromeric biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051754 centromeric meiotic sister chromatin cohesion|sister chromatid cohesion at centromere at meiosis I|meiotic sister chromatid cohesion at centromere The cell cycle process in which centromeres of sister chromatids are joined during meiosis. GO:0051751 alpha-1,4-mannosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051751 Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->4) linkage. GO:0051752 phosphoglucan, water dikinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051752 MetaCyc:2.7.9.5-RXN|EC:2.7.9.5 ATP:phospho-alpha-glucan, water phosphotransferase activity|PWD|OK1 Catalysis of the reaction: ATP + [phospho-alpha-glucan] + H2O = AMP + O-phospho-[phospho-alpha-glucan] + phosphate. GO:0051757 meiotic sister chromatid separation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051757 meiotic sister chromatid resolution The process in which sister chromatids are physically detached from each other during meiosis. GO:0051758 homologous chromosome movement towards spindle pole in meiosis I anaphase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051758 meiosis I, homologous chromosome movement towards spindle pole|homologous chromosome movement towards spindle pole during meiosis I The directed movement of homologous chromosomes from the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during meiosis I anaphase. GO:0051755 meiotic sister chromatid arm separation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051755 The cell cycle process in which sister chromatid arms are physically detached from each other during meiosis. GO:0051756 meiotic sister chromatid centromere separation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051756 The cell cycle process in which the centromeres of sister chromatids are physically detached from each other during meiosis. GO:0051759 sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051759 sister chromosome movement towards spindle pole during meiosis II|meiosis II, sister chromosome movement towards spindle pole The directed movement of sister chromosomes from the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during meiosis II. GO:0036112 medium-chain fatty-acyl-CoA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036112 medium-chain fatty acyl-CoA metabolism|medium-chain fatty acyl CoA metabolic process The chemical reactions and pathways involving medium-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. A medium-chain fatty acid is a fatty acid with a chain length of between C6 and C12. GO:0036113 very long-chain fatty-acyl-CoA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036113 very long-chain fatty-acyl-CoA catabolism|very long-chain fatty-acyl-CoA degradation|very long-chain fatty-acyl-CoA breakdown The chemical reactions and pathways resulting in the breakdown of very long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22. GO:0036114 medium-chain fatty-acyl-CoA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036114 medium-chain fatty-acyl-CoA breakdown|medium-chain fatty-acyl-CoA catabolism|medium-chain fatty-acyl-CoA degradation The chemical reactions and pathways resulting in the breakdown of medium-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A medium-chain fatty acid is a fatty acid with a chain length of between C6 and C12. GO:0036115 fatty-acyl-CoA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036115 fatty-acyl-CoA catabolism|fatty-acyl-CoA degradation|fatty-acyl-CoA breakdown The chemical reactions and pathways resulting in the breakdown of a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group. GO:0036116 long-chain fatty-acyl-CoA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036116 long-chain fatty-acyl-CoA degradation|long-chain fatty-acyl-CoA breakdown|long-chain fatty-acyl-CoA catabolism The chemical reactions and pathways resulting in the breakdown of long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22. GO:0036117 hyaluranon cable biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036117 HA cable A cable structure, surrounding some cell types (e.g. proximal or bronchial tubular epithelial cells), and composed of hyaluranon (HA), a ubiquitous connective tissue glycosaminoglycan. GO:0036118 hyaluranon cable assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036118 HA cable assembly A process that results in the aggregation, arrangement and bonding together of a hyaluranon cable, a cable structure, surrounding some cell types (e.g. proximal or bronchial tubular epithelial cells), and composed of hyaluranon (HA), a ubiquitous connective tissue glycosaminoglycan. GO:0036119 response to platelet-derived growth factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036119 response to PDGF stimulus|response to platelet-derived growth factor stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus. CHEBI:75279 1-acyl-2-hexadecanoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75279 GO:0051750 delta3,5-delta2,4-dienoyl-CoA isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051750 delta(3,5),delta(2,4)-dienoyl-coenzyme A isomerase activity|delta5-delta2,4-dienoyl-CoA isomerase activity Catalysis of the isomerization of 3,5-dienoyl-CoA to 2,4-dienoyl-CoA. GO:0036110 cellular response to inositol starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036110 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of inositol. GO:0036111 very long-chain fatty-acyl-CoA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036111 very long-chain fatty acyl CoA metabolic process|very long-chain fatty acyl-CoA metabolism The chemical reactions and pathways involving very long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22. GO:0051764 actin crosslink formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051764 formation of actin crosslink|actin crosslinking|actin bundling|bridging actin filaments The process in which two or more actin filaments are connected together by proteins that act as crosslinks between the filaments. The crosslinked filaments may be on the same or differing axes. GO:0051765 inositol tetrakisphosphate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051765 Catalysis of the reaction: inositol tetrakisphosphate + ATP = inositol pentakisphosphate + ADP. GO:0075710 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075710 GO:0051762 sesquiterpene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051762 The chemical reactions and pathways resulting in the formation of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene. GO:0051763 sesquiterpene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051763 The chemical reactions and pathways resulting in the breakdown of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene. CHEBI:145434 oleoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_145434 GO:0075713 establishment of integrated proviral latency biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075713 VZ:980 prophage integration|provirus integration A process by which the virus integrates into the host genome and establishes as a stable provirus or prophage. GO:0051768 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051768 GO:0051769 regulation of nitric-oxide synthase biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051769 regulation of nitric-oxide synthase (type 2) biosynthetic process|regulation of nitric-oxide synthase (type 2) biosynthesis|regulation of NOS biosynthetic process|regulation of NOS2 synthase biosynthetic process|regulation of NOS2 synthase biosynthesis|regulation of NOS biosynthesis|regulation of nitric-oxide synthase (type II) biosynthetic process|regulation of nitric-oxide synthase (type II) biosynthesis|regulation of NO synthase biosynthetic process|regulation of NO synthase biosynthesis|regulation of nitric-oxide synthase 2 biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric-oxide synthase enzyme. CHEBI:145437 uncoupling protein inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145437 GO:0051766 inositol trisphosphate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051766 Catalysis of the reaction: inositol trisphosphate + ATP = inositol tetrakisphosphate + ADP. GO:0051767 nitric-oxide synthase biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051767 NOS2 synthase biosynthesis|NOS2 synthase biosynthetic process|brain nitric-oxide synthase biosynthetic process|NOS biosynthesis|NOS biosynthetic process|NO synthase biosynthesis|NO synthase biosynthetic process|nitric-oxide synthase (type II) biosynthesis|nitric-oxide synthase (type II) biosynthetic process|inducible nitric-oxide synthase biosynthetic process|nitric-oxide synthase 2 biosynthetic process|nitric-oxide synthase (type 2) biosynthetic process|nitric-oxide synthase-1 biosynthetic process|nitric-oxide synthase (type 2) biosynthesis|endothelial nitric-oxide synthase biosynthetic process|nitric-oxide synthase-2 biosynthetic process|nitric-oxide synthase-3 biosynthetic process|NOS1 biosynthesis|NOS2 biosynthesis|NOS3 biosynthesis The chemical reactions and pathways resulting in the formation of a nitric-oxide synthase, an enzyme which catalyzes the reaction L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+. GO:0075716 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075716 GO:0036109 alpha-linolenic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036109 Wikipedia:Linoleic_acid alpha-linolenic acid metabolism|ALA metabolism The chemical reactions and pathways involving alpha-linolenic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2. GO:0075717 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075717 GO:0036101 leukotriene B4 catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036101 leukotriene B4 catabolism|leukotriene B4 degradation|LTB4 catabolism|leukotriene B4 breakdown The chemical reactions and pathways resulting in the breakdown of leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents. GO:0036102 leukotriene B4 metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036102 LTB4 metabolism The chemical reactions and pathways involving leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents. GO:0036103 Kdo2-lipid A metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036103 Kdo2-lipid A metabolism The chemical reactions and pathways involving Kdo2-lipid A, a lipopolysaccharide (LPS) component. GO:0036104 Kdo2-lipid A biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036104 Kdo2-lipid A anabolism|Kdo2-lipid A synthesis|Kdo2-lipid A formation|Kdo2-lipid A biosynthesis|di[3-deoxy-D-manno-octulosonyl]-lipid A biosynthesis|KDO(2)-lipid A biosynthesis The chemical reactions and pathways resulting in the formation of Kdo2-lipid A, a lipopolysaccharide (LPS) component. GO:0036105 peroxisome membrane class-1 targeting sequence binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036105 PEX19-dependent mPTS binding|class 1 mPTS binding Interacting selectively and non-covalently with a class I peroxisomal membrane targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome membrane in a PEX19-dependent manner. CHEBI:75282 ergosterol biosynthesis inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75282 GO:0036106 peroxisome membrane class-2 targeting sequence binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036106 PEX19-independent mPTS binding|class 2 mPTS binding Interacting selectively and non-covalently with a class II peroxisomal membrane targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome membrane in a PEX19-independent manner. CHEBI:75280 1-acyl-2-palmitoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75280 GO:0036107 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036107 4-amino-4-deoxy-alpha-L-arabinose undecaprenyl phosphate metabolic process|undecaprenyl phosphate alpha-L-Ara4N metabolism The chemical reactions and pathways involving 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate, a precursor of 4-amino-4-deoxy-L-arabinose (L-Ara4N). GO:0036108 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036108 undecaprenyl phosphate alpha-L-Ara4N biosynthesis|4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate anabolism|4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate synthesis|4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate formation|4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthesis The chemical reactions and pathways resulting in the formation of 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate, a precursor of 4-amino-4-deoxy-L-arabinose (L-Ara4N). CHEBI:75287 (S)-dichlorprop(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75287 CHEBI:75284 (R)-2-(4-chloro-2-methylphenoxy)propanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75284 CHEBI:75285 (S)-2-(4-chloro-2-methylphenoxy)propanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75285 GO:0051760 meiotic sister chromatid cohesion, arms biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051760 meiotic sister chromatid cohesion along arms|sister chromatid cohesion along arms at meiosis I The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the chromosome arms during meiosis. GO:0099703 induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099703 The induction of synaptic vesicle release by any process that leads to a rise in intracellular calcium ion concentration at the presynapse. This is the first step in synaptic transmission. GO:0051761 sesquiterpene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051761 sesquiterpene metabolism The chemical reactions and pathways involving sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene. CHEBI:75288 (R)-dichlorprop(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75288 GO:0036100 leukotriene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036100 leukotriene breakdown|leukotriene catabolism|leukotriene degradation The chemical reactions and pathways resulting in the breakdown of a leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid. CHEBI:75289 1-O-(alk-1-enyl)-2-palmitoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75289 GO:0051775 response to redox state biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051775 redox signal response Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating redox state. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important. GO:0051776 detection of redox state biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051776 redox sensing The series of events in which a chemical stimulus indicating redox state is received and converted into a molecular signal. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important. CHEBI:9592 tiglic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_9592 GO:0051773 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051773 GO:0051774 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051774 GO:0051779 gibberellin 12-aldehyde oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051779 RHEA:22700|MetaCyc:RXN1F-161 GA12-aldehyde oxidase activity Catalysis of the reaction: gibberellin 12-aldehyde + NADPH + H+ + O2 = gibberellin 12 + NADP+ + H2O. This is the third of three successive reactions resulting in the oxidation of ent-kaurenoate (ent-kaurenoic acid) to gibberellin 12 (GA12). GO:0051777 ent-kaurenoate oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051777 RHEA:19241|MetaCyc:1.14.13.79-RXN ent-kaur-16-en-19-oate,NADPH:oxygen oxidoreductase (hydroxylating) activity|ent-kaurenoic acid oxidase activity Catalysis of the reaction: ent-kaurenoate + NADPH + O2 = ent-7-alpha-hydroxykaurenoate + NADP+ + H2O. This is the first of three successive reactions resulting in the oxidation of ent-kaurenoate (ent-kaurenoic acid) to gibberellin 12 (GA12). GO:0051778 ent-7-alpha-hydroxykaurenoate oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051778 MetaCyc:RXN1F-160|RHEA:22904 Catalysis of the reaction: ent-7-alpha-hydroxykaurenoate + NADPH + H+ + O2 = gibberellin 12-aldehyde + NADP+ + 2 H2O. This is the second of three successive reactions resulting in the oxidation of ent-kaurenoate (ent-kaurenoic acid) to gibberellin 12 (GA12). GO:0061100 lung neuroendocrine cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061100 The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the lung epithelium. GO:0061101 neuroendocrine cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061101 The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A neuroendocrine cell is a cell that receives input form a neuron which controls the secretion of an endocrine substance. GO:0061102 stomach neuroendocrine cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061102 gastric neuroendocrine cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the stomach epithelium. CHEBI:75290 1-O-octadecyl-2-palmitoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75290 GO:0061103 carotid body glomus cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061103 The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a glomus cell of the carotid body. The carotid body is a specialized chemosensory organ that helps respond to hypoxia. GO:0061104 adrenal chromaffin cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061104 The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an adrenal chromaffin cell. An adrenal chromaffin cell is a neuroendocrine cell that stores epinephrine secretory vesicles. GO:0061105 regulation of stomach neuroendocrine cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061105 Any process that modulates the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach. GO:0061106 negative regulation of stomach neuroendocrine cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061106 Any process that decreases the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach. CHEBI:75294 1-icosanoyl-2-palmitoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75294 CHEBI:75291 epsilon-rhodomycinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75291 GO:0061107 seminal vesicle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061107 The progression of the seminal vesicle over time, from its formation to the mature structure. The seminal vesicle is a gland that contributes to the production of semen. GO:0061108 seminal vesicle epithelium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061108 The progression of the seminal vesicle epithelium over time, from its formation to the mature structure. CHEBI:51286 tetracenequinones biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51286 CHEBI:9588 ticlopidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_9588 GO:0061109 dense core granule organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061109 dense core granule organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dense core granule. A dense core granule is a secretory organelle found in endocrine cells. CHEBI:75297 13-deoxydaunorubicin(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75297 CHEBI:75296 13-dihydrodaunorubicin(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75296 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051771 downregulation of nitric-oxide synthase 2 biosynthetic process|down regulation of nitric-oxide synthase 2 biosynthetic process|inhibition of nitric-oxide synthase 2 biosynthetic process|down-regulation of nitric-oxide synthase biosynthetic process|negative regulation of NOS2 synthase biosynthesis|negative regulation of NOS2 synthase biosynthetic process|negative regulation of NOS biosynthesis|negative regulation of NOS biosynthetic process|negative regulation of nitric-oxide synthase (type II) biosynthesis|negative regulation of nitric-oxide synthase (type II) biosynthetic process|negative regulation of NO synthase biosynthetic process|negative regulation of NO synthase biosynthesis|downregulation of nitric-oxide synthase biosynthetic process|negative regulation of nitric-oxide synthase (type 2) biosynthetic process|negative regulation of nitric-oxide synthase (type 2) biosynthesis|down-regulation of nitric-oxide synthase 2 biosynthetic process|negative regulation of nitric-oxide synthase 2 biosynthetic process|down regulation of nitric-oxide synthase biosynthetic process|inhibition of nitric-oxide synthase biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric-oxide synthase enzyme. CHEBI:51282 2-amino-2,3,7-trideoxy-D-lyxo-hept-6-ulosonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51282 GO:0051772 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051772 CHEBI:51283 hydroxypyruvaldehyde phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51283 CHEBI:51284 1-deoxy-D-threo-hexo-2,5-diulose 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51284 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051770 stimulation of nitric-oxide synthase biosynthetic process|up-regulation of nitric-oxide synthase biosynthetic process|activation of nitric-oxide synthase biosynthetic process|upregulation of nitric-oxide synthase 2 biosynthetic process|positive regulation of NOS2 synthase biosynthetic process|positive regulation of NOS biosynthesis|positive regulation of NOS2 synthase biosynthesis|up regulation of nitric-oxide synthase biosynthetic process|positive regulation of NOS biosynthetic process|up-regulation of nitric-oxide synthase 2 biosynthetic process|positive regulation of nitric-oxide synthase (type 2) biosynthesis|positive regulation of nitric-oxide synthase (type 2) biosynthetic process|stimulation of nitric-oxide synthase 2 biosynthetic process|positive regulation of NO synthase biosynthetic process|positive regulation of nitric-oxide synthase (type II) biosynthesis|positive regulation of NO synthase biosynthesis|positive regulation of nitric-oxide synthase (type II) biosynthetic process|activation of nitric-oxide synthase 2 biosynthetic process|upregulation of nitric-oxide synthase biosynthetic process|positive regulation of nitric-oxide synthase 2 biosynthetic process|up regulation of nitric-oxide synthase 2 biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric oxide synthase enzyme. CHEBI:51285 acenoquinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51285 GO:0051786 all-trans-retinol 13,14-reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051786 KEGG_REACTION:R07163|MetaCyc:1.3.99.23-RXN|Reactome:R-HSA-8956427|EC:1.3.99.23|RHEA:19193 retinol saturase activity|all-trans-retinol:all-trans-13,14-dihydroretinol saturase activity|(13,14)-all-trans-retinol saturase activity|RetSat activity|all-trans-13,14-dihydroretinol:acceptor 13,14-oxidoreductase activity Catalysis of the reaction: all-trans-13,14-dihydroretinol + A = all-trans-retinol + AH(2). Note that this reaction has only been observed to occur in the opposite direction. GO:0051787 misfolded protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051787 Reactome:R-HSA-5324632 Interacting selectively and non-covalently with a misfolded protein. GO:0075732 viral penetration into host nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075732 VZ:989 viral entry into host nucleus|viral import into host nucleus The crossing by the virus of the host nuclear membrane, either as naked viral genome or for small viruses as an intact capsid. GO:0051784 negative regulation of nuclear division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051784 inhibition of nuclear division|down-regulation of nuclear division|downregulation of nuclear division|down regulation of nuclear division Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information. GO:0075733 intracellular transport of virus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075733 viral genome transport in host cell|egress of virus within host cell|viral egress|intracellular virion transport|movement of virus within host cell|intracellular transport of viral material The directed movement of a virus, or part of a virus, within the host cell. GO:0051785 positive regulation of nuclear division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051785 upregulation of nuclear division|stimulation of nuclear division|up-regulation of nuclear division|activation of nuclear division|up regulation of nuclear division Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information. GO:0051788 response to misfolded protein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051788 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a misfolded protein stimulus. UBERON:4300230 forelimb wing bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_4300230 A wing bud that develops into a wing GO:0051789 obsolete response to protein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051789 response to protein stimulus|response to protein OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein stimulus. UBERON:4300231 forelimb wing bud mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_4300231 Mesenchyme that is part of a forelimb wing bud. CHEBI:51270 tetracenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51270 UBERON:4300229 pelvic fin bud mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_4300229 Mesechyme that is part of a pelvic fin bud. CHEBI:51276 thioureas biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51276 CHEBI:51277 thioester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_51277 GO:0051782 negative regulation of cell division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051782 down-regulation of cell division|inhibition of cell division|down regulation of cell division|downregulation of cell division Any process that stops, prevents, or reduces the frequency, rate or extent of cell division. GO:0051783 regulation of nuclear division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051783 Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information. UBERON:4300226 forelimb bud mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_4300226 Mesenchyme that is part of a forelimb bud. GO:0051780 behavioral response to nutrient biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051780 behavioural response to nutrient Any process that results in a change in the behavior of an organism as a result of a nutrient stimulus. UBERON:4300227 hindlimb bud mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_4300227 Mesenchyme that is part of a hindlimb bud. GO:0051781 positive regulation of cell division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051781 up regulation of cell division|activation of cell division|stimulation of cell division|up-regulation of cell division|upregulation of cell division Any process that activates or increases the frequency, rate or extent of cell division. UBERON:4300228 pectoral fin bud mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_4300228 Mesechyme that is part of a pectoral fin bud. GO:0051797 regulation of hair follicle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051797 Any process that modulates the frequency, rate or extent of hair follicle development. GO:0002786 regulation of antibacterial peptide production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002786 Any process that modulates the frequency, rate, or extent of antibacterial peptide production. GO:0051798 positive regulation of hair follicle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051798 up regulation of hair follicle development|activation of hair follicle development|stimulation of hair follicle development|up-regulation of hair follicle development|upregulation of hair follicle development Any process that activates or increases the frequency, rate or extent of hair follicle development. GO:0002787 negative regulation of antibacterial peptide production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002787 down-regulation of antibacterial peptide production|downregulation of antibacterial peptide production|down regulation of antibacterial peptide production|inhibition of antibacterial peptide production Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide production. GO:0051795 positive regulation of timing of catagen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051795 up-regulation of catagen|upregulation of catagen|activation of catagen|stimulation of catagen|up regulation of catagen|positive regulation of catagen Any process that activates or increases the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle. GO:0002788 regulation of antifungal peptide production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002788 Any process that modulates the frequency, rate, or extent of antifungal peptide production. GO:0051796 negative regulation of timing of catagen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051796 down-regulation of catagen|negative regulation of catagen|inhibition of catagen|down regulation of catagen|downregulation of catagen Any process that stops, prevents, or reduces the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle. GO:0002789 negative regulation of antifungal peptide production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002789 down-regulation of antifungal peptide production|inhibition of antifungal peptide production|down regulation of antifungal peptide production|downregulation of antifungal peptide production Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide production. GO:0002782 antifungal peptide secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002782 The regulated release of an antifungal peptide from a cell or a tissue. GO:0002783 antifungal peptide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002783 The chemical reactions and pathways resulting in the formation of an antifungal peptide. CHEBI:51269 acenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51269 GO:0051799 negative regulation of hair follicle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051799 down regulation of hair follicle development|downregulation of hair follicle development|down-regulation of hair follicle development|inhibition of hair follicle development Any process that stops, prevents, or reduces the frequency, rate or extent of hair follicle development. GO:0002784 regulation of antimicrobial peptide production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002784 Any process that modulates the frequency, rate, or extent of antimicrobial peptide production. GO:0002785 negative regulation of antimicrobial peptide production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002785 down-regulation of antimicrobial peptide production|downregulation of antimicrobial peptide production|down regulation of antimicrobial peptide production|inhibition of antimicrobial peptide production Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide production. GO:0002780 antibacterial peptide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002780 The chemical reactions and pathways resulting in the formation of an antibacterial peptide. GO:0002781 antifungal peptide production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0002781 The synthesis or release of an antifungal peptide during an immune response, resulting in an increase in intracellular or extracellular levels. GO:0061120 regulation of positive chemotaxis to cAMP by DIF-1 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061120 Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone. GO:0061121 regulation of positive chemotaxis to cAMP by DIF-2 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061121 Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone. GO:0061122 positive regulation of positive chemotaxis to cAMP biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061122 Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP. GO:0061123 negative regulation of positive chemotaxis to cAMP biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061123 Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP. GO:0061124 positive regulation of positive chemotaxis to cAMP by chlorinated alkylphenone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061124 Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions. GO:0061125 negative regulation of positive chemotaxis to cAMP by chlorinated alkylphenone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061125 Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions. GO:0061126 positive regulation of positive chemotaxis to cAMP by DIF-1 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061126 Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone. GO:0061127 negative regulation of positive chemotaxis to cAMP by DIF-1 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061127 Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone. GO:0061128 positive regulation of chemotaxis to cAMP by DIF-2 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061128 Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone. GO:0061129 negative regulation of positive chemotaxis to cAMP by DIF-2 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061129 Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone. GO:0051790 short-chain fatty acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051790 short-chain fatty acid synthesis|short-chain fatty acid formation|short-chain fatty acid biosynthesis|short chain fatty acid biosynthesis|short chain fatty acid biosynthetic process|short-chain fatty acid anabolism The chemical reactions and pathways resulting in the formation of fatty acids with a chain length of less than C6. GO:0099738 cell cortex region biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0099738 perimembrane region The complete extent of cell cortex that underlies some some region of the plasma membrane. GO:0051793 medium-chain fatty acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051793 medium-chain fatty acid degradation|medium-chain fatty acid catabolism|medium-chain fatty acid breakdown|medium chain fatty acid catabolism|medium chain fatty acid catabolic process The chemical reactions and pathways resulting in the breakdown of any fatty acid with a chain length of between C6 and C12. GO:0051794 regulation of timing of catagen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051794 regulation of catagen Any process that modulates the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle. GO:0051791 medium-chain fatty acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051791 medium chain fatty acid metabolism|medium-chain fatty acid metabolism|medium chain fatty acid metabolic process The chemical reactions and pathways involving medium-chain fatty acids, any fatty acid with a chain length of between C6 and C12. GO:0051792 medium-chain fatty acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051792 medium chain fatty acid biosynthetic process|medium chain fatty acid biosynthesis|medium-chain fatty acid biosynthesis|medium-chain fatty acid anabolism|medium-chain fatty acid synthesis|medium-chain fatty acid formation The chemical reactions and pathways resulting in the formation of any fatty acid with a chain length of between C6 and C12. GO:0002797 regulation of antibacterial peptide secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002797 Any process that modulates the frequency, rate, or extent of antibacterial peptide secretion. GO:0002798 negative regulation of antibacterial peptide secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002798 down-regulation of antibacterial peptide secretion|inhibition of antibacterial peptide secretion|down regulation of antibacterial peptide secretion|downregulation of antibacterial peptide secretion Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide secretion. GO:0002799 positive regulation of antibacterial peptide secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002799 up regulation of antibacterial peptide secretion|activation of antibacterial peptide secretion|stimulation of antibacterial peptide secretion|up-regulation of antibacterial peptide secretion|upregulation of antibacterial peptide secretion Any process that activates or increases the frequency, rate, or extent of antibacterial peptide secretion. GO:0002793 positive regulation of peptide secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002793 up-regulation of peptide secretion|upregulation of peptide secretion|up regulation of peptide secretion|activation of peptide secretion|stimulation of peptide secretion Any process that activates or increases the frequency, rate, or extent of peptide secretion. GO:0002794 regulation of antimicrobial peptide secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002794 Any process that modulates the frequency, rate, or extent of antimicrobial peptide secretion. GO:0002795 negative regulation of antimicrobial peptide secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002795 down-regulation of antimicrobial peptide secretion|inhibition of antimicrobial peptide secretion|down regulation of antimicrobial peptide secretion|downregulation of antimicrobial peptide secretion Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide secretion. GO:0002796 positive regulation of antimicrobial peptide secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002796 up regulation of antimicrobial peptide secretion|activation of antimicrobial peptide secretion|stimulation of antimicrobial peptide secretion|up-regulation of antimicrobial peptide secretion|upregulation of antimicrobial peptide secretion Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide secretion. GO:0002790 peptide secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002790 The controlled release of a peptide from a cell or a tissue. GO:0002791 regulation of peptide secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002791 Any process that modulates the frequency, rate, or extent of peptide secretion. GO:0002792 negative regulation of peptide secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002792 down regulation of peptide secretion|downregulation of peptide secretion|down-regulation of peptide secretion|inhibition of peptide secretion Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion. GO:0061110 dense core granule biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061110 A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a dense core granule. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the dense core granule. GO:0061111 epithelial-mesenchymal cell signaling involved in lung development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061111 epithelial-mesenchymal cell signalling involved in lung development Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell and contributes to the progression of the lung over time from its initial formation to the mature organ. GO:0061112 negative regulation of bud outgrowth involved in lung branching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061112 Any process that decreases the rate, frequency, or extent of bud outgrowth involved in lung branching. GO:0061113 pancreas morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061113 Morphogenesis of the pancreas. Morphogenesis is the process in which anatomical structures are generated and organized. GO:0061114 branching involved in pancreas morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061114 The process in which the branches of the pancreas are generated and organized. GO:0061115 lung proximal/distal axis specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061115 The establishment, maintenance and elaboration of the proximal/distal axis of the lung. The proximal/distal axis of the lung is defined by a line that runs from the trachea to the alveoli. GO:0061116 ductus venosus closure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061116 The morphogenesis process in which the ductus venosus changes to no longer permit blood flow after birth. GO:0061117 negative regulation of heart growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061117 Any process that decreases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart. GO:0061118 regulation of positive chemotaxis to cAMP biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061118 Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP. GO:0061119 regulation of positive chemotaxis to cAMP by chlorinated alkylphenone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061119 Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions. GO:0002764 immune response-regulating signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002764 immune response-regulating signalling pathway The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to the activation, perpetuation, or inhibition of an immune response. GO:0002765 immune response-inhibiting signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002765 The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to inhibition of an immune response. GO:0002766 innate immune response-inhibiting signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002766 The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to inhibition of an innate immune response. GO:0002767 immune response-inhibiting cell surface receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002767 immune response-inhibiting cell surface receptor signalling pathway A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell capable of inhibiting an immune response. GO:0002760 positive regulation of antimicrobial humoral response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002760 up regulation of antimicrobial humoral response|upregulation of antimicrobial humoral response|stimulation of antimicrobial humoral response|up-regulation of antimicrobial humoral response|activation of antimicrobial humoral response Any process that activates or increases the frequency, rate, or extent of an antimicrobial humoral response. GO:0002761 regulation of myeloid leukocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002761 Any process that modulates the frequency, rate, or extent of myeloid leukocyte differentiation. GO:0002762 negative regulation of myeloid leukocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002762 down regulation of myeloid leukocyte differentiation|downregulation of myeloid leukocyte differentiation|down-regulation of myeloid leukocyte differentiation|inhibition of myeloid leukocyte differentiation Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation. GO:0002763 positive regulation of myeloid leukocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002763 upregulation of myeloid leukocyte differentiation|up regulation of myeloid leukocyte differentiation|activation of myeloid leukocyte differentiation|stimulation of myeloid leukocyte differentiation|up-regulation of myeloid leukocyte differentiation Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation. CHEBI:26287 propane-1,3-diols biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26287 CHEBI:26288 propanediol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26288 GO:0061140 lung secretory cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061140 The process in which a relatively unspecialized cell acquires specialized features of a lung secretory cell. A lung secretory cell is a specialized epithelial cell of the lung that contains large secretory granules in its apical part. CHEBI:26282 propanals biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26282 GO:0061141 lung ciliated cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061141 The process in which a relatively unspecialized cell acquires specialized features of a lung ciliated cell. A lung ciliated cell is a specialized lung epithelial cell that contains cilia for moving substances released from lung secretory cells. GO:0061142 mesothelial-mesenchymal cell signaling involved in early lung development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061142 mesothelial-mesenchymal cell signalling involved in early lung development Any process that mediates the transfer of information from a mesothelial cell to an epithelial cell and contributes to the development of the lung. GO:0061143 alveolar primary septum development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061143 The progression of a primary alveolar septum over time, from its formation to the mature structure. A primary alveolar septum is a specialized epithelium that surrounds the saccule as it forms. CHEBI:26284 propane-1,2-diols biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26284 GO:0061144 alveolar secondary septum development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061144 The progression of a secondary alveolar septum over time, from its formation to the mature structure. A secondary alveolar septum is a specialized epithelium that subdivides the initial saccule. GO:0061145 lung smooth muscle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061145 The process whose specific outcome is the progression of smooth muscle in the lung over time, from its formation to the mature structure. GO:0061146 Peyer's patch morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061146 The process in which a Peyer's patch is generated and organized. Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes. GO:0061147 endocardial endothelium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061147 The progression of the endocardial endothelium over time, from its initial formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. GO:0061148 extracellular matrix organization involved in endocardium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061148 extracellular matrix organisation involved in endocardium development A process which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix of the endocardium. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. CHEBI:26292 propanones biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26292 GO:0061149 BMP signaling pathway involved in ureter morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061149 BMP signalling pathway involved in ureter morphogenesis A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the shaping of the ureter. The ureter is a tube that extends from the kidney to the bladder. GO:0002768 immune response-regulating cell surface receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002768 immune response-regulating cell surface receptor signalling pathway A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell capable of activating, perpetuating, or inhibiting an immune response. GO:0002769 natural killer cell inhibitory signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002769 natural killer cell inhibitory signalling pathway|killer cell inhibitory receptor signaling pathway|NK cell inhibitory signaling pathway|inhibitory KIR signaling pathway|Ly49 inhibitory receptor signaling pathway A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a natural killer cell capable of inhibiting an immune effector process contributing to an immune response. GO:0002775 antimicrobial peptide production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0002775 The synthesis or release of an antimicrobial peptide during an immune response, resulting in an increase in intracellular or extracellular levels. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa. GO:0002776 antimicrobial peptide secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002776 The regulated release of an antimicrobial peptide from a cell or a tissue. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa. GO:0002777 antimicrobial peptide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002777 The chemical reactions and pathways resulting in the formation of an antimicrobial peptide. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa. GO:0002778 antibacterial peptide production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0002778 The synthesis or release of an antibacterial peptide during an immune response, resulting in an increase in intracellular or extracellular levels. GO:0002771 inhibitory killer cell immunoglobulin-like receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002771 KIR signaling pathway|inhibitory killer cell immunoglobulin-like receptor signalling pathway|killer cell inhibitory receptor signaling pathway A series of molecular signals initiated by the binding of an extracellular ligand to a inhibitory killer cell immunoglobulin-like receptor capable of inhibiting an immune effector process contributing to an immune response. GO:0002772 inhibitory C-type lectin receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002772 inhibitory C-type lectin receptor signalling pathway|Ly49 inhibitory receptor signaling pathway A series of molecular signals initiated by the binding of an extracellular ligand to an inhibitory C-type lectin receptor capable of inhibiting an immune effector process contributing to an immune response. GO:0002773 B cell inhibitory signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002773 B-cell inhibitory signaling pathway|B cell inhibitory signalling pathway|B lymphocyte inhibitory signaling pathwayBT-lymphocyte inhibitory signaling pathway A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a B cell capable of inhibiting an immune effector process contributing to an immune response. GO:0002774 Fc receptor mediated inhibitory signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002774 Fc receptor mediated inhibitory signalling pathway|Fc-receptor mediated inhibitory signaling pathway A series of molecular signals generated as a consequence of the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of inhibiting an immune effector process contributing to an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region. GO:0002770 T cell inhibitory signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002770 T cell inhibitory signalling pathway|T-lymphocyte inhibitory signaling pathway|T-cell inhibitory signaling pathway|T lymphocyte inhibitory signaling pathway A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a T cell capable of inhibiting an immune effector process contributing to an immune response. GO:0061130 pancreatic bud formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061130 The morphogenetic process in which the foregut region specified to become the pancreas forms a bud. GO:0061131 pancreas field specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061131 The process in which a specific region of the gut is delineated into the area in which the pancreas will develop. GO:0061132 pancreas induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061132 The close range interaction of two or more cells or tissues that causes the cells of the gut to change their fates and specify the development of the pancreas. GO:0061133 endopeptidase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061133 Increases the activity of an endopeptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides. CHEBI:26296 propanoyl-CoAs biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26296 GO:0061134 peptidase regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061134 Modulates the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds. GO:0061135 endopeptidase regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061135 Modulates the activity of a peptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides. GO:0061136 regulation of proteasomal protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061136 Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome. GO:0061137 bud dilation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061137 The process in which a branch bud increases radially. A branch bud is the initial area of outgrowth in the formation of a new branch. GO:0061138 morphogenesis of a branching epithelium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061138 The process in which the anatomical structures of a branched epithelium are generated and organized. GO:0061139 bud field specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061139 The regionalization process in which the identity of a bud primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized. GO:0002779 antibacterial peptide secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002779 The regulated release of an antibacterial peptide from a cell or a tissue. CHEBI:90837 3-O-(N-acetyl-beta-D-glucosaminyl)-L-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90837 CHEBI:90838 O-(N-acetyl-beta-D-glucosaminyl)-L-serine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90838 CHEBI:90839 3-O-(N-acetyl-beta-D-glucosaminyl)-L-threonine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90839 CHEBI:90832 NMNH(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90832 CHEBI:90833 5-hydroperoxy-15-HETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90833 GO:0036192 3-hydroxyindolin-2-one monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036192 EC:1.14.14.109|RHEA:31927|KEGG_REACTION:R07422 3-hydroxyindolin-2-one,NAD(P)H:oxygen oxidoreductase (2-hydroxy-2H-1,4-benzoxazin-3(4H)-one-forming) Catalysis of the reaction: 3-hydroxyindolin-2-one + NAD(P)H + H+ + O2 = 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + NAD(P)+ + H2O. GO:0036193 2-hydroxy-1,4-benzoxazin-3-one monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036193 RHEA:31939|EC:1.14.14.110|KEGG_REACTION:R07423 Catalysis of the reaction: 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + NAD(P)H + H+ + O2 = 2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one + NAD(P)+ + H2O. GO:0036194 muscle cell projection biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036194 myopodia|myocyte projection|muscle arm A prolongation or process extending from a muscle cell. A muscle cell is a mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns. GO:0036195 muscle cell projection membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036195 The portion of the plasma membrane surrounding a muscle cell projection. GO:0036196 zymosterol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036196 The chemical reactions and pathways involving zymosterol, (5alpha-cholesta-8,24-dien-3beta-ol). GO:0036197 zymosterol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036197 MetaCyc:PWY-6074|UniPathway:UPA00770 zymosterol anabolism|zymosterol synthesis|zymosterol biosynthesis|zymosterol formation The chemical reactions and pathways resulting in the formation of zymosterol, (5alpha-cholesta-8,24-dien-3beta-ol). GO:0036198 dTMP salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036198 UniPathway:UPA00578 deoxythymidine monophosphate biosynthesis via salvage pathway|dTMP biosynthesis via salvage pathway Any process which produces dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate) without de novo synthesis. GO:0036199 cholest-4-en-3-one 26-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036199 EC:1.14.15.29|RHEA:51564|KEGG_REACTION:R09859 Catalysis of the reaction: cholest-4-en-3-one + NADH + H+ + O2 = 26-hydroxycholest-4-en-3-one + NAD+ + H2O. This reaction involves the hydroxylation of the C26 carbon, followed by oxidation of the alcohol to the carboxylic acid via the aldehyde intermediate. CHEBI:75207 2-palmitoyl-2'-monolysocardiolipin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75207 CHEBI:75204 (S)-3,5-dihydroxyphenylglycine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75204 CHEBI:75205 2'-linoleoylcardiolipin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75205 CHEBI:75208 2-stearoyl-2'-monolysocardiolipin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75208 GO:0036190 indole-2-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036190 EC:1.14.14.153|RHEA:31899|KEGG_REACTION:R07403 Catalysis of the reaction: indole + NAD(P)H + H+ + O2 = indolin-2-one + NAD(P)+ + H2O. GO:0036191 indolin-2-one monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036191 RHEA:31919|EC:1.14.14.157|KEGG_REACTION:R07421 indolin-2-one,NAD(P)H:oxygen oxidoreductase (3-hydroxylating) Catalysis of the reaction: indolin-2-one + NAD(P)H + H+ + O2 = 3-hydroxyindolin-2-one + NAD(P)+ + H2O. CHEBI:75209 2-linoleoyl-2'-monolysocardiolipin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75209 GO:0120109 mitotic telomere clustering and tethering at nuclear periphery biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120109 The process in which the telomeres are gathered together to a small number of foci per chromosome (usually one per chromosome or fewer), and moved to and tethered at the nuclear periphery, as part of a mitotic cell cycle. GO:0120105 mitotic actomyosin contractile ring, intermediate layer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120105 actomyosin contractile ring, intermediate layer The region of the mitotic actomyosin ring in between the proximal layer and the actin filament layer. This region contains the accessory protein network, some actin filaments and connections between the proximal layer and the actin filament layer. CHEBI:90818 18(R)-HEPE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90818 GO:0120106 mitotic actomyosin contractile ring, distal actin filament layer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120106 actomyosin contractile ring, distal actin filament layer The region of the mitotic actomyosin ring containing actin filaments and cross linkers, myosin motors, and connections to the plasma membrane through the intermediate layer. It is further from the plasma membrane than the intermediate layer which it is adjacent to. CHEBI:90819 15(R)-HEPE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90819 GO:0120107 bacterial-type flagellum rotor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120107 The rotor complex of the bacterial-type flagellum consists of a membrane-anchored ring and the motor switch complex, which participates in the conversion of proton/Na+ energy into the mechanical work of rotation and controls the direction of flagellar rotation. GO:0120108 DNA-3'-diphospho-5'-guanosine diphosphatase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120108 EC:3.1.12.2|RHEA:52140 DNA-3'pp5'G guanylate hydrolase Catalysis of the reaction: (DNA)-3'-diphospho-5'-guanosine + H(2)O <=> (DNA)-3'-phosphate + GMP. GO:0036189 abieta-7,13-diene hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036189 RHEA:26217|KEGG_REACTION:R06351|MetaCyc:RXN-8507|EC:1.14.14.144 abietadiene hydroxylase Catalysis of the reaction: abieta-7,13-diene + NADPH + H+ + O2 = abieta-7,13-dien-18-ol + NADP+ + H2O. GO:0120101 bacterial-type flagellum stator complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120101 bacterial-type flagellum torque generator complex|bacterial-type flagellum motor force generator complex A hetero-hexameric complex of 2 membrane proteins, A and B, with stoichiometry A4B2. The A and B proteins form a channel through which flow the ions that power the bacterial-type flagellum. They form the stator, or nonrotating portion, of the flagellum motor with the B protein apparently attached to the peptidoglycan cell wall. Examples include the H+ driven MotA-MotB stator complex of Escherichia coli and Salmonella enterica, and the Na+ driven PomA-PomB stator complex of Vibrio and Shewanella species. CHEBI:90825 18-HEPE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90825 GO:0120102 bacterial-type flagellum secretion apparatus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120102 bacterial-type flagellum export apparatus A part of the bacterial-type flagellum that is located at the cytoplasmic side of the MS ring and composed of six membrane proteins (FlhA, FlhB, FliP, FliQ, FliR, and FliO, or orthologs thereof) and three soluble proteins (FliI, FliH, and FliJ, or orthologs thereof) in the cytoplasm. It is responsible for secretion of flagellar type III protein substrates, including the proteins of the flagellar rod, hook, and filament. CHEBI:90826 (5S)-hydroperoxy-18-hydroxy-EPE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90826 GO:0120103 centriolar subdistal appendage biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120103 subdistal appendage of mother centriole|subdistal appendage of centriole|subdistal appendage of basal body A protein complex which assembles on the mother centriole during cilium formation, adjacent and proximal to a centriolar distal appendage. In human, it contains ODF2, CNTRL, NIN, CCDC120c and CCDC68. GO:0120104 mitotic actomyosin contractile ring, proximal layer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120104 actomyosin contractile ring, proximal layer The region of the mitotic actomyosin ring adjacent to the plasma membrane where membrane bound scaffolds are located. CHEBI:90821 15-HPETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90821 CHEBI:90822 5-HPETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90822 CHEBI:90823 13-HPODE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90823 GO:0120100 bacterial-type flagellum motor biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120100 A transmembrane complex embedded in the cytoplasmic membrane which is the motor force, or torque, generator of the bacterial-type flagellum. The motor consists of a membrane-anchored rotor complex surrounded by one or more stator complexes in the cytoplasmic membrane. The stator consists of a hetero-hexameric complex of 2 membrane proteins, A and B, with stoichiometry A4B2. Examples are the H+ driven MotA-MotB stator complex of Escherichia coli and Salmonella enterica, and the Na+ driven PomA-PomB stator complex of Vibrio and Shewanella species. The rotor complex consists of a membrane-anchored ring and the motor switch complex, which controls the direction of flagellar rotation. CHEBI:90824 (7Z,10Z,13R,14E,16Z,19Z)-13-hydroxydocosapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90824 GO:0036181 protein localization to linear element biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036181 protein localisation to linear element A cellular protein localization process in which a protein is transported to, or maintained at, a linear element. A linear element is a proteinaceous scaffold associated with S. pombe chromosomes during meiotic prophase. GO:0036182 asperthecin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036182 asperthecin metabolism The chemical reactions and pathways involving asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans. GO:0036183 asperthecin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036183 asperthecin breakdown|asperthecin catabolism|asperthecin degradation The chemical reactions and pathways resulting in the breakdown of asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans. GO:0036184 asperthecin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036184 asperthecin synthesis|asperthecin formation|asperthecin biosynthesis The chemical reactions and pathways resulting in the formation of asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans. CHEBI:90820 11(R)-HEPE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90820 GO:0036185 13-lipoxin reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036185 Reactome:R-HSA-2161844 Definition: Catalysis of the reaction: 15-oxolipoxin A4 + NAD(P)H + H+ = 13,14-dihydro-15-oxolipoxin A4 + NAD(P)+. GO:0036186 early phagosome membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036186 early phagocytic vesicle membrane The lipid bilayer surrounding an early phagosome. CHEBI:75203 2'-lauroylcardiolipin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75203 GO:0036187 cell growth mode switching, budding to filamentous biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036187 yeast to hyphal transition The process in which a cell switches from growing as a round budding cell to growing as a filament (elongated cells attached end-to-end). An example of this is the yeast-hyphal transition of Candida albicans. CHEBI:75200 phosphatidylglycerol 36:2(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75200 GO:0036188 abieta-7,13-dien-18-al dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036188 EC:1.2.1.74|KEGG_REACTION:R06357|RHEA:26225|MetaCyc:1.2.1.74-RXN abietadienal dehydrogenase Catalysis of the reaction: abieta-7,13-diene-18-al + H2O + NAD+ = abieta-7,13-diene-18-oate + NADH + H+. CHEBI:75201 2-dodecanoyl-2'-monolysocardiolipin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75201 CHEBI:75216 1-O-octadecyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75216 CHEBI:75219 1-palmitoyl-2-acetyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75219 GO:0036180 filamentous growth of a population of unicellular organisms in response to biotic stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036180 The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a biotic (living) stimulus. CHEBI:16919 creatine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16919 GO:0120116 glucagon processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120116 The formation of mature glucagon by proteolysis of the precursor proglucagon. GO:0120117 T cell meandering migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120117 lymph node surveillance|T cell meandering search The random-like motility observed for T cells in lymph nodes which enhances surveillance of antigens presented by major histocompatibility complex (MHC) molecules on antigen presenting cells (APCs). CHEBI:16918 gallate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16918 GO:0120118 flagella connector biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120118 A mobile transmembrane junction at the tip of the flagellum of some kinetoplastid species linking the tip of a new growing flagellum to an older flagellum. GO:0120119 flagellum attachment zone biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120119 FAZ A network of cytoskeletal and membranous connections responsible for the lateral attachment of the cilium to the cell body in some trypanosomatid species. CHEBI:16916 oligosaccharide phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16916 GO:0120112 UDP-glucose transmembrane transport into endoplasmic reticulum biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120112 The directed movement of UDP-glucose from cytosol to endoplasmic reticulum. GO:0036178 filamentous growth of a population of unicellular organisms in response to neutral pH biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036178 The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a neutral pH (pH close to 7) stimulus. CHEBI:16913 N-methylphenylethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16913 CHEBI:90858 alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-D-Gal-(1<->1')-N-acylsphingosine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90858 GO:0120113 cytoplasm to vacuole transport by the NVT pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120113 protein localization by the Nbr1-mediated vacuolar targeting pathway|protein localization by the NVT pathway|cytoplasm to vacuole targeting|cytoplasm-to-vacuole targeting A pathway targeting soluble cytosolic proteins to the vacuole lumen. It uses a selective autophagy receptor protein Nbr1, which is an ortholog of mammalian NBR1, and is remotely related to S. cerevisiae Cvt pathway receptor protein Atg19. Similar to the Cvt pathway, the cargos transported by this pathway are hydrolases, which presumably contribute to the hydrolytic activities in the vacuole lumen. Different from the Cvt pathway, this pathway does not require the macroautophagy machinery, but instead relies on the ESCRT machinery for cargo sequestration. This pathway is observed in the fission yeast S. pombe. GO:0036179 osteoclast maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036179 chondroclast maturation A developmental process, independent of morphogenetic (shape) change, that is required for an osteoclast cell to attain its fully functional state. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, and which typically differentiates from monocytes. CHEBI:90859 alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-D-Gal-(1<->1')-ceramide(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90859 CHEBI:16914 salicylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16914 GO:0120114 Sm-like protein family complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120114 A protein complex containing members of the Like-Sm family of proteins, which includes both the Sm proteins and the Lsm proteins, and which generally form hexameric or heptameric ring structures which bind to RNA. While some of these ring complexes may form independently of RNA, many only form in association with their target RNA. In addition to Lsm-family proteins, many of these complexes contain additional protein members. Members of this family of complexes include the snRNPs which comprise the majority of the spliceosome. Others are involved in the 5' to 3' degradation pathways of mRNAs in the cytoplasm and of unspliced transcripts in the nucleus, as well as other diverse roles. GO:0120115 Lsm2-8 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120115 IntAct:EBI-16419597 A heteroheptameric, nuclear protein complex composed of Lsm2, Lsm3, Lsm4, Lsm5, Lsm6, Lsm7, and Lsm8, or orthologs thereof, that selectively binds to snRNAs, in particular U6 or U6atac snRNAs, and also to unspliced transcripts localized within the nucleus. CHEBI:16912 trans-1,2-dithiane-4,5-diol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16912 CHEBI:16910 mandelonitrile biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16910 GO:0120110 interphase mitotic telomere clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120110 mitotic telomere clustering during interphase The process whereby the mitotic telomeres are gathered together during, or prior to, attachment to the nuclear envelope. CHEBI:90856 alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNac-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-ceramide(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90856 GO:0120111 neuron projection cytoplasm biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120111 All of the contents of a plasma membrane bounded neuron projection, excluding the plasma membrane surrounding the projection. CHEBI:90857 bacteriochlorophyllide g(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90857 GO:0036170 filamentous growth of a population of unicellular organisms in response to starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036170 The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to deprivation of nourishment. CHEBI:90850 13(S)-HODE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90850 CHEBI:75210 3,5-dihydroxyphenylglyoxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75210 GO:0036171 filamentous growth of a population of unicellular organisms in response to chemical stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036171 The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a chemical stimulus. GO:0036172 thiamine salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036172 MetaCyc:PWY-6898|MetaCyc:PWY-6897|MetaCyc:PWY-6896 A process that generates thiamine (vitamin B1) from derivatives of it without de novo synthesis. GO:0036173 thiosulfate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036173 Interacting selectively and non-covalently with the inorganic anion thiosulfate, a sulfur oxide that has formula O3S2. GO:0036174 butane monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036174 sBMO|soluble butane monooxygenase Catalysis of the reaction: butane + O2 + NAD(P)H + H+ = butanol + NAD(P)+ + H2O. GO:0036175 ribonucleoside-diphosphate reductase activity, glutaredoxin disulfide as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036175 Reactome:R-HSA-111742|Reactome:R-HSA-8866405 Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + glutaredoxin disulfide + H2O -> ribonucleoside diphosphate + glutaredoxin. GO:0036176 response to neutral pH biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036176 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a neutral pH (pH close to 7) stimulus. pH is a measure of the acidity or basicity of an aqueous solution. GO:0036177 filamentous growth of a population of unicellular organisms in response to pH biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036177 The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution. CHEBI:145497 N-acylethanolamine phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_145497 GO:0051702 biological process involved in interaction with symbiont biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051702 interaction with symbiont An interaction between two organisms living together in more or less intimate association. The term symbiont is used for the smaller (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism. GO:0051703 biological process involved in intraspecies interaction between organisms biolink:BiologicalProcess go-plus gocheck_do_not_annotate|goslim_pir http://purl.obolibrary.org/obo/GO_0051703 intraspecies interaction between organisms|intraspecies interaction with other organisms Any process in which an organism has an effect on an organism of the same species. GO:0051700 fructosyl-amino acid oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051700 FAOD activity Catalysis of the reaction: fructosyl-amino acid + O2 = corresponding amino acid + glucosone + H2O2. GO:0051701 biological process involved in interaction with host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051701 growth of symbiont in host|interaction with host|growth of symbiont in host organelle|growth of symbiont in host cell|growth of symbiont in host vacuole An interaction between two organisms living together in more or less intimate association. The term host is used for the larger (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism. GO:0051706 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051706 GO:0051707 response to other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051707 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism. GO:0051704 multi-organism process biolink:BiologicalProcess go-plus gocheck_do_not_annotate|goslim_pir http://purl.obolibrary.org/obo/GO_0051704 physiological interaction with other organism|interaction between organisms|physiological interaction between organisms A biological process which involves another organism of the same or different species. CHEBI:16908 NADH biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16908 GO:0051705 obsolete multi-organism behavior biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0051705 behavioural interaction between organisms|behavioral signalling|behavioral signaling|behavioral interaction between organisms|behavioural interaction with other organism|behavioral interaction with other organism OBSOLETE. Any process in which an organism has a behavioral effect on another organism of the same or different species. GO:0120127 response to zinc ion starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120127 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of zinc ion. CHEBI:16907 4-nitroquinoline N-oxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16907 GO:0051708 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051708 CHEBI:16904 fluoren-9-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16904 CHEBI:16905 keto-D-fructose 1,6-bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16905 GO:0051709 regulation of killing of cells of other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051709 regulation of killing of cells of another organism|modulation by organism of apoptotic process in other organism involved in symbiotic interaction|modulation of programmed cell death in other organism|modulation of programmed cell death in other organism involved in symbiotic interaction Any process that modulates the frequency, rate or extent of the killing by an organism of cells in another organism. GO:0120123 ubiquitin activating enzyme complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120123 IntAct:EBI-16629455 E1 complex|E1 ubiquitin-activating enzyme A protein complex responsible for the catalysis of the reaction: E1 + ubiquitin + ATP--> E1-ubiquitin + AMP + PPi, where the E1-ubiquitin linkage is a thioester bond between the C-terminal glycine of Ub and a sulfhydryl side group of an E1 cysteine residue. This is the first step in a cascade of reactions in which ubiquitin is ultimately added to a protein substrate. GO:0036167 phenotypic switching in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036167 A reversible switch of a cell from one phenotype to another that occurs upon infection of a host or host cell. For example, Candida albicans switches from a unicellular form to an invasive multicellular filamentous form upon infection of host tissue. Phenotypic switching begins with changes in cell morphology and altered gene expression patterns and ends when the morphology of a population of cells has reverted back to the default state, accompanied by altered expression patterns. GO:0036168 filamentous growth of a population of unicellular organisms in response to heat biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036168 The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to an increase in temperature. CHEBI:16903 1-O-(alk-1-enyl)-2-O-acylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16903 GO:0120124 membrane fusion priming complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120124 IntAct:EBI-16411729 GATE-16 complex|LMA1 complex A protein complex that primes vacuolar or vesicular membranes for fusion with other intracellular membranes, by promoting the dissociation of cis-SNARE complexes. GO:0120125 PNGase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120125 IntAct:EBI-16422385 A protein complex responsible for the catalysis of the reaction: 4-N-(N-acetyl-D-glucosaminyl)-protein + H2O = N-acetyl-beta-D-glucosaminylamine + peptide L-aspartate. This reaction is the hydrolysis of an N4-(acetyl-beta-D-glucosaminyl)asparagine residue in which the N-acetyl-D-glucosamine residue may be further glycosylated, to yield a (substituted) N-acetyl-beta-D-glucosaminylamine and the peptide containing an aspartic residue. GO:0036169 3-methoxy-4-hydroxy-5-decaprenylbenzoic acid decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036169 Reactome:R-HSA-2162195 Catalysis of the reaction: 3-methoxy-4-hydroxy-5-decaprenylbenzoic acid -> 2-methoxy-6-decaprenylphenol + CO2. CHEBI:90849 geranylgeranyl bacteriochlorophyllide a(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90849 CHEBI:16900 chlorophyllide a biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16900 GO:0120126 response to copper ion starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120126 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of copper ion. CHEBI:16901 alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16901 GO:0120120 bilobe structure biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120120 kinetoplastid flagellar hook complex A cytoskeletal structure in some kinetoplastid species linking the structures of the ciliary pocket collar and the flagellum attachment zone (aka cilium attachment zone). GO:0120121 tripartite attachment complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120121 TAC A three-part cytoskeletal structure in kinetoplastid species linking mitochondrial DNA organised in a kinetoplast through the mitochondrial membranes to the basal body. GO:0120122 prolactin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120122 prolactin metabolism The chemical reactions and pathways involving prolactin, a protein hormone of the anterior pituitary gland that promotes lactation in response to the suckling stimulus of hungry young mammals. CHEBI:75220 1-stearoyl-2-acetyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75220 GO:0036160 melanocyte-stimulating hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036160 MSH secretion The regulated release of a melanocyte-stimulating hormone, any of a group of peptide hormones that are produced by cells in the intermediate lobe of the pituitary gland, and stimulate the production of melanin to increase pigmentation. CHEBI:90840 O-(N-acetyl-beta-D-glucosaminyl)-L-threonine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90840 GO:0036161 calcitonin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036161 The regulated release of calcitonin, a peptide hormone that participates in calcium and phosphorus metabolism, from a cell. GO:0036162 oxytocin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036162 The regulated release of oxytocin, a cyclic nonapeptide hormone with amino acid sequence CYIQNCPLG that also acts as a neurotransmitter in the brain, from a cell. Oxytocin is the principal uterine-contracting and milk-ejecting hormone of the posterior pituitary, and together with the neuropeptide vasopressin, is believed to influence social cognition and behavior. GO:0036163 3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036163 RHEA:44768|KEGG_REACTION:R06866 Catalysis of the reaction: 3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid -> 2-hexaprenyl-6-methoxyphenol + CO2. GO:0036164 cell-abiotic substrate adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036164 cell-abiotic surface adhesion The attachment of a cell to an underlying abiotic (non-living) substrate via adhesion molecules. GO:0036165 invasive growth in response to heat biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036165 invasive growth in response to high temperature|invasive growth in response to elevated temperature|invasive growth in response to temperature stimulus The growth of colonies in filamentous chains of cells as a result of an increase in temperature. GO:0036166 phenotypic switching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036166 phenotypic dimorphism A reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations. Phenotypic switching involves changes in cell morphology and altered gene expression patterns. For example, Candida albicans switches from white cells to opaque cells for sexual mating. Phenotypic switching also occurs in multicellular organisms; smooth muscle cells (SMCs) exhibit phenotypic transitions to allow rapid adaption to fluctuating environmental cues. CHEBI:75239 1-acyl-2-palmitoleoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75239 GO:0051710 regulation of cytolysis in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051710 regulation of cytolysis of cells of another, non-host, organism|regulation of cytolysis of cells of another organism Any process that modulates the frequency, rate or extent of the cytolysis by an organism of cells in another organism. CHEBI:75238 1-acyl-2-oleoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75238 GO:0051713 negative regulation of cytolysis in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051713 down regulation of cytolysis of cells of another organism|inhibition of cytolysis of cells of another organism|negative regulation of cytolysis of cells of another organism|down-regulation of cytolysis of cells of another organism|negative regulation of cytolysis of cells of another, non-host, organism|downregulation of cytolysis of cells of another organism Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the cytolysis of cells in another organism. GO:0051714 positive regulation of cytolysis in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051714 upregulation of cytolysis of cells of another organism|positive regulation of cytolysis of cells of another organism|stimulation of cytolysis of cells of another organism|activation of cytolysis of cells of another organism|up-regulation of cytolysis of cells of another organism|positive regulation of cytolysis of cells of another, non-host, organism|up regulation of cytolysis of cells of another organism Any process that activates or increases the frequency, rate or extent of the cytolysis by an organism of cells in another organism. GO:0051711 negative regulation of killing of cells of other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051711 downregulation of killing of cells of another organism|down regulation of killing of cells of another organism|inhibition of killing of cells of another organism|negative regulation of killing of cells of another organism|down-regulation of killing of cells of another organism|negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction Any process that stops, prevents, or reduces the frequency, rate or extent of the killing by an organism of cells in another organism. GO:0051712 positive regulation of killing of cells of other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051712 positive regulation by organism of non-apoptotic programmed cell death in other organism during symbiotic interaction|upregulation of killing of cells of another organism|activation by organism of apoptotic programmed cell death in other organism during symbiotic interaction|induction by organism of apoptosis in other organism involved in symbiotic interaction|stimulation of killing of cells of another organism|activation of killing of cells of another organism|up-regulation of killing of cells of another organism|positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction|enhancement of other organism programmed cell death by organism|positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction|induction by organism of apoptosis in other organism during symbiotic interaction|up regulation of killing of cells of another organism Any process that activates or increases the frequency, rate or extent of the killing by an organism of cells in another organism. GO:0051717 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051717 Reactome:R-HSA-1855200|Reactome:R-HSA-1855205|MetaCyc:3.1.3.62-RXN inositol 1,3,4,5-tetrakisphosphate 3-phosphomonoesterase activity|inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase activity|inositol 1,3,4,5-tetrakisphosphate-5-phosphomonoesterase activity Catalysis of the reaction: inositol-1,3,4,5-tetrakisphosphate + H2O = inositol-1,4,5-trisphosphate + phosphate. GO:0051718 DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051718 Reactome:R-HSA-5334151 HpaII methylase|M.BsuRIb|M.BsuRIa|HpaII' methylase Catalysis of the reaction: S-adenosyl-L-methionine + CpG (in DNA) = S-adenosyl-L-homocysteine + 5-MeCpG (in DNA). GO:0051715 cytolysis in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051715 cytolysis of cells of another organism|cytolysis of cells of competing organism|cytolysis of cells of another, non-host, organism The killing by an organism of a cell in another organism by means of the rupture of cell membranes and the loss of cytoplasm. GO:0051716 cellular response to stimulus biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0051716 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell. GO:0051719 DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051719 Reactome:R-HSA-5334152|Reactome:R-HSA-5334097 Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing CpN = S-adenosyl-L-homocysteine + DNA containing 5-MeCpN. GO:0036156 inner dynein arm biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036156 inner dynein arm complex Inner arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. The structure of inner dynein arms is complex and may vary within the axoneme. Inner dynein arms are heteromeric, comprising 8 different heavy chains and various subunits. Inner and outer dynein arms have different functions in the generation of microtubule-based motility. GO:0036157 outer dynein arm biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036157 outer dynein arm complex Outer arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. Outer dynein arms contain 2-3 heavy chains, two or more intermediate chains and a cluster of 4-8 light chains. Inner and outer dynein arms have different functions in the generation of microtubule-based motility. GO:0036158 outer dynein arm assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036158 ODA assembly The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein outer arm, an outer arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. GO:0036159 inner dynein arm assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036159 IDA assembly The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein inner arm, an inner arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. CHEBI:75231 12-oxo-ETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75231 CHEBI:90872 L-thyroxine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90872 CHEBI:90873 dehydroalanine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90873 CHEBI:75232 (8R)-hydroxy-(11R,12R)-epoxyicosa-(5Z,9E,14Z)-trienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75232 GO:0036150 phosphatidylserine acyl-chain remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036150 phosphatidyl-L-serine acyl-chain remodeling Remodeling the acyl chains of phosphatidylserine, through sequential deacylation and re-acylation reactions, to generate phosphatidylserine containing different types of fatty acid acyl chains. CHEBI:90874 3,3',5-triiodo-L-thyronine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90874 GO:0036151 phosphatidylcholine acyl-chain remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036151 Remodeling the acyl chains of phosphatidylcholine, through sequential deacylation and re-acylation reactions, to generate phosphatidylcholine containing different types of fatty acid acyl chains. CHEBI:75230 12(R)-HPETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75230 GO:0036152 phosphatidylethanolamine acyl-chain remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036152 Remodeling the acyl chains of phosphatidylethanolamine, through sequential deacylation and re-acylation reactions, to generate phosphatidylethanolamine containing different types of fatty acid acyl chains. CHEBI:75235 (13R)-hydroxy-(14S,15S)-epoxyicosa-(5Z,8Z,11Z)-trienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75235 GO:0036153 triglyceride acyl-chain remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036153 triacylglycerol acyl-chain remodeling Remodeling the acyl chains of triacylglycerol, through sequential deacylation and re-acylation reactions, to generate triacylglycerol containing different types of fatty acid acyl chains. GO:0036154 diacylglycerol acyl-chain remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036154 diglyceride acyl-chain remodeling Remodeling the acyl chains of diacylglycerol, through sequential deacylation and re-acylation reactions, to generate diacylglycerol containing different types of fatty acid acyl chains. CHEBI:90870 3-iodo-L-tyrosine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90870 CHEBI:75233 (8R)-hydroxy-(11S,12S)-epoxyicosa-(5Z,9E,14Z)-trienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75233 CHEBI:75234 (10R)-hydroxy-(11S,12S)-epoxyicosa-(5Z,8Z,14Z)-trienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75234 GO:0036155 acylglycerol acyl-chain remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036155 glyceride acyl-chain remodeling Remodeling the acyl chains of an acylglycerol, through sequential deacylation and re-acylation reactions, to generate an acylglycerol containing different types of fatty acid acyl chains. CHEBI:90871 3,5-diiodo-L-tyrosine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90871 GO:0051720 DNA (cytosine-5-)-methyltransferase activity, acting on CpNpG substrates biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051720 Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing CpNpG = S-adenosyl-L-homocysteine + DNA containing 5-MeCpNpG. GO:0051721 protein phosphatase 2A binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051721 protein phosphatase 2 binding Interacting selectively and non-covalently with the enzyme protein phosphatase 2A. GO:0051724 NAD transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051724 NADH transporter activity|NAD+ transporter activity|NAD (oxidized) transporter activity|oxidized nicotinamide adenine dinucleotide transmembrane transporter activity|NAD (reduced) transporter activity|oxidized NAD transporter activity|reduced nicotinamide adenine dinucleotide transmembrane transporter activity|reduced NAD transporter activity|nicotinamide adenine dinucleotide transmembrane transporter activity|NAD transporter activity Enables the transfer of NAD from one side of a membrane to the other. GO:0051725 protein de-ADP-ribosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051725 removal of ADP-ribose from protein|protein poly(ADP-ribose) catabolism|protein poly(ADP-ribose) degradation|protein poly(ADP-ribose) catabolic process|protein poly(ADP-ribose) hydrolysis|protein amino acid de-ADP-ribosylation|poly(ADP-ribose) removal from protein The process of removing one or more ADP-ribose residues from a protein. GO:0051722 protein C-terminal methylesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051722 Reactome:R-HSA-8856951 protein phosphatase methylesterase activity Catalysis of the reaction: C-terminal protein amino acid methyl ester + H2O = protein amino acid + methanol. GO:0051723 protein methylesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051723 Reactome:R-HSA-5367022 PME activity|protein methyl-esterase activity|protein carboxylic ester hydrolase activity|protein carboxyl methylesterase activity Catalysis of the reaction: protein amino acid methyl ester + H2O = protein amino acid + methanol. GO:0051728 cell cycle switching, mitotic to meiotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051728 cell cycle switching, mitosis to meiosis|initiation of meiosis|initiation of meiotic cell cycle|conversion to meiotic cell cycle|entry into meiosis|conversion to meiosis|entry into meiotic cell cycle|meiotic entry The process in which a cell switches cell cycle mode from mitotic to meiotic division. GO:0051729 germline cell cycle switching, mitotic to meiotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051729 germline entry into meiotic cell cycle|germline cell cycle switching, mitosis to meiosis|germline conversion to meiosis|germline meiotic entry|germline initiation of meiotic cell cycle|germline initiation of meiosis|germline conversion to meiotic cell cycle|germline entry into meiosis The process in which a germline cell switches cell cycle mode from mitotic to meiotic division. GO:0051726 regulation of cell cycle biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0051726 cell cycle regulation|regulation of progression through cell cycle|regulation of cell cycle progression|cell cycle modulation|control of cell cycle progression|modulation of cell cycle progression|cell cycle regulator|tumor suppressor Any process that modulates the rate or extent of progression through the cell cycle. GO:0051727 obsolete cell cycle switching, meiotic to mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051727 entry into mitotic cell cycle|cell cycle switching, meiotic to mitotic cell cycle|entry into mitosis|initiation of mitotic cell cycle|cell cycle switching, meiosis to mitosis|conversion to mitosis|mitotic entry|conversion to mitotic cell cycle|initiation of mitosis OBSOLETE. The process in which a cell switches cell cycle mode from meiotic to mitotic division. CHEBI:145470 sophoroside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_145470 GO:0036145 dendritic cell homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036145 DC homeostasis The process of regulating the proliferation and elimination of dendritic cells such that the total number of dendritic cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. CHEBI:90869 validamycin A(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90869 GO:0036146 cellular response to mycotoxin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036146 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycotoxin stimulus. A mycotoxin is a toxic chemical substance produced by fungi. GO:0036147 rumination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036147 digestive rumination A digestive process in which food, usually grass or hay, is swallowed into a multi-compartmented stomach, regurgitated, chewed again, and swallowed again. GO:0036148 phosphatidylglycerol acyl-chain remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036148 Remodeling the acyl chains of phosphatidylglycerol, through sequential deacylation and re-acylation reactions, to generate phosphatidylglycerol containing different types of fatty acid acyl chains. GO:0036149 phosphatidylinositol acyl-chain remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036149 Remodeling the acyl chains of phosphatidylinositol, through sequential deacylation and re-acylation reactions, to generate phosphatidylinositol containing different types of fatty acid acyl chains. CHEBI:90866 14-HDoHE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90866 CHEBI:90867 14-oxo-DoHE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90867 CHEBI:90868 validamycin B biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90868 CHEBI:75242 1-acyl-2-oleoyl-sn-glycero-3-phosphoserine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75242 CHEBI:75243 1-acyl-2-arachidonoyl-sn-glycero-3-phospho-1D-myo-inositol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75243 CHEBI:90862 alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90862 CHEBI:75240 1-acyl-2-palmitoleoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75240 GO:0036140 peptidyl-asparagine 3-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036140 Catalysis of the reaction: peptidyl L-asparagine + 2-oxoglutarate + O2 = peptidyl 3-hydroxy-L-asparagine + succinate + CO2. CHEBI:75241 1-acyl-2-palmitoleoyl-sn-glycero-3-phosphoserine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75241 GO:0036141 L-phenylalanine-oxaloacetate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036141 L-phenylalanine:oxaloacetate transaminase activity Catalysis of the reaction L-phenylalanine + oxaloacetate = phenylpyruvate + aspartate. GO:0036142 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0036142 CHEBI:75244 aklaviketone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75244 GO:0036143 kringle domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036143 Interacting selectively and non-covalently with a kringle domain. Kringle domains are protein domains that fold into large loops stabilized by 3 disulfide linkages, and are important in protein-protein interactions with blood coagulation factors. CHEBI:75245 1-O-octadecyl-2-arachidonoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75245 GO:0036144 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0036144 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051731 PNK|5'-dephosphopolynucleotide kinase activity|polynucleotide kinase activity|polynucleotide 5'-hydroxy-kinase activity|polynucleotide 5'-hydroxyl kinase (phosphorylating) activity|5'-hydroxyl polynucleotide kinase activity Catalysis of the reaction: NTP + 5'-dephosphopolynucleotide = NDP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA. GO:0051732 polyribonucleotide kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051732 RNA 5'-hydroxyl kinase activity|5'-hydroxyl RNA kinase activity|5'-hydroxyl polyribonucleotide kinase activity|RNA kinase activity Catalysis of the reaction: NTP + 5'-dephospho-RNA = NDP + 5'-phospho-RNA. GO:0051730 GTP-dependent polyribonucleotide 5'-hydroxyl-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051730 GTP-dependent RNA kinase activity|GTP-dependent polyribonucleotide kinase activity|GTP:5'-dephosphopolyribonucleotide 5'-phosphotransferase activity|GTP-dependent polynucleotide 5'-hydroxyl-kinase activity|GTP-dependent RNA 5'-hydroxyl-kinase activity Catalysis of the reaction: GTP + 5'-dephospho-RNA = GDP + 5'-phospho-RNA. GO:0051735 GTP-dependent polynucleotide kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051735 GTP-dependent polynucleotide 5'-hydroxyl-kinase activity|GTP:5'-dephosphopolynucleotide 5'-phosphotransferase activity Catalysis of the reaction: GTP + 5'-dephosphopolynucleotide = GDP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA. GO:0051736 ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051736 ATP:5'-dephosphopolyribonucleotide 5'-phosphotransferase activity|ATP-dependent RNA 5'-hydroxyl-kinase activity|ATP-dependent RNA kinase activity|ATP-dependent polyribonucleotide kinase activity|ATP-dependent polynucleotide 5'-hydroxyl-kinase activity Catalysis of the reaction: ATP + 5'-dephospho-RNA = ADP + 5'-phospho-RNA. GO:0051733 polydeoxyribonucleotide kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051733 DNA kinase activity|DNA 5'-hydroxyl kinase activity Catalysis of the reaction: NTP + 5'-dephospho-DNA = NDP + 5'-phospho-DNA. GO:0051734 ATP-dependent polynucleotide kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051734 EC:2.7.1.78|RHEA:54580 ATP:5'-dephosphopolynucleotide 5'-phosphotransferase activity|ATP-dependent polynucleotide 5'-hydroxyl-kinase activity|ATP:5'-dephosphopolynucleotide 5'-phosphatase activity Catalysis of the reaction: ATP + 5'-dephosphopolynucleotide = ADP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA. GO:0075705 obsolete viral entry into host cell via clathrin-mediated endocytosis followed by genetic injection through the endosome membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075705 viral penetration via endocytosis followed by genetic injection through the endosome membrane|viral entry into host cell via clathrin-mediated endocytosis followed by genetic injection through the endosome membrane OBSOLETE. The uptake of a virus into a host cell that begins by invagination of a specific region of the host cell plasma membrane around the bound virus to form a clathrin-coated pit, which then pinches off to form a clathrin-coated endocytic vesicles containing the virus. The vesicle then delivers its viral content to early endosomes, and the process ends when the viral nucleic acid is released into the host cytoplasm by its injection through the endosome membrane. GO:0075706 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075706 GO:0051739 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051739 GO:0051737 GTP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051737 GTP-dependent polynucleotide 5'-hydroxyl-kinase activity|GTP:5'-dephosphopolydeoxyribonucleotide 5'-phosphotransferase activity|GTP-dependent DNA 5'-hydroxyl-kinase activity|GTP-dependent DNA kinase activity|GTP-dependent polydeoxyribonucleotide kinase activity Catalysis of the reaction: GTP + 5'-dephospho-DNA = GDP + 5'-phospho-DNA. GO:0051738 xanthophyll binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051738 Interacting selectively and non-covalently with xanthophylls, any of several neutral yellow to orange carotenoid pigments containing oxygen. GO:0036134 12-hydroxyheptadecatrienoic acid synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036134 RHEA:48644|Reactome:R-HSA-2161613 prostaglandin H2 degradation activity Catalysis of the reaction: prostaglandin H2 = 12-hydroxyheptadecatrienoic acid (HHT) + malonaldehyde (MDA). GO:0036135 Schwann cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036135 The orderly movement of a Schwann cell from one site to another. A Schwann cell is a glial cell that ensheathes axons of neuron in the peripheral nervous system and is necessary for their maintainance and function. GO:0036136 kynurenine-oxaloacetate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036136 L-kynurenine-oxaloacetate transaminase activity Catalysis of the reaction: L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-aspartate. GO:0036137 kynurenine aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036137 kynurenine-oxo-acid transaminase activity|L-kynurenine transaminase activity Catalysis of the transfer of an amino group from kynurenine to an acceptor, usually a 2-oxo acid. GO:0036138 peptidyl-histidine hydroxylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036138 The hydroxylation of peptidyl-histidine to form peptidyl-hydroxyhistidine. CHEBI:90898 protoviolaceinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90898 CHEBI:90899 violaceinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90899 GO:0036139 peptidyl-histidine dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036139 Catalysis of the reaction: peptidyl L-histidine + 2-oxoglutarate + O2 = peptidyl hydroxy-L-histidine + succinate + CO2. CHEBI:90894 (-)-5'-desmethylyatein biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90894 CHEBI:90896 (-)-pluviatolide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90896 CHEBI:90897 protoviolaceinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90897 GO:0036130 prostaglandin H2 endoperoxidase reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036130 RHEA:45312|KEGG_REACTION:R02264|Reactome:R-HSA-2161549 PGH2 9-,11-endoperoxide reductase|PGH2 9,11-endoperoxidase Catalysis of the reaction: prostaglandin H2 + NADPH + H+ -> prostaglandin F2alpha + NADP+. This reaction is the reduction of prostaglandin H2 ((5Z,13E)-(15S)-9alpha,11alpha-Epidioxy-15-hydroxyprosta-5,13-dienoate) to prostaglandin F2alpha ((5Z,13E)-(15S)-9alpha,11alpha,15-Trihydroxyprosta-5,13-dienoate). CHEBI:75257 1-O-(alk-1-enyl)-2-palmitoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75257 CHEBI:90890 3-farnesyl-3-hydroxy-2-methyl-1-oxo-1lambda(5)-quinolin-4-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90890 GO:0036131 prostaglandin D2 11-ketoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036131 Reactome:R-HSA-2161614|EC:1.1.1.188|RHEA:45316|KEGG_REACTION:R02799 PGD2 11-ketoreductase|prostaglandin 11-keto reductase Catalysis of the reaction: prostaglandin D2 + H+ + NADPH -> 11-epi-prostaglandin F2alpha + NADP+. CHEBI:90891 2-imino-3-(indol-3-yl)propanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90891 GO:0036132 13-prostaglandin reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036132 KEGG_REACTION:R04557|KEGG_REACTION:R04556|EC:1.3.1.48|Reactome:R-HSA-2161692 15-oxo-delta13-prostaglandin reductase activity|15-oxoprostaglandin 13-reductase activity|prostaglandin delta13-reductase activity|prostaglandin 13-reductase activity|15-ketoprostaglandin delta13-reductase activity|delta13-15-ketoprostaglandin reductase activity Catalysis of the reaction: 15-keto-prostaglandin + NAD(P)H + H+ -> 13,14-dihydro-15-keto-prostaglandin + NAD(P)+. This reaction is the reduction of 15-keto-prostaglandin. CHEBI:75255 1-O-(alk-1-enyl)-2-octanoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75255 CHEBI:90892 2-imino-3-(indol-3-yl)propanoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90892 GO:0036133 11-hydroxythromboxane B2 dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036133 Reactome:R-HSA-2161732|KEGG_REACTION:R05060|RHEA:52312 NAD dependent 11-hydroxythromboxane B2 dehydrogenase activity Catalysis of the reaction: thromboxane B2 + NAD+ = 11-dehydro-thromboxane B2 + NADH + H+. CHEBI:90893 (-)-bursehernin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90893 CHEBI:75256 1-O-(alk-1-enyl)-2-stearoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75256 GO:0051742 2-methyl-6-solanyl-1,4-benzoquinone methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051742 MetaCyc:RXN-2762|RHEA:37999 MSBQ methyltransferase activity Catalysis of the reaction: 2-methyl-6-solanyl-1,4-benzoquinone + S-adenosyl-methionine = 2,3-dimethyl-6-solanyl-1,4-benzoquinone + S-adenosyl-homocysteine. GO:0051743 red chlorophyll catabolite reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051743 MetaCyc:RXN-7741|RHEA:24752 RCC reductase activity Catalysis of the reaction: red chlorophyll catabolite + reduced ferredoxin + 2 H+ = primary fluorescent catabolite + oxidized ferredoxin. This reaction is the reduction of the C20/C1 double bond in the pyrrole system of red chlorophyll catabolite (RCC) to a colorless tetrapyrrole (pFCC) with a strong blue fluorescence. GO:0051740 ethylene binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051740 ethene binding Interacting selectively and non-covalently with ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator. GO:0051741 2-methyl-6-phytyl-1,4-benzoquinone methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051741 MetaCyc:RXN-2542|RHEA:37979 MPBQ methyltransferase activity Catalysis of the reaction: 2-methyl-6-phytyl-1,4-benzoquinone + S-adenosyl-methionine = 2,3-dimethyl-6-phytyl-1,4-benzoquinone + S-adenosyl-homocysteine. GO:0051746 thalianol synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051746 EC:5.4.99.31|RHEA:26163 Catalysis of the cyclization of 3(S)-oxidosqualene to (3S,13S,14R)-malabarica-8,17,21-trien-3-ol (thalianol). GO:0051747 cytosine C-5 DNA demethylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051747 DNA methyltransferase activity acting on cytosine C-5|hydrolytic DNA demethylase activity|DNA demethylase activity Catalysis of the reaction: methyl-dCpdG DNA + H2O = dCpdG DNA + methanol. This reaction is the hydrolytic removal of the methyl group on the 5 position of cytosine in DNA. CHEBI:89891 3-hexanone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_89891 GO:0051744 3,8-divinyl protochlorophyllide a 8-vinyl reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051744 MetaCyc:RXN1F-72|RHEA:48884 Catalysis of the reaction: divinyl protochlorophyllide a + NADPH + H+ = monovinyl protochlorophyllide a + NADP+. GO:0051745 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051745 MetaCyc:ISPH2-RXN|EC:1.17.1.2 4-hydroxy-3-methylbut-2-enyl diphosphate reductase activity|isopentenyl-diphosphate:NAD(P)+ oxidoreductase activity Catalysis of the reaction: (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H + H+ = isopentenyl diphosphate + NAD(P)+ + H2O. Note that (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate is an alternative name for 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. GO:0051748 UTP-monosaccharide-1-phosphate uridylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051748 MetaCyc:2.7.7.64-RXN|RHEA:13205|EC:2.7.7.64 UDP-monosaccharide pyrophosphorylase activity|UDP-monosaccharide diphosphorylase activity|USP|PsUSP|UDP-sugar pyrophosphorylase activity Catalysis of the reaction: UTP + a monosaccharide 1-phosphate = diphosphate + UDP-monosaccharide. GO:0051749 indole acetic acid carboxyl methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051749 IAA carboxyl methyltransferase activity Catalysis of the reaction: indole acetic acid + S-adenosyl-methionine = methyl indole acetic acid ester + S-adenosyl-homocysteine. PR:000013429 parathyroid hormone biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000013429 parathyrin|parathormone|PTH A protein that is a translation product of the human PTH gene or a 1:1 ortholog thereof. GO:0036123 histone H3-K9 dimethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036123 histone H3 K9 dimethylation|histone lysine H3 K9 dimethylation The modification of histone H3 by addition of two methyl groups to lysine at position 9 of the histone. GO:0036124 histone H3-K9 trimethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036124 The modification of histone H3 by addition of three methyl groups to lysine at position 9 of the histone. GO:0036125 fatty acid beta-oxidation multienzyme complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036125 A multienzyme complex possessing three kinds of enzymes that catalyze the chain reactions in the fatty acid beta-oxidation cycle, enoyl-CoA hydratase (ECH), 3-hydroxyacyl-CoA dehydrogenase (HACD), and acetyl-CoA C-acyltransferase (KACT). GO:0036126 sperm flagellum biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036126 sperm cilium|sperm tail A microtubule-based flagellum (or cilium) that is part of a sperm, a mature male germ cell that develops from a spermatid. CHEBI:90887 2-hydroxy-6-oxo-2,4-heptadienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90887 GO:0036127 3-sulfino-L-alanine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036127 cysteine sulfinate binding Interacting selectively and non-covalently with 3-sulfino-L-alanine (cysteine sulfinate). GO:0036128 CatSper complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036128 CatSper channel complex|CATSPER channel A sperm-specific voltage-gated calcium channel that controls the intracellular calcium ion concentration and, thereby, the swimming behavior of sperm. Consists of a heteromeric tetramer surrounding a calcium ion- selective pore. May also contain additional auxiliary subunits. CHEBI:90888 aurachin C biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90888 GO:0036129 obsolete negative regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036129 OBSOLETE. Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hydrogen peroxide (H2O2) stimulus. CHEBI:90889 aurachin C epoxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90889 CHEBI:75264 1-acyl-2-stearoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75264 CHEBI:90883 2,3-dichloromuconate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90883 CHEBI:90884 2'-hydroxyrifampicin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90884 CHEBI:75265 1-acyl-2-palmitoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75265 CHEBI:90885 1,3,7-trimethyl-5-hydroxyisouric acid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90885 CHEBI:90886 2-hydroxy-6-oxo-2,4-heptadienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90886 CHEBI:75263 1-acyl-2-octanoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75263 CHEBI:75268 1-O-hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75268 GO:0036120 cellular response to platelet-derived growth factor stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036120 cellular response to PDGF stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus. GO:0036121 double-stranded DNA helicase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036121 double-stranded DNA-dependent ATP-dependent DNA helicase activity|dsDNA-dependent ATPase activity|double-stranded DNA-dependent ATPase activity|dsDNA-dependent ATP-dependent DNA helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of double-stranded DNA; drives the unwinding of a DNA helix. CHEBI:75266 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75266 CHEBI:90882 3,4-dichlorocatechol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90882 GO:0036122 BMP binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036122 bone morphogenetic protein binding Interacting selectively and non-covalently with a member of the bone morphogenetic protein (BMP) family. NCBITaxon:4932 Saccharomyces cerevisiae organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_4932 Saccharomyces uvarum var. melibiosus|baker's yeast|brewer's yeast|Mycoderma cerevisiae|Saccharomyces oviformis|Saccharomyces italicus|S. cerevisiae|Candida robusta|Saccharomyces capensis NCBITaxon:4930 Saccharomyces organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_4930 Pachytichospora CHEBI:16858 pantetheine 4'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16858 CHEBI:16859 oxaloacetic acid 4-methyl ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16859 CHEBI:16856 glutathione biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16856 CHEBI:16857 L-threonine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16857 GO:0002908 regulation of peripheral B cell deletion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002908 Any process that modulates the frequency, rate, or extent of peripheral B cell deletion. CHEBI:16854 3-fumarylpyruvate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16854 GO:0002909 negative regulation of peripheral B cell deletion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002909 down-regulation of peripheral B cell deletion|downregulation of peripheral B cell deletion|down regulation of peripheral B cell deletion|inhibition of peripheral B cell deletion Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral B cell deletion. CHEBI:16855 D-lysine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16855 CHEBI:16852 L-dopaquinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16852 CHEBI:16853 tetrathionic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16853 GO:0002904 positive regulation of B cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002904 up regulation of B cell apoptosis|upregulation of B cell apoptosis|stimulation of B cell apoptosis|activation of B cell apoptosis|up-regulation of B cell apoptosis|positive regulation of B cell apoptosis Any process that activates or increases the frequency, rate, or extent of B cell apoptotic process. CHEBI:16850 1,2-dihydro-alpha-santonin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16850 GO:0002905 regulation of mature B cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002905 regulation of mature B cell apoptosis Any process that modulates the frequency, rate, or extent of mature B cell apoptotic process. CHEBI:16851 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16851 GO:0002906 negative regulation of mature B cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002906 down-regulation of mature B cell apoptosis|inhibition of mature B cell apoptosis|down regulation of mature B cell apoptosis|downregulation of mature B cell apoptosis|negative regulation of mature B cell apoptosis Any process that stops, prevents, or reduces the frequency, rate, or extent of mature B cell apoptotic process. GO:0002907 positive regulation of mature B cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002907 activation of mature B cell apoptosis|stimulation of mature B cell apoptosis|up-regulation of mature B cell apoptosis|upregulation of mature B cell apoptosis|positive regulation of mature B cell apoptosis|up regulation of mature B cell apoptosis Any process that activates or increases the frequency, rate, or extent of mature B cell apoptotic process. GO:0002900 positive regulation of central B cell deletion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002900 up regulation of central B cell deletion|activation of central B cell deletion|stimulation of central B cell deletion|up-regulation of central B cell deletion|upregulation of central B cell deletion Any process that activates or increases the frequency, rate, or extent of central B cell deletion. GO:0002901 mature B cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002901 apoptosis of mature B-lymphocytes|apoptosis of mature B-cells|mature B lymphocyte programmed cell death by apoptosis|mature B lymphocyte apoptosis|programmed cell death of mature B-cells by apoptosis|mature B cell programmed cell death by apoptosis|programmed cell death, mature B lymphocytes|programmed cell death of mature B-lymphocytes by apoptosis|programmed cell death, mature B cells|mature B-lymphocyte programmed cell death by apoptosis|apoptosis of mature B lymphocytes|programmed cell death of mature B cells by apoptosis|mature B-cell apoptosis|mature B-cell programmed cell death by apoptosis|apoptosis of mature B cells|programmed cell death, mature B-lymphocytes|mature B-lymphocyte apoptosis|programmed cell death of mature B lymphocytes by apoptosis|programmed cell death, mature B-cells|mature B cell apoptosis Any apoptotic process in a B cell that is mature, having left the bone marrow. GO:0002902 regulation of B cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002902 regulation of B cell apoptosis Any process that modulates the frequency, rate, or extent of B cell apoptotic process. GO:0002903 negative regulation of B cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002903 downregulation of B cell apoptosis|down regulation of B cell apoptosis|inhibition of B cell apoptosis|negative regulation of B cell apoptosis|down-regulation of B cell apoptosis Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell apoptotic process. GO:0002910 positive regulation of peripheral B cell deletion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002910 upregulation of peripheral B cell deletion|stimulation of peripheral B cell deletion|up-regulation of peripheral B cell deletion|activation of peripheral B cell deletion|up regulation of peripheral B cell deletion Any process that activates or increases the frequency, rate, or extent of peripheral B cell deletion. CHEBI:16849 D-fructuronate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16849 CHEBI:16848 coenzyme gamma-F420-2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16848 CHEBI:16845 (S)-2,3,4,5-tetrahydrodipicolinate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16845 CHEBI:16846 UDP-alpha-D-galactosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16846 GO:0002919 positive regulation of peripheral B cell anergy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002919 up regulation of peripheral B cell anergy|upregulation of peripheral B cell anergy|stimulation of peripheral B cell anergy|up-regulation of peripheral B cell anergy|activation of peripheral B cell anergy Any process that activates or increases the frequency, rate, or extent of peripheral B cell anergy. CHEBI:16843 cis-1,2-dihydro-3-ethylcatechol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16843 CHEBI:16844 N(3')-acetyl-2-deoxystreptamine antibiotic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16844 CHEBI:16841 bis(3-aminopropyl)amine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16841 CHEBI:16842 formaldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16842 GO:0002915 negative regulation of central B cell anergy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002915 inhibition of central B cell anergy|down regulation of central B cell anergy|downregulation of central B cell anergy|down-regulation of central B cell anergy Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell anergy. GO:0002916 positive regulation of central B cell anergy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002916 up-regulation of central B cell anergy|upregulation of central B cell anergy|up regulation of central B cell anergy|activation of central B cell anergy|stimulation of central B cell anergy Any process that activates or increases the frequency, rate, or extent of central B cell anergy. CHEBI:16840 4-CDP-2-C-methyl-D-erythritol 2-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16840 GO:0002917 regulation of peripheral B cell anergy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002917 Any process that modulates the frequency, rate, or extent of peripheral B cell anergy. GO:0002918 negative regulation of peripheral B cell anergy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002918 downregulation of peripheral B cell anergy|down regulation of peripheral B cell anergy|inhibition of peripheral B cell anergy|down-regulation of peripheral B cell anergy Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral B cell anergy. GO:0002911 regulation of lymphocyte anergy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002911 Any process that modulates the frequency, rate, or extent of lymphocyte anergy. GO:0002912 negative regulation of lymphocyte anergy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002912 down regulation of lymphocyte anergy|downregulation of lymphocyte anergy|down-regulation of lymphocyte anergy|inhibition of lymphocyte anergy Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte anergy. GO:0002913 positive regulation of lymphocyte anergy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002913 up regulation of lymphocyte anergy|activation of lymphocyte anergy|stimulation of lymphocyte anergy|up-regulation of lymphocyte anergy|upregulation of lymphocyte anergy Any process that activates or increases the frequency, rate, or extent of lymphocyte anergy. GO:0002914 regulation of central B cell anergy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002914 Any process that modulates the frequency, rate, or extent of central B cell anergy. CHEBI:16878 N-acetyl-L-gamma-glutamyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16878 CHEBI:16879 diethyl 2-methyl-3-oxosuccinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16879 CHEBI:16877 oxidized Watasenia luciferin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16877 CHEBI:16874 psychosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16874 CHEBI:16875 5,6-dihydroxyindole-2-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16875 CHEBI:16872 N-malonylanthranilate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16872 CHEBI:16870 choline alfoscerate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16870 CHEBI:16871 4-pyridoxolactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16871 CHEBI:41808 decane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_41808 CHEBI:16869 oleandomycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16869 CHEBI:16867 D-methionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16867 CHEBI:16865 gamma-aminobutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16865 CHEBI:16866 alizarin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16866 CHEBI:16863 6-phospho-D-gluconate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16863 CHEBI:16864 D-ribofuranosyl-ADP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16864 CHEBI:16861 7''-O-phosphohygromycin B biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16861 CHEBI:16862 nucleoside diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16862 CHEBI:16860 3',4',5,7-tetrahydroxy-3-methoxyflavone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16860 CHEBI:16818 all-trans-pentaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16818 CHEBI:16816 flavonol 3-O-beta-D-glucoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16816 CHEBI:16817 trans-4-hydroxycyclohexanecarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16817 CHEBI:16814 dehydroepiandrosterone sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16814 CHEBI:16815 enol-phenylpyruvate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16815 CHEBI:16812 (S,S)-butane-2,3-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16812 CHEBI:16813 galactitol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16813 CHEBI:16810 2-oxoglutarate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16810 CHEBI:16811 methionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16811 CHEBI:16809 D-glucose 6-sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16809 CHEBI:16807 S(6)-acetyldihydrolipoamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16807 CHEBI:16808 2-dehydro-D-gluconate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16808 CHEBI:16805 [1-(5-phosphoribosyl)imidazol-4-yl]acetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16805 CHEBI:16806 xanthine-8-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16806 CHEBI:16803 N-acetylanthranilate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16803 CHEBI:16804 (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16804 CHEBI:16802 sedoheptulose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16802 NCBITaxon:4951 Yarrowia organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_4951 NCBITaxon:4952 Yarrowia lipolytica organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_4952 Mycotorula lipolytica|Candida lipolytica|Endomycopsis lipolytica CHEBI:16838 polyphosphate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16838 CHEBI:90814 17(R)-HDoHE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90814 CHEBI:16836 4-nitrophenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16836 CHEBI:90815 (4Z,7Z,10Z,14E,16Z,19Z)-13-hydroxydocosahexaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90815 CHEBI:16837 alpha-ribazole 5'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16837 CHEBI:16834 L-gamma-glutamyl-D-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16834 CHEBI:89823 PS(16:0/18:2(9Z,12Z)) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_89823 CHEBI:16835 3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16835 CHEBI:90810 5(S),11(R)-DiHETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90810 CHEBI:16832 kievitone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16832 CHEBI:90811 beta-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->4)]-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90811 CHEBI:16833 neurosporene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16833 CHEBI:90812 5(S),15(R)-DiHETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90812 CHEBI:16830 methylamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16830 CHEBI:90813 5(S),15(S)-DiHETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90813 CHEBI:89828 propyl propionate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_89828 CHEBI:16831 3-hydroxy-3-methylglutaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16831 GO:0051900 regulation of mitochondrial depolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051900 Any process that modulates the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive. GO:0051901 positive regulation of mitochondrial depolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051901 upregulation of mitochondrial depolarization|stimulation of mitochondrial depolarization|up-regulation of mitochondrial depolarization|activation of mitochondrial depolarization|up regulation of mitochondrial depolarization Any process that activates, maintains or increases the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive. GO:0051904 pigment granule transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051904 pigment granule translocation The directed movement of pigment granules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0051905 establishment of pigment granule localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051905 establishment of pigment granule localisation The directed movement of a pigment granule to a specific location. GO:0051902 negative regulation of mitochondrial depolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051902 down regulation of mitochondrial depolarization|inhibition of mitochondrial depolarization|down-regulation of mitochondrial depolarization|downregulation of mitochondrial depolarization Any process that stops, prevents, or reduces the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive. GO:0051903 S-(hydroxymethyl)glutathione dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051903 KEGG_REACTION:R06983|Reactome:R-HSA-5692237|KEGG_REACTION:R07140|EC:1.1.1.284|MetaCyc:RXN-2962|UM-BBD_reactionID:r1146 chi-ADH activity|glutathione-dependent formaldehyde dehydrogenase activity|NAD-linked formaldehyde dehydrogenase activity|NAD- and glutathione-dependent formaldehyde dehydrogenase activity|class III alcohol dehydrogenase activity|ADH3 activity|GD-FALDH activity|S-(hydroxymethyl)glutathione:NAD+ oxidoreductase activity|GS-FDH activity|FDH activity|formic dehydrogenase activity|NAD-dependent formaldehyde dehydrogenase activity Catalysis of the reaction: S-(hydroxymethyl)glutathione + NAD(P)+ = S-formylglutathione + NAD(P)H + H+. GO:0051908 double-stranded DNA 5'-3' exodeoxyribonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051908 double-stranded DNA specific 5'-3' exodeoxyribonuclease activity Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of a double-stranded DNA molecule. CHEBI:16829 polyneuridine aldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16829 GO:0051909 acetylenecarboxylate hydratase activity, producing 3-hydroxypropenoate biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051909 EC:4.2.1.27 alkynoate hydratase activity|3-hydroxypropenoate dehydratase activity|acetylenemonocarboxylate hydratase activity|acetylenecarboxylate hydratase activity Catalysis of the reaction: 3-hydroxypropenoate = propynoate + H2O. GO:0051906 maintenance of pigment granule location biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051906 maintenance of pigment granule localization Any process in which a pigment granule is maintained in a location and prevented from moving elsewhere. CHEBI:16827 corticosterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16827 GO:0051907 S-(hydroxymethyl)glutathione synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051907 UM-BBD_reactionID:r1145|EC:4.4.1.22|RHEA:22488|KEGG_REACTION:R06982|MetaCyc:RXN-2961 glutathione-dependent formaldehyde-activating enzyme activity|S-(hydroxymethyl)glutathione formaldehyde-lyase (glutathione-forming)|Gfa|S-(hydroxymethyl)glutathione formaldehyde-lyase activity Catalysis of the reaction: S-(hydroxymethyl)glutathione = formaldehyde + glutathione. CHEBI:16828 L-tryptophan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16828 CHEBI:90803 alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90803 CHEBI:16825 (R)-2-methylimino-1-phenylpropan-1-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16825 CHEBI:16826 acyl monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16826 CHEBI:16823 kanamycin A 3'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16823 CHEBI:16824 D-fuconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16824 CHEBI:16821 4-oxo-L-proline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16821 CHEBI:16822 choline sulfate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16822 CHEBI:90800 beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90800 CHEBI:90801 19-hydroxyprostaglandin H1(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90801 CHEBI:90802 alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90802 CHEBI:16820 N-benzoyl-D-arginine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16820 GO:0061280 epithelial cell migration involved in mesonephric proximal tubule morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061280 The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric proximal tubule morphogenesis. GO:0061281 specification of mesonephric connecting tubule identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061281 specification of mesonephric collecting tubule identity The process in which the connecting tubule of the mesonephric nephron acquires its identity. GO:0061282 specification of mesonephric nephron tubule identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061282 The process in which the tubules arranged along the proximal/distal axis of the mesonephric nephron acquire their identity. CHEBI:26267 proanthocyanidin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26267 GO:0061283 specification of mesonephric distal tubule identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061283 The process in which the distal tubule of the mesonephric nephron acquires its identity. GO:0061284 specification of mesonephric proximal tubule identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061284 The process in which the proximal tubule of the mesonephric nephron acquires its identity. GO:0061285 mesonephric capsule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061285 The progression of the mesonephric capsule over time, from its formation to the mature structure. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. GO:0061286 mesonephric capsule morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061286 The process in which the anatomical structures of the mesonephric capsule are generated and organized. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. GO:0061287 mesonephric capsule formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061287 The developmental process pertaining to the initial formation of a mesonephric capsule from unspecified parts. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. GO:0061288 mesonephric capsule specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061288 The regionalization process in which the identity of the mesonephric capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized. GO:0061289 Wnt signaling pathway involved in kidney development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061289 Wnt receptor signalling pathway involved in kidney development|Wnt-activated signaling pathway involved in kidney development|Wnt receptor signaling pathway involved in kidney development The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the kidney over time. CHEBI:9407 taurochenodeoxycholate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_9407 CHEBI:9402 taraxerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_9402 CHEBI:26279 propan-1-ols biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26279 CHEBI:51214 diamminedichloroplatinum biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51214 GO:0061270 mesonephric intraglomerular mesangial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061270 The multiplication or reproduction of intraglomerular glomerular mesangium cells in the mesonephros by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis. GO:0061271 mesenchymal to epithelial transition involved in mesonephric renal vesicle formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061271 A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephric renal vesicle. GO:0061272 mesonephric connecting tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061272 mesonephric collecting tubule development|mesonephric connecting duct development The process whose specific outcome is the progression of the mesonephric connecting tubule over time, from its formation to the mature structure. The mesonephric connecting tubule is a tubular segment of the mesonephric nephron; it connects the distal tubule to the collecting duct in the mesonephros. CHEBI:41893 4-deoxy-Delta(4)-beta-D-GlcpA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_41893 GO:0061273 mesonephric distal tubule morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061273 The process in which the anatomical structures of a mesonephric distal tubule are generated and organized. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the macula densa and extends to the mesonephric connecting tubule. CHEBI:26271 proline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26271 GO:0061274 mesonephric distal tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061274 The process whose specific outcome is the progression of the mesonephric distal tubule over time, from its formation to the mature structure. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the terminal segment of the proximal tubule and ends at the mesonephric connecting tubule. GO:0061275 mesonephric proximal tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061275 The progression of the mesonephric proximal tubule over time, from its formation to the mature structure. The mesonephric proximal tubule extends from the capsule to the distal tubule. CHEBI:26273 proline derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26273 GO:0061276 mesonephric proximal tubule morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061276 The process in which the anatomical structures of a mesonephric proximal tubule are generated and organized. The mesonephric proximal tubule extends from the capsule to the distal tubule. GO:0061277 mesonephric nephron tubule formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061277 The developmental process pertaining to the initial formation of a mesonephric nephron tubule from unspecified parts. A mesonephric nephron tubule is an epithelial tube that is part of a nephron in the mesonephros. GO:0061278 epithelial cell migration involved in mesonephric nephron tubule morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061278 The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric nephron tubule morphogenesis. GO:0061279 epithelial cell migration involved in mesonephric distal tubule morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061279 The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric distal tubule morphogenesis. CHEBI:9410 taurodeoxycholic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_9410 CHEBI:26248 prenyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_26248 CHEBI:26249 prenyl groups biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26249 CHEBI:26244 prenols biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26244 GO:0061290 canonical Wnt signaling pathway involved in metanephric kidney development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061290 canonical Wnt receptor signaling pathway involved in metanephric kidney development|canonical Wnt receptor signalling pathway involved in metanephric kidney development|canonical Wnt-activated signaling pathway involved in metanephric kidney development The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contribute to the progression of the metanephric kidney over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes. GO:0061291 canonical Wnt signaling pathway involved in ureteric bud branching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061291 canonical Wnt receptor signaling pathway involved in ureteric bud branching|canonical Wnt receptor signalling pathway involved in ureteric bud branching The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the branching of the ureteric bud. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes. CHEBI:26253 polyprenylhydroquinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26253 GO:0061292 canonical Wnt signaling pathway involved in mesonephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061292 canonical Wnt receptor signaling pathway involved in mesonephros development|canonical Wnt-activated signaling pathway involved in mesonephros development|canonical Wnt receptor signalling pathway involved in mesonephros development The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the mesonephros over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes. CHEBI:26254 prenylnaphthoquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_26254 GO:0061293 canonical Wnt signaling pathway involved in mesonephric nephron development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061293 canonical Wnt-activated signaling pathway involved in mesonephric nephron development|canonical Wnt receptor signaling pathway involved in mesonephric nephron development|canonical Wnt receptor signalling pathway involved in mesonephric nephron development The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contribute to the progression of the mesonephric nephron over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes. CHEBI:26255 prenylquinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26255 GO:0061294 mesonephric renal vesicle induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061294 Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the mesonephric renal vesicle. GO:0061295 regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061295 regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis|regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros. GO:0061296 negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061296 negative regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis|negative regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros. CHEBI:26250 prenol phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26250 GO:0061297 positive regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061297 positive regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis|positive regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros. GO:0061298 retina vasculature development in camera-type eye biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061298 retinal vasculature development The process whose specific outcome is the progression of the vasculature of the retina over time, from its formation to the mature structure. GO:0061299 retina vasculature morphogenesis in camera-type eye biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061299 retinal vasculature morphogenesis The process in which the vasculature of the retina is generated and organized. CHEBI:41879 dexamethasone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_41879 GO:0002940 tRNA N2-guanine methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002940 tRNA m2-guanine biosynthesis The process whereby a guanine in a tRNA is methylated at the N2 position of guanine. CHEBI:26228 precorrin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26228 GO:0002941 synoviocyte proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002941 The multiplication or reproduction of synoviocytes by cell division, resulting in the expansion of their population. A synoviocyte is a fibroblast-like cell found in synovial tissues. GO:0002942 tRNA m2,2-guanine biosynthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002942 The process whereby a guanine residue in a transfer RNA is methylated twice at the N2 position. GO:0002943 tRNA dihydrouridine synthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002943 The process whereby a uridine in a transfer RNA is converted to dihydrouridine. CHEBI:41865 sebacic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_41865 CHEBI:16899 D-mannitol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16899 CHEBI:16897 D-erythrose 4-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16897 GO:0002948 archaeosine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0002948 RHEA:54084|EC:2.6.1.97 ArcS|glutamine:preQ0-tRNA amidinotransferase Catalysis of the reaction: L-glutamine + 7-cyano-7-carbaguanine15 in tRNA + H2O = L-glutamate + archaeine15 in tRNA. CHEBI:16894 3-sulfopyruvic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16894 GO:0002949 tRNA threonylcarbamoyladenosine modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002949 t6A tRNA modification|threonylcarbamoyladenosine biosynthesis|threonylcarbamoyladenosine anabolism|threonylcarbamoyladenosine synthesis|threonylcarbamoyladenosine formation|t6A biosynthesis|t6A biosynthetic process|threonylcarbamoyladenosine biosynthetic process The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in tRNAs that decode ANN codons (where N is any base). CHEBI:16895 S-methyl-5-thio-D-ribose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16895 CHEBI:16892 4-amino-5-hydroxymethyl-2-methylpyrimidine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16892 CHEBI:16893 sphinganine 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16893 GO:0002944 cyclin K-CDK12 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0002944 CycK/Cdk12 complex A protein complex consisting of cyclin Kand cyclin-dependent kinase 12 (CDK12). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. CHEBI:16890 glycerol monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16890 GO:0002945 cyclin K-CDK13 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0002945 CycK/Cdk13 complex A protein complex consisting of cyclin Kand cyclin-dependent kinase 13 (CDK13). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. CHEBI:16891 glyoxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16891 GO:0002946 tRNA C5-cytosine methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002946 tRNA 5-methylcytosine biosynthesis The process whereby a cytosine in a tRNA is methylated at position 5 of the cytosine. GO:0002947 tumor necrosis factor receptor superfamily complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0002947 TNF receptor superfamily complex A receptor complex that contains one or more members of the tumor necrosis factor (TNF) receptor superfamily. GO:0002951 leukotriene-C(4) hydrolase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0002951 Catalysis of the reaction Leukotriene C(4) + H(2)O= leukotriene D(4) + L-glutamate. GO:0002952 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0002952 phospho-AI-2 isomerase activity Catalysis of the reaction (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione = 3-hydroxy-5-phosphonooxypentane-2,4-dione. GO:0002953 5'-deoxynucleotidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0002953 Catalysis of the reaction:a 2'-deoxyribonucleoside 5'-monophosphate + H20=a 2'-deoxyribonucleoside + phosphate. GO:0002950 ceramide phosphoethanolamine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0002950 Reactome:R-HSA-8959462 Catalysis of the reaction: CDP-ethanolamine + a ceramide = CMP + a ceramide phosphoethanolamine. CHEBI:16889 trans-3-hydroxy-L-proline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16889 CHEBI:16887 5-(4-hydroxybut-1-ynyl)-2,2'-bithiophene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16887 CHEBI:16885 1-kestose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16885 CHEBI:16886 2-aminomuconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16886 CHEBI:9457 terpinolene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_9457 CHEBI:16881 1H-indole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16881 CHEBI:16880 L-ribulose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16880 CHEBI:26207 polyterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26207 CHEBI:26208 polyunsaturated fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26208 GO:0002920 regulation of humoral immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002920 Any process that modulates the frequency, rate, or extent of a humoral immune response. GO:0002921 negative regulation of humoral immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002921 inhibition of humoral immune response|down regulation of humoral immune response|downregulation of humoral immune response|down-regulation of humoral immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response. CHEBI:26203 polyprenol triphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26203 CHEBI:41847 1,2-dioctadecanoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_41847 GO:0002926 tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002926 tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridine biosynthesis|mcm5 modification|mcm5s2U34 biosynthesis The process whereby a wobble base uridine residue in a tRNA is modified to 5-methoxycarbonylmethyl-2-thiouridine. GO:0002927 archaeosine-tRNA biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002927 The chemical reactions and pathways involved in the biosynthesis of archaeosine, an archaea-specific modified base found at position 15 in the D-loop of certain archaeal tRNAs. GO:0002928 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0002928 GO:0002929 MECO complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0002929 meta-coactivator complex A highly stable complex composed of the ATAC complex and the mediator complex (also called TRAP or MED). MECO binds and regulates the transcription of a subset of non-coding RNAs transcribed by RNA polymerase II. GO:0002922 positive regulation of humoral immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002922 up-regulation of humoral immune response|upregulation of humoral immune response|up regulation of humoral immune response|activation of humoral immune response|stimulation of humoral immune response Any process that activates or increases the frequency, rate, or extent of a humoral immune response. GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002923 Any process that modulates the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin. GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002924 down-regulation of humoral immune response mediated by circulating immunoglobulin|downregulation of humoral immune response mediated by circulating immunoglobulin|down regulation of humoral immune response mediated by circulating immunoglobulin|inhibition of humoral immune response mediated by circulating immunoglobulin Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin. GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002925 up regulation of humoral immune response mediated by circulating immunoglobulin|upregulation of humoral immune response mediated by circulating immunoglobulin|stimulation of humoral immune response mediated by circulating immunoglobulin|up-regulation of humoral immune response mediated by circulating immunoglobulin|activation of humoral immune response mediated by circulating immunoglobulin Any process that activates or increases the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin. CHEBI:26217 potassium molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26217 GO:0002930 trabecular meshwork development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002930 The progression of the trabecular meshwork over time, from its formation to the mature structure. The trabecular meshwork is a fenestrated endothelial-like tissue situated at the intersection of the cornea and the iris. The trabecular meshwork provides drainage for the aqueous humor. GO:0002931 response to ischemia biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002931 Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a inadequate blood supply. GO:0002932 tendon sheath development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002932 The process whose specific outcome is the progression of a tendon sheath over time, from its formation to the mature structure. A tendon sheath is a layer of membrane around a tendon. It permits the tendon to move. CHEBI:9440 tenuazonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_9440 CHEBI:26214 porphyrins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26214 CHEBI:26216 potassium atom biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_26216 CHEBI:41837 (4S,5S)-1,2-dithiane-4,5-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_41837 GO:0002937 tRNA 4-thiouridine biosynthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002937 The processes whereby a uridine residue in a tRNA is converted to 4-thiouridine. Typically 4-thiouridine is found at position 8, in many transfer RNAs. GO:0002938 tRNA guanine ribose methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002938 The process whereby a guanosine residue in a tRNA is methylated on the 2'-hydroxyl group of the ribose moiety. GO:0002939 tRNA N1-guanine methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002939 tRNA m1-guanine biosynthesis The process whereby a guanine in tRNA is methylated at position N1 of the guanine. GO:0002933 lipid hydroxylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002933 fatty acid hydroxylation The covalent attachment of a hydroxyl group to one or more fatty acids in a lipid. GO:0002934 desmosome organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002934 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm. GO:0002935 tRNA (adenine-C2-)-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0002935 Catalysis of the reaction: 2 S-adenosyl-L-methionine + adenine(37) in tRNA = S-adenosyl-L-homocysteine + 5'-deoxyadenosine + L-methionine + C2-methyladenine(37) in a tRNA. GO:0002936 bradykinin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002936 The chemical reactions and pathways resulting in the formation of the peptide hormone bradykinin. GO:0051874 sphinganine-1-phosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051874 dihydrosphingosine-1-phosphate catabolic process|dihydrosphingosine-1-phosphate catabolism The chemical reactions and pathways resulting in the breakdown of sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol. GO:0051875 pigment granule localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051875 pigment granule localisation Any process in which a pigment granule is transported to, and/or maintained in, a specific location within the cell. CHEBI:9493 tetrahymanol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_9493 GO:0051872 sphingosine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051872 (4E)-sphing-4-enine catabolism|sphing-4-enine catabolism|sphing-4-enine catabolic process|(4E)-sphing-4-enine catabolic process The chemical reactions and pathways resulting in the breakdown of sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues. CHEBI:145565 macrolide lactam biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145565 GO:0051873 killing by host of symbiont cells biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051873 disruption by host of symbiont cells Any process mediated by an organism that results in the death of cells in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:90790 18(R)-HETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90790 GO:0051878 lateral element assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051878 The cell cycle process in which lateral elements are formed. Axial elements form a proteinaceous core between the two sister chromatids of each chromosome; the two axial elements then connect along their entire lengths by fine fibers known as transverse filaments, forming the lateral elements. GO:0051879 Hsp90 protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051879 Hsp90 class protein binding|Hsp90 binding Interacting selectively and non-covalently with Hsp90 proteins, any of a group of heat shock proteins around 90kDa in size. GO:0051876 pigment granule dispersal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051876 The directed movement of pigment granules within a cell towards the cell periphery. GO:0051877 pigment granule aggregation in cell center biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051877 The directed movement of dispersed pigment granules towards the center of the cell. GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061200 clathrin sculpted gamma-aminobutyric acid transport vesicle|clathrin sculpted GABA transport vesicle A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing gamma-aminobutyric acid transport vesicle. GO:0036233 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0036233 GO:0061201 clathrin-sculpted gamma-aminobutyric acid transport vesicle lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061201 clathrin sculpted GABA transport vesicle lumen|clathrin sculpted gamma-aminobutyric acid transport vesicle lumen The volume enclosed by the membrane of the clathrin-sculpted gamma-aminobutyric acid transport vesicle. GO:0036234 deglucuronidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036234 The removal of glucuronic acid from a conjugated substrate. GO:0036235 acyl deglucuronidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036235 The removal of glucuronic acid from an acyl-glucuronide. GO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061202 clathrin sculpted GABA transport vesicle membrane|clathrin sculpted gamma-aminobutyric acid transport vesicle membrane The lipid bilayer surrounding a clathrin-sculpted gamma-aminobutyric acid transport vesicle. GO:0036236 acyl glucuronidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036236 The modification of an substrate by the conjugation of glucuronic acid to form an acyl-glucuronide (also called an acyl-glucuronoside). GO:0061203 striated muscle paramyosin thick filament assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061203 The aggregation, arrangement and bonding together of proteins to form the paramyosin-based thick filaments of myofibrils in striated muscle. CHEBI:90799 dipeptide zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90799 GO:0036237 acyl-glucuronidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036237 acyl-glucuronide deglucuronidation activity Catalysis of the reaction: an acyl-glucuronoside + H2O = an alcohol + D-glucuronate. GO:0061204 paramyosin filament assembly or disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061204 The formation or disassembly of a filament composed of paramyosin molecules. CHEBI:75150 3-dehydro-D-glucose-6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75150 GO:0036238 gallate dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036238 KEGG_REACTION:R09565|MetaCyc:GALLATE-DIOXYGENASE-RXN|EC:1.13.11.57|RHEA:28927 Catalysis of the reaction: gallate + O2 = (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate. GO:0061205 paramesonephric duct development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061205 Mullerian duct development The process whose specific outcome is the progression of the paramesonephric duct over time, from its formation to the mature structure. Mullerian ducts (or paramesonephric ducts) are paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, cervix, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin. GO:0061206 mesonephros morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061206 Wolffian body morphogenesis The process in which the anatomical structures of the mesonephros are generated and organized. GO:0036239 taxoid 7beta-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036239 MetaCyc:RXN-12885|EC:1.14.13.147|RHEA:31975|KEGG_REACTION:R09868 Catalysis of the reaction: taxusin + O2 + NADPH + H+ = 7beta-hydroxytaxusin + NADP+ + H2O. GO:0061207 mesonephric juxtaglomerulus cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061207 The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the mesonephros as it progresses from its formation to the mature state. CHEBI:90795 bacteriochlorophyllide a(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90795 GO:0061208 cell differentiation involved in mesonephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061208 The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephros as it progresses from its formation to the mature state. GO:0061209 cell proliferation involved in mesonephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061209 The multiplication or reproduction of cells, resulting in the expansion of the population in the mesonephros. CHEBI:75155 1-(alk-1-enyl)-2-arachidonoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75155 CHEBI:90796 D-erythrulose 4-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90796 CHEBI:90797 19-hydroxyprostaglandin H2(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90797 CHEBI:90798 L-erythrulose 4-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90798 CHEBI:75158 1-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75158 GO:0051870 methotrexate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051870 Interacting selectively and non-covalently with methotrexate, an antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of tetrahydrofolate reductase and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA. CHEBI:90791 3-(1-hydroxyethyl)bacteriochlorophyllide a(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90791 GO:0051871 dihydrofolic acid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051871 dihydrofolate binding|DHF binding Interacting selectively and non-covalently with dihydrofolic acid, a folic acid in which the bicyclic pteridine structure is in the dihydro, partially reduced form; they are intermediates in folate metabolism and are reduced to their tetrahydro, reduced forms. GO:0036230 granulocyte activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036230 The change in morphology and behavior of a granulocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. CHEBI:90792 3-(1-hydroxyethyl)chlorophyllide a(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90792 CHEBI:90793 prostaglandin H1(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90793 GO:0036231 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0036231 CHEBI:90794 3-acetylchlorophyllide a(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90794 GO:0036232 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0036232 GO:0051885 positive regulation of timing of anagen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051885 upregulation of anagen|stimulation of anagen|activation of anagen|up-regulation of anagen|positive regulation of anagen|up regulation of anagen Any process that activates or increases the frequency, rate or extent of timing of anagen, the growth phase of the hair cycle. GO:0051886 negative regulation of timing of anagen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051886 downregulation of anagen|inhibition of anagen|down regulation of anagen|negative regulation of anagen|down-regulation of anagen Any process that stops, prevents, or reduces the frequency, rate or extent of timing of anagen, the growth phase of the hair cycle. GO:0051883 killing of cells in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051883 killing of cells in other organism during symbiotic interaction Any process mediated by an organism that results in the death of cells in a second organism, where the two organisms are in a symbiotic interaction. GO:0051884 regulation of timing of anagen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051884 regulation of anagen Any process that modulates the frequency, rate or extent of timing of anagen, the growth phase of the hair cycle. CHEBI:145555 macropolylide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145555 GO:0051889 negative regulation of timing of exogen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051889 down-regulation of exogen|negative regulation of exogen|downregulation of exogen|inhibition of exogen|down regulation of exogen Any process that stops, prevents, or reduces the frequency, rate or extent of timing of exogen, the shedding phase of the hair cycle. CHEBI:145556 macrodiolide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145556 GO:0051887 regulation of timing of exogen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051887 regulation of exogen Any process that modulates the frequency, rate or extent of timing of exogen, the shedding phase of the hair cycle. GO:0051888 positive regulation of timing of exogen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051888 positive regulation of exogen|up regulation of exogen|upregulation of exogen|stimulation of exogen|activation of exogen|up-regulation of exogen Any process that activates or increases the frequency, rate or extent of timing of exogen, the shedding phase of the hair cycle. CHEBI:145559 macrotriolide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145559 CHEBI:145550 peregrinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_145550 GO:0036222 XTP diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036222 KEGG_REACTION:R02720|EC:3.6.1.66|MetaCyc:RXN0-5074|RHEA:28610|MetaCyc:RXN0-1603|Reactome:R-HSA-2509831 XTPase activity|hypoxanthine/xanthine dNTP pyrophosphatase|XTP pyrophosphohydrolase activity|XTP/dITP diphosphatase Catalysis of the reaction: XTP + H2O <=> H+ + XDP + monophosphate. GO:0036223 cellular response to adenine starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036223 cellular response to adenine deprivation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of adenine. GO:0036224 pairing center biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036224 homolog recognition region A special chromosome region located towards one end of a chromosome that contains dispersed copies of short, repetitive DNA sequences and functions as a cis-acting element essential for presynaptic homologous chromosome pairing and chromosome-nuclear envelope attachment. GO:0036225 cellular response to vitamin B1 starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036225 cellular response to vitamin B1 deprivation|cellular response to thiamin starvation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of vitamin B1 (also called thiamin and thiamine). CHEBI:75161 1-myristoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75161 GO:0036226 obsolete mitotic cell cycle arrest in response to glucose starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036226 cell cycle arrest in response to glucose starvation OBSOLETE. The process in which the mitotic cell cycle is halted during one of the normal phases (G1, S, G2, M) as a result of deprivation of glucose. GO:0036227 mitotic G2 cell cycle arrest in response to glucose starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036227 The process in which the mitotic cell cycle is halted during G2 phase as a result of deprivation of glucose. GO:0036228 protein localization to nuclear inner membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036228 protein targeting to nuclear inner membrane|protein targeting to INM A process in which a protein is transported to, or maintained in, a location within the nuclear inner membrane. CHEBI:75160 1-palmitoyl-2-lauroyl-sn-glycero-3-phospho-1D-myo-inositol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75160 GO:0036229 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0036229 CHEBI:90784 aurachin B(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90784 CHEBI:90785 4-hydroxy-2-methyl-3-oxo-[(2E,6E)-farnesyl]-3,4-dihydroquinoline-1-oxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90785 CHEBI:51177 antitussive biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51177 CHEBI:90786 2-methyl-1-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline-3,4-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90786 CHEBI:75163 1,2-dioleoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75163 CHEBI:75169 1-oleoyl-2-arachidonoyl-sn-glycerol-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75169 GO:0051881 regulation of mitochondrial membrane potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051881 Any process that modulates the establishment or extent of the mitochondrial membrane potential, the electric potential existing across the mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. GO:0051882 mitochondrial depolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051882 mitochondrion depolarization|mitochondria depolarization|mitochondrial depolarisation|mitochondrial membrane depolarization The process in which the potential difference across the mitochondrial membrane is reduced from its steady state level. CHEBI:90781 13-oxo-9Z,11E-ODE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90781 GO:0036220 ITP diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036220 KEGG_REACTION:R00720|MetaCyc:RXN0-6382|RHEA:29399|Reactome:R-HSA-2509827 inosine-5'-triphosphate pyrophosphohydrolase activity Catalysis of the reaction: ITP + H2O = IMP + diphosphate. CHEBI:90782 C-terminal proteinogenic amino-acid residue(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90782 CHEBI:90783 C-terminal S-(Gly-Gly)-L-Cys zwitterion residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90783 GO:0036221 UTP diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036221 KEGG_REACTION:R00662|RHEA:29395 uridine triphosphate pyrophosphohydrolase activity Catalysis of the reaction: UTP + H2O = UMP + diphosphate. GO:0051880 G-quadruplex DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051880 G-quartet DNA binding|G-quartet binding|tetraplex DNA binding|G-DNA binding|quadruplex DNA binding|G quartet DNA binding|G quadruplex DNA binding|G quartet binding Interacting selectively and non-covalently with G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures. G-quadruplex DNA can form under physiological conditions from some G-rich sequences, such as those found in telomeres, immunoglobulin switch regions, gene promoters, fragile X repeats, and the dimerization domain in the human immunodeficiency virus (HIV) genome. CHEBI:75168 1-oleoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75168 GO:0051896 regulation of protein kinase B signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051896 regulation of PKB signalling cascade|regulation of protein kinase B signalling cascade|regulation of AKT signalling cascade|regulation of protein kinase B signaling cascade|regulation of AKT signaling cascade|regulation of PKB signaling cascade Any process that modulates the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B. CHEBI:9470 tetracenomycin C biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_9470 GO:0051897 positive regulation of protein kinase B signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051897 positive regulation of PKB signaling cascade|upregulation of protein kinase B signaling cascade|positive regulation of AKT signaling cascade|stimulation of protein kinase B signaling cascade|activation of protein kinase B signaling cascade|positive regulation of protein kinase B signalling cascade|up-regulation of protein kinase B signaling cascade|up regulation of protein kinase B signaling cascade|positive regulation of AKT signalling cascade|positive regulation of PKB signalling cascade|positive regulation of protein kinase B signaling cascade Any process that activates or increases the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B. GO:0051894 positive regulation of focal adhesion assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051894 up regulation of focal adhesion formation|upregulation of focal adhesion formation|stimulation of focal adhesion formation|up-regulation of focal adhesion formation|activation of focal adhesion formation Any process that activates or increases the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions. GO:0051895 negative regulation of focal adhesion assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051895 downregulation of focal adhesion formation|down regulation of focal adhesion formation|inhibition of focal adhesion formation|down-regulation of focal adhesion formation Any process that stops, prevents, or reduces the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions. CHEBI:145544 S-nitrosoglutathione(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_145544 CHEBI:145545 nitrosothio compound biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_145545 GO:0051898 negative regulation of protein kinase B signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051898 negative regulation of PKB signaling cascade|negative regulation of AKT signaling cascade|negative regulation of protein kinase B signalling cascade|down-regulation of protein kinase B signaling cascade|negative regulation of AKT signalling cascade|negative regulation of PKB signalling cascade|negative regulation of protein kinase B signaling cascade|downregulation of protein kinase B signaling cascade|inhibition of protein kinase B signaling cascade|down regulation of protein kinase B signaling cascade Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B. GO:0051899 membrane depolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051899 The process in which membrane potential decreases with respect to its steady-state potential, usually from negative potential to a more positive potential. For example, the initial depolarization during the rising phase of an action potential is in the direction from the negative steady-state resting potential towards the positive membrane potential that will be the peak of the action potential. GO:0036219 GTP diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036219 RHEA:29391|KEGG_REACTION:R00426 GTP diphosphohydrolase activity|GTP diphosphohydrolase (diphosphate-forming); guanosine 5'-triphosphate pyrophosphohydrolase Catalysis of the reaction: GTP + H2O = GMP + diphosphate. GO:0061220 mesonephric macula densa development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061220 The process whose specific outcome is the progression of the mesonephric macula densa over time, from its formation to the mature structure. The mesonephric macula densa is an area of specialized cells in the distal tubule of the mesonephros that makes contact with the vascular pole of the glomerulus. GO:0061221 mesonephric mesenchyme morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061221 The process in which the anatomical structures of a mesonephric mesenchymal tissue are generated and organized. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros. GO:0036211 protein modification process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036211 protein modification The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification). GO:0061222 mesonephric mesenchymal cell proliferation involved in mesonephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061222 The multiplication or reproduction of cells, resulting in the expansion of a mesonephric mesenchymal cell population. GO:0061223 mesonephric mesenchymal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061223 The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the mesonephros as it progresses from its formation to the mature state. GO:0036212 contractile ring maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036212 The process in which the contractile ring is maintained, typically in response to an internal or external cue. GO:0061224 mesonephric glomerulus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061224 The progression of the mesonephric glomerulus over time from its initial formation until its mature state. The mesonephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or mesonephros. GO:0036213 contractile ring contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036213 The process of an actomyosin ring getting smaller in diameter. GO:0061225 mesonephric extraglomerular mesangial cell proliferation involved in mesonephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061225 mesonephric Goormaghtigh proliferation|mesonephric lacis cell proliferation The multiplication or reproduction of extraglomerular glomerular mesangium cells in the mesonephros by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa. GO:0036214 contractile ring localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036214 The process in which a contractile ring is assembled and/or maintained in a specific location. GO:0036215 response to stem cell factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036215 response to stem cell factor stimulus|response to KIT ligand|response to hematopoietic growth factor KL|response to SCF Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stem cell factor (SCF) stimulus. GO:0061226 proximal/distal pattern formation involved in mesonephric nephron development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061226 The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron in the mesonephros. The proximal/distal axis is defined by a line that runs from the glomerulus (proximal end) outward toward the mesonephric duct (distal end). CHEBI:75173 1-acyl-2-oleoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75173 GO:0036216 cellular response to stem cell factor stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036216 cellular response to KITLG|cellular response to SCF|cellular response to KIT ligand|cellular response to hematopoietic growth factor KL Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stem cell factor (SCF) stimulus. GO:0061227 pattern specification involved in mesonephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061227 mesonephros pattern formation|mesonephros pattern specification Any developmental process that results in the creation of defined areas or spaces within the mesonephros to which cells respond and eventually are instructed to differentiate. GO:0036217 dGTP diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036217 RHEA:28362|KEGG_REACTION:R01855 2'-deoxyguanosine 5'-triphosphate diphosphohydrolase Catalysis of the reaction: dGTP + H2O = dGMP + diphosphate. GO:0061228 mesonephric nephron morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061228 The process in which the anatomical structures of the mesonephric nephron are generated and organized. A mesonephric nephron is the functional unit of the mesonephros. GO:0036218 dTTP diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036218 RHEA:28534|MetaCyc:RXN0-5107|EC:3.6.1.9 Catalysis of the reaction: dTTP + H2O = dTMP + diphosphate. GO:0061229 mesonephric juxtaglomerulus cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061229 The process whose specific outcome is the progression of a mesonephric juxtaglomerulus cell over time, from its formation to the mature structure. GO:0051892 negative regulation of cardioblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051892 down regulation of cardioblast differentiation|downregulation of cardioblast differentiation|down-regulation of cardioblast differentiation|inhibition of cardioblast differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. GO:0051893 regulation of focal adhesion assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051893 regulation of adhesion plaque assembly Any process that modulates the frequency, rate or extent of focal adhesion formation, the establishment and maturation of focal adhesions. GO:0051890 regulation of cardioblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051890 Any process that modulates the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. GO:0051891 positive regulation of cardioblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051891 up regulation of cardioblast differentiation|activation of cardioblast differentiation|stimulation of cardioblast differentiation|up-regulation of cardioblast differentiation|upregulation of cardioblast differentiation Any process that activates or increases the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. GO:0036210 protein modification process in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036210 protein modification in other organism The covalent alteration performed by one organism of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) in another organism. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification). GO:0036208 obsolete negative regulation of histone gene expression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036208 down-regulation of histone gene expression|inhibition of histone gene expression|negative regulation of expression of histone-encoding gene|downregulation of histone gene expression OBSOLETE. Any process that decreases the frequency, rate or extent of expression of a histone-encoding gene. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. GO:0036209 9beta-pimara-7,15-diene oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036209 EC:1.14.14.111|RHEA:31951|KEGG_REACTION:R09865 Catalysis of the reaction: 9beta-pimara-7,15-diene + 3 O2 + 3 NADPH + 3 H+ = 9beta-pimara-7,15-dien-19-oate + 3 NADP+ + 4 H2O. This is a three-step reaction: (a) 9beta-pimara-7,15-diene + O2 + NADPH + H+ = 9beta-pimara-7,15-dien-19-ol + NADP+ + H2O, (b) 9beta-pimara-7,15-dien-19-ol + O2 + NADPH + H+ = 9neta-pimara-7,15-dien-19-al + NADP+ + 2 H2O, (c) 9beta-pimara-7,15-dien-19-al + O2 + NADPH + H+ = 9beta-pimara-7,15-dien-19-oate + NADP+ + H2O. GO:0061210 cell-cell signaling involved in mesonephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061210 cell-cell signalling involved in mesonephros development Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mesonephros over time, from its formation to the mature organ. GO:0061211 mesonephric collecting duct development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061211 The process whose specific outcome is the progression of a collecting duct in the mesonephros over time, from its formation to the mature structure. The collecting duct regulates water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder. GO:0036200 3-ketosteroid 9-alpha-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036200 EC:1.14.15.30|RHEA:32199|KEGG_REACTION:R09860 KshAB activity|3-ketosteroid 9alpha-hydroxylase activity Catalysis of the reaction: androsta-1,4-diene-3,17-dione + NADH + H+ + O2 = 9alpha-hydroxyandrosta-1,4-diene-3,17-dione + NAD+ + H2O. GO:0036201 ent-isokaurene C2-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036201 RHEA:56336|KEGG_REACTION:R09861|EC:1.14.14.76 Catalysis of the reaction: ent-isokaurene + O2 + NADPH + H+ = ent-2alpha-hydroxyisokaurene + H2O + NADP+. GO:0061212 mesonephric juxtaglomerular apparatus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061212 The process whose specific outcome is the progression of the juxtaglomerular apparatus in the mesonephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate. GO:0036202 ent-cassa-12,15-diene 11-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036202 RHEA:31967|KEGG_REACTION:R09866|EC:1.14.14.112 ent-cassadiene C11alpha-hydroxylase activity Catalysis of the reaction: ent-cassa-12,15-diene + O2 + NADPH + H+ = ent-11beta-hydroxycassa-12,15-diene + NADP+ + H2O. GO:0061213 positive regulation of mesonephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061213 Any process that increases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. GO:0061214 mesonephric smooth muscle tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061214 The process whose specific outcome is the progression of smooth muscle in the mesonephros over time, from its formation to the mature structure. GO:0036203 taxoid 14-beta-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036203 RHEA:31971|KEGG_REACTION:R09867|EC:1.14.13.146 Catalysis of the reaction: 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + O2 + NADPH + H+ = 10beta,14beta-dihydroxytaxa-4(20),11-dien-5alpha-yl acetate + NADP+ + H2O. GO:0036204 abieta-7,13-dien-18-ol hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036204 EC:1.14.14.145|KEGG_REACTION:R06354|RHEA:26221|MetaCyc:RXN-12799 Catalysis of the reaction: abieta-7,13-dien-18-ol + NADPH + H+ + O2 = abieta-7,13-dien-18-al + NADP+ + 2 H2O. This is a two step reaction. The first step is: abieta-7,13-dien-18-ol + NADPH + H+ + O2 = abieta-7,13-dien-18,18-diol + + NADP+ + H2O. The second step is a spontaneous reaction: abieta-7,13-dien-18,18-diol = abieta-7,13-dien-18-al + H2O. GO:0061215 mesonephric nephron development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061215 The process whose specific outcome is the progression of a nephron in the mesonephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney. GO:0061216 regulation of transcription from RNA polymerase II promoter involved in mesonephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061216 Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the mesonephros progressing from its initial formation to the mature state. GO:0036205 histone catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036205 histone protein catabolic process The chemical reactions and pathways resulting in the breakdown of a histone protein by individual cells. GO:0061217 regulation of mesonephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061217 Any process that modulates the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine. GO:0036206 obsolete regulation of histone gene expression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036206 regulation of expression of histone-encoding gene OBSOLETE. Any process that modulates the frequency, rate or extent of expression of a histone-encoding gene. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. GO:0061218 negative regulation of mesonephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061218 Any process that decreases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. GO:0036207 obsolete positive regulation of histone gene expression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036207 up-regulation of histone gene expression|positive regulation of expression of histone-encoding gene|upregulation of histone gene expression|activation of histone gene expression OBSOLETE. Any process that increases the frequency, rate or extent of expression of a histone-encoding gene. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. GO:0061219 mesonephric mesenchyme development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061219 The biological process whose specific outcome is the progression of a mesonephric mesenchyme from an initial condition to its mature state. This process begins with the formation of mesonephric mesenchyme and ends with the mature structure. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros. CHEBI:145538 N-acylethanolamine phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145538 CHEBI:566274 malonaldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_566274 CHEBI:51151 dipolar compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51151 CHEBI:75189 N-acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75189 CHEBI:51149 xanthones biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51149 CHEBI:26187 polyprenyl phospho carbohydrate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26187 CHEBI:26188 polyketide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26188 GO:0061240 mesonephric nephron tubule morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061240 The process in which the anatomical structures of a mesonephric nephron tubule are generated and organized. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros. GO:0061241 mesonephric nephron epithelium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061241 The process whose specific outcome is the progression of the mesonephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros. GO:0061242 mesonephric nephron tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061242 The progression of a mesonephric nephron tubule over time, from its initial formation to the mature structure. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros. CHEBI:26185 polyprenyl glycosyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26185 GO:0061243 mesonephric renal vesicle morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061243 The process in which the anatomical structures of the mesonephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the mesonephric nephron epithelium, and is formed by the condensation of mesenchymal cells. CHEBI:26186 polyprenyl phospho oligosaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26186 GO:0061244 mesonephric S-shaped body morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061244 The process in which the mesonephric S-shaped body is generated and organized. The mesonephric S-shaped body is the successor of the mesonephric comma-shaped body that contributes to the morphogenesis of a nephron in the mesonephros. CHEBI:75190 EC 5.4.3.2 (lysine 2,3-aminomutase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75190 GO:0061245 establishment or maintenance of bipolar cell polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061245 Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns. CHEBI:26191 polyol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26191 CHEBI:75191 N-acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-6-O-phosphonato-alpha-D-mannosyl group(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75191 GO:0061246 establishment or maintenance of bipolar cell polarity regulating cell shape biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061246 Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns that regulates the shaping of a cell. GO:0061247 mesonephric glomerular mesangium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061247 The process whose specific outcome is the progression of the mesonephric glomerular mesangium over time, from its formation to the mature structure. The mesonephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the mesonephros, which helps to support the capillary loops in a renal glomerulus. GO:0061248 mesonephric glomerulus vasculature morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061248 The process in which the anatomical structures of the mesonephric glomerulus vasculature are generated and organized. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus. CHEBI:75194 phosphatidylinositol 36:4(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75194 GO:0061249 mesonephric glomerular capillary formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061249 The process that gives rise to a mesonephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts. CHEBI:75195 phosphatidylglycerol 32:0(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75195 CHEBI:51143 nitrogen molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51143 CHEBI:75199 phosphatidylglycerol 36:1(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75199 CHEBI:51144 nitrogen group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51144 CHEBI:51145 secondary amino group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51145 CHEBI:75196 phosphatidylglycerol 32:1(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75196 CHEBI:51146 tertiary amino group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_51146 CHEBI:51142 amino groups biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51142 NCBITaxon:241407 Saccharomycetales incertae sedis organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_241407 CHEBI:26199 polyprenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_26199 GO:0061230 mesonephric juxtaglomerulus cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061230 The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric juxtaglomerulus cell. CHEBI:26195 polyphenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26195 GO:0061231 mesonephric glomerulus vasculature development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061231 The biological process whose specific outcome is the progression of a mesonephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the mesonephric glomerulus vasculature and ends with the mature structure. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus. CHEBI:26196 polyphenylpropanoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26196 GO:0061232 mesonephric glomerular epithelium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061232 The process whose specific outcome is the progression of the mesonephric glomerular epithelium over time, from its formation to the mature structure. The mesonephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the mesonephros. The mesonephric glomerular epithelium consists of both parietal and visceral epithelium. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros. GO:0061233 mesonephric glomerular basement membrane development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061233 The process whose specific outcome is the progression of the mesonephric glomerular basement membrane over time, from its formation to the mature structure. The mesonephric glomerular basement membrane is the basal laminal portion of the mesonephric glomerulus which performs the actual filtration. GO:0061234 mesonephric glomerulus morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061234 The process in which the anatomical structures of the mesonephric glomerulus are generated and organized. The mesonephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate mesonephros. GO:0061235 mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061235 The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells. GO:0061236 mesonephric comma-shaped body morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061236 The process in which the mesonephric comma-shaped body is generated and organized. The mesonephric comma-shaped body is the precursor structure to the mesonephric S-shaped body that contributes to the morphogenesis of a nephron in the mesonephros. GO:0061237 convergent extension involved in mesonephric nephron morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061237 The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron in the mesonephros. GO:0061238 establishment of planar polarity involved in mesonephric nephron morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061238 establishment of planar cell polarity involved in mesonephric nephron morphogenesis Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron in the mesonephros. GO:0061239 mesenchymal stem cell differentiation involved in mesonephric nephron morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061239 The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephronin the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells. CHEBI:51132 nitroarene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51132 GO:0002885 positive regulation of hypersensitivity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002885 up regulation of hypersensitivity|upregulation of hypersensitivity|stimulation of hypersensitivity|up-regulation of hypersensitivity|activation of hypersensitivity Any process that activates or increases the frequency, rate, or extent of hypersensitivity. CHEBI:51129 nitrohydrocarbon biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51129 GO:0002886 regulation of myeloid leukocyte mediated immunity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002886 Any process that modulates the frequency, rate, or extent of myeloid leukocyte mediated immunity. GO:0002887 negative regulation of myeloid leukocyte mediated immunity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002887 down regulation of myeloid leukocyte mediated immunity|downregulation of myeloid leukocyte mediated immunity|down-regulation of myeloid leukocyte mediated immunity|inhibition of myeloid leukocyte mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte mediated immunity. GO:0002888 positive regulation of myeloid leukocyte mediated immunity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002888 upregulation of myeloid leukocyte mediated immunity|up regulation of myeloid leukocyte mediated immunity|activation of myeloid leukocyte mediated immunity|stimulation of myeloid leukocyte mediated immunity|up-regulation of myeloid leukocyte mediated immunity Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte mediated immunity. GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002881 down regulation of chronic inflammatory response to non-antigenic stimulus|downregulation of chronic inflammatory response to non-antigenic stimulus|down-regulation of chronic inflammatory response to non-antigenic stimulus|inhibition of chronic inflammatory response to non-antigenic stimulus Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus. GO:0002882 positive regulation of chronic inflammatory response to non-antigenic stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002882 upregulation of chronic inflammatory response to non-antigenic stimulus|up regulation of chronic inflammatory response to non-antigenic stimulus|activation of chronic inflammatory response to non-antigenic stimulus|stimulation of chronic inflammatory response to non-antigenic stimulus|up-regulation of chronic inflammatory response to non-antigenic stimulus Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus. GO:0002883 regulation of hypersensitivity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002883 Any process that modulates the frequency, rate, or extent of hypersensitivity. GO:0002884 negative regulation of hypersensitivity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002884 downregulation of hypersensitivity|down regulation of hypersensitivity|inhibition of hypersensitivity|down-regulation of hypersensitivity Any process that stops, prevents, or reduces the frequency, rate, or extent of hypersensitivity. GO:0061260 mesonephric mesangial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061260 The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the mesonephros as it progresses from its formation to the mature state. CHEBI:26167 polar amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26167 GO:0061261 mesenchymal to epithelial transition involved in mesonephros morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061261 mesonephric mesenchyme to epithelial transition A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephros. GO:0002880 regulation of chronic inflammatory response to non-antigenic stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002880 Any process that modulates the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus. GO:0061262 mesonephric renal vesicle formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061262 mesonephros formation The developmental process pertaining to the initial formation of the mesonephros. GO:0061263 mesonephric glomerular mesangial cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061263 The process whose specific outcome is the progression of a glomerular mesangial cell in the mesonephros over time, from its formation to the mature structure. GO:0061264 mesonephric glomerular mesangial cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061264 The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular mesangial cell. GO:0061265 mesonephric nephron tubule epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061265 The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephric nephron tubule as it progresses from its formation to the mature state. GO:0061266 mesonephric interstitial fibroblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061266 mesonephros interstitial cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblasts of the mesonephros as it progresses from its formation to the mature state. GO:0061267 mesonephric interstitial fibroblast development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061267 mesonephros interstitial cell development The process whose specific outcome is the progression of a mesonephric interstitial fibroblast over time, from its formation to the mature structure. GO:0061268 mesonephric interstitial fibroblast fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061268 The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric interstitial fibroblast. GO:0061269 mesonephric glomerular mesangial cell proliferation involved in mesonephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061269 The multiplication or reproduction of glomerular mesangial cells in the mesonephros, resulting in the expansion of the population. CHEBI:51121 fluorescent dye biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51121 GO:0002889 regulation of immunoglobulin mediated immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002889 Any process that modulates the frequency, rate, or extent of an immunoglobulin mediated immune response. CHEBI:51120 ortho- and peri-fused tricyclic hydrocarbon biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51120 GO:0002896 negative regulation of central B cell tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002896 down-regulation of central B cell tolerance induction|downregulation of central B cell tolerance induction|down regulation of central B cell tolerance induction|inhibition of central B cell tolerance induction Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell tolerance induction. GO:0002897 positive regulation of central B cell tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002897 up regulation of central B cell tolerance induction|upregulation of central B cell tolerance induction|stimulation of central B cell tolerance induction|up-regulation of central B cell tolerance induction|activation of central B cell tolerance induction Any process that activates or increases the frequency, rate, or extent of central B cell tolerance induction. CHEBI:51119 tricyclic hydrocarbon biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51119 GO:0002898 regulation of central B cell deletion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002898 Any process that modulates the frequency, rate, or extent of central B cell deletion. GO:0002899 negative regulation of central B cell deletion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002899 down regulation of central B cell deletion|downregulation of central B cell deletion|down-regulation of central B cell deletion|inhibition of central B cell deletion Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell deletion. GO:0002892 regulation of type II hypersensitivity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002892 Any process that modulates the frequency, rate, or extent of type II hypersensitivity. GO:0002893 negative regulation of type II hypersensitivity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002893 down-regulation of type II hypersensitivity|downregulation of type II hypersensitivity|down regulation of type II hypersensitivity|inhibition of type II hypersensitivity Any process that stops, prevents, or reduces the frequency, rate, or extent of type II hypersensitivity. GO:0002894 positive regulation of type II hypersensitivity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002894 stimulation of type II hypersensitivity|activation of type II hypersensitivity|up-regulation of type II hypersensitivity|up regulation of type II hypersensitivity|upregulation of type II hypersensitivity Any process that activates or increases the frequency, rate, or extent of type II hypersensitivity. GO:0002895 regulation of central B cell tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002895 Any process that modulates the frequency, rate, or extent of central B cell tolerance induction. CHEBI:26177 polyene antibiotic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26177 GO:0002890 negative regulation of immunoglobulin mediated immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002890 downregulation of immunoglobulin mediated immune response|down-regulation of immunoglobulin mediated immune response|inhibition of immunoglobulin mediated immune response|down regulation of immunoglobulin mediated immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of an immunoglobulin mediated immune response. CHEBI:26178 polyester macromolecule biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26178 GO:0002891 positive regulation of immunoglobulin mediated immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002891 up regulation of immunoglobulin mediated immune response|activation of immunoglobulin mediated immune response|stimulation of immunoglobulin mediated immune response|up-regulation of immunoglobulin mediated immune response|upregulation of immunoglobulin mediated immune response Any process that activates or increases the frequency, rate, or extent of an immunoglobulin mediated immune response. GO:0061250 mesonephric glomerular epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061250 The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells. CHEBI:26179 polyether antibiotic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26179 GO:0061251 mesonephric glomerular epithelial cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061251 The process whose specific outcome is the progression of a mesonephric glomerular epithelial cell over time, from its formation to the mature structure. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells. CHEBI:26172 poly(ribitol phosphate)s biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26172 GO:0061252 mesonephric glomerular epithelial cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061252 The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells. CHEBI:26174 poly(N-acetyllactosamine) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_26174 GO:0061253 mesonephric glomerular parietal epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061253 The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular parietal epithelial cell. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. GO:0061254 mesonephric glomerular parietal epithelial cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061254 The process whose specific outcome is the progression of a mesonephric glomerular parietal epithelial cell over time, from its formation to the mature structure. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. GO:0061255 mesonephric glomerular parietal epithelial cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061255 The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular parietal epithelial cell. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes. GO:0061256 mesonephric glomerular visceral epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061256 The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros. GO:0061257 mesonephric glomerular visceral epithelial cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061257 The process whose specific outcome is the progression of a mesonephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros. GO:0061258 mesonephric glomerular visceral epithelial cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061258 The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros. GO:0061259 mesonephric glomerular mesangial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061259 The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the mesonephros as it progresses from its formation to the mature state. CHEBI:90708 retinoic acid receptor modulator biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90708 CHEBI:90709 nuclear receptor modulator biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90709 CHEBI:90715 5,20-DiHETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90715 CHEBI:90716 8-HETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90716 CHEBI:90717 8,20-DiHETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90717 CHEBI:90718 12-HETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90718 CHEBI:90711 20-hydroxylipoxin B4(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90711 CHEBI:90710 receptor modulator biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90710 GO:0051801 cytolysis in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051801 cytolysis of cells in other organism involved in symbiotic interaction|cytolysis of cells in other organism during symbiotic interaction The killing by an organism of a cell in a second organism by means of the rupture of cell membranes and the loss of cytoplasm, where the two organisms are in a symbiotic interaction. GO:0051802 regulation of cytolysis in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051802 regulation of cytolysis of cells in other organism during symbiotic interaction|regulation of cytolysis of cells in other organism involved in symbiotic interaction Any process in which an organism modulates the frequency, rate or extent of the cytolysis by that organism of cells in a second organism, where the two organisms are in a symbiotic interaction. GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051800 Reactome:R-HSA-1676149|Reactome:R-HSA-1676204 PTEN activity Catalysis of the reaction: phosphatidylinositol-3,4-bisphosphate + H2O = phosphatidylinositol-4-phosphate + phosphate. GO:0051805 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051805 GO:0051806 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051806 GO:0051803 negative regulation of cytolysis in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051803 down-regulation of cytolysis of cells in other organism during symbiotic interaction|inhibition of cytolysis of cells in other organism during symbiotic interaction|negative regulation of cytolysis of cells in other organism involved in symbiotic interaction|negative regulation of cytolysis of cells in other organism during symbiotic interaction|down regulation of cytolysis of cells in other organism during symbiotic interaction|downregulation of cytolysis of cells in other organism during symbiotic interaction Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of cytolysis by that organism of cells in a second organism, where the two organisms are in a symbiotic interaction. PR:000013526 peptide YY biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000013526 peptide tyrosine tyrosine|PYY|PYY-I A protein that is a translation product of the human PYY gene or a 1:1 ortholog thereof. GO:0051804 positive regulation of cytolysis in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051804 up-regulation of cytolysis of cells in other organism during symbiotic interaction|positive regulation of cytolysis of cells in other organism during symbiotic interaction|upregulation of cytolysis of cells in other organism during symbiotic interaction|positive regulation of cytolysis of cells in other organism involved in symbiotic interaction|up regulation of cytolysis of cells in other organism during symbiotic interaction|activation of cytolysis of cells in other organism during symbiotic interaction|stimulation of cytolysis of cells in other organism during symbiotic interaction Any process in which an organism activates or increases the frequency, rate or extent of cytolysis by that organism of cells in a second organism, where the two organisms are in a symbiotic interaction. GO:0051809 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051809 GO:0051807 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051807 GO:0051808 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051808 CHEBI:90707 20-hydroxylipoxin A4(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90707 CHEBI:89719 propyl butyrate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_89719 CHEBI:65768 (9Z,12Z,15Z)-octadeca-9,12,15-trien-6-ynoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65768 GO:0051812 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051812 GO:0051813 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051813 GO:0051810 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051810 GO:0051811 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051811 GO:0051816 acquisition of nutrients from other organism during symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051816 The production of structures and/or molecules in an organism that are required for the acquisition and/or utilization of nutrients obtained from a second organism, where the two organisms are in a symbiotic interaction. GO:0051817 modulation of process of other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051817 modulation of morphology or physiology of other organism during symbiotic interaction|regulation of physiological process in other organism during symbiotic interaction|regulation of physiology of other organism during symbiotic interaction|modification of morphology or physiology of other organism during symbiotic interaction|modulation of biological process of other organism involved in symbiotic interaction|regulation of morphology or physiology of other organism during symbiotic interaction|modification of morphology or physiology of other organism involved in symbiotic interaction|regulation of morphology of other organism during symbiotic interaction The process in which an organism effects a change in the structure or processes of a second organism, where the two organisms are in a symbiotic interaction. GO:0051814 obsolete movement in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051814 movement within other organism during symbiotic interaction|movement in other organism during symbiotic interaction OBSOLETE. The process in which an organism or its progeny spreads from one location to another within a second organism, where the two organisms are in a symbiotic interaction. GO:0051815 obsolete migration in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051815 migration within other organism during symbiotic interaction|migration in other organism during symbiotic interaction OBSOLETE. The directional movement of an organism from one place to another within a second organism, where the two organisms are in a symbiotic interaction. GO:0051818 disruption of cells of other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051818 disruption of cells of other organism during symbiotic interaction A process in which an organism has a negative effect on the functioning of the second organism's cells, where the two organisms are in a symbiotic interaction. GO:0051819 induction by symbiont of tumor or growth in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051819 induction by symbiont of nodulation, tumor or growth in host|induction by symbiont in host of tumor, nodule, or growth containing transformed cells|induction of tumor, nodule, or growth containing transformed cells in other organism during symbiotic interaction|induction of tumor, nodule, or growth in other organism involved in symbiotic interaction|induction by symbiont in host of tumor, nodule, or growth|induction of tumor, nodule, or growth in other organism during symbiotic interaction|induction of tumor, nodule, or growth containing transformed cells in other organism involved in symbiotic interaction The process in which a symbiont causes the formation of a mass of cells in a host organism. While these growths are often called nodules, they are not formed as nitrogen-fixing structures, but rather to provide an environment for the symbiont to grow. In this sense they are parasitic structures rather than mutualistic. GO:0036299 non-recombinational interstrand cross-link repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036299 recombination-independent ICL repair|recombination-independent interstrand cross-link repair Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA by a mechanism that does not involve homologous DNA recombination. CHEBI:90737 5-HEPE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90737 CHEBI:90736 very long-chain acyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90736 GO:0036291 protein cis-autophosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036291 cis-autophosphorylation The phosphorylation by a protein of one or more of its own amino acid residues. GO:0036292 DNA rewinding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036292 RPA-dependent DNA rewinding|single-stranded DNA bubble rewinding|DNA annealing The process in which interchain hydrogen bonds between two single-stranded DNA (ssDNA) are reformed to regenerate double-stranded DNA (dsDNA). ssDNA is often bound and stabilized by proteins such as replication protein A (RPA) to form ssDNA bubbles. The bubbles can be rewound by ATP-dependent motors to reform base pairs between strands and thus dsDNA. GO:0036293 response to decreased oxygen levels biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036293 response to lowered oxygen levels Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen. GO:0036294 cellular response to decreased oxygen levels biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036294 cellular response to lowered oxygen levels Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen. CHEBI:90732 20-hydroxy-6-trans-leukotriene B4(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90732 GO:0036295 cellular response to increased oxygen levels biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036295 cellular response to raised oxygen levels Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting an increase in the level of oxygen. GO:0036296 response to increased oxygen levels biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036296 response to raised oxygen levels Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting an increase in the level of oxygen. GO:0036297 interstrand cross-link repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036297 ICL repair Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA. DNA interstrand crosslinks occur when both strands of duplex DNA are covalently tethered together (e.g. by an exogenous or endogenous agent), thus preventing the strand unwinding necessary for essential DNA functions such as transcription and replication. GO:0036298 recombinational interstrand cross-link repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036298 recombination-dependent interstrand cross-link repair Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA by a mechanism that involves the exchange, reciprocal or nonreciprocal, of genetic material between the broken DNA molecule and a homologous region of DNA. GO:0051820 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051820 CHEBI:75105 nonadecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75105 CHEBI:75106 1-oleoyl-2-palmitoyl-sn-glycero-3-phospho-L-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75106 GO:0051823 regulation of synapse structural plasticity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051823 regulation of synaptic structural plasticity Any process that modulates the frequency, rate or extent of synapse structural plasticity. Synapse structural plasticity is a type of cytoskeletal remodeling; this remodeling is induced by stimuli that can lead to long term potentiation and it can be activity-dependent or -independent. Examples of cytoskeletal changes include the formation of new spines and increase in spine size; this can be accompanied by the insertion of greater numbers of glutamate (or other neurotransmitter) receptors into the post-synaptic membrane. GO:0051824 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051824 GO:0051821 obsolete dissemination or transmission of organism from other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051821 dissemination or transmission of organism from other organism during symbiotic interaction OBSOLETE. The movement of an organism from a second organism to another place in the environment, where the two organisms are in a symbiotic interaction. The first organism may also move to a different organism. CHEBI:75109 1-acyl-2-oleoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75109 GO:0036290 protein trans-autophosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036290 trans-autophosphorylation The phosphorylation by a protein of a residue on an identical protein. For example, phosphorylation by the other kinase within a homodimer. GO:0051822 obsolete dissemination or transmission of organism from other organism by vector involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051822 dissemination or transmission of organism from other organism by vector during symbiotic interaction OBSOLETE. The movement of an organism from a second organism to another place in the environment by means of a vector, where the two organisms are in a symbiotic interaction. The first organism may also move to a different organism, and the vector organism is often an insect or an animal. GO:0051827 obsolete growth or development on or near surface of other organism during symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051827 growth or development on or near surface of other organism during symbiotic interaction OBSOLETE. The increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring on or near the exterior of a second organism, where the two organisms are in a symbiotic interaction. GO:0051828 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051828 GO:0051825 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051825 GO:0051826 negative regulation of synapse structural plasticity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051826 inhibition of synapse structural plasticity|down regulation of synapse structural plasticity|downregulation of synapse structural plasticity|down-regulation of synapse structural plasticity Any process that stops, prevents, or reduces the frequency, rate or extent of synapse structural plasticity. GO:0120006 regulation of glutamatergic neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120006 Any process that modulates the frequency, rate or extent of glutamatergic neuron differentiation. CHEBI:90719 12,20-DiHETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90719 GO:0120007 negative regulation of glutamatergic neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120007 Any process that stops, prevents or reduces the frequency, rate or extent of glutamatergic neuron differentiation. GO:0120008 positive regulation of glutamatergic neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120008 Any process that activates or increases the frequency, rate or extent of glutamatergic neuron differentiation. GO:0051829 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051829 GO:0120009 intermembrane lipid transfer biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120009 The transport of lipids between membranes in which a lipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs). GO:0120002 fusiform vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120002 A cytoplasmic vesicle which contains two urothelial plaques and can deliver these plaques to the apical plasma membrane of urothelial superficial (umbrella) cells. It can also be formed by endocytosis of apical plasma membrane during contractions of the urinary bladder. GO:0036288 response to ximelagatran biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0036288 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ximelagatran stimulus. CHEBI:90726 3-oxoacyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90726 GO:0120003 hinge region between urothelial plaques of apical plasma membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120003 A narrow rim of non-thickened membrane in between urothelial plaques in apical plasma membrane. GO:0036289 peptidyl-serine autophosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036289 serine autophosphorylation The phosphorylation by a protein of one or more of its own serine amino acid residues, or a serine residue on an identical protein. CHEBI:90722 20-hydroxy-20-oxoleukotriene B4(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90722 CHEBI:90723 6-trans-leukotriene B4(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90723 GO:0120001 apical plasma membrane urothelial plaque biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120001 asymmetric unit membrane|AUM A scallop-shaped plaque, also referred to as an asymmetric unit membrane (AUM), found in the apical plasma membrane of urothelial superficial (umbrella) cells which form a a barrier to the passage of water and soluble toxic compounds found in urine. The plaques are thickened regions of membrane composed of uroplakin transmembrane proteins which form a crystalline array. CHEBI:90725 very long-chain 3-oxoacyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90725 GO:0036280 cellular response to L-canavanine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036280 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-canavanine stimulus. L-canavanine is L-homoserine substituted at oxygen with a guanidino (carbamimidamido) group. GO:0036281 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0036281 GO:0036282 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0036282 CHEBI:90720 20-oxoleukotriene B4(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90720 GO:0036283 obsolete positive regulation of transcription factor import into nucleus in response to oxidative stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036283 positive regulation of transcription factor import into nucleus in response to hydrogen peroxide OBSOLETE. Any process that activates or increases the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus under conditions of oxidative stress. GO:0036284 tubulobulbar complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036284 TBC Actin-based structures involved in establishing close contact between Sertoli-Sertoli cells or Sertoli-spermatids in the seminiferous tubules of the testes. CHEBI:75103 1-oleoyl-2-stearoyl-sn-glycero-3-phospho-L-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75103 GO:0036285 SAGA complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036285 SAGA complex formation The aggregation, arrangement and bonding together of a set of components to form a SAGA complex, a SAGA-type histone acetyltransferase complex that contains Spt8 (in budding yeast) or a homolog thereof. CHEBI:75104 1-oleoyl-2-nonadecanoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75104 CHEBI:75101 1-oleoyl-2-palmitoleoyl-sn-glycero-3-phospho-L-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75101 GO:0036286 eisosome filament biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036286 linear eisosome A filamentous cortical structure formed, in S. pombe, by the eisosome component Pil1. GO:0036287 response to iloperidone biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0036287 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iloperidone stimulus. GO:0051830 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051830 CHEBI:75118 1-oleoyl-2-arachidonoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75118 GO:0051831 obsolete growth or development in other organism during symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051831 growth or development within other organism during symbiotic interaction|growth or development in other organism during symbiotic interaction|invasive growth OBSOLETE. The increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring within the cells or tissues of a second organism, where the two organisms are in a symbiotic interaction. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down the tissue of the second organism. CHEBI:75116 1-acyl-2-oleoyl-sn-glycero-3-phospho-1D-myo-inositol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75116 GO:0051834 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051834 GO:0051835 positive regulation of synapse structural plasticity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051835 up regulation of synapse structural plasticity|activation of synapse structural plasticity|stimulation of synapse structural plasticity|up-regulation of synapse structural plasticity|upregulation of synapse structural plasticity Any process that activates, maintains or increases the frequency, rate or extent of synaptic structural plasticity. GO:0051832 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051832 GO:0051833 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051833 GO:0051838 cytolysis by host of symbiont cells biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051838 The killing by an organism of a cell in its symbiont organism by means of the rupture of cell membranes and the loss of cytoplasm. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0051839 regulation by host of cytolysis of symbiont cells biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051839 Any process in which an organism modulates the frequency, rate or extent of the cytolysis by that organism of cells in its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0051836 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051836 GO:0051837 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051837 GO:0036277 response to anticonvulsant biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0036277 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anticonvulsant stimulus, a drug used to prevent seizures or reduce their severity. GO:0036278 positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036278 Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a deprivation of nitrogen. GO:0036279 positive regulation of protein export from nucleus in response to glucose starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036279 Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm in response to deprivation of glucose. CHEBI:75110 1-acyl-2-linoleoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75110 GO:0036270 response to diuretic biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0036270 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diuretic stimulus. A diuretic is an agent that promotes the excretion of urine through its effects on kidney function. CHEBI:75111 1-acyl-sn-glycero-3-phosphoglycerol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75111 GO:0036271 response to methylphenidate biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0036271 response to MPD|response to ritalin|response to MPH Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylphenidate stimulus. GO:0036272 response to gemcitabine biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0036272 response to 2'-deoxy-2',2'-difluorocytidine|response to 2',2'-difluorodeoxycytidine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gemcitabine stimulus. Gemcitabine is a 2'-deoxycytidine having geminal fluoro substituents in the 2'-position, and is used as a drug in the treatment of various carcinomas. GO:0036273 response to statin biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0036273 response to HMG-CoA reductase inhibitor|response to hydroxymethylglutaryl-CoA reductase inhibitor Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a statin stimulus. Statins are organooxygen compounds whose structure is related to compactin (mevastatin) and which may be used as an anticholesteremic drug due its EC:1.1.1.34/EC:1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitory properties. GO:0036274 response to lapatinib biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0036274 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lapatinib stimulus. GO:0036275 response to 5-fluorouracil biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0036275 response to fluorouracil|response to 5-fluoropyrimidine-2,4(1H,3H)-dione Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 5-fluorouracil stimulus. CHEBI:75112 1-acyl-2-arachidonoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75112 GO:0036276 response to antidepressant biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0036276 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antidepressant stimulus, a mood-stimulating drug. GO:0051841 positive regulation by host of cytolysis of symbiont cells biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051841 up-regulation by host of cytolysis of symbiont cells|upregulation by host of cytolysis of symbiont cells|up regulation by host of cytolysis of symbiont cells|activation by host of cytolysis of symbiont cells|stimulation by host of cytolysis of symbiont cells Any process in which an organism activates or increases the frequency, rate or extent of cytolysis by that organism of cells in its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0051842 obsolete evasion or tolerance of symbiont immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051842 immune evasion|evasion or tolerance of symbiont immune response OBSOLETE. Any process, either active or passive, by which an organism avoids the effects of the symbiont organism's immune response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:75127 alpha-N-acetylneuraminyl-(2->3)-D-galactosyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75127 GO:0051840 negative regulation by host of cytolysis of symbiont cells biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051840 down-regulation by host of cytolysis of symbiont cells|inhibition by host of cytolysis of symbiont cells|down regulation by host of cytolysis of symbiont cells|downregulation by host of cytolysis of symbiont cells Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of cytolysis by that organism of cells in its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0051845 obsolete passive evasion of symbiont immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051845 passive evasion of symbiont immune response|passive immune evasion OBSOLETE. Any mechanism of immune avoidance that does not directly interfere with the symbiont immune system. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0051846 obsolete active evasion of symbiont immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051846 active evasion of symbiont immune response|active immune evasion OBSOLETE. Any mechanism of immune avoidance that directly affects the symbiont immune system, e.g. blocking any stage in symbiont MHC class I and II presentation. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0051843 obsolete evasion or tolerance of symbiont defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051843 evasion or tolerance of symbiont defense response|evasion of symbiont defence response OBSOLETE. Any process, either active or passive, by which an organism avoids or tolerates the effects of a symbiont organism's defense response. The symbiont defense response is mounted by the symbiont in response to the presence of the organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0051844 translocation of peptides or proteins into symbiont biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051844 transport of peptides or proteins into symbiont The directed movement of peptides or proteins produced by an organism to a location inside the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0051849 obsolete active evasion of symbiont immune response via regulation of symbiont antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051849 active immune evasion via regulation of symbiont antigen processing or presentation|active evasion of symbiont immune response via regulation of symbiont antigen processing and presentation|active immune evasion via modulation of symbiont antigen processing/presentation|active evasion of symbiont immune response via regulation of symbiont antigen processing and presentation pathway|active immune evasion via modulation of symbiont antigen processing and presentation OBSOLETE. Any mechanism of active immune avoidance which works by regulating the symbiont's antigen processing or presentation pathways, e.g. by blocking any stage in MHC class II presentation. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0051847 obsolete active evasion of symbiont immune response via regulation of symbiont complement system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051847 active immune evasion via regulation of symbiont complement system|active immune evasion via modulation of symbiont complement system|active evasion of symbiont immune response via regulation of symbiont complement system OBSOLETE. Any mechanism of active immune avoidance which works by regulating the symbiont complement system, e.g. by possessing complement receptors which mediate attachment to, then infection of, symbiont macrophages, which are eventually destroyed. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0051848 obsolete active evasion of symbiont immune response via regulation of symbiont cytokine network biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051848 active immune evasion via regulation of symbiont cytokine network|active evasion of symbiont immune response via regulation of symbiont cytokine network|active immune evasion via modulation of symbiont cytokine network OBSOLETE. Any mechanism of active immune avoidance which works by regulating symbiont cytokine networks, e.g. by secreting proteins that mimic cytokine receptors that act to sequester symbiont cytokines and inhibit action. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0036266 Cdc48p-Npl4p-Vms1p AAA ATPase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036266 Vms1-Cdc48-Npl4 complex|Vms1p-Cdc48p-Npl4p complex|Cdc48p-Npl4p-Vms1p complex A multiprotein ATPase complex involved in the release of polyubiquitinated proteins, including those damaged by oxidative stress, from the outer mitochondria membrane into the cytoplasm where they are presented to the proteasome for proteolysis, a process also referred to as mitochondria-associated degradation (MAD). In budding yeast, this complex includes Cdc48p, Npl4p and Vms1p. GO:0036267 invasive filamentous growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036267 invasive growth The growth of colonies in filamentous chains of cells into a substrate. CHEBI:90749 antidote to cyanide poisoning biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90749 GO:0036268 swimming biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036268 Self-propelled movement of an organism from one location to another through water, often by means of active fin movement. GO:0036269 swimming behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036269 swimming behaviour The response to external or internal stimuli that results in the locomotory process of swimming. Swimming is the self-propelled movement of an organism through the water. CHEBI:90740 dihydronaphthalenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90740 CHEBI:75121 (11Z)-octadecenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75121 CHEBI:75122 1-oleoyl-2-(11Z)-octadecenoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75122 GO:0036260 RNA capping biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036260 The sequence of enzymatic reactions by which a cap structure is added to the 5' end of nascent RNA polymerase transcripts. Examples of RNA capping include 7-methyl-G caps found on all RNA polymerase II transcripts and nucleotide-containing cofactor caps, such as NAD(H) or FAD, found on bacterial trancripts. GO:0036261 7-methylguanosine cap hypermethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036261 m(7)G cap hypermethylation|hypermethylation of snRNA cap|snRNA capping|conversion of m(7)G to m(3)G|TMG cap formation|hypermethylation of snoRNA cap|2,2,7-trimethylguanosine cap formation|snoRNA capping Hypermethylation of the 7-(mono)methylguanosine (m(7)G) cap structure at the 2' position of the guanosine residue to convert a mono-methylated cap to a 2,2,7-trimethylguanosine cap structure. This type of cap modification occurs on small nuclear RNAs (snRNAs) and small nucleolar RNAs (snoRNAs) and is dependent on prior guanine-N7 methylation. GO:0036262 granulysin production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0036262 The appearance of granulysin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0036263 L-DOPA monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036263 Catalysis of the reaction: L-DOPA + O2 = ? + H2O. This reaction catalyzes the oxygenation of the dopamine precursor L-DOPA, to the corresponding o-quinone. GO:0036264 dopamine monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036264 Catalysis of the reaction: dopamine + O2 = ? + H2O. This reaction catalyzes the oxygenation of dopamine to the corresponding o-quinone. CHEBI:75123 (6Z)-octadecenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75123 CHEBI:75124 1-oleoyl-2-(6Z)-octadecenoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75124 GO:0036265 RNA (guanine-N7)-methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036265 The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an RNA molecule. GO:0051852 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051852 GO:0051853 obsolete induction in symbiont of tumor, nodule, or growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051853 induction in symbiont of tumor, nodule, or growth OBSOLETE. The process by which an associated organism causes the formation of an abnormal mass of cells in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0051850 acquisition of nutrients from symbiont biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051850 The production of structures and/or molecules in an organism that are required for the acquisition and/or utilization of nutrients obtained from its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:75139 2-oleoyl-2'-monolysocardiolipin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75139 GO:0051851 modulation by host of symbiont process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051851 modification by host of symbiont morphology or physiology The process in which an organism effects a change in the structure or processes of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0051856 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051856 GO:0051857 obsolete growth or development of organism on or near symbiont surface biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051857 growth or development of organism during interaction with symbiont|growth or development of organism on or near symbiont surface OBSOLETE. The increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring on or near the exterior of its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0051854 obsolete induction in symbiont of tumor, nodule, or growth containing transformed cells biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051854 induction in symbiont of tumor, nodule, or growth containing transformed cells OBSOLETE. The process by which an organism causes the formation in its symbiont organism of an abnormal growth whose cells have been transformed and continue to exist in the absence of the first organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0051855 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051855 GO:0051858 obsolete avoidance of symbiont defenses biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051858 OBSOLETE. Any process, either constitutive or induced, by which an organism evades, minimizes, or suppresses the effects of its symbiont organism's defense(s). The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0051859 obsolete suppression of symbiont defenses biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051859 OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont defense(s) by active mechanisms that normally result in the shutting down of a symbiont pathway. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0036255 response to methylamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036255 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylamine stimulus. GO:0036256 cellular response to methylamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036256 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylamine stimulus. GO:0036257 multivesicular body organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036257 MVB organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a multivesicular body. A multivesicular body is a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm. GO:0036258 multivesicular body assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036258 multivesicular body biogenesis|MVB formation|MVB biogenesis The aggregation, arrangement and bonding together of a set of components to form a multivesicular body, a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm. GO:0036259 aerobic raffinose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036259 aerobic raffinose degradation|aerobic raffinose breakdown|aerobic raffinose catabolism The chemical reactions and pathways resulting in the breakdown of raffinose that occur in the presence of oxygen. CHEBI:90778 C-terminal Gly-Gly(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90778 CHEBI:90779 S-substituted glutathione(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90779 CHEBI:90774 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-mono(long-chain acyl)-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90774 GO:0036250 peroxisome transport along microtubule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036250 The directed movement of a peroxisome along a microtubule, mediated by motor proteins. CHEBI:90776 11-oxo-ETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90776 GO:0036251 obsolete positive regulation of transcription from RNA polymerase II promoter in response to salt stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036251 OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under salt stress. The stress is usually an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. CHEBI:90770 3-(beta-D-galactosyl)mono(long-chain acyl)-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90770 GO:0036252 positive regulation of transcription from RNA polymerase II promoter in response to menadione biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036252 positive regulation of transcription from RNA polymerase II promoter in response to menadione stress Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a menadione stimulus. Menadione (also called vitamin K3) is a naphthoquinone having a methyl substituent at the 2-position. CHEBI:75137 2,2'-dilysocardiolipin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75137 CHEBI:75134 1-oleoyl-2-icosanoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75134 GO:0036253 response to amiloride biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036253 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amiloride stimulus. CHEBI:90772 12(S)-HpEPE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90772 GO:0036254 cellular response to amiloride biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036254 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amiloride stimulus. GO:0051863 obsolete translocation of DNA into symbiont biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051863 translocation of DNA into symbiont OBSOLETE. The directed movement of DNA from an organism to a location inside the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0051864 histone demethylase activity (H3-K36 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051864 RHEA:42032|EC:1.14.11.27|MetaCyc:RXN-8661|MetaCyc:RXN-8660 JHDM1A activity|[histone-H3]-lysine-36 demethylase activity|histone-lysine demethylase activity (H3-K36 specific)|histone-lysine(H3-K36) demethylase activity|JmjC domain-containing histone demethylase 1A activity|protein-N6,N6-dimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase activity|histone H3-lysine-36 demethylase activity|histone-lysine (H3-K36) demethylase activity|H3-K36-specific demethylase activity|protein-6-N,6-N-dimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase activity Catalysis of the reaction: histone H3 N6-methyl-L-lysine (position 36) + alpha-ketoglutarate + O2 = succinate + CO2 + formaldehyde + lysine. This reaction is the removal of a methyl group from lysine at position 36 of the histone H3 protein. GO:0051861 glycolipid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051861 Interacting selectively and non-covalently with a glycolipid, any compound containing one or more monosaccharide residues bound by a glycosidic linkage to a hydrophobic group such as an acylglycerol, a sphingoid, a ceramide (N-acylsphingoid) or a prenyl phosphate. GO:0051862 translocation of molecules into symbiont biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051862 transport of molecules into symbiont The directed movement of molecule(s) produced by an organism to a location inside the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0051867 general adaptation syndrome, behavioral process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051867 behavioural process during general adaptation syndrome|behavioural response during general adaptation syndrome|general adaptation syndrome, behavioral response|behavioral response during general adaptation syndrome|general adaptation syndrome, behavioural process|behavioral process during general adaptation syndrome|general adaptation syndrome, behavioural response The set of behavioral processes that occur as part of the general adaptation syndrome, the response of the body to a strong, stressful stimulus. GO:0051868 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051868 GO:0051865 protein autoubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051865 protein self-ubiquitination|protein auto-ubiquitination|protein autoubiquitinylation|protein self-ubiquitinylation|protein auto-ubiquitinylation The ubiquitination by a protein of one or more of its own amino acid residues, or residues on an identical protein. Ubiquitination occurs on the lysine residue by formation of an isopeptide crosslink. GO:0051866 general adaptation syndrome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051866 general adaptation syndrome, physiological response|physiological process during general adaptation syndrome|general adaptation syndrome, physiological process|physiological response during general adaptation syndrome General adaptation syndrome is the set of changes in various organ systems of the body, especially the pituitary-endocrine system, in response to a wide range of strong external stimuli, both physiological and psychological. It is described as having three stages: alarm reaction, where the body detects the external stimulus; adaptation, where the body engages defensive countermeasures against the stressor; and exhaustion, where the body begins to run out of defenses. GO:0051869 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051869 GO:0036244 cellular response to neutral pH biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036244 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a neutral pH (pH close to 7) stimulus. pH is a measure of the acidity or basicity of an aqueous solution. GO:0036245 cellular response to menadione biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036245 cellular response to vitamin K3 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menadione stimulus. Menadione (also called vitamin K3) is a naphthoquinone having a methyl substituent at the 2-position. GO:0036246 phytochelatin 2 import into vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036246 PC2 import into vacuole The directed movement of phytochelatin 2 (PC2) into the vacuole. Phytochelatin 2 is a glutathione-related peptide composed of (gamma-Glu-Cys)n-Gly where n=2, and where the Glu and Cys residues are linked through a gamma-carboxylamide bond. GO:0036247 phytochelatin 3 import into vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036247 PC3 import into vacuole The directed movement of phytochelatin 3 (PC3) into the vacuole. Phytochelatin 3 is a glutathione-related peptide composed of (gamma-Glu-Cys)n-Gly where n=3, and where the Glu and Cys residues are linked through a gamma-carboxylamide bond. GO:0036248 phytochelatin 4 import into vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036248 PC4 import into vacuole The directed movement of phytochelatin 4 (PC4) into the vacuole. Phytochelatin 4 is a glutathione-related peptide composed of (gamma-Glu-Cys)n-Gly where n=4, and where the Glu and Cys residues are linked through a gamma-carboxylamide bond. GO:0036249 cadmium ion import into vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036249 vacuolar cadmium import The directed movement of cadmium ions into the vacuole. CHEBI:75140 2'-oleoylcardiolipin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75140 CHEBI:90768 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-monooctanoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90768 CHEBI:90769 3-(beta-D-galactosyl)monooctanoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90769 CHEBI:90762 N-acetyl-D-glucosaminyl-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90762 CHEBI:90763 N-acetyl-D-glucosaminyl-(1->4)-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90763 CHEBI:75141 1-arachidonoyl-2-oleoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75141 GO:0036240 septal periplasm biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036240 cell wall-enclosed septal periplasm The region between the plasma membrane and the cell wall, as found in organisms such as filamentous fungi. CHEBI:75147 1-(alk-1-enyl)-2-oleoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75147 GO:0036241 glutamate catabolic process to 4-hydroxybutyrate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036241 glutamate degradation to 4-hydroxybutyrate The chemical reactions and pathways resulting in the breakdown of glutamate into 4-hydroxybutyrate. CHEBI:75148 1-(alk-1-enyl)-2-oleoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75148 GO:0051860 obsolete evasion or tolerance of symbiont defenses biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051860 OBSOLETE. The process, either active or passive, by which an organism evades or tolerates the effects of the defense(s) or defense molecules of a symbiont organism. Symbiont defenses may be induced by the presence of the organism or may be preformed (e.g. physical barriers). The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0036242 glutamate catabolic process to succinate via 2-oxoglutarate-dependent GABA-transaminase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036242 MetaCyc:PWY-4321|MetaCyc:PWY3O-210 glutamate degradation via gamma aminobutyrate transaminase activity The chemical reactions and pathways resulting in the breakdown of glutamate into succinate, that includes the conversion of 4-aminobutyrate to succinate semialdehyde by the 2-oxoglutarate-dependent gamma aminobutyrate (GABA) transaminase. CHEBI:51197 calixaromatic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51197 GO:0036243 succinate-semialdehyde dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036243 RHEA:13213|EC:1.2.1.79 succinate semialdehyde:NADP+ oxidoreductase activity|succinic semialdehyde dehydrogenase (NADP+) activity|succinyl semialdehyde dehydrogenase (NADP+) activity|NADP-dependent succinate-semialdehyde dehydrogenase activity Catalysis of the reaction: succinate semialdehyde + NADP+ + H2O = succinate + NADPH + 2 H+. CHEBI:90761 2-deoxy-D-ribofuranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90761 CHEBI:75954 vancomycin aglycone zwitterion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75954 CHEBI:75953 devancoaminyl vancomycin zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75953 CHEBI:75956 galactosylceramide sulfate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75956 CHEBI:51985 alpha-linolenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51985 CHEBI:75957 dTDP-beta-L-4-epi-vancosamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75957 UBERON:0013774 diaphysis of metatarsal bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013774 shaft of metatarsal bone|diaphysis of metatarsal|metatarsal bone diaphysis|metatarsal diaphysis A diaphysis that is part of a metatarsal bone. CHEBI:61310 chromium ion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61310 UBERON:0013772 left nipple biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013772 A nipple that is in_the_left_side_of a body proper. UBERON:0013773 right nipple biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013773 A nipple that is in_the_right_side_of a body proper. GO:0120299 peptide histaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120299 RHEA:66564 Catalysis of the reaction: histamine + L-glutaminyl-[protein] = 5-histaminyl-L-glutamyl-[protein]. CHEBI:61313 C21-steroid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61313 CHEBI:61314 XTP(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61314 CHEBI:36347 nuclear particle biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36347 CHEBI:36344 hadron biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36344 CHEBI:61312 5-hydroxypseudobaptigenin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61312 GO:0120295 histone serotonyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120295 Catalysis of the reaction: L-glutaminyl-[histone] + serotonin = 5-serotonyl-L-glutamyl-[histone] + NH4(+). CHEBI:61317 cyanidin 3-O-(2-O-beta-D-glucuronosyl)-beta-D-glucoside betaine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61317 CHEBI:61318 cyanidin 3-O-beta-D-glucoside betaine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61318 GO:0120296 peptide dopaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120296 RHEA:66556 Catalysis of the reaction: dopamine + L-glutaminyl-[protein] = 5-dopaminyl-L-glutamyl-[protein] + NH4(+). UBERON:0013768 great vessel of heart biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013768 great vessel of thorax|great vessel Great vessels is a term used to refer collectively to the large vessels that bring blood to and from the heart. UBERON:0013769 uterine lumen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013769 uterine space|cavity of uterus|uterine cavity A organ cavity that is part of a uterus. GO:0120297 histone dopaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120297 Catalysis of the reaction: dopamine + L-glutaminyl-[histone] = 5-dopaminyl-L-glutamyl-[histone] + NH4(+). CHEBI:61316 (3Z)-hex-3-en-1-yl acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61316 GO:0120298 peptide noradrenalinyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120298 RHEA:66560 Catalysis of the reaction: (R)-noradrenaline + L-glutaminyl-[protein] = 5-(R)-noradrenalinyl-L-glutamyl-[protein] + NH4(+). GO:0120291 negative regulation of mitotic recombination involved in replication fork processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120291 negative regulation of template switch recombination involved in replication fork processing|maintenance of template fidelity during replication fork processing|suppression of template switching during replication fork processing Any process that inhibits or decreases the rate of mitotic DNA recombination during replication fork processing. Suppression of recombination at replication forks is necessary to prevent template switching. GO:0120292 positive regulation of mitotic recombination-dependent replication fork processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120292 positive regulation of homologous recombination dependent replication fork recovery|positive regulation of recombination-dependent DNA replication|positive regulation of homologous recombination-dependent replication fork processing Any process that activates or increases the frequency, rate or extent of replication fork processing that includes recombination between DNA near the arrested fork and homologous sequences. Proteins involved in homologous recombination are required for replication restart. GO:0120293 dynein axonemal particle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120293 DynAP An aggregation of axonemal dyneins, their specific assembly factors, and broadly-acting chaperones that is located in the cytoplasm. GO:0120294 peptide serotonyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120294 RHEA:66552 Catalysis of the reaction: L-glutaminyl-[protein] + serotonin = 5-serotonyl-L-glutamyl-[protein] + NH4(+). CHEBI:36342 subatomic particle biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36342 CHEBI:75950 (20S)-protopanaxadiol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75950 CHEBI:75951 protopanaxatriol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75951 CHEBI:36343 composite particle biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36343 CHEBI:36340 fermion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36340 GO:0120290 stalled replication fork localization to nuclear periphery biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120290 stalled replication fork localization to nuclear periphery involved in replication fork processing A cellular localization process where a DNA replication fork that has stalled is signaled to relocate and anchor to the nuclear periphery for the time necessary to complete recombination-dependent replication. CHEBI:36341 boson biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36341 CHEBI:51978 oxonium betaine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51978 CHEBI:75963 chloroorienticin B(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75963 CHEBI:51972 12'-apo-carotenal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_51972 CHEBI:51973 9-cis-epoxycarotenoid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_51973 CHEBI:75967 nicotinate-adenine dinucleotide phosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75967 UBERON:0013765 digestive system element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013765 digestive system organ|digestive organ Any of the organs or elements that are part of the digestive system. Examples: tongue, esophagus, spleen, crop, lunge feeding organ, tooth elements. UBERON:0013760 external cervical os biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013760 external os|ostium uteri|external os of uterus|ostium of uterus Opening of uterine cervix into the vagina. UBERON:0013761 cervical cavity biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013761 endocervical canal|cervical canal of uterus|cavity of cervix|endocervix|canal of the cervix|cervical canal|lumen of cervix of uterus|endocervical The cavity formed by the walls of the cervix. CHEBI:36357 polyatomic entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36357 CHEBI:36358 polyatomic ion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36358 CHEBI:61323 pratensein(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61323 UBERON:0013756 venous blood biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013756 blood in vein|venous blood|portion of venous blood A blood that is part of a vein. UBERON:0013757 capillary blood biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013757 portion of blood in capillary|blood in capillary|portion of capillary blood A blood that is part of a capillary. UBERON:0013758 cervical os biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013758 cervical opening|uterine cervix opening One of two openings in the uterine cervix. CHEBI:36359 phosphorus oxoacid derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36359 CHEBI:75977 (S)-2-hydroxyhexadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75977 CHEBI:51967 monochlorobenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51967 CHEBI:51961 sesquarterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51961 CHEBI:51963 hopanoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51963 UBERON:0013752 diaphysis of metacarpal bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013752 corpus ossis metacarpi|body of metacarpal|shaft of metacarpal bone|metacarpal bone diaphysis|shaft of metacarpal A diaphysis that is part of a metacarpal bone. UBERON:0013753 distal epiphysis of metacarpal bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013753 distal end of metacarpal bone|lower end of metacarpal bone|caput ossis metacarpi|head of metacarpal bone A distal epiphysis that is part of a metacarpal bone. UBERON:0013754 integumentary system layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013754 layer of skin|skin layer A organ component layer that is part of a integumental system. UBERON:0013755 arterial blood biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013755 blood in artery|arterial blood|portion of arterial blood A blood that is part of a artery. UBERON:0013750 metaphysis of tibia biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013750 tibial metaphysis A metaphysis that is part of a tibia. CHEBI:85300 N(1),N(8)-bis(sinapoyl)-spermidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85300 CHEBI:61330 icosapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61330 CHEBI:85301 N-(decanoyl)ethanolamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85301 UBERON:0013749 metaphysis of humerus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013749 humeral metaphysis|diaphyseal end of humerus A metaphysis that is part of a metaphysis. CHEBI:85302 N-(octanoyl)ethanolamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85302 CHEBI:85303 N-(hexanoyl)ethanolamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85303 CHEBI:61336 C4-dicarboxylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61336 CHEBI:85304 N-(butanoyl)ethanolamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85304 CHEBI:85305 S-3-[(2R)-phycourobilin]-L-cysteine(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85305 CHEBI:85306 D-alloisoleucine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85306 CHEBI:61339 5-hydroxypseudobaptigenin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61339 CHEBI:36328 HODE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36328 CHEBI:85307 heparosan D-glucuronic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85307 CHEBI:36329 HPODE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36329 CHEBI:36326 octadecanoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36326 CHEBI:85308 heparosan L-iduronic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85308 CHEBI:61338 bacillithiol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61338 CHEBI:75972 (R)-2-hydroxyhexadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75972 CHEBI:36321 porphyrinogens biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36321 CHEBI:75970 2'-phospho-cyclic ADP-ribose(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75970 CHEBI:75989 alpha-D-glucosamine 6-phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75989 CHEBI:51958 organic polycyclic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51958 CHEBI:51959 organic tricyclic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51959 CHEBI:61346 achromobactin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61346 CHEBI:36335 trypanocidal drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36335 CHEBI:36336 naphthalenesulfonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36336 CHEBI:36333 local anaesthetic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36333 CHEBI:61344 (S)-beta-macrocarpene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61344 CHEBI:61345 chrysobactin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61345 CHEBI:36334 naphthalene-1,3,5-trisulfonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36334 CHEBI:36339 baryon biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36339 CHEBI:12387 beta-L-fucose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_12387 CHEBI:36338 lepton biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36338 CHEBI:36331 octadeca-10,12-dienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36331 CHEBI:36330 senecionan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36330 CHEBI:26987 threonine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26987 CHEBI:75999 (S)-laudanine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75999 CHEBI:75996 2-arachidonoyl-2'-monolysocardiolipin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75996 CHEBI:26984 threonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26984 CHEBI:26986 threonine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26986 CHEBI:26980 tetritol phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26980 CHEBI:26981 threitol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26981 CHEBI:36309 cyclic tetrapyrrole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36309 GO:0120259 7SK snRNP biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120259 snRNP 7SK A ribonucleoprotein complex that contains the 7SK snRNA. The 7SK snRNP plays a central role in RNA polymerase II elongation control by regulating the availability of active P-TEFb. GO:0120255 olefinic compound biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120255 alkene substituted compound biosynthesis|alkene substituted compound biosynthetic process|alkene substituted compound anabolism|alkene substituted compound synthesis|alkene substituted compound anabolic process The chemical reactions and pathways resulting in the formation of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C). CHEBI:36302 icosa-5,8,12,14-tetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36302 GO:0120256 olefinic compound catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120256 alkene substituted compound degradation|alkene substituted compound catabolism|alkene substituted compound breakdown|alkene substituted compound catabolic process The chemical reactions and pathways resulting in the breakdown of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C). CHEBI:12336 alpha-cyclopiazonic acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_12336 GO:0120257 peptidyl-threonine acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120257 The acetylation of peptidyl-threonine. CHEBI:36300 tricarboxylic acid dianion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36300 CHEBI:61355 3-hydroxy carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61355 GO:0120258 peptidyl-threonine O-acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120258 RESID:AA0364 The acetylation of peptidyl-threonine to form peptidyl-O-acetyl-L-threonine. CHEBI:36301 ferroheme o biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36301 CHEBI:36306 icosa-5,8,11,14-tetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36306 GO:0120251 hydrocarbon biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120251 hydrocarbon anabolism|hydrocarbon synthesis|hydrocarbon biosynthesis|hydrocarbon formation The chemical reactions and pathways resulting in the formation of a hydrocarbon, a compound consisting of carbon and hydrogen only. GO:0120252 hydrocarbon metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120252 hydrocarbon metabolism The chemical reactions and pathways involving a hydrocarbon, a compound consisting of carbon and hydrogen only. CHEBI:85329 UDP-4-dehydro-6-deoxy-alpha-D-glucose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85329 CHEBI:36307 glycosyl alditol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36307 GO:0120253 hydrocarbon catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120253 hydrocarbon degradation|hydrocarbon breakdown|hydrocarbon catabolism The chemical reactions and pathways resulting in the breakdown of a hydrocarbon, a compound consisting of carbon and hydrogen only. GO:0120254 olefinic compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120254 alkene substituted compound metabolic process|alkene substituted compound metabolism The chemical reactions and pathways involving an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C). CHEBI:75990 2'-capryloylcardiolipin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75990 GO:0120250 fatty acid omega-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120250 RHEA:39023 Catalysis of the reaction: an omega-methyl fatty acid + O2 + reduced [NADPH--hemoprotein reductase] = an omega-hydroxy fatty acid + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]. CHEBI:75994 2'-palmitoylcardiolipin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75994 CHEBI:75995 2'-arachidonoylcardiolipin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75995 CHEBI:75992 phenyl 5-phosphonato-alpha-D-ribofuranoside(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75992 CHEBI:75993 2-capryloyl-2'-monolysocardiolipin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75993 CHEBI:26995 thromboxane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26995 CHEBI:26996 thromboxanes B biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_26996 CHEBI:61360 globoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61360 CHEBI:26992 threoses biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26992 CHEBI:61362 cyclitol ether biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61362 CHEBI:85311 poly[(1->4)-beta-D-mannuronate] biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85311 CHEBI:85312 beta-D-galacturonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85312 GO:0120266 positive regulation of chromosome attachment to the nuclear envelope biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120266 stimulation of chromosome attachment to the nuclear envelope|up-regulation of chromosome attachment to the nuclear envelope|upregulation of chromosome attachment to the nuclear envelope|up regulation of chromosome attachment to the nuclear envelope|activation of chromosome attachment to the nuclear envelope Any process that activates or increases the frequency, rate or extent of the chromosome attachment to the nuclear envelope. CHEBI:85313 beta-D-glucuronate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85313 CHEBI:36313 glycerophosphocholine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36313 GO:0120267 pellicular membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120267 pellicle membrane|pellicular plasma membrane The portion of the plasma membrane surrounding the pellicle, a structure enclosing some parasite cells such as certain apicomplexa and Euglenozoa. These membranes are associated with an infrastructure of microtubules, microfilaments, and other organelles. CHEBI:36314 glycerophosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36314 GO:0120268 paraflagellar rod assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120268 PFR assembly|paraflagellar rod formation|paraflagellar rod biogenesis The aggregation, arrangement and bonding together of a set of components to form a paraflagellar rod, a large lattice-like axial structure found in some flagellated protists which extends alongside the axoneme. CHEBI:36311 corphinoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36311 CHEBI:61366 2-tetradecenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61366 GO:0120269 ciliary centrin arm biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120269 A rod-shaped protein complex containing Centrin4 protein that flanks the flagellum attachment zone (FAZ) filament and the quartet microtubules. CHEBI:36312 sarpagan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36312 CHEBI:85316 (R)-ethylmalonyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85316 GO:0120262 negative regulation of heterochromatin organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120262 down regulation of heterochromatin organization|inhibition of heterochromatin organization|negative regulation of heterochromatin organization|down-regulation of heterochromatin organization|downregulation of heterochromatin organization Any process that stops, prevents, or reduces the frequency, rate or extent of heterochromatin organization. CHEBI:85317 D-galactaro-1,4-lactone(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85317 GO:0120263 positive regulation of heterochromatin organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120263 upregulation of heterochromatin organization|stimulation of heterochromatin organization|up-regulation of heterochromatin organization|activation of heterochromatin organization|positive regulation of heterochromatin organization|up regulation of heterochromatin organization Any process that activates or increases the frequency, rate or extent of heterochromatin organization. GO:0120264 regulation of chromosome attachment to the nuclear envelope biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120264 Any process that modulates the frequency, rate, extent or location of chromosome attachment to the nuclear envelope. CHEBI:36315 glycerophosphoinositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36315 GO:0120265 negative regulation of chromosome attachment to the nuclear envelope biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120265 down-regulation of chromosome attachment to the nuclear envelope|inhibition of chromosome attachment to the nuclear envelope|down regulation of chromosome attachment to the nuclear envelope|downregulation of chromosome attachment to the nuclear envelope Any process that stops, prevents, or reduces the frequency, rate or extent of the chromosome attachment to the nuclear envelope. CHEBI:36316 dipyrrole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36316 GO:0120260 ciliary microtubule quartet biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120260 ciliary MtQ A set of four specialized microtubules that originates from the basal bodies and wraps around the ciliary pocket membrane, likely supporting its distinct flask shape. GO:0120261 regulation of heterochromatin organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120261 Any process that modulates the frequency, rate, extent or location of heterochromatin organization. CHEBI:36310 glycosylglycerol phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36310 CHEBI:51921 heptadienal biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51921 CHEBI:26965 thioglycines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26965 CHEBI:51922 (E,E)-7-hydroxy-6-methylhepta-3,5-dienal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_51922 CHEBI:26961 thiophenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26961 CHEBI:85342 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate)(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85342 CHEBI:61375 ferric-vibriobactin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61375 CHEBI:85344 (4R)-3,4-dihydro-4-hydroxyphenylpyruvic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85344 CHEBI:85346 N(3)-fumaroyl-(S)-2,3-diaminopropanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85346 GO:0120277 positive regulation of cerebral blood circulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120277 positive regulation of cerebrum blood circulation|up-regulation of cerebral blood circulation|activation of cerebral blood circulation|positive regulation of telencephalon blood circulation|up regulation of cerebral blood circulation|upregulation of cerebral blood circulation Any process that activates or increases the frequency, rate or extent of cerebral blood circulation. CHEBI:12357 beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_12357 GO:0120278 negative regulation of cerebral blood circulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120278 negative regulation of cerebrum blood circulation|down-regulation of cerebral blood circulation|negative regulation of telencephalon blood circulation|downregulation of cerebral blood circulation|down regulation of cerebral blood circulation|inhibition of cerebral blood circulation Any process that stops, prevents or reduces the frequency, rate or extent of cerebral blood circulation. CHEBI:85347 N(3)-fumaramoyl-(S)-2,3-diaminopropanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85347 GO:0120279 Z granule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120279 germline granule A small cytoplasmic, non-membranous RNA/protein complex aggregate in the primordial germ cells that are distinct from, but colocalize with or are adjacent to, P granules and mutator foci and are associated with RNA metabolism. Z granules have been observed in C. elegans. CHEBI:61377 TDP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61377 CHEBI:85348 11,12-saturated fatty acyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85348 CHEBI:85349 CDP-1-stearoyl-2-arachidonoyl-sn-glycerol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85349 CHEBI:61378 2'-(5-triphosphoribosyl)-3'-dephospho-CoA(6-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61378 GO:0120273 ciliary centrin arm assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120273 ciliary centrin arm formation The aggregation, arrangement and bonding together of a set of macromolecules to form a ciliary centrin arm, a rod-shaped protein complex containing Centrin4 protein that flanks the flagellum attachment zone (FAZ) filament and the quartet microtubules. GO:0120274 virus coreceptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120274 viral coreceptor activity Combining with a virus component, and in cooperation with a nearby primary receptor, initiating a change in cell activity. GO:0120275 cerebral blood circulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120275 telencephelon blood circulation|cerebrum blood circulation The flow of blood through the network of arteries and veins supplying the cerebrum, enabling the transport of nutrients to the tissues and the removal of waste products. GO:0120276 regulation of cerebral blood circulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120276 regulation of telencephalon blood circulation|regulation of cerebrum blood circulation Any process that modulates the frequency, rate or extent of cerebral blood circulation. GO:0120270 regulation of nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120270 Any process that modulates the rate, frequency, or extent of selective degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein. CHEBI:12350 beta-D-fructofuranose 2-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_12350 GO:0120271 negative regulation of nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120271 Any process that stops, prevents or reduces the frequency, rate or extent of selective degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein. GO:0120272 positive regulation of nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120272 Any process that activates or increases the frequency, rate or extent of degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein. CHEBI:26976 thioribose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26976 CHEBI:26977 thiosulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26977 CHEBI:26979 organic heterotricyclic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26979 CHEBI:26975 thioribose phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26975 CHEBI:61382 dITP(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61382 CHEBI:61383 dTDP-4-acetamido-4,6-dideoxy-D-glucose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61383 CHEBI:61380 acetylenic fatty acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61380 CHEBI:85330 dapdiamide A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85330 CHEBI:61381 D-mannitol 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61381 CHEBI:61386 UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alaninate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61386 CHEBI:51914 organic heterohexacyclic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51914 CHEBI:85331 dapdiamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85331 CHEBI:61387 undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61387 CHEBI:51915 indolocarbazole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51915 CHEBI:85332 dapdiamide B biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85332 CHEBI:85333 dapdiamide C biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85333 CHEBI:61384 sulfolipid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61384 CHEBI:61385 UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-D-glucosamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61385 CHEBI:85334 N,1-dipalmitoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85334 GO:0120288 negative regulation of aspartic endopeptidase activity, intramembrane cleaving biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120288 Any process that decreases the frequency, rate or extent of intramembrane cleaving aspartic-type endopeptidase activity. CHEBI:85335 N,1-dipalmitoyl-sn-glycero-3-phosphoethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85335 GO:0120289 positive regulation of aspartic endopeptidase activity, intramembrane cleaving biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120289 Any process that increases the frequency, rate or extent of intramembrane cleaving aspartic-type endopeptidase activity. CHEBI:85336 D-glucaro-1,4-lactone(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85336 CHEBI:61388 undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61388 CHEBI:85337 dapdiamide E biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85337 CHEBI:85338 L-alloisoleucine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85338 GO:0120284 tryptophan binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120284 Trp binding Interacting selectively and non-covalently with 2-amino-3-(1H-indol-3-yl)propanoic acid. CHEBI:85339 O-[S-(L-alloisoleucyl)pantetheine-4'-phosphoryl]serine zwitterionic residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85339 GO:0120285 tyrosine sensor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120285 Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of tyrosine. GO:0120286 tryptophan sensor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120286 Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of tryptophan. GO:0120287 regulation of aspartic endopeptidase activity, intramembrane cleaving biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120287 Any process that modulates the frequency, rate or extent of intramembrane cleaving aspartic-type endopeptidase activity. GO:0120280 ciliary pro-basal body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120280 flagellar pro-basal body|pro-basal body|probasal body|flagellar probasal body|pro-centriole The cilary pro-basal body is an immature, partially assembled form of a ciliary basal body found next to the basal body of a cilium. Pro-basal bodies are not capable of nucleating a cilium. As the cell progresses through the cell cycle, continuing assembly will convert the pro-basal body into a mature basal body that is capable of nucleating a cilium. GO:0120281 autolysosome membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120281 A lipid bilayer that surrounds an autolysosome, a single-membrane-bounded vesicle in which endogenous cellular material is degraded. GO:0120282 autolysosome lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120282 The volume that is enclosed within the autolysosome single-membrane. GO:0120283 protein serine/threonine kinase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120283 Interacting selectively and non-covalently with a protein serine/threonine kinase. CHEBI:131436 N-acetyl-L-phosphinothricin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131436 GO:1901169 3-chlorocatechol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901169 3-chlorocatechol anabolism|3-chlorocatechol synthesis|3-chlorocatechol formation|3-chlorocatechol biosynthesis The chemical reactions and pathways resulting in the formation of 3-chlorocatechol. GO:1901167 3-chlorocatechol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901167 3-chlorocatechol metabolism The chemical reactions and pathways involving 3-chlorocatechol. GO:1901168 3-chlorocatechol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901168 3-chlorocatechol degradation|3-chlorocatechol breakdown|3-chlorocatechol catabolism The chemical reactions and pathways resulting in the breakdown of 3-chlorocatechol. GO:1901165 positive regulation of trophoblast cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901165 up regulation of trophoblast cell migration|upregulation of trophoblast cell migration|up-regulation of trophoblast cell migration|activation of trophoblast cell migration Any process that activates or increases the frequency, rate or extent of trophoblast cell migration. GO:1901166 neural crest cell migration involved in autonomic nervous system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901166 Any neural crest cell migration that is involved in autonomic nervous system development. GO:1901174 phytoene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901174 phytoene anabolism|phytoene synthesis|phytoene formation|phytoene biosynthesis The chemical reactions and pathways resulting in the formation of phytoene. GO:1901175 lycopene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901175 lycopene metabolism The chemical reactions and pathways involving lycopene. GO:1901172 phytoene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901172 phytoene metabolism The chemical reactions and pathways involving phytoene. GO:1901173 phytoene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901173 phytoene breakdown|phytoene catabolism|phytoene degradation The chemical reactions and pathways resulting in the breakdown of phytoene. GO:1901170 naphthalene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901170 naphthalene catabolism|naphthalene degradation|naphthalene breakdown The chemical reactions and pathways resulting in the breakdown of naphthalene. GO:1901171 naphthalene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901171 naphthalene formation|naphthalene biosynthesis|naphthalene anabolism|naphthalene synthesis The chemical reactions and pathways resulting in the formation of naphthalene. GO:0061390 positive regulation of direction of cell growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061390 Any process that increases the direction of cell growth. CHEBI:131447 2-aminobenzoylacetyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131447 GO:0061391 negative regulation of direction of cell growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061391 Any process that decreases the direction of cell growth. CHEBI:131448 beta-D-Manp-(1->2)-beta-D-Manp-(1->2)-D-Manp biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131448 GO:0061392 obsolete regulation of transcription from RNA polymerase II promoter in response to osmotic stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061392 OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. GO:0061393 obsolete positive regulation of transcription from RNA polymerase II promoter in response to osmotic stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061393 OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. GO:1901178 spheroidene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901178 spheroidene metabolism The chemical reactions and pathways involving spheroidene. GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061394 Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides. GO:0061395 positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061395 Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides. GO:1901179 spheroidene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901179 spheroidene catabolism|spheroidene degradation|spheroidene breakdown The chemical reactions and pathways resulting in the breakdown of spheroidene. GO:1901176 lycopene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901176 lycopene breakdown|lycopene degradation|lycopene catabolism The chemical reactions and pathways resulting in the breakdown of lycopene. GO:0061396 obsolete regulation of transcription from RNA polymerase II promoter in response to copper ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061396 OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to an copper ion stimulus. GO:1901177 lycopene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901177 lycopene biosynthesis|lycopene anabolism|lycopene synthesis|lycopene formation The chemical reactions and pathways resulting in the formation of lycopene. GO:0061397 obsolete positive regulation of transcription from RNA polymerase II promoter in response to copper ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061397 OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to an copper ion stimulus. GO:1901185 negative regulation of ERBB signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901185 negative regulation of EGF receptor family signaling pathway|down-regulation of EGF receptor family signaling pathway|inhibition of ERBB signalling pathway|inhibition of ErbB signaling|down-regulation of ERBB signaling pathway|inhibition of EGFR family signaling pathway|down regulation of ERBB signalling pathway|downregulation of ERBB signaling pathway|downregulation of ERBB signalling pathway|inhibition of EGF receptor family signaling pathway|down-regulation of ErbB signaling|negative regulation of ErbB signaling|down regulation of EGFR family signaling pathway|down regulation of ERBB signaling pathway|inhibition of ERBB signaling pathway|downregulation of EGFR family signaling pathway|down regulation of EGF receptor family signaling pathway|down-regulation of ERBB signalling pathway|negative regulation of ERBB signalling pathway|downregulation of ErbB signaling|downregulation of EGF receptor family signaling pathway|down regulation of ErbB signaling|negative regulation of EGFR family signaling pathway|down-regulation of EGFR family signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of ERBB signaling pathway. GO:0061398 obsolete negative regulation of transcription from RNA polymerase II promoter in response to copper ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061398 OBSOLETE. Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to an copper ion stimulus. GO:1901186 positive regulation of ERBB signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901186 upregulation of ErbB signaling|activation of EGF receptor family signaling pathway|up-regulation of EGFR family signaling pathway|upregulation of ERBB signalling pathway|up-regulation of ErbB signaling|up-regulation of EGF receptor family signaling pathway|up regulation of ERBB signaling pathway|upregulation of EGFR family signaling pathway|activation of ErbB signaling|up regulation of ERBB signalling pathway|upregulation of EGF receptor family signaling pathway|positive regulation of ErbB signaling|positive regulation of ERBB signalling pathway|upregulation of ERBB signaling pathway|up regulation of ErbB signaling|up regulation of EGFR family signaling pathway|activation of ERBB signalling pathway|positive regulation of EGFR family signaling pathway|up regulation of EGF receptor family signaling pathway|activation of ERBB signaling pathway|up-regulation of ERBB signaling pathway|positive regulation of EGF receptor family signaling pathway|activation of EGFR family signaling pathway|up-regulation of ERBB signalling pathway Any process that activates or increases the frequency, rate or extent of ERBB signaling pathway. GO:0061399 positive regulation of transcription from RNA polymerase II promoter in response to cobalt ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061399 Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to a cobalt ion stimulus. GO:1901183 positive regulation of camalexin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901183 up regulation of camalexin biosynthesis|up regulation of camalexin anabolism|up regulation of camalexin biosynthetic process|positive regulation of camalexin anabolism|up regulation of camalexin synthesis|positive regulation of camalexin synthesis|up regulation of camalexin formation|activation of camalexin anabolism|positive regulation of camalexin formation|upregulation of camalexin biosynthesis|upregulation of camalexin biosynthetic process|activation of camalexin synthesis|up-regulation of camalexin anabolism|activation of camalexin formation|up-regulation of camalexin synthesis|up-regulation of camalexin biosynthesis|up-regulation of camalexin biosynthetic process|activation of camalexin biosynthetic process|up-regulation of camalexin formation|upregulation of camalexin anabolism|activation of camalexin biosynthesis|upregulation of camalexin synthesis|upregulation of camalexin formation|positive regulation of camalexin biosynthesis Any process that activates or increases the frequency, rate or extent of camalexin biosynthetic process. GO:1901184 regulation of ERBB signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901184 regulation of ERBB signalling pathway|regulation of EGFR family signaling pathway|regulation of EGF receptor family signaling pathway|regulation of ErbB signaling Any process that modulates the frequency, rate or extent of ERBB signaling pathway. GO:1901181 negative regulation of cellular response to caffeine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901181 inhibition of cellular response to caffeine|down regulation of cellular response to caffeine|downregulation of cellular response to caffeine|down-regulation of cellular response to caffeine Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to caffeine. GO:1901182 regulation of camalexin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901182 regulation of camalexin synthesis|regulation of camalexin formation|regulation of camalexin biosynthesis|regulation of camalexin anabolism Any process that modulates the frequency, rate or extent of camalexin biosynthetic process. CHEBI:131444 guanidinoacetate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131444 CHEBI:131445 4-methylpentanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131445 GO:1901180 spheroidene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901180 spheroidene biosynthesis|spheroidene anabolism|spheroidene synthesis|spheroidene formation The chemical reactions and pathways resulting in the formation of spheroidene. CHEBI:131446 2-aminobenzoylacetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131446 GO:1901189 positive regulation of ephrin receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901189 up regulation of Eph receptor signalling pathway|upregulation of Eph receptor signaling pathway|positive regulation of Eph receptor signalling pathway|up regulation of ephrin receptor signaling pathway|activation of ephrin receptor signaling pathway|activation of Eph receptor signalling pathway|up-regulation of Eph receptor signaling pathway|up-regulation of Eph receptor signalling pathway|activation of Eph receptor signaling pathway|up-regulation of ephrin receptor signaling pathway|positive regulation of Eph receptor signaling pathway|up regulation of Eph receptor signaling pathway|upregulation of Eph receptor signalling pathway|upregulation of ephrin receptor signaling pathway Any process that activates or increases the frequency, rate or extent of ephrin receptor signaling pathway. GO:1901187 regulation of ephrin receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901187 regulation of Eph receptor signalling pathway|regulation of Eph receptor signaling pathway Any process that modulates the frequency, rate or extent of ephrin receptor signaling pathway. GO:1901188 negative regulation of ephrin receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901188 down regulation of ephrin receptor signaling pathway|down regulation of Eph receptor signaling pathway|downregulation of Eph receptor signalling pathway|downregulation of ephrin receptor signaling pathway|inhibition of Eph receptor signaling pathway|down-regulation of Eph receptor signalling pathway|negative regulation of Eph receptor signalling pathway|down-regulation of ephrin receptor signaling pathway|inhibition of ephrin receptor signaling pathway|down-regulation of Eph receptor signaling pathway|negative regulation of Eph receptor signaling pathway|inhibition of Eph receptor signalling pathway|down regulation of Eph receptor signalling pathway|downregulation of Eph receptor signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of ephrin receptor signaling pathway. GO:1901196 positive regulation of calcium-mediated signaling involved in cellular response to salt stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901196 up regulation of calcium-mediated signaling involved in cellular response to salt stress|activation of calcium-mediated signaling involved in cellular response to salt stress|up regulation of calcium-mediated signaling involved in cellular salinity response|activation of calcium-mediated signaling involved in cellular salinity response|stimulation of calcium-mediated signaling involved in cellular response to salt stress|positive regulation of calcium-mediated signaling involved in cellular salinity response|stimulation of calcium-mediated signaling involved in cellular salinity response|upregulation of calcium-mediated signaling involved in cellular response to ionic osmotic stress|positive regulation of calcium-mediated signalling involved in cellular response to ionic osmotic stress|stimulation of calcium-mediated signaling involved in cellular response to ionic osmotic stress|up-regulation of calcium-mediated signaling involved in cellular response to salt stress|up-regulation of calcium-mediated signaling involved in cellular response to ionic osmotic stress|activation of calcium-mediated signaling involved in cellular response to ionic osmotic stress|up-regulation of calcium-mediated signaling involved in cellular salinity response|positive regulation of calcium-mediated signalling involved in cellular response to salt stress|positive regulation of calcium-mediated signalling involved in cellular salinity response|upregulation of calcium-mediated signaling involved in cellular response to salt stress|upregulation of calcium-mediated signaling involved in cellular salinity response|positive regulation of calcium-mediated signaling involved in cellular response to ionic osmotic stress|up regulation of calcium-mediated signaling involved in cellular response to ionic osmotic stress Any positive regulation of calcium-mediated signaling that is involved in cellular response to salt stress. GO:1901197 positive regulation of calcium-mediated signaling involved in cellular response to calcium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901197 upregulation of calcium-mediated signaling involved in cellular response to calcium ion|positive regulation of calcium-mediated signaling involved in cellular response to Ca2+ ion|up-regulation of calcium-mediated signaling involved in response to calcium ion|up regulation of calcium-mediated signaling involved in cellular response to Ca2+ ion|up regulation of calcium-mediated signaling involved in cellular response to calcium ion|activation of calcium-mediated signaling involved in cellular response to calcium ion|stimulation of calcium-mediated signaling involved in cellular response to calcium ion|upregulation of calcium-mediated signaling involved in cellular response to Ca2+ ion|positive regulation of calcium-mediated signalling involved in cellular response to Ca2+ ion|stimulation of calcium-mediated signaling involved in cellular response to Ca2+ ion|up-regulation of calcium-mediated signaling involved in cellular response to Ca2+ ion|activation of calcium-mediated signaling involved in cellular response to Ca2+ ion|positive regulation of calcium-mediated signalling involved in cellular response to calcium ion Any positive regulation of calcium-mediated signaling that is involved in cellular response to calcium ion. GO:1901194 negative regulation of formation of translation preinitiation complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901194 down-regulation of formation of translation pre-initiation complex|negative regulation of formation of translation pre-initiation complex|downregulation of translation preinitiation complex assembly|downregulation of formation of translation preinitiation complex|down regulation of formation of translation preinitiation complex|down regulation of translation preinitiation complex assembly|inhibition of formation of translation pre-initiation complex|inhibition of formation of translation preinitiation complex|inhibition of translation preinitiation complex assembly|down regulation of formation of translation pre-initiation complex|downregulation of formation of translation pre-initiation complex|negative regulation of translation preinitiation complex assembly|down-regulation of formation of translation preinitiation complex|down-regulation of translation preinitiation complex assembly Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation preinitiation complex. GO:1901195 positive regulation of formation of translation preinitiation complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901195 positive regulation of translation preinitiation complex assembly|activation of formation of translation pre-initiation complex|up regulation of formation of translation preinitiation complex|up regulation of translation preinitiation complex assembly|up-regulation of formation of translation pre-initiation complex|upregulation of translation preinitiation complex assembly|upregulation of formation of translation preinitiation complex|upregulation of formation of translation pre-initiation complex|up-regulation of translation preinitiation complex assembly|up-regulation of formation of translation preinitiation complex|activation of formation of translation preinitiation complex|up regulation of formation of translation pre-initiation complex|positive regulation of formation of translation pre-initiation complex|activation of translation preinitiation complex assembly Any process that activates or increases the frequency, rate or extent of formation of translation preinitiation complex. GO:1901192 positive regulation of formation of translation initiation ternary complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901192 up regulation of translation initiation ternary complex assembly|up regulation of formation of translation initiation ternary complex|positive regulation of translation initiation ternary complex assembly|activation of formation of translation initiation ternary complex|activation of translation initiation ternary complex assembly|up-regulation of formation of translation initiation ternary complex|up-regulation of translation initiation ternary complex assembly|upregulation of formation of translation initiation ternary complex|upregulation of translation initiation ternary complex assembly Any process that activates or increases the frequency, rate or extent of formation of translation initiation ternary complex. GO:1901193 regulation of formation of translation preinitiation complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901193 regulation of translation preinitiation complex assembly|regulation of formation of translation pre-initiation complex Any process that modulates the frequency, rate or extent of formation of translation preinitiation complex. GO:1901190 regulation of formation of translation initiation ternary complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901190 regulation of translation initiation ternary complex assembly Any process that modulates the frequency, rate or extent of formation of translation initiation ternary complex. GO:1901191 negative regulation of formation of translation initiation ternary complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901191 down regulation of formation of translation initiation ternary complex|down regulation of translation initiation ternary complex assembly|downregulation of translation initiation ternary complex assembly|downregulation of formation of translation initiation ternary complex|down-regulation of formation of translation initiation ternary complex|negative regulation of translation initiation ternary complex assembly|down-regulation of translation initiation ternary complex assembly|inhibition of formation of translation initiation ternary complex|inhibition of translation initiation ternary complex assembly Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation initiation ternary complex. CHEBI:131429 carcinine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131429 GO:1901198 positive regulation of calcium ion transport into cytosol involved in cellular response to calcium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901198 positive regulation of calcium ion transport into cytosol involved in cellular response to Ca2+ ion Any positive regulation of calcium ion transport into cytosol that is involved in cellular response to calcium ion. GO:1901199 positive regulation of calcium ion transport into cytosol involved in cellular response to salt stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901199 positive regulation of calcium ion transport into cytosol involved in cellular response to ionic osmotic stress|positive regulation of calcium ion transport into cytosol involved in cellular salinity response Any positive regulation of calcium ion transport into cytosol that is involved in cellular response to salt stress. CHEBI:9330 sulfamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_9330 CHEBI:75914 1-oleoyl-2-O-arachidonyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75914 CHEBI:75913 2-arachidonyl glyceryl ether biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75913 UBERON:0013727 notochordal fluid biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013727 notochord fluid|portion of notochordal fluid Fluid contained within the notochordal canal CHEBI:36388 saturated organic heterocyclic parent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36388 CHEBI:36389 saturated organic heteromonocyclic parent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36389 CHEBI:36387 chloroalkene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36387 CHEBI:75921 (R,R)-2,3-dimethyl-6-phytylhydroquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75921 CHEBI:75920 (R,R)-2-methyl-6-phytylhydroquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75920 CHEBI:9341 sulfinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_9341 CHEBI:75925 octadecanoate ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75925 CHEBI:75926 4-hydroxy-2-quinolone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75926 CHEBI:75923 3-oxodecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75923 CHEBI:75929 D-cycloserine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75929 CHEBI:75927 (R)-2-hydroxyhexadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75927 CHEBI:75928 (S)-2-hydroxyhexadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75928 CHEBI:131401 hexopyranosyl hexopyranoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131401 CHEBI:36393 thiomorpholines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36393 CHEBI:9337 sulfathiazole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_9337 CHEBI:75932 26-desglucoavenacoside A biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75932 CHEBI:75933 4-O-(beta-L-Araf)-cis-L-Hyp biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75933 CHEBI:75931 26-desglucoavenacoside B biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75931 CHEBI:75936 1-O-palmityl-2-acetyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75936 CHEBI:75937 monooleoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75937 CHEBI:75935 (R)-2-hydroxylignocerate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75935 CHEBI:75938 3-oleoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75938 UBERON:0013701 main body axis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013701 A principle subdivision of an organism that includes all structures along the primary axis, typically the anterior-posterior axis, from head to tail, including structures of the body proper where present (for example, ribs), but excluding appendages. UBERON:0013702 body proper biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013702 body|whole body The region of the organism associated with the visceral organs. UBERON:0013703 integumentary projection biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013703 skin projection Anatomical projection that is part of the integumentl system. UBERON:0013704 notochordal canal biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013704 chordal canal A tubular passage that extends from the primitive pit into the head process during the early stages of embryonic development in mammals. It perforates the splanchnopleure layer so that the yolk sac and the amnion are connected temporarily. CHEBI:36360 phosphorus oxoacids and derivatives biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36360 CHEBI:36361 phosphorous acid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36361 CHEBI:9300 suberic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_9300 CHEBI:36363 hydroxyphosphanone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36363 CHEBI:75947 2'-3'-cGAMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75947 CHEBI:75945 dioleoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75945 CHEBI:75946 cytochalasan alkaloid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75946 UBERON:0013700 axial musculature biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013700 Musculature of the head and neck, spine, and ribs. CHEBI:61302 cerebronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61302 CHEBI:61301 germacra-1(10),4,11(13)-trien-12-oate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61301 CHEBI:61307 solavetivol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61307 CHEBI:61304 phosphoglycerate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61304 CHEBI:61305 germacra-1(10),4,11(13)-trien-12-oic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61305 GO:0051995 Se-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051995 Catalysis of the transfer of a methyl group to the selenium atom of an acceptor molecule. GO:0051996 squalene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051996 EC:2.5.1.21|MetaCyc:RXN66-281 squalene synthetase activity Catalysis of the reaction: presqualene diphosphate + NADPH = squalene + NADP+ + diphosphate. GO:0051993 abscisic acid glucose ester beta-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051993 MetaCyc:RXN-11469|EC:3.2.1.175|RHEA:31347 ABA-GE beta-glucosidase activity Catalysis of the reaction: abscisic acid glucose ester + H2O = abscisic acid + beta-D-glucose. GO:0051994 P-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051994 EC:2.1.1.- Catalysis of the transfer of a methyl group to the phosphorus atom of an acceptor molecule. GO:0051999 mannosyl-inositol phosphorylceramide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051999 mannosyl-inositol phosphorylceramide biosynthesis|mannose-inositol-P-ceramide (MIPC) biosynthetic process|mannose inositol phosphoceramide biosynthetic process|MIPC biosynthetic process|mannosyl-inositol phosphorylceramide anabolism|mannosyl-inositol phosphorylceramide synthesis|mannosyl-inositol phosphorylceramide formation The chemical reactions and pathways resulting in the formation of mannosyl-inositol phosphorylceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains a phosphoryl (-P(O)=) groups and a mannose derivative. GO:0051997 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051997 KEGG_REACTION:R06604|RHEA:26301|MetaCyc:RXN-6201 OHCU decarboxylase activity|4-(carbamoylamino)-5-hydroxy-2-oxo-2,5-dihydro-1H-imidazole-5-carboxylate decarboxylase activity Catalysis of the reaction: 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H imidazole-5-carboxylate + H+ = S-allantoin + CO2. GO:0051998 protein carboxyl O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051998 protein carboxyl methyltransferase activity Catalysis of the transfer of a methyl group to a carboxyl group on a protein. GO:2000104 negative regulation of DNA-dependent DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000104 Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent DNA replication. GO:2000105 positive regulation of DNA-dependent DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000105 Any process that activates or increases the frequency, rate or extent of DNA-dependent DNA replication. GO:2000106 regulation of leukocyte apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000106 regulation of leukocyte apoptosis Any process that modulates the frequency, rate or extent of leukocyte apoptotic process. GO:2000107 negative regulation of leukocyte apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000107 negative regulation of leukocyte apoptosis Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte apoptotic process. GO:2000108 positive regulation of leukocyte apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000108 positive regulation of leukocyte apoptosis Any process that activates or increases the frequency, rate or extent of leukocyte apoptotic process. GO:2000109 regulation of macrophage apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000109 regulation of AICD|regulation of macrophage apoptosis|regulation of activation-induced cell death Any process that modulates the frequency, rate or extent of macrophage apoptotic process. GO:0061320 pericardial nephrocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061320 pericardial cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a pericardial nephrocyte. A pericardial nephrocyte is an insect renal cell that filters hemolymph and is found with other pericardial nephrocytes in two rows flanking the dorsal vessel. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. GO:0036354 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide a dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036354 RHEA:19733|MetaCyc:RXN-8787 Catalysis of the reaction: 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide a = bacteriochlorophyllide a + 2 H+. GO:0061321 garland nephrocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061321 garland cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a garland nephrocyte. A garland nephrocyte is an insect renal cell that filters hemolymph and forms a ring with other garland nephrocytes around the esophagus. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. GO:0036355 2-iminoacetate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036355 MetaCyc:RXN-11319|EC:4.1.99.19|RHEA:26361 Catalysis of the reaction: L-tyrosine + S-adenosyl-L-methionine + reduced acceptor = 2-iminoacetate + 4-methylphenol + 5'-deoxyadenosine + L-methionine + acceptor + 2 H+. GO:0061322 disseminated nephrocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061322 The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a disseminated nephrocyte. A disseminated nephrocyte is an insect renal cell that filters hemolymph and is found at scattered locations in the fat body or other tissues. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. GO:0036356 cyclic 2,3-diphosphoglycerate synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036356 EC:4.6.1.- cDPGS activity|CPGS activity Catalysis of the reaction: 2,3-diphosphoglycerate (DPG) + ATP = cyclic 2,3-diphosphoglycerate (cDPG) + ADP + phosphate. GO:0061323 cell proliferation involved in heart morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061323 The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the heart. GO:0061324 canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061324 canonical Wnt-activated signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation|canonical Wnt receptor signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation|canonical Wnt receptor signalling pathway involved in positive regulation of cardiac outflow tract cell proliferation The canonical Wnt signaling pathway that contributes to the modulation of the expansion of a population of cardiac outflow tract cells. GO:0036357 2-phosphoglycerate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036357 EC:2.7.2.- 2PGK activity Catalysis of the reaction: 2-phosphoglycerate + ATP = 2,3-diphosphoglycerate + ADP. GO:2000100 regulation of establishment or maintenance of bipolar cell polarity regulating cell shape biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000100 Any process that modulates the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape. GO:0061325 cell proliferation involved in outflow tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061325 The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract. GO:0036358 lipoteichoic acid D-alanylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036358 D-alanyl lipoteichoic acid formation|LTA D-alanylation|D-alanyl LTA formation The formation of a D-alanyl ester of lipoteichoic acid by transfer of D-Ala onto a membrane-associated lipoteichoic acid (LTA). GO:2000101 regulation of mammary stem cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000101 Any process that modulates the frequency, rate or extent of mammary stem cell proliferation. GO:0061326 renal tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061326 The progression of the renal tubule over time from its formation to the mature form. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis. GO:0036359 renal potassium excretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036359 renal K+ elimination|renal K(+) excretion|renal potassium ion excretion The elimination by an organism of potassium in the urine. GO:2000102 negative regulation of mammary stem cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000102 Any process that stops, prevents, or reduces the frequency, rate or extent of mammary stem cell proliferation. GO:0061327 anterior Malpighian tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061327 The process whose specific outcome is the progression of the anterior Malpighian tubule over time, from its formation to the mature structure. The pair of anterior tubules arise from a dorsal region of the embryonic hindgut and projects forwards through the body cavity. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut. GO:2000103 positive regulation of mammary stem cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000103 Any process that activates or increases the frequency, rate or extent of mammary stem cell proliferation. GO:0061328 posterior Malpighian tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061328 The process whose specific outcome is the progression of the posterior Malpighian tubule over time, from its formation to the mature structure. The pair of posterior tubules arise from a ventrolateral region of the embryonic hindgut and project backwards through the body cavity. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut. GO:0061329 Malpighian tubule principal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061329 The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule principal cell. A Malpighian tubule principal cell is an epithelial secretory cell that transports cations into the lumen of the tubule. UBERON_CORE:channel_for channel for biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/uberon/core#channel_for channel_for carries GO:0051991 UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051991 EC:2.4.1.227|MetaCyc:NACGLCTRANS-RXN|RHEA:31227 Catalysis of the reaction: N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol + UDP-N-acetyl-D-glucosamine = N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine + UDP. GO:0036350 mannose-specific flocculation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036350 cell-cell adhesion involved in mannose-specific flocculation The non-sexual aggregation of single-celled organisms mediated by the binding of cell wall proteins on one cell to mannose residues on the other. GO:0036351 histone H2A-K13 ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036351 histone H2A ubiquitination (H2A-K13) The modification of histone H2A by addition of ubiquitin group at lysine 13 (H2A-K13) in metazoans, and at the equivalent residue in other organisms. Monoubiquitin is first attached to H2A-K13 and K63-linked ubiquitin chains are then extended from this monoubiquitin. GO:0051992 UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0051992 EC:2.7.8.13|MetaCyc:PHOSNACMURPENTATRANS-RXN|RHEA:28386 Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine + di-trans,poly-cis-undecaprenyl phosphate = UMP + N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol. GO:0036352 histone H2A-K15 ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036352 histone H2A ubiquitination (H2A-K15) The modification of histone H2A by addition of ubiquitin group at lysine 15 (H2A-K15) in metazoans, and at the equivalent residue in other organisms. Monoubiquitin is first attached to H2A-K15 and K63-linked ubiquitin chains are then extended from this monoubiquitin. GO:0036353 histone H2A-K119 monoubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036353 histone H2A monoubiquitination (H2A-K119) The modification of histone H2A by addition of a single ubiquitin group to lysine-119 (H2A- K119) in metazoans, and at the equivalent residue in other organisms. GO:0051990 (R)-2-hydroxyglutarate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051990 Reactome:R-HSA-880053|RHEA:38295|Reactome:R-HSA-880007|EC:1.1.99.39 D-2-hydroxyglutarate dehydrogenase activity Catalysis of the reaction: (R)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor. GO:2000115 regulation of maintenance of bipolar cell polarity regulating cell shape biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000115 Any process that modulates the frequency, rate or extent of maintenance of bipolar cell polarity regulating in cell shape. GO:2000116 regulation of cysteine-type endopeptidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000116 regulation of lysosomal cysteine-type endopeptidase|regulation of thiol endopeptidase activity Any process that modulates the frequency, rate or extent of cysteine-type endopeptidase activity. GO:2000117 negative regulation of cysteine-type endopeptidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000117 negative regulation of thiol endopeptidase activity|negative regulation of lysosomal cysteine-type endopeptidase Any process that stops, prevents, or reduces the frequency, rate or extent of cysteine-type endopeptidase activity. GO:2000118 regulation of sodium-dependent phosphate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000118 Any process that modulates the frequency, rate or extent of sodium-dependent phosphate transport. GO:2000119 negative regulation of sodium-dependent phosphate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000119 Any process that stops, prevents, or reduces the frequency, rate or extent of sodium-dependent phosphate transport. GO:0061310 canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061310 canonical Wnt-activated signaling pathway involved in cardiac neural crest cell differentiation involved in heart development|canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development|canonical Wnt receptor signalling pathway involved in cardiac neural crest cell differentiation involved in heart development The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in cardiac neural crest cell differentiation. GO:0036343 psychomotor behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036343 The specific behavior of an organism that combines cognitive functions and physical movement. For example, driving a car, throwing a ball, or playing a musical instrument. GO:0061311 cell surface receptor signaling pathway involved in heart development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061311 cell surface receptor linked signaling pathway involved in heart development|cell surface receptor linked signalling pathway involved in heart development Any series of molecular signals initiated by the binding of a receptor on the surface of a cell to a physiological ligand, which contributes to the progression of the heart over time. GO:0036344 platelet morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036344 Generation and organization of a platelet, a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation. GO:0061312 BMP signaling pathway involved in heart development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061312 BMP signalling pathway involved in heart development A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the progression of the heart over time. GO:0036345 platelet maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036345 A developmental process, independent of morphogenetic (shape) change, that is required for a platelet to attain its fully functional state. A platelet is a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation. GO:0036346 cellular response to L-cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036346 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-cysteine stimulus. L-cysteine is an optically active form of cysteine having L-configuration. GO:2000110 negative regulation of macrophage apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000110 negative regulation of AICD|negative regulation of activation-induced cell death|negative regulation of macrophage apoptosis Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage apoptotic process. GO:0061313 fibroblast growth factor receptor signaling pathway involved in heart development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061313 fibroblast growth factor receptor signalling pathway involved in heart development The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands and contributing to the progression of the heart over time. GO:0061314 Notch signaling involved in heart development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061314 Notch signalling involved in heart development The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell and contributing to the progression of the heart over time. GO:0036347 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0036347 GO:2000111 positive regulation of macrophage apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000111 positive regulation of activation-induced cell death|positive regulation of AICD|positive regulation of macrophage apoptosis Any process that activates or increases the frequency, rate or extent of macrophage apoptotic process. GO:0036348 hydantoin racemase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036348 EC:5.1.99.5|MetaCyc:RXN-9781|RHEA:46624|KEGG_REACTION:R09704 Catalysis of the reaction: D-5-monosubstituted hydantoin = L-5-monosubstituted hydantoin. GO:0061315 canonical Wnt signaling pathway involved in positive regulation of cardiac muscle cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061315 canonical Wnt receptor signalling pathway involved in positive regulation of cardiac muscle cell proliferation|canonical Wnt-activated signaling pathway involved in positive regulation of cardiac muscle cell proliferation|canonical Wnt receptor signaling pathway involved in positive regulation of cardiac muscle cell proliferation The canonical Wnt signaling pathway that contributes to an expansion of the population of cardiac muscle cells. GO:2000112 regulation of cellular macromolecule biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000112 regulation of cellular macromolecule anabolism|regulation of cellular biopolymer biosynthetic process|regulation of cellular macromolecule synthesis|regulation of cellular macromolecule formation|regulation of cellular macromolecule biosynthesis Any process that modulates the frequency, rate or extent of cellular macromolecule biosynthetic process. GO:2000113 negative regulation of cellular macromolecule biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000113 negative regulation of cellular macromolecule biosynthesis|negative regulation of cellular macromolecule anabolism|negative regulation of cellular biopolymer biosynthetic process|negative regulation of cellular macromolecule synthesis|negative regulation of cellular macromolecule formation Any process that stops, prevents, or reduces the frequency, rate or extent of cellular macromolecule biosynthetic process. GO:0036349 galactose-specific flocculation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036349 cell-cell adhesion involved in galactose-specific flocculation The non-sexual aggregation of single-celled organisms mediated by the binding of cell wall proteins on one cell to galactose residues on the other. GO:0061316 canonical Wnt signaling pathway involved in heart development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061316 canonical Wnt receptor signalling pathway involved in heart development|canonical Wnt-activated signaling pathway involved in heart development|canonical Wnt receptor signaling pathway involved in heart development The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the heart over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes. GO:0061317 canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061317 canonical Wnt-activated signaling pathway involved in cardiac muscle cell fate commitment|canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin and contributing to cardiac muscle cell fate commitment. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes. GO:2000114 regulation of establishment of cell polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000114 regulation of cell polarization|regulation of bud site selection/establishment of cell polarity Any process that modulates the frequency, rate or extent of establishment of cell polarity. GO:0061318 renal filtration cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061318 The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a renal filtration cell. Renal filtration cells are specialized cells of the renal system that filter fluids by charge, size or both. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. GO:0061319 nephrocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061319 The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a nephrocyte. A nephrocyte is an insect renal cell that filters hemolymph. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. GO:0036340 chitin-based cuticle sclerotization by biomineralization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036340 chitin-based cuticle hardening by biomineralisation The process of hardening a chitin-based cuticle by mineral incorporation. For example, the cuticle of crustaceans is hardened by the incorporation of calcium carbonate. GO:0036341 chitin-based cuticle sclerotization by protein cross-linking biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036341 chitin-based cuticle sclerotization by protein cross-linking and cuticle tanning The process of hardening of a chitin-based cuticle by protein cross-linking, and the incorporation of phenolic precursors. This mechanism of cuticle hardening occurs in insects and is usually accompanied by darkening of the cuticle. GO:0036342 post-anal tail morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036342 The process in which a post-anal tail is generated and organized. A post-anal tail is a muscular region of the body that extends posterior to the anus. The post-anal tail may aid locomotion and balance. GO:1901109 granaticin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901109 granaticin biosynthesis|granaticin anabolism|granaticin synthesis|granaticin formation The chemical reactions and pathways resulting in the formation of granaticin. GO:1901107 granaticin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901107 granaticin metabolism The chemical reactions and pathways involving granaticin. GO:1901108 granaticin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901108 granaticin catabolism|granaticin degradation|granaticin breakdown The chemical reactions and pathways resulting in the breakdown of granaticin. GO:2000126 negative regulation of octopamine or tyramine signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000126 negative regulation of octopamine/tyramine signaling pathway|negative regulation of octopamine or tyramine signalling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of octopamine or tyramine signaling pathway. GO:1901105 tetracenomycin C catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901105 tetracenomycin C degradation|tetracenomycin C breakdown|tetracenomycin C catabolism The chemical reactions and pathways resulting in the breakdown of tetracenomycin C. GO:1901106 tetracenomycin C biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901106 tetracenomycin C biosynthesis|tetracenomycin C anabolism|tetracenomycin C synthesis|tetracenomycin C formation The chemical reactions and pathways resulting in the formation of tetracenomycin C. GO:2000127 positive regulation of octopamine or tyramine signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000127 positive regulation of octopamine or tyramine signalling pathway|positive regulation of octopamine/tyramine signaling pathway Any process that activates or increases the frequency, rate or extent of octopamine or tyramine signaling pathway. GO:1901103 gramicidin S biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901103 gramicidin S anabolism|gramicidin S synthesis|gramicidin S formation|gramicidin S biosynthesis The chemical reactions and pathways resulting in the formation of gramicidin S. GO:2000128 regulation of octopamine signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000128 regulation of octopamine signalling pathway Any process that modulates the frequency, rate or extent of octopamine signaling pathway. GO:1901104 tetracenomycin C metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901104 tetracenomycin C metabolism The chemical reactions and pathways involving tetracenomycin C. GO:2000129 negative regulation of octopamine signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000129 negative regulation of octopamine signalling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of octopamine signaling pathway. GO:1901101 gramicidin S metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901101 gramicidin S metabolism The chemical reactions and pathways involving gramicidin S. GO:1901102 gramicidin S catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901102 gramicidin S catabolism|gramicidin S degradation|gramicidin S breakdown The chemical reactions and pathways resulting in the breakdown of gramicidin S. GO:0061340 establishment or maintenance of monopolar cell polarity regulating cell shape biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061340 Any cellular process that results in the specification, formation or maintenance of a monopolar intracellular organization or cell growth patterns that regulate the shape of a cell. GO:0061341 non-canonical Wnt signaling pathway involved in heart development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061341 non-canonical Wnt receptor signalling pathway involved in heart development|non-canonical Wnt receptor signaling pathway involved in heart development|non-canonical Wnt-activated signaling pathway involved in heart development The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin and contributing to the progression of the heart over time. GO:0061342 regulation of cell adhesion involved in heart morphogenesis by non-canonical Wnt signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061342 regulation of cell adhesion involved in heart morphogenesis by non-canonical Wnt signalling pathway Any process that decreased the extent of cell adhesion that contributes to the shaping of the heart. GO:0036332 placental growth factor-activated receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036332 PlGF receptor activity|placental growth factor receptor activity|PlGF-activated receptor activity Combining with placental growth factor (PlGF) and transmitting the signal across the plasma membrane to initiate a change in cell activity. GO:0061343 cell adhesion involved in heart morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061343 The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart. GO:0036333 hepatocyte homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036333 Any biological process involved in the maintenance of the steady-state number of hepatocytes within a population of cells. Hepatocytes are specialized epithelial cells of the liver that are organized into interconnected plates called lobules. GO:0061344 regulation of cell adhesion involved in heart morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061344 Any process that modulates the extent of cell adhesion contributing to the shaping of the heart. GO:2000120 positive regulation of sodium-dependent phosphate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000120 Any process that activates or increases the frequency, rate or extent of sodium-dependent phosphate transport. GO:0036334 epidermal stem cell homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036334 Any biological process involved in the maintenance of the steady-state number of epidermal stem cells within a population of cells. GO:0061345 planar cell polarity pathway involved in cardiac muscle cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061345 The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin and contributing to a cardioblast being committed to a cardiac muscle cell fate. GO:0061346 planar cell polarity pathway involved in heart morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061346 The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the heart. GO:0036335 intestinal stem cell homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036335 Any biological process involved in the maintenance of the steady-state number of intestinal stem cells within a population of cells. GO:2000121 regulation of removal of superoxide radicals biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000121 regulation of removal of oxygen free radicals|regulation of removal of O2- Any process that modulates the frequency, rate or extent of removal of superoxide radicals. GO:0061347 planar cell polarity pathway involved in outflow tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061347 The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the outflow tract. GO:0036336 dendritic cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036336 The movement of a dendritic cell within or between different tissues and organs of the body. GO:2000122 negative regulation of stomatal complex development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000122 Any process that stops, prevents, or reduces the frequency, rate or extent of stomatal complex development. GO:0061348 planar cell polarity pathway involved in ventricular septum morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061348 The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the ventricular septum. GO:0036337 Fas signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036337 FAS ligand-Fas signaling pathway|Apo-1 signaling pathway|Fas receptor signaling pathway|CD95 signaling pathway|FasL signaling pathway|FasR signaling pathway|Fas-FasL signaling pathway A series of molecular signals initiated by the binding of a ligand to the receptor Fas on the surface of the cell, and ending with regulation of a downstream cellular process, e.g. transcription. Fas is a death domain-containing member of the tumor necrosis factor receptor (TNFR) superfamily. GO:2000123 positive regulation of stomatal complex development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000123 Any process that activates or increases the frequency, rate or extent of stomatal complex development. GO:2000124 regulation of endocannabinoid signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000124 regulation of endocannabinoid signalling pathway Any process that modulates the frequency, rate or extent of endocannabinoid signaling pathway. GO:0061349 planar cell polarity pathway involved in cardiac right atrium morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061349 The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the cardiac right atrium. GO:0036338 viral membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036338 The lipid bilayer of a virion, a complete fully infectious extracellular virus particle. GO:2000125 regulation of octopamine or tyramine signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000125 regulation of octopamine or tyramine signalling pathway|regulation of octopamine/tyramine signaling pathway Any process that modulates the frequency, rate or extent of octopamine or tyramine signaling pathway. GO:0036339 lymphocyte adhesion to endothelial cell of high endothelial venule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036339 lymphocyte adhesion to high endothelial venule|lymphocyte adhesion to HEV cell The attachment of a lymphocyte to an endothelial cell of a high endothelial venule (HEV) via adhesion molecules. A HEV cell is an endothelial cell that is cuboidal, expresses leukocyte-specific receptors, and allows for passage of lymphocytes into bloodstream. CHEBI:9347 sulfoglycolithocholic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_9347 CHEBI:9349 sulfonyldimethane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_9349 GO:0036330 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0036330 GO:0036331 avascular cornea development in camera-type eye biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036331 avascular cornea development The progression of an avascular cornea over time, from its formation to the mature structure. Corneal avascularity (the absence of blood vessels in the cornea) is required for optical clarity and optimal vision. Avascular corneas are present in most animals, except Manatees. GO:1901118 cephamycin C biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901118 cephamycin C anabolism|cephamycin C synthesis|cephamycin C formation|cephamycin C biosynthesis The chemical reactions and pathways resulting in the formation of cephamycin C. GO:1901119 tobramycin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901119 tobramycin metabolism The chemical reactions and pathways involving tobramycin. GO:1901116 cephamycin C metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901116 cephamycin C metabolism The chemical reactions and pathways involving cephamycin C. GO:2000137 negative regulation of cell proliferation involved in heart morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000137 Any process that stops, prevents, or reduces the frequency, rate or extent of cell proliferation involved in heart morphogenesis. GO:0036329 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0036329 GO:1901117 cephamycin C catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901117 cephamycin C degradation|cephamycin C breakdown|cephamycin C catabolism The chemical reactions and pathways resulting in the breakdown of cephamycin C. GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000138 Any process that activates or increases the frequency, rate or extent of cell proliferation involved in heart morphogenesis. GO:1901114 erythromycin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901114 erythromycin catabolism|erythromycin degradation|erythromycin breakdown The chemical reactions and pathways resulting in the breakdown of erythromycin. GO:2000139 regulation of octopamine signaling pathway involved in response to food biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000139 regulation of octopamine signalling pathway involved in response to food Any process that modulates the frequency, rate or extent of octopamine signaling pathway involved in response to food. GO:1901115 erythromycin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901115 erythromycin formation|erythromycin biosynthesis|erythromycin anabolism|erythromycin synthesis The chemical reactions and pathways resulting in the formation of erythromycin. GO:1901112 actinorhodin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901112 actinorhodin biosynthesis|actinorhodin anabolism|actinorhodin synthesis|actinorhodin formation The chemical reactions and pathways resulting in the formation of actinorhodin. GO:1901113 erythromycin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901113 erythromycin metabolism The chemical reactions and pathways involving erythromycin. GO:1901110 actinorhodin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901110 actinorhodin metabolism The chemical reactions and pathways involving actinorhodin. GO:0061330 Malpighian tubule stellate cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061330 The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule stellate cell. A Malpighian tubule stellate cell is a specialized epithelial secretory cell that moves chloride ions and water across the tubule epithelium. GO:1901111 actinorhodin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901111 actinorhodin degradation|actinorhodin breakdown|actinorhodin catabolism The chemical reactions and pathways resulting in the breakdown of actinorhodin. GO:0061331 epithelial cell proliferation involved in Malpighian tubule morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061331 The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population and contributing to the shaping of a Malpighian tubule. GO:0061332 Malpighian tubule bud morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061332 Malpighian tubule formation The morphogenetic process in which a bud forms from the embryonic hindgut tube to form the Malpighian tubule. A bud is a protrusion that forms from the tube by localized changes in cell shape and position. GO:0036321 ghrelin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036321 pancreatic ghrelin secretion The regulated release of ghrelin from a cell. Ghrelin is a 28 amino acid hunger-stimulating peptide hormone. GO:0036322 pancreatic polypeptide secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036322 PP secretion The regulated release of pancreatic polypeptide (PP) from a cell. Pancreatic polypeptide is a 36 amino acid polypeptide secreted by islets of Langerhans cells in the pancreas. GO:0061333 renal tubule morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061333 The process in which the renal tubule is generated by specification of cell fate, through the maintenance of cell polarity, regulated cell proliferation and morphogenetic cell rearrangements, shape changes and growth. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis. GO:2000130 positive regulation of octopamine signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000130 positive regulation of octopamine signalling pathway Any process that activates or increases the frequency, rate or extent of octopamine signaling pathway. GO:1901120 tobramycin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901120 tobramycin degradation|tobramycin catabolism|tobramycin breakdown The chemical reactions and pathways resulting in the breakdown of tobramycin. GO:0061334 cell rearrangement involved in Malpighian tubule morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061334 cell migration involved in Malpighian tubule morphogenesis The movement of an epithelial cell with respect to other epithelial cells that contributes to the shaping of the Malpighian tubule. GO:0036323 vascular endothelial growth factor receptor-1 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036323 FLT1 signaling pathway|VEGFR1 signaling pathway|VEGFR-1 signaling pathway Any series of molecular signals initiated by the binding of an extracellular ligand to a vascular endothelial growth factor receptor-1 (VEGFR-1) located on the surface of the receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:2000131 regulation of tyramine signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000131 regulation of tyramine signalling pathway Any process that modulates the frequency, rate or extent of tyramine signaling pathway. GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036324 VEGFR-2 signaling pathway|FLK-1 signaling pathway|VEGFR2 signaling pathway|KDR signaling pathway Any series of molecular signals initiated by the binding of an extracellular ligand to a vascular endothelial growth factor receptor-2 (VEGFR-2) located on the surface of the receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:2000132 negative regulation of tyramine signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000132 negative regulation of tyramine signalling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of tyramine signaling pathway. GO:0061335 cell growth involved in Malpighian tubule morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061335 The growth of an epithelial cell dependent on cycles of endoreplication, where growth contributes to the shaping of the Malpighian tubule. GO:0061336 cell morphogenesis involved in Malpighian tubule morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061336 The shape change of an epithelial cell from a columnar to squamous cell morphology that contributes to the shaping of the Malpighian tubule. GO:2000133 positive regulation of tyramine signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000133 positive regulation of tyramine signalling pathway Any process that activates or increases the frequency, rate or extent of tyramine signaling pathway. GO:0036325 vascular endothelial growth factor receptor-3 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036325 VEGFR3 signaling pathway|FLT4 signaling pathway|VEGFR-3 signaling pathway Any series of molecular signals initiated by the binding of an extracellular ligand to a vascular endothelial growth factor receptor-3 (VEGFR-3) located on the surface of the receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0061337 cardiac conduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061337 Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles. GO:0036326 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0036326 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000134 Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle. GO:2000135 obsolete positive regulation of regulation of secondary heart field cardioblast proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000135 positive regulation of regulation of secondary heart field cardioblast proliferation|positive regulation of regulation of second heart field cardioblast proliferation OBSOLETE. Any process that activates or increases the frequency, rate or extent of regulation of secondary heart field cardioblast proliferation. GO:0061338 obsolete atrioventricular node impulse conduction delay biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061338 atrioventricular node impulse conduction delay OBSOLETE. A heart process that modulates the propagation of the signal that causes the heart muscle to contract. GO:0036327 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0036327 GO:0061339 establishment or maintenance of monopolar cell polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061339 Any cellular process that results in the specification, formation or maintenance of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis. GO:0036328 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0036328 GO:2000136 regulation of cell proliferation involved in heart morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000136 Any process that modulates the frequency, rate or extent of cell proliferation involved in heart morphogenesis. GO:0036320 mating-type P-factor pheromone receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036320 P-factor receptor activity|P-factor mating pheromone receptor activity Combining with the mating-type peptide pheromone P-factor and transmitting the signal across the membrane to initiate a change in cell activity. P-factor is a polypeptide of 23 residues, with the sequence Thr-Tyr-Ala-Asp-Phe-Leu-Arg-Ala-Tyr-Gln-Ser-Trp-Asn-Thr-Phe-Val-Asn-Pro-Asp-Arg-Pro-Asn-Leu, and is a peptide pheromone released by Schizosaccharomyces pombe cells of the cellular mating type Plus. GO:1901129 gentamycin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901129 gentamycin breakdown|gentamycin catabolism|gentamycin degradation The chemical reactions and pathways resulting in the breakdown of gentamycin. GO:1901127 candicidin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901127 candicidin formation|candicidin biosynthesis|candicidin anabolism|candicidin synthesis The chemical reactions and pathways resulting in the formation of candicidin. GO:0036318 peptide pheromone receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036318 Combining with a peptide pheromone, and transmitting the signal across the membrane to initiate a change in cell activity. GO:0036319 mating-type M-factor pheromone receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036319 M-factor mating pheromone receptor activity|M-factor receptor activity Combining with the mating-type peptide pheromone M-factor and transmitting the signal across the membrane to initiate a change in cell activity. M-factor is a nine-membered oligopeptide that consists of tyrosyl, threonyl, prolyl, lysyl, valyl, prolyl, tyrosyl, methionyl and methyl S-farnesylcysteinate residues joined in sequence, and is a peptide pheromone released by Schizosaccharomyces pombe cells of the cellular mating type Minus. GO:1901128 gentamycin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901128 gentamycin metabolism The chemical reactions and pathways involving gentamycin. GO:1901125 candicidin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901125 candicidin metabolism The chemical reactions and pathways involving candicidin. GO:1901126 candicidin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901126 candicidin degradation|candicidin breakdown|candicidin catabolism The chemical reactions and pathways resulting in the breakdown of candicidin. GO:0061360 optic chiasma development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061360 optic chiasm development The developmental process pertaining to the progression of the optic chiasm from its initial formation to the mature structure. The process begins when the pathfinding of the axons of the developing optic nerve cause some axons to cross at the midline of the brain and ends when the axons are mature. GO:1901123 bacitracin A catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901123 bacitracin A degradation|bacitracin A breakdown|bacitracin A catabolism The chemical reactions and pathways resulting in the breakdown of bacitracin A. GO:0061361 positive regulation of maintenance of bipolar cell polarity regulating cell shape biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061361 Any process that increases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape. GO:1901124 bacitracin A biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901124 bacitracin A synthesis|bacitracin A formation|bacitracin A anabolism|bacitracin A biosynthesis The chemical reactions and pathways resulting in the formation of bacitracin A. GO:0061362 negative regulation of maintenance of bipolar cell polarity regulating cell shape biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061362 Any process that decreases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape. GO:1901121 tobramycin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901121 tobramycin anabolism|tobramycin synthesis|tobramycin formation|tobramycin biosynthesis The chemical reactions and pathways resulting in the formation of tobramycin. GO:0061363 negative regulation of progesterone biosynthesis involved in luteolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061363 functional luteolysis Any process that decreases the rate, frequency or extent of the biosynthesis of progesterone biosynthesis that contributes to luteolysis. GO:1901122 bacitracin A metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901122 bacitracin A metabolism The chemical reactions and pathways involving bacitracin A. GO:0061364 apoptotic process involved in luteolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061364 structural luteolysis|apoptosis involved in luteolysis The apoptotic process that contributes to luteolysis. GO:1901130 gentamycin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901130 gentamycin anabolism|gentamycin synthesis|gentamycin formation|gentamycin biosynthesis The chemical reactions and pathways resulting in the formation of gentamycin. GO:0061365 positive regulation of triglyceride lipase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061365 positive regulation of TAG activity Any process that increases the activity of triglyceride lipase. GO:0036310 annealing helicase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036310 nucleoside-triphosphatase activity involved in DNA annealing|ATP-dependent DNA annealing activity|annealing activity Catalysis of the ATP-dependent rewinding of single-stranded DNA (ssDNA) to reform base pairs between strands. Often acts on ssDNA bubbles bound by replication protein A (RPA). GO:0036311 chitin disaccharide deacetylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036311 chitin oligosaccharide amidohydrolase activity|chitobiose amidohydrolase activity|chitin oligosaccharide deacetylase activity Catalysis of the reaction: 2-(acetylamino)-4-O-[2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl]-2-deoxy-beta-D-glucopyranose + H2O = 2-(acetylamino)-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-beta-D-glucopyranose + acetate. GO:1901131 kanamycin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901131 kanamycin metabolism The chemical reactions and pathways involving kanamycin. GO:0061366 behavioral response to chemical pain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061366 Any process that results in a change in the behaviour of an organism as a result of a chemical pain stimulus. GO:0061367 behavioral response to acetic acid induced pain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061367 Any process that results in a change in the behaviour of an organism as a result of an acetic acid pain stimulus. GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036312 p85 binding|PI3K regulatory subunit binding Interacting selectively and non-covalently with a regulatory subunit of phosphatidylinositol 3-kinase. The regulatory subunit associates with the catalytic subunit to regulate both its activity and subcellular location. GO:0061368 behavioral response to formalin induced pain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061368 Any process that results in a change in the behaviour of an organism as a result of a formalin pain stimulus. GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036313 p110 binding|PI3K catalytic subunit binding Interacting selectively and non-covalently with the catalytic subunit of a phosphatidylinositol 3-kinase. The catalytic subunit catalyzes the addition of a phosphate group to an inositol lipid at the 3' position of the inositol ring. GO:0061369 negative regulation of testicular blood vessel morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061369 negative regulation of testicular vasculature morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis in the testicle. GO:0036314 response to sterol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036314 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sterol stimulus. GO:0036315 cellular response to sterol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036315 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sterol stimulus. GO:0036316 SREBP-SCAP complex retention in endoplasmic reticulum biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036316 Any process in which the SREBP-SCAP complex is maintained in the endoplasmic reticulum and prevented from moving elsewhere. The SREBP-SCAP complex is formed by the association of sterol regulatory element binding protein (SREBP) and SREBP-cleavage-activating protein (SCAP). In the absence of sterols, the SREBP-SCAP complex is packaged into COPII vesicles and travels to the Golgi apparatus to be processed. In the presence of sterols, the complex binds ER-resident proteins such as INSIG, which retain the complex in the ER. GO:0036317 tyrosyl-RNA phosphodiesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036317 unlinkase activity|VPg unlinkase activity|uridylylpolynucleotide-(5' P->O)- tyrosine phosphodiesterase activity|Y-pUpN PDE activity Catalysis of the hydrolysis of a 5' tyrosyl-RNA phosphodiester bond between a protein and RNA. In picornaviruses, this covalent bond connects VPg, a viral-encoded protein essential for RNA replication, to the 5' end of all nascent picornavirus genomes; it is cleaved from viral RNA prior to its engaging in protein synthesis. GO:0036307 23S rRNA (adenine(2030)-N(6))-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036307 Catalysis of the reaction: S-adenosyl-L-methionine + adenine(2030) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(2030) in 23S rRNA. GO:1901138 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1901138 GO:0036308 16S rRNA (guanine(1516)-N(2))-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036308 Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(1516) in 16S rRNA = N(2)-methylguanosine(1516) in 16S rRNA + S-adenosyl-L-homocysteine. GO:1901139 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1901139 GO:0036309 protein localization to M-band biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036309 protein localization to M line|cellular protein localization to M-band|protein localization to mesophragma|protein localization to M disc Any process in which a protein is transported to, and/or maintained in, the M band. The M band is the midline of aligned thick filaments in a sarcomere. GO:1901136 carbohydrate derivative catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901136 carbohydrate derivative degradation|carbohydrate derivative catabolism|carbohydrate derivative breakdown The chemical reactions and pathways resulting in the breakdown of carbohydrate derivative. GO:1901137 carbohydrate derivative biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901137 carbohydrate derivative anabolism|carbohydrate derivative synthesis|carbohydrate derivative formation|carbohydrate derivative biosynthesis The chemical reactions and pathways resulting in the formation of carbohydrate derivative. GO:0061350 planar cell polarity pathway involved in cardiac muscle tissue morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061350 The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the cardiac muscle tissue. GO:1901134 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1901134 GO:0061351 neural precursor cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061351 The multiplication or reproduction of neural precursor cells, resulting in the expansion of a cell population. A neural precursor cell is either a nervous system stem cell or a nervous system progenitor cell. GO:1901135 carbohydrate derivative metabolic process biolink:BiologicalProcess go-plus goslim_mouse|goslim_agr http://purl.obolibrary.org/obo/GO_1901135 carbohydrate derivative metabolism The chemical reactions and pathways involving carbohydrate derivative. GO:0061352 cell chemotaxis involved in Malpighian tubule morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061352 The directed movement of the outgrowing Malpighian tubule guided by specific chemical cues/signals. Movement may be towards a guidance cue (positive chemotaxis) or away from it (negative chemotaxis). Guidance contributes to the final positioning of the tubule. GO:1901132 kanamycin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901132 kanamycin catabolism|kanamycin degradation|kanamycin breakdown The chemical reactions and pathways resulting in the breakdown of kanamycin. GO:1901133 kanamycin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901133 kanamycin anabolism|kanamycin synthesis|kanamycin formation|kanamycin biosynthesis The chemical reactions and pathways resulting in the formation of kanamycin. GO:0061353 BMP signaling pathway involved in Malpighian tubule cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061353 bone morphogenic protein receptor signalling pathway involved in Malpighian tubule cell chemotaxis A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the directed movement of a Malpighian tubule cell toward a stimulus, thereby contributing to the shaping of the tubule. GO:1901141 regulation of lignin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901141 regulation of lignin anabolism|regulation of lignin synthesis|regulation of lignin biosynthesis|regulation of lignin formation Any process that modulates the frequency, rate or extent of lignin biosynthetic process. GO:0061354 planar cell polarity pathway involved in pericardium morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061354 The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the pericardium. GO:1901142 insulin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901142 insulin metabolism The chemical reactions and pathways involving insulin. GO:0061355 Wnt protein secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061355 The controlled release of a Wnt protein from a cell. GO:0036300 B cell receptor internalization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036300 BCR receptor internalization|B cell receptor uptake of antigen|BCR endocytosis A receptor-mediated endocytosis process that results in the movement of a B cell receptor from the plasma membrane to the inside of the cell. GO:0036301 macrophage colony-stimulating factor production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0036301 M-CSF production The appearance of macrophage colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0061356 regulation of Wnt protein secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061356 Any process that modulates the frequency, rate or extent of the controlled release of a Wnt protein from a cell. GO:0036302 atrioventricular canal development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036302 The progression of the atrioventricular canal over time, from its formation to the mature structure. The atrioventricular canal is the part of the heart connecting the atrium to the cardiac ventricle. GO:0061357 positive regulation of Wnt protein secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061357 Any process that activates or increases the frequency, rate or extent of the controlled release of a Wnt protein from a cell. GO:1901140 p-coumaryl alcohol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901140 4-hydroxycinnamyl alcohol transport The directed movement of a p-coumaryl alcohol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:131487 1,2-diacyl-3-(alpha-D-6-sulfoquinovosyl)-sn-glycerol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131487 GO:0036303 lymph vessel morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036303 The process in which the anatomical structures of lymph vessels are generated and organized. The lymph vessel is the vasculature carrying lymph. GO:0061358 negative regulation of Wnt protein secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061358 Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a Wnt protein from a cell. GO:0061359 regulation of Wnt signaling pathway by Wnt protein secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061359 regulation of Wnt receptor signaling pathway by Wnt protein secretion|regulation of Wnt receptor signalling pathway by Wnt protein secretion|regulation of Wnt-activated signaling pathway by Wnt protein secretion Any process that modulates the frequency, rate or extent of the activity of the Wnt signaling pathway by the controlled release of a Wnt protein from a cell. GO:0036304 umbilical cord morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036304 The process in which the anatomical structures of the umbilical cord are generated and organized. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta. GO:0036305 ameloblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036305 The process in which a relatively unspecialized cell acquires specialized features of an ameloblast, a cylindrical epithelial cell in the innermost layer of the enamel organ. GO:0036306 embryonic heart tube elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036306 The developmental growth that results in the increase in length of the embryonic heart tube. The embryonic heart tube is an epithelial tube that will give rise to the mature heart. GO:1901149 salicylic acid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901149 salicylic acid receptor Interacting selectively and non-covalently with salicylic acid. GO:0061380 superior colliculus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061380 The process whose specific outcome is the progression of the superior colliculus over time, from its formation to the mature structure. The superior colliculus is also known as the optic tectum or simply tectum and is a paired structure that forms a major component of the vertebrate midbrain. GO:0061381 cell migration in diencephalon biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061381 The orderly movement of a cell that will reside in the diencephalon. GO:1901147 mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901147 Any mesenchymal cell apoptotic process that is involved in metanephric nephron morphogenesis. GO:0061382 Malpighian tubule tip cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061382 The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule tip cell. A Malpighian tubule tip cell is a mitogenic signaling cell that controls the proliferation of its neighboring cells. GO:1901148 gene expression involved in extracellular matrix organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901148 extracellular matrix protein production|expression of extracellular matrix proteins Any gene expression that is involved in extracellular matrix organization. Gene expression includes both transcription to produce an RNA transcript, and the translation of that mRNA into protein. Protein maturation is included in gene expression when required to form an active form of a product from an inactive precursor form. GO:1901145 mesenchymal cell apoptotic process involved in nephron morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901145 Any mesenchymal cell apoptotic process that is involved in nephron morphogenesis. GO:0061383 trabecula morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061383 The process of shaping a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue. GO:0061384 heart trabecula morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061384 The process of shaping a trabecula in the heart. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue. GO:1901146 mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901146 Any mesenchymal cell apoptotic process that is involved in mesonephric nephron morphogenesis. GO:1901143 insulin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901143 insulin degradation|insulin breakdown|insulin catabolism The chemical reactions and pathways resulting in the breakdown of insulin. GO:0061385 fibroblast proliferation involved in heart morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061385 The multiplication or reproduction of fibroblasts, resulting in the expansion of a fibroblast population that contributes to the shaping of the heart. GO:1901144 obsolete insulin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901144 insulin formation|insulin biosynthetic process|insulin anabolism|insulin biosynthesis|insulin synthesis OBSOLETE. The chemical reactions and pathways resulting in the formation of insulin. GO:0061386 closure of optic fissure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061386 closure or choriod fissure The closure of the temporary ventral gap in the optic cup that contributes to its shaping. GO:1901152 vistamycin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901152 vistamycin anabolism|vistamycin synthesis|vistamycin formation|vistamycin biosynthesis|ribostamycin anabolism|ribostamycin synthesis|ribostamycin formation|ribostamycin biosynthetic process|ribostamycin biosynthesis The chemical reactions and pathways resulting in the formation of vistamycin. GO:0061387 regulation of extent of cell growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061387 Any process that modulates the extent of cell growth. CHEBI:131450 2,6-dihydroxybenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131450 GO:0061388 regulation of rate of cell growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061388 Any process that modulates the rate of cell growth. GO:1901153 paromomycin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901153 paromomycin metabolism The chemical reactions and pathways involving paromomycin. GO:1901150 vistamycin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901150 ribostamycin metabolic process|vistamycin metabolism|ribostamycin metabolism The chemical reactions and pathways involving vistamycin. GO:0061389 regulation of direction of cell growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061389 Any process that modulates the direction of cell growth. GO:1901151 vistamycin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901151 ribostamycin degradation|ribostamycin breakdown|vistamycin catabolism|ribostamycin catabolic process|vistamycin degradation|ribostamycin catabolism|vistamycin breakdown The chemical reactions and pathways resulting in the breakdown of vistamycin. GO:1901158 neomycin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901158 neomycin biosynthesis|neomycin anabolism|neomycin synthesis|neomycin formation The chemical reactions and pathways resulting in the formation of neomycin. GO:0061370 testosterone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061370 The chemical reactions and pathways resulting in the formation of testosterone, an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4 C-5. GO:0061371 determination of heart left/right asymmetry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061371 determination of cardiac left/right asymmetry Determination of the asymmetric location of the heart with respect to the left and right halves of the organism. GO:1901159 xylulose 5-phosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901159 xylulose 5-phosphate biosynthesis|xylulose 5-phosphate anabolism|xylulose 5-phosphate synthesis|xylulose 5-phosphate formation The chemical reactions and pathways resulting in the formation of xylulose 5-phosphate. GO:1901156 neomycin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901156 neomycin metabolism The chemical reactions and pathways involving neomycin. GO:0061372 activin receptor signaling pathway involved in heart jogging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061372 activin receptor signalling pathway involved in heart jogging A series of molecular signals initiated by the binding of a member of the activin family to a receptor on the surface of a target cell, and contributing to the process of heart jogging. GO:1901157 neomycin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901157 neomycin catabolism|neomycin degradation|neomycin breakdown The chemical reactions and pathways resulting in the breakdown of neomycin. GO:0061373 mammillary axonal complex development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061373 The progression of the mammillary axonal complex over time, from its formation to the mature structure. The mammillary axonal complex is formed by the axons from the lateral, medial mammillary and the dorsal premammillary nuclei which share a branching pattern. Every neuron gives off one axonal stem that bifurcates into 2 branches. One of the branches is directed dorsally to the thalamus and another caudally to the midbrain. GO:0061374 mammillothalamic axonal tract development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061374 The progression of the mammillothalamic axonal tract, from its formation to the mature structure. The mammillothalamic tract is the collection of axons that connects the two major subdivisions of the diencephalon (hypothalamus and thalamus) and closes the diencephalic circuit. GO:1901154 paromomycin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901154 paromomycin catabolism|paromomycin degradation|paromomycin breakdown The chemical reactions and pathways resulting in the breakdown of paromomycin. GO:1901155 paromomycin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901155 paromomycin anabolism|paromomycin biosynthesis|paromomycin synthesis|paromomycin formation The chemical reactions and pathways resulting in the formation of paromomycin. GO:0061375 mammillotectal axonal tract development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061375 The progression of the mammillotectal tract over time, from its formation to the mature structure. The mammillotectal tract is the collection of axons that connects the ventral diencephalon to the superior colliculus. GO:1901163 regulation of trophoblast cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901163 Any process that modulates the frequency, rate or extent of trophoblast cell migration. GO:0061376 mammillotegmental axonal tract development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061376 The process in which the mammillotegmental tract progresses over time, from its formation to the mature structure. The mammillotegmental tract is the collection of axons that connects the ventral diencephalon to the tegmentum and pons. GO:0061377 mammary gland lobule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061377 The progression of the mammary gland lobule over time, from its formation to the mature structure. A mammary gland lobule is a small rounded projection of the mammary gland. GO:1901164 negative regulation of trophoblast cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901164 downregulation of trophoblast cell migration|down regulation of trophoblast cell migration|inhibition of trophoblast cell migration|down-regulation of trophoblast cell migration Any process that stops, prevents or reduces the frequency, rate or extent of trophoblast cell migration. GO:1901161 primary amino compound catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901161 primary amino compound degradation|primary amino compound breakdown|primary amino compound catabolism The chemical reactions and pathways resulting in the breakdown of primary amino compound. GO:0061378 corpora quadrigemina development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061378 The progression of the corpora quadrigemina over time, from its formation to the mature structure. The corpora quadrigemina is a part of the midbrain that is made up of the superior and inferior colliculi. GO:0061379 inferior colliculus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061379 The process whose specific outcome is the progression of the inferior colliculus over time, from its formation to the mature structure. The inferior colliculus (IC) (Latin, lower hill) is the principal midbrain nucleus of the auditory pathway and receives input from several more peripheral brainstem nuclei in the auditory pathway, as well as inputs from the auditory cortex. The inferior colliculus has three subdivisions: the central nucleus (CIC), a dorsal cortex (DCIC) by which it is surrounded, and an external cortex (ICX) which is located laterally. GO:1901162 primary amino compound biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901162 primary amino compound anabolism|primary amino compound biosynthesis|primary amino compound synthesis|primary amino compound formation The chemical reactions and pathways resulting in the formation of primary amino compound. GO:1901160 primary amino compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901160 primary amino compound metabolism The chemical reactions and pathways involving primary amino compound. CHEBI:9398 tamsulosin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_9398 CHEBI:26945 thiamine phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26945 GO:0051911 Methanosarcina-phenazine hydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051911 EC:1.12.98.3|MetaCyc:RXN-7733|RHEA:24436 methylviologen-reducing hydrogenase activity|methanophenazine hydrogenase activity|coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase activity|hydrogen:2-(2,3-dihydropentaprenyloxy)phenazine oxidoreductase activity Catalysis of the reaction: H2 + 2-(2,3-dihydropentaprenyloxy)phenazine = 2-dihydropentaprenyloxyphenazine. GO:0051912 CoB--CoM heterodisulfide reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051912 EC:1.8.98.1|MetaCyc:1.8.98.1-RXN|RHEA:18085 soluble heterodisulfide reductase activity|coenzyme B--coenzyme M heterodisulfide reductase activity|CoB-CoM heterodisulfide reductase activity|heterodisulfide reductase activity|coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase activity|coenzyme B:coenzyme M:methanophenazine oxidoreductase activity Catalysis of the reaction: coenzyme B + coenzyme M + methanophenazine = N-{7-[(2-sulfoethyl)dithio]heptanoyl}-3-O-phospho-L-threonine + dihydromethanophenazine. GO:0051910 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051910 GO:0051915 induction of synaptic plasticity by chemical substance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051915 induction of synaptic plasticity by drug|activation of synaptic plasticity by drug|activation of synaptic plasticity by chemical substance The process in which a chemical substance activates synaptic plasticity, the ability of synapses to change as circumstances require. GO:0051916 granulocyte colony-stimulating factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051916 G-CSF binding|granulocyte colony stimulating factor binding Interacting selectively and non-covalently with granulocyte colony-stimulating factor, G-CSF. GO:0051913 regulation of synaptic plasticity by chemical substance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051913 regulation of synaptic plasticity by drug The process in which a chemical substance modulates synaptic plasticity, the ability of synapses to change as circumstances require. CHEBI:85241 1-monooctanoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85241 GO:0051914 positive regulation of synaptic plasticity by chemical substance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051914 up-regulation of synaptic plasticity by chemical substance|upregulation of synaptic plasticity by chemical substance|positive regulation of synaptic plasticity by drug|up regulation of synaptic plasticity by chemical substance|activation of synaptic plasticity by chemical substance|stimulation of synaptic plasticity by chemical substance The process in which a chemical substance increases synaptic plasticity, the ability of synapses to change as circumstances require. GO:0051919 positive regulation of fibrinolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051919 up-regulation of fibrinolysis|activation of fibrinolysis|up regulation of fibrinolysis|upregulation of fibrinolysis|stimulation of fibrinolysis Any process that activates, maintains or increases the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots. GO:0051917 regulation of fibrinolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051917 Any process that modulates the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots. GO:0051918 negative regulation of fibrinolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051918 down-regulation of fibrinolysis|downregulation of fibrinolysis|down regulation of fibrinolysis|inhibition of fibrinolysis Any process that stops, prevents, or reduces the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots. GO:2000184 positive regulation of progesterone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000184 positive regulation of progesterone synthesis|positive regulation of progesterone formation|positive regulation of progesterone biosynthesis|positive regulation of progesterone anabolism Any process that activates or increases the frequency, rate or extent of progesterone biosynthetic process. GO:2000185 regulation of phosphate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000185 regulation of phosphate membrane transport Any process that modulates the frequency, rate or extent of phosphate transmembrane transport. GO:2000186 negative regulation of phosphate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000186 negative regulation of phosphate membrane transport Any process that stops, prevents, or reduces the frequency, rate or extent of phosphate transmembrane transport. CHEBI:61278 scutellarin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61278 GO:2000187 positive regulation of phosphate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000187 positive regulation of phosphate membrane transport Any process that activates or increases the frequency, rate or extent of phosphate transmembrane transport. GO:2000188 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2000188 GO:2000189 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2000189 GO:2000180 negative regulation of androgen biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000180 negative regulation of androgen biosynthesis|negative regulation of androgen anabolism|negative regulation of androgen synthesis|negative regulation of androgen formation Any process that stops, prevents, or reduces the frequency, rate or extent of androgen biosynthetic process. GO:2000181 negative regulation of blood vessel morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000181 Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis. CHEBI:26948 thiamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26948 GO:2000182 regulation of progesterone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000182 regulation of progesterone anabolism|regulation of progesterone synthesis|regulation of progesterone formation|regulation of progesterone biosynthesis Any process that modulates the frequency, rate or extent of progesterone biosynthetic process. GO:2000183 negative regulation of progesterone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000183 negative regulation of progesterone formation|negative regulation of progesterone anabolism|negative regulation of progesterone biosynthesis|negative regulation of progesterone synthesis Any process that stops, prevents, or reduces the frequency, rate or extent of progesterone biosynthetic process. CHEBI:26955 thiocyanates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26955 GO:0051922 cholesterol sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051922 EC:2.8.2.- Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + cholesterol = adenosine 3',5'-bisphosphate + cholesterol sulfate. CHEBI:61280 5-nitroanthranilic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61280 GO:0051923 sulfation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051923 phase II metabolism|sulfur addition|sulphur addition|sulfonation|sulphation The addition of a sulfate group to a molecule. GO:0051920 peroxiredoxin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051920 Reactome:R-HSA-1500804|MetaCyc:1.11.1.15-RXN|EC:1.11.1.15|Reactome:R-HSA-1222431|RHEA:10008|Reactome:R-HSA-1222755 AhpC activity|thiol-containing-reductant:hydroperoxide oxidoreductase activity|PRDX activity|Prx activity|alkyl hydroperoxide reductase C22 activity Catalysis of the reaction: 2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH. CHEBI:26952 thioacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26952 GO:0051921 adenosylcobyric acid synthase (glutamine-hydrolyzing) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051921 EC:6.3.5.10|MetaCyc:R345-RXN|RHEA:23256|KEGG_REACTION:R05225 Ado-cobyric acid synthase [glutamine hydrolyzing] activity|CobQ activity|cobyric acid synthase activity|adenosylcobyrinic-acid-a,c-diamide:L-glutamine amido-ligase (ADP-forming)|5'-deoxy-5'-adenosylcobyrinic-acid-a,c-diamide:L-glutamine amido-ligase activity|adenosylcobyric acid synthase (glutamine-hydrolysing) activity Catalysis of the reaction: 4 L-glutamine + adenosylcob(III)yrinate a,c-diamide + 4 ATP + 4 H(2)O = 4 L-glutamate + adenosylcobyrate + 4 ADP + 8 H(+) + 4 phosphate. CHEBI:26953 thioadenosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26953 GO:0051926 negative regulation of calcium ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051926 down regulation of calcium ion transport|downregulation of calcium ion transport|down-regulation of calcium ion transport|inhibition of calcium ion transport|negative regulation of calcium transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:61283 baicalin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61283 GO:0051927 obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051927 inhibition of calcium ion transport via voltage gated calcium channel|negative regulation of calcium ion transport via voltage-gated calcium channel activity|negative regulation of calcium transport via voltage gated calcium channel|down regulation of calcium ion transport via voltage gated calcium channel|downregulation of calcium ion transport via voltage gated calcium channel|down-regulation of calcium ion transport via voltage gated calcium channel OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions via a voltage-gated calcium channel. CHEBI:61284 scutellarin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61284 GO:0051924 regulation of calcium ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051924 regulation of calcium transport Any process that modulates the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:61281 5-nitrosalicylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61281 CHEBI:85230 N-arachidonoyl-sn-glycero-3-phosphoethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85230 GO:0051925 obsolete regulation of calcium ion transport via voltage-gated calcium channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051925 regulation of calcium transport via voltage-gated calcium channel|regulation of calcium ion transport via voltage-gated calcium channel activity OBSOLETE. Any process that modulates the frequency, rate or extent of the directed movement of calcium ions via a voltage-gated calcium channel. CHEBI:61282 wogonin 7-O-beta-D-glucuronide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61282 CHEBI:85231 1-(9Z-octadecenyl)-2-arachidonoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85231 CHEBI:85232 prostaglandin D2 1-glyceryl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85232 CHEBI:61287 (S)-2-O-sulfonatolactate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61287 CHEBI:61285 wogonin 7-O-beta-D-glucuronate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61285 GO:0051928 positive regulation of calcium ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051928 up regulation of calcium ion transport|activation of calcium ion transport|stimulation of calcium ion transport|positive regulation of calcium transport|up-regulation of calcium ion transport|upregulation of calcium ion transport Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:85234 human blood serum metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85234 GO:0051929 obsolete positive regulation of calcium ion transport via voltage-gated calcium channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051929 up-regulation of calcium ion transport via voltage gated calcium channel|positive regulation of calcium ion transport via voltage-gated calcium channel activity|upregulation of calcium ion transport via voltage gated calcium channel|up regulation of calcium ion transport via voltage gated calcium channel|activation of calcium ion transport via voltage gated calcium channel|stimulation of calcium ion transport via voltage gated calcium channel|positive regulation of calcium transport via voltage gated calcium channel OBSOLETE. Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions via the activity of voltage-gated calcium channels. CHEBI:61286 dolichol-linked oligosaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61286 CHEBI:85236 15-deoxy-Delta(12,14)-prostaglandin J2(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85236 GO:2000195 negative regulation of female gonad development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000195 negative regulation of ovary development|negative regulation of ovarian development Any process that stops, prevents, or reduces the frequency, rate or extent of female gonad development. GO:2000196 positive regulation of female gonad development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000196 positive regulation of ovary development|positive regulation of ovarian development Any process that activates or increases the frequency, rate or extent of female gonad development. CHEBI:85237 1-myristoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85237 GO:2000197 regulation of ribonucleoprotein complex localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000197 regulation of cellular ribonucleoprotein complex localization|regulation of establishment and maintenance of ribonucleoprotein complex localization|regulation of ribonucleoprotein complex localisation|regulation of RNP localization Any process that modulates the frequency, rate or extent of ribonucleoprotein complex localization. CHEBI:85238 15-deoxy-Delta(12,14)-prostaglandin J2-2-glyceryl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85238 CHEBI:61289 (S)-3-sulfonatolactate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61289 GO:2000198 negative regulation of ribonucleoprotein complex localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000198 negative regulation of ribonucleoprotein complex localisation|negative regulation of RNP localization|negative regulation of cellular ribonucleoprotein complex localization|negative regulation of establishment and maintenance of ribonucleoprotein complex localization Any process that stops, prevents, or reduces the frequency, rate or extent of ribonucleoprotein complex localization. GO:2000199 positive regulation of ribonucleoprotein complex localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000199 positive regulation of cellular ribonucleoprotein complex localization|positive regulation of RNP localization|positive regulation of ribonucleoprotein complex localisation|positive regulation of establishment and maintenance of ribonucleoprotein complex localization Any process that activates or increases the frequency, rate or extent of ribonucleoprotein complex localization. GO:2000190 obsolete negative regulation of regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000190 negative regulation of regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor. GO:2000191 regulation of fatty acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000191 Any process that modulates the frequency, rate or extent of fatty acid transport. GO:2000192 negative regulation of fatty acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000192 Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid transport. CHEBI:26959 thiocarboxylic ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26959 GO:2000193 positive regulation of fatty acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000193 Any process that activates or increases the frequency, rate or extent of fatty acid transport. GO:2000194 regulation of female gonad development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000194 regulation of ovary development|regulation of ovarian development Any process that modulates the frequency, rate or extent of female gonad development. CHEBI:26921 tetrahydropyridine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26921 GO:0051930 regulation of sensory perception of pain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051930 Any process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. GO:0051933 amino acid neurotransmitter reuptake biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051933 amino acid uptake during transmission of nerve impulse|amino acid neurotransmitter import into neuron|amino acid neurotransmitter import into glial cell|amino acid neurotransmitter recycling The uptake of amino acid neurotransmitters by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters. GO:0051934 catecholamine uptake involved in synaptic transmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051934 catecholamine neurotransmitter recycling|catecholamine neurotransmitter import into neuron|catecholamine neurotransmitter import into glial cell|catecholamine neurotransmitter reuptake|catecholamine reuptake during transmission of nerve impulse|catecholamine uptake during transmission of nerve impulse The uptake of catecholamine neurotransmitters by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters. CHEBI:61291 (R)-4-phosphopantoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61291 GO:0051931 regulation of sensory perception biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051931 Any process that modulates the frequency, rate or extent of sensory perception, the series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. GO:0051932 synaptic transmission, GABAergic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051932 synaptic transmission, GABA mediated|synaptic transmission, gamma-aminobutyric acid mediated|GABAergic synaptic transmission|synaptic transmission, gamma-aminobutyric acid-ergic The vesicular release of gamma-aminobutyric acid (GABA). from a presynapse, across a chemical synapse, the subsequent activation of GABA receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. CHEBI:26920 tetrahydropteroyltri-L-glutamate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26920 CHEBI:85261 N-dodecanoylsphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85261 GO:0051937 catecholamine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051937 The directed movement of catecholamines, a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. CHEBI:61294 (R)-4-phosphonatopantoate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61294 CHEBI:85262 N-(tetradecanoyl)ethanolamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85262 GO:0051938 L-glutamate import biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051938 L-glutamate uptake The directed movement of L-glutamate, the L-enantiomer of the anion of 2-aminopentanedioic acid, into a cell or organelle. CHEBI:61295 guanyl ribonucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61295 GO:0051935 glutamate reuptake biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051935 glutamate uptake during transmission of nerve impulse|L-glutamate reuptake|L-glutamate uptake during transmission of nerve impulse|L-glutamate uptake involved in synaptic transmission|glutamate recycling|glutamate import into glial cell|glutamate import into neuron The uptake of L-glutamate by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters. CHEBI:85263 N-(dodecanoyl)ethanolamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85263 CHEBI:61292 guanyl nucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61292 CHEBI:61293 adenyl nucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61293 GO:0051936 gamma-aminobutyric acid reuptake biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051936 gamma-aminobutyric acid uptake during transmission of nerve impulse|gamma-aminobutyric acid uptake involved in synaptic transmission|gamma-aminobutyric acid recycling|GABA import into neuron|GABA import into glial cell|GABA recycling|gamma-aminobutyric acid import into neuron|GABA reuptake|gamma-aminobutyric acid import into glial cell The uptake of gamma-aminobutyric acid (GABA, 4-aminobutyrate) by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters. CHEBI:61298 D-glucose- and/or D-galactose-substituted mannan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61298 GO:0051939 gamma-aminobutyric acid import biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051939 gamma-aminobutyrate import|gamma-aminobutyric acid uptake|GABA import|4-aminobutyrate import The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a cell or organelle. CHEBI:61296 adenyl ribonucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61296 CHEBI:85268 (5Z)-icosenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85268 CHEBI:61297 adenyl deoxyribonucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61297 CHEBI:26925 naphthalenetetrol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26925 GO:0051940 regulation of catecholamine uptake involved in synaptic transmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051940 regulation of catecholamine uptake during transmission of nerve impulse|regulation of catecholamine neurotransmitter uptake|regulation of catecholamine neurotransmitter reuptake Any process that modulates the frequency, rate or extent of the directed movement of catecholamine neurotransmitters into a neuron or glial cell. CHEBI:26932 tetrapyrrole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26932 CHEBI:26933 tetraric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26933 GO:0051941 regulation of amino acid uptake involved in synaptic transmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051941 regulation of amino acid neurotransmitter uptake|regulation of amino acid neurotransmitter reuptake|regulation of amino acid uptake during transmission of nerve impulse Any process that modulates the frequency, rate or extent of the directed movement of amino acid neurotransmitters into a neuron or glial cell. CHEBI:26935 tetraterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26935 GO:0051944 positive regulation of catecholamine uptake involved in synaptic transmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051944 positive regulation of catecholamine neurotransmitter reuptake|upregulation of catecholamine uptake during transmission of nerve impulse|up regulation of catecholamine uptake during transmission of nerve impulse|activation of catecholamine uptake during transmission of nerve impulse|positive regulation of catecholamine uptake during transmission of nerve impulse|stimulation of catecholamine uptake during transmission of nerve impulse|positive regulation of catecholamine neurotransmitter uptake|up-regulation of catecholamine uptake during transmission of nerve impulse Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of catecholamine neurotransmitters into a neuron or glial cell. GO:0051945 negative regulation of catecholamine uptake involved in synaptic transmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051945 negative regulation of catecholamine neurotransmitter reuptake|down regulation of catecholamine uptake during transmission of nerve impulse|downregulation of catecholamine uptake during transmission of nerve impulse|negative regulation of catecholamine uptake during transmission of nerve impulse|down-regulation of catecholamine uptake during transmission of nerve impulse|negative regulation of catecholamine neurotransmitter uptake|inhibition of catecholamine uptake during transmission of nerve impulse Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of catecholamine neurotransmitters into a neuron or glial cell. GO:0051942 negative regulation of amino acid uptake involved in synaptic transmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051942 downregulation of amino acid uptake during transmission of nerve impulse|negative regulation of amino acid neurotransmitter reuptake|down regulation of amino acid uptake during transmission of nerve impulse|inhibition of amino acid uptake during transmission of nerve impulse|negative regulation of amino acid uptake during transmission of nerve impulse|negative regulation of amino acid neurotransmitter uptake|down-regulation of amino acid uptake during transmission of nerve impulse Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acid neurotransmitters into a neuron or glial cell. GO:0051943 positive regulation of amino acid uptake involved in synaptic transmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051943 positive regulation of amino acid neurotransmitter uptake|up regulation of amino acid uptake during transmission of nerve impulse|upregulation of amino acid uptake during transmission of nerve impulse|positive regulation of amino acid neurotransmitter reuptake|stimulation of amino acid uptake during transmission of nerve impulse|up-regulation of amino acid uptake during transmission of nerve impulse|activation of amino acid uptake during transmission of nerve impulse Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acid neurotransmitters into a neuron or glial cell. GO:0051948 negative regulation of glutamate uptake involved in transmission of nerve impulse biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051948 down regulation of glutamate uptake during transmission of nerve impulse|negative regulation of glutamate uptake involved in conduction of nerve impulse|downregulation of glutamate uptake during transmission of nerve impulse|negative regulation of glutamate uptake during transmission of nerve impulse|down-regulation of glutamate uptake during transmission of nerve impulse|negative regulation of glutamate reuptake|inhibition of glutamate uptake during transmission of nerve impulse Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell. CHEBI:85250 N-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycero-3-phosphoethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85250 GO:0051949 negative regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051949 negative regulation of GABA uptake during transmission of nerve impulse|negative regulation of gamma-aminobutyric acid uptake involved in conduction of nerve impulse|down regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|negative regulation of GABA reuptake|downregulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|negative regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|negative regulation of 4-aminobutyrate reuptake|down-regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|negative regulation of gamma-aminobutyric acid reuptake|negative regulation of 4-aminobutyrate uptake during transmission of nerve impulse|inhibition of gamma-aminobutyric acid uptake during transmission of nerve impulse Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell. GO:0051946 regulation of glutamate uptake involved in transmission of nerve impulse biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051946 regulation of glutamate uptake during transmission of nerve impulse|regulation of L-glutamate reuptake|regulation of glutamate reuptake|regulation of L-glutamate uptake during transmission of nerve impulse|regulation of glutamate uptake involved in conduction of nerve impulse Any process that modulates the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell. CHEBI:85252 N-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoylethanolamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85252 GO:0051947 regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051947 regulation of GABA reuptake|regulation of gamma-aminobutyric acid reuptake|regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|regulation of GABA uptake during transmission of nerve impulse|regulation of 4-aminobutyrate uptake during transmission of nerve impulse|regulation of gamma-aminobutyric acid uptake involved in conduction of nerve impulse|regulation of 4-aminobutyrate reuptake Any process that modulates the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell. CHEBI:85253 N-(icosanoyl)ethanolamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85253 CHEBI:26936 tetrathionate ion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26936 CHEBI:26937 monoatomic tetracation biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_26937 CHEBI:26938 tetrose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26938 GO:0051951 positive regulation of glutamate uptake involved in transmission of nerve impulse biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051951 up-regulation of glutamate uptake during transmission of nerve impulse|positive regulation of glutamate reuptake|upregulation of glutamate uptake during transmission of nerve impulse|positive regulation of glutamate uptake during transmission of nerve impulse|positive regulation of glutamate uptake involved in conduction of nerve impulse|up regulation of glutamate uptake during transmission of nerve impulse|activation of glutamate uptake during transmission of nerve impulse|stimulation of glutamate uptake during transmission of nerve impulse Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell. CL:0013000 forebrain radial glial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0013000 GO:0051952 regulation of amine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051952 Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:26900 tetradecenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26900 CHEBI:26901 benzyltetrahydroisoquinoline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26901 GO:0051950 positive regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051950 positive regulation of 4-aminobutyrate uptake during transmission of nerve impulse|positive regulation of 4-aminobutyrate reuptake|positive regulation of gamma-aminobutyric acid reuptake|up-regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|upregulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|positive regulation of GABA uptake during transmission of nerve impulse|positive regulation of GABA reuptake|positive regulation of gamma-aminobutyric acid uptake involved in conduction of nerve impulse|positive regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|up regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|activation of gamma-aminobutyric acid uptake during transmission of nerve impulse|stimulation of gamma-aminobutyric acid uptake during transmission of nerve impulse Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell. GO:0051955 regulation of amino acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051955 Any process that modulates the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0051956 negative regulation of amino acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051956 down-regulation of amino acid transport|negative regulation of amino acid transmembrane transport|downregulation of amino acid transport|down regulation of amino acid transport|inhibition of amino acid transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:85280 S-3-[(2R)-phycocyanobilin]-L-cysteine(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85280 CHEBI:85281 N-(polyunsaturated fatty acyl)ethanolamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85281 GO:0051953 negative regulation of amine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051953 down regulation of amine transport|downregulation of amine transport|down-regulation of amine transport|inhibition of amine transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:85282 N-(monounsaturated fatty acyl)ethanolamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85282 GO:0051954 positive regulation of amine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051954 upregulation of amine transport|up regulation of amine transport|activation of amine transport|stimulation of amine transport|up-regulation of amine transport Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0051959 dynein light intermediate chain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051959 Interacting selectively and non-covalently with a light intermediate chain of the dynein complex. CHEBI:85283 N-(saturated fatty acyl)ethanolamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85283 GO:2000148 regulation of planar cell polarity pathway involved in ventricular septum morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000148 Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in ventricular septum morphogenesis. CHEBI:85284 N-(11Z)-icosenoylsphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85284 GO:2000149 negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000149 Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in ventricular septum morphogenesis. GO:0051957 positive regulation of amino acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051957 upregulation of amino acid transport|stimulation of amino acid transport|up-regulation of amino acid transport|activation of amino acid transport|up regulation of amino acid transport|positive regulation of amino acid transmembrane transport Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:85285 N-(11Z)-icosenoylsphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85285 CHEBI:85286 N-(11Z)-icosenoylphytosphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85286 GO:0051958 methotrexate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051958 The directed movement of methotrexate, 4-amino-10-methylformic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Methotrexate is a folic acid analogue and a potent competitive inhibitor of dihydrofolate reductase. CHEBI:85288 S-3-[(2R)-phycoviolobilin]-L-cysteine(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85288 GO:2000140 negative regulation of octopamine signaling pathway involved in response to food biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000140 negative regulation of octopamine signalling pathway involved in response to food Any process that stops, prevents, or reduces the frequency, rate or extent of octopamine signaling pathway involved in response to food. GO:0036398 TCR signalosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036398 LAT signalosome|linker for activation of T cells signalosome A multi-protein complex containing at least the T-cell receptor complex and the LAT (linker for activation of T cells) scaffold protein. Also contains a variety of signaling proteins including co-receptors, kinases, phosphatases and adaptors such as CD8. Connects events on the plasma membrane to distal signaling cascades to ultimately modulate T cell biology. GO:0036399 TCR signalosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036399 linker for activation of T cells signalosome assembly|LAT signalosome assembly The aggregation, arrangement and bonding together of a set of components to form a TCR signalosome. GO:2000141 positive regulation of octopamine signaling pathway involved in response to food biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000141 positive regulation of octopamine signalling pathway involved in response to food Any process that activates or increases the frequency, rate or extent of octopamine signaling pathway involved in response to food. GO:2000142 regulation of DNA-templated transcription, initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000142 regulation of DNA-dependent transcription, initiation|regulation of initiation of DNA-dependent transcription|regulation of transcription initiation, DNA-dependent Any process that modulates the frequency, rate or extent of DNA-templated transcription initiation. GO:2000143 negative regulation of DNA-templated transcription, initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000143 negative regulation of DNA-dependent transcription, initiation|negative regulation of initiation of DNA-dependent transcription|negative regulation of transcription initiation, DNA-dependent Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-templated transcription initiation. GO:2000144 positive regulation of DNA-templated transcription, initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000144 positive regulation of DNA-dependent transcription, initiation|transcriptional transactivation|positive regulation of initiation of DNA-dependent transcription|positive regulation of transcription initiation, DNA-dependent|transactivation Any process that activates or increases the frequency, rate or extent of DNA-templated transcription initiation. GO:2000145 regulation of cell motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000145 regulation of cell movement|regulation of cell locomotion|regulation of movement of a cell Any process that modulates the frequency, rate or extent of cell motility. GO:2000146 negative regulation of cell motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000146 negative regulation of cell locomotion|negative regulation of movement of a cell|negative regulation of cell movement Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility. GO:2000147 positive regulation of cell motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000147 positive regulation of movement of a cell|positive regulation of cell movement|positive regulation of cell locomotion Any process that activates or increases the frequency, rate or extent of cell motility. GO:0036390 pre-replicative complex assembly involved in bacterial-type DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036390 bacterial pre-RC assembly|bacterial pre-replicative complex assembly The aggregation, arrangement and bonding together of a set of components to form the bacterial pre-replicative complex, a protein-DNA complex that forms at the bacterial oriC during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication. CHEBI:26907 tetrahydrofolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26907 GO:0036391 medial cortex septin ring biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036391 A ring-shaped structure that forms at the medial cortex of a symmetrically dividing cell at the onset of cytokinesis; composed of members of the conserved family of filament forming proteins called septins as well as septin-associated proteins. CHEBI:26908 tetrahydrofolyl glutamate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26908 GO:0036392 chemokine (C-C motif) ligand 20 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0036392 CCL-20 production|C-C motif chemokine 20 production|CCL20 production The appearance of chemokine (C-C motif) ligand 20 (CCL20) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0036393 thiocyanate peroxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036393 lactoperoxidase activity Catalysis of the reaction: thiocyanate (SCN-) + hydrogen peroxide (H2O2) = hypothiocyanite (OSCN-) + 2 H2O. Catalyzes the hydrogen peroxide oxidation of thiocyanate. GO:0036394 amylase secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036394 amylase release The controlled release of amylase from a cell. GO:0036395 pancreatic amylase secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036395 The controlled release of amylase from a cell of the pancreas. CHEBI:26904 tetrahydrocorphin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26904 GO:0036396 RNA N6-methyladenosine methyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036396 m6A methyltransferase complex|m(6)A writer complex|WMM complex|METTL3-METTL14-WTAP methyltransferase complex|MIS complex|Mum2, Ime4, and Slz1 complex A RNA methyltransferase complex that catalyzes the post-transcriptional methylation of adenosine to form N6-methyladenosine (m6A). In budding yeast, the MIS complex consists of Mum2p, Ime4p and Slz1p. In vertebrates, the complex consists of METTL3, METTL14 and associated components WTAP, ZC3H13, VIRMA, CBLL1/HAKAI and in some cases of RBM15 (RBM15 or RBM15B). GO:0036397 formate dehydrogenase (quinone) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036397 EC:1.1.5.6|KEGG_REACTION:R09494|MetaCyc:FORMATEDEHYDROG-RXN Fdh-N activity|formate dehydrogenase-N activity|formate:quinone oxidoreductase activity Catalysis of the reaction: formate + a quinone = CO2 + a quinol. GO:0051962 positive regulation of nervous system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051962 stimulation of nervous system development|up-regulation of nervous system development|activation of nervous system development|up regulation of nervous system development|upregulation of nervous system development Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue. CHEBI:26911 oxolane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_26911 GO:0051963 regulation of synapse assembly biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0051963 regulation of synapse biogenesis|regulation of synaptogenesis Any process that modulates the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse. CHEBI:26912 oxolanes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26912 GO:0051960 regulation of nervous system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051960 Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue. GO:0051961 negative regulation of nervous system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051961 down-regulation of nervous system development|downregulation of nervous system development|down regulation of nervous system development|inhibition of nervous system development Any process that stops, prevents, or reduces the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue. GO:0051966 regulation of synaptic transmission, glutamatergic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051966 Any process that modulates the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate. GO:0051967 negative regulation of synaptic transmission, glutamatergic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051967 downregulation of synaptic transmission, glutamatergic|down regulation of synaptic transmission, glutamatergic|inhibition of synaptic transmission, glutamatergic|down-regulation of synaptic transmission, glutamatergic Any process that stops, prevents, or reduces the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate. CHEBI:85270 1,2-dihexadecanoyl-sn-glycero-3-phosphoglycerol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85270 GO:0051964 negative regulation of synapse assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051964 down-regulation of synapse assembly|negative regulation of synapse biogenesis|negative regulation of synaptogenesis|downregulation of synapse assembly|down regulation of synapse assembly|inhibition of synapse assembly Any process that stops, prevents, or reduces the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse. GO:0051965 positive regulation of synapse assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051965 stimulation of synapse assembly|up-regulation of synapse assembly|activation of synapse assembly|up regulation of synapse assembly|positive regulation of synapse biogenesis|positive regulation of synaptogenesis|upregulation of synapse assembly Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse. CHEBI:85271 (Kdo)2-lipid A 1-diphosphate(7-) (E. coli) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85271 GO:2000159 regulation of planar cell polarity pathway involved in heart morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000159 Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in heart morphogenesis. GO:0051968 positive regulation of synaptic transmission, glutamatergic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051968 upregulation of synaptic transmission, glutamatergic|stimulation of synaptic transmission, glutamatergic|activation of synaptic transmission, glutamatergic|up-regulation of synaptic transmission, glutamatergic|up regulation of synaptic transmission, glutamatergic Any process that activates, maintains or increases the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate. GO:0051969 regulation of transmission of nerve impulse biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051969 regulation of conduction of nerve impulse Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation. CHEBI:85275 (3E)-phycocyanobilin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85275 CHEBI:85276 (3E)-phycoerythrobilin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85276 CHEBI:85277 N-arachidonoyl-1,2-dioleoyl-sn-glycero-3-phosphoethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85277 CHEBI:85278 17beta-hydroxyandrostan-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85278 CHEBI:85279 S-3-[(2R)-phycoerythrobilin]-L-cysteine(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85279 GO:0036387 pre-replicative complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036387 pre-RC|pre-replication complex A protein-DNA complex that forms at the origin of replication during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication. GO:2000151 negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000151 Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis. GO:0036388 pre-replicative complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036388 pre-replication complex assembly|pre-RC assembly The aggregation, arrangement and bonding together of a set of components to form the pre-replicative complex, a protein-DNA complex that forms at the origin of replication during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication. GO:2000152 regulation of ubiquitin-specific protease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000152 regulation of UBP|regulation of UCH2|regulation of deubiquitinase activity Any process that modulates the frequency, rate or extent of regulation of ubiquitin-specific protease activity (deubiquitinase) activity. GO:0120300 peptide lactyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120300 RHEA:61997 Catalysis of the reaction: (L-lysyl-[protein] + lactoyl-CoA = CoA + H(+) + N(6)-lactoyl-L-lysyl-[protein]. GO:0036389 bacterial pre-replicative complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036389 bacterial pre-RC A protein-DNA complex that forms at the bacterial oriC during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication. GO:0120301 histone lactyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120301 Catalysis of the reaction: (L-lysyl-[histone] + lactoyl-CoA = CoA + H(+) + N(6)-lactoyl-L-lysyl-[histone]. GO:2000153 obsolete regulation of flagellar cell motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000153 regulation of flagellar cell motility OBSOLETE. Any process that modulates the frequency, rate or extent of flagellar cell motility. GO:2000154 obsolete negative regulation of flagellar cell motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000154 negative regulation of flagellar cell motility OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of flagellar cell motility. GO:2000155 positive regulation of cilium-dependent cell motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000155 positive regulation of ciliary cell motility Any process that activates or increases the frequency, rate or extent of cilium-dependent cell motility. GO:2000156 regulation of retrograde vesicle-mediated transport, Golgi to ER biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000156 regulation of retrograde transport, Golgi to ER|regulation of retrograde (Golgi to ER) transport|regulation of retrograde transport, Golgi to endoplasmic reticulum|regulation of cis-Golgi to rough ER vesicle-mediated transport|regulation of cis-Golgi to rough endoplasmic reticulum vesicle-mediated transport|regulation of cis-Golgi to rough endoplasmic reticulum transport|regulation of cis-Golgi to rough ER transport|regulation of retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum Any process that modulates the frequency, rate or extent of retrograde vesicle-mediated transport, Golgi to ER. GO:2000157 negative regulation of ubiquitin-specific protease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000157 negative regulation of UCH2|negative regulation of deubiquitinase activity|negative regulation of ubiquitin hydrolase activity|negative regulation of UBP Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin-specific protease (deubiquitinase) activity. GO:2000158 positive regulation of ubiquitin-specific protease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000158 positive regulation of deubiquitinase activity|positive regulation of UCH2|positive regulation of UBP|positive regulation of ubiquitin hydrolase activity Any process that activates or increases the frequency, rate or extent of ubiquitin-specific protease (deubiquitinase) activity. GO:0036380 UDP-N-acetylglucosamine-undecaprenyl-phosphate N-acetylglucosaminephosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036380 RHEA:28090|MetaCyc:GLCNACPTRANS-RXN|KEGG_REACTION:R08856|EC:2.7.8.33 UDP-N-acetylglucosamine:undecaprenyl-phosphate GlcNAc-1-phosphate transferase activity|GlcNAc-P-P-Und synthase activity|UDP-GIcNAc:undecaprenyl phosphate N-acetylglucosaminyl 1-P transferase activity|UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase activity|UDP-N-acetyl-D-glucosamine:ditrans,octacis-undecaprenyl phosphate N-acetyl-D-glucosaminephosphotransferase activity Catalysis of the reaction: UDP-N-acetyl-alpha-D-glucosamine + ditrans,octacis-undecaprenyl phosphate = UMP + N-acetyl-alpha-D-glucosaminyldiphospho-ditrans,octacis-undecaprenol. GO:0036381 pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036381 MetaCyc:RXN-11322|RHEA:31507|KEGG_REACTION:R10089|EC:4.3.3.6 PdxST activity|pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) activity Catalysis of the reaction: D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = pyridoxal 5'-phosphate + L-glutamate + 3 H2O + phosphate. The reaction occurs in two steps: L-glutamine + H2O = L-glutamate + NH3, and subsequently D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + NH3 = pyridoxal 5'-phosphate + 4 H2O + phosphate. GO:0036382 flavin reductase (NADH) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036382 EC:1.5.1.36|RHEA:31303|MetaCyc:1.5.1.36-RXN|KEGG_REACTION:R09662 NADH-dependent flavin reductase activity|flavin:NADH oxidoreductase activity Catalysis of the reaction: reduced flavin + NAD+ = flavin + NADH + H+. CHEBI:26914 tetrahydromethanopterin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26914 GO:0036383 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036383 EC:1.14.14.12|KEGG_REACTION:R09819|RHEA:31731|MetaCyc:1.14.14.12-RXN Catalysis of the reaction: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMNH2 + O2 = 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMN + H2O. GO:0036384 cytidine-diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036384 CDPase activity Catalysis of the reaction: CDP + H2O = CMP + phosphate. GO:0036385 nucleoid DNA packaging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036385 Any process in which DNA and associated proteins are formed into a compact, orderly structure within a nucleoid. CHEBI:26916 tetrahydronicotinamide adenine dinucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26916 GO:2000150 regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000150 Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis. GO:0036386 bacterial nucleoid DNA packaging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036386 prokaryotic DNA condensation|nucleoid compaction|chromosomal compaction Compaction of DNA in a bacterial nucleoid into a compact structure. Often achieved by DNA supercoiling. GO:0051973 positive regulation of telomerase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051973 up regulation of telomerase activity|activation of telomerase activity|stimulation of telomerase activity|telomerase activator|up-regulation of telomerase activity|upregulation of telomerase activity Any process that activates or increases the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). GO:0051974 negative regulation of telomerase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051974 telomerase inhibitor|down regulation of telomerase activity|downregulation of telomerase activity|down-regulation of telomerase activity|inhibition of telomerase activity Any process that stops or reduces the activity of the enzyme telomerase, which catalyzes of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). GO:0051971 positive regulation of transmission of nerve impulse biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051971 up-regulation of transmission of nerve impulse|positive regulation of conduction of nerve impulse|upregulation of transmission of nerve impulse|up regulation of transmission of nerve impulse|activation of transmission of nerve impulse|stimulation of transmission of nerve impulse Any process that activates, maintains or increases the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation. GO:0051972 regulation of telomerase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051972 telomerase regulator Any process that modulates the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Telomerases catalyze extension of the 3'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence. GO:0051977 lysophospholipid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051977 The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A lysophospholipid is a phospholipid that lacks one of its fatty acyl chains; it is an intermediate formed during digestion of dietary and biliary phospholipids. GO:0051978 lysophospholipid:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051978 lysophospholipid transporter activity Enables the directed movement of lysophospholipids from one side of a membrane to the other. A lysophospholipid is a phospholipid that lacks one of its fatty acyl chains; it is an intermediate formed during digestion of dietary and biliary phospholipids. GO:0051975 lysine biosynthetic process via alpha-aminoadipate and saccharopine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051975 MetaCyc:LYSINE-AMINOAD-PWY lysine biosynthetic process via aminoadipic acid and saccharopine|lysine biosynthesis via aminoadipic acid and saccharopine The chemical reactions and pathways resulting in the formation of lysine via the intermediates alpha-aminoadipic acid and saccharopine. This pathway is used by yeast and fungi to synthesize the essential amino acid L-lysine, and pathway intermediates are often incorporated into secondary metabolic processes. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This is then reduced to form alpha-aminoadipate 6-semialdehyde, which is metabolized to saccharopine and finally L-lysine. GO:0051976 lysine biosynthetic process via alpha-aminoadipate and N2-acetyl-alpha-aminoadipate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051976 MetaCyc:PWY-3081 lysine biosynthesis via aminoadipic acid and N2-acetyl-alpha-aminoadipate|lysine biosynthetic process via aminoadipic acid and N2-acetyl-alpha-aminoadipate The chemical reactions and pathways resulting in the formation of lysine via the intermediates alpha-aminoadipic acid and N2-acetyl-alpha-aminoadipate. This pathway of prokaryotic lysine biosynthesis via alpha-aminoadipate was discovered in the hyper-thermophilic Gram-negative eubacterium Thermus thermophilus. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This undergoes acetylation, to form N2-acetyl-alpha-aminoadipate, and is then phosphorylated to give N2-acetyl-alpha-aminoadipyl-delta-phosphate. This is converted to N2-acetyl-alpha-aminoadipate semialdehyde, which is then converted to N2-acetyl-L-lysine. A final deacetylation reaction produces L-lysine. GO:0051979 alginic acid acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051979 alginate acetylation The addition of O-acetyl ester groups to alginic acid, a linear polymer of D-mannuronate and L-guluronate. GO:0036376 sodium ion export across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036376 sodium export|sodium ion export|sodium ion export from cell The directed movement of sodium ions from inside of a cell, across the plasma membrane and into the extracellular region. GO:2000162 negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000162 Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in cardiac right atrium morphogenesis. GO:0036377 arbuscular mycorrhizal association biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036377 arbuscular mycorrhizas formation|arbuscular mycorrhizal symbiosis|arbuscular mycorrhizae formation A form of mutualism between a fungus and the roots of a vascular plant, where hyphae of the fungus penetrate the plant cell wall and invaginate its cell membrane. Once inside, the fungus forms highly branched structures for nutrient exchange with the plant called arbuscules. Aids in the acquisition by the plant of nutrients such as phosphorus from the soil. GO:0061300 cerebellum vasculature development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061300 The process whose specific outcome is the progression of the vasculature of the cerebellum over time, from its formation to the mature structure. GO:2000163 regulation of planar cell polarity pathway involved in outflow tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000163 Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in outflow tract morphogenesis. GO:0061301 cerebellum vasculature morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061301 The process in which the vasculature of the cerebellum is generated and organized. GO:0036378 calcitriol biosynthetic process from calciol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036378 calcitriol biosynthesis from calciol|vitamin D3 activation|1alpha,25(OH)2D3 biosynthesis|1alpha,25-dihydroxyvitamin D3 biosynthesis|1alpha,25-dihydroxycholecalciferol biosynthesis Conversion of vitamin D3 from its largely inactive form (calciol, also called cholecalciferol) into a hormonally active form (calcitriol). Conversion requires 25-hydroxylation of calciol in the liver to form calcidiol, and subsequent 1,alpha-hydroxylation of calcidiol in the kidney to form calcitriol. GO:2000164 negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000164 Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in outflow tract morphogenesis. GO:0061302 smooth muscle cell-matrix adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061302 The binding of a smooth muscle cell to the extracellular matrix via adhesion molecules. GO:2000165 regulation of planar cell polarity pathway involved in pericardium morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000165 Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in pericardium morphogenesis. GO:0036379 myofilament biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036379 striated muscle filament Any of the smallest contractile units of a myofibril (striated muscle fiber). GO:0061303 cornea development in camera-type eye biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061303 The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye. GO:2000166 negative regulation of planar cell polarity pathway involved in pericardium morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000166 Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in pericardium morphogenesis. GO:2000167 regulation of planar cell polarity pathway involved in neural tube closure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000167 Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in neural tube closure. GO:0061304 retinal blood vessel morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061304 The process whose specific outcome is the progression of a blood vessel of the retina over time, from its formation to the mature structure. GO:0061305 maintenance of bipolar cell polarity regulating cell shape biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061305 The maintenance of established bipolar anisotropic intracellular organization or cell growth patterns that results in the shaping of a cell. GO:2000168 negative regulation of planar cell polarity pathway involved in neural tube closure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000168 Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in neural tube closure. GO:0061306 DNA strand renaturation involved in double-strand break repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061306 The identification and annealing of complementary base pairs in single-strand DNA that contributes to double-strand break repair. GO:2000169 regulation of peptidyl-cysteine S-nitrosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000169 Any process that modulates the frequency, rate or extent of peptidyl-cysteine S-nitrosylation. GO:0061307 cardiac neural crest cell differentiation involved in heart development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061307 The process in which a relatively unspecialized cell acquires specialized features of a cardiac neural crest cell that will migrate to the heart and contribute to its development. Cardiac neural crest cells are specialized cells that migrate toward the heart from the third, fourth and sixth pharyngeal arches. GO:0061308 cardiac neural crest cell development involved in heart development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061308 The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the development of the heart. GO:0061309 cardiac neural crest cell development involved in outflow tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061309 The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the shaping of the outflow tract. GO:0036370 D-alanyl carrier activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036370 D-alanyl carrier protein Binding a D-alanine and presenting it for processing or offloading to a cognate enzyme. Covalently binds the D-alanine via a phosphopantetheine prosthetic group and mediates protein-protein interactions with the enzyme conferring specificity. The carrier protein provides an essential link between the D-alanine-D-alanyl carrier protein ligase and the incorporation of D-alanine into lipoteichoic acid by transferring activated D-alanine to cell membrane phosphatidylglycerol (PG). GO:0036371 protein localization to T-tubule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036371 protein localization to T tubule|protein localisation to T-tubule|protein localization to transverse tubule A process in which a protein is transported to, or maintained in, the T-tubule. The T-tubule is an invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. GO:0036372 opsin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036372 ciliary transport of opsin The directed movement of an opsin (a G protein-coupled receptor of photoreceptor cells) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. GO:0051970 negative regulation of transmission of nerve impulse biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051970 inhibition of transmission of nerve impulse|negative regulation of conduction of nerve impulse|down regulation of transmission of nerve impulse|downregulation of transmission of nerve impulse|down-regulation of transmission of nerve impulse Any process that stops, prevents, or reduces the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation. GO:0036373 L-fucose mutarotase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036373 MetaCyc:RXN0-5298|RHEA:25580|EC:5.1.3.29 alpha-L-fucose 1-epimerase activity|fucose 1-epimerase activity|type-2 mutarotase activity Catalysis of the reaction: alpha-L-fucose = beta-L-fucose. GO:0036374 glutathione hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036374 Reactome:R-HSA-5433072|KEGG_REACTION:R00494|Reactome:R-HSA-9035966|Reactome:R-HSA-8943279|MetaCyc:RXN-12618|Reactome:R-HSA-266046|Reactome:R-HSA-9026907|Reactome:R-HSA-9026927|Reactome:R-HSA-9026916|Reactome:R-HSA-5602984|Reactome:R-HSA-9026912|Reactome:R-HSA-9026757|EC:3.4.19.13|RHEA:28807|Reactome:R-HSA-1222712 glutathionase activity|gamma-glutamyltranspeptidase activity Catalysis of the reaction: glutathione + H2O = L-cysteinylglycine + L-glutamate. GO:2000160 negative regulation of planar cell polarity pathway involved in heart morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000160 Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in heart morphogenesis. GO:0036375 Kibra-Ex-Mer complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036375 KEM complex|Kbr, Ex and Mer complex An apical protein complex that contains the proteins Kibra, Expanded and Merlin (Mer), or orthologs thereof. In humans, the complex contains KIBRA, FDM6 and NF2. GO:2000161 regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000161 Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in cardiac right atrium morphogenesis. GO:0051984 positive regulation of chromosome segregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051984 upregulation of chromosome segregation|stimulation of chromosome segregation|up-regulation of chromosome segregation|activation of chromosome segregation|up regulation of chromosome segregation Any process that activates or increases the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets. GO:0051985 negative regulation of chromosome segregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051985 down regulation of chromosome segregation|inhibition of chromosome segregation|down-regulation of chromosome segregation|downregulation of chromosome segregation Any process that stops, prevents, or reduces the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets. GO:0051982 copper-nicotianamine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051982 Cu-NA chelate transporter activity Enables the transfer of the copper chelate copper-nicotianamine (Cu-NA) from one side of a membrane to the other. GO:0051983 regulation of chromosome segregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051983 Any process that modulates the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets. GO:0051988 regulation of attachment of spindle microtubules to kinetochore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051988 regulation of kinetochore-microtubule attachment Any process that modulates the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore. GO:0051989 coproporphyrinogen dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051989 EC:1.3.98.3|RHEA:15425|MetaCyc:HEMN-RXN radical SAM enzyme activity|coproporphyrinogen-III:S-adenosyl-L-methionine oxidoreductase (decarboxylating)|HemN|oxygen-independent coproporphyrinogen-III oxidase activity|coproporphyrinogen III oxidase activity Catalysis of the reaction: coproporphyrinogen III + 2 S-adenosyl-L-methionine = protoporphyrinogen IX + 2 CO2 + 2 L-methionine + 2 5'-deoxyadenosine. CHEBI:85291 N,1,2-trioleoyl-sn-glycero-3-phosphoethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85291 GO:0051986 negative regulation of attachment of spindle microtubules to kinetochore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051986 downregulation of attachment of spindle microtubules to kinetochore|down-regulation of attachment of spindle microtubules to kinetochore|inhibition of attachment of spindle microtubules to kinetochore|down regulation of attachment of spindle microtubules to kinetochore Any process that stops, prevents, or reduces the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore. CHEBI:85292 N-stearoyl-1,2-dioleoyl-sn-glycero-3-phosphoethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85292 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051987 up regulation of attachment of spindle microtubules to kinetochore|activation of attachment of spindle microtubules to kinetochore|stimulation of attachment of spindle microtubules to kinetochore|up-regulation of attachment of spindle microtubules to kinetochore|upregulation of attachment of spindle microtubules to kinetochore Any process that activates or increases the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore. CHEBI:85293 N-myristoyl-1,2-dioleoyl-sn-glycero-3-phosphoethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85293 CHEBI:85294 N-lauroyl-1,2-dioleoyl-sn-glycero-3-phosphoethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85294 CHEBI:85295 N-capryl-1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85295 CHEBI:85296 N-capryloyl-1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85296 CHEBI:85297 N-caproyl-1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85297 CHEBI:85298 N-butyryl-1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85298 CHEBI:85299 N-(octadecanoyl)ethanolamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85299 GO:2000173 negative regulation of branching morphogenesis of a nerve biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000173 Any process that stops, prevents, or reduces the frequency, rate or extent of branching morphogenesis of a nerve. GO:0036365 transforming growth factor beta2 activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036365 TGF-beta 2 activation|TGFB2 activation|TGFbeta 2 activation The release of transforming growth factor beta 2 (TGF-beta2) from its latent state. GO:2000174 regulation of pro-T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000174 regulation of pro-T lymphocyte differentiation Any process that modulates the frequency, rate or extent of pro-T cell differentiation. GO:0036366 transforming growth factor beta3 activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036366 TGF-beta 3 activation|TGFB3 activation|TGFbeta 3 activation The release of transforming growth factor beta 3 (TGF-beta3) from its latent state. GO:2000175 negative regulation of pro-T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000175 negative regulation of pro-T lymphocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of pro-T cell differentiation. GO:0036367 light adaption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036367 The ability of a photoreceptor to adjust to varying levels of light. GO:2000176 positive regulation of pro-T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000176 positive regulation of pro-T lymphocyte differentiation Any process that activates or increases the frequency, rate or extent of pro-T cell differentiation. GO:0036368 cone photoresponse recovery biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036368 cone phototransduction termination|cone response recovery The processes required for a cone photoreceptor to recover, following light activation, so that it can respond to a subsequent light stimulus. Cone recovery requires the shutoff of active participants in the phototransduction cascade, including the visual pigment and downstream signal transducers. GO:0036369 transcription factor catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036369 proteasome-mediated transcription factor catabolism|transcription factor catabolism|transcription factor degradation|sequence-specific DNA binding transcription factor catabolic process|transcription factor breakdown The chemical reactions and pathways resulting in the breakdown of a sequence-specific DNA-binding transcription factor by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome. GO:2000177 regulation of neural precursor cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000177 Any process that modulates the frequency, rate or extent of neural precursor cell proliferation. GO:2000178 negative regulation of neural precursor cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000178 Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation. GO:2000179 positive regulation of neural precursor cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000179 Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation. GO:0036360 sorocarp stalk morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036360 fruiting body stalk morphogenesis The process in which the sorocarp stalk is generated and organized. The sorocarp stalk is a tubular structure that consists of cellulose-covered cells stacked on top of each other and surrounded by an acellular stalk tube composed of cellulose and glycoprotein. An example of this process is found in Dictyostelium discoideum. GO:0036361 racemase activity, acting on amino acids and derivatives biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036361 Catalysis of the interconversion of the two enantiomers of a chiral amino acid or amino acid derivative. GO:0051980 iron-nicotianamine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051980 Fe-NA chelate transporter activity Enables the transfer of the iron chelate iron-nicotianamine (Fe-NA) from one side of a membrane to the other. GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000170 Any process that activates or increases the frequency, rate or extent of peptidyl-cysteine S-nitrosylation. GO:0036362 ascus membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036362 A double layer of lipid molecules that surrounds an ascus, a capsule containing the sexual spores in some fungi. GO:0051981 copper chelate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051981 Enables the transfer of a copper chelate from one side of a membrane to the other. A copper chelate is a heterocyclic compound having a metal ion attached by coordinate bonds to at least two nonmetal ions. GO:0036363 transforming growth factor beta activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036363 L-TGF-beta activation|TGFbeta activation|TGFB activation|latent TGF-beta activation|TGF-B activation|TGF-beta activation The release of transforming growth factor beta (TGF-beta) from its latent state. TGF-beta is secreted as part of a large latent complex (LLC) that is targeted to the extracellular matrix. Release of TGFbeta from its latent state is required for TGFbeta to bind to its receptors, and can occur by a variety of mechanisms. GO:2000171 negative regulation of dendrite development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000171 Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite development. GO:2000172 regulation of branching morphogenesis of a nerve biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000172 Any process that modulates the frequency, rate or extent of branching morphogenesis of a nerve. GO:0036364 transforming growth factor beta1 activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036364 latent-TGF-beta1 activation|TGF-beta 1 activation|TGFB1 activation|L-TGF-beta 1 activation|TGFbeta 1 activation|transforming growth factor-beta1 activation The release of transforming growth factor beta1 (TGF-beta1) from its latent state. CHEBI:75833 (8E,10S,12Z)-10-hydroperoxyoctadeca-8,12-dienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75833 CHEBI:51867 methyl ketone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51867 CHEBI:75831 (8E,10S)-10-hydroperoxy-8-octadecenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75831 CHEBI:51869 alpha-diketone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51869 CHEBI:75837 phytyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75837 CHEBI:75838 phytyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75838 GO:0120178 steroid hormone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120178 The chemical reactions and pathways resulting in the formation of any steroid hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone. GO:0120179 adherens junction disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120179 The disaggregation of an adherens junction into its constituent components. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments. CHEBI:36223 thiomorpholinemonocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36223 GO:0120174 stress-induced homeostatically regulated protein degradation pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120174 SHRED pathway A stress-inducible protein catabolic pathway that promotes protein quality control by accelerating the degradation of misfolded ER membrane and cytosolic proteins, as well as native proteins. The pathway starts with the activation, by stress, of the Nma111p/Ynm3p serine protease, which cleaves the stress-induced hydrophilin Roq1p, resulting in the generation of a Roq1p cleavage product that selectively interacts with Ubr1p, an E3 ubiquitin ligase. Interaction with the Ubr1p type-1 substrate binding site reprograms the substrate specificity of this ubiquitin ligase resulting in the selective proteasome-mediated degradation of misfolded and native proteins. The pathway ends with degradation of the protein by the cytoplasmic proteasome. Currently, NMA111, ROQ1, UBR1, RAD6, and CDC48 are considered to be involved in this quality control pathway. GO:0120175 regulation of torso signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120175 Any process that modulates the frequency, rate or extent of the torso signaling pathway. GO:0120176 positive regulation of torso signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120176 Any process that activates or increases the frequency, rate or extent of the torso signaling pathway. GO:0120177 negative regulation of torso signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120177 Any process that stops, prevents, or reduces the frequency, rate or extent of the torso signaling pathway. GO:0120170 intraciliary transport particle B binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120170 intraflagellar transport particle B binding|intraflagellar transport complex B binding|IFT B complex binding|intraciliary transport complex B binding Interacting selectively and non-covalently with an intraciliary transport particle B (IFT B) complex. GO:0120171 Cdc24p-Far1p-Gbetagamma complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120171 ComplexPortal:CPX-977 Cdc24p-Far1p-BG complex|CDC24-FAR1-Gbetagamma complex|CDC24-FAR1-BG complex A complex that forms at the cell cortex in response to pheromone treatment and is required for the polarized growth of haploid yeast cells towards a mating partner during yeast mating. In the yeast Saccharomyces cerevisiae, this complex consists of Cdc24p, Far1p, Ste4p (G-protein beta subunit) and Ste18p (G-protein gamma subunit). CHEBI:51860 dexmethylphenidate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51860 GO:0120172 positive regulation of actin filament bundle convergence involved in mitotic contractile ring assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120172 Any process that activates or increases the frequency, rate or extent of actin filament bundle convergence involved in mitotic contractile ring assembly. GO:0120173 regulation of actin filament bundle convergence involved in mitotic contractile ring assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120173 Any process that modulates the frequency, rate or extent of actin filament bundle convergence involved in mitotic contractile ring assembly. CHEBI:75844 1,2,3-trilinoleoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75844 CHEBI:75845 1,2,3-trilinolenoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75845 CHEBI:51856 methylphenidate(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_51856 CHEBI:51857 methyl (S)-phenyl[(S)-piperidin-2-yl]acetate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51857 CHEBI:51851 ketonitrile biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51851 CHEBI:75848 1,2-dioleoyl-3-palmitoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75848 CHEBI:75849 1,3-dipalmitoleoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75849 CHEBI:51852 alpha-ketonitrile biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51852 CHEBI:75846 1,3-dioleoyl-2-palmitoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75846 CHEBI:51853 benzoyl cyanide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_51853 CHEBI:75847 1-palmitoyl-2,3-dioleoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75847 CHEBI:61200 3-decenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61200 GO:0120189 positive regulation of bile acid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120189 Any process that activates or increases the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue. CHEBI:36237 cholanic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36237 CHEBI:61204 docosapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61204 CHEBI:61201 beta-D-GlcA-(1->2)-alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-1-diphospho-ditrans,polycis-undecaprenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61201 CHEBI:36234 chenodeoxycholate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36234 CHEBI:36235 bile acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36235 GO:0120185 MBF transcription complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120185 MBF complex assembly|DSC1 transcription factor complex assembly|Mlu1-box binding factor assembly The aggregation, arrangement and bonding together of a set of components to form an MBF transcription complex. GO:0120186 negative regulation of protein localization to chromatin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120186 negative regulation of protein localisation to chromatin Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to chromatin. GO:0120187 positive regulation of protein localization to chromatin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120187 positive regulation of protein localisation to chromatin Any process that activates or increases the frequency, rate or extent of protein localization to chromatin. CHEBI:61205 docosatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61205 CHEBI:36238 5beta-cholanic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36238 GO:0120188 regulation of bile acid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120188 Any process that modulates the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue. GO:0120181 focal adhesion disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120181 The disaggregation of a focal adhesion into its constituent components. A focal adhesion is a complex of intracellular signaling and structural proteins that provides a structural link between the internal actin cytoskeleton and the ECM, and also functions as a locus of signal transduction activity. GO:0120182 regulation of focal adhesion disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120182 Any process that modulates the frequency, rate or extent of disaggregation of a focal adhesion into its constituent components. GO:0120183 positive regulation of focal adhesion disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120183 Any process that activates or increases the frequency, rate or extent of disaggregation of a focal adhesion into its constituent components. GO:0120184 negative regulation of focal adhesion disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120184 Any process that stops, prevents, or reduces the frequency, rate or extent of a focal adhesion into its constituent components. CHEBI:75840 2-keto-3-deoxy-L-galactonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75840 CHEBI:36232 icosa-5,7,11,14-tetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36232 CHEBI:75841 1,2,3-tripalmitoleoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75841 CHEBI:36233 disaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36233 GO:0120180 cell-substrate junction disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120180 The disaggregation of a cell-substrate junction into its constituent components. CHEBI:26888 tetrachlorobenzene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26888 CHEBI:75855 2,3-dilinolenoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75855 CHEBI:75856 3-methylfumaryl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75856 CHEBI:75853 2,3-dipalmitoleoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75853 CHEBI:75854 2,3-dilinoleoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75854 CHEBI:51847 ketoester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51847 CHEBI:51848 alpha-ketoester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51848 CHEBI:61211 beta-D-Man-(1->4)-beta-D-GlcA-(1->2)-alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-1-diphospho-ditrans,polycis-undecaprenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61211 CHEBI:51849 beta-ketoester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51849 CHEBI:36203 trioxilin A3 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36203 CHEBI:36204 12-hydroxylaurate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36204 CHEBI:36201 trioxilin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36201 CHEBI:36202 all-cis-icosa-5,8,14-trienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36202 GO:0120196 negative regulation of anther dehiscence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120196 Any process that stops, prevents, or reduces the frequency, rate or extent of anther dehiscence. GO:0120197 mucociliary clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120197 mucociliary transport|MCT|MCC The respiratory system process driven by motile cilia on epithelial cells of the respiratory tract by which mucus and associated inhaled particles and pathogens trapped within it are moved out of the airways. CHEBI:36208 shikimate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36208 GO:0120198 positive regulation of imaginal disc-derived wing size biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120198 Any process that increases the size of an imaginal disc-derived wing. CHEBI:61216 ditrans,polycis-undecaprenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61216 CHEBI:36205 cyclobutanedicarboxylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36205 GO:0120199 cone photoreceptor outer segment biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120199 The outer segment of a vertebrate cone photoreceptor that contains membrane discs that are contiguous with the ciliary membrane and containing opsin photoreceptor proteins. CHEBI:36206 3-hydroxylauric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36206 GO:0120192 tight junction assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120192 occluding junction assembly|occluding cell junction assembly A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other. GO:0120193 tight junction organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120193 occluding junction organization|occluding cell junction organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other. GO:0120194 regulation of anther dehiscence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120194 Any process involved in the dehiscence of an anther to release the pollen grains contained within it. GO:0120195 positive regulation of anther dehiscence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120195 Any process that activates or increases the frequency, rate or extent of anther dehiscence. CHEBI:75851 (2S,3R)-capreomycidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75851 CHEBI:36200 hepoxilin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36200 CHEBI:75852 1,3-dilinolenoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75852 GO:0120190 negative regulation of bile acid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120190 Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue. GO:0120191 negative regulation of termination of RNA polymerase II transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120191 repression of termination of RNA polymerase II transcription|down-regulation of RNA 3'-end formation by RNA polymerase II|negative regulation of RNA 3'-end formation by RNA polymerase II|downregulation of transcription termination from RNA polymerase II promoter|downregulation of transcription termination from Pol II promoter|down regulation of RNA polymerase II transcription termination|down regulation of transcription termination from Pol II promoter|down-regulation of termination of RNA polymerase II transcription|repression of transcription termination from RNA polymerase II promoter|downregulation of RNA polymerase II transcription termination|negative regulation of transcription termination from RNA polymerase II promoter|down regulation of RNA polymerase II transcription termination factor activity|down-regulation of transcription termination from RNA polymerase II promoter|downregulation of RNA polymerase II transcription termination factor activity|repression of RNA polymerase II transcription termination|repression of transcription termination from Pol II promoter|downregulation of termination of RNA polymerase II transcription|down regulation of RNA 3'-end formation by RNA polymerase II|down-regulation of RNA polymerase II transcription termination|negative regulation of RNA polymerase II transcription termination|down regulation of termination of RNA polymerase II transcription|downregulation of RNA 3'-end formation by RNA polymerase II|negative regulation of RNA polymerase II transcription termination factor activity|down-regulation of RNA polymerase II transcription termination factor activity|negative regulation of transcription termination from Pol II promoter|down-regulation of transcription termination from Pol II promoter|repression of RNA polymerase II transcription termination factor activity|repression of RNA 3'-end formation by RNA polymerase II|down regulation of transcription termination from RNA polymerase II promoter Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase II transcription. CHEBI:75850 1,3-dilinoleoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75850 CHEBI:51833 beta-D-fructofuranosyl alpha-D-mannopyranoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_51833 CHEBI:75867 1-oleoyl-3-palmitoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75867 CHEBI:51834 beta-D-fructofuranosyl alpha-D-mannopyranoside 6(F)-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51834 CHEBI:51835 microthecin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_51835 CHEBI:75865 D-glucosaminic acid 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75865 CHEBI:51836 3,3'-biflaviolin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51836 CHEBI:26895 tetracyclines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26895 CHEBI:75868 1-palmitoyl-3-oleoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75868 CHEBI:75869 1-oleoyl-3-palmitoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75869 CHEBI:26893 tetracyclic triterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26893 CHEBI:51837 3,8'-biflaviolin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51837 CHEBI:36218 beta-lactose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36218 CHEBI:36219 alpha-lactose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36219 CHEBI:12266 8-amino-7-oxononanoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_12266 CHEBI:61227 beta-D-GlcA-(1->2)-alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-1-diphospho-ditrans,polycis-undecaprenol(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61227 CHEBI:36210 (S)-3-hydroxylauric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36210 CHEBI:36211 2-hydroxydodecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36211 CHEBI:75860 (3R)-citramalyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75860 CHEBI:51822 3,7-dideoxy-D-threo-hepto-2,6-diuolosonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51822 CHEBI:51824 N-(3-aminopropyl)-4-aminobutanal biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51824 CHEBI:75876 (3R,4R)-3,4-dihydroxycyclohexa-1,5-diene-1-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75876 CHEBI:26863 teasterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_26863 CHEBI:75879 4-O-(beta-L-Araf-(1->2)-beta-L-Araf-(1->2)-beta-L-Araf)-cis-L-Hyp zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75879 GO:0120138 regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120138 Any process that modulates the frequency, rate or extent of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity. CHEBI:61232 N-acylphosphatidylethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61232 GO:0120139 positive regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120139 Any process that activates or increases the frequency, rate or extent of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity. CHEBI:61233 spermidine hydroxycinnamic acid conjugate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61233 CHEBI:85200 N-icosenoylsphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85200 CHEBI:61230 beta-D-Man-(1->4)-beta-D-GlcA-(1->2)-alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-1-diphospho-ditrans,polycis-undecaprenol(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61230 CHEBI:85201 N-icosenoylphytosphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85201 CHEBI:61231 L-seryl-AMP(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61231 GO:0120134 proximal portion of axoneme biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120134 proximal part of axoneme The portion of the axoneme that is close to the base of the cilium. GO:0120135 distal portion of axoneme biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120135 distal part of axoneme The portion of the axoneme that is close to the tip of the cilium. CHEBI:85204 N-oleoylphytosphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85204 GO:0120136 dUMP kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120136 deoxyuridine monophosphate kinase activity|ATP:dUMP phosphotransferase activity|dUMP-kinase activity Catalysis of the reaction: ATP + dUMP = ADP + dUDP. CHEBI:85205 3-hydroxytetradecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85205 GO:0120137 positive regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120137 Any process that activates or increases the frequency or rate of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity. CHEBI:85206 N-arachidonoylsphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85206 CHEBI:85207 N-arachidonoylphytosphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85207 CHEBI:85208 12-hydroxyoctadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85208 GO:0120132 positive regulation of apoptotic process in bone marrow cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120132 positive regulation of bone marrow cell programmed cell death by apoptosis|positive regulation of bone marrow cell apoptosis|positive regulation of killing of bone marrow cells|activation of apoptosis in bone marrow|positive regulation of apoptotic process in bone marrow|up-regulation of apoptosis in bone marrow|up regulation of apoptosis in bone marrow|positive regulation of programmed cell death, bone marrow cells|positive regulation of apoptosis in bone marrow|positive regulation of programmed cell death of bone marrow cells by apoptosis|upregulation of apoptosis in bone marrow Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process in the bone marrow. CHEBI:85209 12-hydroxyoctadecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85209 GO:0120133 negative regulation of actin cortical patch assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120133 downregulation of actin cortical patch assembly|down-regulation of actin cortical patch assembly|inhibition of actin cortical patch assembly|down regulation of actin cortical patch assembly Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin cortical patches. CHEBI:75870 2-palmitoyl-3-oleoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75870 CHEBI:26878 tertiary alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_26878 CHEBI:26873 terpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26873 CHEBI:26874 terpenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26874 CHEBI:26875 terpenyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26875 CHEBI:26876 terpineol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26876 CHEBI:61240 beta-D-Glc-(1->4)-alpha-D-Glc-1-diphospho-ditrans,polycis-undecaprenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61240 CHEBI:26872 terpene ketone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26872 GO:0120149 host cell peroxisome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120149 host peroxisome A small host cell organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism. CHEBI:61243 beta-D-Galp-(1->3)-beta-D-GalpNAc biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61243 GO:0120145 protein localization to basal ectoplasmic specialization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120145 protein localisation in basal ectoplasmic specialization|protein localization in basal ectoplasmic specialization|protein localisation to basal ectoplasmic specialization A process in which a protein is transported to, or maintained in, a location within a basal ectoplasmic specialization. CHEBI:61247 beta-D-Glc-(1->4)-alpha-D-Glc-1-diphospho-ditrans,polycis-undecaprenol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61247 GO:0120146 sulfatide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120146 sulfated galactocerebroside binding|3-O-sulfogalactosylceramide binding|SM4 binding Interacting selectively and non-covalently with sulfatide, also known as 3-O-sulfogalactosylceramide, SM4, or sulfated galactocerebroside. Sulfatide is a class of sulfoglycolipid, which are glycolipids that contain a sulfate group. GO:0120147 Formylglycine-generating oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120147 MetaCyc:RXN-16226|EC:1.8.3.7|RHEA:51152 Catalysis of the reaction: A [sulfatase]-L-cysteine + O(2) + 2 a thiol = a [sulfatase]-3-oxo-L-alanine + hydrogen sulfide + a disulfide + H(2)O. GO:0120148 host cell centrosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120148 host centrosome A structure in a host cell comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle. CHEBI:61246 beta-D-Galp-(1->3)-beta-D-GlcpNAc biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61246 GO:0120141 regulation of ecdysone receptor-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120141 Any process that modulates the frequency, rate or extent of the activity of any ecdysone receptor-mediated signaling pathway. GO:0120142 positive regulation of ecdysone receptor-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120142 Any process that activates or increases the frequency, rate or extent of any ecdysone receptor-mediated signaling pathway. GO:0120143 negative regulation of ecdysone receptor-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120143 Any process that stops, prevents, or reduces the frequency, rate or extent of any ecdysone receptor-mediated signaling pathway. CHEBI:61249 hesperetin(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61249 CHEBI:75880 4-O-(beta-L-Araf)-cis-L-Hyp zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75880 GO:0120140 negative regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120140 Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity. CHEBI:75884 N-acylindole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75884 CHEBI:75885 2-pyranones biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75885 CHEBI:75882 1-alkyl-2-acetylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75882 CHEBI:75883 monoalkylglycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75883 CHEBI:26845 tagaturonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26845 CHEBI:51802 4H-imidazole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_51802 CHEBI:26847 altraric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26847 CHEBI:26841 synthetic auxin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26841 CHEBI:61251 alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-1-diphospho-ditrans,polycis-undecaprenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61251 CHEBI:85220 N-acetyl-D-methionine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85220 CHEBI:61254 alpha-D-glucosyl ditrans,polycis-undecaprenyl diphosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61254 CHEBI:85221 N-icosanoyl-1-oleoyl-sn-glycero-3-phosphoethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85221 CHEBI:85222 N,1-dioleoyl-sn-glycero-3-phosphoethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85222 CHEBI:85223 N-arachidonoyl-1-oleoyl-sn-glycero-3-phosphoethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85223 CHEBI:61252 alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-1-diphospho-ditrans,polycis-undecaprenol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61252 CHEBI:61253 alpha-D-glucosyl ditrans,polycis-undecaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61253 CHEBI:85225 N-acyl-sn-glycero-3-phosphoethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85225 GO:0120157 PAR polarity complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120157 ComplexPortal:CPX-3462 PAR6-PAR3-aPKC complex|BEM1-CDC24-CLA4 complex|PAR3-PAR6-atypical PKC|Cdc42p GEF-PAK complex|apical polarity complex|PAR3/PAR6/aPKC A protein kinase complex that is required for the establishment of a cell polarity axis during the cell division cycle. Binds directly to activated CDC42 GTPase and is required for orchestrating a cellular gradient of CDC42. In S. cerevisiae components are: BEM1, CDC24 and CLA4; from worms to vertebrates it contains a PAR6 protein, PAR3 protein and an atypical PKC. CHEBI:85226 N-hexadecanoyl-sn-glycero-3-phosphoethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85226 GO:0120158 positive regulation of collagen catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120158 up-regulation of collagen catabolic process|activation of collagen catabolic process|positive regulation of collagen degradation|positive regulation of collagen catabolism|positive regulation of collagen breakdown|up regulation of collagen catabolic process|upregulation of collagen catabolic process Any process that activates or increases the frequency, rate or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix. CHEBI:85227 N-octadecanoyl-sn-glycero-3-phosphoethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85227 GO:0120159 rRNA pseudouridine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120159 EC:5.4.99.19|EC:5.4.99.29|EC:5.4.99.24|EC:5.4.99.23|EC:5.4.99.22|EC:5.4.99.43|EC:5.4.99.21|EC:5.4.99.20 23S rRNA pseudouridine(2605) synthase|23S rRNA pseudouridine(1911/1915/1917) synthase|23S rRNA pseudouridine(2604) synthase|23S rRNA pseudouridine(2457) synthase|16S rRNA pseudouridine(516) synthase|23S rRNA pseudouridine(746) synthase|21S rRNA pseudouridine(2819) synthase|23S rRNA pseudouridine(955/2504/2580) synthase Catalysis of the reaction: an rRNA uridine = an rRNA pseudouridine. Conversion of uridine in an rRNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5. CHEBI:85228 N-icosanoyl-sn-glycero-3-phosphoethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85228 GO:0120152 calcium-dependent outer dynein arm binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120152 Interacting selectively and non-covalently with an outer dynein arm in the presence of calcium. CHEBI:85229 N-oleoyl-sn-glycero-3-phosphoethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85229 GO:0120153 calcium-dependent carbohydrate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120153 Interacting selectively and non-covalently with any carbohydrate in the presence of calcium. GO:0120154 negative regulation of ERBB4 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120154 Any process that stops, prevents or reduces the frequency, rate or extent of ERBB4 signaling pathway. GO:0120155 MIH complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120155 Mlc1p-Iqg1p-Hof1p complex A trimeric complex involved in cytokinesis. Proposed to bridge actomyosin ring contraction and septum synthesis in yeast, resulting in the coordination of these processes, and leading to plasma membrane ingression and fusion. In the yeast Saccharomyces cerevisiae this complex consists of Mlc1p, Iqg1p and Hof1p proteins. GO:0120150 regulation of mitotic actomyosin contractile ring disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120150 regulation of mitotic cytokinetic ring disassembly|regulation of mitotic actomyosin ring disassembly|regulation of mitotic CAR disassembly|regulation of mitotic constriction ring disassembly|regulation of mitotic contractile actomyosin ring disassembly Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring disassembly. GO:0120151 positive regulation of mitotic actomyosin contractile ring disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120151 positive regulation of mitotic actomyosin ring disassembly|positive regulation of mitotic CAR disassembly|positive regulation of mitotic constriction ring disassembly|positive regulation of mitotic cytokinetic ring disassembly|positive regulation of mitotic contractile actomyosin ring disassembly Any process that activates or increases the frequency, rate or extent of mitotic actomyosin contractile ring disassembly. CHEBI:75890 1,2-diacyl-sn-glycero-3-phospho-1'-(3'-O-L-alanyl)-sn-glycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75890 CHEBI:75895 N(alpha)-methyl-L-histidine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75895 CHEBI:26848 tannin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26848 CHEBI:26849 tartaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26849 CHEBI:75894 4-O-(beta-L-Araf-(1->2)-beta-L-Araf-(1->2)-beta-L-Araf)-cis-L-Hyp biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75894 CHEBI:85210 N-acetyl-D-methionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85210 CHEBI:61265 (beta-D-glucopyranosyloxymethyl)deoxyuridine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61265 CHEBI:85211 15-hydroxypentadecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85211 CHEBI:61266 hemicellulose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61266 CHEBI:85212 omega-hydroxy fatty acyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85212 CHEBI:61264 pectic arabinan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61264 CHEBI:85213 16-hydroxyhexadecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85213 CHEBI:85214 9-decenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85214 CHEBI:61269 scopolamine(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61269 GO:0120168 detection of hot stimulus involved in thermoception biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120168 thermoception, sensory detection of heat stimulus|thermoception, sensory transduction of heat stimulus|sensory transduction of hot stimulus during thermoception|thermoception, sensory transduction of hot stimulus|thermoception, sensory detection of hot stimulus|sensory detection of hot stimulus during thermoception|sensory detection of heat stimulus during thermoception|sensory transduction of heat stimulus during thermoception The series of events in which a hot stimulus is received and converted into a molecular signal as part of thermoception. CHEBI:85215 1-myristoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85215 GO:0120169 detection of cold stimulus involved in thermoception biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120169 sensory detection of cold stimulus during thermoception|sensory transduction of cold stimulus during thermoception|thermoception, sensory detection of cold stimulus|thermoception, sensory transduction of cold stimulus The series of events in which a cold stimulus is received and converted into a molecular signal as part of thermoception. CHEBI:85216 N-acyllysophosphatidylethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85216 CHEBI:61267 5-nitroanthranilate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61267 CHEBI:85217 N-palmitoyl-1-oleoyl-sn-glycero-3-phosphoethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85217 CHEBI:61268 5-nitrosalicylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61268 GO:0120163 negative regulation of cold-induced thermogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120163 negative regulation of CIT Any process that stops, prevents, or reduces the rate of cold-induced thermogenesis. GO:0120164 conidium germination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120164 The physiological and developmental changes that occur in a conidium or asexual spore following release from dormancy up to the earliest signs of development such as swelling of conidia, adhesion and nuclear decondensation followed by hyphal growth several hours later. In many genera of plant pathogenic fungi (e.g. Magnaporthe, Colletotrichum, Ustilago), swelling of the hyphal tips to form appressorium, metabolic activities including respiration, RNA and protein synthesis and trehalose breakdown and changes in cell wall composition can be detected in conidium germination. CHEBI:85219 N-stearoyl-1-oleoyl-sn-glycero-3-phosphoethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85219 GO:0120165 perithecium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120165 The process whose specific outcome is the progression of a perithecium over time, from its formation to the mature structure. Peritheicum is a flask-shaped fruiting body of certain molds and ascomycetous fungi having a pore for the escape of spores. In the ascomycetous fungi such as Neurospora crassa and Sordaria macrospora, these perithecia are formed in the sexual phase and they discharge ascospores through the ostiolum at the tip of the perithecial neck. GO:0120166 protoperithecium formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120166 The process of producing fruiting body precursors, called protoperithecia. Protoperitheicium is a spherical structure that is formed in the sexual phase of ascomycetous fungi such as Neurospora crassa and Sordaria macrospora. Protoperithecium is formed by the enveloping of ascogonia cells by sterile hyphae and it develops into perithecium. GO:0120160 intraciliary transport particle A binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120160 intraflagellar transport complex A binding|IFT A complex binding|intraciliary transport complex A binding|intraflagellar transport particle A binding Interacting selectively and non-covalently with an intraciliary transport particle A (IFT A) complex. GO:0120161 regulation of cold-induced thermogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120161 regulation of CIT Any process that modulates the frequency, rate or extent of cold-induced thermogenesis. GO:0120162 positive regulation of cold-induced thermogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120162 positive regulation of CIT Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis. GO:0036516 chemoattraction of dopaminergic neuron axon biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036516 chemoattraction of DA axon|chemoattraction of dopaminergic axon The process in which a dopaminergic neuron growth cone is directed to a specific target site in response to an attractive chemical signal. GO:0036517 chemoattraction of serotonergic neuron axon biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036517 chemoattraction of serotonergic axon|chemoattraction of 5-HT axon The process in which a serotonergic neuron growth cone is directed to a specific target site in response to an attractive chemical signal. GO:1901048 transforming growth factor beta receptor signaling pathway involved in regulation of multicellular organism growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901048 TGF-beta receptor signalling pathway of regulation of multicellular organism growth|TGF-beta receptor signaling pathway of regulation of multicellular organism growth|TGFbeta receptor signaling pathway of regulation of body size|transforming growth factor beta receptor signalling pathway of regulation of body size|TGFbeta receptor signaling pathway of regulation of multicellular organism growth|transforming growth factor beta receptor signalling pathway of regulation of multicellular organism growth|transforming growth factor beta receptor signaling pathway of regulation of body growth|TGFbeta receptor signalling pathway of regulation of body growth|transforming growth factor beta receptor signaling pathway of regulation of body size|TGFbeta receptor signalling pathway of regulation of body size|TGF-beta receptor signaling pathway of regulation of body growth|TGF-beta receptor signalling pathway of regulation of body growth|transforming growth factor beta receptor signaling pathway of regulation of multicellular organism growth|TGF-beta receptor signalling pathway of regulation of body size|TGFbeta receptor signalling pathway of regulation of multicellular organism growth|TGF-beta receptor signaling pathway of regulation of body size|TGFbeta receptor signaling pathway of regulation of body growth|transforming growth factor beta receptor signalling pathway of regulation of body growth A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription, that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size. GO:0036518 chemorepulsion of dopaminergic neuron axon biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036518 chemorepulsion of DA axon|chemorepulsion of dopaminergic axon The process in which a dopaminergic neuron growth cone is directed to a specific target site in response to a repulsive chemical cue. GO:1901049 atropine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901049 atropine metabolism The chemical reactions and pathways involving atropine. GO:0036519 chemorepulsion of serotonergic neuron axon biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036519 chemorepulsion of serotonergic axon|chemorepulsion of 5-HT axon The process in which a serotonergic neuron growth cone is directed to a specific target site in response to a repulsive chemical cue. GO:1901046 positive regulation of oviposition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901046 positive regulation of egg laying|up regulation of egg laying|up-regulation of oviposition|up-regulation of egg-laying|upregulation of oviposition|upregulation of egg laying|activation of egg-laying|positive regulation of egg-laying|up regulation of egg-laying|up-regulation of egg laying|up regulation of oviposition|activation of oviposition|activation of egg laying|upregulation of egg-laying Any process that activates or increases the frequency, rate or extent of oviposition. GO:1901047 insulin receptor signaling pathway involved in determination of adult lifespan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901047 daf-2 receptor signaling pathway of determination of adult lifespan|insulin receptor signalling pathway of determination of adult lifespan|insulin receptor signaling pathway of determination of adult lifespan The series of molecular signals generated as a consequence of the insulin receptor binding to insulin that controls viability and duration in the adult phase of the life-cycle. GO:1901044 protein polyubiquitination involved in nucleus-associated proteasomal ubiquitin-dependent protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901044 Any protein polyubiquitination that is involved in nucleus-associated proteasomal ubiquitin-dependent protein catabolic process. GO:1901045 negative regulation of oviposition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901045 inhibition of oviposition|inhibition of egg-laying|downregulation of egg laying|down regulation of egg laying|down regulation of oviposition|down-regulation of egg-laying|negative regulation of egg-laying|inhibition of egg laying|downregulation of oviposition|downregulation of egg-laying|down-regulation of oviposition|down regulation of egg-laying|down-regulation of egg laying|negative regulation of egg laying Any process that stops, prevents or reduces the frequency, rate or extent of oviposition. GO:1901053 sarcosine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901053 sarcosine catabolism|sarcosine degradation|sarcosine breakdown The chemical reactions and pathways resulting in the breakdown of sarcosine. GO:1901054 sarcosine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901054 sarcosine anabolism|sarcosine synthesis|sarcosine biosynthesis|sarcosine formation The chemical reactions and pathways resulting in the formation of sarcosine. GO:1901051 atropine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901051 atropine formation|atropine biosynthesis|atropine anabolism|atropine synthesis The chemical reactions and pathways resulting in the formation of atropine. GO:0036510 trimming of terminal mannose on C branch biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036510 conversion of (Man)9(GlcNAc)2 to (Man)8C(GlcNAc)2|glycoprotein mannose trimming on C branch|conversion of M9 to M8C The removal of an alpha-1,2-linked mannose from the C-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum. GO:0036511 trimming of first mannose on A branch biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036511 conversion of (Man)9(GlcNAc)2 to (Man)8A(GlcNAc)2|conversion of M9 to M8A|glycoprotein mannose trimming on A branch The removal of the first alpha-1,2-linked mannose from the A-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum. GO:1901052 sarcosine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901052 sarcosine metabolism The chemical reactions and pathways involving sarcosine. GO:0036512 trimming of second mannose on A branch biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036512 conversion of (Man)8A(GlcNAc)2 to (Man)7AA(GlcNAc)2|conversion of M8A to M7AA|glycoprotein mannose trimming on A branch The removal of the second alpha-1,2-linked mannose from the A-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum. GO:0036513 Derlin-1 retrotranslocation complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036513 Derlin-1 protein dislocation complex|Derlin-1 complex|ERAD protein dislocation complex|Derlin-1 retro-translocation complex|Derlin-1 retrotranslocon A protein complex that functions in the retrotranslocation step of ERAD (ER-associated protein degradation), and includes at its core Derlin-1 oligomers forming a retrotranslocation channel. GO:1901050 atropine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901050 atropine catabolism|atropine degradation|atropine breakdown The chemical reactions and pathways resulting in the breakdown of atropine. GO:0036514 dopaminergic neuron axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036514 mdDA axon guidance|dopaminergic axon guidance|DA axon guidance The chemotaxis process that directs the migration of an axon growth cone of a dopaminergic neuron to a specific target site in response to a combination of attractive and repulsive cues. GO:0036515 serotonergic neuron axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036515 5-HT axon guidance|serotonergic axon guidance The chemotaxis process that directs the migration of an axon growth cone of a serotonergic neuron to a specific target site in response to a combination of attractive and repulsive cues. GO:0036505 prosaposin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036505 prosaposin-activated receptor activity Combining with prosaposin to initiate a change in cell activity. Prosaposin is the glycoprotein precursor of four cleavage products (saposins A, B, C and D). GO:0036506 maintenance of unfolded protein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036506 Maintaining a protein in an unfolded, soluble state. GO:0036507 protein demannosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036507 protein de-mannosylation The removal of one or more mannose residues from a mannosylated protein. GO:1901059 p-hydroxyphenyl lignin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901059 H-lignin catabolic process|p-hydroxyphenyl lignin catabolism|p-hydroxyphenyl lignin degradation|p-hydroxyphenyl lignin breakdown The chemical reactions and pathways resulting in the breakdown of p-hydroxyphenyl lignin. GO:0036508 protein alpha-1,2-demannosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036508 glycoprotein mannose trimming|mannose trimming The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein. GO:1901057 trimethylenediamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901057 trimethylenediamine anabolism|trimethylenediamine synthesis|trimethylenediamine biosynthesis|trimethylenediamine formation The chemical reactions and pathways resulting in the formation of trimethylenediamine. GO:0036509 trimming of terminal mannose on B branch biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036509 KEGG_REACTION:R06722 glycoprotein mannose trimming on B branch|conversion of (Man)9(GlcNAc)2 to (Man)8B(GlcNAc)2|conversion of M9 to M8B The removal of an alpha-1,2-linked mannose from the B-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum. GO:1901058 p-hydroxyphenyl lignin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901058 H-lignin metabolic process|p-hydroxyphenyl lignin metabolism The chemical reactions and pathways involving p-hydroxyphenyl lignin. GO:1901055 trimethylenediamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901055 trimethylenediamine metabolism The chemical reactions and pathways involving trimethylenediamine. GO:1901056 trimethylenediamine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901056 trimethylenediamine catabolism|trimethylenediamine degradation|trimethylenediamine breakdown The chemical reactions and pathways resulting in the breakdown of trimethylenediamine. GO:1901064 syringal lignin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901064 syringal lignin metabolism|S-lignin metabolic process The chemical reactions and pathways involving syringal lignin. CHEBI:131561 hyaluronic acid synthesis inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131561 GO:1901065 syringal lignin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901065 syringal lignin degradation|syringal lignin breakdown|syringal lignin catabolism|S-lignin catabolic process The chemical reactions and pathways resulting in the breakdown of syringal lignin. CHEBI:131562 (5S,15S)-5-hydroperoxy-15-HETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131562 GO:1901062 guaiacyl lignin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901062 guaiacyl lignin breakdown|guaiacyl lignin catabolism|G-lignin catabolic process|guaiacyl lignin degradation The chemical reactions and pathways resulting in the breakdown of guaiacyl lignin. GO:0036500 ATF6-mediated unfolded protein response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036500 UPR signaling by ATF6 stress sensor|ATF6 signaling in response to endoplasmic reticulum stress|ATF6-alpha UPR branch|ATF6 signal transduction pathway|ATF6-beta UPR branch|endoplasmic reticulum unfolded protein response; ATF6 signaling|ATF6 branch of UPR|activating transcription factor 6 signaling in unfolded protein response A series of molecular signals mediated by the endoplasmic reticulum membrane stress sensor ATF6 (activating transcription factor 6). Begins with activation of ATF6 in response to endoplasmic reticulum (ER) stress, and ends with regulation of a downstream cellular process, e.g. transcription. Under conditions of endoplasmic reticulum stress, ATF6 translocates to the Golgi where it is processed by proteases to release a cytoplasmic domain (ATF6f), which operates as a transcriptional activator of many genes required to restore folding capacity. GO:1901063 guaiacyl lignin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901063 G-lignin biosynthetic process|guaiacyl lignin anabolism|guaiacyl lignin synthesis|guaiacyl lignin formation|guaiacyl lignin biosynthesis The chemical reactions and pathways resulting in the formation of guaiacyl lignin. GO:1901060 p-hydroxyphenyl lignin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901060 p-hydroxyphenyl lignin anabolism|p-hydroxyphenyl lignin synthesis|p-hydroxyphenyl lignin formation|p-hydroxyphenyl lignin biosynthesis|H-lignin biosynthetic process The chemical reactions and pathways resulting in the formation of p-hydroxyphenyl lignin. GO:0036501 UFD1-NPL4 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036501 Ufd1/Npl4 complex|UFD1L-NPLOC4 complex|Npl4p-Ufd1p complex|Ufd1-Npl4 binary complex|Ufd1-Npl4 cofactor complex A dimeric protein complex that contains the co-factors for the ATPase VCP/p97 (Cdc48p in budding yeast). In mammals, this complex consists of UFD1L (UFD1) and NPLOC4 (NPL4). In budding yeast, the complex is a dimer of Ufd1p and Npl4p. CHEBI:131564 (5S,15S)-5-hydroperoxy-15-HETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131564 GO:1901061 guaiacyl lignin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901061 G-lignin metabolic process|guaiacyl lignin metabolism The chemical reactions and pathways involving guaiacyl lignin. GO:0036502 Derlin-1-VIMP complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036502 Derlin-1/VIMP complex A protein complex containing, in mammals, Derlin-1 and VCP-interacting membrane protein (VIMP). The complex links the p97/VCP-containing ATPase complex with Derlin-1 during translocation of protein substrates from the endoplasmic reticulum to the cytosol for degradation by the cytosolic proteasome. CHEBI:131565 steroid aldehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131565 GO:0036503 ERAD pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036503 protein degradation by ERAD|ER-associated degradation pathway|endoplasmic reticulum-associated degradation|endoplasmic reticulum-associated protein degradation pathway The protein catabolic pathway which targets endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. It begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein modifications necessary for correct substrate transfer (e.g. ubiquitination), transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome. GO:0036504 Golgi membrane fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036504 membrane fusion involved in Golgi reassembly|post-mitotic fusion of Golgi membranes The joining of two lipid bilayers that surround the Golgi apparatus to form a single Golgi membrane. GO:1901068 guanosine-containing compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901068 guanosines metabolism|guanosine-containing compound metabolism|guanosines metabolic process The chemical reactions and pathways involving guanosine-containing compounds (guanosines). GO:1901069 guanosine-containing compound catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901069 guanosines catabolism|guanosine-containing compound catabolism|guanosines degradation|guanosine-containing compound degradation|guanosines breakdown|guanosine-containing compound breakdown|guanosines catabolic process The chemical reactions and pathways resulting in the breakdown of guanosine-containing compounds (guanosines). GO:1901066 syringal lignin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901066 syringal lignin biosynthesis|syringal lignin anabolism|syringal lignin synthesis|syringal lignin formation|S-lignin biosynthetic process The chemical reactions and pathways resulting in the formation of syringal lignin. GO:1901067 ferulate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901067 ferulate degradation|ferulate breakdown|ferulate catabolism The chemical reactions and pathways resulting in the breakdown of ferulate. GO:1901075 negative regulation of engulfment of apoptotic cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901075 down regulation of engulfment of cell corpse|downregulation of engulfment of apoptotic cell corpse|downregulation of engulfment of cell corpse|downregulation of engulfment of apoptotic cell|down regulation of engulfment of apoptotic cell|down-regulation of engulfment of apoptotic cell corpse|negative regulation of engulfment of apoptotic cell corpse|inhibition of engulfment of apoptotic cell|negative regulation of engulfment of cell corpse|down-regulation of engulfment of cell corpse|inhibition of engulfment of apoptotic cell corpse|inhibition of engulfment of cell corpse|down-regulation of engulfment of apoptotic cell|down regulation of engulfment of apoptotic cell corpse Any process that stops, prevents or reduces the frequency, rate or extent of engulfment of apoptotic cell. GO:1901076 positive regulation of engulfment of apoptotic cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901076 up regulation of engulfment of apoptotic cell|up regulation of engulfment of apoptotic cell corpse|activation of engulfment of apoptotic cell corpse|positive regulation of engulfment of apoptotic cell corpse|up regulation of engulfment of cell corpse|activation of engulfment of cell corpse|positive regulation of engulfment of cell corpse|upregulation of engulfment of apoptotic cell|up-regulation of engulfment of apoptotic cell corpse|up-regulation of engulfment of cell corpse|activation of engulfment of apoptotic cell|up-regulation of engulfment of apoptotic cell|upregulation of engulfment of apoptotic cell corpse|upregulation of engulfment of cell corpse Any process that activates or increases the frequency, rate or extent of engulfment of apoptotic cell. GO:1901073 glucosamine-containing compound biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901073 glucosamines anabolism|glucosamines synthesis|glucosamines formation|glucosamine-containing compound anabolism|glucosamines biosynthetic process|glucosamine-containing compound synthesis|glucosamine-containing compound biosynthesis|glucosamine-containing compound formation|glucosamines biosynthesis The chemical reactions and pathways resulting in the formation of glucosamine-containing compounds (glucosamines). CHEBI:131530 pyridoxal(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131530 GO:1901074 regulation of engulfment of apoptotic cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901074 regulation of engulfment of cell corpse|regulation of engulfment of apoptotic cell corpse Any process that modulates the frequency, rate or extent of engulfment of apoptotic cell. GO:1901071 glucosamine-containing compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901071 glucosamines metabolic process|glucosamine-containing compound metabolism|glucosamines metabolism The chemical reactions and pathways involving glucosamine-containing compounds (glucosamines). GO:1901072 glucosamine-containing compound catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901072 glucosamine-containing compound breakdown|glucosamine-containing compound catabolism|glucosamines catabolic process|glucosamines degradation|glucosamines catabolism|glucosamines breakdown|glucosamine-containing compound degradation The chemical reactions and pathways resulting in the breakdown of glucosamine-containing compounds (glucosamines). CHEBI:131533 pyridoxamine(2+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131533 GO:1901070 guanosine-containing compound biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901070 guanosines anabolism|guanosine-containing compound anabolism|guanosines synthesis|guanosine-containing compound synthesis|guanosines formation|guanosine-containing compound formation|guanosines biosynthesis|guanosines biosynthetic process|guanosine-containing compound biosynthesis The chemical reactions and pathways resulting in the formation of guanosine-containing compounds (guanosines). CHEBI:36281 caffeic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36281 GO:1901079 positive regulation of relaxation of muscle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901079 upregulation of relaxation of muscle|up-regulation of relaxation of muscle|activation of relaxation of muscle|up regulation of relaxation of muscle Any process that activates or increases the frequency, rate or extent of relaxation of muscle. GO:1901077 regulation of relaxation of muscle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901077 Any process that modulates the frequency, rate or extent of relaxation of muscle. GO:1901078 negative regulation of relaxation of muscle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901078 down regulation of relaxation of muscle|inhibition of relaxation of muscle|down-regulation of relaxation of muscle|downregulation of relaxation of muscle Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of muscle. GO:1901086 benzylpenicillin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901086 penicillin G metabolism|benzylpenicillin metabolism The chemical reactions and pathways involving benzylpenicillin. GO:1901087 benzylpenicillin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901087 benzylpenicillin breakdown|penicillin G catabolism|penicillin G degradation|benzylpenicillin catabolism|penicillin G breakdown|penicillin G catabolic process|benzylpenicillin degradation The chemical reactions and pathways resulting in the breakdown of benzylpenicillin. GO:1901084 pyrrolizidine alkaloid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901084 pyrrolizidine alkaloid catabolism|pyrrolizidine alkaloid degradation|pyrrolizidine alkaloid breakdown The chemical reactions and pathways resulting in the breakdown of pyrrolizidine alkaloid. GO:1901085 pyrrolizidine alkaloid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901085 pyrrolizidine alkaloid biosynthesis|pyrrolizidine alkaloid anabolism|pyrrolizidine alkaloid synthesis|pyrrolizidine alkaloid formation The chemical reactions and pathways resulting in the formation of pyrrolizidine alkaloid. GO:1901082 positive regulation of relaxation of smooth muscle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901082 up regulation of relaxation of smooth muscle|positive regulation of smooth muscle relaxation|activation of relaxation of smooth muscle|up regulation of smooth muscle relaxation|up-regulation of relaxation of smooth muscle|upregulation of smooth muscle relaxation|up-regulation of smooth muscle relaxation|upregulation of relaxation of smooth muscle|activation of smooth muscle relaxation Any process that activates or increases the frequency, rate or extent of relaxation of smooth muscle. GO:1901083 pyrrolizidine alkaloid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901083 pyrrolizidine alkaloid metabolism The chemical reactions and pathways involving pyrrolizidine alkaloid. GO:1901080 regulation of relaxation of smooth muscle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901080 regulation of smooth muscle relaxation Any process that modulates the frequency, rate or extent of relaxation of smooth muscle. GO:1901081 negative regulation of relaxation of smooth muscle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901081 down-regulation of relaxation of smooth muscle|downregulation of smooth muscle relaxation|down regulation of smooth muscle relaxation|inhibition of relaxation of smooth muscle|inhibition of smooth muscle relaxation|down regulation of relaxation of smooth muscle|down-regulation of smooth muscle relaxation|negative regulation of smooth muscle relaxation|downregulation of relaxation of smooth muscle Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of smooth muscle. CHEBI:36299 tricarboxylic acid monoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36299 GO:0012505 endomembrane system biolink:CellularComponent go-plus goslim_flybase_ribbon|goslim_yeast|goslim_candida|goslim_aspergillus http://purl.obolibrary.org/obo/GO_0012505 Wikipedia:Endomembrane_system A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles. GO:0012506 vesicle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0012506 NIF_Subcellular:sao1153182838 The lipid bilayer surrounding any membrane-bounded vesicle in the cell. GO:0012503 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0012503 GO:0012504 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0012504 GO:0012509 inter-Golgi transport vesicle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0012509 inter-Golgi transport constitutive secretory pathway transport vesicle membrane The lipid bilayer surrounding a vesicle transporting substances within the Golgi. GO:0012507 ER to Golgi transport vesicle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0012507 ER-Golgi transport vesicle membrane|ER to Golgi constitutive secretory pathway transport vesicle membrane|endoplasmic reticulum-Golgi transport vesicle membrane|COPII coated vesicle membrane|endoplasmic reticulum to Golgi transport vesicle membrane The lipid bilayer surrounding a vesicle transporting substances from the endoplasmic reticulum to the Golgi. GO:1901088 benzylpenicillin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901088 penicillin G anabolism|penicillin G synthesis|benzylpenicillin anabolism|penicillin G formation|benzylpenicillin synthesis|benzylpenicillin biosynthesis|benzylpenicillin formation|penicillin G biosynthesis The chemical reactions and pathways resulting in the formation of benzylpenicillin. GO:0012508 Golgi to ER transport vesicle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0012508 Golgi-ER transport vesicle membrane|Golgi to ER constitutive secretory pathway transport vesicle membrane|Golgi to endoplasmic reticulum transport vesicle membrane|Golgi-endoplasmic reticulum transport vesicle membrane The lipid bilayer surrounding a vesicle transporting substances from the Golgi to the ER. GO:1901089 acetate ester metabolic process involved in fermentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901089 acetate ester metabolic process during fermentation Any acetate ester metabolic process that is involved in fermentation. GO:1901097 negative regulation of autophagosome maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901097 inhibition of amphisome-lysosome fusion|inhibition of autophagic vacuole fusion|inhibition of autophagosome maturation|inhibition of autolysosome formation|negative regulation of autophagic vacuole fusion|down-regulation of autophagic vacuole maturation|down regulation of amphisome-lysosome fusion|down-regulation of fusion of autophagosome with lysosome|negative regulation of fusion of autophagosome with lysosome|downregulation of amphisome-lysosome fusion|down regulation of autophagic vacuole fusion|inhibition of autophagic vacuole maturation|down-regulation of autophagosome maturation|negative regulation of autolysosome formation|down-regulation of autolysosome formation|negative regulation of autophagosome maturation|downregulation of autophagic vacuole fusion|negative regulation of autophagosome fusion|inhibition of fusion of autophagosome with lysosome|down-regulation of amphisome-lysosome fusion|negative regulation of amphisome-lysosome fusion|downregulation of autophagosome maturation|downregulation of autolysosome formation|down regulation of autophagic vacuole maturation|down regulation of fusion of autophagosome with lysosome|down-regulation of autophagic vacuole fusion|down regulation of autophagosome maturation|down regulation of autolysosome formation|downregulation of autophagic vacuole maturation|downregulation of fusion of autophagosome with lysosome Any process that stops, prevents or reduces the frequency, rate or extent of autophagosome maturation. GO:1901098 positive regulation of autophagosome maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901098 up regulation of autophagic vacuole maturation|up-regulation of autophagic vacuole fusion|up regulation of fusion of autophagosome with lysosome|activation of autophagic vacuole maturation|positive regulation of autophagic vacuole fusion|positive regulation of fusion of autophagosome with lysosome|upregulation of amphisome-lysosome fusion|up-regulation of autophagosome maturation|up-regulation of autolysosome formation|activation of fusion of autophagosome with lysosome|upregulation of autophagic vacuole fusion|activation of autolysosome formation|activation of autophagosome maturation|up-regulation of autophagic vacuole maturation|up regulation of amphisome-lysosome fusion|up-regulation of fusion of autophagosome with lysosome|positive regulation of amphisome-lysosome fusion|positive regulation of autolysosome formation|positive regulation of autophagosome maturation|up regulation of autophagosome maturation|up regulation of autophagic vacuole fusion|up regulation of autolysosome formation|activation of amphisome-lysosome fusion|upregulation of autophagic vacuole maturation|activation of autophagic vacuole fusion|positive regulation of autophagosome fusion|upregulation of fusion of autophagosome with lysosome|up-regulation of amphisome-lysosome fusion|upregulation of autophagosome maturation|upregulation of autolysosome formation Any process that activates or increases the frequency, rate or extent of autophagosome maturation. GO:1901095 positive regulation of protein homotetramerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901095 upregulation of protein homotetramer formation|upregulation of protein homotetramer assembly|upregulation of protein homotetramerization|up regulation of protein homotetramer biosynthetic process|up regulation of protein homotetramer biosynthesis|activation of protein homotetramer biosynthetic process|activation of protein homotetramer biosynthesis|positive regulation of protein homotetramer biosynthesis|up-regulation of protein homotetramer formation|activation of protein homotetramer formation|positive regulation of protein homotetramer biosynthetic process|up regulation of protein homotetramer assembly|activation of protein homotetramer assembly|positive regulation of protein homotetramer assembly|up regulation of protein homotetramerization|activation of protein homotetramerization|up-regulation of protein homotetramer biosynthesis|positive regulation of protein homotetramer formation|up-regulation of protein homotetramer biosynthetic process|up regulation of protein homotetramer formation|up-regulation of protein homotetramer assembly|up-regulation of protein homotetramerization|upregulation of protein homotetramer biosynthetic process|upregulation of protein homotetramer biosynthesis Any process that activates or increases the frequency, rate or extent of protein homotetramerization. CHEBI:36267 molybdenum oxoacid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36267 GO:1901096 regulation of autophagosome maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901096 regulation of amphisome-lysosome fusion|regulation of autolysosome formation|regulation of autophagosome maturation|regulation of autophagic vacuole fusion|regulation of fusion of autophagosome with lysosome|regulation of autophagosome fusion Any process that modulates the frequency, rate or extent of autophagosome maturation. GO:1901093 regulation of protein homotetramerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901093 regulation of protein homotetramer biosynthetic process|regulation of protein homotetramer biosynthesis|regulation of protein homotetramer assembly|regulation of protein homotetramer formation Any process that modulates the frequency, rate or extent of protein homotetramerization. GO:0012501 programmed cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0012501 Wikipedia:Programmed_cell_death non-apoptotic programmed cell death|caspase-independent cell death|caspase-independent apoptosis|RCD|regulated cell death|PCD|nonapoptotic programmed cell death A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell. GO:1901094 negative regulation of protein homotetramerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901094 down regulation of protein homotetramer biosynthetic process|down regulation of protein homotetramer biosynthesis|downregulation of protein homotetramer biosynthesis|downregulation of protein homotetramer biosynthetic process|down regulation of protein homotetramer assembly|down regulation of protein homotetramerization|downregulation of protein homotetramer assembly|downregulation of protein homotetramerization|down-regulation of protein homotetramer biosynthesis|negative regulation of protein homotetramer biosynthetic process|negative regulation of protein homotetramer biosynthesis|down-regulation of protein homotetramer biosynthetic process|negative regulation of protein homotetramer formation|down-regulation of protein homotetramer formation|negative regulation of protein homotetramer assembly|down-regulation of protein homotetramer assembly|inhibition of protein homotetramer biosynthesis|inhibition of protein homotetramer biosynthetic process|down-regulation of protein homotetramerization|downregulation of protein homotetramer formation|inhibition of protein homotetramer assembly|inhibition of protein homotetramerization|down regulation of protein homotetramer formation|inhibition of protein homotetramer formation Any process that stops, prevents or reduces the frequency, rate or extent of protein homotetramerization. GO:0012502 induction of programmed cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0012502 induction of nonapoptotic programmed cell death|induction of non-apoptotic programmed cell death A process which directly activates any of the steps required for programmed cell death. GO:1901091 negative regulation of protein tetramerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901091 downregulation of protein tetramer assembly|downregulation of protein tetramer formation|downregulation of protein tetramerization|down-regulation of protein tetramer biosynthesis|down-regulation of protein tetramer biosynthetic process|negative regulation of protein tetramer biosynthetic process|negative regulation of protein tetramer biosynthesis|down regulation of protein tetramer formation|inhibition of protein tetramer formation|inhibition of protein tetramer biosynthesis|inhibition of protein tetramer biosynthetic process|down-regulation of protein tetramer assembly|negative regulation of protein tetramer assembly|down-regulation of protein tetramerization|inhibition of protein tetramer assembly|inhibition of protein tetramerization|down regulation of protein tetramer biosynthesis|down regulation of protein tetramer biosynthetic process|negative regulation of protein tetramer formation|down-regulation of protein tetramer formation|downregulation of protein tetramer biosynthetic process|downregulation of protein tetramer biosynthesis|down regulation of protein tetramer assembly|down regulation of protein tetramerization Any process that stops, prevents or reduces the frequency, rate or extent of protein tetramerization. CHEBI:9209 soyasapogenol B biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_9209 GO:1901092 positive regulation of protein tetramerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901092 up regulation of protein tetramer assembly|activation of protein tetramer assembly|positive regulation of protein tetramer assembly|up regulation of protein tetramerization|activation of protein tetramerization|upregulation of protein tetramer formation|up-regulation of protein tetramer biosynthesis|up-regulation of protein tetramer biosynthetic process|up-regulation of protein tetramer assembly|up-regulation of protein tetramer formation|up-regulation of protein tetramerization|activation of protein tetramer formation|upregulation of protein tetramer biosynthesis|upregulation of protein tetramer biosynthetic process|upregulation of protein tetramer assembly|upregulation of protein tetramerization|positive regulation of protein tetramer formation|up regulation of protein tetramer biosynthesis|up regulation of protein tetramer biosynthetic process|up regulation of protein tetramer formation|positive regulation of protein tetramer biosynthesis|activation of protein tetramer biosynthesis|activation of protein tetramer biosynthetic process|positive regulation of protein tetramer biosynthetic process Any process that activates or increases the frequency, rate or extent of protein tetramerization. CHEBI:36261 taurodeoxycholate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36261 CHEBI:36262 molybdenum oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36262 GO:1901090 regulation of protein tetramerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901090 regulation of protein tetramer formation|regulation of protein tetramer biosynthesis|regulation of protein tetramer biosynthetic process|regulation of protein tetramer assembly Any process that modulates the frequency, rate or extent of protein tetramerization. CHEBI:36260 monohydroxy-5beta-cholanic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36260 CHEBI:36265 transition element oxoacid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36265 CHEBI:36263 hydrogenmolybdate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36263 CHEBI:36264 molybdate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36264 CHEBI:75800 (2'->5')-dinucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75800 CHEBI:36280 oct-2-enedioate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36280 CHEBI:131528 aurachin B biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131528 GO:1901099 negative regulation of signal transduction in absence of ligand biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901099 down regulation of basal signaling|down-regulation of non-classical signal transduction|negative regulation of non-classical signal transduction|downregulation of basal signaling|down-regulation of signal transduction in absence of ligand|down-regulation of basal signaling|down regulation of signal transduction in absence of agonist|downregulation of signal transduction in absence of agonist|down regulation of non-classical signal transduction|downregulation of signal transduction in absence of ligand|downregulation of non-classical signal transduction|down regulation of signal transduction in absence of ligand|down-regulation of signal transduction in absence of agonist|negative regulation of signal transduction in absence of agonist|inhibition of signal transduction in absence of ligand Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction in absence of ligand. CHEBI:36278 cholanic acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36278 CHEBI:36279 oct-2-enedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36279 GO:0012510 trans-Golgi network transport vesicle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0012510 trans-Golgi network constitutive secretory pathway transport vesicle membrane|TGN transport vesicle membrane The lipid bilayer surrounding a vesicle transporting substances between the trans-Golgi network and other parts of the cell. CHEBI:131522 dTDP-4-(methylamino)-2,3,4,6-tetradeoxy-alpha-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131522 GO:0012511 monolayer-surrounded lipid storage body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0012511 Wikipedia:Oil_body oleosome|oilbody|oil body|spherosome A subcellular organelle of plant cells surrounded by 'half-unit' or a monolayer membrane instead of the more usual bilayer. The storage body has a droplet of triglyceride surrounded by a monolayer of phospholipids, interacting with the triglycerides and the hydrophilic head groups facing the cytosol, and containing major protein components called oleosins. CHEBI:36272 tungstic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36272 CHEBI:36270 tungsten oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36270 CHEBI:36271 hydrogentungstate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36271 CHEBI:9211 soyasaponin I biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_9211 CHEBI:36274 glycochenodeoxycholic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36274 CHEBI:36275 HETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36275 CHEBI:75819 8-oxo-ETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75819 CHEBI:36248 5beta-cholanic acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36248 CHEBI:36246 5alpha-cholanic acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36246 CHEBI:36249 bile acid conjugate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36249 CHEBI:36240 3alpha,7alpha,12beta-trihydroxy-5beta-cholanic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36240 CHEBI:36243 propanoate ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36243 CHEBI:36244 dicarboxylic acid monoester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36244 CHEBI:36241 3,4-dihydroxybenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36241 CHEBI:36242 3-(4-hydroxyphenyl)pyruvate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36242 CHEBI:75822 (8S,9S)-epoxy-(10R)-hydroxyicosa-(5Z,11Z,14Z)-trienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75822 CHEBI:51877 bisindole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51877 CHEBI:51879 bisindole alkaloid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51879 CHEBI:75824 2,3-dioleoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75824 CHEBI:75825 (7R)-hydroxy-(5S,6S)-epoxy-(8Z,11Z,14Z)-icosatrienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75825 CHEBI:36258 but-2-enoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36258 CHEBI:36259 taurolithocholic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36259 CHEBI:36257 taurocholate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36257 CHEBI:36255 bile acid glycine conjugate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36255 CHEBI:36252 glycochenodeoxycholate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36252 GO:0061440 kidney vasculature development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061440 The process whose specific outcome is the progression of the vasculature of the kidney over time, from its formation to the mature structure. GO:0061441 renal artery morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061441 The process in which the anatomical structure of a renal artery is generated and organized. Renal arteries supply the kidneys with blood. GO:0061442 cardiac muscle cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061442 The process involved in cardiac muscle cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment. GO:0036475 neuron death in response to oxidative stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036475 oxidative stress-induced neuron death|neuronal cell death in response to oxidative stress Any biological process that results in permanent cessation of all vital functions of a neuron upon exposure to an oxidative stress stimulus. GO:0036476 neuron death in response to hydrogen peroxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036476 neuron death in response to H2O2|neuronal cell death in response to hydrogen peroxide|hydrogen peroxide-induced neuron death Any biological process that results in permanent cessation of all vital functions of a neuron upon exposure to hydrogen peroxide (H2O2). GO:0061443 endocardial cushion cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061443 The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cushion cell. GO:0061444 endocardial cushion cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061444 The process whose specific outcome is the progression of an endocardial cushion cell over time, from its formation to the mature state. GO:0036477 somatodendritic compartment biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036477 The region of a neuron that includes the cell body (cell soma) and dendrite(s), but excludes the axon. GO:0036478 L-dopa decarboxylase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036478 DDC activator activity Interacts with and increases L-dopa decarboxylase activity. GO:0061445 endocardial cushion cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061445 The commitment of a cell to an endocardial cushion cell fate and its capacity to differentiate into an endocardial cushion cell. GO:0036479 peroxidase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036479 Interacts with, and stops, prevents or reduces the activity of a peroxidase. GO:0061446 endocardial cushion cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061446 The process involved in endocardial cushion cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment. GO:0061447 endocardial cushion cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061447 The process involved in the specification of endocardial cushion cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. GO:0061448 connective tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061448 The progression of a connective tissue over time, from its formation to the mature structure. GO:0061449 olfactory bulb tufted cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061449 The process whose specific outcome is the progression of an olfactory bulb tufted cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. GO:0036470 tyrosine 3-monooxygenase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036470 tyrosine hydroxylase activator activity|TH activator activity Interacts with and increases tyrosine 3-monooxygenase (tyrosine hydroxylase) activity. GO:0036471 cellular response to glyoxal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036471 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glyoxal stimulus. GO:0036472 suppression by virus of host protein-protein interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036472 suppression by virus of host protein:protein interaction|suppression by virus of host protein interaction|suppression by virus of host protein:protein binding|suppression by virus of host protein binding Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of interaction between host proteins. GO:0036473 cell death in response to oxidative stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036473 Any biological process that results in permanent cessation of all vital functions of a cell upon exposure to an oxidative stress stimulus. GO:0036474 cell death in response to hydrogen peroxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036474 cell death in response to H2O2|hydrogen peroxide-mediated cell death Any biological process that results in permanent cessation of all vital functions of a cell upon exposure to hydrogen peroxide (H2O2). CHEBI:85195 9,10-epoxyoctadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85195 CHEBI:85197 9,10-dihydroxystearate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85197 CHEBI:85198 N-arachidonoylsphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85198 CHEBI:85199 N-icosenoylsphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85199 GO:0061430 bone trabecula morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061430 The process of shaping a trabecula in bone. A trabecula is a tissue element in the form of a small beam, strut or rod. GO:0061431 cellular response to methionine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061431 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methionine stimulus. GO:0036464 cytoplasmic ribonucleoprotein granule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036464 Staufen granule A ribonucleoprotein granule located in the cytoplasm. GO:0036465 synaptic vesicle recycling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036465 kiss-and-stay synaptic vesicle recycling|kiss-and-run synaptic vesicle recycling The trafficking of synaptic vesicles from the pre-synaptic membrane so the vesicle can dock and prime for another round of exocytosis and neurotransmitter release. Recycling occurs after synaptic vesicle exocytosis, and is necessary to replenish presynaptic vesicle pools, sustain transmitter release and preserve the structural integrity of the presynaptic membrane. Recycling can occur following transient fusion with the presynaptic membrane (kiss and run), or via endocytosis of presynaptic membrane. GO:0061432 obsolete regulation of transcription from RNA polymerase II promoter in response to methionine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061432 OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a methionine stimulus. GO:0036466 synaptic vesicle recycling via endosome biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0036466 recycling endosome localization within postsynapse Synaptic vesicle recycling where vesicles endocytosed via clathrin-coated pits re-acidify and refill with neurotransmitters after passing through an endosomal intermediate. GO:0061433 cellular response to caloric restriction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061433 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a of caloric restriction, insufficient food energy intake. GO:0061434 obsolete regulation of replicative cell aging by regulation of transcription from RNA polymerase II promoter in response to caloric restriction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061434 OBSOLETE. Any process that modulates the frequency, rate or extent of replicative cell aging through a mechanism that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a caloric restriction stimulus. GO:0036467 5-hydroxy-L-tryptophan decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036467 RHEA:18533 5-hydroxytryptophan decarboxylase activity Catalysis of the reaction: 5-hydroxy-L-tryptophan + H+ = CO2 + serotonin. GO:0061435 positive regulation of transcription from a mobile element promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061435 Any process that activates or increases the frequency, rate or extent of transcription from a mobile element promoter. GO:0036468 L-dopa decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036468 RHEA:12272 DDC activity|4-dihydroxyl-L-phenylalanine decarboxylase activity|DOPA decarboxylase activity Catalysis of the reaction: L-dopa + H+ = CO2 + dopamine. GO:0061436 establishment of skin barrier biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061436 skin barrier development|epithelial barrier development|establishment of epithelial barrier Establishment of the epithelial barrier, the functional barrier in the skin that limits its permeability. GO:0036469 L-tryptophan decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036469 RHEA:30339|EC:4.1.1.105 L-tryptophan decarboxylase activity Catalysis of the reaction: L-tryptophan + H+ = CO2 + tryptamine. GO:0061437 renal system vasculature development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061437 The process whose specific outcome is the progression of vasculature of the renal system over time, from its formation to the mature structure. GO:0061438 renal system vasculature morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061438 The process in which the renal system vasculature is generated and organized. Morphogenesis pertains to the creation of form. GO:0061439 kidney vasculature morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061439 The process in which the kidney vasculature is generated and organized. Morphogenesis pertains to the creation of form. GO:0036460 cellular response to cell envelope stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036460 envelope stress response Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stress acting at the cell envelope. GO:0036461 BLOC-2 complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036461 Interacting selectively and non-covalently with a BLOC-2 complex, a protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. GO:0036462 TRAIL-activated apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036462 TRAIL-activated extrinsic apoptotic signaling pathway|TRAIL-induced apoptotic signaling pathway|tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway An extrinsic apoptotic signaling pathway initiated by the binding of the ligand TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) to a death receptor on the cell surface. GO:0036463 TRAIL receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036463 tumor necrosis factor-related apoptosis-inducing ligand receptor Combining with the ligand TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) and transmitting the signal from one side of the plasma membrane to the other to initiate apoptotic cell death. GO:2000005 negative regulation of metanephric S-shaped body morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000005 Any process that stops, prevents, or reduces the frequency, rate or extent of metanephric S-shaped body morphogenesis. GO:2000006 regulation of metanephric comma-shaped body morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000006 Any process that modulates the frequency, rate or extent of metanephric comma-shaped body morphogenesis. GO:2000007 negative regulation of metanephric comma-shaped body morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000007 Any process that stops, prevents, or reduces the frequency, rate or extent of metanephric comma-shaped body morphogenesis. GO:2000008 regulation of protein localization to cell surface biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000008 regulation of protein localisation at cell surface|regulation of protein localization at cell surface Any process that modulates the frequency, rate or extent of protein localization to the cell surface. GO:2000009 negative regulation of protein localization to cell surface biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000009 negative regulation of protein localisation at cell surface|negative regulation of protein localization at cell surface Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to the cell surface. GO:0061460 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0061460 GO:0061461 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0061461 GO:0061462 protein localization to lysosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061462 A process in which a protein is transported to, or maintained in, a location within a lysosome. GO:0061463 O-acetyl-ADP-ribose deacetylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061463 Catalysis of the reaction O-acetyl-ADP-ribose + H2O = ADP-ribose + acetate. GO:0036453 transitive RNA interference biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036453 transitive RNAi An RNA interference where the silencing signal spreads along the target mRNA in a 5' or 3' direction, outside of the initial target sequence. GO:0061464 obsolete plasma membrane part of cell-substrate junction biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061464 OBSOLETE. The part of the plasma membrane that contributes to the structure of a cell-substrate junction. GO:0061465 obsolete plasma membrane part of hemidesmosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061465 OBSOLETE. The part of the plasma membrane that contributes to the structure of a hemidesmosome. GO:0036454 growth factor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036454 A protein complex that has growth factor activity. GO:0036455 iron-sulfur transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036455 Reactome:R-HSA-2564828 Fe-S transferase activity Catalysis of the transfer of a iron-sulfur cluster from one compound (donor) to another (acceptor). GO:0061466 obsolete plasma membrane part of cell junction biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061466 OBSOLETE. The part of the plasma membrane that contributes to the structure of a cell junction. GO:0036456 L-methionine-(S)-S-oxide reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036456 RHEA:19995 Catalysis of the reaction: L-methionine (S)-S-oxide + thioredoxin -> L-methionine + thioredoxin disulfide + H2O. GO:0061467 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0061467 GO:0061468 karyomere biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061468 A membrane-bound intermediate cleavage-stage structure of individual or groups of chromosomes that coalesces and fuses with other karyomeres to form a nucleus during interphase. Karyomere formation occurs in blastomeres undergoing rapid cell division. GO:0036457 keratohyalin granule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036457 A cytoplasmic, non-membrane bound granule of, at least, keratinocyte. Associated to keratin intermediate filaments and partially crosslinked to the cell envelope. GO:2000001 regulation of DNA damage checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000001 regulation of DNA damage response, signal transduction resulting in cell cycle arrest Any process that modulates the frequency, rate or extent of a DNA damage checkpoint. GO:0036458 hepatocyte growth factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036458 HGF binding Interacting selectively and non-covalently with a hepatocyte growth factor. GO:2000002 negative regulation of DNA damage checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000002 negative regulation of DNA damage response, signal transduction resulting in cell cycle arrest Any process that stops, prevents, or reduces the frequency, rate or extent of a DNA damage checkpoint. GO:0061469 regulation of type B pancreatic cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061469 Any process that modulates the frequency, rate or extent of type B pancreatic cell proliferation. GO:2000003 positive regulation of DNA damage checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000003 positive regulation of DNA damage response, signal transduction resulting in cell cycle arrest Any process that activates or increases the frequency, rate or extent of a DNA damage checkpoint. GO:0036459 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0036459 GO:2000004 regulation of metanephric S-shaped body morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000004 Any process that modulates the frequency, rate or extent of metanephric S-shaped body morphogenesis. GO:0036450 polyuridylation-dependent decapping of nuclear-transcribed mRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036450 uridylation-dependent decapping of nuclear-transcribed mRNA Cleavage of the 5'-cap of a nuclear-transcribed mRNA that has been modified by the enzymatic addition of a sequence of uridylyl residues (polyuridylation) at the 3' end. GO:0036451 cap mRNA methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036451 Methylation of the 2'-O-ribose of the first or second transcribed nucleotide of a 5'-capped mRNA. GO:0036452 ESCRT complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036452 Wikipedia:ESCRT endosomal sorting complex required for transport An endosomal sorting complex involved in membrane fission processes related to sorting of multivesicular bodies (MVB) in the endocytic pathway, cytokinesis and viral budding among other processes. GO:2000016 negative regulation of determination of dorsal identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000016 negative regulation of determination of adaxial identity Any process that stops, prevents, or reduces the frequency, rate or extent of determination of dorsal identity. GO:2000017 positive regulation of determination of dorsal identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000017 positive regulation of determination of adaxial identity Any process that activates or increases the frequency, rate or extent of determination of dorsal identity. GO:2000018 regulation of male gonad development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000018 regulation of testicular development|regulation of testis development Any process that modulates the frequency, rate or extent of male gonad development. GO:2000019 negative regulation of male gonad development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000019 negative regulation of testis development|negative regulation of testicular development Any process that stops, prevents, or reduces the frequency, rate or extent of male gonad development. GO:0061450 trophoblast cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061450 Trophoblast cell migration that is accomplished by extension and retraction of a pseudopodium. Trophoblast cells line the outside of the blastocyst. GO:0061451 retrotrapezoid nucleus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061451 The progression of the retrotrapezoid nucleus (RTN) over time from it's initial formation to its mature state. The retrotrapezoid nucleus is a group of neurons in the rostral medulla, which are responsible regulating respiration. GO:0061452 retrotrapezoid nucleus neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061452 The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the retrotrapezoid nucleus. GO:0036442 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0036442 GO:0061453 interstitial cell of Cajal differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061453 ICC differentiation The process in which a relatively unspecialized cell acquires specialized features of an interstitial cell of Cajal. An interstitial cell of Cajal is an intestinal neuroepithelial cell that serves as a pacemaker to trigger gut contraction. GO:0061454 release of sequestered calcium ion into cytosol by Golgi biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061454 Golgi calcium ion export The directed movement of calcium ions (Ca2+) out of the Golgi apparatus into the cytosol. GO:0036443 dermatan 6-sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036443 KEGG_REACTION:R07288 Catalysis of the reaction: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan 6'-sulfate. GO:2000010 positive regulation of protein localization to cell surface biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000010 positive regulation of protein localisation at cell surface|positive regulation of protein localization at cell surface Any process that activates or increases the frequency, rate or extent of protein localization to the cell surface. GO:0061455 integral component of muscle cell projection membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061455 integral to muscle cell projection membrane The component of the muscle cell projection membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0036444 calcium import into the mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036444 mitochondrial calcium ion import|mitochondrial calcium uptake|calcium ion transmembrane import into mitochondrion|calcium ion import into mitochondrion A process in which a calcium ion (Ca2+) is transported from the cytosol, into the mitochondrial matrix. GO:0061456 mesenchymal stem cell migration involved in uteric bud morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061456 The orderly movement of a mesenchymal stem cell from one site to another contributing to the shaping of the ureteric bud. A mesenchymal stem cell, or MSC, is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells. GO:2000011 regulation of adaxial/abaxial pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000011 regulation of adaxial/abaxial pattern specification Any process that modulates the frequency, rate or extent of adaxial/abaxial pattern formation. GO:0036445 neuronal stem cell division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036445 NSC division The self-renewing division of a neuronal stem cell. GO:0061457 mesonephric cell migration involved in male gonad development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061457 The orderly movement of a cell from the mesonephros to the male gonad, contributing to its development. GO:0036446 myofibroblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036446 myofibroblast cell differentiation The process in which an undifferentiated cell acquires the features of a myofibroblast cell. GO:2000012 regulation of auxin polar transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000012 Any process that modulates the frequency, rate or extent of auxin polar transport. GO:2000013 regulation of arginine biosynthetic process via ornithine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000013 regulation of arginine formation via ornithine|regulation of arginine anabolism via ornithine|regulation of arginine synthesis via ornithine Any process that modulates the frequency, rate or extent of arginine biosynthetic process via ornithine. GO:0061458 reproductive system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061458 The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction. GO:0036447 cellular response to sugar-phosphate stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036447 cellular response to presence of non-metabolizable sugars Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the accumulation of sugar-phosphate. GO:0061459 L-arginine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061459 ATP-dependent L-arginine transmembrane transporter activity|arginine porter activity|ATPase-coupled L-arginine transmembrane transporter activity|L-arginine-importing ATPase activity|arginine-importing ATPase activity Enables the stereospecific transfer of L-arginine, 2-amino-5-guanidinopentanoic acid, across a biological membrane. GO:0036448 cellular response to glucose-phosphate stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036448 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the accumulation of glucose-phosphate. GO:2000014 regulation of endosperm development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000014 Any process that modulates the frequency, rate or extent of endosperm development. GO:2000015 regulation of determination of dorsal identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000015 regulation of determination of adaxial identity Any process that modulates the frequency, rate or extent of determination of dorsal identity. GO:0036449 microtubule minus-end biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036449 microtubule minus end The end of a microtubule that does not preferentially grow (polymerize). GO:0036440 citrate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036440 RHEA:16845|KEGG_REACTION:R00351 Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA. GO:0036441 2-dehydropantolactone reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036441 KEGG_REACTION:R03155|RHEA:18981 Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+. GO:1901008 (S)-scoulerine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901008 (S)-scoulerine breakdown|(S)-scoulerine catabolism|(S)-scoulerine degradation The chemical reactions and pathways resulting in the breakdown of (S)-scoulerine. GO:1901009 (S)-scoulerine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901009 (S)-scoulerine anabolism|(S)-scoulerine biosynthesis|(S)-scoulerine synthesis|(S)-scoulerine formation The chemical reactions and pathways resulting in the formation of (S)-scoulerine. GO:1901006 ubiquinone-6 biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901006 ubiquinone-6 biosynthesis|ubiquinone-6 anabolism|ubiquinone-6 synthesis|ubiquinone-6 formation The chemical reactions and pathways resulting in the formation of ubiquinone-6. GO:0036439 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0036439 GO:1901007 (S)-scoulerine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901007 (S)-scoulerine metabolism The chemical reactions and pathways involving (S)-scoulerine. GO:1901004 ubiquinone-6 metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901004 coenzyme Q6 metabolism|ubiquinone-6 metabolism|coenzyme Q6 metabolic process The chemical reactions and pathways involving ubiquinone-6. Ubiquinone-6 is a ubiquinone compound having a (2E,6E,10E,14E,18E)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-yl substituent at position 2. GO:0061480 response to asparaginase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061480 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an asparaginase stimulus. GO:1901005 ubiquinone-6 catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901005 ubiquinone-6 breakdown|ubiquinone-6 catabolism|ubiquinone-6 degradation The chemical reactions and pathways resulting in the breakdown of ubiquinone-6. GO:0061481 response to TNF agonist biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061481 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a TNF agonist stimulus. GO:1901002 positive regulation of response to salt stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901002 positive regulation of response to ionic osmotic stress|upregulation of response to salt stress|upregulation of salinity response|up regulation of response to ionic osmotic stress|up regulation of response to salt stress|activation of response to salt stress|up regulation of salinity response|upregulation of response to ionic osmotic stress|positive regulation of salinity response|activation of salinity response|up-regulation of response to ionic osmotic stress|up-regulation of response to salt stress|up-regulation of salinity response|activation of response to ionic osmotic stress Any process that activates or increases the frequency, rate or extent of response to salt stress. GO:0061482 response to irinotecan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061482 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an irinotecan stimulus. GO:1901003 negative regulation of fermentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901003 down-regulation of fermentation|downregulation of fermentation|down regulation of fermentation|inhibition of fermentation Any process that stops, prevents or reduces the frequency, rate or extent of fermentation. GO:0061483 sulfinylpropanyl adenylate synthase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061483 SPA synthase Catalysis of the reaction: cysteine sulfanate + GTP + IMP = sulfinylpropanyl adenylate + GDP + 3 H(+) + phosphate. GO:1901000 regulation of response to salt stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901000 regulation of response to ionic osmotic stress|regulation of salinity response Any process that modulates the frequency, rate or extent of response to salt stress. GO:0061484 hematopoietic stem cell homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061484 Any biological process involved in the maintenance of the steady-state number of hematopoietic stem cells within a population of cells. GO:1901001 negative regulation of response to salt stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901001 inhibition of salinity response|down regulation of response to salt stress|downregulation of response to ionic osmotic stress|down regulation of salinity response|downregulation of response to salt stress|down regulation of response to ionic osmotic stress|downregulation of salinity response|down-regulation of response to salt stress|inhibition of response to ionic osmotic stress|negative regulation of salinity response|down-regulation of salinity response|inhibition of response to salt stress|negative regulation of response to ionic osmotic stress|down-regulation of response to ionic osmotic stress Any process that stops, prevents or reduces the frequency, rate or extent of response to salt stress. GO:0061485 memory T cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061485 The expansion of a memory T cell population by cell division. GO:0036431 dCMP kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036431 RHEA:25094|MetaCyc:RXN-11831|MetaCyc:RXN-7913|KEGG_REACTION:R01665 ATP:dCMP phosphotransferase activity Catalysis of the reaction: ATP + dCMP = ADP + dCDP. GO:0061486 high-affinity fructose transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061486 high affinity fructose transmembrane transporter activity Enables the transfer of fructose from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. CHEBI:131593 3-deoxy-D-glycero-beta-D-galacto-nonulosonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131593 GO:0036432 all-trans undecaprenol kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036432 RHEA:23752 Catalysis of the reaction: ATP + undecaprenol + all-trans-undecaprenyl phosphate + ADP + H+. GO:1901010 (S)-reticuline metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901010 (S)-reticuline metabolism The chemical reactions and pathways involving (S)-reticuline. GO:0061487 obsolete DNA replication initiation from late origin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061487 late replication origin firing OBSOLETE. The process in which DNA-dependent DNA replication is started at a late origin of replication. A late origin of replication refers to an origin that is activated late in S phase. GO:0036433 di-trans, poly-cis-undecaprenol kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036433 RHEA:28122|MetaCyc:UNDECAPRENOL-KINASE-RXN|KEGG_REACTION:R05626 ditrans,polycis-undecaprenol kinase activity Catalysis of the reaction: di-trans, octa-cis-undecaprenol + ATP = di-trans,octa-cis-undecaprenyl phosphate + ADP + H+. GO:0061488 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0061488 GO:0036434 nitronate monooxygenase (FMN-linked) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036434 KEGG_REACTION:R00025|RHEA:26458 Catalysis of the reaction: ethylnitronate + FMNH(2) + O(2) = acetaldehyde + FMN + H(2)O + H(+) + nitrite. GO:0061489 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0061489 CHEBI:131596 CMP-3-deoxy-D-glycero-beta-D-galacto-nonulosonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131596 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036435 Reactome:R-HSA-5683077 Interacting selectively and non-covalently with a protein upon poly-ubiquitination formed by linkages between lysine residues at position 48 in the target protein. GO:0036436 Isw1a complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036436 An Isw1 complex that binds DNA and has nucleosome-stimulated ATPase activity. In S. cerevisiae, contains an Isw1p ATPase subunit in complex with Ioc3p. GO:0036437 Isw1b complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036437 An Isw1 complex that binds DNA and has nucleosome-stimulated ATPase activity. In S. cerevisiae, contains an Isw1p ATPase subunit in complex with Ioc2p and Ioc4p. GO:0036438 maintenance of lens transparency biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036438 preservation of lens transparency|maintenance of ocular lens transparency A homeostatic process in which the lens is maintained in a highly refractive, transparent state to allow for optimal focusing of light on the retina. CHEBI:131591 C18-steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131591 GO:0036430 CMP kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036430 MetaCyc:RXN-11832|KEGG_REACTION:R00512|RHEA:11600 Catalysis of the reaction: ATP + CMP = ADP + CDP. GO:1901019 regulation of calcium ion transmembrane transporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901019 Any process that modulates the frequency, rate or extent of calcium ion transmembrane transporter activity. GO:1901017 negative regulation of potassium ion transmembrane transporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901017 downregulation of potassium transporter activity|downregulation of potassium ion transmembrane transporter activity|down regulation of potassium transporter activity|down regulation of potassium ion transmembrane transporter activity|inhibition of potassium ion transmembrane transporter activity|inhibition of potassium transporter activity|negative regulation of potassium transporter activity|down-regulation of potassium transporter activity|down-regulation of potassium ion transmembrane transporter activity Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transporter activity. GO:0036428 adenosylcobinamide kinase (GTP-specific) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036428 MetaCyc:RXN-14063|KEGG_REACTION:R06558|RHEA:15765 Catalysis of the reaction: adenosylcobinamide + GTP = adenosylcobinamide phosphate + GDP + H+. GO:1901018 positive regulation of potassium ion transmembrane transporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901018 positive regulation of potassium transporter activity|up regulation of potassium transporter activity|up regulation of potassium ion transmembrane transporter activity|upregulation of potassium transporter activity|upregulation of potassium ion transmembrane transporter activity|up-regulation of potassium transporter activity|up-regulation of potassium ion transmembrane transporter activity|activation of potassium ion transmembrane transporter activity|activation of potassium transporter activity Any process that activates or increases the frequency, rate or extent of potassium ion transmembrane transporter activity. GO:0036429 adenosylcobinamide kinase (ATP-specific) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036429 MetaCyc:COBINAMIDEKIN-RXN|RHEA:15769|KEGG_REACTION:R05221 Catalysis of the reaction: adenosylcobinamide + ATP = adenosylcobinamide phosphate + ADP + H+. GO:1901015 3alpha(S)-strictosidine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901015 3alpha(S)-strictosidine anabolism|3alpha(S)-strictosidine synthesis|3alpha(S)-strictosidine formation|3alpha(S)-strictosidine biosynthesis The chemical reactions and pathways resulting in the formation of 3alpha(S)-strictosidine. GO:1901016 regulation of potassium ion transmembrane transporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901016 regulation of potassium transporter activity Any process that modulates the frequency, rate or extent of potassium ion transmembrane transporter activity. GO:0061470 T follicular helper cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061470 T-helper follicular cell differentiation The process in which a relatively unspecialized T cell acquires specialized features of a mature T follicular helper cell. GO:0061471 karyomere assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061471 The process where the nuclear membrane engulfs condensed chromosomes to form karyomeres during M phase of the mitotic cell cycle. GO:1901013 3alpha(S)-strictosidine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901013 3alpha(S)-strictosidine metabolism The chemical reactions and pathways involving 3alpha(S)-strictosidine. GO:0061472 karyomere membrane fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061472 Process whereby karyomere membranes fuse during interphase to form a single lobed nucleus. GO:1901014 3alpha(S)-strictosidine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901014 3alpha(S)-strictosidine catabolism|3alpha(S)-strictosidine degradation|3alpha(S)-strictosidine breakdown The chemical reactions and pathways resulting in the breakdown of 3alpha(S)-strictosidine. GO:1901011 (S)-reticuline catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901011 (S)-reticuline catabolism|(S)-reticuline degradation|(S)-reticuline breakdown The chemical reactions and pathways resulting in the breakdown of (S)-reticuline. GO:0061473 murein tripeptide carboxypeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061473 Catalysis of the reaction L-Ala-gamma-D-Glu-meso-Dap (murein tripeptide) + H2O = L-Ala-gamma-D-Glu + meso-diaminopimelate. GO:1901012 (S)-reticuline biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901012 (S)-reticuline anabolism|(S)-reticuline synthesis|(S)-reticuline biosynthesis|(S)-reticuline formation The chemical reactions and pathways resulting in the formation of (S)-reticuline. GO:0061474 phagolysosome membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061474 The lipid bilayer surrounding a phagolysosome. GO:1901020 negative regulation of calcium ion transmembrane transporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901020 down-regulation of calcium ion transmembrane transporter activity|downregulation of calcium ion transmembrane transporter activity|down regulation of calcium ion transmembrane transporter activity|inhibition of calcium ion transmembrane transporter activity Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transporter activity. GO:0036420 extrinsic component of mycolate outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036420 extrinsic to MOM|extrinsic to mycomembrane|extrinsic to mycolate outer membrane The component of mycolate outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:0061475 cytosolic valyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061475 The process of coupling valine to valyl-tRNA in the cytosol, catalyzed by valyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. NCBITaxon:554915 Amoebozoa organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_554915 GO:0061476 response to anticoagulant biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061476 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anticoagulant stimulus. GO:1901021 positive regulation of calcium ion transmembrane transporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901021 up regulation of calcium ion transmembrane transporter activity|upregulation of calcium ion transmembrane transporter activity|up-regulation of calcium ion transmembrane transporter activity|activation of calcium ion transmembrane transporter activity Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transporter activity. GO:0036421 extrinsic component of external side of mycolate outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036421 extrinsic to external side of MOM|extrinsic to external side of mycolate outer membrane|extrinsic to external side of mycomembrane The component of mycolate membrane consisting of gene products and protein complexes that are loosely bound to its external surface, but not integrated into the hydrophobic region. GO:0036422 heptaprenyl diphosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036422 MetaCyc:TRANS-HEXAPRENYLTRANSTRANSFERASE-RXN|EC:2.5.1.30|RHEA:27794 heptaprenyl pyrophosphate synthetase activity|all-trans-heptaprenyl-diphosphate synthase activity|heptaprenyl pyrophosphate synthase activity|HepPP synthase activity Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + 4 isopentenyl diphosphate = 4 diphosphate + all-trans-heptaprenyl diphosphate. GO:0061477 response to aromatase inhibitor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061477 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aromatase inhibitor stimulus. GO:0061478 response to platelet aggregation inhibitor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061478 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet aggregation inhibitor stimulus. GO:0036423 hexaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036423 MetaCyc:TRANS-PENTAPRENYLTRANSFERASE-RXN|RHEA:27559|EC:2.5.1.83|KEGG_REACTION:R09245 hexaprenyl diphosphate synthase activity|hexaprenyl pyrophosphate synthetase activity Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + 3 isopentenyl diphosphate = 3 diphosphate + all-trans-hexaprenyl diphosphate. GO:0061479 response to reverse transcriptase inhibitor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061479 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reverse transcriptase inhibitor stimulus. GO:0036424 L-phosphoserine phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036424 RHEA:21208|MetaCyc:RXN0-5114|KEGG_REACTION:R00582 Catalysis of the reaction: O-phospho-L-serine + H2O <=> L-serine + phosphate. GO:0036425 D-phosphoserine phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036425 KEGG_REACTION:R02853|RHEA:24873 Catalysis of the reaction: O-phospho-D-serine + H2O <=> L-serine + phosphate. GO:0036426 ditrans, polycis-undecaprenyl-phosphate mannosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036426 MetaCyc:2.4.1.54-RXN|KEGG_REACTION:R07257 Catalysis of the reaction: ditrans,octacis-undecaprenyl phosphate + GDP-alpha-D-mannose = D-mannosyl undecaprenyl phosphate+ GDP. GO:0036427 all-trans-undecaprenyl-phosphate mannosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036427 RHEA:28118 Catalysis of the reaction: all-trans-undecaprenyl phosphate + GDP-alpha-D-mannose = D-mannosyl undecaprenyl phosphate + GDP. OBO:GOCHE_27026 substance with toxin role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_27026 OBO:GOCHE_27027 substance with micronutrient role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_27027 GO:0036417 tRNA destabilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036417 Any process that decreases the stability of a tRNA molecule, making it more vulnerable to degradative processes. GO:1901028 regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901028 regulation of MOMP|regulation of mitochondrial outer membrane permeabilization Any process that modulates the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway. CHEBI:131579 pApA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131579 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901029 down regulation of mitochondrial outer membrane permeabilization|downregulation of mitochondrial outer membrane permeabilization|negative regulation of mitochondrial outer membrane permeabilization|down-regulation of MOMP|negative regulation of MOMP|down-regulation of mitochondrial outer membrane permeabilization|inhibition of mitochondrial outer membrane permeabilization|downregulation of MOMP|down regulation of MOMP|inhibition of MOMP Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway. GO:0036418 intrinsic component of mycolate outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036418 intrinsic to mycomembrane|intrinsic to MOM|intrinsic to mycolate outer membrane The component of the mycolate outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:1901026 ripoptosome assembly involved in necroptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901026 ripoptosome assembly involved in necroptosis The aggregation, arrangement and bonding together of ripoptosome components leading to a necroptotic process. GO:0036419 integral component of mycolate outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036419 integral to mycolate outer membrane|integral to mycomembrane|integral to MOM The component of the mycolate outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:1901027 dextrin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901027 dextrin degradation|dextrin breakdown|dextrin catabolism The chemical reactions and pathways resulting in the breakdown of dextrin. GO:1901024 4-hydroxyphenylacetate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901024 4-hydroxyphenylacetate synthesis|4-hydroxyphenylacetate formation|4-hydroxyphenylacetate biosynthesis|4-hydroxyphenylacetate anabolism The chemical reactions and pathways resulting in the formation of 4-hydroxyphenylacetate. GO:1901025 ripoptosome assembly involved in extrinsic apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901025 The aggregation, arrangement and bonding together of ripoptosome components leading to apoptosis via the extrinsic apoptotic signaling pathway. GO:1901022 4-hydroxyphenylacetate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901022 4-hydroxyphenylacetate metabolism The chemical reactions and pathways involving 4-hydroxyphenylacetate. GO:1901023 4-hydroxyphenylacetate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901023 4-hydroxyphenylacetate degradation|4-hydroxyphenylacetate catabolism|4-hydroxyphenylacetate breakdown The chemical reactions and pathways resulting in the breakdown of 4-hydroxyphenylacetate. GO:1901031 regulation of response to reactive oxygen species biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901031 regulation of response to ROI|regulation of response to reactive oxidative species|regulation of response to AOS|regulation of response to reactive oxygen intermediate|regulation of response to ROS|regulation of response to active oxygen species Any process that modulates the frequency, rate or extent of response to reactive oxygen species. GO:0036410 Mst2 histone acetyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036410 Mst2 H3K14 acetyltransferase complex|Mst2 complex|Mst2 histone H3K14 acetyltransferase complex A protein complex that can catalyze the acetylation of lysine at position 14 in histone H3, and contains Mst2 as the catalytic subunit. In fission yeast, contains at least Mst2, Nto1, Ptf2, Ptf1 and Eaf6. GO:1901032 negative regulation of response to reactive oxygen species biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901032 down-regulation of response to reactive oxygen intermediate|negative regulation of response to reactive oxygen intermediate|down regulation of response to ROI|inhibition of response to AOS|down-regulation of response to ROS|negative regulation of response to active oxygen species|down-regulation of response to active oxygen species|negative regulation of response to ROS|downregulation of response to reactive oxidative species|downregulation of response to ROI|down regulation of response to AOS|downregulation of response to reactive oxygen intermediate|down regulation of response to reactive oxidative species|down regulation of response to reactive oxygen species|downregulation of response to AOS|down regulation of response to reactive oxygen intermediate|downregulation of response to reactive oxygen species|down-regulation of response to ROI|negative regulation of response to ROI|inhibition of response to reactive oxidative species|inhibition of response to ROS|inhibition of response to active oxygen species|inhibition of response to reactive oxygen intermediate|negative regulation of response to AOS|down-regulation of response to AOS|down regulation of response to active oxygen species|down-regulation of response to reactive oxygen species|down regulation of response to ROS|inhibition of response to ROI|downregulation of response to ROS|downregulation of response to active oxygen species|negative regulation of response to reactive oxidative species|down-regulation of response to reactive oxidative species|inhibition of response to reactive oxygen species Any process that stops, prevents or reduces the frequency, rate or extent of response to reactive oxygen species. CHEBI:131572 3'-L-prolyl-AMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131572 GO:0036411 H-NS-Cnu complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036411 A trimeric protein complex containing a H-NS homodimer and a Cnu monomer. In bacteria, this complex negatively regulates transcription of a range of genes. GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901030 upregulation of MOMP|upregulation of mitochondrial outer membrane permeabilization|up-regulation of MOMP|activation of MOMP|positive regulation of mitochondrial outer membrane permeabilization|up regulation of mitochondrial outer membrane permeabilization|activation of mitochondrial outer membrane permeabilization|positive regulation of MOMP|up regulation of MOMP|up-regulation of mitochondrial outer membrane permeabilization Any process that activates or increases the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway. GO:0036412 acetyl-CoA:oxalate CoA-transferase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036412 RHEA:37883 Catalysis of the reaction: acetyl-CoA + oxalate = acetate + oxalyl-CoA. GO:0036413 histone H3-R26 citrullination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036413 histone H3 arginine 26 citrullination The hydrolysis of peptidyl-arginine to form peptidyl-citrulline at position 26 in histone H3. GO:0036414 histone citrullination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036414 histone deimination The hydrolysis of peptidyl-arginine to form peptidyl-citrulline on a histone protein. GO:0036415 regulation of tRNA stability biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036415 Any process that modulates the propensity of transfer RNA (tRNA) molecules to degradation. Includes processes that both stabilize and destabilize tRNAs. GO:0036416 tRNA stabilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036416 Prevention of degradation of tRNA molecules. GO:0036406 anchored component of periplasmic side of cell outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036406 anchored to periplasmic side of cell outer membrane|anchored to internal side of cell outer membrane The component of the cell outer membrane consisting of gene products and protein complexes that are tethered to the periplasmic side of membrane by only a covalently attached anchor, embedded in the periplasmic side of the membrane only. GO:1901039 regulation of peptide antigen transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901039 Any process that modulates the frequency, rate or extent of peptide antigen transport. GO:0061490 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0061490 GO:0036407 mycolate outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036407 mycolate outer membrane|mycobacterial outer membrane|MOM|mycomembrane A mycolic acid-rich cell outer membrane containing a lipid bilayer and long-chain mycolic acids (hydroxylated branched-chain fatty acids) that are covalently linked to the cell wall peptidoglycan via an arabinogalactan network. Found in mycobacteria and related genera (e.g. corynebacteria). GO:1901037 obsolete regulation of transcription from RNA polymerase II promoter during M/G1 transition of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901037 regulation of transcription from Pol II promoter during M/G1 transition of mitotic cell cycle|regulation of transcription from RNA polymerase II promoter involved in M/G1 transition of mitotic cell cycle|regulation of gene-specific transcription from RNA polymerase II promoter during M/G1 transition of mitotic cell cycle|regulation of transcription from RNA polymerase II promoter during M/G1 transition of mitotic cell cycle|global transcription regulation from Pol II promoter during M/G1 transition of mitotic cell cycle|regulation of transcription during M/G1 transition of mitotic cell cycle|regulation of global transcription from Pol II promoter during M/G1 transition of mitotic cell cycle OBSOLETE. Any process that regulates transcription such that the target genes are transcribed during the M/G1 transition of the mitotic cell cycle. GO:0036408 histone acetyltransferase activity (H3-K14 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036408 histone lysine N-acetyltransferase activity (H3-K14 specific) Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 14) = CoA + histone H3 N6-acetyl-L-lysine (position 14). GO:0061491 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0061491 GO:0061492 asymmetric protein localization to old or new spindle pole body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061492 Any process in which a protein is transported to, or maintained to either the old or new spindle pole body resulting in its being distributed asymmetrically. GO:0036409 histone H3-K14 acetyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036409 H3-K14 histone acetyltransferase complex|histone acetyltransferase complex (H3-K14 specific)|histone H3K14 acetyltransferase complex|histone H3 Lys 14 (H3K14) acetyltransferase complex A protein complex that can catalyze the acetylation of lysine at position 14 in histone H3. GO:1901038 cyanidin 3-O-glucoside metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901038 cyanidin 3-O-beta-D-glucoside metabolic process|cyanidin 3-O-beta-D-glucoside metabolism The chemical reactions and pathways involving cyanidin 3-O-beta-D-glucoside. GO:0061493 central plaque of mitotic spindle pole body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061493 One of three laminate structures that form the mitotic spindle pole body; the inner plaque is on the nuclear face of the spindle pole body. GO:1901035 negative regulation of L-glutamine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901035 negative regulation of L-glutamine import|down-regulation of L-glutamine uptake|negative regulation of L-glutamine uptake|downregulation of L-glutamine import|down-regulation of L-glutamine import|downregulation of L-glutamine uptake|down regulation of L-glutamine import|inhibition of L-glutamine import|down regulation of L-glutamine uptake|inhibition of L-glutamine uptake Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamine import into a cell. GO:0061494 gamma-tubulin large complex, mitotic spindle pole body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061494 A complex of gamma tubulin and associated proteins thought to be formed by multimerization of gamma-tubulin small complexes located in the mitotic spindle pole body. GO:1901036 positive regulation of L-glutamine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901036 up-regulation of L-glutamine uptake|positive regulation of L-glutamine import|activation of L-glutamine uptake|up regulation of L-glutamine import|positive regulation of L-glutamine uptake|up regulation of L-glutamine uptake|upregulation of L-glutamine import|upregulation of L-glutamine uptake|up-regulation of L-glutamine import|activation of L-glutamine import Any process that activates or increases the frequency, rate or extent of L-glutamine import into cell. GO:1901033 positive regulation of response to reactive oxygen species biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901033 up-regulation of response to reactive oxygen species|up regulation of response to active oxygen species|upregulation of response to ROI|up regulation of response to ROS|activation of response to reactive oxygen intermediate|positive regulation of response to ROS|positive regulation of response to active oxygen species|positive regulation of response to reactive oxidative species|up regulation of response to reactive oxidative species|positive regulation of response to reactive oxygen intermediate|activation of response to active oxygen species|activation of response to ROS|upregulation of response to AOS|up regulation of response to reactive oxygen intermediate|upregulation of response to reactive oxygen species|up regulation of response to ROI|positive regulation of response to ROI|up-regulation of response to active oxygen species|up-regulation of response to ROS|upregulation of response to reactive oxidative species|activation of response to ROI|up regulation of response to AOS|upregulation of response to reactive oxygen intermediate|positive regulation of response to AOS|up regulation of response to reactive oxygen species|activation of response to reactive oxygen species|upregulation of response to active oxygen species|upregulation of response to ROS|up-regulation of response to reactive oxidative species|up-regulation of response to ROI|activation of response to AOS|up-regulation of response to reactive oxygen intermediate|activation of response to reactive oxidative species|up-regulation of response to AOS Any process that activates or increases the frequency, rate or extent of response to reactive oxygen species. GO:0061495 gamma-tubulin small complex, mitotic spindle pole body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061495 A complex composed of two gamma-tubulin molecules and conserved non-tubulin proteins located in the mitotic spindle pole body and isolated by fractionation from cells. The complex, approximately 6S-9S, is analogous to the small complex in animal cells but contains fewer subunits, and is not thought to multimerize into larger functional units, like complexes in those organisms. An example of this structure is found in Saccharomyces cerevisiae. GO:0061496 half bridge of mitotic spindle pole body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061496 Structure adjacent to the plaques of the mitotic spindle pole body. GO:1901034 regulation of L-glutamine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901034 regulation of L-glutamine import|regulation of L-glutamine uptake Any process that modulates the frequency, rate or extent of L-glutamine import into cell. GO:0061497 inner plaque of mitotic spindle pole body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061497 One of three laminate structures that form the mitotic spindle pole body; the inner plaque is in the nucleus. GO:1901042 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1901042 CHEBI:131582 8,12-diethyl-3-vinylbacteriochlorophyllide d biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131582 GO:1901043 obsolete protein polyubiquitination involved in cellular response to misfolded protein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901043 polyubiquitin of cellular response to misfolded protein|protein polyubiquitinylation of cellular response to misfolded protein|protein polyubiquitination involved in cellular response to misfolded protein|protein polyubiquitination of cellular response to misfolded protein|protein polyubiquitylation of cellular response to misfolded protein OBSOLETE. Any protein polyubiquitination that is involved in cellular response to misfolded protein. GO:0061498 intermediate layer of mitotic spindle pole body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061498 Structure between the central and outer plaques of the mitotic spindle pole body. GO:1901040 negative regulation of peptide antigen transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901040 inhibition of peptide antigen transport|down regulation of peptide antigen transport|downregulation of peptide antigen transport|down-regulation of peptide antigen transport Any process that stops, prevents or reduces the frequency, rate or extent of peptide antigen transport. GO:0061499 outer plaque of mitotic spindle pole body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061499 One of three laminate structures that form the mitotic spindle pole body; the outer plaque is in the cytoplasm. GO:0036400 short neuropeptide F receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036400 sNPF receptor activity Combining with a short neuropeptide F and transmitting the signal within the cell to initiate a change in cell activity. Short neuropeptide F is an arthropod peptide of less than 28 residues (as small as 8-10 residues in some species) with a C-terminal RFamide or LRFamide. GO:0036401 pyrokinin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036401 PK receptor activity Combining with a pyrokinin and transmitting the signal within the cell to induce a change in cell activity. Pyrokinins are a group of insect neuropeptides that share the common C-terminal pentapeptide sequence Phe-X-Pro-Arg-Leu-NH2 (X = S, T, K, A, or G). They play a central role in diverse physiological processes including stimulation of gut motility, production and release of sex pheromones, diapause, and pupariation. GO:1901041 positive regulation of peptide antigen transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901041 up-regulation of peptide antigen transport|upregulation of peptide antigen transport|up regulation of peptide antigen transport|activation of peptide antigen transport Any process that activates or increases the frequency, rate or extent of peptide antigen transport. GO:0036402 proteasome-activating ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036402 proteasomal ATPase activity|ATPase involved in positive regulation of proteasomal protein catabolic process|proteasome channel gating activity|proteasome channel opening activity Catalysis of the reaction: ATP + H2O = ADP + phosphate, which promotes unfolding of protein substrates, and channel opening of the core proteasome. GO:0036403 arachidonate 8(S)-lipoxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036403 KEGG_REACTION:R07053|EC:1.13.11.-|RHEA:38675 8-lipoxygenase (S-type)|8(S)-lipoxygenase activity Catalysis of the reaction: arachidonate + O(2) = (5Z,8S,9E,11Z,14Z)-8-hydroperoxyicosa-5,9,11,14-tetraenoate. CHEBI:131587 12-ethyl-8-propyl-3-vinylbacteriochlorophyllide d biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131587 GO:0036404 conversion of ds siRNA to ss siRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036404 conversion of double-stranded small interfering RNA to single-stranded small interfering RNA The process in which double-stranded small interfering RNA (ds siRNA) molecules are converted to single-stranded small interfering RNA (ss siRNA). CHEBI:131588 12-ethyl-8-isobutyl-3-vinylbacteriochlorophyllide d biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131588 GO:0036405 anchored component of cell outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036405 anchored to cell outer membrane The component of the cell outer membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. CHEBI:131589 3-deoxy-D-glycero-beta-D-galacto-nonulosonic acid 9-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131589 CHEBI:26822 sulfide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26822 CHEBI:26825 sulfobenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26825 CHEBI:75799 3-beta-D-glucosyl-1,2-diacyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75799 CHEBI:26820 sulfates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26820 GO:0120219 subapical part of cell biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120219 subapical region of cell The region of a polarized cell that is just below the apical region. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue so the subapical region is further from the exposed surface and closer to the basal lamina. CHEBI:61151 poly-ADP-D-ribose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61151 CHEBI:61150 2,3-dihydro-3-oxoanthranilate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61150 GO:0120215 positive regulation of histidine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120215 up-regulation of histidine synthesis|up-regulation of histidine formation|up-regulation of histidine biosynthetic process|up-regulation of histidine biosynthesis|activation of histidine biosynthetic process|activation of histidine biosynthesis|upregulation of histidine anabolism|upregulation of histidine synthesis|upregulation of histidine formation|positive regulation of histidine biosynthesis|up regulation of histidine anabolism|activation of histidine anabolism|up regulation of histidine biosynthesis|up regulation of histidine biosynthetic process|positive regulation of histidine anabolism|up regulation of histidine synthesis|activation of histidine synthesis|positive regulation of histidine synthesis|up regulation of histidine formation|activation of histidine formation|positive regulation of histidine formation|upregulation of histidine biosynthetic process|upregulation of histidine biosynthesis|up-regulation of histidine anabolism Any process that activates or increases the frequency, rate or extent of histidine biosynthetic process. GO:0120216 matrilin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120216 matrilin-4 complex|matrilin family complex|matrilin-3 complex|matrilin-2 complex|matrilin-1 complex A cartilage extracellular matrix complex that mediates interactions between major components of the extracellular matrix such as collagens and proteoglycans and contributes to their fibrillar network. Exists as an obligate homotrimer. GO:0120217 DNA gyrase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120217 topoisomerase II complex A bacterial type IIA topoisomerase that is unique in its function of introducing negative supercoils into DNA at the expense of ATP hydrolysis and is also capable of relaxing positive supercoils, an activity shared with topoisomerase IV. Typically, it is composed of two copies each of an A subunit (GyrA) and a B subunit (GyrB). GO:0120218 host interaction involved in quorum sensing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120218 A quorum sensing process that is modulated by some interaction with a host cell or organism. GO:2000063 positive regulation of ureter smooth muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000063 Any process that activates or increases the frequency, rate or extent of ureter smooth muscle cell differentiation. GO:0120211 proacrosomal vesicle fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120211 Fusion of the membrane of proacrosomal vesicle with the membrane of another proacrosomal vesicle to form the acrosome. CHEBI:61159 conjugated linoleic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61159 GO:0120212 sperm head-tail coupling apparatus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120212 head-tail coupling apparatus|HTCA A centrosome-based structure consisting of two cylindrical microtubule-based centrioles and associated components which anchors the flagellum to the sperm head. GO:2000064 regulation of cortisol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000064 regulation of cortisol biosynthesis|regulation of cortisol synthesis|regulation of cortisol anabolism|regulation of cortisol formation Any process that modulates the frequency, rate or extent of cortisol biosynthetic process. GO:2000065 negative regulation of cortisol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000065 negative regulation of cortisol anabolism|negative regulation of cortisol synthesis|negative regulation of cortisol formation|negative regulation of cortisol biosynthesis Any process that stops, prevents, or reduces the frequency, rate or extent of cortisol biosynthetic process. GO:0120213 regulation of histidine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120213 regulation of histidine anabolism|regulation of histidine synthesis|regulation of histidine formation|regulation of histidine biosynthesis Any process that modulates the frequency, rate or extent of histidine biosynthetic process. GO:2000066 positive regulation of cortisol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000066 positive regulation of cortisol synthesis|positive regulation of cortisol anabolism|positive regulation of cortisol formation|positive regulation of cortisol biosynthesis Any process that activates or increases the frequency, rate or extent of cortisol biosynthetic process. GO:0120214 negative regulation of histidine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120214 inhibition of histidine formation|down regulation of histidine anabolism|down-regulation of histidine biosynthetic process|down-regulation of histidine biosynthesis|negative regulation of histidine biosynthesis|down regulation of histidine synthesis|downregulation of histidine anabolism|down regulation of histidine formation|downregulation of histidine synthesis|downregulation of histidine formation|downregulation of histidine biosynthetic process|downregulation of histidine biosynthesis|negative regulation of histidine anabolism|down-regulation of histidine anabolism|down regulation of histidine biosynthetic process|down regulation of histidine biosynthesis|negative regulation of histidine synthesis|down-regulation of histidine synthesis|inhibition of histidine biosynthetic process|inhibition of histidine biosynthesis|negative regulation of histidine formation|down-regulation of histidine formation|inhibition of histidine anabolism|inhibition of histidine synthesis Any process that stops, prevents or reduces the frequency, rate or extent of histidine biosynthetic process. CHEBI:61158 3''-hydroxy-geranylhydroquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61158 GO:2000067 regulation of root morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000067 Any process that modulates the frequency, rate or extent of root morphogenesis. GO:2000068 regulation of defense response to insect biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000068 regulation of physiological defense response to insect Any process that modulates the frequency, rate or extent of defense response to insect. GO:2000069 regulation of post-embryonic root development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000069 Any process that modulates the frequency, rate or extent of post-embryonic root development. GO:0120210 rod telodendria biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120210 Rod telodendria are projections that originate from the rod pedicle and form gap junctions with other photoreceptors within the outer plexiform layer of the retina. CHEBI:75792 1,2-diacyl-sn-glycero-3-phospho-1'-(3'-O-L-lysyl)-sn-glycerol(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75792 CHEBI:75793 1,2-diacyl-sn-glycero-3-phospho-1'-(3'-O-L-alanyl)-sn-glycerol zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75793 CHEBI:26826 dihydroxybenzenesulfonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26826 GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000060 positive regulation of protein ubiquitination during ubiquitin-dependent protein catabolism|positive regulation of protein degradation tagging activity|positive regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolic process|positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|positive regulation of protein ubiquitylation during ubiquitin-dependent protein catabolism|positive regulation of protein ubiquitylation during ubiquitin-dependent protein catabolic process|positive regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolism|positive regulation of protein ubiquitination during ubiquitin-dependent protein degradation|positive regulation of protein ubiquitination during ubiquitin-dependent protein breakdown Any process that activates or increases the frequency, rate or extent of ubiquitin-dependent protein catabolic process. GO:2000061 regulation of ureter smooth muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000061 Any process that modulates the frequency, rate or extent of ureter smooth muscle cell differentiation. GO:2000062 negative regulation of ureter smooth muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000062 Any process that stops, prevents, or reduces the frequency, rate or extent of ureter smooth muscle cell differentiation. CHEBI:26829 sulfoglycolipid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26829 CHEBI:26833 sulfur atom biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_26833 CHEBI:26834 sulfur-containing amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26834 CHEBI:26835 sulfur molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26835 CHEBI:26836 sulfuric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26836 CHEBI:26830 sulfonium compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26830 CHEBI:26831 N,N''-sulfonyldiurea biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26831 CHEBI:61162 poly(3-hydroxycarboxylic acid) macromolecule biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61162 CHEBI:61163 D-alanyl-(R)-lactic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61163 CHEBI:61160 conjugated linolenic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61160 CHEBI:85110 (3E,5Z)-dienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85110 GO:0120226 succinyl-CoA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120226 succinyl-coenzyme A binding Interacting selectively and non-covalently with succinyl-CoA, an omega-carboxyacyl-CoA having succinoyl as the S-acyl component. CHEBI:85111 6-saturated-trans,trans-2,4-dienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85111 CHEBI:61166 D-alanyl-(R)-lactic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61166 GO:0120227 acyl-CoA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120227 acyl binding|acyl-coenzyme A binding Interacting selectively and non-covalently with an acyl-CoA, a thioester that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of any carboxylic acid. GO:0120228 outer dynein arm docking complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120228 ODA docking complex|ODA-DC A complex which stabilizes the binding of and correctly positions the outer dynein arm complex along an A-tubule of the flagellar axoneme outer doublet microtubules. GO:0120229 protein localization to motile cilium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120229 protein localization to nonmotile primary cilium A process in which a protein is transported to, or maintained in, a location within a motile cilium. CHEBI:61165 D-alanyl ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61165 GO:0120222 regulation of blastocyst development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120222 Any process that modulates the frequency, rate or extent of blastocyst development. GO:2000074 regulation of type B pancreatic cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000074 regulation of pancreatic beta cell development|regulation of pancreatic B cell development Any process that modulates the frequency, rate or extent of pancreatic B cell development. GO:2000075 negative regulation of cytokinesis, site selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000075 negative regulation of site selection involved in cell cycle cytokinesis Any process that stops, prevents, or reduces the frequency, rate or extent of site selection that occurs as part of cytokinesis. GO:0120223 larynx morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120223 laryngeal morphogenesis The process in which the larynx is generated and organized. The larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration. GO:0120224 larynx development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120224 The biological process whose specific outcome is the progression of a larynx from an initial condition to its mature state. This process begins with the formation of the larynx and ends with the mature structure. A larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration. GO:2000076 positive regulation of cytokinesis, site selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000076 positive regulation of site selection involved in cell cycle cytokinesis Any process that activates or increases the frequency, rate or extent of site selection that occurs as part of cytokinesis. GO:2000077 negative regulation of type B pancreatic cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000077 negative regulation of pancreatic beta cell development|negative regulation of pancreatic B cell development Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic B cell development. GO:0120225 coenzyme A binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120225 CoA binding Interacting selectively and non-covalently with coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester. GO:2000078 positive regulation of type B pancreatic cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000078 positive regulation of pancreatic B cell development|positive regulation of pancreatic beta cell development Any process that activates or increases the frequency, rate or extent of pancreatic B cell development. GO:2000079 regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000079 regulation of canonical Wnt receptor signalling pathway involved in controlling pancreatic B cell proliferation|regulation of canonical Wnt receptor signaling pathway involved in controlling pancreatic B cell proliferation|regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation|regulation of canonical Wnt receptor signaling pathway involved in pancreatic beta cell proliferation|regulation of canonical Wnt receptor signalling pathway involved in controlling type B pancreatic cell proliferation|regulation of canonical Wnt-activated signaling pathway involved in controlling type B pancreatic cell proliferation Any process that modulates the frequency, rate or extent of canonical Wnt signaling pathway modulating the rate or frequency of pancreatic B cell proliferation. GO:0120220 basal body patch biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120220 centriolar patch The region in the apical portion of multiciliated epithelial cells where the ciliary basal bodies cluster. GO:0120221 maintenance of ciliary planar beating movement pattern biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120221 Any process involved in maintaining the planar beating pattern of ciliary movement pattern. Connection between the outer doublets and the central pair via the radial spokes constrains ciliary movement to the planar beating pattern. Cilia that lack this connection, such as those in the embryonic node or Kupfer's vesicle, display radial movement. GO:2000070 regulation of response to water deprivation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000070 regulation of response to thirst|regulation of drought tolerance|regulation of response to drought|regulation of response to dehydration Any process that modulates the frequency, rate or extent of response to water deprivation. GO:2000071 regulation of defense response by callose deposition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000071 regulation of callose deposition during defense response|regulation of callose localization during defense response Any process that modulates the frequency, rate or extent of defense response by callose deposition. GO:2000072 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2000072 GO:2000073 regulation of cytokinesis, site selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000073 regulation of site selection involved in cell cycle cytokinesis Any process that modulates the frequency, rate or extent of site selection that occurs as part of cytokinesis. CHEBI:85140 (9Z)-12-(phosphonooxy)octadecenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85140 CHEBI:85141 (9Z)-12-(phosphonooxy)octadecenoate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85141 CHEBI:85142 methyl nogalonate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85142 GO:0120237 terminal acetylenic compound biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120237 terminal alkyne substituted compound anabolic process|terminal alkyne substituted compound anabolism|terminal alkyne substituted compound synthesis|terminal alkyne substituted compound biosynthesis|terminal alkyne substituted compound biosynthetic process The chemical reactions and pathways resulting in the formation of a terminal acetylenic compound, a compound which contains a terminal alkyne moiety in which a carbon of the carbon-carbon triple bond (aka C#C) moiety is attached to a hydrogen atom. GO:0120238 sperm glycocalyx biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120238 The carbohydrate rich layer at the outermost periphery of a sperm cell. GO:0120239 vascular endothelial glycocalyx biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120239 endothelial glycocalyx The carbohydrate-rich layer lining the vascular endothelium connected to the endothelium through a variety of molecules, mainly proteoglycans and glycoproteins. These form a network in which soluble molecules, either plasma- or endothelium-derived, are incorporated. CHEBI:85148 3-hydroxytetradecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85148 GO:2000085 negative regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000085 negative regulation of mesonephric mesenchyme to epithelial transition Any process that stops, prevents, or reduces the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis. GO:0120233 prenyl-FMNH2 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120233 prenylated FMNH2 binding Interacting selectively and non-covalently with prenyl-FMNH2, a flavin mononucleotide obtained by prenylation of the N-10 position of FMNH2 followed by cyclisation. An essential cofactor for the decarboxylase enzymes UbiD and Fdc1. GO:0120234 stereocilium coat biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120234 stereocilium glycocalyx|auditory hair cell glycocalyx A glycocalyx on the the endolymphatic surface of a cochlear hair cell that coats the external surface of each stereocilium and maintains a small distance between adjacent stereocilia in the bundle. GO:2000086 positive regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000086 positive regulation of mesonephric mesenchyme to epithelial transition Any process that activates or increases the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis. GO:2000087 regulation of mesonephric glomerulus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000087 Any process that modulates the frequency, rate or extent of mesonephric glomerulus development. GO:0120235 regulation of posttranslational protein targeting to membrane, translocation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120235 regulation of posttranslational endoplasmic reticulum membrane protein translocation|regulation of SRP-independent endoplasmic reticulum protein-membrane targeting, translocation|regulation of N-terminal signal peptide-independent translocation into the ER Any process that modulates the frequency, rate or extent of posttranslational protein translocation through the ER membrane. GO:2000088 negative regulation of mesonephric glomerulus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000088 Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric glomerulus development. GO:0120236 negative regulation of posttranslational protein targeting to membrane, translocation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120236 negative regulation of N-terminal signal peptide-independent translocation into the ER|negative regulation of posttranslational endoplasmic reticulum membrane protein translocation|negative regulation of SRP-independent endoplasmic reticulum protein-membrane targeting, translocation Any process that stops, prevents or reduces the frequency, rate or extent of posttranslational protein translocation through the ER membrane. GO:2000089 positive regulation of mesonephric glomerulus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000089 Any process that activates or increases the frequency, rate or extent of mesonephric glomerulus development. GO:0120230 recombinase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120230 Binds to and increases the activity of a recombinase. GO:0120231 DNA recombinase auxiliary factor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120231 DNA recombinase activator complex|DNA recombinase accessory factor complex A protein complex that binds to a recombinase and incrseases its activity. GO:0120232 prenyl-FMNH2 biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120232 prenyl-FMNH2 anabolism|prenylated FMNH2 anabolism|prenyl-FMNH2 synthesis|prenylated FMNH2 synthesis|prenyl-FMNH2 formation|prenylated FMNH2 formation|prenylated FMNH2 biosynthetic process|prenylated FMNH2 biosynthesis|prenyl-FMNH2 biosynthesis The chemical reactions and pathways resulting in prenyl-FMNH2, an essential cofactor for the decarboxylase enzymes UbiD and Fdc1. GO:2000080 negative regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000080 negative regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation|negative regulation of canonical Wnt receptor signaling pathway involved in controlling pancreatic B cell proliferation|negative regulation of canonical Wnt receptor signaling pathway involved in pancreatic beta cell proliferation|negative regulation of canonical Wnt receptor signalling pathway involved in controlling pancreatic B cell proliferation|negative regulation of canonical Wnt receptor signalling pathway involved in controlling type B pancreatic cell proliferation|negative regulation of canonical Wnt-activated signaling pathway involved in controlling type B pancreatic cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of canonical Wnt signaling pathway modulating the rate or frequency of pancreatic B cell proliferation. GO:2000081 positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000081 positive regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation|positive regulation of canonical Wnt receptor signaling pathway involved in pancreatic beta cell proliferation|positive regulation of canonical Wnt receptor signaling pathway involved in controlling pancreatic B cell proliferation|positive regulation of canonical Wnt receptor signalling pathway involved in controlling pancreatic B cell proliferation|positive regulation of canonical Wnt receptor signalling pathway involved in controlling type B pancreatic cell proliferation|positive regulation of canonical Wnt-activated signaling pathway involved in controlling type B pancreatic cell proliferation Any process that activates or increases the frequency, rate or extent of canonical Wnt signaling pathway modulating the rate or frequency of pancreatic B cell proliferation. GO:2000082 regulation of L-ascorbic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000082 regulation of ascorbate biosynthesis|regulation of ascorbate biosynthetic process|regulation of L-ascorbic acid anabolism|regulation of L-ascorbic acid synthesis|regulation of L-ascorbic acid formation|regulation of L-ascorbic acid biosynthesis|regulation of vitamin C biosynthetic process|regulation of vitamin C biosynthesis Any process that modulates the frequency, rate or extent of L-ascorbic acid biosynthetic process. CHEBI:26806 succinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26806 GO:2000083 negative regulation of L-ascorbic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000083 negative regulation of L-ascorbic acid formation|negative regulation of ascorbate biosynthesis|negative regulation of ascorbate biosynthetic process|negative regulation of L-ascorbic acid biosynthesis|negative regulation of vitamin C biosynthesis|negative regulation of vitamin C biosynthetic process|negative regulation of L-ascorbic acid anabolism|negative regulation of L-ascorbic acid synthesis Any process that stops, prevents, or reduces the frequency, rate or extent of L-ascorbic acid biosynthetic process. GO:2000084 regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000084 regulation of mesonephric mesenchyme to epithelial transition Any process that modulates the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis. PR:000013743 Ras GTPase-activating protein 1 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000013743 RASA|p120GAP|RASA1|RasGAP|GTPase-activating protein|ras p21 protein activator|GAP A protein that is a translation product of the human RASA1 gene or a 1:1 ortholog thereof. CHEBI:85130 7,8-dihydroxanthopterin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85130 CHEBI:61185 L-pipecolic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61185 GO:0120248 acetylenic compound catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120248 alkyne substituted compound degradation|alkyne substituted compound breakdown|alkyne substituted compound catabolic process|alkyne substituted compound catabolism The chemical reactions and pathways resulting in the breakdown of an acetylenic compound, any compound which contains a carbon-carbon triple bond (aka C#C). CHEBI:85133 12-(phosphonooxy)octadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85133 CHEBI:85134 12-(phosphonooxy)octadecanoate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85134 GO:0120249 lateral wall of outer hair cell biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120249 outer hair cell lateral wall|lateral wall of OHC|OHC lateral wall The lateral wall of an outer hair cell (OHC) is a unique trilaminate composite consisting of the plasma membrane, an underlying cytoskeletal network containing an actin-spectrin cortical lattice, and an adjacent system of circumferential lamellar organelles known as the subsurface cisternae. CHEBI:61186 7,8-dihydromonapterin 3-triphosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61186 CHEBI:85136 (9E)-12-(phosphonooxy)octadecenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85136 GO:0120244 terminal acetylenic compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120244 terminal alkyne substituted compound metabolism|terminal alkyne substituted compound metabolic process The chemical reactions and pathways involving a terminal acetylenic compound, involving a terminal acetylenic compound, a compound which contains a terminal alkyne moiety in which which a carbon of the carbon-carbon triple bond (aka C#C) moiety is attached to a hydrogen atom. GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000096 positive regulation of non-canonical Wnt signaling pathway|positive regulation of Wnt receptor signalling pathway, planar cell polarity pathway|positive regulation of Wnt-PCP signaling pathway|positive regulation of PCP pathway|positive regulation of Wnt-activated signaling pathway, planar cell polarity pathway|positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway|positive regulation of Wnt-JNK signaling pathway Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway, planar cell polarity pathway. CHEBI:85137 (9E)-12-(phosphonooxy)octadecenoate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85137 GO:2000097 regulation of smooth muscle cell-matrix adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000097 Any process that modulates the frequency, rate or extent of smooth muscle cell-matrix adhesion. GO:0120245 terminal acetylenic compound catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120245 terminal alkyne substituted compound degradation|terminal alkyne substituted compound breakdown|terminal alkyne substituted compound catabolic process|terminal alkyne substituted compound catabolism The chemical reactions and pathways resulting in the breakdown of a terminal acetylenic compound, a compound which contains a terminal alkyne moiety in which a carbon of the carbon-carbon triple bond (aka C#C) moiety is attached to a hydrogen atom. GO:0120246 acetylenic compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120246 alkyne substituted compound metabolism|alkyne substituted compound metabolic process The chemical reactions and pathways involving an acetylenic compound, any compound which contains a carbon-carbon triple bond (aka C#C). GO:2000098 negative regulation of smooth muscle cell-matrix adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000098 Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell-matrix adhesion. CHEBI:85139 beta-amino acid ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85139 GO:0120247 acetylenic compound biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120247 alkyne substituted compound biosynthetic process|alkyne substituted compound biosynthesis|alkyne substituted compound anabolism|alkyne substituted compound synthesis|alkyne substituted compound anabolic process The chemical reactions and pathways resulting in the formation of an acetylenic compound, any compound which contains a carbon-carbon triple bond (aka C#C). GO:2000099 regulation of establishment or maintenance of bipolar cell polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000099 Any process that modulates the frequency, rate or extent of establishment or maintenance of bipolar cell polarity. GO:0120240 platelet glycocalyx biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120240 The carbohydrate rich layer at the outermost periphery of a platelet. GO:0120241 2-iminobutanoate/2-iminopropanoate deaminase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120241 EC:3.5.99.10 enamine/imine deaminase|2-iminobutanoate deaminase|2-iminopropanoate deaminase|imine intermediate deaminase activity Catalyzes the hydrolytic deamination of imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases, such as EC 4.3.1.19 and EC 4.3.1.17. GO:0120242 2-iminobutanoate deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120242 KEGG_REACTION:R11098|RHEA:39975|MetaCyc:RXN-15123 2-iminobutanoate/2-iminopropanoate deaminase Catalysis of the reaction: 2-iminobutanoate + H2O = 2-oxobutanoate + NH4(+). GO:0120243 2-iminopropanoate deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120243 RHEA:40671|KEGG_REACTION:R11099|MetaCyc:RXN-15127 2-iminobutanoate/2-iminopropanoate deaminase Catalysis of the reaction: 2-iminopropanoate + H2O = NH4(+) + pyruvate. CHEBI:26819 sulfuric ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_26819 GO:2000090 regulation of mesonephric glomerular mesangial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000090 Any process that modulates the frequency, rate or extent of mesonephric glomerular mesangial cell proliferation. GO:2000091 negative regulation of mesonephric glomerular mesangial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000091 Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric glomerular mesangial cell proliferation. GO:2000092 positive regulation of mesonephric glomerular mesangial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000092 Any process that activates or increases the frequency, rate or extent of mesonephric glomerular mesangial cell proliferation. GO:2000093 regulation of mesonephric nephron tubule epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000093 Any process that modulates the frequency, rate or extent of mesonephric nephron tubule epithelial cell differentiation. CHEBI:26816 carbohydrate phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26816 GO:2000094 negative regulation of mesonephric nephron tubule epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000094 Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric nephron tubule epithelial cell differentiation. GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000095 regulation of PCP pathway|regulation of Wnt-activated signaling pathway, planar cell polarity pathway|regulation of Wnt-JNK signaling pathway|regulation of non-canonical Wnt signaling pathway|regulation of Wnt receptor signalling pathway, planar cell polarity pathway|regulation of Wnt receptor signaling pathway, planar cell polarity pathway|regulation of Wnt-PCP signaling pathway Any process that modulates the frequency, rate or extent of Wnt signaling pathway, planar cell polarity pathway. CHEBI:61191 7,8-dihydromonapterin 3-triphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61191 CHEBI:61190 beta-D-GalpNAc-(1->4)-D-GlcpNAc biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61190 GO:2000027 regulation of animal organ morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000027 regulation of histogenesis and organogenesis Any process that modulates the frequency, rate or extent of animal organ morphogenesis. GO:2000028 regulation of photoperiodism, flowering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000028 regulation of response to day length, flowering|regulation of photoperiodic control of inflorescence development|regulation of response to night length, flowering|regulation of photoperiodic control of flowering time|regulation of response to photoperiod, flowering Any process that modulates the frequency, rate or extent of photoperiodism, flowering. GO:2000029 regulation of proanthocyanidin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000029 regulation of proanthocyanidin biosynthesis|regulation of proanthocyanidin anabolism|regulation of proanthocyanidin synthesis|regulation of proanthocyanidin formation Any process that modulates the frequency, rate or extent of proanthocyanidin biosynthetic process. CHEBI:61194 2'-deoxyinosine 5'-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61194 CHEBI:85165 prostaglandin G2 2-glyceryl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85165 CHEBI:85166 prostaglandin H2 2-glyceryl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85166 CHEBI:61197 phlobaphene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61197 GO:2000020 positive regulation of male gonad development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000020 positive regulation of testis development|positive regulation of testicular development Any process that activates or increases the frequency, rate or extent of male gonad development. GO:0061400 positive regulation of transcription from RNA polymerase II promoter in response to calcium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061400 Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to a calcium ion stimulus. GO:2000021 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2000021 GO:0061401 obsolete positive regulation of transcription from RNA polymerase II promoter in response to a hypotonic environment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061401 OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of detection of, or exposure to, a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. GO:2000022 regulation of jasmonic acid mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000022 regulation of jasmonic acid mediated signalling pathway Any process that modulates the frequency, rate or extent of jasmonic acid mediated signaling pathway. GO:0061402 positive regulation of transcription from RNA polymerase II promoter in response to acidic pH biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061402 positive regulation of transcription from RNA polymerase II promoter in response to acidity Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a pH stimulus with pH < 7. GO:2000023 regulation of lateral root development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000023 Any process that modulates the frequency, rate or extent of lateral root development. GO:0061403 positive regulation of transcription from RNA polymerase II promoter in response to nitrosative stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061403 Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions. GO:2000024 regulation of leaf development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000024 Any process that modulates the frequency, rate or extent of leaf development. GO:2000025 regulation of leaf formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000025 Any process that modulates the frequency, rate or extent of leaf formation. GO:0061404 obsolete positive regulation of transcription from RNA polymerase II promoter in response to increased salt biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061404 OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. GO:0061405 positive regulation of transcription from RNA polymerase II promoter in response to hydrostatic pressure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061405 Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it. GO:2000026 regulation of multicellular organismal development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000026 Any process that modulates the frequency, rate or extent of multicellular organismal development. GO:0061406 positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061406 Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of glucose. GO:0061407 positive regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061407 Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hydrogen peroxide (H2O2) stimulus. GO:0061408 positive regulation of transcription from RNA polymerase II promoter in response to heat stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061408 Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism. GO:0061409 positive regulation of transcription from RNA polymerase II promoter in response to freezing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061409 Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a freezing stimulus, temperatures below 0 degrees Celsius. CHEBI:85150 (9Z)-12-hydroxyoctadec-9-enoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85150 GO:2000038 regulation of stomatal complex development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000038 Any process that modulates the frequency, rate or extent of stomatal complex development. GO:2000039 regulation of trichome morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000039 regulation of trichome cell morphogenesis during differentiation Any process that modulates the frequency, rate or extent of trichome morphogenesis. CHEBI:85152 (9E)-12-hydroxyoctadec-9-enoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85152 GO:2000030 regulation of response to red or far red light biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000030 Any process that modulates the frequency, rate or extent of response to red or far red light. GO:2000031 regulation of salicylic acid mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000031 regulation of salicylic acid mediated signalling pathway Any process that modulates the frequency, rate or extent of salicylic acid mediated signaling pathway. GO:2000032 regulation of secondary shoot formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000032 regulation of auxiliary shoot formation|regulation of axillary shoot system formation|regulation of axillary shoot formation|regulation of shoot branching Any process that modulates the frequency, rate or extent of secondary shoot formation. GO:2000033 regulation of seed dormancy process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000033 regulation of seed dormancy Any process that modulates the frequency, rate or extent of seed dormancy process. GO:2000034 regulation of seed maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000034 Any process that modulates the frequency, rate or extent of seed maturation. GO:2000035 regulation of stem cell division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000035 regulation of stem cell renewal Any process that modulates the frequency, rate or extent of stem cell division. GO:2000036 regulation of stem cell population maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000036 regulation of maintenance of pluripotency Any process that modulates the frequency, rate or extent of stem cell population maintenance. GO:2000037 regulation of stomatal complex patterning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000037 Any process that modulates the frequency, rate or extent of stomatal complex patterning. GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000049 Any process that activates or increases the frequency, rate or extent of cell-cell adhesion mediated by cadherin. CHEBI:85184 dihydroxycholanic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85184 CHEBI:85187 L-iduronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85187 CHEBI:85189 O-[(9Z)-hexadecenoyl]-L-serine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85189 GO:0061420 regulation of transcription from RNA polymerase II promoter in response to biotin starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061420 Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of biotin. GO:2000041 negative regulation of planar cell polarity pathway involved in axis elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000041 Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in axis elongation. GO:0036497 eIF2alpha dephosphorylation in response to endoplasmic reticulum stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036497 eIF2alpha dephosphorylation in response to ER stress|regulation of translation initiation by eIF2alpha dephosphorylation in response to endoplasmic reticulum stress The removal of a phosphate group from the translation initiation factor eIF2alpha, as a result of endoplasmic reticulum stress. GO:0036498 IRE1-mediated unfolded protein response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036498 IRE1alpha unfolded protein response|UPR signaling by IRE1 stress sensor|inositol-requiring transmembrane kinase/endonuclease signal transduction|IRE1 signaling in response to endoplasmic reticulum stress|IRE1 signal transduction pathway|inositol-requiring enzyme 1-mediated unfolded protein response|IRE1p unfolded protein response|endoplasmic reticulum unfolded protein response; IRE1 signaling|ERN1-mediated unfolded protein response|IRE1 branch of UPR A series of molecular signals mediated by the endoplasmic reticulum stress sensor IRE1 (Inositol-requiring transmembrane kinase/endonuclease). Begins with activation of IRE1 in response to endoplasmic reticulum (ER) stress, and ends with regulation of a downstream cellular process, e.g. transcription. One target of activated IRE1 is the transcription factor HAC1 in yeast, or XBP1 in mammals; IRE1 cleaves an intron of a mRNA coding for HAC1/XBP1 to generate an activated HAC1/XBP1 transcription factor, which controls the up regulation of UPR-related genes. At least in mammals, IRE1 can also signal through additional intracellular pathways including JNK and NF-kappaB. GO:0061421 positive regulation of transcription by oleic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061421 Any process involving oleic acid that activates or increases the rate of transcription. GO:2000042 negative regulation of double-strand break repair via homologous recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000042 negative regulation of HRR|negative regulation of Rad51-dependent recombinational repair|negative regulation of Rhp51-dependent recombinational repair|negative regulation of HDR|negative regulation of homologous recombinational repair|negative regulation of homology-directed repair Any process that stops, prevents, or reduces the frequency, rate or extent of double-strand break repair via homologous recombination. GO:2000043 regulation of cardiac cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000043 Any process that modulates the frequency, rate or extent of cardiac cell fate specification. GO:0061422 positive regulation of transcription from RNA polymerase II promoter in response to alkaline pH biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061422 positive regulation of transcription from RNA polymerase II promoter in response to alkalinity Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a pH >7.0. GO:0036499 PERK-mediated unfolded protein response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036499 UPR signaling by PERK stress sensor|PERK signaling in response to endoplasmic reticulum stress|PERK signal transduction pathway|endoplasmic reticulum unfolded protein response; PERK signaling|EIF2AK3-mediated unfolded protein response|PKR-like ER kinase signal transduction|PERK branch of UPR|eukaryotic translation initiation factor 2-alpha kinase 3-mediated unfolded protein response A series of molecular signals mediated by the endoplasmic reticulum membrane stress sensor PERK (PKR-like ER kinase). Begins with activation of PERK in response to endoplasmic reticulum (ER) stress and ends with regulation of a downstream cellular process, e.g. transcription. The main substrate of PERK is the translation initiation factor eIF2alpha. Serine-phosphorylation of eIF2alpha by PERK inactivates eIF2alpha and inhibits general protein translation. In addition, eIF2alpha phosphorylation preferentially increases the translation of selective mRNAs such as ATF4 (activating transcription factor 4), which up regulates a subset of UPR genes required to restore folding capacity. GO:2000044 negative regulation of cardiac cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000044 Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac cell fate specification. GO:0061423 positive regulation of sodium ion transport by positive regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061423 Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter resulting in the increased frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:2000045 regulation of G1/S transition of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000045 Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle. GO:0061424 obsolete positive regulation of peroxisome organization by positive regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061424 positive regulation of peroxisome organisation by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter and activates or increases the frequency, rate or extent of peroxisome organization. GO:2000046 obsolete regulation of G2 phase of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000046 regulation of G2 phase of mitotic cell cycle OBSOLETE. Any process that modulates the frequency, rate or extent of G2 phase of mitotic cell cycle. GO:0061425 positive regulation of ethanol catabolic process by positive regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061425 Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter and activates or increases the frequency, rate or extent of an ethanol catabolic process. GO:2000047 regulation of cell-cell adhesion mediated by cadherin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000047 Any process that modulates the frequency, rate or extent of cell-cell adhesion mediated by cadherin. GO:0061426 positive regulation of sulfite transport by positive regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061426 Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter and activates or increases the frequency, rate or extent of sulfite transport. GO:0061427 obsolete negative regulation of ceramide biosynthetic process by negative regulation of transcription from RNA Polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061427 OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter and stops, prevents or reduces the frequency, rate or extent of a ceramide biosynthetic process. GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000048 Any process that stops, prevents, or reduces the frequency, rate or extent of cell-cell adhesion mediated by cadherin. GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061428 Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus. GO:0036490 regulation of translation in response to endoplasmic reticulum stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036490 regulation of translation in response to ER stress Modulation of the frequency, rate or extent of translation as a result of endoplasmic reticulum stress. GO:0061429 positive regulation of transcription from RNA polymerase II promoter by oleic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061429 Any process involving oleic acid that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:0036491 regulation of translation initiation in response to endoplasmic reticulum stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036491 regulation of translation initiation in response to ER stress Any process that modulates the frequency, rate or extent of translation initiation, as a result of endoplasmic reticulum stress. GO:0036492 eiF2alpha phosphorylation in response to endoplasmic reticulum stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036492 eiF2alpha phosphorylation in response to ER stress|regulation of translation initiation by eiF2alpha phosphorylation in response to endoplasmic reticulum stress The addition of a phosphate group on to the translation initiation factor eIF2alpha, as a result of endoplasmic reticulum stress. GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036493 positive regulation of translation in response to ER stress Any process that activates, or increases the frequency, rate or extent of translation as a result of endoplasmic reticulum stress. GO:0036494 positive regulation of translation initiation in response to endoplasmic reticulum stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036494 positive regulation of translation initiation in response to ER stress Any process that activates, or increases the frequency, rate or extent of translation initiation as a result of endoplasmic reticulum stress. GO:0036495 negative regulation of translation initiation in response to endoplasmic reticulum stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036495 negative regulation of translation initiation in response to ER stress Any process that stops, prevents, or reduces the frequency, rate or extent of translation initiation as a result of endoplasmic reticulum stress. GO:2000040 regulation of planar cell polarity pathway involved in axis elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000040 Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in axis elongation. GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036496 Any process that modulates the frequency, rate or extent of translation initiation in response to stress by the dephosphorylation of eIF2 alpha. CHEBI:85171 sphingoid-1-phosphocholine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85171 GO:0120208 telodendria biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120208 Telodendria are projections that originate from the axon pedicle and form gap junctions with other neurons. CHEBI:85173 11-epi-prostaglandin F2alpha(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85173 CHEBI:85174 prostaglandin D2 ethanolamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85174 GO:0120209 cone telodendria biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120209 Cone telodendria are projections that originate from the cone pedicle and form gap junctions with other photoreceptors within the outer plexiform layer of the retina. CHEBI:85175 11beta-prostaglandin F2alpha ethanolamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85175 GO:0120204 methylcytosine to 5-glyceryl-methylcytosine dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0120204 Catalysis of the reaction: methylcytosine + L-ascorbate + O2 = 5-glyceryl-methylcytosine + glyoxylate + CO2. GO:0120205 photoreceptor proximal connecting cilium biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120205 photoreceptor PCC|PCC The proximal region of the photoreceptor connecting cilium is similar to the transition zone of unspecialized primary cilia and houses several major transition zone complexes, including NPHP, MKS, and RPGR. GO:0120206 photoreceptor distal connecting cilium biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120206 DCC|photoreceptor DCC The distal region of the photoreceptor connecting cilium is structurally unique to the photoreceptor and is maintained by retina-specific protein, SPATA7, and its interacting partners RPGR and RPGRIP1. It is essential for photoreceptor sensory cilium stability. GO:0120207 endocytosis, site selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0120207 The process of selecting and or marking the position where endocytosis will occur. GO:0036486 ventral trunk neural crest cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036486 ventral trunk NCC migration|trunk NCC migration within somite|trunk NCC migration through anterior sclerotome The movement of trunk neural crest cells from the neural tube, travelling ventrally through the anterior half of each sclerotome. Trunk neural crest cells that remain in the sclerotome form the dorsal root ganglia containing the sensory neurons. Trunk neural crest cells that continue more ventrally form the sympathetic ganglia, the adrenal medulla, and the nerve clusters surrounding the aorta. GO:2000052 positive regulation of non-canonical Wnt signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000052 positive regulation of non-canonical Wnt receptor signalling pathway|positive regulation of beta-catenin-independent Wnt receptor signaling pathway|positive regulation of non-canonical Wnt-activated signaling pathway|positive regulation of non-canonical Wnt receptor signaling pathway Any process that activates or increases the frequency, rate or extent of non-canonical Wnt-activated signaling pathway. GO:0120200 rod photoreceptor outer segment biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120200 The outer segment of a vertebrate rod photoreceptor that contains sealed membrane discs that are not connected to the ciliary membrane and containing rhodopsin photoreceptor proteins. GO:0036487 nitric-oxide synthase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036487 nitric oxide synthase inhibitor activity|NOS inhibitor activity Interacts with, and stops, prevents or reduces the activity of nitric oxide synthase. GO:0120201 cone photoreceptor disc membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120201 Stack of disc membranes located inside a cone photoreceptor outer segment, and containing densely packed molecules of opsin photoreceptor proteins that traverse the lipid bilayer. Cone disc membranes arise as evaginations of the ciliary membrane during the development of the cone outer segment and remain contiguous with the ciliary membrane. GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000053 regulation of Wnt-activated signaling pathway involved in dorsal/ventral axis specification|regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification|regulation of Wnt receptor signalling pathway involved in dorsal/ventral axis specification Any process that modulates the frequency, rate or extent of Wnt signaling pathway involved in dorsal/ventral axis specification. GO:0061410 positive regulation of transcription from RNA polymerase II promoter in response to ethanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061410 Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an ethanol stimulus. GO:0036488 CHOP-C/EBP complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0036488 CHOP-C/EBP heterodimer|GADD153-C/EBP complex|GADD153-C/EBP-alpha complex|CHOP-C/EBP dimer A heterodimeric protein complex that is composed of the transcription factor CHOP (GADD153) and a member of the C/EBP family of transcription factors. GO:0061411 positive regulation of transcription from RNA polymerase II promoter in response to cold biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061411 Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism. GO:0120202 rod photoreceptor disc membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120202 Stack of disc membranes located inside a rod photoreceptor outer segment, and containing densely packed molecules of rhodopsin photoreceptor proteins that traverse the lipid bilayer. It is thought that rod disc membranes arise as evaginations of the ciliary membrane near the base of the outer segment, which then become completely separated from the ciliary membrane, during the development of the rod outer segment. GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000054 negative regulation of Wnt receptor signalling pathway involved in dorsal/ventral axis specification|negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification|negative regulation of Wnt-activated signaling pathway involved in dorsal/ventral axis specification Any process that stops, prevents, or reduces the frequency, rate or extent of Wnt signaling pathway involved in dorsal/ventral axis specification. GO:0120203 rod photoreceptor disc lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0120203 The volume enclosed by the membrane of a rod photoreceptor cell disc membrane. GO:0036489 neuromelanin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036489 neuromelanin anabolism|neuromelanin biosynthesis|neuromelanin synthesis|neuromelanin formation The chemical reactions and pathways resulting in the formation of neuromelanin. Neuromelanin is a polymer of 5,6-dihydroxyindole monomers. GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000055 positive regulation of Wnt receptor signalling pathway involved in dorsal/ventral axis specification|positive regulation of Wnt-activated signaling pathway involved in dorsal/ventral axis specification|positive regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway involved in dorsal/ventral axis specification. GO:0061412 positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061412 Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of amino acids. GO:2000056 regulation of Wnt signaling pathway involved in digestive tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000056 regulation of Wnt receptor signaling pathway involved in digestive tract morphogenesis|regulation of Wnt receptor signalling pathway involved in digestive tract morphogenesis|regulation of Wnt-activated signaling pathway involved in digestive tract morphogenesis Any process that modulates the frequency, rate or extent of Wnt signaling pathway involved in digestive tract morphogenesis. GO:0061413 regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061413 A transcription regulation process in which the presence of a nonfermentable carbon source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources. GO:0061414 positive regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061414 A transcription regulation process in which the presence of a nonfermentable carbon source leads to an increase of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources. GO:2000057 negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000057 negative regulation of Wnt receptor signalling pathway involved in digestive tract morphogenesis|negative regulation of Wnt receptor signaling pathway involved in digestive tract morphogenesis|negative regulation of Wnt-activated signaling pathway involved in digestive tract morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of Wnt signaling pathway involved in digestive tract morphogenesis. GO:0061415 negative regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061415 A transcription regulation process in which the presence of a nonfermentable carbon source leads to a decrease of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources. GO:2000058 regulation of ubiquitin-dependent protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000058 regulation of protein degradation tagging activity|regulation of protein ubiquitination during ubiquitin-dependent protein catabolism|regulation of protein ubiquitylation during ubiquitin-dependent protein catabolic process|regulation of myofibrillar protein ubiquitination during ubiquitin-dependent protein degradation|regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|regulation of myofibrillar protein ubiquitination during ubiquitin-dependent protein breakdown|regulation of protein ubiquitination during ubiquitin-dependent protein degradation|regulation of myofibrillar protein ubiquitination during ubiquitin-dependent protein catabolic process|regulation of protein ubiquitination during ubiquitin-dependent protein breakdown|regulation of protein ubiquitylation during ubiquitin-dependent protein catabolism|regulation of myofibrillar protein ubiquitination during ubiquitin-dependent protein catabolism|regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolism|regulation of protein ubiquitination during ubiquitin-dependent protein catabolic process|regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolic process Any process that modulates the frequency, rate or extent of ubiquitin-dependent protein catabolic process. GO:2000059 negative regulation of ubiquitin-dependent protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000059 negative regulation of protein ubiquitylation during ubiquitin-dependent protein catabolism|negative regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolic process|negative regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolism|negative regulation of protein ubiquitylation during ubiquitin-dependent protein catabolic process|negative regulation of protein ubiquitination during ubiquitin-dependent protein degradation|negative regulation of protein ubiquitination during ubiquitin-dependent protein catabolism|negative regulation of protein ubiquitination during ubiquitin-dependent protein breakdown|negative regulation of protein ubiquitination during ubiquitin-dependent protein catabolic process|negative regulation of protein degradation tagging activity|negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin-dependent protein catabolic process. GO:0061416 obsolete regulation of transcription from RNA polymerase II promoter in response to salt stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061416 OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under salt stress. The stress is usually an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. GO:0061417 negative regulation of transcription from RNA polymerase II promoter in response to oxidative stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061417 Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061418 Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus. GO:0036480 neuron intrinsic apoptotic signaling pathway in response to oxidative stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036480 neuron apoptosis in response to oxidative stress|oxidative stress-induced neuronal apoptosis|oxidative stress-induced neuron apoptosis A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a neuron. The pathway is induced in response to oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, and ends when the execution phase of apoptosis is triggered. GO:0061419 positive regulation of transcription from RNA polymerase II promoter in response to hypoxia biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061419 Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus. GO:0036481 intrinsic apoptotic signaling pathway in response to hydrogen peroxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036481 intrinsic apoptotic signaling pathway in response to H2O2|H2O2-induced intrinsic apoptotic signaling pathway|hydrogen peroxide-induced intrinsic apoptotic signaling pathway|hydrogen peroxide-induced apoptosis A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to hydrogen peroxide (H2O2). GO:0036482 neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036482 hydrogen peroxide-induced neuronal apoptosis|neuron apoptosis in response to hydrogen peroxide|hydrogen peroxide-induced neuron apoptosis|H2O2-induced neuron intrinsic apoptotic signaling pathway|neuron intrinsic apoptotic signaling pathway in response to H2O2 A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a neuron in response to hydrogen peroxide. GO:0036483 neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036483 endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway|ER stress-induced neuron intrinsic apoptotic signaling pathway|endoplasmic reticulum stress-induced neuron apoptosis|ER stress-induced neuron apoptosis A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a neuron. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen. GO:2000050 regulation of non-canonical Wnt signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000050 regulation of beta-catenin-independent Wnt receptor signaling pathway|regulation of non-canonical Wnt-activated signaling pathway|regulation of non-canonical Wnt receptor signalling pathway|regulation of non-canonical Wnt receptor signaling pathway Any process that modulates the frequency, rate or extent of non-canonical Wnt signaling pathway. GO:0036484 trunk neural crest cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036484 trunk NCC migration The characteristic movement of trunk neural crest cells from the neural tube to other locations in the vertebrate embryo. GO:0036485 dorsolateral trunk neural crest cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036485 dorsolateral trunk NCC migration The movement of trunk neural crest cells from the neural tube, travelling dorso-laterally into the ectoderm and continuing toward the ventral midline of the belly. These migrating trunk neural crest cells become melanocytes, the melanin-forming pigment cells. GO:2000051 negative regulation of non-canonical Wnt signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000051 negative regulation of non-canonical Wnt receptor signalling pathway|negative regulation of beta-catenin-independent Wnt receptor signaling pathway|negative regulation of non-canonical Wnt-activated signaling pathway|negative regulation of non-canonical Wnt receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of non-canonical Wnt signaling pathway. CHEBI:26789 streptothricin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26789 CHEBI:75712 (S)-mecoprop biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75712 CHEBI:75717 (3R,4R)-3,4-dihydroxycyclohexa-1,5-diene-1-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75717 CHEBI:26787 streptomycin phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26787 CHEBI:75714 dUMP residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75714 CHEBI:26788 streptomycins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26788 CHEBI:36104 1,6-dihydroxycyclohexa-2,4-dienecarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36104 CHEBI:36105 (2R)-flavanone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36105 CHEBI:36102 (2R)-flavan biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36102 CHEBI:36103 (2S)-flavan biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36103 UBERON:0013525 stomach lumen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013525 cavity of stomach|gastric cavity The anatomical space that is enclosed by a stomach. CHEBI:36108 1-hydroxy-2-naphthoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36108 UBERON:0013526 otocyst lumen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013526 lumen of otocyst A anatomical cavity that is part of a ear vesicle. CHEBI:36109 piperidinecarboxylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36109 CHEBI:36106 2-naphthoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36106 CHEBI:36107 2-naphthoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36107 CHEBI:36100 (S)-isoflavan biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36100 CHEBI:36101 (R)-isoflavan biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36101 CHEBI:51737 alpha,beta-unsaturated carboxylic ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51737 CHEBI:75728 1-stearoyl-2-arachidonoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75728 CHEBI:51732 cycloheptatriene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51732 CHEBI:26799 styrenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26799 UBERON:0013522 subdivision of tube biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013522 CHEBI:75729 1-stearoyl-2-arachidonoyl-3-oleoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75729 CHEBI:36115 1H-isochromene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36115 CHEBI:36116 3H-isochromene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36116 CHEBI:36114 chromenylium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36114 UBERON:0013514 space surrounding organism biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013514 external to organism|outside of body The space that surrounds an organism. UBERON:0013515 subdivision of oviduct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013515 subdivision of uterine tube|subdivision of fallopian tube|zone of uterine tube|uterine tube zone|subdivision of oviduct A section through the tube or network of tubes that connects the ovaries to the outside of the body. CHEBI:36117 isochromene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36117 CHEBI:36112 pyridinedicarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36112 CHEBI:36110 pipecolate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36110 CHEBI:75735 1,3-dioleoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75735 CHEBI:26763 steroid glucosiduronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26763 CHEBI:26764 steroid hormone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26764 CHEBI:51720 ynal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_51720 CHEBI:51721 alpha,beta-unsaturated ketone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51721 CHEBI:26766 steroid lactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26766 CHEBI:26761 steroid antibiotic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26761 UBERON:0013507 thoracic vertebra cartilage element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013507 thoracic vertebral cartilage condensation group A thoracic vertebra endochondral element that is composed primarily of cartilage tissue. UBERON:0013508 thoracic vertebra pre-cartilage condensation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013508 A thoracic vertebra endochondral element that is composed primarily of a pre-cartilage condensation. UBERON:0013503 caudal vertebra cartilage element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013503 tail vertebral cartilage condensation|coccygeal vertebral cartilage condensation group|coccygeal vertebra cartilage element A caudal vertebra endochondral element that is composed primarily of cartilage tissue. UBERON:0013504 caudal vertebra pre-cartilage condensation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013504 coccygeal vertebra pre-cartilage condensation|tail vertebral pre-cartilage condensation A caudal vertebra endochondral element that is composed primarily of a pre-cartilage condensation. UBERON:0013505 cervical vertebra cartilage element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013505 cervical vertebral cartilage condensation group A cervical vertebra endochondral element that is composed primarily of cartilage tissue. CHEBI:566825 propan-1-aminium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_566825 UBERON:0013506 cervical vertebra pre-cartilage condensation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013506 A cervical vertebra endochondral element that is composed primarily of a pre-cartilage condensation. CHEBI:12154 5-oxohexanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_12154 CHEBI:75730 carminomycin(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75730 CHEBI:26775 stilbene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_26775 CHEBI:26776 stilbenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26776 UBERON:0013501 cloacal sphincter biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013501 sphincter cloacae A sphincter muscle that is part of a cloaca. UBERON:0013502 5th arch mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013502 5th pharyngeal arch mesenchyme|5th branchial arch mesenchyme|pharyngeal arch 5 mesenchyme A mesenchyme that is part of a pharyngeal arch 5. CHEBI:26773 stigmastane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_26773 CHEBI:51718 alpha,beta-unsaturated aldehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51718 CHEBI:61109 pyrimidine nucleotide-sugar biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61109 CHEBI:26745 spirostan biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_26745 CHEBI:75757 1-oleoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75757 CHEBI:51702 enoate ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_51702 CHEBI:51703 glyoxylate group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_51703 CHEBI:26747 squalene triterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26747 CHEBI:51704 glyoxylates biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_51704 CHEBI:26743 sphing-4-enine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26743 CHEBI:75759 beta-L-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75759 CHEBI:51705 octacarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51705 CHEBI:61111 aminophosphonate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61111 CHEBI:61112 methyl thiocyanate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61112 CHEBI:61115 EC 3.5.1.98 (histone deacetylase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61115 CHEBI:61114 N-(4-aminobenzoyl)-L-glutamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61114 CHEBI:61119 dTDP-rhamnose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61119 CHEBI:75767 animal metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75767 CHEBI:75768 mammalian metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75768 CHEBI:26759 sterigmatocystins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26759 CHEBI:75769 B vitamin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75769 CHEBI:61122 3-geranyl-4-hydroxybenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61122 CHEBI:61123 (E)-4-(trimethylammonio)but-2-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61123 CHEBI:61120 nucleobase-containing molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61120 CHEBI:61121 oxylipin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61121 CHEBI:61126 5,6,7,8-tetrahydropterin-6-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61126 CHEBI:61125 7-carboxy-7-deazaguanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61125 CHEBI:61129 N-hydroxy-L-isoleucine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61129 CHEBI:75763 eukaryotic metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75763 CHEBI:26725 glucitol phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26725 CHEBI:61130 hydroxy-L-isoleucine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61130 CHEBI:61133 N,N-dihydroxy-L-isoleucinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61133 CHEBI:85100 4,5-saturated-trans-2-enoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85100 CHEBI:61134 2-methylbutanal oxime biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61134 CHEBI:85101 trans,trans-2,4-dienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85101 CHEBI:61131 N-hydroxy-L-isoleucinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61131 CHEBI:61132 N,N-dihydroxy-L-isoleucine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61132 CHEBI:61138 N-hydroxy-L-valine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61138 CHEBI:61135 (E)-2-methylbutanal oxime biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61135 CHEBI:61136 (Z)-2-methylbutanal oxime biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61136 CHEBI:85108 trans-3-cis-5-octadienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85108 CHEBI:61139 hydroxy-L-valine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61139 CHEBI:12113 5-hydroxypenta-2,4-diene-1,2,5-tricarboxylate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_12113 CHEBI:75771 mouse metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75771 CHEBI:75772 Saccharomyces cerevisiae metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75772 CHEBI:26735 substituted spermine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26735 CHEBI:75787 prokaryotic metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75787 CHEBI:61140 N-hydroxy-L-valinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61140 CHEBI:61141 N,N-dihydroxy-L-valine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61141 CHEBI:61144 (Z)-2-methylpropanal oxime biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61144 CHEBI:12109 5-aminolevulinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_12109 CHEBI:61142 N,N-dihydroxy-L-valinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61142 CHEBI:61143 (E)-2-methylpropanal oxime biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61143 CHEBI:61148 drimenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61148 CHEBI:61149 2,3-dihydro-3-oxoanthranilic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61149 CHEBI:61146 4-nitrophenyl phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61146 CHEBI:61147 ferroheme d1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61147 CHEBI:26738 sphingenine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26738 CHEBI:26739 sphingolipid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26739 CHEBI:36191 hexenedioate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36191 CHEBI:36192 2-hexenedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36192 CHEBI:145844 PE(14:1_22:1) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145844 CHEBI:36190 hepoxilin A3 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36190 CHEBI:145847 PE(20:2_20:3) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145847 CHEBI:36188 malate ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36188 CHEBI:36186 cyclobutanedicarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36186 CHEBI:145832 sulfoquinovosyldiacylglycerol 26:5 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145832 CHEBI:145833 phosphatidylglycerol 27:2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145833 CHEBI:36194 cyclohexadienedicarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36194 CHEBI:36197 pyrandicarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36197 CHEBI:36166 5-[(1-carboxyethenyl)oxy]-6-hydroxycyclohexa-1,3-diene-1-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36166 CHEBI:36167 dipicolinate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36167 CHEBI:36164 amino dicarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36164 CHEBI:36165 pimelate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36165 CHEBI:36180 butenedioate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36180 CHEBI:36181 succinate ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36181 CHEBI:145813 D-cystine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_145813 CHEBI:36173 pyridinedicarboxylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36173 CHEBI:36174 octenedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36174 CHEBI:145814 EC 1.2.1.12 (aspartate-semialdehyde dehydrogenase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145814 CHEBI:51793 (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51793 CHEBI:36178 cytoporphyrins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36178 CHEBI:36175 octenedioate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36175 CHEBI:36148 4-hydroxy-2-oxoglutarate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36148 CHEBI:36149 2-hydroxyglutarate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36149 CHEBI:36147 oxo dicarboxylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36147 CHEBI:36140 cyclopentanones biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36140 CHEBI:36141 quinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36141 CHEBI:145806 (R)-(+)-perillyl alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_145806 CHEBI:36144 ferriheme b biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36144 CHEBI:36145 oxo dicarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36145 OBA:0006038 concentration of of calcium ion in cytosol biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0006038 cytosol calcium ion concentration of The concentration of of a calcium ion when measured in cytosol. CHEBI:36159 protoporphyrinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36159 CHEBI:36157 muconate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36157 CHEBI:36158 metalloprotoporphyrin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36158 CHEBI:12164 5-phosphoribosyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_12164 CHEBI:36126 cyclohexenecarboxylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36126 CHEBI:36124 (+)-quinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36124 CHEBI:36125 cyclitol carboxylic acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36125 CHEBI:36128 cyclopropanecarboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36128 CHEBI:36129 pentenedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36129 CHEBI:12195 6-O-(N-acetyl-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_12195 CHEBI:36123 cyclitol carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36123 CHEBI:36121 flavylium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36121 CHEBI:12194 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_12194 CHEBI:75700 (13R)-hydroxy-(14S,15S)-epoxyicosa-(5Z,8Z,11Z)-trienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75700 CHEBI:75705 D-glucosaminic acid 6-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75705 CHEBI:75703 (R)-mecoprop biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75703 CHEBI:75704 2-(4-chloro-2-methylphenoxy)propanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75704 CHEBI:36130 cyclic terpene ketone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36130 CHEBI:51750 alpha,beta-unsaturated carboxylic acid amide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51750 CHEBI:51751 enamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_51751 CHEBI:36133 pentenedioate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36133 CHEBI:36134 glutaconate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36134 CHEBI:36132 alicyclic ketone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36132 GO:1901329 regulation of odontoblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901329 Any process that modulates the frequency, rate or extent of odontoblast differentiation. GO:1901327 response to tacrolimus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901327 response to tacrolimus hydrate|response to FK506 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tacrolimus stimulus. GO:1901328 response to cytochalasin B biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901328 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytochalasin B stimulus. GO:1901325 response to antimycin A biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901325 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimycin A stimulus. GO:1901326 response to tetracycline biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901326 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetracycline stimulus. GO:1901323 response to erythromycin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901323 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythromycin stimulus. GO:1901324 response to trichodermin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901324 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichodermin stimulus. GO:1901321 positive regulation of heart induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901321 up-regulation of heart induction|upregulation of heart induction|up regulation of heart induction|activation of heart induction Any process that activates or increases the frequency, rate or extent of heart induction. GO:0061560 cranial ganglion formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061560 cranial ganglia formation The process that gives rise to a cranial ganglion. This process pertains to the initial formation of a structure from unspecified parts. GO:1901322 response to chloramphenicol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901322 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloramphenicol stimulus. GO:0061561 trigeminal ganglion formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061561 trigeminal ganglia formation The process that gives rise to the trigeminal ganglion. This process pertains to the initial formation of a structure from unspecified parts. GO:0061562 cranial ganglion structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061562 cranial ganglia structural organization The process that contributes to creating the structural organization of a cranial ganglion. This process pertains to the physical shaping of a rudimentary structure. GO:1901320 negative regulation of heart induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901320 inhibition of heart induction|down regulation of heart induction|downregulation of heart induction|down-regulation of heart induction Any process that stops, prevents or reduces the frequency, rate or extent of heart induction. GO:0061563 trigeminal ganglion structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061563 trigeminal ganglia organization The process that contributes to creating the structural organization of the trigeminal ganglion This process pertains to the physical shaping of a rudimentary structure. GO:0061564 axon development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061564 The progression of an axon over time. Covers axonogenesis (de novo generation of an axon) and axon regeneration (regrowth), as well as processes pertaining to the progression of the axon over time (fasciculation and defasciculation). GO:0061565 dAMP phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061565 The process of introducing a phosphate group into dAMP, deoxyadenosine monophosphate, to produce dADP. Addition of two phosphate groups produces dATP. GO:0061566 CMP phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061566 The process of introducing a phosphate group into CMP, cytidine monophosphate, to produce CDP. Addition of two phosphate groups produces CTP. GO:0061567 dCMP phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061567 The process of introducing a phosphate group into dCMP, deoxycytidine monophosphate, to produce dCDP. Addition of two phosphate groups produces dCTP. GO:0061568 GDP phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061568 The process of introducing a phosphate group into GDP, guanosine diphosphate, to produce GTP. GO:0061569 UDP phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061569 The process of introducing a phosphate group into UDP, uridine diphosphate, to produce UTP. GO:1901338 catecholamine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901338 Interacting selectively and non-covalently with catecholamine. CHEBI:85072 15-dehydroprostaglandin A1(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85072 CHEBI:85073 12-methyloctadecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85073 GO:1901339 regulation of store-operated calcium channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901339 Any process that modulates the frequency, rate or extent of store-operated calcium channel activity. GO:1901336 lactone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901336 lactone anabolism|lactone synthesis|lactone formation|lactone biosynthesis The chemical reactions and pathways resulting in the formation of lactone. CHEBI:85074 2-methylhexadecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85074 GO:1901337 thioester transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901337 The directed movement of a thioester into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:85075 3-methylundecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85075 GO:1901334 lactone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901334 lactone metabolism The chemical reactions and pathways involving lactone. CHEBI:85076 1-oleoyl-2-stearoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85076 GO:1901335 lactone catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901335 lactone catabolism|lactone degradation|lactone breakdown The chemical reactions and pathways resulting in the breakdown of lactone. CHEBI:85077 isomyristoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85077 GO:1901332 negative regulation of lateral root development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901332 inhibition of lateral root development|down-regulation of lateral root development|downregulation of lateral root development|down regulation of lateral root development Any process that stops, prevents or reduces the frequency, rate or extent of lateral root development. GO:1901333 positive regulation of lateral root development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901333 upregulation of lateral root development|activation of lateral root development|up-regulation of lateral root development|up regulation of lateral root development Any process that activates or increases the frequency, rate or extent of lateral root development. GO:1901330 negative regulation of odontoblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901330 down-regulation of odontoblast differentiation|inhibition of odontoblast differentiation|down regulation of odontoblast differentiation|downregulation of odontoblast differentiation Any process that stops, prevents or reduces the frequency, rate or extent of odontoblast differentiation. GO:0061550 cranial ganglion development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061550 cranial ganglia development The process whose specific outcome is the progression of a cranial ganglion over time, from its formation to the mature structure. GO:1901331 positive regulation of odontoblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901331 up regulation of odontoblast differentiation|activation of odontoblast differentiation|up-regulation of odontoblast differentiation|upregulation of odontoblast differentiation Any process that activates or increases the frequency, rate or extent of odontoblast differentiation. GO:0061551 trigeminal ganglion development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061551 trigeminal ganglia development The process whose specific outcome is the progression of a trigeminal ganglion over time, from its formation to the mature structure. GO:0061552 ganglion morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061552 ganglia morphogenesis The process in which the anatomical structures of ganglion are generated and organized. GO:1901340 negative regulation of store-operated calcium channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901340 down regulation of store-operated calcium channel activity|downregulation of store-operated calcium channel activity|down-regulation of store-operated calcium channel activity|inhibition of store-operated calcium channel activity Any process that stops, prevents or reduces the frequency, rate or extent of store-operated calcium channel activity. GO:0061553 ganglion maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061553 ganglia maturation A developmental process, independent of morphogenetic (shape) change, that is required for ganglion to attain its fully functional state. GO:0061554 ganglion formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061554 ganglia formation The process that gives rise to ganglion. This process pertains to the initial formation of a structure from unspecified parts. GO:0061555 ganglion structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061555 ganglia structural organization The process that contributes to creating the structural organization of a ganglion. This process pertains to the physical shaping of a rudimentary structure. GO:0061556 trigeminal ganglion morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061556 trigeminal ganglia morphogenesis The process in which the anatomical structure of a trigeminal ganglion is generated and organized. GO:0061557 trigeminal ganglion maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061557 trigeminal ganglia maturation A developmental process, independent of morphogenetic (shape) change, that is required for a trigeminal ganglion to attain its fully functional state. GO:0061558 cranial ganglion maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061558 cranial ganglia maturation A developmental process, independent of morphogenetic (shape) change, that is required for a cranial ganglion to attain its fully functional state. GO:0061559 cranial ganglion morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061559 cranial ganglia morphogenesis The process in which the anatomical structure of a cranial ganglion is generated and organized. GO:1901349 glucosinolate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901349 The directed movement of a glucosinolate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:1901347 negative regulation of secondary cell wall biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901347 negative regulation of secondary cell wall synthesis|down-regulation of secondary cell wall synthesis|down regulation of cellulose and pectin-containing secondary cell wall biogenesis|negative regulation of secondary cell wall formation|down-regulation of secondary cell wall formation|negative regulation of secondary cell wall biosynthetic process|down-regulation of secondary cell wall biosynthetic process|down-regulation of secondary cell wall biogenesis|inhibition of cellulose and pectin-containing secondary cell wall biogenesis|inhibition of secondary cell wall anabolism|inhibition of plant-type secondary cell wall biogenesis|inhibition of secondary cell wall synthesis|downregulation of secondary cell wall biosynthetic process|downregulation of secondary cell wall biogenesis|down regulation of secondary cell wall anabolism|inhibition of secondary cell wall formation|down regulation of plant-type secondary cell wall biogenesis|down regulation of secondary cell wall biosynthetic process|down regulation of secondary cell wall biogenesis|inhibition of secondary cell wall biogenesis|downregulation of secondary cell wall anabolism|down regulation of secondary cell wall synthesis|negative regulation of cellulose and pectin-containing secondary cell wall biogenesis|downregulation of plant-type secondary cell wall biogenesis|down-regulation of cellulose and pectin-containing secondary cell wall biogenesis|down regulation of secondary cell wall formation|downregulation of secondary cell wall synthesis|inhibition of secondary cell wall biosynthetic process|downregulation of secondary cell wall formation|negative regulation of secondary cell wall anabolism|down-regulation of secondary cell wall anabolism|down-regulation of plant-type secondary cell wall biogenesis|negative regulation of plant-type secondary cell wall biogenesis|downregulation of cellulose and pectin-containing secondary cell wall biogenesis Any process that stops, prevents or reduces the frequency, rate or extent of secondary cell wall biogenesis. GO:1901348 positive regulation of secondary cell wall biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901348 activation of secondary cell wall synthesis|up-regulation of secondary cell wall anabolism|activation of secondary cell wall biosynthetic process|upregulation of cellulose and pectin-containing secondary cell wall biogenesis|up-regulation of plant-type secondary cell wall biogenesis|activation of secondary cell wall formation|up-regulation of secondary cell wall synthesis|positive regulation of secondary cell wall biosynthetic process|up regulation of secondary cell wall biosynthetic process|up-regulation of secondary cell wall formation|up regulation of secondary cell wall biogenesis|upregulation of secondary cell wall anabolism|upregulation of plant-type secondary cell wall biogenesis|up-regulation of cellulose and pectin-containing secondary cell wall biogenesis|upregulation of secondary cell wall synthesis|upregulation of secondary cell wall formation|activation of cellulose and pectin-containing secondary cell wall biogenesis|upregulation of secondary cell wall biosynthetic process|upregulation of secondary cell wall biogenesis|up regulation of secondary cell wall anabolism|up regulation of plant-type secondary cell wall biogenesis|positive regulation of cellulose and pectin-containing secondary cell wall biogenesis|positive regulation of secondary cell wall anabolism|positive regulation of plant-type secondary cell wall biogenesis|up regulation of secondary cell wall synthesis|up regulation of cellulose and pectin-containing secondary cell wall biogenesis|positive regulation of secondary cell wall synthesis|up-regulation of secondary cell wall biosynthetic process|up regulation of secondary cell wall formation|activation of secondary cell wall anabolism|up-regulation of secondary cell wall biogenesis|activation of plant-type secondary cell wall biogenesis|activation of secondary cell wall biogenesis|positive regulation of secondary cell wall formation Any process that activates or increases the frequency, rate or extent of secondary cell wall biogenesis. GO:1901345 response to L-thialysine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901345 response to thialysine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-thialysine stimulus. GO:1901346 negative regulation of vasculature development involved in avascular cornea development in camera-type eye biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901346 downregulation of vascular system development involved in avascular cornea development|downregulation of vasculature development involved in avascular cornea development in camera-type eye|down regulation of vascular system development involved in avascular cornea development|negative regulation of vascular system development involved in avascular cornea development in camera-type eye|down-regulation of vascular system development involved in avascular cornea development in camera-type eye|down-regulation of vasculature development involved in avascular cornea development|negative regulation of vasculature development involved in avascular cornea development|inhibition of vascular system development involved in avascular cornea development|down-regulation of vasculature development involved in avascular cornea development in camera-type eye|inhibition of vasculature development involved in avascular cornea development in camera-type eye|downregulation of vasculature development involved in avascular cornea development|inhibition of vascular system development involved in avascular cornea development in camera-type eye|down regulation of vasculature development involved in avascular cornea development|negative regulation of vascular system development involved in avascular cornea development|down-regulation of vascular system development involved in avascular cornea development|inhibition of vasculature development involved in avascular cornea development|down regulation of vascular system development involved in avascular cornea development in camera-type eye|downregulation of vascular system development involved in avascular cornea development in camera-type eye|down regulation of vasculature development involved in avascular cornea development in camera-type eye Any negative regulation of vasculature development that is involved in developing an avascular cornea of a camera-type eye. GO:0061580 colon epithelial cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061580 The orderly movement of a colonic epithelial cell from one site to another, often during the development of a multicellular organism. GO:1901343 negative regulation of vasculature development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901343 negative regulation of vascular system development|down-regulation of vascular system development|down-regulation of vasculature development|inhibition of vasculature development|inhibition of vascular system development|down regulation of vascular system development|downregulation of vascular system development|down regulation of vasculature development|downregulation of vasculature development Any process that stops, prevents or reduces the frequency, rate or extent of vasculature development. GO:0061581 corneal epithelial cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061581 The orderly movement of a corneal epithelial cell from one site to another, often during the development of a multicellular organism. GO:0061582 intestinal epithelial cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061582 The orderly movement of an intestinal epithelial cell from one site to another, often during the development of a multicellular organism. GO:1901344 response to leptomycin B biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901344 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptomycin B stimulus. GO:0061583 colon epithelial cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061583 The directed movement of a colon epithelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). GO:1901341 positive regulation of store-operated calcium channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901341 up regulation of store-operated calcium channel activity|activation of store-operated calcium channel activity|up-regulation of store-operated calcium channel activity|upregulation of store-operated calcium channel activity Any process that activates or increases the frequency, rate or extent of store-operated calcium channel activity. GO:1901342 regulation of vasculature development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901342 regulation of vascular system development Any process that modulates the frequency, rate or extent of vasculature development. GO:0061584 hypocretin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061584 orexin secretion The controlled release of hypocretin from a cell or a tissue. GO:1901350 obsolete cell-cell signaling involved in cell-cell junction organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901350 cell-cell signalling involved in intercellular junction assembly and maintenance|cell-cell signaling involved in cell-cell junction assembly and maintenance|cell-cell signaling involved in intercellular junction assembly and maintenance|cell-cell signalling involved in cell-cell junction biogenesis|cell-cell signalling involved in cell-cell junction organisation|cell-cell signalling involved in cell-cell junction organization|cell-cell signaling involved in cell-cell junction biogenesis|cell-cell signaling involved in cell-cell junction organisation|cell-cell signalling involved in cell-cell junction assembly and maintenance OBSOLETE. Any cell-cell signaling that is involved in cell-cell junction organization. GO:0061585 hypocretin secretion, neurotransmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061585 orexin secretion, neurotransmission The controlled release of a peptide from a cell or a tissue in which the peptide acts as a neurotransmitter. GO:1901351 regulation of phosphatidylglycerol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901351 regulation of phosphatidylglycerol formation|regulation of phosphatidylglycerol biosynthesis|regulation of phosphatidylglycerol anabolism|regulation of phosphatidylglycerol synthesis Any process that modulates the frequency, rate or extent of phosphatidylglycerol biosynthetic process. GO:0061586 positive regulation of transcription by transcription factor localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061586 Any process that activates or increases the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the localization of a transcription factor. GO:0061587 transfer RNA gene-mediated silencing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061587 tRNA gene-mediated chromatin silencing|transfer RNA gene-mediated chromatin silencing|transfer RNA gene-mediated gene silencing|tgm silencing|tRNA gene-mediated gene silencing The chromatin silencing that results in the inhibition of RNA polymerase II-transcribed genes located in the vicinity of tRNA genes. GO:0061588 calcium activated phospholipid scrambling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061588 The movement of a population of phospholipid molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus. GO:0061589 calcium activated phosphatidylserine scrambling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061589 The movement of a population of phosphatidylserine molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus. CHEBI:9107 senecionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_9107 CHEBI:9100 Sem-tRNA(Met) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_9100 CHEBI:85090 (3E,5Z,8Z,11Z,14Z)-icosapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85090 CHEBI:85091 (2E,4E,8Z,11Z,14Z)-icosapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85091 GO:1901358 beta-D-galactofuranose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901358 beta-D-galactofuranose anabolism|beta-D-galactofuranose biosynthesis|beta-D-galactofuranose synthesis|beta-D-galactofuranose formation The chemical reactions and pathways resulting in the formation of beta-D-galactofuranose. CHEBI:85097 4-saturated trans-2-enoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85097 GO:1901359 tungstate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901359 Interacting selectively and non-covalently with tungstate. GO:1901356 beta-D-galactofuranose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901356 beta-D-galactofuranose metabolism The chemical reactions and pathways involving beta-D-galactofuranose. GO:1901357 beta-D-galactofuranose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901357 beta-D-galactofuranose catabolism|beta-D-galactofuranose degradation|beta-D-galactofuranose breakdown The chemical reactions and pathways resulting in the breakdown of beta-D-galactofuranose. CHEBI:85099 (2E,4Z)-dienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85099 GO:0061570 dCDP phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061570 The process of introducing a phosphate group into dCDP to produce a dCTP. GO:1901354 response to L-canavanine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901354 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-canavanine stimulus. GO:0061571 TDP phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061571 The process of introducing a phosphate group into TDP to produce a TTP. GO:1901355 response to rapamycin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901355 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rapamycin stimulus. GO:1901352 negative regulation of phosphatidylglycerol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901352 inhibition of phosphatidylglycerol synthesis|down regulation of phosphatidylglycerol formation|inhibition of phosphatidylglycerol formation|down regulation of phosphatidylglycerol biosynthetic process|down regulation of phosphatidylglycerol biosynthesis|downregulation of phosphatidylglycerol biosynthetic process|downregulation of phosphatidylglycerol biosynthesis|down-regulation of phosphatidylglycerol anabolism|negative regulation of phosphatidylglycerol anabolism|down-regulation of phosphatidylglycerol biosynthesis|down-regulation of phosphatidylglycerol biosynthetic process|negative regulation of phosphatidylglycerol synthesis|down-regulation of phosphatidylglycerol synthesis|negative regulation of phosphatidylglycerol biosynthesis|down-regulation of phosphatidylglycerol formation|negative regulation of phosphatidylglycerol formation|downregulation of phosphatidylglycerol anabolism|inhibition of phosphatidylglycerol biosynthetic process|inhibition of phosphatidylglycerol biosynthesis|down regulation of phosphatidylglycerol anabolism|downregulation of phosphatidylglycerol synthesis|inhibition of phosphatidylglycerol anabolism|downregulation of phosphatidylglycerol formation|down regulation of phosphatidylglycerol synthesis Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylglycerol biosynthetic process. GO:0061572 actin filament bundle organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061572 actin filament cable organization A process that results in the assembly, arrangement of constituent parts, or disassembly of an actin filament bundle. GO:1901353 positive regulation of phosphatidylglycerol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901353 upregulation of phosphatidylglycerol biosynthetic process|upregulation of phosphatidylglycerol biosynthesis|upregulation of phosphatidylglycerol synthesis|upregulation of phosphatidylglycerol formation|up-regulation of phosphatidylglycerol anabolism|activation of phosphatidylglycerol anabolism|up-regulation of phosphatidylglycerol synthesis|activation of phosphatidylglycerol synthesis|up regulation of phosphatidylglycerol biosynthetic process|up regulation of phosphatidylglycerol biosynthesis|activation of phosphatidylglycerol biosynthetic process|activation of phosphatidylglycerol biosynthesis|up-regulation of phosphatidylglycerol formation|positive regulation of phosphatidylglycerol biosynthesis|activation of phosphatidylglycerol formation|positive regulation of phosphatidylglycerol anabolism|up regulation of phosphatidylglycerol anabolism|positive regulation of phosphatidylglycerol synthesis|up regulation of phosphatidylglycerol synthesis|up-regulation of phosphatidylglycerol biosynthesis|up-regulation of phosphatidylglycerol biosynthetic process|positive regulation of phosphatidylglycerol formation|up regulation of phosphatidylglycerol formation|upregulation of phosphatidylglycerol anabolism Any process that activates or increases the frequency, rate or extent of phosphatidylglycerol biosynthetic process. GO:0061573 actin filament bundle retrograde transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061573 actin filament cable retrograde transport A process of actin filament bundle distribution that results in the arrangement of actin filament bundles from the periphery toward the interior of the cell. GO:1901361 organic cyclic compound catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901361 organic cyclic compound breakdown|organic cyclic compound catabolism|organic cyclic compound degradation The chemical reactions and pathways resulting in the breakdown of organic cyclic compound. GO:0061574 ASAP complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061574 A protein complex involved in regulation of mRNA processing and apoptosis. It binds to RNA in a sequence-independent manner and is recruited to the EJC prior to or during the splicing process. In humans the core proteins are RNPS1, SAP18 and ACIN1. GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061575 cyclin-dependent protein kinase 5 activator activity Binds to and increases the activity of a cyclin-dependent protein serine/threonine kinase. GO:1901362 organic cyclic compound biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901362 organic cyclic compound anabolism|organic cyclic compound synthesis|organic cyclic compound biosynthesis|organic cyclic compound formation The chemical reactions and pathways resulting in the formation of organic cyclic compound. GO:0061576 acyl-CoA ceramide synthase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061576 A protein complex that catalyzes the reaction acyl-CoA + sphingosine = CoA + N-acylsphingosine. In S. cerevisiae it contains three subunits: lag1, lac1 and lip1. GO:1901360 organic cyclic compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901360 organic cyclic compound metabolism The chemical reactions and pathways involving organic cyclic compound. GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061577 generation of L-type calcium current A process in which a calcium ion is transported from one side of a membrane to the other by means of a high voltage-gated calcium channel. GO:0061578 Lys63-specific deubiquitinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061578 Reactome:R-HSA-936381|Reactome:R-HSA-5691411|Reactome:R-HSA-5690856|Reactome:R-HSA-5357845|Reactome:R-HSA-741411|Reactome:R-HSA-5691431|Reactome:R-HSA-688136|Reactome:R-HSA-936390|Reactome:R-HSA-5691439|Reactome:R-HSA-5696547|Reactome:R-HSA-8869506 Hydrolysis of Lys63-Linked ubiquitin unit(s) from a ubiquitinated protein. GO:0061579 N-acyl homoserine lactone synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061579 EC:2.3.1.184|RHEA:10096 autoinducer-1 synthase Catalyzing the reaction: acyl-[acyl-carrier-protein] + S-adenosyl-L-methionine -> [acyl-carrier- protein] + S-methyl-5'-thioadenosine + N-acyl-L-homoserine lactone. GO:1901369 cyclic 2,3-bisphospho-D-glycerate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901369 cDPG biosynthesis|cyclic 2,3-diphosphoglycerate biosynthesis|cyclic 2,3-bisphospho-D-glyceric acid biosynthetic process|cyclic 2,3-bisphospho-D-glyceric acid anabolism|cyclic 2,3-bisphospho-D-glyceric acid biosynthesis|cyclic 2,3-bisphospho-D-glyceric acid synthesis|cyclic 2,3-bisphospho-D-glyceric acid formation The chemical reactions and pathways resulting in the formation of cyclic 2,3-bisphospho-D-glyceric acid. GO:1901367 response to L-cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901367 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-cysteine stimulus. GO:1901368 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1901368 GO:1901365 funalenone catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901365 funalenone catabolism|funalenone degradation|funalenone breakdown The chemical reactions and pathways resulting in the breakdown of funalenone. GO:1901366 funalenone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901366 funalenone biosynthesis|funalenone anabolism|funalenone synthesis|funalenone formation The chemical reactions and pathways resulting in the formation of funalenone. GO:1901363 heterocyclic compound binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901363 Interacting selectively and non-covalently with heterocyclic compound. GO:1901364 funalenone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901364 funalenone metabolism The chemical reactions and pathways involving funalenone. GO:1901372 obsolete trehalose biosynthetic process involved in ascospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901372 trehalose biosynthesis involved in ascospore formation|mycose biosynthesis involved in ascospore biosynthesis|mycose biosynthetic process involved in ascospore biosynthesis|trehalose anabolism involved in ascospore formation|trehalose formation involved in ascospore biosynthesis|mykose biosynthesis involved in ascospore formation|mykose biosynthetic process involved in ascospore formation|trehalose synthesis involved in ascospore formation|trehalose synthesis involved in ascospore biosynthesis|mykose biosynthesis involved in ascospore biosynthesis|mykose biosynthetic process involved in ascospore biosynthesis|trehalose formation involved in ascospore formation|trehalose anabolism involved in ascospore biosynthesis|mycose biosynthesis involved in ascospore formation|mycose biosynthetic process involved in ascospore formation|trehalose biosynthetic process involved in ascospore biosynthesis|trehalose biosynthesis involved in ascospore biosynthesis OBSOLETE. Any trehalose biosynthetic process that is involved in ascospore formation. GO:1901373 lipid hydroperoxide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901373 The directed movement of a lipid hydroperoxide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:1901370 response to glutathione biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901370 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glutathione stimulus. GO:1901371 regulation of leaf morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901371 Any process that modulates the frequency, rate or extent of leaf morphogenesis. CHEBI:9168 sirolimus biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_9168 GO:0061590 calcium activated phosphatidylcholine scrambling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061590 The movement of a population of phosphatidylcholine molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus. GO:1901378 organic heteropentacyclic compound biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901378 organic heteropentacyclic compound anabolism|organic heteropentacyclic compound synthesis|organic heteropentacyclic compound biosynthesis|organic heteropentacyclic compound formation The chemical reactions and pathways resulting in the formation of organic heteropentacyclic compound. GO:1901379 regulation of potassium ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901379 regulation of potassium ion membrane transport Any process that modulates the frequency, rate or extent of potassium ion transmembrane transport. GO:0061591 calcium activated galactosylceramide scrambling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061591 The movement of a population of galactosylceramide molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus. GO:1901376 organic heteropentacyclic compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901376 organic heteropentacyclic compound metabolism The chemical reactions and pathways involving organic heteropentacyclic compound. GO:0061592 phosphatidylserine exposure on osteoblast involved in bone mineralization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061592 A phospholipid scrambling process that results in the appearance of phosphatidylserine on the surface of osteoblasts, and contributes to bone mineralization. GO:1901377 organic heteropentacyclic compound catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901377 organic heteropentacyclic compound breakdown|organic heteropentacyclic compound catabolism|organic heteropentacyclic compound degradation The chemical reactions and pathways resulting in the breakdown of organic heteropentacyclic compound. GO:0061593 sulfoquinovose isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061593 Catalysis of the reaction sulfoquinovose = 6-deoxy-6-sulfofructose. GO:1901374 acetate ester transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901374 The directed movement of an acetate ester into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0061594 6-deoxy-6-sulfofructose kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061594 MetaCyc:RXN-15297|RHEA:40443|EC:2.7.1.184 Catalysis of the reaction 6-deoxy-6-sulfofructose + ATP = 6-deoxy-6-sulfofructose-1-phosphate + ADP. GO:1901375 acetate ester transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901375 Enables the transfer of an acetate ester from one side of a membrane to the other. GO:0061595 6-deoxy-6-sulfofructose-1-phosphate aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061595 Catalysis of the reaction 6-deoxy-6-sulfofructose-1-phosphate = 3-sulfolactaldehyde + dihydroxyacetone phosphate. GO:1901383 negative regulation of chorionic trophoblast cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901383 downregulation of chorionic trophoblast cell proliferation|down regulation of chorionic trophoblast cell proliferation|inhibition of chorionic trophoblast cell proliferation|down-regulation of chorionic trophoblast cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of chorionic trophoblast cell proliferation. GO:0061596 3-sulfolactaldehyde reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061596 MetaCyc:RXN-15299|RHEA:40511|EC:1.1.1.373 Catalysis of the reaction 2,3-dihydroxypropane-1-sulfonate + NAD+ = 3-sulfolactaldehyde + NADH + H+. GO:1901384 positive regulation of chorionic trophoblast cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901384 up regulation of chorionic trophoblast cell proliferation|upregulation of chorionic trophoblast cell proliferation|up-regulation of chorionic trophoblast cell proliferation|activation of chorionic trophoblast cell proliferation Any process that activates or increases the frequency, rate or extent of chorionic trophoblast cell proliferation. GO:0061597 obsolete cyclic pyranopterin monophosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061597 OBSOLETE. Catalysis of the reaction GTP = cyclic pyranopterin phosphate + diphosphate. GO:0061598 molybdopterin adenylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061598 RHEA:31331|EC:2.7.7.75 Catalysis of the reaction ATP + molybdopterin = diphosphate + adenylyl-molybdopterin. GO:1901381 positive regulation of potassium ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901381 up-regulation of potassium ion transmembrane transport|upregulation of potassium ion transmembrane transport|up regulation of potassium ion transmembrane transport|positive regulation of potassium ion membrane transport|activation of potassium ion transmembrane transport Any process that activates or increases the frequency, rate or extent of potassium ion transmembrane transport. GO:0061599 molybdopterin molybdotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061599 EC:2.10.1.1|Reactome:R-HSA-947531|RHEA:35047 Catalysis of the reaction adenylyl-molybdopterin + molybdate = molybdenum cofactor + AMP. GO:1901382 regulation of chorionic trophoblast cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901382 Any process that modulates the frequency, rate or extent of chorionic trophoblast cell proliferation. GO:1901380 negative regulation of potassium ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901380 down regulation of potassium ion transmembrane transport|downregulation of potassium ion transmembrane transport|negative regulation of potassium ion membrane transport|down-regulation of potassium ion transmembrane transport|inhibition of potassium ion transmembrane transport Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transport. CHEBI:145863 PG(16:0_16:1) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145863 CHEBI:36090 4-coumaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36090 CHEBI:9150 simvastatin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_9150 CHEBI:36091 cinnamates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36091 GO:1901389 negative regulation of transforming growth factor beta activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901389 down regulation of TGF-B activation|inhibition of TGFbeta activation|inhibition of TGFB activation|down regulation of TGF-beta activation|down regulation of L-TGF-beta activation|downregulation of transforming growth factor beta activation|inhibition of TGF-B activation|downregulation of TGF-beta activation|down regulation of TGFB activation|negative regulation of latent TGF-beta activation|down-regulation of latent TGF-beta activation|downregulation of L-TGF-beta activation|down regulation of transforming growth factor beta activation|inhibition of transforming growth factor beta activation|downregulation of TGFB activation|down-regulation of TGFbeta activation|negative regulation of TGFbeta activation|negative regulation of TGF-beta activation|down-regulation of TGF-beta activation|downregulation of latent TGF-beta activation|down-regulation of L-TGF-beta activation|negative regulation of L-TGF-beta activation|negative regulation of TGF-B activation|down-regulation of TGF-B activation|down-regulation of TGFB activation|down regulation of latent TGF-beta activation|negative regulation of TGFB activation|downregulation of TGFbeta activation|down regulation of TGFbeta activation|downregulation of TGF-B activation|inhibition of TGF-beta activation|inhibition of latent TGF-beta activation|down-regulation of transforming growth factor beta activation|inhibition of L-TGF-beta activation Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta activation. GO:1901387 positive regulation of voltage-gated calcium channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901387 activation of depolarization-activated voltage gated calcium channel activity|up regulation of voltage-sensitive calcium channel|upregulation of voltage-dependent calcium channel activity|positive regulation of depolarization-activated voltage-gated calcium channel|upregulation of depolarization-activated voltage-gated calcium channel activity|upregulation of depolarization-activated calcium channel|positive regulation of voltage-sensitive calcium channel|upregulation of voltage-gated calcium ion channel activity|up regulation of depolarization-activated voltage-gated calcium channel|up-regulation of voltage-gated calcium channel activity|activation of voltage-gated calcium channel activity|up-regulation of dihydropyridine-sensitive calcium channel activity|up-regulation of depolarization-activated voltage gated calcium channel activity|activation of voltage-sensitive calcium channel|upregulation of voltage gated calcium channel activity|up-regulation of voltage-dependent calcium channel activity|up-regulation of depolarization-activated calcium channel|activation of dihydropyridine-sensitive calcium channel activity|up regulation of depolarization-activated voltage-gated calcium channel activity|up-regulation of voltage-gated calcium ion channel activity|upregulation of depolarization-activated voltage-gated calcium channel|up-regulation of voltage-sensitive calcium channel|positive regulation of depolarization-activated voltage-gated calcium channel activity|upregulation of depolarization-activated voltage gated calcium channel activity|activation of voltage-dependent calcium channel activity|positive regulation of dihydropyridine-sensitive calcium channel activity|up-regulation of voltage gated calcium channel activity|activation of depolarization-activated calcium channel|up regulation of voltage-gated calcium channel activity|activation of voltage-gated calcium ion channel activity|up regulation of dihydropyridine-sensitive calcium channel activity|activation of depolarization-activated voltage-gated calcium channel activity|positive regulation of voltage-dependent calcium channel activity|positive regulation of depolarization-activated calcium channel|up-regulation of depolarization-activated voltage-gated calcium channel|activation of voltage gated calcium channel activity|upregulation of voltage-sensitive calcium channel|up regulation of voltage-dependent calcium channel activity|positive regulation of voltage-gated calcium ion channel activity|up regulation of depolarization-activated calcium channel|up regulation of depolarization-activated voltage gated calcium channel activity|up regulation of voltage-gated calcium ion channel activity|up-regulation of depolarization-activated voltage-gated calcium channel activity|positive regulation of depolarization-activated voltage gated calcium channel activity|upregulation of voltage-gated calcium channel activity|upregulation of dihydropyridine-sensitive calcium channel activity|positive regulation of voltage gated calcium channel activity|activation of depolarization-activated voltage-gated calcium channel|up regulation of voltage gated calcium channel activity Any process that activates or increases the frequency, rate or extent of voltage-gated calcium channel activity. GO:1901388 regulation of transforming growth factor beta activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901388 regulation of TGF-beta activation|regulation of L-TGF-beta activation|regulation of TGFB activation|regulation of latent TGF-beta activation|regulation of TGFbeta activation|regulation of TGF-B activation Any process that modulates the frequency, rate or extent of transforming growth factor beta activation. GO:1901385 regulation of voltage-gated calcium channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901385 regulation of voltage gated calcium channel activity|regulation of depolarization-activated voltage-gated calcium channel activity|regulation of depolarization-activated voltage-gated calcium channel|regulation of depolarization-activated voltage gated calcium channel activity|regulation of dihydropyridine-sensitive calcium channel activity|regulation of voltage-dependent calcium channel activity|regulation of voltage-sensitive calcium channel|regulation of depolarization-activated calcium channel|regulation of voltage-gated calcium ion channel activity Any process that modulates the frequency, rate or extent of voltage-gated calcium channel activity. GO:1901386 negative regulation of voltage-gated calcium channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901386 downregulation of voltage gated calcium channel activity|down regulation of voltage gated calcium channel activity|inhibition of voltage-dependent calcium channel activity|down regulation of depolarization-activated voltage-gated calcium channel activity|downregulation of depolarization-activated voltage-gated calcium channel|negative regulation of voltage-sensitive calcium channel|inhibition of depolarization-activated calcium channel|inhibition of voltage-gated calcium ion channel activity|down-regulation of voltage-sensitive calcium channel|downregulation of depolarization-activated voltage-gated calcium channel activity|down regulation of depolarization-activated voltage-gated calcium channel|inhibition of depolarization-activated voltage gated calcium channel activity|down-regulation of voltage-gated calcium channel activity|down-regulation of dihydropyridine-sensitive calcium channel activity|negative regulation of dihydropyridine-sensitive calcium channel activity|inhibition of voltage gated calcium channel activity|inhibition of depolarization-activated voltage-gated calcium channel|negative regulation of voltage-dependent calcium channel activity|down-regulation of voltage-dependent calcium channel activity|negative regulation of depolarization-activated voltage-gated calcium channel activity|down regulation of depolarization-activated voltage gated calcium channel activity|down-regulation of depolarization-activated voltage-gated calcium channel activity|down-regulation of depolarization-activated calcium channel|negative regulation of voltage-gated calcium ion channel activity|negative regulation of depolarization-activated calcium channel|inhibition of voltage-sensitive calcium channel|down-regulation of voltage-gated calcium ion channel activity|downregulation of voltage-gated calcium channel activity|downregulation of dihydropyridine-sensitive calcium channel activity|downregulation of depolarization-activated voltage gated calcium channel activity|negative regulation of voltage gated calcium channel activity|down-regulation of voltage gated calcium channel activity|down regulation of voltage-gated calcium channel activity|down regulation of dihydropyridine-sensitive calcium channel activity|downregulation of voltage-dependent calcium channel activity|inhibition of voltage-gated calcium channel activity|down regulation of voltage-sensitive calcium channel|downregulation of depolarization-activated calcium channel|downregulation of voltage-gated calcium ion channel activity|negative regulation of depolarization-activated voltage-gated calcium channel|down-regulation of depolarization-activated voltage-gated calcium channel|downregulation of voltage-sensitive calcium channel|inhibition of depolarization-activated voltage-gated calcium channel activity|down regulation of voltage-dependent calcium channel activity|negative regulation of depolarization-activated voltage gated calcium channel activity|down-regulation of depolarization-activated voltage gated calcium channel activity|down regulation of voltage-gated calcium ion channel activity|down regulation of depolarization-activated calcium channel|inhibition of dihydropyridine-sensitive calcium channel activity Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated calcium channel activity. GO:1901394 positive regulation of transforming growth factor beta1 activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901394 up regulation of TGFB1 activation|up regulation of transforming growth factor-beta1 activation|upregulation of L-TGF-beta 1 activation|up-regulation of latent-TGF-beta1 activation|positive regulation of transforming growth factor-beta1 activation|upregulation of transforming growth factor beta1 activation|up-regulation of TGFbeta 1 activation|activation of transforming growth factor-beta1 activation|up regulation of TGF-beta 1 activation|upregulation of TGFB1 activation|upregulation of latent-TGF-beta1 activation|up regulation of L-TGF-beta 1 activation|positive regulation of TGF-beta 1 activation|activation of TGFbeta 1 activation|positive regulation of L-TGF-beta 1 activation|up-regulation of transforming growth factor-beta1 activation|up regulation of transforming growth factor beta1 activation|activation of transforming growth factor beta1 activation|positive regulation of TGFbeta 1 activation|activation of TGF-beta 1 activation|activation of L-TGF-beta 1 activation|up regulation of TGFbeta 1 activation|up-regulation of TGFB1 activation|up regulation of latent-TGF-beta1 activation|positive regulation of latent-TGF-beta1 activation|up-regulation of TGF-beta 1 activation|upregulation of transforming growth factor-beta1 activation|up-regulation of L-TGF-beta 1 activation|activation of TGFB1 activation|up-regulation of transforming growth factor beta1 activation|activation of latent-TGF-beta1 activation|upregulation of TGFbeta 1 activation|positive regulation of TGFB1 activation|upregulation of TGF-beta 1 activation Any process that activates or increases the frequency, rate or extent of transforming growth factor beta1 activation. GO:0036530 protein deglycation, methylglyoxal removal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036530 protein deglycation of methylglyoxal-glycated protein The removal of methylglyoxal from a glycated protein, to form lactate and a deglycated protein. GO:0036531 glutathione deglycation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036531 The removal of a sugar or dicarbonyl from glycated glutathione. Glutathione is the tripeptide glutamylcysteinylglycine. GO:1901395 regulation of transforming growth factor beta2 activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901395 regulation of TGF-beta 2 activation|regulation of TGFB2 activation|regulation of TGFbeta 2 activation Any process that modulates the frequency, rate or extent of transforming growth factor beta2 activation. GO:1901392 regulation of transforming growth factor beta1 activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901392 regulation of TGF-beta 1 activation|regulation of TGFB1 activation|regulation of L-TGF-beta 1 activation|regulation of latent-TGF-beta1 activation|regulation of TGFbeta 1 activation|regulation of transforming growth factor-beta1 activation Any process that modulates the frequency, rate or extent of transforming growth factor beta1 activation. GO:1901393 negative regulation of transforming growth factor beta1 activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901393 down regulation of TGF-beta 1 activation|down regulation of L-TGF-beta 1 activation|downregulation of TGFB1 activation|downregulation of TGF-beta 1 activation|inhibition of latent-TGF-beta1 activation|down-regulation of transforming growth factor-beta1 activation|down regulation of transforming growth factor beta1 activation|negative regulation of transforming growth factor-beta1 activation|down regulation of TGFB1 activation|downregulation of L-TGF-beta 1 activation|downregulation of transforming growth factor beta1 activation|down-regulation of TGFbeta 1 activation|negative regulation of TGFbeta 1 activation|down regulation of latent-TGF-beta1 activation|inhibition of TGFB1 activation|negative regulation of TGF-beta 1 activation|down-regulation of TGF-beta 1 activation|down-regulation of L-TGF-beta 1 activation|negative regulation of L-TGF-beta 1 activation|downregulation of latent-TGF-beta1 activation|inhibition of transforming growth factor-beta1 activation|down-regulation of transforming growth factor beta1 activation|downregulation of TGFbeta 1 activation|down regulation of TGFbeta 1 activation|down regulation of transforming growth factor-beta1 activation|down-regulation of TGFB1 activation|inhibition of transforming growth factor beta1 activation|down-regulation of latent-TGF-beta1 activation|negative regulation of latent-TGF-beta1 activation|negative regulation of TGFB1 activation|inhibition of TGF-beta 1 activation|inhibition of L-TGF-beta 1 activation|downregulation of transforming growth factor-beta1 activation|inhibition of TGFbeta 1 activation Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta1 activation. GO:1901390 positive regulation of transforming growth factor beta activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901390 up-regulation of transforming growth factor beta activation|activation of transforming growth factor beta activation|activation of TGFB activation|positive regulation of TGF-B activation|up-regulation of TGF-beta activation|up-regulation of L-TGF-beta activation|up regulation of TGF-B activation|upregulation of latent TGF-beta activation|up-regulation of TGFB activation|upregulation of TGFbeta activation|upregulation of TGF-beta activation|up-regulation of latent TGF-beta activation|upregulation of L-TGF-beta activation|upregulation of TGF-B activation|up regulation of transforming growth factor beta activation|upregulation of TGFB activation|up-regulation of TGFbeta activation|activation of latent TGF-beta activation|up regulation of TGF-beta activation|up-regulation of TGF-B activation|up regulation of L-TGF-beta activation|activation of TGFbeta activation|positive regulation of latent TGF-beta activation|upregulation of transforming growth factor beta activation|positive regulation of TGF-beta activation|positive regulation of L-TGF-beta activation|up regulation of latent TGF-beta activation|up regulation of TGFB activation|activation of TGF-beta activation|activation of TGF-B activation|positive regulation of TGFB activation|positive regulation of TGFbeta activation|activation of L-TGF-beta activation|up regulation of TGFbeta activation Any process that activates or increases the frequency, rate or extent of transforming growth factor beta activation. CHEBI:36085 trihydroxybenzoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36085 CHEBI:36086 sulfonatobenzoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36086 CHEBI:36084 dihydroxybenzoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36084 CHEBI:36087 cinnamate ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36087 CHEBI:36088 thromboxanes A biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36088 CHEBI:145850 PE(20:3_20:3) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145850 CHEBI:145852 PE(18:4_22:2) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145852 CHEBI:9160 single-stranded DNA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_9160 CHEBI:145855 phosphatidylethanolamine 44:8 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145855 CHEBI:145856 PE(22:2_22:6) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145856 GO:0036527 peptidyl-arginine deglycation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036527 deglycation of N-acetylarginine The removal of a sugar or dicarbonyl from an arginine residue of a glycated protein. GO:0036528 peptidyl-lysine deglycation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036528 deglycation of N-acetyllysine The removal of a sugar or dicarbonyl from a lysine residue of a glycated protein. GO:0036529 protein deglycation, glyoxal removal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036529 protein deglycation of glyoxal-glycated protein The removal of glyoxal from a glycated protein, to form glycolate and a deglycated protein. GO:1901398 regulation of transforming growth factor beta3 activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901398 regulation of TGF-beta 3 activation|regulation of TGFB3 activation|regulation of TGFbeta 3 activation Any process that modulates the frequency, rate or extent of transforming growth factor beta3 activation. GO:1901399 negative regulation of transforming growth factor beta3 activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901399 inhibition of TGFbeta 3 activation|down regulation of TGF-beta 3 activation|downregulation of TGFB3 activation|down regulation of transforming growth factor beta3 activation|downregulation of TGF-beta 3 activation|down regulation of TGFB3 activation|downregulation of transforming growth factor beta3 activation|down-regulation of TGFbeta 3 activation|negative regulation of TGFbeta 3 activation|inhibition of TGFB3 activation|down-regulation of TGF-beta 3 activation|negative regulation of TGF-beta 3 activation|down-regulation of transforming growth factor beta3 activation|downregulation of TGFbeta 3 activation|down regulation of TGFbeta 3 activation|inhibition of transforming growth factor beta3 activation|negative regulation of TGFB3 activation|down-regulation of TGFB3 activation|inhibition of TGF-beta 3 activation Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta3 activation. GO:1901396 negative regulation of transforming growth factor beta2 activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901396 inhibition of TGFbeta 2 activation|down regulation of TGF-beta 2 activation|downregulation of TGFB2 activation|down regulation of transforming growth factor beta2 activation|downregulation of TGF-beta 2 activation|down regulation of TGFB2 activation|downregulation of transforming growth factor beta2 activation|negative regulation of TGFbeta 2 activation|down-regulation of TGFbeta 2 activation|inhibition of TGFB2 activation|down-regulation of TGF-beta 2 activation|negative regulation of TGF-beta 2 activation|down-regulation of transforming growth factor beta2 activation|downregulation of TGFbeta 2 activation|inhibition of transforming growth factor beta2 activation|down regulation of TGFbeta 2 activation|negative regulation of TGFB2 activation|down-regulation of TGFB2 activation|inhibition of TGF-beta 2 activation Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta2 activation. GO:1901397 positive regulation of transforming growth factor beta2 activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901397 positive regulation of TGFB2 activation|upregulation of TGF-beta 2 activation|up regulation of TGFB2 activation|upregulation of transforming growth factor beta2 activation|up-regulation of TGFbeta 2 activation|up regulation of TGF-beta 2 activation|upregulation of TGFB2 activation|activation of TGFbeta 2 activation|positive regulation of TGF-beta 2 activation|up regulation of transforming growth factor beta2 activation|activation of transforming growth factor beta2 activation|positive regulation of TGFbeta 2 activation|activation of TGF-beta 2 activation|up regulation of TGFbeta 2 activation|up-regulation of TGFB2 activation|up-regulation of TGF-beta 2 activation|activation of TGFB2 activation|up-regulation of transforming growth factor beta2 activation|upregulation of TGFbeta 2 activation Any process that activates or increases the frequency, rate or extent of transforming growth factor beta2 activation. GO:0036520 astrocyte-dopaminergic neuron signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036520 mesencephalic dopaminergic neuron-astrocyte crosstalk|dopaminergic neuron-astrocyte crosstalk|astrocyte-dopaminergic neuron cell signaling|midbrain dopaminergic neuron-astrocyte crosstalk Cell-cell signaling that mediates the transfer of information from an astrocyte to a dopaminergic neuron. GO:0036521 modulation by symbiont of host protein localization to phagocytic vesicle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036521 modulation by symbiont of host protein localisation to phagosome Any process in which an organism modulates the frequency, rate or extent of protein localisation to the host phagosome. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0036522 negative regulation by symbiont of host protein localization to phagocytic vesicle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036522 inhibition of host protein localisation to phagosome|suppression of host protein localisation to phagosome|disruption of host protein localisation to phagosome Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of protein localisation to the host phagosome. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0036523 induction by symbiont of host cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036523 positive regulation by symbiont of host cytokine secretion|'induction by symbiont of host cytokine secretion'|induction by symbiont of host cytokine secretion Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of cytokine production by the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0036524 protein deglycase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0036524 MetaCyc:RXN-17634|MetaCyc:RXN-17632|MetaCyc:RXN-17630 protein deglycating enzyme Catalysis of the removal of a sugar or dicarbonyl from a lysine residue of a glycated protein. GO:0036525 protein deglycation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036525 glycated protein repair The removal of a sugar or dicarbonyl from a glycated protein. GO:0036526 peptidyl-cysteine deglycation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0036526 deglycation of N-acetylcysteine The removal of a sugar or dicarbonyl from a cysteine residue of a glycated protein. CHEBI:36096 cyclohexanecarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36096 CHEBI:36094 organic chloride salt biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36094 CHEBI:61032 5,6,7,8-tetrahydropterin-6-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61032 CHEBI:85004 sphingadienine-1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85004 CHEBI:85005 anticapsin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85005 CHEBI:85006 N(1),N(8)-bis(sinapoyl)-spermidine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85006 CHEBI:85007 N(1),N(8)-bis(coumaroyl)spermidine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85007 CHEBI:61036 7-carboxylato-7-deazaguanine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61036 CHEBI:85008 trans-4-coumaroyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85008 CHEBI:26706 sn-glycerol 3-phosphates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26706 CHEBI:26707 glycerol phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26707 CHEBI:26708 sodium atom biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_26708 CHEBI:26712 sodium molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26712 CHEBI:75688 1,3-dipalmitoyl-2-oleoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75688 CHEBI:26714 sodium salt biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26714 PR:000013883 renin biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000013883 angiotensinogenase|REN A protein that is a translation product of the human REN gene or a 1:1 ortholog thereof. CHEBI:61042 1-hexadecanoyl-2-(9-oxononanoyl)-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61042 CHEBI:61049 tacrolimus (anhydrous) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61049 CHEBI:61048 ganglioside GM1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61048 CHEBI:9192 solavetivone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_9192 NCBITaxon:10239 Viruses organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_10239 Vira|Viridae|viruses CHEBI:61050 alkyl hydroperoxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61050 CHEBI:61051 lipid hydroperoxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61051 CHEBI:61057 tacrolimus hydrate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61057 CHEBI:85027 2'-phospho-nucleotide 5'-phosphate(3-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85027 CHEBI:566789 ethylaminium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_566789 GO:0061500 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0061500 GO:0061501 cyclic-GMP-AMP synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061501 RHEA:35647|Reactome:R-HSA-3244614 Catalysis of the reaction: ATP + GTP = 2 diphosphate + cyclic GMP-AMP. GO:0061502 early endosome to recycling endosome transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061502 The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the recycling endosomes. CHEBI:75690 (8R)-hydroxy-(11R,12R)-epoxyicosa-(5Z,9E,14Z)-trienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75690 GO:0061503 tRNA threonylcarbamoyladenosine dehydratase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061503 Catalysis of the ATP-dependent dehydration of t6A to form cyclic t6A. GO:0061504 cyclic threonylcarbamoyladenosine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061504 The chemical reactions and pathways resulting in the formation of cyclic threonylcarbamoyladenosine, a modified nucleoside found in some tRNA molecules. GO:0061505 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0061505 GO:0061506 obsolete DNA topoisomerase type II (ATP-independent) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061506 OBSOLETE. Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is not coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2. GO:0061507 cyclic-GMP-AMP binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061507 Interacting selectively and non-covalently with cyclic-GMP-AMP (cGAMP) cyclic nucleotide. GO:0061508 CDP phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061508 The process of introducing a phosphate group into CDP to produce a CTP. CHEBI:75692 (8R)-hydroxy-(11S,12S)-epoxyicosa-(5Z,9E,14Z)-trienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75692 GO:0061509 asymmetric protein localization to old mitotic spindle pole body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061509 Any process in which a protein is transported to, or maintained to the old mitotic spindle pole body resulting in its being distributed asymmetrically. CHEBI:75696 (10R)-hydroxy-(11S,12S)-epoxyicosa-(5Z,8Z,14Z)-trienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75696 CHEBI:85011 EC 2.6.1.16 (glutamine--fructose-6-phosphate transaminase (isomerizing)) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85011 CHEBI:85040 (3R)-3,6-diaminohexanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85040 CHEBI:61073 oxygen radical biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61073 CHEBI:61078 purine nucleoside bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61078 CHEBI:61079 ribonucleoside bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61079 CHEBI:85046 skin lightening agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85046 CHEBI:85048 EC 1.10.3.* (oxidoreductase acting on diphenols and related substances as donors with oxygen as acceptor) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85048 CHEBI:85049 EC 1.10.3.1 (catechol oxidase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85049 GO:0061520 Langerhans cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061520 The process in which a precursor cell type acquires the specialized features of a Langerhans cell. GO:0061521 hepatic stellate cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061521 The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a hepatic stellate cell. GO:0061522 1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061522 Catalysis of the reaction 1,4-dihydroxy-2-naphthoyl-CoA + H2O = 1,4-dihydroxy-2-naphthoate + CoA. GO:0061523 cilium disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061523 cilium resorption A cellular process that results in the breakdown of a cilium. GO:0061524 central canal development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061524 The process whose specific outcome is the formation of the central canal of the spinal cord from its formation to the mature structure. The central canal is a spinal cord structure that is part of the ventricular system and is filled with cerebral-spinal fluid and runs the length of the spinal cord. GO:0061525 hindgut development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061525 The process whose specific outcome is the progression of the hindgut over time, from its formation to the mature structure. The hindgut is part of the alimentary canal that lies posterior to the midgut. GO:0061526 acetylcholine secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061526 The regulated release of acetylcholine by a cell. GO:0061527 dopamine secretion, neurotransmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061527 The regulated release of dopamine by a cell in which the dopamine acts as a neurotransmitter. GO:0061528 aspartate secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061528 The regulated release of aspartate by a cell. GO:0061529 epinephrine secretion, neurotransmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061529 adrenaline secretion, neurotransmission The regulated release of epinephrine by a cell in which the epinephrine acts as a neurotransmitter. CHEBI:61081 bis(5'-nucleosidyl) oliogophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61081 CHEBI:61082 lipid-linked peptidoglycan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61082 CHEBI:61085 3-sulfino-L-alanine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61085 CHEBI:85033 cobalt(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85033 CHEBI:85035 methyl-Co(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85035 GO:0061510 asymmetric protein localization to new mitotic spindle pole body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061510 Any process in which a protein is transported to, or maintained to the new mitotic spindle pole body resulting in its being distributed asymmetrically. GO:0061511 centriole elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061511 The centrosome organization process by which a centriole increases in length as part of the process of replication. GO:0061512 protein localization to cilium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061512 A process in which a protein is transported to, or maintained in, a location within a cilium. GO:0061513 glucose 6-phosphate:inorganic phosphate antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061513 Reactome:R-HSA-3229118|Reactome:R-HSA-198513|Reactome:R-HSA-3257122 glucose 6-phosphate:phosphate antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose 6-phosphate(out) + inorganic phosphate(in) = glucose 6-phosphate(in) + inorganic phosphate(out). GO:0061514 interleukin-34-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061514 A series of molecular signals initiated by the binding of interleukin-34 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0061515 myeloid cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061515 The process whose specific outcome is the progression of a myeloid cell over time, from its formation to the mature structure. GO:0061516 monocyte proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061516 The expansion of a monocyte population by cell division. GO:0061517 macrophage proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061517 The expansion of a macrophage population by cell division. GO:0061518 microglial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061518 The expansion of a microglial cell population by cell division. GO:0061519 macrophage homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061519 The process of regulating the proliferation and elimination of macrophage cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. GO:1901309 negative regulation of sterol regulatory element binding protein cleavage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901309 downregulation of SREBP cleavage|down regulation of sterol regulatory element binding protein cleavage|inhibition of sterol regulatory element binding protein cleavage|down regulation of SREBP cleavage|inhibition of SREBP processing|inhibition of SREBP cleavage|down-regulation of sterol regulatory element binding protein cleavage|down-regulation of SREBP cleavage|negative regulation of SREBP cleavage|downregulation of sterol regulatory element binding protein cleavage Any process that stops, prevents or reduces the frequency, rate or extent of sterol regulatory element binding protein cleavage. GO:1901307 positive regulation of spermidine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901307 up regulation of spermidine synthesis|positive regulation of spermidine formation|activation of spermidine biosynthesis|up regulation of spermidine formation|upregulation of spermidine anabolism|up-regulation of spermidine biosynthetic process|up-regulation of spermidine biosynthesis|upregulation of spermidine synthesis|upregulation of spermidine formation|up-regulation of spermidine anabolism|upregulation of spermidine biosynthesis|upregulation of spermidine biosynthetic process|up-regulation of spermidine synthesis|activation of spermidine anabolism|up-regulation of spermidine formation|activation of spermidine synthesis|positive regulation of spermidine anabolism|up regulation of spermidine biosynthetic process|up regulation of spermidine biosynthesis|up regulation of spermidine anabolism|activation of spermidine formation|positive regulation of spermidine biosynthesis|activation of spermidine biosynthetic process|positive regulation of spermidine synthesis Any process that activates or increases the frequency, rate or extent of spermidine biosynthetic process. GO:1901308 regulation of sterol regulatory element binding protein cleavage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901308 regulation of SREBP cleavage Any process that modulates the frequency, rate or extent of sterol regulatory element binding protein cleavage. GO:1901305 negative regulation of spermidine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901305 negative regulation of spermidine biosynthesis|down-regulation of spermidine biosynthesis|down-regulation of spermidine biosynthetic process|downregulation of spermidine synthesis|down regulation of spermidine anabolism|downregulation of spermidine formation|down regulation of spermidine synthesis|inhibition of spermidine biosynthetic process|inhibition of spermidine anabolism|down regulation of spermidine formation|inhibition of spermidine biosynthesis|inhibition of spermidine synthesis|inhibition of spermidine formation|down regulation of spermidine biosynthesis|down regulation of spermidine biosynthetic process|down-regulation of spermidine anabolism|negative regulation of spermidine anabolism|downregulation of spermidine biosynthetic process|downregulation of spermidine biosynthesis|negative regulation of spermidine synthesis|down-regulation of spermidine synthesis|down-regulation of spermidine formation|negative regulation of spermidine formation|downregulation of spermidine anabolism Any process that stops, prevents or reduces the frequency, rate or extent of spermidine biosynthetic process. GO:1901303 negative regulation of cargo loading into COPII-coated vesicle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901303 negative regulation of COPII coat-cargo complex assembly|down-regulation of COPII coat-cargo complex assembly|down-regulation of cargo selection into COPII-coated vesicle|negative regulation of cargo selection into COPII-coated vesicle|down regulation of cargo loading into COPII-coated vesicle|down-regulation of cargo loading into COPII vesicle|downregulation of cargo loading into COPII-coated vesicle|negative regulation of cargo loading into COPII vesicle|inhibition of COPII coat-cargo complex assembly|inhibition of COPII vesicle protein binding|inhibition of cargo selection into COPII-coated vesicle|downregulation of cargo loading into COPII vesicle|down-regulation of cargo loading into COPII-coated vesicle|inhibition of protein sorting into COPII-coated vesicles|down regulation of COPII coat-cargo complex assembly|down regulation of cargo selection into COPII-coated vesicle|down regulation of cargo loading into COPII vesicle|downregulation of COPII coat-cargo complex assembly|downregulation of cargo selection into COPII-coated vesicle|inhibition of cargo loading into COPII-coated vesicle|inhibition of cargo loading into COPII vesicle Any process that stops, prevents or reduces the frequency, rate or extent of cargo loading into a COPII-coated vesicle. GO:1901304 regulation of spermidine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901304 regulation of spermidine anabolism|regulation of spermidine synthesis|regulation of spermidine formation|regulation of spermidine biosynthesis Any process that modulates the frequency, rate or extent of spermidine biosynthetic process. GO:1901301 regulation of cargo loading into COPII-coated vesicle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901301 regulation of cargo loading into COPII vesicle|regulation of COPII coat-cargo complex assembly|regulation of cargo selection into COPII-coated vesicle Any process that modulates the frequency, rate or extent of cargo loading into COPII-coated vesicle. GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901300 up-regulation of hydrogen peroxide-mediated programmed cell death|activation of hydrogen peroxide-mediated programmed cell death|up regulation of hydrogen peroxide-mediated programmed cell death|upregulation of hydrogen peroxide-mediated programmed cell death Any process that activates or increases the frequency, rate or extent of hydrogen peroxide-mediated programmed cell death. GO:0061540 octopamine secretion, neurotransmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061540 The controlled release of octopamine by a cell, in which the octopamine acts as a neurotransmitter. GO:0061541 rhabdomere morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061541 The process in which the anatomical structures of a rhabdomere are generated and organized. The rhabdomere is the organelle on the apical surface of a photoreceptor cell that contains the visual pigments. GO:0061542 3-demethylubiquinol-n 3-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061542 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone methyltransferase|5-demethylubiquinone-9 methyltransferase|S-adenosyl-L-methionine:2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone-O-methyltransferase|5-demethylubiquinone-10 methyltransferase|OMHMB-methyltransferase Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinol-n = S-adenosyl-L-homocysteine + ubiquinol-n. GO:0061543 3-demethylubiquinol-6 3-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061543 Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinol-6 = S-adenosyl-L-homocysteine + ubiquinol-6. GO:0061544 peptide secretion, neurotransmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061544 The controlled release of a peptide from a cell in which the peptide acts as a neurotransmitter. GO:0061545 tyramine secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061545 The regulated release of a tyramine by a cell. GO:0061546 tyramine secretion, neurotransmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061546 The regulated release of a tyramine by a cell in which the tyramine acts as a neurotransmitter. GO:0061547 glycogen synthase activity, transferring glucose-1-phosphate biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061547 Reactome:R-HSA-3781024|Reactome:R-HSA-3780994 Catalysis of the reaction: UDP-glucose + (1,4)-alpha-D-glucosyl(n) = UMP + (1,4)-alpha-D-glucosyl(n)-glucose-1-phosphate. GO:0061548 ganglion development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061548 gangliogenesis|ganglia development The process whose specific outcome is the progression of a ganglion over time, from its formation to the mature structure. GO:0061549 sympathetic ganglion development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061549 sympathetic ganglia development The process whose specific outcome is the progression of a sympathetic ganglion over time, from its formation to the mature structure. GO:1901318 negative regulation of flagellated sperm motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901318 down regulation of sperm motility|negative regulation of sperm motility|downregulation of sperm movement|down regulation of sperm movement|inhibition of sperm movement|down-regulation of sperm motility|inhibition of sperm motility|downregulation of sperm motility|negative regulation of sperm movement|down-regulation of sperm movement Any process that stops, prevents or reduces the frequency, rate or extent of flagellated sperm motility. GO:1901319 positive regulation of trehalose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901319 positive regulation of trehalose breakdown|activation of trehalose degradation|up regulation of trehalose catabolic process|positive regulation of mykose catabolic process|activation of trehalose catabolism|activation of trehalose catabolic process|up regulation of mykose catabolic process|upregulation of mycose catabolism|activation of trehalose breakdown|up-regulation of trehalose degradation|upregulation of mycose catabolic process|up regulation of mykose catabolism|positive regulation of trehalose catabolism|positive regulation of mykose catabolism|up regulation of trehalose catabolism|up-regulation of trehalose breakdown|activation of mykose catabolism|up regulation of mycose catabolism|upregulation of mykose catabolic process|up-regulation of trehalose catabolic process|upregulation of trehalose degradation|up-regulation of mycose catabolic process|positive regulation of mycose catabolism|upregulation of trehalose catabolism|up-regulation of mykose catabolism|upregulation of trehalose breakdown|activation of mycose catabolic process|activation of mycose catabolism|up-regulation of mykose catabolic process|upregulation of trehalose catabolic process|up regulation of trehalose degradation|positive regulation of trehalose degradation|positive regulation of mycose catabolic process|up-regulation of mycose catabolism|up regulation of mycose catabolic process|upregulation of mykose catabolism|up-regulation of trehalose catabolism|up regulation of trehalose breakdown|activation of mykose catabolic process Any process that activates or increases the frequency, rate or extent of trehalose catabolic process. GO:1901316 positive regulation of histone H2A K63-linked ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901316 upregulation of histone H2A K63-linked ubiquitination|up regulation of histone H2A K63-linked ubiquitination|activation of histone H2A K63-linked ubiquitination|up-regulation of histone H2A K63-linked ubiquitination Any process that activates or increases the frequency, rate or extent of histone H2A K63-linked ubiquitination. CHEBI:85050 EC 1.10.3.2 (laccase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85050 GO:1901317 regulation of flagellated sperm motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901317 regulation of sperm movement|regulation of sperm motility Any process that modulates the frequency, rate or extent of flagellated sperm motility. CHEBI:85051 EC 1.13.11.24 (quercetin 2,3-dioxygenase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85051 CHEBI:85052 EC 1.4.3.3 (D-amino-acid oxidase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85052 GO:1901314 regulation of histone H2A K63-linked ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901314 Any process that modulates the frequency, rate or extent of histone H2A K63-linked ubiquitination. GO:1901315 negative regulation of histone H2A K63-linked ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901315 down regulation of histone H2A K63-linked ubiquitination|downregulation of histone H2A K63-linked ubiquitination|down-regulation of histone H2A K63-linked ubiquitination|inhibition of histone H2A K63-linked ubiquitination Any process that stops, prevents or reduces the frequency, rate or extent of histone H2A K63-linked ubiquitination. GO:1901312 obsolete negative regulation of gene expression involved in extracellular matrix organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901312 down regulation of extracellular matrix protein production|downregulation of gene expression involved in extracellular matrix organization|down regulation of expression of extracellular matrix proteins|downregulation of extracellular matrix protein production|downregulation of expression of extracellular matrix proteins|down-regulation of gene expression involved in extracellular matrix organization|down-regulation of extracellular matrix protein production|negative regulation of extracellular matrix protein production|down-regulation of expression of extracellular matrix proteins|negative regulation of expression of extracellular matrix proteins|inhibition of gene expression involved in extracellular matrix organization|inhibition of extracellular matrix protein production|inhibition of expression of extracellular matrix proteins|down regulation of gene expression involved in extracellular matrix organization OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of gene expression involved in extracellular matrix organization. GO:1901313 obsolete positive regulation of gene expression involved in extracellular matrix organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901313 upregulation of expression of extracellular matrix proteins|up regulation of gene expression involved in extracellular matrix organization|activation of gene expression involved in extracellular matrix organization|up regulation of extracellular matrix protein production|positive regulation of extracellular matrix protein production|up regulation of expression of extracellular matrix proteins|positive regulation of expression of extracellular matrix proteins|activation of extracellular matrix protein production|activation of expression of extracellular matrix proteins|up-regulation of gene expression involved in extracellular matrix organization|up-regulation of extracellular matrix protein production|up-regulation of expression of extracellular matrix proteins|upregulation of gene expression involved in extracellular matrix organization|upregulation of extracellular matrix protein production OBSOLETE. Any process that activates or increases the frequency, rate or extent of gene expression involved in extracellular matrix organization. GO:1901310 positive regulation of sterol regulatory element binding protein cleavage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901310 activation of SREBP cleavage|up regulation of sterol regulatory element binding protein cleavage|positive regulation of SREBP cleavage|up regulation of SREBP cleavage|upregulation of sterol regulatory element binding protein cleavage|upregulation of SREBP cleavage|up-regulation of sterol regulatory element binding protein cleavage|activation of sterol regulatory element binding protein cleavage|up-regulation of SREBP cleavage Any process that activates or increases the frequency, rate or extent of sterol regulatory element binding protein cleavage. GO:1901311 obsolete regulation of gene expression involved in extracellular matrix organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901311 regulation of extracellular matrix protein production|regulation of expression of extracellular matrix proteins OBSOLETE. Any process that modulates the frequency, rate or extent of gene expression involved in extracellular matrix organization. CHEBI:85057 2-methylhexadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85057 CHEBI:85058 12-methyloctadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85058 CHEBI:85059 3-methylundecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85059 GO:0061530 aspartate secretion, neurotransmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061530 The regulated release of aspartate by a cell in which the aspartate acts as a neurotransmitter. GO:0061531 primary amine secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061531 The regulated release of a primary amine by a cell. GO:0061532 primary amine secretion, neurotransmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061532 The regulated release of a primary amine by a cell, in which the primary amine acts as a neurotransmitter. GO:0061533 norepinephrine secretion, neurotransmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061533 noradrenaline secretion, neurotransmission The regulated release of norepinephrine by a cell, in which the norepinephrine acts as a neurotransmitter. GO:0061534 gamma-aminobutyric acid secretion, neurotransmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061534 The regulated release of gamma-aminobutyric acid by a cell, in which the gamma-aminobutyric acid acts as a neurotransmitter. GO:0061535 glutamate secretion, neurotransmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061535 The controlled release of glutamate by a cell, in which the glutamate acts as a neurotransmitter. GO:0061536 glycine secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061536 The controlled release of glycine by a cell. GO:0061537 glycine secretion, neurotransmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061537 The controlled release of glycine by a cell, in which glycine acts as a neurotransmitter. GO:0061538 histamine secretion, neurotransmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061538 The controlled release of histamine by a cell, in which the histamine acts as a neurotransmitter. GO:0061539 octopamine secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061539 The controlled release of octopamine by a cell. CHEBI:51625 indolinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51625 CHEBI:26666 short-chain fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26666 CHEBI:26667 sialic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26667 CHEBI:26660 sesterterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26660 CHEBI:75603 EC 6.* (ligase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75603 CHEBI:51614 diarylmethane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51614 CHEBI:75600 EC 6.3.* (C-N bond-forming ligase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75600 CHEBI:75606 hydroxamic acid ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75606 CHEBI:26675 silicic acid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_26675 CHEBI:26677 silicon molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26677 CHEBI:75604 EC 6.4.* (C-C bond-forming ligase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75604 CHEBI:26672 siderophore biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26672 CHEBI:26673 organosilanediol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26673 CHEBI:75608 2-palmitoyloxypalmityl palmitate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75608 CHEBI:75609 1-alpha-linolenoyl-2-oleoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75609 UBERON:0013636 epithelium of intestinal villus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013636 villus epithelium|villous epithelium|intestinal villus epithelium A epithelium that is part of a intestinal villus. UBERON:0013637 prostate gland lateral lobe biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013637 lateral lobe of prostate gland|lateral prostate|lateral ventral lobe of prostate gland|lateral lobe of prostate The prostate gland lobe that is located on the lateral side of the organ. CHEBI:75614 1-linoleoyl-2-oleoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75614 CHEBI:75611 1-arachidonoyl-2-oleoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75611 CHEBI:75612 1-arachidonoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75612 CHEBI:26649 serine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26649 CHEBI:26642 selenous acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26642 CHEBI:75617 N(3')-acetylgentamycin C(4+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75617 CHEBI:26643 aldehydic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26643 CHEBI:75615 (8E,10S,12Z,15Z)-10-hydroperoxyoctadeca-8,12,15-trienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75615 CHEBI:26645 semiochemical biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26645 CHEBI:75616 gentamicin C(5+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75616 UBERON:0013631 sesamoid element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013631 sesamoid Ossicle that develops within bands of dense, regular connective tissue (e.g., tendons and ligaments). Sesamoids are generally located proximate to a bony prominence, over which the dense regular connective tissue wraps, and/or a joint or articulation. UBERON:0013632 sesamoid cartilage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013632 cartilago sesamoidea|sesamoid cartilage of cricopharyngeal ligament A sesamoid element that is composed primarily of cartilage tissue. CHEBI:26640 selenomethionines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26640 UBERON:0013630 short bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013630 Short bones are designated as those bones that are as wide as they are long. Their primary function is to provide support and stability with little to no movement. They are one of five types of bones: long, short, flat, irregular and sesamoid. Examples of these bones include the tarsals in the foot and the carpals in the hand. CHEBI:75610 1-alpha-linolenoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75610 CHEBI:75624 palmitoleyl oleate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75624 CHEBI:75625 stearyl oleate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75625 CHEBI:26658 sesquiterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26658 CHEBI:75622 palmityl oleate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75622 CHEBI:75623 palmitoleyl alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75623 CHEBI:75628 arachidyl oleate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75628 CHEBI:75629 palmityl palmitoleate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75629 CHEBI:75626 oleyl oleate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75626 CHEBI:75627 icosan-1-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75627 CHEBI:26650 serine family amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26650 CHEBI:75620 decyl oleate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75620 CHEBI:75635 mesaconyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75635 CHEBI:75636 3-methylfumaryl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75636 CHEBI:75634 L-erythro-3-methylmalyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75634 CHEBI:75637 (3R)-citramalyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75637 UBERON:0013697 exocrine pancreas epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013697 epithelium of exocrine pancreas|exocrine pancreas epithelial cell Epithelium lining the exocrine pancreas. UBERON:0013699 strand of axillary hair biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013699 axillary hair|hair of axilla|axilla hair A strand of hair that is part of a axilla. UBERON:0013694 brain endothelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013694 cerebromicrovascular endothelium Vascular endothelium found in blood vessels of the blood-brain-barrier. UBERON:0013695 colon endothelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013695 colorectal endothelium|colonic endothelium|colonic endothelial cell|colorectal endothelial cell|colon endothelial cell|colon endothelial cells Vascular endothelium found in colon blood vessels. CHEBI:26628 selenium molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26628 CHEBI:75631 palmityl stearate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75631 CHEBI:26629 selenoamino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26629 CHEBI:75646 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1'-sn-glycerol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75646 CHEBI:75645 1-acyl-2-palmitoyl-sn-glycero-3-phospho-(1'-sn-glycerol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75645 CHEBI:26632 selenocysteines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26632 CHEBI:75649 5-(2-methoxy-2-oxoethyl)uridine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75649 CHEBI:26634 selenodiglutathione biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26634 UBERON:0013686 anatomical conduit space biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013686 foramen space An anatomical space which is the lumen of some anatomical conduit and connects two or more spaces together[FMA,modified]. CHEBI:26630 selenocystathionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26630 CHEBI:61001 2-O-(6-phosphono-alpha-D-mannosyl)-D-glyceric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61001 UBERON:0013683 left dorsal thalamus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013683 left thalamus A dorsal thalamus that is in_the_left_side_of a diencephalon. UBERON:0013684 right dorsal thalamus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013684 right thalamus A dorsal thalamus that is in_the_right_side_of a diencephalon. UBERON:0013685 foramen of skull biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013685 cranial foramen|cranial conduit|foramina of the skull|foramen of skull Anatomical space that is an opening in a bone of the skull. CHEBI:61006 mannosyl diphosphorylinositol ceramide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61006 CHEBI:61007 amino fatty acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61007 CHEBI:61008 nitrogen-containing fatty acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61008 CHEBI:75657 5-(carboxymethyl)uridine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75657 CHEBI:75658 5-(carboxymethyl)uridine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75658 CHEBI:26604 santonin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26604 CHEBI:26605 saponin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26605 CHEBI:75659 O-acyl-L-carnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75659 CHEBI:26600 salutaridinol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26600 CHEBI:61011 all-trans-decaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61011 CHEBI:61016 angiotensin receptor antagonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61016 CHEBI:61015 nephrotoxin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61015 GO:0061700 GATOR2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061700 A multiprotein subcomplex of GATOR that regulates mTOR signaling by interacting with the Rag GTPases. In humans this complex consists of Mios, WDR24, WDR59, Seh1L, Sec13. GO:0061701 bacterial outer membrane vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061701 A spherical, bilayered proteolipid vesicle released from gram-negative bacterial outer membranes. GO:0061702 inflammasome complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061702 A cytosolic protein complex that is capable of activating caspase-1. GO:0061703 pyroptosome complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061703 ASC pyroptosome A protein complex that consists of an assemble of ASC dimers that is capable of inducing pyroptosis. GO:0061704 glycolytic process from sucrose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061704 The chemical reactions and pathways resulting in the breakdown of a sucrose into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules. CHEBI:75650 5-(2-methoxy-2-oxoethyl)uridine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75650 GO:0061705 sucrose catabolic process to fructose-6-phosphate through glucose and fructose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061705 MetaCyc:PWY-621 The chemical reactions and pathways resulting in the breakdown of sucrose, to yield fructose-6-phosphate through both glucose and fructose intermediates. GO:0061706 glycolytic process from sucrose through glucose and fructose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061706 MetaCyc:PWY-1042 The chemical reactions and pathways resulting in the breakdown of sucrose into pyruvate through both glucose and fructose intermediates, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules. GO:0061707 extracellular exosome macropinocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061707 The single-organism macropinocytosis process that results in the uptake of an extracellular exosome. CHEBI:26606 sapogenin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26606 GO:0061708 tRNA-5-taurinomethyluridine 2-sulfurtransferase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061708 Reactome:R-HSA-6787447|RHEA:47040|MetaCyc:RXN-16821 Catalysis of 5-taurinomethyluridine in tRNA + a [protein]-S-sulfanylcysteine + ATP + a reduced electron acceptor = a 5-taurinomethyl-2-thiouridine in tRNA + a [protein]-L-cysteine + AMP + an oxidized electron acceptor + diphosphate + H+. CHEBI:26607 saturated fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26607 GO:0061709 reticulophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061709 endoplasmic reticulum autophagy|ER-phagy|ER autophagy|autophagy of the ER|endoplasmic reticulum degradation|ER degradation|autophagy of the endoplasmic reticulum The selective autohagy process in which parts of the endoplasmic reticulum are loaded into autophagosomes, delivered to the vacuole, and degraded in response to changing cellular conditions. NCBITaxon:58022 Gnetophyta organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_58022 CHEBI:26613 scyllo-inositol phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26613 NCBITaxon:58023 Tracheophyta organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_58023 vascular plants|vascular plants NCBITaxon:58024 Spermatophyta organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_58024 seed plants|seed plants CHEBI:26616 seco-androstane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26616 CHEBI:61027 (2E,4E)-6-(2-aminophenyl)-2-hydroxy-6-oxohexa-2,4-dienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61027 CHEBI:75665 (2S,3R)-capreomycidine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75665 GO:0071087 alpha11-beta1 integrin-collagen type I complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071087 ITGA11-ITGB1-COL1A1 complex A protein complex that consists of an alpha11-beta1 integrin complex bound to a type I collagen. GO:0071088 alpha5-beta1 integrin-tissue transglutaminase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071088 ITGA5-ITGB1-TGM2 complex A protein complex that consists of an alpha5-beta1 integrin complex bound to tissue transglutaminase. GO:0071085 alphaIIb-beta3 integrin-CD9 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071085 ITGA2b-ITGB3-CD9 complex A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface protein CD9. GO:0071086 alphaIIb-beta3 integrin-CD9-CD47-platelet glycoprotein Ib complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071086 ITGA2b-ITGB3-CD9-GP1b-CD47 complex A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface proteins CD9 and CD47, and the heterodimeric platelet glycoprotein Ib. GO:0071083 alphaV-beta3 integrin-CD47-FCER2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071083 ITGAV-ITGB3-CD447-FCER2 complex A protein complex that consists of an alphaV-beta3 integrin complex bound to the cell surface protein CD47 and the low-affinity immunoglobulin epsilon Fc receptor (FCER2). GO:0071084 alpha2-beta1 integrin-CD47 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071084 ITGA2-ITGB1-CD47 complex A protein complex that consists of an alpha2-beta1 integrin complex bound to the cell surface protein CD47. GO:0071081 alpha3-beta1 integrin-CD63 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071081 ITGA3-ITGB1-CD63 complex A protein complex that consists of an alpha3-beta1 integrin complex bound to the tetraspanin CD63. GO:0071082 alpha9-beta1 integrin-tenascin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071082 ITGA9-ITGB1-TNC complex A protein complex that consists of an alpha9-beta1 integrin complex bound to the extracellular matrix protein tenascin. GO:0071080 alpha3-beta1 integrin-basigin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071080 ITGA3-ITGB1-BSG complex A protein complex that consists of an alpha3-beta1 integrin complex bound to the cell surface protein basigin. GO:1901288 iron-sulfur-molybdenum cofactor biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901288 iron-sulfur-molybdenum cofactor formation|FeMo-co formation|iron-molybdenum cofactor biosynthetic process|iron-molybdenum cofactor biosynthesis|iron-molybdenum cofactor anabolism|iron-molybdenum cofactor synthesis|iron-molybdenum cofactor formation|FeMo-co biosynthetic process|FeMo-co biosynthesis|iron-sulfur-molybdenum cofactor anabolism|iron-sulfur-molybdenum cofactor biosynthesis|FeMo-co anabolism|iron-sulfur-molybdenum cofactor synthesis|FeMo-co synthesis The chemical reactions and pathways resulting in the formation of iron-sulfur-molybdenum cofactor. GO:1901289 succinyl-CoA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901289 succinyl-CoA degradation|succinyl-CoA breakdown|succinyl-CoA catabolism The chemical reactions and pathways resulting in the breakdown of succinyl-CoA. GO:1901286 iron-sulfur-molybdenum cofactor metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901286 iron-molybdenum cofactor metabolic process|iron-molybdenum cofactor metabolism|FeMo-co metabolic process|FeMo-co metabolism|iron-sulfur-molybdenum cofactor metabolism The chemical reactions and pathways involving iron-sulfur-molybdenum cofactor. GO:1901287 iron-sulfur-molybdenum cofactor catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901287 iron-sulfur-molybdenum cofactor degradation|FeMo-co degradation|iron-molybdenum degradation|iron-sulfur-molybdenum cofactor breakdown|FeMo-co breakdown|iron-molybdenum catabolism|iron-molybdenum breakdown|FeMo-co catabolism|FeMo-co catabolic process|iron-molybdenum catabolic process|iron-sulfur-molybdenum cofactor catabolism The chemical reactions and pathways resulting in the breakdown of iron-sulfur-molybdenum cofactor. GO:1901295 regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901295 regulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|regulation of canonical Wnt-activated signaling pathway involved in cardiac muscle cell fate commitment|regulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment Any process that modulates the frequency, rate or extent of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment. GO:1901296 negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901296 downregulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|negative regulation of canonical Wnt-activated signaling pathway involved in cardiac muscle cell fate commitment|down regulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|negative regulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|down-regulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|inhibition of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|negative regulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|inhibition of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|down-regulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|down regulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|downregulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment Any process that stops, prevents or reduces the frequency, rate or extent of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment. GO:1901293 nucleoside phosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901293 nucleoside phosphate anabolism|nucleoside phosphate synthesis|nucleoside phosphate formation|nucleoside phosphate biosynthesis The chemical reactions and pathways resulting in the formation of a nucleoside phosphate. GO:1901294 obsolete negative regulation of SREBP signaling pathway by negative regulation of DNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901294 negative regulation of SREBP-mediated signalling pathway by down regulation of DNA binding|negative regulation of SREBP signaling pathway by inhibition of DNA binding|negative regulation of SREBP-mediated signaling pathway by downregulation of DNA binding|negative regulation of SREBP-mediated signaling pathway by down-regulation of DNA binding|negative regulation of SREBP-mediated signaling pathway by negative regulation of DNA binding|negative regulation of SREBP signaling pathway by down regulation of DNA binding|negative regulation of SREBP-mediated signalling pathway by inhibition of DNA binding|inhibition of SREBP-dependent transcription by blocking DNA binding|negative regulation of SREBP-mediated signalling pathway by down-regulation of DNA binding|negative regulation of SREBP-mediated signalling pathway by negative regulation of DNA binding|negative regulation of SREBP-mediated signaling pathway by inhibition of DNA binding|negative regulation of SREBP signaling pathway by downregulation of DNA binding|negative regulation of SREBP signaling pathway by down-regulation of DNA binding|negative regulation of SREBP-mediated signaling pathway by down regulation of DNA binding|negative regulation of SREBP-mediated signalling pathway by downregulation of DNA binding OBSOLETE. Negative regulation of DNA binding that results in negative regulation of a SREBP signaling pathway. GO:1901291 negative regulation of double-strand break repair via single-strand annealing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901291 downregulation of double-strand break repair via single-strand annealing|down regulation of double-strand break repair via single-strand annealing|inhibition of double-strand break repair via single-strand annealing|down-regulation of double-strand break repair via single-strand annealing Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via single-strand annealing. GO:1901292 nucleoside phosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901292 nucleoside phosphate degradation|nucleoside phosphate breakdown|nucleoside phosphate catabolism The chemical reactions and pathways resulting in the breakdown of a nucleoside phosphate. GO:1901290 succinyl-CoA biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901290 succinyl-CoA formation|succinyl-CoA biosynthesis|succinyl-CoA anabolism|succinyl-CoA synthesis The chemical reactions and pathways resulting in the formation of succinyl-CoA. CHEBI:36063 oxytocic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36063 CHEBI:36064 taxane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36064 CHEBI:36061 octa-2,4-dienoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36061 CHEBI:36062 3,4-dihydroxybenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36062 GO:0071089 alphaV-beta3 integrin-tissue transglutaminase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071089 ITGAV-ITGB3-TGM2 complex A protein complex that consists of an alphaV-beta3 integrin complex bound to tissue transglutaminase. CHEBI:36066 prostaglandins Falpha biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36066 GO:0071076 RNA 3' uridylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071076 The enzymatic addition of a sequence of uridylyl residues at the 3' end of an RNA molecule. GO:0071077 adenosine 3',5'-bisphosphate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071077 adenosine 3',5'-diphosphate transporter activity|adenosine 3'-phosphate-5'-phosphate transmembrane transporter activity Enables the transfer of adenosine 3',5'-bisphosphate from one side of a membrane to the other. GO:0071074 eukaryotic initiation factor eIF2 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071074 Interacting selectively and non-covalently with eukaryotic initiation factor eIF2, a protein complex involved in the initiation of ribosome-mediated translation. CHEBI:145951 4-hydroxymethylsteroid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_145951 GO:0071075 CUGBP1-eIF2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071075 A protein complex that contains the eukaryotic translation initiation factor 2 complex (EIF2), CUG binding protein 1, and several endoplasmic reticulum proteins; the complex is involved in the regulation of translation. GO:0071072 negative regulation of phospholipid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071072 negative regulation of phospholipid biosynthesis|inhibition of phospholipid biosynthetic process|negative regulation of phospholipid anabolism|down regulation of phospholipid biosynthetic process|negative regulation of phospholipid synthesis|downregulation of phospholipid biosynthetic process|negative regulation of phospholipid formation|down-regulation of phospholipid biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids. CHEBI:145952 4-formyl steroid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_145952 GO:0071073 positive regulation of phospholipid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071073 up-regulation of phospholipid biosynthetic process|upregulation of phospholipid biosynthetic process|positive regulation of phospholipid anabolism|up regulation of phospholipid biosynthetic process|positive regulation of phospholipid synthesis|activation of phospholipid biosynthetic process|positive regulation of phospholipid biosynthesis|positive regulation of phospholipid formation|stimulation of phospholipid biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids. GO:0071070 alpha4-beta1 integrin-thrombospondin-2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071070 ITGA4-ITGB1-THBS2 complex A protein complex that consists of an alpha4-beta1 integrin complex bound to thrombospondin-2. CHEBI:145954 4alpha-formyl steroid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_145954 GO:0071071 regulation of phospholipid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071071 regulation of phospholipid synthesis|regulation of phospholipid formation|regulation of phospholipid biosynthesis|regulation of phospholipid anabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids. CHEBI:36080 protein biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36080 GO:1901299 negative regulation of hydrogen peroxide-mediated programmed cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901299 down regulation of hydrogen peroxide-mediated programmed cell death|inhibition of hydrogen peroxide-mediated programmed cell death|down-regulation of hydrogen peroxide-mediated programmed cell death|downregulation of hydrogen peroxide-mediated programmed cell death Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide-mediated programmed cell death. GO:1901297 positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901297 positive regulation of canonical Wnt-activated signaling pathway involved in cardiac muscle cell fate commitment|up regulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|positive regulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|activation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|upregulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|up-regulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|positive regulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|up-regulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|activation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|upregulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|up regulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment Any process that activates or increases the frequency, rate or extent of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment. GO:1901298 regulation of hydrogen peroxide-mediated programmed cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901298 Any process that modulates the frequency, rate or extent of hydrogen peroxide-mediated programmed cell death. CHEBI:36078 cholanoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36078 GO:0071078 fibronectin-tissue transglutaminase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071078 FN-TGM2 complex A protein complex that consists of fibronectin bound to tissue transglutaminase, and is involved in cell adhesion. GO:0071079 alpha2-beta1 integrin-chondroadherin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071079 ITGA2-ITGB1-CHAD complex A protein complex that consists of an alpha2-beta1 integrin complex bound to the cartilage matrix protein chondroadherin. CHEBI:145942 4alpha-formyl-5alpha-cholest-7-en-3beta-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_145942 CHEBI:145943 4alpha-carboxy-5alpha-cholest-7-en-3beta-ol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_145943 CHEBI:51688 enal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_51688 CHEBI:51689 enone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_51689 CHEBI:36047 antibacterial drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36047 CHEBI:145945 4beta-hydroxymethyl steroid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_145945 CHEBI:36042 icosa-5,9,11,14-tetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36042 CHEBI:145946 N-acetyl-D-leucinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_145946 CHEBI:51683 methoxybenzenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51683 CHEBI:36040 icosa-6,8,11,14-tetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36040 CHEBI:36045 icosa-6,8,10,14-tetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36045 CHEBI:36046 icosatetraenedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36046 CHEBI:36043 antimicrobial drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36043 CHEBI:36044 antiviral drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36044 CHEBI:51681 dimethoxybenzene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51681 GO:0071098 alpha6-beta4 integrin-Fyn complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071098 ITGA6-ITGB4-FYN complex A protein complex that consists of an alpha6-beta4 integrin complex bound to the Src family tyrosine kinase Fyn. GO:0071099 alphaV-beta6 integrin-TGFbeta-3 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071099 ITGAV-ITGB6-TFGB3 complex A protein complex that consists of an alphaV-beta6 integrin complex bound to transforming growth factor beta-3 (TGFbeta-3). GO:0071096 alphaV-beta3 integrin-gelsolin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071096 ITGAV-ITGB3-Gsn complex A protein complex that consists of an alphaV-beta3 integrin complex bound to gelsolin. GO:0071097 alphaV-beta3 integrin-paxillin-Pyk2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071097 ITGAV-ITGB3-PXN-PTK2b complex A protein complex that consists of an alphaV-beta3 integrin complex bound to paxillin and the FAK-related kinase Pyk2. GO:0071094 alpha6-beta4 integrin-CD9 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071094 ITGA6-ITGB4-CD9 complex A protein complex that consists of an alpha6-beta4 integrin complex bound to the cell surface protein CD9. GO:0071095 alpha3-beta1 integrin-thrombospondin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071095 ITGA3-ITGB1-THBS1 complex A protein complex that consists of an alpha3-beta1 integrin complex bound to thrombospondin. GO:0071092 alpha3-beta1 integrin-tissue transglutaminase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071092 ITGA3-ITGB1-TGM2 complex A protein complex that consists of an alpha3-beta1 integrin complex bound to tissue transglutaminase. CHEBI:145932 (S)-2-methylbutanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_145932 GO:0071093 alpha5-beta1 integrin-fibronectin-tissue transglutaminase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071093 ITGA5-ITGB1-FN1-TGM2 complex A protein complex that consists of an alpha5-beta1 integrin complex bound to fibronectin and tissue transglutaminase. GO:0071090 alphaIIb-beta3 integrin-fibronectin-tissue transglutaminase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071090 ITGA2b-ITGB3-FN1-TGM2 complex A protein complex that consists of an alphaIIb-beta3 integrin complex bound to fibronectin and tissue transglutaminase. GO:0071091 alpha1-beta1 integrin-tissue transglutaminase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071091 ITGA1-ITGB1-TGM2 complex A protein complex that consists of an alpha1-beta1 integrin complex bound to tissue transglutaminase. CHEBI:36059 hydroxy monocarboxylic acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36059 CHEBI:36056 furancarboxylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36056 CHEBI:36054 benzoate ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36054 CHEBI:36055 furoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36055 CHEBI:36027 stilbenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36027 CHEBI:36025 octadeca-9,11-dienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36025 CHEBI:36029 butenoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36029 UBERON:0013605 layer of lateral geniculate body biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013605 CHEBI:36023 vaccenic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36023 CHEBI:36024 trideca-2,6-dienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36024 CHEBI:36021 octadec-9-enoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36021 CHEBI:36022 octadec-6-enoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36022 CHEBI:36038 icosa-7,9,11,14-tetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36038 CHEBI:36039 icosa-5,8,10,14-tetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36039 CHEBI:36036 fatty acid 20:3 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36036 CHEBI:36037 (5Z,9E,14Z)-icosa-5,9,14-trienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36037 CHEBI:36030 pentenoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36030 CHEBI:106304 sphingomyelin d18:1/16:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_106304 CHEBI:36031 docosenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36031 CHEBI:51652 dithianes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51652 CHEBI:36035 icosa-5,8,11,13-tetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36035 CHEBI:36032 tetracosenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36032 CHEBI:36033 icosatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36033 CHEBI:12040 4-oxohex-2-enedioate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_12040 CHEBI:26689 singlet dioxygen biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_26689 CHEBI:36005 docosahexaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36005 CHEBI:36006 icosapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36006 CHEBI:36003 decenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36003 CHEBI:36004 tetradecenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36004 CHEBI:36009 omega-6 fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36009 CHEBI:36007 trans-stilbene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36007 CHEBI:145902 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_145902 CHEBI:12071 5,10-methylenetetrahydrofolate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_12071 CHEBI:36016 chloroethanes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36016 CHEBI:36014 chloromethane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36014 CHEBI:12060 5'-deoxy-5'-fluoroadenosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_12060 CHEBI:36011 pinosylvin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36011 GO:0046043 TDP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046043 TDP metabolism The chemical reactions and pathways involving TDP, ribosylthymine diphosphate. GO:0071000 response to magnetism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071000 response to magnetic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnetic stimulus. GO:0046044 TMP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046044 TMP metabolism The chemical reactions and pathways involving TMP, ribosylthymine monophosphate. GO:0046041 ITP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046041 ITP metabolism The chemical reactions and pathways involving ITP, inosine triphosphate. GO:0046042 ITP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046042 ITP biosynthesis|ITP anabolism|ITP synthesis|ITP formation The chemical reactions and pathways resulting in the formation of ITP, inosine triphosphate. GO:1901208 negative regulation of heart looping biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901208 down regulation of heart looping|inhibition of cardiac looping|downregulation of heart looping|down regulation of cardiac looping|down-regulation of heart looping|downregulation of cardiac looping|inhibition of heart looping|down-regulation of cardiac looping|negative regulation of cardiac looping Any process that stops, prevents or reduces the frequency, rate or extent of heart looping. GO:1901209 positive regulation of heart looping biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901209 activation of cardiac looping|upregulation of heart looping|up-regulation of cardiac looping|up regulation of heart looping|upregulation of cardiac looping|activation of heart looping|up regulation of cardiac looping|up-regulation of heart looping|positive regulation of cardiac looping Any process that activates or increases the frequency, rate or extent of heart looping. GO:0046040 IMP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046040 IMP metabolism The chemical reactions and pathways involving IMP, inosine monophosphate. GO:1901206 obsolete positive regulation of adrenergic receptor signaling pathway involved in heart process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901206 up-regulation of beta-adrenergic receptor signalling pathway involved in heart process|positive regulation of adrenergic receptor signalling pathway involved in heart process|up regulation of adrenergic receptor signalling pathway involved in heart process|up-regulation of adrenergic receptor signaling pathway involved in heart process|upregulation of beta-adrenergic receptor signalling pathway involved in heart process|upregulation of adrenergic receptor signalling pathway involved in heart process|upregulation of adrenergic receptor signaling pathway involved in heart process|up regulation of beta-adrenergic receptor signalling pathway involved in heart process|positive regulation of beta-adrenergic receptor signalling pathway involved in heart process|up-regulation of adrenergic receptor signalling pathway involved in heart process|up regulation of adrenergic receptor signaling pathway involved in heart process|activation of beta-adrenergic receptor signalling pathway involved in heart process|activation of adrenergic receptor signaling pathway involved in heart process|activation of adrenergic receptor signalling pathway involved in heart process OBSOLETE. Any process that activates or increases the frequency, rate or extent of a cardiac adrenergic receptor signaling pathway. GO:1901207 regulation of heart looping biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901207 regulation of cardiac looping Any process that modulates the frequency, rate or extent of heart looping. GO:1901204 obsolete regulation of adrenergic receptor signaling pathway involved in heart process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901204 regulation of adrenergic receptor signalling pathway involved in heart process|regulation of beta-adrenergic receptor signalling pathway involved in heart process OBSOLETE. Any process that modulates the frequency, rate or extent of a cardiac adrenergic receptor signaling pathway. GO:1901205 obsolete negative regulation of adrenergic receptor signaling pathway involved in heart process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901205 inhibition of beta-adrenergic receptor signalling pathway involved in heart process|inhibition of adrenergic receptor signaling pathway involved in heart process|downregulation of adrenergic receptor signalling pathway involved in heart process|down regulation of adrenergic receptor signalling pathway involved in heart process|down regulation of beta-adrenergic receptor signalling pathway involved in heart process|downregulation of beta-adrenergic receptor signalling pathway involved in heart process|down regulation of adrenergic receptor signaling pathway involved in heart process|inhibition of adrenergic receptor signalling pathway involved in heart process|downregulation of adrenergic receptor signaling pathway involved in heart process|down-regulation of beta-adrenergic receptor signalling pathway involved in heart process|negative regulation of beta-adrenergic receptor signalling pathway involved in heart process|down-regulation of adrenergic receptor signaling pathway involved in heart process|down-regulation of adrenergic receptor signalling pathway involved in heart process|negative regulation of adrenergic receptor signalling pathway involved in heart process OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of a cardiac adrenergic receptor signaling pathway. GO:1901202 negative regulation of extracellular matrix assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901202 down regulation of extracellular matrix assembly|downregulation of extracellular matrix assembly|down-regulation of extracellular matrix assembly|inhibition of extracellular matrix assembly Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix assembly. GO:0046049 UMP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046049 UMP metabolism The chemical reactions and pathways involving UMP, uridine monophosphate. GO:1901203 positive regulation of extracellular matrix assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901203 upregulation of extracellular matrix assembly|up regulation of extracellular matrix assembly|activation of extracellular matrix assembly|up-regulation of extracellular matrix assembly Any process that activates or increases the frequency, rate or extent of extracellular matrix assembly. GO:0046047 TTP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046047 TTP catabolism|TTP degradation|TTP breakdown|TTP hydrolysis The chemical reactions and pathways resulting in the breakdown of TTP, ribosylthymine triphosphate. GO:0061680 Entner-Doudoroff pathway through gluconate to D-glyceraldehyde biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061680 MetaCyc:ENTNER-DOUDOROFF-PWY-II The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate and yields pyruvate and D-glyceraldehyde. GO:1901200 negative regulation of calcium ion transport into cytosol involved in cellular response to salt stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901200 negative regulation of calcium ion transport into cytosol involved in cellular response to ionic osmotic stress|negative regulation of calcium ion transport into cytosol involved in cellular salinity response Any negative regulation of calcium ion transport into cytosol that is involved in cellular response to salt stress. GO:0061681 Entner-Doudoroff pathway through gluconate to D-glyceraldehyde-3-phosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061681 MetaCyc:ENTNER-DOUDOROFF-PWY-III The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate and yields pyruvate and D-glyceraldehyde-3-phosphate. GO:1901201 regulation of extracellular matrix assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901201 Any process that modulates the frequency, rate or extent of extracellular matrix assembly. GO:0046048 UDP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046048 UDP metabolism The chemical reactions and pathways involving UDP, uridine (5'-)diphosphate. GO:0046045 TMP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046045 TMP degradation|TMP breakdown|TMP catabolism The chemical reactions and pathways resulting in the breakdown of TMP, ribosylthymine monophosphate. GO:0061682 seminal vesicle morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061682 The process in which the anatomical structures of a seminal vesicle are generated and organized. GO:0061683 branching involved in seminal vesicle morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061683 seminal vesicle branching morphogenesis|seminal vesicle branching|seminal gland branching morphogenesis|gonecyst branching morphogenesis The process in which the branching structure of the seminal vesicle is generated and organized. A branch is a division or offshoot from a main stem. GO:0046046 TTP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046046 TTP metabolism The chemical reactions and pathways involving TTP, ribosylthymine triphosphate. GO:0061684 chaperone-mediated autophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061684 Wikipedia:Chaperone-mediated_autophagy CMA|CASA|chaperone-assisted selective autophagy The autophagy process which begins when chaperones and co-chaperones recognize a target motif and unfold the substrate protein. The proteins are then transported to the lysosome where they are degraded. GO:0061685 diphthine methylesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061685 RHEA:42656|EC:3.1.1.97 Catalysis of the reaction: diphthine methyl ester + H2O <=> diphthine + H+ + methanol. GO:0061686 hercynylcysteine sulfoxide synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061686 EC:1.14.99.51|RHEA:42704 hercynylcysteine S-oxide synthase|hercynylcysteine sulfoxide synthase Catalysis of the reaction: L-cysteine + N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (hercynine) + O2 <=> hercynylcysteine sulfoxide + H2O. GO:0061687 detoxification of inorganic compound biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061687 Any process that reduces or removes the toxicity of inorganic compounds. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of inorganic compounds. GO:0061688 glycolytic process via Entner-Doudoroff Pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061688 gluconate pathway A glycolytic process in which the glucose is catabolized to pyruvate by first entering the Entner-Doudoroff pathway to yield pyruvate and glyceraldehyde-3-phosphate. The glyceraldehyde-3-phosphate is subsequently converted to pyruvate by the core glycolytic enzymes. GO:0061689 tricellular tight junction biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061689 An specialized occluding junction where three epithelial cells meet. It is composed of a branching network of sealing strands that run perpendicularly to the bicellular tight junction at the point of contact between three epithelial cells in an epithelial sheet. GO:0071009 U4atac/U6atac x U5 tri-snRNP complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071009 U4atac/U6atac.U5 snRNP complex A spliceosomal snRNP complex that is formed by the association of the U4atac/U6atac and U5 snRNPs. GO:0071007 U2-type catalytic step 2 spliceosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071007 GT-AG catalytic step 2 spliceosome|yeast U2-type spliceosomal complex A2-2|mammalian U2-type spliceosomal complex C1|major catalytic step 2 spliceosome|mammalian U2-type spliceosomal complex C A spliceosomal complex that contains the U2, U5 and U6 snRNPs bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the U2, U5 and U6 snRNPs. GO:0071008 U2-type post-mRNA release spliceosomal complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071008 major post-mRNA release spliceosomal complex|GT-AG post-mRNA release spliceosomal complex|U2/U5/U6 tri-snRNP complex|mammalian U2-type spliceosomal complex I|U2/U5/U6 snRNP complex A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and the U2, U5 and U6 snRNPs. GO:0071005 U2-type precatalytic spliceosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071005 yeast U12-type spliceosomal complex A2-1|major precatalytic spliceosome|mammalian U2-type spliceosomal complex B1|GT-AG precatalytic spliceosome|mammalian U2-type spliceosomal complex B A spliceosomal complex that is formed by the recruitment of the preassembled U4/U6.U5 tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the U1, U2 and U4/U6.U5 snRNPs. GO:0071006 U2-type catalytic step 1 spliceosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071006 GT-AG catalytic step 1 spliceosome|mammalian U2-type spliceosomal complex B*|U2-type activated spliceosome|mammalian U2-type spliceosomal complex B2|yeast U2-type spliceosomal complex A1|major catalytic step 1 spliceosome A spliceosomal complex that is formed by the displacement of the U1 and U4 snRNPs from the precatalytic spliceosome; the U2, U5 and U6 snRNPs remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the U2, and U5 and U6 snRNPs. GO:0071003 penta-snRNP complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071003 penta-RNP complex A ribonucleoprotein complex that is formed by the association of the U1, U2, U4/U6 and U5 small nuclear ribonucleoproteins. GO:0071004 U2-type prespliceosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071004 major prespliceosome|GT-AG prespliceosome|yeast U2-type spliceosomal complex B|mammalian U2-type spliceosomal complex A A spliceosomal complex that is formed by association of the 5' splice site with the U1 snRNP, while the branch point sequence is recognized by the U2 snRNP. The prespliceosome includes many proteins in addition to those found in the U1 and U2 snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation. CHEBI:9003 salicin 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_9003 GO:0071001 U4/U6 snRNP biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071001 A ribonucleoprotein complex that contains the extensively base paired small nuclear RNAs U4 and U6, a heptameric ring of Sm proteins associated with U4, the Lsm2-8 heptameric ring complex associated with U6, as well as several proteins that are unique to the U4 snRNP or U6 snRNPs, some of which remain associated with the U4/U6 snRNA both while the U4 snRNP is free or assembled into a series of spliceosomal complexes. GO:0071002 U4atac/U6atac snRNP biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071002 A ribonucleoprotein complex that contains the extensively base paired small nuclear RNAs U4atac and U6atac, a heptameric ring of Sm proteins associated with U4atac, the Lsm2-8 heptameric ring complex associated with U6atac, as well as several proteins that are unique to the U4atac snRNP or U6atac snRNPs, some of which remain associated with the U4atac/U6atac snRNA both while the U4atac snRNP is free or assembled into a series of spliceosomal complexes. GO:0046054 dGMP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046054 dGMP metabolism The chemical reactions and pathways involving dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate). GO:0046055 dGMP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046055 dGMP degradation|dGMP catabolism|dGMP breakdown The chemical reactions and pathways resulting in the breakdown of dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate). GO:0046052 UTP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046052 UTP degradation|UTP breakdown|UTP hydrolysis|UTP catabolism The chemical reactions and pathways resulting in the breakdown of UTP, uridine (5'-)triphosphate. GO:0046053 dAMP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046053 dAMP metabolism The chemical reactions and pathways involving dAMP, deoxyadenosine monophosphate (2'-deoxyadenosine 5'-phosphate). GO:0046050 UMP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046050 UMP degradation|UMP breakdown|UMP catabolism The chemical reactions and pathways resulting in the breakdown of UMP, uridine monophosphate. GO:1901219 regulation of cardiac chamber morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901219 regulation of heart chamber morphogenesis Any process that modulates the frequency, rate or extent of cardiac chamber morphogenesis. GO:0046051 UTP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046051 UTP metabolism The chemical reactions and pathways involving UTP, uridine (5'-)triphosphate. GO:1901217 regulation of holin activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901217 Any process that modulates the frequency, rate or extent of holin activity. GO:1901218 negative regulation of holin activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901218 down-regulation of holin activity|downregulation of holin activity|down regulation of holin activity|antiholin activity|inhibition of holin activity|phage antiholin Any process that stops, prevents or reduces the frequency, rate or extent of holin activity. GO:1901215 negative regulation of neuron death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901215 down regulation of neuronal cell death|negative regulation of neuron cell death|down-regulation of neuron death|down-regulation of neuron cell death|downregulation of neuronal cell death|inhibition of neuron cell death|downregulation of neuron death|negative regulation of neuronal cell death|down-regulation of neuronal cell death|down regulation of neuron death|inhibition of neuron death|inhibition of neuronal cell death|down regulation of neuron cell death|downregulation of neuron cell death Any process that stops, prevents or reduces the frequency, rate or extent of neuron death. GO:1901216 positive regulation of neuron death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901216 up regulation of neuronal cell death|up regulation of neuron death|activation of neuronal cell death|up-regulation of neuron cell death|positive regulation of neuronal cell death|upregulation of neuron cell death|upregulation of neuron death|up-regulation of neuronal cell death|up-regulation of neuron death|up regulation of neuron cell death|activation of neuron death|upregulation of neuronal cell death|positive regulation of neuron cell death|activation of neuron cell death Any process that activates or increases the frequency, rate or extent of neuron death. GO:1901213 regulation of transcription from RNA polymerase II promoter involved in heart development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901213 regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|global transcription regulation from Pol II promoter involved in cardiac development|regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|regulation of global transcription from Pol II promoter involved in heart development|regulation of transcription from Pol II promoter involved in cardiac development|regulation of transcription from RNA polymerase II promoter, global involved in heart development|regulation of transcription from RNA polymerase II promoter involved in cardiac development|regulation of global transcription from Pol II promoter involved in dorsal vessel development|regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|regulation of global transcription from Pol II promoter involved in cardiac development|global transcription regulation from Pol II promoter involved in heart development|regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|regulation of transcription from Pol II promoter involved in heart development|regulation of transcription from Pol II promoter involved in dorsal vessel development|global transcription regulation from Pol II promoter involved in dorsal vessel development Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the development of the heart over time. GO:1901214 regulation of neuron death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901214 regulation of neuronal cell death|regulation of neuron cell death Any process that modulates the frequency, rate or extent of neuron death. GO:0046058 cAMP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046058 3',5' cAMP metabolic process|3',5' cAMP metabolism|cyclic AMP metabolism|adenosine 3',5'-cyclophosphate metabolism|cAMP metabolism|cAMP generating peptide activity|3',5'-cAMP metabolic process|3',5'-cAMP metabolism|adenosine 3',5'-cyclophosphate metabolic process|cyclic AMP metabolic process The chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate). GO:1901211 negative regulation of cardiac chamber formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901211 down regulation of heart chamber formation|downregulation of heart chamber formation|down regulation of cardiac chamber formation|negative regulation of heart chamber formation|down-regulation of heart chamber formation|downregulation of cardiac chamber formation|down-regulation of cardiac chamber formation|inhibition of heart chamber formation|inhibition of cardiac chamber formation Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber formation. GO:1901212 positive regulation of cardiac chamber formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901212 up-regulation of cardiac chamber formation|up regulation of heart chamber formation|upregulation of cardiac chamber formation|positive regulation of heart chamber formation|activation of heart chamber formation|up regulation of cardiac chamber formation|activation of cardiac chamber formation|up-regulation of heart chamber formation|upregulation of heart chamber formation Any process that activates or increases the frequency, rate or extent of cardiac chamber formation. GO:0046059 dAMP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046059 dAMP catabolism|dAMP degradation|dAMP breakdown The chemical reactions and pathways resulting in the breakdown of dAMP, deoxyadenosine monophosphate (2'-deoxyadenosine 5'-phosphate). GO:0061670 evoked neurotransmitter secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061670 stimulus-dependant neurotransmitter secretion Neurotransmitter secretion that occurs in the presence of the action of a secretagogue or a presynaptic action potential. GO:0061671 Cbp3p-Cbp6 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061671 A protein complex located at the mitochondrial ribosome tunnel exit that is involved in efficient translation and protein complex assembly. GO:0046056 dADP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046056 dADP metabolism The chemical reactions and pathways involving dADP, deoxyadenosine diphosphate (2'-deoxyadenosine 5'-diphosphate). GO:1901210 regulation of cardiac chamber formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901210 regulation of heart chamber formation Any process that modulates the frequency, rate or extent of cardiac chamber formation. GO:0061672 glutathione hydrolase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061672 glutamine amidotransferase II complex|gamma-glutamyltranspeptidase complex|glutathionase complex Enzyme complex that in S. cerevisiae has components Dug2/Dug3 and is able to catalyze the cleavage of glutathione into glutamate and Cys-Gly. GO:0046057 dADP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046057 dADP degradation|dADP breakdown|dADP catabolism The chemical reactions and pathways resulting in the breakdown of dADP, deoxyadenosine diphosphate (2'-deoxyadenosine 5'-diphosphate). GO:0061673 mitotic spindle astral microtubule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061673 Any of the mitotic spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell. GO:0061674 gap filling involved in double-strand break repair via nonhomologous end joining biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061674 Repair of the gaps in the DNA helix using a discontinuous template during double-strand break repair via nonhomologous end joining. GO:0061675 RBL family protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061675 rhamnose-binding lectin family protein binding Interacting selectively and non-covalently with any member of the rhamnose-binding lectin (RBL) family, a family of animal lectins that show specific binding activities to L-rhamnose or D-galactose. GO:0061676 importin-alpha family protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061676 Interacting selectively and non-covalently with any member of the importin-alpha family. GO:0061677 2-dehydro-3-deoxy-D-gluconate aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061677 EC:4.1.2.51|MetaCyc:DHDOGALDOL-RXN|RHEA:35583|MetaCyc:4.1.2.51-RXN KDG aldolase activity|2-keto-3-deoxygluconate aldolase activity Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate <=> pyruvate + D-glyceraldehyde. GO:0061678 Entner-Doudoroff pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061678 MetaCyc:Entner-Doudoroff-Pathways A cellular carbohydrate catabolic process that converts a carbohydrate to pyruvate and either glyceraldehyde or glyceraldehyde-3 phosphate by dehydration and aldol cleavage via a gluconate or 6-phosphogluconate intermediate. GO:0061679 Entner-Doudoroff pathway through gluconate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061679 gluconate pathway The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate. GO:0071021 U2-type post-spliceosomal complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071021 yeast U2-type spliceosomal complex A2-3|major post-spliceosomal complex|mammalian U2-type spliceosomal complex C2|GT-AG post-spliceosomal complex A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, U5, U2 and U6. GO:0046065 dCTP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046065 dCTP metabolism The chemical reactions and pathways involving dCTP, deoxycytidine triphosphate. GO:0046066 dGDP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046066 dGDP metabolism The chemical reactions and pathways involving dGDP, deoxyguanosine diphosphate, (2'-deoxyguanosine 5'-diphosphate). GO:0071022 U12-type post-spliceosomal complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071022 AT-AC post-spliceosomal complex|yeast U12-type spliceosomal complex A2-3|minor post-spliceosomal complex|mammalian U12-type spliceosomal complex C2 A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, U5, U12 and U6atac. GO:0046063 dCMP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046063 dCMP metabolism The chemical reactions and pathways involving dCMP, deoxycytidine monophosphate. GO:0046064 dCMP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046064 dCMP anabolism|dCMP synthesis|dCMP formation|dCMP biosynthesis The chemical reactions and pathways resulting in the formation of dCMP, deoxycytidine monophosphate. GO:0071020 post-spliceosomal complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071020 yeast spliceosomal complex A2-3|mammalian spliceosomal complex C2 A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, including U5. GO:0046061 dATP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046061 dATP degradation|dATP breakdown|dATP catabolism The chemical reactions and pathways resulting in the breakdown of dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate). GO:0046062 dCDP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046062 dCDP metabolism The chemical reactions and pathways involving dCDP, deoxycytidine 5'-diphosphate. GO:1901228 positive regulation of transcription from RNA polymerase II promoter involved in heart development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901228 activation of global transcription from RNA polymerase II promoter involved in heart development|stimulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|up-regulation of global transcription from RNA polymerase II promoter involved in dorsal vessel development|positive regulation of global transcription from Pol II promoter involved in heart development|up-regulation of transcription from RNA polymerase II promoter involved in heart development|up-regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|up-regulation of global transcription from RNA polymerase II promoter involved in cardiac development|up regulation of transcription from RNA polymerase II promoter involved in cardiac development|positive regulation of transcription from Pol II promoter involved in heart development|positive regulation of transcription from RNA polymerase II promoter involved in cardiac development|up regulation of global transcription from RNA polymerase II promoter involved in heart development|activation of global transcription from RNA polymerase II promoter involved in dorsal vessel development|stimulation of global transcription from RNA polymerase II promoter involved in cardiac development|positive regulation of transcription from Pol II promoter involved in dorsal vessel development|positive regulation of global transcription from Pol II promoter involved in dorsal vessel development|activation of global transcription from RNA polymerase II promoter involved in cardiac development|upregulation of transcription from RNA polymerase II promoter involved in heart development|activation of transcription from RNA polymerase II promoter involved in cardiac development|upregulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|positive regulation of global transcription from Pol II promoter involved in cardiac development|up regulation of global transcription from RNA polymerase II promoter involved in dorsal vessel development|stimulation of transcription from RNA polymerase II promoter involved in cardiac development|upregulation of global transcription from RNA polymerase II promoter involved in heart development|up regulation of global transcription from RNA polymerase II promoter involved in cardiac development|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|up-regulation of transcription from RNA polymerase II promoter involved in cardiac development|stimulation of global transcription from RNA polymerase II promoter involved in heart development|up regulation of transcription from RNA polymerase II promoter involved in heart development|positive regulation of transcription from Pol II promoter involved in cardiac development|activation of transcription from RNA polymerase II promoter involved in heart development|up regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|upregulation of global transcription from RNA polymerase II promoter involved in dorsal vessel development|positive regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|stimulation of global transcription from RNA polymerase II promoter involved in dorsal vessel development|up-regulation of global transcription from RNA polymerase II promoter involved in heart development|upregulation of transcription from RNA polymerase II promoter involved in cardiac development|upregulation of global transcription from RNA polymerase II promoter involved in cardiac development|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|activation of transcription from RNA polymerase II promoter involved in dorsal vessel development|stimulation of transcription from RNA polymerase II promoter involved in heart development Any positive regulation of transcription from RNA polymerase II promoter that is involved in heart development. GO:1901229 regulation of non-canonical Wnt signaling pathway via JNK cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901229 regulation of non-canonical Wnt-activated signaling pathway via JNK cascade|regulation of non-canonical Wnt receptor signalling pathway via JNK cascade|regulation of non-canonical Wnt receptor signaling pathway via JNK cascade Any process that modulates the frequency, rate or extent of non-canonical Wnt signaling pathway via JNK cascade. GO:0046060 dATP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046060 dATP metabolism The chemical reactions and pathways involving dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate). GO:1901226 obsolete positive regulation of transcription from RNA polymerase II promoter involved in heart development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901226 up regulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|activation of regulation of global transcription from Pol II promoter involved in dorsal vessel development|upregulation of regulation of transcription from Pol II promoter involved in dorsal vessel development|upregulation of global transcription regulation from Pol II promoter involved in dorsal vessel development|up-regulation of global transcription regulation from Pol II promoter involved in heart development|positive regulation of regulation of transcription from Pol II promoter involved in cardiac development|up-regulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development|up regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|positive regulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|upregulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|activation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|activation of regulation of global transcription from Pol II promoter involved in cardiac development|positive regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|up regulation of regulation of transcription from Pol II promoter involved in cardiac development|up-regulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development|upregulation of global transcription regulation from Pol II promoter involved in cardiac development|up-regulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development|activation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|up-regulation of regulation of transcription from Pol II promoter involved in heart development|positive regulation of transcription from RNA polymerase II promoter involved in heart development|up regulation of regulation of transcription from RNA polymerase II promoter involved in heart development|activation of global transcription regulation from Pol II promoter involved in heart development|upregulation of regulation of global transcription from Pol II promoter involved in heart development|up regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|up-regulation of global transcription regulation from Pol II promoter involved in dorsal vessel development|activation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|activation of regulation of transcription from RNA polymerase II promoter involved in heart development|up regulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|up-regulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|up-regulation of regulation of transcription from Pol II promoter involved in dorsal vessel development|up-regulation of regulation of global transcription from Pol II promoter involved in cardiac development|positive regulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|upregulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development|positive regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|up-regulation of global transcription regulation from Pol II promoter involved in cardiac development|activation of regulation of transcription from Pol II promoter involved in heart development|up regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|up-regulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|upregulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development|positive regulation of global transcription regulation from Pol II promoter involved in heart development|upregulation of regulation of transcription from Pol II promoter involved in cardiac development|positive regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|up-regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|upregulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development|activation of regulation of transcription from Pol II promoter involved in dorsal vessel development|activation of global transcription regulation from Pol II promoter involved in dorsal vessel development|up regulation of global transcription regulation from Pol II promoter involved in heart development|activation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|activation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|upregulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|positive regulation of regulation of transcription from Pol II promoter involved in heart development|up regulation of regulation of global transcription from Pol II promoter involved in heart development|upregulation of regulation of global transcription from Pol II promoter involved in cardiac development|activation of global transcription regulation from Pol II promoter involved in cardiac development|up-regulation of regulation of transcription from RNA polymerase II promoter involved in heart development|positive regulation of regulation of global transcription from Pol II promoter involved in heart development|positive regulation of regulation of transcription from Pol II promoter involved in dorsal vessel development|positive regulation of global transcription regulation from Pol II promoter involved in dorsal vessel development|activation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|up regulation of regulation of transcription from Pol II promoter involved in heart development|up regulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development|up-regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|upregulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|up-regulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|up regulation of global transcription regulation from Pol II promoter involved in dorsal vessel development|up regulation of regulation of transcription from Pol II promoter involved in dorsal vessel development|up-regulation of regulation of transcription from Pol II promoter involved in cardiac development|up regulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development|positive regulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development|positive regulation of global transcription regulation from Pol II promoter involved in cardiac development|upregulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|upregulation of global transcription regulation from Pol II promoter involved in heart development|activation of regulation of global transcription from Pol II promoter involved in heart development|positive regulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development|up regulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development|up-regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|up regulation of global transcription regulation from Pol II promoter involved in cardiac development|positive regulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development|up regulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|activation of regulation of transcription from RNA polymerase II promoter, global involved in heart development|upregulation of regulation of transcription from RNA polymerase II promoter involved in heart development|activation of regulation of transcription from Pol II promoter involved in cardiac development|up regulation of regulation of global transcription from Pol II promoter involved in cardiac development|activation of regulation of transcription from RNA polymerase II promoter involved in cardiac development|positive regulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|upregulation of regulation of transcription from Pol II promoter involved in heart development|up-regulation of regulation of global transcription from Pol II promoter involved in heart development|upregulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|positive regulation of regulation of global transcription from Pol II promoter involved in cardiac development|upregulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development OBSOLETE. Any process that activates or increases the frequency, rate or extent of regulation of transcription from RNA polymerase II promoter involved in heart development. GO:1901227 negative regulation of transcription from RNA polymerase II promoter involved in heart development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901227 negative regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|down-regulation of global transcription from RNA polymerase II promoter involved in heart development|downregulation of transcription from RNA polymerase II promoter involved in cardiac development|inhibition of transcription from RNA polymerase II promoter involved in heart development|negative regulation of transcription from Pol II promoter involved in heart development|negative regulation of transcription from Pol II promoter involved in dorsal vessel development|negative regulation of global transcription from Pol II promoter involved in heart development|down-regulation of global transcription from RNA polymerase II promoter involved in dorsal vessel development|inhibition of transcription from RNA polymerase II promoter involved in dorsal vessel development|downregulation of global transcription from RNA polymerase II promoter involved in heart development|down-regulation of transcription from RNA polymerase II promoter involved in cardiac development|negative regulation of transcription from RNA polymerase II promoter involved in cardiac development|down-regulation of global transcription from RNA polymerase II promoter involved in cardiac development|negative regulation of global transcription from Pol II promoter involved in dorsal vessel development|down regulation of global transcription from RNA polymerase II promoter involved in heart development|down regulation of transcription from RNA polymerase II promoter involved in heart development|down regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|negative regulation of global transcription from Pol II promoter involved in cardiac development|downregulation of global transcription from RNA polymerase II promoter involved in dorsal vessel development|negative regulation of transcription from Pol II promoter involved in cardiac development|downregulation of transcription from RNA polymerase II promoter involved in heart development|downregulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|downregulation of global transcription from RNA polymerase II promoter involved in cardiac development|down regulation of global transcription from RNA polymerase II promoter involved in dorsal vessel development|inhibition of global transcription from RNA polymerase II promoter involved in heart development|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|inhibition of transcription from RNA polymerase II promoter involved in cardiac development|down regulation of global transcription from RNA polymerase II promoter involved in cardiac development|inhibition of global transcription from RNA polymerase II promoter involved in dorsal vessel development|down-regulation of transcription from RNA polymerase II promoter involved in heart development|negative regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|down-regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|down regulation of transcription from RNA polymerase II promoter involved in cardiac development|inhibition of global transcription from RNA polymerase II promoter involved in cardiac development Any negative regulation of transcription from RNA polymerase II promoter that is involved in heart development. GO:1901224 positive regulation of NIK/NF-kappaB signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901224 positive regulation of NF-kappaB import into nucleus|release of cytoplasmic sequestered NF-kappaB|positive regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|up regulation of p52-dependent NF-kappaB signaling|up regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|activation of non-canonical NF-KB signaling|positive regulation of p52-dependent NF-kappaB signaling|upregulation of noncanonical NF-kappaB signaling|release of NF-kappaB sequestered in cytoplasm|upregulation of NIK/NF-kappaB cascade|activation of p52-dependent NF-kappaB signaling|up-regulation of non-canonical NF-KB signaling|positive regulation of NIK/NF-kappaB cascade|up-regulation of noncanonical NF-kappaB signaling|upregulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|activation of NIK/NF-kappaB cascade|negative regulation of cytoplasmic NF-kappaB storage|up-regulation of p52-dependent NF-kappaB signaling|up regulation of NIK/NF-kappaB cascade|activation of noncanonical NF-kappaB signaling|upregulation of non-canonical NF-KB signaling|up-regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|positive regulation of noncanonical NF-kappaB signaling|upregulation of p52-dependent NF-kappaB signaling|up regulation of noncanonical NF-kappaB signaling|activation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|up-regulation of NIK/NF-kappaB cascade|up regulation of non-canonical NF-KB signaling|positive regulation of non-canonical NF-KB signaling Any process that activates or increases the frequency, rate or extent of NIK/NF-kappaB signaling. GO:1901225 obsolete negative regulation of transcription from RNA polymerase II promoter involved in heart development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901225 down regulation of global transcription regulation from Pol II promoter involved in cardiac development|down regulation of regulation of transcription from RNA polymerase II promoter involved in heart development|down regulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|down-regulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|negative regulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|down regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|negative regulation of regulation of global transcription from Pol II promoter involved in cardiac development|down-regulation of regulation of global transcription from Pol II promoter involved in cardiac development|inhibition of regulation of transcription from Pol II promoter involved in heart development|inhibition of regulation of global transcription from Pol II promoter involved in heart development|inhibition of regulation of transcription from Pol II promoter involved in dorsal vessel development|inhibition of global transcription regulation from Pol II promoter involved in dorsal vessel development|downregulation of regulation of transcription from RNA polymerase II promoter involved in heart development|negative regulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|downregulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|down regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|downregulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|down-regulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|inhibition of regulation of transcription from RNA polymerase II promoter, global involved in heart development|downregulation of regulation of transcription from Pol II promoter involved in cardiac development|negative regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|inhibition of global transcription regulation from Pol II promoter involved in cardiac development|down-regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|negative regulation of global transcription regulation from Pol II promoter involved in heart development|down-regulation of global transcription regulation from Pol II promoter involved in heart development|inhibition of regulation of transcription from RNA polymerase II promoter involved in cardiac development|downregulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|negative regulation of transcription from RNA polymerase II promoter involved in heart development|down regulation of regulation of transcription from Pol II promoter involved in cardiac development|down regulation of regulation of global transcription from Pol II promoter involved in heart development|inhibition of regulation of global transcription from Pol II promoter involved in dorsal vessel development|down regulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development|down-regulation of regulation of transcription from RNA polymerase II promoter involved in heart development|inhibition of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|negative regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|down-regulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|down-regulation of regulation of transcription from Pol II promoter involved in heart development|negative regulation of regulation of transcription from Pol II promoter involved in heart development|inhibition of regulation of global transcription from Pol II promoter involved in cardiac development|negative regulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|down-regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|downregulation of regulation of global transcription from Pol II promoter involved in heart development|down regulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development|negative regulation of regulation of transcription from Pol II promoter involved in dorsal vessel development|negative regulation of global transcription regulation from Pol II promoter involved in dorsal vessel development|down-regulation of regulation of transcription from Pol II promoter involved in dorsal vessel development|down-regulation of global transcription regulation from Pol II promoter involved in dorsal vessel development|inhibition of regulation of transcription from Pol II promoter involved in cardiac development|down regulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development|downregulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development|inhibition of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|downregulation of global transcription regulation from Pol II promoter involved in heart development|down-regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|negative regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|downregulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development|negative regulation of global transcription regulation from Pol II promoter involved in cardiac development|down-regulation of global transcription regulation from Pol II promoter involved in cardiac development|inhibition of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|inhibition of regulation of transcription from RNA polymerase II promoter involved in heart development|down regulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|downregulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development|down regulation of global transcription regulation from Pol II promoter involved in heart development|down regulation of regulation of global transcription from Pol II promoter involved in cardiac development|negative regulation of regulation of global transcription from Pol II promoter involved in heart development|downregulation of regulation of transcription from Pol II promoter involved in heart development|down-regulation of regulation of global transcription from Pol II promoter involved in heart development|downregulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|downregulation of global transcription regulation from Pol II promoter involved in dorsal vessel development|down regulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|downregulation of regulation of transcription from Pol II promoter involved in dorsal vessel development|downregulation of regulation of global transcription from Pol II promoter involved in cardiac development|down-regulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development|down regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|negative regulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development|inhibition of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|inhibition of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|down regulation of regulation of transcription from Pol II promoter involved in heart development|downregulation of global transcription regulation from Pol II promoter involved in cardiac development|down regulation of regulation of transcription from Pol II promoter involved in dorsal vessel development|downregulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|down regulation of global transcription regulation from Pol II promoter involved in dorsal vessel development|inhibition of global transcription regulation from Pol II promoter involved in heart development|down-regulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development|negative regulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development|down-regulation of regulation of transcription from Pol II promoter involved in cardiac development|negative regulation of regulation of transcription from Pol II promoter involved in cardiac development|down-regulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development|negative regulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development|downregulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|inhibition of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of regulation of transcription from RNA polymerase II promoter involved in heart development. GO:0046069 cGMP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046069 cGMP catabolism|cGMP breakdown|cGMP degradation The chemical reactions and pathways resulting in the breakdown of cyclic GMP, guanosine 3',5'-phosphate. GO:1901222 regulation of NIK/NF-kappaB signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901222 regulation of NIK/NF-kappaB cascade|NF-kappaB import into nucleus|regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|NF-KB import into nucleus|regulation of non-canonical NF-KB signaling|regulation of NF-kappaB import into nucleus|regulation of p52-dependent NF-kappaB signaling|regulation of noncanonical NF-kappaB signaling Any process that modulates the frequency, rate or extent of NIK/NF-kappaB signaling. GO:1901223 negative regulation of NIK/NF-kappaB signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901223 down regulation of noncanonical NF-kappaB signaling|down-regulation of non-canonical NF-KB signaling|negative regulation of NF-kappaB import into nucleus|negative regulation of non-canonical NF-KB signaling|downregulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|negative regulation of p52-dependent NF-kappaB signaling|down-regulation of p52-dependent NF-kappaB signaling|inhibition of noncanonical NF-kappaB signaling|down regulation of NIK/NF-kappaB cascade|down regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|downregulation of NIK/NF-kappaB cascade|inhibition of non-canonical NF-KB signaling|negative regulation of NIK/NF-kappaB cascade|inhibition of noncanonical nuclear factor kappaB (NF-kappaB) pathway|inhibition of p52-dependent NF-kappaB signaling|negative regulation of noncanonical NF-kappaB signaling|down-regulation of noncanonical NF-kappaB signaling|down-regulation of NIK/NF-kappaB cascade|down regulation of non-canonical NF-KB signaling|inhibition of NIK/NF-kappaB cascade|down regulation of p52-dependent NF-kappaB signaling|downregulation of non-canonical NF-KB signaling|down-regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|negative regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|downregulation of noncanonical NF-kappaB signaling|downregulation of p52-dependent NF-kappaB signaling Any process that stops, prevents or reduces the frequency, rate or extent of NIK/NF-kappaB signaling. GO:1901220 negative regulation of cardiac chamber morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901220 downregulation of heart chamber morphogenesis|down regulation of cardiac chamber morphogenesis|negative regulation of heart chamber morphogenesis|down-regulation of heart chamber morphogenesis|downregulation of cardiac chamber morphogenesis|inhibition of heart chamber morphogenesis|down-regulation of cardiac chamber morphogenesis|inhibition of cardiac chamber morphogenesis|down regulation of heart chamber morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber morphogenesis. GO:0046067 dGDP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046067 dGDP catabolism|dGDP degradation|dGDP breakdown The chemical reactions and pathways resulting in the breakdown of dGDP, deoxyguanosine diphosphate, (2'-deoxyguanosine 5'-diphosphate). GO:0046068 cGMP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046068 cGMP metabolism The chemical reactions and pathways involving cyclic GMP, guanosine 3',5'-phosphate. GO:1901221 positive regulation of cardiac chamber morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901221 up regulation of heart chamber morphogenesis|activation of heart chamber morphogenesis|upregulation of cardiac chamber morphogenesis|positive regulation of heart chamber morphogenesis|up regulation of cardiac chamber morphogenesis|activation of cardiac chamber morphogenesis|up-regulation of heart chamber morphogenesis|upregulation of heart chamber morphogenesis|up-regulation of cardiac chamber morphogenesis Any process that activates or increases the frequency, rate or extent of cardiac chamber morphogenesis. GO:1901230 negative regulation of non-canonical Wnt signaling pathway via JNK cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901230 down-regulation of non-canonical Wnt receptor signaling pathway via JNK cascade|down regulation of non-canonical Wnt receptor signalling pathway via JNK cascade|downregulation of non-canonical Wnt receptor signalling pathway via JNK cascade|downregulation of non-canonical Wnt receptor signaling pathway via JNK cascade|down regulation of non-canonical Wnt receptor signaling pathway via JNK cascade|down-regulation of non-canonical Wnt receptor signalling pathway via JNK cascade|negative regulation of non-canonical Wnt receptor signalling pathway via JNK cascade|inhibition of non-canonical Wnt receptor signaling pathway via JNK cascade|negative regulation of non-canonical Wnt-activated signaling pathway via JNK cascade|negative regulation of non-canonical Wnt receptor signaling pathway via JNK cascade|inhibition of non-canonical Wnt receptor signalling pathway via JNK cascade Any process that stops, prevents or reduces the frequency, rate or extent of non-canonical Wnt signaling pathway via JNK cascade. GO:0071029 nuclear ncRNA surveillance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071029 nuclear ncRNA quality control|nuclear aberrant ncRNA catabolic process The set of processes involved in identifying and degrading defective or aberrant ncRNAs within the nucleus. GO:0071027 nuclear RNA surveillance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071027 nuclear RNA quality control|nuclear aberrant RNA catabolic process The set of processes involved in identifying and degrading defective or aberrant RNAs within the nucleus. GO:0071028 nuclear mRNA surveillance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071028 nuclear mRNA quality control|nuclear aberrant mRNA catabolic process The set of processes involved in identifying and degrading defective or aberrant mRNAs within the nucleus. GO:0071025 RNA surveillance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071025 aberrant RNA catabolic process|RNA quality control The set of processes involved in identifying and degrading defective or aberrant RNAs. GO:0071026 cytoplasmic RNA surveillance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071026 cytoplasmic RNA quality control|cytoplasmic aberrant RNA catabolic process The set of processes involved in identifying and degrading defective or aberrant RNAs within the cytoplasm. GO:0071023 trans spliceosomal complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071023 A spliceosomal complex that forms during the addition of a specific spliced leader (SL) sequence to the 5'-end of a messenger RNA primary transcript, a process which occurs in a number of eukaryotic organisms, including trypanosomatid protozoans, euglenoids, nematodes, trematodes, and chordates. GO:0071024 SL snRNP biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071024 A ribonucleoprotein complex that contains spliced leader (SL) RNA and associated proteins. GO:0071010 prespliceosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071010 mammalian spliceosomal complex A|prespliceosomal complex|yeast spliceosomal complex B A spliceosomal complex that is formed by association of the 5' splice site and the branch point sequence with specific snRNPs. The prespliceosome includes many proteins in addition to those found in the bound snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation. Prespliceosome complexes are not active for splicing, but are instead an early step in the assembly of a spliceosomal complex. GO:0046076 dTTP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046076 dTTP degradation|dTTP breakdown|dTTP catabolism The chemical reactions and pathways resulting in the breakdown of dTTP, deoxyribosylthymine triphosphate. GO:0071011 precatalytic spliceosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071011 mammalian spliceosomal complex B|yeast spliceosomal complex A2-1|mammalian spliceosomal complex B1 A spliceosomal complex that is formed by the recruitment of a preassembled U5-containing tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the associated snRNPs. GO:0046077 dUDP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046077 dUDP metabolism The chemical reactions and pathways involving dUDP, deoxyuridine (5'-)diphosphate. GO:0046074 dTMP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046074 dTMP breakdown|dTMP catabolism|dTMP degradation The chemical reactions and pathways resulting in the breakdown of dTMP, deoxyribosylthymine monophosphate. GO:0046075 dTTP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046075 dTTP metabolism The chemical reactions and pathways involving dTTP, deoxyribosylthymine triphosphate. GO:0046072 dTDP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046072 dTDP metabolism The chemical reactions and pathways involving dTDP, deoxyribosylthymine diphosphate. GO:0046073 dTMP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046073 dTMP metabolism The chemical reactions and pathways involving dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate). GO:0046070 dGTP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046070 dGTP metabolism The chemical reactions and pathways involving dGTP, guanosine triphosphate. GO:1901239 malonate(1-) transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901239 RHEA:33115 malonic acid uptake transmembrane transporter activity Enables the transfer of malonate(1-) from one side of a membrane to the other. GO:0046071 dGTP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046071 dGTP synthesis|dGTP formation|dGTP biosynthesis|dGTP anabolism The chemical reactions and pathways resulting in the formation of dGTP, guanosine triphosphate. GO:1901237 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1901237 GO:1901238 ABC-type tungstate transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901238 EC:7.3.2.6|RHEA:35027 ATPase-coupled tungstate transmembrane transporter activity|tungstate transmembrane-transporting ATPase activity|tungstate transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + tungstate(in) = ADP + phosphate + tungstate(out). GO:1901235 (R)-carnitine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901235 RHEA:34959 Enables the transfer of (R)-carnitine from one side of a membrane to the other. GO:1901236 4-(trimethylammonio)butanoate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901236 RHEA:32835 Enables the transfer of 4-(trimethylammonio)butanoate from one side of a membrane to the other. GO:0061690 lipoamidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061690 MetaCyc:RXN-13031 lipoyl-X-hydrolase Catalysis of the cleavage of the amide bond to release lipoic acid from a lipoylated protein. GO:0061691 detoxification of hydrogen peroxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061691 Any process that reduces or removes the toxicity of hydrogen peroxide. These include transport of hydrogen peroxide away from sensitive areas and to compartments or complexes whose purpose is sequestration. GO:1901233 negative regulation of convergent extension involved in axis elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901233 down-regulation of convergent extension involved in axis elongation|downregulation of convergent extension involved in axis elongation|down regulation of convergent extension involved in axis elongation|inhibition of convergent extension involved in axis elongation Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in axis elongation. GO:0061692 cellular detoxification of hydrogen peroxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061692 Any process that reduces or removes the toxicity of hydrogen peroxide in a cell. These include transport of hydrogen peroxide away from sensitive areas and to compartments or complexes whose purpose is sequestration. GO:1901234 positive regulation of convergent extension involved in axis elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901234 up-regulation of convergent extension involved in axis elongation|activation of convergent extension involved in axis elongation|up regulation of convergent extension involved in axis elongation|upregulation of convergent extension involved in axis elongation Any process that activates or increases the frequency, rate or extent of convergent extension involved in axis elongation. GO:1901231 positive regulation of non-canonical Wnt signaling pathway via JNK cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901231 up-regulation of non-canonical Wnt receptor signalling pathway via JNK cascade|positive regulation of non-canonical Wnt receptor signaling pathway via JNK cascade|up-regulation of non-canonical Wnt receptor signaling pathway via JNK cascade|activation of non-canonical Wnt receptor signaling pathway via JNK cascade|upregulation of non-canonical Wnt receptor signalling pathway via JNK cascade|up regulation of non-canonical Wnt receptor signaling pathway via JNK cascade|positive regulation of non-canonical Wnt-activated signaling pathway via JNK cascade|up regulation of non-canonical Wnt receptor signalling pathway via JNK cascade|activation of non-canonical Wnt receptor signalling pathway via JNK cascade|positive regulation of non-canonical Wnt receptor signalling pathway via JNK cascade|upregulation of non-canonical Wnt receptor signaling pathway via JNK cascade Any process that activates or increases the frequency, rate or extent of non-canonical Wnt signaling pathway via JNK cascade. GO:0061693 alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061693 RHEA:34679|EC:2.7.8.37|MetaCyc:RXN0-6732 Catalysis of the reaction: ATP + methylphosphonate = alpha-D-ribose 1-methylphosphonate 5-triphosphate + adenine. GO:0046078 dUMP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046078 dUMP metabolism The chemical reactions and pathways involving dUMP, deoxyuridine (5'-)monophosphate (2'-deoxyuridine 5'-phosphate). GO:0046079 dUMP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046079 dUMP breakdown|dUMP catabolism|dUMP degradation The chemical reactions and pathways resulting in the breakdown of dUMP, deoxyuridine (5'-)monophosphate. GO:1901232 regulation of convergent extension involved in axis elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901232 Any process that modulates the frequency, rate or extent of convergent extension involved in axis elongation. GO:0061694 alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061694 A catalytic protein complex that is capable of alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity. GO:0061695 transferase complex, transferring phosphorus-containing groups biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061695 A transferase complex capable of catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor). GO:1901240 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1901240 GO:0061696 pituitary gonadotropin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061696 A protein complex that is a protein hormone secreted by gonadotrope cells of the anterior pituitary of vertebrates. capable of regulating normal growth, sexual development, and reproductive function. GO:1901241 4-hydroxyphenylacetate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901241 RHEA:33175 Enables the transfer of 4-hydroxyphenylacetate from one side of a membrane to the other. GO:0061697 protein-glutaryllysine deglutarylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061697 RHEA:47664 Catalysis of the reaction: H2O + N(6)-glutaryl-L-lysyl-[protein] + NAD(+) = 2''-O-glutaryl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide. GO:0061698 protein deglutarylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061698 The removal of a glutaryl group (CO-CH2-CH2-CH2-CO) from a residue in a peptide or protein. GO:0061699 peptidyl-lysine deglutarylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061699 The removal of a glutaryl group (CO-CH2-CH2--CH2-CO) from a glutarylated lysine residue in a peptide or protein. GO:0071018 U12-type catalytic step 2 spliceosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071018 mammalian U12-type spliceosomal complex C|yeast U12-type spliceosomal complex A2-2|minor catalytic step 2 spliceosome|AT-AC catalytic step 2 spliceosome|mammalian U12-type spliceosomal complex C1 A spliceosomal complex that contains the U12, U5 and U6atac snRNPs bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the U12, U5 and U6atac snRNPs. GO:0071019 U12-type post-mRNA release spliceosomal complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071019 minor post-mRNA release spliceosomal complex|AT-AC post-mRNA release spliceosomal complex|mammalian U12-type spliceosomal complex I A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and the U12, U5 and U6atac snRNPs. GO:0046080 dUTP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046080 dUTP metabolism The chemical reactions and pathways involving dUTP, deoxyuridine (5'-)triphosphate. GO:0071016 U12-type precatalytic spliceosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071016 mammalian U12-type spliceosomal complex B|yeast U12-type spliceosomal complex A2-1|mammalian U12-type spliceosomal complex B1|minor precatalytic spliceosome|AT-AC precatalytic spliceosome A spliceosomal complex that is formed by the recruitment of the preassembled U4atac/U6atac.U5 tri-snRNP to the U12-type prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the U11, U12 and U4atac/U6atac.U5 snRNPs. GO:0071017 U12-type catalytic step 1 spliceosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071017 minor catalytic step 1 spliceosome|AT-AC catalytic step 1 spliceosome|yeast U12-type spliceosomal complex A1|mammalian U12-type spliceosomal complex B2|U12-type activated spliceosome|mammalian U12-type spliceosomal complex B* A spliceosomal complex that is formed by the displacement of the U11 and U4atac snRNPs from the precatalytic spliceosome; the U12, U5 and U6atac snRNPs remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the U12, and U5 and U6atac snRNPs. GO:0071014 post-mRNA release spliceosomal complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071014 mammalian spliceosomal complex I A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and three snRNPs, including U5. GO:0071015 U12-type prespliceosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071015 mammalian U12-type spliceosomal complex A|minor prespliceosome|AT-AC prespliceosome|yeast U12-type spliceosomal complex B A spliceosomal complex that is formed by the cooperative binding of the heterodimeric U11/U12 snRNP to the 5' splice site and the branch point sequence. The U12-type prespliceosome includes many proteins in addition to those found in the U11/U12 heterodimeric snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation. GO:0071012 catalytic step 1 spliceosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071012 activated spliceosome|mammalian spliceosomal complex B2|yeast spliceosomal complex A1|mammalian spliceosomal complex B* A spliceosomal complex that is formed by the displacement of the two snRNPs from the precatalytic spliceosome; three snRNPs including U5 remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the associated snRNPs. GO:0071013 catalytic step 2 spliceosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071013 mammalian spliceosomal complex C|yeast spliceosomal complex A2-2|mammalian spliceosomal complex C1 A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs. GO:0071043 CUT metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071043 The chemical reactions and pathways involving cryptic unstable transcripts (CUTs), which are transcribed from intergenic regions. Many intergenic regions are heavily transcribed, but the transcripts are rarely detected due to rapid degradation by the nuclear exosome. GO:0046087 cytidine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046087 cytidine metabolism The chemical reactions and pathways involving cytidine, cytosine riboside, a widely distributed nucleoside. GO:0022032 telencephalon oligodendrocyte cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022032 The multiplication or reproduction of telencephalon oligodendrocyte cells, resulting in the expansion of a cell population. GO:0071044 histone mRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071044 The chemical reactions and pathways resulting in the breakdown of histone messenger RNA (mRNA). CHEBI:9053 sclareol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_9053 GO:0046088 cytidine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046088 cytidine anabolism|cytidine synthesis|cytidine formation|cytidine biosynthesis The chemical reactions and pathways resulting in the formation of cytidine, cytosine riboside, a widely distributed nucleoside. GO:0022033 telencephalon microglial cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022033 The orderly movement of microglial cells through the telencephalon. GO:0071041 antisense RNA transcript catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071041 The chemical reactions and pathways resulting in the breakdown of antisense transcripts, i.e. transcripts that were produced from the antisense strand of a gene that produces a gene product and which often have a regulatory effect on the transcription of that gene product. GO:0022034 rhombomere cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022034 The multiplication or reproduction of rhombomere cells, resulting in the expansion of the cell population. GO:0046085 adenosine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046085 adenosine metabolism The chemical reactions and pathways involving adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes. GO:0071042 nuclear polyadenylation-dependent mRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071042 nuclear poly(A)-dependent mRNA catabolic process The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA. GO:0022035 rhombomere cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022035 The movement of a cell within a rhombomere. This process is known to occur as an early step in the generation of anatomical structure from a rhombomere. GO:0046086 adenosine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046086 adenosine formation|adenosine biosynthesis|adenosine anabolism|adenosine synthesis The chemical reactions and pathways resulting in the formation of adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes. GO:0022036 rhombomere cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022036 The process in which a relatively unspecialized cell acquires specialized features of a rhombomere cell. GO:0046083 adenine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046083 adenine metabolism The chemical reactions and pathways involving adenine, 6-aminopurine, one of the five main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine. GO:0022037 metencephalon development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022037 The process whose specific outcome is the progression of the metencephalon over time, from its formation to the mature structure. GO:0071040 nuclear polyadenylation-dependent antisense transcript catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071040 nuclear poly(A)-dependent antisense transcript catabolic process The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of an antisense transcript, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target antisense transcript. GO:0046084 adenine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046084 adenine biosynthesis|adenine anabolism|adenine synthesis|adenine formation The chemical reactions and pathways resulting in the formation of adenine, 6-aminopurine, one of the five main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine. GO:0046081 dUTP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046081 dUTP degradation|dUTP breakdown|dUTP catabolism The chemical reactions and pathways resulting in the breakdown of dUTP, deoxyuridine (5'-)triphosphate. GO:0022038 corpus callosum development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022038 The process whose specific outcome is the progression of the corpus callosum over time, from its formation to the mature structure. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provide communication between the right and left cerebral hemispheres. GO:0046082 5-methylcytosine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046082 5-methylcytosine biosynthesis|5-methylcytosine anabolism|5-methylcytosine synthesis|5-methylcytosine formation The chemical reactions and pathways resulting in the formation of 5-methylcytosine, a methylated base of DNA. OBO:GOCHE_52208 substance with biophysical role role biolink:OntologyClass go-plus 1_STAR http://purl.obolibrary.org/obo/GOCHE_52208 GO:1901248 positive regulation of lung ciliated cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901248 up regulation of lung ciliated cell differentiation|upregulation of lung ciliated cell differentiation|up-regulation of lung ciliated cell differentiation|activation of lung ciliated cell differentiation Any process that activates or increases the frequency, rate or extent of lung ciliated cell differentiation. GO:1901249 regulation of lung goblet cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901249 regulation of pulmonary goblet cell differentiation Any process that modulates the frequency, rate or extent of lung goblet cell differentiation. GO:1901246 regulation of lung ciliated cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901246 Any process that modulates the frequency, rate or extent of lung ciliated cell differentiation. OBO:GOCHE_52206 substance with biochemical role role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_52206 GO:1901247 negative regulation of lung ciliated cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901247 down-regulation of lung ciliated cell differentiation|downregulation of lung ciliated cell differentiation|down regulation of lung ciliated cell differentiation|inhibition of lung ciliated cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of lung ciliated cell differentiation. GO:1901244 obsolete positive regulation of transcription from RNA polymerase II promoter involved in defense response to fungus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901244 activation of global transcription from RNA polymerase II promoter involved in defense response to fungi|positive regulation of global transcription from Pol II promoter involved in defense response to fungus|upregulation of global transcription from RNA polymerase II promoter involved in defence response to fungi|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defence response to fungus|up-regulation of transcription from RNA polymerase II promoter involved in defense response to fungi|upregulation of global transcription from RNA polymerase II promoter involved in defence response to fungus|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defence response to fungi|positive regulation of global transcription from Pol II promoter involved in defense response to fungi|activation of global transcription from RNA polymerase II promoter involved in defense response to fungus|stimulation of global transcription from RNA polymerase II promoter involved in defence response to fungi|positive regulation of transcription from Pol II promoter involved in defence response to fungus|up regulation of transcription from RNA polymerase II promoter involved in defense response to fungus|up regulation of transcription from RNA polymerase II promoter involved in defence response to fungi|positive regulation of transcription from Pol II promoter involved in defense response to fungi|positive regulation of transcription from RNA polymerase II promoter involved in defence response to fungi|up-regulation of transcription from RNA polymerase II promoter involved in defence response to fungus|activation of transcription from RNA polymerase II promoter involved in defence response to fungi|up regulation of global transcription from RNA polymerase II promoter involved in defense response to fungi|activation of transcription from RNA polymerase II promoter involved in defence response to fungus|up-regulation of global transcription from RNA polymerase II promoter involved in defense response to fungus|stimulation of transcription from RNA polymerase II promoter involved in defence response to fungus|up-regulation of global transcription from RNA polymerase II promoter involved in defence response to fungi|upregulation of transcription from RNA polymerase II promoter involved in defense response to fungi|stimulation of global transcription from RNA polymerase II promoter involved in defence response to fungus|up regulation of global transcription from RNA polymerase II promoter involved in defence response to fungus|upregulation of transcription from RNA polymerase II promoter involved in defense response to fungus|stimulation of transcription from RNA polymerase II promoter involved in defence response to fungi|activation of global transcription from RNA polymerase II promoter involved in defence response to fungi|upregulation of global transcription from RNA polymerase II promoter involved in defense response to fungi|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defense response to fungus|positive regulation of global transcription from Pol II promoter involved in defence response to fungus|positive regulation of global transcription from Pol II promoter involved in defence response to fungi|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defense response to fungi|positive regulation of transcription from RNA polymerase II promoter involved in defence response to fungus|up-regulation of transcription from RNA polymerase II promoter involved in defence response to fungi|upregulation of global transcription from RNA polymerase II promoter involved in defense response to fungus|stimulation of global transcription from RNA polymerase II promoter involved in defense response to fungi|activation of global transcription from RNA polymerase II promoter involved in defence response to fungus|positive regulation of transcription from Pol II promoter involved in defense response to fungus|up regulation of transcription from RNA polymerase II promoter involved in defence response to fungus|up regulation of transcription from RNA polymerase II promoter involved in defense response to fungi|positive regulation of transcription from Pol II promoter involved in defence response to fungi|up-regulation of transcription from RNA polymerase II promoter involved in defense response to fungus|activation of transcription from RNA polymerase II promoter involved in defense response to fungi|up regulation of global transcription from RNA polymerase II promoter involved in defence response to fungi|positive regulation of transcription from RNA polymerase II promoter involved in defense response to fungi|activation of transcription from RNA polymerase II promoter involved in defense response to fungus|up-regulation of global transcription from RNA polymerase II promoter involved in defence response to fungus|up-regulation of global transcription from RNA polymerase II promoter involved in defense response to fungi|stimulation of transcription from RNA polymerase II promoter involved in defense response to fungus|upregulation of transcription from RNA polymerase II promoter involved in defence response to fungi|up regulation of global transcription from RNA polymerase II promoter involved in defense response to fungus|stimulation of global transcription from RNA polymerase II promoter involved in defense response to fungus|upregulation of transcription from RNA polymerase II promoter involved in defence response to fungus|stimulation of transcription from RNA polymerase II promoter involved in defense response to fungi OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter to protect the cell or organism in response to the presence of a fungus. GO:1901245 positive regulation of toll-like receptor 9 signaling pathway by B cell receptor internalization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901245 BCR-induced TLR9 recruitment|positive regulation of toll-like receptor 9 signaling pathway by BCR receptor internalization|positive regulation of TLR9 signaling pathway by BCR endocytosis|positive regulation of toll-like receptor 9 signalling pathway by BCR endocytosis|positive regulation of toll-like receptor 9 signalling pathway by BCR receptor internalization|positive regulation of TLR9 signaling pathway by B cell receptor internalization|positive regulation of toll-like receptor 9 signalling pathway by B cell receptor internalization|positive regulation of TLR9 signaling pathway by BCR receptor internalization|positive regulation of toll-like receptor 9 signaling pathway by BCR endocytosis The movement of a B cell receptor (BCR) from the plasma membrane to the inside of the cell, which results in positive regulation of toll-like receptor 9 (TLR9) signaling. For example, internalized BCR signals to recruit TLR9 from multiple small endosomes to large autophagosome-like compartments to enhance TLR9 signaling. GO:1901242 ABC-type doxorubicin transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901242 TC:3.A.1.105.1 ATPase-coupled doxorubicin transmembrane transporter activity|doxorubicin transmembrane-transporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + doxorubicin(in) = ADP + phosphate + doxorubicin(out). GO:0022030 telencephalon glial cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022030 The orderly movement of glial cells through the telencephalon. GO:0046089 cytosine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046089 cytosine anabolism|cytosine synthesis|cytosine formation|cytosine biosynthesis The chemical reactions and pathways resulting in the formation of cytosine, 4-amino-2-hydroxypyrimidine, a pyrimidine derivative that is one of the five main bases found in nucleic acids; it occurs widely in cytidine derivatives. GO:0022031 telencephalon astrocyte cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022031 The orderly movement of an astrocyte cell through the telencephalon. GO:1901243 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1901243 GO:1901251 positive regulation of lung goblet cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901251 upregulation of pulmonary goblet cell differentiation|upregulation of lung goblet cell differentiation|up regulation of pulmonary goblet cell differentiation|positive regulation of pulmonary goblet cell differentiation|activation of pulmonary goblet cell differentiation|up-regulation of lung goblet cell differentiation|activation of lung goblet cell differentiation|up-regulation of pulmonary goblet cell differentiation|up regulation of lung goblet cell differentiation Any process that activates or increases the frequency, rate or extent of lung goblet cell differentiation. OBO:GOCHE_52211 substance with physiological role role biolink:OntologyClass go-plus 1_STAR http://purl.obolibrary.org/obo/GOCHE_52211 GO:1901252 regulation of intracellular transport of viral material biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901252 regulation of viral egress|regulation of movement of virus within host cell|regulation of egress of virus within host cell Any process that modulates the frequency, rate or extent of egress of virus within host cell. GO:1901250 negative regulation of lung goblet cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901250 downregulation of lung goblet cell differentiation|down regulation of lung goblet cell differentiation|inhibition of lung goblet cell differentiation|down regulation of pulmonary goblet cell differentiation|downregulation of pulmonary goblet cell differentiation|down-regulation of pulmonary goblet cell differentiation|negative regulation of pulmonary goblet cell differentiation|down-regulation of lung goblet cell differentiation|inhibition of pulmonary goblet cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of lung goblet cell differentiation. OBO:GOCHE_52210 substance with pharmacological role role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_52210 GO:0046090 deoxyadenosine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046090 deoxyadenosine metabolism The chemical reactions and pathways involving deoxyadenosine, 2-deoxyribosyladenine, one of the four major nucleosides of DNA. GO:0046091 deoxyadenosine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046091 deoxyadenosine biosynthesis|deoxyadenosine anabolism|deoxyadenosine synthesis|deoxyadenosine formation The chemical reactions and pathways resulting in the formation of deoxyadenosine, 2-deoxyribosyladenine, one of the four major nucleosides of DNA. GO:0071049 nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071049 The process involved in retention of mRNAs that have incorrectly formed 3'-ends within the nucleus at the site of transcription. GO:0071047 polyadenylation-dependent mRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071047 poly(A)-dependent mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA. GO:0071048 nuclear retention of unspliced pre-mRNA at the site of transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071048 The process involved in retention of incorrectly or incompletely spliced pre-mRNA within the nucleus at the site of transcription. GO:0071045 nuclear histone mRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071045 The chemical reactions and pathways resulting in the breakdown of histone messenger RNA (mRNA) within the nucleus. GO:0071046 nuclear polyadenylation-dependent ncRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071046 nuclear poly(A)-dependent ncRNA catabolic process The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a noncoding RNA (ncRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target ncRNA. GO:0022021 caudal ganglionic eminence cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022021 The multiplication or reproduction of caudal ganglionic eminence cells, resulting in the expansion of a cell population. GO:0046098 guanine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046098 guanine metabolism The chemical reactions and pathways involving guanine, 2-amino-6-hydroxypurine, a purine that is one of the five main bases found in nucleic acids and a component of a number of phosphorylated guanosine derivatives whose metabolic or regulatory functions are important. GO:0071032 nuclear mRNA surveillance of mRNP export biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071032 nuclear mRNA quality control of mRNAs in aberrant mRNPs|nuclear mRNA catabolic process of mRNAs in aberrant mRNPs The set of processes involved in identifying and degrading incorrectly formed or aberrant nuclear mRNPs docked at the nuclear pore complex prior to export to the cytoplasm. CHEBI:145992 orlandin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_145992 GO:0022022 septal cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022022 septum cell proliferation The multiplication or reproduction of septal cells, resulting in the expansion of a cell population. GO:0046099 guanine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046099 guanine biosynthesis|guanine anabolism|guanine synthesis|guanine formation The chemical reactions and pathways resulting in the formation of guanine, 2-amino-6-hydroxypurine, a purine that is one of the five main bases found in nucleic acids and a component of a number of phosphorylated guanosine derivatives whose metabolic or regulatory functions are important. GO:0071033 nuclear retention of pre-mRNA at the site of transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071033 The process involved in retention of aberrant or improperly formed mRNAs, e.g. those that are incorrectly or incompletely spliced or that have incorrectly formed 3'-ends, within the nucleus at the site of transcription. GO:0071030 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071030 nuclear RNA catabolic process of incorrectly spliced pre-mRNA|nuclear mRNA quality control of incorrectly spliced pre-mRNA The set of processes involved in identifying and degrading incorrectly spliced pre-mRNAs within the nucleus. GO:0046096 deoxyuridine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046096 deoxyuridine metabolism The chemical reactions and pathways involving deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA. GO:0022023 radial glial cell fate commitment in forebrain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022023 The process in which the developmental fate of a cell becomes restricted such that it will develop into a radial glial cell in the forebrain. GO:0046097 deoxyuridine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046097 deoxyuridine anabolism|deoxyuridine synthesis|deoxyuridine formation|deoxyuridine biosynthesis The chemical reactions and pathways resulting in the formation of deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA. GO:0022024 BMP signaling pathway involved in forebrain neuron fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022024 bone morphogenetic protein signaling pathway involved in forebrain neuron fate commitment|BMP signalling pathway involved in forebrain neuron fate commitment|bone morphogenetic protein signalling pathway involved in forebrain neuron fate commitment A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain. GO:0071031 nuclear mRNA surveillance of mRNA 3'-end processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071031 nuclear mRNA quality control of mRNAs with aberrant 3'-ends|nuclear mRNA catabolic process of mRNA with aberrant 3'-ends The set of processes involved in identifying and degrading mRNAs with incorrectly formed 3'-ends within the nucleus. CHEBI:9066 L-adenosylselenomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_9066 GO:0046094 deoxyinosine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046094 deoxyinosine metabolism The chemical reactions and pathways involving deoxyinosine, hypoxanthine deoxyriboside. GO:0022025 leukemia inhibitory factor signaling pathway involved in forebrain neuron fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022025 leukemia inhibitory factor signalling pathway involved in forebrain neuron fate commitment Any series of molecular signals initiated by the binding of leukemia inhibitory factor to a receptor on the surface of the target cell, that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain. GO:0046095 deoxyinosine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046095 deoxyinosine biosynthesis|deoxyinosine anabolism|deoxyinosine synthesis|deoxyinosine formation The chemical reactions and pathways resulting in the formation of deoxyinosine, hypoxanthine deoxyriboside. GO:0022026 epidermal growth factor signaling pathway involved in forebrain neuron fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022026 epidermal growth factor signalling pathway involved in forebrain neuron fate commitment The series of molecular signals generated as a consequence of a epidermal growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain. GO:0046092 deoxycytidine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046092 deoxycytidine metabolism The chemical reactions and pathways involving deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA. GO:0022027 interkinetic nuclear migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022027 The movement of the nucleus of the ventricular zone cell between the apical and the basal zone surfaces. Mitosis occurs when the nucleus is near the apical surface, that is, the lumen of the ventricle. GO:0046093 deoxycytidine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046093 deoxycytidine anabolism|deoxycytidine synthesis|deoxycytidine formation|deoxycytidine biosynthesis The chemical reactions and pathways resulting in the formation of deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA. CHEBI:9062 scutellarein biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_9062 GO:0022028 tangential migration from the subventricular zone to the olfactory bulb biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022028 rostral migratory stream migration The migration of cells in the telencephalon from the subventricular zone to the olfactory bulb in which cells move orthogonally to the direction of radial migration and do not use radial glial cell processes as substrates for migration. GO:1901259 chloroplast rRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901259 Any rRNA processing that takes place in chloroplast. GO:1901257 negative regulation of macrophage colony-stimulating factor production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901257 down regulation of macrophage colony-stimulating factor production|downregulation of macrophage colony-stimulating factor production|downregulation of M-CSF production|down regulation of M-CSF production|down-regulation of macrophage colony-stimulating factor production|inhibition of M-CSF production|inhibition of macrophage colony-stimulating factor production|down-regulation of M-CSF production|negative regulation of M-CSF production Any process that stops, prevents or reduces the frequency, rate or extent of macrophage colony-stimulating factor production. GO:1901258 positive regulation of macrophage colony-stimulating factor production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901258 positive regulation of M-CSF production|up regulation of M-CSF production|up regulation of macrophage colony-stimulating factor production|activation of macrophage colony-stimulating factor production|upregulation of M-CSF production|up-regulation of macrophage colony-stimulating factor production|up-regulation of M-CSF production|activation of M-CSF production|upregulation of macrophage colony-stimulating factor production Any process that activates or increases the frequency, rate or extent of macrophage colony-stimulating factor production. GO:1901255 nucleotide-excision repair involved in interstrand cross-link repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901255 nucleotide-excision repair involved in ICL repair|NER involved in ICL repair|NER involved in interstrand cross-link repair Any nucleotide-excision repair that is involved in interstrand cross-link repair. GO:1901256 regulation of macrophage colony-stimulating factor production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901256 regulation of M-CSF production Any process that modulates the frequency, rate or extent of macrophage colony-stimulating factor production. GO:1901253 negative regulation of intracellular transport of viral material biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901253 down-regulation of movement of virus within host cell|negative regulation of movement of virus within host cell|down regulation of viral egress|downregulation of egress of virus within host cell|down regulation of egress of virus within host cell|downregulation of movement of virus within host cell|inhibition of egress of virus within host cell|inhibition of viral egress|down regulation of movement of virus within host cell|negative regulation of egress of virus within host cell|inhibition of movement of virus within host cell|negative regulation of viral egress|down-regulation of viral egress|down-regulation of egress of virus within host cell|downregulation of viral egress Any process that stops, prevents or reduces the frequency, rate or extent of intracellular transport of viral material. GO:1901254 positive regulation of intracellular transport of viral material biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901254 up regulation of egress of virus within host cell|positive regulation of movement of virus within host cell|upregulation of viral egress|up regulation of movement of virus within host cell|upregulation of egress of virus within host cell|up-regulation of viral egress|upregulation of movement of virus within host cell|up-regulation of egress of virus within host cell|positive regulation of egress of virus within host cell|activation of viral egress|activation of egress of virus within host cell|up-regulation of movement of virus within host cell|positive regulation of viral egress|up regulation of viral egress|activation of movement of virus within host cell Any process that activates or increases the frequency, rate or extent of intracellular transport of viral material. GO:0022020 medial ganglionic eminence cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022020 The multiplication or reproduction of medial ganglionic eminence cells, resulting in the expansion of a cell population. GO:1901262 negative regulation of sorocarp spore cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901262 inhibition of sorocarp spore cell differentiation|down regulation of sorocarp spore cell differentiation|downregulation of sorocarp spore cell differentiation|down-regulation of sorocarp spore cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of sorocarp spore cell differentiation. GO:1901263 positive regulation of sorocarp spore cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901263 up-regulation of sorocarp spore cell differentiation|upregulation of sorocarp spore cell differentiation|up regulation of sorocarp spore cell differentiation|activation of sorocarp spore cell differentiation Any process that activates or increases the frequency, rate or extent of sorocarp spore cell differentiation. GO:1901260 peptidyl-lysine hydroxylation involved in bacterial-type EF-P lysine modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901260 EF-P lysine hydroxylation Any peptidyl-lysine hydroxylation that is involved in bacterial-type EF-P lysine modification. GO:1901261 regulation of sorocarp spore cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901261 Any process that modulates the frequency, rate or extent of sorocarp spore cell differentiation. CHEBI:131367 3-hydroxy-3-butenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131367 GO:0022029 telencephalon cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022029 The orderly movement of a cell from one site to another at least one of which is located in the telencephalon. GO:0071038 nuclear polyadenylation-dependent tRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071038 nuclear poly(A)-dependent tRNA catabolic process The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of an aberrant or incorrectly modified transfer RNA (tRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target tRNA. GO:0071039 nuclear polyadenylation-dependent CUT catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071039 nuclear poly(A)-dependent CUT catabolic process The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a cryptic unstable transcript (CUT), initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target CUT. GO:0071036 nuclear polyadenylation-dependent snoRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071036 nuclear poly(A)-dependent snoRNA catabolic process The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a small nucleolar RNA (snoRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target snoRNA. GO:0071037 nuclear polyadenylation-dependent snRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071037 nuclear poly(A)-dependent snRNA catabolic process The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a small nuclear RNA (snRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target snRNA. GO:0071034 CUT catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071034 cryptic unstable transcript catabolic process The chemical reactions and pathways resulting in the breakdown of cryptic unstable transcripts (CUTs). GO:0071035 nuclear polyadenylation-dependent rRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071035 nuclear poly(A)-dependent rRNA catabolic process The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a ribosomal RNA (rRNA) molecule, including RNA fragments released as part of processing the primary transcript into multiple mature rRNA species, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA. GO:0022010 central nervous system myelination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022010 myelination in central nervous system The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of oligodendrocytes in the central nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier. GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071065 ITGA9-ITGB1-VCAM1 complex A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular cell adhesion molecule-1. GO:0022011 myelination in peripheral nervous system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022011 peripheral nervous system myelination The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of Schwann cells in the peripheral nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier. GO:0071066 detection of mechanical stimulus involved in sensory perception of wind biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071066 perception of wind, sensory detection of mechanical stimulus|perception of wind, detection of mechanical stimulus|perception of wind, sensory transduction of mechanical stimulus|sensory transduction of mechanical stimulus during perception of wind|detection of mechanical stimulus involved in sensory perception of air flow|detection of wind|sensory detection of mechanical stimulus during perception of wind|sensory transduction of wind The series of events involved in the perception of wind in which a mechanical stimulus is received and converted into a molecular signal. GO:0071063 sensory perception of wind biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071063 perception of wind|sensory perception of air flow The series of events required for an organism to receive sensory mechanical stimulus resulting from air flow, convert it to a molecular signal, and recognize and characterize the signal. GO:0022012 subpallium cell proliferation in forebrain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022012 The multiplication or reproduction of subpallium cells in the forebrain, resulting in the expansion of a cell population. GO:0071064 alphaE-beta7 integrin-E-cadherin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071064 ITGAE-ITGB7-CDH1 complex A protein complex that consists of an alphaE-beta7 integrin complex bound to E-cadherin. GO:0022013 pallium cell proliferation in forebrain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022013 The multiplication or reproduction of pallium cells in the forebrain, resulting in the expansion of the cell population. GO:0071061 alpha6-beta4 integrin-CD151 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071061 ITGA6-ITGB4-CD151 complex A protein complex that consists of an alpha6-beta4 integrin complex bound to the tetraspanin CD151. GO:0022014 obsolete radial glial cell division in subpallium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022014 OBSOLETE. The division of a radial glial cell in the subpallium. A radial glial cell is a precursor cell that gives rise to neurons and astrocytes. GO:0071062 alphav-beta3 integrin-vitronectin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071062 ITGAV-ITGB3-VTN complex A protein complex that consists of an alphav-beta3 integrin complex bound to vitronectin. GO:0022015 radial glial cell division in pallium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022015 The division of a radial glial cell in the pallium. A radial glial cell is a precursor cell that gives rise to neurons and astrocytes. GO:0022016 pallium glioblast division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022016 glioblast cell division in pallium The division of a glioblast in the pallium. A glioblast is a dividing precursor cell that gives rise to glial cells. GO:0071060 alpha7-beta1 integrin-CD151 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071060 ITGA7-ITGB1-CD151 complex A protein complex that consists of an alpha7-beta1 integrin complex bound to the tetraspanin CD151. GO:0022017 neuroblast division in pallium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022017 The division of neuroblasts in the pallium. Neuroblasts are precursor cells that give rise to neurons. GO:1901268 cephalosporin C biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901268 cephalosporin C anabolism|cephalosporin C synthesis|cephalosporin C formation|cephalosporin C biosynthesis The chemical reactions and pathways resulting in the formation of cephalosporin C. GO:1901269 lipooligosaccharide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901269 lipooligosaccharide metabolism The chemical reactions and pathways involving lipooligosaccharide. GO:1901266 cephalosporin C metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901266 cephalosporin C metabolism The chemical reactions and pathways involving cephalosporin C. GO:1901267 cephalosporin C catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901267 cephalosporin C catabolism|cephalosporin C degradation|cephalosporin C breakdown The chemical reactions and pathways resulting in the breakdown of cephalosporin C. GO:1901264 carbohydrate derivative transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901264 The directed movement of a carbohydrate derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:1901265 nucleoside phosphate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901265 Interacting selectively and non-covalently with nucleoside phosphate. GO:1901273 2-dehydro-3-deoxy-D-gluconic acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901273 2-dehydro-3-deoxy-D-gluconic acid breakdown|2-dehydro-3-deoxy-D-gluconic acid catabolism|2-dehydro-3-deoxy-D-gluconic acid degradation The chemical reactions and pathways resulting in the breakdown of 2-dehydro-3-deoxy-D-gluconic acid. GO:1901274 2-dehydro-3-deoxy-D-gluconic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901274 2-dehydro-3-deoxy-D-gluconic acid biosynthesis|2-dehydro-3-deoxy-D-gluconic acid anabolism|2-dehydro-3-deoxy-D-gluconic acid synthesis|2-dehydro-3-deoxy-D-gluconic acid formation The chemical reactions and pathways resulting in the formation of 2-dehydro-3-deoxy-D-gluconic acid. GO:1901271 lipooligosaccharide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901271 lipooligosaccharide biosynthesis|lipooligosaccharide anabolism|lipooligosaccharide synthesis|lipooligosaccharide formation The chemical reactions and pathways resulting in the formation of lipooligosaccharide. GO:1901272 2-dehydro-3-deoxy-D-gluconic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901272 2-dehydro-3-deoxy-D-gluconic acid metabolism The chemical reactions and pathways involving 2-dehydro-3-deoxy-D-gluconic acid. GO:1901270 lipooligosaccharide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901270 lipooligosaccharide breakdown|lipooligosaccharide catabolism|lipooligosaccharide degradation The chemical reactions and pathways resulting in the breakdown of lipooligosaccharide. GO:0022018 lateral ganglionic eminence cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022018 The multiplication or reproduction of lateral ganglionic eminence cells, resulting in the expansion of the cell population. CHEBI:145989 3-phosphonatoshikimate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_145989 GO:0022019 dorsal lateral ganglionic eminence cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022019 The multiplication or reproduction of dorsal lateral ganglionic eminence cells, resulting in the expansion of the cell population. GO:0071069 alpha4-beta1 integrin-thrombospondin-1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071069 ITGA4-ITGB1-THBS1 complex A protein complex that consists of an alpha4-beta1 integrin complex bound to thrombospondin-1. GO:0071067 alphav-beta3 integrin-ADAM23 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071067 ITGAV-ITGB3-ADAM23 complex A protein complex that consists of an alphav-beta3 integrin complex bound to the transmembrane metallopeptidase ADAM23. GO:0071068 alpha9-beta1 integrin-ADAM12 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071068 ITGA9-ITGB1-ADAM12 complex A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM12. GO:0071054 alpha9-beta1 integrin-ADAM3 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071054 ITGA9-ITGB1-ADAM3 complex A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM3. GO:0071055 alpha9-beta1 integrin-ADAM9 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071055 ITGA9-ITGB1-ADAM9 complex A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM9. GO:0022000 forebrain induction by the anterior neural ridge biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022000 The close range interaction of the anterior neural ridge to the caudal region of the neural plate that specifies the forebrain fate. GO:0071052 alpha9-beta1 integrin-ADAM1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071052 ITGA9-ITGB1-ADAM1 complex A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM1. GO:0022001 negative regulation of anterior neural cell fate commitment of the neural plate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022001 down regulation of anterior neural cell fate of the neural plate|negative regulation of anterior neural cell fate of the neural plate|caudalization of neural plate|downregulation of anterior neural cell fate of the neural plate|down-regulation of anterior neural cell fate of the neural plate|posteriorization|inhibition of anterior neural cell fate of the neural plate Any process that stops, prevents or reduces the frequency or rate at which a cell adopts an anterior neural cell fate. GO:0071053 alpha9-beta1 integrin-ADAM2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071053 ITGA9-ITGB1-ADAM2 complex A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM2. GO:0022002 negative regulation of anterior neural cell fate commitment of the neural plate by Wnt signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022002 Wnt receptor signaling involved in negative regulation of anterior neural cell fate of the neural plate|Wnt receptor signaling involved in inhibition of anterior neural cell fate of the neural plate|Wnt receptor signaling involved in down-regulation of anterior neural cell fate of the neural plate|Wnt receptor signalling involved in negative regulation of anterior neural cell fate of the neural plate|negative regulation of anterior neural cell fate commitment of the neural plate by Wnt-activated signaling pathway|Wnt receptor signaling involved in downregulation of anterior neural cell fate of the neural plate|negative regulation of anterior neural cell fate commitment of the neural plate by Wnt receptor signaling pathway|Wnt receptor signaling involved in down regulation of anterior neural cell fate of the neural plate The series of molecular signals that stops, prevents or reduces the frequency or rate at which a cell adopts an anterior neural cell fate, initiated by binding of Wnt protein to a receptor on the surface of the target cell. GO:0022003 negative regulation of anterior neural cell fate commitment of the neural plate by fibroblast growth factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022003 fgf receptor signaling involved in down-regulation of anterior neural cell fate of the neural plate|fgf receptor signaling involved in inhibition of anterior neural cell fate of the neural plate|fgf receptor signaling involved in down regulation of anterior neural cell fate of the neural plate|fgf receptor signaling involved in negative regulation of anterior neural cell fate of the neural plate|fgf receptor signalling involved in negative regulation of anterior neural cell fate of the neural plate|fgf receptor signaling involved in downregulation of anterior neural cell fate of the neural plate The series of molecular signals that stops, prevents or reduces the frequency or rate at which cell adopts an anterior neural cell fate, generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands. GO:0071050 sno(s)RNA polyadenylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071050 sRNA polyadenylation|snoRNA polyadenylation The enzymatic addition of a sequence of adenylyl residues at the 3' end of snoRNA class molecule (referred to as an sRNA in Archaea). In eukaryotes, this occurs in conjunction with termination of transcription of precursor snoRNA molecules and may occur post-transcriptionally on incorrectly processed molecules targeted for degradation. GO:0022004 midbrain-hindbrain boundary maturation during brain development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022004 A developmental process occurring after the brain has been specified along the neural axis that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate. GO:0071051 polyadenylation-dependent snoRNA 3'-end processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071051 poly(A)-dependent snoRNA 3'-end processing Any process involved in forming the mature 3' end of a snoRNA molecule linked to prior polyadenylation of the 3'-end of the precursor snoRNA. GO:0022005 midbrain-hindbrain boundary maturation during neural plate development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022005 midbrain-hindbrain boundary maturation involved in neural plate development A developmental process occurring before the brain has been specified along the neural axis that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate. GO:0022006 zona limitans intrathalamica formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022006 zli biosynthesis|zli formation The formation of the narrow stripe of cells that lies between the prospective dorsal and ventral thalami. This boundary contains signals that pattern the prethalamic and thalamic territories of the future mid-diencephalon. GO:1901279 D-ribose 5-phosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901279 D-ribose 5-phosphate degradation|D-ribose 5-phosphate catabolism|D-ribose 5-phosphate breakdown The chemical reactions and pathways resulting in the breakdown of D-ribose 5-phosphate. OBO:GOCHE_52217 substance with pharmaceutical role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_52217 GO:1901277 tartrate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901277 tartrate anabolism|tartrate synthesis|tartrate formation|tartrate biosynthesis The chemical reactions and pathways resulting in the formation of tartrate. GO:1901278 D-ribose 5-phosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901278 D-ribose 5-phosphate metabolism The chemical reactions and pathways involving D-ribose 5-phosphate. GO:1901275 tartrate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901275 tartrate metabolism The chemical reactions and pathways involving tartrate. GO:1901276 tartrate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901276 tartrate degradation|tartrate breakdown|tartrate catabolism The chemical reactions and pathways resulting in the breakdown of tartrate. OBO:GOCHE_52214 substance with ligand role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_52214 GO:1901284 5,6,7,8-tetrahydromethanopterin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901284 5,6,7,8-tetrahydromethanopterin degradation|5,6,7,8-tetrahydromethanopterin breakdown|5,6,7,8-tetrahydromethanopterin catabolism The chemical reactions and pathways resulting in the breakdown of 5,6,7,8-tetrahydromethanopterin. GO:1901285 5,6,7,8-tetrahydromethanopterin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901285 5,6,7,8-tetrahydromethanopterin formation|5,6,7,8-tetrahydromethanopterin biosynthesis|5,6,7,8-tetrahydromethanopterin anabolism|5,6,7,8-tetrahydromethanopterin synthesis The chemical reactions and pathways resulting in the formation of 5,6,7,8-tetrahydromethanopterin. GO:1901282 fructoselysine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901282 fructosyllysine anabolism|fructosyllysine biosynthesis|fructosyllysine synthesis|fructosyllysine formation|fructosyllysine biosynthetic process The chemical reactions and pathways resulting in the formation of fructoselysine. GO:1901283 5,6,7,8-tetrahydromethanopterin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901283 5,6,7,8-tetrahydromethanopterin metabolism The chemical reactions and pathways involving 5,6,7,8-tetrahydromethanopterin. GO:1901280 D-ribose 5-phosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901280 D-ribose 5-phosphate biosynthesis|D-ribose 5-phosphate anabolism|D-ribose 5-phosphate synthesis|D-ribose 5-phosphate formation The chemical reactions and pathways resulting in the formation of D-ribose 5-phosphate. GO:1901281 fructoselysine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901281 fructosyllysine catabolism|fructosyllysine catabolic process|fructosyllysine degradation|fructosyllysine breakdown The chemical reactions and pathways resulting in the breakdown of fructoselysine. GO:0022007 convergent extension involved in neural plate elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022007 The process of directed cell movement in the neural plate resulting in tissue elongation via intercalation of adjacent cells in an epithelial sheet at the midline, leading to narrowing and lengthening of the neural plate. GO:0022008 neurogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022008 Wikipedia:Neurogenesis neural cell differentiation|nervous system cell generation Generation of cells within the nervous system. GO:0022009 central nervous system vasculogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022009 The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes in the central nervous system. The capillary endothelial cells in the brain are specialized to form the blood-brain barrier. GO:0071058 alpha3-beta1 integrin-CD151 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071058 ITGA3-ITGB1-CD151 complex A protein complex that consists of an alpha3-beta1 integrin complex bound to the tetraspanin CD151. GO:0071059 alpha6-beta1 integrin-CD151 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071059 ITGA6-ITGB1-CD151 complex A protein complex that consists of an alpha6-beta1 integrin complex bound to the tetraspanin CD151. CHEBI:9036 sarpagine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_9036 GO:0071056 alpha9-beta1 integrin-ADAM15 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071056 ITGA9-ITGB1-ADAM15 complex A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM15. GO:0071057 alphav-beta3 integrin-ADAM15 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071057 ITGAV-ITGB3-ADAM15 complex A protein complex that consists of an alphav-beta3 integrin complex bound to the transmembrane metallopeptidase ADAM15. CHEBI:9096 L-selenohomocysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_9096 CHEBI:75558 2-oleoyl-3-stearoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75558 CHEBI:9093 selenocysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_9093 GO:0061600 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0061600 GO:0061601 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0061601 GO:0061602 molybdenum cofactor cytidylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061602 RHEA:31335|EC:2.7.7.76 Catalysis of the reaction CTP + molybdenum cofactor = diphosphate + cytidylyl molybdenum cofactor. GO:0061603 molybdenum cofactor guanylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061603 RHEA:34243|EC:2.7.7.77 Catalysis of the reaction GTP + molybdenum cofactor = diphosphate + guanylyl molybdenum cofactor. GO:0061604 molybdopterin-synthase sulfurtransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061604 RHEA:48612|EC:2.8.1.11 Catalysis of the reaction: [Molybdopterin-synthase sulfur-carrier protein]-Gly-Gly-AMP + [cysteine desulfurase]-S-sulfanyl-L-cysteine <=> AMP [molybdopterin-synthase sulfur-carrier protein]-Gly-NH-CH(2)-C(O)SH + cysteine desulfurase. CHEBI:75550 1-stearoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75550 GO:0061605 molybdopterin-synthase adenylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061605 EC:2.7.7.80|RHEA:43616 Catalysis of the reaction: ATP [molybdopterin-synthase sulfur-carrier protein]-Gly-Gly = diphosphate [molybdopterin-synthase sulfur-carrier protein]-Gly-Gly-AMP. GO:0061606 N-terminal protein amino acid propionylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061606 The propionylation of the N-terminal amino acid of proteins. GO:0061607 peptide alpha-N-propionyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061607 N-terminal propionyltransferase activity Catalysis of the reaction: propionyl-CoA + peptide = CoA + N-alpha-propionylpeptide. This reaction is the propionylation of the N-terminal amino acid residue of a peptide or protein. GO:0061608 nuclear import signal receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061608 importin activity Combining with a nuclear import signal (NIS) on a cargo to be transported, to mediate transport of the cargo through the nuclear pore, from the cytoplasm to the nuclear lumen. The cargo can be either a RNA or a protein. GO:0061609 fructose-1-phosphate aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061609 Reactome:R-HSA-70342|RHEA:30851|Reactome:R-HSA-5656438 Catalysis of the reaction: D-fructose-1-phosphate = dihydroxyacetone phosphate + D-glyceraldehyde. CHEBI:75555 1-monostearoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75555 CHEBI:75553 3-stearoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75553 CHEBI:75569 3-linoleoyl-2-oleoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75569 CHEBI:75568 1-monolinolein biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75568 CHEBI:75561 1-linoleoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75561 CHEBI:75562 1-monomyristoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75562 CHEBI:75563 3-linoleoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75563 CHEBI:75579 1-lauroyl-2-oleoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75579 GO:0061620 glycolytic process through glucose-6-phosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061620 MetaCyc:GLYCOLYSIS The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, occurring through a glucose-6-phosphate intermediate, with the concomitant production of a small amount of ATP. GO:0061621 canonical glycolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061621 Reactome:R-HSA-70171|MetaCyc:PWY66-400|MetaCyc:ANAGLYCOLYSIS-PWY|Wikipedia:Glycolysis The glycolytic process that begins with the conversion of glucose to glucose-6-phosphate by glucokinase activity. Glycolytic processes are the chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP. GO:0061622 glycolytic process through glucose-1-phosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061622 The chemical reactions and pathways through a glucose-1-phosphate intermediate that result in the catabolism of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP. GO:0061623 glycolytic process from galactose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061623 The chemical reactions and pathways resulting in the breakdown of galactose into pyruvate, with the concomitant production of a small amount of ATP. GO:0061624 fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061624 The chemical reactions and pathways resulting in the breakdown of fructose that results in the formation of dihydroxyacetone phosphate and glyceraldehyde-3-phosphate. GO:0061625 glycolytic process through fructose-1-phosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061625 The chemical reactions and pathways resulting in the breakdown of fructose into pyruvate through a fructose-1-phosphate intermediate, with the concomitant production of ATP and NADH. GO:0061626 pharyngeal arch artery morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061626 aortic arch artery morphogenesis The process in which the anatomical structures of a pharyngeal arch artery is generated and organized. The pharyngeal arch arteries are a series of six paired embryological vascular structures, the development of which give rise to several major arteries, such as the stapedial artery, the middle meningeal artery, the internal carotid artery and the pulmonary artery. GO:0061627 S-methylmethionine-homocysteine S-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061627 RHEA:26337|Reactome:R-HSA-5696838 homocysteine methyltransferase activity|S-methylmethionine homocysteine transmethylase activity|homocysteine transmethylase activity|methylmethionine:homocysteine methyltransferase activity Catalysis of the reaction: S-methyl-L-methionine + L-homocysteine = 2 L-methionine + H+. CHEBI:75573 2-oleoyl-3-arachidonoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75573 GO:0061628 H3K27me3 modified histone binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061628 H3-K27me3 modified histone binding Interacting selectively and non-covalently with a histone H3 in which the lysine residue at position 27 has been modified by trimethylation. CHEBI:75571 3-arachidonoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75571 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding|RNA polymerase II sequence-specific DNA-binding transcription factor binding Interacting selectively and non-covalently with a sequence-specific DNA binding RNA polymerase II transcription factor, any of the factors that interact selectively and non-covalently with a specific DNA sequence in order to modulate transcription. CHEBI:9068 Se-methylselenocysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_9068 GO:0061610 glycerol to glycerone phosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061610 glycerol to dihydroxyacetone phosphate metabolic process|glycerol metabolism to DHAP|glycerol metabolism to dihydroxyacetone phosphate|glycerol to DHAP metabolic process|glycerol metabolism to glycerone phosphate The chemical reactions and pathways in which glycerol, 1,2,3-propanetriol, is converted to glycerone phosphate. GO:0061611 mannose to fructose-6-phosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061611 mannose metabolism to fructose-6-phosphate The chemical reactions and pathways in which mannose, the aldohexose manno-hexose, is converted to fructose-6-phosphate. GO:0061612 galactose to glucose-1-phosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061612 The chemical reactions and pathways in which galactose, the aldohexose galacto-hexose, is converted to glucose-1-phosphate. GO:0061613 glycolytic process from glycerol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061613 The glycolytic process in which glycerol is catabolized to pyruvate generating ATP and NADH. GO:0061614 pri-miRNA transcription by RNA polymerase II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061614 pri-miRNA transcription from RNA polymerase II promoter The cellular synthesis of primary microRNA (pri-miRNA) transcripts from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter. pri-miRNA transcripts are subsequently processed to produce the ~22nt miRNAs that function in gene regulation. GO:0061615 glycolytic process through fructose-6-phosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061615 MetaCyc:PWY-5484 glycolysis through fructose-6-phosphate The chemical reactions and pathways resulting in the breakdown of a monosaccharide into pyruvate, occurring through a fructose-6-phosphate intermediate, with the concomitant production of ATP and NADH. CHEBI:75583 1,2-dioleoyl-3-palmitoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75583 GO:0061616 glycolytic process from fructose through fructose-6-phosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061616 MetaCyc:PWY-5484 glycolysis from fructose through fructose-6-phosphate The glycolytic process through fructose-6-phosphate in which fructose is catabolized into pyruvate. CHEBI:75584 palmityl palmitate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75584 GO:0061617 MICOS complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061617 MitOS complex|MINOS complex|mitochondrial contact site and cristae organizing system|Fcj1 complex Mitochondrial inner membrane complex involved in maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. In Saccharomyces cerevisiae the complex has six subunits: MIC10, MIC12, MIC19, MIC26, MIC27, and MIC60. CHEBI:75582 1-myristoyl-2-oleoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75582 GO:0061618 obsolete sublamina densa biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061618 OBSOLETE. The part of the basement membrane that lies beneath the lamina densa, containing anchoring fibrils, anchoring plaques, collagen fibers, and elastic fibers. CHEBI:75587 2-hydroxypalmityl palmitate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75587 GO:0061619 glycolytic process from mannose through fructose-6-phosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061619 The chemical reactions and pathways resulting in the breakdown of mannose into pyruvate, occurring through a fructose-6-phosphate intermediate, with the concomitant production of ATP and NADH. CHEBI:75585 1-palmitoyl-2-oleoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75585 CHEBI:75586 1,2-hexadecanediol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75586 GO:0046000 positive regulation of ecdysteroid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046000 up regulation of ecdysteroid secretion|activation of ecdysteroid secretion|stimulation of ecdysteroid secretion|up-regulation of ecdysteroid secretion|upregulation of ecdysteroid secretion Any process that activates or increases the frequency, rate or extent of the regulated release of ecdysteroid. GO:0046007 negative regulation of activated T cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046007 negative regulation of activated T-lymphocyte proliferation|down-regulation of activated T cell proliferation|negative regulation of activated T lymphocyte proliferation|downregulation of activated T cell proliferation|down regulation of activated T cell proliferation|inhibition of activated T cell proliferation|negative regulation of activated T-cell proliferation Any process that stops, prevents or reduces the rate or extent of activated T cell proliferation. GO:0046008 regulation of female receptivity, post-mating biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046008 Any process that modulates the receptiveness of a female to male advances subsequent to mating. GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046005 up-regulation of circadian sleep/wake cycle, REM sleep|upregulation of circadian sleep/wake cycle, REM sleep|up regulation of circadian sleep/wake cycle, REM sleep|activation of circadian sleep/wake cycle, REM sleep|stimulation of circadian sleep/wake cycle, REM sleep|positive regulation of REM sleep Any process that activates or increases the duration or quality of rapid eye movement (REM) sleep. GO:0046006 regulation of activated T cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046006 regulation of activated T-cell proliferation|regulation of activated T-lymphocyte proliferation|regulation of activated T lymphocyte proliferation Any process that modulates the frequency, rate or extent of activated T cell proliferation. GO:0046003 negative regulation of syncytial blastoderm mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046003 negative regulation of syncytial blastoderm cell cycle progression|down regulation of progression through syncytial blastoderm mitotic cell cycle|negative regulation of progression through syncytial blastoderm mitotic cell cycle|downregulation of progression through syncytial blastoderm mitotic cell cycle|down-regulation of progression through syncytial blastoderm mitotic cell cycle|inhibition of progression through syncytial blastoderm mitotic cell cycle Any process that stops, prevents or reduces the rate or extent of progression through the syncytial blastoderm mitotic cell cycle. GO:0046004 positive regulation of syncytial blastoderm mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046004 upregulation of progression through syncytial blastoderm mitotic cell cycle|positive regulation of progression through syncytial blastoderm mitotic cell cycle|up regulation of progression through syncytial blastoderm mitotic cell cycle|activation of progression through syncytial blastoderm mitotic cell cycle|stimulation of progression through syncytial blastoderm mitotic cell cycle|up-regulation of progression through syncytial blastoderm mitotic cell cycle|positive regulation of syncytial blastoderm cell cycle progression Any process that activates or increases the rate or extent of progression through the syncytial blastoderm mitotic cell cycle. GO:0046001 negative regulation of preblastoderm mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046001 downregulation of progression through preblastoderm mitotic cell cycle|down regulation of progression through preblastoderm mitotic cell cycle|inhibition of progression through preblastoderm mitotic cell cycle|negative regulation of progression through preblastoderm mitotic cell cycle|down-regulation of progression through preblastoderm mitotic cell cycle|negative regulation of preblastoderm mitotic cell cycle progression Any process that stops, prevents or reduces the rate or extent of progression through the preblastoderm mitotic cell cycle. GO:0046002 positive regulation of preblastoderm mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046002 positive regulation of preblastoderm mitotic cell cycle progression|upregulation of progression through preblastoderm mitotic cell cycle|stimulation of progression through preblastoderm mitotic cell cycle|positive regulation of progression through preblastoderm mitotic cell cycle|up-regulation of progression through preblastoderm mitotic cell cycle|activation of progression through preblastoderm mitotic cell cycle|up regulation of progression through preblastoderm mitotic cell cycle Any process that activates or increases the rate or extent of progression through the preblastoderm mitotic cell cycle. GO:0061640 cytoskeleton-dependent cytokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061640 A cytokinesis that involves the function of a set of proteins that are part of the microfilament or microtubule cytoskeleton. GO:0061641 CENP-A containing chromatin organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061641 centromeric chromatin organization Any process that results in the specification, formation or maintenance of the physical structure of CENP-A containing chromatin. GO:0061642 chemoattraction of axon biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061642 The process in which a neuron growth cone is directed to a specific target site in response to an attractive chemical signal. GO:0061643 chemorepulsion of axon biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061643 The process in which a neuron growth cone is directed to a specific target site in response to a repulsive chemical cue. GO:0061644 protein localization to CENP-A containing chromatin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061644 Any process in which a protein is transported to, or maintained at, CENP-A containing chromatin. CHEBI:75590 1-stearoyl-2-oleoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75590 GO:0061645 endocytic patch biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061645 The part of the cell cortex consisting of an aggregation of proteins that will give rise to an endocytic vesicle. CHEBI:75591 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75591 GO:0061646 positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061646 Any process that activates or increases the frequency, rate or extent of glutamate secretion in response to membrane depolarization, where glutamate acts as a neurotransmitter. GO:0046009 positive regulation of female receptivity, post-mating biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046009 up regulation of female receptivity, post-mating|activation of female receptivity, post-mating|stimulation of female receptivity, post-mating|up-regulation of female receptivity, post-mating|upregulation of female receptivity, post-mating Any process that increases the receptiveness of a female to male advances subsequent to mating. GO:0061647 histone H3-K9 modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061647 The modification of histone H3 at a lysine in position 9 of the histone. GO:0061648 tooth replacement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061648 The process whose specific outcome is the replacement of an existing tooth with another tooth. GO:0061649 ubiquitin modification-dependent histone binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061649 ubiquitinated histone binding Interacting selectively and non-covalently with a histone protein in which a residue has been modified by ubiquitination. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. CHEBI:75592 L-cycloserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75592 CHEBI:75596 EC 5.* (isomerase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75596 GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046010 activation of circadian sleep/wake cycle, non-REM sleep|stimulation of circadian sleep/wake cycle, non-REM sleep|positive regulation of non-REM sleep|up-regulation of circadian sleep/wake cycle, non-REM sleep|upregulation of circadian sleep/wake cycle, non-REM sleep|up regulation of circadian sleep/wake cycle, non-REM sleep Any process that activates or increases the duration or quality of non-rapid eye movement (NREM) sleep. GO:0046011 regulation of oskar mRNA translation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046011 Any process that modulates the frequency, rate or extent of oskar mRNA translation. To ensure the localization of Oskar protein at the posterior pole of the oocyte, translation of oskar mRNA is repressed during its transport to the posterior pole and activated upon localization of the mRNA at the posterior cortex. GO:0046018 obsolete positive regulation of transcription from RNA polymerase I promoter during mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046018 up-regulation of transcription from RNA polymerase I promoter during mitosis|mitotic activation of transcription from Pol I promoter|positive regulation of transcription from Pol I promoter during mitosis|upregulation of transcription from RNA polymerase I promoter during mitosis|up regulation of transcription from RNA polymerase I promoter during mitosis|activation of transcription from RNA polymerase I promoter during mitosis|stimulation of transcription from RNA polymerase I promoter during mitosis|positive regulation of transcription from RNA polymerase I promoter, mitotic OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase I promoter that occurs during the mitotic cell cycle. GO:0046019 regulation of transcription from RNA polymerase II promoter by pheromones biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046019 regulation of transcription from Pol II promoter by pheromones Any process involving pheromones that modulates the frequency, rate or extent or transcription from an RNA polymerase II promoter. GO:0046016 positive regulation of transcription by glucose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046016 upregulation of transcription by glucose|stimulation of transcription by glucose|up-regulation of transcription by glucose|activation of transcription by glucose|up regulation of transcription by glucose Any process involving glucose that activates or increases the rate of transcription. GO:0046017 obsolete regulation of transcription from RNA polymerase I promoter during mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046017 regulation of transcription from Pol I promoter during mitosis|regulation of transcription from RNA polymerase I promoter during mitosis|mitotic regulation of transcription from Pol I promoter OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of transcription from an RNA polymerase I promoter that occurs during the mitotic cell cycle. GO:0046014 negative regulation of T cell homeostatic proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046014 negative regulation of T-lymphocyte homeostatic proliferation|down-regulation of T cell homeostatic proliferation|negative regulation of T lymphocyte homeostatic proliferation|downregulation of T cell homeostatic proliferation|negative regulation of resting T cell proliferation|down regulation of T cell homeostatic proliferation|inhibition of T cell homeostatic proliferation|negative regulation of T-cell homeostatic proliferation Any process that stops, prevents or reduces the rate or extent of resting T cell proliferation. GO:0046015 regulation of transcription by glucose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046015 Any process involving glucose that modulates the frequency, rate or extent or transcription. GO:0046012 positive regulation of oskar mRNA translation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046012 upregulation of oskar mRNA translation|stimulation of oskar mRNA translation|activation of oskar mRNA translation|up-regulation of oskar mRNA translation|up regulation of oskar mRNA translation Any process that activates or increases the frequency, rate or extent of oskar mRNA translation. GO:0046013 regulation of T cell homeostatic proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046013 regulation of resting T cell proliferation|regulation of T-cell homeostatic proliferation|regulation of T-lymphocyte homeostatic proliferation|regulation of T lymphocyte homeostatic proliferation Any process that modulates the frequency, rate or extent of resting T cell proliferation. GO:0061630 ubiquitin protein ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061630 Reactome:R-HSA-8939706|Reactome:R-HSA-6781867|Reactome:R-HSA-5654679|Reactome:R-HSA-9009308|Reactome:R-HSA-5687081|Reactome:R-HSA-5654677|Reactome:R-HSA-8866546|Reactome:R-HSA-201445|Reactome:R-HSA-8956684|Reactome:R-HSA-5690827|Reactome:R-HSA-8848829|Reactome:R-HSA-8877003|Reactome:R-HSA-3322429|Reactome:R-HSA-6782943|Reactome:R-HSA-936475|Reactome:R-HSA-9009403|Reactome:R-HSA-8875431|Reactome:R-HSA-5246693|Reactome:R-HSA-8939335|Reactome:R-HSA-1504190|Reactome:R-HSA-5654672|Reactome:R-HSA-8876258|Reactome:R-HSA-9011300|Reactome:R-HSA-990526|Reactome:R-HSA-8952382|Reactome:R-HSA-9686969|Reactome:R-HSA-8854628|Reactome:R-HSA-5654684|Reactome:R-HSA-8854051|Reactome:R-HSA-6804253|Reactome:R-HSA-6804879|Reactome:R-HSA-1225956|Reactome:R-HSA-934604|Reactome:R-HSA-3640861|Reactome:R-HSA-69015|Reactome:R-HSA-68946|Reactome:R-HSA-6804942|Reactome:R-HSA-8875183|Reactome:R-HSA-8938773|Reactome:R-HSA-5635864|Reactome:R-HSA-9008076|Reactome:R-HSA-5689111|Reactome:R-HSA-8943080|Reactome:R-HSA-8866856|Reactome:R-HSA-6804724|Reactome:R-HSA-5610737|Reactome:R-HSA-5684071|Reactome:R-HSA-6785361|Reactome:R-HSA-8943003|Reactome:R-HSA-6807106|Reactome:R-HSA-5635856|Reactome:R-HSA-5658424|Reactome:R-HSA-8956026|Reactome:R-HSA-8943040|Reactome:R-HSA-8948775|Reactome:R-HSA-6790487|Reactome:R-HSA-8953946|Reactome:R-HSA-6798373|Reactome:R-HSA-4641129|Reactome:R-HSA-5632648|Reactome:R-HSA-4641253|Reactome:R-HSA-9706354|Reactome:R-HSA-8952419|Reactome:R-HSA-6804441|Reactome:R-HSA-8948832|Reactome:R-HSA-8854041|Reactome:R-HSA-5682858|Reactome:R-HSA-9686920|Reactome:R-HSA-9604629|Reactome:R-HSA-4641246|Reactome:R-HSA-9706356|Reactome:R-HSA-4608852|Reactome:R-HSA-9021523|Reactome:R-HSA-9033485|Reactome:R-HSA-8867288|Reactome:R-HSA-8942101|Reactome:R-HSA-6807134|Reactome:R-HSA-4641159|Reactome:R-HSA-8851011|Reactome:R-HSA-936462|Reactome:R-HSA-8938815|Reactome:R-HSA-5674022|Reactome:R-HSA-9008479 E3 involved in endoplasmic reticulum-associated degradation|ubiquitin-protein ligase activity involved in positive regulation of mitotic metaphase/anaphase transition|ubiquitin protein ligase activity involved in chloroplast disassembly|APC-Cdc20 complex activity|APC-fizzy related complex activity|ER-associated E3 ligase|ubiquitin ligase activity|ubiquitin protein ligase activity involved in ERAD pathway|ubiquitin protein ligase activity involved in ER-associated degradation pathway|protein ubiquitination activity|ubiquitin ligase activity involved in ER-associated degradation pathway|E3 Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues. GO:0061631 ubiquitin conjugating enzyme activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061631 EC:2.3.2.23 HECT E3|E2 Isoenergetic transfer of ubiquitin from one protein to another via the reaction X-ubiquitin + Y -> Y-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue. GO:0061632 RNA lariat debranching enzyme activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061632 Increases the activity of an enzyme that catalyzes the hydrolysis of branched RNA structures that contain vicinal 2'-5'- and 3'-5'-phosphodiester bonds at a branch point nucleotide. GO:0061633 transport-coupled glycolytic process through glucose-6-phosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061633 The chemical reactions and pathways resulting in the breakdown of glucose into pyruvate, in which the glucose is converted to glucose-6-phosphate intermediate coupled to transmembrane transport. GO:0061634 alpha-D-xyloside xylohydrolase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061634 EC:3.2.1.177 alpha-xylosidase Catalysis of the hydrolysis of terminal, non-reducing alpha-D-xylose residues with release of alpha-D-xylose. GO:0061635 regulation of protein complex stability biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061635 Any process that affects the structure and integrity of a protein complex by altering the likelihood of its assembly or disassembly. GO:0061636 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0061636 GO:0061637 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0061637 GO:0061638 CENP-A containing chromatin biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061638 centromeric core region chromatin|chromatin containing CENP-A|nuclear CENP-A containing chromatin|centromeric core domain chromatin The specialized chromatin located in the centromeric core region or the entire centromeric region in organisms with point centromeres, which is enriched for CENP-A-containing nucleosomes. This chromatin forms a 3-dimensional structure which provides a platform for kinetochore assembly and microtubule attachment. GO:0061639 Cdv-dependent cytokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061639 A cytokinesis that involves a set of conserved proteins including the Cdv proteins, and results in the formation of two similarly sized and shaped cells. GO:0046021 obsolete regulation of transcription from RNA polymerase II promoter during mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046021 regulation of transcription from RNA polymerase II promoter during mitosis|regulation of transcription from Pol II promoter, mitotic|mitotic regulation of transcription from Pol II promoter OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that occurs during the mitotic cell cycle. GO:0046022 obsolete positive regulation of transcription from RNA polymerase II promoter during mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046022 up regulation of transcription from RNA polymerase II promoter during mitosis|positive regulation of transcription from RNA polymerase II promoter, mitotic|mitotic activation of transcription from Pol II promoter|upregulation of transcription from RNA polymerase II promoter during mitosis|positive regulation of transcription from Pol II promoter during mitosis|stimulation of transcription from RNA polymerase II promoter during mitosis|up-regulation of transcription from RNA polymerase II promoter during mitosis|activation of transcription from RNA polymerase II promoter during mitosis OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter that occurs during the mitotic cell cycle. GO:0046020 negative regulation of transcription from RNA polymerase II promoter by pheromones biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046020 down regulation of transcription from RNA polymerase II promoter by pheromones|downregulation of transcription from RNA polymerase II promoter by pheromones|down-regulation of transcription from RNA polymerase II promoter by pheromones|inhibition of transcription from RNA polymerase II promoter by pheromones|negative regulation of transcription from Pol II promoter by pheromones Any process involving pheromones that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter. GO:0046029 mannitol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046029 RHEA:15029|KEGG_REACTION:R07135|MetaCyc:1.1.1.255-RXN|EC:1.1.1.255 NAD-dependent mannitol dehydrogenase activity|mannitol:NAD+ 1-oxidoreductase activity|MTD activity Catalysis of the reaction: D-mannitol + NAD(+) = D-mannose + H(+) + NADH. GO:0046027 phospholipid:diacylglycerol acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046027 MetaCyc:2.3.1.158-RXN|RHEA:14057|EC:2.3.1.158 phospholipid:1,2-diacyl-sn-glycerol O-acyltransferase activity|PDAT activity Catalysis of the reaction: phospholipid + 1,2-diacylglycerol = lysophospholipid + triacylglycerol. GO:0046028 electron transporter, transferring electrons from cytochrome b6/f complex of photosystem II activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046028 plastocyanin Enables the directed movement of electrons from the cytochrome b6/f complex of photosystem II. GO:0046025 precorrin-6Y C5,15-methyltransferase (decarboxylating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046025 RHEA:17477|MetaCyc:2.1.1.132-RXN|EC:2.1.1.132 precorrin-6Y methylase activity|S-adenosyl-L-methionine:1-precorrin-6Y C5,15-methyltransferase (C-12-decarboxylating)|precorrin-6 methyltransferase activity Catalysis of the reaction: 2 S-adenosyl-L-methionine + precorrin-6Y = 2 S-adenosyl-L-homocysteine + precorrin-8X + CO2. GO:0046026 precorrin-4 C11-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046026 RHEA:22012|MetaCyc:2.1.1.133-RXN|EC:2.1.1.133 CobM|S-adenosyl-L-methionine:precorrin-4 C11 methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + precorrin-4 = S-adenosyl-L-homocysteine + precorrin 5. GO:0061660 Atg12 ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061660 E3 Catalysis of the transfer of Atg12 to a substrate protein via the reaction X-Atg12 + S --> X + S-Atg12, where X is either an E2 or E3 enzyme, the X-Atg12 linkage is a thioester bond, and the S-Atg12 linkage is an isopeptide bond between the C-terminal amino acid of Atg12 and the epsilon-amino group of lysine residues in the substrate. GO:0046023 obsolete regulation of transcription from RNA polymerase III promoter during mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046023 mitotic regulation of transcription from Pol III promoter|regulation of transcription from RNA polymerase III promoter during mitosis|regulation of transcription from Pol III promoter, mitotic OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of transcription from an RNA polymerase III promoter that occurs during the mitotic cell cycle. GO:0046024 obsolete positive regulation of transcription from RNA polymerase III promoter during mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046024 up regulation of transcription from RNA polymerase III promoter during mitosis|activation of transcription from RNA polymerase III promoter during mitosis|stimulation of transcription from RNA polymerase III promoter during mitosis|positive regulation of transcription from RNA polymerase III promoter, mitotic|up-regulation of transcription from RNA polymerase III promoter during mitosis|mitotic activation of transcription from Pol III promoter|positive regulation of transcription from Pol III promoter during mitosis|upregulation of transcription from RNA polymerase III promoter during mitosis OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase III that occurs during the mitotic cell cycle. GO:0061661 FAT10 ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061661 E3 Catalysis of the transfer of FAT10 to a substrate protein via the reaction X-FAT10 + S --> X + S-FAT10, where X is either an E2 or E3 enzyme, the X-FAT10 linkage is a thioester bond, and the S-FAT10 linkage is an isopeptide bond between the C-terminal glycine of FAT10 and the epsilon-amino group of lysine residues in the substrate. GO:0061662 ISG15 ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061662 E3 Catalysis of the transfer of a ISG15 to a substrate protein via the reaction X-ISG15 + S --> X + S-ISG15, where X is either an E2 or E3 enzyme, the X-ISG15 linkage is a thioester bond, and the S-ISG15 linkage is an isopeptide bond between the C-terminal amino acid of ISG15 and the epsilon-amino group of lysine residues in the substrate. GO:0061663 NEDD8 ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061663 E3 Catalysis of the transfer of NEDD8 to a substrate protein via the reaction X-NEDD8 + S --> X + S-NEDD8, where X is either an E2 or E3 enzyme, the X-NEDD8 linkage is a thioester bond, and the S-NEDD8 linkage is an isopeptide bond between the C-terminal amino acid of NEDD8 and the epsilon-amino group of lysine residues in the substrate. GO:0061664 Pup ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061664 E3 Catalysis of the transfer of Pup to a substrate protein via the reaction X-Pup + S --> X + S-Pup, where X is either an E2 or E3 enzyme, the X-Pup linkage is a thioester bond, and the S-Pup linkage is an isopeptide bond between the C-terminal amino acid of Pup and the epsilon-amino group of lysine residues in the substrate. GO:0061665 SUMO ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061665 E3 Catalysis of the transfer of SUMO to a substrate protein via the reaction X-SUMO + S --> X + S-SUMO, where X is either an E2 or E3 enzyme, the X-SUMO linkage is a thioester bond, and the S-SUMO linkage is an isopeptide bond between the C-terminal amino acid of SUMO and the epsilon-amino group of lysine residues in the substrate. GO:0061666 UFM1 ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061666 E3 Catalysis of the transfer of UFM1 to a substrate protein via the reaction X-UFM1 + S --> X + S-UFM1, where X is either an E2 or E3 enzyme, the X-UFM1 linkage is a thioester bond, and the S-UFM1 linkage is an isopeptide bond between the C-terminal amino acid of UFM1 and the epsilon-amino group of lysine residues in the substrate. GO:0061667 URM1 ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061667 E3 Catalysis of the transfer of URM1 to a substrate protein via the reaction X-URM1 + S --> X + S-URM1, where X is either an E2 or E3 enzyme, the X-URM1 linkage is a thioester bond, and the S-URM1 linkage is an isopeptide bond between the C-terminal amino acid of URM1 and the epsilon-amino group of lysine residues in the substrate. GO:0061668 mitochondrial ribosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061668 The aggregation, arrangement and bonding together of the mitochondrial ribosome and of its subunits. GO:0061669 spontaneous neurotransmitter secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061669 stimulus-independent neurotransmitter secretion Neurotransmitter secretion that occurs in the absence of the action of a secretagogue or a presynaptic action potential. GO:0046032 ADP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046032 ADP degradation|ADP breakdown|ADP catabolism The chemical reactions and pathways resulting in the breakdown of ADP, adenosine 5'-diphosphate. GO:0046033 AMP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046033 adenylate forming enzyme activity|AMP metabolism The chemical reactions and pathways involving AMP, adenosine monophosphate. GO:0046030 inositol trisphosphate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046030 IP3 phosphatase activity|IP(3) phosphatase activity|inositol-1,4,5-trisphosphate phosphatase Catalysis of the reaction: myo-inositol trisphosphate + H2O = myo-inositol bisphosphate + phosphate. GO:0046031 ADP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046031 ADP metabolism The chemical reactions and pathways involving ADP, adenosine 5'-diphosphate. GO:0046038 GMP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046038 GMP degradation|GMP breakdown|GMP catabolism The chemical reactions and pathways resulting in the breakdown of GMP, guanosine monophosphate. GO:0046039 GTP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046039 GTP metabolism The chemical reactions and pathways involving GTP, guanosine triphosphate. GO:0046036 CTP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046036 CTP metabolism|CTP deamination The chemical reactions and pathways involving CTP, cytidine triphosphate. GO:0046037 GMP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046037 GMP metabolism The chemical reactions and pathways involving GMP, guanosine monophosphate. GO:0046034 ATP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046034 ATP metabolism The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator. GO:0046035 CMP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046035 CMP metabolism The chemical reactions and pathways involving CMP, cytidine monophosphate. GO:0061650 ubiquitin-like protein conjugating enzyme activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061650 E2|small conjugating protein conjugating enzyme activity Isoenergetic transfer of a ubiquitin-like protein (ULP) from one protein to another via the reaction X-SCP + Y -> Y-SCP + X, where both the X-SCP and Y-SCP linkages are thioester bonds between the C-terminal amino acid of SCP and a sulfhydryl side group of a cysteine residue. GO:0061651 Atg12 conjugating enzyme activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061651 E2 Isoenergetic transfer of Atg12 from one protein to another via the reaction X-Atg12 + Y -> Y-Atg12 + X, where both the X-Atg12 and Y-Atg12 linkages are thioester bonds between the C-terminal amino acid of Atg12 and a sulfhydryl side group of a cysteine residue. GO:0061652 FAT10 conjugating enzyme activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061652 E2 Isoenergetic transfer of FAT10 from one protein to another via the reaction X-FAT10 + Y -> Y-FAT10 + X, where both the X-FAT10 and Y-FAT10 linkages are thioester bonds between the C-terminal amino acid of FAT10 and a sulfhydryl side group of a cysteine residue. GO:0061653 ISG15 conjugating enzyme activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061653 E2 Isoenergetic transfer of ISG15 from one protein to another via the reaction X-ISG15 + Y -> Y-ISG15 + X, where both the X-ISG15 and Y-ISG15 linkages are thioester bonds between the C-terminal amino acid of ISG15 and a sulfhydryl side group of a cysteine residue. GO:0061654 NEDD8 conjugating enzyme activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061654 E2 Isoenergetic transfer of NEDD8 from one protein to another via the reaction X-NEDD8 + Y -> Y-NEDD8 + X, where both the X-NEDD8 and Y-NEDD8 linkages are thioester bonds between the C-terminal amino acid of NEDD8 and a sulfhydryl side group of a cysteine residue. GO:0061655 Pup conjugating enzyme activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061655 E2 Isoenergetic transfer of Pup from one protein to another via the reaction X-Pup + Y -> Y-Pup + X, where both the X-Pup and Y-Pup linkages are thioester bonds between the C-terminal amino acid of Pup and a sulfhydryl side group of a cysteine residue. GO:0061656 SUMO conjugating enzyme activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061656 E2 Isoenergetic transfer of SUMO from one protein to another via the reaction X-SUMO + Y -> Y-SUMO + X, where both the X-SUMO and Y-SUMO linkages are thioester bonds between the C-terminal amino acid of SUMO and a sulfhydryl side group of a cysteine residue. GO:0061657 UFM1 conjugating enzyme activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061657 E2 Isoenergetic transfer of UFM1 from one protein to another via the reaction X-UFM1 + Y -> Y-UFM1 + X, where both the X-UFM1 and Y-UFM1 linkages are thioester bonds between the C-terminal amino acid of UFM1 and a sulfhydryl side group of a cysteine residue. GO:0061658 URM1 conjugating enzyme activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061658 E2 Isoenergetic transfer of URM1 from one protein to another via the reaction X-URM1 + Y -> Y-URM1 + X, where both the X-URM1 and Y-URM1 linkages are thioester bonds between the C-terminal amino acid of URM1 and a sulfhydryl side group of a cysteine residue. GO:0061659 ubiquitin-like protein ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061659 small conjugating protein ligase activity|E3 Catalysis of the transfer of a ubiquitin-like protein (ULP) to a substrate protein via the reaction X-ULP + S --> X + S-ULP, where X is either an E2 or E3 enzyme, the X-ULP linkage is a thioester bond, and the S-ULP linkage is an isopeptide bond between the C-terminal glycine of ULP and the epsilon-amino group of lysine residues in the substrate. GO:1905130 carcinine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905130 The directed movement of carcinine from outside of a cell, across the plasma membrane and into the cytosol. GO:1905131 carcinine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1905131 Enables the transfer of carcinine from one side of a membrane to the other. GO:1905132 regulation of meiotic chromosome separation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905132 regulation of chromosome separation during meiosis|regulation of meiotic chromosome resolution Any process that modulates the frequency, rate or extent of meiotic chromosome separation. GO:1905133 negative regulation of meiotic chromosome separation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905133 down-regulation of meiotic chromosome resolution|negative regulation of meiotic chromosome resolution|down regulation of chromosome separation during meiosis|inhibition of chromosome separation during meiosis|down-regulation of meiotic chromosome separation|inhibition of meiotic chromosome resolution|inhibition of meiotic chromosome separation|down regulation of meiotic chromosome resolution|negative regulation of chromosome separation during meiosis|down-regulation of chromosome separation during meiosis|downregulation of meiotic chromosome resolution|down regulation of meiotic chromosome separation|downregulation of meiotic chromosome separation|downregulation of chromosome separation during meiosis Any process that stops, prevents or reduces the frequency, rate or extent of meiotic chromosome separation. GO:1905134 positive regulation of meiotic chromosome separation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905134 up regulation of meiotic chromosome separation|activation of meiotic chromosome separation|upregulation of chromosome separation during meiosis|up-regulation of meiotic chromosome resolution|up-regulation of meiotic chromosome separation|up-regulation of chromosome separation during meiosis|activation of chromosome separation during meiosis|upregulation of meiotic chromosome resolution|upregulation of meiotic chromosome separation|positive regulation of chromosome separation during meiosis|up regulation of meiotic chromosome resolution|positive regulation of meiotic chromosome resolution|up regulation of chromosome separation during meiosis|activation of meiotic chromosome resolution Any process that activates or increases the frequency, rate or extent of meiotic chromosome separation. GO:1905135 biotin import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905135 biotin import into cell|biotin import The directed movement of biotin from outside of a cell, across the plasma membrane and into the cytosol. GO:1905125 positive regulation of glucosylceramidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905125 upregulation of D-glucosyl-N-acylsphingosine glucohydrolase activity|positive regulation of beta-glucocerebrosidase activity|upregulation of glucosylcerebrosidase activity|upregulation of glucosylsphingosine beta-glucosidase activity|up-regulation of glucocerebrosidase activity|up regulation of beta-glucocerebrosidase activity|up regulation of glucosylsphingosine beta-D-glucosidase activity|activation of glucosylsphingosine beta-D-glucosidase activity|upregulation of acid beta-glucosidase activity|activation of GlcCer-beta-glucosidase activity|up-regulation of GlcCer-beta-glucosidase activity|positive regulation of glucosylsphingosine beta-D-glucosidase activity|up-regulation of glucosphingosine glucosylhydrolase activity|positive regulation of GCase activity|upregulation of ceramide glucosidase activity|up-regulation of psychosine hydrolase activity|up regulation of glucosylceramidase activity|up-regulation of beta-glucosylceramidase activity|activation of beta-glucosylceramidase activity|positive regulation of beta-D-glucocerebrosidase activity|activation of D-glucosyl-N-acylsphingosine glucohydrolase activity|up-regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity|activation of glucosylceramidase activity|up-regulation of glucosylcerebrosidase activity|activation of glucosylcerebrosidase activity|up regulation of beta-D-glucocerebrosidase activity|upregulation of glucocerebrosidase activity|up regulation of glucosylsphingosine beta-glucosidase activity|upregulation of beta-glucocerebrosidase activity|activation of glucosylsphingosine beta-glucosidase activity|up-regulation of acid beta-glucosidase activity|activation of acid beta-glucosidase activity|positive regulation of glucosylsphingosine beta-glucosidase activity|upregulation of glucosphingosine glucosylhydrolase activity|up-regulation of glucosylsphingosine beta-D-glucosidase activity|positive regulation of GlcCer-beta-glucosidase activity|upregulation of psychosine hydrolase activity|up regulation of ceramide glucosidase activity|up regulation of GlcCer-beta-glucosidase activity|activation of ceramide glucosidase activity|positive regulation of beta-glucosylceramidase activity|positive regulation of ceramide glucosidase activity|positive regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity|up regulation of beta-glucosylceramidase activity|upregulation of beta-D-glucocerebrosidase activity|activation of beta-glucocerebrosidase activity|positive regulation of glucosylcerebrosidase activity|up-regulation of glucosylceramidase activity|up regulation of glucocerebrosidase activity|up-regulation of beta-glucocerebrosidase activity|activation of glucocerebrosidase activity|up regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity|up regulation of glucosylcerebrosidase activity|positive regulation of acid beta-glucosidase activity|positive regulation of glucocerebrosidase activity|up-regulation of glucosylsphingosine beta-glucosidase activity|upregulation of glucosylsphingosine beta-D-glucosidase activity|up regulation of glucosphingosine glucosylhydrolase activity|activation of glucosphingosine glucosylhydrolase activity|up regulation of acid beta-glucosidase activity|up regulation of psychosine hydrolase activity|positive regulation of glucosphingosine glucosylhydrolase activity|upregulation of GlcCer-beta-glucosidase activity|activation of psychosine hydrolase activity|positive regulation of psychosine hydrolase activity|up-regulation of ceramide glucosidase activity|activation of beta-D-glucocerebrosidase activity|up-regulation of beta-D-glucocerebrosidase activity|upregulation of glucosylceramidase activity|upregulation of beta-glucosylceramidase activity Any process that activates or increases the frequency, rate or extent of glucosylceramidase activity. GO:0090327 negative regulation of locomotion involved in locomotory behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090327 Any process that decreases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement. GO:1905126 regulation of axo-dendritic protein transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905126 regulation of axonal protein transport Any process that modulates the frequency, rate or extent of axo-dendritic protein transport. GO:0090328 regulation of olfactory learning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090328 Any process that modulates the rate, frequency, or extent of olfactory learning. Olfactory learning is any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue. GO:1905127 negative regulation of axo-dendritic protein transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905127 down-regulation of axo-dendritic protein transport|inhibition of axo-dendritic protein transport|down-regulation of axonal protein transport|negative regulation of axonal protein transport|downregulation of axonal protein transport|down regulation of axo-dendritic protein transport|down regulation of axonal protein transport|downregulation of axo-dendritic protein transport|inhibition of axonal protein transport Any process that stops, prevents or reduces the frequency, rate or extent of axo-dendritic protein transport. GO:0090325 regulation of locomotion involved in locomotory behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090325 Any process that modulates the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement. GO:1905128 positive regulation of axo-dendritic protein transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905128 up-regulation of axonal protein transport|up-regulation of axo-dendritic protein transport|activation of axonal protein transport|positive regulation of axonal protein transport|up regulation of axonal protein transport|upregulation of axo-dendritic protein transport|upregulation of axonal protein transport|up regulation of axo-dendritic protein transport|activation of axo-dendritic protein transport Any process that activates or increases the frequency, rate or extent of axo-dendritic protein transport. GO:0090326 positive regulation of locomotion involved in locomotory behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090326 Any process that increases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement. GO:1905129 endocannabinoid signaling pathway involved in trans-synaptic signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905129 endocannabinoid signalling pathway involved in trans-synaptic signaling by endocannabinoid Any endocannabinoid signaling pathway that is involved in trans-synaptic signaling by endocannabinoid. GO:0090329 regulation of DNA-dependent DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090329 Any process that modulates the rate, frequency, or extent of DNA-dependent DNA replication, the process in which new strands of DNA are synthesized, using parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands. GO:0090320 regulation of chylomicron remnant clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090320 Any process that modulates the rate, frequency or extent of chylomicron remnant clearance. Chylomicron clearance is the process in which a chylomicron remnant is removed from the blood via receptor-mediated endocytosis into liver cells and its constituent parts degraded. GO:0090323 prostaglandin secretion involved in immune response biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0090323 The regulated release of a prostaglandin that contributes to the immune response. Prostaglandins are a group of biologically active metabolites which contain a cyclopentane ring. GO:0090324 negative regulation of oxidative phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090324 Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis. GO:0090321 positive regulation of chylomicron remnant clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090321 Any process that increases the rate, frequency or extent of chylomicron remnant clearance. Chylomicron clearance is the process in which a chylomicron remnant is removed from the blood via receptor-mediated endocytosis into liver cells and its constituent parts degraded. GO:0090322 regulation of superoxide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090322 regulation of superoxide metabolism Any process that modulates the rate, frequency, or extent of superoxide metabolism, the chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species. GO:1905140 regulation of apical ectodermal ridge formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905140 regulation of AER formation|regulation of apical epidermal ridge formation|regulation of crista ectodermalis apicalis formation Any process that modulates the frequency, rate or extent of apical ectodermal ridge formation. GO:1905141 negative regulation of apical ectodermal ridge formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905141 downregulation of apical ectodermal ridge formation|down-regulation of apical epidermal ridge formation|negative regulation of apical epidermal ridge formation|inhibition of crista ectodermalis apicalis formation|inhibition of AER formation|downregulation of apical epidermal ridge formation|down-regulation of apical ectodermal ridge formation|down regulation of AER formation|down regulation of apical epidermal ridge formation|downregulation of AER formation|negative regulation of crista ectodermalis apicalis formation|down-regulation of crista ectodermalis apicalis formation|inhibition of apical epidermal ridge formation|inhibition of apical ectodermal ridge formation|down-regulation of AER formation|negative regulation of AER formation|downregulation of crista ectodermalis apicalis formation|down regulation of apical ectodermal ridge formation|down regulation of crista ectodermalis apicalis formation Any process that stops, prevents or reduces the frequency, rate or extent of apical ectodermal ridge formation. GO:1905142 positive regulation of apical ectodermal ridge formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905142 up regulation of apical ectodermal ridge formation|positive regulation of apical epidermal ridge formation|upregulation of AER formation|up regulation of apical epidermal ridge formation|up-regulation of crista ectodermalis apicalis formation|upregulation of apical epidermal ridge formation|up regulation of AER formation|up-regulation of apical ectodermal ridge formation|positive regulation of AER formation|positive regulation of crista ectodermalis apicalis formation|up regulation of crista ectodermalis apicalis formation|activation of AER formation|upregulation of apical ectodermal ridge formation|up-regulation of apical epidermal ridge formation|up-regulation of AER formation|upregulation of crista ectodermalis apicalis formation Any process that activates or increases the frequency, rate or extent of apical ectodermal ridge formation. GO:1905143 eukaryotic translation initiation factor 2 complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905143 eukaryotic translation initiation factor 2 complex formation|eIF2 formation|eIF-2 assembly|eIF-2 formation|eIF2 assembly The aggregation, arrangement and bonding together of a set of components to form an eukaryotic translation initiation factor 2 complex. GO:1905144 response to acetylcholine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905144 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus. GO:1905145 cellular response to acetylcholine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905145 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus. GO:1905146 lysosomal protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905146 cellular protein catabolic process in lysosome|lysosomal proteolysis|cellular protein degradation in lysosome|proteolysis within lysosome|cellular protein breakdown in lysosome|lysosomal protein degradation|cellular protein catabolism in lysosome|lysosomal protein catabolism Any cellular protein catabolic process that takes place in a lysosome. GO:0090338 positive regulation of formin-nucleated actin cable assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090338 Any process that increases the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins. GO:1905136 dethiobiotin import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905136 dethiobiotin import|dethiobiotin import into cell The directed movement of dethiobiotin from outside of a cell, across the plasma membrane and into the cytosol. CHEBI:5337 (1E,4E)-germacrene B biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_5337 GO:1905137 regulation of viral DNA genome packaging via site-specific sequence recognition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905137 Any process that modulates the frequency, rate or extent of viral DNA genome packaging via site-specific sequence recognition. GO:0090339 negative regulation of formin-nucleated actin cable assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090339 Any process that decreases the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins. GO:1905138 positive regulation of viral DNA genome packaging via site-specific sequence recognition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905138 up regulation of viral DNA genome packaging via site-specific sequence recognition|activation of viral DNA genome packaging via site-specific sequence recognition|up-regulation of viral DNA genome packaging via site-specific sequence recognition|upregulation of viral DNA genome packaging via site-specific sequence recognition Any process that activates or increases the frequency, rate or extent of viral DNA genome packaging via site-specific sequence recognition. GO:0090336 positive regulation of brown fat cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090336 Any process that increases the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria. GO:1905139 apical ectodermal ridge formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905139 crista ectodermalis apicalis formation|AER formation|apical epidermal ridge formation The process that gives rise to the apical ectodermal ridge. This process pertains to the initial formation of a structure from unspecified parts. GO:0090337 regulation of formin-nucleated actin cable assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090337 Any process that modulates the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins. GO:0090330 regulation of platelet aggregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090330 Any process that modulates the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules. GO:0090331 negative regulation of platelet aggregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090331 platelet disaggregation Any process that decreases the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules. GO:0090334 regulation of cell wall (1->3)-beta-D-glucan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090334 regulation of cell wall 1,3-beta-D-glucan biosynthetic process|regulation of cell wall 1,3-beta-glucan biosynthetic process Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells. GO:0090335 regulation of brown fat cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090335 Any process that modulates the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria. GO:0090332 stomatal closure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090332 The process of closing of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange. GO:0090333 regulation of stomatal closure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090333 Any process that modulates the rate, frequency, or extent of stomatal closure. Stomatal closure is the process of closing of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange. GO:1905150 regulation of voltage-gated sodium channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905150 regulation of voltage gated sodium channel activity|regulation of voltage-dependent sodium channel activity|regulation of voltage-sensitive sodium channel|regulation of voltage-gated sodium ion channel activity Any process that modulates the frequency, rate or extent of voltage-gated sodium channel activity. GO:1905151 negative regulation of voltage-gated sodium channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905151 downregulation of voltage-gated sodium ion channel activity|down-regulation of voltage-gated sodium channel activity|inhibition of voltage-dependent sodium channel activity|down regulation of voltage gated sodium channel activity|inhibition of voltage-gated sodium channel activity|negative regulation of voltage-gated sodium ion channel activity|down-regulation of voltage-gated sodium ion channel activity|downregulation of voltage gated sodium channel activity|negative regulation of voltage-sensitive sodium channel|down-regulation of voltage-sensitive sodium channel|down regulation of voltage-dependent sodium channel activity|inhibition of voltage-gated sodium ion channel activity|downregulation of voltage-dependent sodium channel activity|down regulation of voltage-gated sodium channel activity|negative regulation of voltage gated sodium channel activity|down-regulation of voltage gated sodium channel activity|downregulation of voltage-sensitive sodium channel|downregulation of voltage-gated sodium channel activity|down regulation of voltage-sensitive sodium channel|down-regulation of voltage-dependent sodium channel activity|negative regulation of voltage-dependent sodium channel activity|inhibition of voltage gated sodium channel activity|down regulation of voltage-gated sodium ion channel activity|inhibition of voltage-sensitive sodium channel Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated sodium channel activity. GO:1905152 positive regulation of voltage-gated sodium channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905152 up-regulation of voltage-dependent sodium channel activity|up regulation of voltage-gated sodium ion channel activity|upregulation of voltage gated sodium channel activity|activation of voltage-gated sodium ion channel activity|positive regulation of voltage-gated sodium ion channel activity|activation of voltage-sensitive sodium channel|up-regulation of voltage-sensitive sodium channel|up-regulation of voltage-gated sodium channel activity|upregulation of voltage-dependent sodium channel activity|up regulation of voltage gated sodium channel activity|activation of voltage gated sodium channel activity|positive regulation of voltage gated sodium channel activity|up-regulation of voltage-gated sodium ion channel activity|upregulation of voltage-gated sodium channel activity|positive regulation of voltage-sensitive sodium channel|up regulation of voltage-sensitive sodium channel|up regulation of voltage-dependent sodium channel activity|activation of voltage-dependent sodium channel activity|positive regulation of voltage-dependent sodium channel activity|upregulation of voltage-gated sodium ion channel activity|up-regulation of voltage gated sodium channel activity|up regulation of voltage-gated sodium channel activity|activation of voltage-gated sodium channel activity|upregulation of voltage-sensitive sodium channel Any process that activates or increases the frequency, rate or extent of voltage-gated sodium channel activity. GO:1905153 regulation of membrane invagination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905153 Any process that modulates the frequency, rate or extent of membrane invagination. GO:1905154 negative regulation of membrane invagination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905154 inhibition of membrane invagination|down regulation of membrane invagination|downregulation of membrane invagination|down-regulation of membrane invagination Any process that stops, prevents or reduces the frequency, rate or extent of membrane invagination. GO:1905155 positive regulation of membrane invagination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905155 up-regulation of membrane invagination|upregulation of membrane invagination|up regulation of membrane invagination|activation of membrane invagination Any process that activates or increases the frequency, rate or extent of membrane invagination. GO:1905156 negative regulation of photosynthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905156 down-regulation of photosynthesis|downregulation of photosynthesis|down regulation of photosynthesis|inhibition of photosynthesis Any process that stops, prevents or reduces the frequency, rate or extent of photosynthesis. GO:1905157 positive regulation of photosynthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905157 up regulation of photosynthesis|upregulation of photosynthesis|activation of photosynthesis|up-regulation of photosynthesis Any process that activates or increases the frequency, rate or extent of photosynthesis. GO:0090305 nucleic acid phosphodiester bond hydrolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090305 nucleic acid cleavage The nucleic acid metabolic process in which the phosphodiester bonds between nucleotides are cleaved by hydrolysis. GO:1905147 regulation of smooth muscle hypertrophy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905147 Any process that modulates the frequency, rate or extent of smooth muscle hypertrophy. GO:1905148 negative regulation of smooth muscle hypertrophy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905148 down regulation of smooth muscle hypertrophy|downregulation of smooth muscle hypertrophy|down-regulation of smooth muscle hypertrophy|inhibition of smooth muscle hypertrophy Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle hypertrophy. GO:0090306 spindle assembly involved in meiosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090306 meiotic spindle assembly The aggregation, arrangement and bonding together of a set of components to form the spindle that contributes to the process of meiosis. GO:0090303 positive regulation of wound healing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090303 Any process that increases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury. GO:1905149 positive regulation of smooth muscle hypertrophy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905149 upregulation of smooth muscle hypertrophy|up regulation of smooth muscle hypertrophy|activation of smooth muscle hypertrophy|up-regulation of smooth muscle hypertrophy Any process that activates or increases the frequency, rate or extent of smooth muscle hypertrophy. GO:0090304 nucleic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090304 Any cellular metabolic process involving nucleic acids. GO:0090309 positive regulation of DNA methylation-dependent heterochromatin assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090309 positive regulation of methylation-dependent chromatin silencing Any process that increases the rate, frequency, or extent of the repression of transcription by methylation of DNA, leading to the formation of heterochromatin. GO:0090307 mitotic spindle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090307 spindle assembly involved in mitosis Mitotic bipolar spindle assembly begins with spindle microtubule nucleation from the separated spindle pole body, includes spindle elongation during prometaphase, and is complete when all kinetochores are stably attached the spindle, and the spindle assembly checkpoint is satisfied. GO:0090308 regulation of DNA methylation-dependent heterochromatin assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090308 regulation of methylation-dependent chromatin silencing Any process that modulates the rate, frequency, or extent of the repression of transcription by methylation of DNA, leading to the formation of heterochromatin. GO:0090301 negative regulation of neural crest formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090301 Any process that decreases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes. GO:0090302 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090302 GO:0090300 positive regulation of neural crest formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090300 Any process that increases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes. GO:1905160 obsolete positive regulation of Factor XII activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905160 up-regulation of Factor XII activation|up-regulation of Hageman factor activation|upregulation of Factor XII activation|upregulation of Hageman factor activation|up regulation of Factor XII activation|activation of Factor XII activation|up regulation of Hageman factor activation|activation of Hageman factor activation|positive regulation of Hageman factor activation OBSOLETE. Any process that activates or increases the frequency, rate or extent of Factor XII activation. GO:1905161 protein localization to phagocytic vesicle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905161 protein localization in phagocytic vesicle|protein localisation to phagosome|protein recruitment to phagosome|protein localisation to phagocytic vesicle|protein localisation in phagocytic vesicle A process in which a protein is transported to, or maintained in, a location within a phagocytic vesicle. GO:1905162 regulation of phagosome maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905162 Any process that modulates the frequency, rate or extent of phagosome maturation. GO:1905163 negative regulation of phagosome maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905163 downregulation of phagosome maturation|down regulation of phagosome maturation|inhibition of phagosome maturation|down-regulation of phagosome maturation Any process that stops, prevents or reduces the frequency, rate or extent of phagosome maturation. GO:1905164 positive regulation of phagosome maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905164 up regulation of phagosome maturation|upregulation of phagosome maturation|activation of phagosome maturation|up-regulation of phagosome maturation Any process that activates or increases the frequency, rate or extent of phagosome maturation. GO:1905165 regulation of lysosomal protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905165 regulation of lysosomal protein catabolism|regulation of lysosomal protein degradation|regulation of cellular protein catabolism in lysosome|regulation of cellular protein degradation in lysosome|regulation of lysosomal proteolysis|regulation of proteolysis within lysosome|regulation of cellular protein breakdown in lysosome|regulation of cellular protein catabolic process in lysosome Any process that modulates the frequency, rate or extent of lysosomal protein catabolic process. GO:1905166 negative regulation of lysosomal protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905166 inhibition of cellular protein catabolic process in lysosome|down-regulation of lysosomal proteolysis|negative regulation of lysosomal proteolysis|down-regulation of proteolysis within lysosome|inhibition of lysosomal protein catabolic process|negative regulation of proteolysis within lysosome|downregulation of lysosomal protein catabolism|down regulation of lysosomal protein degradation|down regulation of lysosomal protein catabolism|inhibition of lysosomal protein catabolism|negative regulation of cellular protein degradation in lysosome|down-regulation of cellular protein degradation in lysosome|down regulation of cellular protein catabolism in lysosome|downregulation of lysosomal protein degradation|downregulation of cellular protein catabolism in lysosome|inhibition of lysosomal proteolysis|down-regulation of cellular protein breakdown in lysosome|negative regulation of cellular protein breakdown in lysosome|inhibition of proteolysis within lysosome|down regulation of lysosomal protein catabolic process|downregulation of cellular protein degradation in lysosome|negative regulation of cellular protein catabolic process in lysosome|down-regulation of cellular protein catabolic process in lysosome|negative regulation of lysosomal protein degradation|down-regulation of lysosomal protein degradation|downregulation of lysosomal protein catabolic process|down regulation of lysosomal proteolysis|down-regulation of cellular protein catabolism in lysosome|down regulation of cellular protein degradation in lysosome|down regulation of proteolysis within lysosome|negative regulation of cellular protein catabolism in lysosome|inhibition of cellular protein degradation in lysosome|downregulation of cellular protein breakdown in lysosome|downregulation of lysosomal proteolysis|downregulation of proteolysis within lysosome|inhibition of lysosomal protein degradation|down-regulation of lysosomal protein catabolism|down regulation of cellular protein breakdown in lysosome|downregulation of cellular protein catabolic process in lysosome|negative regulation of lysosomal protein catabolism|inhibition of cellular protein catabolism in lysosome|inhibition of cellular protein breakdown in lysosome|down-regulation of lysosomal protein catabolic process|down regulation of cellular protein catabolic process in lysosome Any process that stops, prevents or reduces the frequency, rate or extent of lysosomal protein catabolic process. GO:1905167 positive regulation of lysosomal protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905167 positive regulation of proteolysis within lysosome|up regulation of lysosomal protein catabolism|up-regulation of cellular protein degradation in lysosome|upregulation of cellular protein catabolic process in lysosome|activation of cellular protein degradation in lysosome|upregulation of lysosomal protein degradation|up-regulation of lysosomal protein catabolic process|activation of lysosomal proteolysis|activation of proteolysis within lysosome|upregulation of cellular protein catabolism in lysosome|up-regulation of cellular protein breakdown in lysosome|activation of cellular protein breakdown in lysosome|up-regulation of lysosomal proteolysis|upregulation of lysosomal protein catabolism|up-regulation of cellular protein catabolic process in lysosome|up-regulation of proteolysis within lysosome|activation of cellular protein catabolic process in lysosome|upregulation of lysosomal protein catabolic process|positive regulation of cellular protein degradation in lysosome|up regulation of lysosomal protein degradation|up regulation of cellular protein degradation in lysosome|positive regulation of lysosomal protein degradation|activation of lysosomal protein degradation|up regulation of cellular protein catabolism in lysosome|positive regulation of cellular protein catabolism in lysosome|positive regulation of cellular protein breakdown in lysosome|activation of cellular protein catabolism in lysosome|upregulation of lysosomal proteolysis|up regulation of cellular protein breakdown in lysosome|upregulation of proteolysis within lysosome|up-regulation of lysosomal protein catabolism|activation of lysosomal protein catabolism|positive regulation of cellular protein catabolic process in lysosome|up regulation of lysosomal protein catabolic process|up regulation of cellular protein catabolic process in lysosome|activation of lysosomal protein catabolic process|upregulation of cellular protein degradation in lysosome|up-regulation of lysosomal protein degradation|up regulation of lysosomal proteolysis|up-regulation of cellular protein catabolism in lysosome|up regulation of proteolysis within lysosome|upregulation of cellular protein breakdown in lysosome|positive regulation of lysosomal proteolysis|positive regulation of lysosomal protein catabolism Any process that activates or increases the frequency, rate or extent of lysosomal protein catabolic process. GO:1905168 positive regulation of double-strand break repair via homologous recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905168 up-regulation of HDR|upregulation of Rad51-dependent recombinational repair|up regulation of HRR|positive regulation of homology-directed repair|up-regulation of homologous recombinational repair|up-regulation of double-strand break repair via homologous recombination|activation of HRR|up regulation of homology-directed repair|positive regulation of HRR|upregulation of Rhp51-dependent recombinational repair|up-regulation of Rad51-dependent recombinational repair|upregulation of HDR|activation of Rad51-dependent recombinational repair|upregulation of homologous recombinational repair|upregulation of double-strand break repair via homologous recombination|upregulation of homology-directed repair|up-regulation of HRR|up-regulation of Rhp51-dependent recombinational repair|activation of Rhp51-dependent recombinational repair|up regulation of HDR|positive regulation of Rad51-dependent recombinational repair|positive regulation of HDR|activation of HDR|up regulation of homologous recombinational repair|up regulation of double-strand break repair via homologous recombination|up-regulation of homology-directed repair|up regulation of Rad51-dependent recombinational repair|positive regulation of homologous recombinational repair|activation of homologous recombinational repair|activation of double-strand break repair via homologous recombination|upregulation of HRR|activation of homology-directed repair|positive regulation of Rhp51-dependent recombinational repair|up regulation of Rhp51-dependent recombinational repair Any process that activates or increases the frequency, rate or extent of double-strand break repair via homologous recombination. GO:1905158 obsolete regulation of Factor XII activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905158 regulation of Hageman factor activation OBSOLETE. Any process that modulates the frequency, rate or extent of Factor XII activation. GO:0090316 positive regulation of intracellular protein transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090316 Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells. GO:1905159 obsolete negative regulation of Factor XII activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905159 down regulation of Factor XII activation|downregulation of Factor XII activation|down regulation of Hageman factor activation|downregulation of Hageman factor activation|down-regulation of Factor XII activation|down-regulation of Hageman factor activation|negative regulation of Hageman factor activation|inhibition of Factor XII activation|inhibition of Hageman factor activation OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of Factor XII activation. GO:0090317 negative regulation of intracellular protein transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090317 Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells. GO:0090314 positive regulation of protein targeting to membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090314 Any process that increases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein. GO:0090315 negative regulation of protein targeting to membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090315 Any process that decreases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein. GO:0090318 regulation of chylomicron remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090318 Any process that modulates the rate, frequency, or extent of chylomicron remodeling. Chylomicron remodeling is the acquisition, loss or modification of a protein or lipid within a chylomicron, including the hydrolysis of triglyceride by lipoprotein lipase and the subsequent loss of free fatty acid. GO:0090319 positive regulation of chylomicron remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090319 Any process that increases the rate, frequency, or extent of chylomicron remodeling. Chylomicron remodeling is the acquisition, loss or modification of a protein or lipid within a chylomicron, including the hydrolysis of triglyceride by lipoprotein lipase and the subsequent loss of free fatty acid. GO:0090312 positive regulation of protein deacetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090312 positive regulation of protein amino acid deacetylation Any process that increases the rate, frequency, or extent of protein deacetylation, the removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid. GO:0090313 regulation of protein targeting to membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090313 Any process that modulates the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein. GO:0090310 negative regulation of DNA methylation-dependent heterochromatin assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090310 negative regulation of methylation-dependent chromatin silencing Any process that decreases the rate, frequency, or extent of the repression of transcription by methylation of DNA, leading to the formation of heterochromatin. GO:0090311 regulation of protein deacetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090311 regulation of protein amino acid deacetylation Any process that modulates the rate, frequency, or extent of protein deacetylation, the removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid. GO:0090360 platelet-derived growth factor production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0090360 The appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:1905170 negative regulation of protein localization to phagocytic vesicle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905170 down-regulation of protein localization to phagocytic vesicle|downregulation of protein recruitment to phagosome|downregulation of protein localisation to phagocytic vesicle|down-regulation of protein localisation in phagocytic vesicle|negative regulation of protein localisation in phagocytic vesicle|down regulation of protein recruitment to phagosome|down regulation of protein localisation to phagosome|down regulation of protein localisation to phagocytic vesicle|inhibition of protein recruitment to phagosome|inhibition of protein localisation to phagocytic vesicle|downregulation of protein localisation to phagosome|downregulation of protein localization to phagocytic vesicle|down-regulation of protein localization in phagocytic vesicle|negative regulation of protein localization in phagocytic vesicle|downregulation of protein localisation in phagocytic vesicle|down regulation of protein localization to phagocytic vesicle|inhibition of protein localization to phagocytic vesicle|down regulation of protein localisation in phagocytic vesicle|inhibition of protein localisation in phagocytic vesicle|down-regulation of protein localisation to phagosome|negative regulation of protein localisation to phagosome|downregulation of protein localization in phagocytic vesicle|down regulation of protein localization in phagocytic vesicle|down-regulation of protein recruitment to phagosome|negative regulation of protein recruitment to phagosome|inhibition of protein localization in phagocytic vesicle|inhibition of protein localisation to phagosome|down-regulation of protein localisation to phagocytic vesicle|negative regulation of protein localisation to phagocytic vesicle Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to phagocytic vesicle. GO:1905171 positive regulation of protein localization to phagocytic vesicle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905171 upregulation of protein localization in phagocytic vesicle|activation of protein localization to phagocytic vesicle|positive regulation of protein recruitment to phagosome|up-regulation of protein localisation in phagocytic vesicle|activation of protein localisation in phagocytic vesicle|positive regulation of protein localisation to phagocytic vesicle|up regulation of protein recruitment to phagosome|up regulation of protein localisation to phagocytic vesicle|upregulation of protein localisation to phagosome|up-regulation of protein localization in phagocytic vesicle|activation of protein localization in phagocytic vesicle|up regulation of protein localization to phagocytic vesicle|positive regulation of protein localisation in phagocytic vesicle|upregulation of protein recruitment to phagosome|up regulation of protein localisation in phagocytic vesicle|upregulation of protein localisation to phagocytic vesicle|up regulation of protein localisation to phagosome|positive regulation of protein localization in phagocytic vesicle|activation of protein localisation to phagosome|positive regulation of protein localisation to phagosome|upregulation of protein localization to phagocytic vesicle|up regulation of protein localization in phagocytic vesicle|up-regulation of protein recruitment to phagosome|up-regulation of protein localisation to phagocytic vesicle|activation of protein recruitment to phagosome|activation of protein localisation to phagocytic vesicle|upregulation of protein localisation in phagocytic vesicle|up-regulation of protein localisation to phagosome|up-regulation of protein localization to phagocytic vesicle Any process that activates or increases the frequency, rate or extent of protein localization to phagocytic vesicle. GO:1905172 RISC complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1905172 RNA-induced silencing complex binding Interacting selectively and non-covalently with a RISC complex. GO:1905173 eukaryotic translation initiation factor 2B complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905173 eif2B assembly|eIF-2B formation|eIF-2B assembly|eif2B formation|eukaryotic translation initiation factor 2B complex formation The aggregation, arrangement and bonding together of a set of components to form an eukaryotic translation initiation factor 2B complex. GO:1905174 regulation of vascular associated smooth muscle cell dedifferentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905174 regulation of vascular smooth muscle cell dedifferentiation Any process that modulates the frequency, rate or extent of vascular smooth muscle cell dedifferentiation. GO:1905175 negative regulation of vascular associated smooth muscle cell dedifferentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905175 inhibition of vascular smooth muscle cell dedifferentiation|negative regulation of vascular smooth muscle cell dedifferentiation|down regulation of vascular smooth muscle cell dedifferentiation|downregulation of vascular smooth muscle cell dedifferentiation|down-regulation of vascular smooth muscle cell dedifferentiation Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell dedifferentiation. GO:1905176 positive regulation of vascular associated smooth muscle cell dedifferentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905176 up-regulation of vascular smooth muscle cell dedifferentiation|positive regulation of vascular smooth muscle cell dedifferentiation|upregulation of vascular smooth muscle cell dedifferentiation|up regulation of vascular smooth muscle cell dedifferentiation|activation of vascular smooth muscle cell dedifferentiation Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell dedifferentiation. GO:1905177 tracheary element differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905177 The process in which a relatively unspecialized cell acquires the specialized features of a tracheary element. GO:1905178 regulation of cardiac muscle tissue regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905178 Any process that modulates the frequency, rate or extent of cardiac muscle tissue regeneration. GO:1905179 negative regulation of cardiac muscle tissue regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905179 down-regulation of cardiac muscle tissue regeneration|downregulation of cardiac muscle tissue regeneration|down regulation of cardiac muscle tissue regeneration|inhibition of cardiac muscle tissue regeneration Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle tissue regeneration. GO:1905169 regulation of protein localization to phagocytic vesicle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905169 regulation of protein localisation to phagocytic vesicle|regulation of protein localisation to phagosome|regulation of protein localisation in phagocytic vesicle|regulation of protein localization in phagocytic vesicle|regulation of protein recruitment to phagosome Any process that modulates the frequency, rate or extent of protein localization to phagocytic vesicle. GO:0090369 ornithine carbamoyltransferase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090369 Stops, prevents, or reduces ornithine carbamoyltransferase activity, the catalysis of the reaction: carbamoyl phosphate + L-ornithine = phosphate + L-citrulline. GO:0090363 regulation of proteasome core complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090363 Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of a mature, active 20S proteasome core particle complex that does not contain any regulatory particles. GO:0090364 regulation of proteasome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090364 Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of a mature, active proteasome complex. GO:0090361 regulation of platelet-derived growth factor production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090361 Any process that modulates the rate, frequency, or extent of the appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0090362 positive regulation of platelet-derived growth factor production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090362 Any process that increases the rate, frequency, or extent of the appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0090367 negative regulation of mRNA modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090367 Any process that decreases the rate, frequency, or extent of the covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically. GO:0090368 regulation of ornithine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090368 Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways involving ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis. GO:0090365 regulation of mRNA modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090365 regulation of mRNA editing Any process that modulates the rate, frequency, or extent of the covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically. GO:0090366 positive regulation of mRNA modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090366 Any process that increases the rate, frequency, or extent of the covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically. GO:0090370 negative regulation of cholesterol efflux biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090370 Any process that decreases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle. GO:1905180 positive regulation of cardiac muscle tissue regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905180 upregulation of cardiac muscle tissue regeneration|up-regulation of cardiac muscle tissue regeneration|activation of cardiac muscle tissue regeneration|up regulation of cardiac muscle tissue regeneration Any process that activates or increases the frequency, rate or extent of cardiac muscle tissue regeneration. GO:0090371 regulation of glycerol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090371 Any process that modulates the rate, frequency, or extent of the directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:1905181 regulation of urease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905181 regulation of urea amidohydrolase activity Any process that modulates the frequency, rate or extent of urease activity. GO:1905182 positive regulation of urease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905182 up regulation of urease activity|activation of urease activity|upregulation of urea amidohydrolase activity|up-regulation of urease activity|activation of urea amidohydrolase activity|up-regulation of urea amidohydrolase activity|upregulation of urease activity|positive regulation of urea amidohydrolase activity|up regulation of urea amidohydrolase activity Any process that activates or increases the frequency, rate or extent of urease activity. GO:1905183 negative regulation of protein serine/threonine phosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905183 down regulation of serine/threonine specific protein phosphatase activity|down regulation of protein serine/threonine phosphatase activity|inhibition of serine/threonine specific protein phosphatase activity|downregulation of protein serine/threonine phosphatase activity|down-regulation of protein serine/threonine phosphatase activity|down-regulation of serine/threonine specific protein phosphatase activity|negative regulation of serine/threonine specific protein phosphatase activity|inhibition of protein serine/threonine phosphatase activity|downregulation of serine/threonine specific protein phosphatase activity Any process that stops, prevents or reduces the frequency, rate or extent of protein serine/threonine phosphatase activity. GO:1905184 positive regulation of protein serine/threonine phosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905184 upregulation of protein serine/threonine phosphatase activity|upregulation of serine/threonine specific protein phosphatase activity|up regulation of protein serine/threonine phosphatase activity|activation of protein serine/threonine phosphatase activity|activation of serine/threonine specific protein phosphatase activity|up-regulation of serine/threonine specific protein phosphatase activity|up-regulation of protein serine/threonine phosphatase activity|positive regulation of serine/threonine specific protein phosphatase activity|up regulation of serine/threonine specific protein phosphatase activity Any process that activates or increases the frequency, rate or extent of protein serine/threonine phosphatase activity. GO:1905185 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1905185 GO:1905186 regulation of metaphase/anaphase transition of meiosis I biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905186 regulation of meiosis I metaphase/anaphase transition|regulation of first meiotic metaphase/anaphase transition Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiosis I. GO:1905187 negative regulation of metaphase/anaphase transition of meiosis I biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905187 Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiosis I. GO:1905188 positive regulation of metaphase/anaphase transition of meiosis I biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905188 positive regulation of meiosis I metaphase/anaphase transition Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiosis I. GO:1905189 regulation of metaphase/anaphase transition of meiosis II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905189 regulation of meiosis II metaphase/anaphase transition Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiosis II. GO:0090374 oligopeptide export from mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090374 The process in which an oligopeptide is transported out of the mitochondrial matrix. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages. CHEBI:5373 (S)-glaucine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_5373 GO:0090375 negative regulation of transcription from RNA polymerase II promoter in response to iron ion starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090375 negative regulation of transcription from RNA polymerase II promoter in response to iron deficiency Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of iron ions. GO:0090372 positive regulation of glycerol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090372 Any process that increases the rate, frequency, or extent of the directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0090373 negative regulation of glycerol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090373 Any process that decreases the rate, frequency, or extent of the directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0090378 seed trichome elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090378 The process in which a seed trichome irreversibly increases in size in one [spatial] dimension or along one axis, resulting in the morphogenesis of the cell. GO:0090379 secondary cell wall biogenesis involved in seed trichome differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090379 secondary cell wall biosynthesis involved in seed trichome differentiation|seed trichome secondary wall biosynthesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of inextensible cellulose- and pectin-containing cell walls that are formed between the plasma membrane and primary cell wall of seed trichomes after cell expansion is complete. GO:0090376 seed trichome differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090376 seed hair differentiation|seed trichome development|cotton fiber development The process in which a relatively unspecialized epidermal cell acquires the specialized features of a seed trichome. A seed trichome is a trichome that develops from seed coat epidermis and is often long with putative dispersal function. GO:0090377 seed trichome initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090377 seed trichome fate commitment The process in which the developmental fate of an epidermal cell becomes restricted such that it will develop into a seed trichome, causing a change in the orientation of cell division in the ovule epidermis at or just before anthesis. GO:1905190 negative regulation of metaphase/anaphase transition of meiosis II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905190 negative regulation of meiosis II metaphase/anaphase transition Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiosis II. GO:1905191 positive regulation of metaphase/anaphase transition of meiosis II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905191 positive regulation of meiosis II metaphase/anaphase transition Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiosis II. GO:1905192 regulation of chloroplast fission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905192 regulation of chloroplast division Any process that modulates the frequency, rate or extent of chloroplast fission. GO:1905193 negative regulation of chloroplast fission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905193 down regulation of chloroplast fission|downregulation of chloroplast fission|down-regulation of chloroplast division|negative regulation of chloroplast division|down-regulation of chloroplast fission|downregulation of chloroplast division|inhibition of chloroplast fission|down regulation of chloroplast division|inhibition of chloroplast division Any process that stops, prevents or reduces the frequency, rate or extent of chloroplast fission. GO:1905194 positive regulation of chloroplast fission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905194 upregulation of chloroplast division|upregulation of chloroplast fission|activation of chloroplast division|up-regulation of chloroplast division|up regulation of chloroplast fission|activation of chloroplast fission|positive regulation of chloroplast division|up regulation of chloroplast division|up-regulation of chloroplast fission Any process that activates or increases the frequency, rate or extent of chloroplast fission. GO:1905195 obsolete regulation of ATPase activity, uncoupled biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905195 regulation of adenylpyrophosphatase activity OBSOLETE. Any process that modulates the frequency, rate or extent of ATPase activity, uncoupled. GO:1905196 obsolete positive regulation of ATPase activity, uncoupled biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905196 up regulation of adenylpyrophosphatase activity|up regulation of ATPase activity, uncoupled|upregulation of adenylpyrophosphatase activity|upregulation of ATPase activity, uncoupled|up-regulation of adenylpyrophosphatase activity|activation of ATPase activity, uncoupled|up-regulation of ATPase activity, uncoupled|activation of adenylpyrophosphatase activity|positive regulation of adenylpyrophosphatase activity OBSOLETE. Any process that activates or increases the frequency, rate or extent of ATPase activity, uncoupled. GO:1905197 endocannabinoid signaling pathway involved in retrograde trans-synaptic signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905197 endocannabinoid signalling pathway involved in retrograde trans-synaptic signaling by endocannabinoid Any endocannabinoid signaling pathway that is involved in retrograde trans-synaptic signaling by endocannabinoid. GO:1905198 manchette assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905198 manchette formation The aggregation, arrangement and bonding together of a set of components to form a manchette. GO:1905199 manchette disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905199 The disaggregation of a manchette into its constituent components. GO:0090349 negative regulation of cellular organohalogen metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090349 Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving organohalogen compounds, as carried out by individual cells. GO:0090347 regulation of cellular organohalogen metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090347 Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving organohalogen compounds, as carried out by individual cells. GO:0090348 regulation of cellular organofluorine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090348 Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving organofluorine compounds, as carried out by individual cells. GO:0090341 negative regulation of secretion of lysosomal enzymes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090341 Any process that decreases the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell. GO:0016363 nuclear matrix biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016363 Wikipedia:Nuclear_matrix nucleoskeleton The dense fibrillar network lying on the inner side of the nuclear membrane. GO:0090342 regulation of cell aging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090342 Any process that modulates the rate, frequency, or extent of cell aging. Cell aging is the progression of the cell from its inception to the end of its lifespan. GO:0090340 positive regulation of secretion of lysosomal enzymes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090340 Any process that increases the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell. GO:0090345 cellular organohalogen metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090345 The chemical reactions and pathways involving organohalogen compounds, as carried out by individual cells. GO:0090346 cellular organofluorine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090346 The chemical reactions and pathways involving organofluorine compounds, as carried out by individual cells. GO:0016360 sensory organ precursor cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016360 sense organ precursor cell fate determination The process in which a cell becomes capable of differentiating autonomously into a sensory organ precursor cell regardless of its environment; upon determination, the cell fate cannot be reversed. GO:0090343 positive regulation of cell aging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090343 Any process that increases the rate, frequency, or extent of cell aging. Cell aging is the progression of the cell from its inception to the end of its lifespan. GO:0016361 activin receptor activity, type I biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016361 type I activin receptor activity Combining with activin-bound type II activin receptor to initiate a change in cell activity; upon binding, acts as a downstream transducer of activin signals. GO:0016362 activin receptor activity, type II biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016362 Reactome:R-HSA-201443 type II activin receptor activity Combining with activin to initiate a change in cell activity; upon ligand binding, binds to and catalyses the phosphorylation of a type I activin receptor. GO:0090344 negative regulation of cell aging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090344 Any process that decreases the rate, frequency, or extent of cell aging. Cell aging is the progression of the cell from its inception to the end of its lifespan. GO:0031999 negative regulation of fatty acid beta-oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031999 down regulation of fatty acid beta-oxidation|downregulation of fatty acid beta-oxidation|down-regulation of fatty acid beta-oxidation|inhibition of fatty acid beta-oxidation Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid beta-oxidation. GO:0031997 N-terminal myristoylation domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031997 Interacting selectively and non-covalently with the N-terminus of a protein that has the potential to be, or has been, modified by N-terminal myristoylation. Binding affinity is typically altered by myristoylation; for example, N-terminal myristoylation of HIV Nef increases its affinity for calmodulin. GO:0031998 regulation of fatty acid beta-oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031998 Any process that modulates the frequency, rate or extent of fatty acid bbeta-oxidation. GO:0031995 insulin-like growth factor II binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0031995 IGF-II binding Interacting selectively and non-covalently with insulin-like growth factor II. GO:0031996 thioesterase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031996 thiolesterase binding Interacting selectively and non-covalently with any thioesterase enzyme. GO:0090358 positive regulation of tryptophan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090358 positive regulation of tryptophan metabolism Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid. GO:0090359 negative regulation of abscisic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090359 negative regulation of abscisic acid biosynthesis Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of abscisic acid. GO:0090352 regulation of nitrate assimilation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090352 Any process that modulates the rate, frequency, or extent of the uptake, from the environment, of nitrates, inorganic or organic salts and esters of nitric acid and the subsequent reduction of nitrate ion to other, less highly oxidized, inorganic nitrogenous substances. GO:0031993 light transducer activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031993 Absorbing energy from one or more photons and transferring their energy to another molecule, usually a protein, within the cell. GO:0031994 insulin-like growth factor I binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0031994 IGF-I binding Interacting selectively and non-covalently with insulin-like growth factor I. GO:0090353 polygalacturonase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090353 Stops, prevents or reduces the activity of a polygalacturonase. Polygalacturonases catalyze the random hydrolysis of 1,4-alpha-D-galactosiduronic linkages in pectate and other galacturonans. GO:0031991 regulation of actomyosin contractile ring contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031991 regulation of contractile ring contraction involved in cell cycle cytokinesis|regulation of contractile ring contraction involved in cytokinesis during cell cycle Any process that modulates the frequency, rate or extent of contraction of the actomyosin ring involved in cytokinesis that takes place as part of a cell cycle. GO:0090350 negative regulation of cellular organofluorine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090350 Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving organofluorine compounds, as carried out by individual cells. GO:0090351 seedling development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090351 PO:0008037 The process whose specific outcome is the progression of the seedling over time, beginning with seed germination and ending when the first adult leaves emerge. GO:0031992 energy transducer activity biolink:MolecularActivity go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0031992 light harvesting activity|photon capture The biological transducer activity that accepts energy and converts it to another form, often by transfer to another molecule within the cell. GO:0090356 negative regulation of auxin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090356 negative regulation of auxin metabolism Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving auxins, plant hormones that regulate aspects of plant growth. GO:0031990 mRNA export from nucleus in response to heat stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031990 mRNA export from nucleus during heat stress|mRNA export from cell nucleus during heat stress The directed movement of mRNA from the nucleus to the cytoplasm during a heat stimulus, a temperature stimulus above the optimal temperature for the organism; in particular, a process that enables an organism withstand exposure to temperatures that would otherwise lethally impair poly(A)+ mRNA-nucleus export. GO:0090357 regulation of tryptophan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090357 regulation of tryptophan metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid. GO:0090354 regulation of auxin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090354 regulation of auxin metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving auxins, plant hormones that regulate aspects of plant growth. GO:0090355 positive regulation of auxin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090355 positive regulation of auxin metabolism Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving auxins, plant hormones that regulate aspects of plant growth. GO:2000508 regulation of dendritic cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000508 Any process that modulates the frequency, rate or extent of dendritic cell chemotaxis. GO:2000509 negative regulation of dendritic cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000509 Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell chemotaxis. UBERON:0018144 cervical rib biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018144 A rib that is attached to a cervical vertebra. UBERON:0018142 caudal vertebra endochondral element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018142 coccyx vertebra element|coccygeal vertebra element|tail vertebra element|caudal vertebra element Any vertebra endochondral element that is part of the caudal region of the vertebral column (tail or coccyx). UBERON:0018143 transverse process of cervical vertebra biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018143 A transverse process that is part of a cervical vertebra GO:2000500 obsolete positive regulation of induction of apoptosis in response to chemical stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000500 positive regulation of induction of apoptosis in response to chemical substance|positive regulation of induction of apoptosis in response to chemical stimulus OBSOLETE. Any process that activates or increases the frequency, rate or extent of induction of apoptosis in response to chemical stimulus. GO:2000501 regulation of natural killer cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000501 Any process that modulates the frequency, rate or extent of natural killer cell chemotaxis. GO:2000502 negative regulation of natural killer cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000502 Any process that stops, prevents or reduces the frequency, rate or extent of natural killer cell chemotaxis. GO:2000503 positive regulation of natural killer cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000503 Any process that activates or increases the frequency, rate or extent of natural killer cell chemotaxis. GO:2000504 positive regulation of blood vessel remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000504 Any process that activates or increases the frequency, rate or extent of blood vessel remodeling. GO:2000505 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2000505 GO:2000506 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2000506 GO:2000507 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2000507 CHEBI:41308 benzophenone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_41308 CHEBI:16337 phosphatidic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16337 CL:0008007 visceral muscle cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0008007 A muscle cell that is part of some visceral muscle CHEBI:16338 4-hydroxy-L-glutamate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16338 CL:0008008 striated visceral muscle cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0008008 A visceral muscle cell that is striated. Examples include the visceral muscle cells of arhtropods. CHEBI:16335 adenosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16335 CHEBI:16336 hyaluronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16336 CL:0008009 transversely striated visceral muscle cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0008009 A visceral muscle that is transversely striated. Examples include the visceral muscle cells of arthropods. CHEBI:16333 2-arylpropionic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16333 CL:0008002 skeletal muscle fiber biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0008002 A transversely striated, synctial cell of skeletal muscle. It is formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. CL:0008003 somatic muscle myotube biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0008003 A myotube that is part of some somatic muscle. Examples include arthropod somatic muscle cells. CL:0008004 somatic muscle cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0008004 A muscle cell that is part of some somatic muscle. CHEBI:16331 phloretate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16331 CHEBI:16332 D-xylulose 5-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16332 CHEBI:16330 17beta-hydroxy-5alpha-androstan-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16330 CL:0008000 non-striated muscle cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0008000 Any muscle cell in which the fibers are not organised into sarcomeres. CHEBI:90277 (2E)-tricosenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90277 CL:0008001 hematopoietic precursor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0008001 Any hematopoietic cell that is a precursor of some other hematopoietic cell type. GO:2000519 positive regulation of T-helper 1 cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000519 positive regulation of Th1 cell activation Any process that activates or increases the frequency, rate or extent of T-helper 1 cell activation. UBERON:0018135 fibrocollagenous connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018135 CHEBI:90262 alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-Cer biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90262 UBERON:0018132 tail fat pad biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018132 tail fat depot Encapsulated adipose tissue that is part of a tail. GO:2000511 regulation of granzyme A production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000511 Any process that modulates the frequency, rate or extent of granzyme A production. GO:2000512 negative regulation of granzyme A production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000512 Any process that stops, prevents or reduces the frequency, rate or extent of granzyme A production. GO:2000513 positive regulation of granzyme A production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000513 Any process that activates or increases the frequency, rate or extent of granzyme A production. GO:2000514 regulation of CD4-positive, alpha-beta T cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000514 Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell activation. GO:2000515 negative regulation of CD4-positive, alpha-beta T cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000515 Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell activation. GO:2000516 positive regulation of CD4-positive, alpha-beta T cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000516 Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell activation. GO:2000517 regulation of T-helper 1 cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000517 regulation of Th1 cell activation Any process that modulates the frequency, rate or extent of T-helper 1 cell activation. GO:2000518 negative regulation of T-helper 1 cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000518 negative regulation of Th1 cell activation Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 1 cell activation. CHEBI:16329 UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-L-lysine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16329 CL:0008017 adult skeletal muscle myoblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0008017 myogenic precursor cell A skeletal muscle myoblast that is part of a skeletal mucle. These cells are formed following acivation and division of skeletal muscle satellite cells. They form a transient population that is lost when they fuse to form skeletal muscle fibers. CHEBI:16326 alpha-D-hexose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16326 CL:0008018 somatic muscle myoblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0008018 A myoblast that is commited to developing into a somatic muscle. CHEBI:16327 2-oxosuccinamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16327 CHEBI:16324 rifamycin O biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16324 CL:0008019 mesenchymal cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0008019 mesenchyme cell A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration. GO:2000510 positive regulation of dendritic cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000510 Any process that activates or increases the frequency, rate or extent of dendritic cell chemotaxis. CHEBI:16325 lithocholic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16325 CHEBI:16322 myo-inositol 1,3,4,5,6-pentakisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16322 CHEBI:16320 (R)-3-aminoisobutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16320 CL:0008016 activated skeletal muscle satellite cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0008016 A skeletal muscle cell that has become mitotically active - typically following muscle damage. CHEBI:16321 4-carboxy-2-hydroxyhexa-2,4-dienedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16321 CHEBI:90264 L-3-sulfolactaldehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90264 CHEBI:90265 alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-ceramide(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90265 CL:0008011 skeletal muscle satellite stem cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0008011 A skeletal muscle satellite cell that divides by stem cell division. A proportion of this population undergoes symmetric stem cell division, producing two skeletal muscle satellite stem cells. The rest undergo asymmetric stem cell division - retaining their identity while budding off a daughter cell that differentiates into an adult skeletal muscle myoblast. CL:0008012 quiescent skeletal muscle satellite cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0008012 A skeletal muscle satellite cell that is mitotically quiescent. These cells are wedge shaped and have a large nuclear to cytoplasmic ratio with few organelles, a small nucleus and condensed interphase chromatin. Satellite cells typically remain in this state until activated following muscle damage. CHEBI:90266 tricosanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90266 CHEBI:90292 beta-D-Gal-(1->3)-[alpha-L-Fuc-(1->4)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90292 UBERON:0018120 right renal medulla interstitium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018120 medullary interstitial tissue of right kidney A renal medulla interstitium that is part of a right kidney. CHEBI:5391 glucagon biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_5391 GO:2000522 positive regulation of immunological synapse formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000522 positive regulation of formation of immunological synapse Any process that activates or increases the frequency, rate or extent of immunological synapse formation. GO:2000523 regulation of T cell costimulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000523 regulation of T-cell costimulation|regulation of T cell co-stimulation|regulation of T-lymphocyte costimulation|regulation of T lymphocyte costimulation|regulation of T-cell co-stimulation Any process that modulates the frequency, rate or extent of T cell costimulation. GO:2000524 negative regulation of T cell costimulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000524 negative regulation of T lymphocyte costimulation|negative regulation of T cell co-stimulation|negative regulation of T-cell costimulation|negative regulation of T-lymphocyte costimulation|negative regulation of T-cell co-stimulation Any process that stops, prevents or reduces the frequency, rate or extent of T cell costimulation. GO:2000525 positive regulation of T cell costimulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000525 positive regulation of T lymphocyte costimulation|positive regulation of T cell co-stimulation|positive regulation of T-cell co-stimulation|positive regulation of T-cell costimulation|positive regulation of T-lymphocyte costimulation Any process that activates or increases the frequency, rate or extent of T cell costimulation. GO:2000526 positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000526 positive regulation of glycoprotein biosynthetic process of formation of immunological synapse|positive regulation of glycoprotein biosynthetic process of immunological synapse formation Any positive regulation of glycoprotein biosynthetic process that is involved in immunological synapse formation. GO:2000527 regulation of myeloid dendritic cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000527 Any process that modulates the frequency, rate or extent of myeloid dendritic cell chemotaxis. GO:2000528 negative regulation of myeloid dendritic cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000528 Any process that stops, prevents or reduces the frequency, rate or extent of myeloid dendritic cell chemotaxis. GO:2000529 positive regulation of myeloid dendritic cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000529 Any process that activates or increases the frequency, rate or extent of myeloid dendritic cell chemotaxis. CHEBI:16359 cholic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16359 GO:2000520 regulation of immunological synapse formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000520 regulation of formation of immunological synapse Any process that modulates the frequency, rate or extent of immunological synapse formation. CHEBI:16357 3-(pyrazol-1-yl)-L-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16357 GO:2000521 negative regulation of immunological synapse formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000521 negative regulation of formation of immunological synapse Any process that stops, prevents or reduces the frequency, rate or extent of immunological synapse formation. CHEBI:16358 (R)-vicianin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16358 CHEBI:16355 1-iodo-2-methoxybenzene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16355 CHEBI:16356 3',5'-cyclic GMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16356 CHEBI:5385 gliotoxin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_5385 OBO:GOCHE_22587 substance with antiviral agent role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_22587 CHEBI:16353 sinapine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16353 CHEBI:16354 N-methylhydantoin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16354 CHEBI:16351 2-(alpha-D-mannosyl)-3-phosphoglyceric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16351 CHEBI:16352 4-hydroxy-1-pyrroline-2-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16352 CHEBI:5386 globin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_5386 CHEBI:16350 2'-deoxyribonucleoside 5'-diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16350 UBERON:0018113 left kidney interstitium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018113 left renal stroma|stroma of left kidney A kidney interstitium that is part of a left kidney. UBERON:0018114 right kidney interstitium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018114 right renal stroma|stroma of right kidney A kidney interstitium that is part of a right kidney. UBERON:0018111 muscle layer of rectum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018111 muscularis externa of rectum|muscular coat of rectum|rectal muscularis propria|tunica muscularis (rectum)|tunica muscularis recti A muscle layer that is part of the rectum UBERON:0018112 rectum smooth muscle tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018112 rectal smooth muscle tissue|smooth muscle of rectum|rectum smooth muscle Any portion of smooth muscle tissue that is part of the rectum GO:2000533 negative regulation of renal albumin absorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000533 Any process that stops, prevents or reduces the frequency, rate or extent of renal albumin absorption. GO:2000534 positive regulation of renal albumin absorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000534 Any process that activates or increases the frequency, rate or extent of renal albumin absorption. UBERON:0018119 left renal medulla interstitium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018119 medullary interstitial tissue of left kidney A renal medulla interstitium that is part of a left kidney. GO:2000535 regulation of entry of bacterium into host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000535 regulation of bacterial entry into host cell|regulation of invasion of bacteria into host cell Any process that modulates the frequency, rate or extent of entry of bacterium into host cell. CHEBI:31966 pelargonidin 3-O-(6-O-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31966 GO:2000536 negative regulation of entry of bacterium into host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000536 negative regulation of invasion of bacteria into host cell|negative regulation of bacterial entry into host cell Any process that stops, prevents or reduces the frequency, rate or extent of entry of bacterium into host cell. GO:2000537 regulation of B cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000537 Any process that modulates the frequency, rate or extent of B cell chemotaxis. CHEBI:31967 pelargonidin 3-O-beta-D-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31967 UBERON:0018117 left renal cortex interstitium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018117 cortical interstitial tissue of left kidney A renal cortex interstitium that is part of a left kidney. UBERON:0018118 right renal cortex interstitium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018118 cortical interstitial tissue of right kidney A renal cortex interstitium that is part of a right kidney. GO:2000538 positive regulation of B cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000538 Any process that activates or increases the frequency, rate or extent of B cell chemotaxis. CHEBI:31968 pelargonidin 3-O-rutinoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31968 CHEBI:31969 pelargonidin 3-O-rutinoside 5-O-beta-D-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31969 GO:2000539 regulation of protein geranylgeranylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000539 regulation of C-terminal protein geranylgeranylation|regulation of protein amino acid geranylgeranylation Any process that modulates the frequency, rate or extent of protein geranylgeranylation. UBERON:0018115 left renal pelvis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018115 renal pelvis of left kidney|pelvis of left ureter A renal pelvis that is part of a left ureter. UBERON:0018116 right renal pelvis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018116 pelvis of right kidney|pelvis of right ureter A renal pelvis that is part of a right ureter. PR:000003035 cellular tumor antigen p53 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000003035 P53|TP53|tumor suppressor p53|phosphoprotein p53|antigen NY-CO-13|Trp53 A protein that is a translation product of the human TP53 gene or a 1:1 ortholog thereof. CHEBI:16348 3-nitropropanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16348 CHEBI:16349 L-citrulline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16349 GO:2000530 obsolete positive regulation of regulation of insulin secretion involved in cellular response to glucose stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000530 positive regulation of regulation of insulin secretion involved in cellular response to glucose stimulus|positive regulation of regulation of insulin secretion in response to glucose OBSOLETE. Any process that activates or increases the frequency, rate or extent of regulation of insulin secretion involved in cellular response to glucose stimulus. CHEBI:16346 (S)-1-phenylethanol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16346 GO:2000531 obsolete regulation of fatty acid biosynthetic process by regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000531 OBSOLETE. Any process that modulates the frequency, rate or extent of the biosynthesis of fatty acids, by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter. CHEBI:16347 (R)-carnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16347 GO:2000532 regulation of renal albumin absorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000532 Any process that modulates the frequency, rate or extent of renal albumin absorption. CHEBI:16344 guanidinoacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16344 CHEBI:16345 3-sulfino-L-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16345 CHEBI:16342 L-5-carboxymethylhydantoin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16342 CHEBI:16343 phenylethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16343 GO:1905100 regulation of apoptosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905100 regulation of apoptosome formation Any process that modulates the frequency, rate or extent of apoptosome assembly. GO:1905101 negative regulation of apoptosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905101 down regulation of apoptosome assembly|downregulation of apoptosome assembly|down-regulation of apoptosome formation|negative regulation of apoptosome formation|down-regulation of apoptosome assembly|downregulation of apoptosome formation|inhibition of apoptosome assembly|down regulation of apoptosome formation|inhibition of apoptosome formation Any process that stops, prevents or reduces the frequency, rate or extent of apoptosome assembly. GO:1905102 positive regulation of apoptosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905102 upregulation of apoptosome assembly|up-regulation of apoptosome formation|activation of apoptosome formation|up regulation of apoptosome assembly|activation of apoptosome assembly|positive regulation of apoptosome formation|up regulation of apoptosome formation|up-regulation of apoptosome assembly|upregulation of apoptosome formation Any process that activates or increases the frequency, rate or extent of apoptosome assembly. GO:1905110 negative regulation of pulmonary blood vessel remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905110 down regulation of pulmonary blood vessel remodeling|downregulation of pulmonary blood vessel remodeling|down-regulation of pulmonary blood vessel remodeling|inhibition of pulmonary blood vessel remodeling Any process that stops, prevents or reduces the frequency, rate or extent of pulmonary blood vessel remodeling. GO:1905111 positive regulation of pulmonary blood vessel remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905111 upregulation of pulmonary blood vessel remodeling|up regulation of pulmonary blood vessel remodeling|activation of pulmonary blood vessel remodeling|up-regulation of pulmonary blood vessel remodeling Any process that activates or increases the frequency, rate or extent of pulmonary blood vessel remodeling. GO:1905112 obsolete regulation of centromere clustering at the mitotic nuclear envelope biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905112 regulation of centromere-SPB clustering|regulation of kinetochore clustering at SPB|regulation of kinetochore clustering at spindle pole body|regulation of rabl configuration|regulation of kinetochore localization at spindle pole body|regulation of kinetochore clustering at the old mitotic spindle pole body|regulation of centromere clustering at the nuclear periphery OBSOLETE. Any process that modulates the frequency, rate or extent of centromere clustering at the nuclear envelope. GO:1905113 obsolete positive regulation of centromere clustering at the mitotic nuclear envelope biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905113 upregulation of kinetochore clustering at spindle pole body|upregulation of kinetochore clustering at SPB|activation of rabl configuration|activation of kinetochore localization at spindle pole body|activation of kinetochore clustering at the old mitotic spindle pole body|upregulation of centromere clustering at the nuclear periphery|up regulation of centromere clustering at the nuclear envelope|activation of centromere clustering at the nuclear envelope|positive regulation of rabl configuration|up regulation of centromere-SPB clustering|up-regulation of kinetochore localization at spindle pole body|up-regulation of kinetochore clustering at the old mitotic spindle pole body|up regulation of rabl configuration|positive regulation of centromere-SPB clustering|up regulation of kinetochore clustering at SPB|up regulation of kinetochore clustering at spindle pole body|activation of centromere clustering at the nuclear periphery|up-regulation of centromere clustering at the nuclear periphery|positive regulation of kinetochore clustering at SPB|positive regulation of kinetochore clustering at spindle pole body|activation of centromere-SPB clustering|up-regulation of centromere clustering at the nuclear envelope|activation of kinetochore clustering at spindle pole body|upregulation of kinetochore clustering at the old mitotic spindle pole body|activation of kinetochore clustering at SPB|upregulation of kinetochore localization at spindle pole body|upregulation of rabl configuration|up-regulation of centromere-SPB clustering|positive regulation of centromere clustering at the nuclear periphery|up-regulation of kinetochore clustering at spindle pole body|up-regulation of kinetochore clustering at SPB|up regulation of centromere clustering at the nuclear periphery|upregulation of centromere clustering at the nuclear envelope|up regulation of kinetochore clustering at the old mitotic spindle pole body|up-regulation of rabl configuration|up regulation of kinetochore localization at spindle pole body|positive regulation of kinetochore localization at spindle pole body|upregulation of centromere-SPB clustering|positive regulation of kinetochore clustering at the old mitotic spindle pole body OBSOLETE. Any process that activates or increases the frequency, rate or extent of centromere clustering at the nuclear envelope. CHEBI:31915 nogalonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31915 GO:1905103 integral component of lysosomal membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1905103 integral to lysosomal membrane|integral component of lysosome membrane The component of the lysosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. CHEBI:16319 2-acetamido-5-oxopentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16319 GO:1905104 obsolete response to ouabain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905104 OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ouabain stimulus. GO:1905105 obsolete cellular response to ouabain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905105 OBSOLETE. Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ouabain stimulus. CHEBI:16317 3alpha-hydroxyglycyrrhetinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16317 GO:1905106 obsolete response to Dizocilpine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905106 OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Dizocilpine stimulus. CHEBI:16318 4-nitrocatechol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16318 GO:1905107 obsolete cellular response to Dizocilpine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905107 OBSOLETE. Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Dizocilpine stimulus. CHEBI:16315 morphinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16315 GO:1905108 guanosine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1905108 Interacting selectively and non-covalently with guanosine. GO:1905109 regulation of pulmonary blood vessel remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905109 Any process that modulates the frequency, rate or extent of pulmonary blood vessel remodeling. CHEBI:16313 D-proline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16313 CHEBI:16314 N-formylmethanofuran biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16314 CHEBI:16311 dCTP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16311 CHEBI:16312 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16312 CHEBI:16310 sulcatone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16310 UBERON:0018154 ligament of middle ear biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018154 A ligament that is part of a middle ear. UBERON:0018151 skin of upper lip biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018151 upper lip skin A zone of skin that is part of a upper lip. GO:1905120 cellular response to haloperidol biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_1905120 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a haloperidol stimulus. GO:1905121 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1905121 CHEBI:31923 novobiocic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31923 GO:1905122 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1905122 GO:1905123 regulation of glucosylceramidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905123 regulation of glucosylsphingosine beta-glucosidase activity|regulation of beta-glucocerebrosidase activity|regulation of ceramide glucosidase activity|regulation of GCase activity|regulation of beta-D-glucocerebrosidase activity|regulation of glucocerebrosidase activity|regulation of glucosphingosine glucosylhydrolase activity|regulation of psychosine hydrolase activity|regulation of GlcCer-beta-glucosidase activity|regulation of beta-glucosylceramidase activity|regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity|regulation of glucosylcerebrosidase activity|regulation of glucosylsphingosine beta-D-glucosidase activity|regulation of acid beta-glucosidase activity Any process that modulates the frequency, rate or extent of glucosylceramidase activity. GO:1905124 negative regulation of glucosylceramidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905124 down regulation of glucosylceramidase activity|inhibition of glucocerebrosidase activity|inhibition of acid beta-glucosidase activity|negative regulation of GCase activity|down regulation of glucosylsphingosine beta-glucosidase activity|inhibition of glucosphingosine glucosylhydrolase activity|downregulation of beta-glucocerebrosidase activity|negative regulation of beta-D-glucocerebrosidase activity|downregulation of glucosylceramidase activity|down-regulation of beta-D-glucocerebrosidase activity|inhibition of psychosine hydrolase activity|negative regulation of glucosylsphingosine beta-D-glucosidase activity|down-regulation of glucosylsphingosine beta-D-glucosidase activity|downregulation of glucosylsphingosine beta-glucosidase activity|down regulation of beta-glucocerebrosidase activity|down regulation of ceramide glucosidase activity|inhibition of beta-glucocerebrosidase activity|negative regulation of GlcCer-beta-glucosidase activity|down-regulation of GlcCer-beta-glucosidase activity|downregulation of beta-D-glucocerebrosidase activity|down regulation of glucocerebrosidase activity|downregulation of ceramide glucosidase activity|down-regulation of glucosylceramidase activity|down-regulation of beta-glucosylceramidase activity|inhibition of glucosylsphingosine beta-D-glucosidase activity|negative regulation of beta-glucosylceramidase activity|down-regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity|negative regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity|down-regulation of glucosylsphingosine beta-glucosidase activity|down-regulation of glucosylcerebrosidase activity|negative regulation of glucosylsphingosine beta-glucosidase activity|negative regulation of glucosylcerebrosidase activity|down regulation of glucosphingosine glucosylhydrolase activity|downregulation of glucocerebrosidase activity|down regulation of beta-D-glucocerebrosidase activity|down regulation of psychosine hydrolase activity|negative regulation of acid beta-glucosidase activity|down-regulation of acid beta-glucosidase activity|downregulation of GlcCer-beta-glucosidase activity|inhibition of beta-D-glucocerebrosidase activity|downregulation of glucosphingosine glucosylhydrolase activity|inhibition of glucosylceramidase activity|negative regulation of ceramide glucosidase activity|down-regulation of ceramide glucosidase activity|downregulation of psychosine hydrolase activity|down regulation of GlcCer-beta-glucosidase activity|downregulation of beta-glucosylceramidase activity|inhibition of glucosylsphingosine beta-glucosidase activity|downregulation of D-glucosyl-N-acylsphingosine glucohydrolase activity|inhibition of GlcCer-beta-glucosidase activity|downregulation of glucosylcerebrosidase activity|negative regulation of glucocerebrosidase activity|down-regulation of glucocerebrosidase activity|down regulation of glucosylsphingosine beta-D-glucosidase activity|negative regulation of beta-glucocerebrosidase activity|downregulation of acid beta-glucosidase activity|down-regulation of beta-glucocerebrosidase activity|down regulation of beta-glucosylceramidase activity|down regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity|inhibition of beta-glucosylceramidase activity|inhibition of ceramide glucosidase activity|down regulation of glucosylcerebrosidase activity|negative regulation of glucosphingosine glucosylhydrolase activity|down-regulation of glucosphingosine glucosylhydrolase activity|downregulation of glucosylsphingosine beta-D-glucosidase activity|inhibition of D-glucosyl-N-acylsphingosine glucohydrolase activity|inhibition of glucosylcerebrosidase activity|down regulation of acid beta-glucosidase activity|down-regulation of psychosine hydrolase activity|negative regulation of psychosine hydrolase activity Any process that stops, prevents or reduces the frequency, rate or extent of glucosylceramidase activity. GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905114 cell surface receptor linked signal transduction involved in cell-cell signaling|cell surface receptor linked signaling pathway involved in cell-cell signalling|cell surface receptor signaling pathway involved in cell-cell signalling|cell surface receptor linked signalling pathway involved in cell-cell signaling|cell surface receptor linked signalling pathway involved in cell-cell signalling|cell surface receptor linked signaling pathway involved in cell-cell signaling|cell surface receptor linked signal transduction involved in cell-cell signalling Any cell surface receptor signaling pathway that is involved in cell-cell signaling. CHEBI:16308 sucrose 6(F)-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16308 GO:1905115 regulation of lateral attachment of mitotic spindle microtubules to kinetochore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905115 Any process that modulates the frequency, rate or extent of lateral attachment of mitotic spindle microtubules to kinetochore. CHEBI:16309 4-sulfobenzoate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16309 GO:1905116 positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905116 up regulation of lateral attachment of mitotic spindle microtubules to kinetochore|activation of lateral attachment of mitotic spindle microtubules to kinetochore|up-regulation of lateral attachment of mitotic spindle microtubules to kinetochore|upregulation of lateral attachment of mitotic spindle microtubules to kinetochore Any process that activates or increases the frequency, rate or extent of lateral attachment of mitotic spindle microtubules to kinetochore. GO:1905117 regulation of ribonucleoside-diphosphate reductase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905117 regulation of class I ribonucleotide reductase activity|regulation of class III ribonucleotide reductase activity|regulation of class II ribonucleoside-diphosphate reductase activity|regulation of adenosylcobalamin-dependent ribonucleotide reductase activity|regulation of aerobic non-heme iron-dependent ribonucleotide reductase activity|regulation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity|regulation of ribonucleotide reductase activity|regulation of RNR|regulation of purine/pyrimidine nucleoside diphosphate reduction|regulation of ribonucleoside 5'-diphosphate reductase activity|regulation of class II ribonucleotide reductase activity|regulation of ribonucleotide diphosphate reductase activity|regulation of nucleoside diphosphate reductase activity Any process that modulates the frequency, rate or extent of ribonucleoside-diphosphate reductase activity. CHEBI:16307 anthocyanidin 3-O-beta-D-glucoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16307 GO:1905118 positive regulation of ribonucleoside-diphosphate reductase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905118 up-regulation of RNR|activation of ribonucleoside-diphosphate reductase activity|up regulation of class II ribonucleoside-diphosphate reductase activity|upregulation of adenosylcobalamin-dependent ribonucleotide reductase activity|upregulation of class III ribonucleotide reductase activity|upregulation of class I ribonucleotide reductase activity|upregulation of aerobic non-heme iron-dependent ribonucleotide reductase activity|up regulation of nucleoside diphosphate reductase activity|up-regulation of purine/pyrimidine nucleoside diphosphate reduction|up-regulation of ribonucleoside 5'-diphosphate reductase activity|upregulation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity|positive regulation of nucleoside diphosphate reductase activity|up regulation of ribonucleotide diphosphate reductase activity|up-regulation of ribonucleoside-diphosphate reductase activity|up-regulation of class II ribonucleotide reductase activity|positive regulation of ribonucleotide diphosphate reductase activity|activation of purine/pyrimidine nucleoside diphosphate reduction|upregulation of RNR|activation of nucleoside diphosphate reductase activity|activation of ribonucleoside 5'-diphosphate reductase activity|up regulation of class III ribonucleotide reductase activity|up regulation of adenosylcobalamin-dependent ribonucleotide reductase activity|up regulation of class I ribonucleotide reductase activity|upregulation of class II ribonucleoside-diphosphate reductase activity|up regulation of aerobic non-heme iron-dependent ribonucleotide reductase activity|activation of ribonucleotide diphosphate reductase activity|activation of class II ribonucleotide reductase activity|positive regulation of adenosylcobalamin-dependent ribonucleotide reductase activity|positive regulation of class I ribonucleotide reductase activity|positive regulation of class III ribonucleotide reductase activity|positive regulation of purine/pyrimidine nucleoside diphosphate reduction|up regulation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity|positive regulation of aerobic non-heme iron-dependent ribonucleotide reductase activity|positive regulation of ribonucleoside 5'-diphosphate reductase activity|upregulation of ribonucleoside-diphosphate reductase activity|up-regulation of nucleoside diphosphate reductase activity|up regulation of purine/pyrimidine nucleoside diphosphate reduction|positive regulation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity|up regulation of ribonucleoside 5'-diphosphate reductase activity|activation of class I ribonucleotide reductase activity|up-regulation of ribonucleotide diphosphate reductase activity|activation of class III ribonucleotide reductase activity|positive regulation of class II ribonucleotide reductase activity|activation of adenosylcobalamin-dependent ribonucleotide reductase activity|up regulation of RNR|activation of aerobic non-heme iron-dependent ribonucleotide reductase activity|up-regulation of class II ribonucleoside-diphosphate reductase activity|up regulation of class II ribonucleotide reductase activity|positive regulation of RNR|activation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity|upregulation of nucleoside diphosphate reductase activity|up-regulation of adenosylcobalamin-dependent ribonucleotide reductase activity|up-regulation of class I ribonucleotide reductase activity|up-regulation of class III ribonucleotide reductase activity|up regulation of ribonucleoside-diphosphate reductase activity|up-regulation of aerobic non-heme iron-dependent ribonucleotide reductase activity|activation of RNR|activation of class II ribonucleoside-diphosphate reductase activity|upregulation of purine/pyrimidine nucleoside diphosphate reduction|upregulation of ribonucleotide diphosphate reductase activity|upregulation of ribonucleoside 5'-diphosphate reductase activity|up-regulation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity|upregulation of class II ribonucleotide reductase activity|positive regulation of class II ribonucleoside-diphosphate reductase activity Any process that activates or increases the frequency, rate or extent of ribonucleoside-diphosphate reductase activity. CHEBI:16304 cob(II)alamin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16304 GO:1905119 response to haloperidol biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_1905119 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a haloperidol stimulus. CHEBI:16305 N(2),N(5)-dibenzoyl-L-ornithine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16305 CHEBI:16302 11-cis-retinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16302 CHEBI:16303 3-amino-L-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16303 CHEBI:16300 alpha-D-ribose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16300 UBERON:0018150 skin of lower lip biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018150 lower lip skin A zone of skin that is part of a lower lip. CHEBI:16301 nitrite biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16301 GO:0031902 late endosome membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031902 The lipid bilayer surrounding a late endosome. GO:0006946 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006946 GO:0031903 microbody membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031903 The lipid bilayer surrounding a microbody. GO:0006947 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006947 GO:0031900 chromoplast outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031900 The outer, i.e. cytoplasm-facing, lipid bilayer of the chromoplast envelope. GO:0006944 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006944 GO:0031901 early endosome membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031901 The lipid bilayer surrounding an early endosome. GO:0006945 obsolete nuclear fusion during karyogamy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006945 nuclear fusion during karyogamy OBSOLETE. The fusion of two haploid nuclei to form a single diploid nucleus, as seen in the yeast mating process. GO:0006942 regulation of striated muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006942 Any process that modulates the frequency, rate or extent of striated muscle contraction. GO:0006943 obsolete chemi-mechanical coupling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006943 chemi-mechanical coupling|mechanochemical coupling OBSOLETE. The conversion of chemical energy into mechanical work (as in the contraction of a muscle). GO:0006940 regulation of smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006940 Any process that modulates the frequency, rate or extent of smooth muscle contraction. GO:0006941 striated muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006941 sarcomeric muscle contraction A process in which force is generated within striated muscle tissue, resulting in the shortening of the muscle. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Striated muscle is a type of muscle in which the repeating units (sarcomeres) of the contractile myofibrils are arranged in registry throughout the cell, resulting in transverse or oblique striations observable at the level of the light microscope. GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000588 positive regulation of PDGF receptor-beta signaling pathway|positive regulation of platelet-derived growth factor receptor-beta signalling pathway|positive regulation of betaPDGF receptor signaling pathway|positive regulation of PDGFR-beta signaling pathway Any process that activates or increases the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway. CHEBI:65234 amidoxime biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65234 GO:2000589 regulation of metanephric mesenchymal cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000589 regulation of metanephric mesenchyme chemotaxis Any process that modulates the frequency, rate or extent of metanephric mesenchymal cell migration. GO:0031908 glyoxysomal lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031908 The volume enclosed by the membranes of a glyoxysome. GO:0031909 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031909 GO:0031906 late endosome lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031906 The volume enclosed by the membrane of a late endosome. GO:0031907 microbody lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031907 The volume enclosed by the membranes of a microbody. GO:0031904 endosome lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031904 NIF_Subcellular:sao1547508851 The volume enclosed by the membrane of an endosome. CHEBI:65232 EC 3.4.21.5 (thrombin) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65232 GO:0031905 early endosome lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031905 The volume enclosed by the membrane of an early endosome. GO:2000580 regulation of ATP-dependent microtubule motor activity, plus-end-directed biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000580 regulation of plus-end-directed microtubule motor activity|regulation of kinesin activity|regulation of plus-end-directed kinesin ATPase activity|regulation of kinesin ATP phosphohydrolase (plus-end-directed) Any process that modulates the frequency, rate or extent of ATP-dependent microtubule motor activity, plus-end-directed. GO:2000581 negative regulation of ATP-dependent microtubule motor activity, plus-end-directed biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000581 negative regulation of plus-end-directed microtubule motor activity|negative regulation of plus-end-directed kinesin ATPase activity|negative regulation of kinesin activity|negative regulation of kinesin ATP phosphohydrolase (plus-end-directed) Any process that stops, prevents or reduces the frequency, rate or extent of ATP-dependent microtubule motor activity, plus-end-directed. GO:2000582 positive regulation of ATP-dependent microtubule motor activity, plus-end-directed biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000582 positive regulation of plus-end-directed kinesin ATPase activity|positive regulation of plus-end-directed microtubule motor activity|positive regulation of kinesin activity|positive regulation of kinesin ATP phosphohydrolase (plus-end-directed) Any process that activates or increases the frequency, rate or extent of ATP-dependent microtubule motor activity, plus-end-directed. UBERON:0008867 trabecular network of bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008867 bone trabecula|bone trabeculae The network of intersecting plates and spicules in cancellous bone which form a meshwork of intercommunicating spaces filled with blood vessels and marrow; in mature bone, the trabeculae are aligned in parallel with the lines of major compressive or tensile force GO:2000583 regulation of platelet-derived growth factor receptor-alpha signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000583 regulation of PDGF receptor-alpha signaling pathway|regulation of platelet-derived growth factor receptor-alpha signalling pathway|regulation of alphaPDGF receptor signaling pathway|regulation of PDGFR-alpha signaling pathway Any process that modulates the frequency, rate or extent of platelet-derived growth factor receptor-alpha signaling pathway. GO:2000584 negative regulation of platelet-derived growth factor receptor-alpha signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000584 negative regulation of platelet-derived growth factor receptor-alpha signalling pathway|negative regulation of alphaPDGF receptor signaling pathway|negative regulation of PDGF receptor-alpha signaling pathway|negative regulation of PDGFR-alpha signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of platelet-derived growth factor receptor-alpha signaling pathway. GO:2000585 positive regulation of platelet-derived growth factor receptor-alpha signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000585 positive regulation of platelet-derived growth factor receptor-alpha signalling pathway|positive regulation of alphaPDGF receptor signaling pathway|positive regulation of PDGF receptor-alpha signaling pathway|positive regulation of PDGFR-alpha signaling pathway Any process that activates or increases the frequency, rate or extent of platelet-derived growth factor receptor-alpha signaling pathway. GO:2000586 regulation of platelet-derived growth factor receptor-beta signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000586 regulation of platelet-derived growth factor receptor-beta signalling pathway|regulation of PDGF receptor-beta signaling pathway|regulation of betaPDGF receptor signaling pathway|regulation of PDGFR-beta signaling pathway Any process that modulates the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway. GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000587 negative regulation of platelet-derived growth factor receptor-beta signalling pathway|negative regulation of PDGFR-beta signaling pathway|negative regulation of betaPDGF receptor signaling pathway|negative regulation of PDGF receptor-beta signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway. CHEBI:16298 D-mannitol 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16298 CHEBI:16299 dehydrocoformycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16299 CHEBI:16296 D-tryptophan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16296 UBERON:0008861 pyloric gastric gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008861 glandula pylorica|pyloric mucuous gland|pyloric antrum gland|pyloric gland The gastric glands in the pyloric region of the stomach; the pyloric glands secrete mucin, which coats the stomach and protects it, and hormones such as gastrin and enkephalin[MP]. CHEBI:16297 N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16297 CHEBI:16294 barbituric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16294 GO:0006948 induction by virus of host cell-cell fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006948 viral-induced membrane fusion|viral-induced host cell-cell fusion|induction by virus of cell-cell fusion in host|viral-induced cell-cell fusion The process of syncytia-forming cell-cell fusion, caused by a virus. GO:0006949 syncytium formation biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0006949 The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane. Syncytia are normally derived from single cells that fuse or fail to complete cell division. CHEBI:16295 alpha-D-glucosyl-(1->6)-alpha-D-glucosyl-(1->6)-alpha-D-glucosyl-(1->3')-1-alkyl-2-acylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16295 GO:0006957 complement activation, alternative pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006957 complement cascade, alternative pathway Any process involved in the activation of any of the steps of the alternative pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes. CHEBI:16292 D-arabinono-1,4-lactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16292 GO:0006958 complement activation, classical pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006958 complement cascade, classical pathway Any process involved in the activation of any of the steps of the classical pathway of the complement cascade which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes. GO:0006955 immune response biolink:BiologicalProcess go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0006955 Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. CHEBI:16290 5alpha-cholesta-7,24-dien-3beta-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16290 GO:0006956 complement activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006956 complement cascade|complement activity|complement response Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway. CHEBI:65240 1-alkyl-2-acyl-sn-glycero-3-phosphoserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65240 CHEBI:16291 1-alkyl-2-acetyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16291 GO:0006953 acute-phase response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006953 An acute inflammatory response that involves non-antibody proteins whose concentrations in the plasma increase in response to infection or injury of homeothermic animals. GO:0006954 inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006954 Wikipedia:Inflammation inflammation The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages. GO:0006951 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006951 GO:0006952 defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006952 defense/immunity protein activity|antimicrobial peptide activity|defence response|physiological defense response Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack. GO:2000599 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2000599 GO:0006950 response to stress biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate|goslim_plant|goslim_drosophila|goslim_metagenomics|goslim_aspergillus|goslim_generic|goslim_chembl|goslim_candida http://purl.obolibrary.org/obo/GO_0006950 response to biotic stress|response to abiotic stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). CHEBI:65248 L-tyrosiniumyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65248 CHEBI:41253 tetradecane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_41253 CHEBI:65243 1,2-dioctanoyl-sn-glycero-3-phospho-1D-myo-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65243 GO:2000591 positive regulation of metanephric mesenchymal cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000591 positive regulation of metanephric mesenchyme chemotaxis Any process that activates or increases the frequency, rate or extent of metanephric mesenchymal cell migration. GO:2000592 regulation of metanephric DCT cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000592 regulation of metanephric distal convoluted tubule cell differentiation Any process that modulates the frequency, rate or extent of metanephric DCT cell differentiation. GO:2000593 negative regulation of metanephric DCT cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000593 negative regulation of metanephric distal convoluted tubule cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of metanephric DCT cell differentiation. UBERON:0008856 stomach muscularis externa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008856 muscle layer of stomach|gastric muscularis|muscularis externa of stomach|tunica muscularis gastris|tunica muscularis (gaster) The smooth muscle layer of the stomach wall that functions to churn and mix food and gastric secretions as well as to move food along the digestive tract to the intestines GO:2000594 positive regulation of metanephric DCT cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000594 positive regulation of metanephric distal convoluted tubule cell differentiation Any process that activates or increases the frequency, rate or extent of metanephric DCT cell differentiation. GO:2000595 regulation of optic nerve formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000595 regulation of CN II formation|regulation of CN II biosynthesis Any process that modulates the frequency, rate or extent of optic nerve formation. CHEBI:65249 L-lysiniumyl(2+) group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65249 UBERON:0008858 pyloric canal biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008858 canalis pyloricus|canalis pyloricus The short narrow part of the stomach extending from the pyloric antrum to the pyloric sphincter GO:2000596 negative regulation of optic nerve formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000596 negative regulation of CN II biosynthesis|negative regulation of CN II formation Any process that stops, prevents or reduces the frequency, rate or extent of optic nerve formation. GO:2000597 positive regulation of optic nerve formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000597 positive regulation of CN II biosynthesis|positive regulation of CN II formation Any process that activates or increases the frequency, rate or extent of optic nerve formation. GO:2000598 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2000598 CHEBI:16289 beta-D-galactosyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16289 CHEBI:16287 UDP-N-acetyl-D-mannosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16287 CHEBI:16288 O-acetyl-L-homoserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16288 CHEBI:16285 phytanic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16285 CHEBI:16286 3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carbaldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16286 GO:0006959 humoral immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006959 Wikipedia:Humoral_immunity An immune response mediated through a body fluid. UBERON:0008851 ectoplacental cavity biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008851 epamniotic cavity|epamniotic cavity closed space within the ectoplacental cone, formed by the fusion of the parts of the amniotic fold that separate it from the amniotic cavity[MP]. a developmental cavity that exists in some mammals and is derived by division of the proamniotic space; it is further removed from the embryo than the amniotic cavity in some mammals CHEBI:16283 L-cystine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16283 CHEBI:16284 dATP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16284 GO:2000590 negative regulation of metanephric mesenchymal cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000590 negative regulation of metanephric mesenchyme chemotaxis Any process that stops, prevents or reduces the frequency, rate or extent of metanephric mesenchymal cell migration. GO:0006924 activation-induced cell death of T cells biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006924 activation-induced cell death of T-lymphocytes|activation-induced cell death of T-cells|antigen-driven apoptosis|activated T cell apoptosis|activation-induced cell death of T lymphocytes|AICD A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen and is triggered by T cell receptor stimulation and signals transmitted via various surface-expressed members of the TNF receptor family such as Fas ligand, Fas, and TNF and the p55 and p75 TNF receptors. GO:0006925 inflammatory cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006925 programmed cell death, inflammatory cells|apoptosis of inflammatory cells|programmed cell death of inflammatory cells by apoptosis|inflammatory cell apoptosis|killing of inflammatory cells|inflammatory cell programmed cell death by apoptosis Any apoptotic process in an inflammatory cell, any cell participating in the inflammatory response to a foreign substance e.g. neutrophil, macrophage. GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006922 cleavage of lamin|cleavage of lamin involved in execution phase of apoptosis OBSOLETE. The proteolytic degradation of lamins during apoptosis, leading to the irreversible breakdown of the nuclear lamina. CHEBI:65250 L-cysteiniumyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65250 GO:0006923 obsolete cleavage of cytoskeletal proteins involved in execution phase of apoptosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006923 cleavage of cytoskeletal proteins involved in apoptosis|apoptotic cleavage of cytoskeletal proteins|cleavage of cytoskeletal proteins involved in execution phase of apoptosis OBSOLETE. The proteolytic degradation of cytoskeletal proteins that contributes to apoptosis, leading to the collapse of cytoskeletal structures. GO:0006920 obsolete commitment to apoptosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006920 commitment to apoptosis OBSOLETE. (Was not defined before being made obsolete). GO:0006921 cellular component disassembly involved in execution phase of apoptosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006921 cellular component disassembly involved in apoptotic process|disassembly of cell structures|cellular component disassembly involved in apoptosis The breakdown of structures such as organelles, proteins, or other macromolecular structures during apoptosis. CHEBI:65256 antimicrobial food preservative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65256 CHEBI:65258 L-pyrrolysinium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65258 CHEBI:65259 GABA antagonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65259 CHEBI:41241 (R)-2-benzylsuccinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_41241 CHEBI:65254 LRH-1 agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65254 CHEBI:65255 food preservative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65255 UBERON:0008845 nonskeletal ligament biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008845 non-skeletal ligament|fibrous ligament A ligament that does not connect two skeletal elements. UBERON:0008846 skeletal ligament biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008846 articular ligament|articular larua|ligament|true ligament Dense regular connective tissue connecting two or more adjacent skeletal elements[VSAO,modified]. CHEBI:90218 gentamycin(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90218 CHEBI:90219 gentamycin 2''-phosphate dizwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90219 GO:0006928 movement of cell or subcellular component biolink:BiologicalProcess go-plus goslim_pir|gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0006928 cellular component motion|cell movement|cellular component movement The directed, self-propelled movement of a cell or subcellular component without the involvement of an external agent such as a transporter or a pore. GO:0006929 substrate-dependent cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006929 substrate-bound cell migration The orderly movement of a cell from one site to another along a substrate such as the extracellular matrix; the migrating cell forms a protrusion that attaches to the substrate. GO:0006926 obsolete virus-infected cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006926 virus-infected cell programmed cell death by apoptosis|programmed cell death of virus-infected cells by apoptosis|programmed cell death, virus-infected cells|virus-infected cell apoptosis|killing virus-infected cells|apoptosis of virus-infected cells|virus-infected cell apoptotic process OBSOLETE. Any apoptotic process in a cell infected with a virus. GO:0006927 obsolete transformed cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006927 programmed cell death of transformed cells by apoptosis|transformed cell programmed cell death by apoptosis|apoptosis of transformed cells|killing transformed cells|programmed cell death, transformed cells|transformed cell apoptosis OBSOLETE. Any apoptotic process in a transformed cell, a cell that has undergone changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm. GO:0006935 chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006935 Wikipedia:Chemotaxis taxis in response to chemical stimulus The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). GO:0006936 muscle contraction biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0006936 Wikipedia:Muscle_contraction A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. CHEBI:65260 3-hydroxyacyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65260 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006933 substrate-bound cell migration, cell release from substrate The disassembly of adhesions at the front and rear of a migrating cell. At the leading edge, adhesion disassembly accompanies the formation of new protrusions; at the cell rear, it promotes tail retraction. CHEBI:65261 purine deoxyribonucleotide(1-) residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65261 GO:0006934 substrate-bound cell migration, adhesion receptor recycling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006934 The directed movement of accumulated adhesion components such as integrins from the rear of a migrating cell toward the cell front, where they are available to form new protrusions and adhesions. CHEBI:65262 pyrimidine deoxyribonucleotide(1-) residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65262 GO:0006931 substrate-dependent cell migration, cell attachment to substrate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006931 substrate-bound cell migration, cell attachment to substrate The formation of adhesions that stabilize protrusions at the leading edge of a migrating cell; involves integrin activation, clustering, and the recruitment of structural and signaling components to nascent adhesions. GO:0006932 substrate-dependent cell migration, cell contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006932 substrate-bound cell migration, cell contraction The translocation of the cell body forward during cell migration, mediated by tractional force on its substrate and tension in the cortical cytoskeleton. Adhesions transmit propulsive forces and serve as traction points over which the cell moves. GO:0006930 substrate-dependent cell migration, cell extension biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006930 substrate-bound cell migration, cell extension The formation of a cell surface protrusion, such as a lamellipodium or filopodium, at the leading edge of a migrating cell. CHEBI:65263 cyclobutadithymidine(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65263 CHEBI:65264 dodecanoyl-pantetheine-4-phosphorylserine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65264 UBERON:0008835 hepatic diverticulum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008835 liver diverticulum|diverticulum hepaticum An out-pocket of thickened ventral foregut epithelium adjacent to the developing heart. Constitutes the first morphological sign of the embryonic liver. The anterior portion of the hepatic diverticulum gives rise to the liver and intrahepatic biliary tree, while the posterior portion forms the gall bladder and extrahepatic bile ducts. UBERON:0008836 liver bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008836 CHEBI:41237 benzyl benzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_41237 GO:0006939 smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006939 visceral muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length. GO:0006937 regulation of muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006937 Any process that modulates the frequency, rate or extent of muscle contraction. GO:0006938 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006938 GO:0006902 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006902 GO:0006903 vesicle targeting biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006903 The process in which vesicles are directed to specific destination membranes. Targeting involves coordinated interactions among cytoskeletal elements (microtubules or actin filaments), motor proteins, molecules at the vesicle membrane and target membrane surfaces, and vesicle cargo. CHEBI:16260 2-nitrophenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16260 GO:0006900 vesicle budding from membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006900 single-organism membrane budding|single organism membrane budding|vesicle budding|nonselective vesicle assembly|vesicle biosynthesis|membrane evagination|vesicle formation The evagination of a membrane, resulting in formation of a vesicle. GO:0006901 vesicle coating biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006901 vesicle coat assembly A protein coat is added to the vesicle to form the proper shape of the vesicle and to target the vesicle for transport to its destination. GO:2000544 regulation of endothelial cell chemotaxis to fibroblast growth factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000544 Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis to fibroblast growth factor. GO:2000545 negative regulation of endothelial cell chemotaxis to fibroblast growth factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000545 Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis to fibroblast growth factor. GO:2000546 positive regulation of endothelial cell chemotaxis to fibroblast growth factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000546 Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis to fibroblast growth factor. GO:2000547 regulation of dendritic cell dendrite assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000547 regulation of dendritic extension Any process that modulates the frequency, rate or extent of dendritic cell dendrite assembly. GO:2000548 negative regulation of dendritic cell dendrite assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000548 negative regulation of dendritic extension Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell dendrite assembly. UBERON:0018227 pulmonary lymphatic vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018227 lymphatic vessel of lung A lymphatic vessel that is part of a lung. GO:2000549 positive regulation of dendritic cell dendrite assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000549 positive regulation of dendritic extension Any process that activates or increases the frequency, rate or extent of dendritic cell dendrite assembly. UBERON:0018226 pulmonary part of lymphatic system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018226 pulmonary lymphatic chain|pulmonary lymphatic vasculature An organ system subdivision that is the part of the lymphoid system that includes the pulmonary lymphatic vessels. GO:2000540 negative regulation of protein geranylgeranylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000540 negative regulation of protein amino acid geranylgeranylation|negative regulation of C-terminal protein geranylgeranylation Any process that stops, prevents or reduces the frequency, rate or extent of protein geranylgeranylation. CHEBI:90238 beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer(d18:1/18:0) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90238 GO:2000541 positive regulation of protein geranylgeranylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000541 positive regulation of C-terminal protein geranylgeranylation|positive regulation of protein amino acid geranylgeranylation Any process that activates or increases the frequency, rate or extent of protein geranylgeranylation. NCBITaxon:436489 Saurischia organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_436489 NCBITaxon:436486 Dinosauria organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_436486 dinosaur|dinosaurs GO:2000542 negative regulation of gastrulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000542 Any process that stops, prevents or reduces the frequency, rate or extent of gastrulation. GO:2000543 positive regulation of gastrulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000543 Any process that activates or increases the frequency, rate or extent of gastrulation. CHEBI:16259 N-acetyl-L-phenylalanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16259 CL:0008046 extrafusal muscle fiber biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0008046 myofibra extrafusalis A skeletal muscle fiber that is innervated by alpha motor neuron and generates tension by contracting, thereby allowing for skeletal movement. These fibers make up the large mass of skeletal muscle tissue and are attached to bones by tendons. CHEBI:16256 2-methyl-3-oxopropanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16256 CHEBI:16257 5-O-(1-carboxyvinyl)-3-phosphoshikimic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16257 GO:0006908 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006908 CHEBI:90236 (2E,6E)-farnesyl monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90236 CHEBI:16254 11-cis-retinyl palmitate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16254 GO:0006909 phagocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006909 Wikipedia:Phagocytosis A vesicle-mediated transport process that results in the engulfment of external particulate material by phagocytes and their delivery to the lysosome. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles. CHEBI:16255 L-histidinol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16255 CHEBI:90230 prostaglandin E2 1-glyceryl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90230 CHEBI:16252 6-methoxymellein biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16252 GO:0006906 vesicle fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006906 Fusion of the membrane of a transport vesicle with its target membrane. GO:0006907 pinocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006907 Wikipedia:Pinocytosis single-organism pinocytosis|clathrin-independent pinocytosis|fluid-phase endocytosis An endocytosis process that results in the uptake of liquid material by cells from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, called pinosomes, formed by invagination of the plasma membrane. CHEBI:16253 2-(acetamidomethylidene)succinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16253 CHEBI:90231 alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer(d18:1/18:0) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90231 GO:0006904 vesicle docking involved in exocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006904 vesicle docking during exocytosis The initial attachment of a vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane, that contributes to exocytosis. CHEBI:16250 N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-D-galactosaminyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16250 CHEBI:90233 prostaglandin F2alpha 1-glyceryl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90233 CHEBI:16251 deaminohydroxyblasticidin S biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16251 GO:0006905 obsolete vesicle transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006905 vesicle transport OBSOLETE. (Was not defined before being made obsolete). GO:0006913 nucleocytoplasmic transport biolink:BiologicalProcess go-plus goslim_chembl|goslim_drosophila|goslim_generic|goslim_pombe http://purl.obolibrary.org/obo/GO_0006913 nucleocytoplasmic shuttling The directed movement of molecules between the nucleus and the cytoplasm. GO:0006914 autophagy biolink:BiologicalProcess go-plus goslim_chembl|goslim_pir|goslim_drosophila|goslim_generic|goslim_pombe http://purl.obolibrary.org/obo/GO_0006914 Wikipedia:Autophagy_(cellular) The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation. GO:0006911 phagocytosis, engulfment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006911 phagosome formation|phagosome biosynthesis The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis. CHEBI:65283 dodecanoyl-pantetheine-4-phosphorylserine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65283 GO:0006912 obsolete phagosome formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006912 phagosome formation OBSOLETE. (Was not defined before being made obsolete). GO:0006910 phagocytosis, recognition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006910 recognition of phagocytosed substance by phagocytic cell The initial step in phagocytosis involving adhesion to bacteria, immune complexes and other particulate matter, or an apoptotic cell and based on recognition of factors such as bacterial cell wall components, opsonins like complement and antibody or protein receptors and lipids like phosphatidyl serine, and leading to intracellular signaling in the phagocytosing cell. CHEBI:65280 N(omega)-methyl-argininium(1+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65280 GO:2000555 negative regulation of T-helper 1 cell cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000555 negative regulation of Th1 cell cytokine production Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 1 cell cytokine production. GO:2000556 positive regulation of T-helper 1 cell cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000556 positive regulation of Th1 cell cytokine production Any process that activates or increases the frequency, rate or extent of T-helper 1 cell cytokine production. GO:2000557 regulation of immunoglobulin production in mucosal tissue biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000557 regulation of antibody production in mucosal tissue Any process that modulates the frequency, rate or extent of immunoglobulin production in mucosal tissue. GO:2000558 positive regulation of immunoglobulin production in mucosal tissue biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000558 positive regulation of antibody production in mucosal tissue Any process that activates or increases the frequency, rate or extent of immunoglobulin production in mucosal tissue. GO:2000559 regulation of CD24 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000559 regulation of CD24 formation|regulation of CD24 biosynthesis|regulation of CD24 biosynthetic process|regulation of CD24 anabolism|regulation of CD24 synthesis Any process that modulates the frequency, rate or extent of CD24 biosynthetic process. CHEBI:65285 aliphatic amide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65285 CHEBI:65286 L-tyrosine-O-sulfate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65286 CHEBI:65287 cyclobutadithymidine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65287 UBERON:0008897 fin biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008897 fins An external projection of an aquatic animal as a fish used in propelling or guiding the body[BTO]. CHEBI:41218 mercaptoethanol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_41218 GO:2000550 negative regulation of B cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000550 Any process that stops, prevents or reduces the frequency, rate or extent of B cell chemotaxis. GO:2000551 regulation of T-helper 2 cell cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000551 regulation of Th2 cell cytokine production Any process that modulates the frequency, rate or extent of T-helper 2 cell cytokine production. CHEBI:90228 epoxypheophorbide a biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90228 GO:2000552 negative regulation of T-helper 2 cell cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000552 negative regulation of Th2 cell cytokine production Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 2 cell cytokine production. GO:2000553 positive regulation of T-helper 2 cell cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000553 positive regulation of Th2 cell cytokine production Any process that activates or increases the frequency, rate or extent of T-helper 2 cell cytokine production. CHEBI:16247 phospholipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16247 OBO:chebi#is_tautomer_of is tautomer of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/chebi#is_tautomer_of GO:2000554 regulation of T-helper 1 cell cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000554 regulation of Th1 cell cytokine production Any process that modulates the frequency, rate or extent of T-helper 1 cell cytokine production. CHEBI:90224 2-methylhexanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90224 CHEBI:16246 D-ribitol 5-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16246 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006919 caspase activation|activation of metacaspase activity|activation of caspase activity Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process. CHEBI:16243 quercetin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16243 CHEBI:16244 4-(trimethylammonio)butanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16244 GO:0006917 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006917 CHEBI:16241 aldehydo-D-arabinose 5-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16241 NCBITaxon:436491 Theropoda organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_436491 GO:0006918 obsolete induction of apoptosis by p53 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006918 induction of apoptosis by p53 OBSOLETE. (Was not defined before being made obsolete). NCBITaxon:436492 Coelurosauria organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_436492 GO:0006915 apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006915 Wikipedia:Apoptosis apoptosis|type I programmed cell death|signaling (initiator) caspase activity|caspase-dependent programmed cell death|commitment to apoptosis|apoptosis signaling|apoptotic programmed cell death|apoptotic cell death|cellular suicide|cell suicide|apoptosis activator activity|induction of apoptosis|apoptotic program|programmed cell death by apoptosis|induction of apoptosis by p53|activation of apoptosis A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. UBERON:0008895 splanchnocranium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008895 gill arch skeleton|visceral skeleton|visceral skeletal system|pharyngeal arch|viscerocranium|branchial arch skeleton|pharyngeal skeleton|visceral cranium|pharyngeal endoskeleton|pharyngeal arch skeleton Subdivision of endoskeleton derived from pharyngeal arches UBERON:0008896 post-hyoid pharyngeal arch biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008896 gill arch|branchial arches|gill bar|branchial bars|pharyngeal arch 3-7|visceral arches 3-7|branchial bar|branchial arch|gill arches 1-5 A pharyngeal arch that is posterior to the hyoid arch. i.e. any pharyngeal arch with a number 3 or higher. CHEBI:90222 (S)-2-methylbutanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90222 GO:0006916 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006916 CHEBI:16240 hydrogen peroxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16240 CHEBI:16281 3-(2-carboxyethenyl)-cis,cis-muconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16281 CHEBI:16282 2-ureidoglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16282 CHEBI:65294 phosphatidylcholine 28:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65294 CHEBI:65295 N-alkylphthalic monoamide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65295 CL:0008030 excitatory neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0008030 GO:2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000566 Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation. CHEBI:89268 2-hydroxyestradiol 3-methyl ether biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_89268 GO:2000567 regulation of memory T cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000567 Any process that modulates the frequency, rate or extent of memory T cell activation. GO:2000568 positive regulation of memory T cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000568 Any process that activates or increases the frequency, rate or extent of memory T cell activation. GO:2000569 regulation of T-helper 2 cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000569 regulation of Th2 cell activation Any process that modulates the frequency, rate or extent of T-helper 2 cell activation. CHEBI:65296 primary ammonium ion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65296 UBERON:0008886 pulmonary vascular system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008886 pulmonary circulatory system|pulmonary system The part of the cardiovascular system consisting of all pulmonary arteries and all pulmonary veins. UBERON:0008887 rectal venous plexus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008887 plexus venosus rectalis|hemorrhoidal plexus|plexus haemorrhoidalis|haemorrhoidal plexus The hemorrhoidal plexus (or rectal venous plexus) surrounds the rectum, and communicates in front with the vesical venous plexus in the male, and the uterovaginal plexus in the female. A free communication between the portal and systemic venous systems is established through the hemorrhoidal plexus. GO:2000560 positive regulation of CD24 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000560 positive regulation of CD24 synthesis|positive regulation of CD24 biosynthesis|positive regulation of CD24 formation|positive regulation of CD24 biosynthetic process|positive regulation of CD24 anabolism Any process that activates or increases the frequency, rate or extent of CD24 biosynthetic process. GO:2000561 regulation of CD4-positive, alpha-beta T cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000561 Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation. GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000562 Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation. CL:0008028 visual system neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0008028 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000563 Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation. CL:0008029 inhibitory neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0008029 GO:2000564 regulation of CD8-positive, alpha-beta T cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000564 Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation. GO:2000565 negative regulation of CD8-positive, alpha-beta T cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000565 Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation. CHEBI:16278 2-hydroxy-3-oxoadipic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16278 CL:0008024 pancreatic endocrine cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0008024 An endocrine cell that is part of the pancreas. CL:0008025 noradrenergic neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0008025 A neuron that release noradrenaline (noriphinephrine) as a neurotransmitter. CHEBI:16279 1-O-trans-cinnamoyl-beta-D-glucopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16279 CL:0008026 open tracheal system tracheocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0008026 An epithelial cell that is part of the epithelium of a tracheal tube in an open tracheal system, such as that found in insects. UBERON:0008881 rostral migratory stream biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008881 rostral migratory pathway|RMS Unique telencephalic subventricular zones that extend from the lateral ventricles into the olfactory bulbs. Newly produced GABAergic interneurons migrate along the RMS and settle in the bulb. CHEBI:16277 haloacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16277 CHEBI:16274 5,12-dihydroxanthommatin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16274 UBERON:0008882 spinal cord commissure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008882 The nerve fiber tracts that span the midline of the spinal cord UBERON:0008883 osteoid biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008883 prebone|prebone tissue|osteoid tissue|pre-bone Bone tissue that is an unmineralized bone matrix deposited by osteoblasts prior to the mineralization of bone tissue. CHEBI:16275 all-trans-octaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16275 CL:0008021 anterior lateral line ganglion neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0008021 UBERON:0008884 left putamen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008884 A putamen that is part of a left cerebral hemisphere. CL:0008022 endocardial cushion cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0008022 A mesenchymal cell of the endocardial cushion. These cells develop via an epithelial to mesenchymal transition when endocardial cells break cell-to-cell contacts and migrate into the cardiac jelly. Cells from this population form the heart septa and valves. UBERON:0008885 right putamen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008885 A putamen that is part of a right cerebral hemisphere. CHEBI:16273 2-amino-3-oxo-4-(phosphonooxy)butanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16273 CHEBI:16270 benzoylagmatine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16270 CHEBI:16271 2-exo-hydroxy-1,8-cineole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16271 CHEBI:90240 alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer(d18:1/18:0) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90240 GO:2000577 regulation of ATP-dependent microtubule motor activity, minus-end-directed biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000577 regulation of minus-end-directed kinesin ATPase activity|regulation of kinesin ATP phosphohydrolase (minus-end-directed)|regulation of minus-end-directed microtubule motor activity Any process that modulates the frequency, rate or extent of ATP-dependent microtubule motor activity, minus-end-directed. GO:2000578 negative regulation of ATP-dependent microtubule motor activity, minus-end-directed biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000578 negative regulation of minus-end-directed kinesin ATPase activity|negative regulation of kinesin ATP phosphohydrolase (minus-end-directed)|negative regulation of minus-end-directed microtubule motor activity Any process that stops, prevents or reduces the frequency, rate or extent of ATP-dependent microtubule motor activity, minus-end-directed. CHEBI:31887 N-acetyl-L-2-aminoadipic acid 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31887 GO:2000579 positive regulation of ATP-dependent microtubule motor activity, minus-end-directed biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000579 positive regulation of kinesin ATP phosphohydrolase (minus-end-directed)|positive regulation of minus-end-directed kinesin ATPase activity|positive regulation of minus-end-directed microtubule motor activity Any process that activates or increases the frequency, rate or extent of ATP-dependent microtubule motor activity, minus-end-directed. UBERON:0008876 hypodermis skeletal muscle layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008876 hypodermis muscle layer|hypodermal muscle layer|panniculus carnosus|superficial fascia muscular layer Any skeletal muscle organ in the hypodermis / superficial fascia GO:2000570 positive regulation of T-helper 2 cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000570 positive regulation of Th2 cell activation Any process that activates or increases the frequency, rate or extent of T-helper 2 cell activation. GO:2000571 regulation of interleukin-4-dependent isotype switching to IgE isotypes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000571 regulation of IL-4-dependent isotype switching to IgE isotypes Any process that modulates the frequency, rate or extent of interleukin-4-dependent isotype switching to IgE isotypes. GO:2000572 positive regulation of interleukin-4-dependent isotype switching to IgE isotypes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000572 positive regulation of IL-4-dependent isotype switching to IgE isotypes Any process that activates or increases the frequency, rate or extent of interleukin-4-dependent isotype switching to IgE isotypes. CL:0008039 lower motor neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0008039 The motor neurons of vertebrates that directly innervate skeletal muscles. They receive input from upper motor neurons. GO:2000573 positive regulation of DNA biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000573 positive regulation of DNA anabolism|positive regulation of DNA synthesis|positive regulation of DNA biosynthesis|positive regulation of DNA formation Any process that activates or increases the frequency, rate or extent of DNA biosynthetic process. CHEBI:31883 N-oleoyldopamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_31883 GO:2000574 regulation of microtubule motor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000574 regulation of dynein|regulation of kinetochore motor activity|regulation of axonemal motor activity|regulation of dynein ATPase activity|regulation of kinesin|regulation of kinesin motor activity Any process that modulates the frequency, rate or extent of microtubule motor activity. GO:2000575 negative regulation of microtubule motor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000575 negative regulation of dynein ATPase activity|negative regulation of kinesin|negative regulation of kinesin motor activity|negative regulation of axonemal motor activity|negative regulation of dynein|negative regulation of kinetochore motor activity Any process that stops, prevents or reduces the frequency, rate or extent of microtubule motor activity. CHEBI:16269 N,N-dimethylaniline biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16269 GO:2000576 positive regulation of microtubule motor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000576 positive regulation of kinetochore motor activity|positive regulation of dynein ATPase activity|positive regulation of axonemal motor activity|positive regulation of kinesin motor activity|positive regulation of dynein|positive regulation of kinesin Any process that activates or increases the frequency, rate or extent of microtubule motor activity. CHEBI:31885 N-acetyl-L-2-aminoadipic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31885 CHEBI:16267 (R)-4-hydroxymandelonitrile beta-D-glucoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16267 CHEBI:16268 nitroethane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16268 CHEBI:90246 alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-beta-D-GalNAc-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-Cer(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90246 CHEBI:16265 succinic semialdehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16265 UBERON:0008870 pulmonary alveolar parenchyma biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008870 The distinguishing cell types of the lung alveolar tissue, including pulmonary epithelial cells (pneumocytes), alveolar capillary endothelial cells, interstitial cells (fibroblasts) and alveolar macrophages CL:0008038 alpha motor neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0008038 alpha motoneuron A large, multipolar lower motor neuron of the brainstem and spinal cord that innervates the extrafusal muscle fibers of skeletal muscle and are directly responsible for initiating their contraction. While their cell bodies are in the CNS (in the anterior gray horn of the spinal cord), they are part of the somatic nervous system - a branch of the PNS. CHEBI:16266 2,3-bis-O-(geranylgeranyl)glycerol 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16266 CHEBI:16264 UDP-N-acetyl-alpha-D-glucosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16264 CL:0008033 decidual pericyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0008033 decidual perivascular cell A pericyte of the decidual vasculature. CHEBI:16261 chitosan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16261 UBERON:0008874 pulmonary acinus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008874 lobulus pulmonis primarius|primary pulmonary lobule|respiratory lobule|arbor alveolaris|acinus pulmonaris The part of the airway consisting of a respiratory bronchiole and all of its branches CL:0008034 mural cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0008034 Mural cells are pericytes and the vascular smooth muscle cells (vSMCs) of the microcirculation. GO:0031988 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031988 GO:1905090 negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905090 down regulation of parkin-mediated mitophagy in response to mitochondrial depolarization|negative regulation of Park2-mediated stimulation of mitophagy in response to mitochondrial depolarization|downregulation of parkin-mediated mitophagy in response to mitochondrial depolarization|negative regulation of PRKN-mediated stimulation of mitophagy in response to mitochondrial depolarization|down-regulation of parkin-mediated mitophagy in response to mitochondrial depolarization|inhibition of parkin-mediated mitophagy in response to mitochondrial depolarization Any process that stops, prevents or reduces the frequency, rate or extent of parkin-mediated mitophagy in response to mitochondrial depolarization. GO:0031989 bombesin receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031989 bombesin receptor signalling pathway The series of molecular signals generated as a consequence of a bombesin receptor binding to one of its physiological ligands. GO:0031986 proteinoplast biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031986 Wikipedia:Proteinoplast A leucoplast in which protein is stored. GO:0090282 positive regulation of transcription involved in G2/M transition of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090282 up-regulation of transcription involved in G2/M transition of mitotic cell cycle|positive regulation of G2/M-specific transcription in the mitotic cell cycle|activation of G2/M-specific transcription in the mitotic cell cycle|up-regulation of transcription from RNA polymerase II promoter during G2/M transition of the mitotic cell cycle|positive regulation of transcription from RNA polymerase II promoter during G2/M-phase of the mitotic cell cycle|up-regulation of G2/M-specific transcription in the mitotic cell cycle|activation of transcription from RNA polymerase II promoter during G2/M-phase of the mitotic cell cycle|activation of transcription involved in G2/M transition of mitotic cell cycle Any process that activates or increases the frequency, rate or extent of transcription of target genes that are transcribed as part of the G2/M transition of the mitotic cell cycle. GO:1905091 positive regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905091 upregulation of parkin-mediated mitophagy in response to mitochondrial depolarization|positive regulation of Park2-mediated stimulation of mitophagy in response to mitochondrial depolarization|up regulation of parkin-mediated mitophagy in response to mitochondrial depolarization|activation of parkin-mediated mitophagy in response to mitochondrial depolarization|positive regulation of PRKN-mediated stimulation of mitophagy in response to mitochondrial depolarization|up-regulation of parkin-mediated mitophagy in response to mitochondrial depolarization Any process that activates or increases the frequency, rate or extent of parkin-mediated mitophagy in response to mitochondrial depolarization. GO:0090283 regulation of protein glycosylation in Golgi biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090283 regulation of protein amino acid glycosylation in Golgi Any process that modulates the rate, frequency, or extent of the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus. GO:1905092 response to diosgenin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905092 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diosgenin stimulus. GO:0031987 locomotion involved in locomotory behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031987 locomotion during locomotory behaviour Self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement. GO:0090280 positive regulation of calcium ion import biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090280 positive regulation of transmembrane calcium influx Any process that increases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle. GO:0031984 organelle subcompartment biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031984 suborganelle compartment A compartment that consists of a lumen and an enclosing membrane, and is part of an organelle. GO:1905093 cellular response to diosgenin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905093 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diosgenin stimulus. GO:0031985 Golgi cisterna biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031985 NIF_Subcellular:sao561419532 Golgi lamellae Any of the thin, flattened membrane-bounded compartments that form the central portion of the Golgi complex. GO:1905094 regulation of apolipoprotein A-I-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905094 regulation of apolipoprotein A-I-mediated signalling pathway Any process that modulates the frequency, rate or extent of apolipoprotein A-I-mediated signaling pathway. GO:0090281 negative regulation of calcium ion import biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090281 negative regulation of transmembrane calcium influx Any process that decreases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle. GO:1905095 negative regulation of apolipoprotein A-I-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905095 downregulation of apolipoprotein A-I-mediated signalling pathway|down regulation of apolipoprotein A-I-mediated signalling pathway|inhibition of apolipoprotein A-I-mediated signalling pathway|down-regulation of apolipoprotein A-I-mediated signaling pathway|inhibition of apolipoprotein A-I-mediated signaling pathway|down-regulation of apolipoprotein A-I-mediated signalling pathway|negative regulation of apolipoprotein A-I-mediated signalling pathway|down regulation of apolipoprotein A-I-mediated signaling pathway|downregulation of apolipoprotein A-I-mediated signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of apolipoprotein A-I-mediated signaling pathway. GO:1905096 positive regulation of apolipoprotein A-I-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905096 up regulation of apolipoprotein A-I-mediated signaling pathway|activation of apolipoprotein A-I-mediated signaling pathway|upregulation of apolipoprotein A-I-mediated signalling pathway|up-regulation of apolipoprotein A-I-mediated signaling pathway|up-regulation of apolipoprotein A-I-mediated signalling pathway|activation of apolipoprotein A-I-mediated signalling pathway|upregulation of apolipoprotein A-I-mediated signaling pathway|positive regulation of apolipoprotein A-I-mediated signalling pathway|up regulation of apolipoprotein A-I-mediated signalling pathway Any process that activates or increases the frequency, rate or extent of apolipoprotein A-I-mediated signaling pathway. GO:1905097 regulation of guanyl-nucleotide exchange factor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905097 regulation of GDS|regulation of guanyl-nucleotide release factor activity|regulation of GNRP|regulation of GEF|regulation of guanyl-nucleotide releasing factor|regulation of GDP-dissociation stimulator activity Any process that modulates the frequency, rate or extent of guanyl-nucleotide exchange factor activity. GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905098 down regulation of guanyl-nucleotide release factor activity|down regulation of GDS|down regulation of guanyl-nucleotide exchange factor activity|inhibition of GEF|inhibition of guanyl-nucleotide exchange factor activity|downregulation of GDS|downregulation of guanyl-nucleotide release factor activity|downregulation of GNRP|down regulation of GNRP|negative regulation of GDP-dissociation stimulator activity|down-regulation of guanyl-nucleotide releasing factor|negative regulation of guanyl-nucleotide releasing factor|down-regulation of GDP-dissociation stimulator activity|negative regulation of guanyl-nucleotide release factor activity|down-regulation of guanyl-nucleotide release factor activity|down-regulation of GDS|negative regulation of GDS|down regulation of GEF|inhibition of GNRP|downregulation of GEF|inhibition of GDS|down-regulation of guanyl-nucleotide exchange factor activity|inhibition of guanyl-nucleotide release factor activity|downregulation of guanyl-nucleotide releasing factor|downregulation of GDP-dissociation stimulator activity|down regulation of GDP-dissociation stimulator activity|down regulation of guanyl-nucleotide releasing factor|inhibition of GDP-dissociation stimulator activity|inhibition of guanyl-nucleotide releasing factor|down-regulation of GEF|negative regulation of GEF|negative regulation of GNRP|down-regulation of GNRP|downregulation of guanyl-nucleotide exchange factor activity Any process that stops, prevents or reduces the frequency, rate or extent of guanyl-nucleotide exchange factor activity. GO:1905099 positive regulation of guanyl-nucleotide exchange factor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905099 upregulation of GDS|upregulation of guanyl-nucleotide release factor activity|positive regulation of GNRP|up-regulation of GEF|upregulation of guanyl-nucleotide exchange factor activity|up regulation of GNRP|up-regulation of GDP-dissociation stimulator activity|up-regulation of guanyl-nucleotide releasing factor|activation of guanyl-nucleotide releasing factor|activation of GDP-dissociation stimulator activity|up regulation of guanyl-nucleotide release factor activity|up regulation of GDS|activation of GDS|positive regulation of GDS|activation of guanyl-nucleotide release factor activity|positive regulation of guanyl-nucleotide release factor activity|upregulation of GEF|up-regulation of guanyl-nucleotide exchange factor activity|upregulation of GNRP|activation of guanyl-nucleotide exchange factor activity|positive regulation of guanyl-nucleotide releasing factor|positive regulation of GDP-dissociation stimulator activity|up regulation of GDP-dissociation stimulator activity|up regulation of guanyl-nucleotide releasing factor|up-regulation of GDS|up-regulation of guanyl-nucleotide release factor activity|up regulation of GEF|up-regulation of GNRP|activation of GEF|positive regulation of GEF|up regulation of guanyl-nucleotide exchange factor activity|upregulation of GDP-dissociation stimulator activity|upregulation of guanyl-nucleotide releasing factor|activation of GNRP Any process that activates or increases the frequency, rate or extent of guanyl-nucleotide exchange factor activity. GO:0016349 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016349 GO:0016345 female meiotic chromosome movement towards spindle pole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016345 female meiotic chromosome movement to spindle pole|chromosome movement towards spindle pole during female meiosis|female meiotic chromosome movement The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during female meiosis. GO:0016346 male meiotic chromosome movement towards spindle pole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016346 male meiotic chromosome movement to spindle pole|chromosome movement towards spindle pole during male meiosis|male meiotic chromosome movement The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during male meiosis. GO:0016347 obsolete calcium-independent cell adhesion molecule activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016347 calcium-independent cell adhesion molecule activity OBSOLETE. (Was not defined before being made obsolete). GO:0016348 imaginal disc-derived leg joint morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016348 The process in which the anatomical structures of an imaginal disc-derived leg joint are generated and organized. The leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner. An example of this is found in Drosophila melanogaster. GO:0090286 obsolete cytoskeletal anchoring at nuclear membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090286 OBSOLETE. The process in which cytoskeletal filaments are directly or indirectly linked to the nuclear membrane. GO:0031982 vesicle biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0031982 NIF_Subcellular:sao221389602|Wikipedia:Vesicle_(biology) membrane-bounded vesicle|membrane-enclosed vesicle Any small, fluid-filled, spherical organelle enclosed by membrane. GO:0016341 obsolete other collagen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016341 other collagen OBSOLETE. (Was not defined before being made obsolete). GO:0031983 vesicle lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031983 NIF_Subcellular:sao797538226 The volume enclosed by the membrane or protein that forms a vesicle. GO:0090287 regulation of cellular response to growth factor stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090287 Any process that modulates the rate, frequency, or extent of a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus. GO:0016342 catenin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016342 Complex of peripheral cytoplasmic proteins (alpha-, beta- and gamma-catenin) that interact with the cytoplasmic region of uvomorulin/E-cadherin to connect it to the actin cytoskeleton. GO:0090284 positive regulation of protein glycosylation in Golgi biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090284 positive regulation of protein amino acid glycosylation in Golgi Any process that increases the rate, frequency, or extent of the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus. GO:0016343 obsolete cytoskeletal anchoring activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016343 cytoskeletal anchoring activity OBSOLETE. The direct or indirect linkage of cytoskeletal filaments to the plasma membrane. GO:0031980 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031980 GO:0090285 negative regulation of protein glycosylation in Golgi biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090285 negative regulation of protein amino acid glycosylation in Golgi Any process that decreases the rate, frequency, or extent of the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus. GO:0016344 meiotic chromosome movement towards spindle pole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016344 meiotic chromosome movement|chromosome migration to spindle pole during meiosis|chromosome movement towards spindle pole during meiosis|meiotic chromosome movement to spindle pole The cell cycle process in which the directed movement of chromosomes from the center of the spindle towards the spindle poles takes place, mediated by the shortening of microtubules attached to the chromosomes. This occurs during meiosis. GO:0031981 nuclear lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031981 The volume enclosed by the nuclear inner membrane. GO:0090288 negative regulation of cellular response to growth factor stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090288 Any process that decreases the rate, frequency, or extent of a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus. GO:0016340 calcium-dependent cell-matrix adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016340 The binding of a cell to the extracellular matrix via adhesion molecules that require the presence of calcium for the interaction. GO:0090289 regulation of osteoclast proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090289 Any process that modulates the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population. GO:0031979 plasma membrane-derived thylakoid lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031979 plasma membrane thylakoid lumen The volume enclosed by a plasma membrane-derived thylakoid. GO:0090290 positive regulation of osteoclast proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090290 Any process that increases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population. GO:0031977 thylakoid lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031977 The volume enclosed by a thylakoid membrane. GO:0031978 plastid thylakoid lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031978 The volume enclosed by a plastid thylakoid membrane. GO:0031975 envelope biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031975 A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers, and may include a cell wall layer; also includes the space between layers. GO:0090293 nitrogen catabolite regulation of transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090293 regulation of transcription by nitrogen catabolites A transcription regulation process in which the presence of one nitrogen source leads to the modulation of the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources. GO:0031976 plastid thylakoid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031976 Any thylakoid within a plastid. GO:0090294 nitrogen catabolite activation of transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090294 positive regulation of transcription by nitrogen catabolites A transcription regulation process in which the presence of one nitrogen source leads to an increase in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources. GO:0090291 negative regulation of osteoclast proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090291 Any process that decreases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population. GO:0031973 chromoplast intermembrane space biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031973 chromoplast envelope lumen The region between the inner and outer lipid bilayers of a chromoplast envelope. GO:0090292 nuclear matrix anchoring at nuclear membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090292 nucleoskeleton anchoring at nuclear membrane The process in which the nuclear matrix, the dense fibrillar network lying on the inner side of the nuclear membrane, is directly or indirectly linked to the nuclear membrane. GO:0031974 membrane-enclosed lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031974 The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen. GO:0016356 obsolete organophosphorus susceptibility/resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016356 organophosphorus susceptibility/resistance OBSOLETE. (Was not defined before being made obsolete). GO:0016357 obsolete pyrethroid susceptibility/resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016357 pyrethroid susceptibility/resistance OBSOLETE. (Was not defined before being made obsolete). GO:0016358 dendrite development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016358 The process whose specific outcome is the progression of the dendrite over time, from its formation to the mature structure. GO:0016359 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016359 GO:0090297 positive regulation of mitochondrial DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090297 positive regulation of mitochondrial DNA synthesis Any process that increases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion. GO:0016352 obsolete insecticide susceptibility/resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016352 insecticide susceptibility/resistance OBSOLETE. (Was not defined before being made obsolete). GO:0031971 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031971 GO:0016353 obsolete carbamate susceptibility/resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016353 carbamate susceptibility/resistance OBSOLETE. (Was not defined before being made obsolete). GO:0090298 negative regulation of mitochondrial DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090298 negative regulation of mitochondrial DNA synthesis Any process that decreases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion. GO:0031972 chloroplast intermembrane space biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031972 chloroplast envelope lumen The region between the inner and outer lipid bilayers of a chloroplast envelope. GO:0090295 nitrogen catabolite repression of transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090295 nitrogen catabolite repression|negative regulation of transcription by nitrogen catabolites A transcription regulation process in which the presence of one nitrogen source leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources. GO:0016354 obsolete cyclodiene susceptibility/resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016354 cyclodiene susceptibility/resistance OBSOLETE. (Was not defined before being made obsolete). GO:0016355 obsolete DDT susceptibility/resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016355 DDT susceptibility/resistance OBSOLETE. (Was not defined before being made obsolete). GO:0090296 regulation of mitochondrial DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090296 regulation of mitochondrial DNA synthesis Any process that modulates the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion. GO:0031970 organelle envelope lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031970 organelle intermembrane space The region between the inner and outer lipid bilayers of an organelle envelope. GO:0090299 regulation of neural crest formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090299 Any process that modulates the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds. GO:0016350 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016350 GO:0016351 obsolete drug susceptibility/resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016351 drug susceptibility/resistance OBSOLETE. (Was not defined before being made obsolete). GO:0031968 organelle outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031968 The outer, i.e. cytoplasm-facing in a cellular organelle, lipid bilayer of an organelle envelope. GO:0031969 chloroplast membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031969 Wikipedia:Chloroplast_membrane Either of the lipid bilayers that surround a chloroplast and form the chloroplast envelope. GO:0031966 mitochondrial membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031966 NIF_Subcellular:sao1045389829 Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope. GO:0031967 organelle envelope biolink:CellularComponent go-plus goslim_mouse http://purl.obolibrary.org/obo/GO_0031967 A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes. GO:0090260 negative regulation of retinal ganglion cell axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090260 axon growth cone collapse Any process that decreases the frequency, rate, or extent of retinal ganglion cell axon guidance, the process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues. GO:0031964 beta-alanyl-histamine hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031964 carcinine hydrolase activity Catalysis of the reaction: N-beta-alanyl histamine + H2O = histamine + beta-alanine. GO:0031965 nuclear membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031965 NIF_Subcellular:sao1687101204 Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space. GO:0090261 positive regulation of inclusion body assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090261 Any process that increases the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body. GO:0031962 mineralocorticoid receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031962 Interacting selectively and non-covalently with a mineralocorticoid receptor. GO:0031963 cortisol receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031963 Combining with cortisol and transmitting the signal within the cell to trigger a change in cell activity or function. GO:0016327 apicolateral plasma membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016327 apical lateral plasma membrane The apical end of the lateral plasma membrane of epithelial cells. GO:0016328 lateral plasma membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016328 The portion of the plasma membrane at the lateral side of the cell. In epithelial cells, lateral plasma membranes are on the sides of cells which lie at the interface of adjacent cells. GO:0016329 obsolete apoptosis regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016329 apoptosis regulator activity OBSOLETE. The function held by products which directly regulate any step in the process of apoptosis. GO:0016323 basolateral plasma membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016323 The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis. GO:0016324 apical plasma membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016324 The region of the plasma membrane located at the apical end of the cell. GO:0016325 oocyte microtubule cytoskeleton organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016325 oocyte microtubule cytoskeleton organisation Formation and maintenance of a polarized microtubule array originating from a microtubule-organizing center (MTOC) in the oocyte. An example of this is found in Drosophila melanogaster. GO:0016326 obsolete kinesin motor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016326 kinesin motor activity OBSOLETE. The hydrolysis of ATP (and GTP) that drives the microtubular motor along microtubules. GO:0090264 regulation of immune complex clearance by monocytes and macrophages biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090264 Any process that modulates the rate, frequency, or extent of the process of immune complex clearance by monocytes or macrophages. GO:0031960 response to corticosteroid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031960 response to corticosteroid stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids. GO:0090265 positive regulation of immune complex clearance by monocytes and macrophages biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090265 Any process that increases the rate, frequency, or extent of the process of immune complex clearance by monocytes or macrophages. GO:0016320 endoplasmic reticulum membrane fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016320 ER membrane fusion The joining of 2 or more lipid bilayer membranes that surround the endoplasmic reticulum. GO:0031961 cortisol receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031961 Interacting selectively and non-covalently with a cortisol receptor. GO:0090262 regulation of transcription-coupled nucleotide-excision repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090262 Any process that modulates the frequency, rate, or extent of the nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway. GO:0016321 female meiosis chromosome segregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016321 The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a female. GO:0090263 positive regulation of canonical Wnt signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090263 positive regulation of canonical Wnt receptor signaling pathway|positive regulation of canonical Wnt receptor signalling pathway|positive regulation of catenin import into nucleus|positive regulation of canonical Wnt-activated signaling pathway|positive regulation of catenin protein nuclear translocation|positive regulation of Wnt receptor signaling pathway through beta-catenin Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. GO:0016322 neuron remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016322 axon pruning|neuronal remodeling The developmentally regulated remodeling of neuronal projections such as pruning to eliminate the extra dendrites and axons projections set up in early stages of nervous system development. GO:0090268 activation of mitotic cell cycle spindle assembly checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090268 Any process that starts the inactive process of a mitotic cell cycle spindle assembly checkpoint. GO:0090269 fibroblast growth factor production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0090269 The appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090266 Any process that modulates the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle. GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090267 Any process that increases the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle. GO:0031957 very long-chain fatty acid-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031957 Reactome:R-HSA-5695957|Reactome:R-HSA-5696007|Reactome:R-HSA-8875077 very-long-chain fatty acid-CoA ligase activity|very-long-chain-fatty-acid-CoA ligase activity|very-long-chain fatty acid activation Catalysis of the reaction: ATP + a very-long-chain fatty acid + CoA = AMP + diphosphate + an acyl-CoA; a very long-chain fatty acid is a fatty acid which has a chain length greater than C22. GO:0031958 corticosteroid receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031958 corticosteroid receptor signalling pathway Any series of molecular signals generated as a consequence of a corticosteroid binding to its receptor. GO:0031955 short-chain fatty acid-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031955 short-chain fatty acid activation|short-chain fatty-acid-CoA ligase activity|short-chain-fatty-acid-CoA ligase activity Catalysis of the reaction: ATP + a short-chain fatty acid + CoA = AMP + diphosphate + an acyl-CoA; short-chain fatty acids are fatty acids with a chain length of less than C6. GO:0031956 medium-chain fatty acid-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031956 EC:6.2.1.2|RHEA:48340 medium-chain fatty-acid-CoA ligase activity|medium-chain-fatty-acid-CoA ligase activity|medium-chain fatty acid activation Catalysis of the reaction: ATP + a medium-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA; a medium-chain fatty acid is any fatty acid with a chain length of between C6 and C12. GO:0090271 positive regulation of fibroblast growth factor production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090271 Any process that increases the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0031953 negative regulation of protein autophosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031953 downregulation of protein amino acid autophosphorylation|down regulation of protein amino acid autophosphorylation|inhibition of protein amino acid autophosphorylation|negative regulation of protein amino acid autophosphorylation|down-regulation of protein amino acid autophosphorylation Any process that stops, prevents or decreases the rate of the phosphorylation by a protein of one or more of its own residues. GO:0031954 positive regulation of protein autophosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031954 up regulation of protein amino acid autophosphorylation|upregulation of protein amino acid autophosphorylation|positive regulation of protein amino acid autophosphorylation|stimulation of protein amino acid autophosphorylation|up-regulation of protein amino acid autophosphorylation|activation of protein amino acid autophosphorylation Any process that activates or increases the frequency, rate or extent of the phosphorylation by a protein of one or more of its own residues. GO:0090272 negative regulation of fibroblast growth factor production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090272 Any process that decreases the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0031951 positive regulation of glucocorticoid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031951 upregulation of glucocorticoid catabolic process|stimulation of glucocorticoid catabolic process|up-regulation of glucocorticoid catabolic process|activation of glucocorticoid catabolic process|up regulation of glucocorticoid catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids. GO:0031952 regulation of protein autophosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031952 regulation of protein amino acid autophosphorylation Any process that modulates the frequency, rate or extent of addition of the phosphorylation by a protein of one or more of its own residues. GO:0090270 regulation of fibroblast growth factor production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090270 Any process that modulates the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0031959 mineralocorticoid receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031959 mineralocorticoid receptor signalling pathway Any series of molecular signals generated as a consequence of a mineralocorticoid binding to its receptor. GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016338 calcium-independent cell adhesion molecule activity The attachment of one cell to another cell via adhesion molecules that do not require the presence of calcium for the interaction. GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016339 calcium-dependent cell adhesion molecule activity The attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction. GO:0016334 establishment or maintenance of polarity of follicular epithelium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016334 Any cellular process that results in the specification, formation or maintenance of a polarized follicular epithelial sheet. GO:0016335 morphogenesis of larval imaginal disc epithelium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016335 The process in which the anatomical structures of a larval imaginal disc epithelium are generated and organized. GO:0016336 establishment or maintenance of polarity of larval imaginal disc epithelium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016336 Any cellular process that results in the specification, formation or maintenance of a polarized larval imaginal disc epithelium. GO:0016337 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016337 GO:0090275 negative regulation of somatostatin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090275 Any process that decreases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas. GO:0016330 second mitotic wave involved in compound eye morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016330 second mitotic wave during compound eye morphogenesis A discrete cell cycle in the third instar eye imaginal disc after progression of the morphogenetic furrow that contributes to compound eye morphogenesis. It is essential for generation of a sufficient pool of uncommitted cells to develop complete ommatidia. GO:0090276 regulation of peptide hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090276 Any process that modulates the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules. GO:0016331 morphogenesis of embryonic epithelium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016331 The process in which the anatomical structures of embryonic epithelia are generated and organized. GO:0031950 negative regulation of glucocorticoid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031950 down-regulation of glucocorticoid catabolic process|downregulation of glucocorticoid catabolic process|down regulation of glucocorticoid catabolic process|inhibition of glucocorticoid catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids. GO:0016332 establishment or maintenance of polarity of embryonic epithelium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016332 Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization of epithelial cells in an embryo. GO:0090273 regulation of somatostatin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090273 Any process that modulates the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas. GO:0016333 morphogenesis of follicular epithelium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016333 The process in which the anatomical structures of a follicular epithelium are generated and organized. GO:0090274 positive regulation of somatostatin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090274 Any process that increases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas. GO:0090279 regulation of calcium ion import biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090279 regulation of transmembrane calcium influx Any process that modulates the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle. CHEBI:507393 taurine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_507393 GO:0090277 positive regulation of peptide hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090277 Any process that increases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules. GO:0090278 negative regulation of peptide hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090278 Any process that decreases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules. GO:0031946 regulation of glucocorticoid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031946 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids. GO:0031947 negative regulation of glucocorticoid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031947 inhibition of glucocorticoid biosynthetic process|down regulation of glucocorticoid biosynthetic process|downregulation of glucocorticoid biosynthetic process|down-regulation of glucocorticoid biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids. GO:0031944 negative regulation of glucocorticoid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031944 negative regulation of glucocorticoid metabolism|downregulation of glucocorticoid metabolic process|down regulation of glucocorticoid metabolic process|inhibition of glucocorticoid metabolic process|down-regulation of glucocorticoid metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids. GO:0006988 obsolete unfolded protein response, cleavage of primary transcript encoding UFP-specific transcription factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006988 unfolded protein response, cleavage of primary transcript encoding UFP-specific transcription factor OBSOLETE. (Was not defined before being made obsolete). GO:0006989 obsolete unfolded protein response, ligation of mRNA encoding UFP-specific transcription factor by RNA ligase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006989 unfolded protein response, ligation of mRNA encoding UFP-specific transcription factor by RNA ligase OBSOLETE. (Was not defined before being made obsolete). GO:0031945 positive regulation of glucocorticoid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031945 up regulation of glucocorticoid metabolic process|upregulation of glucocorticoid metabolic process|stimulation of glucocorticoid metabolic process|up-regulation of glucocorticoid metabolic process|activation of glucocorticoid metabolic process|positive regulation of glucocorticoid metabolism Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids. GO:0006986 response to unfolded protein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006986 heat shock protein activity Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus. GO:0031942 i-AAA complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031942 Protease complex of the mitochondrial inner membrane whose catalytic residues lie on the intermembrane space side of the inner membrane; involved in mitochondrial protein turnover. Contains a subunit belonging to the AAA family of ATP-dependent metalloproteases. GO:0006987 obsolete activation of signaling protein activity involved in unfolded protein response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006987 unfolded protein response, activation of signalling protein kinase/endonuclease|unfolded protein response, activation of signaling protein activity|unfolded protein response, activation of signaling protein kinase/endonuclease OBSOLETE. The conversion of a specific protein, possessing protein kinase and endoribonuclease activities, to an active form as a result of signaling via the unfolded protein response. GO:0031943 regulation of glucocorticoid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031943 regulation of glucocorticoid metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids. GO:0031940 positive regulation of chromatin silencing at telomere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031940 upregulation of chromatin silencing at telomere|positive regulation of heterochromatic silencing at telomere|up regulation of chromatin silencing at telomere|activation of chromatin silencing at telomere|stimulation of chromatin silencing at telomere|up-regulation of chromatin silencing at telomere Any process that activates or increases the frequency, rate or extent of chromatin silencing at telomeres. GO:0006984 ER-nucleus signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006984 endoplasmic reticulum-nuclear signaling pathway|ER-nuclear signaling pathway|ER to nucleus signalling pathway|ER to nucleus signaling pathway|endoplasmic reticulum to nucleus signaling pathway|ER-nuclear signalling pathway Any series of molecular signals that conveys information from the endoplasmic reticulum to the nucleus, usually resulting in a change in transcriptional regulation. GO:0006985 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006985 GO:0031941 filamentous actin biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031941 Wikipedia:Actin F-actin A two-stranded helical polymer of the protein actin. GO:0006982 response to lipid hydroperoxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006982 response to LHPO Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid hydroperoxide stimulus. Lipid hydroperoxide is the highly reactive primary oxygenated products of polyunsaturated fatty acids. UBERON:0008817 thymus primordium endoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008817 An endoderm that is part of a thymus primordium. GO:0006983 ER overload response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006983 endoplasmic reticulum overload response|EOR-mediated activation of NF-kappaB|positive regulation of NF-kappaB transcription factor activity by EOR|EOR|positive regulation of NF-kappaB transcription factor activity by ER overload response|ER-overload response|EOR-mediated NF-kappaB activation The series of molecular signals generated by the accumulation of normal or misfolded proteins in the endoplasmic reticulum and leading to activation of transcription by NF-kappaB. GO:0006980 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006980 GO:0006981 obsolete activation of SoxR protein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006981 OBSOLETE. The conversion of the SoxR transcription factor to its active (oxidized) form. GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016309 EC:2.7.1.149|Reactome:R-HSA-1675776|RHEA:12280|Reactome:R-HSA-6811522|MetaCyc:2.7.1.149-RXN PIP4K|1-phosphatidylinositol-5-phosphate kinase|ATP:1-phosphatidyl-1D-myo-inositol-5-phosphate 4-phosphotransferase activity|type II PIP kinase activity Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate. GO:0031948 positive regulation of glucocorticoid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031948 up-regulation of glucocorticoid biosynthetic process|upregulation of glucocorticoid biosynthetic process|up regulation of glucocorticoid biosynthetic process|activation of glucocorticoid biosynthetic process|stimulation of glucocorticoid biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids. GO:0031949 regulation of glucocorticoid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031949 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids. GO:0016305 obsolete phosphatidylinositol 3-kinase activity, class II biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016305 PI3KC2|phosphatidylinositol 3-kinase activity, class II OBSOLETE. A phosphoinositide 3-kinase which can phosphorylate phosphatidylinositol and phosphatidylinositol-4-phosphate; the human form can phosphorylate phosphatidylinositol-4,5-bisphosphate in the presence of phosphatidylserine. GO:0016306 obsolete phosphatidylinositol 3-kinase activity, class III biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016306 phosphatidylinositol 3-kinase activity, class III OBSOLETE. A phosphoinositide 3-kinase which can only phosphorylate phosphatidylinositol. GO:0016307 phosphatidylinositol phosphate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016307 phosphatidylinositol monophosphate kinase activity Catalysis of the reaction: ATP + a phosphatidylinositol phosphate = ADP + a phosphatidylinositol bisphosphate. GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016308 RHEA:14425|Reactome:R-HSA-3772436|Reactome:R-HSA-8868066|MetaCyc:2.7.1.68-RXN|Reactome:R-HSA-1676082|KEGG_REACTION:R03469|EC:2.7.1.68 PIP5K|PtdIns(4)P-5-kinase activity|diphosphoinositide kinase activity|1-phosphatidylinositol-4-phosphate kinase, class IB|1-phosphatidylinositol-4-phosphate kinase, class IA|PIP kinase activity|1-phosphatidylinositol-4-phosphate kinase activity|ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 5-phosphotransferase activity|phosphatidylinositol-4-phosphate 5-kinase activity|phosphatidylinositol 4-phosphate kinase activity|type I PIP kinase activity Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ADP + 2 H(+). UBERON:0008823 neural tube derived brain biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008823 vertebrate brain A brain that develops_from a neural tube. GO:0016301 kinase activity biolink:MolecularActivity go-plus goslim_plant|goslim_drosophila|goslim_metagenomics|goslim_generic|goslim_chembl|goslim_yeast http://purl.obolibrary.org/obo/GO_0016301 Reactome:R-HSA-6788855|Reactome:R-HSA-6788867 phosphokinase activity Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. UBERON:0008824 duct of epididymis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008824 epididymis duct|epididymal duct Any duct branching of of the main epididymis duct. GO:0016302 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016302 GO:0016303 1-phosphatidylinositol-3-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016303 Reactome:R-HSA-1675961|EC:2.7.1.137|KEGG_REACTION:R03362|Reactome:R-HSA-1676024|Reactome:R-HSA-6798174|Reactome:R-HSA-109699|Reactome:R-HSA-1675939|RHEA:12709|Reactome:R-HSA-5672012|MetaCyc:1-PHOSPHATIDYLINOSITOL-3-KINASE-RXN ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase activity|type I phosphatidylinositol kinase activity|PI3-kinase activity|phosphatidylinositol 3-kinase activity, class I|Vps34p|phosphatidylinositol 3-kinase activity, class III|phosphatidylinositol 3-kinase activity, class II|type III phosphoinositide 3-kinase activity|PtdIns-3-kinase activity|1-phosphatidylinositol 3-kinase activity|PI3K|phosphatidylinositol 3-kinase, class I, catalyst activity Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ADP + 2 H(+). UBERON:0008826 pulmonary surfactant biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008826 type II pneumocyte secretion|lung surfactant|alveolar surfactant a substance formed by type II alveolar cells composed of surface-active lipoprotein complex (phospholipoprotein). GO:0016304 obsolete phosphatidylinositol 3-kinase activity, class I biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016304 phosphatidylinositol 3-kinase activity, class I OBSOLETE. A heterodimeric phosphoinositide 3-kinase which can phosphorylate phosphatidylinositol, phosphatidylinositol-4-phosphate or phosphatidylinositol-4,5-bisphosphate. Also possesses intrinsic protein kinase activity. GO:0016300 tRNA (uracil) methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016300 tRNA (uridine) methyltransferase activity Catalysis of the transfer of a methyl group from a donor to a uracil residue in a tRNA molecule. GO:0031935 regulation of chromatin silencing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031935 regulation of heterochromatic silencing Any process that affects the rate, extent or location of chromatin silencing. GO:0031936 negative regulation of chromatin silencing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031936 loss of chromatin silencing|down regulation of chromatin silencing|negative regulation of heterochromatic silencing|downregulation of chromatin silencing|down-regulation of chromatin silencing|inhibition of chromatin silencing Any process that stops, prevents, or reduces the frequency, rate or extent of chromatin silencing. GO:0006999 nuclear pore organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006999 nuclear pore complex organization and biogenesis|nuclear pore organization and biogenesis|nuclear pore organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear pore. GO:0031933 obsolete telomeric heterochromatin biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031933 telomeric chromatin OBSOLETE. Heterochromatic regions of the chromosome found at the telomeres. GO:0031934 mating-type region heterochromatin biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031934 Heterochromatic regions of the chromosome found at silenced mating-type loci. GO:0006997 nucleus organization biolink:BiologicalProcess go-plus goslim_pir|goslim_aspergillus|goslim_drosophila|goslim_yeast|goslim_candida http://purl.obolibrary.org/obo/GO_0006997 nucleus organization and biogenesis|nuclear organization and biogenesis|nuclear organisation|nuclear morphology|nuclear organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus. GO:0031931 TORC1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031931 Wikipedia:MTORC1 dTOR/dRaptor complex|nutrient sensitive complex|TORC 1 complex|dTORC1|mTORC1|TORC1|rapamycin and nutrient-sensitive TOR complex|TOR complex 1 A protein complex that contains at least TOR (target of rapamycin) and Raptor (regulatory-associated protein of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of S6K. In Saccharomyces, the complex contains Kog1p, Lst8p, Tco89p, and either Tor1p or Tor2p. GO:0031932 TORC2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031932 Wikipedia:MTORC1 rapamycin and nutrient-insensitive TOR complex|TORC 2 complex|mTORC2|TORC2|TOR complex 2 A protein complex that contains at least TOR (target of rapamycin) and Rictor (rapamycin-insensitive companion of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of PKB (also called AKT). In Saccharomyces, the complex contains Avo1p, Avo2p, Tsc11p, Lst8p, Bit61p, Slm1p, Slm2p, and Tor2p. GO:0006998 nuclear envelope organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006998 nuclear envelope organization and biogenesis|nuclear envelope organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope. GO:0006995 cellular response to nitrogen starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006995 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nitrogen. GO:0006996 organelle organization biolink:BiologicalProcess go-plus goslim_pir|goslim_aspergillus|goslim_candida http://purl.obolibrary.org/obo/GO_0006996 single-organism organelle organization|organelle organization and biogenesis|organelle organisation|single organism organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. GO:0031930 mitochondria-nucleus signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031930 mitochondria-nucleus signal transduction|mitochondrial signaling pathway|retrograde response|mitochondrial signalling pathway A series of molecular signals that forms a pathway of communication from the mitochondria to the nucleus and initiates cellular changes in response to changes in mitochondrial function. GO:0006993 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006993 GO:0006994 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006994 GO:0006991 response to sterol depletion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006991 sterol depletion response Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating deprivation of sterols. Sterols are a group of steroids characterized by the presence of one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. GO:0006992 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006992 GO:0031939 negative regulation of chromatin silencing at telomere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031939 negative regulation of heterochromatic silencing at telomere|downregulation of chromatin silencing at telomere|down-regulation of chromatin silencing at telomere|inhibition of chromatin silencing at telomere|down regulation of chromatin silencing at telomere Any process that stops, prevents, or reduces the frequency, rate or extent of chromatin silencing at telomeres. GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006990 unfolded protein response, activation of target gene transcription|unfolded protein response, target gene transcriptional activation|positive regulation of transcription of target genes involved in unfolded protein response|unfolded protein response, positive regulation of target gene transcription|unfolded protein response, up regulation of target gene transcription|unfolded protein response, stimulation of target gene transcription|unfolded protein response, upregulation of target gene transcription|unfolded protein response, up-regulation of target gene transcription The activation of genes whose promoters contain a specific sequence elements such as the unfolded protein response element (UPRE; consensus CAGCGTG) or the ER stress-response element (ERSE; CCAAN(N)9CCACG), as a result of signaling via the unfolded protein response. GO:0031937 positive regulation of chromatin silencing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031937 upregulation of chromatin silencing|positive regulation of heterochromatic silencing|up regulation of chromatin silencing|activation of chromatin silencing|stimulation of chromatin silencing|up-regulation of chromatin silencing Any process that activates or increases the frequency, rate or extent of chromatin silencing. GO:0031938 regulation of chromatin silencing at telomere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031938 regulation of heterochromatic silencing at telomere Any process that affects the rate, extent or location of chromatin silencing at telomeres. GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016316 Reactome:R-HSA-1676162|Reactome:R-HSA-1676164|EC:3.1.3.66|MetaCyc:3.1.3.66-RXN inositol polyphosphate 4-phosphatase type II activity|1-phosphatidyl-1D-myo-inositol-3,4-bisphosphate 4-phosphohydrolase activity Catalysis of the reaction: 1-phosphatidyl-myo-inositol 3,4-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate. UBERON:0008810 nasopalatine nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008810 nasopalatine nerves|nasopalatine|nervus nasopalatinus|naso-palatine nerve|Scarpa's nerve A branch of that maxillary nerve that innervates the mucous membrane of the hard palate. GO:0016318 ommatidial rotation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016318 The process in which photoreceptors are arranged in ommatidia in the dorsal and ventral fields to be mirror images. The polarity is established in the imaginal discs concurrently with cell fate specification. UBERON:0008811 intromittent organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008811 copulatory organ|aedeagus|penis An external organ of a male organism that is specialized to deliver sperm during copulation. Intromittent organs are found most often in terrestrial species, as most aquatic species fertilize their eggs externally, although there are exceptions[WP]. GO:0016319 mushroom body development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016319 The process whose specific outcome is the progression of the mushroom body over time, from its formation to the mature structure. The mushroom body is composed of the prominent neuropil structures of the insect central brain, thought to be crucial for olfactory associated learning. These consist mainly of a bulbous calyx and tightly packaged arrays of thin parallel fibers of the Kenyon cells. GO:0016312 inositol bisphosphate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016312 Reactome:R-HSA-6809561|RHEA:57840|Reactome:R-HSA-6809565 Catalysis of the reaction: myo-inositol bisphosphate + H2O = myo-inositol phosphate + phosphate. UBERON:0008814 pharyngeal arch system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008814 pharyngeal arch region|embryonic pharyngeal complex|pharyngeal arch complex|pharyngeal complex|pharyngeal arches and clefts|pharyngeal apparatus|pharyngeal system A transient embryonic complex that comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the stucture it contributes to are forming, which may include (depending on species) the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear[GO,modified]. GO:0016313 obsolete inositol-1,4,5-trisphosphate phosphatase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016313 inositol-1,4,5-trisphosphate phosphatase OBSOLETE. The removal of one of the phosphate groups from an inositol triphosphate to produce an inositol bisphosphate. GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016314 Reactome:R-HSA-199456|Reactome:R-HSA-2317387|EC:3.1.3.67|RHEA:25017|MetaCyc:3.1.3.67-RXN|Reactome:R-HSA-202237 PI(3,4,5)P3 3-phosphatase activity|1-phosphatidyl-1D-myo-inositol-3,4,5-trisphosphate 3-phosphohydrolase activity|PtdIns(3,4,5)P3 3-phosphatase activity|MMAC1|PI(3)P 3-phosphatase activity|phosphatidylinositol-3,4,5-trisphosphate 3-phosphohydrolase activity Catalysis of the reaction: phosphatidylinositol-3,4,5-trisphosphate + H2O = phosphatidylinositol-4,5-bisphosphate + phosphate. CHEBI:65207 vascular endothelial growth factor receptor antagonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65207 UBERON:0008816 embryonic head biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008816 A head that is part of a embryo. GO:0016315 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016315 CHEBI:5417 glucosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_5417 GO:0016310 phosphorylation biolink:BiologicalProcess go-plus goslim_chembl|goslim_metagenomics http://purl.obolibrary.org/obo/GO_0016310 Wikipedia:Phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. GO:0016311 dephosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016311 Wikipedia:Dephosphorylation The process of removing one or more phosphoric (ester or anhydride) residues from a molecule. CHEBI:5411 gluconapin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_5411 GO:0006968 cellular defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006968 intracellular defense response|intracellular defence response|cellular defence response A defense response that is mediated by cells. GO:0031924 vitamin B6 transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031924 vitamin B6 transporter activity Enables the transfer of any of the vitamin B6 compounds, pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate, from one side of a membrane to the other. GO:0031925 pyridoxal transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031925 pyridoxal transporter activity Enables the transfer of pyridoxal from one side of a membrane to the other. Pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate. GO:0006969 obsolete melanotic tumor response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006969 melanotic tumor response|melanotic mass response OBSOLETE. (Was not defined before being made obsolete). GO:0006966 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006966 GO:0031922 pyridoxamine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031922 The directed movement of pyridoxamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate. GO:0006967 positive regulation of antifungal peptide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006967 antifungal polypeptide induction|upregulation of antifungal peptide biosynthetic process|up regulation of antifungal peptide biosynthetic process|activation of antifungal peptide biosynthetic process|stimulation of antifungal peptide biosynthetic process|antifungal peptide induction|up-regulation of antifungal peptide biosynthetic process Any process that activates or increases the frequency, rate, or extent of antifungal peptide biosynthesis. GO:0031923 pyridoxine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031923 The directed movement of pyridoxine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate. GO:0006964 positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006964 up regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria|anti-Gram-negative bacterial polypeptide induction|upregulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria|stimulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria|up-regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria|activation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria|anti-Gram-negative bacterial peptide induction Any process that activates or increases the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria. GO:0031920 pyridoxal transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031920 The directed movement of pyridoxal into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate. GO:0031921 pyridoxal phosphate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031921 The directed movement of pyridoxal phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore; pyridoxal phosphate is pyridoxal phosphorylated at the hydroxymethyl group of C-5, and is the active form of vitamin B6. GO:0006965 positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006965 up regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria|upregulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria|anti-Gram-positive bacterial peptide induction|stimulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria|up-regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria|activation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria|anti-Gram-positive bacterial polypeptide induction Any process that activates or increases the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria. GO:0006962 male-specific antibacterial humoral response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006962 An immune response against bacteria, specific to males and mediated through a body fluid. GO:0006963 positive regulation of antibacterial peptide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006963 antibacterial polypeptide induction|upregulation of antibacterial peptide biosynthetic process|stimulation of antibacterial peptide biosynthetic process|activation of antibacterial peptide biosynthetic process|up-regulation of antibacterial peptide biosynthetic process|antibacterial peptide induction|up regulation of antibacterial peptide biosynthetic process Any process that activates or increases the frequency, rate, or extent of antibacterial peptide biosynthesis. GO:0006960 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006960 CHEBI:65212 polysaccharide derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65212 CHEBI:65213 2-acyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65213 GO:0006961 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006961 CHEBI:65214 2-acyl-sn-glycero-3-phosphoserine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65214 CHEBI:65215 1-acyl-2-alkyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65215 GO:0031928 pyridoxine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031928 pyridoxine transporter activity Enables the transfer of pyridoxine from one side of a membrane to the other. Pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate. GO:0031929 TOR signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031929 target of rapamycin signaling pathway|target of rapamycin signalling pathway|TOR signal transduction|TOR signaling pathway|TOR signaling cascade|TOR signalling pathway A series of molecular signals mediated by TOR (Target of rapamycin) proteins, members of the phosphoinositide (PI) 3-kinase related kinase (PIKK) family that act as serine/threonine kinases in response to nutrient availability or growth factors. GO:0031926 pyridoxal phosphate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031926 Enables the transfer of pyridoxal phosphate from one side of a membrane to the other. Pyridoxal phosphate is pyridoxal phosphorylated at the hydroxymethyl group of C-5, and is the active form of vitamin B6. CHEBI:65210 (2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65210 GO:0031927 pyridoxamine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031927 Enables the transfer of pyridoxamine from one side of a membrane to the other. Pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate. CHEBI:65211 1,2-dilauroyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65211 UBERON:0008805 gingival groove biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008805 tooth-gingiva interface|sulcus gingivalis|gingival sulcus|sulcus gingivalis The gingival sulcus is an area of potential space between a tooth and the surrounding gingival tissue and is lined by sulcular epithelium. The depth of the sulcus (Latin for groove) is bounded by two entities: apically by the gingival fibers of the connective tissue attachment and coronally by the free gingival margin. GO:0031913 contractile vacuole pore biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031913 Stable structure that regulates the flow of liquid between the contractile vacuole and the surrounding medium. GO:0006979 response to oxidative stress biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0006979 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. GO:0031914 negative regulation of synaptic plasticity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031914 down-regulation of synaptic plasticity|inhibition of synaptic plasticity|down regulation of synaptic plasticity|downregulation of synaptic plasticity A process that decreases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers. GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006977 positive regulation of cell cycle arrest by p53-mediated DNA damage response A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage and resulting in the stopping or reduction in rate of the cell cycle. GO:0031911 cytoproct biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031911 Stable, specialized structure for extrusion of waste by the cell into the surrounding medium. GO:0031912 oral apparatus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031912 Complex basket- or funnel-like structure used by the cell to collect food and channel it to the cytostome; includes specialized sub-structures made up of closely-spaced cilia and underlying basal bodies and fibrillar systems. GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006978 A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, resulting in the induction of the transcription of p21 (also known as WAF1, CIP1 and SDI1) or any equivalent protein, in response to the detection of DNA damage. GO:0006975 DNA damage induced protein phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006975 The widespread phosphorylation of various molecules, triggering many downstream processes, that occurs in response to the detection of DNA damage. GO:0031910 cytostome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031910 Wikipedia:Cytostome Stable, specialized structure for the ingestion of food by the cell into phagosomes. GO:0006976 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006976 GO:0006973 intracellular accumulation of glycerol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006973 The accumulation of glycerol within a cell, for example by increased glycerol biosynthesis combined with decreased permeability of the cell membrane to glycerol, in response to the detection of a hyperosmotic environment. GO:0006974 cellular response to DNA damage stimulus biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0006974 DNA damage response|response to genotoxic stress|cellular DNA damage response|response to DNA damage stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism. GO:0006971 hypotonic response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006971 hypo-osmotic response Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hypotonic environment, i.e. an environment with a lower concentration of solutes than the organism or cell. GO:0006972 hyperosmotic response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006972 HOG response|hypertonic response|response to hypertonicity Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell. GO:0031919 vitamin B6 transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031919 The directed movement of any of the vitamin B6 compounds -- pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate -- into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0006970 response to osmotic stress biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0006970 osmotic response|osmotic stress response Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. GO:0031917 negative regulation of synaptic metaplasticity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031917 inhibition of synaptic metaplasticity|down regulation of synaptic metaplasticity|downregulation of synaptic metaplasticity|down-regulation of synaptic metaplasticity A process that decreases synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require. GO:0031918 positive regulation of synaptic metaplasticity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031918 up-regulation of synaptic metaplasticity|upregulation of synaptic metaplasticity|up regulation of synaptic metaplasticity|activation of synaptic metaplasticity|stimulation of synaptic metaplasticity A process that increases synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require. CHEBI:65220 1-alkyl-2-acyl-sn-glycero-3-phosphoserine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65220 CHEBI:41275 1H-benzimidazole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_41275 GO:0031915 positive regulation of synaptic plasticity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031915 stimulation of synaptic plasticity|up-regulation of synaptic plasticity|upregulation of synaptic plasticity|up regulation of synaptic plasticity|activation of synaptic plasticity A process that increases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers. CHEBI:65221 1,2-dioctanoyl-sn-glycero-3-phospho-1D-myo-inositol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65221 GO:0031916 regulation of synaptic metaplasticity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031916 A process that modulates synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require. CHEBI:65228 3-hydroxyphenyl propanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65228 GO:1905010 positive regulation of L-lysine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905010 activation of L-lysine import into cell|up-regulation of L-lysine import into cell|positive regulation of L-lysine import into cell|upregulation of L-lysine import into cell|up regulation of L-lysine import into cell Any process that activates or increases the frequency, rate or extent of L-lysine import into cell. GO:1905011 transmembrane phosphate ion transport from cytosol to vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905011 vacuolar phosphate transport The directed movement of phosphate ions from the cytosol across the vacuolar membrane and into the vacuolar lumen. GO:1905012 regulation of 'de novo' NAD biosynthetic process from tryptophan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905012 regulation of de novo NAD biosynthetic process from tryptophan Any process that modulates the frequency, rate or extent of 'de novo' NAD biosynthetic process from tryptophan. GO:1905013 negative regulation of 'de novo' NAD biosynthetic process from tryptophan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905013 inhibition of de novo NAD biosynthetic process from tryptophan|down-regulation of 'de novo' NAD biosynthetic process from tryptophan|downregulation of 'de novo' NAD biosynthetic process from tryptophan|down-regulation of de novo NAD biosynthetic process from tryptophan|negative regulation of de novo NAD biosynthetic process from tryptophan|down regulation of 'de novo' NAD biosynthetic process from tryptophan|inhibition of 'de novo' NAD biosynthetic process from tryptophan|downregulation of de novo NAD biosynthetic process from tryptophan|down regulation of de novo NAD biosynthetic process from tryptophan Any process that stops, prevents or reduces the frequency, rate or extent of 'de novo' NAD biosynthetic process from tryptophan. GO:1905014 positive regulation of 'de novo' NAD biosynthetic process from tryptophan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905014 activation of 'de novo' NAD biosynthetic process from tryptophan|up-regulation of de novo NAD biosynthetic process from tryptophan|up regulation of 'de novo' NAD biosynthetic process from tryptophan|activation of de novo NAD biosynthetic process from tryptophan|positive regulation of de novo NAD biosynthetic process from tryptophan|up regulation of de novo NAD biosynthetic process from tryptophan|upregulation of 'de novo' NAD biosynthetic process from tryptophan|upregulation of de novo NAD biosynthetic process from tryptophan|up-regulation of 'de novo' NAD biosynthetic process from tryptophan Any process that activates or increases the frequency, rate or extent of 'de novo' NAD biosynthetic process from tryptophan. GO:0090448 glucosinolate:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090448 glucosinolate:hydrogen symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucosinolate(out) + H+(out) = glucosinolate(in) + H+(in). GO:1905004 picolinic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905004 picolinic acid biosynthesis|picolinate biosynthetic process|picolinate biosynthesis|picolinic acid anabolism|picolinic acid synthesis|picolinic acid formation The chemical reactions and pathways resulting in the formation of picolinic acid. GO:0090449 phloem glucosinolate loading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090449 The process of loading glucosinolates into the sieve tube or companion cell of the phloem for long distance transport from source to sink. GO:1905005 regulation of epithelial to mesenchymal transition involved in endocardial cushion formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905005 Any process that modulates the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation. GO:0090446 negative regulation of nematode larval development, heterochronic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090446 Any process that modulates the consistent predetermined time point at which a nematode larva progresses from an initial condition to a later condition and decreases the rate at which this time point is reached. GO:1905006 negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905006 downregulation of epithelial to mesenchymal transition involved in endocardial cushion formation|down regulation of epithelial to mesenchymal transition involved in endocardial cushion formation|inhibition of epithelial to mesenchymal transition involved in endocardial cushion formation|down-regulation of epithelial to mesenchymal transition involved in endocardial cushion formation Any process that stops, prevents or reduces the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation. GO:0090447 glycerol-3-phosphate 2-O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090447 Catalysis of the reaction: an acyl-CoA + sn-glycerol 3-phosphate = CoA + a 2-acyl-sn-glycerol 3-phosphate. GO:1905007 positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905007 up regulation of epithelial to mesenchymal transition involved in endocardial cushion formation|upregulation of epithelial to mesenchymal transition involved in endocardial cushion formation|activation of epithelial to mesenchymal transition involved in endocardial cushion formation|up-regulation of epithelial to mesenchymal transition involved in endocardial cushion formation Any process that activates or increases the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation. GO:1905008 regulation of L-lysine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905008 regulation of L-lysine import into cell|regulation of lysine import|regulation of lysine uptake Any process that modulates the frequency, rate or extent of L-lysine import into cell. GO:1905009 negative regulation of L-lysine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905009 inhibition of L-lysine import into cell|negative regulation of lysine uptake|negative regulation of L-lysine import into cell|down regulation of L-lysine import into cell|downregulation of L-lysine import into cell|negative regulation of lysine import|down-regulation of L-lysine import into cell Any process that stops, prevents or reduces the frequency, rate or extent of L-lysine import into cell. GO:0090440 abscisic acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090440 abscisic acid transporter activity Enables the transfer of abscisic acid from one side of a membrane to the other. GO:0090441 trehalose biosynthesis in response to heat stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090441 trehalose biosynthetic process in response to heat stress The chemical reactions and pathways resulting in the formation of trehalose that occur as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism. GO:0090444 regulation of nematode larval development, heterochronic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090444 Any process that modulates the consistent predetermined time point at which a nematode larva progresses from an initial condition to a later condition and the rate at which this time point is reached. GO:0090445 positive regulation of nematode larval development, heterochronic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090445 Any process that modulates the consistent predetermined time point at which a nematode larva progresses from an initial condition to a later condition and increases the rate at which this time point is reached. GO:0090442 trehalose catabolism in response to heat stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090442 trehalose catabolic process in response to heat stress The chemical reactions and pathways resulting in the degradation of trehalose that occur as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism. GO:0090443 FAR/SIN/STRIPAK complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090443 SIP complex|STRIPAK signalling complex|FAR complex|striatin interacting phosphatase and kinase complex A conserved protein phosphatase type 2A complex which contains a protein phosphatase type 2A, a protein phosphatase regulatory subunit, a striatin, an FHA domain protein and other subunits (at least six proteins). In fission yeast this complex negatively regulate the septation initiation network at the spindle pole body. GO:1905020 positive regulation of methionine-tRNA ligase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905020 positive regulation of methionine translase activity|upregulation of methionyl-transfer ribonucleic acid synthetase activity|upregulation of L-methionine:tRNAMet ligase (AMP-forming)|upregulation of MetRS activity|up-regulation of methionine-tRNA ligase activity|activation of methionyl-tRNA synthetase activity|up-regulation of methionyl-tRNA synthetase activity|up-regulation of methionyl-transfer ribonucleate synthetase activity|up-regulation of methionyl-transfer RNA synthetase activity|activation of methionyl-transfer RNA synthetase activity|up regulation of methionyl-transfer ribonucleic acid synthetase activity|up-regulation of methionine translase activity|up regulation of L-methionine:tRNAMet ligase (AMP-forming)|activation of methionyl-transfer ribonucleic acid synthetase activity|up-regulation of MetRS activity|activation of MetRS activity|positive regulation of methionyl-transfer ribonucleic acid synthetase activity|activation of L-methionine:tRNAMet ligase (AMP-forming)|positive regulation of L-methionine:tRNAMet ligase (AMP-forming)|upregulation of methionine-tRNA ligase activity|upregulation of methionyl-transfer ribonucleate synthetase activity|positive regulation of methionyl-tRNA synthetase activity|positive regulation of methionyl-transfer RNA synthetase activity|upregulation of methionine translase activity|up regulation of methionyl-tRNA synthetase activity|up regulation of methionyl-transfer RNA synthetase activity|positive regulation of MetRS activity|up-regulation of methionyl-transfer ribonucleic acid synthetase activity|up-regulation of L-methionine:tRNAMet ligase (AMP-forming)|up regulation of MetRS activity|up regulation of methionine-tRNA ligase activity|up regulation of methionyl-transfer ribonucleate synthetase activity|activation of methionine-tRNA ligase activity|activation of methionyl-transfer ribonucleate synthetase activity|positive regulation of methionyl-transfer ribonucleate synthetase activity|up regulation of methionine translase activity|upregulation of methionyl-tRNA synthetase activity|activation of methionine translase activity|upregulation of methionyl-transfer RNA synthetase activity Any process that activates or increases the frequency, rate or extent of methionine-tRNA ligase activity. GO:1905021 regulation of threonine-tRNA ligase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905021 regulation of threonyl ribonucleic synthetase activity|regulation of TRS|regulation of threonyl-transfer ribonucleate synthetase activity|regulation of threonine translase activity|regulation of threonyl-tRNA synthetase activity|regulation of threonyl-transfer RNA synthetase activity|regulation of threonine-transfer ribonucleate synthetase activity|regulation of threonyl-transfer ribonucleic acid synthetase activity|regulation of L-threonine:tRNAThr ligase (AMP-forming) Any process that modulates the frequency, rate or extent of threonine-tRNA ligase activity. GO:1905022 negative regulation of threonine-tRNA ligase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905022 downregulation of threonyl ribonucleic synthetase activity|downregulation of threonine-tRNA ligase activity|down regulation of TRS|downregulation of threonyl-transfer ribonucleate synthetase activity|down regulation of threonyl ribonucleic synthetase activity|downregulation of TRS|downregulation of threonine translase activity|down regulation of threonine-tRNA ligase activity|down regulation of threonyl-tRNA synthetase activity|inhibition of threonyl ribonucleic synthetase activity|down regulation of threonyl-transfer RNA synthetase activity|down regulation of threonyl-transfer ribonucleate synthetase activity|inhibition of threonine-tRNA ligase activity|down regulation of threonine-transfer ribonucleate synthetase activity|down-regulation of threonyl-transfer ribonucleic acid synthetase activity|negative regulation of threonyl-transfer ribonucleic acid synthetase activity|inhibition of threonyl-transfer ribonucleate synthetase activity|downregulation of threonyl-tRNA synthetase activity|down-regulation of L-threonine:tRNAThr ligase (AMP-forming)|negative regulation of L-threonine:tRNAThr ligase (AMP-forming)|down regulation of threonine translase activity|downregulation of threonyl-transfer RNA synthetase activity|inhibition of threonine translase activity|downregulation of threonine-transfer ribonucleate synthetase activity|negative regulation of TRS|down-regulation of TRS|downregulation of threonyl-transfer ribonucleic acid synthetase activity|down-regulation of threonyl-tRNA synthetase activity|negative regulation of threonyl-tRNA synthetase activity|downregulation of L-threonine:tRNAThr ligase (AMP-forming)|down-regulation of threonyl-transfer RNA synthetase activity|negative regulation of threonyl-transfer RNA synthetase activity|negative regulation of threonine-transfer ribonucleate synthetase activity|down-regulation of threonine-transfer ribonucleate synthetase activity|down regulation of threonyl-transfer ribonucleic acid synthetase activity|down regulation of L-threonine:tRNAThr ligase (AMP-forming)|negative regulation of threonyl ribonucleic synthetase activity|inhibition of threonyl-transfer ribonucleic acid synthetase activity|down-regulation of threonyl ribonucleic synthetase activity|down-regulation of threonine-tRNA ligase activity|inhibition of L-threonine:tRNAThr ligase (AMP-forming)|inhibition of threonyl-tRNA synthetase activity|negative regulation of threonyl-transfer ribonucleate synthetase activity|down-regulation of threonyl-transfer ribonucleate synthetase activity|inhibition of TRS|inhibition of threonyl-transfer RNA synthetase activity|inhibition of threonine-transfer ribonucleate synthetase activity|down-regulation of threonine translase activity|negative regulation of threonine translase activity Any process that stops, prevents or reduces the frequency, rate or extent of threonine-tRNA ligase activity. GO:1905023 positive regulation of threonine-tRNA ligase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905023 up regulation of threonyl ribonucleic synthetase activity|positive regulation of threonyl-transfer ribonucleate synthetase activity|up regulation of threonine-tRNA ligase activity|upregulation of TRS|up regulation of threonyl-transfer ribonucleate synthetase activity|positive regulation of threonine translase activity|up-regulation of threonyl-transfer ribonucleic acid synthetase activity|up-regulation of L-threonine:tRNAThr ligase (AMP-forming)|activation of threonyl-transfer ribonucleic acid synthetase activity|up regulation of threonine translase activity|upregulation of threonyl-tRNA synthetase activity|upregulation of threonyl-transfer RNA synthetase activity|activation of L-threonine:tRNAThr ligase (AMP-forming)|upregulation of threonine-transfer ribonucleate synthetase activity|upregulation of threonyl ribonucleic synthetase activity|up regulation of TRS|upregulation of threonine-tRNA ligase activity|upregulation of threonyl-transfer ribonucleate synthetase activity|positive regulation of TRS|up regulation of threonyl-tRNA synthetase activity|upregulation of threonine translase activity|positive regulation of threonyl-transfer ribonucleic acid synthetase activity|up regulation of threonyl-transfer RNA synthetase activity|positive regulation of L-threonine:tRNAThr ligase (AMP-forming)|up regulation of threonine-transfer ribonucleate synthetase activity|activation of threonyl-tRNA synthetase activity|positive regulation of threonyl-tRNA synthetase activity|up regulation of threonyl-transfer ribonucleic acid synthetase activity|up regulation of L-threonine:tRNAThr ligase (AMP-forming)|activation of TRS|activation of threonyl-transfer RNA synthetase activity|positive regulation of threonyl-transfer RNA synthetase activity|positive regulation of threonine-transfer ribonucleate synthetase activity|activation of threonine-transfer ribonucleate synthetase activity|up-regulation of threonyl ribonucleic synthetase activity|up-regulation of threonine-tRNA ligase activity|activation of threonyl ribonucleic synthetase activity|up-regulation of threonyl-transfer ribonucleate synthetase activity|activation of threonine-tRNA ligase activity|activation of threonyl-transfer ribonucleate synthetase activity|up-regulation of TRS|up-regulation of threonine translase activity|activation of threonine translase activity|upregulation of threonyl-transfer ribonucleic acid synthetase activity|upregulation of L-threonine:tRNAThr ligase (AMP-forming)|up-regulation of threonyl-tRNA synthetase activity|up-regulation of threonyl-transfer RNA synthetase activity|positive regulation of threonyl ribonucleic synthetase activity|up-regulation of threonine-transfer ribonucleate synthetase activity Any process that activates or increases the frequency, rate or extent of threonine-tRNA ligase activity. GO:1905024 regulation of membrane repolarization during ventricular cardiac muscle cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905024 regulation of electrocardiogram T wave|regulation of regulation of ventricular cardiac muscle repolarization|regulation of ventricular repolarization Any process that modulates the frequency, rate or extent of membrane repolarization during ventricular cardiac muscle cell action potential. GO:1905025 negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905025 inhibition of regulation of ventricular cardiac muscle repolarization|inhibition of ventricular repolarization|down regulation of membrane repolarization during ventricular cardiac muscle cell action potential|downregulation of electrocardiogram T wave|down regulation of regulation of ventricular cardiac muscle repolarization|downregulation of membrane repolarization during ventricular cardiac muscle cell action potential|down regulation of electrocardiogram T wave|downregulation of regulation of ventricular cardiac muscle repolarization|down-regulation of ventricular repolarization|negative regulation of ventricular repolarization|inhibition of electrocardiogram T wave|down-regulation of membrane repolarization during ventricular cardiac muscle cell action potential|down-regulation of regulation of ventricular cardiac muscle repolarization|negative regulation of regulation of ventricular cardiac muscle repolarization|downregulation of ventricular repolarization|inhibition of membrane repolarization during ventricular cardiac muscle cell action potential|down regulation of ventricular repolarization|down-regulation of electrocardiogram T wave|negative regulation of electrocardiogram T wave Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during ventricular cardiac muscle cell action potential. GO:1905015 regulation of isoleucine-tRNA ligase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905015 regulation of L-isoleucine:tRNAIle ligase (AMP-forming)|regulation of isoleucine-tRNA synthetase activity|regulation of isoleucyl-transfer ribonucleate synthetase activity|regulation of isoleucine-transfer RNA ligase activity|regulation of isoleucyl-tRNA synthetase activity|regulation of isoleucine translase activity|regulation of isoleucyl-transfer RNA synthetase activity Any process that modulates the frequency, rate or extent of isoleucine-tRNA ligase activity. GO:0090459 aspartate homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090459 Any process involved in the maintenance of an internal steady state of aspartate within an organism or cell. GO:1905016 negative regulation of isoleucine-tRNA ligase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905016 down regulation of isoleucyl-transfer RNA synthetase activity|inhibition of isoleucyl-tRNA synthetase activity|inhibition of L-isoleucine:tRNAIle ligase (AMP-forming)|inhibition of isoleucyl-transfer RNA synthetase activity|negative regulation of isoleucine-tRNA synthetase activity|down-regulation of isoleucine-tRNA synthetase activity|down-regulation of isoleucine-tRNA ligase activity|negative regulation of isoleucine-transfer RNA ligase activity|down-regulation of isoleucyl-transfer ribonucleate synthetase activity|negative regulation of isoleucyl-transfer ribonucleate synthetase activity|down-regulation of isoleucine-transfer RNA ligase activity|down-regulation of isoleucine translase activity|negative regulation of isoleucine translase activity|inhibition of isoleucine-tRNA synthetase activity|inhibition of isoleucine-tRNA ligase activity|inhibition of isoleucyl-transfer ribonucleate synthetase activity|inhibition of isoleucine-transfer RNA ligase activity|down regulation of L-isoleucine:tRNAIle ligase (AMP-forming)|inhibition of isoleucine translase activity|down-regulation of isoleucyl-tRNA synthetase activity|downregulation of L-isoleucine:tRNAIle ligase (AMP-forming)|negative regulation of isoleucyl-tRNA synthetase activity|down-regulation of isoleucyl-transfer RNA synthetase activity|negative regulation of isoleucyl-transfer RNA synthetase activity|down regulation of isoleucine-tRNA synthetase activity|down regulation of isoleucine-tRNA ligase activity|down regulation of isoleucyl-transfer ribonucleate synthetase activity|down regulation of isoleucine-transfer RNA ligase activity|downregulation of isoleucine-tRNA synthetase activity|down-regulation of L-isoleucine:tRNAIle ligase (AMP-forming)|negative regulation of L-isoleucine:tRNAIle ligase (AMP-forming)|downregulation of isoleucyl-tRNA synthetase activity|down regulation of isoleucine translase activity|downregulation of isoleucine-tRNA ligase activity|downregulation of isoleucine-transfer RNA ligase activity|downregulation of isoleucyl-transfer ribonucleate synthetase activity|downregulation of isoleucyl-transfer RNA synthetase activity|downregulation of isoleucine translase activity|down regulation of isoleucyl-tRNA synthetase activity Any process that stops, prevents or reduces the frequency, rate or extent of isoleucine-tRNA ligase activity. GO:1905017 positive regulation of isoleucine-tRNA ligase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905017 positive regulation of isoleucine-tRNA synthetase activity|up regulation of isoleucine-transfer RNA ligase activity|activation of isoleucine-tRNA ligase activity|up regulation of isoleucyl-transfer ribonucleate synthetase activity|activation of isoleucyl-transfer ribonucleate synthetase activity|activation of isoleucine-transfer RNA ligase activity|positive regulation of isoleucine-transfer RNA ligase activity|positive regulation of isoleucyl-transfer ribonucleate synthetase activity|up-regulation of L-isoleucine:tRNAIle ligase (AMP-forming)|up regulation of isoleucine translase activity|upregulation of isoleucyl-tRNA synthetase activity|activation of isoleucine translase activity|upregulation of isoleucyl-transfer RNA synthetase activity|positive regulation of isoleucine translase activity|up-regulation of isoleucine-tRNA synthetase activity|up-regulation of isoleucyl-tRNA synthetase activity|activation of isoleucyl-tRNA synthetase activity|upregulation of L-isoleucine:tRNAIle ligase (AMP-forming)|up-regulation of isoleucine-tRNA ligase activity|up-regulation of isoleucyl-transfer ribonucleate synthetase activity|up-regulation of isoleucyl-transfer RNA synthetase activity|up-regulation of isoleucine-transfer RNA ligase activity|activation of isoleucyl-transfer RNA synthetase activity|up-regulation of isoleucine translase activity|upregulation of isoleucine-tRNA synthetase activity|upregulation of isoleucine-tRNA ligase activity|up regulation of L-isoleucine:tRNAIle ligase (AMP-forming)|upregulation of isoleucine-transfer RNA ligase activity|upregulation of isoleucyl-transfer ribonucleate synthetase activity|positive regulation of isoleucyl-tRNA synthetase activity|activation of L-isoleucine:tRNAIle ligase (AMP-forming)|positive regulation of isoleucyl-transfer RNA synthetase activity|positive regulation of L-isoleucine:tRNAIle ligase (AMP-forming)|up regulation of isoleucyl-tRNA synthetase activity|upregulation of isoleucine translase activity|up regulation of isoleucyl-transfer RNA synthetase activity|up regulation of isoleucine-tRNA synthetase activity|up regulation of isoleucine-tRNA ligase activity|activation of isoleucine-tRNA synthetase activity Any process that activates or increases the frequency, rate or extent of isoleucine-tRNA ligase activity. GO:0090457 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090457 GO:0090458 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090458 GO:1905018 regulation of methionine-tRNA ligase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905018 regulation of methionyl-transfer ribonucleate synthetase activity|regulation of methionyl-tRNA synthetase activity|regulation of methionine translase activity|regulation of methionyl-transfer RNA synthetase activity|regulation of MetRS activity|regulation of methionyl-transfer ribonucleic acid synthetase activity|regulation of L-methionine:tRNAMet ligase (AMP-forming) Any process that modulates the frequency, rate or extent of methionine-tRNA ligase activity. GO:1905019 negative regulation of methionine-tRNA ligase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905019 inhibition of methionine translase activity|negative regulation of methionyl-tRNA synthetase activity|down-regulation of methionyl-tRNA synthetase activity|down-regulation of methionyl-transfer RNA synthetase activity|negative regulation of methionyl-transfer RNA synthetase activity|negative regulation of methionyl-transfer ribonucleic acid synthetase activity|down-regulation of methionyl-transfer ribonucleic acid synthetase activity|negative regulation of L-methionine:tRNAMet ligase (AMP-forming)|down-regulation of L-methionine:tRNAMet ligase (AMP-forming)|negative regulation of MetRS activity|down-regulation of MetRS activity|down regulation of methionine-tRNA ligase activity|down regulation of methionyl-transfer ribonucleate synthetase activity|inhibition of methionyl-transfer ribonucleic acid synthetase activity|downregulation of methionine-tRNA ligase activity|down regulation of methionine translase activity|downregulation of methionyl-tRNA synthetase activity|inhibition of L-methionine:tRNAMet ligase (AMP-forming)|downregulation of methionyl-transfer ribonucleate synthetase activity|downregulation of methionyl-transfer RNA synthetase activity|downregulation of MetRS activity|downregulation of methionine translase activity|down regulation of methionyl-tRNA synthetase activity|inhibition of methionyl-tRNA synthetase activity|down regulation of methionyl-transfer RNA synthetase activity|inhibition of methionyl-transfer RNA synthetase activity|down regulation of MetRS activity|inhibition of MetRS activity|down-regulation of methionine-tRNA ligase activity|down-regulation of methionyl-transfer ribonucleate synthetase activity|negative regulation of methionyl-transfer ribonucleate synthetase activity|down regulation of methionyl-transfer ribonucleic acid synthetase activity|down regulation of L-methionine:tRNAMet ligase (AMP-forming)|down-regulation of methionine translase activity|negative regulation of methionine translase activity|inhibition of methionine-tRNA ligase activity|inhibition of methionyl-transfer ribonucleate synthetase activity|downregulation of methionyl-transfer ribonucleic acid synthetase activity|downregulation of L-methionine:tRNAMet ligase (AMP-forming) Any process that stops, prevents or reduces the frequency, rate or extent of methionine-tRNA ligase activity. GO:0090451 cotyledon boundary formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090451 The process in which boundaries between a cotyledon and the surrounding tissue are established and maintained. GO:0090452 lithium ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090452 lithium ion import|lithium ion uptake The directed movement of lithium ions across a membrane. GO:0090450 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090450 GO:0090455 ornithine transmembrane import into vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090455 vacuolar ornithine import The directed movement of ornithine into the vacuole across the vacuolar membrane. GO:0090456 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090456 GO:0090453 aspartate transmembrane import into vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090453 vacuolar aspartate import The directed movement of aspartate into the vacuole across the vacuolar membrane. GO:0090454 glutamate transmembrane import into vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090454 vacuolar glutamate import The directed movement of glutamate into the vacuole across the vacuolar membrane. IAO:0000409 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/IAO_0000409 NCBITaxon:314146 Euarchontoglires organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_314146 GO:1905030 voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_1905030 voltage-dependent ion channel activity involved in regulation of post-synaptic membrane potential|voltage-gated ion channel activity involved in regulation of post-synaptic membrane potential|voltage-dependent ion channel activity involved in regulation of postsynaptic membrane potential|voltage gated ion channel activity involved in regulation of post-synaptic membrane potential|voltage gated ion channel activity involved in regulation of postsynaptic membrane potential Any voltage-gated ion channel activity that is involved in regulation of postsynaptic membrane potential. GO:1905031 regulation of membrane repolarization during cardiac muscle cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905031 Any process that modulates the frequency, rate or extent of membrane repolarization during cardiac muscle cell action potential. GO:1905032 negative regulation of membrane repolarization during cardiac muscle cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905032 down-regulation of membrane repolarization during cardiac muscle cell action potential|inhibition of membrane repolarization during cardiac muscle cell action potential|down regulation of membrane repolarization during cardiac muscle cell action potential|downregulation of membrane repolarization during cardiac muscle cell action potential Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during cardiac muscle cell action potential. GO:1905033 positive regulation of membrane repolarization during cardiac muscle cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905033 up-regulation of membrane repolarization during cardiac muscle cell action potential|upregulation of membrane repolarization during cardiac muscle cell action potential|up regulation of membrane repolarization during cardiac muscle cell action potential|activation of membrane repolarization during cardiac muscle cell action potential Any process that activates or increases the frequency, rate or extent of membrane repolarization during cardiac muscle cell action potential. GO:1905034 regulation of antifungal innate immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905034 Any process that modulates the frequency, rate or extent of an antifungal innate immune response. GO:1905035 negative regulation of antifungal innate immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905035 inhibition of antifungal innate immune response|down regulation of antifungal innate immune response|downregulation of antifungal innate immune response|down-regulation of antifungal innate immune response Any process that stops, prevents or reduces the frequency, rate or extent of an antifungal innate immune response. GO:1905036 positive regulation of antifungal innate immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905036 up-regulation of antifungal innate immune response|upregulation of antifungal innate immune response|up regulation of antifungal innate immune response|activation of antifungal innate immune response Any process that activates or increases the frequency, rate or extent of an antifungal innate immune response. GO:1905026 positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905026 upregulation of ventricular repolarization|positive regulation of electrocardiogram T wave|upregulation of membrane repolarization during ventricular cardiac muscle cell action potential|up regulation of electrocardiogram T wave|upregulation of regulation of ventricular cardiac muscle repolarization|up-regulation of ventricular repolarization|up regulation of membrane repolarization during ventricular cardiac muscle cell action potential|upregulation of electrocardiogram T wave|activation of membrane repolarization during ventricular cardiac muscle cell action potential|activation of ventricular repolarization|up regulation of regulation of ventricular cardiac muscle repolarization|positive regulation of regulation of ventricular cardiac muscle repolarization|positive regulation of ventricular repolarization|up regulation of ventricular repolarization|up-regulation of electrocardiogram T wave|activation of regulation of ventricular cardiac muscle repolarization|up-regulation of membrane repolarization during ventricular cardiac muscle cell action potential|activation of electrocardiogram T wave|up-regulation of regulation of ventricular cardiac muscle repolarization Any process that activates or increases the frequency, rate or extent of membrane repolarization during ventricular cardiac muscle cell action potential. GO:0090426 actin filament bundle convergence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090426 A process of actin filament bundle distribution that results in the compaction of actin filaments. GO:0090427 activation of meiosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090427 Any process that starts the inactive process of meiosis. GO:1905027 regulation of membrane depolarization during AV node cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905027 regulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential|regulation of membrane depolarization during AV node cardiac muscle cell action potential Any process that modulates the frequency, rate or extent of membrane depolarization during AV node cell action potential. GO:0090424 phytochelatin-metal-sulfur complex formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090424 high molecular weight phytochelatin complex formation|HWM phytochelatin complex formation A phytochelatin metabolic process in which a metal and exogenous sulfur are incorporated with phytochelatin to form a complex. GO:1905028 negative regulation of membrane depolarization during AV node cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905028 down regulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential|downregulation of membrane depolarization during AV node cell action potential|downregulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential|down regulation of membrane depolarization during AV node cardiac muscle cell action potential|down regulation of membrane depolarization during AV node cell action potential|inhibition of membrane depolarization during AV node cell action potential|downregulation of membrane depolarization during AV node cardiac muscle cell action potential|negative regulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential|down-regulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential|down-regulation of membrane depolarization during AV node cardiac muscle cell action potential|negative regulation of membrane depolarization during AV node cardiac muscle cell action potential|inhibition of membrane depolarization during atrioventricular node cardiac muscle cell action potential|down-regulation of membrane depolarization during AV node cell action potential|inhibition of membrane depolarization during AV node cardiac muscle cell action potential Any process that stops, prevents or reduces the frequency, rate or extent of membrane depolarization during AV node cell action potential. GO:1905029 positive regulation of membrane depolarization during AV node cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905029 upregulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential|up regulation of membrane depolarization during AV node cell action potential|upregulation of membrane depolarization during AV node cardiac muscle cell action potential|up regulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential|upregulation of membrane depolarization during AV node cell action potential|activation of membrane depolarization during atrioventricular node cardiac muscle cell action potential|positive regulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential|up regulation of membrane depolarization during AV node cardiac muscle cell action potential|activation of membrane depolarization during AV node cardiac muscle cell action potential|positive regulation of membrane depolarization during AV node cardiac muscle cell action potential|up-regulation of membrane depolarization during AV node cell action potential|activation of membrane depolarization during AV node cell action potential|up-regulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential|up-regulation of membrane depolarization during AV node cardiac muscle cell action potential Any process that activates or increases the frequency, rate or extent of membrane depolarization during AV node cell action potential. GO:0090425 acinar cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090425 The epithelial cell differentiation process in which a relatively unspecialized cell acquires specialized features of an acinar cell, a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini. GO:0090428 perianth development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090428 The process whose specific outcome is the progression of the perianth over time, from its formation to the mature structure. The perianth is a collective phyllome structure composed of two or more petals, sepals, or tepals. GO:0090429 detection of endogenous biotic stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090429 The series of events in which an endogenous biotic stimulus is received by a cell and converted into a molecular signal. GO:0090422 thiamine pyrophosphate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090422 Reactome:R-HSA-8875838 thiamine pyrophosphate transporter activity|thiamine diphosphate transporter activity Enables the transfer of thiamine pyrophosphate a substance from one side of a membrane to the other. GO:0090423 phytochelatin-metal complex formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090423 LWM phytochelatin complex formation|low molecular weight phytochelatin complex formation A phytochelatin metabolic process in which a metal is incorporated with phytochelatin to form a complex. IAO:0000410 universal biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/IAO_0000410 GO:0090420 naphthalene-containing compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090420 The chemical reactions and pathways involving naphthalene-containing compounds. GO:0090421 embryonic meristem initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090421 Initiation of a region of tissue in a plant embryo that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation. GO:1905040 otic placode development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905040 ear placode development|octaval VIII placode development|placoda otica development|octaval placode development|auditory placode development|ear/otic placode development The process whose specific outcome is the progression of an otic placode over time, from its formation to the mature structure. GO:1905041 regulation of epithelium regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905041 regulation of regeneration of epithelium Any process that modulates the frequency, rate or extent of epithelium regeneration. GO:1905042 negative regulation of epithelium regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905042 inhibition of epithelium regeneration|down-regulation of regeneration of epithelium|negative regulation of regeneration of epithelium|down regulation of epithelium regeneration|downregulation of regeneration of epithelium|downregulation of epithelium regeneration|down regulation of regeneration of epithelium|inhibition of regeneration of epithelium|down-regulation of epithelium regeneration Any process that stops, prevents or reduces the frequency, rate or extent of epithelium regeneration. GO:1905043 positive regulation of epithelium regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905043 up-regulation of epithelium regeneration|positive regulation of regeneration of epithelium|upregulation of epithelium regeneration|up regulation of regeneration of epithelium|up regulation of epithelium regeneration|upregulation of regeneration of epithelium|activation of epithelium regeneration|up-regulation of regeneration of epithelium|activation of regeneration of epithelium Any process that activates or increases the frequency, rate or extent of epithelium regeneration. GO:1905044 regulation of Schwann cell proliferation involved in axon regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905044 Any process that modulates the frequency, rate or extent of Schwann cell proliferation involved in axon regeneration. GO:1905045 negative regulation of Schwann cell proliferation involved in axon regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905045 down-regulation of Schwann cell proliferation involved in axon regeneration|downregulation of Schwann cell proliferation involved in axon regeneration|down regulation of Schwann cell proliferation involved in axon regeneration|inhibition of Schwann cell proliferation involved in axon regeneration Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell proliferation involved in axon regeneration. GO:1905046 positive regulation of Schwann cell proliferation involved in axon regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905046 up regulation of Schwann cell proliferation involved in axon regeneration|upregulation of Schwann cell proliferation involved in axon regeneration|up-regulation of Schwann cell proliferation involved in axon regeneration|activation of Schwann cell proliferation involved in axon regeneration Any process that activates or increases the frequency, rate or extent of Schwann cell proliferation involved in axon regeneration. GO:1905047 mitotic spindle pole body organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905047 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitotic spindle pole body. GO:0090437 socket cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090437 The process in which a relatively unspecialized cell acquires specialized features of a socket cell, a shoot epidermal cell that surrounds a trichome and provides its support. GO:1905037 autophagosome organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905037 autophagic vacuole organization|initial autophagic vacuole organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an autophagosome. GO:0090438 camelliol C synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090438 (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, camelliol-C-forming) Catalyzes the reaction: (3S)-2,3-epoxy-2,3-dihydrosqualene = camelliol C. GO:1905038 regulation of membrane lipid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905038 regulation of membrane lipid metabolism Any process that modulates the frequency, rate or extent of membrane lipid metabolic process. GO:0090435 protein localization to nuclear envelope biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090435 protein localization in nuclear envelope A process in which a protein is transported to, or maintained at, a location within a nuclear envelope. GO:1905039 carboxylic acid transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905039 The process in which carboxylic acid is transported across a membrane. GO:0090436 leaf pavement cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090436 The process whose specific outcome is the progression of an leaf pavement cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a leaf pavement cell fate. GO:0090439 tetraketide alpha-pyrone synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090439 Catalyzes the reaction: a hydroxyacyl-CoA + 3 malonyl-CoA + 2 H+ = a hydroxylated tetraketide alpha-pyrone + 3 CO2 + 4 coenzyme A . GO:0090430 caffeoyl-CoA: alcohol caffeoyl transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090430 Catalysis of the reaction: caffeoyl-CoA + a saturated primary alcohol = an alkyl caffeate + CoA. IAO:0000423 to be replaced with external ontology term biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/IAO_0000423 Terms with this status should eventually replaced with a term from another ontology. IAO:0000420 defined class biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/IAO_0000420 A defined class is a class that is defined by a set of logically necessary and sufficient conditions but is not a universal GO:0090433 palmitoyl-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090433 Reactome:R-HSA-434382 palmitoyl-CoA synthetase activity Catalysis of the reaction: ATP + palmitic acid + CoA = AMP + diphosphate + palmitoyl-CoA. IAO:0000421 named class expression biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/IAO_0000421 A named class expression is a logical expression that is given a name. The name can be used in place of the expression. GO:0090434 oleoyl-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090434 oleoyl-CoA synthetase activity Catalysis of the reaction: ATP + oleic acid + CoA = AMP + diphosphate + oleoyl-CoA. GO:0090431 alkyl caffeate ester biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090431 alkyl caffeate ester anabolism|alkyl caffeate ester biosynthesis|alkyl caffeate ester synthesis|alkyl caffeate ester formation The chemical reactions and pathways resulting in the formation of ester derivatives of alkyl caffeate. GO:0090432 myristoyl-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090432 myristoyl-CoA synthetase activity Catalysis of the reaction: ATP + myristic acid + CoA = AMP + diphosphate + myristoyl-CoA. GO:0090480 purine nucleotide-sugar transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090480 purine nucleotide-sugar transport|purine nucleotide-sugar membrane transport The process in which a purine nucleotide-sugar is transported across a membrane. Purine nucleotide-sugars are purine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative. GO:0090481 pyrimidine nucleotide-sugar transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090481 pyrimidine nucleotide-sugar transport|pyrimidine nucleotide-sugar membrane transport The process in which a pyrimidine nucleotide-sugar is transported across a membrane. Pyrimidine nucleotide-sugars are pyrimidine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative. GO:1905050 positive regulation of metallopeptidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905050 upregulation of metallopeptidase activity|upregulation of metalloproteinase activity|upregulation of metalloprotease activity|up regulation of metallopeptidase activity|activation of metallopeptidase activity|up-regulation of metalloproteinase activity|up-regulation of metalloprotease activity|activation of metalloproteinase activity|positive regulation of metalloproteinase activity|activation of metalloprotease activity|up-regulation of metallopeptidase activity|up regulation of metalloproteinase activity|positive regulation of metalloprotease activity|up regulation of metalloprotease activity Any process that activates or increases the frequency, rate or extent of metallopeptidase activity. GO:1905051 regulation of base-excision repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905051 regulation of BER Any process that modulates the frequency, rate or extent of base-excision repair. GO:1905052 negative regulation of base-excision repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905052 inhibition of BER|down-regulation of base-excision repair|down regulation of BER|downregulation of BER|downregulation of base-excision repair|down regulation of base-excision repair|inhibition of base-excision repair|negative regulation of BER|down-regulation of BER Any process that stops, prevents or reduces the frequency, rate or extent of base-excision repair. GO:1905053 positive regulation of base-excision repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905053 up-regulation of BER|up-regulation of base-excision repair|activation of base-excision repair|upregulation of BER|up regulation of base-excision repair|up regulation of BER|activation of BER|positive regulation of BER|upregulation of base-excision repair Any process that activates or increases the frequency, rate or extent of base-excision repair. GO:1905054 calcium-induced calcium release activity involved in regulation of presynaptic cytosolic calcium ion concentration biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_1905054 calcium-induced calcium release activity involved in regulation of presynaptic cytosolic calcium levels Any calcium-induced calcium release activity that is involved in regulation of presynaptic cytosolic calcium ion concentration. GO:1905055 calcium:cation antiporter activity involved in regulation of presynaptic cytosolic calcium ion concentration biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_1905055 calcium ion antiporter activity involved in regulation of presynaptic cytosolic calcium levels Any calcium:cation antiporter activity that is involved in regulation of presynaptic cytosolic calcium ion concentration. GO:1905056 calcium-transporting ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_1905056 ATPase-coupled calcium ion transmembrane transporter activity involved in regulation of presynaptic cytosolic calcium levels|calcium ABC transporter involved in regulation of presynaptic cytosolic calcium ion concentration|Ca2+-transporting ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration|calcium transporting ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration|ATP phosphohydrolase (Ca2+-transporting) involved in regulation of presynaptic cytosolic calcium ion concentration|calcium-translocating P-type ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration|calcium efflux ATPase involved in regulation of presynaptic cytosolic calcium ion concentration|Ca2+-pumping ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration|plasma membrane Ca-ATPase involved in regulation of presynaptic cytosolic calcium ion concentration|Ca(2+)-transporting ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration Any calcium-transporting ATPase activity that is involved in regulation of presynaptic cytosolic calcium ion concentration. GO:1905057 voltage-gated calcium channel activity involved in regulation of postsynaptic cytosolic calcium levels biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_1905057 depolarization-activated voltage gated calcium channel activity involved in regulation of postsynaptic cytosolic calcium ion concentration|depolarization-activated voltage-gated calcium channel involved in regulation of postsynaptic cytosolic calcium ion concentration|voltage gated calcium channel activity involved in regulation of postsynaptic cytosolic calcium ion concentration|depolarization-activated voltage-gated calcium channel activity involved in regulation of postsynaptic cytosolic calcium ion concentration|dihydropyridine-sensitive calcium channel activity involved in regulation of postsynaptic cytosolic calcium ion concentration|voltage-gated calcium ion channel activity involved in regulation of postsynaptic cytosolic calcium ion concentration|voltage-gated calcium channel activity involved in regulation of postsynaptic cytosolic calcium levels|voltage-dependent calcium channel activity involved in regulation of postsynaptic cytosolic calcium ion concentration|voltage-sensitive calcium channel involved in regulation of postsynaptic cytosolic calcium ion concentration Any voltage-gated calcium channel activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration. GO:1905058 calcium-induced calcium release activity involved in regulation of postsynaptic cytosolic calcium ion concentration biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_1905058 calcium-induced calcium release activity involved in regulation of postsynaptic cytosolic calcium levels Any calcium-induced calcium release activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration. GO:1905048 regulation of metallopeptidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905048 regulation of metalloproteinase activity|regulation of metalloprotease activity Any process that modulates the frequency, rate or extent of metallopeptidase activity. GO:1905049 negative regulation of metallopeptidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905049 inhibition of metalloprotease activity|down-regulation of metallopeptidase activity|negative regulation of metalloproteinase activity|down-regulation of metalloproteinase activity|inhibition of metallopeptidase activity|negative regulation of metalloprotease activity|down-regulation of metalloprotease activity|downregulation of metalloproteinase activity|down regulation of metalloproteinase activity|downregulation of metalloprotease activity|down regulation of metallopeptidase activity|down regulation of metalloprotease activity|inhibition of metalloproteinase activity|downregulation of metallopeptidase activity Any process that stops, prevents or reduces the frequency, rate or extent of metallopeptidase activity. GO:0090484 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090484 GO:0090485 obsolete chromosome number maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090485 haploidization|diploidization OBSOLETE. The maintenance of the standard number of chromosomes in a cell. GO:0090482 vitamin transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090482 vitamin or cofactor transporter activity|vitamin transporter activity Enables the transfer of a vitamin from one side of a membrane to the other. GO:0090483 phosphatidylglycerol-phosphatidylethanolamine phosphatidyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090483 cardiolipin synthase Catalysis of the reaction: phosphatidylglycerol + phosphatidylethanolamine = cardiolipin + ethanolamine. GO:0090488 polo box domain specific binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090488 Interacting selectively and non-covalently with a polo box domain of a protein. The polo box domain is involved in binding substrates of polo kinases. GO:0090489 L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating, decarboxylating) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090489 tryptophan N-monooxygenase activity Catalyzes the multi-step reaction: L-Tryptophan + 2 Oxygen + 2 NADPH + 2 H+ = Indole-3-acetaldehyde oxime + 3 H2O + 2 NADP+ + CO2. The individual reactions are: (1a) L-tryptophan + O2 + NADPH + H+ = N-hydroxy-L-tryptophan + NADP+ + H2O,(1b) N-hydroxy-L-tryptophan + O2 + NADPH + H+ = N,N-dihydroxy-L-tryptophan + NADP+ + H2O, and (1c) N,N-dihydroxy-L-tryptophan = (E)-indol-3-ylacetaldoxime + CO2 + H2O. GO:0090486 small RNA 2'-O-methyltransferase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090486 Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a nucleoside residue in a small RNA molecule. Reaction: S-adenosyl-L-methionine + small RNA <=> S-adenosyl-L-homocysteine + small RNA containing a 3'-terminal 2'-O-methylnucleotide. GO:0090487 secondary metabolite catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090487 secondary metabolite degradation|secondary metabolite breakdown|secondary metabolite catabolism The chemical reactions and pathways resulting in the breakdown of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. GO:0090491 N-hydroxy-L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090491 Catalyzes the reaction: N-Hydroxy-L-tryptophan + Oxygen + NADPH + H+ = N,N-Dihydroxy-L-tryptophan + NADP+ + H2O. GO:0090492 N,N-Dihydroxy-L-tryptophan decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090492 Catalyzes the reaction: N,N-Dihydroxy-L-tryptophan = Indole-3-acetaldehyde oxime + CO2 + H2O. GO:1905060 calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_1905060 calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion levels Any calcium:cation antiporter activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration. GO:1905061 negative regulation of cardioblast proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905061 downregulation of cardioblast proliferation|down-regulation of cardioblast proliferation|inhibition of cardioblast proliferation|down regulation of cardioblast proliferation Any process that stops, prevents or reduces the frequency, rate or extent of cardioblast proliferation. GO:0090490 L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090490 Catalyzes the reaction: L-Tryptophan + Oxygen + NADPH + H+ = N-Hydroxy-L-tryptophan + NADP+ + H2O. GO:1905062 positive regulation of cardioblast proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905062 up regulation of cardioblast proliferation|activation of cardioblast proliferation|up-regulation of cardioblast proliferation|upregulation of cardioblast proliferation Any process that activates or increases the frequency, rate or extent of cardioblast proliferation. GO:1905063 regulation of vascular associated smooth muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905063 regulation of vascular smooth muscle cell differentiation|regulation of VSMC differentiation Any process that modulates the frequency, rate or extent of vascular smooth muscle cell differentiation. GO:1905064 negative regulation of vascular associated smooth muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905064 down-regulation of VSMC differentiation|negative regulation of VSMC differentiation|downregulation of vascular associated smooth muscle cell differentiation|down regulation of vascular associated smooth muscle cell differentiation|inhibition of vascular associated smooth muscle cell differentiation|down regulation of vascular smooth muscle cell differentiation|downregulation of VSMC differentiation|downregulation of vascular smooth muscle cell differentiation|down regulation of VSMC differentiation|inhibition of VSMC differentiation|negative regulation of vascular smooth muscle cell differentiation|down-regulation of vascular smooth muscle cell differentiation|down-regulation of vascular associated smooth muscle cell differentiation|inhibition of vascular smooth muscle cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell differentiation. GO:1905065 positive regulation of vascular associated smooth muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905065 activation of VSMC differentiation|up-regulation of vascular smooth muscle cell differentiation|up regulation of vascular associated smooth muscle cell differentiation|upregulation of vascular smooth muscle cell differentiation|positive regulation of VSMC differentiation|up regulation of VSMC differentiation|upregulation of vascular associated smooth muscle cell differentiation|up regulation of vascular smooth muscle cell differentiation|positive regulation of vascular smooth muscle cell differentiation|activation of vascular smooth muscle cell differentiation|upregulation of VSMC differentiation|up-regulation of vascular associated smooth muscle cell differentiation|activation of vascular associated smooth muscle cell differentiation|up-regulation of VSMC differentiation Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell differentiation. GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905066 regulation of canonical Wnt receptor signalling pathway involved in heart development|regulation of canonical Wnt-activated signaling pathway involved in heart development|regulation of canonical Wnt receptor signaling pathway involved in heart development Any process that modulates the frequency, rate or extent of canonical Wnt signaling pathway involved in heart development. GO:1905067 negative regulation of canonical Wnt signaling pathway involved in heart development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905067 inhibition of canonical Wnt receptor signaling pathway involved in heart development|negative regulation of canonical Wnt-activated signaling pathway involved in heart development|down-regulation of canonical Wnt-activated signaling pathway involved in heart development|inhibition of canonical Wnt receptor signalling pathway involved in heart development|down-regulation of canonical Wnt signaling pathway involved in heart development|inhibition of canonical Wnt-activated signaling pathway involved in heart development|inhibition of canonical Wnt signaling pathway involved in heart development|down-regulation of canonical Wnt receptor signaling pathway involved in heart development|negative regulation of canonical Wnt receptor signaling pathway involved in heart development|down regulation of canonical Wnt receptor signalling pathway involved in heart development|downregulation of canonical Wnt receptor signalling pathway involved in heart development|down regulation of canonical Wnt-activated signaling pathway involved in heart development|downregulation of canonical Wnt receptor signaling pathway involved in heart development|down regulation of canonical Wnt signaling pathway involved in heart development|downregulation of canonical Wnt-activated signaling pathway involved in heart development|down regulation of canonical Wnt receptor signaling pathway involved in heart development|downregulation of canonical Wnt signaling pathway involved in heart development|down-regulation of canonical Wnt receptor signalling pathway involved in heart development|negative regulation of canonical Wnt receptor signalling pathway involved in heart development Any process that stops, prevents or reduces the frequency, rate or extent of canonical Wnt signaling pathway involved in heart development. GO:1905068 positive regulation of canonical Wnt signaling pathway involved in heart development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905068 positive regulation of canonical Wnt-activated signaling pathway involved in heart development|up regulation of canonical Wnt signaling pathway involved in heart development|upregulation of canonical Wnt receptor signaling pathway involved in heart development|activation of canonical Wnt signaling pathway involved in heart development|up-regulation of canonical Wnt receptor signalling pathway involved in heart development|activation of canonical Wnt receptor signaling pathway involved in heart development|up-regulation of canonical Wnt-activated signaling pathway involved in heart development|up-regulation of canonical Wnt receptor signaling pathway involved in heart development|up-regulation of canonical Wnt signaling pathway involved in heart development|upregulation of canonical Wnt receptor signalling pathway involved in heart development|upregulation of canonical Wnt-activated signaling pathway involved in heart development|positive regulation of canonical Wnt receptor signaling pathway involved in heart development|up regulation of canonical Wnt receptor signaling pathway involved in heart development|upregulation of canonical Wnt signaling pathway involved in heart development|up regulation of canonical Wnt receptor signalling pathway involved in heart development|activation of canonical Wnt receptor signalling pathway involved in heart development|positive regulation of canonical Wnt receptor signalling pathway involved in heart development|up regulation of canonical Wnt-activated signaling pathway involved in heart development|activation of canonical Wnt-activated signaling pathway involved in heart development Any process that activates or increases the frequency, rate or extent of canonical Wnt signaling pathway involved in heart development. GO:1905069 allantois development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905069 allantoic bud development The process whose specific outcome is the progression of an allantois over time, from its formation to the mature structure. GO:1905059 calcium-transporting ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_1905059 Ca(2+)-transporting ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration|Ca2+-pumping ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration|sarcoplasmic reticulum ATPase involved in regulation of postsynaptic cytosolic calcium ion concentration|calcium ABC transporter involved in regulation of postsynaptic cytosolic calcium ion concentration|ATP phosphohydrolase (Ca2+-transporting) involved in regulation of postsynaptic cytosolic calcium ion concentration|calcium transporting ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration|Ca2+-transporting ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration|ATPase-coupled calcium ion transmembrane transporter activity involved in regulation of postsynaptic cytosolic calcium levels|sarco(endo)plasmic reticulum Ca2+-ATPase involved in regulation of postsynaptic cytosolic calcium ion concentration|plasma membrane Ca-ATPase involved in regulation of postsynaptic cytosolic calcium ion concentration|calcium-transporting ATPase activity involved in regulation of postsynaptic cytosolic calcium levels|calcium efflux ATPase involved in regulation of postsynaptic cytosolic calcium ion concentration|calcium-translocating P-type ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration Any calcium-transporting ATPase activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration. GO:0090495 low-density lipoprotein particle disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090495 The disaggregation of a low-density lipoprotein particle into its constituent components. GO:0090496 mesenchyme migration involved in limb bud formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090496 The migration of mesenchymal tissue that contributes to the formation of a limb bud. GO:0090493 catecholamine uptake biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090493 The directed movement of catecholamine into a cell. GO:0090494 dopamine uptake biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090494 The directed movement of dopamine into a cell. GO:0090499 pimelyl-[acyl-carrier protein] methyl ester esterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090499 pimelyl-[acyl-carrier protein] methyl ester hydrolase activity Catalysis of the reaction: pimelyl-[acyl-carrier protein] methyl ester + H2O = pimelyl-[acyl-carrier protein] + methanol. GO:0090497 mesenchymal cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090497 The orderly movement of a mesenchymal cell from one site to another, often during the development of a multicellular organism. CHEBI:5254 galactolipid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_5254 GO:0090498 extrinsic component of Golgi membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090498 extrinsic to Golgi membrane The component of a Golgi membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:0016490 structural constituent of peritrophic membrane biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016490 structural constituent of peritrophic matrix The action of a molecule that contributes to the structural integrity of the peritrophic membrane, a tubular sheath of cuticle that shields the epithelial cells of the midgut from the gut contents. An example of this is found in Drosophila melanogaster. GO:1905070 anterior visceral endoderm cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905070 The orderly movement of an anterior visceral endoderm cell from one site to another. GO:1905071 tight junction disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905071 occluding junction disassembly|occluding cell junction disassembly The disaggregation of an tight junction into its constituent components. GO:1905072 cardiac jelly development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905072 heart cardiac jelly development The process whose specific outcome is the progression of cardiac jelly over time, from its formation to the mature structure. GO:1905073 regulation of tight junction disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905073 regulation of occluding cell junction disassembly|regulation of occluding junction disassembly Any process that modulates the frequency, rate or extent of tight junction disassembly. GO:1905074 negative regulation of tight junction disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905074 negative regulation of tight junction disassembly|down-regulation of tight junction disassembly|downregulation of occluding junction disassembly|downregulation of occluding cell junction disassembly|inhibition of occluding junction disassembly|downregulation of tight junction disassembly|down-regulation of occluding cell junction disassembly|negative regulation of occluding cell junction disassembly|down regulation of tight junction disassembly|inhibition of tight junction disassembly|inhibition of occluding cell junction disassembly|down regulation of occluding cell junction disassembly Any process that stops, prevents or reduces the frequency, rate or extent of tight junction disassembly. GO:1905075 positive regulation of tight junction disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905075 up regulation of occluding cell junction disassembly|positive regulation of occluding cell junction disassembly|activation of occluding cell junction disassembly|up regulation of tight junction disassembly|upregulation of tight junction disassembly|up-regulation of occluding cell junction disassembly|activation of occluding junction disassembly|up-regulation of tight junction disassembly|upregulation of occluding cell junction disassembly|activation of tight junction disassembly|positive regulation of occluding junction disassembly Any process that activates or increases the frequency, rate or extent of tight junction disassembly. GO:1905076 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1905076 GO:1905077 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1905077 GO:1905078 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1905078 GO:1905079 regulation of cerebellar neuron development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905079 Any process that modulates the frequency, rate or extent of cerebellar neuron development. GO:0090468 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090468 GO:0090469 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090469 GO:0016488 farnesol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016488 farnesol catabolism|farnesol degradation|farnesol breakdown The chemical reactions and pathways resulting in the breakdown of the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol. GO:0016489 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016489 GO:0090462 ornithine homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090462 Any process involved in the maintenance of an internal steady state of ornithine within an organism or cell. GO:0016484 obsolete proprotein convertase 2 activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016484 proprotein convertase 2 activator activity OBSOLETE. Required for the maturation and activation of proprotein convertase 2. GO:0090463 lysine homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090463 Any process involved in the maintenance of an internal steady state of lysine within an organism or cell. GO:0016485 protein processing biolink:BiologicalProcess go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0016485 protein maturation by peptide bond hydrolysis|protein maturation by peptide bond cleavage|peptidolysis during protein maturation|protein maturation by proteolysis Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein. GO:0016486 peptide hormone processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016486 The generation of a mature peptide hormone by posttranslational processing of a prohormone. GO:0090460 threonine homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090460 Any process involved in the maintenance of an internal steady state of threonine within an organism or cell. GO:0090461 glutamate homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090461 Any process involved in the maintenance of an internal steady state of glutamate within an organism or cell. GO:0016487 farnesol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016487 farnesol metabolism The chemical reactions and pathways involving the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol. GO:0016480 negative regulation of transcription by RNA polymerase III biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016480 inhibition of transcription from RNA polymerase III promoter|negative regulation of transcription from Pol III promoter|down-regulation of transcription from RNA polymerase III promoter|negative regulation of transcription from RNA polymerase III promoter|downregulation of transcription from RNA polymerase III promoter|down regulation of transcription from RNA polymerase III promoter Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase III. GO:0090466 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090466 GO:0016481 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016481 GO:0090467 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090467 GO:0090464 histidine homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090464 Any process involved in the maintenance of an internal steady state of histidine within an organism or cell. GO:0016482 cytosolic transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016482 The directed movement of substances or organelles within the cytosol. GO:0090465 arginine homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090465 Any process involved in the maintenance of an internal steady state of arginine within an organism or cell. GO:0016483 tryptophan hydroxylase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016483 Increases the activity of the enzyme tryptophase hydroxylase. GO:1905080 negative regulation of cerebellar neuron development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905080 down regulation of cerebellar neuron development|downregulation of cerebellar neuron development|down-regulation of cerebellar neuron development|inhibition of cerebellar neuron development Any process that stops, prevents or reduces the frequency, rate or extent of cerebellar neuron development. GO:1905081 positive regulation of cerebellar neuron development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905081 upregulation of cerebellar neuron development|up regulation of cerebellar neuron development|activation of cerebellar neuron development|up-regulation of cerebellar neuron development Any process that activates or increases the frequency, rate or extent of cerebellar neuron development. GO:0090470 shoot organ boundary specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090470 The process in which the basal boundary between the stem and both vegetative and reproductive organs are established and maintained. GO:1905082 regulation of mitochondrial translational elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905082 regulation of mitochondrial translation elongation Any process that modulates the frequency, rate or extent of mitochondrial translational elongation. GO:1905083 negative regulation of mitochondrial translational elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905083 down-regulation of mitochondrial translation elongation|negative regulation of mitochondrial translation elongation|downregulation of mitochondrial translation elongation|down-regulation of mitochondrial translational elongation|down regulation of mitochondrial translation elongation|inhibition of mitochondrial translation elongation|downregulation of mitochondrial translational elongation|down regulation of mitochondrial translational elongation|inhibition of mitochondrial translational elongation Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial translational elongation. GO:1905084 positive regulation of mitochondrial translational elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905084 positive regulation of mitochondrial translation elongation|up-regulation of mitochondrial translational elongation|activation of mitochondrial translational elongation|up regulation of mitochondrial translation elongation|upregulation of mitochondrial translation elongation|up regulation of mitochondrial translational elongation|up-regulation of mitochondrial translation elongation|activation of mitochondrial translation elongation|upregulation of mitochondrial translational elongation Any process that activates or increases the frequency, rate or extent of mitochondrial translational elongation. GO:1905085 regulation of bioluminescence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905085 Any process that modulates the frequency, rate or extent of bioluminescence. GO:1905086 negative regulation of bioluminescence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905086 down regulation of bioluminescence|downregulation of bioluminescence|down-regulation of bioluminescence|inhibition of bioluminescence Any process that stops, prevents or reduces the frequency, rate or extent of bioluminescence. GO:1905087 positive regulation of bioluminescence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905087 upregulation of bioluminescence|up regulation of bioluminescence|activation of bioluminescence|up-regulation of bioluminescence Any process that activates or increases the frequency, rate or extent of bioluminescence. GO:1905088 positive regulation of synaptonemal complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905088 upregulation of synaptonemal complex assembly|up-regulation of synaptonemal complex formation|activation of synaptonemal complex formation|up regulation of synaptonemal complex assembly|activation of synaptonemal complex assembly|positive regulation of synaptonemal complex formation|up regulation of synaptonemal complex formation|up-regulation of synaptonemal complex assembly|upregulation of synaptonemal complex formation Any process that activates or increases the frequency, rate or extent of synaptonemal complex assembly. GO:1905089 regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905089 regulation of PRKN-mediated stimulation of mitophagy in response to mitochondrial depolarization|regulation of Park2-mediated stimulation of mitophagy in response to mitochondrial depolarization Any process that modulates the frequency, rate or extent of a parkin-mediated process that positively regulates mitophagy in response to mitochondrial depolarization. GO:0090479 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090479 GO:0016499 orexin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016499 Combining with orexin to initiate a change in cell activity. GO:0016495 C-X3-C chemokine receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016495 Combining with a C-X3-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A C-X3-C chemokine has three amino acids between the first two cysteines of the characteristic four-cysteine motif. GO:0090473 lys-arg specific dibasic protein processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090473 Any protein processing achieved by the cleavage of a peptide bond after a lysine-arginine amino acid residue combination within a protein. GO:0090474 arg-arg specific dibasic protein processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090474 Any protein processing achieved by the cleavage of a peptide bond after two consecutive arginine amino acid residues within a protein. GO:0016496 substance P receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016496 Combining with substance P, the peptide Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met, to initiate a change in cell activity. GO:0090471 9,15,9'-tri-cis-zeta-carotene isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090471 9,15,9'-tricis-zeta-carotene cis-trans-isomerase Catalysis of the reaction: 9,15,9'-tricis-zeta-carotene = 9,9'-dicis-zeta-carotene. GO:0016497 substance K receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016497 neuromedin L receptor activity|neurokinin A receptor activity Combining with substance K, the peptide His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met, to initiate a change in cell activity. GO:0090472 dibasic protein processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090472 Any protein processing achieved by the cleavage of a peptide bond after two basic amino acids within a protein. GO:0016498 neuromedin K receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016498 neurokinin B receptor activity Combining with neuromedin K, the peptide Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met to initiate a change in cell activity. GO:0016491 oxidoreductase activity biolink:MolecularActivity go-plus goslim_generic|goslim_chembl|goslim_mouse|goslim_candida|goslim_yeast|goslim_pir|goslim_drosophila|goslim_aspergillus|goslim_metagenomics http://purl.obolibrary.org/obo/GO_0016491 Reactome:R-HSA-8936442|Reactome:R-HSA-8878581|Reactome:R-HSA-9024624|Reactome:R-HSA-9024630|EC:1.-.-.-|Reactome:R-HSA-9027033|Reactome:R-HSA-3095889|Reactome:R-HSA-9020249|Reactome:R-HSA-9020260|Reactome:R-HSA-5662660|Reactome:R-HSA-9026917|Reactome:R-HSA-1614362|Reactome:R-HSA-9693722|Reactome:R-HSA-9025007|RHEA:27453|Reactome:R-HSA-9026001|Reactome:R-HSA-209921|Reactome:R-HSA-390438|Reactome:R-HSA-390425|Reactome:R-HSA-209960 redox activity|oxidoreductase activity, acting on other substrates Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. GO:0090477 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090477 GO:0090478 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090478 GO:0016492 G protein-coupled neurotensin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016492 G protein coupled neurotensin receptor activity|neurotensin receptor activity, G-protein coupled|neurotensin receptor activity, G protein coupled|G-protein coupled neurotensin receptor activity Combining with the tridecapeptide neurotensin to initiate a G-protein mediated change in cell activity. A G-protein is a signal transduction molecule that alternates between an inactive GDP-bound and an active GTP-bound state. GO:0090475 lys-lys specific dibasic protein processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090475 Any protein processing achieved by the cleavage of a peptide bond after two consecutive lysine amino acid residues within a protein. GO:0016493 C-C chemokine receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016493 Combining with a C-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif. GO:0090476 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090476 GO:0016494 C-X-C chemokine receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016494 Combining with a C-X-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A C-X-C chemokine has a single amino acid between the first two cysteines of the characteristic four cysteine motif. CHEBI:90151 alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90151 CHEBI:65190 first generation antipsychotic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65190 UBERON:0018261 muscular coat of digestive tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018261 muscular layer of digestive tract|tunica externa of digestive tract|muscularis externa of digestive tract|tunica muscularis of digestive tract A muscular coat that is part of a digestive tract. CHEBI:65191 second generation antipsychotic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65191 PR:000003171 IGFBP-related protein biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000003171 PR:000003172 connective tissue growth factor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000003172 insulin-like growth factor-binding protein 8|HCS24|protein FISP-12|CTGF|Fisp-12|IBP-8|IGFBP-8|CCN2|IGFBP8|Fisp12|IGF-binding protein 8|hypertrophic chondrocyte-specific protein 24|CCN family member 2 An IGFBP-related protein that is a translation product of the human CTGF gene or a 1:1 ortholog thereof. CHEBI:16218 beta-D-glucose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16218 CHEBI:16219 cucurbitacin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16219 CHEBI:16216 3-(acetamidomethylidene)-2-(hydroxymethyl)succinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16216 CHEBI:16217 D-glucono-1,5-lactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16217 CHEBI:16214 dolichyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16214 CHEBI:16215 phosphonate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16215 CHEBI:90157 2-methylhexenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90157 UBERON:0018260 layer of muscle tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018260 Any organ component layer that consists of muscle tissue. CHEBI:90158 N-carbamoylaspartate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90158 CHEBI:16213 coformycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16213 CHEBI:90159 geranyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90159 CHEBI:16210 sinapoyltartronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16210 CHEBI:16211 cis-2-chloro-4-carboxymethylenebut-2-en-1,4-olide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16211 CHEBI:90153 alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer(d18:1/18:0)(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90153 CHEBI:90156 2-methylhexanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90156 UBERON:0018256 lacrimal vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018256 A vein that drains a lacrimal gland. UBERON:0018257 submucosa of digestive tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018257 Any portion of submucosa that lines the digestive tract. UBERON:0018254 skeletal musculature biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018254 UBERON:0018251 meningeal vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018251 One of the veins draining a meninix. CHEBI:16209 hypotaurocyamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16209 CHEBI:16207 3-hydroxybenzaldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16207 CHEBI:16208 3-mercaptopyruvic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16208 CHEBI:16205 biphenyl-2,3-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16205 CHEBI:16206 sn-3-O-(geranylgeranyl)glycerol 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16206 CHEBI:16204 phloroglucinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16204 CHEBI:16200 questin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16200 CHEBI:90143 N-amidinoaspartic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90143 GO:2000409 positive regulation of T cell extravasation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000409 positive regulation of T lymphocyte extravasation|positive regulation of T-cell extravasation|positive regulation of T-lymphocyte extravasation Any process that activates or increases the frequency, rate or extent of T cell extravasation. CHEBI:90171 2-hydro-beta-NAD biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90171 UBERON:0018246 thyroid vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018246 A vein that drains a thyroid gland. CHEBI:90172 c-Jun N-terminal kinase inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90172 UBERON:0018243 thymic artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018243 thymic arteries|thymic branch of internal thoracic artery A vein that supplies blood to the thymus. CHEBI:90173 6-hydro-beta-NADP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90173 CHEBI:90174 6-hydro-beta-NAD biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90174 CHEBI:90170 2-hydro-beta-NADP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90170 GO:2000401 regulation of lymphocyte migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000401 Any process that modulates the frequency, rate or extent of lymphocyte migration. GO:2000402 negative regulation of lymphocyte migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000402 Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte migration. CHEBI:31832 methyl salicylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_31832 GO:2000403 positive regulation of lymphocyte migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000403 Any process that activates or increases the frequency, rate or extent of lymphocyte migration. GO:2000404 regulation of T cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000404 regulation of T lymphocyte migration|regulation of T-cell migration|regulation of T-lymphocyte migration Any process that modulates the frequency, rate or extent of T cell migration. GO:2000405 negative regulation of T cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000405 negative regulation of T-cell migration|negative regulation of T-lymphocyte migration|negative regulation of T lymphocyte migration Any process that stops, prevents or reduces the frequency, rate or extent of T cell migration. GO:2000406 positive regulation of T cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000406 positive regulation of T-cell migration|positive regulation of T-lymphocyte migration|positive regulation of T lymphocyte migration Any process that activates or increases the frequency, rate or extent of T cell migration. GO:2000407 regulation of T cell extravasation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000407 regulation of T-cell extravasation|regulation of T-lymphocyte extravasation|regulation of T lymphocyte extravasation Any process that modulates the frequency, rate or extent of T cell extravasation. UBERON:0018247 cervical thymic artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018247 An artery that supplies a cervical thymus. GO:2000408 negative regulation of T cell extravasation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000408 negative regulation of T lymphocyte extravasation|negative regulation of T-cell extravasation|negative regulation of T-lymphocyte extravasation Any process that stops, prevents or reduces the frequency, rate or extent of T cell extravasation. CHEBI:16238 FAD biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16238 CHEBI:16239 benzyl (2R,3S)-3-hydroxy-2-methylbutanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16239 CHEBI:16236 ethanol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16236 GO:2000400 positive regulation of thymocyte aggregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000400 positive regulation of immature T cell aggregation|positive regulation of thymic lymphocyte aggregation|positive regulation of T cell precursor aggregation|positive regulation of immature T-lymphocyte aggregation|positive regulation of immature T-cell aggregation Any process that activates or increases the frequency, rate or extent of thymocyte aggregation. CHEBI:16237 4-chlorophenylacetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16237 CHEBI:16234 hydroxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16234 CHEBI:16235 guanine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16235 CHEBI:16232 N(6)-acyl-L-lysine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16232 CHEBI:16233 (S)-cheilanthifoline biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16233 CHEBI:16230 5-hydroxypentanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16230 CHEBI:16231 cis-4-hydroxy-D-proline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16231 CHEBI:90176 2,5-dihydroxybenzoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90176 UBERON:0018234 stroma of pancreas biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018234 pancreatic stroma A stroma that is part of a pancreas. UBERON:0018235 capsule of pancreas biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018235 pancreatic capsule A capsule that divides the parenchyma of the pancreas into lobes and lobules UBERON:0018232 axillary sweat gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018232 axillary apocrine sweat gland|sweat gland of axilla A sweat gland that is part of a axilla. CHEBI:90162 2,3-epoxy-2,3-dihydrobenzoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90162 CHEBI:90163 beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90163 GO:2000412 positive regulation of thymocyte migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000412 positive regulation of immature T cell migration|positive regulation of thymic lymphocyte migration|positive regulation of immature T lymphocyte migration|positive regulation of immature T-cell migration|positive regulation of immature T-lymphocyte migration Any process that activates or increases the frequency, rate or extent of thymocyte migration. GO:2000413 regulation of fibronectin-dependent thymocyte migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000413 regulation of fibronectin-dependent immature T cell migration|regulation of fibronectin-dependent thymic lymphocyte migration|regulation of fibronectin-dependent immature T lymphocyte migration|regulation of fibronectin-dependent immature T-cell migration|regulation of fibronectin-dependent immature T-lymphocyte migration Any process that modulates the frequency, rate or extent of fibronectin-dependent thymocyte migration. GO:2000414 negative regulation of fibronectin-dependent thymocyte migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000414 negative regulation of fibronectin-dependent immature T-cell migration|negative regulation of fibronectin-dependent immature T-lymphocyte migration|negative regulation of fibronectin-dependent immature T cell migration|negative regulation of fibronectin-dependent thymic lymphocyte migration|negative regulation of fibronectin-dependent immature T lymphocyte migration Any process that stops, prevents or reduces the frequency, rate or extent of fibronectin-dependent thymocyte migration. GO:2000415 positive regulation of fibronectin-dependent thymocyte migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000415 positive regulation of fibronectin-dependent immature T-cell migration|positive regulation of fibronectin-dependent immature T-lymphocyte migration|positive regulation of fibronectin-dependent immature T cell migration|positive regulation of fibronectin-dependent thymic lymphocyte migration|positive regulation of fibronectin-dependent immature T lymphocyte migration Any process that activates or increases the frequency, rate or extent of fibronectin-dependent thymocyte migration. GO:2000416 regulation of eosinophil migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000416 Any process that modulates the frequency, rate or extent of eosinophil migration. UBERON:0018238 dorsal column nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018238 dorsal column nuclei A nucleus that contain secondary neurons of the dorsal column-medial lemniscus pathway, which carries fine touch and proprioceptive information from the body to the brain. Examples: gracile nucleus, cuneat nucleus, nucleus of Bishoff. UBERON:0018239 rhombomere boundary biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018239 rhombomere junction A boundary delimiting a rhombomere. GO:2000417 negative regulation of eosinophil migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000417 Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil migration. GO:2000418 positive regulation of eosinophil migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000418 Any process that activates or increases the frequency, rate or extent of eosinophil migration. UBERON:0018237 dorsal column-medial lemniscus pathway biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018237 DCML pathway|dorsal column-medial lemniscus tract|posterior column pathway|dorsal column|DCML|dorsal column-medial lemniscus pathway|dorsal column-medial lemniscus system|medial lemniscus tracts|posterior column-medial lemniscus system|dorsal column tract|posterior column/medial leminscus pathway|posterior column-medial leminscus pathway A sensory tract originating in the spinal cord responsible for transmitting fine touch, vibration and conscious proprioceptive information from the body to the cerebral cortex. The components include the fasciculus gracilis and fasciculus cuneatus. GO:2000419 regulation of eosinophil extravasation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000419 Any process that modulates the frequency, rate or extent of eosinophil extravasation. CHEBI:16229 3beta-hydroxy-5beta-pregnan-20-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16229 CHEBI:16227 pyridine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16227 CHEBI:16228 2,2-dialkylglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16228 GO:2000410 regulation of thymocyte migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000410 regulation of thymic lymphocyte migration|regulation of immature T lymphocyte migration|regulation of immature T-cell migration|regulation of immature T-lymphocyte migration|regulation of immature T cell migration Any process that modulates the frequency, rate or extent of thymocyte migration. CHEBI:16225 S-formylglutathione biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16225 GO:2000411 negative regulation of thymocyte migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000411 negative regulation of immature T-lymphocyte migration|negative regulation of immature T cell migration|negative regulation of thymic lymphocyte migration|negative regulation of immature T lymphocyte migration|negative regulation of immature T-cell migration Any process that stops, prevents or reduces the frequency, rate or extent of thymocyte migration. CHEBI:16226 limonin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16226 CHEBI:16223 dimethylarsinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16223 CHEBI:16224 alpha-D-mannopyranuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16224 CHEBI:16221 sn-glycerol 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16221 CHEBI:16222 D-galacto-hexodialdose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16222 CHEBI:90164 N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90164 CHEBI:16220 coniferin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16220 CHEBI:90165 N-hexanoylphytosphingosine 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90165 CHEBI:90167 dTDP-2,3-dehydro-2,6-dideoxy-4-keto-alpha-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90167 IAO:0000428 requires discussion biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/IAO_0000428 A term that is metadata complete, has been reviewed, and problems have been identified that require discussion before release. Such a term requires editor note(s) to identify the outstanding issues. GO:0090404 pollen tube tip biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090404 The region at growing end of the pollen tube cell, where polarized growth occurs. GO:0090405 unicellular trichome branch biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090405 A cell projection part that is a branch of a unicellular trichome. GO:0090402 oncogene-induced cell senescence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090402 OIS A cellular senescence process associated with the dismantling of a cell as a response to oncogenic stress, such as the activation of the Ras oncogenic family. GO:0090403 oxidative stress-induced premature senescence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090403 A cellular senescence process associated with the dismantling of a cell as a response to oxidative stress, e.g. high levels of reactive oxygen species, such as superoxide anions, hydrogen peroxide, and hydroxyl radicals. GO:0090408 phloem nitrate loading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090408 The process of loading nitrate into the sieve tube or companion cell of the phloem for long distance transport from source to sink. GO:0090409 malonyl-CoA synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090409 MetaCyc:RXN-12359|EC:6.2.1.n3|RHEA:32139 Catalysis of the reaction: malonate + ATP + coenzyme A = malonyl-CoA + AMP + diphosphate. GO:0090406 pollen tube biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090406 A tubular cell projection that is part of a pollen tube cell and extends from a pollen grain. GO:0090407 organophosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090407 The chemical reactions and pathways resulting in the biosynthesis of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose. GO:0090400 stress-induced premature senescence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090400 SIPS A cellular senescence process associated with the dismantling of a cell as a response to environmental factors such as hydrogen peroxide or X-rays. GO:0090401 obsolete viral-induced premature senescence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090401 OBSOLETE. A cellular senescence process associated with the dismantling of a cell as a response to viral infection. GO:0090415 7-hydroxymethyl chlorophyll a reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090415 Catalysis of the reaction: 7-hydroxymethyl chlorophyll a + 2 reduced ferredoxin + 2 H+ chlorophyll a + 2 oxidized ferredoxin + H2O. GO:0090416 nicotinate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090416 Reactome:R-HSA-8869603 Enables the transfer of nicotinate from one side of a membrane to the other. GO:0090413 obsolete negative regulation of transcription from RNA polymerase II promoter involved in fatty acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090413 negative regulation of transcription from RNA polymerase II promoter involved in fatty acid biosynthetic process OBSOLETE. Any negative regulation of transcription from RNA polymerase II promoter that is involved in fatty acid biosynthetic process. GO:0090414 molybdate ion export from vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090414 The directed movement of molybdate ions out of the vacuole. GO:0090419 negative regulation of transcription involved in G2/M transition of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090419 negative regulation of transcription from RNA polymerase II promoter during G2/M transition of the mitotic cell cycle|down-regulation of transcription from RNA polymerase II promoter during the G2/M transition of the mitotic cell cycle Any process that inhibits or decreases the frequency, rate or extent of transcription of target genes that are transcribed as part of the G2/M transition of the mitotic cell cycle. GO:0090417 N-methylnicotinate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090417 N-methylnicotinate transporter activity Enables the transfer of N-methylnicotinate from one side of a membrane to the other. GO:0090418 obsolete positive regulation of transcription involved in S-phase of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090418 activation of transcription involved in S phase of mitotic cell cycle|positive regulation of transcription from RNA polymerase II promoter during S phase of the mitotic cell cycle|up-regulation of S phase specific transcription in the mitotic cell cycle|positive regulation of transcription involved in S-phase of mitotic cell cycle|up-regulation of transcription involved in S phase of mitotic cell cycle|activation of S phase specific transcription in the mitotic cell cycle|positive regulation of S phase specific transcription in the mitotic cell cycle|up-regulation of transcription from RNA polymerase II promoter during S phase of the mitotic cell cycle|activation of transcription from RNA polymerase II promoter during S phase of the mitotic cell cycle OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription of target genes that are transcribed as part of the S phase of the mitotic cell cycle. GO:0090411 brassinosteroid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090411 Interacting selectively and non-covalently with a brassinosteroid. GO:0090412 obsolete positive regulation of transcription from RNA polymerase II promoter involved in fatty acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090412 positive regulation of transcription from RNA polymerase II promoter involved in fatty acid biosynthetic process OBSOLETE. Any positive regulation of transcription from RNA polymerase II promoter that is involved in fatty acid biosynthetic process. GO:0090410 malonate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090410 The chemical reactions and pathways resulting in the breakdown of malonate, the propanedioate ion. CHEBI:90189 alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-beta-D-GlcNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-Cer(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90189 UBERON_CORE:conduit_for conduit for biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/uberon/core#conduit_for conduit_for x is a conduit for y iff y passes through the lumen of x. UBERON:0018278 epidermal egg tooth biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018278 Epidermal outgrowth that facilitates breaking of the eggshell in archosaurs and monotremes. UBERON:0018276 egg tooth biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018276 A protuberence or true tooth that is used during hatching to break the eggshell. GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905000 regulation of electrocardiogram QRS complex|regulation of atrial repolarization Any process that modulates the frequency, rate or extent of membrane repolarization during atrial cardiac muscle cell action potential. GO:1905001 negative regulation of membrane repolarization during atrial cardiac muscle cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905001 down regulation of electrocardiogram QRS complex|downregulation of membrane repolarization during atrial cardiac muscle cell action potential|negative regulation of atrial repolarization|downregulation of electrocardiogram QRS complex|down-regulation of atrial repolarization|down regulation of membrane repolarization during atrial cardiac muscle cell action potential|inhibition of membrane repolarization during atrial cardiac muscle cell action potential|negative regulation of electrocardiogram QRS complex|down-regulation of electrocardiogram QRS complex|inhibition of atrial repolarization|down regulation of atrial repolarization|inhibition of electrocardiogram QRS complex|down-regulation of membrane repolarization during atrial cardiac muscle cell action potential|downregulation of atrial repolarization Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during atrial cardiac muscle cell action potential. GO:1905002 positive regulation of membrane repolarization during atrial cardiac muscle cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905002 up regulation of membrane repolarization during atrial cardiac muscle cell action potential|positive regulation of atrial repolarization|activation of atrial repolarization|up regulation of electrocardiogram QRS complex|upregulation of membrane repolarization during atrial cardiac muscle cell action potential|positive regulation of electrocardiogram QRS complex|up-regulation of atrial repolarization|activation of electrocardiogram QRS complex|up-regulation of membrane repolarization during atrial cardiac muscle cell action potential|activation of membrane repolarization during atrial cardiac muscle cell action potential|upregulation of atrial repolarization|up-regulation of electrocardiogram QRS complex|upregulation of electrocardiogram QRS complex|up regulation of atrial repolarization Any process that activates or increases the frequency, rate or extent of membrane repolarization during atrial cardiac muscle cell action potential. GO:1905003 picolinic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905003 picolinic acid metabolism|picolinate metabolism The chemical reactions and pathways involving picolinic acid. OBO:GOCHE_22676 substance with auxin role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_22676 CHEBI:16182 2-methylbutanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16182 CHEBI:16183 methane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16183 CHEBI:16180 N-acylglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16180 CHEBI:16181 1-amino-1-deoxy-scyllo-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16181 GO:2000467 positive regulation of glycogen (starch) synthase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000467 positive regulation of UDP-glucose:glycogen 4-alpha-D-glucosyltransferase activity|positive regulation of UDPglucose:glycogen 4-alpha-D-glucosyltransferase activity|positive regulation of uridine diphosphoglucose-glycogen glucosyltransferase activity|positive regulation of UDP-glucose-glycogen glucosyltransferase activity|positive regulation of UDP-glycogen synthase activity|positive regulation of UDPG-glycogen transglucosylase activity|positive regulation of glycogen (starch) synthetase activity|positive regulation of UDPG-glycogen synthetase activity Any process that activates or increases the frequency, rate or extent of glycogen (starch) synthase activity. CHEBI:65113 5''-phosphoribostamycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65113 GO:2000468 regulation of peroxidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000468 regulation of oxyperoxidase activity|regulation of donor:hydrogen-peroxide oxidoreductase activity|regulation of peroxidase reaction Any process that modulates the frequency, rate or extent of peroxidase activity. CHEBI:65114 2-oxo-3-(5-oxofuran-2-ylidene)propanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65114 GO:2000469 negative regulation of peroxidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000469 negative regulation of donor:hydrogen-peroxide oxidoreductase activity|negative regulation of peroxidase reaction|negative regulation of oxyperoxidase activity Any process that stops, prevents or reduces the frequency, rate or extent of peroxidase activity. CHEBI:65115 3-oxoicosanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65115 CHEBI:65116 N-acetyl-alpha-D-glucosaminyl-1-diphospho-trans,polycis-decaprenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65116 CHEBI:65110 butirosin B biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65110 CHEBI:65111 3-substituted propionyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65111 UBERON:0018303 adrenal tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018303 adrenal gland tissue Tissue that is part of some adrenal gland CHEBI:111544 2'-hydroxyrifampicin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_111544 CHEBI:135511 rebeccamycin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_135511 GO:2000460 obsolete regulation of eukaryotic cell surface binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000460 regulation of eukaryotic cell surface binding OBSOLETE. Any process that modulates the frequency, rate or extent of eukaryotic cell surface binding. UBERON:0008987 renal parenchyma biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008987 kidney parenchyma|parenchyma of kidney The functional tissue of the kidney, consisting of the nephrons. GO:2000461 obsolete negative regulation of eukaryotic cell surface binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000461 negative regulation of eukaryotic cell surface binding OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of eukaryotic cell surface binding. GO:2000462 obsolete positive regulation of eukaryotic cell surface binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000462 positive regulation of eukaryotic cell surface binding OBSOLETE. Any process that activates or increases the frequency, rate or extent of eukaryotic cell surface binding. UBERON:0008989 submocosal esophageal gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008989 mucous gland of submucosa of esophagus|glandulae oesophageae|esophageal gland One of the racemose glands in the walls of the esophagus that in humans are small and serve principally to lubricate the food but in some birds secrete a milky fluid on which the young are fed. GO:2000463 positive regulation of excitatory postsynaptic potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000463 positive regulation of EPSP|positive regulation of excitatory post-synaptic membrane potential Any process that enhances the establishment or increases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential. CHEBI:65117 CDP-N,N-dimethylethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65117 CHEBI:65118 C20 3-dehydrosphinganine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65118 GO:2000464 positive regulation of astrocyte chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000464 Any process that activates or increases the frequency, rate or extent of astrocyte chemotaxis. GO:2000465 regulation of glycogen (starch) synthase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000465 regulation of UDPglucose:glycogen 4-alpha-D-glucosyltransferase activity|regulation of uridine diphosphoglucose-glycogen glucosyltransferase activity|regulation of UDPG-glycogen transglucosylase activity|regulation of glycogen (starch) synthetase activity|regulation of UDPG-glycogen synthetase activity|regulation of UDP-glucose:glycogen 4-alpha-D-glucosyltransferase activity|regulation of UDP-glycogen synthase activity|regulation of UDP-glucose-glycogen glucosyltransferase activity Any process that modulates the frequency, rate or extent of glycogen (starch) synthase activity. CHEBI:111542 validone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_111542 GO:2000466 negative regulation of glycogen (starch) synthase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000466 negative regulation of UDPG-glycogen synthetase activity|negative regulation of UDP-glucose:glycogen 4-alpha-D-glucosyltransferase activity|negative regulation of UDP-glucose-glycogen glucosyltransferase activity|negative regulation of UDP-glycogen synthase activity|negative regulation of UDPG-glycogen transglucosylase activity|negative regulation of glycogen (starch) synthetase activity|negative regulation of UDPglucose:glycogen 4-alpha-D-glucosyltransferase activity|negative regulation of uridine diphosphoglucose-glycogen glucosyltransferase activity Any process that stops, prevents or reduces the frequency, rate or extent of glycogen (starch) synthase activity. CHEBI:16179 retinyl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16179 CHEBI:16177 vicianose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16177 CHEBI:16175 cholest-4-en-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16175 CHEBI:16176 D-ornithine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16176 CHEBI:16173 aldehydo-N-acyl-D-mannosamine 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16173 CHEBI:16174 dADP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16174 CHEBI:16171 NMN zwitterion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16171 CHEBI:16172 neryl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16172 CHEBI:16170 mercury(0) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16170 GO:2000478 positive regulation of metanephric glomerular visceral epithelial cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000478 positive regulation of metanephric podocyte development Any process that activates or increases the frequency, rate or extent of metanephric glomerular visceral epithelial cell development. GO:2000479 regulation of cAMP-dependent protein kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000479 regulation of PKA|regulation of cAMP-dependent protein kinase, intrinsic catalyst activity|regulation of 3',5' cAMP-dependent protein kinase activity|regulation of ATP:protein phosphotransferase (cAMP-dependent) activity|regulation of 3',5'-cAMP-dependent protein kinase activity|regulation of protein kinase A activity|regulation of AMPK|regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity|regulation of STK22|regulation of cyclic AMP-dependent protein kinase activity|regulation of PKA C Any process that modulates the frequency, rate or extent of cAMP-dependent protein kinase activity. CHEBI:41131 crotonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_41131 CHEBI:65121 isopentenyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65121 CHEBI:65122 3-substituted propionyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65122 GO:2000470 positive regulation of peroxidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000470 positive regulation of oxyperoxidase activity|positive regulation of donor:hydrogen-peroxide oxidoreductase activity|positive regulation of peroxidase reaction Any process that activates or increases the frequency, rate or extent of peroxidase activity. GO:2000471 regulation of hematopoietic stem cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000471 regulation of hemopoietic stem cell migration Any process that modulates the frequency, rate or extent of hematopoietic stem cell migration. GO:2000472 negative regulation of hematopoietic stem cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000472 negative regulation of hemopoietic stem cell migration Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell migration. GO:2000473 positive regulation of hematopoietic stem cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000473 positive regulation of hemopoietic stem cell migration Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell migration. GO:2000474 regulation of opioid receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000474 regulation of opioid receptor signalling pathway Any process that modulates the frequency, rate or extent of opioid receptor signaling pathway. CHEBI:41139 N,N,N-trimethylglycinium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_41139 GO:2000475 negative regulation of opioid receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000475 negative regulation of opioid receptor signalling pathway Any process that stops, prevents or reduces the frequency, rate or extent of opioid receptor signaling pathway. GO:2000476 positive regulation of opioid receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000476 positive regulation of opioid receptor signalling pathway Any process that activates or increases the frequency, rate or extent of opioid receptor signaling pathway. GO:2000477 regulation of metanephric glomerular visceral epithelial cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000477 regulation of metanephric podocyte development Any process that modulates the frequency, rate or extent of metanephric glomerular visceral epithelial cell development. CHEBI:16168 6-hydroxynicotinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16168 OIO:hasRelatedSynonym has_related_synonym biolink:OntologyClass go-plus http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym CHEBI:16169 homogentisate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16169 CHEBI:16166 2-caffeoylisocitric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16166 CHEBI:16164 pyrogallol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16164 CHEBI:16165 D-glucono-1,4-lactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16165 CHEBI:16162 o-orsellinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16162 CHEBI:16163 S-carboxymethyl-L-cysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16163 GO:2000489 regulation of hepatic stellate cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000489 Any process that modulates the frequency, rate or extent of hepatic stellate cell activation. CHEBI:65136 (4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65136 CHEBI:65131 (6Z,9Z,12Z,15Z,18Z,21Z)-3-oxotetracosahexaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65131 CHEBI:65132 (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65132 GO:2000481 positive regulation of cAMP-dependent protein kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000481 positive regulation of cyclic AMP-dependent protein kinase activity|positive regulation of cAMP-dependent protein kinase, intrinsic catalyst activity|positive regulation of 3',5' cAMP-dependent protein kinase activity|positive regulation of protein kinase A activity|positive regulation of STK22|positive regulation of PKA C|positive regulation of PKA|positive regulation of ATP:protein phosphotransferase (cAMP-dependent) activity|positive regulation of 3',5'-cAMP-dependent protein kinase activity|positive regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity|positive regulation of AMPK Any process that activates or increases the frequency, rate or extent of cAMP-dependent protein kinase activity. GO:2000482 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2000482 GO:2000483 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2000483 GO:2000484 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2000484 CHEBI:65139 (2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65139 GO:2000485 regulation of glutamine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000485 regulation of L-glutamine transport Any process that modulates the frequency, rate or extent of glutamine transport. GO:2000486 negative regulation of glutamine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000486 negative regulation of L-glutamine transport Any process that stops, prevents or reduces the frequency, rate or extent of glutamine transport. UBERON:0008969 dental follicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008969 dental sac|tooth follicle A sac containing the developing tooth and its odontogenic organ. The dental follicle (DF) differentiates into the periodontal ligament. In addition, it may be the precursor of other cells of the periodontium, including osteoblasts, cementoblasts and fibroblasts. They develop into the alveolar bone, the cementum with Sharpey's fibers and the periodontal ligament fibers respectively. GO:2000487 positive regulation of glutamine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000487 positive regulation of L-glutamine transport Any process that activates or increases the frequency, rate or extent of glutamine transport. GO:2000488 positive regulation of brassinosteroid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000488 positive regulation of brassinosteroid synthesis|positive regulation of brassinosteroid formation|positive regulation of brassinosteroid biosynthesis|positive regulation of brassinosteroid anabolism Any process that activates or increases the frequency, rate or extent of brassinosteroid biosynthetic process. CHEBI:16199 urea biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16199 CHEBI:16197 N-acylsphingosine 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16197 UBERON:0008962 forelimb bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008962 wing bone|free forelimb bone A bone that is part of a forelimb region. Examples: humerus, any of the phalanges. Counter-example: scapula (a bone of the pectoral girdle). Note that we consider the forelimb to end at the shoulder. GO:2000480 negative regulation of cAMP-dependent protein kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000480 negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity|negative regulation of 3',5' cAMP-dependent protein kinase activity|negative regulation of protein kinase A activity|negative regulation of STK22|negative regulation of PKA C|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity|negative regulation of PKA|negative regulation of 3',5'-cAMP-dependent protein kinase activity|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity|negative regulation of AMPK|negative regulation of cyclic AMP-dependent protein kinase activity Any process that stops, prevents or reduces the frequency, rate or extent of cAMP-dependent protein kinase activity. CHEBI:16196 oleic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16196 CHEBI:16193 3-hydroxybenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16193 CHEBI:16192 2'-deoxyguanosine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16192 CHEBI:16190 cis-cyclohexa-3,5-diene-1,2-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16190 CHEBI:80774 tauroursodeoxycholic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_80774 GO:2000492 regulation of interleukin-18-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000492 regulation of interleukin-18-mediated signalling pathway Any process that modulates the frequency, rate or extent of interleukin-18-mediated signaling pathway. GO:2000493 negative regulation of interleukin-18-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000493 negative regulation of interleukin-18-mediated signalling pathway Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-18-mediated signaling pathway. GO:2000494 positive regulation of interleukin-18-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000494 positive regulation of interleukin-18-mediated signalling pathway Any process that activates or increases the frequency, rate or extent of interleukin-18-mediated signaling pathway. GO:2000495 regulation of cell proliferation involved in compound eye morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000495 Any process that modulates the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis. GO:2000496 negative regulation of cell proliferation involved in compound eye morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000496 Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis. CHEBI:41117 N-benzylformamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_41117 GO:2000497 positive regulation of cell proliferation involved in compound eye morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000497 Any process that activates or increases the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis. GO:2000498 obsolete regulation of induction of apoptosis in response to chemical stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000498 regulation of induction of apoptosis in response to chemical stimulus|regulation of induction of apoptosis in response to chemical substance OBSOLETE. Any process that modulates the frequency, rate or extent of induction of apoptosis in response to chemical stimulus. GO:2000499 obsolete negative regulation of induction of apoptosis in response to chemical stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000499 negative regulation of induction of apoptosis in response to chemical substance|negative regulation of induction of apoptosis in response to chemical stimulus OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of induction of apoptosis in response to chemical stimulus. CHEBI:16188 octan-1-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16188 CHEBI:16189 sulfate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16189 CHEBI:16187 1-piperideine-2-carboxylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16187 GO:2000490 negative regulation of hepatic stellate cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000490 Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell activation. CHEBI:16184 7-O-acetylsalutaridinol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16184 CHEBI:16185 N(5)-acyl-L-ornithine ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16185 UBERON:0008951 left lung lobe biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008951 lobe of left lung|lobe of the left lung A lobe of lung that is part of a left lung. GO:2000491 positive regulation of hepatic stellate cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000491 Any process that activates or increases the frequency, rate or extent of hepatic stellate cell activation. GO:2000423 negative regulation of eosinophil chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000423 Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil chemotaxis. CHEBI:111509 alpha-L-colitosyl-(1->2)-beta-D-galactosyl-(1->3)-N-acetyl-D-glucosamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_111509 GO:2000424 positive regulation of eosinophil chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000424 Any process that activates or increases the frequency, rate or extent of eosinophil chemotaxis. CHEBI:80788 1,4-cineole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_80788 GO:2000425 regulation of apoptotic cell clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000425 regulation of programmed cell clearance|regulation of apoptotic cell removal|regulation of efferocytosis Any process that modulates the frequency, rate or extent of apoptotic cell clearance. GO:2000426 negative regulation of apoptotic cell clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000426 negative regulation of programmed cell clearance|negative regulation of efferocytosis|negative regulation of apoptotic cell removal Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic cell clearance. GO:2000427 positive regulation of apoptotic cell clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000427 positive regulation of apoptotic cell removal|positive regulation of programmed cell clearance|positive regulation of efferocytosis Any process that activates or increases the frequency, rate or extent of apoptotic cell clearance. CHEBI:111504 validoxylamine A 7'-phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_111504 GO:2000428 regulation of neutrophil aggregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000428 regulation of neutrophilic leukocyte aggregation|regulation of neutrophil leucocyte aggregation|regulation of neutrocyte aggregation Any process that modulates the frequency, rate or extent of neutrophil aggregation. CHEBI:111505 validoxylamine A(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_111505 GO:2000429 negative regulation of neutrophil aggregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000429 negative regulation of neutrophil leucocyte aggregation|negative regulation of neutrocyte aggregation|negative regulation of neutrophilic leukocyte aggregation Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil aggregation. CHEBI:65156 Man-beta1-2-Ins-1-P-Cer(d18:0/24:0)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65156 CHEBI:111503 validamine 7-phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_111503 CHEBI:90118 tricosanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90118 GO:2000420 negative regulation of eosinophil extravasation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000420 Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil extravasation. GO:2000421 positive regulation of eosinophil extravasation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000421 Any process that activates or increases the frequency, rate or extent of eosinophil extravasation. CHEBI:90119 (2E)-tricosenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90119 CHEBI:16137 chondroitin D-glucuronate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16137 GO:2000422 regulation of eosinophil chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000422 Any process that modulates the frequency, rate or extent of eosinophil chemotaxis. CHEBI:16138 2-deoxy-D-gluconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16138 CHEBI:16135 isobutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16135 CHEBI:16136 hydrogen sulfide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16136 CHEBI:16133 cyclopentanol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16133 CHEBI:16134 ammonia biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16134 CHEBI:16132 2-deoxy-D-ribose 5-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16132 CHEBI:16130 DDT biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16130 GO:2000434 regulation of protein neddylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000434 regulation of RUB1-protein conjugation Any process that modulates the frequency, rate or extent of protein neddylation. GO:2000435 negative regulation of protein neddylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000435 negative regulation of RUB1-protein conjugation Any process that stops, prevents or reduces the frequency, rate or extent of protein neddylation. GO:2000436 positive regulation of protein neddylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000436 positive regulation of RUB1-protein conjugation Any process that activates or increases the frequency, rate or extent of protein neddylation. GO:2000437 regulation of monocyte extravasation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000437 Any process that modulates the frequency, rate or extent of monocyte extravasation. GO:2000438 negative regulation of monocyte extravasation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000438 Any process that stops, prevents or reduces the frequency, rate or extent of monocyte extravasation. GO:2000439 positive regulation of monocyte extravasation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000439 Any process that activates or increases the frequency, rate or extent of monocyte extravasation. GO:2000430 positive regulation of neutrophil aggregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000430 positive regulation of neutrophilic leukocyte aggregation|positive regulation of neutrophil leucocyte aggregation|positive regulation of neutrocyte aggregation Any process that activates or increases the frequency, rate or extent of neutrophil aggregation. CHEBI:16128 dTDP-4-dehydro-6-deoxy-alpha-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16128 GO:2000431 regulation of cytokinesis, actomyosin contractile ring assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000431 regulation of contractile ring assembly Any process that modulates the frequency, rate or extent of cytokinesis, actomyosin contractile ring assembly. GO:2000432 negative regulation of cytokinesis, actomyosin contractile ring assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000432 negative regulation of contractile ring assembly Any process that stops, prevents or reduces the frequency, rate or extent of cytokinesis, actomyosin contractile ring assembly. CHEBI:16126 3-(4-deoxy-beta-D-gluc-4-enosyluronic acid)-N-acetyl-D-glucosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16126 CHEBI:90109 L-3-sulfolactaldehyde(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90109 GO:2000433 positive regulation of cytokinesis, actomyosin contractile ring assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000433 positive regulation of contractile ring assembly Any process that activates or increases the frequency, rate or extent of cytokinesis, actomyosin contractile ring assembly. CHEBI:16124 alpha-L-fucosyl-(1->2)-beta-D-galactosyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16124 CHEBI:16125 hexadecan-1-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16125 CHEBI:16122 3-(4-hydroxy-3,5-diiodophenyl)lactic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16122 CHEBI:90104 D-3-sulfolactaldehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90104 CHEBI:16123 6-oxocineole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16123 CHEBI:16120 5-oxopentanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16120 CHEBI:16121 N-acetyl-beta-D-galactosaminyl-(1->4)-alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16121 CHEBI:16160 O-succinyl-L-homoserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16160 CHEBI:65172 ximelagatran biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65172 CHEBI:16161 CoA-disulfide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16161 CHEBI:65173 iloperidone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65173 UBERON:0018321 foramen for glossopharyngeal nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018321 Foramen that allows the passge of the glossopharyngeal nerve (cranial nerve IX). GO:2000445 positive regulation of toll-like receptor 21 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000445 positive regulation of TLR21 signaling pathway|positive regulation of toll-like receptor 21 signalling pathway Any process that activates or increases the frequency, rate or extent of toll-like receptor 21 signaling pathway. GO:2000446 regulation of macrophage migration inhibitory factor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000446 regulation of MIF signaling pathway|regulation of macrophage migration inhibitory factor signalling pathway Any process that modulates the frequency, rate or extent of macrophage migration inhibitory factor signaling pathway. CHEBI:31755 L-4-hydroxyphenylglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31755 GO:2000447 negative regulation of macrophage migration inhibitory factor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000447 negative regulation of macrophage migration inhibitory factor signalling pathway|negative regulation of MIF signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of macrophage migration inhibitory factor signaling pathway. GO:2000448 positive regulation of macrophage migration inhibitory factor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000448 positive regulation of macrophage migration inhibitory factor signalling pathway|positive regulation of MIF signaling pathway Any process that activates or increases the frequency, rate or extent of macrophage migration inhibitory factor signaling pathway. GO:2000449 regulation of CD8-positive, alpha-beta T cell extravasation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000449 Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell extravasation. CHEBI:111522 valienone 7-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_111522 CHEBI:111523 validone 7-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_111523 GO:2000440 regulation of toll-like receptor 15 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000440 regulation of TLR15 signaling pathway|regulation of toll-like receptor 15 signalling pathway Any process that modulates the frequency, rate or extent of toll-like receptor 15 signaling pathway. GO:2000441 negative regulation of toll-like receptor 15 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000441 negative regulation of toll-like receptor 15 signalling pathway|negative regulation of TLR15 signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of toll-like receptor 15 signaling pathway. GO:2000442 positive regulation of toll-like receptor 15 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000442 positive regulation of toll-like receptor 15 signalling pathway|positive regulation of TLR15 signaling pathway Any process that activates or increases the frequency, rate or extent of toll-like receptor 15 signaling pathway. GO:2000443 regulation of toll-like receptor 21 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000443 regulation of TLR21 signaling pathway|regulation of toll-like receptor 21 signalling pathway Any process that modulates the frequency, rate or extent of toll-like receptor 21 signaling pathway. CHEBI:16159 sulochrin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16159 GO:2000444 negative regulation of toll-like receptor 21 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000444 negative regulation of TLR21 signaling pathway|negative regulation of toll-like receptor 21 signalling pathway Any process that stops, prevents or reduces the frequency, rate or extent of toll-like receptor 21 signaling pathway. CHEBI:111521 valienone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_111521 CHEBI:16157 D-arabinonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16157 CHEBI:16158 steroid sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16158 CHEBI:16155 myo-inositol 1,3,4,6-tetrakisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16155 CHEBI:16153 N-acetyllactosamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16153 CHEBI:16154 L-gulonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16154 CHEBI:16151 3,4-dihydrocoumarin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16151 CHEBI:16152 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16152 CHEBI:16150 benzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16150 CHEBI:65180 GDP(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65180 GO:2000456 negative regulation of T-helper 17 cell extravasation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000456 Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell extravasation. CHEBI:111519 2,3-dichloromuconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_111519 GO:2000457 positive regulation of T-helper 17 cell extravasation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000457 Any process that activates or increases the frequency, rate or extent of T-helper 17 cell extravasation. GO:2000458 regulation of astrocyte chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000458 Any process that modulates the frequency, rate or extent of astrocyte chemotaxis. GO:2000459 negative regulation of astrocyte chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000459 Any process that stops, prevents or reduces the frequency, rate or extent of astrocyte chemotaxis. CHEBI:111511 (beta-D-glucopyranosyloxymethyl)deoxyuridine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_111511 PR:000003112 NFAT protein biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000003112 A protein that contains a Rel homology domain (RHD) (Pfam:PF00554) followed by an IPT/TIG domain (Pfam:PF01833). PR:000003113 nuclear factor of activated T-cells, cytoplasmic 1 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000003113 NF-ATc|NFATC1|NFATc1|NFATc|NF-ATc1|NFAT transcription complex cytosolic component|NFAT2 An NFAT protein that is a translation product of the human NFATC1 gene or a 1:1 ortholog thereof. GO:2000450 negative regulation of CD8-positive, alpha-beta T cell extravasation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000450 Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell extravasation. UBERON:0008998 vasculature of brain biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008998 cerebrovascular system|brain vasculature|intracerebral vasculature System pertaining to blood vessels in the brain. GO:2000451 positive regulation of CD8-positive, alpha-beta T cell extravasation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000451 Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell extravasation. GO:2000452 regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000452 Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation. GO:2000453 negative regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000453 Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation. GO:2000454 positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000454 Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation. CHEBI:31763 laricitrin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31763 CHEBI:16148 heptadecane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16148 GO:2000455 regulation of T-helper 17 cell extravasation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000455 Any process that modulates the frequency, rate or extent of T-helper 17 cell extravasation. CHEBI:16146 maleamate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16146 CHEBI:16147 11-O-demethyl-17-O-deacetylvindoline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16147 CHEBI:16144 selenophosphate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16144 CHEBI:16145 3,5/4-trihydroxycyclohexane-1,2-dione biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16145 CHEBI:16142 3-dehydro-L-gulonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16142 CHEBI:16143 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16143 UBERON:0008993 habenular nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008993 nucleus habenulae|ganglion habenulae|habenular nuclei Either of the two neural nuclei within the habenula. CHEBI:16141 undecaprenyl dihydrogen phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16141 UBERON:0008995 nucleus of cerebellar nuclear complex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008995 cerebellar nucleus|deep cerebellar nucleus Four accumulations of gray substance embedded in the white substance of the cerebellum, comprising the nucleus dentatus, nucleus emboliformis, nucleus globosus, and nucleus fastigii. GO:0016466 obsolete hydrogen-translocating A-type ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016466 hydrogen-translocating A-type ATPase activity|proton-translocating A-type ATPase activity OBSOLETE. Catalysis of the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out). Found in archae. GO:0016467 obsolete hydrogen-translocating F-type ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016467 F1-ATPase activity|hydrogen-translocating F-type ATPase activity|ATP synthase|proton-translocating F-type ATPase activity OBSOLETE. Catalysis of the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out). Found in eukaryotic mitochondria and chloroplasts and in bacteria. GO:0016468 obsolete sodium-translocating F-type ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016468 sodium-translocating F-type ATPase activity|ATP synthase OBSOLETE. Catalysis of the reaction: ATP + H2O + Na+(in) = ADP + phosphate + Na+(out). Found in eukaryotic mitochondria and chloroplasts and in bacteria. UBERON:0008904 neuromast biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008904 neuromaste superficiel@fr|neuromasts|lateral line organ|neuromast organ|cyatocïde@fr|lateral line neuromast Volcano-shaped lateral line sensory organ located in characteristic positions within the skin epithelium and containing hair cells and their support elements. GO:0016469 proton-transporting two-sector ATPase complex biolink:CellularComponent go-plus goslim_pir|goslim_metagenomics http://purl.obolibrary.org/obo/GO_0016469 hydrogen-transporting two-sector ATPase complex|vacuolar hydrogen-transporting ATPase A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. The complex comprises a membrane sector (F0, V0, or A0) that carries out proton transport and a cytoplasmic compartment sector (F1, V1, or A1) that catalyzes ATP synthesis or hydrolysis. Two major types have been characterized: V-type ATPases couple ATP hydrolysis to the transport of protons across a concentration gradient, whereas F-type ATPases, also known as ATP synthases, normally run in the reverse direction to utilize energy from a proton concentration or electrochemical gradient to synthesize ATP. A third type, A-type ATPases have been found in archaea, and are closely related to eukaryotic V-type ATPases but are reversible. GO:0016462 pyrophosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016462 Reactome:R-HSA-6810472|RHEA:51724 Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments. GO:0016463 P-type zinc transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016463 MetaCyc:3.6.3.5-RXN|RHEA:20621|EC:7.2.2.12 ATP phosphohydrolase (Zn2+-exporting)|P(1B)-type ATPase activity|zinc-translocating P-type ATPase activity|Zn2+-exporting ATPase activity|zinc transmembrane transporter activity, phosphorylative mechanism|zinc exporting ATPase activity|P1B-type ATPase activity|zinc-exporting ATPase activity|Zn(2+)-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Zn2+(in) -> ADP + phosphate + Zn2+(out). GO:0016464 chloroplast protein-transporting ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016464 EC:7.4.2.4|MetaCyc:3.6.3.52-RXN AAA chloroplast protein-transporting ATPase|ATPase-coupled chloroplast protein transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the chloroplast stroma. GO:0016465 chaperonin ATPase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016465 Multisubunit protein complex with 2x7 (Type I, in most cells) or 2x8 (Type II, in Archaea) ATP-binding sites involved in maintaining an unfolded polypeptide structure before folding or to entry into mitochondria and chloroplasts. GO:0016460 myosin II complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016460 conventional myosin A myosin complex containing two class II myosin heavy chains, two myosin essential light chains and two myosin regulatory light chains. Also known as classical myosin or conventional myosin, the myosin II class includes the major muscle myosin of vertebrate and invertebrate muscle, and is characterized by alpha-helical coiled coil tails that self assemble to form a variety of filament structures. GO:0016461 unconventional myosin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016461 non-muscle myosin A portmanteau term for myosins other than myosin II. GO:0016477 cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016477 Wikipedia:Cell_migration The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms. GO:0016478 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016478 GO:0016479 negative regulation of transcription by RNA polymerase I biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016479 negative regulation of transcription from Pol I promoter|negative regulation of transcription from RNA polymerase I promoter|down-regulation of transcription from RNA polymerase I promoter|downregulation of transcription from RNA polymerase I promoter|down regulation of transcription from RNA polymerase I promoter|inhibition of transcription from RNA polymerase I promoter Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase I. GO:0016473 sodium ion-transporting F-type ATPase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016473 sodium-translocating F-type ATPase complex A sodium ion-transporting two-sector ATPase complex that catalyzes the phosphorylation of ADP to ATP. The complex comprises a membrane sector (F0) that carries out proton transport and a cytoplasmic compartment sector (F1) that catalyzes ATP synthesis by a rotational mechanism. GO:0016474 sodium ion-transporting V-type ATPase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016474 sodium-translocating V-type ATPase complex A sodium ion-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of sodium ions across a concentration gradient. The complex comprises a membrane sector (V0) that carries out proton transport and a cytoplasmic compartment sector (V1) that catalyzes ATP hydrolysis. GO:0016475 detection of nuclear:cytoplasmic ratio biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016475 interpretation of nuclear:cytoplasmic ratio|sensing of nuclear:cytoplasmic ratio The process in which the size of the nucleus with respect to its cytoplasm is sensed by a cell. GO:0016476 regulation of embryonic cell shape biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016476 shape changes of embryonic cells Any process that modulates the surface configuration of an embryonic cell. GO:0016470 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016470 GO:0016471 vacuolar proton-transporting V-type ATPase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016471 vacuolar hydrogen-translocating V-type ATPase complex A proton-transporting two-sector ATPase complex found in the vacuolar membrane, where it acts as a proton pump to mediate acidification of the vacuolar lumen. GO:0016472 sodium ion-transporting two-sector ATPase complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0016472 sodium-transporting two-sector ATPase complex A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of sodium ions across a membrane. The complex comprises a membrane sector (F0 or V0) that carries out ion transport and a cytoplasmic compartment sector (F1 or V1) that catalyzes ATP synthesis or hydrolysis. GO:0090381 regulation of heart induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090381 Any process that modulates the rate, frequency, or extent of heart induction. Heart induction is the close range interaction between mesoderm and endoderm or ectoderm that causes cells to change their fates and specify the development of the heart. GO:0090382 phagosome maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090382 A process that is carried out at the cellular level which results in the arrangement of constituent parts of a phagosome within a cell. Phagosome maturation begins with endocytosis and formation of the early phagosome and ends with the formation of the hybrid organelle, the phagolysosome. GO:0090380 seed trichome maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090380 A developmental process, independent of morphogenetic (shape) change, that is required for a seed trichome to attain its fully functional state. GO:0016448 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016448 GO:0016449 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016449 GO:0016444 somatic cell DNA recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016444 Recombination occurring within or between DNA molecules in somatic cells. GO:0016445 somatic diversification of immunoglobulins biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016445 somatic diversification of antibodies The somatic process that results in the generation of sequence diversity of immunoglobulins. GO:0016446 somatic hypermutation of immunoglobulin genes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016446 somatic hypermutation of antibody genes Mutations occurring somatically that result in amino acid changes in the rearranged V regions of immunoglobulins. GO:0016447 somatic recombination of immunoglobulin gene segments biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016447 somatic recombination of antibody gene segments The process in which immunoglobulin genes are formed through recombination of the germline genetic elements, as known as immunoglobulin gene segments, within a single locus. GO:0016440 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016440 GO:0090385 phagosome-lysosome fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090385 The creation of a phagolysosome from a phagosome and a lysosome. GO:0090386 phagosome maturation involved in apoptotic cell clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090386 A process that is carried out at the cellular level which results in the arrangement of constituent parts of a phagosome within a cell and contributes to apoptotic cell clearance. Phagosome maturation begins with endocytosis and formation of the early phagosome and ends with the formation of the hybrid organelle, the phagolysosome. GO:0016441 posttranscriptional gene silencing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016441 Wikipedia:Post_transcriptional_gene_silencing post-transcriptional gene silencing|PTGS|cosuppression|quelling The inactivation of gene expression by a posttranscriptional mechanism. GO:0090383 phagosome acidification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090383 phagosomal acidification Any process that reduces the pH of the phagosome, measured by the concentration of the hydrogen ion. GO:0016442 RISC complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016442 Wikipedia:RNA-induced_silencing_complex RNA-induced silencing complex|micro-ribonucleoprotein complex|miRNP complex A ribonucleoprotein complex that contains members of the Argonaute family of proteins, small interfering RNAs (siRNAs) or microRNAs (miRNAs), and miRNA or siRNA-complementary mRNAs, in addition to a number of accessory factors. The RISC complex is involved in posttranscriptional repression of gene expression through downregulation of translation or induction of mRNA degradation. GO:0016443 bidentate ribonuclease III activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016443 EC:3.1.26.- bidentate RNase III activity Catalysis of the digestion of double-stranded RNAs into 20 to 30-nucleotide products. These products typically associate to the RNA-induced silencing complex and serve as guide RNAs for posttranslational RNA interference. GO:0090384 phagosome-lysosome docking biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090384 lysosome recruitment to phagosome The initial attachment of a phagosome membrane to a lysosome membrane. Docking requires only that the proteins come close enough to interact and adhere. GO:0090389 phagosome-lysosome fusion involved in apoptotic cell clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090389 The creation of a phagolysosome from a phagosome and a lysosome as a part of apoptotic cell clearance. GO:0090387 phagolysosome assembly involved in apoptotic cell clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090387 The process in which a phagosome, a vesicle formed by phagocytosis, fuses with a lysosome as a part of apoptotic cell clearance. GO:0090388 phagosome-lysosome docking involved in apoptotic cell clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090388 The initial attachment of a phagosome membrane to a lysosome membrane that occurs as a part of apoptotic cell clearance. Docking requires only that the proteins come close enough to interact and adhere. GO:0090392 sepal giant cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090392 The process in which a relatively unspecialized cell acquires specialized features of a sepal giant cell. A sepal giant cell is a pavement cell that is part of the sepal epidermis and stretches one fifth the length of the sepal with a chromosome content of 16C. GO:0090393 sepal giant cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090393 sepal giant cell formation The process aimed at the progression of a sepal giant cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. GO:0090390 phagosome acidification involved in apoptotic cell clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090390 Any process that reduces the pH of the phagosome, measured by the concentration of the hydrogen ion, and occurs as a part of apoptotic cell clearance. GO:0090391 granum assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090391 grana formation A process that is carried out at the cellular level which results in the assembly of a granum. A granum is a distinct stack of lamellae seen within chloroplasts. GO:0016459 myosin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016459 A protein complex, formed of one or more myosin heavy chains plus associated light chains and other proteins, that functions as a molecular motor; uses the energy of ATP hydrolysis to move actin filaments or to move vesicles or other cargo on fixed actin filaments; has magnesium-ATPase activity and binds actin. Myosin classes are distinguished based on sequence features of the motor, or head, domain, but also have distinct tail regions that are believed to bind specific cargoes. GO:0016455 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016455 GO:0016456 X chromosome located dosage compensation complex, transcription activating biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016456 dosage compensation complex An RNA-protein complex localized to the X chromosome of males where it is required for the hyper-transcriptional activation of the X chromosome. An example of this is found in Drosophila melanogaster. GO:0016457 dosage compensation complex assembly involved in dosage compensation by hyperactivation of X chromosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016457 dosage compensation complex assembly during dosage compensation by hyperactivation of X chromosome The aggregation, arrangement and bonding together of proteins on DNA to form the complex that mediates dosage compensation on the X chromosome of the heterogametic sex, ultimately resulting in a two-fold increase in transcription from this chromosome. An example of this is found in Drosophila melanogaster. GO:0016458 gene silencing biolink:BiologicalProcess go-plus goslim_pir|goslim_drosophila http://purl.obolibrary.org/obo/GO_0016458 Wikipedia:Gene_silencing long-term maintenance of gene inactivation Any process carried out at the cellular level that results in either long-term transcriptional repression via action on chromatin structure or RNA mediated, post-transcriptional repression of gene expression. GO:0016451 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016451 GO:0090396 leaf papilla biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090396 A plant cell papilla that is part of a leaf papilla cell. GO:0016452 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016452 GO:0090397 stigma papilla biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090397 A plant cell papilla that is part of a stigma papilla cell. GO:0090394 negative regulation of excitatory postsynaptic potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090394 reduction of excitatory postsynaptic membrane potential|negative regulation of excitatory post-synaptic membrane potential|negative regulation of EPSP Any process that prevents the establishment or decreases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential. GO:0016453 C-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016453 Catalysis of the transfer of an acetyl group to a carbon atom on the acceptor molecule. GO:0090395 plant cell papilla biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090395 A cell projection that is a short, rounded projection from a plant epidermal cell. GO:0016454 C-palmitoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016454 Catalysis of the transfer of a palmitoyl group to a carbon atom on the acceptor molecule. GO:0090398 cellular senescence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090398 A cell aging process stimulated in response to cellular stress, whereby normal cells lose the ability to divide through irreversible cell cycle arrest. GO:0016450 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016450 GO:0090399 replicative senescence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090399 A cell aging process associated with the dismantling of a cell as a response to telomere shortening and/or cellular aging. CHEBI:41183 D-erythro-biopterin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_41183 CHEBI:41189 butane-1,4-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_41189 GO:0016426 tRNA (adenine) methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016426 Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing methyladenine. GO:0016427 tRNA (cytosine) methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016427 Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing methylcytosine. GO:0016428 tRNA (cytosine-5-)-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016428 Reactome:R-HSA-6785438|Reactome:R-HSA-6782388|Reactome:R-HSA-6785409|Reactome:R-HSA-6782419|Reactome:R-HSA-8932765 transfer ribonucleate cytosine 5-methyltransferase activity|S-adenosyl-L-methionine:tRNA (cytosine-5-)-methyltransferase activity|transfer RNA cytosine 5-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 5-methylcytosine. GO:0016429 tRNA (adenine-N1-)-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016429 Reactome:R-HSA-6783492|Reactome:R-HSA-6787525|Reactome:R-HSA-6787594 transfer RNA (adenine-1) methyltransferase activity|S-adenosyl-L-methionine:tRNA (adenine-N1-)-methyltransferase activity|S-adenosyl-L-methionine:tRNA (adenine-1-N-)-methyltransferase activity|transfer ribonucleate adenine 1-methyltransferase activity|adenine-1-methylase activity|1-methyladenine transfer RNA methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N1-methyladenine. GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016422 RHEA:22744|EC:2.1.1.62|MetaCyc:2.1.1.62-RXN S-adenosyl-L-methionine:mRNA (2'-O-methyladenosine-6-N-)-methyltransferase activity|messenger ribonucleate 2'-O-methyladenosine NG-methyltransferase activity|S-adenosyl-L-methionine:mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + m(7)G(5')pppAm = S-adenosyl-L-homocysteine + m(7)G(5')pppm(6)Am. UBERON:0008946 lung parenchyma biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008946 parenchyma of lung|respiratory portion of lung|pulmonary parenchyma A parenchyma that is part of a lung. GO:0016423 tRNA (guanine) methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016423 tRNA (guanosine) methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing methylguanine. UBERON:0008947 respiratory primordium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008947 GO:0016424 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016424 GO:0016425 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016425 GO:0016420 malonyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016420 Catalysis of the transfer of a malonyl (HOOC-CH2-CO-) group to an acceptor molecule. GO:0016421 CoA carboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016421 Catalysis of the joining of a carboxyl group to a molecule that is attached to CoA, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. GO:0016437 tRNA cytidylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016437 EC:2.7.7.72|MetaCyc:TRNA-CYTIDYLYLTRANSFERASE-RXN ATP(CTP)-tRNA nucleotidyltransferase|tRNA adenylyl(cytidylyl)transferase|transfer ribonucleic acid nucleotidyl transferase|transfer ribonucleic adenylyl (cytidylyl) transferase|CTP:tRNA cytidylyltransferase activity|transfer ribonucleic-terminal trinucleotide nucleotidyltransferase|-C-C-A pyrophosphorylase|transfer ribonucleate adenylyltransferase|CTP(ATP):tRNA nucleotidyltransferase|transfer ribonucleate nucleotidyltransferase|transfer RNA adenylyltransferase|ATP(CTP):tRNA nucleotidyltransferase activity|ribonucleic cytidylic cytidylic adenylic pyrophosphorylase|ATP (CTP):tRNA nucleotidyltransferase|transfer ribonucleate cytidylyltransferase|ribonucleic cytidylyltransferase|transfer-RNA nucleotidyltransferase|tRNA CCA-pyrophosphorylase activity|tRNA CCA-diphosphorylase activity Catalysis of the reaction: CTP + tRNA(n) = diphosphate + tRNA(n+1). GO:0016438 tRNA-queuosine beta-mannosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016438 RHEA:12885|MetaCyc:2.4.1.110-RXN|EC:2.4.1.110 GDP-mannose:tRNAAsp-queuosine O-5''-beta-D-mannosyltransferase activity Catalysis of the reaction: GDP-mannose + tRNA(Asp)-queuosine = GDP + tRNA(Asp)-O-5''-beta-D-mannosylqueuosine. GO:0016439 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016439 GO:0016433 rRNA (adenine) methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016433 Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methyladenine. GO:0016434 rRNA (cytosine) methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016434 Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methylcytosine. GO:0016435 rRNA (guanine) methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016435 Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methylguanine. GO:0016436 rRNA (uridine) methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016436 Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methyluridine. GO:0016430 tRNA (adenine-N6-)-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016430 RHEA:16785|MetaCyc:TRNA-ADENINE-N6--METHYLTRANSFERASE-RXN|EC:2.1.1.55 S-adenosyl-L-methionine:tRNA (adenine-N6-)-methyltransferase activity|S-adenosyl-L-methionine:tRNA (adenine-6-N-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N6-methyladenine. GO:0016431 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016431 GO:0016432 tRNA-uridine aminocarboxypropyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016432 MetaCyc:2.5.1.25-RXN|EC:2.5.1.25|RHEA:12300 S-adenosyl-L-methionine:tRNA-uridine 3-(3-amino-3-carboxypropyl)transferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA uridine = 5'-methylthioadenosine + tRNA 3-(3-amino-3-carboxypropyl)-uridine. GO:0016408 C-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016408 Catalysis of the transfer of an acyl group to a carbon atom on the acceptor molecule. GO:0016409 palmitoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016409 Reactome:R-HSA-203567|Reactome:R-HSA-5686304 Catalysis of the transfer of a palmitoyl (CH3-[CH2]14-CO-) group to an acceptor molecule. GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016404 MetaCyc:1.1.1.141-RXN|Reactome:R-HSA-2161662|Reactome:R-HSA-9024766|EC:1.1.1.141|Reactome:R-HSA-9023968|RHEA:11876|Reactome:R-HSA-2161779 (5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-13-enoate:NAD+ 15-oxidoreductase activity|15-hydroxyprostanoic dehydrogenase activity|15-OH-PGDH|NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (type I)|15-hydroxyprostaglandin dehydrogenase activity|11alpha,15-dihydroxy-9-oxoprost-13-enoate:NAD+ 15-oxidoreductase activity|prostaglandin dehydrogenase activity|NAD-specific 15-hydroxyprostaglandin dehydrogenase activity Catalysis of the reaction: (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprost-13-enoate + NAD+ = (5Z,13E)-11-alpha-hydroxy-9,15-dioxoprost-13-enoate + NADH + H+. GO:0016405 CoA-ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016405 Reactome:R-HSA-159567|Reactome:R-HSA-159443|Reactome:R-HSA-6798345|Reactome:R-HSA-177157 Catalysis of the reaction: substrate + ATP + CoASH = AMP + diphosphate + substrate-CoA. GO:0016406 carnitine O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016406 Catalysis of the transfer of an acyl group to an oxygen atom on the carnitine molecule. GO:0016407 acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016407 Reactome:R-HSA-5682044|Reactome:R-HSA-6805638|Reactome:R-HSA-5628871|Reactome:R-HSA-5660660|Reactome:R-HSA-73736|Reactome:R-HSA-6792712 acetylase activity Catalysis of the transfer of an acetyl group to an acceptor molecule. GO:0016400 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016400 GO:0016401 palmitoyl-CoA oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016401 EC:1.3.3.- Catalysis of the reaction: palmitoyl-CoA + O2 = trans-2,3-dehydropalmitoyl-CoA + hydrogen peroxide. GO:0016402 pristanoyl-CoA oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016402 EC:1.3.3.-|Reactome:R-HSA-389891|RHEA:40459|Reactome:R-HSA-389889 Catalysis of the reaction: pristanoyl-CoA + O2 = trans-2,3-dehydropristanoyl-CoA + hydrogen peroxide. GO:0016403 dimethylargininase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016403 EC:3.5.3.18|RHEA:17305|Reactome:R-HSA-5693373|MetaCyc:DIMETHYLARGININASE-RXN NG,NG-dimethylarginine dimethylaminohydrolase activity|N(G),N(G)-dimethylarginine dimethylaminohydrolase activity|dimethylarginine dimethylaminohydrolase activity|NG,NG-dimethyl-L-arginine dimethylamidohydrolase activity Catalysis of the reaction: N(G),N(G)-dimethyl-L-arginine + H2O = dimethylamine + L-citrulline. CHEBI:65102 3-hydroxy fatty acyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65102 UBERON:0008906 lateral line nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008906 lateral line nerves Cranial nerves that carry afferent and efferent fibers for the lateral line system. UBERON:0008907 dermal bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008907 dermal bones Skeletal element that forms superficially in the organism, usually in association with the ectoderm[VSAO]. GO:0016419 S-malonyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016419 EC:2.3.1.39 Catalysis of the transfer of a malonyl group to a sulfur atom on the acceptor molecule. UBERON:0008909 perichordal bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008909 perichordal bones|perichordal bone Bone element that is adjacent to the notochord. CHEBI:546807 beta-D-Galp-(1->3)-D-GalpNAc biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_546807 CHEBI:546808 alpha-D-Gal-(1->4)-D-Gal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_546808 CHEBI:65100 trans,octacis-decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65100 CHEBI:65101 2-hydroxyhexadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65101 GO:0016415 octanoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016415 EC:2.3.1.181 Catalysis of the transfer of an octanoyl (CH3-[CH2]6-CO-) group to an acceptor molecule. GO:0016416 O-palmitoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016416 Reactome:R-HSA-2404137|Reactome:R-HSA-2453855|Reactome:R-HSA-2466710 Catalysis of the transfer of a palmitoyl group to an oxygen atom on the acceptor molecule. GO:0016417 S-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016417 Catalysis of the transfer of an acyl group to a sulfur atom on the acceptor molecule. GO:0016418 S-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016418 EC:2.3.1.38 Catalysis of the transfer of an acetyl group to a sulfur atom on the acceptor molecule. GO:0016411 acylglycerol O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016411 Reactome:R-HSA-1482654|Reactome:R-HSA-1482647 Catalysis of the transfer of an acyl group to an oxygen atom on the acylglycerol molecule. CHEBI:65106 1-monolysocardiolipin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65106 GO:0016412 serine O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016412 EC:2.3.1.30 Catalysis of the transfer of an acyl group to an oxygen atom on the serine molecule. UBERON:0008913 perichondral bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008913 perichondral bones|perichondral bone Bone element that is located on the surface of a cartilage element. CHEBI:65107 N-hexadecanoylphytosphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65107 GO:0016413 O-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016413 Catalysis of the transfer of an acetyl group to an oxygen atom on the acceptor molecule. CHEBI:65108 gamma-L-glutamylbutirosin B biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65108 GO:0016414 O-octanoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016414 Catalysis of the transfer of an octanoyl group to an oxygen atom on the acceptor molecule. CHEBI:65109 butirosin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65109 GO:0016410 N-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016410 Reactome:R-HSA-177160 Catalysis of the transfer of an acyl group to a nitrogen atom on the acceptor molecule. GO:1905370 serine-type endopeptidase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1905370 A protein complex which is capable of serine-type endopeptidase activity. GO:1905371 ceramide phosphoethanolamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905371 ceramide phosphoethanolamine metabolism The chemical reactions and pathways involving ceramide phosphoethanolamine. GO:1905372 ceramide phosphoethanolamine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905372 ceramide phosphoethanolamine degradation|ceramide phosphoethanolamine breakdown|ceramide phosphoethanolamine catabolism The chemical reactions and pathways resulting in the breakdown of ceramide phosphoethanolamine. GO:1905373 ceramide phosphoethanolamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905373 ceramide phosphoethanolamine anabolism|ceramide phosphoethanolamine biosynthesis|ceramide phosphoethanolamine synthesis|ceramide phosphoethanolamine formation The chemical reactions and pathways resulting in the formation of ceramide phosphoethanolamine. GO:1905374 response to homocysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905374 response to Hcy|response to 2-amino-4-mercaptobutyric acid|response to 2-amino-4-sulfanylbutanoic acid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a homocysteine stimulus. GO:1905375 cellular response to homocysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905375 cellular response to 2-amino-4-sulfanylbutanoic acid|cellular response to Hcy|cellular response to 2-amino-4-mercaptobutyric acid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a homocysteine stimulus. GO:1905376 negative regulation of cytochrome-c oxidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905376 negative regulation of cbb3-type cytochrome c oxidase|down-regulation of caa3-type cytochrome c oxidase|down-regulation of cbb3-type cytochrome c oxidase|negative regulation of caa3-type cytochrome c oxidase|down-regulation of NADH cytochrome c oxidase|inhibition of ferrocytochrome c oxidase|negative regulation of NADH cytochrome c oxidase|inhibition of cytochrome oxidase activity|inhibition of warburg's respiratory enzyme activity|down regulation of cytochrome aa3 activity|inhibition of ferrocytochrome-c:oxygen oxidoreductase|inhibition of ba3-type cytochrome c oxidase|negative regulation of complex IV (mitochondrial electron transport) activity|inhibition of aa3-type cytochrome c oxidase|down-regulation of complex IV (mitochondrial electron transport) activity|downregulation of cytochrome a3 activity|down regulation of cytochrome c oxidase activity|downregulation of cytochrome aa3 activity|down-regulation of cytochrome-c oxidase activity|inhibition of NADH cytochrome c oxidase|down regulation of ferrocytochrome c oxidase|negative regulation of indophenol oxidase|downregulation of caa3-type cytochrome c oxidase|down-regulation of indophenol oxidase|inhibition of indophenolase|downregulation of cbb3-type cytochrome c oxidase|down regulation of warburg's respiratory enzyme activity|down regulation of cytochrome oxidase activity|down regulation of ba3-type cytochrome c oxidase|down regulation of cytochrome a3 activity|down regulation of ferrocytochrome-c:oxygen oxidoreductase|downregulation of cytochrome c oxidase activity|downregulation of ferrocytochrome c oxidase|down regulation of aa3-type cytochrome c oxidase|down regulation of caa3-type cytochrome c oxidase|down regulation of cbb3-type cytochrome c oxidase|downregulation of warburg's respiratory enzyme activity|downregulation of complex IV (mitochondrial electron transport) activity|downregulation of cytochrome oxidase activity|downregulation of ferrocytochrome-c:oxygen oxidoreductase|inhibition of cytochrome-c oxidase activity|downregulation of ba3-type cytochrome c oxidase|downregulation of aa3-type cytochrome c oxidase|down regulation of indophenolase|down-regulation of cytochrome aa3 activity|negative regulation of cytochrome aa3 activity|down regulation of complex IV (mitochondrial electron transport) activity|inhibition of cytochrome a3 activity|downregulation of indophenol oxidase|inhibition of cbb3-type cytochrome c oxidase|downregulation of indophenolase|down regulation of NADH cytochrome c oxidase|inhibition of caa3-type cytochrome c oxidase|negative regulation of ferrocytochrome c oxidase|negative regulation of cytochrome c oxidase activity|down-regulation of cytochrome c oxidase activity|down-regulation of ferrocytochrome c oxidase|down regulation of indophenol oxidase|down-regulation of cytochrome oxidase activity|down-regulation of warburg's respiratory enzyme activity|negative regulation of cytochrome oxidase activity|negative regulation of warburg's respiratory enzyme activity|down-regulation of ba3-type cytochrome c oxidase|downregulation of NADH cytochrome c oxidase|down-regulation of ferrocytochrome-c:oxygen oxidoreductase|negative regulation of ba3-type cytochrome c oxidase|negative regulation of ferrocytochrome-c:oxygen oxidoreductase|down-regulation of aa3-type cytochrome c oxidase|negative regulation of aa3-type cytochrome c oxidase|inhibition of complex IV (mitochondrial electron transport) activity|down regulation of cytochrome-c oxidase activity|inhibition of cytochrome c oxidase activity|negative regulation of indophenolase|inhibition of cytochrome aa3 activity|inhibition of indophenol oxidase|down-regulation of indophenolase|down-regulation of cytochrome a3 activity|negative regulation of cytochrome a3 activity|downregulation of cytochrome-c oxidase activity Any process that stops, prevents or reduces the frequency, rate or extent of cytochrome-c oxidase activity. GO:1905377 response to D-galactose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905377 response to D-galacto-hexose|response to D-Gal Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactose stimulus. GO:1905367 positive regulation of intralumenal vesicle formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905367 up regulation of intralumenal vesicle formation|up-regulation of endosome membrane budding|upregulation of intralumenal vesicle formation|upregulation of endosome membrane budding|activation of intralumenal vesicle formation|up-regulation of intralumenal vesicle formation|up regulation of endosome membrane budding|activation of endosome membrane budding|positive regulation of endosome membrane budding Any process that activates or increases the frequency, rate or extent of intralumenal vesicle formation. GO:0090569 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090569 GO:1905368 peptidase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1905368 tryptase complex|protease complex A protein complex which is capable of peptidase activity. GO:0090567 reproductive shoot system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090567 The process whose specific outcome is the progression of a reproductive shoot system over time, from its formation to the mature structure. GO:1905369 endopeptidase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1905369 A protein complex which is capable of endopeptidase activity. GO:0090568 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090568 GO:0090561 nuclear migration during mitotic telophase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090561 The dynein-driven microtubule based nuclear migration, whereby daughter nuclei are positioned away from the cell division site prior to cytokinesis. GO:0090562 protein-N(PI)-phosphohistidine-N,N'-diacetylchitobiose phosphotransferase system transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090562 Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N,N'-diacetylchitobiose(out) = protein histidine + N,N'-diacetylchitobiose phosphate(in). GO:0090560 2-(3-amino-3-carboxypropyl)histidine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090560 RHEA:36783|Reactome:R-HSA-5358494|MetaCyc:RXN-11371 Catalysis of the reaction S-adenosyl-L-methionine + L-histidine-[translation elongation factor 2] = S-methyl-5-thioadenosine + 2-[(3S)-3-amino-3-carboxypropyl]-L-histidine-[translation elongation factor 2]. GO:0090565 protein-phosphocysteine-mannitol phosphotransferase system transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090565 Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + mannitol(out) = protein cysteine + mannitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. GO:0090566 protein-phosphocysteine-N,N'-diacetylchitobiose phosphotransferase system transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090566 Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + N,N'-diacetylchitobiose(out) = protein cysteine + N,N'-diacetylchitobiose phosphate(in). GO:0090563 protein-phosphocysteine-sugar phosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090563 Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + sugar(out) = protein cysteine + sugar phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. GO:0090564 protein-phosphocysteine-glucose phosphotransferase system transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090564 Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + glucose(out) = protein cysteine + glucose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. GO:1905380 regulation of snRNA transcription by RNA polymerase II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905380 regulation of snRNA transcription from RNA polymerase II promoter|regulation of snRNA transcription from Pol II promoter Any process that modulates the frequency, rate or extent of snRNA transcription mediated by RNA polymerase II. GO:1905381 negative regulation of snRNA transcription by RNA polymerase II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905381 negative regulation of snRNA transcription from RNA polymerase II promoter|down regulation of snRNA transcription from RNA polymerase II promoter|downregulation of snRNA transcription from RNA polymerase II promoter|negative regulation of snRNA transcription from Pol II promoter|down-regulation of snRNA transcription from Pol II promoter|down-regulation of snRNA transcription from RNA polymerase II promoter|downregulation of snRNA transcription from Pol II promoter|inhibition of snRNA transcription from RNA polymerase II promoter|down regulation of snRNA transcription from Pol II promoter|inhibition of snRNA transcription from Pol II promoter Any process that stops, prevents or reduces the frequency, rate or extent of snRNA transcription mediated by RNA polymerase II. GO:1905382 positive regulation of snRNA transcription by RNA polymerase II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905382 upregulation of snRNA transcription from RNA polymerase II promoter|activation of snRNA transcription from Pol II promoter|up-regulation of snRNA transcription from Pol II promoter|up regulation of snRNA transcription from RNA polymerase II promoter|activation of snRNA transcription from RNA polymerase II promoter|positive regulation of snRNA transcription from Pol II promoter|up regulation of snRNA transcription from Pol II promoter|up-regulation of snRNA transcription from RNA polymerase II promoter|upregulation of snRNA transcription from Pol II promoter|positive regulation of snRNA transcription from RNA polymerase II promoter Any process that activates or increases the frequency, rate or extent of snRNA transcription mediated by RNA polymerase II. GO:1905383 protein localization to presynapse biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905383 protein localisation to presynapse|recruitment of presynaptic proteins|protein localisation in presynapse|protein localization in presynapse A process in which a protein is transported to, or maintained in, a location within a presynapse. GO:1905384 regulation of protein localization to presynapse biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905384 regulation of protein localisation in presynapse|regulation of protein localization in presynapse|regulation of recruitment of presynaptic proteins|regulation of protein localisation to presynapse Any process that modulates the frequency, rate or extent of protein localization to presynapse. GO:1905385 negative regulation of protein localization to presynapse biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905385 inhibition of protein localisation to presynapse|downregulation of protein localization to presynapse|inhibition of recruitment of presynaptic proteins|down-regulation of protein localization in presynapse|negative regulation of protein localization in presynapse|downregulation of protein localisation in presynapse|down regulation of protein localization to presynapse|inhibition of protein localization to presynapse|down regulation of protein localisation in presynapse|inhibition of protein localisation in presynapse|downregulation of protein localization in presynapse|down regulation of recruitment of presynaptic proteins|down regulation of protein localization in presynapse|down-regulation of protein localisation to presynapse|downregulation of recruitment of presynaptic proteins|negative regulation of protein localisation to presynapse|inhibition of protein localization in presynapse|down-regulation of protein localization to presynapse|negative regulation of recruitment of presynaptic proteins|down-regulation of recruitment of presynaptic proteins|downregulation of protein localisation to presynapse|negative regulation of protein localisation in presynapse|down-regulation of protein localisation in presynapse|down regulation of protein localisation to presynapse Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to presynapse. GO:1905386 positive regulation of protein localization to presynapse biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905386 up regulation of protein localisation in presynapse|up-regulation of recruitment of presynaptic proteins|upregulation of protein localisation to presynapse|positive regulation of protein localization in presynapse|up regulation of protein localization in presynapse|upregulation of protein localization to presynapse|upregulation of recruitment of presynaptic proteins|up-regulation of protein localisation to presynapse|upregulation of protein localisation in presynapse|activation of protein localisation to presynapse|up-regulation of protein localization to presynapse|upregulation of protein localization in presynapse|activation of protein localization to presynapse|up regulation of recruitment of presynaptic proteins|up-regulation of protein localisation in presynapse|activation of protein localisation in presynapse|positive regulation of protein localisation to presynapse|activation of recruitment of presynaptic proteins|positive regulation of recruitment of presynaptic proteins|up regulation of protein localisation to presynapse|up-regulation of protein localization in presynapse|activation of protein localization in presynapse|up regulation of protein localization to presynapse|positive regulation of protein localisation in presynapse Any process that activates or increases the frequency, rate or extent of protein localization to presynapse. GO:1905387 response to beta-carotene biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905387 response to beta,beta-carotene Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a beta-carotene stimulus. GO:1905388 cellular response to beta-carotene biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905388 cellular response to beta,beta-carotene Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a beta-carotene stimulus. GO:1905378 cellular response to D-galactose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905378 cellular response to D-Gal|cellular response to D-galacto-hexose Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactose stimulus. GO:1905379 beta-N-acetylhexosaminidase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1905379 HEX B complex|HEX A complex|HEX S complex A protein complex which is capable of beta-N-acetylhexosaminidase activity. GO:0090578 RNA polymerase V transcription regulator complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090578 RNA polymerase V transcription factor complex A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase V. GO:0090579 dsDNA loop formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090579 dsDNA looping|chromatin looping The formation and maintenance of DNA loops that juxtapose separated regions on the same dsDNA molecule. GO:0090572 RNA polymerase III transcription repressor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090572 A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase III promoter. GO:0090573 RNA polymerase IV transcription repressor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090573 A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase IV promoter. GO:0090570 RNA polymerase I transcription repressor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090570 A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase I promoter. GO:0090571 RNA polymerase II transcription repressor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090571 A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase II promoter. GO:0090576 RNA polymerase III transcription regulator complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090576 RNA polymerase III transcription factor complex A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase III. GO:0090577 RNA polymerase IV transcription regulator complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090577 RNA polymerase IV transcription factor complex A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase IV. GO:0090574 RNA polymerase V transcription repressor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090574 A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase V promoter. GO:0090575 RNA polymerase II transcription regulator complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090575 RNA polymerase II transcription factor complex A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase II. GO:1905390 cellular response to leukotriene B4 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905390 cellular response to LTB4 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukotriene B4 stimulus. GO:1905391 regulation of protein localization to cell division site involved in cell separation after cytokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905391 regulation of protein localisation to cell division site involved in cell separation following cytokinesis|regulation of protein localisation to cell division site involved in cytokinetic cell separation|regulation of protein localisation to cell division site involved in mitotic cytokinetic cell separation|regulation of protein localisation to cell division site involved in cell separation after cytokinesis Any regulation of protein localization to cell division site that is involved in cell separation after cytokinesis. GO:1905392 plant organ morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905392 The developmental process by which a plant organ is generated and organized. GO:1905393 plant organ formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905393 The process that gives rise to the plant organ. This process pertains to the initial formation of a structure from unspecified parts. GO:1905394 retromer complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1905394 Interacting selectively and non-covalently with a retromer complex. GO:1905395 response to flavonoid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905395 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a flavonoid stimulus. GO:1905396 cellular response to flavonoid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905396 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a flavonoid stimulus. GO:1905397 activated CD8-positive, alpha-beta T cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905397 activated CD8-positive, alpha-beta T-cell apoptosis|activated CD8-positive, alpha-beta T-lymphocyte apoptosis|activated CD8-positive, alpha-beta T-cell apoptotic process|activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|activated CD8-positive, alpha-beta T cell apoptosis|activated CD8-positive, alpha-beta T lymphocyte apoptosis|activated CD8-positive, alpha-beta T lymphocyte apoptotic process Any apoptotic process in an activated CD8-positive, alpha-beta T cell. GO:1905398 activated CD4-positive, alpha-beta T cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905398 activated CD4-positive, alpha-beta T-cell apoptosis|activated CD4-positive, alpha-beta T-lymphocyte apoptosis|activated CD4-positive, alpha-beta T-cell apoptotic process|activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|activated CD4-positive, alpha-beta T cell apoptosis|activated CD4-positive, alpha-beta T lymphocyte apoptosis|activated CD4-positive, alpha-beta T lymphocyte apoptotic process Any apoptotic process in an activated CD4-positive, alpha-beta T cell. GO:1905399 regulation of activated CD4-positive, alpha-beta T cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905399 regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|regulation of activated CD4-positive, alpha-beta T-cell apoptotic process|regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|regulation of activated CD4-positive, alpha-beta T cell apoptosis|regulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|regulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|regulation of activated CD4-positive, alpha-beta T-cell apoptosis Any process that modulates the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process. GO:0090547 response to low humidity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090547 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of low humidity stimulus, reduced moisture in the atmosphere. GO:1905389 response to leukotriene B4 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905389 response to LTB4 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukotriene B4 stimulus. GO:0090548 response to nitrate starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090548 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nitrate. GO:0090545 CHD-type complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090545 A SWI/SNF-type complex that contains a subunit from the CHD(Chromodomain helicase DNA-binding) family. The CHD family is characterized by two signature sequence motifs: tandem chromodomains located in the N-terminal region, and the SNF2-like ATPase domain located in the central region of the protein structure. GO:0090546 chlorophyll fluorescence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090546 The process by which excess light energy absorbed by chlorophyll and not used to drive photosynthesis is re-emitted as light. GO:0090549 response to carbon starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090549 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of a carbon source. GO:0090540 bacterial cellulose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090540 bacterial cellulose biosynthesis The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, as it occurs in certain types of bacteria, mainly Acetobacter, Sarcina ventriculi and Agrobacteria. GO:0090543 Flemming body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090543 Midbody ring A cell part that is the central region of the midbody characterized by a gap in alpha-tubulin staining. It is a dense structure of antiparallel microtubules from the central spindle in the middle of the intercellular bridge. GO:0090544 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090544 GO:0090541 MIT domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090541 Interacting selectively and non-covalently with the MIT domain of a protein. The MIT domain is found in vacuolar sorting proteins, spastin (probable ATPase involved in the assembly or function of nuclear protein complexes), and a sorting nexin, which may play a role in intracellular trafficking. GO:0090542 ELYC domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090542 Interacting selectively and non-covalently with the ELYC domain of a protein. The ELYC domain is an approximately 150 amino acid sequence which contains a highly conserved tetrapeptide sequence, ELYC. GO:0090558 plant epidermis development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090558 The process whose specific outcome is the progression of the plant epidermis over time, from its formation to the mature structure. GO:0090559 regulation of membrane permeability biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090559 Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by a membrane. GO:0090556 phosphatidylserine floppase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090556 RHEA:38568 ATPase-dependent phosphatidylserine transporter activity|phosphatidylserine floppase activity (cytosolic to exoplasmic leaftlet)|phosphatidylserine-translocating ATPase activity|ATPase-coupled phosphatidylserine transporter activity Catalysis of the movement of phosphatidylserine from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP. GO:0090557 establishment of endothelial intestinal barrier biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090557 The establishment of a barrier between endothelial cell layers of the intestine to exert specific and selective control over the passage of water and solutes, thus allowing formation and maintenance of compartments that differ in fluid and solute composition. GO:0090550 response to molybdenum starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090550 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of molybdenum. GO:0090551 response to manganese starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090551 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of manganese. GO:0090554 phosphatidylcholine floppase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090554 RHEA:38584 phosphatidylcholine-translocating ATPase activity|ATPase-coupled phosphatidylcholine transporter activity|ATP-dependent phosphatidylcholine transporter activity|phosphatidylcholine floppase activity (cytosolic to exoplasmic leaftlet) Catalysis of the movement of phosphatidylcholine from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP. GO:0090555 phosphatidylethanolamine flippase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090555 RHEA:36440 ATP-dependent phosphatidylethanolamine transporter activity|ATPase-coupled phosphatidylethanolamine transporter activity|phosphatidylethanolamine flippase activity (exoplasmic to cytosolic leaftlet)|phosphatidylethanolamine-translocating ATPase activity Catalysis of the movement of phosphatidylethanolamine from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP. GO:0090552 unicellular trichome apex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090552 A cell projection part that is the apical most portion of a unicellular trichome. GO:0090553 unicellular trichome tip biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090553 A cell projection part that is the apical most portion of a unicellular trichome apex. CHEBI:5130 flurbiprofen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_5130 GO:0090580 phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090580 Catalysis of the hydrolytic removal of phosphoglycolate from the 3'-terminus of a 3'-phosphoglycolate-terminated DNA strand. GO:0090589 protein-phosphocysteine-trehalose phosphotransferase system transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090589 Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + trehalose (out) = protein cysteine + trehalose-6-phosphate (in). GO:0090583 protein-phosphocysteine-D-sorbitol-phosphotransferase system transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090583 Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + D-sorbitol(out) = protein cysteine + D-sorbitol-1-phosphate(in). GO:0090584 protein-phosphocysteine-galactitol-phosphotransferase system transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090584 Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + galactitol(out) = protein cysteine + galactitol-6-phosphate(in). GO:0090581 protein-phosphocysteine-mannosylglycerate-phosphotransferase system transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090581 Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + mannosylglycerate(out) = protein cysteine + mannosylglycerate phosphate(in). GO:0090582 protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090582 Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + D-fructose(out) = protein cysteine + D-fructose-1-phosphate(in). GO:0090587 protein-phosphocysteine-glucosamine phosphotransferase system transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090587 Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + glucosamine (out) = protein cysteine + glucosamine-6-phosphate (in). GO:0090588 protein-phosphocysteine-N-acetylmuramate phosphotransferase system transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090588 Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + N-acetylmuramate (out) = protein cysteine + N-acetylmuramate-6-phosphate (in). GO:0090585 protein-phosphocysteine-L-ascorbate-phosphotransferase system transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090585 Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + L-ascorbate(out) = protein cysteine + L-ascorbate-6-phosphate(in). GO:0090586 protein-phosphocysteine-N-acetylglucosamine phosphotransferase system transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090586 Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + N-acetylglucosamine (out) = protein cysteine + N-acetylglucosamine-6-phosphate (in). CHEBI:149778 methyl-L-glutamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_149778 CHEBI:149779 Mannogen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_149779 GO:0090590 protein-N(PI)-phosphohistidine-D-glucosamine phosphotransferase system transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090590 Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + D-glucosamine(out) = protein histidine + glucosamine-6-phosphate(in). GO:0090591 protein-N(PI)-phosphohistidine-N-acetyl-mannosamine phosphotransferase system transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090591 Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N-acetyl-mannosamine(out) = protein histidine +N-acetyl- mannosamine-6-phosphate(in). CHEBI:5118 fluoxetine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_5118 CHEBI:5115 monofluorobenzene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_5115 GO:0090594 inflammatory response to wounding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090594 The immediate defensive reaction by vertebrate tissue to injury caused by chemical or physical agents. GO:0090595 acetyl-CoA:L-lysine N6-acetyltransferase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090595 Catalysis of the reaction: L-lysine + acetyl-CoA = N6-acetyl-L-lysine + CoA + H(+). GO:0090592 DNA synthesis involved in DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090592 Synthesis of DNA that is a part of the process of duplicating one or more molecules of DNA. GO:0090593 peptidyl-histidine autophosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090593 The phosphorylation by a protein of one or more of its own histidine residues, or a histidine residue on an identical protein. GO:0090598 male anatomical structure morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090598 The processes by which anatomical structures that are only present in the male organism are generated and organized. GO:0090599 alpha-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090599 Reactome:R-HSA-9036729|Reactome:R-HSA-9036727|EC:3.2.1.20 Catalysis of the hydrolysis of terminal, non-reducing alpha-linked alpha-D-glucose residue with release of alpha-D-glucose. GO:0090596 sensory organ morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090596 Morphogenesis of a sensory organ. A sensory organ is defined as a tissue or set of tissues that work together to receive and transmit signals from external or internal stimuli. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. GO:0090597 nematode male tail mating organ morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090597 The process in which the anatomical structures of the nematode male tail mating organ are generated and organized. The male tail is a sensory organ required for mating and, in C. elegans, consists of ray sensilla, an acellular cuticular fan, a sensory hook, and protracting, copulatory spicules. CHEBI:65072 carboxyspermidine(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65072 CHEBI:65073 C20 3-dehydrosphinganine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65073 CHEBI:65074 N-hexacosanoyl-C20-4-hydroxysphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65074 CHEBI:65075 2'-deamino-2'-hydroxyparomamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65075 CHEBI:5171 friedelin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_5171 CHEBI:65070 carboxynorspermidine(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65070 CHEBI:65071 2'-deamino-2'-hydroxyparomamine(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65071 CHEBI:65076 neamine(4+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65076 CHEBI:65077 neomycin C(6+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65077 CHEBI:65078 isopentenyl phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65078 CHEBI:65079 trans,polycis-decaprenyl phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65079 CHEBI:65084 2-hydroxyoctadecanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65084 CHEBI:65085 butirosin B(4+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65085 CHEBI:65086 gamma-L-glutamylbutirosin B(3+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65086 CHEBI:65080 N-acetyl-alpha-D-glucosaminyl-1-diphospho-trans,polycis-decaprenol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65080 CHEBI:65081 2-oxo-3-(5-oxofuran-2-ylidene)propanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65081 CHEBI:65082 5''-phosphoribostamycin(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65082 CHEBI:31746 kainic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31746 CHEBI:65087 (9Z)-myristoleoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65087 CHEBI:65088 docosanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65088 CHEBI:31748 3-amino-3-deoxy-6-O-phosphono-D-glucopyranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31748 CHEBI:65089 Ins-1-P-Cer(d18:0/26:0)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65089 GO:1905300 positive regulation of intestinal epithelial cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905300 up regulation of intestinal epithelial cell development|upregulation of intestinal epithelial cell development|up-regulation of intestinal epithelial cell development|activation of intestinal epithelial cell development Any process that activates or increases the frequency, rate or extent of intestinal epithelial cell development. CHEBI:90029 PS(16:0/20:4(5Z,8Z,11Z,14Z)) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90029 CHEBI:31742 kaempferol 3-O-beta-D-galactoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31742 CHEBI:65094 Ins-1-P-Cer(d18:0/2-OH-26:0)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65094 CHEBI:65096 trans,octacis-decaprenylphospho-beta-D-arabinofuranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65096 CHEBI:65097 2-hydroxyhexadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65097 CHEBI:65090 1-octadecanoyl-2-acyl-sn-glycero-3-phospho-1D-myo-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65090 CHEBI:65091 Ins-1-P-Cer(d18:0/24:0)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65091 CHEBI:65092 1-monolysocardiolipin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65092 CHEBI:65098 6'''-oxoneomycin C biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65098 GO:1905310 regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905310 Any process that modulates the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis. GO:1905311 negative regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905311 downregulation of cardiac neural crest cell migration involved in outflow tract morphogenesis|down-regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis|inhibition of cardiac neural crest cell migration involved in outflow tract morphogenesis|down regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis. GO:1905301 regulation of macropinocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905301 regulation of clathrin-independent pinocytosis Any process that modulates the frequency, rate or extent of macropinocytosis. GO:1905302 negative regulation of macropinocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905302 down-regulation of macropinocytosis|downregulation of macropinocytosis|down regulation of macropinocytosis|inhibition of macropinocytosis Any process that stops, prevents or reduces the frequency, rate or extent of macropinocytosis. CHEBI:16119 shikimic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16119 GO:1905303 positive regulation of macropinocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905303 up regulation of macropinocytosis|upregulation of macropinocytosis|up-regulation of macropinocytosis|activation of macropinocytosis Any process that activates or increases the frequency, rate or extent of macropinocytosis. GO:1905304 regulation of cardiac myofibril assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905304 regulation of cardiac myofibril morphogenesis|regulation of cardiac myofibril development|regulation of heart myofibril assembly Any process that modulates the frequency, rate or extent of cardiac myofibril assembly. GO:1905305 negative regulation of cardiac myofibril assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905305 down regulation of cardiac myofibril morphogenesis|down regulation of cardiac myofibril assembly|inhibition of cardiac myofibril assembly|negative regulation of heart myofibril assembly|downregulation of cardiac myofibril morphogenesis|down-regulation of heart myofibril assembly|down regulation of cardiac myofibril development|downregulation of cardiac myofibril development|negative regulation of cardiac myofibril morphogenesis|downregulation of heart myofibril assembly|down-regulation of cardiac myofibril morphogenesis|down regulation of heart myofibril assembly|down-regulation of cardiac myofibril development|negative regulation of cardiac myofibril development|down-regulation of cardiac myofibril assembly|inhibition of cardiac myofibril morphogenesis|inhibition of heart myofibril assembly|inhibition of cardiac myofibril development|downregulation of cardiac myofibril assembly Any process that stops, prevents or reduces the frequency, rate or extent of cardiac myofibril assembly. GO:1905306 positive regulation of cardiac myofibril assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905306 upregulation of cardiac myofibril morphogenesis|activation of heart myofibril assembly|upregulation of cardiac myofibril development|upregulation of cardiac myofibril assembly|up regulation of cardiac myofibril morphogenesis|positive regulation of heart myofibril assembly|activation of cardiac myofibril morphogenesis|up regulation of heart myofibril assembly|positive regulation of cardiac myofibril morphogenesis|activation of cardiac myofibril assembly|up regulation of cardiac myofibril development|up-regulation of cardiac myofibril assembly|activation of cardiac myofibril development|positive regulation of cardiac myofibril development|upregulation of heart myofibril assembly|up-regulation of cardiac myofibril morphogenesis|up regulation of cardiac myofibril assembly|up-regulation of cardiac myofibril development|up-regulation of heart myofibril assembly Any process that activates or increases the frequency, rate or extent of cardiac myofibril assembly. CHEBI:16118 berberine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16118 GO:1905307 response to miconazole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905307 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a miconazole stimulus. GO:1905308 cellular response to miconazole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905308 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a miconazole stimulus. CHEBI:16116 3-hydroxy-4-methylanthranilic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16116 GO:1905309 positive regulation of cohesin loading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905309 positive regulation of cohesin localization to chromatin|positive regulation of cohesin association with chromatin Any process that activates or increases the frequency, rate or extent of cohesin loading. CHEBI:16113 cholesterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16113 CHEBI:16114 medicarpin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16114 CHEBI:16111 nonane-4,6-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16111 CHEBI:16112 chlorogenic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16112 CHEBI:16110 1,2-diacyl-sn-glycero-3-phosphocholine(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16110 GO:1905320 regulation of mesenchymal stem cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905320 Any process that modulates the frequency, rate or extent of mesenchymal stem cell migration. GO:1905321 negative regulation of mesenchymal stem cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905321 down regulation of mesenchymal stem cell migration|downregulation of mesenchymal stem cell migration|down-regulation of mesenchymal stem cell migration|inhibition of mesenchymal stem cell migration Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell migration. GO:1905322 positive regulation of mesenchymal stem cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905322 upregulation of mesenchymal stem cell migration|up regulation of mesenchymal stem cell migration|activation of mesenchymal stem cell migration|up-regulation of mesenchymal stem cell migration Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell migration. GO:1905312 positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905312 up regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis|activation of cardiac neural crest cell migration involved in outflow tract morphogenesis|up-regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis|upregulation of cardiac neural crest cell migration involved in outflow tract morphogenesis Any process that activates or increases the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis. GO:1905313 transforming growth factor beta receptor signaling pathway involved in heart development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905313 TGF-beta receptor signalling pathway involved in dorsal vessel development|TGF-beta receptor signaling pathway involved in dorsal vessel development|TGFbeta receptor signalling pathway involved in heart development|transforming growth factor beta receptor signalling pathway involved in cardiac development|TGFbeta receptor signalling pathway involved in dorsal vessel development|TGFbeta receptor signaling pathway involved in cardiac development|transforming growth factor beta receptor signaling pathway involved in dorsal vessel development|TGF-beta receptor signaling pathway involved in cardiac development|TGF-beta receptor signalling pathway involved in cardiac development|TGFbeta receptor signalling pathway involved in cardiac development|transforming growth factor beta receptor signaling pathway involved in cardiac development|transforming growth factor beta receptor signalling pathway involved in heart development|TGFbeta receptor signaling pathway involved in heart development|transforming growth factor beta receptor signalling pathway involved in dorsal vessel development|TGFbeta receptor signaling pathway involved in dorsal vessel development|TGF-beta receptor signaling pathway involved in heart development|TGF-beta receptor signalling pathway involved in heart development Any transforming growth factor beta receptor signaling pathway that is involved in heart development. GO:1905314 semi-lunar valve development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905314 semilunar valve development|semilunar valves development The process whose specific outcome is the progression of a semi-lunar valve over time, from its formation to the mature structure. CHEBI:16108 dihydroxyacetone phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16108 CHEBI:16109 propane-1,3-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16109 GO:1905315 cell proliferation involved in endocardial cushion morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905315 Any cell proliferation that is involved in endocardial cushion morphogenesis. GO:1905316 superior endocardial cushion morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905316 dorsal endocardial cushion morphogenesis The developmental process by which a superior endocardial cushion is generated and organized. CHEBI:16106 2,4-dichloro-5-oxo-2,5-dihydro-2-furylacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16106 GO:1905317 inferior endocardial cushion morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905317 ventral endocardial cushion morphogenesis The developmental process by which an inferior endocardial cushion is generated and organized. GO:1905318 meiosis I spindle assembly checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905318 Any spindle assembly checkpoint that is involved in meiosis I. CHEBI:16104 3-(2-hydroxyphenyl)propanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16104 GO:1905319 mesenchymal stem cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905319 The orderly movement of a mesenchymal stem cell from one site to another. CHEBI:16100 1,6-dihydroxy-2-methylcyclohexa-2,4-dienecarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16100 CHEBI:16101 ethylbenzene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16101 GO:1905330 regulation of morphogenesis of an epithelium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905330 regulation of epithelium morphogenesis Any process that modulates the frequency, rate or extent of morphogenesis of an epithelium. GO:1905331 negative regulation of morphogenesis of an epithelium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905331 down-regulation of morphogenesis of an epithelium|negative regulation of epithelium morphogenesis|down-regulation of epithelium morphogenesis|downregulation of morphogenesis of an epithelium|down regulation of morphogenesis of an epithelium|inhibition of morphogenesis of an epithelium|downregulation of epithelium morphogenesis|down regulation of epithelium morphogenesis|inhibition of epithelium morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of morphogenesis of an epithelium. GO:1905332 positive regulation of morphogenesis of an epithelium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905332 up-regulation of epithelium morphogenesis|activation of epithelium morphogenesis|up regulation of morphogenesis of an epithelium|positive regulation of epithelium morphogenesis|up regulation of epithelium morphogenesis|upregulation of morphogenesis of an epithelium|upregulation of epithelium morphogenesis|up-regulation of morphogenesis of an epithelium|activation of morphogenesis of an epithelium Any process that activates or increases the frequency, rate or extent of morphogenesis of an epithelium. GO:1905333 regulation of gastric motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905333 Any process that modulates the frequency, rate or extent of gastric motility. GO:1905323 telomerase holoenzyme complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905323 telomerase holoenzyme complex formation The aggregation, arrangement and bonding together of a set of components to form a telomerase holoenzyme complex. GO:0090525 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090525 GO:1905324 telomere-telomerase complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905324 telomere-telomerase complex formation The aggregation, arrangement and bonding together of a set of components to form a telomere-telomerase complex. GO:0090526 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090526 GO:1905325 regulation of meiosis I spindle assembly checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905325 Any process that modulates the frequency, rate or extent of the meiosis I spindle assembly checkpoint. GO:0090523 cytochrome-b5 reductase activity, acting on NADPH biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090523 cytochrome-b5 reductase activity Catalysis of the reaction: NADPH + H+ + 2 ferricytochrome b(5) = NADP+ + 2 ferrocytochrome b(5). GO:0090524 cytochrome-b5 reductase activity, acting on NADH biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090524 cytochrome b5 reductase activity Catalysis of the reaction: NADH + H+ + 2 ferricytochrome b(5) = NAD+ + 2 ferrocytochrome b(5). GO:1905326 positive regulation of meiosis I spindle assembly checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905326 up-regulation of meiosis I spindle assembly checkpoint|upregulation of meiosis I spindle assembly checkpoint|up regulation of meiosis I spindle assembly checkpoint|activation of meiosis I spindle assembly checkpoint Any process that activates or increases the frequency, rate or extent of the meiosis I spindle assembly checkpoint. GO:0090529 cell septum assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090529 cell septum assembly involved in cell cycle cytokinesis The assembly and arrangement of a cellular component that is composed of peptidoglycan and often chitin in addition to other materials and usually forms perpendicular to the long axis of a cell or hypha. It grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells. GO:1905327 tracheoesophageal septum formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905327 tracheoesophageal ridges formation|esophagotracheal septum formation The process that gives rise to the tracheoesophageal septum. This process pertains to the initial formation of a structure from unspecified parts. GO:1905328 plant septum development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905328 dissepiment development The process whose specific outcome is the progression of a septum over time, from its formation to the mature structure. GO:1905329 sphingoid long-chain base transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905329 sphingosine transport|sphingoid base(1+) transport|dihydrosphingosine transport|long-chain base transport|sphingoid transport|phytosphingosine transport The directed movement of a sphingoid long-chain base, sometimes referred to as long-chain base, or sphingoid base, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sphingoid long-chain bases are long-chain aliphatic amines that are the fundamental building blocks of sphingolipids. The main mammalian sphingoid long-chain bases are dihydrosphingosine and sphingosine, while dihydrosphingosine and phytosphingosine are the main sphingoid long-chain bases in yeast. GO:0090527 actin filament reorganization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090527 A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of actin filaments. GO:0090528 smooth septate junction assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090528 The assembly of a smooth septate junction, a septate junction that lacks the regular arrays of electron-dense septae found in pleated septate junctions. GO:0090521 glomerular visceral epithelial cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090521 podocyte cell migration The orderly movement of a podocyte from one site to another, often during the development of a multicellular organism or multicellular structure. A podocyte is a specialized kidney epithelial cell. CHEBI:90076 (8Z,11Z,14Z)-icosatrienoyl-containing glycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90076 GO:0090522 vesicle tethering involved in exocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090522 vesicle tethering to plasma membrane The initial, indirect interaction between a secretory vesicle membrane and a site of exocytosis in the plasma membrane. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to docking and fusion. CHEBI:90077 arachidonoyl-containing glycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90077 CHEBI:90078 alpha-linolenoyl-containing glycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90078 GO:0090520 sphingolipid mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090520 sphingolipid signaling pathway|ceramide 1-phosphate signaling pathway|ceramide signaling pathway|sphingolipid mediated signal transduction|sphingolipid-mediated signaling pathway|sphingosine signaling pathway A series of molecular signals mediated by a sphingolipid. CHEBI:90079 (6Z,9Z,12Z,15Z)-octadecatetraenoyl-containing glycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90079 GO:1905340 regulation of protein localization to kinetochore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905340 regulation of protein localisation to kinetochore|regulation of condensin localization to kinetochore Any process that modulates the frequency, rate or extent of protein localization to kinetochore. GO:1905341 negative regulation of protein localization to kinetochore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905341 downregulation of protein localization to kinetochore|down regulation of protein localisation to kinetochore|inhibition of condensin localization to kinetochore|downregulation of protein localisation to kinetochore|down-regulation of protein localization to kinetochore|down regulation of condensin localization to kinetochore|inhibition of protein localization to kinetochore|down-regulation of protein localisation to kinetochore|downregulation of condensin localization to kinetochore|negative regulation of protein localisation to kinetochore|inhibition of protein localisation to kinetochore|negative regulation of condensin localization to kinetochore|down-regulation of condensin localization to kinetochore|down regulation of protein localization to kinetochore Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to kinetochore. GO:1905342 positive regulation of protein localization to kinetochore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905342 upregulation of protein localisation to kinetochore|up-regulation of condensin localization to kinetochore|up regulation of protein localization to kinetochore|activation of protein localization to kinetochore|upregulation of condensin localization to kinetochore|up regulation of protein localisation to kinetochore|positive regulation of protein localisation to kinetochore|activation of protein localisation to kinetochore|up-regulation of protein localization to kinetochore|up regulation of condensin localization to kinetochore|positive regulation of condensin localization to kinetochore|up-regulation of protein localisation to kinetochore|upregulation of protein localization to kinetochore|activation of condensin localization to kinetochore Any process that activates or increases the frequency, rate or extent of protein localization to kinetochore. GO:1905343 regulation of cohesin unloading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905343 Any process that modulates the frequency, rate or extent of cohesin unloading. GO:1905344 prostaglandin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905344 prostaglandin catabolism|prostaglandin degradation|prostaglandin breakdown The chemical reactions and pathways resulting in the breakdown of prostaglandin. GO:0090536 NoRC complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090536 An ISWI complex that contains an ATPase subunit of the ISWI family (specifically SNF2H in mammals, which contain two ISWI homologs) and a Tip5 homolog. In mammals, NoRC is involved in regulation of transcription from RNAP I and RNA polymerase III promoters. GO:1905334 Swi5-Sfr1 complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1905334 Sae3-Mei5 complex binding Interacting selectively and non-covalently with a Swi5-Sfr1 complex. GO:0090537 CERF complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090537 An ISWI complex that contains an ATPase subunit of the ISWI family (specifically SNF2L in mammals, which contain two ISWI homologs) and a CECR2 homolog. In mammals, CERF is involved in regulation of transcription from RNA polymerase II promoters. GO:1905335 regulation of aggrephagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905335 Any process that modulates the frequency, rate or extent of aggrephagy. GO:1905336 negative regulation of aggrephagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905336 down-regulation of aggrephagy|downregulation of aggrephagy|down regulation of aggrephagy|inhibition of aggrephagy Any process that stops, prevents or reduces the frequency, rate or extent of aggrephagy. GO:0090534 calcium ion-transporting ATPase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090534 Protein complex that carries out the reaction: ATP + H2O + Ca2+(out) = ADP + phosphate + Ca2+(in). GO:0090535 WICH complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090535 An ISWI complex that contains an ATPase subunit of the ISWI family (specifically SNF2H in mammals, which contain two ISWI homologs) and WSTF (Williams Syndrome Transcription Factor). WICH plays roles in regulation of RNAP I and III transcription and in DNA replication and repair. GO:1905337 positive regulation of aggrephagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905337 up-regulation of aggrephagy|activation of aggrephagy|up regulation of aggrephagy|upregulation of aggrephagy Any process that activates or increases the frequency, rate or extent of aggrephagy. GO:1905338 negative regulation of cohesin unloading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905338 inhibition of cohesin unloading|down regulation of cohesin unloading|downregulation of cohesin unloading|down-regulation of cohesin unloading Any process that stops, prevents or reduces the frequency, rate or extent of cohesin unloading. GO:1905339 positive regulation of cohesin unloading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905339 up-regulation of cohesin unloading|upregulation of cohesin unloading|up regulation of cohesin unloading|activation of cohesin unloading Any process that activates or increases the frequency, rate or extent of cohesin unloading. GO:0090538 peptide pheromone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090538 The regulated release of a peptide pheromone from a cell. GO:0090539 peptide pheromone export by transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090539 peptide pheromone export by membrane transport The directed movement of a peptide pheromone across a membrane and out of a cell. GO:0090532 L-ascorbic acid biosynthetic process via UDP-alpha-D-glucuronate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090532 L-ascorbic acid biosynthesis via UDP-alpha-D-glucuronate The chemical reactions and pathways resulting in the formation of L-ascorbic acid via the intermediate UDP-alpha-D-glucuronate. GO:0090533 cation-transporting ATPase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090533 Protein complex that carries out the reaction: ATP + H2O + cation(out) = ADP + phosphate + cation(in). GO:0090530 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090530 GO:0090531 L-ascorbic acid biosynthetic process via GDP-alpha-D-mannose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090531 BioCyc:PWY-882 L-ascorbic acid biosynthesis via GDP-alpha-D-mannose|Smirnoff-Wheeler's pathway The chemical reactions and pathways resulting in the formation of L-ascorbic acid via the intermediate GDP-alpha-D-mannose. CHEBI:90095 2-dehydro-3,6-dideoxy-6-sulfo-D-gluconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90095 CHEBI:90092 alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-L-Fuc-(1->4)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90092 CHEBI:90093 alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-L-Fuc-(1->4)]-[alpha-Neu5Ac-(2->6)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90093 GO:1905350 Y-shaped link assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905350 Y-shaped assemblage formation|Y-link structure assembly|Y-shaped fiber assembly|Y-shaped linker formation|membrane-microtubule complex assembly|Y-link formation|Y-shaped fibre assembly|Y-shaped fibre formation|Y-shaped link formation|membrane-microtubule complex formation|Y-link assembly|Y-shaped linker assembly|Y-shaped fiber formation|Y-link structure formation|Y-shaped assemblage assembly The aggregation, arrangement and bonding together of a set of components to form a Y-shaped link. Two distinct protein complexes are known to be involved in proper linker assembly: the MKS complex and the NPHP complex. Improper assembly of Y-shaped links may cause malfunctioning of the transition zone as a molecular gate. GO:1905351 pericyte cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905351 The orderly movement of a pericyte cell from one site to another. GO:1905352 ciliary necklace assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905352 cilium necklace assembly|ciliary necklace formation|cilial necklace assembly|cilial necklace formation|cilium necklace formation The aggregation, arrangement and bonding together of a set of components to form a ciliary necklace. GO:1905353 ciliary transition fiber assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905353 cilial transition fibre formation|cilial transition fiber formation|ciliary transition fibre assembly|cilium transition fiber assembly|distal appendage of basal body assembly|cilium transition fibre formation|cilium transition fibre assembly|centriolar distal appendage assembly|cilium transition fiber formation|distal appendage of mother centriole formation|distal appendage of centriole assembly|distal appendage of centriole formation|distal appendage of mother centriole assembly|centriolar distal appendage formation|ciliary transition fibre formation|cilial transition fiber assembly|distal appendage of basal body formation|cilial transition fibre assembly|ciliary transition fiber formation The aggregation, arrangement and bonding together of a set of components to form a ciliary transition fiber. GO:1905354 exoribonuclease complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1905354 A protein complex which is capable of exoribonuclease activity. GO:1905355 spine apparatus assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905355 dense material assembly|dense material formation|spine apparatus formation The aggregation, arrangement and bonding together of a set of components to form a spine apparatus. GO:1905345 protein localization to cleavage furrow biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905345 protein localization in cleavage furrow|protein localisation in cleavage furrow|protein localisation to cleavage furrow A process in which a protein is transported to, or maintained in, a location within a cleavage furrow. GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090503 The chemical reactions and pathways involving the hydrolysis of terminal 3',5'-phosphodiester bonds in one or two strands of ribonucleotides. GO:1905346 protein localization to cleavage furrow rim biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905346 protein localisation to cleavage furrow rim|protein localization in cleavage furrow rim|protein localisation in cleavage furrow rim A process in which a protein is transported to, or maintained in, a location within a cleavage furrow rim. GO:0090504 epiboly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090504 The expansion of one cell sheet over other cells or yolk. GO:1905347 endodeoxyribonuclease complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1905347 Mus81-Eme2 complex|Mus81-Eme1 complex A protein complex which is capable of endodeoxyribonuclease activity. GO:0090501 RNA phosphodiester bond hydrolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090501 The RNA metabolic process in which the phosphodiester bonds between ribonucleotides are cleaved by hydrolysis. GO:1905348 endonuclease complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1905348 A protein complex which is capable of endonuclease activity. GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090502 The chemical reactions and pathways involving the hydrolysis of internal 3',5'-phosphodiester bonds in one or two strands of ribonucleotides. GO:1905349 ciliary transition zone assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905349 cilial transition zone formation|cilium transition zone assembly|ciliary transition zone formation|cilium transition zone formation|cilial transition zone assembly The aggregation, arrangement and bonding together of a set of components to form a ciliary transition zone. GO:0090507 phenylethylamine metabolic process involved in synaptic transmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090507 The chemical reactions and pathways involving phenylethylamine that contribute to synaptic transmission. GO:0090508 phenylethylamine biosynthetic process involved in synaptic transmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090508 The chemical reactions and pathways resulting in the formation of phenylethylamine that contribute to synaptic transmission. GO:0090505 epiboly involved in wound healing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090505 The expansion of one cell sheet over other cells involved in wound healing. GO:0090506 axillary shoot meristem initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090506 axillary bud meristem initiation A developmental process that results in the initiation of an axillary shoot meristem. An axillary shoot meristem is a shoot meristem formed in the axil of a leaf. GO:0090500 endocardial cushion to mesenchymal transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090500 A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. CHEBI:90099 carboxyphosphoric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90099 CHEBI:90083 (5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl-containing glycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90083 CHEBI:90085 N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-Cer biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90085 CHEBI:90086 N-benzoyl-L-arginine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90086 CHEBI:90081 gamma-linolenoyl-containing glycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90081 CHEBI:90082 omega-3-arachidonoyl-containing glycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90082 GO:1905360 GTPase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1905360 HRAS-SOS1 complex|RASH-SOS1 complex A protein complex which is capable of GTPase activity. GO:1905361 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1905361 GO:0090509 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090509 GO:1905362 negative regulation of endosomal vesicle fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905362 down regulation of endosomal vesicle fusion|inhibition of endosomal vesicle fusion|down regulation of endosome vesicle fusion|downregulation of endosome vesicle fusion|negative regulation of endosome vesicle fusion|down-regulation of endosome vesicle fusion|down-regulation of endosomal vesicle fusion|inhibition of endosome vesicle fusion|downregulation of endosomal vesicle fusion Any process that stops, prevents or reduces the frequency, rate or extent of endosomal vesicle fusion. GO:1905363 positive regulation of endosomal vesicle fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905363 upregulation of endosome vesicle fusion|upregulation of endosomal vesicle fusion|up regulation of endosome vesicle fusion|activation of endosome vesicle fusion|positive regulation of endosome vesicle fusion|activation of endosomal vesicle fusion|up-regulation of endosomal vesicle fusion|up-regulation of endosome vesicle fusion|up regulation of endosomal vesicle fusion Any process that activates or increases the frequency, rate or extent of endosomal vesicle fusion. GO:1905364 regulation of endosomal vesicle fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905364 regulation of endosome vesicle fusion Any process that modulates the frequency, rate or extent of endosomal vesicle fusion. GO:1905365 regulation of intralumenal vesicle formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905365 regulation of endosome membrane budding Any process that modulates the frequency, rate or extent of intralumenal vesicle formation. GO:1905366 negative regulation of intralumenal vesicle formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905366 downregulation of intralumenal vesicle formation|inhibition of endosome membrane budding|down regulation of intralumenal vesicle formation|inhibition of intralumenal vesicle formation|down regulation of endosome membrane budding|downregulation of endosome membrane budding|down-regulation of intralumenal vesicle formation|down-regulation of endosome membrane budding|negative regulation of endosome membrane budding Any process that stops, prevents or reduces the frequency, rate or extent of intralumenal vesicle formation. GO:1905356 regulation of snRNA pseudouridine synthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905356 Any process that modulates the frequency, rate or extent of snRNA pseudouridine synthesis. GO:0090514 L-tyrosine transmembrane import into vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090514 The directed movement of L-tyrosine into the vacuole across the vacuolar membrane. GO:1905357 negative regulation of snRNA pseudouridine synthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905357 down-regulation of snRNA pseudouridine synthesis|inhibition of snRNA pseudouridine synthesis|down regulation of snRNA pseudouridine synthesis|downregulation of snRNA pseudouridine synthesis Any process that stops, prevents or reduces the frequency, rate or extent of snRNA pseudouridine synthesis. GO:0090515 L-glutamate transmembrane import into vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090515 The directed movement of L-glutamate into the vacuole across the vacuolar membrane. GO:1905358 positive regulation of snRNA pseudouridine synthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905358 activation of snRNA pseudouridine synthesis|up-regulation of snRNA pseudouridine synthesis|upregulation of snRNA pseudouridine synthesis|up regulation of snRNA pseudouridine synthesis Any process that activates or increases the frequency, rate or extent of snRNA pseudouridine synthesis. GO:0090512 eisosome membrane domain/MCC biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090512 A plasma membrane part that is composed of a furrow-like plasma membrane domain and associated integral transmembrane proteins. GO:1905359 protein localization to meiotic spindle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905359 protein localisation to meiotic spindle A process in which a protein is transported to, or maintained in, a location within a meiotic spindle. GO:0090513 L-histidine transmembrane import into vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090513 histidine transmembrane import into vacuole|vacuolar histidine import The directed movement of L-histidine into the vacuole across the vacuolar membrane. GO:0090518 L-arginine transmembrane import into vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090518 arginine transmembrane import into vacuole|vacuolar arginine import The directed movement of L-arginine into the vacuole across the vacuolar membrane. GO:0090519 anoxia protection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090519 Any process in which an organism or cell protects itself from anoxia, which may also result in resistance to repeated exposure to anoxia. GO:0090516 L-serine transmembrane import into vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090516 The directed movement of L-serine into the vacuole across the vacuolar membrane. GO:0090517 L-lysine transmembrane import into vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090517 lysine transmembrane import into vacuole|vacuolar lysine import The directed movement of L-lysine into the vacuole across the vacuolar membrane. GO:0090510 anticlinal cell division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090510 A cell division process where the division plane is perpendicular to the surface of the organ. It adds cells to the existing cell layer or cell file. GO:0090511 periclinal cell division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090511 A cell division process where the division plane is parallel to the surface of the organ. It creates a new cell layer or cell file. CHEBI:16062 N-acyl-D-mannosamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16062 CHEBI:16060 10-deoxysarpagine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16060 GO:2000346 negative regulation of hepatocyte proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000346 Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte proliferation. GO:2000347 positive regulation of hepatocyte proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000347 Any process that activates or increases the frequency, rate or extent of hepatocyte proliferation. GO:2000348 regulation of CD40 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000348 regulation of CD40 signalling pathway Any process that modulates the frequency, rate or extent of signaling via the CD40 signaling pathway. GO:2000349 negative regulation of CD40 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000349 negative regulation of CD40 signalling pathway Any process that stops, prevents or reduces the frequency, rate or extent of signaling via the CD40 signaling pathway. GO:0016507 mitochondrial fatty acid beta-oxidation multienzyme complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016507 trifunctional enzyme|fatty acid beta-oxidation multienzyme complex A complex that includes the long-chain 3-hydroxyacyl-CoA dehydrogenase and long-chain enoyl-CoA hydratase activities in two subunits (alpha and beta), catalyzing two steps of the fatty acid beta-oxidation cycle within the mitochondrial matrix. GO:0016508 long-chain-enoyl-CoA hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016508 Reactome:R-HSA-390252|Reactome:R-HSA-2066778|EC:4.2.1.74|MetaCyc:LONG-CHAIN-ENOYL-COA-HYDRATASE-RXN|Reactome:R-HSA-2066780|Reactome:R-HSA-389986|Reactome:R-HSA-6809263 long-chain enoyl coenzyme A hydratase activity|long-chain-(3S)-3-hydroxyacyl-CoA hydro-lyase activity Catalysis of the reaction: a long-chain (3S)-3-hydroxyacyl-CoA = a long-chain trans-2-enoyl-CoA + H2O. A long-chain acyl-CoA is an acyl-CoA thioester where the acyl chain contains 13 to 22 carbon atoms. GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016509 RHEA:52656|Reactome:R-HSA-548818|MetaCyc:1.1.1.211-RXN|EC:1.1.1.211 long-chain-(S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase activity|LCHAD|long-chain 3-hydroxyacyl coenzyme A dehydrogenase activity|beta-hydroxyacyl-CoA dehydrogenase activity Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD(P)+ = 3-oxoacyl-CoA + NAD(P)H + H+, where the acyl group is a long-chain fatty acid residue. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22. GO:0016503 pheromone receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016503 Combining with a pheromone to initiate a change in cell activity. A pheromone is a substance used in olfactory communication between organisms of the same species eliciting a change in sexual or social behavior. GO:0016504 peptidase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016504 Reactome:R-HSA-168865 protease activator activity Binds to and increases the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds. GO:2000340 positive regulation of chemokine (C-X-C motif) ligand 1 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000340 positive regulation of KC production|positive regulation of keratinocyte derived chemokine production|positive regulation of CXCL1 production|positive regulation of SCYB1 production Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production. GO:0016505 peptidase activator activity involved in apoptotic process biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016505 apoptotic protease activator activity Increases the activity of a peptidase that is involved in the apoptotic process. GO:2000341 regulation of chemokine (C-X-C motif) ligand 2 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000341 regulation of chemokine (C-C motif) ligand 2 secretion|regulation of MIP2 production|regulation of CCL2 secretion|chemokine (C-C motif) ligand 2 secretion|regulation of CXCL2 production|regulation of SCYB2 production|regulation of MIP-2 production Any process that modulates the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production. GO:0016506 obsolete apoptosis activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016506 apoptosis activator activity OBSOLETE. The function held by products which directly activate any step in the process of apoptosis. GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000342 negative regulation of CXCL2 production|negative regulation of MIP-2 production|negative regulation of SCYB2 production|negative regulation of MIP2 production|inhibition of CCL2 secretion|negative regulation of chemokine (C-C motif) ligand 2 secretion|inhibition of chemokine (C-C motif) ligand 2 secretion Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production. GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000343 positive regulation of CCL2 secretion|positive regulation of MIP2 production|positive regulation of CXCL2 production|positive regulation of MIP-2 production|positive regulation of SCYB2 production|positive regulation of chemokine (C-C motif) ligand 2 secretion Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production. GO:0016500 protein-hormone receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016500 Combining with a protein hormone to initiate a change in cell activity. GO:2000344 positive regulation of acrosome reaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000344 Any process that activates or increases the frequency, rate or extent of the acrosome reaction. CHEBI:31697 indolin-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_31697 GO:0016501 prostacyclin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016501 PGI receptor activity|PGI(2) receptor activity|prostaglandin I receptor activity Combining with prostacyclin (PGI(2)) to initiate a change in cell activity. GO:2000345 regulation of hepatocyte proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000345 Any process that modulates the frequency, rate or extent of hepatocyte proliferation. GO:0016502 nucleotide receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016502 Combining with a nucleotide and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A nucleotide is a compound that consists of a nucleoside esterified with a phosphate molecule. CHEBI:16058 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16058 CHEBI:16057 prenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16057 CHEBI:16054 2-benzylsuccinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16054 CHEBI:16055 aldehydo-L-rhamnose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16055 CHEBI:16052 propene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16052 CHEBI:16053 1beta,3beta,4alpha-p-menthane-3,8-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16053 CHEBI:16050 N-acetylisatin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16050 CHEBI:16051 poly(ribitol phosphate) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16051 GO:2000357 negative regulation of kidney smooth muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000357 Any process that stops, prevents or reduces the frequency, rate or extent of kidney smooth muscle cell differentiation. CHEBI:65003 2-deoxy-scyllo-inosamine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65003 CHEBI:65004 (-)-secoisolariciresinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65004 GO:2000358 positive regulation of kidney smooth muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000358 Any process that activates or increases the frequency, rate or extent of kidney smooth muscle cell differentiation. GO:2000359 regulation of binding of sperm to zona pellucida biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000359 regulation of ZPG binding Any process that modulates the frequency, rate or extent of binding of sperm to the zona pellucida. CHEBI:65006 inositol phosphomannosylinositol phosphophytoceramide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65006 GO:0016518 interleukin-14 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016518 IL-14R|IL-14 receptor activity Combining with interleukin-14 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0016519 gastric inhibitory peptide receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016519 GIP receptor activity|glucose-dependent insulinotropic polypeptide receptor activity Combining with gastric inhibitory peptide (GIP) and transmitting the signal across the membrane to activate an associated G-protein. CHEBI:65000 mannosylinositol phosphophytoceramide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65000 CHEBI:65001 EC 3.1.1.3 (triacylglycerol lipase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65001 CHEBI:65002 3-ammonio-2,3-dideoxy-scyllo-inosose(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65002 GO:0016514 SWI/SNF complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016514 SWI-SNF complex A SWI/SNF-type complex that contains 8 to 14 proteins, including both conserved (core) and nonconserved components; contains the ATPase product of the yeast SNF2 or mammalian SMARCA4/BAF190A/BRG1 gene, or an ortholog thereof. GO:2000350 positive regulation of CD40 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000350 positive regulation of CD40 signalling pathway Any process that activates or increases the frequency, rate or extent of signaling via the CD40 signaling pathway. GO:0016515 interleukin-13 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016515 IL-13 receptor activity|IL-13R Combining with interleukin-13 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:2000351 regulation of endothelial cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000351 regulation of programmed cell death of endothelial cells by apoptosis|regulation of apoptosis of endothelial cells|regulation of endothelial cell programmed cell death by apoptosis|regulation of programmed cell death, endothelial cells|regulation of endothelial cell apoptosis|regulation of killing of endothelial cells Any process that modulates the frequency, rate or extent of endothelial cell apoptotic process. GO:0016516 interleukin-4 receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016516 IL-4 receptor complex A protein complex that binds interleukin-4 (IL-4) and consists of an alpha chain that binds IL-4 with high affinity and a gamma common chain that also forms part of the interleukin-2 receptor. GO:0016517 interleukin-12 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016517 IL-12 receptor activity|IL-12R Combining with interleukin-12 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:2000352 negative regulation of endothelial cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000352 negative regulation of apoptosis of endothelial cells|negative regulation of programmed cell death, endothelial cells|negative regulation of endothelial cell apoptosis|negative regulation of programmed cell death of endothelial cells by apoptosis|negative regulation of killing of endothelial cells|negative regulation of endothelial cell programmed cell death by apoptosis Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell apoptotic process. GO:2000353 positive regulation of endothelial cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000353 positive regulation of apoptosis of endothelial cells|positive regulation of programmed cell death of endothelial cells by apoptosis|positive regulation of programmed cell death, endothelial cells|positive regulation of endothelial cell apoptosis|positive regulation of endothelial cell programmed cell death by apoptosis|positive regulation of killing of endothelial cells Any process that activates or increases the frequency, rate or extent of endothelial cell apoptotic process. GO:0016510 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016510 GO:2000354 regulation of ovarian follicle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000354 regulation of follicular phase Any process that modulates the frequency, rate or extent of ovarian follicle development. CHEBI:65008 6'-oxoparomamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65008 GO:0016511 obsolete endothelin-converting enzyme activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016511 endothelin-converting enzyme activity OBSOLETE. (Was not defined before being made obsolete). GO:0016512 obsolete endothelin-converting enzyme 1 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016512 ECE-1 activity|endothelin-converting enzyme 1 activity OBSOLETE. Catalysis of the formation of endothelin 1 by cleavage of the Trp21-Val22 bond in the precursor. CHEBI:16049 CDP-abequose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16049 GO:2000355 negative regulation of ovarian follicle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000355 negative regulation of follicular phase Any process that stops, prevents or reduces the frequency, rate or extent of ovarian follicle development. CHEBI:65009 indol-3-ylmethylamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65009 GO:0016513 core-binding factor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016513 PEPB2 complex|CBF complex|AML1 complex A heterodimeric transcription factor complex that contains an alpha subunit (Runx1, Runx2 or Runx3 in human) that binds DNA and a non-DNA-binding beta subunit (CBFbeta), and binds to a consensus sequence 5'-YGYGGTY-3' found in several enhancers and promoters; the beta subunit enhances the DNA binding of the alpha subunit. GO:2000356 regulation of kidney smooth muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000356 Any process that modulates the frequency, rate or extent of kidney smooth muscle cell differentiation. CHEBI:16047 Lys-tRNA(Lys) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16047 CHEBI:16048 FMNH2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16048 CHEBI:16046 alpha-D-galactosyl undecaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16046 CHEBI:16044 L-methionine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16044 CHEBI:16042 halide anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16042 CHEBI:16083 (S)-3-(indol-3-yl)-2-oxobutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16083 CHEBI:16084 beta-D-fructofuranose 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16084 CHEBI:16081 dTDP-L-dihydrostreptose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16081 CHEBI:16082 UDP-alpha-D-xylose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16082 CHEBI:16080 gamma-amino-beta-hydroxybutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16080 GO:2000368 positive regulation of acrosomal vesicle exocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000368 positive regulation of acrosome exocytosis|positive regulation of acrosomal granule exocytosis Any process that activates or increases the frequency, rate or extent of acrosomal vesicle exocytosis. GO:2000369 regulation of clathrin-dependent endocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000369 regulation of clathrin-dependent endocytosis|regulation of clathrin coated pit-dependent endocytosis|regulation of clathrin-mediated endocytosis Any process that modulates the frequency, rate or extent of clathrin-mediated endocytosis. CHEBI:65015 paromamine(3+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65015 CHEBI:65016 6'-oxoparomamine(3+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65016 CHEBI:65010 2'-N-acetylparomamine(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65010 CHEBI:65011 nicotine blue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65011 CHEBI:65013 extended quinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65013 GO:2000360 negative regulation of binding of sperm to zona pellucida biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000360 negative regulation of ZPG binding Any process that stops, prevents or reduces the frequency, rate or extent of binding of sperm to the zona pellucida. GO:2000361 regulation of prostaglandin-E synthase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000361 regulation of Prostaglandin-H(2) E-isomerase activity|regulation of endoperoxide isomerase activity|regulation of prostaglandin endoperoxide E isomerase activity|regulation of prostaglandin H-E isomerase activity|regulation of (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate E-isomerase activity|regulation of PGE2 isomerase activity|regulation of PGE isomerase activity|regulation of prostaglandin-H2 E-isomerase activity|regulation of PGH-PGE isomerase activity|regulation of prostaglandin R-prostaglandin E isomerase activity|regulation of prostaglandin endoperoxide E2 isomerase activity Any process that modulates the frequency, rate or extent of prostaglandin-E synthase activity. GO:2000362 negative regulation of prostaglandin-E synthase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000362 negative regulation of prostaglandin-H2 E-isomerase activity|negative regulation of (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate E-isomerase activity|negative regulation of PGE isomerase activity|negative regulation of prostaglandin R-prostaglandin E isomerase activity|negative regulation of PGH-PGE isomerase activity|negative regulation of endoperoxide isomerase activity|negative regulation of Prostaglandin-H(2) E-isomerase activity|negative regulation of prostaglandin endoperoxide E isomerase activity|negative regulation of prostaglandin endoperoxide E2 isomerase activity|negative regulation of PGE2 isomerase activity|negative regulation of prostaglandin H-E isomerase activity Any process that stops, prevents or reduces the frequency, rate or extent of prostaglandin-E synthase activity. GO:2000363 positive regulation of prostaglandin-E synthase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000363 positive regulation of prostaglandin H-E isomerase activity|positive regulation of (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate E-isomerase activity|positive regulation of endoperoxide isomerase activity|positive regulation of Prostaglandin-H(2) E-isomerase activity|positive regulation of prostaglandin endoperoxide E isomerase activity|positive regulation of PGE isomerase activity|positive regulation of PGH-PGE isomerase activity|positive regulation of prostaglandin R-prostaglandin E isomerase activity|positive regulation of PGE2 isomerase activity|positive regulation of prostaglandin endoperoxide E2 isomerase activity|positive regulation of prostaglandin-H2 E-isomerase activity Any process that activates or increases the frequency, rate or extent of prostaglandin-E synthase activity. CHEBI:65018 2'-N-acetylparomamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65018 GO:2000364 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2000364 GO:2000365 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2000365 GO:2000366 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2000366 GO:2000367 regulation of acrosomal vesicle exocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000367 regulation of acrosomal granule exocytosis|regulation of acrosome exocytosis Any process that modulates the frequency, rate or extent of acrosomal vesicle exocytosis. CHEBI:16079 benzyl 2-methyl-3-oxobutanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16079 CHEBI:16076 11alpha-hydroxyprogesterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16076 CHEBI:16077 D-glucopyranose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16077 CHEBI:16074 5beta-cholestan-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16074 CHEBI:16072 maleimide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16072 CHEBI:16073 N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-D-glucosaminyl undecaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16073 CHEBI:16070 1,5-anhydro-D-glucitol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16070 CHEBI:80657 all-trans-18-hydroxyretinoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_80657 CHEBI:80658 5,6-epoxyretinoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_80658 GO:2000379 positive regulation of reactive oxygen species metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000379 positive regulation of reactive oxygen species metabolism|positive regulation of ROS metabolic process Any process that activates or increases the frequency, rate or extent of reactive oxygen species metabolic process. CHEBI:80656 all-trans-4-oxoretinoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_80656 CHEBI:65027 3-amino-2,3-dideoxy-scyllo-inosose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65027 CHEBI:65028 ribostamycin(4+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65028 CHEBI:80651 1,2-ditetradecanoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_80651 CHEBI:65023 anti-asthmatic agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65023 GO:2000371 regulation of DNA topoisomerase (ATP-hydrolyzing) activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000371 regulation of DNA topoisomerase II|regulation of topoisomerase II|regulation of topoisomerase|regulation of DNA topoisomerase IV activity|regulation of DNA topoisomerase type II activity|regulation of type II DNA topoisomerase activity|regulation of deoxyribonucleic topoisomerase activity|regulation of deoxyribonucleate topoisomerase|regulation of DNA topoisomerase (ATP-hydrolysing) Any process that modulates the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity. GO:2000372 negative regulation of DNA topoisomerase (ATP-hydrolyzing) activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000372 negative regulation of deoxyribonucleic topoisomerase activity|negative regulation of deoxyribonucleate topoisomerase|negative regulation of DNA topoisomerase (ATP-hydrolysing)|negative regulation of type II DNA topoisomerase activity|negative regulation of DNA topoisomerase type II activity|negative regulation of topoisomerase|negative regulation of DNA topoisomerase IV activity|negative regulation of DNA topoisomerase II|negative regulation of topoisomerase II Any process that stops, prevents or reduces the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity. GO:2000373 positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000373 positive regulation of topoisomerase II|positive regulation of deoxyribonucleate topoisomerase|positive regulation of deoxyribonucleic topoisomerase activity|positive regulation of DNA topoisomerase (ATP-hydrolysing)|positive regulation of type II DNA topoisomerase activity|positive regulation of DNA topoisomerase type II activity|positive regulation of topoisomerase|positive regulation of DNA topoisomerase IV activity|positive regulation of DNA topoisomerase II Any process that activates or increases the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity. GO:2000374 regulation of oxygen metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000374 regulation of oxygen metabolism|regulation of diatomic oxygen metabolic process Any process that modulates the frequency, rate or extent of oxygen metabolic process. GO:2000375 negative regulation of oxygen metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000375 negative regulation of diatomic oxygen metabolic process|negative regulation of oxygen metabolism Any process that stops, prevents or reduces the frequency, rate or extent of oxygen metabolic process. CHEBI:65029 trihydroxycyclohexanone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65029 GO:2000376 positive regulation of oxygen metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000376 positive regulation of diatomic oxygen metabolic process|positive regulation of oxygen metabolism Any process that activates or increases the frequency, rate or extent of oxygen metabolic process. GO:2000377 regulation of reactive oxygen species metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000377 regulation of reactive oxygen species metabolism|regulation of ROS metabolic process Any process that modulates the frequency, rate or extent of reactive oxygen species metabolic process. GO:2000378 negative regulation of reactive oxygen species metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000378 negative regulation of ROS metabolic process|negative regulation of reactive oxygen species metabolism Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species metabolic process. CHEBI:16069 1H-imidazole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16069 CHEBI:16067 1D-myo-inositol 1,4,5,6-tetrakisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16067 CHEBI:16068 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16068 CHEBI:16065 scopolin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16065 CHEBI:16066 11-cis-retinal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16066 CHEBI:16063 limonin 17-beta-D-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16063 GO:2000370 positive regulation of clathrin-dependent endocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000370 positive regulation of clathrin-dependent endocytosis|positive regulation of clathrin-mediated endocytosis|positive regulation of clathrin coated pit-dependent endocytosis Any process that activates or increases the frequency, rate or extent of clathrin-mediated endocytosis. CHEBI:16064 keto-3-deoxy-D-manno-octulosonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16064 CHEBI:65030 2'''-acetyl-6'''-hydroxyneomycin C(4+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65030 CHEBI:65031 6'''-hydroxyneomycin C(5+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65031 GO:2000302 positive regulation of synaptic vesicle exocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000302 Any process that activates or increases the frequency, rate or extent of synaptic vesicle exocytosis. CHEBI:80666 norbelladine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_80666 CHEBI:65036 didehydroagroclavine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65036 GO:2000303 regulation of ceramide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000303 regulation of ceramide synthesis|regulation of ceramide formation|regulation of ceramide biosynthesis|regulation of ceramide anabolism Any process that modulates the frequency, rate or extent of a ceramide biosynthetic process. CHEBI:65037 miltiradiene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65037 CHEBI:80667 4'-O-methylnorbelladine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_80667 GO:2000304 positive regulation of ceramide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000304 positive regulation of ceramide biosynthesis|positive regulation of ceramide anabolism|positive regulation of ceramide synthesis|positive regulation of ceramide formation Any process that activates or increases the frequency, rate or extent of ceramide biosynthetic process. GO:2000305 semaphorin-plexin signaling pathway involved in regulation of photoreceptor cell axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000305 semaphorin-plexin signaling pathway of regulation of photoreceptor cell axon guidance|semaphorin-plexin signaling pathway of regulation of photoreceptor cell axon pathfinding|semaphorin-plexin signalling pathway of regulation of photoreceptor cell axon guidance|semaphorin-plexin signalling pathway of regulation of photoreceptor cell axon pathfinding Any semaphorin-plexin signaling pathway that is involved in regulation of photoreceptor cell axon guidance. GO:2000306 positive regulation of photomorphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000306 positive regulation of plant development in response to light Any process that activates or increases the frequency, rate or extent of photomorphogenesis. CHEBI:65032 dihydrochanoclavine-I aldehyde(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65032 GO:2000307 regulation of tumor necrosis factor (ligand) superfamily member 11 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000307 regulation of TNFSF11 production|regulation of RANKL production Any process that modulates the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production. GO:2000308 negative regulation of tumor necrosis factor (ligand) superfamily member 11 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000308 negative regulation of TNFSF11 production|negative regulation of RANKL production Any process that stops, prevents or reduces the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production. CHEBI:65034 6,8-dimethyl-6,7-didehydroergolin-6-ium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65034 CHEBI:65035 festuclavine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65035 GO:2000309 positive regulation of tumor necrosis factor (ligand) superfamily member 11 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000309 positive regulation of TNFSF11 production|positive regulation of RANKL production Any process that activates or increases the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production. CHEBI:16018 acyl-[acyl-carrier protein] biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16018 CHEBI:16019 prenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16019 GO:2000300 regulation of synaptic vesicle exocytosis biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_2000300 Any process that modulates the frequency, rate or extent of synaptic vesicle exocytosis. CHEBI:16016 dihydroxyacetone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16016 GO:2000301 negative regulation of synaptic vesicle exocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000301 Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle exocytosis. CHEBI:16017 benzyl thiocyanate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16017 CHEBI:16015 L-glutamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16015 CHEBI:16013 5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16013 CHEBI:16010 5-oxoproline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16010 CHEBI:16011 2-ethylhexan-1-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16011 OBO:CP_0000040 reniform nucleus biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/CP_0000040 A concave nucleus shape where the indentation is smaller than half of the distance to the farthest nuclear margin. CHEBI:65040 UDP-2-acetamido-2-deoxy-alpha-D-glucuronate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65040 CHEBI:65041 dihydrochanoclavine-I aldehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65041 CHEBI:65042 agroclavine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65042 NCBITaxon:451864 Dikarya organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_451864 OBO:CP_0000043 cartwheel heterochromatin biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/CP_0000043 Heterochromatin that is arranged in a carthwheel pattern. GO:2000313 regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000313 regulation of fibroblast growth factor receptor signalling pathway involved in neural plate anterior/posterior pattern formation Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation. CHEBI:65047 UDP-2-acetamido-2-deoxy-alpha-D-glucuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65047 GO:2000314 negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000314 negative regulation of fibroblast growth factor receptor signalling pathway involved in neural plate anterior/posterior pattern formation Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation. CHEBI:65048 cyclo(tyrosyl-tyrosyl) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65048 GO:2000315 positive regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000315 positive regulation of fibroblast growth factor receptor signalling pathway involved in neural plate anterior/posterior pattern formation Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation. GO:2000316 regulation of T-helper 17 type immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000316 regulation of Th17 immune response Any process that modulates the frequency, rate or extent of T-helper 17 type immune response. GO:2000317 negative regulation of T-helper 17 type immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000317 negative regulation of Th17 immune response Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 type immune response. CHEBI:65043 6'''-hydroxyneomycin C biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65043 GO:2000318 positive regulation of T-helper 17 type immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000318 positive regulation of Th17 immune response Any process that activates or increases the frequency, rate or extent of T-helper 17 type immune response. CHEBI:65044 2'''-acetyl-6'''-hydroxyneomycin C biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65044 NCBITaxon:451866 Taphrinomycotina organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_451866 CHEBI:65045 festuclavine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65045 GO:2000319 regulation of T-helper 17 cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000319 regulation of T-helper 17 cell development Any process that modulates the frequency, rate or extent of T-helper 17 cell differentiation. CHEBI:65046 2-deoxy-scyllo-inosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65046 CHEBI:16009 9-riburonosyladenine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16009 CHEBI:16007 methanethiol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16007 GO:2000310 regulation of NMDA receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity Any process that modulates the frequency, rate or extent of N-methyl-D-aspartate selective glutamate receptor activity. CHEBI:16008 salicylaldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16008 GO:2000311 regulation of AMPA receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity Any process that modulates the frequency, rate or extent of AMPA selective glutamate receptor activity. CHEBI:16005 methylarsonate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16005 GO:2000312 regulation of kainate selective glutamate receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000312 Any process that modulates the frequency, rate or extent of kainate selective glutamate receptor activity. CHEBI:16003 (R)-3-(4-hydroxyphenyl)lactic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16003 CHEBI:16004 (R)-lactate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16004 CHEBI:16001 3-phospho-D-glyceroyl dihydrogen phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16001 CHEBI:16002 D-glucaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16002 CHEBI:16000 ethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16000 CHEBI:16040 cytosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16040 CHEBI:65052 tetracosanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65052 CHEBI:65053 EC 4.1.1.19 (arginine decarboxylase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65053 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000324 positive regulation of glucocorticoid receptor signalling pathway Any process that activates or increases the frequency, rate or extent of glucocorticoid receptor signaling pathway. GO:2000325 obsolete regulation of nuclear receptor coactivator activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000325 regulation of ligand-dependent nuclear receptor transcription co-activator activity|regulation of ligand-dependent nuclear receptor transcription coactivator activity|regulation of nuclear receptor transcription coactivator activity OBSOLETE. Any process that modulates the frequency, rate or extent of ligand-dependent nuclear receptor transcription coactivator activity. CHEBI:65059 docosanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65059 GO:2000326 obsolete negative regulation of nuclear receptor transcription coactivator activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000326 negative regulation of ligand-dependent nuclear receptor transcription co-activator activity|negative regulation of ligand-dependent nuclear receptor transcription coactivator activity OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of ligand-dependent nuclear receptor transcription coactivator activity. GO:2000327 obsolete positive regulation of nuclear receptor transcription coactivator activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000327 positive regulation of ligand-dependent nuclear receptor transcription coactivator activity|positive regulation of ligand-dependent nuclear receptor transcription co-activator activity OBSOLETE. Any process that activates or increases the frequency, rate or extent of ligand-dependent nuclear receptor transcription coactivator activity. GO:2000328 regulation of T-helper 17 cell lineage commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000328 regulation of T-helper 17 cell fate commitment|regulation of Th17 fate commitment|regulation of Th17 cell lineage commitment Any process that modulates the frequency, rate or extent of T-helper 17 cell lineage commitment. GO:2000329 negative regulation of T-helper 17 cell lineage commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000329 negative regulation of T-helper 17 cell fate commitment|negative regulation of Th17 fate commitment|negative regulation of Th17 cell lineage commitment Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell lineage commitment. CHEBI:65055 1-octadecanoyl-2-acyl-sn-glycero-3-phospho-1D-myo-inositol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65055 CHEBI:65056 EC 3.1.3.11 (fructose-bisphosphatase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65056 CHEBI:65057 adenosine A1 receptor agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65057 GO:2000320 negative regulation of T-helper 17 cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000320 negative regulation of T-helper 17 cell development Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell differentiation. GO:2000321 positive regulation of T-helper 17 cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000321 positive regulation of T-helper 17 cell development Any process that activates or increases the frequency, rate or extent of T-helper 17 cell differentiation. GO:2000322 regulation of glucocorticoid receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000322 regulation of glucocorticoid receptor signalling pathway Any process that modulates the frequency, rate or extent of glucocorticoid receptor signaling pathway. CHEBI:16038 phosphatidylethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16038 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000323 negative regulation of glucocorticoid receptor signalling pathway Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid receptor signaling pathway. CHEBI:16039 ITP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16039 OBO:CP_0000037 increased nucleus size biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/CP_0000037 A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell. CHEBI:16036 ethyl (S)-3-hydroxyhexanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16036 CHEBI:16037 2-nitropropane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16037 CHEBI:16034 phosphoguanidinoacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16034 OBO:CP_0000035 polychromatophilic cytoplasm biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/CP_0000035 Cytoplasm that exhibits affinity for both basic and acid stains under specific pH conditions. CHEBI:16035 2'-hydroxy-2,3-dihydrodaidzein biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16035 CHEBI:16032 androsterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16032 CHEBI:16030 acyldolichol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16030 OBO:CP_0000039 banded nucleus biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/CP_0000039 A concave nuclear shape where the nucleus is indented to more than half the distance to the farthest nuclear margin, but in no area is the chromatin condensed to a single filament. CHEBI:16031 indole-3-acetamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16031 CHEBI:65061 2,5-diketopiperazines biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65061 CHEBI:65063 cyclo(L-tyrosyl-L-tyrosyl) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65063 CHEBI:65064 EC 2.1.1.79 (cyclopropane-fatty-acyl-phospholipid synthase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65064 CHEBI:65060 (9Z)-myristoleoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65060 GO:2000335 regulation of endothelial microparticle formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000335 regulation of endothelial microparticle generation|regulation of endothelial microparticle release Any process that modulates the frequency, rate or extent of endothelial microparticle formation. CHEBI:65069 2-deoxystreptamine(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65069 GO:2000336 negative regulation of endothelial microparticle formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000336 negative regulation of endothelial microparticle release|negative regulation of endothelial microparticle generation Any process that stops, prevents or reduces the frequency, rate or extent of endothelial microparticle formation. GO:2000337 positive regulation of endothelial microparticle formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000337 positive regulation of endothelial microparticle release|positive regulation of endothelial microparticle generation Any process that activates or increases the frequency, rate or extent of endothelial microparticle formation. GO:2000338 regulation of chemokine (C-X-C motif) ligand 1 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000338 regulation of CXCL1 production|regulation of SCYB1 production|regulation of KC production|regulation of keratinocyte derived chemokine production Any process that modulates the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production. GO:2000339 negative regulation of chemokine (C-X-C motif) ligand 1 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000339 negative regulation of KC production|negative regulation of keratinocyte derived chemokine production|negative regulation of SCYB1 production|negative regulation of CXCL1 production Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production. CHEBI:65065 EC 2.1.1.72 [site-specific DNA-methyltransferase (adenine-specific)] inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65065 CHEBI:65066 trans,octacis-decaprenylphospho-beta-D-arabinofuranose(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65066 CHEBI:65067 trans,octacis-decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65067 CHEBI:65068 6'''-oxoneomycin C(5+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65068 GO:2000330 positive regulation of T-helper 17 cell lineage commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000330 positive regulation of Th17 fate commitment|positive regulation of Th17 cell lineage commitment|positive regulation of T-helper 17 cell fate commitment Any process that activates or increases the frequency, rate or extent of T-helper 17 cell lineage commitment. CHEBI:80690 Thyroglobulin triiodothyronine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_80690 PR:000003237 14-3-3 protein biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000003237 A protein that is a stand alone version of the 14-3-3 protein (Pfam:PF00244) domain. CHEBI:16029 N(alpha),N(alpha)-dimethyl-L-histidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16029 GO:2000331 regulation of terminal button organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000331 regulation of terminal button organisation|regulation of terminal bouton organization|regulation of bouton organization|regulation of synaptic bouton organization|regulation of presynaptic bouton organization Any process that modulates the frequency, rate or extent of terminal button organization. GO:2000332 regulation of blood microparticle formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000332 regulation of microparticle release|regulation of microparticle generation Any process that modulates the frequency, rate or extent of blood microparticle formation. GO:2000333 negative regulation of blood microparticle formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000333 negative regulation of microparticle release|negative regulation of microparticle generation Any process that stops, prevents or reduces the frequency, rate or extent of blood microparticle formation. CHEBI:16027 adenosine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16027 GO:2000334 positive regulation of blood microparticle formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000334 positive regulation of microparticle release|positive regulation of microparticle generation Any process that activates or increases the frequency, rate or extent of blood microparticle formation. CHEBI:16028 L-2,4-diaminobutyrate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16028 OBO:CP_0000027 acidophilic cytoplasm biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/CP_0000027 eosinophilic Cytoplasm that exhibits a characteristic staining and color, red or pink, with Eosin stain. CHEBI:16026 LL-2,6-diaminopimelic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16026 CHEBI:16023 D-erythrulose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16023 NCBITaxon:147554 Schizosaccharomycetes organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_147554 Archiascomycota CHEBI:16024 D-mannose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16024 CHEBI:16021 oleandomycin 2'-O-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16021 CHEBI:16022 CDP-ribitol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16022 OBO:CP_0000028 basophilic cytoplasm biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/CP_0000028 Cytoplasm that exhibits molecular interaction for basic dyes under specific pH conditions. CHEBI:16020 1-methyladenosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16020 GO:0016587 Isw1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016587 A protein complex that contains an Isw1 subunit from the ISWI-family of ATPases and acts to modify chromatin structure. GO:0016588 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016588 GO:0016589 NURF complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016589 nucleosome remodeling factor complex An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2L in mammals), a NURF301 homolog (BPTF in humans), and additional subunits, though the composition of these additional subunits varies slightly with species. NURF is involved in regulation of transcription from TRNA polymerase II promoters. GO:0016583 obsolete nucleosome modeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016583 nucleosome modeling OBSOLETE. (Was not defined before being made obsolete). GO:0016584 nucleosome positioning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016584 nucleosome spacing Ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another. GO:0016585 obsolete chromatin remodeling complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016585 chromatin remodelling complex|chromatin remodeling complex|nucleosome remodeling complex OBSOLETE. Any complex that mediates dynamic changes in eukaryotic chromatin. GO:0016586 RSC-type complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016586 PBAF complex|Polybromo- and BAF containing complex|SWI/SNF complex B A SWI/SNF-type complex that contains a bromodomain containing-protein, such as yeast Rsc1 or Rsc4 or mammalian PB1/BAF180. The RSC complex is generally recruited to RNA polymerase III promoters and is specifically recruited to RNA polymerase II promoters by transcriptional activators and repressors; it is also involved in non-homologous end joining. GO:0016580 Sin3 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016580 A multiprotein complex that functions broadly in eukaryotic organisms as a transcriptional repressor of protein-coding genes, through the gene-specific deacetylation of histones. Amongst its subunits, the Sin3 complex contains Sin3-like proteins, and a number of core proteins that are shared with the NuRD complex (including histone deacetylases and histone binding proteins). The Sin3 complex does not directly bind DNA itself, but is targeted to specific genes through protein-protein interactions with DNA-binding proteins. GO:0016581 NuRD complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016581 nucleosome remodeling and histone deacetylation complex|Mi-2 complex|NRD complex An approximately 2 MDa multi-subunit complex that exhibits ATP-dependent chromatin remodeling activity in addition to histone deacetylase (HDAC) activity, and has been shown to establish transcriptional repression of a number of target genes in vertebrates, invertebrates and fungi. Amongst its subunits, the NuRD complex contains histone deacetylases, histone binding proteins and Mi-2-like proteins. GO:0016582 obsolete non-covalent chromatin modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016582 OBSOLETE. The alteration of DNA or protein in chromatin by the non-covalent addition or removal of chemical groups. OBO:CP_0000000 neutrophillic cytoplasm biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/CP_0000000 Cytoplasm that exhibits a characteristic staining and color, pale-pink, with Wright-Giemsa stain. GO:0016598 protein arginylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016598 protein amino acid arginylation The conjugation of arginine to the N-terminal aspartate or glutamate of a protein; required for the degradation of the protein via the ubiquitin pathway. GO:0016599 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016599 GO:0016594 glycine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016594 aminoethanoic acid binding|Gly binding|aminoacetic acid binding Interacting selectively and non-covalently with glycine, aminoethanoic acid. GO:0016595 glutamate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016595 glutamic acid binding Interacting selectively and non-covalently with glutamate, the anion of 2-aminopentanedioic acid. GO:0016596 thienylcyclohexylpiperidine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016596 TCP binding Interacting selectively and non-covalently with thienylcyclohexylpiperidine. GO:0016597 amino acid binding biolink:MolecularActivity go-plus goslim_pir|goslim_metagenomics http://purl.obolibrary.org/obo/GO_0016597 Interacting selectively and non-covalently with an amino acid, organic acids containing one or more amino substituents. GO:0016590 ACF complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016590 ATP-utilizing chromatin assembly and remodeling factor complex An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2H in mammals, Isw2 in S. cerevisiae), an ACF1 homolog, and generally no other subunits, though Xenopus is an exception with a third non-conserved subunit. ACF plays roles in regulation of RNA polymerase II transcription and in DNA replication and repair. NCBITaxon:147537 Saccharomycotina organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_147537 true yeasts GO:0016591 RNA polymerase II, holoenzyme biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0016591 DNA-directed RNA polymerase II, holoenzyme A nuclear DNA-directed RNA polymerase complex containing an RNA polymerase II core enzyme as well as additional proteins and transcription factor complexes, that are capable of promoter recognition and transcription initiation from an RNA polymerase II promoter in vivo. These additional components may include general transcription factor complexes TFIIA, TFIID, TFIIE, TFIIF, or TFIIH, as well as Mediator, SWI/SNF, GCN5, or SRBs and confer the ability to recognize promoters. GO:0016592 mediator complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016592 Wikipedia:Mediator_(coactivator) CDK8-containing TRAP/mediator complex|Srb-mediator complex|TRAP complex|L mediator complex A protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The mediator complex is required for activation of transcription of most protein-coding genes, but can also act as a transcriptional corepressor. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins. GO:0016593 Cdc73/Paf1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016593 Paf1p complex|Paf1 complex A multiprotein complex that associates with RNA polymerase II and general RNA polymerase II transcription factor complexes and may be involved in both transcriptional initiation and elongation. In Saccharomyces the complex contains Paf1p, Cdc73p, Ctr9p, Rtf1p, and Leo1p. GO:0016569 covalent chromatin modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016569 chromatin modification The alteration of DNA or protein in chromatin by the covalent addition or removal of chemical groups. GO:0016565 obsolete general transcriptional repressor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016565 general transcriptional repressor activity OBSOLETE. Any activity that stops or downregulates transcription of genes globally, and is not specific to a particular gene or gene set. GO:0016566 obsolete specific transcriptional repressor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016566 specific transcriptional repressor activity OBSOLETE. Any activity that stops or downregulates transcription of specific genes or sets of genes. GO:0016567 protein ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016567 protein ubiquitylation|protein ubiquitinylation The process in which one or more ubiquitin groups are added to a protein. GO:0016568 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016568 GO:0016561 protein import into peroxisome matrix, translocation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016561 protein translocation during protein import into peroxisome matrix|peroxisome receptor translocation|protein translocation during protein transport into peroxisome matrix|protein translocation during peroxisome matrix protein import|peroxisome matrix protein import, translocation|protein transport into peroxisome matrix, translocation The process in which proteins are moved across the peroxisomal membrane into the matrix. It is likely that the peroxisome targeting sequence receptor remains associated with cargo proteins during translocation. GO:0016562 protein import into peroxisome matrix, receptor recycling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016562 receptor recycling during protein transport into peroxisome matrix|receptor recycling during peroxisome matrix protein import|protein transport into peroxisome matrix, receptor recycling|receptor recycling during protein import into peroxisome matrix|PTS receptor recycling|peroxisome matrix protein import, receptor recycling|peroxisome receptor recycling The process in which peroxisome targeting sequence receptors dissociates from cargo proteins and are returned to the cytosol. GO:0016563 obsolete transcription activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016563 transcription activator activity|transcriptional activator activity|transcription activating factor OBSOLETE. Any transcription regulator activity required for initiation or upregulation of transcription. GO:0016564 obsolete transcription repressor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016564 transcription repressor activity|transcriptional repressor activity|negative transcriptional regulator activity OBSOLETE. Any transcription regulator activity that prevents or downregulates transcription. GO:0016560 protein import into peroxisome matrix, docking biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016560 protein docking during peroxisome matrix protein import|peroxisome matrix protein import, docking|protein transport into peroxisome matrix, docking|protein docking during protein import into peroxisome matrix|protein docking during protein transport into peroxisome matrix|peroxisome receptor docking The process in which a complex formed of a peroxisome targeting sequence (PTS) receptor bound to a PTS-bearing protein docks with translocation machinery in the peroxisomal membrane. GO:0016576 histone dephosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016576 The modification of histones by removal of phosphate groups. GO:0016577 histone demethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016577 The modification of histones by removal of methyl groups. GO:0016578 histone deubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016578 histone deubiquitylation|histone deubiquitinylation The modification of histones by removal of ubiquitin groups. GO:0016579 protein deubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016579 protein deubiquitylation|protein deubiquitinylation|deubiquitination The removal of one or more ubiquitin groups from a protein. GO:0016572 histone phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016572 The modification of histones by addition of phosphate groups. GO:0016573 histone acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016573 The modification of a histone by the addition of an acetyl group. GO:0016574 histone ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016574 histone ubiquitylation|histone ubiquitinylation The modification of histones by addition of ubiquitin groups. GO:0016575 histone deacetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016575 The modification of histones by removal of acetyl groups. GO:0016570 histone modification biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0016570 Wikipedia:Histone#Histone_modifications_in_chromatin_regulation The covalent alteration of one or more amino acid residues within a histone protein. GO:0016571 histone methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016571 Wikipedia:Histone_methylation The modification of histones by addition of methyl groups. GO:2000382 positive regulation of mesoderm development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000382 Any process that activates or increases the frequency, rate or extent of mesoderm development. GO:0016547 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016547 GO:0016548 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016548 GO:2000383 regulation of ectoderm development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000383 Any process that modulates the frequency, rate or extent of ectoderm development. GO:2000384 negative regulation of ectoderm development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000384 Any process that stops, prevents or reduces the frequency, rate or extent of ectoderm development. GO:0016549 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016549 GO:2000385 positive regulation of ectoderm development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000385 Any process that activates or increases the frequency, rate or extent of ectoderm development. GO:0016543 male courtship behavior, orientation prior to leg tapping and wing vibration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016543 male courtship behaviour, orientation|male courtship behavior, orientation|male courtship behaviour, orientation prior to leg tapping and wing vibration The process during courtship, where the male orients towards a potential partner. An example of this is found in Drosophila melanogaster. GO:2000386 positive regulation of ovarian follicle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000386 positive regulation of follicular phase Any process that activates or increases the frequency, rate or extent of ovarian follicle development. GO:0016544 male courtship behavior, tapping to detect pheromone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016544 male courtship behavior, tapping|male courtship behaviour, tapping to detect pheromone|male courtship behaviour, tapping The process during courtship where the male insect taps the female with his frontal leg. An example of this is found in Drosophila melanogaster. GO:2000387 regulation of antral ovarian follicle growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000387 Any process that modulates the frequency, rate or extent of antral ovarian follicle growth. GO:0016545 male courtship behavior, veined wing vibration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016545 male courtship behavior, wing vibration|male courtship behaviour, veined wing vibration|male courtship behaviour, wing vibration The process during courtship where the male insect vibrates his wings. An example of this is found in Drosophila melanogaster. GO:2000388 positive regulation of antral ovarian follicle growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000388 Any process that activates or increases the frequency, rate or extent of antral ovarian follicle growth. GO:0016546 male courtship behavior, proboscis-mediated licking biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016546 male courtship behaviour, proboscis-mediated licking|male courtship behavior, licking|male courtship behaviour, licking The process during courtship where the male fly licks the genitalia of a stationary female fly with his proboscis. An example of this is found in Drosophila melanogaster. GO:2000389 regulation of neutrophil extravasation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000389 Any process that modulates the frequency, rate or extent of neutrophil extravasation. GO:0016540 protein autoprocessing biolink:BiologicalProcess go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0016540 Processing which a protein carries out itself. This involves actions such as the autolytic removal of residues to generate the mature form of the protein. GO:0016541 obsolete intein biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016541 intein OBSOLETE. Intervening protein sequence excised from a protein precursor in protein splicing; inteins catalyze their own excision and many also possess endonuclease activity. GO:0016542 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016542 CHEBI:16098 4-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16098 CHEBI:16099 4'-O-beta-D-glucosyl-cis-p-coumaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16099 GO:2000380 regulation of mesoderm development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000380 Any process that modulates the frequency, rate or extent of mesoderm development. CHEBI:16096 palmatine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16096 GO:2000381 negative regulation of mesoderm development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000381 Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm development. CHEBI:16097 GDP-6-deoxy-alpha-D-talose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16097 CHEBI:16094 thiosulfate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16094 CHEBI:16095 sepiapterin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16095 CHEBI:16092 isoquinoline biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16092 CHEBI:16093 2-methylene-3-methylsuccinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16093 CHEBI:16091 dolichol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16091 GO:2000393 negative regulation of lamellipodium morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000393 negative regulation of lamellipodium organization Any process that stops, prevents or reduces the frequency, rate or extent of lamellipodium morphogenesis. GO:0016558 protein import into peroxisome matrix biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016558 protein transport to peroxisome matrix|peroxisome matrix protein import The import of proteins into the peroxisomal matrix. A peroxisome targeting signal (PTS) binds to a soluble receptor protein in the cytosol, and the resulting complex then binds to a receptor protein in the peroxisome membrane and is imported. The cargo protein is then released into the peroxisome matrix. GO:0016559 peroxisome fission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016559 peroxisome division|peroxisome proliferation The division of a mature peroxisome within a cell to form two or more separate peroxisome compartments. GO:2000394 positive regulation of lamellipodium morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000394 positive regulation of lamellipodium organization Any process that activates or increases the frequency, rate or extent of lamellipodium morphogenesis. GO:2000395 regulation of ubiquitin-dependent endocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000395 regulation of ubiquitin-mediated endocytosis Any process that modulates the frequency, rate or extent of ubiquitin-dependent endocytosis. GO:2000396 negative regulation of ubiquitin-dependent endocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000396 negative regulation of ubiquitin-mediated endocytosis Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin-dependent endocytosis. GO:2000397 positive regulation of ubiquitin-dependent endocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000397 positive regulation of ubiquitin-mediated endocytosis Any process that activates or increases the frequency, rate or extent of ubiquitin-dependent endocytosis. GO:0016554 cytidine to uridine editing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016554 The conversion of a cytosine residue to uridine in an RNA molecule by deamination. GO:2000398 regulation of thymocyte aggregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000398 regulation of immature T cell aggregation|regulation of thymic lymphocyte aggregation|regulation of T cell precursor aggregation|regulation of immature T-lymphocyte aggregation|regulation of immature T-cell aggregation Any process that modulates the frequency, rate or extent of thymocyte aggregation. GO:0016555 uridine to cytidine editing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016555 The conversion of a uridine residue to cytosine in an RNA molecule by amination. GO:2000399 negative regulation of thymocyte aggregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000399 negative regulation of immature T-lymphocyte aggregation|negative regulation of immature T-cell aggregation|negative regulation of T cell precursor aggregation|negative regulation of immature T cell aggregation|negative regulation of thymic lymphocyte aggregation Any process that stops, prevents or reduces the frequency, rate or extent of thymocyte aggregation. GO:0016556 mRNA modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016556 mRNA editing The covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically. GO:0016557 peroxisome membrane biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016557 The process in which a peroxisome membrane is synthesized, aggregates, and bonds together. GO:0016550 obsolete insertion or deletion editing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016550 insertion or deletion editing|insertion/deletion editing OBSOLETE. The insertion into or deletion from an RNA molecule of nucleotide residues not encoded in DNA; takes place during or after transcription. GO:0016551 obsolete posttranscriptional insertion or deletion editing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016551 posttranscriptional insertion or deletion editing|posttranscriptional insertion/deletion editing OBSOLETE. The insertion into or deletion from an RNA molecule of nucleotide residues not encoded in DNA; takes place after transcription. GO:0016552 obsolete cotranscriptional insertion or deletion editing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016552 cotranscriptional insertion/deletion editing|cotranscriptional insertion or deletion editing OBSOLETE. The insertion into or deletion from an RNA molecule of nucleotide residues not encoded in DNA; takes place during transcription. CHEBI:16089 6-deoxyerythronolide B biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16089 GO:0016553 base conversion or substitution editing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016553 base conversion/substitution editing Any base modification or substitution events that result in alterations in the coding potential or structural properties of RNAs as a result of changes in the base-pairing properties of the modified ribonucleoside(s). CHEBI:16087 isocitrate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16087 GO:2000390 negative regulation of neutrophil extravasation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000390 Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil extravasation. GO:2000391 positive regulation of neutrophil extravasation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000391 Any process that activates or increases the frequency, rate or extent of neutrophil extravasation. CHEBI:16085 UDP-alpha-D-galacturonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16085 GO:2000392 regulation of lamellipodium morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000392 regulation of lamellipodium organization Any process that modulates the frequency, rate or extent of lamellipodium morphogenesis. CHEBI:16086 mycothione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16086 GO:0016529 sarcoplasmic reticulum biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016529 Wikipedia:Endoplasmic_reticulum#Sarcoplasmic_reticulum A fine reticular network of membrane-limited elements that pervades the sarcoplasm of a muscle cell; continuous over large portions of the cell and with the nuclear envelope; that part of the endoplasmic reticulum specialized for calcium release, uptake and storage. GO:0016525 negative regulation of angiogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016525 down-regulation of angiogenesis|downregulation of angiogenesis|down regulation of angiogenesis|inhibition of angiogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis. GO:0016526 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016526 GO:0016527 obsolete brain-specific angiogenesis inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016527 brain-specific angiogenesis inhibitor activity OBSOLETE. (Was not defined before being made obsolete). GO:0016528 sarcoplasm biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016528 Wikipedia:Sarcoplasm The cytoplasm of a muscle cell; includes the sarcoplasmic reticulum. GO:0016521 pituitary adenylate cyclase activating polypeptide activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016521 pituitary adenylyl cyclase activating polypeptide activity The action characteristic of pituitary adenylate cyclase activating polypeptide, a peptide produced in the hypothalamus that binds to receptors to exert pleiotropic effects including control of neurotransmitter release, vasodilation, bronchodilation, activation of intestinal motility, increase in insulin and histamine secretion, immune modulation, and stimulation of cell proliferation and differentiation. GO:0016522 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016522 GO:0016523 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016523 GO:0016524 latrotoxin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016524 latrophilin Combining with alpha-latrotoxin, a potent presynaptic neurotoxin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0016520 growth hormone-releasing hormone receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016520 Combining with growth hormone-releasing hormone to initiate a change in cell activity. GO:0016536 obsolete cyclin-dependent protein kinase 5 activator regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016536 cyclin-dependent protein kinase 5 activator regulator activity|cyclin-dependent protein kinase 5 activator, intrinsic regulator activity OBSOLETE. Modulation of the activity of cyclin-dependent protein kinase 5 activator. GO:0016537 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016537 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016538 EC:2.7.1.-|Reactome:R-HSA-3215385 cyclin-dependent protein kinase regulator activity|cyclin|G1/S-specific cyclin|G2/M-specific cyclin|cyclin-dependent protein kinase, intrinsic regulator activity Modulates the activity of a cyclin-dependent protein serine/threonine kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins. GO:0016539 intein-mediated protein splicing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016539 intein The removal of an internal amino acid sequence (an intein) from a protein during protein maturation; the excision of inteins is precise and the N- and C-terminal exteins are joined by a normal peptide bond. Protein splicing involves 4 nucleophilic displacements by the 3 conserved splice junction residues. GO:0016532 superoxide dismutase copper chaperone activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016532 A copper chaperone activity that specifically delivers copper to the Cu-Zn superoxide dismutase, to activate superoxide dismutase activity. GO:0016533 protein kinase 5 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016533 cyclin-dependent protein kinase 5 holoenzyme complex A protein complex that has protein serine/threonine kinase activity; in mammals composed of catalytic subunit CDK5 and regulatory subunits CDK5R1 or CDK5R2. Contrary to its gene symbol, CDK5 is not cyclin-dependent. GO:0016534 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016534 GO:0016535 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016535 GO:0016530 metallochaperone activity biolink:MolecularActivity go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0016530 Directly binding to and delivering metal ions to a target protein. GO:0016531 copper chaperone activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016531 Directly binding to and delivering copper ions to a target protein. GO:0075049 obsolete modulation of symbiont cell wall strengthening involved in entry into host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075049 modulation of symbiont cell wall strengthening during entry into host OBSOLETE. Any process that modulates the frequency, rate or extent of symbiont cell wall strengthening during entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0099016 DNA end degradation evasion by virus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099016 VZ:3963 Any process, either active or passive, by which a virus evades and ends degradation of its DNA when free viral-DNA ends are exposed as part of its life-cycle. For example, some bacteriophages encode proteins that bind to free viral DNA ends, protecting them from degradation by host exonucleases. GO:0099017 maintenance of protein localization at cell tip biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099017 maintenance of protein location at cell tip Any process in which localization of a protein is maintained at the cell tip. GO:0099014 neuronal dense core vesicle organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099014 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuronal dense core vesicle. GO:0099015 degradation of host chromosome by virus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099015 VZ:3947 The catabolic breakdown of the DNA of a host chromosome by a virus. This occurs during infection of bacteria by some phages. It frees up a large pool of nucleoside 5'-triphophates for use in viral DNA synthesis. GO:0099012 neuronal dense core vesicle membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099012 The lipid bilayer surrounding a neuronal dense core vesicle. GO:0099013 neuronal dense core vesicle lumen biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099013 The volume enclosed by a neuronal dense core vesicle membrane. GO:0099010 modification of postsynaptic structure biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099010 synapse remodelling Any process that modifies the structure of a postsynapse. GO:0099011 neuronal dense core vesicle exocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099011 The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a neuronal dense core vesicle by fusion of the granule with the plasma membrane of a neuron in response to increased cytosolic calcium levels. GO:1905250 obsolete positive regulation of memory biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905250 enhancement of memory OBSOLETE. Any process that activates or increases the frequency, rate or extent of memory. GO:1905251 epidermal growth factor receptor signaling pathway involved in heart process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905251 epidermal growth factor receptor signaling pathway involved in cardiac process|EGFR signaling pathway involved in cardiac process|EGF receptor signalling pathway involved in cardiac process|EGF receptor signaling pathway involved in heart process|receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|epidermal growth factor receptor signalling pathway involved in heart process|ERBB1 signaling pathway involved in cardiac process|EGFR signaling pathway involved in heart process|EGF receptor signalling pathway involved in heart process|EGF receptor signaling pathway involved in cardiac process|receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|epidermal growth factor receptor signalling pathway involved in cardiac process|ERBB1 signaling pathway involved in heart process Any epidermal growth factor receptor signaling pathway that is involved in heart process. GO:1905252 obsolete regulation of epidermal growth factor receptor signaling pathway involved in heart process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905252 regulation of EGF receptor signaling pathway involved in cardiac process|regulation of EGF receptor signalling pathway involved in heart process|regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|regulation of EGFR signaling pathway involved in cardiac process|regulation of EGF receptor signaling pathway involved in heart process|regulation of EGF receptor signalling pathway involved in cardiac process|regulation of EGFR signaling pathway involved in heart process OBSOLETE. Any regulation of epidermal growth factor receptor signaling pathway that is involved in heart process. GO:1905253 obsolete negative regulation of epidermal growth factor receptor signaling pathway involved in heart process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905253 down regulation of epidermal growth factor receptor signaling pathway involved in heart process|inhibition of epidermal growth factor receptor signaling pathway involved in heart process|negative regulation of EGF receptor signalling pathway involved in cardiac process|down-regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|negative regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|negative regulation of EGFR signaling pathway involved in cardiac process|negative regulation of EGF receptor signaling pathway involved in heart process|downregulation of epidermal growth factor receptor signaling pathway involved in cardiac process|down regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|negative regulation of EGF receptor signalling pathway involved in heart process|down-regulation of epidermal growth factor receptor signaling pathway involved in heart process|negative regulation of EGFR signaling pathway involved in heart process|inhibition of epidermal growth factor receptor signaling pathway involved in cardiac process|negative regulation of EGF receptor signaling pathway involved in cardiac process|downregulation of epidermal growth factor receptor signaling pathway involved in heart process OBSOLETE. Any negative regulation of epidermal growth factor receptor signaling pathway that is involved in heart process. GO:1905254 obsolete positive regulation of epidermal growth factor receptor signaling pathway involved in heart process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905254 activation of epidermal growth factor receptor signaling pathway involved in cardiac process|upregulation of epidermal growth factor receptor signaling pathway involved in heart process|positive regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|positive regulation of EGFR signaling pathway involved in cardiac process|up regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|stimulation of epidermal growth factor receptor signaling pathway involved in heart process|up-regulation of epidermal growth factor receptor signaling pathway involved in heart process|activation of epidermal growth factor receptor signaling pathway involved in heart process|positive regulation of EGF receptor signalling pathway involved in heart process|positive regulation of EGF receptor signaling pathway involved in heart process|upregulation of epidermal growth factor receptor signaling pathway involved in cardiac process|positive regulation of EGFR signaling pathway involved in heart process|up regulation of epidermal growth factor receptor signaling pathway involved in heart process|up-regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|positive regulation of EGF receptor signalling pathway involved in cardiac process|positive regulation of EGF receptor signaling pathway involved in cardiac process|stimulation of epidermal growth factor receptor signaling pathway involved in cardiac process OBSOLETE. Any positive regulation of epidermal growth factor receptor signaling pathway that is involved in heart process. GO:1905255 regulation of RNA binding transcription factor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905255 regulation of transcription factor activity Any process that modulates the frequency, rate or extent of RNA binding transcription factor activity. GO:1905256 negative regulation of RNA binding transcription factor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905256 inhibition of RNA binding transcription factor activity|down regulation of RNA binding transcription factor activity|downregulation of RNA binding transcription factor activity|down-regulation of RNA binding transcription factor activity Any process that stops, prevents or reduces the frequency, rate or extent of RNA binding transcription factor activity. GO:1905246 negative regulation of aspartic-type peptidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905246 down-regulation of aspartic-type peptidase activity|downregulation of aspartic-type peptidase activity|down regulation of aspartic-type peptidase activity|inhibition of aspartic-type peptidase activity|pepsin inhibitor Any process that stops, prevents or reduces the frequency, rate or extent of aspartic-type peptidase activity. GO:1905247 positive regulation of aspartic-type peptidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905247 up regulation of aspartic-type peptidase activity|upregulation of aspartic-type peptidase activity|up-regulation of aspartic-type peptidase activity|activation of aspartic-type peptidase activity Any process that activates or increases the frequency, rate or extent of aspartic-type peptidase activity. GO:0090688 cleavage furrow rim biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090688 The part of the cleavage furrow closest to the cell surface. GO:1905248 obsolete regulation of memory biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905248 modulation of memory OBSOLETE. Any process that modulates the frequency, rate or extent of memory. GO:0090689 cleavage furrow leading edge biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090689 The 'trough' of the cleavage furrow. This is the part of the cleavage furrow closest to the contractile ring. GO:1905249 obsolete negative regulation of memory biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905249 inhibition of memory|suppression of memory OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of memory. GO:0051070 galactomannan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051070 galactomannan anabolism|galactomannan synthesis|galactomannan formation|galactomannan biosynthesis The chemical reactions and pathways resulting in the formation of galactomannan, a polysaccharide composed of D-galactosyl and D-mannosyl. The mannosyl units form the backbone structure (a linear main chain) with the D-galactosyl as single side units. GO:0051071 4,6-pyruvylated galactose residue metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051071 PvGal metabolic process|4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3 metabolic process|4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3 metabolism|4,6-pyruvylated galactose residue metabolism|PvGal metabolism The chemical reactions and pathways involving the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3-. The galactose residue is part of a larger polysaccharide chain. GO:0075040 regulation of establishment of turgor in appressorium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075040 regulation of turgor formation in appressorium Any process modulates the frequency, rate or extent of turgor formation in the symbiont appressorium. GO:0090682 GPCR bitter taste receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090682 G protein-coupled receptor bitter taste receptor activity|G-protein coupled receptor bitter taste receptor activity A G protein-coupled receptor activity that is responsible for the sense of bitter taste. GO:0051074 obsolete protein tetramerization activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051074 protein tetramerization activity OBSOLETE. The formation of a protein tetramer, a macromolecular structure consisting of four noncovalently associated identical or nonidentical subunits. GO:0075041 positive regulation of establishment of turgor in appressorium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075041 Any process that activates or increases the frequency, rate or extent of turgor formation in the symbiont appressorium. GO:0090683 GPCR sweet taste receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090683 G-protein coupled receptor sweet taste receptor activity A G protein-coupled receptor activity that is responsible for the sense of sweet taste. GO:0075042 negative regulation of establishment of turgor in appressorium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075042 Any process that stops, prevents, or reduces the frequency, rate or extent of turgor formation in the symbiont appressorium. GO:0051075 S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051075 S-adenosyl methionine:tRNA ribosyltransferase-isomerase activity Catalysis of the reaction: S-adenosylmethionine + 7-(aminomethyl)-7-deazaguanosine-tRNA = adenine + methionine + epoxyqueuosine-tRNA. 7-(aminomethyl)-7-deazaguanosine-tRNA is also known as preQ1-tRNA, and epoxyqueuosine-tRNA as oQ-tRNA. GO:0090680 disruption by virus of host outer membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090680 A process by which a virus has a negative effect on the functioning of a host outer membrane. GO:0051072 4,6-pyruvylated galactose residue biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051072 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3 biosynthetic process|4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3 biosynthesis|4,6-pyruvylated galactose residue anabolism|4,6-pyruvylated galactose residue synthesis|PvGal biosynthetic process|4,6-pyruvylated galactose residue biosynthesis|PvGal biosynthesis|4,6-pyruvylated galactose residue formation The chemical reactions and pathways resulting in the formation of the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3-. The galactose residue is part of a larger polysaccharide chain. GO:0075043 melanization of appressorium wall biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075043 maintenance of turgor in appressorium by melanization|melanization of appressorium to maintain turgor pressure The process in which melanin is produced in the appressorium of the symbiont. Melanization of the appressorium increases turgor pressure in the appressorium. GO:0090681 GPCR taste receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090681 G-protein-coupled taste receptor activity|G-protein coupled taste receptor activity A G protein-coupled receptor activity that is responsible for the sense of taste. GO:0075044 positive regulation by symbiont of host autophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075044 positive regulation by symbiont of host autophagotic process|autophagy of host cells involved in interaction with symbiont|autophagy of host cells during interaction with symbiont Any process in which a symbiont organism increases the frequency, rate or extent of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051073 adenosylcobinamide-GDP ribazoletransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051073 EC:2.7.8.26|RHEA:16049|MetaCyc:COBALAMINSYN-RXN adenosylcobinamide-GDP:alpha-ribazole ribazoletransferase activity|cobalamin synthase activity|cobalamin (5'-phosphate) synthase activity|CobS|cobalamin-5'-phosphate synthase activity Catalysis of the reaction: adenosylcobinamide-GDP + alpha-ribazole = GMP + adenosylcobalamin. GO:0090686 glycine betaine-activated nonselective monovalent cation channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090686 Enables the transmembrane transfer of a monovalent cation by a channel that opens when glycine betaine has been bound by the channel complex or one of its constituent parts. GO:0051078 meiotic nuclear envelope disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051078 meiotic nuclear envelope catabolism|meiotic nuclear envelope degradation|meiotic nuclear envelope breakdown The cell cycle process in which the controlled breakdown of the nuclear envelope during meiotic cell division occurs. GO:0075045 regulation of formation by symbiont of haustorium for nutrient acquisition from host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075045 Any process that modulates the frequency, rate or extent of symbiont haustorium formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0090687 activation of meiosis I spindle assembly checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090687 Any process that starts the inactive process of a meiosis I cell cycle spindle assembly checkpoint. GO:0051079 meiosis I nuclear envelope disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051079 meiosis I nuclear envelope catabolism|meiosis I nuclear envelope degradation|meiosis I nuclear envelope breakdown The controlled breakdown of the nuclear envelope during the first division of meiosis. GO:0075046 positive regulation of formation by symbiont of haustorium for nutrient acquisition from host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075046 Any process that activates or increases the frequency, rate or extent of symbiont haustorium formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075047 negative regulation of formation by symbiont of haustorium for nutrient acquisition from host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075047 Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont haustorium formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0099018 restriction-modification system evasion by virus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099018 VZ:3966 Any process, either active or passive, by which a virus evades the DNA restriction modification system of its host. Some viruses encode their own methyltransferase in order to protect their genome from host restriction enzymes. Others directly inhibit restruction enzymes while some use unusual bases in their genome to avoid restriction. GO:0090684 contact chemoreceptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090684 contact chemosensation receptor activity A non-GPCR transmembrane signaling receptor activity that is responsible for contact chemoreception. GO:0051076 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051076 GO:0090685 RNA localization to nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090685 RNA localisation to nucleus A macromolecular localization process in which RNA is transported to and maintained in a location within the nucleus. GO:0099019 maintenance of protein localization at growing cell tip biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099019 maintenance of protein location at growing cell tip Any process in which localization of a protein is maintained at the growing cell tip. GO:0051077 secondary cell septum biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0051077 secondary septum Cell wall structures composed of linear polysaccharides which are deposited at both sides of the primary septum at 90 degrees to the primary septum. GO:0075048 obsolete cell wall strengthening in symbiont involved in entry into host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075048 cell wall thickening in symbiont during entry into host|cell wall strengthening in symbiont during entry into host|symbiont cell wall strengthening during entry into host OBSOLETE. A process in which the cell wall of the symbiont is strengthened or thickened during penetration into the body, tissues, or cells of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0099027 anchored component of presynaptic endocytic zone membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099027 The component of the presynaptic endocytic zone membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. GO:0075038 negative regulation of appressorium maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075038 negative regulation of appressorium maturation on or near host|negative regulation of maturation of appressorium on or near host Any process that stops, prevents, or reduces the frequency, rate or extent symbiont appressorium maturation. GO:0075039 establishment of turgor in appressorium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075039 formation of turgor in appressorium|establishment of turgor in symbiont appressorium on or near host|generation of turgor in appressorium The process in which hydrostatic pressure is increased within the symbiont appressorium to breach the cuticle of the host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0099028 anchored component of postynaptic endocytic zone membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099028 The component of the postynaptic endocytic zone membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. GO:0099025 anchored component of postsynaptic membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099025 The component of the postsynaptic membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. GO:0099026 anchored component of presynaptic membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099026 anchored component of presynaptic plasma membrane The component of the presynaptic membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. GO:0099023 vesicle tethering complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0099023 Any protein complex that plays a role in vesicle tethering. GO:0099024 plasma membrane invagination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099024 An infolding of the plasma membrane. GO:0090690 obsolete heteroreceptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090690 OBSOLETE. A receptor complex that consists of two or more different receptor complexes that individually undergo combination with a hormone, neurotransmitter, drug or intracellular messenger. The formation of the higher level complex initiates a change in cell function. GO:0099021 cortical endoplasmic reticulum lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0099021 The volume enclosed by the membranes of the cortical endoplasmic reticulum. GO:0099022 vesicle tethering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099022 The initial, indirect interaction between a vesicle membrane and a membrane to which it is targeted for fusion. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to interaction between factors involved in fusion. GO:1905260 positive regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905260 up regulation of intrinsic apoptotic signaling pathway in response to nitrosative stress|activation of intrinsic apoptotic signaling pathway in response to nitrosative stress|up-regulation of nitrosative stress-induced apoptosis|positive regulation of intrinsic apoptotic signaling pathway in response to nitrosative stress|up-regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway|activation of nitrosative stress-induced intrinsic apoptotic signaling pathway|activation of nitrosative stress-induced apoptosis|up-regulation of intrinsic apoptotic signaling pathway in response to nitrosative stress|positive regulation of nitrosative stress-induced apoptosis|up regulation of nitrosative stress-induced apoptosis|positive regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway|up regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway|upregulation of intrinsic apoptotic signaling pathway in response to nitrosative stress|upregulation of nitrosative stress-induced apoptosis|upregulation of nitrosative stress-induced intrinsic apoptotic signaling pathway Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to nitrosative stress. GO:0099020 perinuclear endoplasmic reticulum lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0099020 The volume enclosed by the membranes of the perinuclear endoplasmic reticulum. GO:1905261 regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905261 Any process that modulates the frequency, rate or extent of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination. GO:1905262 negative regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905262 downregulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination|down regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination|inhibition of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination|down-regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination Any process that stops, prevents or reduces the frequency, rate or extent of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination. GO:1905263 positive regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905263 upregulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination|up-regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination|activation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination|up regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination Any process that activates or increases the frequency, rate or extent of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination. GO:1905264 blasticidin S metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905264 blasticidin S metabolism The chemical reactions and pathways involving blasticidin S. GO:1905265 blasticidin S catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905265 blasticidin S breakdown|blasticidin S degradation|blasticidin S catabolism The chemical reactions and pathways resulting in the breakdown of blasticidin S. GO:1905266 blasticidin S biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905266 blasticidin S anabolism|blasticidin S synthesis|blasticidin S formation|blasticidin S biosynthesis The chemical reactions and pathways resulting in the formation of blasticidin S. GO:1905267 endonucleolytic cleavage involved in tRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905267 RNA phosphodiester bond hydrolysis, endonucleolytic involved in tRNA maturation Any endonucleolytic RNA phosphodiester bond hydrolysis that is involved in tRNA processing. GO:1905257 positive regulation of RNA binding transcription factor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905257 up-regulation of RNA binding transcription factor activity|upregulation of RNA binding transcription factor activity|up regulation of RNA binding transcription factor activity|activation of RNA binding transcription factor activity Any process that activates or increases the frequency, rate or extent of RNA binding transcription factor activity. GO:1905258 regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905258 regulation of nitrosative stress-induced apoptosis|regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway|regulation of intrinsic apoptotic signaling pathway in response to nitrosative stress Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to nitrosative stress. GO:1905259 negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905259 negative regulation of intrinsic apoptotic signaling pathway in response to nitrosative stress|down-regulation of nitrosative stress-induced apoptosis|negative regulation of nitrosative stress-induced apoptosis|down-regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway|negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway|inhibition of intrinsic apoptotic signaling pathway in response to nitrosative stress|downregulation of nitrosative stress-induced apoptosis|downregulation of nitrosative stress-induced intrinsic apoptotic signaling pathway|down regulation of nitrosative stress-induced apoptosis|down regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway|down regulation of intrinsic apoptotic signaling pathway in response to nitrosative stress|inhibition of nitrosative stress-induced intrinsic apoptotic signaling pathway|downregulation of intrinsic apoptotic signaling pathway in response to nitrosative stress|inhibition of nitrosative stress-induced apoptosis|down-regulation of intrinsic apoptotic signaling pathway in response to nitrosative stress Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to nitrosative stress. GO:0090699 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090699 GO:0051081 nuclear envelope disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051081 nuclear envelope degradation|nuclear envelope breakdown|nuclear envelope catabolism The controlled breakdown of the nuclear envelope in the context of a normal process. GO:0051082 unfolded protein binding biolink:MolecularActivity go-plus goslim_generic|goslim_chembl|goslim_yeast|goslim_drosophila http://purl.obolibrary.org/obo/GO_0051082 Reactome:R-HSA-9694337|Reactome:R-HSA-9683772 binding unfolded ER proteins|fimbrium-specific chaperone activity|ribosomal chaperone activity|histone-specific chaperone activity|glycoprotein-specific chaperone activity|tubulin-specific chaperone activity|chaperone activity Interacting selectively and non-covalently with an unfolded protein. GO:0051080 meiosis II nuclear envelope disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051080 meiosis II nuclear envelope degradation|meiosis II nuclear envelope breakdown|meiosis II nuclear envelope catabolism The controlled breakdown of the nuclear envelope during the second division of meiosis. GO:0051085 chaperone cofactor-dependent protein refolding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051085 chaperone cofactor-dependent 'de novo' protein folding|chaperone co-factor-dependent protein refolding|chaperone cofactor-dependent protein folding|chaperone co-factor-dependent protein folding|chaperone mediated protein folding requiring cofactor The process of assisting in the correct posttranslational noncovalent assembly of proteins, which is dependent on additional protein cofactors. This process occurs over one or several cycles of nucleotide hydrolysis-dependent binding and release. GO:0075030 modulation of formation of symbiont germ tube hook structure for appressorium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075030 modulation of symbiont germ tube hook structure formation on or near host|modulation of germ tube tip of symbiont on or near the exterior of host|regulation of formation of symbiont germ tube hook structure on or near host Any process that modulates the frequency, rate or extent of symbiont germ tube hook structure formation. GO:0090693 plant organ senescence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090693 The process that occurs in a plant organ near the end of its active life that is associated with the dismantling of cell components and membranes, and an overall decline in metabolism. GO:0075031 positive regulation of formation of symbiont germ tube hook structure for appressorium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075031 positive regulation of germ tube tip of symbiont on or near the exterior of host|positive regulation of formation of symbiont germ tube hook structure on or near host|positive regulation of symbiont germ tube hook structure formation on or near host Any process that activates, maintains or increases the frequency, rate or extent of symbiont germ tube hook structure formation. GO:0051086 chaperone mediated protein folding independent of cofactor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051086 chaperone cofactor-independent protein folding The process of assisting in the correct noncovalent assembly of posttranslational proteins and does not depend on additional protein cofactors. This function occurs over one or more cycles of nucleotide-dependent binding and release. GO:0090694 Scc2-Scc4 cohesin loading complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090694 Mis4-Ssl3 cohesin loading complex A eukaryotically conserved heterodimeric protein complex (comprising adherin and the chromatid cohesion factor MAU2/Scc4/Ssl3) required for the loading of a cohesin, complex onto DNA. GO:0075032 negative regulation of formation of symbiont germ tube hook structure for appressorium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075032 negative regulation of symbiont germ tube hook structure formation on or near host|negative regulation of germ tube tip of symbiont on or near the exterior of host|negative regulation of formation of symbiont germ tube hook structure on or near host Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont germ tube hook structure formation. GO:0090691 formation of plant organ boundary biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090691 The regionalization process that specifies plant organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues. GO:0051083 'de novo' cotranslational protein folding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051083 nascent polypeptide association|'de novo' co-translational protein folding|multidomain protein assembly The process of assisting in the correct noncovalent assembly of the ribosome-bound nascent chains of a multidomain protein whilst other parts of the protein are still being translated. GO:0051084 'de novo' posttranslational protein folding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051084 'de novo' post-translational protein folding The process of assisting in the correct noncovalent folding of newly formed polypeptides or folding intermediates of polypeptides that have exited the ribosome and/or have been stabilized and transferred by other chaperone proteins. This process could involve several cycles of ATP hydrolysis. GO:0090692 mitochondrial membrane scission site biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090692 The site on the mitochondrial membrane where the separation of a single continuous mitochondrial membrane into two membranes occurs as a final step in mitochondrial fission. GO:0075033 appressorium septum formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075033 septum formation involved in appressorium formation on or near host|septum formation involved in appressorium formation|septum formation during appressorium formation on or near host The process in which a symbiont partition is formed to separate the appressorium from the germination tube, occurring during appressorium formation. GO:0090697 post-embryonic plant organ morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090697 Morphogenesis, during the post-embryonic phase, of a plant tissue or tissues that work together to perform a specific function or functions. Morphogenesis pertains to process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. GO:0075034 nuclear division involved in appressorium formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075034 nuclear division during appressorium formation on or near host|nuclear division involved in appressorium formation on or near host The process in which nuclear division occurs within a symbiont spore that contributes to appressorium formation. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051089 constitutive protein ectodomain proteolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051089 The proteolytic cleavage of transmembrane proteins and release of their ectodomain that occurs constantly, regardless of environmental conditions or demands. GO:0090698 post-embryonic plant morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090698 The process, occurring after plant embryonic development, by which anatomical structures are generated and organized. GO:0075035 appressorium maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075035 appressorium maturation on or near host|maturation of appressorium on or near host|maturation of symbiont appressorium on or near host The process in which specialized features of the symbiont appressorium are acquired post initiation, to aid in infection of the host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075036 regulation of appressorium maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075036 regulation of appressorium maturation on or near host|regulation of maturation of appressorium on or near host Any process that modulates the frequency, rate or extent of symbiont appressorium maturation. GO:0051087 chaperone binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051087 co-chaperone activity|co-chaperonin activity|chaperone protein binding Interacting selectively and non-covalently with a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport. GO:0099029 anchored component of presynaptic active zone membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099029 The component of the presynaptic active zone membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. GO:0090695 Wpl/Pds5 cohesin loading/unloading complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090695 A eukaryotically conserved heterodimeric protein complex (comprising Wings apart-like protein and the Pds5 Armadillo repeat cohesin associated protein) involved in the loading and unloading of a cohesin complex onto DNA. GO:0075037 positive regulation of appressorium maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075037 positive regulation of appressorium maturation on or near host|positive regulation maturation of appressorium on or near host Any process that activates or increases the frequency, rate or extent of symbiont appressorium maturation. GO:0090696 post-embryonic plant organ development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090696 Development, taking place during the post-embryonic phase of a plant tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. GO:0051088 obsolete PMA-inducible membrane protein ectodomain proteolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051088 OBSOLETE. The proteolytic cleavage of transmembrane proteins and release of their ectodomain that occurs after induction by phorbol-12-myristate-13-acetate (PMA), a protein kinase C agonist. GO:1905270 Meynert cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905270 The process in which a relatively unspecialized cell acquires the specialized features of a Meynert cell. GO:1905271 regulation of proton-transporting ATP synthase activity, rotational mechanism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905271 regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism|regulation of hydrogen ion translocating F-type ATPase activity|regulation of H+-transporting ATP synthase activity|regulation of hydrogen ion transporting two-sector ATPase activity Any process that modulates the frequency, rate or extent of proton-transporting ATP synthase activity, rotational mechanism. GO:1905272 negative regulation of proton-transporting ATP synthase activity, rotational mechanism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905272 down-regulation of proton-transporting ATP synthase activity, rotational mechanism|down-regulation of hydrogen ion transporting two-sector ATPase activity|negative regulation of hydrogen ion transporting two-sector ATPase activity|down regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism|down regulation of hydrogen ion translocating F-type ATPase activity|down regulation of H+-transporting ATP synthase activity|downregulation of hydrogen ion transporting ATP synthase activity, rotational mechanism|inhibition of proton-transporting ATP synthase activity, rotational mechanism|downregulation of hydrogen ion translocating F-type ATPase activity|downregulation of hydrogen ion transporting two-sector ATPase activity|downregulation of H+-transporting ATP synthase activity|down regulation of hydrogen ion transporting two-sector ATPase activity|inhibition of hydrogen ion transporting two-sector ATPase activity|down-regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism|negative regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism|down-regulation of hydrogen ion translocating F-type ATPase activity|negative regulation of hydrogen ion translocating F-type ATPase activity|down-regulation of H+-transporting ATP synthase activity|down regulation of proton-transporting ATP synthase activity, rotational mechanism|negative regulation of H+-transporting ATP synthase activity|inhibition of hydrogen ion transporting ATP synthase activity, rotational mechanism|inhibition of hydrogen ion translocating F-type ATPase activity|downregulation of proton-transporting ATP synthase activity, rotational mechanism|inhibition of H+-transporting ATP synthase activity Any process that stops, prevents or reduces the frequency, rate or extent of proton-transporting ATP synthase activity, rotational mechanism. GO:1905273 positive regulation of proton-transporting ATP synthase activity, rotational mechanism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905273 activation of hydrogen ion transporting two-sector ATPase activity|up-regulation of H+-transporting ATP synthase activity|up regulation of proton-transporting ATP synthase activity, rotational mechanism|activation of proton-transporting ATP synthase activity, rotational mechanism|upregulation of hydrogen ion transporting ATP synthase activity, rotational mechanism|upregulation of hydrogen ion translocating F-type ATPase activity|upregulation of H+-transporting ATP synthase activity|positive regulation of hydrogen ion transporting two-sector ATPase activity|up regulation of hydrogen ion transporting two-sector ATPase activity|up-regulation of proton-transporting ATP synthase activity, rotational mechanism|up regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism|up regulation of hydrogen ion translocating F-type ATPase activity|activation of hydrogen ion transporting ATP synthase activity, rotational mechanism|positive regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism|activation of hydrogen ion translocating F-type ATPase activity|positive regulation of hydrogen ion translocating F-type ATPase activity|up regulation of H+-transporting ATP synthase activity|activation of H+-transporting ATP synthase activity|positive regulation of H+-transporting ATP synthase activity|upregulation of hydrogen ion transporting two-sector ATPase activity|upregulation of proton-transporting ATP synthase activity, rotational mechanism|up-regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism|up-regulation of hydrogen ion translocating F-type ATPase activity|up-regulation of hydrogen ion transporting two-sector ATPase activity Any process that activates or increases the frequency, rate or extent of proton-transporting ATP synthase activity, rotational mechanism. GO:1905274 regulation of modification of postsynaptic actin cytoskeleton biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_1905274 regulation of postsynaptic actin cytoskeleton remodelling Any process that modulates the frequency, rate or extent of modification of postsynaptic actin cytoskeleton. GO:1905275 Rohon-Beard neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905275 The process in which a relatively unspecialized cell acquires the specialized features of a Rohon-Beard neuron. GO:1905276 regulation of epithelial tube formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905276 Any process that modulates the frequency, rate or extent of epithelial tube formation. GO:1905277 negative regulation of epithelial tube formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905277 inhibition of epithelial tube formation|down regulation of epithelial tube formation|downregulation of epithelial tube formation|down-regulation of epithelial tube formation Any process that stops, prevents or reduces the frequency, rate or extent of epithelial tube formation. GO:1905278 positive regulation of epithelial tube formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905278 up-regulation of epithelial tube formation|upregulation of epithelial tube formation|up regulation of epithelial tube formation|activation of epithelial tube formation Any process that activates or increases the frequency, rate or extent of epithelial tube formation. GO:1905268 negative regulation of chromatin organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905268 inhibition of establishment or maintenance of chromatin architecture|inhibition of chromatin organisation|downregulation of chromatin organization|negative regulation of chromatin modification|down regulation of chromatin organization|inhibition of chromatin organization|down-regulation of establishment or maintenance of chromatin architecture|negative regulation of establishment or maintenance of chromatin architecture|down-regulation of chromatin organisation|negative regulation of chromatin organisation|down-regulation of chromatin organization|downregulation of establishment or maintenance of chromatin architecture|downregulation of chromatin organisation|down regulation of establishment or maintenance of chromatin architecture|down regulation of chromatin organisation Any process that stops, prevents or reduces the frequency, rate or extent of chromatin organization. GO:0090668 endothelial cell chemotaxis to vascular endothelial growth factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090668 The directed movement of an endothelial cell in response to the presence of vascular endothelial growth factor (VEGF). GO:1905269 positive regulation of chromatin organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905269 up regulation of chromatin organization|upregulation of establishment or maintenance of chromatin architecture|upregulation of chromatin organisation|upregulation of chromatin organization|positive regulation of chromatin modification|activation of establishment or maintenance of chromatin architecture|up-regulation of establishment or maintenance of chromatin architecture|up-regulation of chromatin organisation|activation of chromatin organisation|activation of chromatin organization|up-regulation of chromatin organization|positive regulation of establishment or maintenance of chromatin architecture|positive regulation of chromatin organisation|up regulation of establishment or maintenance of chromatin architecture|up regulation of chromatin organisation Any process that activates or increases the frequency, rate or extent of chromatin organization. GO:0090669 telomerase RNA stabilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090669 TERC stabilization Prevention of degradation of telomerase RNA (TERC) molecules. GO:0090666 scaRNA localization to Cajal body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090666 A process in which a small Cajal body-specific RNA is transported to, or maintained in, a Cajal body. GO:0090667 cell chemotaxis to vascular endothelial growth factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090667 The directed movement of a motile cell in response to the presence of vascular endothelial growth factor (VEGF). GO:0051092 positive regulation of NF-kappaB transcription factor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051092 activation of NF-kappaB|NF-kappaB activation|activation of NF-kappaB transcription factor Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB. GO:0051093 negative regulation of developmental process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051093 inhibition of developmental process|down regulation of developmental process|downregulation of developmental process|down-regulation of developmental process Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). GO:0075060 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075060 GO:0051090 regulation of DNA-binding transcription factor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051090 regulation of androgen receptor activity|regulation of thyroid hormone receptor activity|regulation of transcription factor activity|regulation of DNA binding transcription factor activity|regulation of sequence-specific DNA binding transcription factor activity Any process that modulates the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription. GO:0075061 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075061 GO:0051091 positive regulation of DNA-binding transcription factor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051091 up-regulation of transcription factor activity|upregulation of transcription factor activity|positive regulation of thyroid hormone receptor activity|up regulation of transcription factor activity|activation of transcription factor activity|positive regulation of transcription factor activity|stimulation of transcription factor activity|positive regulation of DNA binding transcription factor activity|positive regulation of sequence-specific DNA binding transcription factor activity Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription. GO:0075062 obsolete regulation of invasive hypha growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075062 regulation of symbiont invasive hypha formation within host|regulation of symbiont invasive hypha formation in host OBSOLETE. Any process that modulates the frequency, rate or extent of symbiont invasive hypha formation within host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0090660 cerebrospinal fluid circulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090660 CSF circulation|CSF flow|cerebrospinal fluid flow The neurological system process driven by motile cilia on ependymal cells of the brain by which cerebrospinal fluid circulates from the sites of secretion to the sites of absorption. In ventricular cavities, the flow is unidirectional and rostrocaudal, in subarachnoid spaces, the flow is multi-directional. GO:0075063 obsolete positive regulation of invasive hypha growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075063 positive regulation of symbiont invasive hypha formation in host|positive regulation of symbiont invasive hypha formation within host OBSOLETE. Any process that activates, maintains or increases the frequency, rate or extent of symbiont invasive hypha formation within host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051096 positive regulation of helicase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051096 up regulation of helicase activity|activation of helicase activity|stimulation of helicase activity|up-regulation of helicase activity|upregulation of helicase activity Any process that activates or increases the activity of a helicase. GO:0051097 negative regulation of helicase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051097 down regulation of helicase activity|downregulation of helicase activity|down-regulation of helicase activity|inhibition of helicase activity Any process that stops or reduces the activity of a helicase. GO:0090661 box H/ACA telomerase RNP complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090661 A box H/ACA ribonucleoprotein complex that contains the RNA component of vertebrate telomerase, the enzyme essential for the replication of chromosome termini in most eukaryotes. This ribonucleoprotein complex is a structural box H/ACA RNP, which does not have the catalytic pseudouridylation function shared by the majority of H/ACA RNPs present in the cell. GO:0075064 obsolete negative regulation invasive hypha growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075064 negative regulation of symbiont invasive hypha formation in host|negative regulation of symbiont invasive hypha formation within host OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont invasive hypha formation within host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051094 positive regulation of developmental process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051094 up-regulation of developmental process|upregulation of developmental process|up regulation of developmental process|activation of developmental process|stimulation of developmental process Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). GO:0075065 obsolete growth or development of symbiont in host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075065 growth or development of symbiont in host cell OBSOLETE. The increase in size or mass of symbiont, or the progression of the symbiont from an initial condition to a later condition, occurring in its host's cell. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051095 regulation of helicase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051095 Any process that modulates the frequency, rate or extent of helicase activity. GO:0075066 obsolete growth or development of symbiont in host organelle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075066 growth or development of symbiont in host organelle OBSOLETE. The increase in size or mass of symbiont, or the progression of the symbiont from an initial condition to a later condition, occurring in its host's organelle. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0090664 response to high population density biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090664 response to crowding Any process that results in a change in state or activity of a cell or a multicellular organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a higher than normal number of multicellular organisms living per unit area. GO:0075067 obsolete growth or development of symbiont in host intercellular space biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075067 growth or development of symbiont in host intercellular space OBSOLETE. The increase in size or mass of symbiont, or the progression of the symbiont from an initial condition to a later condition, occurring in its host's intercellular space. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0090665 glycoprotein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090665 A protein complex containing at least one glycosylated protein, may be held together by both covalent and noncovalent bonds. GO:0075068 obsolete growth or development of symbiont in host vascular tissue biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075068 growth or development of symbiont in host vascular tissue OBSOLETE. The increase in size or mass of symbiont, or the progression of the symbiont from an initial condition to a later condition, occurring in its host's vascular tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075069 adhesion of symbiont infection cushion to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075069 adhesion of symbiont infection cushion to host during symbiotic interaction The attachment of an infection cushion of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051098 regulation of binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051098 Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule. GO:0090662 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090662 GO:0090663 galanin-activated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090663 galanin signaling pathway|galanin-activated signalling pathway|galanin signalling pathway The series of molecular signals generated as a consequence of the peptide neurotransmitter galanin binding to a cell surface receptor. GO:0051099 positive regulation of binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051099 up regulation of binding|activation of binding|stimulation of binding|up-regulation of binding|upregulation of binding Any process that activates or increases the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule. GO:0099005 extrinsic component of postsynaptic recycling endosome membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099005 The component of the postsynaptic recycling endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:0099006 viral entry via permeabilization of endosomal membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099006 VZ:985 viral penetration via permeabilization of host membrane The entry of a non-enveloped virus into a host eukaryotic cell, following endocytosis, via permeabilization of the endosomal membrane by membrane penetration protein(s) associated with the viral capsid. In some cases, viral membrane-penetration protein require first to be activated to display its membrane penetrating activity. Activation can be due to receptor binding or the acidic pH of the endosomal lumen. GO:0099003 vesicle-mediated transport in synapse biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099003 Any vesicle-mediated transport that occurs in a synapse. GO:0099004 calmodulin dependent kinase signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099004 CAMK signaling pathway Any signal transduction pathway involving calmodulin dependent kinase activity. GO:0099001 viral genome ejection through host cell envelope, long flexible tail mechanism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099001 VZ:3952 viral long flexible tail ejection system Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm via a long, flexible tail ejection system consisting a baseplate, a central tube and a terminator complex which attaches the tail to the phage capsid. Upon binding to the host cell surface, the baseplate changes its conformation and triggers genome ejection into the host cell cytoplasm. GO:0099002 viral genome ejection through host cell envelope, short tail mechanism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099002 VZ:3954 viral short tail ejection system Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm via a short tail ejection system consisting a central tube, the connector which attaches the tail to the phage capsid and releases inner core proteins. Upon binding to the host cell surface, the phage displays a tube-like extension of its short tail that penetrates both host membranes. This tail extension comes from the release of viral core proteins with channel forming properties. GO:1905280 negative regulation of retrograde transport, endosome to Golgi biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905280 inhibition of retrograde transport, endosome to Golgi|down-regulation of retrograde (endosome to Golgi) transport|negative regulation of retrograde (endosome to Golgi) transport|down regulation of retrograde transport, endosome to Golgi|downregulation of retrograde (endosome to Golgi) transport|downregulation of retrograde transport, endosome to Golgi|down regulation of retrograde (endosome to Golgi) transport|inhibition of retrograde (endosome to Golgi) transport|down-regulation of retrograde transport, endosome to Golgi Any process that stops, prevents or reduces the frequency, rate or extent of retrograde transport, endosome to Golgi. GO:0099000 viral genome ejection through host cell envelope, contractile tail mechanism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099000 VZ:3950 viral contractile tail ejection system Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm via a contractile tail ejection system consisting of a baseplate, a central tube and an external contractile sheath. Upon binding to the host cell surface, the baseplate changes its conformation and triggers sheath contraction, driving the rigid internal tail tube through the cell envelope. GO:1905281 positive regulation of retrograde transport, endosome to Golgi biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905281 up-regulation of retrograde (endosome to Golgi) transport|activation of retrograde (endosome to Golgi) transport|up-regulation of retrograde transport, endosome to Golgi|upregulation of retrograde transport, endosome to Golgi|positive regulation of retrograde (endosome to Golgi) transport|up regulation of retrograde (endosome to Golgi) transport|up regulation of retrograde transport, endosome to Golgi|activation of retrograde transport, endosome to Golgi|upregulation of retrograde (endosome to Golgi) transport Any process that activates or increases the frequency, rate or extent of retrograde transport, endosome to Golgi. GO:1905282 regulation of epidermal growth factor receptor signaling pathway involved in heart process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905282 regulation of EGF receptor signalling pathway involved in cardiac process|regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|regulation of epidermal growth factor receptor signalling pathway involved in heart process|regulation of EGFR signaling pathway involved in heart process|regulation of ERBB1 signaling pathway involved in cardiac process|regulation of EGF receptor signaling pathway involved in cardiac process|regulation of EGF receptor signalling pathway involved in heart process|regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|regulation of epidermal growth factor receptor signalling pathway involved in cardiac process|regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|regulation of ERBB1 signaling pathway involved in heart process|regulation of EGFR signaling pathway involved in cardiac process|regulation of EGF receptor signaling pathway involved in heart process Any process that modulates the frequency, rate or extent of epidermal growth factor receptor signaling pathway involved in heart process. GO:1905283 negative regulation of epidermal growth factor receptor signaling pathway involved in heart process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905283 inhibition of ERBB1 signaling pathway involved in cardiac process|negative regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|inhibition of epidermal growth factor receptor signaling pathway involved in cardiac process|down-regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|down regulation of EGF receptor signaling pathway involved in heart process|inhibition of EGFR signaling pathway involved in cardiac process|down-regulation of epidermal growth factor receptor signalling pathway involved in cardiac process|downregulation of EGF receptor signalling pathway involved in cardiac process|inhibition of EGF receptor signalling pathway involved in heart process|inhibition of EGF receptor signaling pathway involved in heart process|negative regulation of epidermal growth factor receptor signalling pathway involved in cardiac process|down-regulation of EGF receptor signaling pathway involved in cardiac process|negative regulation of EGF receptor signaling pathway involved in cardiac process|down regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|down-regulation of ERBB1 signaling pathway involved in heart process|negative regulation of ERBB1 signaling pathway involved in heart process|downregulation of epidermal growth factor receptor signaling pathway involved in heart process|down regulation of epidermal growth factor receptor signalling pathway involved in heart process|downregulation of EGFR signaling pathway involved in heart process|down regulation of ERBB1 signaling pathway involved in cardiac process|downregulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|down regulation of epidermal growth factor receptor signaling pathway involved in heart process|downregulation of epidermal growth factor receptor signalling pathway involved in heart process|down regulation of EGFR signaling pathway involved in heart process|inhibition of ERBB1 signaling pathway involved in heart process|downregulation of ERBB1 signaling pathway involved in cardiac process|inhibition of epidermal growth factor receptor signaling pathway involved in heart process|negative regulation of EGF receptor signalling pathway involved in cardiac process|down-regulation of EGF receptor signalling pathway involved in cardiac process|negative regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|down-regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|downregulation of EGF receptor signaling pathway involved in cardiac process|inhibition of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|inhibition of EGFR signaling pathway involved in heart process|down-regulation of EGFR signaling pathway involved in cardiac process|negative regulation of EGFR signaling pathway involved in cardiac process|inhibition of epidermal growth factor receptor signalling pathway involved in cardiac process|down regulation of EGF receptor signalling pathway involved in heart process|down-regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|down regulation of EGF receptor signaling pathway involved in cardiac process|negative regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|down-regulation of epidermal growth factor receptor signalling pathway involved in heart process|downregulation of EGF receptor signalling pathway involved in heart process|negative regulation of epidermal growth factor receptor signalling pathway involved in heart process|down-regulation of ERBB1 signaling pathway involved in cardiac process|negative regulation of EGF receptor signaling pathway involved in heart process|negative regulation of ERBB1 signaling pathway involved in cardiac process|down regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|down-regulation of EGF receptor signaling pathway involved in heart process|downregulation of epidermal growth factor receptor signaling pathway involved in cardiac process|down regulation of epidermal growth factor receptor signalling pathway involved in cardiac process|down regulation of ERBB1 signaling pathway involved in heart process|downregulation of EGFR signaling pathway involved in cardiac process|inhibition of EGF receptor signaling pathway involved in cardiac process|inhibition of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|inhibition of EGF receptor signalling pathway involved in cardiac process|downregulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|inhibition of epidermal growth factor receptor signalling pathway involved in heart process|down regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|downregulation of epidermal growth factor receptor signalling pathway involved in cardiac process|downregulation of ERBB1 signaling pathway involved in heart process|down regulation of EGFR signaling pathway involved in cardiac process|down-regulation of EGF receptor signalling pathway involved in heart process|negative regulation of EGF receptor signalling pathway involved in heart process|downregulation of EGF receptor signaling pathway involved in heart process|down-regulation of epidermal growth factor receptor signaling pathway involved in heart process|negative regulation of EGFR signaling pathway involved in heart process|down-regulation of EGFR signaling pathway involved in heart process|down regulation of EGF receptor signalling pathway involved in cardiac process Any process that stops, prevents or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway involved in heart process. GO:1905284 positive regulation of epidermal growth factor receptor signaling pathway involved in heart process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905284 activation of ERBB1 signaling pathway involved in heart process|positive regulation of ERBB1 signaling pathway involved in heart process|upregulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|activation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|positive regulation of EGFR signaling pathway involved in heart process|activation of EGF receptor signaling pathway involved in cardiac process|activation of epidermal growth factor receptor signalling pathway involved in cardiac process|upregulation of epidermal growth factor receptor signalling pathway involved in heart process|up regulation of epidermal growth factor receptor signaling pathway involved in heart process|up-regulation of EGF receptor signalling pathway involved in heart process|upregulation of ERBB1 signaling pathway involved in cardiac process|upregulation of EGF receptor signaling pathway involved in heart process|up regulation of EGFR signaling pathway involved in heart process|up regulation of EGF receptor signalling pathway involved in cardiac process|up-regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|up-regulation of EGFR signaling pathway involved in cardiac process|positive regulation of EGF receptor signalling pathway involved in cardiac process|up-regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|positive regulation of EGF receptor signaling pathway involved in cardiac process|up-regulation of epidermal growth factor receptor signalling pathway involved in cardiac process|up regulation of EGF receptor signaling pathway involved in cardiac process|activation of epidermal growth factor receptor signaling pathway involved in cardiac process|up regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|up-regulation of ERBB1 signaling pathway involved in heart process|activation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|activation of EGF receptor signalling pathway involved in cardiac process|upregulation of EGF receptor signalling pathway involved in heart process|activation of EGFR signaling pathway involved in cardiac process|up-regulation of EGF receptor signaling pathway involved in heart process|activation of EGF receptor signaling pathway involved in heart process|upregulation of epidermal growth factor receptor signaling pathway involved in heart process|up regulation of ERBB1 signaling pathway involved in cardiac process|positive regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|up regulation of epidermal growth factor receptor signalling pathway involved in heart process|activation of epidermal growth factor receptor signalling pathway involved in heart process|upregulation of EGFR signaling pathway involved in heart process|positive regulation of epidermal growth factor receptor signalling pathway involved in heart process|positive regulation of ERBB1 signaling pathway involved in cardiac process|upregulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|positive regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|positive regulation of EGFR signaling pathway involved in cardiac process|up-regulation of EGF receptor signalling pathway involved in cardiac process|upregulation of epidermal growth factor receptor signalling pathway involved in cardiac process|up regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|upregulation of EGF receptor signaling pathway involved in cardiac process|up regulation of EGFR signaling pathway involved in cardiac process|upregulation of ERBB1 signaling pathway involved in heart process|activation of ERBB1 signaling pathway involved in cardiac process|activation of epidermal growth factor receptor signaling pathway involved in heart process|up-regulation of epidermal growth factor receptor signaling pathway involved in heart process|up regulation of EGF receptor signalling pathway involved in heart process|activation of EGFR signaling pathway involved in heart process|activation of EGF receptor signalling pathway involved in heart process|up-regulation of EGFR signaling pathway involved in heart process|positive regulation of EGF receptor signaling pathway involved in heart process|up-regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|positive regulation of EGF receptor signalling pathway involved in heart process|up-regulation of ERBB1 signaling pathway involved in cardiac process|up regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|up-regulation of epidermal growth factor receptor signalling pathway involved in heart process|up regulation of EGF receptor signaling pathway involved in heart process|upregulation of EGF receptor signalling pathway involved in cardiac process|upregulation of epidermal growth factor receptor signaling pathway involved in cardiac process|up regulation of epidermal growth factor receptor signalling pathway involved in cardiac process|positive regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|up-regulation of EGF receptor signaling pathway involved in cardiac process|upregulation of EGFR signaling pathway involved in cardiac process|up regulation of ERBB1 signaling pathway involved in heart process|positive regulation of epidermal growth factor receptor signalling pathway involved in cardiac process Any process that activates or increases the frequency, rate or extent of epidermal growth factor receptor signaling pathway involved in heart process. GO:1905285 fibrous ring of heart morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905285 coronary tendon morphogenesis|Lower's ring morphogenesis|aortic annulus morphogenesis|atrioventricular ring morphogenesis|anulus fibrosus cordis morphogenesis|anulus fibrosus of heart morphogenesis|annulus fibrosus cordis morphogenesis The developmental process by which a fibrous ring of heart is generated and organized. GO:1905286 serine-type peptidase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1905286 Factor VII - TF complex A protein complex which is capable of serine-type peptidase activity. GO:1905287 positive regulation of G2/M transition of mitotic cell cycle involved in cellular response to nitrogen starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905287 positive regulation of mitotic entry involved in cellular response to nitrogen starvation Any positive regulation of G2/M transition of mitotic cell cycle that is involved in cellular response to nitrogen starvation. GO:1905288 vascular associated smooth muscle cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905288 vascular smooth muscle cell apoptosis|vascular associated smooth muscle cell apoptosis|vascular smooth muscle cell apoptotic process|VSMC apoptosis|VSMC apoptotic process Any apoptotic process in a vascular associated smooth muscle cell. GO:1905289 regulation of CAMKK-AMPK signaling cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905289 regulation of stress-activated AMP-activated protein kinase signaling cascade Any process that modulates the frequency, rate or extent of CAMKK-AMPK signaling cascade. GO:0090679 cell differentiation involved in phenotypic switching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090679 A cell differentiation process that is a part of a reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations. GO:1905279 regulation of retrograde transport, endosome to Golgi biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905279 regulation of retrograde (endosome to Golgi) transport Any process that modulates the frequency, rate or extent of retrograde transport, endosome to Golgi. GO:0090677 reversible differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090677 A phenotypic switching process where a cell reversibly differentiates and dedifferentiates from one cell type into another. GO:0090678 cell dedifferentiation involved in phenotypic switching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090678 A cell dedifferentiation process that is a part of a reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations. GO:0075050 obsolete positive regulation of symbiont cell wall strengthening involved in entry into host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075050 positive regulation of symbiont cell wall strengthening during entry into host OBSOLETE. Any process that activates, maintains or increases the frequency, rate or extent of symbiont cell wall strengthening during entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075051 obsolete negative regulation of symbiont cell wall strengthening involved in entry into host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075051 negative regulation of symbiont cell wall strengthening during entry into host OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont cell wall strengthening during entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0090671 telomerase RNA localization to Cajal body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090671 A process in which telomerase RNA (TERC) is transported to, or maintained in, a Cajal body. GO:0075052 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075052 GO:0090672 telomerase RNA localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090672 Any process in which telomerase RNA is transported to, or maintained in, a specific location. GO:0075053 penetration peg formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075053 symbiont penetration peg formation for entry into host|initiation of symbiont penetration peg|symbiont penetration peg initiation|formation of symbiont penetration peg for entry into host The assembly by the symbiont of a peg-like structure for the purpose of penetration into its host organism, which penetrates through the host cuticle and epidermal cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075054 modulation of penetration peg formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075054 modulation of symbiont penetration peg formation for entry into host|modulation of symbiont penetration peg initiation Any process that modulates the frequency, rate or extent of symbiont penetration peg formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075055 positive regulation of penetration peg formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075055 positive regulation of symbiont penetration peg initiation|positive regulation of symbiont penetration peg formation for entry into host Any process that activates, maintains or increases the frequency, rate or extent of symbiont penetration peg formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0090670 RNA localization to Cajal body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090670 A process in which an RNA is transported to, or maintained in, a Cajal body. GO:0075056 obsolete negative regulation of penetration peg formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075056 negative regulation of symbiont penetration peg initiation|negative regulation of symbiont penetration peg formation for entry into host OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont penetration peg formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0090675 intermicrovillar adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090675 The biological adhesion process by which adjacent microvilli attach to each other through Ca(2+)-dependent adhesion links made of protocadherin-24 and mucin-like protocadherin. GO:0099009 viral genome circularization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099009 VZ:3968 The circularization of a viral genome following infection of a host cell. This is common amongst bacterial viruses to protect the viral genome ends from nucleases, to convert the linear genome to an integrative precursor or to give rise to the replicative form of the genome. It can be mediated by covalent closure of the DNA sticky ends, recombinaison between redundant terminal sequences or via the binding of a protein at the viral DNA extremities. GO:0075057 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075057 GO:0090676 calcium ion transmembrane transport via low voltage-gated calcium channel biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090676 generation of T-type calcium current A process in which a calcium ion is transported from one side of a membrane to the other by means of a low voltage-gated calcium channel. GO:0075058 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075058 GO:0090673 endothelial cell-matrix adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090673 The binding of an endothelial cell to the extracellular matrix via adhesion molecules. GO:0099007 extrinsic component of presynaptic endosome membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099007 The component of the presynaptic endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:0090674 endothelial cell-matrix adhesion via fibronectin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090674 The binding of an endothelial cell to the extracellular matrix via fibronectin. GO:0075059 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075059 GO:0099008 viral entry via permeabilization of inner membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099008 VZ:985 viral penetration via permeabilization of host membrane The entry of a non-enveloped virus into the cytoplasm of a host prokaryotic cell, following fusion with the outer membrane, via permeabilization of the plasma (inner) membrane. In the case of some double stranded RNA viruses of prokaryotes this occurs via interaction of a membrane-interacting component of the capsid, leading to depolarization an permeabilization of the plasma membrane. GO:0099058 integral component of postsynaptic endocytic zone membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099058 The component of the postsynaptic endocytic zone membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0099059 integral component of presynaptic active zone membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099059 The component of the presynaptic active zone membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0099056 integral component of presynaptic membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099056 integral component of presynaptic plasma membrane The component of the presynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0099057 integral component of presynaptic endocytic zone membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099057 The component of the presynaptic endocytic zone membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:1905290 negative regulation of CAMKK-AMPK signaling cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905290 down-regulation of stress-activated AMP-activated protein kinase signaling cascade|negative regulation of stress-activated AMP-activated protein kinase signaling cascade|downregulation of CAMKK-AMPK signaling cascade|down regulation of CAMKK-AMPK signaling cascade|inhibition of CAMKK-AMPK signaling cascade|inhibition of stress-activated AMP-activated protein kinase signaling cascade|down regulation of stress-activated AMP-activated protein kinase signaling cascade|downregulation of stress-activated AMP-activated protein kinase signaling cascade|down-regulation of CAMKK-AMPK signaling cascade Any process that stops, prevents or reduces the frequency, rate or extent of CAMKK-AMPK signaling cascade. GO:0099054 presynapse assembly biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099054 presynaptic terminal assembly|presynapse biogenesis The aggregation, arrangement and bonding together of a set of components to form a presynapse. GO:1905291 positive regulation of CAMKK-AMPK signaling cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905291 up regulation of CAMKK-AMPK signaling cascade|activation of stress-activated AMP-activated protein kinase signaling cascade|up-regulation of stress-activated AMP-activated protein kinase signaling cascade|upregulation of CAMKK-AMPK signaling cascade|upregulation of stress-activated AMP-activated protein kinase signaling cascade|up-regulation of CAMKK-AMPK signaling cascade|activation of CAMKK-AMPK signaling cascade|up regulation of stress-activated AMP-activated protein kinase signaling cascade|positive regulation of stress-activated AMP-activated protein kinase signaling cascade Any process that activates or increases the frequency, rate or extent of CAMKK-AMPK signaling cascade. GO:1905292 regulation of neural crest cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905292 Any process that modulates the frequency, rate or extent of neural crest cell differentiation. GO:0099055 integral component of postsynaptic membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099055 The component of the postsynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0099052 vesicle scission involved in clathrin-mediated endocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099052 The membrane scission process that is the final step in the formation of a clathrin-coated endocytic vesicle: separation from the plasma membrane. GO:1905293 negative regulation of neural crest cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905293 inhibition of neural crest cell differentiation|down regulation of neural crest cell differentiation|downregulation of neural crest cell differentiation|down-regulation of neural crest cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of neural crest cell differentiation. GO:0099053 activating signal cointegrator 1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0099053 ASC-1 complex A protein complex that contains TRIP4 (ASC1) and acts a transcriptional coactivator by interacting with transcription factors such as NF-kappa B. In humans this complex has 4 subunits: TRIP4 + ASCC1-3. GO:1905294 positive regulation of neural crest cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905294 up-regulation of neural crest cell differentiation|upregulation of neural crest cell differentiation|up regulation of neural crest cell differentiation|activation of neural crest cell differentiation Any process that activates or increases the frequency, rate or extent of neural crest cell differentiation. GO:1905295 regulation of neural crest cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905295 Any process that modulates the frequency, rate or extent of neural crest cell fate specification. GO:0099050 vesicle scission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099050 The membrane scission process that is the final step in the formation of a vesicle, leading to separation from its parent membrane. Vesicle scission involves the constriction of a neck-forming protein complex, consisting e.g. of dynamin, around the budded membrane, leading to vesicle closure during its separation from the parent membrane. GO:0099051 vesicle scission involved in endocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099051 The membrane scission process that is the final step in the formation of an endocytic vesicle: separation from the plasma membrane. GO:1905296 negative regulation of neural crest cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905296 down-regulation of neural crest cell fate specification|downregulation of neural crest cell fate specification|down regulation of neural crest cell fate specification|inhibition of neural crest cell fate specification Any process that stops, prevents or reduces the frequency, rate or extent of neural crest cell fate specification. GO:1905297 positive regulation of neural crest cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905297 upregulation of neural crest cell fate specification|up-regulation of neural crest cell fate specification|activation of neural crest cell fate specification|up regulation of neural crest cell fate specification Any process that activates or increases the frequency, rate or extent of neural crest cell fate specification. GO:1905298 regulation of intestinal epithelial cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905298 Any process that modulates the frequency, rate or extent of intestinal epithelial cell development. GO:1905299 negative regulation of intestinal epithelial cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905299 down-regulation of intestinal epithelial cell development|downregulation of intestinal epithelial cell development|down regulation of intestinal epithelial cell development|inhibition of intestinal epithelial cell development Any process that stops, prevents or reduces the frequency, rate or extent of intestinal epithelial cell development. CHEBI:487869 clavulanate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_487869 GO:0075080 obsolete negative regulation by host of symbiont receptor-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075080 OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075081 obsolete modulation by host of symbiont transmembrane receptor-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075081 OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075082 obsolete positive regulation by host of symbiont transmembrane receptor-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075082 OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075083 obsolete negative regulation by host of symbiont transmembrane receptor-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075083 OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075084 obsolete modulation by host of symbiont transmembrane receptor-mediated cAMP signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075084 modulation by host of symbiont transmembrane receptor-mediated cAMP signaling OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of transmembrane receptor-mediated cAMP signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075085 obsolete positive regulation by host of symbiont transmembrane receptor-mediated cAMP signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075085 promotion by host of symbiont transmembrane receptor protein activity involved in cAMP-mediated signal transduction|upregulation by host of symbiont transmembrane receptor-mediated cAMP signal transduction|positive regulation by host of symbiont transmembrane receptor-mediated cAMP signaling|activation by host of symbiont transmembrane receptor-mediated cAMP signal transduction|stimulation by host of symbiont transmembrane receptor-mediated cAMP signal transduction OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of transmembrane receptor-mediated cAMP signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075086 obsolete negative regulation by host of symbiont transmembrane receptor-mediated cAMP signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075086 inhibition by host of symbiont transmembrane receptor-mediated cAMP signal transduction|downregulation by host of symbiont transmembrane receptor-mediated cAMP signal transduction|negative regulation by host of symbiont transmembrane receptor-mediated cAMP signaling OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of transmembrane receptor-mediated cAMP signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075087 obsolete modulation by host of symbiont G protein-coupled receptor signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075087 modulation by host of symbiont G-protein coupled receptor protein signal transduction OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of the symbiont G protein-coupled receptor signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075088 obsolete positive regulation by host of symbiont G protein-coupled receptor signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075088 positive regulation by host of symbiont G-protein coupled receptor protein signal transduction OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of the symbiont G protein-coupled receptor signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075089 obsolete negative regulation by host of symbiont G protein-coupled receptor signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075089 negative regulation by host of symbiont G-protein coupled receptor protein signal transduction OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont G protein-coupled receptor signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:5001 fenofibrate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_5001 GO:0099069 synaptic vesicle tethering involved in synaptic vesicle exocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099069 The initial, indirect interaction between a synaptic vesicle membrane and a the preseynaptic membrane active zone. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. This process is distinct from and prior to synaptic vesicle priming and fusion. GO:0099067 integral component of presynaptic endosome membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099067 The component of the presynaptic endosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0099068 postsynapse assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099068 postsynapse biogenesis The aggregation, arrangement and bonding together of a set of components to form a postsynapse. GO:0099065 integral component of spine apparatus membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099065 The component of the spine apparatus membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0099066 integral component of neuronal dense core vesicle membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099066 The component of the neuronal dense core vesicle membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0099063 integral component of postsynaptic recycling endosome membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099063 The component of the postsynaptic recycling endosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0099064 integral component of postsynaptic endosome membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099064 The component of the postsynaptic endosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0099061 integral component of postsynaptic density membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099061 The component of the postsynaptic density membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0099062 integral component of postsynaptic early endosome membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099062 The component of the postsynaptic early endosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0099060 integral component of postsynaptic specialization membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099060 The component of the postsynaptic specialization membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. CHEBI:5019 ferrichrome biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_5019 CHEBI:5017 ferredoxin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_5017 GO:0075070 adhesion of symbiont hyphopodium to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075070 adhesion of symbiont hyphopodium to host during symbiotic interaction The attachment of a hyphopodium of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075071 modulation by symbiont of host autophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075071 autophagy during symbiotic interaction|autophagy involved in symbiotic interaction|modulation by symbiont of host autophagic process Any process in which a symbiont organism modulates the frequency, rate or extent of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075072 obsolete autophagy of symbiont cells involved in interaction with host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075072 autophagy of symbiont cells during interaction with host OBSOLETE. The process in which symbiont cells digest parts of their own cytoplasm during interaction with its host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075073 obsolete autophagy of symbiont cells on or near host surface biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075073 OBSOLETE. The process in which symbiont cells digest parts of their own cytoplasm, occurring when the symbiont is on or near its host surface. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075074 obsolete spore autophagy involved in appressorium formation on or near host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075074 spore autophagy during appressorium formation on or near host|autophagy of spores during appressorium formation on or near host OBSOLETE. The process in which a symbiont spore digests parts of its own cytoplasm, occurring when the appressorium forms on or near the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075075 modulation by host of symbiont adenylate cyclase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075075 Any process in which the host organism modulates the frequency, rate or extent of the symbiont adenylate cyclase activity, which catalyze the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075076 positive regulation by host of symbiont adenylate cyclase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075076 Any process in which the host organism activates, maintains or increases the frequency, rate or extent of the symbiont adenylate cyclase activity, which catalyze the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075077 negative regulation by host of symbiont adenylate cyclase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075077 Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont adenylate cyclase activity, which catalyze the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075078 obsolete modulation by host of symbiont receptor-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075078 OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of receptor-mediated signal transduction in the symbiont. The receptor is defined as a protein on the cell membrane or within the cytoplasm or cell nucleus that binds to a specific molecule (a ligand) such as a neurotransmitter or a hormone or other substance, and initiates the cellular response to the ligand. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075079 obsolete positive regulation by host of symbiont receptor-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075079 OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0099038 ceramide floppase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0099038 ATP-dependent ceramide transporter activity|ATPase-coupled ceramide transporter activity|ceramide-translocating ATPase activity|ceramide floppase activity (cytosolic to exoplasmic leaftlet) Catalysis of the movement of ceramide from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP. GO:0099039 sphingolipid translocation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099039 The movement of a sphingolipid molecule from one leaflet of a membrane bilayer to the opposite leaflet. GO:0099036 anchored component of neuronal dense core vesicle membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099036 The component of the neuronal dense core vesicle membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. GO:0099037 anchored component of presynaptic endosome membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099037 The component of the presynaptic endosome membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. GO:0002089 lens morphogenesis in camera-type eye biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002089 lens morphogenesis|lens morphogenesis in camera-style eye The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus. GO:0099034 anchored component of postsynaptic endosome membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099034 The component of the postsynaptic endosome membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. GO:0099035 anchored component of spine apparatus membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099035 The component of the spine apparatus membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. GO:0099032 anchored component of postsynaptic early endosome membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099032 The component of the postsynaptic early endosome membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. GO:0099033 anchored component of postsynaptic recycling endosome membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099033 The component of the postsynaptic recycling endosome membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. GO:0002085 inhibition of neuroepithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002085 negative regulation of neural plate formation|repression of premature neural plate formation Any process that prevents the activation of neuroepithelial cell differentiation. Neuroepithelial cell differentiation is the process in which epiblast cells acquire specialized features of neuroepithelial cells. GO:0099030 anchored component of postsynaptic specialization membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099030 The component of the postsynaptic specialization membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. GO:0002086 diaphragm contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002086 A process in which force is generated within involuntary skeletal muscle tissue, resulting in a change in muscle geometry. This process occurs in the diaphragm. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The diaphragm is a striated muscle that is necessary for the process of respiratory gaseous exchange. GO:0099031 anchored component of postsynaptic density membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099031 The component of the postsynaptic density membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. GO:0002087 regulation of respiratory gaseous exchange by nervous system process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002087 regulation of respiratory gaseous exchange by neurological system process|neurological control of breathing A process carried out by the nervous system that is required for the proper control of respiratory gaseous exchange. This process occurs in the respiratory center of the brain in vertebrates. GO:0002088 lens development in camera-type eye biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002088 lens development|lens development in camera-style eye The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus. GO:0002081 outer acrosomal membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0002081 The acrosomal membrane region that underlies the plasma membrane of the sperm. This membrane fuses with the sperm plasma membrane as part of the acrosome reaction. GO:0002082 regulation of oxidative phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002082 OXPHOS Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis. GO:0002083 4-hydroxybenzoate decaprenyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0002083 Reactome:R-HSA-2162192|EC:2.5.1.39|MetaCyc:RXN-9230|RHEA:44564 Catalysis of the reaction: all-trans-decaprenyl diphosphate + 4-hydroxybenzoate = 3-decaprenyl-4-hydroxybenzoate + diphosphate. GO:0002084 protein depalmitoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002084 The removal of palymitoyl groups from a lipoprotein. GO:0002090 regulation of receptor internalization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002090 Any process that modulates the frequency, rate or extent of receptor internalization. GO:0002091 negative regulation of receptor internalization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002091 down-regulation of receptor internalization|downregulation of receptor internalization|down regulation of receptor internalization|inhibition of receptor internalization Any process that stops, prevents, or reduces the frequency, rate or extent of receptor internalization. GO:0099049 clathrin coat assembly involved in endocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099049 The process that results in the assembly of clathrin triskelia into a clathrin cage during endocytosis. Clathrin is recruited to the plasma membrane via interaction with scaffolding proteins that bridge between clathtin and cell surface receptors. Clathrin coat formation is concomittant with coated pit formation leading to endocytic vesicle formation. GO:0099047 clearance of foreign intracellular RNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099047 A defense process that protects an organism from invading foreign RNA. GO:0099048 CRISPR-cas system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099048 An adaptive immune response of bacteria that serves to clear host cells of foreign DNA and RNA. It has three distinct stage: acquisition of foreign DNA by integration into CRISPR loci in the host chromosome, CRISPR RNA (crRNA) biogenesis, and target interference. CISPR stands for Clustered Regularly Interspaced Short Palindromic Repeat, which describes the nature of the loci. GO:0099045 viral extrusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099045 VZ:3951 The process whereby a filamentous phage particle is released from a bacterial host cell via a concerted mechanism of assembly and secretion. Neosynthesized virions are coordinately exported as they are assembled at the cell surface in a secretory process that leaves the host cell fully viable. Non-capsid proteins form structures that facilitate translocation through the inner membrane and outer membranes. A viral single-stranded DNA binding protein coats progeny viral DNA molecules to generate the intracellular precursor for assembly of phage particles as they are extruded through the membranes of the bacterial host. The structural proteins of the virus are anchored in the inner membrane before their incorporation into the phage particle. As assembly proceeds, the phage genome traverses the inner and outer membranes until the entire DNA molecule has been coated and extruded. GO:0099046 clearance of foreign intracellular nucleic acids biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099046 A defense process that protects an organism from DNA or RNA from an invading organism. GO:0099043 cargo loading involved in clathrin-dependent endocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099043 Formation of a macromolecular complex during clathrin-dependent endocytosis that connects the assembling clathrin coat to the proteins and/or lipoproteins to be transported in an endocytic vesicle. This complex includes a receptor and an adaptor protein that links the receptor to the clathrin coat. GO:0099044 vesicle tethering to endoplasmic reticulum biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099044 The initial, indirect interaction between a transport vesicle membrane and the membrane of the endoplasmic reticulum. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior fusion. GO:0002096 polkadots biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0002096 A punctate, filamentous structure composed of Bcl10 that appears in the cytoplasm of T-cells shortly after T-cell receptor stimulation. Polkadots stands for Punctate Oligomeric Killing and Activating DOmains Transducing Signals. GO:0099041 vesicle tethering to Golgi biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099041 The initial, indirect interaction between a transport vesicle membrane and the membrane of the Golgi. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior fusion. GO:0002097 tRNA wobble base modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002097 The process in which the nucleotide at position 34 in the anticodon of a tRNA is post-transcriptionally modified. GO:0099042 nucleation of clathrin-coated pit biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099042 The first step in clathrin-dependent endocytosis: invagination of the plasma membrane to form a pit. GO:0002098 tRNA wobble uridine modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002098 The process in which a uridine in position 34 of a tRNA is post-transcriptionally modified. GO:0099040 ceramide translocation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099040 The movement of a ceramide molecule from one leaflet of a membrane bilayer to the opposite leaflet. GO:0002099 tRNA wobble guanine modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002099 The process in which a guanine in t position 34 of a tRNA is post-transcriptionally modified. GO:0002092 positive regulation of receptor internalization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002092 upregulation of receptor internalization|stimulation of receptor internalization|up-regulation of receptor internalization|activation of receptor internalization|up regulation of receptor internalization Any process that activates or increases the frequency, rate or extent of receptor internalization. GO:0002093 auditory receptor cell morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002093 hair cell morphogenesis Any process that alters the size or shape of an auditory receptor cell. GO:0002094 polyprenyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0002094 Catalysis of the transfer of multiple prenyl groups from one compound (donor) to another (acceptor). GO:0002095 caveolar macromolecular signaling complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0002095 caveolar macromolecular signalling complex A complex composed of proteins required for beta adrenergic receptor activation of protein kinase A. It includes the Cav 12. subunit of L-type calcium channel, protein kinase A regulatory subunit 2(PKAR2), adenyl cyclase, beta-adrenergic receptor, G-alpha-S, protein phosphatase 2A (PP2A) and caveolin 3 (CAV3). GO:0075090 obsolete modulation by host of symbiont signal transduction mediated by G-protein alpha subunit biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075090 OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of the symbiont signal transduction mediated by G-protein alpha subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075091 obsolete positive regulation by host of symbiont signal transduction mediated by G-protein alpha subunit biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075091 OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of the symbiont signal transduction mediated by G-protein alpha subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075092 obsolete negative regulation by host of symbiont signal transduction mediated by G-protein alpha subunit biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075092 OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont signal transduction mediated by G-protein alpha subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075093 obsolete modulation by host of symbiont signal transduction mediated by G-protein beta subunit biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075093 OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of the symbiont signal transduction mediated by G-protein beta subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075094 obsolete positive regulation by host of symbiont signal transduction mediated by G-protein beta subunit biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075094 OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of the symbiont signal transduction mediated by G-protein beta subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075095 obsolete negative regulation by host of symbiont signal transduction mediated by G-protein beta subunit biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075095 OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont signal transduction mediated by G-protein beta subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075096 obsolete modulation by host of symbiont signal transduction mediated by G-protein gamma subunit biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075096 OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of the symbiont signal transduction mediated by G-protein gamma subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075097 obsolete positive regulation by host of symbiont signal transduction mediated by G-protein gamma subunit biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075097 OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of the symbiont signal transduction mediated by G-protein gamma subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075098 obsolete negative regulation by host of symbiont signal transduction mediated by G-protein gamma subunit biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075098 OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont signal transduction mediated by G-protein gamma subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075099 obsolete modulation by host of symbiont protein kinase-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075099 OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of protein kinase-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0090602 sieve element enucleation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090602 The process in which nucleated precursor cells lose their nucleus as part of sieve element differentiation. The nuclear contents are released and degraded in the cytoplasm at the same time as other organelles are rearranged and the cytosol is degraded. GO:0090603 sieve element differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090603 The process whereby a relatively unspecialized cell acquires specialized features of a sieve element. GO:0090600 alpha-1,3-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090600 Catalysis of the hydrolysis of terminal, non-reducing alpha-(1->3)-linked alpha-D-glucose residues with release of alpha-D-glucose. GO:0090601 enucleation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090601 The process in which nucleated precursor cells lose their nucleus. GO:0090606 single-species surface biofilm formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090606 multicellular pellicle formation A process in which microorganisms produce an extracellular matrix and form multicellular aggregates at an air-liquid interface. GO:0090607 multi-species surface biofilm formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090607 A process in which planktonically growing microorganisms of different species grow at the surface of a liquid-air interface and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription. GO:0090604 surface biofilm formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090604 A process in which planktonically growing microorganisms grow at the surface of a liquid-air interface and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription. GO:0090605 submerged biofilm formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090605 solid substrate biofilm formation A process in which planktonically growing microorganisms aggregate and grow on solid substrates under the flow of a liquid and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription. GO:0051005 negative regulation of lipoprotein lipase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051005 inhibition of lipoprotein lipase activity|down regulation of lipoprotein lipase activity|downregulation of lipoprotein lipase activity|down-regulation of lipoprotein lipase activity Any process that stops or reduces the activity of the enzyme lipoprotein lipase. GO:0051006 positive regulation of lipoprotein lipase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051006 up-regulation of lipoprotein lipase activity|upregulation of lipoprotein lipase activity|up regulation of lipoprotein lipase activity|activation of lipoprotein lipase activity|stimulation of lipoprotein lipase activity Any process that activates or increases the activity of the enzyme lipoprotein lipase. GO:0051003 ligase activity, forming nitrogen-metal bonds, forming coordination complexes biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051003 EC:6.6.1.- Catalysis of the ligation of two substances via a nitrogen-metal bond, forming a coordination complex. GO:0051004 regulation of lipoprotein lipase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051004 Any process that modulates the activity of the enzyme lipoprotein lipase. GO:0051009 O-acetylhomoserine sulfhydrylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051009 MetaCyc:ACETYLHOMOSER-CYS-RXN|RHEA:27822 Catalysis of the reaction: O-acetyl-L-homoserine + hydrogen sulfide = homocysteine + acetate. GO:0051007 squalene-hopene cyclase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051007 RHEA:17637|MetaCyc:5.4.99.17-RXN|EC:5.4.99.17 squalene mutase (cyclizing)|squalene:hopene cyclase activity Catalysis of the reaction: squalene = hop-22(29)-ene. GO:0051008 Hsp27 protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051008 Interacting selectively and non-covalently with Hsp27 proteins, a lightweight heat shock protein. GO:0090608 multi-species submerged biofilm formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090608 A process in which planktonically growing microorganisms of different species aggregate and grow on solid substrates under the flow of a liquid and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription. GO:0090609 single-species submerged biofilm formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090609 A process in which planktonically growing microorganisms of the same species aggregate and grow on solid substrates under the flow of a liquid and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription. GO:0090613 5'-deoxyadenosine deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090613 RHEA:42892|EC:3.5.4.41 Catalysis of the reaction: 5'deoxyadenosine + H2O = 5'deoxyinosine + NH3. GO:0090614 5'-methylthioadenosine deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090614 EC:3.5.4.31|RHEA:25025 Catalysis of the reaction: 5'methyl thioadenosine + H2O = 5'methyl thioinosine + NH3. GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090611 The chemical reactions and pathways resulting in the breakdown of a protein or peptide, via the multivesicular body (MVB) sorting pathway; proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation. This process is independent of ubiquitination. GO:0090612 cAMP deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090612 RHEA:22908|EC:3.5.4.46 cyclic adenosine monophosphate deaminase activity Catalysis of the reaction: cyclic adenosine monophosphate + H2O = cyclic inosine monophosphate + NH3. GO:0090617 mitochondrial mRNA 5'-end processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090617 Any process involved in forming the mature 5' end of an mRNA molecule that derives from the mitochondrial genome. GO:0090618 DNA clamp unloading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090618 PCNA unloading The process of removing the PCNA complex from DNA when Okazaki fragments are completed or the replication fork terminates. GO:0090615 mitochondrial mRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090615 Steps involved in processing precursor RNAs arising from transcription of operons in the mitochondrial genome into mature mRNAs. GO:0090616 mitochondrial mRNA 3'-end processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090616 Any process involved in forming the mature 3' end of an mRNA molecule that derives from the mitochondrial genome. GO:0051001 negative regulation of nitric-oxide synthase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051001 down regulation of nitric-oxide synthase activity|inhibition of nitric-oxide synthase activity|NOS inhibitor|nitric-oxide synthase inhibitor|down-regulation of nitric-oxide synthase activity|negative regulation of NOS activity|downregulation of nitric-oxide synthase activity Any process that stops or reduces the activity of the enzyme nitric-oxide synthase. GO:0090610 bundle sheath cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090610 The process in which a cell becomes capable of differentiating autonomously into a bundle sheath cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. GO:0051002 ligase activity, forming nitrogen-metal bonds biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051002 EC:6.6.-.- Catalysis of the joining of a metal ion to a molecule via a nitrogen-metal bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. GO:0051000 positive regulation of nitric-oxide synthase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051000 upregulation of nitric-oxide synthase activity|stimulation of nitric-oxide synthase activity|NOS activator|nitric-oxide synthase activator|activation of nitric-oxide synthase activity|up-regulation of nitric-oxide synthase activity|positive regulation of NOS activity|up regulation of nitric-oxide synthase activity Any process that activates or increases the activity of the enzyme nitric-oxide synthase. GO:0051016 barbed-end actin filament capping biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051016 barbed-end F-actin capping activity|barbed-end actin capping activity|plus-end actin filament capping activity|plus-end F-actin capping activity The binding of a protein or protein complex to the barbed (or plus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits. GO:0051017 actin filament bundle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051017 actin bundling activity|actin cable formation|actin cable assembly The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness. GO:0051014 actin filament severing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051014 F-actin severing|barbed-end actin capping/severing activity|actin filament severing activity The process in which an actin filament is broken down into smaller filaments. GO:0051015 actin filament binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051015 actin cross-linking activity|F-actin binding Interacting selectively and non-covalently with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits. GO:0051018 protein kinase A binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051018 protein kinase A anchoring activity|PKA binding Interacting selectively and non-covalently with any subunit of protein kinase A. GO:0051019 mitogen-activated protein kinase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051019 MAPK binding|MAP kinase binding|MAP-kinase anchoring activity Interacting selectively and non-covalently with a mitogen-activated protein kinase. GO:0051012 microtubule sliding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051012 microtubule translocation The movement of one microtubule along another microtubule. GO:0051013 microtubule severing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051013 microtubule severing activity The process in which a microtubule is broken down into smaller segments. Severing enzymes remove dimers from the middle of the filament to create new ends, unlike depolymerizing kinesins that use ATP to uncap microtubules at their ends. GO:0051010 microtubule plus-end binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051010 Interacting selectively and non-covalently with the plus end of a microtubule. GO:0051011 microtubule minus-end binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051011 Interacting selectively and non-covalently with the minus end of a microtubule. GO:0051027 DNA transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051027 The directed movement of RNA, deoxyribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0051028 mRNA transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051028 The directed movement of mRNA, messenger ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0051025 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051025 GO:0051026 chiasma assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051026 The cell cycle process in which a connection between chromatids assembles, indicating where an exchange of homologous segments has taken place by the crossing-over of non-sister chromatids. GO:0051029 rRNA transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051029 The directed movement of rRNA, ribosomal ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:1905200 gibberellic acid transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905200 The directed movement of gibberellic acid across a membrane. GO:1905201 gibberellin transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1905201 Enables the transfer of gibberellin from one side of a membrane to the other. GO:0051020 GTPase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051020 Interacting selectively and non-covalently with a GTPase, any enzyme that catalyzes the hydrolysis of GTP. GO:0051023 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051023 GO:0051024 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051024 GO:0051021 GDP-dissociation inhibitor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051021 GDI binding Interacting selectively and non-covalently with a GDP-dissociation inhibitor protein. GO:0051022 Rho GDP-dissociation inhibitor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051022 Rho GDI binding Interacting selectively and non-covalently with a Rho GDP-dissociation inhibitor protein. GO:0051038 negative regulation of transcription involved in meiotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051038 downregulation of transcription during meiosis|down regulation of transcription during meiosis|inhibition of transcription during meiosis|down-regulation of transcription during meiosis|negative regulation of transcription, meiotic|negative regulation of meiotic transcription|meiotic repression of transcription Any process that stops, prevents, or reduces the frequency, rate or extent of transcription involved in the meiotic cell cycle. GO:0075005 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075005 GO:0051039 positive regulation of transcription involved in meiotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051039 upregulation of transcription during meiosis|stimulation of transcription during meiosis|up-regulation of transcription during meiosis|activation of transcription during meiosis|positive regulation of meiotic transcription|up regulation of transcription during meiosis|positive regulation of transcription, meiotic Any process that activates or increases the frequency, rate or extent of transcription as part of a meiotic cell cycle. GO:0075006 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075006 GO:0075007 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075007 GO:0051036 regulation of endosome size biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051036 endosome enlargement Any process that modulates the volume of an endosome, a membrane-bounded organelle that carries materials newly ingested by endocytosis. GO:0051037 regulation of transcription involved in meiotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051037 regulation of transcription, meiotic|meiotic regulation of transcription Any process that modulates the frequency, rate or extent of transcription as part of a meiotic cell cycle. GO:0075008 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075008 GO:0075009 germ tube formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075009 germ tube formation on or near host Development of slender tubular outgrowth first produced by most symbiont spores immediately following germination on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:1905210 regulation of fibroblast chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905210 Any process that modulates the frequency, rate or extent of fibroblast chemotaxis. GO:1905211 negative regulation of fibroblast chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905211 down-regulation of fibroblast chemotaxis|inhibition of fibroblast chemotaxis|down regulation of fibroblast chemotaxis|downregulation of fibroblast chemotaxis Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast chemotaxis. GO:1905212 positive regulation of fibroblast chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905212 activation of fibroblast chemotaxis|up-regulation of fibroblast chemotaxis|upregulation of fibroblast chemotaxis|up regulation of fibroblast chemotaxis Any process that activates or increases the frequency, rate or extent of fibroblast chemotaxis. GO:1905202 methylcrotonoyl-CoA carboxylase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1905202 A protein complex which is capable of methylcrotonoyl-CoA carboxylase activity. GO:0090646 mitochondrial tRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090646 The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group, in the mitochondrion. GO:0090647 modulation of age-related behavioral decline biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090647 Any process that modulates the processes that arise as an organism progresses toward the end of its lifespan that results in a decline in behavioral activities such as locomotory behavior, and learning or memory. GO:1905203 regulation of connective tissue replacement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905203 Any process that modulates the frequency, rate or extent of connective tissue replacement. GO:0090644 age-related resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090644 developmental resistance|ARR|mature seedling resistance|ontogenic resistance|senescence-induced resistance|flowering-induced resistance|adult seedling resistance An innate immune response that is positively correlated with host plant development. As a plant develops, its innate resistance to pathogenic infections increases. The mechanisms involved in age-related resistance differ in nature or in aspects of regulation from the hypersensitive response (HR), systemic acquired resistance (SAR), or induced systemic resistance (ISR). GO:1905204 negative regulation of connective tissue replacement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905204 down-regulation of connective tissue replacement|inhibition of connective tissue replacement|down regulation of connective tissue replacement|downregulation of connective tissue replacement Any process that stops, prevents or reduces the frequency, rate or extent of connective tissue replacement. GO:1905205 positive regulation of connective tissue replacement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905205 up regulation of connective tissue replacement|activation of connective tissue replacement|up-regulation of connective tissue replacement|upregulation of connective tissue replacement Any process that activates or increases the frequency, rate or extent of connective tissue replacement. GO:0090645 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090645 GO:1905206 positive regulation of hydrogen peroxide-induced cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905206 upregulation of cell death in response to H2O2|upregulation of hydrogen peroxide-mediated cell death|up-regulation of cell death in response to H2O2|activation of cell death in response to H2O2|up-regulation of cell death in response to hydrogen peroxide|positive regulation of cell death in response to hydrogen peroxide|up regulation of hydrogen peroxide-mediated cell death|upregulation of cell death in response to hydrogen peroxide|positive regulation of hydrogen peroxide-mediated cell death|positive regulation of cell death in response to H2O2|up regulation of cell death in response to H2O2|activation of hydrogen peroxide-mediated cell death|up regulation of cell death in response to hydrogen peroxide|up-regulation of hydrogen peroxide-mediated cell death|activation of cell death in response to hydrogen peroxide Any process that activates or increases the frequency, rate or extent of cell death in response to hydrogen peroxide. GO:1905207 regulation of cardiocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905207 regulation of cardiac cell differentiation|regulation of heart cell differentiation Any process that modulates the frequency, rate or extent of cardiocyte differentiation. GO:1905208 negative regulation of cardiocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905208 down regulation of cardiocyte differentiation|down regulation of heart cell differentiation|inhibition of cardiocyte differentiation|inhibition of heart cell differentiation|negative regulation of cardiac cell differentiation|down-regulation of cardiac cell differentiation|downregulation of cardiac cell differentiation|down-regulation of cardiocyte differentiation|down-regulation of heart cell differentiation|negative regulation of heart cell differentiation|down regulation of cardiac cell differentiation|inhibition of cardiac cell differentiation|downregulation of cardiocyte differentiation|downregulation of heart cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of cardiocyte differentiation. GO:0090648 response to environmental enrichment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090648 response to the introduction of novel objects Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the provision of a combination of complex inanimate and social stimulations in the organism's housing environment. GO:0090649 response to oxygen-glucose deprivation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090649 response to OGD Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the deprivation of oxygen and glucose. GO:1905209 positive regulation of cardiocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905209 up-regulation of cardiac cell differentiation|upregulation of cardiocyte differentiation|activation of cardiac cell differentiation|upregulation of heart cell differentiation|up-regulation of cardiocyte differentiation|activation of cardiocyte differentiation|up-regulation of heart cell differentiation|positive regulation of cardiac cell differentiation|activation of heart cell differentiation|up regulation of cardiac cell differentiation|positive regulation of heart cell differentiation|up regulation of cardiocyte differentiation|upregulation of cardiac cell differentiation|up regulation of heart cell differentiation Any process that activates or increases the frequency, rate or extent of cardiocyte differentiation. GO:0051030 snRNA transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051030 The directed movement of snRNA, small nuclear ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0051031 tRNA transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051031 The directed movement of tRNA, transfer ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0075000 response to host osmotic environment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075000 response of symbiont to host osmotic environment Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the osmotic conditions in or around its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0090642 microsporidian-type exospore biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090642 The dense, protein rich outermost layer of a microsporidian spore wall that lies above the endospore. GO:0075001 adhesion of symbiont infection structure to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075001 adhesion of symbiont infection structure to host during symbiotic interaction|attachment of symbiont infection structure to host The attachment of an infection structure of the symbiont to its host via adhesion molecules, general stickiness etc., either directly or indirectly. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051034 tRNA transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051034 Enables the transfer of tRNA, transfer ribonucleic acid, from one side of a membrane to the other. GO:0090643 inflorescence phyllotactic patterning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090643 The radial pattern formation process that results in the formation of flowers around a central axis in an inflorescence meristem. GO:0075002 adhesion of symbiont germination tube to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075002 adhesion of symbiont germination tube to host during symbiotic interaction The attachment of a germination tube of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051035 DNA transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051035 Enables the transfer of DNA, deoxyribonucleic acid, from one side of a membrane to the other. GO:0075003 adhesion of symbiont appressorium to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075003 adhesion of symbiont appressorium to host during symbiotic interaction The attachment of an appressorium of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0090640 phosphatidylcholine biosynthesis from sn-glycero-3-phosphocholine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090640 The phosphatidylcholine biosynthetic process that involves the two-step acylation of sn-glycero-3-phosphocholine to a phosphatidylcholine. GO:0051032 nucleic acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051032 Enables the transfer of nucleic acids from one side of a membrane to the other. Nucleic acids are single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information. GO:0090641 microsporidian-type endospore biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090641 The middle layer in a microsporidian spore wall that lies under the exospore and outside the plasma membrane, containing chitin and proteins. GO:0051033 RNA transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051033 Reactome:R-HSA-203906 Enables the transfer of RNA, ribonucleic acid, from one side of a membrane to the other. GO:0075004 adhesion of symbiont spore to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075004 adhesion of symbiont spore to host during symbiotic interaction The attachment of a spore of the symbiont to its host via adhesion molecules, general stickiness etc. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051049 regulation of transport biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0051049 Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0051047 positive regulation of secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051047 upregulation of secretion|up regulation of secretion|activation of secretion|stimulation of secretion|up-regulation of secretion Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue. GO:0051048 negative regulation of secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051048 down regulation of secretion|downregulation of secretion|down-regulation of secretion|inhibition of secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue. GO:1905220 negative regulation of platelet formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905220 downregulation of platelet formation|down regulation of platelet formation|inhibition of platelet formation|negative regulation of platelet extrusion|down-regulation of platelet extrusion|down-regulation of platelet formation|downregulation of platelet extrusion|down regulation of platelet extrusion|inhibition of platelet extrusion Any process that stops, prevents or reduces the frequency, rate or extent of platelet formation. GO:1905221 positive regulation of platelet formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905221 upregulation of platelet extrusion|upregulation of platelet formation|activation of platelet extrusion|up-regulation of platelet extrusion|activation of platelet formation|up-regulation of platelet formation|positive regulation of platelet extrusion|up regulation of platelet extrusion|up regulation of platelet formation Any process that activates or increases the frequency, rate or extent of platelet formation. GO:1905222 atrioventricular canal morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905222 ependymal canal morphogenesis|canalis atrioventricularis morphogenesis|atrio-ventricular canal morphogenesis|atrial canal morphogenesis|AV canal morphogenesis|AVC morphogenesis The developmental process by which an atrioventricular canal is generated and organized. GO:1905223 epicardium morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905223 visceral serous pericardium of heart morphogenesis|pericardium visceral mesothelium morphogenesis|visceral serous pericardium proper morphogenesis|heart epicardium morphogenesis The developmental process by which an epicardium is generated and organized. GO:1905213 negative regulation of mitotic chromosome condensation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905213 Any process that stops, prevents or reduces the frequency, rate or extent of mitotic chromosome condensation. GO:0090657 telomeric loop disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090657 t-loop disassembly|T loop disassembly The telomere maintenance process in which telomeric loops are disassembled to permit efficient telomere replication. GO:1905214 regulation of RNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905214 Any process that modulates the frequency, rate or extent of RNA binding. GO:0090658 cone matrix sheath biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090658 A biochemically and structurally distinct domain of the retinal interphotoreceptor matrix that is specifically associated with cone photoreceptor cell inner and outer segments. GO:1905215 negative regulation of RNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905215 down regulation of RNA binding|downregulation of RNA binding|down-regulation of RNA binding|inhibition of RNA binding Any process that stops, prevents or reduces the frequency, rate or extent of RNA binding. GO:0090655 double-stranded/single-stranded junction telomeric DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090655 Interacting selectively and non-covalently with the junction formed at the point where double-stranded telomeric DNA becomes a single-stranded G-rich telomeric DNA 3' overhang. GO:1905216 positive regulation of RNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905216 upregulation of RNA binding|up regulation of RNA binding|activation of RNA binding|up-regulation of RNA binding Any process that activates or increases the frequency, rate or extent of RNA binding. GO:0090656 t-circle formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090656 telomeric circle formation A telomere maintenance process that results in the formation of a telomeric circle, or t-circle. A t-circle is an extrachromosomal duplex or single-stranded circular DNA molecule composed of t-arrays. T-circles are involved in the control of telomere length via alternative-lengthening of telomeres (ALT) pathway and telomere rapid deletion (TRD). GO:1905217 response to astaxanthin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905217 response to (3S,3'S)-3,3'-dihydroxy-beta,beta-carotene-4,4'-dione Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an astaxanthin stimulus. GO:1905218 cellular response to astaxanthin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905218 cellular response to (3S,3'S)-3,3'-dihydroxy-beta,beta-carotene-4,4'-dione Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an astaxanthin stimulus. GO:0090659 walking behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090659 locomotor gait pattern The behavior of an organism relating to the progression of that organism along the ground by the process of lifting and setting down each leg. GO:1905219 regulation of platelet formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905219 regulation of platelet extrusion Any process that modulates the frequency, rate or extent of platelet formation. GO:0051041 positive regulation of calcium-independent cell-cell adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051041 up regulation of calcium-independent cell-cell adhesion|upregulation of calcium-independent cell-cell adhesion|stimulation of calcium-independent cell-cell adhesion|up-regulation of calcium-independent cell-cell adhesion|activation of calcium-independent cell-cell adhesion Any process that activates or increases the frequency, rate or extent of calcium-independent cell-cell adhesion. GO:0051042 negative regulation of calcium-independent cell-cell adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051042 downregulation of calcium-independent cell-cell adhesion|down regulation of calcium-independent cell-cell adhesion|inhibition of calcium-independent cell-cell adhesion|down-regulation of calcium-independent cell-cell adhesion Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-independent cell-cell adhesion. GO:0090650 cellular response to oxygen-glucose deprivation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090650 cellular response to OGD Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the deprivation of oxygen and glucose. GO:0051040 regulation of calcium-independent cell-cell adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051040 Any process that modulates the frequency, rate or extent of the attachment of one cell to another cell via adhesion molecules that do not require the presence of calcium for the interaction. GO:0051045 negative regulation of membrane protein ectodomain proteolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051045 down-regulation of membrane protein ectodomain proteolysis|inhibition of membrane protein ectodomain proteolysis|down regulation of membrane protein ectodomain proteolysis|downregulation of membrane protein ectodomain proteolysis Any process that stops, prevents, or reduces the frequency, rate or extent of membrane protein ectodomain proteolysis. GO:0090653 apical recycling endosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090653 Tubulo-vesicular structure located in the apical cytoplasm that participates in apical cargo recycling in polarized epithelial cells. GO:0051046 regulation of secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051046 Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue. GO:0090654 basolateral recycling endosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090654 Tubulo-vesicular structure located in the basolateral cytoplasm that participates in basolateral cargo recycling in polarized epithelial cells. GO:0090651 apical cytoplasm biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090651 The region of the cytoplasm located at the apical side of the cell. Used in reference to animal polarized epithelial cells. GO:0051043 regulation of membrane protein ectodomain proteolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051043 Any process that modulates the frequency, rate or extent of the proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain). GO:0051044 positive regulation of membrane protein ectodomain proteolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051044 activation of membrane protein ectodomain proteolysis|stimulation of membrane protein ectodomain proteolysis|up-regulation of membrane protein ectodomain proteolysis|upregulation of membrane protein ectodomain proteolysis|up regulation of membrane protein ectodomain proteolysis Any process that activates or increases the frequency, rate or extent of membrane protein ectodomain peptidolysis. GO:0090652 basolateral cytoplasm biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090652 The region of the cytoplasm located at the basolateral side of the cell. Used in reference to animal polarized epithelial cells. GO:0075027 positive regulation of appressorium initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075027 positive regulation of appressorium initiation on or near host|positive regulation of initiation of appressorium on or near host Any process that activates or increases the frequency, rate or extent of symbiont appressorium initiation. GO:0075028 negative regulation of appressorium initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075028 negative regulation of appressorium initiation on or near host|negative regulation of initiation of appressorium on or near host Any process that stops, prevents, or reduces the frequency, rate or extent symbiont appressorium initiation. GO:0051058 negative regulation of small GTPase mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051058 inhibition of small GTPase mediated signal transduction|negative regulation of small GTPase-mediated signal transduction|down regulation of small GTPase mediated signal transduction|downregulation of small GTPase mediated signal transduction|down-regulation of small GTPase mediated signal transduction Any process that stops, prevents, or reduces the frequency, rate or extent of small GTPase mediated signal transduction. GO:0075029 formation of appressorium germ tube hook structure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075029 formation of symbiont germ tube hook structure on or near host|symbiont germ tube hook structure formation on or near host|formation of germ tube tip of symbiont on or near the exterior of host|formation of symbiont germ tube hook structure for appressorium development The development of a swollen tip at the growing end of a symbiont spore which usually flattens against the host cell surface prior to appressorium formation. GO:0051059 NF-kappaB binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051059 Interacting selectively and non-covalently with NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters. CHEBI:5070 flavanone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_5070 GO:0090619 meiotic spindle pole biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090619 Either of the ends of a meiotic spindle, a spindle that forms as part of meiosis, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules. GO:1905230 response to borneol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905230 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a borneol stimulus. GO:1905231 cellular response to borneol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905231 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a borneol stimulus. GO:1905232 cellular response to L-glutamate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905232 cellular response to L-glutamate(1-) Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamate(1-) stimulus. GO:1905233 response to codeine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905233 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a codeine stimulus. GO:1905234 cellular response to codeine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905234 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a codeine stimulus. GO:1905224 clathrin-coated pit assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905224 coated pit assembly|clathrin-coated pit formation|coated pit formation The aggregation, arrangement and bonding together of a set of components to form a clathrin-coated pit. GO:0090624 endoribonuclease activity, cleaving miRNA-paired mRNA biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090624 Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an miRNA. GO:1905225 response to thyrotropin-releasing hormone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905225 response to protirelin|response to TRH Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyrotropin-releasing hormone (TRH) stimulus. TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary. GO:0090625 mRNA cleavage involved in gene silencing by siRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090625 The process in which small interfering RNAs (siRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), a siRNA will typically direct cleavage by base pairing with perfect or near-perfect complementarity to the target mRNA. GO:1905226 regulation of adhesion of symbiont to host epithelial cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905226 Any process that modulates the frequency, rate or extent of adhesion of symbiont to host epithelial cell. GO:0090622 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090622 GO:1905227 negative regulation of adhesion of symbiont to host epithelial cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905227 downregulation of adhesion of symbiont to host epithelial cell|down regulation of adhesion of symbiont to host epithelial cell|inhibition of adhesion of symbiont to host epithelial cell|down-regulation of adhesion of symbiont to host epithelial cell Any process that stops, prevents or reduces the frequency, rate or extent of adhesion of symbiont to host epithelial cell. GO:0090623 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090623 GO:1905228 positive regulation of adhesion of symbiont to host epithelial cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905228 upregulation of adhesion of symbiont to host epithelial cell|up-regulation of adhesion of symbiont to host epithelial cell|activation of adhesion of symbiont to host epithelial cell|up regulation of adhesion of symbiont to host epithelial cell Any process that activates or increases the frequency, rate or extent of adhesion of symbiont to host epithelial cell. GO:0090628 plant epidermal cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090628 The process in which a cell becomes capable of differentiating autonomously into a plant epidermal cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. GO:1905229 cellular response to thyrotropin-releasing hormone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905229 cellular response to protirelin|cellular response to TRH Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyrotropin-releasing hormone (TRH) stimulus. TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary. GO:0090629 lagging strand initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090629 The process in which the synthesis of DNA from a template strand in a net 3' to 5' direction is started. GO:0090626 plant epidermis morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090626 The process in which the anatomical structures of the plant epidermis are generated and organized. GO:0090627 plant epidermal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090627 The process in which a relatively unspecialized cell acquires specialized features of a plant epidermal cell. GO:0051052 regulation of DNA metabolic process biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0051052 regulation of DNA metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA. GO:0075020 obsolete calcium or calmodulin-mediated activation of appressorium formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075020 Ca++ or calmodulin-mediated activation of appressorium formation|Ca2+ or calmodulin-mediated activation of appressorium formation OBSOLETE. Any process that modulates the frequency, rate or extent of symbiont calcium or calmodulin-mediated signal transduction during appressorium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051053 negative regulation of DNA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051053 inhibition of DNA metabolic process|negative regulation of DNA metabolism|down regulation of DNA metabolic process|downregulation of DNA metabolic process|down-regulation of DNA metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA. GO:0075021 obsolete cAMP-mediated activation of appressorium formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075021 cyclic AMP mediated activation of appressorium formation OBSOLETE. Any process that modulates the frequency, rate or extent of symbiont cAMP mediated signal transduction during appressorium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051050 positive regulation of transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051050 up regulation of transport|activation of transport|stimulation of transport|up-regulation of transport|upregulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0051051 negative regulation of transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051051 down regulation of transport|downregulation of transport|down-regulation of transport|inhibition of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0075022 obsolete ethylene-mediated activation of appressorium formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075022 OBSOLETE. Any process that modulates the frequency, rate or extent of symbiont ethylene-mediated signal transduction during appressorium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0090620 obsolete APC-Cdc20 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090620 APC-fizzy complex|APC-Slp1 complex|mitotic anaphase promotic complex OBSOLETE. An anaphase promoting complex bound to the fizzy family APC activator Cdc20/Slp1 which regulates the metaphase anaphase transition by activating the APC/C to target the anaphase inhibitor securin and promotes sister chromatid separation. GO:0051056 regulation of small GTPase mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051056 regulation of small GTPase-mediated signal transduction Any process that modulates the frequency, rate or extent of small GTPase mediated signal transduction. GO:0075023 obsolete MAPK-mediated regulation of appressorium formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075023 mitogen-activated protein kinase-mediated activation of appressorium formation OBSOLETE. Any process that modulates the frequency, rate or extent of symbiont MAP kinase-mediated signal transduction during appressorium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0090621 obsolete APC-fizzy-related complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090621 APC-Hct1/Cdh1 complex|APC-Srw1 complex OBSOLETE. An anaphase promoting complex bound to the fizzy-related family APC activator FZR1/Cdh1/Srw1 that regulates mitotic exit by activating the APC/C to target mitotic cyclins for destruction during anaphase and telophase. Is also active during G1. GO:0051057 positive regulation of small GTPase mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051057 up-regulation of small GTPase mediated signal transduction|positive regulation of small GTPase-mediated signal transduction|upregulation of small GTPase mediated signal transduction|up regulation of small GTPase mediated signal transduction|activation of small GTPase mediated signal transduction|stimulation of small GTPase mediated signal transduction Any process that activates or increases the frequency, rate or extent of small GTPase mediated signal transduction. GO:0075024 obsolete phospholipase C-mediated activation of appressorium formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075024 OBSOLETE. Any process that modulates the frequency, rate or extent of symbiont phospholipase C-mediated signal transduction during appressorium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051054 positive regulation of DNA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051054 up-regulation of DNA metabolic process|upregulation of DNA metabolic process|positive regulation of DNA metabolism|up regulation of DNA metabolic process|activation of DNA metabolic process|stimulation of DNA metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA. GO:0075025 initiation of appressorium formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075025 initiation of appressorium by symbiont on or near host|initiation of symbiont appressorium on or near host|appressorium initiation on or near host|initiation of appressorium on or near host The process in which a relatively unspecialized cell starts to acquire specialized features of the symbiont appressorium to aid in infection of the host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051055 negative regulation of lipid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051055 downregulation of lipid biosynthetic process|down regulation of lipid biosynthetic process|inhibition of lipid biosynthetic process|negative regulation of lipid anabolism|negative regulation of lipogenesis|negative regulation of lipid synthesis|negative regulation of lipid formation|down-regulation of lipid biosynthetic process|negative regulation of lipid biosynthesis Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids. GO:0075026 regulation of appressorium initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075026 regulation of initiation of appressorium on or near host|regulation of appressorium initiation on or near host Any process that modulates the frequency, rate or extent of symbiont appressorium initiation. GO:0075016 appressorium formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075016 appressorium formation on or near host|formation of an appressorium by symbiont on or near host|appressorium formation for entry into host, on or near host The process in which a swollen, flattened portion of a symbiont filament is formed on or near its host organism, to adhere to and for the purpose of penetrating the host surface. GO:0075017 regulation of appressorium formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075017 regulation of appressorium formation on or near host Any process that modulates the frequency, rate or extent of symbiont appressorium formation. GO:0051069 galactomannan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051069 galactomannan metabolism The chemical reactions and pathways involving galactomannan, a polysaccharide composed of D-galactose and D-mannose. The mannose units form the backbone structure (a linear main chain) with the D-galactose as single side units. GO:0075018 positive regulation of appressorium formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075018 positive regulation of appressorium formation on or near host Any process that activates or increases the frequency, rate or extent of symbiont appressorium formation. GO:0075019 negative regulation of appressorium formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075019 negative regulation of appressorium formation on or near host Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont appressorium formation. GO:1905240 negative regulation of canonical Wnt signaling pathway involved in osteoblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905240 down-regulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|negative regulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|down regulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|downregulation of canonical Wnt signaling pathway involved in osteoblast differentiation|downregulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|downregulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|down regulation of canonical Wnt signaling pathway involved in osteoblast differentiation|inhibition of canonical Wnt signaling pathway involved in osteoblast differentiation|down regulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|downregulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|inhibition of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|down regulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|negative regulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|down-regulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|inhibition of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|inhibition of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|down-regulation of canonical Wnt signaling pathway involved in osteoblast differentiation|down-regulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|negative regulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation Any process that stops, prevents or reduces the frequency, rate or extent of canonical Wnt signaling pathway involved in osteoblast differentiation. GO:1905241 positive regulation of canonical Wnt signaling pathway involved in osteoblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905241 upregulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|up regulation of canonical Wnt signaling pathway involved in osteoblast differentiation|positive regulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|up regulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|positive regulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|up regulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|up regulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|upregulation of canonical Wnt signaling pathway involved in osteoblast differentiation|activation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|positive regulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|upregulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|upregulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|up-regulation of canonical Wnt signaling pathway involved in osteoblast differentiation|activation of canonical Wnt signaling pathway involved in osteoblast differentiation|up-regulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|up-regulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|activation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|up-regulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|activation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation Any process that activates or increases the frequency, rate or extent of canonical Wnt signaling pathway involved in osteoblast differentiation. GO:1905242 response to 3,3',5-triiodo-L-thyronine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905242 response to Liothyroninum|response to Liothyronine|response to Liothyronin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',5-triiodo-L-thyronine stimulus. GO:1905243 cellular response to 3,3',5-triiodo-L-thyronine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905243 cellular response to Liothyronin|cellular response to Liothyroninum|cellular response to Liothyronine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',5-triiodo-L-thyronine stimulus. GO:1905244 regulation of modification of synaptic structure biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_1905244 regulation of synapse remodelling Any process that modulates the frequency, rate or extent of modification of synaptic structure. GO:1905245 regulation of aspartic-type peptidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905245 Any process that modulates the frequency, rate or extent of aspartic-type peptidase activity. GO:1905235 response to quercetin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905235 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a quercetin stimulus. GO:0090635 extracellular core region of desmosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090635 desmoglea The desmosomal part containing the desmosomal cadherins, desmogleins and desmocollins, that establish contact and adhere to neighboring cells in a Ca2+-dependent manner. GO:0090636 outer dense plaque of desmosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090636 The desmosomal part containing plakoglobins, plakophilins, the N-termini of desmoplakins, as well as the cytoplasmic tails of the desmosomal cadherins, which together attach the plaque to the plasma membrane. GO:1905236 cellular response to quercetin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905236 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a quercetin stimulus. GO:1905237 response to cyclosporin A biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905237 response to cyclophilin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclosporin A stimulus. GO:0090633 keto-deoxynonulosonic acid (KDN) cytidylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090633 CMP-KDN synthetase activity|cytidine 5'-monophospho-2-Keto-3-deoxy-D-glycero-D-galacto-nononic acid synthetase activity Catalysis of the reaction: CTP + KDN = diphosphate + CMP-KDN. GO:1905238 cellular response to cyclosporin A biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905238 cellular response to cyclophilin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclosporin A stimulus. GO:0090634 microglial cell mediated cytotoxicity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090634 The directed killing of a target cell by a microglial cell. GO:1905239 regulation of canonical Wnt signaling pathway involved in osteoblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905239 regulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|regulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|regulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation Any process that modulates the frequency, rate or extent of canonical Wnt signaling pathway involved in osteoblast differentiation. GO:0090639 phosphatidylcholine biosynthesis from choline and CDP-diacylglycerol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090639 The phosphatidylcholine biosynthetic process that involves a one-step direct condensation of choline with CDP-diacylglycerol to form phosphatidylcholine. GO:0051060 pullulanase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051060 MetaCyc:RXN-1824|EC:3.2.1.41 R-enzyme|pullulan 6-glucanohydrolase activity|limit dextrinase|alpha-dextrin endo-1,6-alpha-glucosidase activity|pullulan alpha-1,6-glucanohydrolase activity|amylopectin 6-glucanohydrolase activity|bacterial debranching enzyme|debranching enzyme activity Catalysis of the hydrolysis of (1,6)-alpha-D-glucosidic linkages in pullulan (a linear polymer of alpha-(1,6)-linked maltotriose units) and in amylopectin and glycogen, and the a- and b-limit dextrins of amylopectin and glycogen. GO:0090637 inner dense plaque of desmosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090637 The desmosomal part containing the C-termini of desmoplakins which interact with the keratin intermediate filaments, serving to tether the intermediate filaments to the plasma membrane. GO:0090638 phosphatidylcholine biosynthesis from phosphatidylethanolamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090638 The phosphatidylcholine biosynthetic process that depends on direct conversion of the phosphatidyl-base phosphatidylethanolamine to phosphatidylcholine by successive methylations. GO:0051063 CDP reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051063 MetaCyc:CDPREDUCT-RXN CDP reduction Catalysis of the reaction: dCDP + thioredoxin disulfide + H2O = CDP + thioredoxin. GO:0051064 TTP reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051064 EC:1.17.4.- TTP reduction Catalysis of the reaction: dTTP + thioredoxin disulfide + H2O = TTP + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin. GO:0051061 ADP reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051061 RHEA:28034|MetaCyc:ADPREDUCT-RXN ADP reduction Catalysis of the reaction: dADP + thioredoxin disulfide + H2O = ADP + thioredoxin. GO:0075010 regulation of germ tube formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075010 Any process that modulates the frequency, rate or extent of germ tube formation on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051062 UDP reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051062 RHEA:28026|MetaCyc:UDPREDUCT-RXN UDP reduction Catalysis of the reaction: dUDP + thioredoxin disulfide + H2O = UDP + thioredoxin. GO:0075011 positive regulation of germ tube formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075011 positive regulation of germ tube formation on or near host Any process that activates, maintains or increases the frequency, rate or extent of germ tube formation on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051067 dihydropteridine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051067 6,7-dihydropteridine metabolic process|dihydropteridine reduction|dihydropteridine metabolism The chemical reactions and pathways involving 6,7-dihydropteridine, a bicyclic compound with the formula C6H6N4. GO:0075012 negative regulation of germ tube formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075012 negative regulation of germ tube formation on or near host Any process that stops, prevents, or reduces the frequency, rate or extent of germ tube formation on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0090631 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090631 GO:0090632 N-glycolylneuraminic acid (Neu5Gc) cytidylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090632 CMP-Neu5Gc synthetase activity Catalysis of the reaction: CTP + Neu5Gc = diphosphate + CMP-Neu5Gc. GO:0051068 dihydrolipoamide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051068 dihydrothioctamide metabolism|dihydrolipoamide metabolism|dihydrolipoamide reduction|dihydrothioctamide metabolic process The chemical reactions and pathways involving dihydrolipoamide, the reduced form of lipoamide, produced as an intermediate in the reactions in which lipoamide acts as a cofactor. GO:0075013 obsolete growth or development of symbiont on or near host phyllosphere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075013 growth or development of symbiont on or near host phyllosphere OBSOLETE. The increase in size or mass of symbiont, or the progression of the symbiont from an initial condition to a later condition, occurring on or near its host phyllosphere. The host phyllosphere is defined as total above-ground surfaces of a plant as a habitat for symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:5078 flavonol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_5078 GO:0051065 CTP reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051065 EC:1.17.4.- CTP reduction Catalysis of the reaction: dCTP + thioredoxin disulfide + H2O = CTP + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin. GO:0075014 obsolete growth or development of symbiont on or near host rhizosphere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075014 growth or development of symbiont on or near host rhizosphere OBSOLETE. The increase in size or mass of symbiont, or the progression of the symbiont from an initial condition to a later condition, occurring on or near its host rhizosphere. The host rhizosphere is defined as total below-ground surfaces of a plant as a habitat for its symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0090630 activation of GTPase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090630 Ras GTPase activation|Rap GTPase activation|Cdc42 GTPase activation|Ran GTPase activation|activation of Ras GTPase activity|Ral GTPase activation|activation of Rap GTPase activity|activation of Cdc42 GTPase activity|Rho GTPase activation|activation of Ran GTPase activity|activation of Ral GTPase activity|ARF GTPase activation|Rac GTPase activation|activation of Rho GTPase activity|Rab GTPase activation|activation of ARF GTPase activity|activation of Rac GTPase activity|activation of Rab GTPase activity Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP. GO:0051066 dihydrobiopterin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051066 dihydropterin metabolism|7,8-dihydrobiopterin metabolic process|6,7-dihydrobiopterin metabolic process|dihydropterin metabolic process|dihydrobiopterin reduction The chemical reactions and pathways involving a dihydrobiopterin, a reduced pteridine derivative related to folic acid; it acts as an electron carrier in tyrosine biosynthesis and its quinoid form is produced by oxidation of tetrahydrobiopterin in several biological hydroxylation reactions. GO:0075015 formation of infection structure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075015 formation by symbiont of infection structure on or near host|formation of host penetration structure|formation of infection structure on or near host|formation of host infection structure The formation of a symbiont structure that serves to infect its host organism. It includes physiological, developmental, and morphological changes of the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:55549 dalpatein biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55549 CHEBI:79516 Nonylphenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79516 GO:2000225 negative regulation of testosterone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000225 Any process that stops, prevents, or reduces the frequency, rate or extent of testosterone biosynthetic process. GO:2000226 regulation of pancreatic A cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000226 regulation of pancreatic alpha cell differentiation Any process that modulates the frequency, rate or extent of pancreatic A cell differentiation. GO:2000227 negative regulation of pancreatic A cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000227 negative regulation of pancreatic alpha cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic A cell differentiation. GO:2000228 positive regulation of pancreatic A cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000228 positive regulation of pancreatic alpha cell differentiation Any process that activates or increases the frequency, rate or extent of pancreatic A cell differentiation. GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016628 Reactome:R-HSA-9661745|Reactome:R-HSA-9661726|EC:1.3.1.-|Reactome:R-HSA-4755572|Reactome:R-HSA-4419979 Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces NAD or NADP. GO:2000229 regulation of pancreatic stellate cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000229 Any process that modulates the frequency, rate or extent of pancreatic stellate cell proliferation. GO:0016629 12-oxophytodienoate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016629 RHEA:21888|EC:1.3.1.42|MetaCyc:12-OXOPHYTODIENOATE-REDUCTASE-RXN|KEGG_REACTION:R03401 8-[(1R,2R)-3-oxo-2-{(Z)-pent-2-enyl}cyclopentyl]octanoate:NADP+ 4-oxidoreductase activity|12-oxo-phytodienoic acid reductase activity|12-oxo-phytodienoate reductase activity Catalysis of the reaction: 8-[(1R,2R)-3-oxo-2-{(Z)-pent-2-en-1-yl}cyclopentyl]octanoate + NADP(+) = (15Z)-12-oxophyto-10,15-dienoate + H(+) + NADPH. GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016624 EC:1.2.4.- oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulphide as acceptor Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a disulfide. GO:0016625 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016625 EC:1.2.7.- oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulphur protein as acceptor Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces an iron-sulfur protein. GO:0016626 obsolete oxidoreductase activity, acting on the aldehyde or oxo group of donors, other acceptors biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016626 oxidoreductase activity, acting on the aldehyde or oxo group of donors, other acceptors OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces an acceptor other than NAD, NADP, oxygen, an iron-sulfur protein, disulphide or a cytochrome. GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016627 EC:1.3.-.-|Reactome:R-HSA-2995334|Reactome:R-HSA-9661710 oxidoreductase activity, acting on the CH-CH group of donors, other acceptors Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. GO:2000220 regulation of pseudohyphal growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000220 Any process that modulates the frequency, rate or extent of pseudohyphal growth. GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016620 EC:1.2.1.-|Reactome:R-HSA-1222583 Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces NAD or NADP. GO:2000221 negative regulation of pseudohyphal growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000221 Any process that stops, prevents, or reduces the frequency, rate or extent of pseudohyphal growth. GO:0016621 cinnamoyl-CoA reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016621 MetaCyc:CINNAMOYL-COA-REDUCTASE-RXN|EC:1.2.1.44|RHEA:10620 cinnamoyl-CoA:NADPH reductase activity|cinnamoyl-coenzyme A reductase activity|p-hydroxycinnamoyl coenzyme A reductase activity|feruloyl coenzyme A reductase activity|cinnamaldehyde:NADP+ oxidoreductase (CoA-cinnamoylating)|feruloyl-CoA reductase activity|cinnamoyl CoA reductase activity|ferulyl-CoA reductase activity Catalysis of the reaction: cinnamaldehyde + CoA + NADP+ = cinnamoyl-CoA + NADPH + H+. GO:2000222 positive regulation of pseudohyphal growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000222 Any process that activates or increases the frequency, rate or extent of pseudohyphal growth. GO:0016622 oxidoreductase activity, acting on the aldehyde or oxo group of donors, cytochrome as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016622 EC:1.2.2.- Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a cytochrome. GO:2000223 regulation of BMP signaling pathway involved in heart jogging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000223 regulation of BMP signalling pathway involved in heart jogging pathway involved in somitogenesis Any process that modulates the frequency, rate or extent of BMP signaling pathway involved in heart jogging. GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016623 EC:1.2.3.- Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces oxygen. GO:2000224 regulation of testosterone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000224 Any process that modulates the frequency, rate or extent of testosterone biosynthetic process. CHEBI:31577 ethylenediamine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31577 GO:2000236 negative regulation of tRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000236 negative regulation of tRNA maturation Any process that stops, prevents, or reduces the frequency, rate or extent of tRNA processing. GO:2000237 positive regulation of tRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000237 positive regulation of tRNA maturation Any process that activates or increases the frequency, rate or extent of tRNA processing. GO:2000238 regulation of tRNA export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000238 regulation of tRNA export out of nucleus|regulation of tRNA-nucleus export|regulation of tRNA export from cell nucleus|regulation of tRNA transport from nucleus to cytoplasm Any process that modulates the frequency, rate or extent of tRNA export from nucleus. GO:2000239 negative regulation of tRNA export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000239 negative regulation of tRNA transport from nucleus to cytoplasm|negative regulation of tRNA-nucleus export|negative regulation of tRNA export out of nucleus|negative regulation of tRNA export from cell nucleus Any process that stops, prevents, or reduces the frequency, rate or extent of tRNA export from nucleus. GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016639 EC:1.4.1.- Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces NAD+ or NADP. GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016635 EC:1.3.5.- Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a quinone or related compound. GO:0016636 oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016636 EC:1.3.7.- oxidoreductase activity, acting on the CH-CH group of donors, iron-sulphur protein as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces an iron-sulfur protein. GO:2000230 negative regulation of pancreatic stellate cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000230 Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic stellate cell proliferation. GO:0016637 obsolete oxidoreductase activity, acting on the CH-CH group of donors, other acceptors biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016637 oxidoreductase activity, acting on the CH-CH group of donors, other acceptors OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces an acceptor other than quinone or related compound, a cytochrome, an iron-sulfur protein, NAD, NADP or oxygen. GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016638 EC:1.4.-.- oxidoreductase activity, acting on the CH-NH2 group of donors, other acceptors Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. GO:2000231 positive regulation of pancreatic stellate cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000231 Any process that activates or increases the frequency, rate or extent of pancreatic stellate cell proliferation. GO:2000232 regulation of rRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000232 regulation of 35S primary transcript processing Any process that modulates the frequency, rate or extent of rRNA processing. GO:0016631 enoyl-[acyl-carrier-protein] reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016631 MetaCyc:RXN1G-2527|EC:1.3.1.9|Wikipedia:Enoyl-acyl_carrier_protein_reductase|MetaCyc:1.3.1.39-RXN|MetaCyc:RXN1G-3613|MetaCyc:RXN1G-3667|MetaCyc:RXN1G-2544|MetaCyc:RXN1G-45|MetaCyc:RXN1G-3641|MetaCyc:RXN1G-3256|MetaCyc:1.3.1.10-RXN|MetaCyc:RXN1G-3993|MetaCyc:RXN1G-3232|MetaCyc:RXN1G-4140 acyl-ACP dehydrogenase activity|enoyl-acyl carrier protein reductase|enoyl-[acyl-carrier protein] reductase activity|enoyl-ACP reductase activity Catalysis of the reaction: acyl-[acyl-carrier protein] + NAD(P)+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NAD(P)H + H+. GO:2000233 negative regulation of rRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000233 negative regulation of 35S primary transcript processing Any process that stops, prevents, or reduces the frequency, rate or extent of rRNA processing. GO:0016632 oxidoreductase activity, acting on the CH-CH group of donors, cytochrome as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016632 EC:1.3.2.- Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a cytochrome. GO:0016633 galactonolactone dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016633 RHEA:32367|EC:1.3.2.3|MetaCyc:GALACTONOLACTONE-DEHYDROGENASE-RXN L-galactono-gamma-lactone:ferricytochrome-c oxidoreductase activity|L-galactono-1,4-lactone dehydrogenase activity|GLDHase activity|L-galactono-gamma-lactone dehydrogenase activity|L-galactono-1,4-lactone:ferricytochrome-c oxidoreductase activity|GLDase activity|L-galactonolactone dehydrogenase activity Catalysis of the reaction: L-galactono-1,4-lactone + 2 ferricytochrome c = L-ascorbate + 2 ferrocytochrome c. GO:2000234 positive regulation of rRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000234 positive regulation of 35S primary transcript processing Any process that activates or increases the frequency, rate or extent of rRNA processing. GO:2000235 regulation of tRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000235 regulation of tRNA maturation Any process that modulates the frequency, rate or extent of tRNA processing. GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016634 EC:1.3.3.- Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces oxygen. CHEBI:55534 (R)-2-hydroxy-4-methylpentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55534 CHEBI:55535 (R)-2-hydroxy-4-methylpentanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_55535 GO:0016630 protochlorophyllide reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016630 EC:1.3.1.33|RHEA:11132|MetaCyc:RXN1F-10 protochlorophyllide photooxidoreductase activity|protochlorophyllide oxidoreductase activity|NADPH2-protochlorophyllide oxidoreductase activity|NADPH-protochlorophyllide oxidoreductase activity|chlorophyllide-a:NADP+ 7,8-oxidoreductase activity|NADPH-protochlorophyllide reductase activity Catalysis of the reaction: chlorophyllide a + NADP+ = protochlorophyllide + NADPH + H+. GO:2000247 positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000247 Any process that activates or increases the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape. GO:2000248 negative regulation of establishment or maintenance of neuroblast polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000248 negative regulation of establishment and/or maintenance of neuroblast cell polarity Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or maintenance of neuroblast polarity. GO:2000249 regulation of actin cytoskeleton reorganization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000249 regulation of actin cytoskeleton reorganisation|regulation of actin cytoskeleton remodeling Any process that modulates the frequency, rate or extent of actin cytoskeleton reorganization. GO:0016606 LYSP100-associated nuclear domain biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016606 LANDs A nuclear body that is enriched in the lymphoid cell-specific protein LYSp100B; LANDs are globular, electron-dense structures and are morphologically distinct from the annular structures characteristic of PML bodies. GO:0016607 nuclear speck biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016607 nuclear speckles|splicing speckle|speckle domain|speckle focus|nuclear speckle A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy. GO:0016608 growth hormone-releasing hormone activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016608 GHRF activity|GHRH activity The action characteristic of growth hormone-releasing hormone, any of a family of peptide hormones that act on the anterior pituitary to stimulate the secretion of growth hormone and exert a trophic effect on the gland. GO:0016609 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016609 GO:0016602 CCAAT-binding factor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016602 nuclear transcription factor Y complex|CBF complex|NF-Y transcription factor complex A heteromeric transcription factor complex that binds to the CCAAT-box upstream of promoters; functions as both an activator and a repressor, depending on its interacting cofactors. Typically trimeric consisting of NFYA, NFYB and NFYC subunits. In Saccharomyces, it activates the transcription of genes in response to growth in a nonfermentable carbon source and consists of four known subunits: HAP2, HAP3, HAP4 and HAP5. GO:0016603 glutaminyl-peptide cyclotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016603 EC:2.3.2.5|MetaCyc:GLUTAMINYL-PEPTIDE-CYCLOTRANSFERASE-RXN|RHEA:23652 glutaminyl-tRNA cyclotransferase activity|glutaminyl cyclase activity|L-glutaminyl-peptide gamma-glutamyltransferase (cyclizing)|glutaminyl-transfer ribonucleate cyclotransferase activity Catalysis of the reaction: L-glutaminyl-peptide = 5-oxoprolyl-peptide + NH3. GO:2000240 positive regulation of tRNA export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000240 positive regulation of tRNA export from cell nucleus|positive regulation of tRNA export out of nucleus|positive regulation of tRNA-nucleus export|positive regulation of tRNA transport from nucleus to cytoplasm Any process that activates or increases the frequency, rate or extent of tRNA export from nucleus. GO:2000241 regulation of reproductive process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000241 Any process that modulates the frequency, rate or extent of reproductive process. GO:0016604 nuclear body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016604 NIF_Subcellular:sao505137457 Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins. CHEBI:31550 epothilone B biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_31550 GO:2000242 negative regulation of reproductive process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000242 Any process that stops, prevents, or reduces the frequency, rate or extent of reproductive process. GO:0016605 PML body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016605 nuclear dot|PML NB|ND10|PML nuclear body A class of nuclear body; they react against SP100 auto-antibodies (PML, promyelocytic leukemia); cells typically contain 10-30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection. GO:2000243 positive regulation of reproductive process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000243 Any process that activates or increases the frequency, rate or extent of reproductive process. GO:2000244 regulation of FtsZ-dependent cytokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000244 regulation of prokaryotic fission|regulation of prokaryote-type cytokinesis Any process that modulates the frequency, rate or extent of FtsZ-dependent cytokinesis. GO:2000245 negative regulation of FtsZ-dependent cytokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000245 negative regulation of prokaryotic fission|negative regulation of prokaryote-type cytokinesis Any process that stops, prevents, or reduces the frequency, rate or extent of Ftsz-dependent cytokinesis. GO:0016600 flotillin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016600 A protein complex that contains flotillin-1 and flotillin-2, and may contain associated proteins. Flotillins associate into membrane microdomains resembling caveolae. GO:2000246 positive regulation of FtsZ-dependent cytokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000246 positive regulation of prokaryotic fission|positive regulation of prokaryote-type cytokinesis Any process that activates or increases the frequency, rate or extent of Ftsz-dependent cytokinesis. GO:0016601 Rac protein signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016601 Rac mediated signal transduction A series of molecular signals within the cell that are mediated by a member of the Rac family of proteins switching to a GTP-bound active state. CHEBI:55517 trichothecene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_55517 CHEBI:55514 laminaritriose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_55514 CHEBI:80536 juvenile hormone III acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_80536 GO:2000258 negative regulation of protein activation cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000258 negative regulation of protein activation pathway|negative regulation of protein activitory cascade Any process that stops, prevents or reduces the frequency, rate or extent of protein activation cascade. GO:2000259 positive regulation of protein activation cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000259 positive regulation of protein activitory cascade|positive regulation of protein activation pathway Any process that activates or increases the frequency, rate or extent of protein activation cascade. CHEBI:80535 methyl farnesoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_80535 GO:0016617 4-oxoproline reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016617 MetaCyc:4-OXOPROLINE-REDUCTASE-RXN|RHEA:13601|EC:1.1.1.104 hydroxyproline oxidase activity|4-hydroxy-L-proline:NAD+ oxidoreductase activity|hydroxy-L-proline oxidase activity Catalysis of the reaction: 4-hydroxy-L-proline + NAD+ = 4-oxoproline + NADH + H+. GO:0016618 hydroxypyruvate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016618 MetaCyc:HYDROXYPYRUVATE-REDUCTASE-RXN|EC:1.1.1.81|RHEA:18657|MetaCyc:RXN0-300 beta-hydroxypyruvate reductase activity|D-glycerate dehydrogenase activity|D-glycerate:NADP+ 2-oxidoreductase activity|NADH:hydroxypyruvate reductase activity Catalysis of the reaction: D-glycerate + NADP+ = hydroxypyruvate + NADPH + H+. GO:0016619 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016619 GO:2000250 negative regulation of actin cytoskeleton reorganization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000250 negative regulation of actin cytoskeleton reorganisation|negative regulation of actin cytoskeleton remodeling Any process that stops, prevents, or reduces the frequency, rate or extent of actin cytoskeleton reorganization. GO:0016613 vanadium-iron nitrogenase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016613 vanadium-iron nitrogenase activity An enzyme complex containing a vanadium-iron cluster found in some species, such as Azotobacter vinelandii. It is composed of two proteins, dinitrogenase and nitrogenase reductase; dinitrogenase, the vanadium-iron protein, is tetrameric with an alpha2-beta2 structure, and nitrogenase reductase is a homodimer. GO:0016614 oxidoreductase activity, acting on CH-OH group of donors biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016614 EC:1.1.-.-|Reactome:R-HSA-1500781 oxidoreductase activity, acting on the CH-OH group of donors, other acceptors Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. GO:2000251 positive regulation of actin cytoskeleton reorganization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000251 positive regulation of actin cytoskeleton reorganisation|positive regulation of actin cytoskeleton remodeling Any process that activates or increases the frequency, rate or extent of actin cytoskeleton reorganization. GO:2000252 negative regulation of feeding behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000252 negative regulation of drinking|negative regulation of eating|negative regulation of feeding behaviour|negative regulation of behavioural response to food|negative regulation of behavioral response to food Any process that stops, prevents or reduces the frequency, rate or extent of feeding behavior. GO:0016615 malate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016615 Catalysis of the reversible conversion of pyruvate or oxaloacetate to malate. GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016616 Reactome:R-HSA-975629|EC:1.1.1.- glycolate reductase|NADH-dependent glyoxylate reductase|glyoxylic acid reductase Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP. GO:2000253 positive regulation of feeding behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000253 positive regulation of feeding behaviour|positive regulation of eating|positive regulation of drinking|positive regulation of behavioural response to food|positive regulation of behavioral response to food Any process that activates or increases the frequency, rate or extent of feeding behavior. UBERON:0008713 pectoral girdle and thoracic body wall skeletal muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008713 GO:2000254 regulation of male germ cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000254 Any process that modulates the frequency, rate or extent of male germ cell proliferation. GO:0016610 nitrogenase complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0016610 An enzyme complex composed of two proteins, dinitrogenase and nitrogenase reductase; dinitrogenase is tetrameric with an alpha2-beta2 structure and nitrogenase reductase is a homodimer, and both are associated with metal ions, which differ between species. Both proteins are required for the enzyme activity of the complex, the formation of oxidized ferredoxin and ammonia from reduced ferredoxin and nitrogen. UBERON:0008715 muscle tissue of prostate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008715 prostatic musclular tissue|prostate gland muscle tissue|prostate muscle tissue|prostatic muscle A muscle tissue that is part of a prostate gland. GO:2000255 negative regulation of male germ cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000255 Any process that stops, prevents or reduces the frequency, rate or extent of male germ cell proliferation. GO:0016611 iron-iron nitrogenase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016611 An enzyme complex containing an iron-iron cluster found in species such as the photosynthetic bacterium Rhodobacter capsulatus. It is composed of two main subunits, dinitrogenase and nitrogenase reductase. Dinitrogenase, the iron-iron containing subunit, has an alpha1-beta2 or alpha2-beta2 structure, and the nitrogenase reductase subunit is a homodimer. Functions in the catalysis of the formation of oxidized ferredoxin and ammonia from reduced ferredoxin and nitrogen. GO:2000256 positive regulation of male germ cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000256 Any process that activates or increases the frequency, rate or extent of male germ cell proliferation. GO:2000257 regulation of protein activation cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000257 regulation of protein activation pathway|regulation of protein activitory cascade Any process that modulates the frequency, rate or extent of protein activation cascade. GO:0016612 molybdenum-iron nitrogenase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016612 molybdenum-iron nitrogenase activity An enzyme complex containing a molybdenum-iron cluster found in many species. It is composed of two proteins, dinitrogenase and nitrogenase reductase; dinitrogenase, the molybdenum-iron protein, is tetrameric with an alpha2-beta2 structure, and nitrogenase reductase is a homodimer. CHEBI:55513 2-deoxy-D-ribofuranose 5-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55513 RO:0011002 regulates activity of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0011002 RO:0011002 The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B. CHEBI:55505 1,2-benzisothiazole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55505 CHEBI:80545 indolylmethyl desulfoglucosinolate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_80545 UBERON:0008789 cranial fossa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008789 Any of the three large depressions in the posterior, middle, and anterior aspects of the floor of the cranial cavity UBERON:0008780 inner cell mass derived epiblast biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008780 embryonic epiblast An embryonic structure that is derived from the inner cell mass and lies above the hypoblast and gives rise to the three primary germ layers UBERON:0008781 blastodisc derived epiblast biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008781 An epiblast (generic) that develops_from a blastodisc. UBERON:0008783 dorsal venous arch biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008783 arcus venosus dorsalis pedis|arcus venosus dorsalis pedis|dorsal venous arch of foot The dorsal venous arch of the foot is a superficial vein that connects the small saphenous vein and the great saphenous vein. Anatomically, it is defined by where the dorsal veins of the first and fifth digit, respectively, meet the great saphenous vein and small saphenous vein. UBERON:0008784 lower limb segment biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008784 free lower limb subdivision|subdivision of free lower limb|segment of free lower limb|free lower limb segment A limb segment that is part of a hindlimb. UBERON:0008785 upper limb segment biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008785 free upper limb subdivision|subdivision of free upper limb|segment of free upper limb|free upper limb segment A limb segment that is part of a forelimb. CHEBI:31549 epothilone A biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_31549 UBERON:0008772 proximal epiphysis of tibia biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008772 upper end of tibia|head of tibia|proximal end of tibia|proximal tibial epiphysis A proximal epiphysis that is part of a tibia. UBERON:0008775 proximal epiphysis of fibula biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008775 fibular head|head of fibula|upper end of fibula|caput fibulae|proximal end of fibula A proximal epiphysis that is part of a fibula. GO:2000203 regulation of ribosomal large subunit export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000203 regulation of ribosomal large subunit export from cell nucleus|regulation of ribosomal large subunit transport from nucleus to cytoplasm|regulation of ribosomal large subunit export out of nucleus|regulation of ribosomal large subunit-nucleus export|regulation of 60S ribosomal subunit export from nucleus|regulation of 50S ribosomal subunit export from nucleus Any process that modulates the frequency, rate or extent of ribosomal large subunit export from nucleus. GO:2000204 negative regulation of ribosomal large subunit export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000204 negative regulation of ribosomal large subunit export out of nucleus|negative regulation of 60S ribosomal subunit export from nucleus|negative regulation of 50S ribosomal subunit export from nucleus|negative regulation of ribosomal large subunit-nucleus export|negative regulation of ribosomal large subunit transport from nucleus to cytoplasm|negative regulation of ribosomal large subunit export from cell nucleus Any process that stops, prevents, or reduces the frequency, rate or extent of ribosomal large subunit export from nucleus. GO:2000205 positive regulation of ribosomal large subunit export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000205 positive regulation of ribosomal large subunit export from cell nucleus|positive regulation of 60S ribosomal subunit export from nucleus|positive regulation of 50S ribosomal subunit export from nucleus|positive regulation of ribosomal large subunit transport from nucleus to cytoplasm|positive regulation of ribosomal large subunit-nucleus export|positive regulation of ribosomal large subunit export out of nucleus Any process that activates or increases the frequency, rate or extent of ribosomal large subunit export from nucleus. GO:2000206 regulation of ribosomal small subunit export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000206 regulation of ribosomal small subunit-nucleus export|regulation of ribosomal small subunit export out of nucleus|regulation of ribosomal small subunit export from cell nucleus|regulation of ribosomal small subunit transport from nucleus to cytoplasm|regulation of 40S ribosomal subunit export from nucleus|regulation of 30S ribosomal subunit export from nucleus Any process that modulates the frequency, rate or extent of ribosomal small subunit export from nucleus. GO:2000207 negative regulation of ribosomal small subunit export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000207 negative regulation of ribosomal small subunit export from cell nucleus|negative regulation of 40S ribosomal subunit export from nucleus|negative regulation of ribosomal small subunit transport from nucleus to cytoplasm|negative regulation of 30S ribosomal subunit export from nucleus|negative regulation of ribosomal small subunit export out of nucleus|negative regulation of ribosomal small subunit-nucleus export Any process that stops, prevents, or reduces the frequency, rate or extent of ribosomal small subunit export from nucleus. GO:2000208 positive regulation of ribosomal small subunit export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000208 positive regulation of ribosomal small subunit transport from nucleus to cytoplasm|positive regulation of 40S ribosomal subunit export from nucleus|positive regulation of 30S ribosomal subunit export from nucleus|positive regulation of ribosomal small subunit export from cell nucleus|positive regulation of ribosomal small subunit export out of nucleus|positive regulation of ribosomal small subunit-nucleus export Any process that activates or increases the frequency, rate or extent of ribosomal small subunit export from nucleus. GO:2000209 regulation of anoikis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000209 regulation of suspension induced apoptosis|regulation of detachment induced cell death Any process that modulates the frequency, rate or extent of anoikis. GO:2000200 regulation of ribosomal subunit export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000200 regulation of ribosomal subunit transport from nucleus to cytoplasm|regulation of ribosomal subunit export from cell nucleus|regulation of ribosomal subunit export out of nucleus|regulation of ribosome export from nucleus|regulation of ribosomal subunit-nucleus export Any process that modulates the frequency, rate or extent of ribosomal subunit export from nucleus. GO:2000201 negative regulation of ribosomal subunit export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000201 negative regulation of ribosome export from nucleus|negative regulation of ribosomal subunit transport from nucleus to cytoplasm|negative regulation of ribosomal subunit-nucleus export|negative regulation of ribosomal subunit export out of nucleus|negative regulation of ribosomal subunit export from cell nucleus Any process that stops, prevents, or reduces the frequency, rate or extent of ribosomal subunit export from nucleus. GO:2000202 positive regulation of ribosomal subunit export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000202 positive regulation of ribosomal subunit export from cell nucleus|positive regulation of ribosomal subunit transport from nucleus to cytoplasm|positive regulation of ribosome export from nucleus|positive regulation of ribosomal subunit-nucleus export|positive regulation of ribosomal subunit export out of nucleus Any process that activates or increases the frequency, rate or extent of ribosomal subunit export from nucleus. GO:2000214 regulation of proline metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000214 regulation of proline metabolism Any process that modulates the frequency, rate or extent of proline metabolic process. GO:2000215 negative regulation of proline metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000215 negative regulation of proline metabolism Any process that stops, prevents, or reduces the frequency, rate or extent of proline metabolic process. GO:2000216 positive regulation of proline metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000216 positive regulation of proline metabolism Any process that activates or increases the frequency, rate or extent of proline metabolic process. GO:2000217 regulation of invasive growth in response to glucose limitation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000217 regulation of colony morphology Any process that modulates the frequency, rate or extent of invasive growth in response to glucose limitation. GO:2000218 negative regulation of invasive growth in response to glucose limitation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000218 negative regulation of colony morphology Any process that stops, prevents, or reduces the frequency, rate or extent of invasive growth in response to glucose limitation. GO:2000219 positive regulation of invasive growth in response to glucose limitation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000219 positive regulation of colony morphology Any process that activates or increases the frequency, rate or extent of invasive growth in response to glucose limitation. CHEBI:31529 ecgonine methyl ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31529 GO:2000210 positive regulation of anoikis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000210 positive regulation of detachment induced cell death|positive regulation of suspension induced apoptosis Any process that activates or increases the frequency, rate or extent of anoikis. GO:2000211 regulation of glutamate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000211 regulation of glutamic acid metabolism|regulation of glutamic acid metabolic process|regulation of glutamate metabolism Any process that modulates the frequency, rate or extent of glutamate metabolic process. GO:2000212 negative regulation of glutamate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000212 negative regulation of glutamate metabolism|negative regulation of glutamic acid metabolic process|negative regulation of glutamic acid metabolism Any process that stops, prevents, or reduces the frequency, rate or extent of glutamate metabolic process. GO:2000213 positive regulation of glutamate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000213 positive regulation of glutamate metabolism|positive regulation of glutamic acid metabolic process|positive regulation of glutamic acid metabolism Any process that activates or increases the frequency, rate or extent of glutamate metabolic process. GO:0002067 glandular epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002067 The process in which a relatively unspecialized cell acquires specialized features of a glandular epithelial cell. A glandular epithelial cell is a columnar/cuboidal epithelial cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland. GO:0002068 glandular epithelial cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002068 The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland. GO:0002069 columnar/cuboidal epithelial cell maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002069 The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell to attain its fully functional state. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube. GO:0002063 chondrocyte development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002063 The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate. GO:0002064 epithelial cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002064 The process whose specific outcome is the progression of an epithelial cell over time, from its formation to the mature structure. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface. GO:0002065 columnar/cuboidal epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002065 The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube. GO:0002066 columnar/cuboidal epithelial cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002066 The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell over time, from its formation to the mature structure. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube. GO:0002060 purine nucleobase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0002060 purine base binding|purine binding Interacting selectively and non-covalently with a purine nucleobase, an organic nitrogenous base with a purine skeleton. GO:0002061 pyrimidine nucleobase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0002061 pyrimidine base binding|pyrimidine binding|1,3-diazine binding Interacting selectively and non-covalently with a pyrimidine nucleobase, an organic nitrogenous base with a pyrimidine skeleton. GO:0002062 chondrocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002062 The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage. GO:0002078 membrane fusion involved in acrosome reaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002078 membrane fusion involved in the acrosomal reaction The fusion of the plasma membrane of the sperm with the outer acrosomal membrane. GO:0002079 inner acrosomal membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0002079 The acrosomal membrane region that underlies the acrosomal vesicle and is located toward the sperm nucleus. This region is responsible for molecular interactions allowing the sperm to penetrate the zona pellucida and fuses with the egg plasma membrane. GO:0002074 extraocular skeletal muscle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002074 The process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. An example of this process is found in Mus musculus. GO:0002075 somitomeric trunk muscle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002075 The process whose specific outcome is the progression of the somitomeric trunk muscle over time, from its formation to the mature structure. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. An example of this process is found in Mus musculus. GO:0002076 osteoblast development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002076 The process whose specific outcome is the progression of an osteoblast over time, from its formation to the mature structure. Osteoblast development does not include the steps involved in committing a cranial neural crest cell or an osteoprogenitor cell to an osteoblast fate. An osteoblast is a cell that gives rise to bone. GO:0002077 acrosome matrix dispersal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002077 The proteolytic digestion of components in the acrosomal matrix that occurs as part of the acrosome reaction. The process can occur either in the cumulus oophorous facilitating the penetration of it by the sperm, or at the zona pellucida allowing the sperm to reach the plasma membrane of the egg where the inner acrosomal membrane of the sperm can interact with the egg plasma membrane. GO:0002070 epithelial cell maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002070 The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface. GO:0002071 glandular epithelial cell maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002071 The developmental process, independent of morphogenetic (shape) change, that is required for a glandular epithelial cell to attain its fully functional state. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland. GO:0002072 optic cup morphogenesis involved in camera-type eye development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002072 optic cup morphogenesis involved in camera-style eye development The invagination of the optic vesicle to form two-walled indentations, the optic cups, that will go on to form the retina. This process begins with the optic vesicle becoming a two-walled structure and its subsequent shape changes. It does not include the fate commitment of cells to become the pigmented retina and the neural retina. An example of this process is found in Mus musculus. GO:0002073 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0002073 GO:0002080 acrosomal membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0002080 The membrane that surrounds the acrosomal lumen. The acrosome is a special type of lysosome in the head of a spermatozoon that contains acid hydrolases and is concerned with the breakdown of the outer membrane of the ovum during fertilization. GO:0002049 pyoverdine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002049 The chemical reactions and pathways resulting in the formation of the siderochrome pyoverdine. GO:0002045 regulation of cell adhesion involved in intussusceptive angiogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002045 The process that modulates the frequency, rate or extent of attachment of a blood vessel endothelial cell to another cell or to the extracellular matrix involved in intussusceptive angiogenesis. GO:0002046 opsin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0002046 metarhodopsin binding Interacting selectively and non-covalently with an opsin, any of a group of hydrophobic, integral membrane glycoproteins located primarily in the disc membrane of rods or cones, involved in photoreception. GO:0002047 phenazine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002047 dibenzopyrazine biosynthesis|dibenzopyrazine biosynthetic process|acridizine biosynthetic process|acridizine biosynthesis|azophenylene biosynthetic process|azophenylene biosynthesis|dibenzo-p-diazine biosynthesis|dibenzo-p-diazine biosynthetic process The chemical reactions and pathways resulting in the formation of a phenazine antibiotic, a polycyclic pyrazine with two nitrogen atoms in the ring. GO:0002048 pyoverdine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002048 pyoverdine metabolism The chemical reactions and pathways involving the siderochrome pyoverdine. GO:0002041 intussusceptive angiogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002041 The formation of new blood vessels as a result of the insertion and extension of lumenal tissue pillars. GO:0002042 cell migration involved in sprouting angiogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002042 The orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels involved in sprouting angiogenesis. GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002043 blood vessel endothelial cell proliferation during sprouting angiogenesis The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population contributing to sprouting angiogenesis. GO:0002044 blood vessel endothelial cell migration involved in intussusceptive angiogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002044 The orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels during intussusceptive angiogenesis. GO:0002040 sprouting angiogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002040 The extension of new blood vessels from existing vessels into avascular tissues, this process includes the specialization of endothelial cells into leading tip and stalk cells, proliferation and migration of the endothelial cells and cell adhesion resulting in angiogenic sprout fusion or lumen formation. GO:0016686 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016686 GO:0016687 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016687 GO:0016688 L-ascorbate peroxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016688 EC:1.11.1.11|RHEA:22996|MetaCyc:L-ASCORBATE-PEROXIDASE-RXN ascorbate peroxidase activity|L-ascorbate:hydrogen-peroxide oxidoreductase activity|ascorbic acid peroxidase activity|L-ascorbic acid peroxidase activity|L-ascorbic acid-specific peroxidase activity Catalysis of the reaction: L-ascorbate + hydrogen peroxide = dehydroascorbate + 2 H2O. GO:0016689 manganese peroxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016689 EC:1.11.1.13|MetaCyc:MANGANESE-PEROXIDASE-RXN|RHEA:22776 peroxidase-M2|Mn(II):hydrogen-peroxide oxidoreductase activity|Mn-dependent (NADH-oxidizing) peroxidase activity|Mn-dependent peroxidase activity Catalysis of the reaction: 2 Mn2+ + 2 H+ + hydrogen peroxide = 2 Mn3+ + 2 H2O. GO:0016682 oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016682 EC:1.10.3.- laccase activity Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces oxygen. GO:0016683 obsolete oxidoreductase activity, acting on diphenols and related substances as donors, other acceptors biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016683 oxidoreductase activity, acting on diphenols and related substances as donors, other acceptors OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces an acceptor other than a cytochrome, NAD, NADP or oxygen. GO:0016684 oxidoreductase activity, acting on peroxide as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016684 EC:1.11.-.- Catalysis of an oxidation-reduction (redox) reaction in which the peroxide group acts as a hydrogen or electron acceptor. GO:0016685 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016685 GO:0016680 oxidoreductase activity, acting on diphenols and related substances as donors, NAD or NADP as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016680 EC:1.10.1.- Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces NAD or NADP. GO:0016681 obsolete oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016681 EC:1.10.2.- OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces a cytochrome. GO:0002056 cytosine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0002056 Interacting selectively and non-covalently with cytosine. GO:0002057 guanine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0002057 Interacting selectively and non-covalently with guanine. GO:0002058 uracil binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0002058 Interacting selectively and non-covalently with uracil. GO:0002059 thymine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0002059 Interacting selectively and non-covalently with thymine. GO:0002052 positive regulation of neuroblast proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002052 upregulation of neuroblast proliferation|stimulation of neuroblast proliferation|up-regulation of neuroblast proliferation|activation of neuroblast proliferation|up regulation of neuroblast proliferation Any process that activates or increases the rate of neuroblast proliferation. GO:0002053 positive regulation of mesenchymal cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002053 upregulation of mesenchymal cell proliferation|stimulation of mesenchymal cell proliferation|up-regulation of mesenchymal cell proliferation|activation of mesenchymal cell proliferation|up regulation of mesenchymal cell proliferation The process of activating or increasing the rate or extent of mesenchymal cell proliferation. Mesenchymal cells are loosely organized embryonic cells. GO:0002054 nucleobase binding biolink:MolecularActivity go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0002054 Interacting selectively and non-covalently with a nucleobase, any of a class of pyrmidines or purines, organic nitrogenous bases. GO:0002055 adenine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0002055 6-aminopurine binding Interacting selectively and non-covalently with adenine, a purine base. GO:0002050 pyoverdine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002050 The chemical reactions and pathways resulting in the breakdown of the siderochrome pyoverdine. GO:0002051 osteoblast fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002051 The commitment of mesenchymal cells to the specific cell fate of an osteoblast. An osteoblast is a bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone. GO:0016697 oxidoreductase activity, acting on hydrogen as donor, cytochrome as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016697 EC:1.12.2.- Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces a cytochrome. GO:0016698 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016698 GO:0016699 oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016699 EC:1.12.7.- oxidoreductase activity, acting on hydrogen as donor, iron-sulphur protein as acceptor Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces an iron-sulfur protein. GO:0016693 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016693 GO:0016694 obsolete bacterial catalase-peroxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016694 bacterial catalase-peroxidase activity OBSOLETE. (Was not defined before being made obsolete). GO:0016695 oxidoreductase activity, acting on hydrogen as donor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016695 EC:1.12.-.- oxidoreductase activity, acting on hydrogen as donor, other acceptors Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor. GO:0016696 oxidoreductase activity, acting on hydrogen as donor, NAD or NADP as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016696 EC:1.12.1.- Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces NAD or NADP. GO:0016690 diarylpropane peroxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016690 RHEA:30271|MetaCyc:DIARYLPROPANE-PEROXIDASE-RXN|EC:1.11.1.14 diarylpropane oxygenase activity|diarylpropane:oxygen,hydrogen-peroxide oxidoreductase (C-C-bond-cleaving)|lignin peroxidase activity|LiP activity|ligninase I activity|ligninase activity|1,2-bis(3,4-dimethoxyphenyl)propane-1,3-diol:hydrogen-peroxide oxidoreductase activity Catalysis of the reaction: (3,4-dimethoxyphenyl)methanol + H2O2 = 3,4-dimethoxybenzaldehyde + 2 H2O. GO:0016691 chloride peroxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016691 EC:1.11.1.10|MetaCyc:CHLORIDE-PEROXIDASE-RXN flavin-heme chloroperoxidase activity|haem chloroperoxidase activity|cofactor-free chloroperoxidase activity|vanadium chloroperoxidase activity|chloride:hydrogen-peroxide oxidoreductase|chloroperoxidase activity|heme chloroperoxidase activity|flavin-haem chloroperoxidase activity Catalysis of the reaction: 2 R-H + 2 chloride + hydrogen peroxide = 2 R-Cl + 2 H2O. GO:0016692 NADH peroxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016692 KEGG_REACTION:R00090|EC:1.11.1.1|MetaCyc:NADH-PEROXIDASE-RXN|RHEA:18509 diphosphopyridine nucleotide peroxidase activity|nicotinamide adenine dinucleotide peroxidase activity|NAD peroxidase activity|NADH:hydrogen-peroxide oxidoreductase activity|NADH-peroxidase activity|DPNH peroxidase activity Catalysis of the reaction: H(2)O(2) + H(+) + NADH = 2 H(2)O + NAD(+). GO:0002027 regulation of heart rate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002027 regulation of rate of heart contraction|cardiac chronotropy|regulation of heart contraction rate Any process that modulates the frequency or rate of heart contraction. GO:0002028 regulation of sodium ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002028 regulation of Na+ transport|regulation of sodium transport Any process that modulates the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0002029 desensitization of G protein-coupled receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002029 desensitization of G-protein coupled receptor protein signaling pathway|desensitisation of G-protein coupled receptor protein signalling pathway The process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway after prolonged stimulation with an agonist of the pathway. GO:0002023 reduction of food intake in response to dietary excess biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002023 An eating behavior process whereby detection of a dietary excess results in a decrease in intake of nutrients. GO:0002024 diet induced thermogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002024 The process that results in increased metabolic rate in tissues of an organism. It is triggered by the detection of dietary excess. This process is achieved via signalling in the sympathetic nervous system. GO:0002025 norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure|noradrenaline-adrenaline vasodilation involved in regulation of blood pressure|norepinephrine-epinephrine vasodilation during blood pressure regulation A process that results in an increase in the diameter of an artery during the norepinephrine-epinephrine response to blood pressure change. GO:0002026 regulation of the force of heart contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002026 heart inotropy|cardiac inotropy Any process that modulates the extent of heart contraction, changing the force with which blood is propelled. GO:2000269 regulation of fibroblast apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000269 regulation of fibroblast apoptosis Any process that modulates the frequency, rate or extent of fibroblast apoptotic process. GO:0002020 protease binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0002020 Reactome:R-HSA-1297354 Interacting selectively and non-covalently with any protease or peptidase. GO:0002021 response to dietary excess biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002021 The physiological process in which dietary excess is sensed by the central nervous system, resulting in a reduction in food intake and increased energy expenditure. GO:0002022 detection of dietary excess biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002022 The neurological process in which the brain senses excessive caloric intake. GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016668 EC:1.8.1.- oxidoreductase activity, acting on a sulfur group of donors, NAD or NADP as acceptor|oxidoreductase activity, acting on sulphur group of donors, NAD or NADP as acceptor|oxidoreductase activity, acting on NADH or NADPH, disulfide as acceptor|oxidoreductase activity, acting on NADH or NADPH, disulphide as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces NAD or NADP. GO:2000261 negative regulation of blood coagulation, common pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000261 Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation, common pathway. GO:2000262 positive regulation of blood coagulation, common pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000262 Any process that activates or increases the frequency, rate or extent of blood coagulation, common pathway. GO:0016669 oxidoreductase activity, acting on a sulfur group of donors, cytochrome as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016669 EC:1.8.2.- oxidoreductase activity, acting on sulphur group of donors, cytochrome as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces a cytochrome. GO:2000263 regulation of blood coagulation, extrinsic pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000263 Any process that modulates the frequency, rate or extent of blood coagulation, extrinsic pathway. GO:2000264 negative regulation of blood coagulation, extrinsic pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000264 Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation, extrinsic pathway. GO:0016664 oxidoreductase activity, acting on other nitrogenous compounds as donors, iron-sulfur protein as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016664 EC:1.7.7.- oxidoreductase activity, acting on other nitrogenous compounds as donors, iron-sulphur protein as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces an iron-sulfur protein. GO:2000265 positive regulation of blood coagulation, extrinsic pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000265 Any process that activates or increases the frequency, rate or extent of blood coagulation, extrinsic pathway. GO:0016665 obsolete oxidoreductase activity, acting on other nitrogenous compounds as donors, other acceptors biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016665 oxidoreductase activity, acting on other nitrogenous compounds as donors, other acceptors OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces an acceptor other than a cytochrome, an iron-sulfur protein, oxygen, NAD or NADP. GO:2000266 regulation of blood coagulation, intrinsic pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000266 Any process that modulates the frequency, rate or extent of blood coagulation, intrinsic pathway. GO:2000267 negative regulation of blood coagulation, intrinsic pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000267 Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation, intrinsic pathway. GO:0016666 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016666 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016667 EC:1.8.-.-|Reactome:R-HSA-2213240 oxidoreductase activity, acting on sulfur group of donors, other acceptors|oxidoreductase activity, acting on sulphur group of donors Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. GO:2000268 positive regulation of blood coagulation, intrinsic pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000268 Any process that activates or increases the frequency, rate or extent of blood coagulation, intrinsic pathway. GO:0016660 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016660 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016661 EC:1.7.-.- oxidoreductase activity, acting on other nitrogenous compounds as donors, other acceptors Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. GO:0016662 oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016662 EC:1.7.2.- Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces a cytochrome. GO:0016663 oxidoreductase activity, acting on other nitrogenous compounds as donors, oxygen as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016663 EC:1.7.3.- Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces oxygen. GO:2000260 regulation of blood coagulation, common pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000260 Any process that modulates the frequency, rate or extent of blood coagulation, common pathway. GO:0002038 positive regulation of L-glutamate import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002038 upregulation of L-glutamate uptake|up-regulation of L-glutamate import|activation of L-glutamate import|activation of L-glutamate uptake|positive regulation of L-glutamate import|up-regulation of L-glutamate uptake|upregulation of L-glutamate transport|activation of L-glutamate transport|up regulation of L-glutamate import|stimulation of L-glutamate transport|positive regulation of L-glutamate uptake|up regulation of L-glutamate transport|up regulation of L-glutamate uptake|positive regulation of L-glutamate transport|up-regulation of L-glutamate transport|upregulation of L-glutamate import Any process that activates or increases the frequency, rate or extent of L-glutamate import into a cell. GO:0002039 p53 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0002039 Interacting selectively and non-covalently with one of the p53 family of proteins. GO:0002034 maintenance of blood vessel diameter homeostasis by renin-angiotensin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002034 regulation of blood vessel size by renin-angiotensin|regulation of blood vessel diameter by renin-angiotensin|renin-angiotensin regulation of blood vessel size The process in which the diameter of a blood vessel is changed due to activity of the renin-angiotensin system. GO:0002035 brain renin-angiotensin system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002035 The process in which an angiotensin-mediated signaling system present in the brain regulates the force with which blood passes through the circulatory system. GO:0002036 regulation of L-glutamate import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002036 regulation of L-glutamate transport|regulation of L-glutamate import|regulation of L-glutamate uptake Any process that modulates the frequency, rate or extent of L-glutamate import into a cell. GO:0002037 negative regulation of L-glutamate import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002037 down regulation of L-glutamate uptake|negative regulation of L-glutamate import|down-regulation of L-glutamate import|down regulation of L-glutamate transport|regulation of L-glutamate import|negative regulation of L-glutamate uptake|down-regulation of L-glutamate uptake|downregulation of L-glutamate transport|downregulation of L-glutamate import|down regulation of L-glutamate import|inhibition of L-glutamate transport|inhibition of L-glutamate import|inhibition of L-glutamate uptake|downregulation of L-glutamate uptake|down-regulation of L-glutamate transport|negative regulation of L-glutamate transport Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamate import into a cell. GO:0002030 inhibitory G protein-coupled receptor phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002030 inhibitory G-protein coupled receptor phosphorylation The process that inhibits the signaling function of a G protein-coupled receptor by addition of a phosphate group to its third intracellular loop consensus site. GO:0002031 G protein-coupled receptor internalization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002031 G-protein coupled receptor internalization The process that results in the uptake of a G protein-coupled receptor into an endocytic vesicle. GO:0002032 desensitization of G protein-coupled receptor signaling pathway by arrestin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002032 arrestin mediated desensitization of G-protein coupled receptor protein signaling pathway|arrestin mediated desensitisation of G-protein coupled receptor protein signalling pathway|desensitization of G-protein coupled receptor protein signaling pathway by arrestin|arrestin-mediated desensitization of G-protein coupled receptor protein signaling pathway The process that inhibits the signaling function of a G protein-coupled receptor by uncoupling the receptor from its downstream G proteins. GO:0002033 angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002033 vasodilation by angiotensin involved in regulation of systemic arterial blood pressure The process that increases the diameter of a blood vessel via the renin-angiotensin system. GO:2000272 negative regulation of signaling receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000272 negative regulation of signalling receptor activity|negative regulation of receptor activity Any process that stops, prevents or reduces the frequency, rate or extent of a signaling receptor activity. GO:0016679 oxidoreductase activity, acting on diphenols and related substances as donors biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016679 EC:1.10.-.- oxidoreductase activity, acting on diphenols and related substances as donors, other acceptors Catalysis of an oxidation-reduction (redox) reaction in which a diphenol or related substance acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. GO:2000273 positive regulation of signaling receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000273 positive regulation of signalling receptor activity Any process that activates or increases the frequency, rate or extent of signaling receptor activity. GO:2000274 regulation of epithelial cell migration, open tracheal system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000274 regulation of tracheal cell migration|regulation of tracheal epithelial cell migration Any process that modulates the frequency, rate or extent of epithelial cell migration, open tracheal system. GO:2000275 regulation of oxidative phosphorylation uncoupler activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000275 regulation of uncoupling protein activity|regulation of mitochondrial uncoupling protein activity Any process that modulates the frequency, rate or extent of oxidative phosphorylation uncoupler activity. GO:0016675 oxidoreductase activity, acting on a heme group of donors biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016675 EC:1.9.-.- oxidoreductase activity, acting on heme group of donors, other acceptors|oxidoreductase activity, acting on haem group of donors Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000276 negative regulation of mitochondrial uncoupling protein activity|negative regulation of uncoupling protein activity Any process that stops, prevents or reduces the frequency, rate or extent of oxidative phosphorylation uncoupler activity. GO:0016676 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016676 EC:1.9.3.- oxidoreductase activity, acting on haem group of donors, oxygen as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces oxygen. GO:2000277 positive regulation of oxidative phosphorylation uncoupler activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000277 positive regulation of mitochondrial uncoupling protein activity|positive regulation of uncoupling protein activity Any process that activates or increases the frequency, rate or extent of oxidative phosphorylation uncoupler activity. GO:0016677 oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016677 EC:1.9.6.- oxidoreductase activity, acting on haem group of donors, nitrogenous group as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces a nitrogenous group. GO:2000278 regulation of DNA biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000278 regulation of DNA anabolism|regulation of DNA synthesis|regulation of DNA formation|regulation of DNA biosynthesis Any process that modulates the frequency, rate or extent of DNA biosynthetic process. GO:0016678 obsolete oxidoreductase activity, acting on heme group of donors, other acceptors biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016678 oxidoreductase activity, acting on haem group of donors, other acceptors|oxidoreductase activity, acting on heme group of donors, other acceptors OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces an acceptor other than a nitrogenous group or oxygen. GO:2000279 negative regulation of DNA biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000279 negative regulation of DNA biosynthesis|negative regulation of DNA anabolism|negative regulation of DNA synthesis|negative regulation of DNA formation Any process that stops, prevents or reduces the frequency, rate or extent of DNA biosynthetic process. GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016671 EC:1.8.4.- oxidoreductase activity, acting on sulphur group of donors, disulphide as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces disulfide. GO:0016672 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016672 EC:1.8.5.- oxidoreductase activity, acting on sulphur group of donors, quinone or similar compound as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces quinone or a related compound. GO:0016673 oxidoreductase activity, acting on a sulfur group of donors, iron-sulfur protein as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016673 EC:1.8.7.- oxidoreductase activity, acting on sulphur group of donors, iron-sulphur protein as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces an iron-sulfur protein. GO:0016674 obsolete oxidoreductase activity, acting on sulfur group of donors, other acceptors biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016674 oxidoreductase activity, acting on sulfur group of donors, other acceptors|oxidoreductase activity, acting on sulphur group of donors, other acceptors OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces an acceptor other than quinone or a related compound, oxygen, NAD, NADP, an iron-sulfur protein, disulfide or a cytochrome. GO:2000270 negative regulation of fibroblast apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000270 negative regulation of fibroblast apoptosis Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast apoptotic process. GO:2000271 positive regulation of fibroblast apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000271 positive regulation of fibroblast apoptosis Any process that activates or increases the frequency, rate or extent of fibroblast apoptotic process. GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016670 EC:1.8.3.- oxidoreductase activity, acting on sulphur group of donors, oxygen as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces oxygen. GO:0002005 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0002005 GO:0002006 vasoconstriction by vasopressin involved in systemic arterial blood pressure control biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002006 vasopressin mediated vasoconstriction involved in systemic arterial blood pressure control The decrease in blood vessel diameter as a result of the release of vasopressin into the blood stream. GO:0002007 detection of hypoxic conditions in blood by chemoreceptor signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002007 detection of hypoxic conditions in blood by chemoreceptor signalling The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies. GO:0002008 excitation of vasomotor center by chemoreceptor signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002008 excitation of vasomotor center by chemoreceptor signalling The process in which the molecular signal from the carotid and aortic bodies is relayed to the vasomotor center, causing it to signal an increase arterial pressure. GO:0002001 renin secretion into blood stream biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002001 renin release into blood stream The regulated release of renin into the blood stream by juxtoglomerular cells. GO:0002002 regulation of angiotensin levels in blood biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002002 control of blood angiotensin level|regulation of blood angiotensin level|control of angiotensin levels in blood The process that modulates the level of any of the various angiotensinogen proteolytic products in the blood. This occurs by the proteolytic cleavage of angiotensinogen, and its proteolytic products, to create a variety of active peptide hormones, such as angiotensin I and angiotensin II, as well as through the removal of these peptides from the circulation. GO:0002003 angiotensin maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002003 angiotensin catabolic process in blood The process leading to the attainment of the full functional capacity of angiotensin by conversion of angiotensinogen into mature angiotensin in the blood. GO:0002004 secretion of vasopressin involved in fast regulation of systemic arterial blood pressure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002004 secretion of vasopressin during fast control of blood pressure|secretion of vasopressin during fast regulation of systemic arterial blood pressure The regulated release of the hormone vasopressin into the blood stream by the hypothalamus and pituitary gland contributing to fast regulation of blood pressure. GO:0002000 detection of renal blood flow biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002000 The process in which the juxtaglomerular cells of the kidneys receive information about the amount of blood flowing through the arterioles and converts the information to a molecular signal. GO:2000283 negative regulation of cellular amino acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000283 negative regulation of cellular amino acid anabolism|negative regulation of amino acid biosynthetic process|negative regulation of cellular amino acid synthesis|negative regulation of cellular amino acid formation|negative regulation of cellular amino acid biosynthesis Any process that stops, prevents or reduces the frequency, rate or extent of cellular amino acid biosynthetic process. GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016646 EC:1.5.1.- Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces NAD or NADP. GO:2000284 positive regulation of cellular amino acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000284 positive regulation of cellular amino acid biosynthesis|positive regulation of cellular amino acid synthesis|positive regulation of cellular amino acid formation|positive regulation of amino acid biosynthetic process|positive regulation of cellular amino acid anabolism Any process that activates or increases the frequency, rate or extent of cellular amino acid biosynthetic process. GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016647 EC:1.5.3.- Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces oxygen. GO:0016648 oxidoreductase activity, acting on the CH-NH group of donors, disulfide as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016648 EC:1.5.4.- oxidoreductase activity, acting on the CH-NH group of donors, disulphide as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces disulfide. GO:2000285 obsolete negative regulation of regulation of excitatory postsynaptic membrane potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000285 negative regulation of regulation of excitatory postsynaptic membrane potential|negative regulation of EPSP OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of regulation of excitatory postsynaptic membrane potential. GO:0016649 oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016649 EC:1.5.5.- Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces quinone or similar compound. GO:2000286 receptor internalization involved in canonical Wnt signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000286 receptor internalization involved in canonical Wnt-activated signaling pathway|receptor internalization involved in canonical Wnt receptor signaling pathway|receptor internalization involved in frizzled-1 receptor signaling pathway|receptor internalization involved in Wnt receptor signaling pathway through beta-catenin|receptor internalization involved in canonical Wnt receptor signalling pathway|receptor internalization involved in Wnt receptor signalling pathway through beta-catenin|receptor internalization involved in Wnt receptor signaling pathway via beta-catenin A receptor internalization process that contributes to canonical Wnt signaling pathway. GO:0016642 oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016642 EC:1.4.4.- oxidoreductase activity, acting on the CH-NH2 group of donors, disulphide as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a disulfide group. GO:2000287 positive regulation of myotome development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000287 Any process that activates or increases the frequency, rate or extent of myotome development. GO:0016643 oxidoreductase activity, acting on the CH-NH2 group of donors, iron-sulfur protein as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016643 EC:1.4.7.- oxidoreductase activity, acting on the CH-NH2 group of donors, iron-sulphur protein as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces an iron-sulfur protein. GO:2000288 positive regulation of myoblast proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000288 Any process that activates or increases the frequency, rate or extent of myoblast proliferation. GO:2000289 regulation of photoreceptor cell axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000289 regulation of photoreceptor cell axon pathfinding Any process that modulates the frequency, rate or extent of photoreceptor cell axon guidance. GO:0016644 obsolete oxidoreductase activity, acting on the CH-NH2 group of donors, other acceptors biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016644 oxidoreductase activity, acting on the CH-NH2 group of donors, other acceptors OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces an acceptor other than a cytochrome, disulfide, an iron-sulfur protein, NAD, NADP or oxygen. GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016645 EC:1.5.-.- oxidoreductase activity, acting on the CH-NH group of donors, other acceptors Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. GO:0016640 oxidoreductase activity, acting on the CH-NH2 group of donors, cytochrome as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016640 EC:1.4.2.- Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a cytochrome molecule. GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016641 EC:1.4.3.- Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces an oxygen molecule. GO:0002009 morphogenesis of an epithelium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002009 epithelium morphogenesis The process in which the anatomical structures of epithelia are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube. GO:2000280 regulation of root development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000280 Any process that modulates the frequency, rate or extent of root development. GO:2000281 regulation of histone H3-T3 phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000281 Any process that modulates the frequency, rate or extent of histone H3-T3 phosphorylation. GO:2000282 regulation of cellular amino acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000282 regulation of cellular amino acid biosynthesis|regulation of cellular amino acid anabolism|regulation of amino acid biosynthetic process|regulation of cellular amino acid synthesis|regulation of cellular amino acid formation Any process that modulates the frequency, rate or extent of cellular amino acid biosynthetic process. GO:0002016 regulation of blood volume by renin-angiotensin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002016 renin-angiotensin regulation of blood volume|renin-angiotensin control of body fluid levels The process in which the renin-angiotensin system controls the rate of fluid intake and output into the blood. GO:0002017 regulation of blood volume by renal aldosterone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002017 renal regulation of blood volume by aldosterone|aldosterone mediated regulation of blood volume|aldosterone mediated control of body fluids The process in which the hormone aldosterone decreases the rate of diuresis and natriuresis resulting in increased blood volume. GO:0002018 renin-angiotensin regulation of aldosterone production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002018 renin-angiotensin control of aldosterone production The process in which an increase in active angiotensin stimulates the adrenal cortices to secrete aldosterone. GO:0002019 regulation of renal output by angiotensin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002019 angiotensin-mediated regulation of renal output|angiotensin mediated control of renal output|angiotensin mediated regulation of renal output The process in which angiotensin directly modulates the rate of urine output by the kidney. GO:0002012 vasoconstriction of artery involved in chemoreceptor response to lowering of systemic arterial blood pressure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002012 A process that is triggered by vasomotor excitation and results in a decrease in the diameter of an artery during the chemoreceptor response to decreased blood pressure. GO:0002013 detection of carbon dioxide by vasomotor center biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002013 The process by a carbon dioxide stimulus is received and converted to a molecular signal by the vasomotor center of the central nervous system. GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002014 The vasoconstriction that is triggered by vasomotor excitation resulting from the detection of high carbon dioxide levels in the vasomotor center of the central nervous system. GO:0002015 regulation of systemic arterial blood pressure by atrial baroreceptor feedback biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002015 atrial control of blood pressure|atrial low pressure baroreceptor regulation of blood pressure|atrial baroreceptor regulation of systemic arterial blood pressure|atrial reflex A process that controls blood pressure by sensing the amount of stretch occurring in the atria. GO:0002010 excitation of vasomotor center by baroreceptor signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002010 excitation of vasomotor center by baroreceptor signalling The process in which the molecular signal from the arterial baroreceptors is relayed to the vasomotor center causing it to signal increase arterial pressure. GO:0002011 morphogenesis of an epithelial sheet biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002011 The process in which the anatomical structures of an epithelial sheet are generated and organized. An epithelial sheet is a flat surface consisting of closely packed epithelial cells. GO:0016657 oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016657 EC:1.6.6.- oxidoreductase activity, acting on NADH or NADPH, nitrogenous group as acceptor Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a nitrogenous group. GO:2000294 positive regulation of defecation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000294 Any process that activates or increases the frequency, rate or extent of defecation. GO:2000295 regulation of hydrogen peroxide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000295 regulation of hydrogen peroxide catabolism|regulation of H2O2 catabolic process|regulation of hydrogen peroxide removal|regulation of hydrogen peroxide degradation|regulation of hydrogen peroxide scavenging|regulation of hydrogen peroxide breakdown|regulation of detoxification of H2O2|regulation of H2O2 scavenging|regulation of detoxification of hydrogen peroxide Any process that modulates the frequency, rate or extent of hydrogen peroxide catabolic process. GO:0016658 obsolete oxidoreductase activity, acting on NADH or NADPH, flavin as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016658 oxidoreductase activity, acting on NADH or NADPH, flavin as acceptor OBSOLETE. (Was not defined before being made obsolete). GO:2000296 negative regulation of hydrogen peroxide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000296 negative regulation of hydrogen peroxide scavenging|negative regulation of H2O2 scavenging|negative regulation of detoxification of hydrogen peroxide|negative regulation of detoxification of H2O2|negative regulation of hydrogen peroxide removal|negative regulation of hydrogen peroxide degradation|negative regulation of hydrogen peroxide catabolism|negative regulation of H2O2 catabolic process|negative regulation of hydrogen peroxide breakdown Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide catabolic process. GO:0016659 obsolete oxidoreductase activity, acting on NADH or NADPH, other acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016659 oxidoreductase activity, acting on NADH or NADPH, other acceptor OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces an acceptor other than disulfide, a heme protein, NAD, NADP, a nitrogenous group, a quinone or similar compound or oxygen. GO:2000297 negative regulation of synapse maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000297 negative regulation of synaptic maturation Any process that stops, prevents or reduces the frequency, rate or extent of synapse maturation. GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000298 regulation of Rho-associated protein kinase activity|regulation of ROCK kinase activity Any process that modulates the frequency, rate or extent of Rho-dependent protein serine/threonine kinase activity. GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016653 EC:1.6.2.- oxidoreductase activity, acting on NADH or NADPH, haem protein as acceptor|oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a heme protein. GO:2000299 negative regulation of Rho-dependent protein serine/threonine kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000299 negative regulation of ROCK kinase activity|negative regulation of Rho-associated protein kinase activity Any process that stops, prevents or reduces the frequency, rate or extent of Rho-dependent protein serine/threonine kinase activity. GO:0016654 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016654 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016655 EC:1.6.5.- oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule. GO:0016656 monodehydroascorbate reductase (NADH) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016656 MetaCyc:1.6.5.4-RXN|EC:1.6.5.4|RHEA:14581 MDHA|ascorbate free radical reductase activity|semidehydroascorbate reductase activity|AFR|NADH:AFR oxidoreductase activity|SDA reductase activity|MDAsA reductase (NADPH)|ascorbate free-radical reductase activity|NADH:ascorbate radical oxidoreductase activity|NADH:monodehydroascorbate oxidoreductase activity|monodehydroascorbate reductase activity|NADH-semidehydroascorbate oxidoreductase activity|ascorbic free radical reductase activity|NADH:semidehydroascorbic acid oxidoreductase activity|AFR-reductase activity Catalysis of the reaction: NADH + H+ + 2 monodehydroascorbate = NAD+ + 2 ascorbate. GO:0016650 obsolete oxidoreductase activity, acting on the CH-NH group of donors, other acceptors biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016650 oxidoreductase activity, acting on the CH-NH group of donors, other acceptors OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces an acceptor other than quinone or similar compound, disulfide, NAD, NADP, oxygen or a flavin. GO:0016651 oxidoreductase activity, acting on NAD(P)H biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016651 Reactome:R-HSA-109343|EC:1.6.-.-|Reactome:R-HSA-8956458 oxidoreductase activity, acting on NADH or NADPH|NAD(P)H dehydrogenase|oxidoreductase activity, acting on NADH or NADPH, other acceptor Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. GO:0016652 oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016652 EC:1.6.1.- oxidoreductase activity, acting on NAD or NADPH, NAD or NADP as acceptor Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces NAD+ or NADP. GO:2000290 regulation of myotome development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000290 Any process that modulates the frequency, rate or extent of myotome development. CHEBI:55552 thymidine 3'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55552 GO:2000291 regulation of myoblast proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000291 Any process that modulates the frequency, rate or extent of myoblast proliferation. GO:2000292 regulation of defecation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000292 Any process that modulates the frequency, rate or extent of defecation. CHEBI:55550 dalnigrein beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_55550 GO:2000293 negative regulation of defecation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000293 Any process that stops, prevents or reduces the frequency, rate or extent of defecation. CHEBI:55551 dalnigrein biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55551 GO:0099137 altruistic, chimeric, non-reproductive fruiting body development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099137 fully co-operative, chimeric, non-reproductive fruiting body development Development of a chimeric, non-reproductive fruiting body in which cells of all genotypes have an equal chance of becoming a spore cell. GO:0110016 B-WICH complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0110016 IntAct:EBI-13952597 A chromatin remodeling complex that positively regulates histone H3 acetylation, in particular H3K9, by recruiting histone acetyltransferases to rDNA gene regions. Located in the nucleolus where it assembles on RNA Polymerase I (Pol I) and possibly on RNA Polymerase III (Pol III) promoter and coding regions during early G1 phase and activates the post-initiation phases of Pol I transcription. May also activate RNA Polymerase II (Pol II) gene transcription. In mammals, B-WICH contains the WICH complex core of BAZ1B and SMARCA5, additional protein subunits and possibly rRNAs. Although it contains several catalytic subunits it is not clear which functions are carried out by the complex itself. GO:2000904 regulation of starch metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000904 regulation of starch metabolism Any process that modulates the frequency, rate or extent of starch metabolic process. GO:2000905 negative regulation of starch metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000905 negative regulation of starch metabolism Any process that stops, prevents or reduces the frequency, rate or extent of starch metabolic process. GO:0099138 altruistic, chimeric sorocarp development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099138 fully co-operative, chimeric sorocarp development Development of a chimeric sorocarp in which cells of all genotypes have an equal chance of becoming a spore cell. GO:0110017 cap-independent translational initiation of linear mRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110017 The process where translation initiation recruits the 40S ribosomal subunits in a cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate linear mRNA translation. GO:2000906 positive regulation of starch metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000906 positive regulation of starch metabolism Any process that activates or increases the frequency, rate or extent of starch metabolic process. GO:0099135 chimeric colonial development biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0099135 Development a structure consisting of multiple co-operating unicellular organisms of the same species, involving cells of more that one genotype. GO:0110014 negative regulation of aggregation involved in sorocarp development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110014 Any process that decreases the frequency, rate or extent of aggregation involved in sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug. GO:0099136 chimeric non-reproductive fruiting body development biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0099136 Development of a non-reproductive fruiting body formed by aggregation of cells with different genotypes. GO:2000907 negative regulation of glucomannan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000907 negative regulation of glucomannan catabolism Any process that stops, prevents or reduces the frequency, rate or extent of glucomannan catabolic process. GO:0110015 positive regulation of elastin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110015 Any process that activates or increases the frequency, rate or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin. GO:0110012 protein localization to P-body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110012 protein localization to cytoplasmic mRNA processing body|protein localization to P body|protein localisation to P-body Any process in which a protein is transported to, or maintained at, a P-body. GO:0099133 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0099133 GO:2000908 positive regulation of glucomannan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000908 positive regulation of glucomannan catabolism Any process that activates or increases the frequency, rate or extent of glucomannan catabolic process. GO:2000909 regulation of sterol import biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000909 regulation of sterol influx|regulation of sterol uptake Any process that modulates the frequency, rate or extent of sterol import. GO:0110013 positive regulation of aggregation involved in sorocarp development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110013 Any process that increases the frequency, rate or extent of aggregation involved in sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug. GO:0099134 chimeric sorocarp development biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0099134 Development of a sorocarp formed by aggregation of cells with different genotypes. GO:0099131 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0099131 GO:0110010 basolateral protein secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110010 The controlled release of proteins from a cell at the sides which interface adjacent cells and near the base. GO:0110011 regulation of basement membrane organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110011 Any process that modulates the frequency, rate or extent of the assembly, disassembly or arrangement of constituent parts of the basement membrane. GO:0099132 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0099132 GO:0099130 estrogen binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0099130 Interacting selectively and non-covalently with any estrogen. GO:2000900 cyclodextrin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000900 cyclodextrin metabolism The chemical reactions and pathways involving a cyclodextrin. GO:2000901 cyclodextrin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000901 cyclodextrin catabolism The chemical reactions and pathways resulting in the breakdown of a cyclodextrin. GO:2000902 cellooligosaccharide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000902 cellooligosaccharide metabolism The chemical reactions and pathways involving a cellooligosaccharide. CHEBI:16739 2-furoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16739 GO:2000903 cellooligosaccharide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000903 cellooligosaccharide catabolism The chemical reactions and pathways resulting in the breakdown of a cellooligosaccharide. CHEBI:16737 creatinine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16737 CHEBI:16738 2,4-dichlorophenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16738 CHEBI:16735 2-acetamido-2-deoxy-3-O-(4-deoxy-alpha-L-threo-hex-4-enopyranosyluronic acid)-6-O-sulfo-D-glucopyranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16735 GO:0051191 prosthetic group biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051191 coenzyme and prosthetic group biosynthesis|coenzyme and prosthetic group biosynthetic process|prosthetic group anabolism|prosthetic group synthesis|prosthetic group formation|prosthetic group biosynthesis The chemical reactions and pathways resulting in the formation of a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein. CHEBI:16733 D-alpha-amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16733 GO:0051192 prosthetic group binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051192 Interacting selectively and non-covalently with a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein. CHEBI:16734 N-acetyl-D-tryptophan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16734 CHEBI:41701 (2S)-amino[(4R)-2-iminohexahydropyrimidin-4-yl]acetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_41701 CHEBI:16731 (E)-cinnamaldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16731 GO:0075160 obsolete positive regulation of G-protein alpha subunit-mediated signal transduction in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075160 positive regulation of symbiont G-protein alpha subunit-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its G-protein alpha subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075161 obsolete negative regulation of G-protein alpha subunit-mediated signal transduction in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075161 negative regulation of symbiont G-protein alpha subunit-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont G-protein alpha subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051190 prosthetic group catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051190 coenzyme and prosthetic group catabolism|prosthetic group breakdown|coenzyme and prosthetic group catabolic process|prosthetic group catabolism|prosthetic group degradation The chemical reactions and pathways resulting in the breakdown of a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein. CHEBI:16732 CDP-ethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16732 GO:0075162 obsolete regulation of G-protein beta subunit-mediated signal transduction in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075162 regulation of symbiont G-protein beta subunit-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its G-protein beta subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051195 obsolete negative regulation of cofactor metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051195 down-regulation of cofactor metabolic process|downregulation of cofactor metabolic process|negative regulation of cofactor metabolism|down regulation of cofactor metabolic process|inhibition of cofactor metabolic process OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a cofactor. GO:0051196 obsolete regulation of coenzyme metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051196 regulation of coenzyme and prosthetic group metabolic process|regulation of coenzyme and prosthetic group metabolism|regulation of coenzyme metabolism OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a coenzyme. CHEBI:16730 chloramphenicol 3-acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16730 GO:0075163 obsolete positive regulation of G-protein beta subunit-mediated signal transduction in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075163 positive regulation of symbiont G-protein beta subunit-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its G-protein beta subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051193 obsolete regulation of cofactor metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051193 regulation of cofactor metabolism OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a cofactor. GO:0075164 obsolete negative regulation of G-protein beta subunit-mediated signal transduction in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075164 negative regulation of symbiont G-protein beta subunit-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont G-protein beta subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075165 obsolete regulation of G-protein gamma subunit-mediated signal transduction in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075165 regulation of symbiont G-protein gamma subunit-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its G-protein gamma subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051194 obsolete positive regulation of cofactor metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051194 stimulation of cofactor metabolic process|up-regulation of cofactor metabolic process|activation of cofactor metabolic process|up regulation of cofactor metabolic process|positive regulation of cofactor metabolism|upregulation of cofactor metabolic process OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a cofactor. GO:0051199 regulation of prosthetic group metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051199 regulation of coenzyme and prosthetic group metabolic process|regulation of prosthetic group metabolism|regulation of coenzyme and prosthetic group metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a prosthetic group. GO:0075166 obsolete positive regulation of G-protein gamma subunit-mediated signal transduction in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075166 positive regulation of symbiont G-protein gamma subunit-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its G-protein gamma subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075167 obsolete negative regulation of G-protein gamma subunit-mediated signal transduction in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075167 negative regulation of symbiont G-protein gamma subunit-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont G-protein gamma subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051197 obsolete positive regulation of coenzyme metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051197 up regulation of coenzyme metabolic process|positive regulation of coenzyme metabolism|positive regulation of coenzyme and prosthetic group metabolic process|upregulation of coenzyme metabolic process|positive regulation of coenzyme and prosthetic group metabolism|stimulation of coenzyme metabolic process|up-regulation of coenzyme metabolic process|activation of coenzyme metabolic process OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a coenzyme. GO:0075168 obsolete regulation of protein kinase-mediated signal transduction in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075168 regulation of symbiont protein kinase-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its protein kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0110018 cap-independent translational initiation of circular RNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110018 cap-independent translational initiation of circRNA The process where translation initiation recruits the 40S ribosomal subunits in a cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate circRNA translation. GO:0099139 cheating during chimeric sorocarp development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099139 Any process during chimeric sorocarp development that increases by which a cell increases the number of spore cells sharing its genotype at the expense of cells of other genotypes. GO:0110019 IRES-dependent translational initiation of circular RNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110019 IRES-dependent translational initiation of circRNA The process where translation initiation recruits the 40S ribosomal subunits via an internal ribosome entry segment (IRES) before an AUG codon is encountered in an appropriate sequence context to initiate circular mRNA translation. GO:0051198 obsolete negative regulation of coenzyme metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051198 downregulation of coenzyme metabolic process|down regulation of coenzyme metabolic process|negative regulation of coenzyme metabolism|inhibition of coenzyme metabolic process|negative regulation of coenzyme and prosthetic group metabolism|negative regulation of coenzyme and prosthetic group metabolic process|down-regulation of coenzyme metabolic process OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a coenzyme. GO:0075169 obsolete positive regulation of symbiont protein kinase-mediated signal transduction in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075169 OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its protein kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0099148 regulation of synaptic vesicle docking biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099148 Any process that modulates the frequency, rate or extent of synaptic vesicle docking. GO:2000915 regulation of glucuronoxylan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000915 regulation of glucuronoxylan catabolism Any process that modulates the frequency, rate or extent of glucuronoxylan catabolic process. GO:0110027 negative regulation of DNA strand resection involved in replication fork processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110027 Any process that stops, prevents, or reduces the frequency, rate or extent of DNA strand resection involved in replication fork processing. GO:0075159 obsolete regulation of G-protein alpha subunit-mediated signal transduction in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075159 regulation of symbiont G-protein alpha subunit-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its G-protein alpha subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0099149 regulation of postsynaptic neurotransmitter receptor internalization biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099149 regulation of postsynaptic neurotransmitter receptor endocytosis Any process that modulates the frequency, rate or extent of endocytosis of neurotransmitter receptor at the postsynapse. GO:2000916 negative regulation of glucuronoxylan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000916 negative regulation of glucuronoxylan catabolism Any process that stops, prevents or reduces the frequency, rate or extent of glucuronoxylan catabolic process. GO:0110028 positive regulation of mitotic spindle organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110028 Any process that activates or increases the frequency, rate or extent of mitotic spindle organization. GO:2000917 positive regulation of glucuronoxylan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000917 positive regulation of glucuronoxylan catabolism Any process that activates or increases the frequency, rate or extent of glucuronoxylan catabolic process. GO:0110025 DNA strand resection involved in replication fork processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110025 The 5' to 3' exonucleolytic resection of DNA at the site of a stalled replication fork that contributes to replication fork processing. GO:0099146 intrinsic component of postsynaptic density membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099146 intrinsic to postsynaptic specialization membrane The component of the postsynaptic density membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0099147 extrinsic component of postsynaptic density membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099147 The component of the postsynaptic density membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:2000918 regulation of glucuronoarabinoxylan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000918 regulation of glucuronoarabinoxylan catabolism Any process that modulates the frequency, rate or extent of glucuronoarabinoxylan catabolic process. GO:0110026 regulation of DNA strand resection involved in replication fork processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110026 Any process that modulates the frequency, rate or extent of DNA strand resection involved in replication fork processing. GO:2000919 negative regulation of glucuronoarabinoxylan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000919 negative regulation of glucuronoarabinoxylan catabolism Any process that stops, prevents or reduces the frequency, rate or extent of glucuronoarabinoxylan catabolic process. GO:0110023 negative regulation of cardiac muscle myoblast proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110023 Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle myoblast proliferation. GO:0099144 anchored component of synaptic membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099144 The component of the synaptic membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. GO:0099145 regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099145 Any process that modulates the frequency, rate or extent of exocytic fusion of neurotransmitter receptor containing vesicles into the postsynaptic membrane. GO:0110024 positive regulation of cardiac muscle myoblast proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110024 Any process that activates or increases the frequency, rate or extent of cardiac muscle myoblast proliferation. GO:0110021 cardiac muscle myoblast proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110021 The multiplication or reproduction of cardiac muscle myoblasts, resulting in the expansion of a cardiac muscle myoblast cell population. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life. GO:0099142 intracellularly ATP-gated ion channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0099142 Enables the transmembrane transfer of an ion by a channel that opens when ATP has been bound by the channel complex or one of its constituent parts on the intracellular side of the plasma membrane. GO:0099143 presynaptic actin cytoskeleton biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099143 The actin cytoskeleton that is part of a presynapse. GO:0110022 regulation of cardiac muscle myoblast proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110022 Any process that modulates the frequency, rate or extent of cardiac muscle myoblast proliferation. GO:0099140 presynaptic actin cytoskeleton organization biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099140 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the presynaptic actin cytoskeleton. GO:0110020 regulation of actomyosin structure organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110020 Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. GO:0099141 cellular response to protozoan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099141 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a protozoan. GO:2000910 negative regulation of sterol import biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000910 negative regulation of sterol uptake|negative regulation of sterol influx Any process that stops, prevents or reduces the frequency, rate or extent of sterol import. GO:2000911 positive regulation of sterol import biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000911 positive regulation of sterol uptake|positive regulation of sterol influx Any process that activates or increases the frequency, rate or extent of sterol import. GO:2000912 regulation of galactoglucomannan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000912 regulation of galactoglucomannan catabolism Any process that modulates the frequency, rate or extent of galactoglucomannan catabolic process. CHEBI:16728 2-acyl-sn-glycero-3-phosphocholine(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16728 GO:2000913 negative regulation of galactoglucomannan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000913 negative regulation of galactoglucomannan catabolism Any process that stops, prevents or reduces the frequency, rate or extent of galactoglucomannan catabolic process. GO:2000914 positive regulation of galactoglucomannan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000914 positive regulation of galactoglucomannan catabolism Any process that activates or increases the frequency, rate or extent of galactoglucomannan catabolic process. CHEBI:16729 formyl dihydrogen phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16729 CHEBI:16727 3-maleylpyruvate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16727 CHEBI:16724 4-hydroxybutyrate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16724 CHEBI:16725 2,3-dihydroxy-p-cumic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16725 CHEBI:16723 4-methylthio-2-oxobutanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16723 GO:0075150 obsolete regulation of receptor-mediated signal transduction in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075150 regulation of symbiont receptor-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075151 obsolete positive regulation of receptor-mediated signal transduction in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075151 positive regulation of symbiont receptor-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075152 obsolete negative regulation of receptor-mediated signal transduction in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075152 negative regulation of symbiont receptor-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075153 obsolete regulation of transmembrane receptor-mediated signal transduction in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075153 regulation of symbiont transmembrane receptor-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its transmembrane receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075154 obsolete positive regulation of transmembrane receptor-mediated signal transduction in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075154 OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its transmembrane receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075155 obsolete negative regulation of transmembrane receptor-mediated signal transduction in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075155 negative regulation of symbiont transmembrane receptor-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont transmembrane receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075156 obsolete regulation of G protein-coupled receptor signaling pathway in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075156 regulation of G-protein coupled receptor protein signaling pathway in response to host|regulation of G-protein coupled receptor protein signalling pathway in response to host|regulation of symbiont G-protein coupled receptor protein-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its G protein-coupled receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0110029 negative regulation of meiosis I biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110029 Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells. GO:0075157 obsolete positive regulation of G protein-coupled receptor signaling pathway in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075157 positive regulation of G-protein coupled receptor protein signaling pathway in response to host|positive regulation of symbiont G-protein coupled receptor protein-mediated signal transduction in response to host|positive regulation of G-protein coupled receptor protein signalling pathway in response to host OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its G protein-coupled receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075158 obsolete negative regulation of G protein-coupled receptor signaling pathway in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075158 negative regulation of G-protein coupled receptor protein signaling pathway in response to host|negative regulation of symbiont G-protein coupled receptor protein-mediated signal transduction in response to host|negative regulation of G-protein coupled receptor protein signalling pathway in response to host OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont G protein-coupled receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0099115 chromosome, subtelomeric region biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0099115 SO:0001997 sub-telomeric heterochromatin|subtelomere|nuclear subtelomeric heterochromatin|subtelomeric heterochromatin A region of the chromosome, adjacent to the telomere (on the centromeric side) that contains repetitive DNA and sometimes genes. This region is usually heterochromatin. GO:2000926 positive regulation of cellodextrin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000926 positive regulation of cellodextrin metabolism Any process that activates or increases the frequency, rate or extent of cellodextrin metabolic process. GO:0110038 negative regulation of nematode male tail tip morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110038 Any process that stops, prevents, or reduces the frequency, rate or extent of nematode male tail tip morphogenesis. GO:0099116 tRNA 5'-end processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099116 tRNA 5' processing The process in which the 5' end of a pre-tRNA molecule is converted to that of a mature tRNA. GO:2000927 regulation of cellodextrin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000927 regulation of cellodextrin catabolism Any process that modulates the frequency, rate or extent of cellodextrin catabolic process. GO:0110039 positive regulation of nematode male tail tip morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110039 Any process that activates or increases the frequency, rate or extent of nematode male tail tip morphogenesis. GO:0099113 negative regulation of presynaptic cytosolic calcium concentration biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099113 Any process that decreases the concentration of calcium ions in the presynaptic cytosol. GO:0110036 C2 domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0110036 Interacting selectively and non-covalently with the C2 domain of a protein, a protein structural domain involved in targeting proteins to cell membranes. GO:2000928 negative regulation of cellodextrin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000928 negative regulation of cellodextrin catabolism Any process that stops, prevents or reduces the frequency, rate or extent of cellodextrin catabolic process. GO:0110037 regulation of nematode male tail tip morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110037 Any process that modulates the frequency, rate or extent of nematode male tail tip morphogenesis, the process in which the anatomical structure of the adult male tail tip is generated and organized. GO:2000929 positive regulation of cellodextrin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000929 positive regulation of cellodextrin catabolism Any process that activates or increases the frequency, rate or extent of cellodextrin catabolic process. GO:0099114 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0099114 GO:0110034 negative regulation of adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110034 negative regulation of adenylate cyclase-activating glucose-activated G-protein coupled receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway. GO:0099111 microtubule-based transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099111 A microtubule-based process that results in the transport of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules. GO:0110035 rDNA spacer replication fork barrier binding, bending biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0110035 The activity of binding selectively, and in a sequence-specific manner, a replication fork barrier found in rDNA spacers, and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence. GO:0099112 microtubule polymerization based protein transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099112 The transport of a protein driven by polymerization of a microtubule to which it is attached. GO:0110032 positive regulation of G2/MI transition of meiotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110032 Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle. GO:0110033 regulation of adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110033 regulation of adenylate cyclase-activating glucose-activated G-protein coupled receptor signaling pathway Any process that modulates the frequency, rate or extent of the adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway, the series of molecular signals generated as a consequence of glucose binding to a G protein-coupled receptor, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP). GO:0099110 microtubule polymerization based protein transport to cell tip cortex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099110 The transport of a protein to the cortex of the cell tip, driven by polymerization of a microtubule to which the protein is attached. GO:0110030 regulation of G2/MI transition of meiotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110030 Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle. GO:0110031 negative regulation of G2/MI transition of meiotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110031 Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle. GO:2000920 positive regulation of glucuronoarabinoxylan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000920 positive regulation of glucuronoarabinoxylan catabolism Any process that activates or increases the frequency, rate or extent of glucuronoarabinoxylan catabolic process. GO:2000921 regulation of arabinoxylan-containing compound catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000921 regulation of arabinoxylan catabolism Any process that modulates the frequency, rate or extent of arabinoxylan-containing compound catabolic process. GO:2000922 negative regulation of arabinoxylan-containing compound catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000922 negative regulation of arabinoxylan catabolism Any process that stops, prevents or reduces the frequency, rate or extent of arabinoxylan-containing compound catabolic process. GO:2000923 positive regulation of arabinoxylan-containing compound catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000923 positive regulation of arabinoxylan catabolism Any process that activates or increases the frequency, rate or extent of arabinoxylan-containing compound catabolic process. GO:2000924 regulation of cellodextrin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000924 regulation of cellodextrin metabolism Any process that modulates the frequency, rate or extent of cellodextrin metabolic process. GO:2000925 negative regulation of cellodextrin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000925 negative regulation of cellodextrin metabolism Any process that stops, prevents or reduces the frequency, rate or extent of cellodextrin metabolic process. CHEBI:16758 3-dehydrocarnitinium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16758 GO:0075180 regulation of transcription in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075180 regulation of symbiont transcription in response to host Any process in which the symbiont organism modulates the frequency, rate or extent of its transcription as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:16755 chenodeoxycholic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16755 GO:0075181 positive regulation of symbiont transcription in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075181 Any process in which an organism activates, maintains or increases the frequency, rate or extent of its transcription as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:16753 pantetheine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16753 GO:0075182 negative regulation of symbiont transcription in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075182 Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of its transcription as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:16754 4-carboxymethyl-3-methylbut-2-en-1,4-olide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16754 GO:0075183 infection cushion formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075183 infection cushion formation on or near host The process in which an organized mass of hyphae is formed and numerous infective hyphae develop from the hyphae mass. CHEBI:16751 inulobiose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16751 GO:0075184 regulation of infection cushion formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075184 regulation of infection cushion formation on or near host Any process that modulates the frequency, rate or extent of symbiont infection cushion formation. GO:0075185 positive regulation of infection cushion formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075185 positive regulation of infection cushion formation on or near host Any process that activates or increases the frequency, rate or extent of symbiont infection cushion formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:16752 erythro-5-phosphonooxy-L-lysine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16752 GO:0075186 negative regulation of infection cushion formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075186 negative regulation of infection cushion formation on or near host Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont infection cushion formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075187 hyphopodium formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075187 hyphopodium formation on or near host The process in which a specialized structure, consisted of stalked, thick-walled, lobed cells of vegetative epiphytic hyphae, is formed, to attach and penetrate the host surface. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:16750 guanosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16750 GO:0099119 3-demethylubiquinol-8 3-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0099119 Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinol-8 = S-adenosyl-L-homocysteine + ubiquinol-8. GO:0075188 regulation of hyphopodium formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075188 regulation of hyphopodium formation on or near host Any process that modulates the frequency, rate or extent of symbiont hyphopodium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075189 positive regulation of hyphopodium formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075189 positive regulation of hyphopodium formation on or near host Any process that activates or increases the frequency, rate or extent of symbiont hyphopodium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0099117 protein transport along microtubule to cell tip biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099117 The movement of a protein along a microtubule to the cell-tip, mediated by motor proteins. GO:0099118 microtubule-based protein transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099118 A microtubule-based process that results in the transport of proteins. GO:2000937 negative regulation of cellotriose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000937 negative regulation of cellotriose catabolism Any process that stops, prevents or reduces the frequency, rate or extent of cellotriose catabolic process. GO:0099126 transforming growth factor beta complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0099126 IntAct:EBI-12502440|IntAct:EBI-12502251|IntAct:EBI-12501958 TGF-beta complex|TGFbeta dimer|TGFbeta complex|TGFB dimer|TGFB complex|TGF-beta dimer A protein complex acting as ligand of the transforming growth factor beta receptor complex, typically a homodimer of any of the TFGbeta isoforms. The precursor of TGFbeta proteins is cleaved into mature TGFbeta and the latency-associated peptide (LAP), which remains non-covalently linked to mature TGFbeta rendering it inactive. TGFbeta is activated by dimerisation and dissociation of the LAP. GO:0099127 envenomation resulting in positive regulation of argininosuccinate synthase activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099127 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the activation of the cytosolic argininosuccinate synthase in the bitten organism. GO:2000938 positive regulation of cellotriose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000938 positive regulation of cellotriose catabolism Any process that activates or increases the frequency, rate or extent of cellotriose catabolic process. GO:2000939 regulation of plant-type cell wall cellulose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000939 regulation of plant-type cell wall polysaccharide breakdown Any process that modulates the frequency, rate or extent of plant-type cell wall cellulose catabolic process. GO:0099124 axonal dopamine secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099124 axonal DA release|axonal dopamine release The regulated release of dopamine from an axon. GO:0099125 PAK family kinase-Sog2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0099125 A protein kinase complex comprising a conserved PAK/GC/Ste20 family kinase, leucine rich repeat protein Sog2 family, which function as part of the cell shape network. GO:0110045 negative regulation of cell cycle switching, mitotic to meiotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110045 Any process that stops, prevents, or reduces the frequency, rate, or extent of mitotic to meiotic cell cycle switching, the process in which a cell switches cell cycle mode from mitotic to meiotic division. GO:0099122 RNA polymerase II C-terminal domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0099122 RNAP II C-terminal binding Interacting selectively and non-covalently with the C-terminal domain (CTD) of the largest subunit of RNA polymerase II. The CTD is comprised of repeats of a heptapeptide with the consensus sequence YSPTSPS. The number of repeats varies with the species and a minimum number of repeats is required for RNAP II function. GO:0110046 signal transduction involved in cell cycle switching, mitotic to meiotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110046 A signal transduction process that contributes to cell cycle switching, mitotic to meiotic cell cycle. GO:0099123 somato-dendritic dopamine secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099123 somatodendritic dopamine release|STD DA release|STD dopamine release The regulated release of dopamine from the somatodendritic compartment (cell body or dendrites) of a neuron. GO:0110043 positive regulation of pharynx morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110043 Any process that activates or increases the frequency, rate or extent of pharynx morphogenesis. GO:0099120 socially cooperative development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099120 socially co-operative development|colonial development Development a structure consisting of multiple co-operating unicellular organisms of the same species. Examples include sorocarp development in Dictystelia and co-operative colonial structures formed by Myxococcus xanthus for the purpose of predation and fruiting body formation. GO:0110044 regulation of cell cycle switching, mitotic to meiotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110044 Any process that modulates the frequency, rate, or extent of mitotic to meiotic cell cycle switching, the process in which a cell switches cell cycle mode from mitotic to meiotic division. GO:0099121 fungal sorus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099121 The process whose specific outcome is the progression of a fungal sorus over time, from its formation to the mature structure. A fungal sorus is a spore containing structure. GO:0110041 regulation of pharynx morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110041 Any process that modulates the frequency, rate or extent of pharynx morphogenesis, the process in which the anatomical structure of the pharynx is generated and organized. GO:0110042 negative regulation of pharynx morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110042 Any process that stops, prevents, or reduces the frequency, rate or extent of pharynx morphogenesis. GO:2000930 regulation of cellobiose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000930 regulation of cellobiose metabolism Any process that modulates the frequency, rate or extent of cellobiose metabolic process. GO:2000931 negative regulation of cellobiose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000931 negative regulation of cellobiose metabolism Any process that stops, prevents or reduces the frequency, rate or extent of cellobiose metabolic process. GO:2000932 positive regulation of cellobiose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000932 positive regulation of cellobiose metabolism Any process that activates or increases the frequency, rate or extent of cellobiose metabolic process. GO:0110040 pharynx morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110040 The process in which the anatomical structures of the pharynx are generated and organized. GO:2000933 regulation of cellotriose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000933 regulation of cellotriose metabolism Any process that modulates the frequency, rate or extent of cellotriose metabolic process. GO:2000934 negative regulation of cellotriose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000934 negative regulation of cellotriose metabolism Any process that stops, prevents or reduces the frequency, rate or extent of cellotriose metabolic process. GO:2000935 positive regulation of cellotriose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000935 positive regulation of cellotriose metabolism Any process that activates or increases the frequency, rate or extent of cellotriose metabolic process. GO:2000936 regulation of cellotriose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000936 regulation of cellotriose catabolism Any process that modulates the frequency, rate or extent of cellotriose catabolic process. CHEBI:16749 1-phosphatidyl-1D-myo-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16749 CHEBI:16746 1,2,3,5-tetrahydroxybenzene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16746 CHEBI:16747 4-methylene-L-glutamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16747 CHEBI:16744 pregna-4,9(11)-diene-3,20-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16744 GO:0075170 obsolete negative regulation of protein kinase-mediated signal transduction in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075170 negative regulation of symbiont protein kinase-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont protein kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075171 obsolete regulation of MAP kinase-mediated signal transduction in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075171 regulation of symbiont MAP kinase-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its MAP kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:16742 orotic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16742 GO:0075172 obsolete positive regulation of MAP kinase-mediated signal transduction in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075172 positive regulation of symbiont MAP kinase-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its MAP kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:16743 D-tagatose 1,6-bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16743 GO:0075173 obsolete negative regulation of MAP kinase-mediated signal transduction in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075173 negative regulation of symbiont MAP kinase-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont MAP kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:16740 trans-cyclohexa-3,5-diene-1,2-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16740 GO:0075174 obsolete regulation of cAMP-mediated signaling in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075174 regulation of cAMP-mediated signalling in response to host|regulation of symbiont cAMP-mediated signal transduction in response to host|regulation of cAMP-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its cAMP-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:16741 4-(beta-D-glucosyloxy)benzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16741 GO:0075175 obsolete positive regulation of cAMP-mediated signaling in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075175 positive regulation of cAMP-mediated signalling in response to host|positive regulation of cAMP-mediated signal transduction in response to host|positive regulation of symbiont cAMP-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its cAMP-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075176 obsolete negative regulation of cAMP-mediated signaling in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075176 negative regulation of symbiont cAMP-mediated signal transduction in response to host|negative regulation of cAMP-mediated signal transduction in response to host|negative regulation of cAMP-mediated signalling in response to host OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its cAMP-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. UBERON:0008397 tracheobronchial epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008397 bronchotracheal epithelium Epithelium pertaining to the trachea and bronchi. GO:0075177 obsolete regulation of calcium or calmodulin-mediated signal transduction in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075177 modulation of symbiont Ca++ or calmodulin-mediated signal transduction in response to host|modulation of symbiont calcium or calmodulin-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its calcium or calmodulin-mediated signal transduction as a result of detecting host molecules in, on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075178 obsolete positive regulation of calcium or calmodulin-mediated signal transduction in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075178 positive regulation of symbiont calcium or calmodulin-mediated signal transduction in response to host|positive regulation of symbiont Ca++ or calmodulin-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its calcium or calmodulin-mediated signal transduction as a result of detecting host molecules in, on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0099128 mitochondrial iron-sulfur cluster assembly complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0099128 A protein complex consisting of frataxin, cysteine desulfurase, an accessory protein and a Fe-S scaffold protein. In human these genes correspond to FXN, NFS1, ISD11 and ISCU respectively. This complex assembles Fe-S clusters onto the scaffolding protein using the substrates ferrous iron, electrons, and sulfur from l-cysteine. GO:0075179 obsolete negative regulation of calcium or calmodulin-mediated signal transduction in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075179 negative regulation of symbiont calcium or calmodulin-mediated signal transduction in response to host|negative regulation of symbiont Ca++ or calmodulin-mediated signal transduction in response to host OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont calcium or calmodulin-mediated signal transduction as a result of detecting host molecules in, on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0099129 cochlear outer hair cell electromotile response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099129 A rapid, force generating length change of an outer hair cell in response to electical stimulation. This occurs naturally as during hearing where it serves a source of mechanical amplification. GO:0099179 regulation of synaptic membrane adhesion biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099179 regulation of synapse adhesion between pre- and post-synapse Any process that modulates the frequency, rate or extent of adhesion between pre- and post-synaptic membranes. GO:0099177 regulation of trans-synaptic signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099177 Any process that modulates the frequency, rate or extent of trans-synaptic signaling. GO:0099178 regulation of retrograde trans-synaptic signaling by endocanabinoid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099178 regulation of endocannabinoid-mediated retrograde trans-synaptic signaling Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by an endocannabinoid. GO:0099175 regulation of postsynapse organization biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099175 regulation of postsynapse organisation|regulation of postsynapse structure|regulation of postsynapse organization and biogenesis Any process that modulates the physical form of a postsynapse. GO:0099176 regulation of retrograde trans-synaptic signaling by trans-synaptic protein complex biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099176 regulation of trans-synaptic complex mediated retrograde trans-synaptic signaling Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by a trans-synaptic complex. GO:0099173 postsynapse organization biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099173 postsynapse organization and biogenesis|postsynapse morphogenesis|postsynapse organisation|postsynapse development A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a postsynapse. GO:0099174 regulation of presynapse organization biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099174 regulation of presynapse organisation|regulation of presynapse structure|regulation of presynapse organization and biogenesis Any process that modulates the physical form of a presynapse. GO:0099171 presynaptic modulation of chemical synaptic transmission biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099171 Any process, acting in the presynapse that results in modulation of chemical synaptic transmission. GO:0099172 presynapse organization biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099172 presynapse development|presynapse organisation|presynapse organization and biogenesis|presynapse morphogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a presynapse. GO:0099170 postsynaptic modulation of chemical synaptic transmission biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099170 Any process, acting in the postsynapse that results in modulation of chemical synaptic transmission. GO:0099188 postsynaptic cytoskeleton organization biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099188 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising cytoskeletal filaments and their associated proteins in the postsynaptic cytoskeleton. GO:0099189 postsynaptic spectrin-associated cytoskeleton biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099189 The portion of the spectrin-associated cytoskeleton contained within the postsynapse. GO:0099186 structural constituent of postsynapse biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099186 The action of a molecule that contributes to the structural integrity of a postsynapse. GO:0099187 presynaptic cytoskeleton organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099187 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures and their associated proteins in the presynaptic cytoskeleton. GO:0099184 structural constituent of postsynaptic intermediate filament cytoskeleton biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099184 The action of a molecule that contributes to the structural integrity of a postsynaptic intermediate filament cytoskeleton. GO:0099185 postsynaptic intermediate filament cytoskeleton organization biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099185 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprised of intermediate filament and their associated proteins in the postsynaptic cytoskeleton. GO:0099182 presynaptic intermediate filament cytoskeleton biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099182 The intermediate filament cytoskeleton that is part of a presynapse. GO:0099183 trans-synaptic signaling by BDNF, modulating synaptic transmission biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099183 Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of brain derived neurotrophic factor (BDNF), that modulates the synaptic transmission properties of the synapse. GO:0099180 zinc ion import into synaptic vesicle biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099180 Zn2+ import into synaptic vesicle|zinc import into synaptic vesicle The directed movement of Zn2+ ions from the cytoplasm into the lumen of a cytoplasmic vesicle. GO:0099181 structural constituent of presynapse biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099181 The action of a molecule that contributes to the structural integrity of a presynapse. GO:0075190 negative regulation of hyphopodium formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075190 negative regulation of hyphopodium formation on or near host Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont hyphopodium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075191 obsolete autophagy of host cells on or near symbiont surface biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075191 OBSOLETE. The process in which the host cells digest parts of their own cytoplasm, occurring when the host is on or near its symbiont surface. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075192 haustorium mother cell formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075192 haustorium mother cell formation on or near host The process in which a symbiont cell is formed, separated from the tip of an infection hypha by a septum. The haustorium mother cell usually contains 2-4 fungal nuclei, and its function is to attach and penetrate the host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075193 regulation of haustorium mother cell formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075193 regulation of haustorium mother cell formation on or near host Any process that modulates the frequency, rate or extent of symbiont haustorium mother cell formation. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075194 positive regulation of haustorium mother cell formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075194 positive regulation of haustorium mother cell formation on or near host Any process that activates or increases the frequency, rate or extent of symbiont haustorium mother cell formation. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075195 negative regulation of haustorium mother cell formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075195 negative regulation of haustorium mother cell formation on or near host Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont haustorium mother cell formation. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075196 adhesion of symbiont haustorium mother cell to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075196 adhesion of symbiont haustorium mother cell to host during symbiotic interaction The attachment of a haustorium mother cell of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075197 haustorium neck formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075197 formation of symbiont haustorium neck for entry into host|symbiont haustorium neck formation for entry into host The assembly by the symbiont of a neck-like structure for the purpose of penetration into its host organism. The neck-like structure connects haustorium mother cell and haustorium. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075198 modulation of symbiont haustorium neck formation for entry into host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075198 Any process that modulates the frequency, rate or extent of symbiont haustorium neck formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075199 positive regulation of symbiont haustorium neck formation for entry into host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075199 Any process that activates, maintains or increases the frequency, rate or extent of symbiont haustorium neck formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0099159 regulation of modification of postsynaptic structure biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099159 regulation of postsynapse remodelling Any process that modulates the frequency, rate or extent of modification of postsynaptic structure. GO:0099157 trans-synaptic signalling via exosome biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099157 exosome mediated transynaptic signalling Transynaptic signaling in which the ligand is carried across the synapse by an exosome. GO:0099158 regulation of recycling endosome localization within postsynapse biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099158 Any process that modulates the frequency, rate or extent of transport or maintenance of location of a postsynaptic recycling endosome within the postsynapse. GO:0099155 synaptic transmission, noradrenergic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099155 noradrenergic synaptic transmission The vesicular release of noradrenaline (norepinephrine) a presynapse, across a chemical synapse, the subsequent activation of noradrenaline receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. GO:0099156 cell-cell signaling via exosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099156 exosome mediated Cell-cell signaling in which the ligand is carried between cells by an exosome. GO:0099153 synaptic transmission, serotonergic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099153 serotonergic synaptic transmission The vesicular release of serotonin from a presynapse, across a chemical synapse, the subsequent activation of serotonin receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. GO:0099154 serotonergic synapse biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099154 A synapse that uses serotonin as a neurotransmitter. GO:0099151 regulation of postsynaptic density assembly biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099151 Any process that modulates the frequency, rate or extent of postsynaptic density assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynaptic density. GO:0099152 regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099152 Any process that modulates the frequency, rate or extent of the directed movement of neurotransmitter receptor from the postsynaptic endosome to the postsynaptic membrane in transport vesicles. CHEBI:145182 1-O-(1Z-octadecenyl)-2-acyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_145182 GO:0099150 regulation of postsynaptic specialization assembly biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099150 Any process that modulates the frequency, rate or extent of postsynaptic specialization assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynaptic specialization. CHEBI:16719 (R)-pantolactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16719 CHEBI:145187 1-O-octadecyl-2-acyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_145187 CHEBI:16717 (Z)-but-2-ene-1,2,3-tricarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16717 CHEBI:16718 (S)-reticuline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16718 CHEBI:65737 demethoxycurcumin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65737 CHEBI:16715 1,5-anhydro-D-fructose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16715 CHEBI:16716 benzene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16716 CHEBI:16713 2-aminopteridine-4,7-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16713 CHEBI:16714 codeine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16714 CHEBI:16711 4-hydroxybut-2-ynal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16711 CHEBI:16712 (S)-3-sulfolactic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16712 CHEBI:16710 D-ribulose 1,5-bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16710 CHEBI:145178 1-O-octadecyl-2-oleoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_145178 GO:0110005 positive regulation of tRNA C5-cytosine methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110005 Any process that activates or increases the frequency, rate or extent of tRNA C5-cytosine methylation. GO:0099168 extrinsic component of postsynaptic specialization membrane of symmetric synapse biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099168 The component of the postsynaptic specialization membrane of a symmetric synapse consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:0110003 regulation of tRNA C5-cytosine methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110003 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tRNA C5-cytosine methylation. GO:0110004 positive regulation of tRNA methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110004 Any process that activates or increases the frequency, rate or extent of tRNA methylation. GO:0099169 anchored component of postsynaptic specialization membrane of symmetric synapse biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099169 The component of the postsynaptic specialization membrane of a symmetric synapse consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. GO:0099166 intrinsic component of postsynaptic specialization membrane of symmetric synapse biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099166 intrinsic to postsynaptic specialization membrane of symmetric synapse The component of the postsynaptic specialization membrane of a symmetric synapse consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0110001 toxin-antitoxin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0110001 IntAct:EBI-13949715|IntAct:EBI-13949218|IntAct:EBI-13949851|IntAct:EBI-13949147|IntAct:EBI-10919614|IntAct:EBI-13949593 A bacterial protein complex that neutralises its own toxin by complexing the toxin with the antitoxin. The antitoxin can be either a protein or an RNA. The neutralising toxin-antitoxin complex also acts as a transcriptional repressor of the toxin-antitoxin operon. GO:0099167 integral component of postsynaptic specialization membrane of symmetric synapse biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099167 The component of the postsynaptic specialization membrane of a symmetric synapse consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0110002 regulation of tRNA methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110002 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tRNA methylation. GO:0099164 postsynaptic specialization membrane of symmetric synapse biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099164 The membrane component of the postsynaptic specialization of a symmetic synapse. This is the region of the postsynaptic membrane in which the population of neurotransmitter receptors involved in synaptic transmission are concentrated. GO:0099165 postsynaptic specialization of symmetric synapse, intracellular component biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099165 A network of proteins adjacent to the postsynaptic membrane of a symmetric synapse. Its major components include that spatially and functionally organize neurotransmitter receptors in the adjacent membrane, such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components. This structure is not as thick or electron dense as the postsynaptic density found in asymmetric synapses. GO:0099162 regulation of neurotransmitter loading into synaptic vesicle biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099162 regulation of synaptic vesicle neurotransmitter loading|regulation of neurotransmitter uptake into synaptic vesicle Any process that modulates the frequency, rate or extent of neurotransmitter loading into synaptic vesicles. GO:0099163 synaptic signaling by nitric oxide biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099163 Cell-cell signaling to or from a synapse, mediated by nitric oxide. GO:0099160 postsynaptic intermediate filament cytoskeleton biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099160 The intermediate filament cytoskeleton that is part of a postsynapse. GO:0099161 regulation of presynaptic dense core granule exocytosis biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099161 regulation of presynaptic dense core vesicle exocytosis Any process that modulates the frequency, rate or extent of presynaptic dense core granule exocytosis. CHEBI:16708 adenine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16708 CHEBI:16709 pyridoxine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16709 CHEBI:16706 2-iodophenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16706 CHEBI:16704 uridine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16704 CHEBI:16705 6-aminopenicillanic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16705 CHEBI:16702 N-sulfo-D-glucosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16702 CHEBI:16700 indican biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16700 CHEBI:16701 nucleoside 5'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16701 GO:0110009 formin-nucleated actin cable organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110009 A process that results in the assembly, arrangement of constituent parts, or disassembly of a formin-nucleated actin cable. GO:0110008 ncRNA deadenylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110008 Shortening of the poly(A) tail of a nuclear-transcribed ncRNA. GO:0051115 obsolete enzyme active site formation via 1'-(phospho-5'-uridine)-L-histidine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051115 RESID:AA0372 OBSOLETE. The transient uridylylation of peptidyl-histidine to form 1'-(phospho-5'-uridine)-L-histidine (otherwise known as tau-UMP-histidine, tele-UMP-histidine). GO:0051116 cobaltochelatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051116 KEGG_REACTION:R05227|MetaCyc:R342-RXN|EC:6.6.1.2|RHEA:15341 hydrogenobyrinic-acid-a,c-diamide:cobalt cobalt-ligase (ADP-forming)|hydrogenobyrinic acid a,c-diamide cobaltochelatase activity|CobN-CobST|CobNST Catalysis of the reaction: ATP + Co(2+) + H(2)O + hydrogenobyrinate a,c-diamide = ADP + cob(II)yrinate a,c diamide + 4 H(+) + phosphate. GO:0051113 obsolete enzyme active site formation via 1'-(phospho-5'-adenosine)-L-histidine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051113 RESID:AA0371 OBSOLETE. The transient adenylylation of peptidyl-histidine to form 1'-(phospho-5'-adenosine)-L-histidine (otherwise known as tau-AMP-histidine, tele-AMP-histidine). GO:0051114 peptidyl-histidine uridylylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051114 RESID:AA0372 The uridylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-uridine)-L-histidine (otherwise known as tau-UMP-histidine, tele-UMP-histidine) or peptidyl-3'-(phospho-5'-uridine)-L-histidine (otherwise known as pi-UMP-histidine, pros-UMP-histidine). GO:0051119 sugar transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051119 Reactome:R-HSA-428779|Reactome:R-HSA-8876319|Reactome:R-HSA-8875902 sugar/polyol channel activity Enables the transfer of a sugar from one side of a membrane to the other. A sugar is any member of a class of sweet, water-soluble, crystallizable carbohydrates, which are the monosaccharides and smaller oligosaccharides. CHEBI:26147 piperidine alkaloid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26147 CHEBI:26148 piperidinemonocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26148 GO:0110098 positive regulation of calcium import into the mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110098 Any process that activates or increases the frequency, rate or extent of calcium import into the mitochondrion. GO:0051117 ATPase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051117 Interacting selectively and non-covalently with an ATPase, any enzyme that catalyzes the hydrolysis of ATP. GO:0051118 glucan endo-1,3-alpha-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051118 EC:3.2.1.59|MetaCyc:3.2.1.59-RXN cariogenanase activity|endo-1,3-alpha-glucanase activity|mutanase activity|cariogenase activity|endo-(1->3)-alpha-glucanase activity|1,3(1,3;1,4)-alpha-D-glucan 3-glucanohydrolase activity|endo-1,3-alpha-D-glucanase activity Catalysis of the endohydrolysis of (1->3)-alpha-D-glucosidic linkages in isolichenin, pseudonigeran and nigeran. GO:0110099 negative regulation of calcium import into the mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110099 Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import into the mitochondrion. GO:2000984 negative regulation of ATP citrate synthase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000984 negative regulation of acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP-phosphorylating)|negative regulation of acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating]|negative regulation of ATP-citric lyase activity|negative regulation of citric cleavage enzyme activity|negative regulation of adenosine triphosphate citrate lyase activity|negative regulation of ATP-citrate (pro-S)-lyase activity|negative regulation of ATP:citrate oxaloacetate-lyase ((pro-S)-CH(2)COO(-)->acetyl-CoA) (ATP- dephosphorylating) activity|negative regulation of ATP-citrate (pro-S-)-lyase activity|negative regulation of ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-rightacetyl-CoA] (ATP-dephosphorylating)|negative regulation of ATP citrate (pro-S)-lyase activity|negative regulation of acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP- phosphorylating) activity|negative regulation of citrate-ATP lyase activity|negative regulation of citrate cleavage enzyme activity Any process that stops, prevents or reduces the frequency, rate or extent of ATP citrate synthase activity. GO:0110096 cellular response to aldehyde biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110096 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldehyde stimulus. GO:2000985 positive regulation of ATP citrate synthase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000985 positive regulation of citrate cleavage enzyme activity|positive regulation of ATP-citric lyase activity|positive regulation of citric cleavage enzyme activity|positive regulation of acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP-phosphorylating)|positive regulation of adenosine triphosphate citrate lyase activity|positive regulation of acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating]|positive regulation of ATP-citrate (pro-S)-lyase activity|positive regulation of ATP-citrate (pro-S-)-lyase activity|positive regulation of ATP:citrate oxaloacetate-lyase ((pro-S)-CH(2)COO(-)->acetyl-CoA) (ATP- dephosphorylating) activity|positive regulation of ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-rightacetyl-CoA] (ATP-dephosphorylating)|positive regulation of ATP citrate (pro-S)-lyase activity|positive regulation of acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP- phosphorylating) activity|positive regulation of citrate-ATP lyase activity Any process that activates or increases the frequency, rate or extent of ATP citrate synthase activity. CHEBI:26144 piperazines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26144 GO:0110097 regulation of calcium import into the mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110097 Any process that modulates the frequency, rate or extent of calcium import into the mitochondrion. GO:0110094 polyphosphate-mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110094 polyphosphate signaling Any process that mediates the transfer of information from one cell to another using polyphosphate as the signal. GO:0090718 adaptive immune effector response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090718 An adaptive immune response that involves one or more immune effector processes and takes place during the effector phase of the adaptive immune response. GO:2000986 negative regulation of behavioral fear response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000986 negative regulation of behavioural fear response Any process that stops, prevents or reduces the frequency, rate or extent of behavioral fear response. CHEBI:26145 piperideine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26145 GO:2000987 positive regulation of behavioral fear response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000987 positive regulation of behavioural fear response Any process that activates or increases the frequency, rate or extent of behavioral fear response. GO:0090719 adaptive immune effector response involving T cells and B lineage cells biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090719 An adaptive immune effector response involving T cells and B lineage cells. In the case of B lineage cells, the effector cells are the antibody secreting plasma cells whereas for T cells the effector cells may be helper T cells or cytotoxic T cells. GO:0110095 cellular detoxification of aldehyde biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110095 Any process carried out at the cellular level that reduces or removes the toxicity of an aldehyde. These may include transport of aldehydes away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance. GO:0110092 nucleus leading edge biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0110092 horsetail nucleus leading edge The area of a motile nucleus closest to the direction of movement. GO:2000988 regulation of hemicellulose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000988 regulation of hemicellulose catabolism Any process that modulates the frequency, rate or extent of hemicellulose catabolic process. GO:0110093 nucleus lagging edge biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0110093 The area of a motile nucleus furthest from the direction of movement. GO:2000989 negative regulation of hemicellulose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000989 negative regulation of hemicellulose catabolism Any process that stops, prevents or reduces the frequency, rate or extent of hemicellulose catabolic process. GO:1905530 negative regulation of uracil import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905530 Any process that stops, prevents or reduces the frequency, rate or extent of uracil import across plasma membrane. GO:0110090 positive regulation of hippocampal neuron apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110090 Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process in hippocampal neurons. GO:0110091 negative regulation of hippocampal neuron apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110091 Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in hippocampal neurons. GO:1905531 positive regulation of uracil import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905531 Any process that activates or increases the frequency, rate or extent of uracil import across plasma membrane. GO:1905521 regulation of macrophage migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905521 Any process that modulates the frequency, rate or extent of macrophage migration. GO:0090723 obsolete growth cone part biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090723 OBSOLETE. Any constituent part of a growth cone, the migrating motile tip of a growing nerve cell axon or dendrite. GO:0090724 central region of growth cone biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090724 The center of the migrating motile tip of a growing nerve cell axon or dendrite. GO:1905522 negative regulation of macrophage migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905522 down-regulation of macrophage migration|downregulation of macrophage migration|down regulation of macrophage migration|inhibition of macrophage migration Any process that stops, prevents or reduces the frequency, rate or extent of macrophage migration. GO:0090721 primary adaptive immune response involving T cells and B cells biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090721 An adaptive immune response mediated by naive T or B cells against an antigen not previously encountered by immune system. GO:1905523 positive regulation of macrophage migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905523 up regulation of macrophage migration|upregulation of macrophage migration|up-regulation of macrophage migration|activation of macrophage migration Any process that activates or increases the frequency, rate or extent of macrophage migration. GO:0090722 receptor-receptor interaction biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090722 hetero-receptor complex formation The aggregation, arrangement and bonding together of two or more different receptor complexes that individually undergo combination with a hormone, neurotransmitter, drug or intracellular messenger to form a higher level receptor complex. The formation of the higher level complex initiates a change in cell function. GO:1905524 negative regulation of protein autoubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905524 negative regulation of protein self-ubiquitination|down-regulation of protein self-ubiquitination|negative regulation of protein auto-ubiquitination|down-regulation of protein auto-ubiquitination|downregulation of protein autoubiquitination|inhibition of protein self-ubiquitination|down regulation of protein self-ubiquitinylation|inhibition of protein auto-ubiquitination|down regulation of protein autoubiquitination|down regulation of protein auto-ubiquitinylation|downregulation of protein self-ubiquitinylation|inhibition of protein autoubiquitination|downregulation of protein auto-ubiquitinylation|down-regulation of protein autoubiquitinylation|negative regulation of protein autoubiquitinylation|down regulation of protein self-ubiquitination|down-regulation of protein self-ubiquitinylation|negative regulation of protein self-ubiquitinylation|negative regulation of protein auto-ubiquitinylation|down-regulation of protein auto-ubiquitinylation|down regulation of protein auto-ubiquitination|downregulation of protein self-ubiquitination|downregulation of protein autoubiquitinylation|inhibition of protein self-ubiquitinylation|downregulation of protein auto-ubiquitination|down-regulation of protein autoubiquitination|inhibition of protein auto-ubiquitinylation|down regulation of protein autoubiquitinylation|inhibition of protein autoubiquitinylation Any process that stops, prevents or reduces the frequency, rate or extent of protein autoubiquitination. GO:1905525 obsolete regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905525 regulation of ferrichrome anabolism by inhibition of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome anabolism by negative regulation of transcription from Pol II promoter in response to iron|regulation of ferrichrome biosynthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process by downregulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process by down-regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from Pol II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome anabolism by down regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome formation by downregulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide formation by inhibition of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome synthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome synthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from Pol II promoter in response to iron|regulation of ferrichrome formation by down regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome anabolism by downregulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide modification by inhibition of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process by negative regulation of transcription from Pol II promoter in response to iron|regulation of ferrichrome biosynthesis by negative regulation of transcription from Pol II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide modification by down regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process by inhibition of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome anabolism by negative regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome anabolism by down-regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide formation by downregulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process by down regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome synthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome synthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome formation by inhibition of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide formation by down regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome formation by negative regulation of transcription from Pol II promoter in response to iron|regulation of ferrichrome formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome synthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome synthesis by negative regulation of transcription from Pol II promoter in response to iron|regulation of ferrichrome formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide modification by downregulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide modification by down-regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from RNA polymerase II promoter in response to iron OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter in response to iron that results in regulation of ferrichrome biosynthetic process. GO:0090727 positive regulation of brood size biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090727 Any process that increases brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time. GO:2000980 regulation of inner ear receptor cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000980 regulation of inner ear hair cell differentiation Any process that modulates the frequency, rate or extent of inner ear receptor cell differentiation. GO:0090728 negative regulation of brood size biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090728 Any process that decreases brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time. GO:2000981 negative regulation of inner ear receptor cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000981 negative regulation of inner ear hair cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of inner ear receptor cell differentiation. GO:1905526 regulation of Golgi lumen acidification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905526 Any process that modulates the frequency, rate or extent of Golgi lumen acidification. GO:2000982 positive regulation of inner ear receptor cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000982 positive regulation of inner ear hair cell differentiation Any process that activates or increases the frequency, rate or extent of inner ear receptor cell differentiation. GO:0090725 peripheral region of growth cone biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090725 The non-central region or periphery of the migrating motile tip of a growing nerve cell axon or dendrite. GO:1905527 negative regulation of Golgi lumen acidification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905527 down regulation of Golgi lumen acidification|downregulation of Golgi lumen acidification|down-regulation of Golgi lumen acidification|inhibition of Golgi lumen acidification Any process that stops, prevents or reduces the frequency, rate or extent of Golgi lumen acidification. GO:2000983 regulation of ATP citrate synthase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000983 regulation of ATP citrate (pro-S)-lyase activity|regulation of acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP- phosphorylating) activity|regulation of citrate-ATP lyase activity|regulation of citrate cleavage enzyme activity|regulation of ATP-citrate (pro-S-)-lyase activity|regulation of ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-rightacetyl-CoA] (ATP-dephosphorylating)|regulation of acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP-phosphorylating)|regulation of acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating]|regulation of ATP-citrate (pro-S)-lyase activity|regulation of ATP:citrate oxaloacetate-lyase ((pro-S)-CH(2)COO(-)->acetyl-CoA) (ATP- dephosphorylating) activity|regulation of ATP-citric lyase activity|regulation of citric cleavage enzyme activity|regulation of adenosine triphosphate citrate lyase activity Any process that modulates the frequency, rate or extent of ATP citrate synthase activity. GO:0090726 cortical dynamic polarity patch biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090726 dynamic polarity patch at the cell cortex A region of the cell cortex that contains a higher concentration of growth polarity factors than the surrounding cortex and that changes position over time. An example is found in fission yeast cells during early mating, in which the GTPase Cdc42 dynamically to discrete zones within the cortex prior to shmoo formation. GO:1905528 positive regulation of Golgi lumen acidification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905528 upregulation of Golgi lumen acidification|up regulation of Golgi lumen acidification|activation of Golgi lumen acidification|up-regulation of Golgi lumen acidification Any process that activates or increases the frequency, rate or extent of Golgi lumen acidification. GO:1905529 regulation of uracil import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905529 Any process that modulates the frequency, rate or extent of uracil import across plasma membrane. UBERON:0008342 intestinal villus of duodenum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008342 An intestinal villus in the duodenum. GO:0051111 peptidyl-histidine adenylylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051111 RESID:AA0371 The adenylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-adenosine)-L-histidine (otherwise known as tau-AMP-histidine, tele-AMP-histidine) or peptidyl-3'-(phospho-5'-adenosine)-L-histidine (otherwise known as pi-AMP-histidine, pros-AMP-histidine). GO:0051112 peptidyl-histidine adenylylation, to form peptidyl-1'-(phospho-5'-adenosine)-L-histidine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051112 RESID:AA0371 The adenylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-adenosine)-L-histidine (otherwise known as tau-AMP-histidine, tele-AMP-histidine). GO:0090720 primary adaptive immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090720 An adaptive immune response against an antigen not previously encountered by immune system. GO:0051110 peptidyl-histidine uridylylation, to form peptidyl-1'-(phospho-5'-uridine)-L-histidine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051110 RESID:AA0372 The uridylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-uridine)-L-histidine (otherwise known as tau-UMP-histidine, tele-UMP-histidine). UBERON:0008346 duodenal epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008346 epithelium of duodenum An epithelium that is part of a duodenum. GO:0051126 negative regulation of actin nucleation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051126 downregulation of actin nucleation|down regulation of actin nucleation|inhibition of actin nucleation|down-regulation of actin nucleation Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament. GO:0051127 positive regulation of actin nucleation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051127 up regulation of actin nucleation|upregulation of actin nucleation|stimulation of actin nucleation|up-regulation of actin nucleation|activation of actin nucleation Any process that activates or increases the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament. GO:0051124 synaptic growth at neuromuscular junction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051124 cholinergic synaptogenesis The growth of a synapse at a neuromuscular junction, the site of apposition of a motor end plate and the subneural cleft of the skeletal muscle fiber that it innervates. GO:0051125 regulation of actin nucleation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051125 Any process that modulates the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament. GO:0051128 regulation of cellular component organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organisation|regulation of cell organisation|regulation of cell organization|regulation of cellular component organization and biogenesis Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. GO:0051129 negative regulation of cellular component organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051129 down regulation of cell organization|downregulation of cell organization|down-regulation of cell organization|negative regulation of cellular component organization and biogenesis|negative regulation of cell organisation|inhibition of cell organization Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. GO:2000995 negative regulation of mannan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000995 negative regulation of mannan catabolism|negative regulation of mannan degradation|negative regulation of mannan breakdown Any process that stops, prevents or reduces the frequency, rate or extent of mannan catabolic process. GO:2000996 positive regulation of mannan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000996 positive regulation of mannan degradation|positive regulation of mannan breakdown|positive regulation of mannan catabolism Any process that activates or increases the frequency, rate or extent of mannan catabolic process. CHEBI:26155 plant growth regulator biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26155 GO:0090729 toxin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090729 Wikipedia:Toxin toxin receptor binding Interacting selectively with one or more biological molecules in another (target) organism, initiating pathogenesis (leading to an abnormal, generally detrimental state) in the target organism. The activity should refer to an evolved function of the active gene product, i.e. one that was selected for. Examples include the activity of botulinum toxin, and snake venom. GO:2000997 regulation of cellulose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000997 regulation of cellulose degradation|regulation of cellulose catabolism|regulation of cellulose breakdown Any process that modulates the frequency, rate or extent of cellulose catabolic process. GO:2000998 negative regulation of cellulose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000998 negative regulation of cellulose degradation|negative regulation of cellulose breakdown|negative regulation of cellulose catabolism Any process that stops, prevents or reduces the frequency, rate or extent of cellulose catabolic process. GO:2000999 positive regulation of cellulose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000999 positive regulation of cellulose degradation|positive regulation of cellulose breakdown|positive regulation of cellulose catabolism Any process that activates or increases the frequency, rate or extent of cellulose catabolic process. GO:1905540 interleukin-7 receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1905540 IL-7-receptor complex|IL7-receptor complex|IL-7 receptor complex|IL7 receptor complex A protein complex that binds interleukin-7 (IL-7) and that consists of, at a minimum, an interleukin, an alpha and a gamma chain as well as optional additional kinase subunits. The alpha chain binds IL-7 with high affinity and subsequently binds the cytokine receptor common gamma chain that forms part of multiple interleukin receptors. CHEBI:26151 piperidines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26151 GO:1905541 regulation of L-arginine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905541 regulation of L-arginine import into cell Any process that modulates the frequency, rate or extent of L-arginine import across plasma membrane. GO:1905542 negative regulation of L-arginine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905542 inhibition of L-arginine import into cell|negative regulation of L-arginine import into cell|down regulation of L-arginine import into cell|downregulation of L-arginine import into cell Any process that stops, prevents or reduces the frequency, rate or extent of L-arginine import across plasma membrane. CHEBI:26153 p-menthadien-3-one biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26153 GO:0090734 site of DNA damage biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090734 Wikipedia:DNA_repair A region of a chromosome at which DNA damage has occurred. DNA damage signaling and repair proteins accumulate at the lesion to respond to the damage and repair the DNA to form a continuous DNA helix. GO:1905532 regulation of leucine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905532 regulation of leucine import into cell|regulation of L-leucine import into cell Any process that modulates the frequency, rate or extent of leucine import across plasma membrane. GO:1905533 negative regulation of leucine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905533 negative regulation of L-leucine import into cell|down-regulation of L-leucine import into cell|down-regulation of leucine import into cell|downregulation of L-leucine import into cell|down regulation of L-leucine import into cell|downregulation of leucine import into cell|down regulation of leucine import into cell|inhibition of L-leucine import into cell|inhibition of leucine import into cell|negative regulation of leucine import into cell Any process that stops, prevents or reduces the frequency, rate or extent of leucine import across plasma membrane. GO:0090735 DNA repair complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090735 The aggregation, arrangement and bonding together of a set of components to form a DNA repair complex. GO:1905534 positive regulation of leucine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905534 up-regulation of L-leucine import into cell|positive regulation of leucine import into cell|activation of L-leucine import into cell|activation of leucine import into cell|up-regulation of leucine import into cell|positive regulation of L-leucine import into cell|up regulation of L-leucine import into cell|up regulation of leucine import into cell|upregulation of L-leucine import into cell|upregulation of leucine import into cell Any process that activates or increases the frequency, rate or extent of leucine import across plasma membrane. GO:0090732 cofilin-actin rod biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090732 A cellular structure consisting of parallel, hexagonally arranged actin tubules, comprising filamentous actin and disulfide cross-linked cofilin multimers. GO:1905535 regulation of eukaryotic translation initiation factor 4F complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905535 regulation of eIF-4F assembly|regulation of eIF4F assembly Any process that modulates the frequency, rate or extent of eukaryotic translation initiation factor 4F complex assembly. GO:2000990 positive regulation of hemicellulose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000990 positive regulation of hemicellulose catabolism Any process that activates or increases the frequency, rate or extent of hemicellulose catabolic process. GO:0090733 tenascin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090733 IntAct:EBI-13640819|IntAct:EBI-11789587 Tenascin-X|Tenascin-W|Tenascin-R|Tenascin-N|Tenascin-C A extracellular matrix complex involved in cell adhesion and cell migration. Typically homotrimeric or homohexameric. In mammals, four complexes exist: Tenascin-C, Tenascin-N (also known as Tenascin-W), Tenascin-X and Tenascin-R. GO:2000991 regulation of galactomannan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000991 Any process that modulates the frequency, rate or extent of galactomannan catabolic process. GO:1905536 negative regulation of eukaryotic translation initiation factor 4F complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905536 down regulation of eIF-4F assembly|downregulation of eIF-4F assembly|down-regulation of eukaryotic translation initiation factor 4F complex assembly|negative regulation of eIF4F assembly|down-regulation of eIF4F assembly|down-regulation of eIF-4F assembly|negative regulation of eIF-4F assembly|downregulation of eukaryotic translation initiation factor 4F complex assembly|downregulation of eIF4F assembly|inhibition of eIF-4F assembly|down regulation of eukaryotic translation initiation factor 4F complex assembly|inhibition of eukaryotic translation initiation factor 4F complex assembly|down regulation of eIF4F assembly|inhibition of eIF4F assembly Any process that stops, prevents or reduces the frequency, rate or extent of eukaryotic translation initiation factor 4F complex assembly. GO:1905537 positive regulation of eukaryotic translation initiation factor 4F complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905537 upregulation of eIF-4F assembly|up-regulation of eukaryotic translation initiation factor 4F complex assembly|activation of eukaryotic translation initiation factor 4F complex assembly|up-regulation of eIF4F assembly|activation of eIF4F assembly|up regulation of eIF-4F assembly|positive regulation of eIF-4F assembly|activation of eIF-4F assembly|positive regulation of eIF4F assembly|up regulation of eukaryotic translation initiation factor 4F complex assembly|up regulation of eIF4F assembly|up-regulation of eIF-4F assembly|upregulation of eukaryotic translation initiation factor 4F complex assembly|upregulation of eIF4F assembly Any process that activates or increases the frequency, rate or extent of eukaryotic translation initiation factor 4F complex assembly. GO:2000992 negative regulation of galactomannan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000992 Any process that stops, prevents or reduces the frequency, rate or extent of galactomannan catabolic process. GO:2000993 positive regulation of galactomannan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000993 Any process that activates or increases the frequency, rate or extent of galactomannan catabolic process. GO:0090736 MATH domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090736 Interacting selectively and non-covalently with a meprin and TRAF homology (MATH) domain. GO:1905538 polysome binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1905538 polyribosome binding Interacting selectively and non-covalently with a polysome. GO:0090737 telomere maintenance via telomere trimming biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090737 A process that contributes to the maintenance of proper telomeric length and structure via the activation of telomere shortening pathways that compensate telomerase-dependent excessive telomere elongation. Telomere attrition is mediated by a mechanism which involves the generation of single-stranded C-rich telomeric DNA, and the formation and removal of double-stranded telomeric circular DNA (T-circles). Telomere trimming is an independent pathway to recombination-mediated telomere elongation and the well-documented gradual telomere attrition that accompanies cellular replication. GO:1905539 regulation of postsynapse to nucleus signaling pathway biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_1905539 regulation of postsynaptic signaling to nucleus Any process that modulates the frequency, rate or extent of postsynapse to nucleus signaling pathway. GO:2000994 regulation of mannan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000994 regulation of mannan catabolism|regulation of mannan degradation|regulation of mannan breakdown Any process that modulates the frequency, rate or extent of mannan catabolic process. UBERON:0008331 clitoral smooth muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008331 clitoris smooth muscle A smooth muscle tissue that is part of a clitoris. GO:0090730 Las1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090730 Las1-Grc3-Rat1-Rai1 A four subunit complex, that comprises all the necessary RNA processing enzymes (endonuclease, polynucleotide kinase, and exonuclease) to mediate 'cistronic rRNA transcript ITS2 (internal transcribed spacer) cleavage' (GO:0000448). GO:0051122 hepoxilin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051122 hepoxilin anabolism|hepoxilin synthesis|hepoxilin formation|hepoxilin biosynthesis The chemical reactions and pathways resulting in the formation of hepoxilins, a class of bioactive icosanoids with roles in the regulation of cell physiology. GO:0090731 cellular response to very-low-density lipoprotein particle stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090731 cellular response to VLDL particle stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very-low-density lipoprotein particle stimulus. GO:0051123 RNA polymerase II preinitiation complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051123 RNA polymerase II transcriptional preinitiation complex formation|RNA polymerase II transcriptional preinitiation complex assembly|RNA polymerase II transcription PIC biosynthesis|RNA polymerase II transcription PIC formation The aggregation, arrangement and bonding together of proteins on an RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase. GO:0051120 hepoxilin A3 synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051120 Reactome:R-HSA-8942208|Reactome:R-HSA-2161794 Catalysis of the reaction: 12S-5Z,8Z,10E,14Z-12-hydro(pero)xy-eicosa-5,8,10,14-tetraenoic acid = (5Z,9E,14Z)-(8,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate. 12S-5Z,8Z,10E,14Z-12-hydro(pero)xy-eicosa-5,8,10,14-tetraenoic acid is also known as 12S-HpETE, and (5Z,9E,14Z)-(8,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate as hepoxilin A3. GO:0051121 hepoxilin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051121 hepoxilin metabolism The chemical reactions and pathways involving hepoxilins, a class of bioactive icosanoids with roles in the regulation of cell physiology. GO:0051137 negative regulation of NK T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051137 negative regulation of NK T lymphocyte differentiation|negative regulation of natural killer T cell differentiation|inhibition of NK T cell differentiation|negative regulation of NKT cell differentiation|negative regulation of natural T cell differentiation|negative regulation of NK T-cell differentiation|down regulation of NK T cell differentiation|negative regulation of NT cell differentiation|downregulation of NK T cell differentiation|negative regulation of NK T-lymphocyte differentiation|negative regulation of NK T cell development|down-regulation of NK T cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell differentiation. GO:0075104 obsolete positive regulation by host of symbiont calcium or calmodulin-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075104 positive regulation by host of symbiont Ca++ or calmodulin-mediated signal transduction OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051138 positive regulation of NK T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051138 up-regulation of NK T cell differentiation|positive regulation of NKT cell differentiation|positive regulation of NK T-cell differentiation|upregulation of NK T cell differentiation|positive regulation of NT cell differentiation|positive regulation of NK T-lymphocyte differentiation|positive regulation of natural T cell differentiation|up regulation of NK T cell differentiation|positive regulation of NK T cell development|activation of NK T cell differentiation|stimulation of NK T cell differentiation|positive regulation of NK T lymphocyte differentiation|positive regulation of natural killer T cell differentiation Any process that activates or increases the frequency, rate or extent of natural killer T cell differentiation. GO:0075105 obsolete negative regulation by host of symbiont calcium or calmodulin-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075105 negative regulation by host of symbiont Ca++ or calmodulin-mediated signal transduction OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051135 positive regulation of NK T cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051135 upregulation of NK T cell activation|positive regulation of NK T-cell activation|positive regulation of NKT cell activation|stimulation of NK T cell activation|up-regulation of NK T cell activation|activation of NK T cell activation|positive regulation of natural killer T cell activation|positive regulation of NK T lymphocyte activation|up regulation of NK T cell activation|positive regulation of natural T cell activation|positive regulation of NK T-lymphocyte activation|positive regulation of NT cell activation Any process that activates or increases the frequency, rate or extent of natural killer T cell activation. GO:0075106 modulation by symbiont of host adenylate cyclase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075106 Modulation by symbiont of host ATP diphosphate-lyase (cyclizing) activity|Modulation by symbiont of host ATP pyrophosphate-lyase activity|Modulation by symbiont of host adenyl cyclase activity|Modulation by symbiont of host ATP diphosphate-lyase (cyclizing ; 3',5'-cyclic-AMP-forming) activity|Modulation by symbiont of host adenylylcyclase activity|Modulation by symbiont of host cAMP generating peptide activity|Modulation by symbiont of host 3',5'-cyclic AMP synthetase activity|Modulation by symbiont of host adenylyl cyclase activity Any process in which the symbiont modulates the frequency, rate or extent of the host adenylate cyclase activity, which involves catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051136 regulation of NK T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051136 regulation of NK T-cell differentiation|regulation of NT cell differentiation|regulation of NK T-lymphocyte differentiation|regulation of NK T cell development|regulation of NKT cell differentiation|regulation of NK T lymphocyte differentiation|regulation of natural killer T cell differentiation|regulation of natural T cell differentiation Any process that modulates the frequency, rate or extent of natural killer T cell differentiation. GO:0075107 positive regulation by symbiont of host adenylate cyclase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075107 positive regulation by symbiont of host adenylyl cyclase activity|positive regulation by symbiont of host adenylylcyclase activity|positive regulation by symbiont of host 3',5'-cyclic AMP synthetase activity|positive regulation by symbiont of host adenyl cyclase activity|positive regulation by symbiont of host ATP diphosphate-lyase (cyclizing ; 3',5'-cyclic-AMP-forming) activity Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of the host adenylate cyclase activity, which involves catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075108 negative regulation by symbiont of host adenylate cyclase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075108 Negative regulation by symbiont of host adenylyl cyclase activity|Negative regulation by symbiont of host adenylylcyclase activity|Negative regulation by symbiont of host cAMP generating peptide activity|Negative regulation by symbiont of host adenyl cyclase activity|Negative regulation by symbiont of host 3',5'-cyclic AMP synthetase activity|Negative regulation by symbiont of host ATP diphosphate-lyase (cyclizing) activity|Negative regulation by symbiont of host ATP pyrophosphate-lyase activity|Negative regulation by symbiont of host ATP diphosphate-lyase (cyclizing ; 3',5'-cyclic-AMP-forming) activity Any process in which the symbiont stops, prevents, or reduces the frequency, rate or extent of the host adenylate cyclase activity, which catalyze the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:26125 phytosterols biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26125 GO:0075109 modulation by symbiont of host receptor-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075109 Any process in which the symbiont modulates the frequency, rate or extent of receptor-mediated signal transduction in the host organism. The receptor is defined as a protein on the cell membrane or within the cytoplasm or cell nucleus that binds to a specific molecule (a ligand) such as a neurotransmitter or a hormone or other substance, and initiates the cellular response to the ligand. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051139 metal ion:proton antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051139 Reactome:R-HSA-435171 metal ion:hydrogen antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: metal ion(in) + H+(out) = metal ion(out) + H+(in). CHEBI:26127 phytylnaphthoquinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26127 CHEBI:26124 phytosteroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26124 GO:1905550 regulation of protein localization to endoplasmic reticulum biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905550 regulation of protein localization in ER|regulation of protein localization in endoplasmic reticulum|regulation of protein localisation in endoplasmic reticulum Any process that modulates the frequency, rate or extent of protein localization to endoplasmic reticulum. GO:1905551 negative regulation of protein localization to endoplasmic reticulum biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905551 inhibition of protein localisation in endoplasmic reticulum|downregulation of protein localization in ER|inhibition of protein localization to endoplasmic reticulum|down regulation of protein localization in ER|inhibition of protein localization in ER|down regulation of protein localization in endoplasmic reticulum|downregulation of protein localization in endoplasmic reticulum|down regulation of protein localisation in endoplasmic reticulum|down regulation of protein localization to endoplasmic reticulum|downregulation of protein localisation in endoplasmic reticulum|down-regulation of protein localization in endoplasmic reticulum|negative regulation of protein localization in endoplasmic reticulum|downregulation of protein localization to endoplasmic reticulum|down-regulation of protein localization in ER|negative regulation of protein localization in ER|inhibition of protein localization in endoplasmic reticulum|down-regulation of protein localisation in endoplasmic reticulum|negative regulation of protein localisation in endoplasmic reticulum|down-regulation of protein localization to endoplasmic reticulum Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to endoplasmic reticulum. GO:0089710 endocytic targeting sequence binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0089710 Interacting selectively and non-covalently with a endocytic signal sequence, a specific peptide sequence, of 4-6 amino acids with an essential tyrosine (Y), found on cytoplasmic tails of some cell surface membrane proteins, which directs internalization by clathrin-coated pits. GO:1905552 positive regulation of protein localization to endoplasmic reticulum biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905552 up-regulation of protein localisation in endoplasmic reticulum|upregulation of protein localization in endoplasmic reticulum|up-regulation of protein localization to endoplasmic reticulum|upregulation of protein localization in ER|upregulation of protein localisation in endoplasmic reticulum|up regulation of protein localization in endoplasmic reticulum|upregulation of protein localization to endoplasmic reticulum|positive regulation of protein localization in endoplasmic reticulum|activation of protein localization in endoplasmic reticulum|up-regulation of protein localization in ER|activation of protein localization in ER|up regulation of protein localisation in endoplasmic reticulum|activation of protein localisation in endoplasmic reticulum|positive regulation of protein localisation in endoplasmic reticulum|up regulation of protein localization to endoplasmic reticulum|activation of protein localization to endoplasmic reticulum|up-regulation of protein localization in endoplasmic reticulum|positive regulation of protein localization in ER|up regulation of protein localization in ER Any process that activates or increases the frequency, rate or extent of protein localization to endoplasmic reticulum. GO:1905553 regulation of blood vessel branching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905553 regulation of branching involved in blood vessel morphogenesis Any process that modulates the frequency, rate or extent of blood vessel branching. GO:0089711 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0089711 CHEBI:26120 phytofluene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_26120 GO:1905543 interleukin-15 receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1905543 interleukin-15-receptor complex|IL15-receptor complex|IL-15-receptor complex|IL15 receptor complex|IL-15 receptor complex A protein complex that binds interleukin-15 (IL-15) and that consists of, at a minimum, an interleukin, an alpha, beta and gamma chain as well as optional additional kinase subunits. The alpha chain is unique to binds IL-15 while it shares the beta chain with the IL-2 receptor and the cytokine receptor common gamma chain with multiple interleukin receptors. GO:0089712 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0089712 GO:0090701 specification of plant organ identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090701 The regionalization process in which the identity of a plant organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized. GO:0089713 Cbf1-Met4-Met28 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0089713 A heteromeric complex consisting of Cbf1 and basic leucine zipper (bZIP) containing transcriptional activators, Met4 and Met28, that forms over the sequence TCACGTG in the upstream activating sequence (UAS) of genes involved in sulfur amino acid metabolism, resulting in their transcriptional activation. GO:0090702 non-reproductive fruiting body development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090702 The process whose specific outcome is the progression of a non-reproductive fruiting body over time, from its formation to the mature structure. A non-reproductive fruiting body is a colonial multicellular structure consisting of co-operating unicellular organisms, some of which are spores. An example of such a process is found in Dictyostelium discoideum and Myxococcus xanthus colonies. GO:1905544 L-methionine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905544 L-methionine import into cell The directed movement of L-methionine from outside of a cell, across the plasma membrane and into the cytosol. GO:1905545 obsolete negative regulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905545 negative regulation of regulation of ferrichrome biosynthetic process, peptide formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome formation by inhibition of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide formation by downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome formation by negative regulation of transcription from Pol II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome formation by down regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process by down-regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process by down-regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome anabolism by negative regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome anabolism by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome anabolism by down-regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide modification by downregulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide modification by inhibition of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome anabolism by down regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process by downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from Pol II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process by down regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process by inhibition of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome synthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from Pol II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from Pol II promoter in response to iron|inhibition of regulation of ferrichrome biosynthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from Pol II promoter in response to iron|downregulation of regulation of ferrichrome synthesis by negative regulation of transcription from Pol II promoter in response to iron|down regulation of regulation of ferrichrome formation by inhibition of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome formation by negative regulation of transcription from Pol II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide modification by down regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome synthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from Pol II promoter in response to iron|downregulation of regulation of ferrichrome anabolism by negative regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide formation by down regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome formation by negative regulation of transcription from Pol II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome anabolism by down-regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome synthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome synthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from Pol II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide modification by down-regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome synthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome synthesis by negative regulation of transcription from Pol II promoter in response to iron|downregulation of regulation of ferrichrome anabolism by inhibition of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome synthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide formation by downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome formation by downregulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome formation by downregulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome anabolism by negative regulation of transcription from Pol II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide formation by inhibition of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide formation by inhibition of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome synthesis by negative regulation of transcription from Pol II promoter in response to iron|negative regulation of regulation of ferrichrome formation by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide modification by downregulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome anabolism by down regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome formation by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome synthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process by down-regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide formation by down regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide modification by down-regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome synthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome synthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome synthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome formation by inhibition of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome anabolism by inhibition of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome anabolism by negative regulation of transcription from Pol II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide modification by inhibition of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide modification by inhibition of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from Pol II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from Pol II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process by inhibition of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from Pol II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from Pol II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process by inhibition of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from Pol II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome anabolism by negative regulation of transcription from Pol II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide modification by downregulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome synthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome anabolism by downregulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome synthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process by down-regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome anabolism by downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome anabolism by down-regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process by downregulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome anabolism by negative regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome anabolism by negative regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome anabolism by down-regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide modification by down regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome formation by down regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process by down-regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome formation by downregulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide modification by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from Pol II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide modification by down-regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide formation by inhibition of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from Pol II promoter in response to iron|inhibition of regulation of ferrichrome anabolism by inhibition of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide formation by downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome synthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide formation by downregulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide formation by down regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome synthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process by negative regulation of transcription from Pol II promoter in response to iron|downregulation of regulation of ferrichrome synthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide formation by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process by downregulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome synthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome synthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthesis by negative regulation of transcription from Pol II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process by down regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome formation by downregulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide formation by inhibition of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome anabolism by down regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome anabolism by down-regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome formation by downregulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide modification by downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide modification by downregulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome anabolism by negative regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome synthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome formation by inhibition of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome formation by negative regulation of transcription from Pol II promoter in response to iron|down-regulation of regulation of ferrichrome formation by negative regulation of transcription from Pol II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide modification by inhibition of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from Pol II promoter in response to iron|negative regulation of regulation of ferrichrome formation by inhibition of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome anabolism by downregulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process by inhibition of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from Pol II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide modification by down regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome anabolism by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome synthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome synthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome synthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome synthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome synthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome synthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome synthesis by negative regulation of transcription from Pol II promoter in response to iron|down-regulation of regulation of ferrichrome synthesis by negative regulation of transcription from Pol II promoter in response to iron|down regulation of regulation of ferrichrome anabolism by downregulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome formation by down regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process by downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process by downregulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide formation by downregulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide formation by inhibition of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide modification by down regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome anabolism by downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome synthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from Pol II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide modification by down-regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide modification by down-regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process by down regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome anabolism by inhibition of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide modification by inhibition of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome anabolism by inhibition of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome anabolism by negative regulation of transcription from Pol II promoter in response to iron|down-regulation of regulation of ferrichrome anabolism by negative regulation of transcription from Pol II promoter in response to iron|down regulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from Pol II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process by inhibition of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide formation by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from Pol II promoter in response to iron OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron. GO:0089714 UDP-N-acetyl-D-mannosamine dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0089714 RHEA:25780|EC:1.1.1.336 Catalysis of the reaction: UDP-N-acetyl-alpha-D-mannosamine + 2 NAD+ + H2O = UDP-N-acetyl-alpha-D-mannosaminuronate + 2 NADH + 2 H+. GO:0090700 maintenance of plant organ identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090700 The process in which the identity of a plant organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized. GO:0089715 tRNA m6t6A37 methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0089715 MetaCyc:RXN0-7114 Catalysis of the reaction: S-adenosyl-L-methionine + tRNA containing N6-threonylcarbamoyladenosine = S-adenosyl-L-homocysteine + tRNA containing N6-methylthreonylcarbamoyladenosine. GO:1905546 cellular response to phenylpropanoid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905546 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylpropanoid stimulus. GO:1905547 regulation of subtelomeric heterochromatin assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905547 regulation of telomeric heterochromatin formation|regulation of telomeric heterochromatin assembly Any process that modulates the frequency, rate or extent of subtelomeric heterochromatin assembly. GO:0089716 Pip2-Oaf1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0089716 A heterodimeric complex consisting of Zn(2)Cys(6) containing transcription factors Pip2 and Oaf1. It binds to the oleate response element (ORE), found in the promoters of fatty acid-inducible genes in Saccharomyces where, in the presence of oleate this bound complex activates the transcription of genes encoding peroxisomal proteins. GO:0090705 trichome papilla biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090705 A plant cell papilla that is part of a trichome cell. GO:1905548 negative regulation of subtelomeric heterochromatin assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905548 down-regulation of telomeric heterochromatin assembly|negative regulation of telomeric heterochromatin formation|down-regulation of telomeric heterochromatin formation|inhibition of telomeric heterochromatin formation|downregulation of telomeric heterochromatin assembly|inhibition of telomeric heterochromatin assembly|down regulation of telomeric heterochromatin assembly|negative regulation of telomeric heterochromatin assembly|down regulation of telomeric heterochromatin formation|downregulation of telomeric heterochromatin formation Any process that stops, prevents or reduces the frequency, rate or extent of subtelomeric heterochromatin assembly. GO:0089717 spanning component of membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0089717 The component of a membrane consisting of gene products and protein complexes that have some part that spans both leaflets of the membrane. GO:0090706 specification of plant organ position biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090706 The regionalization process in which information that determines the correct position at which plant organ primordia are formed is generated and perceived resulting in correct positioning of the new plant organ. GO:1905549 positive regulation of subtelomeric heterochromatin assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905549 positive regulation of telomeric heterochromatin formation|up regulation of telomeric heterochromatin assembly|up-regulation of telomeric heterochromatin formation|upregulation of telomeric heterochromatin assembly|upregulation of telomeric heterochromatin formation|positive regulation of telomeric heterochromatin assembly|activation of telomeric heterochromatin assembly|activation of telomeric heterochromatin formation|up-regulation of telomeric heterochromatin assembly|up regulation of telomeric heterochromatin formation Any process that activates or increases the frequency, rate or extent of subtelomeric heterochromatin assembly. GO:0089718 amino acid import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0089718 amino acid import into cell|L-amino acid uptake|amino acid transmembrane import|L-amino acid import The directed movement of an amino acid from outside of a cell, across the plasma membrane and into the cytosol. GO:0090703 obsolete triplex DNA unwinding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090703 OBSOLETE. The process by which a three-stranded D-loop DNA is unwound or 'melted'. GO:0090704 nicotinate-O-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090704 Catalysis of the reaction: nicotinate + UDP-D-glucose = O-D-glucosylnicotinate + UDP. GO:0089719 RHG protein domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0089719 inhibitor of apoptosis binding domain binding|RHG domain binding|reaper hid grim domain binding|iap binding domain binding Interacting selectively and non-covalently with an RHG (reaper/hid/grimm) domain/motif (AKA iap binding motif). GO:0051130 positive regulation of cellular component organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization and biogenesis|up-regulation of cell organization|upregulation of cell organization|positive regulation of cell organisation|up regulation of cell organization|activation of cell organization|stimulation of cell organization Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. GO:0051133 regulation of NK T cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051133 regulation of NK T-lymphocyte activation|regulation of NT cell activation|regulation of NK T-cell activation|regulation of natural T cell activation|regulation of natural killer T cell activation|regulation of NK T lymphocyte activation|regulation of NKT cell activation Any process that modulates the frequency, rate or extent of natural killer T cell activation. GO:0075100 obsolete positive regulation by host of symbiont protein kinase-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075100 OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of protein kinase-mediated signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051134 negative regulation of NK T cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051134 negative regulation of natural T cell activation|negative regulation of NKT cell activation|negative regulation of natural killer T cell activation|negative regulation of NK T lymphocyte activation|down-regulation of NK T cell activation|negative regulation of NK T-lymphocyte activation|downregulation of NK T cell activation|negative regulation of NT cell activation|down regulation of NK T cell activation|negative regulation of NK T-cell activation|inhibition of NK T cell activation Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell activation. GO:0075101 obsolete negative regulation by host of symbiont protein kinase-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075101 OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of protein kinase-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051131 chaperone-mediated protein complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051131 cellular chaperone-mediated protein complex assembly|chaperone activity|protein complex assembly, multichaperone pathway The aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex. GO:0075102 obsolete negative regulation by host of symbiont MAP kinase-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075102 OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont MAP kinase-mediated signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051132 NK T cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051132 natural T cell activation|NKT cell activation|natural killer T cell activation|NK T lymphocyte activation|NK T-lymphocyte activation|NT cell activation|NK T-cell activation The change in morphology and behavior of a mature or immature natural killer T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. UBERON:0008324 erectile tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008324 with numerous vascular spaces that may become engorged with blood GO:0075103 obsolete modulation by host of symbiont calcium or calmodulin-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075103 modulation by host of symbiont Ca++ or calmodulin-mediated signal transduction OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051148 negative regulation of muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051148 downregulation of muscle cell differentiation|down-regulation of muscle cell differentiation|inhibition of muscle cell differentiation|down regulation of muscle cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of muscle cell differentiation. GO:0051149 positive regulation of muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051149 up regulation of muscle cell differentiation|activation of muscle cell differentiation|stimulation of muscle cell differentiation|up-regulation of muscle cell differentiation|upregulation of muscle cell differentiation Any process that activates or increases the frequency, rate or extent of muscle cell differentiation. GO:0051146 striated muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051146 voluntary muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle. GO:0051147 regulation of muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051147 Any process that modulates the frequency, rate or extent of muscle cell differentiation. GO:0090709 regulation of timing of plant organ formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090709 Any process that modulates the rate, frequency or extent of plant organ formation at a consistent predetermined time point during development. CHEBI:26133 pinane monoterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26133 GO:0090707 establishment of plant organ orientation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090707 The process that determines the orientation of a plant organ or tissue with reference to an axis. GO:1905560 negative regulation of kinetochore assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905560 down-regulation of centromere/kinetochore complex maturation|negative regulation of centromere/kinetochore complex maturation|down regulation of chromosome-kinetochore attachment|down-regulation of kinetochore formation|negative regulation of centromere and kinetochore complex maturation|down-regulation of centromere and kinetochore complex maturation|negative regulation of kinetochore formation|downregulation of chromosome-kinetochore attachment|down-regulation of kinetochore assembly|inhibition of centromere/kinetochore complex maturation|negative regulation of chromosome-kinetochore attachment|down-regulation of chromosome-kinetochore attachment|inhibition of centromere and kinetochore complex maturation|inhibition of kinetochore formation|down regulation of centromere/kinetochore complex maturation|downregulation of kinetochore assembly|downregulation of centromere/kinetochore complex maturation|down regulation of kinetochore assembly|down regulation of kinetochore formation|down regulation of centromere and kinetochore complex maturation|inhibition of kinetochore assembly|inhibition of chromosome-kinetochore attachment|downregulation of kinetochore formation|down regulation of kinetochore biogenesis|downregulation of centromere and kinetochore complex maturation Any process that stops, prevents or reduces the frequency, rate or extent of kinetochore assembly. GO:0090708 specification of plant organ axis polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090708 The process in which the polarity of a plant organ axis is specified. GO:1905561 positive regulation of kinetochore assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905561 upregulation of chromosome-kinetochore attachment|up regulation of kinetochore formation|up regulation of centromere and kinetochore complex maturation|activation of centromere/kinetochore complex maturation|positive regulation of kinetochore formation|positive regulation of centromere and kinetochore complex maturation|up-regulation of kinetochore assembly|activation of kinetochore assembly|activation of centromere and kinetochore complex maturation|up-regulation of centromere/kinetochore complex maturation|activation of kinetochore formation|up regulation of chromosome-kinetochore attachment|positive regulation of chromosome-kinetochore attachment|up-regulation of kinetochore formation|up-regulation of centromere and kinetochore complex maturation|upregulation of centromere/kinetochore complex maturation|activation of chromosome-kinetochore attachment|up regulation of kinetochore assembly|upregulation of centromere and kinetochore complex maturation|up-regulation of chromosome-kinetochore attachment|upregulation of kinetochore formation|up regulation of centromere/kinetochore complex maturation|upregulation of kinetochore assembly|positive regulation of centromere/kinetochore complex maturation Any process that activates or increases the frequency, rate or extent of kinetochore assembly. GO:1905562 regulation of vascular endothelial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905562 Any process that modulates the frequency, rate or extent of vascular endothelial cell proliferation. GO:0089720 caspase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0089720 Interacting selectively and non-covalently with a caspase family protein. GO:1905563 negative regulation of vascular endothelial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905563 inhibition of vascular endothelial cell proliferation|down regulation of vascular endothelial cell proliferation|downregulation of vascular endothelial cell proliferation|down-regulation of vascular endothelial cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial cell proliferation. GO:0089721 phosphoenolpyruvate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0089721 Enables the transfer of a phosphoenolpyruvate from one side of a membrane to the other. CHEBI:26130 biological pigment biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26130 GO:1905564 positive regulation of vascular endothelial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905564 up-regulation of vascular endothelial cell proliferation|upregulation of vascular endothelial cell proliferation|up regulation of vascular endothelial cell proliferation|activation of vascular endothelial cell proliferation Any process that activates or increases the frequency, rate or extent of vascular endothelial cell proliferation. GO:0089722 phosphoenolpyruvate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0089722 The directed movement of phosphoenolpytuvate across a membrane. GO:1905554 negative regulation of vessel branching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905554 downregulation of branching involved in blood vessel morphogenesis|down regulation of branching involved in blood vessel morphogenesis|inhibition of branching involved in blood vessel morphogenesis|down regulation of patterning of blood vessels|downregulation of patterning of blood vessels|down-regulation of patterning of blood vessels|negative regulation of branching involved in blood vessel morphogenesis|down-regulation of branching involved in blood vessel morphogenesis|inhibition of patterning of blood vessels Any process that stops, prevents or reduces the frequency, rate or extent of blood vessel branching. GO:0090712 basal pole of outer hair cell biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090712 The end of the outer hair cell which receives and transmits neural signals. GO:0090713 immunological memory process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090713 Any process of the immune system that can contribute to the formation of immunological memory or an immune response based upon activation of immunological memory. GO:1905555 positive regulation of blood vessel branching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905555 upregulation of patterning of blood vessels|upregulation of branching involved in blood vessel morphogenesis|up regulation of patterning of blood vessels|up-regulation of branching involved in blood vessel morphogenesis|activation of branching involved in blood vessel morphogenesis|activation of patterning of blood vessels|positive regulation of branching involved in blood vessel morphogenesis|up-regulation of patterning of blood vessels|up regulation of branching involved in blood vessel morphogenesis Any process that activates or increases the frequency, rate or extent of blood vessel branching. GO:1905556 ciliary vesicle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905556 primary ciliary vesicle formation|CV assembly|ciliary vesicle formation|primary ciliary vesicle assembly|CV formation The aggregation, arrangement and bonding together of a set of components to form a ciliary vesicle. Multiple smaller vesicles dock to the transitional fibers on a mature basal body and then fuse together to form a larger single vesicle. This then fuses with the plasma membrane and forms the ciliary membrane. GO:0090710 phosphomevalonate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090710 Catalysis of the reaction: ATP + (R)-mevalonate 5-phosphate = ADP + isopentenyl phosphate + CO2 + phosphate. GO:0090711 FMN hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090711 Catalysis of the reaction: FMN + H2O = riboflavin + phosphate. GO:1905557 regulation of mitotic nuclear envelope disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905557 regulation of mitotic nuclear envelope degradation|regulation of mitotic nuclear envelope catabolism|regulation of mitotic nuclear envelope breakdown Any process that modulates the frequency, rate or extent of mitotic nuclear envelope disassembly. GO:1905558 negative regulation of mitotic nuclear envelope disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905558 inhibition of mitotic nuclear envelope catabolism|down regulation of mitotic nuclear envelope disassembly|negative regulation of mitotic nuclear envelope degradation|inhibition of mitotic nuclear envelope disassembly|down-regulation of mitotic nuclear envelope degradation|down-regulation of mitotic nuclear envelope breakdown|negative regulation of mitotic nuclear envelope breakdown|downregulation of mitotic nuclear envelope degradation|down regulation of mitotic nuclear envelope catabolism|down regulation of mitotic nuclear envelope degradation|inhibition of mitotic nuclear envelope degradation|downregulation of mitotic nuclear envelope breakdown|downregulation of mitotic nuclear envelope catabolism|down regulation of mitotic nuclear envelope breakdown|down-regulation of mitotic nuclear envelope disassembly|inhibition of mitotic nuclear envelope breakdown|negative regulation of mitotic nuclear envelope catabolism|down-regulation of mitotic nuclear envelope catabolism|downregulation of mitotic nuclear envelope disassembly Any process that stops, prevents or reduces the frequency, rate or extent of mitotic nuclear envelope disassembly. GO:0090716 adaptive immune memory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090716 An immune response directed against a previously encountered antigen, being quicker and quantitatively better compared with the primary response. GO:0090717 adaptive immune memory response involving T cells and B cells biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090717 An immune response mediated by reactivated memory T cells and B cells and directed against a previously encountered antigen, being quicker and quantitatively better compared with the primary response. GO:1905559 positive regulation of mitotic nuclear envelope disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905559 activation of mitotic nuclear envelope breakdown|up-regulation of mitotic nuclear envelope catabolism|upregulation of mitotic nuclear envelope disassembly|positive regulation of mitotic nuclear envelope degradation|up regulation of mitotic nuclear envelope degradation|upregulation of mitotic nuclear envelope catabolism|positive regulation of mitotic nuclear envelope breakdown|up regulation of mitotic nuclear envelope breakdown|up-regulation of mitotic nuclear envelope disassembly|activation of mitotic nuclear envelope disassembly|upregulation of mitotic nuclear envelope degradation|up regulation of mitotic nuclear envelope catabolism|activation of mitotic nuclear envelope catabolism|upregulation of mitotic nuclear envelope breakdown|positive regulation of mitotic nuclear envelope catabolism|up regulation of mitotic nuclear envelope disassembly|up-regulation of mitotic nuclear envelope degradation|activation of mitotic nuclear envelope degradation|up-regulation of mitotic nuclear envelope breakdown Any process that activates or increases the frequency, rate or extent of mitotic nuclear envelope disassembly. GO:0090714 innate immunity memory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090714 An immune response mediated by the innate immune system and directed against a previously encountered immunologic stimulus, being quicker and quantitatively better compared with the initial response to that stimulus. GO:0090715 immunological memory formation process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090715 Any immunological memory process that can contribute to the formation of immunological memory. GO:0051140 regulation of NK T cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051140 regulation of NK T-cell proliferation|regulation of NT cell proliferation|regulation of NK T-lymphocyte proliferation|regulation of NKT cell proliferation|regulation of NK T lymphocyte proliferation|regulation of natural killer T cell proliferation|regulation of natural T cell proliferation Any process that modulates the frequency, rate or extent of natural killer T cell proliferation. GO:0051141 negative regulation of NK T cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051141 down-regulation of NK T cell proliferation|negative regulation of NK T lymphocyte proliferation|negative regulation of natural killer T cell proliferation|inhibition of NK T cell proliferation|negative regulation of NKT cell proliferation|negative regulation of natural T cell proliferation|down regulation of NK T cell proliferation|negative regulation of NK T-cell proliferation|negative regulation of NT cell proliferation|downregulation of NK T cell proliferation|negative regulation of NK T-lymphocyte proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell proliferation. GO:0051144 propanediol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051144 propanediol degradation|1,2-dihydroxypropane catabolic process|propanediol catabolism|propanediol breakdown|1,2-dihydroxypropane catabolism|propylene glycol catabolism|propylene glycol catabolic process The chemical reactions and pathways resulting in the breakdown of propanediol, a sweet, colorless, viscous, hygroscopic liquid with the formula CH3-CHOH-CH2OH. UBERON:0008310 nasopharyngeal gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008310 A gland that is part of a nasopharynx. GO:0051145 smooth muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051145 nonstriated muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary. GO:0051142 positive regulation of NK T cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051142 stimulation of NK T cell proliferation|positive regulation of NK T lymphocyte proliferation|positive regulation of natural killer T cell proliferation|up-regulation of NK T cell proliferation|positive regulation of NKT cell proliferation|positive regulation of NK T-cell proliferation|upregulation of NK T cell proliferation|positive regulation of NT cell proliferation|positive regulation of NK T-lymphocyte proliferation|positive regulation of natural T cell proliferation|up regulation of NK T cell proliferation|activation of NK T cell proliferation Any process that activates or increases the frequency, rate or extent of natural killer T cell proliferation. GO:0051143 propanediol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051143 propanediol metabolism|1,2-dihydroxypropane metabolism|propylene glycol metabolic process|propylene glycol metabolism|1,2-dihydroxypropane metabolic process The chemical reactions and pathways involving propanediol, CH3-CHOH-CH2OH, a sweet, colorless, viscous, hygroscopic liquid used as an antifreeze, in brake fluid and as a humectant in cosmetics and personal care items. GO:2000948 regulation of xyloglucan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000948 regulation of xyloglucan metabolism Any process that modulates the frequency, rate or extent of xyloglucan metabolic process. GO:0051159 D-arabitol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051159 D-arabitol catabolism|D-arabitol degradation|D-arabitol breakdown The chemical reactions and pathways resulting in the breakdown of D-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms. GO:0075126 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075126 GO:2000949 negative regulation of xyloglucan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000949 negative regulation of xyloglucan metabolism Any process that stops, prevents or reduces the frequency, rate or extent of xyloglucan metabolic process. GO:0075127 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075127 GO:0051157 arabitol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051157 arabitol degradation|arabitol breakdown|arabitol catabolism|arabitol utilization The chemical reactions and pathways resulting in the breakdown of arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. GO:0110058 positive regulation of blood vessel endothelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110058 Any process that activates or increases the frequency, rate or extent of blood vessel endothelial cell differentiation. GO:0075128 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075128 GO:0051158 L-arabitol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051158 L-arabitol degradation|L-arabitol breakdown|L-arabitol catabolism The chemical reactions and pathways resulting in the breakdown of L-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. GO:0110059 negative regulation of blood vessel endothelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110059 Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel endothelial cell differentiation. GO:0075129 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075129 GO:0110056 positive regulation of actin filament annealing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110056 Any process that activates or increases the frequency, rate or extent of actin filament annealing, i.e. the end-to-end joining of existing actin filaments. GO:0110057 regulation of blood vessel endothelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110057 Any process that modulates the frequency, rate or extent of blood vessel endothelial cell differentiation. GO:0110054 regulation of actin filament annealing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110054 Any process that modulates the frequency, rate or extent of actin filament annealing, i.e. the end-to-end joining of existing actin filaments. GO:0110055 negative regulation of actin filament annealing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110055 Any process that stops, prevents or reduces the frequency, rate or extent of actin filament annealing, i.e. the end-to-end joining of existing actin filaments. CHEBI:26106 phylloquinones biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26106 GO:2000940 negative regulation of plant-type cell wall cellulose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000940 negative regulation of plant-type cell wall polysaccharide breakdown Any process that stops, prevents or reduces the frequency, rate or extent of plant-type cell wall cellulose catabolic process. GO:0110052 toxic metabolite repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110052 A cellular process that, through single- or multi-step enzymatic reactions, repairs toxic endogenous compounds, formed as by-products of primary metabolism, by converting them into useful metabolites. GO:0110053 regulation of actin filament organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110053 Any process that modulates the frequency, rate or extent of actin filament organization. GO:2000941 positive regulation of plant-type cell wall cellulose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000941 positive regulation of plant-type cell wall polysaccharide breakdown Any process that activates or increases the frequency, rate or extent of plant-type cell wall cellulose catabolic process. GO:1905570 positive regulation of ferrichrome biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905570 up-regulation of ferrichrome formation|upregulation of ferrichrome anabolism|up-regulation of ferrichrome biosynthesis|up-regulation of ferrichrome biosynthetic process|activation of ferrichrome biosynthetic process|activation of ferrichrome biosynthetic process, peptide formation|activation of ferrichrome biosynthesis|activation of ferrichrome biosynthetic process, peptide modification|upregulation of ferrichrome synthesis|upregulation of ferrichrome formation|up-regulation of ferrichrome biosynthetic process, peptide formation|positive regulation of ferrichrome biosynthetic process, peptide modification|up regulation of ferrichrome biosynthetic process, peptide modification|up regulation of ferrichrome anabolism|positive regulation of ferrichrome anabolism|positive regulation of ferrichrome biosynthesis|activation of ferrichrome anabolism|up regulation of ferrichrome biosynthesis|up regulation of ferrichrome synthesis|up regulation of ferrichrome biosynthetic process|positive regulation of ferrichrome synthesis|activation of ferrichrome synthesis|upregulation of ferrichrome biosynthetic process, peptide formation|up regulation of ferrichrome formation|positive regulation of ferrichrome formation|activation of ferrichrome formation|upregulation of ferrichrome biosynthetic process, peptide modification|up-regulation of ferrichrome anabolism|upregulation of ferrichrome biosynthetic process|upregulation of ferrichrome biosynthesis|up regulation of ferrichrome biosynthetic process, peptide formation|up-regulation of ferrichrome synthesis|up-regulation of ferrichrome biosynthetic process, peptide modification|positive regulation of ferrichrome biosynthetic process, peptide formation Any process that activates or increases the frequency, rate or extent of ferrichrome biosynthetic process. GO:0110050 deaminated glutathione amidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0110050 Catalysis of the reaction: N-(4-oxoglutarate)-L-cysteinylglycine + H(2)O = 2-oxoglutarate + L-cysteinylglycine. GO:2000942 regulation of amylopectin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000942 regulation of Amylopectin metabolism Any process that modulates the frequency, rate or extent of amylopectin metabolic process. GO:0110051 metabolite repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110051 A cellular process that, through single- or multi-step enzymatic reactions, repairs useless or toxic endogenous compounds, formed as by-products of primary metabolism, by converting them into useful metabolites. GO:1905571 interleukin-10 receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1905571 interleukin-10-receptor complex|IL-10-receptor complex|IL10 receptor complex|IL-10 receptor complex A protein complex that binds interleukin-10 (IL-10) and that consists of, at a minimum, a dimeric interleukin, an alpha and a beta chain as well as optional additional kinase subunits. The alpha chain binds IL-10 with high affinity and subsequently binds the common beta receptor chain that forms part of multiple interleukin receptors. GO:2000943 negative regulation of amylopectin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000943 negative regulation of Amylopectin metabolism Any process that stops, prevents or reduces the frequency, rate or extent of amylopectin metabolic process. GO:1905572 ganglioside GM1 transport to membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905572 The directed movement of ganglioside GM1 to membrane. GO:2000944 positive regulation of amylopectin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000944 positive regulation of Amylopectin metabolism Any process that activates or increases the frequency, rate or extent of amylopectin metabolic process. GO:2000945 regulation of amylopectin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000945 regulation of Amylopectin catabolism Any process that modulates the frequency, rate or extent of amylopectin catabolic process. GO:1905573 ganglioside GM1 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1905573 Interacting selectively and non-covalently with ganglioside GM1. GO:2000946 negative regulation of amylopectin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000946 negative regulation of Amylopectin catabolism Any process that stops, prevents or reduces the frequency, rate or extent of amylopectin catabolic process. GO:1905574 ganglioside GM2 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1905574 Interacting selectively and non-covalently with ganglioside GM2. GO:2000947 positive regulation of amylopectin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000947 positive regulation of Amylopectin catabolism Any process that activates or increases the frequency, rate or extent of amylopectin catabolic process. GO:1905575 ganglioside GM3 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1905575 Interacting selectively and non-covalently with ganglioside GM3. GO:1905565 obsolete regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905565 regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|regulation of receptor-mediated endocytosis of LDL OBSOLETE. Any process that modulates the frequency, rate or extent of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport. GO:1905566 obsolete negative regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905566 down regulation of receptor-mediated endocytosis of LDL|negative regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|down-regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|inhibition of receptor-mediated endocytosis of LDL|inhibition of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|downregulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|down regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|down regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|down-regulation of receptor-mediated endocytosis of LDL|downregulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|negative regulation of receptor-mediated endocytosis of LDL|inhibition of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|down-regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|downregulation of receptor-mediated endocytosis of LDL OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport. GO:1905567 obsolete positive regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905567 activation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|up-regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|upregulation of receptor-mediated endocytosis of LDL|positive regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|up regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|up-regulation of receptor-mediated endocytosis of LDL|upregulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|activation of receptor-mediated endocytosis of LDL|upregulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|up regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|positive regulation of receptor-mediated endocytosis of LDL|activation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|up regulation of receptor-mediated endocytosis of LDL|up-regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport OBSOLETE. Any process that activates or increases the frequency, rate or extent of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport. GO:1905568 regulation of ferrichrome biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905568 regulation of ferrichrome synthesis|regulation of ferrichrome formation|regulation of ferrichrome biosynthetic process, peptide modification|regulation of ferrichrome biosynthesis|regulation of ferrichrome biosynthetic process, peptide formation|regulation of ferrichrome anabolism Any process that modulates the frequency, rate or extent of ferrichrome biosynthetic process. GO:1905569 negative regulation of ferrichrome biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905569 negative regulation of ferrichrome biosynthesis|down-regulation of ferrichrome biosynthesis|down-regulation of ferrichrome biosynthetic process|down regulation of ferrichrome formation|downregulation of ferrichrome synthesis|downregulation of ferrichrome biosynthetic process, peptide modification|inhibition of ferrichrome biosynthetic process, peptide formation|downregulation of ferrichrome formation|down-regulation of ferrichrome anabolism|negative regulation of ferrichrome anabolism|downregulation of ferrichrome biosynthesis|down regulation of ferrichrome biosynthetic process, peptide modification|downregulation of ferrichrome biosynthetic process|down regulation of ferrichrome biosynthetic process, peptide formation|down-regulation of ferrichrome synthesis|negative regulation of ferrichrome synthesis|down regulation of ferrichrome biosynthesis|down regulation of ferrichrome biosynthetic process|down-regulation of ferrichrome formation|inhibition of ferrichrome biosynthesis|inhibition of ferrichrome biosynthetic process|negative regulation of ferrichrome formation|inhibition of ferrichrome anabolism|downregulation of ferrichrome biosynthetic process, peptide formation|inhibition of ferrichrome biosynthetic process, peptide modification|inhibition of ferrichrome synthesis|inhibition of ferrichrome formation|negative regulation of ferrichrome biosynthetic process, peptide formation|down-regulation of ferrichrome biosynthetic process, peptide formation|down regulation of ferrichrome anabolism|down-regulation of ferrichrome biosynthetic process, peptide modification|negative regulation of ferrichrome biosynthetic process, peptide modification|down regulation of ferrichrome synthesis|downregulation of ferrichrome anabolism Any process that stops, prevents or reduces the frequency, rate or extent of ferrichrome biosynthetic process. CHEBI:16777 berbamunine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16777 CHEBI:16778 apigenin 7-O-beta-D-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16778 CHEBI:16775 3-aci-nitropropanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16775 CHEBI:16776 tabersonine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16776 GO:0051151 negative regulation of smooth muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051151 down-regulation of smooth muscle cell differentiation|downregulation of smooth muscle cell differentiation|down regulation of smooth muscle cell differentiation|inhibition of smooth muscle cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell differentiation. CHEBI:16773 trans-2-chloro-4-carboxymethylenebut-2-en-1,4-olide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16773 GO:0051152 positive regulation of smooth muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051152 stimulation of smooth muscle cell differentiation|up-regulation of smooth muscle cell differentiation|activation of smooth muscle cell differentiation|up regulation of smooth muscle cell differentiation|upregulation of smooth muscle cell differentiation Any process that activates or increases the frequency, rate or extent of smooth muscle cell differentiation. CHEBI:16774 (2-cis,6-trans)-farnesol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16774 GO:0075120 suppression by symbiont of host G protein-coupled receptor signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075120 negative regulation by symbiont of host G-protein coupled receptor protein signal transduction|negative regulation by symbiont of host G protein-coupled receptor signal transduction|negative regulation by symbiont of host signal transduction mediated by G-protein alpha subunit|negative regulation by symbiont of host signal transduction mediated by G-protein beta subunit|negative regulation by symbiont of host signal transduction mediated by G-protein gamma subunit Any process in which the symbiont stops, prevents, or reduces the frequency, rate or extent of the host G protein-coupled receptor signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:16771 adenosine 5'-phosphoramidate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16771 GO:0051150 regulation of smooth muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051150 Any process that modulates the frequency, rate or extent of smooth muscle cell differentiation. GO:0075121 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075121 CHEBI:16772 xylitol 5-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16772 GO:0051155 positive regulation of striated muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051155 upregulation of striated muscle cell differentiation|stimulation of striated muscle cell differentiation|up-regulation of striated muscle cell differentiation|activation of striated muscle cell differentiation|up regulation of striated muscle cell differentiation Any process that activates or increases the frequency, rate or extent of striated muscle cell differentiation. GO:0075122 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075122 GO:0051156 glucose 6-phosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051156 glucose 6-phosphate utilization|glucose 6-phosphate metabolism The chemical reactions and pathways involving glucose 6-phosphate, a monophosphorylated derivative of glucose with the phosphate group attached to C-6. GO:0075123 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075123 CHEBI:16770 N(5)-(L-1-carboxyethyl)-L-ornithine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16770 GO:0075124 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075124 GO:0051153 regulation of striated muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051153 Any process that modulates the frequency, rate or extent of striated muscle cell differentiation. GO:0051154 negative regulation of striated muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051154 inhibition of striated muscle cell differentiation|down-regulation of striated muscle cell differentiation|downregulation of striated muscle cell differentiation|down regulation of striated muscle cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle cell differentiation. GO:0075125 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075125 GO:2000959 positive regulation of cyclodextrin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000959 positive regulation of cyclodextrin catabolism Any process that activates or increases the frequency, rate or extent of cyclodextrin catabolic process. GO:0075115 obsolete modulation by symbiont of host transmembrane receptor-mediated cAMP signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075115 modulation by symbiont of host transmembrane receptor-mediated cAMP signaling OBSOLETE. Any process in which the symbiont modulates the frequency, rate or extent of host transmembrane receptor-mediated cAMP signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0099104 potassium channel activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0099104 Direct interaction with a potassium channel (binding or modification), resulting in its opening. CHEBI:26118 phytoecdysteroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26118 GO:0099105 ion channel modulating, G protein-coupled receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099105 ion channel modulating, G-protein coupled receptor signaling pathway The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through activation or inhibition of an ion channel. GO:0075116 obsolete induction by symbiont of host transmembrane receptor-mediated cAMP signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075116 positive regulation by symbiont of host transmembrane receptor-mediated cAMP signaling|activation by symbiont of host transmembrane receptor-mediated cAMP signal transduction|positive regulation by symbiont of host transmembrane receptor-mediated cAMP signal transduction|stimulation by symbiont of host transmembrane receptor-mediated cAMP signal transduction|promotion by symbiont of host transmembrane receptor-mediated cAMP signal transduction|upregulation by symbiont of host transmembrane receptor-mediated cAMP signal transduction OBSOLETE. Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of host transmembrane receptor-mediated cAMP signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:26119 phytoene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_26119 GO:0051168 nuclear export biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051168 substance nuclear export|export from nucleus|nucleus export The directed movement of substances out of the nucleus. GO:0075117 obsolete suppression by symbiont of host transmembrane receptor-mediated cAMP signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075117 downregulation by symbiont of host transmembrane receptor-mediated cAMP signal transduction|negative regulation by symbiont of host transmembrane receptor-mediated cAMP signaling|inhibition by symbiont of host transmembrane receptor-mediated cAMP signal transduction OBSOLETE. Any process in which the symbiont stops, prevents, or reduces the frequency, rate or extent of host transmembrane receptor-mediated cAMP signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0110069 syncytial embryo cellularization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110069 The separation of a syncytial embryo into individual cells. GO:0099102 G-protein gated potassium channel activity involved in regulation of postsynaptic membrane potential biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099102 Any G-protein gated potassium channel activity that is involved regulation of postsynaptic membrane potential. GO:0075118 modulation by symbiont of host G protein-coupled receptor signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075118 modulation by symbiont of host signal transduction mediated by G-protein gamma subunit|modulation by symbiont of host signal transduction mediated by G-protein beta subunit|modulation by symbiont of host signal transduction mediated by G-protein alpha subunit|modulation by symbiont of host G-protein coupled receptor protein signal transduction Any process in which the symbiont modulates the frequency, rate or extent of the host G protein-coupled receptor signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051169 nuclear transport biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0051169 Wikipedia:Nuclear_transport nucleus transport The directed movement of substances into, out of, or within the nucleus. GO:0099103 channel activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0099103 channel gating activity Direct interaction with a channel (binding or modification), resulting in its opening. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. GO:0075119 induction by symbiont of host G protein-coupled receptor signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075119 positive regulation by symbiont of host signal transduction mediated by G-protein alpha subunit|positive regulation by symbiont of host signal transduction mediated by G-protein beta subunit|positive regulation by symbiont of host G-protein coupled receptor protein signal transduction|positive regulation by symbiont of host G protein-coupled receptor signal transduction|positive regulation by symbiont of host signal transduction mediated by G-protein gamma subunit Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of the host G protein-coupled receptor signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0110067 ammonium transmembrane transporter complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0110067 IntAct:EBI-16426073 AMT1 complex High affinity ammonium transporter complex that enables the transfer of ammonium from one side of a membrane to the other. GO:0099100 G-protein gated cation channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0099100 A cation channel activity that is gated by binding of a G-protein beta-gamma dimer. GO:0099101 G-protein gated potassium channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0099101 A potassium channel activity that is gated by binding of a G-protein beta-gamma dimer. CHEBI:26115 phytoalexin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26115 GO:0110068 glucosylglycerate phosphorylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0110068 Catalysis of the reaction: glucosylglycerate + phosphate = glucose-1-phosphate + D-glycerate. GO:0110065 regulation of interphase mitotic telomere clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110065 regulation of mitotic telomere clustering during interphase Any process that modulates the frequency, rate or extent of mitotic telomere clustering during interphase. CHEBI:26116 phytochromobilin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26116 GO:0110066 negative regulation of interphase mitotic telomere clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110066 negative regulation of mitotic telomere clustering during interphase|telomere dispersion during interphase Any process that stops, prevents, or reduces the frequency, rate or extent of mitotic telomere clustering during interphase. GO:2000951 regulation of xyloglucan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000951 regulation of xyloglucan catabolism Any process that modulates the frequency, rate or extent of xyloglucan catabolic process. GO:0110063 positive regulation of angiotensin-activated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110063 Any process that activates or increases the frequency, rate or extent of the angiotensin-activated signaling pathway. GO:1905580 positive regulation of ERBB3 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905580 upregulation of ERBB3 signaling pathway|positive regulation of ERBB3 signalling pathway|positive regulation of HER3 signaling pathway|up regulation of HER3 signaling pathway|up regulation of ERBB3 signalling pathway|up-regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway|up regulation of ERBB3 signaling pathway|upregulation of ERBB3 signalling pathway|upregulation of HER3 signaling pathway|activation of ERBB3 signaling pathway|upregulation of receptor tyrosine-protein kinase erbB-3 signaling pathway|up-regulation of HER3 signaling pathway|up-regulation of ERBB3 signalling pathway|activation of ERBB3 signalling pathway|activation of HER3 signaling pathway|up regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway|up-regulation of ERBB3 signaling pathway|positive regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway|activation of receptor tyrosine-protein kinase erbB-3 signaling pathway Any process that activates or increases the frequency, rate or extent of ERBB3 signaling pathway. GO:2000952 negative regulation of xyloglucan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000952 negative regulation of xyloglucan catabolism Any process that stops, prevents or reduces the frequency, rate or extent of xyloglucan catabolic process. GO:0110064 lncRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110064 lncRNA catabolism|lncRNA degradation|lncRNA breakdown The chemical reactions and pathways resulting in the breakdown of lncRNAs, non-coding RNAs over 200 nucleotides in length. GO:1905581 positive regulation of low-density lipoprotein particle clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905581 upregulation of low-density lipoprotein particle clearance|up regulation of LDL clearance|activation of LDL clearance|positive regulation of LDL clearance|up-regulation of low-density lipoprotein particle clearance|activation of low-density lipoprotein particle clearance|up-regulation of LDL clearance|up regulation of low-density lipoprotein particle clearance|upregulation of LDL clearance Any process that activates or increases the frequency, rate or extent of low-density lipoprotein particle clearance. GO:2000953 positive regulation of xyloglucan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000953 positive regulation of xyloglucan catabolism Any process that activates or increases the frequency, rate or extent of xyloglucan catabolic process. GO:0110061 regulation of angiotensin-activated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110061 Any process that modulates the frequency, rate or extent of the angiotensin-activated signaling pathway. GO:0110062 negative regulation of angiotensin-activated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110062 Any process that stops, prevents, or reduces the frequency, rate or extent of the angiotensin-activated signaling pathway. GO:1905582 response to mannose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905582 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannose stimulus. GO:2000954 regulation of cyclodextrin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000954 regulation of cyclodextrin metabolism Any process that modulates the frequency, rate or extent of cyclodextrin metabolic process. GO:1905583 cellular response to mannose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905583 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannose stimulus. GO:2000955 negative regulation of cyclodextrin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000955 negative regulation of cyclodextrin metabolism Any process that stops, prevents or reduces the frequency, rate or extent of cyclodextrin metabolic process. GO:1905584 outer hair cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905584 outer hair cell apoptosis|cochlear outer hair cell apoptosis|cochlear outer hair cell apoptotic process Any apoptotic process in an outer hair cell. GO:2000956 positive regulation of cyclodextrin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000956 positive regulation of cyclodextrin metabolism Any process that activates or increases the frequency, rate or extent of cyclodextrin metabolic process. GO:1905585 regulation of outer hair cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905585 regulation of cochlear outer hair cell apoptosis|regulation of outer hair cell apoptosis|regulation of cochlear outer hair cell apoptotic process Any process that modulates the frequency, rate or extent of outer hair cell apoptotic process. GO:2000957 regulation of cyclodextrin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000957 regulation of cyclodextrin catabolism Any process that modulates the frequency, rate or extent of cyclodextrin catabolic process. GO:1905586 negative regulation of outer hair cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905586 down regulation of outer hair cell apoptosis|down regulation of cochlear outer hair cell apoptosis|downregulation of outer hair cell apoptosis|downregulation of cochlear outer hair cell apoptotic process|down regulation of outer hair cell apoptotic process|down regulation of cochlear outer hair cell apoptotic process|downregulation of outer hair cell apoptotic process|inhibition of cochlear outer hair cell apoptosis|inhibition of cochlear outer hair cell apoptotic process|down-regulation of outer hair cell apoptosis|negative regulation of outer hair cell apoptosis|down-regulation of outer hair cell apoptotic process|negative regulation of cochlear outer hair cell apoptosis|down-regulation of cochlear outer hair cell apoptosis|inhibition of outer hair cell apoptotic process|inhibition of outer hair cell apoptosis|down-regulation of cochlear outer hair cell apoptotic process|negative regulation of cochlear outer hair cell apoptotic process|downregulation of cochlear outer hair cell apoptosis Any process that stops, prevents or reduces the frequency, rate or extent of outer hair cell apoptotic process. GO:2000958 negative regulation of cyclodextrin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000958 negative regulation of cyclodextrin catabolism Any process that stops, prevents or reduces the frequency, rate or extent of cyclodextrin catabolic process. GO:1905576 ganglioside GT1b binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1905576 Interacting selectively and non-covalently with ganglioside GT1b. GO:1905577 ganglioside GP1c binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1905577 Interacting selectively and non-covalently with ganglioside GP1c. GO:1905578 regulation of ERBB3 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905578 regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway|regulation of HER3 signaling pathway|regulation of ERBB3 signalling pathway Any process that modulates the frequency, rate or extent of ERBB3 signaling pathway. CHEBI:16768 mycothiol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16768 GO:1905579 negative regulation of ERBB3 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905579 down regulation of ERBB3 signalling pathway|down regulation of HER3 signaling pathway|inhibition of ERBB3 signalling pathway|inhibition of HER3 signaling pathway|down-regulation of ERBB3 signaling pathway|down regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway|downregulation of receptor tyrosine-protein kinase erbB-3 signaling pathway|inhibition of ERBB3 signaling pathway|negative regulation of ERBB3 signalling pathway|down-regulation of ERBB3 signalling pathway|down-regulation of HER3 signaling pathway|negative regulation of HER3 signaling pathway|down-regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway|negative regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway|down regulation of ERBB3 signaling pathway|inhibition of receptor tyrosine-protein kinase erbB-3 signaling pathway|downregulation of ERBB3 signalling pathway|downregulation of HER3 signaling pathway|downregulation of ERBB3 signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of ERBB3 signaling pathway. CHEBI:16769 2-oxoglutaramate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16769 CHEBI:16766 4-carboxymethyl-4-methylbut-2-en-1,4-olide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16766 CHEBI:16767 3,4-dichloroaniline biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16767 CHEBI:16764 2'-deoxy-5-methyl-5'-cytidylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16764 GO:2000950 positive regulation of xyloglucan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000950 positive regulation of xyloglucan metabolism Any process that activates or increases the frequency, rate or extent of xyloglucan metabolic process. CHEBI:16765 tryptamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16765 GO:0051162 L-arabitol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051162 L-arabitol metabolism The chemical reactions and pathways involving L-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. CHEBI:16763 2-oxobutanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16763 GO:0051163 D-arabitol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051163 D-arabitol metabolism The chemical reactions and pathways involving D-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms. GO:0051160 L-xylitol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051160 L-xylitol degradation|L-xylitol breakdown|L-xylitol catabolism The chemical reactions and pathways resulting in the breakdown of L-xylitol, a five-carbon sugar alcohol derived from xylose by reduction of the carbonyl group. CHEBI:16760 phenanthrene-3,4-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16760 GO:0075110 induction by symbiont of host receptor-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075110 positive regulation by symbiont of host receptor-mediated signal transduction Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051161 arabitol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051161 arabitol metabolism The chemical reactions and pathways involving arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. CHEBI:16761 ADP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16761 GO:0075111 suppression by symbiont of host receptor-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075111 negative regulation by symbiont of host receptor-mediated signal transduction Any process in which the symbiont stops, prevents, or reduces the frequency, rate or extent of receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051166 2,5-dihydroxypyridine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051166 2,5-dihydroxypyridine degradation|pyridine-2,5-diol catabolic process|2,5-dihydroxypyridine catabolism|2,5-dihydroxypyridine breakdown The chemical reactions and pathways resulting in the breakdown of 2,5-dihydroxypyridine. GO:0099108 potassium channel activator activity involved in G protein-coupled receptor signaling pathway biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099108 potassium channel activator activity involved in G-protein coupled receptor signaling pathway Activation potassium ion channel activity via direct interaction with a potassium ion channel during G protein-coupled receptor signaling. GO:0075112 modulation by symbiont of host transmembrane receptor-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075112 Any process in which the symbiont modulates the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051167 xylulose 5-phosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051167 D-xylulose 5-phosphate metabolism|xylulose-5-phosphate metabolic process|D-xylulose 5-phosphate metabolic process|xylulose-5-phosphate metabolism|D-xylulose-5-phosphate metabolism|xylulose 5-phosphate metabolism|D-xylulose-5-phosphate metabolic process The chemical reactions and pathways involving xylulose 5-phosphate, a derivative of the ketopentose xylulose phosphorylated at the 5 carbon; it is an intermediate in the pentose phosphate pathway. GO:0099109 potassium channel activating, G protein-coupled receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099109 potassium channel activating, G-protein coupled receptor signaling pathway The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds activation of a potassium ion channel. GO:0075113 induction by symbiont of host transmembrane receptor-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075113 positive regulation by symbiont of host transmembrane receptor-mediated signal transduction Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051164 L-xylitol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051164 L-xylitol metabolism The chemical reactions and pathways involving L-xylitol, a five-carbon sugar alcohol derived from xylose by reduction of the carbonyl group. It is as sweet as sucrose and is used as a noncariogenic sweetner and as a sugar substitute in diabetic diets. GO:0099106 ion channel regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0099106 Modulates the activity of a channel via direct interaction with it. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. GO:0075114 suppression by symbiont of host transmembrane receptor-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075114 negative regulation by symbiont of host transmembrane receptor-mediated signal transduction Any process in which the symbiont stops, prevents, or reduces the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0099107 ion channel regulator activity involved in G protein-coupled receptor signaling pathway biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0099107 ion channel regulator activity involved in G-protein coupled receptor signaling pathway Modulation of the activity of an ion channel via direct interaction with it as part of G protein-coupled receptor signaling. GO:0051165 2,5-dihydroxypyridine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051165 2,5-dihydroxypyridine metabolism|pyridine-2,5-diol metabolic process The chemical reactions and pathways involving 2,5-dihydroxypyridine. GO:0075148 obsolete positive regulation of signal transduction in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075148 positive regulation of symbiont signal transduction in response to host OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075149 obsolete negative regulation of signal transduction in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075149 negative regulation of symbiont signal transduction in response to host OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051179 localization biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0051179 establishment and maintenance of cellular component location|establishment and maintenance of substrate location|establishment and maintenance of localization|single-organism localization|localisation|single organism localization|establishment and maintenance of substance location|establishment and maintenance of position Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation. GO:0110078 TTT complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0110078 IntAct:EBI-16631004 Triple T complex|TELO2-TTI1-TTI2|Tel2-Tti1-Tti2 A protein complex responsible for the stabilisation of protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex can also be found as part of the ASTRA complex (GO:0070209). GO:0110079 regulation of placenta blood vessel development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110079 Any process that modulates the frequency, rate or extent of placenta blood vessel development. GO:0110076 negative regulation of ferroptosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110076 Any process that stops, prevents, or reduces the frequency, rate or extent of ferroptosis. GO:0110077 vesicle-mediated intercellular transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110077 A cellular transport process in which transported substances are moved in extracellular vesicles between cells; transported substances are enclosed in the vesicle lumen or located in the extracellular vesicle membrane. GO:0110074 positive regulation of apical constriction involved in ventral furrow formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110074 Any process that activates or increases the frequency, rate or extent of apical constriction involved in ventral furrow formation. GO:2000962 positive regulation of cellooligosaccharide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000962 positive regulation of cellooligosaccharide metabolism Any process that activates or increases the frequency, rate or extent of cellooligosaccharide metabolic process. GO:1905590 fibronectin fibril organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905590 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a fibronectin fibril. GO:0110075 regulation of ferroptosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110075 Any process that modulates the frequency, rate or extent of ferroptosis. GO:1905591 regulation of optical nerve axon regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905591 Any process that modulates the frequency, rate or extent of optical nerve axon regeneration. GO:2000963 regulation of cellooligosaccharide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000963 regulation of cellooligosaccharide catabolism Any process that modulates the frequency, rate or extent of cellooligosaccharide catabolic process. GO:1905592 negative regulation of optical nerve axon regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905592 down regulation of optical nerve axon regeneration|downregulation of optical nerve axon regeneration|down-regulation of optical nerve axon regeneration|inhibition of optical nerve axon regeneration Any process that stops, prevents or reduces the frequency, rate or extent of optical nerve axon regeneration. GO:0110072 apical constriction involved in ventral furrow formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110072 The actin-mediated process that results in contraction of the apical end of a polarized columnar epithelial cell, contributing to formation of a ventral indentation (furrow) from the blastoderm epithelium, which is internalized to form a tube in the interior of the embryo, marking the start of gastrulation. GO:2000964 negative regulation of cellooligosaccharide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000964 negative regulation of cellooligosaccharide catabolism Any process that stops, prevents or reduces the frequency, rate or extent of cellooligosaccharide catabolic process. GO:0110073 regulation of apical constriction involved in ventral furrow formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110073 Any process that modulates the frequency, rate or extent of apical constriction involved in ventral furrow formation. GO:1905593 positive regulation of optical nerve axon regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905593 upregulation of optical nerve axon regeneration|up regulation of optical nerve axon regeneration|activation of optical nerve axon regeneration|up-regulation of optical nerve axon regeneration Any process that activates or increases the frequency, rate or extent of optical nerve axon regeneration. GO:2000965 positive regulation of cellooligosaccharide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000965 positive regulation of cellooligosaccharide catabolism Any process that activates or increases the frequency, rate or extent of cellooligosaccharide catabolic process. GO:1905594 resveratrol binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1905594 Interacting selectively and non-covalently with resveratrol. GO:0110070 cellularization cleavage furrow biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0110070 A plasma membrane invagination at the site of separation of a multi-nucleate cell or syncytium into individual cells. GO:2000966 regulation of cell wall polysaccharide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000966 regulation of cell wall polysaccharide breakdown Any process that modulates the frequency, rate or extent of cell wall polysaccharide catabolic process. GO:1905595 regulation of low-density lipoprotein particle receptor binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905595 regulation of LDL receptor binding|regulation of low-density lipoprotein receptor binding Any process that modulates the frequency, rate or extent of low-density lipoprotein particle receptor binding. GO:2000967 negative regulation of cell wall polysaccharide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000967 negative regulation of cell wall polysaccharide breakdown Any process that stops, prevents or reduces the frequency, rate or extent of cell wall polysaccharide catabolic process. GO:0110071 cellularization cleavage furrow invagination front biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0110071 The base of the cellularization invagination or cleavage furrow most distal to the original multi-nucleate cell or syncytium plasma membrane. GO:1905596 negative regulation of low-density lipoprotein particle receptor binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905596 inhibition of low-density lipoprotein particle receptor binding|down-regulation of LDL receptor binding|negative regulation of LDL receptor binding|negative regulation of low-density lipoprotein receptor binding|down-regulation of low-density lipoprotein receptor binding|downregulation of LDL receptor binding|down regulation of low-density lipoprotein particle receptor binding|downregulation of low-density lipoprotein receptor binding|down regulation of LDL receptor binding|inhibition of LDL receptor binding|down regulation of low-density lipoprotein receptor binding|downregulation of low-density lipoprotein particle receptor binding|inhibition of low-density lipoprotein receptor binding|down-regulation of low-density lipoprotein particle receptor binding Any process that stops, prevents or reduces the frequency, rate or extent of low-density lipoprotein particle receptor binding. GO:2000968 positive regulation of cell wall polysaccharide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000968 positive regulation of cell wall polysaccharide breakdown Any process that activates or increases the frequency, rate or extent of cell wall polysaccharide catabolic process. GO:1905597 positive regulation of low-density lipoprotein particle receptor binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905597 activation of low-density lipoprotein receptor binding|up-regulation of low-density lipoprotein receptor binding|up-regulation of low-density lipoprotein particle receptor binding|positive regulation of LDL receptor binding|up regulation of LDL receptor binding|positive regulation of low-density lipoprotein receptor binding|up regulation of low-density lipoprotein receptor binding|upregulation of low-density lipoprotein particle receptor binding|upregulation of LDL receptor binding|upregulation of low-density lipoprotein receptor binding|up regulation of low-density lipoprotein particle receptor binding|activation of low-density lipoprotein particle receptor binding|activation of LDL receptor binding|up-regulation of LDL receptor binding Any process that activates or increases the frequency, rate or extent of low-density lipoprotein particle receptor binding. GO:2000969 positive regulation of AMPA receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity Any process that activates or increases the frequency, rate or extent of AMPA selective glutamate receptor activity. GO:1905587 positive regulation of outer hair cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905587 positive regulation of cochlear outer hair cell apoptotic process|up regulation of cochlear outer hair cell apoptotic process|upregulation of outer hair cell apoptotic process|upregulation of cochlear outer hair cell apoptosis|up regulation of outer hair cell apoptosis|positive regulation of outer hair cell apoptosis|upregulation of cochlear outer hair cell apoptotic process|up regulation of outer hair cell apoptotic process|activation of outer hair cell apoptotic process|activation of outer hair cell apoptosis|up-regulation of cochlear outer hair cell apoptosis|up-regulation of outer hair cell apoptosis|activation of cochlear outer hair cell apoptosis|up-regulation of cochlear outer hair cell apoptotic process|activation of cochlear outer hair cell apoptotic process|up-regulation of outer hair cell apoptotic process|positive regulation of cochlear outer hair cell apoptosis|up regulation of cochlear outer hair cell apoptosis|upregulation of outer hair cell apoptosis Any process that activates or increases the frequency, rate or extent of outer hair cell apoptotic process. GO:1905588 plant-type cell wall modification involved in stomatal movement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905588 cellulose and pectin-containing cell wall modification involved in stomatal movement Any plant-type cell wall modification that is involved in stomatal movement. GO:1905589 positive regulation of L-arginine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905589 positive regulation of L-arginine uptake|activation of L-arginine uptake|up-regulation of L-arginine import into cell|up-regulation of L-arginine import|up-regulation of L-arginine uptake|positive regulation of L-arginine import into cell|activation of L-arginine import across plasma membrane|upregulation of L-arginine import into cell|upregulation of L-arginine import|upregulation of L-arginine uptake|positive regulation of L-arginine import|up regulation of L-arginine import|activation of L-arginine import into cell|activation of L-arginine import|up regulation of L-arginine uptake Any process that activates or increases the frequency, rate or extent of L-arginine import across plasma membrane. CHEBI:16799 16alpha-hydroxy steroid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16799 GO:0051170 import into nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051170 single organism nuclear import|single-organism nuclear import|nuclear import|substance nuclear import The directed movement of substances into the nucleus. GO:2000960 regulation of cellooligosaccharide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000960 regulation of cellooligosaccharide metabolism Any process that modulates the frequency, rate or extent of cellooligosaccharide metabolic process. CHEBI:16797 1-methylnicotinamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16797 GO:2000961 negative regulation of cellooligosaccharide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000961 negative regulation of cellooligosaccharide metabolism Any process that stops, prevents or reduces the frequency, rate or extent of cellooligosaccharide metabolic process. CHEBI:41721 L-cysteine-S-dioxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_41721 GO:0051173 positive regulation of nitrogen compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051173 upregulation of nitrogen metabolic process|stimulation of nitrogen metabolic process|up-regulation of nitrogen metabolic process|activation of nitrogen metabolic process|positive regulation of nitrogen metabolic process|up regulation of nitrogen metabolic process|positive regulation of nitrogen metabolism Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds. CHEBI:16795 L-threo-3-phenylserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16795 GO:0075140 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075140 GO:0075141 obsolete symbiont tolerance to host environment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075141 maintenance of symbiont tolerance to host pH environment|maintenance of symbiont tolerance to host redox environment|maintenance of symbiont tolerance to host oxygen tension environment|maintenance of symbiont tolerance to host environment|maintenance of symbiont tolerance to host iron concentration|maintenance of symbiont tolerance to host osmotic environment OBSOLETE. Any process that contributes to the maintenance of a physiologic state in which the symbiont immune system does not react destructively against the components of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051174 regulation of phosphorus metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051174 regulation of phosphorus metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus. CHEBI:16796 melatonin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16796 GO:0075142 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075142 GO:0051171 regulation of nitrogen compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051171 regulation of nitrogen metabolism|regulation of nitrogen metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds. CHEBI:16793 mercury(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16793 GO:0051172 negative regulation of nitrogen compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051172 negative regulation of nitrogen metabolic process|down-regulation of nitrogen metabolic process|downregulation of nitrogen metabolic process|negative regulation of nitrogen metabolism|down regulation of nitrogen metabolic process|inhibition of nitrogen metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds. GO:0075143 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075143 CHEBI:16794 scopolamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16794 GO:0051177 meiotic sister chromatid cohesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051177 The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis. GO:0075144 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075144 GO:0090741 pigment granule membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090741 Any membrane that is part of a pigment granule. CHEBI:16791 vinorine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16791 GO:0051178 meiotic chromosome decondensation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051178 The cell cycle process in which chromosome structure is altered from the condensed form held during meiosis to the relaxed dispersed form held in resting cells. GO:0075145 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075145 CHEBI:16792 oxidized Photinus luciferin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16792 GO:0051175 negative regulation of sulfur metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051175 inhibition of sulfur metabolic process|negative regulation of sulphur metabolism|negative regulation of sulphur metabolic process|down-regulation of sulfur metabolic process|negative regulation of sulfur metabolism|downregulation of sulfur metabolic process|down regulation of sulfur metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur. GO:0075146 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075146 UBERON:0008367 breast epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008367 An epithelium that is part of a breast. GO:0051176 positive regulation of sulfur metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051176 upregulation of sulfur metabolic process|positive regulation of sulphur metabolic process|positive regulation of sulphur metabolism|stimulation of sulfur metabolic process|up-regulation of sulfur metabolic process|activation of sulfur metabolic process|positive regulation of sulfur metabolism|up regulation of sulfur metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur. GO:0075147 obsolete regulation of signal transduction in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075147 regulation of symbiont signal transduction in response to host OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0090740 integral component of pigment granule membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090740 The component of the pigment granule membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. NCBITaxon:1286322 Leishmaniinae organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_1286322 CHEBI:16790 15,16-dihydrobiliverdin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16790 GO:0075137 response to host redox environment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075137 response of symbiont to host redox environment Any process that results in a change in state or activity of the symbiont organism or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the redox environment in host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075138 response to host oxygen tension environment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075138 response of symbiont to host oxygen tension environment Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting oxygen tension in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075139 response to host iron concentration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075139 response of symbiont to host iron concentration Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting iron concentration in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0110089 regulation of hippocampal neuron apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110089 Any process that modulates the occurrence or rate of cell death by apoptotic process in hippocampal neurons. GO:0110087 suppression by virus of host protease activator activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110087 Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host protease activator activity. GO:0110088 hippocampal neuron apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110088 Any apoptotic process that occurs in a hippocampal neuron. GO:2000973 regulation of pro-B cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000973 regulation of pro-B lymphocyte differentiation|regulation of pro-B cell development Any process that modulates the frequency, rate or extent of pro-B cell differentiation. GO:0110085 mitotic actomyosin contractile ring biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0110085 A cytoskeletal structure composed of actin filaments, myosin, and myosin-associated proteins that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the mitotic spindle, i.e. the cell division plane. Ring contraction is associated with centripetal growth of the membrane that divides the cytoplasm of the two future daughter cells. In animal cells, the mitotic contractile ring is located inside the plasma membrane at the location of the cleavage furrow. In budding fungal cells, e.g. mitotic S. cerevisiae cells, the mitotic contractile ring forms beneath the plasma membrane at the mother-bud neck before mitosis. GO:0110086 meiotic actomyosin contractile ring biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0110086 A cytoskeletal structure composed of actin filaments, myosin, and myosin-associated proteins that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the meiotic spindle, i.e. the cell division plane. Ring contraction is associated with centripetal growth of the membrane that divides the cytoplasm of the two future daughter cells. In animal cells, the meiotic contractile ring is located inside the plasma membrane at the location of the cleavage furrow. In fungal cells, the meiotic contractile ring forms beneath the plasma membrane of the prospore envelope in preparation for completing cytokinesis. GO:2000974 negative regulation of pro-B cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000974 negative regulation of pro-B cell development|negative regulation of pro-B lymphocyte differentiation Any process that stops, prevents or reduces the frequency, rate or extent of pro-B cell differentiation. GO:0110083 positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110083 Any process that activates or increases the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly. GO:2000975 positive regulation of pro-B cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000975 positive regulation of pro-B cell development|positive regulation of pro-B lymphocyte differentiation Any process that activates or increases the frequency, rate or extent of pro-B cell differentiation. GO:2000976 obsolete regulation of transcription from RNA polymerase II promoter involved in detection of glucose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000976 regulation of transcription from RNA polymerase II promoter, global involved in glucose perception|regulation of global transcription from Pol II promoter involved in glucose sensing|regulation of global transcription from Pol II promoter involved in glucose perception|regulation of transcription from RNA polymerase II promoter, global involved in glucose sensing|regulation of transcription from RNA polymerase II promoter involved in glucose perception|regulation of global transcription from Pol II promoter involved in glucose detection|regulation of gene-specific transcription from RNA polymerase II promoter involved in detection of glucose|regulation of transcription from Pol II promoter involved in glucose perception|regulation of transcription from RNA polymerase II promoter, global involved in glucose detection|global transcription regulation from Pol II promoter involved in detection of glucose|global transcription regulation from Pol II promoter involved in glucose sensing|regulation of gene-specific transcription from RNA polymerase II promoter involved in glucose sensing|regulation of gene-specific transcription from RNA polymerase II promoter involved in glucose perception|global transcription regulation from Pol II promoter involved in glucose detection|global transcription regulation from Pol II promoter involved in glucose perception|regulation of transcription from RNA polymerase II promoter, global involved in detection of glucose|regulation of gene-specific transcription from RNA polymerase II promoter involved in glucose detection|regulation of global transcription from Pol II promoter involved in detection of glucose|regulation of transcription from Pol II promoter involved in glucose sensing|regulation of transcription from Pol II promoter involved in glucose detection|regulation of transcription from RNA polymerase II promoter involved in glucose sensing|regulation of transcription from RNA polymerase II promoter involved in glucose detection|regulation of transcription from Pol II promoter involved in detection of glucose OBSOLETE. Any regulation of transcription from RNA polymerase II promoter that is involved in detection of glucose. GO:0110084 negative regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110084 Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly. GO:0110081 negative regulation of placenta blood vessel development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110081 Any process that stops, prevents or reduces the frequency, rate or extent of placenta blood vessel development. GO:2000977 regulation of forebrain neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000977 Any process that modulates the frequency, rate or extent of forebrain neuron differentiation. GO:2000978 negative regulation of forebrain neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000978 Any process that stops, prevents or reduces the frequency, rate or extent of forebrain neuron differentiation. GO:0110082 regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110082 Any process that modulates the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly. GO:2000979 positive regulation of forebrain neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000979 Any process that activates or increases the frequency, rate or extent of forebrain neuron differentiation. GO:0110080 positive regulation of placenta blood vessel development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110080 Any process that activates or increases the frequency, rate or extent of placenta blood vessel development. GO:1905598 negative regulation of low-density lipoprotein receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905598 inhibition of LDLR activity|down-regulation of low-density lipoprotein receptor activity|down-regulation of LDL receptor|negative regulation of LDL receptor|inhibition of low-density lipoprotein receptor activity|down regulation of LDLR activity|downregulation of LDL receptor|downregulation of LDLR activity|down regulation of LDL receptor|down regulation of low-density lipoprotein receptor activity|inhibition of LDL receptor|downregulation of low-density lipoprotein receptor activity|negative regulation of LDLR activity|down-regulation of LDLR activity Any process that stops, prevents or reduces the frequency, rate or extent of low-density lipoprotein receptor activity. GO:1905599 positive regulation of low-density lipoprotein receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905599 up regulation of low-density lipoprotein receptor activity|activation of low-density lipoprotein receptor activity|up-regulation of LDL receptor|activation of LDL receptor|up-regulation of LDLR activity|up-regulation of low-density lipoprotein receptor activity|upregulation of LDLR activity|positive regulation of LDL receptor|up regulation of LDL receptor|upregulation of low-density lipoprotein receptor activity|up regulation of LDLR activity|activation of LDLR activity|positive regulation of LDLR activity|upregulation of LDL receptor Any process that activates or increases the frequency, rate or extent of low-density lipoprotein receptor activity. GO:0051180 vitamin transport biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0051180 vitamin or cofactor transport The directed movement of vitamins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. CHEBI:16788 CMP-N-acyl-beta-neuraminic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16788 GO:0051181 obsolete cofactor transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051181 vitamin or cofactor transport OBSOLETE. The directed movement of a cofactor into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A cofactor is a substance that is required for the activity of an enzyme or other protein. CHEBI:16789 aldehydo-D-lyxose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16789 GO:2000970 regulation of detection of glucose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000970 regulation of glucose perception|regulation of glucose sensing|regulation of glucose detection Any process that modulates the frequency, rate or extent of detection of glucose. GO:2000971 negative regulation of detection of glucose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000971 negative regulation of glucose perception|negative regulation of glucose sensing|negative regulation of glucose detection Any process that stops, prevents or reduces the frequency, rate or extent of detection of glucose. CHEBI:16786 vestitone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16786 GO:2000972 positive regulation of detection of glucose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000972 positive regulation of glucose perception|positive regulation of glucose sensing|positive regulation of glucose detection Any process that activates or increases the frequency, rate or extent of detection of glucose. CHEBI:16787 1-phospho-alpha-D-glucuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16787 CHEBI:41710 S-hydroxy-L-cysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_41710 GO:0051184 obsolete cofactor transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051184 cofactor transporter activity|vitamin or cofactor transporter activity OBSOLETE. Enables the transfer of a cofactor from one side of a membrane to the other. A cofactor is a substance that is required for the activity of an enzyme or other protein. CHEBI:16784 6beta-hydroxy-17beta-estradiol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16784 GO:0075130 modulation by symbiont of host protein kinase-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075130 Any process in which the symbiont modulates the frequency, rate or extent of protein kinase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051185 obsolete coenzyme transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051185 coenzyme transporter activity OBSOLETE. Enables the transfer of a coenzyme from one side of a membrane to the other. A coenzyme is any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed. CHEBI:16785 diisopropyl hydrogen phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16785 GO:0051182 obsolete coenzyme transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051182 OBSOLETE. The directed movement of a coenzyme into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A coenzyme is any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed. GO:0075131 induction by symbiont of host protein kinase-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075131 positive regulation by symbiont of host protein kinase-mediated signal transduction Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of protein kinase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:16782 (S)-2-hydroxyglutarate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16782 GO:0075132 suppression by symbiont of host protein kinase-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075132 negative regulation by symbiont of host protein kinase-mediated signal transduction Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of protein kinase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051183 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051183 CHEBI:16783 1D-myo-inositol 1,3,4,5-tetrakisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16783 CHEBI:16780 N-(6-aminohexanoyl)-6-aminohexanoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16780 GO:0051188 obsolete cofactor biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051188 cofactor anabolism|cofactor biosynthesis|cofactor synthesis|cofactor formation OBSOLETE. The chemical reactions and pathways resulting in the formation of a cofactor, a substance that is required for the activity of an enzyme or other protein. GO:0075133 modulation by symbiont of host calcium or calmodulin-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075133 modulation by symbiont of host Ca++ or calmodulin-mediated signal transduction Any process in which the symbiont modulates the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051189 prosthetic group metabolic process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0051189 coenzyme and prosthetic group metabolic process|prosthetic group metabolism|coenzyme and prosthetic group metabolism The chemical reactions and pathways involving a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein. GO:0075134 induction by symbiont of host calcium or calmodulin-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075134 positive regulation by symbiont of host calcium or calmodulin-mediated signal transduction|positive regulation by symbiont of host Ca++ or calmodulin-mediated signal transduction Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051186 obsolete cofactor metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051186 cofactor metabolism OBSOLETE. The chemical reactions and pathways involving a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate. GO:0075135 suppression by symbiont of host calcium or calmodulin-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075135 negative regulation by symbiont of host calcium or calmodulin-mediated signal transduction|negative regulation by symbiont of host Ca++ or calmodulin-mediated signal transduction Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051187 obsolete cofactor catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051187 cofactor catabolism|cofactor degradation|cofactor breakdown OBSOLETE. The chemical reactions and pathways resulting in the breakdown of a cofactor, a substance that is required for the activity of an enzyme or other protein. GO:0075136 response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075136 response of symbiont to host Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0002104 endonucleolytic cleaveage between 4.5S rRNA and 5S rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002104 Endonucleolytic cleavage between the 5S rRNA and the 4.5S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript. GO:0002105 endonucleolytic cleaveage between LSU-rRNA and 4.5S rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002105 Endonucleolytic cleavage between the LSU-rRNA and the 4.5S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript. GO:0002106 endonucleolytic cleaveage between SSU-rRNA and LSU-rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002106 Endonucleolytic cleavages between the SSU-rRNA and the LSU-rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. These cleavages liberate tRNAs from the polycistronic transcript as well as separating the SSU and LSU containing transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript. GO:0002107 generation of mature 3'-end of 5S rRNA generated by RNA polymerase III biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002107 The removal of extra uridine residues from the 3' end of a 5S pre-rRNA generated by transcription by RNA polymerase III to generate the mature 3'-end. GO:0002100 tRNA wobble adenosine to inosine editing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002100 The process in which an adenosine in position 34 of a tRNA is post-transcriptionally converted to inosine. GO:0002101 tRNA wobble cytosine modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002101 The process in which a cytosine in position 34 of a tRNA is post-transcriptionally modified. GO:0002102 podosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0002102 Wikipedia:Podosome An actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell, contain an F-actin-rich core surrounded by a ring structure containing proteins such as vinculin and talin, and have a diameter of 0.5 mm. GO:0002103 endonucleolytic cleavage of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002103 Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with four genes, in this order, are produced in the chloroplasts of vascular plants. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript. GO:0016749 N-succinyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016749 Catalysis of the transfer of a succinyl group to a nitrogen atom on the acceptor molecule. GO:0016745 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016745 GO:0016746 transferase activity, transferring acyl groups biolink:MolecularActivity go-plus goslim_chembl|goslim_drosophila|goslim_generic http://purl.obolibrary.org/obo/GO_0016746 Reactome:R-HSA-6792572|Reactome:R-HSA-193491|Reactome:R-HSA-192312|Reactome:R-HSA-159431|Reactome:R-HSA-8858298|EC:2.3.-.- acyltransferase activity Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor). GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016747 EC:2.3.1.- transferase activity, transferring groups other than amino-acyl groups Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor). CHEBI:51060 hormone agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51060 GO:0016748 succinyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016748 Catalysis of the transfer of a succinyl (3-carboxypropanoyl) group to an acceptor molecule. CHEBI:51061 hormone receptor modulator biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51061 GO:0016741 transferase activity, transferring one-carbon groups biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016741 EC:2.1.-.- Catalysis of the transfer of a one-carbon group from one compound (donor) to another (acceptor). GO:0016742 hydroxymethyl-, formyl- and related transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016742 EC:2.1.2.- Catalysis of the transfer of a hydroxymethyl- or formyl group from one compound (donor) to another (acceptor). GO:0016743 carboxyl- or carbamoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016743 EC:2.1.3.- carboxyl- and carbamoyltransferase activity Catalysis of the transfer of a carboxyl- or carbamoyl group from one compound (donor) to another (acceptor). GO:0016744 transferase activity, transferring aldehyde or ketonic groups biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016744 EC:2.2.1.-|EC:2.2.-.- transketolase or transaldolase activity Catalysis of the transfer of an aldehyde or ketonic group from one compound (donor) to another (acceptor). CHEBI:90675 ribonucleotide residue(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90675 CHEBI:75034 1-stearoyl-2-oleoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75034 CHEBI:90676 2'-O-methylribonucleotide(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90676 CHEBI:75031 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphoserine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75031 GO:0016740 transferase activity biolink:MolecularActivity go-plus goslim_chembl|goslim_mouse|goslim_yeast|goslim_candida|goslim_plant|goslim_pir|goslim_aspergillus|goslim_metagenomics http://purl.obolibrary.org/obo/GO_0016740 Reactome:R-HSA-8868783|EC:2.-.-.-|Reactome:R-HSA-1483089|Reactome:R-HSA-1483186|Reactome:R-HSA-5668414 Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. CHEBI:75032 1-palmitoyl-2-arachidonoyl-sn-glycero3-phosphoserine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75032 CHEBI:51069 organic halide salt biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51069 GO:0002108 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002108 Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 5S rRNA in that order from 5' to 3' along the primary transcript. GO:0002109 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002109 Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 5S rRNA in that order from 5' to 3' along the primary transcript. CHEBI:75038 1-stearoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75038 CHEBI:75036 1-stearoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75036 GO:0002115 store-operated calcium entry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002115 store-operated calcium import|calcium ion import|capacitative calcium entry|SOCE A calcium ion entry mechanism in the plasma membrane activated by the depletion of calcium ion from the internal calcium ion store in the endoplasmic reticulum. GO:0002116 semaphorin receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0002116 plexin-neurophilin complex A stable binary complex of a neurophilin and a plexin, together forming a functional semaphorin receptor. GO:0002117 amphibian larval development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002117 The process whose specific outcome is the progression of the amphibian larva over time, from its formation to the mature structure. Amphibian larvae, sometimes called pollywogs or tadpoles, hatch from eggs and begin to grow limbs and other adult physical features at various times, depending on the species, before they metamorphose into the adult form. GO:0002118 aggressive behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002118 Wikipedia:Aggression aggression A behavioral interaction between organisms in which one organism has the intention of inflicting physical damage on another individual. GO:0002111 BRCA2-BRAF35 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0002111 A heterodimeric complex of BRCA2 and BRAF35 (BRCA2-associated factor 35). The BRCA2-BRAF35 complex is often associated with condensed chromatin during mitosis. GO:0002112 interleukin-33 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0002112 interleukin-33 receptor ligand|IL-33 Interacting selectively and non-covalently with the interleukin-33 receptor. GO:0002113 interleukin-33 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0002113 IL-33 binding Interacting selectively and non-covalently with interleukin-33. GO:0002114 interleukin-33 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0002114 IL-33R|IL-33 receptor activity Combining with interleukin-33 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0002110 cotranscriptional mitochondrial rRNA nucleotide insertion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002110 The insertion of one or two non-coded nucleotides during the transcription of a mitochondrial rRNA. Such additions are known to occur in myxomycetes such as Physarum, Didymium, and Stemonitis. GO:0016756 glutathione gamma-glutamylcysteinyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016756 MetaCyc:2.3.2.15-RXN|EC:2.3.2.15|RHEA:17917 gamma-glutamylcysteine dipeptidyl transpeptidase activity|glutathione:poly(4-glutamyl-cysteinyl)glycine 4-glutamylcysteinyltransferase activity|phytochelatin synthase activity Catalysis of the reaction: glutathione + Glu(-Cys)(n)-Gly = Gly + Glu(-Cys)(n+1)-Gly. GO:0016757 transferase activity, transferring glycosyl groups biolink:MolecularActivity go-plus goslim_drosophila|goslim_generic|goslim_chembl|goslim_yeast http://purl.obolibrary.org/obo/GO_0016757 Reactome:R-HSA-5173005|Reactome:R-HSA-6785565|EC:2.4.-.- transferase activity, transferring other glycosyl groups|transglycosidase activity|glycosyltransferase activity|transglycosylase activity Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor). GO:0016758 transferase activity, transferring hexosyl groups biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016758 EC:2.4.1.- hexosyltransferase activity Catalysis of the transfer of a hexosyl group from one compound (donor) to another (acceptor). GO:0016759 cellulose synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016759 cellulose synthetase activity Catalysis of the reaction: nucleoside-disphosphate-glucose + ((1,4)-beta-D-glucosyl)(n) = nucleoside-disphosphate + ((1,4)-beta-D-glucosyl)(n+1). GO:0016752 sinapoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016752 Catalysis of the transfer of a sinapoyl group to an acceptor molecule. GO:0016753 O-sinapoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016753 Catalysis of the transfer of a sinapoyl group to an oxygen atom on the acceptor molecule. GO:0016754 sinapoylglucose-malate O-sinapoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016754 MetaCyc:2.3.1.92-RXN|RHEA:12625|KEGG_REACTION:R03323|EC:2.3.1.92 sinapoylglucose:malate sinapoyltransferase activity|1-O-sinapoyl-beta-D-glucose:(S)-malate O-sinapoyltransferase activity|1-sinapoylglucose-L-malate sinapoyltransferase activity Catalysis of the reaction: (S)-malate + 1-O-sinapoyl-beta-D-glucose = D-glucose + sinapoyl (S)-malate. GO:0016755 transferase activity, transferring amino-acyl groups biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016755 EC:2.3.2.- aminoacyltransferase activity Catalysis of the transfer of an amino-acyl group from one compound (donor) to another (acceptor). GO:0016750 O-succinyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016750 Catalysis of the transfer of a succinyl group to an oxygen atom on the acceptor molecule. CHEBI:51057 3-phenylpropionate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_51057 GO:0016751 S-succinyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016751 Catalysis of the transfer of a succinyl group to a sulfur atom on the acceptor molecule. GO:0002119 nematode larval development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002119 The process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew. CHEBI:51051 N-(3-acetamidopropyl)-4-aminobutanal biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51051 GO:0016727 oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016727 EC:1.17.3.- Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces an oxygen molecule. GO:0016728 oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016728 EC:1.17.4.- oxidoreductase activity, acting on CH or CH2 groups, disulphide as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a disulfide group. GO:0016729 obsolete oxidoreductase activity, acting on CH2 groups, other acceptors biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016729 oxidoreductase activity, acting on CH2 groups, other acceptors OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces an acceptor other than disulfide, NAD, NADP or oxygen. CHEBI:26087 photosynthetic electron-transport chain inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26087 GO:0016723 oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016723 Reactome:R-HSA-917811|EC:1.16.1.- oxidoreductase activity, reducing metal ions, NAD or NADP as acceptor|oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor Catalysis of an oxidation-reduction in which the metal ion is reduced and NAD+ or NADP+ acts as an electron acceptor. GO:0016724 oxidoreductase activity, acting on metal ions, oxygen as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016724 EC:1.16.3.- oxidoreductase activity, oxidizing metal ions, oxygen as acceptor Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered and oxygen acts as an electron acceptor. CHEBI:26092 phthalate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26092 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016725 EC:1.17.-.- oxidoreductase activity, acting on CH or CH2 groups, other acceptors Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. GO:0016726 oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016726 EC:1.17.1.- Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces NAD+ or NADP. CHEBI:26094 benzenedicarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26094 CHEBI:75051 2-amino-5-chlorophenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75051 GO:0016720 delta12-fatty acid dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016720 MetaCyc:1.14.99.33-RXN|RHEA:23456|KEGG_REACTION:R05740|EC:1.14.99.33 linoleate, hydrogen-donor:oxygen oxidoreductase (Delta12-unsaturating)|D12-fatty acid dehydrogenase activity|linoleate delta-12-fatty acid acetylenase (desaturase) activity|delta12 fatty acid acetylenase activity|delta-12 fatty acid acetylenase activity|crepenynate synthase activity|linoleate delta12-fatty acid acetylenase (desaturase) Catalysis of the reaction: AH(2) + linoleate + O(2) = A + crepenynate + 2 H(2)O. PR:000003425 Hsp70 family chaperone biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000003425 A protein that is a stand alone version of the Hsp70 protein (Pfam:PF00012) domain, which comprises two major regions: an N-terminal ATP-binding domain and a C-terminal substrate-binding domain. CHEBI:75052 3-dehydro-D-glucose-6-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75052 GO:0016721 oxidoreductase activity, acting on superoxide radicals as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016721 EC:1.15.-.- Catalysis of an oxidation-reduction (redox) reaction in which a superoxide radical (O2- or O2.-) acts as a hydrogen or electron acceptor. CHEBI:75050 chromogenic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75050 GO:0016722 oxidoreductase activity, acting on metal ions biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016722 Reactome:R-HSA-917805|EC:1.16.-.- oxidoreductase activity, reducing metal ions|oxidoreductase activity, oxidizing metal ions Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered. CHEBI:90696 thromboxane B2(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90696 CHEBI:90697 11-oxo-ETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90697 CHEBI:75057 2-amino-5-chloro-cis,cis-muconate 6-semialdehyde zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75057 CHEBI:90694 12(S)-HHTrE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90694 CHEBI:90680 12(S)-HETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90680 CHEBI:51039 dopamine uptake inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51039 GO:0016738 oxidoreductase activity, acting on reduced flavodoxin as donor, dinitrogen as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016738 EC:1.19.6.- Catalysis of an oxidation-reduction (redox) reaction in which reduced flavodoxin acts as a hydrogen or electron donor and reduces dinitrogen. GO:0016739 obsolete oxidoreductase activity, acting on other substrates biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016739 oxidoreductase activity, acting on other substrates OBSOLETE. A grouping term for oxidoreductase that cannot be more accurately categorized. GO:0016734 obsolete molybdenum-iron nitrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016734 molybdenum-iron nitrogenase activity OBSOLETE. Catalysis of the reaction: 8 reduced ferredoxin + 8 H+ + N2 + 16 ATP = 8 oxidized ferredoxin + 2 NH3 + 16 ADP + 16 phosphate. GO:0016735 obsolete vanadium-iron nitrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016735 vanadium-iron nitrogenase activity OBSOLETE. Catalysis of the reaction: 8 reduced ferredoxin + 8 H+ + nitrogen + 16 ATP = 8 oxidized ferredoxin + 2 NH3 + 16 ADP + 16 phosphate. GO:0016736 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016736 GO:0016737 oxidoreductase activity, acting on reduced flavodoxin as donor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016737 EC:1.19.-.- Catalysis of an oxidation-reduction (redox) reaction in which reduced flavodoxin acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. GO:0016730 oxidoreductase activity, acting on iron-sulfur proteins as donors biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016730 EC:1.18.-.- oxidoreductase activity, acting on iron-sulphur proteins as donors Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. CHEBI:75062 1-myristoyl-2-palmitoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75062 GO:0016731 oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016731 EC:1.18.1.- Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces NAD or NADP. CHEBI:75063 1-acyl-2-arachidonoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75063 GO:0016732 oxidoreductase activity, acting on iron-sulfur proteins as donors, dinitrogen as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016732 EC:1.18.6.- Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces dinitrogen. GO:0016733 obsolete iron-iron nitrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016733 iron-iron nitrogenase activity OBSOLETE. Catalysis of the reaction: 8 reduced ferredoxin + 8 H+ + N2 + 16 ATP = 8 oxidized ferredoxin + 2 NH3 + 16 ADP + 16 phosphate. CHEBI:75061 trans-2-icosenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75061 CHEBI:75066 1-acyl-2-linoleoyl-sn-glycero-3-phosphoserine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75066 CHEBI:75067 1-acyl-2-arachidonoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75067 CHEBI:75064 trans-2-docosenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75064 CHEBI:90688 metformin(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90688 CHEBI:75065 1-acyl-2-arachidonoyl-sn-glycero-3-phosphoserine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75065 CHEBI:75068 trans-2-tetracosenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75068 CHEBI:51031 organic calcium salt biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51031 CHEBI:75069 1-acyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75069 CHEBI:51026 macrocycle biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51026 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016709 Reactome:R-HSA-2162187|EC:1.14.13.-|Reactome:R-HSA-2162194 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor. CHEBI:26066 phosphonate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26066 CHEBI:26069 phosphonic acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26069 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016705 EC:1.14.-.- oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, miscellaneous Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor. GO:0016706 2-oxoglutarate-dependent dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016706 Reactome:R-HSA-6783455|Reactome:R-HSA-1234164|EC:1.14.11.- 2-oxoglutarate dioxygenase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors Catalysis of the reaction: A + 2-oxoglutarate + O2 = B + succinate + CO2. This is an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and one atom of oxygen is incorporated into each donor. GO:0016707 gibberellin 3-beta-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016707 EC:1.14.11.15|RHEA:10104|MetaCyc:RXN1F-170 gibberellin 3beta-dioxygenase activity|(gibberrellin-20),2-oxoglutarate: oxygen oxidoreductase (3beta-hydroxylating)|gibberellin 3beta-hydroxylase activity|(gibberellin-20),2-oxoglutarate:oxygen oxidoreductase (3beta-hydroxylating)|gibberellin 3-beta-hydroxylase activity Catalysis of the reaction: a gibberellin + 2-oxoglutarate + O2 = a 3-beta-hydroxy-gibberellin + succinate + CO2. GO:0016708 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016708 EC:1.14.12.- oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and two atoms of oxygen are incorporated into one donor. GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016701 EC:1.13.-.- oxygenase|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, miscellaneous Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and molecular oxygen is incorporated into a donor. GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016702 Reactome:R-HSA-2161917|Reactome:R-HSA-2161775|Reactome:R-HSA-5164399|Reactome:R-HSA-9020274|Reactome:R-HSA-2161907|Reactome:R-HSA-9026408|EC:1.13.11.-|Reactome:R-HSA-9018880|Reactome:R-HSA-9026918 Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and two oxygen atoms is incorporated into a donor. UBERON:0008425 mammary ridge biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008425 mammary line|milk line|mammary gland ridge|mammary fold A ridge of epidermal cells that will form the mammary placodes. CHEBI:75070 1-palmitoleoyl-sn-glycerol 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75070 GO:0016703 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016703 EC:1.13.12.- Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and one oxygen atom is incorporated into a donor. GO:0016704 obsolete oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, miscellaneous biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016704 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, miscellaneous OBSOLETE. A grouping term for oxidoreductases acting on single donors with incorporation of molecular oxygen that cannot be more accurated categorized. CHEBI:75074 1-(9Z)-octadecenoyl-2-(9Z)-hexadecenoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75074 UBERON:0008429 cervical vertebral foramen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008429 A vertebral foramen that is part of a cervical vertebra. GO:0016700 obsolete oxidoreductase activity, acting on hydrogen as donor, other acceptors biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016700 oxidoreductase activity, acting on hydrogen as donor, other acceptors OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which hydrogen is the electron donor and reduces an acceptor other than a cytochrome, an iron-sulfur protein, NAD, NADP or a quinone or similar compound. CHEBI:51022 1,3-dihydro-2H-imidazol-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_51022 CHEBI:75077 N(1)-methylpseudouridine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75077 CHEBI:75078 N(1)-methylpseudouridine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75078 CHEBI:75075 2,3-bis-O-phytanyl-sn-glycero-3-phospho-L-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75075 CHEBI:75076 1-oleoyl-2-lauroyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75076 CHEBI:75079 N(3)-methylcytidine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75079 CHEBI:26078 phosphoric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26078 CHEBI:26079 phosphoric acid derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26079 CHEBI:26073 phosphopantetheine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26073 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016716 EC:1.14.18.- Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and one atom of oxygen is incorporated into one donor. GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016717 EC:1.14.19.- Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced to two molecules of water. GO:0016718 obsolete oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, miscellaneous biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016718 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, miscellaneous OBSOLETE. A grouping term for oxidoreductases, acting on paired donors with incorporation or reduction of molecular oxygen, that cannot be more accurately categorized. GO:0016719 carotene 7,8-desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016719 RHEA:15701|MetaCyc:1.14.99.30-RXN|EC:1.3.5.6 carotene,hydrogen-donor:oxygen oxidoreductase activity|zeta-carotene desaturase activity Catalysis of the reaction: neurosporene + donor-H2 + O2 = lycopene + acceptor + 2 H2O. GO:0089700 protein kinase D signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0089700 PKD signal transduction|protein kinase D signal transduction|PKD signaling cascade|protein kinase D signalling cascade|protein kinase D signaling cascade A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase D, which occurs as a result of a single trigger reaction or compound. GO:0089701 U2AF complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0089701 U2AF|U2 accessory factor A heterodimeric protein complex consisting of conserved large and small U2AF subunits that contributes to spliceosomal RNA splicing by binding to consensus sequences at the 3' splice site. U2AF is required to stabilize the association of the U2 snRNP with the branch point. GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016712 Reactome:R-HSA-211966|UM-BBD_enzymeID:e0551|EC:1.14.14.- microsomal p450 activity|microsomal monooxygenase activity|substrate,reduced-flavoprotein:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)|flavoprotein monooxygenase activity|aryl-4-monooxygenase activity|xenobiotic monooxygenase activity|microsomal P-450|flavoprotein-linked monooxygenase activity|cytochrome P450 CYP19|cytochrome p450 activity|aryl hydrocarbon hydroxylase activity|unspecific monooxygenase activity Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced flavin or flavoprotein and one other donor, and one atom of oxygen is incorporated into one donor. GO:0089702 undecaprenyl-phosphate glucose phosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0089702 Catalysis of the reaction: UDP-glucose + ditrans,octacis-undecaprenyl phosphate = UMP + alpha-D-glucopyranosyl-diphospho-ditrans,octacis-undecaprenol. GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016713 EC:1.14.15.- oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulphur protein as one donor, and incorporation of one atom of oxygen Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced iron-sulfur protein and one other donor, and one atom of oxygen is incorporated into one donor. GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016714 EC:1.14.16.- Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced pteridine and one other donor, and one atom of oxygen is incorporated into one donor. GO:0089703 L-aspartate transmembrane export from vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0089703 The directed movement of L-aspartate out of the vacuole, across the vacuolar membrane. CHEBI:26082 phosphorus molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26082 GO:0089704 L-glutamate transmembrane export from vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0089704 The directed movement of L-glutamate out of the vacuole, across the vacuolar membrane. GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016715 EC:1.14.17.- Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced ascorbate and one other donor, and one atom of oxygen is incorporated into one donor. GO:0089705 protein localization to outer membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0089705 A process in which a protein is transported to, or maintained in, a specific location the cell outer membrane. GO:0089706 L-ornithine transmembrane export from vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0089706 The directed movement of L-ornithine out of the vacuole, across the vacuolar membrane. CHEBI:75085 N(4)-acetylcytidine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75085 GO:0016710 trans-cinnamate 4-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016710 RHEA:10608|EC:1.14.14.91|MetaCyc:TRANS-CINNAMATE-4-MONOOXYGENASE-RXN cinnamate 4-hydroxylase activity|oxygenase, cinnamate 4-mono-|cinnamic acid 4-monooxygenase activity|CA4H activity|trans-cinnamate,NADPH:oxygen oxidoreductase (4-hydroxylating)|hydroxylase, cinnamate 4-|cinnamic 4-hydroxylase activity|trans-cinnamic acid 4-hydroxylase activity|cinnamic acid p-hydroxylase activity|cinnamic acid 4-hydroxylase activity|t-cinnamic acid hydroxylase activity|cytochrome P450 cinnamate 4-hydroxylase activity|cinnamate 4-monooxygenase activity|cinnamate hydroxylase activity|trans-cinnamate 4-hydroxylase activity Catalysis of the reaction: trans-cinnamate + NADPH + H+ + O2 = 4-hydroxycinnamate + NADP+ + H2O. GO:0089707 L-lysine transmembrane export from vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0089707 The directed movement of L-lysine out of the vacuole, across the vacuolar membrane. GO:0016711 flavonoid 3'-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016711 RHEA:16337|MetaCyc:FLAVONOID-3-MONOOXYGENASE-RXN|EC:1.14.14.82 flavonoid 3-hydroxylase|flavonoid 3-monooxygenase|NADPH:flavonoid-3'-hydroxylase activity|flavonoid 3'-hydroxylase activity|flavonoid,NADPH:oxygen oxidoreductase (3'-hydroxylating) Catalysis of the reaction: a flavonoid + NADPH + H+ + O2 = 3'-hydroxyflavonoid + NADP+ + H2O. GO:0089708 L-histidine transmembrane export from vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0089708 The directed movement of L-histidine out of the vacuole, across the vacuolar membrane. CHEBI:75083 N(3)-methylcytidine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75083 GO:0089709 L-histidine transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0089709 The directed movement of L-histidine across a membrane. CHEBI:51013 beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51013 CHEBI:51014 (S)-styrene oxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_51014 CHEBI:51006 unsaturated fatty acyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51006 CHEBI:26044 phosphinic acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26044 CHEBI:26045 phosphite ion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26045 CHEBI:75091 aclacinomycin N biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75091 GO:1905500 obsolete heteroreceptor complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905500 heteroreceptor complex formation OBSOLETE. The aggregation, arrangement and bonding together of a set of components to form a heteroreceptor complex. UBERON:0008404 proximal tubular epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008404 epithelium of proximal renal tubule|proximal renal tubule epithelium|proximale tubular epithelium|proximal tubule epithelium|epithelium of proximal convoluted tubule The cells lining the proximal tubule are cuboidal epithelial cells with deep basal membrane invaginations that provide a large basal surface area. The long microvilli (the brush border) lining the tubule lumen, maximize luminal surface area and make these cells ideally suited for both reabsorptive and secretory functions. GO:1905501 obsolete heteroreceptor complex disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905501 OBSOLETE. The disaggregation of a heteroreceptor complex into its constituent components. GO:1905502 acetyl-CoA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1905502 acetyl-coenzyme A binding Interacting selectively and non-covalently with acetyl-CoA, an acyl-CoA having acetyl as its S-acetyl component. GO:1905503 regulation of motile cilium assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905503 regulation of motile primary cilia formation|regulation of nodal cilium formation|regulation of motile primary cilium formation|regulation of nodal cilium assembly|regulation of motile primary cilia assembly|regulation of motile primary cilium assembly Any process that modulates the frequency, rate or extent of motile cilium assembly. GO:1905504 negative regulation of motile cilium assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905504 downregulation of nodal cilium formation|down regulation of motile primary cilia formation|downregulation of motile primary cilium assembly|inhibition of motile primary cilium assembly|inhibition of nodal cilium assembly|down regulation of nodal cilium formation|down regulation of motile primary cilium assembly|negative regulation of motile primary cilium assembly|down regulation of motile primary cilium formation|inhibition of nodal cilium formation|down regulation of nodal cilium assembly|down regulation of motile primary cilia assembly|downregulation of motile primary cilium formation|downregulation of nodal cilium assembly|downregulation of motile primary cilia assembly|down-regulation of motile primary cilia formation|negative regulation of motile primary cilia formation|negative regulation of nodal cilium formation|negative regulation of motile primary cilium formation|down-regulation of motile primary cilium formation|down-regulation of nodal cilium formation|negative regulation of nodal cilium assembly|down-regulation of motile primary cilium assembly|down-regulation of nodal cilium assembly|inhibition of motile primary cilium formation|negative regulation of motile primary cilia assembly|down-regulation of motile primary cilia assembly|inhibition of motile primary cilia assembly|downregulation of motile primary cilia formation|inhibition of motile primary cilia formation Any process that stops, prevents or reduces the frequency, rate or extent of motile cilium assembly. CHEBI:75096 1-oleoyl-2-linoleoyl-sn-glycero-3-phospho-L-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75096 GO:1905505 positive regulation of motile cilium assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905505 up-regulation of motile primary cilium formation|up regulation of motile primary cilium assembly|up-regulation of nodal cilium assembly|up-regulation of motile primary cilia assembly|upregulation of motile primary cilia formation|upregulation of nodal cilium formation|upregulation of motile primary cilium formation|upregulation of motile primary cilium assembly|upregulation of nodal cilium assembly|activation of motile primary cilia formation|upregulation of motile primary cilia assembly|up-regulation of motile primary cilia formation|activation of motile primary cilium assembly|positive regulation of motile primary cilium assembly|activation of motile primary cilium formation|up-regulation of nodal cilium formation|up regulation of motile primary cilium formation|up-regulation of motile primary cilium assembly|up regulation of nodal cilium assembly|activation of motile primary cilia assembly|positive regulation of motile primary cilium formation|positive regulation of nodal cilium assembly|up regulation of motile primary cilia assembly|activation of nodal cilium formation|positive regulation of motile primary cilia assembly|positive regulation of motile primary cilia formation|activation of nodal cilium assembly|up regulation of motile primary cilia formation|positive regulation of nodal cilium formation|up regulation of nodal cilium formation Any process that activates or increases the frequency, rate or extent of motile cilium assembly. CHEBI:75093 aclacinomycin Y biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75093 UBERON:0008408 distal tubular epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008408 distal tubule epithelium An epithelium that is part of a distal tubule. GO:1905506 gerontoplast stroma biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1905506 Any plastid stroma that is part of a gerontoplast. CHEBI:41688 crystal violet biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_41688 GO:1905507 obsolete cytoplasmic sequestering of protein involved in mitotic G2 DNA damage checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905507 OBSOLETE. Any cytoplasmic sequestering of protein that is involved in mitotic G2 DNA damage checkpoint. CHEBI:75099 1-oleoyl-2-arachidonoyl-sn-glycero-3-phospho-L-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_75099 GO:1905508 protein localization to microtubule organizing center biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905508 protein localisation in microtubule organizing center|protein localisation to microtubule organizing center|protein localization in microtubule organizing center A process in which a protein is transported to, or maintained in, a location within a microtubule organizing center. GO:1905509 protein localization to interphase microtubule organizing center biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905509 protein localisation to interphase microtubule organizing center|protein localisation in interphase microtubule organizing center|protein localization in interphase microtubule organizing center A process in which a protein is transported to, or maintained in, a location within an interphase microtubule organizing center. GO:0051104 DNA-dependent DNA replication DNA ligation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051104 DNA ligation during DNA-dependent DNA replication|DNA ligation involved in DNA-dependent DNA replication The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, that contributes to DNA-dependent DNA replication. GO:0051105 regulation of DNA ligation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051105 Any process that modulates the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase. GO:0051102 DNA ligation involved in DNA recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051102 DNA ligation during DNA recombination The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, that contributes to DNA recombination. GO:0051103 DNA ligation involved in DNA repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051103 DNA ligation during DNA repair The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, that contributes to DNA repair. GO:0051108 carnitine-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051108 MetaCyc:DCARNCOALIG-RXN|RHEA:30543 crotonobetaine/carnitine-CoA ligase activity|carnitine synthetase activity Catalysis of the reaction: D-carnitine + CoA + ATP = AMP + diphosphate + D-carnitinyl-CoA. GO:0051109 crotonobetaine-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051109 MetaCyc:CROTCOALIG-RXN|RHEA:30079 crotonobetaine/carnitine-CoA ligase activity|crotonobetaine-CoA synthase activity Catalysis of the reaction: CoA + crotono-betaine + ATP = AMP + diphosphate + crotonobetainyl-CoA. GO:0051106 positive regulation of DNA ligation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051106 upregulation of DNA ligation|stimulation of DNA ligation|up-regulation of DNA ligation|activation of DNA ligation|up regulation of DNA ligation Any process that activates or increases the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase. GO:0051107 negative regulation of DNA ligation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051107 downregulation of DNA ligation|down regulation of DNA ligation|inhibition of DNA ligation|down-regulation of DNA ligation Any process that stops, prevents, or reduces the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase. CHEBI:41674 cyclohexane-1,2-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_41674 CHEBI:26057 phosphoglycosphingolipid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26057 CHEBI:26051 phosphoamino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26051 GO:1905520 positive regulation of presynaptic active zone assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905520 upregulation of pre-synaptic active zone component formation|activation of pre-synaptic active zone component assembly|up regulation of pre-synaptic active zone assembly|activation of pre-synaptic active zone assembly|upregulation of pre-synaptic active zone formation|positive regulation of pre-synaptic active zone assembly|up-regulation of pre-synaptic active zone component assembly|upregulation of presynaptic active zone formation|up-regulation of pre-synaptic active zone component formation|up regulation of presynaptic active zone assembly|activation of pre-synaptic active zone formation|up-regulation of pre-synaptic active zone formation|activation of pre-synaptic active zone component formation|upregulation of pre-synaptic active zone component assembly|up-regulation of pre-synaptic active zone assembly|up regulation of presynaptic active zone formation|activation of presynaptic active zone formation|positive regulation of presynaptic active zone formation|positive regulation of pre-synaptic active zone component formation|upregulation of presynaptic active zone assembly|up regulation of pre-synaptic active zone component formation|positive regulation of pre-synaptic active zone formation|upregulation of pre-synaptic active zone assembly|up regulation of pre-synaptic active zone component assembly|up regulation of pre-synaptic active zone formation|positive regulation of pre-synaptic active zone component assembly|up-regulation of presynaptic active zone formation|activation of presynaptic active zone assembly|up-regulation of presynaptic active zone assembly Any process that activates or increases the frequency, rate or extent of presynaptic active zone assembly. GO:1905510 negative regulation of myosin II filament assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905510 downregulation of myosin II polymerization|down regulation of myosin II polymerization|inhibition of myosin II filament assembly|inhibition of myosin II polymerization|down regulation of myosin II filament assembly|downregulation of myosin II filament assembly|down-regulation of myosin II polymerization|negative regulation of myosin II polymerization|down-regulation of myosin II filament assembly Any process that stops, prevents or reduces the frequency, rate or extent of myosin II filament assembly. GO:1905511 positive regulation of myosin II filament assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905511 up-regulation of myosin II filament assembly|upregulation of myosin II polymerization|upregulation of myosin II filament assembly|up-regulation of myosin II polymerization|activation of myosin II polymerization|up regulation of myosin II filament assembly|activation of myosin II filament assembly|positive regulation of myosin II polymerization|up regulation of myosin II polymerization Any process that activates or increases the frequency, rate or extent of myosin II filament assembly. GO:1905512 regulation of short-term synaptic potentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905512 regulation of synaptic facilitation Any process that modulates the frequency, rate or extent of short-term synaptic potentiation. GO:1905513 negative regulation of short-term synaptic potentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905513 downregulation of short-term synaptic potentiation|down regulation of short-term synaptic potentiation|inhibition of short-term synaptic potentiation|down regulation of synaptic facilitation|downregulation of synaptic facilitation|negative regulation of synaptic facilitation|down-regulation of synaptic facilitation|down-regulation of short-term synaptic potentiation|inhibition of synaptic facilitation Any process that stops, prevents or reduces the frequency, rate or extent of short-term synaptic potentiation. GO:1905514 positive regulation of short-term synaptic potentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905514 upregulation of synaptic facilitation|upregulation of short-term synaptic potentiation|up regulation of synaptic facilitation|activation of synaptic facilitation|positive regulation of synaptic facilitation|up-regulation of short-term synaptic potentiation|activation of short-term synaptic potentiation|up-regulation of synaptic facilitation|up regulation of short-term synaptic potentiation Any process that activates or increases the frequency, rate or extent of short-term synaptic potentiation. GO:1905515 non-motile cilium assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905515 non-motile cilium formation|immotile primary cilium assembly|nonmotile primary cilium assembly|sensory cilium assembly|nonmotile cilium formation|sensory cilium biogenesis|nonmotile cilium assembly|nonmotile primary cilia assembly The aggregation, arrangement and bonding together of a set of components to form a non-motile cilium. GO:1905516 positive regulation of fertilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905516 up-regulation of fertilization|up regulation of syngamy|activation of syngamy|positive regulation of syngamy|upregulation of fertilization|up-regulation of syngamy|up regulation of fertilization|activation of fertilization|upregulation of syngamy Any process that activates or increases the frequency, rate or extent of fertilization. GO:1905517 macrophage migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905517 The orderly movement of a macrophage from one site to another. GO:1905518 regulation of presynaptic active zone assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905518 regulation of presynaptic active zone formation|regulation of pre-synaptic active zone component assembly|regulation of pre-synaptic active zone component formation|regulation of pre-synaptic active zone assembly|regulation of pre-synaptic active zone formation Any process that modulates the frequency, rate or extent of presynaptic active zone assembly. GO:1905519 negative regulation of presynaptic active zone assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905519 down regulation of presynaptic active zone formation|inhibition of pre-synaptic active zone component assembly|downregulation of presynaptic active zone formation|inhibition of pre-synaptic active zone assembly|downregulation of presynaptic active zone assembly|down-regulation of pre-synaptic active zone component formation|negative regulation of pre-synaptic active zone component formation|down regulation of presynaptic active zone assembly|down regulation of pre-synaptic active zone component assembly|negative regulation of pre-synaptic active zone formation|inhibition of presynaptic active zone assembly|down-regulation of pre-synaptic active zone formation|negative regulation of presynaptic active zone formation|downregulation of pre-synaptic active zone component assembly|down-regulation of presynaptic active zone formation|downregulation of pre-synaptic active zone component formation|down regulation of pre-synaptic active zone assembly|inhibition of presynaptic active zone formation|downregulation of pre-synaptic active zone formation|down regulation of pre-synaptic active zone component formation|downregulation of pre-synaptic active zone assembly|negative regulation of pre-synaptic active zone component assembly|down-regulation of pre-synaptic active zone component assembly|down regulation of pre-synaptic active zone formation|inhibition of pre-synaptic active zone formation|inhibition of pre-synaptic active zone component formation|down-regulation of presynaptic active zone assembly|negative regulation of pre-synaptic active zone assembly|down-regulation of pre-synaptic active zone assembly Any process that stops, prevents or reduces the frequency, rate or extent of presynaptic active zone assembly. GO:0051100 negative regulation of binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051100 down-regulation of binding|inhibition of binding|down regulation of binding|downregulation of binding Any process that stops or reduces the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule. GO:0051101 regulation of DNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051101 Any process that modulates the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid). GO:0002188 translation reinitiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002188 A gene-specific translational control mechanism where the small ribosomal subunit remains attached to the mRNA following termination of translation, then resumes scanning on the same mRNA molecule and initiates again at a downstream start site. Reinitiation depends on de novo recruitment of the ternary complex that is required to recognize the next AUG codon. GO:0002189 ribose phosphate diphosphokinase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0002189 PRPP synthetase complex|phosphoribosylpyrophosphate synthetase complex A protein complex having ribose phosphate diphosphokinase activity. GO:0099098 microtubule polymerization based movement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099098 The movement of a cellular component as a result of microtubule polymerization. GO:0099099 G-protein gated ion channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0099099 An ion channel activity that is gated by binding of a G-protein beta-gamma dimer. GO:0099096 vestibular calyx terminal biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0099096 The giant, cup-shaped axon terminal of a vestibular afferent neuron, serving as a post-synaptic contact to a type I hair cell. GO:0002184 cytoplasmic translational termination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002184 The process resulting in the release of a polypeptide chain from the ribosome in the cytoplasm, usually in response to a termination codon. GO:0002185 creatine kinase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0002185 A protein complex having creatine kinase activity. GO:0099097 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0099097 GO:0099094 ligand-gated cation channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0099094 Enables the transmembrane transfer of an inorganic cation by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts. GO:0002186 cytosolic creatine kinase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0002186 A dimeric protein complex having creatine kinase activity. GO:0099095 ligand-gated anion channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0099095 Enables the transmembrane transfer of an inorganic anion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts. GO:0002187 mitochondrial creatine kinase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0002187 An octomeric protein complex having creatine kinase activity. GO:0099092 postsynaptic density, intracellular component biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099092 A network of proteins adjacent to the postsynaptic membrane forming an electron dense disc. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize neurotransmitter receptors in the adjacent membrane, such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components. GO:0002180 5-lipoxygenase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0002180 An nuclear membrane protein complex having arachidonate 5-lipoxygenase activity. GO:0002181 cytoplasmic translation biolink:BiologicalProcess go-plus goslim_pombe|goslim_yeast|goslim_drosophila http://purl.obolibrary.org/obo/GO_0002181 The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein. GO:0099093 calcium export from the mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099093 calcium ion transmembrane export from mitochondrion|mitochondrial calcium release|mitochondrial calcium ion export A process in which a calcium ion (Ca2+) is transported out of the mitochondrial matrix, and into the cytosol. GO:0099090 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0099090 GO:0002182 cytoplasmic translational elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002182 The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in the cytoplasm. GO:0099091 postsynaptic specialization, intracellular component biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099091 A network of proteins adjacent to the postsynaptic membrane. Its major components include the proteins that spatially and functionally organize neurotransmitter receptors in the adjacent membrane, such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components. GO:0002183 cytoplasmic translational initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002183 The process preceding formation of the peptide bond between the first two amino acids of a protein in the cytoplasm. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA. GO:0002190 cap-independent translational initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002190 The process where translation initiation recruits the 40S ribosomal subunits in a Cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate mRNA or circRNA translation. GO:0002199 zona pellucida receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0002199 sperm protein complex I A multisubunit complex comprising the chaperonin-containing T-complex and several other components involved in mediating sperm-oocyte Interaction. GO:0002195 2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine-tRNA biosynthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002195 The chemical reactions and pathways involved in the biosynthesis of 2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine (ms2io6A), a modified nucleoside present in position 37 (adjacent to and 3' of the anticodon) of tRNAs. GO:0002196 Ser-tRNA(Ala) hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0002196 Catalysis of the hydrolysis of misacylated Ser-tRNA(Ala). GO:0002197 xanthine dehydrogenase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0002197 A homodimeric protein complex having xanthine dehydrogenase activity. GO:0002198 obsolete S/G2 transition of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002198 S/G2 transition of mitotic cell cycle OBSOLETE. The transition from a cell in the S phase to the G2 phase. GO:0002191 cap-dependent translational initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002191 The process where the cap structure, composed of a 7- methylguanosine (m7G) group and associated cap-binding proteins, located at the 5' end of an mRNA molecule, which serves as a molecular tag that marks the spot where the 40S ribosomal subunit, is recruited and will then scan in a 5' to 3' direction until an AUG codon is encountered in an appropriate sequence context to initiate mRNA translation. GO:0002192 IRES-dependent translational initiation of linear mRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002192 The process where translation initiation recruits the 40S ribosomal subunits via an internal ribosome entry segment (IRES) before an AUG codon is encountered in an appropriate sequence context to initiate linear mRNA translation. GO:0002193 MAML1-RBP-Jkappa- ICN1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0002193 MAML1-CSL-ICN1|MAML1-RBP-Jkappa-Notch1 complex|MAML1-CSL-Notch1 complex A protein complex that consists of the intracellular domain of Notch1 (ICN1), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-1 (MAML1); the complex is involved in transcriptional activation in response to Notch-mediated signaling. GO:0002194 hepatocyte cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002194 The orderly movement of a hepatocyte during the development of the liver. Hepatocytes emerge from the hepatic epithelium, populating the septum transversum and lateral mesenchymal areas of the hepatic lobes. CHEBI:145267 PE(0:0/22:4) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145267 CHEBI:145269 PE(0:0/22:5) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145269 GO:0099078 BORC complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0099078 A protein complex that is invovled in positioning of the lysosome within the cytoplasm and which is composed of BLOC1S1, BLOC1S2, BORCS5, BORCS6, BORCS7, BORCS8, KXD1 and SNAPIN. The BORC complex recruits ARL8 at the cytosolic face of lysosomes and couples them to microtubule plus-end-directed kinesin motors. GO:0002166 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0002166 GO:0099079 actin body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0099079 An amorphous cytoskeletal structure consisting of aggregated actin filaments and associated proteins (including fibrin and capping protein) in which there is little or no actin filament turnover. In yeast (S. pombe and S. cerevisiae) these are found only in quiescent cells and are thought to serve as a reserve store of actin. PATO:0015006 polymeric biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PATO_0015006 A quality inhering in a structure by virtue of it consisting of many of repeated, similar or identical subunits, arranged in some orderly array. GO:0002167 VRK3/VHR/ERK complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0002167 A ternary complex consisting of VRK3, VHR (Dusp3), and ERK1 (Mapk3) existing in neuronal cells, and is involved in regulation of the ERK signaling pathway. GO:0002168 instar larval development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002168 The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. This begins with the newly hatched first-instar larva, through its maturation to the end of the last larval stage. An example of this process is found in Drosophila melanogaster. GO:0099076 mitochondrion to peroxisome transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099076 Transport from the mitochondrion to the peroxisome, mediated by mitochondrion-derived vesicles. GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0002169 mitochondrial 3-methylcrotonyl-CoA carboxylase holoenzyme|mitochondrial methylcrotonoyl-CoA carboxylase complex|mitochondrial MCCC complex A mitochondrial protein complex which is capable of 3-methylcrotonyl-CoA carboxylase activity. In mammals, at least, consists as a dodecamer of 6 alpha and 6 beta subunits. MCCC-alpha has a covalently bound biotin essential for the ATP-dependent carboxylation. MCCC-beta possesses carboxyltransferase activity which presumably is essential for binding to 3-methylcrotonyl-CoA. GO:0099077 histone-dependent DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0099077 DNA-binding activity that is dependent on binding to a histone. GO:0099074 mitochondrion to lysosome transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099074 Transport from the mitochondrion to the lysosome, mediated by mitochondrion-derived vesicles. GO:0002162 dystroglycan binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0002162 beta-dystroglycan binding|alpha-dystroglycan binding Interacting selectively and non-covalently with dystroglycan. Dystroglycan is glycoprotein found in non-muscle tissues as well as in muscle tissues, often in association with dystrophin. The native dystroglycan cleaved into two non-covalently associated subunits, alpha (N-terminal) and beta (C-terminal). GO:0099075 mitochondrion-derived vesicle mediated transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099075 Transport from the mitochondrion, mediated by mitochondrion derived vesicles. GO:0002163 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0002163 GO:0099072 regulation of postsynaptic membrane neurotransmitter receptor levels biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099072 Any process that regulates the the local concentration of neurotransmitter receptor at the postsynaptic membrane. GO:0002164 larval development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002164 The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. The larva is the early, immature form of an that at birth or hatching is fundamentally unlike its parent and must metamorphose before assuming the adult characters. CHEBI:145260 PE(0:0/20:3) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145260 GO:0099073 mitochondrion-derived vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0099073 MDV A vesicle derived via budding from a mitochondrion. These vesicles often contain inner membrane and, much more rarely, cristae. GO:0002165 instar larval or pupal development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002165 The process whose specific outcome is the progression of the instar larva or pupa over time, from its formation to the mature structure. An example of this process is found in Drosophila melanogaster. GO:0099070 static microtubule bundle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0099070 quiescent cell MT bundle|Q-MT bundle|quiescent cell microtubule bundle A microtubule bundle that has a constant length, and in which microtubule sliding does not take place. CHEBI:145262 PE(0:0/20:5) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145262 GO:0099071 dynamic microtubule bundle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0099071 A microtubule bundle that undergoes changes in length, and in which microtubule sliding takes place. GO:0002160 desmosome maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002160 The maintenance of a desmosome. A desmosome is a patch-like intercellular junctions found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an interspace of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm. CHEBI:145264 lysophosphatidylethanolamine 22:2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145264 GO:0002161 aminoacyl-tRNA editing activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0002161 aminoacyl-tRNA hydrolysis activity|amino acid proofreading activity The hydrolysis of an incorrectly aminoacylated tRNA. CHEBI:145265 PE(0:0/22:2) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145265 CHEBI:90616 N(6)-methyl-2'-deoxyadenosine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90616 CHEBI:90618 C-terminal Gly-Gly-AMP(1-) group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90618 CHEBI:90619 C-terminal N-glycylaminoethanethioic S-acid residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90619 CHEBI:90615 2'-deoxyadenosine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90615 CHEBI:90610 O-[S-2,3-dihydroxybenzoylpantetheine-4'-phosphoryl]-L-serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90610 CHEBI:145255 lysophosphatidylethanolamine 18:3 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145255 CHEBI:145257 PE(0:0/18:3) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145257 GO:0002177 manchette biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0002177 A tubular array of microtubules that extends from the perinuclear ring surrounding the spermatid nucleus to the flagellar axoneme. The manchette may also contain F-actin filaments. GO:0099089 establishment of endoplasmic reticulum localization to postsynapse biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099089 establishment of ER localization to postsynapse The directed movement of endoplasmic reticulum into a postsynaptic compartment such as a dendritic spine. GO:0002178 palmitoyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0002178 A protein complex with palmitoyltransferase activity. GO:0002179 homodimeric serine palmitoyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0002179 A homodimeric complex which transfers a palmitoyl group onto serine, forming 3-dehydro-D-sphinganine. GO:0099087 anterograde axonal transport of messenger ribonucleoprotein complex biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099087 anterograde axonal transport of mRNA RNP complex The directed movement of a messenger ribonucleoprotein complex along microtubules in axons, towards the presynapse. GO:0099088 axonal transport of messenger ribonucleoprotein complex biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099088 axonal transport of mRNA RNP complex The directed movement of a messenger ribonucleoprotein complex along microtubules in axons. GO:0002173 low-affinity IgM receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0002173 low affinity IgM receptor activity Combining with low affinity with an immunoglobulin of an IgM isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0099085 DIF dechlorinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0099085 1-[(3,5-dichloro-2,6-dihydroxy-4-methoxy)phenyl]hexan-1-one 3(5)-dechlorinase activity|DIF-1 dechlorinase activity|differentiation-inducing factor 1 dechlorinase activity|1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one 3(5)-dechlorinase activity|DIF-1 3(5)-dechlorinase activity|differentiation-inducing factor dechlorinase activity Catalysis of the reaction: 1-[(3,5-dichloro-2,6-dihydroxy-4-methoxy)phenyl]hexan-1-one => 1-[(3-chloro-2,6-dihydroxy-4-methoxy)phenyl]hexan-1-one + Cl-. GO:0002174 mammary stem cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002174 The expansion of a mammary stem cell population by cell division. Mammary stem cells are a source of cells for growth of the mammary gland during puberty and gestation. These cells can give rise to both the luminal and myoepithelial cell types of the gland, and can regenerate the entire organ. GO:0099086 synaptonemal structure biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0099086 A proteinaceous scaffold found between homologous chromosomes during meiosis. GO:0002175 protein localization to paranode region of axon biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002175 protein localisation to paranode region of axon A cellular protein localization process in which a protein is transported to, or maintained at, the paranode region of an axon. GO:0099083 retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099083 Modulation of synaptic transmittion by cell-cell signaling across the synaptic cleft from postsynapse to presynapse, mediated by a neuropeptide. GO:0002176 male germ cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002176 The multiplication or reproduction of male germ cells, resulting in the expansion of a cell population. CHEBI:145250 PE(0:0/16:1) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145250 GO:0099084 postsynaptic specialization organization biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099084 post-synaptic specialization organization|postsynaptic specialization organisation|post synaptic specialization organization A process that results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic specialization, a structure that lies adjacent to the cytoplasmic face of the postsynaptic membrane. CHEBI:145251 PE(0:0/14:1) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145251 GO:0099081 supramolecular polymer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0099081 A polymeric supramolecular structure. GO:0099082 retrograde trans-synaptic signaling by neuropeptide biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099082 Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a neuropeptide. GO:0002170 high-affinity IgA receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0002170 high affinity IgA receptor activity Combining with high affinity with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. CHEBI:145252 PE(0:0/18:1) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145252 GO:0002171 low-affinity IgA receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0002171 low affinity IgA receptor activity Combining with low affinity with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0002172 high-affinity IgM receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0002172 high affinity IgM receptor activity Combining with high affinity with an immunoglobulin of an IgM isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0099080 supramolecular complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0099080 A cellular component that consists of an indeterminate number of proteins or macromolecular complexes, organized into a regular, higher-order structure such as a polymer, sheet, network or a fiber. CHEBI:90605 monodecanoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90605 CHEBI:90602 uridylyl-L-tyrosine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90602 GO:0002148 hypochlorous acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002148 HClO metabolic process|hypochlorous acid metabolism|hypochlorite metabolic process|HOCl metabolic process The chemical reactions and pathways involving hypochlorous acid. CHEBI:145245 lysophosphatidylethanolamine 14:1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145245 GO:0002149 hypochlorous acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002149 hypochlorous acid biosynthesis|HOCl biosynthetic process|HClO biosynthetic process|hypochlorite biosynthetic process The chemical reactions and pathways resulting in the formation of hypochlorous acid. CHEBI:145247 lysophosphatidylethanolamine 16:1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145247 GO:0002144 cytosolic tRNA wobble base thiouridylase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0002144 tRNA thiouridylase|Cut1-Cut2 complex A complex of two proteins involved in the thiolation of uridine 34 (U34) of tRNAs decoding two-family box triplets. GO:0002145 4-amino-5-hydroxymethyl-2-methylpyrimidine diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0002145 MetaCyc:RXN0-3543|RHEA:27914 HMP-PP diphosphatase|HMP-PP pyrophosphatase Catalysis of the reaction: 4-amino-5-hydroxymethyl-2-methylpyrimidine pyrophosphate + H2O = hydroxymethylpyrimidine phosphate + phosphate + H(+). GO:0002146 obsolete steroid hormone receptor import into nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002146 steroid hormone receptor nuclear translocation OBSOLETE. The directed movement of a steroid hormone receptor into the nucleus. GO:0002147 obsolete glucocorticoid receptor import into nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002147 glucocorticoid receptor nuclear translocation OBSOLETE. The directed movement of a glucocorticoid receptor into the nucleus. GO:0002140 stereocilia tip link biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0002140 A stereocilia link that is formed by a fine filament running more or less vertically upward from the tip of each shorter stereocilium to attach at a higher point on its adjacent taller neighbor. Tilting the bundle puts tension on the filaments, which pull on mechanically gated ion channels in the membrane of the stereocilia. GO:0002141 stereocilia ankle link biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0002141 A stereocilia coupling link that is composed of a fine filament present in developing stereocilia that couples the bases of individual stereocilia to one another. They are not present in mature stereocilia. GO:0002142 stereocilia ankle link complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0002142 A complex of proteins that connect growing stereocilia in developing cochlear hair cells, composed of Vlgr1, usherin, vezatin, and whirlin. GO:0002143 tRNA wobble position uridine thiolation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002143 wobble position s2U biosynthesis|tRNA wobble uridine thiolation The process in which a uridine residue at position 34 in the anticodon of a tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from cysteine to position C2 by several steps. CHEBI:145240 2-methylpyrrolidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145240 GO:0016789 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016789 GO:0016785 transferase activity, transferring selenium-containing groups biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016785 EC:2.9.1.-|EC:2.9.-.- selenotransferase activity Catalysis of the transfer of a selenium-containing group from one compound (donor) to another (acceptor). GO:0016786 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016786 GO:0016787 hydrolase activity biolink:MolecularActivity go-plus goslim_mouse|goslim_candida|goslim_yeast|goslim_plant|goslim_pir|goslim_metagenomics|goslim_aspergillus|goslim_chembl http://purl.obolibrary.org/obo/GO_0016787 Reactome:R-HSA-6788295|Reactome:R-HSA-5694583|Reactome:R-HSA-1236938|Reactome:R-HSA-8938314|Reactome:R-HSA-6786190|Reactome:R-HSA-2029475|Reactome:R-HSA-5695964|EC:3.-.-.-|Reactome:R-HSA-8952137 Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3. GO:0016788 hydrolase activity, acting on ester bonds biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0016788 Reactome:R-HSA-9023617|Reactome:R-HSA-9023619|EC:3.1.-.-|Reactome:R-HSA-162729 esterase activity Catalysis of the hydrolysis of any ester bond. GO:0016781 phosphotransferase activity, paired acceptors biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016781 EC:2.7.9.- Catalysis of the transfer of two phosphate groups from a donor, such as ATP, to two different acceptors. GO:0016782 transferase activity, transferring sulfur-containing groups biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016782 EC:2.8.-.- transferase activity, transferring sulphur-containing groups Catalysis of the transfer of a sulfur-containing group from one compound (donor) to another (acceptor). CHEBI:90631 5-hydroperoxy-15-HETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90631 GO:0016783 sulfurtransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016783 Reactome:R-HSA-1614618|Reactome:R-HSA-6782264|EC:2.8.1.-|Reactome:R-HSA-947538 sulphurtransferase activity|tRNA sulfurtransferase activity Catalysis of the transfer of sulfur atoms from one compound (donor) to another (acceptor). CHEBI:90632 5(S)-HETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90632 GO:0016784 3-mercaptopyruvate sulfurtransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016784 Reactome:R-HSA-9013533|RHEA:21740|Reactome:R-HSA-9012721|EC:2.8.1.2|MetaCyc:MERCAPYSTRANS-RXN|Reactome:R-HSA-9034756|Reactome:R-HSA-9013471 beta-mercaptopyruvate sulfurtransferase activity|mercaptopyruvate sulfurtransferase activity|3-mercaptopyruvate:cyanide sulfurtransferase activity|3-mercaptopyruvate sulphurtransferase activity Catalysis of the reaction: 3-mercaptopyruvate + cyanide = pyruvate + thiocyanate. GO:0016780 phosphotransferase activity, for other substituted phosphate groups biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016780 EC:2.7.8.-|Reactome:R-HSA-163069|Reactome:R-HSA-162742 Catalysis of the transfer of a substituted phosphate group, other than diphosphate or nucleotidyl residues, from one compound (donor) to a another (acceptor). GO:0002159 desmosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002159 A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm. GO:0002155 regulation of thyroid hormone mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002155 regulation of thyroid hormone mediated signalling pathway Any process that modulates the frequency, rate or extent of a thyroid hormone mediated signaling pathway. GO:0002156 negative regulation of thyroid hormone mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002156 negative regulation of thyroid hormone mediated signalling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of thyroid hormone mediated signaling pathway. GO:0002157 positive regulation of thyroid hormone mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002157 positive regulation of thyroid hormone mediated signalling pathway Any process that increases the frequency, rate or extent of thyroid hormone mediated signaling pathway. GO:0002158 osteoclast proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002158 The multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes. GO:0002151 G-quadruplex RNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0002151 G quartet RNA binding|G-quartet binding|G quartet binding|G quadruplex binding Interacting selectively and non-covalently with G-quadruplex RNA structures, in which groups of four guanines adopt a flat, cyclic hydrogen-bonding arrangement known as a guanine tetrad. GO:0002152 bile acid conjugation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002152 The process in which bile acids are covalently linked to taurine or glycine. GO:0002153 steroid receptor RNA activator RNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0002153 SRA binding Interacting selectively and non-covalently with the steroid receptor RNA activator RNA (SRA). SRA enhances steroid hormone receptor transcriptional activity as an RNA transcript by an indirect mechanism that does not involve SRA-steroid receptor binding. GO:0002154 thyroid hormone mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002154 thyroid hormone mediated signalling pathway A series of molecular signals mediated by the detection of a thyroid hormone. GO:0002150 hypochlorous acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002150 HOCl catabolic process|hypochlorous acid catabolism|HClO catabolic process|hypochlorite catabolic process The chemical reactions and pathways resulting in the breakdown of hypochlorous acid. CHEBI:90628 benzyl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90628 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016796 EC:3.1.15.- exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5' phosphomonoesters Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters. GO:0016797 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016797 EC:3.1.16.- Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end to yield 3' phosphomonoesters. GO:0016798 hydrolase activity, acting on glycosyl bonds biolink:MolecularActivity go-plus goslim_generic|goslim_chembl|goslim_yeast|goslim_drosophila http://purl.obolibrary.org/obo/GO_0016798 EC:3.2.-.-|Reactome:R-HSA-2065233|Reactome:R-HSA-1793176 N-glycosylase|glycosylase|glycosidase activity Catalysis of the hydrolysis of any glycosyl bond. GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016799 EC:3.2.2.- Catalysis of the hydrolysis of any N-glycosyl bond. GO:0016792 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016792 GO:0016793 triphosphoric monoester hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016793 Reactome:R-HSA-8866601|RHEA:46148|EC:3.1.5.- Catalysis of the hydrolysis of a triphosphoester to give a triphosphate group and a free hydroxyl group. GO:0016794 diphosphoric monoester hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016794 EC:3.1.7.- Catalysis of the hydrolysis of a diphosphoester to give a diphosphate group and a free hydroxyl group. GO:0016795 phosphoric triester hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016795 EC:3.1.8.- Catalysis of the hydrolysis of a phosphoric triester. GO:0016790 thiolester hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016790 EC:3.1.2.- thiolesterase activity Catalysis of the reaction: RCO-SR' + H2O = RCOOH + HSR'. This reaction is the hydrolysis of a thiolester bond, an ester formed from a carboxylic acid and a thiol (i.e., RCO-SR'), such as that found in acetyl-coenzyme A. GO:0016791 phosphatase activity biolink:MolecularActivity go-plus goslim_generic|goslim_chembl|goslim_yeast|goslim_candida|goslim_drosophila|goslim_aspergillus|goslim_metagenomics http://purl.obolibrary.org/obo/GO_0016791 Reactome:R-HSA-9636457|MetaCyc:4-NITROPHENYLPHOSPHATASE-RXN|Reactome:R-HSA-4419986|EC:3.1.3.- 4-nitrophenylphosphatase activity|phosphoric monoester hydrolase activity|p-nitrophenylphosphatase activity|ecto-p-nitrophenyl phosphatase activity|NPPase activity|para-nitrophenyl phosphatase activity|p-nitrophenylphosphate phosphohydrolase activity|phosphatase|4-nitrophenylphosphate phosphohydrolase activity|K-pNPPase activity|PNPPase activity|nitrophenyl phosphatase activity Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate. GO:0002126 instrumental aggressive behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002126 instrumental aggression Aggressive behavior directed towards obtaining some goal, considered to be a learned response to a situation. GO:0002127 tRNA wobble base cytosine methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002127 wobble position m5C biosynthesis The process in which the base of cytosine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the C5 position. CHEBI:75017 1-lauroyl-2-palmitoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75017 GO:0002128 tRNA nucleoside ribose methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002128 The process that results in the modification of the sugar of a nucleoside in tRNA at the 2'O position. GO:0002129 wobble position guanine ribose methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002129 The process in which the ribose of guanosine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position. CHEBI:75018 1-palmitoyl-2-lauroyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75018 GO:0002122 fear-induced aggressive behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002122 fear-induced aggression Aggressive behavior associated with attempts to flee from a threat. GO:0002123 irritable aggressive behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002123 irritable aggression Aggressive behavior induced by frustration and directed against an available target. GO:0002124 territorial aggressive behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002124 territorial aggression Aggressive behavior performed in defence of a fixed area against intruders, typically conspecifics. GO:0002125 maternal aggressive behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002125 maternal aggression Aggressive behavior of a female to protect her offspring from a threat. GO:0002120 obsolete predatory behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002120 predatory aggression|predatory aggressive behavior OBSOLETE. Aggressive behavior involving attack on prey by a predator. GO:0002121 inter-male aggressive behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002121 inter-male aggression Aggressive behavior based on competition between males of the same species over access to resources such as females, dominance, status, etc. and characterized by noise, threats, and is often less injurious. GO:0016767 geranylgeranyl-diphosphate geranylgeranyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016767 EC:2.5.1.32|RHEA:22296|MetaCyc:2.5.1.32-RXN geranylgeranyl-diphosphate:geranylgeranyl-diphosphate geranylgeranyltransferase activity|prephytoene-diphosphate synthase activity|phytoene synthetase activity|PSase activity Catalysis of the reaction: 2 geranylgeranyl diphosphate = diphosphate + prephytoene diphosphate. CHEBI:51080 nitrate ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51080 GO:0016768 spermine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016768 MetaCyc:SPERMINE-SYNTHASE-RXN|EC:2.5.1.22|RHEA:19973|Reactome:R-HSA-351210 S-adenosylmethioninamine:spermidine 3-aminopropyltransferase activity|spermine synthetase activity|spermidine aminopropyltransferase activity Catalysis of the reaction: S-adenosylmethioninamine + spermidine = 5'-methylthioadenosine + spermine. CHEBI:51081 nitrates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51081 GO:0016769 transferase activity, transferring nitrogenous groups biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016769 EC:2.6.-.- transferase activity, transferring other nitrogenous groups Catalysis of the transfer of a nitrogenous group from one compound (donor) to another (acceptor). GO:0016763 transferase activity, transferring pentosyl groups biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016763 Reactome:R-HSA-112266|Reactome:R-HSA-112265|EC:2.4.2.- pentosyltransferase activity Catalysis of the transfer of a pentosyl group from one compound (donor) to another (acceptor). GO:0016764 obsolete transferase activity, transferring other glycosyl groups biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016764 transferase activity, transferring other glycosyl groups OBSOLETE. Catalysis of the transfer of a glycosyl group, other than hexosyl or pentosyl, from one compound (donor) to another (acceptor). GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups biolink:MolecularActivity go-plus goslim_chembl|goslim_drosophila|goslim_generic http://purl.obolibrary.org/obo/GO_0016765 Reactome:R-HSA-4419978|Reactome:R-HSA-4755545|EC:2.5.1.-|Reactome:R-HSA-6782893|EC:2.5.-.- transferase activity, transferring alkyl or aryl groups, other than methyl groups Catalysis of the transfer of an alkyl or aryl (but not methyl) group from one compound (donor) to another (acceptor). GO:0016766 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016766 GO:0016760 cellulose synthase (UDP-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016760 RHEA:19929|EC:2.4.1.12|MetaCyc:CELLULOSE-SYNTHASE-UDP-FORMING-RXN UDP-glucose-beta-D-glucan glucosyltransferase activity|beta-glucan synthase activity|UDPglucose-beta-glucan glucosyltransferase activity|UDP-glucose-cellulose glucosyltransferase activity|UDP-glucose-1,4-beta-glucan glucosyltransferase activity|1,4-beta-D-glucan synthase activity|UDPglucose-cellulose glucosyltransferase activity|beta-1,4-glucan synthase activity|GS-I|uridine diphosphoglucose-cellulose glucosyltransferase activity|uridine diphosphoglucose-1,4-beta-glucan glucosyltransferase activity|UDPglucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase activity|beta-1,4-glucosyltransferase activity|1,4-beta-glucan synthase activity|UDP-glucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase activity|beta-1,4-glucan synthetase activity|glucan synthase activity Catalysis of the reaction: UDP-glucose + ((1,4)-beta-D-glucosyl)(n) = UDP + ((1,4)-beta-D-glucosyl)(n+1). GO:0016761 cellulose synthase (GDP-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016761 RHEA:17797|MetaCyc:CELLULOSE-SYNTHASE-GDP-FORMING-RXN|EC:2.4.1.29 cellulose synthase (guanosine diphosphate-forming) activity|GDPglucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase activity|GDP-glucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase activity|GDP-glucose-beta-D-glucan glucosyltransferase activity|GDP-glucose-cellulose glucosyltransferase activity|guanosine diphosphoglucose-cellulose glucosyltransferase activity|guanosine diphosphoglucose-1,4-beta-glucan glucosyltransferase activity Catalysis of the reaction: GDP-glucose + ((1,4)-beta-D-glucosyl)(n) = GDP + ((1,4)-beta-D-glucosyl)(n+1). GO:0016762 xyloglucan:xyloglucosyl transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016762 MetaCyc:2.4.1.207-RXN|EC:2.4.1.207 endoxyloglucan transferase activity|xyloglucan:xyloglucan xyloglucanotransferase activity|endo-xyloglucan transferase activity|xyloglucan endotransglucosylase activity Catalysis of the cleavage of a beta-(1->4) bond in the backbone of a xyloglucan and transfers the xyloglucanyl segment on to O-4 of the non-reducing terminal glucose residue of an acceptor, which can be a xyloglucan or an oligosaccharide of xyloglucan. CHEBI:51086 chemical role biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51086 GO:0002137 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0002137 GO:0002138 retinoic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002138 retinoic acid anabolic process The chemical reactions and pathways resulting in the biosynthesis of retinoic acid, one of the three components that makes up vitamin A. GO:0002139 stereocilia coupling link biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0002139 A structure involved in coupling stereocilia to one another in sensory hair cells There are four morphologically distinct types: tip links, horizontal top connectors, shaft connectors and ankle links. Tip links and horizontal top connectors are the only inter-stereocilia links associated with mature cochlea, whereas ankle links appear during development of the auditory hair bundle. CHEBI:75028 1-(alpha,beta-saturated alkyl)-2-acyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75028 CHEBI:75029 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoserine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75029 GO:0002133 polycystin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0002133 A stable heterodimeric complex composed of polycystin-1 and polycystin-2. GO:0002134 UTP binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0002134 Interacting selectively and non-covalently with UTP, uridine 5'-triphosphate. CHEBI:145217 epoxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145217 GO:0002135 CTP binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0002135 Interacting selectively and non-covalently with CTP, cytidine 5'-triphosphate. GO:0002136 tRNA wobble base lysidine biosynthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002136 The process in which the carbonyl of cytosine at position 34 of a tRNA is post-transcriptionally replaced by lysine. GO:0002130 wobble position ribose methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002130 The process in which the ribose base of the nucleotide at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'O position. GO:0002131 wobble position cytosine ribose methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002131 The process in which the ribose of cytidine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position. GO:0002132 wobble position uridine ribose methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002132 The process in which the ribose of uridine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position. GO:0016778 diphosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016778 EC:2.7.6.- Catalysis of the transfer of a diphosphate group from one compound (donor) to a another (acceptor). GO:0016779 nucleotidyltransferase activity biolink:MolecularActivity go-plus goslim_drosophila|goslim_aspergillus|goslim_metagenomics|goslim_generic|goslim_chembl|goslim_yeast|goslim_candida http://purl.obolibrary.org/obo/GO_0016779 Reactome:R-HSA-6782434|EC:2.7.7.- Catalysis of the transfer of a nucleotidyl group to a reactant. GO:0016774 phosphotransferase activity, carboxyl group as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016774 EC:2.7.2.- Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a carboxyl group (acceptor). GO:0016775 phosphotransferase activity, nitrogenous group as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016775 EC:2.7.3.- Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a nitrogenous group (acceptor). GO:0016776 phosphotransferase activity, phosphate group as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016776 EC:2.7.4.- Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a phosphate group (acceptor). GO:0016777 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016777 GO:0016770 oximinotransaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016770 EC:2.6.3.- Catalysis of the reversible transfer of an oxime group to an acceptor. CHEBI:75023 Ins-1-P-6-Man-1-2-Ins-1-P-Cer C(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75023 GO:0016771 obsolete transferase activity, transferring other nitrogenous groups biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016771 transferase activity, transferring other nitrogenous groups OBSOLETE. Catalysis of the transfer of a nitrogenous group, other than amino, amidino or oxime, from one compound (donor) to another (acceptor). CHEBI:51078 13-sophorosyloxydocosanoate 6',6''-diacetate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51078 CHEBI:75020 1-palmitoyl-sn-glycero-3-phosphoserine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75020 GO:0016772 transferase activity, transferring phosphorus-containing groups biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0016772 EC:2.7.-.- Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor). GO:0016773 phosphotransferase activity, alcohol group as acceptor biolink:MolecularActivity go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0016773 EC:2.7.1.-|Reactome:R-HSA-2161193 Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor). CHEBI:75026 1-stearoyl-2-palmitoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_75026 CHEBI:51075 sophorolipid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_51075 GO:1905490 negative regulation of sensory neuron axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905490 down-regulation of sensory neuron axon guidance|downregulation of sensory neuron axon guidance|down regulation of sensory neuron axon guidance|inhibition of sensory neuron axon guidance Any process that stops, prevents or reduces the frequency, rate or extent of sensory neuron axon guidance. GO:1905491 positive regulation of sensory neuron axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905491 up regulation of sensory neuron axon guidance|upregulation of sensory neuron axon guidance|up-regulation of sensory neuron axon guidance|activation of sensory neuron axon guidance Any process that activates or increases the frequency, rate or extent of sensory neuron axon guidance. GO:1905492 positive regulation of branching morphogenesis of a nerve biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905492 upregulation of branching morphogenesis of a nerve|up-regulation of branching morphogenesis of a nerve|activation of branching morphogenesis of a nerve|up regulation of branching morphogenesis of a nerve Any process that activates or increases the frequency, rate or extent of branching morphogenesis of a nerve. GO:1905493 regulation of G-quadruplex DNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905493 regulation of G-quartet DNA binding|regulation of G-quartet binding|regulation of tetraplex DNA binding|regulation of quadruplex DNA binding|regulation of G-DNA binding|regulation of G quadruplex DNA binding|regulation of G quartet DNA binding|regulation of G quartet binding Any process that modulates the frequency, rate or extent of G-quadruplex DNA binding. GO:1905494 negative regulation of G-quadruplex DNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905494 down-regulation of G-quadruplex DNA binding|inhibition of tetraplex DNA binding|negative regulation of G-DNA binding|down-regulation of G-DNA binding|negative regulation of G quartet DNA binding|negative regulation of quadruplex DNA binding|down-regulation of G quartet DNA binding|down regulation of G-quartet DNA binding|down-regulation of quadruplex DNA binding|inhibition of G-DNA binding|downregulation of G-quadruplex DNA binding|downregulation of G-quartet DNA binding|down regulation of G-quadruplex DNA binding|down-regulation of G quadruplex DNA binding|inhibition of G quartet DNA binding|down regulation of tetraplex DNA binding|negative regulation of G quadruplex DNA binding|inhibition of G-quadruplex DNA binding|downregulation of quadruplex DNA binding|downregulation of tetraplex DNA binding|down-regulation of G-quartet DNA binding|negative regulation of G-quartet DNA binding|down regulation of quadruplex DNA binding|down regulation of G-DNA binding|inhibition of quadruplex DNA binding|downregulation of G quadruplex DNA binding|downregulation of G-DNA binding|down regulation of G quartet DNA binding|inhibition of G-quartet DNA binding|negative regulation of tetraplex DNA binding|down regulation of G quadruplex DNA binding|down-regulation of tetraplex DNA binding|inhibition of G quadruplex DNA binding|downregulation of G quartet DNA binding Any process that stops, prevents or reduces the frequency, rate or extent of G-quadruplex DNA binding. GO:1905495 positive regulation of G-quadruplex DNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905495 activation of quadruplex DNA binding|up-regulation of quadruplex DNA binding|up regulation of G quartet DNA binding|up-regulation of tetraplex DNA binding|activation of G quartet DNA binding|positive regulation of G quartet DNA binding|upregulation of G-quartet DNA binding|up regulation of G-quadruplex DNA binding|up-regulation of G quadruplex DNA binding|activation of G quadruplex DNA binding|up-regulation of G-DNA binding|positive regulation of quadruplex DNA binding|upregulation of tetraplex DNA binding|up regulation of quadruplex DNA binding|up-regulation of G quartet DNA binding|up regulation of G-quartet DNA binding|activation of G-quartet DNA binding|positive regulation of G-quartet DNA binding|upregulation of G-quadruplex DNA binding|upregulation of G-DNA binding|positive regulation of G quadruplex DNA binding|up regulation of G quadruplex DNA binding|up regulation of tetraplex DNA binding|activation of tetraplex DNA binding|positive regulation of tetraplex DNA binding|upregulation of quadruplex DNA binding|upregulation of G quartet DNA binding|up-regulation of G-quadruplex DNA binding|activation of G-quadruplex DNA binding|up-regulation of G-quartet DNA binding|up regulation of G-DNA binding|activation of G-DNA binding|positive regulation of G-DNA binding|upregulation of G quadruplex DNA binding Any process that activates or increases the frequency, rate or extent of G-quadruplex DNA binding. GO:1905496 regulation of triplex DNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905496 Any process that modulates the frequency, rate or extent of triplex DNA binding. GO:1905497 negative regulation of triplex DNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905497 down-regulation of triplex DNA binding|inhibition of triplex DNA binding|down regulation of triplex DNA binding|downregulation of triplex DNA binding Any process that stops, prevents or reduces the frequency, rate or extent of triplex DNA binding. CHEBI:16618 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16618 CHEBI:16619 (2-trans,6-trans)-farnesol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16619 GO:1905498 positive regulation of triplex DNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905498 up-regulation of triplex DNA binding|upregulation of triplex DNA binding|up regulation of triplex DNA binding|activation of triplex DNA binding Any process that activates or increases the frequency, rate or extent of triplex DNA binding. GO:1905488 positive regulation of anterior/posterior axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905488 up-regulation of anterior/posterior axon pathfinding|positive regulation of anterior-posterior axon guidance|upregulation of anterior/posterior axon pathfinding|up regulation of anterior-posterior axon guidance|up regulation of anterior/posterior axon guidance|upregulation of anterior-posterior axon guidance|up regulation of anterior/posterior axon pathfinding|activation of anterior/posterior axon pathfinding|upregulation of anterior/posterior axon guidance|positive regulation of anterior/posterior axon pathfinding|up-regulation of anterior-posterior axon guidance|activation of anterior-posterior axon guidance|up-regulation of anterior/posterior axon guidance|activation of anterior/posterior axon guidance Any process that activates or increases the frequency, rate or extent of anterior/posterior axon guidance. CHEBI:16616 2-methylpropanal O-methyloxime biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16616 CHEBI:16617 1-acylglycerophosphoinositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16617 GO:1905489 regulation of sensory neuron axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905489 Any process that modulates the frequency, rate or extent of sensory neuron axon guidance. CHEBI:16615 biotin amide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16615 GO:0075280 regulation of uredinium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075280 Any process that modulates the frequency, rate or extent of uredinium development, a process that leads to the formation of a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores. CHEBI:16613 glutathionylspermidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16613 GO:0075281 positive regulation of uredinium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075281 Any process that activates, maintains or increases the frequency, rate or extent of uredinium development, a process that leads to the formation of a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores. CHEBI:16610 spermidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16610 GO:0075282 negative regulation of uredinium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075282 Any process that stops, prevents, or reduces the frequency, rate or extent of uredinium development, a process that leads to the formation of a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores. GO:0075283 sporulation resulting in formation of a multicellular or syncytial spore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075283 multicellular or syncytial spore formation by sporulation The process whose specific outcome is the progression of a multicellular or syncytial spore via septations over time, from its initiation to the mature structure. GO:0075284 asexual sporulation resulting in formation of a multicellular or syncytial spore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075284 The formation of a multicellular or syncytial spore via septations derived from mitosis. GO:0075285 sexual sporulation resulting in formation of a multicellular or syncytial spore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075285 The formation of multicellular or syncytial spore via septations derived from meiosis. A multicellular or syncytial spore is a structure that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction. GO:0075286 regulation of sporangiospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075286 Any process that modulates the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm. GO:0075287 positive regulation of sporangiospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075287 Any process that activates, maintains or increases the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm. GO:0075288 negative regulation of sporangiospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075288 Any process that stops, prevents, or reduces the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm. GO:0075289 aplanospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075289 The process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell. CHEBI:16609 2-dehydro-D-glucopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16609 CHEBI:16607 4-aminoimidazole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16607 CHEBI:16608 5alpha-cholest-8-en-3beta-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16608 CHEBI:16605 allyl alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16605 GO:1905499 trichome papilla formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905499 trichome papilla assembly The aggregation, arrangement and bonding together of a set of components to form a trichome papilla. CHEBI:16606 N-benzoyl-4-hydroxyanthranilic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16606 CHEBI:16603 DIMBOA glucoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16603 CHEBI:16602 trichloroethene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16602 GO:0075270 negative regulation of aecium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075270 Any process that stops, prevents, or reduces the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed. GO:0075271 zygosporangium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075271 The process in which a fruiting body called zygosporangium is formed. A zygosporangium is a thick-walled structure in which spores are produced, and is characteristic of the Zygomycetes. CHEBI:16600 mesaconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16600 GO:0075272 regulation of zygosporangium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075272 Any process that modulates the frequency, rate or extent of zygosporangium development, a process in which a fruiting body called zygosporangium is formed. GO:0075273 positive regulation of zygosporangium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075273 Any process that activates, maintains or increases the frequency, rate or extent of zygosporangium development, a process in which a fruiting body called zygosporangium is formed. GO:0075274 negative regulation of zygosporangium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075274 Any process that stops, prevents, or reduces the frequency, rate or extent of zygosporangium development, a process in which a fruiting body called zygosporangium is formed. GO:0075275 telium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075275 The process that leads to the development of a telium, which is a teliospore-bearing sorus of the rust fungi. GO:0075276 regulation of telium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075276 Any process that modulates the frequency, rate or extent of telium development, a process that leads to the formation of a teliospore-bearing sorus of the rust fungi. GO:0075277 positive regulation of telium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075277 Any process that activates, maintains or increases the frequency, rate or extent of telium development, a process that leads to the formation of a teliospore-bearing sorus of the rust fungi. GO:0075278 negative regulation of telium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075278 Any process that stops, prevents, or reduces the frequency, rate or extent of telium development, a process that leads to the formation of a teliospore-bearing sorus of the rust fungi. GO:0075279 uredinium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075279 development of uredium The process that leads to the formation of a uredinium, a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores. GO:2000805 negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000805 negative regulation of transcription termination from Pol II promoter, poly(A) coupled|negative regulation of transcription termination from Pol II promoter, RNA polymerase(A) coupled|negative regulation of termination of RNA polymerase II transcription, polyadenylation-coupled Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled. GO:2000806 positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000806 positive regulation of transcription termination from Pol II promoter, RNA polymerase(A) coupled|positive regulation of termination of RNA polymerase II transcription, polyadenylation-coupled|positive regulation of transcription termination from Pol II promoter, poly(A) coupled Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled. GO:2000807 regulation of synaptic vesicle clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000807 Any process that modulates the frequency, rate or extent of synaptic vesicle clustering. GO:2000808 negative regulation of synaptic vesicle clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000808 Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle clustering. GO:2000809 positive regulation of synaptic vesicle clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000809 Any process that activates or increases the frequency, rate or extent of synaptic vesicle clustering. GO:2000800 regulation of endocardial cushion to mesenchymal transition involved in heart valve formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000800 regulation of endocardial cushion to mesenchymal transition involved in valve formation Any process that modulates the frequency, rate or extent of endocardial cushion to mesenchymal transition involved in heart valve formation. GO:2000801 negative regulation of endocardial cushion to mesenchymal transition involved in heart valve formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000801 negative regulation of endocardial cushion to mesenchymal transition involved in valve formation Any process that stops, prevents or reduces the frequency, rate or extent of endocardial cushion to mesenchymal transition involved in heart valve formation. GO:2000802 positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000802 positive regulation of endocardial cushion to mesenchymal transition involved in valve formation Any process that activates or increases the frequency, rate or extent of endocardial cushion to mesenchymal transition involved in heart valve formation. GO:2000803 endosomal signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000803 endosome-based signaling|signalling cascade in endosome|signaling cascade in endosome|signalling pathway in endosome|signaling from endosome|signaling pathway in endosome The process in which a signal is passed on to downstream components located at the endosome. Endosomes can provide important intracellular signaling platforms and provide spatial and temporal control over signal transduction. GO:2000804 regulation of termination of RNA polymerase II transcription, poly(A)-coupled biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000804 regulation of transcription termination from Pol II promoter, RNA polymerase(A) coupled|regulation of termination of RNA polymerase II transcription, polyadenylation-coupled|regulation of transcription termination from Pol II promoter, poly(A) coupled Any process that modulates the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled. CHEBI:16638 3-methylbutanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16638 CHEBI:16639 4-methoxybenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16639 CHEBI:16634 raffinose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16634 CHEBI:16635 Met-tRNA(Met) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16635 CHEBI:16632 vanillate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16632 CHEBI:16633 L-selenocysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16633 CHEBI:16630 3-dehydroshikimate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16630 CHEBI:16631 vitexin 2''-O-beta-D-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16631 GO:2000816 negative regulation of mitotic sister chromatid separation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000816 negative regulation of mitotic sister chromatid resolution|negative regulation of mitotic chromosome separation|negative regulation of sister chromatid separation during mitosis|negative regulation of chromosome separation during mitosis Any process that stops, prevents or reduces the frequency, rate or extent of mitotic sister chromatid separation. GO:2000817 regulation of histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000817 regulation of histone H3-T3 phosphorylation involved in chromosomal passenger complex localization to kinetochore|regulation of histone H3-T3 phosphorylation involved in chromosome passenger complex localisation to kinetochore|regulation of histone H3-T3 phosphorylation involved in CPC localization to kinetochore|regulation of histone H3-T3 phosphorylation involved in CPC complex localization to kinetochore Any regulation of histone H3-T3 phosphorylation that is involved in chromosome passenger complex localization to kinetochore. GO:2000818 negative regulation of myoblast proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000818 Any process that stops, prevents or reduces the frequency, rate or extent of myoblast proliferation. GO:2000819 regulation of nucleotide-excision repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000819 regulation of NER|regulation of pyrimidine-dimer repair, DNA damage excision|regulation of interstrand crosslink repair|regulation of intrastrand cross-link repair Any process that modulates the frequency, rate or extent of nucleotide-excision repair. GO:0099243 extrinsic component of synaptic membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099243 The component of the synaptic membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:0099240 intrinsic component of synaptic membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099240 intrinsic to synaptic membrane The component of the synaptic membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:2000810 regulation of bicellular tight junction assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000810 regulation of tight junction formation Any process that modulates the frequency, rate or extent of tight junction assembly. GO:2000811 negative regulation of anoikis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000811 negative regulation of detachment induced cell death|negative regulation of suspension induced apoptosis Any process that stops, prevents or reduces the frequency, rate or extent of anoikis. GO:2000812 regulation of barbed-end actin filament capping biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000812 regulation of barbed-end F-actin capping activity|regulation of plus-end actin filament capping activity|regulation of barbed-end actin capping activity|regulation of plus-end F-actin capping activity Any process that modulates the frequency, rate or extent of barbed-end actin filament capping. GO:2000813 negative regulation of barbed-end actin filament capping biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000813 negative regulation of barbed-end F-actin capping activity|negative regulation of barbed-end actin capping activity|negative regulation of plus-end F-actin capping activity|negative regulation of plus-end actin filament capping activity Any process that stops, prevents or reduces the frequency, rate or extent of barbed-end actin filament capping. GO:2000814 positive regulation of barbed-end actin filament capping biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000814 positive regulation of barbed-end F-actin capping activity|positive regulation of barbed-end actin capping activity|positive regulation of plus-end F-actin capping activity|positive regulation of plus-end actin filament capping activity Any process that activates or increases the frequency, rate or extent of barbed-end actin filament capping. CHEBI:16629 4-amino-2-methyl-5-diphosphooxymethylpyrimidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16629 GO:2000815 regulation of mRNA stability involved in response to oxidative stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000815 A process of regulation of mRNA stability that is involved in a response to oxidative stress. CHEBI:16628 methylguanidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16628 CHEBI:16625 methylmalonyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16625 GO:0075290 regulation of aplanospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075290 Any process that modulates the frequency, rate or extent of aplanospore formation, a process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell. GO:0075291 positive regulation of aplanospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075291 Any process that activates, maintains or increases the frequency, rate or extent of aplanospore formation, a process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell. CHEBI:16624 Leu-tRNA(Leu) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16624 CHEBI:16621 N-phosphotaurocyamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16621 GO:0075292 negative regulation of aplanospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075292 Any process that stops, prevents, or reduces the frequency, rate or extent of aplanospore formation, a process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell. CHEBI:16622 3-dehydro-2-deoxy-D-gluconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16622 GO:0075293 response to host pH environment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075293 response of symbiont to host pH environment Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the pH conditions in or around its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075294 positive regulation by symbiont of entry into host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075294 positive regulation by organism of entry into other organism involved in symbiotic interaction|up regulation by symbiont of entry into host|upregulation by organism of entry into other organism during symbiotic interaction|activation by symbiont of entry into host|activation by organism of entry into other organism during symbiotic interaction|up-regulation by organism of entry into other organism during symbiotic interaction|up-regulation by symbiont of entry into host|positive regulation by organism of entry into other organism during symbiotic interaction|upregulation by symbiont of entry into host|up regulation by organism of entry into other organism during symbiotic interaction Any process that activates or increases the frequency, rate or extent to which it enters into the host organism, where the two organisms are in a symbiotic interaction. GO:0075295 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075295 CHEBI:16620 dTDP-4-dehydro-6-deoxy-D-galactose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16620 GO:0075296 positive regulation of ascospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075296 Any process that activates, maintains or increases the frequency, rate or extent of ascospore formation, a process in which a sexual spore, named ascospore, from Ascomycete fungi was produced inside an ascus. GO:0075297 negative regulation of ascospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075297 Any process that stops, prevents, or reduces the frequency, rate or extent of ascospore formation, a process in which a sexual spore, named ascospore, from Ascomycete fungi was produced inside an ascus. GO:0075298 regulation of zygospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075298 Any process that modulates the frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase. GO:0075299 positive regulation of zygospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075299 Any process that activates, maintains or increases the frequency, rate or extent of frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase. GO:0051236 establishment of RNA localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051236 RNA recruitment|RNA positioning|establishment of RNA localisation The directed movement of RNA to a specific location. GO:0075203 positive regulation of symbiont penetration hypha formation for entry into host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075203 Any process that activates, maintains or increases the frequency, rate or extent of symbiont penetration hypha formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075204 obsolete negative regulation of symbiont penetration hypha formation for entry into host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075204 OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont penetration hypha formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051237 maintenance of RNA location biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051237 RNA retention|maintenance of RNA localization Any process in which RNA is maintained in a location and prevented from moving elsewhere. GO:0051234 establishment of localization biolink:BiologicalProcess go-plus goslim_pir|goslim_flybase_ribbon|goslim_mouse|goslim_agr http://purl.obolibrary.org/obo/GO_0051234 establishment of localisation Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation. GO:0075205 obsolete modulation by host of symbiont cAMP-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075205 modulation by host of symbiont cAMP-mediated signaling|modulation by host of symbiont cAMP-mediated signalling|regulation by host of symbiont cAMP-mediated signaling OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of cAMP-mediated signal transduction in the symbiont. The cAMP-mediated signal transduction is defined as a series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075206 obsolete positive regulation by host of symbiont cAMP-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075206 positive regulation by host of symbiont cAMP-mediated signaling OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of cAMP-mediated signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051235 maintenance of location biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051235 retention|storage|maintenance of localization|sequestering Any process in which a cell, substance or cellular entity, such as a protein complex or organelle, is maintained in a location and prevented from moving elsewhere. GO:0075207 obsolete negative regulation by host of symbiont cAMP-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075207 negative regulation by host of symbiont cAMP-mediated signaling OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of cAMP-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075208 modulation by symbiont of host cAMP-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075208 modulation by symbiont of host cAMP-mediated signaling Any process in which the symbiont modulates the frequency, rate or extent of cAMP-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051238 sequestering of metal ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051238 retention of metal ion|metal ion sequestration|metal ion sequestering|sequestration of metal ion|metal ion retention|storage of metal ion|metal ion storage The process of binding or confining metal ions such that they are separated from other components of a biological system. GO:0075209 induction by symbiont of host cAMP-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075209 positive regulation by symbiont of host cAMP-mediated signaling|positive regulation by symbiont of host cAMP-mediated signal transduction Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of cAMP-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051239 regulation of multicellular organismal process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051239 Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs. GO:2000863 positive regulation of estrogen secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000863 positive regulation of oestrogen secretion Any process that activates or increases the frequency, rate or extent of estrogen secretion. GO:0016907 G protein-coupled acetylcholine receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016907 G protein coupled acetylcholine receptor activity|metabotropic acetylcholine receptor activity|muscarinic acetylcholine receptor activity|acetylcholine receptor activity, G-protein coupled|G-protein coupled acetylcholine receptor activity Combining with acetylcholine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. GO:2000864 regulation of estradiol secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000864 regulation of oestradiol secretion Any process that modulates the frequency, rate or extent of estradiol secretion. GO:0016908 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016908 GO:2000865 negative regulation of estradiol secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000865 negative regulation of oestradiol secretion Any process that stops, prevents or reduces the frequency, rate or extent of estradiol secretion. GO:0016909 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016909 GO:2000866 positive regulation of estradiol secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000866 positive regulation of oestradiol secretion Any process that activates or increases the frequency, rate or extent of estradiol secretion. GO:2000867 regulation of estrone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000867 regulation of 3-hydroxy-1,3,5(10)-estratrien-17-one secretion|regulation of folliculin secretion Any process that modulates the frequency, rate or extent of estrone secretion. GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016903 EC:1.2.-.- oxidoreductase activity, acting on the aldehyde or oxo group of donors, other acceptors Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. GO:2000868 negative regulation of estrone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000868 negative regulation of folliculin secretion|negative regulation of 3-hydroxy-1,3,5(10)-estratrien-17-one secretion Any process that stops, prevents or reduces the frequency, rate or extent of estrone secretion. GO:0016904 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016904 GO:2000869 positive regulation of estrone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000869 positive regulation of folliculin secretion|positive regulation of 3-hydroxy-1,3,5(10)-estratrien-17-one secretion Any process that activates or increases the frequency, rate or extent of estrone secretion. CHEBI:26020 phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26020 GO:0016905 myosin heavy chain kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016905 EC:2.7.11.7|RHEA:11424 ATP:myosin heavy-chain O-phosphotransferase activity|myosin I heavy-chain kinase activity|myosin-heavy-chain kinase activity|STK6|myosin II heavy chain kinase activity|myosin heavy chain kinase A activity|calmodulin-dependent myosin heavy chain kinase activity|ATP:myosin-heavy-chain O-phosphotransferase activity|MHCK|MIHC kinase activity|myosin I heavy chain kinase activity|myosin heavy-chain kinase activity|myosin II heavy-chain kinase activity Catalysis of the reaction: ATP + myosin-heavy-chain = ADP + myosin-heavy-chain phosphate. GO:0016906 sterol 3-beta-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016906 MetaCyc:STEROL-GLUCOSYLTRANSFERASE-RXN|EC:2.4.1.173|RHEA:22724 UDP-glucose-sterol glucosyltransferase activity|UDPglucose:sterol 3-O-beta-D-glucosyltransferase activity|sterol glucosyltransferase activity|sterol-beta-D-glucosyltransferase activity|UDPG-SGTase activity|sterol 3beta-glucosyltransferase activity|sterol:UDPG glucosyltransferase activity|uridine diphosphoglucose-sterol glucosyltransferase activity|uridine diphosphoglucose-poriferasterol glucosyltransferase activity|UDP-glucose-sterol beta-glucosyltransferase activity|UDPG:sterol glucosyltransferase activity|UDP-glucose:sterol 3-O-beta-D-glucosyltransferase activity|UDP-glucose:sterol glucosyltransferase activity Catalysis of the reaction: UDP-glucose + a sterol = UDP + an O-glucosylsterol. GO:1905410 regulation of mitotic cohesin unloading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905410 Any process that modulates the frequency, rate or extent of mitotic cohesin unloading. GO:1905400 negative regulation of activated CD4-positive, alpha-beta T cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905400 downregulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|down regulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|down-regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|downregulation of activated CD4-positive, alpha-beta T cell apoptotic process|negative regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|inhibition of activated CD4-positive, alpha-beta T-cell apoptosis|inhibition of activated CD4-positive, alpha-beta T-cell apoptotic process|negative regulation of activated CD4-positive, alpha-beta T cell apoptosis|down-regulation of activated CD4-positive, alpha-beta T cell apoptosis|downregulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|inhibition of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|inhibition of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|negative regulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|down-regulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|down-regulation of activated CD4-positive, alpha-beta T cell apoptotic process|down regulation of activated CD4-positive, alpha-beta T-cell apoptosis|down-regulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|down regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|downregulation of activated CD4-positive, alpha-beta T-cell apoptosis|negative regulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|down regulation of activated CD4-positive, alpha-beta T-cell apoptotic process|inhibition of activated CD4-positive, alpha-beta T cell apoptosis|inhibition of activated CD4-positive, alpha-beta T cell apoptotic process|downregulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|inhibition of activated CD4-positive, alpha-beta T lymphocyte apoptosis|downregulation of activated CD4-positive, alpha-beta T-cell apoptotic process|inhibition of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|down regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|negative regulation of activated CD4-positive, alpha-beta T-cell apoptosis|down-regulation of activated CD4-positive, alpha-beta T-cell apoptosis|down regulation of activated CD4-positive, alpha-beta T cell apoptosis|downregulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|down-regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|down regulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|negative regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|downregulation of activated CD4-positive, alpha-beta T cell apoptosis|down regulation of activated CD4-positive, alpha-beta T cell apoptotic process|negative regulation of activated CD4-positive, alpha-beta T-cell apoptotic process|down-regulation of activated CD4-positive, alpha-beta T-cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process. GO:1905401 positive regulation of activated CD4-positive, alpha-beta T cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905401 upregulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|up regulation of activated CD4-positive, alpha-beta T cell apoptosis|up-regulation of activated CD4-positive, alpha-beta T-cell apoptosis|positive regulation of activated CD4-positive, alpha-beta T cell apoptosis|up regulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|up-regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|up regulation of activated CD4-positive, alpha-beta T cell apoptotic process|up-regulation of activated CD4-positive, alpha-beta T-cell apoptotic process|positive regulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|activation of activated CD4-positive, alpha-beta T cell apoptosis|activation of activated CD4-positive, alpha-beta T cell apoptotic process|upregulation of activated CD4-positive, alpha-beta T-cell apoptosis|up-regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|up regulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|activation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|activation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|positive regulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|up-regulation of activated CD4-positive, alpha-beta T cell apoptosis|upregulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|upregulation of activated CD4-positive, alpha-beta T-cell apoptotic process|up-regulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|upregulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|up-regulation of activated CD4-positive, alpha-beta T cell apoptotic process|up regulation of activated CD4-positive, alpha-beta T-cell apoptosis|positive regulation of activated CD4-positive, alpha-beta T-cell apoptosis|upregulation of activated CD4-positive, alpha-beta T cell apoptosis|up-regulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|up regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|up regulation of activated CD4-positive, alpha-beta T-cell apoptotic process|positive regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|activation of activated CD4-positive, alpha-beta T-cell apoptosis|activation of activated CD4-positive, alpha-beta T-cell apoptotic process|upregulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|positive regulation of activated CD4-positive, alpha-beta T-cell apoptotic process|upregulation of activated CD4-positive, alpha-beta T cell apoptotic process|up regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|positive regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|activation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|activation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process Any process that activates or increases the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process. GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016900 EC:1.1.4.- oxidoreductase activity, acting on the CH-OH group of donors, disulphide as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces a disulfide molecule. GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016901 EC:1.1.5.- Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule. GO:1905402 regulation of activated CD8-positive, alpha-beta T cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905402 regulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|regulation of activated CD8-positive, alpha-beta T-cell apoptosis|regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|regulation of activated CD8-positive, alpha-beta T-cell apoptotic process|regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|regulation of activated CD8-positive, alpha-beta T cell apoptosis|regulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis Any process that modulates the frequency, rate or extent of activated CD8-positive, alpha-beta T cell apoptotic process. GO:1905403 negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905403 negative regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|down regulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|down-regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|downregulation of activated CD8-positive, alpha-beta T cell apoptotic process|inhibition of activated CD8-positive, alpha-beta T-cell apoptosis|inhibition of activated CD8-positive, alpha-beta T-cell apoptotic process|down-regulation of activated CD8-positive, alpha-beta T cell apoptosis|negative regulation of activated CD8-positive, alpha-beta T cell apoptosis|downregulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|inhibition of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|inhibition of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|negative regulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis|down-regulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis|down-regulation of activated CD8-positive, alpha-beta T cell apoptotic process|down regulation of activated CD8-positive, alpha-beta T-cell apoptosis|negative regulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|down-regulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|downregulation of activated CD8-positive, alpha-beta T-cell apoptosis|down regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|down regulation of activated CD8-positive, alpha-beta T-cell apoptotic process|inhibition of activated CD8-positive, alpha-beta T cell apoptosis|inhibition of activated CD8-positive, alpha-beta T cell apoptotic process|downregulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|downregulation of activated CD8-positive, alpha-beta T-cell apoptotic process|down regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|inhibition of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|inhibition of activated CD8-positive, alpha-beta T lymphocyte apoptosis|down-regulation of activated CD8-positive, alpha-beta T-cell apoptosis|downregulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|down regulation of activated CD8-positive, alpha-beta T cell apoptosis|negative regulation of activated CD8-positive, alpha-beta T-cell apoptosis|down-regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|down regulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis|negative regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|downregulation of activated CD8-positive, alpha-beta T cell apoptosis|negative regulation of activated CD8-positive, alpha-beta T-cell apoptotic process|down regulation of activated CD8-positive, alpha-beta T cell apoptotic process|down-regulation of activated CD8-positive, alpha-beta T-cell apoptotic process|downregulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis Any process that stops, prevents or reduces the frequency, rate or extent of activated CD8-positive, alpha-beta T cell apoptotic process. GO:0016902 obsolete oxidoreductase activity, acting on the CH-OH group of donors, other acceptors biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016902 oxidoreductase activity, acting on the CH-OH group of donors, other acceptors OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces an acceptor other than a cytochrome, disulfide, NAD, NADP, oxygen or a quinone or similar compound. GO:1905404 positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905404 positive regulation of activated CD8-positive, alpha-beta T cell apoptosis|up-regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|up regulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis|up regulation of activated CD8-positive, alpha-beta T cell apoptotic process|positive regulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis|up-regulation of activated CD8-positive, alpha-beta T-cell apoptotic process|activation of activated CD8-positive, alpha-beta T cell apoptosis|activation of activated CD8-positive, alpha-beta T cell apoptotic process|upregulation of activated CD8-positive, alpha-beta T-cell apoptosis|up regulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|up-regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|activation of activated CD8-positive, alpha-beta T lymphocyte apoptosis|activation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|positive regulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|upregulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|up-regulation of activated CD8-positive, alpha-beta T cell apoptosis|upregulation of activated CD8-positive, alpha-beta T-cell apoptotic process|up-regulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis|up-regulation of activated CD8-positive, alpha-beta T cell apoptotic process|upregulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|up regulation of activated CD8-positive, alpha-beta T-cell apoptosis|positive regulation of activated CD8-positive, alpha-beta T-cell apoptosis|upregulation of activated CD8-positive, alpha-beta T cell apoptosis|up regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|up-regulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|up regulation of activated CD8-positive, alpha-beta T-cell apoptotic process|positive regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|activation of activated CD8-positive, alpha-beta T-cell apoptotic process|activation of activated CD8-positive, alpha-beta T-cell apoptosis|upregulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis|positive regulation of activated CD8-positive, alpha-beta T-cell apoptotic process|upregulation of activated CD8-positive, alpha-beta T cell apoptotic process|up regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|activation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|activation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|positive regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|up regulation of activated CD8-positive, alpha-beta T cell apoptosis|upregulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|up-regulation of activated CD8-positive, alpha-beta T-cell apoptosis Any process that activates or increases the frequency, rate or extent of activated CD8-positive, alpha-beta T cell apoptotic process. GO:2000860 positive regulation of aldosterone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000860 Any process that activates or increases the frequency, rate or extent of aldosterone secretion. GO:1905405 regulation of mitotic cohesin loading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905405 Any process that modulates the frequency, rate or extent of mitotic cohesin loading. GO:2000861 regulation of estrogen secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000861 regulation of oestrogen secretion Any process that modulates the frequency, rate or extent of estrogen secretion. CHEBI:16698 cyanamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16698 GO:1905406 positive regulation of mitotic cohesin loading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905406 Any process that activates or increases the frequency, rate or extent of mitotic cohesin loading. GO:1905407 regulation of creatine transmembrane transporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905407 Any process that modulates the frequency, rate or extent of creatine transmembrane transporter activity. GO:2000862 negative regulation of estrogen secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000862 negative regulation of oestrogen secretion Any process that stops, prevents or reduces the frequency, rate or extent of estrogen secretion. CHEBI:16699 2-dehydro-3-deoxy-D-arabinonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16699 GO:1905408 negative regulation of creatine transmembrane transporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905408 down regulation of creatine transmembrane transporter activity|downregulation of creatine transmembrane transporter activity|down-regulation of creatine transmembrane transporter activity|inhibition of creatine transmembrane transporter activity Any process that stops, prevents or reduces the frequency, rate or extent of creatine transmembrane transporter activity. CHEBI:16696 3-methylthiopropylamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16696 GO:1905409 positive regulation of creatine transmembrane transporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905409 upregulation of creatine transmembrane transporter activity|up regulation of creatine transmembrane transporter activity|activation of creatine transmembrane transporter activity|up-regulation of creatine transmembrane transporter activity Any process that activates or increases the frequency, rate or extent of creatine transmembrane transporter activity. CHEBI:16697 indan-1-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16697 CHEBI:16694 5D-(5/6)-2,6-dihydroxy-5-(hydroxymethyl)cyclohex-2-en-1-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16694 CHEBI:16695 uridine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16695 GO:0051232 meiotic spindle elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051232 spindle elongation during meiosis The lengthening of the distance between poles of the spindle during a meiotic cell cycle. CHEBI:16692 diphthamide residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16692 GO:0051233 spindle midzone biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0051233 central spindle|spindle equator The area in the center of the spindle where the spindle microtubules from opposite poles overlap. GO:0075200 obsolete negative regulation of symbiont haustorium neck formation for entry into host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075200 OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont haustorium neck formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:16693 ADP-D-glycero-D-manno-heptose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16693 GO:0075201 penetration hypha formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075201 formation of symbiont penetration hypha for entry into host|symbiont penetration hypha formation for entry into host The assembly by the symbiont of a threadlike, tubular structure, which may contain multiple nuclei and may or may not be divided internally by septa or cross-walls, for the purpose of penetration into its host organism. In the case of an appressorium existing, this term is defined in further details as the process in which the symbiont penetration peg expands to form a hypha which traverses the epidermal cell and emerges into the intercellular space of the mesophyll tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051230 spindle disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051230 spindle degradation|spindle breakdown|spindle catabolism The controlled breakdown of the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart. CHEBI:16690 guanosine 3'-diphosphate 5'-triphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16690 GO:0075202 modulation of symbiont penetration hypha formation for entry into host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075202 Any process that modulates the frequency, rate or extent of symbiont penetration hypha formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051231 spindle elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051231 The cell cycle process in which the distance is lengthened between poles of the spindle. CHEBI:16691 dethiobiotin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16691 GO:0051247 positive regulation of protein metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051247 up regulation of protein metabolic process|activation of protein metabolic process|stimulation of protein metabolic process|up-regulation of protein metabolic process|positive regulation of protein metabolism|upregulation of protein metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein. GO:0051248 negative regulation of protein metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051248 down regulation of protein metabolic process|downregulation of protein metabolic process|down-regulation of protein metabolic process|negative regulation of protein metabolism|inhibition of protein metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein. GO:0051245 negative regulation of cellular defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051245 inhibition of cellular defense response|negative regulation of cellular defence response|down regulation of cellular defense response|downregulation of cellular defense response|down-regulation of cellular defense response Any process that stops, prevents, or reduces the rate of the cellular defense response. GO:0051246 regulation of protein metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051246 regulation of protein metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein. GO:0051249 regulation of lymphocyte activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051249 Any process that modulates the frequency, rate or extent of lymphocyte activation. GO:0016918 retinal binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016918 blue-sensitive opsin|opsin|vitamin A binding|red-sensitive opsin|retinaldehyde binding|short-wave-sensitive opsin|long-wave-sensitive opsin|green-sensitive opsin|UV-sensitive opsin|violet-sensitive opsin Interacting selectively and non-covalently with retinal, one of the forms of vitamin A. Retinal plays an important role in the visual process in most vertebrates, combining with opsins to form visual pigments in the retina. GO:2000874 regulation of glyoxylate cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000874 regulation of glyoxylate bypass Any process that modulates the frequency, rate or extent of glyoxylate cycle. GO:2000875 negative regulation of glyoxylate cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000875 negative regulation of glyoxylate bypass Any process that stops, prevents or reduces the frequency, rate or extent of glyoxylate cycle. GO:0016919 obsolete nardilysin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016919 N-arginine dibasic convertase activity|NRD convertase activity|nardilysin activity|NRD-convertase activity OBSOLETE. Catalysis of the hydrolysis of polypeptides, preferably at the first bond of Xaa-Arg-Lys, and less commonly at the first bond of Arg-Arg-Xaa, in which Xaa is not Arg or Lys. CHEBI:26034 phosphatidylinositol 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26034 GO:2000876 positive regulation of glyoxylate cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000876 positive regulation of glyoxylate bypass Any process that activates or increases the frequency, rate or extent of glyoxylate cycle. GO:2000877 negative regulation of oligopeptide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000877 Any process that stops, prevents or reduces the frequency, rate or extent of oligopeptide transport. CHEBI:26036 phosphatidylinositol monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26036 GO:0016914 follicle-stimulating hormone complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016914 FSH complex|follicle stimulating hormone complex A gonadotrophic glycoprotein hormone secreted, in mammals, by the anterior pituitary gland; consists of alpha and beta subunits, the latter of which confers hormonal specificity. GO:2000878 positive regulation of oligopeptide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000878 Any process that activates or increases the frequency, rate or extent of oligopeptide transport. GO:2000879 negative regulation of dipeptide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000879 Any process that stops, prevents or reduces the frequency, rate or extent of dipeptide transport. GO:0016915 obsolete activin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016915 activin OBSOLETE. A nonsteroidal regulator, composed of two covalently linked beta subunits, that is synthesized in the pituitary gland and gonads and stimulates the secretion of follicle-stimulating hormone. GO:1905420 vascular associated smooth muscle cell differentiation involved in phenotypic switching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905420 vascular smooth muscle cell differentiation involved in phenotypic switching|VSMC differentiation involved in phenotypic switching|vascular associated smooth muscle cell differentiation involved in phenotypic switching|vascular smooth muscle cell differentiation involved in phenotypic dimorphism|vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|VSMC differentiation involved in phenotypic dimorphism Any vascular smooth muscle cell differentiation that is involved in phenotypic switching. GO:0016916 obsolete inhibin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016916 inhibin OBSOLETE. Either of two glycoproteins (designated A and B), secreted by the gonads and present in seminal plasma and follicular fluid, that inhibit pituitary production of follicle-stimulating hormone. GO:0016917 GABA receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016917 gamma-aminobutyrate binding|gamma-aminobutyric acid receptor activity|4-aminobutyrate receptor activity|gamma-aminobutyric acid binding|4-aminobutanoate receptor activity|GABA binding Combining with gamma-aminobutyric acid (GABA), and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. (GABA, 4-aminobutyrate) is an amino acid which acts as a neurotransmitter in some organisms. GO:1905421 regulation of plant organ morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905421 Any process that modulates the frequency, rate or extent of plant organ morphogenesis. GO:0016910 obsolete SAP kinase 3 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016910 SAPK3|SAP kinase 3 activity OBSOLETE. (Was not defined before being made obsolete). GO:1905411 positive regulation of mitotic cohesin unloading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905411 Any process that activates or increases the frequency, rate or extent of mitotic cohesin unloading. GO:0016911 obsolete SAP kinase 4 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016911 SAPK4|SAP kinase 4 activity OBSOLETE. (Was not defined before being made obsolete). GO:1905412 negative regulation of mitotic cohesin loading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905412 Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cohesin loading. GO:1905413 regulation of dense core granule exocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905413 regulation of dense core vesicle exocytosis Any process that modulates the frequency, rate or extent of dense core granule exocytosis. GO:0016912 obsolete SAP kinase 5 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016912 SAPK5|SAP kinase 5 activity OBSOLETE. (Was not defined before being made obsolete). GO:1905414 negative regulation of dense core granule exocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905414 down regulation of dense core granule exocytosis|down regulation of dense core vesicle exocytosis|downregulation of dense core granule exocytosis|downregulation of dense core vesicle exocytosis|down-regulation of dense core granule exocytosis|down-regulation of dense core vesicle exocytosis|negative regulation of dense core vesicle exocytosis|inhibition of dense core granule exocytosis|inhibition of dense core vesicle exocytosis Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule exocytosis. GO:0016913 follicle-stimulating hormone activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016913 FSH activity|follitropin activity|follicle stimulating hormone activity The action characteristic of follicle-stimulating hormone (FSH), a gonadotrophic glycoprotein hormone secreted, in mammals, by the anterior pituitary gland. Upon receptor binding, FSH stimulates growth of Graafian follicles in the ovaries in females, and stimulates the epithelium of the seminiferous tubules to increase spermatogenesis. CHEBI:16689 D-apiose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16689 GO:1905415 positive regulation of dense core granule exocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905415 up regulation of dense core granule exocytosis|up regulation of dense core vesicle exocytosis|activation of dense core granule exocytosis|activation of dense core vesicle exocytosis|positive regulation of dense core vesicle exocytosis|up-regulation of dense core granule exocytosis|up-regulation of dense core vesicle exocytosis|upregulation of dense core granule exocytosis|upregulation of dense core vesicle exocytosis Any process that activates or increases the frequency, rate or extent of dense core granule exocytosis. GO:2000870 regulation of progesterone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000870 Any process that modulates the frequency, rate or extent of progesterone secretion. GO:1905416 regulation of amoeboid sperm motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905416 regulation of ameboid sperm motility|regulation of ameboid sperm movement|regulation of amoeboid sperm movement Any process that modulates the frequency, rate or extent of amoeboid sperm motility. GO:2000871 negative regulation of progesterone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000871 Any process that stops, prevents or reduces the frequency, rate or extent of progesterone secretion. GO:1905417 negative regulation of amoeboid sperm motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905417 downregulation of ameboid sperm motility|negative regulation of ameboid sperm movement|down-regulation of ameboid sperm movement|inhibition of amoeboid sperm motility|down regulation of ameboid sperm motility|inhibition of ameboid sperm motility|negative regulation of amoeboid sperm movement|down-regulation of amoeboid sperm movement|downregulation of ameboid sperm movement|inhibition of amoeboid sperm movement|down regulation of ameboid sperm movement|down regulation of amoeboid sperm motility|inhibition of ameboid sperm movement|downregulation of amoeboid sperm motility|down-regulation of ameboid sperm motility|negative regulation of ameboid sperm motility|down regulation of amoeboid sperm movement|down-regulation of amoeboid sperm motility|downregulation of amoeboid sperm movement Any process that stops, prevents or reduces the frequency, rate or extent of amoeboid sperm motility. GO:2000872 positive regulation of progesterone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000872 Any process that activates or increases the frequency, rate or extent of progesterone secretion. GO:2000873 regulation of histone H4 acetylation involved in response to DNA damage stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000873 regulation of histone H4 acetylation involved in response to DNA damage|regulation of histone H4 acetylation involved in cellular response to DNA damage stimulus|regulation of histone H4 acetylation involved in response to genotoxic stress|regulation of histone H4 acetylation involved in DNA damage response|regulation of histone H4 acetylation involved in cellular DNA damage response Any process that modulates the frequency, rate or extent of histone H4 acetylation involved in response to DNA damage stimulus. GO:1905418 positive regulation of amoeboid sperm motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905418 up regulation of amoeboid sperm movement|positive regulation of amoeboid sperm movement|activation of amoeboid sperm movement|up-regulation of amoeboid sperm motility|positive regulation of ameboid sperm movement|upregulation of ameboid sperm motility|up regulation of ameboid sperm movement|upregulation of amoeboid sperm motility|up-regulation of amoeboid sperm movement|up-regulation of ameboid sperm motility|activation of ameboid sperm motility|upregulation of ameboid sperm movement|up regulation of amoeboid sperm motility|upregulation of amoeboid sperm movement|activation of amoeboid sperm motility|up-regulation of ameboid sperm movement|activation of ameboid sperm movement|positive regulation of ameboid sperm motility|up regulation of ameboid sperm motility Any process that activates or increases the frequency, rate or extent of amoeboid sperm motility. CHEBI:16688 ecdysone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16688 CHEBI:16685 5-(3-carboxy-3-oxopropenyl)-4,6-dihydroxypyridine-2-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16685 GO:1905419 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1905419 GO:0051240 positive regulation of multicellular organismal process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051240 stimulation of multicellular organismal process|up-regulation of multicellular organismal process|activation of multicellular organismal process|up regulation of multicellular organismal process|upregulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. CHEBI:16683 2,3,6-trihydroxypyridine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16683 NCBITaxon:38254 Glaucocystophyceae organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_38254 Glaucophyta|Glaucophyceae|algae|glaucocystophytes CHEBI:16684 atropine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16684 IAO:0000002 example to be eventually removed biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/IAO_0000002 CHEBI:16681 O-sinapoylglucaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16681 GO:0051243 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051243 GO:0051244 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051244 CHEBI:16682 N-acetyl-beta-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16682 GO:0051241 negative regulation of multicellular organismal process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051241 down-regulation of multicellular organismal process|downregulation of multicellular organismal process|down regulation of multicellular organismal process|inhibition of multicellular organismal process Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. CHEBI:16680 S-adenosyl-L-homocysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16680 GO:0051242 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051242 GO:0075225 negative regulation of sporangium germination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075225 negative regulation of sporangium germination on or near host Any process that stops, prevents, or reduces the frequency, rate or extent of sporangium germination. GO:0051258 protein polymerization biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0051258 protein polymer formation|protein polymer biosynthesis|protein polymer biosynthetic process The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein. CHEBI:26008 phenylpyruvate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26008 GO:0075226 encysted zoospore germination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075226 encysted zoospore germination on or near host The physiological, developmental and morphological changes that occur in an encysted zoospore, that germinates by developing a germ tube that may penetrate the host directly or indirectly through an appresorium. An encysted zoospore is a zoospore which has shed its flagellum and whose membrane has fused to form a walled cyst. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051259 protein complex oligomerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051259 protein oligomer assembly|protein oligomerization|protein oligomer biosynthetic process|protein oligomer biosynthesis|protein oligomer formation|protein multimerization The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers; protein oligomers may be composed of different or identical monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer. GO:0051256 mitotic spindle midzone assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051256 spindle midzone formation involved in mitosis|spindle midzone assembly involved in mitosis|mitotic spindle midzone biogenesis|mitotic spindle midzone formation|spindle midzone biogenesis involved in mitosis|mitotic spindle midzone biosynthesis The cell cycle process in which the aggregation, arrangement and bonding together of a set of components forms the spindle midzone. GO:0075227 regulation of encysted zoospore germination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075227 modulation of encysted zoospore germination on or near host|regulation of encysted zoospore germination on or near host Any process that modulates the frequency, rate or extent of an encysted zoospore germination. GO:0051257 meiotic spindle midzone assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051257 meiotic spindle midzone biogenesis|spindle midzone formation involved in meiosis|spindle midzone biosynthesis involved in meiosis|spindle midzone assembly involved in meiosis|meiotic spindle midzone formation|spindle midzone biogenesis involved in meiosis|meiotic spindle midzone biosynthesis The formation of the spindle midzone, the area in the center of the spindle where the spindle microtubules from opposite poles overlap, as a part of the process of meiosis. GO:0075228 positive regulation of encysted zoospore germination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075228 positive regulation of encysted zoospore germination on or near host Any process that activates, maintains or increases the frequency, rate or extent of encysted zoospore germination. GO:0075229 negative regulation of encysted zoospore germination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075229 negative regulation of encysted zoospore germination on or near host Any process that stops, prevents, or reduces the frequency, rate or extent of encysted zoospore germination. CHEBI:26004 phenylpropanoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26004 GO:2000885 galactoglucomannan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000885 galactoglucomannan catabolism The chemical reactions and pathways resulting in the breakdown of a galactoglucomannan. GO:2000886 glucuronoxylan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000886 glucuronoxylan catabolism The chemical reactions and pathways resulting in the breakdown of a glucuronoxylan. GO:2000887 glucuronoarabinoxylan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000887 glucuronoarabinoxylan catabolism The chemical reactions and pathways resulting in the breakdown of a glucuronoarabinoxylan. GO:2000888 arabinoxylan-containing compound catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000888 arabinoxylan catabolism|arabinoxylan catabolic process The chemical reactions and pathways resulting in the breakdown of an arabinoxylan. GO:2000889 cellodextrin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000889 cellodextrin metabolism The chemical reactions and pathways involving a cellodextrin. GO:1905430 cellular response to glycine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905430 cellular response to aminoacetic acid|cellular response to glycin|cellular response to Gly|cellular response to aminoethanoic acid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycine stimulus. GO:1905431 microcystin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905431 The directed movement of a microcystin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:1905432 regulation of retrograde trans-synaptic signaling by neuropeptide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905432 regulation of neuropeptide-mediated retrograde trans-synaptic signaling Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide. GO:1905422 negative regulation of plant organ morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905422 down regulation of plant organ morphogenesis|downregulation of plant organ morphogenesis|down-regulation of plant organ morphogenesis|inhibition of plant organ morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of plant organ morphogenesis. UBERON:0008447 intertarsal joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008447 articulationes intertarsale|intertarsal joint|intertarsal|articulationes intertarsales|articulationes intertarseae|tarsal joints|intertarsal articulation|intermetatarsal joint|tarsal joint Intertarsal articulations are the joints of the tarsus. The specific intertarsal articulations are: Talocalcaneal articulation Talocalcaneonavicular articulation Calcaneocuboid articulation Cuneonavicular articulation Cuboideonavicular articulation Intercuneiform articulation Cuneocuboid articulation GO:1905423 positive regulation of plant organ morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905423 upregulation of plant organ morphogenesis|up regulation of plant organ morphogenesis|activation of plant organ morphogenesis|up-regulation of plant organ morphogenesis Any process that activates or increases the frequency, rate or extent of plant organ morphogenesis. GO:1905424 regulation of Wnt-mediated midbrain dopaminergic neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905424 regulation of Wnt-mediated midbrain DA neuron differentiation|regulation of Wingless signaling pathway involved in mDA neuron differentiation|regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|regulation of Wnt signaling pathway involved in midbrain DA neurogenesis|regulation of Wingless signalling pathway involved in midbrain DA neurogenesis|regulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|regulation of frizzled signaling pathway involved in mDA neuron differentiation|regulation of Wg signalling pathway involved in mDA neuron differentiation|regulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|regulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|regulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|regulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|regulation of Wg signaling pathway involved in mDA neuron differentiation|regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|regulation of frizzled signalling pathway involved in mDA neuron differentiation|regulation of Wingless signaling pathway involved in midbrain DA neurogenesis|regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|regulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|regulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|regulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|regulation of Wnt signaling pathway involved in mDA neuron differentiation|regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|regulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|regulation of Wingless signalling pathway involved in mDA neuron differentiation|regulation of Wg signalling pathway involved in midbrain DA neurogenesis|regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|regulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|regulation of frizzled signaling pathway involved in midbrain DA neurogenesis|regulation of Wg signaling pathway involved in midbrain dopaminergic neuron production|regulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|regulation of Wnt receptor signaling pathway involved in mDA neuron differentiation|regulation of Wnt receptor signalling pathway involved in mDA neuron differentiation|regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation|regulation of midbrain dopaminergic neuron differentiation by regulation of Wnt signaling|regulation of Wg signalling pathway involved in midbrain dopaminergic neuron production|regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|regulation of Wg signaling pathway involved in midbrain DA neurogenesis|regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|regulation of frizzled signalling pathway involved in midbrain DA neurogenesis|regulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|regulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate Any process that modulates the frequency, rate or extent of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation. GO:1905425 negative regulation of Wnt-mediated midbrain dopaminergic neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905425 down-regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|inhibition of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of Wg signaling pathway involved in midbrain dopaminergic neuron production|negative regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|downregulation of Wg signaling pathway involved in midbrain DA neurogenesis|down-regulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wg signalling pathway involved in midbrain dopaminergic neuron production|inhibition of Wg signaling pathway involved in mDA neuron differentiation|down regulation of Wingless signaling pathway involved in mDA neuron differentiation|down regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wg signalling pathway involved in midbrain DA neurogenesis|down regulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of frizzled signalling pathway involved in midbrain DA neurogenesis|negative regulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|down regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation|down-regulation of Wg signalling pathway involved in mDA neuron differentiation|down regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|negative regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of Wnt receptor signalling pathway involved in mDA neuron differentiation|down-regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of Wg signalling pathway involved in mDA neuron differentiation|down-regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of frizzled signalling pathway involved in midbrain DA neurogenesis|down-regulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|negative regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|inhibition of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wnt-mediated midbrain DA neuron differentiation|downregulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of frizzled signaling pathway involved in midbrain dopaminergic neuron production|negative regulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|down-regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|downregulation of Wnt signaling pathway involved in midbrain DA neurogenesis|negative regulation of frizzled signalling pathway involved in mDA neuron differentiation|down-regulation of frizzled signalling pathway involved in mDA neuron differentiation|negative regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|inhibition of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wingless signaling pathway involved in mDA neuron differentiation|inhibition of Wingless signaling pathway involved in midbrain DA neurogenesis|inhibition of Wingless signalling pathway involved in midbrain dopaminergic neuron production|downregulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|down regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wingless signalling pathway involved in midbrain DA neurogenesis|down regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|negative regulation of frizzled signaling pathway involved in midbrain DA neurogenesis|negative regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|down regulation of Wnt signaling pathway involved in midbrain DA neurogenesis|inhibition of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wnt signaling pathway involved in midbrain dopaminergic neuron production|down-regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of Wnt-activated signaling pathway involved in mDA neuron differentiation|down-regulation of frizzled signaling pathway involved in midbrain DA neurogenesis|negative regulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of Wnt receptor signaling pathway involved in mDA neuron differentiation|down-regulation of Wnt receptor signaling pathway involved in mDA neuron differentiation|down-regulation of Wg signalling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of Wg signalling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wg signaling pathway involved in midbrain DA neurogenesis|negative regulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of Wg signaling pathway involved in midbrain DA neurogenesis|inhibition of Wnt signaling pathway involved in midbrain DA neurogenesis|down-regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wg signalling pathway involved in mDA neuron differentiation|down regulation of Wingless signalling pathway involved in midbrain DA neurogenesis|negative regulation of Wnt signaling pathway involved in mDA neuron differentiation|down regulation of frizzled signaling pathway involved in mDA neuron differentiation|downregulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|down regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wnt signaling pathway involved in mDA neuron differentiation|down regulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|negative regulation of Wnt-mediated midbrain DA neuron differentiation|down regulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|down regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wnt-mediated midbrain DA neuron differentiation|downregulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|down regulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of Wingless signaling pathway involved in midbrain dopaminergic neuron production|downregulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|downregulation of frizzled signalling pathway involved in mDA neuron differentiation|inhibition of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of Wingless signalling pathway involved in midbrain DA neurogenesis|down regulation of Wg signaling pathway involved in mDA neuron differentiation|inhibition of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of Wingless signalling pathway involved in mDA neuron differentiation|negative regulation of Wingless signaling pathway involved in mDA neuron differentiation|negative regulation of Wingless signalling pathway involved in mDA neuron differentiation|inhibition of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|down-regulation of Wingless signaling pathway involved in mDA neuron differentiation|inhibition of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|inhibition of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of frizzled signaling pathway involved in midbrain DA neurogenesis|inhibition of frizzled signalling pathway involved in midbrain dopaminergic neuron production|down regulation of Wg signalling pathway involved in mDA neuron differentiation|downregulation of frizzled signaling pathway involved in mDA neuron differentiation|downregulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|inhibition of Wnt receptor signaling pathway involved in mDA neuron differentiation|downregulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|down regulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|down regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|down regulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of frizzled signalling pathway involved in mDA neuron differentiation|inhibition of Wg signalling pathway involved in mDA neuron differentiation|inhibition of Wg signalling pathway involved in midbrain dopaminergic neuron production|inhibition of Wg signaling pathway involved in midbrain DA neurogenesis|downregulation of Wg signaling pathway involved in mDA neuron differentiation|inhibition of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|downregulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|down regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|down regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|down regulation of Wingless signaling pathway involved in midbrain DA neurogenesis|down-regulation of Wg signaling pathway involved in midbrain dopaminergic neuron production|negative regulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of Wg signaling pathway involved in midbrain dopaminergic neuron production|negative regulation of Wg signalling pathway involved in midbrain DA neurogenesis|inhibition of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|inhibition of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|down-regulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of Wg signalling pathway involved in midbrain DA neurogenesis|inhibition of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of Wnt receptor signalling pathway involved in mDA neuron differentiation|downregulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wnt-mediated midbrain DA neuron differentiation|down regulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of frizzled signalling pathway involved in mDA neuron differentiation|down-regulation of Wnt receptor signalling pathway involved in mDA neuron differentiation|down regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of frizzled signalling pathway involved in midbrain DA neurogenesis|negative regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|down-regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation|down-regulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation|down regulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|down-regulation of frizzled signalling pathway involved in midbrain DA neurogenesis|downregulation of Wnt signaling pathway involved in mDA neuron differentiation|negative regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|down regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|downregulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wingless signaling pathway involved in midbrain DA neurogenesis|downregulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wingless signaling pathway involved in mDA neuron differentiation|down regulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|down regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|inhibition of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wingless signalling pathway involved in mDA neuron differentiation|negative regulation of midbrain dopaminergic neuron differentiation by negative regulation of Wnt signaling|downregulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|down regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|down regulation of Wnt signaling pathway involved in mDA neuron differentiation|negative regulation of frizzled signaling pathway involved in mDA neuron differentiation|down-regulation of frizzled signaling pathway involved in mDA neuron differentiation|inhibition of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|negative regulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|negative regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|negative regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wnt signaling pathway involved in mDA neuron differentiation|negative regulation of Wg signaling pathway involved in mDA neuron differentiation|down-regulation of Wg signaling pathway involved in mDA neuron differentiation|down-regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wg signaling pathway involved in midbrain dopaminergic neuron production|down regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|down regulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wg signalling pathway involved in midbrain DA neurogenesis|down regulation of frizzled signaling pathway involved in midbrain DA neurogenesis|downregulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of Wnt signaling pathway involved in midbrain DA neurogenesis|inhibition of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|down regulation of Wingless signalling pathway involved in mDA neuron differentiation|negative regulation of Wnt signaling pathway involved in midbrain DA neurogenesis|down regulation of Wnt receptor signaling pathway involved in mDA neuron differentiation|downregulation of Wnt receptor signalling pathway involved in mDA neuron differentiation|down regulation of Wg signalling pathway involved in midbrain dopaminergic neuron production|downregulation of frizzled signalling pathway involved in midbrain DA neurogenesis|downregulation of Wnt-activated signaling pathway involved in mDA neuron differentiation|down regulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wingless signalling pathway involved in mDA neuron differentiation|downregulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|down regulation of Wg signaling pathway involved in midbrain DA neurogenesis|down-regulation of Wingless signalling pathway involved in midbrain DA neurogenesis|down-regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|negative regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|down-regulation of Wingless signaling pathway involved in midbrain DA neurogenesis|negative regulation of Wingless signalling pathway involved in midbrain DA neurogenesis|down-regulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of Wingless signaling pathway involved in midbrain DA neurogenesis|down-regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|negative regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|down regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|down-regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of Wg signaling pathway involved in midbrain dopaminergic neuron production|downregulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|down regulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of Wg signalling pathway involved in midbrain DA neurogenesis|inhibition of frizzled signaling pathway involved in mDA neuron differentiation|downregulation of frizzled signaling pathway involved in midbrain DA neurogenesis|down regulation of Wnt-mediated midbrain DA neuron differentiation|inhibition of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|down regulation of Wnt receptor signalling pathway involved in mDA neuron differentiation|downregulation of Wnt receptor signaling pathway involved in mDA neuron differentiation|inhibition of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production Any process that stops, prevents or reduces the frequency, rate or extent of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation. GO:2000880 positive regulation of dipeptide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000880 Any process that activates or increases the frequency, rate or extent of dipeptide transport. GO:1905426 positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905426 up-regulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|up-regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|up regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|up-regulation of Wg signaling pathway involved in mDA neuron differentiation|up-regulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|upregulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of Wnt signaling pathway involved in midbrain DA neurogenesis|positive regulation of Wingless signalling pathway involved in midbrain DA neurogenesis|upregulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|up regulation of frizzled signaling pathway involved in midbrain DA neurogenesis|upregulation of Wg signalling pathway involved in midbrain DA neurogenesis|up regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|positive regulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|upregulation of Wg signaling pathway involved in midbrain dopaminergic neuron production|up regulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|activation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|activation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|up-regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|activation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|activation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|up regulation of Wnt receptor signaling pathway involved in mDA neuron differentiation|upregulation of Wnt receptor signalling pathway involved in mDA neuron differentiation|activation of frizzled signaling pathway involved in midbrain DA neurogenesis|activation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|up regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|upregulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|upregulation of Wnt-activated signaling pathway involved in mDA neuron differentiation|up regulation of Wingless signalling pathway involved in midbrain DA neurogenesis|up regulation of Wg signalling pathway involved in midbrain dopaminergic neuron production|activation of Wnt receptor signaling pathway involved in mDA neuron differentiation|upregulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|positive regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|upregulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wnt signaling pathway involved in mDA neuron differentiation|up regulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of frizzled signaling pathway involved in midbrain DA neurogenesis|up regulation of Wg signaling pathway involved in midbrain DA neurogenesis|positive regulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wnt signaling pathway involved in mDA neuron differentiation|upregulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|up regulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|upregulation of frizzled signalling pathway involved in midbrain DA neurogenesis|activation of Wg signaling pathway involved in midbrain DA neurogenesis|positive regulation of Wnt receptor signaling pathway involved in mDA neuron differentiation|up-regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|activation of Wg signalling pathway involved in midbrain dopaminergic neuron production|activation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|up-regulation of Wingless signaling pathway involved in midbrain DA neurogenesis|up regulation of Wnt-mediated midbrain DA neuron differentiation|positive regulation of Wg signalling pathway involved in midbrain dopaminergic neuron production|positive regulation of Wg signalling pathway involved in mDA neuron differentiation|positive regulation of Wg signaling pathway involved in midbrain DA neurogenesis|positive regulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wingless signalling pathway involved in mDA neuron differentiation|positive regulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|up-regulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|positive regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|positive regulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|activation of Wnt-mediated midbrain DA neuron differentiation|activation of Wingless signalling pathway involved in mDA neuron differentiation|positive regulation of frizzled signalling pathway involved in mDA neuron differentiation|up regulation of Wingless signaling pathway involved in mDA neuron differentiation|up-regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|positive regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|positive regulation of Wnt-mediated midbrain DA neuron differentiation|up-regulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|up regulation of Wg signalling pathway involved in mDA neuron differentiation|upregulation of frizzled signaling pathway involved in mDA neuron differentiation|activation of Wingless signaling pathway involved in mDA neuron differentiation|upregulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|up regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|upregulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|up-regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|upregulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|up regulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|upregulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|up regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|positive regulation of Wingless signaling pathway involved in mDA neuron differentiation|activation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of frizzled signalling pathway involved in mDA neuron differentiation|upregulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|upregulation of Wg signaling pathway involved in mDA neuron differentiation|up-regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wg signaling pathway involved in midbrain dopaminergic neuron production|activation of Wg signalling pathway involved in midbrain DA neurogenesis|activation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wg signaling pathway involved in midbrain dopaminergic neuron production|up-regulation of Wg signalling pathway involved in midbrain DA neurogenesis|up-regulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|upregulation of Wnt signaling pathway involved in midbrain DA neurogenesis|up-regulation of Wnt receptor signalling pathway involved in mDA neuron differentiation|positive regulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wnt receptor signalling pathway involved in mDA neuron differentiation|up-regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|up-regulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|activation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|activation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|up-regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|activation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation|up-regulation of frizzled signalling pathway involved in midbrain DA neurogenesis|activation of frizzled signalling pathway involved in midbrain DA neurogenesis|upregulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|upregulation of Wingless signalling pathway involved in midbrain DA neurogenesis|upregulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|upregulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|upregulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|upregulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|upregulation of Wingless signaling pathway involved in midbrain DA neurogenesis|positive regulation of Wnt signaling pathway involved in mDA neuron differentiation|up-regulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|activation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|up-regulation of frizzled signaling pathway involved in midbrain DA neurogenesis|upregulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|positive regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|up-regulation of Wnt receptor signaling pathway involved in mDA neuron differentiation|upregulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wg signalling pathway involved in midbrain dopaminergic neuron production|upregulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|up-regulation of Wg signaling pathway involved in midbrain DA neurogenesis|up regulation of Wnt signaling pathway involved in mDA neuron differentiation|up-regulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|upregulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|upregulation of Wg signalling pathway involved in mDA neuron differentiation|activation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of frizzled signaling pathway involved in mDA neuron differentiation|positive regulation of Wingless signalling pathway involved in mDA neuron differentiation|upregulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|up regulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|upregulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|activation of Wnt-activated signaling pathway involved in mDA neuron differentiation|activation of frizzled signaling pathway involved in mDA neuron differentiation|upregulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|up regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|up regulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|up-regulation of Wnt-mediated midbrain DA neuron differentiation|upregulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|up-regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|activation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|upregulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|up-regulation of Wnt signaling pathway involved in midbrain DA neurogenesis|activation of Wnt signaling pathway involved in midbrain DA neurogenesis|positive regulation of frizzled signaling pathway involved in mDA neuron differentiation|upregulation of frizzled signalling pathway involved in mDA neuron differentiation|activation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|up regulation of Wg signaling pathway involved in mDA neuron differentiation|up regulation of Wingless signalling pathway involved in mDA neuron differentiation|positive regulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|up-regulation of Wingless signaling pathway involved in mDA neuron differentiation|activation of Wg signaling pathway involved in mDA neuron differentiation|positive regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|up-regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|positive regulation of Wg signaling pathway involved in mDA neuron differentiation|positive regulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of Wg signalling pathway involved in midbrain DA neurogenesis|positive regulation of Wg signaling pathway involved in midbrain dopaminergic neuron production|positive regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|activation of Wingless signalling pathway involved in midbrain DA neurogenesis|up-regulation of Wingless signalling pathway involved in midbrain DA neurogenesis|positive regulation of Wnt receptor signalling pathway involved in mDA neuron differentiation|up regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|positive regulation of midbrain dopaminergic neuron differentiation by positive regulation of Wnt signaling|up-regulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|positive regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation|upregulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|upregulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|up regulation of Wg signaling pathway involved in midbrain dopaminergic neuron production|up regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of Wg signalling pathway involved in midbrain DA neurogenesis|upregulation of frizzled signaling pathway involved in midbrain DA neurogenesis|positive regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of Wingless signaling pathway involved in midbrain DA neurogenesis|up regulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of frizzled signalling pathway involved in midbrain DA neurogenesis|positive regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|upregulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|up regulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|activation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|up regulation of Wnt receptor signalling pathway involved in mDA neuron differentiation|activation of Wingless signaling pathway involved in midbrain DA neurogenesis|activation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|activation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|upregulation of Wnt receptor signaling pathway involved in mDA neuron differentiation|upregulation of Wg signaling pathway involved in midbrain DA neurogenesis|upregulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|upregulation of Wg signalling pathway involved in midbrain dopaminergic neuron production|up regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation|positive regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|up regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|positive regulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|upregulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of Wingless signaling pathway involved in midbrain DA neurogenesis|up regulation of frizzled signalling pathway involved in midbrain DA neurogenesis|up regulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|up-regulation of Wg signalling pathway involved in mDA neuron differentiation|up regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|activation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|up-regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wg signalling pathway involved in mDA neuron differentiation|up regulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|upregulation of Wnt signaling pathway involved in mDA neuron differentiation|up-regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|positive regulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|activation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|activation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|activation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|activation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|upregulation of Wnt-mediated midbrain DA neuron differentiation|up regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|activation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|activation of frizzled signalling pathway involved in mDA neuron differentiation|positive regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|positive regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|up-regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|up-regulation of frizzled signalling pathway involved in mDA neuron differentiation|upregulation of Wingless signalling pathway involved in mDA neuron differentiation|positive regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|positive regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|upregulation of Wingless signaling pathway involved in mDA neuron differentiation|upregulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|positive regulation of Wnt signaling pathway involved in midbrain DA neurogenesis|up-regulation of frizzled signaling pathway involved in mDA neuron differentiation Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation. GO:2000881 regulation of starch catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000881 regulation of starch breakdown|regulation of starch catabolism|regulation of starch degradation Any process that modulates the frequency, rate or extent of starch catabolic process. GO:1905427 intracellular signal transduction involved in positive regulation of cell growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905427 intracellular signaling chain involved in upregulation of cell growth|protein kinase cascade involved in stimulation of cell growth|intracellular signaling cascade involved in activation of cell growth|intracellular protein kinase cascade involved in activation of cell growth|intracellular signaling pathway involved in stimulation of cell growth|intracellular signaling cascade involved in up regulation of cell growth|protein kinase cascade involved in up-regulation of cell growth|intracellular signal transduction involved in upregulation of cell growth|intracellular signaling cascade involved in positive regulation of cell growth|intracellular signal transduction involved in up regulation of cell growth|intracellular signaling pathway involved in up-regulation of cell growth|intracellular signal transduction pathway involved in activation of cell growth|signal transduction via intracellular signaling cascade involved in up regulation of cell growth|signal transmission via intracellular cascade involved in activation of cell growth|protein kinase cascade involved in upregulation of cell growth|signal transmission via intracellular cascade involved in up regulation of cell growth|signal transduction via intracellular signaling cascade involved in positive regulation of cell growth|signal transmission via intracellular cascade involved in positive regulation of cell growth|intracellular signaling chain involved in activation of cell growth|intracellular signaling chain involved in up regulation of cell growth|intracellular signal transduction pathway involved in up regulation of cell growth|intracellular signal transduction involved in stimulation of cell growth|intracellular signaling pathway involved in activation of cell growth|intracellular signal transduction pathway involved in positive regulation of cell growth|signal transduction via intracellular signaling cascade involved in upregulation of cell growth|intracellular signaling cascade involved in stimulation of cell growth|intracellular signaling chain involved in positive regulation of cell growth|intracellular protein kinase cascade involved in up regulation of cell growth|intracellular signaling cascade involved in up-regulation of cell growth|intracellular signal transduction involved in activation of cell growth|intracellular signaling chain involved in stimulation of cell growth|signal transduction via intracellular signaling cascade involved in stimulation of cell growth|intracellular signaling cascade involved in upregulation of cell growth|intracellular protein kinase cascade involved in positive regulation of cell growth|intracellular protein kinase cascade involved in upregulation of cell growth|intracellular signal transduction involved in up-regulation of cell growth|signal transmission via intracellular cascade involved in stimulation of cell growth|signal transduction via intracellular signaling cascade involved in up-regulation of cell growth|intracellular signal transduction pathway involved in stimulation of cell growth|intracellular signal transduction pathway involved in upregulation of cell growth|signal transmission via intracellular cascade involved in up-regulation of cell growth|protein kinase cascade involved in up regulation of cell growth|signal transmission via intracellular cascade involved in upregulation of cell growth|intracellular signaling chain involved in up-regulation of cell growth|intracellular signal transduction pathway involved in up-regulation of cell growth|intracellular signaling pathway involved in up regulation of cell growth|protein kinase cascade involved in positive regulation of cell growth|intracellular protein kinase cascade involved in stimulation of cell growth|protein kinase cascade involved in activation of cell growth|intracellular signaling pathway involved in upregulation of cell growth|intracellular signaling pathway involved in positive regulation of cell growth|intracellular protein kinase cascade involved in up-regulation of cell growth|signal transduction via intracellular signaling cascade involved in activation of cell growth Any intracellular signal transduction that is involved in positive regulation of cell growth. GO:2000882 negative regulation of starch catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000882 negative regulation of starch degradation|negative regulation of starch catabolism|negative regulation of starch breakdown Any process that stops, prevents or reduces the frequency, rate or extent of starch catabolic process. GO:2000883 positive regulation of starch catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000883 positive regulation of starch catabolism|positive regulation of starch degradation|positive regulation of starch breakdown Any process that activates or increases the frequency, rate or extent of starch catabolic process. GO:1905428 regulation of plant organ formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905428 Any process that modulates the frequency, rate or extent of plant organ formation. GO:1905429 response to glycine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905429 response to aminoethanoic acid|response to glycin|response to aminoacetic acid|response to Gly Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycine stimulus. GO:2000884 glucomannan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000884 glucomannan catabolism The chemical reactions and pathways resulting in the breakdown of a glucomannan. GO:0051250 negative regulation of lymphocyte activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051250 down-regulation of lymphocyte activation|inhibition of lymphocyte activation|down regulation of lymphocyte activation|downregulation of lymphocyte activation Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte activation. GO:0051251 positive regulation of lymphocyte activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051251 up regulation of lymphocyte activation|activation of lymphocyte activation|stimulation of lymphocyte activation|up-regulation of lymphocyte activation|upregulation of lymphocyte activation Any process that activates or increases the frequency, rate or extent of lymphocyte activation. GO:0075220 positive regulation of zoospore encystment on host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075220 Any process that activates, maintains or increases the frequency, rate or extent of zoospore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051254 positive regulation of RNA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051254 up-regulation of RNA metabolic process|positive regulation of RNA metabolism|upregulation of RNA metabolic process|up regulation of RNA metabolic process|activation of RNA metabolic process|stimulation of RNA metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA. GO:0075221 negative regulation of zoospore encystment on host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075221 Any process that stops, prevents, or reduces the frequency, rate or extent of zoospore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075222 sporangium germination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075222 direct germination on or near host|germination of symbiont sporangium on or near host|sporangium germination on or near host|symbiont sporangium germination on or near host The physiological, developmental and morphological changes that occur in a symbiont sporangium following release from dormancy up to the earliest signs of growth. A sporangium is a structure producing and containing spores. GO:0051255 spindle midzone assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051255 spindle midzone formation|spindle midzone biosynthesis|spindle midzone biogenesis The cell cycle process in which aggregation, arrangement and bonding together of a set of components to form the spindle midzone. The spindle midzone is the area in the center of the spindle where the spindle microtubules from opposite poles overlap. GO:0075223 regulation of sporangium germination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075223 modulation of sporangium germination on or near host|modulation of sporangium germination Any process that modulates the frequency, rate or extent of sporangium germination. GO:0051252 regulation of RNA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051252 regulation of RNA metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA. GO:0051253 negative regulation of RNA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051253 inhibition of RNA metabolic process|negative regulation of RNA metabolism|down regulation of RNA metabolic process|downregulation of RNA metabolic process|down-regulation of RNA metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA. GO:0075224 positive regulation of sporangium germination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075224 positive regulation of sporangium germination on or near host Any process that activates, maintains or increases the frequency, rate or extent of sporangium germination. GO:0075214 spore encystment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075214 spore encystment on host The physiological, developmental and morphological changes that occur in a symbiont spore during the process of its encystment. Encystment means to enter a state of essentially suspended animation in which the spore is protected by an outer coating and remains immobile and inactive until favorable conditions for growth occur again. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051269 alpha-keto ester reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051269 EC:1.2.-.- Catalysis of the reaction: alpha-keto ester + 2 H+ (from donor) = (R)-hydroxy ester. Alpha-keto esters are of the form R(1)-CO-CO-O-R(2), where the R groups may be aromatic or aliphatic. GO:0075215 modulation of spore encystment on host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075215 Any process that modulates the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051267 CP2 mannose-ethanolamine phosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051267 gpi7 activity|addition of ethanolamine phosphate to mannose of GPI precursor CP2|CP2 EtN-P transferase activity|CP2 ethanolamine phosphate transferase activity|CP2 phosphoethanolamine transferase activity Catalysis of the reaction: ethanolamine phosphate + Man-alpha-(1,2)-Man-alpha-(1,2)-Man-alpha-(1,6)-R = Man-alpha-(1,2)-Man-alpha-6-P-EtN-(1,2)-Man-alpha-(1,6)-R; R is Man-alpha(1,4)-GlcNH2-inositol-PO4-lipid. This reaction is the transfer of ethanolamine phosphate to C6 of second mannose in the GPI lipid precursor CP2. GO:0075216 positive regulation of spore encystment on host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075216 Any process that activates, maintains or increases the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075217 negative regulation of spore encystment on host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075217 Any process that stops, prevents, or reduces the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051268 alpha-keto amide reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051268 Catalysis of the reaction: alpha-keto amide + 2 H+ (from donor) = (R)-hydroxy amide. Alpha-keto amides are of the form R-CO-CONH2, where R may be aromatic or aliphatic. GO:0075218 zoospore encystment on host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075218 The physiological, developmental and morphological changes that occur in a symbiont zoospore during the process of its encystment. Encystment means to enter a state of essentially suspended animation in which the spore is protected by an outer coating and remains immobile and inactive until favorable conditions for growth occur again. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075219 modulation of zoospore encystment on host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075219 Any process that modulates the frequency, rate or extent of zoospore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:2000896 amylopectin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000896 Amylopectin metabolism The chemical reactions and pathways involving an amylopectin. CHEBI:41630 S-oxy-L-cysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_41630 GO:2000897 amylopectin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000897 Amylopectin catabolism The chemical reactions and pathways resulting in the breakdown of an amylopectin. GO:2000898 regulation of glucomannan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000898 regulation of glucomannan catabolism Any process that modulates the frequency, rate or extent of glucomannan catabolic process. CHEBI:26013 pheromone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_26013 GO:2000899 xyloglucan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000899 xyloglucan catabolism The chemical reactions and pathways resulting in the breakdown of a xyloglucan. GO:1905440 cellular response to chondroitin 6'-sulfate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905440 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 6'-sulfate stimulus. GO:1905441 response to chondroitin 4'-sulfate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905441 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 4'-sulfate stimulus. GO:1905442 cellular response to chondroitin 4'-sulfate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905442 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 4'-sulfate stimulus. GO:1905443 regulation of clathrin coat assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905443 regulation of clathrin cage assembly Any process that modulates the frequency, rate or extent of clathrin coat assembly. GO:1905433 negative regulation of retrograde trans-synaptic signaling by neuropeptide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905433 down-regulation of retrograde trans-synaptic signaling by neuropeptide|negative regulation of neuropeptide-mediated retrograde trans-synaptic signaling|inhibition of retrograde trans-synaptic signaling by neuropeptide|inhibition of neuropeptide-mediated retrograde trans-synaptic signaling|down regulation of retrograde trans-synaptic signaling by neuropeptide|downregulation of retrograde trans-synaptic signaling by neuropeptide Any process that stops, prevents or reduces the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide. GO:1905434 positive regulation of retrograde trans-synaptic signaling by neuropeptide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905434 up regulation of retrograde trans-synaptic signaling by neuropeptide|activation of retrograde trans-synaptic signaling by neuropeptide|positive regulation of neuropeptide-mediated retrograde trans-synaptic signaling|up-regulation of retrograde trans-synaptic signaling by neuropeptide|upregulation of retrograde trans-synaptic signaling by neuropeptide Any process that activates or increases the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide. UBERON:0008436 thoracic vertebral arch biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008436 arch of thoracic vertebra A neural arch that is part of a thoracic vertebra. GO:1905435 regulation of histone H3-K4 trimethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905435 Any process that modulates the frequency, rate or extent of histone H3-K4 trimethylation. GO:2000890 cellodextrin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000890 cellodextrin catabolism The chemical reactions and pathways resulting in the breakdown of a cellodextrin. GO:2000891 cellobiose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000891 cellobiose metabolism The chemical reactions and pathways involving a cellobiose. GO:1905436 negative regulation of histone H3-K4 trimethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905436 down-regulation of histone H3-K4 trimethylation|downregulation of histone H3-K4 trimethylation|down regulation of histone H3-K4 trimethylation|inhibition of histone H3-K4 trimethylation Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K4 trimethylation. GO:1905437 positive regulation of histone H3-K4 trimethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905437 up-regulation of histone H3-K4 trimethylation|activation of histone H3-K4 trimethylation|up regulation of histone H3-K4 trimethylation|upregulation of histone H3-K4 trimethylation Any process that activates or increases the frequency, rate or extent of histone H3-K4 trimethylation. GO:2000892 cellobiose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000892 cellobiose catabolism The chemical reactions and pathways resulting in the breakdown of a cellobiose. GO:1905438 non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905438 non-canonical Wnt-activated signaling pathway involved in midbrain DA neurogenesis|non-canonical Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|non-canonical Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|beta-catenin-independent Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|non-canonical Wnt receptor signalling pathway involved in midbrain DA neurogenesis|beta-catenin-independent Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|beta-catenin-independent Wnt receptor signaling pathway involved in mDA neuron differentiation|non-canonical Wnt receptor signaling pathway involved in mDA neuron differentiation|non-canonical Wnt signaling pathway involved in mDA neuron differentiation|non-canonical Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|beta-catenin-independent Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|non-canonical Wnt-activated signaling pathway involved in mDA neuron differentiation|non-canonical Wnt receptor signalling pathway involved in mDA neuron differentiation|non-canonical Wnt receptor signaling pathway involved in midbrain DA neurogenesis|non-canonical Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|beta-catenin-independent Wnt receptor signaling pathway involved in midbrain DA neurogenesis|non-canonical Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|non-canonical Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|non-canonical Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|non-canonical Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|non-canonical Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|non-canonical Wnt signaling pathway involved in midbrain DA neurogenesis|non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron production|non-canonical Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate Any non-canonical Wnt signaling pathway that is involved in midbrain dopaminergic neuron differentiation. GO:2000893 cellotriose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000893 cellotriose metabolism The chemical reactions and pathways involving a cellotriose. GO:2000894 cellotriose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000894 cellotriose catabolism The chemical reactions and pathways resulting in the breakdown of a cellotriose. GO:1905439 response to chondroitin 6'-sulfate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905439 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 6'-sulfate stimulus. CHEBI:41633 24(S),25-epoxycholesterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_41633 GO:2000895 hemicellulose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000895 hemicellulose catabolism The chemical reactions and pathways resulting in the breakdown of a hemicellulose. GO:0051261 protein depolymerization biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0051261 protein polymer catabolic process|protein polymer catabolism|protein polymer degradation|protein polymer breakdown The process in which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein. GO:0051262 protein tetramerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051262 protein tetramer biosynthesis|protein tetramer biosynthetic process|protein tetramer assembly|protein tetramer formation The formation of a protein tetramer, a macromolecular structure consisting of four noncovalently associated identical or nonidentical subunits. GO:0051260 protein homooligomerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051260 protein homooligomer biosynthetic process|protein homooligomer biosynthesis|protein homooligomer formation|protein homooligomer assembly|protein homooligomerization activity The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer. GO:0051265 diolein transacylation activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051265 dioleoylglycerol transacylase activity|acyl-CoA-independent diolein transacylation|dioleoylglycerol O-acyltransferase activity|DOG transacylation Catalysis of the reaction: diolein + mono-olein = triolein + glycerol. Mono-olein, also known as mono-oleoylglycerol, is the monoglyceride formed from oleic acid, 9-octodecenoic acid; diolein is also known as dioleoylglycerol, and triolein as trioleoylglycerol and olein. GO:0075210 suppression by symbiont of host cAMP-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075210 negative regulation by symbiont of host cAMP-mediated signaling|negative regulation by symbiont of host cAMP-mediated signal transduction Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of cAMP-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051266 sirohydrochlorin ferrochelatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051266 KEGG_REACTION:R02864|RHEA:24360|EC:4.99.1.4|MetaCyc:SIROHEME-FERROCHELAT-RXN Met8P|siroheme ferro-lyase (sirohydrochlorin-forming)|CysG|siroheme synthase activity|SirB|sirohydrochlorin ferro-lyase activity Catalysis of the reaction: siroheme + 2 H+ = Fe(2+) + sirohydrochlorin. GO:0075211 obsolete regulation of transmembrane receptor-mediated cAMP signaling in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075211 regulation of transmembrane receptor-mediated cAMP signal transduction in response to host|regulation of transmembrane receptor-mediated cAMP signalling in response to host|regulation of symbiont transmembrane receptor-mediated cAMP signal transduction in response to host OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its transmembrane receptor-mediated cAMP signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. UBERON:0008432 thoracic vertebral foramen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008432 A vertebral foramen that is part of a thoracic vertebra. GO:0075212 obsolete positive regulation of transmembrane receptor-mediated cAMP signal transduction in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075212 positive regulation of symbiont transmembrane receptor-mediated cAMP signal transduction in response to host OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its transmembrane receptor-mediated cAMP signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051263 microcin E492 biosynthetic process by siderophore ester modification of peptidyl-serine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051263 RESID:AA0374 microcin E492 formation by siderophore ester modification of peptidyl-serine|microcin E492 synthesis by siderophore ester modification of peptidyl-serine|microcin E492 anabolism by siderophore ester modification of peptidyl-serine The modification of serine to N-[5-(6-O-seryl-beta-glucosyl)-2,3-dihydroxybenzoyl]-O-[N-(2,3-dihydroxybenzoyl)-O-[N-(2,3-dihydroxybenzoyl)seryl]seryl]serine as found in microcin E492 produced from the mceA gene in plasmid pJAM229 of the E. coli VCS257 strain and the K. pneumoniae RYC492 strain. GO:0051264 mono-olein transacylation activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051264 monooleoylglycerol transacylase activity|monoolein transacylation|monooleoylglycerol O-acyltransferase activity|acyl-CoA-independent mono-olein transacylation|mono-oleoylglycerol O-acyltransferase activity|mono-oleoylglycerol transacylase activity|MOG transacylation Catalysis of the reaction: mono-olein + mono-olein = diolein + glycerol. Mono-olein, also known as mono-oleoylglycerol, is the monoglyceride formed from oleic acid, 9-octodecenoic acid; diolein is also known as dioleoylglycerol. GO:0075213 obsolete negative regulation of transmembrane receptor-mediated cAMP signal transduction in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075213 negative regulation of symbiont transmembrane receptor-mediated cAMP signal transduction in response to host OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont transmembrane receptor-mediated cAMP signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. UBERON:0008434 cervical vertebral arch biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008434 arch of cervical vertebra A neural arch that is part of a cervical vertebra. GO:2000827 mitochondrial RNA surveillance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000827 RNA surveillance in mitochondria|RNA quality control in mitochondrion|aberrant RNA catabolic process in mitochondria|aberrant RNA catabolic process in mitochondrion|RNA quality control in mitochondria The set of processes involved in identifying and degrading defective or aberrant RNAs that takes place in the mitochondrion. GO:0075247 aeciospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075247 The process in which a dikaryotic spore of typically a rust fungus is produced in an aecium; in heteroecious rusts, the aeciospore is a spore stage that infects the alternate host. GO:2000828 regulation of parathyroid hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000828 regulation of parathormone secretion|regulation of PTH secretion|regulation of parathyrin secretion Any process that modulates the frequency, rate or extent of parathyroid hormone secretion. GO:0075248 regulation of aeciospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075248 Any process that modulates the frequency, rate or extent of aeciospore formation, a process in which a dikaryotic spore of typically a rust fungus is produced in an aecium. GO:0051278 fungal-type cell wall polysaccharide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051278 chitin- and beta-glucan-containing cell wall polysaccharide biosynthetic process|cell wall polysaccharide anabolism|cell wall polysaccharide synthesis|cell wall polysaccharide formation The chemical reactions and pathways resulting in the formation of the polysaccharides which make up the fungal-type cell wall. GO:0075249 positive regulation of aeciospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075249 Any process that activates, maintains or increases the frequency, rate or extent of aeciospore formation, a process in which a dikaryotic spore of typically a rust fungus is produced in an aecium. GO:2000829 negative regulation of parathyroid hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000829 negative regulation of parathyrin secretion|negative regulation of parathormone secretion|negative regulation of PTH secretion Any process that stops, prevents or reduces the frequency, rate or extent of parathyroid hormone secretion. GO:0051279 regulation of release of sequestered calcium ion into cytosol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051279 regulation of cytoplasmic release of sequestered calcium ion (Ca2+)|regulation of release of stored calcium ion (Ca2+) into cytoplasm|regulation of calcium ion (Ca2+) mobilization|regulation of cytoplasmic release of stored calcium ion (Ca2+)|regulation of release of sequestered calcium ion (Ca2+)|regulation of release of stored calcium ion (Ca2+)|regulation of release of stored calcium ion (Ca2+) into cytosol|regulation of calcium mobilization Any process that modulates the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria. GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000820 negative regulation of transcription from RNA polymerase II promoter, global involved in nonstriated muscle cell differentiation|downregulation of global transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|inhibition of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|down regulation of global transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|down regulation of transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|down regulation of global transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|negative regulation of transcription from Pol II promoter involved in smooth muscle cell differentiation|downregulation of transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|downregulation of global transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|negative regulation of transcription from RNA polymerase II promoter, global involved in smooth muscle cell differentiation|inhibition of global transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|negative regulation of global transcription from Pol II promoter involved in smooth muscle cell differentiation|down-regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|down-regulation of transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|negative regulation of transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|down-regulation of global transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|down-regulation of global transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|downregulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|negative regulation of transcription from Pol II promoter involved in nonstriated muscle cell differentiation|down regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|negative regulation of global transcription from Pol II promoter involved in nonstriated muscle cell differentiation|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|inhibition of transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|inhibition of global transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation Any negative regulation of transcription from RNA polymerase II promoter that is involved in smooth muscle cell differentiation. GO:2000821 regulation of grooming behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000821 regulation of grooming behaviour Any process that modulates the frequency, rate or extent of grooming behavior. GO:1905450 negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905450 down-regulation of Fc-gamma receptor signalling pathway involved in phagocytosis|negative regulation of Fc-gamma receptor signalling pathway involved in phagocytosis|down regulation of IgG-mediated phagocytosis|inhibition of Fc-gamma receptor signalling pathway involved in phagocytosis|downregulation of IgG-mediated phagocytosis|down-regulation of Fc-gamma receptor signaling pathway involved in phagocytosis|down-regulation of Fcgamma receptor-mediated phagocytosis|negative regulation of Fc gamma receptor-dependent phagocytosis|negative regulation of Fcgamma receptor-mediated phagocytosis|down-regulation of Fc gamma receptor-dependent phagocytosis|down-regulation of IgG-mediated phagocytosis|negative regulation of IgG-mediated phagocytosis|down regulation of Fc-gamma receptor signalling pathway involved in phagocytosis|downregulation of Fc-gamma receptor signaling pathway involved in phagocytosis|downregulation of Fc gamma receptor-dependent phagocytosis|downregulation of Fcgamma receptor-mediated phagocytosis|down regulation of Fc-gamma receptor signaling pathway involved in phagocytosis|downregulation of Fc-gamma receptor signalling pathway involved in phagocytosis|inhibition of Fc-gamma receptor signaling pathway involved in phagocytosis|inhibition of IgG-mediated phagocytosis|down regulation of Fc gamma receptor-dependent phagocytosis|down regulation of Fcgamma receptor-mediated phagocytosis|inhibition of Fcgamma receptor-mediated phagocytosis|inhibition of Fc gamma receptor-dependent phagocytosis Any process that stops, prevents or reduces the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis. GO:2000822 regulation of behavioral fear response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000822 regulation of behavioural fear response Any process that modulates the frequency, rate or extent of behavioral fear response. GO:1905451 positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905451 positive regulation of Fc-gamma receptor signalling pathway involved in phagocytosis|upregulation of Fc gamma receptor-dependent phagocytosis|upregulation of Fcgamma receptor-mediated phagocytosis|upregulation of IgG-mediated phagocytosis|up-regulation of Fc-gamma receptor signaling pathway involved in phagocytosis|activation of Fc-gamma receptor signaling pathway involved in phagocytosis|up-regulation of Fc gamma receptor-dependent phagocytosis|up-regulation of Fcgamma receptor-mediated phagocytosis|activation of Fcgamma receptor-mediated phagocytosis|activation of Fc gamma receptor-dependent phagocytosis|up-regulation of Fc-gamma receptor signalling pathway involved in phagocytosis|up regulation of IgG-mediated phagocytosis|activation of IgG-mediated phagocytosis|positive regulation of IgG-mediated phagocytosis|up regulation of Fc-gamma receptor signaling pathway involved in phagocytosis|upregulation of Fc-gamma receptor signalling pathway involved in phagocytosis|positive regulation of Fcgamma receptor-mediated phagocytosis|positive regulation of Fc gamma receptor-dependent phagocytosis|up regulation of Fcgamma receptor-mediated phagocytosis|up regulation of Fc gamma receptor-dependent phagocytosis|up-regulation of IgG-mediated phagocytosis|upregulation of Fc-gamma receptor signaling pathway involved in phagocytosis|up regulation of Fc-gamma receptor signalling pathway involved in phagocytosis|activation of Fc-gamma receptor signalling pathway involved in phagocytosis Any process that activates or increases the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis. GO:2000823 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2000823 GO:1905452 obsolete canonical Wnt signaling pathway involved in regulation of stem cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905452 canonical Wnt receptor signaling pathway involved in regulation of stem cell proliferation|Wnt receptor signaling pathway through beta-catenin involved in regulation of stem cell proliferation|canonical Wnt-activated signaling pathway involved in regulation of stem cell proliferation|Wnt receptor signalling pathway through beta-catenin involved in regulation of stem cell proliferation|Wnt receptor signaling pathway via beta-catenin involved in regulation of stem cell proliferation|frizzled-1 receptor signaling pathway involved in regulation of stem cell proliferation OBSOLETE. Any canonical Wnt signaling pathway that is involved in regulation of stem cell proliferation. GO:2000824 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2000824 GO:1905453 regulation of myeloid progenitor cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905453 Any process that modulates the frequency, rate or extent of myeloid progenitor cell differentiation. GO:2000825 positive regulation of androgen receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000825 Any process that activates or increases the frequency, rate or extent of androgen receptor activity. GO:1905454 negative regulation of myeloid progenitor cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905454 down regulation of myeloid progenitor cell differentiation|downregulation of myeloid progenitor cell differentiation|down-regulation of myeloid progenitor cell differentiation|inhibition of myeloid progenitor cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of myeloid progenitor cell differentiation. GO:2000826 regulation of heart morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000826 regulation of cardiac morphogenesis Any process that modulates the frequency, rate or extent of heart morphogenesis. GO:1905444 negative regulation of clathrin coat assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905444 negative regulation of clathrin cage assembly|down-regulation of clathrin cage assembly|down-regulation of clathrin coat assembly|downregulation of clathrin cage assembly|downregulation of clathrin coat assembly|down regulation of clathrin cage assembly|inhibition of clathrin cage assembly|down regulation of clathrin coat assembly|inhibition of clathrin coat assembly Any process that stops, prevents or reduces the frequency, rate or extent of clathrin coat assembly. GO:1905445 positive regulation of clathrin coat assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905445 positive regulation of clathrin cage assembly|up regulation of clathrin cage assembly|up regulation of clathrin coat assembly|upregulation of clathrin cage assembly|upregulation of clathrin coat assembly|up-regulation of clathrin cage assembly|activation of clathrin cage assembly|up-regulation of clathrin coat assembly|activation of clathrin coat assembly Any process that activates or increases the frequency, rate or extent of clathrin coat assembly. GO:1905446 regulation of mitochondrial ATP synthesis coupled electron transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905446 regulation of organelle ATP synthesis coupled electron transport|regulation of mitochondrial electron transport Any process that modulates the frequency, rate or extent of mitochondrial ATP synthesis coupled electron transport. CHEBI:41625 chromopyrrolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_41625 CHEBI:16658 flavonol 3-O-[beta-D-xylosyl-(1->2)-beta-D-glycoside]s biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16658 GO:1905447 negative regulation of mitochondrial ATP synthesis coupled electron transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905447 down-regulation of mitochondrial ATP synthesis coupled electron transport|downregulation of mitochondrial ATP synthesis coupled electron transport|down regulation of mitochondrial ATP synthesis coupled electron transport|inhibition of mitochondrial ATP synthesis coupled electron transport Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial ATP synthesis coupled electron transport. CHEBI:16659 D-glycerate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16659 GO:1905448 positive regulation of mitochondrial ATP synthesis coupled electron transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905448 up-regulation of mitochondrial ATP synthesis coupled electron transport|activation of mitochondrial ATP synthesis coupled electron transport|up regulation of mitochondrial ATP synthesis coupled electron transport|upregulation of mitochondrial ATP synthesis coupled electron transport Any process that activates or increases the frequency, rate or extent of mitochondrial ATP synthesis coupled electron transport. CHEBI:16656 tropinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16656 GO:1905449 regulation of Fc-gamma receptor signaling pathway involved in phagocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905449 regulation of IgG-mediated phagocytosis|regulation of Fc-gamma receptor signalling pathway involved in phagocytosis|regulation of Fc gamma receptor-dependent phagocytosis|regulation of Fcgamma receptor-mediated phagocytosis Any process that modulates the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis. CHEBI:16654 (R)-4-dehydropantoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16654 CHEBI:16655 N-acetyl-3-O-(4-deoxy-alpha-L-threo-hex-4-enopyranosyluronic acid)-D-galactosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16655 GO:0051272 positive regulation of cellular component movement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051272 positive regulation of cellular component motion Any process that activates or increases the frequency, rate or extent of the movement of a cellular component. CHEBI:16652 1,4-diguanidinobutane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16652 GO:0051273 beta-glucan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051273 beta-glucan metabolism The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds. GO:0075240 regulation of zoospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075240 Any process that modulates the frequency, rate or extent of zoospore formation, a process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores. CHEBI:16653 cycloeucalenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16653 GO:0075241 positive regulation of zoospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075241 Any process that activates, maintains or increases the frequency, rate or extent of zoospore formation, a process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores. GO:0051270 regulation of cellular component movement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051270 regulation of cellular component motion|regulation of cell movement Any process that modulates the frequency, rate or extent of the movement of a cellular component. CHEBI:16650 UDP-N-acetyl-D-galactosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16650 GO:0075242 negative regulation of zoospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075242 Any process that stops, prevents, or reduces the frequency, rate or extent of zoospore formation, a process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores. CHEBI:16651 (S)-lactate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16651 GO:0051271 negative regulation of cellular component movement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051271 negative regulation of cellular component motion Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of a cellular component. GO:0075243 oospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075243 The process in which male and female gametangia develop and fuse to form an oospore, a thick-walled resting spore of Oomycetes and certain algae and fungi. GO:0051276 chromosome organization biolink:BiologicalProcess go-plus goslim_generic|goslim_chembl|goslim_pir|goslim_drosophila http://purl.obolibrary.org/obo/GO_0051276 nuclear genome maintenance|maintenance of genome integrity|chromosome organization and biogenesis|chromosome organisation A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome. GO:0075244 regulation of oospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075244 Any process that modulates the frequency, rate or extent of oospore formation, a process in which male and female gametangia develop and fuse to form a thick-walled resting spore of oomycetes. GO:0051277 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051277 GO:0075245 positive regulation of oospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075245 Any process that activates, maintains or increases the frequency, rate or extent of oospore formation, a process in which male and female gametangia develop and fuse to form a thick-walled resting spore of oomycetes. GO:0051274 beta-glucan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051274 beta-glucan anabolism|beta-glucan synthesis|beta-glucan biosynthesis|beta-glucan formation The chemical reactions and pathways resulting in the formation of beta-glucans. GO:0075246 negative regulation of oospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075246 Any process that stops, prevents, or reduces the frequency, rate or extent of oospore formation, a process in which male and female gametangia develop and fuse to form a thick-walled resting spore of oomycetes. GO:0051275 beta-glucan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051275 beta-glucan breakdown|beta-glucan catabolism|beta-glucan degradation The chemical reactions and pathways resulting in the breakdown of beta-glucans. GO:0075236 obsolete positive regulation of zoospore movement on or near host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075236 OBSOLETE. Any process that activates, maintains or increases the frequency, rate or extent of zoospore movement on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:2000838 negative regulation of androstenedione secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000838 negative regulation of androst-4-ene-3,17-dione secretion Any process that stops, prevents or reduces the frequency, rate or extent of androstenedione secretion. GO:2000839 positive regulation of androstenedione secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000839 positive regulation of androst-4-ene-3,17-dione secretion Any process that activates or increases the frequency, rate or extent of androstenedione secretion. GO:0075237 obsolete obsolete negative regulation of zoospore movement on or near host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075237 OBSOLETE. OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of zoospore movement on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075238 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075238 GO:0051289 protein homotetramerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051289 protein homotetramer formation|protein homotetramer biosynthetic process|protein homotetramer biosynthesis|protein homotetramer assembly The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits. GO:0075239 zoospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075239 The process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores. GO:2000830 positive regulation of parathyroid hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000830 positive regulation of parathyrin secretion|positive regulation of PTH secretion|positive regulation of parathormone secretion Any process that activates or increases the frequency, rate or extent of parathyroid hormone secretion. GO:2000831 regulation of steroid hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000831 Any process that modulates the frequency, rate or extent of steroid hormone secretion. GO:1905460 negative regulation of vascular associated smooth muscle cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905460 down-regulation of vascular associated smooth muscle cell apoptotic process|inhibition of vascular smooth muscle cell apoptotic process|inhibition of vascular smooth muscle cell apoptosis|down-regulation of VSMC apoptosis|downregulation of vascular associated smooth muscle cell apoptosis|negative regulation of VSMC apoptosis|down regulation of vascular associated smooth muscle cell apoptosis|down-regulation of VSMC apoptotic process|downregulation of vascular associated smooth muscle cell apoptotic process|negative regulation of VSMC apoptotic process|down regulation of vascular smooth muscle cell apoptosis|downregulation of VSMC apoptosis|down regulation of vascular associated smooth muscle cell apoptotic process|downregulation of vascular smooth muscle cell apoptosis|inhibition of vascular associated smooth muscle cell apoptosis|inhibition of vascular associated smooth muscle cell apoptotic process|down regulation of vascular smooth muscle cell apoptotic process|down regulation of VSMC apoptosis|downregulation of VSMC apoptotic process|downregulation of vascular smooth muscle cell apoptotic process|down regulation of VSMC apoptotic process|negative regulation of vascular smooth muscle cell apoptosis|down-regulation of vascular smooth muscle cell apoptosis|inhibition of VSMC apoptotic process|inhibition of VSMC apoptosis|down-regulation of vascular associated smooth muscle cell apoptosis|negative regulation of vascular associated smooth muscle cell apoptosis|negative regulation of vascular smooth muscle cell apoptotic process|down-regulation of vascular smooth muscle cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process. GO:2000832 negative regulation of steroid hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000832 Any process that stops, prevents or reduces the frequency, rate or extent of steroid hormone secretion. GO:1905461 positive regulation of vascular associated smooth muscle cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905461 positive regulation of vascular associated smooth muscle cell apoptosis|up regulation of vascular associated smooth muscle cell apoptosis|activation of VSMC apoptotic process|up-regulation of VSMC apoptotic process|activation of VSMC apoptosis|up-regulation of vascular smooth muscle cell apoptotic process|up regulation of vascular associated smooth muscle cell apoptotic process|upregulation of vascular smooth muscle cell apoptosis|positive regulation of VSMC apoptosis|up regulation of VSMC apoptosis|upregulation of vascular associated smooth muscle cell apoptosis|upregulation of vascular smooth muscle cell apoptotic process|positive regulation of VSMC apoptotic process|up regulation of VSMC apoptotic process|upregulation of vascular associated smooth muscle cell apoptotic process|up regulation of vascular smooth muscle cell apoptosis|positive regulation of vascular smooth muscle cell apoptosis|upregulation of VSMC apoptosis|up-regulation of vascular associated smooth muscle cell apoptosis|up regulation of vascular smooth muscle cell apoptotic process|activation of vascular smooth muscle cell apoptotic process|activation of vascular smooth muscle cell apoptosis|positive regulation of vascular smooth muscle cell apoptotic process|up-regulation of vascular associated smooth muscle cell apoptotic process|upregulation of VSMC apoptotic process|activation of vascular associated smooth muscle cell apoptosis|activation of vascular associated smooth muscle cell apoptotic process|up-regulation of VSMC apoptosis|up-regulation of vascular smooth muscle cell apoptosis Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process. GO:2000833 positive regulation of steroid hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000833 Any process that activates or increases the frequency, rate or extent of steroid hormone secretion. GO:1905462 regulation of DNA duplex unwinding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905462 regulation of duplex DNA melting|regulation of DNA unwinding Any process that modulates the frequency, rate or extent of DNA duplex unwinding. GO:2000834 regulation of androgen secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000834 Any process that modulates the frequency, rate or extent of androgen secretion. GO:1905463 negative regulation of DNA duplex unwinding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905463 downregulation of duplex DNA melting|down regulation of duplex DNA melting|inhibition of duplex DNA melting|down-regulation of DNA duplex unwinding|down regulation of DNA unwinding|downregulation of DNA unwinding|downregulation of DNA duplex unwinding|down regulation of DNA duplex unwinding|negative regulation of DNA unwinding|inhibition of DNA duplex unwinding|down-regulation of DNA unwinding|down-regulation of duplex DNA melting|negative regulation of duplex DNA melting|inhibition of DNA unwinding Any process that stops, prevents or reduces the frequency, rate or extent of DNA duplex unwinding. GO:2000835 negative regulation of androgen secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000835 Any process that stops, prevents or reduces the frequency, rate or extent of androgen secretion. GO:1905464 positive regulation of DNA duplex unwinding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905464 up-regulation of DNA duplex unwinding|activation of DNA duplex unwinding|upregulation of DNA unwinding|upregulation of duplex DNA melting|up regulation of DNA duplex unwinding|up regulation of DNA unwinding|activation of DNA unwinding|up-regulation of duplex DNA melting|positive regulation of DNA unwinding|activation of duplex DNA melting|upregulation of DNA duplex unwinding|up-regulation of DNA unwinding|positive regulation of duplex DNA melting|up regulation of duplex DNA melting Any process that activates or increases the frequency, rate or extent of DNA duplex unwinding. GO:2000836 positive regulation of androgen secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000836 Any process that activates or increases the frequency, rate or extent of androgen secretion. GO:1905465 regulation of G-quadruplex DNA unwinding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905465 Any process that modulates the frequency, rate or extent of G-quadruplex DNA unwinding. GO:2000837 regulation of androstenedione secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000837 regulation of androst-4-ene-3,17-dione secretion Any process that modulates the frequency, rate or extent of androstenedione secretion. GO:1905455 positive regulation of myeloid progenitor cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905455 upregulation of myeloid progenitor cell differentiation|up regulation of myeloid progenitor cell differentiation|activation of myeloid progenitor cell differentiation|up-regulation of myeloid progenitor cell differentiation Any process that activates or increases the frequency, rate or extent of myeloid progenitor cell differentiation. GO:1905456 regulation of lymphoid progenitor cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905456 Any process that modulates the frequency, rate or extent of lymphoid progenitor cell differentiation. CHEBI:16647 L-fuculose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16647 GO:1905457 negative regulation of lymphoid progenitor cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905457 downregulation of lymphoid progenitor cell differentiation|down regulation of lymphoid progenitor cell differentiation|inhibition of lymphoid progenitor cell differentiation|down-regulation of lymphoid progenitor cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of lymphoid progenitor cell differentiation. GO:1905458 positive regulation of lymphoid progenitor cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905458 up regulation of lymphoid progenitor cell differentiation|upregulation of lymphoid progenitor cell differentiation|up-regulation of lymphoid progenitor cell differentiation|activation of lymphoid progenitor cell differentiation Any process that activates or increases the frequency, rate or extent of lymphoid progenitor cell differentiation. CHEBI:16648 dialkyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16648 GO:1905459 regulation of vascular associated smooth muscle cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905459 regulation of vascular smooth muscle cell apoptosis|regulation of VSMC apoptosis|regulation of vascular smooth muscle cell apoptotic process|regulation of VSMC apoptotic process|regulation of vascular associated smooth muscle cell apoptosis Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process. CHEBI:16645 preuroporphyrinogen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16645 GO:0051280 negative regulation of release of sequestered calcium ion into cytosol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051280 downregulation of release of sequestered calcium ion into cytosol|negative regulation of cytoplasmic release of sequestered calcium ion (Ca2+)|negative regulation of calcium mobilization|negative regulation of cytosolic release of stored calcium ion (Ca2+)|negative regulation of cytosolic release of sequestered calcium ion (Ca2+)|negative regulation of release of sequestered calcium ion into cytoplasm|negative regulation of calcium ion (Ca2+) mobilization|negative regulation of release of stored calcium ion (Ca2+) into cytoplasm|down-regulation of release of sequestered calcium ion into cytosol|negative regulation of release of sequestered calcium ion (Ca2+)|negative regulation of release of stored calcium ion (Ca2+) into cytosol|inhibition of release of sequestered calcium ion into cytosol|negative regulation of release of stored calcium ion (Ca2+)|down regulation of release of sequestered calcium ion into cytosol|negative regulation of cytoplasmic release of stored calcium ion (Ca2+) Any process that stops, prevents, or reduces the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria. CHEBI:16646 carbohydrate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16646 CHEBI:16643 L-methionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16643 CHEBI:16641 ethyl (R)-3-hydroxyhexanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16641 GO:0051283 negative regulation of sequestering of calcium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051283 down-regulation of sequestering of calcium ion|negative regulation of calcium ion (Ca2+) sequestration|negative regulation of sequestering of calcium ion (Ca2+)|inhibition of sequestering of calcium ion|negative regulation of retention of calcium ion (Ca2+)|negative regulation of storage of calcium ion (Ca2+)|down regulation of sequestering of calcium ion|negative regulation of sequestration of calcium ion (Ca2+)|negative regulation of calcium ion (Ca2+) retention|negative regulation of calcium ion (Ca2+) sequestering|downregulation of sequestering of calcium ion|negative regulation of calcium ion (Ca2+) storage Any process that stops, prevents, or reduces the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system. GO:0051284 positive regulation of sequestering of calcium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051284 positive regulation of calcium ion (Ca2+) retention|up regulation of sequestering of calcium ion|activation of sequestering of calcium ion|positive regulation of calcium ion (Ca2+) storage|stimulation of sequestering of calcium ion|positive regulation of calcium ion (Ca2+) sequestration|positive regulation of retention of calcium ion (Ca2+)|up-regulation of sequestering of calcium ion|positive regulation of storage of calcium ion (Ca2+)|positive regulation of sequestering of calcium ion (Ca2+)|positive regulation of sequestration of calcium ion (Ca2+)|upregulation of sequestering of calcium ion|positive regulation of calcium ion (Ca2+) sequestering Any process that activates or increases the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system. GO:0051281 positive regulation of release of sequestered calcium ion into cytosol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051281 positive regulation of cytoplasmic release of sequestered calcium ion (Ca2+)|positive regulation of cytoplasmic release of stored calcium ion (Ca2+)|positive regulation of cytosolic release of sequestered calcium ion (Ca2+)|positive regulation of release of sequestered calcium ion into cytoplasm|up regulation of release of sequestered calcium ion into cytosol|positive regulation of release of stored calcium ion (Ca2+) into cytoplasm|activation of release of sequestered calcium ion into cytosol|positive regulation of calcium ion (Ca2+) mobilization|positive regulation of release of sequestered calcium ion (Ca2+)|positive regulation of cytosolic release of stored calcium ion (Ca2+)|positive regulation of calcium mobilization|stimulation of release of sequestered calcium ion into cytosol|positive regulation of release of stored calcium ion (Ca2+) into cytosol|up-regulation of release of sequestered calcium ion into cytosol|positive regulation of release of stored calcium ion (Ca2+)|upregulation of release of sequestered calcium ion into cytosol Any process that activates or increases the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria. GO:0075230 obsolete spore movement on or near host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075230 OBSOLETE. Any process involved in the directed movement of a motile spore on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051282 regulation of sequestering of calcium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051282 regulation of retention of calcium ion (Ca2+)|regulation of storage of calcium ion (Ca2+)|regulation of calcium ion (Ca2+) retention|regulation of calcium ion (Ca2+) storage|regulation of sequestration of calcium ion (Ca2+)|regulation of calcium ion (Ca2+) sequestration|regulation of calcium ion (Ca2+) sequestering|regulation of sequestering of calcium ion (Ca2+) Any process that modulates the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system. GO:0075231 obsolete modulation of spore movement on or near host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075231 OBSOLETE. Any process that modulates the frequency, rate or extent of spore movement on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051287 NAD binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0051287 NAD+ or NADH binding|NAD or NADH binding|nicotinamide adenine dinucleotide binding Interacting selectively and non-covalently with nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH. GO:0075232 obsolete positive regulation of spore movement on or near host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075232 OBSOLETE. Any process that activates, maintains or increases the frequency, rate or extent of spore movement on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075233 obsolete negative regulation of spore movement on or near host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075233 OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of spore movement on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051288 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051288 GO:0051285 cell cortex of cell tip biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0051285 cell cortex of cell end The region directly beneath the plasma membrane at the cell tip. The cell tip is the region at either end of the longest axis of a cylindrical or elongated cell. GO:0075234 obsolete zoospore movement on or near host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075234 zoospore motility on or near host OBSOLETE. Any process involved in the directed movement of a zoospore on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075235 obsolete modulation of zoospore movement on or near host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075235 regulation of zoospore motility on or near host OBSOLETE. Any process that modulates the frequency, rate or extent of zoospore movement on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051286 cell tip biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0051286 cell end The region at the end of the longest axis of a cylindrical or elongated cell. GO:0075269 positive regulation of aecium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075269 Any process that activates, maintains or increases the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed. GO:2000849 regulation of glucocorticoid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000849 Any process that modulates the frequency, rate or extent of glucocorticoid secretion. GO:2000841 negative regulation of dehydroepiandrosterone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000841 negative regulation of dehydroisoandrosterone secretion|negative regulation of 3beta-hydroxyandrost-5-en-17-one secretion|negative regulation of DHEA secretion Any process that stops, prevents or reduces the frequency, rate or extent of dehydroepiandrosterone secretion. GO:1905470 positive regulation of clathrin-coated pit assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905470 upregulation of clathrin-coated pit assembly|upregulation of coated pit formation|up regulation of coated pit assembly|up regulation of clathrin-coated pit formation|positive regulation of coated pit assembly|activation of coated pit assembly|activation of clathrin-coated pit formation|positive regulation of clathrin-coated pit formation|up-regulation of clathrin-coated pit assembly|up-regulation of coated pit formation|activation of clathrin-coated pit assembly|activation of coated pit formation|up-regulation of coated pit assembly|up-regulation of clathrin-coated pit formation|positive regulation of coated pit formation|up regulation of clathrin-coated pit assembly|up regulation of coated pit formation|upregulation of coated pit assembly|upregulation of clathrin-coated pit formation Any process that activates or increases the frequency, rate or extent of clathrin-coated pit assembly. GO:2000842 positive regulation of dehydroepiandrosterone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000842 positive regulation of DHEA secretion|positive regulation of dehydroisoandrosterone secretion|positive regulation of 3beta-hydroxyandrost-5-en-17-one secretion Any process that activates or increases the frequency, rate or extent of dehydroepiandrosterone secretion. GO:2000843 regulation of testosterone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000843 Any process that modulates the frequency, rate or extent of testosterone secretion. GO:1905471 regulation of histone H3-K79 dimethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905471 regulation of histone H3 K79 dimethylation|regulation of histone lysine H3 K79 dimethylation Any process that modulates the frequency, rate or extent of histone H3-K79 dimethylation. GO:1905472 negative regulation of histone H3-K79 dimethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905472 downregulation of histone H3 K79 dimethylation|down-regulation of histone H3-K79 dimethylation|down regulation of histone H3 K79 dimethylation|negative regulation of histone lysine H3 K79 dimethylation|down-regulation of histone lysine H3 K79 dimethylation|inhibition of histone H3 K79 dimethylation|inhibition of histone lysine H3 K79 dimethylation|downregulation of histone H3-K79 dimethylation|down regulation of histone H3-K79 dimethylation|inhibition of histone H3-K79 dimethylation|down-regulation of histone H3 K79 dimethylation|negative regulation of histone H3 K79 dimethylation|down regulation of histone lysine H3 K79 dimethylation|downregulation of histone lysine H3 K79 dimethylation Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K79 dimethylation. GO:2000844 negative regulation of testosterone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000844 Any process that stops, prevents or reduces the frequency, rate or extent of testosterone secretion. GO:1905473 positive regulation of histone H3-K79 dimethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905473 up-regulation of histone H3-K79 dimethylation|activation of histone H3-K79 dimethylation|up regulation of histone H3 K79 dimethylation|up regulation of histone lysine H3 K79 dimethylation|activation of histone lysine H3 K79 dimethylation|positive regulation of histone lysine H3 K79 dimethylation|upregulation of histone H3 K79 dimethylation|up regulation of histone H3-K79 dimethylation|up-regulation of histone lysine H3 K79 dimethylation|up-regulation of histone H3 K79 dimethylation|activation of histone H3 K79 dimethylation|upregulation of histone H3-K79 dimethylation|upregulation of histone lysine H3 K79 dimethylation|positive regulation of histone H3 K79 dimethylation Any process that activates or increases the frequency, rate or extent of histone H3-K79 dimethylation. GO:2000845 positive regulation of testosterone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000845 Any process that activates or increases the frequency, rate or extent of testosterone secretion. GO:1905474 canonical Wnt signaling pathway involved in stem cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905474 Wnt receptor signalling pathway through beta-catenin involved in stem cell proliferation|canonical Wnt-activated signaling pathway involved in stem cell proliferation|Wnt receptor signaling pathway via beta-catenin involved in stem cell proliferation|frizzled-1 receptor signaling pathway involved in stem cell proliferation|canonical Wnt receptor signaling pathway involved in stem cell proliferation|Wnt receptor signaling pathway through beta-catenin involved in stem cell proliferation Any canonical Wnt signaling pathway that is involved in stem cell proliferation. GO:2000846 regulation of corticosteroid hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000846 regulation of corticosteroid secretion Any process that modulates the frequency, rate or extent of corticosteroid hormone secretion. GO:1905475 regulation of protein localization to membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905475 regulation of protein localisation in membrane|regulation of protein localization in membrane Any process that modulates the frequency, rate or extent of protein localization to membrane. GO:2000847 negative regulation of corticosteroid hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000847 negative regulation of corticosteroid secretion Any process that stops, prevents or reduces the frequency, rate or extent of corticosteroid hormone secretion. GO:1905476 negative regulation of protein localization to membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905476 inhibition of protein localization to membrane|down regulation of protein localisation in membrane|inhibition of protein localisation in membrane|downregulation of protein localization in membrane|down regulation of protein localization in membrane|inhibition of protein localization in membrane|down-regulation of protein localization to membrane|negative regulation of protein localisation in membrane|down-regulation of protein localisation in membrane|downregulation of protein localization to membrane|down-regulation of protein localization in membrane|negative regulation of protein localization in membrane|downregulation of protein localisation in membrane|down regulation of protein localization to membrane Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to membrane. GO:2000848 positive regulation of corticosteroid hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000848 positive regulation of corticosteroid secretion Any process that activates or increases the frequency, rate or extent of corticosteroid hormone secretion. GO:1905466 negative regulation of G-quadruplex DNA unwinding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905466 downregulation of G-quadruplex DNA unwinding|down regulation of G-quadruplex DNA unwinding|inhibition of G-quadruplex DNA unwinding|down-regulation of G-quadruplex DNA unwinding Any process that stops, prevents or reduces the frequency, rate or extent of G-quadruplex DNA unwinding. GO:1905467 positive regulation of G-quadruplex DNA unwinding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905467 up regulation of G-quadruplex DNA unwinding|upregulation of G-quadruplex DNA unwinding|up-regulation of G-quadruplex DNA unwinding|activation of G-quadruplex DNA unwinding Any process that activates or increases the frequency, rate or extent of G-quadruplex DNA unwinding. GO:1905468 regulation of clathrin-coated pit assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905468 regulation of coated pit formation|regulation of coated pit assembly|regulation of clathrin-coated pit formation Any process that modulates the frequency, rate or extent of clathrin-coated pit assembly. GO:1905469 negative regulation of clathrin-coated pit assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905469 down-regulation of coated pit assembly|negative regulation of coated pit assembly|negative regulation of clathrin-coated pit formation|down-regulation of clathrin-coated pit formation|down-regulation of clathrin-coated pit assembly|inhibition of coated pit assembly|negative regulation of coated pit formation|down-regulation of coated pit formation|inhibition of clathrin-coated pit formation|downregulation of clathrin-coated pit assembly|downregulation of coated pit formation|down regulation of coated pit assembly|down regulation of clathrin-coated pit assembly|down regulation of clathrin-coated pit formation|down regulation of coated pit formation|inhibition of clathrin-coated pit assembly|inhibition of coated pit formation|downregulation of coated pit assembly|downregulation of clathrin-coated pit formation Any process that stops, prevents or reduces the frequency, rate or extent of clathrin-coated pit assembly. GO:0051290 protein heterotetramerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051290 protein heterotetramer assembly|protein heterotetramer formation|protein heterotetramer biosynthetic process|protein heterotetramer biosynthesis The formation of a protein heterotetramer, a macromolecular structure consisting of four noncovalently associated subunits, of which not all are identical. GO:0051291 protein heterooligomerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051291 protein heterooligomer assembly|protein heterooligomer formation|protein heterooligomer biosynthetic process|protein heterooligomer biosynthesis The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers that are not all identical. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer. GO:2000840 regulation of dehydroepiandrosterone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000840 regulation of DHEA secretion|regulation of dehydroisoandrosterone secretion|regulation of 3beta-hydroxyandrost-5-en-17-one secretion Any process that modulates the frequency, rate or extent of dehydroepiandrosterone secretion. GO:0075260 regulation of spore-bearing organ development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075260 Any process that modulates the frequency, rate or extent of spore-bearing organ development, a process in which hyphae grow into special aggregates called fruiting bodies that produce new spores. GO:0051294 establishment of spindle orientation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051294 orienting of spindle|spindle orientation Any process that set the alignment of spindle relative to other cellular structures. GO:0075261 positive regulation of spore-bearing organ development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075261 Any process that activates, maintains or increases the frequency, rate or extent of spore-bearing organ development, a process in which hyphae grow into special aggregates called fruiting bodies that produce new spores. GO:0051295 establishment of meiotic spindle localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051295 establishment of meiotic spindle localisation|spindle positioning involved in meiotic cell cycle|spindle positioning during meiosis|meiotic spindle positioning The cell cycle process in which the directed movement of the meiotic spindle to a specific location in the cell occurs. CHEBI:16675 quinolinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16675 GO:0075262 negative regulation of spore-bearing organ development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075262 Any process that stops, prevents, or reduces the frequency, rate or extent of spore-bearing organ development, a process in which hyphae grow into special aggregates called fruiting bodies that produce new spores. GO:0051292 nuclear pore complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051292 nuclear pore assembly|nuclear pore biogenesis|nuclear pore complex biosynthesis|nuclear pore complex formation|NPC assembly|nuclear pore complex biogenesis|nuclear pore biosynthesis|nuclear pore formation The aggregation, arrangement and bonding together of a set of components to form a nuclear pore complex. GO:0075263 oogonium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075263 The process that leads to the development of an oogonium, a female gametangium of Oomycetes, containing one or more gametes. GO:0051293 establishment of spindle localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051293 spindle positioning|establishment of spindle localisation The directed movement of the spindle to a specific location in the cell. GO:0075264 regulation of oogonium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075264 Any process that modulates the frequency, rate or extent of oogonium development, a process that leads to the formation of a female gametangium of oomycetes, containing one or more gametes. CHEBI:16673 protochlorophyllide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16673 GO:0075265 positive regulation of oogonium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075265 Any process that activates, maintains or increases the frequency, rate or extent of oogonium development, a process that leads to the formation of a female gametangium of oomycetes, containing one or more gametes. CHEBI:41609 carbonate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_41609 GO:0051298 centrosome duplication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051298 centrosome replication The replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized. CHEBI:16670 peptide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16670 CHEBI:16671 4-guanidinobutanal biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16671 GO:0051299 centrosome separation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051299 The process in which duplicated centrosome components move away from each other. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle. GO:0075266 negative regulation of oogonium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075266 Any process that stops, prevents, or reduces the frequency, rate or extent of oogonium development, a process that leads to the formation of a female gametangium of oomycetes, containing one or more gametes. GO:0051296 establishment of meiotic spindle orientation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051296 meiotic spindle orientation|establishment of spindle orientation involved in meiotic cell cycle|establishment of spindle orientation during meiosis|orienting of meiotic spindle Any process that set the alignment of meiotic spindle relative to other cellular structures. GO:0075267 aecium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075267 The process in which a cup-like structure containing chains of aeciospores is formed. This is characteristic of the rust fungus and typically, the first dikaryotic spores (aeciospores) are produced in the aecium. GO:0075268 regulation of aecium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075268 Any process that modulates the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed. GO:0051297 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051297 GO:0075258 negative regulation of teliospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075258 Any process that stops, prevents, or reduces the frequency, rate or extent of teliospore formation, which is the formation of a thick-walled resting or overwintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs. GO:0075259 spore-bearing structure development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075259 fruiting structure development|sporangium development|sporophore development|spore-bearing organ development The process whose specific outcome is the progression of a spore-bearing structure over time, from its formation to the mature structure. A spore-bearing structure is an anatomical structure that produces new spores. GO:1905480 positive regulation of glutamate-ammonia ligase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905480 upregulation of glutamine synthetase activity|upregulation of L-glutamine synthetase activity|upregulation of glutamylhydroxamic synthetase activity|upregulation of glutamate-ammonia ligase activity|up-regulation of L-glutamate:ammonia ligase (ADP-forming)|activation of L-glutamate:ammonia ligase (ADP-forming)|up regulation of glutamine synthetase activity|up regulation of L-glutamine synthetase activity|activation of glutamine synthetase activity|positive regulation of glutamine synthetase activity|up-regulation of glutamylhydroxamic synthetase activity|activation of L-glutamine synthetase activity|activation of glutamylhydroxamic synthetase activity|positive regulation of L-glutamine synthetase activity|up regulation of glutamate-ammonia ligase activity|activation of glutamate-ammonia ligase activity|positive regulation of L-glutamate:ammonia ligase (ADP-forming)|up regulation of L-glutamate:ammonia ligase (ADP-forming)|positive regulation of glutamylhydroxamic synthetase activity|up-regulation of glutamine synthetase activity|up-regulation of L-glutamine synthetase activity|up regulation of glutamylhydroxamic synthetase activity|up-regulation of glutamate-ammonia ligase activity|upregulation of L-glutamate:ammonia ligase (ADP-forming) Any process that activates or increases the frequency, rate or extent of glutamate-ammonia ligase activity. GO:2000852 regulation of corticosterone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000852 Any process that modulates the frequency, rate or extent of corticosterone secretion. GO:1905481 obsolete cytoplasmic sequestering of protein involved in mitotic DNA replication checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905481 OBSOLETE. Any cytoplasmic sequestering of protein that is involved in mitotic DNA replication checkpoint. GO:2000853 negative regulation of corticosterone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000853 Any process that stops, prevents or reduces the frequency, rate or extent of corticosterone secretion. GO:1905482 obsolete cytoplasmic sequestering of protein involved in G2 DNA damage checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905482 OBSOLETE. Any cytoplasmic sequestering of protein that is involved in G2 DNA damage checkpoint. GO:2000854 positive regulation of corticosterone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000854 Any process that activates or increases the frequency, rate or extent of corticosterone secretion. GO:1905483 regulation of motor neuron migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905483 Any process that modulates the frequency, rate or extent of motor neuron migration. GO:2000855 regulation of mineralocorticoid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000855 Any process that modulates the frequency, rate or extent of mineralocorticoid secretion. GO:1905484 negative regulation of motor neuron migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905484 down-regulation of motor neuron migration|downregulation of motor neuron migration|down regulation of motor neuron migration|inhibition of motor neuron migration Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron migration. GO:2000856 negative regulation of mineralocorticoid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000856 Any process that stops, prevents or reduces the frequency, rate or extent of mineralocorticoid secretion. GO:1905485 positive regulation of motor neuron migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905485 up regulation of motor neuron migration|upregulation of motor neuron migration|activation of motor neuron migration|up-regulation of motor neuron migration Any process that activates or increases the frequency, rate or extent of motor neuron migration. GO:2000857 positive regulation of mineralocorticoid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000857 Any process that activates or increases the frequency, rate or extent of mineralocorticoid secretion. GO:1905486 regulation of anterior/posterior axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905486 regulation of anterior-posterior axon guidance|regulation of anterior/posterior axon pathfinding Any process that modulates the frequency, rate or extent of anterior/posterior axon guidance. GO:2000858 regulation of aldosterone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000858 Any process that modulates the frequency, rate or extent of aldosterone secretion. GO:1905487 negative regulation of anterior/posterior axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905487 negative regulation of anterior-posterior axon guidance|down-regulation of anterior-posterior axon guidance|down-regulation of anterior/posterior axon guidance|down regulation of anterior/posterior axon pathfinding|downregulation of anterior-posterior axon guidance|downregulation of anterior/posterior axon guidance|downregulation of anterior/posterior axon pathfinding|down regulation of anterior-posterior axon guidance|inhibition of anterior-posterior axon guidance|down regulation of anterior/posterior axon guidance|inhibition of anterior/posterior axon guidance|negative regulation of anterior/posterior axon pathfinding|down-regulation of anterior/posterior axon pathfinding|inhibition of anterior/posterior axon pathfinding Any process that stops, prevents or reduces the frequency, rate or extent of anterior/posterior axon guidance. GO:2000859 negative regulation of aldosterone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000859 Any process that stops, prevents or reduces the frequency, rate or extent of aldosterone secretion. GO:1905477 positive regulation of protein localization to membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905477 positive regulation of protein localization in membrane|up regulation of protein localization in membrane|upregulation of protein localization to membrane|upregulation of protein localisation in membrane|up-regulation of protein localization to membrane|activation of protein localization to membrane|upregulation of protein localization in membrane|activation of protein localisation in membrane|up-regulation of protein localisation in membrane|up-regulation of protein localization in membrane|activation of protein localization in membrane|up regulation of protein localization to membrane|positive regulation of protein localisation in membrane|up regulation of protein localisation in membrane Any process that activates or increases the frequency, rate or extent of protein localization to membrane. GO:1905478 regulation of glutamate-ammonia ligase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905478 regulation of L-glutamate:ammonia ligase (ADP-forming)|regulation of glutamylhydroxamic synthetase activity|regulation of glutamine synthetase activity|regulation of L-glutamine synthetase activity Any process that modulates the frequency, rate or extent of glutamate-ammonia ligase activity. GO:1905479 negative regulation of glutamate-ammonia ligase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905479 downregulation of glutamate-ammonia ligase activity|negative regulation of L-glutamate:ammonia ligase (ADP-forming)|down-regulation of L-glutamate:ammonia ligase (ADP-forming)|down-regulation of glutamine synthetase activity|negative regulation of glutamine synthetase activity|down-regulation of L-glutamine synthetase activity|negative regulation of L-glutamine synthetase activity|negative regulation of glutamylhydroxamic synthetase activity|down-regulation of glutamylhydroxamic synthetase activity|down-regulation of glutamate-ammonia ligase activity|downregulation of L-glutamate:ammonia ligase (ADP-forming)|inhibition of glutamine synthetase activity|inhibition of L-glutamine synthetase activity|down regulation of L-glutamate:ammonia ligase (ADP-forming)|inhibition of glutamate-ammonia ligase activity|downregulation of glutamylhydroxamic synthetase activity|inhibition of L-glutamate:ammonia ligase (ADP-forming)|down regulation of glutamylhydroxamic synthetase activity|inhibition of glutamylhydroxamic synthetase activity|down regulation of glutamine synthetase activity|down regulation of L-glutamine synthetase activity|downregulation of glutamine synthetase activity|down regulation of glutamate-ammonia ligase activity|downregulation of L-glutamine synthetase activity Any process that stops, prevents or reduces the frequency, rate or extent of glutamate-ammonia ligase activity. CHEBI:16669 5-dehydro-2-deoxy-D-gluconate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16669 CHEBI:16667 (4-hydroxyphenyl)acetonitrile biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16667 CHEBI:16668 hypotaurine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16668 GO:2000850 negative regulation of glucocorticoid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000850 Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid secretion. GO:2000851 positive regulation of glucocorticoid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000851 Any process that activates or increases the frequency, rate or extent of glucocorticoid secretion. CHEBI:16666 prephenic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16666 GO:0075250 negative regulation of aeciospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075250 Any process that stops, prevents, or reduces the frequency, rate or extent of aeciospore formation, a process in which a dikaryotic spore of typically a rust fungus is produced in an aecium. CHEBI:16663 poly-cis-polyprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16663 CHEBI:16664 albendazole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16664 GO:0075251 uredospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075251 urediniospore formation|ureidospore formation The process which specific outcome is the formation of an asexual, dikaryotic, often rusty-colored spore, produced in a structure called a uredinium; mostly found in the rust fungus. GO:0075252 regulation of uredospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075252 regulation of ureidospore formation Any process that modulates the frequency, rate or extent of uredospore formation, a process in which an asexual, dikaryotic, often rusty-colored spore, is formed in a structure called a uredinium. GO:0075253 positive regulation of uredospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075253 positive regulation of ureidospore formation Any process that activates, maintains or increases the frequency, rate or extent of uredospore formation, a process in which an asexual, dikaryotic, often rusty-colored spore, is formed in a structure called a uredinium. GO:0075254 negative regulation of uredospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075254 negative regulation of ureidospore formation Any process that stops, prevents, or reduces the frequency, rate or extent of uredospore formation, a process in which an asexual, dikaryotic, often rusty-colored spore, is formed in a structure called a uredinium. GO:0075255 teliospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075255 The set of processes leading to the formation of a thick-walled resting or over-wintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs. CHEBI:16660 (S)-4-hydroxymandelonitrile biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16660 GO:0075256 regulation of teliospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075256 Any process that modulates the frequency, rate or extent of teliospore formation, which is the formation of a thick-walled resting or over-wintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs. GO:0075257 positive regulation of teliospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075257 Any process that activates, maintains or increases the frequency, rate or extent of teliospore formation, which is the formation of a thick-walled resting or overwintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs. GO:0002225 positive regulation of antimicrobial peptide production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002225 up-regulation of antimicrobial peptide production|activation of antimicrobial peptide production|up regulation of antimicrobial peptide production|antimicrobial peptide induction|upregulation of antimicrobial peptide production|stimulation of antimicrobial peptide production Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide production. GO:0002226 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0002226 GO:0002227 innate immune response in mucosa biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002227 Any process of the innate immune response that takes place in the mucosal tissues. GO:0002228 natural killer cell mediated immunity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002228 NK cell mediated immunity The promotion of an immune response by natural killer cells through direct recognition of target cells or through the release of cytokines. GO:0002221 pattern recognition receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002221 pathogen receptor signalling pathway|PAMP receptor signaling pathway|pathogen receptor signaling pathway|PRR signaling pathway Any series of molecular signals generated as a consequence of a pattern recognition receptor (PRR) binding to one of its physiological ligands. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species, or damage-associated molecular pattern (DAMPs), endogenous molecules released from damaged cells. GO:0002222 stimulatory killer cell immunoglobulin-like receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002222 stimulatory KIR signaling pathway|stimulatory killer cell immunoglobulin-like receptor signalling pathway Any series of molecular signals generated as a consequence of binding to a killer cell immunoglobulin-like receptor capable of cellular activation. CHEBI:145326 2,3-dehydroamino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145326 GO:0002223 stimulatory C-type lectin receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002223 stimulatory C-type lectin receptor signalling pathway|stimulatory Ly49 family receptor signaling pathway Any series of molecular signals generated as a consequence of binding to a C-type lectin receptor capable of cellular activation. GO:0002224 toll-like receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002224 toll-like receptor signalling pathway|TLR signaling pathway Any series of molecular signals generated as a consequence of binding to a toll-like receptor. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response. GO:0002220 innate immune response activating cell surface receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002220 innate immune response activating cell surface receptor signalling pathway|activation of innate immune response by cell surface receptor signaling pathway Any series of molecular signals leading to activation of the innate immune response generated as a consequence of binding to a cell surface receptor. GO:0016866 intramolecular transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016866 EC:5.4.-.- mutase activity|intramolecular transferase activity, transferring other groups Catalysis of the transfer of a functional group from one position to another within a single molecule. GO:0016867 intramolecular transferase activity, transferring acyl groups biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016867 EC:5.4.1.- Catalysis of the transfer of an acyl group from one position to another within a single molecule. GO:0016868 intramolecular transferase activity, phosphotransferases biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016868 EC:5.4.2.- phosphotransferase activity, with regeneration of donors, apparently catalyzing intramolecular transfers|phosphomutase activity Catalysis of the transfer of a phosphate group from one position to another within a single molecule. GO:0016869 intramolecular transferase activity, transferring amino groups biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016869 EC:5.4.3.- Catalysis of the transfer of an amino group from one position to another within a single molecule. GO:0016862 intramolecular oxidoreductase activity, interconverting keto- and enol-groups biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016862 EC:5.3.2.- intramolecular isomerase activity, interconverting keto- and enol-groups Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor, which is a keto- or an enol-group, are the same molecule, and no oxidized product appears. GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016863 EC:5.3.3.- intramolecular isomerase activity, transposing C=C bonds Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, one or more carbon-carbon double bonds in the molecule are rearranged, and no oxidized product appears. GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016864 EC:5.3.4.- intramolecular isomerase activity, transposing S-S bonds Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, one or more sulfur-sulfur bonds in the molecule are rearranged, and no oxidized product appears. GO:0016865 obsolete intramolecular oxidoreductase activity, other intramolecular oxidoreductases biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016865 intramolecular oxidoreductase activity, other intramolecular oxidoreductases|intramolecular isomerase activity, other intramolecular oxidoreductases OBSOLETE. A grouping term for intramolecular oxidoreductases that cannot be more accurately categorized. CHEBI:90553 1-dihexosyl-2,3-diacylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90553 GO:0016860 intramolecular oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016860 EC:5.3.-.-|Reactome:R-HSA-109998|RHEA:45752 intramolecular isomerase activity|intramolecular oxidoreductase activity, other intramolecular oxidoreductases Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, and no oxidized product appears. GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016861 EC:5.3.1.- intramolecular isomerase activity, interconverting aldoses and ketoses Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor, which is an aldose or a ketose, are the same molecule, and no oxidized product appears. GO:0002229 defense response to oomycetes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002229 Reactions triggered in response to the presence of oomycetes that act to protect the cell or organism. CHEBI:90550 monohexosyldiglyceride biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90550 CHEBI:90551 monohexosyldiradylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90551 GO:0002236 detection of misfolded protein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002236 The series of events in which a misfolded protein stimulus is received and converted into a molecular signal. GO:0002237 response to molecule of bacterial origin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002237 response to bacterium associated molecule|response to bacteria associated molecule|response to bacterial associated molecule Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin. GO:0002238 response to molecule of fungal origin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002238 response to fungus associated molecule Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of fungal origin such as chito-octamer oligosaccharide. GO:0002239 response to oomycetes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002239 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an oomycetes. GO:0002232 leukocyte chemotaxis involved in inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002232 immune cell chemotaxis during inflammatory response|leukocyte chemotaxis during inflammatory response|leucocyte chemotaxis during inflammatory response The movement of an immune cell in response to an external stimulus contributing to an inflammatory response. GO:0002233 leukocyte chemotaxis involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002233 leucocyte chemotaxis during immune response|immune cell chemotaxis during immune response The movement of an immune cell in response to an external stimulus a part of an immune response. GO:0002234 detection of endoplasmic reticulum overloading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002234 detection of ER overloading The series of events in which a stimulus generated by the accumulation of normal or misfolded proteins in the endoplasmic reticulum is received and converted into a molecular signal. GO:0002235 detection of unfolded protein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002235 The series of events in which an unfolded protein stimulus is received and converted into a molecular signal. GO:0002230 positive regulation of defense response to virus by host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002230 up regulation of antiviral response by host|upregulation of antiviral response by host|stimulation of antiviral response by host|up-regulation of antiviral response by host|positive regulation of antiviral response by host|activation of antiviral response by host Any host process that results in the promotion of antiviral immune response mechanisms, thereby limiting viral replication. GO:0002231 detection of oomycetes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002231 The series of events in which a stimulus from an oomycetes is received and converted into a molecular signal. GO:0016877 ligase activity, forming carbon-sulfur bonds biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016877 EC:6.2.-.- ligase activity, forming carbon-sulphur bonds Catalysis of the joining of two molecules via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. GO:0016878 acid-thiol ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016878 EC:6.2.1.- Catalysis of the joining of an acid and a thiol via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. GO:0016879 ligase activity, forming carbon-nitrogen bonds biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016879 EC:6.3.-.- other carbon-nitrogen ligase activity Catalysis of the joining of two molecules, or two groups within a single molecule, via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. GO:0016873 obsolete other isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016873 other isomerase activity OBSOLETE. A grouping term for isomerases that cannot be more accurately categorized. CHEBI:90546 medium-chain fatty acyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90546 GO:0016874 ligase activity biolink:MolecularActivity go-plus goslim_chembl|goslim_mouse|goslim_yeast|goslim_candida|goslim_pir|goslim_drosophila|goslim_aspergillus|goslim_metagenomics|goslim_generic http://purl.obolibrary.org/obo/GO_0016874 EC:6.-.-.- synthetase activity Catalysis of the joining of two molecules, or two groups within a single molecule, using the energy from the hydrolysis of ATP, a similar triphosphate, or a pH gradient. GO:0016875 ligase activity, forming carbon-oxygen bonds biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016875 EC:6.1.-.- Catalysis of the joining of two molecules via a carbon-oxygen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. GO:0016876 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016876 CHEBI:90549 1-monohexosyl-2,3-diacylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90549 GO:0016870 obsolete intramolecular transferase activity, transferring other groups biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016870 intramolecular transferase activity, transferring other groups OBSOLETE. A grouping term for intramolecular transferases that cannot be more accurately categorized. GO:0016871 cycloartenol synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016871 RHEA:21308|MetaCyc:CYCLOARTENOL-SYNTHASE-RXN|KEGG_REACTION:R03200|EC:5.4.99.8 2,3-epoxysqualene cycloartenol-cyclase activity|2,3-epoxysqualene--cycloartenol cyclase activity|(S)-2,3-epoxysqualene mutase (cyclizing, cycloartenol-forming)|2,3-oxidosqualene-cycloartenol cyclase activity|squalene-2,3-epoxide-cycloartenol cyclase activity|oxidosqualene:cycloartenol cyclase activity Catalysis of the reaction: (S)-2,3-epoxysqualene = cycloartenol. GO:0016872 intramolecular lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016872 EC:5.5.1.- The catalysis of certain rearrangements of a molecule to break or form a ring. GO:0002203 proteolysis by cytosolic proteases associated with antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002203 The hydrolysis of a peptide bond or bonds within a protein by cytosolic resident proteases during antigen processing and presentation. GO:0002204 somatic recombination of immunoglobulin genes involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002204 somatic recombination of antibody genes during immune response|somatic recombination of immunoglobulin genes during immune response The process in which immunoglobulin genes are formed through recombination of the germline genetic elements, also known as immunoglobulin gene segments, within a single locus following the induction of and contributing to an immune response. GO:0002205 somatic hypermutation of immunoglobulin genes involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002205 somatic hypermutation of antibody genes during immune response|somatic hypermutation of immunoglobulin genes during immune response Mutations occurring somatically that result in amino acid changes in the rearranged V regions of immunoglobulins following the induction of and contributing to an immune response. GO:0002206 gene conversion of immunoglobulin genes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002206 gene conversion of antibody genes The somatic process in which immunoglobulin genes are diversified through the mechanism of gene conversion. GO:0002200 somatic diversification of immune receptors biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002200 The somatic process allowing for the production of immune receptors whose specificity is not encoded in the germline genomic sequences. GO:0002201 somatic diversification of DSCAM-based immune receptors biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002201 The somatic process that results in the generation of sequence diversity of the DSCAM-based immune receptors of insects. GO:0002202 somatic diversification of variable lymphocyte receptors of jawless fish biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002202 The somatic process that results in the generation of sequence diversity of the variable lymphocyte receptors (VLR) of jawless fish. GO:0016848 carbon-halide lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016848 EC:4.5.-.- Catalysis of the breakage of a bond between carbon and any halogen atom. GO:0016849 phosphorus-oxygen lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016849 EC:4.6.-.- Catalysis of the cleavage of a phosphorus-oxygen bond by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. GO:0016844 strictosidine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016844 RHEA:15013|EC:4.3.3.2|MetaCyc:STRICTOSIDINE-SYNTHASE-RXN|KEGG_REACTION:R03738 3-alpha(S)-strictosidine tryptamine-lyase activity|strictosidine synthetase activity|STR activity|3-alpha(S)-strictosidine tryptamine-lyase (secologanin-forming) Catalysis of the reaction: 3alpha(S)-strictosidine + H(2)O = secologanin + tryptamine. GO:0016845 obsolete other carbon-nitrogen lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016845 other carbon-nitrogen lyase activity OBSOLETE. Catalysis of the cleavage of a carbon-nitrogen bond. Enzymes with this activity are 'miscellaneous' carbon-nitrogen lyases that cannot be grouped into one of the specific subclasses of the carbon-nitrogen lyases. GO:0016846 carbon-sulfur lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016846 EC:4.4.-.-|Reactome:R-HSA-1614567 carbon-sulphur lyase activity Catalysis of the elimination of hydrogen sulfide or substituted H2S. GO:0016847 1-aminocyclopropane-1-carboxylate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016847 KEGG_REACTION:R00179|MetaCyc:4.4.1.14-RXN|RHEA:21744|EC:4.4.1.14 L-vinylglycine deaminase activity|1-aminocyclopropane-1-carboxylic acid synthase activity|aminocyclopropanecarboxylic acid synthase activity|1-aminocyclopropane-1-carboxylate synthetase activity|S-adenosyl-L-methionine methylthioadenosine-lyase activity|L-VG deaminase activity|S-adenosyl-L-methionine methylthioadenosine-lyase (1-aminocyclopropane-1-carboxylate-forming)|aminocyclopropanecarboxylate synthase activity|ACC synthase activity|1-aminocyclopropanecarboxylate synthase activity Catalysis of the reaction: S-adenosyl-L-methionine(1+) = 1-aminocyclopropane-1-carboxylate + S-methyl-5'-thioadenosine + H(+). GO:0016840 carbon-nitrogen lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016840 EC:4.3.-.- other carbon-nitrogen lyase activity Catalysis of the release of ammonia or one of its derivatives, with the formation of a double bond or ring. Enzymes with this activity may catalyze the actual elimination of the ammonia, amine or amide, e.g. CH-CH(-NH-R) = C=CH- + NH2-R. Others, however, catalyze elimination of another component, e.g. water, which is followed by spontaneous reactions that lead to breakage of the C-N bond, e.g. L-serine ammonia-lyase (EC:4.3.1.17), so that the overall reaction is C(-OH)-CH(-NH2) = CH2-CO- + NH3, i.e. an elimination with rearrangement. The sub-subclasses of EC:4.3 are the ammonia-lyases (EC:4.3.1), lyases acting on amides, amidines, etc. (EC:4.3.2), the amine-lyases (EC:4.3.3), and other carbon-nitrogen lyases (EC:4.3.99). GO:0016841 ammonia-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016841 EC:4.3.1.- Catalysis of the release of ammonia by the cleavage of a carbon-nitrogen bond or the reverse reaction with ammonia as a substrate. GO:0016842 amidine-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016842 EC:4.3.2.- Catalysis of the release of amides or amidines by the cleavage of a carbon-nitrogen bond or the reverse reaction with an amide or amidine as a substrate. GO:0016843 amine-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016843 EC:4.3.3.- Catalysis of the release of amines by the cleavage of a carbon-nitrogen bond or the reverse reaction with an amine as a substrate. CHEBI:90575 dihexosyldiglyceride biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90575 CHEBI:90576 dihexosyldiradylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90576 CHEBI:90577 1-(9S,13S,12-oxophytodienoyl)-2-(7Z,10Z,13Z)-hexadecatrienoyl-3-(beta-D-galactosyl)-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90577 CHEBI:90578 2-(7Z,10Z,13Z)-hexadecatrienoyl-3-(beta-D-galactosyl)-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90578 GO:0002207 gene conversion of immunoglobulin genes involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002207 gene conversion of antibody genes during immune response|gene conversion of immunoglobulin genes during immune response The somatic process in which immunoglobulin genes are diversified through the mechanism of gene conversion following the induction of and contributing to an immune response. GO:0002208 somatic diversification of immunoglobulins involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002208 somatic diversification of immunoglobulins during immune response|somatic diversification of antibodies during immune response The somatic process that results in the generation of sequence diversity of immunoglobulins after induction, and contributes to an immune response. GO:0002209 behavioral defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002209 behavioural defense response A behavioral response seeking to protect an organism from an a perceived external threat to that organism. GO:0002214 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0002214 GO:0002215 defense response to nematode biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002215 physiological defense response to nematode A response to protect an organism from a directly detected or perceived external threat from a nematode or nematodes, which results in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack. GO:0002216 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0002216 GO:0002217 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0002217 GO:0002210 behavioral response to wounding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002210 behavioural response to wounding A behavioral response resulting from wounding. GO:0002211 behavioral defense response to insect biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002211 behavioural defense response to insect A behavioral response seeking to protect an organism from an a perceived external threat from an insect or insects to that organism. GO:0002212 behavioral defense response to nematode biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002212 behavioural defense response to nematode A behavioral response seeking to protect an organism from an a perceived external threat from a nematode or nematodes to that organism. GO:0002213 defense response to insect biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002213 physiological defense response to insect A response to protect an organism from a directly detected or perceived external threat from an insect or insects to that organism. CHEBI:41595 (+)-germacrene A biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_41595 GO:0016859 cis-trans isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016859 EC:5.2.-.- Catalysis of a reaction that interconverts cis and trans isomers. Atoms or groups are termed cis or trans to one another when they lie respectively on the same or on opposite sides of a reference plane identifiable as common among stereoisomers. GO:0016855 racemase and epimerase activity, acting on amino acids and derivatives biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016855 EC:5.1.1.- Catalysis of a reaction that alters the configuration of one or more chiral centers in an amino acid. GO:0016856 racemase and epimerase activity, acting on hydroxy acids and derivatives biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016856 EC:5.1.2.- Catalysis of a reaction that alters the configuration of one or more chiral centers in a hydroxy acid molecule. GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016857 EC:5.1.3.-|Reactome:R-HSA-6787677 Catalysis of a reaction that alters the configuration of one or more chiral centers in a carbohydrate molecule. GO:0016858 obsolete racemase and epimerase activity, acting on other compounds biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016858 racemase and epimerase activity, acting on other compounds OBSOLETE. Racemase and epimerase activity on compounds other than amino acids, hydroxy acids, carbohydrates or their derivatives. GO:0016851 magnesium chelatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016851 KEGG_REACTION:R03877|RHEA:13961|EC:6.6.1.1|MetaCyc:RXN1F-20 magnesium-chelatase activity|Mg-chelatase activity|magnesium-protoporphyrin chelatase activity|Mg-protoporphyrin IX magnesium-lyase activity|magnesium-protoporphyrin IX chelatase activity|protoporphyrin IX magnesium-chelatase activity|Mg-protoporphyrin IX magnesio-lyase activity|Mg-protoporphyrin IX chelatase activity|protoporphyrin IX Mg-chelatase activity Catalysis of the reaction: ATP + H(2)O + Mg(2+) + protoporphyrin IX = ADP + 2 H(+) + magnesium protoporphyrin IX + phosphate. GO:0016852 sirohydrochlorin cobaltochelatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016852 MetaCyc:4.99.1.3-RXN|RHEA:15893|EC:4.99.1.3 anaerobic cobalt chelatase activity|CbiXS|cobalt-sirohydrochlorin cobalt-lyase (sirohydrochlorin-forming)|CbiK|sirohydrochlorin cobalt-lyase activity|CbiX Catalysis of the reaction: sirohydrochlorin + Co2+ = cobalt-sirohydrochlorin + 2 H+. GO:0016853 isomerase activity biolink:MolecularActivity go-plus goslim_chembl|goslim_yeast|goslim_candida|goslim_pir|goslim_drosophila|goslim_aspergillus|goslim_metagenomics|goslim_generic http://purl.obolibrary.org/obo/GO_0016853 EC:5.-.-.-|Reactome:R-HSA-6787623 other isomerase activity Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5. GO:0016854 racemase and epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016854 EC:5.1.-.- racemase and epimerase activity, acting on other compounds Catalysis of a reaction that alters the configuration of one or more chiral centers in a molecule. GO:0016850 obsolete other lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016850 other lyase activity OBSOLETE. A grouping term for lyases that cannot be more accurately categorized. GO:0002218 activation of innate immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002218 Any process that initiates an innate immune response. Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. Examples of this process include activation of the hypersensitive response of Arabidopsis thaliana and activation of any NOD or TLR signaling pathway in vertebrate species. GO:0002219 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0002219 CHEBI:41582 D-pipecolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_41582 GO:0016826 hydrolase activity, acting on acid sulfur-nitrogen bonds biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016826 EC:3.10.-.- hydrolase activity, acting on acid sulphur-nitrogen bonds Catalysis of the hydrolysis of any acid sulfur-nitrogen bond. GO:0016827 hydrolase activity, acting on acid carbon-phosphorus bonds biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016827 EC:3.11.-.- Catalysis of the hydrolysis of any acid carbon-phosphorus bond. GO:0016828 hydrolase activity, acting on acid sulfur-sulfur bonds biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016828 EC:3.12.-.- hydrolase activity, acting on acid sulphur-sulphur bonds Catalysis of the hydrolysis of any acid sulfur-sulfur bond. GO:0016829 lyase activity biolink:MolecularActivity go-plus goslim_chembl|goslim_yeast|goslim_candida|goslim_pir|goslim_drosophila|goslim_aspergillus|goslim_metagenomics|goslim_generic http://purl.obolibrary.org/obo/GO_0016829 Reactome:R-HSA-6782895|Reactome:R-HSA-5696408|RHEA:34091|EC:4.-.-.- other lyase activity Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring. GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016822 EC:3.7.-.- Catalysis of the hydrolysis of any acid carbon-carbon bond. GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016823 EC:3.7.1.- Catalysis of the hydrolysis of any acid carbon-carbon bond in a ketonic substance, a substance containing a keto (C=O) group. GO:0016824 hydrolase activity, acting on acid halide bonds biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016824 EC:3.8.-.- Catalysis of the hydrolysis of any acid halide bond. GO:0016825 hydrolase activity, acting on acid phosphorus-nitrogen bonds biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016825 EC:3.9.-.- Catalysis of the hydrolysis of any acid phosphorus-nitrogen bond. GO:0016820 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016820 GO:0016821 obsolete hydrolase activity, acting on acid anhydrides, involved in cellular and subcellular movement biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016821 hydrolase activity, acting on acid anhydrides, involved in cellular and subcellular movement OBSOLETE. (Was not defined before being made obsolete). CHEBI:90598 L-aspartic acid alpha-methyl ester residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90598 CHEBI:90595 S-[(2E,6E)-farnesyl]-L-cysteino group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90595 CHEBI:90596 L-beta-isoaspartate residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90596 GO:0051203 peptidyl-aspartic acid reduction to form L-aspartyl aldehyde biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051203 RESID:AA0373 peptidyl-aspartic acid reduction to form L-aspartate-beta-semialdehyde|peptidyl-aspartic acid reduction to form L-beta-formylalanine The reduction of peptidyl-aspartic acid to form peptidyl-L-aspartyl aldehyde, as found photosystem II P680 chlorophyll A apoprotein. GO:0051204 protein insertion into mitochondrial membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051204 integral mitochondrial membrane protein localization|integral mitochondrial membrane protein positioning|protein-mitochondrion membrane insertion|protein insertion into mitochondrion membrane|localization of protein in mitochondrial membrane|positioning of protein in mitochondrial membrane|protein-mitochondrial membrane insertion The process that results in the incorporation of a protein into a mitochondrial membrane. GO:0051201 negative regulation of prosthetic group metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051201 downregulation of prosthetic group metabolic process|negative regulation of coenzyme and prosthetic group metabolic process|down regulation of prosthetic group metabolic process|inhibition of prosthetic group metabolic process|negative regulation of prosthetic group metabolism|down-regulation of prosthetic group metabolic process|negative regulation of coenzyme and prosthetic group metabolism Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a prosthetic group. GO:0051202 phytochromobilin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051202 phytochromobilin metabolism The chemical reactions and pathways involving phytochromobilin, the linear tetrapyrrole chromophore required for plant phytochrome photoactivity. GO:0051207 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051207 GO:0051208 sequestering of calcium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051208 retention of calcium ion (Ca2+)|calcium ion storage activity|storage of calcium ion (Ca2+)|negative regulation of calcium ion (Ca2+) transport|calcium ion (Ca2+) retention|sequestration of calcium ion (Ca2+)|calcium ion (Ca2+) storage|calcium ion (Ca2+) sequestering|calcium ion (Ca2+) sequestration|sequestering of calcium ion (Ca2+) The process of binding or confining calcium ions such that they are separated from other components of a biological system. GO:0051205 protein insertion into membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051205 integral membrane protein localization|membrane protein positioning|protein-membrane insertion|integral membrane protein positioning|membrane protein localization The process that results in the incorporation of a protein into a biological membrane. Incorporation in this context means having some part or covalently attached group that is inserted into the the hydrophobic region of one or both bilayers. GO:0051206 silicate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051206 silicate metabolism The chemical reactions and pathways involving silicates, the salts of silicic acids. Silicates are usually composed of silicon and oxygen (Si[x]O[y]), one or more metals, and possibly hydrogen. Types of silicate include unisilicates, metasilicates and hydrous silicates. GO:0051209 release of sequestered calcium ion into cytosol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051209 calcium ion (Ca2+) mobilization|release of stored calcium ion (Ca2+) into cytoplasm|release of sequestered calcium ion (Ca2+)|release of stored calcium ion (Ca2+) into cytosol|release of stored calcium ion (Ca2+)|cytoplasmic release of stored calcium ion (Ca2+)|calcium mobilization|cytosolic release of stored calcium ion (Ca2+)|cytoplasmic release of sequestered calcium ion (Ca2+)|release of sequestered calcium ion into cytoplasm|cytosolic release of sequestered calcium ion (Ca2+) The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the cytosolic compartment. GO:0016837 carbon-oxygen lyase activity, acting on polysaccharides biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016837 EC:4.2.2.- Catalysis of the cleavage of a carbon-oxygen bond by the elimination of an alcohol from a polysaccharide. GO:0016838 carbon-oxygen lyase activity, acting on phosphates biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016838 EC:4.2.3.- Catalysis of the cleavage of a carbon-oxygen bond by elimination of a phosphate. GO:0016839 obsolete other carbon-oxygen lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016839 other carbon-oxygen lyase activity OBSOLETE. Catalysis of the cleavage of a carbon-oxygen bond. Enzymes with this activity are 'miscellaneous' carbon-oxygen lyases that cannot be grouped into one of the specific subclasses of the carbon-oxygen lyases. GO:0016833 oxo-acid-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016833 EC:4.1.3.- oxoacid lyase activity|oxo-acid lyase activity Catalysis of the cleavage of a C-C bond by other means than by hydrolysis or oxidation, of a 3-hydroxy acid. GO:0016834 obsolete other carbon-carbon lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016834 other carbon-carbon lyase activity OBSOLETE. A grouping term for carbon-carbon lyases that cannot be more accurately categorized. GO:0016835 carbon-oxygen lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016835 EC:4.2.-.- other carbon-oxygen lyase activity Catalysis of the breakage of a carbon-oxygen bond. GO:0016836 hydro-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016836 EC:4.2.1.-|Reactome:R-HSA-9014627 Catalysis of the cleavage of a carbon-oxygen bond by elimination of water. GO:0016830 carbon-carbon lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016830 EC:4.1.-.-|Reactome:R-HSA-389611|RHEA:25355 other carbon-carbon lyase activity Catalysis of the cleavage of C-C bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. GO:0016831 carboxy-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016831 Reactome:R-HSA-6814165|Reactome:R-HSA-6787757|Reactome:R-HSA-71223|EC:4.1.1.- decarboxylase activity Catalysis of the nonhydrolytic addition or removal of a carboxyl group to or from a compound. GO:0016832 aldehyde-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016832 EC:4.1.2.- aldolase activity Catalysis of the cleavage of a C-C bond in a molecule containing a hydroxyl group and a carbonyl group to form two smaller molecules, each being an aldehyde or a ketone. CHEBI:90582 hexadecatrienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90582 GO:0051200 positive regulation of prosthetic group metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051200 positive regulation of coenzyme and prosthetic group metabolism|upregulation of prosthetic group metabolic process|stimulation of prosthetic group metabolic process|positive regulation of prosthetic group metabolism|up-regulation of prosthetic group metabolic process|activation of prosthetic group metabolic process|positive regulation of coenzyme and prosthetic group metabolic process|up regulation of prosthetic group metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a prosthetic group. GO:0051214 RNAi-mediated antiviral immunity against RNA virus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051214 PMID:17693253 RNA virus induced gene silencing|RNA VIGS|RNA virus-induced gene silencing Gene silencing induced by RNA viruses leading to a sequence-specific degradation of target mRNAs or post-transcriptional gene silencing. In plants, DCL4 is the primary Dicer to detect RNA viruses. GO:0051215 RNAi-mediated antiviral immunity against DNA virus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051215 DNA VIGS|DNA virus-induced gene silencing|DNA virus induced gene silencing Gene silencing induced by DNA viruses leading to a sequence-specific degradation of target mRNAs or post-transcriptional gene silencing. In plants, DCL3 is the primary Dicer to detect DNA viruses. GO:0051212 vanadium ion binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051212 Interacting selectively and non-covalently with vanadium (V) ions. GO:0051213 dioxygenase activity biolink:MolecularActivity go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0051213 Reactome:R-HSA-112125|Reactome:R-HSA-112121|Reactome:R-HSA-112124|Reactome:R-HSA-112120 Catalysis of an oxidation-reduction (redox) reaction in which both atoms of oxygen from one molecule of O2 are incorporated into the (reduced) product(s) of the reaction. The two atoms of oxygen may be distributed between two different products. GO:0051218 tungsten incorporation via L-selenocysteinyl tungsten bis(molybdopterin guanine dinucleotide) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051218 RESID:AA02376 The incorporation of tungsten into a protein via L-selenocysteinyl tungsten bis(molybdopterin guanine dinucleotide). GO:0051219 phosphoprotein binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0051219 phosphorylated protein binding Interacting selectively and non-covalently with a phosphorylated protein. GO:0051216 cartilage development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051216 Wikipedia:Chondrogenesis chondrogenesis|cartilage organ development|cartilage biogenesis|cartilage element development|cartilage biosynthesis|cartilage formation The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. GO:0051217 molybdenum incorporation via L-aspartyl molybdenum bis(molybdopterin guanine dinucleotide) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051217 RESID:AA0375 The incorporation of molybdenum into a protein via L-aspartyl molybdenum bis(molybdopterin guanine dinucleotide). GO:0016808 obsolete proprotein convertase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016808 proprotein convertase activity OBSOLETE. Was not defined before being made obsolete. GO:0016809 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016809 GO:0016804 obsolete prolyl aminopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016804 proline aminopeptidase|cytosol aminopeptidase V|prolyl aminopeptidase activity|Pro-X aminopeptidase activity|proline iminopeptidase activity OBSOLETE. Catalysis of the release of a N-terminal proline from a peptide. GO:0016805 dipeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016805 EC:3.4.13.-|Reactome:R-HSA-9026771|MetaCyc:3.4.13.18-RXN|Reactome:R-HSA-5433067|EC:3.4.13.18|MetaCyc:3.4.13.21-RXN|EC:3.4.13.21|Reactome:R-HSA-266012|Reactome:R-HSA-5693783 cytosolic dipeptidase activity Catalysis of the hydrolysis of a dipeptide. GO:0016806 obsolete dipeptidyl-peptidase and tripeptidyl-peptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016806 EC:3.4.14.- dipeptidyl-peptidase and tripeptidyl-peptidase activity OBSOLETE. Catalysis of the hydrolysis of N-terminal di- or tripeptides from a polypeptide chain. GO:0016807 cysteine-type carboxypeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016807 MetaCyc:3.4.18.1-RXN|EC:3.4.18.- Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile. GO:0016800 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016800 GO:0016801 hydrolase activity, acting on ether bonds biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016801 EC:3.3.-.- Catalysis of the hydrolysis of any ether or thioether bond, -O- or -S- respectively. GO:0016802 trialkylsulfonium hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016802 EC:3.3.1.- trialkylsulphonium hydrolase activity|thioether hydrolase activity Catalysis of the hydrolysis of a thioether bond, -S-. GO:0016803 ether hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016803 Reactome:R-HSA-8874435|EC:3.3.2.- Catalysis of the hydrolysis of an ether bond, -O-. GO:0051210 isotropic cell growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051210 uniform cell growth The process in which a cell irreversibly increases in size uniformly in all directions. In general, a rounded cell morphology reflects isotropic cell growth. GO:0051211 anisotropic cell growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051211 non-isotropic cell growth The process in which a cell irreversibly increases in size in one or more axes, where the growth rate varies according to the direction of growth. Growth may be limited to a particular axis, axes, or to particular locations on the surface of the cell. UBERON:0008522 nasal muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008522 muscle of nose Any muscle organ that is part of an nose. GO:0051225 spindle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051225 bipolar spindle biosynthesis|spindle biosynthesis|spindle formation|bipolar spindle formation The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart. GO:0051226 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051226 GO:0051223 regulation of protein transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051223 Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0051224 negative regulation of protein transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051224 downregulation of protein transport|down-regulation of protein transport|inhibition of protein transport|down regulation of protein transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0051229 meiotic spindle disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051229 meiotic spindle degradation|spindle disassembly during meiosis|meiotic spindle breakdown|spindle breakdown during meiosis|meiotic spindle catabolism|spindle degradation during meiosis The controlled breakdown of the spindle during a meiotic cell cycle. GO:0051227 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051227 GO:0051228 mitotic spindle disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051228 spindle disassembly during mitosis|mitotic spindle degradation|mitotic spindle breakdown|spindle breakdown during mitosis|spindle degradation during mitosis|mitotic spindle catabolism The controlled breakdown of the spindle during a mitotic cell cycle. GO:0016819 hydrolase activity, acting on acid anhydrides, in sulfonyl-containing anhydrides biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016819 EC:3.6.2.- hydrolase activity, acting on acid anhydrides, in sulphonyl-containing anhydrides Catalysis of the hydrolysis of any acid anhydride which contains a sulfonyl group, -SO2-. GO:0016815 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in nitriles biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016815 EC:3.5.5.- Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a nitrile, a compound containing the cyano radical, -CN. GO:0016816 obsolete hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in other compounds biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016816 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in other compounds OBSOLETE. Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in substances other than amides, amidines and nitriles. CHEBI:41550 fluoroform biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_41550 GO:0016817 hydrolase activity, acting on acid anhydrides biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016817 EC:3.6.-.- hydrolase activity, acting on acid anhydrides, involved in cellular and subcellular movement Catalysis of the hydrolysis of any acid anhydride. GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016818 EC:3.6.1.- Catalysis of the hydrolysis of any acid anhydride which contains phosphorus. GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016811 EC:3.5.1.-|Reactome:R-HSA-9673053|Reactome:R-HSA-9673054 Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amide. GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016812 EC:3.5.2.-|Reactome:R-HSA-70906 Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amide. GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016813 EC:3.5.3.- Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amidine, a compound of the form R-C(=NH)-NH2. GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016814 EC:3.5.4.- Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2. GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds biolink:MolecularActivity go-plus goslim_generic|goslim_chembl|goslim_drosophila http://purl.obolibrary.org/obo/GO_0016810 EC:3.5.-.-|RHEA:45456|Reactome:R-HSA-6803753 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in other compounds Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds. GO:0051221 tungsten incorporation into metallo-sulfur cluster biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051221 tungsten incorporation into metallo-sulphur cluster The incorporation of tungsten into a metallo-sulfur cluster. GO:0051222 positive regulation of protein transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051222 up regulation of protein transport|activation of protein transport|stimulation of protein transport|up-regulation of protein transport|upregulation of protein transport Any process that activates or increases the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0051220 cytoplasmic sequestering of protein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051220 cytoplasmic storage of protein|retention of protein in cytoplasm|storage of protein in cytoplasm|cytoplasmic retention of protein|maintenance of protein location in cytoplasm|sequestration of protein in cytoplasm|cytoplasmic sequestration of protein|sequestering of protein in cytoplasm The selective interaction of a protein with specific molecules in the cytoplasm, thereby inhibiting its transport into other areas of the cell. CHEBI:145394 1,2-diacyl-sn-glycero-3-phosphoglycerol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_145394 CHEBI:145397 1-oleoyl-2-acyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_145397 GO:0002287 alpha-beta T cell activation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002287 alpha-beta T lymphocyte activation during immune response|alpha-beta T-cell activation during immune response|alpha-beta T-lymphocyte activation during immune response|alpha-beta T cell activation during immune response The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response. GO:0002288 NK T cell activation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002288 natural killer T lymphocyte activation during immune response|NK T-cell activation during immune response|NK T-lymphocyte activation during immune response|natural killer T-cell activation during immune response|NK T cell activation during immune response|natural killer T-lymphocyte activation during immune response|NK T lymphocyte activation during immune response The change in morphology and behavior of a mature or immature natural killer T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response. GO:0002289 NK T cell proliferation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002289 NK T-cell proliferation during immune response|natural killer T lymphocyte proliferation during immune response|NK T cell proliferation during immune response|NK T lymphocyte proliferation during immune response|natural killer T-lymphocyte proliferation during immune response|natural killer T-cell proliferation during immune response|NK T-lymphocyte proliferation during immune response The expansion of a NK T cell population by cell division as part of an immune response. GO:0002283 neutrophil activation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002283 neutrophil activation during immune response The change in morphology and behavior of a neutrophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. GO:0002284 myeloid dendritic cell differentiation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002284 myeloid dendritic cell differentiation during immune response The process in which an immature myeloid dendritic cell acquires the specialized features of a mature myeloid dendritic cell as part of an immune response. GO:0002285 lymphocyte activation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002285 lymphocyte activation during immune response A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. GO:0002286 T cell activation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002286 T lymphocyte activation during immune response|T-cell activation during immune response|T-lymphocyte activation during immune response|T cell activation during immune response The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response. GO:0099191 trans-synaptic signaling by BDNF biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099191 trans-synaptic signaling by brain-derived neurotrophic factor Cell-cell signaling between presynapse and postsynapse mediated by brain-derived neurotrophic factor (BDNF) crossing the synaptic cleft. OBO:chebi#is_substituent_group_from is substituent group from biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/chebi#is_substituent_group_from GO:0099192 cerebellar Golgi cell to granule cell synapse biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099192 A synapse formed by a cerebellar Golgi cell synapsing on to a cerebellar granule cell. GO:0002280 monocyte activation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002280 monocyte activation during immune response The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. GO:0002281 macrophage activation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002281 macrophage polarization involved in immune response|macrophage activation during immune response A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. GO:0099190 postsynaptic spectrin-associated cytoskeleton organization biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0099190 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of spectrin-associated cytoskeleton and associated proteins in the postsynapse. GO:0002282 microglial cell activation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002282 microglial cell activation during immune response The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. GO:0002298 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002298 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation during immune response|CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation during immune response|CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation during immune response|CD4-positive, CD25-positive, alpha-beta T cell development involved in immune response The process in which an antigenically naive CD4-positive, alpha-beta T cell acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell as part of an immune response. GO:0002299 alpha-beta intraepithelial T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002299 alpha-beta intraepithelial T cell development|alpha-beta intraepithelial T lymphocyte differentiation|alpha-beta intraepithelial T-cell differentiation|alpha-beta intraepithelial T-lymphocyte differentiation The process in which a precursor cell type acquires the specialized features of an alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways. GO:0002294 CD4-positive, alpha-beta T cell differentiation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002294 CD4-positive, alpha-beta T cell differentiation during immune response|CD4-positive, alpha-beta T lymphocyte differentiation during immune response|CD4-positive, alpha-beta T cell development involved in immune response|CD4-positive, alpha-beta T-lymphocyte differentiation during immune response|CD4-positive, alpha-beta T-cell differentiation during immune response The process in which an antigenically naive CD4-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells. GO:0002295 T-helper cell lineage commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002295 Thp lineage commitment|Th0 lineage commitment|T-helper cell fate commitment The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper cell, a CD4-positive, alpha-beta T cell specialized to promote various immunological processes. GO:0002296 T-helper 1 cell lineage commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002296 Th1 fate commitment|Th1 cell lineage commitment|T-helper 1 cell fate commitment The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 1 cell, a CD4-positive, alpha-beta T cell specialized to promote immunological processes often associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis. GO:0002297 T-helper 2 cell lineage commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002297 Th2 fate commitment|T-helper 2 cell fate commitment The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 2 cell, a CD4-positive, alpha-beta T cell specialized to promote immunological processes often associated with resistance to extracellular organisms such as helminths, enhanced production of particular antibody isotypes, and pathological conditions such as allergy. GO:0002290 gamma-delta T cell activation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002290 gamma-delta T-cell activation during immune response|gamma-delta T-lymphocyte activation during immune response|gamma-delta T cell activation during immune response|gamma-delta T lymphocyte activation during immune response The change in morphology and behavior of a gamma-delta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response. GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002291 T lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell|T-lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell|T-cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell The change in morphology and behavior of a mature or immature T cell resulting from exposure to an antigen for which its T cell receptor is specific bound to an MHC molecule on an antigen presenting cell, leading to the initiation or perpetuation of an immune response. GO:0002292 T cell differentiation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002292 T-cell differentiation during immune response|T cell development involved in immune response|T lymphocyte differentiation during immune response|T cell differentiation during immune response|T-lymphocyte differentiation during immune response The process in which an antigenically naive T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells. GO:0002293 alpha-beta T cell differentiation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002293 alpha-beta T-cell differentiation during immune response|alpha-beta T cell development involved in immune response|alpha-beta T cell differentiation during immune response|alpha-beta T lymphocyte differentiation during immune response|alpha-beta T-lymphocyte differentiation during immune response The process in which an antigenically naive alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell during an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells. GO:0002269 leukocyte activation involved in inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002269 leukocyte activation during inflammatory response|immune cell activation during inflammatory response A change in the morphology or behavior of a leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an inflammatory response. GO:0002265 astrocyte activation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002265 astrocyte activation during immune response A change in the morphology or behavior of an astrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. GO:0002266 follicular dendritic cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002266 A change in the morphology or behavior of a follicular dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand. GO:0002267 follicular dendritic cell activation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002267 follicular dendritic cell activation during immune response A change in the morphology or behavior of a follicular dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. GO:0002268 follicular dendritic cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002268 The process in which a relatively unspecialized precursor cell acquires the specialized features of a follicular dendritic cell. GO:0002261 mucosal lymphocyte homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002261 The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within the mucosal tissue of an organism is stable over time in the absence of an outside stimulus. GO:0002262 myeloid cell homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002262 The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. GO:0002263 cell activation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002263 cell activation during immune response A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. GO:0002264 endothelial cell activation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002264 endothelial cell activation during immune response A change in the morphology or behavior of an endothelial cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. GO:0002260 lymphocyte homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002260 The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus. CHEBI:90517 methyl L-leucinato group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90517 CHEBI:90513 alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-Cer(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90513 CHEBI:90514 1-(beta-D-galactosyl)-monododecanoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90514 CHEBI:90515 3-(beta-D-galactosyl)-monododecanoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90515 CHEBI:90516 L-leucinate residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90516 CHEBI:90510 S-[(2E,6E)-farnesyl]-L-cysteinate residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90510 CHEBI:90511 S-[(2E,6E)-farnesyl]-L-cysteine methyl ester residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90511 CHEBI:90512 alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-Cer(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90512 GO:0002276 basophil activation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002276 basophil activation during immune response A change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response. GO:0002277 myeloid dendritic cell activation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002277 myeloid dendritic cell activation during immune response The change in morphology and behavior of a myeloid dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. GO:0002278 eosinophil activation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002278 eosinophil activation during immune response The change in morphology and behavior of a eosinophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. GO:0002279 mast cell activation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002279 mast cell activation during immune response The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response. GO:0002272 plasmacytoid dendritic cell differentiation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002272 plasmacytoid dendritic cell differentiation during immune response The process in which an immature plasmacytoid dendritic cell acquires the specialized features of a mature plasmacytoid dendritic cell contributing to an immune response. GO:0002273 plasmacytoid dendritic cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002273 The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a plasmacytoid dendritic cell. GO:0002274 myeloid leukocyte activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002274 myeloid leucocyte activation A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. GO:0002275 myeloid cell activation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002275 myeloid cell activation during immune response A change in the morphology or behavior of a myeloid cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. GO:0002270 plasmacytoid dendritic cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002270 A change in the morphology or behavior of a plasmacytoid dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand. GO:0002271 plasmacytoid dendritic cell activation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002271 plasmacytoid dendritic cell activation during immune response A change in the morphology or behavior of a plasmacytoid dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. CHEBI:145353 3beta-hydroxy-4alpha-formyl-4beta-methylsteroid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_145353 CHEBI:90506 1,2-di-(9Z,12Z-octadecadienoyl)-3-(beta-D-galactosyl)-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90506 CHEBI:90507 1-(9Z-octadecenoyl)-2-hexadecanoyl-3-beta-D-galactosyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90507 CHEBI:90501 alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90501 GO:0002247 clearance of damaged tissue involved in inflammatory response wound healing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002247 clearance of damaged tissue during inflammatory response The series of events leading to removal of necrotic debris that contribute to an inflammatory response. GO:0002248 connective tissue replacement involved in inflammatory response wound healing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002248 fibrosis during inflammatory response|connective tissue replacement during inflammatory response The series of events leading to growth of connective tissue when loss of tissues that are incapable of regeneration occurs, or when fibrinous exudate cannot be adequately cleared that contribute to an inflammatory response. GO:0002249 lymphocyte anergy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002249 Any process contributing to lymphocyte anergy, a state of functional inactivation. GO:0002243 detection of parasitic plant biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002243 The series of events in which a stimulus from a parasitic plant is received and converted into a molecular signal. GO:0002244 hematopoietic progenitor cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002244 haematopoietic progenitor cell differentiation|hemopoietic progenitor cell differentiation|haemopoietic progenitor cell differentiation The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells. GO:0002245 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0002245 GO:0002246 wound healing involved in inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002246 inflammatory response wound healing|healing during inflammatory response The series of events that restore integrity to damaged tissue that contribute to an inflammatory response. GO:0002240 response to molecule of oomycetes origin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002240 response to oomycetes associated molecule Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of oomycetes origin. CHEBI:89540 methyl propenyl ketone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_89540 GO:0002241 response to parasitic plant biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002241 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a parasitic plant. GO:0002242 defense response to parasitic plant biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002242 Reactions triggered in response to the presence of a parasitic plant that act to protect an organism. GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016888 EC:3.1.21.-|Reactome:R-HSA-912368 endodeoxyribonuclease activity, producing 5' phosphomonoesters Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters. GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016889 EC:3.1.22.- endodeoxyribonuclease activity, producing other than 5'-phosphomonoesters Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 3'-phosphomonoesters. GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016884 EC:6.3.5.- Catalysis of the transfer of the amide nitrogen of glutamine to a substrate. Usually composed of two subunits or domains, one that first hydrolyzes glutamine, and then transfers the resulting ammonia to the second subunit (or domain), where it acts as a source of nitrogen. GO:0016885 ligase activity, forming carbon-carbon bonds biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016885 EC:6.4.-.- Catalysis of the joining of two molecules via a carbon-carbon bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. GO:0016886 ligase activity, forming phosphoric ester bonds biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016886 EC:6.5.-.- Catalysis of the joining of two molecules, or two groups within a single molecule, via a phosphoric ester bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. GO:0016887 ATPase activity biolink:MolecularActivity go-plus goslim_drosophila|goslim_generic|goslim_chembl|goslim_yeast http://purl.obolibrary.org/obo/GO_0016887 RHEA:13065|Reactome:R-HSA-6814678|Reactome:R-HSA-6814683|Reactome:R-HSA-6814670|Reactome:R-HSA-5694425|Reactome:R-HSA-8939203|Reactome:R-HSA-9609860|Reactome:R-HSA-6809015|Reactome:R-HSA-5618093|MetaCyc:ADENOSINETRIPHOSPHATASE-RXN|Reactome:R-HSA-5654989|Reactome:R-HSA-72139|Reactome:R-HSA-917693|Reactome:R-HSA-416985|Reactome:R-HSA-3371422|Reactome:R-HSA-8847638|Reactome:R-HSA-8868658|Reactome:R-HSA-6811422|Reactome:R-HSA-159101|Reactome:R-HSA-9706399|Reactome:R-HSA-9038161|Reactome:R-HSA-9668415 ATP monophosphatase activity|adenosine 5'-triphosphatase activity|adenosinetriphosphatase activity|adenosine triphosphatase activity|ATP hydrolase activity|ATPase activity, coupled|ATP phosphohydrolase activity|(Ca2+ + Mg2+)-ATPase A molecular function that uses ATP hydrolysis as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. GO:0016880 acid-ammonia (or amide) ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016880 EC:6.3.1.- amide synthase activity Catalysis of the ligation of an acid to ammonia (NH3) or an amide via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. GO:0016881 acid-amino acid ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016881 EC:6.3.2.- peptide synthase activity Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. GO:0016882 cyclo-ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016882 EC:6.3.3.- Catalysis of the joining of two groups within a single molecule via a carbon-nitrogen bond, forming heterocyclic ring, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. GO:0016883 obsolete other carbon-nitrogen ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016883 other carbon-nitrogen ligase activity OBSOLETE. A grouping term for carbon-nitrogen ligases that cannot be more accurately categorized. GO:0002258 positive regulation of kinin cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002258 up-regulation of kinin cascade|upregulation of kinin cascade|up regulation of kinin cascade|activation of kinin cascade|stimulation of kinin cascade Any process that activates or increases the frequency, rate, or extent of the kinin cascade. GO:0002259 endothelial cell activation within high endothelial venule involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002259 endothelial cell activation within high endothelial venule during immune response A change in the morphology or behavior of an endothelial cell within a high endothelial venule resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. GO:0002254 kinin cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002254 A series of reactions that takes place outside the cell that occur as a result of by-products of tissue damage, including collagen, cartilage, and basement membrane. The ultimate product of the kinin cascade include kallidin and bradykinin, agents known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability. GO:0002255 tissue kallikrein-kinin cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002255 glandular kallikrein-kinin cascade A series of reactions that takes place outside the cell initiated by the action of tissue (glandular) kallikreins on low molecular weight kininogen in response to tissue damage. Tissue kallikreins are present in glandular tissues and their fluids, such as the salivary glands, sweat glands, pancreas, and kidney. The ultimate products of the tissue kallikrein-kinin cascade include kallidin and bradykinin, agents known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability. GO:0002256 regulation of kinin cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002256 Any process that modulates the frequency, rate, or extent of the kinin cascade. GO:0002257 negative regulation of kinin cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002257 inhibition of kinin cascade|down regulation of kinin cascade|downregulation of kinin cascade|down-regulation of kinin cascade Any process that stops, prevents, or reduces the frequency, rate, or extent of the kinin cascade. GO:0002250 adaptive immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002250 Wikipedia:Adaptive_immune_system acquired immune response|immune memory response An immune response mediated by cells expressing specific receptors for antigen produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory). GO:0002251 organ or tissue specific immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002251 immune response in organ or tissue An immune response taking place in an organ or tissues such as the liver, brain, mucosa, or nervous system tissues. GO:0002252 immune effector process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002252 Any process of the immune system that can potentially contribute to an immune response. GO:0002253 activation of immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002253 Any process that initiates an immune response. CHEBI:65585 carnosic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65585 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016899 EC:1.1.3.- Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces an oxygen molecule. GO:0016895 exodeoxyribonuclease activity, producing 5'-phosphomonoesters biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016895 EC:3.1.11.- exodeoxyribonuclease activity, producing 5' phosphomonoesters|exonuclease VIII activity Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters. GO:0016896 exoribonuclease activity, producing 5'-phosphomonoesters biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016896 Reactome:R-HSA-429860|EC:3.1.13.- exoribonuclease activity, producing 5' phosphomonoesters Catalysis of the hydrolysis of ester linkages within ribonucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters. GO:0016897 exoribonuclease activity, producing 3'-phosphomonoesters biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016897 EC:3.1.14.- Catalysis of the hydrolysis of ester linkages within ribonucleic acids by removing nucleotide residues from the 3' or 5' end to yield 3' phosphomonoesters. GO:0016898 oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016898 EC:1.1.2.- Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces a cytochrome molecule. GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016891 EC:3.1.26.- Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters. GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016892 EC:3.1.27.- endoribonuclease activity, producing other than 5'-phosphomonoesters Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 3'-phosphomonoesters. GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016893 EC:3.1.30.- 5'-endonuclease activity|endoribonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 5'-phosphomonoesters. GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016894 EC:3.1.31.- 3'-endonuclease activity|endoribonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 3'-phosphomonoesters. OIO:SubsetProperty subset_property biolink:OntologyClass go-plus http://www.geneontology.org/formats/oboInOwl#SubsetProperty GO:0016890 site-specific endodeoxyribonuclease activity, specific for altered base biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016890 EC:3.1.25.- Catalysis of the hydrolysis of ester linkages at specific sites within a deoxyribonucleic acid molecule by creating internal breaks. CHEBI:9937 vasopressin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_9937 CHEBI:16517 cyclotriphosphoric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16517 CHEBI:16515 3-ADP-glyceric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16515 CHEBI:9907 ursodeoxycholic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_9907 CHEBI:16516 2'-deoxyribonucleoside triphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16516 CHEBI:16513 hydroxymalonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16513 CHEBI:16514 4',5,7-trihydroxy-3'-methoxyflavone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16514 CHEBI:16511 N-acetyl-D-glucosaminyl-1-diphospho-ditrans,polycis-undecaprenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16511 CHEBI:16512 (S)-N-methylcanadine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16512 CHEBI:16510 3-hydroxypropionate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16510 CHEBI:497734 L-thialysine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_497734 CHEBI:16508 cis,cis-muconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16508 CHEBI:16509 1,4-benzoquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16509 CHEBI:16506 N-acetyl-beta-D-glucosaminyl-(1->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16506 CHEBI:16507 1D-myo-inositol 1,2,4,5,6-pentakisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16507 CHEBI:16504 monodehydro-L-ascorbic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16504 CHEBI:16505 dihydrostreptomycin 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16505 CHEBI:16503 selane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16503 CHEBI:16500 1-phosphatidyl-1D-myo-inositol 5-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16500 CHEBI:16501 L-arabinonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16501 CHEBI:9973 vibriobactin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_9973 NCBITaxon:314295 Hominoidea organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_314295 apes|ape UBERON:0008193 pneumatized bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008193 pneumatic bone|hollow bone|os pneumaticum A bone that is hollow or contains many air cells, such as the mastoid process of the temporal bone[TMD]. NCBITaxon:314293 Simiiformes organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_314293 Anthropoidea UBERON:0008196 muscle of pectoral girdle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008196 pectoral girdle muscle|muscle of shoulder girdle Any muscle organ that is part of a pectoral girdle region. GO:0075324 negative regulation of oomycete sporangium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075324 Any process that stops, prevents, or reduces the frequency, rate or extent of oomycete sporangium development, a process that leads to the formation of oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiate, through specialized cleavage vesicles, into between 10 and 30 zoospores, which is laterally flagellated. GO:0051357 peptide cross-linking via 3-(2-methylthio)ethyl-6-(4-hydroxybenzylidene)-5-iminopiperazin-2-one biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051357 RESID:AA0377 biosynthetic process of protein-protein cross-link via L-methionyl-L-tyrosyl-2-keto-5-iminopiperazine|biosynthesis of protein-protein cross-link via L-methionyl-L-tyrosyl-2-keto-5-iminopiperazine The formation of a 2-keto-5-iminopiperazine protein chromophore cross-link from the alpha-amino nitrogen of residue n, a methionine, to the alpha-carboxyl carbon of residue n+1, a tyrosine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+2. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons. GO:0075325 spore dispersal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075325 spore dispersal on or near host during symbiotic interaction|active spore dispersal on or near host during symbiotic interaction|passive spore dispersal on or near host|active spore dispersal on or near host|spore dispersal on or near host Any process in which an organism disseminates its spores. GO:0051358 peptide cross-linking via 2-imino-glutamic acid 5-imidazolinone glycine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051358 RESID:AA0378 biosynthesis of protein-protein cross-link via 2-imino-glutamic acid 5-imidazolinone glycine|biosynthetic process of protein-protein cross-link via 2-imino-glutamic acid 5-imidazolinone glycine The formation of the non-fluorescent protein chromophore cross-link from the alpha-carboxyl carbon of residue n, a glutamic acid, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons. This modification is found in the GFP-like non-fluorescent red chromoprotein from the sea anemone Radianthus macrodactylus. GO:0051355 proprioception involved in equilibrioception biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051355 perception of orientation with respect to gravity by proprioception|proprioception during equilibrioception|equilibrioception by proprioception The series of events contributing to equilibrioception by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception plays an important role in the ability of an organism to perceive its orientation with respect to gravity. GO:0075326 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075326 GO:0051356 visual perception involved in equilibrioception biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051356 equilibrioception by visual perception|visual perception during equilibrioception|perception of orientation with respect to gravity by visual perception The series of events during equilibrioception required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual input plays an important role in the ability of an organism to perceive its orientation with respect to gravity. GO:0075327 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0075327 GO:0075328 formation of arbuscule for nutrient acquisition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075328 formation by symbiont of arbuscule for nutrient acquisition from host The assembly of an arbuscule, a fine, tree-like hyphal symbiont structure projected into the host cell for the purpose of obtaining nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075329 regulation of arbuscule formation for nutrient acquisition from host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075329 Any process that modulates the frequency, rate or extent of symbiont arbuscule formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051359 peptide cross-linking via 2-imino-methionine 5-imidazolinone glycine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051359 RESID:AA0379 biosynthetic process of protein-protein cross-link via 2-imino-methionine 5-imidazolinone glycine|biosynthesis of protein-protein cross-link via 2-imino-methionine 5-imidazolinone glycine The formation of the fluorescent protein FP611 chromophore cross-link from the alpha-carboxyl carbon of residue n, a methionine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons. This modification is found in the GFP-like fluorescent chromoprotein from the sea anemone Entacmaea quadricolor. GO:2000742 regulation of anterior head development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000742 Any process that modulates the frequency, rate or extent of anterior head development. GO:2000743 negative regulation of anterior head development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000743 Any process that stops, prevents or reduces the frequency, rate or extent of anterior head development. GO:2000744 positive regulation of anterior head development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000744 Any process that activates or increases the frequency, rate or extent of anterior head development. GO:2000745 obsolete positive regulation of transcription from RNA polymerase III promoter involved in smooth muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000745 activation of transcription from RNA polymerase III promoter of nonstriated muscle cell differentiation|up-regulation of transcription from RNA polymerase III promoter of nonstriated muscle cell differentiation|stimulation of transcription from RNA polymerase III promoter of nonstriated muscle cell differentiation|upregulation of transcription from RNA polymerase III promoter of smooth muscle cell differentiation|positive regulation of transcription from Pol III promoter of nonstriated muscle cell differentiation|positive regulation of transcription from Pol III promoter of smooth muscle cell differentiation|upregulation of transcription from RNA polymerase III promoter of nonstriated muscle cell differentiation|up-regulation of transcription from RNA polymerase III promoter of smooth muscle cell differentiation|up regulation of transcription from RNA polymerase III promoter of nonstriated muscle cell differentiation|stimulation of transcription from RNA polymerase III promoter of smooth muscle cell differentiation|positive regulation of transcription from RNA polymerase III promoter of nonstriated muscle cell differentiation|positive regulation of transcription from RNA polymerase III promoter of smooth muscle cell differentiation|activation of transcription from RNA polymerase III promoter of smooth muscle cell differentiation|positive regulation of transcription from RNA polymerase III promoter involved in smooth muscle cell differentiation|up regulation of transcription from RNA polymerase III promoter of smooth muscle cell differentiation OBSOLETE. Any positive regulation of transcription from RNA polymerase III promoter that is involved in smooth muscle cell differentiation. GO:2000746 regulation of defecation rhythm biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000746 regulation of defecation motor program|regulation of DMP|regulation of defecation cycle|regulation of defecation behavior Any process that modulates the frequency, rate or extent of defecation rhythm. GO:1905770 regulation of mesodermal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905770 regulation of mesoderm cell differentiation Any process that modulates the frequency, rate or extent of mesodermal cell differentiation. GO:1905771 negative regulation of mesodermal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905771 down-regulation of mesoderm cell differentiation|negative regulation of mesoderm cell differentiation|downregulation of mesodermal cell differentiation|inhibition of mesoderm cell differentiation|down-regulation of mesodermal cell differentiation|inhibition of mesodermal cell differentiation|down regulation of mesoderm cell differentiation|downregulation of mesoderm cell differentiation|down regulation of mesodermal cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of mesodermal cell differentiation. GO:2000747 negative regulation of defecation rhythm biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000747 negative regulation of defecation behavior|negative regulation of defecation cycle|negative regulation of defecation motor program|negative regulation of DMP Any process that stops, prevents or reduces the frequency, rate or extent of defecation rhythm. GO:1905772 positive regulation of mesodermal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905772 up regulation of mesodermal cell differentiation|activation of mesodermal cell differentiation|up-regulation of mesoderm cell differentiation|upregulation of mesoderm cell differentiation|up-regulation of mesodermal cell differentiation|up regulation of mesoderm cell differentiation|activation of mesoderm cell differentiation|upregulation of mesodermal cell differentiation|positive regulation of mesoderm cell differentiation Any process that activates or increases the frequency, rate or extent of mesodermal cell differentiation. GO:2000748 positive regulation of defecation rhythm biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000748 positive regulation of defecation behavior|positive regulation of defecation cycle|positive regulation of DMP|positive regulation of defecation motor program Any process that activates or increases the frequency, rate or extent of defecation rhythm. GO:2000749 positive regulation of rDNA heterochromatin assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000749 positive regulation of heterochromatic silencing at rDNA|positive regulation of ribosomal DNA heterochromatin assembly|positive regulation of rDNA chromatin silencing|positive regulation of chromatin silencing at ribosomal DNA|positive regulation of chromatin silencing at rDNA Any process that activates or increases the frequency, rate or extent of assembly of rDNA heterochromatin. GO:1905773 8-hydroxy-2'-deoxyguanosine DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1905773 Interacting selectively and non-covalently with 8-hydroxy-2'-deoxyguanosine an oxidized purine residue found in damaged DNA. GO:1905763 MTREC complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1905763 Mtl1-Red1 core complex binding Interacting selectively and non-covalently with a MTREC complex. GO:1905764 regulation of protection from non-homologous end joining at telomere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905764 regulation of protection from NHEJ-mediated telomere fusion Any process that modulates the frequency, rate or extent of protection from non-homologous end joining at telomere. GO:1905765 negative regulation of protection from non-homologous end joining at telomere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905765 inhibition of protection from NHEJ-mediated telomere fusion|down regulation of protection from NHEJ-mediated telomere fusion|downregulation of protection from NHEJ-mediated telomere fusion|down-regulation of protection from non-homologous end joining at telomere|negative regulation of protection from NHEJ-mediated telomere fusion|down-regulation of protection from NHEJ-mediated telomere fusion|downregulation of protection from non-homologous end joining at telomere|down regulation of protection from non-homologous end joining at telomere|inhibition of protection from non-homologous end joining at telomere Any process that stops, prevents or reduces the frequency, rate or extent of protection from non-homologous end joining at telomere. GO:1905766 positive regulation of protection from non-homologous end joining at telomere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905766 upregulation of protection from non-homologous end joining at telomere|up-regulation of protection from NHEJ-mediated telomere fusion|upregulation of protection from NHEJ-mediated telomere fusion|activation of protection from non-homologous end joining at telomere|up-regulation of protection from non-homologous end joining at telomere|up regulation of protection from NHEJ-mediated telomere fusion|activation of protection from NHEJ-mediated telomere fusion|positive regulation of protection from NHEJ-mediated telomere fusion|up regulation of protection from non-homologous end joining at telomere Any process that activates or increases the frequency, rate or extent of protection from non-homologous end joining at telomere. GO:1905767 regulation of double-stranded telomeric DNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905767 Any process that modulates the frequency, rate or extent of double-stranded telomeric DNA binding. CHEBI:16579 anisole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16579 GO:1905768 negative regulation of double-stranded telomeric DNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905768 down regulation of double-stranded telomeric DNA binding|downregulation of double-stranded telomeric DNA binding|down-regulation of double-stranded telomeric DNA binding|inhibition of double-stranded telomeric DNA binding Any process that stops, prevents or reduces the frequency, rate or extent of double-stranded telomeric DNA binding. GO:1905769 positive regulation of double-stranded telomeric DNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905769 upregulation of double-stranded telomeric DNA binding|up regulation of double-stranded telomeric DNA binding|activation of double-stranded telomeric DNA binding|up-regulation of double-stranded telomeric DNA binding Any process that activates or increases the frequency, rate or extent of double-stranded telomeric DNA binding. GO:2000740 negative regulation of mesenchymal stem cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000740 Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell differentiation. CHEBI:16577 3alpha,7alpha-dihydroxy-5beta-cholestan-26-oic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16577 GO:2000741 positive regulation of mesenchymal stem cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000741 Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell differentiation. CHEBI:16578 4-CDP-2-C-methyl-D-erythritol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16578 IAO:0000116 editor note biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/IAO_0000116 GO:0051350 negative regulation of lyase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051350 lyase inhibitor|down-regulation of lyase activity|downregulation of lyase activity|down regulation of lyase activity|inhibition of lyase activity Any process that stops or reduces the rate of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. CHEBI:16576 D-alanyl-D-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16576 CHEBI:16573 carbonyl sulfide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16573 IAO:0000115 definition biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/IAO_0000115 GO:0051353 positive regulation of oxidoreductase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051353 up-regulation of oxidoreductase activity|ribonucleotide reductase activating enzyme activity|upregulation of oxidoreductase activity|oxidoreductase activator|up regulation of oxidoreductase activity|activation of oxidoreductase activity|stimulation of oxidoreductase activity Any process that activates or increases the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. GO:0075320 negative regulation of ascus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075320 Any process that stops, prevents, or reduces the frequency, rate or extent of ascus development, a saclike structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed. CHEBI:16571 oxidised poly(vinyl alcohol) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16571 GO:0051354 negative regulation of oxidoreductase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051354 inhibition of oxidoreductase activity|down regulation of oxidoreductase activity|downregulation of oxidoreductase activity|down-regulation of oxidoreductase activity|oxidoreductase inhibitor Any process that stops or reduces the rate of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. GO:0075321 oomycete sporangium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075321 The process that leads to the development of an oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiates, through specialized cleavage vesicles, into between 10 and 30 zoospores, which are laterally flagellated. CHEBI:16572 3-ethylcatechol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16572 GO:0051351 positive regulation of ligase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051351 up regulation of ligase activity|activation of ligase activity|stimulation of ligase activity|up-regulation of ligase activity|ligase activator|upregulation of ligase activity Any process that activates or increases the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate. GO:0075322 regulation of oomycete sporangium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075322 Any process that modulates the frequency, rate or extent of oomycete sporangium development, a process that leads to the formation of oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiate, through specialized cleavage vesicles, into between 10 and 30 zoospores, which is laterally flagellated. GO:0075323 positive regulation of oomycete sporangium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075323 Any process that activates, maintains or increases the frequency, rate or extent of oomycete sporangium development, a process that leads to the formation of oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiate, through specialized cleavage vesicles, into between 10 and 30 zoospores, which is laterally flagellated. GO:0051352 negative regulation of ligase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051352 down regulation of ligase activity|ligase inhibitor|downregulation of ligase activity|down-regulation of ligase activity|inhibition of ligase activity Any process that stops or reduces the rate of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate. CHEBI:16570 N(6)-hydroxy-L-lysine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16570 GO:0075313 basidium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075313 The process that leads to the development of basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to Basidiomycetes and distinguishes them from other kinds of fungi. GO:0051368 peptidyl-threonine octanoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051368 RESID:AA0386 The octanoylation of peptidyl-threonine to form peptidyl-O3-octanoyl-L-threonine, typical of the protein ghrelin. GO:0051369 peptidyl-threonine decanoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051369 RESID:AA0387 The decanoylation of peptidyl-threonine to form peptidyl-O3-decanoyl-L-threonine, typical of the protein ghrelin. GO:0075314 regulation of basidium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075314 Any process that modulates the frequency, rate or extent of basidium development, a process that leads to the formation of a basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to Basidiomycetes and distinguishes them from other kinds of fungi. GO:0075315 positive regulation of basidium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075315 Any process that activates, maintains or increases the frequency, rate or extent of basidium development, a process that leads to the formation of basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to basidiomycetes and distinguishes them from other kinds of fungi. GO:0051366 protein decanoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051366 protein amino acid decanoylation The modification of a protein amino acid by formation of an ester or amide with decanoic acid. GO:0051367 peptidyl-serine decanoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051367 RESID:AA0385 The decanoylation of peptidyl-serine to form peptidyl-O3-decanoyl-L-serine, typical of the protein ghrelin. GO:0075316 negative regulation of basidium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075316 Any process that stops, prevents, or reduces the frequency, rate or extent of basidium development, a process that leads to the formation of basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to basidiomycetes and distinguishes them from other kinds of fungi. GO:0075317 ascus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075317 The process that leads to the development of ascus, a sac-like structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed. GO:0075318 regulation of ascus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075318 Any process that modulates the frequency, rate or extent of ascus development, a process that leads to the formation of basidium, a sac-like structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed. GO:0075319 positive regulation of ascus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075319 Any process that activates, maintains or increases the frequency, rate or extent of ascus development, a saclike structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed. GO:2000753 positive regulation of glucosylceramide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000753 positive regulation of glucosylceramide catabolism|positive regulation of glucosylceramide degradation|positive regulation of glucosylceramide breakdown Any process that activates or increases the frequency, rate or extent of glucosylceramide catabolic process. GO:2000754 regulation of sphingomyelin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000754 regulation of sphingomyelin degradation|regulation of sphingomyelin breakdown|regulation of sphingomyelin catabolism Any process that modulates the frequency, rate or extent of sphingomyelin catabolic process. GO:2000755 positive regulation of sphingomyelin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000755 positive regulation of sphingomyelin degradation|positive regulation of sphingomyelin catabolism|positive regulation of sphingomyelin breakdown Any process that activates or increases the frequency, rate or extent of sphingomyelin catabolic process. GO:2000756 regulation of peptidyl-lysine acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000756 Any process that modulates the frequency, rate or extent of peptidyl-lysine acetylation. GO:1905780 regulation of phosphatidylserine exposure on apoptotic cell surface biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905780 regulation of externalization of phosphatidylserine Any process that modulates the frequency, rate or extent of phosphatidylserine exposure on apoptotic cell surface. GO:1905781 negative regulation of phosphatidylserine exposure on apoptotic cell surface biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905781 down regulation of externalization of phosphatidylserine|downregulation of externalization of phosphatidylserine|down-regulation of phosphatidylserine exposure on apoptotic cell surface|inhibition of phosphatidylserine exposure on apoptotic cell surface|negative regulation of externalization of phosphatidylserine|down-regulation of externalization of phosphatidylserine|inhibition of externalization of phosphatidylserine|down regulation of phosphatidylserine exposure on apoptotic cell surface|downregulation of phosphatidylserine exposure on apoptotic cell surface Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylserine exposure on apoptotic cell surface. GO:2000757 negative regulation of peptidyl-lysine acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000757 Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-lysine acetylation. GO:1905782 positive regulation of phosphatidylserine exposure on apoptotic cell surface biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905782 upregulation of externalization of phosphatidylserine|up regulation of phosphatidylserine exposure on apoptotic cell surface|activation of phosphatidylserine exposure on apoptotic cell surface|up regulation of externalization of phosphatidylserine|positive regulation of externalization of phosphatidylserine|activation of externalization of phosphatidylserine|up-regulation of phosphatidylserine exposure on apoptotic cell surface|up-regulation of externalization of phosphatidylserine|upregulation of phosphatidylserine exposure on apoptotic cell surface Any process that activates or increases the frequency, rate or extent of phosphatidylserine exposure on apoptotic cell surface. GO:2000758 positive regulation of peptidyl-lysine acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000758 Any process that activates or increases the frequency, rate or extent of peptidyl-lysine acetylation. GO:1905783 CENP-A containing nucleosome disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905783 centromere specific nucleosome disassembly|centromere-specific nucleosome disassembly|centromeric nucleosome disassembly The disaggregation of a CENP-A containing nucleosome into its constituent components. GO:2000759 regulation of N-terminal peptidyl-lysine acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000759 Any process that modulates the frequency, rate or extent of N-terminal peptidyl-lysine acetylation. GO:1905784 regulation of anaphase-promoting complex-dependent catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905784 Any process that modulates the frequency, rate or extent of anaphase-promoting complex-dependent catabolic process. GO:1905774 regulation of DNA helicase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905774 regulation of ATP-dependent DNA helicase activity Any process that modulates the frequency, rate or extent of ATP-dependent DNA helicase activity. GO:1905775 negative regulation of DNA helicase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905775 negative regulation of ATP-dependent DNA helicase activity|down regulation of ATP-dependent DNA helicase activity|inhibition of DNA helicase activity|downregulation of ATP-dependent DNA helicase activity|down-regulation of ATP-dependent DNA helicase activity|down regulation of DNA helicase activity|downregulation of DNA helicase activity|inhibition of ATP-dependent DNA helicase activity|down-regulation of DNA helicase activity Any process that stops, prevents or reduces the frequency, rate or extent of ATP-dependent DNA helicase activity. IAO:0000120 metadata complete biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/IAO_0000120 Class has all its metadata, but is either not guaranteed to be in its final location in the asserted IS_A hierarchy or refers to another class that is not complete. GO:1905776 positive regulation of DNA helicase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905776 upregulation of ATP-dependent DNA helicase activity|up-regulation of DNA helicase activity|up regulation of ATP-dependent DNA helicase activity|activation of ATP-dependent DNA helicase activity|upregulation of DNA helicase activity|up-regulation of ATP-dependent DNA helicase activity|up regulation of DNA helicase activity|activation of DNA helicase activity|positive regulation of ATP-dependent DNA helicase activity Any process that activates or increases the frequency, rate or extent of ATP-dependent DNA helicase activity. GO:1905777 regulation of exonuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905777 regulation of exonuclease IX activity Any process that modulates the frequency, rate or extent of exonuclease activity. GO:1905778 negative regulation of exonuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905778 inhibition of exonuclease IX activity|down-regulation of exonuclease activity|down regulation of exonuclease IX activity|downregulation of exonuclease IX activity|downregulation of exonuclease activity|down regulation of exonuclease activity|inhibition of exonuclease activity|negative regulation of exonuclease IX activity|down-regulation of exonuclease IX activity Any process that stops, prevents or reduces the frequency, rate or extent of exonuclease activity. CHEBI:16568 5,10-methylenetetrahydromethanopterin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16568 GO:2000750 negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000750 Any process that stops, prevents or reduces the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape. GO:1905779 positive regulation of exonuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905779 up-regulation of exonuclease IX activity|up-regulation of exonuclease activity|activation of exonuclease activity|upregulation of exonuclease IX activity|up regulation of exonuclease activity|up regulation of exonuclease IX activity|positive regulation of exonuclease IX activity|upregulation of exonuclease activity|activation of exonuclease IX activity Any process that activates or increases the frequency, rate or extent of exonuclease activity. CHEBI:16569 3-hydroxyquinolin-4(1H)-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16569 GO:2000751 histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000751 histone H3-T3 phosphorylation of CPC localization to kinetochore|histone H3-T3 phosphorylation of chromosome passenger complex localization to kinetochore|histone H3-T3 phosphorylation of chromosome passenger complex localisation to kinetochore|histone H3-T3 phosphorylation of CPC complex localization to kinetochore|histone H3-T3 phosphorylation of chromosomal passenger complex localization to kinetochore Any histone H3-T3 phosphorylation that is involved in chromosome passenger complex localization to kinetochore. CHEBI:16566 sphinganine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16566 GO:2000752 regulation of glucosylceramide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000752 regulation of glucosylceramide breakdown|regulation of glucosylceramide catabolism|regulation of glucosylceramide degradation Any process that modulates the frequency, rate or extent of glucosylceramide catabolic process. CHEBI:16567 anthranilate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16567 GO:0051360 peptide cross-linking via L-asparagine 5-imidazolinone glycine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051360 RESID:AA0380 biosynthetic process of protein-protein cross-link via L-asparagine 5-imidazolinone glycine|biosynthesis of protein-protein cross-link via L-asparagine 5-imidazolinone glycine The formation of the fluorescent protein FP506 chromophore cross-link from the alpha-carboxyl carbon of residue n, an asparagine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons. GO:0051361 peptide cross-linking via L-lysine 5-imidazolinone glycine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051361 RESID:AA0381 biosynthetic process of protein-protein cross-link via L-lysine 5-imidazolinone glycine|biosynthesis of protein-protein cross-link via L-lysine 5-imidazolinone glycine The formation of a fluorescent protein chromophore cross-link from the alpha-carboxyl carbon of residue n, a lysine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons. IAO:0000125 pending final vetting biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/IAO_0000125 All definitions, placement in the asserted IS_A hierarchy and required minimal metadata are complete. The class is awaiting a final review by someone other than the term editor. CHEBI:16562 2-phenylacetamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16562 CHEBI:16563 tetrahydropalmatine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16563 IAO:0000123 metadata incomplete biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/IAO_0000123 Class is being worked on; however, the metadata (including definition) are not complete or sufficiently clear to the branch editors. GO:0051364 N-terminal peptidyl-proline N-formylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051364 RESID:AA0384 The formylation of the N-terminal proline of proteins to form the derivative N-formylproline. GO:0051365 cellular response to potassium ion starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051365 cellular response to potassium ion deprivation|cellular response to potassium starvation|cellular response to K+ ion starvation|cellular response to K+ ion deprivation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of potassium ions. IAO:0000124 uncurated biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/IAO_0000124 Nothing done yet beyond assigning a unique class ID and proposing a preferred term. GO:0075310 regulation of sporangium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075310 Any process that modulates the frequency, rate or extent of sporangium development, a process that leads to the formation of sporangium, a single-celled or many-celled structure in which spores are produced, as in fungi, algae, mosses, and ferns, gymnosperms, angiosperms. GO:0075311 positive regulation of sporangium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075311 Any process that activates, maintains or increases the frequency, rate or extent of sporangium development, a process that leads to the formation of sporangium, a single-celled or many-celled structure in which spores are produced, as in fungi, algae, mosses, and ferns, gymnosperms, angiosperms. GO:0051362 peptide cross-linking via 2-tetrahydropyridinyl-5-imidazolinone glycine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051362 RESID:AA0382 biosynthetic process of protein-protein cross-link via 2-tetrahydropyridinyl-5-imidazolinone glycine|biosynthesis of protein-protein cross-link via 2-tetrahydropyridinyl-5-imidazolinone glycine The formation of a 2-tetrahydropyridinyl-5-imidazolinone protein chromophore cross-link from the alpha-carboxyl carbon of residue n, a lysine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons. In addition, the residue N lysine undergoes cyclization. The alpha-amino nitrogen is replaced by the epsilon-amino nitrogen, the peptide chain is broken, residue N-1 is released as an amide, and a double bond is formed between the alpha-carbon and the nitrogen so that a tetrahydropyridine ring results. This modification is found in the GFP-like fluorescent chromoprotein FP538 from the sea anemone Zoanthus species. IAO:0000121 organizational term biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/IAO_0000121 term created to ease viewing/sort terms for development purpose, and will not be included in a release IAO:0000122 ready for release biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/IAO_0000122 Class has undergone final review, is ready for use, and will be included in the next release. Any class lacking "ready_for_release" should be considered likely to change place in hierarchy, have its definition refined, or be obsoleted in the next release. Those classes deemed "ready_for_release" will also derived from a chain of ancestor classes that are also "ready_for_release." GO:0051363 peptidoglycan-protein cross-linking via L-alanyl-pentaglycyl-murein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051363 RESID:AA0383 The process of linking a protein to peptidoglycan via a carboxy terminal alanine carboxyl group through a pentaglycyl peptide to the lysine or diaminopimelic acid of the peptidoglycan. GO:0075312 negative regulation of sporangium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075312 Any process that stops, prevents, or reduces the frequency, rate or extent of sporangium development, a process that leads to the formation of sporangium, a single-celled or many-celled structure in which spores are produced, as in fungi, algae, mosses, and ferns, gymnosperms, angiosperms. GO:0075346 modification by symbiont of host protein by ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075346 modification by symbiont of host protein by ubiquitylation|modification by symbiont of host protein by ubiquitinylation The process in which an organism adds one or more ubiquitin groups to a protein of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051379 epinephrine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051379 adrenaline binding Interacting selectively and non-covalently with epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine. GO:0051377 mannose-ethanolamine phosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051377 Reactome:R-HSA-162798 phosphoethanolamine transferase activity|ethanolamine phosphate transferase activity|EtN-P transferase activity|addition of ethanolamine phosphate to mannose of GPI precursor Catalysis of the transfer of ethanolamine phosphate to a mannose residue in the GPI lipid precursor. GO:0051378 serotonin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051378 5-hydroxytryptamine binding Interacting selectively and non-covalently with serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. GO:2000764 positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000764 positive regulation of semaphorin-plexin signalling pathway involved in outflow tract morphogenesis Any process that activates or increases the frequency, rate or extent of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis. GO:2000765 regulation of cytoplasmic translation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000765 Any process that modulates the frequency, rate or extent of cytoplasmic translation. GO:2000766 negative regulation of cytoplasmic translation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000766 Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translation. GO:1905790 regulation of mechanosensory behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905790 regulation of behavioral response to mechanical stimulus|regulation of mechanosensory behaviour|regulation of behavioural response to mechanical stimulus Any process that modulates the frequency, rate or extent of mechanosensory behavior. GO:1905791 negative regulation of mechanosensory behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905791 downregulation of behavioral response to mechanical stimulus|down-regulation of mechanosensory behaviour|negative regulation of mechanosensory behaviour|inhibition of mechanosensory behavior|down regulation of behavioral response to mechanical stimulus|inhibition of behavioral response to mechanical stimulus|down-regulation of behavioural response to mechanical stimulus|negative regulation of behavioural response to mechanical stimulus|downregulation of mechanosensory behaviour|inhibition of behavioural response to mechanical stimulus|down regulation of mechanosensory behaviour|inhibition of mechanosensory behaviour|down regulation of mechanosensory behavior|downregulation of mechanosensory behavior|negative regulation of behavioral response to mechanical stimulus|down-regulation of behavioral response to mechanical stimulus|down regulation of behavioural response to mechanical stimulus|down-regulation of mechanosensory behavior|downregulation of behavioural response to mechanical stimulus Any process that stops, prevents or reduces the frequency, rate or extent of mechanosensory behavior. GO:2000767 positive regulation of cytoplasmic translation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000767 Any process that activates or increases the frequency, rate or extent of cytoplasmic translation. GO:1905792 positive regulation of mechanosensory behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905792 up regulation of behavioural response to mechanical stimulus|activation of behavioural response to mechanical stimulus|up-regulation of mechanosensory behavior|positive regulation of behavioural response to mechanical stimulus|positive regulation of mechanosensory behaviour|upregulation of behavioral response to mechanical stimulus|up regulation of mechanosensory behaviour|upregulation of mechanosensory behavior|up-regulation of behavioural response to mechanical stimulus|up-regulation of behavioral response to mechanical stimulus|activation of behavioral response to mechanical stimulus|upregulation of mechanosensory behaviour|up regulation of mechanosensory behavior|upregulation of behavioural response to mechanical stimulus|activation of mechanosensory behavior|up-regulation of mechanosensory behaviour|positive regulation of behavioral response to mechanical stimulus|activation of mechanosensory behaviour|up regulation of behavioral response to mechanical stimulus Any process that activates or increases the frequency, rate or extent of mechanosensory behavior. GO:2000768 positive regulation of nephron tubule epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000768 Any process that activates or increases the frequency, rate or extent of nephron tubule epithelial cell differentiation. GO:1905793 protein localization to pericentriolar material biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905793 protein localisation in pericentriolar material|protein localisation to pericentriolar material|protein localization in pericentriolar material A process in which a protein is transported to, or maintained in, a location within a pericentriolar material. GO:2000769 regulation of establishment or maintenance of cell polarity regulating cell shape biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000769 Any process that modulates the frequency, rate or extent of establishment or maintenance of cell polarity regulating cell shape. GO:1905794 response to puromycin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905794 response to 3'-deoxy-N,N-dimethyl-3'-(O-methyl-L-tyrosinamido)adenosine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a puromycin stimulus. GO:1905795 cellular response to puromycin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905795 cellular response to 3'-deoxy-N,N-dimethyl-3'-(O-methyl-L-tyrosinamido)adenosine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a puromycin stimulus. GO:1905785 negative regulation of anaphase-promoting complex-dependent catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905785 Any process that stops, prevents or reduces the frequency, rate or extent of anaphase-promoting complex-dependent catabolic process. GO:1905786 positive regulation of anaphase-promoting complex-dependent catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905786 Any process that activates or increases the frequency, rate or extent of anaphase-promoting complex-dependent catabolic process. GO:1905787 regulation of detection of mechanical stimulus involved in sensory perception of touch biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905787 regulation of sensory transduction of mechanical stimulus during perception of touch|regulation of sensory detection of mechanical stimulus during perception of touch|regulation of tactition, sensory detection of mechanical stimulus|regulation of perception of touch, sensory transduction of mechanical stimulus|regulation of perception of touch, sensory detection of mechanical stimulus|regulation of perception of touch, detection of mechanical stimulus Any process that modulates the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch. GO:1905788 negative regulation of detection of mechanical stimulus involved in sensory perception of touch biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905788 down-regulation of detection of mechanical stimulus involved in sensory perception of touch|negative regulation of perception of touch, sensory detection of mechanical stimulus|down-regulation of perception of touch, sensory detection of mechanical stimulus|downregulation of sensory transduction of mechanical stimulus during perception of touch|negative regulation of perception of touch, detection of mechanical stimulus|down-regulation of perception of touch, detection of mechanical stimulus|down regulation of sensory detection of mechanical stimulus during perception of touch|down regulation of tactition, sensory detection of mechanical stimulus|down regulation of sensory transduction of mechanical stimulus during perception of touch|downregulation of detection of mechanical stimulus involved in sensory perception of touch|inhibition of sensory transduction of mechanical stimulus during perception of touch|downregulation of sensory detection of mechanical stimulus during perception of touch|inhibition of perception of touch, sensory detection of mechanical stimulus|inhibition of perception of touch, detection of mechanical stimulus|downregulation of tactition, sensory detection of mechanical stimulus|down regulation of detection of mechanical stimulus involved in sensory perception of touch|down-regulation of perception of touch, sensory transduction of mechanical stimulus|negative regulation of perception of touch, sensory transduction of mechanical stimulus|inhibition of detection of mechanical stimulus involved in sensory perception of touch|negative regulation of sensory detection of mechanical stimulus during perception of touch|down-regulation of sensory detection of mechanical stimulus during perception of touch|downregulation of perception of touch, sensory transduction of mechanical stimulus|down-regulation of tactition, sensory detection of mechanical stimulus|negative regulation of tactition, sensory detection of mechanical stimulus|down regulation of perception of touch, sensory detection of mechanical stimulus|down regulation of perception of touch, detection of mechanical stimulus|inhibition of sensory detection of mechanical stimulus during perception of touch|down regulation of perception of touch, sensory transduction of mechanical stimulus|inhibition of perception of touch, sensory transduction of mechanical stimulus|downregulation of perception of touch, sensory detection of mechanical stimulus|down-regulation of sensory transduction of mechanical stimulus during perception of touch|inhibition of tactition, sensory detection of mechanical stimulus|negative regulation of sensory transduction of mechanical stimulus during perception of touch|downregulation of perception of touch, detection of mechanical stimulus Any process that stops, prevents or reduces the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch. GO:1905789 positive regulation of detection of mechanical stimulus involved in sensory perception of touch biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905789 upregulation of perception of touch, sensory transduction of mechanical stimulus|up-regulation of tactition, sensory detection of mechanical stimulus|up regulation of perception of touch, sensory detection of mechanical stimulus|up regulation of perception of touch, detection of mechanical stimulus|activation of perception of touch, sensory detection of mechanical stimulus|positive regulation of sensory transduction of mechanical stimulus during perception of touch|positive regulation of perception of touch, sensory detection of mechanical stimulus|positive regulation of perception of touch, detection of mechanical stimulus|activation of perception of touch, detection of mechanical stimulus|up regulation of sensory transduction of mechanical stimulus during perception of touch|upregulation of sensory detection of mechanical stimulus during perception of touch|up regulation of detection of mechanical stimulus involved in sensory perception of touch|upregulation of tactition, sensory detection of mechanical stimulus|up-regulation of perception of touch, sensory transduction of mechanical stimulus|activation of perception of touch, sensory transduction of mechanical stimulus|up-regulation of perception of touch, sensory detection of mechanical stimulus|upregulation of sensory transduction of mechanical stimulus during perception of touch|up-regulation of perception of touch, detection of mechanical stimulus|up regulation of sensory detection of mechanical stimulus during perception of touch|activation of sensory detection of mechanical stimulus during perception of touch|positive regulation of sensory detection of mechanical stimulus during perception of touch|upregulation of detection of mechanical stimulus involved in sensory perception of touch|up regulation of tactition, sensory detection of mechanical stimulus|positive regulation of perception of touch, sensory transduction of mechanical stimulus|activation of tactition, sensory detection of mechanical stimulus|positive regulation of tactition, sensory detection of mechanical stimulus|up regulation of perception of touch, sensory transduction of mechanical stimulus|upregulation of perception of touch, sensory detection of mechanical stimulus|upregulation of perception of touch, detection of mechanical stimulus|up-regulation of sensory transduction of mechanical stimulus during perception of touch|activation of sensory transduction of mechanical stimulus during perception of touch|up-regulation of detection of mechanical stimulus involved in sensory perception of touch|activation of detection of mechanical stimulus involved in sensory perception of touch|up-regulation of sensory detection of mechanical stimulus during perception of touch Any process that activates or increases the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch. GO:2000760 negative regulation of N-terminal peptidyl-lysine acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000760 Any process that stops, prevents or reduces the frequency, rate or extent of N-terminal peptidyl-lysine acetylation. GO:2000761 positive regulation of N-terminal peptidyl-lysine acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000761 Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-lysine acetylation. GO:2000762 regulation of phenylpropanoid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000762 regulation of phenylpropanoid metabolism Any process that modulates the frequency, rate or extent of phenylpropanoid metabolic process. CHEBI:16599 1,2-diacyl-3-[3-(alpha-D-N-acetylneuraminyl)-beta-D-galactosyl]-sn-glycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16599 GO:2000763 positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000763 positive regulation of transcription from Pol II promoter involved in norepinephrine anabolism|positive regulation of transcription from Pol II promoter involved in norepinephrine biosynthetic process|positive regulation of transcription from Pol II promoter involved in norepinephrine biosynthesis|positive regulation of transcription from Pol II promoter involved in noradrenaline biosynthesis|positive regulation of transcription from Pol II promoter involved in norepinephrine synthesis|positive regulation of transcription from Pol II promoter involved in noradrenaline biosynthetic process|positive regulation of transcription from Pol II promoter involved in norepinephrine formation|positive regulation of transcription from Pol II promoter involved in levarterenol biosynthesis|positive regulation of transcription from Pol II promoter involved in levarterenol biosynthetic process Any positive regulation of transcription from RNA polymerase II promoter that is involved in norepinephrine biosynthetic process. GO:0051371 muscle alpha-actinin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051371 alpha-actinin 3 binding|alpha-actinin 2 binding Interacting selectively and non-covalently with muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc. CHEBI:16597 glycerol 1,2-cyclic phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16597 CHEBI:16598 DDE biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16598 GO:0051372 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051372 GO:0075340 obsolete negative regulation of growth or development of symbiont during interaction with host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075340 negative regulation of growth or development of symbiont during interaction with host OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism. CHEBI:16595 1D-myo-inositol 1,4,5-trisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16595 GO:0075341 host cell PML body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0075341 host cell PML nuclear body|host cell PML NB A nuclear body that reacts against SP100 auto-antibodies (PML = promyelocytic leukemia) located within a cell of a host organism. GO:0051370 obsolete ZASP binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051370 ZASP binding|Z-band alternatively spliced PDZ-motif protein binding OBSOLETE. Interacting selectively and non-covalently with Z-band alternatively spliced PDZ motif protein (ZASP). ZASP is a Z-band protein specifically expressed in heart and skeletal muscle. This protein contains N-terminal PDZ domain and C-terminal LIM domain. CHEBI:16596 cyanidin 3-O-rutinoside 5-O-beta-D-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16596 GO:0075342 disruption by symbiont of host cell PML body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075342 catabolism by symbiont of host cell PML body|disassembly by symbiont of host cell PML nuclear body|disassembly by symbiont of host cell PML body during symbiotic interaction|disassembly by symbiont of host cell PML NB|degradation by symbiont of host cell PML body|disassembly by symbiont of host cell PML body The breakdown, by the symbiont, of a PML body within a host cell. A PML body is a nuclear body that reacts against SP100 auto-antibodies (PML = promyelocytic leukemia). The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:16593 L-xylulose 5-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16593 GO:0051375 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051375 GO:0075343 modulation by symbiont of abscisic acid levels in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075343 The alteration by an organism of the levels of abscisic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051376 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051376 CHEBI:16594 2,4-diaminopentanoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16594 GO:0051373 FATZ binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051373 filamin-, actinin- and telethonin-binding protein of the Z-disc of striated muscle|calsarcin 3 binding|calsarcin 2 binding|calsarcin 1 binding|FATZ 3 binding|FATZ 2 binding|FATZ 1 binding|calsarcin binding Interacting selectively and non-covalently with a member of the FATZ family of proteins, filamin-, actinin-, and telethonin-binding proteins of the Z-disc of striated muscle. FATZ proteins are located in the Z-disc of the sarcomere and are involved in a complex network of interactions with other Z-band components. GO:0075344 obsolete modulation by symbiont of host protein levels biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075344 OBSOLETE. The alteration by an organism of protein levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:16591 all-trans-undecaprenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16591 GO:0075345 modification by symbiont of host protein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075345 The covalent alteration by an organism of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:16592 (S)-canadine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16592 GO:0051374 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051374 GO:0075335 obsolete positive regulation of symbiont adenylate cyclase-mediated signal transduction in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075335 OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its adenylate cyclase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0075336 obsolete negative regulation of symbiont adenylate cyclase-mediated signal transduction in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075336 OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont adenylate cyclase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:16590 O-feruloylgalactaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16590 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051388 positive regulation of nerve growth factor receptor signalling pathway|positive regulation of NGF receptor signalling pathway|positive regulation of nerve growth factor receptor signaling pathway|upregulation of nerve growth factor receptor signaling pathway|stimulation of nerve growth factor receptor signaling pathway|activation of nerve growth factor receptor signaling pathway|up-regulation of nerve growth factor receptor signaling pathway|positive regulation of NGF receptor signaling pathway|up regulation of nerve growth factor receptor signaling pathway Any process that activates or increases the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway. GO:0075337 obsolete positive regulation of growth or development of symbiont on or near host surface biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075337 positive regulation of growth or development of symbiont on or near host surface OBSOLETE. Any process that activates or increases the frequency, rate or extent of the symbiont's increase in size or mass, or its progression from an initial condition to a later condition, on or near the cells or tissues of the host organism. GO:0075338 obsolete modulation of growth or development of symbiont during interaction with host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075338 modulation of growth or development of symbiont during interaction with host OBSOLETE. Any process that modulates the frequency, rate or extent of the increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism. GO:0051389 inactivation of MAPKK activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051389 termination of MAPKK activity|termination of MAP kinase kinase activity|inactivation of MAP kinase kinase activity Any process that terminates the activity of the active enzyme MAP kinase kinase (MAPKK). GO:0075339 obsolete positive regulation of growth or development of symbiont during interaction with host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075339 positive regulation of growth or development of symbiont during interaction with host OBSOLETE. Any process that activates or increases the frequency, rate or extent of the increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism. GO:2000775 histone H3-S10 phosphorylation involved in chromosome condensation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000775 histone H3 phosphorylation at S10 of chromosome condensation|histone H3S10 phosphorylation of chromosome condensation|histone H3-S10 phosphorylation of chromosome condensation Any histone H3-S10 phosphorylation that is involved in chromosome condensation. GO:2000776 histone H4 acetylation involved in response to DNA damage stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000776 histone H4 acetylation of cellular response to DNA damage stimulus|histone H4 acetylation of DNA damage response|histone H4 acetylation of response to genotoxic stress|histone H4 acetylation of response to DNA damage stimulus|histone H4 acetylation of cellular DNA damage response Any histone H4 acetylation that is involved in a response to DNA damage stimulus. GO:2000777 positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000777 positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to lowered oxygen tension|positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxic stress Any positive regulation of proteasomal ubiquitin-dependent protein catabolic process that is involved in a cellular response to hypoxia. GO:2000778 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2000778 GO:2000779 regulation of double-strand break repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000779 Any process that modulates the frequency, rate or extent of double-strand break repair. GO:1905796 regulation of intraciliary anterograde transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905796 regulation of intraflagellar anterograde transport Any process that modulates the frequency, rate or extent of intraciliary anterograde transport. GO:1905797 negative regulation of intraciliary anterograde transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905797 down-regulation of intraflagellar anterograde transport|negative regulation of intraflagellar anterograde transport|down-regulation of intraciliary anterograde transport|downregulation of intraflagellar anterograde transport|down regulation of intraflagellar anterograde transport|downregulation of intraciliary anterograde transport|inhibition of intraflagellar anterograde transport|down regulation of intraciliary anterograde transport|inhibition of intraciliary anterograde transport Any process that stops, prevents or reduces the frequency, rate or extent of intraciliary anterograde transport. GO:1905798 positive regulation of intraciliary anterograde transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905798 upregulation of intraciliary anterograde transport|activation of intraflagellar anterograde transport|up-regulation of intraflagellar anterograde transport|activation of intraciliary anterograde transport|up-regulation of intraciliary anterograde transport|positive regulation of intraflagellar anterograde transport|up regulation of intraflagellar anterograde transport|up regulation of intraciliary anterograde transport|upregulation of intraflagellar anterograde transport Any process that activates or increases the frequency, rate or extent of intraciliary anterograde transport. GO:1905799 regulation of intraciliary retrograde transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905799 regulation of intraflagellar retrograde transport Any process that modulates the frequency, rate or extent of intraciliary retrograde transport. GO:2000770 negative regulation of establishment or maintenance of cell polarity regulating cell shape biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000770 Any process that stops, prevents or reduces the frequency, rate or extent of establishment or maintenance of cell polarity regulating cell shape. GO:2000771 positive regulation of establishment or maintenance of cell polarity regulating cell shape biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000771 Any process that activates or increases the frequency, rate or extent of establishment or maintenance of cell polarity regulating cell shape. GO:2000772 regulation of cellular senescence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000772 Any process that modulates the frequency, rate or extent of cellular senescence. GO:2000773 negative regulation of cellular senescence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000773 Any process that stops, prevents or reduces the frequency, rate or extent of cellular senescence. CHEBI:16588 D-hamamelose 2(1)-(dihydrogen phosphate) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16588 GO:2000774 positive regulation of cellular senescence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000774 Any process that activates or increases the frequency, rate or extent of cellular senescence. GO:0051382 kinetochore assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051382 centromere/kinetochore complex maturation|kinetochore formation|centromere and kinetochore complex maturation|chromosome-kinetochore attachment The aggregation, arrangement and bonding together of a set of components to form the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules. CHEBI:16586 6-aminohexanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16586 CHEBI:16587 20-hydroxyecdysone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16587 GO:0051383 kinetochore organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051383 kinetochore organization and biogenesis|kinetochore organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules. GO:0051380 norepinephrine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051380 noradrenaline binding Interacting selectively and non-covalently with norepinephrine, (3,4-dihydroxyphenyl-2-aminoethanol), a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine. CHEBI:16584 isopentenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16584 GO:0075330 positive regulation of arbuscule formation for nutrient acquisition from host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075330 Any process that activates or increases the frequency, rate or extent of symbiont arbuscule formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051381 histamine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051381 Interacting selectively and non-covalently with histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. CHEBI:16585 L-lombricine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16585 GO:0075331 negative regulation of arbuscule formation for nutrient acquisition from host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075331 Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont arbuscule formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:16582 oxaluric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16582 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051386 regulation of nerve growth factor receptor signaling pathway|regulation of nerve growth factor receptor signalling pathway|regulation of NGF receptor signaling pathway|regulation of NGF receptor signalling pathway Any process that modulates the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway. CHEBI:16583 butane-2,3-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16583 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051387 downregulation of nerve growth factor receptor signaling pathway|negative regulation of nerve growth factor receptor signaling pathway|negative regulation of nerve growth factor receptor signalling pathway|down regulation of nerve growth factor receptor signaling pathway|inhibition of nerve growth factor receptor signaling pathway|negative regulation of NGF receptor signalling pathway|negative regulation of NGF receptor signaling pathway|down-regulation of nerve growth factor receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway. GO:0075332 obsolete modulation by host of symbiont adenylate cyclase-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075332 OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051384 response to glucocorticoid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051384 response to glucocorticoid stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects. GO:0075333 obsolete positive regulation by host of symbiont adenylate cyclase-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075333 OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:16581 pregnenolone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16581 GO:0075334 obsolete modulation of symbiont adenylate cyclase-mediated signal transduction in response to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075334 OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its adenylate cyclase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0051385 response to mineralocorticoid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051385 response to mineralocorticoid stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance. GO:2000706 negative regulation of dense core granule biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000706 Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule biogenesis. GO:2000707 positive regulation of dense core granule biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000707 Any process that activates or increases the frequency, rate or extent of dense core granule biogenesis. GO:2000708 myosin filament organization involved in cytokinetic actomyosin contractile ring assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000708 myosin filament organization of contractile ring assembly|myosin filament assembly or disassembly of cytokinesis, actomyosin contractile ring formation|myosin filament organization of cytokinesis, actomyosin contractile ring formation|myosin filament assembly or disassembly of constriction ring assembly|myosin filament organization of constriction ring assembly|myosin filament organization of cytokinesis, actomyosin contractile ring assembly|myosin filament assembly or disassembly of contractile ring assembly|myosin polymerization or depolymerization of contractile ring assembly|myosin filament assembly or disassembly of cytokinesis, actomyosin contractile ring assembly|myosin polymerization or depolymerization of cytokinesis, actomyosin contractile ring assembly|myosin polymerization or depolymerization of cytokinesis, actomyosin ring formation|myosin filament organization of cytokinesis, actomyosin ring formation|myosin filament assembly or disassembly of cytokinesis, actomyosin ring formation|myosin filament organization of cytokinesis, actomyosin ring biosynthesis|myosin filament assembly or disassembly of cytokinesis, actomyosin ring biosynthesis|myosin polymerization or depolymerization of cytokinesis, actomyosin ring biosynthesis|myosin polymerization or depolymerization of cytokinesis, contractile ring assembly|myosin filament organisation involved in cytokinetic actomyosin contractile ring assembly|myosin filament organization of cytokinesis, contractile ring assembly|myosin filament assembly or disassembly of cytokinesis, contractile ring assembly|myosin polymerization or depolymerization of cytokinesis, actomyosin contractile ring formation|myosin polymerization or depolymerization of constriction ring assembly A myosin filament organization process that contributes to actomyosin contractile ring assembly during cytokinesis. GO:0051399 obsolete N-terminal arginine aminopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051399 arginine aminopeptidase activity|N-terminal arginine aminopeptidase activity|argininyl aminopeptidase activity OBSOLETE. Catalysis of the hydrolysis of an arginine residue from the N-terminal of an oligopeptide or polypeptide chain. GO:2000709 regulation of maintenance of meiotic sister chromatid cohesion, centromeric biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000709 regulation of maintenance of meiotic sister chromatin cohesion at centromere|regulation of maintenance of sister chromatin cohesion at centromere at meiosis I|regulation of maintenance of centromeric meiotic sister chromatin cohesion Any process that modulates the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion in the centromeric region. GO:2000700 positive regulation of cardiac muscle cell myoblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000700 positive regulation of cardiac myoblast differentiation|positive regulation of myocardial precursor cell differentiation Any process that activates or increases the frequency, rate or extent of cardiac muscle cell myoblast differentiation. GO:2000701 glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000701 glial cell derived neurotrophic factor receptor signaling pathway of ureteric bud formation|glial cell line-derived neurotrophic factor receptor signalling pathway of ureteric bud formation|glial cell-derived neurotrophic factor receptor signaling pathway of ureteric bud formation|glial cell-derived neurotrophic factor receptor signalling pathway of ureteric bud formation|GDNF receptor signaling pathway of ureteric bud formation The series of molecular signals generated as a consequence of a glial cell-derived neurotrophic factor receptor binding to one of its physiological ligands that contributes to the formation of the ureteric bud from the Wolffian duct. GO:2000702 regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000702 regulation of fibroblast growth factor receptor signaling pathway of ureteric bud formation|regulation of FGFR signaling pathway of ureteric bud formation|regulation of fibroblast growth factor receptor signalling pathway of ureteric bud formation|regulation of FGF receptor signalling pathway of ureteric bud formation|regulation of FGF receptor signaling pathway of ureteric bud formation Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation. GO:2000703 negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000703 negative regulation of fibroblast growth factor receptor signaling pathway of ureteric bud formation|negative regulation of FGF receptor signaling pathway of ureteric bud formation|negative regulation of FGF receptor signalling pathway of ureteric bud formation|negative regulation of FGFR signaling pathway of ureteric bud formation|negative regulation of fibroblast growth factor receptor signalling pathway of ureteric bud formation Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation. GO:2000704 positive regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000704 positive regulation of FGFR signaling pathway of ureteric bud formation|positive regulation of fibroblast growth factor receptor signalling pathway of ureteric bud formation|positive regulation of fibroblast growth factor receptor signaling pathway of ureteric bud formation|positive regulation of FGF receptor signalling pathway of ureteric bud formation|positive regulation of FGF receptor signaling pathway of ureteric bud formation Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation. GO:2000705 regulation of dense core granule biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000705 Any process that modulates the frequency, rate or extent of dense core granule biogenesis. CHEBI:16537 galactarate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16537 CHEBI:16535 piperazine-2,5-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16535 GO:0051390 inactivation of MAPKKK activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051390 inactivation of MAP kinase kinase kinase activity|termination of MAP kinase kinase kinase activity|termination of MAPKKK activity Any process that terminates the activity of the active enzyme MAP kinase kinase kinase (MAPKKK). CHEBI:16536 orcinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16536 CHEBI:16533 L-tryptophanamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16533 CHEBI:16534 D-galactonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16534 GO:0051393 alpha-actinin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051393 alpha-actinin 4 binding|alpha-actinin 1 binding|nonmuscle alpha-actinin binding Interacting selectively and non-covalently with alpha-actinin, one of a family of proteins that cross-link F-actin as antiparallel homodimers. Alpha-actinin has a molecular mass of 93-103 KDa; at the N-terminus there are two calponin homology domains, at the C-terminus there are two EF-hands. These two domains are connected by the rod domain. This domain is formed by triple-helical spectrin repeats. CHEBI:16531 Renilla luciferin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16531 GO:0051394 regulation of nerve growth factor receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051394 regulation of NGF receptor activity Any process that modulates the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor. CHEBI:16532 N-benzyloxycarbonylglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16532 GO:0051391 tRNA acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051391 The modification of tRNA structure by addition of an acetyl group to tRNA. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid. CHEBI:16530 3-methyl-2-oxobutanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16530 GO:0051392 tRNA N-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051392 tRNA cytidine N-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + cytidine = CoA + N4-acetylcytidine. The cytidine is within the polynucleotide chain of a tRNA. GO:0051397 obsolete N-terminal basic amino acid aminopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051397 N-terminal basic amino acid aminopeptidase activity OBSOLETE. Catalysis of the hydrolysis of basic amino acid residues at the N-terminal of an oligopeptide or polypeptide chain. GO:0051398 obsolete N-terminal lysine aminopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051398 N-terminal lysine aminopeptidase activity|lysine aminopeptidase activity|lysyl aminopeptidase activity OBSOLETE. Catalysis of the hydrolysis of a lysine residue from the N-terminal of an oligopeptide or polypeptide chain. GO:0051395 negative regulation of nerve growth factor receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051395 downregulation of nerve growth factor receptor activity|down-regulation of nerve growth factor receptor activity|negative regulation of NGF receptor activity|inhibition of nerve growth factor receptor activity|down regulation of nerve growth factor receptor activity Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor. GO:0051396 positive regulation of nerve growth factor receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051396 up regulation of nerve growth factor receptor activity|activation of nerve growth factor receptor activity|stimulation of nerve growth factor receptor activity|positive regulation of NGF receptor activity|up-regulation of nerve growth factor receptor activity|upregulation of nerve growth factor receptor activity Any process that activates or increases the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor. CHEBI:41509 cholesteryl linoleate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_41509 GO:2000717 positive regulation of maintenance of mitotic sister chromatid cohesion, arms biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000717 positive regulation of maintenance of sister chromatin cohesion along arms at mitosis|positive regulation of maintenance of mitotic sister chromatin cohesion along arms Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion along the chromosome arms. GO:2000718 regulation of maintenance of mitotic sister chromatid cohesion, centromeric biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000718 regulation of maintenance of centromeric mitotic sister chromatin cohesion|regulation of maintenance of sister chromatin cohesion at centromere at mitosis|regulation of maintenance of mitotic sister chromatin cohesion at centromere Any process that modulates the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion in the centromeric region. GO:2000719 negative regulation of maintenance of mitotic sister chromatid cohesion, centromeric biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000719 negative regulation of maintenance of mitotic sister chromatin cohesion at centromere|negative regulation of maintenance of sister chromatin cohesion at centromere at mitosis|negative regulation of maintenance of centromeric mitotic sister chromatin cohesion Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion in the centromeric region. GO:2000710 negative regulation of maintenance of meiotic sister chromatid cohesion, centromeric biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000710 negative regulation of maintenance of meiotic sister chromatin cohesion at centromere|negative regulation of maintenance of sister chromatin cohesion at centromere at meiosis I|negative regulation of maintenance of centromeric meiotic sister chromatin cohesion Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion in the centromeric region. GO:2000711 positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000711 positive regulation of maintenance of centromeric meiotic sister chromatin cohesion|positive regulation of maintenance of sister chromatin cohesion at centromere at meiosis I|positive regulation of maintenance of meiotic sister chromatin cohesion at centromere Any process that activates or increases the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion in the centromeric region. GO:2000712 regulation of maintenance of meiotic sister chromatid cohesion, arms biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000712 regulation of maintenance of sister chromatin cohesion along arms at meiosis I|regulation of maintenance of meiotic sister chromatin cohesion along arms Any process that modulates the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion along the chromosome arms. GO:2000713 negative regulation of maintenance of meiotic sister chromatid cohesion, arms biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000713 negative regulation of maintenance of meiotic sister chromatin cohesion along arms|negative regulation of maintenance of sister chromatin cohesion along arms at meiosis I Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion along the chromosome arms. GO:2000714 positive regulation of maintenance of meiotic sister chromatid cohesion, arms biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000714 positive regulation of maintenance of sister chromatin cohesion along arms at meiosis I|positive regulation of maintenance of meiotic sister chromatin cohesion along arms Any process that activates or increases the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion along the chromosome arms. GO:2000715 regulation of maintenance of mitotic sister chromatid cohesion, arms biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000715 regulation of maintenance of mitotic sister chromatin cohesion along arms|regulation of maintenance of sister chromatin cohesion along arms at mitosis Any process that modulates the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion along the chromosome arms. GO:2000716 negative regulation of maintenance of mitotic sister chromatid cohesion, arms biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000716 negative regulation of maintenance of sister chromatin cohesion along arms at mitosis|negative regulation of maintenance of mitotic sister chromatin cohesion along arms Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion along the chromosome arms. CHEBI:16526 carbon dioxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16526 CHEBI:16524 testosterone acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16524 CHEBI:16525 taurochenodeoxycholic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16525 CHEBI:16522 trans-zeatin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16522 CHEBI:16523 D-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16523 CHEBI:16520 R'C(R)SH biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16520 CHEBI:16521 lanosterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16521 GO:2000728 regulation of mRNA export from nucleus in response to heat stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000728 regulation of mRNA export from cell nucleus during heat stress|regulation of mRNA export from nucleus during heat stress Any process that modulates the frequency, rate or extent of mRNA export from nucleus in response to heat stress. GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000729 positive regulation of ureteral mesenchymal cell proliferation|positive regulation of ureter mesenchymal cell proliferation Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in ureter development. GO:2000720 positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000720 positive regulation of maintenance of centromeric mitotic sister chromatin cohesion|positive regulation of maintenance of mitotic sister chromatin cohesion at centromere|positive regulation of maintenance of sister chromatin cohesion at centromere at mitosis Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion in the centromeric region. GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000721 positive regulation of transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|activation of global transcription from RNA polymerase II promoter of smooth muscle cell differentiation|activation of global transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|up regulation of transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|up-regulation of transcription from RNA polymerase II promoter of smooth muscle cell differentiation|positive regulation of global transcription from Pol II promoter of smooth muscle cell differentiation|stimulation of global transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|positive regulation of transcription from RNA polymerase II promoter, global of smooth muscle cell differentiation|positive regulation of transcription from Pol II promoter of smooth muscle cell differentiation|up-regulation of global transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|up regulation of global transcription from RNA polymerase II promoter of smooth muscle cell differentiation|upregulation of global transcription from RNA polymerase II promoter of smooth muscle cell differentiation|positive regulation of gene-specific transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|upregulation of global transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|positive regulation of transcription from Pol II promoter of nonstriated muscle cell differentiation|positive regulation of gene-specific transcription from RNA polymerase II promoter of smooth muscle cell differentiation|up regulation of transcription from RNA polymerase II promoter of smooth muscle cell differentiation|up-regulation of transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|positive regulation of transcription from RNA polymerase II promoter of smooth muscle cell differentiation|stimulation of transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|up regulation of global transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|up-regulation of global transcription from RNA polymerase II promoter of smooth muscle cell differentiation|activation of transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|activation of transcription from RNA polymerase II promoter of smooth muscle cell differentiation|positive regulation of transcription from RNA polymerase II promoter, global of nonstriated muscle cell differentiation|stimulation of global transcription from RNA polymerase II promoter of smooth muscle cell differentiation|stimulation of transcription from RNA polymerase II promoter of smooth muscle cell differentiation|positive regulation of global transcription from Pol II promoter of nonstriated muscle cell differentiation Any positive regulation of transcription from RNA polymerase II promoter that is involved in smooth muscle cell differentiation. GO:2000722 regulation of cardiac vascular smooth muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000722 regulation of heart vascular smooth muscle cell differentiation Any process that modulates the frequency, rate or extent of cardiac vascular smooth muscle cell differentiation. GO:2000723 negative regulation of cardiac vascular smooth muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000723 negative regulation of heart vascular smooth muscle cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of cardiac vascular smooth muscle cell differentiation. GO:2000724 positive regulation of cardiac vascular smooth muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000724 positive regulation of heart vascular smooth muscle cell differentiation Any process that activates or increases the frequency, rate or extent of cardiac vascular smooth muscle cell differentiation. GO:2000725 regulation of cardiac muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000725 regulation of cardiomyocyte differentiation|regulation of heart muscle cell differentiation Any process that modulates the frequency, rate or extent of cardiac muscle cell differentiation. GO:2000726 negative regulation of cardiac muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000726 negative regulation of cardiomyocyte differentiation|negative regulation of heart muscle cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell differentiation. GO:2000727 positive regulation of cardiac muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000727 positive regulation of cardiomyocyte differentiation|positive regulation of heart muscle cell differentiation Any process that activates or increases the frequency, rate or extent of cardiac muscle cell differentiation. CHEBI:16557 quercetin 3,3',7-trissulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16557 CHEBI:16558 triacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16558 CHEBI:16555 ethanethioic S-acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16555 CHEBI:16556 CMP-N-acetyl-beta-neuraminic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16556 CHEBI:16553 UDP-4-dehydro-6-deoxy-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16553 CHEBI:16554 sym-homospermidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16554 CHEBI:16551 alpha,alpha-trehalose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16551 CHEBI:16552 N-formyl-L-methionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16552 CHEBI:16550 xanthommatin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16550 GO:2000739 regulation of mesenchymal stem cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000739 Any process that modulates the frequency, rate or extent of mesenchymal stem cell differentiation. PR:000037070 phosphoprotein biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000037070 Prot/PhosRes+|phosphorylated protein A protein that includes at least one phosphorylated residue. GO:2000731 negative regulation of termination of RNA polymerase I transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000731 negative regulation of transcription termination from Pol I promoter|negative regulation of RNA polymerase I transcription termination|negative regulation of transcription termination from RNA polymerase I promoter Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase I transcription. GO:2000732 positive regulation of termination of RNA polymerase I transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000732 positive regulation of transcription termination from Pol I promoter|positive regulation of RNA polymerase I transcription termination|positive regulation of transcription termination from RNA polymerase I promoter Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase I transcription. GO:2000733 regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000733 regulation of glial cell line-derived neurotrophic factor receptor signalling pathway of ureteric bud formation|regulation of glial cell-derived neurotrophic factor receptor signalling pathway of ureteric bud formation|regulation of glial cell-derived neurotrophic factor receptor signaling pathway of ureteric bud formation|regulation of GDNF receptor signaling pathway of ureteric bud formation|regulation of glial cell derived neurotrophic factor receptor signaling pathway of ureteric bud formation Any process that modulates the frequency, rate or extent of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation. GO:2000734 negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000734 negative regulation of glial cell-derived neurotrophic factor receptor signalling pathway of ureteric bud formation|negative regulation of GDNF receptor signaling pathway of ureteric bud formation|negative regulation of glial cell derived neurotrophic factor receptor signaling pathway of ureteric bud formation|negative regulation of glial cell line-derived neurotrophic factor receptor signalling pathway of ureteric bud formation|negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway of ureteric bud formation Any process that stops, prevents or reduces the frequency, rate or extent of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation. GO:2000735 positive regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000735 positive regulation of GDNF receptor signaling pathway of ureteric bud formation|positive regulation of glial cell-derived neurotrophic factor receptor signalling pathway of ureteric bud formation|positive regulation of glial cell derived neurotrophic factor receptor signaling pathway of ureteric bud formation|positive regulation of glial cell line-derived neurotrophic factor receptor signalling pathway of ureteric bud formation|positive regulation of glial cell-derived neurotrophic factor receptor signaling pathway of ureteric bud formation Any process that activates or increases the frequency, rate or extent of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation. GO:2000736 regulation of stem cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000736 Any process that modulates the frequency, rate or extent of stem cell differentiation. GO:2000737 negative regulation of stem cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000737 Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation. GO:2000738 positive regulation of stem cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000738 Any process that activates or increases the frequency, rate or extent of stem cell differentiation. CHEBI:16548 chlordecone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16548 CHEBI:16549 UDP-2-acetamido-4-amino-2,4,6-trideoxy-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16549 CHEBI:16546 1-O-sinapoyl-beta-D-glucose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16546 CHEBI:16547 coniferyl aldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16547 CHEBI:16544 UDP-N-acetyl-D-galactosamine 4,6-bissulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16544 GO:2000730 regulation of termination of RNA polymerase I transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000730 regulation of RNA polymerase I transcription termination|regulation of transcription termination from RNA polymerase I promoter|regulation of transcription termination from Pol I promoter Any process that modulates the frequency, rate or extent of termination of RNA polymerase I transcription. CHEBI:16545 5-valerolactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16545 CHEBI:16542 L-serine phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16542 CHEBI:16543 N(2)-acetyl-L-ornithine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16543 CHEBI:16540 pyridin-2-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16540 IAO:0000103 failed exploratory term biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/IAO_0000103 The term was used in an attempt to structure part of the ontology but in retrospect failed to do a good job CHEBI:16541 protein polypeptide chain biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16541 UBERON:0008114 joint of girdle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008114 girdle joint A skeletal joint that is part of a appendage girdle region. UBERON:0008115 surface of cartilage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008115 cartilage surface A anatomical surface that is part of a cartilage element. GO:0002346 B cell positive selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002346 B lymphocyte positive selection|B-lymphocyte positive selection|B-cell positive selection Any process in which B cells are selected to survive based on signaling through the B cell antigen receptor. GO:0002347 response to tumor cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002347 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a tumor cell. GO:0002348 central B cell positive selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002348 central B-cell positive selection|central B lymphocyte positive selection|central B-lymphocyte positive selection Any process leading to positive selection of B cells in the bone marrow. Positive selection is the process in which B or T cells are selected to survive based on signaling through their antigen receptors. GO:0002349 histamine production involved in inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002349 histamine production involved in acute inflammatory response The synthesis or release of histamine following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. GO:0002342 central B cell deletion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002342 central B lymphocyte deletion|central B-lymphocyte deletion|central B-cell deletion The deletion of B cells by apoptotic process occurring as part of central tolerance induction and B cell selection. GO:0002343 peripheral B cell selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002343 peripheral B-cell selection|peripheral B-lymphocyte selection|peripheral B lymphocyte selection Any B cell selection process that occurs in the periphery. GO:0002344 B cell affinity maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002344 B-cell affinity maturation|B-lymphocyte affinity maturation|B lymphocyte affinity maturation The process in which B cells produce antibodies with increased antigen affinity. This is accomplished by somatic hypermutation and selection for B cells which produce higher affinity antibodies to antigen. GO:0002345 peripheral B cell receptor editing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002345 peripheral B-lymphocyte receptor editing|peripheral B-cell receptor editing|peripheral B lymphocyte receptor editing The process that takes place mainly in germinal center B cells in which a large number of mutations are generated in the heavy chain and light chain V-region genes and their immediately surrounding introns in order to increase antibody diversity and contribute to affinity maturation. GO:0002340 central B cell selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002340 central B-cell selection|central B-lymphocyte selection|central B lymphocyte selection Any B cell selection process that occurs in the bone marrow. GO:0002341 central B cell anergy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002341 central B lymphocyte anergy|central B-lymphocyte anergy|central B-cell anergy Any process contributing to anergy, a state of functional inactivation that occurs as part of tolerance induction, in B cells in the bone marrow. GO:0016987 sigma factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016987 sigma transcription factor|plastid sigma factor activity|DNA-dependent RNA polymerase promoter selection factor|sigma factor activity|promoter selection factor activity|bacterial sigma factor activity|core DNA-dependent RNA polymerase binding promoter specificity activity Sigma factors act as the promoter specificity subunit of eubacterial and plant plastid multisubunit RNA polymerases, whose core subunit composition is often described as alpha(2)-beta-beta-prime. Although sigma does not bind DNA on its own, when combined with the core to form the holoenzyme, the sigma factor binds specifically to promoter elements. The sigma subunit is released once elongation begins. GO:0016988 obsolete transcription initiation factor antagonist activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016988 transcription initiation factor antagonist activity|transcriptional initiation factor antagonist activity OBSOLETE. The function of binding to a transcription factor and stopping, preventing or reducing the rate of its transcriptional activity. GO:0016989 sigma factor antagonist activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016989 anti-sigma factor activity The function of binding to a sigma factor and stopping, preventing or reducing the rate of its transcriptional activity. GO:0016983 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016983 GO:0016984 ribulose-bisphosphate carboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016984 EC:4.1.1.39|RHEA:23124|MetaCyc:RIBULOSE-BISPHOSPHATE-CARBOXYLASE-RXN rubisco activity|ribulose 1,5-diphosphate carboxylase activity|ribulose 1,5-bisphosphate carboxylase activity|ribulose 1,5-diphosphate carboxylase/oxygenase activity|carboxydismutase activity|D-ribulose-1,5-bisphosphate carboxylase activity|RuBisCO activity|D-ribulose 1,5-diphosphate carboxylase activity|RuBP carboxylase activity|3-phospho-D-glycerate carboxy-lyase (dimerizing; D-ribulose-1,5-bisphosphate-forming)|diphosphoribulose carboxylase activity|ribulose bisphosphate carboxylase/oxygenase activity|ribulose diphosphate carboxylase activity|ribulose diphosphate carboxylase/oxygenase activity|3-phospho-D-glycerate carboxy-lyase (dimerizing)|ribulose 1,5-bisphosphate carboxylase/oxygenase activity Catalysis of the reaction: D-ribulose 1,5-bisphosphate + CO2 + H2O = 2 3-phospho-D-glycerate. CHEBI:90437 phosphatidylserine(18:1/18:1) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90437 GO:0016985 mannan endo-1,4-beta-mannosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016985 EC:3.2.1.78|MetaCyc:3.2.1.78-RXN beta-1,4-mannan 4-mannanohydrolase activity|endo-beta-mannanase activity|1,4-beta-D-mannan mannanohydrolase activity|beta-mannanase B|beta-mannanase activity|endo-1,4-beta-mannanase activity|endo-beta-1,4-mannase activity|endo-1,4-mannanase activity|beta-D-mannanase activity Catalysis of the random hydrolysis of (1->4)-beta-D-mannosidic linkages in mannans, galactomannans, glucomannans, and galactoglucomannans. GO:0016986 obsolete transcription initiation factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016986 transcription initiation factor activity|transcriptional initiation factor activity OBSOLETE. Plays a role in regulating transcription initiation. CHEBI:90432 phosphatidylinositol(18:0/20:4) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90432 GO:0016980 creatinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016980 MetaCyc:CREATINASE-RXN|KEGG_REACTION:R01566|RHEA:22456|EC:3.5.3.3 creatine amidinohydrolase activity Catalysis of the reaction: creatine + H(2)O = sarcosine + urea. CHEBI:90433 phosphatidylserine(18:0/18:1) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90433 CHEBI:90434 phosphatidylserine(18:0/18:2) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90434 GO:0016982 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016982 CHEBI:90430 phosphatidylinositol(16:0/20:4) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90430 IAO:0000078 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/IAO_0000078 CHEBI:90431 phosphatidylinositol(18:0/18:2) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90431 GO:0002357 defense response to tumor cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002357 Reactions triggered in response to the presence of a tumor cell that act to protect the cell or organism. GO:0002358 B cell homeostatic proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002358 B-cell homeostatic proliferation|B-lymphocyte homeostatic proliferation|B lymphocyte homeostatic proliferation The non-specific expansion of B cell populations within a whole or part of an organism to reach to a total number of B cells which will then remain stable over time in the absence of an external stimulus. GO:0002359 B-1 B cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002359 B-1 B-cell proliferation|B-1 B-lymphocyte proliferation|B-1 B lymphocyte proliferation The expansion of a B-1 B cell by cell division. Follows B cell activation. GO:0002353 plasma kallikrein-kinin cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002353 A series of reactions that takes place outside the cell occurring in response to tissue damage and initiated within blood plasma by the action of activated Factor XII (Hageman Factor) on prekallikrein to convert it to plasma kallikrein, and the subsequent reaction of plasma kallikrein with high molecular weight kininogen. The ultimate product of the plasma kallikrein-kinin cascade is bradykinin, an agent known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability. GO:0002354 central B cell negative selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002354 central B-lymphocyte negative selection|central B-cell negative selection|central B lymphocyte negative selection Any process leading to negative selection of B cells in the bone marrow. GO:0002355 detection of tumor cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002355 The series of events in which a stimulus from a tumor cell is received and converted into a molecular signal. GO:0002356 peripheral B cell negative selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002356 peripheral B-lymphocyte negative selection|peripheral B-cell negative selection|peripheral B lymphocyte negative selection Any process leading to negative selection of B cells in the periphery. GO:0002350 peripheral B cell positive selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002350 peripheral B-cell positive selection|peripheral B lymphocyte positive selection|peripheral B-lymphocyte positive selection Any process leading to positive selection of B cells in the periphery. Positive selection is the process in which B or T cells are selected to survive based on signaling through their antigen receptors. GO:0002351 serotonin production involved in inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002351 serotonin production involved in acute inflammatory response The synthesis or release of serotonin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. GO:0002352 B cell negative selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002352 B-lymphocyte negative selection|B-cell negative selection|B lymphocyte negative selection Any process leading to negative selection in B cells. Mechanisms of negative selection include anergy and deletion. GO:0016998 cell wall macromolecule catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016998 cellular cell wall macromolecule catabolism|cellular cell wall macromolecule degradation|cell wall degradation|cell wall breakdown|cellular cell wall macromolecule breakdown|cellular cell wall macromolecule catabolic process|cell wall catabolism The chemical reactions and pathways resulting in the breakdown of macromolecules that form part of a cell wall. GO:0016999 antibiotic metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016999 antibiotic metabolism The chemical reactions and pathways involving an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms. GO:0016994 precorrin-6A reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016994 MetaCyc:1.3.1.54-RXN|RHEA:23408|EC:1.3.1.54 precorrin-6Y:NADP+ oxidoreductase activity|precorrin-6Y:NADP(+) oxidoreductase activity|precorrin-6X reductase activity|precorrin-6B:NADP+ oxidoreductase activity Catalysis of the reaction: precorrin-6B + NADP+ = precorrin-6A + NADPH + H+. GO:0016995 cholesterol oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016995 EC:1.1.3.6|MetaCyc:CHOLESTEROL-OXIDASE-RXN|RHEA:21328|KEGG_REACTION:R01459 3beta-hydroxysteroid:oxygen oxidoreductase activity|cholesterol- O2 oxidoreductase activity|3beta-hydroxy steroid oxidoreductase activity|cholesterol-O2 oxidoreductase activity|cholesterol-O(2) oxidoreductase activity|cholesterol:oxygen oxidoreductase activity Catalysis of the reaction: cholesterol + O2 = cholest-5-en-3-one + H2O2. GO:0016996 endo-alpha-(2,8)-sialidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016996 EC:3.2.1.129|MetaCyc:3.2.1.129-RXN polysialoside (2->8)-alpha-sialosylhydrolase activity|endo-N-acetylneuraminidase activity|poly(alpha-2,8-sialoside) alpha-2,8-sialosylhydrolase activity|endoneuraminidase activity|poly(alpha-2,8-sialosyl) endo-N-acetylneuraminidase activity|alpha-2,8-sialosylhydrolase activity|endosialidase activity|endo-N-acylneuraminidase activity Catalysis of the endohydrolysis of (2->8)-alpha-sialosyl linkages in oligo- or poly(sialic) acids. GO:0016997 alpha-sialidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016997 Catalysis of the hydrolysis of alpha-glycosidic linkages in oligo- or poly(sialic) acids. GO:0016990 arginine deiminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016990 RHEA:19597|MetaCyc:ARGININE-DEIMINASE-RXN|EC:3.5.3.6 L-arginine iminohydrolase activity|L-arginine deiminase activity|arginine dihydrolase activity|citrulline iminase activity Catalysis of the reaction: L-arginine + H2O = L-citrulline + NH3. GO:0016991 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016991 GO:0016992 lipoate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016992 RHEA:16585|Reactome:R-HSA-6793591|EC:2.8.1.8|MetaCyc:RXN0-949 lipoyl synthase activity|LS|protein 6-N-(octanoyl)lysine:sulfur sulfurtransferase activity|lipoic acid synthase|protein N6-(octanoyl)lysine:sulfur sulfurtransferase activity|LipA Catalysis of the reaction: protein N6-(octanoyl)lysine + 2 sulfur + 2 S-adenosyl-L-methionine = protein N6-(lipoyl)lysine + 2 L-methionine + 2 5'-deoxyadenosyl. GO:0016993 precorrin-8X methylmutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016993 EC:5.4.99.61|RHEA:22512|MetaCyc:5.4.1.2-RXN precorrin-8X 11,12-methylmutase activity|hydrogenobyrinic acid-binding protein activity|HBA synthase activity|precorrin isomerase activity Catalysis of the reaction: precorrin-8X = hydrogenobyrinate. CHEBI:90420 N(6)-(3-O-phospho-D-ribulosyl)-L-lysinium residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90420 GO:0002324 natural killer cell proliferation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002324 NK cell proliferation during immune response|natural killer cell proliferation during immune response The expansion of a natural killer cell population by cell division as part of an immune response. GO:0002325 natural killer cell differentiation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002325 natural killer cell development involved in immune response|natural killer cell differentiation during immune response|NK cell differentiation during immune response The process in which a naive natural killer cell acquires the specialized features of an effector natural killer T cell as part of an immune response. GO:0002326 B cell lineage commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002326 B lymphocyte lineage commitment|B-lymphocyte lineage commitment|B-cell lineage commitment The process in which a lymphoid progenitor cell becomes committed to become any type of B cell. GO:0002327 immature B cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002327 immature B-cell differentiation|immature B-lymphocyte differentiation|immature B cell development|immature B lymphocyte differentiation The process in which a precursor cell type acquires the specialized features of an immature B cell. GO:0002320 lymphoid progenitor cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002320 The process in which a precursor cell type acquires the specialized features of a lymphoid progenitor cell. Lymphoid progenitor cells include progenitor cells for any of the lymphoid lineages. GO:0002321 natural killer cell progenitor differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002321 The process in which a precursor cell type acquires the specialized features of a natural killer cell progenitor. GO:0002322 B cell proliferation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002322 B-lymphocyte proliferation during immune response|B-cell proliferation during immune response|B cell proliferation during immune response|B lymphocyte proliferation during immune response The expansion of a B cell population by cell division following B cell activation during an immune response. GO:0002323 natural killer cell activation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002323 natural killer cell activation during immune response|NK cell activation during immune response The change in morphology and behavior of a natural killer cell resulting from exposure a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. CHEBI:41487 oxidized Oplophorus luciferin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_41487 GO:0016969 obsolete hemerythrin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016969 hemerythrin OBSOLETE. An oxygen carrier found in a few groups of invertebrates, e.g. sipunculid worms, certain molluscs, and crustaceans. CHEBI:41482 (R)-carnitinyl-CoA betaine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_41482 GO:0016965 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016965 GO:0016966 nitric oxide reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016966 RHEA:30211|EC:1.7.2.5|KEGG_REACTION:R00294|MetaCyc:NITRIC-OXIDE-REDUCTASE-RXN CYP55|nitrous-oxide:acceptor oxidoreductase (NO-forming)|nitrogen oxide reductase activity|cytochrome bc nitric oxide reductase activity|P450nor|nitric-oxide reductase activity|nitrous-oxide:(acceptor) oxidoreductase (NO-forming)|P450 nitric oxide reductase activity Catalysis of the reaction: H(2)O + 2 ferricytochrome c + nitrous oxide = 2 H(+) + 2 ferrocytochrome c + 2 nitric oxide. GO:0016967 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016967 GO:1905700 negative regulation of xenobiotic detoxification by transmembrane export across the plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905700 inhibition of drug transmembrane export|negative regulation of drug transmembrane export|down regulation of drug transmembrane export|downregulation of drug transmembrane export|down-regulation of drug transmembrane export|negative regulation of xenobiotic transmembrane export Any process that stops, prevents or reduces the frequency, rate or extent of drug transmembrane export. GO:0016968 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016968 GO:1905701 positive regulation of xenobiotic detoxification by transmembrane export across the plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905701 positive regulation of drug transmembrane export|upregulation of drug transmembrane export|up regulation of drug transmembrane export|positive regulation of xenobiotic transmembrane export|activation of drug transmembrane export|up-regulation of drug transmembrane export Any process that activates or increases the frequency, rate or extent of drug transmembrane export. GO:0016961 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016961 CHEBI:90458 PA(18:0/22:4) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90458 GO:1905702 regulation of inhibitory synapse assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905702 regulation of inhibitory synapse formation Any process that modulates the frequency, rate or extent of inhibitory synapse assembly. GO:0016962 obsolete receptor-associated protein activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016962 receptor-associated protein activity OBSOLETE. (Was not defined before being made obsolete). GO:1905703 negative regulation of inhibitory synapse assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905703 downregulation of inhibitory synapse assembly|inhibition of inhibitory synapse formation|down-regulation of inhibitory synapse assembly|inhibition of inhibitory synapse assembly|negative regulation of inhibitory synapse formation|down-regulation of inhibitory synapse formation|downregulation of inhibitory synapse formation|down regulation of inhibitory synapse assembly|down regulation of inhibitory synapse formation Any process that stops, prevents or reduces the frequency, rate or extent of inhibitory synapse assembly. GO:0016963 obsolete alpha-2 macroglobulin receptor-associated protein activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016963 alpha-2 macroglobulin receptor-associated protein activity OBSOLETE. Interaction with the alpha-2 macroglobulin receptor and glycoprotein gp330 forming a complex with the alpha-2 macroglobulin receptor light and heavy chains. GO:1905704 positive regulation of inhibitory synapse assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905704 upregulation of inhibitory synapse formation|up regulation of inhibitory synapse assembly|activation of inhibitory synapse assembly|up-regulation of inhibitory synapse formation|activation of inhibitory synapse formation|up-regulation of inhibitory synapse assembly|positive regulation of inhibitory synapse formation|up regulation of inhibitory synapse formation|upregulation of inhibitory synapse assembly Any process that activates or increases the frequency, rate or extent of inhibitory synapse assembly. GO:0016964 alpha-2 macroglobulin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016964 Combining with alpha-2 macroglobulin and delivering alpha-2 macroglobulin into the cell via receptor-mediated endocytosis. GO:1905705 cellular response to paclitaxel biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905705 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paclitaxel stimulus. CHEBI:90454 lysophosphatidylglycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90454 GO:1905706 regulation of mitochondrial ATP synthesis coupled proton transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905706 Any process that modulates the frequency, rate or extent of mitochondrial ATP synthesis coupled proton transport. GO:1905707 negative regulation of mitochondrial ATP synthesis coupled proton transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905707 Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial ATP synthesis coupled proton transport. CHEBI:90456 lysophosphatidylinositol 18:1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90456 GO:1905708 regulation of cell morphogenesis involved in conjugation with cellular fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905708 regulation of shmoo orientation|regulation of shmooing Any process that modulates the location, frequency, rate or extent of cell morphogenesis involved in conjugation with cellular fusion. CHEBI:90457 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-1,2-dioctoanoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90457 GO:0016960 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016960 GO:0002328 pro-B cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002328 pro-B cell development|pro-B lymphocyte differentiation The process in which a precursor cell type acquires the specialized features of a pro-B cell. Pro-B cells are the earliest stage of the B cell lineage and undergo heavy chain D and J gene rearrangements, although they are not fully committed. GO:1905709 negative regulation of membrane permeability biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905709 Any process that stops, prevents or reduces the frequency, rate or extent of the passage or uptake of molecules by a membrane. GO:0002329 pre-B cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002329 pre-B cell development|pre-B lymphocyte differentiation The process in which a precursor cell type acquires the specialized features of a pre-B cell. Pre-B cells follow the pro-B cell stage of immature B cell differentiation and undergo rearrangement of heavy chain V, D, and J gene segments. CHEBI:90452 lysophosphatidylethanolamine 16:0 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90452 CHEBI:90453 1,2-dioctanoyl-3-beta-D-galactosyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90453 GO:0051302 regulation of cell division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051302 Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells. GO:0002335 mature B cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002335 mature B lymphocyte differentiation|mature B-cell differentiation|mature B-lymphocyte differentiation|mature cell development The process in which transitional stage B cells acquire the specialized features of mature B cells in the spleen. GO:0051303 establishment of chromosome localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051303 chromosome positioning|establishment of chromosome localisation The directed movement of a chromosome to a specific location. GO:0002336 B-1 B cell lineage commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002336 B-1 B lymphocyte lineage commitment|B-1 B-lymphocyte lineage commitment|B-1 B-cell lineage commitment The process in which an immature B cell becomes committed to become a B-1 B cell. GO:0051300 spindle pole body organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051300 SPB organization|SPB maturation|spindle pole body maturation|spindle pole body organisation|spindle pole body organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle pole body (SPB). The SPB is the microtubule organizing center in fungi, and is functionally homologous to the animal cell centrosome. GO:0002337 B-1a B cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002337 B-1a B-cell differentiation|B-1a B-lymphocyte differentiation|B-1a B cell development|B-1a B lymphocyte differentiation The process in which B cells acquire the specialized features of B-1a B cells. B-1a B cells are B-1 cells that express CD5 and arise from fetal liver precursors. GO:0051301 cell division biolink:BiologicalProcess go-plus goslim_pir|goslim_drosophila|goslim_generic|goslim_chembl http://purl.obolibrary.org/obo/GO_0051301 Wikipedia:Cell_division The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells. GO:0002338 B-1b B cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002338 B-1b B-cell differentiation|B-1b B-lymphocyte differentiation|B-1b B cell development|B-1b B lymphocyte differentiation The process in which B cells acquire the specialized features of B-1b B cells. B-1b B cells are B-1 cells that do not express CD5. GO:0051306 mitotic sister chromatid separation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051306 mitotic sister chromatid resolution|mitotic chromosome separation|sister chromatid separation during mitosis|chromosome separation during mitosis The process in which sister chromatids are physically detached from each other during mitosis. GO:0002331 pre-B cell allelic exclusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002331 pre-B lymphocyte allelic exclusion Expression of a single heavy chain allele during pre-B cell differentiation. GO:0051307 meiotic chromosome separation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051307 chromosome separation during meiosis|meiotic chromosome resolution The process in which chromosomes are physically detached from each other during meiosis. GO:0002332 transitional stage B cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002332 transitional stage B-cell differentiation|transitional stage B-lymphocyte differentiation|transitional stage B cell development|transitional stage B lymphocyte differentiation The process in which immature B cells from the bone marrow become mature B cells in the spleen. Transitional stage B cells are subdivided into transitional one (T1) and transitional two (T2) stages and are short-lived and functionally incompetent. GO:0051304 chromosome separation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051304 rDNA separation|chromatid release The cell cycle process in which paired chromosomes are detached from each other. Chromosome separation begins with the release of cohesin complexes from chromosomes; in budding yeast, this includes the cleavage of cohesin complexes along the chromosome arms, followed by the separation of the centromeric regions. Chromosome separation also includes formation of chromatid axes mediated by condensins, and ends with the disentangling of inter-sister catenation catalyzed by topoisomerase II (topo II). GO:0002333 transitional one stage B cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002333 transitional one stage B-cell differentiation|transitional one stage B-lymphocyte differentiation|T1 stage B cell differentiation|transitional one stage B cell development|transitional one stage B lymphocyte differentiation The process in which immature B cells from the bone marrow acquire the specialized features of T1 stage B cells in the spleen. T1 stage B cells do not express either CD23 or CD21. GO:0002334 transitional two stage B cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002334 transitional two stage B cell development|transitional two stage B lymphocyte differentiation|T2 stage B cell differentiation|transitional two stage B-cell differentiation|transitional two stage B-lymphocyte differentiation The process in which immature B cells from the bone marrow acquire the specialized features of T2 stage B cells in the spleen. T2 stage B cells express CD23 but not CD21. GO:0051305 chromosome movement towards spindle pole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051305 chromosome movement|chromosome migration to spindle pole|chromosome movement to spindle pole The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes. GO:0051308 male meiosis chromosome separation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051308 male meiosis chromosome resolution|chromosome separation during male meiosis The process in which paired chromosomes are physically detached from each other during male meiosis. GO:0051309 female meiosis chromosome separation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051309 female meiosis chromosome resolution|chromosome separation during female meiosis The process in which paired chromosomes are physically detached from each other during female meiosis. GO:0002330 pre-B cell receptor expression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002330 The process leading up to expression of the pre-B cell receptor on the surface of pre-B cells, including expression of the surrogate light chain, association of the surrogate light chain with heavy chain, and expression of the complete pre-B cell receptor on the cell surface. GO:0016976 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016976 GO:0016977 chitosanase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016977 MetaCyc:3.2.1.132-RXN|EC:3.2.1.132 chitosan N-acetylglucosaminohydrolase activity Catalysis of the endohydrolysis of beta-1,4-linkages between N-acetyl-D-glucosamine and D-glucosamine residues in a partly acetylated chitosan. GO:1905710 positive regulation of membrane permeability biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905710 Any process that activates or increases the frequency, rate or extent of the passage or uptake of molecules by a membrane. GO:0016978 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016978 GO:0016979 lipoate-protein ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016979 EC:6.3.1.20|RHEA:49288|MetaCyc:RXN-13039|MetaCyc:RXN-8655|MetaCyc:RXN-8654|MetaCyc:RXN0-1141 lipoate-protein ligase activity (lipoylation of glycine cleavage complex)|lipoate-protein ligase A activity|lipoate-protein ligase B activity Catalysis of the lipoylation of a protein in two steps: ATP + (R)-lipoate + a [lipoyl-carrier protein]-L-lysine = a [lipoyl-carrier protein]-N6-(lipoyl)lysine + AMP + diphosphate (overall reaction): (1) ATP + (R)-lipoate = lipoyl-AMP + diphosphate; (2) lipoyl-AMP + a [lipoyl-carrier protein]-L-lysine = a [lipoyl-carrier protein]-N6-(lipoyl)lysine + AMP. GO:1905711 response to phosphatidylethanolamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905711 response to phosphatidyl(amino)ethanols|response to phosphatidylethanolamines|response to PtdEtn|response to PE Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phosphatidylethanolamine stimulus. GO:0016972 thiol oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016972 EC:1.8.3.2|UM-BBD_reactionID:r1293|RHEA:17357|MetaCyc:THIOL-OXIDASE-RXN thiol:oxygen oxidoreductase activity|sulfhydryl oxidase activity Catalysis of the reaction: 4 R'C(R)SH + O2 = 2 R'C(R)S-S(R)CR' + 2 H2O2. GO:1905712 cellular response to phosphatidylethanolamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905712 cellular response to phosphatidyl(amino)ethanols|cellular response to phosphatidylethanolamines|cellular response to PE|cellular response to PtdEtn Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phosphatidylethanolamine stimulus. GO:0016973 poly(A)+ mRNA export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016973 poly(A)+ mRNA transport from nucleus to cytoplasm|polyadenylated mRNA export from nucleus|poly(A) mRNA export from nucleus|poly(A)+ mRNA-nucleus export|poly(A)+ mRNA export out of nucleus|poly(A)+ mRNA export from cell nucleus The directed movement of poly(A)+ mRNA out of the nucleus into the cytoplasm. GO:1905713 obsolete mitochondrial calcium uptake involved in regulation of presynaptic cytosolic calcium ion concentration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905713 calcium ion transmembrane import into mitochondrion involved in regulation of presynaptic cytosolic calcium levels|mitochondrial calcium uptake involved in regulation of presynaptic cytosolic calcium levels|calcium ion transmembrane import into mitochondrion involved in regulation of presynaptic cytosolic calcium ion concentration OBSOLETE. Any mitochondrial calcium uptake that is involved in regulation of presynaptic cytosolic calcium ion concentration. GO:1905714 obsolete mitochondrial calcium release involved in regulation of presynaptic cytosolic calcium ion concentration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905714 mitochondrial calcium release involved in regulation of presynaptic cytosolic calcium levels|calcium ion transmembrane export from mitochondrion involved in regulation of presynaptic cytosolic calcium ion concentration|calcium ion transmembrane export from mitochondrion involved in regulation of presynaptic cytosolic calcium levels OBSOLETE. Any mitochondrial calcium release that is involved in regulation of presynaptic cytosolic calcium ion concentration. GO:0016974 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016974 GO:1905715 regulation of cornification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905715 Any process that modulates the frequency, rate or extent of cornification. GO:0016975 obsolete alpha-2 macroglobulin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016975 alpha-2 macroglobulin OBSOLETE. Inhibition of proteinase by a mechanism involving a bait region which contains specific sites, cleavage of which induces a conformational change that results in trapping of the proteinase; following cleavage in the bait region a thiolester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase; subsequently epsilon-amino groups of the proteinase react with thiolester linkages in the inhibitor to form stable amide links; the entrapped proteinase can now only act on low molecular mass substrates. GO:1905716 negative regulation of cornification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905716 down regulation of cornification|downregulation of cornification|down-regulation of cornification|inhibition of cornification Any process that stops, prevents or reduces the frequency, rate or extent of cornification. GO:1905717 positive regulation of cornification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905717 upregulation of cornification|up regulation of cornification|activation of cornification|up-regulation of cornification Any process that activates or increases the frequency, rate or extent of cornification. GO:1905718 obsolete mitotic spindle astral microtubule end biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1905718 mitotic spindle astral microtubule tip OBSOLETE. Any microtubule end that is part of a mitotic spindle astral microtubule. GO:0016970 obsolete hemocyanin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016970 hemocyanin OBSOLETE. A blue, copper-containing oxygen carrier present in many molluscs and arthropods. GO:1905719 protein localization to perinuclear region of cytoplasm biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905719 protein localisation to perinuclear region of cytoplasm|protein localization to perinuclear cytoplasm|protein localization in perinuclear region of cytoplasm|protein localisation in perinuclear region of cytoplasm A process in which a protein is transported to, or maintained in, a location within the perinuclear region of the cytoplasm. GO:0016971 flavin-linked sulfhydryl oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016971 Catalysis of the formation of disulfide bridges. GO:0002339 B cell selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002339 B-cell selection|B-lymphocyte selection|B lymphocyte selection The process dependent upon B cell antigen receptor signaling in response to self or foreign antigen through which B cells are selected for survival. GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002302 CD8-positive, alpha-beta T lymphocyte differentiation during immune response|CD8-positive, alpha-beta T cell differentiation during immune response|CD8-positive, alpha-beta T-lymphocyte differentiation during immune response|CD8-positive, alpha-beta T-cell differentiation during immune response|CD8-positive, alpha-beta intraepithelial T cell development The process in which an antigenically naive CD8-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells. GO:0051313 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051313 GO:0002303 gamma-delta T cell differentiation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002303 gamma-delta T-lymphocyte differentiation during immune response|gamma-delta T cell differentiation during immune response|gamma-delta T-cell differentiation during immune response|gamma-delta T cell development involved in immune response|gamma-delta T lymphocyte differentiation during immune response The process in which an antigenically naive gamma-delta T cell acquires the specialized features of an effector, regulatory, or memory T cell and contributes to an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells. GO:0051314 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051314 GO:0002304 gamma-delta intraepithelial T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002304 gamma-delta intraepithelial T-lymphocyte differentiation|gamma-delta intraepithelial T cell development|gamma-delta intraepithelial T lymphocyte differentiation|gamma-delta intraepithelial T-cell differentiation The process in which a precursor cell type acquires the specialized features of a gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways. GO:0051311 meiotic metaphase plate congression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051311 metaphase plate congression during meiosis The cell cycle process in which chromosomes are aligned at the metaphase plate, a plane halfway between the poles of the meiotic spindle, during meiosis. GO:0002305 CD8-positive, gamma-delta intraepithelial T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002305 CD8-positive, gamma-delta intraepithelial T cell development|CD8-positive, gamma-delta intraepithelial T lymphocyte differentiation|CD8-positive, gamma-delta intraepithelial T-cell differentiation|CD8-positive, gamma-delta intraepithelial T-lymphocyte differentiation The process in which a precursor cell type acquires the specialized features of a CD8-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways. GO:0051312 chromosome decondensation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051312 The alteration of chromosome structure from the condensed form to a relaxed disperse form. GO:0051317 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051317 GO:0051318 G1 phase biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0051318 Wikipedia:G1_phase The cell cycle 'gap' phase which is the interval between the completion of DNA segregation (usually by mitosis or meiosis) and the beginning of DNA synthesis. CHEBI:89484 4-heptanone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_89484 GO:0002300 CD8-positive, alpha-beta intraepithelial T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002300 CD8-positive, alpha-beta intraepithelial T-cell differentiation|CD8-positive, alpha-beta intraepithelial T-lymphocyte differentiation|CD8-positive, alpha-beta intraepithelial T cell development|CD8-positive, alpha-beta intraepithelial T lymphocyte differentiation The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways. GO:0051315 attachment of mitotic spindle microtubules to kinetochore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051315 attachment of spindle microtubules to mitotic chromosome|attachment of spindle microtubules to kinetochore during mitosis|attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|attachment of spindle microtubules to kinetochore involved in mitosis|mitotic bipolar attachment The cell cycle process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex as part of mitotic metaphase plate congression. GO:0002301 CD4-positive, alpha-beta intraepithelial T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002301 CD4-positive, alpha-beta intraepithelial T lymphocyte differentiation|CD4-positive, alpha-beta intraepithelial T-cell differentiation|CD4-positive, alpha-beta intraepithelial T-lymphocyte differentiation|CD4-positive, alpha-beta intraepithelial T cell development The process in which a precursor cell type acquires the specialized features of a CD4-positive, alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways. GO:0051316 attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051316 attachment of spindle microtubules to meiotic chromosome|attachment of spindle microtubules to kinetochore during meiotic chromosome segregation|attachment of spindle microtubules to kinetochore during meiosis The cell cycle process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex contributing to meiotic chromosome segregation. GO:2000786 positive regulation of autophagosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000786 positive regulation of autophagic vacuole formation|positive regulation of PAS formation|positive regulation of autophagosome biosynthesis|positive regulation of autophagosome formation|positive regulation of autophagic vacuole assembly Any process that activates or increases the frequency, rate or extent of autophagic vacuole assembly. UBERON:6001730 larval head biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_6001730 Any head that is part of some larva. GO:2000787 regulation of venous endothelial cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000787 Any process that modulates the frequency, rate or extent of venous endothelial cell fate commitment. GO:2000788 negative regulation of venous endothelial cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000788 Any process that stops, prevents or reduces the frequency, rate or extent of venous endothelial cell fate commitment. GO:0051319 G2 phase biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0051319 Wikipedia:G2_phase The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation (usually by mitosis or meiosis). GO:2000789 positive regulation of venous endothelial cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000789 Any process that activates or increases the frequency, rate or extent of venous endothelial cell fate commitment. GO:0016947 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016947 GO:0016948 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016948 GO:0016949 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016949 UBERON:6001732 larval head segment biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_6001732 Any segment that is part of some larval head. GO:0016943 obsolete RNA polymerase I transcription elongation factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016943 RNA polymerase I transcription elongation factor activity|Pol I transcription elongation factor activity OBSOLETE. Any activity that modulates the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule catalyzed by RNA polymerase I following transcription initiation. GO:0016944 obsolete RNA polymerase II transcription elongation factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016944 RNA polymerase II transcription elongation factor activity|Pol II transcription elongation factor activity OBSOLETE. Any activity that modulates the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule catalyzed by RNA polymerase II following transcription initiation. GO:1905720 cytoplasmic microtubule bundle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1905720 microtubule fascicle of cytoplasm|microtubule bundle of cytoplasm Any microtubule bundle that is part of a cytoplasm. GO:2000780 negative regulation of double-strand break repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000780 Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair. GO:0016945 obsolete RNA polymerase III transcription elongation factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016945 RNA polymerase III transcription elongation factor activity|Pol III transcription elongation factor activity OBSOLETE. Any activity that modulates the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule catalyzed by RNA polymerase III following transcription initiation. GO:1905721 mitotic spindle astral microtubule end biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1905721 mitotic spindle astral microtubule tip Any microtubule end that is part of a mitotic spindle astral microtubule. GO:2000781 positive regulation of double-strand break repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000781 Any process that activates or increases the frequency, rate or extent of double-strand break repair. GO:1905722 regulation of trypanothione biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905722 regulation of trypanothione anabolism|regulation of trypanothione biosynthesis|regulation of trypanothione synthesis|regulation of trypanothione formation Any process that modulates the frequency, rate or extent of trypanothione biosynthetic process. GO:0016946 obsolete cathepsin F activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016946 cathepsin F activity OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Cleavage of substrates with Phe and Leu in P2. GO:1905723 negative regulation of trypanothione biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905723 negative regulation of trypanothione synthesis|down-regulation of trypanothione synthesis|inhibition of trypanothione anabolism|down-regulation of trypanothione formation|negative regulation of trypanothione formation|inhibition of trypanothione synthesis|down-regulation of trypanothione biosynthetic process|down-regulation of trypanothione biosynthesis|negative regulation of trypanothione biosynthesis|inhibition of trypanothione formation|down regulation of trypanothione anabolism|downregulation of trypanothione biosynthesis|downregulation of trypanothione biosynthetic process|down regulation of trypanothione synthesis|downregulation of trypanothione anabolism|down regulation of trypanothione biosynthetic process|down regulation of trypanothione biosynthesis|inhibition of trypanothione biosynthesis|inhibition of trypanothione biosynthetic process|down regulation of trypanothione formation|downregulation of trypanothione synthesis|downregulation of trypanothione formation|negative regulation of trypanothione anabolism|down-regulation of trypanothione anabolism Any process that stops, prevents or reduces the frequency, rate or extent of trypanothione biosynthetic process. GO:2000782 regulation of establishment of cell polarity regulating cell shape biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000782 Any process that modulates the frequency, rate or extent of establishment of cell polarity regulating cell shape. GO:1905724 positive regulation of trypanothione biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905724 positive regulation of trypanothione formation|activation of trypanothione formation|up-regulation of trypanothione biosynthetic process|up-regulation of trypanothione biosynthesis|activation of trypanothione biosynthesis|activation of trypanothione biosynthetic process|up-regulation of trypanothione anabolism|up-regulation of trypanothione synthesis|up-regulation of trypanothione formation|positive regulation of trypanothione biosynthesis|upregulation of trypanothione anabolism|up regulation of trypanothione biosynthetic process|up regulation of trypanothione biosynthesis|upregulation of trypanothione synthesis|upregulation of trypanothione formation|up regulation of trypanothione anabolism|upregulation of trypanothione biosynthesis|positive regulation of trypanothione anabolism|upregulation of trypanothione biosynthetic process|activation of trypanothione anabolism|up regulation of trypanothione synthesis|positive regulation of trypanothione synthesis|activation of trypanothione synthesis|up regulation of trypanothione formation Any process that activates or increases the frequency, rate or extent of trypanothione biosynthetic process. GO:2000783 negative regulation of establishment of cell polarity regulating cell shape biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000783 Any process that stops, prevents or reduces the frequency, rate or extent of establishment of cell polarity regulating cell shape. GO:0016940 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016940 GO:0016941 natriuretic peptide receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016941 Combining with a natriuretic peptide and transmitting the signal to initiate a change in cell activity. GO:1905725 protein localization to microtubule end biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905725 protein localisation to microtubule end A process in which a protein is transported to, or maintained in, a location at a microtubule end. GO:2000784 positive regulation of establishment of cell polarity regulating cell shape biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000784 Any process that activates or increases the frequency, rate or extent of establishment of cell polarity regulating cell shape. GO:2000785 regulation of autophagosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000785 regulation of PAS formation|regulation of autophagosome formation|regulation of autophagic vacuole formation|regulation of autophagosome biosynthesis|regulation of autophagic vacuole assembly Any process that modulates the frequency, rate or extent of autophagosome assembly. GO:0016942 insulin-like growth factor binding protein complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0016942 IGF binding protein complex A complex of proteins which includes the insulin-like growth factor (IGF) and a number of IGF-binding proteins. The complex plays a role in growth and development. CHEBI:16498 N-acylneuraminic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16498 CHEBI:90477 3-(beta-D-galactosyl)-1,2-bis(long-chain acyl)-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90477 CHEBI:16496 5beta-cholestane-3alpha,7alpha,12alpha-triol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16496 CHEBI:16497 dGTP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16497 GO:0002306 CD4-positive gamma-delta intraepithelial T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002306 CD4-positive, gamma-delta intraepithelial T cell development|CD4-positive, gamma-delta intraepithelial T lymphocyte differentiation|CD4-positive, gamma-delta intraepithelial T-cell differentiation|CD4-positive, gamma-delta intraepithelial T-lymphocyte differentiation The process in which a precursor cell type acquires the specialized features of a CD4-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways. CHEBI:16494 lipoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16494 CHEBI:16495 4alpha-methyllathosterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16495 GO:0002307 CD8-positive, alpha-beta regulatory T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002307 CD8-positive, alpha-beta regulatory T-cell differentiation|CD8-positive, alpha-beta regulatory T-lymphocyte differentiation|CD8-positive, alpha-beta regulatory T cell development|CD8-positive, alpha-beta regulatory T lymphocyte differentiation The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta regulatory T cell. GO:0051310 metaphase plate congression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051310 chromosome congression The alignment of chromosomes at the metaphase plate (spindle equator), a plane halfway between the poles of the spindle. CHEBI:16492 nucleoside 3'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16492 GO:0002308 CD8-positive, alpha-beta cytotoxic T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002308 CD8-positive, alpha-beta cytotoxic T-lymphocyte differentiation|CD8-positive, alpha-beta cytotoxic T cell development|CD8-positive, alpha-beta cytotoxic T lymphocyte differentiation|CD8-positive, alpha-beta cytotoxic T-cell differentiation The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta cytotoxic T cell. GO:0002309 T cell proliferation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002309 T-cell proliferation during immune response|T cell proliferation during immune response|T lymphocyte proliferation during immune response|T-lymphocyte proliferation during immune response The expansion of a T cell population by cell division as part of an immune response. CHEBI:90475 3-(beta-D-galactosyl)-2-mono(long-chain acyl)-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90475 CHEBI:16493 1-deoxy-D-xylulose 5-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16493 CHEBI:16490 S-adenosyl-4-methylthio-2-oxobutanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16490 GO:0051324 prophase biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0051324 Wikipedia:Prophase The cell cycle phase which is the first stage of M phase of meiosis and mitosis and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell. GO:0002313 mature B cell differentiation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002313 mature B cell development involved in immune response|mature B-lymphocyte differentiation during immune response|mature B-cell differentiation during immune response|mature B cell differentiation during immune response|mature B lymphocyte differentiation during immune response The process in which a naive B cell acquires the specialized features of a mature or memory B cell during an immune response. GO:0051325 interphase biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0051325 Wikipedia:Interphase karyostasis|resting phase The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when prophase of meiosis or mitosis begins. During interphase the cell readies itself for meiosis or mitosis and the replication of its DNA occurs. GO:0002314 germinal center B cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002314 germinal center B cell development|germinal center B lymphocyte differentiation|germinal center B-cell differentiation|germinal center B-lymphocyte differentiation The process in which a B cell in the spleen acquires the specialized features of a germinal center B cell. Germinal center B cells are rapidly cycling B cells which have downregulated IgD expression and exhibit high levels of binding by peanut agglutinin (PNA). GO:0002315 marginal zone B cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002315 marginal zone B-cell differentiation|marginal zone B-lymphocyte differentiation|marginal zone B cell development|marginal zone B lymphocyte differentiation The process in which a B cell in the spleen acquires the specialized features of a marginal zone B cell. Marginal zone B cells are localized in a distinct anatomical region of the spleen that represents the major antigen-filtering and scavenging area (by specialized macrophages resident there). It appears that they are preselected to express a BCR repertoire similar to B-1 B cells, biased toward bacterial cell wall constituents and senescent self-components (such as oxidized LDL). GO:0051322 anaphase biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0051322 Wikipedia:Anaphase The cell cycle phase, following metaphase, during which the chromosomes separate and migrate towards the poles of the spindle. GO:0051323 metaphase biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0051323 Wikipedia:Metaphase The cell cycle phase, following prophase or prometaphase in higher eukaryotes, during which chromosomes become aligned on the equatorial plate of the cell. GO:0002316 follicular B cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002316 follicular B cell development|follicular B lymphocyte differentiation|follicular B-cell differentiation|follicular B-lymphocyte differentiation The process in which a B cell in the spleen acquires the specialized features of a follicular B cell. Follicular B cells are major population of mature recirculating B cells in the spleen and are located in the B-cell follicle region. GO:0051328 meiotic interphase biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0051328 interphase of meiotic cell cycle The cell cycle phase which begins after cytokinesis and ends when meiotic prophase begins. Meiotic cells have an interphase after each meiotic division, but only interphase I involves replication of the cell's DNA. GO:0051329 mitotic interphase biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0051329 interphase of mitotic cell cycle The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when mitotic prophase begins. During interphase the cell readies itself for mitosis and the replication of its DNA occurs. GO:0002310 alpha-beta T cell proliferation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002310 alpha-beta T-lymphocyte proliferation during immune response|alpha-beta T-cell proliferation during immune response|alpha-beta T cell proliferation during immune response|alpha-beta T lymphocyte proliferation during immune response The expansion of an alpha-beta T cell population by cell division as part of an immune response. GO:0051326 telophase biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0051326 Wikipedia:Telophase The cell cycle phase which follows anaphase during M phase of mitosis and meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts. GO:0002311 gamma-delta T cell proliferation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002311 gamma-delta T cell proliferation during immune response|gamma-delta T lymphocyte proliferation during immune response|gamma-delta T-lymphocyte proliferation during immune response|gamma-delta T-cell proliferation during immune response The expansion of a gamma-delta T cell population by cell division as part of an immune response. GO:0002312 B cell activation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002312 B lymphocyte activation during immune response|B-cell activation during immune response|B-lymphocyte activation during immune response|B cell activation during immune response The change in morphology and behavior of a mature or immature B cell during an immune response, resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. GO:0051327 meiotic M phase biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0051327 M phase of meiotic cell cycle A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a meiotic cell cycle. GO:2000797 regulation of amniotic stem cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000797 Any process that modulates the frequency, rate or extent of amniotic stem cell differentiation. GO:2000798 negative regulation of amniotic stem cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000798 Any process that stops, prevents or reduces the frequency, rate or extent of amniotic stem cell differentiation. GO:2000799 positive regulation of amniotic stem cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000799 Any process that activates or increases the frequency, rate or extent of amniotic stem cell differentiation. GO:0016958 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016958 CHEBI:41450 gamma-carboxy-L-glutamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_41450 GO:0016959 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016959 GO:0016954 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016954 GO:2000790 regulation of mesenchymal cell proliferation involved in lung development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000790 Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation involved in lung development. GO:0016955 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016955 GO:2000791 negative regulation of mesenchymal cell proliferation involved in lung development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000791 Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell proliferation involved in lung development. GO:0016956 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016956 GO:2000792 positive regulation of mesenchymal cell proliferation involved in lung development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000792 Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in lung development. GO:0016957 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016957 GO:0016950 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016950 GO:2000793 cell proliferation involved in heart valve development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000793 cell proliferation of heart valve development|cell proliferation of cardiac valve development Any cell proliferation that is involved in heart valve development. CHEBI:90469 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-2-mono(long-chain acyl)-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90469 GO:1905735 regulation of L-proline import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905735 Any process that modulates the frequency, rate or extent of L-proline import across plasma membrane. GO:2000794 regulation of epithelial cell proliferation involved in lung morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000794 Any process that modulates the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis. GO:0016951 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016951 GO:1905736 negative regulation of L-proline import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905736 Any process that stops, prevents or reduces the frequency, rate or extent of L-proline import across plasma membrane. CHEBI:16489 lumazine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16489 GO:0016952 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016952 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000795 Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis. GO:2000796 Notch signaling pathway involved in negative regulation of venous endothelial cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000796 Notch-receptor signaling pathway involved in negative regulation of venous endothelial cell fate commitment|Notch-receptor signalling pathway involved in negative regulation of venous endothelial cell fate commitment|Notch receptor signalling pathway involved in negative regulation of venous endothelial cell fate commitment|Notch receptor signaling pathway involved in negative regulation of venous endothelial cell fate commitment|Notch signalling pathway involved in negative regulation of venous endothelial cell fate commitment|N signaling pathway involved in negative regulation of venous endothelial cell fate commitment Any Notch signaling pathway that is involved in negative regulation of venous endothelial cell fate commitment. GO:1905737 positive regulation of L-proline import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905737 Any process that activates or increases the frequency, rate or extent of L-proline import across plasma membrane. GO:0016953 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016953 CHEBI:16487 benzyl cetraxate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16487 CHEBI:16488 meso-2,6-diaminopimelic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16488 CHEBI:16485 18-hydroxycorticosterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16485 CHEBI:16486 cyclopentanone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16486 GO:0051320 S phase biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0051320 Wikipedia:S_phase S-phase The cell cycle phase, following G1, during which DNA synthesis takes place. CHEBI:16483 isonocardicin A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16483 GO:0002317 plasma cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002317 plasma cell development The process in which a B cell acquires the specialized features of a plasma cell. A plasma cell is a lymphocyte which develops from a B cell and produces high amounts of antibody. GO:0051321 meiotic cell cycle biolink:BiologicalProcess go-plus goslim_drosophila|goslim_yeast http://purl.obolibrary.org/obo/GO_0051321 Wikipedia:Meiosis meiosis Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions. GO:0002318 myeloid progenitor cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002318 The process in which a precursor cell type acquires the specialized features of a myeloid progenitor cell. Myeloid progenitor cells include progenitor cells for any of the myeloid lineages. GO:0002319 memory B cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002319 memory B lymphocyte differentiation|memory B-cell differentiation|memory B-lymphocyte differentiation|memory B cell development The process in which a B cell acquires the specialized features of a memory B cell. Memory B cells are cells that can respond rapidly to antigen re-exposure by production of high-affinity antibody. CHEBI:16481 N-(hydroxymethyl)urea biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16481 CHEBI:90463 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-1,2-bis(long-chain acyl)-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90463 CHEBI:16482 naphthalene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16482 GO:0075302 regulation of basidiospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075302 Any process that modulates the frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi Basidiomycetes. GO:0051335 meiosis II nuclear envelope reassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051335 The reformation of the nuclear envelope during meiosis II. GO:0051336 regulation of hydrolase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051336 hydrolase regulator Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3. GO:0075303 positive regulation of basidiospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075303 Any process that activates, maintains or increases the frequency, rate or extent of frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi basidiomycetes. GO:0075304 negative regulation of basidiospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075304 Any process that stops, prevents, or reduces the frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi basidiomycetes. GO:0051333 meiotic nuclear envelope reassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051333 The cell cycle process in which the reformation of the nuclear envelope during meiosis occurs. GO:0075305 obsolete modulation of growth or development of symbiont on or near host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075305 modulation of growth or development of symbiont on or near host|modulation of growth or development of symbiont on or near host surface OBSOLETE. Any process by which the symbiont regulates the increase in its size or mass, or its progression from an initial condition to a later condition, on or near the cells or tissues of the host organism. GO:0051334 meiosis I nuclear envelope reassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051334 The reformation of the nuclear envelope during meiosis I. CHEBI:90493 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-2-octoanoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90493 GO:0075306 regulation of conidium formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075306 Any process that modulates the frequency, rate or extent of conidium formation, a process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus. GO:0051339 regulation of lyase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051339 lyase regulator Any process that modulates the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring. GO:0075307 positive regulation of conidium formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075307 Any process that activates, maintains or increases the frequency, rate or extent of conidium formation, a process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus. GO:0051337 amitosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051337 direct nuclear division|Remak nuclear division Nuclear division that occurs by simple constriction of the nucleus without chromosome condensation or spindle formation. GO:0075308 negative regulation of conidium formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075308 Any process that stops, prevents, or reduces the frequency, rate or extent of conidium formation, a process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus. GO:0075309 obsolete negative regulation of growth or development of symbiont on or near host surface biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075309 negative regulation of growth or development of symbiont on or near host surface OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the increase in the symbiont's size or mass, or its progression from an initial condition to a later condition, on or near the cells or tissues of the host organism. GO:0051338 regulation of transferase activity biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0051338 transferase regulator Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. GO:0016929 SUMO-specific protease activity biolink:MolecularActivity go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0016929 SUSP|ULP Catalysis of the hydrolysis of peptide or isopeptide bonds within SUMO, or between the SUMO and a larger protein to which it has been conjugated. GO:0016925 protein sumoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016925 Wikipedia:SUMO_protein small ubiquitin-related protein 1 conjugation|sumoylation|SUMO-protein conjugation|protein sumolation The process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein. GO:0016926 protein desumoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016926 desumoylation|protein desumolation The process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein. GO:0016927 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016927 GO:1905750 negative regulation of endosome to plasma membrane protein transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905750 downregulation of endosome to plasma membrane protein transport|down-regulation of endosome to plasma membrane protein transport|inhibition of endosome to plasma membrane protein transport|down regulation of endosome to plasma membrane protein transport Any process that stops, prevents or reduces the frequency, rate or extent of endosome to plasma membrane protein transport. GO:1905751 positive regulation of endosome to plasma membrane protein transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905751 up regulation of endosome to plasma membrane protein transport|activation of endosome to plasma membrane protein transport|up-regulation of endosome to plasma membrane protein transport|upregulation of endosome to plasma membrane protein transport Any process that activates or increases the frequency, rate or extent of endosome to plasma membrane protein transport. GO:0016928 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016928 GO:1905741 calcium export from the mitochondrion involved in positive regulation of presynaptic cytosolic calcium concentration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905741 calcium ion transmembrane export from mitochondrion involved in positive regulation of presynaptic cytosolic calcium concentration|mitochondrial calcium release involved in positive regulation of presynaptic cytosolic calcium concentration Any mitochondrial calcium release that is involved in positive regulation of presynaptic cytosolic calcium concentration. GO:0016921 obsolete pyroglutamyl-peptidase II activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016921 EC:3.4.19.6|MetaCyc:3.4.19.6-RXN pyroglutamyl peptidase II|thyroliberin-hydrolyzing pyroglutamate aminopeptidase activity|TRH-DE activity|thyrotropin-releasing hormone degrading ectoenzyme activity|TRH-degrading ectoenzyme activity|thyrotropin-releasing hormone-degrading pyroglutamate aminopeptidase activity|TRH-specific aminopeptidase activity|thyrotropin-releasing hormone-degrading peptidase activity|pyroglutamyl aminopeptidase II activity|PAP-II activity|pyroglutamyl-peptidase II activity|thyrotropin-releasing factor pyroglutamate aminopeptidase activity|thyroliberinase activity|pyroglutamate aminopeptidase II OBSOLETE. Catalysis of the release of the N-terminal pyroglutamyl group from pGlu-His-Xaa tripeptides and pGlu-His-Xaa-Gly tetrapeptides. GO:1905742 Ras guanyl-nucleotide exchange factor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1905742 A protein complex which is capable of Ras guanyl-nucleotide exchange factor activity. GO:0016922 nuclear receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016922 ligand-dependent nuclear receptor binding|ligand-dependent nuclear receptor interactor activity Interacting selectively and non-covalently, in a ligand dependent manner, with a nuclear receptor protein. GO:0016923 obsolete ligand-dependent thyroid hormone receptor interactor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016923 ligand-dependent thyroid hormone receptor interactor activity|TRIP4 OBSOLETE. Ligand dependent interaction with the thyroid hormone receptor. GO:1905743 calcium import into the mitochondrion involved in negative regulation of presynaptic cytosolic calcium concentration biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_1905743 calcium ion transmembrane import into mitochondrion involved in negative regulation of presynaptic cytosolic calcium concentration|mitochondrial calcium uptake involved in negative regulation of presynaptic cytosolic calcium concentration Any mitochondrial calcium uptake that is involved in negative regulation of presynaptic cytosolic calcium concentration. GO:0016924 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016924 GO:1905744 regulation of mRNA cis splicing, via spliceosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905744 regulation of nuclear mRNA cis splicing, via U2-type spliceosome|regulation of splicing|regulation of nuclear mRNA cis splicing, via spliceosome Any process that modulates the frequency, rate or extent of mRNA cis splicing, via spliceosome. GO:1905745 negative regulation of mRNA cis splicing, via spliceosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905745 Any process that stops, prevents or reduces the frequency, rate or extent of mRNA cis splicing, via spliceosome. GO:1905746 positive regulation of mRNA cis splicing, via spliceosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905746 Any process that activates or increases the frequency, rate or extent of mRNA cis splicing, via spliceosome. GO:1905747 negative regulation of saliva secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905747 down-regulation of saliva secretion|negative regulation of salivation|down-regulation of salivation|downregulation of saliva secretion|downregulation of salivation|down regulation of saliva secretion|inhibition of saliva secretion|down regulation of salivation|inhibition of salivation Any process that stops, prevents or reduces the frequency, rate or extent of saliva secretion. GO:1905748 hard palate morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905748 palatum durum morphogenesis The developmental process by which a hard palate is generated and organized. GO:0016920 pyroglutamyl-peptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016920 EC:3.4.19.- Catalysis of the release of the N-terminal pyroglutamyl group from a peptide or protein. GO:1905749 regulation of endosome to plasma membrane protein transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905749 Any process that modulates the frequency, rate or extent of endosome to plasma membrane protein transport. CHEBI:90499 (7Z,10Z,13Z)-hexadecatrienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90499 GO:0051331 meiotic G2 phase biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0051331 G2 phase of meiotic cell cycle The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation by meiosis. GO:0051332 meiotic S phase biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0051332 S phase of meiotic cell cycle|S-phase of meiotic cell cycle The cell cycle phase, following G1, during which DNA synthesis takes place as part of a meiotic cell cycle. GO:0075300 negative regulation of zygospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075300 Any process that stops, prevents, or reduces the frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase. GO:0075301 obsolete cell differentiation involved in spore germination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0075301 OBSOLETE. The process in which a relatively unspecialized cell acquires specialized features of a specific cell type occurring during spore germination, the physiological and developmental changes that occur in a spore following release from dormancy up to the earliest signs of growth. GO:0051330 meiotic G1 phase biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0051330 G1 phase of meiotic cell cycle The cell cycle 'gap' phase which is the interval between the completion of DNA segregation by meiosis and the beginning of DNA synthesis. GO:0051346 negative regulation of hydrolase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051346 down regulation of hydrolase activity|inhibition of hydrolase activity|hydrolase inhibitor|down-regulation of hydrolase activity|downregulation of hydrolase activity Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds. GO:0051347 positive regulation of transferase activity biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0051347 up-regulation of transferase activity|activation of transferase activity|up regulation of transferase activity|transferase activator|upregulation of transferase activity|stimulation of transferase activity Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor. GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051344 3',5' cyclic nucleotide phosphodiesterase inhibitor|down regulation of cyclic nucleotide phosphodiesterase activity|inhibition of cyclic nucleotide phosphodiesterase activity|phosphodiesterase inhibitor|negative regulation of 3',5'-cyclic-AMP phosphodiesterase activity|3',5'-cyclic-AMP phosphodiesterase inhibitor|negative regulation of cyclic nucleotide phosphodiesterase activity|down-regulation of cyclic nucleotide phosphodiesterase activity|negative regulation of cAMP phosphodiesterase activity|negative regulation of cGMP phosphodiesterase activity|cAMP phosphodiesterase inhibitor|downregulation of cyclic nucleotide phosphodiesterase activity|negative regulation of 3',5' cyclic nucleotide phosphodiesterase activity Any process that stops or reduces the rate of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate. CHEBI:90481 2-octanoyl-3-(beta-D-galactosyl)-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90481 GO:0051345 positive regulation of hydrolase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051345 upregulation of hydrolase activity|stimulation of hydrolase activity|up-regulation of hydrolase activity|activation of hydrolase activity|up regulation of hydrolase activity|hydrolase activator Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds. GO:0051348 negative regulation of transferase activity biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0051348 down-regulation of transferase activity|downregulation of transferase activity|down regulation of transferase activity|inhibition of transferase activity|transferase inhibitor Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor. UBERON:6001728 larval tagma biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_6001728 Any tagma (UBERON:6000002) that is part of some larva (UBERON:6001727). GO:0051349 positive regulation of lyase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051349 up regulation of lyase activity|lyase activator|upregulation of lyase activity|stimulation of lyase activity|activation of lyase activity|up-regulation of lyase activity Any process that activates or increases the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. UBERON:6001729 larval segment biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_6001729 Any segment that is part of some larva. GO:0016936 galactoside binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0016936 Interacting selectively and non-covalently with any glycoside in which the sugar group is galactose. GO:1905760 post-anaphase array microtubule end biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1905760 microtubule end of microtubule of PAA|microtubule end of post-anaphase array microtubule|microtubule end of microtubule of post-anaphase array|microtubule end of neurotubule of post-anaphase microtubule array|microtubule end of microtubuli of PAA|microtubule end of microtubuli of post-anaphase array|microtubule end of microtubulus of PAA|microtubule end of microtubulus of post-anaphase array|microtubule end of neurotubule of PAA|microtubule end of microtubule of post-anaphase microtubule array|microtubule end of neurotubule of post-anaphase array|microtubule end of microtubuli of post-anaphase microtubule array|microtubule end of microtubulus of post-anaphase microtubule array Any microtubule end that is part of a post-anaphase array microtubule. GO:0016937 short-branched-chain-acyl-CoA dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016937 EC:1.3.99.- Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor, where the acyl group is a short branched chain fatty acid residue. GO:1905761 SCF ubiquitin ligase complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1905761 SCF complex substrate recognition subunit binding|SCF complex binding|CRL1 complex binding|Cul1-RING ubiquitin ligase complex binding|CDL1 complex binding|Skp1/Cul1/F-box protein complex binding|cullin-RING ligase 1 binding Interacting selectively and non-covalently with a SCF ubiquitin ligase complex. GO:0016938 kinesin I complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016938 A complex of two kinesin heavy chains and two kinesin light chains. GO:1905762 CCR4-NOT complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1905762 Interacting selectively and non-covalently with a CCR4-NOT complex. GO:0016939 kinesin II complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016939 A complex consisting of two distinct motor subunits that form a heterodimer complexed with a third non-motor accessory subunit, the kinesin associated protein or KAP; the KIF3 heterodimer interacts via its C-terminal portion with KAP, which is thought to regulate the binding of the motor to cargo membranes. GO:1905752 regulation of argininosuccinate synthase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905752 regulation of citrulline--aspartate ligase activity|regulation of L-citrulline:L-aspartate ligase (AMP-forming)|regulation of argininosuccinate synthetase activity|regulation of arginosuccinate synthetase activity|regulation of arginine succinate synthetase activity|regulation of argininosuccinic acid synthetase activity Any process that modulates the frequency, rate or extent of argininosuccinate synthase activity. GO:0016932 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016932 GO:1905753 positive regulation of argininosuccinate synthase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905753 up-regulation of citrulline--aspartate ligase activity|up-regulation of L-citrulline:L-aspartate ligase (AMP-forming)|up-regulation of argininosuccinate synthetase activity|up-regulation of arginine succinate synthetase activity|up regulation of argininosuccinate synthase activity|up regulation of argininosuccinic acid synthetase activity|activation of arginine succinate synthetase activity|positive regulation of argininosuccinic acid synthetase activity|activation of argininosuccinic acid synthetase activity|activation of argininosuccinate synthase activity|up-regulation of arginosuccinate synthetase activity|upregulation of citrulline--aspartate ligase activity|upregulation of argininosuccinate synthetase activity|upregulation of L-citrulline:L-aspartate ligase (AMP-forming)|positive regulation of arginine succinate synthetase activity|upregulation of arginosuccinate synthetase activity|up regulation of arginine succinate synthetase activity|up-regulation of argininosuccinic acid synthetase activity|up-regulation of argininosuccinate synthase activity|up regulation of citrulline--aspartate ligase activity|up regulation of argininosuccinate synthetase activity|up regulation of L-citrulline:L-aspartate ligase (AMP-forming)|activation of citrulline--aspartate ligase activity|positive regulation of citrulline--aspartate ligase activity|positive regulation of argininosuccinate synthetase activity|activation of L-citrulline:L-aspartate ligase (AMP-forming)|activation of argininosuccinate synthetase activity|positive regulation of L-citrulline:L-aspartate ligase (AMP-forming)|upregulation of argininosuccinate synthase activity|upregulation of argininosuccinic acid synthetase activity|up regulation of arginosuccinate synthetase activity|upregulation of arginine succinate synthetase activity|activation of arginosuccinate synthetase activity|positive regulation of arginosuccinate synthetase activity Any process that activates or increases the frequency, rate or extent of argininosuccinate synthase activity. GO:0016933 extracellularly glycine-gated ion channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016933 glycine receptor|extracellular-glycine-gated ion channel activity Enables the transmembrane transfer of an ion by a channel that opens when glycine is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane. GO:0016934 extracellularly glycine-gated chloride channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016934 Reactome:R-HSA-975389 glycine-inhibited chloride channel activity|glycine receptor|extracellular-glycine-gated chloride channel activity Enables the transmembrane transfer of a chloride ion by a channel that opens when glycine is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane. GO:1905754 ascospore-type prospore nucleus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1905754 nucleus of ascospore-type prospore|cell nucleus of ascospore-type prospore Any nucleus that is part of a ascospore-type prospore. GO:0016935 glycine-gated chloride channel complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016935 A protein complex that forms a transmembrane channel through which chloride ions may pass in response to glycine binding to the channel complex or one of its constituent parts. GO:1905755 protein localization to cytoplasmic microtubule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905755 protein localisation to cytoplasmic microtubule A process in which a protein is transported to, or maintained in, a location within a cytoplasmic microtubule. GO:1905756 regulation of primary cell septum biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905756 Any process that modulates the frequency, rate or extent of primary cell septum biogenesis. GO:1905757 negative regulation of primary cell septum biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905757 Any process that stops, prevents or reduces the frequency, rate or extent of primary cell septum biogenesis. GO:1905758 positive regulation of primary cell septum biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905758 Any process that activates or increases the frequency, rate or extent of primary cell septum biogenesis. GO:0016930 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016930 GO:1905759 post-anaphase array microtubule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1905759 neurotubule of post-anaphase array|microtubuli of post-anaphase microtubule array|microtubule of PAA|microtubulus of PAA|microtubule of post-anaphase array|neurotubule of post-anaphase microtubule array|microtubuli of PAA|microtubulus of post-anaphase array|microtubuli of post-anaphase array|neurotubule of PAA|microtubule of post-anaphase microtubule array|microtubulus of post-anaphase microtubule array Any microtubule that is part of a post-anaphase microtubule array. GO:0016931 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016931 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051342 cAMP phosphodiesterase regulator|3',5' cyclic nucleotide phosphodiesterase regulator|regulation of cAMP phosphodiesterase activity|regulation of 3',5' cyclic nucleotide phosphodiesterase activity|regulation of cGMP phosphodiesterase activity|phosphodiesterase regulator|3',5'-cyclic-AMP phosphodiesterase regulator|regulation of cyclic nucleotide phosphodiesterase activity|regulation of 3',5'-cyclic-AMP phosphodiesterase activity Any process that modulates the frequency, rate or extent of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate. GO:0051343 positive regulation of cyclic-nucleotide phosphodiesterase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051343 positive regulation of 3',5' cyclic nucleotide phosphodiesterase activity|positive regulation of 3',5'-cyclic-AMP phosphodiesterase activity|upregulation of cyclic nucleotide phosphodiesterase activity|stimulation of cyclic nucleotide phosphodiesterase activity|up-regulation of cyclic nucleotide phosphodiesterase activity|activation of cyclic nucleotide phosphodiesterase activity|cAMP phosphodiesterase activator|positive regulation of cAMP phosphodiesterase activity|positive regulation of cGMP phosphodiesterase activity|positive regulation of cyclic nucleotide phosphodiesterase activity|3',5' cyclic nucleotide phosphodiesterase activator|phosphodiesterase activator|up regulation of cyclic nucleotide phosphodiesterase activity|3',5'-cyclic-AMP phosphodiesterase activator Any process that activates or increases the frequency, rate or extent of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate. GO:0051340 regulation of ligase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051340 ligase regulator Any process that modulates the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate. Ligase is the systematic name for any enzyme of EC class 6. GO:0051341 regulation of oxidoreductase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051341 oxidoreductase regulator Any process that modulates the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. CHEBI:145037 hydroperoxy fatty ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145037 CHEBI:145026 L-psicose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_145026 GO:0002386 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0002386 GO:0002387 immune response in gut-associated lymphoid tissue biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002387 immune response in GALT Immune response taking place in the gut-associated lymphoid tissue (GALT). GALT includes Peyer's patches, appendix, and solitary lymph nodules. GO:0002388 immune response in Peyer's patch biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002388 Immune response taking place in the Peyer's patch, nodular lymphoid structures on the serosal surface of the small intestine. GO:0002389 tolerance induction in Peyer's patch biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002389 Tolerance induction taking place in the Peyer's patches. GO:0002382 regulation of tissue kallikrein-kinin cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002382 regulation of glandular kallikrein-kinin cascade Any process that modulates the frequency, rate, or extent of the tissue kallikrein-kinin cascade. GO:0002383 immune response in brain or nervous system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002383 An immune response taking place in the brain or nervous system. GO:0002384 hepatic immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002384 An immune response taking place in the liver. GO:0002385 mucosal immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002385 immune response in MALT|immune response in mucosal-associated lymphoid tissue|immune response in urogenital tract An immune response taking place in mucosal tissues, including those of the intestinal tract, nasal and upper respiratory tract, and genital tract. GO:0002380 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0002380 GO:0002381 immunoglobulin production involved in immunoglobulin-mediated immune response biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0002381 immunoglobulin production involved in immunoglobulin mediated immune response|antibody secretion during immune response|immunoglobulin secretion involved in immune response|immunoglobulin production during immune response|immunoglobulin biosynthetic process involved in immune response|antibody production during immune response|immunoglobulin production involved in immune response The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels. GO:0002397 MHC class I protein complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002397 The aggregation, arrangement and bonding together of a set of components to form an MHC class I protein complex. Class I here refers to classical class I molecules. GO:0002398 MHC class Ib protein complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002398 The aggregation, arrangement and bonding together of a set of components to form an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules. GO:0002399 MHC class II protein complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002399 The aggregation, arrangement and bonding together of a set of components to form an MHC class II protein complex. GO:0002393 lysosomal enzyme production involved in inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002393 production of lysosomal enzymes involved in acute inflammatory response|production of lysosomal enzymes involved in inflammatory response|lysosomal enzyme production involved in acute inflammatory response The synthesis or release of lysosomal enzymes following a stimulus as part of a inflammatory response, resulting in an increase in intracellular or extracellular levels. GO:0002394 tolerance induction in gut-associated lymphoid tissue biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002394 tolerance induction in GALT|oral tolerance Tolerance induction taking place in the gut-associated lymphoid tissue (GALT). GO:0002395 immune response in nasopharyngeal-associated lymphoid tissue biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002395 immune response in NALT An immune response taking place in the nasopharyngeal-associated lymphoid tissue (NALT). NALT includes the tonsils and adenoids. GO:0002396 MHC protein complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002396 The aggregation, arrangement and bonding together of a set of components to form an MHC protein complex. GO:0002390 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0002390 GO:0002391 platelet activating factor production involved in inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002391 platelet activating factor production|platelet activating factor production involved in acute inflammatory response|platelet activating factor secretion|platelet activating factor secretion involved in acute inflammatory response|platelet activating factor secretion involved in inflammatory response The synthesis or release of platelet activating factor following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. GO:0002392 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0002392 PR:000003652 acrosin biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000003652 ACRS|ACR A protein that is a translation product of the human ACR gene or a 1:1 ortholog thereof. GO:0002368 B cell cytokine production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0002368 B-cell cytokine production|B-lymphocyte cytokine production|B lymphocyte cytokine production Any process that contributes to cytokine production by a B cell. GO:0002369 T cell cytokine production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0002369 T lymphocyte cytokine production|T-cell cytokine production|T-lymphocyte cytokine production Any process that contributes to cytokine production by a T cell. GO:0002364 NK T cell lineage commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002364 natural killer T lymphocyte lineage commitment|NK T lymphocyte lineage commitment|natural killer T-lymphocyte lineage commitment|natural killer T-cell lineage commitment|NK T-lymphocyte lineage commitment|NK T-cell lineage commitment The process in which a pro-T cell becomes committed to becoming an NK T cell. GO:0002365 gamma-delta T cell lineage commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002365 gamma-delta T-lymphocyte lineage commitment|gamma-delta T-cell lineage commitment|gamma-delta T lymphocyte lineage commitment The process in which a pro-T cell becomes committed to becoming a gamma-delta T cell. GO:0002366 leukocyte activation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002366 immune cell activation during immune response|leucocyte activation during immune response|leukocyte activation during immune response A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. GO:0002367 cytokine production involved in immune response biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0002367 cytokine biosynthetic process involved in immune response|cytokine production during immune response|cytokine secretion involved in immune response|cytokine secretion during immune response The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus contributing to an immune response, resulting in an increase in its intracellular or extracellular levels. GO:0002360 T cell lineage commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002360 T lymphocyte lineage commitment|T-lymphocyte lineage commitment|T-cell lineage commitment The process in which a lymphoid progenitor cell becomes committed to becoming any type of T cell. GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002361 CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation|CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation|CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation|CD4-positive, CD25-positive, alpha-beta regulatory T cell development The process in which a precursor cell type acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell. GO:0002362 CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002362 CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte lineage commitment|CD4-positive, CD25-positive, alpha-beta regulatory T-cell lineage commitment|CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte lineage commitment The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a CD4-positive, CD25-positive, alpha-beta regulatory T cell. GO:0002363 alpha-beta T cell lineage commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002363 alpha-beta T lymphocyte lineage commitment|alpha-beta T-lymphocyte lineage commitment|alpha-beta T-cell lineage commitment The process in which a pro-T cell becomes committed to becoming an alpha-beta T cell. CHEBI:90418 N(6)-D-ribulosyl-L-lysinium residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90418 GO:0002379 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0002379 GO:0002375 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0002375 GO:0002376 immune system process biolink:BiologicalProcess go-plus goslim_flybase_ribbon|goslim_chembl|goslim_mouse|goslim_agr|goslim_pir|goslim_generic http://purl.obolibrary.org/obo/GO_0002376 Wikipedia:Immune_system Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats. GO:0002377 immunoglobulin production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0002377 antibody production|immunoglobulin biosynthetic process|immunoglobulin secretion The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0002378 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0002378 GO:0002371 dendritic cell cytokine production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0002371 Any process that contributes to cytokine production by a dendritic cell. GO:0002372 myeloid dendritic cell cytokine production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0002372 Any process that contributes to cytokine production by a myeloid dendritic cell. GO:0002373 plasmacytoid dendritic cell cytokine production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0002373 Any process that contributes to cytokine production by a plasmacytoid dendritic cell. GO:0002374 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0002374 GO:0002370 natural killer cell cytokine production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0002370 NK cell cytokine production Any process that contributes to cytokine production by a natural killer cell. CHEBI:90409 5-hydroxymethyluridine-2'-deoxy-5'-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90409 CHEBI:89417 5alpha-dihydrotestosterone 17-O-(beta-D-glucuronide) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_89417 CHEBI:90400 alpha-D-GalNAc-(1->3)-beta-D-GalNAc-(1->3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90400 GO:0110137 regulation of imaginal disc-derived leg joint morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110137 Any process that modulates the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis, the process in which the anatomical structure of the imaginal disc-derived leg joint is generated and organized. GO:0110138 positive regulation of imaginal disc-derived leg joint morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110138 Any process that activates or increases the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis. GO:0110135 Norrin signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110135 The series of molecular signals initiated by binding of the cysteine knot protein Norrin to a Frizzled 4 (Fzd4) family receptor on the surface of the target cell and ending with a change in cell state. GO:0110136 protein-RNA complex remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110136 The acquisition, loss, or modification of macromolecules within a protein-RNA complex, resulting in the alteration of an existing complex. GO:0110133 negative regulation of CRISPR-cas system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110133 Any process that stops, prevents, or reduces the frequency, rate or extent of a CRISPR-cas system. GO:0110134 meiotic drive biolink:BiologicalProcess go-plus goslim_pombe http://purl.obolibrary.org/obo/GO_0110134 A biological process that results in the unequal transmission of alleles, haplotypes, or chromosomes from a parental genome to gametes. In the absence of meiotic drive, the two copies of each gene or chromosome in a diploid organism are transmitted to offspring with equal probability, whereas meiotic drive results in overrepresentation of the driving allele among the surviving products of meiosis. GO:0110131 Aim21-Tda2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0110131 ComplexPortal:CPX-3541 Aim21/Tda2 complex A complex that localizes to actin cortical patches at sites of endocytosis and negatively regulates barbed end F-actin assembly, resulting in the generation of free actin pools. The Aim21-Tda2 complex is necessary for efficient endocytosis and balancing the distribution of actin between patches and cables. GO:0110132 regulation of CRISPR-cas system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110132 Any process that modulates the frequency, rate or extent of a CRISPR-cas system. GO:0110130 ribitol-5-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0110130 RHEA:47648 Catalysis of the reaction: ribitol-5-phosphate + H20 = ribitol + phosphate. GO:0110139 negative regulation of imaginal disc-derived leg joint morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110139 Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis. GO:0110148 biomineralization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110148 Wikipedia:Biomineralization mineralization|biomineral formation|biomineralisation|mineralisation The process where mineral crystals are formed and deposited in an organized fashion in a matrix (either cellular or extracellular) by living organisms. This gives rise to inorganic compound-based structures such as skeleton, teeth, ivory, shells, cuticle, and corals as well as bacterial biomineralization products. GO:0110149 regulation of biomineralization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110149 regulation of biomineralisation|regulation of mineralisation|regulation of mineralization|regulation of biomineral formation Any process that modulates the frequency, rate or extent of biomineralization, the formation and deposition of mineral crystals by living organisms. GO:0110146 magnetosome membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0110146 The lipid bilayer surrounding a magnetosome. GO:0110147 protein maturation by nickel ion transfer biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110147 A process that contributes to the delivery of nickel ions to a target protein to facilitate its maturation. GO:0110144 obsolete magnetosome part biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0110144 OBSOLETE. Any constituent part of a magnetosome, a membrane-bound organelle that envelops particles of magnetic iron minerals in magnetotactic bacteria. GO:0110145 magnetosome lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0110145 The volume enclosed by the membrane of a magnetosome. GO:0110142 ubiquinone biosynthesis complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0110142 Ubi complex|CoQ metabolon The cytosolic ubiquinone biosynthesis complex is composed of enzymes and accessory factors of the ubiquinone biosynthesis pathway and enables synthesis of the extremely hydrophobic molecule ubiquinone. In E. coli, the complex is composed of seven proteins: UbiE, F, G, H, I, J and K. GO:0110143 magnetosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0110143 A membrane-bound organelle that envelops particles of magnetic iron minerals in magnetotactic bacteria. Magnetosomes form linear chains that align along the cellular motility axis at midcell and function in bacterial navigation along the Earth's magnetic field. They are formed by invagination of the cell inner membrane; in some species they remain connected to the inner membrane, in others they pinch off to form independent intracellular vesicles. GO:0110140 flagellum attachment zone organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110140 FAZ organization|flagellum attachment zone organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a flagellum attachment zone. FAZ is a network of cytoskeletal and membranous connections responsible for the lateral attachment of the cilium to the cell body in some trypanosomatid species. GO:0110141 L-glutamate import into mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110141 The process in which L-glutamate is transported from the cytosol into the mitochondrial matrix. GO:0110159 regulation of mitotic spindle formation (spindle phase one) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110159 Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one). GO:0110157 reelin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0110157 An extracellular complex that binds lipoprotein receptors VLDLR and APOER2, cadherin-related neuronal receptors (CNRs) or alpha3beta1 integrin and induces various downstream, reelin-dependent, phosphorylation cascades. It ultimately affects polarization, differentiation, neuronal migration and layer formation in the embryonic brain and neuron growth, maturation, and synaptic activity in the postnatal and adult brain. GO:0110158 calpain complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0110158 M-calpain|mu-calpain A calcium-dependent protease complex that processes its substrate by limited proteolysis rather than degrading it. In some cases limited proteolysis is required for the activation of its substrate. GO:0110155 NAD-cap decapping biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110155 Cleavage of the 5'-NAD-cap of an RNA. The NAD-cap is present at the 5'-end of some RNAs in both bacetria and eukaryotes. While it promotes RNA stability in bacteria, it promotes RNA decay in eukaryotes. GO:0110156 methylguanosine-cap decapping biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110156 Cleavage of the 5'-methylguanosine-cap of an mRNA. The methylguanosine-cap is present at the 5'-end of eukaryotic mRNAs. Decapping inactivates translation initiation and promotes 5'-to-3' decay of mRNA. UBERON:0008281 tooth bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008281 dental germ|dental bud|tooth germ A knoblike tooth primordium that develops into the mature tooth and consists of enamel organ, dental papilla, and dental sac enclosing them. GO:0110153 RNA NAD-cap (NMN-forming) hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0110153 Catalysis of the reaction: a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-adenosine-phospho-ribonucleoside in mRNA + beta-nicotinamide D-ribonucleotide + 2 H(+). GO:0110154 RNA decapping biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110154 Cleavage of the 5'-cap of an RNA. GO:0110151 positive regulation of biomineralization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110151 positive regulation of mineralisation|positive regulation of mineralization|positive regulation of biomineral formation|positive regulation of biomineralisation Any process that activates or increases the frequency, rate or extent of biomineralization, the formation and deposition of mineral crystals by living organisms. GO:0110152 RNA NAD-cap (NAD-forming) hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0110152 RHEA:60880 Catalysis of the reaction: a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + H(+) + NAD(+). GO:0110150 negative regulation of biomineralization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110150 negative regulation of mineralisation|negative regulation of mineralization|negative regulation of biomineral formation|negative regulation of biomineralisation Any process that stops, prevents, or reduces the frequency, rate or extent of biomineralization, the formation and deposition of mineral crystals by living organisms. GO:0110166 DNA synthesis involved in mitochondrial DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110166 DNA biosynthetic process involved in mitochondrial DNA replication Any DNA biosynthetic process that is involved in mitochondrial DNA replication. GO:0110164 positive regulation of mitotic spindle elongation (spindle phase three) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110164 Any process that activates or increases the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase three). GO:0110165 cellular anatomical entity biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0110165 A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex. GO:0110162 regulation of mitotic spindle elongation (spindle phase three) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110162 Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase three). GO:0110163 negative regulation of mitotic spindle elongation (spindle phase three) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110163 Any process that stops, prevents or reduces the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase three). GO:0110160 negative regulation of mitotic spindle formation (spindle phase one) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110160 Any process that stops, prevents or reduces the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one). GO:0110161 positive regulation of mitotic spindle formation (spindle phase one) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110161 Any process that activates or increases the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one). GO:0110104 mRNA alternative polyadenylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110104 The process of generating multiple mRNA molecules with variable 3'-end length formation from a given pre-mRNA by differential use of cleavage and polyadenylation signals (pA signals). GO:0110105 mRNA cleavage and polyadenylation specificity factor complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110105 The aggregation, arrangement and bonding together of a set of components to form the mRNA cleavage and polyadenylation specificity factor complex. GO:0110102 ribulose bisphosphate carboxylase complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110102 rubisco assembly|RuBisCO assembly The aggregation, arrangement and bonding together of a set of components to form a ribulose bisphosphate carboxylase complex. GO:0110103 RNA polymerase II termination complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0110103 IntAct:EBI-16426399 TXT complex A conserved protein complex capable of 5'-3' exoribonuclease activity. It is able to promote RNA polymerase II (RNAPII) transcription termination by degrading pre-mRNA from the newly formed 5' phosphorylated end. GO:0110100 spindle pole body separation biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0110100 The release of duplicated spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane. Duplicated SPBs are connected by a bridge structure that is severed in order to release the SPBs from one another. Following liberation, SPBs diffuse through the nuclear membrane until they are across from each other. SPB separation must take place in order for a bipolar spindle to assemble. GO:0110101 L-valine transmembrane import into vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110101 The directed movement of L-valine into the vacuole across the vacuolar membrane. CHEBI:145078 3-oxo aldehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_145078 GO:0110108 positive regulation of imaginal disc-derived wing vein specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110108 Any process that activates or increases the frequency, rate or extent of imaginal disc-derived wing vein specification. GO:0110109 negative regulation of imaginal disc-derived wing vein specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110109 Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc-derived wing vein specification. GO:0110107 regulation of imaginal disc-derived wing vein specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110107 Any process that modulates the frequency, rate or extent of imaginal disc-derived wing vein specification. GO:0110115 Cdr2 medial cortical node complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0110115 interphase cortical node|interphase node A megadalton-sized complex at the medial cortex organized as an oligomeric core of SAD family protein kinases involved in cell size-dependent localization and phosphorylation of Wee1 during interphase. GO:0110116 regulation of compound eye photoreceptor cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110116 Any process that modulates the frequency, rate or extent of compound eye photoreceptor cell differentiation. GO:0110113 positive regulation of lipid transporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110113 Any process that increases the frequency, rate, or extent of lipid transporter activity. GO:0110114 negative regulation of lipid transporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110114 Any process that decreases the frequency, rate, or extent of lipid transporter activity. GO:0110111 negative regulation of animal organ morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110111 Any process that stops, prevents, or reduces the frequency, rate or extent of animal organ morphogenesis. GO:0110112 regulation of lipid transporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110112 Any process that modulates the frequency, rate, or extent of lipid transporter activity. GO:0110110 positive regulation of animal organ morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110110 Any process that activates or increases the frequency, rate or extent of animal organ morphogenesis. GO:0110119 positive regulation of very-low-density lipoprotein particle clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110119 Any process that increases the frequency, rate or extent of very-low-density lipoprotein particle clearance. GO:0110117 positive regulation of compound eye photoreceptor cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110117 Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor cell differentiation. GO:0110118 negative regulation of compound eye photoreceptor cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110118 Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor cell differentiation. GO:0110126 phloem loading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110126 The process of loading solutes into the sieve tube or companion cell of the phloem for long distance transport from source to sink. GO:0110127 phloem unloading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110127 The process of unloading solutes that are produced in the source tissues, from the sieve tube or companion cell of the phloem into the sink tissues. GO:0110124 positive regulation of myotube cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110124 Any process that activates, maintains or increases the frequency, rate or extent of myotube cell migration. GO:0110125 negative regulation of myotube cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110125 Any process that stops, prevents, or reduces the frequency, rate or extent of myotube cell migration. GO:0110122 myotube cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110122 The orderly movement of a myotube cell from one site to another, often during the development of a multicellular organism. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate, and fuse. GO:0110123 regulation of myotube cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110123 Any process that modulates the frequency, rate or extent of myotube cell migration. GO:0110120 gamma-tubulin complex localization to nuclear side of mitotic spindle pole body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110120 Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location at the nuclear side of the mitotic spindle pole body. GO:0110121 gamma-tubulin complex localization to cytoplasmic side of mitotic spindle pole body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110121 Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location at the cytoplasmic side of the mitotic spindle pole body. GO:0110128 phloem sucrose unloading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0110128 The process of unloading sucrose that is produced in the source tissues, from the sieve tube or companion cell of the phloem into the sink tissues. GO:0110129 SHREC2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0110129 A histone deacetylase complex formed by the association of an HP1 protein with a SHREC complex. The SHREC2 complex is required for deacetylation of H3K14, and mediates transcriptional gene silencing by limiting RNA polymerase II access to heterochromatin. In fission yeast, the complex contains the SHREC subunits Clr1, Clr2, Clr3, and Mit1, and the HP1 protein Chp2. GO:0051478 mannosylglycerate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051478 mannosylglycerate metabolism The chemical reactions and pathways involving mannosylglycerate, a very common compatible solute in thermophilic and hyperthermophilic organisms. GO:2000629 negative regulation of miRNA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000629 negative regulation of microRNA metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of miRNA metabolic process. GO:0002500 proteolysis within lysosome associated with antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002500 lysosomal proteolysis associated with antigen processing and presentation The hydrolysis of a peptide bond or bonds within a protein by lysosomal resident proteases contributing to antigen processing and presentation. GO:0002501 peptide antigen assembly with MHC protein complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002501 The binding of a peptide to the antigen binding groove of an MHC protein complex. CHEBI:90392 alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90392 GO:0051479 mannosylglycerate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051479 mannosylglycerate anabolism|mannosylglycerate biosynthesis|mannosylglycerate synthesis|mannosylglycerate formation The chemical reactions and pathways resulting in the formation of mannosylglycerate, a very common compatible solute in thermophilic and hyperthermophilic organisms. GO:0002502 peptide antigen assembly with MHC class I protein complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002502 The binding of a peptide to the antigen binding groove of an MHC class I protein complex. Class I here refers to classical class I molecules. GO:0051476 mannosylglycerate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051476 The directed movement of mannosylglycerate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0051477 mannosylglycerate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051477 Enables the transfer of a mannosylglycerate from one side of a membrane to the other. GO:0002503 peptide antigen assembly with MHC class II protein complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002503 The binding of a peptide to the antigen binding groove of an MHC class II protein complex. IAO:0000228 term imported biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/IAO_0000228 CHEBI:90390 alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90390 IAO:0000229 term split biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/IAO_0000229 GO:2000621 regulation of DNA replication termination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000621 Any process that modulates the frequency, rate or extent of DNA replication termination. GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000622 regulation of mRNA degradation, nonsense-mediated decay|regulation of nonsense-mediated mRNA decay|regulation of mRNA catabolism, nonsense-mediated|regulation of nuclear mRNA catabolic process, nonsense-mediated decay|regulation of mRNA catabolic process, nonsense-mediated|regulation of mRNA breakdown, nonsense-mediated decay Any process that modulates the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. GO:2000623 negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000623 negative regulation of mRNA catabolism, nonsense-mediated|negative regulation of mRNA breakdown, nonsense-mediated decay|negative regulation of mRNA degradation, nonsense-mediated decay|negative regulation of nonsense-mediated mRNA decay|negative regulation of mRNA catabolic process, nonsense-mediated|negative regulation of nuclear mRNA catabolic process, nonsense-mediated decay Any process that stops, prevents or reduces the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. GO:2000624 positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000624 positive regulation of nonsense-mediated mRNA decay|positive regulation of mRNA breakdown, nonsense-mediated decay|positive regulation of mRNA catabolism, nonsense-mediated|positive regulation of mRNA degradation, nonsense-mediated decay|positive regulation of mRNA catabolic process, nonsense-mediated|positive regulation of nuclear mRNA catabolic process, nonsense-mediated decay Any process that activates or increases the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. GO:2000625 regulation of miRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000625 regulation of microRNA catabolic process Any process that modulates the frequency, rate or extent of miRNA catabolic process. GO:2000626 negative regulation of miRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000626 negative regulation of microRNA catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of miRNA catabolic process. GO:1905650 positive regulation of shell calcification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905650 up regulation of shell calcification|activation of shell calcification|up-regulation of shell calcification|upregulation of shell calcification Any process that activates or increases the frequency, rate or extent of shell calcification. GO:1905651 regulation of artery morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905651 regulation of arteriogenesis|regulation of arterial morphogenesis Any process that modulates the frequency, rate or extent of artery morphogenesis. GO:2000627 positive regulation of miRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000627 positive regulation of microRNA catabolic process Any process that activates or increases the frequency, rate or extent of miRNA catabolic process. GO:1905652 negative regulation of artery morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905652 down-regulation of artery morphogenesis|downregulation of arteriogenesis|down regulation of arteriogenesis|down-regulation of arterial morphogenesis|negative regulation of arterial morphogenesis|inhibition of arteriogenesis|downregulation of artery morphogenesis|down regulation of artery morphogenesis|inhibition of artery morphogenesis|downregulation of arterial morphogenesis|down regulation of arterial morphogenesis|inhibition of arterial morphogenesis|negative regulation of arteriogenesis|down-regulation of arteriogenesis Any process that stops, prevents or reduces the frequency, rate or extent of artery morphogenesis. GO:2000628 regulation of miRNA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000628 regulation of microRNA metabolic process Any process that modulates the frequency, rate or extent of miRNA metabolic process. GO:1905642 negative regulation of DNA methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905642 down regulation of DNA methylation|downregulation of DNA methylation|down-regulation of DNA methylation|inhibition of DNA methylation Any process that stops, prevents or reduces the frequency, rate or extent of DNA methylation. GO:1905643 positive regulation of DNA methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905643 up regulation of DNA methylation|activation of DNA methylation|up-regulation of DNA methylation|upregulation of DNA methylation Any process that activates or increases the frequency, rate or extent of DNA methylation. GO:1905644 regulation of FACT complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905644 regulation of Facilitates chromatin transcription complex assembly|regulation of Facilitates chromatin transcription complex formation|regulation of FACT complex formation Any process that modulates the frequency, rate or extent of FACT complex assembly. GO:1905645 negative regulation of FACT complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905645 inhibition of FACT complex formation|down regulation of Facilitates chromatin transcription complex formation|down regulation of Facilitates chromatin transcription complex assembly|inhibition of Facilitates chromatin transcription complex assembly|down regulation of FACT complex assembly|downregulation of Facilitates chromatin transcription complex formation|downregulation of FACT complex assembly|down-regulation of Facilitates chromatin transcription complex formation|negative regulation of Facilitates chromatin transcription complex formation|down-regulation of FACT complex assembly|negative regulation of FACT complex formation|down-regulation of FACT complex formation|inhibition of Facilitates chromatin transcription complex formation|negative regulation of Facilitates chromatin transcription complex assembly|down-regulation of Facilitates chromatin transcription complex assembly|inhibition of FACT complex assembly|downregulation of FACT complex formation|downregulation of Facilitates chromatin transcription complex assembly|down regulation of FACT complex formation Any process that stops, prevents or reduces the frequency, rate or extent of FACT complex assembly. UBERON:0008229 craniocervical region musculature biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008229 head or neck muscle|head or neck muscle|head muscles Musculature system of the pharyngeal and head regions. CHEBI:9889 urea-1-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_9889 GO:1905646 positive regulation of FACT complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905646 upregulation of FACT complex assembly|upregulation of FACT complex formation|upregulation of Facilitates chromatin transcription complex assembly|up regulation of Facilitates chromatin transcription complex formation|activation of Facilitates chromatin transcription complex formation|positive regulation of Facilitates chromatin transcription complex formation|up regulation of FACT complex assembly|activation of FACT complex formation|up-regulation of FACT complex formation|activation of FACT complex assembly|activation of Facilitates chromatin transcription complex assembly|up-regulation of Facilitates chromatin transcription complex assembly|up-regulation of Facilitates chromatin transcription complex formation|positive regulation of FACT complex formation|up-regulation of FACT complex assembly|up regulation of FACT complex formation|positive regulation of Facilitates chromatin transcription complex assembly|up regulation of Facilitates chromatin transcription complex assembly|upregulation of Facilitates chromatin transcription complex formation Any process that activates or increases the frequency, rate or extent of FACT complex assembly. CHEBI:16458 triacetate lactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16458 CHEBI:41425 (7R)-7-(4-carboxybutanamido)cephalosporanic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_41425 GO:1905647 proline import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905647 proline import into cell The directed movement of proline from outside of a cell into the cytoplasmic compartment. CHEBI:16459 pentanamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16459 GO:1905648 regulation of shell calcification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905648 Any process that modulates the frequency, rate or extent of shell calcification. CHEBI:16456 2-(2-hydroxyacyl)sphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16456 GO:2000620 positive regulation of histone H4-K16 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000620 positive regulation of histone H4 acetylation at K16 Any process that activates or increases the frequency, rate or extent of histone H4-K16 acetylation. GO:1905649 negative regulation of shell calcification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905649 down-regulation of shell calcification|inhibition of shell calcification|down regulation of shell calcification|downregulation of shell calcification Any process that stops, prevents or reduces the frequency, rate or extent of shell calcification. CHEBI:16457 S,S-dimethyl-beta-propiothetin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16457 CHEBI:16454 pantothenate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16454 GO:0051470 ectoine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051470 The directed movement of ectoine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid) is a tetrahydropyrimidine commonly synthesized by halophilic bacteria. GO:0002508 central tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002508 Tolerance induction in the central lymphoid organs: the thymus and bone marrow. CHEBI:16455 4,4-dimethyl-5alpha-cholest-7-en-3beta-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16455 GO:0051471 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051471 GO:0002509 central tolerance induction to self antigen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002509 Tolerance induction in the central lymphoid organs directed at self antigens. CHEBI:16452 oxaloacetate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16452 CHEBI:16453 1,4,5,6-tetrahydro-6-oxonicotinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16453 CHEBI:16450 2'-deoxyuridine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16450 GO:0051474 glucosylglycerol transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051474 Enables the transfer of a glucosylglycerol from one side of a membrane to the other. A glucosylglycerol is an alpha-D-glucopyranosyl-alpha-(1,2)-glycerol. IAO:0000233 term tracker item biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/IAO_0000233 IAO:0000233 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002504 peptide or polysaccharide antigen processing and presentation of via MHC class II The process in which an antigen-presenting cell expresses antigen (peptide or polysaccharide) on its cell surface in association with an MHC class II protein complex. GO:0051475 glucosylglycerol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051475 The directed movement of glucosylglycerol, alpha-D-glucopyranosyl-alpha-(1,2)-glycerol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0002505 antigen processing and presentation of polysaccharide antigen via MHC class II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002505 polysaccharide antigen processing and presentation via MHC class II The process in which an antigen-presenting cell expresses a polysaccharide antigen on its cell surface in association with an MHC class II protein complex. CHEBI:90396 (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90396 GO:0051472 glucosylglycerol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051472 glucosylglycerol metabolism The chemical reactions and pathways involving glucosylglycerol, alpha-D-glucopyranosyl-alpha-(1,2)-glycerol. CHEBI:90397 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90397 GO:0002506 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0002506 GO:0051473 glucosylglycerol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051473 glucosylglycerol biosynthesis|glucosylglycerol anabolism|glucosylglycerol synthesis|glucosylglycerol formation The chemical reactions and pathways resulting in the formation of glucosylglycerol, alpha-D-glucopyranosyl-alpha-(1,2)-glycerol. CHEBI:90398 (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90398 GO:0002507 tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002507 A process that directly activates any of the steps required for tolerance, a physiologic state in which the immune system does not react destructively against the components of an organism that harbors it or against antigens that are introduced to it. GO:0002511 central B cell receptor editing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002511 central B-lymphocyte receptor editing|central B-cell receptor editing|central B lymphocyte receptor editing Receptor editing occurring in B cells in the bone marrow. GO:0051489 regulation of filopodium assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051489 regulation of filopodia formation|regulation of filopodium formation|regulation of filopodia biosynthesis Any process that modulates the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone. CHEBI:90380 alpha-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-Cer biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90380 GO:0002512 central T cell tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002512 central T lymphocyte tolerance induction|central T-cell tolerance induction|central T-lymphocyte tolerance induction Tolerance induction of T cells in the thymus. CHEBI:90381 alpha-D-Gal-(1->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90381 GO:0051487 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051487 GO:0002513 tolerance induction to self antigen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002513 Tolerance induction directed at self antigens. GO:0002514 B cell tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002514 B lymphocyte tolerance induction|B-cell tolerance induction|B-lymphocyte tolerance induction A process involving any mechanism for tolerance induction in B cells. GO:0051488 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051488 CHEBI:90383 alpha-Neu5Gc-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90383 GO:0002510 central B cell tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002510 central B-cell tolerance induction|central B-lymphocyte tolerance induction|central B lymphocyte tolerance induction Tolerance induction of B cells in the bone marrow. GO:2000632 negative regulation of pre-miRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000632 negative regulation of pre-microRNA processing Any process that stops, prevents or reduces the frequency, rate or extent of pre-microRNA processing. GO:2000633 positive regulation of pre-miRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000633 positive regulation of pre-microRNA processing Any process that activates or increases the frequency, rate or extent of pre-microRNA processing. GO:2000634 regulation of primary miRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000634 regulation of pri-miRNA processing|regulation of primary microRNA processing Any process that modulates the frequency, rate or extent of primary microRNA processing. GO:2000635 negative regulation of primary miRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000635 negative regulation of primary microRNA processing|negative regulation of pri-miRNA processing Any process that stops, prevents or reduces the frequency, rate or extent of primary microRNA processing. GO:1905660 mitotic checkpoint complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905660 mitotic checkpoint complex formation|MCC formation|MCC assembly The aggregation, arrangement and bonding together of a set of components to form a mitotic checkpoint complex. GO:2000636 positive regulation of primary miRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000636 positive regulation of primary microRNA processing|positive regulation of pri-miRNA processing Any process that activates or increases the frequency, rate or extent of primary microRNA processing. GO:2000637 positive regulation of gene silencing by miRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000637 positive regulation of gene silencing by microRNA|positive regulation of microRNA-mediated gene silencing|positive regulation of miRNA-mediated gene silencing Any process that activates or increases the frequency, rate or extent of gene silencing by miRNA. GO:1905661 regulation of telomerase RNA reverse transcriptase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905661 regulation of telomerase, catalyst Any process that modulates the frequency, rate or extent of telomerase RNA reverse transcriptase activity. GO:1905662 negative regulation of telomerase RNA reverse transcriptase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905662 down-regulation of telomerase, catalyst|negative regulation of telomerase, catalyst|downregulation of telomerase, catalyst|down regulation of telomerase RNA reverse transcriptase activity|down regulation of telomerase, catalyst|downregulation of telomerase RNA reverse transcriptase activity|inhibition of telomerase, catalyst|down-regulation of telomerase RNA reverse transcriptase activity|inhibition of telomerase RNA reverse transcriptase activity Any process that stops, prevents or reduces the frequency, rate or extent of telomerase RNA reverse transcriptase activity. GO:2000638 regulation of SREBP signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000638 regulation of SREBP-mediated signaling pathway|regulation of SREBP-mediated signalling pathway Any process that modulates the frequency, rate or extent of the SREBP signaling pathway. GO:1905663 positive regulation of telomerase RNA reverse transcriptase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905663 positive regulation of telomerase, catalyst|up regulation of telomerase, catalyst|upregulation of telomerase RNA reverse transcriptase activity|upregulation of telomerase, catalyst|up regulation of telomerase RNA reverse transcriptase activity|activation of telomerase RNA reverse transcriptase activity|up-regulation of telomerase, catalyst|activation of telomerase, catalyst|up-regulation of telomerase RNA reverse transcriptase activity Any process that activates or increases the frequency, rate or extent of telomerase RNA reverse transcriptase activity. GO:2000639 negative regulation of SREBP signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000639 negative regulation of SREBP-mediated signaling pathway|negative regulation of SREBP-mediated signalling pathway Any process that stops, prevents or reduces the frequency, rate or extent of the SREBP signaling pathway. GO:1905653 positive regulation of artery morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905653 up-regulation of arterial morphogenesis|up regulation of arteriogenesis|activation of arterial morphogenesis|up regulation of artery morphogenesis|upregulation of arteriogenesis|positive regulation of arterial morphogenesis|up regulation of arterial morphogenesis|upregulation of artery morphogenesis|up-regulation of arteriogenesis|activation of arteriogenesis|upregulation of arterial morphogenesis|up-regulation of artery morphogenesis|activation of artery morphogenesis|positive regulation of arteriogenesis Any process that activates or increases the frequency, rate or extent of artery morphogenesis. GO:1905654 regulation of artery smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905654 Any process that modulates the frequency, rate or extent of artery smooth muscle contraction. GO:1905655 negative regulation of artery smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905655 down-regulation of artery smooth muscle contraction|downregulation of artery smooth muscle contraction|down regulation of artery smooth muscle contraction|inhibition of artery smooth muscle contraction Any process that stops, prevents or reduces the frequency, rate or extent of artery smooth muscle contraction. CHEBI:16449 alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16449 GO:1905656 positive regulation of artery smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905656 up-regulation of artery smooth muscle contraction|activation of artery smooth muscle contraction|up regulation of artery smooth muscle contraction|upregulation of artery smooth muscle contraction Any process that activates or increases the frequency, rate or extent of artery smooth muscle contraction. GO:1905657 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1905657 GO:1905658 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1905658 GO:2000630 positive regulation of miRNA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000630 positive regulation of microRNA metabolic process Any process that activates or increases the frequency, rate or extent of miRNA metabolic process. GO:1905659 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1905659 CHEBI:16445 stipitatonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16445 GO:2000631 regulation of pre-miRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000631 regulation of pre-microRNA processing Any process that modulates the frequency, rate or extent of pre-microRNA processing. CHEBI:16446 N-acetyl-alpha-D-glucosamine 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16446 GO:0002519 natural killer cell tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002519 NK cell tolerance induction Tolerance induction of natural killer cells. GO:0051481 negative regulation of cytosolic calcium ion concentration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051481 cytoplasmic calcium ion concentration reduction|cytosolic calcium ion concentration reduction|reduction of calcium ion concentration in cytoplasm|reduction of cytoplasmic calcium ion concentration|reduction of calcium ion concentration in cytosol|reduction of cytosolic calcium ion concentration Any process that decreases the concentration of calcium ions in the cytosol. CHEBI:16443 D-tagatose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16443 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051482 elevation of cytoplasmic calcium ion concentration during G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|elevation of calcium ion concentration in cytoplasm during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|elevation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway|elevation of cytosolic calcium ion concentration during G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|elevation of calcium ion concentration in cytosol during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|elevation of cytoplasmic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway|elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger Any process that increases the concentration of calcium ions in the cytosol that occurs as part of a PLC-activating G protein-coupled receptor signaling pathway. G-protein-activated PLC hydrolyses phosphatidylinositol-bisphosphate (PIP2) to release diacylglycerol (DAG) and inositol trisphosphate (IP3). IP3 then binds to calcium release channels in the endoplasmic reticulum (ER) to trigger calcium ion release into the cytosol. CHEBI:16444 2-acetyllactic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16444 CHEBI:16441 linamarin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16441 GO:0051480 regulation of cytosolic calcium ion concentration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051480 cytoplasmic calcium ion concentration regulation|regulation of calcium ion concentration in cytosol|cytosolic calcium ion concentration regulation|regulation of cytoplasmic calcium ion concentration|calcium ion homeostasis in cytoplasm|regulation of cytosolic calcium ion concentration|calcium ion homeostasis in cytosol|cytoplasmic calcium ion homeostasis|regulation of calcium ion concentration in cytoplasm Any process involved in the maintenance of an internal steady state of calcium ions within the cytosol of a cell or between the cytosol and its surroundings. GO:0002515 B cell anergy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002515 B-lymphocyte anergy|B-cell anergy|B lymphocyte anergy Any process contributing to anergy in B cells, a state of functional inactivation which is part of B cell tolerance induction. GO:0051485 terpenoid biosynthetic process, mevalonate-dependent biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051485 terpenoid synthesis, mevalonate-dependent|terpene biosynthesis, mevalonate-dependent|terpene biosynthetic process, mevalonate-dependent|terpenoid formation, mevalonate-dependent|terpenoid anabolism, mevalonate-dependent The chemical reactions and pathways resulting in the formation of terpenoids via isopentenyl diphosphate, synthesized by the mevalonate pathway. Isopentenyl diphosphate (IPP) is the fundamental unit in terpenoid biosynthesis, and in mevalonate-dependent terpenoid biosynthesis, acetate, in the form of acetyl-CoA, is converted to isopentenyl diphosphate (IPP) through a series of mevalonate intermediates. CHEBI:90384 alpha-Neu5Gc-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90384 GO:0002516 B cell deletion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002516 B-lymphocyte deletion|B-cell deletion|B lymphocyte deletion The apoptotic death of B cells which is part of B cell tolerance induction. GO:0051486 isopentenyl diphosphate biosynthetic process, mevalonate pathway involved in terpenoid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051486 isopentenyl diphosphate formation, mevalonate pathway, during terpenoid biosynthesis|isopentenyl diphosphate anabolism, mevalonate pathway, during terpenoid anabolism|isopentenyl diphosphate biosynthetic process, mevalonate pathway, during terpenoid biosynthetic process|isopentenyl diphosphate synthesis, mevalonate pathway, during terpenoid synthesis|isopentenyl diphosphate formation, mevalonate pathway, during terpenoid formation The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate pathway that contributes to terpenoid biosynthesis. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl diphosphate (IPP) through a series of mevalonate intermediates. CHEBI:16440 N-methyl-L-glutamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16440 GO:0051483 terpenoid biosynthetic process, mevalonate-independent biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051483 terpenoid anabolism, mevalonate-independent|terpenoid synthesis, mevalonate-independent|terpene biosynthesis, mevalonate-independent|terpene biosynthetic process, mevalonate-independent|terpenoid formation, mevalonate-independent|mevalonate-independent terpene biosynthetic process|mevalonate-independent terpene biosynthesis|mevalonate-independent terpenoid biosynthesis|mevalonate-independent terpenoid biosynthetic process The chemical reactions and pathways resulting in the formation of terpenoids, independent of mevalonate. Isopentenyl diphosphate (IPP) is the fundamental unit in terpenoid biosynthesis, and in mevalonate-independent biosynthesis, it is produced from pyruvate and glyceraldehyde 3-phosphate via intermediates including 1-deoxy-D-xylulose 5-phosphate. GO:0002517 T cell tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002517 T-cell tolerance induction|T-lymphocyte tolerance induction|T lymphocyte tolerance induction A process involving any mechanism for tolerance induction in T cells. GO:0002518 lymphocyte chemotaxis across high endothelial venule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002518 The movement of a lymphocyte to cross a high endothelial venule in response to an external stimulus. GO:0051484 isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051484 MetaCyc:NONMEVIPP-PWY isopentenyl diphosphate synthesis, mevalonate-independent pathway, during terpenoid synthesis|isopentenyl diphosphate formation, mevalonate-independent pathway, during terpenoid formation|isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway involved in terpenoid biosynthetic process|isopentenyl diphosphate formation, mevalonate-independent pathway, during terpenoid biosynthesis|isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway, during terpenoid biosynthetic process|isopentenyl diphosphate anabolism, mevalonate-independent pathway, during terpenoid anabolism The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate-independent pathway that contributes to terpenoid biosynthesis. Isopentenyl diphosphate (IPP) is the fundamental unit in isoprenoid biosynthesis and is biosynthesized from pyruvate and glyceraldehyde 3-phosphate via intermediates, including 1-deoxy-D-xylulose 5-phosphate. UBERON:0023879 neural system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0023879 neural system A set of neural structures that subserve a specific function, e.g., visual system CHEBI:16480 nitric oxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16480 GO:0051498 syn-copalyl diphosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051498 MetaCyc:RXN-8528|EC:5.5.1.14|RHEA:25524 diterpene cyclase activity Catalysis of the reaction: geranylgeranyl diphosphate = 9alpha-copalyl diphosphate. GO:0051499 D-aminoacyl-tRNA deacylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051499 MetaCyc:RXN-15041|EC:3.1.1.96|RHEA:13953 Catalysis of the reaction: D-aminoacyl-tRNA = D-amino acid + tRNA. Hydrolysis of the removal of D-amino acids from residues in charged tRNA. GO:2000643 positive regulation of early endosome to late endosome transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000643 Any process that activates or increases the frequency, rate or extent of early endosome to late endosome transport. GO:2000644 regulation of receptor catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000644 regulation of receptor catabolism|regulation of receptor degradation|regulation of receptor breakdown Any process that modulates the frequency, rate or extent of receptor catabolic process. GO:2000645 negative regulation of receptor catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000645 negative regulation of receptor degradation|negative regulation of receptor breakdown|negative regulation of receptor catabolism Any process that stops, prevents or reduces the frequency, rate or extent of receptor catabolic process. GO:2000646 positive regulation of receptor catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000646 positive regulation of receptor degradation|positive regulation of receptor catabolism|positive regulation of receptor breakdown Any process that activates or increases the frequency, rate or extent of receptor catabolic process. GO:1905670 TORC2 complex disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905670 TORC 2 complex disassembly|TORC2 disassembly|rapamycin and nutrient-insensitive TOR complex disassembly|mTORC2 disassembly|TOR complex 2 disassembly The disaggregation of a TORC2 complex into its constituent components. GO:2000647 negative regulation of stem cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000647 Any process that stops, prevents or reduces the frequency, rate or extent of stem cell proliferation. GO:1905671 regulation of lysosome organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905671 regulation of lysosome organization and biogenesis|regulation of lysosome organisation Any process that modulates the frequency, rate or extent of lysosome organization. GO:1905672 negative regulation of lysosome organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905672 down regulation of lysosome organization|downregulation of lysosome organization and biogenesis|downregulation of lysosome organization|down regulation of lysosome organization and biogenesis|negative regulation of lysosome organisation|down-regulation of lysosome organisation|inhibition of lysosome organisation|down-regulation of lysosome organization|inhibition of lysosome organization and biogenesis|inhibition of lysosome organization|negative regulation of lysosome organization and biogenesis|down-regulation of lysosome organization and biogenesis|down regulation of lysosome organisation|downregulation of lysosome organisation Any process that stops, prevents or reduces the frequency, rate or extent of lysosome organization. GO:2000648 positive regulation of stem cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000648 Any process that activates or increases the frequency, rate or extent of stem cell proliferation. GO:1905673 positive regulation of lysosome organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905673 up regulation of lysosome organization and biogenesis|up regulation of lysosome organisation|activation of lysosome organisation|positive regulation of lysosome organisation|up regulation of lysosome organization|activation of lysosome organization|upregulation of lysosome organization and biogenesis|up-regulation of lysosome organisation|up-regulation of lysosome organization and biogenesis|up-regulation of lysosome organization|upregulation of lysosome organisation|activation of lysosome organization and biogenesis|positive regulation of lysosome organization and biogenesis|upregulation of lysosome organization Any process that activates or increases the frequency, rate or extent of lysosome organization. GO:2000649 regulation of sodium ion transmembrane transporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000649 regulation of sodium transporter activity Any process that modulates the frequency, rate or extent of sodium ion transmembrane transporter activity. GO:1905674 regulation of adaptive immune memory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905674 Any process that modulates the frequency, rate or extent of adaptive immune memory response. GO:1905664 regulation of calcium ion import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905664 Any process that modulates the frequency, rate or extent of calcium ion import across plasma membrane. GO:1905665 positive regulation of calcium ion import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905665 upregulation of calcium ion import across plasma membrane|up regulation of calcium ion import across plasma membrane|activation of calcium ion import across plasma membrane|up-regulation of calcium ion import across plasma membrane Any process that activates or increases the frequency, rate or extent of calcium ion import across plasma membrane. GO:1905666 regulation of protein localization to endosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905666 regulation of protein localisation in endosome|regulation of protein localization in endosome Any process that modulates the frequency, rate or extent of protein localization to endosome. GO:1905667 negative regulation of protein localization to endosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905667 downregulation of protein localization to endosome|down-regulation of protein localization in endosome|negative regulation of protein localization in endosome|downregulation of protein localisation in endosome|down regulation of protein localization to endosome|inhibition of protein localization to endosome|down regulation of protein localisation in endosome|inhibition of protein localisation in endosome|downregulation of protein localization in endosome|down regulation of protein localization in endosome|inhibition of protein localization in endosome|down-regulation of protein localization to endosome|negative regulation of protein localisation in endosome|down-regulation of protein localisation in endosome Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to endosome. GO:1905668 positive regulation of protein localization to endosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905668 up regulation of protein localization to endosome|positive regulation of protein localisation in endosome|up regulation of protein localisation in endosome|positive regulation of protein localization in endosome|upregulation of protein localization to endosome|up regulation of protein localization in endosome|upregulation of protein localisation in endosome|activation of protein localization to endosome|up-regulation of protein localization to endosome|upregulation of protein localization in endosome|up-regulation of protein localisation in endosome|activation of protein localisation in endosome|activation of protein localization in endosome|up-regulation of protein localization in endosome Any process that activates or increases the frequency, rate or extent of protein localization to endosome. GO:1905669 TORC1 complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905669 nutrient sensitive complex assembly|TORC 1 complex assembly|dTORC1 formation|TORC1 formation|rapamycin and nutrient-sensitive TOR complex formation|mTORC1 assembly|mTORC1 formation|TOR complex 1 assembly|dTORC1 assembly|TOR complex 1 formation|TORC1 complex formation|dTOR/dRaptor complex formation|rapamycin and nutrient-sensitive TOR complex assembly|TORC1 assembly|TORC 1 complex formation|nutrient sensitive complex formation|dTOR/dRaptor complex assembly The aggregation, arrangement and bonding together of a set of components to form a TORC1 complex. GO:2000640 positive regulation of SREBP signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000640 positive regulation of SREBP-mediated signalling pathway|positive regulation of SREBP-mediated signaling pathway Any process that activates or increases the frequency, rate or extent of the SREBP signaling pathway. CHEBI:16478 N-acetyl-beta-D-glucosaminyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,3)-N-acetyl-D-galactosaminyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16478 GO:2000641 regulation of early endosome to late endosome transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000641 Any process that modulates the frequency, rate or extent of early endosome to late endosome transport. GO:2000642 negative regulation of early endosome to late endosome transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000642 Any process that stops, prevents or reduces the frequency, rate or extent of early endosome to late endosome transport. CHEBI:16479 streptomycin 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16479 CHEBI:41402 carboxymethyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_41402 GO:0051492 regulation of stress fiber assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051492 regulation of stress fibre biosynthesis|regulation of stress fibre formation Any process that modulates the frequency, rate or extent of the assembly of a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts. GO:0051493 regulation of cytoskeleton organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051493 regulation of cytoskeleton organisation|regulation of cytoskeleton organization and biogenesis Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures. GO:0051490 negative regulation of filopodium assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051490 down regulation of filopodium formation|inhibition of filopodium formation|negative regulation of filopodium formation|negative regulation of filopodia biosynthesis|down-regulation of filopodium formation|negative regulation of filopodia formation|downregulation of filopodium formation Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone. CHEBI:16474 NADPH biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16474 GO:0051491 positive regulation of filopodium assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051491 upregulation of filopodium formation|stimulation of filopodium formation|up-regulation of filopodium formation|positive regulation of filopodium formation|activation of filopodium formation|positive regulation of filopodia biosynthesis|positive regulation of filopodia formation|up regulation of filopodium formation Any process that activates or increases the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone. CHEBI:16475 2-[3-carboxy-3-(methylammonio)propyl]-L-histidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16475 GO:0051496 positive regulation of stress fiber assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051496 positive regulation of stress fibre biosynthesis|up regulation of stress fiber formation|upregulation of stress fiber formation|stimulation of stress fiber formation|activation of stress fiber formation|up-regulation of stress fiber formation|positive regulation of stress fibre formation Any process that activates or increases the frequency, rate or extent of the assembly of a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts. CHEBI:16472 pentan-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16472 GO:0051497 negative regulation of stress fiber assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051497 negative regulation of stress fibre biosynthesis|downregulation of stress fiber formation|inhibition of stress fiber formation|down regulation of stress fiber formation|negative regulation of stress fibre formation|down-regulation of stress fiber formation Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts. CHEBI:16473 cortisol 21-sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16473 GO:0051494 negative regulation of cytoskeleton organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051494 down regulation of cytoskeleton organization|downregulation of cytoskeleton organization|negative regulation of cytoskeleton organisation|down-regulation of cytoskeleton organization|inhibition of cytoskeleton organization|negative regulation of cytoskeleton organization and biogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures. UBERON:0008202 bone of hip region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008202 CHEBI:16470 glyceollin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16470 GO:0051495 positive regulation of cytoskeleton organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051495 positive regulation of cytoskeleton organization and biogenesis|positive regulation of cytoskeleton organisation|up regulation of cytoskeleton organization|activation of cytoskeleton organization|stimulation of cytoskeleton organization|up-regulation of cytoskeleton organization|upregulation of cytoskeleton organization Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures. UBERON:0008203 pelvic cavity biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008203 cavitas pelvis|space of pelvic compartment The part of the ventral body cavity that is within the pelvis. CHEBI:16471 (dimethylsulfonio)acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16471 GO:0099401 caveola bulb biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0099401 caveola crater The region of a caveola that extends into the cytoplasm, excluding the neck (rim). This region is associated with intracellular caveola proteins. GO:0099402 plant organ development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099402 development of a plant organ Development of a plant organ, a multi-tissue plant structure that forms a functional unit. GO:0099400 caveola neck biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0099400 A membrane microdomain that forms a necklace around the bulb (crater) of a caveola. Intramembrane particles are concentrated in this region and cytoskeletal components, including actin, are highly enriched in the area underlying it. GO:2000654 regulation of cellular response to testosterone stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000654 Any process that modulates the frequency, rate or extent of cellular response to testosterone stimulus. GO:2000655 negative regulation of cellular response to testosterone stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000655 Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to testosterone stimulus. GO:2000656 regulation of apolipoprotein binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000656 Any process that modulates the frequency, rate or extent of apolipoprotein binding. GO:1905680 regulation of innate immunity memory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905680 Any process that modulates the frequency, rate or extent of innate immunity memory response. GO:1905681 negative regulation of innate immunity memory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905681 down regulation of innate immunity memory response|downregulation of innate immunity memory response|down-regulation of innate immunity memory response|inhibition of innate immunity memory response Any process that stops, prevents or reduces the frequency, rate or extent of innate immunity memory response. GO:2000657 negative regulation of apolipoprotein binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000657 Any process that stops, prevents or reduces the frequency, rate or extent of apolipoprotein binding. GO:1905682 positive regulation of innate immunity memory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905682 up regulation of innate immunity memory response|activation of innate immunity memory response|up-regulation of innate immunity memory response|upregulation of innate immunity memory response Any process that activates or increases the frequency, rate or extent of innate immunity memory response. GO:2000658 positive regulation of apolipoprotein binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000658 Any process that activates or increases the frequency, rate or extent of apolipoprotein binding. GO:2000659 regulation of interleukin-1-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000659 regulation of interleukin-1 alpha-mediated signaling pathway|regulation of interleukin-1-mediated signalling pathway|regulation of interleukin-1 beta-mediated signaling pathway|regulation of IL-1-mediated signaling pathway|regulation of IL-1 beta-mediated signaling pathway|regulation of IL-1 alpha-mediated signaling pathway Any process that modulates the frequency, rate or extent of interleukin-1-mediated signaling pathway. GO:1905683 peroxisome disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905683 peroxisomal disassembly The disaggregation of a peroxisome into its constituent components. GO:1905684 regulation of plasma membrane repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905684 Any process that modulates the frequency, rate or extent of plasma membrane repair. GO:1905685 negative regulation of plasma membrane repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905685 downregulation of plasma membrane repair|down regulation of plasma membrane repair|inhibition of plasma membrane repair|down-regulation of plasma membrane repair Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane repair. GO:1905675 negative regulation of adaptive immune memory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905675 down regulation of adaptive immune memory response|downregulation of adaptive immune memory response|down-regulation of adaptive immune memory response|inhibition of adaptive immune memory response Any process that stops, prevents or reduces the frequency, rate or extent of adaptive immune memory response. GO:1905676 positive regulation of adaptive immune memory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905676 up-regulation of adaptive immune memory response|upregulation of adaptive immune memory response|up regulation of adaptive immune memory response|activation of adaptive immune memory response Any process that activates or increases the frequency, rate or extent of adaptive immune memory response. GO:1905677 regulation of adaptive immune effector response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905677 Any process that modulates the frequency, rate or extent of adaptive immune effector response. GO:1905678 negative regulation of adaptive immune effector response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905678 down regulation of adaptive immune effector response|downregulation of adaptive immune effector response|down-regulation of adaptive immune effector response|inhibition of adaptive immune effector response Any process that stops, prevents or reduces the frequency, rate or extent of adaptive immune effector response. GO:1905679 positive regulation of adaptive immune effector response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905679 up regulation of adaptive immune effector response|activation of adaptive immune effector response|up-regulation of adaptive immune effector response|upregulation of adaptive immune effector response Any process that activates or increases the frequency, rate or extent of adaptive immune effector response. GO:2000650 negative regulation of sodium ion transmembrane transporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000650 negative regulation of sodium transporter activity Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transporter activity. CHEBI:16469 17beta-estradiol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16469 GO:2000651 positive regulation of sodium ion transmembrane transporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000651 positive regulation of sodium transporter activity Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transporter activity. GO:2000652 regulation of secondary cell wall biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000652 regulation of secondary cell wall synthesis|regulation of plant-type secondary cell wall biogenesis|regulation of secondary cell wall formation|regulation of cellulose and pectin-containing secondary cell wall biogenesis|regulation of secondary cell wall biosynthetic process|regulation of secondary cell wall anabolism Any process that modulates the frequency, rate or extent of secondary cell wall biogenesis. CHEBI:16467 L-arginine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16467 GO:2000653 regulation of genetic imprinting biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000653 regulation of DNA imprinting Any process that modulates the frequency, rate or extent of genetic imprinting. CHEBI:16468 maleylacetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16468 CHEBI:16466 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16466 CHEBI:16463 N-methylethanolamine phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16463 CHEBI:16464 salicyl alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16464 CHEBI:16461 tauropine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16461 GO:0099403 maintenance of mitotic sister chromatid cohesion, telomeric biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099403 maintenance of mitotic sister chromatin cohesion at telomere|maintenance of telomeric mitotic sister chromatin cohesion|maintenance of sister chromatin cohesion at telomere at mitosis The process in which the association between sister chromatids of a replicated chromosome along the length of the telomeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle. GO:0099404 mitotic sister chromatid cohesion, telomeric biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0099404 telomeric mitotic sister chromatin cohesion|sister chromatid cohesion at telomere at mitosis|mitotic sister chromatid cohesion at telomere The cell cycle process in which telomeres of sister chromatids are joined during mitosis. CHEBI:16460 polyprenol phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16460 GO:1905690 nucleus disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905690 cell nucleus disassembly The disaggregation of a nucleus into its constituent components. GO:1905691 lipid droplet disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905691 lipid droplet reserve breakdown|adiposome disassembly|lipid particle disassembly|lipid body disassembly The disaggregation of a lipid particle into its constituent components. GO:1905692 endoplasmic reticulum disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905692 ER disassembly The disaggregation of an endoplasmic reticulum into its constituent components. GO:1905693 regulation of phosphatidic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905693 regulation of phosphatidic acid synthesis|regulation of phosphatidic acid formation|regulation of phosphatidic acid biosynthesis|regulation of phosphatidic acid anabolism Any process that modulates the frequency, rate or extent of phosphatidic acid biosynthetic process. GO:1905694 negative regulation of phosphatidic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905694 down regulation of phosphatidic acid formation|downregulation of phosphatidic acid biosynthesis|downregulation of phosphatidic acid biosynthetic process|downregulation of phosphatidic acid synthesis|downregulation of phosphatidic acid formation|down regulation of phosphatidic acid biosynthesis|down regulation of phosphatidic acid biosynthetic process|down-regulation of phosphatidic acid anabolism|negative regulation of phosphatidic acid anabolism|inhibition of phosphatidic acid biosynthetic process|inhibition of phosphatidic acid biosynthesis|down-regulation of phosphatidic acid synthesis|negative regulation of phosphatidic acid synthesis|down-regulation of phosphatidic acid formation|inhibition of phosphatidic acid anabolism|negative regulation of phosphatidic acid formation|inhibition of phosphatidic acid synthesis|inhibition of phosphatidic acid formation|negative regulation of phosphatidic acid biosynthesis|down-regulation of phosphatidic acid biosynthetic process|down-regulation of phosphatidic acid biosynthesis|down regulation of phosphatidic acid anabolism|down regulation of phosphatidic acid synthesis|downregulation of phosphatidic acid anabolism Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidic acid biosynthetic process. GO:1905695 positive regulation of phosphatidic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905695 upregulation of phosphatidic acid formation|up regulation of phosphatidic acid biosynthesis|up regulation of phosphatidic acid biosynthetic process|up regulation of phosphatidic acid anabolism|activation of phosphatidic acid anabolism|positive regulation of phosphatidic acid anabolism|up regulation of phosphatidic acid synthesis|activation of phosphatidic acid synthesis|positive regulation of phosphatidic acid synthesis|up regulation of phosphatidic acid formation|upregulation of phosphatidic acid biosynthesis|activation of phosphatidic acid formation|upregulation of phosphatidic acid biosynthetic process|positive regulation of phosphatidic acid formation|up-regulation of phosphatidic acid anabolism|activation of phosphatidic acid biosynthesis|up-regulation of phosphatidic acid biosynthesis|up-regulation of phosphatidic acid synthesis|activation of phosphatidic acid biosynthetic process|up-regulation of phosphatidic acid biosynthetic process|up-regulation of phosphatidic acid formation|upregulation of phosphatidic acid anabolism|upregulation of phosphatidic acid synthesis|positive regulation of phosphatidic acid biosynthesis Any process that activates or increases the frequency, rate or extent of phosphatidic acid biosynthetic process. GO:1905696 regulation of polysome binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905696 regulation of polyribosome binding Any process that modulates the frequency, rate or extent of polysome binding. GO:1905686 positive regulation of plasma membrane repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905686 up regulation of plasma membrane repair|upregulation of plasma membrane repair|up-regulation of plasma membrane repair|activation of plasma membrane repair Any process that activates or increases the frequency, rate or extent of plasma membrane repair. GO:1905687 regulation of diacylglycerol kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905687 regulation of sn-1,2-diacylglycerol kinase activity|regulation of 1,2-diacylglycerol kinase (phosphorylating)|regulation of CTP:diacylglycerol kinase activity|regulation of ATP:diacylglycerol phosphotransferase activity|regulation of 1,2-diacylglycerol kinase activity|regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|regulation of arachidonoyl-specific diacylglycerol kinase activity|regulation of DG kinase activity|regulation of diglyceride kinase activity|regulation of diacylglycerol:ATP kinase activity|regulation of DGK activity Any process that modulates the frequency, rate or extent of diacylglycerol kinase activity. CHEBI:16419 limonoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16419 GO:1905688 negative regulation of diacylglycerol kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905688 inhibition of DGK activity|negative regulation of diglyceride kinase activity|down-regulation of diglyceride kinase activity|down-regulation of ATP:diacylglycerol phosphotransferase activity|negative regulation of ATP:diacylglycerol phosphotransferase activity|down regulation of sn-1,2-diacylglycerol kinase activity|down regulation of 1,2-diacylglycerol kinase (phosphorylating)|downregulation of CTP:diacylglycerol kinase activity|downregulation of diacylglycerol kinase activity|down-regulation of 1,2-diacylglycerol kinase activity|negative regulation of 1,2-diacylglycerol kinase activity|inhibition of diacylglycerol:ATP kinase activity|negative regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|downregulation of sn-1,2-diacylglycerol kinase activity|down-regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|inhibition of diglyceride kinase activity|downregulation of 1,2-diacylglycerol kinase (phosphorylating)|negative regulation of arachidonoyl-specific diacylglycerol kinase activity|down-regulation of arachidonoyl-specific diacylglycerol kinase activity|down regulation of CTP:diacylglycerol kinase activity|down regulation of diacylglycerol kinase activity|inhibition of diacylglycerol kinase activity|negative regulation of DG kinase activity|downregulation of ATP:diacylglycerol phosphotransferase activity|down-regulation of DG kinase activity|downregulation of 1,2-diacylglycerol kinase activity|inhibition of CTP:diacylglycerol kinase activity|down-regulation of sn-1,2-diacylglycerol kinase activity|negative regulation of sn-1,2-diacylglycerol kinase activity|down regulation of ATP:diacylglycerol phosphotransferase activity|downregulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|down-regulation of 1,2-diacylglycerol kinase (phosphorylating)|negative regulation of 1,2-diacylglycerol kinase (phosphorylating)|downregulation of arachidonoyl-specific diacylglycerol kinase activity|down-regulation of diacylglycerol:ATP kinase activity|down regulation of 1,2-diacylglycerol kinase activity|negative regulation of diacylglycerol:ATP kinase activity|negative regulation of DGK activity|down-regulation of DGK activity|down regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|inhibition of 1,2-diacylglycerol kinase activity|downregulation of DG kinase activity|down regulation of diglyceride kinase activity|down regulation of arachidonoyl-specific diacylglycerol kinase activity|inhibition of arachidonoyl-specific diacylglycerol kinase activity|inhibition of sn-1,2-diacylglycerol kinase activity|inhibition of ATP:diacylglycerol phosphotransferase activity|inhibition of 1,2-diacylglycerol kinase (phosphorylating)|downregulation of diglyceride kinase activity|down regulation of DG kinase activity|inhibition of DG kinase activity|down-regulation of CTP:diacylglycerol kinase activity|negative regulation of CTP:diacylglycerol kinase activity|inhibition of ATP:1,2-diacylglycerol 3-phosphotransferase activity|downregulation of diacylglycerol:ATP kinase activity|down-regulation of diacylglycerol kinase activity|downregulation of DGK activity|down regulation of diacylglycerol:ATP kinase activity|down regulation of DGK activity Any process that stops, prevents or reduces the frequency, rate or extent of diacylglycerol kinase activity. GO:1905689 positive regulation of diacylglycerol kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905689 activation of arachidonoyl-specific diacylglycerol kinase activity|up regulation of diacylglycerol kinase activity|up regulation of CTP:diacylglycerol kinase activity|activation of ATP:diacylglycerol phosphotransferase activity|upregulation of diacylglycerol:ATP kinase activity|upregulation of DGK activity|up-regulation of DG kinase activity|activation of DG kinase activity|activation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|positive regulation of ATP:diacylglycerol phosphotransferase activity|up-regulation of diglyceride kinase activity|up regulation of sn-1,2-diacylglycerol kinase activity|up regulation of ATP:diacylglycerol phosphotransferase activity|positive regulation of 1,2-diacylglycerol kinase activity|up regulation of 1,2-diacylglycerol kinase (phosphorylating)|positive regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|positive regulation of sn-1,2-diacylglycerol kinase activity|activation of sn-1,2-diacylglycerol kinase activity|positive regulation of arachidonoyl-specific diacylglycerol kinase activity|upregulation of diacylglycerol kinase activity|up regulation of 1,2-diacylglycerol kinase activity|upregulation of CTP:diacylglycerol kinase activity|up-regulation of DGK activity|up-regulation of diacylglycerol:ATP kinase activity|activation of 1,2-diacylglycerol kinase (phosphorylating)|positive regulation of 1,2-diacylglycerol kinase (phosphorylating)|up regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|up regulation of arachidonoyl-specific diacylglycerol kinase activity|activation of DGK activity|positive regulation of DG kinase activity|upregulation of diglyceride kinase activity|up regulation of DG kinase activity|activation of diacylglycerol:ATP kinase activity|upregulation of ATP:diacylglycerol phosphotransferase activity|up-regulation of CTP:diacylglycerol kinase activity|up-regulation of diacylglycerol kinase activity|upregulation of 1,2-diacylglycerol kinase activity|activation of diacylglycerol kinase activity|up-regulation of sn-1,2-diacylglycerol kinase activity|positive regulation of diacylglycerol:ATP kinase activity|up-regulation of 1,2-diacylglycerol kinase (phosphorylating)|upregulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|upregulation of arachidonoyl-specific diacylglycerol kinase activity|positive regulation of DGK activity|up regulation of DGK activity|up regulation of diacylglycerol:ATP kinase activity|activation of CTP:diacylglycerol kinase activity|upregulation of DG kinase activity|up regulation of diglyceride kinase activity|up-regulation of ATP:diacylglycerol phosphotransferase activity|activation of diglyceride kinase activity|positive regulation of diglyceride kinase activity|up-regulation of 1,2-diacylglycerol kinase activity|upregulation of sn-1,2-diacylglycerol kinase activity|activation of 1,2-diacylglycerol kinase activity|positive regulation of CTP:diacylglycerol kinase activity|upregulation of 1,2-diacylglycerol kinase (phosphorylating)|up-regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|up-regulation of arachidonoyl-specific diacylglycerol kinase activity Any process that activates or increases the frequency, rate or extent of diacylglycerol kinase activity. CHEBI:16414 L-valine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16414 CHEBI:16415 protopine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16415 CHEBI:16412 lipopolysaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16412 CHEBI:16413 but-2-yne-1,4-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16413 CHEBI:16410 pyridoxamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16410 CHEBI:16411 indole-3-acetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16411 UBERON:0008266 periodontal ligament biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008266 peridontal fiber|alveolar periosteum|periodontal fiber|peridontal ligament|periodontium|alveolodental ligament|peridontal membrane|alveolodental membrane|odontoperiosteum|peridontium|peridontal ligament fibre|fibra periodontalis|desmodontium|paradentium|peridontal fibre|peridontal ligament fiber|PDL|periodontal fibre|peridental membrane The fibrous connective tissue that surrounds the root of a tooth, separating it from and attaching it to the alveolar bone. It extends from the base of the gingival mucosa to the fundus of the bony socket, and its main function is to hold the tooth in its socket[BTO]. CHEBI:16409 5-pyridoxic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16409 GO:1905697 negative regulation of polysome binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905697 down-regulation of polysome binding|downregulation of polyribosome binding|down regulation of polyribosome binding|downregulation of polysome binding|inhibition of polyribosome binding|down regulation of polysome binding|inhibition of polysome binding|down-regulation of polyribosome binding|negative regulation of polyribosome binding Any process that stops, prevents or reduces the frequency, rate or extent of polysome binding. GO:1905698 positive regulation of polysome binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905698 positive regulation of polyribosome binding|up regulation of polyribosome binding|up regulation of polysome binding|upregulation of polyribosome binding|upregulation of polysome binding|up-regulation of polyribosome binding|activation of polyribosome binding|up-regulation of polysome binding|activation of polysome binding Any process that activates or increases the frequency, rate or extent of polysome binding. CHEBI:16408 vomilenine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16408 GO:1905699 regulation of xenobiotic detoxification by transmembrane export across the plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905699 regulation of drug transmembrane export|regulation of xenobiotic transmembrane export Any process that modulates the frequency, rate or extent of drug transmembrane export. CHEBI:16405 beta-D-Xylp-(1->6)-beta-D-Glcp biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16405 CHEBI:16406 5'-acylphosphoadenosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16406 CHEBI:16404 3-oxoglycyrrhetinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16404 CHEBI:16400 gossypetin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16400 UBERON:0008255 right clavicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008255 A clavicle that is in the right side of a entire appendicular skeleton. UBERON:0008256 left clavicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008256 A clavicle that is in the left side of a entire appendicular skeleton. GO:2000607 negative regulation of cell proliferation involved in mesonephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000607 Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in mesonephros development. GO:2000608 positive regulation of cell proliferation involved in mesonephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000608 Any process that activates or increases the frequency, rate or extent of cell proliferation involved in mesonephros development. GO:2000609 regulation of thyroid hormone generation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000609 Any process that modulates the frequency, rate or extent of thyroid hormone generation. GO:2000600 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2000600 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000601 positive regulation of branched actin filament nucleation|positive regulation of actin filament branch nucleation Any process that activates or increases the frequency, rate or extent of Arp2/3 complex-mediated actin nucleation. GO:2000602 obsolete regulation of interphase of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000602 regulation of interphase of mitotic cell cycle OBSOLETE. Any process that modulates the frequency, rate or extent of interphase of mitotic cell cycle. GO:2000603 regulation of secondary growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000603 Any process that modulates the frequency, rate or extent of secondary growth. GO:2000604 negative regulation of secondary growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000604 Any process that stops, prevents or reduces the frequency, rate or extent of secondary growth. GO:2000605 positive regulation of secondary growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000605 Any process that activates or increases the frequency, rate or extent of secondary growth. GO:2000606 regulation of cell proliferation involved in mesonephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000606 Any process that modulates the frequency, rate or extent of cell proliferation involved in mesonephros development. CHEBI:16439 N-(carboxymethyl)-D-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16439 CHEBI:16436 CDP-choline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16436 CHEBI:16437 N-acetyl-L-histidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16437 CHEBI:16434 N-hydroxy-4-acetylaminobiphenyl biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16434 CHEBI:16435 UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16435 CHEBI:16433 trans-caffeic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16433 CHEBI:16430 precorrin-4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16430 CHEBI:16431 limonene 1,2-epoxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16431 UBERON:0008243 upper back muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008243 A muscle of back that is part of a dorsal thoracic segment of trunk. GO:2000618 regulation of histone H4-K16 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000618 regulation of histone H4 acetylation at K16 Any process that modulates the frequency, rate or extent of histone H4-K16 acetylation. GO:2000619 negative regulation of histone H4-K16 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000619 negative regulation of histone H4 acetylation at K16 Any process that stops, prevents or reduces the frequency, rate or extent of histone H4-K16 acetylation. GO:2000610 negative regulation of thyroid hormone generation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000610 Any process that stops, prevents or reduces the frequency, rate or extent of thyroid hormone generation. GO:2000611 positive regulation of thyroid hormone generation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000611 Any process that activates or increases the frequency, rate or extent of thyroid hormone generation. GO:2000612 regulation of thyroid-stimulating hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000612 regulation of thyroid stimulating hormone secretion|regulation of TSH secretion Any process that modulates the frequency, rate or extent of thyroid-stimulating hormone secretion. GO:2000613 negative regulation of thyroid-stimulating hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000613 negative regulation of thyroid stimulating hormone secretion|negative regulation of TSH secretion Any process that stops, prevents or reduces the frequency, rate or extent of thyroid-stimulating hormone secretion. GO:2000614 positive regulation of thyroid-stimulating hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000614 positive regulation of thyroid stimulating hormone secretion|positive regulation of TSH secretion Any process that activates or increases the frequency, rate or extent of thyroid-stimulating hormone secretion. GO:2000615 regulation of histone H3-K9 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000615 regulation of histone H3K9 acetylation|regulation of histone H3 acetylation at K9 Any process that modulates the frequency, rate or extent of histone H3-K9 acetylation. GO:2000616 negative regulation of histone H3-K9 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000616 negative regulation of histone H3K9 acetylation|negative regulation of histone H3 acetylation at K9 Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K9 acetylation. GO:2000617 positive regulation of histone H3-K9 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000617 positive regulation of histone H3K9 acetylation|positive regulation of histone H3 acetylation at K9 Any process that activates or increases the frequency, rate or extent of histone H3-K9 acetylation. CHEBI:16427 mono(glucosyluronic acid)bilirubin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16427 CHEBI:16428 4-coumaroylshikimic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16428 CHEBI:16425 16-epivellosimine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16425 CHEBI:16426 3-(imidazol-4-yl)-2-oxopropyl dihydrogen phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16426 CHEBI:16423 (9Z)-octadec-9-en-12-ynoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16423 CHEBI:16424 phenylacetaldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16424 IAO:0000226 placeholder removed biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/IAO_0000226 CHEBI:16421 1-deoxy-D-altro-heptulose 7-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16421 IAO:0000227 terms merged biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/IAO_0000227 CHEBI:16422 androst-4-ene-3,17-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16422 UBERON:0008231 dorsal thoracic segment of trunk biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008231 dorsum of thorax|back of thorax|thoracic back|thoracic part of back|posterior part of thorax|upper back Subdivision of thorax, which in humans is the posterior part of the thorax and is demarcated from the chest by the external surface of the posterolateral part of the rib cage and the anterior surface of the thoracic vertebral column; together with the chest, it constitutes the thorax. IAO:0000224 core biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/IAO_0000224 Core is an instance of a grouping of terms from an ontology or ontologies. It is used by the ontology to identify main classes. IAO:0000225 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/IAO_0000225 GO:0002467 germinal center formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002467 The process in which germinal centers form. A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation. GO:0002468 dendritic cell antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002468 The process in which a dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. GO:0002469 myeloid dendritic cell antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002469 The process in which a myeloid dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. GO:0002463 central tolerance induction to nonself antigen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002463 Tolerance induction to nonself antigens in the central lymphoid organs. GO:0002464 peripheral tolerance induction to nonself antigen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002464 Tolerance induction to nonself antigens in the periphery. GO:0002465 peripheral tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002465 Tolerance induction in the peripheral lymphoid tissues: blood, lymph nodes, spleen, and mucosal-associated lymphoid tissues. GO:0002466 peripheral tolerance induction to self antigen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002466 Tolerance induction to self antigens in the peripheral lymphoid tissues: blood, lymph nodes, spleen, and mucosal-associated lymphoid tissues. GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002460 An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus. GO:0002461 tolerance induction dependent upon immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002461 immune response-dependent tolerance induction Tolerance induction dependent upon an immune response, typically a response by a mature T or B cell in the periphery resulting tolerance towards an antigen via induction of anergy, cellular deletion, or regulatory T cell activation. GO:0002462 tolerance induction to nonself antigen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002462 Tolerance induction in response to nonself antigens. CHEBI:65352 achromobactin free acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65352 CHEBI:90318 EC 6.4.1.1 (pyruvate carboxylase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90318 CHEBI:90310 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-monoacyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90310 GO:0051401 CH domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051401 calponin homology domain binding Interacting selectively and non-covalently with the calponin homology domain of a protein, a domain of 100 residues that occurs in signaling and cytoskeletal proteins. GO:0002478 antigen processing and presentation of exogenous peptide antigen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002478 exogenous peptide antigen processing and presentation The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. GO:0051402 neuron apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051402 apoptosis of neurons|programmed cell death of neuronal cells by apoptosis|programmed cell death of neurons by apoptosis|programmed cell death, neurons|neuronal cell programmed cell death by apoptosis|neuronal cell apoptosis|programmed cell death, neuronal cells|apoptosis of neuronal cells|neuron apoptosis|neuron programmed cell death by apoptosis Any apoptotic process in a neuron, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system. GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002479 exogenous peptide antigen processing and presentation via MHC class I, TAP-dependent|cross-presentation|TAP-dependent exogenous peptide antigen processing and presentation via MHC class I|TAP-dependent antigen processing and presentation of exogenous peptide antigen via MHC class I|cross presentation The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class I molecule. Class I here refers to classical class I molecules. GO:0051400 BH domain binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0051400 Bcl-2 homology domain binding Interacting selectively and non-covalently with the Bcl-2 homology (BH) domain of a protein. Bcl-2-related proteins share homology in one to four conserved regions designated the Bcl-2 homology (BH) domains BH1, BH2, BH3 and BH4. These domains contribute at multiple levels to the function of these proteins in cell death and survival. Anti-apoptotic members of the Bcl-2 family have four BH domains (BH1-BH4). Pro-apoptotic members have fewer BH domains. GO:0051405 obsolete microbial collagenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051405 collagenase MMP-1|matirx metalloproteinase-18|collagenase 1 activity|microbial collagenase activity|matrix metalloproteinase-8|kollaza|metallocollagenase activity|Clostridium histolyticum proteinase A|aspergillopeptidase C|clostridiopeptidase A activity|matrix metalloproteinase-1|metalloproteinase-1|azocollase activity|soycollagestin|clostridiopeptidase I|collagenase A activity|Achromobacter iophagus collagenase|collagen protease activity|collagen peptidase activity|nucleolysin|Clostridium histolyticum collagenase activity|collagenase I activity|clostridiopeptidase II OBSOLETE. Catalysis of the digestion of native collagen in the triple helical region at Xaa-Gly bonds. GO:0002474 antigen processing and presentation of peptide antigen via MHC class I biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002474 peptide antigen processing and presentation via MHC class I The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules. GO:0002475 antigen processing and presentation via MHC class Ib biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002475 The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families. GO:0051406 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051406 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002476 endogenous peptide antigen processing and presentation via MHC class Ib The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family. GO:0051403 stress-activated MAPK cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051403 SAPK cascade|p38 cascade|MAPK14 cascade|stress-activated MAPKKK signaling pathway|stress-activated MAPK signaling pathway|MAPK13 cascade|p38 MAPK signaling|MAPK12 cascade|MAPK11 cascade|stress-activated MAPK signalling pathway|stress-activated MAPKKK signalling pathway|stress-activated MAPKKK cascade|p38 MAPK signalling A series of molecular signals in which a stress-activated MAP kinase cascade relays one or more of the signals; MAP kinase cascades involve at least three protein kinase activities and culminate in the phosphorylation and activation of a MAP kinase. GO:0051404 obsolete clostripain activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051404 alpha-clostridipain|clostripain activity|clostridiopeptidase B activity|Clostridium histolyticum proteinase B OBSOLETE. Catalysis of the cleavage of Arg-Xaa bonds. GO:0002477 antigen processing and presentation of exogenous peptide antigen via MHC class Ib biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002477 exogenous peptide antigen processing and presentation via MHC class Ib The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family. GO:0051409 response to nitrosative stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051409 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions. GO:0002470 plasmacytoid dendritic cell antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002470 The process in which a plasmacytoid dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. GO:0002471 monocyte antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002471 The process in which a monocyte expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. GO:0002472 macrophage antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002472 The process in which a macrophage expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. GO:0051407 glycerone phosphate:inorganic phosphate antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051407 dihydroxyacetone-phosphate:inorganic phosphate antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycerone phosphate(out) + phosphate(in) = glycerone phosphate(in) + phosphate(out). GO:0051408 glyceraldehyde 3-phosphate:inorganic phosphate antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051408 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glyceraldehyde 3-phosphate(out) + phosphate(in) = glyceraldehyde 3-phosphate(in) + phosphate(out). GO:0002473 non-professional antigen presenting cell antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002473 The process in which a non-professional antigen presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. Non-professional antigen presenting cells include all cell types but dendritic cells, B cells, T cells, monocytes, macrophages, and neutrophils. CHEBI:80992 thiohydroximic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_80992 CHEBI:90307 beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90307 GO:0051412 response to corticosterone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051412 response to corticosterone stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosterone stimulus. Corticosterone is a 21 carbon steroid hormone of the corticosteroid type, produced in the cortex of the adrenal glands. In many species, corticosterone is the principal glucocorticoid, involved in regulation of fuel metabolism, immune reactions, and stress responses. GO:0002445 type II hypersensitivity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002445 Wikipedia:Type_II_hypersensitivity An inflammatory response resulting in cell death or dysfunction mediated by activation of the classical complement pathway or induction of effector cell phagocytosis, cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell, or mediated by the direct binding of antibody to cellular receptors. GO:0051413 response to cortisone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051413 response to cortisone stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisone stimulus. Cortisone is a natural glucocorticoid steroid hormone that is metabolically convertible to cortisol. Cortisone is synthesized from cholesterol in the cortex of the adrenal gland under the stimulation of adrenocorticotropin hormone (ACTH). The main physiological effect of cortisone is on carbohydrate metabolism; it can stimulate increased glucose release from the liver, increased liver glycogen synthesis, and decreased utilization of glucose by the tissues. GO:0002446 neutrophil mediated immunity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002446 Any process involved in the carrying out of an immune response by a neutrophil. GO:0051410 detoxification of nitrogen compound biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051410 detoxification of nitrogenous compound|nitric oxide (NO) detoxification Any process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances. GO:0002447 eosinophil mediated immunity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002447 Any process involved in the carrying out of an immune response by an eosinophil. GO:0051411 obsolete ALP binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051411 actinin-associated LIM protein binding|ALP binding OBSOLETE. Interacting selectively and non-covalently wih ALP, actinin-associated LIM protein of the Z band. ALP is a PDZ/LIM domain protein found in the Z band. GO:0002448 mast cell mediated immunity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002448 Any process involved in the carrying out of an immune response by a mast cell. GO:0002441 histamine secretion involved in inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002441 histamine secretion involved in acute inflammatory response The regulated release of histamine by a cell as part of an inflammatory response. GO:0051416 obsolete myotilin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051416 myotilin binding OBSOLETE. Interacting selectively and non-covalently with myotilin, a structural component of the Z-discs in human skeletal and cardiac muscle. Its C-terminus contains two immunoglobulin-like domains and the unique N-terminal half has a serine-rich region, with numerous potential phosphorylation sites, and a stretch of hydrophobic amino acids. Myotilin forms homodimers and binds to alpha-actinin, F-actin, and filamin C. GO:0051417 microtubule nucleation by spindle pole body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051417 microtubule nucleation by SPB|spindle pole body-mediated microtubule nucleation|SPB-mediated microtubule nucleation The 'de novo' formation of a microtubule, mediated by the spindle pole body. GO:0002442 serotonin secretion involved in inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002442 serotonin secretion involved in acute inflammatory response|serotonin release involved in inflammatory response The regulated release of serotonin by a cell as part of an inflammatory response. GO:0002443 leukocyte mediated immunity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002443 immune cell mediated immunity|cell-mediated immune response|leucocyte immune effector process|leucocyte mediated immunity|leukocyte immune effector process|immune cell effector process|cellular immune response Any process involved in the carrying out of an immune response by a leukocyte. GO:0051414 response to cortisol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051414 response to cortisol stimulus|response to hydrocortisone stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisol stimulus. Cortisol is the major natural glucocorticoid synthesized in the zona fasciculata of the adrenal cortex; it affects the metabolism of glucose, protein, and fats and has appreciable mineralocorticoid activity. It also regulates the immune system and affects many other functions. GO:0051415 microtubule nucleation by interphase microtubule organizing center biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051415 interphase microtubule organizing center-mediated microtubule nucleation during interphase|IMTOC-mediated microtubule nucleation during interphase|microtubule nucleation during interphase by IMTOC|interphase microtubule nucleation by interphase microtubule organizing center|interphase microtubule nucleation by interphase microtubule organising centre|microtubule nucleation during interphase by interphase microtubule organizing center The 'de novo' formation of a microtubule by the interphase microtubule organizing center during interphase, the stage of cell cycle between successive rounds of chromosome segregation. GO:0002444 myeloid leukocyte mediated immunity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002444 myeloid leukocyte immune effector process|myeloid leucocyte immune effector process|myeloid leucocyte mediated immunity Any process involved in the carrying out of an immune response by a myeloid leukocyte. GO:0051418 microtubule nucleation by microtubule organizing center biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051418 microtubule nucleation by MTOC|MTOC-mediated microtubule nucleation|microtubule nucleation by microtubule organising centre|microtubule organizing center-mediated microtubule nucleation The 'de novo' formation of a microtubule, mediated by the microtubule organizing center. GO:0051419 obsolete nebulin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051419 nebulin binding OBSOLETE. Interacting selectively and non-covalently with nebulin, a large protein (approximately 800kD) that is anchored at the Z-disc by its C-terminal region and spans the length of the thin filament, ending at the edge of the H-zone. GO:0002440 production of molecular mediator of immune response biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0002440 production of cellular mediator of immune response The synthesis or release of any molecular mediator of the immune response, resulting in an increase in its intracellular or extracellular levels. CHEBI:90337 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-1,2-didodecanoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90337 CHEBI:90339 alpha-N-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90339 CHEBI:90335 alpha-N-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90335 CHEBI:90336 alpha-N-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90336 GO:0002449 lymphocyte mediated immunity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002449 cellular immune response|cell-mediated immunity Any process involved in the carrying out of an immune response by a lymphocyte. GO:0051423 positive regulation of endo-1,4-beta-xylanase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051423 up-regulation of endo-1,4-beta-xylanase activity|endo-1,4-beta-xylanase activator|upregulation of endo-1,4-beta-xylanase activity|up regulation of endo-1,4-beta-xylanase activity|activation of endo-1,4-beta-xylanase activity|xylanase activator|stimulation of endo-1,4-beta-xylanase activity Any process that activates or increases the frequency, rate or extent of endo-(1->4)-beta-xylanase activity, the catalysis of the endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans. GO:0002456 T cell mediated immunity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002456 cell-mediated immunity|T lymphocyte mediated immunity|cellular immune response|T-cell mediated immunity|T-lymphocyte mediated immunity Any process involved in the carrying out of an immune response by a T cell. GO:0051424 corticotropin-releasing hormone binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051424 CRH binding|corticoliberin binding|corticotropin-releasing factor binding|CRF binding Interacting selectively and non-covalently with corticotropin-releasing hormone, a polypeptide hormone involved in the stress response. It is released by the hypothalamus and stimulates the release of corticotropin by the anterior pituitary gland. GO:0002457 T cell antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002457 T lymphocyte antigen processing and presentation|T-cell antigen processing and presentation|T-lymphocyte antigen processing and presentation The process in which a T cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. GO:0002458 peripheral T cell tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002458 peripheral T-cell tolerance induction|peripheral T-lymphocyte tolerance induction|peripheral T lymphocyte tolerance induction Tolerance induction of T cells in the periphery, in this case, any location in the body other than the thymus. GO:0051421 regulation of endo-1,4-beta-xylanase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051421 xylanase regulator|endo-1,4-beta-xylanase regulator Any process that modulates the frequency, rate or extent of endo-(1->4)-beta-xylanase activity, the catalysis of the endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans. GO:0002459 adaptive immune response based on somatic recombination of immune receptors built from leucine-rich repeat domains biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002459 adaptive immune response in jawless fish|adaptive immune response based on somatic recombination of variable lymphocyte receptors built from leucine-rich repeat domains|adaptive immune response based on somatic recombination of VLR built from LRR domains An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of variable lymphocyte receptors (VLR) incorporating leucine-rich repeat (LRR) domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory). Examples of this process are found in jawless fish, including the lampreys (Petromyzontidae) and hagfishes (Myxinidae). GO:0051422 negative regulation of endo-1,4-beta-xylanase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051422 xylanase inhibitor|inhibition of endo-1,4-beta-xylanase activity|down regulation of endo-1,4-beta-xylanase activity|endo-1,4-beta-xylanase inhibitor|downregulation of endo-1,4-beta-xylanase activity|down-regulation of endo-1,4-beta-xylanase activity Any process that stops or reduces the rate of endo-(1->4)-beta-xylanase activity, the catalysis of the endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans. GO:0002452 B cell receptor editing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002452 B-lymphocyte receptor editing|B-cell receptor editing|B lymphocyte receptor editing The process of replacing receptors on B cells, in which RAG gene expression allows continued light-chain gene rearrangement and expression of a new light change which combines with the previous heavy chain to form a new receptor. GO:0051427 hormone receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051427 Interacting selectively and non-covalently with a receptor for hormones. GO:0002453 peripheral B cell anergy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002453 peripheral B lymphocyte anergy|peripheral B-lymphocyte anergy|peripheral B-cell anergy Any process contributing to anergy, a state of functional inactivation that occurs as part of tolerance induction, in peripheral B cells. GO:0051428 peptide hormone receptor binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0051428 polypeptide hormone receptor binding Interacting selectively and non-covalently with a receptor for peptide hormones. GO:0002454 peripheral B cell deletion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002454 peripheral B lymphocyte deletion|peripheral B-lymphocyte deletion|peripheral B-cell deletion The deletion of B cells by apoptotic process occurring as part of peripheral tolerance induction and B cell selection. GO:0051425 PTB domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051425 phosphotyrosine-interacting domain binding|PID binding Interacting selectively and non-covalently with a phosphotyrosine-binding (PTB) domain of a protein. GO:0002455 humoral immune response mediated by circulating immunoglobulin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002455 circulating immunoglobulin mediated immune response|circulating antibody mediated immune response|humoral defence mechanism|humoral immune response mediated by circulating antibody An immune response dependent upon secreted immunoglobulin. An example of this process is found in Mus musculus. GO:0051426 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0051426 GO:0051429 corticotropin-releasing hormone receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051429 corticotropin-releasing factor receptor binding|corticotropin releasing factor receptor binding|CRF receptor binding|CRH receptor binding|corticotropin releasing factor receptor ligand|CRHR binding Interacting selectively and non-covalently with a receptor for corticotropin-releasing hormone (CRH), a polypeptide hormone involved in the stress response. It is released by the hypothalamus and stimulates the release of corticotropin by the anterior pituitary gland. GO:0002450 B cell antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002450 B-cell antigen processing and presentation|B-lymphocyte antigen processing and presentation|B lymphocyte antigen processing and presentation The process in which a B cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. GO:0002451 peripheral B cell tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002451 peripheral B-cell tolerance induction|peripheral B-lymphocyte tolerance induction|peripheral B lymphocyte tolerance induction Tolerance induction of mature B cells in the peripheral lymphoid tissues: the blood, lymph nodes, spleen, and mucosal-associated lymphoid tissue. CHEBI:326268 1,4-butanediammonium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_326268 GO:0051420 obsolete nebulette binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051420 nebulette binding OBSOLETE. Interacting selectively and non-covalently with nebulette, a 107 kDa protein associated with the I-Z-I complex of cardiac myofibrils. It shows a high degree of homology with skeletal muscle nebulin. GO:0002423 natural killer cell mediated immune response to tumor cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002423 An immune response mediated by a natural killer cell triggered in response to the presence of a tumor cell. GO:0051434 BH3 domain binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0051434 Interacting selectively and non-covalently with the BH3 domain of a protein of the Bcl-2 family. The BH3 domain is a potent death domain and has an important role in protein-protein interactions and in cell death. CHEBI:16380 vindoline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16380 GO:0002424 T cell mediated immune response to tumor cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002424 An immune response mediated by a T cell triggered in response to the presence of a tumor cell. GO:0051435 BH4 domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051435 Interacting selectively and non-covalently with the BH4 domain of a protein of the Bcl-2 family. All anti-apoptotic proteins contain BH1 and BH2 domains; some also contain an additional N-terminal BH4 domain, which is almost never seen in pro-apoptotic proteins. Loss of the BH4 domain can diminish or abrogate anti-apoptotic function or even impart outright death-promoting properties to the protein. CHEBI:16381 2'-deoxyribonucleoside 5'-triphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16381 GO:0002425 tolerance induction in urogenital tract biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002425 Tolerance induction taking place in the urogenital tract. GO:0051432 BH1 domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051432 Interacting selectively and non-covalently with the BH1 domain of a protein of the Bcl-2 family. Proteins that act as inhibitors of apoptosis harbour at least three BH domains: BH1, BH2 and BH3; the BH1 and BH2 domains are found in all death antagonists of the Bcl-2 family but only in one class of death agonists. GO:0002426 immunoglobulin production in mucosal tissue biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0002426 antibody production in mucosal tissue The synthesis and release of immunoglobulin in the mucosal tissue. GO:0051433 BH2 domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051433 Interacting selectively and non-covalently with the BH2 domain of a protein of the Bcl-2 family. Proteins that act as inhibitors of apoptosis harbour at least three BH domains: BH1, BH2 and BH3; the BH1 and BH2 domains are found in all death antagonists of the Bcl-2 family but only in one class of death agonists. GO:0051438 regulation of ubiquitin-protein transferase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051438 regulation of ubiquitin transferase activity|anaphase-promoting complex regulator|SCF complex regulator|ubiquitin-protein transferase regulator|APC regulator|ubiquitin transferase regulator Any process that modulates the frequency, rate or extent of ubiquitin transferase activity. GO:0051439 obsolete regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051439 regulation of ubiquitin ligase activity during mitotic cell cycle|mitotic APC regulator|regulation of ubiquitin-protein ligase activity during mitotic cell cycle|mitotic ubiquitin-protein ligase regulator|mitotic SCF complex regulator|mitotic ubiquitin ligase regulator|mitotic anaphase-promoting complex regulator OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of ubiquitin ligase activity that contributes to the mitotic cell cycle. GO:0002420 natural killer cell mediated cytotoxicity directed against tumor cell target biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002420 NK cell mediated cytotoxicity directed against tumor cell target The directed killing of a tumor cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors. GO:0051436 obsolete negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051436 mitotic ubiquitin ligase inhibitor|down regulation of ubiquitin ligase activity during mitotic cell cycle|anaphase-promoting complex inhibition during mitotic cell cycle|downregulation of ubiquitin ligase activity during mitotic cell cycle|mitotic anaphase promoting complex inhibitor|mitotic SCF complex inhibitor|mitotic anaphase promoting complex inhibition|negative regulation of ubiquitin ligase activity during mitotic cell cycle|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle|down-regulation of ubiquitin ligase activity during mitotic cell cycle|anaphase promoting complex inhibition during mitotic cell cycle|APC inhibition during mitotic cell cycle|inhibition of ubiquitin ligase activity during mitotic cell cycle|mitotic anaphase-promoting complex inhibitor|mitotic APC inhibition|mitotic APC inhibitor|mitotic anaphase-promoting complex inhibition OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin ligase activity that contributes to the mitotic cell cycle. GO:0002421 B cell antigen processing and presentation following pinocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002421 B lymphocyte antigen processing and presentation following pinocytosis|B-cell antigen processing and presentation following pinocytosis|B-lymphocyte antigen processing and presentation following pinocytosis B cell antigen processing and presentation which is initiated by uptake of antigen via pinocytosis. GO:0051437 obsolete positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051437 upregulation of ubiquitin ligase activity during mitotic cell cycle|activation of ubiquitin ligase activity during mitotic cell cycle|positive regulation of ubiquitin ligase activity during mitotic cell cycle|stimulation of ubiquitin ligase activity during mitotic cell cycle|positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle|up regulation of ubiquitin ligase activity during mitotic cell cycle|mitotic ubiquitin ligase activator|up-regulation of ubiquitin ligase activity during mitotic cell cycle|mitotic SCF complex activator OBSOLETE. Any process that activates, maintains or increases the rate of ubiquitin ligase activity that contributes to the regulation of the mitotic cell cycle phase transition. GO:0002422 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0002422 GO:2000665 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2000665 GO:2000666 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2000666 GO:2000667 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2000667 GO:2000668 regulation of dendritic cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000668 regulation of dendritic cell apoptosis Any process that modulates the frequency, rate or extent of dendritic cell apoptotic process. GO:2000669 negative regulation of dendritic cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000669 negative regulation of dendritic cell apoptosis Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell apoptotic process. GO:1905600 regulation of receptor-mediated endocytosis involved in cholesterol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905600 regulation of receptor-mediated endocytosis of LDL|regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport|regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport Any process that modulates the frequency, rate or extent of receptor-mediated endocytosis involved in cholesterol transport. GO:1905601 negative regulation of receptor-mediated endocytosis involved in cholesterol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905601 down-regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|negative regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|down-regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|negative regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|downregulation of receptor-mediated endocytosis of LDL|inhibition of receptor-mediated endocytosis of LDL|down regulation of receptor-mediated endocytosis of LDL|down regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport|down regulation of receptor-mediated endocytosis involved in cholesterol transport|downregulation of receptor-mediated endocytosis involved in intracellular cholesterol transport|downregulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|downregulation of receptor-mediated endocytosis involved in cholesterol transport|inhibition of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|down regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|down-regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport|negative regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport|down regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|inhibition of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|down-regulation of receptor-mediated endocytosis involved in cholesterol transport|down-regulation of receptor-mediated endocytosis of LDL|negative regulation of receptor-mediated endocytosis of LDL|downregulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|inhibition of receptor-mediated endocytosis involved in cholesterol transport|inhibition of receptor-mediated endocytosis involved in intracellular cholesterol transport Any process that stops, prevents or reduces the frequency, rate or extent of receptor-mediated endocytosis involved in cholesterol transport. GO:2000660 negative regulation of interleukin-1-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000660 negative regulation of interleukin-1 alpha-mediated signaling pathway|negative regulation of interleukin-1-mediated signalling pathway|negative regulation of interleukin-1 beta-mediated signaling pathway|negative regulation of IL-1-mediated signaling pathway|negative regulation of IL-1 alpha-mediated signaling pathway|negative regulation of IL-1 beta-mediated signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-1-mediated signaling pathway. GO:1905602 positive regulation of receptor-mediated endocytosis involved in cholesterol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905602 activation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|upregulation of receptor-mediated endocytosis involved in intracellular cholesterol transport|positive regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|upregulation of receptor-mediated endocytosis involved in cholesterol transport|up regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|upregulation of receptor-mediated endocytosis of LDL|up-regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|up regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport|activation of receptor-mediated endocytosis of LDL|positive regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport|up regulation of receptor-mediated endocytosis involved in cholesterol transport|upregulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|up-regulation of receptor-mediated endocytosis of LDL|upregulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|activation of receptor-mediated endocytosis involved in cholesterol transport|activation of receptor-mediated endocytosis involved in intracellular cholesterol transport|up-regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport|up-regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|up regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|up-regulation of receptor-mediated endocytosis involved in cholesterol transport|positive regulation of receptor-mediated endocytosis of LDL|positive regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|up regulation of receptor-mediated endocytosis of LDL|activation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport Any process that activates or increases the frequency, rate or extent of receptor-mediated endocytosis involved in cholesterol transport. GO:2000661 positive regulation of interleukin-1-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000661 positive regulation of interleukin-1-mediated signalling pathway|positive regulation of interleukin-1 beta-mediated signaling pathway|positive regulation of interleukin-1 alpha-mediated signaling pathway|positive regulation of IL-1-mediated signaling pathway|positive regulation of IL-1 alpha-mediated signaling pathway|positive regulation of IL-1 beta-mediated signaling pathway Any process that activates or increases the frequency, rate or extent of interleukin-1-mediated signaling pathway. CHEBI:90359 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-monododecanoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90359 UBERON:0008307 heart endothelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0008307 cardiac endothelium An endothelium that is part of a heart [Automatically generated definition]. GO:1905603 regulation of blood-brain barrier permeability biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905603 regulation of blood/brain barrier permeability|regulation of BBB permeability Any process that modulates blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain. GO:2000662 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2000662 GO:1905604 negative regulation of blood-brain barrier permeability biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905604 downregulation of blood/brain barrier permeability|negative regulation of BBB permeability|down-regulation of BBB permeability|downregulation of blood-brain barrier permeability|inhibition of maintenance of permeability of BBB|downregulation of BBB permeability|inhibition of maintenance of permeability of blood-brain barrier|down-regulation of blood/brain barrier permeability|negative regulation of blood/brain barrier permeability|down-regulation of blood-brain barrier permeability Any process that decreases blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain. GO:2000663 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2000663 CHEBI:16379 Co-methyl-Co-5-hydroxybenzimidazolylcob(III)amide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16379 GO:1905605 positive regulation of blood-brain barrier permeability biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905605 activation of maintenance of permeability of blood-brain barrier|positive regulation of BBB permeability|upregulation of blood/brain barrier permeability|upregulation of blood-brain barrier permeability|up-regulation of blood/brain barrier permeability|upregulation of BBB permeability|up-regulation of blood-brain barrier permeability|activation of maintenance of permeability of BBB|up-regulation of BBB permeability|positive regulation of blood/brain barrier permeability Any process that increases blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain. GO:2000664 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2000664 GO:1905606 regulation of presynapse assembly biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_1905606 regulation of presynaptic terminal assembly|regulation of presynapse biogenesis Any process that modulates the frequency, rate or extent of presynapse assembly. CHEBI:16377 sabinene hydrate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16377 GO:1905607 negative regulation of presynapse assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905607 down-regulation of presynaptic terminal assembly|negative regulation of presynaptic terminal assembly|downregulation of presynapse biogenesis|down-regulation of presynapse assembly|inhibition of presynaptic terminal assembly|inhibition of presynapse assembly|negative regulation of presynapse biogenesis|down-regulation of presynapse biogenesis|inhibition of presynapse biogenesis|down regulation of presynaptic terminal assembly|downregulation of presynaptic terminal assembly|down regulation of presynapse assembly|downregulation of presynapse assembly|down regulation of presynapse biogenesis Any process that stops, prevents or reduces the frequency, rate or extent of presynapse assembly. CHEBI:16378 threo-3-methyl-L-aspartate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16378 CHEBI:90356 dibenzothiophene sulfone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90356 GO:1905608 positive regulation of presynapse assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905608 activation of presynapse assembly|up regulation of presynapse biogenesis|activation of presynapse biogenesis|positive regulation of presynapse biogenesis|up-regulation of presynaptic terminal assembly|up-regulation of presynapse assembly|upregulation of presynaptic terminal assembly|up-regulation of presynapse biogenesis|upregulation of presynapse assembly|up regulation of presynaptic terminal assembly|upregulation of presynapse biogenesis|activation of presynaptic terminal assembly|positive regulation of presynaptic terminal assembly|up regulation of presynapse assembly Any process that activates or increases the frequency, rate or extent of presynapse assembly. CHEBI:16375 D-cysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16375 CHEBI:90357 beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-Cer biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90357 GO:1905609 positive regulation of smooth muscle cell-matrix adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905609 up regulation of smooth muscle cell-matrix adhesion|upregulation of smooth muscle cell-matrix adhesion|activation of smooth muscle cell-matrix adhesion|up-regulation of smooth muscle cell-matrix adhesion Any process that activates or increases the frequency, rate or extent of smooth muscle cell-matrix adhesion. CHEBI:90358 beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-Cer biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90358 GO:0051430 corticotropin-releasing hormone receptor 1 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051430 type 1 corticotropin-releasing factor receptor binding|type 1 corticotropin releasing factor receptor binding|type 1 corticotropin releasing factor receptor ligand|CRHR1 binding Interacting selectively and non-covalently with the corticotropin-releasing hormone receptor 1 (CRHR1). CRHR1 is the major subtype in the pituitary corticotroph, and mediates the stimulatory actions of corticotropin-releasing hormone on corticotropin hormone secretion. CRHR1 are also located in cortical areas of the brain, cerebellum and limbic system. GO:0002427 mucosal tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002427 Tolerance induction taking place in the mucosal tissues. CHEBI:16373 (S)-3-(imidazol-5-yl)lactic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16373 GO:0002428 antigen processing and presentation of peptide antigen via MHC class Ib biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002428 peptide antigen processing and presentation via MHC class Ib The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC class Ib protein complex on its cell surface. The peptide antigen may originate from an endogenous or exogenous protein. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E family. GO:0051431 corticotropin-releasing hormone receptor 2 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051431 type 2 corticotropin-releasing factor receptor binding|type 2 corticotropin releasing factor receptor binding|type 2 corticotropin releasing factor receptor ligand|CRHR2 binding Interacting selectively and non-covalently with the corticotropin-releasing hormone receptor type 2 (CRHR2). The CRHR2 has several splice variants that are located in sub-cortical areas of the brain and in the periphery. CHEBI:16374 menaquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16374 GO:0002429 immune response-activating cell surface receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002429 immune response-activating cell surface receptor signalling pathway|activation of immune response by cell surface receptor signaling pathway A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a cell capable of activating or perpetuating an immune response. CHEBI:16372 4,5alpha-dihydrocortisone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16372 GO:0002434 immune complex clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002434 A process directed at removing immune complexes from the body. Immune complexes are clusters of antibodies bound to antigen, to which complement may also be fixed, and which may precipitate or remain in solution. GO:0051445 regulation of meiotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051445 modulation of meiotic cell cycle progression|regulation of progression through meiotic cell cycle|meiotic cell cycle regulator|meiotic cell cycle regulation|regulation of meiotic cell cycle progression|meiotic cell cycle modulation Any process that modulates the rate or extent of progression through the meiotic cell cycle. PR:000013164 pancreatic prohormone biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000013164 PP|obinepitide|PPY|PNP|pancreatic polypeptide A protein that is a translation product of the human PPY gene or a 1:1 ortholog thereof. GO:0002435 immune complex clearance by erythrocytes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002435 Wikipedia:Immune_complex immune complex clearance by RBCs|immune complex clearance by red blood cells The process of immune complex clearance by erythrocytes. The process often starts with binding of complement receptor 1 (CR1) on the surface of erythrocytes to a complement coated immune complex. The complex bound to erythrocyte CR1 is then transported to the liver or spleen where it is presented to phagocytes. The process ends when the complex is removed from CR1, allowing the erythrocyte to return to general circulation. GO:0051446 positive regulation of meiotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051446 stimulation of progression through meiotic cell cycle|positive regulation of progression through meiotic cell cycle|up-regulation of progression through meiotic cell cycle|activation of progression through meiotic cell cycle|up regulation of progression through meiotic cell cycle|positive regulation of meiotic cell cycle progression|upregulation of progression through meiotic cell cycle Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle. CHEBI:16370 dihydrophloroglucinol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16370 GO:0051443 positive regulation of ubiquitin-protein transferase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051443 stimulation of ubiquitin transferase activity|up-regulation of ubiquitin transferase activity|activation of ubiquitin transferase activity|up regulation of ubiquitin ligase activity|positive regulation of ubiquitin transferase activity|ubiquitin transferase activator|anaphase promoting complex activator|APC activator|APC activation|upregulation of ubiquitin transferase activity|anaphase-promoting complex activator|SCF complex activator Any process that activates, maintains or increases the rate of ubiquitin transferase activity. GO:0002436 immune complex clearance by monocytes and macrophages biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002436 The process of immune complex clearance by monocytes or macrophages. GO:0051444 negative regulation of ubiquitin-protein transferase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051444 anaphase-promoting complex inhibition|negative regulation of ubiquitin transferase activity|anaphase-promoting complex inhibitor|SCF complex inhibitor|down-regulation of ubiquitin transferase activity|APC inhibition|anaphase promoting complex inhibition|downregulation of ubiquitin transferase activity|down regulation of ubiquitin transferase activity|ubiquitin transferase inhibitor|inhibition of ubiquitin transferase activity|APC inhibitor|anaphase promoting complex inhibitor Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin transferase activity. GO:0002437 inflammatory response to antigenic stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002437 An inflammatory response to an antigenic stimulus, which can be include any number of T cell or B cell epitopes. GO:0002430 complement receptor mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002430 complement receptor mediated signalling pathway|immune response-regulating cell surface receptor signalling pathway A series of molecular signals generated as a consequence of a component of the complement pathway binding to a complement receptor. Such components include both whole complement proteins and fragments of complement proteins generated through the activity of the complement pathway. GO:0051449 thyrotropin-releasing hormone binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051449 thyrotropin releasing hormone binding Interacting selectively and non-covalently with thyrotropin-releasing hormone, a tripeptide hormone that stimulates the release of thyroid-stimulating hormone (TSH) and prolactin by the anterior pituitary and it is produced by the hypothalamus and travels across the median eminence to the pituitary via the pituitary portal system. GO:0002431 Fc receptor mediated stimulatory signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002431 Fc-receptor mediated stimulatory signaling pathway|Fc receptor mediated stimulatory signalling pathway A series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of activating or perpetuating an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region. GO:0051447 negative regulation of meiotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051447 negative regulation of progression through meiotic cell cycle|down-regulation of progression through meiotic cell cycle|negative regulation of meiotic cell cycle progression|downregulation of progression through meiotic cell cycle|down regulation of progression through meiotic cell cycle|inhibition of progression through meiotic cell cycle Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle. GO:0002432 granuloma formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002432 The formation of nodular inflammatory lesions, usually small or granular, firm, persistent, well-structured, and containing compactly grouped T lymphocytes and modified phagocytes such as epithelioid cells, giant cells, and other macrophages. Granuloma formation represents a chronic inflammatory response initiated by various infectious and noninfectious agents. The center of a granuloma consists of fused macrophages, which can become necrotic. GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002433 phagocytosis triggered by activation of immune response cell surface activating receptor|immune response-regulating cell surface receptor signalling pathway involved in phagocytosis An immune response-regulating cell surface receptor signaling pathway that contributes to the endocytic engulfment of external particulate material by phagocytes. GO:0051448 gonadotropin-releasing hormone binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0051448 gonadotrophin releasing hormone binding|GnRH binding Interacting selectively and non-covalently with gonadotropin-releasing hormone (GnRH), a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus. GO:2000676 positive regulation of type B pancreatic cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000676 positive regulation of pancreatic B cell apoptosis|positive regulation of type B pancreatic cell apoptosis|positive regulation of pancreatic beta cell apoptosis Any process that activates or increases the frequency, rate or extent of type B pancreatic cell apoptotic process. GO:2000677 regulation of transcription regulatory region DNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000677 Any process that modulates the frequency, rate or extent of transcription regulatory region DNA binding. GO:2000678 negative regulation of transcription regulatory region DNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000678 Any process that stops, prevents or reduces the frequency, rate or extent of transcription regulatory region DNA binding. GO:2000679 positive regulation of transcription regulatory region DNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000679 Any process that activates or increases the frequency, rate or extent of transcription regulatory region DNA binding. GO:1905610 regulation of mRNA cap binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905610 Any process that modulates the frequency, rate or extent of mRNA cap binding. GO:1905611 negative regulation of mRNA cap binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905611 down-regulation of mRNA cap binding|downregulation of mRNA cap binding|down regulation of mRNA cap binding|inhibition of mRNA cap binding Any process that stops, prevents or reduces the frequency, rate or extent of mRNA cap binding. GO:2000670 positive regulation of dendritic cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000670 positive regulation of dendritic cell apoptosis Any process that activates or increases the frequency, rate or extent of dendritic cell apoptotic process. GO:2000671 regulation of motor neuron apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000671 regulation of motoneuron apoptosis|regulation of motor neuron apoptosis Any process that modulates the frequency, rate or extent of motor neuron apoptotic process. GO:1905612 positive regulation of mRNA cap binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905612 up regulation of mRNA cap binding|upregulation of mRNA cap binding|up-regulation of mRNA cap binding|activation of mRNA cap binding Any process that activates or increases the frequency, rate or extent of mRNA cap binding. GO:2000672 negative regulation of motor neuron apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000672 negative regulation of motor neuron apoptosis|negative regulation of motoneuron apoptosis Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron apoptotic process. GO:1905613 regulation of developmental vegetative growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905613 Any process that modulates the frequency, rate or extent of developmental vegetative growth. GO:1905614 negative regulation of developmental vegetative growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905614 down-regulation of developmental vegetative growth|inhibition of developmental vegetative growth|down regulation of developmental vegetative growth|downregulation of developmental vegetative growth Any process that stops, prevents or reduces the frequency, rate or extent of developmental vegetative growth. GO:2000673 positive regulation of motor neuron apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000673 positive regulation of motor neuron apoptosis|positive regulation of motoneuron apoptosis Any process that activates or increases the frequency, rate or extent of motor neuron apoptotic process. CHEBI:16368 6-hydroxymellein biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16368 GO:2000674 regulation of type B pancreatic cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000674 regulation of type B pancreatic cell apoptosis|regulation of pancreatic beta cell apoptosis|regulation of pancreatic B cell apoptosis Any process that modulates the frequency, rate or extent of type B pancreatic cell apoptotic process. GO:1905615 positive regulation of developmental vegetative growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905615 up-regulation of developmental vegetative growth|upregulation of developmental vegetative growth|up regulation of developmental vegetative growth|activation of developmental vegetative growth Any process that activates or increases the frequency, rate or extent of developmental vegetative growth. GO:1905616 regulation of miRNA mediated inhibition of translation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905616 regulation of down-regulation of translation involved in gene silencing by miRNA|regulation of miRNA-mediated gene silencing, negative regulation of translation|regulation of inhibition of translation involved in gene silencing by miRNA|regulation of gene silencing by miRNA, negative regulation of translation|regulation of down regulation of translation involved in gene silencing by miRNA|regulation of negative regulation of translation involved in gene silencing by microRNA|regulation of downregulation of translation involved in gene silencing by miRNA Any process that modulates the frequency, rate or extent of miRNA mediated inhibition of translation. GO:2000675 negative regulation of type B pancreatic cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000675 negative regulation of pancreatic B cell apoptosis|negative regulation of type B pancreatic cell apoptosis|negative regulation of pancreatic beta cell apoptosis Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell apoptotic process. CHEBI:16369 5-dehydro-4-deoxy-D-glucaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16369 CHEBI:41336 5-amino-1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazole-4-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_41336 GO:1905617 negative regulation of miRNA mediated inhibition of translation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905617 downregulation of down-regulation of translation involved in gene silencing by miRNA|downregulation of downregulation of translation involved in gene silencing by miRNA|down regulation of miRNA-mediated gene silencing, negative regulation of translation|inhibition of gene silencing by miRNA, negative regulation of translation|down regulation of down-regulation of translation involved in gene silencing by miRNA|inhibition of down-regulation of translation involved in gene silencing by miRNA|negative regulation of negative regulation of translation involved in gene silencing by microRNA|inhibition of inhibition of translation involved in gene silencing by miRNA|down-regulation of negative regulation of translation involved in gene silencing by microRNA|downregulation of miRNA-mediated gene silencing, negative regulation of translation|down-regulation of miRNA mediated inhibition of translation|down-regulation of downregulation of translation involved in gene silencing by miRNA|down-regulation of down regulation of translation involved in gene silencing by miRNA|negative regulation of down regulation of translation involved in gene silencing by miRNA|negative regulation of downregulation of translation involved in gene silencing by miRNA|inhibition of negative regulation of translation involved in gene silencing by microRNA|down regulation of inhibition of translation involved in gene silencing by miRNA|down-regulation of miRNA-mediated gene silencing, negative regulation of translation|negative regulation of miRNA-mediated gene silencing, negative regulation of translation|inhibition of downregulation of translation involved in gene silencing by miRNA|downregulation of inhibition of translation involved in gene silencing by miRNA|down regulation of gene silencing by miRNA, negative regulation of translation|downregulation of miRNA mediated inhibition of translation|downregulation of down regulation of translation involved in gene silencing by miRNA|downregulation of gene silencing by miRNA, negative regulation of translation|down regulation of miRNA mediated inhibition of translation|inhibition of miRNA mediated inhibition of translation|down-regulation of down-regulation of translation involved in gene silencing by miRNA|down regulation of down regulation of translation involved in gene silencing by miRNA|negative regulation of down-regulation of translation involved in gene silencing by miRNA|inhibition of down regulation of translation involved in gene silencing by miRNA|down regulation of negative regulation of translation involved in gene silencing by microRNA|negative regulation of inhibition of translation involved in gene silencing by miRNA|down-regulation of inhibition of translation involved in gene silencing by miRNA|inhibition of miRNA-mediated gene silencing, negative regulation of translation|downregulation of negative regulation of translation involved in gene silencing by microRNA|down-regulation of gene silencing by miRNA, negative regulation of translation|negative regulation of gene silencing by miRNA, negative regulation of translation|down regulation of downregulation of translation involved in gene silencing by miRNA Any process that stops, prevents or reduces the frequency, rate or extent of miRNA mediated inhibition of translation. CHEBI:16366 anthocyanidin cation biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16366 GO:1905618 positive regulation of miRNA mediated inhibition of translation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905618 upregulation of miRNA-mediated gene silencing, negative regulation of translation|up regulation of negative regulation of translation involved in gene silencing by microRNA|up-regulation of miRNA mediated inhibition of translation|activation of negative regulation of translation involved in gene silencing by microRNA|up-regulation of inhibition of translation involved in gene silencing by miRNA|positive regulation of negative regulation of translation involved in gene silencing by microRNA|activation of miRNA mediated inhibition of translation|up-regulation of down regulation of translation involved in gene silencing by miRNA|up-regulation of gene silencing by miRNA, negative regulation of translation|up regulation of downregulation of translation involved in gene silencing by miRNA|activation of down regulation of translation involved in gene silencing by miRNA|positive regulation of downregulation of translation involved in gene silencing by miRNA|activation of downregulation of translation involved in gene silencing by miRNA|upregulation of down-regulation of translation involved in gene silencing by miRNA|up regulation of miRNA-mediated gene silencing, negative regulation of translation|upregulation of inhibition of translation involved in gene silencing by miRNA|positive regulation of miRNA-mediated gene silencing, negative regulation of translation|up-regulation of negative regulation of translation involved in gene silencing by microRNA|upregulation of gene silencing by miRNA, negative regulation of translation|up regulation of miRNA mediated inhibition of translation|positive regulation of down regulation of translation involved in gene silencing by miRNA|up-regulation of down-regulation of translation involved in gene silencing by miRNA|up regulation of down regulation of translation involved in gene silencing by miRNA|activation of miRNA-mediated gene silencing, negative regulation of translation|up-regulation of downregulation of translation involved in gene silencing by miRNA|activation of down-regulation of translation involved in gene silencing by miRNA|up regulation of inhibition of translation involved in gene silencing by miRNA|upregulation of negative regulation of translation involved in gene silencing by microRNA|up-regulation of miRNA-mediated gene silencing, negative regulation of translation|positive regulation of inhibition of translation involved in gene silencing by miRNA|up regulation of gene silencing by miRNA, negative regulation of translation|upregulation of miRNA mediated inhibition of translation|positive regulation of gene silencing by miRNA, negative regulation of translation|activation of gene silencing by miRNA, negative regulation of translation|upregulation of downregulation of translation involved in gene silencing by miRNA|upregulation of down regulation of translation involved in gene silencing by miRNA|positive regulation of down-regulation of translation involved in gene silencing by miRNA|activation of inhibition of translation involved in gene silencing by miRNA|up regulation of down-regulation of translation involved in gene silencing by miRNA Any process that activates or increases the frequency, rate or extent of miRNA mediated inhibition of translation. CHEBI:16367 N(tele)-methyl-L-histidine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16367 GO:1905619 regulation of alpha-(1->3)-fucosyltransferase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905619 regulation of alpha(1,3)-fucosyltransferase activity|regulation of alpha-(1,3)-fucosyltransferase activity|regulation of alpha-1,3-fucosyltransferase activity Any process that modulates the frequency, rate or extent of alpha-(1->3)-fucosyltransferase activity. CHEBI:16364 pyridine-2,5-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16364 CHEBI:16365 quinolin-2-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16365 GO:0051441 obsolete positive regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051441 meiotic anaphase promoting complex activator|meiotic APC activator|upregulation of ubiquitin ligase activity during meiotic cell cycle|activation of ubiquitin ligase activity of anaphase-promoting complex during meiotic cell cycle|activation of anaphase-promoting complex activity involved in meiotic cell cycle|anaphase promoting complex activation during meiotic cell cycle|APC activation during meiotic cell cycle|positive regulation of ubiquitin ligase activity during meiotic cell cycle|activation of ubiquitin ligase activity during meiotic cell cycle|meiotic APC activation|meiotic anaphase-promoting complex activator|stimulation of ubiquitin ligase activity during meiotic cell cycle|up regulation of ubiquitin ligase activity during meiotic cell cycle|meiotic SCF complex activator|positive regulation of ubiquitin-protein ligase activity during meiotic cell cycle|meiotic anaphase promoting complex activation|activation of ubiquitin ligase activity of APC during meiotic cell cycle|activation of ubiquitin ligase activity of anaphase promoting complex during meiotic cell cycle|activation of anaphase-promoting complex activity during meiotic cell cycle|up-regulation of ubiquitin ligase activity during meiotic cell cycle|meiotic ubiquitin ligase activator|anaphase-promoting complex activation during meiotic cell cycle OBSOLETE. Any process that activates, maintains or increases the rate of ubiquitin ligase activity during the meiotic cell cycle. CHEBI:90340 1,2-didodecanoyl-3-beta-D-galactosyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90340 CHEBI:16362 D-aldose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16362 GO:0002438 acute inflammatory response to antigenic stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002438 An acute inflammatory response to an antigenic stimulus. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response. GO:0051442 obsolete negative regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051442 meiotic ubiquitin ligase inhibitor|down regulation of ubiquitin ligase activity during meiotic cell cycle|anaphase-promoting complex inhibition during meiotic cell cycle|downregulation of ubiquitin ligase activity during meiotic cell cycle|meiotic APC inhibitor|meiotic anaphase promoting complex inhibitor|meiotic anaphase-promoting complex inhibition|negative regulation of ubiquitin ligase activity during meiotic cell cycle|down-regulation of ubiquitin ligase activity during meiotic cell cycle|APC inhibition during meiotic cell cycle|anaphase promoting complex inhibition during meiotic cell cycle|inhibition of ubiquitin ligase activity during meiotic cell cycle|meiotic anaphase-promoting complex inhibitor|meiotic SCF complex inhibitor|meiotic APC inhibition|meiotic anaphase promoting complex inhibition OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin ligase activity during the meiotic cell cycle. GO:0002439 chronic inflammatory response to antigenic stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002439 A chronic inflammatory response to an antigenic stimulus. A chronic inflammatory response persists indefinitely during days, weeks, or months in the life of an individual. CHEBI:16363 alpha-santonin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16363 CHEBI:90342 2,3-di-O-dodecanoyl-1-O-beta-D-galactopyranosyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90342 GO:0051440 obsolete regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051440 meiotic anaphase-promoting complex regulator|meiotic SCF complex regulator|regulation of ubiquitin ligase activity during meiotic cell cycle|regulation of ubiquitin-protein ligase activity during meiotic cell cycle|meiotic ubiquitin-protein ligase regulator|meiotic APC regulator|meiotic ubiquitin ligase regulator OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of ubiquitin ligase activity during the meiotic cell cycle. GO:0002401 tolerance induction in mucosal-associated lymphoid tissue biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002401 tolerance induction in MALT Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT). GO:0051456 attachment of spindle microtubules to kinetochore involved in meiotic sister chromatid segregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051456 meiotic bipolar attachment|attachment of spindle microtubules to kinetochore during meiosis II|attachment of spindle microtubules to kinetochore involved in meiosis II The process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex during meiosis II. During meiosis II sister kinetochores are situated facing opposite spindle poles and bipolar attachment of the sister chromosomes to the spindle occurs. GO:0002402 B cell tolerance induction in mucosal-associated lymphoid tissue biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002402 B cell tolerance induction in MALT Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT) mediated by B cells. GO:0051457 maintenance of protein location in nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051457 nuclear protein retention|maintenance of nuclear protein localization|maintenance of protein localization in nucleus|protein sequestration in nucleus|nuclear protein sequestering|nuclear protein sequestration|protein storage in nucleus|protein-nuclear retention|storage of protein in nucleus|maintenance of protein location in cell nucleus|protein retention in nucleus|sequestration of protein in nucleus Any process in which a protein is maintained in the nucleus and prevented from moving elsewhere. These include sequestration within the nucleus, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the nucleus. GO:0002403 T cell tolerance induction in mucosal-associated lymphoid tissue biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002403 T cell tolerance induction in MALT Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT) mediated by T cells. GO:0051454 intracellular pH elevation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051454 intracellular alkalinization|cellular alkalinization|elevation of cellular pH|cell pH elevation|pH elevation in cell Any process that increases the internal pH of a cell, measured by the concentration of the hydrogen ion. GO:0051455 monopolar spindle attachment to meiosis I kinetochore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051455 monopolar attachment|attachment of spindle microtubules to kinetochore involved in meiosis I|attachment of spindle microtubules to kinetochore during meiosis I|sister kinetochore mono-orientation|attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation The process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex during meiosis I. During meiosis I sister kinetochores are lying next to each other facing the same spindle pole and monopolar attachment of the chromatid to the spindle occurs. GO:0002404 antigen sampling in mucosal-associated lymphoid tissue biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002404 antigen sampling in MALT|antigen transport in mucosal-associated lymphoid tissue|antigen transport in MALT The process of apical-to-basolateral delivery of soluble and particulate antigens to underlying mucosal-associated lymphoid tissue. GO:0051458 corticotropin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051458 ACTH secretion|adrenotropic hormone secretion|adrenocorticotropic hormone secretion|corticotropic hormone secretion|adrenotropin secretion|adrenocorticotropin secretion The regulated release of corticotropin by a cell. Corticotropin hormone is a polypeptide hormone synthesized and secreted from corticotropes in the anterior lobe of the pituitary gland in response to corticotropin-releasing hormone (CRH) released by the hypothalamus. GO:0051459 regulation of corticotropin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051459 regulation of adrenotropin hormone secretion|regulation of corticotropic hormone secretion|regulation of adrenocorticotropic hormone secretion|regulation of adrenotropin secretion|regulation of ACTH secretion|regulation of adrenocorticotropin secretion Any process that modulates the frequency, rate or extent of the regulated release of corticotropic hormone from a cell. GO:0002400 tolerance induction in nasopharyngeal-associated lymphoid tissue biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002400 tolerance induction in NALT|nasal tolerance Tolerance induction taking place in the nasopharyngeal-associated lymphoid tissue (NALT). GO:2000687 obsolete negative regulation of rubidium ion transmembrane transporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000687 negative regulation of Rb+ transmembrane transporter activity|negative regulation of rubidium transmembrane transporter activity|negative regulation of rubidium cation transmembrane transporter activity OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of rubidium ion transmembrane transporter activity. GO:2000688 obsolete positive regulation of rubidium ion transmembrane transporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000688 positive regulation of Rb+ transmembrane transporter activity|positive regulation of rubidium transmembrane transporter activity|positive regulation of rubidium cation transmembrane transporter activity OBSOLETE. Any process that activates or increases the frequency, rate or extent of rubidium ion transmembrane transporter activity. CHEBI:31997 N,N-dimethylethanolamine phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31997 GO:2000689 actomyosin contractile ring assembly actin filament organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000689 regulation of actin filament localization of cytokinesis, contractile ring assembly|actin filament organization of cytokinesis, actomyosin contractile ring assembly|regulation of actin filament localization of cytokinesis, actomyosin ring biosynthesis|actin filament organisation of cytokinesis, actomyosin ring formation|actin filament organisation of contractile ring assembly|actin filament organisation of cytokinesis, actomyosin contractile ring assembly|regulation of actin filament localization of cytokinesis, actomyosin contractile ring formation|regulation of actin filament localization of constriction ring assembly|actin filament organization of cytokinesis, actomyosin ring formation|actin filament organization involved in cytokinetic actomyosin contractile ring assembly|actin filament organisation of cytokinesis, contractile ring assembly|actin filament organization of cytokinesis, actomyosin ring biosynthesis|actin filament organisation of cytokinesis, actomyosin contractile ring formation|actin filament organization of cytokinesis, contractile ring assembly|actin filament organisation of constriction ring assembly|regulation of actin filament localization of contractile ring assembly|actin filament organisation of cytokinesis, actomyosin ring biosynthesis|regulation of actin filament localization of cytokinesis, actomyosin ring formation|regulation of actin filament localization of cytokinesis, actomyosin contractile ring assembly|actin filament organization of cytokinesis, actomyosin contractile ring formation|actin filament organization of constriction ring assembly|actin filament organization of contractile ring assembly An actin filament organization process that contributes to actomyosin contractile ring assembly during cytokinesis. CHEBI:31998 N-acylphytosphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_31998 CHEBI:41321 cholesterol sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_41321 GO:1905630 response to glyceraldehyde biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905630 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glyceraldehyde stimulus. GO:1905620 negative regulation of alpha-(1->3)-fucosyltransferase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905620 down-regulation of alpha(1,3)-fucosyltransferase activity|negative regulation of alpha(1,3)-fucosyltransferase activity|down regulation of alpha-(1,3)-fucosyltransferase activity|down regulation of alpha-1,3-fucosyltransferase activity|downregulation of alpha-(1,3)-fucosyltransferase activity|downregulation of alpha-(1->3)-fucosyltransferase activity|downregulation of alpha-1,3-fucosyltransferase activity|downregulation of alpha(1,3)-fucosyltransferase activity|down regulation of alpha-(1->3)-fucosyltransferase activity|inhibition of alpha-(1->3)-fucosyltransferase activity|negative regulation of alpha-(1,3)-fucosyltransferase activity|down regulation of alpha(1,3)-fucosyltransferase activity|down-regulation of alpha-(1,3)-fucosyltransferase activity|negative regulation of alpha-1,3-fucosyltransferase activity|inhibition of alpha(1,3)-fucosyltransferase activity|down-regulation of alpha-1,3-fucosyltransferase activity|inhibition of alpha-(1,3)-fucosyltransferase activity|inhibition of alpha-1,3-fucosyltransferase activity|down-regulation of alpha-(1->3)-fucosyltransferase activity Any process that stops, prevents or reduces the frequency, rate or extent of alpha-(1->3)-fucosyltransferase activity. GO:1905621 positive regulation of alpha-(1->3)-fucosyltransferase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905621 up regulation of alpha-(1->3)-fucosyltransferase activity|positive regulation of alpha(1,3)-fucosyltransferase activity|up regulation of alpha(1,3)-fucosyltransferase activity|up regulation of alpha-(1,3)-fucosyltransferase activity|up regulation of alpha-1,3-fucosyltransferase activity|positive regulation of alpha-(1,3)-fucosyltransferase activity|activation of alpha-(1,3)-fucosyltransferase activity|activation of alpha-1,3-fucosyltransferase activity|positive regulation of alpha-1,3-fucosyltransferase activity|upregulation of alpha-(1->3)-fucosyltransferase activity|upregulation of alpha(1,3)-fucosyltransferase activity|up-regulation of alpha-(1,3)-fucosyltransferase activity|up-regulation of alpha-(1->3)-fucosyltransferase activity|up-regulation of alpha-1,3-fucosyltransferase activity|activation of alpha-(1->3)-fucosyltransferase activity|up-regulation of alpha(1,3)-fucosyltransferase activity|activation of alpha(1,3)-fucosyltransferase activity|upregulation of alpha-(1,3)-fucosyltransferase activity|upregulation of alpha-1,3-fucosyltransferase activity Any process that activates or increases the frequency, rate or extent of alpha-(1->3)-fucosyltransferase activity. GO:2000680 obsolete regulation of rubidium ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000680 regulation of rubidium cation transport|regulation of Rb+ transport OBSOLETE. Any process that modulates the frequency, rate or extent of rubidium ion transport. GO:2000681 obsolete negative regulation of rubidium ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000681 negative regulation of rubidium cation transport|negative regulation of Rb+ transport OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of rubidium ion transport. GO:1905622 negative regulation of leaf development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905622 down-regulation of leaf development|downregulation of leaf development|down regulation of leaf development|inhibition of leaf development Any process that stops, prevents or reduces the frequency, rate or extent of leaf development. GO:1905623 positive regulation of leaf development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905623 up-regulation of leaf development|activation of leaf development|up regulation of leaf development|upregulation of leaf development Any process that activates or increases the frequency, rate or extent of leaf development. GO:2000682 obsolete positive regulation of rubidium ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000682 positive regulation of rubidium cation transport|positive regulation of Rb+ transport OBSOLETE. Any process that activates or increases the frequency, rate or extent of rubidium ion transport. GO:1905624 regulation of L-methionine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905624 Any process that modulates the frequency, rate or extent of L-methionine import across plasma membrane. GO:2000683 regulation of cellular response to X-ray biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000683 regulation of cellular response to X-ray radiation stimulus Any process that modulates the frequency, rate or extent of cellular response to X-ray. GO:1905625 negative regulation of L-methionine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905625 Any process that stops, prevents or reduces the frequency, rate or extent of L-methionine import across plasma membrane. GO:2000684 negative regulation of cellular response to X-ray biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000684 negative regulation of cellular response to X-ray radiation stimulus Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to X-ray. GO:2000685 positive regulation of cellular response to X-ray biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000685 positive regulation of cellular response to X-ray radiation stimulus Any process that activates or increases the frequency, rate or extent of cellular response to X-ray. GO:1905626 positive regulation of L-methionine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905626 Any process that activates or increases the frequency, rate or extent of L-methionine import across plasma membrane. GO:2000686 obsolete regulation of rubidium ion transmembrane transporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000686 regulation of rubidium cation transmembrane transporter activity|regulation of rubidium transmembrane transporter activity|regulation of Rb+ transmembrane transporter activity OBSOLETE. Any process that modulates the frequency, rate or extent of rubidium ion transmembrane transporter activity. GO:1905627 regulation of serotonin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905627 regulation of serotonin biosynthesis|regulation of serotonin anabolism|regulation of serotonin synthesis|regulation of serotonin formation Any process that modulates the frequency, rate or extent of serotonin biosynthetic process. CHEBI:111763 N-demethylindolmycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_111763 GO:1905628 negative regulation of serotonin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905628 negative regulation of serotonin biosynthesis|down-regulation of serotonin biosynthetic process|down-regulation of serotonin biosynthesis|negative regulation of serotonin synthesis|down-regulation of serotonin synthesis|negative regulation of serotonin formation|down-regulation of serotonin formation|inhibition of serotonin anabolism|downregulation of serotonin biosynthetic process|downregulation of serotonin biosynthesis|inhibition of serotonin synthesis|inhibition of serotonin formation|down regulation of serotonin biosynthetic process|down regulation of serotonin biosynthesis|inhibition of serotonin biosynthetic process|inhibition of serotonin biosynthesis|down regulation of serotonin anabolism|down regulation of serotonin synthesis|downregulation of serotonin anabolism|down regulation of serotonin formation|downregulation of serotonin synthesis|downregulation of serotonin formation|negative regulation of serotonin anabolism|down-regulation of serotonin anabolism Any process that stops, prevents or reduces the frequency, rate or extent of serotonin biosynthetic process. GO:0002409 Langerhans cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002409 The movement of a Langerhans cell in response to an external stimulus. CHEBI:16399 N(3)-oxalyl-L-2,3-diaminopropionic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16399 GO:1905629 positive regulation of serotonin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905629 positive regulation of serotonin synthesis|up regulation of serotonin formation|activation of serotonin formation|positive regulation of serotonin formation|positive regulation of serotonin biosynthesis|up-regulation of serotonin anabolism|up regulation of serotonin biosynthetic process|up regulation of serotonin biosynthesis|up-regulation of serotonin synthesis|up-regulation of serotonin formation|upregulation of serotonin anabolism|upregulation of serotonin biosynthesis|upregulation of serotonin biosynthetic process|upregulation of serotonin synthesis|upregulation of serotonin formation|up regulation of serotonin anabolism|up-regulation of serotonin biosynthetic process|activation of serotonin anabolism|up-regulation of serotonin biosynthesis|activation of serotonin biosynthesis|activation of serotonin biosynthetic process|positive regulation of serotonin anabolism|up regulation of serotonin synthesis|activation of serotonin synthesis Any process that activates or increases the frequency, rate or extent of serotonin biosynthetic process. CHEBI:16397 formamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16397 CHEBI:90379 beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-Cer biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90379 CHEBI:16398 D-threonine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16398 GO:0051452 intracellular pH reduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051452 cellular acidification|cell pH reduction|intracellular acidification|reduction of cellular pH|reduction of pH in cell Any process that reduces the internal pH of a cell, measured by the concentration of the hydrogen ion. GO:0002405 antigen sampling by dendritic cells in mucosal-associated lymphoid tissue biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002405 antigen sampling by dendritic cells in MALT The process of antigen sampling carried out by dendritic cells in the mucosal-associated lymphoid tissue. CHEBI:16395 N-acetoxy-1,1'-biphenyl-4-amine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16395 GO:0051453 regulation of intracellular pH biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051453 regulation of cell pH|cellular pH regulation|cell pH regulation|pH regulation in cell Any process that modulates the internal pH of a cell, measured by the concentration of the hydrogen ion. GO:0002406 antigen sampling by M cells in mucosal-associated lymphoid tissue biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002406 antigen sampling by M cells in MALT The process of antigen samples carried out by M cells in the mucosal-associated lymphoid tissue. GO:0051450 myoblast proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051450 The multiplication or reproduction of myoblasts, resulting in the expansion of a myoblast cell population. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. GO:0002407 dendritic cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002407 The movement of a dendritic cell in response to an external stimulus. CHEBI:16393 sphingosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16393 CHEBI:16394 N-methylanthranilic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16394 GO:0002408 myeloid dendritic cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002408 The movement of a myeloid dendritic cell in response to an external stimulus. CHEBI:90376 beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90376 GO:0051451 myoblast migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051451 The orderly movement of a myoblast from one site to another, often during the development of a multicellular organism. A myoblast is a cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. GO:0002412 antigen transcytosis by M cells in mucosal-associated lymphoid tissue biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002412 antigen transport by M cells in MALT|antigen transport by M cells in mucosal-associated lymphoid tissue|antigen transcytosis by M cells in MALT The process of antigen transcytosis carried out by M cells in the mucosal-associated lymphoid tissue (MALT). Transcytosis is the process of the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. M cells are specialized epithelia cells with a microfold structure that are adept at moving antigens from the gut lumen to antigen presenting cells in the MALT. GO:0051467 detection of steroid hormone stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051467 The series of events by which a steroid hormone stimulus is received by a cell and converted into a molecular signal. CHEBI:16392 D-xylono-1,4-lactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16392 GO:0002413 tolerance induction to tumor cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002413 A process of tolerance induction which leads to immunological tolerance of a tumor. GO:0051468 detection of glucocorticoid hormone stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051468 The series of events by which a glucocorticoid hormone stimulus is received by a cell and converted into a molecular signal. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects. GO:0051465 negative regulation of corticotropin-releasing hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051465 inhibition of corticotropin-releasing hormone secretion|negative regulation of CRH secretion|negative regulation of CRF secretion|down regulation of corticotropin-releasing hormone secretion|downregulation of corticotropin-releasing hormone secretion|negative regulation of corticotropin-releasing factor secretion|down-regulation of corticotropin-releasing hormone secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of corticotropin-releasing hormone from a cell. GO:0002414 immunoglobulin transcytosis in epithelial cells biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002414 The process of transporting immunoglobulin, via transcytosis, from one side of an epithelial cell to the other. CHEBI:90360 beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_90360 CHEBI:16390 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16390 GO:0051466 positive regulation of corticotropin-releasing hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051466 up-regulation of corticotropin-releasing hormone secretion|positive regulation of CRH secretion|positive regulation of CRF secretion|upregulation of corticotropin-releasing hormone secretion|up regulation of corticotropin-releasing hormone secretion|activation of corticotropin-releasing hormone secretion|stimulation of corticotropin-releasing hormone secretion|positive regulation of corticotropin-releasing factor secretion Any process that activates or increases the frequency, rate or extent of the regulated release of corticotropin-releasing hormone from a cell. GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002415 antibody transcytosis mediated by pIgR|immunoglobulin transcytosis mediated by pIgR The process of transporting polymeric IgA and polymeric IgM immunoglobulin, via transcytosis mediated by the polymeric immunoglobulin receptor (pIgR), from the basolateral surface to apical surface of an epithelial cell. At the apical surface the immunoglobulin binding portion of the pIgRis cleaved and remains bound to the transported immunoglobulin as secretory component (SC). The same process is used for the transport and excretion of IgA immune complexes to the luminal surface of the mucosa. CHEBI:90361 alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer(d18:1/18:0) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90361 GO:0002410 plasmacytoid dendritic cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002410 The movement of a plasmacytoid dendritic cell in response to an external stimulus. GO:0051469 vesicle fusion with vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051469 heterotypic vacuole fusion (non-autophagic)|heterotypic vacuole fusion, non-autophagic The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the vacuole. GO:0002411 T cell tolerance induction to tumor cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002411 A process of tolerance induction dependent on T cells which leads to immunological tolerance of a tumor. GO:2000698 positive regulation of epithelial cell differentiation involved in kidney development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000698 Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation involved in kidney development. GO:2000699 fibroblast growth factor receptor signaling pathway involved in ureteric bud formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000699 FGF receptor signalling pathway of ureteric bud formation|FGFR signaling pathway of ureteric bud formation|fibroblast growth factor receptor signalling pathway of ureteric bud formation|fibroblast growth factor receptor signaling pathway of ureteric bud formation|FGF receptor signaling pathway of ureteric bud formation The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to the formation of the ureteric bud from the Wolffian duct. GO:1905640 response to acetaldehyde biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905640 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetaldehyde stimulus. GO:1905641 cellular response to acetaldehyde biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905641 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetaldehyde stimulus. GO:1905631 cellular response to glyceraldehyde biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905631 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glyceraldehyde stimulus. GO:2000690 regulation of cardiac muscle cell myoblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000690 regulation of cardiac myoblast differentiation|regulation of myocardial precursor cell differentiation Any process that modulates the frequency, rate or extent of cardiac muscle cell myoblast differentiation. GO:2000691 negative regulation of cardiac muscle cell myoblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000691 negative regulation of myocardial precursor cell differentiation|negative regulation of cardiac myoblast differentiation Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell myoblast differentiation. GO:1905632 protein localization to euchromatin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905632 protein localization in euchromatin|protein localisation in euchromatin|protein localisation to euchromatin A process in which a protein is transported to, or maintained in, a location within an euchromatin. GO:1905633 establishment of protein localization to euchromatin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905633 establishment of protein localization in euchromatin|establishment of protein localisation in euchromatin|establishment of protein localisation to euchromatin The directed movement of a protein to a specific location in an euchromatin. GO:2000692 negative regulation of seed maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000692 Any process that stops, prevents or reduces the frequency, rate or extent of seed maturation. GO:2000693 positive regulation of seed maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000693 Any process that activates or increases the frequency, rate or extent of seed maturation. GO:1905634 regulation of protein localization to chromatin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905634 regulation of protein localisation to chromatin Any process that modulates the frequency, rate or extent of protein localization to chromatin. GO:1905635 FACT complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905635 FACT complex formation|Facilitates chromatin transcription complex formation|Facilitates chromatin transcription complex assembly The aggregation, arrangement and bonding together of a set of components to form a FACT complex. GO:2000694 regulation of phragmoplast microtubule organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000694 regulation of phragmoplast microtubule organisation|regulation of phragmoplast microtubule cytoskeleton organization Any process that modulates the frequency, rate or extent of phragmoplast microtubule organization. GO:1905636 positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905636 upregulation of RNA polymerase II regulatory region sequence-specific DNA binding|up regulation of RNA polymerase II regulatory region sequence-specific DNA binding|activation of RNA polymerase II regulatory region sequence-specific DNA binding|up-regulation of RNA polymerase II regulatory region sequence-specific DNA binding Any process that activates or increases the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding. GO:2000695 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2000695 GO:2000696 regulation of epithelial cell differentiation involved in kidney development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000696 Any process that modulates the frequency, rate or extent of epithelial cell differentiation involved in kidney development. GO:1905637 regulation of mitochondrial mRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905637 Any process that modulates the frequency, rate or extent of mitochondrial mRNA catabolic process. GO:1905638 negative regulation of mitochondrial mRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905638 down-regulation of mitochondrial mRNA catabolic process|downregulation of mitochondrial mRNA catabolic process|down regulation of mitochondrial mRNA catabolic process|inhibition of mitochondrial mRNA catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial mRNA catabolic process. GO:2000697 negative regulation of epithelial cell differentiation involved in kidney development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2000697 Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell differentiation involved in kidney development. GO:1905639 positive regulation of mitochondrial mRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1905639 activation of mitochondrial mRNA catabolic process|up-regulation of mitochondrial mRNA catabolic process|up regulation of mitochondrial mRNA catabolic process|upregulation of mitochondrial mRNA catabolic process Any process that activates or increases the frequency, rate or extent of mitochondrial mRNA catabolic process. CHEBI:16388 4-hydroxymandelic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16388 GO:0051460 negative regulation of corticotropin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051460 downregulation of adrenocorticotropin secretion|negative regulation of adrenotropin secretion|negative regulation of adrenocorticotropin secretion|down-regulation of adrenocorticotropin secretion|negative regulation of ACTH secretion|negative regulation of adrenotropic hormone secretion|inhibition of adrenocorticotropin secretion|negative regulation of adrenocorticotropic hormone secretion|negative regulation of corticotropic hormone secretion|down regulation of adrenocorticotropin secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of corticotropic hormone from a cell. CHEBI:16389 ubiquinones biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16389 CHEBI:16387 (R)-N-methylcoclaurine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16387 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by neonatal immunoglobulin receptor|IgG antibody transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor The process of transporting IgG immunoglobulin, via transcytosis using the FcRn (also known as the neonatal Fc receptor; gene name FCGRT), from apical surface of an epithelial cell to the basolateral surface or vice versa depending on the location. This process is used for uptake of IgG from the milk in the gut in rodents, for transplacental transport of IgG from mother to embryo in humans, and for maintenance of a steady-state distribution of IgG across epithelial boundaries in general in adult mammals. GO:0051463 negative regulation of cortisol secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051463 down-regulation of cortisol secretion|downregulation of cortisol secretion|down regulation of cortisol secretion|inhibition of cortisol secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of cortisol from a cell. CHEBI:16384 trans-5-O-caffeoyl-D-quinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16384 CHEBI:90362 2-methylhexenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_90362 GO:0051464 positive regulation of cortisol secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051464 upregulation of cortisol secretion|stimulation of cortisol secretion|activation of cortisol secretion|up-regulation of cortisol secretion|up regulation of cortisol secretion Any process that activates or increases the frequency, rate or extent of the regulated release of cortisol from a cell. GO:0002417 B cell antigen processing and presentation mediated by B cell receptor uptake of antigen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002417 B-cell antigen processing and presentation mediated by B cell receptor uptake of antigen|B-lymphocyte antigen processing and presentation mediated by B cell receptor uptake of antigen|B lymphocyte antigen processing and presentation mediated by B cell receptor uptake of antigen B cell antigen processing and presentation which is initiated by uptake of antigen bound to the B cell receptor. CHEBI:16385 organic sulfide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_16385 GO:0002418 immune response to tumor cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002418 An immune system process that functions in the response of an organism to a tumor cell. CHEBI:16382 iodide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16382 GO:0051461 positive regulation of corticotropin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051461 up regulation of adrenocorticotropin secretion|activation of adrenocorticotropin secretion|stimulation of adrenocorticotropin secretion|positive regulation of adrenotropin secretion|positive regulation of adrenocorticotropic hormone secretion|positive regulation of ACTH secretion|up-regulation of adrenocorticotropin secretion|positive regulation of adrenotropic hormone secretion|positive regulation of corticotropic hormone secretion|upregulation of adrenocorticotropin secretion|positive regulation of adrenocorticotropin secretion Any process that activates or increases the frequency, rate or extent of the regulated release of corticotropin hormone from a cell. GO:0002419 T cell mediated cytotoxicity directed against tumor cell target biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002419 T-lymphocyte mediated cytotoxicity directed against tumor cell target|T-cell mediated cytotoxicity directed against tumor cell target|T lymphocyte mediated cytotoxicity directed against tumor cell target The directed killing of a tumor cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors. CHEBI:16383 cis-aconitate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_16383 GO:0051462 regulation of cortisol secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0051462 Any process that modulates the frequency, rate or extent of the regulated release of cortisol from a cell. CHEBI:507499 tricetin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_507499 CHEBI:65303 phosphatidylcholine 30:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65303 CHEBI:65309 N(omega)-methyl-L-arginine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65309 CHEBI:65305 purine deoxyribonucleotide residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65305 CHEBI:65306 pyrimidine deoxyribonucleotide residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65306 CHEBI:80946 3-octanone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_80946 CHEBI:65311 corticotropin-releasing hormone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65311 CHEBI:65314 pseudouridine 5'-phosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65314 PR:000003761 pituitary adenylate cyclase-activating polypeptide biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000003761 PACAP|ADCYAP1 A protein that is a translation product of the human ADCYAP1 gene or a 1:1 ortholog thereof. CHEBI:65315 uridine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65315 CHEBI:65316 L-tyrosine-O-sulfate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65316 CHEBI:65317 2'-deoxynucleoside 5'-monophosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65317 CHEBI:65318 cyanophycin macromolecule biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65318 CHEBI:65322 hemiterpenoid indole alkaloid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65322 CHEBI:65323 monoterpenoid indole alkaloid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65323 CHEBI:65320 pseudouridine 5'-phosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65320 CHEBI:65321 terpenoid indole alkaloid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65321 CHEBI:65327 D-xylose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65327 PR:000003777 adiponectin biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000003777 adipocyte complement-related 30 kDa protein|APM1|ADIPOQ|adipose most abundant gene transcript 1 protein|apM-1|gelatin-binding protein|ACRP30|ACDC|adipocyte, C1q and collagen domain-containing protein|adipocyte-specific protein AdipoQ|GBP28|30 kDa adipocyte complement-related protein A protein that is a translation product of the human ADIPOQ gene or a 1:1 ortholog thereof. CHEBI:65328 L-xylose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65328 GO:0002489 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002489 TAP-dependent antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway|TAP-dependent endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway|endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway, TAP-dependent The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class Ib molecule. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family. GO:0002485 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002485 endogenous peptide antigen processing and presentation via MHC class I via ER pathway, TAP-dependent|TAP-dependent endogenous peptide antigen processing and presentation via MHC class I via ER pathway|TAP-dependent antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-dependent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following TAP-dependent transport from the cytosol. Class I here refers to classical class I molecules. GO:0002486 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002486 TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway|endogenous peptide antigen processing and presentation via MHC class I via ER pathway, TAP-independent|TAP-independent endogenous peptide antigen processing and presentation via MHC class I via ER pathway The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-independent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following transport from the cytosol via a TAP-independent pathway. Class I here refers to classical class I molecules. GO:0002487 antigen processing and presentation of endogenous peptide antigen via MHC class I via endolysosomal pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002487 endogenous peptide antigen processing and presentation via MHC class I via endolysosomal pathway The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in an endolysosome. Class I here refers to classical class I molecules. GO:0002488 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002488 endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class Ib molecule in the ER. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family. GO:0002481 antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002481 TAP-dependent antigen processing and presentation of exogenous peptide antigen via MHC class Ib|TAP-dependent exogenous peptide antigen processing and presentation via MHC class Ib|exogenous peptide antigen processing and presentation via MHC class Ib, TAP-dependent The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class Ib molecule. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family. CHEBI:80963 3-(2'-Methylthio)ethylmalic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_80963 GO:0002482 antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-independent biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002482 TAP-independent exogenous peptide antigen processing and presentation via MHC class Ib|TAP-independent antigen processing and presentation of exogenous peptide antigen via MHC class Ib|exogenous peptide antigen processing and presentation via MHC class Ib, TAP-independent The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family. CHEBI:80964 3-(3'-Methylthio)propylmalic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_80964 CHEBI:65335 3-deoxy-D-manno-octulosonate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_65335 GO:0002483 antigen processing and presentation of endogenous peptide antigen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002483 endogenous peptide antigen processing and presentation The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002484 endogenous peptide antigen processing and presentation via MHC class I via ER pathway The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER. Class I here refers to classical class I molecules. CHEBI:65331 alkyl caffeate ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65331 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002480 TAP-independent exogenous peptide antigen processing and presentation via MHC class I|cross presentation|exogenous peptide antigen processing and presentation via MHC class I, TAP-independent|cross-presentation|TAP-independent antigen processing and presentation of exogenous peptide antigen via MHC class I The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class I here refers to classical class I molecules. GO:0002496 proteolysis associated with antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002496 The hydrolysis of a peptide bond or bonds within a protein contributing to antigen processing and presentation. GO:0002497 proteasomal proteolysis associated with antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002497 The hydrolysis of a peptide bond or bonds within a protein by the proteasome complex contributing to antigen processing and presentation. GO:0002498 proteolysis within endoplasmic reticulum associated with antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002498 proteolysis within ER associated with antigen processing and presentation|endoplasmic reticulum proteolysis associated with antigen processing and presentation|ER proteolysis associated with antigen processing and presentation The hydrolysis of a peptide bond or bonds within a protein by ER resident proteases contributing to antigen processing and presentation. GO:0002499 proteolysis within endosome associated with antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002499 endosomal proteolysis associated with antigen processing and presentation The hydrolysis of a peptide bond or bonds within a protein by endosomal resident proteases contributing to antigen processing and presentation. GO:0002492 peptide antigen assembly with MHC class Ib protein complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002492 The binding of a peptide antigen to the antigen binding groove of an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family. GO:0002493 lipid antigen assembly with MHC class Ib protein complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002493 The binding of a lipid antigen to the antigen binding groove of an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the CD1 gene family. GO:0002494 lipid antigen transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002494 The directed movement of a lipid antigen into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0002495 antigen processing and presentation of peptide antigen via MHC class II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002495 peptide antigen processing and presentation via MHC class II The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein. CHEBI:65340 5-formyltetrahydrofolate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65340 CHEBI:65341 5-HETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65341 GO:0002490 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-independent biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002490 endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway, TAP-independent|TAP-independent endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway|TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family. CHEBI:65342 5-oxo-ETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_65342 GO:0002491 antigen processing and presentation of endogenous peptide antigen via MHC class II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0002491 endogenous peptide antigen processing and presentation via MHC class II The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein. CHEBI:79985 flavanone 7-O-[alpha-L-rhamnosyl-(1->2)-beta-D-glucoside] biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79985 GO:0021780 glial cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021780 The process in which a cell becomes capable of differentiating autonomously into a glial cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. GO:0031108 holo-[acyl-carrier-protein] biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031108 holo-[acyl-carrier-protein] anabolism|holo-[acyl-carrier-protein] synthesis|holo-[acyl-carrier-protein] formation|holo-[acyl-carrier-protein] biosynthesis|holo-[acyl-carrier protein] biosynthesis The chemical reactions and pathways resulting in the formation of holo-[acyl-carrier protein]. GO:0021781 glial cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021781 The process in which the developmental fate of a cell becomes restricted such that it will develop into a glial cell. GO:0021782 glial cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021782 The process aimed at the progression of a glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. GO:0031109 microtubule polymerization or depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031109 Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule. GO:0031106 septin ring organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031106 septin ring organisation Control of the formation, spatial distribution, and breakdown of the septin ring. GO:0021783 preganglionic parasympathetic fiber development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021783 The process whose specific outcome is the progression of a preganglionic parasympathetic fiber over time, from its formation to the mature structure. A preganglionic parasympathetic fiber is a cholinergic axonal fiber projecting from the CNS to a parasympathetic ganglion. GO:0031107 septin ring disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031107 The controlled breakdown of a septin ring. GO:0021784 postganglionic parasympathetic fiber development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021784 The process whose specific outcome is the progression of the postganglionic portion of the parasympathetic fiber over time, from its formation to the mature structure. The parasympathetic fiber is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia. GO:0006148 inosine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006148 inosine breakdown|inosine catabolism|inosine degradation The chemical reactions and pathways resulting in the breakdown of inosine, hypoxanthine riboside, a nucleoside found free but not in combination in nucleic acids except in the anticodons of some tRNAs. GO:0021785 branchiomotor neuron axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021785 special visceral motor neuron axon guidance|branchial motor axon guidance|BMN axon guidance The process in which a branchiomotor neuron growth cone is directed to a specific target site. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx. GO:0031104 dendrite regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031104 The regrowth of dendrites in response to their loss or damage. GO:0031105 septin complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0031105 A protein complex containing septins. Typically, these complexes contain multiple septins and are oligomeric. GO:0021786 branchiomotor neuron axon guidance in neural tube biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021786 The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx. GO:0006149 deoxyinosine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006149 deoxyinosine degradation|deoxyinosine breakdown|deoxyinosine catabolism The chemical reactions and pathways resulting in the breakdown of deoxyinosine, hypoxanthine deoxyriboside. GO:0006146 adenine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006146 adenine catabolism|adenine degradation|adenine breakdown The chemical reactions and pathways resulting in the breakdown of adenine, 6-aminopurine, one of the 5 main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine. GO:0045754 positive regulation of acetate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045754 stimulation of acetate catabolic process|up-regulation of acetate catabolic process|upregulation of acetate catabolic process|positive regulation of acetate degradation|positive regulation of acetate breakdown|positive regulation of acetate catabolism|up regulation of acetate catabolic process|activation of acetate catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate. PR:000007495 fibroblast growth factor 4 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000007495 heparin secretory-transforming protein 1|K-fibroblast growth factor|KS3|transforming protein KS3|HSTF-1|HBGF-4|HST|heparin-binding growth factor 4|Kfgf|FGF4|HSTF1|HST-1|FGF-4 A protein that is a translation product of the human FGF4 gene or a 1:1 ortholog thereof. PR:000007496 fibroblast growth factor 5 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000007496 Smag-82|HBGF-5|heparin-binding growth factor 5|FGF5|FGF-5 A protein that is a translation product of the human FGF5 gene or a 1:1 ortholog thereof. GO:0045755 negative regulation of initiation of acetate catabolic process by acetate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045755 down-regulation of initiation of acetate catabolic process by acetate|negative regulation of initiation of acetate breakdown by acetate|negative regulation of initiation of acetate degradation by acetate|downregulation of initiation of acetate catabolic process by acetate|down regulation of initiation of acetate catabolic process by acetate|inhibition of initiation of acetate catabolic process by acetate Any process that stops or prevents the activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate. GO:0006147 guanine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006147 guanine degradation|guanine catabolism|guanine breakdown The chemical reactions and pathways resulting in the breakdown of guanine, 2-amino-6-hydroxypurine, a purine that is one of the five main bases found in nucleic acids and a component of a number of phosphorylated guanosine derivatives whose metabolic or regulatory functions are important. PR:000007497 fibroblast growth factor 6 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000007497 heparin secretory-transforming protein 2|HST2|HBGF-6|HSTF-2|heparin-binding growth factor 6|FGF6|HSTF2|FGF-6|HST-2 A protein that is a translation product of the human FGF6 gene or a 1:1 ortholog thereof. GO:0006144 purine nucleobase metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006144 purine base metabolism|purine base metabolic process|purine metabolic process|purine metabolism The chemical reactions and pathways involving purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine. GO:0045752 positive regulation of Toll signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045752 up regulation of Toll signaling pathway|positive regulation of Tl signalling pathway|positive regulation of Tl signaling pathway|upregulation of Toll signaling pathway|stimulation of Toll signaling pathway|up-regulation of Toll signaling pathway|activation of Toll signaling pathway Any process that activates or increases the frequency, rate or extent of the Tl signaling pathway. GO:0006145 purine nucleobase catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006145 purine base catabolic process|purine base catabolism|purine base degradation|purine base breakdown The chemical reactions and pathways resulting in the breakdown of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine. GO:0045753 negative regulation of acetate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045753 down-regulation of acetate catabolic process|inhibition of acetate catabolic process|down regulation of acetate catabolic process|negative regulation of acetate catabolism|negative regulation of acetate degradation|downregulation of acetate catabolic process|negative regulation of acetate breakdown Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate. GO:0045750 obsolete positive regulation of S phase of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045750 positive regulation of S-phase of mitotic cell cycle|upregulation of S phase of mitotic cell cycle|up regulation of S phase of mitotic cell cycle|positive regulation of S phase of mitotic cell cycle|activation of S phase of mitotic cell cycle|stimulation of S phase of mitotic cell cycle|up-regulation of S phase of mitotic cell cycle OBSOLETE. Any process that activates or increases the frequency, rate or extent of S phase of mitotic cell cycle activity. GO:0006142 regulation of pyrimidine nucleobase metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006142 regulation of pyrimidine base metabolic process|regulation of pyrimidine base metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine nucleobases. GO:0006143 obsolete purine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006143 purine metabolic process OBSOLETE. (Was not defined before being made obsolete). GO:0045751 negative regulation of Toll signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045751 down-regulation of Toll signaling pathway|negative regulation of Tl signaling pathway|downregulation of Toll signaling pathway|negative regulation of Tl signalling pathway|down regulation of Toll signaling pathway|inhibition of Toll signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the Tl signaling pathway. GO:0070709 RNA guanosine insertion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070709 RNA G insertion The modification of an RNA molecule by insertion of a guanosine nucleotide. GO:0006140 regulation of nucleotide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006140 regulation of nucleotide metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleotides. PR:000007494 fibroblast growth factor 3 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000007494 HBGF-3|INT2|heparin-binding growth factor 3|proto-oncogene Int-2|INT-2 proto-oncogene protein|Int-2|FGF3|FGF-3 A protein that is a translation product of the human FGF3 gene or a 1:1 ortholog thereof. GO:0006141 regulation of purine nucleobase metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006141 regulation of purine base metabolic process|regulation of purine base metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving purines. GO:0070718 alphaPDGFR-SHP-2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070718 PDGFRA-SHP-2 complex, PDGF stimulated A protein complex that contains the platelet-derived growth factor alpha receptor (alphaPDGFR; PDGFRA) and the adaptor protein SHP-2, and is involved signaling via the PDGFR signaling pathway. GO:0006150 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006150 GO:0070719 alphaPDGFR-PLC-gamma-1-PI3K-SHP-2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070719 PDGFRA-PLC-gamma-1-PI3K-SHP-2 complex, PDGF stimulated A protein complex that contains the platelet-derived growth factor alpha receptor (alphaPDGFR; PDGFRA), phospholipase C-gamma-1 (PLC-gamma-1), phosphatidylinositol 3-kinase (PI3K) and the adaptor protein SHP-2, and is involved signaling via the PDGFR signaling pathway. GO:0070716 mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070716 mismatch repair involved in maintenance of fidelity during DNA-dependent DNA replication A mismatch repair process that corrects errors introduced that ensures the accuracy of DNA replication. GO:0070717 poly-purine tract binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070717 Interacting selectively and non-covalently with any stretch of purines (adenine or guanine) in an RNA molecule. GO:0070714 RNA guanosine-uridine insertion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070714 RNA GU insertion The modification of an RNA molecule by insertion of an guanosine-uridine insertion dinucleotide. GO:0045758 obsolete positive regulation of actin polymerization and/or depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045758 positive regulation of actin polymerization and/or depolymerization OBSOLETE. Any process that activates or increases the frequency, rate or extent of actin polymerization and/or depolymerization. GO:0045759 negative regulation of action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045759 down regulation of action potential|inhibition of action potential|down-regulation of action potential|downregulation of action potential Any process that stops, prevents, or reduces the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. GO:0070715 sodium-dependent organic cation transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070715 The directed, sodium-dependent, movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0045756 positive regulation of initiation of acetate catabolic process by acetate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045756 activation of initiation of acetate catabolic process by acetate|up-regulation of initiation of acetate catabolic process by acetate|up regulation of initiation of acetate catabolic process by acetate|positive regulation of initiation of acetate breakdown by acetate|positive regulation of initiation of acetate degradation by acetate|upregulation of initiation of acetate catabolic process by acetate|stimulation of initiation of acetate catabolic process by acetate Any process that activates or increases the frequency, rate or extent of the activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate. GO:0070712 RNA cytidine-uridine insertion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070712 RNA CU insertion The modification of an RNA molecule by insertion of an cytidine-uridine dinucleotide. GO:0070713 RNA guanosine-cytidine insertion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070713 RNA GC insertion The modification of an RNA molecule by insertion of an guanosine-cytidine dinucleotide. GO:0045757 obsolete negative regulation of actin polymerization and/or depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045757 negative regulation of actin polymerization and/or depolymerization OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of actin polymerization and/or depolymerization. GO:0070710 RNA uridine deletion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070710 RNA uridine excision|RNA U deletion The modification of an RNA molecule by removal of a uridine nucleotide. GO:0021787 chemorepulsion of branchiomotor neuron axon in neural tube biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021787 negative chemotaxis of branchiomotor neuron axon in neural tube The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube in response to a repulsive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx. GO:0031102 neuron projection regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031102 neurite regeneration The regrowth of neuronal processes such as axons or dendrites in response to their loss or damage. GO:0070711 RNA adenosine-uridine insertion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070711 RNA AU insertion The modification of an RNA molecule by insertion of an adenosine-uridine dinucleotide. GO:0021788 chemoattraction of branchiomotor neuron axon in neural tube biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021788 positive chemotaxis of branchiomotor neuron axon in neural tube The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube in response to an attractive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx. GO:0031103 axon regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031103 The regrowth of axons following their loss or damage. GO:0021789 branchiomotor neuron axon guidance in branchial arch mesenchyme biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021789 The process in which a branchiomotor neuron growth cone in the branchial arch mesenchyme is directed to a specific target site in the branchial arch mesenchyme. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx. GO:0031100 animal organ regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031100 The regrowth of a lost or destroyed animal organ. GO:0031101 fin regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031101 The regrowth of fin tissue following its loss or destruction. GO:0021770 parahippocampal gyrus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021770 Wikipedia:parahippocampal_gyrus hippocampal gyrus development The progression of the parahippocampal gyrus over time from its initial formation until its mature state. The parahippocampal gyrus is a ridge in the cerebral cortex. GO:0021771 lateral geniculate nucleus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021771 LGN development The progression of the lateral geniculate nucleus over time from its initial formation until its mature state. The lateral geniculate nucleus is the primary processor of visual information received from the retina. GO:0021772 olfactory bulb development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021772 The progression of the olfactory bulb over time from its initial formation until its mature state. The olfactory bulb coordinates neuronal signaling involved in the perception of smell. It receives input from the sensory neurons and outputs to the olfactory cortex. GO:0021773 striatal medium spiny neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021773 striatal MSN differentiation|medium-sized spiny neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a medium spiny neuron residing in the striatum. GO:0021774 retinoic acid receptor signaling pathway involved in ventral spinal cord interneuron specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021774 retinoic acid receptor signalling pathway involved in ventral spinal cord interneuron specification The series of molecular signals initiated by binding of a ligand to a retinoic acid receptor in a precursor cell in the ventral spinal cord that contributes to the commitment of the precursor cell to an interneuron fate. GO:0006159 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006159 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021775 hh signaling pathway involved in ventral spinal cord interneuron specification|hedgehog signaling pathway involved in ventral spinal cord interneuron specification|smoothened signalling pathway involved in ventral spinal cord interneuron specification The series of molecular signals initiated by binding of a ligand to the transmembrane receptor smoothened in a precursor cell in the ventral spinal cord that contributes to the commitment of the precursor cell to an interneuron fate. GO:0045765 regulation of angiogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045765 Any process that modulates the frequency, rate or extent of angiogenesis. GO:0006157 deoxyadenosine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006157 deoxyadenosine degradation|deoxyadenosine breakdown|deoxyadenosine phosphorolysis|deoxyadenosine catabolism The chemical reactions and pathways resulting in the breakdown of deoxyadenosine, 2-deoxyribosyladenine, one of the four major nucleosides of DNA. GO:0045766 positive regulation of angiogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045766 stimulation of angiogenesis|activation of angiogenesis|up-regulation of angiogenesis|up regulation of angiogenesis|upregulation of angiogenesis Any process that activates or increases angiogenesis. GO:0006158 obsolete deoxyadenosine deaminase reaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006158 deoxyadenosine deaminase reaction OBSOLETE. (Was not defined before being made obsolete). GO:0045763 negative regulation of cellular amino acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045763 inhibition of amino acid metabolic process|negative regulation of amino acid metabolism|down-regulation of amino acid metabolic process|downregulation of amino acid metabolic process|down regulation of amino acid metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amino acid. GO:0006155 obsolete adenosine deaminase reaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006155 adenosine deaminase reaction OBSOLETE. (Was not defined before being made obsolete). GO:0045764 positive regulation of cellular amino acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045764 upregulation of amino acid metabolic process|positive regulation of amino acid metabolism|stimulation of amino acid metabolic process|activation of amino acid metabolic process|up-regulation of amino acid metabolic process|up regulation of amino acid metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amino acid. GO:0006156 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006156 GO:0045761 regulation of adenylate cyclase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045761 adenylate cyclase regulator|regulation of adenylyl cyclase activity Any process that modulates the frequency, rate or extent of adenylate cyclase activity. GO:0006153 obsolete purine nucleosidase reaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006153 purine nucleosidase reaction OBSOLETE. (Was not defined before being made obsolete). GO:0045762 positive regulation of adenylate cyclase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045762 stimulation of adenylate cyclase activity|positive regulation of adenylyl cyclase activity|up-regulation of adenylate cyclase activity|up regulation of adenylate cyclase activity|adenylate cyclase activator|upregulation of adenylate cyclase activity Any process that activates or increases the frequency, rate or extent of adenylate cyclase activity. GO:0006154 adenosine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006154 adenosine phosphorolysis|adenosine catabolism|adenosine degradation|adenosine breakdown The chemical reactions and pathways resulting in the breakdown of adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes. GO:0006151 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006151 GO:0045760 positive regulation of action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045760 up regulation of action potential|upregulation of action potential|stimulation of action potential|up-regulation of action potential|activation of action potential Any process that activates or increases the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. GO:0006152 purine nucleoside catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006152 purine nucleoside degradation|purine nucleoside breakdown|purine nucleoside catabolism The chemical reactions and pathways resulting in the breakdown of purine nucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside). GO:0070707 RNA dinucleotide insertion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070707 The modification of an RNA molecule by insertion of a dinucleotide. GO:0006160 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006160 GO:0070708 RNA cytidine insertion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070708 RNA C insertion The modification of an RNA molecule by insertion of a cytidine nucleotide. GO:0006161 deoxyguanosine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006161 deoxyguanosine breakdown|deoxyguanosine catabolism|deoxyguanosine degradation The chemical reactions and pathways resulting in the breakdown of deoxyguanosine, a nucleoside consisting of the base guanine and the sugar deoxyribose. GO:0070705 RNA nucleotide insertion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070705 The modification of an RNA molecule by insertion of one or more nucleotides. GO:0070706 RNA nucleotide deletion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070706 RNA nucleotide excision The modification of an RNA molecule by removal of a single nucleotide. GO:0045769 negative regulation of asymmetric cell division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045769 down regulation of asymmetric cell division|inhibition of asymmetric cell division|down-regulation of asymmetric cell division|downregulation of asymmetric cell division Any process that stops, prevents, or reduces the frequency, rate or extent of asymmetric cell division. GO:0070703 outer mucus layer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070703 The outer of two mucus layers secreted by epithelial cells in the colon; the outer mucus layer is loosely packed and can be colonized by bacteria. GO:0070704 sterol desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070704 Catalysis of the introduction of a double bond into a sterol molecule. GO:0045767 obsolete regulation of anti-apoptosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045767 regulation of anti-apoptosis OBSOLETE. Any process that modulates the frequency, rate or extent of anti-apoptosis. GO:0070701 mucus layer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070701 mucus|mucous|extracellular proteinaceous gel|mucous layer An extracellular region part that consists of a protective layer of mucus secreted by epithelial cells lining tubular organs of the body such as the colon or secreted into fluids such as saliva. Mucus is a viscous slimy secretion consisting of mucins (i.e. highly glycosylated mucin proteins) and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes. GO:0070702 inner mucus layer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070702 The inner of two mucus layers secreted by epithelial cells in the colon; the inner mucus layer is firmly attached to the epithelium, is densely packed with a compact stratified appearance and is devoid of bacteria. GO:0045768 obsolete positive regulation of anti-apoptosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045768 stimulation of anti-apoptosis|activation of anti-apoptosis|up-regulation of anti-apoptosis|positive regulation of anti-apoptosis|up regulation of anti-apoptosis|upregulation of anti-apoptosis OBSOLETE. Any process that activates or increases the frequency, rate or extent of anti-apoptosis. GO:0021776 smoothened signaling pathway involved in spinal cord motor neuron cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021776 hedgehog signaling pathway involved in spinal cord motor neuron cell fate specification|hh signaling pathway involved in spinal cord motor neuron cell fate specification|smoothened signalling pathway involved in spinal cord motor neuron cell fate specification The series of molecular signals initiated by binding of a ligand to the transmembrane receptor smoothened in a precursor cell in the spinal cord that contributes to the process of a precursor cell becoming capable of differentiating autonomously into a motor neuron in an environment that is neutral with respect to the developmental pathway. GO:0021777 obsolete BMP signaling pathway involved in spinal cord association neuron specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021777 BMP signalling pathway involved in spinal cord association neuron specification|bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification OBSOLETE. A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to its commitment to an association neuron fate. GO:0070700 BMP receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070700 bone morphogenetic protein receptor binding Interacting selectively and non-covalently with a BMP receptor. GO:0021778 oligodendrocyte cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021778 The process in which a cell becomes capable of differentiating autonomously into an oligodendrocyte in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. GO:0021779 oligodendrocyte cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021779 The process in which the developmental fate of a cell becomes restricted such that it will develop into an oligodendrocyte. GO:0006128 obsolete oxidized glutathione reduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006128 oxidized glutathione reduction OBSOLETE. (Was not defined before being made obsolete). GO:0021761 limbic system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021761 The progression of the limbic system over time from its initial formation until its mature state. The limbic system is a collection of structures in the brain involved in emotion, motivation and emotional aspects of memory. GO:0021762 substantia nigra development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021762 The progression of the substantia nigra over time from its initial formation until its mature state. The substantia nigra is the layer of gray substance that separates the posterior parts of the cerebral peduncles (tegmentum mesencephali) from the anterior parts; it normally includes a posterior compact part with many pigmented cells (pars compacta) and an anterior reticular part whose cells contain little pigment (pars reticularis). GO:0006129 obsolete protein-disulfide reduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006129 protein-disulfide reduction|protein-disulphide reduction OBSOLETE. (Was not defined before being made obsolete). GO:0006126 obsolete other pathways of electron transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006126 other pathways of electron transport OBSOLETE. (Was not defined before being made obsolete). GO:0021763 subthalamic nucleus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021763 corpus luysi development The progression of the subthalamic nucleus over time from its initial formation until its mature state. The subthalamic nucleus is the lens-shaped nucleus located in the ventral part of the subthalamus on the inner aspect of the internal capsule that is concerned with the integration of somatic motor function. GO:0021764 amygdala development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021764 The progression of the amygdala over time from its initial formation until its mature state. The amygdala is an almond-shaped set of neurons in the medial temporal lobe of the brain that play a key role in processing emotions such as fear and pleasure. GO:0006127 glycerophosphate shuttle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006127 MetaCyc:PWY-6118 The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise glycerol 3-phosphate in the cytosol; this compound is then transported into the mitochondria where it is converted to dihydroxyacetone phosphate (DHAP) using FAD; DHAP then returns to the cytosol to complete the cycle. GO:0045776 negative regulation of blood pressure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045776 downregulation of blood pressure|down regulation of blood pressure|inhibition of blood pressure|down-regulation of blood pressure Any process in which the force of blood traveling through the circulatory system is decreased. GO:0006124 ferredoxin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006124 ferredoxin metabolism The chemical reactions and pathways involving ferredoxin, any simple, nonenzymatic iron-sulfur protein that is characterized by having equal numbers of atoms of iron and labile sulfur. Iron and sulfur atoms are present in one or two clusters of two or four atoms of each. GO:0006125 obsolete thioredoxin pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006125 MetaCyc:THIOREDOX-PWY thioredoxin reduction|thioredoxin pathway OBSOLETE. This term was not defined before being made obsolete. GO:0045777 positive regulation of blood pressure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045777 upregulation of blood pressure|stimulation of blood pressure|up-regulation of blood pressure|activation of blood pressure|up regulation of blood pressure Any process in which the force of blood traveling through the circulatory system is increased. GO:0045774 negative regulation of beta 2 integrin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045774 negative regulation of beta 2 integrin anabolism|downregulation of beta 2 integrin biosynthetic process|negative regulation of beta 2 integrin synthesis|down regulation of beta 2 integrin biosynthetic process|negative regulation of beta 2 integrin formation|inhibition of beta 2 integrin biosynthetic process|negative regulation of beta 2 integrin biosynthesis|down-regulation of beta 2 integrin biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta 2 integrins. GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006122 complex III (ubiquinone to cytochrome c) The transfer of electrons from ubiquinol to cytochrome c that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex III. GO:0045775 positive regulation of beta 2 integrin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045775 up regulation of beta 2 integrin biosynthetic process|positive regulation of beta 2 integrin synthesis|positive regulation of beta 2 integrin formation|upregulation of beta 2 integrin biosynthetic process|stimulation of beta 2 integrin biosynthetic process|up-regulation of beta 2 integrin biosynthetic process|activation of beta 2 integrin biosynthetic process|positive regulation of beta 2 integrin biosynthesis|positive regulation of beta 2 integrin anabolism Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta 2 integrins. GO:0006123 mitochondrial electron transport, cytochrome c to oxygen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006123 complex IV (reduction of O2) The transfer of electrons from cytochrome c to oxygen that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex IV. GO:0045772 positive regulation of autophagosome size biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045772 positive regulation of autophagic vacuole size|up regulation of autophagic vacuole size|activation of autophagic vacuole size|stimulation of autophagic vacuole size|up-regulation of autophagic vacuole size|upregulation of autophagic vacuole size Any process that increases autophagosome size. GO:0006120 mitochondrial electron transport, NADH to ubiquinone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006120 complex I (NADH to ubiquinone)|oxidative phosphorylation, NADH to ubiquinone The transfer of electrons from NADH to ubiquinone that occurs during oxidative phosphorylation. GO:0006121 mitochondrial electron transport, succinate to ubiquinone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006121 mitochondrial electron transport, succinate to coenzyme Q|oxidative phosphorylation, succinate to ubiquinone|complex II (succinate to ubiquinone) The transfer of electrons from succinate to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex II. GO:0045773 positive regulation of axon extension biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045773 stimulation of axon extension|up-regulation of axon extension|activation of axon extension|up regulation of axon extension|upregulation of axon extension Any process that activates or increases the frequency, rate or extent of axon extension. GO:0045770 positive regulation of asymmetric cell division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045770 up regulation of asymmetric cell division|upregulation of asymmetric cell division|stimulation of asymmetric cell division|up-regulation of asymmetric cell division|activation of asymmetric cell division Any process that activates or increases the frequency, rate or extent of asymmetric cell division. GO:0045771 negative regulation of autophagosome size biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045771 down regulation of autophagic vacuole size|downregulation of autophagic vacuole size|negative regulation of autophagic vacuole size|down-regulation of autophagic vacuole size|inhibition of autophagic vacuole size Any process that reduces autophagosome size. GO:0070738 tubulin-glycine ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070738 tubulin glycylase activity Catalysis of the posttranslational transfer of one or more glycine residues to a specific glutamate residue on a target tubulin molecule; acts on alpha or beta tubulin. GO:0070739 protein-glutamic acid ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070739 protein-glutamate ligase activity|protein glutamylase activity Catalysis of the posttranslational transfer of one or more glutamate residues to a specific residue on a target protein. GO:0070736 protein-glycine ligase activity, initiating biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070736 protein glycylase activity, initiating Catalysis of the posttranslational transfer of a glycine residue to the gamma-carboxyl group(s) of one or more specific glutamate residues on a target protein. GO:0070737 protein-glycine ligase activity, elongating biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070737 protein glycylase activity, elongating Catalysis of the posttranslational transfer of one or more glycine residues to a glycine residue covalently attached to the gamma-carboxyl group of a glutamate residue on a target protein, resulting in the elongation of a polyglycine side chain. GO:0070734 histone H3-K27 methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070734 histone H3 K27 methylation|histone H3K27me|histone lysine H3 K27 methylation The modification of histone H3 by addition of one or more methyl groups to lysine at position 27 of the histone. GO:0045778 positive regulation of ossification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045778 upregulation of ossification|stimulation of ossification|activation of ossification|up-regulation of ossification|positive regulation of bone formation|positive regulation of bone biosynthesis|up regulation of ossification Any process that activates or increases the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance. GO:0070735 protein-glycine ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070735 Reactome:R-HSA-8867370 protein glycylase activity Catalysis of the posttranslational transfer of one or more glycine residues to a specific glutamate residue on a target protein. GO:0045779 negative regulation of bone resorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045779 down-regulation of bone resorption|inhibition of bone resorption|down regulation of bone resorption|downregulation of bone resorption Any process that stops, prevents, or reduces the frequency, rate or extent of bone resorption. GO:0070732 spindle envelope biolink:CellularComponent go-plus goslim_candida http://purl.obolibrary.org/obo/GO_0070732 An organelle envelope that surrounds the chromosomes and the central part of the spindle apparatus during mitosis and meiosis; observed in many invertebrates. The spindle envelope consists of membrane layers, called parafusorial membranes, derived from endoplasmic reticulum membrane; in male meiosis it forms during prometaphase and persists until early in the ensuing interphase. GO:0021765 cingulate gyrus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021765 The progression of the cingulate gyrus over time from its initial formation until its mature state. The cingulate gyrus is a ridge in the cerebral cortex located dorsal to the corpus callosum. GO:0070733 protein adenylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070733 EC:2.7.7.n1 AMPylator|adenosine monophosphate-protein transferase activity Catalysis of the reaction: ATP + protein = diphosphate + adenylyl-protein; mediates the addition of an adenylyl (adenosine 5'-monophosphate; AMP group) to specific residues of target proteins. GO:0021766 hippocampus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021766 hippocampal formation development The progression of the hippocampus over time from its initial formation until its mature state. GO:0070730 cAMP transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070730 cyclic AMP transport The directed movement of cyclic AMP (cAMP), into, out of or within a cell. GO:0021767 mammillary body development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021767 The progression of the mammillary body over time from its initial formation until its mature state. The mammillary body is a protrusion at the posterior end of the hypothalamus that contains hypothalamic nuclei. GO:0070731 cGMP transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070731 cyclic GMP transport The directed movement of cyclic GMP (cGMP), into, out of or within a cell. GO:0021768 nucleus accumbens development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021768 ventral striatum development|accumbens nucleus development The progression of the nucleus accumbens over time from its initial formation until its mature state. The nucleus accumbens is a collection of pleomorphic cells in the caudal part of the anterior horn of the lateral ventricle, in the region of the olfactory tubercle, lying between the head of the caudate nucleus and the anterior perforated substance. It is part of the ventral striatum, a composite structure considered part of the basal ganglia. GO:0021769 orbitofrontal cortex development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021769 The progression of the orbitofrontal cortex over time from its initial formation until its mature state. The orbitofrontal cortex is a cerebral cortex region located in the frontal lobe. GO:0045780 positive regulation of bone resorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045780 up regulation of bone resorption|activation of bone resorption|stimulation of bone resorption|up-regulation of bone resorption|upregulation of bone resorption Any process that activates or increases the frequency, rate or extent of bone resorption. GO:0006139 nucleobase-containing compound metabolic process biolink:BiologicalProcess go-plus goslim_plant|goslim_pir http://purl.obolibrary.org/obo/GO_0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|nucleobase, nucleoside and nucleotide metabolic process|nucleobase, nucleoside, nucleotide and nucleic acid metabolism|cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolism|cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolic process Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids. GO:0055106 ubiquitin-protein transferase regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0055106 Modulates the activity of a ubiquitin-protein transferase, an enzyme that catalyzes the covalent attachment of ubiquitin to lysine in a substrate protein. GO:0021750 vestibular nucleus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021750 The process whose specific outcome is the progression of the vestibular nucleus over time, from its formation to the mature structure. GO:0055107 Golgi to secretory granule transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055107 The directed movement of proteins from the Golgi to a secretory granule. The secretory granule is a membrane-bounded particle, usually protein, formed in the granular endoplasmic reticulum and the Golgi complex. GO:0021751 salivary nucleus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021751 The process whose specific outcome is the progression of a salivary nucleus over time, from its formation to the mature structure. GO:0055108 Golgi to transport vesicle transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055108 The directed movement of proteins from the Golgi to a transport vesicle. Continuously secreted proteins are sorted into transport vesicles that fuse with the plasma membrane, releasing their contents by exocytosis. GO:0006137 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006137 GO:0021752 inferior salivary nucleus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021752 The process whose specific outcome is the progression of the inferior salivary nucleus over time, from its formation to the mature structure. GO:0006138 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006138 GO:0055109 invagination involved in gastrulation with mouth forming second biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055109 The infolding of the epithelial sheet into the embryo involved in deuterostomic gastrulation. GO:0021753 superior salivary nucleus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021753 The process whose specific outcome is the progression of the superior salivary nucleus over time, from its formation to the mature structure. GO:0045787 positive regulation of cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045787 stimulation of progression through cell cycle|up-regulation of progression through cell cycle|positive regulation of progression through cell cycle|activation of progression through cell cycle|up regulation of progression through cell cycle|positive regulation of cell cycle progression|upregulation of progression through cell cycle Any process that activates or increases the rate or extent of progression through the cell cycle. GO:0006135 obsolete dihydropteridine reduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006135 dihydropteridine reduction OBSOLETE. (Was not defined before being made obsolete). GO:0006136 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006136 GO:0045788 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045788 GO:0045785 positive regulation of cell adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045785 up-regulation of cell adhesion|upregulation of cell adhesion|up regulation of cell adhesion|activation of cell adhesion|stimulation of cell adhesion Any process that activates or increases the frequency, rate or extent of cell adhesion. GO:0006133 obsolete 5,10-methylenetetrahydrofolate oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006133 5,10-methylenetetrahydrofolate oxidation OBSOLETE. This term was not defined before being made obsolete. GO:0006134 obsolete dihydrobiopterin reduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006134 dihydrobiopterin reduction OBSOLETE. (Was not defined before being made obsolete). GO:0045786 negative regulation of cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045786 down-regulation of progression through cell cycle|negative regulation of progression through cell cycle|negative regulation of cell cycle progression|downregulation of progression through cell cycle|down regulation of progression through cell cycle|inhibition of progression through cell cycle Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle. GO:0045783 obsolete negative regulation of calcium in ER biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045783 negative regulation of calcium in ER OBSOLETE. Any process that reduces the concentration of calcium in the ER. GO:0006131 obsolete dihydrolipoamide reduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006131 dihydrolipoamide reduction OBSOLETE. (Was not defined before being made obsolete). GO:0045784 obsolete positive regulation of calcium in ER biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045784 positive regulation of calcium in ER OBSOLETE. Any process that increases the concentration of calcium in the ER. GO:0006132 obsolete dihydrolipoylprotein reduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006132 dihydrolipoylprotein reduction OBSOLETE. (Was not defined before being made obsolete). GO:0045781 negative regulation of cell budding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045781 downregulation of cell budding|negative regulation of budding|down regulation of cell budding|inhibition of cell budding|down-regulation of cell budding Any process that stops, prevents, or reduces the frequency, rate or extent of cell budding. GO:0045782 positive regulation of cell budding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045782 positive regulation of budding|up regulation of cell budding|upregulation of cell budding|stimulation of cell budding|up-regulation of cell budding|activation of cell budding Any process that activates or increases the frequency, rate or extent of cell budding. GO:0006130 obsolete 6-phosphofructokinase reduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006130 6-phosphofructokinase reduction OBSOLETE. (Was not defined before being made obsolete). GO:0070729 cyclic nucleotide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070729 The directed movement of a cyclic nucleotide, any nucleotide in which phosphate group is in diester linkage to two positions on the sugar residue, into, out of or within a cell. GO:0070727 cellular macromolecule localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070727 cellular macromolecule localisation Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell. GO:0070728 leucine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070728 Leu binding Interacting selectively and non-covalently with 2-amino-4-methylpentanoic acid. GO:0070725 Yb body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070725 A cytoplasmic part that appears as an electron-dense sphere of around 1.5 micron diameter containing Yb protein found in somatic cells of ovary and testis. There are one to two Yb bodies per cell. GO:0070726 cell wall assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070726 The aggregation, arrangement and bonding together of a cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, and most prokaryotic cells. GO:0045789 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045789 GO:0070723 response to cholesterol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070723 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus. GO:0070724 BMP receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070724 bone morphogenetic protein receptor complex A protein complex that acts as a receptor for bone morphogenetic proteins (BMPs); a homo- or heterodimer of type I and/or type II BMP receptor subunits. GO:0070721 ISGF3 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070721 interferon-stimulated gene factor 3 transcription complex A transcription factor complex that consists of a Stat1-Stat2 heterodimer and the IRF9 protein. GO:0055102 lipase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0055102 Stops, prevents or reduces the activity of a lipase, an enzyme that catalyzes of the hydrolysis of a lipid. GO:0021754 facial nucleus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021754 The process whose specific outcome is the progression of the facial nucleus over time, from its formation to the mature structure. GO:0070722 Tle3-Aes complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070722 Grg3b-Grg5 complex A transcriptional repressor complex that consists of a heterodimer of the proteins Tle3 (also known as Grg3b) and Aes (Grg5), which are homologs of the Drosophila groucho gene product. GO:0021755 eurydendroid cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021755 The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature eurydendroid cell. Differentiation includes the processes involved in commitment of a neuroblast to a eurydendroid cell fate. A eurydendroid cell is an efferent neuron found in the cerebellar cortex of teleosts. GO:0055103 ligase regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0055103 Modulates the activity of a ligase. GO:0021756 striatum development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021756 striate nucleus development|neostriatum development The progression of the striatum over time from its initial formation until its mature state. The striatum is a region of the forebrain consisting of the caudate nucleus, putamen and fundus striati. GO:0055104 ligase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0055104 Stops, prevents or reduces the activity of a ligase. GO:0070720 Grb2-SHP-2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070720 GRB2-SHP-2 complex, PDGF stimulated A protein complex that contains the receptor adaptor proteins Grb2 and SHP-2, and is involved signaling via the PDGFR signaling pathway. GO:0055105 ubiquitin-protein transferase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0055105 Stops, prevents or reduces the activity of a ubiquitin-protein transferase. GO:0021757 caudate nucleus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021757 The progression of the caudate nucleus over time from its initial formation until its mature state. The caudate nucleus is the C-shaped structures of the striatum containing input neurons involved with control of voluntary movement in the brain. GO:0021758 putamen development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021758 The progression of the putamen over time from its initial formation until its mature state. The putamen is the lens-shaped basal ganglion involved with control of voluntary movement in the brain. GO:0021759 globus pallidus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021759 pallidum development The progression of the globus pallidus over time from its initial formation until its mature state. The globus pallidus is one of the basal ganglia involved with control of voluntary movement in the brain. GO:0055100 adiponectin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0055100 Interacting selectively and non-covalently with adiponectin, a protein hormone produced by adipose tissue that modulates a number of metabolic processes, including glucose regulation and fatty acid catabolism. GO:0055101 obsolete glycerophospholipase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0055101 glycerophospholipase inhibitor activity OBSOLETE. Stops, prevents or reduces the activity of a glycerophospholipase, an enzyme that catalyzes of the hydrolysis of a glycerophospholipid. GO:0045790 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045790 GO:0045791 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045791 GO:0006108 malate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006108 malate metabolism The chemical reactions and pathways involving malate, the anion of hydroxybutanedioic acid, a chiral hydroxydicarboxylic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle. GO:0006109 regulation of carbohydrate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006109 regulation of carbohydrate metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates. GO:0055117 regulation of cardiac muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055117 Any process that modulates the frequency, rate or extent of cardiac muscle contraction. GO:0006106 fumarate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006106 fumarate metabolism The chemical reactions and pathways involving fumarate, the anion of trans-1,2-ethenedicarboxylic acid, the diastereoisomer of maleate. It is a key intermediate in metabolism and is formed in the TCA cycle from succinate and converted into malate. GO:0006107 oxaloacetate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006107 oxaloacetate metabolism The chemical reactions and pathways involving oxaloacetate, the anion of oxobutanedioic acid, an important intermediate in metabolism, especially as a component of the TCA cycle. GO:0055118 negative regulation of cardiac muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055118 Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle contraction. GO:0021740 principal sensory nucleus of trigeminal nerve development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021740 pontine nucleus development The process whose specific outcome is the progression of the pontine nucleus over time, from its formation to the mature structure. GO:0055119 relaxation of cardiac muscle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055119 The process in which the extent of cardiac muscle contraction is reduced. GO:0021741 spinal trigeminal nucleus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021741 The process whose specific outcome is the progression of the spinal trigeminal nucleus over time, from its formation to the mature structure. GO:0006104 succinyl-CoA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006104 succinyl-CoA metabolism The chemical reactions and pathways involving succinyl-CoA, a compound composed of the monovalent acyl group 3-carboxypropanoyl, derived from succinic acid by loss of one OH group, linked to coenzyme A. GO:0006105 succinate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006105 succinate metabolism The chemical reactions and pathways involving succinate, also known as butanedioate or ethane dicarboxylate, the dianion of succinic acid. Succinate is an important intermediate in metabolism and a component of the TCA cycle. GO:0021742 abducens nucleus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021742 The process whose specific outcome is the progression of the abducens nucleus over time, from its formation to the mature structure. GO:0006102 isocitrate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006102 isocitrate metabolism The chemical reactions and pathways involving isocitrate, the anion of isocitric acid, 1-hydroxy-1,2,3-propanetricarboxylic acid. Isocitrate is an important intermediate in the TCA cycle and the glycoxylate cycle. GO:0045798 negative regulation of chromatin assembly or disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045798 down-regulation of chromatin assembly or disassembly|inhibition of chromatin assembly or disassembly|negative regulation of chromatin assembly/disassembly|down regulation of chromatin assembly or disassembly|downregulation of chromatin assembly or disassembly Any process that stops, prevents, or reduces the frequency, rate or extent of chromatin assembly or disassembly. GO:0045799 positive regulation of chromatin assembly or disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045799 up regulation of chromatin assembly or disassembly|activation of chromatin assembly or disassembly|stimulation of chromatin assembly or disassembly|up-regulation of chromatin assembly or disassembly|upregulation of chromatin assembly or disassembly|positive regulation of chromatin assembly/disassembly Any process that activates or increases the frequency, rate or extent of chromatin assembly or disassembly. GO:0006103 2-oxoglutarate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006103 alpha-ketoglutarate metabolic process|2-ketoglutarate metabolism|2-oxoglutarate metabolism|alpha-ketoglutarate metabolism|2-ketoglutarate metabolic process|alpha-oxoglutarate metabolic process|alpha-oxoglutarate metabolism The chemical reactions and pathways involving oxoglutarate, the dianion of 2-oxoglutaric acid. It is a key constituent of the TCA cycle and a key intermediate in amino-acid metabolism. GO:0006100 obsolete tricarboxylic acid cycle intermediate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006100 citric acid cycle intermediate metabolic process|citric acid cycle intermediate metabolism|TCA intermediate metabolic process|tricarboxylic acid cycle intermediate metabolic process|Krebs cycle intermediate metabolic process|Krebs cycle intermediate metabolism|tricarboxylic acid cycle intermediate metabolism|TCA intermediate metabolism OBSOLETE. The chemical reactions and pathways involving intermediates of the tricarboxylic acid cycle. GO:0045796 negative regulation of intestinal cholesterol absorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045796 downregulation of cholesterol absorption|down regulation of cholesterol absorption|inhibition of cholesterol absorption|down-regulation of cholesterol absorption Any process that stops, prevents, or reduces the frequency, rate or extent of uptake of cholesterol into the blood by absorption from the intestine. GO:0045797 positive regulation of intestinal cholesterol absorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045797 up regulation of cholesterol absorption|upregulation of cholesterol absorption|stimulation of cholesterol absorption|up-regulation of cholesterol absorption|activation of cholesterol absorption Any process that activates or increases the frequency, rate or extent of uptake of cholesterol into the blood by absorption from the intestine. GO:0006101 citrate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006101 citrate metabolism The chemical reactions and pathways involving citrate, 2-hydroxy-1,2,3-propanetricarboyxlate. Citrate is widely distributed in nature and is an important intermediate in the TCA cycle and the glyoxylate cycle. GO:0045794 negative regulation of cell volume biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045794 RVD|cell regulatory volume decrease Any process that decreases cell volume. GO:0045795 positive regulation of cell volume biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045795 Any process that increases cell volume. GO:0045792 negative regulation of cell size biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045792 inhibition of cell size|down regulation of cell size|downregulation of cell size|down-regulation of cell size Any process that reduces cell size. GO:0045793 positive regulation of cell size biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045793 up-regulation of cell size|upregulation of cell size|up regulation of cell size|activation of cell size|stimulation of cell size Any process that increases cell size. GO:0070758 regulation of interleukin-35-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070758 regulation of IL-35-mediated signaling pathway|regulation of interleukin-35-mediated signalling pathway Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-35-mediated binding to a cell surface receptor. GO:0070759 negative regulation of interleukin-35-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070759 negative regulation of interleukin-35-mediated signalling pathway|negative regulation of IL-35-mediated signaling pathway Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-35 binding to a cell surface receptor. GO:0070756 positive regulation of interleukin-35 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070756 upregulation of interleukin-35 production|up regulation of interleukin-35 production|activation of interleukin-35 production|stimulation of interleukin-35 production|positive regulation of interleukin-35 biosynthetic process|positive regulation of IL-35 production|up-regulation of interleukin-35 production Any process that activates or increases the frequency, rate, or extent of interleukin-35 production. GO:0070757 interleukin-35-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070757 interleukin-35-mediated signalling pathway|IL-35-mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-35 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0070754 regulation of interleukin-35 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070754 regulation of interleukin-35 biosynthetic process|regulation of IL-35 production Any process that modulates the frequency, rate, or extent of interleukin-35 production. GO:0055113 epiboly involved in gastrulation with mouth forming second biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055113 The expansion of one cell sheet over other cells involved in deuterostomic gastrulation. GO:0021743 hypoglossal nucleus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021743 The process whose specific outcome is the progression of the hypoglossal nucleus over time, from its formation to the mature structure. GO:0055114 obsolete oxidation-reduction process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055114 oxidoreductase process|oxidation reduction OBSOLETE. A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons. GO:0070755 negative regulation of interleukin-35 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070755 down regulation of interleukin-35 production|downregulation of interleukin-35 production|negative regulation of IL-35 production|down-regulation of interleukin-35 production|negative regulation of interleukin-35 biosynthetic process|inhibition of interleukin-35 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-35 production. GO:0021744 dorsal motor nucleus of vagus nerve development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021744 The process whose specific outcome is the progression of the dorsal motor nucleus of the vagus nerve over time, from its formation to the mature structure. GO:0055115 entry into diapause biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055115 Wikipedia:Diapause The dormancy process that results in entry into diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation. GO:0070752 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0070752 GO:0021745 nucleus ambiguus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021745 The process whose specific outcome is the progression of the nucleus ambiguus over time, from its formation to the mature structure. GO:0070753 interleukin-35 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0070753 IL-35 production|interleukin-35 secretion|interleukin-35 biosynthetic process The appearance of interleukin-35 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0055116 entry into reproductive diapause biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055116 The dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli. GO:0021746 solitary nucleus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021746 The process whose specific outcome is the progression of the solitary nucleus over time, from its formation to the mature structure. GO:0070750 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0070750 GO:0021747 cochlear nucleus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021747 The process whose specific outcome is the progression of the cochlear nucleus over time, from its formation to the mature structure. GO:0055110 involution involved in gastrulation with mouth forming second biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055110 The inturning of an epithelial sheet over the basal surface of an outer layer involved in deuterostomic gastrulation. GO:0070751 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0070751 GO:0021748 dorsal cochlear nucleus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021748 The process whose specific outcome is the progression of the dorsal cochlear nucleus over time, from its formation to the mature structure. GO:0021749 ventral cochlear nucleus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021749 The process whose specific outcome is the progression of the ventral cochlear nucleus over time, from its formation to the mature structure. GO:0055111 ingression involved in gastrulation with mouth forming second biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055111 The migration of individual cells into the embryo involved in deuterostomic gastrulation. GO:0055112 delamination involved in gastrulation with mouth forming second biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055112 The splitting or migration of one epithelial sheet into two involved in the process of deuterostomic gastrulation. GO:0006119 oxidative phosphorylation biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0006119 Wikipedia:Oxidative_phosphorylation respiratory-chain phosphorylation The phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis. GO:0006117 acetaldehyde metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006117 acetaldehyde metabolism|ethanal metabolism|ethanal metabolic process The chemical reactions and pathways involving acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol. GO:0055128 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0055128 GO:0006118 obsolete electron transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006118 oxidized glutathione reduction|protein-disulfide reduction|electron transport|6-phosphofructokinase reduction|electron transfer|other pathways of electron transport|dihydrolipoamide reduction|dihydrobiopterin reduction|dihydrolipoylprotein reduction|dihydropteridine reduction OBSOLETE. The transport of electrons from an electron donor to an electron acceptor. GO:0055129 L-proline biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055129 pyrrolidine-2-carboxylic acid biosynthetic process The chemical reactions and pathways resulting in the formation of L-proline, an L-enantiomer of a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins. GO:0006115 ethanol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006115 ethanol biosynthesis|ethanol anabolism|ethanol synthesis|ethanol formation The chemical reactions and pathways resulting in the formation of ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation. GO:0021730 trigeminal sensory nucleus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021730 The process whose specific outcome is the progression of the trigeminal sensory nucleus over time, from its formation to the mature structure. GO:0006116 NADH oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006116 NADH dehydrogenation|reduced nicotinamide adenine dinucleotide dehydrogenation|reduced nicotinamide adenine dinucleotide oxidation|reduced NAD dehydrogenation|reduced NAD oxidation|NAD (reduced) dehydrogenation|NAD (reduced) oxidation A metabolic process that results in the oxidation of reduced nicotinamide adenine dinucleotide, NADH, to the oxidized form, NAD. GO:0021731 trigeminal motor nucleus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021731 The process whose specific outcome is the progression of the trigeminal motor nucleus over time, from its formation to the mature structure. GO:0006113 fermentation biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0006113 Wikipedia:Fermentation_(biochemistry)|MetaCyc:FERMENTATION-PWY The anaerobic enzymatic conversion of organic compounds, especially carbohydrates, coupling the oxidation and reduction of NAD/H and the generation of adenosine triphosphate (ATP). GO:0006114 glycerol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006114 glycerol synthesis|glycerol formation|glycerol biosynthesis|glycerol anabolism The chemical reactions and pathways resulting in the formation of glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids. GO:0006111 regulation of gluconeogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006111 regulation of gluconeogenesis involved in cellular glucose homeostasis|regulation of glucose biosynthesis|regulation of glucose biosynthetic process Any process that modulates the frequency, rate or extent of gluconeogenesis, the formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol. GO:0006112 energy reserve metabolic process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0006112 energy reserve metabolism The chemical reactions and pathways by which a cell derives energy from stored compounds such as fats or glycogen. GO:0006110 regulation of glycolytic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006110 regulation of glycolysis involved in cellular glucose homeostasis Any process that modulates the frequency, rate or extent of glycolysis. GO:0070749 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0070749 GO:0070747 interleukin-35 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070747 IL-35R|IL-35 receptor activity Combining with interleukin-35 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0070748 interleukin-35 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070748 interleukin-35 receptor ligand|IL-35 Interacting selectively and non-covalently with the interleukin-35 receptor. GO:0070745 interleukin-35 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070745 IL12A|IL-35 complex|p35|EBI3 A protein complex that is composed of an interleukin-12 alpha subunit (p35, product of the IL12A gene) and an EBI3 subunit and is secreted into the extracellular space. GO:0070746 interleukin-35 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070746 IL-35 binding Interacting selectively and non-covalently with interleukin-35. GO:0021732 midbrain-hindbrain boundary maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021732 isthmus maturation|MHB maturation A developmental process, independent of morphogenetic (shape) change, that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate. GO:0055124 obsolete premature neural plate formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055124 premature neural plate formation OBSOLETE. The formation of the neural plate before the appropriate time. GO:0070743 interleukin-23 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070743 IL12B|IL23A|p19|IL-23 complex|p40 A protein complex that is composed of an interleukin-23 alpha (p19, product of the IL23A gene) and an interleukin-12 beta (p40, product of the IL12B gene) subunit and is secreted into the extracellular space. GO:0055125 obsolete Nic96 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0055125 Nic96 complex OBSOLETE. A protein complex that forms part of the nuclear pore complex, and is required for its correct assembly. In Saccharomyces cerevisiae Nic96 contains Nsp1p, Nup57p, Nup49p, and Nic96p. GO:0021733 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0021733 GO:0070744 interleukin-27 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070744 IL-27 complex|p28|IL27|EBI3 A protein complex that is composed of an interleukin-27p28 subunit (product of the IL27 gene) and an EBI3 subunit and is secreted into the extracellular space. GO:0070741 response to interleukin-6 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070741 response to IL-6 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus. GO:0021734 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0021734 GO:0055126 obsolete Nup82 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0055126 Nup82 complex OBSOLETE. A protein complex that forms part of the nuclear pore complex. It forms a subcomplex with Nup159p and Nsp1p, interacts with Nup116p, and is required for proper localization of Nup116p. In Saccharomyces cerevisiae this complex contains Nup82p, Nsp1p, Nup159p, Nup116p, and Gle2p. GO:0055127 vibrational conductance of sound to the inner ear biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055127 The transmission of vibrations via ossicles to the inner ear. GO:0070742 C2H2 zinc finger domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070742 Interacting selectively and non-covalently with a C2H2-type zinc finger domain of a protein. The C2H2 zinc finger is the classical zinc finger domain, in which two conserved cysteines and histidines co-ordinate a zinc ion. GO:0021735 dentate nucleus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021735 The process whose specific outcome is the progression of the dentate nucleus over time, from its formation to the mature structure. GO:0055120 striated muscle dense body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0055120 A vinculin-containing myofibril attachment structure of striated muscle that connects sarcomeres to the extracellular matrix. In nematode body wall muscle, the dense body performs the dual role of Z-disk and costamere. GO:0021736 globose nucleus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021736 The process whose specific outcome is the progression of the globose nucleus over time, from its formation to the mature structure. GO:0055121 response to high fluence blue light stimulus by blue high-fluence system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055121 response to high fluence blue light|response to high fluence blue light by bhf system Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a high fluence blue light stimulus by the blue high-fluence system. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm. The blue high-fluence system responds to blue light at levels between 100 and 1000 micromols/m2. GO:0070740 tubulin-glutamic acid ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070740 Reactome:R-HSA-8865774|Reactome:R-HSA-8955869 tubulin-glutamate ligase activity|tubulin glutamylase activity Catalysis of the posttranslational transfer of one or more glutamate residues to the gamma-carboxyl group(s) of one or more specific glutamate residues on a tubulin molecule. GO:0021737 emboliform nucleus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021737 The process whose specific outcome is the progression of the emboliform nucleus over time, from its formation to the mature structure. GO:0021738 fastigial nucleus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021738 The process whose specific outcome is the progression of the fastigial nucleus over time, from its formation to the mature structure. GO:0055122 response to very low light intensity stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055122 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low light intensity stimulus. A very low light intensity stimulus is defined as a level of electromagnetic radiation below 0.001 mmol/m2/sec. GO:0055123 digestive system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055123 The process whose specific outcome is the progression of the digestive system over time, from its formation to the mature structure. The digestive system is the entire structure in which digestion takes place. Digestion is all of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. GO:0021739 mesencephalic trigeminal nucleus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021739 The process whose specific outcome is the progression of the mesencephalic trigeminal nucleus over time, from its formation to the mature structure. GO:0021720 superior olivary nucleus formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021720 The process that gives rise to the superior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound. GO:0021729 superior reticular formation development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021729 The process whose specific outcome is the progression of the superior reticular formation over time, from its formation to the mature structure. GO:0055130 D-alanine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055130 (2R)-2-aminopropanoic acid catabolic process The chemical reactions and pathways resulting in the breakdown of D-alanine, the D-enantiomer of the amino acid alanine. GO:0070778 L-aspartate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070778 L-aspartate transport The directed movement of L-aspartate across a membrane. GO:0070779 D-aspartate import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070779 D-aspartate import into cell|D-aspartate uptake|D-aspartate import The directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol. GO:0070776 MOZ/MORF histone acetyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070776 A histone acetyltransferase complex that has histone H3 acetyltransferase and coactivator activities. Subunits of the human complex include MYST3/MOZ, MYST4/MORF, ING5, EAF6 and one of BRPF1, BRD1/BRPF2 and BRPF3. GO:0021721 superior olivary nucleus structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021721 superior olivary nucleus structural organisation The process that contributes to the act of creating the structural organization of the superior olivary nucleus structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound. GO:0070777 D-aspartate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070777 The directed movement of D-aspartate, the D-enantiomer of the anion of (2R)-2-aminobutanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0021722 superior olivary nucleus maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021722 superior olive maturation A developmental process, independent of morphogenetic (shape) change, that is required for the superior olivary nucleus to attain its fully functional state. The superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound. GO:0021723 medullary reticular formation development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021723 rhombencephalic reticular formation development The process whose specific outcome is the progression of the medullary reticular formation over time, from its formation to the mature structure. The medullary reticular formation is a series of brain nuclei located in the medulla oblongata. GO:0070774 phytoceramidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070774 Reactome:R-HSA-428262|MetaCyc:CERAMIDASE-YEAST-RXN|KEGG_REACTION:R06528 Catalysis of the reaction: a phytoceramide + H2O = a fatty acid + phytosphingosine. GO:0070775 H3 histone acetyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070775 H3 HAT complex A multisubunit complex that catalyzes the acetylation of histone H3. GO:0021724 inferior raphe nucleus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021724 inferior central nucleus development|posterior raphe nucleus development The process whose specific outcome is the progression of the inferior raphe nucleus over time, from its formation to the mature structure. GO:0055131 C3HC4-type RING finger domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0055131 Interacting selectively and non-covalently with a C3HC4-type zinc finger domain of a protein. The C3HC4-type zinc finger is a variant of RING finger, is a cysteine-rich domain of 40 to 60 residues that coordinates two zinc ions, and has the consensus sequence: C-X2-C-X(9-39)-C-X(1-3)-H-X(2-3)-C-X2-C-X(4-48)-C-X2-C, where X is any amino acid. Many proteins containing a C3HC4-type RING finger play a key role in the ubiquitination pathway. GO:0021725 superior raphe nucleus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021725 anterior raphe nucleus development|superior central nucleus development The process whose specific outcome is the progression of the superior raphe nucleus over time, from its formation to the mature structure. GO:0070772 PAS complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070772 autophagy-specific phosphatidylinositol 3-kinase complex A class III phosphatidylinositol 3-kinase complex that contains a phosphatidylinositol-3-phosphate 5-kinase subunit (Fab1p in yeast; PIKfyve in mammals), a kinase activator, and a phosphatase, and may also contain additional proteins; it is involved in regulating the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate. In mammals the complex is composed of PIKFYVE, FIG4 and VAC14. In yeast it is composed of Atg18p, Fig4p, Fab1p, Vac14p and Vac7p. GO:0021726 lateral reticular nucleus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021726 The process whose specific outcome is the progression of the lateral reticular nucleus over time, from its formation to the mature structure. GO:0055132 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0055132 GO:0070773 protein-N-terminal glutamine amidohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070773 NtQ-amidase activity Catalysis of the reaction: protein-N-terminal-L-glutamine + H2O = protein-N-terminal-L-glutamate + NH3. This reaction is the deamidation of an N-terminal glutamine residue of a protein. GO:0055133 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0055133 GO:0070770 alphaIIb-beta3 integrin-CD47-FAK complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070770 ITGA2b-ITGB3-CD47-FAK complex A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface antigen CD47 and the kinase FAK. GO:0021727 intermediate reticular formation development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021727 intermediate reticular nucleus development The process whose specific outcome is the progression of the intermediate reticular formation over time, from its formation to the mature structure. GO:0070771 alphaIIb-beta3 integrin-CD47-Src complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070771 ITGA2b-ITGB3-CD47-SRC complex A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface antigen CD47 and the kinase c-Src. GO:0055134 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0055134 GO:0021728 inferior reticular formation development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021728 The process whose specific outcome is the progression of the inferior reticular formation over time, from its formation to the mature structure. GO:0021718 superior olivary nucleus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021718 superior olive development The process whose specific outcome is the progression of the superior olivary nucleus over time, from its formation to the mature structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound. GO:0021719 superior olivary nucleus morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021719 superior olive morphogenesis The process in which the anatomical structure of the superior olivary nucleus is generated and organized. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound. GO:0070769 alphaIIb-beta3 integrin-CIB complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070769 ITGA2B-ITGB3-CIB1 complex A protein complex that consists of an alphaIIb-beta3 integrin complex bound to CIB, a protein that binds calcium as well as the alphaIIb-beta3 integrin. GO:0070767 BRCA1-Rad51 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070767 A protein complex that contains BRCA1 and Rad 51, and is involved in the control of recombination and of genome integrity. GO:0070768 synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Unc13 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070768 Snap25-Syt1-Unc13b-Vamp2-Stx1b2-Stx1a complex|SNARE complex (Snap25, Syt1, Unc13b, Vamp2, Stx1b2, Stx1a) A SNARE complex that contains synaptotagmin, synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, syntaxin1b, and Unc13b (or orthologs thereof). GO:0070765 gamma-secretase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070765 presenilin complex|CD147-gamma-secretase complex (APH-1a, PS-1, PEN-2, NCT variant)|gamma-secretase complex (APH1B, PSEN2, PSENEN, NCSTN)|gamma-secretase complex (APH1A, PSEN2, PSENEN, NCSTN)|PS2 complex|PS1 complex|gamma-secretase complex (APH1B, PSEN1, PSENEN, NCSTN)|gamma-secretase complex (APH1A, PSEN1, PSENEN, NCSTN variant) A protein complex that has aspartic-type endopeptidase activity and contains a presenilin catalytic subunit (either PSEN1 or PSEN2), an APH1 subunit (multiple genes and splice variants exist), nicastrin (NCT), and presenilin enhancer (aka PEN-2 or Psenen), as the core complex. Variants of the complex with different subunit compositions differ in localization and specific substrates. Additionally, variants of the complex exist that contain a additional regulatory subunit as well as the four core subunits; known regulatory subunits include gamma-secretase-activating protein (aka gSAP), TMP1 (aka TMED10), and CD147 antigen (aka basigin). Gamma-secretase cleaves type I transmembrane protein substrates, including the cell surface receptor Notch and the amyloid-beta precursor protein. GO:0021710 cerebellar stellate cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021710 The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar stellate cell. Differentiation includes the processes involved in commitment of a neuroblast to a cerebellar stellate cell fate. A cerebellar stellate cell is an inhibitory GABAergic interneuron found in the cerebellar cortex. GO:0021711 cerebellar unipolar brush cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021711 The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature unipolar brush cell in the cerebellum. Differentiation includes the processes involved in commitment of a neuroblast to a unipolar brush cell fate. A unipolar brush cell is a glutamatergic interneuron found in the cerebellar cortex. GO:0070766 endobrevin-synaptobrevin 2-alpha-SNAP-NSF-syntaxin-4 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070766 SNARE complex (Stx4, Napa, Vamp3, Nsf, Vamp2)|Stx4-Napa-Vamp3-Nsf-Vamp2 complex A SNARE complex that contains endobrevin (VAMP8), synaptobrevin 2 (VAMP2), alpha-SNAP, NSF, and syntaxin 4 (or orthologs thereof). GO:0021712 candelabrum cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021712 The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature candelabrum cell. Differentiation includes the processes involved in commitment of a neuroblast to a candelabrum cell fate. A candelabrum cell is an inhibitory GABAergic interneuron found in the cerebellar cortex. GO:0070763 Delta1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070763 Delta1 homodimer complex A protein complex that consists of homodimer of the Notch ligand Delta1. GO:0021713 inferior olivary nucleus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021713 inferior olive development The process whose specific outcome is the progression of the inferior olivary nucleus over time, from its formation to the mature structure. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements. GO:0070764 gamma-secretase-Delta1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070764 A protein complex that is formed by the association of the Notch ligand Delta1 with the gamma-secretase complex. GO:0021714 inferior olivary nucleus morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021714 inferior olive morphogenesis The process in which the anatomical structure of the inferior olivary nucleus is generated and organized. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements. GO:0070761 pre-snoRNP complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070761 pre-small nucleolar ribonucleoprotein complex A ribonucleoprotein complex that contains a precursor small nucleolar RNA (pre-snoRNA) and associated proteins, and forms during small nucleolar ribonucleoprotein complex (snoRNP) assembly. Pre-snoRNP complexes may contain proteins not found in the corresponding mature snoRNP complexes. GO:0021715 inferior olivary nucleus formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021715 inferior olive biosynthesis|inferior olive formation The process that gives rise to the inferior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements. GO:0070762 nuclear pore transmembrane ring biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070762 NDC1 complex|NDC1 subcomplex A subcomplex of the nuclear pore complex (NPC) that spans the nuclear membrane and anchors the NPC to the nuclear envelope. In S. cerevisiae, the transmembrane ring is composed of Pom152p, Pom34p, and Ndc1p. In vertebrates, it is composed of Gp210, Ndc1, and Pom121. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometime referred to as the Ndc1 complex. GO:0021716 inferior olivary nucleus structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021716 inferior olive structural organization|inferior olivary nucleus structural organisation The process that contributes to the act of creating the structural organization of the inferior olivary nucleus structure. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements. GO:0021717 inferior olivary nucleus maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021717 inferior olive maturation A developmental process, independent of morphogenetic (shape) change, that is required for the inferior olivary nucleus to attain its fully functional state. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements. GO:0070760 positive regulation of interleukin-35-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070760 positive regulation of interleukin-35-mediated signalling pathway|positive regulation of IL-35-mediated signaling pathway Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-35 binding to a cell surface receptor. CHEBI:71993 flavonol(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71993 GO:0031182 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031182 GO:0031183 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031183 GO:0031180 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031180 GO:0031181 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031181 GO:0031188 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031188 GO:0031189 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031189 GO:0031186 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031186 GO:0031187 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031187 GO:0031184 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031184 GO:0031185 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031185 GO:0031171 ferricrocin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031171 ferricrocin synthesis|ferricrocin formation|ferricrocin biosynthetic process, peptide modification|ferricrocin biosynthesis|ferricrocin biosynthetic process, peptide formation|ferricrocin anabolism The chemical reactions and pathways resulting in the formation of ferricrocin, a cyclic hexapeptide siderophore with the structure Gly-Ser-Gly-(N5-acetyl-N5-hydroxyornithine)3. GO:0031172 ornithine N5-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031172 MetaCyc:RXN-11128|RHEA:41508 L-ornithine 5-monooxygenase activity Catalysis of the reaction: L-ornithine + O2 + H+ = N5-hydroxy-L-ornithine + H2O. GO:0031170 ferricrocin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031170 ferricrocin metabolism The chemical reactions and pathways involving ferricrocin, a cyclic hexapeptide siderophore with the structure Gly-Ser-Gly-(N5-acetyl-N5-hydroxyornithine)3. GO:0031179 peptide modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031179 The covalent alteration of one or more amino acid residues within a peptide, resulting in a change in the properties of that peptide. GO:0031177 phosphopantetheine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031177 Interacting selectively and non-covalently with phosphopantetheine, the vitamin pantetheine 4'-(dihydrogen phosphate). GO:0031178 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031178 GO:0031175 neuron projection development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031175 neurite growth|neurite outgrowth|neurite formation|neurite development|neurite biosynthesis The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). GO:0031176 endo-1,4-beta-xylanase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031176 EC:3.2.1.8|MetaCyc:3.2.1.8-RXN beta-1,4-xylanase activity|endo-(1->4)-beta-xylanase(1->4)-beta-xylan 4-xylanohydrolase activity|1,4-beta-xylan xylanohydrolase activity|endo-beta-1,4-xylanase activity|endo-1,4-beta-D-xylanase activity|beta-xylanase activity|xylanase|beta-D-xylanase activity|endo-(1,4)-beta-xylanase(1,4)-beta-xylan 4-xylanohydrolase activity|1,4-beta-D-xylan xylanohydrolase activity|beta-1,4-xylan xylanohydrolase activity|endo-1,4-xylanase activity Catalysis of the endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans. GO:0031173 otolith mineralization completed early in development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031173 otoconium mineralization|otoconia mineralization The formation of otoliths during embryogenesis with completion in early postembryonic development. Formation occurs by precipitation of specific crystal forms of calcium carbonate around an organic core of extracellular matrix proteins. Otoconia (otoliths) are small (~10 micron) dense extracellular particles present in the otolith end organs of the vertebrate inner ear. GO:0031174 lifelong otolith mineralization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031174 The formation and growth of otoliths throughout the life of the organism. Otoliths are the large extracellular ear-stones of the fish inner ear, produced by precipitation of specific crystal forms of calcium carbonate on organic matrices. The otolith enlarges throughout the life of the fish, as layers of calcium carbonate are added. GO:0031160 spore wall biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031160 spore coat The specialized envelope lying outside the cell membrane of a spore. GO:0031161 phosphatidylinositol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031161 phosphatidylinositol degradation|PtdIns catabolic process|phosphatidylinositol catabolism|phosphatidylinositol breakdown|PtdIns catabolism The chemical reactions and pathways resulting in the breakdown of phosphatidylinositol, any glycophospholipid with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol. GO:0031168 ferrichrome metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031168 ferrichrome metabolism The chemical reactions and pathways involving a ferrichrome. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine. GO:0031169 ferrichrome biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031169 ferrichrome anabolism|ferrichrome synthesis|ferrichrome formation|ferrichrome biosynthetic process, peptide modification|ferrichrome biosynthetic process, peptide formation|ferrichrome biosynthesis The chemical reactions and pathways resulting in the formation of a ferrichrome. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine. GO:0031166 integral component of vacuolar membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031166 integral to vacuolar membrane The component of the vacuolar membrane consisting of gene products and protein complexes that have some part that penetrates at least one leaflet of the membrane bilayer. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. GO:0031167 rRNA methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031167 The posttranscriptional addition of methyl groups to specific residues in an rRNA molecule. GO:0031164 contractile vacuolar membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031164 contractile vacuole membrane The lipid bilayer surrounding the contractile vacuole. GO:0031165 integral component of contractile vacuolar membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031165 integral to contractile vacuolar membrane The component of the contractile vacuolar membrane consisting of gene products that have some part that penetrates at least one leaflet of the membrane bilayer. This component includes gene products that are buried in the bilayer with no exposure outside the bilayer. GO:0031162 sulfur incorporation into metallo-sulfur cluster biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031162 sulphur incorporation into metallo-sulphur cluster The incorporation of exogenous sulfur into a metallo-sulfur cluster. GO:0031163 metallo-sulfur cluster assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031163 metallo-sulfur cluster biosynthesis|metallo-sulphur cluster assembly|metal-sulfur cluster assembly The incorporation of a metal and exogenous sulfur into a metallo-sulfur cluster. GO:0031159 positive regulation of aggregate size involved in sorocarp development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031159 stimulation of aggregate size|activation of aggregate size|up-regulation of aggregate size|up regulation of aggregate size|upregulation of aggregate size Any process that increases the size of the aggregate formed during sorocarp formation. GO:0045700 regulation of spermatid nuclear differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045700 Any process that modulates the frequency, rate or extent of spermatid nuclear differentiation. GO:0045707 regulation of adult salivary gland boundary specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045707 regulation of adult salivary gland determination Any process that modulates the frequency, rate or extent of salivary gland determination in an adult organism. GO:0031150 sorocarp stalk development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031150 stalk formation|stalk development|sorophore development The process whose specific outcome is the progression of the sorocarp stalk over time, from its formation to the mature structure. The sorocarp stalk is a tubular structure that consists of cellulose-covered cells stacked on top of each other and surrounded by an acellular stalk tube composed of cellulose and glycoprotein. An example of this process is found in Dictyostelium discoideum. GO:0045708 regulation of larval salivary gland boundary specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045708 regulation of larval salivary gland determination Any process that modulates the frequency, rate or extent of salivary gland determination in a larval organism. GO:0045705 negative regulation of salivary gland boundary specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045705 negative regulation of salivary gland determination|down-regulation of salivary gland determination|downregulation of salivary gland determination|down regulation of salivary gland determination|inhibition of salivary gland determination Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination. GO:0045706 positive regulation of salivary gland boundary specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045706 stimulation of salivary gland determination|up-regulation of salivary gland determination|activation of salivary gland determination|positive regulation of salivary gland determination|up regulation of salivary gland determination|upregulation of salivary gland determination Any process that activates or increases the frequency, rate or extent of salivary gland determination. GO:0045703 ketoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045703 Catalysis of the reduction of a ketone group to form the corresponding alcohol. GO:0045704 regulation of salivary gland boundary specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045704 regulation of salivary gland determination Any process that modulates the frequency, rate or extent of salivary gland determination. GO:0045701 negative regulation of spermatid nuclear differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045701 inhibition of spermatid nuclear differentiation|down regulation of spermatid nuclear differentiation|downregulation of spermatid nuclear differentiation|down-regulation of spermatid nuclear differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of spermatid nuclear differentiation. GO:0045702 positive regulation of spermatid nuclear differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045702 up-regulation of spermatid nuclear differentiation|upregulation of spermatid nuclear differentiation|up regulation of spermatid nuclear differentiation|activation of spermatid nuclear differentiation|stimulation of spermatid nuclear differentiation Any process that activates or increases the frequency, rate or extent of spermatid nuclear differentiation. GO:0031157 regulation of aggregate size involved in sorocarp development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031157 regulation of aggregation during fruiting body biosynthesis|regulation of aggregation during fruiting body formation Any process that modulates the size of the aggregate formed during sorocarp formation. GO:0031158 negative regulation of aggregate size involved in sorocarp development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031158 down-regulation of aggregate size|downregulation of aggregate size|down regulation of aggregate size|inhibition of aggregate size Any process that decreases the size of the aggregate formed during sorocarp formation. GO:0031155 regulation of reproductive fruiting body development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031155 regulation of fruiting body formation Any process that modulates the frequency, rate or extent of reproductive fruiting body development. GO:0031156 regulation of sorocarp development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031156 regulation of fruiting body formation|regulation of fruiting body development Any process that modulates the frequency, rate or extent of sorocarp development. An example of this process is found in Dictyostelium discoideum. GO:0031153 slug development involved in sorocarp development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031153 slug development during fruiting body development|pseudoplasmodium biosynthesis|migratory slug development during sorocarp development|pseudoplasmodium formation|slug development during sorocarp development|standing slug development during sorocarp development The process whose specific outcome is the progression of the slug over time, from its formation to the mature structure. Slug development begins when the aggregate rises upwards to form a finger-shaped structure and ends when culmination begins. Slug development begins after aggregation and ends before culmination in sorocarp development. GO:0031154 culmination involved in sorocarp development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031154 culminant development|culmination during sorocarp development|culmination during fruiting body development The process whose specific outcome is the progression of the culminant over time, from its formation to the mature structure. Culmination begins with a morphogenetic change of the finger-like or migratory slug giving rise to an organized structure containing a stalk and a sorus. This process is the final stage of sorocarp development. GO:0031151 histone methyltransferase activity (H3-K79 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031151 histone methylase activity (H3-K79 specific)|histone lysine N-methyltransferase activity (H3-K79 specific) Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 79) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 79). This reaction is the addition of a methyl group onto lysine at position 79 of the histone H3 protein. GO:0045709 negative regulation of adult salivary gland boundary specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045709 negative regulation of adult salivary gland determination|down-regulation of adult salivary gland determination|downregulation of adult salivary gland determination|down regulation of adult salivary gland determination|inhibition of adult salivary gland determination Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination in an adult organism. GO:0031152 aggregation involved in sorocarp development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031152 aggregate development involved in sorocarp development|aggregation during fruiting body development The process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug. GO:0031148 DIF-1 biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031148 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one anabolism|1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one synthesis|1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one formation|1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one biosynthesis|1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one biosynthetic process|DIF-1 biosynthesis The chemical reactions and pathways resulting in the formation of 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one, also known as DIF-1, differentiation-inducing factor-1. DIF-1 is a secreted chlorinated molecule that controls cell fate during development of Dictyostelium cells. GO:0031149 sorocarp stalk cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031149 stalk cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a sorocarp stalk cell, any of the cellulose-covered cells that form the stalk of a sorocarp. An example of this process is found in Dictyostelium discoideum. GO:0045710 negative regulation of larval salivary gland boundary specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045710 inhibition of larval salivary gland determination|down regulation of larval salivary gland determination|downregulation of larval salivary gland determination|negative regulation of larval salivary gland determination|down-regulation of larval salivary gland determination Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination in a larval organism. GO:0045711 positive regulation of adult salivary gland boundary specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045711 upregulation of adult salivary gland determination|stimulation of adult salivary gland determination|up-regulation of adult salivary gland determination|activation of adult salivary gland determination|positive regulation of adult salivary gland determination|up regulation of adult salivary gland determination Any process that activates or increases the frequency, rate or extent of salivary gland determination in an adult organism. GO:0006188 IMP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006188 IMP anabolism|IMP synthesis|IMP biosynthesis|IMP formation The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate. GO:0006189 'de novo' IMP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006189 'de novo' IMP synthesis|'de novo' IMP formation|'de novo' IMP biosynthesis|'de novo' purine biosynthetic process|'de novo' purine biosynthesis|'de novo' IMP anabolism The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate, by the stepwise assembly of a purine ring on ribose 5-phosphate. GO:0006186 dGDP phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006186 The process of introducing a phosphate group into dGDP, deoxyguanosine diphosphate, to produce dGTP. GO:0006187 dGTP biosynthetic process from dGDP biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006187 dGTP anabolism from dGDP|dGTP synthesis from dGDP|dGTP formation from dGDP The chemical reactions and pathways resulting in the formation of dGTP, deoxyguanosine triphosphate (2'-deoxyguanosine 5'-triphosphate) from other compounds, including gGDP, deoxyguanosine diphosphate. GO:0006184 obsolete GTP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006184 GTP catabolism|GTP degradation|GTP breakdown|GTP hydrolysis OBSOLETE. The chemical reactions and pathways resulting in the breakdown of GTP, guanosine triphosphate. GO:0006185 dGDP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006185 dGDP anabolism|dGDP synthesis|dGDP formation|dGDP biosynthesis The chemical reactions and pathways resulting in the formation of dGDP, deoxyguanosine diphosphate, (2'-deoxyguanosine 5'-diphosphate). GO:0006193 ITP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006193 ITP hydrolysis|ITP degradation|ITP catabolism|ITP breakdown The chemical reactions and pathways resulting in the breakdown of ITP, inosine (5'-)triphosphate. GO:0045718 obsolete negative regulation of flagellum assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045718 downregulation of flagellum assembly|down regulation of flagellum assembly|negative regulation of flagellum biogenesis|inhibition of flagellum assembly|negative regulation of flagella assembly|down-regulation of flagellum assembly|negative regulation of flagellum assembly OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a flagellum. GO:0045719 negative regulation of glycogen biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045719 down regulation of glycogen biosynthetic process|downregulation of glycogen biosynthetic process|negative regulation of glycogen anabolism|negative regulation of glycogen synthesis|negative regulation of glycogen formation|down-regulation of glycogen biosynthetic process|negative regulation of glycogen biosynthesis|inhibition of glycogen biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen. GO:0006194 dIDP phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006194 The process of introducing a phosphate group into dIDP, deoxyinosine diphosphate, to produce dITP. GO:0045716 obsolete positive regulation of low-density lipoprotein particle receptor biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045716 positive regulation of low-density lipoprotein receptor biosynthesis|activation of low-density lipoprotein receptor biosynthetic process|stimulation of low-density lipoprotein receptor biosynthetic process|positive regulation of low-density lipoprotein receptor biosynthetic process|up-regulation of low-density lipoprotein receptor biosynthetic process|upregulation of low-density lipoprotein receptor biosynthetic process|positive regulation of low-density lipoprotein receptor anabolism|positive regulation of low-density lipoprotein receptor synthesis|positive regulation of low-density lipoprotein receptor formation|up regulation of low-density lipoprotein receptor biosynthetic process OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of low-density lipoprotein receptors. GO:0006191 deoxyinosine salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006191 Any process that generates deoxyinosine from derivatives of it, without de novo synthesis. GO:0045717 negative regulation of fatty acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045717 inhibition of fatty acid biosynthetic process|down regulation of fatty acid biosynthetic process|downregulation of fatty acid biosynthetic process|negative regulation of fatty acid anabolism|negative regulation of fatty acid synthesis|negative regulation of fatty acid biosynthesis|down-regulation of fatty acid biosynthetic process|negative regulation of fatty acid formation Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids. GO:0006192 IDP phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006192 The process of introducing a phosphate group into IDP, inosine (5'-)diphosphate, to produce ITP. GO:0045714 obsolete regulation of low-density lipoprotein particle receptor biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045714 regulation of low-density lipoprotein receptor formation|regulation of low-density lipoprotein receptor biosynthetic process|regulation of LDLr biosynthesis|regulation of LDLr biosynthetic process|regulation of low-density lipoprotein receptor biosynthesis|regulation of low-density lipoprotein receptor anabolism|regulation of low-density lipoprotein receptor synthesis OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of low-density lipoprotein particle receptors. GO:0006190 inosine salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006190 adenine, hypoxanthine and their nucleoside salvage|guanine, xanthine and their nucleoside salvage Any process that generates inosine, hypoxanthine riboside, from derivatives of it without de novo synthesis. GO:0045715 obsolete negative regulation of low-density lipoprotein particle receptor biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045715 down-regulation of low-density lipoprotein receptor biosynthetic process|negative regulation of low-density lipoprotein receptor biosynthesis|inhibition of low-density lipoprotein receptor biosynthetic process|negative regulation of low-density lipoprotein receptor biosynthetic process|negative regulation of low-density lipoprotein receptor anabolism|negative regulation of low-density lipoprotein receptor synthesis|negative regulation of low-density lipoprotein receptor formation|down regulation of low-density lipoprotein receptor biosynthetic process|downregulation of low-density lipoprotein receptor biosynthetic process OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of low-density lipoprotein particle receptors. GO:0045712 positive regulation of larval salivary gland boundary specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045712 up-regulation of larval salivary gland determination|upregulation of larval salivary gland determination|positive regulation of larval salivary gland determination|up regulation of larval salivary gland determination|activation of larval salivary gland determination|stimulation of larval salivary gland determination Any process that activates or increases the frequency, rate or extent of salivary gland determination in a larval organism. GO:0045713 obsolete low-density lipoprotein particle receptor biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045713 low-density lipoprotein receptor biosynthesis|low-density lipoprotein receptor anabolism|low-density lipoprotein receptor biosynthetic process|low-density lipoprotein receptor synthesis|low-density lipoprotein receptor formation|LDLr biosynthetic process|LDLr biosynthesis OBSOLETE. The chemical reactions and pathways resulting in the formation of low-density lipoprotein receptors, cell surface proteins that mediate the endocytosis of low-density lipoprotein particles by cells. GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031146 SCF-dependent proteasomal ubiquitin-dependent protein degradation|SCF-dependent proteasomal ubiquitin-dependent protein catabolism|SCF-dependent proteasomal ubiquitin-dependent protein breakdown The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome. GO:0031147 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031147 DIF-1 metabolic process|1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one metabolism|DIF-1 metabolism The chemical reactions and pathways involving 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one, also known as DIF-1, differentiation-inducing factor-1. DIF-1 is a secreted chlorinated molecule that controls cell fate during development of Dictyostelium cells. GO:0031144 proteasome localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031144 establishment and maintenance of proteasome localization|proteasome localisation Any process in which the proteasome is transported to, or maintained in, a specific location. GO:0031145 anaphase-promoting complex-dependent catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein degradation|anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolism|degradation of cyclin|anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein breakdown|anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process|cyclin catabolism|cyclin degradation|APC-dependent proteasomal ubiquitin-dependent protein catabolism|cyclin breakdown|negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation|cyclin catabolic process|APC-dependent proteasomal ubiquitin-dependent protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome. GO:0031142 induction of conjugation upon nitrogen starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031142 The process in which a cell initiates conjugation with cellular fusion upon nitrogen starvation. GO:0031143 pseudopodium biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0031143 Wikipedia:Pseudopod pseudopod A temporary protrusion or retractile process of a cell, associated with flowing movements of the protoplasm, and serving for locomotion and feeding. GO:0031140 induction of conjugation upon nutrient starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031140 The process in which a cell initiates conjugation with cellular fusion upon starvation for one or more nutrients. GO:0031141 induction of conjugation upon carbon starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031141 The process in which a cell initiates conjugation with cellular fusion upon carbon starvation. GO:0031139 positive regulation of conjugation with cellular fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031139 upregulation of conjugation with cellular fusion|stimulation of conjugation with cellular fusion|activation of conjugation with cellular fusion|up-regulation of conjugation with cellular fusion|up regulation of conjugation with cellular fusion Any process that increases the rate or frequency of conjugation with cellular fusion. GO:0031137 regulation of conjugation with cellular fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031137 Any process that modulates the rate or frequency of conjugation with cellular fusion. GO:0031138 negative regulation of conjugation with cellular fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031138 down-regulation of conjugation with cellular fusion|downregulation of conjugation with cellular fusion|down regulation of conjugation with cellular fusion|inhibition of conjugation with cellular fusion Any process that decreases the rate or frequency of conjugation with cellular fusion. GO:0045721 negative regulation of gluconeogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045721 downregulation of gluconeogenesis|down-regulation of gluconeogenesis|inhibition of gluconeogenesis|down regulation of gluconeogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of gluconeogenesis. GO:0045722 positive regulation of gluconeogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045722 up regulation of gluconeogenesis|activation of gluconeogenesis|stimulation of gluconeogenesis|up-regulation of gluconeogenesis|upregulation of gluconeogenesis Any process that activates or increases the frequency, rate or extent of gluconeogenesis. GO:0006199 obsolete ADP reduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006199 ADP reduction OBSOLETE. (Was not defined before being made obsolete). GO:0045720 negative regulation of integrin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045720 negative regulation of integrin synthesis|down regulation of integrin biosynthetic process|negative regulation of integrin formation|downregulation of integrin biosynthetic process|negative regulation of integrin biosynthesis|down-regulation of integrin biosynthetic process|inhibition of integrin biosynthetic process|negative regulation of integrin anabolism Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins. GO:0006197 obsolete adenylate deaminase reaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006197 adenylate deaminase reaction OBSOLETE. (Was not defined before being made obsolete). GO:0006198 cAMP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006198 cAMP breakdown|3',5'-cAMP catabolic process|adenosine 3',5'-cyclophosphate catabolic process|cyclic AMP catabolic process|3',5' cAMP catabolism|3',5' cAMP catabolic process|cyclic AMP catabolism|cAMP catabolism|adenosine 3',5'-cyclophosphate catabolism|3',5'-cAMP catabolism|cAMP degradation The chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate). GO:0006195 purine nucleotide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006195 purine nucleotide breakdown|purine nucleotide catabolism|purine nucleotide degradation The chemical reactions and pathways resulting in the breakdown of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. GO:0006196 AMP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006196 AMP catabolism|AMP degradation|AMP breakdown The chemical reactions and pathways resulting in the breakdown of AMP, adenosine monophosphate. GO:0045729 respiratory burst at fertilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045729 oxidative burst at fertilization|metabolic burst at fertilization The phase of elevated metabolic activity, during which oxygen consumption increases, that occurs at fertilization. An enhanced uptake of oxygen leads to the production of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. Capacitation, a necessary prerequisite event to successful fertilization, can be induced by reactive oxygen species in vitro; hydrogen peroxide is used as an extracellular oxidant to cross-link the protective surface envelopes. GO:0045727 positive regulation of translation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045727 positive regulation of protein formation|upregulation of protein biosynthetic process|stimulation of protein biosynthetic process|up-regulation of protein biosynthetic process|activation of protein biosynthetic process|positive regulation of protein biosynthetic process|positive regulation of protein biosynthesis|up regulation of protein biosynthetic process|positive regulation of protein anabolism|positive regulation of protein synthesis Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA. GO:0045728 respiratory burst after phagocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045728 metabolic burst after phagocytosis|oxidative burst after phagocytosis A phase of elevated metabolic activity, during which oxygen consumption increases, that occurs in neutrophils, monocytes, and macrophages shortly after phagocytosing material. An enhanced uptake of oxygen leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals, which play a part in microbiocidal activity. GO:0045725 positive regulation of glycogen biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045725 up-regulation of glycogen biosynthetic process|upregulation of glycogen biosynthetic process|up regulation of glycogen biosynthetic process|activation of glycogen biosynthetic process|positive regulation of glycogen biosynthesis|positive regulation of glycogen anabolism|stimulation of glycogen biosynthetic process|positive regulation of glycogen synthesis|positive regulation of glycogen formation Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen. GO:0045726 positive regulation of integrin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045726 positive regulation of integrin anabolism|upregulation of integrin biosynthetic process|positive regulation of integrin synthesis|positive regulation of integrin formation|up regulation of integrin biosynthetic process|positive regulation of integrin biosynthesis|activation of integrin biosynthetic process|stimulation of integrin biosynthetic process|up-regulation of integrin biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins. GO:0045723 positive regulation of fatty acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045723 up regulation of fatty acid biosynthetic process|activation of fatty acid biosynthetic process|positive regulation of fatty acid biosynthesis|positive regulation of fatty acid anabolism|stimulation of fatty acid biosynthetic process|positive regulation of fatty acid synthesis|positive regulation of fatty acid formation|up-regulation of fatty acid biosynthetic process|upregulation of fatty acid biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids. GO:0045724 positive regulation of cilium assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045724 up regulation of cilium assembly|activation of cilium assembly|stimulation of cilium assembly|up-regulation of cilium assembly|positive regulation of flagellum assembly|positive regulation of flagellum biogenesis|upregulation of cilium assembly Any process that activates or increases the frequency, rate or extent of the formation of a cilium. GO:0031135 negative regulation of conjugation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031135 down regulation of conjugation|downregulation of conjugation|down-regulation of conjugation|inhibition of conjugation Any process that decreases the rate of conjugation. GO:0031136 positive regulation of conjugation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031136 upregulation of conjugation|up regulation of conjugation|activation of conjugation|stimulation of conjugation|up-regulation of conjugation Any process that increases the rate or frequency of conjugation. GO:0031133 regulation of axon diameter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031133 Any process that modulates the rate, direction or extent of axon growth such that the correct diameter is attained and maintained. GO:0031134 sister chromatid biorientation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031134 chromosome biorientation|sister kinetochore biorientation The cell cycle process in which sister chromatids establish stable attachments to microtubules emanating from opposite spindle poles. GO:0031131 reception of an inductive signal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031131 The process in which one cell or group of cells receives, transduces, and responds to a signal generated by another cell or group of cells of different ancestry and developmental potential, such that the recipient cell(s) undergo a developmental change. GO:0031132 serine 3-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031132 RHEA:21596|KEGG_REACTION:R06126|EC:1.1.1.276|Wikipedia:Serine_3-dehydrogenase|MetaCyc:RXN0-2201 L-serine:NADP+ 3-oxidoreductase activity Catalysis of the reaction: L-serine + NADP(+) = L-alpha-formylglycine + 2 H(+) + NADPH. GO:0031130 creation of an inductive signal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031130 The process in which one cell or group of cells sends a signal over a short range to another cell or group of cells of different ancestry and developmental potential, thereby effecting a developmental change in the latter. GO:0031128 developmental induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031128 A developmental process involving two tissues in which one tissue (the inducer) produces a signal that directs cell fate commitment of cells in the second tissue (the responder). GO:0031129 inductive cell-cell signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031129 inductive cell-cell signalling Signaling at short range between cells of different ancestry and developmental potential that results in one cell or group of cells effecting a developmental change in the other. This is often done by secretion of proteins by one cell which affects the neighboring cells and causes them to adopt a certain fate. GO:0031126 sno(s)RNA 3'-end processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031126 sno(s)RNA 3' end processing|sRNA 3'-end processing|snoRNA 3'-end processing Any process involved in forming the mature 3' end of a snoRNA family molecule, also referred to as an sRNA in Archaea. GO:0031127 alpha-(1,2)-fucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031127 alpha-1,2-fucosyltransferase activity|alpha-(1->2)-fucosyltransferase activity Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->2) linkage. GO:0045732 positive regulation of protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045732 activation of protein catabolic process|positive regulation of protein catabolism|stimulation of protein catabolic process|up-regulation of protein catabolic process|upregulation of protein catabolic process|positive regulation of protein degradation|positive regulation of protein breakdown|up regulation of protein catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. GO:0006168 adenine salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006168 adenine salvage pathway|adenine, hypoxanthine and their nucleoside salvage Any process that generates adenine, 6-aminopurine, from derivatives of it without de novo synthesis. GO:0045733 acetate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045733 acetate degradation|acetate breakdown|homoacetate catabolic process|acetate catabolism The chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid. GO:0006169 adenosine salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006169 adenine, hypoxanthine and their nucleoside salvage Any process that generates adenosine, adenine riboside, from derivatives of it without de novo synthesis. GO:0006166 purine ribonucleoside salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006166 MetaCyc:P121-PWY Any process which produces a purine nucleoside from derivatives of it, without de novo synthesis. GO:0045730 respiratory burst biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045730 Wikipedia:Respiratory_burst oxidative burst|metabolic burst A phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. GO:0006167 AMP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006167 AMP synthesis|AMP formation|AMP biosynthesis|AMP anabolism The chemical reactions and pathways resulting in the formation of AMP, adenosine monophosphate. GO:0045731 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045731 GO:0006164 purine nucleotide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006164 MetaCyc:DENOVOPURINE2-PWY purine nucleotide anabolism|purine nucleotide synthesis|purine nucleotide biosynthesis|purine nucleotide formation The chemical reactions and pathways resulting in the formation of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. GO:0006165 nucleoside diphosphate phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006165 The process of introducing a phosphate group into a nucleoside diphosphate to produce a nucleoside triphosphate. GO:0006162 obsolete purine/pyrimidine nucleoside diphosphate reduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006162 purine/pyrimidine nucleoside diphosphate reduction OBSOLETE. (Was not defined before being made obsolete). GO:0006163 purine nucleotide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006163 purine nucleotide metabolism|purine metabolism|purine metabolic process The chemical reactions and pathways involving a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. GO:0006171 cAMP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006171 cAMP anabolism|3',5' cAMP biosynthetic process|cAMP synthesis|3',5' cAMP biosynthesis|cAMP formation|cyclic AMP biosynthesis|cyclic AMP biosynthetic process|cAMP biosynthesis|adenosine 3',5'-cyclophosphate biosynthesis|adenosine 3',5'-cyclophosphate biosynthetic process|3',5'-cAMP biosynthetic process|3',5'-cAMP biosynthesis The chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate). GO:0006172 ADP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006172 ADP synthesis|ADP biosynthesis|ADP formation|ADP anabolism The chemical reactions and pathways resulting in the formation of ADP, adenosine 5'-diphosphate. GO:0045738 negative regulation of DNA repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045738 down regulation of DNA repair|inhibition of DNA repair|down-regulation of DNA repair|downregulation of DNA repair Any process that stops, prevents, or reduces the frequency, rate or extent of DNA repair. GO:0045739 positive regulation of DNA repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045739 upregulation of DNA repair|stimulation of DNA repair|activation of DNA repair|up-regulation of DNA repair|up regulation of DNA repair Any process that activates or increases the frequency, rate or extent of DNA repair. GO:0006170 dAMP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006170 dAMP anabolism|dAMP synthesis|dAMP formation|dAMP biosynthesis The chemical reactions and pathways resulting in the formation of dAMP, deoxyadenosine monophosphate (2'-deoxyadenosine 5'-phosphate). GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045736 Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity. GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045737 upregulation of cyclin-dependent protein kinase activity|positive regulation of cyclin-dependent protein kinase activity|up-regulation of cyclin-dependent protein kinase activity|stimulation of cyclin-dependent protein kinase activity|activation of cyclin-dependent protein kinase activity|positive regulation of CDK activity|up regulation of cyclin-dependent protein kinase activity Any process that activates or increases the frequency, rate or extent of CDK activity. GO:0045734 regulation of acetate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045734 regulation of acetate catabolism|regulation of acetate degradation|regulation of acetate breakdown Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid. GO:0045735 nutrient reservoir activity biolink:MolecularActivity go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0045735 storage protein|yolk protein|storage protein of fat body Functions in the storage of nutritious substrates. GO:0031124 mRNA 3'-end processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031124 mRNA 3' end processing Any process involved in forming the mature 3' end of an mRNA molecule. GO:0031125 rRNA 3'-end processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031125 rRNA 3' end processing Any process involved in forming the mature 3' end of an rRNA molecule. GO:0031122 cytoplasmic microtubule organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031122 cytoplasmic microtubule organisation|cytoplasmic microtubule organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell. GO:0031123 RNA 3'-end processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031123 RNA 3' end processing Any process involved in forming the mature 3' end of an RNA molecule. GO:0031120 snRNA pseudouridine synthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031120 The intramolecular conversion of uridine to pseudouridine in an snRNA molecule. GO:0031121 equatorial microtubule organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031121 equatorial microtubule organisation|equatorial microtubule organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins at the midpoint of a cell. GO:0021790 chemorepulsion of branchiomotor neuron axon in branchial arch mesenchyme biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021790 negative chemotaxis of branchiomotor neuron axon in branchial arch mesenchyme The process in which a branchiomotor neuron growth cone in the branchial arch mesenchyme is directed to a specific target site in the branchial arch mesenchyme in response to a repulsive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx. GO:0021791 chemoattraction of branchiomotor neuron axon in branchial arch mesenchyme biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021791 positive chemotaxis of branchiomotor neuron axon in branchial arch mesenchyme The process in which a branchiomotor neuron growth cone in the branchial arch mesenchyme is directed to a specific target site in the branchial arch mesenchyme in response to an attractive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx. GO:0031119 tRNA pseudouridine synthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031119 The intramolecular conversion of uridine to pseudouridine in a tRNA molecule. GO:0021792 chemoattraction of branchiomotor axon biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021792 positive chemotaxis of branchiomotor axon The process in which a branchiomotor neuron growth cone is directed to a specific target site in response to an attractive chemical signal. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx. GO:0021793 chemorepulsion of branchiomotor axon biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021793 negative chemotaxis of branchiomotor axon The process in which a branchiomotor neuron growth cone is directed to a specific target site in response to a repulsive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx. GO:0031117 positive regulation of microtubule depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031117 upregulation of microtubule depolymerization|microtubule destabilization|stimulation of microtubule depolymerization|positive regulation of microtubule catastrophe|positive regulation of microtubule disassembly|up-regulation of microtubule depolymerization|activation of microtubule depolymerization|up regulation of microtubule depolymerization Any process that activates or increases the frequency, rate or extent of microtubule depolymerization. GO:0021794 thalamus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021794 The process in which the thalamus changes over time, from its initial formation to its mature state. GO:0021795 cerebral cortex cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021795 The orderly movement of cells from one site to another in the cerebral cortex. GO:0031118 rRNA pseudouridine synthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031118 The intramolecular conversion of uridine to pseudouridine in an rRNA molecule. GO:0031115 negative regulation of microtubule polymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031115 inhibition of microtubule polymerization|down-regulation of microtubule polymerization|downregulation of microtubule polymerization|down regulation of microtubule polymerization Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization. GO:0021796 cerebral cortex regionalization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021796 cerebral cortex arealization|cerebral cortex pattern formation|cerebral cortex pattern biosynthesis The regionalization process that results in the creation of areas within the cerebral cortex that will direct the behavior of cell migration and differentiation as the cortex develops. GO:0031116 positive regulation of microtubule polymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031116 upregulation of microtubule polymerization|stimulation of microtubule polymerization|up-regulation of microtubule polymerization|activation of microtubule polymerization|up regulation of microtubule polymerization Any process that activates or increases the frequency, rate or extent of microtubule polymerization. GO:0021797 forebrain anterior/posterior pattern specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021797 forebrain anterior-posterior pattern specification The creation of specific areas of progenitor domains along the anterior-posterior axis of the developing forebrain. GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045743 positive regulation of FGF receptor signaling pathway|upregulation of fibroblast growth factor receptor signaling pathway|positive regulation of FGFR signaling pathway|up regulation of fibroblast growth factor receptor signaling pathway|activation of fibroblast growth factor receptor signaling pathway|stimulation of fibroblast growth factor receptor signaling pathway|positive regulation of FGF receptor signalling pathway|up-regulation of fibroblast growth factor receptor signaling pathway Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity. GO:0006179 guanosine salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006179 guanine, xanthine and their nucleoside salvage Any process that generates guanosine, guanine riboside, from derivatives of it without de novo synthesis. GO:0045744 negative regulation of G protein-coupled receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045744 negative regulation of G protein coupled receptor protein signaling pathway|down regulation of G-protein coupled receptor protein signaling pathway|inhibition of G-protein coupled receptor protein signaling pathway|negative regulation of GPCR protein signalling pathway|negative regulation of G-protein coupled receptor protein signalling pathway|down-regulation of G-protein coupled receptor protein signaling pathway|negative regulation of G-protein coupled receptor protein signaling pathway|negative regulation of G-protein-coupled receptor protein signalling pathway|negative regulation of GPCR protein signaling pathway|negative regulation of G protein coupled receptor protein signalling pathway|downregulation of G-protein coupled receptor protein signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway. GO:0045741 positive regulation of epidermal growth factor-activated receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045741 upregulation of epidermal growth factor receptor activity|positive regulation of epidermal growth factor receptor activity|up regulation of epidermal growth factor receptor activity|positive regulation of EGFR activity|activation of epidermal growth factor receptor activity|stimulation of epidermal growth factor receptor activity|positive regulation of EGF receptor activity|up-regulation of epidermal growth factor receptor activity Any process that activates or increases the frequency, rate or extent of EGF-activated receptor activity. GO:0006177 GMP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006177 GMP biosynthesis|GMP anabolism|GMP synthesis|GMP formation The chemical reactions and pathways resulting in the formation of GMP, guanosine monophosphate. GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045742 positive regulation of EGFR signaling pathway|up regulation of epidermal growth factor receptor signaling pathway|upregulation of epidermal growth factor receptor signaling pathway|stimulation of epidermal growth factor receptor signaling pathway|activation of epidermal growth factor receptor signaling pathway|up-regulation of epidermal growth factor receptor signaling pathway|positive regulation of EGF receptor signalling pathway|positive regulation of EGF receptor signaling pathway Any process that activates or increases the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity. GO:0006178 guanine salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006178 guanine, xanthine and their nucleoside salvage Any process that generates guanine, 2-amino-6-hydroxypurine, from derivatives of it without de novo synthesis. GO:0006175 dATP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006175 dATP biosynthesis|dATP anabolism|dATP synthesis|dATP formation The chemical reactions and pathways resulting in the formation of dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate). GO:0045740 positive regulation of DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045740 up regulation of DNA replication|activation of DNA replication|stimulation of DNA replication|up-regulation of DNA replication|upregulation of DNA replication Any process that activates or increases the frequency, rate or extent of DNA replication. GO:0006176 dATP biosynthetic process from ADP biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006176 dATP formation from ADP|dATP synthesis from ADP|dATP anabolism from ADP The chemical reactions and pathways resulting in the formation of dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate) from other compounds, including ADP, adenosine diphosphate. GO:0006173 dADP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006173 dADP biosynthesis|dADP anabolism|dADP synthesis|dADP formation The chemical reactions and pathways resulting in the formation of dADP, deoxyadenosine diphosphate (2'-deoxyadenosine 5'-diphosphate). GO:0006174 dADP phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006174 The process of introducing a phosphate group into dADP, deoxyadenosine diphosphate, to produce dATP. GO:0006182 cGMP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006182 cGMP biosynthesis|cGMP anabolism|cGMP synthesis|cGMP formation The chemical reactions and pathways resulting in the formation of cyclic GMP, guanosine 3',5'-phosphate. GO:0006183 GTP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006183 GTP biosynthesis|GTP anabolism|GTP synthesis|GTP formation The chemical reactions and pathways resulting in the formation of GTP, guanosine triphosphate. GO:0006180 deoxyguanosine salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006180 Any process that generates deoxyguanosine from derivatives of it, without de novo synthesis. GO:0045749 obsolete negative regulation of S phase of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045749 down regulation of S phase of mitotic cell cycle|downregulation of S phase of mitotic cell cycle|down-regulation of S phase of mitotic cell cycle|negative regulation of S phase of mitotic cell cycle|inhibition of S phase of mitotic cell cycle|negative regulation of S-phase of mitotic cell cycle OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of S phase of mitotic cell cycle activity. GO:0006181 dGMP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006181 dGMP biosynthesis|dGMP anabolism|dGMP synthesis|dGMP formation The chemical reactions and pathways resulting in the formation of dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate). GO:0045747 positive regulation of Notch signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045747 up-regulation of Notch signaling pathway|positive regulation of N signalling pathway|upregulation of Notch signaling pathway|positive regulation of Notch signalling pathway|up regulation of Notch signaling pathway|activation of Notch signaling pathway|stimulation of Notch signaling pathway|positive regulation of N signaling pathway Any process that activates or increases the frequency, rate or extent of the Notch signaling pathway. GO:0045748 positive regulation of R8 cell spacing in compound eye biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045748 upregulation of R8 spacing|stimulation of R8 spacing|positive regulation of R8 spacing|activation of R8 spacing|up-regulation of R8 spacing|up regulation of R8 spacing Any process that activates or enforces the correct R8 cell spacing in a compound eye. GO:0045745 positive regulation of G protein-coupled receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045745 positive regulation of GPCR protein signalling pathway|positive regulation of G-protein coupled receptor protein signalling pathway|upregulation of G-protein coupled receptor protein signaling pathway|positive regulation of G protein coupled receptor protein signaling pathway|stimulation of G-protein coupled receptor protein signaling pathway|positive regulation of G-protein-coupled receptor protein signaling pathway|up-regulation of G-protein coupled receptor protein signaling pathway|activation of G-protein coupled receptor protein signaling pathway|positive regulation of G-protein-coupled receptor protein signalling pathway|positive regulation of G protein coupled receptor protein signalling pathway|positive regulation of G-protein coupled receptor protein signaling pathway|up regulation of G-protein coupled receptor protein signaling pathway|positive regulation of GPCR protein signaling pathway Any process that activates or increases the frequency, rate or extent of G protein-coupled receptor signaling pathway activity. GO:0045746 negative regulation of Notch signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045746 negative regulation of N signaling pathway|negative regulation of Notch signalling pathway|down regulation of Notch signaling pathway|downregulation of Notch signaling pathway|down-regulation of Notch signaling pathway|negative regulation of N signalling pathway|inhibition of Notch signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway. GO:0021798 forebrain dorsal/ventral pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021798 forebrain dorsal-ventral pattern formation|forebrain dorsoventral pattern formation The formation of specific regional progenitor domains along the dorsal-ventral axis in the developing forebrain. GO:0031113 regulation of microtubule polymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031113 Any process that modulates the frequency, rate or extent of microtubule polymerization. GO:0031114 regulation of microtubule depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031114 regulation of microtubule disassembly Any process that modulates the frequency, rate or extent of microtubule depolymerization. GO:0021799 cerebral cortex radially oriented cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021799 The migration of cells in the developing cerebral cortex in which cells move from the ventricular and/or subventricular zone toward the surface of the brain. GO:0031111 negative regulation of microtubule polymerization or depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031111 downregulation of microtubule polymerization or depolymerization|down regulation of microtubule polymerization or depolymerization|inhibition of microtubule polymerization or depolymerization|down-regulation of microtubule polymerization or depolymerization Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization or depolymerization. GO:0031112 positive regulation of microtubule polymerization or depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031112 up regulation of microtubule polymerization or depolymerization|upregulation of microtubule polymerization or depolymerization|stimulation of microtubule polymerization or depolymerization|up-regulation of microtubule polymerization or depolymerization|activation of microtubule polymerization or depolymerization Any process that activates or increases the frequency, rate or extent of microtubule polymerization or depolymerization. GO:0031110 regulation of microtubule polymerization or depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031110 Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule. CHEBI:46951 3-(2,3-dihydroxyphenyl)propanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46951 CHEBI:22985 calcium molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22985 CHEBI:46952 oxazinane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46952 CHEBI:22986 calcium ionophore biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22986 CHEBI:46953 alpha-D-galactoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46953 CHEBI:46954 thiazinane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46954 CHEBI:22984 calcium atom biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_22984 CHEBI:46955 anthracenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46955 CHEBI:32304 2-cis,4-trans-xanthoxin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32304 CHEBI:4917 eugenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_4917 GO:0080076 caffeoyl CoA:S-adenosyl-L-methionine O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080076 Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a caffeoyl CoA molecule. GO:0080077 trihydroxyferuloyl spermidine:S-adenosyl-L-methionine O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080077 Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a trihydroxyferuloyl spermidine molecule. GO:0080078 tricaffeoyl spermidine:S-adenosyl-L-methionine O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080078 Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a tricaffeoyl spermidine molecule. GO:0080079 cellobiose glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080079 MetaCyc:RXN-10773 cellobiose glucohydrolase activity Catalysis of the reaction: cellobiose + H2O = 2 D-glucose. GO:0080072 spermidine:sinapoyl CoA N-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080072 Catalysis of the transfer of a sinapoyl group to a nitrogen atom on the spermidine molecule. GO:0080073 spermidine:coumaroyl CoA N-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080073 Catalysis of the transfer of a coumaroyl group to a nitrogen atom on the spermidine molecule. GO:0080074 spermidine:caffeoyl CoA N-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080074 Catalysis of the transfer of a caffeoyl group to a nitrogen atom on the spermidine molecule. GO:0080075 spermidine:feruloyl CoA N-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080075 Catalysis of the transfer of a feruloyl group to a nitrogen atom on the spermidine molecule. GO:0080070 8-methylthiooctyl-desulfoglucosinolate sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080070 MetaCyc:RXNQT-4333 Catalysis of the reaction: 8-methylthiooctyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 8-methylthiooctyl-glucosinolate + adenosine 3',5'-bisphosphate. CHEBI:4911 etoposide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_4911 GO:0080071 indol-3-yl-methyl-desulfoglucosinolate sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080071 MetaCyc:RXN-1443 Catalysis of the reaction: indol-3-yl-methyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = indol-3-yl-methyl-glucosinolate + adenosine 3',5'-bisphosphate. CHEBI:46957 3-(2-hydroxyphenyl)propanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46957 CHEBI:46959 N-acylazetidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46959 CHEBI:22990 camalexin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_22990 CHEBI:46940 indanes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46940 CHEBI:46941 oxane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46941 CHEBI:46942 oxanes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46942 GO:0080069 7-methylthioheptyl-desulfoglucosinolate sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080069 MetaCyc:RXNQT-4332 Catalysis of the reaction: 7-methylthioheptyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 7-methylthioheptyl-glucosinolate + adenosine 3',5'-bisphosphate. GO:0080065 4-alpha-methyl-delta7-sterol oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080065 4-alpha-methyl-delta7-sterol-4alpha-methyl oxidase activity A lipid oxidation process proceeding through a series of three successive monooxygenations of the alpha methyl group on the C4 carbon (CH3 to CH2OH to CHO to COOH) and resulting in this overall reaction: 4-alpha-methyl-delta7-sterol + 3 NADPH + 3 H+ + 3 O2 = 4-alpha-carboxy,delta7-sterol + 3 NADP+ + 3 H2O. GO:0080066 3-methylthiopropyl-desulfoglucosinolate sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080066 MetaCyc:RXN-2209 Catalysis of the reaction: 3-methylthiopropyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 3-methylthiopropyl-glucosinolate + adenosine 3',5'-bisphosphate. GO:0080067 4-methylthiobutyl-desulfoglucosinolate sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080067 MetaCyc:RXNQT-4329 Catalysis of the reaction: 4-methylthiobutyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 4-methylthiobutyl-glucosinolate + adenosine 3',5'-bisphosphate. GO:0080068 5-methylthiopentyl-desulfoglucosinolate sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080068 MetaCyc:RXNQT-4330 Catalysis of the reaction: 5-methylthiopentyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 5-methylthiopentyl-glucosinolate + adenosine 3',5'-bisphosphate. GO:0080061 indole-3-acetonitrile nitrilase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080061 MetaCyc:RXN-1404|RHEA:45776|EC:3.5.5.1 Catalysis of the reaction: indole-3-acetonitrile + 2 H2O = indole-3-acetic acid + NH3. GO:0080062 cytokinin 9-beta-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080062 KEGG_REACTION:R08369 Catalysis of the reaction: 6-alkylaminopurine + UDP-D-glucose = 6-alkylamino-9-beta-D-glucosylpurine + H+ + UDP. This reaction is an N-glucosylation event. GO:0080063 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0080063 GO:0080064 4,4-dimethyl-9beta,19-cyclopropylsterol oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080064 4,4-dimethyl-9beta,19-cyclopropylsterol-4alpha-methyl oxidase activity A lipid oxidation process proceeding through a series of three successive monooxygenations of the alpha methyl group on the C4 carbon (CH3 to CH2OH to CHO to COOH) and resulting in this overall reaction: 4,4-dimethyl-9beta,19-cyclopropylsterol + 3 NADPH + 3 H+ + 3 O2 = 4-alpha-carboxy, 4-beta-methyl-9beta,19-cyclopropylsterol + 3 NADP+ + 3 H2O. UBERON:0003161 dorsal ocellus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003161 ocelli|ocellus|dorsal ocelli A simple visual organ of insects[GO]. Two ocelli appear on the vertical and one on the frontal plate[FBbt]. The multi-tissue structure that is located on the top of the head, composed of the corneal lens, pigment cell, rhabdoms and synaptic plexus[HAO]. Two evolutionary distinct ocellus types exist [2]: dorsal ocelli (or simply 'ocelli'), found in most insects, and lateral ocelli (or stemmata), which are found in the larvae of some insect orders. They are structurally and functionally very different. Simple eyes of other animals, e.g. cnidarians may also be referred to as 'ocelli', but again the structure and anatomy of these eyes is quite distinct from those of the dorsal ocelli of insects[Wikipedia]. GO:0080060 integument development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080060 The process whose specific outcome is the progression of the integument over time, from its formation to the mature structure. Integument is one of the layers of tissue that usually covers the ovule, enveloping the nucellus and forming the micropyle at the apex. CHEBI:22998 canadine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_22998 CHEBI:22961 butenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22961 GO:0080098 L-tyrosine:pyruvate aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080098 EC:2.6.1.58|MetaCyc:RXN3O-4157 Catalysis of the reaction: L-tyrosine + pyruvate = (4-hydroxyphenyl)pyruvate + L-alanine. CHEBI:71938 9-ribosyl-trans-zeatin 5'-triphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71938 GO:0080099 L-methionine:2-oxoglutarate aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080099 L-methionine:alpha-ketoglutarate aminotransferase activity Catalysis of the reaction: L-methionine + 2-oxoglutarate = 4-methylthio-2-oxobutyrate + L-glutamate. GO:0080094 response to trehalose-6-phosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080094 response to trehalose-6-phosphate stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose-6-phosphate stimulus. GO:0080095 phosphatidylethanolamine-sterol O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080095 Catalysis of the reaction: a phosphatidylethanolamine + a sterol = a sterol ester + a lysophosphatidylethanolamine. GO:0080096 phosphatidate-sterol O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080096 Catalysis of the reaction: a phosphatidate + a sterol = a sterol ester + a lysophosphatidate. GO:0080097 L-tryptophan:pyruvate aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080097 RHEA:27587|MetaCyc:RXN-10139|EC:2.6.1.28 Catalysis of the reaction: L-tryptophan + pyruvate = 3-(indol-3-yl)pyruvate + L-alanine. GO:0080090 regulation of primary metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080090 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. GO:0080091 regulation of raffinose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080091 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving raffinose. GO:0080092 regulation of pollen tube growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080092 Any process that modulates the frequency, rate or extent of pollen tube growth. GO:0080093 regulation of photorespiration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080093 Any process that modulates the rate, frequency or extent of photorespiration. Photorespiration is a light-dependent catabolic process occurring concomitantly with photosynthesis in plants (especially C3 plants) whereby dioxygen (O2) is consumed and carbon dioxide (CO2) is evolved. CHEBI:22967 butyn-1-ols biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22967 CHEBI:22968 butynal biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22968 CHEBI:22965 butanamides biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22965 CHEBI:46939 indolyl carboxylate ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46939 CHEBI:22970 butynediol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22970 CHEBI:22975 cadinane sesquiterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22975 CHEBI:46920 N-methylpiperazine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46920 CHEBI:71944 aldehydic acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71944 CHEBI:4903 17alpha-ethynylestradiol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_4903 CHEBI:71947 tyrocidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71947 CHEBI:71948 tyrocidine B biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71948 GO:0080087 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0080087 CHEBI:71949 tyrocidine C biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71949 GO:0080088 spermidine hydroxycinnamate conjugate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080088 The chemical reactions and pathways resulting in the formation of spermidine hydroxycinnamate conjugates. GO:0080089 sinapoyl spermidine:sinapoyl CoA N-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080089 Catalysis of the transfer of a sinapoyl group to a nitrogen atom on a sinapoyl spermidine molecule resulting in the formation of a disinapoyl spermidine derivative. GO:0080083 beta-gentiobiose beta-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080083 Catalysis of the hydrolysis of glucosidic link in beta-gentiobiose. UBERON:0003142 prepupa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003142 An organism at the prepupal stage. The prepupal stage is a life stage interposed between the larval and the pupal stages in insects that undergo a complete metamorphosis. The start of the pre-pupal stage is marked by pupariation, and the end is marked by pupation GO:0080084 5S rDNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080084 Interacting selectively and non-covalently with the 5S rDNA sequence encoding ribosomal 5S rRNA, which is individually transcribed by RNA polymerase III, rather than by RNA polymerase I, in species where it exists. UBERON:0003143 pupa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003143 pupae|aurelia|chrysalis|chrysalides An organism at the pupal stage. A life cycle stage of holometabolous insects in which the organism is a pupa and starts with the larval-pupal apolysis and ends with pupal-adult apolysis. GO:0080085 signal recognition particle, chloroplast targeting biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0080085 A complex consisting of a protein and RNA component which binds the signal sequence of some proteins and facilitates their export to the chloroplast. GO:0080086 stamen filament development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080086 filament development The process whose specific outcome is the progression of the filament over time, from its formation to the mature structure. Filament is the stalk of a stamen. GO:0080080 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0080080 GO:0080081 4-methylumbelliferyl-beta-D-glucopyranoside beta-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080081 Catalysis of the hydrolysis of glucosidic link in 4-methylumbelliferyl-beta-D-glucopyranoside. GO:0080082 esculin beta-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080082 Catalysis of the hydrolysis of glucosidic link in esculin. CHEBI:22976 cadinene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22976 CHEBI:71950 tyrocidine D biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71950 CHEBI:46911 L-ornithinium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46911 CHEBI:71959 3-amino-5-hydroxybenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71959 CHEBI:46912 ornithinium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46912 CHEBI:46913 ornithinium(2+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46913 CHEBI:46914 L-ornithinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46914 CHEBI:22944 butanediols biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22944 CHEBI:46915 sarcosinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46915 CHEBI:71963 5-amino-5-deoxy-3-dehydroshikimic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71963 CHEBI:71964 UDP-alpha-D-kanosamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71964 CHEBI:71965 UDP-3-keto-alpha-D-glucose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71965 CHEBI:22950 butan-4-olide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22950 CHEBI:46900 cholesteryl octadec-9-enoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46900 CHEBI:22951 butanone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22951 CHEBI:71968 hydroxyflavonoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71968 GO:0031094 platelet dense tubular network biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0031094 A network of membrane-bounded compartments found in blood platelets, where they regulate platelet activation by sequestering or releasing calcium. The dense tubular network exists as thin elongated membranes in resting platelets, and undergoes a major ultrastructural change, to a rounded vesicular form, upon addition of thrombin. GO:0031095 platelet dense tubular network membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031095 The lipid bilayer surrounding the platelet dense tubular network. GO:0031092 platelet alpha granule membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031092 platelet alpha-granule membrane The lipid bilayer surrounding the platelet alpha granule. GO:0031093 platelet alpha granule lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031093 platelet alpha-granule lumen The volume enclosed by the membrane of the platelet alpha granule. GO:0031090 organelle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031090 NIF_Subcellular:sao830981606 intracellular membrane A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle. GO:0031091 platelet alpha granule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031091 Wikipedia:Platelet_alpha-granule platelet alpha-granule A secretory organelle found in blood platelets, which is unique in that it exhibits further compartmentalization and acquires its protein content via two distinct mechanisms: (1) biosynthesis predominantly at the megakaryocyte (MK) level (with some vestigial platelet synthesis) (e.g. platelet factor 4) and (2) endocytosis and pinocytosis at both the MK and circulating platelet levels (e.g. fibrinogen (Fg) and IgG). CHEBI:46903 cholesteryl octadeca-9,12-dienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46903 CHEBI:22954 butanoyl-CoAs biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22954 CHEBI:46904 oxalate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46904 GO:0031098 stress-activated protein kinase signaling cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031098 JNK signaling pathway|SAPK signaling pathway|stress-activated protein kinase signaling pathway|JNK signalling pathway|stress-activated protein kinase signalling pathway|SAPK signalling pathway A series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays one or more of the signals. CHEBI:46905 (R)-pantothenic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46905 GO:0031099 regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031099 Wikipedia:Regeneration_(biology) The regrowth of a lost or destroyed body part, such as an organ or tissue. This process may occur via renewal, repair, and/or growth alone (i.e. increase in size or mass). GO:0031096 platelet dense tubular network lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031096 The volume enclosed by the membranes of the platelet dense tubular network. CHEBI:22958 butenedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22958 GO:0031097 medial cortex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031097 medial ring A medial cortical band overlaying the nucleus which acts as a landmark for contractile ring positioning and plays a role in cell cycle regulation. CHEBI:22959 butenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22959 GO:0031083 BLOC-1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031083 A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. Many of the protein subunits are conserved between mouse and human; the mouse complex contains the Pallidin, Muted, Cappuccino, Dysbindin, Snapin, BLOS1, BLOS2, AND BLOS3 proteins. GO:0031084 BLOC-2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031084 A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. The human complex contains the Hps3, Hps5, and Hps6 proteins; the mouse complex contains ru2 and ru. GO:0031081 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031081 CHEBI:22929 bromoalkane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22929 GO:0031082 BLOC complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0031082 BLOC-1 related complex Any of several protein complexes required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes, platelet dense granules, and other related organelles; acronym for biogenesis of lysosomal-related organelles complex. GO:0031080 nuclear pore outer ring biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031080 Nup107-160 complex|Nup84 complex|Nup107-120 complex A subcomplex of the nuclear pore complex (NPC) that forms the outer rings of the core scaffold, a lattice-like structure that gives the NPC its shape and strength. In S. cerevisiae, the two outer rings each contain multiple copies of the following proteins: Nup133p, Nup120p, Nup145Cp, Nup85p, Nup84p, Seh1p, and Sec13p. In vertebrates, the two outer rings each contain multiple copies of the following proteins: Nup133, Nup160, Nup96, Nup75, Nup107, Seh1, Sec13, Nup43, Nup37, and ALADIN. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometimes referred to as the Nup84 complex (S. cerevisiae) or the Nup107-160 complex (vertebrates). UBERON:0003194 imaginal disc-derived wing vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003194 GO:0031089 platelet dense granule lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031089 The volume enclosed by the membrane of the platelet dense granule. CHEBI:22921 brassinosteroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22921 CHEBI:22927 bromine atom biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_22927 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031087 deadenylation-independent decapping of nuclear mRNA|deadenylylation-independent decapping Cleavage of the 5'-cap of a nuclear-transcribed mRNA that is independent of poly(A) tail shortening. CHEBI:22928 bromine molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22928 GO:0031088 platelet dense granule membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031088 The lipid bilayer surrounding the platelet dense granule. GO:0031085 BLOC-3 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031085 A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. The human complex contains the Hps1 and Hps4 proteins. GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031086 deadenylylation-independent mRNA decay|nuclear mRNA catabolic process, deadenylation-independent decay|mRNA catabolic process, deadenylation-independent|mRNA catabolism, deadenylation-independent|mRNA catabolism, deadenylation-independent decay|deadenylation-independent mRNA decay|mRNA breakdown, deadenylation-independent decay|mRNA degradation, deadenylation-independent decay|mRNA catabolic process, deadenylylation-independent|mRNA catabolism, deadenylylation-independent A pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of steps that is independent of deadenylation, but requires decapping followed by transcript decay, and that can regulate mRNA stability. CHEBI:22926 bromohydrocarbon biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22926 CHEBI:71981 beta-D-glucosylsphingosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71981 CHEBI:71982 C20 sphingosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71982 CHEBI:71983 C20 sphingosine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71983 CHEBI:71984 C20 dihydroceramide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71984 CHEBI:71985 C20 phytoceramide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71985 CHEBI:22930 bromoamino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22930 CHEBI:81308 allocholic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_81308 CHEBI:71986 C20 ceramide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71986 CHEBI:71989 ortho ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71989 GO:0031072 heat shock protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031072 Interacting selectively and non-covalently with a heat shock protein, any protein synthesized or activated in response to heat shock. GO:0031073 cholesterol 26-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031073 Catalysis of the hydroxylation of cholesterol at position 26 of the side chain, to produce 26-hydroxycholesterol. GO:0031070 intronic snoRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031070 The biogenesis of a snoRNA molecule which resides within, and is processed from, the intron of a pre-mRNA. GO:0031071 cysteine desulfurase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031071 EC:2.8.1.7|RHEA:43892|Reactome:R-HSA-1362408|Reactome:R-HSA-947514 SufS|NIFS|IscS|cysteine desulfurylase activity|L-cysteine:enzyme cysteine sulfurtransferase activity Catalysis of the reaction: L-cysteine + [enzyme]-cysteine = L-alanine + [enzyme]-S-sulfanylcysteine. GO:0031078 histone deacetylase activity (H3-K14 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031078 Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 14) + H2O = histone H3 L-lysine (position 14) + acetate. This reaction represents the removal of an acetyl group from lysine at position 14 of the histone H3 protein. GO:0031079 obsolete picornain 3C activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031079 foot-and-mouth protease 3C activity|poliovirus proteinase 3C|3C protease activity|rhinovirus proteinase 3C|foot-and-mouth-disease virus proteinase 3C|protease 3C|picornain 3C activity|tomato ringspot nepovirus 3C-related protease|hepatitis A virus 3C proteinase activity|rhinovirus protease 3C activity|poliovirus protease 3C activity|cysteine proteinase 3C|picornavirus endopeptidase 3C activity|coxsackievirus 3C proteinase activity|3C proteinase activity OBSOLETE. Catalysis of the selective cleavage of GlnGly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly. CHEBI:22933 bromophenylalanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22933 GO:0031076 embryonic camera-type eye development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031076 embryonic eye development The process occurring during the embryonic phase whose specific outcome is the progression of the eye over time, from its formation to the mature structure. GO:0031077 post-embryonic camera-type eye development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031077 post-embryonic camera-style eye development The process occurring during the post-embryonic phase whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. CHEBI:22939 butanals biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22939 GO:0031074 nucleocytoplasmic transport complex biolink:CellularComponent go-plus gocheck_do_not_annotate|goslim_pir http://purl.obolibrary.org/obo/GO_0031074 nucleocytoplasmic shuttling complex Any complex that acts to move proteins or RNAs into or out of the nucleus through nuclear pores. GO:0031075 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031075 CHEBI:71980 N-retinylidene-N-retinylethanolamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71980 GO:0070670 response to interleukin-4 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070670 response to IL-4 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-4 stimulus. GO:0021707 cerebellar granule cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021707 The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar granule cell. Differentiation includes the processes involved in commitment of a neuroblast to a granule cell fate. A granule cell is a glutamatergic interneuron found in the cerebellar cortex. GO:0021708 Lugaro cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021708 The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature Lugaro cell. Differentiation includes the processes involved in commitment of a neuroblast to a Lugaro cell fate. A Lugaro cell is an inhibitory GABAergic interneuron found in the cerebellar cortex. GO:0055030 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0055030 GO:0021709 cerebellar basket cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021709 The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar basket cell. Differentiation includes the processes involved in commitment of a neuroblast to a cerebellar basket cell fate. A cerebellar basket cell is an inhibitory GABAergic interneuron found in the cerebellar cortex. CHEBI:32387 alpha-linolenate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32387 GO:0055031 gamma-tubulin large complex, equatorial microtubule organizing center biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0055031 gamma-tubulin large complex, eMTOC|gamma-tubulin large complex, equatorial microtubule organizing centre A complex of gamma tubulin and associated proteins thought to be formed by multimerization of gamma-tubulin small complexes located at equatorial microtubule organizing centers. CHEBI:32389 all-cis-octadeca-6,9,12,15-tetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32389 GO:0070679 inositol 1,4,5 trisphosphate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070679 IP3 binding|InsP3 binding Interacting selectively and non-covalently with inositol 1,4,5 trisphosphate. CHEBI:4999 fenchone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_4999 GO:0055036 virion membrane biolink:CellularComponent go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0055036 The lipid bilayer surrounding a virion. GO:0070677 rRNA (cytosine-2'-O-)-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070677 Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methylcytosine. GO:0055037 recycling endosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0055037 endosomal recycling compartment|endosome recycling compartment|ERC An organelle consisting of a network of tubules that functions in targeting molecules, such as receptors transporters and lipids, to the plasma membrane. GO:0021700 developmental maturation biolink:BiologicalProcess go-plus goslim_generic|goslim_chembl http://purl.obolibrary.org/obo/GO_0021700 A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state. GO:0070678 preprotein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070678 unprocessed protein binding Interacting selectively and non-covalently with a preprotein, the unprocessed form of a protein destined to undergo co- or post-translational processing. GO:0055038 recycling endosome membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0055038 The lipid bilayer surrounding a recycling endosome. GO:0070675 hypoxanthine oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070675 Schardinger enzyme activity|hypoxanthine:O2 oxidoreductase activity|hypoxanthine:oxygen oxidoreductase activity|hypoxanthine-xanthine oxidase activity|xanthine oxidoreductase activity|hypoxanthine:O(2) oxidoreductase activity|schardinger enzyme Catalysis of the reaction: hypoxanthine + H2O + O2 = xanthine + H2O2. GO:0021701 cerebellar Golgi cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021701 The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Golgi cell. Differentiation includes the processes involved in commitment of a neuroblast to a Golgi cell fate. A cerebellar Golgi cell is an inhibitory GABAergic interneuron found in the cerebellar cortex. GO:0070676 intralumenal vesicle formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070676 endosome membrane budding The invagination of the endosome membrane and resulting formation of a vesicle within the lumen of the endosome. GO:0055039 trichocyst biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0055039 Wikipedia:Trichocyst A crystalline exocytotic organelle composed of small, acidic proteins existing primarily as disulphide-linked dimers. The trichocyst is an organelle that releases long filamentous proteins that capture predators in net-like structures, to slow them down when the cell is disturbed. The protein is nontoxic and shaped like a long, striated, fibrous shaft. GO:0021702 cerebellar Purkinje cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021702 The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Purkinje cell. Differentiation includes the processes involved in commitment of a neuroblast to a Purkinje cell fate. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem. GO:0055032 gamma-tubulin large complex, spindle pole body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0055032 A complex of gamma tubulin and associated proteins thought to be formed by multimerization of gamma-tubulin small complexes located in the spindle pole body. GO:0070673 response to interleukin-18 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070673 response to IL-18 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-18 stimulus. GO:0021703 locus ceruleus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021703 locus caeruleus development|locus coeruleus development The process whose specific outcome is the progression of the locus ceruleus over time, from its formation to the mature structure. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic. GO:0070674 hypoxanthine dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070674 NAD-hypoxanthine dehydrogenase activity|hypoxanthine/NAD(+) oxidoreductase activity|hypoxanthine:NAD+ oxidoreductase activity|hypoxanthine-NAD oxidoreductase activity|hypoxanthine/NAD+ oxidoreductase activity|hypoxanthine oxidoreductase activity Catalysis of the reaction: hypoxanthine + NAD+ + H2O = xanthine + NADH + H+. GO:0021704 locus ceruleus morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021704 The process in which the anatomical structure of the locus ceruleus is generated and organized. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic. GO:0055033 gamma-tubulin large complex, interphase microtubule organizing center biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0055033 gamma-tubulin large complex, iMTOC|gamma-tubulin large complex, interphase microtubule organizing centre A complex of gamma tubulin and associated proteins thought to be formed by multimerization of gamma-tubulin small complexes located at interphase microtubule organizing centers. CHEBI:32381 dec-9-enoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32381 CHEBI:32382 (R)-mandelate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32382 GO:0021705 locus ceruleus formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021705 The process that gives rise to the locus ceruleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic. GO:0055034 Bolwig's organ development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055034 The process whose specific outcome is the progression of the Bolwig's organ over time, from its formation to the mature structure. The larval eye in Drosophila is a relatively simple sensory system composed of Bolwig's organs: two clusters, each composed of 12 photoreceptor cells from which axons extend in a single fascicle to the brain. GO:0070671 response to interleukin-12 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070671 response to IL-12 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-12 stimulus. GO:0055035 plastid thylakoid membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0055035 The lipid bilayer membrane of any thylakoid within a plastid. CHEBI:32383 6-hydroxyhexanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32383 GO:0021706 locus ceruleus maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021706 A developmental process, independent of morphogenetic (shape) change, that is required for the locus ceruleus to attain its fully functional state. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic. GO:0070672 response to interleukin-15 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070672 response to IL-15 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-15 stimulus. CHEBI:32395 arachidonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32395 CHEBI:32396 6-aminohexanoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32396 GO:0055040 periplasmic flagellum biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0055040 Flagellar filaments located in the periplasmic space; characterized in spirochetes, in which they are essential for shape and motility. Composed of a core surrounded by two sheath layers, the flagella rotate to allow migration of the cell through viscous media, which would not be possible using external flagella. GO:0055041 cyclopentanol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0055041 EC:1.1.1.163|RHEA:11728|KEGG_REACTION:R02553|MetaCyc:CYCLOPENTANOL-DEHYDROGENASE-RXN cyclopentanol:NADP+ oxidoreductase activity|cyclopentanol:NAD+ oxidoreductase activity Catalysis of the reaction: cyclopentanol + NAD(+) = cyclopentanone + H(+) + NADH. CHEBI:32398 D-glyceric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32398 GO:0055042 5-valerolactone hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0055042 Catalysis of the reaction: 5-valerolactone + H2O = 5-hydroxyvalerate. GO:0070668 positive regulation of mast cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070668 up regulation of mast cell proliferation|activation of mast cell proliferation|stimulation of mast cell proliferation|up-regulation of mast cell proliferation|upregulation of mast cell proliferation Any process that activates or increases the rate or extent of mast cell proliferation. GO:0070669 response to interleukin-2 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070669 response to IL-2 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-2 stimulus. GO:0070666 regulation of mast cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070666 Any process that modulates the frequency, rate or extent of mast cell proliferation. GO:0055047 generative cell mitosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055047 The process in which the generative cell divides by mitosis to form two haploid cells. These will subsequently differentiate into sperm cells. GO:0070667 negative regulation of mast cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070667 downregulation of mast cell proliferation|down-regulation of mast cell proliferation|inhibition of mast cell proliferation|down regulation of mast cell proliferation Any process that stops, prevents or reduces the rate or extent of mast cell proliferation. GO:0055048 anastral spindle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055048 The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart, in the absence of centrosomes. Formation is initiated by the nucleation of microtubules (MTs) in the vicinity of condensed chromatin. MTs then attach to and congress around the chromatin due to activity of microtubule motors. A bipolar spindle is formed by focusing of the terminal ends of the MT array into spindle poles by molecular motors and cross-linking proteins. GO:0070664 negative regulation of leukocyte proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070664 down regulation of leukocyte proliferation|downregulation of leukocyte proliferation|down-regulation of leukocyte proliferation|inhibition of leukocyte proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte proliferation. GO:0055049 astral spindle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055049 The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart, in the presence of centrosomes. GO:0070665 positive regulation of leukocyte proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070665 upregulation of leukocyte proliferation|up regulation of leukocyte proliferation|activation of leukocyte proliferation|stimulation of leukocyte proliferation|up-regulation of leukocyte proliferation Any process that activates or increases the frequency, rate or extent of leukocyte proliferation. GO:0070662 mast cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070662 The expansion of a mast cell population by cell division. CHEBI:32391 gamma-linolenate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32391 GO:0055043 5-oxovalerate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0055043 Catalysis of the reaction: 5-oxovalerate + NADP+ + H2O = glutarate + NADPH + H+. GO:0070663 regulation of leukocyte proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070663 Any process that modulates the frequency, rate or extent of leukocyte proliferation. GO:0055044 symplast biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0055044 Wikipedia:Symplast The interconnected cell membranes and intracellular regions of a plant. The interconnections occur via the plasmodesmata. CHEBI:32392 (15Z)-tetracosenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32392 GO:0070660 inner ear receptor cell differentiation involved in inner ear sensory epithelium regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070660 Differentiation of new inner ear sensory hair cells to replace those lost or destroyed by injury. GO:0055045 antipodal cell degeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055045 The process in which the antipodal cells undergo programmed cell death. CHEBI:32393 erucate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32393 GO:0055046 microgametogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055046 Wikipedia:Microgametogenesis pollen development from the microspore The process whose specific outcome is the progression of the pollen grain over time, from its formation as the microspore to the mature structure. GO:0070661 leukocyte proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070661 The expansion of a leukocyte population by cell division. GO:0070691 P-TEFb complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070691 Sgv1/Bur2 complex|dimeric positive transcription elongation factor complex b|cyclin-dependent kinase 9 (Cdk9)-cyclin T1 complex|Bur1/Bur2 complex|cyclin-dependent kinase 9 (Cdk9)-cyclin T2 complex A dimeric positive transcription elongation factor complex b that comprises a cyclin-dependent kinase containing the catalytic subunit, Cdk9, and a regulatory subunit, cyclin T. GO:0070692 CTDK-1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070692 trimeric positive transcription elongation factor complex b|Ctk complex|CTDK-I complex|C-terminal domain kinase I complex A positive transcription elongation factor complex that comprises the CDK kinase CTK1 (in budding yeast), Lsk1 (in fission yeast) (corresponding to the Panther PTHR24056:SF39 family), a cyclin and an additional gamma subunit (corresponding to the InterPRO entry IPR024638). GO:0070690 L-threonine catabolic process to acetyl-CoA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070690 MetaCyc:PWY-5436 L-threonine degradation to acetyl-CoA|L-threonine breakdown to acetyl-CoA|L-threonine catabolism to acetyl-CoA|threonine catabolic process to acetyl-CoA The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) into glycine and acetaldehyde, with acetaldehyde being subsequently converted to acetyl-CoA. GO:0080018 anthocyanin 5-O-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080018 Catalysis of the reaction: an anthocyanin + UDP-D-glucose = an anthocyanin-5-O-glucoside + UDP. GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080019 fatty acyl-CoA reductase (alcohol-forming) activity|fatty acyl CoA reductase (alcohol-forming) activity Catalysis of the reaction: a very long chain fatty acyl-CoA + NADPH + H+ = a very long chain primary alcohol + NADP+ + CoA. GO:0080014 thalianol hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080014 EC:1.14.13.-|MetaCyc:RXN-9631 Catalysis of the reaction: a thalianol = a thalian-diol. This reaction is the addition of a hydroxyl group to thalianol ((13R,14R,17E)-podioda-8,17,21-trien-3beta-ol) to create a thalian-diol ((13R,14R,17E)-podioda-8,17,21-trien-3beta,X-diol), where the hydroxyl group may be attached at one of several different available carbons in ring B or C of thalianol, indicated by the X. GO:0080015 sabinene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080015 MetaCyc:RXN-5103|EC:4.2.3.- Catalysis of the reaction: geranyl diphosphate = sabinene + diphosphate. GO:0080016 (-)-E-beta-caryophyllene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080016 RHEA:28294|MetaCyc:RXN-8414|EC:4.2.3.- Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (-)-E-beta-caryophyllene + diphosphate. GO:0080017 alpha-humulene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080017 MetaCyc:RXN-8415|RHEA:31895|EC:4.2.3.- Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = alpha-humulene + diphosphate. GO:0080010 obsolete regulation of oxygen and reactive oxygen species metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080010 regulation of oxygen and reactive oxygen species metabolic process OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving dioxygen (O2), or any of the reactive oxygen species, e.g. superoxide anions (O2-), hydrogen peroxide (H2O2), and hydroxyl radicals (-OH). GO:0080011 baruol synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080011 RHEA:31987|MetaCyc:RXN-9685|EC:5.4.99.- Catalysis of the reaction: (S)-2,3-epoxysqualene = baruol. Baruol is also known as D:B-Friedo-Baccharan-5,21-dien-3-ol. GO:0080012 trihydroxyferuloyl spermidine O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080012 MetaCyc:RXN-11263 N1,N5,N10-tris-(5-hydroxyferuloyl)spermidine O-methyltransferase activity Catalysis of the reaction: trihydroxyferuloyl spermidine + S-adenosyl-L-methionine = dihydroxyferuloyl-sinapoyl spermidine + S-adenosyl-L-homocysteine + H+. GO:0080013 (E,E)-geranyllinalool synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080013 MetaCyc:RXN-10441|RHEA:38155 Catalysis of the reaction: all-trans-geranyl-geranyl diphosphate + H2O = (E,E)-geranyllinalool + diphosphate. GO:0055050 astral spindle assembly involved in male meiosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055050 The aggregation, arrangement and bonding together of a set of components to form the astral spindle in male meiotic cells. CHEBI:32362 heptanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32362 GO:0055051 ATP-binding cassette (ABC) transporter complex, integrated substrate binding biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0055051 A complex for the transport of metabolites out of the cell, consisting of 4 domains: two ATP-binding domains and two membrane spanning domains. In some cases, all 4 domains are contained on 1 polypeptide, while in others one ATP-binding domain and one membrane spanning domain are together on one polypeptide in what is called a half transporter. Two half-transporters come together to form a functional transporter. Transport of the substrate across the membrane is driven by the hydrolysis of ATP. CHEBI:32364 3-dehydroquinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32364 GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0055052 A complex for the transport of metabolites into the cell, consisting of 5 subunits: two ATP-binding subunits, two membrane spanning subunits, and one substrate-binding subunit. In organisms with two membranes, the substrate-binding protein moves freely in the periplasmic space and joins the other subunits only when bound with substrate. In organisms with only one membrane the substrate-binding protein is tethered to the cytoplasmic membrane and associated with the other subunits. Transport of the substrate across the membrane is driven by the hydrolysis of ATP. GO:0055053 mannose:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0055053 mannose:hydrogen symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: mannose + H+ = mannose + H+. CHEBI:32365 heptadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32365 CHEBI:32366 margarate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32366 CHEBI:32368 undecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32368 CHEBI:32369 undecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32369 GO:0055058 symmetric neuroblast division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055058 The process resulting in the physical partitioning and separation of a neuroblast into two equi-potent daughter cells. GO:0070699 type II activin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070699 Interacting selectively and non-covalently with a type II activin receptor. GO:0055059 asymmetric neuroblast division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055059 The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials. GO:0070697 activin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070697 Interacting selectively and non-covalently with an activin receptor. GO:0070698 type I activin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070698 Interacting selectively and non-covalently with a type I activin receptor. GO:0070695 FHF complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070695 A protein complex that is composed of AKTIP/FTS, FAM160A2/p107FHIP, and one or more members of the Hook family of proteins, HOOK1, HOOK2, and HOOK3. The complex is thought to promote vesicle trafficking and/or fusion, and associates with the homotypic vesicular sorting complex (the HOPS complex). GO:0055054 fructose:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0055054 fructose:hydrogen symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fructose + H+ = fructose + H+. GO:0070696 transmembrane receptor protein serine/threonine kinase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070696 Interacting selectively and non-covalently with a receptor that spans a cell membrane and possesses protein serine/threonine kinase activity. GO:0055055 D-glucose:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0055055 D-glucose:hydrogen symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-glucose + H+ = D-glucose + H+. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. D-glucose is the dextrorotatory D-enantiomer of glucose. GO:0070693 P-TEFb-cap methyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070693 P-TEFb-Pcm1 complex|Cdk9-Pcm1 complex A protein complex that is formed by the association of positive transcription elongation factor complex b (P-TEFb) with the mRNA capping methyltransferase. GO:0055056 D-glucose transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0055056 Reactome:R-HSA-8981574|Reactome:R-HSA-8981564|Reactome:R-HSA-5339524|Reactome:R-HSA-8981570|Reactome:R-HSA-429094|Reactome:R-HSA-5632871|Reactome:R-HSA-5632804|Reactome:R-HSA-450095|Reactome:R-HSA-8981553 Enables the transfer of the D-enantiomer of the hexose monosaccharide glucose from one side of a membrane to the other. CHEBI:32360 icosanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32360 GO:0070694 deoxyribonucleoside 5'-monophosphate N-glycosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070694 EC:3.2.2.-|Reactome:R-HSA-8953339 deoxynucleoside 5'-monophosphate N-glycosidase activity Catalysis of the reaction: a deoxyribonucleoside 5'-monophosphate + H2O = deoxyribose 5-monophosphate + a purine or pyrimidine base. GO:0055057 neuroblast division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055057 neuroblast cell division The process resulting in the physical partitioning and separation of a neuroblast into daughter cells. A neuroblast is any cell that will divide and give rise to a neuron. CHEBI:32361 nonanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32361 GO:0070680 asparaginyl-tRNAAsn biosynthesis via transamidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070680 MetaCyc:PWY490-4 A tRNA aminoacylation process in which asparaginyl-tRNAAsn is formed by a tRNA-dependent two-step pathway. In the first step a non-discriminating aspartyl-tRNA synthetase generates the misacylated L-aspartyl-tRNAAsn species, and in the second step it is amidated to the correctly charged L-asparaginyl-tRNAAsn by the heterotrimeric aspartyl-tRNAAsn amidotransferase. GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070681 MetaCyc:PWY-5921 A tRNA aminoacylation process in which glutaminyl-tRNAGln is formed by a tRNA-dependent two-step pathway. In the first step a non-discriminating glutamyl-tRNAGlx synthetase generates the misacylated L-glutamyl-tRNAGln species, and in the second step it is amidated to the correctly charged L-glutaminyl-tRNAGln by a glutamyl-tRNAGln amidotransferase. GO:0080007 S-nitrosoglutathione reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080007 MetaCyc:RXN-10742 Catalysis of the reaction: glutathione N-hydroxysulfenamide + NADH + H+ = S-nitrosoglutathione + NAD+. GO:0080008 Cul4-RING E3 ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0080008 A ubiquitin ligase complex in which a cullin from the Cul4 family and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein. GO:0080009 mRNA methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080009 The posttranscriptional addition of methyl groups to specific residues in an mRNA molecule. GO:0080003 thalianol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080003 thalianol metabolism The chemical reactions and pathways involving the triterpene thalianol. GO:0080004 thalian-diol desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080004 EC:1.14.21.-|MetaCyc:RXN-9637 Catalysis of the reaction: a thalian-diol = a desaturated thalian-diol. This reaction is the introduction of a double bond to a thalian-diol molecule at carbon 15. GO:0080005 photosystem stoichiometry adjustment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080005 Adjustment of Photosystem I/Photosystem II ratio in response to light conditions. The function of photosystem stoichiometry adjustment is to compensate for any deficiency in energy conversion at either photosystem I or photosystem II by increasing the quantity the photosystem that will otherwise become the rate-limiting to overall photosynthesis. GO:0080006 internode patterning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080006 Determines the spacing between two shoot nodes. A shoot node is the region of the shoot where the spikelet, flower, floret, branch, bud and/or leaves are attached. GO:0080001 mucilage extrusion from seed coat biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080001 mucilage release from seed coat|secretion of mucilage from seed coat The process in which seed mucilage expands through hydration and breaks the outer cell wall that encapsulates the whole seed upon imbibition. Mucilage, mainly composed of pectins, is formed during seed development and deposited into the apoplast underneath the outer wall of the seed coat. GO:0080002 UDP-glucose:4-aminobenzoate acylglucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080002 MetaCyc:RXN-6142 UDP-glucose:p-aminobenzoate acylglucosyltransferase activity|UDP-glucose:pABA acylglucosyltransferase activity|UDP-glucose:p-aminobenzoate glucosyltransferase activity Catalysis of the reaction: 4-aminobenzoate + UDP-glucose = p-aminobenzoate-beta-D-glucopyranosyl ester + UDP. GO:0055061 obsolete di-, tri-valent inorganic anion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055061 di-, tri-valent inorganic anion homeostasis OBSOLETE. Any process involved in the maintenance of an internal steady state of divalent or trivalent inorganic anions within an organism or cell. CHEBI:32373 4-coumarate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32373 CHEBI:4986 fatty acid methyl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_4986 GO:0055062 phosphate ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055062 Any process involved in the maintenance of an internal steady state of phosphate ions within an organism or cell. CHEBI:32374 trans-4-coumaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32374 GO:0055063 sulfate ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055063 sulphate ion homeostasis|sulfate homeostasis Any process involved in the maintenance of an internal steady state of sulfate ions within an organism or cell. CHEBI:32375 petroselinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32375 GO:0055064 chloride ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055064 Any process involved in the maintenance of an internal steady state of chloride ions within an organism or cell. CHEBI:32379 cis,cis-muconate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32379 GO:0055060 asymmetric neuroblast division resulting in ganglion mother cell formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055060 Any process resulting in the physical partitioning and separation of a neuroblast into a neuroblast and a ganglion mother cell. GO:0070688 obsolete MLL5-L complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070688 OBSOLETE. A protein complex that can methylate lysine-4 of histone H3 and plays an essential role in retinoic-acid-induced granulopoiesis. MLL5 is the catalytic methyltransferase subunit, and the complex also contains serine/threonine kinase 38 (STK38), protein phosphatase 1 catalytic subunits, the host cell factor-1 N-terminal subunit, beta-actin, and O-GlcNAc transferase; the human genes encoding the subunits are MLL5, STK38, PPP1CA, PPP1CB, PPP1CC, HCFC1, ACTB and OGT, respectively. GO:0055069 zinc ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055069 zinc homeostasis Any process involved in the maintenance of an internal steady state of zinc ions within an organism or cell. GO:0070689 L-threonine catabolic process to propionate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070689 MetaCyc:PWY-5437 L-threonine degradation to propionate|L-threonine breakdown to propionate|L-threonine catabolism to propionate|threonine catabolic process to propionate The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form the compound propionate. GO:0070686 macropinocytic cup membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070686 crown membrane The portion of the plasma membrane surrounding a macropinocytic cup. GO:0070687 macropinocytic cup cytoskeleton biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070687 crown cytoskeleton The part of the cortical actin cytoskeleton that forms part of a macropinocytic cup. GO:0070684 seminal clot liquefaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070684 semen liquefaction The reproductive process in which coagulated semen becomes liquid following ejaculation, allowing the progressive release of motile spermatozoa. GO:0055065 metal ion homeostasis biolink:BiologicalProcess go-plus goslim_pombe http://purl.obolibrary.org/obo/GO_0055065 Any process involved in the maintenance of an internal steady state of metal ions within an organism or cell. GO:0055066 obsolete di-, tri-valent inorganic cation homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055066 di-, tri-valent inorganic cation homeostasis OBSOLETE. Any process involved in the maintenance of an internal steady state of divalent or trivalent cations within an organism or cell. GO:0070685 macropinocytic cup biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070685 crown A cell projection that forms at the site of macropinocytosis, a form of endocytosis that results in the uptake of relatively large amounts of extracellular fluid. The macropinocytic cup membrane selectively excludes certain proteins, such as H36 or PM4C4 in Dictyostelium, and the underlying cytoskeleton is enriched in F-actin and coronin. CHEBI:32370 myristoleate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32370 GO:0055067 monovalent inorganic cation homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055067 Any process involved in the maintenance of an internal steady state of monovalent inorganic cations within an organism or cell. GO:0070682 proteasome regulatory particle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070682 proteasome regulatory complex assembly The aggregation, arrangement and bonding together of a mature, active proteasome regulatory particle complex. GO:0055068 cobalt ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055068 cobalt homeostasis Any process involved in the maintenance of an internal steady state of cobalt ions within an organism or cell. CHEBI:32372 palmitoleate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32372 GO:0070683 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0070683 CHEBI:46992 4-amino-4-deoxy-alpha-L-arabinopyranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46992 CHEBI:46993 4-amino-4-deoxy-beta-L-arabinopyranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46993 CHEBI:46994 D-arabinopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46994 CHEBI:46995 alpha-D-arabinopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46995 CHEBI:46996 beta-D-arabinopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46996 CHEBI:46997 L-ribose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46997 CHEBI:46998 ribofuranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46998 GO:0080036 regulation of cytokinin-activated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080036 regulation of cytokinin mediated signalling|regulation of cytokinin mediated signaling pathway Any process that modulates the frequency, rate or extent of cytokinin signaling. GO:0080037 negative regulation of cytokinin-activated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080037 negative regulation of cytokinin mediated signalling|negative regulation of cytokinin mediated signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of cytokinin signaling. GO:0080038 positive regulation of cytokinin-activated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080038 positive regulation of cytokinin mediated signalling|positive regulation of cytokinin mediated signaling pathway Any process that activates or increases the frequency, rate or extent of cytokinin signaling. GO:0080039 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0080039 GO:0080032 methyl jasmonate esterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080032 MetaCyc:RXN-10767 jasmonic acid methyl ester esterase activity|methyl JA esterase activity|MEJA esterase activity Catalysis of the reaction: a methyl jasmonate + H2O = a jasmonic acid + methanol. GO:0080033 response to nitrite biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080033 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrite stimulus. GO:0080034 host response to induction by symbiont of tumor, nodule or growth in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080034 Any process that results in a change in the state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the formation of an abnormal mass of cells in the host organism, induced by a symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:46990 4-amino-4-deoxy-L-arabinose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46990 GO:0080035 2-hydroxy-but-3-enyl glucosinolate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080035 2-hydroxy-but-3-enyl glucosinolate biosynthesis|progoitrin biosynthesis|progoitrin biosynthetic process|progoitrin synthesis|2-hydroxy-but-3-enyl glucosinolate anabolism|2-hydroxy-but-3-enyl glucosinolate synthesis|2-hydroxy-but-3-enyl glucosinolate formation The chemical reactions and pathways resulting in the formation of progoitrin, a 2-hydroxy-but-3-enyl glucosinolate. Glucosinolates are substituted thioglucosides found in rapeseed products and related cruciferae, and progoitrin has been implicated in causing goiters in mammals and bitter taste in cruciferous vegetables. CHEBI:46991 4-amino-4-deoxy-L-arabinopyranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46991 GO:0055072 iron ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055072 iron homeostasis Any process involved in the maintenance of an internal steady state of iron ions within an organism or cell. CHEBI:32340 dTDP-beta-L-daunosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32340 GO:0055073 cadmium ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055073 cadmium homeostasis Any process involved in the maintenance of an internal steady state of cadmium ions within an organism or cell. GO:0055074 calcium ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055074 regulation of calcium ion concentration Any process involved in the maintenance of an internal steady state of calcium ions within an organism or cell. GO:0080030 methyl indole-3-acetate esterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080030 MetaCyc:RXN-10711|EC:3.1.1.1 Methyl IAA esterase activity|methyl indole-3-acetate esterase activity|indole-3-Acetic acid methyl ester esterase activity|MeIAA esterase activity Catalysis of the reaction: methyl indole-3-acetate + H2O = indole-3-acetate + methanol + H+. GO:0055075 potassium ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055075 Any process involved in the maintenance of an internal steady state of potassium ions within an organism or cell. GO:0080031 methyl salicylate esterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080031 MetaCyc:RXNQT-4366 methylsalicylate esterase activity|MESA esterase activity|salicylic acid methyl ester esterase activity|methyl SA esterase activity Catalysis of the reaction: methyl salicylate + H2O = salicylic acid + methanol + H+. GO:0055070 copper ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055070 copper homeostasis Any process involved in the maintenance of an internal steady state of copper ions within an organism or cell. GO:0055071 manganese ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055071 manganese homeostasis Any process involved in the maintenance of an internal steady state of manganese ions within an organism or cell. GO:0055076 transition metal ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055076 Any process involved in the maintenance of an internal steady state of transition metal ions within an organism or cell. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver. UBERON:0003135 male reproductive organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003135 male reproductive system organ|reproductive organ of male organism|reproductive structure of male organism|male organism reproductive structure|male organism reproductive system organ|male organism reproductive organ|sex organ of male organism|male sex organ|male reproductive gland/organ|male organism sex organ|reproductive system organ of male organism A male organ involved in reproduction GO:0055077 gap junction hemi-channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0055077 connexon channel activity A wide pore channel activity that enables the transport of a solute across a membrane via a gap junction hemi-channel. Two gap junction hemi-channels coupled together form a complete gap junction. GO:0055078 sodium ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055078 Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell. UBERON:0003133 reproductive organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003133 reproductive system organ|genitalia|sex organ|genital organ An organ involved in reproduction UBERON:0003134 female reproductive organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003134 female reproductive system organ|reproductive organ of female organism|reproductive structure of female organism|female organism reproductive system organ|female organism reproductive structure|female organism reproductive organ|sex organ of female organism|female reproductive gland/organ|female sex organ|female organism sex organ|reproductive system organ of female organism A female organ involved in reproduction GO:0055079 aluminum ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055079 aluminium ion homeostasis Any process involved in the maintenance of an internal steady state of aluminum ions within an organism or cell. CHEBI:46981 N-acetylsphingosine 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46981 GO:0080029 cellular response to boron-containing substance levels biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080029 cellular response to boron levels Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of boron-containing substances. CHEBI:46987 alpha-L-arabinopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46987 UBERON:0003119 pharyngeal arch artery 2 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003119 AA2|2nd aortic arch artery|2nd pharyngeal arch artery|2nd branchial arch artery|hyoid aortic arch|second aortic arch|aortic arch 2|2nd arch artery|second branchial arch artery The vessels formed within the second pair of branchial arches in embryogenesis CHEBI:46988 4-amino-4-deoxyarabinose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46988 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080025 PtdIns(3,5)P2 binding Interacting selectively and non-covalently with phosphatidylinositol-3,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' and 5' positions. GO:0080026 response to indolebutyric acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080026 response to indolebutyric acid stimulus|response to indole-3-butyric acid stimulus|response to IBA stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indolebutyric acid stimulus. GO:0080027 response to herbivore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080027 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a herbivore. GO:0080028 nitrile biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080028 The chemical reactions and pathways resulting in the formation of a nitrile, an organic compound containing trivalent nitrogen attached to one carbon atom. GO:0080021 response to benzoic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080021 response to benzoic acid stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzoic acid stimulus. GO:0080022 primary root development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080022 The process whose specific outcome is the progression of the primary root over time, from its formation to the mature structure. The primary root develops directly from the embryonic radicle. GO:0080023 3R-hydroxyacyl-CoA dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080023 Reactome:R-HSA-5676637 Catalysis of the reaction: 3R-hydroxyacyl-CoA = 2E-enoyl-CoA + H2O. GO:0080024 indolebutyric acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080024 IBA metabolic process|IBA metabolism|indole-3-butyric acid metabolic process The chemical reactions and pathways involving indolebutyric acid, a compound that serves as an active or storage form of the hormone indole-3-acetic acid (an auxin) in many plants. UBERON:0003120 pharyngeal arch artery 3 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003120 aortic arch 3|3rd arch artery|3rd aortic arch artery|third aortic arch|AA3|3rd pharyngeal arch artery|third branchial arch artery|3rd branchial arch artery|carotid arch The vessels formed within the third pair of branchial arches in embryogenesis GO:0055083 monovalent inorganic anion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055083 Any process involved in the maintenance of an internal steady state of monovalent inorganic anions within an organism or cell. UBERON:0003121 pharyngeal arch artery 4 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003121 aortic arch 4|fourth branchial arch artery|4th arch artery|AA4|4th aortic arch artery|4th pharyngeal arch artery|systemic arch|4th branchial arch artery|fourth aortic arch The vessels formed within the fourth pair of branchial arches in embryogenesis GO:0055084 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0055084 GO:0055085 transmembrane transport biolink:BiologicalProcess go-plus goslim_generic|goslim_pombe|goslim_chembl|goslim_yeast http://purl.obolibrary.org/obo/GO_0055085 membrane transport|ATP hydrolysis coupled transmembrane transport The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. GO:0080020 regulation of coenzyme A biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080020 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving coenzyme A. GO:0055086 nucleobase-containing small molecule metabolic process biolink:BiologicalProcess go-plus goslim_pombe|goslim_yeast|goslim_drosophila http://purl.obolibrary.org/obo/GO_0055086 nucleobase, nucleoside and nucleotide metabolic process|nucleobase, nucleoside and nucleotide metabolism The cellular chemical reactions and pathways involving a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide. GO:0055080 cation homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055080 Any process involved in the maintenance of an internal steady state of cations within an organism or cell. CHEBI:32356 2,3-dihydroxy-trans-cinnamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32356 CHEBI:32357 trans-3-coumaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32357 GO:0055081 anion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055081 Any process involved in the maintenance of an internal steady state of anions within an organism or cell. GO:0055082 cellular chemical homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055082 Any biological process involved in the maintenance of an internal steady state of a chemical at the level of the cell. CHEBI:46989 pentosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46989 UBERON:0003128 cranium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003128 calvarium|upper part of skull|skeletal system of head|set of bones of cranium|skull minus mandible|bones of cranium|epicranial plate|ossa cranii Upper portion of the skull that excludes the mandible (when present in the organism). UBERON:0003129 skull biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003129 skeletal system of head|cranial skeleton Anatomical structure that is part of the head consisting entirely of cranium and mandible[WP]. UBERON:0003126 trachea biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003126 cartilaginous trachea|tracheal tubule|windpipe|vertebrate trachea The trachea is the portion of the airway that attaches to the bronchi as it branches [GO:dph]. GO:0055087 Ski complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0055087 Wikipedia:Ski_complex A protein complex that regulates RNA degradation by the exosome complex. In Saccharomyces the complex has a heterotetrameric stoichiometry consisting of one copy each of Ski2p and Ski3 and two copies of Ski8p. UBERON:0003124 chorion membrane biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003124 fetal chorion|chorion|embryonic chorion|uterine chorion|chorion frondosum|chorion (vertebrates)|chorionic sac the outermost extraembryonic membrane GO:0055088 lipid homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055088 Any process involved in the maintenance of an internal steady state of lipid within an organism or cell. UBERON:0003125 vitelline membrane biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003125 zona pellucida - vitelline membrane|m. vitellina|zona pellucida|yolk sac membrane A structure directly adjacent to the outer surface of the plasma membrane of an ovum. It is composed mostly of protein fibers, with protein receptors needed for sperm binding, binding to sperm plasma membrane receptors. The species-specificity between these receptors contributes to prevention of breeding between different species [Wikipedia]. A protective layer around the egg[FBbt]. UBERON:0003122 pharyngeal arch artery 5 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003122 aortic arch 5|AA5|fifth aortic arch The vessels formed within the fifth pair of pharyngeal arches in embryogenesis. GO:0055089 fatty acid homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055089 Any process involved in the maintenance of an internal steady state of fatty acid within an organism or cell. UBERON:0003123 pharyngeal arch artery 6 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003123 aortic arch 6|sixth aortic arch|6th arch artery|sixth branchial arch artery|AA6|6th aortic arch artery|pulmonary arch|6th pharyngeal arch artery|6th branchial arch artery The vessels formed within the sixth pair of branchial arches in embryogenesis UBERON:0017750 proximal mesopodial endochondral element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0017750 A mesopodial endochondral element that is in the most proximal part of the mesopodial skeleton, connected to the zeugopodial skeleton. CHEBI:46970 phytosphingosine 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46970 UBERON:0017751 proximal mesopodial cartilage element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0017751 A proximal mesopodial endochondral element that is composed primarily of cartilage tissue. CHEBI:46971 premnaspirodiene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46971 OBA:0001001 macromolecular stability biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0001001 CHEBI:46976 1,4-thiazine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46976 UBERON:0003108 suspensorium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003108 suspensoria|mandibular suspensorium|hyopalatine (1) the arrangement of bones which supports the jaw from the braincase; (2) in teleost fish, a large, usually triangular, bone which supports the jaw. The teleost suspensorium is formed by fusion of various elements which vary among different taxa. GO:0080058 protein deglutathionylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080058 protein amino acid deglutathionylation The protein modification process in which a glutathione molecule is removed from a protein amino acid by breaking a disulfide linkage. FAO:0000050 conidiophore stalk biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/FAO_0000050 The elongated part of the conidiophore that extends, often aerially, from the growth substrate and supports the structures that bear conidia. GO:0080059 flavonol 3-O-arabinosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080059 Catalysis of the reaction: UDP-arabinose + a flavonol = UDP + a flavonol 3-O-D-arabinoside. FAO:0000052 sporangium biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/FAO_0000052 A structure within which spores develop. CHEBI:32328 3-(cis-5,6-dihydroxycyclohexa-1,3-dienyl)acrylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32328 GO:0080054 low-affinity nitrate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080054 low affinity nitrate transmembrane transporter activity Enables the transfer of nitrate ions (NO3-) from one side of a membrane to the other. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations. GO:0080055 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0080055 GO:0080056 petal vascular tissue pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080056 Vascular tissue pattern formation as it occurs in the petal of vascular plants. GO:0080057 sepal vascular tissue pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080057 Vascular tissue pattern formation as it occurs in the sepal of vascular plants. GO:0080050 regulation of seed development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080050 Any process that modulates the frequency, rate or extent of seed development. GO:0055094 response to lipoprotein particle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055094 response to lipoprotein particle stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus. GO:0055095 lipoprotein particle mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055095 lipoprotein particle mediated signal transduction|lipoprotein particle-mediated signaling|lipoprotein mediated signalling A series of molecular signals mediated by the detection of a lipoprotein particle. GO:0080051 cutin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080051 The directed movement of cutin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Cutin, which consists of C16-18 fatty acids, is the major component of the cuticle that covers the plant surface. UBERON:0003110 otic region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003110 cranial vault GO:0055096 low-density lipoprotein particle mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055096 low-density lipoprotein particle mediated signal transduction|low-density lipoprotein particle-mediated signaling|low-density lipoprotein mediated signalling A series of molecular signals mediated by the detection of low-density lipoprotein particle. GO:0080052 response to histidine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080052 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histidine stimulus. GO:0080053 response to phenylalanine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080053 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylalanine stimulus. GO:0055097 high density lipoprotein particle mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055097 high density lipoprotein particle mediated signal transduction|high density lipoprotein particle-mediated signaling|high density lipoprotein mediated signalling A series of molecular signals mediated by the detection of high density lipoprotein particle. GO:0055090 acylglycerol homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055090 glyceride homeostasis Any process involved in the maintenance of an internal steady state of acylglycerol within an organism or cell. GO:0055091 phospholipid homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055091 Any process involved in the maintenance of an internal steady state of phospholipid within an organism or cell. GO:0055092 sterol homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055092 Any process involved in the maintenance of an internal steady state of sterol within an organism or cell. GO:0055093 response to hyperoxia biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055093 response to hyperoxic stress|response to increased oxygen tension Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension. CHEBI:32325 beta-ionone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32325 UBERON:0003117 pharyngeal arch 6 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003117 6th pharyngeal arch|branchial arch 4|visceral arch 6|sixth branchial arch|6th arch|sixth visceral arch|gill arch 4|fourth branchial arch|6th visceral arch|sixth pharyngeal arch The 6th pharyngeal arch. contributes to the development of the sternocleidomastoid and trapezius muscles CHEBI:46978 thiazinemonocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46978 UBERON:0003118 pharyngeal arch artery 1 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003118 first branchial arch artery|1st branchial arch artery|AA1|1st aortic arch artery|1st arch artery|1st pharyngeal arch artery|first arch artery|aortic arch 1|first aortic arch|mandibular aortic arch The vessels formed within the first pair of branchial arches in embryogenesis CHEBI:46979 N-acetylsphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46979 UBERON:0003115 pharyngeal arch 4 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003115 branchial arch 2|fourth visceral arch|visceral arch 4|second branchial arch|4th arch|fourth pharyngeal arch|second gill arch|gill arch 2|4th visceral arch|4th branchial arch|4th pharyngeal arch contributes to development of the cartilage of the larynx, laryngeal, pharyngeal, and soft palate muscles, superior parathyroid gland, and C-cells of the thymus UBERON:0003116 pharyngeal arch 5 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003116 5th pharyngeal arch|branchial arch 3|fifth visceral arch|visceral arch 5|gill arch 3|fifth pharyngeal arch|5th visceral arch|third branchial arch GO:0055098 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0055098 UBERON:0003113 dermatocranium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003113 dendrocranium|dermal skull bones|exocranium|roof of skull|dermal part of skull|roofing bones of the skull|skull exoskeleton|dermal bone cranium|skull roof|dermal skull roof|dermatocranial cover Subdivision of skeleton that includes all dermal bones in the cranial skeleton[ZFA,modified]. UBERON:0003114 pharyngeal arch 3 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003114 3rd pharyngeal arch|branchial arch 1|first branchial arch|visceral arch 3|3rd arch|gill arch 1|first gill arch|third visceral arch|3rd visceral arch|third pharyngeal arch The third branchial arch contributes to the development of the hyoid bone, stylopharyngeus muscle, inferior parathyroid gland, and thymus. GO:0055099 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0055099 UBERON:0003111 sphenoid region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003111 Anatomical cluster that forms the floor and sidewalls of the middle part of the cranium. UBERON:0003112 olfactory region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003112 ethmoid region Anatomical cluster that is located in the anterior region of the cranium and provides structural support for the olfactory organ. CHEBI:46960 dTMP(-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46960 CHEBI:46961 phytosphingosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46961 CHEBI:46963 2-aminooctadecene-1,3-diol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46963 CHEBI:46964 2-aminooctadec-4-ene-1,3-diol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46964 CHEBI:46965 (2R,3S)-2-aminooctadec-4-ene-1,3-diol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46965 CHEBI:46966 2-amino-1-hydroxyoctadecan-3-one biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46966 GO:0080047 GDP-L-galactose phosphorylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080047 EC:2.7.7.69|RHEA:27698|MetaCyc:RXNQT-4141 Catalysis of the reaction: GDP-L-galactose + phosphate = L-galactose-1-P + GDP. GO:0080048 GDP-D-glucose phosphorylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080048 EC:2.7.7.78|MetaCyc:RXN-12486|RHEA:30387 Catalysis of the reaction: GDP-D-glucose + phosphate = D-glucose-1-P + GDP. GO:0080049 L-gulono-1,4-lactone dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080049 MetaCyc:RXN-1439 Catalysis of the reaction: L-gulono-1,4-lactone + 2 ferricytochrome c = L-ascorbate + 2 ferrocytochrome c. GO:0080043 quercetin 3-O-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080043 Catalysis of the transfer of a glucosyl group from UDP-glucose to the 3-hydroxy group of a quercetin molecule. GO:0080044 quercetin 7-O-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080044 Catalysis of the transfer of a glucosyl group from UDP-glucose to the 7-hydroxy group of a quercetin molecule. GO:0080045 quercetin 3'-O-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080045 Catalysis of the transfer of a glucosyl group from UDP-glucose to the 3'-hydroxy group of a quercetin molecule. GO:0080046 quercetin 4'-O-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080046 MetaCyc:RXN-10788 Catalysis of the transfer of a glucosyl group from UDP-glucose to the 4'-hydroxy group of a quercetin molecule. GO:0080040 positive regulation of cellular response to phosphate starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080040 Any process that activates or increases the frequency, rate or extent of cellular response to phosphate starvation. GO:0080041 ADP-ribose pyrophosphohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080041 Catalysis of the reaction: ADP-ribose + H2O = AMP + ribose-1-phosphate. GO:0080042 ADP-glucose pyrophosphohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080042 Catalysis of the reaction: ADP-glucose + H2O = AMP + glucose-1-phosphate. CHEBI:32333 dTDP-5,5-di-C-methyl-beta-L-lyxose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32333 CHEBI:32336 dTDP-beta-L-vancosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32336 CHEBI:46967 L-erythro-sphingosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46967 CHEBI:46968 2-aminooctadecane-1,3-diol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46968 UBERON:0003104 mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyma|mesenchymal tissue|mesenchyme tissue|portion of mesenchymal tissue|portion of mesenchyme tissue Portion of tissue composed of mesenchymal cells (motile cells that develop from epthelia via an epithelial to mesenchymal transition) and surrounding extracellular material. Mesenchyme has different embryological origins in different metazoan taxa - in many invertebrates it derives in whole or part from ectoderm. In vertebrates it derives largely from mesoderm, and sometimes the terms are used interchangeably, e.g. lateral plate mesoderm/mesenchyme. CHEBI:46969 benzoxazine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46969 UBERON:0003102 surface structure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003102 surface region|surface feature|surface structures|anatomical surface feature Anatomical structure that overlaps the outer epithelial layer and is adjacent to the space surrounding the organism. UBERON:0003103 compound organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003103 organ Anatomical structure that has as its parts two or more multi-tissue structures of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona fide boundaries from other distinct anatomical structures of different types. UBERON:0003100 female organism biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003100 female human body|female Gonochoristic organism that can produce female gametes. UBERON:0003101 male organism biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003101 male human body|male Gonochoristic organism that can produce male gametes. GO:0031229 intrinsic component of nuclear inner membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031229 intrinsic to nuclear inner membrane The component of the nuclear inner membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0031227 intrinsic component of endoplasmic reticulum membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031227 intrinsic to endoplasmic reticulum membrane The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0031228 intrinsic component of Golgi membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031228 intrinsic to Golgi membrane The component of the Golgi membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0006269 DNA replication, synthesis of RNA primer biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006269 replication priming The synthesis of a short RNA polymer, usually 4-15 nucleotides long, using one strand of unwound DNA as a template; the RNA then serves as a primer from which DNA polymerases extend synthesis. GO:0031225 anchored component of membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031225 anchored to membrane The component of a membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. GO:0031226 intrinsic component of plasma membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031226 intrinsic to plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0045875 negative regulation of sister chromatid cohesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045875 down regulation of sister chromatid cohesion|downregulation of sister chromatid cohesion|down-regulation of sister chromatid cohesion|inhibition of sister chromatid cohesion Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid cohesion. GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006267 pre-replicative complex formation|pre-replicative complex assembly|nuclear pre-replicative complex assembly|pre-RC complex assembly The aggregation, arrangement and bonding together of a set of components to form the nuclear pre-replicative complex, a protein-DNA complex that forms at the eukaryotic DNA replication origin and is required for replication initiation. GO:0045876 positive regulation of sister chromatid cohesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045876 upregulation of sister chromatid cohesion|up regulation of sister chromatid cohesion|activation of sister chromatid cohesion|stimulation of sister chromatid cohesion|up-regulation of sister chromatid cohesion Any process that activates or increases the frequency, rate or extent of sister chromatid cohesion. GO:0006268 DNA unwinding involved in DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006268 DNA unwinding during replication|DNA unwinding factor The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating unpaired template strands for DNA replication. GO:0006265 DNA topological change biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006265 DNA underwinding The process in which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number. GO:0045873 negative regulation of sevenless signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045873 down-regulation of sevenless signaling pathway|negative regulation of sev signaling pathway|inhibition of sevenless signaling pathway|negative regulation of sevenless signalling pathway|down regulation of sevenless signaling pathway|downregulation of sevenless signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the sevenless signaling pathway. GO:0045874 positive regulation of sevenless signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045874 up regulation of sevenless signaling pathway|activation of sevenless signaling pathway|stimulation of sevenless signaling pathway|positive regulation of sev signaling pathway|up-regulation of sevenless signaling pathway|upregulation of sevenless signaling pathway|positive regulation of sevenless signalling pathway Any process that activates or increases the frequency, rate or extent of the sevenless signaling pathway. GO:0006266 DNA ligation biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0006266 The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase. GO:0045871 obsolete negative regulation of rhodopsin gene expression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045871 negative regulation of rhodopsin gene activity|downregulation of rhodopsin gene activity|down-regulation of rhodopsin gene activity|inhibition of rhodopsin gene activity|down regulation of rhodopsin gene activity OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of rhodopsin gene expression. GO:0006263 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006263 GO:0006264 mitochondrial DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006264 mtDNA synthesis|mtDNA replication|mitochondrial DNA synthesis|replication of mitochondrial DNA The process in which new strands of DNA are synthesized in the mitochondrion. GO:0045872 obsolete positive regulation of rhodopsin gene expression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045872 up regulation of rhodopsin gene activity|activation of rhodopsin gene activity|stimulation of rhodopsin gene activity|up-regulation of rhodopsin gene activity|upregulation of rhodopsin gene activity|positive regulation of rhodopsin gene activity OBSOLETE. Any process that activates or increases the frequency, rate or extent of rhodopsin gene expression. GO:0006261 DNA-dependent DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006261 A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands. CHEBI:81276 allodeoxycholic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_81276 GO:0045870 positive regulation of single stranded viral RNA replication via double stranded DNA intermediate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045870 up-regulation of retroviral genome replication|upregulation of retroviral genome replication|up regulation of retroviral genome replication|activation of retroviral genome replication|positive regulation of retroviral genome replication|stimulation of retroviral genome replication Any process that activates or increases the frequency, rate or extent of retroviral genome replication. GO:0006262 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006262 GO:0070839 metal ion export biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070839 divalent metal ion export The directed movement of metal cations, out of a cell or organelle. GO:0006270 DNA replication initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006270 DNA re-replication initiation|DNA endoreduplication initiation|DNA-dependent DNA replication initiation The process in which DNA-dependent DNA replication is started; this begins with the ATP dependent loading of an initiator complex onto the DNA, this is followed by DNA melting and helicase activity. In bacteria, the gene products that enable the helicase activity are loaded after the initial melting and in archaea and eukaryotes, the gene products that enable the helicase activity are inactive when they are loaded and subsequently activate. GO:0006271 DNA strand elongation involved in DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006271 DNA replication elongation|DNA strand elongation during DNA replication The process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand, complementary to an existing template, as part of DNA replication. GO:0070837 dehydroascorbic acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070837 dehydroascorbate transport The directed movement of dehydroascorbate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dehydroascorbate, 5-(1,2-dihydroxyethyl)furan-2,3,4(5H)-trione, is an oxidized form of vitamin C. GO:0070838 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0070838 GO:0045879 negative regulation of smoothened signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045879 negative regulation of smoothened activity|negative regulation of smoothened signalling pathway|negative regulation of hedgehog signaling pathway|negative regulation of smoothened receptor activity by patched|negative regulation of smoothened by patched|downregulation of smoothened signaling pathway|down regulation of smoothened signaling pathway|inhibition of smoothened signaling pathway|negative regulation of hh signaling pathway|down-regulation of smoothened signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling. GO:0070835 chromium ion transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070835 Enables the transfer of chromium (Cr) ions from one side of a membrane to the other. GO:0070836 caveola assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070836 caveolar biogenesis|caveola formation The aggregation, arrangement and bonding together of a set of components to form a caveola. A caveola is a plasma membrane raft that forms a small pit, depression, or invagination that communicates with the outside of a cell and extends inward, indenting the cytoplasm and the cell membrane. GO:0070833 phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via CDP-N-methylethanolamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070833 MetaCyc:PWY4FS-3 The phosphatidylcholine biosynthetic process that begins with an initial N-methylation with phospho-base phosphoethanolamine, followed by two downstream N-methylations on phosphatidyl-bases, phosphatidyl-N-methylethanolamine and phosphatidyl-N-dimethylethanolamine. The process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine. GO:0045877 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045877 GO:0045878 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045878 GO:0070834 phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-N-dimethylethanolamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070834 MetaCyc:PWY4FS-4 The phosphatidylcholine biosynthetic process that begins with two N-methylations with phospho-base phosphoethanolamine and phospho-N-methylethanolamine, followed by a downstream N-methylation on phosphatidyl-base phosphatidyl-N-dimethylethanolamine; the process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine. GO:0070831 basement membrane assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070831 The aggregation, arrangement and bonding together of a set of components to form a basement membrane, a part of the extracellular region that consists of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. GO:0031223 auditory behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031223 behavioural response to sound|behavioral response to sound|auditory behaviour The behavior of an organism in response to a sound. GO:0070832 phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-choline biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070832 MetaCyc:PWY4FS-2 The phosphatidylcholine biosynthetic process that begins with three consecutive N-methylation steps that are carried out on phospho-bases, phosphoethanolamine, phospho-N-methylethanolamine, and phospho-N-dimethylethanolamine; the process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine. GO:0031224 intrinsic component of membrane biolink:CellularComponent go-plus goslim_metagenomics http://purl.obolibrary.org/obo/GO_0031224 intrinsic to membrane The component of a membrane consisting of the gene products having some covalently attached portion, for example part of a peptide sequence or some other covalently attached group such as a GPI anchor, which spans or is embedded in one or both leaflets of the membrane. GO:0031221 arabinan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031221 arabinan metabolism The chemical reactions and pathways involving arabinan, a polysaccharide composed of arabinose residues. GO:0070830 bicellular tight junction assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070830 tight junction formation The aggregation, arrangement and bonding together of a set of components to form a tight junction, an occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet. GO:0031222 arabinan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031222 arabinan catabolism|arabinan degradation|arabinan breakdown The chemical reactions and pathways resulting in the breakdown of arabinan, a polysaccharide composed of arabinose residues. GO:0031220 maltodextrin phosphorylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031220 MetaCyc:RXN-9025|MetaCyc:RXN0-5182|RHEA:29691 Catalysis of the reaction: maltodextrin = glucose-1-phosphate. GO:0021890 olfactory bulb interneuron fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021890 The process in which the developmental fate of a neuroblast becomes restricted such that it will develop into an interneuron residing in the olfactory bulb. GO:0031218 arabinogalactan endo-1,4-beta-galactosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031218 MetaCyc:3.2.1.89-RXN|EC:3.2.1.89 galactanase activity|arabinogalactan 4-beta-D-galactanohydrolase activity|arabinogalactanase activity|endo-1,4-beta-galactanase activity Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in arabinogalactans. GO:0021891 olfactory bulb interneuron development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021891 The process whose specific outcome is the progression of an interneuron residing in the olfactory bulb, from its initial commitment, to the fully functional differentiated cell. GO:0021892 cerebral cortex GABAergic interneuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021892 The process in which a relatively unspecialized cell acquires specialized features of a GABAergic interneuron residing in the cerebral cortex. GO:0031219 levanase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031219 MetaCyc:3.2.1.65-RXN|EC:3.2.1.65 levan hydrolase activity|2,6-beta-D-fructan fructanohydrolase activity Catalysis of the random hydrolysis of 2,6-beta-D-fructofuranosidic linkages in 2,6-beta-D-fructans (levans) containing more than 3 fructose units. GO:0031216 neopullulanase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031216 MetaCyc:3.2.1.135-RXN|EC:3.2.1.135 pullulanase II activity|pullulan 4-D-glucanohydrolase (panose-forming) Catalysis of the hydrolysis of pullulan to panose (6-alpha-D-glucosylmaltose). GO:0021893 cerebral cortex GABAergic interneuron fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021893 The process in which the developmental fate of a neuroblast becomes restricted such that it will develop into a GABAergic interneuron residing in the cerebral cortex. GO:0021894 cerebral cortex GABAergic interneuron development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021894 The process whose specific outcome is the progression of a cerebral cortex GABAergic interneuron over time, from initial commitment to its fate, to the fully functional differentiated cell. GO:0031217 glucan 1,4-beta-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031217 MetaCyc:3.2.1.74-RXN|EC:3.2.1.74 exo-1,4-beta-glucosidase activity|beta-1,4-glucanase activity|beta-1,4-beta-glucanase activity|1,4-beta-D-glucan glucohydrolase activity|exo-beta-1,4-glucanase activity|exo-1,4-beta-glucanase activity|exocellulase activity|exo-1,4-beta-D-glucosidase activity|exo-beta-1,4-glucosidase activity Catalysis of the hydrolysis of (1->4) linkages in (1->4)-beta-D-glucans, to remove successive glucose units. GO:0021895 cerebral cortex neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021895 The process in which a relatively unspecialized cell acquires specialized features of a neuron residing in the cerebral cortex. GO:0031214 biomineral tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031214 Wikipedia:Biomineralization Formation of hard tissues that consist mainly of inorganic compounds, and also contain a small amounts of organic matrices that are believed to play important roles in their formation. GO:0021896 forebrain astrocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021896 The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte residing in the forebrain. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function. GO:0031215 shell calcification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031215 The precipitation of calcium carbonate onto the organic matrix of a shell, such as a mollusc shell. GO:0045886 negative regulation of synaptic growth at neuromuscular junction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045886 downregulation of synaptic growth at neuromuscular junction|down-regulation of synaptic growth at neuromuscular junction|inhibition of synaptic growth at neuromuscular junction|down regulation of synaptic growth at neuromuscular junction Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic growth at neuromuscular junction. GO:0006278 RNA-dependent DNA biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006278 A DNA biosynthetic process that uses RNA as a template for RNA-dependent DNA polymerases (e.g. reverse transcriptase) that synthesize the new strand. GO:0006279 premeiotic DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006279 DNA replication involved in S phase involved in meiotic cell cycle|meiotic cell cycle DNA replication|DNA replication during S phase involved in meiotic cell cycle|nuclear cell cycle DNA replication involved in meiotic cell cycle|meiotic nuclear cell cycle DNA replication|meiotic DNA synthesis|premeiotic DNA synthesis|meiotic DNA replication|DNA replication involved in S-phase involved in meiotic cell cycle The replication of DNA that precedes meiotic cell division. GO:0045887 positive regulation of synaptic growth at neuromuscular junction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045887 up regulation of synaptic growth at neuromuscular junction|activation of synaptic growth at neuromuscular junction|stimulation of synaptic growth at neuromuscular junction|up-regulation of synaptic growth at neuromuscular junction|upregulation of synaptic growth at neuromuscular junction Any process that activates or increases the frequency, rate or extent of synaptic growth at neuromuscular junction. GO:0045884 obsolete regulation of survival gene product expression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045884 regulation of survival gene product activity|regulation of survival gene products|regulation of survival gene product expression OBSOLETE. Any process that modulates the frequency, rate or extent of survival gene product expression; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level. GO:0006276 plasmid maintenance biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0006276 The maintenance of the integrity of extrachromosomal plasmid DNA; includes processes that ensure plasmids are retained in the daughter cells after cell division. GO:0045885 obsolete positive regulation of survival gene product expression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045885 positive regulation of survival gene product activity|up-regulation of survival gene product activity|activation of survival gene product activity|positive regulation of survival gene products|up regulation of survival gene product activity|stimulation of survival gene product activity|upregulation of survival gene product activity|positive regulation of survival gene product expression OBSOLETE. Any process that activates or increases the frequency, rate or extent of survival gene product expression; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level. GO:0006277 DNA amplification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006277 The process in which the number of copies of a gene is increased in certain cells as extra copies of DNA are made in response to certain signals of cell development or of stress from the environment. GO:0045882 negative regulation of sulfur utilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045882 down-regulation of sulfur utilization|downregulation of sulfur utilization|down regulation of sulfur utilization|inhibition of sulfur utilization|negative regulation of sulphur utilization Any process that stops, prevents, or reduces the frequency, rate or extent of sulfur utilization. GO:0006274 DNA replication termination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006274 The process in which DNA replication at a replication fork ceases; occurs when the replication fork reaches a specific termination site or when two replication forks meet. GO:0045883 positive regulation of sulfur utilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045883 stimulation of sulfur utilization|up-regulation of sulfur utilization|activation of sulfur utilization|up regulation of sulfur utilization|upregulation of sulfur utilization|positive regulation of sulphur utilization Any process that activates or increases the frequency, rate or extent of sulfur utilization. GO:0006275 regulation of DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006275 Any process that modulates the frequency, rate or extent of DNA replication. GO:0045880 positive regulation of smoothened signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045880 stimulation of smoothened signaling pathway|up-regulation of smoothened signaling pathway|activation of smoothened signaling pathway|positive regulation of smoothened signalling pathway|positive regulation of smoothened receptor activity by patched|positive regulation of hh signaling pathway|up regulation of smoothened signaling pathway|positive regulation of hedgehog signaling pathway|positive regulation of smoothened by patched|upregulation of smoothened signaling pathway Any process that activates or increases the frequency, rate or extent of smoothened signaling. GO:0070819 menaquinone-dependent protoporphyrinogen oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070819 protoporphyrinogen-IX:menaquinone oxidoreductase activity Catalysis of the reaction: protoporphyrinogen IX + menaquinone = protoporphyrin IX + reduced menaquinone. GO:0006272 leading strand elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006272 The process in which an existing DNA strand is extended continuously in a 5' to 3' direction by activities including the addition of nucleotides to the 3' end of the strand, complementary to an existing template, as part of DNA replication. Leading strand elongation proceeds in the same direction as the replication fork. GO:0045881 positive regulation of sporulation resulting in formation of a cellular spore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045881 stimulation of sporulation|up-regulation of sporulation|upregulation of sporulation|up regulation of sporulation|activation of sporulation Any process that activates or increases the frequency, rate or extent of sporulation. GO:0006273 lagging strand elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006273 The process in which an existing DNA strand is extended in a net 3' to 5' direction by activities including the addition of nucleotides to the 3' end of the strand, complementary to an existing template, as part of DNA replication. Lagging strand DNA elongation proceeds by discontinuous synthesis of short stretches of DNA, known as Okazaki fragments, from RNA primers; these fragments are then joined by DNA ligase. Although each segment of nascent DNA is synthesized in the 5' to 3' direction, the overall direction of lagging strand synthesis is 3' to 5', mirroring the progress of the replication fork. GO:0006281 DNA repair biolink:BiologicalProcess go-plus goslim_drosophila|goslim_pombe|goslim_yeast|goslim_pir http://purl.obolibrary.org/obo/GO_0006281 Wikipedia:DNA_repair The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway. GO:0070828 heterochromatin organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070828 heterochromatin organisation Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin, a compact and highly condensed form of chromatin. GO:0006282 regulation of DNA repair biolink:BiologicalProcess go-plus goslim_metagenomics http://purl.obolibrary.org/obo/GO_0006282 Any process that modulates the frequency, rate or extent of DNA repair. GO:0070829 heterochromatin maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070829 maintenance of heterochromatic silencing|heterochromatin maintenance involved in chromatin silencing|maintenance of chromatin silencing The chromatin organization process that preserves heterochromatin in a stable functional or structural state. GO:0070826 paraferritin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070826 A cytoplasmic protein complex that contains integrin, mobilferrin and a flavin monooxygenase, is capable of reducing Fe(III) to Fe(II) utilizing NADPH, and is involved in iron transport. Fe(II) is required in the cell as the substrate for ferrochelatase in the synthesis of heme. GO:0070827 chromatin maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070827 The chromatin organization process that preserves chromatin in a stable functional or structural state. GO:0006280 obsolete mutagenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006280 mutagenesis OBSOLETE. The process by which genetic material undergoes a detectable and heritable structural change. There are three categories of mutation: genome mutations, involving addition or subtraction of one or more whole chromosomes; chromosome mutations, which alter the structure of chromosomes; and gene mutations, where the structure of a gene is altered at the molecular level. GO:0070824 SHREC complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070824 A histone deacetylase complex that contains a core of four proteins -- Clr1, Clr2, Clr3, and Mit1 in fission yeast -- and localizes to all heterochromatic regions in the genome as well as some euchromatic sites. The complex is involved in regulating nucleosome positioning to assemble higher-order chromatin structures. GO:0070825 micropyle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070825 An external encapsulating structure part of the chorion. A single cone-shaped specialization that forms an opening in the egg chorion that allows sperm entry into the egg prior to fertilization. GO:0045888 obsolete regulation of transcription of homeotic gene (Polycomb group) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045888 regulation of transcription of homeotic gene (Polycomb group) OBSOLETE. Any process that modulates the frequency, rate or extent of transcription of homeotic genes of the Polycomb group. GO:0070822 Sin3-type complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070822 Any of a number of evolutionarily conserved histone deacetylase complexes (HDACs) containing a core consisting of a paired amphipathic helix motif protein (e.g. Sin3p in S. cerevisiae, Pst1 in S. pombe or Sin3A in mammals) at least one class I histone deacetylase (e.g. Rpd3p in S. cerevisiae, Clr6 in S. pombe, or HDAC1 and HDAC2 in mammals), and at least one WD40 repeat protein (e.g. Ume1p in S. cerevisiae, Prw1 in S. pombe, or RbAp46 and RbAp48 in mammals). These complexes also contain a variable number of other proteins that direct histone binding, DNA binding, or add other functionality to the complex. GO:0045889 obsolete positive regulation of transcription of homeotic gene (Polycomb group) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045889 positive regulation of transcription of homeotic gene (Polycomb group) OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription of homeotic genes of the Polycomb group. GO:0070823 HDA1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070823 A tetrameric histone deacetylase complex that contains a Class II deacetylase catalytic subunit. In S. cerevisiae it is composed of two Hda1p subunits along with Hda2p and Hda3p. GO:0070820 tertiary granule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070820 gelatinase granule A secretory granule that contains cathepsin and gelatinase and is readily exocytosed upon cell activation; found primarily in mature neutrophil cells. GO:0031212 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031212 GO:0021897 forebrain astrocyte development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021897 The process aimed at the progression of an astrocyte that resides in the forebrain, from initial commitment of the cell to its fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function. GO:0031213 RSF complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031213 remodeling and spacing factor complex An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2H in mammals) and an RSF1 homolog. It mediates nucleosome deposition and generates regularly spaced nucleosome arrays. In mammals, RSF is involved in regulation of transcription from RNA polymerase II promoters). GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021898 The initial commitment of cells whereby the developmental fate of a cell becomes restricted such that it will develop into some type of neuron in the forebrain. GO:0070821 tertiary granule membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070821 The lipid bilayer surrounding a tertiary granule. GO:0031210 phosphatidylcholine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031210 Interacting selectively and non-covalently with phosphatidylcholine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of choline. GO:0021899 fibroblast growth factor receptor signaling pathway involved in forebrain neuron fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021899 fibroblast growth factor receptor signalling pathway involved in forebrain neuron fate commitment The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain. GO:0031211 endoplasmic reticulum palmitoyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031211 A complex of the endoplasmic reticulum that catalyzes S-palmitoylation, the addition of palmitate (C16:0) or other long-chain fatty acids to proteins at a cysteine residue. GO:0031209 SCAR complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031209 WRC|WAVE regulatory complex|WAVE complex A pentameric complex that includes orthologues of human PIR121, Nap1, Abi, SCAR, and HSPC300 and regulates actin polymerization and/or depolymerization through small GTPase mediated signal transduction. GO:0045890 obsolete regulation of transcription of homeotic gene (trithorax group) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045890 regulation of transcription of homeotic gene (trithorax group) OBSOLETE. Any process that modulates the frequency, rate or extent of transcription of homeotic genes of the trithorax group. GO:0021880 Notch signaling pathway involved in forebrain neuron fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021880 Notch signalling pathway involved in forebrain neuron fate commitment The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain. GO:0031207 Sec62/Sec63 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031207 Sec62/63 complex|ER protein translocation subcomplex A protein complex involved in the posttranslational targeting of proteins to the ER. In yeast, it is a tetrameric complex consisting of Sec62p, Sec63p, Sec71p and Sec72p. GO:0021881 Wnt-activated signaling pathway involved in forebrain neuron fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021881 Wnt receptor signaling pathway involved in forebrain neuron fate commitment|Wnt receptor signalling pathway involved in forebrain neuron fate commitment|Wnt-activated signaling pathway involved in forebrain neuron fate commitment The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell that contributes to the commitment of a neuroblast to aneuronal fate. The neuron will reside in the forebrain. GO:0031208 POZ domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031208 broad-complex, tramtrack, and bric-a-brac domain binding|BTB domain Interacting selectively and non-covalently with a POZ (poxvirus and zinc finger) domain of a protein, a protein-protein interaction domain found in many transcription factors. GO:0006249 dCMP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006249 dCMP catabolism|dCMP degradation|dCMP breakdown The chemical reactions and pathways resulting in the breakdown of dCMP, deoxycytidine monophosphate. GO:0021882 obsolete regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021882 OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain. GO:0031205 endoplasmic reticulum Sec complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0031205 An endoplasmic reticulum membrane-associated complex involved in the translocation of proteins that are targeted to the ER. In yeast, this complex consists of two subcomplexes, namely, the Sec61 complex and the Sec62/Sec63 complex. GO:0021883 cell cycle arrest of committed forebrain neuronal progenitor cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021883 The process in which the cell cycle is halted during one of the normal phases (G1, S, G2, M) in a cell that has been committed to become a neuron that will reside in the forebrain. GO:0031206 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031206 GO:0006247 obsolete TTP reduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006247 TTP reduction OBSOLETE. (Was not defined before being made obsolete). GO:0021884 forebrain neuron development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021884 The process whose specific outcome is the progression of a neuron that resides in the forebrain, from its initial commitment to its fate, to the fully functional differentiated cell. GO:0031203 posttranslational protein targeting to membrane, docking biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031203 protein docking during posttranslational protein targeting to membrane|posttranslational protein membrane targeting, docking|Sec-translated protein complex assembly The process in which the signal sequence of a translated protein binds to and forms a complex with the Sec complex. GO:0021885 forebrain cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021885 The orderly movement of a cell from one site to another at least one of which is located in the forebrain. GO:0006248 CMP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006248 CMP degradation|CMP catabolism|CMP breakdown The chemical reactions and pathways resulting in the breakdown of CMP, cytidine monophosphate. GO:0031204 posttranslational protein targeting to membrane, translocation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031204 protein translocation during posttranslational protein targeting to membrane|posttranslational protein membrane targeting, translocation The process in which a protein translocates through the ER membrane posttranslationally. GO:0006245 TDP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006245 TDP catabolism|TDP degradation|TDP breakdown The chemical reactions and pathways resulting in the breakdown of TDP, ribosylthymine diphosphate. GO:0045897 obsolete positive regulation of transcription during mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045897 mitotic activation of transcription|up regulation of transcription during mitosis|positive regulation of transcription, mitotic|upregulation of transcription during mitosis|stimulation of transcription during mitosis|activation of transcription during mitosis|up-regulation of transcription during mitosis OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription that occurs during the mitotic cell cycle. GO:0006246 dTDP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006246 dTDP degradation|dTDP breakdown|dTDP catabolism The chemical reactions and pathways resulting in the breakdown of dTDP, deoxyribosylthymine diphosphate. GO:0045898 regulation of RNA polymerase II transcription preinitiation complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly|regulation of RNA polymerase II transcriptional preinitiation complex formation|regulation of RNA polymerase II transcriptional pre-initiation complex biosynthesis|regulation of RNA polymerase II transcriptional pre-initiation complex assembly Any process that modulates the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly. GO:0045895 positive regulation of mating-type specific transcription, DNA-templated biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045895 up-regulation of transcription, mating-type specific|positive regulation of mating-type specific transcription, DNA-dependent|upregulation of transcription, mating-type specific|up regulation of transcription, mating-type specific|activation of transcription, mating-type specific|stimulation of transcription, mating-type specific Any mating-type specific process that activates or increases the rate of cellular DNA-templated transcription. GO:0006243 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006243 GO:0045896 obsolete regulation of transcription during mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045896 regulation of transcription, mitotic|mitotic regulation of transcription OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of transcription that occurs during the mitotic cell cycle. GO:0006244 pyrimidine nucleotide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006244 pyrimidine nucleotide degradation|pyrimidine nucleotide breakdown|pyrimidine nucleotide catabolism The chemical reactions and pathways resulting in the breakdown of a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. GO:0045893 positive regulation of transcription, DNA-templated biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045893 upregulation of transcription, DNA-dependent|stimulation of transcription, DNA-dependent|positive regulation of transcription, DNA-dependent|upregulation of gene-specific transcription|activation of transcription, DNA-dependent|up-regulation of transcription, DNA-dependent|transcription activator activity|stimulation of gene-specific transcription|up regulation of gene-specific transcription|positive regulation of cellular transcription, DNA-dependent|positive regulation of gene-specific transcription|up regulation of transcription, DNA-dependent|activation of gene-specific transcription|up-regulation of gene-specific transcription Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription. GO:0006241 CTP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006241 CTP biosynthesis|CTP anabolism|CTP synthesis|CTP formation The chemical reactions and pathways resulting in the formation of CTP, cytidine 5'-triphosphate. GO:0045894 negative regulation of mating-type specific transcription, DNA-templated biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045894 inhibition of transcription, mating-type specific|negative regulation of mating-type specific transcription, DNA-dependent|down regulation of transcription, mating-type specific|downregulation of transcription, mating-type specific|down-regulation of transcription, mating-type specific Any mating-type specific process that stops, prevents or reduces the rate of cellular DNA-templated transcription. GO:0006242 dCTP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006242 dCTP formation|dCTP anabolism|dCTP biosynthesis|dCTP synthesis The chemical reactions and pathways resulting in the formation of dCTP, deoxycytidine triphosphate. GO:0045891 obsolete negative regulation of transcription of homeotic gene (trithorax group) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045891 negative regulation of transcription of homeotic gene (trithorax group) OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription of homeotic genes of the trithorax group. CHEBI:81298 beta-muricholic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_81298 GO:0045892 negative regulation of transcription, DNA-templated biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045892 negative regulation of transcription, DNA-dependent|inhibition of gene-specific transcription|down regulation of gene-specific transcription|transcription repressor activity|downregulation of gene-specific transcription|down-regulation of transcription, DNA-dependent|negative regulation of cellular transcription, DNA-dependent|negative regulation of gene-specific transcription|down-regulation of gene-specific transcription|downregulation of transcription, DNA-dependent|down regulation of transcription, DNA-dependent|inhibition of transcription, DNA-dependent Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription. GO:0006240 dCDP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006240 dCDP anabolism|dCDP biosynthesis|dCDP synthesis|dCDP formation The chemical reactions and pathways resulting in the formation of dCDP, deoxycytidine 5'-diphosphate. GO:0070859 positive regulation of bile acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070859 upregulation of bile acid biosynthetic process|positive regulation of bile acid anabolism|positive regulation of bile acid synthesis|stimulation of bile acid biosynthetic process|positive regulation of bile acid formation|up-regulation of bile acid biosynthetic process|activation of bile acid biosynthetic process|positive regulation of bile acid biosynthesis|up regulation of bile acid biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids. GO:0070857 regulation of bile acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070857 regulation of bile acid anabolism|regulation of bile acid biosynthesis|regulation of bile acid synthesis|regulation of bile acid formation Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids. GO:0070858 negative regulation of bile acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070858 down regulation of bile acid biosynthetic process|inhibition of bile acid biosynthetic process|negative regulation of bile acid anabolism|negative regulation of bile acid synthesis|negative regulation of bile acid formation|negative regulation of bile acid biosynthesis|down-regulation of bile acid biosynthetic process|downregulation of bile acid biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids. GO:0045899 positive regulation of RNA polymerase II transcription preinitiation complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045899 positive regulation of RNA polymerase II transcriptional pre-initiation complex assembly|up regulation of RNA polymerase II transcriptional preinitiation complex assembly|upregulation of RNA polymerase II transcriptional preinitiation complex assembly|positive regulation of RNA polymerase II transcriptional preinitiation complex formation|stimulation of RNA polymerase II transcriptional preinitiation complex assembly|up-regulation of RNA polymerase II transcriptional preinitiation complex assembly|activation of RNA polymerase II transcriptional preinitiation complex assembly|positive regulation of RNA polymerase II transcriptional pre-initiation complex biosynthesis|positive regulation of RNA polymerase II transcriptional preinitiation complex assembly Any process that activates or increases the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly. GO:0070855 myosin VI head/neck binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070855 Interacting selectively and non-covalently with the head/neck region of a myosin VI heavy chain. GO:0070856 myosin VI light chain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070856 Interacting selectively and non-covalently with a light chain of a myosin VI complex. GO:0021886 hypothalamus gonadotrophin-releasing hormone neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021886 hypothalamus gonadotropin-releasing hormone neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron located in the hypothalamus. These neurons release gonadotrophin-releasing hormone as a neural transmitter. GO:0070853 myosin VI binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070853 Interacting selectively and non-covalently with a class VI myosin. The myosin VI heavy chain has a single IQ motif in the neck and a tail region with a coiled coil domain followed by a unique globular domain, a unique insertion that enables myosin VI to move towards the pointed or minus end of actin filaments. GO:0031201 SNARE complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031201 A protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. One well-characterized example is the neuronal SNARE complex formed of synaptobrevin 2, syntaxin 1a, and SNAP-25. GO:0021887 hypothalamus gonadotrophin-releasing hormone neuron fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021887 hypothalamus gonadotropin-releasing hormone neuron fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a hypothalamus neuron that releases gonadotrophin-releasing hormone. GO:0031202 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031202 GO:0070854 myosin VI heavy chain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070854 Interacting selectively and non-covalently with a heavy chain of a myosin VI complex. GO:0070851 growth factor receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070851 Interacting selectively and non-covalently with a growth factor receptor. GO:0021888 hypothalamus gonadotrophin-releasing hormone neuron development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021888 hypothalamus gonadotropin-releasing hormone neuron development The process whose specific outcome is the progression of a hypothalamus gonadotrophin-releasing hormone neuron over time, from initial commitment of its fate, to the fully functional differentiated cell. GO:0070852 cell body fiber biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070852 primary neurite|cell body fibre A neuron projection that is found in unipolar neurons and corresponds to the region between the cell body and the point at which the single projection branches. GO:0021889 olfactory bulb interneuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021889 The process in which a neuroblast acquires specialized features of an interneuron residing in the olfactory bulb. GO:0031200 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031200 GO:0070850 TACC/TOG complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070850 A protein complex that contains the transforming acidic coiled coil (TACC) protein and the TOG protein (Mia1p/Alp7p and Alp14, respectively, in fission yeast), and is involved in microtubule array remodeling as cells progress through the cell cycle. The TACC/TOG complex is conserved in eukaryotes, associates with microtubules, and shuttles between the nucleus and the cytoplasm during interphase. GO:0021870 Cajal-Retzius cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021870 The process in which a neuroblast acquires specialized structural and/or functional features of a Cajal-Retzius cell, one of a transient population of pioneering neurons in the cerebral cortex. These cells are slender bipolar cells of the developing marginal zone. One feature of these cells in mammals is that they express the Reelin gene. GO:0021871 forebrain regionalization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021871 The regionalization process resulting in the creation of areas within the forebrain that will direct the behavior of cell migration in differentiation as the forebrain develops. GO:0021872 forebrain generation of neurons biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021872 generation of neurons in forebrain The process in which nerve cells are generated in the forebrain. This includes the production of neuroblasts from and their differentiation into neurons. GO:0006258 UDP-glucose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006258 UDP-glucose conversion|UDP-glucose catabolism|UDP-glucose degradation|UDP-glucose breakdown The chemical reactions and pathways resulting in the breakdown of UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate. GO:0021873 forebrain neuroblast division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021873 The division of a neuroblast located in the forebrain. Neuroblast division gives rise to at least another neuroblast. GO:0006259 DNA metabolic process biolink:BiologicalProcess go-plus goslim_generic|goslim_flybase_ribbon|goslim_chembl|goslim_agr|goslim_candida|goslim_plant|goslim_pir|goslim_aspergillus|goslim_metagenomics http://purl.obolibrary.org/obo/GO_0006259 DNA metabolism|cellular DNA metabolism Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides. GO:0021874 Wnt signaling pathway involved in forebrain neuroblast division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021874 Wnt receptor signaling pathway involved in forebrain neuroblast division|Wnt receptor signalling pathway in forebrain neuroblast division|Wnt-activated signaling pathway involved in forebrain neuroblast division The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell that contributes to the self renewal of neuroblasts in the forebrain. GO:0006256 UDP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006256 UDP catabolism|UDP degradation|UDP breakdown The chemical reactions and pathways resulting in the breakdown of UDP, uridine (5'-)diphosphate. GO:0006257 dUDP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006257 dUDP breakdown|dUDP catabolism|dUDP degradation The chemical reactions and pathways resulting in the breakdown of dUDP, deoxyuridine (5'-)diphosphate. GO:0006254 CTP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006254 CTP catabolism|CTP degradation|CTP hydrolysis|CTP breakdown The chemical reactions and pathways resulting in the breakdown of CTP, cytidine 5'-triphosphate. GO:0006255 obsolete UDP reduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006255 UDP reduction OBSOLETE. (Was not defined before being made obsolete). GO:0006252 obsolete CTP reduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006252 CTP reduction OBSOLETE. (Was not defined before being made obsolete). GO:0006253 dCTP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006253 dCTP breakdown|dCTP catabolism|dCTP degradation The chemical reactions and pathways resulting in the breakdown of dCTP, deoxycytidine triphosphate. GO:0006250 obsolete CDP reduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006250 CDP reduction OBSOLETE. (Was not defined before being made obsolete). GO:0006251 dCDP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006251 dCDP degradation|dCDP breakdown|dCDP catabolism The chemical reactions and pathways resulting in the breakdown of dCDP, deoxycytidine 5'-diphosphate. GO:0006260 DNA replication biolink:BiologicalProcess go-plus goslim_pir|goslim_drosophila|goslim_pombe|goslim_yeast http://purl.obolibrary.org/obo/GO_0006260 Wikipedia:DNA_replication The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA. GO:0070848 response to growth factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070848 response to growth factor stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus. GO:0070849 response to epidermal growth factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070849 response to epidermal growth factor stimulus|response to EGF stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus. GO:0070846 Hsp90 deacetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070846 The modification of an Hsp90 protein by removal of acetyl groups. GO:0070847 core mediator complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070847 S mediator complex|C mediator complex A protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The core mediator complex has a stimulatory effect on basal transcription, and contains most of the same subdomains as the larger form of mediator complex -- a head domain comprising proteins known in Saccharomyces as Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; and a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p -- but lacks the regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan core mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins. GO:0070844 polyubiquitinated protein transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070844 polyubiquitylated protein transport The directed movement of polyubiquitinated proteins in a cell, including the movement of proteins between specific compartments or structures within a cell. GO:0070845 polyubiquitinated misfolded protein transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070845 polyubiquitylated misfolded protein transport|misfolded polyubiquitinated protein transport The directed movement of misfolded polyubiquitinated proteins in a cell, including the movement of proteins between specific compartments or structures within a cell. GO:0070842 aggresome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070842 The aggregation, arrangement and bonding together of a set of components to form an aggresome; requires the microtubule cytoskeleton and dynein. GO:0021875 fibroblast growth factor receptor signaling pathway involved in forebrain neuroblast division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021875 fibroblast growth factor receptor signalling pathway in forebrain neuroblast division The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to the self renewal of neuroblasts in the forebrain. GO:0070843 misfolded protein transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070843 The directed movement of misfolded proteins in a cell, including the movement of proteins between specific compartments or structures within a cell. GO:0021876 Notch signaling pathway involved in forebrain neuroblast division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021876 Notch signalling pathway in forebrain neuroblast division The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the self renewal of neuroblasts in the forebrain. GO:0070840 dynein complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070840 dynein binding Interacting selectively and non-covalently with a dynein complex, a protein complex that contains two or three dynein heavy chains and several light chains, and has microtubule motor activity. GO:0021877 forebrain neuron fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021877 The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron that resides in the forebrain. GO:0070841 inclusion body assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070841 The aggregation, arrangement and bonding together of a set of components to form an inclusion body. GO:0021878 forebrain astrocyte fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021878 The process in which the developmental fate of a cell becomes restricted such that it will develop into an astrocyte that resides in the forebrain. GO:0021879 forebrain neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021879 The process in which a relatively unspecialized cell acquires specialized features of a neuron that will reside in the forebrain. GO:0006229 dUTP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006229 dUTP anabolism|dUTP synthesis|dUTP biosynthesis|dUTP formation The chemical reactions and pathways resulting in the formation of dUTP, deoxyuridine (5'-)triphosphate. GO:0006227 dUDP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006227 dUDP synthesis|dUDP biosynthesis|dUDP formation|dUDP anabolism The chemical reactions and pathways resulting in the formation of dUDP, deoxyuridine diphosphate (2'-deoxy-5'-uridylyl phosphate). GO:0021860 pyramidal neuron development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021860 projection neuron development The progression of a pyramidal neuron from its initial formation to its mature state. GO:0021861 forebrain radial glial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021861 radial glial cell differentiation in forebrain The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the forebrain. Differentiation includes the processes involved in commitment of a cell to a specific fate. GO:0006228 UTP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006228 UTP anabolism|UTP synthesis|UTP formation|UTP biosynthesis The chemical reactions and pathways resulting in the formation of UTP, uridine (5'-)triphosphate. GO:0006225 UDP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006225 UDP formation|UDP biosynthesis|UDP anabolism|UDP synthesis The chemical reactions and pathways resulting in the formation of UDP, uridine (5'-)diphosphate. GO:0021862 early neuron differentiation in forebrain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021862 The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of neurons. Differentiation includes the processes involved in commitment of a cell to a specific fate. GO:0021863 forebrain neuroblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021863 non-surface dividing progenitor cell differentiation|abventricular progenitor cell differentiation|intermediate progenitor cell differentiation The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of basal progenitor cells, neuroblasts that lose their contacts with the ventricular surface. Differentiation includes the processes involved in commitment of a cell to a specific fate. GO:0006226 dUMP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006226 dUMP anabolism|dUMP synthesis|dUMP formation|dUMP biosynthesis The chemical reactions and pathways resulting in the formation of dUMP, deoxyuridine monophosphate (2'-deoxyuridine 5'-phosphate). GO:0006223 uracil salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006223 Any process that generates uracil, 2,4-dioxopyrimidine, from derivatives of it without de novo synthesis. GO:0006224 obsolete uridine kinase reaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006224 uridine kinase reaction OBSOLETE. (Was not defined before being made obsolete). GO:0006221 pyrimidine nucleotide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006221 pyrimidine nucleotide anabolism|pyrimidine nucleotide synthesis|pyrimidine nucleotide formation|pyrimidine nucleotide biosynthesis The chemical reactions and pathways resulting in the formation of a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. GO:0006222 UMP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006222 UMP anabolism|UMP synthesis|UMP formation|UMP biosynthesis The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate. GO:0006220 pyrimidine nucleotide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006220 pyrimidine nucleotide metabolism|pyrimidine metabolic process|pyrimidine metabolism The chemical reactions and pathways involving a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. GO:0070879 fungal-type cell wall beta-glucan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070879 fungal-type cell wall beta-glucan metabolism The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells. GO:0070877 microprocessor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070877 IntAct:EBI-9519056|IntAct:EBI-9519039 A protein complex that binds to heme and to pri-miRNAs, and is required for the formation of a pre-microRNA (pre-miRNA), the initial step of microRNA (miRNA) biogenesis. The complex is composed of the double-stranded-RNA-specific RNase Drosha (also called RNASEN) and the RNA-binding protein DGCR8 (heme-free or heme-bound forms). Within the complex, DGCR8 function as a molecular anchor necessary for the recognition of pri-miRNA at dsRNA-ssRNA junction and directs RNASEN/Drosha to cleave the 3' and 5' strands of a stem-loop to release hairpin-shaped pre-miRNAs. GO:0070878 primary miRNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070878 pri-miRNA binding|primary microRNA binding Interacting selectively and non-covalently with a primary microRNA (pri-miRNA) transcript, an RNA molecule that is processed into a short hairpin-shaped structure called a pre-miRNA and finally into a functional miRNA. Both double-stranded and single-stranded regions of a pri-miRNA are required for binding. GO:0021864 obsolete radial glial cell division in forebrain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021864 OBSOLETE. The mitotic division of radial glial cells in the developing forebrain. GO:0070875 positive regulation of glycogen metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070875 positive regulation of glycogen metabolism Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glycogen. GO:0070876 SOSS complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070876 A protein complex that functions downstream of the MRN complex to promote DNA repair and the G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and is composed of SOSS-B (SOSS-B1/OBFC2B or SOSS-B2/OBFC2A), SOSS-A/INTS3 and SOSS-C/C9orf80. GO:0021865 obsolete symmetric radial glial cell division in forebrain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021865 OBSOLETE. The mitotic division of a radial glial cell giving rise to two new radial glial cells in the forebrain. GO:0021866 obsolete asymmetric radial glial cell division in forebrain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021866 OBSOLETE. The mitotic cell division of a radial glial cell giving rise to a radial glial cell and another cell type. GO:0070873 regulation of glycogen metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070873 regulation of glycogen metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glycogen. GO:0070874 negative regulation of glycogen metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070874 negative regulation of glycogen metabolism Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glycogen. GO:0021867 obsolete neuron-producing asymmetric radial glial cell division in forebrain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021867 OBSOLETE. The unequal mitotic division of a radial glial cell in the forebrain that gives rise to a radial glial cell and a post-mitotic neuronal progenitor. GO:0070871 cell wall organization involved in conjugation with cellular fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070871 cell wall organisation involved in conjugation with cellular fusion A process of cell wall organization that contributes to conjugation with cellular fusion. GO:0021868 obsolete ventricular zone cell-producing asymmetric radial glial cell division in forebrain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021868 OBSOLETE. The unequal mitotic division of a forebrain radial glial cell that gives rise to a radial glial cell and a ventricular zone cell. GO:0070872 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0070872 GO:0021869 forebrain ventricular zone progenitor cell division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021869 The mitotic division of a basal progenitor giving rise to two neurons. GO:0070870 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0070870 GO:0006238 CMP salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006238 cytidine monophosphate salvage Any process that generates CMP, cytidine monophosphate, from derivatives of it without de novo synthesis. GO:0006239 dCMP salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006239 deoxycytidine monophosphate salvage Any process that generates dCMP, deoxycytidine monophosphate from derivatives of it, without de novo synthesis. GO:0021850 subpallium glioblast cell division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021850 glioblast cell division in subpallium|glioblast division in ventral telencephalon The division of glioblasts in the subpallium. These cells will give rise to oligodendrocytes. GO:0021851 neuroblast division in dorsal lateral ganglionic eminence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021851 The division of neuroblasts in the dorsal region of the lateral ganglionic eminence. These cells give rise to embryonic interneuron precursors that will migrate tangentially to the olfactory bulb. GO:0006236 cytidine salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006236 Any process that generates cytidine, cytosine riboside, from derivatives of it without de novo synthesis. GO:0021852 pyramidal neuron migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021852 projection neuron migration The migration of pyramidal a neuron precursor from the ventricular zone to the correct layer of the cerebral cortex. GO:0006237 deoxycytidine salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006237 Any process that generates deoxycytidine, 2-deoxyribosylcytosine, from derivatives of it, without de novo synthesis. GO:0006234 TTP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006234 TTP formation|TTP biosynthesis|TTP anabolism|TTP synthesis The chemical reactions and pathways resulting in the formation of TTP, ribosylthymine triphosphate. GO:0006235 dTTP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006235 dTTP synthesis|dTTP biosynthesis|dTTP formation|dTTP anabolism The chemical reactions and pathways resulting in the formation of dTTP, deoxyribosylthymine triphosphate. GO:0006232 TDP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006232 TDP anabolism|TDP synthesis|TDP formation|TDP biosynthesis The chemical reactions and pathways resulting in the formation of TDP, ribosylthymine diphosphate. GO:0006233 dTDP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006233 dTDP anabolism|dTDP synthesis|dTDP biosynthesis|dTDP formation The chemical reactions and pathways resulting in the formation of dTDP, deoxyribosylthymine diphosphate (2'-deoxyribosylthymine5'-diphosphate). GO:0006230 TMP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006230 TMP biosynthesis|TMP anabolism|TMP synthesis|TMP formation The chemical reactions and pathways resulting in the formation of TMP, ribosylthymine monophosphate. GO:0006231 dTMP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006231 dTMP biosynthesis|dTMP anabolism|dTMP synthesis|dTMP formation The chemical reactions and pathways resulting in the formation of dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate). GO:0070868 heterochromatin organization involved in chromatin silencing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070868 heterochromatin organisation involved in chromatin silencing Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin and contributes to chromatin silencing. GO:0070869 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0070869 GO:0070866 sterol-dependent protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070866 Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) in the presence of sterols. GO:0070867 mating projection tip membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070867 mating projection membrane fusion domain|shmoo tip membrane The portion of the plasma membrane surrounding a mating projection tip. GO:0070864 sperm individualization complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070864 A macromolecular complex that includes cytoskeletal components and part of the cell membrane. Forms at the nuclear end of a male germline syncytium, or cyst, and translocates the over the length of the syncytium in the course of sperm individualization. Each complex contains an array of 64 investment cones, one per nucleus, that move synchronously along the spermatogenic cyst. GO:0021853 cerebral cortex GABAergic interneuron migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021853 The migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex. GO:0070865 investment cone biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070865 F-actin cone A cytoskeletal part that consists of a microfilament-rich cone that forms round each nucleus in a spermatogenic cyst and translocates the length of the cyst during sperm individualization. GO:0021854 hypothalamus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021854 The progression of the hypothalamus region of the forebrain, from its initial formation to its mature state. GO:0070862 negative regulation of protein exit from endoplasmic reticulum biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070862 down regulation of protein exit from endoplasmic reticulum|negative regulation of protein export from endoplasmic reticulum|downregulation of protein exit from endoplasmic reticulum|down-regulation of protein exit from endoplasmic reticulum|negative regulation of protein exit from ER|inhibition of protein exit from endoplasmic reticulum|negative regulation of protein export from ER Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the endoplasmic reticulum. GO:0021855 hypothalamus cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021855 The directed movement of a cell into the hypothalamus region of the forebrain. GO:0070863 positive regulation of protein exit from endoplasmic reticulum biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070863 positive regulation of protein export from ER|positive regulation of protein export from endoplasmic reticulum|up regulation of protein exit from endoplasmic reticulum|activation of protein exit from endoplasmic reticulum|stimulation of protein exit from endoplasmic reticulum|up-regulation of protein exit from endoplasmic reticulum|positive regulation of protein exit from ER|upregulation of protein exit from endoplasmic reticulum Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the endoplasmic reticulum. GO:0021856 hypothalamic tangential migration using cell-axon interactions biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021856 The movement of a hypothalamic neuronal precursor tangentially through the forebrain using an interaction of the migrating cells with axons of other neurons. GO:0070860 RNA polymerase I core factor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070860 A RNA polymerase I-specific transcription factor complex that is required for the transcription of rDNA by RNA polymerase I. In yeast the complex consists of Rrn6p, Rrn7p, and Rrn11p. GO:0021857 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0021857 GO:0070861 regulation of protein exit from endoplasmic reticulum biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070861 regulation of protein export from ER|regulation of protein export from endoplasmic reticulum|regulation of protein exit from ER Any process that modulates the frequency, rate or extent of the directed movement of proteins from the endoplasmic reticulum. GO:0021858 GABAergic neuron differentiation in basal ganglia biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021858 The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic inhibitory neuron in the basal ganglia. Differentiation includes the processes involved in commitment of a neuroblast to a GABAergic neuron. GO:0021859 pyramidal neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021859 projection neuron differentiation The process in which a neuroblast or one of its progeny commits to a pyramidal neuron fate, migrates from the ventricular zone to the appropriate layer in the cortex and develops into a mature neuron. GO:0006209 cytosine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006209 cytosine catabolism|cytosine degradation|cytosine breakdown The chemical reactions and pathways resulting in the breakdown of cytosine, 4-amino-2-hydroxypyrimidine, a pyrimidine derivative that is one of the five main bases found in nucleic acids; it occurs widely in cytidine derivatives. GO:0070890 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0070890 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006207 'de novo' pyrimidine base anabolism|'de novo' pyrimidine base synthesis|'de novo' pyrimidine base formation|'de novo' pyrimidine base biosynthesis|'de novo' pyrimidine base biosynthetic process The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases, beginning with the synthesis of a pyrimidine ring from simpler precursors. GO:0006208 pyrimidine nucleobase catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006208 pyrimidine base catabolism|pyrimidine base catabolic process|pyrimidine base degradation|pyrimidine base breakdown The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases. GO:0006205 obsolete pyrimidine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006205 pyrimidine metabolic process OBSOLETE. (Was not defined before being made obsolete). GO:0006206 pyrimidine nucleobase metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006206 pyrimidine metabolic process|pyrimidine base metabolism|pyrimidine metabolism|pyrimidine base metabolic process The chemical reactions and pathways involving pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases. GO:0006203 dGTP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006203 dGTP catabolism|dGTP degradation|dGTP breakdown The chemical reactions and pathways resulting in the breakdown of dGTP, guanosine triphosphate. GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021840 The creation and reception of signals that control the direction of migration of interneurons as a component of the process of migration from the subpallium to the cortex. GO:0021841 chemoattraction involved in interneuron migration from the subpallium to the cortex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021841 positive chemotaxis involved in interneuron migration from the subpallium to the cortex The creation and reception of signals that result in the movement of interneurons toward the signal, where this process is involved in migration from the subpallium to the cortex. GO:0006204 IMP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006204 IMP degradation|IMP breakdown|IMP catabolism The chemical reactions and pathways resulting in the breakdown of IMP, inosine monophosphate. GO:0006201 GMP catabolic process to IMP biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006201 GMP breakdown to IMP|GMP degradation to IMP The chemical reactions and pathways resulting in the breakdown of guanosine monophosphate into other compounds, including inosine monophosphate. GO:0006202 GMP catabolic process to guanine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006202 GMP breakdown to guanine|GMP degradation to guanine The chemical reactions and pathways resulting in the breakdown of guanosine monophosphate into other compounds, including guanine. GO:0006200 obsolete ATP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006200 Wikipedia:ATP_hydrolysis ATP catabolism|ATP hydrolysis|ATP degradation|ATP breakdown OBSOLETE. The chemical reactions and pathways resulting in the breakdown of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0070899 mitochondrial tRNA wobble uridine modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070899 The process in which a uridine in position 34 of a mitochondrial tRNA is post-transcriptionally modified. GO:0021842 chemorepulsion involved in interneuron migration from the subpallium to the cortex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021842 negative chemotaxis involved in interneuron migration from the subpallium to the cortex The creation and reception of signals that result in the movement of interneurons away from the signal during migration from the subpallium to the cortex. GO:0070897 transcription preinitiation complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070897 transcriptional preinitiation complex formation|DNA-templated transcriptional preinitiation complex assembly|transcription PIC biosynthesis|DNA-dependent transcriptional preinitiation complex assembly|transcription PIC formation The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcriptional preinitiation complex (PIC), required for transcription. GO:0070898 RNA polymerase III preinitiation complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070898 RNA polymerase III hybrid type promoter transcriptional preinitiation complex assembly|RNA polymerase III transcription PIC formation|RNA polymerase III transcriptional preinitiation complex assembly|RNA polymerase III type 3 promoter transcriptional preinitiation complex assembly|RNA polymerase III type 2 promoter transcriptional preinitiation complex assembly|RNA polymerase III type 1 promoter transcriptional preinitiation complex assembly|RNA polymerase III transcription PIC biosynthesis|RNA polymerase III transcriptional preinitiation complex formation The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription from an RNA polymerase III promoter. GO:0021843 substrate-independent telencephalic tangential interneuron migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021843 The directional movement of tangentially migrating interneurons that are not guided by attaching to extracellular substrates. GO:0021844 interneuron sorting involved in substrate-independent cerebral cortex tangential migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021844 The establishment and response to guidance cues that distribute interneurons to different cerebral cortex structures. GO:0070895 negative regulation of transposon integration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070895 downregulation of transposon integration|down regulation of transposon integration|inhibition of transposon integration|down-regulation of transposon integration Any process that stops, prevents, or reduces the frequency, rate or extent of transposon integration, a process in which a transposable element is incorporated into another DNA molecule. GO:0070896 positive regulation of transposon integration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070896 up regulation of transposon integration|upregulation of transposon integration|stimulation of transposon integration|up-regulation of transposon integration|activation of transposon integration Any process that activates or increases the frequency, rate or extent of transposon integration, a process in which a transposable element is incorporated into another DNA molecule. GO:0021845 neurotransmitter-mediated guidance of interneurons involved in substrate-independent cerebral cortex tangential migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021845 The response of migrating interneurons to neurotransmitters that alter electrical activity in cells in calcium dependent manner. GO:0021846 cell proliferation in forebrain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021846 The creation of greater cell numbers in the forebrain due to cell division of progenitor cells. GO:0070893 transposon integration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070893 Any process in which a transposable element is incorporated into another DNA molecule such as a chromosome. GO:0021847 ventricular zone neuroblast division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021847 neuroblast division in ventricular zone The proliferation of neuroblasts in the ventricular zone of the cerebral cortex. The neuronal progenitors of these cells will migrate radially. GO:0070894 regulation of transposon integration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070894 Any process that modulates the frequency, rate or extent of regulation of transposon integration, a process in which a transposable element is incorporated into another DNA molecule. GO:0021848 neuroblast division in subpallium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021848 neuroblast division in the ventral telencephalon The division of neuroblasts in the subpallium area of the forebrain. The interneuron precursors that these cells give rise to include GABAergic interneurons and will migrate tangentially. GO:0070891 lipoteichoic acid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070891 Interacting selectively and non-covalently with lipoteichoic acid. GO:0021849 neuroblast division in subventricular zone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021849 The division of neuroblasts in the subventricular zone of the forebrain. The interneuron precursors that these cells give rise to include adult olfactory bulb interneurons and migrate tangentially. GO:0070892 lipoteichoic acid immune receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070892 lipoteichoic acid receptor activity Combining with lipoteichoic acid and transmitting the signal to initiate an innate immune response. GO:0006218 uridine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006218 uridine catabolism|uridine degradation|uridine breakdown The chemical reactions and pathways resulting in the breakdown of uridine, uracil riboside, a ribonucleoside very widely distributed but occurring almost entirely as phosphoric esters in ribonucleotides and ribonucleic acids. GO:0006219 deoxyuridine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006219 deoxyuridine degradation|deoxyuridine breakdown|deoxyuridine catabolism The chemical reactions and pathways resulting in the breakdown of deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA. GO:0006216 cytidine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006216 cytidine degradation|cytidine breakdown|cytidine catabolism The chemical reactions and pathways resulting in the breakdown of cytidine, cytosine riboside, a widely distributed nucleoside. GO:0006217 deoxycytidine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006217 deoxycytidine degradation|deoxycytidine catabolism|deoxycytidine breakdown The chemical reactions and pathways resulting in the breakdown of deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA. GO:0006214 thymidine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006214 thymidine degradation|deoxyribosylthymine catabolic process|thymidine breakdown|thymidine catabolism|deoxyribosylthymine catabolism The chemical reactions and pathways resulting in the breakdown of thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA. GO:0006215 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006215 GO:0021830 interneuron migration from the subpallium to the cortex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021830 The directed movement of interneurons from the subpallium to the cortex during forebrain development. GO:0006212 uracil catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006212 uracil breakdown|uracil catabolism|uracil degradation The chemical reactions and pathways resulting in the breakdown of uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA. GO:0006213 pyrimidine nucleoside metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006213 pyrimidine nucleoside metabolism|pyrimidine metabolic process|pyrimidine metabolism The chemical reactions and pathways involving any pyrimidine nucleoside, one of a family of organic molecules consisting of a pyrimidine base covalently bonded to ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside). GO:0006210 thymine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006210 thymine degradation|thymine breakdown|thymine catabolism The chemical reactions and pathways resulting in the breakdown of thymine, 5-methyluracil, one of the two major pyrimidine bases present (as thymidine) in DNA but not found in RNA other than (as ribothymidine) in transfer RNA, where it is a minor base. GO:0006211 5-methylcytosine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006211 5-methylcytosine degradation|5-methylcytosine catabolism|5-methylcytosine breakdown The chemical reactions and pathways resulting in the breakdown of 5-methylcytosine, a methylated base of DNA. GO:0021839 interneuron-substratum interaction involved in interneuron migration from the subpallium to the cortex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021839 The process in which migrating interneurons interact with an external substratum as a component of migration from the subpallium to the cortex. GO:0070888 E-box binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070888 E-box promoter binding Interacting selectively and non-covalently with an E-box, a DNA motif with the consensus sequence CANNTG that is found in the promoters of a wide array of genes expressed in neurons, muscle and other tissues. GO:0070889 platelet alpha granule organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070889 platelet alpha granule organization and biogenesis|platelet alpha-granule organization|platelet alpha granule organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a platelet alpha granule. A platelet alpha granule is a secretory organelle found in blood platelets. GO:0070886 positive regulation of calcineurin-NFAT signaling cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070886 upregulation of calcineurin-NFAT signaling cascade|stimulation of calcineurin-NFAT signaling cascade|up-regulation of calcineurin-NFAT signaling cascade|positive regulation of NFAT protein import into nucleus|activation of calcineurin-NFAT signaling cascade|positive regulation of calcineurin-NFAT signaling pathway|up regulation of calcineurin-NFAT signaling cascade|positive regulation of calcineurin-NFAT signalling cascade Any process that activates or increases the frequency, rate or extent of signaling via the calcineurin-NFAT signaling cascade. GO:0021831 embryonic olfactory bulb interneuron precursor migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021831 The directed movement of individual interneuron precursors during the embryonic development of the olfactory bulb. GO:0070887 cellular response to chemical stimulus biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0070887 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus. GO:0021832 cell-cell adhesion involved in cerebral cortex tangential migration using cell-cell interactions biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021832 The attachment of cells to one another to form groups of cells involved in cerebral cortex tangential migration. GO:0070884 regulation of calcineurin-NFAT signaling cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070884 NFAT protein import into nucleus|regulation of NFAT protein import into nucleus|regulation of calcineurin-NFAT signalling cascade|regulation of calcineurin-NFAT signaling pathway Any process that modulates the frequency, rate or extent of the calcineurin-NFAT signaling cascade. GO:0021833 cell-matrix adhesion involved in tangential migration using cell-cell interactions biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021833 The interaction of a cell and the extracellular matrix involved in the directed tangential movement of cells mediated by cell-cell interactions in the developing cerebral cortex. GO:0070885 negative regulation of calcineurin-NFAT signaling cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070885 down regulation of calcineurin-NFAT signaling cascade|negative regulation of calcineurin-NFAT signalling cascade|inhibition of calcineurin-NFAT signaling cascade|negative regulation of NFAT protein import into nucleus|termination of calcineurin-NFAT signaling cascade|negative regulation of calcineurin-NFAT signaling pathway|down-regulation of calcineurin-NFAT signaling cascade|inhibition of NFAT protein import into nucleus|downregulation of calcineurin-NFAT signaling cascade Any process that stops, prevents, or reduces the frequency, rate or extent of the calcineurin-NFAT signaling cascade. GO:0021834 chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021834 negative chemotaxis involved in embryonic olfactory bulb interneuron precursor migration The creation and reception of signals that guide olfactory bulb interneuron precursors down concentration gradients towards the olfactory bulb. GO:0021835 chemoattraction involved in embryonic olfactory bulb interneuron precursor migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021835 positive chemotaxis involved in embryonic olfactory bulb interneuron precursor migration The creation and reception of signals that result in the migration of interneuron precursors up a concentration gradient towards the olfactory bulb. GO:0070882 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0070882 GO:0070883 pre-miRNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070883 pre-microRNA binding|precursor microRNA binding Interacting selectively and non-covalently with a precursor microRNA (pre-miRNA) transcript, a stem-loop-containing precursor of microRNA. GO:0021836 chemorepulsion involved in postnatal olfactory bulb interneuron migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021836 negative chemotaxis involved in postnatal olfactory bulb interneuron migration The creation and reception of signals that repel olfactory bulb interneurons from the subventricular zone as a component process in tangential migration. GO:0070880 fungal-type cell wall beta-glucan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070880 fungal-type cell wall beta-glucan biosynthesis|fungal-type cell wall beta-glucan anabolism|fungal-type cell wall beta-glucan synthesis|fungal-type cell wall beta-glucan formation The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells. GO:0021837 motogenic signaling involved in postnatal olfactory bulb interneuron migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021837 motogenic signalling involved in postnatal olfactory bulb interneuron migration The signaling that results in the stimulation of cell movement in the rostral migratory stream. GO:0070881 regulation of proline transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070881 Any process that modulates the frequency, rate or extent of proline transport. GO:0021838 motogenic signaling involved in interneuron migration from the subpallium to the cortex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021838 motogenic signalling involved in interneuron migration from the subpallium to the cortex The creation and reception of signals that result in the directional movement of interneuron precursors from the subpallium to the cortex. CHEBI:71875 9-ribosyl-trans-zeatin 5'-diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71875 CHEBI:22909 borate ion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22909 CHEBI:22907 bleomycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22907 CHEBI:22908 borate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22908 CHEBI:22901 bisphenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22901 CHEBI:22902 bisphosphoglyceric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22902 CHEBI:22905 blasticidin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22905 CHEBI:81200 (S)-corytuberine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_81200 GO:0045806 negative regulation of endocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045806 inhibition of endocytosis|down regulation of endocytosis|downregulation of endocytosis|down-regulation of endocytosis Any process that stops, prevents, or reduces the frequency, rate or extent of endocytosis. GO:0031292 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031292 GO:0045807 positive regulation of endocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045807 up-regulation of endocytosis|upregulation of endocytosis|up regulation of endocytosis|activation of endocytosis|stimulation of endocytosis Any process that activates or increases the frequency, rate or extent of endocytosis. GO:0031293 membrane protein intracellular domain proteolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031293 membrane protein solubilization The proteolytic cleavage of a transmembrane protein leading to the release of an intracellular domain. GO:0045804 negative regulation of eclosion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045804 downregulation of eclosion|down regulation of eclosion|inhibition of eclosion|down-regulation of eclosion Any process that stops, prevents, or reduces the frequency, rate or extent of eclosion. GO:0031290 retinal ganglion cell axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031290 retinal ganglion cell axon pathfinding The process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues. CHEBI:22918 branched-chain amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22918 GO:0031291 Ran protein signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031291 A series of molecular signals within the cell that are mediated by a member of the Ran family of proteins switching to a GTP-bound active state. GO:0045805 positive regulation of eclosion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045805 up regulation of eclosion|upregulation of eclosion|stimulation of eclosion|up-regulation of eclosion|activation of eclosion Any process that activates or increases the frequency, rate or extent of eclosion. GO:0045802 obsolete negative regulation of cytoskeleton biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045802 negative regulation of cytoskeleton OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the organization, biogenesis or maintenance of the cytoskeleton. GO:0045803 obsolete positive regulation of cytoskeleton biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045803 positive regulation of cytoskeleton OBSOLETE. Any process that activates or increases the frequency, rate or extent of the organization, biogenesis or maintenance of the cytoskeleton. GO:0045800 negative regulation of chitin-based cuticle tanning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045800 down-regulation of cuticle tanning|negative regulation of cuticle tanning|negative regulation of cuticle hardening|inhibition of cuticle tanning|down regulation of cuticle tanning|downregulation of cuticle tanning Any process that stops, prevents, or reduces the frequency, rate or extent of chitin-based cuticular tanning. GO:0045801 positive regulation of chitin-based cuticle tanning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045801 activation of cuticle tanning|positive regulation of cuticle tanning|positive regulation of cuticle hardening|stimulation of cuticle tanning|up-regulation of cuticle tanning|upregulation of cuticle tanning|up regulation of cuticle tanning Any process that activates or increases the frequency, rate or extent of chitin-based cuticular tanning. CHEBI:22912 bornane monoterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22912 GO:0031298 replication fork protection complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031298 replisome progression complex|Swi1-Swi3 complex|TIMELESS-TIPIN complex A protein complex conserved in eukaryotes and associated with the replication fork; the complex stabilizes stalled replication forks and is thought to be involved in coordinating leading- and lagging-strand synthesis and in replication checkpoint signaling. GO:0031299 taurine-pyruvate aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031299 MetaCyc:TAURINE-AMINOTRANSFERASE-RXN|EC:2.6.1.77|RHEA:10420|KEGG_REACTION:R05652 taurine:pyruvate aminotransferase activity|Tpa Catalysis of the reaction: pyruvate + taurine = L-alanine + sulfoacetaldehyde. GO:0031296 B cell costimulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031296 B-cell costimulation|B cell co-stimulation|B-lymphocyte costimulation|B-lymphocyte co-stimulation|B-cell co-stimulation|B lymphocyte costimulation|B lymphocyte co-stimulation The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the B cell receptor to augment B cell activation. CHEBI:22916 boron molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22916 CHEBI:22917 phytogenic insecticide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22917 GO:0031297 replication fork processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031297 recovery from replication fork arrest at rDNA locus|replication fork restart|recovery from replication fork stalling at rDNA locus|collapsed replication fork processing|replication fork processing at rDNA locus|replication fork processing at ribosomal DNA locus|recovery from replication fork arrest|replication restart|recovery from replication fork stalling The process in which a DNA replication fork that has stalled is restored to a functional state and replication is restarted. The stalling may be due to DNA damage, DNA secondary structure, bound proteins, dNTP shortage, or other causes. GO:0031294 lymphocyte costimulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031294 lymphocyte co-stimulation The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the B- or T cell receptor to augment B- or T cell activation. GO:0045808 negative regulation of establishment of competence for transformation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045808 inhibitor of the establishment of competence for transformation activity|downregulation of establishment of competence for transformation|down regulation of establishment of competence for transformation|inhibition of establishment of competence for transformation|down-regulation of establishment of competence for transformation Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of competence for transformation. GO:0031295 T cell costimulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031295 T lymphocyte costimulation|T cell co-stimulation|T-cell costimulation|T-lymphocyte costimulation|T-cell co-stimulation The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment T cell activation. GO:0045809 positive regulation of establishment of competence for transformation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045809 up regulation of establishment of competence for transformation|activator of the establishment of competence for transformation activity|upregulation of establishment of competence for transformation|stimulation of establishment of competence for transformation|up-regulation of establishment of competence for transformation|activation of establishment of competence for transformation Any process that activates or increases the frequency, rate or extent of establishment of competence for transformation. GO:0045810 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045810 GO:0031281 positive regulation of cyclase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031281 upregulation of cyclase activity|stimulation of cyclase activity|up-regulation of cyclase activity|activation of cyclase activity|up regulation of cyclase activity Any process that activates or increases the activity of a cyclase. GO:0045817 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045817 GO:0045818 negative regulation of glycogen catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045818 downregulation of glycogen catabolic process|negative regulation of glycogen catabolism|down regulation of glycogen catabolic process|inhibition of glycogen catabolic process|negative regulation of glycogen degradation|negative regulation of glycogen breakdown|down-regulation of glycogen catabolic process|negative regulation of glycogenolysis Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen. GO:0031282 regulation of guanylate cyclase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031282 Any process that modulates the frequency, rate or extent of guanylate cyclase activity. GO:0045815 positive regulation of gene expression, epigenetic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045815 up regulation of gene expression, epigenetic|activation of gene expression, epigenetic|stimulation of gene expression, epigenetic|up-regulation of gene expression, epigenetic|upregulation of gene expression, epigenetic Any epigenetic process that activates or increases the rate of gene expression. GO:0031280 negative regulation of cyclase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031280 inhibition of cyclase activity|down-regulation of cyclase activity|downregulation of cyclase activity|down regulation of cyclase activity Any process that stops or reduces the activity of a cyclase. GO:0045816 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045816 GO:0045813 positive regulation of Wnt signaling pathway, calcium modulating pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045813 stimulation of frizzled-2 signaling pathway|up-regulation of frizzled-2 signaling pathway|activation of frizzled-2 signaling pathway|positive regulation of frizzled-2 signalling pathway|positive regulation of frizzled-2 signaling pathway|up regulation of frizzled-2 signaling pathway|positive regulation of Wnt-activated signaling pathway, calcium modulating pathway|upregulation of frizzled-2 signaling pathway|positive regulation of Wnt receptor signaling pathway, calcium modulating pathway Any process that activates or increases the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC). GO:0045814 negative regulation of gene expression, epigenetic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045814 downregulation of gene expression, epigenetic|down-regulation of gene expression, epigenetic|inhibition of gene expression, epigenetic|down regulation of gene expression, epigenetic Any epigenetic process that stops, prevents or reduces the rate of gene expression. GO:0045811 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045811 GO:0045812 negative regulation of Wnt signaling pathway, calcium modulating pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045812 negative regulation of frizzled-2 signalling pathway|negative regulation of frizzled-2 signaling pathway|down-regulation of frizzled-2 signaling pathway|downregulation of frizzled-2 signaling pathway|negative regulation of Wnt receptor signaling pathway, calcium modulating pathway|down regulation of frizzled-2 signaling pathway|inhibition of frizzled-2 signaling pathway|negative regulation of Wnt-activated signaling pathway, calcium modulating pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC). GO:0031289 actin phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031289 The transfer of one or more phosphate groups to an actin molecule. GO:0031287 positive regulation of sorocarp stalk cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031287 up-regulation of stalk cell differentiation|activation of stalk cell differentiation|positive regulation of stalk cell differentiation|up regulation of stalk cell differentiation|upregulation of stalk cell differentiation|stimulation of stalk cell differentiation Any process that activates or increases the frequency, rate or extent of sorocarp stalk cell differentiation. An example of this process is found in Dictyostelium discoideum. GO:0031288 sorocarp morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031288 fruiting body morphogenesis The process in which the sorocarp is generated and organized. An example of this process is found in Dictyostelium discoideum. GO:0031285 regulation of sorocarp stalk cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031285 regulation of stalk cell differentiation Any process that modulates the frequency, rate or extent of sorocarp stalk cell differentiation. An example of this process is found in Dictyostelium discoideum. GO:0031286 negative regulation of sorocarp stalk cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031286 negative regulation of stalk cell differentiation|down-regulation of stalk cell differentiation|downregulation of stalk cell differentiation|down regulation of stalk cell differentiation|inhibition of stalk cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of sorocarp stalk cell differentiation. An example of this process is found in Dictyostelium discoideum. GO:0031283 negative regulation of guanylate cyclase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031283 down regulation of guanylate cyclase activity|inhibition of guanylate cyclase activity|down-regulation of guanylate cyclase activity|downregulation of guanylate cyclase activity Any process that stops, prevents, or reduces the frequency, rate or extent of guanylate cyclase activity. GO:0045819 positive regulation of glycogen catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045819 upregulation of glycogen catabolic process|stimulation of glycogen catabolic process|up-regulation of glycogen catabolic process|activation of glycogen catabolic process|positive regulation of glycogen degradation|positive regulation of glycogen breakdown|positive regulation of glycogen catabolism|up regulation of glycogen catabolic process|positive regulation of glycogenolysis Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen. GO:0031284 positive regulation of guanylate cyclase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031284 upregulation of guanylate cyclase activity|stimulation of guanylate cyclase activity|up-regulation of guanylate cyclase activity|activation of guanylate cyclase activity|up regulation of guanylate cyclase activity Any process that activates or increases the frequency, rate or extent of guanylate cyclase activity. GO:0045820 negative regulation of glycolytic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045820 downregulation of glycolysis|down regulation of glycolysis|inhibition of glycolysis|down-regulation of glycolysis Any process that stops, prevents, or reduces the frequency, rate or extent of glycolysis. GO:0045821 positive regulation of glycolytic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045821 up regulation of glycolysis|upregulation of glycolysis|stimulation of glycolysis|up-regulation of glycolysis|activation of glycolysis Any process that activates or increases the frequency, rate or extent of glycolysis. GO:0045828 positive regulation of isoprenoid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045828 upregulation of isoprenoid metabolic process|stimulation of isoprenoid metabolic process|up-regulation of isoprenoid metabolic process|activation of isoprenoid metabolic process|up regulation of isoprenoid metabolic process|positive regulation of isoprenoid metabolism Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid. GO:0031270 pseudopodium retraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031270 The myosin-based contraction and retraction of the pseudopodium. GO:0045829 negative regulation of isotype switching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045829 negative regulation of isotype switch recombination|down-regulation of isotype switching|inhibition of isotype switching|negative regulation of class switching|down regulation of isotype switching|downregulation of isotype switching|negative regulation of class switch recombination Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching. GO:0031271 lateral pseudopodium assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031271 lateral pseudopodium formation The extension of a pseudopodium from the lateral area of a cell. GO:0045826 obsolete positive regulation of intermediate filament polymerization and/or depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045826 positive regulation of intermediate filament polymerization and/or depolymerization OBSOLETE. Any process that activates or increases the frequency, rate or extent of intermediate filament polymerization and/or depolymerization. GO:0045827 negative regulation of isoprenoid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045827 down regulation of isoprenoid metabolic process|inhibition of isoprenoid metabolic process|down-regulation of isoprenoid metabolic process|downregulation of isoprenoid metabolic process|negative regulation of isoprenoid metabolism Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid. GO:0045824 negative regulation of innate immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045824 down-regulation of innate immune response|downregulation of innate immune response|down regulation of innate immune response|inhibition of innate immune response Any process that stops, prevents, or reduces the frequency, rate or extent of the innate immune response. GO:0045825 obsolete negative regulation of intermediate filament polymerization and/or depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045825 negative regulation of intermediate filament polymerization and/or depolymerization OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate filament polymerization and/or depolymerization. GO:0045822 negative regulation of heart contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045822 down regulation of heart contraction|downregulation of heart contraction|down-regulation of heart contraction|inhibition of heart contraction|negative regulation of cardiac contraction Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction. GO:0045823 positive regulation of heart contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045823 upregulation of heart contraction|up regulation of heart contraction|activation of heart contraction|stimulation of heart contraction|up-regulation of heart contraction|positive regulation of cardiac contraction Any process that activates or increases the frequency, rate or extent of heart contraction. GO:0031278 alpha-1,2-galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031278 Catalysis of the transfer of a galactose residue from a donor molecule, such as GDP-galactose or UDP-galactose, to an oligosaccharide, forming an alpha-1,2-linkage. GO:0031279 regulation of cyclase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031279 Any process that modulates the frequency, rate or extent of cyclase activity. GO:0031276 negative regulation of lateral pseudopodium assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031276 down-regulation of lateral pseudopodium formation|downregulation of lateral pseudopodium formation|inhibition of lateral pseudopodium formation|negative regulation of lateral pseudopodium formation|down regulation of lateral pseudopodium formation Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of pseudopodia from the lateral side of the cell. GO:0031277 positive regulation of lateral pseudopodium assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031277 upregulation of lateral pseudopodium formation|stimulation of lateral pseudopodium formation|activation of lateral pseudopodium formation|up-regulation of lateral pseudopodium formation|positive regulation of lateral pseudopodium formation|up regulation of lateral pseudopodium formation Any process that activates or increases the frequency, rate or extent of the assembly of pseudopodia from the lateral side of the cell. GO:0031274 positive regulation of pseudopodium assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031274 positive regulation of pseudopodium formation|upregulation of pseudopodium formation|stimulation of pseudopodium formation|activation of pseudopodium formation|up-regulation of pseudopodium formation|up regulation of pseudopodium formation Any process that activates or increases the frequency, rate or extent of the assembly of pseudopodia. GO:0031275 regulation of lateral pseudopodium assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031275 regulation of lateral pseudopodium formation Any process that modulates the frequency, rate or extent of the assembly of pseudopodia from the lateral side of the cell. GO:0031272 regulation of pseudopodium assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031272 regulation of pseudopodium formation Any process that modulates the frequency, rate or extent of the assembly of pseudopodia. GO:0031273 negative regulation of pseudopodium assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031273 downregulation of pseudopodium formation|inhibition of pseudopodium formation|down regulation of pseudopodium formation|negative regulation of pseudopodium formation|down-regulation of pseudopodium formation Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of pseudopodia. GO:0031269 pseudopodium assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031269 pseudopodium formation|pseudopodium extension The assembly of a pseudopodium by rearrangement of the actin cytoskeleton and overlying membrane. GO:0045831 negative regulation of light-activated channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045831 down-regulation of light-activated channel activity|downregulation of light-activated channel activity|down regulation of light-activated channel activity|inhibition of light-activated channel activity Any process that stops, prevents, or reduces the frequency, rate or extent of light-activated channel activity. GO:0045832 positive regulation of light-activated channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045832 stimulation of light-activated channel activity|up-regulation of light-activated channel activity|activation of light-activated channel activity|up regulation of light-activated channel activity|upregulation of light-activated channel activity Any process that activates or increases the frequency, rate or extent of light-activated channel activity. GO:0045830 positive regulation of isotype switching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045830 up regulation of isotype switching|activation of isotype switching|positive regulation of class switch recombination|stimulation of isotype switching|positive regulation of class switching|positive regulation of isotype switch recombination|up-regulation of isotype switching|upregulation of isotype switching Any process that activates or increases the frequency, rate or extent of isotype switching. GO:0045839 negative regulation of mitotic nuclear division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045839 down regulation of mitosis|downregulation of mitosis|negative regulation of mitosis|down-regulation of mitosis|inhibition of mitosis Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother. GO:0031260 pseudopodium membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031260 The portion of the plasma membrane surrounding a pseudopodium. GO:0045837 negative regulation of membrane potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045837 reduction of membrane potential|down-regulation of membrane potential|downregulation of membrane potential|down regulation of membrane potential|inhibition of membrane potential Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. GO:0045838 positive regulation of membrane potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045838 elevation of membrane potential|stimulation of membrane potential|up-regulation of membrane potential|activation of membrane potential|up regulation of membrane potential|upregulation of membrane potential Any process that activates or increases the frequency, rate or extent of establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. PR:000007565 vascular endothelial growth factor receptor 3 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000007565 FLT-4|VEGFR-3|tyrosine-protein kinase receptor FLT4|FLT4|Fms-like tyrosine kinase 4 A vascular endothelial growth factor receptor that is a translation product of the human FLT4 gene or a 1:1 ortholog thereof. GO:0045835 negative regulation of meiotic nuclear division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045835 inhibition of meiosis|down regulation of meiosis|downregulation of meiosis|negative regulation of meiosis|down-regulation of meiosis Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis. GO:0045836 positive regulation of meiotic nuclear division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045836 up-regulation of meiosis|upregulation of meiosis|up regulation of meiosis|activation of meiosis|positive regulation of meiosis|stimulation of meiosis Any process that activates or increases the frequency, rate or extent of meiosis. GO:0045833 negative regulation of lipid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045833 downregulation of lipid metabolic process|negative regulation of lipid metabolism|down-regulation of lipid metabolic process|inhibition of lipid metabolic process|down regulation of lipid metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids. GO:0045834 positive regulation of lipid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045834 up regulation of lipid metabolic process|activation of lipid metabolic process|positive regulation of lipid metabolism|stimulation of lipid metabolic process|up-regulation of lipid metabolic process|upregulation of lipid metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids. GO:0031267 small GTPase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031267 Rab interactor activity|Ran protein binding|Rab escort protein activity|Rab GTPase binding|Rac GTPase binding|ADP-ribosylation factor binding|REP|Rho GTPase binding|Ran-binding protein|Ras interactor activity|ARF binding|Ral GTPase binding|GTP-Ral binding|Ran GTPase binding|GTP-Rho binding|Ras GTPase binding Interacting selectively and non-covalently with a small monomeric GTPase. GO:0031268 pseudopodium organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031268 pseudopodium organization and biogenesis|pseudopodium organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pseudopodium, a temporary protrusion or retractile process of a cell, associated with cellular movement. GO:0031265 CD95 death-inducing signaling complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031265 Fas death-inducing signaling complex|CD95 death-inducing signalling complex|CD95 DISC A protein complex formed upon binding of Fas/CD95/APO-1 to its ligand. The complex includes FADD/Mort1, procaspase-8/10 and c-FLIP in addition to the ligand-bound receptor. GO:0031266 TRAIL death-inducing signaling complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031266 TRAIL DISC|TRAIL death-inducing signalling complex A protein complex formed upon binding of TRAIL to its ligand. The complex includes FADD/Mort1 and procaspase-8 addition to the ligand-bound receptor. GO:0031263 obsolete ATPase-coupled amine transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031263 amine-transporting ATPase activity|ATP-dependent amine transporter activity|amine ABC transporter OBSOLETE. Catalysis of the reaction: ATP + H2O + amine(out) = ADP + phosphate + amine(in). GO:0031264 death-inducing signaling complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0031264 Wikipedia:Death-inducing_signaling_complex DISC protein complex|death receptor-induced signalling complex|death-inducing signalling complex|DISC|death receptor-induced signaling complex A protein complex formed by the association of signaling proteins with a death receptor upon ligand binding. The complex includes procaspases and death domain-containing proteins in addition to the ligand-bound receptor, and may control the activation of caspases 8 and 10. GO:0031261 DNA replication preinitiation complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031261 pre-IC A protein-DNA complex assembled at eukaryotic DNA replication origins immediately prior to the initiation of DNA replication. The preinitiation complex is formed by the assembly of additional proteins onto an existing prereplicative complex. In budding yeast, the additional proteins might include Cdc45p, Sld2p, Sld3p, Dpb11p, DNA polymerases, and others; in fission yeast the GINS complex is present. GO:0031262 Ndc80 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031262 Nuf2-Ndc80 complex An outer kinetochore protein complex that is part of the KMN kinetochore network (also known as the NMS complex) providing the platform with which the plus ends of spindle microtubules directly interact to form stable kinetochore-microtubule attachments. A common subunit nomenclature is used from yeast to human: Ndc80, Nuf2, Spc24, and Spc25. GO:0031258 lamellipodium membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031258 The portion of the plasma membrane surrounding a lamellipodium. GO:0031259 uropod membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031259 uropodium membrane The portion of the plasma membrane surrounding a uropod. GO:0045842 positive regulation of mitotic metaphase/anaphase transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045842 up-regulation of mitotic metaphase/anaphase transition|upregulation of mitotic metaphase/anaphase transition|up regulation of mitotic metaphase/anaphase transition|activation of mitotic metaphase/anaphase transition|stimulation of mitotic metaphase/anaphase transition Any process that activates or increases the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin. GO:0045843 negative regulation of striated muscle tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045843 down-regulation of striated muscle development|inhibition of striated muscle development|down regulation of striated muscle development|downregulation of striated muscle development Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle development. GO:0045840 positive regulation of mitotic nuclear division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045840 mitogenic activity|up-regulation of mitosis|upregulation of mitosis|up regulation of mitosis|activation of mitosis|positive regulation of mitosis|stimulation of mitosis Any process that activates or increases the frequency, rate or extent of mitosis. GO:0045841 negative regulation of mitotic metaphase/anaphase transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045841 inhibition of mitotic metaphase/anaphase transition|down regulation of mitotic metaphase/anaphase transition|downregulation of mitotic metaphase/anaphase transition|down-regulation of mitotic metaphase/anaphase transition Any process that stops, prevents, or reduces the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin. PR:000007581 fibronectin biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000007581 cold-insoluble globulin|FN1|FN|CIG A protein that is a translation product of the human FN1 gene or a 1:1 ortholog thereof. CHEBI:81243 alpha-muricholic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_81243 CHEBI:81244 hyocholic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_81244 GO:0045848 positive regulation of nitrogen utilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045848 upregulation of nitrogen utilization|stimulation of nitrogen utilization|up-regulation of nitrogen utilization|activation of nitrogen utilization|up regulation of nitrogen utilization Any process that activates or increases the frequency, rate or extent of nitrogen utilization. GO:0045849 negative regulation of nurse cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045849 downregulation of nurse cell apoptosis|down regulation of nurse cell apoptosis|inhibition of nurse cell apoptosis|negative regulation of nurse cell apoptosis|down-regulation of nurse cell apoptosis Any process that stops, prevents, or reduces the frequency, rate or extent of nurse cell apoptotic process. CHEBI:81240 ursocholic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_81240 GO:0045846 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045846 GO:0045847 negative regulation of nitrogen utilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045847 inhibition of nitrogen utilization|down-regulation of nitrogen utilization|downregulation of nitrogen utilization|down regulation of nitrogen utilization Any process that stops, prevents, or reduces the frequency, rate or extent of nitrogen utilization. GO:0045844 positive regulation of striated muscle tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045844 up regulation of striated muscle development|activation of striated muscle development|stimulation of striated muscle development|up-regulation of striated muscle development|upregulation of striated muscle development Any process that activates or increases the frequency, rate or extent of striated muscle development. GO:0045845 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045845 GO:0031256 leading edge membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031256 The portion of the plasma membrane surrounding the leading edge of a motile cell. GO:0031257 cell trailing edge membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031257 trailing edge membrane The portion of the plasma membrane surrounding the trailing edge of a motile cell. GO:0031254 cell trailing edge biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0031254 trailing edge|back of cell The area of a motile cell opposite to the direction of movement. GO:0031255 lateral part of motile cell biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031255 The area of a motile cell perpendicular to the direction of movement. GO:0031252 cell leading edge biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0031252 front of cell|leading edge of cell The area of a motile cell closest to the direction of movement. GO:0031253 cell projection membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031253 membrane projection|membrane extension The portion of the plasma membrane surrounding a plasma membrane bounded cell surface projection. GO:0031250 anaerobic ribonucleoside-triphosphate reductase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031250 An enzyme complex composed of 4 subunits, 2 copies of the large protein (nrdD in E. coli) and 2 copies of the small protein (nrdG in E. coli). It catalyzes the generation of 2'deoxyribonucleotides under anaerobic growth conditions. The larger subunit is the catalytic unit that is activated by the smaller iron-binding subunit. GO:0031251 PAN complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031251 poly(A) nuclease complex A complex that possesses poly(A)-specific ribonuclease activity; catalyzes the message-specific shortening of mRNA poly(A) tails. Contains at least two subunits, known as Pan2p and Pan3p in Saccharomyces. GO:0031249 denatured protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031249 Interacting selectively and non-covalently with denatured proteins. GO:0031247 actin rod assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031247 actin rod formation The assembly of actin rods, a cellular structure consisting of parallel, hexagonally arranged actin tubules. GO:0031248 protein acetyltransferase complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0031248 A complex that catalyzes the transfer of an acetyl group to a protein acceptor molecule. GO:0006289 nucleotide-excision repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006289 intrastrand cross-link repair|NER|pyrimidine-dimer repair, DNA damage excision A DNA repair process in which a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts). GO:0045853 negative regulation of bicoid mRNA localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045853 negative regulation of bicoid mRNA localisation|down-regulation of bicoid mRNA localization|downregulation of bicoid mRNA localization|down regulation of bicoid mRNA localization|inhibition of bicoid mRNA localization Any process that stops, prevents, or reduces the frequency, rate or extent of the process in which bicoid mRNA is transported to, or maintained in, a specific location. GO:0045854 positive regulation of bicoid mRNA localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045854 stimulation of bicoid mRNA localization|up-regulation of bicoid mRNA localization|activation of bicoid mRNA localization|positive regulation of bicoid mRNA localisation|up regulation of bicoid mRNA localization|upregulation of bicoid mRNA localization Any process that activates or increases the frequency, rate or extent of the process in which bicoid mRNA is transported to, or maintained in, a specific location. GO:0045851 pH reduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045851 acidification Any process that reduces the internal pH of an organism, part of an organism or a cell, measured by the concentration of the hydrogen ion. GO:0006287 base-excision repair, gap-filling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006287 Repair of the damaged strand by the combined action of an apurinic endouclease that degrades a few bases on the damaged strand and a polymerase that synthesizes a 'patch' in the 5' to 3' direction, using the undamaged strand as a template. GO:0045852 pH elevation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045852 Any process that increases the internal pH of an organism, part of an organism or a cell, measured by the concentration of the hydrogen ion. GO:0006288 base-excision repair, DNA ligation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006288 The ligation by DNA ligase of DNA strands. Ligation occurs after polymerase action to fill the gap left by the action of endonucleases during base-excision repair. GO:0006285 base-excision repair, AP site formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006285 The formation of an AP site, a deoxyribose sugar with a missing base, by DNA glycosylase which recognizes an altered base in DNA and catalyzes its hydrolytic removal. This sugar phosphate is the substrate recognized by the AP endonuclease, which cuts the DNA phosphodiester backbone at the 5' side of the altered site to leave a gap which is subsequently repaired. GO:0045850 positive regulation of nurse cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045850 positive regulation of nurse cell apoptosis|up regulation of nurse cell apoptosis|upregulation of nurse cell apoptosis|stimulation of nurse cell apoptosis|activation of nurse cell apoptosis|up-regulation of nurse cell apoptosis Any process that activates or increases the frequency, rate or extent of nurse cell apoptotic process. GO:0006286 base-excision repair, base-free sugar-phosphate removal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006286 Excision of the sugar phosphate residue at an AP site, i.e. a deoxyribose sugar with a missing base, by a phosphodiesterase enzyme. GO:0006283 transcription-coupled nucleotide-excision repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006283 TC-NER|transcription-coupled NER|transcription-coupled repair|TCR The nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway. GO:0070808 regulation of Hulle cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070808 Any process that modulates the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body. GO:0006284 base-excision repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006284 Wikipedia:Base_excision_repair BER In base excision repair, an altered base is removed by a DNA glycosylase enzyme, followed by excision of the resulting sugar phosphate. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. GO:0070809 negative regulation of Hulle cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070809 Any process that stops, prevents, or reduces the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body. GO:0070817 P-TEFb-cap methyltransferase complex localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070817 establishment and maintenance of P-TEFb-cap methyltransferase complex localization|P-TEFb-cap methyltransferase complex localisation Any process in which the P-TEFb-cap methyltransferase complex is transported to, or maintained in, a specific location. GO:0006292 obsolete pyrimidine-dimer repair, DNA damage recognition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006292 pyrimidine-dimer repair, DNA damage recognition OBSOLETE. The location of pyrimidine dimers by a large multienzyme complex that scans the DNA for distortions in the double helix caused by pyrimidine dimers. GO:0070818 protoporphyrinogen oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070818 protoporphyrinogenase activity|protoporphyrinogen IX oxidase activity|protoporphyrinogen-IX oxidase activity Catalysis of the reaction: protoporphyrinogen IX + acceptor = protoporphyrin IX + reduced acceptor. GO:0006293 nucleotide-excision repair, preincision complex stabilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006293 The stabilization of the multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage as well as the unwound DNA. The stabilization of the protein-DNA complex ensures proper positioning of the preincision complex before the phosphodiester backbone of the damaged strand is cleaved 3' and 5' of the site of DNA damage. CHEBI:81253 isolithocholic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_81253 GO:0070815 peptidyl-lysine 5-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070815 peptidyl-lysine, 2-oxoglutarate: oxygen oxidoreductase activity|peptide-lysine 5-dioxygenase activity|protein lysine hydroxylase activity|lysyl hydroxylase activity|peptidyllysine, 2-oxoglutarate:oxygen 5-oxidoreductase activity|lysine hydroxylase activity|lysine-2-oxoglutarate dioxygenase activity|lysine,2-oxoglutarate 5-dioxygenase activity Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 5-hydroxy-L-lysine + succinate + CO2. GO:0045859 regulation of protein kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045859 Any process that modulates the frequency, rate or extent of protein kinase activity. GO:0006290 pyrimidine dimer repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006290 The repair of UV-induced T-T, C-T and C-C dimers. GO:0070816 phosphorylation of RNA polymerase II C-terminal domain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070816 CTD domain phosphorylation of RNA polymerase II|generation of hyperphosphorylated CTD of RNA polymerase II|hyperphosphorylation of RNA polymerase II C-terminal domain|generation of II(0) form of RNA polymerase II The process of introducing a phosphate group on to an amino acid residue in the C-terminal domain of RNA polymerase II. Typically, this occurs during the transcription cycle and results in production of an RNA polymerase II enzyme where the carboxy-terminal domain (CTD) of the largest subunit is extensively phosphorylated, often referred to as hyperphosphorylated or the II(0) form. Specific types of phosphorylation within the CTD are usually associated with specific regions of genes, though there are exceptions. The phosphorylation state regulates the association of specific complexes such as the capping enzyme or 3'-RNA processing machinery to the elongating RNA polymerase complex. GO:0006291 obsolete pyrimidine-dimer repair, DNA damage excision biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006291 pyrimidine-dimer repair, DNA damage excision OBSOLETE. The excision of damaged DNA during pyrimidine-dimer repair. A large multienzyme complex scans the DNA for a distortion in the double helix rather than for a specific base change. Once a bulky lesion is found, the phosphodiester backbone of the abnormal strand is cleaved on both sides of the distortion, and the portion of the strand containing the lesion (an oligonucleotide) is peeled away from the DNA double helix by a DNA helicase enzyme. GO:0045857 negative regulation of molecular function, epigenetic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045857 down-regulation of protein activity, epigenetic|downregulation of protein activity, epigenetic|down regulation of protein activity, epigenetic|inhibition of protein activity, epigenetic|negative regulation of protein activity, epigenetic Any heritable epigenetic process that stops, prevents, or reduces the frequency, rate or extent of protein function by self-perpetuating conformational conversions of normal proteins in healthy cells. This is distinct from, though mechanistically analogous to, disease states associated with prion propagation and amyloidogenesis. A single protein, if it carries a glutamine/asparagine-rich ('prion') domain, can sometimes stably exist in at least two distinct physical states, each associated with a different phenotype; propagation of one of these traits is achieved by a self-perpetuating change in the protein from one form to the other, mediated by conformational changes in the glutamine/asparagine-rich domain. Prion domains are both modular and transferable to other proteins, on which they can confer a heritable epigenetic alteration of function; existing bioinformatics data indicate that they are rare in non-eukarya, but common in eukarya. GO:0070813 hydrogen sulfide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070813 hydrogen sulphide metabolism|hydrogen sulfide metabolism|hydrogen sulphide metabolic process The chemical reactions and pathways involving hydrogen sulfide, H2S. GO:0070814 hydrogen sulfide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070814 hydrogen sulfide anabolism|hydrogen sulphide biosynthesis|hydrogen sulphide biosynthetic process|hydrogen sulfide synthesis|hydrogen sulfide formation|hydrogen sulfide biosynthesis The chemical reactions and pathways resulting in the formation of hydrogen sulfide, H2S. GO:0045858 positive regulation of molecular function, epigenetic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045858 up regulation of protein activity, epigenetic|upregulation of protein activity, epigenetic|stimulation of protein activity, epigenetic|up-regulation of protein activity, epigenetic|positive regulation of protein activity, epigenetic|activation of protein activity, epigenetic Any heritable epigenetic process that increases the frequency, rate or extent of protein function by self-perpetuating conformational conversions of normal proteins in healthy cells. This is distinct from, though mechanistically analogous to, disease states associated with prion propagation and amyloidogenesis. A single protein, if it carries a glutamine/asparagine-rich ('prion') domain, can sometimes stably exist in at least two distinct physical states, each associated with a different phenotype; propagation of one of these traits is achieved by a self-perpetuating change in the protein from one form to the other, mediated by conformational changes in the glutamine/asparagine-rich domain. Prion domains are both modular and transferable to other proteins, on which they can confer a heritable epigenetic alteration of function; existing bioinformatics data indicate that they are rare in non-eukarya, but common in eukarya. GO:0070811 glycerol-2-phosphate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070811 glycerol-2-phosphate transport The process in which glycerol-2-phosphate is transported across a membrane. Glycerol-2-phosphate is a phosphoric monoester of glycerol. GO:0045855 negative regulation of pole plasm oskar mRNA localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045855 negative regulation of pole plasm oskar mRNA localisation|down-regulation of pole plasm oskar mRNA localization|negative regulation of oocyte pole plasm oskar mRNA localization|downregulation of pole plasm oskar mRNA localization|down regulation of pole plasm oskar mRNA localization|inhibition of pole plasm oskar mRNA localization Any process that stops, prevents, or reduces the frequency, rate or extent of a process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm. GO:0045856 positive regulation of pole plasm oskar mRNA localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045856 stimulation of pole plasm oskar mRNA localization|up-regulation of pole plasm oskar mRNA localization|activation of pole plasm oskar mRNA localization|positive regulation of oocyte pole plasm oskar mRNA localization|positive regulation of pole plasm oskar mRNA localisation|up regulation of pole plasm oskar mRNA localization|upregulation of pole plasm oskar mRNA localization Any process that activates or increases the frequency, rate or extent of the process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm. GO:0070812 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0070812 GO:0031245 extrinsic component of periplasmic side of cell outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031245 extrinsic to internal side of cell outer membrane|extrinsic to internal leaflet of cell outer membrane|extrinsic to periplasmic side of cell outer membrane|extrinsic to internal side of outer membrane The component of the cell outer membrane consisting of gene products and protein complexes that are loosely bound to periplasmic surface, but not integrated into the hydrophobic region. GO:0031246 intrinsic component of periplasmic side of cell outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031246 intrinsic to internal side of outer membrane|intrinsic to external side of cell outer membrane|intrinsic to internal side of cell outer membrane|intrinsic to internal leaflet of cell outer membrane The component of the cell outer membrane consisting of the gene products that that penetrate the periplasmic side of the cell outer membrane only, either directly or via some covalently attached hydrophobic anchor. GO:0070810 positive regulation of Hulle cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070810 Any process that activates or increases the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body. GO:0031243 intrinsic component of external side of cell outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031243 intrinsic to external side of cell outer membrane|intrinsic to external leaflet of cell outer membrane|intrinsic to external side of outer membrane The component of the cell outer membrane consisting of the gene products and protein complexes that penetrate the external side of the cell outer membrane only, either directly or via some covalently attached hydrophobic anchor. GO:0031244 extrinsic component of cell outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031244 extrinsic to cell outer membrane The component of the cell outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:0031241 periplasmic side of cell outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031241 internal leaflet of cell outer membrane|internal side of outer membrane|internal side of cell outer membrane The side (leaflet) of the outer membrane that faces the periplasm of the cell. GO:0031242 extrinsic component of external side of cell outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031242 extrinsic to external side of outer membrane|extrinsic to external side of cell outer membrane|extrinsic to external leaflet of cell outer membrane The component of a cell outer membrane consisting of gene products and protein complexes that are loosely bound to its external surface, but not integrated into the hydrophobic region. GO:0031240 external side of cell outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031240 external side of outer membrane|external leaflet of cell outer membrane The side of the outer membrane that is opposite to the side that faces the periplasm of the cell. GO:0031238 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031238 GO:0031239 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031239 GO:0031236 extrinsic component of periplasmic side of plasma membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031236 extrinsic to external side of plasma membrane, in periplasmic space|extrinsic to external leaflet of plasma membrane, in periplasmic space The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its periplasmic surface, but not integrated into the hydrophobic region. GO:0031237 intrinsic component of periplasmic side of plasma membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031237 intrinsic to external leaflet of plasma membrane, in periplasmic space|intrinsic to periplasmic side of plasma membrane The component of a plasma membrane consisting of gene products and protein complexes that penetrate the periplasmic side of the plasma membrane only, either directly or via some covalently attached hydrophobic anchor. GO:0045864 positive regulation of pteridine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045864 up regulation of pteridine metabolic process|activation of pteridine metabolic process|stimulation of pteridine metabolic process|up-regulation of pteridine metabolic process|positive regulation of pteridine metabolism|upregulation of pteridine metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving pteridine. GO:0045865 obsolete regulation of recombination within rDNA repeats biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045865 regulation of recombination within rDNA repeats OBSOLETE. Any process that modulates the frequency, rate or extent of genetic recombination within the DNA of the genes coding for ribosomal RNA. GO:0045862 positive regulation of proteolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045862 activation of proteolysis|stimulation of proteolysis|up-regulation of proteolysis|upregulation of proteolysis|positive regulation of peptidolysis|up regulation of proteolysis Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein. GO:0006298 mismatch repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006298 Wikipedia:DNA_mismatch_repair mismatch repair, MutL-like pathway|MMR|long patch mismatch repair system|MutS/MutL/MutH pathway A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination. PR:000007563 vascular endothelial growth factor receptor 1 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000007563 embryonic receptor kinase 2|FLT-1|tyrosine-protein kinase receptor FLT|Emrk2|FLT|VEGFR-1|tyrosine-protein kinase FRT|FRT|FLT1|vascular permeability factor receptor|Fms-like tyrosine kinase 1 A vascular endothelial growth factor receptor that is a translation product of the human FLT1 gene or a 1:1 ortholog thereof. GO:0045863 negative regulation of pteridine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045863 down regulation of pteridine metabolic process|downregulation of pteridine metabolic process|down-regulation of pteridine metabolic process|negative regulation of pteridine metabolism|inhibition of pteridine metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving pteridine. GO:0006299 obsolete short patch mismatch repair system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006299 short patch mismatch repair system OBSOLETE. The repair of mismatched DNA where the gap to be repaired is only one nucleotide. DNA polymerase is the preferred polymerase in short patch repair, performing gap filling DNA synthesis and removal of the 5'-deoxyribose phosphate of the abasic site. GO:0045860 positive regulation of protein kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045860 upregulation of protein kinase activity|up regulation of protein kinase activity|stimulation of protein kinase activity|up-regulation of protein kinase activity Any process that activates or increases the frequency, rate or extent of protein kinase activity. GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006296 nucleotide-excision repair, DNA incision, 5' to lesion The endonucleolytic cleavage of the damaged strand of DNA 5' to the site of damage. The incision occurs at the junction of single-stranded DNA and double-stranded DNA that is formed when the DNA duplex is unwound. The incision follows the incision formed 3' to the site of damage. GO:0006297 nucleotide-excision repair, DNA gap filling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006297 Repair of the gap in the DNA helix by DNA polymerase and DNA ligase after the portion of the strand containing the lesion has been removed by pyrimidine-dimer repair enzymes. GO:0045861 negative regulation of proteolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045861 down-regulation of proteolysis|inhibition of proteolysis|negative regulation of peptidolysis|down regulation of proteolysis|downregulation of proteolysis Any process that stops, prevents, or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein. GO:0006294 nucleotide-excision repair, preincision complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006294 nucleotide-excision repair, preincision complex formation The aggregation, arrangement and bonding together of proteins on DNA to form the multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage. This assembly occurs before the phosphodiester backbone of the damaged strand is cleaved 3' and 5' of the site of DNA damage. GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006295 nucleotide-excision repair, DNA incision, 3' to lesion The endonucleolytic cleavage of the damaged strand of DNA 3' to the site of damage. The incision occurs at the junction of single-stranded DNA and double-stranded DNA that is formed when the DNA duplex is unwound. The incision precedes the incision formed 5' to the site of damage. GO:0070806 negative regulation of phialide development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070806 Any process that stops, prevents, or reduces the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip. GO:0070807 positive regulation of phialide development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070807 Any process that activates or increases the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip. GO:0070804 positive regulation of metula development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070804 Any process that activates or increases the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip. GO:0070805 regulation of phialide development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070805 Any process that modulates the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip. GO:0045868 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045868 GO:0070802 regulation of metula development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070802 Any process that modulates the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip. PR:000007555 filamin-A biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000007555 FLN1|FLN|filamin-1|FLN-A|actin-binding protein 280|FLNA|endothelial actin-binding protein|ABP-280|non-muscle filamin|alpha-filamin A protein that is a translation product of the human FLNA gene or a 1:1 ortholog thereof. GO:0045869 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045869 down regulation of retroviral genome replication|downregulation of retroviral genome replication|regulation of retroviral genome replication|down-regulation of retroviral genome replication|negative regulation of retroviral genome replication|inhibition of retroviral genome replication Any process that stops, prevents, or reduces the frequency, rate or extent of single stranded viral RNA replication via double stranded DNA intermediate. GO:0070803 negative regulation of metula development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070803 Any process that stops, prevents, or reduces the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip. PR:000007556 filamin-B biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000007556 ABP-280 homolog|FLN3|filamin homolog 1|filamin-3|TAP|FLN1L|beta-filamin|FLN-B|thyroid autoantigen|FLNB|ABP-280-like protein|TABP|ABP-278|truncated actin-binding protein|Fh1|truncated ABP|actin-binding-like protein A protein that is a translation product of the human FLNB gene or a 1:1 ortholog thereof. GO:0070800 negative regulation of conidiophore stalk development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070800 Any process that stops, prevents, or reduces the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop. GO:0045866 obsolete positive regulation of recombination within rDNA repeats biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045866 positive regulation of recombination within rDNA repeats OBSOLETE. Any process that activates or increases the frequency, rate or extent of genetic recombination within the DNA of the genes coding for ribosomal RNA. GO:0045867 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045867 PR:000007557 filamin-C biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000007557 FLN2|filamin-2|FLN-C|FLNC|FLNc|ABPL|ABP-280-like protein|gamma-filamin|ABP-L|actin-binding-like protein A protein that is a translation product of the human FLNC gene or a 1:1 ortholog thereof. GO:0070801 positive regulation of conidiophore stalk development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070801 Any process that activates or increases the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop. GO:0031234 extrinsic component of cytoplasmic side of plasma membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031234 extrinsic to internal leaflet of plasma membrane|extrinsic to cytoplasmic side of plasma membrane|extrinsic to internal side of plasma membrane The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its cytoplasmic surface, but not integrated into the hydrophobic region. GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031235 intrinsic to internal side of plasma membrane|intrinsic to internal leaflet of plasma membrane|intrinsic to cytoplasmic side of plasma membrane The component of a plasma membrane consisting of gene products and protein complexes that have some covalently attached part (e.g. peptide sequence or GPI anchor) which is embedded in the cytoplasmic side of the plasma membrane only. GO:0031232 extrinsic component of external side of plasma membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031232 extrinsic to external side of plasma membrane|extrinsic to external leaflet of plasma membrane The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its external surface, but not integrated into the hydrophobic region. GO:0031233 intrinsic component of external side of plasma membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031233 intrinsic to external side of plasma membrane|intrinsic to external leaflet of plasma membrane The component of a plasma membrane consisting of gene products and protein complexes that penetrate the external side of the plasma membrane only, either directly or via some covalently attached hydrophobic anchor. GO:0031230 intrinsic component of cell outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031230 intrinsic to cell outer membrane The component of the cell outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0031231 intrinsic component of peroxisomal membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031231 intrinsic to peroxisomal membrane The component of the peroxisomal membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. CHEBI:22860 amino-acid betaine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22860 CHEBI:46832 3-carboxypyridine-2-carboxylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46832 CHEBI:46833 2-carboxypyridine-3-carboxylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46833 GO:0080193 diffuse secondary thickening biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080193 Lateral growth of the older parts of a stem that occurs when the central parenchyma cells and the not yet fully differentiated fiber cells of the bundle sheaths continue to undergo cell division and expansion for a long period of time, leading to an increase in girth of the stem. UBERON:0003296 gland of diencephalon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003296 interbrain gland|diencephalon gland Any gland that is part of the diencephalon. Examples: pineal gland, neurohypophysis. UBERON:0003297 gland of integumental system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003297 integumentary gland|integumental system gland|integumental gland A gland that is part of a integumental system [Automatically generated definition]. UBERON:0003294 gland of foregut biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003294 foregut gland A gland that is part of a foregut [Automatically generated definition]. UBERON:0003295 pharyngeal gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003295 glandulae pharyngeae|pharynx gland Racemose mucous glands beneath the mucous membrane of the pharynx. UBERON:0003292 meninx of spinal cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003292 spinal meninx|meninges of spinal cord|spinal meninges|spinal cord meninx|spinal cord meninges|menines of spinal cord A meninx that is part of a spinal cord [Automatically generated definition]. GO:0080190 lateral growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080190 Growth of a plant axis (shoot axis or root) that originates from a lateral meristem. UBERON:0003290 meninx of diencephalon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003290 meninx of between brain|meninges of diencephalon|mature diencephalon meninx|mature diencephalon meninges|diencephalon meninx|diencephalon meninges|meninges of mature diencephalon|meninx of mature diencephalon|interbrain meninx|meninx of interbrain|interbrain meninges|between brain meninx|meninges of interbrain|between brain meninges|meninges of between brain A meninx that is part of a diencephalon [Automatically generated definition]. GO:0080191 secondary thickening biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080191 Lateral growth of a plant axis (shoot axis or root) that is an increase in thickness resulting from formation of tissue from a secondary thickening meristem. UBERON:0003291 meninx of hindbrain biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003291 rhomencephalon meninges|hindbrain meninx|meninges of hindbrain|hindbrain meninges A meninx that is part of a hindbrain [Automatically generated definition]. GO:0080192 primary thickening biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080192 Lateral growth of a plant axis (shoot axis or root) that is an increase in thickness resulting from the activity of a primary thickening meristem. CHEBI:46835 dipicolinate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46835 CHEBI:22869 bilins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22869 CHEBI:22866 bilanes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22866 CHEBI:46837 dipicolinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46837 CHEBI:46838 cyclic carbonate ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46838 UBERON:0003299 roof plate of midbrain biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003299 midbrain roof plate|roofplate of midbrain|midbrain roofplate|roof plate midbrain region|roof plate mesencephalon|roofplate midbrain|roof plate midbrain|midbrain roof the mesencephalic roof plate, including the caudal and rostral part of the midbrain roof CHEBI:22872 (glucosyluronic acid)bilirubin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22872 CHEBI:46820 2,6,8-trihydroxypurin-7-ide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46820 CHEBI:46821 6,8-dioxo-6,7,8,9-tetrahydro-1H-purin-2-olate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46821 CHEBI:46822 2,8-dihydroxy-1H-purin-6-olate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46822 CHEBI:46823 1H-purine-2,6,8-triol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46823 CHEBI:4806 (-)-epigallocatechin 3-gallate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_4806 GO:0080186 developmental vegetative growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080186 The increase in size or mass of non-reproductive plant parts. GO:0080187 floral organ senescence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080187 An organ senescence that has as a participant a floral organ. GO:0080188 gene silencing by RNA-directed DNA methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080188 RNA-directed DNA methylation|RdDM An epigenetic RNA-based gene silencing process first elucidated in plants whereby 24-nt small interfering RNAs (siRNAs) guide DNA methyltransferases to the siRNA-generating genomic loci and other loci that are homologous to the siRNAs for de novo DNA methylation. In general this process consists of three phases: biogenesis of siRNAs, scaffold RNA production, and the formation of the guiding complex that recruits de novo DNA methyltransferases to the target loci. GO:0080189 primary growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080189 Growth of a plant structure from the time of its initiation by an apical meristem until its expansion is completed. GO:0080182 histone H3-K4 trimethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080182 The modification of histone H3 by addition of three methyl groups to lysine at position 4 of the histone. GO:0080183 response to photooxidative stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080183 Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as the result of a photooxidative stress, the light-dependent generation of active oxygen species. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. UBERON:0003283 mesentery of oesophagus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003283 oesophagus mesentery|meso-esophagus|mesentery of gullet|esophagus mesentery|gullet mesentery|mesentery of esophagus A mesentery that is part of a esophagus [Automatically generated definition]. GO:0080184 response to phenylpropanoid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080184 Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as the result of a phenylpropanoid stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. A phenylpropanoid is any of secondary metabolites with structures based on a phenylpropane skeleton. The class includes phenylpropanoid esters, flavonoids, anthocyanins, coumarins and many small phenolic molecules. Phenylpropanoids are also precursors of lignin. GO:0080185 effector-mediated induction of plant hypersensitive response by symbiont biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080185 induction of effector-triggered immunity (ETI)|necrotrophic effector|induction by organism of resistance gene-dependent defense response of other organism involved in symbiotic interaction|positive regulation by symbiont of plant hypersensitive response|activation by organism of defense response in host by specific elicitors|effector-triggered induction of host innate immune response|induction by symbiont of host resistance gene-dependent defense response|activation by organism of host resistance gene-dependent defense response|ETI-triggered of host innate immune response|positive regulation by organism of defense response in host by specific elicitors|positive regulation by organism of host gene-for-gene resistance|activation of HR|effector-triggered immunity|activation by organism of host gene-for-gene resistance|effector-triggered induction of plant hypersensitive response by symbiont|positive regulation by symbiont of plant HR|ETI triggered of host innate immune response|avirulence protein|induction by organism of defense response in host by specific elicitors|effector-triggered necrosis|activation by symbiont of host resistance gene-dependent defense response|positive regulation by symbiont of host resistance gene-dependent defense response|induction by organism of pathogen-race/host plant cultivar-specific resistance in host|induction by organism of host gene-for-gene resistance|activation of hypersensitive response A symbiont process in which a molecule secreted by the symbiont activates a resistance gene-dependent defense response signaling pathway in the plant host, in order to activate a hypersensitive response to induce necrosis. In the plant, this process involves the direct or indirect recognition of the symbiont effector protein for example through plant resistance receptor or R proteins (or R genes). UBERON:0003284 mesentery of midgut biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003284 midgut mesentery A mesentery that is part of a midgut [Automatically generated definition]. UBERON:0003281 mesentery of stomach biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003281 ventriculus mesentery|mesentery of ventriculus|stomach mesentery|mesogastrium|mesogaster|mesogastium The portion of the primitive mesentery that encloses the stomach; from its dorsal sheet, the greater omentum develops, and from its ventral sheet, the lesser omentum. UBERON:0003282 mesentery of heart biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003282 heart mesentery|mesocardium|cardiac mesentery A mesentery that surrounds the heart. GO:0080180 2-methylguanosine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080180 The chemical reactions and pathways involving 2-methylguanosine. GO:0080181 lateral root branching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080181 Any process involved in the formation of branches in lateral roots. CHEBI:46824 2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-olate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46824 CHEBI:46825 6-oxo-6,7-dihydro-1H-purine-2,8-diolate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46825 CHEBI:46826 2,6,8-trioxo-3,6,8,9-tetrahydro-2H-purine-1,7-diide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46826 CHEBI:46827 carboxypyridinecarboxylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46827 UBERON:0003289 meninx of telencephalon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003289 meninges of telencephalon|telencephalon meninx|telencephalon meninges A meninx that is part of a telencephalon [Automatically generated definition]. CHEBI:46828 quinolinate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46828 UBERON:0003288 meninx of midbrain biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003288 mesencephalon meninges|midbrain meninges|meninges of midbrain|midbrain meninx A meninx that is part of a midbrain [Automatically generated definition]. CHEBI:46811 2,6-dihydroxy-7,9-dihydro-8H-purin-8-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46811 CHEBI:46812 1,3-oxazoles biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46812 CHEBI:46814 9H-purine-2,6,8-triol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46814 CHEBI:46817 7H-purine-2,6,8-triol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46817 UBERON:0003278 skeleton of lower jaw biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003278 lower jaw|mandibles|mandible|lower jaw skeleton|mandibular series A subdivision of the skeleton that corresponds to the lower part of the mouth. The lower jaw skeleton includes the following elements, when present: lower jaw teeth, the mandible and other lower jaw bones, and Meckel's cartilage. UBERON:0003279 endothelium of trachea biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003279 trachea endothelium|endothelium of windpipe|windpipe endothelium An endothelium that is part of a trachea. CHEBI:46818 urate anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46818 CHEBI:46819 urate salt biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46819 UBERON:0003277 skeleton of upper jaw biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003277 upper jaw|upper jaw skeleton A subdivision of the skeleton that corresponds to the upper part of the mouth. The lower jaw skeleton includes the following elements, when present: upper jaw teeth, the maxilla and other lower jaw bones. CHEBI:46800 ethanethioic O-acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46800 UBERON:0003261 thyroid primordium endoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003261 endoderm of thyroid primordium An endoderm that is part of a thyroid primordium. UBERON:0003260 endoderm of hindgut biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003260 hindgut endoderm An endoderm that is part of a hindgut [Automatically generated definition]. UBERON:0003269 skeletal muscle tissue of eye biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003269 eye skeletal muscle|eye skeletal muscle group|eye skeletal muscle tissue|skeletal muscle tissue of eye A portion of skeletal muscle tissue that is part of a eye [Automatically generated definition]. UBERON:0003267 tooth of upper jaw biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003267 maxillary tooth|upper jaw tooth A calcareous tooth that is part of the upper jaw region. In mammals, the upper jaw teeth are attached to the maxilla. UBERON:0003268 tooth of lower jaw biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003268 lower jaw tooth|calcareous tooth of lower jaw|lower jaw dentine containing tooth|mandibular tooth|lower jaw calcareous tooth|lower jaw vertebrate tooth A calcareous tooth that is part of the lower jaw region. In mammals, the lower jaw teeth are attached to the mandible (dentary). UBERON:0003265 chorionic mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003265 chorion mesoderm|mesenchyme of chorion|chorionic mesenchyme|chorion mesenchyme|mesenchyme of chorion (vertebrates) A mesenchyme that is part of a chorion. CHEBI:22823 beta-alanine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22823 CHEBI:22838 beta-cyclopiazonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22838 NCBITaxon:9604 Hominidae organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_9604 Pongidae|great apes NCBITaxon:9605 Homo organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_9605 humans NCBITaxon:9606 Homo sapiens organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_9606 human|man CHEBI:22801 beta-D-glucosyl-N-acylsphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_22801 CHEBI:4828 ergothioneine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_4828 GO:0031193 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031193 GO:0031194 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031194 GO:0031191 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031191 GO:0031192 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031192 GO:0031190 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031190 GO:0031199 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031199 GO:0031197 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031197 GO:0031198 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031198 GO:0031195 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031195 GO:0031196 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031196 GO:0070790 phialide development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070790 development of secondary sterigmata The process whose specific outcome is the progression of phialides over time, from its formation to the mature structure. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip. Chains of conidia, or asexual spores, develop from the phialide tips. GO:0070791 cleistothecium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070791 The process whose specific outcome is the progression of the cleistothecium over time, from its formation to the mature structure. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella. GO:0080117 secondary growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080117 cambial secondary growth Lateral growth of a plant axis (shoot axis or root) that is an increase in thickness resulting from formation of secondary vascular tissues by the vascular cambium. GO:0080118 brassinosteroid sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080118 Catalysis of the reaction: a brassinosteroid + 3'-phosphoadenosine-5'-phosphosulfate = sulfated brassinosteroid + adenosine-3',5'-diphosphate. This reaction is the transfer of a sulfate group to the hydroxyl group of a brassinosteroid acceptor, producing the sulfated brassinosteroid derivative. GO:0080119 ER body organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080119 ER body organization and biogenesis|ER body organisation|endoplasmic reticulum body organization and biogenesis|endoplasmic reticulum body organization A process that is carried out at the cellular level which results in the formation of ER (endoplasmic reticulum) body. ER body is a compartment found in plant cells that is derived from the ER. The structures have a characteristic shape and size (10 mm long and 0.5 mm wide) and are surrounded with ribosomes. They have been found in Arabidopsis thaliana and related Brassicaceae species. GO:0080113 regulation of seed growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080113 regulation of seed size Any process that modulates the frequency, rate or extent of growth of the seed of an plant. GO:0080114 positive regulation of glycine hydroxymethyltransferase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080114 Any process that activates or increases the frequency, rate or extent of glycine hydroxymethyltransferase activity, the catalysis of the reaction 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine. GO:0080115 myosin XI tail binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080115 Interacting selectively and non-covalently with the tail region of a myosin XI heavy chain. GO:0080116 glucuronoxylan glucuronosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080116 Catalysis of the transfer of glucuronate to the xylan backbone of glucuronoxylan molecule. GO:0080110 sporopollenin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080110 sporopollenin biosynthesis The chemical reactions and pathways resulting in the formation of sporopollenin, a primary constituent of the pollen exine layer. GO:0080111 DNA demethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080111 The removal of a methyl group from one or more nucleotides within an DNA molecule. GO:0080112 seed growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080112 The increase in size or mass of a seed. A seed is a propagating organ formed in the reproductive cycle of a spermatophyte, derived from the ovule and enclosing an embryo. GO:0021828 gonadotrophin-releasing hormone neuronal migration to the hypothalamus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021828 gonadotropin-releasing hormone neuronal migration to the hypothalamus The directional movement of a gonadotrophin-releasing hormone producing neuron from the nasal placode to the hypothalamus. GO:0021829 oligodendrocyte cell migration from the subpallium to the cortex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021829 The directed movement of oligodendrocytes from the subpallium to the cerebral cortex during forebrain development. UBERON:0003216 hard palate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003216 palatum durum|hard palate Anterior portion of the palate consisting of bone and mucous membranes[GO]. The hard palate is formed from bony processes of the maxilla, premaxilla and palatine[Kardong]. GO:0070798 positive regulation of cleistothecium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070798 Any process that activates or increases the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella. GO:0021820 extracellular matrix organization in marginal zone involved in cerebral cortex radial glia guided migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021820 organization of extracellular matrix in the marginal zone involved in cerebral cortex glial-mediated radial migration|extracellular matrix organisation in marginal zone involved in cerebral cortex radial glia guided migration The process that leads to the deposition of extracellular matrix signals in the marginal zone of the developing cerebral cortex. This extracellular matrix controls the movement of migrating cells. In mammals, the matrix is modified by Cajal-Retzius cells. GO:0021821 negative regulation of cell-glial cell adhesion involved in cerebral cortex lamination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021821 inhibition of cell-glial cell adhesion involved in cerebral cortex lamination|down regulation of cell-glial cell adhesion involved in cerebral cortex lamination|downregulation of cell-glial cell adhesion involved in cerebral cortex lamination|down-regulation of cell-glial cell adhesion involved in cerebral cortex lamination The process that results in the release of migrating cells from their interaction with radial glial cells as a component of the process of cerebral cortex glial-mediated radial cell migration. GO:0070799 regulation of conidiophore stalk development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070799 Any process that modulates the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop. UBERON:0003214 mammary gland alveolus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003214 alveolus of mammary gland|lactiferous gland alveolus|mammary alveoli|mammary alveolus|lobe of mammary gland alveolus|alveolus of lobe of breast|lobe of breast alveolus|alveolus of lobe of mammary gland|lactiferous alveolus|alveolus of lactiferous gland A sac-like structure that is found in the mature gland[GO]. GO:0021822 negative regulation of cell motility involved in cerebral cortex radial glia guided migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021822 down-regulation of cell locomotion involved in cerebral cortex glial-mediated radial cell migration|negative regulation of cell locomotion involved in cerebral cortex radial glia guided migration|negative regulation of cell locomotion involved in cerebral cortex glial-mediated radial migration|downregulation of cell locomotion involved in cerebral cortex glial-mediated radial cell migration|down regulation of cell locomotion involved in cerebral cortex glial-mediated radial cell migration|inhibition of cell locomotion involved in cerebral cortex glial-mediated radial cell migration The intracellular signaling pathway that results in the cessation of cell movement involved in lamination of the cerebral cortex. GO:0070796 regulation of cleistothecium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070796 Any process that modulates the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella. GO:0021823 cerebral cortex tangential migration using cell-cell interactions biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021823 chain migration The process in which neurons interact with each other to promote migration along a tangential plane. UBERON:0003215 alveolus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003215 organ part that has the form of a hollow cavity[WP]. GO:0070797 negative regulation of cleistothecium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070797 Any process that stops, prevents, or reduces the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella. UBERON:0003212 gustatory organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003212 taste organ|organ of gustatory organ system|gustatory organ system organ|organ of gustatory system|organ of taste system|gustatory system organ|taste system organ Any sense organ that functions in (some) detection of chemical stimulus involved in sensory perception of taste (GO:0050912). GO:0070794 negative regulation of conidiophore development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070794 Any process that stops, prevents, or reduces the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores. GO:0021824 cerebral cortex tangential migration using cell-axon interactions biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021824 The movement of cerebral cortex neuronal precursors tangentially through the cortex using interaction of the migrating cells with axons of other neurons. GO:0021825 substrate-dependent cerebral cortex tangential migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021825 The process where neuronal precursors migrate tangentially in the cerebral cortex, primarily guided through physical cell-cell interactions. GO:0070795 positive regulation of conidiophore development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070795 Any process that activates or increases the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores. UBERON:0003210 blood-cerebrospinal fluid barrier biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003210 blood-CSF barrier barrier in the choroid plexus located in the lateral, third, and fourth brain ventricles that controls the entrance of substances into the cerebrospinal fluid from the blood[MP]. GO:0021826 substrate-independent telencephalic tangential migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021826 The process where neuronal precursors migrate tangentially in the telencephalon, primarily guided by interactions that do not require cell-cell contact. GO:0070792 Hulle cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070792 Huelle cell development|Hulle cell formation The process whose specific outcome is the progression of Hulle cells over time, from their formation to the mature structures. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body. GO:0070793 regulation of conidiophore development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070793 Any process that modulates the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores. GO:0021827 postnatal olfactory bulb interneuron migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021827 The migration of olfactory bulb interneuron precursors in the cerebral cortex that occurs after birth. GO:0070780 dihydrosphingosine-1-phosphate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070780 MetaCyc:RXN3DJ-25|RHEA:27514|Reactome:R-HSA-428664 sphinganine-1-phosphate phosphatase activity|dihydrosphingosine-1-phosphate phosphohydrolase activity Catalysis of the reaction: dihydrosphingosine 1-phosphate + H2O = dihydrosphingosine + phosphate. GO:0080106 7-methylthiopropyl glucosinolate S-oxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080106 Catalysis of the reaction: 7-methylthiopropyl-glucosinolate = 7-methylsulfinylpropyl-glucosinolate. GO:0080107 8-methylthiopropyl glucosinolate S-oxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080107 Catalysis of the reaction: 8-methylthiopropyl-glucosinolate = 8-methylsulfinylpropyl-glucosinolate. GO:0080108 S-alkylthiohydroximate lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080108 S-alkylthiohydroximate C-S lyase activity Catalysis of the conversion of a S-alkylthiohydroximate to a thiohydroximate. GO:0080109 indole-3-acetonitrile nitrile hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080109 KEGG_REACTION:R04020|MetaCyc:RXN-7567|EC:4.2.1.84 Catalysis of the reaction: indole-3-acetonitrile + H2O = indole-3-acetamide. GO:0080102 3-methylthiopropyl glucosinolate S-oxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080102 MetaCyc:RXN-2221 Catalysis of the reaction: 3-methylthiopropyl-glucosinolate = 3-methylsulfinylpropyl-glucosinolate. GO:0080103 4-methylthiopropyl glucosinolate S-oxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080103 Catalysis of the reaction: 4-methylthiopropyl-glucosinolate = 4-methylsulfinylpropyl-glucosinolate. GO:0080104 5-methylthiopropyl glucosinolate S-oxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080104 Catalysis of the reaction: 5-methylthiopropyl-glucosinolate = 5-methylsulfinylpropyl-glucosinolate. GO:0080105 6-methylthiopropyl glucosinolate S-oxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080105 Catalysis of the reaction: 6-methylthiopropyl-glucosinolate = 6-methylsulfinylpropyl-glucosinolate. GO:0080100 L-glutamine:2-oxoglutarate aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080100 EC:2.6.1.50 L-glutamine:alpha-ketoglutarate aminotransferase activity Catalysis of the reaction: L-glutamine + 2-oxoglutarate = 2-oxoglutaramate + L-glutamate. GO:0080101 phosphatidyl-N-dimethylethanolamine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080101 RHEA:32739|MetaCyc:RXN4FS-2|EC:2.1.1.71|KEGG_REACTION:R01320 Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidyl-N-dimethylethanolamine = S-adenosyl-L-homocysteine + phosphatidylcholine. GO:0021817 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021817 nucleokinesis involved in cell locomotion in cerebral cortex glial-mediated radial migration|nucleokinesis involved in cell locomotion in cerebral cortex radial glia guided migration The microtubule-mediated movement of the nucleus that is required for the movement of cells along radial glial fibers as a component of the process of cerebral cortex glial-mediated radial cell migration. CHEBI:32274 UDP-3-keto-alpha-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32274 GO:0021818 modulation of the microfilament cytoskeleton involved in cell locomotion in cerebral cortex radial glia guided migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021818 modulation of the microfilament cytoskeleton involved in cell locomotion in cerebral cortex glial-mediated radial migration The changes in the actin cytoskeleton that are necessary for the movement of cells along radial glial cells as a component of the process of cerebral cortex glial-mediated radial cell migration. CHEBI:32275 UDP-alpha-D-kanosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32275 GO:0021819 layer formation in cerebral cortex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021819 cerebral cortex lamination The detachment of cells from radial glial fibers at the appropriate time when they cease to migrate and form distinct layer in the cerebral cortex. CHEBI:4885 ethionamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_4885 GO:0070789 metula development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070789 development of primary sterigmata The process whose specific outcome is the progression of metulae over time, from its formation to the mature structure. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip. GO:0070787 conidiophore development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070787 The process whose specific outcome is the progression of the conidiophore over time, from its formation to the mature structure. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores. GO:0021810 neurotransmitter signaling initiating cell movement, involved in cerebral cortex radial glia guided migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021810 neurotransmitter signalling initiating cell movement, involved in cerebral cortex glial-mediated radial migration Signaling by neurotransmitters and their receptors that results in the initiation of movement of cells as a component of the process of glial-mediated radial migration. GO:0070788 conidiophore stalk development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070788 The process whose specific outcome is the progression of the conidiophore stalk over time, from its formation to the mature structure. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop. GO:0070785 negative regulation of growth of unicellular organism as a thread of attached cells biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070785 Any process that decreases the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium. GO:0021811 growth factor signaling initiating cell movement involved in cerebral cortex radial glia guided migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021811 growth factor signalling initiating cell movement involved in cerebral cortex glial-mediated radial migration|growth factor signaling initiating cell movement involved in cerebral cortex glial-mediated radial migration Signaling between growth factors and their receptors that results in the start of cell movement, where this process is involved in glial-mediated radial migration in the cerebral cortex. GO:0070786 positive regulation of growth of unicellular organism as a thread of attached cells biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070786 Any process that activates or increases the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium. GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021812 neuronal-glial interaction involved in cerebral cortex glial-mediated radial migration The changes in adhesion between neuronal cells and glial cells as a component of the process of cerebral cortex glial-mediated radial cell migration. GO:0021813 cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021813 cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex glial-mediated radial migration The interaction between two cells that modulates the association of a neuronal cell and a glial cell involved in glial-mediated radial cell migration in the cerebral cortex. GO:0070783 growth of unicellular organism as a thread of attached cells biolink:BiologicalProcess go-plus goslim_candida http://purl.obolibrary.org/obo/GO_0070783 A filamentous growth process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium such as an agar plate, exhibited by unicellular fungi under certain growth conditions. GO:0070784 regulation of growth of unicellular organism as a thread of attached cells biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070784 Any process that modulates the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium. GO:0021814 cell motility involved in cerebral cortex radial glia guided migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021814 cell locomotion involved in cerebral cortex radial glia guided migration|cell locomotion involved in cerebral cortex glial-mediated radial migration The movement of a cell along the process of a radial glial cell involved in cerebral cortex glial-mediated radial migration. GO:0070781 response to biotin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070781 response to vitamin H|response to Bios IIB|response to vitamin B7|response to coenzyme R Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotin stimulus. GO:0021815 modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021815 modulation of microtubule cytoskeleton involved in cerebral cortex glial-mediated radial migration Rearrangements of the microtubule cytoskeleton that contribute to the movement of cells along radial glial cells as a component of the process of cerebral cortex glial-mediated radial migration. GO:0070782 phosphatidylserine exposure on apoptotic cell surface biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070782 externalization of phosphatidylserine A phospholipid scrambling process that results in the appearance of phosphatidylserine on the outer leaflet of the plasma membrane of an apoptotic cell, which acts as an 'eat-me' signal for engulfing cells. Phosphatidylserine is exposed on the apoptotic cell surface by a phospholipid scramblase activity. GO:0021816 extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021816 The rearrangements of the microtubule cytoskeleton that result in the extension of a leading process, where this process is involved in the movement of cells along radial glial cells. CHEBI:46895 lipopeptide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46895 CHEBI:46896 diacyl lipopeptide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46896 GO:0080139 borate efflux transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080139 boron efflux transmembrane transporter activity Enables the transfer of borate from the inside of the cell to the outside of the cell across a membrane. CHEBI:46898 cholesteryl oleate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46898 GO:0080135 regulation of cellular response to stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080135 Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular response to stress is a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). GO:0080136 priming of cellular response to stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080136 priming of stress response|priming of response to stress The process that enables cells to respond in a more rapid and robust manner than nonprimed cells to much lower levels of a stimulus indicating the organism is under stress. GO:0080137 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0080137 GO:0080138 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0080138 GO:0080131 hydroxyjasmonate sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080131 OHJA sulfotransferase activity|12-hydroxyjasmonic acid sulfotransferase activity|11-hydroxyjasmonic acid sulfotransferase activity|hydroxyjasmonic acid sulfotransferase activity|12-hydroxyjasmonate sulfotransferase activity|12-OHJA sulfotransferase activity|11-hydroxyjasmonate sulfotransferase activity|11-OHJA sulfotransferase activity Catalysis of the reaction: a hydroxyjasmonate + 3'-phosphoadenosine-5'-phosphosulfate = a hydroxyjasmonate sulfate + adenosine-3',5'-diphosphate. GO:0080132 fatty acid alpha-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080132 Reactome:R-HSA-5693761 fatty acid 2-hydroxylase Catalysis of the conversion of a fatty acid to an alpha-hydroxylated fatty acid. A hydroxyl group is added to the second carbon, counted from the carboxyl end, of a fatty acid chain. CHEBI:46890 silicon hydroxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46890 UBERON_CORE:trunk_part_of trunk_part_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/uberon/core#trunk_part_of trunk_part_of GO:0080133 midchain alkane hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080133 Catalysis of the conversion of an alkane to a secondary alcohol. CHEBI:46891 azetidinecarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46891 GO:0080134 regulation of response to stress biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0080134 Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). GO:0021806 initiation of movement involved in cerebral cortex radial glia guided migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021806 initiation of movement involved in cerebral cortex glial-mediated radial migration The initial stages of cell motility involved in the glial-mediated movement of cells in the developing cerebral cortex. GO:0021807 motogenic signaling initiating cell movement in cerebral cortex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021807 motogenic signalling initiating cell movement in the cerebral cortex The interaction of soluble factors and receptors that result in the movement of cells in the primitive cerebral cortex. GO:0021808 cytosolic calcium signaling involved in initiation of cell movement in glial-mediated radial cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021808 cytosolic calcium signalling involved in the initiation of cell movement in glial-mediated radial cell migration The process that results in the fluctuations in intracellular calcium that are responsible for the initiation of movement as a component of the process of cerebral cortex glial-mediated radial migration. GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080130 KEGG_REACTION:R00694|MetaCyc:RXN-10814|RHEA:25152|MetaCyc:PHEAMINOTRANS-RXN|EC:2.6.1.57 L-phenylalanine:alpha-ketoglutarate aminotransferase activity Catalysis of the reaction: L-phenylalanine + 2-oxoglutarate = phenylpyruvate + L-glutamate. GO:0021809 neurotrophic factor signaling initiating cell movement, involved in cerebral cortex radial glia guided migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021809 neurotrophic factor signalling initiating cell movement, involved in cerebral cortex glial-mediated radial migration Signaling between members of the neurotrophin family and their receptors that result in the start of cell motility as a component of the process of cerebral cortex glial-mediated radial migration. GO:0021800 cerebral cortex tangential migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021800 The migration of cells in the cerebral cortex in which cells move orthogonally to the direction of radial migration and do not use radial glial cell processes as substrates for migration. GO:0021801 cerebral cortex radial glia guided migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021801 glial-guided locomotion The radial migration of neuronal or glial precursor cells along radial glial cells during the development of the cerebral cortex. GO:0021802 somal translocation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021802 perikaryal translocation of Morest The radial migration of cells from the ventricular zone that is independent of radial glial cells. Cells extend processes that terminate at the pial surface and follow the processes as they migrate. GO:0021803 extension of leading cell process to pial surface biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021803 The extension of a long process to the pial surface as a cell leaves the ventricular zone. GO:0021804 negative regulation of cell adhesion in ventricular zone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021804 inhibition of cell adhesion in ventricular zone|down regulation of cell adhesion in ventricular zone|downregulation of cell adhesion in ventricular zone|down-regulation of cell adhesion in ventricular zone The process that results in the loss of attachments of a cell in the ventricular zone. GO:0021805 cell movement involved in somal translocation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021805 cell motility involved in somal translocation The movement of a cell body from the ventricular zone to the pial surface with a concomitant shortening of the process that extends to the pial surface. CHEBI:46883 carboxy group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46883 GO:0080128 anther septum development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080128 The process whose specific outcome is the progression of the anther septum over time, from its formation to the mature structure. The anther septum is a thin partition or stretch of cells that are present in the anther dehiscence zone. GO:0080129 proteasome core complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080129 20S proteasome assembly The aggregation, arrangement and bonding together of a mature, active 20S proteasome core particle complex that does not contain any regulatory particles. GO:0080124 pheophytinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080124 pheophytin pheophorbide hydrolase activity Catalysis of the reaction: pheophytin + H2O = phytol + pheophorbide. GO:0080125 obsolete multicellular structure septum development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080125 OBSOLETE. The process whose specific outcome is the progression of the multicellular structure septum over time, from its formation to the mature structure. The multicellular structure septum is the thin partition or membrane that divides a cavity or a mass of tissue. GO:0080126 ovary septum development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080126 The process whose specific outcome is the progression of the ovary septum over time, from its formation to the mature structure. The ovary septum is the thin partition that divides the ovary, the basal portion of a carpel or group of fused carpels, that encloses the ovule(s). GO:0080127 fruit septum development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080127 The process whose specific outcome is the progression of the fruit septum over time, from its formation to the mature structure. The fruit septum is a thin partition or membrane that divides a cavity or a mass of tissue in the fruit. GO:0080120 CAAX-box protein maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080120 farnesylated protein maturation|CAAX-box protein processing A series of specific posttranslational modifications to the CAAX box region of CAAX box proteins. CAAX box proteins are eukaryotic proteins that contain a CAAX motif where the C is a cysteine, the two A residues are aliphatic amino acids and the X can be one of several amino acids. The CAAX-box proteins undergo three sequential, enzymatic, post-translational modifications essential to their targeting: First, the proteins are prenylated by one of two prenyltransferases called farnesyltransferase and geranylgeranyltransferase-I. Prenylation results in the covalent attachment of either farnesyl or geranylgeranyl isoprenoid groups to the cysteine in the CAAX box motif. Prenylation is followed by proteolytic removal of the last three amino acids of the protein (AAX). Finally, the newly exposed carboxylate group of the isoprenylcysteine is methylated by an ER-associated prenyl-dependent carboxylmethyltransferase. GO:0080121 AMP transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080121 adenosine monophosphate transport The directed movement of AMP, adenosine monophosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0080122 AMP transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080122 adenosine monophosphate transmembrane transporter activity Enables the transfer of AMP, adenosine monophosphate, from one side of a membrane to the other. GO:0080123 jasmonate-amino synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080123 jasmonate:amino acid synthetase activity|jasmonyl-amino synthetase activity|jasmonate-amino acid synthetase activity|ja-amino synthetase activity|jasmonic acid-amino synthetase activity|jasmonate-amino acid conjugate synthetase activity|jasmonate-amido synthetase activity Catalysis of the reaction: jasmonate + an amino acid = an amide-linked jasmonyl-amino acid conjugate. The substrates of this reaction include non-standard amino acids, such as ACC (1-aminocyclopropane-1-carboxylate). CHEBI:4866 17beta-estradiol 3-sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_4866 CHEBI:46874 alpha-amino acid ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46874 GO:0080157 regulation of plant-type cell wall organization or biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080157 regulation of plant-type cell wall organisation or biogenesis Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving plant-type cell wall organization or biogenesis. Plant-type cell wall organization or biogenesis is a process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellulose- and pectin-containing cell wall. GO:0080158 obsolete chloroplast ribulose bisphosphate carboxylase complex biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080158 OBSOLETE. A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a chloroplast ribulose bisphosphate carboxylase (RubisCO) complex. Includes the synthesis of the constituent protein molecules, and those protein modifications that are involved in synthesis or assembly of the complex. GO:0080159 zygote elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080159 The process in which the zygote irreversibly increases in size in one dimension after fertilization. An example of such a process is found in Arabidopsis thaliana. GO:0080153 negative regulation of reductive pentose-phosphate cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080153 negative regulation of C3 photosynthesis|negative regulation of Calvin cycle Any process that stops, prevents, or reduces the frequency, rate or extent of the reductive pentose-phosphate cycle. GO:0080154 regulation of fertilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080154 Any process that modulates the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy). GO:0080155 regulation of double fertilization forming a zygote and endosperm biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080155 Any process that modulates the rate, frequency or extent of double fertilization forming a zygote and endosperm. Double fertilization forming a zygote and endosperm is a type of fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the two polar nuclei to form the 3n primary endosperm nucleus and then develops into the endosperm. The ploidy level of the 2n zygote and 3n primary endosperm nucleus is determined by the ploidy level of the parents involved. An example of this component is found in Arabidopsis thaliana. GO:0080156 mitochondrial mRNA modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080156 mitochondrial mRNA editing|mitochondrial RNA editing The covalent alteration within the mitochondrion of one or more nucleotides within an mRNA to produce an mRNA molecule with a sequence that differs from that coded genetically. UBERON:0003252 thoracic rib cage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003252 rib cage|cavea thoracis|cavea thoracis|thoracic cage Subdivision of skeletal system that consists of all ribs in an organism connected to the sternum and the vertebrae. Some vertebrates have abdominal ribs (gastrialia), not connected to the vertebrate - these are not considered part of the rib case. UBERON:0003253 neck of rib biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003253 rib neck|collum costae|collum costae The neck of the rib is the flattened portion which extends lateralward from the head; it is about 2.5 cm. long, and is placed in front of the transverse process of the lower of the two vertebrC& with which the head articulates. Its anterior surface is flat and smooth, its posterior rough for the attachment of the ligament of the neck, and perforated by numerous foramina. Of its two borders the superior presents a rough crest (crista colli costE) for the attachment of the anterior costotransverse ligament; its inferior border is rounded. On the posterior surface at the junction of the neck and body, and nearer the lower than the upper border, is an eminencebthe tubercle; it consists of an articular and a non-articular portion. The articular portion, the lower and more medial of the two, presents a small, oval surface for articulation with the end of the transverse process of the lower of the two vertebrC& to which the head is connected. The non-articular portion is a rough elevation, and affords attachment to the ligament of the tubercle. The tubercle is much more prominent in the upper than in the lower ribs. GO:0080150 S-adenosyl-L-methionine:benzoic acid carboxyl methyl transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080150 RHEA:36099|MetaCyc:RXN-6722 S-adenosyl-L-methionine:benzoate carboxyl methyltransferase activity Catalysis of the reaction: benzoate + S-adenosyl-L-methionine = methylbenzoate + S-adenosyl-L-homocysteine. GO:0080151 positive regulation of salicylic acid mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080151 positive regulation of salicylic acid mediated signalling pathway Any process that activates or increases the frequency, rate or extent of salicylic acid mediated signal transduction. GO:0080152 regulation of reductive pentose-phosphate cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080152 regulation of Calvin cycle|regulation of C3 photosynthesis Any process that modulates the frequency, rate or extent of reductive pentose-phosphate cycle. UBERON:0003258 endoderm of foregut biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003258 foregut endoderm An endoderm that is part of a foregut [Automatically generated definition]. UBERON:0003259 endoderm of midgut biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003259 midgut endoderm An endoderm that is part of a midgut [Automatically generated definition]. UBERON:0003257 yolk sac endoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003257 The portion of the yolk sac that is derived from endoderm and lines the yolk sac. CHEBI:46860 cinchomeronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46860 CHEBI:46861 cinchomeronate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46861 CHEBI:46862 cinchomeronate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46862 CHEBI:46863 4-carboxypyridine-3-carboxylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46863 CHEBI:46864 3-carboxypyridine-4-carboxylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46864 CHEBI:46867 indolyl carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46867 GO:0080146 L-cysteine desulfhydrase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080146 MetaCyc:LCYSDESULF-RXN|RHEA:24931|EC:4.4.1.1|Reactome:R-HSA-1614591|Reactome:R-HSA-1614614 Catalysis of the reaction: L-cysteine + H2O = ammonia + pyruvate + hydrogen sulfide + H+. GO:0080147 root hair cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080147 The process whose specific outcome is the progression of a root hair cell over time, from its formation to the mature state. GO:0080148 negative regulation of response to water deprivation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080148 Any process that stops, prevents, or reduces the frequency, rate or extent of a response to water deprivation. Response to water deprivation is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water. GO:0080149 sucrose induced translational repression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080149 negative regulation of translation in response to sucrose Any process that stops, prevents or reduces the rate of translation as a result of increase in sucrose level. GO:0080142 regulation of salicylic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080142 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of salicylic acid. GO:0080143 regulation of amino acid export biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080143 Any process that modulates the frequency, rate or extent of amino acid export. Amino acid export is the directed movement of amino acids out of a cell or organelle. GO:0080144 amino acid homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080144 Any process involved in the maintenance of an internal steady state of amino acid within an organism or cell. GO:0080145 cysteine homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080145 Any process involved in the maintenance of an internal steady state of cysteine within an organism or cell. GO:0080140 regulation of jasmonic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080140 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving jasmonic acid. GO:0080141 regulation of jasmonic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080141 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of jasmonic acid. UBERON:0003240 epithelium of lateral semicircular canal biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003240 epithelial tissue of lateral semicircular canal|lateral semicircular canal epithelial tissue|lateral semicircular canal epithelium An epithelium that is part of a lateral semicircular canal [Automatically generated definition]. UBERON:0003249 epithelium of otic placode biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003249 otic epithelium|epithelial tissue of otic placode|otic placode epithelial tissue|otic placode epithelium An epithelium that is part of a otic placode [Automatically generated definition]. UBERON:0003247 epithelium of forearm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003247 forearm epithelium An epithelium that is part of a lower arm [Automatically generated definition]. UBERON:0003248 epithelium of footplate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003248 foot plate epithelium|footplate epithelium An epithelium that is part of a footplate. UBERON:0003244 epithelium of mammary gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003244 mammary gland epithelial tissue|mammary gland epithelium|epithelium of lactiferous gland|lactiferous gland epithelium|mammary epithelium the epithelial layer of the luminal surfaces of the mammary gland CHEBI:46850 organoammonium salt biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46850 CHEBI:46851 N-(2-hydroxyethyl)piperazine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46851 CHEBI:22881 biopterins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22881 CHEBI:46853 piperazinecarboxamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46853 CHEBI:46854 L-glutamo group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46854 UBERON:0003229 epithelium of elbow biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003229 cubital region epithelial tissue|epithelial tissue of elbow|elbow epithelial tissue|elbow epithelium|epithelial tissue of cubital region|epithelium of cubital region|cubital region epithelium An epithelium that is part of a elbow [Automatically generated definition]. CHEBI:46855 L-alpha-glutamyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46855 CHEBI:46856 11-cis-retinoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46856 GO:0080179 1-methylguanosine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080179 The chemical reactions and pathways involving 1-methylguanosine. CHEBI:32205 tetracenomycin F1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32205 CHEBI:32207 tetracenomycin F2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32207 GO:0080175 phragmoplast microtubule organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080175 phragmoplast microtubule organisation|phragmoplast microtubule cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in phragmoplast, a plant cell specific structure that forms during late cytokinesis. Phragmoplast serves as a scaffold for cell plate assembly and subsequent formation of a new cell wall separating the two daughter cells. GO:0080176 xyloglucan 1,6-alpha-xylosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080176 Catalysis of the hydrolysis of xyloglucan side chains so as to remove unsubstituted D-xylose residues attached to the glucose located at the non-reducing terminus. GO:0080177 plastoglobule organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080177 plastoglobule organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plastoglobule. Plastoglobule is a lipoprotein particle present in chloroplasts. They are rich in non-polar lipids (triglycerides, esters) as well as in prenylquinones, plastoquinone and tocopherols. Plastoglobules are often associated with thylakoid membranes, suggesting an exchange of lipids with thylakoids. GO:0080178 5-carbamoylmethyl uridine residue modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080178 5-carbamoylmethyluridine metabolic process The chemical reactions and pathways involving the addition of a 5-carbamoylmethyl group to a uridine residue in RNA. GO:0080171 lytic vacuole organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080171 lytic vacuolar assembly|lytic vacuole organization and biogenesis|lytic vacuole biogenesis|lytic vacuole organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lytic vacuole. UBERON:0003230 epithelium of carpal region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003230 epithelium of wrist|epithelial tissue of wrist|carpal region epithelium|epithelial tissue of carpal region|wrist epithelial tissue|wrist epithelium|carpal region epithelial tissue An epithelium that is part of a wrist [Automatically generated definition]. UBERON:0003231 epithelium of hip biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003231 hip region epithelium|regio coxae epithelium|epithelial tissue of hip|epithelium of regio coxae|hip epithelial tissue|hip epithelium|epithelial tissue of hip region|epithelial tissue of regio coxae|epithelium of hip region|regio coxae epithelial tissue|hip region epithelial tissue An epithelium that is part of a hip [Automatically generated definition]. GO:0080172 petal epidermis patterning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080172 The regionalization process that regulates the coordinated growth and establishes the non-random spatial arrangement of the cells in the petal epidermis. GO:0080173 male-female gamete recognition during double fertilization forming a zygote and endosperm biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080173 gamete recognition|male-female gamete recognition The initial contact step made between the male gamete and the female gamete during double fertilization forming a zygote and endosperm. An example can be found in Arabidopsis thaliana. GO:0080174 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0080174 CHEBI:32202 tetracenomycin D3 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32202 GO:0080170 hydrogen peroxide transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080170 hydrogen peroxide membrane transport The process in which hydrogen peroxide is transported across a membrane. UBERON:0003238 epithelium of superior semicircular canal biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003238 epithelial tissue of superior semicircular canal|superior semicircular canal epithelial tissue|epithelium of anterior semicircular canal|epithelial tissue of anterior semicircular canal|anterior semicircular canal epithelial tissue|anterior semicircular canal epithelium|superior semicircular canal epithelium An epithelium that is part of an anterior semicircular canal [Automatically generated definition]. UBERON:0003239 epithelium of posterior semicircular canal biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003239 posterior semicircular canal epithelium|epithelial tissue of posterior semicircular canal|posterior semicircular canal epithelial tissue An epithelium that is part of a posterior semicircular canal [Automatically generated definition]. CHEBI:46858 L-tyrosine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46858 UBERON:0003236 epithelium of lower jaw biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003236 epithelium of ventral mandibular arch|epithelial tissue of ventral mandibular arch|ventral mandibular arch epithelial tissue|ventral mandibular arch epithelium|epithelial tissue of lower jaw|lower jaw epithelial tissue|lower jaw epithelium An epithelium that is part of a lower jaw [Automatically generated definition]. CHEBI:22888 biphenyls biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22888 UBERON:0003235 epithelium of upper jaw biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003235 epithelium of palatoquadrate arch|epithelial tissue of palatoquadrate arch|palatoquadrate arch epithelium|palatoquadrate arch epithelial tissue|epithelial tissue of upper jaw|upper jaw epithelial tissue|upper jaw epithelium An epithelium that is part of a upper jaw [Automatically generated definition]. UBERON:0003232 epithelium of knee biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003232 epithelial tissue of knee|knee epithelial tissue|knee epithelium An epithelium that is part of a knee [Automatically generated definition]. UBERON:0003233 epithelium of shoulder biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003233 epithelial tissue of shoulder|shoulder epithelial tissue|shoulder epithelium An epithelium that is part of a shoulder [Automatically generated definition]. CHEBI:22894 bis(molybdopterin guanine dinucleotide)molybdenum biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22894 CHEBI:46842 sarcosinium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46842 UBERON:0003218 ovary septum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003218 Septum that divides the ovary, the basal portion of a carpel or group of fused carpels, that encloses the ovule(s)[GO]. CHEBI:46845 N-alkylpiperazine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46845 GO:0080168 abscisic acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080168 The directed movement of abscisic acid into, out of, within or between cells by means of some external agent such as a transporter or pore. GO:0080169 cellular response to boron-containing substance deprivation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080169 cellular response to boron deprivation|cellular response to boron starvation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of boron obtained from boron-containing substances. GO:0080164 regulation of nitric oxide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080164 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water. GO:0080165 callose deposition in phloem sieve plate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080165 Any process in which callose is transported to, and/or maintained in, phloem sieve plate. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls. GO:0080166 stomium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080166 The process whose specific outcome is the progression of the stomium over time, from its formation to the mature structure. A stomium is a fissure or pore in the anther lobe through which the pollen is released. GO:0080167 response to karrikin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080167 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a karrikin stimulus. Karrikins are signaling molecules in smoke from burning vegetation that trigger seed germination for many angiosperms (flowering plants). GO:0080160 selenate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080160 The directed movement of selenate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0080161 auxin transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0080161 Enables the transfer of auxins from one side of a membrane to the other. Auxins are plant hormones that regulate aspects of plant growth. UBERON:0003220 metanephric mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003220 metanephrogenic mesenchyme|metanephric blastema|metanephros associated mesenchyme|metanephric mesoderm one of the two embryological structures that give rise to the kidney (the other is the ureteric bud). The metanephric blastema mostly develops into nephrons, but can also form parts of the collecting duct system.[WP]. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros[GO] GO:0080162 intracellular auxin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080162 The directed movement of auxins within a cell. Auxins are a group of plant hormones that regulates aspects of plant growth. GO:0080163 regulation of protein serine/threonine phosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0080163 regulation of protein phosphatase type 2c activity Any process that modulates the frequency, rate or extent of protein serine/threonine phosphatase activity: catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate. CHEBI:46846 piperazinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46846 CHEBI:46847 N-iminopiperazine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46847 CHEBI:46848 N-arylpiperazine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46848 CHEBI:22899 bisdechlorogeodin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_22899 UBERON:0003221 phalanx biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003221 digit long bone|phalange|phalanges|long bone of digit|phalanx bone Endochondral bones that are often elongate and arranged in rows of articulating elements, and form the visible part of the digits. GO:0031348 negative regulation of defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031348 down-regulation of defense response|downregulation of defense response|down regulation of defense response|inhibition of defense response Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response. GO:0031349 positive regulation of defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031349 stimulation of defense response|up-regulation of defense response|activation of defense response|up regulation of defense response|upregulation of defense response Any process that activates or increases the frequency, rate or extent of a defense response. GO:0031346 positive regulation of cell projection organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031346 positive regulation of cell projection organisation|positive regulation of cell projection organization and biogenesis|up regulation of cell projection organization|upregulation of cell projection organization|stimulation of cell projection organization|up-regulation of cell projection organization|activation of cell projection organization Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections. GO:0031347 regulation of defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031347 Any process that modulates the frequency, rate or extent of a defense response. GO:0045996 negative regulation of transcription by pheromones biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045996 inhibition of transcription by pheromones|down regulation of transcription by pheromones|downregulation of transcription by pheromones|down-regulation of transcription by pheromones Any process involving pheromones that stops, prevents or reduces the rate of transcription. GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006388 tRNA-Y splicing Splicing of tRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons. GO:0006389 obsolete tRNA-Y splicing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006389 tRNA-Y splicing OBSOLETE. (Was not defined before being made obsolete). GO:0045997 negative regulation of ecdysteroid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045997 negative regulation of ecdysteroid anabolism|down-regulation of ecdysteroid biosynthetic process|negative regulation of ecdysteroid biosynthesis|negative regulation of ecdysteroid synthesis|negative regulation of ecdysteroid formation|downregulation of ecdysteroid biosynthetic process|down regulation of ecdysteroid biosynthetic process|inhibition of ecdysteroid biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ecdysteroids. GO:0006386 termination of RNA polymerase III transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006386 transcription termination from RNA polymerase III promoter|RNA polymerase III transcription termination factor activity|transcription termination from Pol III promoter|RNA polymerase III transcription termination The process in which transcription by RNA polymerase III is terminated; Pol III has an intrinsic ability to terminate transcription upon incorporation of 4 to 6 contiguous U residues. GO:0045994 positive regulation of translational initiation by iron biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045994 upregulation of translational initiation by iron|stimulation of translational initiation by iron|activation of translational initiation by iron|up-regulation of translational initiation by iron|up regulation of translational initiation by iron Any process involving iron that activates or increases the rate of translational initiation. GO:0045995 regulation of embryonic development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045995 Any process that modulates the frequency, rate or extent of embryonic development. GO:0006387 obsolete snRNA capping biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006387 snRNA capping OBSOLETE. The sequence of enzymatic reactions resulting in the addition of a cap to the 5' end of a nascent snRNA transcript. GO:0006384 transcription initiation from RNA polymerase III promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006384 transcription initiation from Pol III promoter|transcription initiation from RNA polymerase III type 1 promoter|transcription initiation from RNA polymerase III type 2 promoter|transcription initiation from RNA polymerase III type 3 promoter|transcription initiation from RNA polymerase III hybrid type promoter Any process involved in the assembly of the RNA polymerase III preinitiation complex (PIC) at an RNA polymerase III promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription. GO:0045992 negative regulation of embryonic development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045992 down regulation of embryonic development|downregulation of embryonic development|down-regulation of embryonic development|inhibition of embryonic development Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development. GO:0045993 negative regulation of translational initiation by iron biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045993 down regulation of translational initiation by iron|inhibition of translational initiation by iron|down-regulation of translational initiation by iron|downregulation of translational initiation by iron Any process involving iron that stops, prevents or reduces the rate of translational initiation. GO:0006385 transcription elongation from RNA polymerase III promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006385 RNA polymerase III transcription elongation factor activity|RNA elongation from Pol III promoter The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase III promoter by the addition of ribonucleotides catalyzed by RNA polymerase III. GO:0006382 adenosine to inosine editing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006382 The conversion of an adenosine residue to inosine in an RNA molecule by deamination. GO:0045990 carbon catabolite regulation of transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045990 regulation of transcription by carbon catabolites A transcription regulation process in which the presence of one carbon source leads to the modulation of the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. GO:0006383 transcription by RNA polymerase III biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0006383 transcription from RNA polymerase III type 3 promoter|RNA polymerase III transcription factor activity|transcription from a RNA polymerase III hybrid type promoter|U2 snRNA transcription (S. cerevisiae)|transcription from Pol III promoter|transcription from RNA polymerase III promoter|U6 snRNA transcription (mammalian)|transcription from RNA polymerase III type 2 promoter The synthesis of RNA from a DNA template by RNA polymerase III, originating at an RNAP III promoter. GO:0045991 carbon catabolite activation of transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045991 positive regulation of transcription by carbon catabolites A transcription regulation process in which the presence of one carbon source leads to an increase in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. GO:0006391 transcription initiation from mitochondrial promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006391 A transcription initiation process that takes place at a promoter on the mitochondrial chromosome, and results in RNA synthesis by a mitochondrial RNA polymerase. GO:0006392 transcription elongation from mitochondrial promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006392 RNA elongation from mitochondrial promoter The extension of an RNA molecule after transcription initiation and promoter clearance at mitochondrial promoter by the addition of ribonucleotides catalyzed by a mitchondrial RNA polymerase. GO:0070958 negative regulation of neutrophil mediated killing of gram-positive bacterium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070958 down regulation of neutrophil mediated killing of gram-positive bacterium|inhibition of neutrophil mediated killing of gram-positive bacterium|down-regulation of neutrophil mediated killing of gram-positive bacterium|downregulation of neutrophil mediated killing of gram-positive bacterium Any process that decreases the frequency, rate or extent of the directed killing of a gram-positive bacterium by a neutrophil. GO:0070959 negative regulation of neutrophil mediated killing of fungus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070959 down-regulation of neutrophil mediated killing of fungus|inhibition of neutrophil mediated killing of fungus|down regulation of neutrophil mediated killing of fungus|downregulation of neutrophil mediated killing of fungus Any process that decreases the frequency, rate or extent of the directed killing of a fungal cell by a neutrophil. GO:0006390 mitochondrial transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006390 transcription from mitochondrial promoter The synthesis of RNA from a mitochondrial DNA template, usually by a specific mitochondrial RNA polymerase. GO:0070956 negative regulation of neutrophil mediated killing of bacterium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070956 down-regulation of neutrophil mediated killing of bacterium|downregulation of neutrophil mediated killing of bacterium|down regulation of neutrophil mediated killing of bacterium|inhibition of neutrophil mediated killing of bacterium Any process that decreases the frequency, rate or extent of the directed killing of a bacterium by a neutrophil. GO:0070957 negative regulation of neutrophil mediated killing of gram-negative bacterium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070957 downregulation of neutrophil mediated killing of gram-negative bacterium|down regulation of neutrophil mediated killing of gram-negative bacterium|inhibition of neutrophil mediated killing of gram-negative bacterium|down-regulation of neutrophil mediated killing of gram-negative bacterium Any process that decreases the frequency, rate or extent of the directed killing of a gram-negative bacterium by a neutrophil. GO:0045998 positive regulation of ecdysteroid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045998 activation of ecdysteroid biosynthetic process|up-regulation of ecdysteroid biosynthetic process|positive regulation of ecdysteroid anabolism|positive regulation of ecdysteroid synthesis|positive regulation of ecdysteroid formation|positive regulation of ecdysteroid biosynthesis|up regulation of ecdysteroid biosynthetic process|upregulation of ecdysteroid biosynthetic process|stimulation of ecdysteroid biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ecdysteroids. GO:0070954 negative regulation of neutrophil mediated cytotoxicity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070954 down-regulation of neutrophil mediated cytotoxicity|downregulation of neutrophil mediated cytotoxicity|down regulation of neutrophil mediated cytotoxicity|inhibition of neutrophil mediated cytotoxicity|negative regulation of neutrophil mediated cell killing Any process that decreases the frequency, rate or extent of the directed killing of a target cell by a neutrophil. GO:0045999 negative regulation of ecdysteroid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045999 down-regulation of ecdysteroid secretion|inhibition of ecdysteroid secretion|down regulation of ecdysteroid secretion|downregulation of ecdysteroid secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of ecdysteroid. GO:0070955 negative regulation of neutrophil mediated killing of symbiont cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070955 down-regulation of neutrophil mediated killing of symbiont cell|downregulation of neutrophil mediated killing of symbiont cell|down regulation of neutrophil mediated killing of symbiont cell|inhibition of neutrophil mediated killing of symbiont cell Any process that decreases the frequency, rate or extent of the directed killing of a symbiont target cell by a neutrophil. GO:0031344 regulation of cell projection organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031344 regulation of cell projection organization and biogenesis|regulation of cell projection organisation Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections. GO:0070952 regulation of neutrophil mediated killing of gram-positive bacterium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070952 Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a gram-positive bacterium, the directed killing of a gram-positive bacterium by a neutrophil. GO:0070953 regulation of neutrophil mediated killing of fungus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070953 Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a fungal cell, the directed killing of a fungal cell by a neutrophil. GO:0031345 negative regulation of cell projection organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031345 down-regulation of cell projection organization|negative regulation of cell projection organization and biogenesis|downregulation of cell projection organization|inhibition of cell projection organization|down regulation of cell projection organization|negative regulation of cell projection organisation Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections. GO:0070950 regulation of neutrophil mediated killing of bacterium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070950 Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a bacterium, the directed killing of a bacterium by a neutrophil. GO:0031342 negative regulation of cell killing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031342 down-regulation of cell killing|downregulation of cell killing|down regulation of cell killing|inhibition of cell killing Any process that stops, prevents, or reduces the frequency, rate or extent of cell killing. GO:0070951 regulation of neutrophil mediated killing of gram-negative bacterium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070951 Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a gram-negative bacterium, the directed killing of a gram-negative bacterium by a neutrophil. GO:0031343 positive regulation of cell killing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031343 up regulation of cell killing|upregulation of cell killing|stimulation of cell killing|activation of cell killing|up-regulation of cell killing Any process that activates or increases the frequency, rate or extent of cell killing. GO:0031340 positive regulation of vesicle fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031340 up regulation of vesicle fusion|upregulation of vesicle fusion|stimulation of vesicle fusion|up-regulation of vesicle fusion|activation of vesicle fusion Any process that activates or increases the frequency, rate or extent of vesicle fusion. GO:0031341 regulation of cell killing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031341 Any process that modulates the frequency, rate or extent of cell killing, the process in which a cell brings about the death of another cell, either in the same or a different organism. GO:0031339 negative regulation of vesicle fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031339 inhibition of vesicle fusion|down-regulation of vesicle fusion|downregulation of vesicle fusion|down regulation of vesicle fusion Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle fusion. GO:0031337 positive regulation of sulfur amino acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031337 upregulation of sulfur amino acid metabolic process|up regulation of sulfur amino acid metabolic process|activation of sulfur amino acid metabolic process|stimulation of sulfur amino acid metabolic process|up-regulation of sulfur amino acid metabolic process|positive regulation of sulfur amino acid metabolism Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids. GO:0031338 regulation of vesicle fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031338 Any process that modulates the frequency, rate or extent of vesicle fusion. GO:0031335 regulation of sulfur amino acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031335 regulation of sulfur amino acid metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids. GO:0031336 negative regulation of sulfur amino acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031336 down regulation of sulfur amino acid metabolic process|downregulation of sulfur amino acid metabolic process|down-regulation of sulfur amino acid metabolic process|inhibition of sulfur amino acid metabolic process|negative regulation of sulfur amino acid metabolism Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids. GO:0006399 tRNA metabolic process biolink:BiologicalProcess go-plus goslim_drosophila|goslim_generic|goslim_pombe|goslim_chembl http://purl.obolibrary.org/obo/GO_0006399 tRNA metabolism The chemical reactions and pathways involving tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. Transfer RNA is characterized by the presence of many unusual minor bases, the function of which has not been completely established. GO:0006397 mRNA processing biolink:BiologicalProcess go-plus goslim_generic|goslim_chembl|goslim_yeast http://purl.obolibrary.org/obo/GO_0006397 mRNA maturation Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide. GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006398 histone mRNA 3' end processing Any mRNA 3'-end processing that involves the binding to and cleavage of a stem-loop structure. For example, histone mRNAs contain a highly conserved stem-loop sequence at the 3' end of the mRNA with a 6 base pairs (bp) stem and a 4-nt loop. The mRNA is cleaved between these two elements, after the fourth or fifth nucleotide, which is typically an adenosine. GO:0006395 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006395 GO:0006396 RNA processing biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0006396 Wikipedia:Post-transcriptional_modification Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules. GO:0006393 termination of mitochondrial transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006393 mitochondrial transcription termination|RNA transcription termination from mitochondrial promoter The process in which the synthesis of an RNA molecule using a mitochondrial DNA template is completed. GO:0006394 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006394 GO:0070949 regulation of neutrophil mediated killing of symbiont cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070949 Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a symbiont cell, the directed killing of a symbiont target cell by a neutrophil. GO:0070947 neutrophil-mediated killing of fungus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070947 neutrophil mediated killing of fungus The directed killing of a fungal cell by a neutrophil. GO:0070948 regulation of neutrophil mediated cytotoxicity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070948 regulation of neutrophil mediated cell killing Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a target cell, the directed killing of a target cell by a neutrophil. GO:0070945 neutrophil-mediated killing of gram-negative bacterium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070945 neutrophil mediated killing of gram-negative bacterium The directed killing of a gram-negative bacterium by a neutrophil. GO:0070946 neutrophil-mediated killing of gram-positive bacterium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070946 neutrophil mediated killing of gram-positive bacterium The directed killing of a gram-positive bacterium by a neutrophil. GO:0070943 neutrophil-mediated killing of symbiont cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070943 neutrophil mediated killing of symbiont cell The directed killing of a symbiont target cell by a neutrophil. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0070944 neutrophil-mediated killing of bacterium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070944 neutrophil mediated killing of bacterium The directed killing of a bacterium by a neutrophil. GO:0031333 negative regulation of protein-containing complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031333 down-regulation of protein complex assembly|negative regulation of protein complex assembly|downregulation of protein complex assembly|down regulation of protein complex assembly|inhibition of protein complex assembly Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly. GO:0070941 eisosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070941 The aggregation, arrangement and bonding together of a set of components to form an eisosome, a cell part that is composed of the eisosome membrane and eisosome filaments. The eisosome membrane, also called the MCC domain, is a furrow-like plasma membrane sub-domain with associated integral transmembrane proteins. The eisosome filaments form a scaffolding lattice on the cytoplasmic face of the membrane. GO:0031334 positive regulation of protein-containing complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031334 stimulation of protein complex assembly|up-regulation of protein complex assembly|activation of protein complex assembly|up regulation of protein complex assembly|positive regulation of protein complex assembly|upregulation of protein complex assembly Any process that activates or increases the frequency, rate or extent of protein complex assembly. GO:0070942 neutrophil mediated cytotoxicity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070942 neutrophil mediated cell killing The directed killing of a target cell by a neutrophil. GO:0031331 positive regulation of cellular catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031331 upregulation of cellular catabolic process|stimulation of cellular catabolic process|up-regulation of cellular catabolic process|activation of cellular catabolic process|positive regulation of cellular catabolism|positive regulation of cellular degradation|positive regulation of cellular breakdown|up regulation of cellular catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells. GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070940 CTD domain dephosphorylation of RNA polymerase II|generation of II(A) form of RNA polymerase II|generation of hypophosphorylated CTD of RNA polymerase II The process of removing a phosphate group from an amino acid residue in the C-terminal domain of RNA polymerase II. Some dephosphorylation occurs during transcription while some may occur after the enzyme is released from the template in order to prepare it for the beginning of the transcription cycle again. RNA polymerase II with little or no phosphorylation is referred to as the hypophosphorylated or II(A) form. GO:0031332 RNAi effector complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0031332 Any protein complex that mediates the effects of small interfering RNAs on gene expression. Most known examples contain one or more members of the Argonaute family of proteins. GO:0031330 negative regulation of cellular catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031330 down regulation of cellular catabolic process|inhibition of cellular catabolic process|negative regulation of cellular degradation|negative regulation of cellular breakdown|negative regulation of cellular catabolism|down-regulation of cellular catabolic process|downregulation of cellular catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells. GO:0031328 positive regulation of cellular biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031328 up regulation of cellular biosynthetic process|activation of cellular biosynthetic process|positive regulation of cellular biosynthesis|stimulation of cellular biosynthetic process|up-regulation of cellular biosynthetic process|positive regulation of cellular anabolism|positive regulation of cellular synthesis|positive regulation of cellular formation|upregulation of cellular biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. GO:0031329 regulation of cellular catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031329 regulation of cellular degradation|regulation of cellular breakdown|regulation of cellular catabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells. GO:0031326 regulation of cellular biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031326 regulation of cellular anabolism|regulation of cellular synthesis|regulation of cellular biosynthesis|regulation of cellular formation Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. GO:0031327 negative regulation of cellular biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031327 downregulation of cellular biosynthetic process|down-regulation of cellular biosynthetic process|negative regulation of cellular biosynthesis|negative regulation of cellular anabolism|inhibition of cellular biosynthetic process|negative regulation of cellular synthesis|negative regulation of cellular formation|down regulation of cellular biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. GO:0031324 negative regulation of cellular metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031324 down-regulation of cellular metabolic process|downregulation of cellular metabolic process|negative regulation of cellular metabolism|down regulation of cellular metabolic process|inhibition of cellular metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. GO:0006368 transcription elongation from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006368 RNA polymerase II transcription elongation factor activity|RNA elongation from Pol II promoter The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase II promoter by the addition of ribonucleotides catalyzed by RNA polymerase II. GO:0006369 termination of RNA polymerase II transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006369 transcription termination from RNA polymerase II promoter|RNA polymerase II transcription termination|transcription termination from Pol II promoter|RNA polymerase II transcription termination factor activity|RNA 3'-end formation by RNA polymerase II The process in which the synthesis of an RNA molecule by RNA polymerase II using a DNA template is completed. GO:0031325 positive regulation of cellular metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031325 up regulation of cellular metabolic process|positive regulation of cellular metabolism|upregulation of cellular metabolic process|stimulation of cellular metabolic process|up-regulation of cellular metabolic process|activation of cellular metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. GO:0006366 transcription by RNA polymerase II biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0006366 gene-specific transcription from RNA polymerase II promoter|general transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|transcription from Pol II promoter|RNA polymerase II transcription factor activity|specific transcription from RNA polymerase II promoter The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs). GO:0006367 transcription initiation from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006367 transcription initiation from Pol II promoter Any process involved in the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription. GO:0006364 rRNA processing biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0006364 35S primary transcript processing Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules. GO:0006365 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006365 GO:0006362 transcription elongation from RNA polymerase I promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006362 RNA polymerase I transcription elongation factor activity|RNA elongation from Pol I promoter The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase I specific promoter by the addition of ribonucleotides catalyzed by RNA polymerase I. GO:0006363 termination of RNA polymerase I transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006363 RNA polymerase I transcription termination|transcription termination from RNA polymerase I promoter|RNA polymerase I transcription termination factor activity|transcription termination from Pol I promoter|termination of RNA polymerase I transcription from promoter for nuclear large rRNA transcript The process in which the synthesis of an RNA molecule by RNA polymerase I using a DNA template is completed. RNAP I termination requires binding of a terminator protein so specific sequences downstream of the transcription unit. GO:0006360 transcription by RNA polymerase I biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0006360 RNA polymerase I transcription factor activity|transcription from Pol I promoter|transcription from RNA polymerase I promoter The synthesis of RNA from a DNA template by RNA polymerase I (RNAP I), originating at an RNAP I promoter. GO:0006361 transcription initiation from RNA polymerase I promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006361 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript|transcription initiation from Pol I promoter Any process involved in the assembly of the RNA polymerase I preinitiation complex (PIC) at an RNA polymerase I promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription. GO:0006370 7-methylguanosine mRNA capping biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006370 5' mRNA capping|5'-end processing|5' end capping|5'-end mRNA processing|mRNA capping Addition of the 7-methylguanosine cap to the 5' end of a nascent messenger RNA transcript. GO:0070978 voltage-gated calcium channel complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070978 Cellular protein complex assembly that results in the formation of a voltage-gated calcium channel complex. GO:0070979 protein K11-linked ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070979 A protein ubiquitination process in which ubiquitin monomers are attached to a protein, and then ubiquitin polymers are formed by linkages between lysine residues at position 11 of the ubiquitin monomers. K11-linked polyubiquitination targets the substrate protein for degradation. The anaphase-promoting complex promotes the degradation of mitotic regulators by assembling K11-linked polyubiquitin chains. GO:0070976 TIR domain binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0070976 Toll-Interleukin receptor domain binding Interacting selectively and non-covalently with a Toll-Interleukin receptor (TIR) domain of a protein. The TIR domain is an intracellular 200 residue domain that is found in the Toll protein, the interleukin-1 receptor (IL-1R), and MyD88; it contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. GO:0070977 bone maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070977 A developmental process, independent of morphogenetic (shape) change, that is required for bone to attain its fully functional state. GO:0031322 ascospore-type prospore-specific spindle pole body remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031322 sporulation-specific spindle pole body remodeling|prospore-specific spindle pole body remodeling|forespore specific spindle pole body remodeling|ascospore-type prospore-specific spindle pole body modification|ascospore-type prospore-specific spindle pole body remodelling|forespore-specific spindle pole body remodeling A spindle pole body (SPB) organization process that takes place during the second meiotic division during ascospore formation and results in the structural reorganization of the SPB; includes the recruitment of sporulation-specific proteins to the outer plaque to form the meiotic outer plaque (MOP). GO:0070974 POU domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070974 Interacting selectively and non-covalently with a POU domain of a protein. The POU domain is a bipartite DNA binding domain composed of two subunits separated by a non-conserved region of 15-55 amino acids; it is found in several eukaryotic transcription factors. GO:0031323 regulation of cellular metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031323 regulation of cellular metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. GO:0070975 FHA domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070975 Forkhead-associated domain binding Interacting selectively and non-covalently with a FHA domain of a protein. The FHA domain is a phosphopeptide recognition domain found in many regulatory proteins, and consists of approximately 80-100 amino acid residues folded into an 11-stranded beta sandwich. GO:0070972 protein localization to endoplasmic reticulum biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070972 protein localization in endoplasmic reticulum|protein localization in ER|protein localisation in endoplasmic reticulum A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum. GO:0031320 hexitol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031320 Catalysis of the reaction: hexitol + acceptor = hexose + reduced acceptor. GO:0070973 protein localization to endoplasmic reticulum exit site biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070973 protein localization to ER exit site|protein localisation to endoplasmic reticulum exit site A process in which a protein is transported to, or maintained in, a location at an endoplasmic reticulum exit site. GO:0031321 ascospore-type prospore assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031321 ascospore-type prospore formation|forespore formation During ascospore formation, the process in which each haploid nucleus becomes encapsulated by a double membrane. GO:0070970 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0070970 GO:0070971 endoplasmic reticulum exit site biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070971 NIF_Subcellular:sao124393998 transitional ER|ER exit site An endoplasmic reticulum part at which COPII-coated vesicles are produced. GO:0031319 detection of cAMP biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031319 detection of 3',5'-cAMP|detection of adenosine 3',5'-cyclophosphate|3',5'-cAMP sensing|cAMP sensing|detection of cyclic AMP|3',5'-cAMP detection|cAMP detection|detection of 3',5' cAMP|cyclic AMP detection The series of events in which a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus is received by a cell and converted into a molecular signal; cAMP is the nucleotide cyclic AMP. OBA:0005997 peroxisome morphology biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0005997 morphology of peroxisome The morphology of a peroxisome. GO:0031317 tripartite ATP-independent periplasmic transporter complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031317 TRAP-T transporter complex|TRAP transporter complex A complex consisting of two membrane proteins and one extracytoplasmic solute receptor. Such transporters transport a variety of substrates without direct ATP power, instead using energy from ion gradients. GO:0021990 neural plate formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021990 The formation of the flat, thickened layer of ectodermal cells known as the neural plate. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system. GO:0031318 detection of folic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031318 detection of folate|folate sensing|folate detection|folic acid sensing|folic acid detection The series of events in which a folic acid stimulus is received by a cell and converted into a molecular signal. GO:0021991 neural plate thickening biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021991 The process of apical-basal elongation of individual ectodermal cells during the formation of the neural placode. GO:0021992 cell proliferation involved in neural plate elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021992 The process of expansion of cell numbers in the neural plate due to cell division of progenitor cells preferentially in the rostrocaudal direction, resulting in the elongation of the tissue. GO:0031315 extrinsic component of mitochondrial outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031315 extrinsic to mitochondrial outer membrane The component of a mitochondrial outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:0031316 extrinsic component of nuclear outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031316 extrinsic to nuclear outer membrane The component of a nuclear outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:0021993 initiation of neural tube closure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021993 The process in which closure points are established at multiple points and along the neural rostrocaudal axis. GO:0006379 mRNA cleavage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006379 cleavage stimulation factor activity Any process in which a pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner. GO:0031313 extrinsic component of endosome membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031313 extrinsic to endosome membrane The component of an endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:0021994 progression of neural tube closure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021994 The process in which the neural folds are fused extending from the initial closure points. GO:0021995 neuropore closure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021995 The process of joining together the neural folds at either end of the neural tube. GO:0031314 extrinsic component of mitochondrial inner membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031314 extrinsic to mitochondrial inner membrane The component of mitochondrial inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:0006377 obsolete MATa1 (A1) pre-mRNA splicing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006377 MATa1 (A1) pre-mRNA splicing OBSOLETE. (Was not defined before being made obsolete). GO:0006378 mRNA polyadenylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006378 mRNA polyadenylylation|cleavage and polyadenylylation specificity factor activity The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript. GO:0006375 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006375 GO:0006376 mRNA splice site selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006376 spliceosomal commitment complex biosynthesis|spliceosomal E complex formation|spliceosomal E complex biosynthesis|spliceosomal commitment complex formation Selection of a splice site by components of the assembling spliceosome. GO:0006373 obsolete 3'-splice site cleavage, exon ligation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006373 3'-splice site cleavage, exon ligation OBSOLETE. (Was not defined before being made obsolete). GO:0006374 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006374 GO:0006371 obsolete mRNA splicing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006371 mRNA splicing OBSOLETE. The process in which excision of introns from the primary transcript of messenger RNA (mRNA) is followed by ligation of the two exon termini exposed by removal of each intron, so that mRNA consisting only of the joined exons is produced. GO:0006372 obsolete lariat formation, 5'-splice site cleavage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006372 lariat formation, 5'-splice site cleavage OBSOLETE. (Was not defined before being made obsolete). GO:0006380 obsolete poly-A binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006380 poly-A binding OBSOLETE. (Was not defined before being made obsolete). GO:0006381 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006381 GO:0070969 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0070969 CHEBI:141855 5'-end NTP-ribonucleotide(5-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_141855 GO:0070967 coenzyme F420 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070967 Interacting selectively and non-covalently with F420, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes. GO:0070968 pyrroloquinoline quinone binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070968 PQQ binding Interacting selectively and non-covalently with pyrroloquinoline quinone, PQQ, the coenzyme or the prosthetic group of certain alcohol dehydrogenases and glucose dehydrogenases. GO:0070965 positive regulation of neutrophil mediated killing of fungus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070965 up regulation of neutrophil mediated killing of fungus|activation of neutrophil mediated killing of fungus|stimulation of neutrophil mediated killing of fungus|up-regulation of neutrophil mediated killing of fungus|upregulation of neutrophil mediated killing of fungus Any process that increases the frequency, rate or extent of the directed killing of a fungal cell by a neutrophil. GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070966 no-go decay|nuclear-transcribed mRNA breakdown, no-go decay|nuclear-transcribed mRNA degradation, no-go decay|no-go mRNA decay|nuclear-transcribed mRNA catabolism, no-go decay The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA with stalls in translation elongation. GO:0031311 intrinsic component of contractile vacuolar membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031311 intrinsic to contractile vacuolar membrane The component of the contractile vacuolar membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0021996 lamina terminalis formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021996 The process in which the anterior-most portion of the neural axis is formed by closure of the anterior neuropore. GO:0070963 positive regulation of neutrophil mediated killing of gram-negative bacterium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070963 up regulation of neutrophil mediated killing of gram-negative bacterium|upregulation of neutrophil mediated killing of gram-negative bacterium|stimulation of neutrophil mediated killing of gram-negative bacterium|up-regulation of neutrophil mediated killing of gram-negative bacterium|activation of neutrophil mediated killing of gram-negative bacterium Any process that increases the frequency, rate or extent of the directed killing of a gram-negative bacterium by a neutrophil. GO:0031312 extrinsic component of organelle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031312 extrinsic to organelle membrane The component of an organelle membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:0070964 positive regulation of neutrophil mediated killing of gram-positive bacterium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070964 up regulation of neutrophil mediated killing of gram-positive bacterium|upregulation of neutrophil mediated killing of gram-positive bacterium|stimulation of neutrophil mediated killing of gram-positive bacterium|up-regulation of neutrophil mediated killing of gram-positive bacterium|activation of neutrophil mediated killing of gram-positive bacterium Any process that increases the frequency, rate or extent of the directed killing of a gram-positive bacterium by a neutrophil. GO:0021997 neural plate axis specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021997 neural plate axis determination The pattern specification process in which the axes of the nervous system are established. GO:0070961 positive regulation of neutrophil mediated killing of symbiont cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070961 upregulation of neutrophil mediated killing of symbiont cell|stimulation of neutrophil mediated killing of symbiont cell|up-regulation of neutrophil mediated killing of symbiont cell|activation of neutrophil mediated killing of symbiont cell|up regulation of neutrophil mediated killing of symbiont cell Any process that increases the frequency, rate or extent of the directed killing of a symbiont target cell by a neutrophil. GO:0021998 neural plate mediolateral regionalization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021998 neural plate mediolateral pattern formation The process that regulates the coordinated growth and differentiation that establishes the non-random mediolateral spatial arrangement of the neural plate. GO:0031310 intrinsic component of vacuolar membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031310 intrinsic to vacuolar membrane The component of the vacuolar membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0070962 positive regulation of neutrophil mediated killing of bacterium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070962 stimulation of neutrophil mediated killing of bacterium|up-regulation of neutrophil mediated killing of bacterium|activation of neutrophil mediated killing of bacterium|up regulation of neutrophil mediated killing of bacterium|upregulation of neutrophil mediated killing of bacterium Any process that increases the frequency, rate or extent of the directed killing of a bacterium by a neutrophil. GO:0021999 neural plate anterior/posterior regionalization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021999 neural plate anterior/posterior pattern formation The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the neural plate. GO:0070960 positive regulation of neutrophil mediated cytotoxicity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070960 up regulation of neutrophil mediated cytotoxicity|upregulation of neutrophil mediated cytotoxicity|positive regulation of neutrophil mediated cell killing|stimulation of neutrophil mediated cytotoxicity|up-regulation of neutrophil mediated cytotoxicity|activation of neutrophil mediated cytotoxicity Any process that increases the frequency, rate or extent of the directed killing of a target cell by a neutrophil. GO:0031308 intrinsic component of nuclear outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031308 intrinsic to nuclear outer membrane The component of the nuclear outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0031309 integral component of nuclear outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031309 integral to nuclear outer membrane The component of the nuclear outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0031306 intrinsic component of mitochondrial outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031306 intrinsic to mitochondrial outer membrane The component of the mitochondrial outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0031307 integral component of mitochondrial outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031307 integral to mitochondrial outer membrane The component of the mitochondrial outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0021980 subpallium cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021980 The orderly movement of cells from one site to another in the subpallium. GO:0021981 subpallium radially oriented migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021981 The migration of cells in the developing subpallium in which cells move from the ventricular and/or subventricular zone toward the surface of the brain. GO:0006348 chromatin silencing at telomere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006348 telomere chromatin silencing|heterochromatic silencing at telomere|Telomere Position Effect|telomeric silencing Repression of transcription of telomeric DNA by altering the structure of chromatin. GO:0031304 intrinsic component of mitochondrial inner membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031304 intrinsic to mitochondrial inner membrane The component of the mitochondrial inner membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0021982 pineal gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021982 epiphysis development The progression of the pineal gland over time from its initial formation until its mature state. The pineal gland is an endocrine gland that secretes melatonin and is involved in circadian rhythms. GO:0031305 integral component of mitochondrial inner membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031305 integral to mitochondrial inner membrane The component of the mitochondrial inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0006349 regulation of gene expression by genetic imprinting biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006349 Wikipedia:Genomic_imprinting regulation of gene expression by DNA imprinting Heritable alterations in the activity of a gene that depend on whether it passed through the paternal or the maternal germline, but that are not encoded by DNA itself. SO:0002140 early_origin_of_replication biolink:SequenceFeature go-plus http://purl.obolibrary.org/obo/SO_0002140 early origin|early origin of replication|early replication origin An origin of replication that initiates early in S phase. GO:0006346 DNA methylation-dependent heterochromatin assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006346 methylation-dependent chromatin silencing|methylation-dependent heterochromatic silencing Repression of transcription by methylation of DNA, leading to the formation of heterochromatin. GO:0031302 intrinsic component of endosome membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031302 intrinsic to endosome membrane The component of the endosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0021983 pituitary gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021983 hypophysis development The progression of the pituitary gland over time from its initial formation until its mature state. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands. GO:0031303 integral component of endosome membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031303 integral to endosome membrane The component of the endosome membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0006347 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006347 SO:0002141 late_origin_of_replication biolink:SequenceFeature go-plus http://purl.obolibrary.org/obo/SO_0002141 late origin of replication|late origin|late replication origin An origin of replication that initiates late in S phase. GO:0021984 adenohypophysis development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021984 adenophysis development|anterior pituitary development|anterior pituitary gland development The progression of the adenohypophysis over time from its initial formation until its mature state. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus. GO:0006344 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006344 GO:0006345 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006345 GO:0006342 chromatin silencing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006342 TGS|chromatin-mediated silencing|transcriptional gene silencing|chromatin-mediated maintenance of transcriptional inactivation|heterochromatic silencing Repression of transcription by altering the structure of chromatin, e.g. by conversion of large regions of DNA into an inaccessible state often called heterochromatin. GO:0006343 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006343 GO:0006340 obsolete negative regulation of transcription of homeotic gene (Polycomb group) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006340 negative regulation of transcription of homeotic gene (Polycomb group) OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription of homeotic genes of the Polycomb group. GO:0006341 obsolete chromatin insulator sequence binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006341 chromatin insulator sequence binding OBSOLETE. (Was not defined before being made obsolete). OBO:GOCHE_37848 substance with plant hormone role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_37848 GO:0070998 sensory perception of gravity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070998 The series of events required for an organism to receive a gravitational stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. GO:0070999 detection of mechanical stimulus involved in sensory perception of gravity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070999 The series of events involved in the perception of gravity in which a sensory mechanical stimulus is received and converted into a molecular signal. GO:0021985 neurohypophysis development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021985 posterior pituitary development|neurophysis development|posterior pituitary gland development The progression of the neurohypophysis over time from its initial formation until its mature state. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation. GO:0070996 type 1 melanocortin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070996 type 1 melanocortin receptor ligand Interacting selectively and non-covalently with a type 1 melanocortin receptor. GO:0031300 intrinsic component of organelle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031300 intrinsic to organelle membrane The component of the organelle membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0021986 habenula development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021986 The progression of the habenula over time from its initial formation until its mature state. The habenula is the group of nuclei that makes up the stalk of the pineal gland. GO:0070997 neuron death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070997 neuron cell death|neuronal cell death The process of cell death in a neuron. GO:0031301 integral component of organelle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031301 integral to organelle membrane The component of the organelle membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0070994 detection of oxidative stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070994 The series of events in which a stimulus indicating oxidative stress is received and converted into a molecular signal. GO:0021987 cerebral cortex development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021987 neocortex development|corticogenesis The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon. GO:0070995 NADPH oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070995 NADP (reduced) dehydrogenation|reduced nicotinamide adenine dinucleotide phosphate dehydrogenation|NADP (reduced) oxidation|reduced nicotinamide adenine dinucleotide phosphate oxidation|NADPH dehydrogenation|reduced NADP dehydrogenation|reduced NADP oxidation A metabolic process that results in the oxidation of reduced nicotinamide adenine dinucleotide, NADPH, to the oxidized form, NADP. GO:0021988 olfactory lobe development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021988 The progression of the olfactory lobe over time from its initial formation until its mature state. The olfactory lobe is the area of the brain that process the neural inputs for the sense of smell. GO:0070992 translation initiation complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070992 A ribonucleoprotein complex that contains a ribosome, mRNA, and initiator tRNA; the functional ribosome is at the AUG, with the methionyl/formyl-methionyl-tRNA positioned at the P site. GO:0021989 olfactory cortex development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021989 The progression of the olfactory cortex over time from its initial formation until its mature state. The olfactory cortex is involved in the perception of smell. It receives input from the olfactory bulb and is responsible for the identification of odors. GO:0070993 translation preinitiation complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070993 A ribonucleoprotein complex that contains the small ribosomal subunit, a translation initiation ternary complex (i.e. an initiator tRNA, GTP, and an IF2 or eIF2 complex), and an mRNA. GO:0070990 snRNP binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070990 Interacting selectively and non-covalently with any part of a small nuclear ribonucleoprotein particle. GO:0070991 medium-chain-acyl-CoA dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070991 EC:1.3.99.- MCAD activity Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor, where the acyl group is a medium-chain fatty acid residue. A medium chain fatty acid is any fatty acid with a chain length of between C6 and C12. GO:0006359 regulation of transcription by RNA polymerase III biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006359 regulation of transcription from RNA polymerase III promoter|regulation of transcription from Pol III promoter Any process that modulates the frequency, rate or extent of transcription mediated by RNA ploymerase III. GO:0021970 corticospinal neuron axon guidance through the basilar pons biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021970 corticospinal neuron axon pathfinding through the basilar pons The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the cerebral peduncle through the basilar pons in response to a combination of attractive and repulsive cues. GO:0021971 corticospinal neuron axon guidance through the medullary pyramid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021971 corticospinal neuron axon pathfinding through the medullary pyramid The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the basilar pons through the medullary pyramid in response to a combination of attractive and repulsive cues. GO:0021972 corticospinal neuron axon guidance through spinal cord biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021972 corticospinal neuron axon pathfinding through spinal cord The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after decussation through the spinal cord in response to a combination of attractive and repulsive cues. GO:0006357 regulation of transcription by RNA polymerase II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006357 global transcription regulation from Pol II promoter|regulation of gene-specific transcription from RNA polymerase II promoter|regulation of transcription from Pol II promoter|regulation of transcription from RNA polymerase II promoter|regulation of global transcription from Pol II promoter|regulation of transcription from RNA polymerase II promoter, global Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. GO:0021973 corticospinal neuron axon decussation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021973 The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed to cross the midline to the contralateral side. GO:0006358 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006358 GO:0006355 regulation of transcription, DNA-templated biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006355 transcriptional control|regulation of cellular transcription, DNA-dependent|regulation of gene-specific transcription|regulation of transcription, DNA-dependent Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0006356 regulation of transcription by RNA polymerase I biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006356 regulation of transcription from Pol I promoter|regulation of transcription from RNA polymerase I promoter Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase I. GO:0006353 DNA-templated transcription, termination biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0006353 transcription termination factor activity|termination of transcription, DNA-dependent|termination of DNA-dependent transcription|DNA-dependent transcription, termination|transcription termination, DNA-dependent|transcriptional complex disassembly The cellular process that completes DNA-templated transcription; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA. GO:0006354 DNA-templated transcription, elongation biolink:BiologicalProcess go-plus goslim_yeast|goslim_pir http://purl.obolibrary.org/obo/GO_0006354 DNA-dependent transcription, elongation|transcription elongation, DNA-dependent|RNA elongation|transcriptional elongation, DNA-dependent The extension of an RNA molecule after transcription initiation and promoter clearance at a DNA-dependent RNA polymerase promoter by the addition of ribonucleotides catalyzed by an RNA polymerase. GO:0006351 transcription, DNA-templated biolink:BiologicalProcess go-plus goslim_pir|goslim_drosophila|goslim_aspergillus|goslim_metagenomics|goslim_pombe http://purl.obolibrary.org/obo/GO_0006351 Wikipedia:Transcription_(genetics) transcription, DNA-dependent|cellular transcription|transcription|DNA-dependent transcription|cellular transcription, DNA-dependent|transcription regulator activity The cellular synthesis of RNA on a template of DNA. GO:0006352 DNA-templated transcription, initiation biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0006352 initiation of transcription, DNA-dependent|transcription initiation factor activity|transcription initiation, DNA-dependent|DNA-dependent RNA polymerase complex assembly at promoter|DNA-dependent transcription, initiation|initiation of DNA-dependent transcription Any process involved in the assembly of the RNA polymerase preinitiation complex (PIC) at the core promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. The initiation phase ends just before and does not include promoter clearance, or release, which is the transition between the initiation and elongation phases of transcription. GO:0006350 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006350 CHEBI:32197 tetracenomycin A2 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32197 GO:0070989 oxidative demethylation biolink:BiologicalProcess go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0070989 The process of removing one or more methyl groups from a molecule, involving the oxidation (i.e. electron loss) of one or more atoms in the substrate. GO:0070987 error-free translesion synthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070987 The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions but does not causes an increase in the endogenous mutation level. For S. cerevisiae, RAD30 encodes DNA polymerase eta, which incorporates two adenines. When incorporated across a thymine-thymine dimer, it does not increase the endogenous mutation level. GO:0070988 demethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070988 The process of removing one or more methyl groups from a molecule. GO:0070985 transcription factor TFIIK complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070985 cyclin H-CDK7 complex|Mcs6/Mcs2/Pmh1 complex|TFIIK complex A transcription factor complex that forms part of the holo TFIIH complex. In Saccharomyces/human, TFIIK contains Ccl1p/Cyclin H, Tfb3p/MAT1 and Kin28p/CDK7. GO:0021974 trigeminothalamic tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021974 Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in spinal cord towards target cells in the thalamus. This axonal process is a member of those that make up the trigeminothalamic tract, one of the major routes of nociceptive and temperature signaling from the face. GO:0021975 pons reticulospinal tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021975 Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the pons towards target cells in the spinal cord. GO:0070986 left/right axis specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070986 left-right axis specification|left/right axis determination The establishment, maintenance and elaboration of the left/right axis. The left/right axis is defined by a line that runs orthogonal to both the anterior/posterior and dorsal/ventral axes. Each side is defined from the viewpoint of the organism rather of the observer (as per anatomical axes). GO:0021976 medulla reticulospinal tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021976 Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the medulla towards target cells in the spinal cord. GO:0070983 dendrite guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070983 dendritic guidance The process in which the migration of a dendrite is directed to a specific target site in response to a combination of attractive and repulsive cues. GO:0021977 tectospinal tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021977 Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the superior colliculus of the midbrain towards target cells in the ventral spinal cord. GO:0070984 SET domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070984 SET binding Interacting selectively and non-covalently with a SET domain of a protein. SET domains are named after three Drosophila proteins that contain this domain: Su(var), E(z) and trithorax. SET domains are associated with histone lysine methylation. GO:0021978 telencephalon regionalization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021978 The regionalization process that creates areas within the forebrain that will direct the behavior of cell migration in differentiation as the telencephalon develops. GO:0070981 L-asparagine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070981 L-asparagine formation|L-asparagine anabolism|L-asparagine synthesis|L-asparagine biosynthesis The chemical reactions and pathways resulting in the formation of asparagine, (2S)-2-amino-3-carbamoylpropanoic acid. GO:0021979 hypothalamus cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021979 The differentiation of cells that will contribute to the structure and function of the hypothalamus. GO:0070982 L-asparagine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070982 L-asparagine metabolism The chemical reactions and pathways involving L-asparagine, (2S)-2-amino-3-carbamoylpropanoic acid. GO:0070980 biphenyl catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070980 biphenyl breakdown|biphenyl catabolism|biphenyl degradation The chemical reactions and pathways resulting in the breakdown of biphenyl, a toxic aromatic hydrocarbon used as a heat transfer agent, as a fungistat in packaging citrus fruits and in plant disease control. Biphenyl can be chlorinated with 1-10 chlorine molecules to form polychlorinated biphenyls (PCBs). GO:0006328 obsolete AT binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006328 AT binding OBSOLETE. (Was not defined before being made obsolete). GO:0006329 obsolete satellite DNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006329 satellite DNA binding OBSOLETE. (Was not defined before being made obsolete). GO:0006326 obsolete bent DNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006326 bent DNA binding OBSOLETE. (Was not defined before being made obsolete). GO:0021960 anterior commissure morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021960 Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in one half of the cerebral cortex towards target cells in the contralateral half. This axonal process is a member of those that make up the anterior commissure, a small midline fiber tract that lies at the anterior end of the corpus callosum. GO:0006327 obsolete random coil binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006327 random coil binding OBSOLETE. (Was not defined before being made obsolete). GO:0006324 obsolete S phase-specific histone modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006324 S phase-specific histone modification|S-phase-specific histone modification OBSOLETE. The covalent alteration of one or more amino acid residues within a histone protein that takes place during, and results in a modification pattern characteristic of, S phase of the cell cycle. GO:0021961 posterior commissure morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021961 Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the midbrain towards target cells in the diencephalon. GO:0006325 chromatin organization biolink:BiologicalProcess go-plus goslim_pombe|goslim_yeast http://purl.obolibrary.org/obo/GO_0006325 establishment or maintenance of chromatin architecture|chromatin organisation|chromatin modification Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin. GO:0021962 vestibulospinal tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021962 Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the vestibular nucleus of the pons towards target cells in the spinal cord. GO:0006322 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006322 GO:0006323 DNA packaging biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0006323 DNA organisation|DNA organization|DNA condensation Any process in which DNA and associated proteins are formed into a compact, orderly structure. GO:0006320 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006320 GO:0006321 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006321 CHEBI:32167 1,2-diacyl-3-(alpha-D-6-sulfoquinovosyl)-sn-glycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32167 GO:0021963 spinothalamic tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021963 dorsolateral tract of Lissauer morphogenesis Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the spinal cord towards target cells in the thalamus. This axonal process is a member of those that make up the spinothalamic tract, one of the major routes of nociceptive signaling. GO:0021964 rubrospinal tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021964 Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the red nucleus of the midbrain towards target cells in the spinal cord. GO:0021965 spinal cord ventral commissure morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021965 The process in which the anatomical structures of the spinal cord ventral commissure are generated and organized. GO:0021966 corticospinal neuron axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021966 corticospinal neuron axon pathfinding The process in which the migration of an axon growth cone of a neuron that is part of the corticospinal tract is directed from the cerebral cortex layer V to the spinal cord dorsal funiculus in response to a combination of attractive and repulsive cues. GO:0021967 corticospinal neuron axon guidance through the cerebral cortex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021967 corticospinal neuron axon pathfinding through the cerebral cortex The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed from its cell body in layer V through the cerebral cortex in response to a combination of attractive and repulsive cues. GO:0021968 corticospinal neuron axon guidance through the internal capsule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021968 corticospinal neuron axon pathfinding through the internal capsule The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the cerebral cortex through the internal capsule in response to a combination of attractive and repulsive cues. CHEBI:141828 3-hydroxy-L-asparagine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_141828 GO:0021969 corticospinal neuron axon guidance through the cerebral peduncle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021969 corticospinal neuron axon pathfinding through the cerebral peduncle The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the internal capsule through the cerebral peduncle in response to a combination of attractive and repulsive cues. GO:0006339 obsolete positive regulation of transcription of homeotic gene (trithorax group) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006339 positive regulation of transcription of homeotic gene (trithorax group) OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription of homeotic genes of the trithorax group. GO:0006337 nucleosome disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006337 The controlled breakdown of nucleosomes, the beadlike structural units of eukaryotic chromatin composed of histones and DNA. GO:0006338 chromatin remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006338 chromatin modeling|chromatin remodelling|chromatin modelling Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation. GO:0021950 chemorepulsion involved in precerebellar neuron migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021950 negative chemotaxis involved in precerebellar neuron migration The creation and reception of signals that repel a precerebellar neuron as a component of the process of tangential migration. GO:0006335 DNA replication-dependent nucleosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006335 The formation of nucleosomes on newly replicated DNA, coupled to strand elongation. GO:0021951 chemoattraction involved in precerebellar neuron migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021951 positive chemotaxis involved in precerebellar neuron migration The creation and reception of signals that guide a precerebellar neuron towards their signals, where this process is involved in tangential migration. GO:0006336 DNA replication-independent nucleosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006336 transcription-coupled nucleosome assembly The formation of nucleosomes outside the context of DNA replication. GO:0006333 chromatin assembly or disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006333 chromatin assembly/disassembly The formation or destruction of chromatin structures. GO:0006334 nucleosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006334 histone chaperone|nucleosome modeling The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA. GO:0006331 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006331 GO:0006332 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006332 GO:0006330 obsolete single-stranded DNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006330 single-stranded DNA binding OBSOLETE. (Was not defined before being made obsolete). GO:0021952 central nervous system projection neuron axonogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021952 central nervous system axon tract development Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells in a different central nervous system region. GO:0021953 central nervous system neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021953 The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the central nervous system. GO:0021954 central nervous system neuron development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021954 The process whose specific outcome is the progression of a neuron whose cell body is located in the central nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron. GO:0021955 central nervous system neuron axonogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021955 Generation of a long process from a neuron whose cell body resides in the central nervous system. The process carries efferent (outgoing) action potentials from the cell body towards target cells. GO:0021956 central nervous system interneuron axonogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021956 Generation of a long process that carries efferent (outgoing) action potentials from the cell body towards target cells from a neuron located in the central nervous system whose axons remain within a single brain region. GO:0021957 corticospinal tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021957 CST axonogenesis|corticospinal tract axonogenesis Generation of a long process of a pyramidal cell, that carries efferent (outgoing) action potentials from the cell body in cerebral cortex layer V towards target cells in the gray matter of the spinal cord. This axonal process is a member of those that make up the corticospinal tract. GO:0021958 gracilis tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021958 tract of Goll morphogenesis Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the dorsal root ganglion towards target cells in the medulla. This axonal process is a member of those that make up the gracilis tract, a group of axons that are from neurons involved in proprioception from the lower trunk and lower limb. CHEBI:141817 5-hydroxy-L-lysinium residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_141817 GO:0021959 cuneatus tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021959 tract of Burdach morphogenesis Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the dorsal root ganglion towards target cells in the medulla. This axonal process is a member of those that make up the cuneatus tract, a group of axons that are from neurons involved in proprioception from the upper trunk and upper limb. GO:0045916 negative regulation of complement activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045916 down-regulation of complement activation|inhibition of complement activation|negative regulation of complement cascade|down regulation of complement activation|downregulation of complement activation Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation. GO:0045917 positive regulation of complement activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045917 activation of complement activation|stimulation of complement activation|up-regulation of complement activation|positive regulation of complement cascade|upregulation of complement activation|up regulation of complement activation Any process that activates or increases the frequency, rate or extent of complement activation. GO:0045914 negative regulation of catecholamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045914 down regulation of catecholamine metabolic process|downregulation of catecholamine metabolic process|down-regulation of catecholamine metabolic process|negative regulation of catecholamine metabolism|inhibition of catecholamine metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catecholamine. GO:0045915 positive regulation of catecholamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045915 up regulation of catecholamine metabolic process|activation of catecholamine metabolic process|stimulation of catecholamine metabolic process|up-regulation of catecholamine metabolic process|positive regulation of catecholamine metabolism|upregulation of catecholamine metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catecholamine. GO:0045912 negative regulation of carbohydrate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045912 down-regulation of carbohydrate metabolic process|downregulation of carbohydrate metabolic process|down regulation of carbohydrate metabolic process|inhibition of carbohydrate metabolic process|negative regulation of carbohydrate metabolism Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate. GO:0045913 positive regulation of carbohydrate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045913 up regulation of carbohydrate metabolic process|upregulation of carbohydrate metabolic process|stimulation of carbohydrate metabolic process|positive regulation of carbohydrate metabolism|up-regulation of carbohydrate metabolic process|activation of carbohydrate metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate. GO:0045910 negative regulation of DNA recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045910 inhibition of DNA recombination|down regulation of DNA recombination|downregulation of DNA recombination|down-regulation of DNA recombination Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombination. GO:0045911 positive regulation of DNA recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045911 up-regulation of DNA recombination|upregulation of DNA recombination|up regulation of DNA recombination|activation of DNA recombination|stimulation of DNA recombination Any process that activates or increases the frequency, rate or extent of DNA recombination. GO:0045918 negative regulation of cytolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045918 down regulation of cytolysis|downregulation of cytolysis|down-regulation of cytolysis|inhibition of cytolysis Any process that stops, prevents, or reduces the frequency, rate or extent of cytolysis. GO:0045919 positive regulation of cytolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045919 upregulation of cytolysis|up regulation of cytolysis|activation of cytolysis|stimulation of cytolysis|up-regulation of cytolysis Any process that activates or increases the frequency, rate or extent of cytolysis. GO:0045920 negative regulation of exocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045920 down regulation of exocytosis|inhibition of exocytosis|down-regulation of exocytosis|downregulation of exocytosis Any process that stops, prevents, or reduces the frequency, rate or extent of exocytosis. GO:0045927 positive regulation of growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045927 up regulation of growth|upregulation of growth|stimulation of growth|up-regulation of growth|activation of growth Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism. GO:0045928 negative regulation of juvenile hormone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045928 inhibition of juvenile hormone metabolic process|negative regulation of juvenile hormone metabolism|down-regulation of juvenile hormone metabolic process|downregulation of juvenile hormone metabolic process|down regulation of juvenile hormone metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone. GO:0045925 positive regulation of female receptivity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045925 upregulation of female receptivity|stimulation of female receptivity|up-regulation of female receptivity|activation of female receptivity|up regulation of female receptivity Any process that activates or increases the receptiveness of a female to male advances. GO:0045926 negative regulation of growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045926 downregulation of growth|down regulation of growth|inhibition of growth|down-regulation of growth Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism. GO:0045923 positive regulation of fatty acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045923 up regulation of fatty acid metabolic process|positive regulation of fatty acid metabolism|upregulation of fatty acid metabolic process|stimulation of fatty acid metabolic process|activation of fatty acid metabolic process|up-regulation of fatty acid metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving fatty acids. GO:0045924 regulation of female receptivity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045924 female receptivity Any process that modulates the frequency, rate or extent of the willingness or readiness of a female to receive male advances. GO:0045921 positive regulation of exocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045921 upregulation of exocytosis|stimulation of exocytosis|up-regulation of exocytosis|activation of exocytosis|up regulation of exocytosis Any process that activates or increases the frequency, rate or extent of exocytosis. GO:0045922 negative regulation of fatty acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045922 down-regulation of fatty acid metabolic process|downregulation of fatty acid metabolic process|down regulation of fatty acid metabolic process|inhibition of fatty acid metabolic process|negative regulation of fatty acid metabolism Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving fatty acids. GO:0045929 positive regulation of juvenile hormone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045929 upregulation of juvenile hormone metabolic process|positive regulation of juvenile hormone metabolism|stimulation of juvenile hormone metabolic process|up-regulation of juvenile hormone metabolic process|activation of juvenile hormone metabolic process|up regulation of juvenile hormone metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone. GO:0045930 negative regulation of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045930 down-regulation of progression through mitotic cell cycle|negative regulation of mitotic cell cycle progression|downregulation of progression through mitotic cell cycle|down regulation of progression through mitotic cell cycle|inhibition of progression through mitotic cell cycle|negative regulation of progression through mitotic cell cycle Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle. GO:0045931 positive regulation of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045931 up regulation of progression through mitotic cell cycle|positive regulation of mitotic cell cycle progression|upregulation of progression through mitotic cell cycle|stimulation of progression through mitotic cell cycle|up-regulation of progression through mitotic cell cycle|positive regulation of progression through mitotic cell cycle|activation of progression through mitotic cell cycle Any process that activates or increases the rate or extent of progression through the mitotic cell cycle. GO:0045938 positive regulation of circadian sleep/wake cycle, sleep biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045938 upregulation of circadian sleep/wake cycle, sleep|up regulation of circadian sleep/wake cycle, sleep|activation of circadian sleep/wake cycle, sleep|stimulation of circadian sleep/wake cycle, sleep|positive regulation of sleep|up-regulation of circadian sleep/wake cycle, sleep Any process that activates or increases the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals. GO:0045939 negative regulation of steroid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045939 down regulation of steroid metabolic process|negative regulation of steroid metabolism|downregulation of steroid metabolic process|down-regulation of steroid metabolic process|inhibition of steroid metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving steroids. GO:0045936 negative regulation of phosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045936 down regulation of phosphate metabolic process|downregulation of phosphate metabolic process|negative regulation of phosphate metabolism|down-regulation of phosphate metabolic process|inhibition of phosphate metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates. GO:0045937 positive regulation of phosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045937 upregulation of phosphate metabolic process|up regulation of phosphate metabolic process|activation of phosphate metabolic process|stimulation of phosphate metabolic process|positive regulation of phosphate metabolism|up-regulation of phosphate metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates. GO:0045934 negative regulation of nucleobase-containing compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045934 downregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|down-regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism|inhibition of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|down regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process Any cellular process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. GO:0045935 positive regulation of nucleobase-containing compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|up regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|activation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|stimulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|up-regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism|upregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process Any cellular process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. GO:0045932 negative regulation of muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045932 down-regulation of muscle contraction|downregulation of muscle contraction|down regulation of muscle contraction|inhibition of muscle contraction Any process that stops, prevents, or reduces the frequency, rate or extent of muscle contraction. GO:0045933 positive regulation of muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045933 stimulation of muscle contraction|up-regulation of muscle contraction|activation of muscle contraction|up regulation of muscle contraction|upregulation of muscle contraction Any process that activates or increases the frequency, rate or extent of muscle contraction. CHEBI:606565 N-benzoylglycinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_606565 CHEBI:606564 prostaglandin E2(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_606564 GO:0045941 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045941 GO:0045942 negative regulation of phosphorus utilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045942 down-regulation of phosphorus utilization|downregulation of phosphorus utilization|down regulation of phosphorus utilization|inhibition of phosphorus utilization Any process that stops, prevents, or reduces the frequency, rate or extent of phosphorus utilization. OBO:GOCHE_37845 substance with growth hormone role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_37845 GO:0045940 positive regulation of steroid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045940 up-regulation of steroid metabolic process|upregulation of steroid metabolic process|positive regulation of steroid metabolism|up regulation of steroid metabolic process|activation of steroid metabolic process|stimulation of steroid metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving steroids. GO:0031391 Elg1 RFC-like complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031391 Elg1-RLC|RFC (Elg1)|Elg1-RFC A pentameric replication factor C (RLC) complex, which unloads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) from chromatin and has roles in telomere length regulation and other aspects of genome stability. In Saccharomyces the subunits are known as Elg1p, Rfc2p, Rfc3p, Rfc4p, and Rfc5p. GO:0045949 positive regulation of phosphorus utilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045949 stimulation of phosphorus utilization|up-regulation of phosphorus utilization|activation of phosphorus utilization|up regulation of phosphorus utilization|upregulation of phosphorus utilization Any process that activates or increases the frequency, rate or extent of phosphorus utilization. GO:0031392 regulation of prostaglandin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031392 regulation of prostaglandin anabolism|regulation of prostaglandin synthesis|regulation of prostaglandin formation|regulation of prostaglandin biosynthesis Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin. GO:0045947 negative regulation of translational initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045947 down-regulation of translational initiation|downregulation of translational initiation|down regulation of translational initiation|inhibition of translational initiation Any process that stops, prevents, or reduces the frequency, rate or extent of translational initiation. GO:0031390 Ctf18 RFC-like complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031390 RFC (Ctf18)|Ctf18-RFC|Ctf18-RLC A heptameric complex related to replication factor C, which loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA and plays a vital role in chromosome cohesion. In Saccharomyces the subunits are known as Ctf18p, Rfc2p, Rfc3p, Rfc4p, Rfc5p, Dcc1p, and Ctf8p. GO:0045948 positive regulation of translational initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045948 up regulation of translational initiation|upregulation of translational initiation|stimulation of translational initiation|up-regulation of translational initiation|activation of translational initiation Any process that activates or increases the frequency, rate or extent of translational initiation. GO:0045945 positive regulation of transcription by RNA polymerase III biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045945 positive regulation of transcription from RNA polymerase III promoter|up regulation of transcription from RNA polymerase III promoter|upregulation of transcription from RNA polymerase III promoter|positive regulation of transcription from Pol III promoter|stimulation of transcription from RNA polymerase III promoter|up-regulation of transcription from RNA polymerase III promoter|activation of transcription from RNA polymerase III promoter Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase III. GO:0045946 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045946 GO:0045943 positive regulation of transcription by RNA polymerase I biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045943 positive regulation of transcription from RNA polymerase I promoter|up regulation of transcription from RNA polymerase I promoter|upregulation of transcription from RNA polymerase I promoter|positive regulation of transcription from Pol I promoter|stimulation of transcription from RNA polymerase I promoter|up-regulation of transcription from RNA polymerase I promoter|activation of transcription from RNA polymerase I promoter Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase I. GO:0045944 positive regulation of transcription by RNA polymerase II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045944 up-regulation of global transcription from RNA polymerase II promoter|activation of transcription from RNA polymerase II promoter|stimulation of transcription from RNA polymerase II promoter|activation of global transcription from RNA polymerase II promoter|positive regulation of global transcription from Pol II promoter|up-regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter, global|positive regulation of transcription from Pol II promoter|up regulation of global transcription from RNA polymerase II promoter|upregulation of transcription from RNA polymerase II promoter|upregulation of global transcription from RNA polymerase II promoter|positive regulation of gene-specific transcription from RNA polymerase II promoter|stimulation of global transcription from RNA polymerase II promoter|up regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:0031399 regulation of protein modification process biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0031399 Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein. GO:0031397 negative regulation of protein ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031397 down-regulation of protein ubiquitination|downregulation of protein ubiquitination|down regulation of protein ubiquitination|inhibition of protein ubiquitination Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of ubiquitin groups to a protein. GO:0031398 positive regulation of protein ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031398 upregulation of protein ubiquitination|stimulation of protein ubiquitination|up-regulation of protein ubiquitination|activation of protein ubiquitination|up regulation of protein ubiquitination Any process that activates or increases the frequency, rate or extent of the addition of ubiquitin groups to a protein. GO:0031395 bursicon neuropeptide hormone complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031395 A neuropeptide hormone secreted by the central nervous system of insects that stimulates the tanning and sclerotization of the adult cuticle following eclosion. The active hormone consists of an obligate heterodimer of the alpha and beta subunits. GO:0031396 regulation of protein ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031396 Any process that modulates the frequency, rate or extent of the addition of ubiquitin groups to a protein. GO:0031393 negative regulation of prostaglandin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031393 down-regulation of prostaglandin biosynthetic process|negative regulation of prostaglandin biosynthesis|negative regulation of prostaglandin anabolism|downregulation of prostaglandin biosynthetic process|negative regulation of prostaglandin synthesis|down regulation of prostaglandin biosynthetic process|negative regulation of prostaglandin formation|inhibition of prostaglandin biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin. GO:0031394 positive regulation of prostaglandin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031394 up-regulation of prostaglandin biosynthetic process|activation of prostaglandin biosynthetic process|positive regulation of prostaglandin biosynthesis|positive regulation of prostaglandin anabolism|up regulation of prostaglandin biosynthetic process|positive regulation of prostaglandin synthesis|positive regulation of prostaglandin formation|upregulation of prostaglandin biosynthetic process|stimulation of prostaglandin biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin. GO:0045952 regulation of juvenile hormone catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045952 regulation of juvenile hormone degradation|regulation of juvenile hormone catabolism|regulation of juvenile hormone breakdown Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone. GO:0045953 negative regulation of natural killer cell mediated cytotoxicity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045953 negative regulation of natural killer cell mediated cell death|down regulation of natural killer cell mediated cytotoxicity|negative regulation of natural killer cell mediated cytolysis|downregulation of natural killer cell mediated cytotoxicity|negative regulation of NK cell mediated cytolysis|negative regulation of NK cell mediated cytotoxicity|negative regulation of NK cell mediated cell killing|down-regulation of natural killer cell mediated cytotoxicity|negative regulation of natural killer cell mediated cell killing|inhibition of natural killer cell mediated cytotoxicity|negative regulation of NK cell mediated cell death Any process that stops, prevents, or reduces the rate of natural killer mediated cytotoxicity. GO:0045950 negative regulation of mitotic recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045950 down regulation of mitotic recombination|downregulation of mitotic recombination|negative regulation of recombination within rDNA repeats|down-regulation of mitotic recombination|inhibition of mitotic recombination Any process that inhibits or decreases the rate of DNA recombination during mitosis. GO:0045951 positive regulation of mitotic recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045951 upregulation of mitotic recombination|up regulation of mitotic recombination|positive regulation of recombination within rDNA repeats|activation of mitotic recombination|stimulation of mitotic recombination|up-regulation of mitotic recombination Any process that activates or increases the frequency, rate or extent of DNA recombination during mitosis. GO:0070909 glutamate:gamma-aminobutyric acid antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070909 glutamate-gamma-aminobutyric acid antiporter activity|glutamate/gamma-aminobutyric acid antiporter activity|glutamate: GABA antiporter activity Catalysis of the reaction: glutamate(out) + gamma-aminobutyric acid(in) = glutamate(in) + gamma-aminobutyric acid(out). GO:0070907 histidine:histamine antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070907 histidine-histamine antiporter activity|histidine/histamine antiporter activity Catalysis of the reaction: histidine(out) + histamine(in) = histidine(in) + histamine(out). GO:0070908 tyrosine:tyramine antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070908 tyrosine/tyramine antiporter activity|tyrosine-tyramine antiporter activity Catalysis of the reaction: tyrosine(out) + tyramine(in) = tyrosine(in) + tyramine(out). GO:0070916 inositol phosphoceramide synthase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070916 IPC synthase complex A protein complex that possesses inositol phosphoceramide synthase activity and contains a catalytic subunit and a regulatory subunit (Aur1p and Kei1p, respectively, in Saccharomyces). GO:0031380 nuclear RNA-directed RNA polymerase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031380 Rdr1 complex|RDRC A complex required for RNAi mediated heterochromatin assembly. In S. pombe this contains RNA-directed RNA polymerase, a putative helicase and a protein containing a pap25 associated domain. GO:0070917 inositol phosphoceramide synthase regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070917 IPC synthase regulator activity Modulates the activity of inositol phosphoceramide synthase. GO:0031381 viral RNA-directed RNA polymerase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031381 A virus-specific protein complex that possesses RNA-dependent RNA polymerase activity and replicates the genome of an RNA virus. GO:0045958 positive regulation of complement activation, alternative pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045958 up regulation of complement activation, alternative pathway|upregulation of complement activation, alternative pathway|positive regulation of complement cascade, alternative pathway|stimulation of complement activation, alternative pathway|up-regulation of complement activation, alternative pathway|activation of complement activation, alternative pathway Any process that activates or increases the frequency, rate or extent of complement activation by the alternative pathway. GO:0070914 UV-damage excision repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070914 UV-damaged DNA endonuclease-dependent excision repair|UVDE-dependent excision repair|UVER|AER|alternative excision repair A DNA repair process that is initiated by an endonuclease that introduces a single-strand incision immediately 5' of a UV-induced damage site. UV-damage excision repair acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs). GO:0045959 negative regulation of complement activation, classical pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045959 negative regulation of complement cascade, classical pathway|down-regulation of complement activation, classical pathway|downregulation of complement activation, classical pathway|down regulation of complement activation, classical pathway|inhibition of complement activation, classical pathway Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the classical pathway. GO:0070915 lysophosphatidic acid receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070915 LPA receptor activity Combining with the phospholipid derivative lysophosphatidic acid, and transmitting the signal across the membrane by activating an associated G-protein. GO:0045956 positive regulation of calcium ion-dependent exocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045956 activation of calcium ion-dependent exocytosis|up regulation of calcium ion-dependent exocytosis|upregulation of calcium ion-dependent exocytosis|stimulation of calcium ion-dependent exocytosis|up-regulation of calcium ion-dependent exocytosis Any process that activates or increases the frequency, rate or extent of calcium ion-dependent exocytosis. GO:0070912 Ddb1-Ckn1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070912 A heterodimeric nucleotide-excision repair complex that is involved in transcription-coupled repair. The subunits are known as Ddb1 and Ckn1 in S. pombe; Ddb1 contains a motif called the DDB-box that interacts with adaptor proteins for DDB1/cullin 4 ubiquitin ligases. GO:0045957 negative regulation of complement activation, alternative pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045957 downregulation of complement activation, alternative pathway|down regulation of complement activation, alternative pathway|inhibition of complement activation, alternative pathway|negative regulation of complement cascade, alternative pathway|down-regulation of complement activation, alternative pathway Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the alternative pathway. GO:0070913 Ddb1-Wdr21 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070913 A heterodimeric nucleotide-excision repair complex that is involved in transcription-coupled repair. The subunits are known as Ddb1 and Wdr21 in S. pombe; Ddb1 contains a motif called the DDB-box that interacts with adaptor proteins for DDB1/cullin 4 ubiquitin ligases. GO:0045954 positive regulation of natural killer cell mediated cytotoxicity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045954 positive regulation of natural killer cell mediated cell death|upregulation of natural killer cell mediated cytotoxicity|positive regulation of NK cell mediated cytotoxicity|positive regulation of natural killer cell mediated cytolysis|positive regulation of NK cell mediated cell killing|up regulation of natural killer cell mediated cytotoxicity|activation of natural killer cell mediated cytotoxicity|positive regulation of NK cell mediated cytolysis|positive regulation of natural killer cell mediated cell killing|stimulation of natural killer cell mediated cytotoxicity|up-regulation of natural killer cell mediated cytotoxicity|positive regulation of NK cell mediated cell death Any process that activates or increases the frequency, rate or extent of natural killer cell mediated cytotoxicity. GO:0070910 cell wall macromolecule catabolic process involved in cell wall disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070910 The chemical reactions and pathways that result in the breakdown of macromolecules that form part of a cell wall, and contributes to the breakdown of the cell wall. GO:0070911 global genome nucleotide-excision repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070911 GG-NER|global genomic repair|global genome NER|global genomic nucleotide-excision repair|GGR The nucleotide-excision repair process in which DNA lesions are removed from nontranscribed strands and from transcriptionally silent regions over the entire genome. GO:0045955 negative regulation of calcium ion-dependent exocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045955 down-regulation of calcium ion-dependent exocytosis|downregulation of calcium ion-dependent exocytosis|down regulation of calcium ion-dependent exocytosis|inhibition of calcium ion-dependent exocytosis Any process that stops, prevents, or reduces the frequency, rate or extent of calcium ion-dependent exocytosis. GO:0031388 organic acid phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031388 The process of introducing one or more phosphate groups into an organic acid. GO:0031389 Rad17 RFC-like complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031389 Rad17-RFC|Rad17-RLC|Rad24p RFC-like complex|RFC (Rad17) A pentameric protein complex related to replication factor C, which loads a trimeric complex of checkpoint proteins (known as the checkpoint clamp or 9-1-1 complex) onto DNA at damage sites; functions in DNA damage cell cycle checkpoints. In Schizosaccharomyces pombe the subunits are known as Rad17, Rfc2, Rfc3, Rfc4, and Rfc5, while in Saccharomyces cerevisiae the subunits are known as Rad24p, Rfc2p, Rfc3p, Rfc4p, and Rfc5p. GO:0031386 protein tag biolink:MolecularActivity go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0031386 ubiquitin-like protein modifier|protein tagging activity|covalent modifier|ubiquitin A molecular function exhibited by a protein that is covalently attached (AKA tagged or conjugated) to another protein where it acts as a marker, recognized by the cellular apparatus to target the tagged protein for some cellular process such as modification, sequestration, transport or degradation. GO:0031387 MPF complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031387 A complex consisting of a Cdc2-class (also known as Cdc28) cyclin-dependent kinase and an M-phase cyclin such as S. pombe Cdc13. The MPF complex phosphorylates and activates the anaphase promoting complex (APC). GO:0031384 regulation of initiation of mating projection growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031384 Any process that modulates the frequency, rate, or extent of the start of mating projection formation by unicellular fungi. GO:0031385 regulation of termination of mating projection growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031385 Any process that modulates the frequency, rate, or extent of the end of mating projection formation by unicellular fungi. GO:0031382 mating projection formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031382 mating projection assembly|shmooing|mating projection biogenesis The aggregation, arrangement and bonding together of a set of components to form a cell projection in response to mating pheromone. This process is observed in unicellular fungi. GO:0031383 regulation of mating projection assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031383 regulation of mating projection biogenesis Any process that modulates the frequency, rate, or extent of mating projection formation by unicellular fungi. GO:0031379 RNA-directed RNA polymerase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031379 A protein complex that possesses RNA-directed RNA polymerase activity. GO:0045963 negative regulation of dopamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045963 down-regulation of dopamine metabolic process|downregulation of dopamine metabolic process|down regulation of dopamine metabolic process|inhibition of dopamine metabolic process|negative regulation of dopamine metabolism Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving dopamine. GO:0045964 positive regulation of dopamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045964 stimulation of dopamine metabolic process|activation of dopamine metabolic process|up-regulation of dopamine metabolic process|up regulation of dopamine metabolic process|upregulation of dopamine metabolic process|positive regulation of dopamine metabolism Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving dopamine. GO:0045961 negative regulation of development, heterochronic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045961 down-regulation of development, heterochronic|downregulation of development, heterochronic|down regulation of development, heterochronic|inhibition of development, heterochronic Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and decreases the rate at which this time point is reached. GO:0045962 positive regulation of development, heterochronic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045962 upregulation of development, heterochronic|stimulation of development, heterochronic|activation of development, heterochronic|up-regulation of development, heterochronic|up regulation of development, heterochronic Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and increases the rate at which this time point is reached. GO:0045960 positive regulation of complement activation, classical pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045960 upregulation of complement activation, classical pathway|positive regulation of complement cascade, classical pathway|stimulation of complement activation, classical pathway|activation of complement activation, classical pathway|up-regulation of complement activation, classical pathway|up regulation of complement activation, classical pathway Any process that activates or increases the frequency, rate or extent of complement activation by the classical pathway. GO:0070905 serine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070905 Ser binding Interacting selectively and non-covalently with 2-amino-3-hydroxypropanoic acid. GO:0070906 aspartate:alanine antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070906 RHEA:33139 aspartate-alanine antiporter activity|aspartate/alanine antiporter activity Catalysis of the reaction: aspartate(out) + alanine(in) = aspartate(in) + alanine(out). GO:0031370 eukaryotic initiation factor 4G binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031370 eIF4G binding Interacting selectively and non-covalently with eukaryotic initiation factor 4G, a polypeptide factor involved in the initiation of ribosome-mediated translation. GO:0045969 positive regulation of juvenile hormone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045969 stimulation of juvenile hormone biosynthetic process|positive regulation of juvenile hormone formation|up-regulation of juvenile hormone biosynthetic process|upregulation of juvenile hormone biosynthetic process|positive regulation of juvenile hormone anabolism|up regulation of juvenile hormone biosynthetic process|activation of juvenile hormone biosynthetic process|positive regulation of juvenile hormone biosynthesis|positive regulation of juvenile hormone synthesis Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone. GO:0070903 mitochondrial tRNA thio-modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070903 The addition a sulfur atom to a nucleotide in a mitochondrial tRNA molecule. GO:0070904 transepithelial L-ascorbic acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070904 transepithelial L-ascorbate transport|transepithelial vitamin C transport The directed movement of L-ascorbic acid from one side of an epithelium to the other. GO:0070901 mitochondrial tRNA methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070901 The posttranscriptional addition of methyl groups to specific residues in a mitochondrial tRNA molecule. GO:0045967 negative regulation of growth rate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045967 down-regulation of growth rate|inhibition of growth rate|down regulation of growth rate|downregulation of growth rate Any process that reduces the rate of growth of all or part of an organism. GO:0045968 negative regulation of juvenile hormone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045968 negative regulation of juvenile hormone biosynthesis|down-regulation of juvenile hormone biosynthetic process|inhibition of juvenile hormone biosynthetic process|down regulation of juvenile hormone biosynthetic process|negative regulation of juvenile hormone anabolism|downregulation of juvenile hormone biosynthetic process|negative regulation of juvenile hormone synthesis|negative regulation of juvenile hormone formation Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone. GO:0070902 mitochondrial tRNA pseudouridine synthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070902 The intramolecular conversion of uridine to pseudouridine in a mitochondrial tRNA molecule. GO:0045965 negative regulation of ecdysteroid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045965 down regulation of ecdysteroid metabolic process|downregulation of ecdysteroid metabolic process|down-regulation of ecdysteroid metabolic process|inhibition of ecdysteroid metabolic process|negative regulation of ecdysteroid metabolism Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving ecdysteroids. GO:0045966 positive regulation of ecdysteroid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045966 positive regulation of ecdysteroid metabolism|up regulation of ecdysteroid metabolic process|activation of ecdysteroid metabolic process|stimulation of ecdysteroid metabolic process|up-regulation of ecdysteroid metabolic process|upregulation of ecdysteroid metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving ecdysteroids. GO:0070900 mitochondrial tRNA modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070900 The covalent alteration of one or more nucleotides within a mitochondrial tRNA molecule to produce a mitochondrial tRNA molecule with a sequence that differs from that coded genetically. GO:0031377 obsolete mitochondrial type II fatty acid synthase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031377 mitochondrial type II fatty acid synthase complex|mitochondrial type II FAS complex OBSOLETE. A fatty acid synthase complex in which each polypeptide chain catalyzes a single activity, located in the mitochondrion. GO:0031378 obsolete plastid type II fatty acid synthase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031378 plastid type II FAS complex|plastid type II fatty acid synthase complex OBSOLETE. A fatty acid synthase complex in which each polypeptide chain catalyzes a single activity, located in a plastid. GO:0031375 obsolete type II fatty acid synthase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031375 type II FAS complex|type II fatty acid synthase complex|type II fatty acid synthase|type II FAS OBSOLETE. A fatty acid synthase complex in which each polypeptide chain catalyzes a single activity. GO:0031376 obsolete cytosolic type II fatty acid synthase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031376 cytosolic type II fatty acid synthase complex|cytosolic type II FAS complex OBSOLETE. A fatty acid synthase complex in which each polypeptide chain catalyzes a single activity, located in the cytosol. GO:0031373 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031373 GO:0031374 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031374 GO:0031371 ubiquitin conjugating enzyme complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0031371 E2 complex Any complex that possesses ubiquitin conjugating enzyme activity. GO:0031372 UBC13-MMS2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031372 A heterodimeric ubiquitin conjugating enzyme complex that catalyzes assembly of K63-linked polyubiquitin chains, which act as a signal to promote error-free DNA postreplication repair; in Saccharomyces the complex comprises Ubc13p and Mms2p. GO:0031368 obsolete Pro-X metallocarboxypeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031368 EC:3.4.17.16 microsomal carboxypeptidase activity|carboxypeptidase P activity|membrane Pro-X carboxypeptidase activity|membrane Pro-Xaa carboxypeptidase|Pro-X metallocarboxypeptidase activity OBSOLETE. Catalysis of the cleavage of a Pro-Xaa bond by a metallopeptidase mechanism to release a C-terminal amino acid. GO:0031369 translation initiation factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031369 Interacting selectively and non-covalently with a translation initiation factor, any polypeptide factor involved in the initiation of ribosome-mediated translation. GO:0045974 regulation of translation, ncRNA-mediated biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045974 Any process, mediated by small non-coding RNAs, that modulates the frequency, rate or extent that mRNAs are effectively translated into protein. GO:0045975 positive regulation of translation, ncRNA-mediated biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045975 up regulation of mRNA translation, ncRNA-mediated|upregulation of mRNA translation, ncRNA-mediated|stimulation of mRNA translation, ncRNA-mediated|up-regulation of mRNA translation, ncRNA-mediated|activation of mRNA translation, ncRNA-mediated Any process, mediated by small non-coding RNAs, that activates or increases the rate that mRNAs are effectively translated into protein. GO:0045972 negative regulation of juvenile hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045972 down-regulation of juvenile hormone secretion|downregulation of juvenile hormone secretion|down regulation of juvenile hormone secretion|inhibition of juvenile hormone secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of juvenile hormone. GO:0045973 positive regulation of juvenile hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045973 up regulation of juvenile hormone secretion|upregulation of juvenile hormone secretion|stimulation of juvenile hormone secretion|up-regulation of juvenile hormone secretion|activation of juvenile hormone secretion Any process that activates or increases the frequency, rate or extent of the regulated release of juvenile hormone. GO:0045970 negative regulation of juvenile hormone catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045970 downregulation of juvenile hormone catabolic process|down regulation of juvenile hormone catabolic process|inhibition of juvenile hormone catabolic process|negative regulation of juvenile hormone catabolism|negative regulation of juvenile hormone degradation|negative regulation of juvenile hormone breakdown|down-regulation of juvenile hormone catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone. GO:0045971 positive regulation of juvenile hormone catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045971 up regulation of juvenile hormone catabolic process|positive regulation of juvenile hormone catabolism|upregulation of juvenile hormone catabolic process|stimulation of juvenile hormone catabolic process|up-regulation of juvenile hormone catabolic process|activation of juvenile hormone catabolic process|positive regulation of juvenile hormone degradation|positive regulation of juvenile hormone breakdown Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone. GO:0070929 trans-translation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070929 A translational elongation process in which transfer of a translating ribosome from one mRNA to another RNA template takes place. Trans-translation occurs during tmRNA release of stalled ribosomes. GO:0070938 contractile ring biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070938 constriction ring|cytokinetic ring A cytoskeletal structure composed of filamentous protein that forms beneath the membrane of many cells or organelles, in the plane of cell or organelle division. Ring contraction is associated with centripetal growth of the membrane that divides the cytoplasm of the two daughter cells or organelles. GO:0070939 Dsl1/NZR complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070939 CATCHR family complex|Dsl1p complex|NZR complex A multisubunit tethering complex, i.e. a protein complex involved in mediating the initial interaction between vesicles and the membranes with which they fuse, that is involved in trafficking from the Golgi apparatus to the ER. In Saccharomyces cerevisiae the Dsl1p complex contains Dsl1p, Tip20p, and Sec39p. GO:0070936 protein K48-linked ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070936 protein K48-linked polyubiquitination A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation. GO:0070937 CRD-mediated mRNA stability complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070937 coding-region instability determinant -mediated mRNA stability complex|coding-region determinant of instability-mediated mRNA stability complex A protein complex that binds to, and promotes stabilization of, mRNA molecules containing the coding region instability determinant (CRD). In human, it may consist of IGF2BP1, HNRNPU, SYNCRIP/HNRNPQ, YBX1, and DHX9. GO:0045978 negative regulation of nucleoside metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045978 downregulation of nucleoside metabolic process|down regulation of nucleoside metabolic process|inhibition of nucleoside metabolic process|negative regulation of nucleoside metabolism|down-regulation of nucleoside metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleosides. GO:0070934 CRD-mediated mRNA stabilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070934 coding region determinant-mediated mRNA stabilization An mRNA stabilization process in which one or more RNA-binding proteins associate with a sequence in the open reading frame called the coding region instability determinant (CRD). GO:0045979 positive regulation of nucleoside metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045979 up regulation of nucleoside metabolic process|upregulation of nucleoside metabolic process|positive regulation of nucleoside metabolism|stimulation of nucleoside metabolic process|up-regulation of nucleoside metabolic process|activation of nucleoside metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleosides. GO:0070935 3'-UTR-mediated mRNA stabilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070935 3'-untranslated region-mediated mRNA stabilization An mRNA stabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA. GO:0070932 histone H3 deacetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070932 The modification of histone H3 by the removal of one or more acetyl groups. GO:0045976 negative regulation of mitotic cell cycle, embryonic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045976 down regulation of progression through embryonic mitotic cell cycle|inhibition of progression through embryonic mitotic cell cycle|negative regulation of progression through embryonic mitotic cell cycle|negative regulation of embryonic mitotic cell cycle|down-regulation of progression through embryonic mitotic cell cycle|negative regulation of embryonic mitotic cell cycle progression|downregulation of progression through embryonic mitotic cell cycle Any process that stops, prevents or reduces the rate or extent of progression through the embryonic mitotic cell cycle. GO:0070933 histone H4 deacetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070933 The modification of histone H4 by the removal of one or more acetyl groups. GO:0045977 positive regulation of mitotic cell cycle, embryonic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045977 upregulation of mitotic cell cycle, embryonic|up regulation of mitotic cell cycle, embryonic|positive regulation of progression through embryonic mitotic cell cycle|positive regulation of embryonic mitotic cell cycle|activation of mitotic cell cycle, embryonic|stimulation of mitotic cell cycle, embryonic|up-regulation of mitotic cell cycle, embryonic|positive regulation of embryonic mitotic cell cycle progression Any process that activates or increases the frequency, rate or extent of progression through the embryonic mitotic cell cycle. GO:0070930 trans-translation-dependent protein tagging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070930 protein modification by trans-translation|cotranslational protein tagging|co-translational protein tagging A protein modification process in which a polypeptide is added to a nascent polypeptide cotranslationally by trans-translation. GO:0031366 N-terminal peptidyl-asparagine deamination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031366 The removal of an amino group from the side chain of an N-terminal asparagine residue of a protein. GO:0070931 Golgi-associated vesicle lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070931 The volume enclosed by the membrane of a Golgi-associated vesicle. GO:0031367 N-terminal peptidyl-glutamine deamination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031367 The removal of an amino group from the side chain of an N-terminal glutamine residue of a protein. GO:0031364 N-terminal protein amino acid deamination, from side chain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031364 The removal of an amino group from the side chain of an N-terminal asparagine or glutamine residue of a protein. GO:0031365 N-terminal protein amino acid modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031365 peptide or protein amino-terminal blocking|peptide/protein amino-terminal blocking The alteration of the N-terminal amino acid residue in a protein. GO:0031362 anchored component of external side of plasma membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031362 anchored to external leaflet of plasma membrane|anchored to external side of plasma membrane The component of the plasma membrane consisting of the gene products that are tethered to the external side of the membrane only by a covalently attached anchor, such as a lipid group embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. GO:0031363 N-terminal protein amino acid deamination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031363 The removal of an amino group from the N-terminal amino acid residue of a protein. GO:0031360 intrinsic component of thylakoid membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031360 intrinsic to thylakoid membrane The component of the thylakoid membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0031361 integral component of thylakoid membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031361 integral to thylakoid membrane The component of the thylakoid membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0031359 integral component of chloroplast outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031359 integral to chloroplast outer membrane The component of the chloroplast outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0031357 integral component of chloroplast inner membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031357 integral to chloroplast inner membrane The component of the chloroplast inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0031358 intrinsic component of chloroplast outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031358 intrinsic to chloroplast outer membrane The component of the chloroplast outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0045985 positive regulation of pyrimidine nucleobase metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045985 up-regulation of pyrimidine base metabolic process|upregulation of pyrimidine base metabolic process|positive regulation of pyrimidine base metabolism|up regulation of pyrimidine base metabolic process|activation of pyrimidine base metabolic process|positive regulation of pyrimidine base metabolic process|stimulation of pyrimidine base metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine nucleobases. GO:0045986 negative regulation of smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045986 inhibition of smooth muscle contraction|down regulation of smooth muscle contraction|downregulation of smooth muscle contraction|smooth muscle relaxation|down-regulation of smooth muscle contraction Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle contraction. GO:0045983 positive regulation of purine nucleobase metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045983 upregulation of purine base metabolic process|up regulation of purine base metabolic process|positive regulation of purine base metabolic process|activation of purine base metabolic process|positive regulation of purine base metabolism|stimulation of purine base metabolic process|up-regulation of purine base metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving purine bases. GO:0045984 negative regulation of pyrimidine nucleobase metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045984 inhibition of pyrimidine base metabolic process|negative regulation of pyrimidine base metabolism|down regulation of pyrimidine base metabolic process|downregulation of pyrimidine base metabolic process|down-regulation of pyrimidine base metabolic process|negative regulation of pyrimidine base metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine nucleobases. GO:0045981 positive regulation of nucleotide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045981 up regulation of nucleotide metabolic process|upregulation of nucleotide metabolic process|positive regulation of nucleotide metabolism|stimulation of nucleotide metabolic process|up-regulation of nucleotide metabolic process|activation of nucleotide metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleotides. GO:0045982 negative regulation of purine nucleobase metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045982 down regulation of purine base metabolic process|downregulation of purine base metabolic process|negative regulation of purine base metabolism|down-regulation of purine base metabolic process|negative regulation of purine base metabolic process|inhibition of purine base metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving purine nucleobases. GO:0070918 production of small RNA involved in gene silencing by RNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070918 gene silencing by RNA, production of small RNA|gene silencing by RNA, production of guide RNA The process in which a double-stranded RNA precursor is processed into short (20-30 nt) fragments. RNA cleavage is catalyzed by a Dicer endonuclease. GO:0045980 negative regulation of nucleotide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045980 down-regulation of nucleotide metabolic process|downregulation of nucleotide metabolic process|down regulation of nucleotide metabolic process|inhibition of nucleotide metabolic process|negative regulation of nucleotide metabolism Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleotides. GO:0070919 production of siRNA involved in chromatin silencing by small RNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070919 chromatin silencing by small RNA, production of siRNA|production of guide RNAs involved in chromatin silencing by small RNA|chromatin silencing by small RNA, production of guide RNAs Cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of chromatin silencing by small RNA. GO:0070927 negative regulation of ATP:ADP antiporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070927 inhibition of ATP:ADP antiporter activity|down regulation of ATP:ADP antiporter activity|downregulation of ATP:ADP antiporter activity|down-regulation of ATP:ADP antiporter activity Any process that stops or reduces the activity of an ATP:ADP antiporter. GO:0070928 regulation of mRNA stability, ncRNA-mediated biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070928 ncRNA-mediated regulation of mRNA stability|regulation of mRNA stability, non-coding RNA-mediated Any process, mediated by small non-coding RNAs, that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs. GO:0070925 organelle assembly biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0070925 The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. GO:0070926 regulation of ATP:ADP antiporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070926 Any process that modulates the activity of an ATP:ADP antiporter. GO:0070923 siRNA loading onto RISC involved in chromatin silencing by small RNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070923 chromatin silencing by small RNA, siRNA loading onto RISC The process in which a single-stranded small RNA associates with the RNA-initiated silencing complex (RISC); occurs as part of a process of chromatin silencing by small RNA. GO:0045989 positive regulation of striated muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045989 up-regulation of striated muscle contraction|upregulation of striated muscle contraction|up regulation of striated muscle contraction|activation of striated muscle contraction|stimulation of striated muscle contraction Any process that activates or increases the frequency, rate or extent of striated muscle contraction. GO:0070924 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0070924 GO:0070921 regulation of production of siRNA involved in chromatin silencing by small RNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070921 regulation of chromatin silencing by small RNA, production of siRNA Any process that modulates the frequency, rate or extent of the production of siRNA, the cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of chromatin silencing by small RNA. GO:0045987 positive regulation of smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045987 up-regulation of smooth muscle contraction|upregulation of smooth muscle contraction|up regulation of smooth muscle contraction|activation of smooth muscle contraction|stimulation of smooth muscle contraction Any process that activates or increases the frequency, rate or extent of smooth muscle contraction. GO:0045988 negative regulation of striated muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045988 inhibition of striated muscle contraction|down regulation of striated muscle contraction|downregulation of striated muscle contraction|down-regulation of striated muscle contraction Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle contraction. GO:0070922 small RNA loading onto RISC biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070922 RISC assembly|gene silencing by RNA, small RNA loading onto RISC The process in which a single-stranded small RNA associates with the RNA-initiated silencing complex (RISC); occurs as part of a process of gene silencing by small RNA. GO:0031355 integral component of plastid outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031355 integral to plastid outer membrane The component of the plastid outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0070920 regulation of production of small RNA involved in gene silencing by RNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070920 regulation of gene silencing by RNA, production of small RNA|regulation of gene silencing by RNA, production of guide RNA Any process that modulates the frequency, rate or extent of the production of small RNA involved in gene silencing by RNA. GO:0031356 intrinsic component of chloroplast inner membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031356 intrinsic to chloroplast inner membrane The component of the chloroplast inner membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0031353 integral component of plastid inner membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031353 integral to plastid inner membrane The component of the plastid inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0031354 intrinsic component of plastid outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031354 intrinsic to plastid outer membrane The component of the plastid outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0031351 integral component of plastid membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031351 integral to plastid membrane The component of the plastid membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0031352 intrinsic component of plastid inner membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031352 intrinsic to plastid inner membrane The component of the plastid inner membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0031350 intrinsic component of plastid membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031350 intrinsic to plastid membrane The component of the plastid membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. CHEBI:22743 benzyl alcohols biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22743 CHEBI:22744 benzyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_22744 CHEBI:22748 benzyl 2-methyl-3-hydroxybutanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_22748 CHEBI:22746 2-benzylsuccinyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22746 CHEBI:22750 benzylisoquinoline alkaloid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22750 CHEBI:22754 berberine alkaloid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22754 CHEBI:46700 benzoxazole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46700 CHEBI:46701 pyrrolidinemonocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46701 CHEBI:46702 (-)-geosmin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46702 CHEBI:46703 geosmin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46703 CHEBI:46705 (+)-geosmin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46705 CHEBI:22720 benzodiazepine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22720 CHEBI:22726 benzophenones biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22726 CHEBI:22723 benzoic acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22723 CHEBI:22729 benzoquinones biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22729 CHEBI:22727 benzopyran biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22727 CHEBI:22728 benzopyrrole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22728 CHEBI:22730 benzosemiquinones biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22730 CHEBI:22731 3-oxo-3-phenylpropionate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_22731 CHEBI:22736 benzoyl-CoAs biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22736 CHEBI:71711 phosphatidylethanolamine 32:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71711 CHEBI:71712 phosphatidylethanolamine 32:1 zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71712 CHEBI:71713 phosphatidylethanolamine 32:2 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71713 CHEBI:71718 phosphatidylethanolamine 34:0 zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71718 CHEBI:71719 9-ribosyl-trans-zeatin 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71719 CHEBI:4712 doxercalciferol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_4712 CHEBI:22702 benzamides biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22702 CHEBI:22707 benzenetriol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22707 CHEBI:22706 benzenetetrol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22706 CHEBI:71720 phosphatidylethanolamine 34:1 zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71720 CHEBI:71721 phosphatidylethanolamine 34:2 zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71721 CHEBI:71727 phosphatidylethanolamine 36:1 zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71727 CHEBI:71728 phosphatidylethanolamine 36:2 zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71728 CHEBI:71729 phosphatidylethanolamine 36:3 zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71729 CHEBI:22715 benzimidazoles biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22715 CHEBI:22712 benzenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22712 CHEBI:22713 arenesulfonate oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22713 CHEBI:22718 benzoates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22718 CHEBI:71730 phosphatidylethanolamine 36:4 zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71730 CHEBI:71737 phosphatidylethanolamine 38:4 zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71737 CHEBI:71738 phosphatidylethanolamine 38:5 zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71738 CHEBI:71739 phosphatidylethanolamine 38:6 zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71739 CHEBI:71746 phosphatidylethanolamine 40:6 zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71746 CHEBI:4705 double-stranded DNA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_4705 GO:0045905 positive regulation of translational termination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045905 activation of translational termination|stimulation of translational termination|up-regulation of translational termination|upregulation of translational termination|up regulation of translational termination Any process that activates or increases the frequency, rate or extent of translational termination. GO:0045906 negative regulation of vasoconstriction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045906 down-regulation of vasoconstriction|downregulation of vasoconstriction|down regulation of vasoconstriction|inhibition of vasoconstriction Any process that stops, prevents, or reduces the frequency, rate or extent of vasoconstriction. GO:0045903 positive regulation of translational fidelity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045903 up regulation of translational fidelity|upregulation of translational fidelity|stimulation of translational fidelity|up-regulation of translational fidelity|activation of translational fidelity Any process that increases the ability of the translational apparatus to interpret the genetic code. GO:0045904 negative regulation of translational termination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045904 down-regulation of translational termination|inhibition of translational termination|down regulation of translational termination|downregulation of translational termination Any process that stops, prevents, or reduces the frequency, rate or extent of translational termination. GO:0045901 positive regulation of translational elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045901 upregulation of translational elongation|stimulation of translational elongation|activation of translational elongation|up-regulation of translational elongation|up regulation of translational elongation Any process that activates or increases the frequency, rate or extent of translational elongation. GO:0045902 negative regulation of translational fidelity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045902 downregulation of translational fidelity|down regulation of translational fidelity|inhibition of translational fidelity|down-regulation of translational fidelity Any process that decreases the ability of the translational apparatus to interpret the genetic code. GO:0045900 negative regulation of translational elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045900 down-regulation of translational elongation|downregulation of translational elongation|down regulation of translational elongation|inhibition of translational elongation Any process that stops, prevents, or reduces the frequency, rate or extent of translational elongation. GO:0045909 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045909 GO:0045907 positive regulation of vasoconstriction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045907 activation of vasoconstriction|up regulation of vasoconstriction|upregulation of vasoconstriction|stimulation of vasoconstriction|up-regulation of vasoconstriction Any process that activates or increases the frequency, rate or extent of vasoconstriction. GO:0045908 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045908 GO:0006308 DNA catabolic process biolink:BiologicalProcess go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0006308 DNA degradation|DNA catabolism|DNA breakdown The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one. GO:0006309 apoptotic DNA fragmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006309 DNA catabolic process during apoptosis|DNA catabolism during apoptosis|endonucleolytic DNA catabolic process involved in apoptosis|chromatinolysis|DNA fragmentation|DNA fragmentation involved in apoptotic nuclear change The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of about 50 kbp followed by cleavage between nucleosomes to yield 200 bp fragments. GO:0006306 DNA methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006306 Wikipedia:DNA_methylation The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine. GO:0006307 DNA dealkylation involved in DNA repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006307 The repair of alkylation damage, e.g. the removal of the alkyl group at the O6-position of guanine by O6-alkylguanine-DNA alkyltransferase (AGT). GO:0006304 DNA modification biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0006304 The covalent alteration of one or more nucleotide sites in DNA, resulting in a change in its properties. GO:0006305 DNA alkylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006305 The addition of alkyl groups to many positions on all four bases of DNA. Alkylating agents can also modify the bases of incoming nucleotides in the course of DNA synthesis. GO:0006302 double-strand break repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006302 The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix. GO:0006303 double-strand break repair via nonhomologous end joining biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006303 NHEJ The repair of a double-strand break in DNA in which the two broken ends are rejoined with little or no sequence complementarity. Information at the DNA ends may be lost due to the modification of broken DNA ends. This term covers instances of separate pathways, called classical (or canonical) and alternative nonhomologous end joining (C-NHEJ and A-NHEJ). These in turn may further branch into sub-pathways, but evidence is still unclear. GO:0021940 positive regulation of cerebellar granule cell precursor proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021940 upregulation of granule cell precursor proliferation|stimulation of granule cell precursor proliferation|up-regulation of granule cell precursor proliferation|activation of granule cell precursor proliferation|up regulation of granule cell precursor proliferation The process that activates or increases the rate or extent of granule cell precursor proliferation. GO:0006300 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006300 GO:0006301 postreplication repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006301 Wikipedia:Postreplication_repair postreplication DNA repair The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication. Includes pathways that remove replication-blocking lesions in conjunction with DNA replication. GO:0021949 brainstem precerebellar neuron precursor migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021949 The early migration of a precerebellar neuronal precursor in which a cell move from the rhombic lip, orthogonal to the direction of radial migration and ultimately reside in the brainstem. GO:0021941 negative regulation of cerebellar granule cell precursor proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021941 down regulation of granule cell precursor proliferation|inhibition of granule cell precursor proliferation|down-regulation of granule cell precursor proliferation|downregulation of granule cell precursor proliferation The process that stops, prevents or reduces the rate or extent of granule cell precursor proliferation. GO:0021942 radial glia guided migration of Purkinje cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021942 The migration of postmitotic a Purkinje cell along radial glial cells from the ventricular zone to the Purkinje cell layer. GO:0021943 formation of radial glial scaffolds biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021943 Bergmann fiber biosynthesis|Bergmann fiber formation The formation of scaffolds from a radial glial cell. The scaffolds are used as a substrate for the radial migration of cells. GO:0021944 neuronal-glial interaction involved in hindbrain glial-mediated radial cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021944 The changes in adhesion between a neuronal cell and a glial cell as a component of the process of hindbrain glial-mediated radial cell migration. GO:0021945 positive regulation of cerebellar granule cell migration by calcium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021945 calcium-mediated up regulation of granule cell migration|calcium-mediated upregulation of granule cell migration|calcium-mediated stimulation of granule cell migration|calcium-mediated activation of granule cell migration|calcium-mediated up-regulation of granule cell migration|calcium-mediated positive regulation of granule cell migration The process that increases the extent of granule cell motility using intracellular calcium signaling mechanisms during radial migration. GO:0021946 deep nuclear neuron cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021946 The directed movement of a deep nuclear neuron from the ventricular zone to the deep hindbrain nuclei. GO:0021947 outward migration of deep nuclear neurons biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021947 The directed movement of a deep nuclear neuron from their ventrolateral origin to a rostrodorsal region of the cerebellar plate. GO:0021948 inward migration of deep nuclear neurons biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021948 The directed movement of a deep nuclear neuron from the rostrodorsal region of the cerebellar plate to their final more ventral position. GO:0006319 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006319 GO:0006317 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006317 GO:0006318 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006318 GO:0006315 homing of group II introns biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006315 Lateral transfer of a group II intron to a homologous allele that lacks the intron, mediated by a site-specific endonuclease encoded within the mobile intron; group II introns are self-splicing introns with a conserved secondary structure. CHEBI:46787 solvent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46787 GO:0006316 movement of group I intron biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006316 Lateral transfer of a group I intron to a homologous allele that lacks the intron, mediated by a site-specific endonuclease encoded within the mobile intron; group I introns are self-splicing introns that use guanosine as a cofactor in the splicing reaction. GO:0006313 transposition, DNA-mediated biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006313 Class II transposition|Tc1/mariner transposition|P-element transposition|P-element excision|DNA transposition|Tc3 transposition Any process involved in a type of transpositional recombination which occurs via a DNA intermediate. GO:0006314 intron homing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006314 Lateral transfer of an intron to a homologous allele that lacks the intron, mediated by a site-specific endonuclease encoded within the mobile intron. GO:0006311 meiotic gene conversion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006311 gene conversion without reciprocal crossover The cell cycle process in which genetic information is transferred from one helix to another. It often occurs in association with general genetic recombination events, and is believed to be a straightforward consequence of the mechanisms of general recombination and DNA repair. For example, meiosis might yield three copies of the maternal version of an allele and only one copy of the paternal allele, indicating that one of the two copies of the paternal allele has been changed to a copy of the maternal allele. GO:0006312 mitotic recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006312 Wikipedia:Mitotic_crossover The exchange, reciprocal or nonreciprocal, of genetic material between one DNA molecule and a homologous region of DNA that occurs during mitotic cell cycles. GO:0006310 DNA recombination biolink:BiologicalProcess go-plus goslim_pombe|goslim_yeast|goslim_drosophila http://purl.obolibrary.org/obo/GO_0006310 Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction. GO:0021938 smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021938 hh signaling pathway involved in regulation of granule cell precursor cell proliferation|hedgehog signaling pathway involved in regulation of granule cell precursor cell proliferation|smoothened signalling pathway in regulation of granule cell precursor cell proliferation The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened in cerebellar granule cells that contributes to the regulation of proliferation of the cells. GO:0021939 extracellular matrix-granule cell signaling involved in regulation of granule cell precursor proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021939 extracellular matrix-granule cell signalling involved in regulation of granule cell precursor proliferation The process that mediates the transfer of information from the extracellular matrix to granule cell precursors resulting in a decrease in rate of granule cell precursor cell proliferation. CHEBI:32154 octadecan-1-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32154 CHEBI:4767 Elastin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_4767 GO:0021930 cerebellar granule cell precursor proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021930 The multiplication or reproduction of neuroblasts that will give rise to granule cells. A granule cell is a glutamatergic interneuron found in the cerebellar cortex. GO:0021931 rostral hindbrain neuronal precursor cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021931 The multiplication or reproduction of neuroblasts that will give rise to neurons of the lateral pontine nucleus and the locus ceruleus. GO:0021932 hindbrain radial glia guided cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021932 The radially directed movement of a cell along radial glial cells in the hindbrain. Radial migration refers to a directed movement from the internal ventricular area to the outer surface of the hindbrain. GO:0021933 radial glia guided migration of cerebellar granule cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021933 The inward migration of postmitotic granule cells along a radial glial cell from the external granule layer to the internal granule cell layer. GO:0021934 hindbrain tangential cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021934 hindbrain neurophilic migration The migration of a cell in the hindbrain in which cells move orthogonal to the direction of radial migration. GO:0021935 cerebellar granule cell precursor tangential migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021935 The early migration of granule cell precursors in which cells move orthogonal to the direction of radial migration and ultimately cover the superficial zone of the cerebellar primordium. GO:0021936 regulation of cerebellar granule cell precursor proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021936 The process that modulates the frequency, rate or extent of granule cell precursor proliferation. GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021937 Purkinje cell-granule cell precursor cell signalling involved in regulation of granule cell precursor cell proliferation The process that mediates the transfer of information from Purkinje cells to granule cell precursors resulting in an increase in rate of granule cell precursor cell proliferation. CHEBI:46774 polyether biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46774 CHEBI:46775 N-alkylpyrrolidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46775 CHEBI:46770 pyrrolidinecarboxamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46770 GO:0021927 deep nuclear neuron precursor proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021927 The multiplication or reproduction of neuroblasts that will give rise to deep nuclear neurons. GO:0021928 basket cell precursor proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021928 The multiplication or reproduction of neuroblasts that will give rise to basket cells. A cerebellar basket cell is an inhibitory GABAergic interneuron found in the cerebellar cortex. GO:0021929 stellate cell precursor proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021929 The multiplication or reproduction of neuroblasts that will give rise to stellate cells. A cerebellar stellate cell is an inhibitory GABAergic interneuron found in the cerebellar cortex. GO:0021920 obsolete regulation of transcription from RNA polymerase II promoter involved in spinal cord association neuron specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021920 OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of neuronal precursors to association neurons in the dorsal spinal cord. GO:0021921 regulation of cell proliferation in dorsal spinal cord biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021921 The process that modulates the frequency, rate or extent of cell proliferation in the dorsal spinal cord. GO:0021922 Wnt signaling pathway involved in regulation of cell proliferation in dorsal spinal cord biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021922 Wnt receptor signaling pathway involved in regulation of cell proliferation in dorsal spinal cord|Wnt receptor signalling pathway involved in regulation of cell proliferation in dorsal spinal cord|Wnt-activated signaling pathway involved in regulation of cell proliferation in dorsal spinal cord The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of a cell in the dorsal spinal cord that affects the rate of its division. GO:0021923 cell proliferation in hindbrain ventricular zone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021923 The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain region that is adjacent to the ventricular cavity. GO:0021924 cell proliferation in external granule layer biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021924 The multiplication or reproduction of neuroblasts resulting in the expansion of a cell population in the external granule layer of the hindbrain. The external granule layer is the layer that originates from the rostral half of the rhombic lip in the first rhombomere. GO:0021925 cerebellar Purkinje cell precursor proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021925 The multiplication or reproduction of neuroblasts that will give rise to Purkinje cells. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem. GO:0021926 Golgi cell precursor proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021926 The multiplication or reproduction of neuroblasts that will give rise to Golgi cells. A Golgi cell is an inhibitory GABAergic interneuron found in the cerebellar cortex. CHEBI:46761 dipeptide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46761 CHEBI:46762 (E,E,E)-geranylgeraniol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46762 CHEBI:46765 carbapenem biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46765 CHEBI:46767 pyrrolidinecarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46767 CHEBI:4743 ecgonine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_4743 GO:0021916 inductive cell-cell signaling between paraxial mesoderm and motor neuron precursors biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021916 inductive cell-cell signalling between paraxial mesoderm and motor neuron precursors Short range signaling between cells of the paraxial mesoderm and motor neuron precursors in the spinal cord that specifies the fate of the motor column neuron precursors along the anterior-posterior axis. GO:0021917 somatic motor neuron fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021917 The commitment of unspecified motor neurons to specific motor neuron cell along the anterior-posterior axis of the spinal cord and their capacity to differentiate into specific motor neurons. GO:0021918 obsolete regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021918 OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of spinal cord motor neurons to specific motor neuron types along the anterior-posterior axis. GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021919 bone morphogenetic protein signaling pathway in spinal cord dorsal-ventral patterning|BMP signaling pathway in spinal cord dorsoventral patterning|BMP signaling pathway involved in spinal cord dorsal-ventral patterning|BMP signalling pathway involved in spinal cord dorsal-ventral patterning|bone morphogenetic protein signalling pathway involved in spinal cord dorsal-ventral patterning A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the spatial identity of regions along the dorsal-ventral axis of the spinal cord. CHEBI:4746 echinenone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_4746 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021910 hedgehog signaling pathway involved in ventral spinal cord patterning|hh signaling pathway involved in ventral spinal cord patterning|smoothened signalling pathway in ventral spinal cord patterning The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened that results in the spatial identity of regions along the dorsal-ventral axis of the spinal cord. GO:0021911 retinoic acid metabolic process in spinal cord anterior-posterior patterning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021911 retinoic acid metabolism in spinal cord anterior-posterior patterning The chemical reactions and pathways involving the synthesis and degradation of retionic acid that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord. GO:0021912 obsolete regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021912 OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that results the commitment of a cell to become a motor neuron in the ventral spinal cord. GO:0021913 obsolete regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021913 OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that results in the commitment of a cell to become an interneuron in the ventral spinal cord. GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021914 negative regulation of hedgehog signaling pathway involved in ventral spinal cord patterning|negative regulation of hh signaling pathway involved in ventral spinal cord patterning|down-regulation of smoothened signaling pathway in ventral spinal cord patterning|negative regulation of smoothened signalling pathway in ventral spinal cord patterning|downregulation of smoothened signaling pathway in ventral spinal cord patterning|down regulation of smoothened signaling pathway in ventral spinal cord patterning|inhibition of smoothened signaling pathway in ventral spinal cord patterning Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling that is involved in the patterns of cell differentiation in the ventral spinal cord. GO:0021915 neural tube development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021915 The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium. CHEBI:22788 beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-D-glucosylceramide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_22788 GO:0021905 forebrain-midbrain boundary formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021905 The process whose specific outcome is the creation of the forebrain-midbrain boundary. GO:0021906 hindbrain-spinal cord boundary formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021906 The process whose specific outcome is the formation of the hindbrain-spinal cord boundary. GO:0021907 fibroblast growth factor receptor signaling pathway involved in spinal cord anterior/posterior pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021907 fibroblast growth factor receptor signalling pathway in spinal cord anterior-posterior patterning The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord. GO:0021908 retinoic acid receptor signaling pathway involved in spinal cord anterior/posterior pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021908 retinoic acid receptor signalling pathway in spinal cord anterior-posterior patterning The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord. GO:0021909 obsolete regulation of transcription from RNA polymerase II promoter involved in spinal cord anterior-posterior patterning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021909 OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord. GO:0021900 ventricular zone cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021900 The commitment of neuroblast to become a basal progenitor cell. Basal progenitor cells are neuronal precursor cells that are committed to becoming neurons. GO:0021901 early neuron fate commitment in forebrain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021901 The commitment of neuroepithelial cell to become a neuron that will reside in the forebrain. GO:0021902 commitment of neuronal cell to specific neuron type in forebrain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021902 The commitment of neuronal precursor cells to become specialized types of neurons in the forebrain. GO:0021903 rostrocaudal neural tube patterning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021903 anterior-posterior neural tube patterning The process in which the neural tube is divided into specific regions along the rostrocaudal axis. GO:0021904 dorsal/ventral neural tube patterning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021904 dorsoventral neural tube patterning|dorsal-ventral neural tube patterning The process in which the neural tube is regionalized in the dorsoventral axis. CHEBI:46740 glycyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46740 CHEBI:22798 beta-D-glucoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_22798 CHEBI:32115 salvianin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32115 CHEBI:46731 alkyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46731 CHEBI:46733 oxabicycloalkane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46733 CHEBI:46734 (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46734 GOREL:0000040 results_in biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GOREL_0000040 GOREL:0000040 CHEBI:116931 nipecotic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_116931 CHEBI:46738 glycino group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46738 CHEBI:46722 carbonate ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46722 CHEBI:46723 phosphate mineral biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46723 CHEBI:22778 beta-D-galactosyl groups biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22778 GO:0031469 polyhedral organelle biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0031469 BAC|bacterial microcompartment An organelle found in bacteria consisting of a proteinaceous coat containing metabolic enzymes whose purpose is the sequestration or concentration of metabolites and which has the appearance of a polygonal granule by electron microscopy. GO:0031467 Cul7-RING ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031467 cullin-RING ligase 7|SCF7 complex|CRL7 complex|CDL7 complex A ubiquitin ligase complex in which a cullin from the Cul7 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 linker and an F-box protein. GO:0031468 nuclear envelope reassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031468 The reformation of the nuclear envelope following its breakdown in the context of a normal process. GO:0031465 Cul4B-RING E3 ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031465 cullin-RING ligase 4B A ubiquitin ligase complex in which a cullin from the Cul4B subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by unknown subunits. GO:0031466 Cul5-RING ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031466 CDL5 complex|cullin-RING ligase 5|SCF5 complex|CRL5 complex|EC2S complex A ubiquitin ligase complex in which a cullin from the Cul5 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an elongin-BC adaptor and a SOCS/BC box protein. CHEBI:4593 dihydroxyfumaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_4593 GO:0031463 Cul3-RING ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031463 CDL3 complex|cullin-RING ligase 3|BCR3 complex|SCF3 complex|CRL3 complex|BC3B complex A ubiquitin ligase complex in which a cullin from the Cul3 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a BTB-domain-containing protein. GO:0031464 Cul4A-RING E3 ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031464 CDL4 complex|VDC complex|cullin-RING ligase 4A|SCF4 complex|DCX complex|CRL4 complex A ubiquitin ligase complex in which a cullin from the Cul4A subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein. GO:0031461 cullin-RING ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031461 CRL complex|cullin complex|cullin-RING ligase Any ubiquitin ligase complex in which the catalytic core consists of a member of the cullin family and a RING domain protein; the core is associated with one or more additional proteins that confer substrate specificity. GO:0031462 Cul2-RING ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031462 CDL2 complex|cullin-RING ligase 2|VBC complex|CBC complex|SCF2 complex|CRL2 complex|EC2S complex|ECS complex A ubiquitin ligase complex in which a cullin from the Cul2 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an elongin-BC adaptor and a SOCS/BC box protein. GO:0031460 glycine betaine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031460 N-trimethylglycine transport The directed movement of glycine betaine, N-trimethylglycine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0031458 ABC-type betaine transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031458 betaine ABC transporter|ABC-type betaine transmembrane transporter activity|ATP-dependent betaine transporter activity|ATPase-coupled betaine transporter activity|betaine-transporting ATPase activity Catalysis of the reaction: ATP + H2O + a betaine(out) = ADP + phosphate + a betaine(in). GO:0031459 ABC-type glycine betaine transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031459 RHEA:32783 ATP-dependent glycine betaine transporter activity|ATPase-coupled glycine betaine transporter activity|glycine betaine ABC transporter|glycine betaine-transporting ATPase activity|N-trimethylglycine-transporting ATPase activity Catalysis of the reaction: ATP + H2O + glycine betaine(out) = ADP + phosphate + glycine betaine(in). GO:0031456 glycine betaine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031456 glycine betaine biosynthesis|N-trimethylglycine biosynthetic process|N-trimethylglycine biosynthesis|glycine betaine anabolism|glycine betaine synthesis|glycine betaine formation The chemical reactions and pathways resulting in the formation of glycine betaine, N-trimethylglycine. GO:0031457 glycine betaine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031457 N-trimethylglycine catabolism|glycine betaine degradation|N-trimethylglycine catabolic process|glycine betaine breakdown|glycine betaine catabolism The chemical reactions and pathways resulting in the breakdown of glycine betaine, N-trimethylglycine. CHEBI:141997 hydroxy-L-argininium residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_141997 GO:0031454 regulation of extent of heterochromatin assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031454 regulation of extent of heterochromatin formation|regulation of heterochromatin spreading Any process that modulates the extent or location of heterochromatin formation. GO:0031455 glycine betaine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031455 N-trimethylglycine metabolic process|glycine betaine metabolism|N-trimethylglycine metabolism The chemical reactions and pathways involving glycine betaine, N-trimethylglycine. GO:0031452 negative regulation of heterochromatin assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031452 inhibition of heterochromatin formation|down regulation of heterochromatin formation|downregulation of heterochromatin formation|negative regulation of heterochromatin formation|down-regulation of heterochromatin formation Any process that stops, prevents, or reduces the frequency, rate or extent of heterochromatin formation. GO:0031453 positive regulation of heterochromatin assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031453 up-regulation of heterochromatin formation|upregulation of heterochromatin formation|up regulation of heterochromatin formation|activation of heterochromatin formation|positive regulation of heterochromatin formation|stimulation of heterochromatin formation Any process that activates or increases the frequency, rate or extent of heterochromatin formation. GO:0031450 negative regulation of slow-twitch skeletal muscle fiber contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031450 inhibition of slow-twitch skeletal muscle contraction|down regulation of slow-twitch skeletal muscle contraction|negative regulation of slow-twitch skeletal muscle contraction|downregulation of slow-twitch skeletal muscle contraction|down-regulation of slow-twitch skeletal muscle contraction Any process that stops, prevents, or reduces the frequency, rate or extent of slow-twitch skeletal muscle contraction. GO:0031451 positive regulation of slow-twitch skeletal muscle fiber contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031451 up-regulation of slow-twitch skeletal muscle contraction|upregulation of slow-twitch skeletal muscle contraction|positive regulation of slow-twitch skeletal muscle contraction|up regulation of slow-twitch skeletal muscle contraction|activation of slow-twitch skeletal muscle contraction|stimulation of slow-twitch skeletal muscle contraction Any process that activates or increases the frequency, rate or extent of slow-twitch skeletal muscle contraction. GO:0031449 regulation of slow-twitch skeletal muscle fiber contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031449 regulation of slow-twitch skeletal muscle contraction Any process that modulates the frequency, rate or extent of slow-twitch skeletal muscle contraction. GO:0031447 negative regulation of fast-twitch skeletal muscle fiber contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031447 downregulation of fast-twitch skeletal muscle contraction|down-regulation of fast-twitch skeletal muscle contraction|inhibition of fast-twitch skeletal muscle contraction|down regulation of fast-twitch skeletal muscle contraction|negative regulation of fast-twitch skeletal muscle contraction Any process that stops, prevents, or reduces the frequency, rate or extent of fast-twitch skeletal muscle contraction. GO:0031448 positive regulation of fast-twitch skeletal muscle fiber contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031448 up regulation of fast-twitch skeletal muscle contraction|activation of fast-twitch skeletal muscle contraction|stimulation of fast-twitch skeletal muscle contraction|up-regulation of fast-twitch skeletal muscle contraction|upregulation of fast-twitch skeletal muscle contraction|positive regulation of fast-twitch skeletal muscle contraction Any process that activates or increases the frequency, rate or extent of fast-twitch skeletal muscle contraction. GO:0006489 dolichyl diphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006489 dolichyl diphosphate biosynthesis|dolichyl diphosphate anabolism|dolichyl diphosphate synthesis|dolichyl diphosphate formation The chemical reactions and pathways resulting in the formation of dolichyl diphosphate, a diphosphorylated dolichol derivative. GO:0031445 regulation of heterochromatin assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031445 regulation of heterochromatin formation Any process that modulates the frequency, rate, extent or location of heterochromatin formation. GO:0031446 regulation of fast-twitch skeletal muscle fiber contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031446 regulation of fast-twitch skeletal muscle contraction Any process that modulates the frequency, rate or extent of fast-twitch skeletal muscle contraction. GO:0006487 protein N-linked glycosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006487 RESID:AA0327|RESID:AA0156|RESID:AA0151 N-glycan biosynthesis|N-glycan metabolism|protein amino acid N-linked glycosylation A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the N4 atom of peptidyl-asparagine, the omega-N of arginine, or the N1' atom peptidyl-tryptophan. GO:0006488 dolichol-linked oligosaccharide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006488 oligosaccharide-PP-dolichol assembly|dolichol-linked oligosaccharide anabolism|dolichol-linked oligosaccharide synthesis|dolichol-linked oligosaccharide formation|dolichol-linked oligosaccharide biosynthesis|N-linked glycan precursor biosynthesis|N-linked glycan precursor biosynthetic process The chemical reactions and pathways resulting in the formation of dolichol-linked oligosaccharide, usually by a stepwise addition of glycosyl chains to endoplasmic reticulum membrane-bound dolichol-P. GO:0006485 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006485 GO:0006486 protein glycosylation biolink:BiologicalProcess go-plus goslim_yeast|goslim_pombe http://purl.obolibrary.org/obo/GO_0006486 protein amino acid glycosylation|protein-carbohydrate complex assembly A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins. GO:0006483 obsolete peptidyl-aspartic acid/asparagine hydroxylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006483 peptidyl-aspartic acid/asparagine hydroxylation|aspartic acid/asparagine hydroxylation OBSOLETE. The hydroxylation of peptidyl-aspartic acid or asparagine. GO:0006484 obsolete protein cysteine-thiol oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006484 protein cysteine-thiol oxidation OBSOLETE. Oxidation of two cysteine sulfhydryl groups (thiols) in one protein by a disulfide bond in a second protein to form a disulfide bond in the first protein and two reduced sulfhydryls in the second. The oxidized cysteines linked by a disulfide bond is known as cystine. GO:0006481 C-terminal protein methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006481 C-terminal protein amino acid methylation The methylation of the C-terminal amino acid of a protein. GO:0006482 protein demethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006482 protein amino acid demethylation The removal of a methyl group, from a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom. GO:0006490 oligosaccharide-lipid intermediate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006490 oligosaccharide-lipid intermediate biosynthetic process|oligosaccharide-lipid intermediate assembly The chemical reactions and pathways resulting in the formation of an oligosaccharide-lipid intermediate, such as a molecule of dolichol-P-man or dolicol-P-Glc used in N-linked glycosylation. CHEBI:4579 dihydropinosylvin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_4579 GO:0006491 N-glycan processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006491 glycoprotein trimming involved in glycoprotein maturation|N-linked glycoprotein maturation The conversion of N-linked glycan (N = nitrogen) structures from the initially transferred oligosaccharide to a mature form, by the actions of glycosidases and glycosyltransferases. The early processing steps are conserved and play roles in glycoprotein folding and trafficking. GO:0031443 fast-twitch skeletal muscle fiber contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031443 fast-twitch skeletal fibre contraction|fast-twitch skeletal fiber contraction|fast-twitch skeletal myofibre contraction|fast-twitch skeletal myofiber contraction|fast-twitch skeletal muscle fibre contraction A process in which force is generated within fast-twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The fast-twitch skeletal muscle is characterized by fast time parameters, high force development and fatiguability. GO:0031444 slow-twitch skeletal muscle fiber contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031444 slow-twitch skeletal muscle fibre contraction A process in which force is generated within slow-twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The slow-twitch skeletal muscle is characterized by slow time parameters, low force development and resistance to fatigue. GO:0031441 negative regulation of mRNA 3'-end processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031441 down regulation of mRNA 3'-end processing|inhibition of mRNA 3'-end processing|down-regulation of mRNA 3'-end processing|downregulation of mRNA 3'-end processing Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA 3'-end processing. GO:0031442 positive regulation of mRNA 3'-end processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031442 upregulation of mRNA 3'-end processing|stimulation of mRNA 3'-end processing|up-regulation of mRNA 3'-end processing|activation of mRNA 3'-end processing|up regulation of mRNA 3'-end processing Any process that activates or increases the frequency, rate or extent of mRNA 3'-end processing. GO:0031440 regulation of mRNA 3'-end processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031440 Any process that modulates the frequency, rate or extent of mRNA 3'-end processing, any process involved in forming the mature 3' end of an mRNA molecule. GO:0031438 negative regulation of mRNA cleavage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031438 down regulation of mRNA cleavage|downregulation of mRNA cleavage|down-regulation of mRNA cleavage|inhibition of mRNA cleavage Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA cleavage. GO:0031439 positive regulation of mRNA cleavage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031439 up-regulation of mRNA cleavage|upregulation of mRNA cleavage|up regulation of mRNA cleavage|activation of mRNA cleavage|stimulation of mRNA cleavage Any process that activates or increases the frequency, rate or extent of mRNA cleavage. GO:0031436 BRCA1-BARD1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031436 A heterodimeric complex comprising BRCA1 and BARD1, which possesses ubiquitin ligase activity and is involved in genome maintenance, possibly by functioning in surveillance for DNA damage. GO:0031437 regulation of mRNA cleavage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031437 Any process that modulates the frequency, rate or extent of mRNA cleavage, any process in which a pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner. GO:0031434 mitogen-activated protein kinase kinase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031434 MAPKK binding Interacting selectively and non-covalently with a mitogen-activated protein kinase kinase, any protein that can phosphorylate a MAP kinase. GO:0031435 mitogen-activated protein kinase kinase kinase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031435 MAPKKK binding Interacting selectively and non-covalently with a mitogen-activated protein kinase kinase kinase, any protein that can phosphorylate a MAP kinase kinase. GO:0006498 N-terminal protein lipidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006498 The covalent attachment of a lipid group to the amino terminus of a protein. CHEBI:356445 glycylglycine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_356445 GO:0006499 N-terminal protein myristoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006499 The covalent attachment of a myristoyl group to the N-terminal amino acid residue of a protein. GO:0006496 obsolete protein amino acid terminal N-glycosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006496 protein amino acid terminal N-glycosylation OBSOLETE. The glycosylation of a nitrogen atom of a free alpha amino terminal of a peptide. GO:0006497 protein lipidation biolink:BiologicalProcess go-plus goslim_yeast|goslim_drosophila http://purl.obolibrary.org/obo/GO_0006497 RESID:AA0077|RESID:AA0163|RESID:AA0162|RESID:AA0161|RESID:AA0160|RESID:AA0060|RESID:AA0290|RESID:AA0080|RESID:AA0309|RESID:AA0308|RESID:AA0307|RESID:AA0107|RESID:AA0316|RESID:AA0106|RESID:AA0104|RESID:AA0159|RESID:AA0059|RESID:AA0103|RESID:AA0158|RESID:AA0223|RESID:AA0102|RESID:AA0079|RESID:AA0078|RESID:AA0166 protein amino acid lipidation|lipid:protein modification The covalent attachment of lipid groups to an amino acid in a protein. GO:0006494 obsolete protein amino acid terminal glycosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006494 protein amino acid terminal glycosylation OBSOLETE. A protein amino acid glycosylation process in which a sugar unit is added to a free alpha-amino or alpha-carboxyl terminal of a peptide. GO:0006495 obsolete terminal O-glycosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006495 terminal O-glycosylation OBSOLETE. (Was not defined before being made obsolete). GO:0006492 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006492 GO:0006493 protein O-linked glycosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006493 RESID:AA0212|RESID:AA0157|RESID:AA0155|RESID:AA0154|RESID:AA0153 protein amino acid O-linked glycosylation A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the hydroxyl group of peptidyl-serine, peptidyl-threonine, peptidyl-hydroxylysine, or peptidyl-hydroxyproline, or via the phenol group of peptidyl-tyrosine, forming an O-glycan. CHEBI:4581 7,8-dihydropteroic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_4581 GO:0031432 titin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031432 Interacting selectively and non-covalently with titin, any of a family of giant proteins found in striated and smooth muscle. In striated muscle, single titin molecules span half the sarcomere, with their N- and C-termini in the Z-disc and M-line, respectively. GO:0031433 telethonin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031433 Interacting selectively and non-covalently with telethonin, a protein found in the Z disc of striated muscle and which is a substrate of the titin kinase. GO:0031430 M band biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031430 Wikipedia:Sarcomere#bands M line|M disc|mesophragma|midline The midline of aligned thick filaments in a sarcomere; location of specific proteins that link thick filaments. Depending on muscle type the M band consists of different numbers of M lines. GO:0031431 Dbf4-dependent protein kinase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031431 DDK|Cdc7-Dbf4 complex|Hsk1-Dfp1 kinase complex A heterodimeric protein complex required for the activation of DNA replication origins; comprises a catalytic subunit and a regulatory subunit (in Saccharomyces, Cdc7p and Dbf4p, respectively); complexes identified in other species generally contain proteins related to the Saccharomyces proteins. CHEBI:32096 rhodomycin D biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32096 GO:0031429 box H/ACA snoRNP complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031429 box H/ACA small nucleolar ribonucleoprotein complex|box H/ACA snoRNP pseudouridylase complex A box H/ACA RNP complex that is located in the nucleolus. GO:0031427 response to methotrexate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031427 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methotrexate stimulus. Methotrexate is 4-amino-10-methylformic acid, a folic acid analogue that is a potent competitive inhibitor of dihydrofolate reductase. GO:0031428 box C/D RNP complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031428 box C/D snoRNP ribose-2'-O-methyltransferase complex|box C/D small nucleolar ribonucleoprotein complex|box C/D snoRNP complex|box C/D snoRNP ribose 2'-O methylase complex|box C/D sRNP complex A ribonucleoprotein complex containing a box C/D type RNA that can carry out ribose-2'-O-methylation of target RNAs. Box C/D type RNAs are widespread in eukaryotes and in Archaea, suggesting that an RNA-based guide mechanism for directing specific RNA 2'-O-ribose methylations was present in the common ancestor of Archaea and Eukarya. GO:0031425 chloroplast RNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031425 The conversion of a primary RNA molecule transcribed from a chloroplast genome into one or more mature RNA molecules. GO:0006469 negative regulation of protein kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006469 down-regulation of protein kinase activity|inhibition of protein kinase activity|down regulation of protein kinase activity|downregulation of protein kinase activity Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity. GO:0031426 polycistronic mRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031426 The conversion of a primary mRNA transcript containing more than one complete protein-coding region into individual mature mRNA molecules. GO:0031423 hexon binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031423 Interacting selectively and non-covalently with a hexon, the major protein component of the icosahedral capsid of an adenovirus. GO:0006467 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006467 GO:0006468 protein phosphorylation biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0006468 protein amino acid phosphorylation The process of introducing a phosphate group on to a protein. GO:0031424 keratinization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031424 The process in which the cytoplasm of the outermost cells of the vertebrate epidermis is replaced by keratin. Keratinization occurs in the stratum corneum, feathers, hair, claws, nails, hooves, and horns. GO:0006465 signal peptide processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006465 leader peptide processing The proteolytic removal of a signal peptide from a protein during or after transport to a specific location in the cell. GO:0006466 obsolete protein disulfide-isomerase reaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006466 protein disulphide-isomerase reaction|protein disulfide-isomerase reaction OBSOLETE. (Was not defined before being made obsolete). GO:0006463 steroid hormone receptor complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006463 The aggregation, arrangement and bonding together of a set of components to form a steroid hormone receptor complex, an intracellular receptor that binds steroid hormones. The complex is often a dimer, and forms after the steroid has bound the receptor. GO:0006464 cellular protein modification process biolink:BiologicalProcess go-plus goslim_chembl|goslim_candida|goslim_plant|goslim_pir|goslim_aspergillus|goslim_generic http://purl.obolibrary.org/obo/GO_0006464 protein tagging activity|process resulting in protein modification|protein modification process The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification). GO:0006461 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006461 GO:0006462 obsolete protein complex assembly, multichaperone pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006462 protein complex assembly, multichaperone pathway OBSOLETE. (Was not defined before being made obsolete). GO:0006460 obsolete peptidyl-prolyl isomerase B reaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006460 peptidyl-prolyl isomerase B reaction OBSOLETE. (Was not defined before being made obsolete). GO:0031421 invertasome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031421 A complex formed by a recombinase, a regulatory protein, and the DNA sequences bound by each protein; catalyzes a reversible site-specific recombination reaction that results in the alternate expression of one or more genes in various contexts. GO:0031422 RecQ family helicase-topoisomerase III complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031422 Sgs1-Top3 complex|RecQ helicase-Topo III complex A complex containing a RecQ family helicase and a topoisomerase III homologue (a member of the topoisomerase type IA subfamily); may also include one or more additional proteins; conserved from E. coli to human. GO:0031420 alkali metal ion binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031420 Interacting selectively and non-covalently with any alkali metal ion; alkali metals are those elements in group Ia of the periodic table, with the exception of hydrogen. GO:0031418 L-ascorbic acid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031418 L-ascorbate binding|vitamin C binding Interacting selectively and non-covalently with L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species. GO:0031419 cobalamin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031419 vitamin B12 binding Interacting selectively and non-covalently with cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom. GO:0031416 NatB complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031416 N-terminal acetyltransferase B complex A conserved complex that catalyzes the transfer of an acetyl group to the N-terminal residue of a protein acceptor molecule that has a Met-Glu, Met-Asp, Met-Asn, or Met-Met N-terminus. In Saccharomyces the complex includes Nat3p and Mdm20p. GO:0031417 NatC complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031417 N-terminal acetyltransferase C complex A conserved complex that catalyzes the transfer of an acetyl group to the N-terminal residue of a protein acceptor molecule that has a Met-Ile, Met-Leu, Met-Trp, or Met-Phe N-terminus. In Saccharomyces the complex includes Mak3p, Mak10p, and Mak31p. GO:0031414 N-terminal protein acetyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031414 NAT complex A complex that catalyzes the transfer of an acetyl group to the N-terminal residue of a protein acceptor molecule. GO:0031415 NatA complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031415 N-terminal acetyltransferase A complex A conserved complex that catalyzes the transfer of an acetyl group to an N-terminal Ser, Ala, Gly, or Thr residue of a protein acceptor molecule. In Saccharomyces the complex includes Nat1p and Ard1p, and may contain additional proteins. GO:0006478 peptidyl-tyrosine sulfation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006478 RESID:AA0172 peptidyl-tyrosine sulphation The sulfation of peptidyl-tyrosine residues to form peptidyl-O4'-sulfo-L-tyrosine. GO:0031412 gas vesicle organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031412 gas vesicle organisation|gas vesicle formation|gas vesicle organization and biogenesis|gas vesicle biosynthesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a gas vesicle. A gas vesicle is a hollow structure made of protein, which usually has the form of a cylindrical tube closed by conical end caps. GO:0031413 regulation of buoyancy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031413 buoyancy regulation Any process that modulates an organism's tendency or ability to rise or float in a fluid medium such as water or air, often through the use of stored gases. GO:0006479 protein methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006479 protein amino acid methylation The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom. GO:0006476 protein deacetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006476 protein amino acid deacetylation The removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid. GO:0006477 protein sulfation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006477 protein amino acid sulfation|protein amino acid sulphation The addition of a sulfate group as an ester to a protein amino acid. GO:0006474 N-terminal protein amino acid acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006474 N(alpha)-terminal acetylation The acetylation of the N-terminal amino acid of proteins. GO:0006475 internal protein amino acid acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006475 The addition of an acetyl group to a non-terminal amino acid in a protein. GO:0006472 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006472 GO:0006473 protein acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006473 protein amino acid acetylation The addition of an acetyl group to a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid. GO:0006470 protein dephosphorylation biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0006470 protein amino acid dephosphorylation The process of removing one or more phosphoric residues from a protein. GO:0006471 protein ADP-ribosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006471 RESID:AA0231|RESID:AA0295|RESID:AA0040|RESID:AA0237|RESID:AA0169|RESID:AA0168 protein amino acid ADP-ribosylation The transfer, from NAD, of ADP-ribose to protein amino acids. GO:0006480 N-terminal protein amino acid methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006480 The methylation of the N-terminal amino acid of a protein. CHEBI:32079 pyrrolnitrin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32079 GO:0031410 cytoplasmic vesicle biolink:CellularComponent go-plus goslim_candida|goslim_agr|goslim_yeast|goslim_aspergillus|goslim_generic|goslim_chembl|goslim_mouse http://purl.obolibrary.org/obo/GO_0031410 NIF_Subcellular:sao180601769 cytoplasmic, membrane-bounded vesicle|cytoplasmic membrane-enclosed vesicle|cytoplasmic membrane bounded vesicle A vesicle found in the cytoplasm of a cell. GO:0031411 gas vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031411 gas vacuole An intracellular non-membrane-bounded organelle; a hollow structure made of protein, which usually has the form of a cylindrical tube closed by conical end caps. By regulating their relative gas vesicle content, aquatic microbes are able to perform vertical migrations. CHEBI:46695 fluorohydrocarbon biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46695 GO:0031407 oxylipin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031407 oxylipin metabolism The chemical reactions and pathways involving any oxylipin, any of a group of biologically active compounds formed by oxidative metabolism of polyunsaturated fatty acids. GO:0031408 oxylipin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031408 oxylipin biosynthesis|oxylipin anabolism|oxylipin synthesis|oxylipin formation The chemical reactions and pathways resulting in the formation of any oxylipin, any of a group of biologically active compounds formed by oxidative metabolism of polyunsaturated fatty acids. GO:0006449 regulation of translational termination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006449 Any process that modulates the frequency, rate or extent of translational termination. GO:0031405 lipoic acid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031405 Interacting selectively and non-covalently with lipoic acid, 1,2-dithiolane-3-pentanoic acid. GO:0031406 carboxylic acid binding biolink:MolecularActivity go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0031406 Interacting selectively and non-covalently with a carboxylic acid, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-). GO:0031403 lithium ion binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031403 Interacting selectively and non-covalently with lithium ions (Li+). GO:0006447 regulation of translational initiation by iron biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006447 Any process that modulates the frequency, rate or extent of the translation of certain mRNAs involved in iron metabolism; regulated by the concentration of iron. GO:0031404 chloride ion binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031404 chloride binding Interacting selectively and non-covalently with chloride ions (Cl-). GO:0006448 regulation of translational elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006448 Any process that modulates the frequency, rate, extent or accuracy of translational elongation. GO:0006445 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006445 GO:0031401 positive regulation of protein modification process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031401 stimulation of protein modification|up-regulation of protein modification|activation of protein modification|up regulation of protein modification|upregulation of protein modification Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein. GO:0031402 sodium ion binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031402 Interacting selectively and non-covalently with sodium ions (Na+). GO:0006446 regulation of translational initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006446 Any process that modulates the frequency, rate or extent of translational initiation. GO:0006443 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006443 GO:0006444 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006444 GO:0006441 obsolete binding to mRNA cap biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006441 binding to mRNA cap OBSOLETE. (Was not defined before being made obsolete). GO:0006442 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006442 CHEBI:46691 2,3-dihydroxy-5-methyl-1,4-benzoquinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46691 GO:0006440 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006440 GO:0031409 pigment binding biolink:MolecularActivity go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0031409 Interacting selectively and non-covalently with a pigment, any general or particular coloring matter in living organisms, e.g. melanin. OBO:GOCHE_23357 substance with cofactor role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_23357 GO:0031400 negative regulation of protein modification process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031400 down-regulation of protein modification|downregulation of protein modification|down regulation of protein modification|inhibition of protein modification Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein. CHEBI:46685 oxadiazole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46685 CHEBI:46686 azaalkane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46686 CHEBI:46687 diazaalkane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46687 GO:0006458 'de novo' protein folding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006458 nascent chain protein folding The process of assisting in the folding of a nascent peptide chain into its correct tertiary structure. GO:0006459 obsolete binding unfolded ER proteins biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006459 binding unfolded ER proteins OBSOLETE. (Was not defined before being made obsolete). GO:0006456 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006456 GO:0006457 protein folding biolink:BiologicalProcess go-plus goslim_pir|goslim_drosophila|goslim_metagenomics|goslim_aspergillus|goslim_generic|goslim_pombe|goslim_chembl|goslim_yeast|goslim_candida http://purl.obolibrary.org/obo/GO_0006457 Wikipedia:Protein_folding co-chaperone activity|chaperone activity|co-chaperonin activity|beta-tubulin folding|chaperonin ATPase activity|protein complex assembly, multichaperone pathway|chaperonin-mediated tubulin folding|alpha-tubulin folding|non-chaperonin molecular chaperone ATPase activity|glycoprotein-specific chaperone activity The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure. GO:0006454 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006454 GO:0006455 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006455 GO:0006452 translational frameshifting biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006452 Wikipedia:Translational_frameshift A mechanism whereby different proteins may result from a single mRNA molecule, due to a change in the parsing of three nucleotides per codon relative to an initiating AUG codon. GO:0006453 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006453 GO:0006450 regulation of translational fidelity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006450 regulation of translational accuracy Any process that modulates the ability of the translational apparatus to interpret the genetic code. GO:0006451 translational readthrough biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006451 natural nonsense suppression The continuation of translation beyond a stop codon by the use of a special tRNA that recognizes the UAG and UGA codons as modified amino acids, rather than as termination codons. CHEBI:71632 pyrazine N-oxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71632 CHEBI:71633 hydroxypyrazine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71633 CHEBI:71634 hydroxyversicolorone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71634 CHEBI:71635 versicolorone(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71635 CHEBI:71636 versiconol acetate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71636 CHEBI:71637 versiconal hemiacetal acetate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71637 CHEBI:71638 versiconal hemiacetal biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71638 CHEBI:71639 versiconol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71639 CHEBI:71648 hydroxybenzoquinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71648 CHEBI:71649 (S)-5'-oxoaverantin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71649 CHEBI:71652 anthrafuran biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71652 CHEBI:71653 versicolorone tricyclic form biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71653 CHEBI:71654 versicolorone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71654 CHEBI:71657 versiconol acetate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71657 CHEBI:71662 versiconal biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71662 CHEBI:71665 (S)-versiconol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71665 CHEBI:71666 gamma-amino acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71666 CHEBI:71661 anthocyanidin 3-glucoside 5-[(6-O-4-hydroxycinnamoyl)glucoside] biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71661 CHEBI:71673 N-acetyl-D-galactosamine 6-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71673 CHEBI:71674 D-galactosamine 6-phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71674 CHEBI:71677 (2S)-2-hydroxy-3,4-diketopentyl phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71677 CHEBI:71678 N(6)-(dimethylallyl)adenosine 5'-diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71678 CHEBI:71679 N(6)-(dimethylallyl)adenosine 5'-triphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71679 CHEBI:71670 N-acetyl-L-methionine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71670 CHEBI:71671 aldonate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71671 CHEBI:71684 (2S)-2-hydroxy-3,4-diketopentyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71684 CHEBI:71685 L-4-hydroxy-2-oxoglutarate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71685 CHEBI:71688 7-epi-zingiberene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71688 CHEBI:71689 L-4-hydroxy-2-oxoglutaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71689 GO:0031490 chromatin DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031490 Interacting selectively and non-covalently with DNA that is assembled into chromatin. GO:0031491 nucleosome binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031491 Interacting selectively and non-covalently with a nucleosome, a complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures. GO:0031498 chromatin disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031498 The controlled breakdown of chromatin from a higher order structure into its simpler subcomponents, DNA, histones, other proteins, and sometimes RNA. GO:0031499 TRAMP complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031499 Wikipedia:TRAMP_complex TRAMP5 complex|TRAMP4 complex|Trf4 complex|Trf4p-Air2p-Mtr4p polyadenylation complex|Trf4 poly(A) polymerase complex A multiprotein complex having distributive polyadenylation activity of a variety of RNA substrates including hypomodified and incorrectly folded tRNAs, pre-snRNAs, pre-snoRNAs, incorrectly spliced or processed pre-mRNAs, cryptic unstable transcripts (CUTs), pre-rRNAs and rRNA fragments released as part of rRNA processing. In S. cerevisiae, the complex consists of either Pap2 (also known as Trf4) or Trf5, Air1 or Air2, and Mtr4, and is involved in RNA 3'-end processing and in RNA surveillance and quality control. GO:0031496 positive regulation of mating type switching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031496 up-regulation of mating type switching|upregulation of mating type switching|up regulation of mating type switching|activation of mating type switching|stimulation of mating type switching Any process that activates or increases the frequency, rate or extent of mating type switching. GO:0031497 chromatin assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031497 establishment of chromatin architecture The assembly of DNA, histone proteins, other associated proteins, and sometimes RNA, into chromatin structure, beginning with the formation of the basic unit, the nucleosome, followed by organization of the nucleosomes into higher order structures, ultimately giving rise to a complex organization of specific domains within the nucleus. GO:0031494 regulation of mating type switching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031494 Any process that modulates the frequency, rate or extent of mating type switching, the conversion of a single-cell organism from one mating type to another by the precise replacement of a DNA sequence at the expressed mating type locus with a copy of a sequence from a donor locus. GO:0031495 negative regulation of mating type switching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031495 inhibition of mating type switching|down regulation of mating type switching|downregulation of mating type switching|down-regulation of mating type switching Any process that stops, prevents, or reduces the frequency, rate or extent of mating type switching. CHEBI:71681 D-gamma-glutamyl-D-glutamate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71681 GO:0031492 nucleosomal DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031492 Interacting selectively and non-covalently with the DNA portion of a nucleosome. CHEBI:71682 cyanidin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71682 GO:0031493 nucleosomal histone binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031493 Interacting selectively and non-covalently with a histone that is assembled into a nucleosome. CHEBI:71683 D-gamma-glutamyl-D-glutamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71683 GO:0031489 myosin V binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031489 Interacting selectively and non-covalently with a class V myosin; myosin V is a dimeric molecule involved in intracellular transport. CHEBI:81014 3beta-hydroxycholest-5-en-26-oic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_81014 CHEBI:81013 7alpha,25-dihydroxy-4-cholesten-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_81013 GO:0031480 myosin X complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031480 A myosin complex containing one or more class X myosin heavy chains and associated light chains. GO:0031487 myosin XVII complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031487 A myosin complex containing one or more class XVII myosin heavy chains and associated light chains. GO:0031488 myosin XVIII complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031488 A myosin complex containing a class XVIII myosin heavy chain and associated light chains; myosin XVIII heavy chains contain an N-terminal PDZ domain. GO:0031485 myosin XV complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031485 A myosin complex containing a class XV myosin heavy chain and associated light chains. Myosin XV is single headed, and has a large extension (1200aa) at the N-terminus of the motor domain, two IQ motifs and a tail with a similar domain structure to that of the tail of myosin VII. GO:0031486 myosin XVI complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031486 A myosin complex containing a class XVI myosin heavy chains and associated light chains; myosin XVI heavy chains contain ankyrin repeat. GO:0031483 myosin XIII complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031483 A myosin complex containing one or more class XIII myosin heavy chains and associated light chains. GO:0031484 myosin XIV complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031484 A myosin complex containing a class XIV myosin heavy chain and associated light chains; myosin XIV heavy chains are the simplest known, containing a motor domain, no classic IQ motif and variable length tails. CHEBI:71692 insect repellent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71692 GO:0031481 myosin XI complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031481 A myosin complex containing a dimer of class XI myosin heavy chains and associated light chains. Myosin XI heavy chain sizes are similar in molecular structure to the class V myosins with 5 to 6 IQ motifs and tail regions with predicted coiled coil domains (forming dimeric molecules) and large C-terminal regions. GO:0031482 myosin XII complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031482 A myosin complex containing one or more class XII myosin heavy chains and associated light chains; myosin XII contains a large tail region with two MyTH4 domains and a short region of coiled coil. GO:0031478 myosin VIII complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031478 A myosin complex containing a dimer of class VIII myosin heavy chains and associated light chains. Myosin VIII is predicted to be dimeric, and contain an unusual 100-190 residue N-terminal extension prior to their motor domains, 3-4 IQ motifs, a short region (~70 residues) of predicted alpha-helical coiled coil and a C-terminal domain. GO:0031479 myosin IX complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031479 A myosin complex containing a class IX myosin heavy chain and associated light chains. Myosin IX is monomeric with a motor domain containing an N-terminal extension and an insert in the actin binding interface, followed by four to six IQ motifs and a tail region that contains a zinc binding motif and a domain with homology to GTPase activating proteins (GAPs) of the Rho family of G-proteins. CHEBI:81024 nocardicin G biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_81024 CHEBI:81021 nocardicin C biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_81021 CHEBI:81022 isonocardicin C biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_81022 GO:0031476 myosin VI complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031476 A myosin complex containing one or more class VI myosin heavy chains and associated light chains. Myosin VI has a single IQ motif in the neck and a tail region with a coiled coil domain followed by a unique globular domain; a unique insertion that enables myosin VI to move towards the pointed or minus end of actin filaments. GO:0031477 myosin VII complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031477 A myosin complex containing a dimer of class VII myosin heavy chains and associated light chains. Myosin VII (240 kDa) is predicted to be a dimeric molecule with 5 IQ motifs and a tail region with a short stretch of coiled coil followed by two myosin-tail homology (MyTH4) domains, two talin-binding (FERM) domains and an SH3-domain. GO:0031474 myosin IV complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031474 A myosin complex containing one or more class IV myosin heavy chains and associated light chains; myosin IV is relatively uncharacterized, but is predicted to have a single motor domain, one IQ motif and a tail with a Myosin Tail Homology (myTH4) domain homologous to that in the tails of myosins VII and XV. GO:0031475 myosin V complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031475 A myosin complex containing a dimer of class V myosin heavy chains and associated light chains; involved in intracellular transport. Myosin V is a dimeric molecule consisting of conserved motor domains followed by 6 IQ motifs which bind specific light chains and calmodulin. The tail domain is important for cellular localization and cargo binding and can be divided into an alpha-helical coiled coil region and a C-terminal globular region. GO:0031472 propanediol degradation polyhedral organelle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031472 An organelle found in bacteria consisting of a proteinaceous coat containing enzymes for the degradation of 1,2-propanediol whose purpose is the protection of the rest of the cell from the toxic propionaldehyde product of the enzyme diol dehydratase. GO:0031473 myosin III binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031473 Interacting selectively and non-covalently with a class III myosin; myosin III is monomeric and has an N terminal kinase domain. GO:0031470 carboxysome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031470 Wikipedia:Carboxysome An organelle consisting of a proteinaceous coat and enzymes for the fixation of CO(2). It augments the concentration of CO(2) in the vicinity of RuBisCO to increase the efficiency of CO(2) fixation under atmospheric conditions. GO:0031471 ethanolamine degradation polyhedral organelle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031471 ethanolamine metabolosome An organelle found in bacteria consisting of a proteinaceous coat containing enzymes for the degradation of ethanolamine whose purpose is the protection of the rest of the cell from the toxic acetaldehyde product of the enzyme ethanolamine ammonia lyase. UBERON:0003054 roof plate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003054 roof plate neural tube|alar plate|future brain roof plate|roof plate neural tube region|roofplate A single row of glia at the dorsal midline of the developing neural tube along the entire anterior-posterior axis. This region provides inductive signals for the specification of neuronal cell types and of the specification of neural crest cells. The cells comprising the roof plate are the precursors to radial glial cells. UBERON:0003055 periderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003055 EVL|epidermis outer layer|skin periderm|epitrichium|epidermis epithelial layer|periderm A temporary epithelium that derives from the outer layer of the ectdoerm and is shed once the inner layer differentiates to form a true epidermis. UBERON:0003052 midbrain-hindbrain boundary biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003052 mid-hindbrain boundary|isthmic organizer territory|isthmus|MHB|isthmus/MHB|midbrain hindbrain boundary|mid-hindbrain junction|isthmo-cerebellar region The part of the brain that is the morphological boundary between the midbrain and hindbrain and that is the location of an organizing center which patterns the midbrain and hindbrain primordia of the neural plate. UBERON:0003053 ventricular zone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003053 brain ventricular zone|VZ|ventricular zones|ventricular zone of brain Proliferative region that is part of the ventricular system. UBERON:0003050 olfactory placode biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003050 placoda olfactoria|olfactory placodes|placoda nasalis|nasal I placode|nasal placode A thick plate of cells derived from the neural ectoderm in the head region of the embryo that develops into the olfactory region of the nasal cavity. UBERON:0003051 ear vesicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003051 otic vesicle|acoustic vesicle|auditory vesicle|OV|otocyst An epithelial sac of invaginated ectoderm formed from the otic placode that gives rise to the structures of the inner ear[MP] UBERON:0003058 hypochord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003058 ipochord|subnotochordal rod The hypochord is a transient rod-like structure in the embryos of fish, lampreys and amphibians that is located immediately ventral to the notochord. The hypochord may play a role in positioning the dorsal aorta[GO]. UBERON:0003059 presomitic mesoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003059 somitogenic mesoderm|segmental plate|presumptive somite mesoderm|unsegmented paraxial mesoderm|unsegmented mesenchyme|somitomeric mesoderm|PSM Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. UBERON:0003056 pre-chordal neural plate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003056 anterior neural plate The portion of neural plate anterior to the mid-hindbrain junction. UBERON:0003057 chordal neural plate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003057 posterior neural plate The portion of neural plate posterior to the mid-hindbrain junction. CHEBI:22629 arsenate ion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22629 CHEBI:22633 arsenite ion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22633 CHEBI:22632 arsenic molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22632 UBERON:0003043 posterior part of anterior commissure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003043 pars posterior|anterior commissure, temporal limb|anterior commissure temporal limb|anterior commissure pars posterior|anterior commissure, posterior part|temporal limb of anterior commissure|commissura anterior, pars posterior|commissura rostralis, pars posterior|pars posterior commissurae anterioris|commissura anterior, crus posterius The major forebrain commissure that connects the two temporal lobes of the cortex. UBERON:0003041 trigeminal nerve fibers biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003041 central part of trigeminal nerve|fibrae nervi trigemini|trigeminal nerve tract|trigeminal nerve fibers A nerve fiber that is part of a trigeminal nerve. CHEBI:22638 organoarsonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22638 UBERON:0003049 collagen and cuticulin-based cuticle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003049 nematode cuticle A type of cuticle composed of highly cross-linked collagens and specialised insoluble proteins known as cuticlins, together with glycoproteins and lipids[WP]. UBERON:0017672 abdominal viscera biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0017672 abdominal viscera set|abdominal viscera|set of abdominal viscera A viscus that is part of a abdomen. CHEBI:22600 arabinose phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22600 CHEBI:22601 arabinoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22601 CHEBI:22605 arabinitol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22605 UBERON:0003038 thoracic spinal cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003038 thoracic segments of spinal cord [1-12]|pars thoracica medullae spinalis|thoracic region of spinal cord|thoracic spinal cord|thoracic segment of spinal cord|segmenta thoracica medullae spinalis [1-12] The thoracic nerves are the spinal nerves emerging from the thoracic vertebrae. [WP,unvetted]. UBERON:0003039 anterior commissure anterior part biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003039 pars anterior|anterior commissure pars anterior|anterior commissure, anterior part|pars olfactoria commissurae anterioris|anterior part of anterior commissure|commissura anterior, pars olfactoria|anterior commissure olfactory limb|anterior commissure, olfactory limb|olfactory limb of anterior commissure|olfactory part of anterior commissure|commissura rostralis, pars anterior|commissura anterior, crus anterius|commissura anterior, pars anterior|pars anterior commissurae anterioris The horseshoe-shaped tract that connects the two olfactory bulbs. CHEBI:22603 arabinoxylans biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22603 UBERON:0003037 septum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003037 septa A wall, dividing a cavity or structure into smaller ones[WP]. UBERON:0003028 commissure of inferior colliculus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003028 posterior colliculus commissure|commissure of caudal colliculus|inferior colliculus commissure|commissure of posterior corpus quadrigeminum|commissure of the inferior colliculi|caudal colliculus commissure|commissura colliculorum inferiorum|commissure of inferior colliculi|inferior collicular commissure|commissure of the inferior colliculus|commissura colliculorum caudalium|posterior corpus quadrigeminum commissure|commissura colliculi inferioris|commissure of posterior colliculus A commissure that is part of a inferior colliculus [Automatically generated definition]. CHEBI:22619 arginyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22619 UBERON:0003023 pontine tegmentum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003023 dorsal pons|dorsal portion of pons|tegmentum pontis|tegmentum pontis|pars dorsalis pontis|pars posterior pontis|tegmentum of pons|tegmental portion of pons Dorsal portion of the pons, containing cranial nervee nuclei, ascending and descending tracts and reticular nuclei. It is continuous with the reticular formation of the medulla (Carpenter, A Core Text of Neuroanatomy, 3rd ed, 1985, pg 133). CHEBI:22617 arginine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22617 UBERON:0003091 thyroid primordium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003091 thyroid primordia The initial thyroid precursor, the thyroid primordium, starts as a simple midline thickening and develops to form the thyroid diverticulum. This structure is initially hollow, although it later solidifies and becomes bilobed. The 2 lobes are located on either side of the midline and are connected via an isthmus. UBERON:0003098 optic stalk biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003098 optic stalks|pedunculus opticus the narrow, proximal portion of the optic vesicle which connects the embryonic eye and forebrain UBERON:0003099 cranial neural crest biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003099 head crest|head neural crest|cranial NCC population|crista neuralis cranialis|head NCC population|CNC|cephalic neural crest neural crest cells (NCCs) originating in the anterior part of the developing embryo and residing between the mid-diencephalon and the forming hindbrain; cranial NCCs migrate dorsolaterally to form the craniofacial mesenchyme that differentiates into various craniofacial cartilages and bones, cranial neurons, glia, and connective tissues of the face; these cells enter the pharyngeal pouches and arches where they give rise to thymic cells, bones of the middle ear and jaw (mandible), and the odontoblasts of the tooth primordia; like their counterparts in the trunk, cranial NCCs also contribute to the developing peripheral nervous system, along with the pigmented cell (i.e. melanocyte) lineage. UBERON:0003097 dorsal fin biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003097 nageoire dorsale@fr|notoptérygie@fr Median fin located on the dorsal surface of the organism. UBERON:0003080 anterior neural tube biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003080 CHEBI:71606 salvianin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71606 CHEBI:71608 cyclo(L-phenylalanyl-L-leucyl) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71608 CHEBI:71609 albonoursin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71609 UBERON:0003085 ventral aorta biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003085 The ventral aorta is a blood vessel in a single-pass circulatory system that carries de-oxygenated blood from the heart to the gills. In a single-pass circulatory system blood passes once through the heart to supply the body once[GO]. UBERON:0003086 caudal artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003086 CA Extension of the dorsal aorta in the tail. UBERON:0003083 trunk neural crest biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003083 TNC|trunk crest Trunk portion of the neural crest. The trunk neural crest lies between the vagal and sacral neural crest and gives rise to two groups of cells. One group migrates dorsolateral and populates the skin, forming pigment cells and the other migrates ventrolateral through the anterior sclerotome to become the epinephrine-producing cells of the adrenal gland and the neurons of the sympathetic nervous system. Some cells remain in the sclerotome to form the dorsal root ganglia [Wikipedia]. UBERON:0003084 heart primordium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003084 fused heart primordium|cardiac field Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline to form the heart rudiment or cone. UBERON:0003081 lateral plate mesoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003081 lateral mesoderm|lateral plate mesenchyme|mesoderma laminae lateralis|LPM|lateral plate Portion of the middle of the three primary germ layers of the embryo that resides on the periphery of the embryo, is continuous with the extra-embryonic mesoderm, splits into two layers enclosing the intra-embryonic coelom, and gives rise to body wall structures[MP]. UBERON:0003082 myotome biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003082 myotome region|myotomes|myomere|myotomus|myomeres|muscle plate A transitional population of migrating mesenchymal cells that derive from somites and that will become muscle cells. UBERON:0003089 sclerotome biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003089 sclerotomes|sclerotomus Ventral somitic compartment that is a precursor of the axial skeleton[XAO]. Sclerotomes eventually differentiate into the vertebrae and most of the skull. The caudal (posterior) half of one sclerotome fuses with the rostral (anterior) half of the adjacent one to form each vertebra. From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. From this vertebral body, sclerotome cells move dorsally and surround the developing spinal cord, forming the vertebral arch[WP]. CHEBI:71613 (25R)-Delta(4)-dafachronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71613 CHEBI:71616 (25S)-cholestenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71616 CHEBI:71618 cyclo(dehydrophenylalanyl-L-leucyl) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71618 CHEBI:71619 UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71619 UBERON:0003076 posterior neural tube biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003076 UBERON:0003077 paraxial mesoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003077 mesoderma paraxiale|paraxial mesenchyme|somitic mesoderm The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube[GO] UBERON:0003074 mesonephric duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003074 archinephric duct|Leydig's duct|ductus mesonephricus; ductus Wolffi|Wolffian duct|renal duct Paired organ that connects the primitive kidney Wolffian body (or mesonephros) to the cloaca and serves as the anlage for certain male reproductive organs. the Wolffian duct is what remains of the pronephric duct after the atrophy of the pronephros[WP]. In Zebrafish: Duct of the adult kidney (mesonephros), present bilaterally ventral to the somites and leading to the cloacal chamber[ZFA]. UBERON:0003075 neural plate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003075 lamina neuralis|presumptive central nervous system A region of embryonic ectodermal cells that lie directly above the notochord. During neurulation, they change shape and produce an infolding of the neural plate (the neural fold) that then seals to form the neural tube[XAO]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium[ZFA] UBERON:0003072 optic cup biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003072 eye cup|eyecup|ophtalmic cup|ocular cup Multi-tissue structure that is comprised of neural and non-neural epithelial layers which will form the retina and retinal pigmented epithelium of the mature eye[ZFA]. double walled structured formed by expansion and invagination of the distal end of the optic vesicle that develops into the pigmented and sensory layers of the retina while the mouth of the optic cup eventually forms the pupil of the eye[MP]. UBERON:0003073 lens placode biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003073 lens placodes|placoda lentis A thickened portion of ectoderm which serves as the precursor to the lens. SOX2 and Pou2f1 are involved in its development[WP]. UBERON:0003070 trigeminal placode complex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003070 trigeminal placodes|trigeminal placode|profundus placode|trigeminal V placode|profundus V placode A neurogenic placode that arises at the level of the midbrain-hindbrain boundary and develops into a trigeminal ganglion. UBERON:0003071 eye primordium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003071 optic placodes|occular primordium|optic placode of camera-type eye|ocular primordium|eye anlage|eye field|eye placode|optic field|optic placode|optic primordium Portion of tissue that is part of the anterior neural keel and will form the optic vesicle[ZFA]. A paired ectodermal placode that becomes invaginated to form the embryonic lens vesicles. UBERON:0003078 epibranchial placode biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003078 ventrolateral placode|epibranchial placodes Focal thickenings of the embryonic ectoderm that form immediately dorsal and caudal of the clefts between the pharyngeal arches and that produce the neuroblasts that migrate and condense to form the distal cranial ganglia. UBERON:0003079 floor plate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003079 floorplate|FP|bodenplatte|ventral plate The specialized glial structure (non-neuronal cells) situated at the ventral midline of the embryonic neural tube; this structure spans the anteroposterior axis from the midbrain to the tail regions, separating the left and right basal plates of the developing neural tube, and serves as an organizer to ventralize tissues in the embryo as well as to guide neuronal positioning and differentiation along the dorsoventral axis of the neural tube. CHEBI:71624 methanetelluronate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71624 UBERON:0003066 pharyngeal arch 2 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003066 second pharyngeal arch|hyoid bars|pharyngeal arch 2|2nd visceral arch|hyoid arch|2nd pharyngeal arch|branchial arch 2|second branchial arch|second visceral arch|arcus pharyngeus secundus|visceral arch 2|pharyngeal arches 2|2nd arch The second pharyngeal arch will form the hyoid apparatus. The cranial neural crest cells that populate the second pharyngeal arch emerge primarily from rhombomere 4 and will form skeletal elements. UBERON:0003063 prechordal plate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003063 head mesoderm|head mesenchyme A horseshoe-shaped thickening of the endoderm at the cranial (rostral) end of the primitive streak formed by the involution of Spemann's organizer cells which, together with the notochord, induces the formation of the neural plate from the overlying ectodermal cells and contributes mesodermal type cells to the surrounding tissue UBERON:0003064 intermediate mesoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003064 IM|intermediate plate mesoderm|mesenchyma intermedium|intermediate mesenchyme|intermediate plate The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads. UBERON:0003061 blood island biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003061 caudal hematopoietic tissue|blood islands|VBI|posterior blood island|ventral lateral plate mesoderm|ventral blood island|posterior ICM Blood islands are structures in the developing embryo which lead to many different parts of the circulatory system. They primarily derive from plexuses formed from angioblasts. Within them, vacuoles appear through liquefaction of the central part of the syncytium into plasma. The lumen of the blood vessels thus formed is probably intracellular. The flattened cells at the periphery form the endothelium. The nucleated red blood corpuscles develop either from small masses of the original angioblast left attached to the inner wall of the lumen or directly from the flat endothelial cells. In either case the syncytial mass thus formed projects from and is attached to the wall of the vessel. Such a mass is known as a blood island and hemoglobin gradually accumulates within it. Later the cells on the surface round up, giving the mass a mulberry-like appearance. Then the red blood cells break loose and are carried away in the plasma. Such free blood cells continue to divide. Blood islands have been seen in the area vasculosa in the omphalomesenteric vein and arteries, and in the dorsal aorta[WP, unvetted]. UBERON:0003062 primitive knot biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003062 Spemann Mangold organizer|embryo organizer|primitive node|nodus primitivus|node|Spemann's organizer|Hensen node|Henson's node|organizer|embryonic shield|DMZ|Hensen's node|shield|embryonic organizer|dorsal marginal zone organizer for gastrulation in vertebrates. The primitive knot starts as a regional knot of cells that forms on the blastodisc immediately anterior to where the outer layer of cells will begin to migrate inwards - an area known as the primitive streak. Posterior to the node is the primitive pit, where the cells of the epiblast (the upper layer of embryonic cells) initially begin to invaginate. This invagination expands posteriorly into the primitive groove as the cells layers continue to move into the space between the embryonic cells and the yolk. This differentiates the embryo into the germ layers - endoderm, mesoderm, and ectoderm. The primitive knot migrates posteriorly as gastrulation proceeds, eventually being absorbed into the tail bud.[WP]. the regional thickening of cells at the rostral tip of the vertebrate primitive streak through which gastrulating cells migrate anteriorally to form tissues in the future head and neck; this region organizes the formation of the three embryonic layers and establishes the longitudinal axis and the polarity of the embryo[MP]. UBERON:0003060 pronephric duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003060 pronephric ducts|archinephric duct|ductus pronephricus In mammals, the pronephric duct is the predecessor of the Wolffian duct[WP]. UBERON:0003069 otic placode biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003069 auditory placode|ear/otic placode|ear placode|octaval VIII placode|placoda otica|octaval placode A cranial placode which, once specified, invaginates to form an otic cup, which eventually separates from the surface ectoderm to form the otic vesicle or otocyst, a rounded structure without appar- ent polarity. As the otic placode invaginates into a cup neuroblasts delaminate from the anterior ventral aspect of the otic epithelium to give rise to neurons of the vestibulocochlear (statoacoustic) ganglion of cranial nerve VIII[NBK] UBERON:0003067 dorsolateral placode biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003067 dorsolateral placodes Lateral neurogenic placodes positioned dorsal of the epibranchial placodes. UBERON:0003068 axial mesoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003068 chordamesoderm The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord. GO:0006429 leucyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006429 The process of coupling leucine to leucyl-tRNA, catalyzed by leucyl-tRNA synthetase. The leucyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a leucine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification. GO:0006427 histidyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006427 The process of coupling histidine to histidyl-tRNA, catalyzed by histidyl-tRNA synthetase. The histidyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3''-OH group of a histidine-accetping tRNA. GO:0006428 isoleucyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006428 The process of coupling isoleucine to isoleucyl-tRNA, catalyzed by isoleucyl-tRNA synthetase. The isoleucyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a isoleucine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification. GO:0006425 glutaminyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006425 The process of coupling glutamine to glutaminyl-tRNA, catalyzed by glutaminyl-tRNA synthetase. The glutaminyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a glutamine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification. GO:0006426 glycyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006426 The process of coupling glycine to glycyl-tRNA, catalyzed by glycyl-tRNA synthetase. The glycyll-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a glycine-accepting tRNA. GO:0006423 cysteinyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006423 The process of coupling cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. A cysteinyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a cysteine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification. GO:0006424 glutamyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006424 The process of coupling glutamate to glutamyl-tRNA, catalyzed by glutamyl-tRNA synthetase. The glutamyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a glutamic acid-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification. UBERON:0017615 vomerine dentition biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0017615 vomerine teeth A set of teeth in which each tooth that attaches to a vomer. GO:0006421 asparaginyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006421 The process of coupling asparagine to asparaginyl-tRNA, catalyzed by asparaginyl-tRNA synthetase. The asparaginyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of an asparagine-accetping tRNA. GO:0006422 aspartyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006422 The process of coupling aspartate to aspartyl-tRNA, catalyzed by aspartyl-tRNA synthetase. The aspartyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of an aspartic acid accetping tRNA. GO:0006420 arginyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006420 The process of coupling arginine to arginyl-tRNA, catalyzed by arginyl-tRNA synthetase. The arginyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of an alanine accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification. CHEBI:32023 plaunotol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32023 CHEBI:4638 diphenidol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_4638 CHEBI:46662 mineral biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46662 GO:0006438 valyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006438 The process of coupling valine to valyl-tRNA, catalyzed by valyl-tRNA synthetase. The valyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a valine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification. GO:0006439 obsolete aminoacyl-tRNA hydrolase reaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006439 aminoacyl-tRNA hydrolase reaction OBSOLETE. Hydrolysis of the peptidyl-tRNA by aminoacyl-tRNA hydrolase upon termination of translation. Analogous to usual peptidyl transfer during elongation, except that the acceptor is H2O instead of an aminoacyl-tRNA. GO:0006436 tryptophanyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006436 The process of coupling tryptophan to tryptophanyl-tRNA, catalyzed by tryptophanyl-tRNA synthetase. The tryptophanyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a tryptophan-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification. GO:0006437 tyrosyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006437 The process of coupling tyrosine to tyrosyl-tRNA, catalyzed by tyrosyl-tRNA synthetase. The tyrosyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a tyrosine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification. GO:0006434 seryl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006434 The process of coupling serine to seryl-tRNA, catalyzed by seryl-tRNA synthetase. The seryl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a serine-accetping tRNA. CHEBI:46668 amino acid ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46668 GO:0006435 threonyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006435 The process of coupling threonine to threonyl-tRNA, catalyzed by threonyl-tRNA synthetase. The threonyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a threonine-accetping tRNA. GO:0006432 phenylalanyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006432 The process of coupling phenylalanine to phenylalanyl-tRNA, catalyzed by phenylalanyl-tRNA synthetase. The phenylalanyl-tRNA synthetase is a class-II synthetase. However, unlike other class II enzymes, The activated amino acid is transferred to the 2'-OH group of a phenylalanine-accepting tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification. GO:0006433 prolyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006433 The process of coupling proline to prolyl-tRNA, catalyzed by prolyl-tRNA synthetase. The prolyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a methionine-accetping tRNA. GO:0006430 lysyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006430 The process of coupling lysine to lysyl-tRNA, catalyzed by lysyl-tRNA synthetase. The lysyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a lysine-accetping tRNA. GO:0006431 methionyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006431 The process of coupling methionine to methionyl-tRNA, catalyzed by methionyl-tRNA synthetase. The methionyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a methionine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification. CHEBI:4648 hop-22(29)-ene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_4648 GO:0006407 rRNA export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006407 rRNA export out of nucleus|rRNA-nucleus export|rRNA export from cell nucleus|rRNA transport from nucleus to cytoplasm The directed movement of rRNA from the nucleus to the cytoplasm; the rRNA is usually in the form of ribonucleoproteins. GO:0006408 snRNA export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006408 snRNA transport from nucleus to cytoplasm|snRNA export from cell nucleus|snRNA export out of nucleus|snRNA-nucleus export The directed movement of snRNA from the nucleus to the cytoplasm. GO:0006405 RNA export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006405 RNA export from cell nucleus|RNA transport from nucleus to cytoplasm|RNA export out of nucleus|RNA-nucleus export The directed movement of RNA from the nucleus to the cytoplasm. CHEBI:22682 azobenzenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22682 GO:0006406 mRNA export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006406 mRNA export out of nucleus|mRNA-nucleus export|mRNA transport from nucleus to cytoplasm|mRNA export from cell nucleus The directed movement of mRNA from the nucleus to the cytoplasm. GO:0006403 RNA localization biolink:BiologicalProcess go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0006403 establishment and maintenance of RNA localization|RNA localisation A process in which RNA is transported to, or maintained in, a specific location. GO:0006404 RNA import into nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006404 RNA-nucleus import|RNA import into cell nucleus|RNA transport from cytoplasm to nucleus The import of RNA from the cytoplasm to the nucleus. GO:0006401 RNA catabolic process biolink:BiologicalProcess go-plus goslim_yeast|goslim_drosophila http://purl.obolibrary.org/obo/GO_0006401 RNA degradation|RNA catabolism|RNA breakdown The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. GO:0006402 mRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006402 mRNA degradation|mRNA breakdown|mRNA catabolism|mRNA decay The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes. GO:0006400 tRNA modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006400 tRNA editing The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically. GO:0006409 tRNA export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006409 tRNA-nucleus export|tRNA export out of nucleus|tRNA export from cell nucleus|tRNA transport from nucleus to cytoplasm The directed movement of tRNA from the nucleus to the cytoplasm. GO:0006418 tRNA aminoacylation for protein translation biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0006418 MetaCyc:TRNA-CHARGING-PWY tRNA charging The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, to be used in ribosome-mediated polypeptide synthesis. CHEBI:46640 diketone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46640 CHEBI:22695 base biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22695 GO:0006419 alanyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006419 The process of coupling alanine to alanyl-tRNA, catalyzed by alanyl-tRNA synthetase. The alanyl-tRNA synthetase is a class-II synthetases. The activated amino acid is transferred to the 3'-OH group of an alanine accetping tRNA. GO:0006416 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006416 CHEBI:22693 barbiturates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22693 GO:0006417 regulation of translation biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0006417 regulation of protein anabolism|regulation of protein synthesis|regulation of protein formation|regulation of protein biosynthesis Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA. GO:0006414 translational elongation biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0006414 translation elongation|protein synthesis elongation The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis. CHEBI:46644 D-altronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46644 GO:0006415 translational termination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006415 translational complex disassembly|translation termination|protein synthesis termination The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code). CHEBI:46645 isobutanol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46645 GO:0006412 translation biolink:BiologicalProcess go-plus goslim_candida|goslim_plant|goslim_pir|goslim_aspergillus|goslim_metagenomics|goslim_generic|goslim_chembl http://purl.obolibrary.org/obo/GO_0006412 Wikipedia:Translation_(genetics) protein biosynthetic process|protein biosynthesis|protein anabolism|protein synthesis|protein formation|protein translation The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome. GO:0006413 translational initiation biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0006413 translation initiation|biopolymerisation|protein synthesis initiation|biopolymerization The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA. CHEBI:22698 benzaldehydes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22698 GO:0006410 obsolete transcription, RNA-dependent biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006410 transcription, RNA-dependent OBSOLETE. The cellular synthesis of DNA on a template of RNA. GO:0006411 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006411 CHEBI:4629 diosgenin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_4629 CHEBI:22691 barbiturate anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22691 CHEBI:4623 (carboxymethyl)(dimethyl)sulfonium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_4623 UBERON:0017651 salivary gland primordium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0017651 A primordium that has the potential to develop into a saliva-secreting gland. CHEBI:22660 aspartic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22660 UBERON:0017650 developing mesenchymal structure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0017650 A mesenchyme-derived anatomical entity undergoing a transtion to become another structure. CHEBI:22661 aspartic acid derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22661 CHEBI:46633 carbapenems biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46633 CHEBI:46634 carbapenemcarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46634 UBERON:0017659 ventral surface of penis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0017659 urethral surface of penis CHEBI:4676 dodecanedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_4676 CHEBI:46638 O-sinapoyl-D-glucaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46638 CHEBI:22669 aspulvinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22669 CHEBI:4672 docetaxel anhydrous biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_4672 CHEBI:22676 auxin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22676 UBERON:0017648 ventral body wall biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0017648 anterior body wall The ventral part of the body wall UBERON:0017649 dorsal body wall biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0017649 The dorsal part of the body wall CHEBI:46629 oxo group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46629 CHEBI:46611 phosphorothioic O,O,O-acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46611 CHEBI:22644 arylalkylamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22644 CHEBI:46612 phosphorothioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46612 CHEBI:22645 arenecarboxamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22645 CHEBI:46613 phosphorothioic O,O,S-acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46613 UBERON:0017628 swim bladder gas gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0017628 red gland|fascis mirabilis|red gland of gas bladder|gas gland A structure with numerous blood vessels (retia mirabilia) in the gas bladder that secretes gases from the blood. CHEBI:22648 arylmercury compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22648 CHEBI:22651 ascorbate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22651 CHEBI:22652 ascorbic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22652 CHEBI:22656 asparaginyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_22656 CHEBI:22653 asparagine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22653 CHEBI:22654 asparagine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22654 CHEBI:22658 aspartate family amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22658 GO:0031588 nucleotide-activated protein kinase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031588 5'-AMP-activated protein kinase complex|SNF1/AMPK protein kinase complex|ADP-activated protein kinase complex|AMPK complex|Snf1 kinase complex|Snf1 serine/threonine protein kinase complex|AMP-activated protein kinase complex A protein complex that possesses nucleotide-dependent protein kinase activity. The nucleotide can be AMP (in S. pombe and human) or ADP (in S. cerevisiae). GO:0031589 cell-substrate adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031589 The attachment of a cell to the underlying substrate via adhesion molecules. GO:0031586 negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031586 downregulation of IP3 receptor activity|negative regulation of inositol 1,4,5-trisphosphate receptor activity|down-regulation of IP3 receptor activity|inhibition of IP3 receptor activity|negative regulation of IP3 receptor activity|down regulation of IP3 receptor activity Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel. GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031587 positive regulation of inositol-1,4,5-trisphosphate receptor activity|up regulation of IP3 receptor activity|activation of IP3 receptor activity|stimulation of IP3 receptor activity|up-regulation of IP3 receptor activity|positive regulation of IP3 receptor activity|upregulation of IP3 receptor activity Any process that activates or increases the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel. CHEBI:136282 9-[(9Z)-octadecenoyloxy]octadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136282 GO:0031584 activation of phospholipase D activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031584 Any process that initiates the activity of inactive phospholipase D. GO:0031585 regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031585 regulation of IP3 receptor activity|regulation of inositol-1,4,5-triphosphate receptor activity Any process that modulates the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel. CHEBI:4470 dextromethorphan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_4470 GO:0031582 replication fork arrest at rDNA repeats biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031582 replication fork blocking at rDNA repeats|replication fork arrest at ribosomal DNA repeats A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the eukaryotic rDNA repeat spacer. GO:0031583 phospholipase D-activating G protein-coupled receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031583 phospholipase D-activating G-protein coupled receptor signaling pathway|G-protein signalling, phospholipase D activating pathway|activation of phospholipase D activity by G-protein coupled receptor protein signaling pathway The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase D (PLD) and a subsequent increase in cellular levels of phosphatidic acid (PA). GO:0031580 membrane raft distribution biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031580 lipid raft distribution The process that establishes the spatial arrangement of membrane rafts within a cellular membrane. CHEBI:136286 9-hydroxyoctadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136286 GO:0031581 hemidesmosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031581 Assembly of hemidesmosomes, integrin-containing protein complexes that bind to laminin in the basal lamina. Hemidesmosomes form the contact between the basal surface of epithelial cells and the underlying basal lamina. GO:0031579 membrane raft organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031579 membrane raft organization and biogenesis|membrane raft organisation|lipid raft organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of membrane rafts, small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. GO:0031577 spindle checkpoint biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0031577 Wikipedia:Spindle_checkpoint A cell cycle checkpoint that originates from the mitotic or meiotic spindle. GO:0031578 mitotic spindle orientation checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031578 spindle position checkpoint|SPOC|mitotic cell cycle spindle orientation checkpoint|SOC A cell cycle checkpoint that monitors and signals errors in the placement or orientation of the spindle in the cell. This delays the completion of anaphase until errors are corrected. GO:0031575 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031575 GO:0031576 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031576 GO:0031573 intra-S DNA damage checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031573 S-phase checkpoint|mitotic intra-S DNA damage checkpoint A mitotic cell cycle checkpoint that slows DNA synthesis in response to DNA damage by the prevention of new origin firing and the stabilization of slow replication fork progression. GO:0031574 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031574 GO:0031571 mitotic G1 DNA damage checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031571 mitotic cell cycle G1/S transition DNA damage checkpoint A mitotic cell cycle checkpoint that detects and negatively regulates progression through the G1/S transition of the cell cycle in response to DNA damage. GO:0031572 G2 DNA damage checkpoint biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0031572 G2/M transition DNA damage checkpoint A cell cycle checkpoint that detects and negatively regulates progression from G2 to M phase in the cell cycle in response to DNA damage. GO:0031570 DNA integrity checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031570 A cell cycle process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and progresses through signal transduction and ends with cell cycle effector processes. GO:0031568 G1 cell size control checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031568 mitotic cell cycle G1/S transition size control checkpoint|mitotic G1 cell size control checkpoint A mitotic cell cycle checkpoint that monitors cell size, and negatively regulates cell cycle progression between G1 and S phase until a critical size is reached. GO:0031569 mitotic G2 cell size control checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031569 mitotic cell cycle G2/M transition size control checkpoint|G2 cell size control checkpoint|G2/M transition size control checkpoint A mitotic cell cycle checkpoint that monitors cell size, and negatively regulates cell cycle progression between G2 and M phase until a critical size is reached. GO:0031566 actomyosin contractile ring maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031566 contractile ring maintenance involved in cell cycle cytokinesis|cytokinesis, contractile ring maintenance, involved in cytokinesis during cell cycle The cell cycle process in which the contractile ring is maintained in response to the cytokinesis checkpoint; that is when cytokinesis is delayed awaiting completion of nuclear division or the correct formation of cytokinetic structures. This process occurs in the context of cytokinesis that takes place as part of a cell cycle. GO:0031567 mitotic cell size control checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031567 mitotic cell cycle cell size control checkpoint The mitotic cell cycle checkpoint that delays or arrests cell cycle progression until cells have reached a critical size. GO:0031564 transcription antitermination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031564 transcriptional readthrough Regulation of transcription by a mechanism that allows RNA polymerase to continue transcription beyond termination site(s). PR:000017283 vitamin D3 receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000017283 NR1I1|VDR|1,25-dihydroxyvitamin D3 receptor|nuclear receptor subfamily 1 group I member 1 A protein that is a translation product of the human VDR gene or a 1:1 ortholog thereof. GO:0031565 obsolete cytokinesis checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031565 septin checkpoint|contractile ring checkpoint OBSOLETE. A mitotic cell cycle checkpoint that detects a defect in cytokinesis and negatively regulates G2/M transition. GO:0031562 hyphal tip polarisome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031562 Protein complex that has a role in determining cell polarity, found at the tip of a growing fungal hypha. GO:0031563 mating projection tip polarisome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031563 Protein complex that has a role in determining cell polarity, found at the tip of the mating projection in unicellular fungi exposed to mating pheromone. GO:0031560 cellular bud neck polarisome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031560 Protein complex that has a role in determining cell polarity, found at the neck of a fungal bud before and during cytokinesis. GO:0031561 cellular bud tip polarisome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031561 Protein complex that has a role in determining cell polarity, found at the tip of a growing fungal bud. GO:0031559 oxidosqualene cyclase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031559 2,3-oxidosqualene cyclase activity Catalysis of the cyclization of (S)-2,3-epoxysqualene to form a triterpene. GO:0031557 obsolete induction of programmed cell death in response to chemical stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031557 induction of programmed cell death in response to chemical substance|induction of programmed cell death in response to chemical stimulus OBSOLETE. A process which directly activates any of the steps required for programmed cell death as a result of a chemical stimulus. GO:0031558 obsolete induction of apoptosis in response to chemical stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031558 induction of apoptosis in response to chemical stimulus|induction of apoptosis in response to chemical substance OBSOLETE. Any process that directly activates any of the steps required for cell death by apoptosis as a result of a chemical stimulus. GO:0031555 transcriptional attenuation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031555 Wikipedia:Attenuator_(genetics) Regulation of transcription through variation in where transcription termination occurs. GO:0031556 transcriptional attenuation by ribosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031556 ribosome-mediated transcriptional attenuation A type of transcriptional regulation at the level of early termination. This process can occur only in prokaryotes, where transcription of an operon into messenger RNA and translation of that mRNA into polypeptides occur simultaneously. The general principle is that alternative mRNA secondary structures occur under different physiological conditions such as available amount of a particular amino acid. One set of conditions favors early termination of transcription. In the classic example of the trp biosynthesis operon, translation of the gene for a short, trp-containing polypeptide called the trp operon leader peptide pauses either at a trp codon (if tryptophan is scarce) or the stop codon (if trp is readily available). In the former situation transcription continues, but in the latter a Rho-independent terminator forms and reduces, or attenuates, expression of the tryptophan biosynthesis genes. Although the polypeptides encoded by leader peptide genes appear not to be stable once their translation is complete, it is suggested by recent studies that their nascent polypeptide chains interact specifically with ribosomes, specific uncharged tRNAs, or other cellular components to inhibit release at the stop codon and improve the function of transcriptional attenuation as a regulatory switch. CHEBI:4469 (S)-amphetamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_4469 PR:000017272 vinculin biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000017272 VCL|metavinculin A protein that is a translation product of the human VCL gene or a 1:1 ortholog thereof. GO:0031553 positive regulation of brain-derived neurotrophic factor-activated receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031553 up-regulation of brain-derived neurotrophic factor receptor activity|upregulation of brain-derived neurotrophic factor receptor activity|positive regulation of brain-derived neurotrophic factor receptor activity|up regulation of brain-derived neurotrophic factor receptor activity|positive regulation of BDNF receptor activity|activation of brain-derived neurotrophic factor receptor activity|stimulation of brain-derived neurotrophic factor receptor activity Any process that activates or increases the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity. GO:0031554 regulation of DNA-templated transcription, termination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031554 regulation of termination of DNA-dependent transcription|regulation of DNA-dependent transcription, termination|transcription antiterminator activity|regulation of transcription termination, DNA-dependent Any process that modulates the frequency, rate, extent, or location of DNA-templated transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA. GO:0031551 regulation of brain-derived neurotrophic factor-activated receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031551 regulation of brain-derived neurotrophic factor receptor activity|regulation of BDNF receptor activity Any process that modulates the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity. GO:0031552 negative regulation of brain-derived neurotrophic factor-activated receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031552 inhibition of brain-derived neurotrophic factor receptor activity|down regulation of brain-derived neurotrophic factor receptor activity|negative regulation of BDNF receptor activity|downregulation of brain-derived neurotrophic factor receptor activity|negative regulation of brain-derived neurotrophic factor receptor activity|down-regulation of brain-derived neurotrophic factor receptor activity Any process that stops, prevents, or reduces the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity. GO:0031550 positive regulation of brain-derived neurotrophic factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031550 stimulation of brain-derived neurotrophic factor receptor signaling pathway|up-regulation of brain-derived neurotrophic factor receptor signaling pathway|activation of brain-derived neurotrophic factor receptor signaling pathway|positive regulation of BDNF receptor signaling pathway|up regulation of brain-derived neurotrophic factor receptor signaling pathway|upregulation of brain-derived neurotrophic factor receptor signaling pathway|positive regulation of BDNF receptor signalling pathway|positive regulation of brain-derived neurotrophic factor receptor signalling pathway Any process that activates or increases the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway. GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031548 regulation of BDNF receptor signaling pathway|regulation of brain-derived neurotrophic factor receptor signalling pathway|regulation of BDNF receptor signalling pathway Any process that modulates the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway. GO:0031549 negative regulation of brain-derived neurotrophic factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031549 down-regulation of brain-derived neurotrophic factor receptor signaling pathway|negative regulation of BDNF receptor signaling pathway|downregulation of brain-derived neurotrophic factor receptor signaling pathway|down regulation of brain-derived neurotrophic factor receptor signaling pathway|negative regulation of BDNF receptor signalling pathway|inhibition of brain-derived neurotrophic factor receptor signaling pathway|negative regulation of brain-derived neurotrophic factor receptor signalling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway. GO:0031546 brain-derived neurotrophic factor receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031546 BDNF receptor binding|brain-derived neurotrophic factor ligand Interacting selectively and non-covalently with the brain-derived neurotrophic factor receptor. GO:0031547 brain-derived neurotrophic factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031547 BDNF signalling pathway|BDNF receptor signaling pathway|brain-derived neurotrophic factor receptor signalling pathway The series of molecular signals generated as a consequence of a brain-derived neurotrophic factor receptor binding to one of its physiological ligands. GO:0006588 activation of tryptophan 5-monooxygenase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006588 tryptophan hydroxylase activation The process in which the tryptophan 5-monooxygenase enzyme is changed so that it can carry out its enzymatic activity. GO:0031544 peptidyl-proline 3-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031544 Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl trans-3-hydroxy-L-proline + succinate + CO2. GO:0006589 octopamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006589 octopamine synthesis|octopamine formation|octopamine biosynthesis|octopamine anabolism The chemical reactions and pathways resulting in the formation of octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol. The D enantiomer is about one-tenth as active as norepinephrine and is found in the salivary glands of Octopus and Eledone species. GO:0031545 peptidyl-proline 4-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031545 Reactome:R-HSA-1234181|Reactome:R-HSA-1234179|Reactome:R-HSA-1234177|Reactome:R-HSA-1234173|Reactome:R-HSA-1234166|Reactome:R-HSA-1234165 prolyl 4-hydroxylase|HIF-type prolyl 4-hydroxylase Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl trans-4-hydroxy-L-proline + succinate + CO2. GO:0006586 indolalkylamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006586 indolamine metabolism|indolamine metabolic process|indolalkylamine metabolism The chemical reactions and pathways involving indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group. GO:0006587 serotonin biosynthetic process from tryptophan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006587 serotonin formation from tryptophan|serotonin anabolism from tryptophan|serotonin synthesis from tryptophan The chemical reactions and pathways resulting in the formation from tryptophan of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. GO:0006584 catecholamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006584 catecholamine metabolism The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. GO:0006585 dopamine biosynthetic process from tyrosine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006585 dopamine formation from tyrosine|dopamine anabolism from tyrosine|dopamine synthesis from tyrosine The chemical reactions and pathways resulting in the formation of dopamine (3,4-dihydroxyphenylethylamine) from L-tyrosine, via the metabolic precursor 3,4-dihydroxy-L-phenylalanine (L-dopa). Dopamine is a catecholamine neurotransmitter and a metabolic precursor of norepinephrine and epinephrine. GO:0006582 melanin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006582 melanin metabolism The chemical reactions and pathways involving melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom. GO:0006583 melanin biosynthetic process from tyrosine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006583 melanin anabolism from tyrosine|melanin synthesis from tyrosine|melanin formation from tyrosine The chemical reactions and pathways resulting in the formation of melanin from other compounds, including tyrosine. GO:0006580 ethanolamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006580 ethanolamine metabolism The chemical reactions and pathways involving ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine). GO:0006581 acetylcholine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006581 acetylcholine degradation|acetylcholine breakdown|acetylcholine catabolism The chemical reactions and pathways resulting in the breakdown of acetylcholine, the acetic acid ester of the organic base choline. GO:0006590 thyroid hormone generation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006590 The formation of either of the compounds secreted by the thyroid gland, mainly thyroxine and triiodothyronine. This is achieved by the iodination and joining of tyrosine molecules to form the precursor thyroglobin, proteolysis of this precursor gives rise to the thyroid hormones. GO:0031542 positive regulation of anthocyanin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031542 positive regulation of anthocyanin biosynthesis|positive regulation of anthocyanin synthesis|up regulation of anthocyanin biosynthetic process|positive regulation of anthocyanin formation|upregulation of anthocyanin biosynthetic process|stimulation of anthocyanin biosynthetic process|up-regulation of anthocyanin biosynthetic process|activation of anthocyanin biosynthetic process|positive regulation of anthocyanin anabolism Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins. GO:0031543 peptidyl-proline dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031543 prolyl hydroxylase activity|prolyl 4-hydroxylase activity|proline,2-oxoglutarate 4-dioxygenase activity|proline hydroxylase activity Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl hydroxy-L-proline + succinate + CO2. GO:0031540 regulation of anthocyanin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031540 regulation of anthocyanin biosynthesis|regulation of anthocyanin anabolism|regulation of anthocyanin synthesis|regulation of anthocyanin formation Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins. GO:0031541 negative regulation of anthocyanin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031541 negative regulation of anthocyanin anabolism|negative regulation of anthocyanin synthesis|downregulation of anthocyanin biosynthetic process|negative regulation of anthocyanin formation|down regulation of anthocyanin biosynthetic process|inhibition of anthocyanin biosynthetic process|negative regulation of anthocyanin biosynthesis|down-regulation of anthocyanin biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins. CHEBI:136243 phosphatidylinositol 34:2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136243 GO:0031539 positive regulation of anthocyanin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031539 up regulation of anthocyanin metabolic process|activation of anthocyanin metabolic process|stimulation of anthocyanin metabolic process|up-regulation of anthocyanin metabolic process|positive regulation of anthocyanin metabolism|upregulation of anthocyanin metabolic process Any process that activates or increases the frequency, rate or extent of chemical reactions and pathways involving anthocyanins. GO:0031537 regulation of anthocyanin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031537 regulation of anthocyanin metabolism Any process that modulates the frequency, rate or extent of chemical reactions and pathways involving anthocyanins. GO:0031538 negative regulation of anthocyanin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031538 downregulation of anthocyanin metabolic process|down-regulation of anthocyanin metabolic process|inhibition of anthocyanin metabolic process|negative regulation of anthocyanin metabolism|down regulation of anthocyanin metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving anthocyanins. GO:0031535 plus-end directed microtubule sliding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031535 The movement of one microtubule along another microtubule, where the motion is directed towards the plus ends of the microtubules. GO:0031536 positive regulation of exit from mitosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031536 upregulation of exit from mitosis|up regulation of exit from mitosis|activation of exit from mitosis|stimulation of exit from mitosis|up-regulation of exit from mitosis Any process that activates or increases the rate of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity). GO:0031533 mRNA cap methyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031533 mRNA (guanine-N7) methyltransferase complex|mRNA capping enzyme complex A protein complex that consists of an RNA 5' triphosphatase and a guanyl transferase (Cet1p and Ceg1p in S. cerevisiae; Pct1 and Ceg1 in S. pombe) and is involved in mRNA capping. GO:0006599 phosphagen metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006599 phosphagen metabolism The chemical reactions and pathways involving phosphagen, any of a group of guanidine phosphates that occur in muscle and can be used to regenerate ATP from ADP during muscular contraction. GO:0031534 minus-end directed microtubule sliding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031534 The movement of one microtubule along another microtubule, where the motion is directed towards the minus ends of the microtubules. GO:0006597 spermine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006597 spermine anabolism|spermine synthesis|spermine biosynthesis|spermine formation The chemical reactions and pathways resulting in the formation of spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses and involved in nucleic acid packaging. GO:0006598 polyamine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006598 polyamine degradation|polyamine breakdown|polyamine catabolism The chemical reactions and pathways resulting in the breakdown of polyamines, any organic compound containing two or more amino groups. GO:0006595 polyamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006595 polyamine metabolism The chemical reactions and pathways involving polyamines, any organic compound containing two or more amino groups. GO:0006596 polyamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006596 MetaCyc:POLYAMSYN-PWY polyamine biosynthesis|polyamine anabolism|polyamine synthesis|polyamine formation The chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups. GO:0006593 ornithine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006593 ornithine degradation|ornithine breakdown|ornithine catabolism The chemical reactions and pathways resulting in the breakdown of ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis. GO:0006594 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006594 GO:0006591 ornithine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006591 ornithine metabolism The chemical reactions and pathways involving ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis. GO:0006592 ornithine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006592 ornithine anabolism|ornithine synthesis|ornithine formation|ornithine biosynthesis The chemical reactions and pathways resulting in the formation of ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis. CHEBI:136257 phosphatidylserine 36:2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136257 GO:0031531 thyrotropin-releasing hormone receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031531 thyrotropin-releasing hormone receptor ligand|thyrotropin releasing hormone receptor binding Interacting selectively and non-covalently with a receptor for thyrotropin-releasing hormone, a tripeptide hormone that is produced by the hypothalamus and stimulates the release of thyroid-stimulating hormone (TSH) and prolactin by the anterior pituitary. GO:0031532 actin cytoskeleton reorganization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031532 actin cytoskeleton reorganisation|actin cytoskeleton remodeling A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of constituent parts of cytoskeletal structures comprising actin filaments and their associated proteins. GO:0031530 gonadotropin-releasing hormone receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031530 gonadotrophin-releasing hormone receptor binding|GnRH receptor binding Interacting selectively and non-covalently with a receptor for gonadotropin-releasing hormone (GnRH), a peptide hormone that is synthesized and released by the hypothalamus and is responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. CHEBI:136256 phosphatidylserine 36:1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136256 GO:0031528 microvillus membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031528 The portion of the plasma membrane surrounding a microvillus. GO:0031529 ruffle organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031529 ruffle organization and biogenesis|ruffle organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ruffle, a projection at the leading edge of a crawling cell. GO:0031526 brush border membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031526 The portion of the plasma membrane surrounding the brush border. GO:0031527 filopodium membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031527 The portion of the plasma membrane surrounding a filopodium. GO:0031524 menthol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031524 menthol metabolism The chemical reactions and pathways involving menthol, the monoterpene 2-isopropyl-5-methylcyclohexanol. GO:0006568 tryptophan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006568 Wikipedia:Tryptophan tryptophan metabolism The chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid. GO:0031525 menthol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031525 menthol biosynthesis|menthol anabolism|menthol synthesis|menthol formation The chemical reactions and pathways resulting in the formation of menthol, the monoterpene 2-isopropyl-5-methylcyclohexanol. GO:0006569 tryptophan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006569 tryptophan catabolic process, using tryptophanase|tryptophan degradation|tryptophan catabolism|tryptophan catabolism, using tryptophanase|tryptophan breakdown The chemical reactions and pathways resulting in the breakdown of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid. GO:0006566 threonine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006566 UM-BBD_pathwayID:met methionine and threonine metabolism|threonine metabolism|methionine and threonine metabolic process The chemical reactions and pathways involving threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins. GO:0031522 cell envelope Sec protein transport complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031522 plasma membrane Sec complex|Sec translocation complex|Sec secretion complex|Sec complex A transmembrane protein complex involved in the translocation of proteins across the cytoplasmic membrane. In Gram-negative bacteria, Sec-translocated proteins are subsequently secreted via the type II, IV, or V secretion systems. Sec complex components include SecA, D, E, F, G, Y and YajC. GO:0006567 threonine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006567 MetaCyc:THREOCAT-PWY|UM-BBD_pathwayID:met threonine degradation|threonine breakdown|threonine catabolism The chemical reactions and pathways resulting in the breakdown of threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins. GO:0031523 Myb complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031523 Myeloblastosis proto-oncogene protein complex A multisubunit complex consisting of Myb and other proteins that regulates site specific DNA replication, gene amplification and transcriptional repression. GO:0006564 L-serine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006564 MetaCyc:SERSYN-PWY L-serine anabolism|L-serine synthesis|L-serine formation|L-serine biosynthesis The chemical reactions and pathways resulting in the formation of L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid. GO:0006565 L-serine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006565 MetaCyc:SERDEG-PWY L-serine degradation|L-serine breakdown|L-serine catabolism The chemical reactions and pathways resulting in the breakdown of L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid. GO:0006562 proline catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006562 proline degradation|proline breakdown|proline catabolism The chemical reactions and pathways resulting in the breakdown of proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins. GO:0006563 L-serine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006563 L-serine metabolism The chemical reactions and pathways involving L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid. GO:0006560 proline metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006560 proline metabolism The chemical reactions and pathways involving proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins. GO:0006561 proline biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006561 MetaCyc:PROSYN-PWY|MetaCyc:PWY-3341 proline anabolism|proline synthesis|proline formation|proline biosynthesis The chemical reactions and pathways resulting in the formation of proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins. GO:0031520 plasma membrane of cell tip biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031520 'plasma membrane, cell tip' The portion of the plasma membrane surrounding the cell tip. GO:0031521 spitzenkorper biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031521 Structure within the hyphal tip of filamentous fungi that acts as an organizing center for hyphal tip growth; may function to supply vesicles to the elongating tip and/or to organize cytoskeletal microfilaments. CHEBI:136220 phosphatidylglycerol 32:1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136220 GO:0031517 red light photoreceptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031517 The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 660nm. The response may involve a change in conformation. GO:0031518 CBF3 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031518 A multisubunit protein complex that binds to centromeric DNA and initiates kinetochore assembly. In yeast, this complex consists of four subunits, namely Ctf13p, Skp1p, Cep3p and Cbf2p. GO:0031515 tRNA (m1A) methyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031515 A protein complex involved in the catalysis of the formation of the modified nucleotide 1-methyladenosine (m1A) in tRNA. In yeast, it is a heterotetramer of two subunits, Gcd10p and Gcd14p, while in bacteria and archaea it is a homotetramer. GO:0031516 far-red light photoreceptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031516 The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 730nm. The response may involve a change in conformation. GO:0031513 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031513 GO:0006579 amino-acid betaine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006579 betaine degradation|betaine breakdown|betaine catabolic process|betaine catabolism The chemical reactions and pathways resulting in the breakdown of any betaine, the N-trimethyl derivative of an amino acid. GO:0031514 motile cilium biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031514 motile primary cilium|microtubule-based flagellum|motile secondary cilium|motile cilia|motile primary cilia|nodal cilium A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell. GO:0006577 amino-acid betaine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006577 betaine metabolism|betaine metabolic process The chemical reactions and pathways involving any betaine, the N-trimethyl derivative of an amino acid. GO:0031511 Mis6-Sim4 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031511 Mis6 centromere subcomplex|Mis6-Mal2-Sim4 centromere complex|Sim4 complex A protein complex that forms part of the inner centromere, which is involved in the loading of the centromeric histone h3 variant CENP-A onto centromeres and in centromere specific heterochromatin formation. The complex contains about 12 proteins, of which two are known as Mis6 and Sim4 in S. pombe and CENP-I and CENP-H in human. GO:0031512 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031512 GO:0006578 amino-acid betaine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006578 betaine anabolism|betaine synthesis|betaine formation|betaine biosynthesis|betaine biosynthetic process The chemical reactions and pathways resulting in the formation of any betaine, the N-trimethyl derivative of an amino acid. GO:0006575 cellular modified amino acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006575 cellular amino acid derivative metabolism|modified amino acid metabolic process|cellular amino acid derivative metabolic process|modified amino acid metabolism|amino acid derivative metabolic process|cellular modified amino acid metabolism The chemical reactions and pathways involving compounds derived from amino acids, organic acids containing one or more amino substituents. GO:0006576 cellular biogenic amine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006576 biogenic amine metabolism The chemical reactions and pathways occurring at the level of individual cells involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters. GO:0006573 valine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006573 valine metabolism The chemical reactions and pathways involving valine, 2-amino-3-methylbutanoic acid. GO:0006574 valine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006574 MetaCyc:VALDEG-PWY valine catabolism|valine degradation|valine breakdown The chemical reactions and pathways resulting in the breakdown of valine, 2-amino-3-methylbutanoic acid. GO:0006571 tyrosine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006571 MetaCyc:PWY-3461 tyrosine anabolism|tyrosine synthesis|tyrosine formation|tyrosine biosynthesis The chemical reactions and pathways resulting in the formation of tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid. GO:0006572 tyrosine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006572 tyrosine degradation|tyrosine breakdown|tyrosine catabolism The chemical reactions and pathways resulting in the breakdown of tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid. GO:0031519 PcG protein complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0031519 Polycomb Group protein complex A chromatin-associated multiprotein complex containing Polycomb Group proteins. In Drosophila, Polycomb group proteins are involved in the long-term maintenance of gene repression, and PcG protein complexes associate with Polycomb group response elements (PREs) in target genes to regulate higher-order chromatin structure. GO:0006570 tyrosine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006570 Wikipedia:Tyrosine|UM-BBD_pathwayID:tyr tyrosine metabolism The chemical reactions and pathways involving tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid. CHEBI:136235 phosphatidylinositol 36:4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136235 CHEBI:136236 phosphatidylinositol 36:2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136236 CHEBI:136239 phosphatidylinositol 38:4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136239 GO:0031510 SUMO activating enzyme complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031510 SAE|SUMO E1 activator enzyme complex A conserved heterodimeric complex with SUMO activating enzyme activity. NCBITaxon:43738 Schizophora organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_43738 CHEBI:32829 D-threonyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32829 PR:000007892 glucagon receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000007892 GL-R|GCGR A glucagon-like receptor that is a translation product of the human GCGR gene or a 1:1 ortholog thereof. CHEBI:32822 L-threoninium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32822 PR:000007893 GTP cyclohydrolase 1 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000007893 DYT5|GCH|GCH1|GTP cyclohydrolase I|GTP-CH-I A protein that is a translation product of the human GCH1 gene or a 1:1 ortholog thereof. CHEBI:32823 L-threonyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32823 NCBITaxon:43733 Muscomorpha organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_43733 Asilomorpha CHEBI:32826 D-allothreonine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32826 CHEBI:32827 D-threoninate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32827 CHEBI:32828 D-threoninium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32828 CHEBI:32820 L-threoninate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32820 CHEBI:91126 2-trans,4-trans-xanthoxin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91126 CHEBI:91128 3-acetylchlorophyllide a biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_91128 CHEBI:91121 beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91121 CHEBI:32832 threoninate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32832 CHEBI:32833 threoninium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32833 CHEBI:32835 threonine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32835 CHEBI:32836 L-serinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32836 CHEBI:32837 L-serinium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32837 CHEBI:91118 N-acetyl-alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91118 CHEBI:91119 alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91119 CHEBI:32807 o-orsellinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32807 CHEBI:32808 (Z)-5-oxohex-2-enedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32808 CHEBI:91140 15(R)-HEPE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_91140 CHEBI:32809 3-hydroxy-L-glutamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32809 CHEBI:32800 (S)-mandelic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32800 CHEBI:32802 (S)-4-hydroxymandelic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32802 CHEBI:32803 (R)-4-hydroxymandelic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32803 CHEBI:32804 4-hydroxymandelate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32804 CHEBI:32805 cis-aconitic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32805 CHEBI:32806 trans-aconitic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32806 CHEBI:17209 dihydrosanguinarine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17209 CHEBI:17206 9,11alpha-epoxypregn-4-ene-3,20-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17206 CHEBI:17207 2-methylideneglutaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17207 CHEBI:17204 4,5-dioxopentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17204 OIO:hasOBONamespace has_obo_namespace biolink:OntologyClass go-plus http://www.geneontology.org/formats/oboInOwl#hasOBONamespace CHEBI:17202 IMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17202 CHEBI:17203 L-proline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17203 CHEBI:17200 UDP-alpha-D-glucuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17200 CHEBI:17201 glycylglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17201 CHEBI:91143 (3S,5R,6S)-beta-cryptoxanthin 5,6-epoxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91143 CHEBI:32818 p-coumaroylagmatine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32818 CHEBI:32819 L-2-amino-4-chloropent-4-enoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32819 CHEBI:91130 2-trans-(+)-abscisic aldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91130 UBERON:0017261 intertarsal sesamoid biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0017261 tarsal sesamoid A sesamoid element that is part of a tarsal skeleton. CHEBI:32810 3-hydroxy-L-glutamate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32810 CHEBI:32811 4-hydroxy-L-glutamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32811 CHEBI:32812 4-hydroxy-L-glutamate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32812 CHEBI:32813 N-amidino-L-aspartate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32813 CHEBI:32814 N-carbamoyl-L-aspartate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32814 CHEBI:32815 enol-phenylpyruvic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32815 CHEBI:32816 pyruvic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32816 CHEBI:32817 keto-3-deoxy-D-manno-octulosonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32817 CHEBI:91136 5(S),11(R)-DiHETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_91136 CHEBI:91137 17(R)-HDoHE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_91137 CHEBI:91138 5(S),15(R)-DiHETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_91138 CHEBI:91139 elastin-laminin receptor agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_91139 CHEBI:91132 18(R)-HETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_91132 CHEBI:91133 prostaglandin H1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_91133 CHEBI:91134 L-erythrulose 4-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_91134 CHEBI:91135 19-hydroxyprostaglandin H1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_91135 CHEBI:91165 capsanthin 5,6-epoxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91165 CHEBI:91180 (R)-3-(indol-3-yl)-2-oxobutyrate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91180 CHEBI:91181 2-phosphinomethylmalate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91181 CHEBI:91175 hypusine(2+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91175 NCBITaxon:43746 Ephydroidea organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_43746 GO:0031599 obsolete ER proteasome regulatory particle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031599 OBSOLETE. The regulatory subcomplex of a proteasome located in the endoplasmic reticulum of a cell. NCBITaxon:43741 Acalyptratae organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_43741 UBERON:4100000 skeletal element projection biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_4100000 Anatomical projection that is composed of bone or cartilage tissue. GO:0031590 wybutosine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031590 wybutosine metabolism|yW metabolism|yW metabolic process The chemical reactions and pathways involving wybutosine, 3H-imidazo[1,2-alpha]purine-7-butanoic acid, 4,9-dihydro- alpha-[(methoxycarbonyl)amino]- 4,6-dimethyl-9-oxo- 3-beta-D-ribofuranosyl methyl ester, a modified nucleoside found in some tRNA molecules. GO:0031597 cytosolic proteasome complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031597 A proteasome complex found in the cytosol of a cell. GO:0031598 nuclear proteasome regulatory particle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031598 The regulatory subcomplex of a proteasome located in the nucleus of a cell. GO:0031595 nuclear proteasome complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031595 A proteasome found in the nucleus of a cell. GO:0031596 obsolete ER proteasome complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031596 OBSOLETE. A proteasome found in the endoplasmic reticulum of a cell. GO:0031593 polyubiquitin modification-dependent protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031593 Interacting selectively and non-covalently with a protein upon poly-ubiquitination of the target protein. CHEBI:91176 deoxyhypusine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_91176 GO:0031594 neuromuscular junction biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031594 Wikipedia:Neuromuscular_junction|NIF_Subcellular:sao1124888485 motor endplate|NMJ The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential. CHEBI:91177 maltose 6'-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91177 CHEBI:91178 N-demethylindolmycin(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91178 GO:0031591 wybutosine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031591 yW biosynthesis|yW biosynthetic process The chemical reactions and pathways resulting in the formation of wybutosine, 3H-imidazo[1,2-alpha]purine-7-butanoic acid, 4,9-dihydro- alpha-[(methoxycarbonyl)amino]- 4,6-dimethyl-9-oxo- 3-beta-D-ribofuranosyl methyl ester, a modified nucleoside found in some tRNA molecules. CHEBI:91179 indolmycin(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91179 GO:0031592 centrosomal corona biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031592 An amorphous structure surrounding the core of the centrosome, from which microtubules are nucleated; contains gamma-tubulin. CHEBI:17150 2-phosphoglycolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17150 CHEBI:17151 xylitol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17151 CHEBI:42115 3-deoxy-alpha-D-manno-2-octulosonic acid 8-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_42115 CHEBI:32789 tyrosine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32789 CHEBI:42112 1-(2-deoxy-5-O-phosphono-beta-L-ribofuranosyl)thymine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_42112 CHEBI:42111 (R)-lactic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_42111 CHEBI:32784 tyrosinate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32784 CHEBI:32785 tyrosinate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32785 CHEBI:32786 tyrosinium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32786 CHEBI:17149 N-acetyl-beta-D-glycosaminyl glycopeptide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17149 CHEBI:17147 5-amino-4-chloro-2-(2,3-dihydroxyphenyl)pyridazin-3(2H)-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17147 CHEBI:17148 putrescine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17148 CHEBI:17146 anhydrotetracycline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17146 CHEBI:17143 5,6-dihydroxy-3-methyl-5,6-dihydroquinolin-2(1H)-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17143 CHEBI:17144 2-(3-amino-3-carboxypropyl)-L-histidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17144 PR:000007806 galanin biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000007806 GAL1|GALN|GAL|GLNN A protein that is a translation product of the human GAL gene or a 1:1 ortholog thereof. CHEBI:17141 cysteamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17141 CHEBI:17142 5-formyl-2-hydroxyhepta-2,4-dienedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17142 CHEBI:17140 D-xylulose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17140 CHEBI:42101 D-norleucine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_42101 CHEBI:32796 (R)-2-hydroxyglutaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32796 CHEBI:17138 glyceraldehyde 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17138 CHEBI:32797 (S)-2-hydroxyglutaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32797 CHEBI:17139 6-O-sulfo-alpha-D-Glc-(1->6)-alpha-D-Glc-(1->6)-alpha-D-Glc-(1->3)-1-O-alkyl-2-O-acylglycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17139 CHEBI:32798 9-cis,11-trans-octadecadienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32798 CHEBI:17136 2,8-dihydroxy-1,4-naphthoquinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17136 CHEBI:17137 hydrogensulfite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17137 CHEBI:17134 octopamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17134 CHEBI:17135 long-chain fatty alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17135 CHEBI:17132 diethyl (2R,3R)-2-hydroxy-3-methylsuccinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17132 CHEBI:17133 deoxylimonoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17133 CHEBI:17130 10-oxocapric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17130 CHEBI:17131 (3,5-diiodo-4-hydroxyphenyl)pyruvic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17131 CHEBI:17172 2'-deoxyguanosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17172 CHEBI:17173 D-ribulose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17173 CHEBI:17170 dimethylamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17170 UBERON:0007997 sesamoid bone of manus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007997 sesamoid bone of hand A sesamoid bone that is part of a manus. CHEBI:32760 L-tyrosinate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32760 CHEBI:32761 L-tyrosinate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32761 CHEBI:32762 L-tyrosinium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32762 CHEBI:32764 L-tyrosyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32764 CHEBI:17169 benzaldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17169 CHEBI:17167 (R)-lactaldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17167 CHEBI:17168 5alpha-cholest-7-en-3beta-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17168 CHEBI:17165 Photinus luciferin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17165 CHEBI:17166 N-methylputrescine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17166 CHEBI:17163 S-methyl D-thioglycerate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17163 CHEBI:17164 stachyose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17164 CHEBI:17161 O-demethylpuromycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17161 CHEBI:17162 2-oxooctadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17162 CHEBI:17160 17alpha-estradiol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17160 CHEBI:32778 D-tyrosyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32778 CHEBI:32773 D-tyrosinate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32773 CHEBI:32774 D-tyrosinate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32774 CHEBI:32775 D-tyrosinium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32775 CHEBI:17158 methylglyoxal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17158 CHEBI:17159 (R)-carnitinamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17159 CHEBI:17156 1D-3-amino-1-guanidino-1,3-dideoxy-scyllo-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17156 CHEBI:17157 trans,trans-2,3,4,5-tetradehydroacyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17157 CHEBI:17154 nicotinamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17154 CHEBI:17155 flavonol 3-O-(6-O-malonyl-beta-D-glucoside) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17155 CHEBI:17152 phosphatidyl-N,N-dimethylethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17152 CHEBI:17153 propanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17153 CHEBI:32744 L-selenocysteinium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32744 CHEBI:32747 D-selenocysteinate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32747 CHEBI:17109 7,8-dihydro-7,8-dihydroxykynurenic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17109 CHEBI:17108 D-arabinose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17108 CHEBI:17105 4-maleylacetoacetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17105 CHEBI:32742 L-selenocysteinate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32742 CHEBI:32743 L-selenocysteinate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32743 CHEBI:17106 1-alkyl-sn-glycerol 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17106 CHEBI:17103 N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide(d18:1(4E)) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17103 CHEBI:17104 6-hydroxyprotopine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17104 CHEBI:17101 macarpine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17101 CHEBI:17102 phosphoramide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17102 CHEBI:17100 L-arabinono-1,4-lactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17100 CHEBI:175901 gemcitabine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_175901 PR:000007856 gastrin biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000007856 GAST|GAS A protein that is a translation product of the human GAST gene or a 1:1 ortholog thereof. CHEBI:32750 D-selenocysteinate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32750 CHEBI:32751 D-selenocysteinium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32751 CHEBI:32752 selenocysteinate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32752 CHEBI:32753 selenocysteinate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32753 CHEBI:32754 selenocysteinium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32754 CHEBI:32722 glycyl radical residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32722 CHEBI:32727 tryptophanate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32727 CHEBI:32728 tryptophanium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32728 CHEBI:17129 (S)-scoulerine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17129 CHEBI:17127 glucotropeolin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17127 CHEBI:17128 adipate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17128 CHEBI:32721 glycyl radical biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32721 CHEBI:17125 6-acetamido-3-aminohexanoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17125 CHEBI:17126 carnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17126 CHEBI:17123 2-aminoacrylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17123 CHEBI:17121 oxomalonate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17121 CHEBI:17122 aldehydo-N-acetyl-D-mannosamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17122 CHEBI:17120 hexanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17120 CHEBI:17118 aldehydo-D-galactose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17118 CHEBI:17119 fMet-tRNA(fMet) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17119 CHEBI:17117 5-dehydro-4-deoxy-D-glucuronate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17117 CHEBI:17114 N(5)-formyl-5,6,7,8-tetrahydromethanopterin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17114 CHEBI:17115 L-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17115 CHEBI:17113 erythritol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17113 CHEBI:17110 1-guanidino-1-deoxy-scyllo-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17110 CHEBI:17111 5-O-phosphono-alpha-D-ribofuranosyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17111 GO:0031506 cell wall glycoprotein biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031506 cell wall glycoprotein anabolism|cell wall glycoprotein biosynthesis|cell wall glycoprotein synthesis|cell wall glycoprotein formation The chemical reactions and pathways resulting in the formation of cell wall glycoproteins, any cell wall protein that contains covalently bound sugar residues. GO:0031507 heterochromatin assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031507 establishment of heterochromatin architecture involved in chromatin silencing at pericentric region|establishment of heterochromatin architecture|heterochromatin formation involved in chromatin silencing at centromere outer repeat region|heterochromatin assembly involved in chromatin silencing at pericentric region|heterochromatin formation|heterochromatin assembly involved in chromatin silencing|heterochromatin formation involved in chromatin silencing at pericentric region|establishment of heterochromatic silencing|heterochromatin formation involved in chromatin silencing|heterochromatin assembly involved in chromatin silencing at centromere outer repeat region|establishment of heterochromatin architecture involved in chromatin silencing at centromere outer repeat region|establishment of chromatin silencing The assembly of chromatin into heterochromatin, a compact and highly condensed form that is often, but not always, transcriptionally silent. GO:0006548 histidine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006548 histidine catabolism|histidine degradation|histidine breakdown The chemical reactions and pathways resulting in the breakdown of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid. GO:0031504 peptidoglycan-based cell wall organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031504 peptidoglycan-based cell wall organization and biogenesis|peptidoglycan-based cell wall organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the peptidoglycan-based cell wall. GO:0006549 isoleucine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006549 isoleucine metabolism The chemical reactions and pathways involving isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid. GO:0031505 fungal-type cell wall organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031505 beta-glucan-containing cell wall organization and biogenesis|chitin- and beta-glucan-containing cell wall organization and biogenesis|fungal-type cell wall organization and biogenesis|chitin- and beta-glucan-containing cell wall organisation|chitin-containing cell wall organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fungal-type cell wall. GO:0031502 dolichyl-phosphate-mannose-protein mannosyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031502 PMT family mannosyltransferase complex|protein O-mannosyltransferase complex A complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity; usually includes members of the PMT1 and PMT2 protein subfamilies. GO:0006546 glycine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006546 glycine catabolism|glycine degradation|glycine breakdown The chemical reactions and pathways resulting in the breakdown of glycine, aminoethanoic acid. CHEBI:42191 ethylenediaminetetraacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_42191 GO:0031503 protein-containing complex localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031503 establishment and maintenance of protein complex localization|protein complex localisation|protein complex localization A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location. GO:0006547 histidine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006547 Wikipedia:Histidine histidine metabolism The chemical reactions and pathways involving histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid. GO:0031500 Tea1 cell-end complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031500 A high molecular weight complex characterized in S. pombe containing the cell-end anchoring protein Tea1. This complex is transported to the cell ends by microtubules and is involved in bipolar growth and the maintennce of normal cell polarity. GO:0006544 glycine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006544 glycine metabolism The chemical reactions and pathways involving glycine, aminoethanoic acid. GO:0006545 glycine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006545 MetaCyc:GLYCINE-SYN2-PWY glycine anabolism|glycine synthesis|glycine formation|glycine biosynthesis The chemical reactions and pathways resulting in the formation of glycine, aminoethanoic acid. GO:0031501 mannosyltransferase complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0031501 A complex that posseses mannosyltransferase activity. GO:0006542 glutamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006542 MetaCyc:GLNSYN-PWY glutamine anabolism|glutamine synthesis|glutamine formation|glutamine biosynthesis The chemical reactions and pathways resulting in the formation of glutamine, 2-amino-4-carbamoylbutanoic acid. GO:0006543 glutamine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006543 glutamine catabolism|glutamine degradation|glutamine breakdown The chemical reactions and pathways resulting in the breakdown of glutamine, 2-amino-4-carbamoylbutanoic acid. GO:0006540 glutamate decarboxylation to succinate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006540 MetaCyc:GLUDEG-I-PWY|MetaCyc:PWY3O-210|MetaCyc:PWY-4321 glutamate degradation via GABA|degradation of glutamate to succinate through GABA|4-aminobutyrate shunt|GABA shunt|glutamate degradation via 4-aminobutyrate|gamma-aminobutyrate shunt The chemical reactions and pathways resulting in the formation of succinate from glutamate. Also known as GABA (gamma-aminobutyrate) shunt since it channels glutamate into the TCA cycle bypassing two steps of that cycle. There are three enzymes involved in the GABA shunt: glutamate decarboxylase (GAD), GABA aminotransferase (GABA-TA), and succinate semialdehyde dehydrogenase (SSADH). These three enzymes acting in concert to convert glutamate into succinate. The GABA shunt is predominantly associated with neurotransmission in the mammalian brain. It is also present in nonneuronal cells, in plants, in unicellular eukaryotes, and in prokaryotes. GO:0006541 glutamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006541 glutamine metabolism The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid. GO:0031508 pericentric heterochromatin assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031508 centromeric heterochromatin formation|chromatin silencing at centromere outer repeat region|centromere chromatin silencing|centric heterochromatin formation|heterochromatic silencing at centromere|centromeric heterochromatin biosynthesis|chromatin silencing at pericentric region|centromeric silencing|chromatin silencing at centromere The assembly of chromatin located adjacent to the CENP-A rich centromere 'central core' and characterized by the modified histone H3K9me3, into heterochromatin, resulting in the repression of transcription of centromeric DNA. GO:0031509 subtelomeric heterochromatin assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031509 subtelomeric silencing|subtelomere chromatin silencing|chromatin silencing at subtelomere|telomeric heterochromatin assembly|establishment of chromatin silencing at telomere|telomeric heterochromatin formation|heterochromatic silencing at subtelomere The assembly of chromatin into heterochromatin at the subtelomeric region. GO:0006559 L-phenylalanine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006559 L-phenylalanine catabolism|L-phenylalanine degradation|L-phenylalanine breakdown|phenylalanine catabolism|phenylalanine catabolic process The chemical reactions and pathways resulting in the breakdown of phenylalanine, 2-amino-3-phenylpropanoic acid. GO:0006557 S-adenosylmethioninamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006557 S-adenosylmethioninamine biosynthesis|S-adenosylmethioninamine anabolism|S-adenosylmethioninamine synthesis|S-adenosylmethioninamine formation The chemical reactions and pathways resulting in the formation of S-adenosylmethioninamine, (5-deoxy-5-adenosyl)(3-aminopropyl) methylsulfonium salt. GO:0006558 L-phenylalanine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006558 L-phenylalanine metabolism|phenylalanine metabolic process|phenylalanine metabolism The chemical reactions and pathways involving L-phenylalanine, the L-enantiomer of 2-amino-3-phenylpropanoic acid, i.e. (2S)-2-amino-3-phenylpropanoic acid. GO:0006555 methionine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006555 UM-BBD_pathwayID:met methionine and threonine metabolic process|methionine and threonine metabolism|methionine metabolism The chemical reactions and pathways involving methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins. GO:0006556 S-adenosylmethionine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006556 MetaCyc:SAM-PWY S-adenosylmethionine anabolism|S-adenosylmethionine synthesis|S-adenosylmethionine formation|SAM biosynthetic process|S-adenosylmethionine biosynthesis|S-adenosyl methionine biosynthetic process|S-adenosyl methionine biosynthesis The chemical reactions and pathways resulting in the formation of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism. GO:0006553 lysine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006553 Wikipedia:Lysine lysine metabolism The chemical reactions and pathways involving lysine, 2,6-diaminohexanoic acid. GO:0006554 lysine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006554 lysine breakdown|lysine catabolism|lysine degradation The chemical reactions and pathways resulting in the breakdown of lysine, 2,6-diaminohexanoic acid. GO:0006551 leucine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006551 leucine metabolism The chemical reactions and pathways involving leucine, 2-amino-4-methylpentanoic acid. GO:0006552 leucine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006552 MetaCyc:LEU-DEG2-PWY leucine breakdown|leucine catabolism|leucine degradation The chemical reactions and pathways resulting in the breakdown of leucine, 2-amino-4-methylpentanoic acid. GO:0006550 isoleucine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006550 MetaCyc:ILEUDEG-PWY isoleucine degradation|isoleucine breakdown|isoleucine catabolism The chemical reactions and pathways resulting in the breakdown of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid. CHEBI:136335 13-(octadecanoyloxy)octadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136335 CHEBI:136330 12-(octadecanoyloxy)octadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136330 GO:0006528 asparagine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006528 MetaCyc:ASPARAGINESYN-PWY asparagine metabolism The chemical reactions and pathways involving asparagine, 2-amino-3-carbamoylpropanoic acid. BSPO:0001101 in_deep_part_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BSPO_0001101 BSPO:0001101 X superficial_part_of Y <=> if Y is subdivided into two superficial and deep portions, X is part_of the deep portion. GO:0006529 asparagine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006529 asparagine anabolism|asparagine biosynthesis|asparagine synthesis|asparagine formation The chemical reactions and pathways resulting in the formation of asparagine, 2-amino-3-carbamoylpropanoic acid. GO:0006526 arginine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006526 MetaCyc:ARGSYN-PWY|MetaCyc:ARGSYNBSUB-PWY|MetaCyc:ARGININE-SYN4-PWY arginine biosynthesis|arginine anabolism|arginine synthesis|arginine formation The chemical reactions and pathways resulting in the formation of arginine, 2-amino-5-(carbamimidamido)pentanoic acid. GO:0006527 arginine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006527 arginine degradation|arginine catabolism|arginine breakdown The chemical reactions and pathways resulting in the breakdown of arginine, 2-amino-5-(carbamimidamido)pentanoic acid. BSPO:0001100 in_superficial_part_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BSPO_0001100 BSPO:0001100 X superficial_part_of Y <=> if Y is subdivided into two superficial and deep portions, X is part_of the superficial portion. GO:0006524 alanine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006524 alanine degradation|alanine breakdown|alanine catabolism The chemical reactions and pathways resulting in the breakdown of alanine, 2-aminopropanoic acid. BSPO:0001106 proximalmost_part_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BSPO_0001106 BSPO:0001106 X proximalmost_part_of Y <=> X is part_of Y and X is adjacent_to the proximal boundary of Y GO:0006525 arginine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006525 Wikipedia:Arginine arginine metabolism The chemical reactions and pathways involving arginine, 2-amino-5-(carbamimidamido)pentanoic acid. GO:0006522 alanine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006522 alanine metabolism The chemical reactions and pathways involving alanine, 2-aminopropanoic acid. GO:0006523 alanine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006523 alanine biosynthesis|alanine anabolism|alanine synthesis|alanine formation The chemical reactions and pathways resulting in the formation of alanine, 2-aminopropanoic acid. GO:0006520 cellular amino acid metabolic process biolink:BiologicalProcess go-plus goslim_yeast|goslim_pir|goslim_drosophila|goslim_aspergillus|goslim_generic|goslim_pombe|goslim_chembl http://purl.obolibrary.org/obo/GO_0006520 amino acid metabolic process|cellular amino acid and derivative metabolic process|amino acid and derivative metabolism|cellular amino acid metabolism The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells. GO:0006521 regulation of cellular amino acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006521 regulation of amino acid metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids. BSPO:0001107 immediately_deep_to biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BSPO_0001107 BSPO:0001107 This relation holds when both the deep_to and ajdacent_to relationship similarly hold. CHEBI:136309 9-[(9Z)-hexadecenoyloxy]octadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136309 BSPO:0001108 distalmost_part_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BSPO_0001108 BSPO:0001108 X distalmost_part_of Y <=> X is part_of Y and X is adjacent_to the distal boundary of Y CHEBI:136303 13-[(9Z)-octadecenoyloxy]octadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136303 CHEBI:136304 13-hydroxyoctadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136304 CHEBI:136302 12-[(9Z)-octadecenoyloxy]octadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136302 UBERON:0007914 bone of craniocervical region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007914 head or neck bone|cranial bone A bone that is part of a craniocervical region. GO:0006539 glutamate catabolic process via 2-oxoglutarate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006539 MetaCyc:P162-PWY glutamate breakdown via 2-oxoglutarate|glutamate degradation via 2-oxoglutarate|glutamate catabolic process via 2-ketoglutarate|glutamate catabolic process via alpha-oxoglutarate|glutamate catabolism via alpha-ketoglutarate|glutamate catabolism via alpha-oxoglutarate|glutamate catabolism via 2-ketoglutarate|glutamate catabolic process via alpha-ketoglutarate The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-oxoglutarate. BSPO:0001113 preaxialmost_part_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BSPO_0001113 BSPO:0001113 GO:0006537 glutamate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006537 glutamate biosynthesis, using glutamate synthase (NADPH)|glutamate biosynthetic process, using glutamate synthase (NADPH)|glutamate anabolism|glutamic acid biosynthetic process|glutamic acid biosynthesis|glutamate biosynthesis, using glutamate dehydrogenase (NAD(P)+)|glutamate synthesis|glutamate biosynthetic process, using glutamate dehydrogenase (NAD(P)+)|glutamate formation|glutamate biosynthesis The chemical reactions and pathways resulting in the formation of glutamate, the anion of 2-aminopentanedioic acid. GO:0006538 glutamate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006538 glutamic acid catabolism|glutamic acid catabolic process|glutamate catabolism|glutamate deamidation|glutamate degradation|glutamate breakdown The chemical reactions and pathways resulting in the breakdown of glutamate, the anion of 2-aminopentanedioic acid. GO:0006535 cysteine biosynthetic process from serine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006535 MetaCyc:CYSTSYN-PWY cysteine anabolism from serine|cysteine synthesis from serine|cysteine formation from serine The chemical reactions and pathways resulting in the formation of cysteine from other compounds, including serine. GO:0006536 glutamate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006536 Wikipedia:Glutamic_acid glutamic acid metabolism|glutamic acid metabolic process|glutamate metabolism The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid. GO:0006533 aspartate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006533 aspartate degradation|aspartate breakdown|aspartate catabolism The chemical reactions and pathways resulting in the breakdown of aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid. BSPO:0001115 postaxialmost_part_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BSPO_0001115 BSPO:0001115 GO:0006534 cysteine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006534 Wikipedia:Cysteine_metabolism cysteine metabolism The chemical reactions and pathways involving cysteine, 2-amino-3-mercaptopropanoic acid. GO:0006531 aspartate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006531 aspartate metabolism The chemical reactions and pathways involving aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid. GO:0006532 aspartate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006532 aspartate biosynthesis|aspartate formation|aspartate anabolism|aspartate synthesis The chemical reactions and pathways resulting in the formation of aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid. GO:0006530 asparagine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006530 asparagine degradation|asparagine breakdown|asparagine catabolism The chemical reactions and pathways resulting in the breakdown of asparagine, 2-amino-3-carbamoylpropanoic acid. CHEBI:42164 3-ammonio-L-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_42164 CHEBI:136315 13-[(9Z)-hexadecenoyloxy]octadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136315 CHEBI:136312 12-[(9Z)-hexadecenoyloxy]octadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136312 GO:0006506 GPI anchor biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006506 GPI anchor anabolism|GPI anchor synthesis|GPI anchor formation|glycosylphosphatidylinositol biosynthetic process|glycosylphosphatidylinositol biosynthesis|GPI/GSI anchor biosynthetic process|GPI/GSI anchor biosynthesis|GPI anchor biosynthesis The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol group is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage. CHEBI:17194 bromochloromethane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17194 GO:0006507 GPI anchor release biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006507 The GPI anchor metabolic process that results in enzymatic cleavage of the anchor, releasing an anchored protein from the membrane. CHEBI:17195 thiomorpholine-3-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17195 GO:0006504 obsolete C-terminal protein geranylgeranylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006504 C-terminal protein geranylgeranylation OBSOLETE. The covalent or non-covalent attachment of a geranylgeranyl group to the carboxy-terminus of a protein. CHEBI:17192 3,5-dibromo-4-hydroxybenzonitrile biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17192 GO:0006505 GPI anchor metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006505 GPI anchor metabolism|glycosylphosphatidylinositol metabolic process|GPI/GSI anchor metabolic process|glycosylphosphatidylinositol metabolism|GPI/GSI anchor metabolism The chemical reactions and pathways involving glycosylphosphatidylinositol anchors, molecular mechanisms for attaching membrane proteins to the lipid bilayer of cell membranes. Structurally they consist of a molecule of phosphatidylinositol to which is linked, via the C-6 hydroxyl of the inositol, a carbohydrate chain. This chain is in turn linked to the protein through an ethanolamine phosphate group, the amino group of which is in amide linkage with the C-terminal carboxyl of the protein chain, the phosphate group being esterified to the C-6 hydroxyl of the terminal mannose of the core carbohydrate chain. CHEBI:17193 ADP-aldose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17193 GO:0006502 obsolete C-terminal protein prenylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006502 C-terminal protein prenylation OBSOLETE. The covalent or non-covalent attachment of a prenyl group to the carboxy-terminus of a protein; geranyl, farnesyl, or geranylgeranyl groups may be added. GO:0006503 obsolete C-terminal protein farnesylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006503 C-terminal protein farnesylation OBSOLETE. The covalent or non-covalent attachment of a farnesyl group to the carboxy terminus of a protein. CHEBI:17191 L-isoleucine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17191 GO:0006500 N-terminal protein palmitoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006500 The covalent attachment of a palmitoyl group to the N-terminal amino acid residue of a protein. GO:0006501 C-terminal protein lipidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006501 The covalent attachment of a lipid group to the carboxy-terminus of a protein. CHEBI:42156 17-epiestriol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_42156 CHEBI:17189 2,5-dihydroxybenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17189 CHEBI:17187 pinene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17187 CHEBI:17188 nucleoside 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17188 CHEBI:4553 dihydroanhydropodorhizol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_4553 GO:0006508 proteolysis biolink:BiologicalProcess go-plus goslim_chembl|goslim_pir|goslim_metagenomics http://purl.obolibrary.org/obo/GO_0006508 Wikipedia:Proteolysis peptidolysis|ATP-dependent proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. CHEBI:17185 2,3,5-trihydroxytoluene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17185 GO:0006509 membrane protein ectodomain proteolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006509 receptor shedding|membrane protein solubilization|ectodomain cleavage|ectoderm shedding The proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain). CHEBI:17183 sanguinarine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17183 GO:0006517 protein deglycosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006517 glycoprotein deglycosylation The removal of sugar residues from a glycosylated protein. GO:0006518 peptide metabolic process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0006518 peptide metabolism The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. CHEBI:17184 chlordecone alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17184 GO:0006515 protein quality control for misfolded or incompletely synthesized proteins biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006515 misfolded or incompletely synthesized protein degradation|misfolded or incompletely synthesized protein breakdown|protein quality control by the ubiquitin-proteasome system|misfolded or incompletely synthesized protein catabolic process|misfolded or incompletely synthesized protein catabolism|protein quality control (PQC)|degradation of misfolded or incompletely synthesized proteins The chemical reactions and pathways resulting in the breakdown of misfolded or attenuated proteins. CHEBI:17181 5-(4-acetoxybut-1-ynyl)-2,2'-bithiophene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17181 GO:0006516 glycoprotein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006516 glycoprotein breakdown|glycoprotein catabolism|glycoprotein degradation The chemical reactions and pathways resulting in the breakdown of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. GO:0006513 protein monoubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006513 protein monoubiquitylation|protein monoubiquitinylation Addition of a single ubiquitin group to a protein. GO:0006514 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006514 CHEBI:17180 3-hydroxypyruvate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17180 GO:0006511 ubiquitin-dependent protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006511 protein ubiquitylation during ubiquitin-dependent protein catabolism|ubiquitin-dependent proteolysis|protein ubiquitinylation during ubiquitin-dependent protein catabolism|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|protein ubiquitinylation during ubiquitin-dependent protein catabolic process|protein ubiquitylation during ubiquitin-dependent protein catabolic process|myofibrillar protein ubiquitination during ubiquitin-dependent protein degradation|protein ubiquitination during ubiquitin-dependent protein catabolism|protein ubiquitination during ubiquitin-dependent protein degradation|myofibrillar protein ubiquitination during ubiquitin-dependent protein breakdown|myofibrillar protein ubiquitination during ubiquitin-dependent protein catabolism|ubiquitin-dependent protein degradation|protein ubiquitination during ubiquitin-dependent protein breakdown|ubiquitin-dependent protein catabolism|myofibrillar protein ubiquitination during ubiquitin-dependent protein catabolic process|protein ubiquitination during ubiquitin-dependent protein catabolic process|ubiquitin-dependent protein breakdown|protein degradation tagging activity The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein. GO:0006512 obsolete ubiquitin cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006512 ubiquitin cycle OBSOLETE. The cyclical process by which one or more ubiquitin groups are added to (ubiquitination) and removed from (deubiquitination) a protein. CHEBI:42147 (4R,5R)-1,2-dithiane-4,5-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_42147 GO:0006510 obsolete ATP-dependent proteolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006510 ATP-dependent proteolysis|ATP-dependent peptidolysis OBSOLETE. The hydrolysis of a peptide bond or bonds within a protein using energy from the hydrolysis of ATP. OBA:VT0002706 kidney size trait biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_VT0002706 size of kidney The size of a kidney. CHEBI:17179 taurolithocholate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17179 CHEBI:17176 long-chain fatty aldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17176 CHEBI:17177 cinnamyl alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17177 GO:0006519 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006519 CHEBI:17174 heparosan N-sulfate L-iduronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17174 CHEBI:17175 guanidinoethyl methyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17175 CHEBI:17198 dolichyl N-acetyl-alpha-D-glucosaminyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17198 CHEBI:17199 4,5-dihydroxyphthalic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17199 CHEBI:17196 L-asparagine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17196 CHEBI:17197 1-alkylglycerone 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17197 GO:0016070 RNA metabolic process biolink:BiologicalProcess go-plus goslim_agr|goslim_candida|goslim_pir|goslim_aspergillus|goslim_metagenomics http://purl.obolibrary.org/obo/GO_0016070 RNA metabolism The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. GO:0016071 mRNA metabolic process biolink:BiologicalProcess go-plus goslim_drosophila|goslim_pombe http://purl.obolibrary.org/obo/GO_0016071 mRNA metabolism The chemical reactions and pathways involving mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes. GO:0016072 rRNA metabolic process biolink:BiologicalProcess go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0016072 rRNA metabolism The chemical reactions and pathways involving rRNA, ribosomal RNA, a structural constituent of ribosomes. GO:0065001 specification of axis polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0065001 The pattern specification process in which the polarity of a body or organ axis is established and maintained. GO:0065004 protein-DNA complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0065004 DNA-protein complex assembly The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex. GO:0065005 protein-lipid complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0065005 The aggregation, arrangement and bonding together of proteins and lipids to form a protein-lipid complex. GO:0065002 intracellular protein transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0065002 intracellular protein transport across a membrane|intracellular membrane translocation of a protein|intracellular protein membrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore. GO:0065003 protein-containing complex assembly biolink:BiologicalProcess go-plus goslim_pir|goslim_metagenomics|goslim_generic|goslim_pombe|goslim_chembl http://purl.obolibrary.org/obo/GO_0065003 macromolecular complex assembly|chaperone activity|protein complex formation|macromolecule complex assembly|protein complex assembly The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex. GO:0065008 regulation of biological quality biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0065008 regulation of biological attribute|regulation of biological characteristic Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc. GO:0065009 regulation of molecular function biolink:BiologicalProcess go-plus gocheck_do_not_annotate|goslim_pir|goslim_plant http://purl.obolibrary.org/obo/GO_0065009 regulation of a molecular function Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. GO:0065006 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0065006 GO:0065007 biological regulation biolink:BiologicalProcess go-plus gocheck_do_not_annotate|goslim_pir http://purl.obolibrary.org/obo/GO_0065007 regulation Any process that modulates a measurable attribute of any biological process, quality or function. GO:0016066 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016066 GO:0016067 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016067 GO:0016068 type I hypersensitivity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016068 Wikipedia:Type_I_hypersensitivity immediate hypersensitivity response An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors on mast cells or basophils, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines. GO:0016069 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016069 GO:0016062 adaptation of rhodopsin mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016062 adaptation of rhodopsin mediated signalling The process in which a rhodopsin-mediated signaling pathway is adjusted to modulate the sensitivity and response of a visual system to light stimuli (that might vary over more than 6 magnitudes in intensity) without response saturation. GO:0016063 rhodopsin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016063 rhodopsin biosynthesis|rhodopsin synthesis|rhodopsin formation|rhodopsin anabolism The chemical reactions and pathways resulting in the formation of rhodopsin, a brilliant purplish-red, light-sensitive visual pigment found in the rod cells of the retinas. CHEBI:91089 CMP-8-amino-3,8-dideoxy-alpha-D-manno-oct-2-ulosonate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91089 GO:0016064 immunoglobulin mediated immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016064 antibody-mediated immune response An immune response mediated by immunoglobulins, whether cell-bound or in solution. GO:0016065 obsolete humoral defense mechanism (sensu Protostomia) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016065 humoral defense mechanism (sensu Protostomia)|humoral defence mechanism (sensu Protostomia) OBSOLETE. The specific immune response mediated by antibodies. As in, but not restricted to, the taxon Protostomia (Protostomia, ncbi_taxonomy_id:33317). GO:0016080 synaptic vesicle targeting biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016080 The process in which synaptic vesicles are directed to specific destination membranes, mediated by molecules at the vesicle membrane and target membrane surfaces. GO:0016081 synaptic vesicle docking biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0016081 synaptic vesicle docking involved in exocytosis|synaptic vesicle docking during exocytosis The initial (indirect) attachment of a synaptic vesicle membrane to the presynaptic active zone membrane, mediated by proteins protruding from the membrane and proteins of the presynaptic active zone cytoplasmic component. Synaptic vesicle tethering is the first step in this process. GO:0016082 synaptic vesicle priming biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0016082 A process that converts synaptic vesicles to a state of competence for calcium triggered fusion with the active zone membrane by bringing the two membranes into very close proximity. Priming typically (but not always) occurs after docking (Jahn and Fasshauer, 2012). Primed vesicles are also capable of spontaneously fusing with the active zone membrane. GO:0016083 obsolete synaptic vesicle fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016083 synaptic vesicle fusion OBSOLETE. Fusion of the synaptic vesicle with the postsynaptic membrane. GO:0031698 beta-2 adrenergic receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031698 beta-2 adrenergic receptor ligand Interacting selectively and non-covalently with a beta-2 adrenergic receptor. GO:0031699 beta-3 adrenergic receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031699 beta-3 adrenergic receptor ligand Interacting selectively and non-covalently with a beta-3 adrenergic receptor. GO:0016077 sno(s)RNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016077 sno(s)RNA degradation|sno(s)RNA breakdown|sRNA catabolic process|sno(s)RNA catabolism|snoRNA catabolic process The chemical reactions and pathways resulting in the breakdown of snoRNA, small nucleolar RNA, any of a class of small RNAs that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins. GO:0031696 alpha-2C adrenergic receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031696 alpha-2C adrenergic receptor ligand Interacting selectively and non-covalently with an alpha-2C adrenergic receptor. GO:0016078 tRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016078 tRNA breakdown|tRNA catabolism|tRNA degradation The chemical reactions and pathways resulting in the breakdown of tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. GO:0031697 beta-1 adrenergic receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031697 beta-1 adrenergic receptor ligand Interacting selectively and non-covalently with a beta-1 adrenergic receptor. GO:0016079 synaptic vesicle exocytosis biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0016079 Fusion of intracellular membrane-bounded vesicles with the pre-synaptic membrane of the neuronal cell resulting in release of neurotransmitter into the synaptic cleft. GO:0031694 alpha-2A adrenergic receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031694 alpha-2A adrenergic receptor ligand Interacting selectively and non-covalently with an alpha-2A adrenergic receptor. GO:0031695 alpha-2B adrenergic receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031695 alpha-2B adrenergic receptor ligand Interacting selectively and non-covalently with an alpha-2B adrenergic receptor. GO:0016073 snRNA metabolic process biolink:BiologicalProcess go-plus goslim_drosophila|goslim_pombe http://purl.obolibrary.org/obo/GO_0016073 snRNA metabolism The chemical reactions and pathways involving snRNA, small nuclear RNA, any of various low-molecular-mass RNA molecules found in the eukaryotic nucleus as components of the small nuclear ribonucleoprotein. GO:0031692 alpha-1B adrenergic receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031692 alpha-1B adrenergic receptor ligand Interacting selectively and non-covalently with an alpha-1B adrenergic receptor. GO:0016074 sno(s)RNA metabolic process biolink:BiologicalProcess go-plus goslim_drosophila|goslim_pombe http://purl.obolibrary.org/obo/GO_0016074 snoRNA metabolism|box C/D sRNA metabolic process The chemical reactions and pathways involving snoRNA, small nucleolar RNA, any of a class of small RNAs that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins. They participate in the processing or modifications of many RNAs, mostly ribosomal RNAs (rRNAs) though snoRNAs are also known to target other classes of RNA, including spliceosomal RNAs, tRNAs, and mRNAs via a stretch of sequence that is complementary to a sequence in the targeted RNA. GO:0031693 alpha-1D adrenergic receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031693 alpha-1D adrenergic receptor ligand Interacting selectively and non-covalently with an alpha-1D adrenergic receptor. GO:0016075 rRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016075 rRNA catabolism|rRNA degradation|rRNA breakdown The chemical reactions and pathways resulting in the breakdown of rRNA, ribosomal RNA, a structural constituent of ribosomes. GO:0031690 adrenergic receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031690 adrenergic receptor ligand Interacting selectively and non-covalently with an adrenergic receptor. CHEBI:91079 purinergic receptor P2 antagonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_91079 GO:0016076 snRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016076 snRNA degradation|snRNA breakdown|snRNA catabolism The chemical reactions and pathways resulting in the breakdown of snRNA, small nuclear RNA, low-molecular-mass RNA molecules found in the eukaryotic nucleus as components of the small nuclear ribonucleoprotein. GO:0031691 alpha-1A adrenergic receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031691 alpha-1A adrenergic receptor ligand Interacting selectively and non-covalently with an alpha-1A adrenergic receptor. GO:0016050 vesicle organization biolink:BiologicalProcess go-plus goslim_yeast|goslim_pir http://purl.obolibrary.org/obo/GO_0016050 vesicle organization and biogenesis|vesicle organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle. GO:0031689 A3 adenosine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031689 A3 adenosine receptor ligand Interacting selectively and non-covalently with an A3 adenosine receptor. GO:0031687 A2A adenosine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031687 A2A adenosine receptor ligand Interacting selectively and non-covalently with an A2A adenosine receptor. GO:0031688 A2B adenosine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031688 A2B adenosine receptor ligand Interacting selectively and non-covalently with an A2B adenosine receptor. PATO:0001236 process quality biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PATO_0001236 quality of a process|quality of process|quality of occurrent|relational quality of occurrent A quality which inheres in an process. CHEBI:136389 5-[(9Z)-octadecenoyloxy]octadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136389 GO:0016048 detection of temperature stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016048 detection of temperature|perception of temperature|detection of thermal stimulus The series of events in which a temperature stimulus (hot or cold) is received and converted into a molecular signal. GO:0016049 cell growth biolink:BiologicalProcess go-plus gocheck_do_not_annotate|goslim_pir|goslim_plant|goslim_drosophila http://purl.obolibrary.org/obo/GO_0016049 non-developmental cell growth|metabolic process resulting in cell growth|cellular growth|cell expansion|non-developmental growth of a unicellular organism|metabolism resulting in cell growth|growth of cell The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present. GO:0016044 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016044 GO:0031685 adenosine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031685 adenosine receptor ligand Interacting selectively and non-covalently with an adenosine receptor. GO:0031686 A1 adenosine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031686 A1 adenosine receptor ligand Interacting selectively and non-covalently with an A1 adenosine receptor. GO:0016045 detection of bacterium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016045 detection of bacteria|perception of bacteria|perception of bacterium The series of events in which a stimulus from a bacterium is received and converted into a molecular signal. GO:0016046 detection of fungus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016046 detection of parasitic fungus|perception of parasitic fungus|detection of fungi|perception of parasitic fungi|detection of parasitic fungi|perception of fungus|perception of fungi The series of events in which a stimulus from a fungus is received and converted into a molecular signal. GO:0031683 G-protein beta/gamma-subunit complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031683 Interacting selectively and non-covalently with a complex of G-protein beta/gamma subunits. GO:0016047 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016047 GO:0031684 obsolete heterotrimeric G-protein complex cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031684 OBSOLETE. The series of molecular events that generate a signal through the activation of G-protein subunits and recycling of these subunits. GO:0016040 glutamate synthase (NADH) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016040 EC:1.4.1.14|MetaCyc:GLUTAMATE-SYNTHASE-NADH-RXN|RHEA:13753|KEGG_REACTION:R00093 L-glutamate:NAD+ oxidoreductase (transaminating)|NADH-glutamate synthase activity|NADH-dependent glutamate synthase activity|L-glutamate synthetase activity|GOGAT activity|glutamate (reduced nicotinamide adenine dinucleotide) synthase|NADH: GOGAT|L-glutamate synthase (NADH)|L-glutamate synthase activity Catalysis of the reaction: 2 L-glutamate + NAD(+) = 2-oxoglutarate + L-glutamine + H(+) + NADH. GO:0031681 G-protein beta-subunit binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031681 G-beta protein subunit binding Interacting selectively and non-covalently with a G-protein beta subunit. GO:0031682 G-protein gamma-subunit binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031682 G-gamma protein subunit binding Interacting selectively and non-covalently with a G-protein gamma subunit. GO:0016041 glutamate synthase (ferredoxin) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016041 MetaCyc:GLUTAMATE-SYNTHASE-FERREDOXIN-RXN|RHEA:12128|MetaCyc:PWY-4341|EC:1.4.7.1 L-glutamate:ferredoxin oxidoreductase (transaminating)|ferredoxin-glutamate synthase activity|ferredoxin-dependent glutamate synthase activity|glutamate synthase (ferredoxin-dependent) Catalysis of the reaction: 2 L-glutamate + 2 oxidized ferredoxin = L-glutamine + 2-oxoglutarate + 2 reduced ferredoxin + 2 H+. This is a two-step reaction: (a) L-glutamate + NH3 = L-glutamine + H2O, (b) L-glutamate + 2 oxidized ferredoxin + H2O = NH3 + 2-oxoglutarate + 2 reduced ferredoxin + 2 H+. GO:0016042 lipid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016042 Wikipedia:Lipid_catabolism lipid catabolism|multicellular organism lipid catabolic process|lipolysis|lipid degradation|lipid breakdown|multicellular organismal lipid catabolic process The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. GO:0031680 G-protein beta/gamma-subunit complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031680 G-beta/G-gamma complex|heterotrimeric G-protein GTPase, beta-subunit The heterodimer formed by the beta and gamma subunits of a heterotrimeric G protein, which dissociates from the alpha subunit upon guanine nuclotide exchange. GO:0016043 cellular component organization biolink:BiologicalProcess go-plus goslim_mouse|goslim_agr|goslim_pir|goslim_plant http://purl.obolibrary.org/obo/GO_0016043 cell organisation|cell organization and biogenesis|cellular component organisation in other organism|cellular component organisation at cellular level|cellular component organization in other organism|cellular component organization at cellular level A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component. GO:0016060 metarhodopsin inactivation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016060 The process in which metarhodopsin is prevented from generating molecular signals. Activated rhodopsin (R*) is inactivated by a two-step process: first, R* is phosphorylated by rhodopsin kinase which lowers the activity of R*. Second, the protein arrestin binds to phosphorylated R* to de-activate it. GO:0016061 regulation of light-activated channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016061 Any process that modulates the frequency, rate or extent of light-activated channel activity. GO:0031678 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031678 GO:0031679 NADH dehydrogenase (plastoquinone) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031679 NADH:plastoquinone reductase activity Catalysis of the reaction: NADH + H+ + plastoquinone = NAD+ + plastoquinol. GO:0031676 plasma membrane-derived thylakoid membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031676 plasma membrane thylakoid membrane The pigmented membrane of a plasma membrane-derived thylakoid. GO:0031677 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031677 GO:0065010 extracellular membrane-bounded organelle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0065010 extracellular membrane-enclosed organelle Organized structure of distinctive morphology and function, bounded by a lipid bilayer membrane and occurring outside the cell. PATO:0001241 physical object quality biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PATO_0001241 multiply inhering quality of a physical entity|quality of continuant|quality of a continuant|quality of an object|monadic quality of an object|monadic quality of continuant|quality of a single physical entity|monadic quality of a continuant A quality which inheres in a continuant. GO:0016059 deactivation of rhodopsin mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016059 rod response recovery|deactivation of rhodopsin mediated signalling The process of restoring the photoreceptor cell to its unexcited state after termination of the stimulus (photon). GO:0016055 Wnt signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016055 Wg signaling pathway|frizzled signaling pathway|Wnt receptor signalling pathway|Wingless signaling pathway|Wingless signalling pathway|Wnt-activated signaling pathway|frizzled signalling pathway|Wnt receptor signaling pathway|Wg signalling pathway The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state. GO:0031674 I band biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031674 Wikipedia:Sarcomere#bands I disc|J disc|isotropic disc A region of a sarcomere that appears as a light band on each side of the Z disc, comprising a region of the sarcomere where thin (actin) filaments are not overlapped by thick (myosin) filaments; contains actin, troponin, and tropomyosin; each sarcomere includes half of an I band at each end. GO:0016056 rhodopsin mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016056 rhodopsin signaling|rhodopsin mediated signalling pathway|rhodopsin mediated phototransduction The series of molecular signals generated as a consequence of excitation of rhodopsin by a photon and the events that convert the absorbed photons into a cellular response. GO:0031675 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031675 GO:0016057 regulation of membrane potential in photoreceptor cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016057 changes in polarization state of photoreceptor cell membrane Hyperpolarization (vertebrates) or depolarization (invertebrates) of the photoreceptor cell membrane via closing/opening of cation specific channels as a result of signals generated by rhodopsin activation by a photon. GO:0031672 A band biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031672 Wikipedia:Sarcomere#bands transverse disc|Q disc|anisotropic disc|A disc The dark-staining region of a sarcomere, in which myosin thick filaments are present; the center is traversed by the paler H zone, which in turn contains the M line. GO:0016058 maintenance of membrane potential in photoreceptor cell by rhodopsin mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016058 maintenance of rhodopsin mediated signaling|maintenance of rhodopsin mediated signalling Maintenance of the excited state of a photoreceptor cell to produce a steady-state current as a result of signals generated by rhodopsin activation by a photon. GO:0031673 H zone biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031673 Wikipedia:Sarcomere#bands H disc|H band A relatively pale zone traversing the center of the A band of a sarcomere, visible in relaxed muscle fibers; consists of the central portion of thick (myosin) filaments that are not overlapped by thin (actin) filaments. GO:0016051 carbohydrate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016051 anabolic carbohydrate metabolic process|carbohydrate anabolism|carbohydrate synthesis|carbohydrate formation|anabolic carbohydrate metabolism|carbohydrate biosynthesis The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. GO:0031670 cellular response to nutrient biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031670 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus. CHEBI:136398 N-acetyl-alpha-neuraminyl-(2->6)-beta-D-galactoside(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136398 GO:0031671 primary cell septum biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031671 A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a primary cell septum following nuclear division. GO:0016052 carbohydrate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016052 single-organism carbohydrate catabolic process|carbohydrate breakdown|catabolic carbohydrate metabolic process|catabolic carbohydrate metabolism|carbohydrate catabolism|multicellular organismal carbohydrate catabolic process|carbohydrate degradation The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. CHEBI:136396 4-O-[1-D-ribitylphosphono-(2R)-1-glycerylphosphono]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl ditrans,octacis-undecaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136396 GO:0016053 organic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016053 organic acid anabolism|organic acid synthesis|organic acid formation|organic acid biosynthesis The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage. GO:0016054 organic acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016054 organic acid breakdown|organic acid catabolism|organic acid degradation The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage. CHEBI:136397 (2xi)-3-deoxy-7-O-phosphonato-beta-D-threo-hept-6-ulopyranosonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136397 GO:0031669 cellular response to nutrient levels biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031669 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients. GO:0031667 response to nutrient levels biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031667 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients. GO:0031668 cellular response to extracellular stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031668 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus. GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031665 down-regulation of lipopolysaccharide-mediated signaling pathway|inhibition of lipopolysaccharide-mediated signaling pathway|negative regulation of lipopolysaccharide-mediated signalling pathway|negative regulation of LPS-mediated signaling pathway|down regulation of lipopolysaccharide-mediated signaling pathway|downregulation of lipopolysaccharide-mediated signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of signaling in response to detection of lipopolysaccharide. GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031666 up regulation of lipopolysaccharide-mediated signaling pathway|activation of lipopolysaccharide-mediated signaling pathway|stimulation of lipopolysaccharide-mediated signaling pathway|up-regulation of lipopolysaccharide-mediated signaling pathway|positive regulation of lipopolysaccharide-mediated signalling pathway|positive regulation of LPS-mediated signaling pathway|upregulation of lipopolysaccharide-mediated signaling pathway Any process that activates or increases the frequency, rate or extent of signaling in response to detection of lipopolysaccharide. GO:0090008 hypoblast development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090008 The process whose specific outcome is the progression of the hypoblast over time, from its formation to the mature structure. The hypoblast is a tissue formed from the inner cell mass that lies beneath the epiblast. CHEBI:136369 5-[(9Z)-hexadecenoyloxy]octadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136369 GO:0090009 primitive streak formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090009 The developmental process pertaining to the initial formation of the primitive streak from unspecified parts. The primitive streak is a ridge of cells running along the midline of the embryo where the mesoderm ingresses. It defines the anterior-posterior axis. GO:0090006 regulation of linear element assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090006 regulation of linear element assembly Any process that modulates the rate, frequency or extent of linear element assembly. Linear element assembly is the cell cycle process in which a proteinaceous scaffold, related to the synaptonemal complex, is assembled in association with S. pombe chromosomes during meiotic prophase. GO:0090007 obsolete regulation of mitotic anaphase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090007 regulation of mitotic anaphase OBSOLETE. Any process that modulates the frequency, rate or extent of mitotic anaphase, a cell cycle process comprising the steps by which a cell progresses through anaphase, the stage of mitosis during which the two sets of chromosomes separate and move away from each other. GO:0016026 obsolete proteasome endopeptidase core biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016026 proteasome endopeptidase core OBSOLETE. (Was not defined before being made obsolete). GO:0016027 inaD signaling complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016027 inaD signalling complex A complex of proteins that are involved in phototransduction and attached to the transient receptor potential (TRP) channel. The protein connections are mediated through inaD. GO:0016028 rhabdomere biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0016028 The specialized microvilli-containing organelle on the apical surfaces of a photoreceptor cell containing the visual pigment rhodopsin and most of the proteins involved in phototransduction. GO:0016029 subrhabdomeral cisterna biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016029 SMC|submicrovillar cisterna A membrane-bounded compartment that is found at the base of the rhabdomere and contains stored calcium, InsP3 receptors and smooth endoplasmic reticulum Ca2+-ATPase. GO:0016022 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016022 GO:0031663 lipopolysaccharide-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031663 lipopolysaccharide-mediated signalling pathway|LPS-mediated signaling pathway A series of molecular signals initiated by the binding of a lipopolysaccharide (LPS) to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Lipopolysaccharides are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system. GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031664 regulation of lipopolysaccharide-mediated signalling pathway|regulation of LPS-mediated signaling pathway Any process that modulates the frequency, rate or extent of signaling in response to detection of lipopolysaccharide. GO:0090001 replication fork arrest at tRNA locus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090001 A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the eukaryotic tRNA transcription unit. GO:0016023 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016023 GO:0031661 negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031661 G2/M-specific inhibition of cyclin-dependent protein kinase activity|negative regulation of cyclin-dependent protein kinase activity involved in G2/M|G2/M-specific down-regulation of cyclin-dependent protein kinase activity|negative regulation of cyclin-dependent protein kinase activity during G2/M|G2/M-specific down regulation of cyclin-dependent protein kinase activity|G2/M-specific downregulation of cyclin-dependent protein kinase activity|G2/M-specific negative regulation of cyclin-dependent protein kinase activity Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G2/M transition of the cell cycle. GO:0016024 CDP-diacylglycerol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016024 CDP-diacylglycerol anabolism|CDP-diacylglycerol synthesis|CDP-diacylglycerol formation|CDP-diacylglycerol biosynthesis The chemical reactions and pathways resulting in the formation of CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate. GO:0016025 obsolete proteasome endopeptidase regulator biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016025 proteasome endopeptidase regulator OBSOLETE. (Was not defined before being made obsolete). GO:0031662 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031662 GO:0090004 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090004 GO:0090005 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090005 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031660 G2/M-specific regulation of cyclin-dependent protein kinase activity|regulation of cyclin-dependent protein kinase activity involved in G2/M|regulation of cyclin-dependent protein kinase activity during G2/M Any process that modulates the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G2/M transition of the cell cycle. GO:0016020 membrane biolink:CellularComponent go-plus goslim_pir|goslim_plant|goslim_aspergillus|goslim_metagenomics|goslim_flybase_ribbon|goslim_chembl|goslim_yeast|goslim_candida http://purl.obolibrary.org/obo/GO_0016020 Wikipedia:Biological_membrane membrane region|whole membrane|region of membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. GO:0090002 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090002 GO:0016021 integral component of membrane biolink:CellularComponent go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0016021 Wikipedia:Transmembrane_protein integral to membrane|transmembrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0090003 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090003 GO:0031658 obsolete negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031658 negative regulation of cyclin-dependent protein kinase activity during G1/S|G1/S-specific down-regulation of cyclin-dependent protein kinase activity|G1/S-specific downregulation of cyclin-dependent protein kinase activity|G1/S-specific down regulation of cyclin-dependent protein kinase activity|G1/S-specific inhibition of cyclin-dependent protein kinase activity|negative regulation of cyclin-dependent protein kinase activity involved in G1/S|G1/S-specific negative regulation of cyclin-dependent protein kinase activity OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G1/S transition of the cell cycle. GO:0031659 obsolete positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031659 positive regulation of cyclin-dependent protein kinase activity during G1/S|G1/S-specific up regulation of cyclin-dependent protein kinase activity|positive regulation of cyclin-dependent protein kinase activity involved in G1/S|G1/S-specific upregulation of cyclin-dependent protein kinase activity|G1/S-specific stimulation of cyclin-dependent protein kinase activity|G1/S-specific positive regulation of cyclin-dependent protein kinase activity|G1/S-specific up-regulation of cyclin-dependent protein kinase activity|G1/S-specific activation of cyclin-dependent protein kinase activity OBSOLETE. Any process that activates or increases the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G1/S transition of the cell cycle. GO:0031656 positive regulation of heat dissipation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031656 up regulation of heat dissipation|upregulation of heat dissipation|stimulation of heat dissipation|activation of heat dissipation|up-regulation of heat dissipation Any process that activates or increases the rate or extent of heat dissipation. GO:0031657 obsolete regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031657 G1/S-specific regulation of cyclin-dependent protein kinase activity|regulation of cyclin-dependent protein kinase activity involved in G1/S|regulation of cyclin-dependent protein kinase activity during G1/S OBSOLETE. Any process that controls the frequency, rate or extent of G1 cyclin-dependent protein serine/threonine kinase activity contributing to the G1/S transition of the cell cycle. GO:0031654 regulation of heat dissipation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031654 Any process that modulates the rate or extent of heat dissipation. GO:0031655 negative regulation of heat dissipation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031655 downregulation of heat dissipation|down regulation of heat dissipation|inhibition of heat dissipation|down-regulation of heat dissipation Any process that stops, prevents, or reduces the rate or extent of heat dissipation. GO:0090019 obsolete regulation of transcription involved in anterior neural plate formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090019 OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter contributing to the formation of the anterior neural plate. GO:0090017 anterior neural plate formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090017 The formation of anterior end of the flat, thickened layer of ectodermal cells known as the neural plate. GO:0090018 posterior neural plate formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090018 The formation of posterior end of the flat, thickened layer of ectodermal cells known as the neural plate. GO:0016037 light absorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016037 absorption of light The reception of a photon by a cell. RO:0001025 located_in biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0001025 RO:0001025 GO:0016038 absorption of visible light biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016038 The reception of a (visible light) photon by a cell, visible light being defined as having a wavelength within the range 380-780 nm. GO:0016039 absorption of UV light biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016039 The reception of a (UV light) photon by a cell, UV light being defined as having a wavelength within the range 13.6-400 nm. GO:0090011 Wnt signaling pathway involved in primitive streak formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090011 Wnt receptor signalling pathway involved in primitive streak formation|Wnt-activated signaling pathway involved in primitive streak formation|Wnt receptor signaling pathway involved in primitive streak formation The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in transcription of target genes that contribute to the formation of the primitive streak. GO:0031652 positive regulation of heat generation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031652 up regulation of heat generation|activation of heat generation|stimulation of heat generation|up-regulation of heat generation|upregulation of heat generation Any process that activates or increases the rate or extent of heat generation. GO:0016033 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016033 GO:0090012 negative regulation of transforming growth factor beta receptor signaling pathway involved in primitive streak formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090012 negative regulation of transforming growth factor beta receptor signalling pathway involved in primitive streak formation Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway that contributes to the formation of the primitive streak. GO:0016034 maleylacetoacetate isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016034 RHEA:14817|UM-BBD_reactionID:r0106|EC:5.2.1.2|MetaCyc:MALEYLACETOACETATE-ISOMERASE-RXN|Reactome:R-HSA-71173 maleylacetoacetic isomerase activity|maleylacetone cis-trans-isomerase activity|maleylacetone isomerase activity|4-maleylacetoacetate cis-trans-isomerase activity Catalysis of the reaction: 4-maleylacetoacetate = 4-fumarylacetoacetate. GO:0031653 heat dissipation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031653 Any homeostatic process in which an organism releases excess heat to the environment, thereby lowering its internal temperature. CHEBI:136373 9-(octadecanoyloxy)octadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136373 GO:0031650 regulation of heat generation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031650 Any process that modulates the rate or extent of heat generation. GO:0016035 zeta DNA polymerase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016035 A heterodimeric DNA polymerase complex that catalyzes error-prone DNA synthesis in contexts such as translesion synthesis and double-stranded break repair. First characterized in Saccharomyces, in which the subunits are Rev3p and Rev7p; a third protein, Rev1p, is often associated with the polymerase dimer. CHEBI:136370 5-hydroxyoctadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136370 GO:0031651 negative regulation of heat generation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031651 downregulation of heat generation|down-regulation of heat generation|inhibition of heat generation|down regulation of heat generation Any process that stops, prevents, or reduces the rate or extent of heat generation. GO:0090010 transforming growth factor beta receptor signaling pathway involved in primitive streak formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090010 transforming growth factor beta receptor signalling pathway involved in primitive streak formation|TGFbeta signaling pathway involved in primitive streak formation A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to the formation of the primitive streak. GO:0016036 cellular response to phosphate starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016036 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of phosphate. GO:0090015 positive regulation of leaflet formation by auxin mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090015 positive regulation of leaflet formation by auxin mediated signalling pathway Any process that increases the frequency, rate or extent of leaflet formation as a result of the series of molecular signals generated in response to detection of auxin. GO:0090016 regulation of leaflet formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090016 Any process that modulates the frequency, rate or extent of leaflet formation. GO:0016030 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016030 GO:0016031 tRNA import into mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016031 cytoplasmic tRNA, mitochondrial import|cytoplasmic tRNA import into mitochondrion|mitochondrial import of cytoplasmic tRNA|cytoplasmic tRNA transport into mitochondrion|cytoplasmic tRNA import into mitochondria|nuclear-encoded tRNA import into mitochondrion The process in which a tRNA is transported from the cytosol, into the mitochondrial matrix. GO:0090013 regulation of transforming growth factor beta receptor signaling pathway involved in primitive streak formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090013 regulation of transforming growth factor beta receptor signalling pathway involved in primitive streak formation Any process that modulates the frequency, rate or extent of any TGF-beta receptor signaling pathway that contributes to the formation of the primitive streak. GO:0090014 leaflet formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090014 The developmental process pertaining to the initial formation of a leaflet from unspecified parts. A leaflet is one of the ultimate segments of a compound leaf. GO:0016032 viral process biolink:BiologicalProcess go-plus goslim_pir|goslim_metagenomics http://purl.obolibrary.org/obo/GO_0016032 Wikipedia:Viral_life_cycle virus process|virulence|viral infection A multi-organism process in which a virus is a participant. The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle. GO:0031649 heat generation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031649 Any homeostatic process in which an organism produces heat, thereby raising its internal temperature. GO:0031647 regulation of protein stability biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0031647 Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation. GO:0031648 protein destabilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031648 protein destabilisation|negative regulation of protein stability Any process that decreases the stability of a protein, making it more vulnerable to degradative processes or aggregation. GO:0031645 negative regulation of nervous system process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031645 negative regulation of neurological process|negative regulation of neurophysiological process|down-regulation of neurological process|negative regulation of neurological system process|downregulation of neurological process|down regulation of neurological process|inhibition of neurological process Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process. GO:0006689 ganglioside catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006689 ganglioside degradation|ganglioside catabolism|ganglioside breakdown The chemical reactions and pathways resulting in the breakdown of ganglioside, a ceramide oligosaccharide carrying, in addition to other sugar residues, one or more sialic residues. GO:0031646 positive regulation of nervous system process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031646 stimulation of neurological process|up-regulation of neurological process|activation of neurological process|positive regulation of neurological process|positive regulation of neurophysiological process|positive regulation of neurological system process|up regulation of neurological process|upregulation of neurological process Any process that activates or increases the frequency, rate or extent of a neurophysiological process. GO:0031643 positive regulation of myelination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031643 up regulation of myelination|activation of myelination|stimulation of myelination|up-regulation of myelination|upregulation of myelination Any process that activates or increases the frequency, rate or extent of the formation of a myelin sheath around nerve axons. GO:0006687 glycosphingolipid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006687 glycosphingolipid metabolism The chemical reactions and pathways involving glycosphingolipids, any compound with residues of sphingoid and at least one monosaccharide. GO:0006688 glycosphingolipid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006688 glycosphingolipid biosynthesis|glycosphingolipid anabolism|glycosphingolipid synthesis|glycosphingolipid formation The chemical reactions and pathways resulting in the formation of glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide. GO:0031644 regulation of nervous system process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031644 regulation of neurological system process|regulation of neurological process|regulation of neurophysiological process Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of the nervous system. CHEBI:42090 L-threitol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_42090 GO:0006685 sphingomyelin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006685 sphingomyelin degradation|sphingomyelin breakdown|sphingomyelin catabolism The chemical reactions and pathways resulting in the breakdown of sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine. GO:0006686 sphingomyelin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006686 sphingomyelin biosynthesis|sphingomyelin anabolism|sphingomyelin synthesis|sphingomyelin formation The chemical reactions and pathways resulting in the formation of sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine. GO:0006683 galactosylceramide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006683 galactosylceramide degradation|galactosylceramide catabolism|galactosylceramide breakdown The chemical reactions and pathways resulting in the breakdown of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group. GO:0006684 sphingomyelin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006684 sphingomyelin metabolism The chemical reactions and pathways involving sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine, any of a class of phospholipids in which the amino group of sphingosine is in amide linkage with one of several fatty acids, while the terminal hydroxyl group of sphingosine is esterified to phosphorylcholine. GO:0006681 galactosylceramide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006681 galactosylceramide metabolism The chemical reactions and pathways involving galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group. GO:0006682 galactosylceramide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006682 galactosylceramide synthesis|galactosylceramide formation|galactosylceramide biosynthesis|galactosylceramide anabolism The chemical reactions and pathways resulting in the formation of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group. GO:0006680 glucosylceramide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006680 glucosylceramide breakdown|glucosylceramide catabolism|glucosylceramide degradation The chemical reactions and pathways resulting in the breakdown of glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group. GO:0016008 major mitochondrial derivative biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016008 The larger of the two mitochondrial derivatives that arise by the unfolding of the Nebenkern during flagellum elongation; the major mitochondrial derivative is ovoid and darker than the minor derivative. RO:0001019 contains biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0001019 RO:0001019 GO:0016009 minor mitochondrial derivative biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016009 The smaller of the two mitochondrial derivatives that arise by the unfolding of the Nebenkern during flagellum elongation. GO:0016004 phospholipase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016004 Increases the activity of a phospholipase, an enzyme that catalyzes of the hydrolysis of a glycerophospholipid. RO:0001015 location_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0001015 RO:0001015 GO:0016005 phospholipase A2 activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016005 Increases the activity of the enzyme phospholipase A2. GO:0016006 Nebenkern biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016006 A product of the fusion of the mitochondria during spermatogenesis. After the completion of meiosis the mitochondria of the spermatid collect along side the nucleus and fuse into two masses; these wrap around each other to produce the spherical Nebenkern. During flagellum elongation the Nebenkern unfolds and the two derivatives (major and minor mitochondrial derivatives) elongate down the axoneme. GO:0016007 mitochondrial derivative biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016007 The major and minor mitochondrial derivatives are the mitochondria of the sperm tail and derive by the unfolding of the Nebenkern during flagellum elongation. GO:0016000 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016000 GO:0031641 regulation of myelination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031641 Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons. CHEBI:4372 (6S)-dehydrovomifoliol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_4372 GO:0031642 negative regulation of myelination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031642 down-regulation of myelination|inhibition of myelination|down regulation of myelination|downregulation of myelination Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a myelin sheath around nerve axons. GO:0016001 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016001 GO:0016002 sulfite reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016002 MetaCyc:SULFITE-REDUCTASE-RXN hydrogen-sulfide:(acceptor) oxidoreductase activity|siroheme sulfite reductase activity|assimilatory-type sulfite reductase activity|hydrogen-sulfide:acceptor oxidoreductase activity|sulphite reductase activity|assimilatory sulfite reductase activity Catalysis of the reaction: hydrogen sulfide + acceptor + 3 H2O = sulfite + reduced acceptor. GO:0031640 killing of cells of other organism biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0031640 killing of cells of another, non-host, organism|killing of cells of another organism Any process in an organism that results in the killing of cells of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions. GO:0016003 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016003 GO:0031638 zymogen activation biolink:BiologicalProcess go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0031638 zymogen activation by proteolytic cleavage The proteolytic processing of an inactive enzyme to an active form. GO:0031639 plasminogen activation biolink:BiologicalProcess go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0031639 cleavage of plasminogen to plasmin The process in which inactive plasminogen is processed to active plasmin. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide. GO:0031636 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031636 GO:0031637 regulation of neuronal synaptic plasticity in response to neurotrophin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031637 neurotrophin-induced neuronal synaptic plasticity The process in which a neurotrophic factor induces neuronal synaptic plasticity, the ability of neuronal synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers. GO:0031634 replication fork barrier binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031634 Interacting selectively and non-covalently with replication fork barriers, sites that inhibit the progress of replication forks. GO:0031635 adenylate cyclase-inhibiting opioid receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031635 opioid receptor, adenylate cyclase inhibiting pathway|inhibition of adenylate cyclase activity by opioid receptor signaling pathway|inhibition of adenylate cyclase activity by opioid receptor signalling pathway The series of molecular signals generated as a consequence of an opioid receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP). GO:0031632 positive regulation of synaptic vesicle fusion to presynaptic active zone membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031632 stimulation of synaptic vesicle fusion to presynaptic membrane|negative regulation of synaptic vesicle fusion to presynaptic membrane|up regulation of synaptic vesicle fusion to presynaptic active zone membrane|positive regulation of synaptic vesicle fusion to pre-synaptic membrane|up-regulation of synaptic vesicle fusion to presynaptic membrane|up-regulation of synaptic vesicle fusion to presynaptic active zone membrane|upregulation of synaptic vesicle fusion to presynaptic membrane|up regulation of synaptic vesicle fusion to presynaptic membrane|activation of synaptic vesicle fusion to presynaptic membrane Any process that activates or increases the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane. GO:0006698 obsolete ecdysone modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006698 ecdysone modification OBSOLETE. The covalent or conformational alteration of ecdysone, resulting in a change in its properties. GO:0031633 xanthophore biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031633 A chromatophore containing yellow pigment. GO:0006699 bile acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006699 bile acid anabolism|bile acid synthesis|bile acid biosynthesis|bile acid formation The chemical reactions and pathways resulting in the formation of bile acids, any of a group of steroid carboxylic acids occurring in bile. GO:0006696 ergosterol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006696 ergosterol anabolism|ergosterol synthesis|ergosterol formation|ergosterol biosynthesis The chemical reactions and pathways resulting in the formation of ergosterol, (22E)-ergosta-5,7,22-trien-3-beta-ol, a sterol found in ergot, yeast and moulds. GO:0006697 ecdysone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006697 ecdysone biosynthesis|ecdysone anabolism|ecdysone synthesis|ecdysone formation The chemical reactions and pathways resulting in the formation of ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects. GO:0006694 steroid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006694 Wikipedia:Steroid_metabolisms#Steroid_biosynthesis steroidogenesis|steroid anabolism|steroid biosynthesis|steroid synthesis|steroid formation The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification. GO:0006695 cholesterol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006695 cholesterol anabolism|cholesterol synthesis|cholesterol formation|cholesterol biosynthesis The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. CHEBI:42088 alpha-L-Fucp-(1->2)-beta-D-Galp-(1->4)-beta-D-GlcpNAc biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_42088 GO:0006692 prostanoid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006692 prostanoid metabolism The chemical reactions and pathways involving prostanoids, any compound based on or derived from the prostanoate structure. GO:0006693 prostaglandin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006693 prostaglandin metabolism The chemical reactions and pathways involving prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities. GO:0006690 icosanoid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006690 eicosanoid metabolic process|eicosanoid metabolism|icosanoid metabolism The chemical reactions and pathways involving icosanoids, any of a group of C20 polyunsaturated fatty acids. GO:0006691 leukotriene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006691 leukotriene metabolism The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid. GO:0016019 peptidoglycan immune receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016019 peptidoglycan receptor activity|peptidoglycan recognition activity Combining with a peptidoglycan and transmitting the signal to initiate an innate immune response. GO:0016015 morphogen activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016015 Acts as a trigger for a pattern specification process when present at a specific concentration within a gradient. GO:0016016 obsolete short-wave-sensitive opsin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016016 short-wave-sensitive opsin OBSOLETE. An opsin with maximal absorption between 400 and 500 nm. GO:0016017 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016017 GO:0016018 cyclosporin A binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016018 cyclophilin Interacting selectively and non-covalently with cyclosporin A, a cyclic undecapeptide that contains several N-methylated and unusual amino acids. GO:0031630 regulation of synaptic vesicle fusion to presynaptic active zone membrane biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0031630 regulation of synaptic vesicle fusion to pre-synaptic membrane|regulation of synaptic vesicle fusion to presynaptic membrane Any process that modulates the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane. GO:0016011 dystroglycan complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016011 A protein complex that includes alpha- and beta-dystroglycan, which are alternative products of the same gene; the laminin-binding component of the dystrophin-associated glycoprotein complex, providing a link between the subsarcolemmal cytoskeleton (in muscle cells) and the extracellular matrix. Alpha-dystroglycan is an extracellular protein binding to alpha-laminin and to beta-dystroglycan; beta-dystroglycan is a transmembrane protein which binds alpha-dystroglycan and dystrophin. CHEBI:136351 5,6-epoxy-(8Z,11Z,14Z)-icosatrienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136351 GO:0016012 sarcoglycan complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016012 sarcoglycan-sarcospan complex A protein complex formed of four sarcoglycans plus sarcospan; there are six known sarcoglycans: alpha-, beta-, gamma-, delta-, epsilon- and zeta-sarcoglycan; all are N-glycosylated single-pass transmembrane proteins. The sarcoglycan-sarcospan complex is a subcomplex of the dystrophin glycoprotein complex, and is fixed to the dystrophin axis by a lateral association with the dystroglycan complex. GO:0031631 negative regulation of synaptic vesicle fusion to presynaptic active zone membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031631 downregulation of synaptic vesicle fusion to presynaptic membrane|down-regulation of synaptic vesicle fusion to presynaptic active zone membrane|negative regulation of synaptic vesicle fusion to pre-synaptic active zone membrane|down-regulation of synaptic vesicle fusion to presynaptic membrane|negative regulation of synaptic vesicle fusion to presynaptic membrane|negative regulation of synaptic vesicle fusion to pre-synaptic membrane|inhibition of synaptic vesicle fusion to presynaptic membrane|down regulation of synaptic vesicle fusion to presynaptic active zone membrane|downregulation of synaptic vesicle fusion to presynaptic active zone membrane|down regulation of synaptic vesicle fusion to presynaptic membrane Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane. GO:0016013 syntrophin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016013 nitric oxide synthase-dystrophin complex, skeletal muscle A protein complex that includes alpha-, beta1-, beta2-syntrophins and syntrophin-like proteins; the syntrophin complex binds to the second half of the carboxy-terminal domain of dystrophin; also associates with neuronal nitric oxide synthase. GO:0016014 dystrobrevin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016014 A protein complex comprising alpha- and beta-dystrobrevin; forms part of the dystrophin glycoprotein complex. CHEBI:136354 (4Z,7Z,10Z,12E,16Z)-14-hydroperoxydocosapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136354 CHEBI:136355 5(S),6(S)-epoxy-18-hydroxy-(7E,9E,11Z,14Z,16E)-icosapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136355 CHEBI:136352 (7Z,10Z,13Z,15E,19Z)-17-hydroperoxydocosapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136352 GO:0016010 dystrophin-associated glycoprotein complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0016010 dystrophin glycoprotein complex|DGC A multiprotein complex that forms a strong mechanical link between the cytoskeleton and extracellular matrix; typical of, but not confined to, muscle cells. The complex is composed of transmembrane, cytoplasmic, and extracellular proteins, including dystrophin, sarcoglycans, dystroglycan, dystrobrevins, syntrophins, sarcospan, caveolin-3, and NO synthase. CHEBI:136353 (7Z,10Z,12E,16Z,19Z)-14-hydroperoxydocosapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136353 CHEBI:32700 arginine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32700 RO:0001000 derives_from biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0001000 RO:0001000 CHEBI:32702 L-tryptophanate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32702 CHEBI:32704 L-tryptophanium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32704 CHEBI:81672 (2S)-methylsuccinyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_81672 CHEBI:81671 (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E)-decaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_81671 CHEBI:91004 D-galactopyranose 6-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91004 CHEBI:91005 5-[(E)-caffeoyl]shikimate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91005 CHEBI:91007 aromatic carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91007 CHEBI:91000 resolvin E1(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91000 CHEBI:91001 18-oxoresolvin E1(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91001 OBO:GOCHE_23530 substance with cytokinin role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_23530 CHEBI:91002 sucrose 6(G)-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91002 CHEBI:91003 asperlicins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_91003 CHEBI:32716 D-tryptophanate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32716 CHEBI:32717 D-tryptophanium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32717 CHEBI:91020 actinorhodin(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91020 PR:000007988 gastric inhibitory polypeptide receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000007988 GIPR|glucose-dependent insulinotropic polypeptide receptor|GIP-R A glucagon-like receptor that is a translation product of the human GIPR gene or a 1:1 ortholog thereof. CL:0007010 preosteoblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0007010 osteoprogenitor cell Skeletogenic cell that has the potential to transform into an osteoblast, and develops from neural crest or mesodermal cells. CL:0007011 enteric neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0007011 Neuron that is part of the enteric nervous system. CHEBI:91025 erythropoietin inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_91025 CHEBI:91010 (2Z,4Z)-2,3-dichloromuconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_91010 CHEBI:91011 (2Z,4Z)-2,3-dichloromuconate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91011 CHEBI:91013 D-ribose 5-triphosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91013 CL:0007009 prechondroblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0007009 Skeletogenic cell that has the potential to develop into a chondroblast; and arises from neural crest, meseosdermal and notochordal and connective tissue cells. CL:0007005 notochordal cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0007005 Cell that is part of the notochord. CL:0007006 chordamesodermal cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0007006 axial mesodermal cell Mesodermal cell that is axially located and gives rise to the cells of the notochord. CL:0007003 preodontoblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0007003 Skeletogenic cell that has the potential to form an odontoblast, deposits predentine, and arises from a cranial neural crest cell. CL:0007004 premigratory neural crest cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0007004 Cell that is part of the neural crest region of the neuroepithelium, prior to migration. Note that not all premigratory neural crest cells may become migratory neural crest cells. CL:0007000 preameloblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0007000 Skeletogenic cell that has the potential to develop into an ameloblast. Located in the inner enamel epithelium, these cells elongate, their nuclei shift distally (away from the dental papilla), and their cytoplasm becomes filled with organelles needed for synthesis and secretion of enamel proteins. CHEBI:91036 phosphatidylinositol 36:3(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91036 GO:0016091 prenol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016091 prenol biosynthesis|prenol anabolism|prenol synthesis|prenol formation The chemical reactions and pathways resulting in the formation of prenols, isoprenoids of general formula (H-CH2-C(CH3)=CH-CH2-)n-OH, any primary monohydroxy alcohol whose carbon skeleton consists of two or more isoprenoid residues linked head to tail. GO:0016092 prenol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016092 prenol breakdown|prenol catabolism|prenol degradation The chemical reactions and pathways resulting in the breakdown of prenols, isoprenoids of general formula (H-CH2-C(CH3)=CH-CH2-)n-OH, any primary monohydroxy alcohol whose carbon skeleton consists of two or more isoprenoid residues linked head to tail. GO:0016093 polyprenol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016093 polyprenol metabolism The chemical reactions and pathways involving polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans. GO:0016094 polyprenol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016094 polyprenol anabolism|polyprenol synthesis|polyprenol formation|polyprenol biosynthesis The chemical reactions and pathways resulting in the formation of polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans. GO:0016090 prenol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016090 prenol metabolism The chemical reactions and pathways involving prenols, isoprenoids of general formula (H-CH2-C(CH3)=CH-CH2-)n-OH, any primary monohydroxy alcohol whose carbon skeleton consists of two or more isoprenoid residues linked head to tail. NCBITaxon:28009 Choanoflagellata organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_28009 Choanoflagellida|choanoflagellates|Choanozoa|Choanoflagellatea|Choanomonada GO:0016088 obsolete insulin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016088 insulin OBSOLETE. A polypeptide hormone that stimulates glucose uptake by muscle and adipose tissue, and promotes glycogenesis, lipogenesis and the synthesis of proteins and nucleic acids. GO:0016089 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016089 GO:0016084 myostimulatory hormone activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016084 The action characteristic of myostimulatory hormone, a peptide hormone that stimulates muscle contraction. GO:0016085 myoinhibitory hormone activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016085 The action characteristic of myostimulatory hormone, a peptide hormone that inhibits muscle contraction. GO:0016086 obsolete allatostatin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016086 allatostatin OBSOLETE. Peptide hormones produced by the corpora allata of insects that reversibly inhibit the production of juvenile hormone. GO:0016087 ecdysiostatic hormone activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016087 The action characteristic of ecdysiostatic hormone, a peptide hormone that inhibits ecdysone secretion. GO:0016099 monoterpenoid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016099 MetaCyc:PWY-3041 monoterpenoid anabolism|monoterpenoid synthesis|monoterpenoid formation|monoterpenoid biosynthesis The chemical reactions and pathways resulting in the formation of monoterpenoid compounds, terpenoids having a C10 skeleton. GO:0016095 polyprenol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016095 polyprenol catabolism|polyprenol degradation|polyprenol breakdown The chemical reactions and pathways resulting in the breakdown of polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans. GO:0016096 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016096 GO:0016097 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016097 GO:0016098 monoterpenoid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016098 monoterpenoid metabolism The chemical reactions and pathways involving monoterpenoid compounds, terpenoids having a C10 skeleton. CHEBI:17030 cycloartenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17030 CHEBI:32667 L-glutaminyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32667 CHEBI:32668 N(2)-L-glutamino group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32668 CHEBI:32660 asparaginate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32660 CHEBI:32661 asparaginium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32661 CHEBI:32664 asparagine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32664 CHEBI:32665 L-glutaminate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32665 CHEBI:17028 2-dehydro-3-deoxy-D-galactonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17028 CHEBI:17029 chitin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17029 CHEBI:32666 L-glutaminium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32666 CHEBI:17026 progesterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17026 CHEBI:17027 allysine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17027 CHEBI:17025 (S)-dihydroorotic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17025 CHEBI:17023 2-hydroxyadipic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17023 CHEBI:17020 glucomannan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17020 PR:000007928 glial cell line-derived neurotrophic factor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000007928 astrocyte-derived trophic factor|GDNF|ATF A protein that is a translation product of the human GDNF gene or a 1:1 ortholog thereof. CHEBI:17021 S-substituted glutathione biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17021 CHEBI:32678 glutaminate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32678 CHEBI:32679 glutaminium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32679 CHEBI:32672 D-glutaminate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32672 CHEBI:32673 D-glutaminium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32673 CHEBI:17019 (R)-amygdalin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17019 CHEBI:32674 D-glutaminyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32674 CHEBI:32675 N(2)-D-glutamino group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32675 CHEBI:32677 glutamine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32677 CHEBI:17015 riboflavin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17015 CHEBI:17016 L-methionine S-oxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17016 CHEBI:17013 dTMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17013 CHEBI:17011 5-dehydro-D-fructose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17011 CHEBI:17012 N-acetylneuraminic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17012 CHEBI:17010 S-inosyl-L-homocysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17010 CHEBI:17051 fluoride biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17051 CHEBI:17052 3-phosphoshikimic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17052 CHEBI:17050 3-phosphoglyceric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17050 CHEBI:32646 methioninium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32646 CHEBI:32648 methionine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32648 CHEBI:32640 D-methionyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32640 CHEBI:32644 methioninate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32644 CHEBI:17048 nororientaline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17048 CHEBI:17049 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17049 CHEBI:17047 all-trans-undecaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17047 CHEBI:17044 D-glucitol 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17044 CHEBI:17045 dinitrogen oxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17045 CHEBI:17042 tetrachlorohydroquinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17042 CHEBI:17043 biphenyl-2-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17043 CHEBI:17040 (carboxymethoxy)succinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17040 CHEBI:17041 (S)-N-methylcoclaurine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17041 CHEBI:32656 D-asparaginate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32656 CHEBI:32657 D-asparaginium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32657 CHEBI:32650 L-asparaginate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32650 CHEBI:32651 L-asparaginium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32651 CHEBI:32653 D-asparaginyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32653 CHEBI:17039 D-glucurono-6,2-lactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17039 CHEBI:17037 geissoschizine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17037 CHEBI:17038 fecosterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17038 CHEBI:17036 dibenzo[1,4]dioxine-2,3-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17036 CHEBI:17033 biliverdin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17033 CHEBI:17034 octadecanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17034 CHEBI:17031 chelirubine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17031 CHEBI:17032 2-dehydro-3-deoxy-D-gluconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17032 CHEBI:32623 D-leucinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32623 CHEBI:32624 D-leucinium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32624 PR:000007970 growth hormone receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000007970 GHR|somatotropin receptor|GH receptor A protein that is a translation product of the human GHR gene or a 1:1 ortholog thereof. PR:000007971 somatoliberin biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000007971 somatorelin|GHRF|growth hormone-releasing factor|growth hormone-releasing hormone|somatocrinin|sermorelin|GRF|GHRH A protein that is a translation product of the human GHRH gene or a 1:1 ortholog thereof. CHEBI:32626 D-leucino group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32626 CHEBI:32627 leucinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32627 CHEBI:32628 leucinium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32628 CHEBI:32629 leucino group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32629 CHEBI:32620 L-leucinium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32620 CHEBI:32622 L-leucino group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32622 CHEBI:81646 Pretetramid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_81646 CHEBI:32637 D-methioninate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32637 CHEBI:32638 D-methioninium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32638 PR:000007972 growth hormone-releasing hormone receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000007972 growth hormone-releasing factor receptor|GHRH receptor|GRF receptor|GHRHR|GRFR A glucagon-like receptor that is a translation product of the human GHRHR gene or a 1:1 ortholog thereof. CHEBI:32631 L-methioninate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32631 PR:000007973 appetite-regulating hormone biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000007973 growth hormone secretagogue|growth hormone-releasing peptide|protein M46|motilin-related peptide|MTLRP|GHRL A protein that is a translation product of the human GHRL gene or a 1:1 ortholog thereof. CHEBI:32632 L-methioninium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32632 CHEBI:32609 D-isoleucinium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32609 CHEBI:32604 L-isoleucinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32604 CHEBI:32605 L-isoleucinium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32605 CHEBI:32608 D-isoleucinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32608 CHEBI:17008 N(2)-acyl-L-glutamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17008 CHEBI:17009 GDP-L-fucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17009 CHEBI:17006 beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17006 CHEBI:32600 tetracene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32600 CHEBI:17007 1-(3,4-dimethoxyphenyl)ethane-1,2-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17007 CHEBI:17002 cholesteryl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17002 CHEBI:17000 tropate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17000 CHEBI:17001 7,8-dihydroneopterin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17001 CHEBI:81667 2-hydroxy-5-methylquinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_81667 CHEBI:32612 isoleucinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32612 CHEBI:32613 isoleucinium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32613 CHEBI:81666 4-methyl-5-nitrocatechol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_81666 CHEBI:32619 L-leucinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32619 GO:0031627 telomeric loop formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031627 T loop formation|T loop biosynthesis|t-loop biosynthesis|t-loop formation The process in which linear telomeric DNA is remodeled into duplex loops, by the invasion of a 3' single-stranded overhang into the duplex region. GO:0031628 opioid receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031628 Interacting selectively and non-covalently with an opioid receptor. GO:0006669 sphinganine-1-phosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006669 dihydrosphingosine-1-phosphate biosynthetic process|dihydrosphingosine-1-phosphate biosynthesis|sphinganine-1-phosphate biosynthesis|sphinganine-1-phosphate anabolism|sphinganine-1-phosphate synthesis|sphinganine-1-phosphate formation The chemical reactions and pathways resulting in the formation of sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol. GO:0031625 ubiquitin protein ligase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031625 ubiquitin ligase binding Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins. GO:0031626 beta-endorphin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031626 Interacting selectively and non-covalently with beta-endorphin, a peptide generated by the cleavage of pro-opiomelanocortin. GO:0006667 sphinganine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006667 dihydrosphingosine metabolic process|dihydrosphingosine metabolism|sphinganine metabolism The chemical reactions and pathways involving sphinganine, D-erythro-2-amino-1,3-octadecanediol. GO:0031623 receptor internalization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031623 A receptor-mediated endocytosis process that results in the movement of receptors from the plasma membrane to the inside of the cell. The process begins when cell surface receptors are monoubiquitinated following ligand-induced activation. Receptors are subsequently taken up into endocytic vesicles from where they are either targeted to the lysosome or vacuole for degradation or recycled back to the plasma membrane. GO:0031624 ubiquitin conjugating enzyme binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031624 Interacting selectively and non-covalently with a ubiquitin conjugating enzyme, any of the E2 proteins. GO:0006668 sphinganine-1-phosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006668 dihydrosphingosine-1-phosphate metabolism|sphinganine-1-phosphate metabolism|dihydrosphingosine-1-phosphate metabolic process The chemical reactions and pathways involving sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol. GO:0031621 negative regulation of fever generation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031621 down-regulation of fever|inhibition of fever|negative regulation of pyrexia|down regulation of fever|downregulation of fever Any process that stops, prevents, or reduces the rate or extent of fever generation. GO:0006665 sphingolipid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006665 sphingolipid metabolism The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). GO:0006666 3-keto-sphinganine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006666 3-keto-dihydrosphingosine metabolic process|3-keto-dihydrosphingosine metabolism|3-keto-sphinganine metabolism The chemical reactions and pathways involving 3-keto-sphinganine, a derivative of sphinganine with a ketone group at C3. It is an intermediate in the synthesis of sphingosine. GO:0031622 positive regulation of fever generation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031622 stimulation of fever|up-regulation of fever|positive regulation of pyrexia|upregulation of fever|up regulation of fever|activation of fever Any process that activates or increases the frequency, rate, or extent of fever generation. GO:0006663 platelet activating factor biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006663 platelet activating factor anabolism|platelet activating factor synthesis|PAF biosynthesis|PAF biosynthetic process|platelet activating factor formation|platelet activating factor biosynthesis The chemical reactions and pathways resulting in the formation of platelet activating factor, 1-O-alkyl-2-acetyl-sn-glycerol 3-phosphocholine, where alkyl = hexadecyl or octadecyl. Platelet activating factor is an inflammatory mediator released from a variety of cells in response to various stimuli. GO:0006664 glycolipid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006664 glycolipid metabolism The chemical reactions and pathways involving glycolipids, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). Some substances classified as bacterial glycolipids have the sugar group acylated by one or more fatty acids and the glycerol group may be absent. GO:0006661 phosphatidylinositol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006661 phosphatidylinositol synthesis|phosphatidylinositol formation|phosphoinositide biosynthetic process|phosphoinositide biosynthesis|phosphatidylinositol biosynthesis|PtdIns biosynthetic process|phosphatidylinositol anabolism|PtdIns biosynthesis The chemical reactions and pathways resulting in the formation of phosphatidylinositol, any glycophospholipid in which the sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol. GO:0006662 glycerol ether metabolic process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0006662 glycerol ether metabolism The chemical reactions and pathways involving glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol. GO:0006660 phosphatidylserine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006660 phosphatidylserine degradation|phosphatidylserine catabolism|phosphatidylserine breakdown The chemical reactions and pathways resulting in the breakdown of phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine. GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0031629 synaptic vesicle fusion|synaptic vesicle fusion to pre-synaptic membrane|synaptic vesicle fusion to presynaptic membrane Fusion of the membrane of a synaptic vesicle with the presynaptic active zone membrane, thereby releasing its cargo neurotransmitters into the synaptic cleft. CHEBI:136447 (Z)-1-(glutathione-S-yl)-2-phenylacetohydroximate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136447 CHEBI:136444 (E)-1-(glutathion-S-yl)-2-(indol-3-yl)acetohydroximate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136444 CHEBI:136445 1-aci-nitro-2-(1H-indol-3-yl)ethane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136445 CHEBI:136448 Cer(d18:0/18:1) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136448 GO:0031620 regulation of fever generation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031620 regulation of pyrexia Any process that modulates the rate or extent of fever generation. CHEBI:136442 desulfoglucosinolic acid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136442 CHEBI:136443 (5Z,8Z,11Z,17Z)-14,15-epoxyicosatetraenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136443 CHEBI:136440 beta-D-thioglucoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136440 CHEBI:136441 (5Z,8Z,14Z,17Z)-11,12-epoxyicosatetraenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136441 GO:0031616 spindle pole centrosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031616 A centrosome from which one pole of a mitotic or meiotic spindle is organized. GO:0031617 NMS complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031617 Ndc80-MIND-Spc7 complex|KNL-1-Mis12-Ndc80|KMN kinetochore network A supercomplex formed by the association of two subcomplexes (known as MIND and Ndc80 in Schizosaccharomyces) with additional proteins at the kinetochores of condensed nuclear chromosomes. GO:0031614 obsolete ER proteasome regulatory particle, lid subcomplex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031614 OBSOLETE. The subunits that form the peripheral lid of the regulatory particle of a proteasome located in the endoplasmic reticulum of a cell. GO:0031615 cytosolic proteasome regulatory particle, lid subcomplex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031615 The subcomplex of the cytosolic proteasome regulatory particle that forms the peripheral lid, which is added on top of the base subcomplex. GO:0031612 cytosolic proteasome regulatory particle, base subcomplex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031612 The subcomplex of the proteasome regulatory particle that directly associates with the proteasome core complex located in the cytosol of the cell. GO:0006678 glucosylceramide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006678 glucosylceramide metabolism The chemical reactions and pathways involving glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group. They are neutral glycolipids containing equimolar amounts of fatty acid, glucose, and sphingosine or a sphingosine derivative. GO:0031613 nuclear proteasome regulatory particle, lid subcomplex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031613 The subunits that form the peripheral lid of the regulatory particle of a proteasome located in the nucleus of a cell. GO:0006679 glucosylceramide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006679 glucosylceramide synthesis|glucosylceramide formation|glucosylceramide biosynthesis|glucosylceramide anabolism The chemical reactions and pathways resulting in the formation of glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group. GO:0006676 mannosyl diphosphorylinositol ceramide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006676 M(IP)2C metabolic process|M(IP)2C metabolism|mannosyl diphosphorylinositol ceramide metabolism The chemical reactions and pathways involving mannosyl diphosphorylinositol ceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains two phosphoryl (-P(O)=) groups and a mannose derivative. GO:0031610 nuclear proteasome regulatory particle, base subcomplex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031610 The subunits of the regulatory particle that directly associate with the core complex of a proteasome located in the nucleus of a cell. GO:0031611 obsolete ER proteasome regulatory particle, base subcomplex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031611 OBSOLETE. The subunits of the regulatory particle that directly associate with the core complex of a proteasome located in the endoplasmic reticulum of a cell. GO:0006677 glycosylceramide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006677 glycosylceramide metabolism The chemical reactions and pathways involving glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group. GO:0006674 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006674 GO:0006675 mannosyl-inositol phosphorylceramide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006675 mannose-inositol-P-ceramide (MIPC) metabolism|mannose inositol phosphoceramide metabolism|MIPC metabolism|mannosyl-inositol-phosphorylceramide metabolism|MIPC metabolic process|mannose inositol phosphoceramide metabolic process|mannose-inositol-P-ceramide (MIPC) metabolic process The chemical reactions and pathways involving mannosyl-inositol phosphorylceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains a phosphoryl (-P(O)=) groups and a mannose derivative. GO:0006672 ceramide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006672 ceramide metabolism The chemical reactions and pathways involving ceramides, any N-acylated sphingoid. GO:0006673 inositol phosphoceramide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006673 inositol phosphorylceramide metabolic process|inositol phosphorylceramide metabolism|inositolphosphoceramide metabolism The chemical reactions and pathways involving inositol phosphoceramides, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group. GO:0006670 sphingosine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006670 sphing-4-enine metabolic process|(4E)-sphing-4-enine metabolic process|sphingosine metabolism|(4E)-sphing-4-enine metabolism|sphing-4-enine metabolism The chemical reactions and pathways involving sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues. GO:0006671 phytosphingosine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006671 phytosphingosine metabolism The chemical reactions and pathways involving phytosphingosine, (2S,3S,4R)-2-aminooctadecane-1,3,4-triol, a constituent of many plant sphingolipids. GO:0031618 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031618 GO:0031619 homologous chromosome orientation involved in meiotic metaphase I plate congression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031619 homologous chromosome orientation during meiosis|homologous chromosome orientation during meiosis I The cell cycle process in which the sister centromeres of one chromosome attach to microtubules that emanate from the same spindle pole, which ensures that homologous maternal and paternal chromosomes are pulled in opposite directions at anaphase of meiosis I. CHEBI:136456 glycolaldehyde phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136456 CHEBI:17099 aspulvinone H biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17099 CHEBI:17097 biphenyl biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17097 CHEBI:17098 veratraldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17098 GO:0031605 obsolete ER proteasome core complex, alpha-subunit complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031605 OBSOLETE. The subunits forming the outer ring of the core complex of a proteasome located in the endoplasmic reticulum of a cell. GO:0006649 phospholipid transfer to membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006649 The transfer of a phospholipid from its site of synthesis to the plasma membrane. GO:0031606 cytosolic proteasome core complex, alpha-subunit complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031606 The proteasome core subcomplex that constitutes the two outer rings of the cytosolic proteasome core complex. GO:0006647 phosphatidyl-N-monomethylethanolamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006647 phosphatidyl-N-monomethylethanolamine anabolism|phosphatidyl-N-monomethylethanolamine biosynthesis|phosphatidyl-N-monomethylethanolamine synthesis|phosphatidyl-N-monomethylethanolamine formation|PMME biosynthetic process|PMME biosynthesis The chemical reactions and pathways involving phosphatidyl-N-monomethylethanolamine (PMME), a derivative of phosphatidylethanolamine with a methylated amine group. GO:0031603 cytosolic proteasome core complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031603 The core complex of a proteasome located in the cytosol of a cell. GO:0006648 dihydrosphingosine-1-P pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006648 A phosphatidylethanolamine biosynthetic process that proceeds via the enzymatic action of dihydrosphingosine phosphate lyase. GO:0031604 nuclear proteasome core complex, alpha-subunit complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031604 The subunits forming the outer ring of the core complex of a proteasome located in the nucleus of a cell. GO:0031601 nuclear proteasome core complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031601 The core complex of a proteasome located in the nucleus of a cell. GO:0006645 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006645 GO:0006646 phosphatidylethanolamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006646 phosphatidylethanolamine anabolism|phosphatidylethanolamine synthesis|phosphatidylethanolamine formation|phosphatidylethanolamine biosynthesis The chemical reactions and pathways resulting in the formation of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine. GO:0031602 obsolete ER proteasome core complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031602 OBSOLETE. The core complex of a proteasome located in the endoplasmic reticulum of a cell. GO:0006643 membrane lipid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006643 membrane lipid metabolism The chemical reactions and pathways involving membrane lipids, any lipid found in or associated with a biological membrane. GO:0006644 phospholipid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006644 phospholipid metabolism The chemical reactions and pathways involving phospholipids, any lipid containing phosphoric acid as a mono- or diester. GO:0031600 cytosolic proteasome regulatory particle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031600 A multisubunit complex located in the cytosol of a cell, which caps one or both ends of the proteasome core complex. This complex recognizes, unfolds ubiquitinated proteins and translocates them to the proteasome core complex. GO:0006641 triglyceride metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006641 triacylglycerol metabolic process|triacylglycerol metabolism|triglyceride metabolism The chemical reactions and pathways involving triglyceride, any triester of glycerol. The three fatty acid residues may all be the same or differ in any permutation. Triglycerides are important components of plant oils, animal fats and animal plasma lipoproteins. GO:0006642 triglyceride mobilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006642 triacylglycerol mobilization The release of triglycerides, any triester of glycerol, from storage within cells or tissues, making them available for metabolism. GO:0006640 monoacylglycerol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006640 monoglyceride biosynthesis|monoglyceride biosynthetic process|monoacylglycerol biosynthesis|monoacylglycerol anabolism|monoacylglycerol synthesis|monoacylglycerol formation The chemical reactions and pathways resulting in the formation of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified. GO:0031609 cytosolic proteasome core complex, beta-subunit complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031609 The proteasome core subcomplex that constitutes the two inner rings of the cytosolic proteasome core complex. GO:0031607 nuclear proteasome core complex, beta-subunit complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031607 The subunits forming the inner ring of the core complex of a proteasome located in the nucleus of a cell. GO:0031608 obsolete ER proteasome core complex, beta-subunit complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031608 OBSOLETE. The subunits forming the inner ring of the core complex of a proteasome located in the endoplasmic reticulum of a cell. CHEBI:136424 (E)-omega-[(methylsulfanyl)alkyl]thiohydroximate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136424 CHEBI:136425 omega-(methylsulfanyl)alkyl desulfoglucosinolate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136425 CHEBI:136422 (Z)-desulfoglucotropeolin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136422 CHEBI:136428 N-hydroxyimidothioate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136428 PATO:0001199 linear biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PATO_0001199 CHEBI:136420 3'-end 5'-phosphate-ribonucleotide(3-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136420 GO:0006658 phosphatidylserine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006658 phosphatidylserine metabolism The chemical reactions and pathways involving phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine. They are important constituents of cell membranes. GO:0006659 phosphatidylserine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006659 phosphatidylserine anabolism|phosphatidylserine synthesis|phosphatidylserine formation|phosphatidylserine biosynthesis The chemical reactions and pathways resulting in the formation of phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine. GO:0006656 phosphatidylcholine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006656 phosphatidylcholine biosynthesis|phosphatidylcholine anabolism|phosphatidylcholine synthesis|phosphatidylcholine formation The chemical reactions and pathways resulting in the formation of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. GO:0006657 CDP-choline pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006657 MetaCyc:PWY3O-450 Kennedy pathway|phosphatidylcholine biosynthesis from choline The phosphatidylcholine biosynthetic process that begins with the phosphorylation of choline and ends with the combination of CDP-choline with diacylglycerol to form phosphatidylcholine. GO:0006654 phosphatidic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006654 phosphatidic acid biosynthesis|phosphatidic acid anabolism|phosphatidic acid synthesis|phosphatidic acid formation The chemical reactions and pathways resulting in the formation of phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids. GO:0006655 phosphatidylglycerol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006655 phosphatidylglycerol anabolism|phosphatidylglycerol synthesis|phosphatidylglycerol formation|phosphatidylglycerol biosynthesis The chemical reactions and pathways resulting in the formation of phosphatidylglycerols, any of a class of phospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol. GO:0006652 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006652 GO:0006653 1,2-diacyl-sn-glycero-3-phosphocholine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006653 lecithin metabolic process|1,2-diacyl-sn-glycero-3-phosphocholine metabolism The chemical reactions and pathways involving any 1,2-diacyl-sn-glycero-3-phosphocholine, the compounds most commonly designated lecithin. GO:0006650 glycerophospholipid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006650 glycerophospholipid metabolism|alpha-glycerophosphate pathway|phosphoglyceride metabolic process|phosphoglyceride metabolism The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue. GO:0006651 diacylglycerol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006651 diacylglycerol anabolism|diacylglycerol synthesis|diacylglycerol formation|diglyceride biosynthesis|diacylglycerol biosynthesis The chemical reactions and pathways resulting in the formation of diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group. CHEBI:136435 omega-[(methylsulfinyl)alkyl]glucosinolate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136435 CHEBI:136436 2-hydroxy-(indol-3-yl)acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136436 CHEBI:136433 2,5-diimino-3,4-bis(indol-3-yl)hexanedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136433 CHEBI:136434 omega-[(methylsulfanyl)alkyl]glucosinolate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136434 CHEBI:136439 (5Z,11Z,14Z,17Z)-8,9-epoxyicosatetraenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136439 CHEBI:136437 3,4-bis(7-chloroindol-3-yl)-2,5-diiminohexanedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136437 CHEBI:136438 D-thioglucoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136438 CHEBI:136432 (E)-2-(indol-3-yl)-1-thioacetohydroximate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136432 GO:0006627 protein processing involved in protein targeting to mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006627 mitochondrial processing|mitochondrial protein processing during import The cleavage of peptide bonds in proteins, usually near the N terminus, contributing to the process of import into the mitochondrion. Several different peptidases mediate cleavage of proteins destined for different mitochondrial compartments. CHEBI:17073 Cypridina luciferin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17073 GO:0006628 obsolete mitochondrial translocation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006628 mitochondrial translocation OBSOLETE. The translocation of proteins across the mitochondrial membrane. In the presence of a translocating chain, the outer membrane import machinery (MOM complex) and the inner membrane import machinery (MIM complex) form translocation contact sites as a part of the membrane preprotein import machinery. CHEBI:17074 cycasin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17074 CHEBI:17071 glycolaldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17071 GO:0006625 protein targeting to peroxisome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006625 protein-peroxisome targeting The process of directing proteins towards the peroxisome, usually using signals contained within the protein. GO:0006626 protein targeting to mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006626 mitochondrial translocation|protein import into mitochondrion|protein targeting to mitochondria|mitochondrial protein import|protein-mitochondrial targeting The process of directing proteins towards and into the mitochondrion, usually mediated by mitochondrial proteins that recognize signals contained within the imported protein. CHEBI:17072 N-amidino-L-aspartic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17072 GO:0006623 protein targeting to vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006623 protein-vacuolar targeting|vacuolar protein sorting|protein vacuolar targeting|protein-vacuole targeting The process of directing proteins towards the vacuole, usually using signals contained within the protein. GO:0006624 vacuolar protein processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006624 vacuolar protein maturation|vacuolar proteolysis Protein processing that takes place in the vacuole. Most protein processing in the vacuole represents proteolytic cleavage of precursors to form active enzymes. GO:0006621 protein retention in ER lumen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006621 maintenance of protein location in ER lumen The retention in the endoplasmic reticulum (ER) lumen of soluble resident proteins. Sorting receptors retrieve proteins with ER localization signals, such as KDEL and HDEL sequences or some transmembrane domains, that have escaped to the cis-Golgi network and return them to the ER. Abnormally folded proteins and unassembled subunits are also selectively retained in the ER. GO:0006622 protein targeting to lysosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006622 protein-lysosome targeting The process of directing proteins towards the lysosome using signals contained within the protein. GO:0006620 posttranslational protein targeting to endoplasmic reticulum membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006620 posttranslational endoplasmic reticulum protein-membrane targeting|SRP-independent endoplasmic reticulum protein-membrane targeting|posttranslational endoplasmic reticulum membrane targeting|posttranslational protein endoplasmic reticulum membrane targeting|posttranslational protein targeting to ER membrane The targeting of proteins to a membrane that occurs after their translation. Some secretory proteins exhibit posttranslational transport into the endoplasmic reticulum (ER) lumen: they are synthesized in their entirety on free cytosolic ribosomes and then released into the cytosol, where they are bound by chaperones which keep them in an unfolded state, and subsequently are translocated across the ER membrane. CHEBI:136408 12-hydroxy-(5Z,8Z,10E,14Z)-icosatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136408 CHEBI:136409 15-hydroxy-(5Z,8Z,11Z,13E)-icosatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136409 CHEBI:136400 8(S),15(S)-DiHPETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136400 CHEBI:136401 14(R),15(S)-DiHPETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136401 CHEBI:136406 13-hydroxyoctadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136406 CHEBI:4439 dermatan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_4439 CHEBI:136407 5-hydroxy-(6E,8Z,11Z,14Z)-icosatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136407 CHEBI:17068 3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17068 CHEBI:17069 3-hydroxybenzyl alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17069 CHEBI:4431 deoxyribonucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_4431 CHEBI:17066 (R)-3-hydroxybutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17066 GO:0006629 lipid metabolic process biolink:BiologicalProcess go-plus goslim_plant|goslim_pir|goslim_drosophila|goslim_aspergillus|goslim_metagenomics|goslim_generic|goslim_pombe|goslim_chembl|goslim_mouse|goslim_yeast|goslim_candida|goslim_agr http://purl.obolibrary.org/obo/GO_0006629 Wikipedia:Lipid_metabolism lipid metabolism The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids. CHEBI:17064 4-nitroaniline biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17064 CHEBI:17065 3',5'-cyclic CMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17065 GO:0006638 neutral lipid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006638 neutral lipid metabolism The chemical reactions and pathways involving neutral lipids, lipids only soluble in solvents of very low polarity. CHEBI:17062 primary aliphatic amine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17062 CHEBI:17063 L-erythrulose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17063 GO:0006639 acylglycerol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006639 glyceride metabolic process|glyceride metabolism|acylglycerol metabolism The chemical reactions and pathways involving acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids. GO:0006636 unsaturated fatty acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006636 MetaCyc:PWY-762|MetaCyc:PWY-782 unsaturated fatty acid formation|fatty acid desaturation|unsaturated fatty acid biosynthesis|unsaturated fatty acid anabolism|unsaturated fatty acid synthesis|polyunsaturated fatty acid biosynthesis The chemical reactions and pathways resulting in the formation of an unsaturated fatty acid, any fatty acid containing one or more double bonds between carbon atoms. GO:0006637 acyl-CoA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006637 acyl-CoA metabolism The chemical reactions and pathways involving acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with an acyl group. CHEBI:17061 D-glutamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17061 GO:0006634 hexadecanal biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006634 palmitaldehyde biosynthesis|palmitaldehyde biosynthetic process|hexadecanal anabolism|hexadecanal synthesis|hexadecanal formation|hexadecanal biosynthesis The chemical reactions and pathways resulting in the formation of hexadecanal, the C16 straight chain aldehyde. GO:0006635 fatty acid beta-oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006635 A fatty acid oxidation process that results in the complete oxidation of a long-chain fatty acid. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and occurs by successive cycles of reactions during each of which the fatty acid is shortened by a two-carbon fragment removed as acetyl coenzyme A; the cycle continues until only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively). GO:0006632 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006632 GO:0006633 fatty acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006633 MetaCyc:PWY-5156|MetaCyc:PWY-4381|MetaCyc:FASYN-INITIAL-PWY|Wikipedia:Fatty_acid_synthesis fatty acid synthesis|fatty acid formation|fatty acid biosynthesis|fatty acid anabolism The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes. GO:0006630 obsolete lipid binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006630 lipid binding OBSOLETE. (Was not defined before being made obsolete). GO:0006631 fatty acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006631 Wikipedia:Fatty_acid_metabolism fatty acid metabolism The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis. CHEBI:42027 1,2-di-[(9Z,12Z)-octadecadienoyl]-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_42027 CHEBI:136419 3'-end 2'-deoxyribonucleotide-3'-diphospho-5'-guanosine(3-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136419 CHEBI:136413 adenosine-5'-diphospho-5'-(2'-deoxyribonucleotide) residue(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136413 CHEBI:136414 adenosine-5'-diphospho-5'-ribonucleotide-2'-deoxyribonucleotide residue(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136414 CHEBI:136411 (4Z,7Z,10Z,13Z,16Z,19S,20R)-19,20-epoxydocosapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136411 CHEBI:136412 5'-end 2'-deoxyribonucleotide(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136412 CHEBI:136418 guanosine-5'-diphospho-5'-(2'-deoxyribonucleotide)(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136418 CHEBI:136415 5'-phosphate ribonucleotide-(2'-deoxyribonucleotide) residue(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136415 NCBITaxon:716545 saccharomyceta organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_716545 CHEBI:136416 5'-end 2'-deoxyribonucleoside residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136416 CHEBI:17059 2-methylcholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17059 CHEBI:17057 cellobiose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17057 CHEBI:17058 3-dehydroecdysone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17058 CHEBI:136410 (4Z,7Z,10Z,13Z,16Z,19R,20S)-19,20-epoxydocosapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136410 CHEBI:17056 1-carboxyvinyl carboxyphosphonate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17056 CHEBI:17053 L-aspartic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17053 GO:0006605 protein targeting biolink:BiologicalProcess go-plus goslim_drosophila|goslim_generic|goslim_pombe|goslim_chembl|goslim_yeast http://purl.obolibrary.org/obo/GO_0006605 Wikipedia:Protein_targeting nascent polypeptide association|protein sorting along secretory pathway The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif. CHEBI:17095 cis-1,6-dihydroxy-4-methylcyclohexa-2,4-dienecarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17095 GO:0006606 protein import into nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006606 protein transport from cytoplasm to nucleus|protein import into cell nucleus|establishment of protein localization to nucleus|protein nucleus import The directed movement of a protein from the cytoplasm to the nucleus. CHEBI:17096 strictosidine aglycone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17096 GO:0006603 phosphocreatine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006603 phosphocreatine metabolism The chemical reactions and pathways involving phosphocreatine, a phosphagen of creatine present in high concentration in striated muscle which is synthesized and broken down by creatine phosphokinase to buffer ATP concentration. It acts as an immediate energy reserve for muscle. GO:0006604 phosphoarginine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006604 phosphoarginine metabolism The chemical reactions and pathways involving phosphoarginine, a phosphagen of L-arginine with phosphoric acid containing the phosphoamide bond. It is a source of energy in the contraction of muscle in invertebrates, corresponding to phosphocreatine in the muscles of vertebrates. CHEBI:17094 2-dehydropantoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17094 GO:0006601 creatine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006601 creatine formation|creatine biosynthesis|creatine anabolism|creatine synthesis The chemical reactions and pathways resulting in the formation of creatine, N-[amino(imino)methyl]-N-methylglycine. Creatine is formed by a process beginning with amidino group transfer from L-arginine to glycine to form guanidinoacetate, followed by methyl group transfer from S-adenosyl-L-methionine to guanidinoacetate; it is then is phosphorylated to form a pool that stores high energy phosphate for the replenishment of ATP during periods of high, or fluctuating energy demand. In animals, most creatine is transported to and used in muscle. GO:0006602 creatinine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006602 creatinine catabolism|creatinine degradation|creatinine breakdown The chemical reactions and pathways resulting in the breakdown of creatinine, 2-amino-1,5-dihydro-1-methyl-4H-imidazol-4-one, an end product of creatine metabolism and a normal constituent of urine. CHEBI:17092 3-chloro-D-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17092 GO:0006600 creatine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006600 creatine metabolism The chemical reactions and pathways involving creatine (N-(aminoiminomethyl)-N-methylglycine), a compound synthesized from the amino acids arginine, glycine, and methionine that occurs in muscle. CHEBI:17090 (1R,2R,3R)-prephytoene diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17090 CHEBI:32689 D-argininium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32689 CHEBI:32681 L-argininate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32681 CHEBI:32682 L-argininium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32682 CHEBI:32683 L-argininium(2+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32683 CHEBI:32684 L-arginyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32684 CHEBI:42017 2,4-dinitrophenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_42017 CHEBI:32688 D-argininate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32688 CHEBI:17088 monoacyl-sn-glycerol 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17088 GO:0006609 obsolete mRNA-binding (hnRNP) protein import into nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006609 mRNA-binding (hnRNP) protein-nucleus import|mRNA-binding (hnRNP) protein import into cell nucleus|mRNA-binding (hnRNP) protein transport from cytoplasm to nucleus OBSOLETE. The directed movement of a heterogeneous nuclear ribonucleoprotein from the cytoplasm into the nucleus, across the nuclear membrane. CHEBI:17089 glycoprotein biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17089 GO:0006607 NLS-bearing protein import into nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006607 NLS-bearing substrate-nucleus import|NLS-bearing substrate import into cell nucleus|NLS-bearing substrate import into nucleus|NLS-bearing substrate transport from cytoplasm to nucleus The directed movement of a protein bearing a nuclear localization signal (NLS) from the cytoplasm into the nucleus, across the nuclear envelope. CHEBI:17087 ketone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17087 GO:0006608 obsolete snRNP protein import into nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006608 snRNP protein-nucleus import|snRNP protein import into cell nucleus|snRNP protein transport from cytoplasm to nucleus OBSOLETE. The directed movement of a small nuclear ribonucleoprotein from the cytoplasm into the nucleus, across the nuclear membrane. GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006616 SRP-dependent cotranslational membrane targeting, translocation|SRP-dependent cotranslational protein-membrane targeting, translocation|translocation during SRP-dependent cotranslational protein targeting to membrane|ER translocation The process during cotranslational membrane targeting wherein proteins move across a membrane. SRP and its receptor initiate the transfer of the nascent chain across the endoplasmic reticulum (ER) membrane; they then dissociate from the chain, which is transferred to a set of transmembrane proteins, collectively called the translocon. Once the nascent chain translocon complex is assembled, the elongating chain passes directly from the large ribosomal subunit into the centers of the translocon, a protein-lined channel within the membrane. The growing chain is never exposed to the cytosol and does not fold until it reaches the ER lumen. CHEBI:17084 2-hydroxyglutaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17084 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006617 signal sequence recognition during SRP-dependent cotranslational protein targeting to membrane|SRP-dependent cotranslational membrane targeting, signal sequence recognition|SRP-dependent cotranslational protein-membrane targeting, signal sequence recognition The process in which SRP binds to the signal peptide in a nascent protein, causing protein elongation to pause, during cotranslational membrane targeting. GO:0006614 SRP-dependent cotranslational protein targeting to membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006614 SRP-dependent cotranslational membrane targeting|ER translocation|SRP-dependent cotranslational protein-membrane targeting The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane. CHEBI:17082 L-2-aminoadipate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17082 GO:0006615 SRP-dependent cotranslational protein targeting to membrane, docking biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006615 protein docking during SRP-dependent cotranslational protein targeting to membrane|SRP-dependent cotranslational membrane targeting, docking|SRP-dependent cotranslational protein-membrane targeting, docking The process in which an SRP-bound ribosome forms a complex with the SRP receptor in the ER membrane, allowing the ribosome to bind to the membrane, during cotranslational membrane targeting. CHEBI:17083 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17083 GO:0006612 protein targeting to membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006612 protein-membrane targeting|protein membrane targeting The process of directing proteins towards a membrane, usually using signals contained within the protein. GO:0006613 cotranslational protein targeting to membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006613 cotranslational membrane targeting|cotranslational protein membrane targeting|cotranslational protein-membrane targeting The targeting of proteins to a membrane that occurs during translation. The transport of most secretory proteins, particularly those with more than 100 amino acids, into the endoplasmic reticulum lumen occurs in this manner, as does the import of some proteins into mitochondria. CHEBI:17081 dimethylmaleate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17081 GO:0006610 ribosomal protein import into nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006610 ribosomal protein-nucleus import|ribosomal protein import into cell nucleus|ribosomal protein transport from cytoplasm to nucleus The directed movement of a ribosomal protein from the cytoplasm into the nucleus, across the nuclear membrane. At least some ribosomal proteins, including rpl12, uses the importin 11 pathway as a major route into the nucleus. GO:0006611 protein export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006611 protein-nucleus export|protein export out of nucleus|copper-induced protein export from nucleus|protein export from cell nucleus|protein transport from nucleus to cytoplasm The directed movement of a protein from the nucleus into the cytoplasm. CHEBI:32695 argininate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32695 CHEBI:32696 argininium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32696 CHEBI:32697 argininium(2+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32697 CHEBI:4429 deoxypodophyllotoxin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_4429 CHEBI:32699 argininium residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32699 CHEBI:17079 (S)-3'-hydroxy-N-methylcoclaurine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17079 CHEBI:17077 2-carboxy-D-arabinitol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17077 CHEBI:17078 L-gamma-glutamyl-L-cysteinyl-beta-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17078 GO:0006618 SRP-dependent cotranslational protein targeting to membrane, signal sequence processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006618 SRP-dependent cotranslational protein-membrane targeting, signal sequence processing|signal sequence processing during SRP-dependent cotranslational protein targeting to membrane|SRP-dependent cotranslational membrane targeting, signal sequence processing The removal of the signal peptide from a nascent protein during cotranslational membrane targeting. CHEBI:17075 6-hydroxyhexano-6-lactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17075 CHEBI:32690 D-argininium(2+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32690 CHEBI:32691 D-arginyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32691 GO:0006619 obsolete SRP-independent cotranslational protein-membrane targeting biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006619 SRP-independent cotranslational membrane targeting|SRP-independent cotranslational protein-membrane targeting|ER translocation OBSOLETE. The targeting of proteins to a membrane that occurs during translation and is independent of SRP and signal recognition. CHEBI:17076 streptomycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17076 GO:0016190 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016190 GO:0016191 synaptic vesicle uncoating biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0016191 synaptic vesicle coat depolymerization|synaptic vesicle coat protein depolymerization The removal of the protein coat on a synaptic vesicle following the pinching step at the end of budding from the presynaptic membrane. GO:0016192 vesicle-mediated transport biolink:BiologicalProcess go-plus goslim_generic|goslim_pombe|goslim_chembl|goslim_candida|goslim_pir|goslim_drosophila|goslim_aspergillus http://purl.obolibrary.org/obo/GO_0016192 vesicle transport|nonselective vesicle transport|protein sorting along secretory pathway|vesicular transport|vesicle trafficking A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane. GO:0016193 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016193 GO:0016187 obsolete synaptic vesicle internalization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016187 synaptic vesicle internalization OBSOLETE. Internalization of the contents of a synaptic vesicle into the postsynaptic membrane following endocytosis. GO:0016188 synaptic vesicle maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016188 Steps required to form an initiated synaptic vesicle into a fully formed and transmissible synaptic vesicle. GO:0016189 synaptic vesicle to endosome fusion biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0016189 Fusion of a synaptic vesicle with an endosome. GO:0016183 synaptic vesicle coating biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0016183 The formation of clathrin coated pits in the presynaptic membrane endocytic zone, triggered by the presence of high concentrations of synaptic vesicle components. This process leads to, but does not include budding of the membrane to form new vesicles. GO:0016184 obsolete synaptic vesicle retrieval biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016184 synaptic vesicle retrieval OBSOLETE. Return of a vesicle from the postsynaptic membrane to presynaptic membrane. GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0016185 synaptic vesicle budding involved in synaptic vesicle endocytosis|synaptic vesicle budding from pre-synaptic membrane Evagination of the presynaptic membrane, resulting in the formation of a new synaptic vesicle. GO:0016186 obsolete synaptic vesicle fission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016186 synaptic vesicle fission OBSOLETE. Separation of a synaptic vesicle from the presynaptic membrane. CHEBI:136061 (E)-1-(glutathione-S-yl)-omega-(methylthio)alkylhydroximate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136061 CHEBI:4249 D-tagatopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_4249 GO:0016198 axon choice point recognition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016198 The recognition of molecules at a choice point by an axon growth cone; at a choice point the growth cone determines the direction of its future growth. GO:0016199 axon midline choice point recognition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016199 The recognition of molecules at the central nervous system midline choice point by an axon growth cone; this choice point determines whether the growth cone will cross the midline. GO:0016194 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016194 GO:0016195 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016195 GO:0016196 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016196 GO:0016197 endosomal transport biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0016197 endosome transport|endosome localisation|endosome localization The directed movement of substances mediated by an endosome, a membrane-bounded organelle that carries materials enclosed in the lumen or located in the endosomal membrane. GO:0016170 interleukin-15 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016170 interleukin-15 receptor ligand|IL-15 Interacting selectively and non-covalently with the interleukin-15 receptor. GO:0016171 obsolete cell surface antigen biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016171 cell surface antigen OBSOLETE. (Was not defined before being made obsolete). GO:0016169 bacteriochlorophyll c binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016169 Interacting selectively and non-covalently with bacteriochlorophyll c, a chlorophyll of photosynthetic bacteria, for example green sulfur bacteria. GO:0016165 linoleate 13S-lipoxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016165 MetaCyc:LIPOXYGENASE-RXN|RHEA:22780|EC:1.13.11.12 carotene oxidase activity|fat oxidase activity|lipoxydase activity|lipoperoxidase activity|lipoxygenase activity|lipoxidase activity|lionoleate:O2 oxidoreductase activity|linoleate:oxygen 13-oxidoreductase activity Catalysis of the reaction: linoleate + O2 = (9Z,11E)-(13S)-13-hydroperoxyoctadeca-9,11-dienoate. GO:0016166 phytoene dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016166 Catalysis of the dehydrogenation of phytoene to produce a carotenoid intermediate such as phytofluene. GO:0016167 glial cell-derived neurotrophic factor receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016167 GDNF receptor activity|glial cell line-derived neurotrophic factor receptor activity Combining with glial cell line-derived neurotrophic factor and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0016168 chlorophyll binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016168 Interacting selectively and non-covalently with chlorophyll; any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment. GO:0016161 beta-amylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016161 MetaCyc:RXN-1827|EC:3.2.1.2|MetaCyc:RXN-12279 beta amylase activity|glycogenase activity|1,4-alpha-D-glucan maltohydrolase activity|saccharogen amylase activity Catalysis of the reaction: (1,4-alpha-D-glucosyl)(n+1) + H2O = (1,4-alpha-D-glucosyl)(n-1) + alpha-maltose. This reaction is the hydrolysis of 1,4-alpha-glucosidic linkages in polysaccharides so as to remove successive maltose units from the non-reducing ends of the chains. GO:0016162 cellulose 1,4-beta-cellobiosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016162 EC:3.2.1.91|MetaCyc:3.2.1.91-RXN exocellobiohydrolase activity|cellobiosidase activity|avicelase activity|C1 cellulase activity|cellobiohydrolase I|exo-cellobiohydrolase activity|beta-1,4-glucan cellobiohydrolase activity|1,4-beta-D-glucan cellobiohydrolase activity|exo-1,4-beta-D-glucanase activity|1,4-beta-cellobiohydrolase activity|CBH 1|exoglucanase activity|1,4-beta-glucan cellobiosidase activity|beta-1,4-glucan cellobiosylhydrolase activity|cellobiohydrolase activity|exo-beta-1,4-glucan cellobiohydrolase activity Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose and cellotetraose, releasing cellobiose from the non-reducing ends of the chains. GO:0016163 nitrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016163 UM-BBD_enzymeID:e0395|RHEA:21448|EC:1.18.6.1|MetaCyc:NITROGENASE-RXN reduced ferredoxin:dinitrogen oxidoreductase (ATP-hydrolysing) activity|iron-iron nitrogenase activity|vanadium-iron nitrogenase activity|molybdenum-iron nitrogenase activity Catalysis of the reaction: 8 reduced ferredoxin + 8 H+ + nitrogen + 16 ATP = 8 oxidized ferredoxin + 2 NH3 + 16 ADP + 16 phosphate. GO:0016164 obsolete Mo-molybdopterin oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016164 molybdopterin oxidoreductase activity|Mo-molybdopterin oxidoreductase activity OBSOLETE. (Was not defined before being made obsolete). GO:0016180 snRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016180 Any process involved in the conversion of a primary small nuclear RNA (snRNA) transcript into a mature snRNA molecule. GO:0016181 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016181 GO:0016182 synaptic vesicle budding from endosome biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0016182 endosome to synaptic vesicle budding|synaptic vesicle budding involved in synaptic vesicle exocytosis Budding of synaptic vesicles during the formation of constitutive recycling vesicles from early endosomes. GO:0031799 type 2 metabotropic glutamate receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031799 type 2 metabotropic glutamate receptor ligand Interacting selectively and non-covalently with a type 2 metabotropic glutamate receptor. GO:0031797 type 2 metabotropic GABA receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031797 type 2 metabotropic GABA receptor ligand Interacting selectively and non-covalently with a type 2 metabotropic GABA receptor. GO:0031798 type 1 metabotropic glutamate receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031798 type 1 metabotropic glutamate receptor ligand Interacting selectively and non-covalently with a type 1 metabotropic glutamate receptor. GO:0100001 regulation of skeletal muscle contraction by action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100001 Any action potential process that regulates skeletal muscle contraction. GO:0100002 negative regulation of protein kinase activity by protein phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100002 Any protein phosphorylation process that negatively regulates protein kinase activity. GO:0100003 obsolete positive regulation of sodium ion transport by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100003 OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates sodium ion transport. GO:0100004 obsolete positive regulation of peroxisome organization by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100004 OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates peroxisome organization. GO:0100005 obsolete positive regulation of ethanol catabolic process by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100005 OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates ethanol catabolic process. GO:0100006 obsolete positive regulation of sulfite transport by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100006 OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates sulfite transport. GO:0100007 obsolete negative regulation of ceramide biosynthetic process by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100007 OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates ceramide biosynthetic process. GO:0100008 regulation of fever generation by prostaglandin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100008 Any prostaglandin biosynthetic process process that regulates fever generation. GO:0100009 regulation of fever generation by prostaglandin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100009 Any prostaglandin secretion process that regulates fever generation. GO:0016176 superoxide-generating NADPH oxidase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016176 neutrophil cytosol factor 2 Increases the activity of the enzyme superoxide-generating NADPH oxidase. GO:0031795 G protein-coupled GABA receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031795 metabotropic GABA receptor binding|GABAB receptor binding|G-protein coupled GABA receptor binding|metabotropic GABA receptor ligand Interacting selectively and non-covalently with a G protein-coupled (metabotropic) GABA receptor. GO:0031796 type 1 metabotropic GABA receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031796 type 1 metabotropic GABA receptor ligand Interacting selectively and non-covalently with a type 1 metabotropic GABA receptor. GO:0016177 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016177 GO:0016178 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016178 GO:0031793 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031793 GO:0016179 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016179 GO:0031794 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031794 GO:0031791 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031791 GO:0016172 obsolete antifreeze activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016172 antifreeze activity OBSOLETE. Inhibits the formation of ice crystals in organismal fluid (e.g. blood) at below freezing exogenous temperatures. CHEBI:4222 D-pantetheine 4'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_4222 GO:0031792 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031792 GO:0016173 obsolete ice nucleation inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016173 ice nucleation inhibitor activity OBSOLETE. Inhibits the formation of ice crystals. GO:0016174 NAD(P)H oxidase H2O2-forming activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016174 Reactome:R-HSA-9698758|Reactome:R-HSA-5693681|EC:1.6.3.1 NAD(P)H:oxygen oxidoreductase activity|ThOX activity|thyroid oxidase 2 activity|thyroid NADPH oxidase activity|p138tox|NAD(P)H oxidase activity|NADPH oxidase|thyroid oxidase activity|THOX2 activity|dual oxidase activity Catalysis of the reaction: NAD(P)H + H+ + O2 = NAD(P)+ + hydrogen peroxide. GO:0016175 superoxide-generating NAD(P)H oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016175 Reactome:R-HSA-6807557|EC:1.6.3.-|Reactome:R-HSA-5668718|Reactome:R-HSA-1222376|Reactome:R-HSA-5668629|Reactome:R-HSA-1236967|Reactome:R-HSA-6789092|Reactome:R-HSA-5668731|Reactome:R-HSA-9673797|Reactome:R-HSA-1497810|Reactome:R-HSA-5218841 cytochrome B-245 Catalysis of the reaction: NAD(P)H + O2 = NAD(P)H + O2-. GO:0031790 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031790 GO:0031788 motilin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031788 motilin receptor ligand Interacting selectively and non-covalently with a motilin receptor. CHEBI:4280 (2R,4S)-2,4-diaminopentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_4280 GO:0031789 G protein-coupled acetylcholine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031789 M1 muscarinic acetylcholine receptor ligand|M2 muscarinic acetylcholine receptor ligand|M3 muscarinic acetylcholine receptor ligand|M4 muscarinic acetylcholine receptor ligand|M5 muscarinic acetylcholine receptor ligand|muscarinic acetylcholine receptor binding|M5 muscarinic acetylcholine receptor binding|M4 muscarinic acetylcholine receptor binding|M3 muscarinic acetylcholine receptor binding|M2 muscarinic acetylcholine receptor binding|M1 muscarinic acetylcholine receptor binding|G-protein coupled acetylcholine receptor binding|muscarinic acetylcholine receptor ligand Interacting selectively and non-covalently with a G protein-coupled acetylcholine receptor. GO:0031786 type 1B melatonin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031786 type 1B melatonin receptor ligand Interacting selectively and non-covalently with a type 1B melatonin receptor. GO:0031787 H9 melatonin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031787 H9 melatonin receptor ligand Interacting selectively and non-covalently with a H9 melatonin receptor. GO:0090129 positive regulation of synapse maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090129 Any process that increases the extent of synapse maturation, the process that organizes a synapse so that it attains its fully functional state. GO:0090127 positive regulation of synapse maturation by synaptic transmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090127 Any process that increases the extent of synaptic maturation as a result of the communication from a pre-synaptic cell to a post-synaptic cell across a synapse. GO:0090128 regulation of synapse maturation biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0090128 Any process that modulates the extent of synapse maturation, the process that organizes a synapse so that it attains its fully functional state. GO:0016147 obsolete protein-synthesizing GTPase activity, elongation biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016147 protein-synthesizing GTPase activity, elongation OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. CHEBI:439819 L-alpha-phenylglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_439819 GO:0016148 obsolete protein-synthesizing GTPase activity, termination biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016148 protein-synthesizing GTPase activity, termination OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. GO:0016149 translation release factor activity, codon specific biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016149 A translation release factor that is specific for one or more particular termination codons; acts at the ribosomal A-site and require polypeptidyl-tRNA at the P-site. GO:0031784 melatonin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031784 melatonin receptor ligand Interacting selectively and non-covalently with a melatonin receptor. GO:0090121 low-density lipoprotein particle disassembly involved in cholesterol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090121 The disassembly into constituent parts of the low-density lipoprotein particle in the lysosome that contributes to cholesterol transport. GO:0016143 S-glycoside metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016143 thioglycoside metabolism|S-glycoside metabolism|thioglycoside metabolic process The chemical reactions and pathways involving S-glycosides, any compound in which a glycosyl group has been substituted into a thiol group. GO:0090122 cholesterol ester hydrolysis involved in cholesterol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090122 The cholesterol metabolic process in which cholesterol esters are hydrolyzed into free fatty acids and cholesterol in the lysosome that contributes to intracellular cholesterol transport. GO:0016144 S-glycoside biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016144 S-glycoside anabolism|S-glycoside synthesis|thioglycoside biosynthetic process|S-glycoside biosynthesis|thioglycoside biosynthesis|S-glycoside formation The chemical reactions and pathways resulting in the formation of S-glycosides, any compound in which a glycosyl group has been substituted into a thiol group. GO:0031785 type 1A melatonin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031785 type 1A melatonin receptor ligand Interacting selectively and non-covalently with a type 1A melatonin receptor. GO:0016145 S-glycoside catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016145 thioglycoside catabolic process|thioglycoside catabolism|S-glycoside catabolism|S-glycoside degradation|S-glycoside breakdown The chemical reactions and pathways resulting in the breakdown of S-glycosides, any compound in which a glycosyl group has been substituted into a thiol group. GO:0031782 type 4 melanocortin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031782 type 4 melanocortin receptor ligand Interacting selectively and non-covalently with a type 4 melanocortin receptor. GO:0090120 lysosome to ER cholesterol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090120 lysosome to endoplasmic reticulum cholesterol transport The directed movement of cholesterol, cholest-5-en-3-beta-ol, or cholesterol-containing compounds, from the lysosome to the endoplasmic reticulum. GO:0016146 obsolete protein-synthesizing GTPase activity, initiation biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016146 protein-synthesizing GTPase activity, initiation OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. GO:0031783 type 5 melanocortin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031783 type 5 melanocortin receptor ligand Interacting selectively and non-covalently with a type 5 melanocortin receptor. GO:0031780 corticotropin hormone receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031780 ACTH receptor binding|corticotropin receptor binding|adrenocorticotropic hormone receptor ligand|adrenocorticotropin receptor binding|adrenocorticotropin hormone receptor binding Interacting selectively and non-covalently with a corticotropin hormone receptor. GO:0090125 cell-cell adhesion involved in synapse maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090125 trans-synaptic adhesion The attachment of the pre-synaptic cell to the post-synaptic cell via adhesion molecules that contributes to synapse maturation. GO:0090126 protein-containing complex assembly involved in synapse maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090126 protein complex assembly involved in synapse maturation The aggregation, arrangement and bonding together of a set of components to form a protein complex that contributes to synapse maturation. GO:0031781 type 3 melanocortin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031781 type 3 melanocortin receptor ligand Interacting selectively and non-covalently with a type 3 melanocortin receptor. GO:0016140 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016140 GO:0090123 lysosomal glycocalyx biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0090123 The polysaccharide-based coating on the inner side of a lysosomal membrane. It may be involved in protecting the membrane from digestion by lysosomal enzymes. GO:0016141 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016141 GO:0090124 N-4 methylation of cytosine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090124 The covalent transfer of a methyl group to N-4 of cytosine in a DNA molecule. GO:0016142 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016142 GO:0031779 melanocortin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031779 melanocortin receptor ligand Interacting selectively and non-covalently with a melanocortin receptor. GO:0016160 amylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016160 Catalysis of the hydrolysis of amylose or an amylose derivative. GO:0031777 type 1 melanin-concentrating hormone receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031777 type 1 melanin-concentrating hormone receptor ligand Interacting selectively and non-covalently with a type 1 melanin-concentrating hormone receptor. GO:0031778 type 2 melanin-concentrating hormone receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031778 type 2 melanin-concentrating hormone receptor ligand Interacting selectively and non-covalently with a type 2 melanin-concentrating hormone receptor. GO:0031775 lutropin-choriogonadotropic hormone receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031775 lutropin-choriogonadotropic hormone receptor ligand Interacting selectively and non-covalently with a lutropin-choriogonadotropic hormone receptor. GO:0031776 melanin-concentrating hormone receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031776 melanin-concentrating hormone receptor ligand Interacting selectively and non-covalently with a melanin-concentrating hormone receptor. GO:0090138 regulation of actin cytoskeleton organization by cell-cell adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090138 regulation of actin cytoskeleton organisation by cell-cell adhesion Any cell-cell adhesion process that modulates the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. GO:0090139 mitochondrial DNA packaging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090139 Any process in which mitochondrial DNA and associated proteins are formed into a compact, orderly structure. GO:0016158 3-phytase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016158 EC:3.1.3.8|MetaCyc:RXN0-1001|RHEA:16989 phytate 1-phosphatase activity|phytase activity|myo-inositol-hexaphosphate 3-phosphohydrolase activity|phytate 3-phosphatase activity|myo-inositol-hexakisphosphate 3-phosphohydrolase activity|1-phytase activity Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate. GO:0016159 muconolactone delta-isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016159 EC:5.3.3.4|MetaCyc:MUCONOLACTONE-DELTA-ISOMERASE-RXN|RHEA:12348 muconolactone isomerase activity|5-oxo-4,5-dihydrofuran-2-acetate delta3-delta2-isomerase activity|muconolactone D-isomerase activity Catalysis of the reaction: 2,5-dihydro-5-oxofuran-2-acetate = 3,4-dihydro-5-oxofuran-2-acetate. GO:0031773 kisspeptin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031773 hypogonadotropin-1 receptor binding|KiSS-1 receptor binding|hOT7T175 receptor binding|metastin receptor binding|kisspeptin receptor ligand|G-protein coupled receptor 54 binding Interacting selectively and non-covalently with a kisspeptin receptor. GO:0090132 epithelium migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090132 The process in which the population of cells that make up an epithelium undergo directed movement. GO:0016154 pyrimidine-nucleoside phosphorylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016154 EC:2.4.2.2|MetaCyc:PYRIMIDINE-NUCLEOSIDE-PHOSPHORYLASE-RXN pyrimidine-nucleoside:phosphate alpha-D-ribosyltransferase activity|Py-NPase activity Catalysis of the reaction: pyrimidine nucleoside + phosphate = pyrimidine + alpha-D-ribose 1-phosphate. GO:0031774 leukotriene receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031774 leukotriene receptor ligand Interacting selectively and non-covalently with a leukotriene receptor. GO:0016155 formyltetrahydrofolate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016155 EC:1.5.1.6|RHEA:10180|MetaCyc:FORMYLTETRAHYDROFOLATE-DEHYDROGENASE-RXN|KEGG_REACTION:R00941 10-formyltetrahydrofolate:NADP+ oxidoreductase activity|10-formyl-H2PtGlu:NADP oxidoreductase activity|10-formyl-H4folate dehydrogenase activity|N10-formyltetrahydrofolate dehydrogenase activity|10-formyl tetrahydrofolate:NADP oxidoreductase activity|10-formyltetrahydrofolate dehydrogenase activity Catalysis of the reaction: 10-formyltetrahydrofolate + H(2)O + NADP(+) = (6S)-5,6,7,8-tetrahydrofolate + CO(2) + H(+) + NADPH. GO:0090133 mesendoderm migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090133 The process in which the population of cells that make up a mesendoderm undergo directed movement. The mesendoderm is the epithelial tissue that gives rise to both mesoderm and endoderm. GO:0090130 tissue migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090130 The process in which the population of cells that make up a tissue undergo directed movement. GO:0016156 fumarate reductase (NADH) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016156 EC:1.3.1.6|RHEA:18281|MetaCyc:FUMARATE-REDUCTASE-NADH-RXN|KEGG_REACTION:R00402 NADH-fumarate reductase activity|NADH-dependent fumarate reductase activity|succinate:NAD+ oxidoreductase activity Catalysis of the reaction: NAD(+) + succinate = fumarate + H(+) + NADH. GO:0031771 type 1 hypocretin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031771 type 1 hypocretin receptor ligand|type 1 orexin receptor binding Interacting selectively and non-covalently with a type 1 hypocretin receptor. GO:0090131 mesenchyme migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090131 The process in which the population of cells that make up a mesenchyme undergo directed movement. GO:0016157 sucrose synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016157 MetaCyc:SUCROSE-SYNTHASE-RXN|EC:2.4.1.13 uridine diphosphoglucose-fructose glucosyltransferase activity|sucrose-uridine diphosphate glucosyltransferase activity|sucrose-UDP glucosyltransferase activity|UDPglucose-fructose glucosyltransferase activity|UDP-glucose-fructose glucosyltransferase activity|sucrose synthetase activity|NDP-glucose:D-fructose 2-alpha-D-glucosyltransferase activity Catalysis of the reaction: UDP-glucose + D-fructose = UDP + sucrose. GO:0031772 type 2 hypocretin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031772 type 2 hypocretin receptor ligand|type 2 orexin receptor binding Interacting selectively and non-covalently with a type 2 hypocretin receptor. GO:0016150 translation release factor activity, codon nonspecific biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016150 A translation release factor that is not specific to particular codons; binds to guanine nucleotides. GO:0090136 epithelial cell-cell adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090136 The attachment of an epithelial cell to another epithelial cell via adhesion molecules. GO:0016151 nickel cation binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016151 nickel binding Interacting selectively and non-covalently with nickel (Ni) cations. GO:0090137 epithelial cell-cell adhesion involved in epithelium migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090137 The attachment of an epithelial cell to another epithelial cell via adhesion molecules that contributes to epithelium migration. GO:0031770 growth hormone-releasing hormone receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031770 growth hormone-releasing hormone receptor ligand Interacting selectively and non-covalently with a growth hormone-releasing hormone receptor. GO:0016152 mercury (II) reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016152 EC:1.16.1.1|MetaCyc:MERCURY-II-REDUCTASE-RXN|KEGG_REACTION:R02807|UM-BBD_reactionID:r0406|RHEA:23856 mercury reductase activity|reduced NADP:mercuric ion oxidoreductase activity|mercury(II) reductase activity|mer A|mercuric reductase activity|Hg:NADP+ oxidoreductase activity|mercuric ion reductase activity|mercurate(II) reductase activity Catalysis of the reaction: H(+) + Hg + NADP(+) = Hg(2+) + NADPH. GO:0090134 cell migration involved in mesendoderm migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090134 The orderly movement of epithelial cells from one site to another that contributes to the migration of mesendodermal tissue. GO:0016153 urocanate hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016153 RHEA:13101|KEGG_REACTION:R02914|EC:4.2.1.49|MetaCyc:UROCANATE-HYDRATASE-RXN|Reactome:R-HSA-70903 3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate hydro-lyase (urocanate-forming)|imidazolonepropionate hydrolase activity|urocanase activity|3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate hydro-lyase activity Catalysis of the reaction: 4-imidazolone-5-propanoate + H(+) = trans-urocanate + H(2)O. GO:0090135 actin filament branching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090135 The formation of daughter actin filament branches at an angle on the sides of preexisting mother filaments. GO:0031768 ghrelin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031768 type 1 growth hormone secretagogue GH-releasing peptide receptor binding|ghrelin receptor ligand Interacting selectively and non-covalently with a ghrelin receptor. GO:0031769 glucagon receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031769 glucagon receptor ligand Interacting selectively and non-covalently with a glucagon receptor. GO:0031766 type 3 galanin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031766 type 3 galanin receptor ligand Interacting selectively and non-covalently with a type 3 galanin receptor. GO:0031767 gastric inhibitory polypeptide receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031767 gastric inhibitory polypeptide receptor ligand Interacting selectively and non-covalently with a gastric inhibitory polypeptide receptor. GO:0031764 type 1 galanin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031764 type 1 galanin receptor ligand Interacting selectively and non-covalently with a type 1 galanin receptor. GO:0031765 type 2 galanin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031765 type 2 galanin receptor ligand Interacting selectively and non-covalently with a type 2 galanin receptor. GO:0090107 regulation of high-density lipoprotein particle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090107 Any process that modulates the frequency, rate, or extent of high-density lipoprotein particle assembly. High-density lipoprotein particle assembly is the aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle. GO:0016129 phytosteroid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016129 phytosteroid anabolism|phytosteroid synthesis|phytosteroid formation|phytosteroid biosynthesis The chemical reactions and pathways resulting in the formation of phytosteroids, steroids that differ from animal steroids in having substitutions at C24 and/or a double bond at C22. Phytosteroids are so named because they occur in higher plants; some, notably ergosterol, are also found in fungi. GO:0090108 positive regulation of high-density lipoprotein particle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090108 Any process that increases the frequency, rate, or extent of high-density lipoprotein particle assembly. High-density lipoprotein particle assembly is the aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle. GO:0090105 pancreatic E cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090105 The process whose specific outcome is the progression of a pancreatic E cell over time, from its formation to the mature structure. GO:0090106 pancreatic E cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090106 The commitment of a cell to a pancreatic E cell fate and its capacity to differentiate into a pancreatic E cell. GO:0016125 sterol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016125 sterol metabolism The chemical reactions and pathways involving sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. GO:0016126 sterol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016126 MetaCyc:PWY-2541 sterol synthesis|sterol formation|sterol anabolism|sterol biosynthesis The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. GO:0090109 regulation of cell-substrate junction assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090109 Any process that modulates the rate, frequency, or extent of cell-substrate junction assembly. Cell-substrate junction assembly is the aggregation, arrangement and bonding together of a set of components to form a junction between a cell and its substrate. GO:0016127 sterol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016127 sterol degradation|sterol breakdown|sterol catabolism The chemical reactions and pathways resulting in the breakdown of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. GO:0016128 phytosteroid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016128 phytosteroid metabolism The chemical reactions and pathways involving phytosteroids, steroids of higher plants that differ from animal steroids in having substitutions at C24 and/or a double bond at C22. Phytosteroids are so named because they occur in higher plants; some, notably ergosterol, are also found in fungi. GO:0016121 carotene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016121 carotene catabolism|carotene degradation|carotene breakdown The chemical reactions and pathways resulting in the breakdown of carotenes, hydrocarbon carotenoids. GO:0031762 follicle-stimulating hormone receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031762 follicle stimulating hormone receptor binding|follicle stimulating hormone receptor ligand|FSH receptor binding Interacting selectively and non-covalently with a follicle-stimulating hormone receptor. CHEBI:4251 D-tagatofuranose 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_4251 GO:0016122 xanthophyll metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016122 xanthophyll metabolism The chemical reactions and pathways involving xanthophylls, oxygen-containing carotenoids. GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signalling pathway Any process that increases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand. GO:0031763 galanin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031763 galanin receptor ligand Interacting selectively and non-covalently with a galanin receptor. GO:0016123 xanthophyll biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016123 xanthophyll synthesis|xanthophyll formation|xanthophyll anabolism|xanthophyll biosynthesis The chemical reactions and pathways resulting in the formation of xanthophylls, oxygen-containing carotenoids. GO:0031760 Edg-7 lysophosphatidic acid receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031760 LPA3 receptor binding|Edg-7 lysophosphatidic acid receptor ligand Interacting selectively and non-covalently with an Edg-7 lysophosphatidic acid receptor. GO:0016124 xanthophyll catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016124 xanthophyll degradation|xanthophyll breakdown|xanthophyll catabolism The chemical reactions and pathways resulting in the breakdown of xanthophylls, oxygen-containing carotenoids. GO:0031761 fMet-Leu-Phe receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031761 fMet-Leu-Phe receptor ligand|N-formyl peptide receptor binding Interacting selectively and non-covalently with a fMet-Leu-Phe receptor. CHEBI:4250 D-tagatofuranose 1,6-bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_4250 GO:0090103 cochlea morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090103 The process in which the cochlea is generated and organized. GO:0090104 pancreatic epsilon cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090104 pancreatic E cell differentiation The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic epsilon cell. A pancreatic epsilon cell is a cell in the pancreas that secretes ghrelin. GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signalling pathway Any process that decreases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand. GO:0016120 carotene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016120 carotene anabolism|carotene synthesis|carotene formation|carotene biosynthesis The chemical reactions and pathways resulting in the formation of carotenes, hydrocarbon carotenoids. GO:0090102 cochlea development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090102 The progression of the cochlea over time from its formation to the mature structure. The cochlea is the snail-shaped portion of the inner ear that is responsible for the detection of sound. GO:0031759 Edg-6 sphingosine 1-phosphate receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031759 Edg-6 sphingosine 1-phosphate receptor ligand Interacting selectively and non-covalently with an Edg-6 sphingosine 1-phosphate receptor. GO:0031757 Edg-4 lysophosphatidic acid receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031757 Edg-4 lysophosphatidic acid receptor ligand|LPA2 receptor binding Interacting selectively and non-covalently with an Edg-4 lysophosphatidic acid receptor. GO:0031758 Edg-5 sphingosine 1-phosphate receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031758 Edg-5 sphingosine 1-phosphate receptor ligand Interacting selectively and non-covalently with an Edg-5 sphingosine 1-phosphate receptor. GO:0031755 Edg-2 lysophosphatidic acid receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031755 Edg-2 lysophosphatidic acid receptor ligand|LPA1 receptor binding Interacting selectively and non-covalently with an Edg-2 lysophosphatidic acid receptor. GO:0031756 Edg-3 sphingosine 1-phosphate receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031756 Edg-3 sphingosine 1-phosphate receptor ligand Interacting selectively and non-covalently with an Edg-3 sphingosine 1-phosphate receptor. GO:0031753 endothelial differentiation G protein-coupled receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031753 endothelial differentiation G-protein coupled receptor ligand|endothelial differentiation G-protein coupled receptor binding Interacting selectively and non-covalently with an endothelial differentiation G protein-coupled receptor. GO:0031754 Edg-1 sphingosine 1-phosphate receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031754 Edg-1 sphingosine 1-phosphate receptor ligand Interacting selectively and non-covalently with an Edg-1 sphingosine 1-phosphate receptor. GO:0090118 receptor-mediated endocytosis involved in cholesterol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090118 receptor-mediated endocytosis involved in intracellular cholesterol transport|receptor-mediated endocytosis of LDL|receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport A receptor-mediated endocytosis process involved in intracellular cholesterol transport. GO:0090119 vesicle-mediated cholesterol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090119 The directed movement of cholesterol, cholest-5-en-3-beta-ol, or cholesterol-containing compounds, by membrane-bounded vesicles. GO:0090116 C-5 methylation of cytosine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090116 The covalent transfer of a methyl group to C-5 of cytosine in a DNA molecule. GO:0090117 endosome to lysosome transport of low-density lipoprotein particle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090117 endosome to lysosome transport of LDL The directed movement of low-density lipoprotein particle from endosomes to lysosomes. GO:0016136 saponin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016136 saponin degradation|saponin catabolism|saponin breakdown The chemical reactions and pathways resulting in the breakdown of saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection. GO:0016137 glycoside metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016137 O-glycoside metabolic process|glycoside metabolism|O-glycoside metabolism The chemical reactions and pathways involving glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound. GO:0016138 glycoside biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016138 glycoside anabolism|O-glycoside synthesis|glycoside synthesis|O-glycoside formation|glycoside formation|glycoside biosynthesis|O-glycoside biosynthetic process|O-glycoside biosynthesis|O-glycoside anabolism The chemical reactions and pathways resulting in the formation of glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound. GO:0016139 glycoside catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016139 O-glycoside degradation|glycoside degradation|O-glycoside breakdown|glycoside catabolism|glycoside breakdown|O-glycoside catabolism|O-glycoside catabolic process The chemical reactions and pathways resulting in the breakdown of glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound. GO:0090110 COPII-coated vesicle cargo loading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090110 COPII coat-cargo complex assembly|cargo selection into COPII-coated vesicle|cargo loading into COPII-coated vesicle|cargo loading into COPII vesicle The formation of a macromolecular complex between the COPII coat proteins and proteins and/or lipoproteins that are going to be transported by the COPII vesicle to the Golgi. GO:0031751 D4 dopamine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031751 D4 dopamine receptor ligand Interacting selectively and non-covalently with a D4 dopamine receptor. GO:0016132 brassinosteroid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016132 MetaCyc:PWY-2582|MetaCyc:PWY-699 brassinosteroid biosynthesis|brassinosteroid anabolism|brassinosteroid synthesis|brassinosteroid formation The chemical reactions and pathways resulting in the formation of brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects. GO:0016133 brassinosteroid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016133 brassinosteroid catabolism|brassinosteroid degradation|brassinosteroid breakdown The chemical reactions and pathways resulting in the breakdown of brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects. GO:0031752 D5 dopamine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031752 D1B dopamine receptor binding|D5 dopamine receptor ligand Interacting selectively and non-covalently with a D5 dopamine receptor. GO:0090111 regulation of COPII vesicle uncoating biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090111 Any process that modulates the frequency, rate or extent of COPII vesicle uncoating, the process in which COPII vesicle coat proteins are disassembled, and released. GO:0016134 saponin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016134 saponin metabolism The chemical reactions and pathways involving saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection. GO:0031750 D3 dopamine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031750 D3 dopamine receptor ligand Interacting selectively and non-covalently with a D3 dopamine receptor. GO:0016135 saponin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016135 saponin biosynthesis|saponin anabolism|saponin synthesis|saponin formation The chemical reactions and pathways resulting in the formation of saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection. GO:0090114 COPII-coated vesicle budding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090114 ER vesicle budding|COPII vesicle budding|ER exit The evagination of an endoplasmic reticulum membrane, resulting in formation of a COPII-coated vesicle. GO:0090115 obsolete C-5 methylation on cytosine involved in chromatin silencing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090115 OBSOLETE. The covalent transfer of a methyl group to C-5 of cytosine in a DNA molecule that contributes to chromatin silencing. GO:0016130 phytosteroid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016130 phytosteroid degradation|phytosteroid breakdown|phytosteroid catabolism The chemical reactions and pathways resulting in the breakdown of phytosteroids, steroids that differ from animal steroids in having substitutions at C24 and/or a double bond at C22. Phytosteroids are so named because they occur in higher plants; some, notably ergosterol, are also found in fungi. GO:0090112 COPII vesicle uncoating biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090112 The process in which COPII vesicle coat proteins are disassembled, and released. GO:0016131 brassinosteroid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016131 brassinosteroid metabolism The chemical reactions and pathways involving brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects. GO:0090113 regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090113 The GTP hydrolysis process that modulates the rate, frequency, or extent of ER to Golgi vesicle-mediated transport, the directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. GO:0100050 obsolete negative regulation of mating type switching by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100050 OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates mating type switching. GO:0100051 obsolete positive regulation of meiotic nuclear division by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100051 OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates meiotic nuclear division. GO:0100052 obsolete negative regulation of G1/S transition of mitotic cell cycle by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100052 OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates G1/S transition of mitotic cell cycle. GO:0100053 obsolete positive regulation of sulfate assimilation by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100053 OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates sulfate assimilation. CHEBI:81559 resolvin E1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_81559 GO:0100054 obsolete positive regulation of flocculation via cell wall protein-carbohydrate interaction by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100054 OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates flocculation via cell wall protein-carbohydrate interaction. GO:0100055 obsolete positive regulation of phosphatidylserine biosynthetic process by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100055 OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates phosphatidylserine biosynthetic process. GO:0100056 obsolete negative regulation of phosphatidylserine biosynthetic process by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100056 OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates phosphatidylserine biosynthetic process. GO:0100057 obsolete regulation of phenotypic switching by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100057 OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates phenotypic switching. GO:0100058 obsolete positive regulation of phenotypic switching by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100058 OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates phenotypic switching. GO:0100059 obsolete negative regulation of phenotypic switching by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100059 OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates phenotypic switching. CHEBI:81551 bacteriochlorophyllide d biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_81551 CHEBI:81552 bacteriochlorophyllide c biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_81552 GO:0100060 obsolete negative regulation of SREBP signaling pathway by DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0100060 OBSOLETE. Any DNA binding that negatively regulates SREBP signaling pathway. GO:0100061 obsolete negative regulation of SREBP signaling pathway by transcription factor catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100061 OBSOLETE. Any transcription factor catabolic process process that negatively regulates SREBP signaling pathway. GO:0100062 obsolete positive regulation of SREBP signaling pathway by transcription factor catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100062 OBSOLETE. Any transcription factor catabolic process process that positively_regulates SREBP signaling pathway. GO:0100063 obsolete regulation of dipeptide transmembrane transport by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100063 OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates dipeptide transmembrane transport. GO:0100064 obsolete negative regulation of filamentous growth of a population of unicellular organisms in response to starvation by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100064 OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates filamentous growth of a population of unicellular organisms in response to starvation. GO:0100065 obsolete negative regulation of leucine import by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100065 OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates leucine import. GO:0100066 obsolete negative regulation of induction of conjugation with cellular fusion by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100066 OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates induction of conjugation with cellular fusion. GO:0100067 positive regulation of spinal cord association neuron differentiation by canonical Wnt signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100067 Any canonical Wnt signaling pathway process that positively_regulates spinal cord association neuron differentiation. GO:0100068 obsolete positive regulation of pyrimidine-containing compound salvage by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100068 OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates pyrimidine-containing compound salvage. GO:0100069 obsolete negative regulation of neuron apoptotic process by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100069 OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates neuron apoptotic process. CHEBI:81567 thyroid stimulating hormone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_81567 CHEBI:81564 resolvin D1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_81564 CHEBI:81565 resolvin D2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_81565 CHEBI:81562 5S-Hydroperoxy-18R-HEPE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_81562 CHEBI:81563 18(R)-HEPE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_81563 GO:0100070 obsolete obsolete regulation of fatty acid biosynthetic process by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100070 OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates fatty acid biosynthetic process. NCBITaxon:207245 Fornicata organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_207245 Diplomonadida group PATO-PROPERTY:has_cross_section has_cross_section biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/pato#has_cross_section has_cross_section s3 has_cross_section s3 if and only if : there exists some 2d plane that intersects the bearer of s3, and the impression of s3 upon that plane has shape quality s2. GO:0100010 positive regulation of fever generation by prostaglandin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100010 Any prostaglandin biosynthetic process process that positively_regulates fever generation. GO:0100011 positive regulation of fever generation by prostaglandin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100011 Any prostaglandin secretion process that positively_regulates fever generation. GO:0100012 regulation of heart induction by canonical Wnt signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100012 Any canonical Wnt signaling pathway process that regulates heart induction. GO:0100013 obsolete positive regulation of fatty acid beta-oxidation by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100013 OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates fatty acid beta-oxidation. GO:0100014 obsolete positive regulation of mating type switching by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100014 OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates mating type switching. GO:0100015 obsolete positive regulation of inositol biosynthetic process by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100015 OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates inositol biosynthetic process. GO:0100016 obsolete regulation of thiamine biosynthetic process by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100016 OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates thiamine biosynthetic process. GO:0100017 obsolete negative regulation of cell-cell adhesion by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100017 OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates single organismal cell-cell adhesion. GO:0100018 obsolete regulation of glucose import by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100018 OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates glucose import. GO:0100019 obsolete regulation of cAMP-mediated signaling by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100019 OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates cAMP-mediated signaling. GO:0100020 obsolete regulation of transport by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100020 OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates transport. GO:0100021 obsolete regulation of iron ion transport by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100021 regulation of iron ion import by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates iron ion transport. GO:0100022 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0100022 GO:0100023 obsolete regulation of meiotic nuclear division by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100023 OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates meiotic nuclear division. GO:0100024 obsolete regulation of carbohydrate metabolic process by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100024 OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates carbohydrate metabolic process. GO:0100025 obsolete negative regulation of cellular amino acid biosynthetic process by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100025 OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates cellular amino acid biosynthetic process. GO:0100026 positive regulation of DNA repair by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100026 Any transcription from RNA polymerase II promoter process that positively regulates DNA repair. GO:0100027 obsolete regulation of cell separation after cytokinesis by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100027 OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates cell separation after cytokinesis. GO:0100028 obsolete regulation of conjugation with cellular fusion by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100028 OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates conjugation with cellular fusion. GO:0100029 obsolete regulation of histone modification by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100029 OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates histone modification. GO:0100030 obsolete regulation of histone acetylation by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100030 OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates histone acetylation. GO:0100031 obsolete regulation of histone methylation by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100031 OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates histone methylation. GO:0100032 obsolete positive regulation of phospholipid biosynthetic process by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100032 OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates phospholipid biosynthetic process. GO:0100033 obsolete regulation of fungal-type cell wall biogenesis by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100033 OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates fungal-type cell wall biogenesis. GO:0100034 obsolete regulation of 4,6-pyruvylated galactose residue biosynthetic process by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100034 OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates 4,6-pyruvylated galactose residue biosynthetic process. GO:0100035 obsolete negative regulation of transmembrane transport by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100035 OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates transmembrane transport. GO:0100036 obsolete positive regulation of purine nucleotide biosynthetic process by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100036 OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates purine nucleotide biosynthetic process. GO:0100037 obsolete positive regulation of cellular alcohol catabolic process by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100037 OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates cellular alcohol catabolic process. GO:0100038 obsolete regulation of cellular response to oxidative stress by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100038 OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates cellular response to oxidative stress. GO:0100039 obsolete regulation of pyrimidine nucleotide biosynthetic process by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100039 OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates pyrimidine nucleotide biosynthetic process. CHEBI:136065 1-aci-nitro-omega-(methylsulfanyl)alkane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136065 CHEBI:136067 3-aci-nitropropanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136067 GO:0100040 obsolete negative regulation of invasive growth in response to glucose limitation by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100040 OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates invasive growth in response to glucose limitation. GO:0100041 obsolete positive regulation of pseudohyphal growth by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100041 OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates pseudohyphal growth. GO:0100042 obsolete negative regulation of pseudohyphal growth by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100042 OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates pseudohyphal growth. GO:0100043 obsolete negative regulation of cellular response to alkaline pH by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100043 OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates cellular response to alkaline pH. GO:0100044 obsolete negative regulation of cellular hyperosmotic salinity response by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100044 OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates cellular hyperosmotic salinity response. GO:0100045 negative regulation of arginine catabolic process by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100045 Any transcription from RNA polymerase II promoter process that negatively regulates arginine catabolic process. GO:0100046 obsolete positive regulation of arginine biosynthetic process by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100046 OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates arginine biosynthetic process. GO:0100047 obsolete negative regulation of inositol biosynthetic process by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100047 OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates inositol biosynthetic process. GO:0100048 obsolete positive regulation of phosphatidylcholine biosynthetic process by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100048 OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates phosphatidylcholine biosynthetic process. GO:0100049 obsolete negative regulation of phosphatidylcholine biosynthetic process by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0100049 OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates phosphatidylcholine biosynthetic process. CHEBI:136078 4-O-[di(2R)-1-glycerylphosphono]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl undecaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136078 GO:0006704 glucocorticoid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006704 glucocorticoid anabolism|glucocorticoid synthesis|glucocorticoid formation|glucocorticoid biosynthesis The chemical reactions and pathways resulting in the formation of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. GO:0006705 mineralocorticoid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006705 mineralocorticoid anabolism|mineralocorticoid synthesis|mineralocorticoid biosynthesis|mineralocorticoid formation The chemical reactions and pathways resulting in the formation of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. GO:0006702 androgen biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006702 androgen anabolism|androgen biosynthesis|androgen synthesis|androgen formation The chemical reactions and pathways resulting in the formation of androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics. GO:0006703 estrogen biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006703 estrogen formation|oestrogen biosynthesis|oestrogen biosynthetic process|estrogen anabolism|estrogen synthesis|estrogen biosynthesis The chemical reactions and pathways resulting in the formation of estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants. GO:0006700 C21-steroid hormone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006700 C21-steroid hormone biosynthesis|C21-steroid hormone anabolism|C21-steroid hormone synthesis|C21-steroid hormone formation The chemical reactions and pathways resulting in the formation of C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones. GO:0006701 progesterone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006701 progesterone anabolism|progesterone synthesis|progesterone biosynthesis|progesterone formation The chemical reactions and pathways resulting in the formation of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants. CHEBI:32549 epsilon-carotene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32549 UBERON:0007778 umbilical artery endothelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007778 An endothelium that is part of a umbilical artery. UBERON:0007779 transudate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007779 plasma ultrafiltrate Any bodily fluid that has passed through a membrane such as the capillary wall, as a result of unbalanced hydrostatic and osmotic forces CHEBI:32544 nicotinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32544 GO:0006708 ecdysone catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006708 ecdysone degradation|ecdysone catabolism|ecdysone breakdown The chemical reactions and pathways resulting in the breakdown of ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects. UBERON:0007771 epidermis gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007771 epidermal gland|gland of epidermis A gland that is part of a epidermis. GO:0006709 progesterone catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006709 progesterone degradation|progesterone breakdown|progesterone catabolism The chemical reactions and pathways resulting in the breakdown of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants. GO:0006706 steroid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006706 steroid breakdown|steroid catabolism|steroid degradation The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. GO:0006707 cholesterol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006707 cholesterol degradation|cholesterol breakdown|cholesterol catabolism The chemical reactions and pathways resulting in the breakdown of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. GO:0006715 farnesol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006715 farnesol biosynthesis|farnesol anabolism|farnesol synthesis|farnesol formation The chemical reactions and pathways resulting in the formation of the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol. GO:0006716 juvenile hormone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006716 juvenile hormone metabolism The chemical reactions and pathways involving juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis. GO:0006713 glucocorticoid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006713 glucocorticoid degradation|glucocorticoid catabolism|glucocorticoid breakdown The chemical reactions and pathways resulting in the breakdown of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. GO:0006714 sesquiterpenoid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006714 sesquiterpenoid metabolism The chemical reactions and pathways involving sesquiterpenoid compounds, terpenoids with three isoprene units. GO:0006711 estrogen catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006711 estrogen catabolism|oestrogen catabolic process|estrogen degradation|oestrogen catabolism|estrogen breakdown The chemical reactions and pathways resulting in the breakdown of estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants. GO:0006712 mineralocorticoid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006712 mineralocorticoid degradation|mineralocorticoid breakdown|mineralocorticoid catabolism The chemical reactions and pathways resulting in the breakdown of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. GO:0006710 androgen catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006710 androgen degradation|androgen breakdown|androgen catabolism The chemical reactions and pathways resulting in the breakdown of androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics. CHEBI:32557 D-lysinium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32557 CHEBI:32558 D-lysinium(2+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32558 CHEBI:32559 D-lysyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32559 CHEBI:32550 L-lysinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32550 CHEBI:32551 L-lysinium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32551 CHEBI:32552 L-lysinium(2+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32552 CHEBI:32553 L-lysyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32553 CHEBI:32556 D-lysinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32556 GO:0006719 juvenile hormone catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006719 juvenile hormone catabolism|juvenile hormone degradation|juvenile hormone breakdown The chemical reactions and pathways resulting in the breakdown of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis. GO:0006717 obsolete juvenile hormone binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006717 juvenile hormone binding OBSOLETE. (Was not defined before being made obsolete). GO:0006718 juvenile hormone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006718 juvenile hormone anabolism|juvenile hormone synthesis|juvenile hormone formation|juvenile hormone biosynthesis The chemical reactions and pathways resulting in the formation of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis. CHEBI:32524 D-histidinate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32524 CHEBI:32526 D-histidinium(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32526 CHEBI:32527 D-histidinium(2+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32527 CHEBI:32529 histidinate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32529 CHEBI:32523 D-histidinate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32523 CHEBI:32535 histidine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32535 CHEBI:32536 histidinium residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32536 CHEBI:533015 3,3',5-triiodo-L-thyronine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_533015 CHEBI:32538 bacillosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32538 CHEBI:32539 daunosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32539 CHEBI:32530 histidinate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32530 CHEBI:32531 histidinium(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32531 CHEBI:32532 histidinium(2+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32532 CHEBI:32504 phenylalaninate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32504 CHEBI:32505 phenylalaninium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32505 CHEBI:32507 glycinium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32507 CHEBI:32508 glycinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32508 CHEBI:32513 L-histidinium(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32513 CHEBI:32510 L-histidinate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32510 CHEBI:32511 L-histidinate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32511 CHEBI:32512 L-histidinium(2+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32512 UBERON:0007798 vascular system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007798 Gefaesssystem@de Anatomical system that consists of all blood and lymph vessels. UBERON:0007794 secretion of serous gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007794 serosal fluid|serous fluid|serous gland fluid Any fluid produced by a serous gland. CHEBI:81548 3-vinylbacteriochlorophyllide d biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_81548 CHEBI:81546 bacteriochlorophyllide a biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_81546 CHEBI:81544 3-(1-hydroxyethyl)bacteriochlorophyllide a biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_81544 CHEBI:81545 3-(1-hydroxyethyl)chlorophyllide a biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_81545 GO:0031748 D1 dopamine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031748 D1 dopamine receptor ligand|D1A dopamine receptor binding Interacting selectively and non-covalently with a D1 dopamine receptor. GO:0031749 D2 dopamine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031749 D2 dopamine receptor ligand Interacting selectively and non-covalently with a D2 dopamine receptor. GO:0031746 type 1 cysteinyl leukotriene receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031746 type 1 cysteinyl leukotriene receptor ligand Interacting selectively and non-covalently with a type 1 cysteinyl leukotriene receptor. GO:0031747 type 2 cysteinyl leukotriene receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031747 type 2 cysteinyl leukotriene receptor ligand Interacting selectively and non-covalently with a type 2 cysteinyl leukotriene receptor. GO:0006788 heme oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006788 haem oxidation The chemical reactions and pathways resulting in the loss of electrons from one or more atoms in heme. GO:0090040 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090040 GO:0031744 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031744 GO:0006789 bilirubin conjugation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006789 The chemical reactions and pathways resulting in the formation of bilirubin monoglucuronide or bilirubin diglucuronide, water-soluble derivatives of bilirubin. GO:0090041 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090041 GO:0031745 cysteinyl leukotriene receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031745 cysteinyl leukotriene receptor ligand Interacting selectively and non-covalently with a cysteinyl leukotriene receptor. GO:0006786 heme C biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006786 heme C anabolism|heme C synthesis|heme C formation|haem C biosynthetic process|haem C biosynthesis|heme C biosynthesis The chemical reactions and pathways resulting in the formation of heme c, a derivative of heme found in cytochromes c, b4, and f. GO:0031742 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031742 GO:0006787 porphyrin-containing compound catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006787 porphyrin degradation|porphyrin breakdown|porphyrin catabolism|porphyrin catabolic process The chemical reactions and pathways resulting in the breakdown of any member of a large group of derivatives or analogs of porphyrin. Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group. GO:0031743 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031743 GO:0006784 heme A biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006784 heme A anabolism|haem A biosynthesis|heme A synthesis|haem A biosynthetic process|heme A formation|heme A biosynthesis The chemical reactions and pathways resulting in the formation of heme A, a derivative of heme found in cytochrome aa3. GO:0006785 heme B biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006785 protoheme biosynthesis|protoheme biosynthetic process|heme B anabolism|heme B synthesis|haem B biosynthesis|haem B biosynthetic process|heme B formation|heme B biosynthesis The chemical reactions and pathways resulting in the formation of heme B, a Fe(II) porphyrin complex readily isolated from the hemoglobin of beef blood, but also found in other proteins including other hemoglobins, myoglobins, cytochromes P-450, catalases, peroxidases as well as b type cytochromes. GO:0006782 protoporphyrinogen IX biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006782 protoporphyrinogen IX anabolism|protoporphyrinogen IX synthesis|protoporphyrinogen IX biosynthesis|protoporphyrinogen IX formation The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX. GO:0006783 heme biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006783 MetaCyc:HEMESYN2-PWY heme anabolism|haem biosynthesis|haem biosynthetic process|heme synthesis|heme formation|heme biosynthesis The chemical reactions and pathways resulting in the formation of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, from less complex precursors. GO:0006780 uroporphyrinogen III biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006780 uroporphyrinogen III biosynthesis|uroporphyrinogen III anabolism|uroporphyrinogen III synthesis|uroporphyrinogen III formation The chemical reactions and pathways resulting in the formation of uroporphyrinogen III. GO:0006781 succinyl-CoA pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006781 biosynthetic process of protoporphyrin IX via succinyl CoA|biosynthesis of protoporphyrin IX via succinyl CoA|biosynthetic process of protoporphyrin IX via succinyl-CoA|biosynthesis of protoporphyrin IX via succinyl-CoA|succinyl CoA pathway The chemical reactions that utilize succinyl-CoA in the synthesis of protoporphyrin IX. GO:0016107 sesquiterpenoid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016107 sesquiterpenoid catabolism|sesquiterpenoid degradation|sesquiterpenoid breakdown The chemical reactions and pathways resulting in the breakdown of sesquiterpenoid compounds, terpenoids with three isoprene units. GO:0016108 tetraterpenoid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016108 tetraterpene metabolic process|tetraterpene metabolism|tetraterpenoid metabolism The chemical reactions and pathways involving tetraterpenoid compounds, terpenoids with eight isoprene units. GO:0016109 tetraterpenoid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016109 tetraterpenoid anabolism|tetraterpene biosynthesis|tetraterpene biosynthetic process|tetraterpenoid synthesis|tetraterpenoid formation|tetraterpenoid biosynthesis The chemical reactions and pathways resulting in the formation of tetraterpenoid compounds, terpenoids with eight isoprene units. GO:0016103 diterpenoid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016103 diterpenoid catabolism|diterpenoid degradation|diterpenoid breakdown|diterpene catabolism|diterpene catabolic process The chemical reactions and pathways resulting in the breakdown of diterpenoid compounds, terpenoids with four isoprene units. GO:0016104 triterpenoid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016104 triterpenoid anabolism|triterpenoid synthesis|triterpenoid formation|triterpene biosynthetic process|triterpene biosynthesis|triterpenoid biosynthesis The chemical reactions and pathways resulting in the formation of triterpenoid compounds, terpenoids with six isoprene units. GO:0016105 triterpenoid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016105 triterpene catabolism|triterpenoid degradation|triterpenoid catabolism|triterpenoid breakdown|triterpene catabolic process The chemical reactions and pathways resulting in the breakdown of triterpenoid compounds, terpenoids with six isoprene units. GO:0016106 sesquiterpenoid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016106 sesquiterpenoid synthesis|sesquiterpenoid formation|sesquiterpenoid biosynthesis|sesquiterpenoid anabolism The chemical reactions and pathways resulting in the formation of sesquiterpenoid compounds, terpenoids with three isoprene units. GO:0090044 positive regulation of tubulin deacetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090044 Any process that increases the frequency, rate or extent of tubulin deacetylation. Tubulin deacetylation is the removal of an acetyl group from a protein amino acid. GO:0031740 type A cholecystokinin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031740 type A cholecystokinin receptor ligand Interacting selectively and non-covalently with a type A cholecystokinin receptor. GO:0016100 monoterpenoid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016100 monoterpenoid catabolism|monoterpenoid degradation|monoterpenoid breakdown The chemical reactions and pathways resulting in the breakdown of monoterpenoid compounds, terpenoids having a C10 skeleton. GO:0090045 positive regulation of deacetylase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090045 Any process that activates or increases the frequency, rate or extent of deacetylase activity, the catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule. GO:0031741 type B gastrin/cholecystokinin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031741 type B gastrin/cholecystokinin receptor ligand Interacting selectively and non-covalently with a type B gastrin/cholecystokinin receptor. GO:0016101 diterpenoid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016101 diterpenoid metabolism|diterpene metabolic process|diterpene metabolism The chemical reactions and pathways involving diterpenoid compounds, terpenoids with four isoprene units. GO:0090042 tubulin deacetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090042 The removal of an acetyl group from tubulin. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid. GO:0016102 diterpenoid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016102 diterpenoid synthesis|diterpenoid biosynthesis|diterpenoid formation|diterpene biosynthetic process|diterpene biosynthesis|diterpenoid anabolism The chemical reactions and pathways resulting in the formation of diterpenoid compounds, terpenoids with four isoprene units. GO:0090043 regulation of tubulin deacetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090043 Any process that modulates the frequency, rate or extent of tubulin deacetylation. Tubulin deacetylation is the removal of an acetyl group from a protein amino acid. GO:0090048 obsolete negative regulation of transcription regulator activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090048 negative regulation of transcription regulator activity OBSOLETE. Any process that decreases the frequency, rate or extent of transcription regulator activity, any molecular function that plays a role in regulating transcription; may bind a promoter or enhancer DNA sequence or interact with a DNA-binding transcription factor. GO:0090049 regulation of cell migration involved in sprouting angiogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090049 Any process that modulates the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis. GO:0090046 obsolete regulation of transcription regulator activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090046 regulation of transcription regulator activity OBSOLETE. Any process that modulates the frequency, rate or extent of transcription regulator activity, any molecular function that plays a role in regulating transcription; may bind a promoter or enhancer DNA sequence or interact with a DNA-binding transcription factor. GO:0090047 obsolete positive regulation of transcription regulator activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090047 positive regulation of transcription regulator activity OBSOLETE. Any process that increases the frequency, rate or extent of transcription regulator activity, any molecular function that plays a role in regulating transcription; may bind a promoter or enhancer DNA sequence or interact with a DNA-binding transcription factor. GO:0031737 CX3C chemokine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031737 fractalkine receptor binding|CX3C chemokine receptor ligand Interacting selectively and non-covalently with a CX3C chemokine receptor. GO:0031738 XCR1 chemokine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031738 lymphotactin receptor binding|XCR1 chemokine receptor ligand Interacting selectively and non-covalently with a XCR1 chemokine receptor. GO:0031735 CCR10 chemokine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031735 CCR10 chemokine receptor ligand Interacting selectively and non-covalently with a CCR10 chemokine receptor. GO:0031736 CCR11 chemokine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031736 CCR11 chemokine receptor ligand Interacting selectively and non-covalently with a CCR11 chemokine receptor. GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090051 Any process that decreases the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis. GO:0006799 polyphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006799 polyphosphate biosynthesis|polyphosphate anabolism|polyphosphate synthesis|polyphosphate formation The chemical reactions and pathways resulting in the formation of a polyphosphate, the anion or salt of polyphosphoric acid. GO:0031733 CCR8 chemokine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031733 CCR8 chemokine receptor ligand Interacting selectively and non-covalently with a CCR8 chemokine receptor. GO:0090052 regulation of pericentric heterochromatin assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090052 regulation of chromatin silencing at centromere Any process that modulates the frequency, rate or extent of chromatin silencing at the centromere. Chromatin silencing at the centromere is the repression of transcription of centromeric DNA by altering the structure of chromatin. GO:0031734 CCR9 chemokine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031734 CCR9 chemokine receptor ligand Interacting selectively and non-covalently with a CCR9 chemokine receptor. GO:0031731 CCR6 chemokine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031731 LARC receptor binding|CCR6 chemokine receptor ligand Interacting selectively and non-covalently with a CCR6 chemokine receptor. GO:0006797 polyphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006797 polyphosphate metabolism The chemical reactions and pathways involving a polyphosphate, the anion or salt of polyphosphoric acid. GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090050 Any process that increases the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis. GO:0031732 CCR7 chemokine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031732 MIP-3 beta receptor binding|type 1 EBV-induced G-protein coupled receptor binding|CCR7 chemokine receptor ligand Interacting selectively and non-covalently with a CCR7 chemokine receptor. GO:0006798 polyphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006798 polyphosphate catabolism|polyphosphate degradation|polyphosphate breakdown The chemical reactions and pathways resulting in the breakdown of a polyphosphate, the anion or salt of polyphosphoric acid. GO:0006795 regulation of phosphorus utilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006795 Any process that modulates the frequency, rate or extent of phosphorus utilization. GO:0006796 phosphate-containing compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006796 phosphate metabolic process|phosphate metabolism The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid. GO:0006793 phosphorus metabolic process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0006793 phosphorus metabolism The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4). GO:0006794 phosphorus utilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006794 A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary phosphorus source and then activates genes to scavenge the last traces of the primary phosphorus source and to transport and metabolize alternative phosphorus sources. The utilization process begins when the cell or organism detects phosphorus levels, includes the phosphorus-containing substances, and ends when phosphorus is incorporated into the cell or organism's metabolism. GO:0006791 sulfur utilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006791 sulphur utilization A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary sulfur sources and then activates genes to scavenge the last traces of the primary sulfur source and to transport and metabolize alternate sulfur sources. The utilization process begins when the cell or organism detects sulfur levels, includes the activation of genes whose products detect, transport or metabolize sulfur-containing compounds, and ends when the sulfur is incorporated into the cell or organism's metabolism. GO:0006792 regulation of sulfur utilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006792 regulation of sulphur utilization Any process that modulates the frequency, rate or extent of sulfur utilization. GO:0031739 cholecystokinin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031739 cholecystokinin receptor ligand Interacting selectively and non-covalently with a cholecystokinin receptor. GO:0006790 sulfur compound metabolic process biolink:BiologicalProcess go-plus goslim_pombe|goslim_chembl|goslim_pir|goslim_drosophila|goslim_generic http://purl.obolibrary.org/obo/GO_0006790 Wikipedia:Sulfur_metabolism sulfur metabolism|sulphur metabolism|sulphur metabolic process The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione. GO:0016118 carotenoid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016118 carotenoid degradation|carotenoid breakdown|carotenoid catabolism The chemical reactions and pathways resulting in the breakdown of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail. GO:0016119 carotene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016119 carotene metabolism The chemical reactions and pathways involving carotenes, hydrocarbon carotenoids. CHEBI:112106 (R)-3-(indol-3-yl)-2-oxobutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_112106 GO:0016114 terpenoid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016114 Wikipedia:Terpenoid terpenoid anabolism|terpenoid synthesis|terpenoid formation|terpenoid biosynthesis The chemical reactions and pathways resulting in the formation of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure. GO:0016115 terpenoid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016115 terpenoid catabolism|terpenoid degradation|terpenoid breakdown The chemical reactions and pathways resulting in the breakdown of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure. GO:0016116 carotenoid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016116 carotenoid metabolism The chemical reactions and pathways involving carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail. GO:0016117 carotenoid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016117 MetaCyc:CAROTENOID-PWY carotenoid biosynthesis|carotenoid anabolism|carotenoid synthesis|carotenoid formation The chemical reactions and pathways resulting in the formation of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail. GO:0016110 tetraterpenoid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016110 tetraterpenoid catabolism|tetraterpenoid degradation|tetraterpenoid breakdown|tetraterpene catabolic process|tetraterpene catabolism The chemical reactions and pathways resulting in the breakdown of tetraterpenoid compounds, terpenoids with eight isoprene units. GO:0090055 positive regulation of silent mating-type cassette heterochromatin assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090055 positive regulation of chromatin silencing at silent mating-type cassette Any process that increases the frequency, rate, or extent of chromatin silencing at silent mating-type cassette. Chromatin silencing at silent mating-type cassette is the repression of transcription at silent mating-type loci by altering the structure of chromatin. GO:0016111 polyterpenoid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016111 polyterpene metabolism|polyterpene metabolic process|polyterpenoid metabolism The chemical reactions and pathways involving polyterpenoid compounds, terpenoids with more than eight isoprene units. GO:0031730 CCR5 chemokine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031730 CCR5 chemokine receptor ligand Interacting selectively and non-covalently with a CCR5 chemokine receptor. GO:0090056 regulation of chlorophyll metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090056 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chlorophyll. GO:0016112 polyterpenoid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016112 polyterpene biosynthetic process|polyterpene biosynthesis|polyterpenoid biosynthesis|polyterpenoid anabolism|polyterpenoid synthesis|polyterpenoid formation The chemical reactions and pathways resulting in the formation of polyterpenoid compounds, terpenoids with more than eight isoprene units. GO:0090053 positive regulation of pericentric heterochromatin assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090053 positive regulation of chromatin silencing at centromere Any process that increases the frequency, rate or extent of chromatin silencing at the centromere. Chromatin silencing at the centromere is the repression of transcription of centromeric DNA by altering the structure of chromatin. GO:0016113 polyterpenoid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016113 polyterpenoid degradation|polyterpenoid catabolism|polyterpenoid breakdown|polyterpene catabolic process|polyterpene catabolism The chemical reactions and pathways resulting in the breakdown of polyterpenoid compounds, terpenoids with more than eight isoprene units. GO:0090054 regulation of silent mating-type cassette heterochromatin assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090054 regulation of chromatin silencing at silent mating-type cassette Any process that modulates the frequency, rate, or extent of chromatin silencing at silent mating-type cassette. Chromatin silencing at silent mating-type cassette is the repression of transcription at silent mating-type loci by altering the structure of chromatin. GO:0090059 protoxylem development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090059 The process whose specific outcome is the progression of the protoxylem over time, from its formation to the mature structure. The protoxylem comprises the first formed elements of the primary xylem. GO:0090057 root radial pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090057 The radial pattern formation process that results in the formation of the different tissues of the root around its radial axis. GO:0090058 metaxylem development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090058 The process whose specific outcome is the progression of the metaxylem over time, from its formation to the mature structure. The metaxylem is the part of the primary xylem that differentiates after the protoxylem and before the secondary xylem, if any of the latter is formed. GO:0031726 CCR1 chemokine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031726 CCR1 chemokine receptor ligand|macrophage inflammatory protein-1 alpha receptor binding Interacting selectively and non-covalently with a CCR1 chemokine receptor. GO:0031727 CCR2 chemokine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031727 monocyte chemoattractant protein 1 receptor binding|CCR2 chemokine receptor ligand Interacting selectively and non-covalently with a CCR2 chemokine receptor. GO:0006768 biotin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006768 Wikipedia:Biotin vitamin H metabolism|vitamin B7 metabolic process|vitamin B7 metabolism|vitamin H metabolic process|biotin metabolism The chemical reactions and pathways involving biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions. GO:0031724 CXCR5 chemokine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031724 CXCR5 chemokine receptor ligand|type 1 Burkitt's lymphoma receptor binding Interacting selectively and non-covalently with a CXCR5 chemokine receptor. GO:0006769 nicotinamide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006769 MetaCyc:PWY-5083 niacin metabolism|niacin metabolic process|vitamin B3 metabolism|nicotinamide metabolism|vitamin B3 metabolic process The chemical reactions and pathways involving nicotinamide, pyridine-3-carboxamide, the amide of nicotinic acid. It is a member of the B complex of vitamins and occurs widely in living organisms. GO:0031725 CXCR6 chemokine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031725 CXCR6 chemokine receptor ligand|bonzo receptor binding|STRL33 receptor binding Interacting selectively and non-covalently with a CXCR6 chemokine receptor. GO:0006766 vitamin metabolic process biolink:BiologicalProcess go-plus goslim_yeast|goslim_candida|goslim_pir|goslim_aspergillus|goslim_pombe http://purl.obolibrary.org/obo/GO_0006766 vitamin metabolism The chemical reactions and pathways involving vitamins. Vitamin is a general term for a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. Vitamins may be water-soluble or fat-soluble and usually serve as components of coenzyme systems. GO:0031722 hemoglobin beta binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031722 Interacting selectively and non-covalently with a hemoglobin beta chain. GO:0031723 CXCR4 chemokine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031723 CXCR4 chemokine receptor ligand|stromal cell-derived factor 1 receptor binding Interacting selectively and non-covalently with a CXCR4 chemokine receptor. GO:0006767 water-soluble vitamin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006767 water-soluble vitamin metabolism The chemical reactions and pathways involving any of a diverse group of vitamins that are soluble in water. GO:0006764 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006764 GO:0031720 haptoglobin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031720 Interacting selectively and non-covalently with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex. GO:0031721 hemoglobin alpha binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031721 Interacting selectively and non-covalently with a hemoglobin alpha chain. GO:0006765 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006765 GO:0006762 obsolete dihydrofolate reduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006762 dihydrofolate reduction OBSOLETE. (Was not defined before being made obsolete). GO:0006763 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006763 GO:0006760 folic acid-containing compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006760 vitamin B9 and derivative metabolic process|folate-containing compound metabolism|folate and derivative metabolism|folate and derivative metabolic process|folate-containing compound metabolic process|vitamin B9 and derivative metabolism|folic acid-containing compound metabolism|folic acid and derivative metabolism|vitamin M and derivative metabolism|vitamin M and derivative metabolic process|folic acid and derivative metabolic process The chemical reactions and pathways involving a folic acid-containing compound, i.e. any of a group of heterocyclic compounds based on the pteroic acid skeleton conjugated with one or more L-glutamic acid or L-glutamate units. GO:0006761 dihydrofolate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006761 dihydrofolate biosynthesis|dihydrofolate anabolism|dihydrofolate synthesis|dihydrofolate formation|7,8-dihydrofolate biosynthesis|7,8-dihydrofolate biosynthetic process The chemical reactions and pathways resulting in the formation of dihydrofolate, the dihydroxylated derivative of folate. GO:0031728 CCR3 chemokine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031728 eosinophil eotaxin receptor binding|CCR3 chemokine receptor ligand Interacting selectively and non-covalently with a CCR3 chemokine receptor. GO:0031729 CCR4 chemokine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031729 CCR4 chemokine receptor ligand Interacting selectively and non-covalently with a CCR4 chemokine receptor. GO:0090028 positive regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090028 Any process that increases the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion. GO:0090029 negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090029 Any process that decreases the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion. GO:0090022 regulation of neutrophil chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090022 Any process that modulates the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding. GO:0090023 positive regulation of neutrophil chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090023 Any process that increases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding. GO:0090020 obsolete regulation of transcription involved in posterior neural plate formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090020 OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter contributing to the formation of the posterior neural plate. GO:0090021 positive regulation of posterior neural plate formation by Wnt signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090021 positive regulation of posterior neural plate formation by Wnt receptor signaling pathway|positive regulation of posterior neural plate formation by Wnt receptor signalling pathway|positive regulation of posterior neural plate formation by Wnt-activated signaling pathway The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and increasing the rate or extent of posterior neural plate formation. GO:0090026 positive regulation of monocyte chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090026 Any process that increases the frequency, rate, or extent of monocyte chemotaxis. GO:0090027 negative regulation of monocyte chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090027 Any process that decreases the frequency, rate, or extent of monocyte chemotaxis. GO:0090024 negative regulation of neutrophil chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090024 Any process that decreases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding. GO:0090025 regulation of monocyte chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090025 Any process that modulates the frequency, rate, or extent of monocyte chemotaxis. GO:0031715 C5L2 anaphylatoxin chemotactic receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031715 C5L2 anaphylatoxin chemotactic receptor ligand Interacting selectively and non-covalently with a C5L2 anaphylatoxin chemotactic receptor. GO:0031716 calcitonin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031716 calcitonin receptor ligand Interacting selectively and non-covalently with a calcitonin receptor. GO:0006779 porphyrin-containing compound biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006779 porphyrin biosynthetic process|porphyrin biosynthesis|porphyrin anabolism|porphyrin synthesis|porphyrin formation The chemical reactions and pathways resulting in the formation of any member of a large group of derivatives or analogs of porphyrin. Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group. GO:0031713 B2 bradykinin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031713 B2 bradykinin receptor ligand Interacting selectively and non-covalently with a B2 bradykinin receptor. GO:0031714 C5a anaphylatoxin chemotactic receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031714 C5a anaphylatoxin chemotactic receptor ligand Interacting selectively and non-covalently with a C5a anaphylatoxin chemotactic receptor. GO:0031711 bradykinin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031711 bradykinin receptor ligand Interacting selectively and non-covalently with a bradykinin receptor. GO:0006777 Mo-molybdopterin cofactor biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006777 MetaCyc:PWY-6823 Mo-molybdopterin cofactor formation|Moco biosynthesis|Moco biosynthetic process|molybdenum cofactor biosynthetic process|Mo-molybdopterin cofactor biosynthesis|Mo-molybdopterin cofactor anabolism|Mo-molybdopterin cofactor synthesis The chemical reactions and pathways resulting in the formation of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands. GO:0090030 regulation of steroid hormone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090030 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones. GO:0031712 B1 bradykinin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031712 B1 bradykinin receptor ligand Interacting selectively and non-covalently with a B1 bradykinin receptor. GO:0006778 porphyrin-containing compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006778 porphyrin metabolism|porphyrin metabolic process The chemical reactions and pathways involving any member of a large group of derivatives or analogs of porphyrin. Porphyrins consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group. GO:0006775 fat-soluble vitamin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006775 fat-soluble vitamin metabolism The chemical reactions and pathways involving of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water. GO:0031710 neuromedin B receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031710 neuromedin B receptor ligand Interacting selectively and non-covalently with a neuromedin B receptor. GO:0006776 vitamin A metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006776 vitamin A metabolism The chemical reactions and pathways involving any of the vitamin A compounds, retinol, retinal (retinaldehyde) and retinoic acid, all of which are derivatives of beta-carotene. GO:0006773 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006773 GO:0006774 obsolete vitamin B12 reduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006774 vitamin B12 reduction OBSOLETE. (Was not defined before being made obsolete). GO:0006771 riboflavin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006771 Wikipedia:Riboflavin vitamin G metabolic process|vitamin G metabolism|vitamin B2 metabolism|riboflavin metabolism|vitamin B2 metabolic process The chemical reactions and pathways involving riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD). GO:0006772 thiamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006772 Wikipedia:Thiamine vitamin B1 metabolic process|vitamin B1 metabolism|thiamine metabolism|thiamin metabolic process|thiamin metabolism The chemical reactions and pathways involving thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver. GO:0031719 type 2 cannabinoid receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031719 type 2 cannabinoid receptor ligand Interacting selectively and non-covalently with a type 2 cannabinoid receptor. GO:0006770 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006770 GO:0031717 cannabinoid receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031717 cannabinoid receptor ligand Interacting selectively and non-covalently with a cannabinoid receptor. GO:0031718 type 1 cannabinoid receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031718 type 1 cannabinoid receptor ligand Interacting selectively and non-covalently with a type 1 cannabinoid receptor. GO:0090039 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090039 GO:0090033 positive regulation of filamentous growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090033 Any process that increases the frequency, rate or extent of the process in which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape. GO:0090034 regulation of chaperone-mediated protein complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090034 Any process that modulates the frequency, rate, or extent of chaperone-mediated protein complex assembly. Chaperone-mediated protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex. GO:0090031 positive regulation of steroid hormone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090031 Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones. GO:0090032 negative regulation of steroid hormone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090032 Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones. GO:0090037 positive regulation of protein kinase C signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090037 positive regulation of protein kinase C signaling cascade|positive regulation of protein kinase C signalling cascade Any process that increases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound. GO:0090038 negative regulation of protein kinase C signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090038 negative regulation of protein kinase C signalling cascade|negative regulation of protein kinase C signaling cascade Any process that decreases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound. GO:0090035 positive regulation of chaperone-mediated protein complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090035 Any process that increases the frequency, rate, or extent of chaperone-mediated protein complex assembly. Chaperone-mediated protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex. GO:0090036 regulation of protein kinase C signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090036 regulation of protein kinase C signaling cascade|regulation of protein kinase C signalling cascade Any process that modulates the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound. GO:0031704 apelin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031704 apelin receptor ligand|APJ receptor binding Interacting selectively and non-covalently with an apelin receptor. GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signalling pathway The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands resulting in an increase in the rate or frequency of a MAPKKK cascade. GO:0006748 lipoamide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006748 lipoamide metabolism The chemical reactions and pathways involving lipoamide, the functional form of lipoic acid in which the carboxyl group is attached to protein by an amide linkage to a lysine amino group. GO:0090081 regulation of heart induction by regulation of canonical Wnt signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090081 regulation of heart induction by regulation of canonical Wnt-activated signaling pathway|regulation of heart induction by regulation of canonical Wnt receptor signaling pathway|regulation of heart induction by regulation of canonical Wnt receptor signalling pathway Any process that modulates the rate, frequency or extent of canonical Wnt signaling pathway that regulates heart induction. Canonical Wnt signaling pathway involved in heart induction is the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell, followed by relaying of the signal via beta-catenin, and ending with a change in transcription of target genes. GO:0031705 bombesin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031705 bombesin receptor ligand Interacting selectively and non-covalently with a bombesin receptor. GO:0006749 glutathione metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006749 glutathione metabolism|oxidized glutathione reduction The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle. GO:0006746 FADH2 metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006746 FADH2 metabolism|reduced flavin adenine dinucleotide metabolic process The chemical reactions and pathways involving the reduced form of flavin adenine dinucleotide. GO:0031702 type 1 angiotensin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031702 type 1 angiotensin receptor ligand|AT1 receptor binding Interacting selectively and non-covalently with a type 1 angiotensin receptor. GO:0031703 type 2 angiotensin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031703 AT2 receptor binding|type 2 angiotensin receptor ligand Interacting selectively and non-covalently with a type 2 angiotensin receptor. GO:0006747 FAD biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006747 oxidized flavin adenine dinucleotide biosynthesis|oxidized flavin adenine dinucleotide biosynthetic process|oxidized flavin-adenine dinucleotide biosynthesis|oxidized flavin-adenine dinucleotide biosynthetic process|FAD biosynthesis|FAD anabolism|FAD synthesis|FAD formation The chemical reactions and pathways resulting in the formation of FAD, the oxidized form of flavin-adenine dinucleotide. GO:0006744 ubiquinone biosynthetic process biolink:BiologicalProcess go-plus goslim_pombe http://purl.obolibrary.org/obo/GO_0006744 MetaCyc:UBISYN-PWY coenzyme Q8 biosynthetic process|coenzyme Q8 biosynthesis|coenzyme Q9 biosynthetic process|coenzyme Q10 biosynthesis|ubiquinone synthesis|coenzyme Q9 biosynthesis|coenzyme Q10 biosynthetic process|ubiquinone formation|coenzyme Q biosynthetic process|coenzyme Q biosynthesis|ubiquinone biosynthesis|ubiquinone anabolism|coenzyme Q6 biosynthesis|coenzyme Q6 biosynthetic process The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme. GO:0031700 adrenomedullin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031700 adrenomedullin receptor ligand Interacting selectively and non-covalently with an adrenomedullin receptor. GO:0090084 negative regulation of inclusion body assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090084 Any process that decreases the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body. GO:0006745 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006745 GO:0090085 regulation of protein deubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090085 Any process that modulates the frequency, rate or extent of protein deubiquitination. Protein deubiquitination is the removal of one or more ubiquitin groups from a protein. GO:0031701 angiotensin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031701 angiotensin receptor ligand Interacting selectively and non-covalently with an angiotensin receptor. GO:0090082 positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090082 positive regulation of heart induction by negative regulation of canonical Wnt receptor signaling pathway|positive regulation of heart induction by negative regulation of canonical Wnt receptor signalling pathway|positive regulation of heart induction by negative regulation of canonical Wnt-activated signaling pathway Any process that decreases the rate, frequency or extent of canonical Wnt signaling pathway that positively regulates heart induction. Canonical Wnt signaling pathway involved in heart induction is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. GO:0006742 NADP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006742 nicotinamide adenine dinucleotide phosphate catabolic process|NADP catabolism|NADP (reduced) catabolic process|reduced nicotinamide adenine dinucleotide phosphate catabolic process|reduced NADP catabolism|NADP (oxidized) catabolic process|oxidized NADP catabolic process|oxidized nicotinamide adenine dinucleotide phosphate catabolism|NADPH catabolic process|NADPH catabolism|NADP degradation|oxidized NADP catabolism|oxidized nicotinamide adenine dinucleotide phosphate catabolic process|NADP (oxidized) catabolism|NADP breakdown|reduced nicotinamide adenine dinucleotide phosphate catabolism|reduced NADP catabolic process|NADP (reduced) catabolism|nicotinamide adenine dinucleotide phosphate catabolism The chemical reactions and pathways resulting in the breakdown of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; catabolism may be of either the oxidized form, NADP, or the reduced form, NADPH. GO:0090083 regulation of inclusion body assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090083 Any process that modulates the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body. GO:0006743 ubiquinone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006743 coenzyme Q metabolism|ubiquinone metabolism|coenzyme Q metabolic process The chemical reactions and pathways involving ubiquinone, a lipid-soluble electron-transporting coenzyme. GO:0006740 NADPH regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006740 reduced NADP regeneration|reduced nicotinamide adenine dinucleotide phosphate regeneration|NADP (reduced) regeneration A metabolic process that generates a pool of NADPH by the reduction of NADP+. GO:0006741 NADP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006741 NADP synthesis|NADP formation|NADP biosynthesis|reduced NADP biosynthetic process|reduced NADP biosynthesis|oxidized nicotinamide adenine dinucleotide phosphate biosynthetic process|oxidized nicotinamide adenine dinucleotide phosphate biosynthesis|NADPH biosynthetic process|NADPH biosynthesis|oxidized NADP biosynthetic process|oxidized NADP biosynthesis|NADP (oxidized) biosynthesis|NADP (oxidized) biosynthetic process|reduced nicotinamide adenine dinucleotide phosphate biosynthesis|reduced nicotinamide adenine dinucleotide phosphate biosynthetic process|NADP (reduced) biosynthesis|NADP (reduced) biosynthetic process|nicotinamide adenine dinucleotide phosphate biosynthetic process|nicotinamide adenine dinucleotide phosphate biosynthesis|NADP anabolism The chemical reactions and pathways resulting in the formation of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; biosynthesis may be of either the oxidized form, NADP, or the reduced form, NADPH. GO:0031708 endothelin B receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031708 endothelin B receptor ligand Interacting selectively and non-covalently with an endothelin B receptor. GO:0031709 gastrin-releasing peptide receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031709 GRP receptor binding|gastrin-releasing peptide receptor ligand Interacting selectively and non-covalently with a gastrin-releasing peptide receptor. GO:0031706 subtype 3 bombesin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031706 subtype 3 bombesin receptor ligand Interacting selectively and non-covalently with a subtype 3 bombesin receptor. GO:0031707 endothelin A receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031707 endothelin A receptor ligand|endothelin-1 receptor binding Interacting selectively and non-covalently with an endothelin A receptor. CHEBI:32587 2-hydroxybenzoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32587 GO:0090088 regulation of oligopeptide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090088 Any process that modulates the frequency, rate or extent of the directed movement of oligopeptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages. GO:0090089 regulation of dipeptide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090089 Any process that modulates the rate, frequency or extent of dipeptide transport. Dipeptide transport is the directed movement of a dipeptide, a combination of two amino acids by means of a peptide (-CO-NH-) link, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0090086 negative regulation of protein deubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090086 Any process that decreases the frequency, rate or extent of protein deubiquitination. Protein deubiquitination is the removal of one or more ubiquitin groups from a protein. GO:0090087 regulation of peptide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090087 Any process that modulates the frequency, rate or extent of the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0090091 positive regulation of extracellular matrix disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090091 Any process that increases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix. GO:0006759 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006759 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090092 regulation of transmembrane receptor protein serine/threonine kinase signalling pathway Any process that modulates the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand. GO:0006757 ATP generation from ADP biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006757 ADP phosphorylation The process of introducing a phosphate group into ADP, adenosine diphosphate, to produce ATP. GO:0090090 negative regulation of canonical Wnt signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090090 negative regulation of catenin protein nuclear translocation|negative regulation of Wnt receptor signaling pathway through beta-catenin|negative regulation of canonical Wnt receptor signaling pathway|negative regulation of canonical Wnt receptor signalling pathway|negative regulation of catenin import into nucleus|negative regulation of canonical Wnt-activated signaling pathway Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. GO:0006758 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006758 GO:0090095 regulation of metanephric cap mesenchymal cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090095 Any process that modulates the frequency, rate, or extent of metanephric cap mesenchymal cell proliferation. Metanephric cap mesenchymal cell proliferation is the multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip. GO:0006755 obsolete carbamoyl phosphate-ADP transphosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006755 carbamoyl phosphate-ADP transphosphorylation OBSOLETE. (Was not defined before being made obsolete). GO:0090096 positive regulation of metanephric cap mesenchymal cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090096 Any process that increases the frequency, rate, or extent of metanephric cap mesenchymal cell proliferation. Metanephric cap mesenchymal cell proliferation is the multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip. GO:0006756 AMP phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006756 The process of introducing a phosphate group into AMP, adenosine monophosphate, to produce ADP. Addition of two phosphate groups produces ATP. GO:0090093 regulation of fungal-type cell wall beta-glucan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090093 Any process that modulates the frequency, rate or extent of fungal-type cell wall beta-glucan biosynthesis, the chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells. GO:0006753 nucleoside phosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006753 nucleoside phosphate metabolism The chemical reactions and pathways involving any phosphorylated nucleoside. GO:0090094 metanephric cap mesenchymal cell proliferation involved in metanephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090094 The multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip. GO:0006754 ATP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006754 ATP anabolism|ATP regeneration|ATP synthesis|ATP biosynthesis|ATP formation The chemical reactions and pathways resulting in the formation of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. GO:0006751 glutathione catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006751 glutathione catabolism|glutathione degradation|glutathione breakdown The chemical reactions and pathways resulting in the breakdown of glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins. GO:0006752 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006752 UBERON:0007719 bone of reproductive organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007719 baculum|os penis/os clitoris A bone that is part of a reproductive organ. GO:0006750 glutathione biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006750 MetaCyc:GLUTATHIONESYN-PWY glutathione synthesis|glutathione formation|glutathione biosynthesis|glutathione anabolism The chemical reactions and pathways resulting in the formation of glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins. UBERON:0007721 interphalangeal joint of pes biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007721 interphalangeal joint of foot|toe joint|foot interphalangeal joint|interphalangeal joint of toe|hindlimb digit inter-phalangeal joint The interphalangeal articulations of the foot (articulations of the phalanges) are ginglymoid joints, and each has a plantar and two collateral ligaments. The arrangement of these ligaments is similar to that in the metatarsophalangeal articulations: the Extensor tendons supply the places of dorsal ligaments. UBERON:0007722 interphalangeal joint of manus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007722 interphalangeal joint of hand|interphalangeal joint of finger|articulationes interphalangeae manus|articulationes digitorum manus|IP joint|articulations of the digits|interphalangeal joints of hand|interphalangeal articulations of hand The interphalangeal articulations of hand are hinge-joints of the phalanges of the hand. There are two sets (except in the thumb): 'proximal interphalangeal joints' (PIP), those between the first (also called proximal) and second (intermediate) phalanges 'distal interphalangeal joints' (DIP), those between the second and third (distal) phalanges A similar group of articulations also function in the toes. GO:0090099 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090099 GO:0090097 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090097 GO:0090098 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090098 GO:0006726 eye pigment biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006726 eye pigment anabolism|eye pigment synthesis|eye pigment biosynthesis|eye pigment formation The chemical reactions and pathways resulting in the formation of eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye. GO:0006727 ommochrome biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006727 ommochrome biosynthesis|ommochrome anabolism|ommochrome synthesis|ommochrome formation The chemical reactions and pathways resulting in the formation of ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye. GO:0006724 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006724 GO:0006725 cellular aromatic compound metabolic process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0006725 aromatic compound metabolism|aromatic hydrocarbon metabolism|aromatic hydrocarbon metabolic process The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells. GO:0090062 regulation of trehalose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090062 Any process that modulates the frequency, rate or extent of trehalose metabolism, the chemical reactions and pathways involving trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi. GO:0006722 triterpenoid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006722 triterpene metabolism|triterpene metabolic process|triterpenoid metabolism The chemical reactions and pathways involving triterpenoid compounds, terpenoids with six isoprene units. GO:0090063 positive regulation of microtubule nucleation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090063 Any process that increases the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell. GO:0006723 cuticle hydrocarbon biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006723 cuticle hydrocarbon biosynthesis|cuticle hydrocarbon anabolism|cuticle hydrocarbon synthesis|cuticle hydrocarbon formation The chemical reactions and pathways resulting in the formation of hydrocarbons that make up the cuticle, the outer layer of some animals and plants, which acts to prevent water loss. GO:0006720 isoprenoid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006720 isoprenoid metabolism|polyisoprenoid metabolic process|polyterpene metabolism|polyterpene metabolic process|polyisoprenoid metabolism The chemical reactions and pathways involving isoprenoid compounds, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues. GO:0090060 regulation of metaxylem development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090060 Any process that modulates the frequency, rate, or extent of metaxylem development. Metaxylem development is the process whose specific outcome is the progression of the metaxylem over time, from its formation to the mature structure. The metaxylem is the part of the primary xylem that differentiates after the protoxylem and before the secondary xylem, if any of the latter is formed. GO:0090061 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090061 GO:0006721 terpenoid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006721 terpenoid metabolism The chemical reactions and pathways involving terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure and including derivatives with various functional groups. CHEBI:32568 lysine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32568 CHEBI:32563 lysinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32563 CHEBI:32564 lysinium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32564 CHEBI:32565 lysinium(2+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32565 GO:0090066 regulation of anatomical structure size biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090066 Any process that modulates the size of an anatomical structure. GO:0090067 regulation of thalamus size biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090067 Any process that modulates the size of the thalamus. The thalamus is a part of the diencephalon that is composed of the dorsal thalamus and the ventral thalamus. GO:0090064 activation of microtubule nucleation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090064 Any process that starts the inactive process of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell. GO:0090065 regulation of production of siRNA involved in RNA interference biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090065 regulation of RNA interference, production of siRNA Any process that modulates the frequency, rate or extent of the production of siRNA, the cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of RNA interference. GO:0006728 pteridine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006728 pterin biosynthesis|pterin biosynthetic process|pteridine biosynthesis|pteridine anabolism|pteridine synthesis|pteridine formation The chemical reactions and pathways resulting in the formation of pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group. GO:0090068 positive regulation of cell cycle process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090068 Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. GO:0006729 tetrahydrobiopterin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006729 tetrahydrobiopterin anabolism|tetrahydrobiopterin synthesis|tetrahydrobiopterin formation|tetrahydrobiopterin biosynthesis|5,6,7,8-tetrahydrobiopterin biosynthetic process The chemical reactions and pathways resulting in the formation of tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine. GO:0090069 regulation of ribosome biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090069 Any process that modulates the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits. GO:0006737 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006737 GO:0006738 nicotinamide riboside catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006738 nicotinamide riboside catabolism|nicotinamide riboside degradation|nicotinamide riboside breakdown|N-ribosylnicotinamide catabolic process The chemical reactions and pathways resulting in the breakdown of nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide. GO:0090070 positive regulation of ribosome biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090070 Any process that increases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits. GO:0006735 NADH regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006735 NAD (reduced) regeneration|reduced NAD regeneration|reduced nicotinamide adenine dinucleotide regeneration A metabolic process that generates a pool of NADH by the reduction of NAD+. GO:0006736 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006736 GO:0006733 obsolete oxidoreduction coenzyme metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006733 oxidoreduction coenzyme metabolism OBSOLETE. The chemical reactions and pathways involving coenzymes that are required, in addition to an enzyme and a substrate, for an oxidoreductase reaction to proceed. GO:0090073 positive regulation of protein homodimerization activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090073 Any process that increases the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer. GO:0006734 NADH metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006734 NAD (reduced) metabolic process|NAD (reduced) metabolism|reduced NAD metabolism|reduced nicotinamide adenine dinucleotide metabolic process|reduced nicotinamide adenine dinucleotide metabolism|NADH metabolism|reduced NAD metabolic process The chemical reactions and pathways involving reduced nicotinamide adenine dinucleotide (NADH), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid. GO:0090074 negative regulation of protein homodimerization activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090074 Any process that decreases the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer. GO:0090071 negative regulation of ribosome biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090071 Any process that decreases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits. GO:0006731 obsolete coenzyme and prosthetic group metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006731 coenzyme and prosthetic group metabolic process OBSOLETE. The chemical reactions and pathways involving coenzymes and prosthetic groups. GO:0006732 obsolete coenzyme metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006732 group transfer coenzyme metabolic process|coenzyme and prosthetic group metabolism|coenzyme metabolism|coenzyme and prosthetic group metabolic process|group transfer coenzyme metabolism OBSOLETE. The chemical reactions and pathways involving coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed. GO:0090072 obsolete positive regulation of sodium ion transport via voltage-gated sodium channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090072 positive regulation of sodium ion transport via voltage-gated sodium channel activity OBSOLETE. Any process that activates or increases the frequency, rate or extent of the directed movement of sodium ions via the activity of voltage-gated sodium channels. CHEBI:32579 lysinium residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32579 GO:0006730 one-carbon metabolic process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0006730 UM-BBD_pathwayID:C1cyc one carbon metabolic process|one carbon metabolism|one-carbon transfer metabolic process|one-carbon metabolism|one-carbon transfer metabolism The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states. CHEBI:32571 perosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32571 UBERON:0007702 tract of brain biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007702 brain tract|landmark tracts An axon tract that is part of a brain. UBERON:0007703 spinothalamic tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007703 A tract that originates from neurons in the spinal central gray and projects to various somatosensory nuclei of the thalamus. It is formed in the medulla by merger of the anterior spinothalamic tract and lateral spinothalamic tract (adapted from Braininfo.org) GO:0090077 foam cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090077 The process in which a relatively unspecialized cell acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions. GO:0090078 smooth muscle derived foam cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090078 The process in which a smooth muscle cell acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions. GO:0090075 relaxation of muscle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090075 A process in which the extent of muscle contraction is reduced. Muscle relaxation can involve a number of processes including the removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases. In some muscles, calcium-independent pathways also play a role in muscle relaxation by decreasing the phosphorylation state of myosin light chain. GO:0090076 relaxation of skeletal muscle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090076 A process in which the extent of skeletal muscle tissue contraction is reduced. Muscle relaxation involves the removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases. GO:0006739 NADP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006739 oxidized nicotinamide adenine dinucleotide phosphate metabolic process|NADP metabolism|reduced NADP metabolism|reduced NADP metabolic process|oxidized nicotinamide adenine dinucleotide phosphate metabolism|NADPH metabolism|oxidized NADP metabolism|NADP (oxidized) metabolism|NAD phosphorylation and dephosphorylation|reduced nicotinamide adenine dinucleotide phosphate metabolism|NADP (reduced) metabolism|nicotinamide adenine dinucleotide phosphate metabolism|nicotinamide adenine dinucleotide phosphate metabolic process|NADP (reduced) metabolic process|reduced nicotinamide adenine dinucleotide phosphate metabolic process|NADP (oxidized) metabolic process|oxidized NADP metabolic process|NADPH metabolic process The chemical reactions and pathways involving nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; metabolism may be of either the oxidized form, NADP, or the reduced form, NADPH. GO:0090079 translation regulator activity, nucleic acid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0090079 Any selective and non-covalent interaction with a nucleic acid involved in the initiation, activation, perpetuation, repression or termination of polypeptide synthesis at the ribosome. FAO:0000038 macroconidium biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/FAO_0000038 The larger of two types of asexual spores formed by some fungi; usually round or oblong. FAO:0000039 oospore biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/FAO_0000039 An asexual spore formed by Oomycetes; formed upon fertilization of an oosphere. CHEBI:4116 D-erythrulose 4-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_4116 GO:0090206 negative regulation of cholesterol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090206 Any process that decreases the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. GO:0090207 regulation of triglyceride metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090207 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol. GO:0090204 protein localization to nuclear pore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090204 protein localisation to nuclear pore A process in which a protein is transported to, or maintained in, a nuclear pore. GO:0090205 positive regulation of cholesterol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090205 Any process that increases the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. GO:0090208 positive regulation of triglyceride metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090208 Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol. GO:0090209 negative regulation of triglyceride metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090209 Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol. GO:0090202 gene looping biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090202 The formation and maintenance of DNA loops that juxtapose sequentially separated regions of RNA polymerase II-transcribed genes. GO:0090203 transcriptional activation by promoter-terminator looping biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090203 transcriptional activation by memory gene loops The formation and maintenance of DNA loops that juxtapose the promoter and terminator regions of RNA polymerase II-transcribed genes and activate transcription from an RNA polymerase II promoter. GO:0090200 positive regulation of release of cytochrome c from mitochondria biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090200 Any process that increases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation. GO:0090201 negative regulation of release of cytochrome c from mitochondria biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090201 Any process that decreases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation. FAO:0000047 cleistothecium biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/FAO_0000047 A completely closed fruiting body formed by some fungi of the Ascomycota, containing asci. FAO:0000048 Hulle cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/FAO_0000048 A specialized multinucleate cell that originates from a nest-like aggregation of hyphae during sexual development. Hulle cells serve as nurse cells to the developing cleistothecium. CHEBI:136181 N-[(+)-12-hydroxy-7-isojasmonyl]-L-isoleucinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136181 CHEBI:136182 tuberonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136182 CHEBI:136180 N-[(+)-7-isojasmonyl]-L-isoleucinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136180 FAO:0000041 arthroconidium biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/FAO_0000041 arthrospore A cylindrical spore formed by development and compartmentation of hyphae; the hyphae are often supporting blastoconidiophores. FAO:0000042 blastoconidium biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/FAO_0000042 blastospore|reproductive blastospore An oblong or round asexual reproductive spore formed specifically by budding. FAO:0000043 conidiophore biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/FAO_0000043 A specialized hypha, often aerial, that gives rise to asexual spores known as conidia. FAO:0000044 sterigma biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/FAO_0000044 sterigmata (plural) A small hyphal branch or structure which supports a sporangium, a conidium, or a basidiospore. In species with biseriate (two-layered) sterigmata such as A. nidulans, the first layer comprises primary sterigmata (metulae) and the second layer secondary sterigmata (phialides). Some species, e.g. A. fumigatus, A. oryzae, and others, have only phialides. FAO:0000045 phialide biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/FAO_0000045 secondary sterigma A specialized cell that buds from a metula on a developing conidiophore. Multiple phialides may bud from each metula. The phialides in turn divide asymmetrically to give rise to chains of conidia. FAO:0000046 metula biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/FAO_0000046 metulae (plural)|primary sterigma A specialized cell borne on a conidiophore that gives rise to phialides during the process of conidiation. GO:0090217 negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090217 Any process that decreases the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate. GO:0090218 positive regulation of lipid kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090218 Any process that increases the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid. GO:0090215 regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090215 Any process that modulates the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate. GO:0090216 positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090216 Any process that increases the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate. CHEBI:4126 D-fructofuranuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_4126 GO:0090219 negative regulation of lipid kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090219 Any process that decreases the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid. GO:0090210 regulation of establishment of blood-brain barrier biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090210 regulation of establishment of BBB Any process that modulates the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain. GO:0090213 regulation of radial pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090213 regulation of radial pattern specification Any process that modulates the rate, frequency or extent of radial pattern formation, the regionalization process that results in defined areas around a point in which specific types of cell differentiation will occur. GO:0090214 spongiotrophoblast layer developmental growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090214 The increase in size or mass of the spongiotrophoblast layer of the placenta where the increase in size or mass contributes to the progression of that layer over time from its formation to its mature state. CHEBI:136179 (+)-7-isojasmonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136179 GO:0090211 positive regulation of establishment of blood-brain barrier biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090211 positive regulation of establishment of BBB Any process that increases the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain. GO:0090212 negative regulation of establishment of blood-brain barrier biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090212 negative regulation of establishment of BBB Any process that decreases the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain. FAO:0000014 ascus biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/FAO_0000014 A sac-like structure containing sexual spores formed by Ascomycotina; mature asci may have little or no cytoplasm or cytoplasmic contents, and no nucleus outside of the spores. GO:0016290 palmitoyl-CoA hydrolase activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0016290 MetaCyc:PWY-5148|RHEA:16645|EC:3.1.2.2|MetaCyc:PALMITOYL-COA-HYDROLASE-RXN long-chain fatty-acyl-CoA hydrolase activity|palmityl thioesterase activity|palmitoyl-CoA deacylase activity|palmitoyl thioesterase activity|palmityl-CoA deacylase activity|palmityl thioesterase I|palmitoyl coenzyme A hydrolase activity|fatty acyl thioesterase I Catalysis of the reaction: palmitoyl-CoA + H2O = CoA + palmitate. GO:0016291 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016291 GO:0016292 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016292 FAO:0000017 sexual spore biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/FAO_0000017 meiotically-derived spore A spore formed following meiosis. In some species, prospores formed by meiosis may undergo one or more rounds of mitosis before they are fully mature. FAO:0000018 unicellular structure biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/FAO_0000018 cell A fungal structure that comprises a single cell. An individual cell is composed of a plasma membrane, contents internal to the plasma membrane, and any external protective or encapsulating structure. FAO:0000019 spore biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/FAO_0000019 A spore produced by a fungus. A spore is a differentiated form of an organism produced during or as a result of an asexual or sexual reproductive process; usually a cell with a thick cell wall that stores and protects one or more nuclei. Spores may be produced in response to, and are characteristically resistant to, adverse environmental conditions. FAO:0000010 sporophore biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/FAO_0000010 spore-bearing structure|fruitbody|fruiting body|fruit body|sporocarp|spore-producing structure A multicellular anatomical structure that functions in the production of spores, which are directly borne upon or within sporogenous cells that form part of the sporophore. FAO:0000011 mycelium biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/FAO_0000011 A group or mass of discrete hyphae; the vegetative structure of many fungi. FAO:0000012 basidiocarp biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/FAO_0000012 mushroom A large fruiting body that is composed of masses of intertwined hyphal elements and produces basidia and basidiospores. The basidiocarp is characteristic of the majority of fungi of the subphylum Basidiomycotina, in which it is the site of karyogamy and meiosis. Mushrooms and toadstools are common examples. GO:0016286 small conductance calcium-activated potassium channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016286 SK KCa channels|SK calcium-activated potassium channel activity|small conductance KCa channels Enables the transmembrane transfer of potassium by a channel with a unit conductance of 2 to 20 picoSiemens that opens in response to stimulus by internal calcium ions. Small conductance calcium-activated potassium channels are more sensitive to calcium than are large conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism. CHEBI:136141 lysophosphatidylethanolamine 22:4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136141 GO:0016287 glycerone-phosphate O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016287 MetaCyc:2.3.1.42-RXN|Reactome:R-HSA-75879|Reactome:R-HSA-1483002|EC:2.3.1.42|KEGG_REACTION:R01013|RHEA:17657 acyl-CoA:glycerone-phosphate O-acyltransferase activity|dihydroxyacetone phosphate acyltransferase activity Catalysis of the reaction: acyl-CoA + glycerone phosphate = 1-acylglycerone 3-phosphate + CoA. CHEBI:136142 lysophosphatidylethanolamine O-18:1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136142 GO:0016288 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016288 GO:0016289 CoA hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016289 Reactome:R-HSA-193385 Catalysis of the reaction: X-CoA + H2O = X + CoA; X may be any group. GO:0016282 eukaryotic 43S preinitiation complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016282 eukaryotic 43S pre-initiation complex A protein complex composed of the 40S ribosomal subunit plus eIF1A, eIF3, and eIF2-GTP-bound methionyl-initiator methionine tRNA. GO:0016283 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016283 GO:0016284 obsolete alanine aminopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016284 EC:3.4.11.- alanine aminopeptidase activity OBSOLETE. Catalysis of the release of an N-terminal amino acid, preferentially alanine, from an oligopeptide or polypeptide. GO:0016285 obsolete cytosol alanyl aminopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016285 MetaCyc:3.4.11.14-RXN|EC:3.4.11.14 puromycin-sensitive aminopeptidase activity|aminopolypeptidase activity|human liver aminopeptidase|arylamidase activity|cytosol aminopeptidase III activity|cytosol alanyl aminopeptidase activity|thiol-activated aminopeptidase activity|soluble alanyl aminopeptidase activity|liver aminopeptidase activity OBSOLETE. Catalysis of the release of an N-terminal amino acid, preferentially alanine, from a wide range of peptides, amides and arylamides. FAO:0000026 urediniospore biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/FAO_0000026 uredospore|urediospore A thin-walled spore that is formed in a uredinium and is the primary dispersal mode for rust-causing Basidiomycete fungi. FAO:0000021 basidiospore biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/FAO_0000021 A thick-walled spore formed externally on extrusions of a basidium following sexual reproduction; found in Basidiomycetes. FAO:0000022 teliospore biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/FAO_0000022 A diploid spore with a thick, pigmented, sculpted cell wall, and extracellular peptidoglycan spikes that is formed during growth in a plant host by some Basidiomycete species, including pathogenic smut (Ustilaginales) and rust (Pucciniales) fungi. FAO:0000023 asexual spore biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/FAO_0000023 mitotically-derived spore A spore formed following one or more rounds of mitosis, without meiosis. FAO:0000024 conidium biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/FAO_0000024 An asexual, nonmotile spore formed by higher fungi. Conidia are usually made from the side or tip of specialized sporogenous cells and do not form by progressive cleavage of the cytoplasm. GO:0016297 acyl-[acyl-carrier-protein] hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016297 EC:3.1.2.14|RHEA:30131|Reactome:R-HSA-5655955|MetaCyc:RXN-7902 S-acyl fatty acid synthase thioesterase activity|acyl-ACP thioesterase activity|acyl-acyl carrier protein hydrolase activity|acyl-ACP-hydrolase activity|acyl-acyl-carrier-protein hydrolase activity|acyl-ACP hydrolase activity|acyl-[acyl-carrier protein] hydrolase activity Catalysis of the reaction: acyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + a fatty acid. GO:0016298 lipase activity biolink:MolecularActivity go-plus goslim_chembl|goslim_drosophila|goslim_aspergillus http://purl.obolibrary.org/obo/GO_0016298 Reactome:R-HSA-163432|Reactome:R-HSA-163402|EC:3.1.1.- Catalysis of the hydrolysis of a lipid or phospholipid. GO:0016299 obsolete regulator of G-protein signaling activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016299 regulator of G protein signaling activity|regulator of G protein signalling activity|regulator of G-protein signalling activity|regulator of G-protein signaling activity|RGS OBSOLETE. Inhibits signal transduction the GTPase activity of G-protein alpha subunits, thereby driving them into their inactive GDP-bound form. GO:0016293 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016293 GO:0016294 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016294 GO:0016295 myristoyl-[acyl-carrier-protein] hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016295 EC:3.1.2.14|RHEA:30123|KEGG_REACTION:R08159|MetaCyc:RXN-10727 tetradecanoyl-ACP hydrolase activity|myristoyl-[acyl-carrier protein] hydrolase activity|tetradecanoyl-[acyl-carrier-protein] hydrolase activity|myristoyl-ACP hydrolase activity Catalysis of the reaction: myristoyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + myristate. GO:0016296 palmitoyl-[acyl-carrier-protein] hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016296 RHEA:41932|EC:3.1.2.14|KEGG_REACTION:R08162|MetaCyc:RXN-9549 palmitoyl-ACP hydrolase activity|palmitoyl-[acyl-carrier protein] hydrolase activity Catalysis of the reaction: palmitoyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + palmitate. GO:0016270 O-glycan processing, core 4 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016270 The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 4 O-glycan structure, GlcNAc-beta-(1->6)[GalNAc-beta-(1->3)]-GalNAc. GO:0090248 cell migration involved in somitogenic axis elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090248 cell motility involved in somitogenic axis elongation Any process involved in the controlled self-propelled movement of a cell that contributes to somitogenic axis elongation. GO:0090249 regulation of cell migration involved in somitogenic axis elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090249 regulation of cell motility involved in somitogenic axis elongation Any process that modulates the frequency, rate, or extent of the controlled self-propelled movement of a cell that contributes to somitogenic axis elongation. GO:0016268 O-glycan processing, core 2 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016268 The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 2 O-glycan structure, GlcNAc-beta-(1->6)[Gal-beta-(1->3)]-GalNAc. GO:0016269 O-glycan processing, core 3 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016269 The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 3 O-glycan structure, GlcNAc-beta-(1->3)-GalNAc. GO:0090242 retinoic acid receptor signaling pathway involved in somitogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090242 retinoic acid receptor signalling pathway involved in somitogenesis The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that contributes to somitogenesis. GO:0016264 gap junction assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016264 Assembly of gap junctions, which are found in most animal tissues, and serve as direct connections between the cytoplasms of adjacent cells. They provide open channels through the plasma membrane, allowing ions and small molecules (less than approximately a thousand daltons) to diffuse freely between neighboring cells, but preventing the passage of proteins and nucleic acids. GO:0016265 obsolete death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016265 Wikipedia:Death OBSOLETE. A permanent cessation of all vital functions: the end of life; can be applied to a whole organism or to a part of an organism. GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090243 fibroblast growth factor receptor signalling pathway involved in somitogenesis The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to somitogenesis. CHEBI:4153 D-galactopyranuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_4153 GO:0090240 positive regulation of histone H4 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090240 Any process that increases the rate, frequency, or extent of histone H4 acetylation, the modification of histone H4 by the addition of an acetyl group. GO:0016266 O-glycan processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016266 The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form a core O-glycan structure. GO:0090241 negative regulation of histone H4 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090241 Any process that decreases the rate, frequency, or extent of histone H4 acetylation, the modification of histone H4 by the addition of an acetyl group. GO:0016267 O-glycan processing, core 1 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016267 The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 1 O-glycan structure, Gal-beta-(1->3)-GalNAc. GO:0090246 convergent extension involved in somitogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090246 The morphogenetic process in which a presomitic mesoderm narrows along the left-right axis and lengthens in the rostral-caudal axis contributing to somitogenesis. GO:0016260 selenocysteine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016260 selenocysteine anabolism|selenocysteine synthesis|selenocysteine formation|selenocysteine biosynthesis The chemical reactions and pathways resulting in the formation of selenocysteine, an essential component of glutathione peroxidase and some other proteins. GO:0090247 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090247 GO:0016261 selenocysteine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016261 selenocysteine degradation|selenocysteine breakdown|selenocysteine catabolism The chemical reactions and pathways resulting in the breakdown of selenocysteine, an essential component of glutathione peroxidase and some other proteins. GO:0016262 protein N-acetylglucosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016262 EC:2.4.1.94|RHEA:16533|MetaCyc:2.4.1.94-RXN UDP-N-acetyl-D-glucosamine:protein beta-N-acetyl-D-glucosaminyl-transferase activity|N-GlcNAc transferase activity|uridine diphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-protein acetylglucosaminyltransferase activity|UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + protein = UDP + 4-N-(N-acetyl-D-glucosaminyl)-protein. GO:0090244 Wnt signaling pathway involved in somitogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090244 Wnt-activated signaling pathway involved in somitogenesis|Wnt receptor signalling|Wnt receptor signaling pathway involved in somitogenesis The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state that contributes to somitogenesis. GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016263 RHEA:15621|Reactome:R-HSA-1964505|MetaCyc:2.4.1.122-RXN|EC:2.4.1.122|Reactome:R-HSA-6785524 UDPgalactose:glycoprotein-N-acetyl-D-galactosamine 3-beta-D-galactosyltransferase activity|UDP-galactose:glycoprotein-N-acetyl-D-galactosamine 3-beta-D-galactosyltransferase activity|uridine diphosphogalactose-mucin beta-(1->3)-galactosyltransferase activity|Core 1 GalT Catalysis of the addition of a galactosyl residue to a non-reducing O-linked N-acetylgalactosamine residue in an O-glycan. GO:0090245 axis elongation involved in somitogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090245 The developmental growth that results in the elongation of the rostral-caudal axis that contributes to somitogenesis. FAO:0000003 basidium biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/FAO_0000003 A spore-producing structure found in a Basidiomycete; formed when the terminal cell of a dikaryotic hyphal branch inflates and undergoes karyogamy and meiosis. GO:0016280 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016280 GO:0016281 eukaryotic translation initiation factor 4F complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016281 eIF-4F|eukaryotic translation initiation factor 4 complex The eukaryotic translation initiation factor 4F complex is composed of eIF4E, eIF4A and eIF4G; it is involved in the recognition of the mRNA cap, ATP-dependent unwinding of the 5'-terminal secondary structure and recruitment of the mRNA to the ribosome. CHEBI:4170 D-glucopyranose 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_4170 FAO:0000007 fruitbody biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/FAO_0000007 fruiting body Any specialized structure which bears or contains sexually or asexually derived spores. GO:0031898 chromoplast envelope biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031898 The double lipid bilayer enclosing the chromoplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space. GO:0090250 cell-cell adhesion involved in establishment of planar polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090250 The attachment of one cell to another cell via adhesion molecules that contributes to the establishment of planar cell polarity. GO:0031899 chromoplast inner membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031899 The inner, i.e. lumen-facing, lipid bilayer of the chromoplast envelope; also faces the chromoplast stroma. FAO:0000008 ascocarp biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/FAO_0000008 A structure within, or at the surface of, which an ascus develops in Ascomycetes. GO:0031896 V2 vasopressin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031896 V2 vasopressin receptor ligand Interacting selectively and non-covalently with a V2 vasopressin receptor. GO:0031897 Tic complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031897 chloroplast inner membrane translocase complex The translocon of the inner envelope of chloroplasts, which facilitates the import of proteins across the chloroplast inner membrane. FAO:0000001 fungal structure biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/FAO_0000001 fungal structure ontology An anatomical structure that forms all or part of a fungus. GO:0090259 regulation of retinal ganglion cell axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090259 Any process that modulates the frequency, rate, or extent of retinal ganglion cell axon guidance, the process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues. GO:0016279 protein-lysine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016279 Reactome:R-HSA-8865237|Reactome:R-HSA-8932276|Reactome:R-HSA-8931858|Reactome:R-HSA-8932413|Reactome:R-HSA-8932221|Reactome:R-HSA-212263|Reactome:R-HSA-8932243|Reactome:R-HSA-8932275|Reactome:R-HSA-8931974 Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue in a protein substrate. GO:0090253 convergent extension involved in imaginal disc-derived wing morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090253 The morphogenetic process in which the wing epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to imaginal disc-derived wing morphogenesis. GO:0016275 [cytochrome c]-arginine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016275 RHEA:21872|MetaCyc:2.1.1.124-RXN|EC:2.1.1.124 S-adenosyl-L-methionine:cytochrome c-arginine omega-N-methyltransferasea|cytochrome c-arginine N-methyltransferase activity|S-adenosyl-L-methionine:cytochrome c-arginine nomega-methyltransferasea Catalysis of the reaction: S-adenosyl-L-methionine + (cytochrome c)-arginine = S-adenosyl-L-homocysteine + (cytochrome c)-N(omega)-methyl-arginine. GO:0031894 V1A vasopressin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031894 V1A vasopressin receptor ligand Interacting selectively and non-covalently with a V1A vasopressin receptor. GO:0016276 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016276 GO:0031895 V1B vasopressin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031895 V1B vasopressin receptor ligand Interacting selectively and non-covalently with a V1B vasopressin receptor. GO:0090254 cell elongation involved in imaginal disc-derived wing morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090254 The process in which a cell elongates and contributes to imaginal disc-derived wing morphogenesis. GO:0090251 protein localization involved in establishment of planar polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090251 protein localisation involved in establishment of planar polarity Any process in which a protein is transported to, and/or maintained in, a specific location in a cell that contributes to the establishment of planar polarity. GO:0016277 [myelin basic protein]-arginine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016277 myelin basic protein methylase activity|protein methylase I activity|myelin basic protein methylase I|S-adenosyl-L-methionine:myelin-basic-protein-arginine nomega-methyltransferase activity|myelin basic protein-arginine N-methyltransferase activity|S-adenosyl-L-methionine:myelin-basic-protein-arginine omega-N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + (myelin basic protein)-arginine = S-adenosyl-L-homocysteine + (myelin basic protein)-N(omega)-methyl-arginine. GO:0031892 type 2 vasoactive intestinal polypeptide receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031892 type 3 PACAP receptor binding|type 2 vasoactive intestinal polypeptide receptor ligand Interacting selectively and non-covalently with a type 2 vasoactive intestinal polypeptide receptor. GO:0090252 epithelium migration involved in imaginal disc-derived wing morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090252 The process in which the population of cells that make up a wing epithelium undergo directed movement and contribute to imaginal disc-derived morphogenesis. GO:0016278 lysine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016278 Reactome:R-HSA-3222237|Reactome:R-HSA-6805755|Reactome:R-HSA-6805730|Reactome:R-HSA-6805740 Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue. GO:0031893 vasopressin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031893 vasopressin receptor ligand Interacting selectively and non-covalently with a vasopressin receptor. GO:0031890 vasoactive intestinal polypeptide receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031890 vasoactive intestinal polypeptide receptor ligand|VIP receptor binding Interacting selectively and non-covalently with a vasoactive intestinal polypeptide receptor. CHEBI:4167 D-glucopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_4167 GO:0090257 regulation of muscle system process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090257 Any process that modulates the frequency, rate or extent of a muscle system process, a multicellular organismal process carried out by any of the organs or tissues in a muscle system. GO:0016271 obsolete tissue death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016271 OBSOLETE. A permanent cessation of all vital functions of a tissue. GO:0031891 type 1 vasoactive intestinal polypeptide receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031891 type 2 PACAP receptor binding|type 1 vasoactive intestinal polypeptide receptor ligand Interacting selectively and non-covalently with a type 1 vasoactive intestinal polypeptide receptor. GO:0016272 prefoldin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016272 Wikipedia:Prefoldin GIM complex A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics. GO:0090258 negative regulation of mitochondrial fission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090258 negative regulation of mitochondrial division Any process that decreases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments. GO:0016273 arginine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016273 Enables the transfer of a methyl group from S-adenosyl-L-methionine to an amino group of an arginine residue. GO:0090255 cell proliferation involved in imaginal disc-derived wing morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090255 The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to imaginal disc-derived wing morphogenesis. GO:0090256 regulation of cell proliferation involved in imaginal disc-derived wing morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090256 Any process that modulates the frequency, rate, or extent of the multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to imaginal disc-derived wing morphogenesis. GO:0016274 protein-arginine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016274 Reactome:R-HSA-5205822|Reactome:R-HSA-5205824|Reactome:R-HSA-8879123|Reactome:R-HSA-191790|Reactome:R-HSA-5229203|Reactome:R-HSA-8934735|Reactome:R-HSA-5205820|Reactome:R-HSA-5205867|Reactome:R-HSA-5218952|Reactome:R-HSA-5229010|Reactome:R-HSA-5661126|Reactome:R-HSA-5205798 PRMT activity Catalysis of the reaction: S-adenosyl-L-methionine + (protein)-arginine = S-adenosyl-L-homocysteine + (protein)-N-methyl-arginine. GO:0031889 urotensin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031889 urotensin receptor ligand Interacting selectively and non-covalently with a urotensin receptor. GO:0031887 lipid droplet transport along microtubule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031887 adiposome transport along microtubule|lipid particle transport along microtubule|lipid body transport along microtubule The directed movement of a lipid droplet along a microtubule, mediated by motor proteins. GO:0031888 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031888 GO:0031885 type 1 member 2 taste receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031885 type 1 member 2 taste receptor ligand Interacting selectively and non-covalently with a type 1 member 2 taste receptor. GO:0031886 type 1 member 3 taste receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031886 sweet taste receptor binding|type 1 member 3 taste receptor ligand Interacting selectively and non-covalently with a type 1 member 3 taste receptor. GO:0090228 positive regulation of red or far-red light signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090228 positive regulation of red or far-red light signalling pathway|positive regulation of phytochrome signaling pathway Any process that increases the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light. CHEBI:136105 (R)-PGA2-S-glutathione conjugate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136105 CHEBI:4139 D-galactopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_4139 GO:0090229 negative regulation of red or far-red light signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090229 negative regulation of red or far-red light signalling pathway|negative regulation of phytochrome signaling pathway Any process that decreases the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light. CHEBI:136106 (S)-PGA2-S-glutathione conjugate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136106 GO:0090226 regulation of microtubule nucleation by Ran protein signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090226 Any series of molecular signals in which a Ran GTPase relays one or more of the signals resulting in the modulation of the rate, frequency or extent of microtubule nucleation. GO:0090227 regulation of red or far-red light signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090227 regulation of red or far-red light signalling pathway|regulation of phytochrome signaling pathway Any process that modulates the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light. GO:0016246 RNA interference biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016246 Wikipedia:RNA_interference posttranscriptional gene silencing by siRNA|RNAi The process in which double-stranded RNAs silence cognate genes. Involves posttranscriptional gene inactivation ('silencing') both of transgenes or dsRNA introduced into a germline, and of the host gene(s) homologous to the transgenes or dsRNA. This silencing is triggered by the introduction of transgenes or double-stranded RNA (dsRNA), and can occur through a specific decrease in the level of mRNA, or by negative regulation of translation, of both host genes and transgenes. GO:0016247 channel regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016247 Modulates the activity of a channel. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. CHEBI:136107 8,9-epoxy-(5Z,11Z,14Z)-icosatrienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136107 GO:0016248 channel inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016248 Stops, prevents, or reduces the activity of a channel via direct interaction with the channel. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. GO:0016249 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016249 GO:0016242 negative regulation of macroautophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016242 inhibition of macroautophagy|negative regulation of starvation-induced autophagy|down-regulation of macroautophagy|downregulation of macroautophagy|down regulation of macroautophagy Any process that stops, prevents, or reduces the frequency, rate or extent of macroautophagy. GO:0031883 taste receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031883 taste receptor ligand Interacting selectively and non-covalently with a taste receptor. GO:0090220 chromosome localization to nuclear envelope involved in homologous chromosome segregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090220 chromosome localisation to nuclear envelope involved in homologous chromosome segregation The directed movement of a chromosome to the nuclear envelope that contributes to homologous chromosome segregation and precedes synapsis. GO:0016243 regulation of autophagosome size biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016243 regulation of autophagic vacuole size Any process that modulates the size of the autophagosome. GO:0031884 type 1 member 1 taste receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031884 type 1 member 1 taste receptor ligand Interacting selectively and non-covalently with a type 1 member 1 taste receptor. GO:0090221 mitotic spindle-templated microtubule nucleation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090221 The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from within the mitotic spindle. GO:0031881 type 4 somatostatin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031881 type 4 somatostatin receptor ligand Interacting selectively and non-covalently with a type 4 somatostatin receptor. GO:0016244 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016244 GO:0031882 type 5 somatostatin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031882 type 5 somatostatin receptor ligand Interacting selectively and non-covalently with a type 5 somatostatin receptor. GO:0016245 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016245 GO:0090224 regulation of spindle organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090224 regulation of spindle organisation Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle. GO:0031880 type 3 somatostatin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031880 type 3 somatostatin receptor ligand Interacting selectively and non-covalently with a type 3 somatostatin receptor. GO:0090225 regulation of spindle density biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090225 Any process that modulates the number of microtubules in a given region of the spindle. GO:0090222 centrosome-templated microtubule nucleation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090222 The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from the centrosome. GO:0016240 autophagosome membrane docking biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016240 autophagic vacuole docking The initial attachment of an autophagosome membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane. Docking requires only that the two membranes come close enough for these proteins to interact and adhere. GO:0090223 chromatin-templated microtubule nucleation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090223 The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from chromatin. GO:0016241 regulation of macroautophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016241 regulation of starvation-induced autophagy Any process that modulates the frequency, rate or extent of macroautophagy. GO:0031878 type 1 somatostatin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031878 type 1 somatostatin receptor ligand Interacting selectively and non-covalently with a type 1 somatostatin receptor. GO:0031879 type 2 somatostatin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031879 type 2 somatostatin receptor ligand Interacting selectively and non-covalently with a type 2 somatostatin receptor. GO:0031876 secretin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031876 secretin receptor ligand Interacting selectively and non-covalently with a secretin receptor. GO:0031877 somatostatin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031877 somatostatin receptor ligand Interacting selectively and non-covalently with a somatostatin receptor. GO:0031874 type 3 proteinase activated receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031874 type 3 proteinase activated receptor ligand Interacting selectively and non-covalently with a type 3 proteinase activated receptor. GO:0031875 type 4 proteinase activated receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031875 type 4 proteinase activated receptor ligand Interacting selectively and non-covalently with a type 4 proteinase activated receptor. GO:0090239 regulation of histone H4 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090239 Any process that modulates the rate, frequency, or extent of histone H4 acetylation, the modification of histone H4 by the addition of an acetyl group. CHEBI:136117 14,15-epoxy-(5Z,8Z,11Z)-icosatrienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136117 GO:0090237 regulation of arachidonic acid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090237 Any process that modulates the rate, frequency, or extent of arachidonic acid secretion, the controlled release of arachidonic acid from a cell or a tissue. GO:0090238 positive regulation of arachidonic acid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090238 Any process that increases the rate, frequency, or extent of arachidonic acid secretion, the controlled release of arachidonic acid from a cell or a tissue. CHEBI:136115 11,12-epoxy-(5Z,8Z,14Z)-icosatrienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136115 GO:0016257 N-glycan processing to secreted and cell-surface N-glycans biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016257 The modification of high-mannose (Man9-Asn) N-glycans by mannosyl-oligosaccharide 1,2-alpha-mannosidase. This may result in Man8GlcNAc2-Asn N-glycans (which in yeast may be subsequently modified by the addition of further mannose residues) or Man5GlcNAc2-Asn N-glycans that are substrates for further diversification in the Golgi apparatus. GO:0016258 N-glycan diversification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016258 The generation, in the Golgi apparatus, of side chain diversity from high mannose Man5GlcNAc2-Asn N-glycans by specific glycosyltransferases and glycosidases. GO:0016259 selenocysteine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016259 selenocysteine metabolism The chemical reactions and pathways involving selenocysteine, an essential component of glutathione peroxidase and some other proteins. CHEBI:136118 (4Z,7Z,10Z,13Z,15E,17S)-17-hydroperoxydocosapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136118 GO:0031872 type 1 proteinase activated receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031872 thrombin receptor binding|type 1 proteinase activated receptor ligand Interacting selectively and non-covalently with a type 1 proteinase activated receptor. CHEBI:4141 D-galactopyranose 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_4141 GO:0090231 regulation of spindle checkpoint biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0090231 Any process that modulates the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle. GO:0016253 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016253 GO:0090232 positive regulation of spindle checkpoint biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0090232 spindle checkpoint activation Any process that increases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle. GO:0016254 preassembly of GPI anchor in ER membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016254 preassembly of GPI anchor in endoplasmic reticulum membrane The stepwise addition of the components of the GPI anchor on to phosphatidylinositol lipids in the endoplasmic reticulum membrane. GO:0031873 type 2 proteinase activated receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031873 type 2 proteinase activated receptor ligand Interacting selectively and non-covalently with a type 2 proteinase activated receptor. GO:0031870 thromboxane A2 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031870 prostanoid TP receptor binding|thromboxane A2 receptor ligand Interacting selectively and non-covalently with a thromboxane A2 receptor. GO:0016255 attachment of GPI anchor to protein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016255 A transamidation reaction that results in the cleavage of the polypeptide chain and the concomitant transfer of the GPI anchor to the newly formed carboxy-terminal amino acid of the anchored protein. The cleaved C-terminal contains the C-terminal GPI signal sequence of the newly synthesized polypeptide chain. GO:0031871 proteinase activated receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031871 proteinase activated receptor ligand Interacting selectively and non-covalently with a proteinase activated receptor. GO:0090230 regulation of centromere complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090230 centromere licensing Any process that modulates the rate, frequency, or extent of centromere complex assembly, the aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex. GO:0016256 N-glycan processing to lysosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016256 The modification of high-mannose N-glycans by UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase and the subsequent removal of the N-acetylglucosamine residues yielding mannose-6-P that occurs in the ER-Golgi apparatus to N-glycans destined for the lysosome. GO:0090235 regulation of metaphase plate congression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090235 regulation of chromosome congression Any process that modulates the rate, frequency, or extent of metaphase plate congression, the alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the spindle. CHEBI:136112 (S)-PGJ2-S-glutathione conjugate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136112 GO:0016250 N-sulfoglucosamine sulfohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016250 MetaCyc:N-SULFOGLUCOSAMINE-SULFOHYDROLASE-RXN|Reactome:R-HSA-2090043|Reactome:R-HSA-2263444|Reactome:R-HSA-1678708|RHEA:17881|EC:3.10.1.1|Reactome:R-HSA-9036050 N-sulfo-D-glucosamine sulfohydrolase activity|sulphamidase activity|N-sulphoglucosamine sulphohydrolase activity|heparin sulfamidase activity|sulfoglucosamine sulfamidase activity|2-desoxy-D-glucoside-2-sulphamate sulphohydrolase (sulphamate sulphohydrolase) Catalysis of the reaction: N-sulfo-D-glucosamine + H2O = D-glucosamine + sulfate. GO:0090236 obsolete regulation of transcription from RNA polymerase II promoter involved in somitogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090236 OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo. CHEBI:136113 (4Z,7Z,10Z,13Z,15E,17S,19Z)-17-hydroperoxydocosahexaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136113 GO:0016251 RNA polymerase II general transcription initiation factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016251 RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity|general RNA polymerase II transcription factor activity|GTF2 activity|RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly|basal RNA polymerase II transcription factor activity|sequence-specific core promoter binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly|transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly|transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding A general transcription initiation factor activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase II. The general transcription factors for RNA polymerase II include TFIIB, TFIID, TFIIE, TFIIF, TFIIH and TATA-binding protein (TBP). In most species, RNA polymerase II transcribes all messenger RNAs (mRNAs), most untranslated regulatory RNAs, the majority of the snoRNAs, four of the five snRNAs (U1, U2, U4, and U5), and other small noncoding RNAs. For some small RNAs there is variability between species as to whether it is transcribed by RNA polymerase II or RNA polymerase III. However there are also rare exceptions, such as Trypanosoma brucei, where RNA polymerase I transcribes certain mRNAs in addition to its normal role in rRNA transcription. CHEBI:136110 (R)-PGJ2-S-glutathione conjugate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136110 GO:0090233 negative regulation of spindle checkpoint biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0090233 spindle checkpoint silencing Any process that decreases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle. GO:0090234 regulation of kinetochore assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090234 regulation of chromosome-kinetochore attachment Any process that modulates the rate, frequency, or extent of kinetochore assembly, the aggregation, arrangement and bonding together of a set of components to form the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules. GO:0016252 obsolete nonspecific RNA polymerase II transcription factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016252 nonspecific RNA polymerase II transcription factor activity OBSOLETE. Any function that supports transcription of genes by RNA polymerase II, and is not specific to a particular gene or gene set. UBERON_CORE:filtered_through filtered through biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/uberon/core#filtered_through filtered_through Relationship between a fluid and a material entity, where the fluid is the output of a realization of a filtration role that inheres in the material entity. CHEBI:4194 D-hexose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_4194 CHEBI:4195 D-hexose 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_4195 UBERON:0017163 skin bony tubercle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0017163 bony tubercle|bony tubercles A bony structure embedded in skin, roughly equivalent to osteoderms. NCBITaxon:43845 Drosophilinae organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_43845 CHEBI:4178 D-glucuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_4178 CHEBI:4177 D-glucosylsphingosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_4177 PATO:0001408 ciliatedness biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PATO_0001408 A cellular quality inhering in a bearer by virtue of the bearer's having thin, tail-like projections extending outwards from the cell body. SO:0100021 polypeptide_conserved_region biolink:SequenceFeature go-plus biosapiens http://purl.obolibrary.org/obo/SO_0100021 polypeptide conserved region A subsection of sequence with biological interest that is conserved in different proteins. They may or may not have functional or structural significance within the proteins in which they are found. CHEBI:81467 7alpha-hydroxypregnenolone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_81467 PATO:0001406 binucleate biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PATO_0001406 A nucleate quality inhering in a bearer by virtue of the bearer's having two nuclei. PATO:0001407 mononucleate biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PATO_0001407 A nucleate quality inhering in a bearer by virtue of the bearer's having one nucleus. CHEBI:81463 dTDP-alpha-D-forosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_81463 PATO:0001404 nucleate quality biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PATO_0001404 A cellular quality inhering in a bearer by virtue of bearer's number of nuclei. PATO:0001405 anucleate biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PATO_0001405 A nucleate quality inhering in a bearer by virtue of the bearer's having no nucleus. CHEBI:81461 dTDP-4-dehydro-2,3,6-trideoxy-alpha-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_81461 CHEBI:81462 dTDP-4-amino-2,3,4,6-tetradeoxy-alpha-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_81462 CHEBI:4188 D-glycero-D-manno-heptose 1,7-bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_4188 CHEBI:81474 N-Acetyl-alpha-D-hexosamine 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_81474 CHEBI:81471 7alpha-hydroxydehydroepiandrosterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_81471 CHEBI:81485 osthenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_81485 SO:0100001 biochemical_region_of_peptide biolink:SequenceFeature go-plus biosapiens http://purl.obolibrary.org/obo/SO_0100001 biochemical region of peptide|biochemical motif|biochemical_region A region of a peptide that is involved in a biochemical function. CHEBI:81481 11beta-hydroxytestosterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_81481 CHEBI:136183 N-jasmonyl-L-alpha-amino acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136183 CHEBI:136184 jasmonic acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136184 CHEBI:175763 2-trans,6-trans-farnesyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_175763 GO:0006825 copper ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006825 The directed movement of copper (Cu) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0006826 iron ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006826 iron transport|ferric ion transport|iron ion import|ferric ion import|ferrous iron transport|ferrous ion transport|ferric iron transport|ferric iron import|ferric iron uptake The directed movement of iron (Fe) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0006823 obsolete heavy metal ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006823 heavy metal ion transport OBSOLETE. The directed movement of heavy metal ions into, out of or within a cell, or between cells. Heavy metals are those that can form a coordination bond with a protein, as opposed to an alkali or alkaline-earth metal that can only form an ionic bond; this definition includes the following biologically relevant heavy metals: Cd, Co, Cu, Fe, Hg, Mn, Mo, Ni, V, W, Zn. GO:0006824 cobalt ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006824 cobalt transport The directed movement of cobalt (Co) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0006821 chloride transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006821 The directed movement of chloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0006822 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006822 GO:0006820 anion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006820 The directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:32425 (11Z)-icos-11-enoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32425 CHEBI:32426 gondoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32426 GO:0006829 zinc ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006829 zinc II ion transport|zinc transport The directed movement of zinc (Zn II) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0006827 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006827 GO:0006828 manganese ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006828 The directed movement of manganese (Mn) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0006836 neurotransmitter transport biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0006836 sodium:neurotransmitter transport The directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell. GO:0006837 serotonin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006837 The directed movement of serotonin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems. GO:0006834 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006834 GO:0006835 dicarboxylic acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006835 sodium:dicarboxylate transport The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0006832 obsolete small molecule transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006832 small molecule transport OBSOLETE. (Was not defined before being made obsolete). GO:0006833 water transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006833 The directed movement of water (H2O) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0006830 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006830 GO:0006831 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006831 CHEBI:32436 D-alaninium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32436 CHEBI:32437 D-alanyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32437 CHEBI:32439 alaninate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32439 CHEBI:32431 L-alaninate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32431 CHEBI:32432 L-alaninium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32432 CHEBI:32433 L-alanyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32433 CHEBI:32435 D-alaninate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32435 GO:0006838 obsolete allantoin/allantoate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006838 allantoin/allantoate transport OBSOLETE. (Was not defined before being made obsolete). GO:0006839 mitochondrial transport biolink:BiologicalProcess go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0006839 mitochondrial aspartate/glutamate transport|mitochondrial sodium/calcium ion exchange|mitochondrial alpha-ketoglutarate/malate transport Transport of substances into, out of or within a mitochondrion. GO:0006803 obsolete glutathione conjugation reaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006803 glutathione conjugation reaction OBSOLETE. (Was not defined before being made obsolete). GO:0006804 obsolete peroxidase reaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006804 peroxidase reaction OBSOLETE. (Was not defined before being made obsolete). GO:0006801 superoxide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006801 superoxide free radical metabolism|oxygen free radical metabolic process|oxygen free radical metabolism|superoxide metabolism|superoxide free radical metabolic process The chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species. GO:0006802 obsolete catalase reaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006802 hydroperoxidase reaction|catalase reaction OBSOLETE. The processes involved in the induction or activation of catalase, an enzyme that catalyzes the conversion of H2O2 into H2O. GO:0006800 obsolete oxygen and reactive oxygen species metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006800 oxygen and ROS metabolic process|oxygen and reactive oxygen species metabolism|oxygen and reactive oxygen intermediate metabolism|oxygen and AOS metabolism|oxygen and reactive oxidative species metabolism|oxygen and ROI metabolism|oxygen and reactive oxygen species metabolic process|oxygen and ROS metabolism|oxygen and active oxygen species metabolism OBSOLETE. The chemical reactions and pathways involving dioxygen (O2), or any of the reactive oxygen species, e.g. superoxide anions (O2-), hydrogen peroxide (H2O2), and hydroxyl radicals (-OH). CHEBI:32408 parinaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32408 CHEBI:32409 (9Z,11E,13E,15Z)-octadecatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32409 CHEBI:32402 catecholate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32402 GO:0006809 nitric oxide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006809 nitric oxide anabolism|nitric oxide synthesis|nitric oxide formation|nitric oxide biosynthesis The chemical reactions and pathways resulting in the formation of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water. GO:0006807 nitrogen compound metabolic process biolink:BiologicalProcess go-plus goslim_pir|goslim_metagenomics http://purl.obolibrary.org/obo/GO_0006807 nitrogen compound metabolism The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen. GO:0006808 regulation of nitrogen utilization biolink:BiologicalProcess go-plus goslim_metagenomics http://purl.obolibrary.org/obo/GO_0006808 Any process that modulates the frequency, rate or extent of nitrogen utilization. GO:0006805 xenobiotic metabolic process biolink:BiologicalProcess go-plus goslim_chembl|goslim_pir http://purl.obolibrary.org/obo/GO_0006805 Wikipedia:Xenobiotic_metabolism xenobiotic metabolism The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide. GO:0006806 obsolete insecticide resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006806 insecticide resistance OBSOLETE. (Was not defined before being made obsolete). GO:0006814 sodium ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006814 sodium channel auxiliary protein activity|sodium transport|sodium:calcium exchange|sodium/potassium transport|mitochondrial sodium/calcium ion exchange|sodium:solute transport The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0006815 obsolete sodium/potassium transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006815 sodium/potassium transport OBSOLETE. (Was not defined before being made obsolete). GO:0006812 cation transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006812 di-, tri-valent inorganic cation transport|trivalent inorganic cation transport The directed movement of cations, atoms or small molecules with a net positive charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0006813 potassium ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006813 sodium/potassium transport|potassium transport|potassium ion conductance|cellular potassium ion transport|K+ conductance|potassium conductance|low voltage-gated potassium channel auxiliary protein activity|low voltage-dependent potassium channel auxiliary protein activity The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0006810 transport biolink:BiologicalProcess go-plus goslim_generic|goslim_chembl|goslim_candida|gocheck_do_not_annotate|goslim_plant|goslim_pir|goslim_metagenomics|goslim_aspergillus http://purl.obolibrary.org/obo/GO_0006810 single-organism transport|solute:solute exchange|small molecule transport The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter, pore or motor protein. GO:0006811 ion transport biolink:BiologicalProcess go-plus goslim_yeast|goslim_pir|goslim_drosophila http://purl.obolibrary.org/obo/GO_0006811 The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:32414 cis-parinarate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32414 GO:0006818 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006818 GO:0006819 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006819 GO:0006816 calcium ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006816 sodium:calcium exchange|mitochondrial sodium/calcium ion exchange|calcium transport The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0006817 phosphate ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006817 phosphate transport The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:81405 N-Acetyldemethylphosphinothricin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_81405 CHEBI:81403 2-phosphinomethylmalic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_81403 GO:0031869 prostacyclin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031869 prostacyclin receptor ligand|prostanoid IP receptor binding Interacting selectively and non-covalently with a prostacyclin receptor. GO:0031867 EP4 subtype prostaglandin E2 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031867 prostanoid EP4 receptor binding|EP4 subtype prostaglandin E2 receptor ligand Interacting selectively and non-covalently with an EP4 subtype prostaglandin E2 receptor. GO:0031868 prostaglandin F2-alpha receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031868 prostanoid FP receptor binding|prostaglandin F2-alpha receptor ligand Interacting selectively and non-covalently with a prostaglandin F2-alpha receptor. GO:0031865 EP2 subtype prostaglandin E2 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031865 prostanoid EP2 receptor binding|EP2 subtype prostaglandin E2 receptor ligand Interacting selectively and non-covalently with an EP2 subtype prostaglandin E2 receptor. GO:0090161 Golgi ribbon formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090161 The formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae. GO:0031866 EP3 subtype prostaglandin E2 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031866 prostanoid EP3 receptor binding|EP3 subtype prostaglandin E2 receptor ligand Interacting selectively and non-covalently with an EP3 subtype prostaglandin E2 receptor. GO:0090162 establishment of epithelial cell polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090162 The specification and formation of anisotropic intracellular organization of an epithelial cell. GO:0031863 prostaglandin D2 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031863 prostanoid DP receptor binding|prostaglandin D2 receptor ligand Interacting selectively and non-covalently with a prostaglandin D2 receptor. GO:0031864 EP1 subtype prostaglandin E2 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031864 prostanoid EP1 receptor binding|EP1 subtype prostaglandin E2 receptor ligand Interacting selectively and non-covalently with an EP1 subtype prostaglandin E2 receptor. GO:0090160 Golgi to lysosome transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090160 The directed movement of substances from the Golgi to lysosomes. UBERON:0007806 connecting stalk biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007806 A bridge of mesoderm connecting the caudal end of the young embryo with the trophoblastic tissues; the precursor of the umbilical cord. UBERON:0007807 connecting stalk vasculature biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007807 connecting stalk blood vessels|connecting stalk blood vessel|vasculature of connecting stalk A vasculature that is part of a connecting stalk. UBERON:0007808 adipose tissue of abdominal region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007808 abdominal fat|abdominal adipose tissue|intra-abdominal fat Adipose tissue that is located in the abdominal region. This includes any subcutaneous fat, visceral fat or encapsulated adipose tissue depots. GO:0016228 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016228 GO:0016229 steroid dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016229 Catalysis of an oxidation-reduction (redox) reaction in which one substrate is a sterol derivative. UBERON:0007811 craniocervical region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007811 head or neck|cephalic part of animal|cephalic region|cephalic area|head and neck The anteriormost subdivision of the body that includes the head, jaws, pharyngeal region and the neck (if present). In vertebrates this is the subdivision that includes the cervical vertebrae. GO:0016224 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016224 UBERON:0007812 post-anal tail biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007812 postanal tail|muscular postanal tail|post-vent region|post-anal fin tail A tail that extends from the posterior tip of the organism to the anus, contains muscle and skeleton. GO:0016225 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016225 GO:0016226 iron-sulfur cluster assembly biolink:BiologicalProcess go-plus goslim_metagenomics|goslim_pombe http://purl.obolibrary.org/obo/GO_0016226 iron-sulphur cluster assembly|iron-sulfur cluster biosynthesis The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster. GO:0016227 obsolete tRNA sulfurtransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016227 transfer RNA sulfurtransferase activity|tRNA sulfurtransferase activity|transfer ribonucleate sulfurtransferase activity|L-cysteine:tRNA sulfurtransferase activity|ribonucleate sulfurtransferase activity|transfer RNA thiolase activity|RNA sulfurtransferase activity|tRNA sulphurtransferase activity OBSOLETE. Catalysis of the reaction: L-cysteine + 'activated' tRNA = L-serine + tRNA containing a thionucleotide. GO:0090165 regulation of secretion by asymmetric Golgi ribbon formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090165 The asymmetric formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae that modulates the controlled release of a substance from a polarized epithelial cell. GO:0031861 prolactin-releasing peptide receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031861 prolactin-releasing peptide receptor ligand Interacting selectively and non-covalently with a prolactin-releasing peptide receptor. GO:0016220 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016220 GO:0090166 Golgi disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090166 A cellular process that results in the breakdown of a Golgi apparatus that contributes to Golgi inheritance. GO:0031862 prostanoid receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031862 prostanoid receptor ligand Interacting selectively and non-covalently with a prostanoid receptor. GO:0090163 establishment of epithelial cell planar polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090163 The specification and formation of the polarity of an epithelial cell along the plane of the epithelial tissue. GO:0016222 procollagen-proline 4-dioxygenase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016222 prolyl 4-hydroxylase complex|procollagen-proline, 2-oxoglutarate-4-dioxygenase complex A protein complex that catalyzes the formation of procollagen trans-4-hydroxy-L-proline and succinate from procollagen L-proline and 2-oxoglutarate, requiring Fe2+ and ascorbate. Contains two alpha subunits that contribute to most parts of the catalytic sites, and two beta subunits that are identical to protein-disulfide isomerase. GO:0090164 asymmetric Golgi ribbon formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090164 The asymmetric formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae that contributes to the establishment of epithelial cell polarity. GO:0016223 beta-alanine-pyruvate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016223 MetaCyc:2.6.1.18-RXN|RHEA:14077|Reactome:R-HSA-909776|EC:2.6.1.18 omega-amino acid--pyruvate aminotransferase activity|beta-alanine--pyruvate aminotransferase activity|beta-alanine-pyruvate aminotransferase activity|L-alanine:3-oxopropanoate aminotransferase activity|beta-alanine-alpha-alanine transaminase activity Catalysis of the reaction: L-alanine + 2-oxopropanoate = pyruvate + beta-alanine. GO:0031860 telomeric 3' overhang formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031860 telomere end processing|telomere 3'-end processing The formation of the single stranded telomeric 3' overhang, a conserved feature that ranges in length from 12 nt in budding yeast to approximately 500 nt in humans. GO:0090169 regulation of spindle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090169 regulation of spindle formation Any process that modulates the rate, frequency or extent of spindle assembly. Spindle assembly is the aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart. GO:0090167 Golgi distribution to daughter cells biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090167 Any process in which disassembled Golgi vesicles are localized into daughter cells upon cell division. GO:0090168 Golgi reassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090168 The reformation of the Golgi following its breakdown and partitioning contributing to Golgi inheritance. GO:0031858 pituitary adenylate cyclase-activating polypeptide receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031858 PACAP receptor binding|pituitary adenylate cyclase-activating peptide receptor ligand|pituitary adenylate cyclase activating peptide receptor binding Interacting selectively and non-covalently with a pituitary adenylate cyclase-activating polypeptide receptor. GO:0031859 platelet activating factor receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031859 platelet activating factor receptor ligand Interacting selectively and non-covalently with a platelet activating factor receptor. GO:0031856 parathyroid hormone receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031856 parathyroid hormone receptor ligand Interacting selectively and non-covalently with a parathyroid hormone receptor. GO:0031857 type 1 parathyroid hormone receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031857 type 1 parathyroid hormone receptor ligand Interacting selectively and non-covalently with a type 1 parathyroid hormone receptor. GO:0090172 microtubule cytoskeleton organization involved in homologous chromosome segregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090172 microtubule cytoskeleton organisation involved in homologous chromosome segregation|microtubule organization involved in chromosome pairing A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins that contributes to chromosomal pairing and precedes synapsis. GO:0031854 orexigenic neuropeptide QRFP receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031854 orexigenic neuropeptide QRFP receptor ligand Interacting selectively and non-covalently with an orexigenic neuropeptide QRFP receptor. GO:0090173 regulation of synaptonemal complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090173 Any process that modulates the frequency, rate or extent of synaptonemal complex assembly. Synaptonemal complex assembly is the cell cycle process in which the synaptonemal complex, a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination, is formed. GO:0031855 oxytocin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031855 oxytocin receptor ligand Interacting selectively and non-covalently with an oxytocin receptor. GO:0031852 mu-type opioid receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031852 morphine receptor binding|mu-type opioid receptor ligand Interacting selectively and non-covalently with a mu-type opioid receptor. GO:0090170 regulation of Golgi inheritance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090170 Any process that modulates the rate, frequency or extent of Golgi inheritance. Golgi inheritance is the partitioning of Golgi apparatus between daughter cells at cell division. GO:0031853 nociceptin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031853 nociceptin receptor ligand Interacting selectively and non-covalently with a nociceptin receptor. GO:0090171 chondrocyte morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090171 The process in which the structures of a chondrocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a chondrocyte. GO:0016239 positive regulation of macroautophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016239 activation of macroautophagy|up regulation of macroautophagy|upregulation of macroautophagy|positive regulation of starvation-induced autophagy|stimulation of macroautophagy|up-regulation of macroautophagy Any process, such as recognition of nutrient depletion, that activates or increases the rate of macroautophagy to bring cytosolic macromolecules to the vacuole/lysosome for degradation. CHEBI:136219 lysophosphatidylglycerol 18:1/0:0 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136219 GO:0016235 aggresome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016235 Wikipedia:Aggresome An inclusion body formed by dynein-dependent retrograde transport of an aggregated protein on microtubules. GO:0016236 macroautophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016236 autophagy The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure. Autophagosomes then fuse with a lysosome (or vacuole) releasing single-membrane-bounded autophagic bodies that are then degraded within the lysosome (or vacuole). Some types of macroautophagy, e.g. pexophagy, mitophagy, involve selective targeting of the targets to be degraded. GO:0016237 lysosomal microautophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016237 The transfer of cytosolic components into the lysosomal compartment by direct invagination of the lysosomal membrane without prior sequestration into an autophagosome. The engulfing membranes fuse, resulting in the lysosomal delivery of the cargo wrapped in a single membrane derived from the invaginated lysosomal membrane. In S. cerevisiae, the vacuole is the lysosomal compartment. CHEBI:136218 lysophosphatidylglycerol 18:1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136218 GO:0016238 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016238 GO:0031850 delta-type opioid receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031850 enkephalin receptor binding|delta-type opioid receptor ligand Interacting selectively and non-covalently with a delta-type opioid receptor. GO:0090176 microtubule cytoskeleton organization involved in establishment of planar polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090176 microtubule cytoskeleton organisation involved in establishment of planar polarity A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins and contributes to the establishment of planar polarity. GO:0016231 beta-N-acetylglucosaminidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016231 Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-beta-D-glucosaminides. GO:0016232 HNK-1 sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016232 Reactome:R-HSA-6786048 HNK-1 sulphotransferase activity Catalysis of the synthesis of the HKK-1 carbohydrate epitope; adds a sulfate group to a precursor, GlcA-beta-(1->3)-Gal-beta-(1->4)-GlcNAc-beta-(1->R), forming sulfo-3GlcA-beta-(1->3)-Gal-beta-(1->4)-GlcNAc-beta-(1->R). GO:0031851 kappa-type opioid receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031851 kappa-type opioid receptor ligand|dynorphin receptor binding Interacting selectively and non-covalently with a kappa-type opioid receptor. GO:0090177 establishment of planar polarity involved in neural tube closure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090177 Coordinated organization of groups of cells in the plane of an epithelium that contributes to the closure of the neural tube. GO:0090174 organelle membrane fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090174 The joining of two lipid bilayers to form a single organelle membrane. GO:0016233 telomere capping biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016233 telomere end protection A process in which telomeres are protected from degradation and fusion, thereby ensuring chromosome stability by protecting the ends from both degradation and from being recognized as damaged DNA. May be mediated by specific single- or double-stranded telomeric DNA binding proteins. GO:0090175 regulation of establishment of planar polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090175 Any process that modulates the rate, frequency or extent of the establishment of planar polarity, the coordinated organization of groups of cells in a tissue, such that they all orient to similar coordinates. GO:0016234 inclusion body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0016234 NIF_Subcellular:sao120573470|Wikipedia:Inclusion_bodies neuronal cytoplasmic inclusion|cellular inclusion A discrete intracellular part formed of aggregated molecules such as proteins or other biopolymers. GO:0090178 regulation of establishment of planar polarity involved in neural tube closure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090178 Any process that modulates the rate, frequency, or extent of the establishment of planar polarity involved in neural tube closure, the coordinated organization of groups of cells in the plane of an epithelium that contributes to the closure of the neural tube. GO:0090179 planar cell polarity pathway involved in neural tube closure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090179 The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors that modulates the establishment of planar polarity contributing to neural tube closure. GO:0016230 sphingomyelin phosphodiesterase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016230 neutral sphingomyelinase activator Increases the activity of the enzyme sphingomyelin phosphodiesterase. GO:0031847 type 1 neurotensin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031847 type 1 neurotensin receptor ligand Interacting selectively and non-covalently with a type 1 neurotensin receptor. GO:0031848 protection from non-homologous end joining at telomere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031848 protection from NHEJ-mediated telomere fusion A process that prevents non-homologous end joining at telomere, thereby ensuring that telomeres do not fuse. GO:0006889 obsolete regulation of calcium in ER biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006889 regulation of calcium in ER OBSOLETE. Any process that modulates the concentration of calcium in the endoplasmic reticulum. GO:0031845 type 5 neuropeptide Y receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031845 type 5 neuropeptide Y receptor ligand Interacting selectively and non-covalently with a type 5 neuropeptide Y receptor. GO:0031846 neurotensin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031846 neurotensin receptor ligand Interacting selectively and non-covalently with a neurotensin receptor. GO:0006887 exocytosis biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0006887 Wikipedia:Exocytosis nonselective vesicle exocytosis|vesicle exocytosis A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell. GO:0031843 type 2 neuropeptide Y receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031843 type 2 neuropeptide Y receptor ligand Interacting selectively and non-covalently with a type 2 neuropeptide Y receptor. GO:0090140 regulation of mitochondrial fission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090140 regulation of mitochondrial division Any process that modulates the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments. GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006888 anterograde (ER to Golgi) transport|rough endoplasmic reticulum to cis-Golgi transport|rough ER to cis-Golgi vesicle-mediated transport|ER to Golgi transport|endoplasmic reticulum to Golgi vesicle-mediated transport|anterograde transport, ER to Golgi|endoplasmic reticulum to Golgi transport|ER to Golgi vesicle-mediated transport|anterograde vesicle-mediated transport, endoplasmic reticulum to Golgi|rough ER to cis-Golgi transport|rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport|anterograde vesicle-mediated transport, ER to Golgi|anterograde transport, endoplasmic reticulum to Golgi The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi. GO:0031844 type 4 neuropeptide Y receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031844 type 4 neuropeptide Y receptor ligand|pancreatic polypeptide receptor binding Interacting selectively and non-covalently with a type 4 neuropeptide Y receptor. GO:0006885 regulation of pH biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006885 hydrogen ion homeostasis Any process involved in the maintenance of an internal equilibrium of hydrogen ions, thereby modulating the internal pH, within an organism or cell. GO:0031841 neuropeptide Y receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031841 NPY receptor binding|neuropeptide Y receptor ligand Interacting selectively and non-covalently with a neuropeptide Y receptor. GO:0031842 type 1 neuropeptide Y receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031842 type 1 neuropeptide Y receptor ligand Interacting selectively and non-covalently with a type 1 neuropeptide Y receptor. GO:0006886 intracellular protein transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006886 copper-induced intracellular protein transport The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell. GO:0006883 cellular sodium ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006883 Any process involved in the maintenance of an internal steady state of sodium ions at the level of a cell. GO:0006884 cell volume homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006884 regulation of cell volume Any process involved in maintaining the steady state of a cell's volume. The cell's volume refers to the three-dimensional space occupied by a cell. GO:0006881 extracellular sequestering of iron ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006881 extracellular iron ion retention|extracellular iron ion storage|extracellular retention of iron ion|extracellular iron ion sequestering|extracellular storage of iron ion|extracellular iron ion sequestration|extracellular sequestration of iron ion The process of binding or confining iron ions in an extracellular area such that they are separated from other components of a biological system. GO:0006882 cellular zinc ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006882 zinc homeostasis Any process involved in the maintenance of an internal steady state of zinc ions at the level of a cell. GO:0006880 intracellular sequestering of iron ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006880 intracellular iron ion storage|intracellular retention of iron ion|intracellular iron ion sequestering|intracellular storage of iron ion|intracellular iron ion sequestration|intracellular sequestration of iron ion|intracellular iron ion retention The process of binding or confining iron ions in an intracellular area such that they are separated from other components of a biological system. GO:0031849 olfactory receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031849 olfactory receptor ligand Interacting selectively and non-covalently with an olfactory receptor. GO:0016206 catechol O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016206 Reactome:R-HSA-175983|EC:2.1.1.6|Reactome:R-HSA-8955010|MetaCyc:CATECHOL-O-METHYLTRANSFERASE-RXN S-adenosyl-L-methionine:catechol O-methyltransferase activity|S-COMT (soluble form of catechol-O-methyltransferase)|COMT II|MB-COMT (membrane-bound form of catechol-O-methyltransferase)|catecholamine O-methyltransferase activity|COMT I|catechol methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + a catechol = S-adenosyl-L-homocysteine + a guaiacol. CHEBI:32483 glutamic acid residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32483 GO:0016207 4-coumarate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016207 KEGG_REACTION:R01616|MetaCyc:4-COUMARATE--COA-LIGASE-RXN|EC:6.2.1.12|RHEA:19641 sinapoyl coenzyme A synthetase activity|p-hydroxycinnamoyl coenzyme A synthetase activity|4-coumarate-CoA synthetase activity|4-coumaroyl-CoA synthase activity|p-coumaryl-CoA synthetase activity|feruloyl CoA ligase activity|p-coumaryl-CoA ligase activity|hydroxycinnamate:CoA ligase activity|4-coumaryl-CoA synthetase activity|p-coumaryl coenzyme A synthetase activity|p-coumaroyl CoA ligase activity|4-coumarate:coenzyme A ligase activity|4-coumarate:CoA ligase activity|4-coumarate:CoA ligase (AMP-forming)|4-coumaroyl-CoA synthetase activity|p-hydroxycinnamic acid:CoA ligase activity|4CL|caffeolyl coenzyme A synthetase activity|feruloyl coenzyme A synthetase activity|hydroxycinnamoyl CoA synthetase activity Catalysis of the reaction: ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA. CHEBI:32484 glutamate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32484 GO:0090149 mitochondrial membrane fission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090149 mitochondrial membrane scission|membrane fission involved in mitochondrial fission A process that is carried out at the cellular level which results in the separation of a single continuous mitochondrial membrane into two membranes and contributes to mitochondrial fission. GO:0016208 AMP binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016208 Interacting selectively and non-covalently with AMP, adenosine monophosphate. GO:0016209 antioxidant activity biolink:MolecularActivity go-plus goslim_pir|goslim_metagenomics http://purl.obolibrary.org/obo/GO_0016209 Inhibition of the reactions brought about by dioxygen (O2) or peroxides. Usually the antioxidant is effective because it can itself be more easily oxidized than the substance protected. The term is often applied to components that can trap free radicals, thereby breaking the chain reaction that normally leads to extensive biological damage. CHEBI:32486 L-phenylalaninate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32486 CHEBI:32487 L-phenylalaninium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32487 GO:0016202 regulation of striated muscle tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016202 Any process that modulates the frequency, rate or extent of striated muscle development. GO:0016203 muscle attachment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016203 The developmental process in which a skeletal muscle attaches to its target (such as bone or body wall). GO:0016204 determination of muscle attachment site biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016204 The process that mediates the transfer of information from the cells of a muscle to those of its intended target, thereby identifying the target site. GO:0016205 selenocysteine methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016205 MetaCyc:RXN-11061|RHEA:26341|EC:2.1.1.280 Catalysis of the reaction: selenocysteine + S-adenosyl-L-methionine = Se-methylselenocysteine + S-adenosyl-homocysteine. GO:0090143 nucleoid organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090143 nucleoid organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleoid. The nucleoid is the region of a bacterial cell, virion, mitochondrion or chloroplast to which the DNA is confined. GO:0090144 mitochondrial nucleoid organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090144 mitochondrial nucleoid organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial nucleoid. The mitochondrial nucleoid is the region of a mitochondrion to which the DNA is confined. GO:0031840 type 2 neuromedin U receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031840 type 2 neuromedin U receptor ligand Interacting selectively and non-covalently with a type 2 neuromedin U receptor. GO:0016200 synaptic target attraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016200 The process in which a neuronal cell in a multicellular organism recognizes chemoattractant signals from, and grows towards, potential targets. GO:0090141 positive regulation of mitochondrial fission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090141 positive regulation of mitochondrial division Any process that increases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments. GO:0016201 synaptic target inhibition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0016201 The process in which a neuronal cell in a multicellular organism recognizes chemorepellent signals that inhibit its growth toward the source. GO:0090142 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090142 GO:0090147 regulation of establishment of mitochondrion localization involved in mitochondrial fission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090147 regulation of establishment of mitochondrion localisation involved in mitochondrial fission|regulation of mitochondrial localization involved in mitochondrial fission Any process that modulates the frequency, rate or extent of the directed movement of mitochondria to the correct region of the cell that contributes to the process of mitochondrial fission. GO:0090148 membrane fission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090148 membrane scission A process that is carried out at the cellular level which results in the separation of a single continuous membrane into two membranes. CHEBI:32480 D-gamma-glutamyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32480 GO:0090145 mitochondrial nucleoid organization involved in mitochondrial fission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090145 mitochondrial nucleoid organisation involved in mitochondrial fission A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial nucleoid that contributes to mitochondrial division. GO:0090146 establishment of mitochondrion localization involved in mitochondrial fission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090146 establishment of mitochondrion localisation involved in mitochondrial fission|mitochondrial localization involved in mitochondrial fission The directed movement of mitochondria to the correct region of the cell that contributes to the process of mitochondrial fission. CHEBI:32482 D-glutamo group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32482 GO:0031836 neuromedin K receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031836 neuromedin K receptor ligand|neurokinin-B receptor binding Interacting selectively and non-covalently with a neuromedin K receptor. GO:0031837 substance K receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031837 neurokinin-A receptor binding|substance K receptor ligand Interacting selectively and non-covalently with a substance K receptor. GO:0031834 neurokinin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031834 neurokinin receptor ligand Interacting selectively and non-covalently with a neurokinin receptor. GO:0031835 substance P receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031835 neurokinin-1 receptor binding|substance P receptor ligand Interacting selectively and non-covalently with a substance P receptor. GO:0090150 establishment of protein localization to membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090150 establishment of protein localisation in membrane|establishment of protein localization in membrane The directed movement of a protein to a specific location in a membrane. GO:0031832 type 6 serotonin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031832 5-hydroxytryptamine 6 receptor binding|type 6 serotonin receptor ligand Interacting selectively and non-covalently with a type 6 serotonin receptor. GO:0006898 receptor-mediated endocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006898 Wikipedia:Receptor-mediated_endocytosis receptor mediated endocytosis An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles. GO:0031833 type 7 serotonin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031833 5-hydroxytryptamine 7 receptor binding|type 7 serotonin receptor ligand Interacting selectively and non-covalently with a type 7 serotonin receptor. GO:0090151 establishment of protein localization to mitochondrial membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090151 establishment of protein localisation in mitochondrial membrane|establishment of protein localization in mitochondrial membrane The directed movement of a protein to a specific location in the mitochondrial membrane. GO:0006899 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006899 GO:0006896 Golgi to vacuole transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006896 Golgi to vacuole vesicle-mediated transport The directed movement of substances from the Golgi to the vacuole. GO:0031830 type 5A serotonin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031830 type 5A serotonin receptor ligand|5-hydroxytryptamine 5A receptor binding Interacting selectively and non-covalently with a type 5A serotonin receptor. GO:0006897 endocytosis biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0006897 Wikipedia:Endocytosis vesicle endocytosis|plasma membrane invagination|endocytic import into cell|nonselective vesicle endocytosis A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle. GO:0031831 type 5B serotonin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031831 type 5B serotonin receptor ligand|5-hydroxytryptamine 5B receptor binding Interacting selectively and non-covalently with a type 5B serotonin receptor. GO:0006894 obsolete Golgi to secretory vesicle transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006894 Golgi to secretory vesicle transport|Golgi to secretory vesicle transport, vesicle-mediated OBSOLETE. The directed movement of proteins from the Golgi to one of two types of secretory vesicle. Continuously secreted proteins are sorted into transport vesicles that fuse with the plasma membrane, releasing their contents by exocytosis. Specialized secretory cells have a second secretory pathway in which soluble proteins and other substances are initially stored in secretory vesicles for later release. GO:0006895 Golgi to endosome transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006895 TGN to endosome transport|Golgi to endosome vesicle-mediated transport|trans-Golgi to endosome transport The directed movement of substances from the Golgi to early sorting endosomes. Clathrin vesicles transport substances from the trans-Golgi to endosomes. GO:0006892 post-Golgi vesicle-mediated transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006892 post-Golgi transport The directed movement of substances from the Golgi to other parts of the cell, including organelles and the plasma membrane, mediated by small transport vesicles. GO:0006893 Golgi to plasma membrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006893 Golgi to plasma membrane vesicle-mediated transport The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis. GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006890 cis-Golgi to rough endoplasmic reticulum vesicle-mediated transport|retrograde vesicle-mediated transport, Golgi to ER|cis-Golgi to rough ER vesicle-mediated transport|cis-Golgi to rough ER transport|retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum|cis-Golgi to rough endoplasmic reticulum transport|retrograde transport, Golgi to ER|retrograde (Golgi to ER) transport|retrograde transport, Golgi to endoplasmic reticulum The directed movement of substances from the Golgi back to the endoplasmic reticulum, mediated by vesicles bearing specific protein coats such as COPI or COG. GO:0006891 intra-Golgi vesicle-mediated transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006891 intra-Golgi transport The directed movement of substances within the Golgi, mediated by small transport vesicles. These either fuse with the cis-Golgi or with each other to form the membrane stacks known as the cis-Golgi reticulum (network). GO:0031838 haptoglobin-hemoglobin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031838 A protein complex formed by the stable binding of a haptoglobin to hemoglobin. GO:0031839 type 1 neuromedin U receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031839 type 1 neuromedin U receptor ligand Interacting selectively and non-covalently with a type 1 neuromedin U receptor. GO:0016217 N-ethylammeline chlorohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016217 MetaCyc:R465-RXN Catalysis of the reaction: deethylsimazine + H2O = N-ethylammeline + chloride + H+. CHEBI:32494 D-phenylalaninate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32494 GO:0016218 obsolete polyketide synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016218 polyketide synthase activity OBSOLETE. (Was not defined before being made obsolete). CHEBI:32495 D-phenylalaninium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32495 GO:0016219 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016219 GO:0016213 linoleoyl-CoA desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016213 MetaCyc:1.14.19.3-RXN|Reactome:R-HSA-2046096|EC:1.14.19.3|Reactome:R-HSA-2046099|Reactome:R-HSA-2046097|Reactome:R-HSA-2046084|RHEA:22196 linoleic acid desaturase activity|delta6-acyl CoA desaturase activity|linoleoyl CoA desaturase activity|fatty acid delta6-desaturase activity|delta6-desaturase activity|delta(6)-fatty acyl-CoA desaturase activity|fatty acid 6-desaturase activity|long-chain fatty acid delta(6)-desaturase activity|delta6-fatty acyl-CoA desaturase activity|linoleate desaturase activity|linoleoyl-CoA,hydrogen-donor:oxygen oxidoreductase activity|long-chain fatty acid delta6-desaturase activity|linoleoyl-coenzyme A desaturase activity|fatty acid delta(6)-desaturase activity|linoleic desaturase activity|delta(6)-desaturase activity|delta(6)-acyl CoA desaturase activity Catalysis of the reaction: linoleoyl-CoA + reduced acceptor + O2 = gamma-linolenoyl-CoA + acceptor + 2 H2O. GO:0016214 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0016214 GO:0016215 acyl-CoA desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016215 EC:1.14.19.- CoA desaturase activity Catalysis of the reaction: acyl-CoA + reduced acceptor + O2 = desaturated-acyl-CoA + acceptor + 2 H2O. GO:0016216 isopenicillin-N synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016216 EC:1.21.3.1|RHEA:22428|MetaCyc:1.21.3.1-RXN|KEGG_REACTION:R04872 isopenicillin N synthase activity|N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine:oxygen oxidoreductase (cyclizing)|isopenicillin-N synthetase activity Catalysis of the reaction: N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + O(2) = 2 H(2)O + isopenicillin N. GO:0090154 positive regulation of sphingolipid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090154 Any process that increases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). GO:0016210 naringenin-chalcone synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016210 MetaCyc:NARINGENIN-CHALCONE-SYNTHASE-RXN|RHEA:11128|EC:2.3.1.74 malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)|DOCS Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2. GO:0090155 negative regulation of sphingolipid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090155 negative regulation of sphingolipid biosynthesis involved in cellular sphingolipid homeostasis Any process that decreases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). GO:0090152 establishment of protein localization to mitochondrial membrane involved in mitochondrial fission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090152 establishment of protein localisation in mitochondrial membrane involved in mitochondrial fission|establishment of protein localization in mitochondrial membrane involved in mitochondrial fission The directed movement of a protein to a specific location in the mitochondrial membrane that contributes to mitochondrial fission. GO:0016211 ammonia ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016211 EC:6.3.1.- Catalysis of the ligation of ammonia (NH3) to another substance via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate. GO:0016212 kynurenine-oxoglutarate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0016212 Reactome:R-HSA-901097|Reactome:R-HSA-893596|Reactome:R-HSA-893583|RHEA:20964|MetaCyc:2.6.1.7-RXN|EC:2.6.1.7 L-kynurenine aminotransferase activity|kynurenine transaminase (cyclizing)|kynurenine aminotransferase activity|L-kynurenine:2-oxoglutarate aminotransferase activity|kynurenine--oxoglutarate aminotransferase activity|kynurenine 2-oxoglutarate transaminase activity|kynurenine-oxoglutarate aminotransferase activity Catalysis of the reaction: L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate. GO:0090153 regulation of sphingolipid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090153 Any process that modulates the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). GO:0090158 endoplasmic reticulum membrane organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090158 endoplasmic reticulum membrane organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an endoplasmic reticulum membrane. GO:0090159 sphingolipid biosynthesis involved in endoplasmic reticulum membrane organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090159 sphingolipid biosynthesis involved in endoplasmic reticulum membrane organisation The chemical reactions and pathways resulting in the formation of sphingolipids that contributes to endoplasmic reticulum membrane organization. GO:0090156 cellular sphingolipid homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090156 Any biological process involved in the maintenance of an internal steady state of sphingolipids at the level of the cell. GO:0090157 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090157 GO:0006869 lipid transport biolink:BiologicalProcess go-plus goslim_pir|goslim_drosophila|goslim_yeast http://purl.obolibrary.org/obo/GO_0006869 The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. GO:0031825 type 1F serotonin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031825 type 1F serotonin receptor ligand|5-hydroxytryptamine 1F receptor binding Interacting selectively and non-covalently with a type 1F serotonin receptor. GO:0031826 type 2A serotonin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031826 type 2A serotonin receptor ligand|5-hydroxytryptamine 2A receptor binding Interacting selectively and non-covalently with a type 2A serotonin receptor. GO:0031823 type 1D serotonin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031823 5-hydroxytryptamine 1D receptor binding|type 1D serotonin receptor ligand Interacting selectively and non-covalently with a type 1D serotonin receptor. GO:0006867 asparagine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006867 L-asparagine transport The directed movement of asparagine, alpha-aminosuccinamic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0031824 type 1E serotonin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031824 5-hydroxytryptamine 1E receptor binding|type 1E serotonin receptor ligand Interacting selectively and non-covalently with a type 1E serotonin receptor. GO:0006868 glutamine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006868 L-glutamine transport The directed movement of glutamine, 2-amino-4-carbamoylbutanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0006865 amino acid transport biolink:BiologicalProcess go-plus goslim_pir|goslim_yeast http://purl.obolibrary.org/obo/GO_0006865 The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0031821 G protein-coupled serotonin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031821 metabotropic serotonin receptor ligand|metabotropic 5-hydroxytryptamine receptor binding|metabotropic serotonin receptor binding|G-protein coupled serotonin receptor binding Interacting selectively and non-covalently with a metabotropic serotonin receptor. GO:0006866 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006866 GO:0031822 type 1B serotonin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031822 5-hydroxytryptamine 1B receptor binding|type 1B serotonin receptor ligand Interacting selectively and non-covalently with a type 1B serotonin receptor. GO:0006863 purine nucleobase transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006863 purine base transport|purine base transmembrane transport|purine transport|purine transmembrane transport The directed movement of purine bases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0031820 P2Y11 nucleotide receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031820 P2Y11 nucleotide receptor ligand Interacting selectively and non-covalently with a P2Y11 nucleotide receptor. GO:0006864 pyrimidine nucleotide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006864 The directed movement of a pyrimidine nucleotide, any compound consisting of a pyrimidine nucleoside esterified with (ortho)phosphate, into, out of or within a cell. GO:0006861 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006861 GO:0006862 nucleotide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006862 The directed movement of a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate, into, out of or within a cell. GO:0006860 extracellular amino acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006860 The directed extracellular movement of amino acids. GO:0031829 type 4 serotonin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031829 type 4 serotonin receptor ligand|5-hydroxytryptamine 4 receptor binding Interacting selectively and non-covalently with a type 4 serotonin receptor. GO:0031827 type 2B serotonin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031827 type 2B serotonin receptor ligand|5-hydroxytryptamine 2B receptor binding Interacting selectively and non-covalently with a type 2B serotonin receptor. GO:0031828 type 2C serotonin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031828 type 2C serotonin receptor ligand|5-hydroxytryptamine 2C receptor binding Interacting selectively and non-covalently with a type 2C serotonin receptor. CHEBI:32461 cysteinate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32461 CHEBI:32462 L-alpha-aspartyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32462 CHEBI:32466 D-alpha-aspartyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32466 CHEBI:32460 cysteine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32460 GO:0031814 P2Y4 nucleotide receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031814 P2Y4 nucleotide receptor ligand Interacting selectively and non-covalently with a P2Y4 nucleotide receptor. GO:0031815 P2Y5 nucleotide receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031815 P2Y5 nucleotide receptor ligand Interacting selectively and non-covalently with a P2Y5 nucleotide receptor. GO:0031812 P2Y1 nucleotide receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031812 P2Y1 nucleotide receptor ligand Interacting selectively and non-covalently with a P2Y1 nucleotide receptor. GO:0006878 cellular copper ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006878 copper homeostasis Any process involved in the maintenance of an internal steady state of copper ions at the level of a cell. GO:0031813 P2Y2 nucleotide receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031813 P2Y2 nucleotide receptor ligand Interacting selectively and non-covalently with a P2Y2 nucleotide receptor. GO:0006879 cellular iron ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006879 iron homeostasis Any process involved in the maintenance of an internal steady state of iron ions at the level of a cell. GO:0006876 cellular cadmium ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006876 cadmium homeostasis Any process involved in the maintenance of an internal steady state of cadmium ions at the level of a cell. GO:0031810 H4 histamine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031810 H4 histamine receptor ligand Interacting selectively and non-covalently with a H4 histamine receptor. GO:0031811 G protein-coupled nucleotide receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031811 metabotropic nucleotide receptor ligand|G-protein coupled nucleotide receptor binding|metabotropic nucleotide receptor binding|P2Y receptor binding Interacting selectively and non-covalently with a G protein-coupled (metabotropic) nucleotide receptor. GO:0006877 cellular cobalt ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006877 cobalt homeostasis Any process involved in the maintenance of an internal steady state of cobalt ions at the level of a cell. GO:0006874 cellular calcium ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006874 regulation of calcium ion concentration Any process involved in the maintenance of an internal steady state of calcium ions at the level of a cell. GO:0006875 cellular metal ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006875 cellular heavy metal ion homeostasis Any process involved in the maintenance of an internal steady state of metal ions at the level of a cell. GO:0006872 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006872 UBERON:0007838 spinal cord white commissure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007838 white commissure of spinal cord GO:0006873 cellular ion homeostasis biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0006873 Any process involved in the maintenance of an internal steady state of ions at the level of a cell. GO:0006870 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006870 GO:0006871 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006871 GO:0031818 P2Y9 nucleotide receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031818 P2Y9 nucleotide receptor ligand Interacting selectively and non-covalently with a P2Y9 nucleotide receptor. GO:0031819 P2Y10 nucleotide receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031819 P2Y10 nucleotide receptor ligand Interacting selectively and non-covalently with a P2Y10 nucleotide receptor. GO:0031816 P2Y6 nucleotide receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031816 P2Y6 nucleotide receptor ligand Interacting selectively and non-covalently with a P2Y6 nucleotide receptor. GO:0031817 P2Y8 nucleotide receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031817 P2Y8 nucleotide receptor ligand Interacting selectively and non-covalently with a P2Y8 nucleotide receptor. UBERON:0007842 membrane bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007842 membrane bones Bone element that arises as a result of intramembranous ossification. CHEBI:32474 L-gamma-glutamyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32474 UBERON:0007844 cartilage element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007844 chondrogenic element|cartilaginous element|cartilage|cartilage organ Skeletal element that is composed of cartilage tissue and may be permanent or transient. CHEBI:4208 D-mannopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_4208 UBERON:0007845 regular connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007845 Connective tissue, which consists of fibroblasts, the intercellular matrix of which contains a regular network of collagen and elastic fiber bundles. Examples: bone (tissue), cartilage (tissue), dense regular connective tissue. UBERON:0007846 dense regular connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007846 dense regular collagenous connective tissue|typus regularis (textus connectivus collagenosus compactus)|dense regular collagenous tissue|regular dense connective tissue|dense fibrous connective tissue Connective tissue that is dominated by collagen fibres organized into a definitive pattern (e.g., parallel to one another), with comparatively fewer cells (mostly fibroblasts). CHEBI:32479 D-alpha-glutamyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32479 CHEBI:32470 aspartic acid residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32470 CHEBI:32471 aspartate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32471 GO:0031803 type 6 metabotropic glutamate receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031803 type 6 metabotropic glutamate receptor ligand Interacting selectively and non-covalently with a type 6 metabotropic glutamate receptor. GO:0006847 plasma membrane acetate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006847 The directed movement of acetate across a plasma membrane. GO:0006848 pyruvate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006848 The directed movement of pyruvate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0090180 positive regulation of thiamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090180 positive regulation of thiamin biosynthetic process Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine. GO:0031804 type 7 metabotropic glutamate receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031804 type 7 metabotropic glutamate receptor ligand Interacting selectively and non-covalently with a type 7 metabotropic glutamate receptor. GO:0031801 type 4 metabotropic glutamate receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031801 type 4 metabotropic glutamate receptor ligand Interacting selectively and non-covalently with a type 4 metabotropic glutamate receptor. GO:0006845 obsolete mitochondrial aspartate/glutamate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006845 mitochondrial aspartate/glutamate transport OBSOLETE. The directed movement of aspartate and glutamate into, out of or within a mitochondrion. GO:0031802 type 5 metabotropic glutamate receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031802 type 5 metabotropic glutamate receptor ligand Interacting selectively and non-covalently with a type 5 metabotropic glutamate receptor. GO:0006846 acetate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006846 The directed movement of acetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0090183 regulation of kidney development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090183 regulation of nephrogenesis Any process that modulates the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. GO:0006843 mitochondrial citrate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006843 mitochondrial citrate transport The directed movement of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, into or out of a mitochondrial matrix. GO:0031800 type 3 metabotropic glutamate receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031800 type 3 metabotropic glutamate receptor ligand Interacting selectively and non-covalently with a type 3 metabotropic glutamate receptor. GO:0006844 acyl carnitine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006844 The directed movement of acyl carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acyl carnitine is the condensation product of a carboxylic acid and carnitine and is the transport form for a fatty acid crossing the mitochondrial membrane. GO:0090184 positive regulation of kidney development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090184 positive regulation of nephrogenesis Any process that increases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. GO:0006841 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006841 GO:0090181 regulation of cholesterol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090181 Any process that modulates the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. GO:0090182 regulation of secretion of lysosomal enzymes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090182 Any process that modulates the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell. GO:0006842 tricarboxylic acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006842 The directed movement of tricarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UBERON:0007827 external nose biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007827 nose External part of the nose containing the external nares. CHEBI:32447 L-cysteinyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32447 GO:0006840 obsolete mitochondrial alpha-ketoglutarate/malate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006840 mitochondrial oxoglutarate/malate transport|mitochondrial alpha-ketoglutarate/malate transport OBSOLETE. The directed movement of alpha-ketoglutarate and malate into, out of or within a mitochondrion. UBERON:0007828 girdle bone/zone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007828 girdle bone A bone that is part of a appendage girdle region. CHEBI:32448 L-cysteino group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32448 UBERON:0007829 pectoral girdle bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007829 bone of pectoral girdle A bone that is part of a pectoral girdle region. GO:0031809 H3 histamine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031809 H3 histamine receptor ligand Interacting selectively and non-covalently with a H3 histamine receptor. CHEBI:32449 D-cysteinate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32449 GO:0031807 H1 histamine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031807 H1 histamine receptor ligand Interacting selectively and non-covalently with a H1 histamine receptor. GO:0031808 H2 histamine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031808 H2 histamine receptor ligand Interacting selectively and non-covalently with a H2 histamine receptor. GO:0031805 type 8 metabotropic glutamate receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031805 type 8 metabotropic glutamate receptor ligand Interacting selectively and non-covalently with a type 8 metabotropic glutamate receptor. GO:0031806 G protein-coupled histamine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031806 metabotropic histamine receptor binding|metabotropic histamine receptor ligand|G-protein coupled histamine receptor binding Interacting selectively and non-covalently with a G protein-coupled (metabotropic) histamine receptor. UBERON:0007830 pelvic girdle bone/zone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007830 pelvic girdle bone|bone of pelvic girdle A bone element or fused bone that is part of pelvic girdle. UBERON:0007831 pectoral girdle skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007831 skeletal parts of pectoral girdle|pectoral girdle|skeleton of pectoral girdle|scapular girdle|cingulum pectorale A subdivision of a limb or fin skeleton consisting of bones which connects the upper limb or fin to the axial skeleton on each side. It consists of the clavicle and scapula in humans and, in those species with three bones in the pectoral girdle, the coracoid. Some mammalian species (e.g. the dog and the horse) have only the scapula. In humans, the only joints between the shoulder girdle and axial skeleton are the sternoclavicular joints on each side. No joint exists between each scapula and the rib cage; instead the muscular connection between the two permits relatively great mobility of the shoulder girdle in relation to the pelvic girdle. In those species having only the scapula, no joint exists between the forelimb and the thorax, the only attachment being muscular[WP]. Examples: There are only two instances, right and left pectoral girdle skeletons. CHEBI:32440 alaninium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32440 UBERON:0007832 pelvic girdle skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007832 pelvic girdle skeleton|skeletal parts of pelvic girdle|pelvic girdle|skeleton of pelvic girdle Skeletal subdivision consisting of a set of bones linking the axial series to the hindlimb zeugopodium and offering anchoring areas for hindlimb and caudal musculature. CHEBI:32442 L-cysteinate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32442 CHEBI:32443 L-cysteinate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32443 UBERON:0007836 cervical spinal cord ventral commissure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007836 cervical spinal cord anterior commissure A spinal cord ventral commissure that is part of a cervical spinal cord. CHEBI:32445 L-cysteinium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32445 PATO:0001396 cellular quality biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PATO_0001396 A monadic quality of continuant that exists at the cellular level of organisation. UBERON:0007837 thoracic spinal cord ventral commissure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007837 thoracic spinal cord anterior commissure A spinal cord ventral commissure that is part of a thoracic spinal cord. CHEBI:32446 all-trans-neoxanthin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32446 GO:0090187 positive regulation of pancreatic juice secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090187 Any process that increases the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine. GO:0090188 negative regulation of pancreatic juice secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090188 Any process that decreases the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine. GO:0090185 negative regulation of kidney development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090185 negative regulation of nephrogenesis Any process that decreases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. GO:0090186 regulation of pancreatic juice secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090186 Any process that modulates the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine. GO:0090189 regulation of branching involved in ureteric bud morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090189 Any process that modulates the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules. GO:0006849 plasma membrane pyruvate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006849 The directed movement of pyruvate, 2-oxopropanoate, across a plasma membrane. GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090190 Any process that increases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules. GO:0006858 extracellular transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006858 The transport of substances that occurs outside cells. GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090191 Any process that decreases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules. GO:0006859 extracellular carbohydrate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006859 The directed extracellular movement of carbohydrates. GO:0006856 eye pigment precursor transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006856 The directed movement of eye pigment precursors, the inactive forms of visual pigments, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0006857 oligopeptide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006857 The directed movement of oligopeptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages. GO:0006854 obsolete ATP/ADP exchange biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006854 ATP/ADP exchange OBSOLETE. (Was not defined before being made obsolete). GO:0090194 negative regulation of glomerulus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090194 Any process that decreases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney. GO:0090195 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090195 GO:0006855 drug transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006855 multidrug transport|drug membrane transport The process in which a drug is transported across a membrane. GO:0006852 obsolete mitochondrial sodium/calcium ion exchange biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006852 mitochondrial sodium/calcium exchange|mitochondrial sodium/calcium ion exchange OBSOLETE. (Was not defined before being made obsolete). GO:0090192 regulation of glomerulus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090192 Any process that modulates the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney. GO:0090193 positive regulation of glomerulus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090193 Any process that increases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney. GO:0006853 carnitine shuttle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006853 Wikipedia:Carnitine#Role_in_fatty_acid_metabolism The transfer of acyl groups to and from acyl-CoA molecules to form O-acylcarnitine, which can exchange across the mitochondrial inner membrane with unacylated carnitine. GO:0006850 mitochondrial pyruvate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006850 pyruvate transmembrane transport in mitochondrion|pyruvate membrane transport in mitochondria|pyruvate membrane transport in mitochondrion|pyruvate transmembrane transport in mitochondria|mitochondrial pyruvate transport The process in which pyruvate is transported across a mitochondrial membrane, into or out of the mitochondrion. CHEBI:32458 cysteinium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32458 GO:0006851 mitochondrial calcium ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006851 mitochondrial calcium transport The process in which a calcium ion (Ca2+) is transported across a mitochondrial membrane, into or out of the mitochondrion. CHEBI:32459 cysteino group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32459 CHEBI:32450 D-cysteinate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32450 CHEBI:32451 D-cysteinium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32451 CHEBI:32452 D-cysteinyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32452 CHEBI:32453 D-cysteino group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32453 UBERON:0007823 appendage girdle region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007823 girdle|fin girdle|girdle region|limb girdle|limb girdle region|fin girdle region An organism subdivision that encompasses the region containing the pectoral or pelvic girdle. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc). CHEBI:32456 cysteinate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32456 CHEBI:32457 cysteinate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32457 UBERON:0007826 peritoneal mesentery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007826 Mesentery that is located in the peritoneum. GO:0090198 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090198 GO:0090199 regulation of release of cytochrome c from mitochondria biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0090199 Any process that modulates the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation. GO:0090196 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090196 GO:0090197 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0090197 CHEBI:22187 acetophenones biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22187 UBERON:0003968 peripheral lymph node biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003968 The lymph nodes located outside the thoracic and abdominal cavities, such as the submandibular, prescapular, axillary, inguinal and popliteal lymph nodes UBERON:0003967 cutaneous elastic tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003967 cutaneous elastic fiber|dermal elastic fiber The slender connective tissue fiber in the extracellular matrix of skin tissue that is composed of microfibrils and amorphous elastin and is characterized by great elasticity NCBITaxon:33090 Viridiplantae organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_33090 Chlorophyta/Embryophyta group|Chlorobionta|green plants|chlorophyte/embryophyte group|Chloroplastida|green plants CHEBI:22180 EC 2.2.1.6 (acetolactate synthase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22180 CHEBI:61796 dinoflagellate luciferin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61796 CHEBI:61799 beta-D-galactopyranosyl diglyceride biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61799 UBERON:0003975 internal female genitalia biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003975 female internal genitalia|internal female genital organ|organa genitalia feminina interna|internal genitalia of female reproductive system The internal feminine genital organs, including the ovaries, uterine tubes, uterus, uterine cervix, and vagina. UBERON:0003970 placental labyrinth vasculature biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003970 vasculature of placenta labyrinth|placental labyrinth vascular network|placental vasculature blood vessels of the layer of the placenta where embryonic and maternal blood vessels interdigitate UBERON:0003959 rete testis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003959 Haller's rete An anastomosing network of delicate tubules located in the hilum of the testicle (mediastinum testis) that carries sperm from the seminiferous tubules to the vasa efferentia[WP]. CHEBI:22198 acetylcysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22198 NCBITaxon:33083 Dictyostelia organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_33083 Dictyostelida|Dictyosteliida|cellular slime molds|Dictyostelids|dictyostelid cellular slime molds UBERON:0003956 aqueous drainage system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003956 The structures associated with drainage of the aqueous humor from the eye, that include the trabecular meshwork, Schlemm's canal, the uveoscleral network, and the aqueous veins CHEBI:22193 acetyl-L-lysine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22193 CHEBI:131845 2-methylpropane-1,2-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131845 CHEBI:22191 acetyl phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_22191 CHEBI:131846 2-hydroxy-2-methylpropanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131846 CHEBI:131847 2,4-didehydro-3-deoxy-L-rhamnonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131847 CHEBI:131849 D-erythritol 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131849 CHEBI:22194 acetyl-L-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22194 CHEBI:46143 UDP-N-acetyl-alpha-muramoyl-L-alanyl-D-glutamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46143 CHEBI:22195 acetyl-amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22195 UBERON:0003946 placenta labyrinth biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003946 placental labyrinth|labyrinthine layer|labyrinthine layer of placenta The placental layers where embryonic blood vessels are surrounded by trophoblast cells and maternal blood UBERON:0003947 brain ventricle/choroid plexus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003947 The brain ventricles or their associated choroid plexuses CHEBI:22160 acetamides biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22160 CHEBI:85780 N-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85780 CHEBI:85783 1,2-dihexadecanoyl-sn-glycero-3-phosphoglycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85783 CHEBI:85784 N-arachidonoyl-1,2-dioleoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85784 PR:000012826 urokinase-type plasminogen activator biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000012826 PLAU|uPA|U-plasminogen activator A protein that is a translation product of the human PLAU gene or a 1:1 ortholog thereof. CHEBI:85785 monodechloroaminopyrrolnitrin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85785 CHEBI:85786 aminopyrrolnitrin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85786 CHEBI:85787 1-decanoyl-2-oleoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85787 UBERON:0003953 posterior stroma of cornea biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003953 cornea posterior stroma|posterior stroma The posterior segment of the lamellated connective tissue layer of the cornea UBERON:0003952 anterior stroma of cornea biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003952 anterior stroma|cornea anterior stroma The anterior segment of the lamellated connective tissue layer of the cornea CHEBI:22179 acetohydroximates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22179 UBERON:0003937 reproductive gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003937 sex gland|gland of reproductive system|genitalia gland|reproductive gland|reproductive system gland|gland of genitalia Any of the organized aggregations of cells that function as secretory or excretory organs and are associated with reproduction. CHEBI:22177 acetohydroxamic acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22177 UBERON:0003935 mesenchyme pelvic fin biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003935 mesenchyme of pelvic fin|mesenchyme pelvic fins|pelvic fin mesenchyme Mesenchyme that is part of a developing pelvic fin [Automatically generated definition]. UBERON:0003933 cranial cartilage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003933 cranium cartilage|cartilage of cranium|cranial cartilages A cartilage element that is part of the cranial skeleton. UBERON:0003934 mesenchyme pectoral fin biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003934 mesenchyme pectoral fins|mesenchyme of pectoral fin|pectoral fin mesenchyme Mesenchyme that is part of a developing pectoral fin [Automatically generated definition]. CHEBI:131822 sulfamate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131822 CHEBI:131823 methylated primary amine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131823 CHEBI:85777 Cer(d42:1) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85777 CHEBI:85778 4beta-hydroxycholesterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85778 CHEBI:85779 4beta,7alpha-dihydroxycholesterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85779 UBERON:0003942 somatic sensory system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003942 somatosensory system|somatic sensory system|system for detection of somatic senses The sensory system for the sense of touch and pain. CHEBI:71156 N-acyl-15-methylhexadecasphing-4-enine-1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71156 CHEBI:22144 abscisic aldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_22144 CHEBI:36786 tetralins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36786 CHEBI:36785 carbobicyclic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36785 CHEBI:36782 tetraterpenyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36782 CHEBI:36783 apo carotenoid triterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36783 CHEBI:36780 triterpenyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36780 CHEBI:36781 1-pyrrolinium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36781 CHEBI:22156 acenaphthenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22156 CHEBI:22154 acenaphthene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_22154 CHEBI:85790 N,1,2-trioleoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85790 CHEBI:85791 N-stearoyl-1,2-dioleoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85791 CHEBI:131803 L-allysine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131803 CHEBI:85793 N-myristoyl-1,2-dioleoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85793 CHEBI:22152 2-cis-abscisic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22152 CHEBI:22153 acaricide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22153 CHEBI:85794 N-lauroyl-1,2-dioleoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85794 CHEBI:22151 (+)-abscisic acid beta-D-glucopyranosyl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_22151 CHEBI:85796 N-capryl-1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85796 CHEBI:85797 N-capryloyl-1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85797 CHEBI:85798 N-caproyl-1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85798 CHEBI:85799 N-butyryl-1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85799 CHEBI:71163 2,3-didehydroadipoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71163 CHEBI:71164 (R)-lactoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71164 CHEBI:71165 N-acyl-15-methylhexadecasphing-4-enine-1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71165 UBERON:0003988 thymus corticomedullary boundary biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003988 thymic corticomedullary junction|thymus corticomedullary zone|thymus CMZ|thymic corticomedullary zone|thymic corticomedullary boundary|thymic cortico-medullary boundary|thymus cortico-medullary boundary|thymus corticomedullary junction The dense region demarcating the thymus medulla from the surrounding cortex that is characterized by numerous blood vessels (predominantly arterioles) with some perivascular connective tissue, mature and immature T lymphocytes, dendritic cells, variable numbers of perivascular B-lymphocytes and plasma cells; site of entry of bone marrow stem cells and exit of mature, functional T cells CHEBI:36765 gibberellane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36765 CHEBI:36762 abietane diterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36762 CHEBI:36768 casbane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36768 CHEBI:36766 ent-gibberellane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36766 CHEBI:36760 ent-kaurane diterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36760 CHEBI:71175 7,8-dihydromonapterin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71175 CHEBI:36761 1-pyrroline-2-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36761 CHEBI:71177 tetrahydromonapterin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71177 CHEBI:71189 iminodiacetonitrile biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71189 UBERON:0003978 valve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003978 anatomical valve CHEBI:36775 bornane-2,5-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36775 CHEBI:36776 (1S)-bornane-2,5-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36776 CHEBI:36773 camphor biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36773 CHEBI:71181 Sir2 inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71181 UBERON:0003984 uterine tube infundibulum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003984 infundibulum tubae uterinae|infundibulum of uterine tube|infundibulum of fallopian tube|infundibulum of oviduct|infundibulum The funnel-like expansion of the abdominal extremity of the uterine tube[MP] CHEBI:71185 methyl 3-cyano-2-phenylpropanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71185 UBERON:0003983 conus arteriosus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003983 A conical pouch formed from the upper and left angle of the right ventricle in the chordate heart, from which the pulmonary artery arises[WP]. the anteriosuperior, smooth-walled portion of the cavity of the right ventricle, beginning at the supraventricular crest and terminates in the pulmonary trunk[MP]. CHEBI:36772 diterpenyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36772 UBERON:0003980 cerebellum fissure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003980 fissurae cerebelli|set of cerebellar fissures|cerebellar sulci|cerebellar fissure|sulcus of cerebellum|cerebellar sulcus|cerebellar fissures set|cerebellar fissures One of a set of deep furrows which divide the lobules of the cerebellum. Examples: postcentral, primary and secondary furrows CHEBI:71187 3beta-hydroxy-4alpha-carboxysteroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71187 UBERON:0003981 primordial ovarian follicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003981 ovary primordial follicle|primordial follicle primordial follicles are indiscernible to the naked eye and develop to primary, secondary, and finally mature vesicular follicles CHEBI:36770 labdane diterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36770 CHEBI:71188 3-oxocyclopentanecarbonitrile biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71188 GO:0035548 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035548 GO:0035549 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035549 GO:0035540 positive regulation of SNARE complex disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035540 Any process that increases the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. GO:0035541 negative regulation of SNARE complex disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035541 Any process that decreases the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. GO:0035542 regulation of SNARE complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035542 Any process that modulates the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. GO:0035543 positive regulation of SNARE complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035543 Any process that increases the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. GO:0035544 negative regulation of SNARE complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035544 Any process that decreases the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. GO:0035545 determination of left/right asymmetry in nervous system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035545 The establishment of the nervous system with respect to the left and right halves. GO:0035546 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035546 CHEBI:141249 N-carbamoyl-D-phenylglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_141249 GO:0035547 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035547 CHEBI:61717 ferroheme c(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61717 GO:0035537 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035537 GO:0035538 carbohydrate response element binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035538 ChoRE binding Interacting selectively and non-covalently with the carbohydrate response element (ChoRE) found in the promoters of genes whose expression is regulated in response to carbohydrates, such as the triglyceride synthesis genes. GO:0035539 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035539 Reactome:R-HSA-2395849|Reactome:R-HSA-2395869|RHEA:31575|EC:3.6.1.55 8-oxo-7,8-dihydrodeoxyguanosine triphosphatase activity|8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate pyrophosphohydrolase activity|8-oxo-dGTPase activity|8-oxo-7,8-dihydro-deoxyguanosine triphosphate pyrophosphatase activity|8-oxo-dGTP pyrophosphohydrolase activity Catalysis of the reaction: 8-oxo-7,8-dihydrodeoxyguanosine-triphosphate (8-oxo-dGTP) + H2O = 8-oxo-7,8-dihydrodeoxyguanosine phosphate (8-oxo-dGMP) + diphosphate. 8-oxo-dGTP is the oxidised form of the free guanine nucleotide and can act as a potent mutagenic substrate for DNA synthesis causing transversion mutations. 8-oxo-dGTPase hydrolyses 8-oxo-dGTP to its monophosphate form to prevent the misincorporation of 8-oxo-dGTP into cellular DNA. CHEBI:61720 bacteriochlorophyll a(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61720 GO:0035530 chemokine (C-C motif) ligand 6 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0035530 CCL6 production The appearance of chemokine (C-C motif) ligand 6 (CCL6) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. CHEBI:61721 chlorophyll b(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61721 GO:0035531 regulation of chemokine (C-C motif) ligand 6 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035531 regulation of chemokine (C-C motif) ligand 6 secretion|chemokine (C-C motif) ligand 6 secretion|regulation of CCL6 production Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6). GO:0035532 negative regulation of chemokine (C-C motif) ligand 6 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035532 negative regulation of CCL6 production|negative regulation of chemokine (C-C motif) ligand 6 secretion Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6). GO:0035533 positive regulation of chemokine (C-C motif) ligand 6 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035533 positive regulation of chemokine (C-C motif) ligand 6 secretion|positive regulation of CCL6 production Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6). GO:0035534 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035534 CHEBI:61725 oct-2-enal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61725 GO:0035535 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035535 CHEBI:61723 D-pantetheine 4'-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61723 GO:0035536 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035536 CHEBI:61727 dec-2-enal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61727 GO:0035526 retrograde transport, plasma membrane to Golgi biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035526 The directed movement of substances from the plasma membrane back to the trans-Golgi network, mediated by vesicles. GO:0035527 3-hydroxypropionate dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035527 RHEA:26438|KEGG_REACTION:R09289|EC:1.1.1.298|MetaCyc:RXN-8974 3-hydroxypropanoate dehydrogenase (NADP+) activity|3-hydroxypropionate:NADP+ oxidoreductase|3-hydroxypropanoate:NADP+ oxidoreductase Catalysis of the reaction: 3-hydroxypropanoate + NADP+ = 3-oxopropanoate + H+ + NADPH. GO:0035528 obsolete UDP-N-acetylglucosamine biosynthesis involved in chitin biosynthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035528 UDP-GlcNAc biosynthetic process involved in chitin biosynthetic process|UDP-GlcNAc biosynthesis involved in chitin biosynthesis|UDP-GlcNAc biosynthetic process involved in chitin biosynthesis|UDP-N-acetylglucosamine anabolism involved in chitin biosynthesis|UDP-N-acetylglucosamine synthesis involved in chitin biosynthesis|UDP-N-acetylglucosamine formation involved in chitin biosynthesis|UDP-N-acetylglucosamine biosynthetic process involved in chitin biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine in glycosidic linkage with uridine diphosphate, that contribute to the biosynthesis of chitin. GO:0035529 NADH pyrophosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035529 KEGG_REACTION:R00103|EC:3.6.1.9|Reactome:R-HSA-6809287|MetaCyc:RXN0-4401 NADH diphosphatase activity|NADH pyrophosphohydrolase activity Catalysis of the reaction: NADH + H2O = AMP + NMNH + 2 H+. CHEBI:61732 beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1->1')-Cer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61732 GO:0035520 monoubiquitinated protein deubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035520 monoubiquitinated protein deubiquitylation|monoubiquitinated protein deubiquitinylation The removal of the ubiquitin group from a monoubiquitinated protein. GO:0035521 monoubiquitinated histone deubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035521 monoubiquitinated histone deubiquitylation|monoubiquitinated histone deubiquitinylation The removal of the ubiquitin group from a monoubiquitinated histone protein. CHEBI:85701 diacylglycerol 36:2 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85701 GO:0035522 monoubiquitinated histone H2A deubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035522 monoubiquitinated histone H2A deubiquitylation|monoubiquitinated histone H2A deubiquitinylation The removal of the ubiquitin group from a monoubiquitinated histone H2A protein. CHEBI:131894 N-arachidonoylethanolamine phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131894 CHEBI:61735 lipid IIA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61735 GO:0035523 protein K29-linked deubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035523 protein K29-linked deubiquitylation|protein K29-linked deubiquitinylation A protein deubiquitination process in which a K29-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 29 of the ubiquitin monomers, is removed from a protein. CHEBI:61736 thujopsene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61736 GO:0035524 proline transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035524 proline membrane transport The directed movement of proline, pyrrolidine-2-carboxylic acid, across a membrane by means of some agent such as a transporter or pore. GO:0035525 NF-kappaB p50/p65 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035525 NF-kappa p105/RelA complex|NF-kappa B1/RelA complex|NF-kappa B1/p65 complex|NF-kappa p50/RelA complex|NF-kappa p105/p65 complex A heterodimer of NF-kappa B p50 and p65 subunits. CHEBI:61734 lipid IIA(3-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61734 CHEBI:61737 (+)-thujopsene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61737 GO:0035515 oxidative RNA demethylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035515 Reactome:R-HSA-8857692 2-oxoglutarate-dependent RNA demethylase Catalysis of the removal of a methyl group from one or more nucleosides within a RNA molecule involving the oxidation (i.e. electron loss) of one or more atoms. GO:0035516 oxidative DNA demethylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035516 2-oxoglutarate-dependent DNA demethylase Catalysis of the removal of the methyl group from one or more nucleotides within a DNA molecule involving the oxidation (i.e. electron loss) of one or more atoms. CHEBI:141211 (R)-3-hydroxyisobutyrate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_141211 GO:0035517 PR-DUB complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035517 Polycomb repressive deubiquitinase complex A multimeric protein complex that removes monoubiquitin from histone H2A. In Drosophila and mammals, the core of the complex is composed of Calypso/BAP1 and Asx/ASXL1, respectively. CHEBI:141212 (R)-methylmalonate semialdehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_141212 GO:0035518 histone H2A monoubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035518 The modification of histone H2A by addition of a single ubiquitin group. GO:0035519 protein K29-linked ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035519 protein K29-linked polyubiquitination A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 29 of the ubiquitin monomers, is added to a protein. K29-linked ubiquitination targets the substrate protein for degradation. CHEBI:141219 sulfoquinovosyldiacylglycerol 32:0 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_141219 GO:0035510 DNA dealkylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035510 The removal of an alkyl group from one or more nucleotides within an DNA molecule. GO:0035511 oxidative DNA demethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035511 Removal of the methyl group from one or more nucleotides within a DNA molecule involving the oxidation (i.e. electron loss) of one or more atoms. CHEBI:61746 (+)-beta-chamigrene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61746 GO:0035512 hydrolytic DNA demethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035512 The hydrolytic removal of the methyl group from one or more nucleotides within a DNA molecule. GO:0035513 oxidative RNA demethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035513 The removal of the methyl group from one or more nucleotides within an RNA molecule involving oxidation (i.e. electron loss) of one or more atoms. CHEBI:61744 beta-chamigrene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61744 GO:0035514 DNA demethylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035514 Catalysis of the removal of a methyl group from one or more nucleosides within a DNA molecule. CHEBI:61748 (E)-oct-2-enal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61748 UBERON:0003928 digestive system duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003928 duct of digestive system|duct of gastrointestinal system|gastrointestinal system duct A duct that is part of a digestive system [Automatically generated definition]. UBERON:0003929 digestive tract epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003929 alimentary tract epithelium|gut epithelium|gastrodermis|epithelium of digestive tract|epithelial tissue of digestive tract|epithelium of gut|epithelial tissue of gut|digestive tract epithelial tissue|gut epithelial tissue An epithelium that lines the lumen of the digestive tract. UBERON:0003924 ventral pancreatic bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003924 pancreas ventral primordium duct bud|ventral pancreatic anlage|anterior pancreatic bud|ventral pancreas anlage|pancreas primordium ventral bud|anterior pancreatic anlage pancreatic bud that gives rise to the major pancreatic duct. UBERON:0003922 pancreatic epithelial bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003922 pancreatic buds|pancreas epithelium|pancreatic bud|pancreatic anlage The embryonic pancreas develops from two separate anlagen in the foregut epithelium, one dorsal and two ventral pancreatic buds[PMID]. UBERON:0003923 dorsal pancreatic bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003923 dorsal pancreas anlage|pancreas dorsal primordium duct bud|primary pancreatic bud|posterior pancreatic anlage|posterior pancreatic bud|pancreas primordium dorsal bud|dorsal pancreatic anlage pancreatic bud that gives rise to the accessory pancreatic duct. GO:0035504 regulation of myosin light chain kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035504 Any process that modulates the frequency, rate or extent of myosin light chain kinase activity. CHEBI:131876 hydroperoxyicosapentaenoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131876 GO:0035505 positive regulation of myosin light chain kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035505 Any process that activates or increases the frequency, rate or extent of myosin light chain kinase activity. CHEBI:131877 dihydroxyicosatetraenoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131877 GO:0035506 negative regulation of myosin light chain kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035506 Any process that stops, prevents, or reduces the frequency, rate or extent of myosin light chain kinase activity. CHEBI:131878 cholanic acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131878 CHEBI:46195 paracetamol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46195 GO:0035507 regulation of myosin-light-chain-phosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035507 Any process that modulates the frequency, rate or extent of myosin-light-chain-phosphatase activity. CHEBI:131879 cholanic acid conjugate anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131879 GO:0035508 positive regulation of myosin-light-chain-phosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035508 Any process that activates or increases the frequency, rate or extent of myosin-light-chain-phosphatase activity. GO:0035509 negative regulation of myosin-light-chain-phosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035509 Any process that stops, prevents, or reduces the frequency, rate or extent of myosin-light-chain-phosphatase activity. CHEBI:85721 diacylglycerol 28:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85721 CHEBI:131870 hydroxy monounsaturated fatty acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131870 CHEBI:131871 hydroxy polyunsaturated fatty acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131871 GO:0035500 MH2 domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035500 MAD homology 2 domain binding Interacting selectively and non-covalently with the MH2 (MAD homology 2) domain of a protein. The MH2 domain is found at the carboxy-terminus of MAD related proteins such as Smads. The MH2 domain mediates interaction with a wide variety of proteins and provides specificity and selectivity to Smad function and also is critical for mediating interactions in Smad oligomers. CHEBI:131872 hydroxy saturated fatty acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131872 GO:0035501 MH1 domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035501 MAD homology 1 domain binding Interacting selectively and non-covalently with the MH1 (MAD homology 1) domain of a protein. The MH1 domain is found at the amino terminus of MAD related proteins such as Smads and can mediate DNA binding in some proteins. Smads also use the MH1 domain to interact with some transcription factors. CHEBI:131873 EpETE(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131873 GO:0035502 metanephric part of ureteric bud development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035502 The development of the portion of the ureteric bud tube that contributes to the morphogenesis of the metanephros. CHEBI:131874 HEPE(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131874 CHEBI:131875 hydroperoxyicosatrienoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131875 GO:0035503 ureter part of ureteric bud development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035503 The development of the portion of the ureteric bud that contributes to the morphogenesis of the ureter. The ureter ureteric bud is the initial structure that forms the ureter. UBERON:0003931 diencephalic white matter biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003931 white matter of diencephalon|diencephalic tracts and commissures|predominantly white regional part of diencephalon|diencephalic tract/commissure White matter that is part of a diencephalon [Automatically generated definition]. UBERON:0003932 cartilage element of chondrocranium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003932 cartilage of chondrocranium|cartilaginous element of chondrocranium|neurocranium cartilage|chondrocranium cartilage A cartilage element of chondrocranium. Example: neurocranial trabecula. UBERON:0003930 atrioventricular canal endocardium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003930 AV canal endocardium|AVC endocardium|endocardium of atrioventricular canal|endocardium of AV canal Endocardium that is part of the atrioventricular canal[ZFA,vetted]. UBERON:0003917 arthropod fat body biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003917 fat body|fat body sensu invertebrata An insect gland dorsal to the insect gut, with a function analogous to that of the vertebrate liver. It is a storage organ for fats, glycogen and protein and is a major site of intermediary metabolism. UBERON:0003918 kidney mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003918 mesenchyme of kidney Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney[GO]. UBERON:0003915 endothelial tube biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003915 Any endothelium that has the quality of being cylindrical [Automatically generated definition]. UBERON:0003916 fat pad biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003916 fat body A mass of closely packed fat cells (adipose tissue) surrounded by fibrous tissue septa[TMD]. UBERON:0003913 tooth-like structure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003913 tooth-like organ hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food. CHEBI:155837 tripeptide zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_155837 UBERON:0003914 epithelial tube biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003914 epithelial or endothelial tube Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system. UBERON:0003911 choroid plexus epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003911 choroid plexus epithelial tissue|epithelial tissue of choroid plexus|epithelium of choroid plexus|epithelial tissue of chorioid plexus of cerebral hemisphere The epithelial component of the choroid plexus. Consists of cuboidal epithelial cells surrounding a core of capillaries and loose connective tissue. CHEBI:155834 phosphatidylethanolamine 34:1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_155834 UBERON:0003912 chitinous tooth biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003912 tooth-like structure composed of chitin. CHEBI:155835 phosphatidylethanolamine 34:2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_155835 CHEBI:131889 11-HEPE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131889 CHEBI:61760 D-mannosyl ditrans,polycis-undecaprenyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61760 CHEBI:61761 D-mannosyl ditrans,polycis-undecaprenyl phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61761 UBERON:0003920 venous blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003920 segment of venous tree organ|venous tree organ segment A blood vessel that carries blood from the capillaries toward the heart UBERON:0003921 pancreas primordium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003921 pancreatic endoderm|pancreatic primordium|pancreatic anlage|primordial pancreas embryonic structure that develops into pancreatic bud. UBERON:0003906 cardiac jelly biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003906 heart cardiac jelly Portion of extracellular matrix between the myocardium and the endocardium. The cardiac jelly plays a central role in the septation of the heart and comprises most of the thickness of the heart wall at early stages, but disappears as the heart differentiates. UBERON:0003907 left atrioventricular canal biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003907 left atrio-ventricular canal|left AVC An atrioventricular canal that is in the left side of a atrioventricular region. UBERON:0003902 retinal neural layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003902 stratum nervosum (retina)|stratum nervosum retinae|neural retina|neuroretina|neural retinal epithelium|neural layer of retina The part of the retina that contains neurons and photoreceptor cells[GO]. UBERON:0003903 bursa of Fabricius biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003903 An epithelial and lymphoid organ that develops as a dorsal diverticulum of the proctodeal region of the cloaca in birds. The luminal (interior) surface of the bursa is plicated with as many as 15 primary and 7 secondary plicae or folds. These plicae have hundreds of bursal follicles containing follicle-associated epithelial cells, lymphocytes, macrophages, and plasma cells. Lymphoid stem cells migrate from the fetal liver to the bursa during ontogeny. In the bursa, these stem cells acquire the characteristics of mature, immunocompetent B cells[WP]. The bursa is an organ found in birds involved in B cell differentiation[GO]. CHEBI:131856 3,5-dimethylorsellinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131856 CHEBI:131857 (3R)-farnesyl-2,3,5-trimethyl-6-oxido-4-oxocyclohexa-1,5-diene-1-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131857 CHEBI:131858 HETE anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131858 CHEBI:131859 oxo-ETE anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131859 UBERON:0003908 right atrioventricular canal biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003908 right atrio-ventricular canal|right AVC An atrioventricular canal that is in the right side of a atrioventricular region. UBERON:0003909 sinusoid biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003909 sinusoidal blood vessel endothelium|sinusoidal endothelium|sinusoidal capillary|sinusoidal blood vessel|endothelium of irregular blood filled space small blood vessel similar to a capillary but with a fenestrated endothelium. Sinusoids are found in the liver, lymphoid tissue, endocrine organs, and hematopoietic organs such as the bone marrow and the spleen. Sinusoids found within terminal villi of the placenta are not comparable to these; they possess a continuous endothelium and complete basal lamina[WP]. CHEBI:61777 terpene glycoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61777 CHEBI:61778 triterpenoid saponin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61778 CHEBI:131865 EET(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131865 CHEBI:131867 hydroxydocosahexaenoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131867 CHEBI:131868 HPDHE(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131868 CHEBI:131869 hydroxy monounsaturated fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131869 CHEBI:131860 octadecanoid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131860 CHEBI:131861 HODE(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131861 CHEBI:131862 HPODE(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131862 CHEBI:131863 docosanoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131863 CHEBI:131864 docosanoid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131864 GO:1901569 fatty acid derivative catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901569 fatty acid derivative breakdown|fatty acid derivative catabolism|fatty acid derivative degradation The chemical reactions and pathways resulting in the breakdown of fatty acid derivative. GO:1901567 fatty acid derivative binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901567 Interacting selectively and non-covalently with fatty acid derivative. GO:1901568 fatty acid derivative metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901568 fatty acid derivative metabolism The chemical reactions and pathways involving fatty acid derivative. GO:1901565 organonitrogen compound catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901565 organonitrogen compound catabolism|organonitrogen compound degradation|organonitrogen compound breakdown The chemical reactions and pathways resulting in the breakdown of organonitrogen compound. GO:1901566 organonitrogen compound biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901566 organonitrogen compound anabolism|organonitrogen compound synthesis|organonitrogen compound formation|organonitrogen compound biosynthesis The chemical reactions and pathways resulting in the formation of organonitrogen compound. GO:0060470 positive regulation of cytosolic calcium ion concentration involved in egg activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060470 elevation of cytosolic calcium ion concentration involved in egg activation The process that increases the concentration of calcium ions in the cytosol after fertilization or the physiological activation of an egg. GO:1901563 response to camptothecin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901563 response to CPT Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a camptothecin stimulus. GO:0060471 cortical granule exocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060471 cortical reaction|cortical granule release The process of secretion by a cell that results in the release of intracellular molecules contained within a cortical granule by fusion of the vesicle with the plasma membrane of a cell. A cortical granule is a specialized secretory vesicle that is released during egg activation that changes the surface of the egg to prevent polyspermy. GO:1901564 organonitrogen compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901564 organonitrogen compound metabolism The chemical reactions and pathways involving organonitrogen compound. GO:1901561 response to benomyl biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901561 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benomyl stimulus. GO:0060472 positive regulation of cortical granule exocytosis by positive regulation of cytosolic calcium ion concentration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060472 positive regulation of cortical granule exocytosis by elevation of cytosolic calcium ion concentration Any process that activates or increases the frequency, rate or extent of cortical granule exocytosis by directing movement of calcium ions (Ca2+) into the cytosol. GO:1901562 response to paraquat biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901562 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paraquat stimulus. GO:0060473 cortical granule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0060473 cortical vesicle A secretory vesicle that is stored under the cell membrane of an egg. These vesicles fuse with the egg plasma membrane as part of egg activation and are part of the block to polyspermy. GO:0060474 positive regulation of flagellated sperm motility involved in capacitation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060474 positive regulation of sperm motility involved in capacitation The process in which the controlled movement of a flagellated sperm cell is initiated as part of the process required for flagellated sperm to reach fertilization competence. GO:1901570 fatty acid derivative biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901570 fatty acid derivative biosynthesis|fatty acid derivative anabolism|fatty acid derivative synthesis|fatty acid derivative formation The chemical reactions and pathways resulting in the formation of fatty acid derivative. GO:0060475 positive regulation of actin filament polymerization involved in acrosome reaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060475 positive regulation of actin polymerization involved in acrosome reaction Any process that activates or increases the frequency, rate or extent of actin polymerization as part of the acrosome reaction. GO:1901571 fatty acid derivative transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901571 The directed movement of a fatty acid derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0060476 protein localization involved in acrosome reaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060476 protein localisation involved in acrosome reaction The actin-based process in which a protein is transported to, or maintained in, a specific location in the sperm as part of the acrosome reaction. GO:0060477 obsolete peptidyl-serine phosphorylation involved in acrosome reaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060477 OBSOLETE. The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine that is part of the acrosome reaction. GO:0060478 acrosomal vesicle exocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060478 acrosome exocytosis|acrosomal granule exocytosis The calcium ion regulated exocytosis which results in fusion of the acrosomal vesicle with the plasma membrane of the sperm as part of the acrosome reaction. GO:0060479 lung cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060479 pulmonary cell differentiation The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate. GO:1901578 negative regulation of alkane biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901578 inhibition of alkane anabolism|down regulation of alkane formation|inhibition of alkane synthesis|negative regulation of alkane biosynthesis|down-regulation of alkane biosynthetic process|down-regulation of alkane biosynthesis|inhibition of alkane formation|inhibition of alkane biosynthetic process|down-regulation of alkane anabolism|negative regulation of alkane anabolism|down-regulation of alkane synthesis|inhibition of alkane biosynthesis|negative regulation of alkane synthesis|down-regulation of alkane formation|negative regulation of alkane formation|downregulation of alkane anabolism|down regulation of alkane biosynthetic process|down regulation of alkane biosynthesis|down regulation of alkane anabolism|downregulation of alkane synthesis|downregulation of alkane biosynthesis|downregulation of alkane biosynthetic process|downregulation of alkane formation|down regulation of alkane synthesis Any process that stops, prevents or reduces the frequency, rate or extent of alkane biosynthetic process. GO:1901579 positive regulation of alkane biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901579 upregulation of alkane synthesis|positive regulation of alkane biosynthesis|activation of alkane biosynthetic process|upregulation of alkane formation|up-regulation of alkane anabolism|activation of alkane biosynthesis|up-regulation of alkane synthesis|up-regulation of alkane biosynthesis|up-regulation of alkane biosynthetic process|activation of alkane anabolism|up-regulation of alkane formation|activation of alkane synthesis|positive regulation of alkane anabolism|up regulation of alkane anabolism|activation of alkane formation|upregulation of alkane biosynthesis|positive regulation of alkane synthesis|upregulation of alkane biosynthetic process|up regulation of alkane synthesis|positive regulation of alkane formation|up regulation of alkane formation|upregulation of alkane anabolism|up regulation of alkane biosynthesis|up regulation of alkane biosynthetic process Any process that activates or increases the frequency, rate or extent of alkane biosynthetic process. GO:1901576 organic substance biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901576 organic molecular entity formation|organic molecular entity biosynthetic process|organic molecular entity biosynthesis|organic substance anabolism|organic substance biosynthesis|organic molecular entity anabolism|organic substance synthesis|organic molecular entity synthesis|organic substance formation The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon. GO:1901577 regulation of alkane biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901577 regulation of alkane anabolism|regulation of alkane biosynthesis|regulation of alkane synthesis|regulation of alkane formation Any process that modulates the frequency, rate or extent of alkane biosynthetic process. GO:1901574 obsolete chemical substance biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901574 chemical substance biosynthetic process|chemical substance synthesis|chemical substance formation|chemical substance biosynthesis|chemical substance anabolism OBSOLETE. The chemical reactions and pathways resulting in the formation of chemical substance. GO:0060460 left lung morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060460 The process in which anatomical structures of the left lung are generated and organized. GO:1901575 organic substance catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901575 organic molecular entity catabolic process|organic substance degradation|organic molecular entity degradation|organic substance breakdown|organic molecular entity breakdown|organic molecular entity catabolism|organic substance catabolism The chemical reactions and pathways resulting in the breakdown of an organic substance, any molecular entity containing carbon. GO:1901572 obsolete chemical substance metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901572 chemical substance metabolic process|chemical substance metabolism OBSOLETE. The chemical reactions and pathways involving chemical substance. GO:0060461 right lung morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060461 The process in which anatomical structures of the right lung are generated and organized. GO:1901573 obsolete chemical substance catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901573 chemical substance catabolic process|chemical substance catabolism|chemical substance degradation|chemical substance breakdown OBSOLETE. The chemical reactions and pathways resulting in the breakdown of chemical substance. GO:0060462 lung lobe development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060462 The biological process whose specific outcome is the progression of a lung lobe from an initial condition to its mature state. This process begins with the formation of a lung lobe by branching morphogenesis and ends with the mature structure. A lung lobe is one of the rounded projections that compose the lung. GO:0060463 lung lobe morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060463 The process in which the anatomical structures of a lung lobe are generated and organized. A lung lobe is a projection that extends from the lung. GO:1901581 negative regulation of telomeric RNA transcription from RNA pol II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901581 down regulation of telomeric RNA transcription from Pol II promoter|inhibition of telomeric RNA transcription from Pol II promoter|down-regulation of telomeric RNA transcription from RNA pol II promoter|down-regulation of telomeric RNA transcription from Pol II promoter|negative regulation of telomeric RNA transcription from Pol II promoter|downregulation of telomeric RNA transcription from RNA pol II promoter|down regulation of telomeric RNA transcription from RNA pol II promoter|downregulation of telomeric RNA transcription from Pol II promoter|inhibition of telomeric RNA transcription from RNA pol II promoter Any process that stops, prevents or reduces the frequency, rate or extent of telomeric RNA transcription from RNA pol II promoter. GO:0035496 lipopolysaccharide-1,5-galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035496 UDP-D-galactose:(glucosyl)lipopolysaccharide-1,5-D-galactosyltransferase|LPS-1,5-galactosyltransferase activity Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,5 alpha-D-galactosyl-lipopolysaccharide. GO:0035497 cAMP response element binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035497 cyclic AMP response element binding|cyclic-AMP-responsive element binding|CRE binding|cAMP-responsive element binding|cyclic-AMP response element binding Interacting selectively and non-covalently with the cyclic AMP response element (CRE), a short palindrome-containing sequence found in the promoters of genes whose expression is regulated in response to cyclic AMP. GO:1901582 positive regulation of telomeric RNA transcription from RNA pol II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901582 upregulation of telomeric RNA transcription from RNA pol II promoter|upregulation of telomeric RNA transcription from Pol II promoter|up-regulation of telomeric RNA transcription from RNA pol II promoter|activation of telomeric RNA transcription from RNA pol II promoter|up-regulation of telomeric RNA transcription from Pol II promoter|activation of telomeric RNA transcription from Pol II promoter|up regulation of telomeric RNA transcription from RNA pol II promoter|positive regulation of telomeric RNA transcription from Pol II promoter|up regulation of telomeric RNA transcription from Pol II promoter Any process that activates or increases the frequency, rate or extent of telomeric RNA transcription from RNA pol II promoter. GO:0060464 lung lobe formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060464 The developmental process pertaining to the initial formation of a lung lobe from unspecified parts. This process begins with the specific processes that contribute to the appearance of the lobe and ends when the structural rudiment is recognizable. A lung lobe is a projection that extends from the lung. GO:0060465 pharynx development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060465 pharyngeal development The biological process whose specific outcome is the progression of a pharynx from an initial condition to its mature state. The pharynx is the part of the digestive system immediately posterior to the mouth. GO:0035498 carnosine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035498 carnosine metabolism The chemical reactions and pathways involving the dipeptide beta-alanyl-L-histidine (carnosine). GO:1901580 regulation of telomeric RNA transcription from RNA pol II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901580 regulation of telomeric RNA transcription from Pol II promoter Any process that modulates the frequency, rate or extent of telomeric RNA transcription from RNA pol II promoter. GO:0035499 carnosine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035499 carnosine anabolism|carnosine synthesis|carnosine formation|carnosine biosynthesis The chemical reactions and pathways resulting in the formation of the dipeptide beta-alanyl-L-histidine (carnosine). GO:0060466 activation of meiosis involved in egg activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060466 reactivation of meiosis after fertilization|resumption of meiosis involved in egg activation Any process that starts the inactive process of meiosis in an egg after the egg has been fertilized or physiologically activated. Eggs generally arrest in meiosis and complete the process after activation. GO:0060467 negative regulation of fertilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060467 Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy). GO:0060468 prevention of polyspermy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060468 negative regulation of fertilization involved in egg activation|polyspermy block The negative regulation of fertilization process that takes place as part of egg activation, ensuring that only a single sperm fertilizes the egg. GO:0060469 positive regulation of transcription involved in egg activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060469 activation of the egg genome|activation of the maternal genome Any process that increases the rate, frequency or extent of transcription as a part of the process of egg activation. GO:0035490 regulation of leukotriene production involved in inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035490 Any process that modulates the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response. GO:0035491 positive regulation of leukotriene production involved in inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035491 Any process that increases the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response. GO:0035492 negative regulation of leukotriene production involved in inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035492 Any process that decreases the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response. GO:0035493 SNARE complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035493 The aggregation, arrangement and bonding together of a set of components to form a SNARE complex, a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. GO:0035494 SNARE complex disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035494 The disaggregation of the SNARE protein complex into its constituent components. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. GO:0035495 regulation of SNARE complex disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035495 Any process that modulates the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. GO:1901589 axon microtubule bundle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1901589 NIF_Subcellular:sao707332678 axon microtubule fascicle|microtubule bundle of axon|microtubule fascicle of axon An arrangement of closely apposed microtubules running parallel to each other in the axon hillock and initial segment. GO:1901587 positive regulation of acid-sensing ion channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901587 positive regulation of ASIC activity|up-regulation of acid-sensing ion channel activity|activation of ASIC activity|up-regulation of ASIC activity|upregulation of acid-sensing ion channel activity|upregulation of ASIC activity|up regulation of acid-sensing ion channel activity|activation of acid-sensing ion channel activity|up regulation of ASIC activity Any process that activates or increases the frequency, rate or extent of acid-sensing ion channel activity. GO:0060490 lateral sprouting involved in lung morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060490 The process in which a branch forms along the side of the lung epithelial tube. GO:1901588 dendritic microtubule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1901588 NIF_Subcellular:sao110773650 microtubulus of dendrite|microtubule of dendrite Any microtubule in a dendrite, a neuron projection. GO:0060491 regulation of cell projection assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060491 regulation of cell projection formation Any process that modulates the rate, frequency, or extent of cell projection assembly. GO:1901585 regulation of acid-sensing ion channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901585 regulation of ASIC activity Any process that modulates the frequency, rate or extent of acid-sensing ion channel activity. GO:0060492 lung induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060492 The close range interaction of two or more cells or tissues that causes the cells of the foregut to change their fates and specify the development of the lung. GO:0060493 mesenchymal-endodermal cell signaling involved in lung induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060493 mesenchymal-endodermal cell signalling involved in lung induction Any process that mediates the transfer of information from a mesenchymal cell to an endodermal cell in the foregut and contributes to the formation of the lung bud. GO:1901586 negative regulation of acid-sensing ion channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901586 down-regulation of ASIC activity|negative regulation of ASIC activity|inhibition of acid-sensing ion channel activity|inhibition of ASIC activity|down regulation of acid-sensing ion channel activity|downregulation of acid-sensing ion channel activity|down regulation of ASIC activity|downregulation of ASIC activity|down-regulation of acid-sensing ion channel activity Any process that stops, prevents or reduces the frequency, rate or extent of acid-sensing ion channel activity. GO:1901583 tetrapeptide transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901583 tetrapeptide membrane transport The directed movement of tetrapeptide across a membrane. GO:0060494 inductive mesenchymal-endodermal cell signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060494 inductive mesenchymal-endodermal cell signalling Any process that mediates the transfer of information from a mesenchymal cell to an endodermal cell changing the fate of the endodermal cell. GO:1901584 tetrapeptide transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901584 Enables the transfer of tetrapeptide from one side of a membrane to the other. GO:0060495 cell-cell signaling involved in lung development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060495 cell-cell signalling involved in lung development Any process that mediates the transfer of information from one cell to another and contributes to the progression of the lung, from its initial state to the mature structure. GO:1901592 negative regulation of double-strand break repair via break-induced replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901592 inhibition of double-strand break repair via break-induced replication|down-regulation of double-strand break repair via break-induced replication|downregulation of double-strand break repair via break-induced replication|down regulation of double-strand break repair via break-induced replication Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via break-induced replication. GO:0060496 mesenchymal-epithelial cell signaling involved in lung development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060496 mesenchymal-epithelial cell signalling involved in lung development Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell and contributes to the development of the lung. GO:0035485 adenine/guanine mispair binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035485 A/G mispair binding|G/A mispair binding|guanine-adenine mispair binding Interacting selectively and non-covalently with double-stranded DNA containing an A/G mispair. GO:1901593 response to GW 7647 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901593 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a GW 7647 stimulus. GO:0035486 cytosine/cytosine mispair binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035486 C/C mispair binding Interacting selectively and non-covalently with double-stranded DNA containing a C/C mispair. GO:0060497 mesenchymal-endodermal cell signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060497 mesenchymal-endodermal cell signalling Any process that mediates the transfer of information between a mesenchymal cell and an endodermal cell. GO:0035487 thymine/thymine mispair binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035487 T/T mispair binding Interacting selectively and non-covalently with double-stranded DNA containing a T/T mispair. GO:0060498 retinoic acid receptor signaling pathway involved in lung bud formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060498 retinoic acid receptor signalling pathway involved in lung bud formation The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands contributing to the formation of the primary lung bud. GO:0035488 cytosine/thymine mispair binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035488 T/C mispair binding|thymine/cytosine mispair binding|C/T mispair binding Interacting selectively and non-covalently with double-stranded DNA containing a C/T mispair. GO:1901591 regulation of double-strand break repair via break-induced replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901591 Any process that modulates the frequency, rate or extent of double-strand break repair via break-induced replication. GO:0060499 fibroblast growth factor receptor signaling pathway involved in lung induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060499 fibroblast growth factor receptor signalling pathway involved in lung induction The series of molecular signals generated as a consequence of a fibroblast growth factor-type receptor binding to one of its physiological ligands resulting in the formation of the lung bud along the lateral-esophageal sulcus. GO:0035489 guanine/guanine mispair binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035489 G/G mispair binding Interacting selectively and non-covalently with double-stranded DNA containing a G/G mispair. GO:0035480 regulation of Notch signaling pathway involved in heart induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035480 regulation of Notch signalling pathway involved in heart induction Any process that modulates the frequency, rate or extent of the series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to heart induction. GO:0035481 positive regulation of Notch signaling pathway involved in heart induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035481 positive regulation of Notch signalling pathway involved in heart induction Any process that activates or increases the frequency, rate or extent of the series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to heart induction. GO:0035482 gastric motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035482 The spontaneous peristaltic movements of the stomach that aid in digestion, moving food through the stomach and out through the pyloric sphincter into the duodenum. GO:0035483 gastric emptying biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035483 The process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum. GO:0035484 adenine/adenine mispair binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035484 A/A mispair binding Interacting selectively and non-covalently with double-stranded DNA containing an A/A mispair. GO:1901598 (-)-pinoresinol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901598 (-)-pinoresinol metabolism The chemical reactions and pathways involving (-)-pinoresinol. GO:1901599 (-)-pinoresinol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901599 (-)-pinoresinol anabolism|(-)-pinoresinol synthesis|(-)-pinoresinol formation|(-)-pinoresinol biosynthesis The chemical reactions and pathways resulting in the formation of (-)-pinoresinol. GO:0060480 lung goblet cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060480 pulmonary goblet cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a lung goblet cell. A goblet cell is a cell of the epithelial lining that produces and secretes mucins. GO:0060481 lobar bronchus epithelium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060481 The biological process whose specific outcome is the progression of a lobar bronchus epithelium from an initial condition to its mature state. This process begins with the formation of the lobar bronchus epithelium and ends with the mature structure. The lobar bronchus epithelium is the tissue made up of epithelial cells that lines the inside of the lobar bronchus. GO:1901596 response to reversine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901596 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reversine stimulus. GO:1901597 response to carbendazim biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901597 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbendazim stimulus. GO:0060482 lobar bronchus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060482 The biological process whose specific outcome is the progression of a lobar bronchus from an initial condition to its mature state. This process begins with the formation of the lobar bronchus and ends with the mature structure. The lobar bronchus is the major airway within the respiratory tree that starts by division of the principal bronchi on both sides and ends at the point of its own subdivision into tertiary or segmental bronchi. GO:1901594 response to capsazepine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901594 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a capsazepine stimulus. GO:0060483 lobar bronchus mesenchyme development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060483 The biological process whose specific outcome is the progression of a lobar bronchus mesenchyme from an initial condition to its mature state. This process begins with the formation of the lobar bronchus mesenchyme and ends with the mature structure. The lobar bronchus mesenchyme is the mass of tissue composed of mesenchymal cells in the lobar bronchus. GO:1901595 response to hesperadin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901595 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hesperadin stimulus. GO:0060484 lung-associated mesenchyme development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060484 lung mesenchyme development|pulmonary mesenchyme development The biological process whose specific outcome is the progression of a lung-associated mesenchyme from an initial condition to its mature state. This process begins with the formation of lung-associated mesenchyme and ends with the mature structure. Lung-associated mesenchyme is the tissue made up of loosely connected mesenchymal cells in the lung. GO:0060485 mesenchyme development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060485 mesenchymal development The process whose specific outcome is the progression of a mesenchymal tissue over time, from its formation to the mature structure. A mesenchymal tissue is made up of loosely packed stellate cells. GO:0035474 selective angioblast sprouting biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035474 The segregation of angioblasts into discrete arterial and venous vessels from one common precursor vessel. GO:0060486 club cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060486 Clara cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a club cell. A club cell is an unciliated epithelial cell found in the respiratory and terminal bronchioles. GO:0035475 angioblast cell migration involved in selective angioblast sprouting biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035475 The directional migration of angioblast cells as part of selective angioblast sprouting, which results in angioblast segregation into arterial and venous populations. GO:0035476 angioblast cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035476 The orderly movement of angioblasts, cells involved in blood vessel morphogenesis. GO:0060487 lung epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060487 pulmonary epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell that contributes to the epithelium of the lung. GO:0035477 regulation of angioblast cell migration involved in selective angioblast sprouting biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035477 Any process that modulates the frequency, rate or extent of angioblast cell migration involved in selective angioblast sprouting. GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060488 perpendicular dichotomous subdivision of terminal units involved in lung branching morphogenesis The process in which a lung bud bifurcates perpendicular to the plane of the previous bud. GO:0060489 planar dichotomous subdivision of terminal units involved in lung branching morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060489 The process in which a lung bud bifurcates parallel to the plane of the previous bud. GO:0035478 chylomicron binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035478 Interacting selectively and non-covalently with a chylomicron, a large lipoprotein particle (diameter 75-1200 nm) composed of a central core of triglycerides and cholesterol surrounded by a protein-phospholipid coating. The proteins include one molecule of apolipoprotein B-48 and may include a variety of apolipoproteins, including APOAs, APOCs and APOE. GO:0035479 angioblast cell migration from lateral mesoderm to midline biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035479 The directed movement of angioblasts from the lateral mesoderm to the midline which occurs as part of the formation of the early midline vasculature. GO:0035470 positive regulation of vascular wound healing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035470 Any process that increases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature. GO:0035471 luteinizing hormone signaling pathway involved in ovarian follicle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035471 luteinizing hormone signalling pathway involved in ovarian follicle development The series of molecular signals initiated by luteinizing hormone binding to a receptor, where the activated receptor signals via downstream effectors that contribute to progression of the ovarian follicle over time, from its formation to the mature structure. GO:0035472 choriogonadotropin hormone receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035472 chorionic gonadotropin hormone receptor|chorio-gonadotrophin receptor activity|CG receptor activity Combining with the choriogonadotropin hormone to initiate a change in cell activity. GO:0035473 lipase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035473 Interacting selectively and non-covalently with any lipase. CHEBI:141282 sulfoquinovosyldiacylglycerol 36:6 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_141282 CHEBI:141283 (6E)-nerolidol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_141283 NCBITaxon:2301119 Rhabditomorpha organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_2301119 CHEBI:141280 sulfoquinovosyldiacylglycerol 36:4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_141280 CHEBI:141281 sulfoquinovosyldiacylglycerol 36:5 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_141281 NCBITaxon:2301116 Rhabditina organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_2301116 GO:0035463 transforming growth factor beta receptor signaling pathway involved in determination of left/right asymmetry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035463 TGF-beta receptor signaling pathway involved in determination of left/right asymmetry|TGF-beta receptor signalling pathway involved in determination of left/right asymmetry|TGFbeta receptor signalling pathway involved in determination of left/right asymmetry|transforming growth factor beta receptor signalling pathway involved in determination of left/right asymmetry|TGFbeta receptor signaling pathway involved in determination of left/right asymmetry A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to determination of organismal asymmetry with respect to the left and right halves. GO:0035464 regulation of transforming growth factor receptor beta signaling pathway involved in determination of left/right asymmetry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035464 regulation of TGFbeta receptor signaling pathway involved in determination of left/right asymmetry|regulation of transforming growth factor beta receptor signalling pathway involved in determination of left/right asymmetry|regulation of TGF-beta receptor signalling pathway involved in determination of left/right asymmetry|regulation of TGF-beta receptor signaling pathway involved in determination of left/right asymmetry|regulation of TGFbeta receptor signalling pathway involved in determination of left/right asymmetry Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway that is involved in the determination of organismal asymmetry with regard to its left and right halves. GO:0035465 obsolete regulation of transforming growth factor beta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035465 regulation of TGFbeta receptor signalling pathway involved in determination of lateral mesoderm left/right asymmetry|regulation of transforming growth factor beta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry|regulation of TGF-beta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry|regulation of TGF-beta receptor signalling pathway involved in determination of lateral mesoderm left/right asymmetry|regulation of transforming growth factor beta receptor signalling pathway involved in determination of lateral mesoderm left/right asymmetry|regulation of TGFbeta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry OBSOLETE. Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway that is involved in the determination of the lateral plate mesoderm with respect to its left and right halves. GO:0035466 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035466 GO:0035467 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035467 GO:0035468 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035468 GO:0035469 determination of pancreatic left/right asymmetry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035469 Determination of the asymmetric location of the pancreas with respect to the left and right halves of the organism. GO:0035460 L-ascorbate 6-phosphate lactonase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035460 RHEA:28803 Catalysis of the reaction: L-ascorbate 6-phosphate + H2O = 3-keto-L-gulonate 6-phosphate. GO:0035461 vitamin transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035461 vitamin membrane transport The process in which a vitamin is transported across a membrane. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. GO:0035462 determination of left/right asymmetry in diencephalon biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035462 The establishment of the diencephalon with respect to the left and right halves. CHEBI:141271 sulfoquinovosyldiacylglycerol 32:3 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_141271 CHEBI:141272 sulfoquinovosyldiacylglycerol 34:0 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_141272 CHEBI:141270 sulfoquinovosyldiacylglycerol 32:1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_141270 CHEBI:141279 sulfoquinovosyldiacylglycerol 36:3 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_141279 CHEBI:141277 sulfoquinovosyldiacylglycerol 34:5 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_141277 CHEBI:141278 sulfoquinovosyldiacylglycerol 36:2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_141278 CHEBI:141275 sulfoquinovosyldiacylglycerol 34:3 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_141275 CHEBI:141276 sulfoquinovosyldiacylglycerol 34:4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_141276 CHEBI:141273 sulfoquinovosyldiacylglycerol 34:1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_141273 CHEBI:141274 sulfoquinovosyldiacylglycerol 34:2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_141274 GO:0035452 extrinsic component of plastid membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035452 extrinsic to plastid membrane|peripheral to plastid membrane The component of a plastid membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:0035453 extrinsic component of plastid inner membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035453 extrinsic to plastid inner membrane|peripheral to plastid inner membrane The component of a plastid inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:0035454 extrinsic component of stromal side of plastid inner membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035454 extrinsic to stromal side of plastid inner membrane|peripheral to stromal side of plastid inner membrane|extrinsic to stromal leaflet of plastid inner membrane The component of a plastid inner membrane consisting of gene products and protein complexes that are loosely bound to its stromal surface, but not integrated into the hydrophobic region. GO:0035455 response to interferon-alpha biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035455 response to lymphoblastoid interferon|response to interferon alfa-n3|response to interferon alfa-n1|response to lymphoblast interferon|response to leukocyte interferon Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-alpha stimulus. Interferon-alpha is a type I interferon. GO:0035456 response to interferon-beta biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035456 response to fiblaferon|response to interferon beta|response to beta-1 interferon|response to fibroblast interferon Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon. GO:0035457 cellular response to interferon-alpha biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035457 cellular response to leukocyte interferon|cellular response to interferon alfa-n3|cellular response to interferon alfa-n1|cellular response to lymphoblastoid interferon|cellular response to lymphoblast interferon Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-alpha stimulus. Interferon-alpha is a type I interferon. GO:0035458 cellular response to interferon-beta biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035458 cellular response to beta-1 interferon|cellular response to fibroblast interferon|cellular response to fiblaferon Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon. GO:0035459 vesicle cargo loading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035459 cargo loading into vesicle|cargo selection The formation of a macromolecular complex between the coat proteins and proteins and/or lipoproteins that are going to be transported by a vesicle. GO:0035450 extrinsic component of lumenal side of plastid thylakoid membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035450 extrinsic to lumenal side of plastid thylakoid membrane|peripheral to lumenal side of plastid thylakoid membrane|extrinsic to lumenal leaflet of plastid thylakoid membrane The component of a plastid thylakoid membrane consisting of gene products and protein complexes that are loosely bound to its lumenal surface, but not integrated into the hydrophobic region. GO:0035451 extrinsic component of stromal side of plastid thylakoid membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035451 extrinsic to stromal side of plastid thylakoid membrane|peripheral to stromal side of plastid thylakoid membrane|extrinsic to stromal leaflet of plastid thylakoid membrane The component of a plastid thylakoid membrane consisting of gene products and protein complexes that are loosely bound to its stromal surface, but not integrated into the hydrophobic region. GO:0035449 extrinsic component of plastid thylakoid membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035449 peripheral to plastid thylakoid membrane|extrinsic to plastid thylakoid membrane The component of a plastid thylakoid membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:0035441 cell migration involved in vasculogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035441 The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form de novo blood vessels and tubes. GO:0035442 dipeptide transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035442 dipeptide membrane transport The directed movement of a dipeptide across a membrane by means of some agent such as a transporter or pore. A dipeptide is a combination of two amino acids linked together by a peptide (-CO-NH-) bond. GO:0035443 tripeptide transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035443 tripeptide membrane transport The directed movement of a tripeptide across a membrane by means of some agent such as a transporter or pore. A tripeptide is a compound containing three amino acids linked together by peptide bonds. GO:0035444 nickel cation transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035444 nickel cation membrane transport The directed movement of nickel (Ni) cations across a membrane by means of some agent such as a transporter or pore. GO:0035445 borate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035445 borate membrane transport|boron transmembrane transport The process in which borate is transported across a membrane. Borate is the anion (BO3)3-; boron is a group 13 element, with properties which are borderline between metals and non-metals. GO:0035446 cysteine-glucosaminylinositol ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035446 MetaCyc:RXN1G-4|EC:6.3.1.13|RHEA:26176 desacetylmycothiol synthase|L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase|MshC ligase Catalysis of the reaction: 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol + L-cysteine + ATP = 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside + AMP + diphosphate + 2 H+. 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol is also known as glucosaminyl-inositol or GlcN-Ins, and 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside as desacetylmycothiol or Cys-GlcN-Ins. GO:0035447 mycothiol synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035447 MetaCyc:MONOMER-9684 acetyl-CoA:Cys-GlcN-Ins acetyltransferase Catalysis of the reaction: 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside + acetyl-CoA = mycothiol + coenzyme A + H+. Mycothiol is also known as AcCys-GlcN-Ins and 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside as Cys-GlcN-Ins or desacetylmycothiol. GO:0035448 extrinsic component of thylakoid membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035448 extrinsic to thylakoid membrane|peripheral to thylakoid membrane The component of a thylakoid membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:0035440 tuberculosinol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035440 MetaCyc:PWY-5935 tuberculosinol biosynthesis|halima-5,6,dien-15-ol biosynthetic process|halima-5,6,dien-15-ol biosynthesis The chemical reactions and pathways resulting in the formation of tuberculosinol (halima-5,6,dien-15-ol), a secondary metabolite in Mycobacteria. GO:0035438 cyclic-di-GMP binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035438 c-di-GMP binding|3',5'-cyclic di-GMP binding|cyclic dinucleotide di-GMP binding Interacting selectively and non-covalently with cyclic-di-GMP, cyclic dimeric guanosine monophosphate. GO:0035439 halimadienyl-diphosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035439 EC:5.5.1.16|RHEA:25621 halimadienyl diphosphate synthase activity|halima-5(6),13-dien-15-yl-diphosphate lyase (cyclizing) Catalysis of the reaction: geranylgeranyl diphosphate = halima-5(6),13-dien-15-yl diphosphate. GO:0035430 regulation of gluconate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035430 regulation of gluconate transport|regulation of gluconate membrane transport Any process that modulates the frequency, rate or extent of the directed movement of a gluconate across a membrane by means of some agent such as a transporter or pore. GO:0035431 negative regulation of gluconate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035431 negative regulation of gluconate transport|inhibition of gluconate transport|negative regulation of gluconate membrane transport|down regulation of gluconate transport|downregulation of gluconate transport|down-regulation of gluconate transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of gluconate across a membrane by means of some agent such as a transporter or pore. GO:0035432 positive regulation of gluconate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035432 up-regulation of gluconate transport|induction of gluconate transport|upregulation of gluconate transport|positive regulation of gluconate membrane transport|up regulation of gluconate transport|activation of gluconate transport|stimulation of gluconate transport|positive regulation of gluconate transport Any process that activates or increases the frequency, rate or extent of the directed movement of gluconate across a membrane by means of some agent such as a transporter or pore. GO:0035433 acetate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035433 acetate membrane transport The process in which acetate is transported across a membrane. Acetate is the 2-carbon carboxylic acid ethanoic acid. GO:0035434 copper ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035434 copper cation transmembrane transport|copper ion membrane transport The directed movement of copper cation across a membrane. CHEBI:61702 dinoflagellate luciferin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61702 GO:0035435 phosphate ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035435 phosphate ion membrane transport The process in which a phosphate is transported across a membrane. CHEBI:61703 nonclassic icosanoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61703 CHEBI:61700 (+)-valencene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61700 GO:0035436 triose phosphate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035436 triose phosphate membrane transport|triose phosphate transmembrane transport The process in which triose phosphate (glyceraldehyde 3-phosphate) is transported across a membrane. Glyceraldehyde 3-phosphate is any organic three carbon compound phosphate ester. GO:0035437 maintenance of protein localization in endoplasmic reticulum biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035437 maintenance of protein location in endoplasmic reticulum|retention of protein in ER|protein-endoplasmic reticulum retention|maintenance of protein localization in ER|retention of protein in endoplasmic reticulum|maintenance of protein localisation in endoplasmic reticulum|maintenance of protein location in ER|protein-ER retention Any process in which a protein is maintained in the endoplasmic reticulum and prevented from moving elsewhere. These include sequestration within the endoplasmic reticulum, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the endoplasmic reticulum. CHEBI:61701 L-ascorbic acid 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61701 CHEBI:61706 dinoflagellate luciferin(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61706 CHEBI:61707 oxidized dinoflagellate luciferin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61707 CHEBI:61704 oxoicosatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61704 CHEBI:61705 3-demethylubiquinol-8 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61705 CHEBI:61708 oxidized dinoflagellate luciferin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61708 CHEBI:22102 UDP-D-glucosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22102 CHEBI:36749 dipyrrins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36749 CHEBI:36742 p-menthan-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36742 CHEBI:36743 germacrene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36743 CHEBI:12777 vitamin A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_12777 CHEBI:36740 alpha-pinene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36740 CHEBI:36741 phycoerythrobilin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36741 CHEBI:36745 cedrane sesquiterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36745 CHEBI:36753 eremophilane sesquiterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36753 CHEBI:36754 vetispirane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36754 CHEBI:36751 pyrrole-2-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36751 CHEBI:36757 farnesane sesquiterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36757 CHEBI:36758 apo carotenoid sesquiterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36758 CHEBI:36756 farnesane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36756 CHEBI:22119 UDP-N-acetylmannosaminouronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22119 CHEBI:36750 (R)-1-pyrroline-5-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36750 GO:1901509 regulation of endothelial tube morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901509 Any process that modulates the frequency, rate or extent of endothelial tube morphogenesis. GO:1901507 negative regulation of acylglycerol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901507 down-regulation of acylglycerol transport|inhibition of glyceride transport|downregulation of acylglycerol transport|down regulation of acylglycerol transport|inhibition of acylglycerol transport|down regulation of glyceride transport|downregulation of glyceride transport|negative regulation of glyceride transport|down-regulation of glyceride transport Any process that stops, prevents or reduces the frequency, rate or extent of acylglycerol transport. GO:1901508 positive regulation of acylglycerol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901508 up-regulation of glyceride transport|up regulation of acylglycerol transport|upregulation of glyceride transport|upregulation of acylglycerol transport|up regulation of glyceride transport|activation of glyceride transport|positive regulation of glyceride transport|up-regulation of acylglycerol transport|activation of acylglycerol transport Any process that activates or increases the frequency, rate or extent of acylglycerol transport. GO:1901505 carbohydrate derivative transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901505 carbohydrate derivative transporter activity Enables the transfer of carbohydrate derivative from one side of a membrane to the other. GO:1901506 regulation of acylglycerol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901506 regulation of glyceride transport Any process that modulates the frequency, rate or extent of acylglycerol transport. GO:1901503 ether biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901503 ether biosynthesis|ether anabolism|ether synthesis|ether formation The chemical reactions and pathways resulting in the formation of ether. GO:1901504 triazole transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901504 The directed movement of a triazole into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:1901501 response to xylene biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901501 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xylene stimulus. CHEBI:36728 20-hydroxypregn-4-en-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36728 CHEBI:36729 (20R)-20-hydroxypregn-4-en-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36729 GO:1901502 ether catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901502 ether degradation|ether catabolism|ether breakdown The chemical reactions and pathways resulting in the breakdown of ether. CHEBI:36726 17,20-dihydroxypregn-4-en-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36726 GO:1901500 response to p-xylene biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901500 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a p-xylene stimulus. CHEBI:36727 1-alkyl-2,3-diacylglycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36727 CHEBI:36721 pentachlorobiphenyl biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36721 GO:0060410 negative regulation of acetylcholine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060410 Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues. GO:0060411 cardiac septum morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060411 heart septum morphogenesis The process in which the anatomical structure of a cardiac septum is generated and organized. A cardiac septum is a partition that separates parts of the heart. GO:0060412 ventricular septum morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060412 interventricular septum morphogenesis The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another. GO:0060413 atrial septum morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060413 interatrial septum morphogenesis The developmental process in which atrial septum is generated and organized. The atrial septum separates the upper chambers (the atria) of the heart from one another. GO:0060414 aorta smooth muscle tissue morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060414 The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body. GO:0060415 muscle tissue morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060415 The process in which the anatomical structures of muscle tissue are generated and organized. Muscle tissue consists of a set of cells that are part of an organ and carry out a contractive function. GO:0060416 response to growth hormone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060416 response to growth hormone stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth. GO:0060417 yolk biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0060417 The cytoplasmic part that serves as a nutrient reserve or energy source for the developing embryo. GO:0060418 yolk plasma biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0060418 Discrete structures that partition the water-soluble portion of the yolk of oocytes and ova, which may or may not be membrane enclosed. GO:0060419 heart growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060419 The increase in size or mass of the heart. GO:1901518 aspyridone A biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901518 aspyridone A formation|aspyridone A biosynthesis|aspyridone A anabolism|aspyridone A synthesis The chemical reactions and pathways resulting in the formation of aspyridone A. GO:1901519 aspyridone B metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901519 aspyridone B metabolism The chemical reactions and pathways involving aspyridone B. GO:1901516 aspyridone A metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901516 aspyridone A metabolism The chemical reactions and pathways involving aspyridone A. GO:1901517 aspyridone A catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901517 aspyridone A degradation|aspyridone A catabolism|aspyridone A breakdown The chemical reactions and pathways resulting in the breakdown of aspyridone A. GO:1901514 ATPase-coupled lipo-chitin oligosaccharide transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901514 lipo-chitin oligosaccharide transmembrane-transporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + lipo-chitin oligosaccharide(in) = ADP + phosphate + lipo-chitin oligosaccharide(out). GO:1901515 poly-beta-1,6-N-acetyl-D-glucosamine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901515 Enables the transfer of poly-beta-1,6-N-acetyl-D-glucosamine from one side of a membrane to the other. GO:1901512 (-)-microperfuranone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901512 (-)-microperfuranone biosynthesis|(-)-microperfuranone anabolism|(-)-microperfuranone synthesis|(-)-microperfuranone formation The chemical reactions and pathways resulting in the formation of (-)-microperfuranone. CHEBI:36739 fenchane monoterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36739 GO:1901513 lipo-chitin oligosaccharide transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901513 Enables the transfer of lipo-chitin oligosaccharide from one side of a membrane to the other. GO:1901510 (-)-microperfuranone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901510 (-)-microperfuranone metabolism The chemical reactions and pathways involving (-)-microperfuranone. CHEBI:36737 bilene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36737 GO:1901511 (-)-microperfuranone catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901511 (-)-microperfuranone degradation|(-)-microperfuranone breakdown|(-)-microperfuranone catabolism The chemical reactions and pathways resulting in the breakdown of (-)-microperfuranone. CHEBI:36738 biladiene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36738 CHEBI:36732 bilene-b biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36732 GO:0060400 negative regulation of growth hormone receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060400 negative regulation of growth hormone receptor signalling pathway Any process that decreases the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand. CHEBI:36730 hydroxypregnenolone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36730 CHEBI:36735 biladienes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36735 GO:0060401 cytosolic calcium ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060401 The directed movement of calcium ions (Ca2+) into, out of or within the cytosol. GO:0060402 calcium ion transport into cytosol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060402 The directed movement of calcium ions (Ca2+) into the cytosol. CHEBI:36736 bilenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36736 CHEBI:36733 biladiene-ab biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36733 GO:0060403 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0060403 GO:0060404 axonemal microtubule depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060404 The removal of tubulin heterodimers from one or both ends of an axonemal microtubule. An axonemal microtubule is a microtubule in the axoneme of a cilium or flagellum; an axoneme contains nine modified doublet microtubules surrounding a pair of single microtubules. GO:0060405 regulation of penile erection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060405 Any process that modulates the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow. GO:0060406 positive regulation of penile erection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060406 Any process that increases the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow. GO:0060407 negative regulation of penile erection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060407 Any process that stops, prevents, or reduces the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow. GO:0060408 regulation of acetylcholine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060408 Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues. GO:0060409 positive regulation of acetylcholine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060409 Any process that increases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues. GO:1901529 positive regulation of anion channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901529 activation of anion channel activity|up regulation of anion channel activity|upregulation of anion channel activity|up-regulation of anion channel activity Any process that activates or increases the frequency, rate or extent of anion channel activity. GO:1901527 abscisic acid-activated signaling pathway involved in stomatal movement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901527 abscisic acid mediated signalling involved in stomatal movement|abscisic acid mediated signaling pathway involved in stomatal movement Any abscisic acid mediated signaling pathway that is involved in stomatal movement. GO:1901528 hydrogen peroxide mediated signaling pathway involved in stomatal movement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901528 hydrogen peroxide mediated signalling pathway involved in stomatal movement|H2O2 mediated signaling pathway involved in stomatal movement Any hydrogen peroxide mediated signaling pathway that is involved in stomatal movement. GO:1901525 negative regulation of mitophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901525 downregulation of macromitophagy|down regulation of macromitophagy|inhibition of macromitophagy|negative regulation of macromitophagy|down-regulation of macromitophagy Any process that stops, prevents or reduces the frequency, rate or extent of mitophagy. GO:1901526 positive regulation of mitophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901526 up regulation of macromitophagy|upregulation of macromitophagy|positive regulation of macromitophagy|up-regulation of macromitophagy|activation of macromitophagy Any process that activates or increases the frequency, rate or extent of mitophagy. GO:1901523 icosanoid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901523 icosanoid catabolism|icosanoid degradation|icosanoid breakdown The chemical reactions and pathways resulting in the breakdown of icosanoid. CHEBI:224037 3-sulfinato-L-alaninate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_224037 GO:1901524 regulation of mitophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901524 regulation of macromitophagy Any process that modulates the frequency, rate or extent of macromitophagy. CHEBI:36707 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36707 GO:1901521 aspyridone B biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901521 aspyridone B anabolism|aspyridone B synthesis|aspyridone B formation|aspyridone B biosynthesis The chemical reactions and pathways resulting in the formation of aspyridone B. GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901522 positive regulation of global transcription from Pol II promoter involved in cellular response to chemical stimulus|activation of global transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|up regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|up-regulation of global transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|upregulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|upregulation of global transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|positive regulation of transcription from Pol II promoter involved in cellular response to chemical stimulus|activation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|up-regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|stimulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|stimulation of global transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|up regulation of global transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus Any positive regulation of transcription from RNA polymerase II promoter that is involved in cellular response to chemical stimulus. GO:1901520 aspyridone B catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901520 aspyridone B degradation|aspyridone B catabolism|aspyridone B breakdown The chemical reactions and pathways resulting in the breakdown of aspyridone B. CHEBI:36709 aminoquinoline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36709 GO:0060430 lung saccule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060430 lung saccular development The biological process whose specific outcome is the progression of a lung saccule from an initial condition to its mature state. The lung saccule is the primitive gas exchange portion of the lung composed of type I and type II cells. GO:0060431 primary lung bud formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060431 lung formation The morphogenetic process in which the foregut region specified to become the lung forms the initial left and right buds. GO:0060432 lung pattern specification process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060432 Any developmental process that results in the creation of defined areas or spaces within the lung, to which cells respond and eventually are instructed to differentiate. GO:0060433 bronchus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060433 The biological process whose specific outcome is the progression of a bronchus from an initial condition to its mature state. This process begins with the formation of the bronchus and ends with the mature structure. The bronchus is the portion of the airway that connects to the lungs. CHEBI:36702 2-acyl-1-alkyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36702 GO:0060434 bronchus morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060434 The process in which the bronchus is generated and organized. The bronchus is the portion of the airway that connects to the lungs. GO:0060435 bronchiole development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060435 The biological process whose specific outcome is the progression of a bronchiole from an initial condition to its mature state. This process begins with the formation of the bronchiole and ends with the mature structure. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi. CHEBI:36703 tetrachloro-1,4-benzoquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36703 CHEBI:36700 phosphocholines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36700 GO:0060436 bronchiole morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060436 The process in which a bronchiole is generated and organized. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi. GO:0060437 lung growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060437 The increase in size or mass of a lung. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax. GO:0060438 trachea development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060438 The process whose specific outcome is the progression of a trachea over time, from its formation to the mature structure. The trachea is the portion of the airway that attaches to the bronchi as it branches. GO:0060439 trachea morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060439 The process in which a trachea is generated and organized. The trachea is the portion of the airway that attaches to the bronchi as it branches. GO:1901538 changes to DNA methylation involved in embryo development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901538 DNA methylation or demethylation involved in embryogenesis|changes in DNA methylation involved in embryo development|DNA methylation or demethylation involved in embryonal development|changes in DNA methylation involved in embryonal development|changes in DNA methylation involved in embryogenesis The addition or removal of methyl groups to DNA that contributes to the epigenetic regulation of embryonic gene expression. GO:1901539 ent-pimara-8(14),15-diene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901539 ent-pimara-8(14),15-diene metabolism The chemical reactions and pathways involving ent-pimara-8(14),15-diene. GO:1901536 negative regulation of DNA demethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901536 down regulation of DNA demethylation|downregulation of DNA demethylation|down-regulation of DNA demethylation|inhibition of DNA demethylation Any process that stops, prevents or reduces the frequency, rate or extent of DNA demethylation. GO:1901537 positive regulation of DNA demethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901537 upregulation of DNA demethylation|up regulation of DNA demethylation|activation of DNA demethylation|up-regulation of DNA demethylation Any process that activates or increases the frequency, rate or extent of DNA demethylation. GO:1901534 positive regulation of hematopoietic progenitor cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901534 up regulation of hematopoietic progenitor cell differentiation|up-regulation of haemopoietic progenitor cell differentiation|positive regulation of hemopoietic progenitor cell differentiation|upregulation of haematopoietic progenitor cell differentiation|upregulation of hemopoietic progenitor cell differentiation|activation of haemopoietic progenitor cell differentiation|activation of hematopoietic progenitor cell differentiation|positive regulation of haemopoietic progenitor cell differentiation|up-regulation of haematopoietic progenitor cell differentiation|up-regulation of hematopoietic progenitor cell differentiation|up regulation of haemopoietic progenitor cell differentiation|up regulation of hemopoietic progenitor cell differentiation|activation of hemopoietic progenitor cell differentiation|activation of haematopoietic progenitor cell differentiation|upregulation of hematopoietic progenitor cell differentiation|upregulation of haemopoietic progenitor cell differentiation|positive regulation of haematopoietic progenitor cell differentiation|up regulation of haematopoietic progenitor cell differentiation|up-regulation of hemopoietic progenitor cell differentiation Any process that activates or increases the frequency, rate or extent of hematopoietic progenitor cell differentiation. CHEBI:36717 monochlorobiphenyl biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36717 GO:1901535 regulation of DNA demethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901535 Any process that modulates the frequency, rate or extent of DNA demethylation. GO:1901532 regulation of hematopoietic progenitor cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901532 regulation of haemopoietic progenitor cell differentiation|regulation of hemopoietic progenitor cell differentiation|regulation of haematopoietic progenitor cell differentiation Any process that modulates the frequency, rate or extent of hematopoietic progenitor cell differentiation. GO:1901533 negative regulation of hematopoietic progenitor cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901533 down regulation of haematopoietic progenitor cell differentiation|negative regulation of hemopoietic progenitor cell differentiation|down-regulation of hematopoietic progenitor cell differentiation|down regulation of hemopoietic progenitor cell differentiation|negative regulation of haemopoietic progenitor cell differentiation|down-regulation of haemopoietic progenitor cell differentiation|inhibition of haematopoietic progenitor cell differentiation|downregulation of hemopoietic progenitor cell differentiation|downregulation of haemopoietic progenitor cell differentiation|inhibition of hematopoietic progenitor cell differentiation|down-regulation of haematopoietic progenitor cell differentiation|down regulation of haemopoietic progenitor cell differentiation|negative regulation of haematopoietic progenitor cell differentiation|down-regulation of hemopoietic progenitor cell differentiation|down regulation of hematopoietic progenitor cell differentiation|inhibition of hemopoietic progenitor cell differentiation|inhibition of haemopoietic progenitor cell differentiation|downregulation of hematopoietic progenitor cell differentiation|downregulation of haematopoietic progenitor cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic progenitor cell differentiation. GO:1901530 response to hypochlorite biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901530 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hypochlorite stimulus. GO:1901531 hypochlorite binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901531 Interacting selectively and non-covalently with hypochlorite. GO:0060420 regulation of heart growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060420 Any process that modulates the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart. GO:0060421 positive regulation of heart growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060421 Any process that increases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart. GO:0060422 peptidyl-dipeptidase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0060422 Wikipedia:ACE_inhibitor Stops, prevents or reduces the activity of a peptidyl-dipeptidase. Peptidyl-dipeptidase activity catalyzes the release of C-terminal dipeptides from a polypeptide chain. CHEBI:36713 5alpha-androstane-3alpha,17beta-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36713 GO:0060423 foregut regionalization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060423 The pattern specification process that results in the spatial subdivision of an axis or axes along the foregut to define an area or volume in which specific patterns of cell differentiation will take place. GO:0060424 lung field specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060424 lung specification The process that results in the delineation of a specific region of the foregut into the area in which the lung will develop. GO:0060425 lung morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060425 The process in which the anatomical structures of the lung are generated and organized. CHEBI:36711 phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36711 GO:0060426 lung vasculature development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060426 pulmonary vasculature development The biological process whose specific outcome is the progression of a lung vasculature from an initial condition to its mature state. This process begins with the formation of the lung vasculature and ends with the mature structure. The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs. CHEBI:36712 1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36712 GO:0060427 lung connective tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060427 pulmonary connective tissue development The biological process whose specific outcome is the progression of lung connective tissue from an initial condition to its mature state. This process begins with the formation of lung connective tissue and ends with the mature structure. The lung connective tissue is a material made up of fibers forming a framework and support structure for the lungs. GO:0060428 lung epithelium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060428 pulmonary epithelium development The biological process whose specific outcome is the progression of the lung epithelium from an initial condition to its mature state. This process begins with the formation of lung epithelium and ends with the mature structure. The lung epithelium is the specialized epithelium that lines the inside of the lung. GO:0060429 epithelium development biolink:BiologicalProcess go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0060429 The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. OIO:hasBroadSynonym has_broad_synonym biolink:OntologyClass go-plus http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym NCBITaxon:33154 Opisthokonta organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_33154 opisthokonts|Fungi/Metazoa group GO:1901549 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1901549 GO:1901547 negative regulation of synaptic vesicle lumen acidification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901547 down regulation of synaptic vesicle lumen acidification|inhibition of synaptic vesicle lumen acidification|inhibition of synaptic vesicle lumen pH reduction|negative regulation of proton loading|down regulation of synaptic vesicle lumen pH reduction|downregulation of synaptic vesicle lumen pH reduction|down-regulation of synaptic vesicle lumen acidification|down-regulation of synaptic vesicle lumen pH reduction|negative regulation of synaptic vesicle lumen pH reduction|downregulation of synaptic vesicle lumen acidification Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle lumen acidification. GO:1901548 positive regulation of synaptic vesicle lumen acidification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901548 up-regulation of synaptic vesicle lumen pH reduction|upregulation of synaptic vesicle lumen acidification|upregulation of synaptic vesicle lumen pH reduction|activation of synaptic vesicle lumen acidification|up-regulation of synaptic vesicle lumen acidification|positive regulation of proton loading|up regulation of synaptic vesicle lumen pH reduction|activation of synaptic vesicle lumen pH reduction|positive regulation of synaptic vesicle lumen pH reduction|up regulation of synaptic vesicle lumen acidification Any process that activates or increases the frequency, rate or extent of synaptic vesicle lumen acidification. GO:1901545 response to raffinose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901545 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a raffinose stimulus. GO:1901546 regulation of synaptic vesicle lumen acidification biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_1901546 regulation of synaptic vesicle lumen pH reduction|regulation of synaptic vesicle lumen proton loading Any process that modulates the frequency, rate or extent of synaptic vesicle lumen acidification. GO:1901543 negative regulation of ent-pimara-8(14),15-diene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901543 downregulation of ent-pimara-8(14),15-diene biosynthesis|downregulation of ent-pimara-8(14),15-diene biosynthetic process|down-regulation of ent-pimara-8(14),15-diene anabolism|negative regulation of ent-pimara-8(14),15-diene anabolism|down regulation of ent-pimara-8(14),15-diene biosynthesis|down regulation of ent-pimara-8(14),15-diene biosynthetic process|down-regulation of ent-pimara-8(14),15-diene synthesis|negative regulation of ent-pimara-8(14),15-diene synthesis|inhibition of ent-pimara-8(14),15-diene biosynthesis|inhibition of ent-pimara-8(14),15-diene biosynthetic process|down-regulation of ent-pimara-8(14),15-diene formation|inhibition of ent-pimara-8(14),15-diene anabolism|negative regulation of ent-pimara-8(14),15-diene formation|inhibition of ent-pimara-8(14),15-diene synthesis|inhibition of ent-pimara-8(14),15-diene formation|down regulation of ent-pimara-8(14),15-diene anabolism|down-regulation of ent-pimara-8(14),15-diene biosynthetic process|negative regulation of ent-pimara-8(14),15-diene biosynthesis|down-regulation of ent-pimara-8(14),15-diene biosynthesis|downregulation of ent-pimara-8(14),15-diene anabolism|down regulation of ent-pimara-8(14),15-diene synthesis|down regulation of ent-pimara-8(14),15-diene formation|downregulation of ent-pimara-8(14),15-diene synthesis|downregulation of ent-pimara-8(14),15-diene formation Any process that stops, prevents or reduces the frequency, rate or extent of ent-pimara-8(14),15-diene biosynthetic process. GO:1901544 positive regulation of ent-pimara-8(14),15-diene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901544 up regulation of ent-pimara-8(14),15-diene synthesis|activation of ent-pimara-8(14),15-diene synthesis|positive regulation of ent-pimara-8(14),15-diene synthesis|up regulation of ent-pimara-8(14),15-diene formation|activation of ent-pimara-8(14),15-diene formation|positive regulation of ent-pimara-8(14),15-diene formation|upregulation of ent-pimara-8(14),15-diene biosynthesis|upregulation of ent-pimara-8(14),15-diene biosynthetic process|up-regulation of ent-pimara-8(14),15-diene anabolism|up-regulation of ent-pimara-8(14),15-diene synthesis|up-regulation of ent-pimara-8(14),15-diene formation|up-regulation of ent-pimara-8(14),15-diene biosynthesis|activation of ent-pimara-8(14),15-diene biosynthesis|activation of ent-pimara-8(14),15-diene biosynthetic process|up-regulation of ent-pimara-8(14),15-diene biosynthetic process|upregulation of ent-pimara-8(14),15-diene anabolism|upregulation of ent-pimara-8(14),15-diene synthesis|upregulation of ent-pimara-8(14),15-diene formation|up regulation of ent-pimara-8(14),15-diene anabolism|positive regulation of ent-pimara-8(14),15-diene biosynthesis|activation of ent-pimara-8(14),15-diene anabolism|positive regulation of ent-pimara-8(14),15-diene anabolism|up regulation of ent-pimara-8(14),15-diene biosynthesis|up regulation of ent-pimara-8(14),15-diene biosynthetic process Any process that activates or increases the frequency, rate or extent of ent-pimara-8(14),15-diene biosynthetic process. GO:1901541 ent-pimara-8(14),15-diene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901541 ent-pimara-8(14),15-diene anabolism|ent-pimara-8(14),15-diene synthesis|ent-pimara-8(14),15-diene formation|ent-pimara-8(14),15-diene biosynthesis The chemical reactions and pathways resulting in the formation of ent-pimara-8(14),15-diene. GO:1901542 regulation of ent-pimara-8(14),15-diene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901542 regulation of ent-pimara-8(14),15-diene biosynthesis|regulation of ent-pimara-8(14),15-diene anabolism|regulation of ent-pimara-8(14),15-diene synthesis|regulation of ent-pimara-8(14),15-diene formation Any process that modulates the frequency, rate or extent of ent-pimara-8(14),15-diene biosynthetic process. GO:0060450 positive regulation of hindgut contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060450 Any process that increases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine. GO:0060451 negative regulation of hindgut contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060451 Any process that decreases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine. GO:1901540 ent-pimara-8(14),15-diene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901540 ent-pimara-8(14),15-diene catabolism|ent-pimara-8(14),15-diene degradation|ent-pimara-8(14),15-diene breakdown The chemical reactions and pathways resulting in the breakdown of ent-pimara-8(14),15-diene. GO:0060452 positive regulation of cardiac muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060452 Any process that increases the frequency, rate or extent of cardiac muscle contraction. GO:0060453 regulation of gastric acid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060453 Any process that modulates the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion. GO:0060454 positive regulation of gastric acid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060454 Any process that increases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion. CHEBI:12755 indol-3-ylacetyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_12755 GO:0060455 negative regulation of gastric acid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060455 Any process that decreases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion. GO:0060456 positive regulation of digestive system process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060456 Any process that increases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. GO:0060457 negative regulation of digestive system process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060457 Any process that decreases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. GO:0060458 right lung development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060458 right pulmonary development The biological process whose specific outcome is the progression of a right lung from an initial condition to its mature state. This process begins with the formation of the right lung and ends with the mature structure. The right lung is the lung which is on the right side of the anterior posterior axis looking from a dorsal to ventral aspect. GO:0060459 left lung development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060459 left pulmonary development The biological process whose specific outcome is the progression of a left lung from an initial condition to its mature state. This process begins with the formation of the left lung and ends with the mature structure. The left lung is the lung which is on the left side of the anterior posterior axis looking from a dorsal to ventral aspect. OBO:GOCHE_27314 substance with water-soluble vitamin role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_27314 GO:1901558 response to metformin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901558 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metformin stimulus. GO:1901559 response to ribavirin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901559 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ribavirin stimulus. GO:1901556 response to candesartan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901556 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a candesartan stimulus. GO:1901557 response to fenofibrate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901557 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fenofibrate stimulus. GO:1901554 response to paracetamol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901554 response to acetaminophen Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paracetamol stimulus. GO:1901555 response to paclitaxel biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901555 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paclitaxel stimulus. GO:1901552 positive regulation of endothelial cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901552 activation of endothelial cell development|up regulation of endothelial cell development|upregulation of endothelial cell development|up-regulation of endothelial cell development Any process that activates or increases the frequency, rate or extent of endothelial cell development. GO:1901553 malonic acid transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901553 malonic acid membrane transport The directed movement of malonic acid across a membrane. GO:1901550 regulation of endothelial cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901550 Any process that modulates the frequency, rate or extent of endothelial cell development. GO:1901551 negative regulation of endothelial cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901551 down-regulation of endothelial cell development|downregulation of endothelial cell development|down regulation of endothelial cell development|inhibition of endothelial cell development Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell development. GO:0060440 trachea formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060440 The process pertaining to the initial formation of a trachea from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the trachea is recognizable. The trachea is the portion of the airway that attaches to the bronchi as it branches. GO:0060441 epithelial tube branching involved in lung morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060441 lung branching morphogenesis The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. GO:0060442 branching involved in prostate gland morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060442 prostate branching|prostate gland branching morphogenesis The process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem. GO:1901560 response to purvalanol A biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901560 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purvalanol A stimulus. GO:0060443 mammary gland morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060443 The process in which anatomical structures of the mammary gland are generated and organized. Morphogenesis refers to the creation of shape. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. GO:0060444 branching involved in mammary gland duct morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060444 mammary gland branching morphogenesis The process in which the branching structure of the mammary gland duct is generated and organized. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. GO:0060445 branching involved in salivary gland morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060445 The process in which the branching structure of the salivary gland is generated and organized. GO:0060446 branching involved in open tracheal system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060446 The process in which the anatomical structures of branches in the open tracheal system are generated and organized. GO:0060447 bud outgrowth involved in lung branching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060447 bud formation involved in lung branching The process in which a region of the lung epithelium initiates an outgrowth. GO:0060448 dichotomous subdivision of terminal units involved in lung branching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060448 bud bifurcation involved in lung branching The process in which a lung bud bifurcates. GO:0060449 bud elongation involved in lung branching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060449 The process in which a bud in the lung grows out from the point where it is formed. OBA:0005425 metanephros morphology biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0005425 morphology of metanephros The morphology of a metanephros. UBERON:0013411 cranial cavity biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013411 cavitas cranii|intracranial space|intracranial cavity Anatomical cavity that is the lumen of the skull and contains the brain. CHEBI:131954 GDP-4-amino-3,4,6-trideoxy-alpha-D-threo-hex-3-enopyranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131954 CHEBI:131955 (5E)-tetradecenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131955 CHEBI:22064 S-palmitoyl amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22064 CHEBI:61672 dihydrocarvones biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61672 CHEBI:131957 (5E)-tetradecenoyl-L-carnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131957 CHEBI:22065 S-palmitoyl-L-cysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22065 CHEBI:131958 (13S,14S)-epoxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131958 CHEBI:85640 cis-3-octenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85640 CHEBI:61670 oroxylin A 7-O-beta-D-glucuronide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61670 PR:000036929 polyubiquitin biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000036929 fam:polyUb A protein that contains multiple tandem copies of the Ubiquitin (Pfam:PF00240) domain over the entire length of the sequence. CHEBI:131959 phosphinomethylisomalic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131959 CHEBI:85641 (9E)-12-hydroxyoctadec-9-enoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85641 CHEBI:22063 sulfoxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22063 CHEBI:85643 3'-terminal pUpU(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85643 CHEBI:85644 UMP 2',3'-cyclic phosphate(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85644 CHEBI:61677 (+)-alpha-santalene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61677 CHEBI:61674 oroxylin A 7-O-beta-D-glucuronate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61674 CHEBI:131950 2-aminobenzoylacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131950 CHEBI:116314 oleamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_116314 CHEBI:61678 (+)-endo-beta-bergamotene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61678 CHEBI:131951 4-methylpentanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131951 CHEBI:61679 (-)-endo-alpha-bergamotene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61679 CHEBI:131952 2-aminobenzoylacetyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131952 CHEBI:46024 trichostatin A biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46024 CHEBI:71007 3-dehydrohexadecasphinganine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71007 CHEBI:71008 3-dehydrotetradecasphinganine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71008 CHEBI:71009 hexadecasphinganine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71009 CHEBI:131964 (14S,15R)-EET(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131964 CHEBI:131965 (14R,15S)-EET(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131965 CHEBI:61680 (1S,4aS)-1,4a-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61680 CHEBI:131966 (2Z,4S,5R)-2-amino-4,5,6-trihydroxyhex-2-enoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131966 CHEBI:131967 (4S,5R)-4,5,6-trihydroxy-2-iminohexanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131967 CHEBI:61683 ubiquinone-8 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61683 CHEBI:131969 (11S,12R)-EET(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131969 CHEBI:61684 menaquinol-8 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61684 CHEBI:85630 (Kdo)2-lipid A 1-diphosphate (E. coli) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85630 CHEBI:61682 ubiquinol-8 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61682 CHEBI:61687 cis-muurola-3,5-diene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61687 CHEBI:61688 cis-muurola-4(14),5-diene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61688 CHEBI:61685 (+)-cubenene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61685 CHEBI:85634 (3R)-3-hydroxy fatty acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85634 CHEBI:85635 (R)-3-hydroxytetradecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85635 CHEBI:61686 (+)-epicubenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61686 CHEBI:85636 (2R)-2-hydroxytetradecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85636 CHEBI:85637 (2S)-2-hydroxytetradecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85637 CHEBI:131962 (3E)-octenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131962 CHEBI:85638 haloacetate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85638 CHEBI:61689 amino cyclitol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61689 CHEBI:85639 (9Z)-12-hydroxyoctadec-9-enoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85639 CHEBI:131963 2-(phosphinomethylidene)succinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131963 CHEBI:22046 S-geranylgeranyl-L-cysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22046 CHEBI:71017 1-hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71017 CHEBI:155902 4-hydroxy-5-(4-hydroxybenzylidene)-3-(4-hydroxyphenyl)furan-2(5H)-one biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_155902 CHEBI:155900 4-quinolone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_155900 CHEBI:61690 (+)-alpha-barbatene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61690 CHEBI:131932 glycosmisate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131932 CHEBI:131933 (-)-DCA-CL(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131933 CHEBI:85660 N-stearoyl-1-oleoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85660 CHEBI:131934 (-)-DCA-CC(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131934 CHEBI:61694 L-cysteinylglycine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61694 CHEBI:131935 (+)-DCA-CC(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131935 CHEBI:85661 9,10-epoxyoctadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85661 CHEBI:61695 L-prolylglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61695 CHEBI:131936 (+)-DCA-CL(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131936 CHEBI:22043 S-farnesyl-L-cysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22043 PR:000036907 amino acid chain component biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000036907 amino-acid residue A fiat object part that is either a modified amino-acid residue or an unmodified amino-acid residue. CHEBI:131937 ent-glycosmisate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131937 CHEBI:131938 validoxylamine A 7'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131938 CHEBI:85664 N,1-dioleoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85664 CHEBI:61693 carboxyalkyl phosphate oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61693 CHEBI:36687 acyl chloride biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36687 CHEBI:61698 L-ascorbate 6-phosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61698 CHEBI:36688 heterotricyclic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36688 CHEBI:61699 (-)-alpha-gurjunene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61699 CHEBI:85666 N-arachidonoyl-1-oleoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85666 CHEBI:36685 chlorocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36685 CHEBI:61696 L-prolinylglycine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61696 CHEBI:85667 N-icosanoyl-1-oleoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85667 CHEBI:36686 chloroarene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36686 CHEBI:85668 N-octadecanoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85668 CHEBI:61697 fatty acid derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61697 CHEBI:85669 N-icosanoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85669 CHEBI:131930 validamine 7-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131930 CHEBI:36680 heteranthrene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36680 CHEBI:36683 organochlorine compound biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36683 CHEBI:71010 tetradecasphinganine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71010 CHEBI:71011 hexadecasphing-4-enine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71011 CHEBI:36682 polychlorinated dibenzodioxine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36682 CHEBI:131943 (5E)-tetradecenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131943 CHEBI:131944 (2E,5E)-tetradecadienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131944 CHEBI:131946 valienone 7-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131946 CHEBI:85650 (11E,13Z)-octadecadienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85650 CHEBI:85651 (5Z,11E)-octadecadienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85651 CHEBI:131948 nocardicin C dizwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131948 CHEBI:85652 (6Z,11E)-octadecadienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85652 CHEBI:131949 validone 7-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131949 CHEBI:85654 N-palmitoyl-1-oleoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85654 CHEBI:36699 corticosteroid hormone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36699 CHEBI:85655 (3E)-nonenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85655 CHEBI:85656 N-acyllysophosphatidylethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85656 CHEBI:36697 1,2,4,5-tetrachlorobenzene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36697 CHEBI:85657 N-hexadecanoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85657 CHEBI:85658 N-acyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85658 CHEBI:85659 (3E)-phycoerythrobilin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85659 CHEBI:131941 validoxylamine A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131941 CHEBI:71021 15-methylhexadecasphing-4-enine-1-phosphocholine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71021 CHEBI:71036 15-methylhexadecasphing-4-enine 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71036 CHEBI:131919 nocardicin G zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131919 CHEBI:71038 3-hydroxyadipyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71038 UBERON:0013455 spheno-petrosal fissure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013455 sphenopetrosal fissure|fissura sphenopetrosa The sphenopetrosal fissure (or sphenopetrosal suture) is the cranial suture between the sphenoid bone and the petrous portion of the temporal bone. It is in the middle cranial fossa. CHEBI:85680 1,2-dioleoyl-sn-glycero-3-phospho-N,N-dimethylethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85680 CHEBI:131912 O-[S-(3-hydroxy-4-methylanthraniloyl)pantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131912 CHEBI:131913 O-[S-(3,5-dihydroxy-4-methylanthraniloyl)pantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131913 CHEBI:22020 S-(ADP-ribosyl)-L-cysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22020 CHEBI:131914 violacein biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131914 CHEBI:131915 deoxyviolacein biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131915 CHEBI:131916 proviolacein biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131916 CHEBI:85687 diacylglycerol 32:1 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85687 CHEBI:85688 diacylglycerol 32:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85688 CHEBI:71030 15-methylhexadecasphinganine 1-phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71030 CHEBI:71034 13-methyltetradecanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71034 CHEBI:36660 elemental tellurium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36660 CHEBI:131928 N-hydroxy-2-methylpropanamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131928 CHEBI:71046 tetradecasphinganine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71046 CHEBI:131929 (E)-3-(indol-3-yl)acrylate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131929 CHEBI:71048 (S)-dihydrocamalexate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71048 CHEBI:131920 isonocardicin C dizwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131920 CHEBI:131921 ethylenediaminetriacetate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131921 CHEBI:131922 ethylenediaminediacetate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131922 CHEBI:85670 N-oleoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85670 CHEBI:85671 N-arachidonoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85671 CHEBI:85672 1-(9Z-octadecenyl)-2-arachidonoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85672 CHEBI:85674 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85674 CHEBI:85675 3-phenylpropanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85675 CHEBI:131927 dicarboxylic acids and O-substituted derivatives biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131927 CHEBI:85676 3-phenylpropanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85676 CHEBI:36674 phenazine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36674 CHEBI:85678 (3R)-3-hydroxy fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85678 CHEBI:85679 1,2-dioleoyl-sn-glycero-3-phospho-N-methylethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85679 CHEBI:71041 3-dehydrohexadecasphinganine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71041 CHEBI:71043 3-dehydrotetradecasphinganine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71043 CHEBI:71044 2,3-didehydroadipoyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71044 CHEBI:71045 bisdemethoxycurcumin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71045 CHEBI:71059 15-methylhexadecasphinganine 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71059 CHEBI:36641 3aH-benzimidazole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36641 OBA:VT0100007 growth trait biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_VT0100007 quality of growth The quality of a growth. CHEBI:36642 glycohexaosylceramide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36642 CHEBI:36647 2,3-dihydroxy-p-cumate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36647 GO:0060610 mesenchymal cell differentiation involved in mammary gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060610 mammary gland mesenchymal cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a mammary gland mesenchymal cell. Mammary gland mesenchymal cells form a loosely connected network of cells that surround the mammary ducts. GO:0060611 mammary gland fat development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060611 The progression of the mammary gland fat over time, from its formation to the mature structure. The mammary fat is an adipose structure in the gland that is invaded by the mammary ducts. GO:0060612 adipose tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060612 adipogenesis The process whose specific outcome is the progression of adipose tissue over time, from its formation to the mature structure. Adipose tissue is specialized tissue that is used to store fat. OBA:VT0100003 organism subdivision trait biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_VT0100003 quality of organism subdivision The quality of a organism subdivision. GO:0060613 fat pad development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060613 The progression of a fat pad from its initial formation to its mature structure. A fat pad is an accumulation of adipose tissue. GO:0060614 negative regulation of mammary gland development in males by androgen receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060614 negative regulation of mammary gland development in males by androgen receptor signalling pathway Any process that decreases the rate or extent of mammary gland development in the male by an androgen binding to its receptor, causing a change in state or activity of a cell. GO:0060615 mammary gland bud formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060615 The morphogenetic process in which a bud forms from the mammary placode. A mammary bud is bulb of epithelial cells that is distinct from the surrounding epidermis. CHEBI:71050 hexadecasphinganine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71050 GO:0060616 mammary gland cord formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060616 mammary gland sprout formation The process in which the mammary gland cord forms by elongation of the mammary bud. The cord is formed once the elongating bud breaks through the mesenchyme and reaches the fat pad. CHEBI:71052 hexadecasphing-4-enine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71052 GO:0060617 positive regulation of mammary placode formation by mesenchymal-epithelial signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060617 positive regulation of mammary placode formation by mesenchymal-epithelial signalling Any process that initiates the formation of a mammary placode through a mechanism that mediates the transfer of information from a mesenchymal cell to an epithelial cell resulting in the epithelial cell adopting the identity of a cell of the mammary placode. GO:0060618 nipple development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060618 The progression of the nipple over time, from its formation to the mature structure. The nipple is a part of the mammary gland that protrudes from the surface ectoderm. GO:0060619 cell migration involved in mammary placode formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060619 The orderly movement of epithelial cells within the mammary line that contributes to the formation of the mammary placode. CHEBI:36640 glycoheptaosylceramide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36640 CHEBI:71056 15-methylhexadecasphing-4-enine-1-phosphocholine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71056 CHEBI:131906 4-pyranones biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131906 CHEBI:131907 3-pyrones biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131907 CHEBI:85694 diacylglycerol 34:1 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85694 CHEBI:36654 2,3-dihydroxybenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36654 CHEBI:36655 glyoxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36655 CHEBI:36658 6-methylsalicylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36658 CHEBI:36659 3-(4-hydroxyphenyl)lactate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36659 GO:0060600 dichotomous subdivision of an epithelial terminal unit biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060600 primary branching of an epithelium The process in which an epithelial cord, rod or tube bifurcates at its end. GO:0060601 lateral sprouting from an epithelium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060601 The process in which a branch forms along the side of an epithelium. CHEBI:36656 phenylglyoxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36656 GO:0060602 branch elongation of an epithelium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060602 The growth process in which a branch increases in length from its base to its tip. GO:0060603 mammary gland duct morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060603 The process in which anatomical structures of the mammary ducts are generated and organized. Mammary ducts are epithelial tubes that transport milk. GO:0060604 mammary gland duct cavitation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060604 milk duct cavitation Creation of the central hole of the mammary gland duct by the hollowing out of a solid rod. GO:0060605 tube lumen cavitation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060605 The formation of a lumen by hollowing out a solid rod or cord. GO:0060606 tube closure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060606 Creation of the central hole of a tube in an anatomical structure by sealing the edges of an epithelial fold. CHEBI:71063 N-retinylidenephosphatidylethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71063 GO:0060607 cell-cell adhesion involved in sealing an epithelial fold biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060607 The attachment of one cell to another cell along the edges of two epithelial folds, giving rise to the lumen of an epithelial tube. GO:0060608 cell-cell adhesion involved in neural tube closure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060608 The attachment of one cell to another cell along the edges of two epithelial folds, giving rise to the lumen of the neural tube. GO:0060609 apoptotic process involved in tube lumen cavitation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060609 apoptosis involved in tube lumen cavitation Any apoptotic process that contributes to the hollowing out of an epithelial rod or cord to form the central hole in a tube. GO:0035669 TRAM-dependent toll-like receptor 4 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035669 TRAM-dependent TLR4 signaling pathway|TRAM-dependent toll-like receptor 4 signalling pathway Any series of molecular signals generated as a consequence of binding to a toll-like receptor 4 where the TRAM adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response. GO:0035661 MyD88-dependent toll-like receptor 2 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035661 MyD88-dependent TLR2 signaling pathway|MyD88-dependent toll-like receptor 2 signalling pathway Any series of molecular signals generated as a consequence of binding to a toll-like 2 receptor where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like 2 receptors are pattern recognition receptors that bind microbial pattern motifs to initiate an innate immune response. GO:0035662 Toll-like receptor 4 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035662 TLR4 binding Interacting selectively and non-covalently with a Toll-like 4 protein, a pattern recognition receptor that binds bacterial lipopolysaccharide (LPS) to initiate an innate immune response. GO:0035663 Toll-like receptor 2 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035663 TLR2 binding Interacting selectively and non-covalently with a Toll-like 2 protein, a pattern recognition receptor that binds microbial pattern motifs to initiate an innate immune response. GO:0035664 TIRAP-dependent toll-like receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035664 MAL-dependent toll-like receptor signaling pathway|TIRAP-dependent TLR signaling pathway|MyD88 adapter-like dependent toll-like receptor signaling pathway|TIRAP-dependent toll-like receptor signalling pathway Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the TIRAP/MAL adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response. GO:0035665 TIRAP-dependent toll-like receptor 4 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035665 MyD88 adapter-like dependent toll-like receptor 4 signaling pathway|TIRAP-dependent TLR4 signaling pathway|TIRAP-dependent toll-like receptor 4 signalling pathway|MAL-dependent toll-like receptor 4 signaling pathway Any series of molecular signals generated as a consequence of binding to a toll-like receptor 4 where the TIRAP/MAL adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response. GO:0035666 TRIF-dependent toll-like receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035666 TRIF-dependent TLR signaling pathway|TRIF-dependent toll-like receptor signalling pathway|Toll/IL-1 receptor (TIR) domain-containing adaptor-dependent TLR signaling pathway Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the TRIF adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response. GO:0035667 TRIF-dependent toll-like receptor 4 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035667 TRIF-dependent toll-like receptor 4 signalling pathway|Toll/IL-1 receptor (TIR) domain-containing adaptor-dependent TLR4 signaling pathway|TRIF-dependent TLR4 signaling pathway Any series of molecular signals generated as a consequence of binding to a toll-like 4 receptor where the TRIF adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response. GO:0035668 TRAM-dependent toll-like receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035668 TRAM-dependent TLR signaling pathway|TRAM-dependent toll-like receptor signalling pathway Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the TRAM adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response. GO:0035660 MyD88-dependent toll-like receptor 4 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035660 MyD88-dependent toll-like receptor 4 signalling pathway|MyD88-dependent TLR4 signaling pathway Any series of molecular signals generated as a consequence of binding to a toll-like 4 receptor, where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like 4 receptors bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response. GO:0035658 Mon1-Ccz1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035658 A protein complex that functions as a guanine nucleotide exchange factor (GEF) and converts Rab-GDP to Rab-GTP. In S. cerevisiae, this complex consists of at least Mon1 and Ccz1, and serves as a GEF for the Rab Ypt7p. GO:0035659 Wnt signaling pathway involved in wound healing, spreading of epidermal cells biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035659 Wnt receptor signalling pathway involved in wound healing, spreading of epidermal cells|Wnt receptor signaling pathway involved in wound healing, spreading of epidermal cells|Wnt-activated signaling pathway involved in wound healing, spreading of epidermal cells The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of a cell in the epidermis that contributes to the migration of an epidermal cell along or through a wound gap to reestablish a continuous epidermis. GO:0035650 AP-1 adaptor complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035650 Interacting selectively and non-covalently with the AP-1 adaptor complex. The AP-1 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of beta1, gamma, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle. In at least humans, the AP-1 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (gamma1 and gamma2, mu1A and mu1B, and sigma1A, sigma1B and sigma1C). GO:0035651 AP-3 adaptor complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035651 Interacting selectively and non-covalently with the AP-3 adaptor complex. The AP-3 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes. In at least humans, the AP-3 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (beta3A and beta3B, mu3A and mu3B, and sigma3A and sigma3B). GO:0035652 clathrin-coated vesicle cargo loading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035652 cargo loading into clathrin-coated vesicle Formation of a macromolecular complex between the cytoplasmic coat proteins on clathrin-coated vesicles and proteins and/or lipoproteins that are going to be transported by a vesicle. GO:0035653 clathrin-coated vesicle cargo loading, AP-1-mediated biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035653 cargo loading into clathrin-coated vesicle, AP-1-mediated Formation of a macromolecular complex between proteins of the AP-1 adaptor complex and proteins and/or lipoproteins that are going to be transported by a clathrin-coated vesicle. The AP-1 adaptor protein complex is a component of the cytoplasmic coat found on clathrin-coated vesicles, and binds to sorting signals of cargo to facilitate their trafficking. GO:0035654 clathrin-coated vesicle cargo loading, AP-3-mediated biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035654 cargo loading into clathrin-coated vesicle, AP-3-mediated Formation of a macromolecular complex between proteins of the AP-3 adaptor complex and proteins and/or lipoproteins that are going to be transported by a clathrin-coated vesicle. In some cases, the AP-3 complex is a heterotetrameric AP-type membrane coat adaptor complex that, in some organisms, links clathrin to the membrane surface of a vesicle. GO:0035655 interleukin-18-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035655 interleukin-18-mediated signalling pathway A series of molecular signals initiated by the binding of interleukin-18 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0035656 obsolete kinesin-associated melanosomal adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035656 kinesin-melanosome adaptor activity OBSOLETE. The activity of linking kinesins, cytoplasmic proteins responsible for moving vesicles and organelles towards the distal end of microtubules, to melanosomes. GO:0035657 eRF1 methyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035657 eRF1 MTase complex A protein complex required for the methylation of a glutamine (Gln) residue in the protein release factor eRF1. In S. cerevisiae, this complex consists of at least Trm112p and Mtq2p. GO:0035647 3-oxo-delta(4,5)-steroid 5-beta-reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035647 3-oxo-delta4,5-steroid 5beta-reductase Catalysis of the reaction: a 3-oxo-delta-4,5-steroid + NADPH + H(+) = a 5-beta-3-oxo-steroid + NADP(+). GO:0035648 circadian mating behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035648 circadian mating rhythm|circadian mating behaviour The fluctuation in mating behavior that occurs over an approximately 24 hour cycle. GO:0035649 Nrd1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035649 A complex that functions in transcription termination of RNA polymerase II transcribed non-coding RNAs. This complex interacts with the carboxy-terminal domain (CTD) of PolII and the terminator sequences in the nascent RNA transcript. In yeast this complex consists of Nrd1p, Nab3p, and Sen1p. CHEBI:61610 beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61610 GO:0035640 exploration behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035640 exploratory behavior|exploratory behaviour|exploration behaviour|open-field behavior The specific behavior of an organism in response to a novel environment or stimulus. GO:0035641 locomotory exploration behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035641 The specific movement from place to place of an organism in response to a novel environment. GO:0035642 histone methyltransferase activity (H3-R17 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035642 histone-arginine N-methyltransferase activity (H3-R17 specific)|histone methylase activity (H3-R17 specific) Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 17) = S-adenosyl-L-homocysteine + (histone H3)-N-methyl-arginine (position 17). This reaction is the addition of a methyl group to arginine at position 17 of histone H3. GO:0035643 L-DOPA receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035643 L-beta-(3,4-Dihydroxyphenyl)alanine receptor activity|L-dopa receptor activity Combining with L-DOPA to initiate a change in cell activity. L-DOPA is the modified amino acid (2S)-2-amino-3-(3,4-dihydroxyphenyl) propanoic acid, and is the precursor to dopamine, norepinephrine (noradrenaline) and epinephrine. GO:0035644 phosphoanandamide dephosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035644 The process of removing one or more phosphate groups from a phosphorylated anandamide. GO:0035645 enteric smooth muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035645 intestinal smooth muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the intestine. GO:0035646 endosome to melanosome transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035646 The directed movement of substances from endosomes to the melanosome, a specialised lysosome-related organelle. GO:0035636 obsolete multi-organism signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035636 signaling between organisms|pheromone signaling|multi-organism signalling|signaling with other organism OBSOLETE. The transfer of information between living organisms. GO:0035637 multicellular organismal signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035637 multicellular organismal signalling The transfer of information occurring at the level of a multicellular organism. GO:0035638 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035638 GO:0035639 purine ribonucleoside triphosphate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035639 purine NTP binding Interacting selectively and non-covalently with a purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar. GO:0035630 bone mineralization involved in bone maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035630 The deposition of hydroxyapatite, involved in the progression of the skeleton from its formation to its mature state. GO:0035631 CD40 receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035631 A protein complex that contains at least CD40 (a cell surface receptor of the tumour necrosis factor receptor (TNFR) superfamily), and other signaling molecules. GO:0035632 mitochondrial prohibitin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035632 mitochondrial inner membrane prohibitin complex A complex composed of two proteins, prohibitin 1 and prohibitin 2 (PHB1/PHB-1 and PHB2/PHB-2) that is highly conserved amongst eukaryotes and associated with the inner mitochondrial membrane. The mitochondrial prohibitin complex is a macromolecular supercomplex composed of repeating heterodimeric subunits of PHB1 and PHB2. The mitochondrial prohibitin complex plays a role in a number of biological processes, including mitochondrial biogenesis and function, development, replicative senescence, and cell death. GO:0035633 maintenance of blood-brain barrier biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035633 maintenance of BBB|maintenance of blood/brain barrier Maintaining the structure and function of the blood-brain barrier, thus ensuring specific regulated transport of substances (e.g. macromolecules, small molecules, ions) into the brain, and out of the brain into the blood circulation. GO:0035634 response to stilbenoid biolink:BiologicalProcess go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0035634 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to a stilbenoid. Stilbenoids are secondary products of heartwood formation in trees that can act as phytoalexins. Stilbenoids are hydroxylated derivatives of stilbene. They belong to the family of phenylpropanoids and share most of their biosynthesis pathway with chalcones. CHEBI:61623 fluoroacetyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61623 GO:0035635 entry of bacterium into host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035635 invasion of bacteria into host cell|bacterial entry into host cell The process in which a bacterium enters a host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0035625 obsolete epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035625 EGFR transactivation by GPCR|EGFR transactivation upon GPCR stimulation|epidermal growth factor receptor transactivation by G-protein coupled receptor signaling pathway|epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signalling pathway OBSOLETE. The process in which an epidermal growth factor-activated receptor is activated via signaling events from a consequence of a G protein-coupled . This is an example of cross-talk between the EGF and GPCR signaling pathways. GO:0035626 juvenile hormone mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035626 juvenile hormone-mediated signaling pathway|juvenile hormone mediated signalling pathway A series of molecular signals initiated by the binding of juvenile hormone to a receptor, and ending with regulation of cell state or activity. GO:0035627 ceramide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035627 The directed movement of ceramides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ceramides are a class of lipid composed of sphingosine linked to a fatty acid. GO:0035628 cystic duct development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035628 The progression of the cystic duct over time, from its formation to the mature structure. The cystic duct runs from the gall bladder to the common bile duct. GO:0035629 N-terminal protein amino acid N-linked glycosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035629 Addition of a carbohydrate or carbohydrate derivative unit via a nitrogen (N) atom of the N-terminal amino acid of a protein. CHEBI:46077 4H-1,2,4-triazole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46077 CHEBI:131990 (2E,5Z)-octadienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131990 GO:0035620 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035620 CHEBI:85602 N-carbamoyl-D-alpha-amino acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85602 CHEBI:61631 N-acetyl-beta-D-glucosaminide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61631 CHEBI:131992 5,6-EET(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131992 GO:0035621 ER to Golgi ceramide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035621 ER to Golgi ceramide translocation|endoplasmic reticulum to Golgi ceramide transport|non-vesicular ceramide trafficking The directed movement of a ceramide from the endoplasmic reticulum (ER) to the Golgi. Ceramides are a class of lipid composed of sphingosine linked to a fatty acid. CHEBI:85603 1-tuberculosinyladenosine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85603 CHEBI:131993 lysophosphatidylethanolamine 22:5 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131993 GO:0035622 intrahepatic bile duct development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035622 IHBD development|intrahepatic biliary duct development The progression of the intrahepatic bile ducts over time, from their formation to the mature structure. Intrahepatic bile ducts (bile ducts within the liver) collect bile from bile canaliculi in the liver, and connect to the extrahepatic bile ducts (bile ducts outside the liver). GO:0035623 renal glucose absorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035623 nephron glucose absorption|glucose reabsorption A renal system process in which glucose is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures. GO:0035624 receptor transactivation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035624 The process in which a receptor is activated by another receptor. Receptor transactivation can occur through different mechanisms and includes cross-talk between signaling pathways where one receptor activates a receptor for a different ligand, and also activation of subunits within a receptor oligomer. CHEBI:46081 fluconazole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46081 GO:0035614 snRNA stem-loop binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035614 snRNA hairpin binding|small nuclear RNA stem-loop binding|snRNA hairpin loop binding Interacting selectively and non-covalently with a stem-loop in a small nuclear RNA (snRNA). An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop. GO:0035615 clathrin adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035615 clathrin-associated adaptor activity Bringing together a cargo protein with clathrin, responsible for the formation of endocytic vesicles. GO:0035616 histone H2B conserved C-terminal lysine deubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035616 budding yeast H2B K123 deubiquitination|mammalian H2B K120 deubiquitination|fission yeast H2B K119 deubiquitination A histone deubiquitination process in which a ubiquitin monomer is removed from a conserved lysine residue in the C-terminus of histone H2B. The conserved lysine residue is K119 in fission yeast, K123 in budding yeast, or K120 in mammals. GO:0035617 stress granule disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035617 SG disassembly The disaggregation of a stress granule into its constituent protein and RNA parts. GO:0035618 root hair biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035618 A long, thin projection from a root epidermal cell that contains F-actin and tubulin, and a cell wall. GO:0035619 root hair tip biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035619 root hair cell tip The tip portion of an outgrowth of a root epidermal cell. GO:0035610 protein side chain deglutamylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035610 shortening of glutamate side chain|removal of posttranslational polyglutamylation The removal of a glutamate residue from the side chain of a protein. Glutamate side chains are added to glutamic acid residues within the primary protein sequence during polyglutamylation. GO:0035611 protein branching point deglutamylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035611 The removal of a branching point glutamate residue. A branching point glutamate connects a glutamate side chain to a gene-encoded glutamate residue. GO:0035612 AP-2 adaptor complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035612 AP-2 clathrin adaptor complex binding Interacting selectively and non-covalently with the AP-2 adaptor complex. The AP-2 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits and links clathrin to the membrane surface of a vesicle. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC). CHEBI:61645 L-seryl-AMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61645 GO:0035613 RNA stem-loop binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035613 RNA hairpin binding|RNA hairpin loop binding Interacting selectively and non-covalently with a stem-loop in an RNA molecule. An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop. CHEBI:61646 fluoroacetyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61646 GO:0035603 fibroblast growth factor receptor signaling pathway involved in hemopoiesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035603 fibroblast growth factor receptor signaling pathway involved in hematopoiesis|FGF receptor signaling pathway involved in hematopoiesis|FGFR signaling pathway involved in hematopoiesis|fibroblast growth factor receptor signalling pathway involved in hemopoiesis The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which contributes to hemopoiesis. CHEBI:131975 (8R,9S)-EET(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131975 GO:0035604 fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035604 fibroblast growth factor receptor signalling pathway involved in positive regulation of cell proliferation in bone marrow|FGFR signaling pathway involved in positive regulation of cell proliferation in bone marrow|FGF receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which activates or increases the frequency, rate or extent of cell proliferation in the bone marrow. CHEBI:46050 docosane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46050 GO:0035605 peptidyl-cysteine S-nitrosylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035605 protein nitrosylase activity|S-nitrosylase activity Catalysis of the transfer of a nitric oxide (NO) group to a sulphur atom within a cysteine residue of a protein. CHEBI:22080 TDP-sugar biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22080 GO:0035606 peptidyl-cysteine S-trans-nitrosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035606 S-transnitrosylation|protein-to-protein transnitrosylation|cysteine-to-cysteine transnitrosylation|cysteine to cysteine nitrosylation Transfer of a nitric oxide (NO) group from one cysteine residue to another. CHEBI:131978 (5aS)-5,5a-dihydrophenazine-1,6-dicarboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131978 GO:0035607 fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035607 FGF receptor signaling pathway involved in orbitofrontal cortex development|fibroblast growth factor receptor signalling pathway involved in orbitofrontal cortex development|FGFR signaling pathway involved in orbitofrontal cortex development The series of molecular signals generated as a consequence of a fibroblast growth factor-type receptor binding to one of its physiological ligands, which contributes to the progression of the orbitofrontal cortex over time from its initial formation until its mature state. CHEBI:46053 2,4,6-trinitrotoluene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46053 CHEBI:131979 5,10-dihydrophenazine-1,6-dicarboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131979 GO:0035608 protein deglutamylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035608 protein amino acid deglutamylation The removal of a glutamate residue from a protein. Glutamate residues in proteins can be gene-encoded, or added as side chains during the protein modification process of polyglutamylation. GO:0035609 C-terminal protein deglutamylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035609 protein primary sequence deglutamylation The removal of a C-terminal, gene-encoded glutamate residue from a protein. CHEBI:85620 Fe4S3 iron-sulfur cluster biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85620 CHEBI:85621 L-3-oxoalanine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85621 CHEBI:61655 steroid saponin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61655 CHEBI:131970 (11R,12S)-EET(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131970 CHEBI:131971 (1R,5aS,6R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131971 GO:0035600 tRNA methylthiolation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035600 The addition of a methylthioether group (-SCH3) to a nucleotide in a tRNA molecule. GO:0035601 protein deacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035601 protein amino acid deacylation The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a protein amino acid. CHEBI:131973 (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1,6-dicarboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131973 GO:0035602 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035602 FGFR signaling pathway involved in negative regulation of apoptosis in bone marrow|fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow|fibroblast growth factor receptor signalling pathway involved in negative regulation of apoptotic process in bone marrow|FGF receptor signaling pathway involved in negative regulation of apoptosis in bone marrow|fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptosis in bone marrow The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which stops, prevents, or reduces the frequency, rate or extent of the occurrence or rate of cell death by apoptotic process in the bone marrow. CHEBI:131974 (8S,9R)-EET(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131974 CHEBI:22099 UDP-D-galactosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22099 CHEBI:131986 1-docosahexaenoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131986 CHEBI:131987 2-docosahexaenoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131987 CHEBI:61661 dTDP-4-acetamido-4,6-dideoxy-D-galactose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61661 CHEBI:61662 2'-deoxyribonucleoside triphosphate oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61662 CHEBI:61660 organic sulfamate oxoanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61660 CHEBI:61665 3-O-(6-O-alpha-D-xylosylphospho-alpha-D-mannopyranosyl)-alpha-D-mannopyranose(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61665 CHEBI:61666 amidobenzoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61666 CHEBI:61663 alpha-D-Manp-(1->3)-alpha-D-Manp biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61663 CHEBI:131980 phenazine-1,6-dicarboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131980 CHEBI:131981 (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131981 CHEBI:61664 3-O-(6-O-alpha-D-xylosylphospho-alpha-D-mannopyranosyl)-alpha-D-mannopyranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61664 CHEBI:61669 2-methylbutanenitrile biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61669 CHEBI:85614 neopikromycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85614 CHEBI:61667 D-hexopyranose 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61667 CHEBI:61668 oroxylin A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61668 GO:1901448 regulation of response to butan-1-ol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901448 Any process that modulates the frequency, rate or extent of response to butan-1-ol. GO:1901449 negative regulation of response to butan-1-ol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901449 down-regulation of response to butan-1-ol|downregulation of response to butan-1-ol|down regulation of response to butan-1-ol|inhibition of response to butan-1-ol Any process that stops, prevents or reduces the frequency, rate or extent of response to butan-1-ol. GO:1901446 negative regulation of response to propan-1-ol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901446 downregulation of response to propan-1-ol|down-regulation of response to propan-1-ol|inhibition of response to propan-1-ol|down regulation of response to propan-1-ol Any process that stops, prevents or reduces the frequency, rate or extent of response to propan-1-ol. GO:1901447 positive regulation of response to propan-1-ol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901447 up regulation of response to propan-1-ol|activation of response to propan-1-ol|up-regulation of response to propan-1-ol|upregulation of response to propan-1-ol Any process that activates or increases the frequency, rate or extent of response to propan-1-ol. GO:1901444 positive regulation of response to furfural biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901444 up-regulation of response to furfural|activation of response to furfural|up regulation of response to furfural|upregulation of response to furfural Any process that activates or increases the frequency, rate or extent of response to furfural. GO:0060590 ATPase regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0060590 Modulates the rate of ATP hydrolysis by an ATPase. GO:1901445 regulation of response to propan-1-ol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901445 Any process that modulates the frequency, rate or extent of response to propan-1-ol. GO:1901442 regulation of response to furfural biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901442 Any process that modulates the frequency, rate or extent of response to furfural. GO:0060591 chondroblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060591 chondrocyte progenitor cell differentiation The process in which a mesenchymal cell, acquires specialized structural and/or functional features of a chondroblast. Differentiation includes the processes involved in commitment of a cell to a chondroblast fate. A chondroblast is a precursor cell to chondrocytes. GO:0060592 mammary gland formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060592 mammary placode formation|mammary line formation|mammary bud formation|mammary sprout formation The process pertaining to the initial formation of the mammary gland from unspecified parts. The process begins with formation of the mammary line and ends when the solid mammary bud invades the primary mammary mesenchyme. GO:1901443 negative regulation of response to furfural biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901443 down-regulation of response to furfural|downregulation of response to furfural|down regulation of response to furfural|inhibition of response to furfural Any process that stops, prevents or reduces the frequency, rate or extent of response to furfural. GO:1901440 poly(hydroxyalkanoate) metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901440 poly(hydroxyalkanoate) metabolism The chemical reactions and pathways involving poly(hydroxyalkanoate). GO:0060593 Wnt signaling pathway involved in mammary gland specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060593 Wnt receptor signalling pathway involved in mammary gland specification|Wnt receptor signaling pathway involved in mammary gland specification|Wnt-activated signaling pathway involved in mammary gland specification The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of a cell in the epidermis resulting in the formation of the mammary line. The mammary line is a ridge of epidermal cells that will form the mammary placodes. GO:0060594 mammary gland specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060594 mammary line specification The regionalization process in which the mammary line is specified. The mammary line is a ridge of epidermal cells that will form the mammary placodes. GO:1901441 poly(hydroxyalkanoate) biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901441 poly(hydroxyalkanoate) anabolism|poly(hydroxyalkanoate) synthesis|poly(hydroxyalkanoate) formation|poly(hydroxyalkanoate) biosynthesis The chemical reactions and pathways resulting in the formation of poly(hydroxyalkanoate). GO:0060595 fibroblast growth factor receptor signaling pathway involved in mammary gland specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060595 fibroblast growth factor receptor signalling pathway involved in mammary gland specification The series of molecular signals initiated by binding of a fibroblast growth factor to its receptor on the surface of al cell in the epidermis resulting in the formation of the mammary line. The mammary line is a ridge of epidermal cells that will form the mammary placodes. GO:0060596 mammary placode formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060596 The developmental process in which the mammary placode forms. The mammary placode is a transient lens shaped structure that will give rise to the mammary bud proper. GO:1901450 positive regulation of response to butan-1-ol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901450 up-regulation of response to butan-1-ol|activation of response to butan-1-ol|up regulation of response to butan-1-ol|upregulation of response to butan-1-ol Any process that activates or increases the frequency, rate or extent of response to butan-1-ol. GO:0060597 obsolete regulation of transcription from RNA polymerase II promoter involved in mammary gland formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060597 OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the formation of the mammary line, placode or bud. GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060598 primary mammary duct branching The process in which the terminal end of a mammary duct bifurcates. GO:0060599 lateral sprouting involved in mammary gland duct morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060599 mammary gland duct secondary branching The process in which a branch forms along the side of a mammary duct. GO:1901459 positive regulation of response to acetate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901459 up regulation of response to acetate|activation of response to acetate|up-regulation of response to acetate|upregulation of response to acetate Any process that activates or increases the frequency, rate or extent of response to acetate. GO:1901457 regulation of response to acetate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901457 Any process that modulates the frequency, rate or extent of response to acetate. GO:1901458 negative regulation of response to acetate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901458 down regulation of response to acetate|downregulation of response to acetate|down-regulation of response to acetate|inhibition of response to acetate Any process that stops, prevents or reduces the frequency, rate or extent of response to acetate. GO:1901455 negative regulation of response to toluene biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901455 down regulation of response to toluene|downregulation of response to toluene|down-regulation of response to toluene|inhibition of response to toluene Any process that stops, prevents or reduces the frequency, rate or extent of response to toluene. GO:1901456 positive regulation of response to toluene biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901456 upregulation of response to toluene|up regulation of response to toluene|activation of response to toluene|up-regulation of response to toluene Any process that activates or increases the frequency, rate or extent of response to toluene. GO:0060580 ventral spinal cord interneuron fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060580 The process in which a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron regardless of its environment; upon determination, the cell fate cannot be reversed. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. GO:1901453 positive regulation of response to benzene biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901453 up-regulation of response to benzene|upregulation of response to benzene|up regulation of response to benzene|activation of response to benzene Any process that activates or increases the frequency, rate or extent of response to benzene. GO:0060581 cell fate commitment involved in pattern specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060581 The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells within a field of cells that will exhibit a certain pattern of differentiation. Positional information is established through protein signals that emanate from a localized source within a developmental field resulting in specification of a cell type. Those signals are then interpreted in a cell-autonomous manner resulting in the determination of the cell type. GO:1901454 regulation of response to toluene biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901454 Any process that modulates the frequency, rate or extent of response to toluene. GO:1901451 regulation of response to benzene biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901451 Any process that modulates the frequency, rate or extent of response to benzene. GO:0060582 cell fate determination involved in pattern specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060582 A process involved in commitment of a cell to a fate in a developmental field. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment. GO:0060583 regulation of actin cortical patch localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060583 regulation of actin cortical patch localisation Any process that modulates the localization of an actin cortical patch. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells. GO:1901452 negative regulation of response to benzene biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901452 inhibition of response to benzene|down regulation of response to benzene|downregulation of response to benzene|down-regulation of response to benzene Any process that stops, prevents or reduces the frequency, rate or extent of response to benzene. GO:1901460 regulation of response to formic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901460 Any process that modulates the frequency, rate or extent of response to formic acid. GO:0060584 regulation of prostaglandin-endoperoxide synthase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060584 regulation of (PG)H synthase activity|regulation of fatty acid cyclooxygenase activity|regulation of prostaglandin synthetase activity|regulation of PG synthetase activity Any process that modulates the rate, frequency or prostaglandin-endoperoxide synthase activity. Prostaglandin-endoperoxide synthase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O. GO:1901461 negative regulation of response to formic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901461 inhibition of response to formic acid|down regulation of response to formic acid|downregulation of response to formic acid|down-regulation of response to formic acid Any process that stops, prevents or reduces the frequency, rate or extent of response to formic acid. GO:0060585 positive regulation of prostaglandin-endoperoxide synthase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060585 positive regulation of fatty acid cyclooxygenase activity|positive regulation of (PG)H synthase activity|positive regulation of PG synthetase activity|positive regulation of prostaglandin synthetase activity Any process that increases the rate, frequency or extent of prostaglandin-endoperoxide synthase activity. Prostaglandin-endoperoxide synthase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O. GO:0060586 multicellular organismal iron ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060586 Any process involved in the maintenance of the distribution of iron stores within tissues and organs of a multicellular organism. GO:0060587 regulation of lipoprotein lipid oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060587 Any process that modulates the rate, frequency or extent of lipoprotein lipid oxidation. Lipoprotein lipid oxidation is the modification of a lipoprotein by oxidation of the lipid group. GO:0060588 negative regulation of lipoprotein lipid oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060588 Any process that decreases the rate, frequency or extent of lipoprotein lipid oxidation. Lipoprotein lipid oxidation is the modification of a lipoprotein by oxidation of the lipid group. GO:0060589 nucleoside-triphosphatase regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0060589 NTPase regulator activity Modulates the rate of NTP hydrolysis by a NTPase. GO:1901468 positive regulation of ferulate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901468 upregulation of ferulate breakdown|up-regulation of ferulate degradation|upregulation of ferulate catabolic process|up regulation of ferulate catabolism|up-regulation of ferulate breakdown|activation of ferulate degradation|positive regulation of ferulate catabolism|up-regulation of ferulate catabolic process|activation of ferulate catabolic process|activation of ferulate catabolism|positive regulation of ferulate degradation|activation of ferulate breakdown|up regulation of ferulate degradation|positive regulation of ferulate breakdown|up-regulation of ferulate catabolism|up regulation of ferulate breakdown|up regulation of ferulate catabolic process|upregulation of ferulate degradation|upregulation of ferulate catabolism Any process that activates or increases the frequency, rate or extent of ferulate catabolic process. GO:1901469 regulation of syringal lignin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901469 regulation of syringal lignin breakdown|regulation of S-lignin catabolic process|regulation of syringal lignin degradation|regulation of syringal lignin catabolism Any process that modulates the frequency, rate or extent of syringal lignin catabolic process. GO:1901466 regulation of ferulate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901466 regulation of ferulate catabolism|regulation of ferulate degradation|regulation of ferulate breakdown Any process that modulates the frequency, rate or extent of ferulate catabolic process. GO:1901467 negative regulation of ferulate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901467 inhibition of ferulate degradation|down regulation of ferulate catabolic process|down regulation of ferulate catabolism|inhibition of ferulate catabolic process|inhibition of ferulate breakdown|downregulation of ferulate catabolism|negative regulation of ferulate degradation|down-regulation of ferulate degradation|down-regulation of ferulate catabolism|negative regulation of ferulate catabolism|negative regulation of ferulate breakdown|down-regulation of ferulate breakdown|downregulation of ferulate degradation|down-regulation of ferulate catabolic process|down regulation of ferulate degradation|downregulation of ferulate breakdown|inhibition of ferulate catabolism|downregulation of ferulate catabolic process|down regulation of ferulate breakdown Any process that stops, prevents or reduces the frequency, rate or extent of ferulate catabolic process. GO:1901464 negative regulation of tetrapyrrole biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901464 down regulation of tetrapyrrole anabolism|downregulation of tetrapyrrole synthesis|inhibition of tetrapyrrole biosynthesis|downregulation of tetrapyrrole formation|down regulation of tetrapyrrole synthesis|down regulation of tetrapyrrole formation|inhibition of tetrapyrrole anabolism|down regulation of tetrapyrrole biosynthetic process|down regulation of tetrapyrrole biosynthesis|inhibition of tetrapyrrole synthesis|downregulation of tetrapyrrole biosynthetic process|downregulation of tetrapyrrole biosynthesis|inhibition of tetrapyrrole formation|down-regulation of tetrapyrrole anabolism|negative regulation of tetrapyrrole anabolism|negative regulation of tetrapyrrole biosynthesis|down-regulation of tetrapyrrole biosynthetic process|down-regulation of tetrapyrrole biosynthesis|down-regulation of tetrapyrrole synthesis|negative regulation of tetrapyrrole synthesis|down-regulation of tetrapyrrole formation|negative regulation of tetrapyrrole formation|inhibition of tetrapyrrole biosynthetic process|downregulation of tetrapyrrole anabolism Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process. GO:1901465 positive regulation of tetrapyrrole biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901465 up regulation of tetrapyrrole formation|upregulation of tetrapyrrole anabolism|upregulation of tetrapyrrole biosynthetic process|upregulation of tetrapyrrole biosynthesis|upregulation of tetrapyrrole synthesis|upregulation of tetrapyrrole formation|up-regulation of tetrapyrrole anabolism|up regulation of tetrapyrrole biosynthesis|up regulation of tetrapyrrole biosynthetic process|up-regulation of tetrapyrrole synthesis|activation of tetrapyrrole biosynthetic process|positive regulation of tetrapyrrole biosynthesis|activation of tetrapyrrole anabolism|up-regulation of tetrapyrrole formation|activation of tetrapyrrole biosynthesis|activation of tetrapyrrole synthesis|positive regulation of tetrapyrrole anabolism|up regulation of tetrapyrrole anabolism|activation of tetrapyrrole formation|positive regulation of tetrapyrrole synthesis|up-regulation of tetrapyrrole biosynthetic process|up-regulation of tetrapyrrole biosynthesis|up regulation of tetrapyrrole synthesis|positive regulation of tetrapyrrole formation Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process. GO:1901462 positive regulation of response to formic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901462 up-regulation of response to formic acid|upregulation of response to formic acid|up regulation of response to formic acid|activation of response to formic acid Any process that activates or increases the frequency, rate or extent of response to formic acid. GO:1901463 regulation of tetrapyrrole biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901463 regulation of tetrapyrrole synthesis|regulation of tetrapyrrole formation|regulation of tetrapyrrole biosynthesis|regulation of tetrapyrrole anabolism Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process. GO:1901471 positive regulation of syringal lignin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901471 positive regulation of syringal lignin catabolism|upregulation of syringal lignin degradation|up-regulation of syringal lignin catabolic process|activation of S-lignin catabolic process|up regulation of syringal lignin catabolism|upregulation of syringal lignin breakdown|positive regulation of S-lignin catabolic process|up regulation of S-lignin catabolic process|upregulation of syringal lignin catabolic process|up regulation of syringal lignin degradation|upregulation of syringal lignin catabolism|positive regulation of syringal lignin degradation|up regulation of syringal lignin breakdown|positive regulation of syringal lignin breakdown|activation of syringal lignin degradation|upregulation of S-lignin catabolic process|up regulation of syringal lignin catabolic process|up-regulation of syringal lignin catabolism|activation of syringal lignin catabolic process|activation of syringal lignin breakdown|up-regulation of syringal lignin degradation|activation of syringal lignin catabolism|up-regulation of S-lignin catabolic process|up-regulation of syringal lignin breakdown Any process that activates or increases the frequency, rate or extent of syringal lignin catabolic process. GO:1901472 regulation of Golgi calcium ion export biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901472 Any process that modulates the frequency, rate or extent of Golgi calcium ion export. GO:1901470 negative regulation of syringal lignin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901470 inhibition of syringal lignin catabolic process|inhibition of syringal lignin breakdown|negative regulation of S-lignin catabolic process|down-regulation of S-lignin catabolic process|down regulation of syringal lignin degradation|downregulation of syringal lignin catabolism|downregulation of syringal lignin degradation|down regulation of syringal lignin catabolism|down regulation of syringal lignin breakdown|downregulation of S-lignin catabolic process|down regulation of syringal lignin catabolic process|downregulation of syringal lignin breakdown|down regulation of S-lignin catabolic process|inhibition of syringal lignin catabolism|downregulation of syringal lignin catabolic process|down-regulation of syringal lignin degradation|negative regulation of syringal lignin degradation|negative regulation of syringal lignin breakdown|down-regulation of syringal lignin breakdown|inhibition of S-lignin catabolic process|down-regulation of syringal lignin catabolic process|negative regulation of syringal lignin catabolism|down-regulation of syringal lignin catabolism|inhibition of syringal lignin degradation Any process that stops, prevents or reduces the frequency, rate or extent of syringal lignin catabolic process. GO:1901479 benomyl transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901479 benomyl transporter activity Enables the transfer of benomyl from one side of a membrane to the other. GO:1901477 benomyl transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901477 benomyl membrane transport The directed movement of benomyl across a membrane. GO:1901478 aminotriazole transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901478 aminotriazole transporter activity Enables the transfer of amitrole from one side of a membrane to the other. GO:1901475 pyruvate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901475 pyruvate membrane transport The directed movement of pyruvate across a membrane. GO:1901476 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1901476 GO:1901473 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1901473 GO:1901474 azole transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901474 azole transporter activity Enables the directed movement of azoles, heterocyclic compound found in many biologically important substances, from one side of a membrane to the other. GO:0035595 N-acetylglucosaminylinositol deacetylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035595 EC:3.5.1.103|KEGG_REACTION:R09651|RHEA:26180|MetaCyc:RXN1G-2 1-(2-acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol acetylhydrolase activity|1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase activity|GlcNAc-Ins deacetylase activity|N-acetyl-1D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase activity Catalysis of the reaction: 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside + H2O = 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside + acetate. This reaction is the hydrolysis of an acetyl group from N-acetylglucosaminylinositol. GO:1901482 L-lysine import into vacuole involved in cellular response to nitrogen starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901482 A L-lysine import into the vacuole that is involved in cellular response to nitrogen starvation. GO:1901483 regulation of transcription factor catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901483 regulation of transcription factor breakdown|regulation of proteasome-mediated transcription factor catabolism|regulation of transcription factor catabolism|regulation of transcription factor degradation|regulation of sequence-specific DNA binding transcription factor catabolic process Any process that modulates the frequency, rate or extent of transcription factor catabolic process. GO:0035596 methylthiotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035596 MTTase Catalysis of the addition of a methylthioether group (-SCH3) to a nucleic acid or protein acceptor. GO:0035597 N6-isopentenyladenosine methylthiotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035597 i6A methylthiotransferase activity Catalysis of the methylthiolation (-SCH3 addition) at the C2 of the adenosine ring of N6-isopentenyladenosine (i6A) in tRNA, to form 2-methylthio-N6-isopentenyladenosine (ms2i6A). GO:1901480 oleate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901480 RHEA:33655 oleate transporter activity Enables the transfer of oleate from one side of a membrane to the other. GO:0035598 N6-threonylcarbomyladenosine methylthiotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035598 Reactome:R-HSA-6786571 t6A methylthiotransferase activity Catalysis of the methylthiolation (-SCH3 addition) at the C2 of the adenosine ring of N6-threonylcarbomyladenosine (t6A) in tRNA, to form 2-methylthio-N6-threonylcarbamoyladenosine (ms2t6A). GO:1901481 L-glutamate import involved in cellular response to nitrogen starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901481 L-glutamate uptake involved in cellular response to nitrogen starvation Any L-glutamate import that is involved in cellular response to nitrogen starvation. GO:0035599 aspartic acid methylthiotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035599 RESID:AA0232 Catalysis of the methylthiolation (-SCH3 addition) of the beta-carbon of peptidyl-aspartic acid to form peptidyl-L-beta-methylthioaspartic acid. GO:0035590 purinergic nucleotide receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035590 purinergic receptor signalling pathway|purinoceptor signaling pathway|purinergic receptor signaling pathway|P2 receptor signaling pathway|purinergic nucleotide receptor signalling pathway The series of molecular signals generated as a consequence of a receptor binding to an extracellular purine nucleotide to initiate a change in cell activity. GO:0035591 signaling adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035591 signaling scaffold activity|signalling adaptor activity The binding activity of a molecule that brings together two or more molecules in a signaling pathway, permitting those molecules to function in a coordinated way. Adaptor molecules themselves do not have catalytic activity. GO:0035592 establishment of protein localization to extracellular region biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035592 establishment of protein localisation in extracellular region|establishment of protein localization in extracellular region The directed movement of a protein to a specific location within the extracellular region. GO:0035593 positive regulation of Wnt signaling pathway by establishment of Wnt protein localization to extracellular region biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035593 positive regulation of Wnt receptor signaling pathway by establishment of Wnt protein localisation in extracellular region|positive regulation of Wnt signaling range|positive regulation of Wnt receptor signaling pathway by establishment of Wnt protein localization in extracellular region|positive regulation of Wnt diffusion|positive regulation of Wnt-activated signaling pathway by establishment of Wnt protein localization to extracellular region|positive regulation of Wnt receptor signalling pathway by establishment of Wnt protein localization in extracellular region|positive regulation of Wnt receptor signaling pathway by establishment of Wnt protein localization to extracellular region Any process that activates or increases the frequency, rate or extent of the Wnt signaling pathway by the directed movement of a Wnt protein within the extracellular region. GO:0035594 ganglioside binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035594 Interacting selectively and non-covalently with a ganglioside, a ceramide oligosaccharide carrying in addition to other sugar residues, one or more sialic acid residues. GO:1901488 obsolete positive regulation of SREBP signaling pathway by negative regulation of transcription factor catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901488 positive regulation of SREBP signaling pathway by inhibition of SREBP degradation|positive regulation of SREBP-mediated signaling pathway by negative regulation of transcription factor catabolic process|positive regulation of SREBP-mediated signalling pathway by negative regulation of transcription factor catabolic process|positive regulation of SREBP signaling pathway by negative regulation of SREBP degradation|positive regulation of SREBP signaling pathway by negative regulation of transcription factor catabolism OBSOLETE. Negative regulation of transcription factor catabolism that results in positive regulation of the SREBP signaling pathway. GO:1901489 obsolete positive regulation of SREBP signaling pathway by negative regulation of transcription factor catabolic process in response to decreased oxygen levels biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901489 positive regulation of SREBP signaling pathway by negative regulation of SREBP degradation, in response to decreased oxygen|positive regulation of SREBP-mediated signaling pathway in absence of oxygen by negative regulation of transcription factor catabolic process|positive regulation of SREBP signaling by negative regulation of transcription factor catabolism at low oxygen levels|positive regulation of SREBP-mediated signaling pathway in response to decreased oxygen levels by negative regulation of transcription factor catabolic process|positive regulation of SREBP signaling by inhibition of SREBP degradation in response to decreased oxygen levels OBSOLETE. Negative regulation of transcription factor catabolism in response to decreased oxygen levels, which results in positive regulation of the SREBP signaling pathway. GO:1901486 obsolete negative regulation of SREBP signaling pathway by positive regulation of transcription factor catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901486 negative regulation of SREBP-mediated signalling pathway by positive regulation of transcription factor catabolic process|negative regulation of SREBP signaling pathway by positive regulation of SREBP degradation|negative regulation of SREBP-mediated signaling pathway by positive regulation of transcription factor catabolic process|negative regulation of SREBP signaling pathway by positive regulation of transcription factor catabolism OBSOLETE. Positive regulation of transcription factor catabolism that results in negative regulation of the SREBP signaling pathway. GO:1901487 obsolete negative regulation of SREBP signaling pathway by positive regulation of transcription factor catabolic process in response to increased oxygen levels biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901487 negative regulation of SREBP signaling pathway by positive regulation of SREBP degradation, in response to elevated oxygen|negative regulation of SREBP-mediated signaling pathway in response to increased oxygen levels by positive regulation of transcription factor catabolic process|negative regulation of SREBP signaling by acceleration of SREBP degradation, in response to increased oxygen levels|negative regulation of SREBP signaling by positive regulation of transcription factor catabolism in response to increased oxygen levels|negative regulation of SREBP-mediated signaling pathway in presence of oxygen by positive regulation of transcription factor catabolic process OBSOLETE. Positive regulation of transcription factor catabolism in response to increased oxygen levels, which results in negative regulation of the SREBP signaling pathway. GO:1901484 negative regulation of transcription factor catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901484 down regulation of sequence-specific DNA binding transcription factor catabolic process|down regulation of transcription factor breakdown|downregulation of transcription factor catabolic process|inhibition of transcription factor degradation|inhibition of proteasome-mediated transcription factor catabolism|down regulation of transcription factor catabolic process|inhibition of sequence-specific DNA binding transcription factor catabolic process|inhibition of transcription factor catabolic process|inhibition of transcription factor breakdown|inhibition of transcription factor catabolism|down regulation of proteasome-mediated transcription factor catabolism|downregulation of proteasome-mediated transcription factor catabolism|down-regulation of transcription factor degradation|down regulation of transcription factor catabolism|negative regulation of transcription factor degradation|negative regulation of sequence-specific DNA binding transcription factor catabolic process|down-regulation of sequence-specific DNA binding transcription factor catabolic process|downregulation of transcription factor catabolism|negative regulation of transcription factor breakdown|down-regulation of transcription factor breakdown|negative regulation of proteasome-mediated transcription factor catabolism|down-regulation of proteasome-mediated transcription factor catabolism|downregulation of transcription factor degradation|down-regulation of transcription factor catabolic process|downregulation of sequence-specific DNA binding transcription factor catabolic process|negative regulation of transcription factor catabolism|down-regulation of transcription factor catabolism|down regulation of transcription factor degradation|downregulation of transcription factor breakdown Any process that stops, prevents or reduces the frequency, rate or extent of transcription factor catabolic process. GO:1901485 positive regulation of transcription factor catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901485 activation of transcription factor catabolism|up regulation of transcription factor catabolic process|up-regulation of proteasome-mediated transcription factor catabolism|upregulation of transcription factor degradation|upregulation of sequence-specific DNA binding transcription factor catabolic process|up-regulation of transcription factor catabolism|upregulation of transcription factor breakdown|upregulation of proteasome-mediated transcription factor catabolism|up-regulation of transcription factor degradation|upregulation of transcription factor catabolic process|up-regulation of sequence-specific DNA binding transcription factor catabolic process|upregulation of transcription factor catabolism|up-regulation of transcription factor breakdown|activation of transcription factor degradation|up regulation of proteasome-mediated transcription factor catabolism|up-regulation of transcription factor catabolic process|activation of sequence-specific DNA binding transcription factor catabolic process|activation of transcription factor catabolic process|positive regulation of proteasome-mediated transcription factor catabolism|activation of transcription factor breakdown|positive regulation of transcription factor degradation|up regulation of transcription factor degradation|positive regulation of sequence-specific DNA binding transcription factor catabolic process|up regulation of transcription factor catabolism|positive regulation of transcription factor catabolism|up regulation of sequence-specific DNA binding transcription factor catabolic process|positive regulation of transcription factor breakdown|activation of proteasome-mediated transcription factor catabolism|up regulation of transcription factor breakdown Any process that activates or increases the frequency, rate or extent of transcription factor catabolic process. GO:1901493 response to decalin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901493 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a decalin stimulus. GO:0035584 calcium-mediated signaling using intracellular calcium source biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035584 calcium signaling using intracellular calcium source|calcium-mediated signalling using intracellular calcium source|calcium signalling using intracellular calcium source A series of molecular signals in which a cell uses calcium ions released from an intracellular store to convert a signal into a response. GO:0035585 calcium-mediated signaling using extracellular calcium source biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035585 calcium-mediated signalling using extracellular calcium source|extracellular calcium influx|calcium signalling using extracellular calcium source|calcium signaling using extracellular calcium source A series of molecular signals in which a cell uses calcium ions imported from an extracellular source to convert a signal into a response. GO:1901494 regulation of cysteine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901494 regulation of cysteine metabolism Any process that modulates the frequency, rate or extent of cysteine metabolic process. GO:1901491 negative regulation of lymphangiogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901491 inhibition of lymph vessel formation|inhibition of lymphangiogenesis|down regulation of lymphangiogenesis|negative regulation of lymph vessel formation|down-regulation of lymph vessel formation|downregulation of lymphangiogenesis|downregulation of lymph vessel formation|down-regulation of lymphangiogenesis|down regulation of lymph vessel formation Any process that stops, prevents or reduces the frequency, rate or extent of lymphangiogenesis. GO:0035586 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035586 GO:0035587 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035587 GO:1901492 positive regulation of lymphangiogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901492 upregulation of lymph vessel formation|up-regulation of lymphangiogenesis|up-regulation of lymph vessel formation|activation of lymph vessel formation|upregulation of lymphangiogenesis|positive regulation of lymph vessel formation|up regulation of lymphangiogenesis|activation of lymphangiogenesis|up regulation of lymph vessel formation Any process that activates or increases the frequency, rate or extent of lymphangiogenesis. GO:0035588 G protein-coupled purinergic receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035588 G-protein coupled purinergic receptor signaling pathway|G-protein coupled purinergic receptor signalling pathway The series of molecular signals generated as a consequence of a receptor binding to an extracellular purine or purine derivative and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity. GO:1901490 regulation of lymphangiogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901490 regulation of lymph vessel formation Any process that modulates the frequency, rate or extent of lymphangiogenesis. GO:0035589 G protein-coupled purinergic nucleotide receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035589 G-protein coupled purinergic nucleotide receptor signalling pathway|G-protein coupled purinergic nucleotide receptor signaling pathway|P2Y receptor signaling pathway The series of molecular signals generated as a consequence of a receptor binding to an extracellular purine nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity. GO:0035580 specific granule lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035580 secondary granule lumen The volume enclosed by the membrane of a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase. GO:0035581 sequestering of extracellular ligand from receptor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035581 negative regulation of protein bioavailability|extracellular sequestering of receptor ligand The process of binding or confining an extracellular signaling ligand, such that the ligand is unable to bind to its cell surface receptor. GO:0035582 sequestering of BMP in extracellular matrix biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035582 negative regulation of bone morphogenetic protein signaling pathway by extracellular matrix sequestering of bone morphogenetic protein|BMP sequestration in the ECM|negative regulation of BMP signaling pathway by extracellular sequestering of BMP|negative regulation of BMP signalling pathway by extracellular matrix sequestering of BMP Confining a bone morphogenetic protein (BMP) to the extracellular matrix (ECM), such that it is separated from other components of the signaling pathway, including its cell surface receptor. Bone morphogenetic proteins (BMPs) are secreted as homodimers, non-covalently associated with N-terminal pro-peptides, and are targeted to the extracellular matrix through interaction with matrix proteins. GO:0035583 sequestering of TGFbeta in extracellular matrix biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035583 negative regulation of transforming growth factor beta receptor signalling pathway by extracellular matrix sequestering of TGFbeta|negative regulation of transforming growth factor beta receptor signaling pathway by extracellular matrix sequestering of TGFbeta|sequestering of TGFbeta large latency complex in extracellular matrix|sequestering of TGFbeta LLC in extracellular matrix Confining TGFbeta to the extracellular matrix (ECM) such that it is separated from other components of the signaling pathway, including its cell surface receptor. TGFbeta is secreted as part of a latent complex that is targeted to the extracellular matrix through latent-TGFbeta-binding protein (LTBP)-mediated association with matrix proteins. GO:1901499 response to hexane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901499 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexane stimulus. GO:1901497 response to diphenyl ether biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901497 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diphenyl ether stimulus. GO:1901498 response to tetralin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901498 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetralin stimulus. GO:1901495 negative regulation of cysteine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901495 negative regulation of cysteine metabolism|down-regulation of cysteine metabolism|down-regulation of cysteine metabolic process|inhibition of cysteine metabolism|downregulation of cysteine metabolic process|down regulation of cysteine metabolic process|down regulation of cysteine metabolism|inhibition of cysteine metabolic process|downregulation of cysteine metabolism Any process that stops, prevents or reduces the frequency, rate or extent of cysteine metabolic process. GO:1901496 positive regulation of cysteine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901496 up regulation of cysteine metabolism|positive regulation of cysteine metabolism|activation of cysteine metabolism|up-regulation of cysteine metabolic process|activation of cysteine metabolic process|up-regulation of cysteine metabolism|up regulation of cysteine metabolic process|upregulation of cysteine metabolism|upregulation of cysteine metabolic process Any process that activates or increases the frequency, rate or extent of cysteine metabolic process. GO:0035573 N-terminal peptidyl-serine trimethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035573 The trimethylation of the N-terminal serine of proteins to form the derivative N,N,N-trimethylserine. GO:0035574 histone H4-K20 demethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035574 The modification of histone H4 by the removal of a methyl group from lysine at position 20 of the histone. GO:0035575 histone demethylase activity (H4-K20 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035575 Reactome:R-HSA-2172678 Catalysis of the reaction: histone H4 N6-methyl-L-lysine (position 20) + 2-oxoglutarate + O2 = histone H4 L-lysine (position 20) + succinate + formaldehyde + CO2. This reaction is the removal of a methyl group from lysine at position 20 of the histone H4 protein. GO:0035576 retinoic acid receptor signaling pathway involved in pronephric field specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035576 retinoic acid receptor signalling pathway involved in pronephric field specification The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that results in regions of the embryo being delineated into the area in which the pronephric kidney will develop. GO:0035577 azurophil granule membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035577 primary granule membrane The lipid bilayer surrounding an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid. GO:0035578 azurophil granule lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035578 primary granule lumen The volume enclosed by the membrane of an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid. GO:0035579 specific granule membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035579 secondary granule membrane The lipid bilayer surrounding a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase. GO:0035570 N-terminal peptidyl-serine methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035570 The methylation of the N-terminal serine of proteins. GO:0035571 N-terminal peptidyl-serine monomethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035571 The monomethylation of the N-terminal serine of proteins to form the derivative N-methylserine. GO:0035572 N-terminal peptidyl-serine dimethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035572 The dimethylation of the N-terminal serine of proteins to form the derivative N,N-dimethylserine. GO:0035562 negative regulation of chromatin binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035562 Any process that stops or reduces the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase. GO:0035563 positive regulation of chromatin binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035563 Any process that increases the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase. GO:0035564 regulation of kidney size biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035564 Any process that modulates the size of a kidney. GO:0035565 regulation of pronephros size biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035565 regulation of pronephric kidney size Any process that modulates the size of a pronephric kidney. GO:0035566 regulation of metanephros size biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035566 regulation of metanephric kidney size Any process that modulates the size of a metanephric kidney. GO:0035567 non-canonical Wnt signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035567 beta-catenin-independent Wnt receptor signaling pathway|non-canonical Wnt receptor signalling pathway|non-canonical Wnt receptor signaling pathway|non-canonical Wnt-activated signaling pathway The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin. GO:0035568 N-terminal peptidyl-proline methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035568 RESID:AA0419 The methylation of the N-terminal proline of proteins. GO:0035569 obsolete N-terminal peptidyl-proline trimethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035569 N-terminal peptidyl-proline trimethylation OBSOLETE. The trimethylation of the N-terminal proline of proteins to form the derivative N,N,N-trimethylproline. GO:0035560 pheophoridase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035560 EC:3.1.1.82|RHEA:32483 phedase activity|PPD activity Catalysis of the reaction: pheophorbide a + H2O = pyropheophorbide a + methanol + CO2. The reaction occurs in two steps; pheophoridase catalyzes the conversion of pheophorbide a to a precursor of pyropheophorbide a, C-13(2)-carboxylpyropheophorbide a, by demethylation, and then the precursor is decarboxylated non-enzymatically to yield pyropheophorbide a. GO:0035561 regulation of chromatin binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035561 Any process that modulates the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase. GO:0035559 obsolete MAPKKK cascade involved in epidermal growth factor receptor signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035559 MAPKKK cascade involved in signaling from the EGFR|MAPKKK cascade involved in epidermal growth factor receptor signalling|MAPKKK cascade involved in epidermal growth factor receptor signaling OBSOLETE. The process in which a signal is passed from the epidermal growth factor receptor (EGFR) to components of the MAPKKK cascade, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. GO:0035551 protein initiator methionine removal involved in protein maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035551 Removal of the initiating methionine or formylmethionine residue from a protein that contributes to protein maturation, the attainment of the full functional capacity of a protein. GO:0035552 oxidative single-stranded DNA demethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035552 oxidative ssDNA demethylation Removal of the methyl group from one or more nucleotides within a single-stranded DNA molecule involving the oxidation (i.e. electron loss) of one or more atoms. GO:0035553 oxidative single-stranded RNA demethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035553 oxidative ssRNA demethylation Removal of the methyl group from one or more nucleotides within a single-stranded RNA molecule involving the oxidation (i.e. electron loss) of one or more atoms. GO:0035554 termination of Roundabout signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035554 The signaling process in which signaling from the receptor ROBO is brought to an end, rather than being reversibly modulated. GO:0035555 obsolete initiation of Roundabout signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035555 initiation of Roundabout signal transduction OBSOLETE. The process in which a SLIT protein causes activation of the receptor, Roundabout (ROBO). GO:0035556 intracellular signal transduction biolink:BiologicalProcess go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0035556 signal transduction via intracellular signaling cascade|protein kinase cascade|intracellular signaling chain|intracellular signal transduction pathway|signal transmission via intracellular cascade|intracellular signaling cascade|intracellular protein kinase cascade|intracellular signaling pathway The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. GO:0035557 obsolete intracellular signal transduction involved in cell surface receptor linked signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035557 intracellular signaling chain involved in cell surface receptor signaling|intracellular signaling cascade involved in cell surface receptor linked signaling|intracellular signal transduction involved in cell surface receptor linked signalling|intracellular signal transduction involved in cell surface receptor linked signaling OBSOLETE. The process in which a signal is passed on from a receptor at the cell surface to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. GO:0035558 obsolete phosphatidylinositol 3-kinase cascade involved in insulin receptor signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035558 phosphoinositide 3-kinase cascade involved in insulin receptor signaling|phosphatidylinositol 3-kinase cascade involved in insulin receptor signalling|PI3K cascade involved in signaling from the insulin receptor|phosphatidylinositol 3-kinase cascade involved in insulin receptor signaling|phosphoinositide 3-kinase cascade involved in insulin receptor signalling OBSOLETE. The process in which a signal is passed from the insulin receptor to components of the phosphatidylinositol 3-kinase (PI3K) cascade, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. GO:0035550 urease complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035550 A multiprotein nickel-containing complex that possesses urease activity (catalysis of the hydrolysis of urea to ammonia and carbon dioxide). CHEBI:36628 1,8-naphthyridine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36628 UBERON:0013498 vestibulo-cochlear VIII ganglion complex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013498 vestibular VIII ganglion complex|vestibulocochlear VIII ganglion complex|vestibulocochlear ganglion complex CHEBI:36622 benzimidazole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36622 GO:0060510 type II pneumocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060510 granular pneumocyte differentiation|large alveolar cell differentiation|great alveolar cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a type II pneumocyte. A type II pneumocyte is a surfactant secreting cell that contains abundant cytoplasm containing numerous lipid-rich multilamellar bodies. GO:0060511 creation of an inductive signal by a mesenchymal cell involved in lung induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060511 The process in which splanchnic mesenchymal cells send a signal over a short range to endodermal cells inducing them to form the primary lung bud. GO:0060512 prostate gland morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060512 The process in which the anatomical structures of a prostate gland are generated and organized. GO:0060513 prostatic bud formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060513 prostate gland formation|primary prostate bud formation|prostate ductal budding The morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth. CHEBI:36623 4H-benzimidazole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36623 GO:0060514 prostate induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060514 The close range interaction of the urogenital sinus mesenchyme and the urogenital sinus epithelium that causes the cells of the urogenital sinus epithelium to change their fates and specify the development of the prostate gland. CHEBI:36624 naphthyridine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36624 GO:0060515 prostate field specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060515 The process that results in the delineation of a specific region of the urogenital sinus epithelium into the area in which the prostate gland will develop. GO:0060516 primary prostatic bud elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060516 prostate bud elongation involved in prostate morphogenesis|prostate bud elongation The increase in size of the prostatic bud as it forms. GO:0060517 epithelial cell proliferation involved in prostatic bud elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060517 The multiplication of epithelial cells, contributing to the expansion of the primary prostatic bud. GO:0060518 cell migration involved in prostatic bud elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060518 The orderly movement of epithelial cells from one site to another contributing to the elongation of the primary prostatic bud. GO:0060519 cell adhesion involved in prostatic bud elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060519 The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the elongation of the primary prostatic bud. CHEBI:36638 fucosyl glycosphingolipid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36638 CHEBI:36639 2H-benzimidazole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36639 GO:0060500 obsolete regulation of transcription from RNA polymerase II promoter involved in lung bud formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060500 OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the branching morphogenesis by which the initial primordium of the lung is formed. GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060501 Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung attaining its shape. GO:0060502 epithelial cell proliferation involved in lung morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060502 The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the lung. GO:0060503 bud dilation involved in lung branching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060503 bud expansion The process in which a bud in the lung increases radially. CHEBI:36635 p-toluic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36635 GO:0060504 positive regulation of epithelial cell proliferation involved in lung bud dilation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060504 Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung bud increasing in size radially. GO:0060505 epithelial cell proliferation involved in lung bud dilation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060505 The multiplication or reproduction of epithelial cells that contribute to the radial growth of a lung bud. GO:0060506 smoothened signaling pathway involved in lung development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060506 hedgehog signaling pathway involved in lung development|hh signaling pathway involved in lung development|smoothened signalling pathway involved in lung development The series of molecular signals generated as a consequence of activation of the transmembrane Smoothened-type protein. This process contributes to lung development. GO:0060507 epidermal growth factor receptor signaling pathway involved in lung development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060507 epidermal growth factor receptor signalling pathway involved in lung development The series of molecular signals generated as a consequence of an epidermal growth factor-type receptor binding to one of its physiological ligands. This process contributes to lung development. GO:0060508 lung basal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060508 pulmonary basal cell differentiation The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature basal cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate. A basal cell is an epithelial stem cell. GO:0060509 type I pneumocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060509 squamous alveolar cell differentiation|membranous pneumocyte differentiation|small alveolar cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a type I pneumocyte. A type I pneumocyte is a flattened cell with greatly attenuated cytoplasm and a paucity of organelles. CHEBI:36607 cyclic acid anhydride biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36607 CHEBI:36608 acyclic acid anhydride biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36608 UBERON:0013478 cecal tonsil biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013478 caecal tonsil|cecal GALT A thickened round patch of lymphoid tissue located at the ileocecal junction adjacent to the sacculus rotundus. UBERON:0013479 lung endothelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013479 respiratory endothelium A blood vessel endothelium that is part of a lung [Automatically generated definition]. CHEBI:36606 acid anhydride biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36606 CHEBI:36609 cyclic dicarboxylic anhydride biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36609 GO:0060530 smooth muscle cell differentiation involved in prostate glandular acinus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060530 The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the prostate glandular acinus. GO:0060531 neuroendocrine cell differentiation involved in prostate gland acinus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060531 The process in which relatively unspecialized cells acquires specialized structural and functions of a neuroendocrine cell of the prostate gland acinus. GO:0060532 bronchus cartilage development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060532 pulmonary cartilage development The process whose specific outcome is the progression of lung cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. GO:0060533 bronchus cartilage morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060533 The process in which the bronchus cartilage is generated and organized. The bronchus cartilage is the connective tissue of the portion of the airway that connects to the lungs. GO:0060534 trachea cartilage development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060534 The process whose specific outcome is the progression of the tracheal cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. GO:0060535 trachea cartilage morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060535 The process in which the anatomical structures of cartilage in the trachea are generated and organized. CHEBI:36602 2-dehydro-L-idonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36602 GO:0060536 cartilage morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060536 The process in which the anatomical structures of cartilage are generated and organized. GO:0060537 muscle tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060537 The progression of muscle tissue over time, from its initial formation to its mature state. Muscle tissue is a contractile tissue made up of actin and myosin fibers. GO:0060538 skeletal muscle organ development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060538 The progression of a skeletal muscle organ over time from its initial formation to its mature state. A skeletal muscle organ includes the skeletal muscle tissue and its associated connective tissue. GO:0060539 diaphragm development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060539 The progression of the diaphragm over time from its initial formation to the mature structure. The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs. CHEBI:36611 fenchane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36611 GO:0060520 activation of prostate induction by androgen receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060520 activation of prostate induction by androgen receptor signalling pathway Any series of molecular signals generated as a consequence of an androgen binding to its receptor in the urogenital sinus mesenchyme that initiates prostate induction. Prostate induction is the close range interaction of the urogenital sinus mesenchyme and the urogenital sinus epithelium that causes the cells of the urogenital sinus epithelium to change their fates and specify the development of the prostate gland. GO:0060521 mesenchymal-epithelial cell signaling involved in prostate induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060521 mesenchymal-epithelial cell signalling involved in prostate induction Signaling at short range from urogenital sinus mesenchymal cells to cells of the urogenital epithelium resulting in the epithelial cells adopting a prostatic fate. GO:0060522 inductive mesenchymal to epithelial cell signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060522 inductive mesenchymal to epithelial cell signalling Signaling at short range from mesenchymal cells to cells of an epithelium that results in a developmental change in the epithelial cells. GO:0060523 prostate epithelial cord elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060523 The developmental growth process in which solid chords of prostate epithelium increase in length. CHEBI:36615 triterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36615 GO:0060524 dichotomous subdivision of prostate epithelial cord terminal unit biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060524 prostate epithelial cord bifurcation The process in which a prostate epithelial cord bifurcates at its end. CHEBI:36612 (1R,4S)-fenchone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36612 GO:0060525 prostate glandular acinus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060525 The progression of a glandular acinus of the prostate gland over time, from its initial formation to the mature structure. The glandular acini are the saclike structures of the gland. GO:0060526 prostate glandular acinus morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060526 The process in which the prostate glandular acini are generated and organized. The glandular acini are the saclike structures of the gland. GO:0060527 prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060527 The branching morphogenesis process in which the prostate epithelial cords branch freely to create the structure of the prostate acini. GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060528 The process in which a relatively unspecialized epithelial cell acquires specialized features of a secretory columnal luminar epithelial cell of the prostate. GO:0060529 squamous basal epithelial stem cell differentiation involved in prostate gland acinus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060529 The process in which a relatively unspecialized epithelial cell acquires specialized features of a squamous basal epithelial stem cell of the prostate. GO:1901408 negative regulation of phosphorylation of RNA polymerase II C-terminal domain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901408 down regulation of generation of II(0) form of RNA polymerase II|downregulation of hyperphosphorylation of RNA polymerase II C-terminal domain|downregulation of phosphorylation of RNA polymerase II C-terminal domain|downregulation of generation of II(0) form of RNA polymerase II|down-regulation of CTD domain phosphorylation of RNA polymerase II|negative regulation of CTD domain phosphorylation of RNA polymerase II|negative regulation of generation of hyperphosphorylated CTD of RNA polymerase II|down-regulation of generation of hyperphosphorylated CTD of RNA polymerase II|down regulation of phosphorylation of RNA polymerase II C-terminal domain|inhibition of phosphorylation of RNA polymerase II C-terminal domain|negative regulation of hyperphosphorylation of RNA polymerase II C-terminal domain|down-regulation of hyperphosphorylation of RNA polymerase II C-terminal domain|negative regulation of generation of II(0) form of RNA polymerase II|down-regulation of generation of II(0) form of RNA polymerase II|downregulation of generation of hyperphosphorylated CTD of RNA polymerase II|inhibition of CTD domain phosphorylation of RNA polymerase II|down regulation of generation of hyperphosphorylated CTD of RNA polymerase II|inhibition of hyperphosphorylation of RNA polymerase II C-terminal domain|down regulation of CTD domain phosphorylation of RNA polymerase II|inhibition of generation of II(0) form of RNA polymerase II|down-regulation of phosphorylation of RNA polymerase II C-terminal domain|inhibition of generation of hyperphosphorylated CTD of RNA polymerase II|downregulation of CTD domain phosphorylation of RNA polymerase II|down regulation of hyperphosphorylation of RNA polymerase II C-terminal domain Any process that stops, prevents or reduces the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain. GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901409 up regulation of CTD domain phosphorylation of RNA polymerase II|up-regulation of generation of hyperphosphorylated CTD of RNA polymerase II|up regulation of phosphorylation of RNA polymerase II C-terminal domain|positive regulation of CTD domain phosphorylation of RNA polymerase II|up regulation of hyperphosphorylation of RNA polymerase II C-terminal domain|activation of generation of hyperphosphorylated CTD of RNA polymerase II|positive regulation of hyperphosphorylation of RNA polymerase II C-terminal domain|activation of CTD domain phosphorylation of RNA polymerase II|up regulation of generation of II(0) form of RNA polymerase II|positive regulation of generation of II(0) form of RNA polymerase II|upregulation of phosphorylation of RNA polymerase II C-terminal domain|positive regulation of generation of hyperphosphorylated CTD of RNA polymerase II|activation of hyperphosphorylation of RNA polymerase II C-terminal domain|up-regulation of CTD domain phosphorylation of RNA polymerase II|up regulation of generation of hyperphosphorylated CTD of RNA polymerase II|activation of generation of II(0) form of RNA polymerase II|up-regulation of hyperphosphorylation of RNA polymerase II C-terminal domain|up-regulation of phosphorylation of RNA polymerase II C-terminal domain|up-regulation of generation of II(0) form of RNA polymerase II|activation of phosphorylation of RNA polymerase II C-terminal domain|upregulation of CTD domain phosphorylation of RNA polymerase II|upregulation of generation of hyperphosphorylated CTD of RNA polymerase II|upregulation of hyperphosphorylation of RNA polymerase II C-terminal domain|upregulation of generation of II(0) form of RNA polymerase II Any process that activates or increases the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain. GO:1901406 positive regulation of tetrapyrrole catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901406 activation of tetrapyrrole catabolism|up regulation of tetrapyrrole catabolic process|upregulation of tetrapyrrole degradation|up-regulation of tetrapyrrole catabolism|upregulation of tetrapyrrole breakdown|upregulation of tetrapyrrole catabolic process|up-regulation of tetrapyrrole degradation|upregulation of tetrapyrrole catabolism|up-regulation of tetrapyrrole breakdown|activation of tetrapyrrole degradation|up-regulation of tetrapyrrole catabolic process|activation of tetrapyrrole catabolic process|positive regulation of tetrapyrrole degradation|activation of tetrapyrrole breakdown|up regulation of tetrapyrrole degradation|up regulation of tetrapyrrole catabolism|positive regulation of tetrapyrrole catabolism|positive regulation of tetrapyrrole breakdown|up regulation of tetrapyrrole breakdown Any process that activates or increases the frequency, rate or extent of tetrapyrrole catabolic process. GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901407 regulation of hyperphosphorylation of RNA polymerase II C-terminal domain|regulation of generation of II(0) form of RNA polymerase II|regulation of generation of hyperphosphorylated CTD of RNA polymerase II|regulation of CTD domain phosphorylation of RNA polymerase II Any process that modulates the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain. GO:1901404 regulation of tetrapyrrole catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901404 regulation of tetrapyrrole breakdown|regulation of tetrapyrrole catabolism|regulation of tetrapyrrole degradation Any process that modulates the frequency, rate or extent of tetrapyrrole catabolic process. GO:1901405 negative regulation of tetrapyrrole catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901405 down regulation of tetrapyrrole breakdown|downregulation of tetrapyrrole catabolic process|inhibition of tetrapyrrole degradation|down regulation of tetrapyrrole catabolic process|inhibition of tetrapyrrole catabolic process|inhibition of tetrapyrrole breakdown|inhibition of tetrapyrrole catabolism|negative regulation of tetrapyrrole degradation|down regulation of tetrapyrrole catabolism|down-regulation of tetrapyrrole degradation|downregulation of tetrapyrrole catabolism|negative regulation of tetrapyrrole breakdown|down-regulation of tetrapyrrole breakdown|down-regulation of tetrapyrrole catabolic process|downregulation of tetrapyrrole degradation|down regulation of tetrapyrrole degradation|down-regulation of tetrapyrrole catabolism|negative regulation of tetrapyrrole catabolism|downregulation of tetrapyrrole breakdown Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole catabolic process. GO:1901402 negative regulation of tetrapyrrole metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901402 down regulation of tetrapyrrole metabolic process|inhibition of tetrapyrrole metabolic process|down-regulation of tetrapyrrole metabolism|negative regulation of tetrapyrrole metabolism|inhibition of tetrapyrrole metabolism|down-regulation of tetrapyrrole metabolic process|down regulation of tetrapyrrole metabolism|downregulation of tetrapyrrole metabolism|downregulation of tetrapyrrole metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole metabolic process. GO:1901403 positive regulation of tetrapyrrole metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901403 upregulation of tetrapyrrole metabolic process|activation of tetrapyrrole metabolism|up-regulation of tetrapyrrole metabolism|up-regulation of tetrapyrrole metabolic process|activation of tetrapyrrole metabolic process|upregulation of tetrapyrrole metabolism|up regulation of tetrapyrrole metabolic process|up regulation of tetrapyrrole metabolism|positive regulation of tetrapyrrole metabolism Any process that activates or increases the frequency, rate or extent of tetrapyrrole metabolic process. GO:1901400 positive regulation of transforming growth factor beta3 activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901400 upregulation of TGFB3 activation|positive regulation of TGF-beta 3 activation|activation of TGFbeta 3 activation|up regulation of transforming growth factor beta3 activation|activation of transforming growth factor beta3 activation|activation of TGF-beta 3 activation|positive regulation of TGFbeta 3 activation|up regulation of TGFbeta 3 activation|up-regulation of TGFB3 activation|up-regulation of TGF-beta 3 activation|activation of TGFB3 activation|up-regulation of transforming growth factor beta3 activation|upregulation of TGFbeta 3 activation|positive regulation of TGFB3 activation|upregulation of TGF-beta 3 activation|up regulation of TGFB3 activation|upregulation of transforming growth factor beta3 activation|up-regulation of TGFbeta 3 activation|up regulation of TGF-beta 3 activation Any process that activates or increases the frequency, rate or extent of transforming growth factor beta3 activation. GO:1901401 regulation of tetrapyrrole metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901401 regulation of tetrapyrrole metabolism Any process that modulates the frequency, rate or extent of tetrapyrrole metabolic process. GO:0060550 positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060550 Any process that increases the rate, frequency or extent of fructose 1,6-bisphosphate 1-phosphatase activity. Fructose 1,6-bisphosphate 1-phosphatase activity is the catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. GO:0060551 regulation of fructose 1,6-bisphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060551 Any process that modulates the rate, frequency or extent of fructose 1,6-bisphosphate metabolism. Fructose 1,6-bisphosphate metabolism is the chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis. GO:0060552 positive regulation of fructose 1,6-bisphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060552 Any process that increases the rate, frequency or extent of fructose 1,6-bisphosphate metabolism. Fructose 1,6-bisphosphate metabolism is the chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis. GO:0060553 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0060553 GO:0060554 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0060554 GO:0060555 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0060555 GO:0060556 regulation of vitamin D biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060556 Any process that modulates the rate frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3). GO:0060557 positive regulation of vitamin D biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060557 Any process that increases the rate, frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3). GO:0060558 regulation of calcidiol 1-monooxygenase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060558 Any process that modulates the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O. GO:0060559 positive regulation of calcidiol 1-monooxygenase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060559 Any process that increases the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is the catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O. GO:1901419 regulation of response to alcohol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901419 Any process that modulates the frequency, rate or extent of response to alcohol. GO:1901417 negative regulation of response to ethanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901417 down regulation of response to ethanol|downregulation of response to ethanol|down-regulation of response to ethanol|inhibition of response to ethanol Any process that stops, prevents or reduces the frequency, rate or extent of response to ethanol. GO:1901418 positive regulation of response to ethanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901418 upregulation of response to ethanol|up regulation of response to ethanol|activation of response to ethanol|up-regulation of response to ethanol Any process that activates or increases the frequency, rate or extent of response to ethanol. GO:1901415 positive regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901415 activation of tetrapyrrole synthesis from glycine and succinyl-CoA|activation of tetrapyrrole biosynthesis from glycine and succinyl-CoA|positive regulation of tetrapyrrole anabolism from glycine and succinyl-CoA|activation of tetrapyrrole formation from glycine and succinyl-CoA|up regulation of tetrapyrrole anabolism from glycine and succinyl-CoA|positive regulation of tetrapyrrole synthesis from glycine and succinyl-CoA|up-regulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA|up-regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA|up regulation of tetrapyrrole synthesis from glycine and succinyl-CoA|positive regulation of tetrapyrrole formation from glycine and succinyl-CoA|up regulation of tetrapyrrole formation from glycine and succinyl-CoA|upregulation of tetrapyrrole anabolism from glycine and succinyl-CoA|upregulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA|upregulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA|upregulation of tetrapyrrole synthesis from glycine and succinyl-CoA|upregulation of tetrapyrrole formation from glycine and succinyl-CoA|up-regulation of tetrapyrrole anabolism from glycine and succinyl-CoA|up regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA|up regulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA|up-regulation of tetrapyrrole synthesis from glycine and succinyl-CoA|activation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA|positive regulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA|activation of tetrapyrrole anabolism from glycine and succinyl-CoA|up-regulation of tetrapyrrole formation from glycine and succinyl-CoA Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process from glycine and succinyl-CoA. GO:1901416 regulation of response to ethanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901416 Any process that modulates the frequency, rate or extent of response to ethanol. GO:1901413 regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901413 regulation of tetrapyrrole anabolism from glycine and succinyl-CoA|regulation of tetrapyrrole synthesis from glycine and succinyl-CoA|regulation of tetrapyrrole formation from glycine and succinyl-CoA|regulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process from glycine and succinyl-CoA. GO:1901414 negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901414 down-regulation of tetrapyrrole synthesis from glycine and succinyl-CoA|negative regulation of tetrapyrrole synthesis from glycine and succinyl-CoA|down-regulation of tetrapyrrole formation from glycine and succinyl-CoA|negative regulation of tetrapyrrole formation from glycine and succinyl-CoA|inhibition of tetrapyrrole biosynthetic process from glycine and succinyl-CoA|downregulation of tetrapyrrole anabolism from glycine and succinyl-CoA|down regulation of tetrapyrrole anabolism from glycine and succinyl-CoA|downregulation of tetrapyrrole synthesis from glycine and succinyl-CoA|inhibition of tetrapyrrole biosynthesis from glycine and succinyl-CoA|downregulation of tetrapyrrole formation from glycine and succinyl-CoA|down regulation of tetrapyrrole synthesis from glycine and succinyl-CoA|down regulation of tetrapyrrole formation from glycine and succinyl-CoA|inhibition of tetrapyrrole anabolism from glycine and succinyl-CoA|down regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA|down regulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA|inhibition of tetrapyrrole synthesis from glycine and succinyl-CoA|downregulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA|downregulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA|inhibition of tetrapyrrole formation from glycine and succinyl-CoA|down-regulation of tetrapyrrole anabolism from glycine and succinyl-CoA|negative regulation of tetrapyrrole anabolism from glycine and succinyl-CoA|down-regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA|down-regulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA|negative regulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process from glycine and succinyl-CoA. GO:1901411 negative regulation of tetrapyrrole biosynthetic process from glutamate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901411 negative regulation of tetrapyrrole synthesis from glutamate|down-regulation of tetrapyrrole synthesis from glutamate|negative regulation of tetrapyrrole biosynthesis from glutamate|down-regulation of tetrapyrrole biosynthetic process from glutamate|down-regulation of tetrapyrrole biosynthesis from glutamate|negative regulation of tetrapyrrole anabolism from glutamate|down-regulation of tetrapyrrole anabolism from glutamate|inhibition of tetrapyrrole formation from glutamate|downregulation of tetrapyrrole biosynthetic process from glutamate|downregulation of tetrapyrrole biosynthesis from glutamate|inhibition of tetrapyrrole synthesis from glutamate|down regulation of tetrapyrrole biosynthesis from glutamate|down regulation of tetrapyrrole biosynthetic process from glutamate|inhibition of tetrapyrrole anabolism from glutamate|down regulation of tetrapyrrole formation from glutamate|inhibition of tetrapyrrole biosynthetic process from glutamate|down regulation of tetrapyrrole synthesis from glutamate|downregulation of tetrapyrrole formation from glutamate|inhibition of tetrapyrrole biosynthesis from glutamate|down regulation of tetrapyrrole anabolism from glutamate|downregulation of tetrapyrrole synthesis from glutamate|downregulation of tetrapyrrole anabolism from glutamate|negative regulation of tetrapyrrole formation from glutamate|down-regulation of tetrapyrrole formation from glutamate Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process from glutamate. GO:1901412 positive regulation of tetrapyrrole biosynthetic process from glutamate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901412 up regulation of tetrapyrrole anabolism from glutamate|activation of tetrapyrrole formation from glutamate|positive regulation of tetrapyrrole anabolism from glutamate|activation of tetrapyrrole biosynthesis from glutamate|activation of tetrapyrrole synthesis from glutamate|up-regulation of tetrapyrrole formation from glutamate|activation of tetrapyrrole anabolism from glutamate|positive regulation of tetrapyrrole biosynthesis from glutamate|up-regulation of tetrapyrrole synthesis from glutamate|up regulation of tetrapyrrole biosynthetic process from glutamate|up regulation of tetrapyrrole biosynthesis from glutamate|up-regulation of tetrapyrrole anabolism from glutamate|upregulation of tetrapyrrole formation from glutamate|upregulation of tetrapyrrole synthesis from glutamate|upregulation of tetrapyrrole biosynthesis from glutamate|upregulation of tetrapyrrole biosynthetic process from glutamate|upregulation of tetrapyrrole anabolism from glutamate|up regulation of tetrapyrrole formation from glutamate|positive regulation of tetrapyrrole formation from glutamate|up regulation of tetrapyrrole synthesis from glutamate|activation of tetrapyrrole biosynthetic process from glutamate|up-regulation of tetrapyrrole biosynthetic process from glutamate|up-regulation of tetrapyrrole biosynthesis from glutamate|positive regulation of tetrapyrrole synthesis from glutamate Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process from glutamate. GO:1901410 regulation of tetrapyrrole biosynthetic process from glutamate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901410 regulation of tetrapyrrole biosynthesis from glutamate|regulation of tetrapyrrole formation from glutamate|regulation of tetrapyrrole synthesis from glutamate|regulation of tetrapyrrole anabolism from glutamate Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process from glutamate. GO:0060540 diaphragm morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060540 The process in which the anatomical structures of the diaphragm are generated and organized. GO:0060541 respiratory system development biolink:BiologicalProcess go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0060541 The progression of the respiratory system over time from its formation to its mature structure. The respiratory system carries out respiratory gaseous exchange. GO:0060542 regulation of strand invasion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060542 Any process that modulates the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules. GO:0060543 negative regulation of strand invasion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060543 negative regulation of D-loop biosynthesis|negative regulation of D-loop formation|negative regulation of Rad51-mediated strand invasion Any process that decreases the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules. GO:0060544 regulation of necroptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060544 regulation of necroptosis Any process that modulates the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors. GO:0060545 positive regulation of necroptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060545 positive regulation of necroptosis Any process that increases the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors. GO:0060546 negative regulation of necroptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060546 negative regulation of necroptosis Any process that decreases the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors. GO:0060547 negative regulation of necrotic cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060547 Any process that decreases the rate, frequency or extent of necrotic cell death. Necrotic cell death is a cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents. GO:0060548 negative regulation of cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060548 Any process that decreases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death. GO:0060549 regulation of fructose 1,6-bisphosphate 1-phosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060549 Any process that modulates the rate, frequency or extent of fructose 1,6-bisphosphate 1-phosphatase activity. Fructose 1,6-bisphosphate 1-phosphatase activity is the catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. GO:1901428 regulation of syringal lignin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901428 regulation of syringal lignin biosynthesis|regulation of S-lignin biosynthetic process|regulation of syringal lignin anabolism|regulation of syringal lignin synthesis|regulation of syringal lignin formation Any process that modulates the frequency, rate or extent of syringal lignin biosynthetic process. GO:1901429 negative regulation of syringal lignin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901429 inhibition of S-lignin biosynthetic process|down-regulation of syringal lignin synthesis|negative regulation of syringal lignin synthesis|down-regulation of syringal lignin formation|negative regulation of syringal lignin formation|downregulation of syringal lignin biosynthetic process|downregulation of syringal lignin biosynthesis|down regulation of S-lignin biosynthetic process|inhibition of syringal lignin anabolism|down regulation of syringal lignin biosynthesis|down regulation of syringal lignin biosynthetic process|downregulation of S-lignin biosynthetic process|inhibition of syringal lignin biosynthetic process|inhibition of syringal lignin synthesis|down regulation of syringal lignin anabolism|inhibition of syringal lignin formation|inhibition of syringal lignin biosynthesis|downregulation of syringal lignin anabolism|down regulation of syringal lignin synthesis|down-regulation of S-lignin biosynthetic process|negative regulation of S-lignin biosynthetic process|down regulation of syringal lignin formation|downregulation of syringal lignin synthesis|downregulation of syringal lignin formation|down-regulation of syringal lignin anabolism|negative regulation of syringal lignin biosynthesis|negative regulation of syringal lignin anabolism|down-regulation of syringal lignin biosynthesis|down-regulation of syringal lignin biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of syringal lignin biosynthetic process. GO:1901426 response to furfural biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901426 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a furfural stimulus. GO:1901427 response to propan-1-ol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901427 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a propan-1-ol stimulus. GO:1901424 response to toluene biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901424 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toluene stimulus. GO:1901425 response to formic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901425 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a formic acid stimulus. GO:1901422 response to butan-1-ol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901422 process resulting in tolerance to butan-1-ol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butan-1-ol stimulus. GO:1901423 response to benzene biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901423 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzene stimulus. GO:1901420 negative regulation of response to alcohol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901420 down regulation of response to alcohol|downregulation of response to alcohol|down-regulation of response to alcohol|inhibition of response to alcohol Any process that stops, prevents or reduces the frequency, rate or extent of response to alcohol. GO:1901421 positive regulation of response to alcohol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901421 upregulation of response to alcohol|up regulation of response to alcohol|activation of response to alcohol|up-regulation of response to alcohol Any process that activates or increases the frequency, rate or extent of response to alcohol. GO:0060570 negative regulation of peptide hormone processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060570 Any process that decreases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone. GO:0060571 morphogenesis of an epithelial fold biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060571 folding of an epithelial sheet|epithelial folding The morphogenetic process in which an epithelial sheet bends along a linear axis. UBERON:0037447 wall of male urethra biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0037447 male urethral wall GO:0060572 morphogenesis of an epithelial bud biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060572 The morphogenetic process in which a bud forms from an epithelial sheet. A bud is a protrusion that forms form the sheet by localized folding. GO:0060573 cell fate specification involved in pattern specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060573 The process involved in the specification of the identity of a cell in a field of cells that is being instructed as to how to differentiate. Once specification has taken place, that cell will be committed to differentiate down a specific pathway if left in its normal environment. GO:0060574 intestinal epithelial cell maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060574 The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell of the intestine to attain its fully functional state. A columnar/cuboidal epithelial cell of the intestine mature as they migrate from the intestinal crypt to the villus. GO:0060575 intestinal epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060575 The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell of the intestine. GO:0060576 intestinal epithelial cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060576 The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell of the intestine over time, from its formation to the mature structure. GO:0060577 pulmonary vein morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060577 pulmonary venous blood vessel morphogenesis The process in which the anatomical structure of the pulmonary venous blood vessels are generated and organized. Pulmonary veins are blood vessels that transport blood from the lungs to the heart. GO:0060578 superior vena cava morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060578 The process in which the anatomical structure of superior vena cava generated and organized. The superior vena cava is a blood vessel that transports blood from the upper body to the heart. GO:0060579 ventral spinal cord interneuron fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060579 The process in which the developmental fate of a cell becomes restricted such that it will develop into a ventral spinal cord interneuron. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. GO:1901439 positive regulation of toluene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901439 upregulation of toluene metabolic process|up-regulation of methylbenzene metabolic process|positive regulation of toluene metabolism|upregulation of methylbenzene metabolism|up regulation of toluene metabolism|upregulation of methylbenzene metabolic process|up regulation of toluene metabolic process|activation of toluene metabolic process|up-regulation of methylbenzene metabolism|upregulation of toluene metabolism|activation of methylbenzene metabolism|up regulation of methylbenzene metabolic process|positive regulation of methylbenzene metabolic process|up-regulation of toluene metabolic process|up-regulation of toluene metabolism|positive regulation of methylbenzene metabolism|up regulation of methylbenzene metabolism|activation of methylbenzene metabolic process|activation of toluene metabolism Any process that activates or increases the frequency, rate or extent of toluene metabolic process. GO:1901437 regulation of toluene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901437 regulation of toluene metabolism|regulation of methylbenzene metabolic process|regulation of methylbenzene metabolism Any process that modulates the frequency, rate or extent of toluene metabolic process. GO:1901438 negative regulation of toluene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901438 down regulation of methylbenzene metabolism|down regulation of toluene metabolic process|inhibition of methylbenzene metabolic process|downregulation of toluene metabolic process|downregulation of toluene metabolism|inhibition of methylbenzene metabolism|down regulation of toluene metabolism|down regulation of methylbenzene metabolic process|down-regulation of toluene metabolic process|downregulation of methylbenzene metabolic process|inhibition of toluene metabolism|negative regulation of methylbenzene metabolism|down-regulation of methylbenzene metabolism|inhibition of toluene metabolic process|down-regulation of methylbenzene metabolic process|negative regulation of methylbenzene metabolic process|downregulation of methylbenzene metabolism|negative regulation of toluene metabolism|down-regulation of toluene metabolism Any process that stops, prevents or reduces the frequency, rate or extent of toluene metabolic process. GO:1901435 negative regulation of toluene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901435 downregulation of toluene catabolism|downregulation of toluene degradation|down regulation of toluene catabolism|down regulation of toluene breakdown|down regulation of toluene catabolic process|downregulation of toluene breakdown|inhibition of toluene catabolism|negative regulation of toluene degradation|downregulation of toluene catabolic process|down-regulation of toluene degradation|down-regulation of toluene breakdown|negative regulation of toluene breakdown|down-regulation of toluene catabolic process|negative regulation of toluene catabolism|down-regulation of toluene catabolism|inhibition of toluene degradation|inhibition of toluene catabolic process|inhibition of toluene breakdown|down regulation of toluene degradation Any process that stops, prevents or reduces the frequency, rate or extent of toluene catabolic process. UBERON:0037455 wall of female urethra biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0037455 female urethral wall GO:1901436 positive regulation of toluene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901436 upregulation of toluene breakdown|upregulation of toluene catabolic process|up regulation of toluene degradation|upregulation of toluene catabolism|positive regulation of toluene degradation|up regulation of toluene breakdown|activation of toluene degradation|positive regulation of toluene breakdown|up regulation of toluene catabolic process|up-regulation of toluene catabolism|activation of toluene catabolic process|activation of toluene breakdown|up-regulation of toluene degradation|activation of toluene catabolism|up-regulation of toluene breakdown|positive regulation of toluene catabolism|up-regulation of toluene catabolic process|upregulation of toluene degradation|up regulation of toluene catabolism Any process that activates or increases the frequency, rate or extent of toluene catabolic process. GO:1901433 positive regulation of response to cycloalkane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901433 up regulation of response to cycloalkane|activation of response to cycloalkane|up-regulation of response to cycloalkane|upregulation of response to cycloalkane Any process that activates or increases the frequency, rate or extent of response to cycloalkane. GO:1901434 regulation of toluene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901434 regulation of toluene degradation|regulation of toluene catabolism|regulation of toluene breakdown Any process that modulates the frequency, rate or extent of toluene catabolic process. GO:1901431 regulation of response to cycloalkane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901431 Any process that modulates the frequency, rate or extent of response to cycloalkane. GO:1901432 negative regulation of response to cycloalkane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901432 down-regulation of response to cycloalkane|inhibition of response to cycloalkane|down regulation of response to cycloalkane|downregulation of response to cycloalkane Any process that stops, prevents or reduces the frequency, rate or extent of response to cycloalkane. GO:0060560 developmental growth involved in morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060560 differential growth The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape. GO:1901430 positive regulation of syringal lignin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901430 activation of S-lignin biosynthetic process|up-regulation of syringal lignin biosynthesis|up-regulation of syringal lignin biosynthetic process|activation of syringal lignin biosynthetic process|up regulation of syringal lignin anabolism|positive regulation of syringal lignin anabolism|up-regulation of S-lignin biosynthetic process|up regulation of syringal lignin synthesis|activation of syringal lignin biosynthesis|positive regulation of syringal lignin synthesis|activation of syringal lignin anabolism|up regulation of syringal lignin formation|positive regulation of syringal lignin formation|positive regulation of syringal lignin biosynthesis|activation of syringal lignin synthesis|up regulation of syringal lignin biosynthesis|up regulation of syringal lignin biosynthetic process|upregulation of S-lignin biosynthetic process|up-regulation of syringal lignin anabolism|activation of syringal lignin formation|up-regulation of syringal lignin synthesis|up-regulation of syringal lignin formation|upregulation of syringal lignin biosynthesis|upregulation of syringal lignin biosynthetic process|upregulation of syringal lignin anabolism|up regulation of S-lignin biosynthetic process|positive regulation of S-lignin biosynthetic process|upregulation of syringal lignin synthesis|upregulation of syringal lignin formation Any process that activates or increases the frequency, rate or extent of syringal lignin biosynthetic process. GO:0060561 apoptotic process involved in morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060561 apoptosis involved in development|apoptosis involved in morphogenesis|morphogenetic apoptosis Any apoptotic process that contributes to the shaping of an anatomical structure. GO:0060562 epithelial tube morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060562 The process in which the anatomical structures of a tube are generated and organized from an epithelium. Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system. GO:0060563 neuroepithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060563 The process in which epiblast cells acquire specialized features of neuroepithelial cells. GO:0060564 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0060564 GO:0060565 obsolete inhibition of APC-Cdc20 complex activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060565 inhibition of cyclosome activity during mitotic cell cycle|inhibition of APC/C activity during mitotic cell cycle|inhibition of mitotic anaphase-promoting complex activity|inhibition of APC-Cdc20 complex activity|inhibition of APC activity during mitotic cell cycle OBSOLETE. Any process that prevents the activation of APC-Cdc20 complex activity regulating the mitotic cell cycle. GO:0060566 positive regulation of DNA-templated transcription, termination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060566 positive regulation of termination of DNA-dependent transcription|positive regulation of DNA-dependent transcription, termination|positive regulation of transcription termination, DNA-dependent Any process that increases the rate, frequency or extent of DNA-templated transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA. GO:0060567 negative regulation of DNA-templated transcription, termination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060567 negative regulation of termination of DNA-dependent transcription|negative regulation of DNA-dependent transcription, termination|negative regulation of transcription termination, DNA-dependent Any process that decreases the rate, frequency or extent of DNA-dependent transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA. GO:0060568 regulation of peptide hormone processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060568 Any process that modulates the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone. GO:0060569 positive regulation of peptide hormone processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060569 Any process that increases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone. UBERON:0003728 mediastinum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003728 mediastinal part of chest The central part of the thoracic cavity enclosed by the left and right pleurae. UBERON:0003729 mouth mucosa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003729 tunica mucosa oris|buccal mucosa|mucous membrane of mouth|mucosa of mouth|mouth mucosa|oral part of viscerocranial mucosa|mucosal lining of mouth|oral mucosa|oral mucous membrane|mouth organ mucosa|mouth mucous membrane|tunica mucosa oris A mucous membrane that lines the mouth. UBERON:0003726 thoracic nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003726 nervi thoracici|pectoral nerve|nervus thoracis|thoracic spinal nerve The twelve spinal nerves on each side of the thorax. They include eleven INTERCOSTAL NERVES and one subcostal nerve. Both sensory and motor, they supply the muscles and skin of the thoracic and abdominal walls. UBERON:0003727 intercostal nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003727 anterior ramus of thoracic nerve|ventral ramus of thoracic spinal nerve|nervi intercostales|ramus anterior, nervus thoracicus|anterior ramus of thoracic spinal nerve|thoracic anterior ramus The intercostal nerves are the anterior divisions (rami anteriores; ventral divisions) of the thoracic spinal nerves from T1 to T11. Each nerve is connected with the adjoining ganglion of the sympathetic trunk by a gray and a white ramus communicans. The intercostal nerves are distributed chiefly to the thoracic pleura and abdominal peritoneum and differ from the anterior divisions of the other spinal nerves in that each pursues an independent course without plexus formation. The first two nerves supply fibers to the upper limb in addition to their thoracic branches; the next four are limited in their distribution to the parietes of the thorax; the lower five supply the parietes of the thorax and abdomen. The 7th intercostal nerve terminates at the xyphoid process, at the lower end of the sternum. The 10th intercostal nerve terminates at the umbilicus. The twelfth thoracic is distributed to the abdominal wall and groin. [WP,unvetted]. UBERON:0003725 cervical nerve plexus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003725 cervical nerve plexus|plexus cervicalis|plexus cervicalis|cervical plexus An arrangement of nerve fibers, running from the spine that travels to the head and neck where it innervates skin and muscle. GO:0035702 monocyte homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035702 The process of regulating the proliferation and elimination of monocytes such that the total number of monocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus. GO:0035703 monocyte migration into blood stream biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035703 release of monocytes into circulation The movement of a monocyte from the bone marrow to the blood stream. GO:0035704 helper T cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035704 T-helper cell chemotaxis The directed movement of a helper T cell in response to an external stimulus. GO:0035705 T-helper 17 cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035705 Th17 cell chemotaxis The directed movement of a T-helper 17 cell in response to an external stimulus. GO:0035706 T-helper 1 cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035706 Th1 cell chemotaxis The directed movement of a T-helper 1 cell in response to an external stimulus. GO:0035707 T-helper 2 cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035707 Th2 cell chemotaxis The directed movement of a T-helper 2 cell in response to an external stimulus. GO:0035708 interleukin-4-dependent isotype switching to IgE isotypes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035708 IL-4-dependent isotype switching to IgE isotypes The switching of activated B cells from IgM biosynthesis to IgE biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgE constant region gene segments in the immunoglobulin heavy chain locus, that is dependent on the activity of interleukin 4 (IL-4). GO:0035709 memory T cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035709 The change in morphology and behavior of a memory T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. CHEBI:85521 1,2-dipalmitoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85521 CHEBI:61555 dUTP(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61555 CHEBI:61556 (KDO)2-(palmitoleoyl-myristoyl)-lipid A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61556 CHEBI:61553 D-fructofuranose 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61553 CHEBI:36586 carbonyl compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36586 CHEBI:85524 (3E,5Z,8Z,11Z,14Z)-icosapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85524 CHEBI:36587 organic oxo compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36587 CHEBI:61559 D-psicose 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61559 CHEBI:61557 nucleoside triphosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61557 CHEBI:85528 3-(methylthio)acryloyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85528 GO:0035700 astrocyte chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035700 The directed movement of an astrocyte guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). CHEBI:61558 (KDO)2-(palmitoleoyl)-lipid IVA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61558 GO:0035701 hematopoietic stem cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035701 hemopoietic stem cell migration The orderly movement of a hematopoietic stem cell from one site to another. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. CHEBI:85529 3-hydroxy-3-(methylthio)propanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85529 UBERON:0003715 splanchnic nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003715 visceral nerve|splanchnic nerves The major nerves supplying sympathetic innervation to the abdomen, including the greater, lesser, and lowest (or smallest) splanchnic nerves that are formed by preganglionic fibers from the spinal cord which pass through the paravertebral ganglia and then to the celiac ganglia and plexuses and the lumbar splanchnic nerves carry fibers which pass through the lumbar paravertebral ganglia to the mesenteric and hypogastric ganglia. UBERON:0003716 recurrent laryngeal nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003716 nervus laryngeus recurrens|recurrent nerve|vagus X nerve recurrent laryngeal branch|recurrent laryngeal nerve from vagus nerve|inferior laryngeal nerve|ramus recurrens A branch of the vagus nerve that supplies motor function and sensation to the larynx (voice box). It travels within the endoneurium. It is the nerve of the 6th Branchial Arch. UBERON:0003713 splenic vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003713 vena splenica|lienal vein|vena lienalis A vein arising from the splenic trabecular vein in the hilum of the spleen that drains into the portal vein. UBERON:0003714 neural tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003714 nerve tissue|portion of neural tissue|nervous tissue Portion of tissue in the nervous system which consists of neurons and glial cells, and may also contain parts of the vasculature. CHEBI:131602 CMP-8-amino-3,8-dideoxy-alpha-D-manno-oct-2-ulosonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131602 CHEBI:131603 sucrose 6(G)-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131603 CHEBI:131604 Mycoplasma genitalium metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131604 CHEBI:131605 dicarboxylic acid monoester(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131605 CHEBI:61562 dTDP-4-acetamido-4,6-dideoxy-D-galactose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61562 CHEBI:61563 farnesyl triphosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61563 CHEBI:61560 2'-deoxyribonucleoside 5'-triphosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61560 CHEBI:85510 7-hydroxylauric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85510 CHEBI:61561 beta-D-ManNAcA-(1->4)-alpha-D-GlcNAc-1-diphospho-ditrans,polycis-undecaprenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61561 CHEBI:61566 L-alanyl-D-glutamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61566 CHEBI:85511 6-(acylmethyl)-4-hydroxy-2H-pyran-2-one biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85511 CHEBI:61567 D-hexopyranose 6-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61567 CHEBI:61564 L-alanyl-gamma-D-glutamyl-meso-diaminopimelic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61564 CHEBI:85514 6-alkyl-4-hydroxy-2H-pyran-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85514 CHEBI:61565 L-alanyl-L-glutamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61565 CHEBI:85517 acarbose 7(IV)-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85517 UBERON:0003723 vestibular nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003723 nervus vestibularis|vestibulocochlear VIII nerve vestibular component|scarpa ganglion|vestibular root of eighth cranial nerve|scarpa's ganglion|scarpas ganglion|vestibular root of acoustic nerve|vestibulocochlear nerve vestibular root The vestibular nerve is one of the two branches of the Vestibulocochlear nerve (the cochlear nerve being the other). It goes to the semicircular canals via the vestibular ganglion. It receives positional information. Axons of the vestibular nerve synapse in the vestibular nucleus on the lateral floor and wall of the fourth ventricle in the pons and medulla. It arises from bipolar cells in the vestibular ganglion, ganglion of Scarpa, which is situated in the upper part of the outer end of the internal auditory meatus. [WP,unvetted]. UBERON:0003721 lingual nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003721 trigeminal nerve lingual branch|trigeminal V nerve lingual branch|lingual branch of trigeminal nerve The lingual nerve is a branch of the mandibular nerve (CN V3), itself a branch of the trigeminal nerve, which supplies sensory innervation to the tongue. It also carries fibers from the facial nerve, which return taste information from the anterior two thirds of the tongue. UBERON:0003709 circle of Willis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003709 arterial circle|cerebral arterial circle|arterial circle of Willis|Willis circle|circulus arteriosus cerebri A circle of arteries that supply blood to the brain. The Circle of Willis comprises the following arteries: Anterior cerebral artery (left and right); Anterior communicating artery; Internal carotid artery (left and right); Posterior cerebral artery (left and right); Posterior communicating artery (left and right).The basilar artery and middle cerebral arteries, supplying the brain, are also considered part of the circle UBERON:0003704 intrahepatic bile duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003704 bile duct intrahepatic part|intrahepatic biliary system Passages within the liver for the conveyance of bile. Includes right and left hepatic ducts even though these may join outside the liver to form the common hepatic duct. UBERON:0003703 extrahepatic bile duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003703 bile duct extrahepatic part|extrahepatic biliary system Passages external to the liver for the conveyance of bile. These include the common bile duct and the common hepatic duct. CHEBI:85541 elemental bismuth biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85541 CHEBI:61574 D-glycero-alpha-D-manno-heptose 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61574 CHEBI:85543 bismuth ion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85543 CHEBI:61572 digalactosylglycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61572 CHEBI:36564 N-benzoyl-4-methoxyanthranilate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36564 CHEBI:61575 alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61575 CHEBI:85547 9alpha-hydroxy-3-oxo-23,24-bisnorchola-1,4-dien-22-oyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85547 CHEBI:85548 9alpha-hydroxy-3-oxo-23,24-bisnorchol-4-en-22-oyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85548 CHEBI:85549 9alpha-hydroxyandrost-4-en-3,17-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85549 UBERON:0003711 brachiocephalic vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003711 innominate vein|brachiocephalic venous tree|innominate vein|innominate veins|innomiate vein|venae anonyma|vena brachiocephalica|innominate trunk The left and right brachiocephalic veins in the upper chest are formed by the union of each corresponding internal jugular vein and subclavian vein. This is at the level of the sternoclavicular joint. These great vessels merge to form the superior vena cava. The brachiocephalic veins are the major veins returning blood to the superior vena cava. CHEBI:36562 main-group coordination entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36562 CHEBI:85530 N(1),N(8)-bis(coumaroyl)spermidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85530 CHEBI:85531 trans-4-coumaroyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85531 CHEBI:85532 D-galactaro-1,4-lactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85532 CHEBI:85533 trans-4-hydroxy-L-proline betaine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85533 CHEBI:85534 cis-4-hydroxy-D-proline betaine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85534 CHEBI:61589 4-phospho-(KDO)-lipid IVA(7-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61589 CHEBI:61586 S-(hydroxymethyl)mycothiol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61586 CHEBI:36575 N-formylanthranilic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36575 CHEBI:85538 (R)-(2-chloro-5-oxo-2,5-dihydro-2-furyl)acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85538 CHEBI:36571 prenylglycerol phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36571 GO:1901806 beta-glucoside biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901806 beta-glucoside biosynthesis|beta-glucoside anabolism|beta-glucoside synthesis|beta-glucoside formation The chemical reactions and pathways resulting in the formation of beta-glucoside. GO:1901807 capsanthin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901807 capsanthin metabolism The chemical reactions and pathways involving capsanthin. GO:1901804 beta-glucoside metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901804 beta-glucoside metabolism The chemical reactions and pathways involving beta-glucoside. GO:1901805 beta-glucoside catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901805 beta-glucoside degradation|beta-glucoside catabolism|beta-glucoside breakdown The chemical reactions and pathways resulting in the breakdown of beta-glucoside. GO:1901802 1,5-anhydro-D-fructose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901802 1,5-anhydro-D-fructose degradation|1,5-anhydro-D-fructose breakdown|1,5-anhydro-D-fructose catabolism The chemical reactions and pathways resulting in the breakdown of 1,5-anhydro-D-fructose. GO:1901803 1,5-anhydro-D-fructose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901803 1,5-anhydro-D-fructose anabolism|1,5-anhydro-D-fructose synthesis|1,5-anhydro-D-fructose biosynthesis|1,5-anhydro-D-fructose formation The chemical reactions and pathways resulting in the formation of 1,5-anhydro-D-fructose. GO:1901800 positive regulation of proteasomal protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901800 up regulation of proteasome-mediated protein catabolic process|up-regulation of proteasome-mediated protein catabolism|upregulation of proteasomal protein catabolic process|positive regulation of proteasome-mediated protein catabolic process|activation of proteasome-mediated protein catabolism|activation of proteasome-mediated protein catabolic process|up regulation of proteasomal protein catabolic process|positive regulation of proteasome-mediated protein catabolism|up-regulation of proteasome-mediated protein catabolic process|up regulation of proteasome-mediated protein catabolism|activation of proteasomal protein catabolic process|upregulation of proteasome-mediated protein catabolic process|upregulation of proteasome-mediated protein catabolism|up-regulation of proteasomal protein catabolic process Any process that activates or increases the frequency, rate or extent of proteasomal protein catabolic process. GO:1901801 1,5-anhydro-D-fructose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901801 1,5-anhydro-D-fructose metabolism The chemical reactions and pathways involving 1,5-anhydro-D-fructose. CHEBI:85560 (5Z)-icosenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85560 CHEBI:61596 alpha-Neu5Ac-(2->3)-D-Gal biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61596 CHEBI:85563 lysophosphatidylcholine 6:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85563 CHEBI:85564 phosphatidylcholine 24:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85564 CHEBI:61593 D-glycero-beta-D-manno-heptose 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61593 CHEBI:61599 [8)-alpha-Neu5Ac-(2->]n biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61599 CHEBI:36544 sialodiosylceramide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36544 CHEBI:36542 sialopentaosylceramide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36542 CHEBI:36543 sialotetraosylceramide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36543 GO:0060710 chorio-allantoic fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060710 The cell-cell adhesion process in which the cells of the chorion fuse to the cells of the allantois. GO:0060711 labyrinthine layer development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060711 The process in which the labyrinthine layer of the placenta progresses, from its formation to its mature state. CHEBI:36546 sialomonoglycosylceramide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36546 GO:0060712 spongiotrophoblast layer development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060712 The process in which the spongiotrophoblast layer of the placenta progresses from its formation to its mature state. CHEBI:36547 pimarane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36547 GO:0060713 labyrinthine layer morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060713 The process in which the labyrinthine layer of the placenta is generated and organized. GO:0060714 labyrinthine layer formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060714 The developmental process pertaining to the initial formation of the labyrinthine layer of the placenta. GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060715 The process in which a chorionic trophoblast cell acquires specialized features of a syncytiotrophoblast of the labyrinthine layer of the placenta. GO:0060716 labyrinthine layer blood vessel development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060716 The process whose specific outcome is the progression of a blood vessel of the labyrinthine layer of the placenta over time, from its formation to the mature structure. The embryonic vessels grow through the layer to come in close contact with the maternal blood supply. GO:0060717 chorion development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060717 The biological process whose specific outcome is the progression of a chorion from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The chorion is an extraembryonic membrane. CHEBI:36540 ent-kaurane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36540 GO:0060718 chorionic trophoblast cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060718 The process in which relatively unspecialized cells of the ectoplacental cone acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer. CHEBI:36541 sialotriaosylceramide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36541 GO:0060719 chorionic trophoblast cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060719 The process whose specific outcome is the progression of the chorionic trophoblast over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. GO:1901808 capsanthin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901808 capsanthin degradation|capsanthin breakdown|capsanthin catabolism The chemical reactions and pathways resulting in the breakdown of capsanthin. GO:1901809 capsanthin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901809 capsanthin biosynthesis|capsanthin anabolism|capsanthin synthesis|capsanthin formation The chemical reactions and pathways resulting in the formation of capsanthin. GO:1901817 beta-zeacarotene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901817 beta-zeacarotene degradation|beta-zeacarotene breakdown|beta-zeacarotene catabolism The chemical reactions and pathways resulting in the breakdown of beta-zeacarotene. GO:1901818 beta-zeacarotene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901818 beta-zeacarotene anabolism|beta-zeacarotene synthesis|beta-zeacarotene biosynthesis|beta-zeacarotene formation The chemical reactions and pathways resulting in the formation of beta-zeacarotene. GO:1901815 astaxanthin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901815 astaxanthin anabolism|astaxanthin synthesis|astaxanthin formation|astaxanthin biosynthesis The chemical reactions and pathways resulting in the formation of astaxanthin. GO:1901816 beta-zeacarotene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901816 beta-zeacarotene metabolism The chemical reactions and pathways involving beta-zeacarotene. GO:1901813 astaxanthin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901813 astaxanthin metabolism The chemical reactions and pathways involving astaxanthin. GO:1901814 astaxanthin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901814 astaxanthin breakdown|astaxanthin catabolism|astaxanthin degradation The chemical reactions and pathways resulting in the breakdown of astaxanthin. GO:1901811 beta-carotene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901811 beta-carotene breakdown|beta-carotene catabolism|beta-carotene degradation The chemical reactions and pathways resulting in the breakdown of beta-carotene. GO:1901812 beta-carotene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901812 beta-carotene anabolism|beta-carotene synthesis|beta-carotene formation|beta-carotene biosynthesis The chemical reactions and pathways resulting in the formation of beta-carotene. GO:1901810 beta-carotene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901810 beta-carotene metabolism The chemical reactions and pathways involving beta-carotene. CHEBI:85550 9alpha-hydroxy-3-oxo-23,24-bisnorchol-4-en-22-oate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85550 CHEBI:85551 3-oxo-23,24-bisnorchola-1,4-dien-22-oate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85551 CHEBI:85552 15-dehydroprostaglandin A1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85552 CHEBI:85553 9alpha-hydroxy-3-oxo-23,24-bisnorchola-1,4-dien-22-oate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85553 CHEBI:85554 (2E,4E,8Z,11Z,14Z)-icosapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85554 CHEBI:36555 N-acetylanthranilic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36555 CHEBI:85555 (2E,4Z)-dienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85555 CHEBI:85556 trans,trans-2,4-dienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85556 CHEBI:85557 trans-3-cis-5-octadienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85557 CHEBI:36559 3-hydroxyanthranilate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36559 CHEBI:85559 (3E,5Z)-dienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85559 CHEBI:36557 N-methylanthranilate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36557 GO:0060700 regulation of ribonuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060700 Any process that modulates the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA. GO:0060701 negative regulation of ribonuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060701 Any process that decreases the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA. CHEBI:36558 3-hydroxy-4-methylanthranilate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36558 GO:0060702 negative regulation of endoribonuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060702 Any process that decreases the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks. GO:0060703 deoxyribonuclease inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0060703 DNase inhibitor activity Stops, prevents or reduces the activity of deoxyribonuclease. GO:0060704 acinar cell differentiation involved in salivary gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060704 The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize an acinar cell of the salivary gland. Acinar cells are protein-secreting cells in the gland. GO:0060705 neuron differentiation involved in salivary gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060705 The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the neurons of the salivary gland. GO:0060706 cell differentiation involved in embryonic placenta development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060706 The process in which a relatively unspecialized cell acquires specialized features of the embryonic placenta. GO:0060707 trophoblast giant cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060707 The process in which a relatively unspecialized cell acquires specialized features of a trophoblast giant cell of the placenta. Trophoblast giant cells are the cell of the placenta that line the maternal decidua. GO:0060708 spongiotrophoblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060708 spongiotrophoblast cell differentiation The process in which a relatively unspecialized cell of the ectoplacental cone acquires specialized features of a spongiotrophoblast of the placenta. A spongiotrophoblast cell is a basophilic cell. GO:1901819 alpha-zeacarotene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901819 alpha-zeacarotene metabolism The chemical reactions and pathways involving alpha-zeacarotene. GO:0060709 glycogen cell differentiation involved in embryonic placenta development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060709 The process in which a relatively unspecialized cell acquires specialized features of a glycogen cell of the placenta. A glycogen cell is a vacuolated glycogen-rich cell that appears in compact cell islets of the spongiotrophoblast layer. CHEBI:36550 sorbate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36550 GO:1901828 zeaxanthin bis(beta-D-glucoside) metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901828 zeaxanthin bis(beta-D-glucoside) metabolism|zeaxanthin diglucoside metabolism The chemical reactions and pathways involving zeaxanthin bis(beta-D-glucoside). GO:1901829 zeaxanthin bis(beta-D-glucoside) catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901829 zeaxanthin bis(beta-D-glucoside) degradation|zeaxanthin bis(beta-D-glucoside) breakdown|zeaxanthin bis(beta-D-glucoside) catabolism|zeaxanthin diglucoside degradation|zeaxanthin diglucoside catabolism|zeaxanthin diglucoside breakdown The chemical reactions and pathways resulting in the breakdown of zeaxanthin bis(beta-D-glucoside). GO:1901826 zeaxanthin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901826 zeaxanthin degradation|zeaxanthin breakdown|zeaxanthin catabolism The chemical reactions and pathways resulting in the breakdown of zeaxanthin. GO:1901827 zeaxanthin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901827 zeaxanthin biosynthesis|zeaxanthin anabolism|zeaxanthin synthesis|zeaxanthin formation The chemical reactions and pathways resulting in the formation of zeaxanthin. GO:1901824 delta-carotene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901824 delta-carotene anabolism|delta-carotene synthesis|delta-carotene formation|delta-carotene biosynthesis The chemical reactions and pathways resulting in the formation of delta-carotene. GO:1901825 zeaxanthin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901825 zeaxanthin metabolism The chemical reactions and pathways involving zeaxanthin. GO:1901822 delta-carotene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901822 delta-carotene metabolism The chemical reactions and pathways involving delta-carotene. GO:1901823 delta-carotene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901823 delta-carotene degradation|delta-carotene breakdown|delta-carotene catabolism The chemical reactions and pathways resulting in the breakdown of delta-carotene. GO:1901820 alpha-zeacarotene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901820 alpha-zeacarotene breakdown|alpha-zeacarotene catabolism|alpha-zeacarotene degradation The chemical reactions and pathways resulting in the breakdown of alpha-zeacarotene. GO:1901821 alpha-zeacarotene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901821 alpha-zeacarotene anabolism|alpha-zeacarotene biosynthesis|alpha-zeacarotene synthesis|alpha-zeacarotene formation The chemical reactions and pathways resulting in the formation of alpha-zeacarotene. CHEBI:36528 alpha-Neup5NAc-(2->3)-beta-D-Galp-(1->4)-beta-D-GlcpNAc-(1->3)-beta-D-Galp-(1->4)-beta-D-Glcp-(1<->1')-Cer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36528 CHEBI:36529 aristolochene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36529 CHEBI:85586 glutathione S-sulfinate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85586 CHEBI:85587 9-hydroperoxy-10E-octadecenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85587 CHEBI:36522 eudesmane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36522 CHEBI:36523 humulane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36523 CHEBI:85589 10-hydroperoxy-8E-octadecenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85589 CHEBI:36520 oligoglycosylceramide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36520 GO:0060730 regulation of intestinal epithelial structure maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060730 Any process that modulates the rate, frequency, or extent of intestinal epithelial structure maintenance, a tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium. CHEBI:36521 eremophilane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36521 GO:0060731 positive regulation of intestinal epithelial structure maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060731 Any process the increases the rate, frequency or extent of intestinal epithelial structure maintenance, a tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium. CHEBI:36526 acidic glycosphingolipid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36526 GO:0060732 positive regulation of inositol phosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060732 Any process that increases the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached. CHEBI:36527 glycosylsphingoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36527 GO:0060733 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0060733 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060734 regulation of eIF2 alpha phosphorylation by ER stress|regulation of eIF2 alpha phosphorylation by endoplasmic reticulum stress|regulation of ER stress-induced eIF2 alpha phosphorylation Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to endoplasmic reticulum stress. GO:0060735 regulation of eIF2 alpha phosphorylation by dsRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060735 regulation of eIF2 alpha phosphorylation by double-stranded RNA|regulation of eIF2 alpha phosphorylation by PKR Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to double-stranded RNA. GO:0060736 prostate gland growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060736 The increase in size or mass of the prostate gland where the increase in size or mass has the specific outcome of the progression of the gland, from its formation to its mature state. GO:0060737 prostate gland morphogenetic growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060737 prostate gland growth involved in morphogenesis The differential increase in size or mass of the prostate gland that contributes to the gland attaining its form. GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060738 epithelial-mesenchymal signalling involved in prostate gland development Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted and contributes to the progression of the prostate gland over time. GO:0060739 mesenchymal-epithelial cell signaling involved in prostate gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060739 mesenchymal-epithelial cell signalling involved in prostate gland development Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted contributing to the progression of the prostate gland over time. GO:1901839 regulation of RNA polymerase I regulatory region sequence-specific DNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901839 Any process that modulates the frequency, rate or extent of RNA polymerase I regulatory region sequence-specific DNA binding. GO:1901837 negative regulation of transcription of nucleolar large rRNA by RNA polymerase I biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|down-regulation of transcription of nuclear rRNA large Pol I transcript|negative regulation of transcription of nuclear rRNA large Pol I transcript|down regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|downregulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|downregulation of transcription of nuclear rRNA large Pol I transcript|down regulation of transcription of nuclear rRNA large Pol I transcript|down-regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|inhibition of transcription of nuclear rRNA large Pol I transcript|inhibition of transcription of nuclear large rRNA transcript from RNA polymerase I promoter Any process that stops, prevents or reduces the frequency, rate or extent of transcription of nuclear large rRNA transcript mediated by RNA polymerase I. GO:1901838 positive regulation of transcription of nucleolar large rRNA by RNA polymerase I biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|upregulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|activation of transcription of nuclear rRNA large Pol I transcript|positive regulation of transcription of nuclear rRNA large Pol I transcript|up regulation of transcription of nuclear rRNA large Pol I transcript|up regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|activation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|upregulation of transcription of nuclear rRNA large Pol I transcript|up-regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|up-regulation of transcription of nuclear rRNA large Pol I transcript Any process that activates or increases the frequency, rate or extent of transcription of nuclear large rRNA mediated by RNA polymerase I. GO:1901835 positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901835 activation of deadenylation-independent decapping of nuclear mRNA|up regulation of deadenylylation-independent decapping|up-regulation of deadenylation-independent decapping of nuclear-transcribed mRNA|positive regulation of deadenylylation-independent decapping|up-regulation of deadenylation-independent decapping of nuclear mRNA|activation of deadenylylation-independent decapping|upregulation of deadenylation-independent decapping of nuclear-transcribed mRNA|upregulation of deadenylation-independent decapping of nuclear mRNA|up-regulation of deadenylylation-independent decapping|up regulation of deadenylation-independent decapping of nuclear-transcribed mRNA|activation of deadenylation-independent decapping of nuclear-transcribed mRNA|upregulation of deadenylylation-independent decapping|up regulation of deadenylation-independent decapping of nuclear mRNA|positive regulation of deadenylation-independent decapping of nuclear mRNA Any process that activates or increases the frequency, rate or extent of deadenylation-independent decapping of nuclear-transcribed mRNA. GO:1901836 regulation of transcription of nucleolar large rRNA by RNA polymerase I biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901836 regulation of transcription of nuclear rRNA large Pol I transcript|regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter Any process that modulates the frequency, rate or extent of transcription of nuclear large rRNA mediated by RNA polymerase I. GO:1901833 all-trans-neoxanthin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901833 neoxanthin synthesis|neoxanthin formation|all-trans-neoxanthin biosynthesis|all-trans-neoxanthin anabolism|all-trans-neoxanthin synthesis|all-trans-neoxanthin formation|neoxanthin biosynthetic process|neoxanthin biosynthesis|neoxanthin anabolism The chemical reactions and pathways resulting in the formation of all-trans-neoxanthin. GO:1901834 regulation of deadenylation-independent decapping of nuclear-transcribed mRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901834 regulation of deadenylylation-independent decapping|regulation of deadenylation-independent decapping of nuclear mRNA Any process that modulates the frequency, rate or extent of deadenylation-independent decapping of nuclear-transcribed mRNA. GO:1901831 all-trans-neoxanthin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901831 all-trans-neoxanthin metabolism|neoxanthin metabolic process|neoxanthin metabolism The chemical reactions and pathways involving all-trans-neoxanthin. GO:0045105 intermediate filament polymerization or depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045105 Assembly or disassembly of intermediate filaments by the addition or removal of component parts from a filament. GO:1901832 all-trans-neoxanthin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901832 all-trans-neoxanthin degradation|all-trans-neoxanthin catabolism|all-trans-neoxanthin breakdown|neoxanthin degradation|neoxanthin catabolism|neoxanthin breakdown|neoxanthin catabolic process The chemical reactions and pathways resulting in the breakdown of all-trans-neoxanthin. GO:0045106 intermediate filament depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045106 Disassembly of intermediate filaments by the removal of component monomers from a filament. CHEBI:36539 kaurane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36539 GO:0045103 intermediate filament-based process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045103 Any cellular process that depends upon or alters the intermediate filament cytoskeleton, that part of the cytoskeleton comprising intermediate filaments and their associated proteins. GO:0045104 intermediate filament cytoskeleton organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045104 intermediate filament cytoskeleton organisation|intermediate filament cytoskeleton organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising intermediate filaments and their associated proteins. GO:1901830 zeaxanthin bis(beta-D-glucoside) biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901830 zeaxanthin bis(beta-D-glucoside) synthesis|zeaxanthin bis(beta-D-glucoside) formation|zeaxanthin diglucoside biosynthesis|zeaxanthin diglucoside anabolism|zeaxanthin diglucoside synthesis|zeaxanthin diglucoside formation|zeaxanthin bis(beta-D-glucoside) biosynthesis|zeaxanthin bis(beta-D-glucoside) anabolism The chemical reactions and pathways resulting in the formation of zeaxanthin bis(beta-D-glucoside). GO:0045101 obsolete glial fibrillary acidic protein biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045101 glial fibrillary acidic protein|GFAP OBSOLETE. Glial fibrillary acidic protein forms filaments in the glial cells that surround neurons and in astrocytes. GO:0045102 obsolete peripherin biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045102 peripherin OBSOLETE. Peripherin is a type III intermediate filament protein found in neurons of the peripheral nervous system. CHEBI:85575 3,17-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85575 GO:0045100 obsolete desmin biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045100 desmin OBSOLETE. A type of intermediate filament. CHEBI:85576 3,4,17-trihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85576 CHEBI:36534 2,6,10-trimethyldodeca-2,6,10-triene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36534 CHEBI:36531 (2Z,4E)-5-carboxy-2,3,5-trichloropenta-2,4-dienoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36531 GO:0060720 spongiotrophoblast cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060720 The multiplication or reproduction of spongiotrophoblast cells, resulting in the expansion of the population in the spongiotrophoblast layer. GO:0045109 intermediate filament organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045109 intermediate filament organisation Control of the spatial distribution of intermediate filaments; includes organizing filaments into meshworks, bundles, or other structures, as by cross-linking. CHEBI:36538 2-hydroxy-6-(2-hydroxyphenyl)-6-oxo-cis,cis-hexa-2,4-dienoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36538 GO:0060721 regulation of spongiotrophoblast cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060721 Any process that modulates the rate, frequency or extent of spongiotrophoblast cell proliferation. GO:0060722 cell proliferation involved in embryonic placenta development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060722 The multiplication or reproduction of cells, resulting in the expansion of the population in the embryonic placenta. GO:0045107 intermediate filament polymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045107 Assembly of intermediate filaments by the addition of component monomers to a filament. Polymerization of intermediate filament proteins results from interactions among several distinct binding sites on the constituent proteins. Nuclear lamin head-to-tail polymers arise from one such interaction. Deletion analysis localized the binding sites to the ends of the rod domain that are highly conserved among all intermediate filament proteins. Data indicate that one type of interaction in intermediate filament protein polymerization is the longitudinal binding of dimers via the conserved end segments of the coiled-coil rod domain. GO:0045108 regulation of intermediate filament polymerization or depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045108 Any process that modulates the frequency, rate or extent of the assembly or disassembly of intermediate filaments by the addition or removal of monomers from a filament; this usually occurs through the opposing action of kinases and phosphatases. GO:0060723 regulation of cell proliferation involved in embryonic placenta development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060723 Any process that modulates the rate, frequency, or extent of cell proliferation involved in embryonic placenta development. GO:0060724 coreceptor activity involved in epidermal growth factor receptor signaling pathway biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0060724 coreceptor activity involved in epidermal growth factor receptor signalling pathway Combining with an extracellular messenger, and in cooperation with a primary EGF receptor, initiating a change in cell activity through the EGF receptor signaling pathway. GO:0060725 regulation of coreceptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060725 Any process that modulates the rate or frequency of coreceptor activity, combining with an extracellular or intracellular messenger, and in cooperation with a nearby primary receptor, initiating a change in cell activity. GO:0060726 regulation of coreceptor activity involved in epidermal growth factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060726 regulation of Neu/ErbB-2 receptor activity|regulation of coreceptor activity involved in epidermal growth factor receptor signalling pathway Any process that modulates the rate or frequency of coreceptor activity involved in epidermal growth factor receptor signaling pathway. GO:0060727 positive regulation of coreceptor activity involved in epidermal growth factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060727 positive regulation of coreceptor activity involved in epidermal growth factor receptor signalling pathway|positive regulation of Neu/ErbB-2 receptor activity Any process that increases the rate or frequency of coreceptor activity involved in epidermal growth factor receptor signaling pathway. GO:0060728 negative regulation of coreceptor activity involved in epidermal growth factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060728 negative regulation of coreceptor activity involved in epidermal growth factor receptor signalling pathway|negative regulation of Neu/ErbB-2 receptor activity Any process that decreases the rate or frequency of coreceptor activity involved in epidermal growth factor receptor signaling pathway. GO:0060729 intestinal epithelial structure maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060729 maintenance of intestinal epithelium|epithelial structure maintenance of intestine A tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium. CHEBI:36530 cedrane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36530 CHEBI:141005 (6S)-5,6,7,8-tetrahydrofolyl-poly(gamma-glutamate) macromolecule biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_141005 PATO:0001979 lobed biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PATO_0001979 A shape quality inhering in a bearer by virtue of the bearer's being partly divided into a determinate number of regions. GO:0035782 mature natural killer cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035782 activated natural killer cell chemotaxis The directed movement of a mature natural killer cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). A mature natural killer cell is a natural killer cell that is developmentally mature and expresses a variety of inhibitory and activating receptors that recognize MHC class and other stress related molecules. GO:0035783 CD4-positive, alpha-beta T cell costimulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035783 CD4-positive, alpha beta T cell costimulation The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment CD4-positive, alpha-beta T cell activation. GO:0035784 nickel cation homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035784 nickel homeostasis Any process involved in the maintenance of an internal steady state of nickel cations within an organism or cell. GO:0035785 cellular nickel ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035785 cellular nickel homeostasis Any process involved in the maintenance of an internal steady state of nickel ions at the level of a cell. GO:0035786 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035786 GO:0035787 cell migration involved in kidney development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035787 The orderly movement of a cell from one site to another that will contribute to the progression of the kidney over time, from its formation to the mature organ. GO:0035788 cell migration involved in metanephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035788 cell migration involved in metanephric kidney development The orderly movement of a cell from one site to another that will contribute to the progression of the metanephric kidney over time, from its formation to the mature organ. GO:0035789 metanephric mesenchymal cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035789 metanephric mesenchyme chemotaxis The orderly movement of undifferentiated metanephric mesenchymal cells (precursors to metanephric mesangial cells) from the mesenchyme into the cleft of the developing glomerulus, during development of the metanephros. GO:0035780 CD80 biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035780 CD80 biosynthesis|CD80 anabolism|CD80 synthesis|CD80 formation The chemical reactions and pathways resulting in the formation of CD80, a CD marker that occurs on antigen presenting cells such as activated B cells and monocytes that provides a co-stimulatory signal necessary for T cell activation and survival. GO:0035781 CD86 biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035781 CD86 anabolism|CD86 synthesis|CD86 formation|CD86 biosynthesis The chemical reactions and pathways resulting in the formation of CD86, a CD marker that occurs on antigen presenting cells that provides co-stimulatory signals necessary for T cell activation and survival. GO:0035779 angioblast cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035779 angioblastic mesenchymal cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an angioblast cell. Angioblasts are one of the two products formed from hemangioblast cells (the other being pluripotent hemopoietic stem cells). GO:0035771 interleukin-4-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035771 interleukin-4-mediated signalling pathway|IL-4-mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-4 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0035772 interleukin-13-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035772 interleukin-13-mediated signalling pathway|IL-13-mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-13 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0035773 insulin secretion involved in cellular response to glucose stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035773 insulin secretion involved in cellular response to glucose The regulated release of proinsulin from secretory granules (B granules) in the B cells of the pancreas; accompanied by cleavage of proinsulin to form mature insulin, in response to a glucose stimulus. GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035774 positive regulation of insulin secretion in response to glucose Any process that increases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose. GO:0035775 pronephric glomerulus morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035775 The process in which the anatomical structures of the pronephric glomerulus are generated and organized. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment. GO:0035776 pronephric proximal tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035776 The progression of the pronephric proximal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros. GO:0035777 pronephric distal tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035777 The process whose specific outcome is the progression of the pronephric distal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros. GO:0035778 pronephric nephron tubule epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035778 The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephric nephron tubule as it progresses from its formation to the mature state. GO:0035770 ribonucleoprotein granule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035770 mRNP granule|RNP granule|RNA granule A non-membranous macromolecular complex containing proteins and translationally silenced mRNAs. RNA granules contain proteins that control the localization, stability, and translation of their RNA cargo. Different types of RNA granules (RGs) exist, depending on the cell type and cellular conditions. GO:0035768 endothelial cell chemotaxis to fibroblast growth factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035768 The directed movement of an endothelial cell in response to the presence of fibroblast growth factor (FGF). GO:0035769 B cell chemotaxis across high endothelial venule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035769 B-cell chemotaxis across high endothelial venule The movement of a B cell to cross a high endothelial venule in response to an external stimulus. CHEBI:131657 cholane derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131657 GO:0035760 cytoplasmic polyadenylation-dependent rRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035760 cytoplasmic poly(A)-dependent rRNA catabolic process The chemical reactions and pathways occurring in the cytoplasm and resulting in the breakdown of a ribosomal RNA (rRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA truncated degradation intermediate. GO:0035761 dorsal motor nucleus of vagus nerve maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035761 A developmental process, independent of morphogenetic (shape) change, that is required for the dorsal motor nucleus of the vagus nerve to attain its fully functional state. GO:0035762 dorsal motor nucleus of vagus nerve morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035762 The process in which the dorsal motor nucleus of the vagus nerve is generated and organized. Morphogenesis pertains to the creation of form. CHEBI:131650 phosphinomethylisomalate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131650 GO:0035763 dorsal motor nucleus of vagus nerve structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035763 dorsal motor nucleus of vagus nerve structural organisation The process that contributes to the act of creating the structural organization of the dorsal motor nucleus of the vagus nerve. This process pertains to the physical shaping of a rudimentary structure. CHEBI:131651 2-(phosphinatomethylidene)succinate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131651 GO:0035764 dorsal motor nucleus of vagus nerve formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035764 The process that gives rise to the dorsal motor nucleus of the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts. CHEBI:131652 cholestanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131652 GO:0035765 motor neuron precursor migration involved in dorsal motor nucleus of vagus nerve formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035765 The orderly movement of a motor neuron precursor cell that contributes to formation of the dorsal motor nucleus of the vagus nerve. GO:0035766 cell chemotaxis to fibroblast growth factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035766 The directed movement of a motile cell in response to the presence of fibroblast growth factor (FGF). GO:0035767 endothelial cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035767 The directed movement of an endothelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). GO:0035757 chemokine (C-C motif) ligand 19 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035757 CCL19 binding Interacting selectively and non-covalently with chemokine (C-C motif) ligand 19. GO:0035758 chemokine (C-C motif) ligand 21 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035758 CCL21 binding Interacting selectively and non-covalently with chemokine (C-C motif) ligand 21. GO:0035759 mesangial cell-matrix adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035759 The binding of a mesangial cell to the extracellular matrix via adhesion molecules. A mesangial cell is a cell that encapsulates the capillaries and venules in the kidney. GO:0035750 protein localization to myelin sheath abaxonal region biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035750 protein localisation to myelin sheath abaxonal region Any process in which a protein is transported to, and/or maintained in, the abaxonal region of the myelin sheath. The abaxonal region is the region of the myelin sheath furthest from the axon. GO:0035751 regulation of lysosomal lumen pH biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035751 Any process that modulates the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion. GO:0035752 lysosomal lumen pH elevation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035752 lysosome pH elevation Any process that increases the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion. GO:0035753 maintenance of DNA trinucleotide repeats biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035753 Any process involved in sustaining the fidelity and copy number of DNA trinucleotide repeats. DNA trinucleotide repeats are naturally occurring runs of three base-pairs. CHEBI:61505 cyanidin 3-O-(2-O-beta-D-glucuronosyl)-beta-D-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61505 GO:0035754 B cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035754 The directed movement of a B cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). GO:0035755 cardiolipin hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035755 Reactome:R-HSA-8954398 Catalysis of the hydrolysis of cardiolipin (1,3-bis(3-phosphatidyl)glycerol) to form phosphatidic acid (PA). CHEBI:61502 heptosyl-(KDO)2-lipid A(6-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61502 GO:0035756 transepithelial migration of symbiont in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035756 migration of symbiont within host by transepithelial trafficking|migration in host through an epithelial cell layer|transmigration of symbiont in host The directional movement of an organism from one side of an epithelium to the other within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:61508 gamma-glutamyl-gamma-aminobutyraldehyde zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61508 CHEBI:61509 N-acetyl-L-2-aminoadipate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61509 CHEBI:61506 ADP-L-glycero-beta-D-manno-heptose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61506 CHEBI:61507 (heptosyl)2-(KDO)2-lipid A(6-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61507 GO:0035746 granzyme A production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0035746 The appearance of granzyme A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. CHEBI:131634 pregnane derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131634 GO:0035747 natural killer cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035747 The directed movement of a natural killer cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). CHEBI:131635 estrane derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131635 GO:0035748 myelin sheath abaxonal region biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035748 The region of the myelin sheath furthest from the axon. CHEBI:131636 GDP-4-amino-3,4,6-trideoxy-alpha-D-threo-hex-3-enopyranose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131636 GO:0035749 myelin sheath adaxonal region biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035749 The region of the myelin sheath nearest to the axon. CHEBI:131639 GDP-(2S,3S,6R)-3-hydroxy-5-imino-6-methyloxane(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131639 CHEBI:61511 N-acetyl-L-2-aminoadipate semialdehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61511 CHEBI:61512 N(2)-acetyl-L-lysine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61512 GO:0035740 CD8-positive, alpha-beta T cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035740 The expansion of a CD8-positive, alpha-beta T cell population by cell division. CHEBI:61510 N-acetyl-L-2-aminoadipate 6-phosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61510 GO:0035741 activated CD4-positive, alpha-beta T cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035741 The expansion of an activated CD4-positive, alpha-beta T cell population by cell division. GO:0035742 activated CD8-positive, alpha-beta T cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035742 The expansion of an activated CD8-positive, alpha-beta T cell population by cell division. CHEBI:61515 N-acetyl-L-2-aminoadipic acid semialdehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61515 GO:0035743 CD4-positive, alpha-beta T cell cytokine production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0035743 Any process that contributes to cytokine production by a CD4-positive, alpha-beta T cell. GO:0035744 T-helper 1 cell cytokine production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0035744 Th1 cell cytokine production Any process that contributes to cytokine production by a T-helper 1 cell. CHEBI:61513 gamma-butyrobetainyl-CoA(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61513 CHEBI:131632 lanostane derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131632 GO:0035745 T-helper 2 cell cytokine production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0035745 Th2 cell cytokine production Any process that contributes to cytokine production by a T-helper 2 cell. CHEBI:61519 D-psicose 6-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61519 CHEBI:61517 gamma-butyrobetainyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61517 GO:0035735 intraciliary transport involved in cilium assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035735 Reactome:R-HSA-5620924.2 intraflagellar transport involved in cilium morphogenesis|intraflagellar transport|intraciliary transport involved in cilium morphogenesis The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly. GO:0035736 cell proliferation involved in compound eye morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035736 The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to compound eye morphogenesis. CHEBI:131647 androstane sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131647 GO:0035737 injection of substance in to other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035737 The process of forcing a substance into another organism, either by penetrating the skin of the other organism or by applying the substance externally to a sensitive tissue such as those that surround the eyes. GO:0035738 envenomation resulting in modulation of process in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035738 envenomation resulting in modification of morphology or physiology of other organism The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with the manifestation of some change or damage to the bitten organism. GO:0035739 CD4-positive, alpha-beta T cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035739 The expansion of a CD4-positive, alpha-beta T cell population by cell division. CHEBI:61522 (KDO)2-(palmitoleoyl-myristoyl)-lipid A(6-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61522 CHEBI:61523 (heptosyl)2-(KDO)2-lipid A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61523 CHEBI:61520 (KDO)2-(palmitoleoyl)-lipid IVA(6-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61520 CHEBI:61521 gamma-glutamyl-gamma-aminobutyraldehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61521 GO:0035730 S-nitrosoglutathione binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035730 GSNO binding Interacting selectively and non-covalently with S-nitrosoglutathione, a nitrosothiol considered to be a natural nitric oxide (NO) donor involved in S-nitrosylation, and in the storage and transport of nitric oxide in biological systems. GO:0035731 dinitrosyl-iron complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035731 DNIC binding|DNDGIC binding|dinitrosyl-diglutathionyl-iron complex binding Interacting selectively and non-covalently with a dinitrosyl-iron complex. Nitric oxide (NO) is stored as dinitrosyl-iron complexes, which form spontaneously from Glutathione (GSH), S-nitrosoglutathione, and trace amounts of ferrous ions, or by reaction of iron-sulfur centers with NO. CHEBI:61526 (E)-hexadec-2-enoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61526 GO:0035732 nitric oxide storage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035732 NO storage The accumulation and maintenance in cells or tissues of nitric oxide (NO). Nitric oxide is stored in the form of dinitrosyl-iron complexes, which are stabilized, and possibly sequestered, by binding to glutathione S-transferase proteins. CHEBI:61527 D-fructofuranose 6-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61527 GO:0035733 hepatic stellate cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035733 A change in the morphology or behavior of a hepatic stellate cell resulting from exposure to a cytokine, chemokine, hormone, cellular ligand or soluble factor. CHEBI:61524 (KDO)2-(lauroyl)-lipid IVA(6-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61524 GO:0035734 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035734 CHEBI:61528 heptosyl-(KDO)2-lipid A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61528 CHEBI:61529 alpha-L-Fucp-(1->2)-beta-D-Galp biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61529 GO:0035724 CD24 biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035724 CD24 biosynthesis|CD24 anabolism|CD24 synthesis|CD24 formation The chemical reactions and pathways resulting in the formation of CD24, a CD marker and cell adhesion molecule that occurs on many B-lineage cells and mature granulocytes, and is involved in B cell activation and differentiation as well as T cell co-stimulation. GO:0035725 sodium ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035725 sodium ion membrane transport A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. GO:0035726 common myeloid progenitor cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035726 The multiplication or reproduction of common myeloid progenitor cells, resulting in the expansion of a cell population. A common myeloid progenitor cell is a progenitor cell committed to the myeloid lineage. GO:0035727 lysophosphatidic acid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035727 LPA binding Interacting selectively and non-covalently with lysophosphatidic acid (LPA), a phospholipid derivative that acts as a potent mitogen due to its activation of high-affinity G protein-coupled receptors. GO:0035728 response to hepatocyte growth factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035728 response to HGF stimulus|response to hepatocyte growth factor stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hepatocyte growth factor stimulus. GO:0035729 cellular response to hepatocyte growth factor stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035729 cellular response to HGF stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hepatocyte growth factor stimulus. CHEBI:131617 18-oxoresolvin E1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131617 CHEBI:61530 ADP-L-glycero-beta-D-manno-heptose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61530 CHEBI:131619 C27-steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131619 CHEBI:61533 alpha-D-FucNAc4-(1->4)-beta-D-ManNAcA-(1->4)-D-GlcNAc-undecaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61533 CHEBI:85501 N(4)-(beta-D-glucosyl)-L-asparagine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85501 GO:0035720 intraciliary anterograde transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035720 intraflagellar anterograde transport The directed movement of large protein complexes along microtubules from the cell body toward the tip of a cilium (also called flagellum), mediated by motor proteins. CHEBI:85504 2,6-dimethylheptanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85504 CHEBI:61537 UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-N-acetyl-alpha-glucosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61537 GO:0035721 intraciliary retrograde transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035721 intraflagellar retrograde transport The directed movement of large protein complexes along microtubules from the tip of a cilium (also called flagellum) toward the cell body, mediated by motor proteins. GO:0035722 interleukin-12-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035722 IL-12-mediated signaling pathway|interleukin-12-mediated signalling pathway A series of molecular signals initiated by the binding of interleukin-12 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. CHEBI:131610 O-(beta-L-arabinofuranosyl)-trans-4-hydroxy-L-proline residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131610 GO:0035723 interleukin-15-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035723 IL-15-mediated signaling pathway|interleukin-15-mediated signalling pathway A series of molecular signals initiated by the binding of interleukin-15 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. CHEBI:85507 GDP-alpha-D-mannuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85507 CHEBI:85508 (9Z,12Z)-18-hydroxyoctadecadienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85508 CHEBI:85509 3-amino-N-(trans-3-carbamoyloxirane-2-carbonyl)-L-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85509 GO:0035713 response to nitrogen dioxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035713 response to NO2 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen dioxide (NO2) stimulus. GO:0035714 cellular response to nitrogen dioxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035714 cellular response to NO2 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen dioxide (NO2) stimulus. GO:0035715 chemokine (C-C motif) ligand 2 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035715 CCL2 binding Interacting selectively and non-covalently with chemokine (C-C motif) ligand 2. GO:0035716 chemokine (C-C motif) ligand 12 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035716 CCL12 binding Interacting selectively and non-covalently with chemokine (C-C motif) ligand 12. CHEBI:61540 palmitoleoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61540 GO:0035717 chemokine (C-C motif) ligand 7 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035717 CCL7 binding Interacting selectively and non-covalently with chemokine (C-C motif) ligand 7. GO:0035718 macrophage migration inhibitory factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035718 MIF binding Interacting selectively and non-covalently with the cytokine, macrophage migration inhibitory factor. GO:0035719 tRNA import into nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035719 retrograde tRNA transport into nucleus|tRNA nuclear import The directed movement of tRNA from the cytoplasm to the nucleus. CHEBI:61543 undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61543 CHEBI:61548 D-glucopyranose 6-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61548 GO:0035710 CD4-positive, alpha-beta T cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035710 The change in morphology and behavior of a CD4-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. CHEBI:131620 C24-steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131620 GO:0035711 T-helper 1 cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035711 Th1 cell activation The change in morphology and behavior of a T-helper 1 cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. CHEBI:131621 C19-steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131621 GO:0035712 T-helper 2 cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035712 Th2 cell activation The change in morphology and behavior of a T helper 2 cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. CHEBI:131622 steroidal acyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131622 GO:0045075 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045075 GO:0070031 alphav-beta5 integrin-osteopontin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070031 ITGAV-ITGB5-SPP1 complex A protein complex that consists of an alphav-beta5 integrin complex bound to osteopontin. GO:0045076 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045076 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070032 Vamp2-Snap25-Stx1a-Cplx1 complex|SNARE complex (Vamp2, Snap25, Stx1a, Cplx1) A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, and complexin I (or orthologs thereof). GO:0045073 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045073 GO:0045074 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045074 GO:0070030 alphav-beta1 integrin-osteopontin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070030 ITGAV-ITGB1-SPP1 complex A protein complex that consists of an alphav-beta1 integrin complex bound to osteopontin. GO:0045071 negative regulation of viral genome replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045071 down regulation of viral genome replication|inhibition of viral genome replication|down-regulation of viral genome replication|downregulation of viral genome replication Any process that stops, prevents, or reduces the frequency, rate or extent of viral genome replication. GO:0045072 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045072 GO:0045070 positive regulation of viral genome replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045070 upregulation of viral genome replication|stimulation of viral genome replication|up-regulation of viral genome replication|activation of viral genome replication|up regulation of viral genome replication Any process that activates or increases the frequency, rate or extent of viral genome replication. GO:0045079 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045079 GO:0045077 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045077 GO:0045078 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045078 GO:0070039 rRNA (guanosine-2'-O-)-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070039 Reactome:R-HSA-6793096|Reactome:R-HSA-6793122 Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methylguanosine. GO:0070037 rRNA (pseudouridine) methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070037 Reactome:R-HSA-6790906 Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a pseudouridine residue in an rRNA molecule. GO:0070038 rRNA (pseudouridine-N3-)-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070038 Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methylpseudouridine. GO:0070035 obsolete purine NTP-dependent helicase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070035 OBSOLETE. Catalysis of the reaction: purine NTP + H2O = purine NDP + phosphate, to drive the unwinding of a DNA or RNA helix. GO:0070036 obsolete GTP-dependent helicase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070036 OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate, to drive the unwinding of a DNA or RNA helix. GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070033 Vamp2-Snap25-Stx1a-Cplx2 complex|SNARE complex (Vamp2, Snap25, Stx1a, Cplx2) A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, and complexin II (or orthologs thereof). GO:0070034 telomerase RNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070034 TERC binding Interacting selectively and non-covalently with the telomerase RNA template. GO:0070020 obsolete transforming growth factor beta1-type II receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070020 TGF-beta receptor II-TGF-beta1 complex|TGF-beta1-type II receptor complex OBSOLETE. A protein complex that consists of a dimeric transforming growth factor beta (TGF-beta) type II receptor bound to a TGF-beta1 dimer. GO:0045086 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045086 GO:0045087 innate immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045087 Wikipedia:Innate_immune_system nonspecific immune response|innate immunity Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. GO:0070021 transforming growth factor beta ligand-receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070021 transforming growth factor beta1-type II receptor-type I receptor complex|TGFbeta2 ligand-receptor complex|TGFbeta1 ligand-receptor complex|TGF-beta1-type II receptor-type I receptor complex|TGFb ligand-receptor complex|TGF-beta2 ligand-receptor complex|TGF-beta1 ligand-receptor complex|TGF-beta ligand-receptor complex|TGFbeta1-beta2 ligand-receptor complex|TGFbeta ligand-receptor complex|TGF-beta1-beta2 ligand-receptor complex|TGF-beta 1:type II receptor:type I receptor complex|TGF-beta receptor II-TGF-beta receptor I-TGF-beta1 complex A protein complex that is formed by the association of a TGF-beta dimeric ligand with 2 molecules of each receptor molecule, TGF-beta type I receptor and TGF-beta type II receptor. The receptor molecules may form homo- or heterodimers but only once bound by the ligand. GO:0045084 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045084 GO:0045085 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045085 GO:0045082 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045082 GO:0045083 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045083 GO:0045080 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045080 PATO:0001908 multinucleate biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PATO_0001908 A nucleate quality inhering in a bearer by virtue of the bearer's having more than one nucleus. GO:0045081 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045081 GO:0045088 regulation of innate immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045088 Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection. GO:0045089 positive regulation of innate immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045089 upregulation of innate immune response|stimulation of innate immune response|up-regulation of innate immune response|up regulation of innate immune response Any process that activates or increases the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection. GO:0070028 obsolete regulation of transcription by carbon monoxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070028 regulation of transcription by CO OBSOLETE. Any process involving carbon monoxide that modulates the frequency, rate or extent of transcription. GO:0045090 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045090 GO:0070029 alphav-beta3 integrin-osteopontin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070029 ITGAV-ITGB3-SPP1 complex A protein complex that consists of an alphav-beta3 integrin complex bound to osteopontin. GO:0070026 nitric oxide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070026 NO binding|nitrogen monoxide binding|nitrosyl binding Interacting selectively and non-covalently with nitric oxide (NO). GO:0070027 carbon monoxide sensor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070027 Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of carbon monoxide (CO). GO:0070024 CD19-Vav-PIK3R1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070024 CD19-Vav-PI 3-kinase (p85 subunit) complex A protein complex that contains the cell surface signaling molecule CD19, the Ras guanine nucleotide exchange factor Vav, and the regulatory subunit alpha of phosphatidylinositol 3-kinase (PI3K). GO:0070025 carbon monoxide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070025 CO binding Interacting selectively and non-covalently with carbon monoxide (CO). UBERON:0037191 wall of membranous labyrinth biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0037191 membranous labyrinth wall GO:0070022 obsolete transforming growth factor beta receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070022 transforming growth factor beta receptor complex|TGF-beta receptor complex OBSOLETE. A homodimeric receptor complex that consists of two TGF-beta receptor monomers. GO:0070023 interleukin-12-interleukin-12 receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070023 IL12-IL12 receptor complex|IL12B-IL12RB1-IL12RB2 complex A protein complex that is formed by the association of a heterodimeric interleukin-12 receptor complex with an interleukin-12 heterodimer. GO:0070053 thrombospondin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070053 Combining with thrombospondin and transmitting the signal to initiate a change in cell activity. GO:0045097 obsolete basic/neutral keratin biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045097 type II intermediate filament|basic/neutral keratin OBSOLETE. A type of intermediate filament. GO:0070054 mRNA splicing, via endonucleolytic cleavage and ligation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070054 cytosolic mRNA splicing Splicing of mRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons. GO:0045098 type III intermediate filament biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045098 desmin|glial fibrillary acidic protein|vimentin|peripherin|type III intermediate filament associated protein A type of intermediate filament, typically made up of one or more of the proteins vimentin, desmin, glial fibrillary acidic protein (GFAP), and peripherin. Unlike the keratins, the type III proteins can form both homo- and heteropolymeric IF filaments. GO:0045095 keratin filament biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045095 acidic keratin|basic/neutral keratin A filament composed of acidic and basic keratins (types I and II), typically expressed in epithelial cells. The keratins are the most diverse classes of IF proteins, with a large number of keratin isoforms being expressed. Each type of epithelium always expresses a characteristic combination of type I and type II keratins. GO:0070051 fibrinogen binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070051 Interacting selectively and non-covalently with fibrinogen, a highly soluble hexameric glycoprotein complex that is found in blood plasma and is converted to fibrin by thrombin in the coagulation cascade. GO:0045096 obsolete acidic keratin biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045096 acidic keratin|type I intermediate filament OBSOLETE. A type of intermediate filament. GO:0070052 collagen V binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070052 Interacting selectively and non-covalently with a type V collagen trimer. GO:0045093 obsolete interleukin-18 alpha subunit binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045093 IL-18Ra binding OBSOLETE. Interacting selectively and non-covalently with the alpha subunit of interleukin-18. IL-18a is a component of IL-18 that is essential for IL-18 binding on the surface of T-helper 1 cells. GO:0070050 neuron cellular homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070050 neuron maintenance The cellular homeostatic process that preserves a neuron in a stable, differentiated functional and structural state. GO:0045094 obsolete interleukin-18 beta subunit binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045094 IL-18Rb binding OBSOLETE. Interacting selectively and non-covalently with the beta subunit of interleukin-18. IL-18b is a ligand non-binding chain and is required for signaling of IL-18 that binds with IL-18a. UBERON:0013191 ovarian cortex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013191 cortex of ovary|cortex ovarii (zona parenchymatosa) the layer of the ovarian stroma lying immediately beneath the tunica albuginea, composed of connective tissue cells and fibers, among which are scattered primary and secondary (antral) follicles in various stages of development; the cortex varies in thickness according to the age of the individual, becoming thinner with advancing years; included in the follicles are the cumulus oophorus, membrana granulosa (and the granulosa cells inside it), corona radiata, zona pellucida, and primary oocyte; the zona pellucida, theca of follicle, antrum and liquor folliculi are also contained in the follicle; also in the cortex is the corpus luteum derived from the follicles. UBERON:0013192 ovarian medulla biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013192 medulla of ovary|zona vasculosa of Waldeyer|medulla ovarii (zona vasculosa) highly vascular stroma found in the center of the ovary that forms from embryonic mesenchyme and contains blood vessels, lymphatic vessels, and nerves; this stroma forms the tissue of the hilum by which the ovarian ligament is attached, and through which the blood vessels enter; it does not contain any ovarian follicles. GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045091 regulation of retroviral genome replication Any process that modulates the frequency, rate or extent of single stranded viral RNA replication via double stranded DNA intermediate. GO:0045092 interleukin-18 receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045092 IL-18 receptor complex A protein complex that binds interleukin-18; comprises an alpha and a beta subunit. GO:0045099 obsolete vimentin biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045099 vimentin OBSOLETE. A type of intermediate filament. GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070059 ER stress-induced apoptosis|endoplasmic reticulum stress-induced apoptosis|apoptosis triggered by ER stress|apoptosis in response to ER stress|apoptosis in response to endoplasmic reticulum stress|intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen. GO:0070057 prospore membrane spindle pole body attachment site biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070057 forespore membrane spindle pole body attachment site|forespore membrane SPB attachment site|prospore membrane SPB attachment site The region of the prospore membrane to which the spindle pole body (SPB) is anchored; the prospore membrane extends from the SPB attachment site to surround the spore nucleus. GO:0070058 tRNA gene clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070058 The process in which tRNA genes, which are not linearly connected on the chromosome, are transported in three dimensions to, and maintained together in, the nucleolus. This clustered positioning leads to transcriptional silencing of nearby RNA polymerase II promoters (termed tRNA gene mediated (tgm) silencing) in S. cerevisiae. GO:0070055 obsolete mRNA endonucleolytic cleavage involved in unfolded protein response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070055 XBP1 mRNA cleavage|HAC1 mRNA cleavage|ERN1-mediated XBP-1 mRNA cleavage|IRE1-mediated XBP-1 mRNA cleavage|HAC1-type intron splice site recognition and cleavage OBSOLETE. The endonucleolytic cleavage of a mRNA containing an HAC1-type intron at the 5' and 3' splice sites. The cleavage step is part of unconventional mRNA splicing, and contributes to the endoplasmic reticulum unfolded protein response. GO:0070056 prospore membrane leading edge biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070056 forespore membrane leading edge The region of the prospore membrane that extends to surround the spore nucleus; coated with specific proteins that are thought to play a role in prospore membrane organization. GO:0070042 rRNA (uridine-N3-)-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070042 Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methyluridine. GO:0070043 rRNA (guanine-N7-)-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070043 Reactome:R-HSA-6790982 Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N7-methylguanine. GO:0070040 rRNA (adenine-C2-)-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070040 MetaCyc:RXN-11586|EC:2.1.1.192 Catalysis of the reaction: 2 S-adenosyl-L-methionine + adenine(2503) in 23S rRNA = S-adenosyl-L-homocysteine + 5'-deoxyadenosine + L-methionine + rRNA containing C2-methyladenine(2503) in 23S rRNA. GO:0070041 rRNA (uridine-C5-)-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070041 Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing C5-methyluridine. GO:0070048 endobrevin-SNAP-25-syntaxin-1a complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070048 SNARE complex (Stx1a, Snap25, Vamp8)|Stx1a-Snap25-Vamp8 complex A SNARE complex that contains endobrevin (VAMP8), SNAP-25, and syntaxin 1a (or orthologs thereof). GO:0070049 endobrevin-SNAP-25-syntaxin-2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070049 Stx2-Snap25-Vamp8 complex|SNARE complex (Stx2, Snap25, Vamp8) A SNARE complex that contains endobrevin (VAMP8), SNAP-25, and syntaxin 2 (or orthologs thereof). GO:0070046 synaptobrevin 2-SNAP-25-syntaxin-3 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070046 SNARE complex (Stx3, Snap25, Vamp2)|Stx3-Snap25-Vamp2 complex A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 3 (or orthologs thereof). GO:0070047 synaptobrevin 2-SNAP-25-syntaxin-4 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070047 SNARE complex (Stx4, Snap25, Vamp2)|Stx4-Snap25-Vamp2 complex A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 4 (or orthologs thereof). GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070044 Stx1a-SNAP25-VAMP complex|Snap25-Stx1a-Vamp2 complex|SNARE complex (Stx1a, SNAP25, VAMP)|SNARE complex (Snap25, Stx1a, Vamp2) A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 1a (or orthologs thereof). GO:0070045 synaptobrevin 2-SNAP-25-syntaxin-2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070045 SNARE complex (Stx2, Snap25, Vamp2)|Stx2-Snap25-Vamp2 complex A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 2 (or orthologs thereof). GO:0070075 tear secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070075 The regulated release of the aqueous layer of the tear film from the lacrimal glands. Tears are the liquid product of a process of lacrimation to clean and lubricate the eyes. Tear fluid contains water, mucin, lipids, lysozyme, lactoferrin, lipocalin, lacritin, immunoglobulins, glucose, urea, sodium, and potassium. GO:0070076 histone lysine demethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070076 The modification of a histone by the removal of a methyl group from a lysine residue. GO:0070073 clustering of voltage-gated calcium channels biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070073 voltage-gated calcium channel clustering|clustering of voltage-dependent calcium channels|clustering of voltage gated calcium channels The process in which voltage-gated calcium channels become localized together in high densities. GO:0070074 mononeme biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070074 A secretory organelle that forms part of the apical complex; a small, threadlike structure located is close proximity to the subpellicular microtubules. Its contents include a rhomboid protease (PfROM1 in Plasmodium falciparum) that moves from the lateral asymmetric localization to the merozoite apical pole and the posterior pole upon release of merozoites from schizonts. GO:0070071 proton-transporting two-sector ATPase complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070071 The aggregation, arrangement and bonding together of a proton-transporting two-sector ATPase complex, a large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070072 V-ATPase assembly|V-ATPase complex assembly The aggregation, arrangement and bonding together of a vacuolar proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across the vacuolar membrane. UBERON:0037144 wall of heart biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0037144 cardiac wall wall of organ which has as its parts the endocardium, myocardium , epicardium, and the cardiac septum, surrounded by the pericardial sac proper and is continuous with the walls of the systemic and pulmonary arterial and venous trees. GO:0070070 proton-transporting V-type ATPase complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070070 V-ATPase complex assembly|V-ATPase assembly The aggregation, arrangement and bonding together of a proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient. GO:0070079 histone H4-R3 demethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070079 The modification of histone H4 by the removal of a methyl group from arginine at position 3 of the histone. GO:0070077 histone arginine demethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070077 The modification of a histone by the removal of a methyl group from an arginine residue. GO:0070078 histone H3-R2 demethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070078 The modification of histone H3 by the removal of a methyl group from arginine at position 2 of the histone. GO:0070064 proline-rich region binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070064 Interacting selectively and non-covalently with a proline-rich region, i.e. a region that contains a high proportion of proline residues, in a protein. GO:0070065 cellubrevin-VAMP4-syntaxin-16 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070065 SNARE complex (Vamp3, Vamp4, Stx16)|Vamp3-Vamp4-Stx16 complex A SNARE complex that contains cellubrevin (VAMP3), VAMP4, and syntaxin 16 (or orthologs thereof). GO:0070062 extracellular exosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070062 exosome|extracellular vesicular exosome A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. GO:0070063 RNA polymerase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070063 Interacting selectively and non-covalently with an RNA polymerase molecule or complex. GO:0070060 'de novo' actin filament nucleation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070060 formin-mediated actin filament nucleation|unbranched actin filament nucleation The actin nucleation process in which actin monomers combine in the absence of any existing actin filaments; elongation of the actin oligomer formed by nucleation leads to the formation of an unbranched filament. GO:0070061 fructose binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070061 Interacting selectively and non-covalently with the D- or L-enantiomer of fructose, the ketohexose arabino-hex-2-ulose. GO:0035694 mitochondrial protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035694 catabolism of mitochondrial protein|degradation of damaged mitochondrial protein The chemical reactions and pathways resulting in the breakdown of a mitochondrial protein. This process is necessary to maintain the healthy state of mitochondria and is thought to occur via the induction of an intramitochondrial lysosome-like organelle that acts to eliminate the damaged oxidised mitochondrial proteins without destroying the mitochondrial structure. GO:0035695 mitophagy by induced vacuole formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035695 MIV-mediated mitophagy The process in which cells degrade mitochondria by inducing a vacuole-like structure which directly engulfs and degrades the unhealthy mitochondria by accumulating lysosomes. GO:0035696 monocyte extravasation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035696 The migration of a monocyte from the blood vessels into the surrounding tissue. GO:0035697 CD8-positive, alpha-beta T cell extravasation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035697 The migration of a CD8-positive, alpha-beta T cell from the blood vessels into the surrounding tissue. GO:0035698 CD8-positive, alpha-beta cytotoxic T cell extravasation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035698 The migration of a CD8-positive, alpha-beta cytotoxic T cell from the blood vessels into the surrounding tissue. GO:0035699 T-helper 17 cell extravasation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035699 The migration of a T-helper 17 cell from the blood vessels into the surrounding tissue. GO:0070068 VAMP4-syntaxin-6-syntaxin-16-Vti1a complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070068 Vamp4-Stx6-Stx16-Vti1a complex|SNARE complex (Vamp4, Stx6, Stx16, Vti1a) A SNARE complex that contains VAMP4, syntaxin 6, syntaxin 16, and Vti1a (or orthologs thereof). GO:0035690 cellular response to drug biolink:BiologicalProcess go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0035690 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease. GO:0070069 cytochrome complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070069 A protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions. GO:0035691 macrophage migration inhibitory factor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035691 macrophage migration inhibitory factor signalling pathway|MIF signaling pathway A series of molecular signals initiated by the binding of macrophage migration inhibitory factor to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0035692 macrophage migration inhibitory factor receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035692 A protein complex that binds macrophage migration inhibitory factor. Comprises CD74 and CD44 cell surface proteins. GO:0070066 cellubrevin-VAMP4-endobrevin-syntaxin-6 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070066 Vamp3-Vamp4-Vam8-Stx6 complex|SNARE complex (Vamp3, Vamp4, Vam8, Stx6) A SNARE complex that contains cellubrevin (VAMP3), VAMP4, endobrevin (VAMP8), and syntaxin 6 (or orthologs thereof). GO:0035693 NOS2-CD74 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035693 A protein complex comprising nitric oxide synthase 2 and CD74. This stable complex formation is thought to prevent CD74 degradation by caspases. GO:0070067 syntaxin-6-syntaxin-16-Vti1a complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070067 A SNARE complex that contains syntaxin 6, syntaxin 16, and Vti1a (or orthologs thereof). GO:0070097 delta-catenin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070097 Interacting selectively and non-covalently with the delta subunit of the catenin complex. GO:0070098 chemokine-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070098 chemokine-mediated signalling pathway A series of molecular signals initiated by the binding of a chemokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0070095 fructose-6-phosphate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070095 D-fructose 6-phosphate binding|fructose 6-phosphate binding Interacting selectively and non-covalently with fructose 6-phosphate. GO:0070096 mitochondrial outer membrane translocase complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070096 TOM complex assembly|mitochondrion outer membrane translocase complex assembly The aggregation, arrangement and bonding together of a set of components to form a mitochondrial outer membrane translocase complex. GO:0070093 negative regulation of glucagon secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070093 down-regulation of glucagon secretion|downregulation of glucagon secretion|down regulation of glucagon secretion|inhibition of glucagon secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of glucagon. GO:0070094 positive regulation of glucagon secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070094 up regulation of glucagon secretion|upregulation of glucagon secretion|stimulation of glucagon secretion|activation of glucagon secretion|up-regulation of glucagon secretion Any process that activates or increases the frequency, rate or extent of the regulated release of glucagon. GO:0070091 glucagon secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070091 The regulated release of glucagon from secretory granules in the A (alpha) cells of the pancreas (islets of Langerhans). GO:0070092 regulation of glucagon secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070092 Any process that modulates the frequency, rate or extent of the regulated release of glucagon. GO:0070090 metaphase plate biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070090 The intracellular plane, located halfway between the poles of the spindle, where chromosomes align during metaphase of mitotic or meiotic nuclear division. GO:0035683 memory T cell extravasation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035683 memory T-cell extravasation The migration of a memory T cell from the blood vessels into the surrounding tissue. A memory T cell is a distinctly differentiated long-lived T cell that has the phenotype CD45RO-positive and CD127-positive. GO:0035684 helper T cell extravasation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035684 helper T-cell extravasation|T-helper cell extravasation The migration of a helper T cell from the blood vessels into the surrounding tissue. A helper T-cell is an effector T cell that provides help in the form of secreted cytokines to other immune cells. GO:0035685 helper T cell diapedesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035685 T-helper cell diapedesis|helper T-cell diapedesis The passage of a helper T cell between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation. GO:0035686 sperm fibrous sheath biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035686 flagellum fibrous sheath|flagellar fibrous sheath A cytoskeletal structure surrounding the axoneme and outer dense fibers of the sperm flagellum. Consists of two longitudinal columns connected by closely arrayed semicircular ribs that assemble from distal to proximal throughout spermiogenesis. The fibrous sheath probably influences the degree of flexibility, plane of flagellar motion, and the shape of the flagellar beat. GO:0035687 T-helper 1 cell extravasation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035687 Th1 cell extravasation The migration of a T-helper 1 cell from the blood vessels into the surrounding tissue. A T-helper 1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma. GO:0035688 T-helper 1 cell diapedesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035688 Th1 cell diapedesis The passage of a T-helper 1 cell between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation. A T-helper 1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma. GO:0035689 chemokine (C-C motif) ligand 5 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035689 CCL5-mediated signaling pathway|chemokine (C-C motif) ligand 5 signalling pathway|RANTES-mediated signaling pathway A series of molecular signals initiated by the binding of the chemokine CCL5 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. CHEBI:131698 pregnane sterol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131698 NCBITaxon:33317 Protostomia organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_33317 CHEBI:131699 EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131699 GO:0035680 posterior lateral line neuromast hair cell morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035680 The change in form (cell shape and size) that occurs when a posterior lateral line neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. GO:0070099 regulation of chemokine-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070099 regulation of chemokine-mediated signalling pathway Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of a chemokine binding to a cell surface receptor. GO:0035681 toll-like receptor 15 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035681 toll-like receptor 15 signalling pathway|TLR15 signaling pathway Any series of molecular signals generated as a consequence of binding to toll-like receptor 15. GO:0035682 toll-like receptor 21 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035682 TLR21 signaling pathway|toll-like receptor 21 signalling pathway Any series of molecular signals generated as a consequence of binding to toll-like receptor 21. GO:0070086 ubiquitin-dependent endocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070086 ubiquitin-mediated endocytosis Endocytosis of a protein that requires the substrate to be modified by ubiquitination. Several plasma membrane proteins, including cell surface permeases and some receptors, are targeted for internalization by endocytosis, and are thereafter delivered to the vacuole or lysosome, where they are degraded. GO:0070087 chromo shadow domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070087 chromoshadow domain binding Interacting selectively and non-covalently with a chromo shadow domain, a protein domain that is distantly related, and found in association with, the chromo domain. GO:0070084 protein initiator methionine removal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070084 removal of initiator methionine from protein The protein modification process in which the translation-initiating methionine or formylmethionine residue is removed from a protein. GO:0070085 glycosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070085 Wikipedia:Glycosylation The covalent attachment and further modification of carbohydrate residues to a substrate molecule. GO:0070082 clathrin-sculpted monoamine transport vesicle lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070082 clathrin sculpted monoamine constitutive secretory pathway transport vesicle lumen|clathrin sculpted monoamine transport vesicle lumen The volume enclosed by the membrane of the clathrin-sculpted monoamine transport vesicle. GO:0070083 clathrin-sculpted monoamine transport vesicle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070083 clathrin sculpted monoamine transport vesicle membrane|clathrin sculpted monoamine constitutive secretory pathway transport vesicle membrane The lipid bilayer surrounding a clathrin-sculpted monoamine transport vesicle. GO:0070080 titin Z domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070080 Z repeat domain binding Interacting selectively and non-covalently with the titin Z domain, which recognizes and binds to the C-terminal calmodulin-like domain of alpha-actinin-2 (Act-EF34), adopts a helical structure, and binds in a groove formed by the two planes between the helix pairs of Act-EF34. GO:0070081 clathrin-sculpted monoamine transport vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070081 clathrin sculpted monoamine constitutive secretory pathway transport vesicle|clathrin sculpted monoamine transport vesicle A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing monoamines. CHEBI:141013 cob(II)inamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_141013 GO:0104004 cellular response to environmental stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0104004 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an environmental stimulus. GO:0104005 obsolete hijacked molecular function biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0104005 OBSOLETE. A function that was not selected for in the evolution of an organism, but arises from co-option by another organism, e.g. a human protein used as a virus receptor. CHEBI:141014 a pyrimidine ribonucleoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_141014 CHEBI:405237 L-canavanine zwitterion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_405237 GO:0035672 oligopeptide transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035672 oligopeptide membrane transport The process in which an oligopeptide is transported across a membrane. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages. GO:0035673 oligopeptide transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035673 oligopeptide transporter activity Enables the transfer of oligopeptides from one side of a membrane to the other. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages. GO:0035674 tricarboxylic acid transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035674 tricarboxylic acid membrane transport The process in which a tricarboxylic acid is transported across a membrane. GO:0035675 neuromast hair cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035675 The process whose specific outcome is the progression of a neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate. GO:0035676 anterior lateral line neuromast hair cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035676 The process whose specific outcome is the progression of an anterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate. GO:0035677 posterior lateral line neuromast hair cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035677 The process whose specific outcome is the progression of a posterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate. GO:0035678 neuromast hair cell morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035678 The change in form (cell shape and size) that occurs when a neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. GO:0035679 anterior lateral line neuromast hair cell morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035679 The change in form (cell shape and size) that occurs when an anterior lateral line neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. GO:0070088 PHA granule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070088 polyhydroxyalkanoate granule|PHB granule An inclusion body located in the cytoplasm that consists of polyhydroxyalkanoate (PHA) molecules and associated proteins, surrounded by a phospholipid monolayer; the proteins include PHA synthase, PHA depolymerase and 3HB-oligomer hydroxylase, phasins (PhaPs), which are thought to be the major structural proteins of the membrane surrounding the inclusion, and the regulator of phasin expression PhaR. GO:0035670 plant-type ovary development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035670 The process whose specific outcome is the progression of an ovary that produces an ovule over time, from its formation to the mature structure. The ovary is the enlarged basal portion of a carpel and matures into a fruit. An ovule is the multicellular structure that gives rise to and contains the female reproductive cells, and develops into a seed. GO:0035671 enone reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035671 MetaCyc:RXN-12267 Catalysis of the reaction: an enone + NADPH + H+ = a ketone + NADP+. GO:0070089 chloride-activated potassium channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070089 Enables the chloride concentration-regulatable energy-independent passage of potassium ions across a lipid bilayer down a concentration gradient. GO:1901729 monensin A catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901729 monensin catabolism|monensin degradation|monensin A catabolism|monensin A degradation|monensin breakdown|monensin A breakdown The chemical reactions and pathways resulting in the breakdown of monensin A. GO:1901727 positive regulation of histone deacetylase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901727 up regulation of histone deacetylase activity|upregulation of histone deacetylase activity|activation of histone deacetylase activity|up-regulation of histone deacetylase activity Any process that activates or increases the frequency, rate or extent of histone deacetylase activity. GO:1901728 monensin A metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901728 monensin metabolism|monensin A metabolism The chemical reactions and pathways involving monensin A. GO:1901725 regulation of histone deacetylase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901725 Any process that modulates the frequency, rate or extent of histone deacetylase activity. GO:1901726 negative regulation of histone deacetylase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901726 down-regulation of histone deacetylase activity|downregulation of histone deacetylase activity|down regulation of histone deacetylase activity|inhibition of histone deacetylase activity Any process that stops, prevents or reduces the frequency, rate or extent of histone deacetylase activity. GO:1901723 negative regulation of cell proliferation involved in kidney development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901723 down regulation of cell proliferation involved in kidney development|downregulation of cell proliferation involved in kidney development|down-regulation of cell proliferation involved in kidney development|inhibition of cell proliferation involved in kidney development Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in kidney development. GO:1901724 positive regulation of cell proliferation involved in kidney development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901724 up regulation of cell proliferation involved in kidney development|activation of cell proliferation involved in kidney development|up-regulation of cell proliferation involved in kidney development|upregulation of cell proliferation involved in kidney development Any process that activates or increases the frequency, rate or extent of cell proliferation involved in kidney development. CHEBI:85480 O-butenoyl-L-carnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85480 GO:1901721 positive regulation of NMS complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901721 up regulation of KMN complex interaction involved in chromosome segregation|upregulation of NMS complex association involved in chromosome segregation|upregulation of KMN network assembly involved in chromosome segregation|up regulation of NMS complex interaction involved in chromosome segregation|upregulation of KMN complex interaction involved in chromosome segregation|up-regulation of NMS complex association involved in chromosome segregation|positive regulation of NMS complex assembly involved in kinetochore assembly|up regulation of KMN network assembly involved in chromosome segregation|positive regulation of KMN network assembly involved in chromosome segregation|activation of NMS complex association involved in chromosome segregation|upregulation of NMS complex interaction involved in chromosome segregation|up-regulation of KMN complex interaction involved in chromosome segregation|activation of KMN complex assembly involved in chromosome segregation|positive regulation of NMS complex association involved in chromosome segregation|activation of KMN network assembly involved in chromosome segregation|up regulation of NMS complex association involved in chromosome segregation|up-regulation of KMN network assembly involved in chromosome segregation|up-regulation of NMS complex interaction involved in chromosome segregation|activation of NMS complex interaction involved in chromosome segregation|positive regulation of KMN complex interaction involved in chromosome segregation Any process that activates or increases the frequency, rate or extent of NMS complex assembly. The NMS complex is involved in chromosome segregation. UBERON:0013136 vein of lip biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013136 vena labialis|labial vein|lip vein|labial vein of face A vein that drains a lip. CHEBI:85481 4-hydroxy-6-(14-hydroxytetradecyl)-pyran-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85481 CHEBI:36508 glycotriaosylceramide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36508 GO:1901722 regulation of cell proliferation involved in kidney development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901722 Any process that modulates the frequency, rate or extent of cell proliferation involved in kidney development. CHEBI:85482 6-(hexadecan-2-yl)-4-hydroxy-pyran-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85482 CHEBI:85483 4-hydroxy-6-(2-methyldecyl)-pyran-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85483 GO:1901720 negative regulation of NMS complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901720 inhibition of KMN network assembly involved in chromosome segregation|down-regulation of NMS complex interaction involved in chromosome segregation|downregulation of KMN complex interaction involved in chromosome segregation|inhibition of NMS complex association involved in chromosome segregation|down regulation of KMN complex assembly involved in chromosome segregation|down regulation of KMN network assembly involved in chromosome segregation|downregulation of NMS complex interaction involved in chromosome segregation|downregulation of KMN network assembly involved in chromosome segregation|inhibition of KMN complex interaction involved in chromosome segregation|down regulation of NMS complex interaction involved in chromosome segregation|negative regulation of NMS complex assembly involved in kinetochore assembly|inhibition of NMS complex interaction involved in chromosome segregation|negative regulation of NMS complex association involved in chromosome segregation|down-regulation of NMS complex association involved in chromosome segregation|down-regulation of KMN network assembly involved in chromosome segregation|negative regulation of KMN network assembly involved in chromosome segregation|down-regulation of KMN complex interaction involved in chromosome segregation|negative regulation of KMN complex interaction involved in chromosome segregation|downregulation of NMS complex association involved in chromosome segregation|down regulation of NMS complex association involved in chromosome segregation Any process that stops, prevents or reduces the frequency, rate or extent of NMS complex assembly. The NMS complex is involved in chromosome segregation. UBERON:0013139 ligament of liver biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013139 liver ligament|hepatic ligament A nonskeletal ligament that is part of a liver. CHEBI:36507 D-galactosyl-N-acetyl-D-glucosaminyl-D-galactosyl-D-glucosylceramide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36507 CHEBI:85484 4-hydroxy-6-(11-methylheptadecyl)-pyran-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85484 CHEBI:85485 4-hydroxy-6-(11-methyldodecyl)-pyran-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85485 CHEBI:85488 chloroeremomycin(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85488 CHEBI:85489 cis-3-enoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85489 CHEBI:36500 glucosylceramide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36500 CHEBI:36501 (2Z,4Z)-5-carboxypenta-2,4-dienoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36501 GO:0060630 obsolete regulation of M/G1 transition of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060630 regulation of M/G1 transition of mitotic cell cycle OBSOLETE. Any process that modulates the rate, frequency, or extent of M/G1 transition of the mitotic cell cycle, the progression from M phase to G1 phase of the mitotic cell cycle. GO:0060631 regulation of meiosis I biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060631 Any process that modulates the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells. GO:0060632 regulation of microtubule-based movement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060632 Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins. CHEBI:36504 5-carboxypenta-2,4-dienoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36504 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060633 Any process that decreases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter. CHEBI:36505 labdane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36505 GO:0060634 regulation of 4,6-pyruvylated galactose residue biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060634 Any process that modulates the rate, frequency, or extent of 4,6-pyruvylated galactose residue biosynthetic process, the chemical reactions and pathways resulting in the formation of the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-(1->3)-. The galactose residue is part of a larger polysaccharide chain. GO:0060635 positive regulation of (1->3)-beta-D-glucan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060635 positive regulation of 1,3-beta-D-glucan biosynthetic process Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans. CHEBI:12532 N,N-dihydroxy-L-tyrosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_12532 CHEBI:36503 menthone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36503 GO:0060636 negative regulation of (1->3)-beta-D-glucan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060636 negative regulation of 1,3-beta-D-glucan biosynthetic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans. GO:0060637 positive regulation of lactation by mesenchymal-epithelial cell signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060637 positive regulation of lactation by mesenchymal-epithelial cell signalling The process that increases the rate, frequency, or extent of lactation as a result of the secretion of a signal from the mammary fat and its reception by a mammary epithelial cell. GO:0060638 mesenchymal-epithelial cell signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060638 mesenchymal-epithelial cell signalling Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted. GO:0060639 positive regulation of salivary gland formation by mesenchymal-epithelial signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060639 positive regulation of salivary gland formation by mesenchymal-epithelial signalling Any process that induces the formation of the salivary gland field by means of the secretion of a signal by a mesenchymal cell and its reception and interpretation by an epithelial cell resulting in it adopting the identity of a salivary gland bud cell. GO:1901738 regulation of vitamin A metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901738 regulation of vitamin A metabolism Any process that modulates the frequency, rate or extent of vitamin A metabolic process. GO:1901739 regulation of myoblast fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901739 Any process that modulates the frequency, rate or extent of myoblast fusion. GO:1901736 (R)-mevalonic acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901736 (R)-mevalonic acid breakdown|(R)-mevalonic acid catabolism|(R)-mevalonate degradation|(R)-mevalonate breakdown|(R)-mevalonate catabolism|(R)-mevalonic acid degradation The chemical reactions and pathways resulting in the breakdown of (R)-mevalonic acid. GO:1901737 (R)-mevalonic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901737 (R)-mevalonic acid biosynthesis|(R)-mevalonic acid anabolism|(R)-mevalonic acid synthesis|(R)-mevalonic acid formation|(R)-mevalonate biosynthesis|(R)-mevalonate anabolism|(R)-mevalonate synthesis The chemical reactions and pathways resulting in the formation of (R)-mevalonic acid. GO:1901734 quercetin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901734 quercetin biosynthesis|quercetin anabolism|quercetin synthesis|quercetin formation The chemical reactions and pathways resulting in the formation of quercetin. GO:1901735 (R)-mevalonic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901735 (R)-mevalonic acid metabolism|(R) mevalonate metabolism The chemical reactions and pathways involving (R)-mevalonic acid. PR:000022358 adenylate cyclase biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000022358 cyaA|ATP pyrophosphate-lyase|cya|adenylyl cyclase A protein that is a translation product of the Escherichia coli K-12 cyaA gene or a 1:1 ortholog thereof. GO:1901732 quercetin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901732 quercetin metabolism The chemical reactions and pathways involving quercetin. GO:0045006 DNA deamination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045006 The removal of an amino group from a nucleotide base in DNA. An example is the deamination of cytosine to produce uracil. CHEBI:85471 cobalt(II)-factor IV(6-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85471 GO:1901733 quercetin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901733 quercetin catabolism|quercetin breakdown|quercetin degradation The chemical reactions and pathways resulting in the breakdown of quercetin. UBERON:0013126 vein of abdomen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013126 abdominal vein A vein that is part of a abdomen. GO:0045007 depurination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045007 Wikipedia:Depurination The disruption of the bond between the sugar in the backbone and the A or G base, causing the base to be removed and leaving a depurinated sugar. CHEBI:85472 O-hydroxybutyryl-L-carnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85472 GO:1901730 monensin A biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901730 monensin A biosynthesis|monensin anabolism|monensin A anabolism|monensin synthesis|monensin A synthesis|monensin formation|monensin A formation|monensin biosynthesis The chemical reactions and pathways resulting in the formation of monensin A. CHEBI:36517 germacrene A biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36517 GO:0045004 DNA replication proofreading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045004 Correction of replication errors by DNA polymerase using a 3'-5' exonuclease activity. GO:0045005 DNA-dependent DNA replication maintenance of fidelity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045005 maintenance of fidelity involved in DNA-dependent DNA replication|maintenance of fidelity during DNA-dependent DNA replication A DNA metabolic process that prevents or corrects errors to ensure that DNA is replicated accurately. Errors can be corrected either by intrinsic DNA polymerase proofreading activity or via mismatch repair. GO:1901731 positive regulation of platelet aggregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901731 up-regulation of thrombocyte aggregation|positive regulation of blood platelet aggregation|up regulation of blood platelet aggregation|up regulation of platelet aggregation|upregulation of thrombocyte aggregation|upregulation of blood platelet aggregation|up regulation of thrombocyte aggregation|upregulation of platelet aggregation|positive regulation of thrombocyte aggregation|up-regulation of blood platelet aggregation|activation of blood platelet aggregation|activation of thrombocyte aggregation|up-regulation of platelet aggregation|activation of platelet aggregation Any process that activates or increases the frequency, rate or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules. CHEBI:85474 4-hydroxy-6-(2-hydroxytridecyl)-pyran-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85474 UBERON:0013121 proximal epiphysis of phalanx of pes biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013121 basal epiphysis of phalanx of foot|basis phalangis pedis|basis phalangis (pedis)|proximal epiphysis of phalanx of toe|base of phalanx of foot GO:0045002 double-strand break repair via single-strand annealing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045002 Repair of a DSB made between two repeated sequences oriented in the same direction occurs primarily by the single strand annealing pathway. The ends of the break are processed by a 5' to 3' exonuclease, exposing complementary single-strand regions of the direct repeats that can anneal, resulting in a deletion of the unique DNA between the direct repeats. CHEBI:85475 4-hydroxy-6-(11-hydroxyheptadecyl)-pyran-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85475 UBERON:0013122 distal epiphysis of phalanx of pes biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013122 head of phalanx of foot|ungual tuberosity of distal phalanx of toe|distal epiphysis of phalanx of toe|caput phalangis pedis|distal end of phalanx of foot|caput phalangis (pedis) GO:0045003 double-strand break repair via synthesis-dependent strand annealing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045003 SDSA|mitotic gene conversion SDSA is a major mechanism of double-strand break repair in mitosis which allows for the error-free repair of a double-strand break without the exchange of adjacent sequences. The broken DNA searches for and base pairs with a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template. Newly synthesized DNA is then displaced from the template and anneal with its complement on the other side of the double-strand break. CHEBI:85477 4-hydroxy-6-(15-hydroxypentadecyl)-pyran-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85477 GO:0045001 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045001 CHEBI:85479 4-hydroxy-6-(non-8-en-1-yl)-pyran-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85479 GO:0060620 regulation of cholesterol import biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060620 Any process that modulates the rate, frequency or extent of cholesterol import. Cholesterol import is the directed movement of cholesterol into a cell or organelle. CHEBI:36515 (-)-germacrene A biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36515 UBERON:0013118 sulcus of brain biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013118 fissure of brain|sulcus|sulci & spaces|cerebral sulcus|cerebral sulci|cerebral sulci A depression or fissure in the surface of the brain. It surrounds the gyri, creating the characteristic appearance of the brain in humans and other large mammals. GO:0060621 negative regulation of cholesterol import biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060621 Any process that decreases the rate, frequency or extent of cholesterol import. Cholesterol import is the directed movement of cholesterol into a cell or organelle. GO:0060622 regulation of ascospore wall beta-glucan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060622 Any process that modulates the rate, frequency or extent of ascospore wall beta-glucan biosynthetic process, the chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores. CHEBI:36513 cadinane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36513 GO:0045008 depyrimidination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045008 The disruption of the bond between the sugar in the backbone and the C or T base, causing the base to be removed and leaving a depyrimidinated sugar. GO:0060623 regulation of chromosome condensation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060623 Any process that modulates the rate, frequency, or extent of chromosome condensation, the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells. CHEBI:36514 germacrane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36514 GO:0060624 regulation of ascospore wall (1->3)-beta-D-glucan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060624 regulation of ascospore wall 1,3-beta-glucan biosynthetic process|regulation of ascospore wall 1,3-beta-D-glucan biosynthetic process Any process that modulates the rate, frequency, or extent of ascospore wall (1->3)-beta-D-glucan biosynthetic process, the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D--glucosidic bonds, found in the walls of ascospores. GO:0045009 chitosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045009 An intracellular membrane-bounded particle found in fungi and containing chitin synthase; it synthesizes chitin microfibrils. Chitin synthase activity exists in chitosomes and they are proposed to act as a reservoir for regulated transport of chitin synthase enzymes to the division septum. GO:0060625 regulation of protein deneddylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060625 regulation of cullin deneddylation Any process that modulates the rate, frequency, or extent of protein deneddylation, the removal of a ubiquitin-like protein of the NEDD8 type from a protein. GO:0060626 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0060626 GO:0060627 regulation of vesicle-mediated transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060627 Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell. GO:0060628 regulation of ER to Golgi vesicle-mediated transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060628 Any process that modulates the rate, frequency, or extent of ER to Golgi vesicle-mediated transport, the directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi. GO:0060629 regulation of homologous chromosome segregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060629 Any process that modulates the rate, frequency, or extent of homologous chromosome segregation, the cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets. GO:0045010 actin nucleation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045010 actin filament nucleation The initial step in the formation of an actin filament, in which actin monomers combine to form a new filament. Nucleation is slow relative to the subsequent addition of more monomers to extend the filament. GO:1901749 leukotriene D4 catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901749 leukotriene D4 catabolism|leukotriene D4 degradation|leukotriene D4 breakdown The chemical reactions and pathways resulting in the breakdown of leukotriene D4. GO:1901747 prephenate(2-) biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901747 prephenate(2-) biosynthesis|prephenate(2-) anabolism|prephenate anabolism|prephenate(2-) synthesis|prephenate(2-) formation|prephenate synthesis|prephenate formation|prephenate biosynthesis The chemical reactions and pathways resulting in the formation of prephenate(2-). GO:1901748 leukotriene D4 metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901748 leukotriene D4 metabolism The chemical reactions and pathways involving leukotriene D4. GO:1901745 prephenate(2-) metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901745 prephenate(2-) metabolism|prephenate metabolism The chemical reactions and pathways involving prephenate(2-). GO:1901746 prephenate(2-) catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901746 prephenate degradation|prephenate(2-) breakdown|prephenate breakdown|prephenate catabolism|prephenate(2-) catabolism|prephenate(2-) degradation The chemical reactions and pathways resulting in the breakdown of prephenate(2-). GO:0045017 glycerolipid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045017 glycerolipid anabolism|glycerolipid biosynthesis|glycerolipid synthesis|glycerolipid formation The chemical reactions and pathways resulting in the formation of glycerolipids, any lipid with a glycerol backbone. GO:1901743 2-deoxystreptamine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901743 2-deoxystreptamine degradation|2-deoxystreptamine breakdown|2-deoxystreptamine catabolism The chemical reactions and pathways resulting in the breakdown of 2-deoxystreptamine. GO:1901744 2-deoxystreptamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901744 2-deoxystreptamine formation|2-deoxystreptamine biosynthesis|2-deoxystreptamine anabolism|2-deoxystreptamine synthesis The chemical reactions and pathways resulting in the formation of 2-deoxystreptamine. GO:0045018 retrograde transport, vacuole to Golgi biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045018 retrograde transport from the vacuole The directed movement of substances from the vacuole to the trans-Golgi network; this occurs in yeast via the prevacuolar/endosomal compartment. GO:1901741 positive regulation of myoblast fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901741 up regulation of myoblast fusion|activation of myoblast fusion|up-regulation of myoblast fusion|upregulation of myoblast fusion Any process that activates or increases the frequency, rate or extent of myoblast fusion. GO:0045015 HDEL sequence binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045015 HDEL receptor activity Interacting selectively and non-covalently with a HDEL sequence, the C terminus tetrapeptide sequence His-Asp-Glu-Leu found in proteins that are to be retained in the endoplasmic reticulum. GO:1901742 2-deoxystreptamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901742 2-deoxystreptamine metabolism The chemical reactions and pathways involving 2-deoxystreptamine. GO:0045016 mitochondrial magnesium ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045016 mitochondrial magnesium ion transport The process in which a magnesium ion (Mg2+) is transported across a mitochondrial membrane, into or out of the mitochondrion. GO:0045013 carbon catabolite repression of transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045013 negative regulation of transcription by carbon catabolites|carbon catabolite repression A transcription regulation process in which the presence of one carbon source leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances. GO:1901740 negative regulation of myoblast fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901740 down-regulation of myoblast fusion|inhibition of myoblast fusion|down regulation of myoblast fusion|downregulation of myoblast fusion Any process that stops, prevents or reduces the frequency, rate or extent of myoblast fusion. GO:0045014 carbon catabolite repression of transcription by glucose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045014 down-regulation of transcription by glucose|glucose repression|downregulation of transcription by glucose|down regulation of transcription by glucose|glucose effect|inhibition of transcription by glucose A transcription regulation process in which the presence of glucose leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances. GO:0045011 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045011 GO:0045012 obsolete MHC class II receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045012 MHC class II receptor activity|major histocompatibility complex class II receptor|class II major histocompatibility complex antigen OBSOLETE. A major histocompatibility complex class II receptor. These display processed antigens from virally-infected or transformed cells. Class-II-positive cells ('antigen-presenting cells') can take up antigens from outside by endocytosis, degrade them into small peptides, and re-export the peptides (now bound to MHC class II protein) to the cell surface. These peptide-MHC class II complexes can then be recognized by specific CD4+ lymphocytes. GO:0060650 epithelial cell proliferation involved in mammary gland bud elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060650 The multiplication or reproduction of mammary gland bud epithelial cells, resulting in the elongation of the bud. GO:0060651 regulation of epithelial cell proliferation involved in mammary gland bud elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060651 Any process that modulates the frequency, rate or extent of mammary gland bud epithelial cell proliferation that results in the elongation of the bud. GO:0060652 mammary gland cord morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060652 mammary gland sprout morphogenesis The process in which anatomical structures of the mammary gland cord are generated and organized. Mammary gland cords form when the mammary gland bud invades the mammary fat. GO:0060653 epithelial cell differentiation involved in mammary gland cord morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060653 epithelial cell differentiation involved in mammary gland sprout morphogenesis The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland cord. Epithelial cells of the mammary cord give it its funnel-like shape and some are cornified. GO:0060654 mammary gland cord elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060654 The process in which the mammary gland sprout grows along its axis. GO:0060655 branching involved in mammary gland cord morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060655 The process in which the branching structure of the mammary gland cord is generated and organized. The mammary gland cord is a solid epithelial structure that will hollow out, forming the mammary duct. GO:0060656 regulation of branching involved in mammary cord morphogenesis by fat precursor cell-epithelial cell signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060656 regulation of branching involved in mammary cord morphogenesis by fat precursor cell-epithelial cell signalling Any process that modulates the rate, frequency, or extent of branching of the mammary gland cord as a result of a signal being created by a mammary fat precursor cell and its subsequent reception and interpretation by a mammary cord epithelial cell. GO:0045019 negative regulation of nitric oxide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045019 negative regulation of nitric oxide biosynthesis|down-regulation of nitric oxide biosynthetic process|inhibition of nitric oxide biosynthetic process|negative regulation of nitric oxide anabolism|down regulation of nitric oxide biosynthetic process|negative regulation of nitric oxide synthesis|negative regulation of nitric oxide formation|downregulation of nitric oxide biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide. GO:0060657 regulation of mammary gland cord elongation by mammary fat precursor cell-epithelial cell signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060657 regulation of mammary gland cord elongation by mammary fat precursor cell-epithelial cell signalling Any process that modulates the rate, frequency, or extent of mammary gland cord elongation as a result of a signal being created by a mesenchymal cell that is a precursor to the mammary fat and its subsequent reception and interpretation by an mammary cord epithelial cell. GO:0060658 nipple morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060658 The process in which the nipple is generated and organized. GO:0060659 nipple sheath formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060659 The developmental process pertaining to the initial formation of the nipple sheath from the unspecified epidermis. This process begins with a circular ingrowth of the epidermis around the region of the mammary sprout. It ends before the region begins to elevate. GO:0045020 obsolete error-prone DNA repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045020 mutagenic DNA repair|error-prone DNA repair OBSOLETE. DNA repair pathways that tend to increase the endogenous mutation rate. NCBITaxon:33340 Neoptera organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_33340 GO:0045021 obsolete error-free DNA repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045021 error-free DNA repair OBSOLETE. DNA repair pathways that do not increase the mutation rate above spontaneous background levels, e.g. excision and recombination pathways. GO:1901758 butirosin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901758 butirosin synthesis|butirosin formation|butirosin biosynthesis|butirosin anabolism The chemical reactions and pathways resulting in the formation of butirosin. GO:1901759 beta-L-Ara4N-lipid A metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901759 4-amino-4-deoxy-beta-L-arabinose-lipid A metabolic process|beta-L-Ara4N-lipid A metabolism|4-amino-4-deoxy-beta-L-arabinose-lipid A metabolism The chemical reactions and pathways involving beta-L-Ara4N-lipid A. GO:1901756 butirosin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901756 butirosin metabolism The chemical reactions and pathways involving butirosin. CHEBI:85490 4-hydroxy-6-(13-hydroxy-2-oxononadecyl)pyran-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85490 CHEBI:85491 epivancomycin(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85491 GO:1901757 butirosin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901757 butirosin catabolism|butirosin degradation|butirosin breakdown The chemical reactions and pathways resulting in the breakdown of butirosin. GO:1901754 vitamin D3 catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901754 vitamin D3 degradation|vitamin D3 breakdown|calciol catabolism|cholecalciferol catabolic process|calciol degradation|vitamin D3 catabolism|calciol breakdown|cholecalciferol catabolism|calciol catabolic process The chemical reactions and pathways resulting in the breakdown of vitamin D3. GO:0045028 G protein-coupled purinergic nucleotide receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045028 G-protein coupled purinergic nucleotide receptor activity|P2Y receptor|purinergic nucleotide receptor activity, G-protein coupled|purinergic nucleotide receptor activity, G protein coupled|P2Y|G protein coupled purinergic nucleotide receptor activity Combining with a purine nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. CHEBI:85492 4-hydroxy-6-(17-hydroxy-2-oxoheptadecyl)pyran-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85492 GO:1901755 vitamin D3 biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901755 calciol synthesis|calciol formation|calciol biosynthesis|calciol biosynthetic process|vitamin D3 anabolism|vitamin D3 synthesis|vitamin D3 biosynthesis|vitamin D3 formation|cholecalciferol biosynthesis|cholecalciferol biosynthetic process|calciol anabolism The chemical reactions and pathways resulting in the formation of vitamin D3. GO:0045029 G protein-coupled UDP receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045029 UDP-activated nucleotide receptor activity Combining with a nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity, activated by UDP. CHEBI:85493 4-saturated-trans-3-enoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85493 GO:1901752 leukotriene A4 catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901752 leukotriene A4 breakdown|leukotriene A4 catabolism|leukotriene A4 degradation The chemical reactions and pathways resulting in the breakdown of leukotriene A4. GO:0045026 plasma membrane fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045026 cell fusion|cell-cell fusion The joining of the lipid bilayer membrane that surround a cell with that of another cell, producing a single cell. CHEBI:85494 4-hydroxy-6-(2-oxoundec-10-en-1-yl)pyran-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85494 CHEBI:85495 4-hydroxy-6-(16-hydroxy-2-oxohexadecyl)pyran-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85495 GO:1901753 leukotriene A4 biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901753 leukotriene A4 anabolism|leukotriene A4 synthesis|leukotriene A4 formation|leukotriene A4 biosynthesis The chemical reactions and pathways resulting in the formation of leukotriene A4. GO:0045027 DNA end binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045027 Interacting selectively and non-covalently with the ends of DNA that are exposed by the creation of double-strand breaks (DSBs). GO:0045024 obsolete peptidyl-glutamyl peptide hydrolyzing enzyme activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045024 peptidyl-glutamyl peptide hydrolyzing enzyme activity OBSOLETE. Catalysis of the cleavage of bonds after acidic amino acids and after branched chain amino acids. CHEBI:85496 4-hydroxy-6-(3-methyl-2-oxoheptadecyl)pyran-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85496 GO:1901750 leukotriene D4 biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901750 leukotriene D4 anabolism|leukotriene D4 synthesis|leukotriene D4 formation|leukotriene D4 biosynthesis The chemical reactions and pathways resulting in the formation of leukotriene D4. GO:0045025 mitochondrial degradosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045025 mtEXO A mitochondrial protein complex with 3' to 5' exoribonuclease activity that participates in intron-independent turnover and processing of mitochondrial transcripts. In humans, the mitochondrial degradosome is a pentameric complex, and in yeast it exists as a heterodimer. GO:1901751 leukotriene A4 metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901751 leukotriene A4 metabolism The chemical reactions and pathways involving leukotriene A4. CHEBI:85497 4-hydroxy-6-(4-methyl-2-oxododecyl)pyran-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85497 GO:0045022 early endosome to late endosome transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045022 The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the late sorting endosomes; transport occurs along microtubules and can be experimentally blocked with microtubule-depolymerizing drugs. CHEBI:85498 4-hydroxy-6-(13-methyl-2-oxononadecyl)pyran-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85498 GO:0045023 G0 to G1 transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045023 The mitotic cell cycle phase transition whose occurrence commits the cell from the G0 quiescent state to the G1 phase. Under certain conditions, cells exit the cell cycle during G1 and remain in the G0 state as nongrowing, non-dividing (quiescent) cells. Appropriate stimulation of such cells induces them to return to G1 and resume growth and division. The G0 to G1 transition is accompanied by many changes in the program of gene expression. CHEBI:85499 4-hydroxy-6-(13-methyl-2-oxotetradecyl)pyran-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85499 GO:0060640 positive regulation of dentin-containing tooth bud formation by mesenchymal-epithelial signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060640 positive regulation of dentine-containing tooth bud formation by mesenchymal-epithelial signalling|positive regulation of dentine-containing tooth bud formation by mesenchymal-epithelial signaling Any process that initiates the formation of a tooth bud by the secretion of a signal from a mesenchymal cell and its reception and subsequent change in the identity of an epithelial cell of the tooth bud. GO:0060641 mammary gland duct regression in males biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060641 The process in which the epithelium of the mammary duct is destroyed in males. GO:0060642 white fat cell differentiation involved in mammary gland fat development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060642 The process in which a preadipocyte acquires specialized features of a white adipocyte of the mammary gland. White adipocytes have cytoplasmic lipids arranged in a unique vacuole. GO:0060643 epithelial cell differentiation involved in mammary gland bud morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060643 The process in which a cell of the mammary placode becomes a cell of the mammary gland bud. GO:0060644 mammary gland epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060644 The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland. GO:0060645 peripheral mammary gland bud epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060645 The process in which a relatively unspecialized epithelial cell of the mammary placode becomes an epithelial cell at the periphery of the mammary gland bud. Cells at the periphery of the bud are larger that those of the surrounding epithelium and are arranged concentrically. GO:0060646 internal mammary gland bud epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060646 The process in which a relatively unspecialized epithelial cell of the mammary placode becomes an internal epithelial cell of the mammary gland bud. Internal cells are small and of irregular shape. GO:0060647 mesenchymal cell condensation involved in mammary fat development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060647 The cell adhesion process in which mammary mesenchyme cells adhere to one another in the initial stages of the formation of mammary fat development. GO:0060648 mammary gland bud morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060648 The process in which anatomical structures of the mammary gland buds are generated and organized. Mammary gland buds form by an outpocketing of the mammary placodes and grow to invade the mammary fat, when they form the mammary cord. GO:0060649 mammary gland bud elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060649 The process in which the mammary gland bud grows along its axis. GO:0045031 G protein-coupled ATP receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045031 ATP-activated adenosine receptor activity|ATP-activated nucleotide receptor activity Combining with ATP and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. GO:0045032 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045032 GO:0045030 G protein-coupled UTP receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045030 uridine nucleotide receptor activity|UTP-activated nucleotide receptor activity|purinoceptor type U Combining with a nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity, activated by UTP. GO:1901769 carbapenem biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901769 carbapenem anabolism|carbapenem synthesis|carbapenem formation|carbapenem biosynthesis The chemical reactions and pathways resulting in the formation of carbapenem. GO:1901767 carbapenem metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901767 carbapenem metabolism The chemical reactions and pathways involving carbapenem. GO:1901768 carbapenem catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901768 carbapenem degradation|carbapenem breakdown|carbapenem catabolism The chemical reactions and pathways resulting in the breakdown of carbapenem. GO:1901765 phosphinothricin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901765 phosphinothricin degradation|phosphinothricin catabolism|phosphinothricin breakdown The chemical reactions and pathways resulting in the breakdown of phosphinothricin. GO:0045039 protein insertion into mitochondrial inner membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045039 protein import into mitochondrial inner membrane|mitochondrial inner membrane protein import|protein transport into mitochondrial inner membrane The processes mediating the insertion of proteins into the mitochondrial inner membrane. Mitochondrial inner membrane proteins can get inserted from the cytosol, by crossing the outer membrane and being guided by an inner membrane translocase complex into their final destination in the inner membrane. Some proteins present in the intermembrane space can get inserted into the inner mitochondrial membrane. Finally, some proteins are inserted into the inner membrane from the matrix side of the membrane. GO:1901766 phosphinothricin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901766 phosphinothricin biosynthesis|phosphinothricin anabolism|phosphinothricin synthesis|phosphinothricin formation The chemical reactions and pathways resulting in the formation of phosphinothricin. GO:1901763 oxytetracycline biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901763 oxytetracycline synthesis|oxytetracycline formation|oxytetracycline biosynthesis|oxytetracycline anabolism The chemical reactions and pathways resulting in the formation of oxytetracycline. GO:0045037 protein import into chloroplast stroma biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045037 chloroplast stroma protein import|protein transport into chloroplast stroma The targeting and import of proteins into the chloroplast stroma. Import depends on ATP hydrolysis catalyzed by stromal chaperones. Chloroplast stromal proteins, such as the S subunit of rubisco, have a N-terminal stromal-import sequence of about 44 amino acids which is cleaved from the protein precursor after import. GO:0045038 protein import into chloroplast thylakoid membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045038 chloroplast thylakoid membrane protein import|protein transport into chloroplast thylakoid membrane The import of proteins into the chloroplast thylakoid membranes. Proteins that are destined for the thylakoid lumen require two uptake-targeting sequences: the first targets the protein to the stroma, and the second targets the protein from the stroma to the thylakoid lumen. Four separate thylakoid-import systems deal with the proteins once they are in the stroma. GO:1901764 phosphinothricin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901764 phosphinothricin metabolism The chemical reactions and pathways involving phosphinothricin. GO:1901761 oxytetracycline metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901761 oxytetracycline metabolism The chemical reactions and pathways involving oxytetracycline. GO:0045035 sensory organ precursor cell division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045035 sense organ precursor cell division The series of four asymmetric divisions undergone by the sensory organ precursor cells to generate cells that have distinct cell fates. For example, in the external sensory organ, the precursor cells give rise to one multidendritic neuron and four additional cells (the socket, shaft, sheath cells and the external sense neuron). GO:1901762 oxytetracycline catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901762 oxytetracycline catabolism|oxytetracycline degradation|oxytetracycline breakdown The chemical reactions and pathways resulting in the breakdown of oxytetracycline. GO:0045036 protein targeting to chloroplast biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045036 protein-chloroplast targeting The process of directing proteins towards the chloroplast, usually using signals contained within the protein. Imported proteins are synthesized as cytosolic precursors containing N-terminal uptake-targeting sequences that direct each protein to its correct subcompartment and are subsequently cleaved. GO:0060670 branching involved in labyrinthine layer morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060670 The process in which the branches of the fetal placental villi are generated and organized. The villous part of the placenta is called the labyrinth layer. GO:0045033 peroxisome inheritance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045033 The acquisition of peroxisomes by daughter cells from the mother cell after replication. In Saccharomyces cerevisiae, the number of peroxisomes cells is fairly constant; a subset of the organelles are targeted and segregated to the bud in a highly ordered, vectorial process. Efficient segregation of peroxisomes from mother to bud is dependent on the actin cytoskeleton, and active movement of peroxisomes along actin filaments is driven by the class V myosin motor protein, Myo2p. GO:1901760 beta-L-Ara4N-lipid A biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901760 4-amino-4-deoxy-beta-L-arabinose-lipid A biosynthesis|4-amino-4-deoxy-beta-L-arabinose-lipid A biosynthetic process|beta-L-Ara4N-lipid A anabolism|beta-L-Ara4N-lipid A synthesis|beta-L-Ara4N-lipid A formation|beta-L-Ara4N-lipid A biosynthesis The chemical reactions and pathways resulting in the formation of beta-L-Ara4N-lipid A which occurs as a result of modification of the lipid A moiety of lipopolysaccharide by the addition of the sugar 4-amino-4-deoxy-L-arabinose (L-Ara4N). This strategy is adopted by pathogenic Gram-negative bacteria to evade cationic antimicrobial peptides produced by the innate immune system. GO:0045034 obsolete neuroblast division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045034 neuroblast division (sensu Nematoda and Protostomia)|neuroblast division|neuroblast cell division|neuroblast division (sensu Vertebrata) OBSOLETE. The asymmetrical division of a neuroblast, the neural precursor in the central nervous system, giving rise to another neuroblast and a ganglion mother cell. GO:0060671 epithelial cell differentiation involved in embryonic placenta development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060671 The process in which a trophoblast cell acquires specialized features of an epithelial cell of the placental labyrinthine layer. GO:0060672 epithelial cell morphogenesis involved in placental branching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060672 The change in form (cell shape and size) that occurs when a trophoblast cell elongates to contribute to the branching of the placenta. GO:0060673 cell-cell signaling involved in placenta development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060673 cell-cell signalling involved in placenta development Any process that mediates the transfer of information from one cell to another. GO:0060674 placenta blood vessel development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060674 The process whose specific outcome is the progression of a blood vessel of the placenta over time, from its formation to the mature structure. GO:0060675 ureteric bud morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060675 The process in which the ureteric bud is generated and organized. GO:0060676 ureteric bud formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060676 The developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. This process begins when the bud protrudes from the duct and ends when it is a recognizable bud. GO:0060677 ureteric bud elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060677 The developmental growth in which the ureteric bud grows along its axis beginning with the growth of the primary ureteric bud and ending when the branches of the bud have elongated. GO:0060678 dichotomous subdivision of terminal units involved in ureteric bud branching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060678 bifid subdivision of terminal units involved in ureteric bud branching The process in which a ureteric bud bifurcates at its end. GO:0060679 trifid subdivision of terminal units involved in ureteric bud branching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060679 The process in which a ureteric bud splits into three units at its end. UBERON:0013161 left lateral ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013161 left telencephalic ventricle A telencephalic ventricle that is in_the_left_side_of a telencephalon. GO:0045042 obsolete protein import into mitochondrial intermembrane space, conservative biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045042 conservative protein transport into mitochondrial IMS|protein import into mitochondrial intermembrane space, conservative|conservative mitochondrial IMS protein import|protein import into mitochondrial IMS, conservative|protein transport into mitochondrial intermembrane space, conservative|conservative mitochondrial intermembrane space protein import|protein transport into mitochondrial IMS, conservative|conservative protein transport into mitochondrial intermembrane space OBSOLETE. The conservative import of proteins into the mitochondrial intermembrane space. The entire protein enters the matrix, and then the second targeting sequence directs the protein, presumably bound to a matrix protein, across the inner membrane to the intermembrane space. UBERON:0013162 right lateral ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013162 right telencephalic ventricle A telencephalic ventricle that is in_the_right_side_of a telencephalon. GO:0045043 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045043 GO:0045040 protein insertion into mitochondrial outer membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045040 protein transport into mitochondrial outer membrane|mitochondrial outer membrane protein import|protein import into mitochondrial outer membrane The process comprising the insertion of proteins from outside the organelle into the mitochondrial outer membrane, mediated by large outer membrane translocase complexes. GO:0045041 protein import into mitochondrial intermembrane space biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045041 mitochondrial intermembrane space protein import|protein import into mitochondrial IMS|protein transport into mitochondrial intermembrane space|protein import into mitochondrial intermembrane space, nonconservative|protein transport into mitochondrial IMS|protein import into mitochondrial intermembrane space, direct The import of proteins into the space between the inner and outer mitochondrial membranes. GO:1901778 pentalenolactone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901778 pentalenolactone metabolism The chemical reactions and pathways involving pentalenolactone. UBERON:0013160 epithalamus ventricular layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013160 ventricular layer epithalamus|ventricular layer of epithalamus GO:1901779 pentalenolactone catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901779 pentalenolactone breakdown|pentalenolactone catabolism|pentalenolactone degradation The chemical reactions and pathways resulting in the breakdown of pentalenolactone. GO:1901776 mitomycin C catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901776 mitomycin C degradation|mitomycin C breakdown|mitomycin C catabolism The chemical reactions and pathways resulting in the breakdown of mitomycin C. GO:1901777 mitomycin C biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901777 mitomycin C biosynthesis|mitomycin C anabolism|mitomycin C synthesis|mitomycin C formation The chemical reactions and pathways resulting in the formation of mitomycin C. GO:0045048 protein insertion into ER membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045048 protein-ER insertion|integral ER membrane protein localization|protein insertion into endoplasmic reticulum membrane|protein-endoplasmic reticulum insertion|integral ER membrane protein positioning|positioning of protein in ER membrane|localization of protein in ER membrane The process that results in incorporation of a protein into an endoplasmic reticulum (ER) membrane. It depends on specific topogenic sequences of amino acids that ensure that a protein acquires the proper orientation during its insertion into the ER membrane. GO:1901774 lincomycin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901774 lincomycin anabolism|lincomycin synthesis|lincomycin formation|lincomycin biosynthesis The chemical reactions and pathways resulting in the formation of lincomycin. GO:1901775 mitomycin C metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901775 mitomycin C metabolism The chemical reactions and pathways involving mitomycin C. GO:0045049 protein insertion into ER membrane by N-terminal cleaved signal sequence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045049 protein insertion into endoplasmic reticulum membrane by N-terminal cleaved signal sequence|protein insertion into ER membrane, N-terminal cleaved signal sequence mediated|protein-endoplasmic reticulum insertion by N-terminal cleaved signal sequence|protein-ER insertion by N-terminal cleaved signal sequence|N-terminal cleaved signal sequence mediated protein insertion into ER membrane A process of protein insertion into the endoplasmic reticulum (ER) membrane in which N-terminal cleaved signal sequences direct polypeptides to the ER. GO:1901772 lincomycin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901772 lincomycin metabolism The chemical reactions and pathways involving lincomycin. GO:0045046 protein import into peroxisome membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045046 protein transport into peroxisome membrane|peroxisome membrane protein import The targeting of proteins into the peroxisomal membrane. The process is not well understood, but both signals and mechanism differ from those involved in peroxisomal matrix protein import. GO:1901773 lincomycin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901773 lincomycin breakdown|lincomycin catabolism|lincomycin degradation The chemical reactions and pathways resulting in the breakdown of lincomycin. GO:0045047 protein targeting to ER biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045047 protein-endoplasmic reticulum targeting|protein targeting to endoplasmic reticulum|protein-ER targeting The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane. GO:1901770 daunorubicin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901770 daunorubicin degradation|daunorubicin catabolism|daunorubicin breakdown The chemical reactions and pathways resulting in the breakdown of daunorubicin. GO:0045044 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045044 GO:1901771 daunorubicin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901771 daunorubicin anabolism|daunorubicin synthesis|daunorubicin formation|daunorubicin biosynthesis The chemical reactions and pathways resulting in the formation of daunorubicin. GO:0045045 obsolete secretory pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045045 secretory pathway OBSOLETE. The pathway along which proteins and other substances are moved around and out of the cell. After synthesis on the ribosomes of the endoplasmic reticulum (ER), completed polypeptide chains are moved to the Golgi complex and subsequently sorted to various destinations. Proteins synthesized and sorted in the secretory pathway include not only those that are secreted from the cell but also enzymes and other resident proteins in the lumen of the ER, Golgi, and lysosomes as well as integral proteins in the membranes of these organelles and the plasma membrane. GO:0060660 epidermis morphogenesis involved in nipple formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060660 The process in which the epidermis of the nipple sheath is uplifted to form an umbrella-like projection. GO:0060661 submandibular salivary gland formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060661 The developmental process pertaining to the initial formation of a submandibular salivary gland. This process begins with a thickening of the epithelium next to the tongue and ends when a bud linked to the oral surface is formed. GO:1901780 pentalenolactone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901780 pentalenolactone biosynthesis|pentalenolactone anabolism|pentalenolactone synthesis|pentalenolactone formation The chemical reactions and pathways resulting in the formation of pentalenolactone. GO:0060662 salivary gland cavitation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060662 salivary gland invagination The process in which the solid core of salivary epithelium gives rise to the hollow tube of the gland. GO:0060663 apoptotic process involved in salivary gland cavitation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060663 apoptosis involved in salivary gland cavitation Any apoptotic process in which the solid core of the gland is hollowed out to form the duct. GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060664 The multiplication or reproduction of epithelial cells of the submandibular salivary gland, resulting in the expansion of a cell population and the shaping of the gland. GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signalling Any process that modulates the rate, frequency, or extent of branching involved in salivary gland morphogenesis as a result of signals being generated by the mesenchyme and received and interpreted by the salivary gland epithelium. GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060666 The process in which a salivary epithelial cord bifurcates at its end. GO:0060667 branch elongation involved in salivary gland morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060667 The differential growth of the salivary branches along their axis, resulting in the growth of a branch. GO:0060668 regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060668 regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signalling Any process that modulates the rate, frequency, or extent of salivary gland branching as a result of the transfer of information from the extracellular matrix to the epithelium of the salivary gland. GO:0060669 embryonic placenta morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060669 The process in which the embryonic placenta is generated and organized. GO:0045053 protein retention in Golgi apparatus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045053 retention of protein in Golgi|maintenance of protein location in Golgi apparatus|protein-Golgi retention The retention of proteins within the Golgi apparatus. Golgi-localized carbohydrate-modifying enzymes have a short N-terminal domain that faces the cytosol, a single transmembrane alpha helix, and a large C-terminal domain that faces the Golgi lumen and that contains the catalytic site. How the membrane-spanning alpha helix in a Golgi enzyme causes its localization and prevents its movement to the plasma membrane is not known. UBERON:0013150 future brain vesicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013150 brain vesicle|secondary brain vesicle|primary brain vesicle|primitive brain vesicle|early brain vesicle GO:0070010 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0070010 GO:0045054 constitutive secretory pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045054 constitutive exocytosis A process of exocytosis found in all eukaryotic cells, in which transport vesicles destined for the plasma membrane leave the trans-Golgi network in a steady stream. Upon exocytosis, the membrane proteins and lipids in these vesicles provide new components for the plasma membrane, and the soluble proteins inside the vesicles are released into the extracellular space. UBERON:0013151 choroidal artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013151 choroid artery|artery of choroid plexus One of two arteries (anterior and posterior choroidal artery) that supply blood to the choroid plexus, optic tract, hippocampus, globus pallidus, and other various brain regions. GO:0045051 protein insertion into ER membrane by internal uncleaved signal-anchor sequence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045051 protein insertion into ER membrane, internal uncleaved signal-anchor sequence mediated|protein-ER insertion by internal uncleaved signal-anchor sequence|internal uncleaved signal-anchor sequence mediated protein insertion into ER membrane|protein-endoplasmic reticulum insertion by internal uncleaved signal-anchor sequence|protein insertion into endoplasmic reticulum membrane by internal uncleaved signal-anchor sequence A process of protein insertion into the endoplasmic reticulum (ER) membrane in which signal anchor sequences function as both ER signal sequences and membrane anchor sequences. GO:0045052 protein insertion into ER membrane by GPI attachment sequence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045052 protein-ER insertion by GPI attachment sequence|GPI attachment sequence mediated protein insertion into ER membrane|protein-endoplasmic reticulum insertion by GPI attachment sequence|protein insertion into endoplasmic reticulum membrane by GPI attachment sequence|protein insertion into ER membrane, GPI attachment sequence mediated A process of protein insertion into the endoplasmic reticulum (ER) membrane in which proteins become anchored to the phospholipid bilayer by a covalently attached glycosylphosphatidylinositol (GPI) molecule. GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045050 protein insertion into ER membrane, stop-transfer membrane-anchor sequence mediated|protein-ER insertion by stop-transfer membrane-anchor sequence|stop-transfer membrane-anchor sequence mediated protein insertion into ER membrane|protein insertion into endoplasmic reticulum membrane by stop-transfer membrane-anchor sequence|protein-endoplasmic reticulum insertion by stop-transfer membrane-anchor sequence A process of protein insertion into the endoplasmic reticulum (ER) membrane in which stop-transfer membrane-anchor sequences become an ER membrane spanning helix. NCBITaxon:33392 Holometabola organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_33392 Endopterygota GO:1901789 benzoyl-CoA biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901789 benzoyl-CoA anabolism|benzoyl-CoA biosynthesis|benzoyl-CoA synthesis|benzoyl-CoA formation The chemical reactions and pathways resulting in the formation of benzoyl-CoA. GO:1901787 benzoyl-CoA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901787 benzoyl-CoA metabolism The chemical reactions and pathways involving benzoyl-CoA. UBERON:0013158 foregut-midgut junction gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013158 gland of foregut-midgut junction A gland that is part of a foregut-midgut junction. UBERON:0013159 epithalamus mantle layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013159 mantle layer epithalamus|mantle layer of epithalamus GO:1901788 benzoyl-CoA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901788 benzoyl-CoA degradation|benzoyl-CoA breakdown|benzoyl-CoA catabolism The chemical reactions and pathways resulting in the breakdown of benzoyl-CoA. GO:1901785 p-cresol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901785 p-cresol degradation|p-cresol catabolism|p-cresol breakdown The chemical reactions and pathways resulting in the breakdown of p-cresol. GO:0045059 positive thymic T cell selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045059 positive thymic T lymphocyte selection|positive thymic T-cell selection|positive thymic T-lymphocyte selection The process of sparing immature T cells in the thymus which react with self-MHC protein complexes with low affinity levels from apoptotic death. GO:1901786 p-cresol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901786 p-cresol anabolism|p-cresol synthesis|p-cresol formation|p-cresol biosynthesis The chemical reactions and pathways resulting in the formation of p-cresol. GO:0045057 cisternal progression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045057 cisternal maturation The process that results in the physical movement of a new cis-Golgi stack from the cis-position, nearest the endoplasmic reticulum (ER), to the trans position, farthest from the ER, successively becoming first a medial-Golgi cisterna and then a trans-Golgi cisterna. GO:1901783 p-cumate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901783 p-cumate anabolism|p-cumate synthesis|p-cumate formation|p-cumate biosynthesis The chemical reactions and pathways resulting in the formation of p-cumate. GO:0060690 epithelial cell differentiation involved in salivary gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060690 The process in which a relatively unspecialized cell acquire specialized structural and/or functional features of an epithelial cell of the salivary gland. GO:0045058 T cell selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045058 Wikipedia:Thymocyte T-cell selection|T-lymphocyte selection|T lymphocyte selection The process in which T cells that express T cell receptors that are restricted by self MHC protein complexes and tolerant to self antigens are selected for further maturation. GO:1901784 p-cresol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901784 p-cresol metabolism The chemical reactions and pathways involving p-cresol. GO:0060691 epithelial cell maturation involved in salivary gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060691 The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the salivary gland to attain its fully functional state. GO:1901781 p-cumate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901781 p-cumate metabolism The chemical reactions and pathways involving p-cumate. GO:0045055 regulated exocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045055 regulated secretory pathway A process of exocytosis in which soluble proteins and other substances are initially stored in secretory vesicles for later release. It is found mainly in cells that are specialized for secreting products such as hormones, neurotransmitters, or digestive enzymes rapidly on demand. GO:0060692 mesenchymal cell differentiation involved in salivary gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060692 The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the salivary gland. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types. UBERON:0013156 1st arch mandibular endoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013156 endoderm of mandibular component GO:0045056 transcytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045056 Wikipedia:Transcytosis The directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. GO:0060693 regulation of branching involved in salivary gland morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060693 Any process that modulates the rate, frequency, or extent of branching morphogenesis in the salivary gland epithelium. GO:1901782 p-cumate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901782 p-cumate catabolism|p-cumate degradation|p-cumate breakdown The chemical reactions and pathways resulting in the breakdown of p-cumate. GO:1901790 3-(2,3-dihydroxyphenyl)propanoate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901790 3-(2,3-dihydroxyphenyl)propanoate metabolism The chemical reactions and pathways involving 3-(2,3-dihydroxyphenyl)propanoate. GO:0060694 regulation of cholesterol transporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060694 Any process that modulates the rate, frequency, or extent of cholesterol transporter activity. GO:1901791 3-(2,3-dihydroxyphenyl)propanoate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901791 3-(2,3-dihydroxyphenyl)propanoate catabolism|3-(2,3-dihydroxyphenyl)propanoate degradation|3-(2,3-dihydroxyphenyl)propanoate breakdown The chemical reactions and pathways resulting in the breakdown of 3-(2,3-dihydroxyphenyl)propanoate. GO:0060695 negative regulation of cholesterol transporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060695 Any process that decreases the rate, frequency, or extent of cholesterol transporter activity. GO:0060696 regulation of phospholipid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060696 Any process that modulates the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester. GO:0060697 positive regulation of phospholipid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060697 Any process that increases the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester. GO:0060698 endoribonuclease inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0060698 Stops, prevents or reduces the activity of an endoribonuclease, any enzyme that catalyzes the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks. GO:0060699 regulation of endoribonuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060699 Any process that modulates the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks. GO:0070019 obsolete transforming growth factor beta type II receptor homodimeric complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070019 TGF-beta type II receptor complex|TGFBR2 homodimer|transforming growth factor beta type II receptor complex|TGF-beta type II receptor dimer OBSOLETE. A receptor complex that consists of two transforming growth factor beta (TGF-beta) type II receptor monomers. TGF-beta type II receptor dimers form in the presence or absence of ligand, and upon ligand binding can associate with TGF-beta type I receptor dimers. GO:0070017 alphav-beta3 integrin-thrombospondin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070017 ITGAV-ITGB3-THBS1 complex A protein complex that consists of an alphav-beta3 integrin complex bound to thrombospondin. GO:0070018 obsolete transforming growth factor beta type I receptor homodimeric complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070018 TGFBR1 homodimer|TGF-beta type I receptor dimer|TGF-beta type I receptor complex|transforming growth factor beta type I receptor complex OBSOLETE. A receptor complex that consists of two transforming growth factor beta (TGF-beta) type I receptor monomers. TGF-beta type I receptor dimers form in the presence or absence of ligand, and can associate with ligand-bound TGF-beta type II receptor dimers. GO:0070015 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0070015 GO:0070016 armadillo repeat domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070016 armadillo repeat binding|Arm repeat domain binding|armadillo domain binding Interacting selectively and non-covalently with the armadillo repeat domain of a protein, an approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity protein armadillo. Arm-repeat proteins are involved in various processes, including intracellular signalling and cytoskeletal regulation. GO:0070013 intracellular organelle lumen biolink:CellularComponent go-plus goslim_mouse http://purl.obolibrary.org/obo/GO_0070013 An organelle lumen that is part of an intracellular organelle. GO:0070014 sucrase-isomaltase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070014 Wikipedia:Sucrase-isomaltase oligo-1,6-glucosidase complex A protein complex that possesses oligo-1,6-glucosidase activity; the complex is a heterodimer located in the cell membrane, and is formed by proteolytic cleavage of a single precursor polypeptide. The two subunits have different substrate specificities. GO:0070011 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0070011 GO:0070012 oligopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070012 Catalysis of the hydrolysis of a peptide bond in an oligopeptide, i.e. a molecule containing a small number (2 to 20) of amino acid residues connected by peptide bonds. GO:0045064 T-helper 2 cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045064 T-helper 2 cell development The process in which a relatively unspecialized T cell acquires specialized features of a T-helper 2 (Th2) cell. A Th2 cell is a CD4-positive, alpha-beta T cell that has the phenotype GATA-3-positive and produces interleukin-4. GO:0045065 cytotoxic T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045065 cytotoxic T-lymphocyte selection|cytotoxic T lymphocyte selection|cytotoxic T cell development|cytotoxic T-cell selection The process in which a relatively unspecialized T cell acquires specialized features of a cytotoxic T cell. UBERON:0013140 systemic vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013140 systemic venous tree organ part Any vein within the general circulation that transports blood back to the right atrium of the heart. GO:0045062 extrathymic T cell selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045062 extrathymic T-cell selection|extrathymic T-lymphocyte selection|extrathymic T lymphocyte selection The process of T cell selection that occurs in extrathymic locations, often resulting T cells of distinct specificities from those selected in the thymus. GO:0045063 T-helper 1 cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045063 T-helper 1 cell development The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 1 (Th1) cell. A Th1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma. GO:0045060 negative thymic T cell selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045060 negative thymic T-cell selection|negative thymic T-lymphocyte selection|negative thymic T lymphocyte selection The process of elimination of immature T cells in the thymus which react strongly with self-antigens. GO:0045061 thymic T cell selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045061 thymic T lymphocyte selection|thymic T-cell selection|thymic T-lymphocyte selection The process of T cell selection that occurs in the thymus. GO:1901798 positive regulation of signal transduction by p53 class mediator biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901798 upregulation of signal transduction by p53 class mediator|up regulation of signal transduction by p53 class mediator|activation of signal transduction by p53 class mediator|up-regulation of signal transduction by p53 class mediator Any process that activates or increases the frequency, rate or extent of signal transduction by p53 class mediator. GO:1901799 negative regulation of proteasomal protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901799 downregulation of proteasome-mediated protein catabolism|inhibition of proteasome-mediated protein catabolic process|down-regulation of proteasomal protein catabolic process|down regulation of proteasome-mediated protein catabolism|inhibition of proteasomal protein catabolic process|down regulation of proteasome-mediated protein catabolic process|inhibition of proteasome-mediated protein catabolism|downregulation of proteasome-mediated protein catabolic process|down regulation of proteasomal protein catabolic process|down-regulation of proteasome-mediated protein catabolic process|negative regulation of proteasome-mediated protein catabolic process|down-regulation of proteasome-mediated protein catabolism|negative regulation of proteasome-mediated protein catabolism|downregulation of proteasomal protein catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of proteasomal protein catabolic process. GO:1901796 regulation of signal transduction by p53 class mediator biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901796 Any process that modulates the frequency, rate or extent of signal transduction by p53 class mediator. UBERON:0013149 hindbrain vesicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013149 rhombencephalic vesicle GO:1901797 negative regulation of signal transduction by p53 class mediator biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901797 down regulation of signal transduction by p53 class mediator|downregulation of signal transduction by p53 class mediator|down-regulation of signal transduction by p53 class mediator|inhibition of signal transduction by p53 class mediator Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction by p53 class mediator. GO:1901794 3-(3-hydroxyphenyl)propanoate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901794 3-(3-hydroxyphenyl)propanoate catabolism|3-(3-hydroxyphenyl)propanoate degradation|3-(3-hydroxyphenyl)propanoate breakdown The chemical reactions and pathways resulting in the breakdown of 3-(3-hydroxyphenyl)propanoate. GO:0045068 negative extrathymic T cell selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045068 negative extrathymic T-cell selection|negative extrathymic T-lymphocyte selection|negative extrathymic T lymphocyte selection The process of elimination of extrathymically maturing T cells which react strongly with self-antigens. GO:1901795 3-(3-hydroxyphenyl)propanoate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901795 3-(3-hydroxyphenyl)propanoate anabolism|3-(3-hydroxyphenyl)propanoate synthesis|3-(3-hydroxyphenyl)propanoate formation|3-(3-hydroxyphenyl)propanoate biosynthesis The chemical reactions and pathways resulting in the formation of 3-(3-hydroxyphenyl)propanoate. GO:0060680 lateral sprouting involved in ureteric bud morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060680 The process in which a branch forms along the side of a ureteric bud. GO:0045069 regulation of viral genome replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045069 Any process that modulates the frequency, rate or extent of viral genome replication. GO:1901792 3-(2,3-dihydroxyphenyl)propanoate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901792 3-(2,3-dihydroxyphenyl)propanoate anabolism|3-(2,3-dihydroxyphenyl)propanoate synthesis|3-(2,3-dihydroxyphenyl)propanoate formation|3-(2,3-dihydroxyphenyl)propanoate biosynthesis The chemical reactions and pathways resulting in the formation of 3-(2,3-dihydroxyphenyl)propanoate. GO:0045066 regulatory T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045066 regulatory T cell development|suppressor T cell differentiation|suppressor T lymphocyte differentiation|regulatory T lymphocyte differentiation|regulatory T-cell differentiation|suppressor T-cell differentiation|suppressor T-lymphocyte differentiation|regulatory T-lymphocyte differentiation The process in which a relatively unspecialized T cell acquires specialized features of a regulatory T cell. Regulatory T cells control or suppress immune responses through a variety of mechanisms and subsets include the CD4+CD25+ cell type as well as certain CD8+ cell types. GO:0060681 branch elongation involved in ureteric bud branching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060681 The growth of a branch of the ureteric bud along its axis. GO:1901793 3-(3-hydroxyphenyl)propanoate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901793 3-(3-hydroxyphenyl)propanoate metabolism The chemical reactions and pathways involving 3-(3-hydroxyphenyl)propanoate. GO:0060682 primary ureteric bud growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060682 The process in which the primary ureteric bud grows along its axis dorsally toward the metanephric blastema. GO:0045067 positive extrathymic T cell selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045067 positive extrathymic T-cell selection|positive extrathymic T cell selection|positive extrathymic T-lymphocyte selection|positive extrathymic T lymphocyte selection The process of sparing extrathymically maturing T cells which react with self-MHC protein complexes with low affinity levels from apoptotic death. GO:0060683 regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060683 regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signalling Any process that modulates the rate, frequency, or extent of salivary gland branching as a result of the transfer of information from the epithelial cells to the mesenchymal cells of the salivary gland. GO:0060684 epithelial-mesenchymal cell signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060684 epithelial-mesenchymal cell signalling Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted. GO:0060685 regulation of prostatic bud formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060685 Any process that modulates the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth. GO:0060686 negative regulation of prostatic bud formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060686 Any process that decreases the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth. GO:0060687 regulation of branching involved in prostate gland morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060687 Any process that modulates the rate, frequency, or extent of prostate gland branching, the process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem. GO:0060688 regulation of morphogenesis of a branching structure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060688 Any process that modulates the rate, frequency, or extent of branching morphogenesis, the process in which the anatomical structures of branches are generated and organized. GO:0070008 serine-type exopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070008 EC:3.4.21.- Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine). GO:0060689 cell differentiation involved in salivary gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060689 The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the cells of the salivary gland. GO:0070009 serine-type aminopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070009 Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine). GO:0070006 metalloaminopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070006 Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. GO:0070007 glutamic-type endopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070007 Catalysis of the hydrolysis of internal peptide bonds in a polypeptide chain by a mechanism involving a glutamate/glutamine catalytic dyad. GO:0070004 cysteine-type exopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070004 Catalysis of the hydrolysis of C- or N-terminal peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile. GO:0070005 cysteine-type aminopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070005 EC:3.4.18.- Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile. GO:0070002 glutamic-type peptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070002 Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism involving a glutamate/glutamine catalytic dyad. GO:0070003 threonine-type peptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070003 Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the hydroxyl group of a threonine residue at the active center acts as a nucleophile. GO:0070001 aspartic-type peptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070001 Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile. UBERON:0003849 mesencephalic neural crest biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003849 neural crest midbrain|mesencephalic neural crest A neural crest that has_potential_to_developmentally_contribute_to a midbrain. UBERON:0003847 thyroid artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003847 A artery that supplies a thyroid gland. UBERON:0003848 gonadal vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003848 vein of gonad|gonad vein|gonada vein|vein of gonada In medicine, gonadal vein refers to the blood vessel that carrying blood away from the gonad (testis, ovary) toward the heart. Females : ovarian vein Males : testicular vein [WP,unvetted]. UBERON:0003846 thymus epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003846 thymus gland epithelium|thymus epithelial tissue|thymic epithelial tissue|epithelial tissue of thymus gland|epithelium of thymus gland|thymic epithelium|thymus gland epithelial tissue|epithelial tissue of thymus|epithelium of thymus An epithelium that is part of a thymus, forming a supporting framework[MP,modified]. GO:0035823 short tract gene conversion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035823 A gene conversion process in which a segment of about 50-200 base pairs is transferred from the donor to the acceptor. CHEBI:131711 (S)-demethyl-4-deoxygadusol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131711 GO:0035824 long tract gene conversion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035824 A gene conversion process in which a segment of more than 1000 base pairs is transferred from the donor to the acceptor. GO:0035825 homologous recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035825 Wikipedia:Chromosomal_crossover chromosomal crossover|interstrand DNA recombination|reciprocal DNA recombination|interchromosomal DNA recombination A DNA recombination process that results in the exchange of an equal amount of genetic material between highly homologous DNA molecules. GO:0035826 obsolete rubidium ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035826 Rb+ transport|rubidium cation transport OBSOLETE. The directed movement of rubidium ions (Rb+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:61430 decanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61430 GO:0035827 obsolete rubidium ion transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035827 Rb+ transmembrane transporter activity|rubidium transmembrane transporter activity|rubidium cation transmembrane transporter activity OBSOLETE. Enables the transfer of rubidium ions (Rb+) from one side of a membrane to the other. GO:0035828 obsolete renal rubidium ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035828 renal Rb+ transport|renal rubidium cation transport OBSOLETE. The directed movement of rubidium ions (Rb+) by the kidney. GO:0035829 obsolete renal rubidium ion absorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035829 renal Rb+ absorption|renal rubidium cation absorption OBSOLETE. A renal system process in which rubidium ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures. CHEBI:131717 2-epi-valiolone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131717 CHEBI:131718 S-(1-hydroxy-2-methylbut-3-en-2-yl)glutathione(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131718 CHEBI:85400 1-heptadecanoyl-2-arachidonoyl-sn-glycero-3-phosphoserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85400 CHEBI:85401 1-heptadecanoyl-sn-glycero-3-phosphoserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85401 CHEBI:36465 cis-1,6-dihydroxycyclohexa-2,4-dienecarboxylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36465 CHEBI:85403 1-stearoyl-sn-glycero-3-phosphoserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85403 CHEBI:85404 3-dehydrocarnityl CoA(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85404 CHEBI:85405 N,N,N-trimethylglycyl-CoA(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85405 GO:0035820 negative regulation of renal sodium excretion by angiotensin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035820 The process in which angiotensin decreases the amount of sodium that is excreted in urine over a unit of time. GO:0035821 modulation of process of other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035821 regulation of physiological process of other organism|regulation of physiology of other organism|modification of morphology or physiology of other organism|regulation of morphology of other organism|regulation of morphology or physiology of other organism The process in which an organism effects a change in the structure or processes of another organism. CHEBI:85407 1-palmitoyl-sn-glycero-3-phosphoglycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85407 CHEBI:61437 fructoselysine 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61437 GO:0035822 gene conversion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035822 A DNA recombination process that results in the unidirectional transfer of genetic material from a donor sequence to a highly homologous acceptor. The resulting acceptor sequence is identical to that of the donor. CHEBI:85408 1-heptadecanoyl-2-arachidonoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85408 CHEBI:131710 S-(1-hydroxy-2-oxopropyl)-L-cysteine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131710 UBERON:0003854 spinal cord neural plate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003854 neural plate of spinal cord A neural plate that develops_from a future spinal cord. CHEBI:85409 1-heptadecanoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85409 UBERON:0003855 gonad mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003855 mesenchyme of gonad|gonada mesenchyme|mesenchyme of gonada Mesenchyme that is part of a developing gonad [Automatically generated definition]. CHEBI:36460 (E)-glutaconate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36460 UBERON:0003852 rhombencephalon neural crest biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003852 neural crest hindbrain|rhombomere neural crest|rhombencephalic neural crest A neural crest that has_potential_to_developmentally_contribute_to a hindbrain. UBERON:0003853 spinal cord neural crest biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003853 neural crest spinal cord|spinal neural crest A neural crest that has_potential_to_developmentally_contribute_to a spinal cord. UBERON:0003850 telencephalon neural crest biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003850 neural crest telencephalon A neural crest that has_potential_to_developmentally_contribute_to a telencephalon. UBERON:0003851 diencephalon neural crest biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003851 neural crest diencephalon|neural crest of future diencephalon|diencephalic neural crest|future diencephalon neural crest A neural crest that has_potential_to_developmentally_contribute_to a diencephalon. CHEBI:36464 (R)-mevalonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36464 CHEBI:36461 (E)-glutaconate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36461 CHEBI:36462 glutaconate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36462 UBERON:0003838 abdominal segment connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003838 abdominal segment of trunk portion of connective tissue|abdominal segment of trunk connective tissue|abdominal segment of trunk textus connectivus|portion of connective tissue of abdominal segment of trunk|textus connectivus of abdominal segment of trunk|connective tissue of abdominal segment of trunk A portion of connective tissue that is part of an abdominal segment of trunk [Automatically generated definition]. UBERON:0003839 forelimb joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003839 limb joint of superior member|anteriormost limb joint of limb|upper extremity joint of limb|joint of limb of forelimb|fore limb joint of limb|joint of limb of superior member|wing joint|forelimb joint of limb|limb joint of forelimb|superior member limb joint|limb joint of anteriormost limb|limb joint of upper extremity|limb joint of fore limb|joint of free upper limb|superior member joint of limb|forelimb limb joint|joint of limb of upper extremity|joint of limb of anteriormost limb|joint of limb of fore limb|fore limb limb joint|anteriormost limb limb joint|upper extremity limb joint A limb joint that is part of a forelimb [Automatically generated definition]. UBERON:0003836 abdominal segment skin biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003836 abdominal segment of trunk skin|skin of abdominal segment of trunk A skin of body that is part of an abdominal segment of trunk [Automatically generated definition]. UBERON:0003837 thoracic segment connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003837 portion of connective tissue of thorax|thorax portion of connective tissue|textus connectivus of thorax|thorax textus connectivus|upper body connective tissue|connective tissue of thorax|thorax connective tissue A portion of connective tissue that is part of a thorax [Automatically generated definition]. UBERON:0003834 thoracic segment blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003834 upper body blood vessel|blood vessel of thorax|thorax blood vessel A blood vessel that is part of a thorax [Automatically generated definition]. UBERON:0003835 abdominal segment blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003835 abdominal segment of trunk blood vessel|blood vessel of abdominal segment of trunk A blood vessel that is part of an abdominal segment of trunk [Automatically generated definition]. GO:0035812 renal sodium excretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035812 The elimination by an organism of sodium in the urine. GO:0035813 regulation of renal sodium excretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035813 Any process that modulates the amount of sodium excreted in urine over a unit of time. GO:0035814 negative regulation of renal sodium excretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035814 Any process that decreases the amount of sodium excreted in urine over a unit of time. CHEBI:131725 coproporphyrin III(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131725 GO:0035815 positive regulation of renal sodium excretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035815 natriuresis Any process that increases the amount of sodium excreted in urine over a unit of time. GO:0035816 renal water absorption involved in negative regulation of urine volume biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035816 Any process where water is taken up from the collecting ducts and proximal and distal loops of the nephron, which acts to decrease the amount of urine that is excreted from the body per unit time. CHEBI:131727 hydroxylipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131727 GO:0035817 renal sodium ion absorption involved in negative regulation of renal sodium excretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035817 Any process where sodium ions are taken up from the collecting ducts and proximal and distal loops of the nephron, which contributes to decreasing the amount of sodium that is excreted in urine per unit time. CHEBI:61442 tetrahydrofolyl-poly(glutamate) polymer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61442 GO:0035818 positive regulation of urine volume by pressure natriuresis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035818 diuresis resulting from pressure natriuresis An increase in the amount of urine excreted over a unit of time, as a result of pressure natriuresis. CHEBI:131728 [Glu(-Cys)]n-Gly(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131728 GO:0035819 positive regulation of renal sodium excretion by pressure natriuresis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035819 natriuresis resulting from pressure natriuresis An increase in the amount of sodium excreted in urine over a unit of time, as a result of pressure natriuresis. CHEBI:61440 UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-D-glucosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61440 CHEBI:61445 poly(amide) polymer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61445 CHEBI:36476 1-stearoylglycerone 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36476 CHEBI:61444 gamma-poly(glutamate) polymer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61444 CHEBI:36477 sulfoglycosphingolipid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36477 CHEBI:61449 (2E,4Z)-2-hydroxy-6-oxonona-2,4-dienedioate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61449 CHEBI:131720 (3R)-3,4-epoxy-3-methylbut-1-ene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131720 GO:0035810 positive regulation of urine volume biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035810 increase in urine flow|elevation of urinary volume|diuresis Any process that increases the amount of urine excreted from the body over a unit of time. GO:0035811 negative regulation of urine volume biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035811 decrease in urine flow|antidiuresis|reduction of urinary volume Any process that decreases the amount of urine excreted from the body over a unit of time. UBERON:0003843 dental epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003843 odontogenic epithelium|reduced enamel epithelium|dental epithelia|tooth epithelium|dental epithelium Epithelium that is part of a developing tooth or dental organ. CHEBI:36470 quinazoline alkaloid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36470 UBERON:0003841 autopod joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003841 distal free limb segment joint of limb|limb joint of distal free limb segment|paw joint|joint of limb of autopod|autopod limb joint|autopod joint of limb|joint of limb of distal free limb segment|distal free limb segment limb joint|limb joint of autopod A limb joint that is part of an autopod [Automatically generated definition]. UBERON:0003842 neural tube lumen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003842 lumen of neural tube|neurocoel|neural tube neural lumen|prosencoel|neural lumen|cavity of neural tube|central lumen An anatomical space that surrounded_by a neural tube. CHEBI:36474 drimane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36474 UBERON:0003840 hindlimb joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003840 joint of limb of inferior member|hindlimb joint of limb|limb joint of hindlimb|joint of limb of hind limb|joint of limb of lower extremity|lower extremity limb joint|joint of lower limb|hind limb limb joint|inferior member joint of limb|hind limb joint of limb|inferior member limb joint|lower extremity joint of limb|limb joint of inferior member|joint of limb of hindlimb|limb joint of hind limb|hindlimb limb joint|joint of free lower limb|limb joint of lower extremity A limb joint that is part of a hindlimb [Automatically generated definition]. CHEBI:36475 1-oleoylglycerone 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36475 CHEBI:36473 gammacerane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36473 GO:0035809 regulation of urine volume biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035809 regulation of urinary volume|regulation of urine flow Any process that modulates the amount of urine excreted from the body over a unit of time. UBERON:0003829 urethra muscle tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003829 urethral muscle layer Any muscle tissue that is part of the urethra. GO:0060809 mesodermal to mesenchymal transition involved in gastrulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060809 The epithelial to mesenchymal transition process in which a mesodermal cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell as part of the process of gastrulation. UBERON:0003827 thoracic segment bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003827 bone organ of thorax|thorax bone organ|upper body bone|bone of thorax|thorax bone A bone that is part of a thorax [Automatically generated definition]. UBERON:0003828 abdominal segment bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003828 bone of abdominal segment of trunk|abdominal segment of trunk bone organ|bone organ of abdominal segment of trunk|abdominal segment of trunk bone A bone that is part of an abdominal segment of trunk [Automatically generated definition]. UBERON:0003825 nerve of abdominal segment biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003825 abdominal segment nerve A nerve that is part of an abdominal segment of trunk [Automatically generated definition]. UBERON:0003826 upper leg bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003826 femur A bone that is part of a hindlimb stylopod [Automatically generated definition]. UBERON:0003823 hindlimb zeugopod biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003823 posterior part of leg|sura|posterior region of leg|intermediate segment of free lower limb|lower leg|regio surae|calf of leg|crus|hind limb zeudopodium|hind epipodium|hind limb middle limb segment|hindlimb zeugopod|leg|shank|posterior leg region|lower extremity middle limb segment|zeugopod of hindlimb|hindlimb epipodium|middle limb segment of hindlimb|middle limb segment of hind limb|crus of hindlimb|zeugopod of hind limb|lower extremity zeugopod|calf|regio cruris posterior|hindlimb zeudopodium|hindlimb middle limb segment|sural region|hind limb zeugopod|hindlimb zeugopodium|posterior curral region The middle limb segment of the pelvic free limb, between the autopod and stylopod segments. Includes as parts the hindlimb zeugopodial skeleton, which includes as parts the tibia and fibula, or their cartilage precursors, or evolutionary variants. UBERON:0003824 nerve of thoracic segment biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003824 thoracic segment nerve|upper body nerve|nerve of thorax|thorax nerve A nerve that is part of a thorax [Automatically generated definition]. GO:0035801 adrenal cortex development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035801 adrenal gland cortex development The process whose specific outcome is the progression of the adrenal cortex over time, from its formation to the mature structure. The adrenal cortex is located at the periphery of the adrenal gland and controls glucose and electrolyte metabolism, response to stress and sexual development through the production of different classes of steroid hormones (glucocorticoids, mineralocorticoids and androgens). GO:0035802 adrenal cortex formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035802 adrenal gland cortex formation The process that gives rise to the adrenal cortex. This process pertains to the initial formation of a structure from unspecified parts. The adrenogonadal primordium from which the adrenal cortex is formed derives from a condensation of coelomic epithelial cells (the urogenital ridge; the same structure from which gonads and kidney also originate). GO:0035803 egg coat formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035803 ZP assembly|zona pellucida assembly|vitelline envelope formation|VE formation Construction of an egg coat, a specialized extracellular matrix that surrounds the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development. GO:0035804 structural constituent of egg coat biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035804 structural constituent of vitelline envelope|structural constituent of zona pellucida The action of a molecule that contributes to the structural integrity of an egg coat. An egg coat is a specialized extracellular matrix that surrounds the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development. GO:0035805 egg coat biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035805 vitelline membrane|zona pellucida A specialized extracellular matrix that surrounds the plasma membrane of the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development. CHEBI:61452 poly(ethylene terephthalate) polymer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61452 GO:0035806 modulation of blood coagulation in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035806 modulation by organism of blood coagulation in other organism|modulation by organism of blood clotting in other organism|regulation of blood clotting in other organism|regulation of blood coagulation in other organism|regulation by organism of blood clotting in other organism Any process in which an organism modulates the frequency, rate or extent of blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot. CHEBI:85420 N-isopropyl-L-glutamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85420 GO:0035807 positive regulation of blood coagulation in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035807 positive regulation of blood clotting in other organism|positive regulation by organism of blood clotting in other organism|positive regulation by organism of blood coagulation in other organism Any process in which an organism activates, maintains or increases the frequency, rate or extent of blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot. CHEBI:61450 (2E,4Z,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61450 CHEBI:85421 N-(gamma-L-glutamyl)-L-alaninol zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85421 CHEBI:61451 (E)-3-[(5S,6R)-5,6-dihydroxycyclohexa-1,3-dienyl]acrylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61451 CHEBI:85422 (S)-2-aminopropan-1-ol(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85422 GO:0035808 meiotic recombination initiation complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035808 A protein complex that initiates the formation of double-strand breaks (DSBs) required for meiotic recombination. Consists of a protein that catalyses formation of the double-strand breaks (Spo11 in S. cerevisiae and Rec12 in S. pombe), and a number of accessory proteins. CHEBI:36445 alkylglucosinolate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36445 CHEBI:61457 UDP-beta-L-arabinopyranose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61457 CHEBI:85424 glycine transporter 2 inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85424 CHEBI:61454 GDP-beta-L-galactose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61454 CHEBI:85425 glycine transporter inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85425 CHEBI:85426 3-phenylpropionitrile biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85426 CHEBI:61455 UDP-beta-L-arabinopyranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61455 CHEBI:85427 1,2-dipalmitoyl-3-palmitoleoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85427 CHEBI:85428 trans-3-hydroxy-L-proline residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85428 CHEBI:85429 phosphatidylethanol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85429 GO:0060810 intracellular mRNA localization involved in pattern specification process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060810 intracellular mRNA localisation involved in pattern specification process Any process in which mRNA is transported to, or maintained in, a specific location within an oocyte that results in a pattern being established in the embryo. GO:0060811 intracellular mRNA localization involved in anterior/posterior axis specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060811 intracellular mRNA localisation involved in anterior/posterior axis specification Any process in which mRNA is transported to, or maintained in, a specific location within the oocyte and/or syncytial embryo that contributes to the specification of the anterior/posterior axis. GO:0035800 deubiquitinase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035800 Increases the activity of deubiquitinase, an enzyme that catalyzes the hydrolysis of various forms of polymeric ubiquitin sequences. UBERON:0003832 esophagus muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003832 esophageal muscle|muscle organ of oesophagus|oesophagus muscle organ|muscle organ of esophagus|muscle organ of gullet|gullet muscle organ|esophagus muscle organ Any muscle organ that is part of a esophagus [Automatically generated definition]. GO:0060812 orthodenticle mRNA localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060812 orthodenticle mRNA localisation Any process in which orthodenticle mRNA is transported to and maintained in the oocyte and/or syncytial embryo as part of the process that will specify the anterior/posterior axis. UBERON:0003833 abdominal segment muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003833 abdominal segment of trunk muscle organ|muscle organ of abdominal segment of trunk A muscle organ that is part of an abdominal segment of trunk [Automatically generated definition]. GO:0060813 anterior mRNA localization involved in anterior/posterior axis specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060813 anterior mRNA localisation involved in anterior/posterior axis specification Any process in which a mRNA is transported to, and maintained in the anterior portion of the oocyte and/or syncytial embryo contributing to the specification of the anterior/posterior axis. GO:0060814 posterior mRNA localization involved in anterior/posterior axis specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060814 posterior mRNA localisation involved in anterior/posterior axis specification Any process in which a mRNA is transported to and maintained in the oocyte and/or syncytial embryo contributing to the specification of the anterior/posterior axis. UBERON:0003830 thoracic segment muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003830 muscle organ of thorax|thorax muscle organ|upper body muscle Any muscle organ that is part of a thorax [Automatically generated definition]. UBERON:0003831 respiratory system muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003831 respiratory system muscle organ|muscle organ of respiratory system|muscle organ of apparatus respiratorius|apparatus respiratorius muscle organ Any muscle organ that is part of a respiratory system [Automatically generated definition]. GO:0060815 regulation of translation involved in anterior/posterior axis specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060815 Any process that modulates the frequency, rate or extent of translation of mRNAs that contribute to the specification of the anterior/posterior axis. GO:0060816 random inactivation of X chromosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060816 Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on either the paternal or maternal X-chromosome in the XX sex. GO:0060817 inactivation of paternal X chromosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060817 Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes specifically on the paternal X-chromosome in the XX sex. GO:0060818 inactivation of paternal X chromosome by genetic imprinting biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060818 Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on the paternal X-chromosome in the XX sex by genetic imprinting. GO:0060819 inactivation of X chromosome by genetic imprinting biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060819 Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by genetic imprinting. CHEBI:131708 N(omega)-(1-hydroxy-2-oxopropyl)-L-arginine residue(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131708 CHEBI:131709 N(6)-(1-hydroxy-2-oxopropyl)-L-lysine residue(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131709 CHEBI:131701 poly(ethylene terephthalate)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131701 CHEBI:61460 UDP-beta-L-arabinofuranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61460 CHEBI:131702 stigmastane derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131702 CHEBI:131703 stigmastane sterol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131703 CHEBI:131704 4-[(2-hydroxyethoxy)carbonyl]benzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131704 CHEBI:61463 UDP-beta-L-arabinofuranose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61463 CHEBI:131705 2'-deoxynucleoside 3'-monophosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131705 CHEBI:131706 (2Z,4S,5R)-2-amino-4,5,6-trihydroxyhex-2-enoic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131706 CHEBI:131707 (4S,5R)-4,5,6-trihydroxy-2-iminohexanoic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131707 CHEBI:85411 sn-glycero-3-phosphoglycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85411 CHEBI:61462 (E)-3-[(5S,6R)-5,6-dihydroxycyclohexa-1,3-dienyl]acrylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61462 CHEBI:85412 mitomycin A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85412 CHEBI:36456 homoisocitrate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36456 CHEBI:61467 (2E,4Z,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61467 CHEBI:85413 5-hydroxyectoine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85413 CHEBI:36457 homocitrate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36457 CHEBI:85414 (6S)-5,6,7,8-tetrahydropteroate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85414 CHEBI:36454 isocitrate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36454 CHEBI:85415 (Z)-hex-3-enoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85415 CHEBI:36455 homoisocitrate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36455 CHEBI:85416 mitomycin B biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85416 CHEBI:85417 dTDP-beta-L-daunosamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85417 CHEBI:36458 homocitrate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36458 CHEBI:85418 7-demethylmitomycin B biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85418 CHEBI:61469 polyanionic polymer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61469 GO:0060800 regulation of cell differentiation involved in embryonic placenta development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060800 Any process that modulates the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state. CHEBI:36459 homocitrate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36459 CHEBI:85419 7-demethylmitomycin A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85419 UBERON:0003821 metapodium bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003821 metapodial bone|metacarpal/metatarsal bone|metapodium bone|metacarpal/metatarsal|metacarpal or metatarsal bone|metapodi bone A bone of the metapodial skeleton GO:0060801 negative regulation of trophoblast cell differentiation by transforming growth factor beta signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060801 negative regulation of trophoblast cell differentiation by transforming growth factor beta signalling pathway The transforming growth factor signaling process that decreases the rate, frequency, or extent of trophoblast stem cells differentiating into the more mature cells of the trophoblast. UBERON:0003822 forelimb stylopod biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003822 proximal segment of free upper limb|regio brachialis|brachium|stylopod of arm|fore propodium|forelimb stylopodium|wing stylopod|stylopod of forelimb|upper arm|arm|forelimb propodium|brachial region|forelimb stylopodial element The part of the forelimb between pectoral region and the elbow, corresponding to the humerus. GO:0060802 epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060802 epiblast cell-extraembryonic ectoderm cell signalling involved in anterior/posterior axis specification Any process that mediates the transfer of information from an epiblast cell to an extraembryonic ectoderm cell that contributes to the specification of the anterior/posterior axis. GO:0060803 BMP signaling pathway involved in mesodermal cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060803 BMP signalling pathway involved in mesodermal cell fate specification A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to a cell becoming specified to adopt a mesodermal fate. GO:0060804 positive regulation of Wnt signaling pathway by BMP signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060804 positive regulation of WNT receptor signaling pathway by BMP signaling pathway|positive regulation of Wnt-activated signaling pathway by BMP signaling pathway|positive regulation of Wnt receptor signaling pathway by BMP signaling pathway|positive regulation of WNT receptor signalling pathway by BMP signalling pathway A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that results in an increase in the rate, frequency or extent of a Wnt signaling pathway. UBERON:0003820 prostate bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003820 prostatic bud|prostate ductal progenitor|prostate gland bud|prostate primordium A region of the fetal urogenital sinus epithelium destined to become the prostate[GO]. GO:0060805 negative regulation of trophoblast cell differentiation by transcription regulation from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060805 Any process that modulates the rate, frequency or extent of transcription from an RNA polymerase II promoter ultimately resulting in a decrease in trophoblast stem cells differentiating into the more mature cells of the trophoblast. CHEBI:36452 aralkylglucosinolate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36452 GO:0060806 negative regulation of cell differentiation involved in embryonic placenta development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060806 Any process that decreases the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state. CHEBI:36453 isocitrate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36453 GO:0060807 obsolete regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060807 OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that ultimately results in a cell being specified to adopt a definitive endodermal cell fate. CHEBI:36451 alkenylglucosinolate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36451 GO:0060808 positive regulation of mesodermal to mesenchymal transition involved in gastrulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060808 Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where a mesodermal cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell as part of the process of gastrulation. UBERON:0003889 fallopian tube biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003889 tuba uterina|paramesonephric duct of female|female paramesonephric duct|fallopian tubes|mammalian oviduct|uterine tube (sensu Mammalia)|salpinx|salpinges Initial section of the oviduct through which the ova pass from the ovary to the uterus CHEBI:61470 (2E,4Z)-2-hydroxy-6-oxonona-2,4-dienedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61470 CHEBI:85440 very long-chain (R)-3-hydroxyacyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85440 CHEBI:85442 trans-3-hexenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85442 CHEBI:61472 all-trans-6-methoxy-2-hexaprenylhydroquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61472 CHEBI:85443 (3E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85443 CHEBI:61473 all-trans-5-methoxy-2-methyl-3-hexaprenylhydroquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61473 CHEBI:61478 germacrene C biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61478 CHEBI:36423 1H-carbazole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36423 CHEBI:85445 2'-deoxyguanosine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85445 UBERON:0003890 Mullerian duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003890 Müllerian duct|ductus paramesonephricus|early paramesonephric duct|paramesonephric duct|Muellerian duct paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin[WP]. develops either by lengthwise splitting of the archinephric duct (in chondrichthyans and some amphibians) or by a elongated invagination of the coelomic epithelium (other vertebrates) In males, the oviducts regress. The cranial end of the oviduct maintains an opening into the coelom (which primitively may have been the anteriormost coelomic funnels connecting the nephrocoel with the coelom). This opening is the ostium tubae[USM]. UBERON:0003891 stroma biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003891 stromal connective tissue Connective, non-functional supportive framework of a biological cell, tissue, or organ. Contrast with parenchyma. CHEBI:36424 4aH-carbazole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36424 CHEBI:36422 3H-carbazole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36422 CHEBI:85448 6-O-methyl dGMP(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85448 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060830 ciliary receptor clustering involved in smoothened signalling pathway|ciliary receptor clustering involved in hh signaling pathway|ciliary receptor clustering involved in hedgehog signaling pathway Grouping of smoothened or patched receptors in a cilium, contributing to the smoothened signaling pathway. CHEBI:85449 O-tetradecenoyl-L-carnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85449 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060831 hh signaling pathway involved in dorsal/ventral neural tube patterning|hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|smoothened signalling pathway involved in dorsal/ventral neural tube patterning The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened contributing to the dorsal/ventral pattern of the neural tube. CHEBI:36425 8aH-carbazole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36425 GO:0060832 oocyte animal/vegetal axis specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060832 The establishment, maintenance and elaboration of the animal/vegetal axis in the oocyte. The animal/vegetal axis of an oocyte is defined by the placement of the nucleus in the oocyte and can sometimes be identified by the asymmetric placement of other substances such as yolk in the oocyte. The pole of the egg that is closest to the nucleus defines the animal end, with the axis passing through the nucleus. GO:0060833 Wnt signaling pathway involved in animal/vegetal axis specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060833 Wnt- activated signaling pathway involved in animal/vegetal axis specification|Wnt receptor signalling pathway involved in animal/vegetal axis specification|Wnt receptor signaling pathway involved in animal/vegetal axis specification The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell contributing to the specification of the animal/vegetal axis of an oocyte. UBERON:0003898 skeletal muscle tissue of trunk biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003898 skeletal muscle of torso|trunk skeletal muscle|torso skeletal muscle|skeletal muscle tissue of trunk|skeletal muscle tissue of torso|torso skeletal muscle tissue|trunk skeletal muscle tissue A portion of skeletal muscle tissue in the trunk. GO:0060834 oral/aboral axis specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060834 oral/aboral axis determination The establishment, maintenance and elaboration of a line that delineates the mouth and the anus of an embryo. GO:0060835 transforming growth factor receptor beta signaling pathway involved in oral/aboral axis specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060835 transforming growth factor receptor beta signalling pathway involved in oral/aboral axis specification A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to the specification of the oral/aboral axis. GO:0060836 lymphatic endothelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060836 The process in which a venous blood vessel endothelial cell acquires specialized features of a lymphatic vessel endothelial cell, a thin flattened cell that lines the inside surfaces of lymph vessels. GO:0060837 blood vessel endothelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060837 The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell, a thin flattened cell that lines the inside surfaces of blood vessels. UBERON:0003897 axial muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003897 One of the skeletal muscles of the head and neck, spine, and ribs. GO:0060838 lymphatic endothelial cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060838 The commitment of a venous blood vessel endothelial cell to a lymphatic endothelial cell fate and its capacity to differentiate into a lymphatic endothelial cell. UBERON:0003894 liver primordium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003894 liver bud|hepatic plate|embryological hepatic plate|primordium of the liver|liver endoderm A small endodermal thickening in the foregut adjacent to the transverse septum. Invaginates forming the hepatic diverticulum. GO:0060839 endothelial cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060839 The commitment of a cell to an endothelial cell fate and its capacity to differentiate into an endothelial cell. CHEBI:36420 acridine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36420 UBERON:0003893 capsule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003893 A cover or envelope partly or wholly surrounding a structure. Examples: egg shell, articular capsules, renal capsules[WP]. GO:0045204 MAPK export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045204 cytoplasmic translocation of MAP kinase|cytoplasmic translocation of mitogen-activated protein kinase|MAPK export from cell nucleus|MAPK transport from nucleus to cytoplasm|MAPK-nucleus export|MAPK export out of nucleus The directed movement of a MAP kinase from the nucleus to the cytoplasm. CHEBI:61481 dCTP(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61481 GO:0045205 obsolete MAPK transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045205 MAPK transporter activity OBSOLETE. Enables the directed movement of MAP kinase into, out of or within a cell, or between cells. GO:0045202 synapse biolink:CellularComponent go-plus goslim_mouse|goslim_agr|goslim_synapse|goslim_pir|goslim_drosophila|goslim_flybase_ribbon http://purl.obolibrary.org/obo/GO_0045202 NIF_Subcellular:sao914572699|Wikipedia:Chemical_synapse electrotonic synapse|synaptic junction|mixed synapse The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane. GO:0045203 integral component of cell outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045203 integral to external membrane|integral to cell outer membrane|integral to outer membrane The component of the cell outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0045200 establishment of neuroblast polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045200 establishment of neuroblast cell polarity The specification and formation of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system. CHEBI:85430 11-deoxy-beta-rhodomycin zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85430 GO:0045201 maintenance of neuroblast polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045201 maintenance of neuroblast cell polarity The maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system. CHEBI:85433 glutamine hydroxamate zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85433 CHEBI:36434 octadecatrienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36434 CHEBI:36432 2-methylbut-2-enoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36432 CHEBI:36438 (9Z,13S,15Z)-12,13-epoxyoctadeca-9,11,15-trienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36438 GO:0045208 MAPK phosphatase export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045208 MAPK phosphatase-nucleus export|MAPK phosphatase transport from nucleus to cytoplasm|MAPK phosphatase export from cell nucleus|MAPK phosphatase export out of nucleus The directed movement of a MAPK phosphatase from the nucleus to the cytoplasm. GO:0045209 MAPK phosphatase export from nucleus, leptomycin B sensitive biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045209 leptomycin B-sensitive MAPK phosphatase export out of nucleus|MAPK phosphatase-nucleus export, leptomycin B sensitive|leptomycin B-sensitive MAPK phosphatase-nucleus export|MAPK phosphatase transport from nucleus to cytoplasm, leptomycin B sensitive|leptomycin B-sensitive MAPK phosphatase transport from nucleus to cytoplasm|MAPK phosphatase export from cell nucleus, leptomycin B sensitive|MAPK phosphatase export out of nucleus, leptomycin B sensitive Leptomycin B-sensitive movement of a MAPK phosphatase from the nucleus to the cytoplasm. GO:0060820 inactivation of X chromosome by heterochromatin assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060820 inactivation of X chromosome by heterochromatin formation Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by the mechanism of heterochromatin formation. CHEBI:85439 trans,trans-2,4-hexadienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85439 GO:0060821 inactivation of X chromosome by DNA methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060821 Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by a mechanism of DNA methylation. GO:0045206 obsolete MAPK phosphatase transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045206 MKP shuttle|leptomycin B-sensitive MKP shuttle|MAPK phosphatase transporter activity|leptomycin B-sensitive MAPK phosphatase transporter activity OBSOLETE. Enables the directed movement of MAPK phosphatase into, out of or within a cell, or between cells. GO:0060822 transforming growth factor beta receptor signaling pathway involved in axial mesodermal cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060822 transforming growth factor beta receptor signalling pathway involved in axial mesodermal cell fate specification The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands and ultimately resulting in the specification of an axial mesodermal fate. GO:0045207 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045207 GO:0060823 canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060823 canonical Wnt receptor signalling pathway involved in neural plate anterior/posterior pattern formation|canonical Wnt-activated signaling pathway involved in neural plate anterior/posterior pattern formation|canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation|Wnt receptor signaling pathway through beta-catenin involved in neural plate anterior/posterior pattern formation The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the formation of the neural plate anterior/posterior pattern. UBERON:0003887 intraembryonic coelom biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003887 somatic coelom The part of the coelom in the embryo between the somatopleuric and splanchnopleuric mesoderm; the principal body cavities of the trunk (thoracic, abdominal, and pelvic) arise from this embryonic part of the coelom GO:0060824 retinoic acid receptor signaling pathway involved in neural plate anterior/posterior pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060824 retinoic acid receptor signalling pathway involved in neural plate anterior/posterior pattern formation The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that contributes to the formation of the anterior/posterior pattern of the neural plate. GO:0060825 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060825 fibroblast growth factor receptor signalling pathway involved in neural plate anterior/posterior pattern formation The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands contributing to the anterior/posterior pattern of the neural plate. UBERON:0003885 mesometrium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003885 mesentery of uterus A mesentery that is part of a uterus [Automatically generated definition]. UBERON:0003886 future coelemic cavity lumen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003886 body cavity precursor An anatomical cavity that has the potential to develop into a coelemic cavity lumen. GO:0060826 transforming growth factor beta receptor signaling pathway involved in neural plate anterior/posterior pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060826 transforming growth factor beta receptor signalling pathway involved in neural plate anterior/posterior pattern formation A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to the formation of the neural plate anterior/posterior pattern. GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060827 regulation of canonical Wnt-activated signaling pathway involved in neural plate anterior/posterior pattern formation|regulation of Wnt receptor signaling pathway through beta-catenin involved in neural plate anterior/posterior pattern formation|regulation of canonical Wnt receptor signalling pathway involved in neural plate anterior/posterior pattern formation|regulation of canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation Any process that modulates the rate, frequency, or extent of Wnt signaling through beta-catenin that results in the formation of the neural plate anterior/posterior pattern. GO:0060828 regulation of canonical Wnt signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060828 regulation of canonical Wnt receptor signalling pathway|regulation of catenin import into nucleus|regulation of canonical Wnt receptor signaling pathway|regulation of canonical Wnt-activated signaling pathway|regulation of catenin protein nuclear translocation|catenin import into nucleus|regulation of Wnt receptor signaling pathway through beta-catenin Any process that modulates the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060829 negative regulation of canonical Wnt-activated signaling pathway involved in neural plate anterior/posterior pattern|negative regulation of canonical Wnt receptor signalling pathway involved in neural plate anterior/posterior pattern formation|negative regulation of canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern|negative regulation of Wnt receptor signaling pathway through beta-catenin involved in neural plate anterior/posterior pattern formation Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin in the anterior end of the neural plate. This regulation sets up a Wnt signaling gradient along the anterior/posterior axis. GO:1901707 leptomycin B binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901707 Interacting selectively and non-covalently with leptomycin B. GO:1901708 (+)-3'-hydroxylarreatricin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901708 (+)-3'-hydroxylarreatricin synthesis|(+)-3'-hydroxylarreatricin biosynthesis|(+)-3'-hydroxylarreatricin formation|(+)-3'-hydroxylarreatricin anabolism The chemical reactions and pathways resulting in the formation of (+)-3'-hydroxylarreatricin. GO:1901705 L-isoleucine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901705 L-isoleucine biosynthesis|L-isoleucine anabolism|L-isoleucine synthesis|L-isoleucine formation The chemical reactions and pathways resulting in the formation of L-isoleucine. GO:1901706 mesenchymal cell differentiation involved in bone development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901706 The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of bone as it progresses from its formation to the mature state. GO:1901703 protein localization involved in auxin polar transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901703 establishment and maintenance of protein localization involved in auxin polar transport|protein localisation involved in auxin polar transport Any protein localization that is involved in auxin polar transport. UBERON:0003869 presumptive ganglion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003869 A presumptive structure that has the potential to develop into a ganglion. GO:1901704 L-glutamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901704 L-glutamine formation|L-glutamine biosynthesis|L-glutamine anabolism|L-glutamine synthesis The chemical reactions and pathways resulting in the formation of L-glutamine. GO:1901701 cellular response to oxygen-containing compound biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901701 cellular response to oxygen molecular entity Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus. UBERON:0003867 distal phalanx of pes biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003867 ungual phalanx of hindlimb|phalanx distalis pedis|foot distal phalanx|distal phalanx of toe|terminal phalanx of foot|terminal phalanx of hindlimb|distal pedal phalanx|ungual phalanx of foot|distal phalanx of foot A distal phalanx that is part of a pedal digit [Automatically generated definition]. UBERON:0003868 proximal phalanx of pes biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003868 proximal phalanx of foot digit|proximal phalanx of toe|proximal pedal phalanx|proximal phalanx of foot|phalanx proximalis pedis|foot proximal phalanx|proximal phalanx of pes|proximal phalanx of hind digit A proximal phalanx that is part of a pedal digit [Automatically generated definition]. GO:1901702 salt transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901702 Enables the transfer of salt from one side of a membrane to the other. GO:0045215 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045215 GO:1901700 response to oxygen-containing compound biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901700 response to oxygen molecular entity Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus. GO:0045216 cell-cell junction organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045216 intercellular junction assembly and maintenance|cell-cell junction biogenesis|cell-cell junction organisation|cell-cell junction assembly and maintenance A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-cell junction. A cell-cell junction is a specialized region of connection between two cells. GO:0045213 neurotransmitter receptor metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045213 neurotransmitter receptor metabolism The chemical reactions and pathways involving neurotransmitter receptors. GO:0045214 sarcomere organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045214 sarcomere organisation|sarcomere alignment The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs. CHEBI:36408 5-hydroxy-L-kynurenine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36408 CHEBI:61496 alpha-D-FucNAc4-(1->4)-beta-D-ManNAcA-(1->4)-D-GlcNAc-undecaprenyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61496 GO:0045211 postsynaptic membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0045211 post-synaptic membrane A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane. GO:0045212 obsolete neurotransmitter receptor biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045212 neurotransmitter receptor anabolism|neurotransmitter receptor synthesis|neurotransmitter receptor formation|neurotransmitter receptor biosynthesis OBSOLETE. The chemical reactions and pathways resulting in the formation of neurotransmitter receptors. CHEBI:61494 UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-N-acetylglucosamine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61494 CHEBI:61495 beta-D-ManNAcA-(1->4)-alpha-D-GlcNAc-1-diphospho-ditrans,polycis-undecaprenol(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61495 GO:0045210 FasL biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045210 fas ligand biosynthetic process|FasL biosynthesis|APT1LG1 biosynthetic process|CD95L biosynthesis|CD95L biosynthetic process|FasL anabolism|CD178 biosynthetic process|FASLG biosynthetic process|FasL synthesis|FasL formation|Fas-L biosynthetic process The chemical reactions and pathways resulting in the formation of fas ligand (FasL or CD95L), an antigen originally found to be expressed on the cell surface of activated human T-lymphocytes and B-lymphocytes and a variety of malignant human lymphoid cell lines. CHEBI:36401 cycloalkadiene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36401 CHEBI:85468 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4-phosphate)(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85468 CHEBI:36402 cycloalkatriene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36402 GO:0060850 obsolete regulation of transcription involved in cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060850 OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a cell to a specific fate. CHEBI:61498 epoxy fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61498 GO:0060851 vascular endothelial growth factor receptor signaling pathway involved in lymphatic endothelial cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060851 vascular endothelial growth factor receptor signalling pathway involved in lymphatic endothelial cell fate commitment The series of molecular signals generated as a consequence of vascular endothelial growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a venous endothelial cell to a lymphatic endothelial cell fate. CHEBI:36405 2-aminohexanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36405 GO:0045219 regulation of FasL production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045219 regulation of FasL biosynthesis|regulation of FasL anabolism|regulation of FasL synthesis|regulation of FasL formation Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of FasL. GO:0060852 obsolete regulation of transcription involved in venous endothelial cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060852 OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a cell to a specific fate and contributes to a cell adopting a venous endothelial cell fate. GO:0060853 Notch signaling pathway involved in arterial endothelial cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060853 Notch signalling pathway involved in arterial endothelial cell fate commitment The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell and contributing to the commitment of a cell to an arterial endothelial cell fate. GO:0045217 cell-cell junction maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045217 intercellular junction maintenance The maintenance of junctions between cells. GO:0060854 branching involved in lymph vessel morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060854 patterning of lymph vessels The process of the coordinated growth and sprouting of lymph vessels giving rise to the organized lymphatic system. CHEBI:36403 monocyclic olefin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36403 GO:0045218 zonula adherens maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045218 Maintaining the zonula adherens junction, the cell-cell adherens junction formed near the apex of epithelial cells. GO:0060855 venous endothelial cell migration involved in lymph vessel development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060855 The orderly movement of venous endothelial cells out of the veins giving rise to the precursors of lymphatic endothelial cells. CHEBI:36404 cyclohexene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36404 GO:0060856 establishment of blood-brain barrier biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060856 establishment of blood/brain barrier|establishment of BBB Establishment of the barrier between the blood and the brain. The cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier. GO:0060857 establishment of glial blood-brain barrier biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060857 establishment of glial BBB|establishment of glial blood/brain barrier Establishment of the glial barrier between the blood and the brain. The glial cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier. GO:0060858 vesicle-mediated transport involved in floral organ abscission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060858 membrane trafficking involved in floral organ shedding The directed movement of substances within a cell by a cellular process that begins with the formation of membrane-bounded vesicles in which the transported substances are enclosed or located in the vesicle membrane which are then targeted to, and fuse with, an acceptor membrane contributing to the shedding of a floral organ. GO:0060859 obsolete regulation of vesicle-mediated transport involved in floral organ abscission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060859 OBSOLETE. Any process that modulates the rate, frequency, or extent of the directed movement of substances within a cell by a cellular process that begins with the formation of membrane-bounded vesicles in which the transported substances are enclosed or located in the vesicle membrane which are then targeted to, and fuse with, an acceptor membrane contributing to the shedding of a floral organ. GO:1901709 (+)-larreatricin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901709 (+)-larreatricin metabolism The chemical reactions and pathways involving (+)-larreatricin. GO:1901718 obsolete regulation of dipeptide transmembrane transport by regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901718 OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of dipeptide transmembrane transport. GO:1901719 regulation of NMS complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901719 regulation of KMN network assembly involved in chromosome segregation|regulation of NMS complex association involved in chromosome segregation|regulation of NMS complex assembly involved in kinetochore assembly|regulation of KMN complex assembly involved in chromosome segregation Any process that modulates the frequency, rate or extent of NMS complex assembly. The NMS complex is involved in chromosome segregation. GO:1901716 negative regulation of gamma-aminobutyric acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901716 downregulation of 4-aminobutanoate catabolism|downregulation of gamma-aminobutyric acid breakdown|down regulation of gamma-aminobutyric acid catabolic process|inhibition of GABA catabolism|down-regulation of gamma-aminobutyric acid catabolism|negative regulation of gamma-aminobutyric acid catabolism|downregulation of GABA catabolic process|down regulation of 4-aminobutyrate catabolic process|down-regulation of gamma-aminobutyric acid degradation|negative regulation of gamma-aminobutyric acid degradation|downregulation of gamma-aminobutyric acid catabolic process|downregulation of 4-aminobutyrate catabolism|negative regulation of 4-aminobutanoate catabolic process|down regulation of GABA catabolic process|down-regulation of 4-aminobutanoate catabolic process|down regulation of GABA catabolism|negative regulation of 4-aminobutanoate catabolism|downregulation of 4-aminobutyrate catabolic process|down-regulation of 4-aminobutanoate catabolism|down-regulation of gamma-aminobutyric acid breakdown|negative regulation of gamma-aminobutyric acid breakdown|down regulation of 4-aminobutyrate catabolism|downregulation of gamma-aminobutyric acid catabolism|downregulation of GABA catabolism|inhibition of GABA catabolic process|down-regulation of gamma-aminobutyric acid catabolic process|down regulation of gamma-aminobutyric acid catabolism|downregulation of 4-aminobutanoate catabolic process|inhibition of gamma-aminobutyric acid degradation|negative regulation of 4-aminobutyrate catabolic process|inhibition of 4-aminobutyrate catabolism|down-regulation of 4-aminobutyrate catabolic process|down regulation of 4-aminobutanoate catabolic process|inhibition of gamma-aminobutyric acid catabolic process|inhibition of 4-aminobutanoate catabolism|inhibition of gamma-aminobutyric acid breakdown|negative regulation of GABA catabolism|inhibition of gamma-aminobutyric acid catabolism|down-regulation of GABA catabolism|down regulation of gamma-aminobutyric acid degradation|negative regulation of GABA catabolic process|down-regulation of GABA catabolic process|inhibition of 4-aminobutanoate catabolic process|down regulation of 4-aminobutanoate catabolism|downregulation of gamma-aminobutyric acid degradation|down regulation of gamma-aminobutyric acid breakdown|down-regulation of 4-aminobutyrate catabolism|inhibition of 4-aminobutyrate catabolic process|negative regulation of 4-aminobutyrate catabolism Any process that stops, prevents or reduces the frequency, rate or extent of gamma-aminobutyric acid catabolic process. GO:1901717 positive regulation of gamma-aminobutyric acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901717 positive regulation of GABA catabolic process|upregulation of gamma-aminobutyric acid catabolic process|up regulation of gamma-aminobutyric acid degradation|up-regulation of 4-aminobutanoate catabolic process|up regulation of GABA catabolic process|activation of gamma-aminobutyric acid catabolism|positive regulation of gamma-aminobutyric acid degradation|upregulation of 4-aminobutyrate catabolic process|positive regulation of 4-aminobutyrate catabolism|up regulation of 4-aminobutanoate catabolism|up regulation of 4-aminobutyrate catabolism|up regulation of gamma-aminobutyric acid breakdown|positive regulation of 4-aminobutanoate catabolism|upregulation of GABA catabolism|activation of gamma-aminobutyric acid degradation|activation of 4-aminobutanoate catabolic process|positive regulation of gamma-aminobutyric acid catabolism|positive regulation of gamma-aminobutyric acid breakdown|up regulation of gamma-aminobutyric acid catabolic process|up regulation of gamma-aminobutyric acid catabolism|activation of gamma-aminobutyric acid catabolic process|upregulation of GABA catabolic process|activation of 4-aminobutanoate catabolism|activation of gamma-aminobutyric acid breakdown|positive regulation of 4-aminobutanoate catabolic process|up-regulation of gamma-aminobutyric acid degradation|up regulation of 4-aminobutyrate catabolic process|up regulation of 4-aminobutanoate catabolic process|positive regulation of 4-aminobutyrate catabolic process|upregulation of 4-aminobutyrate catabolism|up regulation of GABA catabolism|up-regulation of 4-aminobutanoate catabolism|up-regulation of gamma-aminobutyric acid breakdown|positive regulation of GABA catabolism|upregulation of gamma-aminobutyric acid catabolism|activation of 4-aminobutyrate catabolic process|up-regulation of GABA catabolic process|up-regulation of gamma-aminobutyric acid catabolic process|upregulation of gamma-aminobutyric acid degradation|upregulation of 4-aminobutanoate catabolic process|up-regulation of 4-aminobutyrate catabolism|activation of GABA catabolism|up-regulation of 4-aminobutyrate catabolic process|activation of GABA catabolic process|upregulation of 4-aminobutanoate catabolism|upregulation of gamma-aminobutyric acid breakdown|up-regulation of gamma-aminobutyric acid catabolism|activation of 4-aminobutyrate catabolism|up-regulation of GABA catabolism Any process that activates or increases the frequency, rate or extent of gamma-aminobutyric acid catabolic process. GO:1901714 positive regulation of urea catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901714 up regulation of urea catabolic process|upregulation of urea degradation|upregulation of urea catabolism|upregulation of urea breakdown|up-regulation of urea decomposition|upregulation of urea catabolic process|up-regulation of urea degradation|activation of urea decomposition|up-regulation of urea breakdown|up regulation of urea catabolism|activation of urea degradation|positive regulation of urea decomposition|positive regulation of urea catabolism|up-regulation of urea catabolic process|up regulation of urea decomposition|activation of urea catabolic process|positive regulation of urea degradation|activation of urea breakdown|up regulation of urea degradation|activation of urea catabolism|positive regulation of urea breakdown|up regulation of urea breakdown|up-regulation of urea catabolism|upregulation of urea decomposition Any process that activates or increases the frequency, rate or extent of urea catabolic process. GO:1901715 regulation of gamma-aminobutyric acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901715 regulation of gamma-aminobutyric acid breakdown|regulation of GABA catabolic process|regulation of 4-aminobutyrate catabolic process|regulation of 4-aminobutyrate catabolism|regulation of GABA catabolism|regulation of gamma-aminobutyric acid catabolism|regulation of 4-aminobutanoate catabolic process|regulation of gamma-aminobutyric acid degradation|regulation of 4-aminobutanoate catabolism Any process that modulates the frequency, rate or extent of gamma-aminobutyric acid catabolic process. UBERON:0003859 forelimb mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003859 superior member mesenchyme|mesenchyme of forelimb|mesenchyme of superior member|fore limb mesenchyme|anteriormost limb mesenchyme|upper extremity mesenchyme|mesenchyme of anteriormost limb|mesenchyme of upper extremity|mesenchyme of fore limb|wing mesenchyme Mesenchyme that is part of a developing forelimb [Automatically generated definition]. GO:1901712 positive regulation of homoserine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901712 up regulation of homoserine biosynthesis|up regulation of homoserine biosynthetic process|upregulation of homoserine synthesis|positive regulation of homoserine biosynthesis|activation of homoserine biosynthetic process|upregulation of homoserine formation|up-regulation of homoserine anabolism|activation of homoserine biosynthesis|up-regulation of homoserine synthesis|activation of homoserine anabolism|up-regulation of homoserine formation|up-regulation of homoserine biosynthetic process|up-regulation of homoserine biosynthesis|activation of homoserine synthesis|positive regulation of homoserine anabolism|activation of homoserine formation|up regulation of homoserine anabolism|positive regulation of homoserine synthesis|up regulation of homoserine synthesis|upregulation of homoserine biosynthetic process|upregulation of homoserine biosynthesis|positive regulation of homoserine formation|up regulation of homoserine formation|upregulation of homoserine anabolism Any process that activates or increases the frequency, rate or extent of homoserine biosynthetic process. UBERON:0003856 uncondensed odontogenic mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003856 enamel organ mesenchyme|dental mesenchyme|dental organ mesenchyme|tooth enamel organ mesenchyme|tooth mesenchyme Mesenchyme enclosed by a dental organ that gives rise to an odontogenic papilla. GO:1901713 negative regulation of urea catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901713 inhibition of urea decomposition|inhibition of urea catabolism|downregulation of urea catabolic process|down regulation of urea breakdown|inhibition of urea degradation|down regulation of urea catabolic process|inhibition of urea catabolic process|down regulation of urea catabolism|inhibition of urea breakdown|downregulation of urea catabolism|negative regulation of urea decomposition|down-regulation of urea decomposition|down-regulation of urea degradation|negative regulation of urea degradation|down-regulation of urea breakdown|negative regulation of urea catabolism|negative regulation of urea breakdown|down-regulation of urea catabolism|downregulation of urea decomposition|downregulation of urea degradation|down-regulation of urea catabolic process|down regulation of urea decomposition|down regulation of urea degradation|downregulation of urea breakdown Any process that stops, prevents or reduces the frequency, rate or extent of urea catabolic process. GO:0045226 extracellular polysaccharide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045226 extracellular polysaccharide anabolism|extracellular polysaccharide synthesis|extracellular polysaccharide formation|extracellular polysaccharide biosynthesis The chemical reactions and pathways resulting in the formation of polysaccharides used in extracellular structures. GO:1901710 regulation of homoserine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901710 regulation of homoserine anabolism|regulation of homoserine synthesis|regulation of homoserine biosynthesis|regulation of homoserine formation Any process that modulates the frequency, rate or extent of homoserine biosynthetic process. GO:1901711 negative regulation of homoserine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901711 inhibition of homoserine anabolism|down regulation of homoserine formation|inhibition of homoserine synthesis|negative regulation of homoserine biosynthesis|down-regulation of homoserine biosynthetic process|down-regulation of homoserine biosynthesis|inhibition of homoserine formation|negative regulation of homoserine anabolism|down-regulation of homoserine anabolism|inhibition of homoserine biosynthetic process|down-regulation of homoserine synthesis|negative regulation of homoserine synthesis|inhibition of homoserine biosynthesis|negative regulation of homoserine formation|down-regulation of homoserine formation|downregulation of homoserine anabolism|down regulation of homoserine biosynthesis|downregulation of homoserine synthesis|down regulation of homoserine biosynthetic process|down regulation of homoserine anabolism|downregulation of homoserine formation|downregulation of homoserine biosynthesis|down regulation of homoserine synthesis|downregulation of homoserine biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of homoserine biosynthetic process. GO:0045227 capsule polysaccharide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045227 capsule polysaccharide synthesis|capsule polysaccharide formation|capsule polysaccharide biosynthesis|capsular polysaccharide biosynthesis|capsular polysaccharide biosynthetic process|capsule polysaccharide anabolism The chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi. GO:0045224 positive regulation of CD4 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045224 up regulation of CD4 biosynthetic process|positive regulation of CD4 anabolism|positive regulation of CD4 synthesis|positive regulation of CD4 formation|upregulation of CD4 biosynthetic process|stimulation of CD4 biosynthetic process|up-regulation of CD4 biosynthetic process|activation of CD4 biosynthetic process|positive regulation of CD4 biosynthetic process|positive regulation of CD4 biosynthesis Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4. GO:0045225 negative regulation of CD4 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045225 downregulation of CD4 biosynthetic process|negative regulation of CD4 anabolism|down regulation of CD4 biosynthetic process|inhibition of CD4 biosynthetic process|negative regulation of CD4 synthesis|negative regulation of CD4 formation|down-regulation of CD4 biosynthetic process|negative regulation of CD4 biosynthetic process|negative regulation of CD4 biosynthesis Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4. GO:0045222 CD4 biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045222 CD4 anabolism|CD4 synthesis|CD4 formation|CD4 biosynthesis The chemical reactions and pathways resulting in the formation of CD4, a CD marker that occurs on T-helper cells and is involved in MHC class II restricted interactions. CHEBI:85452 2'-deoxycytidine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85452 GO:0045223 regulation of CD4 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045223 regulation of CD4 formation|regulation of CD4 biosynthetic process|regulation of CD4 biosynthesis|regulation of CD4 anabolism|regulation of CD4 synthesis Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4. GO:0045220 positive regulation of FasL production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045220 upregulation of FasL biosynthetic process|positive regulation of FasL anabolism|positive regulation of FasL synthesis|up regulation of FasL biosynthetic process|positive regulation of FasL formation|positive regulation of FasL biosynthetic process|positive regulation of FasL biosynthesis|activation of FasL biosynthetic process|stimulation of FasL biosynthetic process|up-regulation of FasL biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of FasL. CHEBI:85454 5-methyl dCMP(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85454 GO:0045221 negative regulation of FasL production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045221 negative regulation of FasL anabolism|down regulation of FasL biosynthetic process|negative regulation of FasL synthesis|downregulation of FasL biosynthetic process|negative regulation of FasL formation|negative regulation of FasL biosynthetic process|negative regulation of FasL biosynthesis|down-regulation of FasL biosynthetic process|inhibition of FasL biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of FasL. CHEBI:36413 anabolic agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36413 GO:0060840 artery development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060840 The progression of the artery over time, from its initial formation to the mature structure. An artery is a blood vessel that carries blood away from the heart to a capillary bed. GO:0060841 venous blood vessel development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060841 The progression of the venous blood vessel over time from its initial formation to the mature structure. Venous blood vessels carry blood back to the heart after the capillary bed. CHEBI:36416 mancude organic heterotricyclic parent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36416 GO:0060842 arterial endothelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060842 The process in which a relatively unspecialized endothelial cell acquires specialized features of an arterial endothelial cell, a thin flattened cell that lines the inside surfaces of arteries. GO:0060843 venous endothelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060843 The process in which a relatively unspecialized endothelial cell acquires specialized features of a venous endothelial cell, a thin flattened cell that lines the inside surfaces of veins. GO:0045228 slime layer polysaccharide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045228 slime layer polysaccharide anabolism|slime layer polysaccharide synthesis|slime layer polysaccharide formation|slime layer polysaccharide biosynthesis The chemical reactions and pathways resulting in the formation of polysaccharides in the slime layer, a diffused layer of polysaccharide exterior to the bacterial cell wall. GO:0060844 arterial endothelial cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060844 The commitment of a cell to an arterial endothelial cell fate and its capacity to differentiate into an arterial endothelial cell. GO:0045229 external encapsulating structure organization biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0045229 external encapsulating structure organisation|external encapsulating structure organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of external structures that lie outside the plasma membrane and surround the entire cell. GO:0060845 venous endothelial cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060845 The commitment of a cell to a venous endothelial cell fate and its capacity to differentiate into an venous endothelial cell. UBERON:0003865 distal phalanx of manus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003865 phalanx distalis manus|distal phalanx of finger|hand distal phalanx|distal manual phalanx|terminal phalanx of hand|distal phalanx of manual digit|ungual phalanx of hand|distal phalanx of hand A distal phalanx that is part of a finger [Automatically generated definition]. GO:0060846 blood vessel endothelial cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060846 The commitment of a cell to a blood vessel endothelial cell fate and its capacity to differentiate into a blood vessel endothelial cell. UBERON:0003866 middle phalanx of pes biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003866 phalanx media pedis|middle phalanx of toe|middle pedal phalanx|middle phalanx of foot|foot middle phalanx A middle phalanx that is part of a toe [Automatically generated definition]. GO:0060847 endothelial cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060847 The process involved in the specification of identity of an endothelial cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. GO:0060848 endothelial cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060848 A process involved in cell fate commitment of an endothelial cell. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment. UBERON:0003864 middle phalanx of manus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003864 phalanx media manus|middle phalanx of manual digit|middle manual phalanx|middle phalanx of hand|middle phalanx of finger|hand middle phalanx A middle phalanx that is part of a finger [Automatically generated definition]. GO:0060849 obsolete regulation of transcription involved in lymphatic endothelial cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060849 OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a venous endothelial cell to a lymphatic endothelial cell. UBERON:0003861 neural arch biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003861 vertebra neural arch|dorsal arcocentrum|arcus vertebrae|vertebra dorsal arch|arcus vertebrae|arcus vertebrae (vertebralis)|arcus vertebra posterior part of a vertebra that consists of a pair of pedicles and a pair of laminae, and supports seven processes: four articular processes, two transverse processes one spinous process[WP]. ZFA: A neural arch encloses the neural canal and typically meets its partner to form a neural spine. . UBERON:0003860 hindlimb mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003860 mesenchyme of hind limb|mesenchyme of lower extremity|mesenchyme of hindlimb|lower extremity mesenchyme|hind limb mesenchyme|inferior member mesenchyme|mesenchyme of inferior member Mesenchyme that is part of a developing hindlimb [Automatically generated definition]. CHEBI:131797 S-(2-carboxy-2-methylbut-3-en-2-yl)glutathione(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131797 CHEBI:131798 S-(2-methyl-1-oxobut-3-en-2-yl)glutathione(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131798 GO:0035892 modulation of platelet aggregation in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035892 regulation of platelet aggregation in other organism|modulation by organism of platelet aggregation in other organism Any process in which an organism modulates the frequency, rate or extent of platelet aggregation in another organism. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules. GO:0035893 negative regulation of platelet aggregation in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035893 suppression of platelet aggregation in other organism|downregulation of platelet aggregation in other organism|inhibition of platelet aggregation in other organism|down-regulation of platelet aggregation in other organism Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of platelet aggregation in a second organism. GO:0035894 positive regulation of platelet aggregation in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035894 upregulation of platelet aggregation in other organism|up-regulation of platelet aggregation in other organism Any process in which an organism activates, maintains or increases the frequency, rate or extent of platelet aggregation in another organism. GO:0035895 modulation of mast cell degranulation in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035895 regulation of mast cell degranulation in other organism Any process in which an organism modulates the frequency, rate or extent of blood mast cell degranulation in another organism. Mast cell degranulation is the regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell. GO:0035896 positive regulation of mast cell degranulation in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035896 upregulation of mast cell degranulation in other organism|up-regulation of mast cell degranulation in other organism Any process in which an organism increases the frequency, rate or extent of blood mast cell degranulation in another organism. GO:0035897 proteolysis in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035897 The chemical reactions and pathways performed by an organism resulting in the hydrolysis of proteins in another organism by cleavage of their peptide bonds. GO:0035898 parathyroid hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035898 PTH secretion|parathyrin secretion|parathormone secretion The regulated release of parathyroid hormone into the circulatory system. GO:0035899 negative regulation of blood coagulation in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035899 inhibition of blood coagulation in other organism|negative regulation of blood clotting in other organism|downregulation of blood coagulation in other organism|suppression of blood coagulation in other organism|down-regulation of blood coagulation in other organism Any process in which an organism stops, prevents or reduces the frequency, rate or extent of blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot. GO:0035890 exit from host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035890 ejection from host The directed movement of an organism out of the body, tissues or cells of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0035891 exit from host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035891 host cell exit|ejection from host cell The directed movement of an organism out of a cell of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0035889 otolith tethering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035889 The attachment of a developing otolith to the kinocilia of tether cells in the inner ear. PATO:0001873 cylindrical biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PATO_0001873 tubulate|rod-like|rod-shaped A convex 3-D shape quality inhering in a bearer by virtue of the bearer's exhibiting a consistently-sized round cross section. GO:0035881 amacrine cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035881 amacrine neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of an amacrine cell, an interneuron generated in the inner nuclear layer (INL) of the vertebrate retina. Amacrine cells integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. Amacrine cells lack large axons. GO:0035882 defecation rhythm biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035882 defecation cycle|defecation behavior|defecation motor program|DMP The rhythmic process of defecation that consists of an intestinal oscillator which regulates calcium waves. These waves in turn control a stereotypical, three-part pattern of muscle contractions. In some organisms, defecation can recur with a regularity more frequent than every 24 hours. For example, in a well-fed Caenorhabditis elegans, the defecation motor program occurs approximately every 45 seconds, and is temperature- and touch-compensated. GO:0035883 enteroendocrine cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035883 The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an enteroendocrine cell. Enteroendocrine cells are hormonally active epithelial cells in the gut that constitute the diffuse neuroendocrine system. GO:0035884 arabinan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035884 The chemical reactions and pathways resulting in the formation of arabinan, a polysaccharide composed of arabinose residues. GO:0035885 exochitinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035885 RHEA:50672|MetaCyc:RXN-12309 Catalysis of the hydrolysis of terminal 1,4-beta-linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. Typically, exochitinases progressively cleave off two subunits from the reducing or non-reducing ends of the chitin chain. GO:0035886 vascular associated smooth muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035886 vascular smooth muscle cell differentiation|VSMC differentiation|vascular associated smooth muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a vascular smooth muscle cell. GO:0035887 aortic smooth muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035887 The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell surrounding the aorta. GO:0035888 isoguanine deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035888 2-oxoadenine deaminase activity|2-hydroxyadenine deaminase activity Catalysis of the reaction: isoguanine + H2O = xanthine + NH3. GO:0035880 embryonic nail plate morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035880 The process, occurring in the embryo, by which the anatomical structures of a nail plate are generated and organized. The nail plate is the hard and translucent portion of the nail, composed of keratin, and serves to protect the tips of digits. GO:0035878 nail development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035878 The process whose specific outcome is the progression of a nail over time, from its formation to the mature structure. A nail is a horn-like envelope covering the outer end of a finger or toe, and consists of the nail plate, the nail matrix and the nail bed below it, and the grooves surrounding it. GO:0035879 plasma membrane lactate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035879 lactate plasma membrane transport The directed movement of lactate across a plasma membrane. GO:0035870 dITP diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035870 EC:3.6.1.66|KEGG_REACTION:R03531|RHEA:28342|MetaCyc:RXN0-1602|Reactome:R-HSA-2509838 deoxyinosine triphosphate pyrophosphatase activity|dITP pyrophosphatase activity|2'-Deoxyinosine-5'-triphosphate pyrophosphohydrolase activity Catalysis of the reaction: dITP + H2O = dIMP + diphosphate. CHEBI:131780 2-hydroxyisobutanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131780 GO:0035871 protein K11-linked deubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035871 protein K11-linked deubiquitylation|protein K11-linked deubiquitinylation A protein deubiquitination process in which a K11-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 11 of the ubiquitin monomers, is removed from a protein. GO:0035872 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035872 nucleotide-binding domain leucine-rich repeat containing receptor signaling pathway|NLR signaling pathway|nucleotide-binding domain, leucine rich repeat containing receptor signal transduction pathway|nucleotide-binding domain, leucine rich repeat containing receptor signalling pathway|nucleotide-binding domain, leucine rich repeat containing receptor signal transduction|NOD-like receptor signaling pathway A series of molecular signals generated as a consequence of a nucleotide-binding domain, leucine rich repeat containing receptor (NLR) binding to one of its physiological ligands. NLRs are cytoplasmic receptors defined by their tripartite domain architecture that contains: a variable C-terminus, a middle nucleotide-binding domain, and a LRR domain that is variable in the repeats composition and number. The NLR signaling pathway begins with binding of a ligand to a NLR receptor and ends with regulation of a downstream cellular process. GO:0035873 lactate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035873 lactate membrane transport The process in which lactate is transported across a membrane. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices. CHEBI:131783 indolmycenate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131783 GO:0035874 cellular response to copper ion starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035874 cellular response to copper starvation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of copper ions. GO:0035875 maintenance of meiotic sister chromatid cohesion, centromeric biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035875 maintenance of sister chromatin cohesion at centromere at meiosis I|maintenance of centromeric meiotic sister chromatin cohesion|maintenance of meiotic sister chromatin cohesion at centromere The process in which the association between sister chromatids of a replicated chromosome along the length of the centromeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle. GO:0035876 maintenance of meiotic sister chromatid cohesion, arms biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035876 maintenance of sister chromatin cohesion along arms at meiosis I|maintenance of meiotic sister chromatin cohesion along arms The process in which the association between sister chromatids of a replicated chromosome along the length of the chromosome arms, is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle. GO:0035877 death effector domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035877 DED binding Interacting selectively and non-covalently with a DED domain (death effector domain) of a protein, a homotypic protein interaction module composed of a bundle of six alpha-helices that is related in structure to the death domain (DD). GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035867 A protein complex that consists of an alphav-beta3 integrin complex bound to insulin-like growth factor-1 (IGF-1) and type I insulin-like growth factor receptor (IGF1R). IGF1R is a heterotetramer that consists of two alpha-subunits and two beta-subunits. GO:0035868 alphav-beta3 integrin-HMGB1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035868 alphaV-beta3 integrin-HMGB1 complex|alphav-beta3 integrin-high mobility group box 1 complex A protein complex that consists of an alphav-beta3 integrin complex bound to high mobility group box 1 protein. GO:0035869 ciliary transition zone biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035869 cilial transition zone|connecting cilium|cilium transition zone A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm. CHEBI:131759 CMP-5'-phosphonoformic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131759 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035860 GDNF receptor signaling pathway|glial cell derived neurotrophic factor receptor signaling pathway|glial cell line-derived neurotrophic factor receptor signalling pathway|glial cell-derived neurotrophic factor receptor signalling pathway The series of molecular signals generated as a consequence of a glial cell-derived neurotrophic factor receptor binding to one of its physiological ligands. GO:0035861 site of double-strand break biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035861 DNA damage foci|IRIF|ionizing radiation-induced foci|DNA damage focus|site of DSB A region of a chromosome at which a DNA double-strand break has occurred. DNA damage signaling and repair proteins accumulate at the lesion to respond to the damage and repair the DNA to form a continuous DNA helix. GO:0035862 dITP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035862 2'-Deoxyinosine-5'-triphosphate metabolic process|deoxyinosine triphosphate (2'-deoxyinosine 5'-triphosphate) metabolic process|deoxyinosine 5'-triphosphate metabolic process|dITP metabolism|2'-Deoxyinosine 5'-triphosphate metabolic process The chemical reactions and pathways involving dITP (deoxyinosine triphosphate (2'-deoxyinosine 5'-triphosphate). dITP is a deoxyinosine phosphate compound having a triphosphate group at the 5'-position. GO:0035863 dITP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035863 2'-Deoxyinosine-5'-triphosphate catabolic process|dITP catabolism|deoxyinosine triphosphate (2'-deoxyinosine 5'-triphosphate) catabolic process|dITP degradation|deoxyinosine 5'-triphosphate catabolic process|dITP breakdown|2'-Deoxyinosine 5'-triphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of dITP, a deoxyinosine phosphate compound having a triphosphate group at the 5'-position. GO:0035864 response to potassium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035864 response to potassium|response to K+ ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus. GO:0035865 cellular response to potassium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035865 cellular response to K+ ion|cellular response to potassium Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus. GO:0035866 alphav-beta3 integrin-PKCalpha complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035866 alphav-beta3 integrin-protein kinase C alpha complex|alphav-beta3 integrin-PKCa complex A protein complex that consists of an alphav-beta3 integrin complex bound to protein kinase C alpha. GO:0035856 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035856 CHEBI:131766 (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131766 GO:0035857 eosinophil fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035857 eosinophil cell fate specification The process involved in the specification of identity of an eosinophil cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. CHEBI:131767 D-erythrulose 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131767 GO:0035858 eosinophil fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035858 eosinophil cell fate determination The cell fate determination process in which a cell becomes capable of differentiating autonomously into an eosinophil cell regardless of its environment; upon determination, the cell fate cannot be reversed. GO:0035859 Seh1-associated complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035859 SEA complex|GATOR complex A protein complex that associates dynamically with the vacuolar membrane, and is proposed to have a role in membrane-associated trafficking or regulatory processes. In S. cerevisiae the complex contains Seh1p, Sec13p, Npr2p, Npr3p, Iml1p, Mtc5p, Rtc1p, and Sea4p. CHEBI:61401 L-alanyl-gamma-D-glutamyl-meso-diaminopimelate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61401 CHEBI:61402 ITP(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61402 GO:0035850 epithelial cell differentiation involved in kidney development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035850 The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an epithelial cell that characterize the cells of the kidney as it progresses from its formation to the mature state. GO:0035851 Krueppel-associated box domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035851 Krueppel-associated box binding|KRAB domain binding Interacting selectively and non-covalently with a Krueppel-associated box (KRAB) domain of a protein. The approximately 75 amino acid KRAB domain is enriched in charged amino acids, and is found in the N-terminal regions of many zinc finger-containing transcription factors. GO:0035852 horizontal cell localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035852 horizontal cell positioning|retinal horizontal cell positioning|horizontal cell localisation|laminar positioning of retinal horizontal cell Any process in which a horizontal cell is transported to, and/or maintained in, a specific location within the inner nuclear layer (INL) of the retina. A horizontal cell is a neuron that laterally connects other neurons in the inner nuclear layer (INL) of the retina. Targeting of retinal neurons to the appropriate lamina is vital to establish the architecture of the retina. CHEBI:61405 trans-tetradec-2-enoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61405 CHEBI:61406 trans-dec-2-enoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61406 GO:0035853 chromosome passenger complex localization to spindle midzone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035853 CPC localization to spindle midzone|chromosome passenger complex localization to spindle equator|chromosome passenger complex localization to central spindle|CPC complex localization to spindle midzone|chromosomal passenger complex localization to spindle midzone|chromosome passenger complex localisation to spindle midzone A cellular protein complex localization that acts on a chromosome passenger complex; as a result, the complex is transported to, or maintained in, a specific location at the spindle midzone. A chromosome passenger complex is a protein complex that contains the BIR-domain-containing protein Survivin, Aurora B kinase, INCENP and Borealin, and coordinates various events based on its location to different structures during the course of mitosis. The spindle midzone is the area in the center of the spindle where the spindle microtubules from opposite poles overlap. GO:0035854 eosinophil fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035854 eosinophil cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a eosinophil cell. A eosinophil is any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. CHEBI:61403 psicosyllysine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61403 CHEBI:61404 dATP(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61404 GO:0035855 megakaryocyte development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035855 megakaryocyte cell development The process whose specific outcome is the progression of a megakaryocyte cell over time, from its formation to the mature structure. Megakaryocyte development does not include the steps involved in committing a cell to a megakaryocyte fate. A megakaryocyte is a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow. CHEBI:61409 dihydroxyphenylacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61409 CHEBI:61407 methoxycinnamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61407 GO:0035845 photoreceptor cell outer segment organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035845 photoreceptor outer segment organization|photoreceptor cell outer segment organisation A process that is carried out at the cellular level and results in the assembly, arrangement of constituent parts, or disassembly of the outer segment of a photoreceptor cell, a sensory cell that reacts to the presence of light. The outer segment of the photoreceptor cell contains the light-absorbing materials. GO:0035846 oviduct epithelium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035846 fallopian tube epithelium development The progression of the oviduct epithelium over time from its initial formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. The oviduct epithelium is the specialized epithelium that lines the oviduct. GO:0035847 uterine epithelium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035847 uterus epithelial development The progression of an epithelium of the uterus over time from its initial formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. CHEBI:131735 4-[(2-hydroxyethoxy)carbonyl]benzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131735 GO:0035848 oviduct morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035848 fallopian tube morphogenesis The process in which anatomical structures of the oviduct are generated and organized. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. GO:0035849 nephric duct elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035849 The process in which the nephric duct grows along its axis. A nephric duct is a tube that drains a primitive kidney. CHEBI:131737 androstane ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131737 CHEBI:131739 lysophosphatidylcholine (18:1/0:0) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_131739 CHEBI:36489 17beta-estradiol 3-glucosiduronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36489 CHEBI:61413 oxa fatty acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61413 CHEBI:61410 oxa fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61410 CHEBI:36487 13-(beta-D-glucosyloxy)docosanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36487 CHEBI:36488 dammarane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36488 GO:0035840 old growing cell tip biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035840 old growing cell end A cell tip which has existed for at least one complete cell cycle, and at which polarized growth occurs. For example, in fission yeast the cell end that existed prior to cell division grows immediately after division, and contains a distinctive complement of proteins including actin cytoskeletal structures. CHEBI:61411 divinyl ether fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61411 GO:0035841 new growing cell tip biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035841 new cell tip after activation of bipolar cell growth|post-new end take-off new cell tip|post-NETO new cell tip|post-NETO new cell end A cell tip that was newly formed at the last cell division, and that has started to grow after the cell has activated bipolar cell growth (i.e. in which new end take-off, NETO, has taken place). New end take-off is when monopolar cells initiate bipolar growth. GO:0035842 old cell tip after activation of bipolar cell growth biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035842 post-new end take-off old cell tip|post-NETO old cell end|post-NETO old cell tip A cell tip which has existed for at least one complete cell cycle, and at which polarized growth occurs, which is part of a cell that has activated bipolar cell growth (i.e. in which new end take-off, NETO, has taken place). For example, in fission yeast the cell end that existed prior to cell division grows immediately after division, and contains a distinctive complement of proteins including actin cytoskeletal structures. CHEBI:61417 TDP(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61417 GO:0035843 endonuclear canal biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035843 A membrane-bound structure present in the nucleus of a spermatozoon. There is variation in the number of endonuclear canals between sperm of different organisms, and some species lack these structures altogether. The endonuclear canal may provide a supporting role for the sperm nucleus, and originates during spermiogenesis from an invagination of the nuclear envelope. CHEBI:61414 ferrichromes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61414 GO:0035844 cloaca development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035844 cloacal development The process whose specific outcome is the progression of the cloaca over time, from it's formation to the mature structure. The cloaca is the common chamber into which intestinal, genital and urinary canals open in vertebrates. CHEBI:36481 oleanane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36481 CHEBI:36482 hopane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36482 CHEBI:36480 bisabolane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36480 CHEBI:36485 lupane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36485 CHEBI:36486 13-(beta-D-glucosyloxy)docosanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36486 CHEBI:36483 protostane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36483 CHEBI:36484 hopan-22-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36484 GO:0035834 indole alkaloid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035834 indole alkaloid metabolism The chemical reactions and pathways involving an indole alkaloid, an alkaloid containing an indole skeleton. GO:0035835 indole alkaloid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035835 indole alkaloid synthesis|indole alkaloid formation|indole alkaloid biosynthesis|indole alkaloid anabolism The chemical reactions and pathways resulting in the formation of an indole alkaloid, an alkaloid containing an indole skeleton. CHEBI:131745 lysophosphatidylethanolamine (0:0/18:2) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131745 GO:0035836 ergot alkaloid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035836 ergot alkaloid metabolism The chemical reactions and pathways involving an ergot alkaloid, an indole alkaloid. GO:0035837 ergot alkaloid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035837 ergot alkaloid biosynthesis|ergot alkaloid anabolism|ergot alkaloid synthesis|ergot alkaloid formation The chemical reactions and pathways resulting in the formation of an ergot alkaloid. CHEBI:131747 lanostane ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131747 CHEBI:131748 ergostane ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_131748 GO:0035838 growing cell tip biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035838 growing cell end The region at either end of the longest axis of a cylindrical or elongated cell, where polarized growth occurs. GO:0035839 non-growing cell tip biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035839 new cell end|non-growing cell end A cell tip at which no growth takes place. For example, in fission yeast the cell end newly formed by cell division does not grow immediately upon its formation, and lacks actin cytoskeletal structures. CHEBI:36498 galactosylceramide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36498 GO:0035830 palmatine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035830 palmatine metabolism The chemical reactions and pathways involving palmatine, a berberine alkaloid found in many plants. GO:0035831 palmatine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035831 palmatine anabolism|palmatine biosynthesis|palmatine synthesis|palmatine formation The chemical reactions and pathways resulting in the formation of palmatine, a berberine alkaloid found in many plants. GO:0035832 berbamunine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035832 berbamunine metabolism The chemical reactions and pathways involving berbamunine, an isoquinoline alkaloid. CHEBI:61425 psicosyllysine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61425 GO:0035833 berbamunine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035833 berbamunine biosynthesis|berbamunine anabolism|berbamunine synthesis|berbamunine formation The chemical reactions and pathways resulting in the formation of berbamunine, an isoquinoline alkaloid. CHEBI:36492 (+)-isomenthone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36492 CHEBI:36493 isomenthone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36493 CHEBI:61429 dGTP(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61429 CHEBI:36491 2-methoxy-17beta-estradiol 3-O-(beta-D-glucuronide) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36491 CHEBI:36496 (-)-isomenthone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36496 GO:0045196 establishment or maintenance of neuroblast polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045196 establishment and/or maintenance of neuroblast cell polarity Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system. GO:0070152 mitochondrial isoleucyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070152 The process of coupling isoleucine to isoleucyl-tRNA in a mitochondrion, catalyzed by isoleucyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. GO:0070153 mitochondrial leucyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070153 The process of coupling leucine to leucyl-tRNA in a mitochondrion, catalyzed by leucyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045197 Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of an epithelial cell. GO:0045194 obsolete oxidized low-density lipoprotein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045194 Ox-LDL catabolism|oxidized low-density lipoprotein degradation|Ox-LDL catabolic process|oxidized low-density lipoprotein breakdown|oxidized low-density lipoprotein catabolic process|oxidized low-density lipoprotein catabolism OBSOLETE. The chemical reactions and pathways resulting in the breakdown of oxidized low-density lipoproteins. GO:0070150 mitochondrial glycyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070150 The process of coupling glycine to glycyl-tRNA in a mitochondrion, catalyzed by glycyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. GO:0070151 mitochondrial histidyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070151 The process of coupling histidine to histidyl-tRNA in a mitochondrion, catalyzed by histidyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. GO:0045195 obsolete gallstone formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045195 gallstone formation OBSOLETE. The formation of gallstones, hard, crystal-like accretions of cholesterol and bile pigments which develop when bile contains too much cholesterol and not enough bile. GO:0045192 obsolete low-density lipoprotein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045192 low-density lipoprotein degradation|LDL catabolism|low-density lipoprotein catabolism|low-density lipoprotein breakdown|low-density lipoprotein catabolic process|LDL catabolic process OBSOLETE. The chemical reactions and pathways resulting in the breakdown of low-density lipoproteins, also known as beta lipoproteins, one of the classes of lipoproteins found in the bloodstream of animals, acting as a carrier for cholesterol and fats. GO:0045193 obsolete acetylated low-density lipoprotein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045193 acetylated low-density lipoprotein degradation|acetylated low-density lipoprotein breakdown|acetylated low-density lipoprotein catabolic process|Ac-LDL catabolic process|Ac-LDL catabolism|acetylated low-density lipoprotein catabolism OBSOLETE. The chemical reactions and pathways resulting in the breakdown of acetylated low-density lipoproteins. GO:0045190 isotype switching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045190 Wikipedia:Immunoglobulin_class_switching class switch recombination|isotype switch recombination|class switching The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus. GO:0045191 regulation of isotype switching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045191 regulation of class switching|regulation of class switch recombination|regulation of isotype switch recombination Any process that modulates the frequency, rate or extent of isotype switching. GO:1901688 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1901688 GO:1901689 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1901689 GO:1901686 glutathione derivative catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901686 glutathione derivative breakdown|glutathione derivative catabolism|glutathione derivative degradation The chemical reactions and pathways resulting in the breakdown of glutathione derivative. GO:1901687 glutathione derivative biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901687 glutathione derivative biosynthesis|glutathione derivative anabolism|glutathione derivative synthesis|glutathione derivative formation The chemical reactions and pathways resulting in the formation of glutathione derivative. GO:1901684 arsenate ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901684 The process in which arsenate is transported across a membrane. GO:1901685 glutathione derivative metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901685 glutathione derivative metabolism The chemical reactions and pathways involving glutathione derivative. GO:1901682 sulfur compound transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901682 sulfur molecular entity transmembrane transporter activity Enables the transfer of a sulfur compound from one side of a membrane to the other. GO:0045198 establishment of epithelial cell apical/basal polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045198 The specification and formation of the apicobasal polarity of an epithelial cell. GO:1901683 arsenate ion transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901683 Enables the transfer of an arsenate ion from one side of a membrane to the other. GO:0045199 maintenance of epithelial cell apical/basal polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045199 The maintenance of the apicobasal polarity of an epithelial cell. GO:1901691 proton binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901691 hydrogen ion binding Interacting selectively and non-covalently with proton. GO:1901692 regulation of compound eye retinal cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901692 Any process that modulates the frequency, rate or extent of compound eye retinal cell apoptotic process. GO:1901690 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1901690 GO:0070158 mitochondrial seryl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070158 The process of coupling serine to seryl-tRNA in a mitochondrion, catalyzed by seryl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. GO:0070159 mitochondrial threonyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070159 The process of coupling threonine to threonyl-tRNA in a mitochondrion, catalyzed by threonyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. GO:0070156 mitochondrial phenylalanyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070156 The process of coupling phenylalanine to phenylalanyl-tRNA in a mitochondrion, catalyzed by phenylalanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. GO:0070157 mitochondrial prolyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070157 The process of coupling proline to prolyl-tRNA in a mitochondrion, catalyzed by prolyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. GO:0070154 mitochondrial lysyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070154 The process of coupling lysine to lysyl-tRNA in a mitochondrion, catalyzed by lysyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. GO:0070155 mitochondrial methionyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070155 The process of coupling methionine to methionyl-tRNA in a mitochondrion, catalyzed by methionyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. GO:0070141 response to UV-A biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070141 response to UVA light stimulus|response to UV-A light stimulus|response to UVA radiation stimulus|response to UV-A radiation stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm. GO:0070142 synaptic vesicle budding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070142 Evagination of a membrane to form a synaptic vesicle. GO:0070140 SUMO-specific isopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070140 Catalysis of the hydrolysis of an isopeptide bond between the small conjugating protein SUMO and a protein to which SUMO has been conjugated. GO:1901699 cellular response to nitrogen compound biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901699 cellular response to nitrogen molecular entity Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus. GO:1901697 olivetolic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901697 olivetolic acid anabolism|olivetolic acid synthesis|olivetolic acid biosynthesis|olivetolic acid formation The chemical reactions and pathways resulting in the formation of olivetolic acid. GO:1901698 response to nitrogen compound biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen molecular entity Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus. GO:1901695 tyramine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901695 tyramine biosynthesis|tyramine anabolism|tyramine synthesis|tyramine formation The chemical reactions and pathways resulting in the formation of tyramine. GO:1901696 cannabinoid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901696 cannabinoid biosynthesis|cannabinoid anabolism|cannabinoid synthesis|cannabinoid formation The chemical reactions and pathways resulting in the formation of cannabinoid. GO:1901693 negative regulation of compound eye retinal cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901693 down-regulation of compound eye retinal cell apoptotic process|inhibition of compound eye retinal cell apoptotic process|down regulation of compound eye retinal cell apoptotic process|downregulation of compound eye retinal cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of compound eye retinal cell apoptotic process. GO:1901694 positive regulation of compound eye retinal cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901694 induction of compound eye retinal cell programmed cell death|up-regulation of compound eye retinal cell apoptotic process|upregulation of compound eye retinal cell apoptotic process|up regulation of compound eye retinal cell apoptotic process|activation of compound eye retinal cell apoptotic process Any process that activates or increases the frequency, rate or extent of compound eye retinal cell apoptotic process. GO:0070149 mitochondrial glutamyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070149 The process of coupling glutamate to glutamyl-tRNA in a mitochondrion, catalyzed by glutamyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. GO:0070147 mitochondrial cysteinyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070147 The process of coupling cysteine to cysteinyl-tRNA in a mitochondrion, catalyzed by cysteinyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. GO:0070148 mitochondrial glutaminyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070148 The process of coupling glutamine to glutaminyl-tRNA in a mitochondrion, catalyzed by glutaminyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. GO:0070145 mitochondrial asparaginyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070145 The process of coupling asparagine to asparaginyl-tRNA in a mitochondrion, catalyzed by asparaginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. GO:0070146 mitochondrial aspartyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070146 The process of coupling aspartate to aspartyl-tRNA in a mitochondrion, catalyzed by aspartyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. GO:0070143 mitochondrial alanyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070143 The process of coupling alanine to alanyl-tRNA in a mitochondrion, catalyzed by alanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. GO:0070144 mitochondrial arginyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070144 The process of coupling arginine to arginyl-tRNA in a mitochondrion, catalyzed by arginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. GO:0070174 negative regulation of enamel mineralization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070174 Any process that stops, prevents, or reduces the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel. GO:0070175 positive regulation of enamel mineralization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070175 Any process that activates or increases the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel. GO:0070172 positive regulation of tooth mineralization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070172 Any process that activates or increases the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures. GO:0070173 regulation of enamel mineralization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070173 Any process that modulates the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel. GO:0070170 regulation of tooth mineralization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070170 Any process that modulates the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures. GO:0070171 negative regulation of tooth mineralization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070171 Any process that stops, prevents, or reduces the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures. GO:0070178 D-serine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070178 D-serine metabolism The chemical reactions and pathways involving D-serine, the D-enantiomer of serine, i.e. (2R)-2-amino-3-hydroxypropanoic acid. GO:0070179 D-serine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070179 D-serine biosynthesis|D-serine anabolism|D-serine synthesis|D-serine formation The chemical reactions and pathways resulting in the formation of D-serine, the D-enantiomer of serine, i.e. (2R)-2-amino-3-hydroxypropanoic acid. D-serine is often formed by racemization of L-serine. GO:0070176 DRM complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070176 DP/Rb/MuvB A transcriptional repressor complex that contains the lin-9, lin-35, lin-37, lin-52, lin-53, lin-5is involved in 4-, dpl-1 and efl-1 proteins, and is involved in cell fate specification. GO:0070177 contractile vacuole discharge biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070177 The regulated release of water from a contractile vacuole to the outside of a cell by fusion of the contractile vacuole membrane with the plasma membrane. GO:0070163 regulation of adiponectin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070163 Any process that modulates the frequency, rate or extent of the regulated release of adiponectin from a cell. GO:0070164 negative regulation of adiponectin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070164 down regulation of adiponectin secretion|downregulation of adiponectin secretion|down-regulation of adiponectin secretion|inhibition of adiponectin secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of adiponectin from a cell. GO:0070161 anchoring junction biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070161 anchoring cell junction A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix. GO:0070162 adiponectin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070162 The regulated release of adiponectin, a protein hormone, by adipose tissue. GO:0070160 tight junction biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070160 Wikipedia:Tight_junction occluding cell junction|occluding junction A cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other. GO:0070169 positive regulation of biomineral tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070169 Any process that activates or increases the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds. GO:0070167 regulation of biomineral tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070167 Any process that modulates the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds. GO:0070168 negative regulation of biomineral tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070168 Any process that stops, prevents, or reduces the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds. GO:0070165 positive regulation of adiponectin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070165 upregulation of adiponectin secretion|up regulation of adiponectin secretion|activation of adiponectin secretion|stimulation of adiponectin secretion|up-regulation of adiponectin secretion Any process that activates or increases the frequency, rate or extent of the regulated release of adiponectin from a cell. GO:0070166 enamel mineralization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070166 enamel formation The process in which calcium salts, mainly carbonated hydroxyapatite, are deposited in tooth enamel. GO:0070196 eukaryotic translation initiation factor 3 complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070196 eIF-3 assembly|eIF3 assembly The aggregation, arrangement and bonding together of a set of components to form the eukaryotic translation initiation factor 3 complex. GO:0070197 meiotic attachment of telomere to nuclear envelope biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070197 attachment of telomeric heterochromatin to nuclear envelope|attachment of telomeric chromatin to nuclear envelope|attachment of telomeres to nuclear envelope The meiotic cell cycle process in which physical connections are formed between telomeric heterochromatin and the nuclear envelope, facilitating bouquet formation. GO:0070194 synaptonemal complex disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070194 The controlled breakdown of a synaptonemal complex. GO:0070195 growth hormone receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070195 A receptor complex that consists of two identical subunits and binds growth hormone. GO:0070192 chromosome organization involved in meiotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070192 chromosome organisation involved in meiosis|meiotic chromosome organization A process of chromosome organization that is involved in a meiotic cell cycle. GO:0070193 synaptonemal complex organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070193 synaptonemal complex organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synaptonemal complex. A synaptonemal complex is a proteinaceous scaffold formed between homologous chromosomes during meiosis. GO:0070190 obsolete inositol hexakisphosphate 1-kinase or 3-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070190 inositol hexakisphosphate 1-kinase or 3-kinase activity OBSOLETE. Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 1-diphospho-1D-myo-inositol (2,3,4,5,6)pentakisphosphate, and ATP + 1D-myo-inositol hexakisphosphate = ADP + 3-diphospho-1D-myo-inositol (1,2,4,5,6)pentakisphosphate. GO:0070191 methionine-R-sulfoxide reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070191 Catalysis of the reaction: L-methionine R-oxide + thioredoxin = L-methionine + thioredoxin disulfide; can act on free oxidized methionine with specificity for the R enantiomer; does not act on oxidized methionine in peptide linkage. Thioredoxin disulfide is the oxidized form of thioredoxin. NCBITaxon:33213 Bilateria organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_33213 GO:0070198 protein localization to chromosome, telomeric region biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070198 protein localisation to chromosome, telomeric region|protein localization to telomere Any process in which a protein is transported to, or maintained at, the telomeric region of a chromosome. GO:0070199 establishment of protein localization to chromosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070199 establishment of protein localisation to chromosome The directed movement of a protein to a specific location on a chromosome. GO:0070185 mitochondrial valyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070185 The process of coupling valine to valyl-tRNA in a mitochondrion, catalyzed by valyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. GO:0070186 growth hormone activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070186 pituitary growth hormone activity|GH activity|placental growth hormone activity The action characteristic of growth hormone, a peptide hormone that is secreted by the anterior pituitary or the placenta into the circulation, and binds to membrane receptors in target tissues to stimulate body growth. GO:0070183 mitochondrial tryptophanyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070183 The process of coupling tryptophan to tryptophanyl-tRNA in a mitochondrion, catalyzed by tryptophanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. GO:0070184 mitochondrial tyrosyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070184 The process of coupling tyrosine to tyrosyl-tRNA in a mitochondrion, catalyzed by tyrosyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. GO:0070181 small ribosomal subunit rRNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070181 SSU rRNA binding|18S rRNA binding Interacting selectively and non-covalently with the small ribosomal subunit RNA (SSU rRNA), a constituent of the small ribosomal subunit. In S. cerevisiae, this is the 18S rRNA. GO:0070182 DNA polymerase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070182 Interacting selectively and non-covalently with a DNA polymerase. GO:0070180 large ribosomal subunit rRNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070180 LSU rRNA binding|25S rRNA binding Interacting selectively and non-covalently with the large ribosomal subunit RNA (LSU rRNA), a constituent of the large ribosomal subunit. In S. cerevisiae, this is the 25S rRNA. OBO:GOCHE_76668 substance with EC 2.7.* (P-containing group transferase) inhibitor role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_76668 NCBITaxon:33208 Metazoa organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_33208 multicellular animals|animals|Animalia|metazoans GO:0070189 kynurenine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070189 kynurenine metabolism The chemical reactions and pathways involving kynurenine, the amino acid 3-(2-aminobenzoyl)-alanine. GO:0070187 shelterin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070187 Pot1-Tpz1 complex|Pot1 complex|telosome A nuclear telomere cap complex that is formed by the association of telomeric ssDNA- and dsDNA-binding proteins with telomeric DNA, and is involved in telomere protection and recruitment of telomerase. The complex is known to contain TERF1, TERF2, POT1, RAP1, TINF2 and ACD in mammalian cells, and Pot1, Tpz1, Rap1, Rif1, Rif2 and Taz1 in Saccharomyces. Taz1 and Rap1 (or their mammalian equivalents) form a dsDNA-binding subcomplex, Pot1 and Tpz1 form an ssDNA-binding subcomplex, and the two subcomplexes are bridged by Poz1, which acts as an effector molecule along with Ccq1. GO:0070188 obsolete Stn1-Ten1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070188 OBSOLETE. A nuclear telomere cap complex that is formed by the association of the Stn1 and Ten1 proteins with telomeric DNA; in some species a third protein is present. CHEBI:141140 medium-chain fatty acyl-AMP(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_141140 OBA:VT2000000 arterial blood pressure trait biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_VT2000000 pressure of arterial blood The pressure of a arterial blood. CHEBI:141131 acyl-AMP(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_141131 GO:0035793 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035793 positive regulation of metanephric mesenchymal cell migration by PDGF receptor-beta signaling pathway|positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signalling pathway|positive regulation of metanephric mesenchymal cell migration by PDGFR-beta signaling pathway|positive regulation of metanephric mesenchymal cell migration by betaPDGF receptor signaling pathway Any process that increases the frequency, rate or extent of metanephric mesenchymal cell migration as a result of the series of molecular signals generated as a consequence of a platelet-derived growth factor receptor-beta binding to one of its physiological ligands. GO:0035794 positive regulation of mitochondrial membrane permeability biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035794 mitochondrial membrane permeability transition|mitochondrial membrane permeabilization|MPT|positive regulation of transport across mitochondrial membrane|mitochondrial permeability transition Any process that increases the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane. GO:0035795 negative regulation of mitochondrial membrane permeability biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035795 mitochondrial membrane impermeabilization|negative regulation of transport across mitochondrial membrane|mitochondrial membrane impermeability Any process that decreases the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane. GO:0035796 ATP-binding cassette (ABC) transporter complex, transmembrane substrate-binding subunit-containing biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035796 energy coupling factor (ECF)-type ABC transporter|energy-coupling factor transporter|ATP-binding cassette (ABC) transporter complex, ECF-type A complex for the transport of metabolites into the cell, consisting of 4 subunits: a transmembrane substrate-binding protein (known as the S component), and an energy-coupling module that comprises two ATP-binding proteins (known as the A and A' components) and a transmembrane protein (known as the T component). Transport of the substrate across the membrane is driven by the hydrolysis of ATP. GO:0035797 tellurite methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035797 SAM-dependent tellurite methyltransferase activity|tellurite methylase activity|S-adenosyl-L-methionine-dependent tellurite methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to tellurite [TeO3(2-)]. Methylated derivatives of tellurite include Te(CH3)2 (dimethyltelluride) and Te2(CH3)2 (dimethylditelluride). GO:0035798 2-alkenal reductase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035798 NADPH:2-alkenal alpha,beta-hydrogenase activity Catalysis of the reaction: n-alkanal + NADP+ = alk-2-enal + NADPH + H+. GO:0035799 ureter maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035799 A developmental process, independent of morphogenetic (shape) change, that is required for the ureter to attain its fully functional state. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut. GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035790 platelet-derived growth factor receptor-alpha signalling pathway|PDGF receptor-alpha signaling pathway|PDGFR-alpha signaling pathway|alphaPDGF receptor signaling pathway A series of molecular signals initiated by the binding of a ligand to an alpha-type platelet-derived growth factor receptor (PDGFalpha) on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0035791 platelet-derived growth factor receptor-beta signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035791 PDGFR-beta signaling pathway|betaPDGF receptor signaling pathway|PDGF receptor-beta signaling pathway|platelet-derived growth factor receptor-beta signalling pathway A series of molecular signals initiated by the binding of a ligand to a beta-type platelet-derived growth factor receptor (PDGFbeta) on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0035792 host cell postsynaptic membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035792 other organism postsynaptic membrane|other organism post-synaptic membrane A postsynaptic membrane that is part of a host cell. A postsynaptic membrane is a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters transmit the signal across the synaptic cleft to the postsynaptic membrane. GO:1901608 regulation of vesicle transport along microtubule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901608 regulation of microtubule-based vesicle localization Any process that modulates the frequency, rate or extent of vesicle transport along microtubule. GO:1901609 negative regulation of vesicle transport along microtubule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901609 inhibition of vesicle transport along microtubule|down-regulation of microtubule-based vesicle localization|negative regulation of microtubule-based vesicle localization|downregulation of microtubule-based vesicle localization|down regulation of vesicle transport along microtubule|down regulation of microtubule-based vesicle localization|downregulation of vesicle transport along microtubule|inhibition of microtubule-based vesicle localization|down-regulation of vesicle transport along microtubule Any process that stops, prevents or reduces the frequency, rate or extent of vesicle transport along microtubule. GO:1901606 alpha-amino acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901606 alpha-amino acid catabolism|alpha-amino acid degradation|alpha-amino acid breakdown The chemical reactions and pathways resulting in the breakdown of an alpha-amino acid. GO:1901607 alpha-amino acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901607 alpha-amino acid anabolism|alpha-amino acid synthesis|alpha-amino acid formation|alpha-amino acid biosynthesis The chemical reactions and pathways resulting in the formation of an alpha-amino acid. GO:1901604 dethiobiotin transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901604 Enables the transfer of dethiobiotin from one side of a membrane to the other. GO:1901605 alpha-amino acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901605 alpha-amino acid metabolism The chemical reactions and pathways involving an alpha-amino acid. GO:1901602 dethiobiotin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901602 Interacting selectively and non-covalently with dethiobiotin. GO:1901603 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1901603 GO:0045116 protein neddylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045116 RUB1-protein conjugation Covalent attachment of the ubiquitin-like protein NEDD8 (RUB1) to another protein. GO:1901600 strigolactone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901600 strigolactone metabolism The chemical reactions and pathways involving strigolactone. CHEBI:85360 L-dihydroanticapsin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85360 CHEBI:61393 fructosyllysine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61393 GO:0045117 azole transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045117 azole transport The directed movement of azoles, heterocyclic compounds found in many biologically important substances, across a lipid bilayer, across a membrane. GO:1901601 strigolactone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901601 strigolactone anabolism|strigolactone synthesis|strigolactone formation|strigolactone biosynthesis The chemical reactions and pathways resulting in the formation of strigolactone. GO:0045114 beta 2 integrin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045114 beta 2 integrin biosynthesis|beta 2 integrin anabolism|beta 2 integrin synthesis|beta 2 integrin formation The chemical reactions and pathways resulting in the formation of beta 2 integrins, a subfamily of integrins which contain the beta 2 subunit. GO:0045115 regulation of beta 2 integrin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045115 regulation of beta 2 integrin anabolism|regulation of beta 2 integrin synthesis|regulation of beta 2 integrin formation|regulation of beta 2 integrin biosynthesis Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta 2 integrins. CHEBI:61392 fructoselysine 6-phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61392 GO:0045112 integrin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045112 integrin biosynthesis|integrin anabolism|integrin synthesis|integrin formation The chemical reactions and pathways resulting in the formation of integrins, a large family of transmembrane proteins that act as receptors for cell-adhesion molecules. GO:0045113 regulation of integrin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045113 regulation of integrin synthesis|regulation of integrin formation|regulation of integrin biosynthesis|regulation of integrin anabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins. GO:0045110 intermediate filament bundle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045110 tonofilament assembly The formation of the bundles of intermediate filaments. Intermediate filament-associated proteins (IFAPs) cross-link intermediate filaments with one another, forming a bundle or a network, and with other cell structures, including the plasma membrane. The organization of intermediate filaments and their supportive function in various cells types depends in large part on their linkage to other cell structures via IFAPs. CHEBI:61395 L-alanyl-D-glutamate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61395 CHEBI:85366 3-hydroxy-2,4-dioxopentyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85366 CHEBI:85367 2-epi-5-epi-valiolone 7-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85367 CHEBI:61396 L-alanyl-L-glutamate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61396 GO:0045111 intermediate filament cytoskeleton biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045111 Cytoskeletal structure made from intermediate filaments, typically organized in the cytosol as an extended system that stretches from the nuclear envelope to the plasma membrane. Some intermediate filaments run parallel to the cell surface, while others traverse the cytosol; together they form an internal framework that helps support the shape and resilience of the cell. CHEBI:85368 dTDP-4-dehydro-2,6-dideoxy-alpha-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85368 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060750 The multiplication or reproduction of mammary gland branch epithelial cells, resulting in the elongation of the branch. The mammary gland branch differs from the bud in that it is not the initial curved portion of the outgrowth. CHEBI:85369 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85369 GO:0060751 branch elongation involved in mammary gland duct branching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060751 mammary gland duct branch elongation The developmental growth process in which a branch of a mammary gland duct elongates. GO:0060752 intestinal phytosterol absorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060752 Any process in which phytosterols are taken up from the contents of the intestine. GO:0060753 regulation of mast cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060753 Any process that modulates the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus. GO:0060754 positive regulation of mast cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060754 Any process that increases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus. GO:0060755 negative regulation of mast cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060755 Any process that decreases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus. GO:0045118 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045118 GO:0045119 azole:proton antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045119 azole:hydrogen antiporter activity|bicyclomycin/sulfathiazole:hydrogen antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + azole(in) = H+(in) + azole(out). Azoles are heterocyclic compounds found in many biologically important substances. GO:0060756 foraging behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060756 Behavior by which an organism locates food. GO:0060757 adult foraging behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060757 Behavior by which an adult locates food. GO:0060758 foraging behavior by probing substrate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060758 Foraging behavior in which an anatomical part of the organism is inserted into the substrate to locate food. GO:0060759 regulation of response to cytokine stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060759 Any process that modulates the rate, frequency, or extent of a response to cytokine stimulus. GO:1901619 obsolete tRNA methylation in response to nitrogen starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901619 OBSOLETE. The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule as a result of deprivation of nitrogen. GO:0045120 pronucleus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045120 Wikipedia:Pronucleus The nucleus of either the ovum or the spermatozoon following fertilization. Thus, in the fertilized ovum, there are two pronuclei, one originating from the ovum, the other from the spermatozoon that brought about fertilization; they approach each other, but do not fuse until just before the first cleavage, when each pronucleus loses its membrane to release its contents. UBERON:0013240 future glans clitoris biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013240 glans of female genital tubercle A future glans that is part of a female genital tubercle. GO:1901617 organic hydroxy compound biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901617 organic hydroxy compound anabolism|organic hydroxy compound synthesis|organic hydroxy compound formation|organic hydroxy compound biosynthesis The chemical reactions and pathways resulting in the formation of organic hydroxy compound. GO:1901618 organic hydroxy compound transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901618 Enables the transfer of organic hydroxy compound from one side of a membrane to the other. UBERON:0013241 embryonic urethral groove biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013241 sulcus urethralis primarius|urethral groove|urethral sulcus The precursor of the urethra GO:1901615 organic hydroxy compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901615 organic hydroxy compound metabolism The chemical reactions and pathways involving organic hydroxy compound. GO:1901616 organic hydroxy compound catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901616 organic hydroxy compound degradation|organic hydroxy compound breakdown|organic hydroxy compound catabolism The chemical reactions and pathways resulting in the breakdown of organic hydroxy compound. GO:1901613 negative regulation of terminal button organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901613 downregulation of terminal bouton organization|downregulation of terminal button organisation|down regulation of bouton organization|down regulation of terminal bouton organization|down regulation of terminal button organisation|downregulation of synaptic bouton organization|inhibition of terminal button organisation|downregulation of bouton organization|inhibition of terminal bouton organization|downregulation of terminal button organization|down regulation of presynaptic bouton organization|down regulation of synaptic bouton organization|down regulation of terminal button organization|inhibition of synaptic bouton organization|downregulation of presynaptic bouton organization|inhibition of terminal button organization|negative regulation of bouton organization|down-regulation of bouton organization|negative regulation of presynaptic bouton organization|down-regulation of presynaptic bouton organization|inhibition of bouton organization|down-regulation of terminal bouton organization|down-regulation of terminal button organisation|negative regulation of terminal bouton organization|negative regulation of terminal button organisation|negative regulation of synaptic bouton organization|inhibition of presynaptic bouton organization|down-regulation of synaptic bouton organization|down-regulation of terminal button organization Any process that stops, prevents or reduces the frequency, rate or extent of terminal button organization. GO:1901614 positive regulation of terminal button organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901614 positive regulation of synaptic bouton organization|up regulation of synaptic bouton organization|up regulation of terminal button organization|upregulation of presynaptic bouton organization|upregulation of terminal bouton organization|upregulation of terminal button organisation|up regulation of bouton organization|positive regulation of bouton organization|activation of bouton organization|upregulation of synaptic bouton organization|upregulation of terminal button organization|up regulation of presynaptic bouton organization|up-regulation of terminal button organisation|up-regulation of terminal bouton organization|activation of presynaptic bouton organization|positive regulation of presynaptic bouton organization|activation of terminal button organisation|activation of terminal bouton organization|up-regulation of synaptic bouton organization|activation of synaptic bouton organization|up-regulation of bouton organization|up-regulation of terminal button organization|activation of terminal button organization|positive regulation of terminal button organisation|positive regulation of terminal bouton organization|up-regulation of presynaptic bouton organization|up regulation of terminal bouton organization|up regulation of terminal button organisation|upregulation of bouton organization Any process that activates or increases the frequency, rate or extent of terminal button organization. GO:1901611 phosphatidylglycerol binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901611 Interacting selectively and non-covalently with phosphatidylglycerol. GO:0045127 N-acetylglucosamine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045127 Reactome:R-HSA-6803771|EC:2.7.1.59|KEGG_REACTION:R01201|RHEA:17417|MetaCyc:N-ACETYLGLUCOSAMINE-KINASE-RXN GlcNAc kinase activity|acetylglucosamine kinase (phosphorylating)|ATP:N-acetyl-D-glucosamine 6-phosphotransferase activity|ATP:2-acetylamino-2-deoxy-D-glucose 6-phosphotransferase activity|2-acetylamino-2-deoxy-D-glucose kinase activity|acetylaminodeoxyglucokinase activity Catalysis of the reaction: N-acetyl-D-glucosamine + ATP = N-acetyl-D-glucosamine 6-phosphate + ADP + 2 H(+). UBERON:0013247 male paramesonephric duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013247 degenerating mesonephric portion of male paramesonephric duct A epithelial tube that develops from a Mullerian duct in a male. Later degenerates. GO:0045128 negative regulation of reciprocal meiotic recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045128 down regulation of meiotic recombination|downregulation of meiotic recombination|suppression of meiotic recombination|down-regulation of meiotic recombination|inhibition of meiotic recombination Any process that decreases the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate. GO:1901612 cardiolipin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901612 Interacting selectively and non-covalently with cardiolipin. CHEBI:85350 CDP-1-palmitoyl-2-arachidonoyl-sn-glycerol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85350 GO:0045125 bioactive lipid receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045125 Combining with a bioactive lipid and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. A bioactive lipid is a lipid for which changes in lipid levels result in functional consequences in a variety of cellular processes. CHEBI:85351 CDP-1,2-diarachidonoyl-sn-glycerol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85351 GO:1901610 positive regulation of vesicle transport along microtubule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901610 up regulation of vesicle transport along microtubule|activation of vesicle transport along microtubule|up-regulation of microtubule-based vesicle localization|activation of microtubule-based vesicle localization|up-regulation of vesicle transport along microtubule|positive regulation of microtubule-based vesicle localization|up regulation of microtubule-based vesicle localization|upregulation of vesicle transport along microtubule|upregulation of microtubule-based vesicle localization Any process that activates or increases the frequency, rate or extent of vesicle transport along microtubule. GO:0045126 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045126 CHEBI:85352 CDP-1-stearoyl-2-linoleoyl-sn-glycerol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85352 GO:0045123 cellular extravasation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045123 Wikipedia:Leukocyte_extravasation leucocyte cellular extravasation|transendothelial leukocyte migration|immune cell cellular extravasation|leukocyte cellular extravasation The migration of a leukocyte from the blood vessels into the surrounding tissue. CHEBI:85353 CDP-1-stearoyl-2-oleoyl-sn-glycerol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85353 GO:0045124 regulation of bone resorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045124 Any process that modulates the frequency, rate or extent of bone tissue loss (resorption). CHEBI:85354 CDP-1-stearoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycerol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85354 GO:0045121 membrane raft biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045121 Wikipedia:Lipid_raft GEM domain|glycolipid-enriched membrane domain|lipid raft Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions. CHEBI:85355 CDP-1,2-dilinoleoyl-sn-glycerol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85355 GO:0045122 aflatoxin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045122 aflatoxin synthesis|aflatoxin formation|aflatoxin biosynthesis|aflatoxin anabolism The chemical reactions and pathways resulting in the formation of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450. CHEBI:85356 CDP-1,2-dioleoyl-sn-glycerol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85356 CHEBI:85357 3-[(1E,4R)-4-hydroxycyclohex-2-en-1-ylidene]pyruvic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85357 GO:0060740 prostate gland epithelium morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060740 The process in which the anatomical structures of epithelia of the prostate gland are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube. GO:0060741 prostate gland stromal morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060741 The process in which the prostate gland stroma is generated and organized. The prostate gland stroma is made up of the mesenchymal or fibroblast cells of the prostate gland. UBERON:0013239 future glans penis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013239 glans of male genital tubercle A future glans that is part of a male genital tubercle. GO:0060742 epithelial cell differentiation involved in prostate gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060742 The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell of the prostate gland. GO:0060743 epithelial cell maturation involved in prostate gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060743 prostate gland epithelial cell development The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the prostate gland to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface. GO:0045129 NAD-independent histone deacetylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045129 AcuC Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction does not require the presence of NAD, and represents the removal of an acetyl group from a histone. GO:0060744 mammary gland branching involved in thelarche biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060744 mammary gland branching involved in puberty The process in which the branching structure of the mammary gland duct is generated and organized during the period of sexual maturity in mammals. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. GO:0060745 mammary gland branching involved in pregnancy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060745 The process in which the branching structure of the mammary gland duct is generated and organized as a part of pregnancy. GO:0060746 parental behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060746 A reproductive behavior in which a parent cares for and rears offspring. GO:0060747 oral incubation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060747 A parental behavior in which fertilized eggs are taken into the mouth and held until hatching. GO:0060748 tertiary branching involved in mammary gland duct morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060748 The branching process in which the mammary gland ducts form tertiary branches off of the secondary branches as part of diestrus and pregnancy. GO:0060749 mammary gland alveolus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060749 The progression of the mammary gland alveolus over time, from its formation to its mature state. The mammary gland alveolus is a sac-like structure that is found in the mature gland. GO:0045130 keratan sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045130 Reactome:R-HSA-2046175|MetaCyc:KERATAN-SULFOTRANSFERASE-RXN|EC:2.8.2.21 3'-phosphoadenylyl-sulfate:keratan 6'-sulfotransferase activity|3'-phosphoadenylylsulfate:keratan sulfotransferase activity|keratan sulphotransferase activity|keratan sulfate Gal-6-sulfotransferase activity|keratan sulfate sulfotransferase activity|3'-phosphoadenylyl keratan sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + keratan = adenosine 3',5'-bisphosphate + keratan 6'-sulfate. GO:0045131 pre-mRNA branch point binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045131 Interacting selectively and non-covalently with a pre-mRNA branch point sequence, located upstream of the 3' splice site. GO:1901628 positive regulation of postsynaptic membrane organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901628 upregulation of postsynaptic membrane organization|up-regulation of postsynaptic membrane organisation|activation of postsynaptic membrane organisation|up-regulation of postsynaptic membrane organization|activation of postsynaptic membrane organization|positive regulation of post-synaptic membrane organization|positive regulation of postsynaptic membrane organisation|up regulation of postsynaptic membrane organisation|up regulation of postsynaptic membrane organization|upregulation of postsynaptic membrane organisation Any process that activates or increases the frequency, rate or extent of postsynaptic membrane organization. UBERON:0013230 nictitans gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013230 superficial gland of the third eyelid|glandula palpebra tertia superficialis|superficial gland of the nictitating membrane|gland of the third eyelid|gland of nictitating membrane A gland producing tears in a third eyelid in the corner of each eye. GO:1901629 regulation of presynaptic membrane organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901629 regulation of pre-synaptic membrane organization|regulation of presynaptic membrane organisation Any process that modulates the frequency, rate or extent of presynaptic membrane organization. GO:1901626 regulation of postsynaptic membrane organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901626 regulation of post-synaptic membrane organization|regulation of postsynaptic membrane organisation Any process that modulates the frequency, rate or extent of postsynaptic membrane organization. GO:1901627 negative regulation of postsynaptic membrane organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901627 down regulation of postsynaptic membrane organization|inhibition of postsynaptic membrane organization|down-regulation of postsynaptic membrane organisation|negative regulation of postsynaptic membrane organisation|down-regulation of postsynaptic membrane organization|negative regulation of post-synaptic membrane organization|downregulation of postsynaptic membrane organisation|down regulation of postsynaptic membrane organisation|inhibition of postsynaptic membrane organisation|downregulation of postsynaptic membrane organization Any process that stops, prevents or reduces the frequency, rate or extent of postsynaptic membrane organization. GO:1901624 negative regulation of lymphocyte chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901624 down regulation of lymphocyte chemotaxis|downregulation of lymphocyte chemotaxis|down-regulation of lymphocyte chemotaxis|inhibition of lymphocyte chemotaxis Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte chemotaxis. GO:1901625 cellular response to ergosterol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901625 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ergosterol stimulus. UBERON:0013235 ventrum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013235 ventral region of organism|ventral part of organism|ventral region|front|front of body proper A major organism subdivisionthat is the entire part of an anatomical structure ventral to a horizontal plane and bounded on one side by the same horizontal plane. GO:1901622 positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901622 up-regulation of hh signaling pathway involved in dorsal/ventral neural tube patterning|activation of hh signaling pathway involved in dorsal/ventral neural tube patterning|upregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning|upregulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|up-regulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|activation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|up-regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning|activation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning|positive regulation of hh signaling pathway involved in dorsal/ventral neural tube patterning|up regulation of hh signaling pathway involved in dorsal/ventral neural tube patterning|up regulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|positive regulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|activation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|positive regulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|up regulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|upregulation of hh signaling pathway involved in dorsal/ventral neural tube patterning|up regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning|up-regulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|upregulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning Any process that activates or increases the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning. GO:0045138 nematode male tail tip morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045138 tail tip morphogenesis|male tail morphogenesis|male tail tip morphogenesis The process in which the anatomical structure of the adult male tail tip is generated and organized. In some species of rhabitid nematodes, the male tail tip undergoes a morphological change such that the most posterior hypodermal cells in the tail (hyp8-11 in C. elegans) fuse and retract anteriorly, changing the shape of the tail from a pointed, tapered cone, or spike, to a rounded, blunt dome. CHEBI:85382 1-heptadecanoyl-2-lauroyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85382 GO:0045139 obsolete copper sensitivity/resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045139 copper sensitivity/resistance OBSOLETE. (Was not defined before being made obsolete). GO:1901623 regulation of lymphocyte chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901623 Any process that modulates the frequency, rate or extent of lymphocyte chemotaxis. CHEBI:85383 1-heptadecanoyl-2-myristoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85383 GO:0045136 development of secondary sexual characteristics biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045136 The process whose specific outcome is the progression of the secondary sexual characteristics over time, from their formation to the mature structures. In humans, these include growth of axillary, chest, and pubic hair, voice changes, testicular/penile enlargement, breast development and menstrual periods. Development occurs in response to sex hormone secretion. GO:1901620 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901620 regulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|regulation of hh signaling pathway involved in dorsal/ventral neural tube patterning|regulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning Any process that modulates the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning. GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901621 down regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning|inhibition of smoothened signaling pathway involved in dorsal/ventral neural tube patterning|negative regulation of hh signaling pathway involved in dorsal/ventral neural tube patterning|down-regulation of hh signaling pathway involved in dorsal/ventral neural tube patterning|down regulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|downregulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|down-regulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|negative regulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|downregulation of hh signaling pathway involved in dorsal/ventral neural tube patterning|down-regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning|down regulation of hh signaling pathway involved in dorsal/ventral neural tube patterning|negative regulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|down-regulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|downregulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|inhibition of hh signaling pathway involved in dorsal/ventral neural tube patterning|down regulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|downregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning|inhibition of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|inhibition of smoothened signalling pathway involved in dorsal/ventral neural tube patterning Any process that stops, prevents or reduces the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning. UBERON:0013238 future glans biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013238 GO:0045137 development of primary sexual characteristics biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045137 The process whose specific outcome is the progression of the primary sexual characteristics over time, from their formation to the mature structures. The primary sexual characteristics are the testes in males and the ovaries in females and they develop in response to sex hormone secretion. CHEBI:85385 1-heptadecanoyl-2-stearoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85385 GO:0045134 uridine-diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045134 MetaCyc:RXN-12197|KEGG_REACTION:R00155|EC:3.6.1.6 uridine diphosphatase activity|UDPase activity|UDP phosphohydrolase activity|uridine 5'-diphosphatase activity Catalysis of the reaction: UDP + H2O = UMP + phosphate. CHEBI:85386 1-heptadecanoyl-2-palmitoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85386 UBERON:0013231 sebaceous gland of eyelid biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013231 Any of the sebaceous glands that are in the eyelid. Examples: gland of Zeis (services eyelashes), gland of Meibom (tarsal gland - unconnected to eyelids). GO:0045135 poly(beta-D-mannuronate) lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045135 MetaCyc:4.2.2.3-RXN|EC:4.2.2.3 alginase activity|poly(beta-D-1,4-mannuronide) lyase activity|alginase I|alginate lyase I activity|alginate lyase activity|poly(mana) alginate lyase activity Catalysis of the reaction: polysaccharides containing beta-D-mannuronate residues = oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl end. This reaction is the eliminative cleavage of polysaccharides containing beta-D-mannuronate residues to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends. UBERON:0013232 serous acinus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013232 acinus of serous gland The secretory unit of a serous gland. The acinar portion is composed of serous secreting cells. GO:0045132 meiotic chromosome segregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045132 The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle. GO:0045133 2,3-dihydroxybenzoate 3,4-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045133 RHEA:18477|EC:1.13.11.14|KEGG_REACTION:R01507|MetaCyc:1.13.11.14-RXN 2,3-dihydroxybenzoic oxygenase activity|2,3-dihydroxybenzoate:oxygen 3,4-oxidoreductase (decyclizing)|2,3-dihydroxybenzoate oxygenase activity|2,3-dihydroxybenzoate 1,2-dioxygenase activity|o-pyrocatechuate oxygenase activity Catalysis of the reaction: 2,3-dihydroxybenzoate + O(2) = 2-hydroxy-3-(3-oxoprop-1-enyl)but-2-enedioate + H(+). GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060770 Any process that decreases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time. GO:0060771 phyllotactic patterning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060771 The radial pattern formation process that results in the formation of plant organs (leaves or leaf-like structures) or flower primordia around a central axis. GO:0060772 leaf phyllotactic patterning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060772 The radial pattern formation process that results in the formation of leaf primordia around the center of a shoot apical meristem. GO:0060773 flower phyllotactic patterning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060773 The radial pattern formation process that results in the formation of floral organ primordia around a central axis in a flower primordium. GO:0060774 auxin mediated signaling pathway involved in phyllotactic patterning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060774 auxin mediated signalling pathway involved in phyllotactic patterning The series of molecular signals generated in response to detection of auxin that contributes to the radial pattern formation process resulting in the formation of leaf or flower primordia around the center of a shoot apical meristem. GO:0060775 planar cell polarity pathway involved in gastrula mediolateral intercalation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060775 The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) contributing to the interdigitation of cells along the mediolateral axis during gastrulation. UBERON:0013228 sweat gland of eyelid biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013228 ciliary gland|ciliary sweat gland of eyelid|ciliary gland of moll|Moll's gland|gland of Moll Glands of Moll, also known as ciliary glands, are modified apocrine sweat glands that are found on the margin of the eyelid. They are next to the base of the eyelashes, and anterior to the Meibomian glands within the distal eyelid margin. These glands are relatively large and tubular-shaped. The glands of Moll are named after Dutch oculist Jacob Anton Moll (1832-1914). Glands of Moll empty into the adjacent lashes. Glands of Moll and Zeis secrete lipid that adds to the superficial layer of the tear film, retarding evaporation. The glands of Moll are prone to infection and blockage of its duct with sebum and cell debris. Blockage of the gland's duct causes swelling which can manifest itself as a stye. GO:0060776 simple leaf morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060776 The leaf morphogenesis process which results in the shaping of a simple leaf. A simple leaf is a leaf in which the lamina is undivided. UBERON:0013229 eyelid gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013229 gland of eyelid Any gland that is part of an eyelid. This includes sebaceous glands (Zeis gland, tarsal gland) and sweat glands (Moll's gland). GO:0060777 compound leaf morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060777 The leaf morphogenesis process that results in the shaping of a compound leaf. A compound leaf is a leaf having two or more distinct leaflets that are evident as such from early in development. GO:0060778 primary leaflet morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060778 The process in which the primary leaflet attains its shape. A primary leaflet is a leaflet that develops directly from the rachis. GO:0060779 secondary leaflet morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060779 The process in which the secondary leaflet attains its shape. A secondary leaflet develops by branching or division of a primary leaflet. GO:0045141 meiotic telomere clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045141 bouquet biosynthesis|bouquet formation The cell cycle process in which the dynamic reorganization of telomeres occurs in early meiotic prophase, during which meiotic chromosome ends are gathered in a bouquet arrangement at the inner surface of the nuclear envelope proximal to the spindle pole body. This plays an important role in progression through meiosis and precedes synapsis. GO:0045142 triplex DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045142 Interacting selectively and non-covalently with a DNA triple helix. The formation of triple helical DNA has been evoked in several cellular processes including transcription, replication, and recombination. GO:1901639 XDP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901639 XDP catabolism|XDP degradation|XDP breakdown The chemical reactions and pathways resulting in the breakdown of XDP. GO:0045140 inositol phosphoceramide synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045140 MetaCyc:RXN3O-581|EC:2.7.1.227 IPC synthase activity Catalysis of the reaction: phytoceramide + inositol phosphate = inositol phosphoceramide + diacylglycerol. GO:1901637 obsolete positive regulation of maintenance of presynaptic active zone structure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901637 up regulation of maintenance of presynaptic active zone structure|upregulation of maintenance of presynaptic active zone structure|positive regulation of maintenance of presynaptic active zone structure|up-regulation of maintenance of presynaptic active zone structure|activation of maintenance of presynaptic active zone structure OBSOLETE. Any process that activates or increases the frequency, rate or extent of maintenance of presynaptic active zone structure. GO:1901638 obsolete copper ion import into ascospore-type prospore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901638 copper ion import into ascospore-type prospore|copper ion uptake in ascospore-type prospore OBSOLETE. Any copper ion import that takes place in ascospore-type prospore. GO:1901635 obsolete regulation of maintenance of presynaptic active zone structure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901635 regulation of maintenance of presynaptic active zone structure OBSOLETE. Any process that modulates the frequency, rate or extent of maintenance of presynaptic active zone structure. GO:1901636 obsolete negative regulation of maintenance of presynaptic active zone structure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901636 down-regulation of maintenance of presynaptic active zone structure|downregulation of maintenance of presynaptic active zone structure|down regulation of maintenance of presynaptic active zone structure|inhibition of maintenance of presynaptic active zone structure|negative regulation of maintenance of presynaptic active zone structure OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of presynaptic active zone structure. GO:1901633 negative regulation of synaptic vesicle membrane organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901633 down-regulation of synaptic vesicle membrane organisation|negative regulation of synaptic vesicle membrane organisation|down regulation of SLMV biogenesis|downregulation of SLMV biogenesis|down-regulation of synaptic vesicle membrane organization|downregulation of synaptic vesicle membrane organisation|down regulation of synaptic vesicle membrane organisation|negative regulation of SLMV biogenesis|down regulation of synaptic vesicle membrane organization and biogenesis|down-regulation of SLMV biogenesis|inhibition of synaptic vesicle membrane organisation|downregulation of synaptic vesicle membrane organization|downregulation of synaptic vesicle membrane organization and biogenesis|down regulation of synaptic vesicle membrane organization|inhibition of synaptic vesicle membrane organization|inhibition of SLMV biogenesis|down-regulation of synaptic vesicle membrane organization and biogenesis|negative regulation of synaptic vesicle membrane organization and biogenesis|inhibition of synaptic vesicle membrane organization and biogenesis Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle membrane organization. GO:0045149 acetoin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045149 acetoin metabolism The chemical reactions and pathways involving acetoin, 3-hydroxy-2-butanone, often as part of a fermentation pathway or for use as a carbon source. GO:1901634 positive regulation of synaptic vesicle membrane organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901634 upregulation of SLMV biogenesis|activation of synaptic vesicle membrane organization|up-regulation of synaptic vesicle membrane organization|up-regulation of synaptic vesicle membrane organization and biogenesis|positive regulation of synaptic vesicle membrane organisation|up regulation of synaptic vesicle membrane organisation|up regulation of SLMV biogenesis|positive regulation of SLMV biogenesis|upregulation of synaptic vesicle membrane organization and biogenesis|up regulation of synaptic vesicle membrane organization|activation of SLMV biogenesis|upregulation of synaptic vesicle membrane organisation|up-regulation of SLMV biogenesis|up regulation of synaptic vesicle membrane organization and biogenesis|positive regulation of synaptic vesicle membrane organization and biogenesis|upregulation of synaptic vesicle membrane organization|activation of synaptic vesicle membrane organisation|up-regulation of synaptic vesicle membrane organisation|activation of synaptic vesicle membrane organization and biogenesis Any process that activates or increases the frequency, rate or extent of synaptic vesicle membrane organization. GO:1901631 positive regulation of presynaptic membrane organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901631 upregulation of presynaptic membrane organisation|upregulation of presynaptic membrane organization|positive regulation of pre-synaptic membrane organization|up regulation of presynaptic membrane organisation|activation of presynaptic membrane organisation|positive regulation of presynaptic membrane organisation|up regulation of presynaptic membrane organization|activation of presynaptic membrane organization|up-regulation of presynaptic membrane organisation|up-regulation of presynaptic membrane organization Any process that activates or increases the frequency, rate or extent of presynaptic membrane organization. GO:0045147 regulation of initiation of acetate catabolic process by acetate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045147 regulation of initiation of acetate breakdown by acetate|regulation of initiation of acetate degradation by acetate Any process that modulates the activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate. GO:0045148 tripeptide aminopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045148 EC:3.4.11.4|MetaCyc:3.4.11.4-RXN alanine-phenylalanine-proline arylamidase activity|peptidase B|peptidase T|aminoexotripeptidase activity|imidoendopeptidase activity|lymphopeptidase activity|aminotripeptidase activity Catalysis of the hydrolysis of a single N-terminal amino acid residue from a tripeptide. GO:1901632 regulation of synaptic vesicle membrane organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901632 regulation of SLMV biogenesis|regulation of synaptic vesicle membrane organisation|regulation of synaptic vesicle membrane organization and biogenesis Any process that modulates the frequency, rate or extent of synaptic vesicle membrane organization. GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045145 single-stranded DNA specific 5'-3' exodeoxyribonuclease activity|ssDNA-specific 5'-3' exodeoxyribonuclease activity Catalysis of the sequential cleavage of nucleotides (such as mononucleotides or dinucleotides) from a free 5' terminus of a single-stranded DNA molecule. CHEBI:85375 N-acetylsphingosine 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85375 CHEBI:12427 N,N'-diacetylchitobiosyldiphosphodolichol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_12427 GO:1901630 negative regulation of presynaptic membrane organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901630 down regulation of presynaptic membrane organisation|negative regulation of pre-synaptic membrane organization|downregulation of presynaptic membrane organisation|down regulation of presynaptic membrane organization|downregulation of presynaptic membrane organization|negative regulation of presynaptic membrane organisation|down-regulation of presynaptic membrane organisation|inhibition of presynaptic membrane organisation|down-regulation of presynaptic membrane organization|inhibition of presynaptic membrane organization Any process that stops, prevents or reduces the frequency, rate or extent of presynaptic membrane organization. GO:0045146 initiation of acetate catabolic process by acetate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045146 initiation of acetate degradation by acetate|initiation of acetate breakdown by acetate The activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate. CHEBI:85376 N-octanoylsphingosine 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85376 GO:0045143 homologous chromosome segregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045143 meiosis I, chromosome segregation The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets. GO:0045144 meiotic sister chromatid segregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045144 meiosis II, chromosome segregation The cell cycle process in which sister chromatids are organized and then physically separated and randomly apportioned to two sets during the second division of the meiotic cell cycle. CHEBI:85378 N-oleoylsphingosine 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85378 GO:0060760 positive regulation of response to cytokine stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060760 Any process that increases the rate, frequency, or extent of a response to cytokine stimulus. GO:0060761 negative regulation of response to cytokine stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060761 Any process that decreases the rate, frequency, or extent of a response to cytokine stimulus. GO:0060762 regulation of branching involved in mammary gland duct morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060762 Any process that modulates the rate, frequency, or extent of branching involved in mammary gland duct morphogenesis. GO:0060763 mammary duct terminal end bud growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060763 The morphogenetic growth of the large, club-shaped terminal end of a mammary gland duct during prepubertal growth and during puberty. GO:0060764 cell-cell signaling involved in mammary gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060764 cell-cell signalling involved in mammary gland development Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mammary gland, from its initial state to the mature structure. UBERON:0013218 rete mirabile biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013218 red body|retie mirabilia|rete mirabilis|red gland|wonderful net|rete mirabilia A rete mirabile (Latin for 'wonderful net'; plural retia mirabilia) is a complex of arteries and veins lying very close to each other, found in some vertebrates. The rete mirabile utilizes countercurrent blood flow within the net (blood flowing in opposite directions. ) It exchanges heat, ions, or gases between vessel walls so that the two bloodstreams within the rete maintain a gradient with respect to temperature, or concentration of gases or solutes. GO:0060765 regulation of androgen receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060765 regulation of androgen receptor signalling pathway Any process that modulates the rate, frequency, or extent of the androgen receptor signaling pathway. GO:0060766 negative regulation of androgen receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060766 negative regulation of androgen receptor signalling pathway Any process that decreases the rate, frequency, or extent of the androgen receptor signaling pathway. GO:0060767 epithelial cell proliferation involved in prostate gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060767 The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time. GO:0060768 regulation of epithelial cell proliferation involved in prostate gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060768 Any process that modulates the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time. GO:0060769 positive regulation of epithelial cell proliferation involved in prostate gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060769 Any process that increases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time. GO:0045152 antisigma factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045152 antisigma factor antagonist activity Interacting selectively and non-covalently with an antisigma factor, a factor which inhibits the ability of the sigma factor to function as a transcriptional initiator. GO:0045153 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045153 GO:0045150 acetoin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045150 acetoin breakdown|acetoin catabolism|acetoin degradation The chemical reactions and pathways resulting in the breakdown of acetoin, 3-hydroxy-2-butanone. GO:0045151 acetoin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045151 acetoin anabolism|acetoin synthesis|acetoin formation|acetoin biosynthesis The chemical reactions and pathways resulting in the formation of acetoin, 3-hydroxy-2-butanone. GO:1901648 regulation of actomyosin contractile ring localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901648 regulation of contractile ring localization involved in cell cycle cytokinesis|regulation of contractile ring localisation involved in cell cycle cytokinesis Any process that modulates the frequency, rate or extent of actomyosin contractile ring localization. GO:1901649 negative regulation of actomyosin contractile ring localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901649 negative regulation of contractile ring localization involved in cell cycle cytokinesis|down-regulation of contractile ring localization involved in cell cycle cytokinesis|downregulation of actomyosin contractile ring localization|negative regulation of contractile ring localisation involved in cell cycle cytokinesis|down-regulation of contractile ring localisation involved in cell cycle cytokinesis|downregulation of contractile ring localization involved in cell cycle cytokinesis|down regulation of actomyosin contractile ring localization|inhibition of actomyosin contractile ring localization|down regulation of contractile ring localization involved in cell cycle cytokinesis|downregulation of contractile ring localisation involved in cell cycle cytokinesis|down regulation of contractile ring localisation involved in cell cycle cytokinesis|inhibition of contractile ring localization involved in cell cycle cytokinesis|inhibition of contractile ring localisation involved in cell cycle cytokinesis|down-regulation of actomyosin contractile ring localization Any process that stops, prevents or reduces the frequency, rate or extent of actomyosin contractile ring localization. GO:1901646 negative regulation of synoviocyte proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901646 inhibition of synoviocyte proliferation|down regulation of synoviocyte proliferation|downregulation of synoviocyte proliferation|down-regulation of synoviocyte proliferation Any process that stops, prevents or reduces the frequency, rate or extent of synoviocyte proliferation. GO:1901647 positive regulation of synoviocyte proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901647 up-regulation of synoviocyte proliferation|upregulation of synoviocyte proliferation|up regulation of synoviocyte proliferation|activation of synoviocyte proliferation Any process that activates or increases the frequency, rate or extent of synoviocyte proliferation. GO:1901644 obsolete positive regulation of tRNA methylation in response to nitrogen starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901644 upregulation of tRNA methylation in response to nitrogen starvation|up regulation of tRNA methylation in response to nitrogen starvation|activation of tRNA methylation in response to nitrogen starvation|up-regulation of tRNA methylation in response to nitrogen starvation OBSOLETE. Any process that activates or increases the frequency, rate or extent of tRNA methylation in response to nitrogen starvation. GO:1901645 regulation of synoviocyte proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901645 Any process that modulates the frequency, rate or extent of synoviocyte proliferation. GO:1901642 nucleoside transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901642 nucleoside membrane transport The directed movement of nucleoside across a membrane. GO:0045158 electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045158 cytochrome|cytochrome f|cytochrome b/b6|cytochrome b6 Enables the directed movement of electrons within the cytochrome b6/f complex of photosystem II. GO:1901643 obsolete regulation of tRNA methylation in response to nitrogen starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901643 OBSOLETE. Any process that modulates the frequency, rate or extent of tRNA methylation in response to nitrogen starvation. GO:0045159 myosin II binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045159 Interacting selectively and non-covalently with a class II myosin, any member of the class of 'conventional' double-headed myosins that includes muscle myosin. GO:0045156 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045156 cytochrome|cytochrome bc1 complex Enables the directed movement of electrons within the cyclic electron transport pathway of photosynthesis. GO:1901640 XTP binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901640 Interacting selectively and non-covalently with XTP. GO:1901641 ITP binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901641 Interacting selectively and non-covalently with ITP. GO:0045157 electron transporter, transferring electrons within the noncyclic electron transport pathway of photosynthesis activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045157 cytochrome Enables the directed movement of electrons within the noncyclic electron transport pathway of photosynthesis. GO:0060790 tooth placode formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060790 The developmental process in which the tooth placode forms. A tooth placode is a thickening of the ectoderm that will give rise to the tooth bud. GO:0045154 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045154 GO:0060791 sebaceous gland placode formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060791 The developmental process in which a sebaceous gland placode forms. A sebaceous gland placode is a thickening of the ectoderm that will give rise to the sebaceous gland bud. GO:0060792 sweat gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060792 The progression of the sweat gland over time, from its formation to the mature structure. Sweat glands secrete an aqueous solution that is used in thermoregulation. GO:0045155 obsolete electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045155 cytochrome|cytochrome c OBSOLETE. Enables the directed movement of electrons from the CoQH2-cytochrome c reductase complex and the cytochrome c oxidase complex. GO:0060793 sweat gland placode formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060793 The developmental process in which the sweat gland placode forms. An sweat gland placode is a thickening of the ectoderm that will give rise to the sweat gland bud. GO:0060794 leaflet morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060794 The process in which the anatomical structures of the leaflet are generated and organized. GO:0060795 cell fate commitment involved in formation of primary germ layer biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060795 The commitment of cells to specific cell fates of the endoderm, ectoderm, or mesoderm as a part of gastrulation. GO:0060796 obsolete regulation of transcription involved in primary germ layer cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060796 OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that results in cells adopting an endoderm, ectoderm or mesoderm cell fate. GO:0060797 transforming growth factor beta receptor signaling pathway involved in primary germ layer cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060797 transforming growth factor beta receptor signalling pathway involved in primary germ layer cell fate commitment A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to an unspecified cell adopting a mesoderm fate. GO:0060798 transforming growth factor beta receptor signaling pathway involved in mesodermal cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060798 transforming growth factor beta receptor signalling pathway involved in mesodermal cell fate specification The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands and ultimately resulting in the specification of a mesodermal fate. GO:0060799 transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060799 transforming growth factor beta receptor signalling pathway involved in endodermal cell fate specification The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands and ultimately resulting in the commitment of an unspecified fate to adopt an endoderm fate. GO:0070118 organellar chromatophore thylakoid membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070118 Paulinella-type chromatophore thylakoid membrane The lipid bilayer membrane of any thylakoid within an organellar chromatophore. GO:0070119 ciliary neurotrophic factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070119 CNTF binding Interacting selectively and non-covalently with the cytokine ciliary neurotrophic factor. GO:0070116 organellar chromatophore thylakoid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070116 Paulinella-type chromatophore thylakoid A thylakoid located in an organellar chromatophore. GO:0070117 organellar chromatophore thylakoid lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070117 Paulinella-type chromatophore thylakoid lumen The volume enclosed by an organellar chromatophore thylakoid membrane. GO:0070114 organellar chromatophore outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070114 Paulinella-type chromatophore outer membrane The outer, i.e. cytoplasm-facing, of the two lipid bilayers surrounding an organellar chromatophore. GO:0070115 organellar chromatophore intermembrane space biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070115 Paulinella-type chromatophore intermembrane space The region between the inner and outer lipid bilayers that surround an organellar chromatophore. GO:0070112 organellar chromatophore membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070112 Paulinella-type chromatophore membrane Either of the lipid bilayers that surround an organellar chromatophore. GO:0070113 organellar chromatophore inner membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070113 Paulinella-type chromatophore inner membrane The inner, i.e. lumen-facing, of the two lipid bilayers surrounding an organellar chromatophore. GO:0070110 ciliary neurotrophic factor receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070110 A protein complex that acts as a receptor for the cytokine ciliary neurotrophic factor (CNTF). In humans the receptor complex is a hexamer composed of two molecules each of CNTF and CNTFR and one molecule each of gp130 and LIFR. GO:0070111 organellar chromatophore biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070111 Paulinella-type chromatophore A bacteroid-containing symbiosome in which the bacterial component is a genetically highly reduced cyanobacterium that is photosynthetically active and incapable of an independent existence outside its host. The chromatophore functions as a photosynthetic organelle, and has been found and characterized in the amoeba Paulinella chromatophora. GO:0045163 clustering of voltage-gated potassium channels biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045163 voltage-gated potassium channel clustering|clustering of voltage-dependent potassium channels|Kv channel clustering|clustering of voltage gated potassium channels The process in which voltage-gated potassium channels become localized together in high densities. In animals, voltage-gated potassium (Kv) channels are clustered beneath the myelin sheath in regions immediately adjacent to paranodes, called juxtaparanodes, and along the inner mesaxon within the internode. GO:0045164 obsolete secretin (sensu Mammalia) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045164 secretin (sensu Mammalia) OBSOLETE. Secretin is a hormone that takes part in the digestion process. It also has effects on organs other than gastrointestinal tract. GO:0045161 neuronal ion channel clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045161 The process in which voltage-gated ion channels become localized to distinct subcellular domains in the neuron. Specific targeting, clustering, and maintenance of these channels in their respective domains are essential to achieve high conduction velocities of action potential propagation. GO:0045162 clustering of voltage-gated sodium channels biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045162 Nav channel clustering|clustering of voltage gated sodium channels|clustering of voltage-dependent sodium channels|voltage-gated sodium channel clustering The process in which voltage-gated sodium channels become localized together in high densities. In animals, nodes of Ranvier differ dramatically from internodal axonal regions in very high densities of voltage-dependent sodium (Nav) channels responsible for the rapid, inward ionic currents that produce membrane depolarization. GO:1901659 glycosyl compound biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901659 glycosyl compound biosynthesis|glycosyl compound anabolism|glycosyl compound synthesis|glycosyl compound formation The chemical reactions and pathways resulting in the formation of glycosyl compound. GO:0045160 myosin I complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045160 A myosin complex containing a class I myosin heavy chain and associated light chains; myosin I heavy chains are single-headed, possess tails of various lengths, and do not self-associate into bipolar filaments; myosin I complexes are involved in diverse processes related to membrane traffic and cell movement. UBERON:0013280 diaphysis of tibia biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013280 body of the tibia|shaft of tibia|tibial diaphysis|shaft of tibia|body of tibia|corpus tibiae A diaphysis that is part of a tibia. GO:1901657 glycosyl compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901657 glycosyl compound metabolism The chemical reactions and pathways involving glycosyl compound. GO:1901658 glycosyl compound catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901658 glycosyl compound degradation|glycosyl compound catabolism|glycosyl compound breakdown The chemical reactions and pathways resulting in the breakdown of glycosyl compound. GO:1901655 cellular response to ketone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901655 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ketone stimulus. GO:1901656 glycoside transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901656 The directed movement of a glycoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:1901653 cellular response to peptide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901653 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus. GO:0045169 fusome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045169 A large intracellular spectrin-rich structure that has been found in insect germline cells and mammalian hematopoietic cells. The fusome is an elongated, branched structure, formed from the spherical spectrosome organelle. GO:1901654 response to ketone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901654 process resulting in tolerance to ketone A response that results in a state of tolerance to ketone. GO:0045167 asymmetric protein localization involved in cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045167 asymmetric protein localisation involved in cell fate determination|asymmetric protein localization involved in cell fate commitment|asymmetric protein localization resulting in cell fate commitment|cell fate commitment, asymmetric protein localization Any process in which a protein is transported to, or maintained in, a specific asymmetric distribution, resulting in the formation of daughter cells of different types. GO:1901651 regulation of mitotic chromosome decondensation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901651 Any process that modulates the frequency, rate or extent of mitotic chromosome decondensation. GO:0045168 cell-cell signaling involved in cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045168 cell-cell signaling resulting in cell fate commitment|cell fate commitment, cell-cell signalling|cell-cell signalling involved in cell fate specification|cell fate commitment, cell-cell signaling|cell-cell signaling during in cell fate commitment|cell-cell signalling resulting in cell fate commitment|cell-cell signalling during cell fate commitment Signaling at long or short range between cells that results in the commitment of a cell to a certain fate. GO:1901652 response to peptide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901652 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus. GO:0060780 intercalary leaflet morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060780 The process in which the intercalary leaflet attains its shape. An intercalary leaflet is a leaflet that develops between primary leaflets. GO:0045165 cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045165 The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. GO:1901650 positive regulation of actomyosin contractile ring localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901650 up-regulation of actomyosin contractile ring localization|activation of actomyosin contractile ring localization|upregulation of contractile ring localisation involved in cell cycle cytokinesis|up-regulation of contractile ring localization involved in cell cycle cytokinesis|activation of contractile ring localization involved in cell cycle cytokinesis|up-regulation of contractile ring localisation involved in cell cycle cytokinesis|up regulation of actomyosin contractile ring localization|positive regulation of contractile ring localization involved in cell cycle cytokinesis|up regulation of contractile ring localization involved in cell cycle cytokinesis|activation of contractile ring localisation involved in cell cycle cytokinesis|positive regulation of contractile ring localisation involved in cell cycle cytokinesis|upregulation of actomyosin contractile ring localization|up regulation of contractile ring localisation involved in cell cycle cytokinesis|upregulation of contractile ring localization involved in cell cycle cytokinesis Any process that activates or increases the frequency, rate or extent of actomyosin contractile ring localization. GO:0060781 mesenchymal cell proliferation involved in prostate gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060781 The multiplication or reproduction of mesenchymal cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time. GO:0045166 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045166 GO:0060782 regulation of mesenchymal cell proliferation involved in prostate gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060782 Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the prostate gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. GO:0060783 mesenchymal smoothened signaling pathway involved in prostate gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060783 mesenchymal hh signaling pathway involved in prostate gland development|mesenchymal smoothened signalling pathway involved in prostate gland development|mesenchymal hedgehog signaling pathway involved in prostate gland development The series of molecular signals generated as a consequence of activation of the transmembrane Smoothened-type protein in the mesenchymal cells of the prostate that contribute to the progression of the prostate over time. This process contributes to lung development. GO:0060784 regulation of cell proliferation involved in tissue homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060784 Any process that modulates the frequency, rate or extent of cell proliferation resulting in the maintenance of a steady-state number of cells within a tissue. GO:0060785 regulation of apoptosis involved in tissue homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060785 Any process that modulates the occurrence or rate of cell death by apoptosis that results in the maintenance of the steady-state number of cells within a tissue. GO:0070109 positive regulation of interleukin-27-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070109 positive regulation of interleukin-27-mediated signalling pathway|positive regulation of IL27RA/IL6ST signaling pathway|positive regulation of IL-27-mediated signaling pathway Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-27 binding to a cell surface receptor. GO:0060786 regulation of cell differentiation involved in tissue homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060786 Any process that modulates the frequency, rate or extent of cell differentiation that contributes to the maintenance of a steady state of a cell type within a tissue. GO:0060787 positive regulation of posterior neural plate formation by fibroblast growth factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060787 positive regulation of posterior neural plate formation by FGF receptor signaling pathway|positive regulation of posterior neural plate formation by fibroblast growth factor receptor signalling pathway Any process that increases the rate or extent of the formation of the posterior neural plate, the posterior end of the flat, thickened layer of ectodermal cells known as the neural plate. GO:0060788 ectodermal placode formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060788 The developmental process in which an ectodermal placode forms. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm. GO:0070107 regulation of interleukin-27-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070107 regulation of IL27RA/IL6ST signaling pathway|regulation of IL-27-mediated signaling pathway|regulation of interleukin-27-mediated signalling pathway Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-27-mediated binding to a cell surface receptor. GO:0060789 hair follicle placode formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060789 The developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud. GO:0070108 negative regulation of interleukin-27-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070108 negative regulation of IL27RA/IL6ST signaling pathway|negative regulation of IL-27-mediated signaling pathway|negative regulation of interleukin-27-mediated signalling pathway Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-27 binding to a cell surface receptor. GO:0070105 positive regulation of interleukin-6-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070105 positive regulation of IL-6-mediated signaling pathway|positive regulation of interleukin-6-mediated signalling pathway Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-6 binding to a cell surface receptor. GO:0070106 interleukin-27-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070106 IL27RA/IL6ST signaling pathway|IL-27-mediated signaling pathway|interleukin-27-mediated signalling pathway A series of molecular signals initiated by the binding of interleukin-27 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0070103 regulation of interleukin-6-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070103 regulation of IL-6-mediated signaling pathway|regulation of interleukin-6-mediated signalling pathway Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-6-mediated binding to a cell surface receptor. GO:0070104 negative regulation of interleukin-6-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070104 negative regulation of interleukin-6-mediated signalling pathway|negative regulation of IL-6-mediated signaling pathway Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-6 binding to a cell surface receptor. GO:0070101 positive regulation of chemokine-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070101 positive regulation of chemokine-mediated signalling pathway Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of a chemokine binding to a cell surface receptor. GO:0070102 interleukin-6-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070102 interleukin-6-mediated signalling pathway|IL-6-mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-6 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0070100 negative regulation of chemokine-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070100 negative regulation of chemokine-mediated signalling pathway Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of a chemokine binding to a cell surface receptor. GO:0045174 glutathione dehydrogenase (ascorbate) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045174 Reactome:R-HSA-198813|KEGG_REACTION:R01108|MetaCyc:1.8.5.1-RXN|RHEA:24424|EC:1.8.5.1 glutathione:dehydroascorbate oxidoreductase activity|dehydroascorbic reductase activity|dehydroascorbate reductase activity|DHA reductase activity|glutathione:dehydroascorbic acid oxidoreductase activity|dehydroascorbic acid reductase activity|glutathione dehydroascorbate reductase activity|GDOR Catalysis of the reaction: dehydroascorbate + 2 glutathione = L-ascorbate + glutathione disulfide. GO:0070130 negative regulation of mitochondrial translation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070130 negative regulation of mitochondrial protein anabolism|negative regulation of mitochondrial protein synthesis|negative regulation of mitochondrial protein formation|negative regulation of mitochondrial protein biosynthesis Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion. GO:0045175 basal protein localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045175 establishment and maintenance of basal protein localization|basal protein localisation|establishment and maintenance of protein localization in basal part of cell Any process in which a protein is transported to, or maintained in, basal regions of the cell. GO:0070131 positive regulation of mitochondrial translation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070131 positive regulation of mitochondrial protein anabolism|positive regulation of mitochondrial protein synthesis|positive regulation of mitochondrial protein formation|positive regulation of mitochondrial protein biosynthesis Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion. GO:0045172 germline ring canal biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045172 Germline specific intercellular bridge. During cyst formation in insects, ring canals interconnect the cells of the cyst, facilitating the passage of cytoplasmic components between cells. GO:0045173 O-sialoglycoprotein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045173 O-sialoglycoprotein catabolism|O-sialoglycoprotein degradation|O-sialoglycoprotein breakdown The chemical reactions and pathways resulting in the breakdown of O-sialoglycoproteins, glycoproteins which contain sialic acid as one of their carbohydrates. They are often found on or in the cell or tissue membranes and participate in a variety of biological activities. GO:0045170 spectrosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045170 A germline specific spherical organelle, rich in membrane skeletal proteins. Precursor to the fusome. GO:0045171 intercellular bridge biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045171 A direct connection between the cytoplasm of two cells that is formed following the completion of cleavage furrow ingression during cell division. They are usually present only briefly prior to completion of cytokinesis. However, in some cases, such as the bridges between germ cells during their development, they become stabilised. GO:1901668 regulation of superoxide dismutase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901668 regulation of zinc superoxide oxidoreductase|regulation of hemocuprein|regulation of copper, zinc superoxide dismutase activity|regulation of cuprein|regulation of Mn, Fe superoxide dismutase|regulation of SODS|regulation of nickel superoxide dismutase activity|regulation of SOD-4|regulation of Cu-Zn superoxide dismutase activity|regulation of SOD-3|regulation of iron superoxide dismutase activity|regulation of hepatocuprein|regulation of SOD-2|regulation of SOD-1|regulation of superoxide dismutase I|regulation of manganese superoxide oxidoreductase|regulation of Cu,Zn-SOD|regulation of SOD|regulation of superoxide dismutase II|regulation of cytocuprein|regulation of SODF|regulation of Mn-SOD|regulation of Fe-SOD|regulation of erythrocuprein|regulation of nickel superoxide oxidoreductase|regulation of manganese superoxide dismutase activity|regulation of ferrisuperoxide dismutase activity|regulation of iron superoxide oxidoreductase|regulation of superoxide:superoxide oxidoreductase activity Any process that modulates the frequency, rate or extent of superoxide dismutase activity. GO:1901666 positive regulation of NAD+ ADP-ribosyltransferase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901666 up-regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|positive regulation of NAD ADP-ribosyltransferase activity|activation of poly(ADP-ribose) synthetase activity|upregulation of poly(ADP-ribose) synthase activity|up-regulation of ADP-ribosyltransferase (polymerizing) activity|up regulation of poly(ADP-ribose)polymerase activity|activation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|activation of NAD ADP-ribosyltransferase activity|up regulation of NAD+ ADP-ribosyltransferase activity|positive regulation of poly(ADP-ribose)polymerase activity|positive regulation of poly(ADP-ribose) synthetase activity|upregulation of poly(adenosine diphosphate ribose) polymerase activity|positive regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|up regulation of poly(ADP-ribose) synthetase activity|activation of ADP-ribosyltransferase (polymerizing) activity|up-regulation of NAD ADP-ribosyltransferase activity|up regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|up-regulation of poly(ADP-ribose) synthase activity|activation of poly(ADP-ribose)polymerase activity|positive regulation of ADP-ribosyltransferase (polymerizing) activity|upregulation of NAD+ ADP-ribosyltransferase activity|up-regulation of poly(adenosine diphosphate ribose) polymerase activity|up regulation of ADP-ribosyltransferase (polymerizing) activity|activation of poly(ADP-ribose) synthase activity|up-regulation of poly(ADP-ribose)polymerase activity|upregulation of poly(ADP-ribose) synthetase activity|upregulation of NAD ADP-ribosyltransferase activity|upregulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|positive regulation of poly(ADP-ribose) synthase activity|activation of poly(adenosine diphosphate ribose) polymerase activity|activation of NAD+ ADP-ribosyltransferase activity|up-regulation of NAD+ ADP-ribosyltransferase activity|up regulation of poly(ADP-ribose) synthase activity|upregulation of ADP-ribosyltransferase (polymerizing) activity|upregulation of poly(ADP-ribose)polymerase activity|positive regulation of poly(adenosine diphosphate ribose) polymerase activity|up-regulation of poly(ADP-ribose) synthetase activity|up regulation of NAD ADP-ribosyltransferase activity|up regulation of poly(adenosine diphosphate ribose) polymerase activity Any process that activates or increases the frequency, rate or extent of NAD+ ADP-ribosyltransferase activity. UBERON:0013279 diaphysis of fibula biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013279 body of fibula|shaft of fibula|fibula diaphysis|corpus fibulae A diaphysis that is part of a fibula[Automatically generated definition]. GO:1901667 negative regulation of skeletal muscle satellite cell activation involved in skeletal muscle regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901667 downregulation of satellite cell activation involved in skeletal muscle regeneration|down regulation of satellite cell activation involved in skeletal muscle regeneration|inhibition of satellite cell activation involved in skeletal muscle regeneration|down-regulation of satellite cell activation involved in skeletal muscle regeneration Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell activation involved in skeletal muscle regeneration. GO:1901664 regulation of NAD+ ADP-ribosyltransferase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901664 regulation of poly(ADP-ribose)polymerase activity|regulation of poly(adenosine diphosphate ribose) polymerase activity|regulation of poly(ADP-ribose) synthetase activity|regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|regulation of ADP-ribosyltransferase (polymerizing) activity|regulation of NAD ADP-ribosyltransferase activity|regulation of poly(ADP-ribose) synthase activity Any process that modulates the frequency, rate or extent of NAD+ ADP-ribosyltransferase activity. GO:1901665 negative regulation of NAD+ ADP-ribosyltransferase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901665 down regulation of poly(ADP-ribose) synthase activity|downregulation of poly(adenosine diphosphate ribose) polymerase activity|downregulation of poly(ADP-ribose)polymerase activity|negative regulation of poly(ADP-ribose) synthetase activity|negative regulation of NAD ADP-ribosyltransferase activity|down-regulation of NAD ADP-ribosyltransferase activity|down-regulation of poly(ADP-ribose) synthetase activity|down regulation of poly(adenosine diphosphate ribose) polymerase activity|down-regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|negative regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|inhibition of poly(ADP-ribose) synthase activity|downregulation of NAD+ ADP-ribosyltransferase activity|down-regulation of ADP-ribosyltransferase (polymerizing) activity|down-regulation of poly(ADP-ribose)polymerase activity|negative regulation of ADP-ribosyltransferase (polymerizing) activity|negative regulation of poly(ADP-ribose)polymerase activity|inhibition of poly(adenosine diphosphate ribose) polymerase activity|down regulation of NAD+ ADP-ribosyltransferase activity|downregulation of poly(ADP-ribose) synthetase activity|inhibition of NAD+ ADP-ribosyltransferase activity|downregulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|inhibition of NAD ADP-ribosyltransferase activity|down regulation of poly(ADP-ribose) synthetase activity|down-regulation of poly(ADP-ribose) synthase activity|down regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|negative regulation of poly(ADP-ribose) synthase activity|downregulation of ADP-ribosyltransferase (polymerizing) activity|down regulation of NAD ADP-ribosyltransferase activity|inhibition of poly(ADP-ribose)polymerase activity|down regulation of ADP-ribosyltransferase (polymerizing) activity|negative regulation of poly(adenosine diphosphate ribose) polymerase activity|inhibition of poly(ADP-ribose) synthetase activity|down-regulation of poly(adenosine diphosphate ribose) polymerase activity|inhibition of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|downregulation of NAD ADP-ribosyltransferase activity|downregulation of poly(ADP-ribose) synthase activity|down regulation of poly(ADP-ribose)polymerase activity|inhibition of ADP-ribosyltransferase (polymerizing) activity|down-regulation of NAD+ ADP-ribosyltransferase activity Any process that stops, prevents or reduces the frequency, rate or extent of NAD+ ADP-ribosyltransferase activity. GO:1901662 quinone catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901662 quinone breakdown|quinone cofactor catabolism|quinone catabolism|quinone cofactor degradation|quinone cofactor breakdown|quinone cofactor catabolic process|quinone degradation The chemical reactions and pathways resulting in the breakdown of quinone. GO:0045178 basal part of cell biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0045178 The region of a cell situated near the base. For example, in a polarized epithelial cell, the basal surface rests on the basal lamina that separates the epithelium from other tissue. GO:0045179 apical cortex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045179 The region that lies just beneath the plasma membrane on the apical edge of a cell. GO:1901663 quinone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901663 quinone cofactor synthesis|quinone cofactor formation|quinone cofactor biosynthesis|quinone cofactor biosynthetic process|quinone anabolism|quinone synthesis|quinone biosynthesis|quinone formation|quinone cofactor anabolism The chemical reactions and pathways resulting in the formation of quinone. GO:0045176 apical protein localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045176 establishment and maintenance of apical protein localization|establishment and maintenance of protein localization in apical part of cell|apical protein localisation Any process in which a protein is transported to, or maintained in, apical regions of the cell. GO:1901660 calcium ion export biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901660 The directed movement of calcium ion out of a cell or organelle. GO:1901661 quinone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901661 quinone cofactor metabolism|quinone metabolism|quinone cofactor metabolic process The chemical reactions and pathways involving quinone. GO:0045177 apical part of cell biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0045177 apical region of cell The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue. GO:1901670 negative regulation of superoxide dismutase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901670 down-regulation of SOD-4|negative regulation of SOD-4|downregulation of Mn-SOD|inhibition of superoxide:superoxide oxidoreductase activity|inhibition of manganese superoxide dismutase activity|down-regulation of SOD-3|negative regulation of SOD-3|inhibition of iron superoxide dismutase activity|downregulation of superoxide dismutase II|downregulation of cytocuprein|down-regulation of SOD-2|negative regulation of SOD-2|down-regulation of Cu-Zn superoxide dismutase activity|down-regulation of zinc superoxide oxidoreductase|downregulation of Fe-SOD|down regulation of SODF|down-regulation of hepatocuprein|negative regulation of Cu-Zn superoxide dismutase activity|negative regulation of zinc superoxide oxidoreductase|negative regulation of hepatocuprein|down-regulation of SOD-1|negative regulation of SOD-1|inhibition of superoxide dismutase I|downregulation of erythrocuprein|negative regulation of copper, zinc superoxide dismutase activity|down regulation of Mn-SOD|down-regulation of copper, zinc superoxide dismutase activity|inhibition of hemocuprein|inhibition of cuprein|negative regulation of manganese superoxide oxidoreductase|downregulation of nickel superoxide oxidoreductase|down-regulation of manganese superoxide oxidoreductase|down regulation of Fe-SOD|negative regulation of Cu,Zn-SOD|down-regulation of Cu,Zn-SOD|downregulation of iron superoxide oxidoreductase|negative regulation of SOD|down-regulation of SOD|down regulation of erythrocuprein|down regulation of manganese superoxide dismutase activity|down regulation of superoxide:superoxide oxidoreductase activity|down-regulation of SODS|downregulation of ferrisuperoxide dismutase activity|negative regulation of SODS|inhibition of SODF|down regulation of superoxide dismutase activity|down regulation of nickel superoxide oxidoreductase|inhibition of Mn, Fe superoxide dismutase|down-regulation of cytocuprein|down-regulation of superoxide dismutase II|negative regulation of superoxide dismutase II|negative regulation of cytocuprein|downregulation of superoxide:superoxide oxidoreductase activity|down regulation of iron superoxide oxidoreductase|inhibition of Mn-SOD|downregulation of zinc superoxide oxidoreductase|down-regulation of nickel superoxide dismutase activity|down regulation of hemocuprein|downregulation of manganese superoxide dismutase activity|negative regulation of nickel superoxide dismutase activity|down regulation of ferrisuperoxide dismutase activity|inhibition of SOD-4|down regulation of cuprein|negative regulation of iron superoxide dismutase activity|downregulation of superoxide dismutase activity|inhibition of SOD-3|downregulation of copper, zinc superoxide dismutase activity|down-regulation of iron superoxide dismutase activity|inhibition of Fe-SOD|inhibition of SOD-2|inhibition of hepatocuprein|inhibition of erythrocuprein|inhibition of Cu-Zn superoxide dismutase activity|downregulation of hemocuprein|down regulation of zinc superoxide oxidoreductase|inhibition of SOD-1|negative regulation of superoxide dismutase I|down-regulation of superoxide dismutase I|downregulation of cuprein|inhibition of nickel superoxide oxidoreductase|downregulation of SODS|down regulation of copper, zinc superoxide dismutase activity|inhibition of manganese superoxide oxidoreductase|down regulation of Mn, Fe superoxide dismutase|inhibition of iron superoxide oxidoreductase|inhibition of Cu,Zn-SOD|inhibition of SOD|inhibition of ferrisuperoxide dismutase activity|down regulation of SOD-4|negative regulation of superoxide:superoxide oxidoreductase activity|down-regulation of manganese superoxide dismutase activity|down-regulation of superoxide:superoxide oxidoreductase activity|down regulation of SOD-3|downregulation of nickel superoxide dismutase activity|negative regulation of manganese superoxide dismutase activity|down regulation of Cu-Zn superoxide dismutase activity|down-regulation of SODF|downregulation of Mn, Fe superoxide dismutase|down regulation of SODS|down regulation of SOD-2|negative regulation of SODF|down regulation of hepatocuprein|inhibition of superoxide dismutase II|down-regulation of superoxide dismutase activity|down regulation of SOD-1|downregulation of iron superoxide dismutase activity|inhibition of cytocuprein|inhibition of zinc superoxide oxidoreductase|down-regulation of Mn-SOD|negative regulation of Mn-SOD|downregulation of SOD-4|down regulation of nickel superoxide dismutase activity|down regulation of manganese superoxide oxidoreductase|downregulation of superoxide dismutase I|down-regulation of hemocuprein|negative regulation of hemocuprein|downregulation of SOD-3|inhibition of copper, zinc superoxide dismutase activity|down regulation of Cu,Zn-SOD|negative regulation of Fe-SOD|downregulation of hepatocuprein|negative regulation of cuprein|down-regulation of cuprein|down-regulation of Fe-SOD|downregulation of SOD-2|downregulation of Cu-Zn superoxide dismutase activity|down regulation of SOD|down regulation of iron superoxide dismutase activity|negative regulation of erythrocuprein|downregulation of SOD-1|down-regulation of erythrocuprein|negative regulation of nickel superoxide oxidoreductase|inhibition of SODS|downregulation of manganese superoxide oxidoreductase|down-regulation of nickel superoxide oxidoreductase|down regulation of superoxide dismutase I|inhibition of superoxide dismutase activity|downregulation of Cu,Zn-SOD|down regulation of cytocuprein|down regulation of superoxide dismutase II|downregulation of SOD|down-regulation of Mn, Fe superoxide dismutase|downregulation of SODF|down-regulation of iron superoxide oxidoreductase|negative regulation of iron superoxide oxidoreductase|negative regulation of Mn, Fe superoxide dismutase|inhibition of nickel superoxide dismutase activity|negative regulation of ferrisuperoxide dismutase activity|down-regulation of ferrisuperoxide dismutase activity Any process that stops, prevents or reduces the frequency, rate or extent of superoxide dismutase activity. GO:0070138 ubiquitin-like protein-specific isopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070138 small conjugating protein-specific isopeptidase activity Catalysis of the hydrolysis of an isopeptide bond between a small protein such as ubiquitin or a ubiquitin-like protein (e.g. APG8, ISG15, NEDD8, SUMO) and a protein to which the small protein has been conjugated. GO:0070139 SUMO-specific endopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070139 Reactome:R-HSA-2990842|Reactome:R-HSA-2990840|Reactome:R-HSA-2993763 Catalysis of the hydrolysis of peptide bonds between an alpha-carboxyl group and an alpha-amino group within the small conjugating protein SUMO. GO:0070136 beta-1,2-oligomannoside biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070136 beta-1,2-oligomannoside anabolism|beta-1,2-oligomannoside synthesis|beta-1,2-oligomannoside formation|beta-1,2-oligomannoside biosynthesis The chemical reactions and pathways resulting in the formation of beta-1,2-linked oligomannosides, which are found in fungal cell wall phosphopeptidomannan and phospholipomannan. GO:0070137 ubiquitin-like protein-specific endopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070137 small conjugating protein-specific endopeptidase activity Catalysis of the hydrolysis of peptide bonds between an alpha-carboxyl group and an alpha-amino group within a small protein such as ubiquitin or a ubiquitin-like protein (e.g. APG8, ISG15, NEDD8, SUMO). GO:0070134 positive regulation of mitochondrial translational initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070134 positive regulation of mitochondrial translation initiation Any process that activates or increases the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. GO:0070135 beta-1,2-oligomannoside metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070135 beta-1,2-oligomannoside metabolism The chemical reactions and pathways involving beta-1,2-linked oligomannosides, which are found in fungal cell wall phosphopeptidomannan and phospholipomannan. GO:0070132 regulation of mitochondrial translational initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070132 regulation of mitochondrial translation initiation Any process that modulates the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. GO:0070133 negative regulation of mitochondrial translational initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070133 negative regulation of mitochondrial translation initiation Any process that stops, prevents, or reduces the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. GO:0045185 maintenance of protein location biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045185 protein sequestering|protein retention|active protein retrieval|maintenance of protein localization Any process in which a protein is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of proteins that do move away. GO:0045186 zonula adherens assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045186 Assembly of the zonula adherens, a cell-cell adherens junction which forms a continuous belt near the apex of epithelial cells. GO:0070120 ciliary neurotrophic factor-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070120 CNTF-mediated signaling pathway|ciliary neurotrophic factor-mediated signalling pathway A series of molecular signals initiated by the binding of a ciliary neurotrophic factor (CNTF) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0045183 translation factor activity, non-nucleic acid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045183 A translation regulator activity that does not involve binding to nucleic acids. GO:0045184 establishment of protein localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045184 protein recruitment|protein positioning|establishment of protein localisation The directed movement of a protein to a specific location. GO:0045181 glutamate synthase activity, NAD(P)H as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045181 glutamate synthase activity, NADH or NADPH as acceptor Catalysis of the reaction: 2 L-glutamate + NAD(P)+ = L-glutamine + 2-oxoglutarate + NAD(P)H + H+. GO:0045182 translation regulator activity biolink:MolecularActivity go-plus goslim_candida|goslim_pir|goslim_plant|goslim_drosophila|goslim_aspergillus http://purl.obolibrary.org/obo/GO_0045182 translation factor activity Any molecular function involved in the initiation, activation, perpetuation, repression or termination of polypeptide synthesis at the ribosome. GO:1901679 nucleotide transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901679 nucleotide membrane transport The directed movement of nucleotide across a membrane. GO:0045180 basal cortex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045180 The region that lies just beneath the plasma membrane on the basal edge of a cell. GO:1901677 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1901677 GO:1901678 iron coordination entity transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901678 The directed movement of an iron coordination entity into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:1901675 negative regulation of histone H3-K27 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901675 down-regulation of histone H3 acetylation at K27|negative regulation of histone H3 acetylation at K27|down regulation of histone H3-K27 acetylation|inhibition of histone H3-K27 acetylation|down regulation of histone H3K27 acetylation|downregulation of histone H3K27 acetylation|inhibition of histone H3 acetylation at K27|negative regulation of histone H3K27 acetylation|down-regulation of histone H3K27 acetylation|down regulation of histone H3 acetylation at K27|down-regulation of histone H3-K27 acetylation|downregulation of histone H3 acetylation at K27|inhibition of histone H3K27 acetylation|downregulation of histone H3-K27 acetylation Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K27 acetylation. GO:1901676 positive regulation of histone H3-K27 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901676 activation of histone H3 acetylation at K27|upregulation of histone H3K27 acetylation|upregulation of histone H3-K27 acetylation|up-regulation of histone H3 acetylation at K27|up regulation of histone H3K27 acetylation|positive regulation of histone H3K27 acetylation|up-regulation of histone H3-K27 acetylation|activation of histone H3-K27 acetylation|upregulation of histone H3 acetylation at K27|activation of histone H3K27 acetylation|up-regulation of histone H3K27 acetylation|up regulation of histone H3-K27 acetylation|up regulation of histone H3 acetylation at K27|positive regulation of histone H3 acetylation at K27 Any process that activates or increases the frequency, rate or extent of histone H3-K27 acetylation. GO:0045189 obsolete connective tissue growth factor biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045189 connective tissue growth factor synthesis|connective tissue growth factor formation|connective tissue growth factor biosynthesis|CTGF biosynthesis|connective tissue growth factor anabolism OBSOLETE. The chemical reactions and pathways resulting in the formation of CTGF, produced by human umbilical vein endothelial cells and by skin fibroblasts after activation with TGF-beta. GO:1901673 regulation of mitotic spindle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901673 regulation of spindle assembly involved in mitosis Any process that modulates the frequency, rate or extent of mitotic spindle assembly. GO:1901674 regulation of histone H3-K27 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901674 regulation of histone H3K27 acetylation|regulation of histone H3 acetylation at K27 Any process that modulates the frequency, rate or extent of histone H3-K27 acetylation. GO:1901671 positive regulation of superoxide dismutase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901671 positive regulation of nickel superoxide oxidoreductase|up regulation of erythrocuprein|up regulation of Cu,Zn-SOD|up-regulation of cuprein|up-regulation of SODS|up regulation of SOD|activation of SOD-4|activation of zinc superoxide oxidoreductase|positive regulation of manganese superoxide oxidoreductase|positive regulation of Cu,Zn-SOD|up regulation of nickel superoxide oxidoreductase|activation of SOD-3|positive regulation of iron superoxide oxidoreductase|positive regulation of ferrisuperoxide dismutase activity|activation of SOD-2|activation of copper, zinc superoxide dismutase activity|activation of hepatocuprein|activation of Cu-Zn superoxide dismutase activity|positive regulation of SOD|up regulation of iron superoxide oxidoreductase|upregulation of manganese superoxide dismutase activity|activation of SOD-1|up-regulation of nickel superoxide dismutase activity|up regulation of cytocuprein|up regulation of superoxide dismutase II|upregulation of superoxide:superoxide oxidoreductase activity|up regulation of ferrisuperoxide dismutase activity|upregulation of SODF|up-regulation of Mn, Fe superoxide dismutase|positive regulation of superoxide dismutase II|positive regulation of cytocuprein|activation of manganese superoxide oxidoreductase|up-regulation of iron superoxide dismutase activity|positive regulation of zinc superoxide oxidoreductase|up-regulation of SOD-4|activation of Cu,Zn-SOD|upregulation of superoxide dismutase activity|activation of SODS|upregulation of Mn-SOD|activation of SOD|up-regulation of SOD-3|upregulation of hemocuprein|positive regulation of copper, zinc superoxide dismutase activity|up-regulation of superoxide dismutase I|up regulation of zinc superoxide oxidoreductase|up-regulation of Cu-Zn superoxide dismutase activity|upregulation of cuprein|up-regulation of SOD-2|up-regulation of hepatocuprein|upregulation of Fe-SOD|up-regulation of SOD-1|up regulation of copper, zinc superoxide dismutase activity|activation of nickel superoxide dismutase activity|upregulation of erythrocuprein|activation of cytocuprein|activation of superoxide dismutase II|up-regulation of manganese superoxide oxidoreductase|activation of iron superoxide dismutase activity|upregulation of nickel superoxide oxidoreductase|positive regulation of SODS|up-regulation of Cu,Zn-SOD|upregulation of iron superoxide oxidoreductase|up-regulation of SODF|up-regulation of SOD|activation of superoxide dismutase I|up regulation of manganese superoxide dismutase activity|upregulation of Mn, Fe superoxide dismutase|up regulation of SODS|positive regulation of nickel superoxide dismutase activity|up regulation of superoxide:superoxide oxidoreductase activity|upregulation of ferrisuperoxide dismutase activity|up-regulation of Mn-SOD|positive regulation of manganese superoxide dismutase activity|upregulation of SOD-4|up regulation of superoxide dismutase activity|upregulation of SOD-3|up-regulation of cytocuprein|positive regulation of superoxide:superoxide oxidoreductase activity|positive regulation of iron superoxide dismutase activity|up regulation of nickel superoxide dismutase activity|up-regulation of superoxide dismutase II|up regulation of hemocuprein|activation of superoxide dismutase activity|upregulation of SOD-2|up-regulation of Fe-SOD|upregulation of hepatocuprein|upregulation of zinc superoxide oxidoreductase|upregulation of Cu-Zn superoxide dismutase activity|upregulation of SOD-1|up regulation of iron superoxide dismutase activity|up-regulation of erythrocuprein|up regulation of cuprein|positive regulation of superoxide dismutase I|positive regulation of hemocuprein|activation of SODF|upregulation of copper, zinc superoxide dismutase activity|positive regulation of cuprein|activation of manganese superoxide dismutase activity|upregulation of manganese superoxide oxidoreductase|up-regulation of nickel superoxide oxidoreductase|up regulation of superoxide dismutase I|activation of Mn-SOD|upregulation of Cu,Zn-SOD|activation of superoxide:superoxide oxidoreductase activity|upregulation of SOD|up-regulation of iron superoxide oxidoreductase|up regulation of Mn, Fe superoxide dismutase|upregulation of SODS|activation of Fe-SOD|up-regulation of ferrisuperoxide dismutase activity|positive regulation of SODF|activation of erythrocuprein|activation of hemocuprein|upregulation of superoxide dismutase II|positive regulation of Mn, Fe superoxide dismutase|upregulation of cytocuprein|up regulation of SOD-4|activation of cuprein|activation of nickel superoxide oxidoreductase|positive regulation of Mn-SOD|up-regulation of manganese superoxide dismutase activity|upregulation of nickel superoxide dismutase activity|up regulation of SOD-3|up-regulation of zinc superoxide oxidoreductase|up regulation of SODF|up-regulation of superoxide:superoxide oxidoreductase activity|up regulation of Cu-Zn superoxide dismutase activity|up regulation of SOD-2|positive regulation of SOD-4|up regulation of hepatocuprein|upregulation of iron superoxide dismutase activity|positive regulation of Fe-SOD|activation of iron superoxide oxidoreductase|up regulation of Mn-SOD|up regulation of SOD-1|positive regulation of SOD-3|up-regulation of copper, zinc superoxide dismutase activity|activation of ferrisuperoxide dismutase activity|positive regulation of erythrocuprein|up-regulation of superoxide dismutase activity|positive regulation of hepatocuprein|positive regulation of SOD-2|positive regulation of Cu-Zn superoxide dismutase activity|activation of Mn, Fe superoxide dismutase|upregulation of superoxide dismutase I|up-regulation of hemocuprein|up regulation of manganese superoxide oxidoreductase|positive regulation of SOD-1|up regulation of Fe-SOD Any process that activates or increases the frequency, rate or extent of superoxide dismutase activity. GO:0045187 regulation of circadian sleep/wake cycle, sleep biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045187 regulation of sleep Any process that modulates the frequency, rate or extent of sleep; a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals. GO:1901672 positive regulation of systemic acquired resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901672 up regulation of systemic acquired resistance|upregulation of salicylic acid-dependent systemic resistance|upregulation of systemic acquired resistance|up-regulation of salicylic acid-dependent systemic resistance|activation of salicylic acid-dependent systemic resistance|up-regulation of systemic acquired resistance|activation of systemic acquired resistance|positive regulation of salicylic acid-dependent systemic resistance|up regulation of salicylic acid-dependent systemic resistance Any process that activates or increases the frequency, rate or extent of systemic acquired resistance. GO:0045188 regulation of circadian sleep/wake cycle, non-REM sleep biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045188 regulation of non-REM sleep Any process that modulates the frequency, rate or extent of non-rapid eye movement sleep. GO:1901680 sulfur-containing amino acid secondary active transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901680 Enables the transfer of sulfur-containing amino acid from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. GO:1901681 sulfur compound binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901681 sulfur molecular entity binding Interacting selectively and non-covalently with a sulfur compound. GO:0070129 regulation of mitochondrial translation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070129 regulation of mitochondrial protein anabolism|regulation of mitochondrial protein biosynthesis|regulation of mitochondrial protein synthesis|regulation of mitochondrial protein formation Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion. GO:0070127 tRNA aminoacylation for mitochondrial protein translation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070127 The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in ribosome-mediated polypeptide synthesis in a mitochondrion. GO:0070128 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0070128 GO:0070125 mitochondrial translational elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070125 mitochondrial translation elongation The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion. GO:0070126 mitochondrial translational termination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070126 mitochondrial translation termination The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa). GO:0070123 transforming growth factor beta receptor activity, type III biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070123 type III TGF-beta receptor activity|type III TGFbeta receptor activity|betaglycan|transforming growth factor beta ligand binding to type III receptor|type III transforming growth factor beta receptor activity|endoglin Combining with transforming growth factor beta to initiate a change in cell activity; facilitates ligand binding to type I and type II TGF-beta receptors. GO:0070124 mitochondrial translational initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070124 mitochondrial translation initiation The process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA. GO:0070121 Kupffer's vesicle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070121 KV development The progression of the Kupffer's vesicle over time from its initial formation until its mature state. The Kupffer's vesicle is a small but distinctive epithelial sac containing fluid, located midventrally posterior to the yolk cell or its extension, and transiently present during most of the segmentation period. GO:0070122 isopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070122 Catalysis of the hydrolysis of an isopeptide bond. An isopeptide bond is an amide linkage between a carboxyl group of one amino acid and an amino group of another amino acid in which at least one of these groups is not on the a-carbon of one of the amino acids (for example, the link between an epsilon-amino group of a lysine molecule to a carboxyl group on a second amino acid is an isopeptide bond). GO:0060908 plasmid copy number maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060908 The maintenance of the number of copies of extrachromosomal plasmid DNA. CHEBI:71596 mycocyclosin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71596 GO:0060909 regulation of DNA replication initiation involved in plasmid copy number maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060909 Any process that modulates the frequency, rate or extent of initiation of plasmid DNA replication that contributes to copy number maintenance. CHEBI:71598 3-oxo Delta(7)-steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71598 CHEBI:71599 pulcherriminic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71599 GO:0035944 perforin production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0035944 The appearance of a perforin protein due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0035945 mitochondrial ncRNA surveillance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035945 mitochondrial ncRNA quality control|mitochondrial aberrant ncRNA catabolic process|mitochondrial non-coding RNA surveillance The set of processes involved in identifying and degrading defective or aberrant non-coding RNA transcripts (ncRNAs) within the mitochondrion. GO:0035946 mitochondrial mRNA surveillance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035946 mitochondrial aberrant RNA catabolic process|mitochondrial mRNA quality control|mitochondrial messenger RNA surveillance The set of processes involved in identifying and degrading messenger RNA (mRNA) within the mitochondrion. GO:0035947 obsolete regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035947 regulation of glucose biosynthetic process by regulation of transcription from RNA polymerase II promoter|regulation of glucose biosynthesis by regulation of transcription from RNA polymerase II promoter|regulation of gluconeogenesis by regulation of transcription from Pol II promoter|regulation of glucose biosynthetic process by regulation of transcription from Pol II promoter|regulation of glucose biosynthesis by regulation of transcription from Pol II promoter OBSOLETE. Any process that modulates the frequency, rate or extent of gluconeogenesis, by regulation of transcription from an RNA polymerase II promoter. GO:0035948 obsolete positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035948 regulation of glucose biosynthetic process by up regulation of transcription from RNA polymerase II promoter|regulation of glucose biosynthesis by up regulation of transcription from RNA polymerase II promoter|regulation of gluconeogenesis by stimulation of transcription from RNA polymerase II promoter|regulation of glucose biosynthesis by positive regulation of transcription from RNA polymerase II promoter|regulation of gluconeogenesis by activation of transcription from RNA polymerase II promoter|regulation of gluconeogenesis by up-regulation of transcription from RNA polymerase II promoter|regulation of glucose biosynthesis by positive regulation of transcription from Pol II promoter|regulation of glucose biosynthetic process by positive regulation of transcription from Pol II promoter|regulation of glucose biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|regulation of glucose biosynthesis by upregulation of transcription from RNA polymerase II promoter|regulation of glucose biosynthetic process by upregulation of transcription from RNA polymerase II promoter|regulation of gluconeogenesis by positive regulation of transcription from Pol II promoter|regulation of glucose biosynthesis by up-regulation of transcription from RNA polymerase II promoter|regulation of glucose biosynthetic process by up-regulation of transcription from RNA polymerase II promoter|regulation of gluconeogenesis by upregulation of transcription from RNA polymerase II promoter|regulation of gluconeogenesis by up regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that activates or increases the frequency, rate or extent of gluconeogenesis by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:0035949 obsolete positive regulation of gluconeogenesis by negative regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035949 positive regulation of glucose biosynthetic process by negative regulation of transcription from RNA polymerase II promoter|positive regulation of glucose biosynthesis by down-regulation of transcription from RNA polymerase II promoter|positive regulation of glucose biosynthetic process by down-regulation of transcription from RNA polymerase II promoter|positive regulation of gluconeogenesis by inhibition of transcription from RNA polymerase II promoter|positive regulation of gluconeogenesis by negative regulation of transcription from Pol II promoter|positive regulation of glucose biosynthesis by negative regulation of transcription from RNA polymerase II promoter|positive regulation of gluconeogenesis by down-regulation of transcription from RNA polymerase II promoter|positive regulation of glucose biosynthesis by negative regulation of transcription from Pol II promoter|positive regulation of glucose biosynthetic process by negative regulation of transcription from Pol II promoter|positive regulation of glucose biosynthesis by down regulation of transcription from RNA polymerase II promoter|positive regulation of gluconeogenesis by downregulation of transcription from RNA polymerase II promoter|positive regulation of glucose biosynthetic process by down regulation of transcription from RNA polymerase II promoter|positive regulation of glucose biosynthetic process by downregulation of transcription from RNA polymerase II promoter|positive regulation of glucose biosynthesis by downregulation of transcription from RNA polymerase II promoter|positive regulation of gluconeogenesis by down regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that activates or increases the frequency, rate or extent of gluconeogenesis by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:0035940 negative regulation of peptidase activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035940 downregulation of peptidase activity in other organism|negative regulation of protease activity in other organism|down-regulation of protease activity in other organism|down regulation of peptidase activity in other organism|inhibition of protease activity in other organism Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of peptidase activity, the catalysis of the hydrolysis of peptide bonds in a protein, in a second organism. GO:0035941 androstenedione secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035941 androst-4-ene-3,17-dione secretion The regulated release of androstenedione (androst-4-ene-3,17-dione) into the circulatory system. GO:0035942 dehydroepiandrosterone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035942 DHEA secretion|dehydroisoandrosterone secretion|3beta-hydroxyandrost-5-en-17-one secretion The regulated release of dehydroepiandrosterone (3beta-hydroxyandrost-5-en-17-one) into the circulatory system. GO:0060910 negative regulation of DNA replication initiation involved in plasmid copy number maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060910 Any process that decreases the frequency, rate or extent of initiation of plasmid DNA replication that contributes to copy number maintenance. GO:0035943 estrone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035943 folliculin secretion|3-hydroxy-1,3,5(10)-estratrien-17-one secretion The regulated release of estrone into the circulatory system. GO:0060911 cardiac cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060911 cardiocyte cell fate commitment The commitment of cells to specific cardiac cell fates and their capacity to differentiate into cardiac cells. Cardiac cells are cells that comprise the organ which pumps blood through the circulatory system. GO:0060912 cardiac cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060912 cardiocyte cell fate specification The process involved in the specification of cardiac cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. GO:0060913 cardiac cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060913 cardiocyte cell fate determination The process involved in cardiac cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment. CHEBI:71590 (3E,5Z)-tetradecadienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71590 GO:0060914 heart formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060914 cardiogenesis The developmental process pertaining to the initial formation of the heart from unspecified parts. This process begins with the specific processes that contribute to the appearance of the heart field and the arrival of cardiac neural crest to the heart region. The process ends when the structural rudiment is recognizable. CHEBI:71591 2,3-bis-O-(geranylgeranyl)-sn-glycero-3-phospho-L-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71591 GO:0060915 mesenchymal cell differentiation involved in lung development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060915 The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the lung. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types. CHEBI:71592 anthocyanidin 3-O-[2-O-(4-coumaroyl)-alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71592 GO:0060916 mesenchymal cell proliferation involved in lung development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060916 The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population that contributes to the progression of the lung over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. GO:0060917 regulation of (1->6)-beta-D-glucan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060917 regulation of 1,6-beta-glucan biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->6)-beta-D-glucans. GO:0060918 auxin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060918 The directed movement of auxin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0035933 glucocorticoid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035933 The regulated release of any glucocorticoid hormone into the circulatory system. Glucocorticoids are a class of steroid hormones that regulate a variety of physiological processes, in particular control of the concentration of glucose in blood. GO:0035934 corticosterone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035934 The regulated release of corticosterone into the circulatory system. Corticosterone is a 21-carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands. GO:0035935 androgen secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035935 The regulated release of an androgen into the circulatory system. Androgens are steroid hormones that stimulate or control the development and maintenance of masculine characteristics in vertebrates. GO:0035936 testosterone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035936 The regulated release of testosterone into the circulatory system. Testosterone is an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5. GO:0035937 estrogen secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035937 oestrogen secretion The regulated release of estrogen into the circulatory system. Estrogen is a steroid hormone that stimulates or controls the development and maintenance of female sex characteristics in mammals. GO:0035938 estradiol secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035938 oestradiol secretion The regulated release of estradiol into the circulatory system. GO:0035939 microsatellite binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035939 variable number tandem repeat binding|microsatellite DNA binding|VNTR binding Interacting selectively and non-covalently with a microsatellite, a repeat_region in DNA containing repeat units (2 to 4 base pairs) that is repeated multiple times in tandem. GO:0035930 corticosteroid hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035930 corticosteroid secretion The regulated release of any corticosteroid hormone into the circulatory system. GO:0035931 mineralocorticoid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035931 The regulated release of any mineralocorticoid into the circulatory system. Mineralocorticoids are a class of steroid hormones that regulate water and electrolyte metabolism. GO:0035932 aldosterone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035932 The regulated release of aldosterone into the circulatory system. Aldosterone is a pregnane-based steroid hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney. GO:0060900 embryonic camera-type eye formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060900 The developmental process pertaining to the initial formation of a camera-type eye from unspecified neurectoderm. This process begins with the differentiation of cells that form the optic field and ends when the optic cup has attained its shape. GO:0060901 regulation of hair cycle by canonical Wnt signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060901 regulation of hair cycle by Wnt receptor signaling pathway through beta-catenin|regulation of hair cycle by canonical Wnt receptor signalling pathway|regulation of hair cycle by canonical Wnt receptor signaling pathway|regulation of hair cycle by canonical Wnt-activated signaling pathway The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that modulates the rate, frequency or extent of the hair cycle. GO:0060902 regulation of hair cycle by BMP signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060902 regulation of hair cycle by BMP signalling pathway A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that modulates the rate, frequency or extent of the hair cycle. GO:0060903 positive regulation of meiosis I biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060903 Any process that increases the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells. GO:0060904 regulation of protein folding in endoplasmic reticulum biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060904 Any process that modulates the rate, frequency or extent of the protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation). GO:0060905 regulation of induction of conjugation upon nitrogen starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060905 Any process that modulates the frequency of induction of conjugation upon nitrogen starvation, the process in which a cell initiates conjugation with cellular fusion upon nitrogen starvation. GO:0060906 negative regulation of heterochromatin assembly by small RNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060906 negative regulation of chromatin silencing by small RNA|negative regulation of RNAi-mediated heterochromatin assembly Any process that decreases the frequency, rate or extent of heterochromatin assembly by small RNA. GO:0060907 positive regulation of macrophage cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060907 Any process that increases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0035922 foramen ovale closure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035922 foramen ovale of heart closure The morphogenetic process in which the foramen ovale closes after birth, to prevent blood flow between the right and left atria. In the fetal heart, the foramen ovale allows blood to enter the left atrium from the right atrium. Closure of the foramen ovale after birth stops this blood flow. GO:0035923 flurbiprofen binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035923 2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid binding Interacting selectively and non-covalently with flurbiprofen. GO:0035924 cellular response to vascular endothelial growth factor stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035924 cellular response to VEGFB|cellular response to VEGFA|cellular response to vascular endothelial growth factor|cellular response to VEGF Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vascular endothelial growth factor stimulus. GO:0035925 mRNA 3'-UTR AU-rich region binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035925 mRNA 3'-UTR adenylate/uridylate-rich element binding|adenylate/uridylate-rich element binding|ARE binding|AU-rich element binding Interacting selectively and non-covalently with a region containing frequent adenine and uridine bases within the 3' untranslated region of a mRNA molecule or in pre-mRNA intron. The ARE-binding element consensus is UUAUUUAUU. ARE-binding proteins control the stability and/or translation of mRNAs. GO:0035926 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035926 GO:0035927 RNA import into mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035927 nuclear-encoded RNA import into mitochondrion|cytoplasmic RNA import into mitochondrion The process in which a rRNA, ribosomal ribonucleic acid, is transported from the cytosol, into the mitochondrial matrix. GO:0035928 rRNA import into mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035928 nuclear-encoded rRNA import into mitochondrion|cytoplasmic rRNA import into mitochondrion The process in which a rRNA, ribosomal ribonucleic acid, transported from the cytosol, into the mitochondrial matrix. GO:0035929 steroid hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035929 The regulated release of any steroid that acts as a hormone into the circulatory system. GO:0060930 sinoatrial node cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060930 SA node cell commitment|sinus node cell commitment|SAN cell commitment The commitment of cells to sinoatrial (SA) node cell fates and their capacity to differentiate into SA node cells. SA node cells are pacemaker cells that are found in the sinoatrial node. GO:0060931 sinoatrial node cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060931 SA node cell development|SAN cell development|sinus node cell development The process whose specific outcome is the progression of a sinoatrial (SA) node cell over time, from its formation to the mature state. SA node cells are pacemaker cells that are found in the sinoatrial node. GO:0035920 negative regulation of high voltage-gated calcium channel activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035920 negative regulation of high voltage-dependent calcium channel activity in other organism|inhibition of high voltage-gated calcium channel activity in other organism|negative regulation of high voltage gated calcium channel activity in other organism|downregulation of high voltage-gated calcium channel activity in other organism|down-regulation of high voltage-gated calcium channel activity in other organism Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a high voltage-gated calcium channel in another organism. A high voltage-gated channel is a channel whose open state is dependent on high voltage across the membrane in which it is embedded. GO:0035921 desmosome disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035921 desmosome dissociation The controlled breakdown of a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm. GO:0060932 His-Purkinje system cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060932 The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the His-Purkinje system. These cells form the fibers regulate cardiac muscle contraction in the ventricles. GO:0060933 His-Purkinje system cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060933 The process whose specific outcome is the progression of a His-Purkinje cell over time, from its formation to the mature state. These cells form the fibers that regulate cardiac muscle contraction in the ventricles. GO:0060934 His-Purkinje system cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060934 The commitment of cells to His-Purkinje cell fates and their capacity to differentiate into His-Purkinje cells. These cells form the fibers that regulate cardiac muscle contraction in the ventricles. GO:0060935 cardiac fibroblast cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060935 The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules. GO:0060936 cardiac fibroblast cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060936 The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules. GO:0060937 cardiac fibroblast cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060937 The commitment of cells to a cardiac fibroblast fate and their capacity to differentiate into cardiac fibroblast cells. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules. GO:0060938 epicardium-derived cardiac fibroblast cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060938 The process in which an epicardial cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules. GO:0060939 epicardium-derived cardiac fibroblast cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060939 The process whose specific outcome is the progression of an epicardial-derived cardiac fibroblast over time, from its formation to the mature state. A epicardial-derived cardiac fibroblast is a connective tissue cell of the heart that arises from the epicardium and secretes an extracellular matrix rich in collagen and other macromolecules. GO:0035919 negative regulation of low voltage-gated calcium channel activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035919 down-regulation of low voltage-gated calcium channel activity in other organism|negative regulation of low voltage-dependent calcium channel activity in other organism|downregulation of low voltage-gated calcium channel activity in other organism|negative regulation of low voltage gated calcium channel activity in other organism|inhibition of low voltage-gated calcium channel activity in other organism Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a low voltage-gated calcium channel in another organism. A low voltage-gated channel is a channel whose open state is dependent on low voltage across the membrane in which it is embedded. GO:0060919 auxin influx biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060919 The process involved in the transport of auxin into the cell. GO:0045303 diaminobutyrate-2-oxoglutarate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045303 RHEA:11160|KEGG_REACTION:R06977|MetaCyc:R101-RXN|EC:2.6.1.76 diaminobutyrate--2-oxoglutarate aminotransferase activity|diaminobutyrate transaminase activity|DABA aminotransferase activity|diaminibutyric acid aminotransferase activity|L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase activity|L-2,4-diaminobutyrate:2-oxoglutarate 4-aminotransferase activity|EctB|L-2,4-diaminobutanoate:2-oxoglutarate 4-aminotransferase activity|2,4-diaminobutyrate 4-aminotransferase activity|DAB aminotransferase activity Catalysis of the reaction: 2-oxoglutarate + L-2,4-diaminobutyrate = L-aspartate 4-semialdehyde + L-glutamate. GO:0035911 descending aorta morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035911 The process in which the anatomical structures of the descending aorta are generated and organized. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once. GO:0045304 regulation of establishment of competence for transformation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045304 regulator of establishment of competence for transformation activity Any process that modulates the frequency, rate or extent of the process in which a cell becomes able to take up and incorporate extracellular DNA into its genome. CHEBI:141610 3-hydroxy-D-kynurenine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_141610 GO:0035912 dorsal aorta morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035912 The process in which the anatomical structures of the dorsal aorta are generated and organized. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once. GO:0045301 tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine)-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045301 2-methylthio-cis-ribozeatin hydroxylase activity|tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyladenosine)-hydroxylase activity|tRNA-(ms2io6A)-hydroxylase activity Catalysis of the reaction: tRNA-(2-methylthio-N-6-isopentenyl adenosine) = tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine) + O2. 2-methylthio-N-6-isopentenyl adenosine is also known as ms2i6A; 2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine is also known as ms2io6A and 2-methylthio-cis-ribozeatin. GO:0035913 ventral aorta morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035913 The process in which the anatomical structures of the ventral aorta are generated and organized. The ventral aorta is a blood vessel in a single-pass circulatory system that carries de-oxygenated blood from the heart to the gills. In a single-pass circulatory system blood passes once through the heart to supply the body once. GO:0045302 choloylglycine hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045302 MetaCyc:CHOLOYLGLYCINE-HYDROLASE-RXN|RHEA:19353|EC:3.5.1.24 choloyltaurine hydrolase activity|bile salt hydrolase activity|glycocholase activity|3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oylglycine amidohydrolase activity Catalysis of the reaction: 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholan-24-oylglycine + H2O = 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholanate + glycine. GO:0035914 skeletal muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035914 The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle. GO:0035915 pore formation in membrane of other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035915 pore-forming toxin activity|pore formation in other organism|pore complex biogenesis in other organism|pore biosynthesis in other organism|pore complex assembly in other organism The aggregation, arrangement and bonding together of a set of components by an organism to form a pore complex in a membrane of another organism. GO:0035916 modulation of calcium channel activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035916 Any process in which an organism effects a change in the frequency, rate or extent of the activity of a calcium channel in another organism. GO:0045300 acyl-[acyl-carrier-protein] desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045300 MetaCyc:1.14.19.2-RXN|EC:1.14.19.2|MetaCyc:PWY-5147 acyl-acyl-carrier-protein desaturase activity|stearyl-ACP desaturase activity|stearyl acyl carrier protein desaturase activity|acyl-[acyl-carrier protein] desaturase activity|acyl-acyl-carrier-protein, hydrogen-donor:oxygen oxidoreductase activity Catalysis of the reaction: stearoyl-[acyl-carrier protein] + reduced acceptor + O2 = oleoyl-[acyl-carrier protein] + acceptor + H2O. The enzyme requires ferredoxin. GO:0035917 negative regulation of calcium channel activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035917 down-regulation of calcium channel activity in other organism|downregulation of calcium channel activity in other organism|inhibition of calcium channel activity in other organism Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a calcium channel in another organism. GO:0035918 negative regulation of voltage-gated calcium channel activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035918 negative regulation of voltage gated calcium channel activity in other organism|inhibition of voltage-gated calcium channel activity in other organism|negative regulation of voltage-sensitive calcium channel activity in other organism|down-regulation of voltage-gated calcium channel activity in other organism|negative regulation of voltage-dependent calcium channel activity in other organism|downregulation of voltage-gated calcium channel activity in other organism Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated calcium channel in another organism. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. CHEBI:141617 hapalindole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_141617 GO:0045309 protein phosphorylated amino acid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045309 phosphoprotein amino acid binding Interacting selectively and non-covalently with a phosphorylated amino acid residue within a protein. CHEBI:141616 hapalindole-type alkaloid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_141616 GO:0045307 obsolete activator of the establishment of competence for transformation activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045307 activator of the establishment of competence for transformation activity OBSOLETE. Activates the establishment of competence for transformation. GO:0045308 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045308 GO:0045305 obsolete regulator of establishment of competence for transformation activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045305 regulator of establishment of competence for transformation activity OBSOLETE. Functions to either promote or inhibit the establishment of competence for transformation. GO:0060920 cardiac pacemaker cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060920 pacemaker cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions. GO:0060921 sinoatrial node cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060921 sinus node cell differentiation|SA node cell differentiation|SAN cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a sinoatrial (SA) node cell. SA node cells are pacemaker cells that are found in the sinoatrial node. GO:0035910 ascending aorta morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035910 The process in which the anatomical structures of the ascending aorta are generated and organized. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once. GO:0045306 obsolete inhibitor of the establishment of competence for transformation activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045306 inhibitor of the establishment of competence for transformation activity OBSOLETE. Inhibits the establishment of competence for transformation. GO:0060922 atrioventricular node cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060922 AV node cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an atrioventricular (AV) node cell. AV node cells are pacemaker cells that are found in the atrioventricular node. GO:0060923 cardiac muscle cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060923 cardiomyocyte cell fate commitment|heart muscle cell fate commitment The commitment of cells to specific cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. GO:0060924 atrial cardiac muscle cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060924 atrial heart muscle cell fate commitment|atrial cardiomyocyte cell fate commitment The commitment of cells to atrial cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells of the atrium. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. GO:0060925 ventricular cardiac muscle cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060925 ventricular cardiomyocyte cell fate commitment|ventricular heart muscle cell fate commitment The commitment of cells to ventricular cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells of the ventricle. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. GO:0060926 cardiac pacemaker cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060926 pacemaker cell development The process whose specific outcome is the progression of a pacemaker cell over time, from its formation to the mature state. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions. GO:0060927 cardiac pacemaker cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060927 pacemaker cell fate commitment The commitment of cells to pacemaker cell fates and their capacity to differentiate into pacemaker cells. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions. CHEBI:141619 fischerindole alkaloid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_141619 GO:0060928 atrioventricular node cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060928 AV node cell development The process whose specific outcome is the progression of an atrioventricular (AV) node cell over time, from its formation to the mature state. GO:0060929 atrioventricular node cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060929 AV node cell fate commitment The commitment of cells to atrioventricular (AV) node cell fates and their capacity to differentiate into AV node cells. GO:0035908 ventral aorta development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035908 The progression of the ventral aorta over time, from its initial formation to the mature structure. The ventral aorta is a blood vessel in a single-pass circulatory system that carries de-oxygenated blood from the heart to the gills. In a single-pass circulatory system blood passes once through the heart to supply the body once. GO:0035909 aorta morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035909 The process in which the anatomical structures of an aorta are generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body. UBERON:0003528 brain gray matter biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003528 gray matter of brain|grey matter of brain|grey substance of brain|brain grey substance|brain grey matter A gray matter that is part of a brain [Automatically generated definition]. UBERON:0003529 respiratory system lymphatic vessel endothelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003529 apparatus respiratorius lymph vessel endothelium|apparatus respiratorius endothelium of lymph vessel|lymphatic vessel endothelium of respiratory system|lymphatic vessel endothelium of apparatus respiratorius|respiratory system lymph vessel endothelium|apparatus respiratorius lymphatic vessel endothelium|endothelium of lymph vessel of respiratory system|lymph vessel endothelium of apparatus respiratorius|lymph vessel endothelium of respiratory system|respiratory system endothelium of lymph vessel|respiratory system lymphatic vessel endothelium|endothelium of lymph vessel of apparatus respiratorius An lymphatic vessel endothelium that is part of a respiratory system [Automatically generated definition]. UBERON:0003526 respiratory system capillary biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003526 capillary vessel of respiratory system|respiratory system blood capillary|capillary vessel of apparatus respiratorius|apparatus respiratorius capillary|apparatus respiratorius capillary vessel|blood capillary of apparatus respiratorius|apparatus respiratorius blood capillary|capillary of apparatus respiratorius|respiratory system capillary vessel|capillary of respiratory system|blood capillary of respiratory system A capillary that is part of a respiratory system [Automatically generated definition]. UBERON:0003527 kidney capillary biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003527 renal capillary|capillary of kidney|blood capillary of kidney|capillary vessel of kidney|kidney capillary vessel|kidney blood capillary A capillary that is part of a kidney [Automatically generated definition]. GO:0045314 regulation of compound eye photoreceptor development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045314 regulation of eye photoreceptor development Any process that modulates the frequency, rate or extent of compound eye photoreceptor development. GO:0035900 response to isolation stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035900 response to social isolation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lack of contact with other members of the same species. GO:0045315 positive regulation of compound eye photoreceptor development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045315 up regulation of eye photoreceptor development|positive regulation of eye photoreceptor development|activation of eye photoreceptor development|stimulation of eye photoreceptor development|up-regulation of eye photoreceptor development|upregulation of eye photoreceptor development Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor development. GO:0035901 cellular response to isolation stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035901 cellular response to social isolation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lack of contact with other members of the same species. GO:0045312 nor-spermidine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045312 nor-spermidine anabolism|nor-spermidine synthesis|nor-spermidine formation|nor-spermidine biosynthesis The chemical reactions and pathways resulting in the formation of nor-spermidine, a compound related to spermidine, N-(3-aminopropyl)-1,4-diaminobutane. GO:0035902 response to immobilization stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035902 response to restraint stress|response to immobilisation stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of being rendered immobile. GO:0045313 rhabdomere membrane biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045313 A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a rhabdomere membrane. GO:0035903 cellular response to immobilization stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035903 cellular response to immobilisation stress|cellular response to restraint stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of being rendered immobile. GO:0035904 aorta development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035904 The progression of the aorta over time, from its initial formation to the mature structure. An aorta is an artery that carries blood from the heart to other parts of the body. GO:0045310 obsolete phosphoserine/phosphothreonine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045310 phosphoserine/phosphothreonine binding OBSOLETE. Interacting selectively with a phosphorylated serine or threonine residue within a protein. GO:0045311 invasive growth in response to pheromone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045311 The growth of colonies in filamentous chains of cells as a result of a pheromone stimulus. GO:0035905 ascending aorta development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035905 The progression of the ascending aorta over time, from its initial formation to the mature structure. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once. GO:0035906 descending aorta development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035906 The progression of the descending aorta over time, from its initial formation to the mature structure. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once. GO:0035907 dorsal aorta development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035907 The progression of the dorsal aorta over time, from its initial formation to the mature structure. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once. GO:0060950 cardiac glial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060950 The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the heart. GO:0060951 neural crest-derived cardiac glial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060951 The process in which a neural crest cell acquires the specialized features of a glial cell of the heart. GO:0045318 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045318 GO:0060952 cardiac glial cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060952 The process aimed at the progression of a cardiac glial cell over time, from its formation to the fully functional mature cell. GO:0045319 obsolete SRP-independent cotranslational protein-membrane targeting, translocation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045319 SRP-independent cotranslational membrane targeting, translocation|SRP-independent cotranslational protein-membrane targeting, translocation OBSOLETE. The process during cotranslational membrane targeting wherein proteins move across a membrane. This process is independent of SRP and signal recognition. GO:0060953 cardiac glial cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060953 The commitment of cells to cardiac glial cell fates and their capacity to differentiate into cardiac glial cells. GO:0045316 negative regulation of compound eye photoreceptor development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045316 negative regulation of eye photoreceptor development|down-regulation of eye photoreceptor development|inhibition of eye photoreceptor development|down regulation of eye photoreceptor development|downregulation of eye photoreceptor development Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor development. GO:0060954 neural crest-derived cardiac glial cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060954 The process aimed at the progression of a neural crest-derived cardiac glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. GO:0045317 equator specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045317 The formation and development of the equator that forms the boundary between the photoreceptors in the dorsal sector of the eye and those in the ventral sector, dividing the eye into dorsal and ventral halves. GO:0060955 neural crest-derived cardiac glial cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060955 The commitment of neural crest cells to cardiac glial cell fates and their capacity to differentiate into cardiac glial cells. UBERON:0003535 vagus X nerve trunk biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003535 vagal X nerve trunk|vagus neural trunk|vagus nerve trunk|trunk of vagal nerve|trunk of vagus nerve|vagal nerve trunk A nerve trunk that is part of a vagus nerve. GO:0060956 endocardial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060956 The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. The endocardium is the innermost layer of tissue of the heart, and lines the heart chambers. UBERON:0003533 manual digit skin biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003533 skin of hand digit|hand digit skin|skin of digit of hand|skin of digitus manus|skin of digit of terminal segment of free upper limb|digitus manus skin|fore limb digit skin|digit of hand skin|finger skin|skin of terminal segment of free upper limb digit|skin of finger|digit of terminal segment of free upper limb skin|hand digit skin|terminal segment of free upper limb digit skin A zone of skin that is part of a finger [Automatically generated definition]. GO:0060957 endocardial cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060957 The commitment of a cell to an endocardial cell fate and its capacity to differentiate into an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. GO:0060958 endocardial cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060958 The progression of an endocardial cell over time, from its formation to the mature cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. UBERON:0003534 tail skin biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003534 skin of post-vent region|skin of tail|post-vent region skin A zone of skin that is part of a tail [Automatically generated definition]. GO:0060959 cardiac neuron development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060959 heart neuron development The process whose specific outcome is the progression of a cardiac neuron over time, from its formation to the mature state. UBERON:0003531 forelimb skin biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003531 wing skin|skin of upper limb|skin of forelimb|skin of fore limb|upper limb skin|fore limb skin|anteriormost limb skin A zone of skin that is part of a forelimb [Automatically generated definition]. UBERON:0003532 hindlimb skin biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003532 hind limb skin|skin of lower limb|skin of hind limb|skin of lower extremity|skin of hindlimb|lower limb skin A zone of skin that is part of a hindlimb [Automatically generated definition]. UBERON:0003530 pedal digit skin biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003530 foot digit skin|skin of foot digit|skin of digitus pedis|skin of digit of foot|skin of digit of terminal segment of free lower limb|digit of foot skin|digitus pedis skin|hind limb digit skin|skin of terminal segment of free lower limb digit|toe skin|foot digit skin|digit of terminal segment of free lower limb skin|skin of toe|terminal segment of free lower limb digit skin A zone of skin that is part of a toe [Automatically generated definition]. UBERON:0003519 thoracic cavity blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003519 chest cavity blood vessel|blood vessel of thoracic cavity|blood vessel of cavity of chest|blood vessel of pectoral cavity|pectoral cavity blood vessel|cavity of chest blood vessel|blood vessel of chest cavity|blood vessel of cavity of thorax|cavity of thorax blood vessel A blood vessel that is part of a thoracic cavity [Automatically generated definition]. UBERON:0003517 kidney blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003517 blood vessel of kidney|renal blood vessel A blood vessel that is part of a kidney [Automatically generated definition]. UBERON:0003515 forelimb blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003515 fore limb blood vessel|anteriormost limb blood vessel|wing blood vessel|blood vessel of forelimb|blood vessel of anteriormost limb|blood vessel of upper extremity|blood vessel of fore limb A blood vessel that is part of a forelimb [Automatically generated definition]. UBERON:0003516 hindlimb blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003516 hind limb blood vessel|blood vessel of hind limb|blood vessel of lower extremity|blood vessel of hindlimb A blood vessel that is part of a hindlimb [Automatically generated definition]. GO:0045325 peptidyl-tryptophan hydroxylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045325 RESID:AA0322 The hydroxylation of peptidyl-tryptophan, to form peptidyl-L-3-hydroxytryptophan. GO:0045326 protein-DNA covalent cross-linking via the 3'-end to peptidyl-tyrosine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045326 RESID:AA0323 DNA-protein covalent cross-linking via the 3'-end to peptidyl-tyrosine The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-3'-DNA)-L-tyrosine. GO:0045323 interleukin-1 receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045323 IL-1 receptor complex A protein complex that binds interleukin-1; comprises an alpha and a beta subunit. GO:0045324 late endosome to vacuole transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045324 The directed movement of substances from late endosomes to the vacuole. In yeast, after transport to the prevacuolar compartment, endocytic content is delivered to the late endosome and on to the vacuole. This pathway is analogous to endosome to lysosome transport. GO:0045321 leukocyte activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045321 Wikipedia:Immunologic_activation immune cell activation|leucocyte activation A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor. GO:0045322 unmethylated CpG binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045322 Interacting selectively and non-covalently with unmethylated CpG motifs. Unmethylated CpG dinucleotides are often associated with gene promoters. GO:0045320 chloroplast proton-transporting ATP synthase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045320 hydrogen-translocating F-type ATPase complex|chloroplast hydrogen-translocating F-type ATPase complex|chloroplast proton-transporting F-type ATPase complex A proton-transporting ATP synthase complex found in the chloroplast thylakoid membrane; it catalyzes the phosphorylation of ADP to ATP during photo-phosphorylation. GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060940 A transition where an epicardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will mature into a cardiac fibroblast. GO:0045329 carnitine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045329 carnitine anabolism|carnitine biosynthesis|carnitine synthesis|vitamin Bt biosynthetic process|carnitine formation|vitamin Bt biosynthesis The chemical reactions and pathways resulting in the formation of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane. GO:0060941 epicardium-derived cardiac fibroblast cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060941 The commitment of an epicardial cell to a cardiac fibroblast cell fate and its capacity to differentiate into a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules. GO:0060942 neural crest-derived cardiac fibroblast cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060942 The process in which a neural crest cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules. GO:0045327 protein-DNA covalent cross-linking via peptidyl-tyrosine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045327 DNA-protein covalent cross-linking via peptidyl-tyrosine The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue. GO:0060943 neural crest-derived cardiac fibroblast cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060943 The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation from a neural crest cell to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules. GO:0045328 cytochrome P450 4A1-heme linkage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045328 RESID:AA0324 cytochrome P450 4A1-haem linkage The covalent linkage of heme to cytochrome P450 4A1 via hydroxyheme-L-glutamyl ester. UBERON:0003524 tail blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003524 blood vessel of tail|post-vent region blood vessel|blood vessel of post-vent region A blood vessel that is part of a tail [Automatically generated definition]. GO:0060944 neural crest-derived cardiac fibroblast cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060944 The commitment of neural crest cells to a cardiac fibroblast fate and their capacity to differentiate into cardiac fibroblast cells. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules. GO:0060945 cardiac neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060945 heart neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron of the heart. UBERON:0003522 manual digit blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003522 blood vessel of terminal segment of free upper limb digit|finger blood vessel|digit of terminal segment of free upper limb blood vessel|hand digit blood vessel|terminal segment of free upper limb digit blood vessel|hand digit blood vessel|blood vessel of digit of terminal segment of free upper limb A blood vessel that is part of a finger [Automatically generated definition]. GO:0060946 cardiac blood vessel endothelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060946 The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell of the heart. Blood vessel endothelial cells are thin flattened cells that line the inside surfaces of blood vessels. UBERON:0003523 manus blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003523 blood vessel of hand|blood vessel of manus|hand blood vessel A blood vessel that is part of a manus [Automatically generated definition]. GO:0060947 cardiac vascular smooth muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060947 heart vascular smooth muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers. UBERON:0003520 pelvis blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003520 blood vessel of pelvis A blood vessel that is part of a pelvis [Automatically generated definition]. GO:0060948 cardiac vascular smooth muscle cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060948 heart vascular smooth muscle cell development The process whose specific outcome is the progression of a cardiac vascular smooth muscle cell over time, from its formation to the mature state. UBERON:0003521 pes blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003521 blood vessel of foot|foot blood vessel A blood vessel that is part of a foot [Automatically generated definition]. GO:0060949 cardiac vascular smooth muscle cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060949 heart vascular smooth muscle cell fate commitment The commitment of cells to a cardiac vascular smooth muscle cell fate and its capacity to differentiate into a cardiac vascular smooth muscle cell. CHEBI:46574 wybutosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46574 UBERON:0003508 pedal digit blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003508 digitus pedis blood vessel|digit of foot blood vessel|blood vessel of terminal segment of free lower limb digit|hind limb digit blood vessel|toe blood vessel|foot digit blood vessel|digit of terminal segment of free lower limb blood vessel|blood vessel of toe|terminal segment of free lower limb digit blood vessel|foot digit blood vessel|blood vessel of foot digit|blood vessel of digit of foot|blood vessel of digitus pedis|blood vessel of digit of terminal segment of free lower limb A blood vessel that is part of a toe [Automatically generated definition]. UBERON:0003509 arterial blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003509 A blood vessel that is part of the arterial system. Includes artery, arteriole and aorta. UBERON:0003506 chest blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003506 blood vessel of anterolateral part of thorax|anterolateral part of thorax blood vessel|anterior thoracic region blood vessel|blood vessel of anterior thoracic region|blood vessel of chest|front of thorax blood vessel|blood vessel of front of thorax A blood vessel that is part of a chest [Automatically generated definition]. UBERON:0003507 arm blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003507 blood vessel of arm A blood vessel that is part of an arm [Automatically generated definition]. UBERON:0003504 respiratory system blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003504 blood vessel of apparatus respiratorius|blood vessel of respiratory system|apparatus respiratorius blood vessel A blood vessel that is part of a respiratory system [Automatically generated definition]. UBERON:0003505 trachea blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003505 blood vessel of trachea A blood vessel that is part of a trachea. GO:0045336 clathrin-coated phagocytic vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045336 clathrin-coated phagosome A clathrin-coated, membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis. GO:0045337 farnesyl diphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045337 MetaCyc:PWY-5123 farnesyl diphosphate anabolism|farnesyl diphosphate synthesis|farnesyl diphosphate formation|farnesyl diphosphate biosynthesis The chemical reactions and pathways resulting in the formation of farnesyl diphosphate. GO:0045334 clathrin-coated endocytic vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045334 NIF_Subcellular:sao1243595998 A clathrin-coated, membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance. GO:0045335 phagocytic vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045335 Wikipedia:Phagosome phagosome A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis. GO:0045332 phospholipid translocation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045332 phospholipid scrambling|flippase The movement of a phospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet. CHEBI:46570 cis-zeatin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46570 GO:0045333 cellular respiration biolink:BiologicalProcess go-plus goslim_yeast|goslim_candida|goslim_pir|goslim_aspergillus http://purl.obolibrary.org/obo/GO_0045333 Wikipedia:Cellular_respiration respiration|oxidative metabolism|oxidative metabolic process The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which either requires oxygen (aerobic respiration) or does not (anaerobic respiration). GO:0045330 aspartyl esterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045330 Catalysis of the hydrolysis of an ester bond by a mechanism involving a catalytically active aspartic acid residue. GO:0045331 obsolete coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045331 heterodisulfide reductase activity|coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase activity|coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulphide hydrogenase activity OBSOLETE. Catalysis of the reaction: coenzyme-M 7-mercaptoheptanoylthreonine-phosphate heterodisulfide + H2 = coenzyme-M + N-(7-mercaptoheptanoyl)threonine O3-phosphate. GO:0060970 embryonic heart tube dorsal/ventral pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060970 The regionalization process in which the areas along the dorsal/ventral axis of the embryonic heart tube are established. This process will determine the patterns of cell differentiation along the axis. GO:0060971 embryonic heart tube left/right pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060971 The pattern specification process that results in the subdivision of the left/right axis of the embryonic heart tube in space to define an area or volume in which specific patterns of cell differentiation will take place. GO:0060972 left/right pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060972 The pattern specification process that results in the subdivision of the left/right axis in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment. GO:0060973 cell migration involved in heart development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060973 The orderly movement of a cell from one site to another that will contribute to the progression of the heart over time, from its initial formation, to the mature organ. GO:0060974 cell migration involved in heart formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060974 The orderly movement of a cell from one site to another that contribute to the formation of the heart. The initial heart structure is made up of mesoderm-derived heart progenitor cells and neural crest-derived cells. GO:0060975 cardioblast migration to the midline involved in heart field formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060975 cardiac progenitor cell midline migration|cardioblast midline convergence The orderly movement of a cardioblast toward the midline to form the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. GO:0045338 farnesyl diphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045338 farnesyl diphosphate metabolism The chemical reactions and pathways involving farnesyl diphosphate, an intermediate in carotenoid, sesquiterpene, squalene and sterol biosynthesis, as well as a substrate in protein farnesylation. GO:0060976 coronary vasculature development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060976 heart vasculature development|cardiac blood vessel development|cardiac vasculature development|coronary blood vessel development|heart blood vessel development The process whose specific outcome is the progression of the blood vessels of the heart over time, from its formation to the mature structure. GO:0045339 farnesyl diphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045339 farnesyl diphosphate breakdown|farnesyl diphosphate catabolism|farnesyl diphosphate degradation The chemical reactions and pathways resulting in the breakdown of farnesyl diphosphate. UBERON:0003513 trunk blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003513 blood vessel of trunk|blood vessel of torso|torso blood vessel A blood vessel that is part of a trunk [Automatically generated definition]. GO:0060977 coronary vasculature morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060977 cardiac blood vessel morphogenesis|cardiac vasculature morphogenesis|coronary blood vessel morphogenesis|heart blood vessel morphogenesis|heart vasculature morphogenesis The process in which the anatomical structures of blood vessels of the heart are generated and organized. The blood vessel is the vasculature carrying blood. GO:0060978 angiogenesis involved in coronary vascular morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060978 angiogenesis involved in cardiac vascular morphogenesis|coronary vasculature angiogenesis|angiogenesis involved in heart vascular morphogenesis|coronary blood vessel angiogenesis Blood vessel formation in the heart when new vessels emerge from the proliferation of pre-existing blood vessels. UBERON:0003514 limb blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003514 blood vessel of limb A blood vessel that is part of a limb [Automatically generated definition]. UBERON:0003511 iris blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003511 blood vessel of iris A blood vessel that is part of a iris [Automatically generated definition]. GO:0060979 vasculogenesis involved in coronary vascular morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060979 vasculogenesis involved in coronary blood vessel morphogenesis|coronary vasculogenesis The differentiation of endothelial cells from progenitor cells that contributes to blood vessel development in the heart, and the de novo formation of blood vessels and tubes. UBERON:0003512 lung blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003512 pulmonary vascular element|blood vessel of lung A blood vessel that is part of a lung [Automatically generated definition]. UBERON:0003510 eyelid blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003510 blood vessel of blepharon|blood vessel of eyelid|blepharon blood vessel A blood vessel that is part of a eyelid [Automatically generated definition]. GO:0045340 mercury ion binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045340 mercury binding Interacting selectively and non-covalently with mercury (Hg) ions. GO:0045347 negative regulation of MHC class II biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045347 negative regulation of major histocompatibility complex class II biosynthetic process|negative regulation of major histocompatibility complex class II biosynthesis|down regulation of MHC class II biosynthetic process|downregulation of MHC class II biosynthetic process|negative regulation of MHC class II anabolism|negative regulation of MHC class II synthesis|negative regulation of MHC class II formation|negative regulation of MHC class II biosynthesis|down-regulation of MHC class II biosynthetic process|inhibition of MHC class II biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II. GO:0045348 positive regulation of MHC class II biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045348 upregulation of MHC class II biosynthetic process|positive regulation of major histocompatibility complex class II biosynthesis|positive regulation of major histocompatibility complex class II biosynthetic process|up regulation of MHC class II biosynthetic process|activation of MHC class II biosynthetic process|positive regulation of MHC class II anabolism|positive regulation of MHC class II biosynthesis|stimulation of MHC class II biosynthetic process|positive regulation of MHC class II synthesis|positive regulation of MHC class II formation|up-regulation of MHC class II biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II. GO:0045345 positive regulation of MHC class I biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045345 positive regulation of MHC class I synthesis|positive regulation of MHC class I formation|positive regulation of MHC class I biosynthesis|up regulation of MHC class I biosynthetic process|positive regulation of major histocompatibility complex class I biosynthetic process|positive regulation of major histocompatibility complex class I biosynthesis|upregulation of MHC class I biosynthetic process|stimulation of MHC class I biosynthetic process|activation of MHC class I biosynthetic process|up-regulation of MHC class I biosynthetic process|positive regulation of MHC class I anabolism Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I. GO:0045346 regulation of MHC class II biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045346 regulation of MHC class II biosynthesis|regulation of major histocompatibility complex class II biosynthetic process|regulation of major histocompatibility complex class II biosynthesis|regulation of MHC class II anabolism|regulation of MHC class II synthesis|regulation of MHC class II formation Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II. GO:0045343 regulation of MHC class I biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045343 regulation of major histocompatibility complex class I biosynthetic process|regulation of major histocompatibility complex class I biosynthesis|regulation of MHC class I biosynthesis|regulation of MHC class I anabolism|regulation of MHC class I synthesis|regulation of MHC class I formation Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I. GO:0045344 negative regulation of MHC class I biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045344 down-regulation of MHC class I biosynthetic process|negative regulation of MHC class I biosynthesis|negative regulation of MHC class I synthesis|negative regulation of MHC class I formation|downregulation of MHC class I biosynthetic process|down regulation of MHC class I biosynthetic process|negative regulation of major histocompatibility complex class I biosynthesis|negative regulation of major histocompatibility complex class I biosynthetic process|inhibition of MHC class I biosynthetic process|negative regulation of MHC class I anabolism Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I. GO:0045341 MHC class I biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045341 MHC class I anabolism|MHC class I synthesis|MHC class I formation|major histocompatibility complex class I biosynthesis|major histocompatibility complex class I biosynthetic process|MHC class I biosynthesis The chemical reactions and pathways resulting in the formation of major histocompatibility protein class I. GO:0045342 MHC class II biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045342 major histocompatibility complex class II biosynthesis|major histocompatibility complex class II biosynthetic process|MHC class II anabolism|MHC class II synthesis|MHC class II formation|MHC class II biosynthesis The chemical reactions and pathways resulting in the formation of major histocompatibility protein class II. GO:0060960 cardiac neuron fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060960 heart neuron fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron of the heart. GO:0060961 phospholipase D inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0060961 Stops, prevents or reduces the activity of a phospholipase D, an enzyme that catalyzes the reaction: a phosphatidylcholine + H2O = choline + a phosphatidate. GO:0060962 regulation of ribosomal protein gene transcription by RNA polymerase II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060962 regulation of ribosomal protein gene transcription from RNA polymerase II promoter Any process that modulates the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II. GO:0060963 positive regulation of ribosomal protein gene transcription by RNA polymerase II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060963 positive regulation of ribosomal protein gene transcription from RNA polymerase II promoter Any process that increases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II. GO:0045349 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045349 GO:0060964 regulation of gene silencing by miRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060964 regulation of gene silencing by microRNA Any process that modulates the rate, frequency, or extent of the downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: RNA (often mRNA) cleavage or mRNA translational repression. GO:0060965 negative regulation of gene silencing by miRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060965 negative regulation of gene silencing by microRNA Any process that decreases the rate, frequency, or extent of gene silencing by miRNA. UBERON:0003502 neck blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003502 neck (volume) blood vessel|blood vessel of neck|blood vessel of neck (volume) A blood vessel that is part of a neck [Automatically generated definition]. GO:0060966 regulation of gene silencing by RNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060966 Any process that regulates the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes. UBERON:0003503 leg blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003503 blood vessel of leg A blood vessel that is part of a leg [Automatically generated definition]. GO:0060967 negative regulation of gene silencing by RNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060967 Any process that decreases the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes. UBERON:0003500 corneal blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003500 blood vessel of cornea|cornea blood vessel A blood vessel that is part of a cornea [Automatically generated definition]. GO:0060968 regulation of gene silencing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060968 Any process that modulates the rate, frequency, or extent of gene silencing, the transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation. UBERON:0003501 retina blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003501 retinal blood vessel|blood vessel of inner layer of eyeball|blood vessel of retina|tunica interna of eyeball blood vessel|inner layer of eyeball blood vessel|blood vessel of tunica interna of eyeball A blood vessel that is part of a retina [Automatically generated definition]. GO:0060969 negative regulation of gene silencing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060969 Any process that decreases the rate, frequency, or extent of gene silencing, the transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation. CHEBI:71510 anthocyanidin 3,5-di-O-beta-D-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71510 CHEBI:71511 cyanin betaine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71511 CHEBI:71512 1-O-vanilloyl-beta-D-glucose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71512 CHEBI:71513 cyanidin 3,7-di-O-beta-D-glucoside betaine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71513 CHEBI:71515 cyanidin 3-O-beta-D-galactoside betaine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71515 CHEBI:71516 cyanidin 3-O-[beta-D-xylosyl-(1->2)-beta-D-galactoside](1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71516 CHEBI:71517 2,3-bis-O-(geranylgeranyl)-sn-glycero-3-phospho-L-serine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71517 CHEBI:71519 anthocyanidin 3-O-[2-O-(4-coumaroyl)-alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] betaine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71519 CHEBI:71522 anthocyanidin 3-O-[2-O-(4-coumaroyl)-alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] 5-O-beta-D-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71522 CHEBI:71531 gypsogenic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71531 CHEBI:71533 norsolorinate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71533 CHEBI:71534 (S)-averantin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71534 CHEBI:71535 (1'S,5'S)-5'-hydroxyaverantin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71535 CHEBI:71536 (1'S,5'R)-5'-hydroxyaverantin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71536 CHEBI:71537 (1'S,5'S)-averufin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71537 CHEBI:71539 (8Z,11Z,14Z)-3-oxoicosa-8,11,14-trienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71539 CHEBI:71541 (25S)-Delta(4)-dafachronate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71541 CHEBI:71542 (25S)-Delta(7)-dafachronate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71542 CHEBI:71543 rotenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71543 CHEBI:71544 (E)-isopentadec-2-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71544 GO:0035999 tetrahydrofolate interconversion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035999 UniPathway:UPA00193|MetaCyc:PWY-2201 The chemical reactions and pathways by which one-carbon (C1) units are transferred between tetrahydrofolate molecules, to synthesise other tetrahydrofolate molecules. CHEBI:141697 N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminosyl-(2->6)]-N-acetyl-beta-D-galactosaminyl-(1->4)-[N-acetyl-alpha-neuraminosyl-(2->8)-N-acetyl-alpha-neuraminosyl-(2->8)-N-acetyl-alpha-neuraminosyl-(2->3)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_141697 CHEBI:141698 L,L-homocystine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_141698 GO:0035991 nitric oxide sensor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035991 NO sensor activity Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of nitric oxide (NO). GO:0035992 tendon formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035992 The process that gives rise to a tendon. This process pertains to the initial formation of a tendon from unspecified parts. GO:0035993 deltoid tuberosity development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035993 The process whose specific outcome is the progression of the deltoid tuberosity over time, from its formation to the mature structure. The deltoid tuberosity is the region on the shaft of the humerus to which the deltoid muscle attaches. The deltoid tuberosity develops through endochondral ossification in a two-phase process; an initiating tendon-dependent phase, and a muscle-dependent growth phase. GO:0035994 response to muscle stretch biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035994 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a myofibril being extended beyond its slack length. GO:0035995 detection of muscle stretch biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035995 The series of events by which a muscle stretch stimulus is received by a cell and converted into a molecular signal. GO:0035996 rhabdomere microvillus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035996 Thin cylindrical membrane-covered projection on the surface of a rhabdomere. GO:0035997 rhabdomere microvillus membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035997 The portion of the plasma membrane surrounding a microvillus of a rhabdomere. GO:0035998 7,8-dihydroneopterin 3'-triphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035998 UniPathway:UPA00848 7,8-dihydroneopterin 3'-triphosphate biosynthesis|7,8-dihydroneopterin 3'-triphosphate anabolism|7,8-dihydroneopterin 3'-triphosphate synthesis|7,8-dihydroneopterin 3'-triphosphate formation The chemical reactions and pathways resulting in the formation of 7,8-dihydroneopterin 3'-triphosphate. GO:0035990 tendon cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035990 tenocyte differentiation|muscle attachment cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a tendon cell. Tendon cell are elongated fibrocytes in which the cytoplasm is stretched between the collagen fibres of the tendon. Tendon cells have a central cell nucleus with a prominent nucleolus, a well-developed rough endoplasmic reticulum, and are responsible for synthesis and turnover of tendon fibres and ground substance. CHEBI:71540 isoheptadecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71540 CHEBI:71554 PPARgamma agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71554 CHEBI:71556 (25S)-Delta(7)-dafachronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71556 GO:0035988 chondrocyte proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035988 chondrocyte cell proliferation|cartilage cell proliferation The multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population. A chondrocyte is a polymorphic cell that forms cartilage. GO:0035989 tendon development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035989 sinew development The process whose specific outcome is the progression of a tendon over time, from its formation to the mature structure. A tendon is a fibrous, strong, connective tissue that connects muscle to bone or integument and is capable of withstanding tension. Tendons and muscles work together to exert a pulling force. GO:0035980 obsolete invasive growth in response to nitrogen limitation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035980 invasive growth in response to nitrogen limitation OBSOLETE. The growth of colonies in filamentous chains of cells as a result of a reduced availability of nitrogen. GO:0035981 tongue muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035981 The process in which a relatively unspecialized cell acquires specialized features of a tongue muscle cell. GO:0035982 obsolete age-dependent behavioral decline biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035982 behavioral aging|age-related behavioral decline|age-dependent behavioural decline OBSOLETE. A developmental process that arises as an organism progresses toward the end of its lifespan that results in a decline in behavioral activities such as locomotory behavior, and learning or memory. GO:0035983 response to trichostatin A biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035983 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichostatin A stimulus. GO:0035984 cellular response to trichostatin A biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035984 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichostatin A stimulus. GO:0035985 senescence-associated heterochromatin focus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035985 senescence-associated heterochromatin foci|SAHF A transcriptionally-silent heterochromatin structure present in senescent cells. Contains the condensed chromatin of one chromosome and is enriched for histone modifications. Thought to repress expression of proliferation-promoting genes. GO:0035986 senescence-associated heterochromatin focus assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035986 senescence-associated heterochromatin focus formation|SAHF formation|senescence-associated heterochromatin foci formation The assembly of chromatin into senescence-associated heterochromatin foci (SAHF), transcriptionally-silent heterochromatin structures present in senescent cells, containing the condensed chromatin of one chromosome, and enriched for histone modifications. Formation of these chromatin structures is thought to repress expression of proliferation-promoting genes. GO:0035987 endodermal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035987 endoderm cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo. CHEBI:71550 lathosterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71550 CHEBI:71551 EC 3.5.1.23 (ceramidase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71551 CHEBI:71563 all-cis-8,11,14,17-icosatetraenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71563 CHEBI:71566 precorrin-7 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71566 CHEBI:71567 (25S)-cholestenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71567 GO:0035977 protein deglycosylation involved in glycoprotein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035977 The removal of sugar residues from a glycosylated protein that contributes to the breakdown of a glycoprotein. GO:0035978 histone H2A-S139 phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035978 histone H2A.x phosphorylation at S139 The modification of histone H2A by the addition of an phosphate group to a serine residue at position 139 of the histone. GO:0035979 histone kinase activity (H2A-S139 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035979 histone kinase activity (H2A.x-S139 specific) Catalysis of the transfer of a phosphate group to the serine-139 residue of the C-terminal tail of histone H2A. GO:0035970 peptidyl-threonine dephosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035970 The removal of phosphoric residues from peptidyl-O-phospho-L-threonine to form peptidyl-threonine. GO:0035971 peptidyl-histidine dephosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035971 The removal of phosphoric residues from peptidyl-O-phospho-L-histidine to form peptidyl-histidine. GO:0035972 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035972 GO:0035973 aggrephagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035973 Selective degradation of protein aggregates by macroautophagy. GO:0035974 meiotic spindle pole body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035974 The microtubule organizing center that forms as part of the meiotic cell cycle; functionally homologous to the animal cell centrosome. GO:0035975 carbamoyl phosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035975 carbamoyl phosphate degradation|carbamoyl phosphate catabolism|carbamoyl phosphate breakdown The chemical reactions and pathways resulting in the breakdown of carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways. GO:0035976 transcription factor AP-1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035976 transcription factor AP1 complex|AP-1 complex|Activating protein 1 complex|AP1 complex A heterodimeric transcription factor complex composed of proteins from the c-Fos, c-Jun, activating transcription factor (ATF) or JDP families. The subunits contain a basic leucine zipper (bZIP) domain that is essential for dimerization and DNA binding. Jun-Fos heterodimers bind preferentially to a heptamer consensus sequence (TPA responsive element (TRE)), whereas Jun-ATF dimers bind the cyclic AMP responsive element (CRE) to regulate transcription of target genes. CHEBI:71560 (25S)-Delta(4)-dafachronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71560 CHEBI:71574 (8Z,11Z,14Z,17Z)-3-oxoicosatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71574 CHEBI:71576 30-hydroxy-11-oxo-beta-amyrin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71576 CHEBI:71577 glycyrrhetaldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71577 CHEBI:71578 cyclic di-AMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71578 CHEBI:71579 methyl red(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71579 GO:0035966 response to topologically incorrect protein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035966 response to misfolded or unfolded protein Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure. GO:0035967 cellular response to topologically incorrect protein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035967 cellular response to misfolded or unfolded protein Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure. GO:0035968 obsolete regulation of sterol import by regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035968 regulation of sterol influx by regulation of transcription from Pol II promoter|regulation of sterol uptake by regulation of transcription from RNA polymerase II promoter|regulation of sterol uptake by regulation of transcription from Pol II promoter|regulation of sterol influx by regulation of transcription from RNA polymerase II promoter|regulation of sterol import by regulation of transcription from Pol II promoter OBSOLETE. Any process that modulates the frequency, rate or extent of sterol import, by regulation of transcription from an RNA polymerase II promoter. GO:0035969 obsolete positive regulation of sterol import by positive regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035969 positive regulation of sterol influx by upregulation of transcription from RNA polymerase II promoter|positive regulation of sterol uptake by activation of transcription from RNA polymerase II promoter|positive regulation of sterol influx by up regulation of transcription from RNA polymerase II promoter|positive regulation of sterol influx by positive regulation of transcription from RNA polymerase II promoter|positive regulation of sterol import by activation of transcription from RNA polymerase II promoter|positive regulation of sterol import by up regulation of transcription from RNA polymerase II promoter|positive regulation of sterol influx by stimulation of transcription from RNA polymerase II promoter|positive regulation of sterol influx by activation of transcription from RNA polymerase II promoter|positive regulation of sterol import by positive regulation of transcription from Pol II promoter|positive regulation of sterol uptake by up regulation of transcription from RNA polymerase II promoter|positive regulation of sterol influx by up-regulation of transcription from RNA polymerase II promoter|positive regulation of sterol uptake by upregulation of transcription from RNA polymerase II promoter|positive regulation of sterol uptake by positive regulation of transcription from RNA polymerase II promoter|positive regulation of sterol import by upregulation of transcription from RNA polymerase II promoter|positive regulation of sterol import by stimulation of transcription from RNA polymerase II promoter|positive regulation of sterol import by up-regulation of transcription from RNA polymerase II promoter|positive regulation of sterol uptake by stimulation of transcription from RNA polymerase II promoter|positive regulation of sterol uptake by up-regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that activates or increases the frequency, rate or extent of sterol import by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:0035960 obsolete regulation of ergosterol biosynthetic process by regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035960 regulation of ergosterol formation by regulation of transcription from RNA polymerase II promoter|regulation of ergosterol synthesis by regulation of transcription from RNA polymerase II promoter|regulation of ergosterol anabolism by regulation of transcription from RNA polymerase II promoter|regulation of ergosterol biosynthesis by regulation of transcription from Pol II promoter|regulation of ergosterol biosynthetic process by regulation of transcription from Pol II promoter|regulation of ergosterol biosynthesis by regulation of transcription from RNA polymerase II promoter|regulation of ergosterol anabolism by regulation of transcription from Pol II promoter|regulation of ergosterol synthesis by regulation of transcription from Pol II promoter|regulation of ergosterol formation by regulation of transcription from Pol II promoter OBSOLETE. Any process that modulates the frequency, rate or extent of ergosterol biosynthetic process by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:0035961 obsolete positive regulation of ergosterol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035961 positive regulation of ergosterol formation by up regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol anabolism by positive regulation of transcription from Pol II promoter|positive regulation of ergosterol anabolism by positive regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol biosynthesis by positive regulation of transcription from Pol II promoter|positive regulation of ergosterol synthesis by upregulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol synthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol biosynthesis by upregulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol anabolism by upregulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol biosynthetic process by positive regulation of transcription from Pol II promoter|positive regulation of ergosterol biosynthesis by up-regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol anabolism by up-regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol formation by positive regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol biosynthetic process by stimulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol synthesis by up-regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol biosynthetic process by upregulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol biosynthetic process by up-regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol formation by up-regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol anabolism by up regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol biosynthesis by up regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol formation by positive regulation of transcription from Pol II promoter|positive regulation of ergosterol biosynthetic process by activation of transcription from RNA polymerase II promoter|positive regulation of ergosterol synthesis by positive regulation of transcription from Pol II promoter|positive regulation of ergosterol synthesis by up regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol formation by upregulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol biosynthetic process by up regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that activates or increases the frequency, rate or extent of ergosterol biosynthesis by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:0035962 response to interleukin-13 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035962 response to IL-13 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-13 stimulus. CHEBI:141668 L-tyrosinal(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_141668 GO:0035963 cellular response to interleukin-13 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035963 cellular response to IL-13 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-13 stimulus. GO:0035964 COPI-coated vesicle budding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035964 COPI vesicle budding The evagination of a Golgi membrane, resulting in formation of a COPI-coated vesicle. GO:0035965 cardiolipin acyl-chain remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035965 diphosphatidylglycerol remodeling|cardiolipin maturation|cardiolipin acyl-chain remodelling Remodeling the acyl chains of premature (de novo synthesized) cardiolipin (1,3-bis(3-phosphatidyl)glycerol), through sequential deacylation and re-acylation reactions, to generate mature cardiolipin containing high-levels of unsaturated fatty acids. CHEBI:71570 (25R)-Delta(4)-dafachronate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71570 CHEBI:71572 (2R)-3-(3,4-dihydroxyphenyl)lactic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71572 CHEBI:71573 UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71573 CHEBI:71586 (3E,5Z)-tetradecadienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71586 CHEBI:71587 cyanidin 3-O-[beta-D-xylosyl-(1->2)-beta-D-galactoside] biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71587 CHEBI:71589 all-cis-icosa-8,11,14-trienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71589 GO:0035955 obsolete negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035955 negative regulation of dipeptide transport by down regulation of transcription from RNA polymerase II promoter|negative regulation of dipeptide transport by downregulation of transcription from RNA polymerase II promoter|negative regulation of dipeptide transport by down-regulation of transcription from RNA polymerase II promoter|negative regulation of dipeptide transport by negative regulation of transcription from Pol II promoter|negative regulation of dipeptide transport by inhibition of transcription from RNA polymerase II promoter OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of dipeptide transport by stopping, preventing or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:0035956 obsolete regulation of starch catabolic process by regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035956 regulation of starch degradation by regulation of transcription from RNA polymerase II promoter|regulation of starch degradation by regulation of transcription from Pol II promoter|regulation of starch catabolic process by regulation of transcription from Pol II promoter|regulation of starch catabolism by regulation of transcription from RNA polymerase II promoter|regulation of starch catabolism by regulation of transcription from Pol II promoter|regulation of starch breakdown by regulation of transcription from Pol II promoter|regulation of starch breakdown by regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that modulates the frequency, rate or extent of the breakdown of starch, by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:0035957 obsolete positive regulation of starch catabolic process by positive regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035957 positive regulation of starch degradation by regulation of transcription from Pol II promoter|positive regulation of starch breakdown by regulation of transcription from Pol II promoter|positive regulation of starch degradation by regulation of transcription from RNA polymerase II promoter|positive regulation of starch catabolic process by regulation of transcription from Pol II promoter|positive regulation of starch catabolism by regulation of transcription from RNA polymerase II promoter|positive regulation of starch catabolism by regulation of transcription from Pol II promoter|positive regulation of starch breakdown by regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that activates or increases the frequency, rate or extent of the breakdown of starch, by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:0035958 obsolete regulation of glyoxylate cycle by regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035958 regulation of glyoxylate bypass by regulation of transcription from RNA polymerase II promoter|regulation of glyoxylate cycle by regulation of transcription from Pol II promoter|regulation of glyoxylate bypass by regulation of transcription from Pol II promoter OBSOLETE. Any process that modulates the frequency, rate or extent of the glyoxylate cycle by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:0035959 obsolete positive regulation of glyoxylate cycle by positive regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035959 positive regulation of glyoxylate bypass by up-regulation of transcription from RNA polymerase II promoter|positive regulation of glyoxylate cycle by positive regulation of transcription from Pol II promoter|positive regulation of glyoxylate cycle by stimulation of transcription from RNA polymerase II promoter|positive regulation of glyoxylate cycle by upregulation of transcription from RNA polymerase II promoter|positive regulation of glyoxylate cycle by up-regulation of transcription from RNA polymerase II promoter|positive regulation of glyoxylate bypass by positive regulation of transcription from Pol II promoter|positive regulation of glyoxylate bypass by upregulation of transcription from RNA polymerase II promoter|positive regulation of glyoxylate bypass by up regulation of transcription from RNA polymerase II promoter|positive regulation of glyoxylate bypass by positive regulation of transcription from RNA polymerase II promoter|positive regulation of glyoxylate cycle by activation of transcription from RNA polymerase II promoter|positive regulation of glyoxylate cycle by up regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that activates or increases the frequency, rate or extent of the glyoxylate cycle by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:0035950 obsolete regulation of oligopeptide transport by regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035950 regulation of oligopeptide transport by regulation of transcription from Pol II promoter OBSOLETE. Any process that modulates the frequency, rate or extent of oligopeptide transport, by regulation of transcription from an RNA polymerase II promoter. GO:0035951 obsolete positive regulation of oligopeptide transport by positive regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035951 positive regulation of oligopeptide transport by positive regulation of transcription from Pol II promoter|positive regulation of oligopeptide transport by upregulation of transcription from RNA polymerase II promoter|positive regulation of oligopeptide transport by stimulation of transcription from RNA polymerase II promoter|positive regulation of oligopeptide transport by up-regulation of transcription from RNA polymerase II promoter|positive regulation of oligopeptide transport by activation of transcription from RNA polymerase II promoter|positive regulation of oligopeptide transport by up regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that activates or increases the frequency, rate or extent of oligopeptide transport by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:0035952 obsolete negative regulation of oligopeptide transport by negative regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035952 negative regulation of oligopeptide transport by inhibition of transcription from RNA polymerase II promoter|negative regulation of oligopeptide transport by down-regulation of transcription from RNA polymerase II promoter|negative regulation of oligopeptide transport by negative regulation of transcription from Pol II promoter|negative regulation of oligopeptide transport by downregulation of transcription from RNA polymerase II promoter|negative regulation of oligopeptide transport by down regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of oligopeptide transport by stopping, preventing or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:0035953 obsolete regulation of dipeptide transport by regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035953 regulation of dipeptide transport by regulation of transcription from Pol II promoter OBSOLETE. Any process that modulates the frequency, rate or extent of dipeptide transport, by regulation of transcription from an RNA polymerase II promoter. GO:0035954 obsolete positive regulation of dipeptide transport by positive regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035954 positive regulation of dipeptide transport by upregulation of transcription from RNA polymerase II promoter|positive regulation of dipeptide transport by up regulation of transcription from RNA polymerase II promoter|positive regulation of dipeptide transport by stimulation of transcription from RNA polymerase II promoter|positive regulation of dipeptide transport by up-regulation of transcription from RNA polymerase II promoter|positive regulation of dipeptide transport by activation of transcription from RNA polymerase II promoter|positive regulation of dipeptide transport by positive regulation of transcription from Pol II promoter OBSOLETE. Any process that activates or increases the frequency, rate or extent of dipeptide transport by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. CHEBI:71580 c-GMP-AMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71580 CHEBI:71583 anthocyanidin glycoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71583 CHEBI:71584 cyanidin 3,7-di-O-beta-D-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71584 GO:0070273 phosphatidylinositol-4-phosphate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070273 Interacting selectively and non-covalently with phosphatidylinositol-4-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' position. GO:0070274 RES complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070274 pre-mRNA retention and splicing complex A protein complex that is required for efficient splicing, and prevents leakage of unspliced pre-mRNAs from the nucleus (named for pre-mRNA REtention and Splicing). In Saccharomyces, the complex consists of Ist3p, Bud13p, and Pml1p. GO:0070271 obsolete protein complex biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070271 protein complex biogenesis and assembly OBSOLETE. A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a protein complex. Includes the synthesis of non-protein components, and those protein modifications that are involved in synthesis or assembly of the complex. GO:0070272 obsolete proton-transporting ATP synthase complex biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070272 F-type ATPase complex biogenesis OBSOLETE. The biogenesis of a proton-transporting ATP synthase (also known as F-type ATPase), a two-sector ATPase found in the inner membrane of mitochondria and chloroplasts, and in bacterial plasma membranes. Includes the synthesis of constituent proteins and their aggregation, arrangement and bonding together. CHEBI:22501 aminodiol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22501 GO:0070270 obsolete mitotic catastrophe biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070270 cell death preceded by multinucleation|cell death occurring during metaphase|mitotic catastrophe OBSOLETE. A type of programmed cell death that occurs during or shortly after a dysregulated or failed mitosis and can be accompanied by morphological alterations including micronucleation and multinucleation. CHEBI:22502 2-aminoethyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22502 CHEBI:22500 aminobutanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22500 CHEBI:22506 aminoglycan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22506 GO:0070279 vitamin B6 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070279 Interacting selectively and non-covalently with any of the vitamin B6 compounds: pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate. GO:0070277 iodide oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070277 The chemical reactions and pathways by which iodide is converted to diiodine, with the concomitant loss of electrons. GO:0070278 extracellular matrix constituent secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070278 ECM constituent secretion|ECM secretion The controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell. CHEBI:22507 aminoglycoside antibiotic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22507 GO:0070275 aerobic ammonia oxidation to nitrite via pyruvic oxime biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070275 MetaCyc:PWY-2242 The metabolic process in which ammonia (NH3) is oxidized to nitrite (NO2) in the presence of oxygen. Hydroxylamine is produced enzymatically, and, in the presence of pyruvate, forms pyruvic oxime in a spontaneous, non-enzymatic reaction; pyruvic oxime is then converted to nitrite. GO:0070276 halogen metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070276 halogen metabolism The chemical reactions and pathways involving any halogen, elements of Group VII; includes metabolism of halogen-containing compounds. GO:0070262 peptidyl-serine dephosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070262 The removal of phosphoric residues from peptidyl-O-phospho-L-serine to form peptidyl-serine. GO:0070263 external side of fungal-type cell wall biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070263 The side of the fungal-type cell wall that is opposite to the side that faces the cell and its contents. GO:0070260 5'-tyrosyl-DNA phosphodiesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070260 Catalysis of the hydrolysis of 5'-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase II and DNA. GO:0070261 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0070261 CHEBI:22512 aminoimidazole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22512 GO:0070268 cornification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070268 A type of programmed cell death that occurs in the epidermis, morphologically and biochemically distinct from apoptosis. It leads to the formation of corneocytes, i.e. dead keratinocytes containing an amalgam of specific proteins (e.g., keratin, loricrin, SPR and involucrin) and lipids (e.g., fatty acids and ceramides), which are necessary for the function of the cornified skin layer (mechanical resistance, elasticity, water repellence and structural stability). GO:0070269 pyroptosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070269 A caspase-1-dependent cell death subroutine that is associated with the generation of pyrogenic mediators such as IL-1beta and IL-18. GO:0070266 necroptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070266 programmed necrotic cell death|induction of necroptosis|programmed necrosis|TNF-induced necroptosis|induction of necroptosis of activated-T cells|activation of necroptosis in response to extracellular signals|extracellular signal-induced necroptosis|necroptosis|induction of necroptosis by extracellular signals|establishment of necroptosis of activated-T cells|activation of necroptosis of activated-T cells|RIPK1-mediated regulated necrosis|activation of necroptosis by extracellular signals|activation of necroptosis|establishment of necroptosis|parthanatos|PARP-dependent cell death A programmed necrotic cell death process which begins when a cell receives a signal (e.g. a ligand binding to a death receptor or to a Toll-like receptor), and proceeds through a series of biochemical events (signaling pathways), characterized by activation of receptor-interacting serine/threonine-protein kinase 1 and/or 3 (RIPK1/3, also called RIP1/3) and by critical dependence on mixed lineage kinase domain-like (MLKL), and which typically lead to common morphological features of necrotic cell death. The process ends when the cell has died. The process is divided into a signaling phase, and an execution phase, which is triggered by the former. GO:0070267 oncosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070267 A cellular process that results in swelling of the cell body, and that is morphologically characteristic of necrotic cell death. GO:0070264 transcription factor TFIIIE complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070264 A transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIE contains a specific subset of ribosomal proteins. GO:0070265 necrotic cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070265 necrosis|cellular necrosis A type of cell death that is morphologically characterized by an increasingly translucent cytoplasm, swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. Necrotic cells do not fragment into discrete corpses as their apoptotic counterparts do. Moreover, their nuclei remain intact and can aggregate and accumulate in necrotic tissues. GO:0070295 renal water absorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070295 nephron water absorption|renal water reabsorption A renal system process in which water is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures. GO:0070296 sarcoplasmic reticulum calcium ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070296 The directed movement of calcium ions (Ca2+) into, out of or within the sarcoplasmic reticulum. GO:0070293 renal absorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070293 renal reabsorption|nephron absorption A renal system process in which water, ions, glucose and proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686). GO:0070294 renal sodium ion absorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070294 nephron sodium ion absorption|renal sodium ion reabsorption A renal system process in which sodium ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures. GO:0070291 N-acylethanolamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070291 NAE metabolism|NAE metabolic process|N-acylethanolamine metabolism The chemical reactions and pathways involving N-acylethanolamines. An N-acylethanolamine is an ethanolamine substituted at nitrogen by an acyl group. GO:0070292 N-acylphosphatidylethanolamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070292 N-acylphosphatidylethanolamine metabolism|NAPE metabolic process|NAPE metabolism The chemical reactions and pathways involving N-acylphosphatidylethanolamines. An N-acylphosphatidylethanolamine is a phosphatidylethanolamine substituted at nitrogen by an acyl group. GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0070290 Reactome:R-HSA-2466831|EC:3.1.4.4 N-acyl-phosphatidylethanolamine-specific phospholipase D activity|NAPE-specific phospholipase D activity Catalysis of the release of N-acylethanolamine from N-acyl-phosphatidylethanolamine (NAPE) to generate N-acylethanolamine (NAE). NCBITaxon:33511 Deuterostomia organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_33511 deuterostomes GO:0070299 positive regulation of phosphorelay signal transduction system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070299 positive regulation of two-component signal transduction system (phosphorelay)|positive regulation of histidyl-aspartyl phosphorelay|up regulation of two-component signal transduction|activation of two-component signal transduction|stimulation of two-component signal transduction|up-regulation of two-component signal transduction|upregulation of two-component signal transduction Any process that activates or increases the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system. GO:0070297 regulation of phosphorelay signal transduction system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070297 regulation of two-component signal transduction system|regulation of histidyl-aspartyl phosphorelay|regulation of two-component signal transduction system (phosphorelay) Any process that modulates the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system. GO:0070298 negative regulation of phosphorelay signal transduction system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070298 downregulation of two-component signal transduction|negative regulation of two-component signal transduction system (phosphorelay)|down-regulation of two-component signal transduction|inhibition of two-component signal transduction|down regulation of two-component signal transduction|negative regulation of histidyl-aspartyl phosphorelay Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system. GO:0070284 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070284 ThiC|HMP-P synthase activity Catalysis of the reaction: 5-aminoimidazole ribonucleotide + S-adenosylmethionine = 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate + 5'deoxyadenosine. GO:0070285 pigment cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070285 The process whose specific outcome is the progression of a pigment cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a pigment cell fate. GO:0070282 pyridoxine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070282 Interacting selectively and non-covalently with pyridoxine, 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol, a form of vitamin B6. GO:0070283 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0070283 GO:0070280 pyridoxal binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070280 Interacting selectively and non-covalently with pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde, a form of vitamin B6. GO:0070281 pyridoxamine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070281 Interacting selectively and non-covalently with pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, a form of vitamin B6. GO:0070288 ferritin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070288 A protein complex that binds iron and acts as a major iron storage system. Intracellular and extracellular ferritin complexes have different ratios of two types of ferritin monomer, the L (light) chain and H (heavy) chain. GO:0070289 extracellular ferritin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070289 serum ferritin complex A ferritin complex located in the extracellular region. Extracellular ferritin complexes contain L (light) chains but few or no H (heavy) chains. GO:0070286 axonemal dynein complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070286 dynein arm assembly The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein complex, a dynein complex found in eukaryotic cilia and flagella, in which the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion. GO:0070287 ferritin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070287 ferritin complex receptor activity Combining with ferritin, and delivering ferritin into the cell via endocytosis. CHEBI:71500 cyclic di-AMP(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71500 CHEBI:71501 c-GMP-AMP(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71501 CHEBI:71502 beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71502 CHEBI:71505 anthocyanidin 3-O-[6-O-(4-hydroxycinnamoyl)-beta-D-glucoside] biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71505 CHEBI:71506 anthocyanidin 3-O-beta-D-sambubioside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71506 CHEBI:71507 anthocyanidin 5-O-beta-D-glucoside 3-O-beta-D-sambubioside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71507 CHEBI:71509 anthocyanidin 3-O-sophoroside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71509 GO:0045230 capsule organization biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0045230 capsule organisation|capsule organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the capsule, a protective structure surrounding some species of bacteria and fungi. CHEBI:22586 antioxidant biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22586 GO:1901969 positive regulation of polynucleotide 3'-phosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901969 up-regulation of 2'(3')-polynucleotidase activity|activation of polynucleotide 3'-phosphohydrolase activity|upregulation of deoxyribonucleate 3'-phosphatase activity|up regulation of 5'-polynucleotidekinase 3'-phosphatase activity|activation of polynucleotide 3'-phosphatase activity|up-regulation of polynucleotide 3'-phosphatase activity|positive regulation of 5'-polynucleotidekinase 3'-phosphatase activity|up regulation of DNA 3'-phosphatase activity|up-regulation of polynucleotide 3'-phosphohydrolase activity|activation of 2'(3')-polynucleotidase activity|positive regulation of DNA 3'-phosphatase activity|activation of 5'-polynucleotidekinase 3'-phosphatase activity|positive regulation of 2'(3')-polynucleotidase activity|activation of DNA 3'-phosphatase activity|up regulation of deoxyribonucleate 3'-phosphatase activity|positive regulation of deoxyribonucleate 3'-phosphatase activity|up regulation of 2'(3')-polynucleotidase activity|up-regulation of 5'-polynucleotidekinase 3'-phosphatase activity|up regulation of polynucleotide 3'-phosphatase activity|upregulation of polynucleotide 3'-phosphohydrolase activity|up-regulation of DNA 3'-phosphatase activity|activation of deoxyribonucleate 3'-phosphatase activity|upregulation of 2'(3')-polynucleotidase activity|upregulation of 5'-polynucleotidekinase 3'-phosphatase activity|up-regulation of deoxyribonucleate 3'-phosphatase activity|upregulation of polynucleotide 3'-phosphatase activity|up regulation of polynucleotide 3'-phosphohydrolase activity|upregulation of DNA 3'-phosphatase activity|positive regulation of polynucleotide 3'-phosphohydrolase activity Any process that activates or increases the frequency, rate or extent of polynucleotide 3'-phosphatase activity. CHEBI:22583 antifeedant biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22583 GO:1901967 negative regulation of cellular response to iron ion starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901967 downregulation of cellular response to iron ion starvation|down regulation of cellular response to iron ion starvation|inhibition of cellular response to iron ion starvation|down-regulation of cellular response to iron ion starvation Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to iron ion starvation. GO:1901968 regulation of polynucleotide 3'-phosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901968 regulation of DNA 3'-phosphatase activity|regulation of deoxyribonucleate 3'-phosphatase activity|regulation of 2'(3')-polynucleotidase activity|regulation of polynucleotide 3'-phosphohydrolase activity|regulation of 5'-polynucleotidekinase 3'-phosphatase activity Any process that modulates the frequency, rate or extent of polynucleotide 3'-phosphatase activity. GO:1901965 endoplasmic reticulum to chloroplast transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901965 ER to chloroplast transport The directed movement of substances from endoplasmic reticulum to chloroplast. CHEBI:22587 antiviral agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22587 GO:1901966 regulation of cellular response to iron ion starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901966 Any process that modulates the frequency, rate or extent of cellular response to iron ion starvation. GO:1901963 regulation of cell proliferation involved in outflow tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901963 Any process that modulates the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis. GO:0045237 CXCR1 chemokine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045237 CXCR1 chemokine receptor ligand Interacting selectively and non-covalently with the CXCR1 chemokine receptor. GO:1901964 positive regulation of cell proliferation involved in outflow tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901964 up regulation of cell proliferation involved in outflow tract morphogenesis|upregulation of cell proliferation involved in outflow tract morphogenesis|up-regulation of cell proliferation involved in outflow tract morphogenesis|activation of cell proliferation involved in outflow tract morphogenesis Any process that activates or increases the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis. GO:0045238 CXCR2 chemokine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045238 CXCR2 chemokine receptor ligand Interacting selectively and non-covalently with the CXCR2 chemokine receptor. GO:1901961 isobutanol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901961 isobutanol synthesis|isobutanol formation|isobutanol biosynthesis|isobutanol anabolism The chemical reactions and pathways resulting in the formation of isobutanol. GO:0045235 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045235 GO:0045236 CXCR chemokine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045236 CXC chemokine receptor ligand|C-X-C chemokine receptor ligand|alpha chemokine receptor binding|alpha chemokine receptor ligand Interacting selectively and non-covalently with a chemokine receptor in the CXCR family. GO:1901962 S-adenosyl-L-methionine transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901962 S-adenosylmethionine transmembrane transport|SAM transmembrane transport The directed movement of S-adenosyl-L-methionine across a membrane. GO:0045233 obsolete natural killer cell receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045233 Ly49i|NK cell receptor activity|natural killer cell receptor activity OBSOLETE. A receptor found on the surface of natural killer cells which binds Class I MHC antigens and is required for activation of NK activity. It belongs to the Ly49i family. GO:1901960 isobutanol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901960 isobutanol metabolism The chemical reactions and pathways involving isobutanol. GO:0045234 protein palmitoleylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045234 protein amino acid palmitoleylation The covalent attachment of a palmitoleyl group to a protein. GO:0045231 slime layer organization biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0045231 slime layer organization and biogenesis|slime layer organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a slime layer. A slime layer is an easily removed, diffuse, unorganized layer of extracellular material that surrounds a cell. GO:0045232 S-layer organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045232 S-layer organization and biogenesis|S-layer organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an S-layer enveloping the cell. The S-layer is a crystalline protein layer surrounding some bacteria. CHEBI:22580 anthraquinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22580 UBERON:0003571 trachea connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003571 connective tissue of windpipe|connective tissue of trachea A portion of connective tissue that is part of a trachea. GO:0060870 cell wall disassembly involved in floral organ abscission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060870 A cellular process that results in the breakdown of the cell wall that contributes to the process of floral organ abscission. UBERON:0003572 chest connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003572 connective tissue of anterior thoracic region|anterolateral part of thorax portion of connective tissue|textus connectivus of chest|front of thorax connective tissue|textus connectivus of front of thorax|textus connectivus of anterolateral part of thorax|anterolateral part of thorax textus connectivus|portion of connective tissue of chest|portion of connective tissue of front of thorax|anterior thoracic region connective tissue|connective tissue of anterolateral part of thorax|anterior thoracic region portion of connective tissue|portion of connective tissue of anterior thoracic region|front of thorax portion of connective tissue|anterior thoracic region textus connectivus|chest portion of connective tissue|anterolateral part of thorax connective tissue|textus connectivus of anterior thoracic region|connective tissue of chest|front of thorax textus connectivus|connective tissue of front of thorax|chest textus connectivus|portion of connective tissue of anterolateral part of thorax A portion of connective tissue that is part of a chest [Automatically generated definition]. GO:0060871 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0060871 GO:0060872 semicircular canal development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060872 The progression of the semicircular canal from its initial formation to the mature structure. OBO:GOCHE_76741 substance with EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_76741 UBERON:0003570 respiratory system connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003570 portion of connective tissue of respiratory system|textus connectivus of apparatus respiratorius|apparatus respiratorius connective tissue|textus connectivus of respiratory system|apparatus respiratorius portion of connective tissue|portion of connective tissue of apparatus respiratorius|apparatus respiratorius textus connectivus|connective tissue of respiratory system|respiratory system portion of connective tissue|respiratory system textus connectivus|connective tissue of apparatus respiratorius A portion of connective tissue that is part of a respiratory system [Automatically generated definition]. GO:0060873 anterior semicircular canal development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060873 The progession of the anterior semicircular canal from its initial formation to the mature structure. GO:0060874 posterior semicircular canal development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060874 The progession of the posterior semicircular canal from its initial formation to the mature structure. GO:0060875 lateral semicircular canal development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060875 The progession of the lateral semicircular canal from its initial formation to the mature structure. GO:0060876 semicircular canal formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060876 The developmental process pertaining to the initial formation of the semicircular canal from the otic vesicle. This process begins with the regionalization of the vesicle that specifies the area where the vesicles will form and continues through the process of fusion which forms the initial tubes. GO:0045239 tricarboxylic acid cycle enzyme complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0045239 TCA cycle enzyme complex Any of the heteromeric enzymes that act in the TCA cycle. GO:0060877 regionalization involved in semicircular canal formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060877 The pattern specification process that results in the subdivision of the otic epithelium in space to define an area or volume in which cells will differentiate to give rise to the semicircular canals. GO:0060878 pouch outgrowth involved in semicircular canal formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060878 The morphogenetic process in which an epithelial sheet bends along a linear axis and gives rise to a pouch that will form a semicircular canal. UBERON:0003579 shoulder connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003579 portion of connective tissue of shoulder|textus connectivus of shoulder|shoulder portion of connective tissue|shoulder textus connectivus|connective tissue of shoulder A portion of connective tissue that is part of a shoulder [Automatically generated definition]. GO:0060879 semicircular canal fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060879 Creation of the central hole of the semicircular canal by sealing the edges of the pouch that forms during the process of semicircular canal formation. UBERON:0003577 knee connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003577 knee portion of connective tissue|connective tissue of knee A portion of connective tissue that is part of a knee [Automatically generated definition]. UBERON:0003578 pedal digit connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003578 digitus pedis textus connectivus|connective tissue of foot digit|foot digit connective tissue|foot digit connective tissue|connective tissue of toe|connective tissue of digitus pedis|connective tissue of digit of foot|hind limb digit connective tissue A portion of connective tissue that is part of a toe [Automatically generated definition]. UBERON:0003575 wrist connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003575 connective tissue of wrist|connective tissue of carpal region|carpal region connective tissue A portion of connective tissue that is part of a wrist [Automatically generated definition]. UBERON:0003576 hip connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003576 connective tissue of hip|connective tissue of regio coxae|connective tissue of hip region A portion of connective tissue that is part of a hip [Automatically generated definition]. UBERON:0003573 arm connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003573 A portion of connective tissue that is part of an arm [Automatically generated definition]. UBERON:0003574 elbow connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003574 textus connectivus of cubital region|connective tissue of cubital region|connective tissue of elbow A portion of connective tissue that is part of a elbow [Automatically generated definition]. GO:0045240 dihydrolipoyl dehydrogenase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045240 alpha-ketoglutarate dehydrogenase complex|2-oxoglutarate dehydrogenase complex A protein complex that possesses alpha-ketoglutarate dehydrogenase activity. GO:0045241 cytosolic alpha-ketoglutarate dehydrogenase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045241 2-oxoglutarate dehydrogenase complex Cytosolic complex that possesses alpha-ketoglutarate dehydrogenase activity. CHEBI:22595 arabinonate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22595 GO:1901978 positive regulation of cell cycle checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901978 positive regulation of G1/S checkpoint|up regulation of cell cycle checkpoint|activation of cell cycle checkpoint|positive regulation of G1/S transition checkpoint|up-regulation of cell cycle checkpoint|upregulation of cell cycle checkpoint Any process that activates or increases the frequency, rate or extent of cell cycle checkpoint. GO:1901979 regulation of inward rectifier potassium channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901979 regulation of Kir channel activity Any process that modulates the frequency, rate or extent of inward rectifier potassium channel activity. UBERON:0003559 hindbrain arachnoid mater biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003559 hindbrain arachnoid mater of neuraxis|arachnoid mater of neuraxis of hindbrain|arachnoid mater of hindbrain|rhombencephalon arachnoid mater|hindbrain arachnoid|arachnoid of hindbrain An arachnoid mater that is part of a hindbrain [Automatically generated definition]. GO:1901976 regulation of cell cycle checkpoint biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_1901976 regulation of G1/S transition checkpoint|regulation of G1/S checkpoint Any process that modulates the frequency, rate or extent of cell cycle checkpoint. CHEBI:22598 arabinonolactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22598 GO:1901977 negative regulation of cell cycle checkpoint biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_1901977 downregulation of cell cycle checkpoint|negative regulation of G1/S checkpoint|negative regulation of G1/S transition checkpoint|down-regulation of cell cycle checkpoint|inhibition of cell cycle checkpoint|down regulation of cell cycle checkpoint Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle checkpoint. CHEBI:22599 arabinose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22599 GO:1901974 glycerate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901974 Enables the transfer of glycerate from one side of a membrane to the other. GO:0045248 cytosolic oxoglutarate dehydrogenase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045248 A cytosolic complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2). GO:1901975 glycerate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901975 The process in which glycerate is transported across a membrane. GO:0045249 cytosol pyruvate dehydrogenase (lipoamide) phosphatase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045249 A cytosolic complex of a regulatory and catalytic subunit that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex. GO:0045246 cytosolic tricarboxylic acid cycle enzyme complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045246 TCA cycle enzyme complex|tricarboxylic acid cycle enzyme complex Any of the heteromeric enzymes, located in the cytosol, that act in the tricarboxylic acid (TCA) cycle. GO:1901972 positive regulation of DNA-5-methylcytosine glycosylase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901972 upregulation of DNA-5-methylcytosine glycosylase activity|up regulation of DNA-5-methylcytosine glycosylase activity|activation of DNA-5-methylcytosine glycosylase activity|up-regulation of DNA-5-methylcytosine glycosylase activity Any process that activates or increases the frequency, rate or extent of DNA-5-methylcytosine glycosylase activity. GO:0045247 cytosolic electron transfer flavoprotein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045247 A protein complex located in the cytosol containing flavin adenine dinucleotide (FAD) that, together with an acyl-CoA dehydrogenase, forms a system that oxidizes an acyl-CoA molecule and reduces ubiquinone and other acceptors. GO:1901973 proline binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901973 Interacting selectively and non-covalently with proline. GO:0045244 succinate-CoA ligase complex (GDP-forming) biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045244 succinyl-CoA synthetase, GDP-forming A heterodimeric enzyme complex, usually composed of an alpha and beta chain. Functions in the TCA cycle, hydrolyzing succinyl-CoA into succinate and CoA, thereby forming GTP. GO:1901970 positive regulation of mitotic sister chromatid separation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901970 up regulation of mitotic sister chromatid separation|up regulation of mitotic chromosome separation|activation of mitotic sister chromatid resolution|activation of mitotic sister chromatid separation|positive regulation of mitotic chromosome separation|up-regulation of sister chromatid separation during mitosis|upregulation of chromosome separation during mitosis|up-regulation of mitotic sister chromatid resolution|activation of mitotic chromosome separation|activation of sister chromatid separation during mitosis|up-regulation of mitotic chromosome separation|up-regulation of mitotic sister chromatid separation|up-regulation of chromosome separation during mitosis|upregulation of mitotic sister chromatid resolution|positive regulation of sister chromatid separation during mitosis|up regulation of sister chromatid separation during mitosis|activation of chromosome separation during mitosis|upregulation of mitotic chromosome separation|upregulation of mitotic sister chromatid separation|positive regulation of chromosome separation during mitosis|up regulation of mitotic sister chromatid resolution|upregulation of sister chromatid separation during mitosis|positive regulation of mitotic sister chromatid resolution|up regulation of chromosome separation during mitosis Any process that activates or increases the frequency, rate or extent of mitotic sister chromatid separation. GO:1901971 regulation of DNA-5-methylcytosine glycosylase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901971 Any process that modulates the frequency, rate or extent of DNA-5-methylcytosine glycosylase activity. GO:0045245 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045245 CHEBI:22593 arabinitol phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22593 GO:0045242 isocitrate dehydrogenase complex (NAD+) biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045242 Complex that possesses isocitrate dehydrogenase (NAD+) activity. CHEBI:22590 arabinan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22590 GO:0045243 cytosolic isocitrate dehydrogenase complex (NAD+) biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045243 isocitrate dehydrogenase complex (NAD+) Cytosolic complex that possesses isocitrate dehydrogenase (NAD+) activity. UBERON:0003560 spinal cord arachnoid mater biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003560 arachnoid mater of neuraxis of spinal cord|arachnoid mater of spinal cord|spinal cord arachnoid|arachnoid of spinal cord|spinal cord arachnoid mater of neuraxis An arachnoid mater that is part of a spinal cord [Automatically generated definition]. GO:0060860 regulation of floral organ abscission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060860 Any process that modulates the rate, frequency, or extent of floral organ abscission, the controlled shedding of floral organs. UBERON:0003561 forebrain dura mater biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003561 dura mater of neuraxis of forebrain|dura mater of forebrain|forebrain dura mater of neuraxis A dura mater that is part of a forebrain. GO:0060861 positive regulation of floral organ abscission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060861 Any process that increases the rate, frequency, or extent of floral organ shedding, the controlled shedding of floral organs. GO:0060862 negative regulation of floral organ abscission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060862 Any process that decreases the rate, frequency, or extent of floral organ abscission, the controlled shedding of floral organs. GO:0060863 regulation of floral organ abscission by signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060863 The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately modulating the rate, or extent of floral organ abscission. GO:0060864 obsolete positive regulation of floral organ abscission by small GTPase mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060864 OBSOLETE. Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals that increases the rate or extent of floral organ abscission. GO:0060865 negative regulation of floral organ abscission by transmembrane receptor protein serine/threonine kinase signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060865 negative regulation of floral organ abscission by transmembrane receptor protein serine/threonine kinase signalling pathway The series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand and contributing to the decrease in the rate or frequency of floral organ abscission. GO:0060866 leaf abscission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060866 The controlled shedding of a leaf. UBERON:0003568 neck connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003568 portion of connective tissue of neck|textus connectivus of neck|connective tissue of neck (volume)|neck portion of connective tissue|neck textus connectivus|neck (volume) portion of connective tissue|neck (volume) connective tissue|connective tissue of neck|textus connectivus of neck (volume)|neck (volume) textus connectivus|portion of connective tissue of neck (volume) A portion of connective tissue that is part of a neck [Automatically generated definition]. GO:0060867 fruit abscission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060867 The controlled shedding of a fruit. UBERON:0003569 leg connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003569 connective tissue of leg|textus connectivus of leg|portion of connective tissue of leg|leg portion of connective tissue|leg textus connectivus A portion of connective tissue that is part of a leg [Automatically generated definition]. GO:0060868 obsolete regulation of vesicle-mediated transport involved in floral organ abscission by small GTPase mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060868 OBSOLETE. Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals that modulates the rate or extent of floral organ abscission. UBERON:0003566 head connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003566 textus connectivus of adult head|textus connectivus of head|head portion of connective tissue|connective tissue of adult head|adult head portion of connective tissue|connective tissue of head|head textus connectivus|adult head connective tissue|adult head textus connectivus|portion of connective tissue of adult head|portion of connective tissue of head A portion of connective tissue that is part of a head [Automatically generated definition]. GO:0060869 transmembrane receptor protein serine/threonine kinase signaling pathway involved in floral organ abscission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060869 transmembrane receptor protein serine/threonine kinase signalling pathway involved in floral organ abscission A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses serine/threonine kinase activity, which contributes to the process of floral organ abscission. UBERON:0003567 abdomen connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003567 connective tissue of abdomen|textus connectivus of abdomen|abdomen portion of connective tissue|portion of connective tissue of abdomen|abdomen textus connectivus A portion of connective tissue that is part of an abdomen [Automatically generated definition]. UBERON:0003564 diencephalon dura mater biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003564 dura mater of neuraxis of interbrain|between brain dura mater of neuraxis|dura mater of neuraxis of between brain|dura mater of between brain|dura mater of diencephalon|dura mater of neuraxis of diencephalon|mature diencephalon dura mater|mature diencephalon dura mater of neuraxis|diencephalon dura mater of neuraxis|dura mater of neuraxis of mature diencephalon|dura mater of mature diencephalon|interbrain dura mater|interbrain dura mater of neuraxis|dura mater of interbrain|between brain dura mater A dura mater that is part of a diencephalon [Automatically generated definition]. UBERON:0003565 hindbrain dura mater biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003565 rhombencephalon dura mater|hindbrain dura mater of neuraxis|dura mater of neuraxis of hindbrain|dura mater of hindbrain A dura mater that is part of a hindbrain [Automatically generated definition]. UBERON:0003562 midbrain dura mater biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003562 dura mater of midbrain|dura mater of neuraxis of midbrain|mesencephalon dura mater|midbrain dura mater of neuraxis A dura mater that is part of a midbrain [Automatically generated definition]. UBERON:0003563 telencephalon dura mater biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003563 telencephalon dura mater of neuraxis|dura mater of neuraxis of telencephalon|dura mater of telencephalon A dura mater that is part of a telencephalon [Automatically generated definition]. GO:0045251 electron transfer flavoprotein complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0045251 ETF complex A protein complex facilitating the electron transfer from an acyl-CoA molecule to ubiquinone via its flavin adenine dinucleotide (FAD) cofactor. Usually contains an alpha and a beta subunit and the structural cofactor adenosine monophosphate (AMP). Part of a system that oxidizes an acyl-CoA molecule and reduces ubiquinone and other acceptors in the electron transport system. CHEBI:22563 anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22563 GO:0045252 oxoglutarate dehydrogenase complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0045252 dihydrolipoamide S-succinyltransferase complex A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2). CHEBI:22562 anilines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22562 GO:0045250 cytosolic pyruvate dehydrogenase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045250 pyruvate dehydrogenase complex (lipoamide) Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). Usually contains fewer subunits than its eukaryotic counterpart; for example, the E. coli complex contains 12 E1 dimers, 8 E2 trimers, and 6 E3 dimers arranged in highly symmetric cubic order. NCBITaxon:1292248 Planarioidea organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_1292248 GO:1901989 positive regulation of cell cycle phase transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901989 up regulation of cell cycle phase transition|activation of cell cycle phase transition|up regulation of cell cycle transition|positive regulation of cell cycle transition|activation of cell cycle transition|up-regulation of cell cycle phase transition|up-regulation of cell cycle transition|upregulation of cell cycle phase transition|upregulation of cell cycle transition Any process that activates or increases the frequency, rate or extent of cell cycle phase transition. UBERON:0003548 forebrain meninges biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003548 forebrain meninx|meninges of forebrain|meninx of forebrain A meninx that is part of a forebrain [Automatically generated definition]. GO:1901987 regulation of cell cycle phase transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901987 regulation of cell cycle transition|cell cycle control Any process that modulates the frequency, rate or extent of cell cycle phase transition. CHEBI:22565 ansamycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22565 GO:1901988 negative regulation of cell cycle phase transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901988 down regulation of cell cycle transition|downregulation of cell cycle transition|down-regulation of cell cycle phase transition|down-regulation of cell cycle transition|negative regulation of cell cycle transition|inhibition of cell cycle phase transition|inhibition of cell cycle transition|down regulation of cell cycle phase transition|downregulation of cell cycle phase transition Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle phase transition. UBERON:0003549 brain pia mater biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003549 brain pia mater of neuraxis|pia mater of neuraxis of brain|pia mater of brain The fibrous membrane forming the innermost of the three coverings that surrounds the brain within the cranial cavity that is firmly attached to the glial capsule. GO:1901985 positive regulation of protein acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901985 upregulation of protein amino acid acetylation|activation of protein acetylation|up-regulation of protein amino acid acetylation|activation of protein amino acid acetylation|up-regulation of protein acetylation|positive regulation of protein amino acid acetylation|upregulation of protein acetylation|up regulation of protein amino acid acetylation|up regulation of protein acetylation Any process that activates or increases the frequency, rate or extent of protein acetylation. GO:0045259 proton-transporting ATP synthase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045259 F1-F0 complex|hydrogen-translocating F-type ATPase complex|hydrogen-transporting ATP synthase complex|proton-transporting F-type ATPase complex A proton-transporting two-sector ATPase complex that catalyzes the phosphorylation of ADP to ATP during oxidative phosphorylation. The complex comprises a membrane sector (F0) that carries out proton transport and a cytoplasmic compartment sector (F1) that catalyzes ATP synthesis by a rotational mechanism; the extramembrane sector (containing 3 a and 3 b subunits) is connected via the d-subunit to the membrane sector by several smaller subunits. Within this complex, the g and e subunits and the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis. This movement is driven by the hydrogen ion electrochemical potential gradient. GO:1901986 response to ketamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901986 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ketamine stimulus. GO:0045257 succinate dehydrogenase complex (ubiquinone) biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045257 The enzyme that catalyzes the oxidation of succinate and ubiquinone to fumarate and ubiquinol; involved in aerobic respiration, repressed in anaerobic respiration. GO:1901983 regulation of protein acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901983 regulation of protein amino acid acetylation Any process that modulates the frequency, rate or extent of protein acetylation. GO:1901984 negative regulation of protein acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901984 down-regulation of protein acetylation|inhibition of protein acetylation|negative regulation of protein amino acid acetylation|down-regulation of protein amino acid acetylation|down regulation of protein acetylation|downregulation of protein amino acid acetylation|downregulation of protein acetylation|down regulation of protein amino acid acetylation|inhibition of protein amino acid acetylation Any process that stops, prevents or reduces the frequency, rate or extent of protein acetylation. GO:0045258 plasma membrane succinate dehydrogenase complex (ubiquinone) biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045258 The enzyme, located in the plasma membrane, that catalyzes the oxidation of succinate and ubiquinone to fumarate and ubiquinol; involved in aerobic respiration, repressed in anaerobic respiration. GO:1901981 phosphatidylinositol phosphate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901981 Interacting selectively and non-covalently with phosphatidylinositol phosphate. GO:0045255 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045255 GO:1901982 maltose binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901982 Interacting selectively and non-covalently with maltose. GO:0045256 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045256 GO:0060890 limb spinous cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060890 The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal spinous cell. NCBITaxon:1292243 Continenticola organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_1292243 GO:0045253 pyruvate dehydrogenase (lipoamide) phosphatase complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0045253 A complex of a regulatory and catalytic subunit that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex. GO:1901980 positive regulation of inward rectifier potassium channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901980 activation of Kir channel activity|upregulation of inward rectifier potassium channel activity|positive regulation of Kir channel activity|up regulation of Kir channel activity|up regulation of inward rectifier potassium channel activity|activation of inward rectifier potassium channel activity|upregulation of Kir channel activity|up-regulation of Kir channel activity|up-regulation of inward rectifier potassium channel activity Any process that activates or increases the frequency, rate or extent of inward rectifier potassium channel activity. GO:0045254 pyruvate dehydrogenase complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0045254 Wikipedia:Pyruvate_dehydrogenase_complex pyruvate dehydrogenase complex (lipoamide)|dihydrolipoyl dehydrogenase complex Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). GO:0060891 limb granular cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060891 The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal granular cell. GO:0060892 limb basal epidermal cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060892 The process in which a cell becomes capable of differentiating autonomously into an limb basal epidermal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. UBERON:0003550 forebrain pia mater biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003550 pia mater of neuraxis of forebrain|pia mater of forebrain|forebrain pia mater of neuraxis A pia mater that is part of a forebrain [Automatically generated definition]. GO:0060893 limb granular cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060893 The process in which a cell becomes capable of differentiating autonomously into an limb granular cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. GO:0060894 limb spinous cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060894 The process in which a cell becomes capable of differentiating autonomously into a limb spinous cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. GO:0060895 retinoic acid receptor signaling pathway involved in spinal cord dorsal/ventral patterning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060895 retinoic acid receptor signalling pathway involved in spinal cord dorsal/ventral patterning The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that contributes to the dorsal ventral patterning of the spinal cord. GO:0070219 cellular sulfide ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070219 cellular sulphide homeostasis|cellular sulfide homeostasis|cellular sulphide ion homeostasis Any process involved in the maintenance of an internal steady state of sulfide ions at the level of a cell. GO:0060896 neural plate pattern specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060896 The developmental process that results in the creation of defined areas or spaces within the neural plate to which cells respond and eventually are instructed to differentiate. GO:0060897 neural plate regionalization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060897 The pattern specification process that results in the subdivision of an axis or axes of the neural plate in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment. GO:0070217 transcription factor TFIIIB complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070217 TFIIIB assembly The aggregation, arrangement and bonding together of a set of components to form a transcription factor TFIIIB complex. GO:0060898 eye field cell fate commitment involved in camera-type eye formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060898 The commitment of neurectodermal cells to cells of the eye field and their capacity to differentiate into eye field cells. Eye field cells are neurectodermal cells that will form the optic placode. GO:0070218 sulfide ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070218 sulphide production|sulphide generation|sulfide production|sulfide generation|sulphide ion homeostasis|sulfide homeostasis|sulphide homeostasis Any process involved in the maintenance of an internal steady state of sulfide ions within an organism or cell. GO:0060899 obsolete regulation of transcription involved in eye field cell fate commitment of camera-type eye biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060899 OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a neurectodermal cell to a specialized neurectodermal cell that will give rise to the optic vesicle. UBERON:0003557 midbrain arachnoid mater biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003557 mesencephalon arachnoid mater|midbrain arachnoid|arachnoid mater of midbrain|arachnoid mater of neuraxis of midbrain|midbrain arachnoid mater of neuraxis|arachnoid of midbrain An arachnoid mater that is part of a midbrain [Automatically generated definition]. GO:0070215 obsolete MDM2 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070215 MDM2 binding OBSOLETE. Interacting selectively and non-covalently with any isoform of the MDM2 protein, a negative regulator of p53. UBERON:0003558 diencephalon arachnoid mater biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003558 arachnoid mater of interbrain|arachnoid mater of neuraxis of interbrain|between brain arachnoid mater|mature diencephalon arachnoid|between brain arachnoid mater of neuraxis|arachnoid mater of diencephalon|arachnoid mater of neuraxis of between brain|interbrain arachnoid mater|arachnoid mater of between brain|arachnoid mater of neuraxis of diencephalon|interbrain arachnoid mater of neuraxis|arachnoid of interbrain|arachnoid of mature diencephalon|between brain arachnoid|diencephalon arachnoid mater of neuraxis|arachnoid of diencephalon|interbrain arachnoid|mature diencephalon arachnoid mater|mature diencephalon arachnoid mater of neuraxis|arachnoid mater of neuraxis of mature diencephalon|arachnoid of between brain|arachnoid mater of mature diencephalon|diencephalon arachnoid An arachnoid mater that is part of a diencephalon [Automatically generated definition]. GO:0070216 obsolete MDM4 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070216 MDMX binding|MDM4 binding OBSOLETE. Interacting selectively and non-covalently with any isoform of the MDM4 protein, a negative regulator of p53. CHEBI:22569 anthocyanidin glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22569 UBERON:0003555 spinal cord pia mater biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003555 pia mater of neuraxis of spinal cord|pia mater of spinal cord|spinal cord pia mater of neuraxis A pia mater that is part of a spinal cord [Automatically generated definition]. GO:0070213 protein auto-ADP-ribosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070213 protein amino acid auto-ADP-ribosylation The ADP-ribosylation by a protein of one or more of its own amino acid residues, or residues on an identical protein. GO:0070214 CSK-GAP-A.p62 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070214 A protein complex that contains the protein-tyrosine kinase CSK and the GTPase-activating protein (GAP)-associated p62 (GAP-A.p62); may mediate translocation of proteins, including GAP and CSK, to membrane or cytoskeletal regions upon c-Src activation. UBERON:0003556 forebrain arachnoid mater biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003556 arachnoid of forebrain|forebrain arachnoid mater of neuraxis|arachnoid mater of neuraxis of forebrain|arachnoid mater of forebrain|forebrain arachnoid An arachnoid mater that is part of a forebrain [Automatically generated definition]. UBERON:0003553 diencephalon pia mater biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003553 mature diencephalon pia mater|mature diencephalon pia mater of neuraxis|pia mater of interbrain|pia mater of neuraxis of interbrain|between brain pia mater|between brain pia mater of neuraxis|pia mater of diencephalon|interbrain pia mater|pia mater of neuraxis of mature diencephalon|pia mater of neuraxis of diencephalon|interbrain pia mater of neuraxis|pia mater of mature diencephalon|diencephalon pia mater of neuraxis|pia mater of neuraxis of between brain|pia mater of between brain A pia mater that is part of a diencephalon [Automatically generated definition]. GO:0070211 Snt2C complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070211 A histone deacetylase complex that is part of the chromatin remodeling machinery. In Saccharomyces cerevisiae this complex contains Snt2p, Ecm5p and Rpd3p. GO:0070212 protein poly-ADP-ribosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070212 addition of poly-ADP-ribose to protein|protein poly(ADP-ribose) synthesis|protein amino acid poly-ADP-ribosylation|poly(ADP-ribose) addition to protein|protein poly(ADP-ribose) metabolism The transfer of multiple ADP-ribose residues from NAD to a protein amino acid, forming a poly(ADP-ribose) chain. UBERON:0003554 hindbrain pia mater biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003554 hindbrain pia mater of neuraxis|rhombencephalon pia mater|pia mater of neuraxis of hindbrain|pia mater of hindbrain A pia mater that is part of a hindbrain [Automatically generated definition]. UBERON:0003551 midbrain pia mater biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003551 mesencephalon pia mater|pia mater of midbrain|pia mater of neuraxis of midbrain|midbrain pia mater of neuraxis A pia mater that is part of a midbrain [Automatically generated definition]. UBERON:0003552 telencephalon pia mater biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003552 telencephalon pia mater of neuraxis|pia mater of neuraxis of telencephalon|pia mater of telencephalon A pia mater that is part of a telencephalon [Automatically generated definition]. GO:0070210 Rpd3L-Expanded complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070210 Clr6-LE complex A protein complex that contains a histone deacetylase and is part of the chromatin remodeling machinery. In Saccharomyces cerevisiae this complex contains the Rpd3p, Sin3p, Ume1p, Pho23p, Sap30p, Sds3p, Cti6p, Rxt2p, Rxt3p, Dep1p, Ume6p, Ash1p, Dot6p, Snt1, Sif2p, Set3p, Hos2p, Tos4p and Tod6p proteins. GO:0045262 plasma membrane proton-transporting ATP synthase complex, catalytic core F(1) biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045262 hydrogen-transporting ATP synthase, F1 sector|proton-transporting ATP synthase complex, catalytic core F(1) The catalytic sector of the plasma membrane hydrogen-transporting ATP synthase; it comprises the catalytic core and central stalk, and is peripherally associated with the plasma membrane when the entire ATP synthase is assembled. Examples of this component are found in Bacterial species. GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o) biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045263 proton-transporting ATP synthase complex, coupling factor F(0)|hydrogen-transporting ATP synthase complex, coupling factor F(o)|hydrogen-transporting ATP synthase, F0 sector|hydrogen-transporting ATP synthase, coupling factor CF(0) All non-F1 subunits of a hydrogen-transporting ATP synthase, including integral and peripheral membrane proteins. GO:0045260 plasma membrane proton-transporting ATP synthase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045260 hydrogen-translocating F-type ATPase complex|proton-transporting ATP synthase complex|plasma membrane hydrogen-translocating F-type ATPase complex|hydrogen-transporting ATP synthase A proton-transporting ATP synthase complex found in the plasma membrane. Examples of this component are found in Bacterial species. GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1) biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045261 hydrogen-transporting ATP synthase, F1 sector The sector of a hydrogen-transporting ATP synthase complex in which the catalytic activity resides; it comprises the catalytic core and central stalk, and is peripherally associated with a membrane, such as the plasma membrane or the mitochondrial inner membrane, when the entire ATP synthase is assembled. UBERON:0003539 left lung bronchiole biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003539 lobular bronchiole of left lung|bronchiole of left lung|left lung lobular bronchiole A bronchiole that is part of a left lung [Automatically generated definition]. GO:1901998 toxin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901998 The directed movement of a toxin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:1901999 homogentisate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901999 homogentisate metabolism The chemical reactions and pathways involving homogentisate. UBERON:0003538 right lung bronchiole biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003538 bronchiole of right lung|lobular bronchiole of right lung|right lung lobular bronchiole A bronchiole that is part of a right lung [Automatically generated definition]. OBO:GOCHE_76725 substance with EC 1.* (oxidoreductase) inhibitor role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_76725 GO:1901996 regulation of indoleacetic acid biosynthetic process via tryptophan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901996 regulation of indoleacetic acid formation via tryptophan|regulation of indoleacetic acid synthesis via tryptophan|regulation of indoleacetic acid anabolism via tryptophan|regulation of IAA biosynthetic process via tryptophan Any process that modulates the frequency, rate or extent of indoleacetic acid biosynthetic process via tryptophan. GO:1901997 negative regulation of indoleacetic acid biosynthetic process via tryptophan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901997 down-regulation of indoleacetic acid synthesis via tryptophan|negative regulation of indoleacetic acid synthesis via tryptophan|down-regulation of indoleacetic acid biosynthetic process via tryptophan|negative regulation of IAA biosynthetic process via tryptophan|down-regulation of IAA biosynthetic process via tryptophan|down-regulation of indoleacetic acid anabolism via tryptophan|negative regulation of indoleacetic acid anabolism via tryptophan|downregulation of indoleacetic acid formation via tryptophan|inhibition of indoleacetic acid biosynthetic process via tryptophan|downregulation of indoleacetic acid synthesis via tryptophan|down regulation of indoleacetic acid formation via tryptophan|down regulation of indoleacetic acid synthesis via tryptophan|downregulation of indoleacetic acid anabolism via tryptophan|inhibition of IAA biosynthetic process via tryptophan|down regulation of indoleacetic acid anabolism via tryptophan|inhibition of indoleacetic acid formation via tryptophan|inhibition of indoleacetic acid synthesis via tryptophan|down regulation of IAA biosynthetic process via tryptophan|down regulation of indoleacetic acid biosynthetic process via tryptophan|inhibition of indoleacetic acid anabolism via tryptophan|downregulation of IAA biosynthetic process via tryptophan|downregulation of indoleacetic acid biosynthetic process via tryptophan|down-regulation of indoleacetic acid formation via tryptophan|negative regulation of indoleacetic acid formation via tryptophan Any process that stops, prevents or reduces the frequency, rate or extent of indoleacetic acid biosynthetic process via tryptophan. GO:0045268 plasma membrane proton-transporting ATP synthase, catalytic core biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045268 proton-transporting ATP synthase, catalytic core|hydrogen-transporting ATP synthase, catalytic core The hexamer that possesses the catalytic activity of the plasma membrane hydrogen-transporting ATP synthase. Examples of this component are found in Bacterial species. GO:1901994 negative regulation of meiotic cell cycle phase transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901994 negative regulation of cell cycle transition|down-regulation of meiotic cell cycle phase transition|down-regulation of cell cycle transition|inhibition of meiotic cell cycle phase transition|inhibition of cell cycle transition|down regulation of cell cycle transition|down regulation of meiotic cell cycle phase transition|downregulation of cell cycle transition|downregulation of meiotic cell cycle phase transition Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle phase transition. GO:0045269 proton-transporting ATP synthase, central stalk biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045269 hydrogen-transporting ATP synthase, central stalk One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the membrane-associated Fo proteins; rotates within the catalytic core during catalysis. GO:1901995 positive regulation of meiotic cell cycle phase transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901995 positive regulation of cell cycle transition|activation of meiotic cell cycle phase transition|activation of cell cycle transition|up-regulation of cell cycle transition|up-regulation of meiotic cell cycle phase transition|upregulation of meiotic cell cycle phase transition|upregulation of cell cycle transition|up regulation of cell cycle transition|up regulation of meiotic cell cycle phase transition Any process that activates or increases the frequency, rate or extent of meiotic cell cycle phase transition. GO:1901992 positive regulation of mitotic cell cycle phase transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901992 up-regulation of mitotic cell cycle phase transition|upregulation of mitotic cell cycle phase transition|up regulation of mitotic cell cycle phase transition|activation of mitotic cell cycle phase transition Any process that activates or increases the frequency, rate or extent of mitotic cell cycle phase transition. GO:0045266 plasma membrane proton-transporting ATP synthase, stator stalk biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045266 proton-transporting ATP synthase, stator stalk|hydrogen-transporting ATP synthase, stator stalk One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the plasma membrane-associated F0 proteins; is thought to prevent futile rotation of the catalytic core. Examples of this component are found in Bacterial species. GO:0045267 proton-transporting ATP synthase, catalytic core biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045267 hydrogen-transporting ATP synthase, catalytic core The hexamer that possesses the catalytic activity of the mitochondrial hydrogen-transporting ATP synthase. GO:1901993 regulation of meiotic cell cycle phase transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901993 meiotic cell cycle control|regulation of cell cycle transition Any process that modulates the frequency, rate or extent of meiotic cell cycle phase transition. GO:0045264 plasma membrane proton-transporting ATP synthase complex, coupling factor F(o) biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045264 hydrogen-transporting ATP synthase, F0 sector|proton-transporting ATP synthase complex, coupling factor F(o)|proton-transporting ATP synthase complex, coupling factor F(0) All non-F1 subunits of the plasma membrane hydrogen-transporting ATP synthase, including integral and peripheral plasma membrane proteins. GO:1901990 regulation of mitotic cell cycle phase transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901990 mitotic cell cycle control Any process that modulates the frequency, rate or extent of mitotic cell cycle phase transition. GO:1901991 negative regulation of mitotic cell cycle phase transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901991 inhibition of mitotic cell cycle phase transition|down regulation of mitotic cell cycle phase transition|downregulation of mitotic cell cycle phase transition|down-regulation of mitotic cell cycle phase transition Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle phase transition. GO:0045265 proton-transporting ATP synthase, stator stalk biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045265 hydrogen-transporting ATP synthase, stator stalk One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the membrane-associated Fo proteins; is thought to prevent futile rotation of the catalytic core. GO:0060880 cell morphogenesis involved in semicircular canal fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060880 The change in form (cell shape and size) that occurs when a semicircular canal epithelial cell acquires the structural features that allow it to contribute to the process of semicircular canal fusion. GO:0060881 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0060881 GO:0060882 basement membrane disassembly involved in semicircular canal fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060882 basal lamina disassembly involved in semicircular canal fusion A process that results in the breakdown of the basement membrane that contributes to the process of semicircular canal fusion. GO:0060883 regulation of basement membrane disassembly involved in semicircular canal fusion by cell communication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060883 regulation of basal lamina disassembly involved in semicircular canal fusion by cell communication Any process that mediates interactions between a cell and its surroundings that modulates of the rate, frequency or extent of basement membrane disassembly involved in semicircular canal fusion. GO:0060884 clearance of cells from fusion plate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060884 The morphogenetic process in which cells are removed from the inner loop of a semicircular canal. GO:0070208 protein heterotrimerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070208 protein heterotrimer formation|protein heterotrimer biosynthesis|protein heterotrimer biosynthetic process|protein heterotrimer assembly The formation of a protein heterotrimer, a macromolecular structure consisting of three noncovalently associated subunits, of which not all are identical. GO:0060885 clearance of cells from fusion plate by apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060885 clearance of cells from fusion plate by apoptosis Any apoptotic process that contributes to the shaping of the semicircular canal by removing cells in the fusion plate, forming the loops of the canals. GO:0060886 clearance of cells from fusion plate by epithelial to mesenchymal transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060886 The process of epithelial to mesenchymal transition that contributes to the shaping of the semicircular canal by effectively removing epithelial cells from the fusion plate, forming the loops of the canals. GO:0070209 ASTRA complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070209 A protein complex that is part of the chromatin remodeling machinery; the acronym stands for ASsembly of Tel, Rvb and Atm-like kinase. In Saccharomyces cerevisiae this complex includes Rvb1p, Rvb2p, Tra1p, Tel2p, Asa1p, Ttilp and Tti2p. GO:0070206 protein trimerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070206 protein trimer biosynthetic process|protein trimer biosynthesis|protein trimer formation|protein trimer assembly The formation of a protein trimer, a macromolecular structure consisting of three noncovalently associated identical or nonidentical subunits. GO:0060887 limb epidermis development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060887 The process whose specific outcome is the progression of the epidermis of the limb over time, from its formation to the mature structure. The limb epidermis is the outer epithelial layer of the limb, it is a complex stratified squamous epithelium. GO:0060888 limb epidermis stratification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060888 The pattern specification process that results in the subdivision of the epidermis of the limb in space to define a volume in which specific patterns of basal cell, spinous cell and granular cells will differentiate giving rise to the layers of the limb epidermis. GO:0070207 protein homotrimerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070207 protein homotrimer formation|protein homotrimer biosynthesis|protein homotrimer biosynthetic process|protein homotrimer assembly The formation of a protein homotrimer, a macromolecular structure consisting of three noncovalently associated identical subunits. GO:0060889 limb basal epidermal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060889 The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal basal cell. A epidermal basal cell cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into more specialized cell of the limb epidermis. GO:0070204 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070204 EC:2.2.1.9|RHEA:25593|KEGG_REACTION:R08165|MetaCyc:2.5.1.64-RXN MenD|SEPHCHC synthase activity Catalysis of the reaction: 2-oxoglutarate + H(+) + isochorismate = 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate + CO(2). UBERON:0003546 distal convoluted tubule macula densa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003546 A macula densa that is part of a distal convoluted tubule [Automatically generated definition]. GO:0070205 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070205 MetaCyc:RXN-9310|RHEA:25597|KEGG_REACTION:R08166|EC:4.2.99.20 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase activity|SHCHC synthase activity|6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate synthase activity|MenH|YfbB Catalysis of the reaction: 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate = (1R,6R)-2-succinyl-6-hydroxycyclohexa-2,4-diene-1-carboxylate + pyruvate. UBERON:0003547 brain meninx biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003547 meninges of brain|meninx of brain|brain meninges A meninx that is part of a brain [Automatically generated definition]. UBERON:0003544 brain white matter biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003544 brain white substance|brain white matter of neuraxis|white matter of neuraxis of brain|white matter of brain|white substance of brain The regions of the brain that are largely or entirely composed of myelinated nerve cell axons and contain few or no neural cell bodies or dendrites. GO:0070202 regulation of establishment of protein localization to chromosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070202 regulation of establishment of protein localisation to chromosome Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location on a chromosome. GO:0070203 regulation of establishment of protein localization to telomere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070203 regulation of establishment of protein localisation to telomere Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location in the telomeric region of a chromosome. GO:0070200 establishment of protein localization to telomere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070200 establishment of protein localization to chromosome, telomeric region|establishment of protein localisation to telomere The directed movement of a protein to a specific location in the telomeric region of a chromosome. GO:0070201 regulation of establishment of protein localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070201 regulation of establishment of protein localisation Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location. UBERON:0003540 right lung terminal bronchiole biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003540 right lung bronchiolus terminalis|terminal bronchiole of right lung|bronchiolus terminalis of right lung A terminal bronchiole that is part of a right lung [Automatically generated definition]. UBERON:0003541 left lung terminal bronchiole biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003541 bronchiolus terminalis of left lung|left lung bronchiolus terminalis|terminal bronchiole of left lung A terminal bronchiole that is part of a left lung [Automatically generated definition]. GO:0045273 respiratory chain complex II biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0045273 electron transport complex II A part of the respiratory chain, containing the four polypeptide subunits of succinate dehydrogenase, flavin-adenine dinucleotide and iron-sulfur. Catalyzes the oxidation of succinate by ubiquinone. Connects the TCA cycle with the respiratory chain. GO:0045274 plasma membrane respiratory chain complex II biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045274 respiratory chain complex II A part of the respiratory chain located in the plasma membrane, containing the four polypeptide subunits of succinate dehydrogenase, flavin-adenine dinucleotide and iron-sulfur. Catalyzes the oxidation of succinate by ubiquinone. Connects the TCA cycle with the respiratory chain. Examples of this component are found in bacterial species. GO:0070230 positive regulation of lymphocyte apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070230 up regulation of lymphocyte apoptosis|positive regulation of lymphocyte apoptosis|upregulation of lymphocyte apoptosis|stimulation of lymphocyte apoptosis|up-regulation of lymphocyte apoptosis|activation of lymphocyte apoptosis Any process that activates or increases the frequency, rate or extent of lymphocyte death by apoptotic process. CHEBI:22542 androstane-3,17-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_22542 GO:0045271 respiratory chain complex I biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045271 NADH-Q oxidoreductase complex|NADH dehydrogenase (ubiquinone) complex|NADH dehydrogenase complex (ubiquinone)|electron transport complex I Respiratory chain complex I is an enzyme of the respiratory chain. It consists of several polypeptide chains and is L-shaped, with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix. The electrons of NADH enter the chain at this complex. GO:0045272 plasma membrane respiratory chain complex I biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045272 NADH dehydrogenase (ubiquinone) complex|respiratory chain complex I A subcomplex of the respiratory chain located in the plasma membrane. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone. Examples of this component are found in bacterial species. GO:0045270 plasma membrane proton-transporting ATP synthase, central stalk biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045270 hydrogen-transporting ATP synthase, central stalk|proton-transporting ATP synthase, central stalk One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the plasma membrane-associated Fo proteins; rotates within the catalytic core during catalysis. Examples of this component are found in Bacterial species. GO:0045279 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045279 GO:0045277 respiratory chain complex IV biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0045277 electron transport complex IV|cytochrome c oxidase complex A part of the respiratory chain, containing the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2). GO:0045278 plasma membrane respiratory chain complex IV biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045278 respiratory chain complex IV|cytochrome c oxidase complex A part of the respiratory chain located in the plasma membrane, containing the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2). Examples of this component are found in bacterial species. GO:0045275 respiratory chain complex III biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0045275 Wikipedia:Coenzyme_Q_-_cytochrome_c_reductase CoQH2-cytochrome c reductase complex|cytochrome bc1 complex|ubiquinol-cytochrome c oxidoreductase complex|coenzyme Q-cytochrome c reductase complex|coenzyme Q-cytochrome c oxidoreductase complex|electron transport complex III|ubiquinol-cytochrome-c reductase complex|cytochrome bc(1) complex|complex III A protein complex that transfers electrons from ubiquinol to cytochrome c and translocates two protons across a membrane. The complex contains a core structure of three catalytic subunits: cytochrome b, the Rieske iron sulfur protein (ISP), and cytochrome c1, which are arranged in an integral membrane-bound dimeric complex; additional subunits are present, and vary among different species. GO:0045276 plasma membrane respiratory chain complex III biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045276 respiratory chain complex III|plasma membrane coenzyme Q-cytochrome c oxidoreductase complex|ubiquinol-cytochrome-c reductase complex|plasma membrane ubiquinol-cytochrome-c reductase complex|ubiquinol-cytochrome c oxidoreductase complex|plasma membrane coenzyme Q-cytochrome c reductase complex|plasma membrane cytochrome bc1 complex A part of the respiratory chain located in the plasma membrane, containing about 10 polypeptide subunits including four redox centers: cytochrome b/b6, cytochrome c1 and an 2Fe-2S cluster. Catalyzes the oxidation of ubiquinol by oxidized cytochrome c1. Examples of this component are found in bacterial species. GO:0070239 regulation of activated T cell autonomous cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070239 regulation of activated T lymphocyte autonomous cell death|regulation of ACAD|regulation of activated T-cell autonomous cell death|regulation of activated T-lymphocyte autonomous cell death|regulation of activated cell autonomous cell death|regulation of activated T cell apoptosis Any process that modulates the occurrence or rate of activated T cell autonomous cell death. GO:0070237 positive regulation of activation-induced cell death of T cells biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070237 up regulation of activation-induced cell death of T cells|positive regulation of activation-induced cell death of T-lymphocytes|upregulation of activation-induced cell death of T cells|positive regulation of activation-induced cell death of T-cells|positive regulation of antigen-driven apoptosis|stimulation of activation-induced cell death of T cells|up-regulation of activation-induced cell death of T cells|activation of activation-induced cell death of T cells|positive regulation of activated T cell apoptosis|positive regulation of activation-induced cell death of T lymphocytes|positive regulation of AICD Any process that activates or increases the frequency, rate or extent of activation-induced cell death of T cells. GO:0070238 activated T cell autonomous cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070238 activated T-cell autonomous cell death|activated T-lymphocyte autonomous cell death|activated cell autonomous cell death|activated T cell apoptosis|activated T lymphocyte autonomous cell death|ACAD A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen via the accumulation of pro-apoptotic gene products and decrease in anti-apoptotic gene products. GO:0070235 regulation of activation-induced cell death of T cells biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070235 regulation of activation-induced cell death of T lymphocytes|regulation of AICD|regulation of activation-induced cell death of T-lymphocytes|regulation of activation-induced cell death of T-cells|regulation of antigen-driven apoptosis|regulation of activated T cell apoptosis Any process that modulates the occurrence or rate of activation-induced cell death of T cells. GO:0070236 negative regulation of activation-induced cell death of T cells biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070236 downregulation of activation-induced cell death of T cells|negative regulation of activation-induced cell death of T-lymphocytes|down regulation of activation-induced cell death of T cells|negative regulation of activation-induced cell death of T-cells|inhibition of activation-induced cell death of T cells|negative regulation of activated T cell apoptosis|negative regulation of activation-induced cell death of T lymphocytes|negative regulation of AICD|down-regulation of activation-induced cell death of T cells|negative regulation of antigen-driven apoptosis Any process that stops, prevents, or reduces the frequency, rate or extent of activation-induced cell death of T cells. GO:0070233 negative regulation of T cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070233 negative regulation of T cell apoptosis|down regulation of T cell apoptosis|inhibition of T cell apoptosis|negative regulation of T-cell apoptosis|negative regulation of T-lymphocyte apoptosis|down-regulation of T cell apoptosis|negative regulation of programmed cell death of T cells by apoptosis|negative regulation of T lymphocyte apoptosis|downregulation of T cell apoptosis Any process that stops, prevents, or reduces the frequency, rate or extent of T cell death by apoptotic process. GO:0070234 positive regulation of T cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070234 positive regulation of T cell apoptosis|upregulation of T cell apoptosis|stimulation of T cell apoptosis|positive regulation of T-cell apoptosis|up-regulation of T cell apoptosis|activation of T cell apoptosis|positive regulation of T-lymphocyte apoptosis|positive regulation of programmed cell death of T cells by apoptosis|up regulation of T cell apoptosis|positive regulation of T lymphocyte apoptosis Any process that activates or increases the frequency, rate or extent of T cell death by apoptotic process. GO:0070231 T cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070231 T-cell apoptosis|T-lymphocyte apoptosis|T lymphocyte apoptosis|programmed cell death of T cells by apoptosis|T cell apoptosis Any apoptotic process in a T cell, a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex. GO:0070232 regulation of T cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070232 regulation of T lymphocyte apoptosis|regulation of T cell apoptosis|regulation of programmed cell death of T cells by apoptosis|regulation of T-cell apoptosis|regulation of T-lymphocyte apoptosis Any process that modulates the occurrence or rate of T cell death by apoptotic process. GO:0045284 plasma membrane fumarate reductase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045284 fumarate reductase complex A membrane-bound flavoenzyme complex consisting of four subunits, A, B, C, and D. A and B comprise the membrane-extrinsic catalytic domain and C (InterPro:IPR003510; InterPro:IPR00224) and D (InterPro:IPR003418) link the catalytic centers to the electron-transport chain. In some species, the complex has only three subunits, and in these cases, there is only one membrane anchor instead of two. This family consists of the 13 kDa hydrophobic subunit D. This component may be required to anchor the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. Fumarate reductase couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, in a reaction opposite to that catalyzed by the related complex II of the respiratory chain (succinate dehydrogenase-(ubiquinone)). Examples of this component are found in bacterial species. GO:0045285 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045285 GO:0045282 plasma membrane succinate dehydrogenase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045282 succinate dehydrogenase complex A multimeric complex which consists of flavoprotein (subunit A ; InterPro:IPR003952), iron-sulfur protein (subunit B) and membrane-bound cytochrome b560 (subunit C; InterPro:IPR000701). In some Archaea, the membrane-bound subunits (C or C and D) do not necessarily contain heme. Membrane-bound subunits can bind/react with quinones. Examples of this component are found in Bacterial species. GO:0045283 fumarate reductase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045283 A membrane-bound flavoenzyme complex consisting of four subunits, A, B, C, and D. A and B comprise the membrane-extrinsic catalytic domain and C (InterPro:IPR003510; InterPro:IPR004224) and D (InterPro:IPR003418) link the catalytic centers to the electron-transport chain. This family consists of the 13 kDa hydrophobic subunit D. This component may be required to anchor the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. Fumarate reductase couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, in a reaction opposite to that catalyzed by the related complex II of the respiratory chain (succinate dehydrogenase-(ubiquinone)). GO:0045280 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045280 GO:0045281 succinate dehydrogenase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045281 A multimeric complex which consists of flavoprotein (subunit A ; InterPro:IPR003952), iron-sulfur protein (subunit B) and membrane-bound cytochrome b560 (subunit C; InterPro:IPR000701). In some Archaea, the membrane-bound subunits (C or C and D) do not necessarily contain heme. Membrane-bound subunits can bind or react with quinones. CHEBI:22557 anhydrohexose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22557 CHEBI:46502 tungstate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46502 GO:0045288 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045288 GO:0045289 luciferin monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045289 luciferase activity|luciferase monooxygenase activity Catalysis of the generalized reaction: luciferin + O2 = oxidized luciferin + CO2 + light. There may be additional substrates and reactants involved in the reaction. The reaction results in light emission as luciferin returns to the ground state after enzymatic oxidation. GO:0045286 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045286 GO:0045287 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045287 GO:0070228 regulation of lymphocyte apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070228 regulation of lymphocyte apoptosis Any process that modulates the occurrence or rate of lymphocyte death by apoptotic process. GO:0070229 negative regulation of lymphocyte apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070229 downregulation of lymphocyte apoptosis|negative regulation of lymphocyte apoptosis|down regulation of lymphocyte apoptosis|inhibition of lymphocyte apoptosis|down-regulation of lymphocyte apoptosis Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte death by apoptotic process. GO:0070226 sulfur:ferric ion oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070226 MetaCyc:SULFFEOXIDO-RXN hydrogen sulfide:ferric ion oxidoreductase Catalysis of the reaction: a perthiol + 4 Fe3+ + 3 H2O = sulfite + a thiol + 4 Fe2+ + 8 H+. GO:0070227 lymphocyte apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070227 lymphocyte apoptosis Any apoptotic process in a lymphocyte, a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin. GO:0070224 sulfide:quinone oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070224 RHEA:30239|MetaCyc:R17-RXN|Reactome:R-HSA-1614665 sulphide:quinone oxidoreductase activity|sulfide-quinone reductase activity Catalysis of the reaction: hydrogen sulfide + a quinone = S0 + a hydroquinone. CHEBI:22558 anhydro sugar biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22558 GO:0070225 sulfide dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070225 MetaCyc:RXN-8156|RHEA:30223|EC:1.8.2.- sulphide dehydrogenase activity|flavocytochrome c sulfide dehydrogenase activity Catalysis of the reaction: hydrogen sulfide + oxidized cytochrome c = S0 + reduced cytochrome c. GO:0070222 sulfide oxidation, using sulfide dehydrogenase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070222 MetaCyc:PWY-5274 sulphide oxidation, using sulfide dehydrogenase A sulfide oxidation process that proceeds via the reaction catalyzed by sulfide dehydrogenase. GO:0070223 sulfide oxidation, using sulfur dioxygenase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070223 MetaCyc:PWY-5285 sulphide oxidation, using sulfur dioxygenase A sulfide oxidation process that proceeds via the reaction catalyzed by sulfur dioxygenase. GO:0070220 aerobic sulfur oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070220 MetaCyc:SULFUROX-PWY aerobic sulphur oxidation A sulfur oxidation process that proceeds via the reaction catalyzed by sulfur dioxygenase, and requires the presence of oxygen. GO:0070221 sulfide oxidation, using sulfide:quinone oxidoreductase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070221 MetaCyc:P222-PWY sulphide oxidation, using sulfide:quinone oxidoreductase|sulfide oxidation, using sulfide-quinone reductase A sulfide oxidation process that proceeds via the reaction catalyzed by sulfide:quinone oxidoreductase. GO:0045295 gamma-catenin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045295 plakoglobin binding Interacting selectively and non-covalently with the gamma subunit of the catenin complex. GO:0070251 pristanate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070251 RHEA:47264|Reactome:R-HSA-389632 pristanoyl-CoA ligase activity|pristanate:CoA ligase (AMP-forming) Catalysis of the reaction: ATP + pristanate + CoA = AMP + diphosphate + pristanoyl-CoA. GO:0070252 actin-mediated cell contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070252 The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of all or part of the cell body. GO:0045296 cadherin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045296 Interacting selectively and non-covalently with cadherin, a type I membrane protein involved in cell adhesion. GO:0045293 mRNA editing complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0045293 editosome A protein complex that posttranscriptionally catalyzes insertion, deletion or substitution of nucleotides at multiple sites within nascent mRNA transcripts to produce mature mRNAs in eukaryotes. GO:0045294 alpha-catenin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045294 Interacting selectively and non-covalently with the alpha subunit of the catenin complex. GO:0070250 mating projection membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070250 shmoo membrane The portion of the plasma membrane surrounding a mating projection, the projection formed by unicellular fungi in response to mating pheromone. GO:0045291 mRNA trans splicing, SL addition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045291 nuclear mRNA trans splicing, spliced leader addition|nuclear mRNA trans splicing, SL addition The joining together of two independently transcribed RNAs, where the one that provides the 5' portion of the final mRNA is from a splice leader RNA (SL-RNA). The SL-RNA, or mini-exon donor sequence, is added to the 5'-end of the acceptor RNA molecule which provides the mRNA body. GO:0045292 mRNA cis splicing, via spliceosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045292 splicing|nuclear mRNA cis splicing, via spliceosome|nuclear mRNA cis splicing, via U2-type spliceosome The joining together, after removal of an intervening sequence composed of one or more introns, of two segments of the same RNA molecule via spliceosomal catalysis to produce an mRNA composed only of exon sequences that all came from the same primary transcript. GO:0045290 D-arabinose 1-dehydrogenase [NAD(P)+] activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045290 MetaCyc:1.1.1.117-RXN|EC:1.1.1.117 D-arabinose:NAD(P)+ 1-oxidoreductase activity Catalysis of the reaction: D-arabinose + NAD(P)+ = D-arabinono-1,4-lactone + NAD(P)H + H+. GO:0045299 otolith mineralization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045299 The precipitation of specific crystal forms of calcium carbonate with extracellular matrix proteins in the otolith organs of the vertebrate inner ear. CHEBI:356416 5-ammoniolevulinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_356416 GO:0045297 obsolete post-mating behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045297 post-mating behaviour OBSOLETE. The specific behavior of an organism following mating. GO:0045298 tubulin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045298 A heterodimer of tubulins alpha and beta that constitutes the protomer for microtubule assembly. UBERON:0003593 thoracic cavity connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003593 textus connectivus of cavity of thorax|connective tissue of chest cavity|cavity of thorax textus connectivus|portion of connective tissue of thoracic cavity|chest cavity portion of connective tissue|portion of connective tissue of cavity of chest|portion of connective tissue of pectoral cavity|connective tissue of cavity of thorax|chest cavity connective tissue|chest cavity textus connectivus|pectoral cavity portion of connective tissue|portion of connective tissue of chest cavity|cavity of chest portion of connective tissue|thoracic cavity portion of connective tissue|cavity of thorax connective tissue|connective tissue of thoracic cavity|connective tissue of pectoral cavity|connective tissue of cavity of chest|cavity of chest textus connectivus|pectoral cavity textus connectivus|textus connectivus of chest cavity|portion of connective tissue of cavity of thorax|thoracic cavity textus connectivus|textus connectivus of thoracic cavity|cavity of thorax portion of connective tissue|pectoral cavity connective tissue|cavity of chest connective tissue|textus connectivus of cavity of chest|textus connectivus of pectoral cavity A portion of connective tissue that is part of a thoracic cavity [Automatically generated definition]. UBERON:0003594 pelvis connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003594 pelvis textus connectivus|textus connectivus of pelvis|connective tissue of pelvis|pelvis portion of connective tissue|portion of connective tissue of pelvis A portion of connective tissue that is part of a pelvis [Automatically generated definition]. UBERON:0003591 lobar bronchus connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003591 connective tissue of lobar bronchus|connective tissue of secondary bronchus A portion of connective tissue that is part of a lobar bronchus [Automatically generated definition]. UBERON:0003592 bronchus connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003592 connective tissue of bronchi|bronchus portion of connective tissue|connective tissue of bronchial trunk|bronchial trunk portion of connective tissue|bronchial connective tissue|connective tissue of bronchus|bronchi portion of connective tissue|bronchus textus connectivus|textus connectivus of bronchi|bronchial trunk textus connectivus|bronchi connective tissue|bronchial trunk connective tissue|bronchi textus connectivus|textus connectivus of bronchial trunk|portion of connective tissue of bronchi|portion of connective tissue of bronchial trunk|bronchial mesenchyme|portion of connective tissue of bronchus|textus connectivus of bronchus A portion of connective tissue that is part of a bronchus [Automatically generated definition]. CHEBI:22527 aminopurine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22527 GO:0070259 tyrosyl-DNA phosphodiesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070259 Catalysis of the hydrolysis of phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between a DNA topoisomerase and DNA. UBERON:0003599 tail connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003599 textus connectivus of tail|tail portion of connective tissue|post-vent region portion of connective tissue|connective tissue of post-vent region|tail textus connectivus|connective tissue of tail|post-vent region textus connectivus|post-vent region connective tissue|portion of connective tissue of post-vent region|portion of connective tissue of tail|textus connectivus of post-vent region A portion of connective tissue that is part of a tail [Automatically generated definition]. GO:0070257 positive regulation of mucus secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070257 positive regulation of mucus production Any process that activates or increases the frequency, rate or extent of the regulated release of mucus from a cell or a tissue. GO:0070258 inner membrane pellicle complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070258 inner membrane complex A membrane structure formed of two closely aligned lipid bilayers that lie beneath the plasma membrane and form part of the pellicle surrounding an apicomplexan parasite cell. UBERON:0003597 manual digit connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003597 hand digit connective tissue|hand digit connective tissue|connective tissue of finger|connective tissue of digit of hand|connective tissue of digitus manus|connective tissue of hand digit|fore limb digit connective tissue A portion of connective tissue that is part of a finger [Automatically generated definition]. GO:0070255 regulation of mucus secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070255 regulation of mucus production Any process that modulates the frequency, rate or extent of the regulated release of mucus from a cell or a tissue. UBERON:0003598 manus connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003598 connective tissue of hand|connective tissue of terminal segment of free upper limb|hand connective tissue A portion of connective tissue that is part of a hand [Automatically generated definition]. GO:0070256 negative regulation of mucus secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070256 negative regulation of mucus production Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of mucus from a cell or a tissue. CHEBI:22529 amino sugar phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22529 UBERON:0003595 pes connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003595 textus connectivus of pes|connective tissue of foot|connective tissue of terminal segment of free lower limb|foot connective tissue A portion of connective tissue that is part of a foot [Automatically generated definition]. GO:0070253 somatostatin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070253 The regulated release of somatostatin from secretory granules in the D cells of the pancreas. UBERON:0003596 ankle connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003596 connective tissue of ankle|tarsal region connective tissue A portion of connective tissue that is part of an ankle [Automatically generated definition]. GO:0070254 mucus secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070254 mucus production The regulated release of mucus by the mucosa. Mucus is a viscous slimy secretion consisting of mucins and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes. The mucosa, or mucous membrane, is the membrane covered with epithelium that lines the tubular organs of the body. Mucins are carbohydrate-rich glycoproteins that have a lubricating and protective function. GO:0070240 negative regulation of activated T cell autonomous cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070240 negative regulation of activated T lymphocyte autonomous cell death|negative regulation of ACAD|downregulation of activated T cell autonomous cell death|down regulation of activated T cell autonomous cell death|inhibition of activated T cell autonomous cell death|negative regulation of activated T-cell autonomous cell death|negative regulation of activated cell autonomous cell death|negative regulation of activated T-lymphocyte autonomous cell death|negative regulation of activated T cell apoptosis|down-regulation of activated T cell autonomous cell death Any process that stops, prevents, or reduces the frequency, rate or extent of activated T cell autonomous cell death. GO:0070241 positive regulation of activated T cell autonomous cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070241 positive regulation of activated T cell apoptosis|up regulation of activated T cell autonomous cell death|positive regulation of activated T lymphocyte autonomous cell death|positive regulation of ACAD|upregulation of activated T cell autonomous cell death|stimulation of activated T cell autonomous cell death|positive regulation of activated T-cell autonomous cell death|activation of activated T cell autonomous cell death|up-regulation of activated T cell autonomous cell death|positive regulation of activated cell autonomous cell death|positive regulation of activated T-lymphocyte autonomous cell death Any process that activates or increases the frequency, rate or extent of activated T cell autonomous cell death. CHEBI:22532 aminouracil biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22532 UBERON:0003582 nasopharynx connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003582 connective tissue of nasal part of pharynx|connective tissue of rhinopharynx|textus connectivus of nasopharynx|rhinopharynx portion of connective tissue|nasal part of pharynx connective tissue|textus connectivus of nasal part of pharynx|nasal part of pharynx portion of connective tissue|rhinopharynx connective tissue|nasopharynx portion of connective tissue|portion of connective tissue of nasopharynx|rhinopharynx textus connectivus|portion of connective tissue of nasal part of pharynx|nasal part of pharynx textus connectivus|portion of connective tissue of rhinopharynx|nasopharynx textus connectivus|textus connectivus of rhinopharynx|connective tissue of nasopharynx A portion of connective tissue that is part of a nasopharynx [Automatically generated definition]. UBERON:0003583 larynx connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003583 connective tissue of larynx|larynx portion of connective tissue|larynx textus connectivus|portion of connective tissue of larynx|textus connectivus of larynx|laryngeal connective tissue A portion of connective tissue that is part of a larynx [Automatically generated definition]. UBERON:0003580 lower respiratory tract connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003580 lower respiratory tract portion of connective tissue|lower respiratory tract textus connectivus|connective tissue of lower respiratory tract|textus connectivus of lower respiratory tract|portion of connective tissue of lower respiratory tract A portion of connective tissue that is part of a lower respiratory tract [Automatically generated definition]. UBERON:0003581 eyelid connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003581 connective tissue of blepharon|blepharon connective tissue|connective tissue of eyelid A portion of connective tissue that is part of a eyelid [Automatically generated definition]. NCBITaxon:9347 Eutheria organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_9347 placental mammals|Placentalia|placentals|eutherian mammals|placentals GO:0070248 negative regulation of natural killer cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070248 down regulation of natural killer cell apoptosis|downregulation of natural killer cell apoptosis|negative regulation of NK cell apoptosis|down-regulation of natural killer cell apoptosis|inhibition of natural killer cell apoptosis|negative regulation of natural killer cell apoptosis Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell death by apoptotic process. SO:0002308 DNA_loop_anchor biolink:SequenceFeature go-plus http://purl.obolibrary.org/obo/SO_0002308 DNA loop anchor The ends of a DNA loop where the two strands of DNA are held in close proximity. During interphase the anchors of DNA loops are CTCF binding sites. SO:0002309 core_promoter_element biolink:SequenceFeature go-plus http://purl.obolibrary.org/obo/SO_0002309 core promoter element An element that always exists within the promoter region of a gene. When multiple transcripts exist for a gene, the separate transcripts may have separate core_promoter_elements. GO:0070249 positive regulation of natural killer cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070249 upregulation of natural killer cell apoptosis|positive regulation of NK cell apoptosis|up regulation of natural killer cell apoptosis|activation of natural killer cell apoptosis|stimulation of natural killer cell apoptosis|up-regulation of natural killer cell apoptosis|positive regulation of natural killer cell apoptosis Any process that activates or increases the frequency, rate or extent of natural killer cell death by apoptotic process. UBERON:0003588 forelimb connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003588 connective tissue of superior member|wing connective tissue|connective tissue of upper extremity|connective tissue of anteriormost limb|connective tissue of fore limb|connective tissue of forelimb A portion of connective tissue that is part of a forelimb [Automatically generated definition]. GO:0070246 natural killer cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070246 NK cell apoptosis|natural killer cell apoptosis Any apoptotic process in a natural killer cell, a lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation. UBERON:0003589 hindlimb connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003589 connective tissue of hindlimb|connective tissue of inferior member|connective tissue of hind limb|connective tissue of lower extremity|hind limb connective tissue A portion of connective tissue that is part of a hindlimb [Automatically generated definition]. GO:0070247 regulation of natural killer cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070247 regulation of natural killer cell apoptosis|regulation of NK cell apoptosis Any process that modulates the occurrence or rate of natural killer cell death by apoptotic process. SO:0002307 DNA_loop biolink:SequenceFeature go-plus http://purl.obolibrary.org/obo/SO_0002307 DNA loop A region of DNA between two positions that are held in close proximity. UBERON:0003586 trunk connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003586 textus connectivus of trunk|torso connective tissue|textus connectivus of torso|portion of connective tissue of trunk|portion of connective tissue of torso|connective tissue of trunk|torso portion of connective tissue|trunk portion of connective tissue|connective tissue of torso|torso textus connectivus|trunk textus connectivus A portion of connective tissue that is part of a trunk [Automatically generated definition]. SO:0002304 topologically_associated_domain biolink:SequenceFeature go-plus http://purl.obolibrary.org/obo/SO_0002304 TAD|topologically associated domain An instance of a self-interacting DNA region flanked by left and right TAD boundaries. GO:0070244 negative regulation of thymocyte apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070244 down-regulation of thymocyte apoptosis|inhibition of thymocyte apoptosis|negative regulation of thymocyte apoptosis|negative regulation of immature T cell apoptosis|down regulation of thymocyte apoptosis|downregulation of thymocyte apoptosis Any process that stops, prevents, or reduces the frequency, rate or extent of thymocyte death by apoptotic process. GO:0070245 positive regulation of thymocyte apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070245 positive regulation of thymocyte apoptosis|up-regulation of thymocyte apoptosis|positive regulation of immature T cell apoptosis|upregulation of thymocyte apoptosis|up regulation of thymocyte apoptosis|activation of thymocyte apoptosis|stimulation of thymocyte apoptosis Any process that activates or increases the frequency, rate or extent of thymocyte death by apoptotic process. SO:0002305 topologically_associated_domain_boundary biolink:SequenceFeature go-plus http://purl.obolibrary.org/obo/SO_0002305 TAD boundary|TAD_boundary|topologically associated domain boundary A DNA region enriched in DNA loop anchors and across which DNA loops occur less often than expected by chance. UBERON:0003587 limb connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003587 portion of connective tissue of limb|textus connectivus of limb|limb portion of connective tissue|connective tissue of limb|limb textus connectivus A portion of connective tissue that is part of a limb [Automatically generated definition]. GO:0070242 thymocyte apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070242 thymocyte apoptosis|immature T cell apoptosis Any apoptotic process in a thymocyte, an immature T cell located in the thymus. UBERON:0003584 mammary gland connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003584 lactiferous gland connective tissue|connective tissue of mammary gland|lactiferous gland stroma|mammary stroma|connective tissue of lobe of breast|lactiferous gland portion of connective tissue|connective tissue of lobe of mammary gland|stroma of lactiferous gland|connective tissue of lactiferous gland|mammary gland stroma The fibrous supportive tissue of the mammary gland. GO:0070243 regulation of thymocyte apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070243 regulation of immature T cell apoptosis|regulation of thymocyte apoptosis Any process that modulates the occurrence or rate of thymocyte death by apoptotic process. UBERON:0003585 dermis connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003585 connective tissue of dermis|dermis portion of connective tissue|dermis textus connectivus|portion of connective tissue of dermis|textus connectivus of dermis A portion of connective tissue that is part of a dermis [Automatically generated definition]. UBERON:0003609 aorta elastic tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003609 elastic tissue of trunk of aortic tree|textus connectivus elasticus of adult aorta|elastic connective tissue of trunk of aortic tree|dorsal aorta textus connectivus elasticus|dorsal aorta elastic tissue|adult aorta textus connectivus elasticus|aorta elastic laminae|adult aorta elastic tissue|textus connectivus elasticus of dorsal aorta|trunk of aortic tree elastic connective tissue|aorta textus connectivus elasticus|elastic tissue of dorsal aorta|aorta elastic lamina|aorta elastic connective tissue|elastic connective tissue of dorsal aorta|elastic connective tissue of aorta|trunk of aortic tree textus connectivus elasticus|trunk of aortic tree elastic tissue|elastic tissue of aorta|adult aorta elastic connective tissue|elastic connective tissue of adult aorta|textus connectivus elasticus of aorta|dorsal aorta elastic connective tissue|textus connectivus elasticus of trunk of aortic tree|elastic tissue of adult aorta The dense connective tissue which contains predominantly elastic fibers and is found in the tunica media of the aorta wall. CHEBI:71476 EC 2.3.1.85 (fatty acid synthase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71476 UBERON:0003607 forelimb long bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003607 long bone of upper extremity|long bone of anteriormost limb|long bone of fore limb|upper extremity long bone|long bone of forelimb|anteriormost limb long bone|fore limb long bone|long bone of superior member|wing long bone|superior member long bone A long bone that is part of a forelimb [Automatically generated definition]. CHEBI:71477 guanosine 3'-diphosphate 5'-triphosphate(7-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71477 SO:0002221 eukaryotic_promoter biolink:SequenceFeature go-plus http://purl.obolibrary.org/obo/SO_0002221 Eukaryotic promoter A regulatory_region including the Transcription Start Site (TSS) of a gene and serving as a platform for Pre-Initiation Complex (PIC) assembly, enabling transcription of a gene under certain conditions. UBERON:0003608 hindlimb long bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003608 long bone of inferior member|long bone of hind limb|long bone of lower extremity|inferior member long bone|hind limb long bone|lower extremity long bone|long bone of hindlimb A long bone that is part of a hindlimb [Automatically generated definition]. SO:0002222 prokaryotic_promoter biolink:SequenceFeature go-plus http://purl.obolibrary.org/obo/SO_0002222 Prokaryotic promoter A regulatory_region essential for the specific initiation of transcription at a defined location in a DNA molecule, although this location might not be one single base. It is recognized by a specific RNA polymerase(RNAP)-holoenzyme, and this recognition is not necessarily autonomous. UBERON:0003605 eye skin gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003605 skin glands set of vertebrate eye|skin glands of vertebrate eye|skin glands of camera-type eye|vertebrate eye skin glands set|skin glands set of camera-type eye|vertebrate eye skin glands|camera-type eye skin gland|skin gland of camera-type eye|camera-type eye skin glands set|camera-type eye skin glands|skin gland of vertebrate eye|vertebrate eye skin gland A skin gland that is part of a camera-type eye [Automatically generated definition]. UBERON:0003606 limb long bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003606 long bone of limb A long bone that is part of a limb [Automatically generated definition]. UBERON:0003603 lower respiratory tract cartilage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003603 cartilage of lower respiratory tract A cartilage that is part of a lower respiratory tract [Automatically generated definition]. UBERON:0003604 trachea cartilage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003604 cartilago trachealis|cartilage of the trachea|cartilaginous ring of trachea|trachea ring|tracheal cartilage|tracheal ring|cartilaginous trachea cartilage|cartilage of trachea|cartilage of windpipe|ring of the trachea|cartilagines tracheales|windpipe cartilage the ring-shaped cartilaginous structures that support the trachea UBERON:0003613 cardiovascular system elastic tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003613 textus connectivus elasticus of cardiovascular system|circulatory system textus connectivus elasticus|textus connectivus elasticus of circulatory system|circulatory system elastic tissue|elastic tissue of circulatory system|elastic connective tissue of circulatory system|circulatory system elastic connective tissue|cardiovascular system elastic connective tissue|elastic connective tissue of cardiovascular system|elastic tissue of cardiovascular system|cardiovascular system textus connectivus elasticus An elastic tissue that is part of a circulatory system [Automatically generated definition]. UBERON:0003610 heart elastic tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003610 cardiac elastic tissue|heart elastic connective tissue|elastic connective tissue of heart|heart textus connectivus elasticus|elastic tissue of heart|textus connectivus elasticus of heart The type of heart connective tissue found in the endocardial layer that consists mainly of elastic fibers. UBERON:0003611 respiratory system elastic tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003611 elastic connective tissue of respiratory system|apparatus respiratorius textus connectivus elasticus|apparatus respiratorius elastic tissue|respiratory system elastic connective tissue|respiratory system textus connectivus elasticus|apparatus respiratorius elastic connective tissue|elastic connective tissue of apparatus respiratorius|elastic tissue of apparatus respiratorius|textus connectivus elasticus of respiratory system|textus connectivus elasticus of apparatus respiratorius|elastic tissue of respiratory system An elastic tissue that is part of a respiratory system [Automatically generated definition]. CHEBI:71487 chanoclavine-I aldehyde(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71487 CHEBI:71488 all-cis-8,11,14,17-icosatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71488 CHEBI:71489 (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71489 GO:0045402 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045402 GO:0045403 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045403 GO:0045400 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045400 GO:0045401 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045401 PR:000007141 erythropoietin biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000007141 EPO|epoetin A protein that is a translation product of the human EPO gene or a 1:1 ortholog thereof. PR:000007142 erythropoietin receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000007142 EPOR|EPO-R A protein that is a translation product of the human EPOR gene or a 1:1 ortholog thereof. GO:0045408 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045408 GO:0045409 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045409 GO:0045406 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045406 GO:0045407 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045407 GO:0045404 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045404 GO:0045405 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045405 UBERON:0003601 neck cartilage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003601 neck (volume) cartilage|cartilage of neck|cartilage of neck (volume) A cartilage that is part of a neck [Automatically generated definition]. CHEBI:71481 (8Z,11Z,14Z)-3-oxoicosa-8,11,14-trienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71481 PO:0007033 whole plant development stage biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0007033 cereal plant growth stage ontology (GRO:0007199) (related)|sorghum growth stage (GRO:0007124) (related)|rice growth stage (GRO:0007040) (related)|maize growth stage (GRO:0007002) (related)|wheat, barley and oat growth stage (GRO:0007156) (related)|plant growth stages in Arabidopsis (TAIR:0000021) (related)|Solanaceae whole plant growth stages (SGN:0000001) (related) A plant structure development stage (PO:0009012) that has as primary participant a whole plant (PO:0000003). GO:1901905 response to tamsulosin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901905 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tamsulosin stimulus. GO:1901906 diadenosine pentaphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901906 diadenosine pentaphosphate metabolism|diadenosyl pentaphosphate metabolism|diadenosyl pentaphosphate metabolic process The chemical reactions and pathways involving diadenosine pentaphosphate. CHEBI:71498 1-O-(4-coumaroyl)-beta-D-glucose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71498 GO:1901903 tyrocidine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901903 tyrocidine breakdown|tyrocidine catabolism|tyrocidine degradation The chemical reactions and pathways resulting in the breakdown of tyrocidine. CHEBI:71499 cyanidin 3-O-{6-O-[6-O-(4-coumaroyl)-beta-D-glucosyl]-2-O-beta-D-xylosyl-beta-D-galactoside} biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71499 GO:1901904 tyrocidine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901904 tyrocidine biosynthesis|tyrocidine anabolism|tyrocidine synthesis|tyrocidine formation The chemical reactions and pathways resulting in the formation of tyrocidine. GO:1901901 regulation of protein localization to cell division site involved in cytokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901901 regulation of protein localisation to cell division site involved in cytokinesis Any regulation of protein localization to cell division site that is involved in cytokinesis. GO:1901902 tyrocidine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901902 tyrocidine metabolism The chemical reactions and pathways involving tyrocidine. GO:1901900 regulation of protein localization to cell division site biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901900 regulation of protein localisation to cell division site Any process that modulates the frequency, rate or extent of protein localization to cell division site. GO:0045413 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045413 GO:0045414 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045414 GO:0045411 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045411 GO:0045412 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045412 GO:0045410 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045410 GO:0045419 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045419 CHEBI:141748 N-acetyl-beta-D-galactosaminyl-(1->4)-[N-acetyl-alpha-neuraminosyl-(2->8)-N-acetyl-alpha-neuraminosyl-(2->8)-N-acetyl-alpha-neuraminosyl-(2->3)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_141748 GO:0045417 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045417 GO:0045418 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045418 CHEBI:141743 beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)-[N-acetyl-alpha-neuraminosyl-(2->8)-N-acetyl-alpha-neuraminosyl-(2->8)-N-acetyl-alpha-neuraminosyl-(2->3)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_141743 GO:0045415 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045415 GO:0045416 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045416 CHEBI:71490 precorrin-7(6-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71490 CHEBI:71491 (8Z,11Z,14Z,17Z)-3-oxoicosatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71491 CHEBI:71492 (2R)-3-(3,4-dihydroxyphenyl)lactate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71492 GO:1901909 diadenosine hexaphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901909 diadenosine hexaphosphate catabolism|diadenosyl hexaphosphate degradation|diadenosyl hexaphosphate breakdown|diadenosyl hexaphosphate catabolic process|diadenosyl hexaphosphate catabolism The chemical reactions and pathways resulting in the breakdown of diadenosine hexaphosphate. CHEBI:71493 (R)-rosmarinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71493 CHEBI:71494 cis-trans-nepetalactol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71494 GO:1901907 diadenosine pentaphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901907 diadenosine pentaphosphate catabolism|diadenosyl pentaphosphate catabolism|diadenosyl pentaphosphate degradation|diadenosyl pentaphosphate breakdown|diadenosyl pentaphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of diadenosine pentaphosphate. GO:1901908 diadenosine hexaphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901908 diadenosyl hexaphosphate metabolism|diadenosine hexaphosphate metabolism|diadenosyl hexaphosphate metabolic process The chemical reactions and pathways involving diadenosine hexaphosphate. GO:1901916 obsolete protein kinase activity involved in regulation of protein localization to cell division site involved in cytokinesis biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1901916 protein kinase activity involved in regulation of protein localisation to cell division site involved in cytokinesis|protamine kinase activity involved in regulation of protein localisation to cell division site involved in cytokinesis|protamine kinase activity involved in regulation of protein localization to cell division site involved in cytokinesis OBSOLETE. Any protein kinase activity that is involved in regulation of protein localization to cell division site involved in cytokinesis. SO:0002234 pumilio_response_element biolink:SequenceFeature go-plus http://purl.obolibrary.org/obo/SO_0002234 pumilio response element|PRE binding RNA A cis-acting element involved in RNA stability found in the 3' UTR of some RNA (consensus UGUAAAUA). GO:1901917 regulation of exoribonuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901917 Any process that modulates the frequency, rate or extent of exoribonuclease activity. GO:1901914 negative regulation of capsule organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901914 down regulation of capsule organization|inhibition of capsule organization|inhibition of capsule organization and biogenesis|down regulation of capsule organization and biogenesis|down-regulation of capsule organisation|negative regulation of capsule organisation|downregulation of capsule organization and biogenesis|down-regulation of capsule organization|downregulation of capsule organisation|negative regulation of capsule organization and biogenesis|down-regulation of capsule organization and biogenesis|down regulation of capsule organisation|inhibition of capsule organisation|downregulation of capsule organization Any process that stops, prevents or reduces the frequency, rate or extent of capsule organization. GO:1901915 positive regulation of capsule organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901915 upregulation of capsule organization|up-regulation of capsule organisation|activation of capsule organisation|upregulation of capsule organization and biogenesis|up-regulation of capsule organization|activation of capsule organization|positive regulation of capsule organisation|up regulation of capsule organization and biogenesis|up regulation of capsule organisation|positive regulation of capsule organization and biogenesis|activation of capsule organization and biogenesis|up regulation of capsule organization|upregulation of capsule organisation|up-regulation of capsule organization and biogenesis Any process that activates or increases the frequency, rate or extent of capsule organization. GO:1901912 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1901912 GO:1901913 regulation of capsule organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901913 regulation of capsule organization and biogenesis|regulation of capsule organisation Any process that modulates the frequency, rate or extent of capsule organization. GO:1901910 adenosine 5'-(hexahydrogen pentaphosphate) metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901910 adenosine 5'-(hexahydrogen pentaphosphate) metabolism The chemical reactions and pathways involving adenosine 5'-(hexahydrogen pentaphosphate). GO:1901911 adenosine 5'-(hexahydrogen pentaphosphate) catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901911 adenosine 5'-(hexahydrogen pentaphosphate) breakdown|adenosine 5'-(hexahydrogen pentaphosphate) catabolism|adenosine 5'-(hexahydrogen pentaphosphate) degradation The chemical reactions and pathways resulting in the breakdown of adenosine 5'-(hexahydrogen pentaphosphate). GO:0045424 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045424 GO:0045425 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045425 GO:0045422 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045422 GO:0045423 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045423 GO:0045420 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045420 GO:0045421 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045421 GO:0045428 regulation of nitric oxide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045428 regulation of nitric oxide synthesis|regulation of nitric oxide formation|regulation of nitric oxide biosynthesis|regulation of nitric oxide anabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide. GO:0045429 positive regulation of nitric oxide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045429 stimulation of nitric oxide biosynthetic process|up-regulation of nitric oxide biosynthetic process|upregulation of nitric oxide biosynthetic process|positive regulation of nitric oxide anabolism|positive regulation of nitric oxide synthesis|up regulation of nitric oxide biosynthetic process|positive regulation of nitric oxide formation|activation of nitric oxide biosynthetic process|positive regulation of nitric oxide biosynthesis Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide. GO:0045426 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045426 GO:0045427 obsolete enzyme active site formation via (phospho-5'-guanosine)-L-histidine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045427 OBSOLETE. The transient guanylylation of peptidyl-histidine to form (phospho-5'-guanosine)-L-histidine. GO:1901918 negative regulation of exoribonuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901918 down-regulation of exoribonuclease activity|downregulation of exoribonuclease activity|down regulation of exoribonuclease activity|inhibition of exoribonuclease activity Any process that stops, prevents or reduces the frequency, rate or extent of exoribonuclease activity. GO:1901919 positive regulation of exoribonuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901919 up-regulation of exoribonuclease activity|activation of exoribonuclease activity|up regulation of exoribonuclease activity|upregulation of exoribonuclease activity Any process that activates or increases the frequency, rate or extent of exoribonuclease activity. GO:1901927 cadinene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901927 cadinene catabolism|cadinene degradation|cadinene breakdown The chemical reactions and pathways resulting in the breakdown of cadinene. GO:1901928 cadinene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901928 cadinene synthesis|cadinene formation|cadinene biosynthesis|cadinene anabolism The chemical reactions and pathways resulting in the formation of cadinene. GO:1901925 negative regulation of protein import into nucleus during spindle assembly checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901925 Kap121p transport inhibitory pathway|KTIP|negative regulation of protein import into nucleus during mitotic cell cycle spindle assembly checkpoint Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus, and that occurs as a response to the mitotic cell cycle spindle assembly checkpoint. In S. cerevisiae, this process involves inhibition of the karyopherin/importin Kap121p (also known as Pse1p), which acts as the specific nuclear import receptor for several proteins, including Glc7p. Glc7p functions in opposition to key spindle assembly checkpoint protein Aurora kinase (Ipl1p). GO:1901926 cadinene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901926 cadinene metabolism The chemical reactions and pathways involving cadinene. GO:1901923 negative regulation of sclerotium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901923 downregulation of sclerotium development|down regulation of sclerotium development|inhibition of sclerotium development|down-regulation of sclerotium development Any process that stops, prevents or reduces the frequency, rate or extent of sclerotium development. GO:1901924 positive regulation of sclerotium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901924 up regulation of sclerotium development|upregulation of sclerotium development|up-regulation of sclerotium development|activation of sclerotium development Any process that activates or increases the frequency, rate or extent of sclerotium development. GO:1901921 phosphorylation of RNA polymerase II C-terminal domain involved in recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901921 CTD domain phosphorylation of RNA polymerase II involved in recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex Any phosphorylation of RNA polymerase II C-terminal domain that is involved in recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex. GO:1901922 regulation of sclerotium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901922 Any process that modulates the frequency, rate or extent of sclerotium development. GO:0045435 lycopene epsilon cyclase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045435 lycopene cyclase Catalysis of the cyclization of an epsilon ring at one end of the lycopene molecule (psi, psi-carotene) to form delta-carotene (epsilon, psi-carotene). GO:0045436 lycopene beta cyclase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045436 RHEA:32219|MetaCyc:RXN1F-150 crtL|lycopene cyclase Catalysis of the cyclization of beta rings at one or both ends of the lycopene molecule (psi, psi-carotene) to form gamma-carotene or the bicyclic beta-carotene (beta, beta-carotene), respectively. GO:1901920 peptidyl-tyrosine dephosphorylation involved in activation of protein kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901920 peptidyl-tyrosine dephosphorylation involved in protein kinase activation Any peptidyl-tyrosine dephosphorylation that is involved in activation of protein kinase activity. GO:0045433 male courtship behavior, veined wing generated song production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045433 male courtship behavior, song production|male courtship behaviour, veined wing generated song production|male courtship behaviour, song production The process during wing vibration where the male insect produces a species-specific acoustic signal called a love song. GO:0045434 negative regulation of female receptivity, post-mating biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045434 down-regulation of female receptivity, post-mating|inhibition of female receptivity, post-mating|down regulation of female receptivity, post-mating|downregulation of female receptivity, post-mating Any process that stops, prevents or reduces the receptiveness of a female to male advances subsequent to mating. CHEBI:46470 uridine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46470 GO:0045431 flavonol synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045431 EC:1.14.20.6|RHEA:21088 flavonoid 2-oxoglutarate-dependent dioxygenase activity|FLS activity|dihydroflavonol,2-oxoglutarate:oxygen oxidoreductase activity Catalysis of the reaction: a dihydroflavonol + 2-oxoglurate + O2 = a flavonol + succinate + CO2 + H2O. GO:0045432 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045432 GO:0045430 chalcone isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045430 MetaCyc:CHALCONE-ISOMERASE-RXN|EC:5.5.1.6 flavanone lyase (decyclizing)|chalcone--flavonone isomerase activity|chalcone-flavanone isomerase activity Catalysis of the reaction: a chalcone = a flavanone. GO:0045439 isopenicillin-N epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045439 RHEA:20033|KEGG_REACTION:R04147|MetaCyc:5.1.1.17-RXN|EC:5.1.1.17 isopenicillin N epimerase activity|penicillin-N 5-amino-5-carboxypentanoyl-epimerase activity Catalysis of the reaction: isopenicillin N = penicillin N. CHEBI:141724 N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminosyl-(2->6)]-N-acetyl-beta-D-galactosaminyl-(1->4)-[N-acetyl-alpha-neuraminosyl-(2->3)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_141724 GO:0045437 uridine nucleosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045437 RHEA:15577|EC:3.2.2.3|KEGG_REACTION:R01080|MetaCyc:URIDINE-NUCLEOSIDASE-RXN uridine ribohydrolase activity|uridine hydrolase activity Catalysis of the reaction: H(2)O + uridine = ribofuranose + uracil. GO:0045438 delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045438 ACV synthetase activity Catalysis of the formation of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine from constituent amino acids and ATP in the presence of magnesium ions and dithioerythritol. UBERON:0003656 mesopodium bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003656 basipodium bone|mesopod bone|carpal/tarsal bone|mesopodial bone A bone that is part of a mesopodial skeleton. UBERON:0003657 limb joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003657 joint of limb|skeletal limb joint|joint of limb skeletal system Any joint that is part of a (free) limb. GO:1901929 alpha-copaene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901929 alpha-copaene metabolism The chemical reactions and pathways involving alpha-copaene. GO:1901938 (-)-exo-alpha-bergamotene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901938 (-)-exo-alpha-bergamotene metabolism The chemical reactions and pathways involving (-)-exo-alpha-bergamotene. GO:1901939 (-)-exo-alpha-bergamotene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901939 (-)-exo-alpha-bergamotene degradation|(-)-exo-alpha-bergamotene breakdown|(-)-exo-alpha-bergamotene catabolism The chemical reactions and pathways resulting in the breakdown of (-)-exo-alpha-bergamotene. GO:1901936 beta-caryophyllene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901936 beta-caryophyllene degradation|beta-caryophyllene breakdown|beta-caryophyllene catabolism The chemical reactions and pathways resulting in the breakdown of beta-caryophyllene. GO:1901937 beta-caryophyllene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901937 beta-caryophyllene biosynthesis|beta-caryophyllene anabolism|beta-caryophyllene synthesis|beta-caryophyllene formation The chemical reactions and pathways resulting in the formation of beta-caryophyllene. GO:1901934 bicyclogermacrene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901934 bicyclogermacrene anabolism|bicyclogermacrene synthesis|bicyclogermacrene formation|bicyclogermacrene biosynthesis The chemical reactions and pathways resulting in the formation of bicyclogermacrene. GO:1901935 beta-caryophyllene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901935 beta-caryophyllene metabolism The chemical reactions and pathways involving beta-caryophyllene. GO:1901932 bicyclogermacrene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901932 bicyclogermacrene metabolism The chemical reactions and pathways involving bicyclogermacrene. GO:1901933 bicyclogermacrene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901933 bicyclogermacrene degradation|bicyclogermacrene breakdown|bicyclogermacrene catabolism The chemical reactions and pathways resulting in the breakdown of bicyclogermacrene. GO:1901930 alpha-copaene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901930 alpha-copaene breakdown|alpha-copaene catabolism|alpha-copaene degradation The chemical reactions and pathways resulting in the breakdown of alpha-copaene. GO:0045446 endothelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045446 The process in which a mesodermal, bone marrow or neural crest cell acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium. GO:0045447 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045447 GO:1901931 alpha-copaene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901931 alpha-copaene anabolism|alpha-copaene synthesis|alpha-copaene formation|alpha-copaene biosynthesis The chemical reactions and pathways resulting in the formation of alpha-copaene. GO:0045444 fat cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045444 adipocyte differentiation|adipose cell differentiation|adipogenesis|adipocyte cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat. GO:0045445 myoblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045445 myoblast cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers. GO:0045442 deacetoxycephalosporin-C hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045442 MetaCyc:1.14.11.26-RXN|RHEA:16805|KEGG_REACTION:R05229|EC:1.14.11.26 deacetoxycephalosporin-C,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity|DAOC hydroxylase activity|deacetylcephalosporin C synthase activity|deacetoxycephalosporin C hydroxylase activity|3'-methylcephem hydroxylase activity|beta-lactam hydroxylase activity|DACS Catalysis of the reaction: 2-oxoglutarate + deacetoxycephalosporin C + O(2) = CO(2) + deacetylcephalosporin C + succinate. GO:0045443 juvenile hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045443 The regulated release of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis. GO:0045440 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045440 GO:0045441 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045441 GO:0045448 mitotic cell cycle, embryonic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045448 The eukaryotic cell cycle in which a cell is duplicated without changing ploidy, occurring in the embryo. CHEBI:141711 N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminosyl-(2->6)]-N-acetyl-beta-D-galactosaminyl-(1->4)-[N-acetyl-alpha-neuraminosyl-(2->8)-N-acetyl-alpha-neuraminosyl-(2->3)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_141711 GO:0045449 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045449 UBERON:0003643 respiratory system arterial blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003643 An arterial blood vessel that is part of a respiratory system [Automatically generated definition]. UBERON:0003644 kidney arterial blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003644 kidney arterial system An arterial blood vessel that is part of a kidney [Automatically generated definition]. SO:0002247 sncRNA biolink:SequenceFeature go-plus http://purl.obolibrary.org/obo/SO_0002247 Small noncoding RNA A non-coding RNA less than 200 nucleotides in length. GO:1901949 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901949 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate formation|5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate biosynthesis|5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate anabolism|5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate synthesis The chemical reactions and pathways resulting in the formation of 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate. GO:0045450 bicoid mRNA localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045450 establishment and maintenance of bicoid mRNA localization|bicoid mRNA localisation Any process in which bicoid mRNA is transported to and maintained within the oocyte as part of the specification of the anterior/posterior axis. CHEBI:22487 alpha-aminoacyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22487 GO:1901947 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901947 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate metabolism The chemical reactions and pathways involving 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate. CHEBI:22484 galactosamine oligosaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22484 CHEBI:22485 glucosamine oligosaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22485 GO:1901948 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901948 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate catabolism|5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate degradation|5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate breakdown The chemical reactions and pathways resulting in the breakdown of 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate. GO:1901945 miltiradiene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901945 miltiradiene catabolism|miltiradiene degradation|miltiradiene breakdown The chemical reactions and pathways resulting in the breakdown of miltiradiene. GO:1901946 miltiradiene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901946 miltiradiene anabolism|miltiradiene synthesis|miltiradiene formation|miltiradiene biosynthesis The chemical reactions and pathways resulting in the formation of miltiradiene. GO:1901943 (+)-epi-alpha-bisabolol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901943 (+)-epi-alpha-bisabolol anabolism|(+)-epi-alpha-bisabolol synthesis|(+)-epi-alpha-bisabolol formation|(+)-epi-alpha-bisabolol biosynthesis The chemical reactions and pathways resulting in the formation of (+)-epi-alpha-bisabolol. GO:1901944 miltiradiene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901944 miltiradiene metabolism The chemical reactions and pathways involving miltiradiene. GO:1901941 (+)-epi-alpha-bisabolol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901941 (+)-epi-alpha-bisabolol metabolism The chemical reactions and pathways involving (+)-epi-alpha-bisabolol. GO:0045457 ecdysteroid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045457 The regulated release of ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development. GO:1901942 (+)-epi-alpha-bisabolol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901942 (+)-epi-alpha-bisabolol catabolism|(+)-epi-alpha-bisabolol degradation|(+)-epi-alpha-bisabolol breakdown The chemical reactions and pathways resulting in the breakdown of (+)-epi-alpha-bisabolol. GO:0045458 recombination within rDNA repeats biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045458 recombination within ribosomal DNA repeats Genetic recombination within the DNA of the genes coding for ribosomal RNA. GO:0045455 ecdysteroid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045455 ecdysteroid metabolism The chemical reactions and pathways involving ecdysteroids, a group of polyhydroxylated ketosteroids ubiquitous in insects and other arthropods, in which they initiate post-embryonic development, including the metamorphosis of immature forms and the development of the reproductive system and the maturation of oocytes in adult females. GO:1901940 (-)-exo-alpha-bergamotene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901940 (-)-exo-alpha-bergamotene synthesis|(-)-exo-alpha-bergamotene formation|(-)-exo-alpha-bergamotene anabolism|(-)-exo-alpha-bergamotene biosynthesis The chemical reactions and pathways resulting in the formation of (-)-exo-alpha-bergamotene. GO:0045456 ecdysteroid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045456 ecdysteroid biosynthesis|ecdysteroid anabolism|ecdysteroid synthesis|ecdysteroid formation The chemical reactions and pathways resulting in the formation of ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development. GO:0045453 bone resorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045453 Wikipedia:Bone_resorption The process in which specialized cells known as osteoclasts degrade the organic and inorganic portions of bone, and endocytose and transport the degradation products. GO:0045454 cell redox homeostasis biolink:BiologicalProcess go-plus goslim_drosophila|goslim_metagenomics http://purl.obolibrary.org/obo/GO_0045454 Wikipedia:Redox regulation of cell redox homeostasis|regulation of redox homeostasis Any process that maintains the redox environment of a cell or compartment within a cell. CHEBI:22483 amino oligosaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22483 GO:0045451 pole plasm oskar mRNA localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045451 establishment and maintenance of oskar mRNA localization in pole plasm|establishment and maintenance of pole plasm oskar mRNA localization|pole plasm oskar mRNA localisation|oocyte pole plasm oskar mRNA localization Any process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm. CHEBI:22480 amino disaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22480 GO:0045452 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045452 GO:0070419 nonhomologous end joining complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070419 non-homologous end joining complex|NHEJ complex A protein complex that plays a role in DNA double-strand break repair via nonhomologous end joining. Such complexes typically contain a specialized DNA ligase (e.g. Lig4 in eukaryotes) and one or more proteins that bind to DNA ends. GO:0070417 cellular response to cold biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070417 cellular response to cold stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism. GO:0070418 DNA-dependent protein kinase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070418 DNA-dependent protein kinase, DNA-end-binding complex|DNA-PK complex|DNA-PK-Ku antigen complex A protein complex that is involved in the repair of DNA double-strand breaks and, in mammals, V(D)J recombination events. It consists of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) and the DNA end-binding heterodimer Ku. GO:0045459 iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl triiron tetrasulfide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045459 RESID:AA0326 iron incorporation into iron-sulphur cluster via tetrakis-L-cysteinyl triiron tetrasulphide The incorporation of iron into a 3Fe-4S iron-sulfur cluster via tetrakis-L-cysteinyl triiron tetrasulfide. GO:0070415 trehalose metabolism in response to cold stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070415 trehalose metabolic process involved in response to cold stress The chemical reactions and pathways involving trehalose that occur as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism. GO:0070416 trehalose metabolism in response to water deprivation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070416 trehalose metabolic process involved in response to water deprivation The chemical reactions and pathways involving trehalose that occur as a result of deprivation of water. GO:0070413 trehalose metabolism in response to stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070413 trehalose metabolic process involved in response to stress The chemical reactions and pathways involving trehalose that occur as a result of a stimulus indicating the organism is under stress. GO:0070414 trehalose metabolism in response to heat stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070414 trehalose metabolic process involved in response to heat stress The chemical reactions and pathways involving trehalose that occur as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism. GO:0070411 I-SMAD binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070411 Interacting selectively and non-covalently with an inhibitory SMAD signaling protein. GO:0070412 R-SMAD binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070412 receptor-regulated SMAD binding|pathway restricted SMAD binding|receptor regulated SMAD binding|pathway-restricted SMAD binding Interacting selectively and non-covalently with a receptor-regulated SMAD signaling protein. GO:0070410 co-SMAD binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070410 common partner SMAD binding|common-mediator SMAD binding|common-partner SMAD binding|common mediator SMAD binding Interacting selectively and non-covalently with a common mediator SMAD signaling protein. GO:0045460 sterigmatocystin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045460 sterigmatocystin metabolism The chemical reactions and pathways involving sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds. CHEBI:22497 aminobutanal biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22497 CHEBI:46442 vanadate(3-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46442 GO:0045461 sterigmatocystin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045461 sterigmatocystin anabolism|sterigmatocystin synthesis|sterigmatocystin formation|sterigmatocystin biosynthesis The chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds. UBERON:0003618 aorta tunica media biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003618 tunica media of trunk of aortic tree|dorsal aorta tunica media|adult aorta tunica media|tunica media of dorsal aorta|tunica media of aorta|trunk of aortic tree tunica media|tunica media of adult aorta The middle layer of the aorta wall, containing the smooth muscle layer and elastic fibers. GO:1901958 negative regulation of cutin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901958 inhibition of cutin synthesis|inhibition of cutin biosynthesis|inhibition of cutin formation|down regulation of cutin anabolism|down regulation of cutin synthesis|downregulation of cutin anabolism|down regulation of cutin formation|downregulation of cutin synthesis|down-regulation of cutin biosynthesis|negative regulation of cutin biosynthesis|down-regulation of cutin biosynthetic process|downregulation of cutin formation|negative regulation of cutin anabolism|down-regulation of cutin anabolism|negative regulation of cutin synthesis|down-regulation of cutin synthesis|downregulation of cutin biosynthetic process|negative regulation of cutin formation|down-regulation of cutin formation|downregulation of cutin biosynthesis|down regulation of cutin biosynthesis|down regulation of cutin biosynthetic process|inhibition of cutin anabolism|inhibition of cutin biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of cutin biosynthetic process. CHEBI:22495 aminobenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22495 GO:1901959 positive regulation of cutin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901959 upregulation of cutin biosynthesis|upregulation of cutin biosynthetic process|up-regulation of cutin formation|upregulation of cutin anabolism|upregulation of cutin synthesis|up-regulation of cutin biosynthesis|upregulation of cutin formation|up-regulation of cutin biosynthetic process|activation of cutin biosynthetic process|up regulation of cutin anabolism|positive regulation of cutin anabolism|activation of cutin biosynthesis|up regulation of cutin synthesis|positive regulation of cutin synthesis|activation of cutin anabolism|up regulation of cutin formation|positive regulation of cutin biosynthesis|positive regulation of cutin formation|up regulation of cutin biosynthesis|up regulation of cutin biosynthetic process|activation of cutin synthesis|up-regulation of cutin anabolism|activation of cutin formation|up-regulation of cutin synthesis Any process that activates or increases the frequency, rate or extent of cutin biosynthetic process. UBERON:0003619 aorta tunica intima biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003619 dorsal aorta tunica intima|tunica intima of trunk of aortic tree|tunica intima of aorta|tunica intima of adult aorta|trunk of aortic tree tunica intima|tunica intima of dorsal aorta|adult aorta tunica intima The innermost layer of the aorta, containing the endothelium and an inner elastic membrane. CHEBI:22496 aminobiphenyl biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22496 UBERON:0003616 bronchus elastic tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003616 bronchial trunk elastic tissue|elastic tissue of bronchi|elastic tissue of bronchial trunk|bronchi elastic tissue|textus connectivus elasticus of bronchi|textus connectivus elasticus of bronchial trunk|textus connectivus elasticus of bronchus|elastic tissue of bronchus|elastic connective tissue of bronchus|bronchi elastic connective tissue|bronchus textus connectivus elasticus|bronchial trunk elastic connective tissue|elastic connective tissue of bronchi|bronchial trunk textus connectivus elasticus|elastic connective tissue of bronchial trunk|bronchus elastic connective tissue|bronchi textus connectivus elasticus An elastic tissue that is part of a bronchus [Automatically generated definition]. GO:1901956 positive regulation of retrograde dense core granule transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901956 up regulation of retrograde dense core granule transport|activation of retrograde dense core granule transport|up-regulation of retrograde dense core granule transport|upregulation of retrograde dense core granule transport Any process that activates or increases the frequency, rate or extent of retrograde dense core granule transport. UBERON:0003617 trachea elastic tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003617 windpipe textus connectivus elasticus|windpipe elastic tissue|textus connectivus elasticus of windpipe|cartilaginous trachea textus connectivus elasticus|cartilaginous trachea elastic connective tissue|elastic tissue of windpipe|elastic connective tissue of cartilaginous trachea|textus connectivus elasticus of vertebrate trachea|cartilaginous trachea elastic tissue|elastic connective tissue of windpipe|elastic tissue of vertebrate trachea|elastic tissue of cartilaginous trachea|elastic connective tissue of vertebrate trachea|textus connectivus elasticus of cartilaginous trachea|windpipe elastic connective tissue|vertebrate trachea textus connectivus elasticus|vertebrate trachea elastic connective tissue|vertebrate trachea elastic tissue An elastic tissue that is part of a trachea [Automatically generated definition]. GO:1901957 regulation of cutin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901957 regulation of cutin anabolism|regulation of cutin synthesis|regulation of cutin formation|regulation of cutin biosynthesis Any process that modulates the frequency, rate or extent of cutin biosynthetic process. UBERON:0003614 blood vessel elastic tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003614 vascular elastic laminae|textus connectivus elasticus of blood vessel|blood vessel textus connectivus elasticus|elastic tissue of blood vessel|elastic connective tissue of blood vessel|vascular elastic tissue|vascular elastic lamina|elastic laminae|blood vessel elastic connective tissue|elastic lamina Elastic tissue layer that lines a blood vessel layer. GO:1901954 regulation of retrograde dense core granule transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901954 Any process that modulates the frequency, rate or extent of retrograde dense core granule transport. GO:1901955 negative regulation of retrograde dense core granule transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901955 downregulation of retrograde dense core granule transport|down-regulation of retrograde dense core granule transport|inhibition of retrograde dense core granule transport|down regulation of retrograde dense core granule transport Any process that stops, prevents or reduces the frequency, rate or extent of retrograde dense core granule transport. UBERON:0003615 lung elastic tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003615 elastic tissue of lung|elastic connective tissue of lung|lung textus connectivus elasticus|lung elastic connective tissue|pulmonary elastic fiber|textus connectivus elasticus of lung Elastic tissue that is part of a lung [Automatically generated definition]. GO:1901952 negative regulation of anterograde dense core granule transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901952 down-regulation of anterograde dense core granule transport|downregulation of anterograde dense core granule transport|down regulation of anterograde dense core granule transport|inhibition of anterograde dense core granule transport Any process that stops, prevents or reduces the frequency, rate or extent of anterograde dense core granule transport. GO:0045468 regulation of R8 cell spacing in compound eye biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045468 regulation of R8 spacing|R8 cell spacing in compound eye Any process that ensures that the R8 cells are selected in a precise progressive pattern so that they are evenly spaced throughout the eye disc. GO:0045469 negative regulation of R8 cell spacing in compound eye biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045469 down-regulation of R8 spacing|downregulation of R8 spacing|down regulation of R8 spacing|inhibition of R8 spacing Any process that stops or prevents the correct R8 cell spacing pattern in a compound eye. GO:1901953 positive regulation of anterograde dense core granule transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901953 up-regulation of anterograde dense core granule transport|activation of anterograde dense core granule transport|up regulation of anterograde dense core granule transport|upregulation of anterograde dense core granule transport Any process that activates or increases the frequency, rate or extent of anterograde dense core granule transport. CHEBI:22490 aminoadipate semialdehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22490 GO:1901950 dense core granule transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901950 dense core vesicle transport The directed movement a dense core granule within a cell. GO:0045466 R7 cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045466 The process in which a relatively unspecialized cell acquires the specialized features of the R7 photoreceptor. GO:0045467 R7 cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045467 The process whose specific outcome is the progression of the R7 photoreceptor over time, from its formation to the mature structure. The R7 photoreceptor is the last photoreceptor to develop in the ommatidium. GO:1901951 regulation of anterograde dense core granule transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901951 Any process that modulates the frequency, rate or extent of anterograde dense core granule transport. GO:0045464 R8 cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045464 The process in which a cell becomes capable of differentiating autonomously into an R8 cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. CHEBI:22493 aminobenzenesulfonate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22493 GO:0045465 R8 cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045465 The process in which a relatively unspecialized cell acquires the specialized features of the R8 photoreceptor. CHEBI:22494 aminobenzoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22494 GO:0045462 trichothecene 3-O-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045462 Catalysis of the 3-O-acetylation of a trichothecene. Trichothecenes are sesquiterpene epoxide mycotoxins that act as potent inhibitors of eukaryotic protein synthesis. GO:0045463 R8 cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045463 The process whose specific outcome is the progression of the R8 photoreceptor over time, from its formation to the mature structure. The R8 photoreceptor is the founding receptor of each ommatidium. CHEBI:22492 amino aldehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22492 GO:0070408 carbamoyl phosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070408 UM-BBD_pathwayID:bzn carbamoyl phosphate metabolism The chemical reactions and pathways involving carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways. GO:0070409 carbamoyl phosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070409 carbamoyl phosphate anabolism|carbamoyl phosphate synthesis|carbamoyl phosphate formation|carbamyl phosphate biosynthetic process|carbamoyl phosphate biosynthesis The chemical reactions and pathways resulting in the formation of carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways. GO:0070406 glutamine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070406 Interacting selectively and non-covalently with glutamine, 2,5-diamino-5-oxopentanoic acid. GO:0070407 oxidation-dependent protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070407 oxidation-dependent protein breakdown|oxidation-dependent proteolysis|oxidized protein catabolic process|oxidation-dependent protein degradation|oxidation-dependent protein catabolism The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the oxidation of one or more amino acid residues in the protein. GO:0070404 NADH binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070404 reduced nicotinamide adenine dinucleotide binding|reduced NAD binding|NAD (reduced) binding Interacting selectively and non-covalently with the reduced form, NADH, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions. GO:0070405 ammonium ion binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070405 ammonium binding Interacting selectively and non-covalently with ammonium ions (NH4+). GO:0070402 NADPH binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070402 NADP (reduced) binding|reduced nicotinamide adenine dinucleotide phosphate binding|reduced NADP binding Interacting selectively and non-covalently with the reduced form, NADPH, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions. GO:0070403 NAD+ binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070403 NAD (oxidized) binding|NAD binding|oxidized nicotinamide adenine dinucleotide binding|oxidized NAD binding Interacting selectively and non-covalently with the oxidized form, NAD, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions. GO:0070400 teichoic acid D-alanylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070400 teichoic acid alanylation The formation of a D-alanyl ester of teichoic acid. Alanylation of teichoic acids modulates the properties of the bacterial cell wall and modulates the inflammatory properties of the teichoic acid. GO:0070401 NADP+ binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070401 NADP binding|NADP (oxidized) binding|oxidized NADP binding|oxidized nicotinamide adenine dinucleotide phosphate binding Interacting selectively and non-covalently with the oxidized form, NADP+, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions. CHEBI:71402 3-phosphonatopyruvate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71402 CHEBI:71403 8-oxo-dAMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71403 CHEBI:71406 (R)-adrenaline(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71406 CHEBI:71407 3-oxooctadecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71407 CHEBI:71408 3-hydroxyoctadecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71408 CHEBI:71409 (beta-L-Ara4N)2-(KDO)2-lipid A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71409 CHEBI:71410 7-methyl-3-oxooct-6-enoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71410 CHEBI:71412 trans-2-octadecenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71412 CHEBI:71427 isotridecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71427 CHEBI:71429 deaminoneuraminic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71429 CHEBI:71435 3-hydroxyisopentadecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71435 CHEBI:71437 isotridecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71437 CHEBI:71439 3-oxoisopentadecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71439 CHEBI:71430 3-oxoisopentadecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71430 CHEBI:71443 3-hydroxyisopentadecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71443 CHEBI:537519 L-aspartic acid 4-semialdehyde betaine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_537519 CHEBI:71445 3-oxoisoheptadecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71445 CHEBI:71446 3-hydroxyisoheptadecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71446 CHEBI:71449 hexadec-9-enoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71449 CHEBI:141790 3-hydroxybutane-1,2,3-tricarboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_141790 CHEBI:71453 3-oxoisoheptadecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71453 CHEBI:71455 3-hydroxyicosanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71455 CHEBI:71456 3-hydroxydocosanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71456 CHEBI:71451 3-oxodocosanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71451 CHEBI:71464 palmitoyl ethanolamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71464 CHEBI:71465 palmitoleoyl ethanolamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71465 CHEBI:71466 oleoyl ethanolamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71466 CHEBI:71467 (5Z,8Z,11Z,14Z,17Z)-icosapentaenoylethanolamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71467 CHEBI:141772 2-hydroxydodecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_141772 CHEBI:71460 (E)-isopentadec-2-enoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71460 CHEBI:71461 isoheptadecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71461 CHEBI:71462 (E)-isoheptadec-2-enoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71462 GO:0070394 lipoteichoic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070394 LTA metabolic process|lipoteichoic acid metabolism The chemical reactions and pathways involving lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor. GO:0070395 lipoteichoic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070395 lipoteichoic acid biosynthesis|lipoteichoic acid anabolism|lipoteichoic acid synthesis|LTA biosynthetic process|lipoteichoic acid formation The chemical reactions and pathways resulting in the formation of lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor. GO:0070392 detection of lipoteichoic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070392 detection of LTA The series of events in which a lipoteichoic acid stimulus is received by a cell and converted into a molecular signal; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor. GO:0070393 teichoic acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070393 teichoic acid degradation|teichoic acid breakdown|teichoic acid catabolism The chemical reactions and pathways resulting in the breakdown of teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues. GO:0070390 transcription export complex 2 biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070390 TREX-2 complex|Sac3-Thp1-Sus1-Sem1-Cdc31 complex A protein complex that couples SAGA-dependent gene expression to mRNA export at the inner side of the nuclear pore complex (NPC). The TREX-2 complex is tethered to the inner side of the NPC via the nucleoporins Nup1 and Nup60; in S. cerevisiae it contains Sac3p, Thp1p, Sem1, Sus1p and Cdc31p. GO:0070391 response to lipoteichoic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070391 response to LTA Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoteichoic acid stimulus; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor. GO:0070398 wall teichoic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070398 wall teichoic acid anabolism|wall teichoic acid biosynthesis|wall teichoic acid synthesis|wall teichoic acid formation|WTA biosynthetic process The chemical reactions and pathways resulting in the formation of wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan. GO:0070399 wall teichoic acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070399 wall teichoic acid breakdown|wall teichoic acid catabolism|wall teichoic acid degradation The chemical reactions and pathways resulting in the breakdown of wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan. GO:0070396 lipoteichoic acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070396 lipoteichoic acid degradation|lipoteichoic acid catabolism|lipoteichoic acid breakdown The chemical reactions and pathways resulting in the breakdown of lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor. GO:0070397 wall teichoic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070397 wall teichoic acid metabolism|WTA metabolic process The chemical reactions and pathways involving wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan. GO:0070383 DNA cytosine deamination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070383 The removal of an amino group from a cytosine residue in DNA, forming a uracil residue. GO:0070384 Harderian gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070384 The process whose specific outcome is the progression of the Harderian gland over time, from its formation to the mature structure. The Harderian gland is an anterior orbital structure usually associated with the nictitating membrane, and produces and secretes a variety of substances to the eye, depending upon the species. GO:0070381 endosome to plasma membrane transport vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070381 endosome to plasma membrane constitutive secretory pathway transport vesicle|endosome-plasma membrane transport vesicle A transport vesicle that mediates transport from the endosome to the plasma membrane, and fuses with the plasma membrane to deliver lipids and membrane proteins to the plasma membrane and to release various cargo molecules, such as proteins or hormones, by exocytosis. GO:0070382 exocytic vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070382 exocytotic vesicle|exocytic constitutive secretory pathway transport vesicle A transport vesicle that mediates transport from an intracellular compartment to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis. GO:0070380 high mobility group box 1 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070380 HMGB1 receptor activity Combining with high mobility group box 1 (HMBGB1) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0070389 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0070389 GO:0070387 procollagen-proline 4-dioxygenase complex, alpha(II) type biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070387 prolyl 4-hydroxylase complex (alpha(II)-type)|procollagen-proline, 2-oxoglutarate-4-dioxygenase complex, alpha(II) type A procollagen-proline 4-dioxygenase complex that contains alpha subunits of the type II isoform; its activity is inhibited by poly(L-proline) only at high concentrations. GO:0070388 procollagen-proline 4-dioxygenase complex, alpha(III) type biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070388 procollagen-proline, 2-oxoglutarate-4-dioxygenase complex, alpha(III) type|prolyl 4-hydroxylase complex (alpha(III)-type) A procollagen-proline 4-dioxygenase complex that contains alpha subunits of the type III isoform. GO:0070385 egasyn-beta-glucuronidase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070385 A protein complex that contains beta-glucuronidase and the carboxyl esterase egasyn; formation of the complex causes beta-glucuronidase to be retained in the endoplasmic reticulum. GO:0070386 procollagen-proline 4-dioxygenase complex, alpha(I) type biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070386 procollagen-proline, 2-oxoglutarate-4-dioxygenase complex, alpha(I) type|prolyl 4-hydroxylase complex (alpha(I)-type) A procollagen-proline 4-dioxygenase complex that contains alpha subunits of the type I isoform; its activity is readily inhibited by poly(L-proline). UBERON:0037089 wall of orbit biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0037089 orbit wall UBERON:0037094 wall of common carotid artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0037094 common carotid arterial wall UBERON:0013069 popliteal area biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0013069 popliteal region|popliteal fossa|knee pit|popliteal space A depression on the ventral side of the femur, at the knee joint, between the condyles. GO:0045350 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045350 GO:0045351 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045351 GO:1901848 nicotinate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901848 nicotinate catabolism|nicotinate degradation|nicotinate breakdown The chemical reactions and pathways resulting in the breakdown of nicotinate. GO:1901849 nicotinate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901849 nicotinate biosynthesis|nicotinate anabolism|nicotinate synthesis|nicotinate formation The chemical reactions and pathways resulting in the formation of nicotinate. GO:1901846 positive regulation of cell communication by electrical coupling involved in cardiac conduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901846 upregulation of cell communication by electrical coupling involved in cardiac conduction|up-regulation of cell communication by electrical coupling involved in cardiac conduction|activation of cell communication by electrical coupling involved in cardiac conduction|up regulation of cell communication by electrical coupling involved in cardiac conduction Any process that activates or increases the frequency, rate or extent of cell communication by electrical coupling involved in cardiac conduction. GO:1901847 nicotinate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901847 nicotinate metabolism The chemical reactions and pathways involving nicotinate. CHEBI:22469 alpha-terpineol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_22469 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901844 Any process that modulates the frequency, rate or extent of cell communication by electrical coupling involved in cardiac conduction. GO:1901845 negative regulation of cell communication by electrical coupling involved in cardiac conduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901845 downregulation of cell communication by electrical coupling involved in cardiac conduction|down regulation of cell communication by electrical coupling involved in cardiac conduction|inhibition of cell communication by electrical coupling involved in cardiac conduction|down-regulation of cell communication by electrical coupling involved in cardiac conduction Any process that stops, prevents or reduces the frequency, rate or extent of cell communication by electrical coupling involved in cardiac conduction. GO:0045358 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045358 GO:1901842 negative regulation of high voltage-gated calcium channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901842 negative regulation of high voltage gated calcium channel activity|down-regulation of high voltage gated calcium channel activity|inhibition of high voltage-dependent calcium channel activity|down regulation of high voltage-gated calcium channel activity|downregulation of high voltage-gated calcium channel activity|inhibition of high voltage gated calcium channel activity|down regulation of high voltage-dependent calcium channel activity|downregulation of high voltage-dependent calcium channel activity|down regulation of high voltage gated calcium channel activity|down-regulation of high voltage-gated calcium channel activity|downregulation of high voltage gated calcium channel activity|down-regulation of high voltage-dependent calcium channel activity|negative regulation of high voltage-dependent calcium channel activity|inhibition of high voltage-gated calcium channel activity Any process that stops, prevents or reduces the frequency, rate or extent of high voltage-gated calcium channel activity. GO:1901843 positive regulation of high voltage-gated calcium channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901843 positive regulation of high voltage gated calcium channel activity|up-regulation of high voltage-dependent calcium channel activity|activation of high voltage gated calcium channel activity|upregulation of high voltage-gated calcium channel activity|up-regulation of high voltage gated calcium channel activity|upregulation of high voltage-dependent calcium channel activity|up regulation of high voltage-gated calcium channel activity|activation of high voltage-gated calcium channel activity|upregulation of high voltage gated calcium channel activity|up regulation of high voltage-dependent calcium channel activity|positive regulation of high voltage-dependent calcium channel activity|up regulation of high voltage gated calcium channel activity|activation of high voltage-dependent calcium channel activity|up-regulation of high voltage-gated calcium channel activity Any process that activates or increases the frequency, rate or extent of high voltage-gated calcium channel activity. GO:0045359 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045359 GO:0045356 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045356 GO:1901840 negative regulation of RNA polymerase I regulatory region sequence-specific DNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901840 down-regulation of RNA polymerase I regulatory region sequence-specific DNA binding|downregulation of RNA polymerase I regulatory region sequence-specific DNA binding|down regulation of RNA polymerase I regulatory region sequence-specific DNA binding|inhibition of RNA polymerase I regulatory region sequence-specific DNA binding Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase I regulatory region sequence-specific DNA binding. GO:1901841 regulation of high voltage-gated calcium channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901841 regulation of high voltage-dependent calcium channel activity|regulation of high voltage gated calcium channel activity Any process that modulates the frequency, rate or extent of high voltage-gated calcium channel activity. GO:0045357 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045357 GO:0045354 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045354 GO:0045355 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045355 GO:0045352 interleukin-1 type I receptor antagonist activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045352 IL-1ra type I Blocks the binding of interleukin-1 to interleukin-1 type I receptors. CHEBI:46430 (-)-alpha-tocopherol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46430 GO:0060990 lipid tube assembly involved in organelle fission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060990 lipid tubulation involved in organelle fission The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as organelles undergo fission. GO:0045353 interleukin-1 type II receptor antagonist activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045353 IL-1ra type II Blocks the binding of interleukin-1 to interleukin-1 type II receptors. GO:0060991 obsolete lipid tube assembly involved in cytokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060991 lipid tube assembly involved in cytokinesis|lipid tubulation involved in cytokinesis OBSOLETE. The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in cytokinesis. UBERON:0003692 acromioclavicular joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003692 acromioclavicular articulation|articulatio acromioclavicularis|scapuloclavicular articulation Any joint connecting the acromonion of the scapula and clavicle. UBERON:0003693 retroperitoneal space biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003693 retroperitoneum|spatium retroperitoneale Anatomical space in the abdominal cavity behind (retro) the peritoneum. It has no specific delineating anatomical structures. Organs are retroperitoneal if they only have peritoneum on their anterior side. GO:0060992 response to fungicide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060992 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fungicide stimulus. Fungicides are chemicals used to kill fungi. GO:0060993 kidney morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060993 Morphogenesis of a kidney. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. UBERON:0003691 epidural space biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003691 spatium epidurale|cavum epidurale|epidural cavity|extradural space|spatium extradurale|cavum extradurale The outermost part of the spinal canal. It is the space within the canal (formed by the surrounding vertebrae) lying outside the dura mater. GO:0060994 regulation of transcription from RNA polymerase II promoter involved in kidney development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060994 Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the branching morphogenesis by which the kidney progresses from its initial formation to the mature state. GO:0060995 cell-cell signaling involved in kidney development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060995 cell-cell signalling involved in kidney development Any process that mediates the transfer of information from one cell to another and contributes to the progression of the kidney over time, from its formation to the mature organ. GO:0070318 positive regulation of G0 to G1 transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070318 A cell cycle process that activates or increases the rate or extent of the transition from the G0 quiescent state to the G1 phase. GO:0070319 Golgi to plasma membrane transport vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070319 Golgi to plasma membrane constitutive secretory pathway transport vesicle|Golgi-plasma membrane transport vesicle A transport vesicle that mediates transport from the Golgi to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis. GO:0060996 dendritic spine development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060996 The process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission. GO:0060997 dendritic spine morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060997 The process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission. GO:0070316 regulation of G0 to G1 transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070316 A cell cycle process that modulates the rate or extent of the transition from the G0 quiescent state to the G1 phase. GO:0070317 negative regulation of G0 to G1 transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070317 maintenance of G0 arrest|maintenance of G0 phase|maintenance of cell quiescence|maintenance of cell cycle quiescence A cell cycle process that stops, prevents, or reduces the rate or extent of the transition from the G0 quiescent state to the G1 phase. GO:0060998 regulation of dendritic spine development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060998 Any process that modulates the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure. GO:0070314 G1 to G0 transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070314 establishment of cell quiescence|cell cycle quiescence|stationary phase|G1/G0 transition A cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters a specialized resting state known as G0 or quiescence. GO:0060999 positive regulation of dendritic spine development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060999 Any process that increases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure. GO:0070315 G1 to G0 transition involved in cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070315 G1/G0 transition involved in cell differentiation A cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters G0 phase, in the context of cell differentiation. GO:0070312 RAD52-ERCC4-ERCC1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070312 A nucleotide-excision repair complex formed by the association of the heterodimeric endonuclease XPF/ERCC4-ERCC1 (Rad1p and Rad10p in S. cerevisiae) with the RAD52 protein. GO:0070313 RGS6-DNMT1-DMAP1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070313 A protein complex formed by the association of RGS6, a negative regulator of heterotrimeric G protein signaling, with the DMAP1-Dnmt1 transcriptional repressor complex; in the complex, RGS6 inhibits the transcriptional repressor activity of DMAP1. GO:0070310 ATR-ATRIP complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070310 Mec1-Lcd1 complex|Rad3-Rad26 complex A protein complex that contains the protein kinase ATR and ATR-interacting protein (ATRIP) and binds single-stranded DNA; ssDNA binding affinity is increased in the presence of replication protein A. UBERON:0003696 metatarsophalangeal joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003696 metatarsophalangeal articulation|metatarsal joint|metatarsalphalangeal joint|articulationes metatarsophalangeae|metatarsal-phalangeal joint|metatarsophalangeal The metatarsophalangeal articulations are the joints between the metatarsal bones of the foot and the proximal bones of the toes . They are condyloid joints meaning an elliptical or rounded surface (of the metatarsal bones) come close to the shallow cavities (of the proximal phalanges). The ligaments are the plantar and two collateral. UBERON:0003697 abdominal wall biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003697 layers of the abdominal wall|paries abdominalis|wall of abdomen proper|wall of abdomen|abdominal wall proper|paries abdominalis The tissues that surround the organs that are present within the abdominal cavity. The abdominal wall tissue is composed of layers of fat, parietal peritoneum, fascia, and muscles. GO:0070311 nucleosomal methylation activator complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070311 NUMAC A protein complex that contains eight subunits in common with the SWI/SNF complex, plus the ATPase BRG1 (SMARCA4) and the histone methyltransferase CARM1; the complex is involved in regulating nuclear receptor-dependent transcription. UBERON:0003694 atlanto-axial joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003694 lateral atlanto-axial joint|atlanto axial joint|atlantoaxial joint|median atlanto-axial joint|articulatio atlantoepistrophica|atlantoaxial|articulatio atlantoaxialis The Atlanto-axial joint is of a complicated nature, comprising no fewer than four distinct joints. There is a pivot articulation between the odontoid process of the axis and the ring formed by the anterior arch and the transverse ligament of the atlas. UBERON:0003695 metacarpophalangeal joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003695 MP joint|metacarpal joint|articulationes metacarpophalangeae|carpometacarpophalangeal joint|metacarpo-phalangeal joint|metacarpal phalangeal joint The metacarpophalangeal joints (MCP) are of the condyloid kind, formed by the reception of the rounded heads of the metacarpal bones into shallow cavities on the proximal ends of the first phalanges, with the exception of that of the thumb, which presents more of the characters of a ginglymoid joint. Arthritis of the MCP is a distinguishing feature of Rheumatoid Arthritis, as opposed to the distal interphalangeal joint in osteoarthritis. [WP,unvetted]. CHEBI:22475 amino acid amide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22475 GO:0045361 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045361 GO:0045362 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045362 GO:1901859 negative regulation of mitochondrial DNA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901859 downregulation of mtDNA metabolic process|downregulation of mitochondrial DNA metabolism|down regulation of mitochondrial DNA metabolism|negative regulation of mtDNA metabolism|down-regulation of mtDNA metabolism|negative regulation of mtDNA metabolic process|down-regulation of mtDNA metabolic process|down regulation of mitochondrial DNA metabolic process|inhibition of mitochondrial DNA metabolism|downregulation of mitochondrial DNA metabolic process|downregulation of mtDNA metabolism|down regulation of mtDNA metabolism|inhibition of mtDNA metabolic process|down-regulation of mitochondrial DNA metabolic process|down-regulation of mitochondrial DNA metabolism|negative regulation of mitochondrial DNA metabolism|inhibition of mtDNA metabolism|down regulation of mtDNA metabolic process|inhibition of mitochondrial DNA metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial DNA metabolic process. GO:0045360 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045360 CHEBI:22479 amino cyclitol glycoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22479 GO:1901857 positive regulation of cellular respiration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901857 up regulation of respiration|positive regulation of respiration|upregulation of oxidative metabolism|upregulation of oxidative metabolic process|upregulation of cellular respiration|activation of respiration|up-regulation of oxidative metabolism|up regulation of oxidative metabolic process|up-regulation of respiration|activation of cellular respiration|up-regulation of cellular respiration|positive regulation of oxidative metabolic process|activation of oxidative metabolism|activation of oxidative metabolic process|upregulation of respiration|positive regulation of oxidative metabolism|up regulation of oxidative metabolism|up-regulation of oxidative metabolic process|up regulation of cellular respiration Any process that activates or increases the frequency, rate or extent of cellular respiration. GO:1901858 regulation of mitochondrial DNA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901858 regulation of mitochondrial DNA metabolism|regulation of mtDNA metabolism|regulation of mtDNA metabolic process Any process that modulates the frequency, rate or extent of mitochondrial DNA metabolic process. GO:1901855 5,6,7,8-tetrahydrosarcinapterin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901855 5,6,7,8-tetrahydrosarcinapterin anabolism|5,6,7,8-tetrahydrosarcinapterin synthesis|5,6,7,8-tetrahydrosarcinapterin formation|5,6,7,8-tetrahydrosarcinapterin biosynthesis The chemical reactions and pathways resulting in the formation of 5,6,7,8-tetrahydrosarcinapterin. GO:1901856 negative regulation of cellular respiration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901856 downregulation of respiration|downregulation of cellular respiration|inhibition of oxidative metabolic process|down regulation of oxidative metabolism|down regulation of cellular respiration|inhibition of cellular respiration|down regulation of oxidative metabolic process|negative regulation of respiration|down-regulation of respiration|inhibition of oxidative metabolism|downregulation of oxidative metabolic process|inhibition of respiration|negative regulation of oxidative metabolism|down-regulation of oxidative metabolism|negative regulation of oxidative metabolic process|down-regulation of oxidative metabolic process|down-regulation of cellular respiration|down regulation of respiration|downregulation of oxidative metabolism Any process that stops, prevents or reduces the frequency, rate or extent of cellular respiration. CHEBI:22478 amino alcohol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22478 GO:1901853 5,6,7,8-tetrahydrosarcinapterin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901853 5,6,7,8-tetrahydrosarcinapterin metabolism The chemical reactions and pathways involving 5,6,7,8-tetrahydrosarcinapterin. GO:0045369 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045369 GO:1901854 5,6,7,8-tetrahydrosarcinapterin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901854 5,6,7,8-tetrahydrosarcinapterin catabolism|5,6,7,8-tetrahydrosarcinapterin degradation|5,6,7,8-tetrahydrosarcinapterin breakdown The chemical reactions and pathways resulting in the breakdown of 5,6,7,8-tetrahydrosarcinapterin. GO:1901851 7,8-didemethyl-8-hydroxy-5-deazariboflavin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901851 coenzyme F0 catabolism|7,8-didemethyl-8-hydroxy-5-deazariboflavin catabolism|7,8-didemethyl-8-hydroxy-5-deazariboflavin degradation|coenzyme F0 degradation|7,8-didemethyl-8-hydroxy-5-deazariboflavin breakdown|coenzyme F0 breakdown|coenzyme F0 catabolic process The chemical reactions and pathways resulting in the breakdown of 7,8-didemethyl-8-hydroxy-5-deazariboflavin. GO:0045367 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045367 GO:1901852 7,8-didemethyl-8-hydroxy-5-deazariboflavin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901852 coenzyme F0 anabolism|7,8-didemethyl-8-hydroxy-5-deazariboflavin synthesis|7,8-didemethyl-8-hydroxy-5-deazariboflavin formation|coenzyme F0 synthesis|coenzyme F0 formation|coenzyme F0 biosynthesis|coenzyme F0 biosynthetic process|7,8-didemethyl-8-hydroxy-5-deazariboflavin biosynthesis|7,8-didemethyl-8-hydroxy-5-deazariboflavin anabolism The chemical reactions and pathways resulting in the formation of 7,8-didemethyl-8-hydroxy-5-deazariboflavin. GO:0045368 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045368 GO:0045365 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045365 GO:1901850 7,8-didemethyl-8-hydroxy-5-deazariboflavin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901850 coenzyme F0 metabolism|7,8-didemethyl-8-hydroxy-5-deazariboflavin metabolism The chemical reactions and pathways involving 7,8-didemethyl-8-hydroxy-5-deazariboflavin. GO:0045366 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045366 GO:0045363 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045363 CHEBI:22470 alpha-tocopherol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22470 GO:0045364 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045364 GO:0060980 cell migration involved in coronary vasculogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060980 The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form the blood vessels of the heart. UBERON:0003682 palatal muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003682 musculi palati mollis et faucium|palate muscle|palatal muscle|musculi palati mollis et faucium|muscle of palate|palatine muscle The muscles of the palate are the glossopalatine, palatoglossus, levator palati(ni), musculus uvulae, palatopharyngeus, and tensor palati(ni). GO:0060981 cell migration involved in coronary angiogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060981 The orderly movement of a cell from one site to another that will contribute to the formation of new blood vessels in the heart from pre-existing blood vessels. GO:0070309 lens fiber cell morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070309 lens fibre cell morphogenesis|elongation of lens fiber cell|lens fiber cell morphogenesis during differentiation The process in which the structures of a lens fiber cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a lens fiber cell. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye. GO:0060982 coronary artery morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060982 The process in which the anatomical structures of coronary arteries are generated and organized. Coronary arteries are blood vessels that transport blood to the heart muscle. GO:0060983 epicardium-derived cardiac vascular smooth muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060983 The process in which a relatively unspecialized cell derived from the epicardium acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers. GO:0070307 lens fiber cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070307 lens fibre cell development The process whose specific outcome is the progression of a lens fiber cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a lens fiber cell fate. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye. GO:0060984 epicardium-derived cardiac vascular smooth muscle cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060984 The process whose specific outcome is the progression of a cardiac vascular smooth muscle cell that was derived from the epicardium over time, from its formation to the mature state. GO:0070308 lens fiber cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070308 lens fibre cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a lens fiber cell. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye. GO:0060985 epicardium-derived cardiac vascular smooth muscle cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060985 The commitment of an epicardial cell to a cardiac vascular smooth muscle cell fate and its capacity to differentiate into a cardiac vascular smooth muscle cell. GO:0060986 endocrine hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060986 The regulated release of a hormone into the circulatory system. GO:0070305 response to cGMP biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070305 response to 3',5'-cGMP|response to cyclic GMP|response to 3',5' cGMP|response to guanosine 3',5'-cyclophosphate Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cGMP (cyclic GMP, guanosine 3',5'-cyclophosphate) stimulus. GO:0060987 lipid tube biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0060987 A macromolecular complex that contains a tube of lipid surrounded by a protein coat. GO:0070306 lens fiber cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070306 lens fibre cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a lens fiber cell, any of the elongated, tightly packed cells that make up the bulk of the mature lens in the camera-type eye. The cytoplasm of a lens fiber cell is devoid of most intracellular organelles including the cell nucleus, and contains primarily crystallins, a group of water-soluble proteins expressed in vary large quantities. GO:0070303 negative regulation of stress-activated protein kinase signaling cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070303 negative regulation of stress-activated protein kinase signaling pathway|down-regulation of stress-activated protein kinase signaling pathway|negative regulation of SAPK signaling pathway|inhibition of stress-activated protein kinase signaling pathway|negative regulation of stress-activated protein kinase signalling pathway|down regulation of stress-activated protein kinase signaling pathway|downregulation of stress-activated protein kinase signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade. GO:0060988 lipid tube assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060988 lipid tubulation The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as they fuse or undergo fission. GO:0070304 positive regulation of stress-activated protein kinase signaling cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070304 stimulation of stress-activated protein kinase signaling pathway|up-regulation of stress-activated protein kinase signaling pathway|positive regulation of SAPK signaling pathway|upregulation of stress-activated protein kinase signaling pathway|positive regulation of stress-activated protein kinase signalling pathway|positive regulation of stress-activated protein kinase signaling pathway|up regulation of stress-activated protein kinase signaling pathway|activation of stress-activated protein kinase signaling pathway Any process that activates or increases the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade. GO:0060989 lipid tube assembly involved in organelle fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060989 lipid tubulation involved in organelle fusion The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as organelles fuse. GO:0070301 cellular response to hydrogen peroxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070301 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus. UBERON:0003687 foramen magnum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003687 In anatomy, in the occipital bone, the foramen magnum is one of the several oval or circular apertures in the base of the skull, through which the medulla oblongata (an extension of the spinal cord) enters and exits the skull vault. Apart from the transmission of the medulla oblongata and its membranes, the foramen magnum transmits the Spinal Accessory nerve, vertebral arteries, the anterior and posterior spinal arteries, the membrana tectoria and alar ligaments. [WP,unvetted]. GO:0070302 regulation of stress-activated protein kinase signaling cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070302 regulation of SAPK signaling pathway|regulation of stress-activated protein kinase signaling pathway|regulation of stress-activated protein kinase signalling pathway Any process that modulates the frequency, rate or extent of signaling via a stress-activated protein kinase signaling cascade. UBERON:0003685 cranial suture biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003685 suture joint of skull|cranium suture|suture|sutura|suture of cranium Fibrous joint in which the articulating bones or cartilages of the skull are connected by sutural ligaments (scant amount of collagenous dense connective tissue). Examples: sagittal suture, frontal suture. GO:0070300 phosphatidic acid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070300 phosphatidate binding Interacting selectively and non-covalently with phosphatidic acid, any of a class of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids. UBERON:0003684 abdominal cavity biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003684 space of abdominal compartment|cavity of compartment of abdomen|cavity of abdominal compartment|cavitas abdominis The part of the ventral body cavity that is within the abdomen proper (excluding the pelvic cavity). GO:0045372 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045372 GO:0045373 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045373 GO:0045370 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045370 CHEBI:22440 alpha-N-substituted L-arginine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22440 GO:0045371 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045371 GO:1901868 ecgonine methyl ester catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901868 ecgonine methyl ester degradation|ecgonine methyl ester breakdown|ecgonine methyl ester catabolism The chemical reactions and pathways resulting in the breakdown of ecgonine methyl ester. GO:1901869 ecgonine methyl ester biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901869 ecgonine methyl ester formation|ecgonine methyl ester biosynthesis|ecgonine methyl ester anabolism|ecgonine methyl ester synthesis The chemical reactions and pathways resulting in the formation of ecgonine methyl ester. GO:1901866 capsorubin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901866 capsorubin synthesis|capsorubin formation|capsorubin biosynthesis|capsorubin anabolism The chemical reactions and pathways resulting in the formation of capsorubin. GO:1901867 ecgonine methyl ester metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901867 ecgonine methyl ester metabolism The chemical reactions and pathways involving ecgonine methyl ester. CHEBI:22445 alpha-aspartyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22445 GO:1901864 capsorubin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901864 capsorubin metabolism The chemical reactions and pathways involving capsorubin. GO:1901865 capsorubin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901865 capsorubin degradation|capsorubin catabolism|capsorubin breakdown The chemical reactions and pathways resulting in the breakdown of capsorubin. GO:0045378 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045378 GO:1901862 negative regulation of muscle tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901862 down regulation of muscle tissue development|downregulation of muscle tissue development|down-regulation of muscle tissue development|inhibition of muscle tissue development Any process that stops, prevents or reduces the frequency, rate or extent of muscle tissue development. OBO:GOCHE_76838 substance with EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_76838 GO:1901863 positive regulation of muscle tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901863 upregulation of muscle tissue development|up regulation of muscle tissue development|activation of muscle tissue development|up-regulation of muscle tissue development Any process that activates or increases the frequency, rate or extent of muscle tissue development. GO:0045379 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045379 GO:1901860 positive regulation of mitochondrial DNA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901860 upregulation of mtDNA metabolism|activation of mitochondrial DNA metabolism|upregulation of mtDNA metabolic process|positive regulation of mitochondrial DNA metabolism|up-regulation of mitochondrial DNA metabolic process|up regulation of mitochondrial DNA metabolism|up-regulation of mtDNA metabolism|up regulation of mtDNA metabolic process|positive regulation of mtDNA metabolic process|activation of mtDNA metabolism|upregulation of mitochondrial DNA metabolic process|upregulation of mitochondrial DNA metabolism|activation of mtDNA metabolic process|positive regulation of mtDNA metabolism|up regulation of mtDNA metabolism|up-regulation of mtDNA metabolic process|up regulation of mitochondrial DNA metabolic process|activation of mitochondrial DNA metabolic process|up-regulation of mitochondrial DNA metabolism Any process that activates or increases the frequency, rate or extent of mitochondrial DNA metabolic process. GO:0045376 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045376 GO:0045377 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045377 GO:1901861 regulation of muscle tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901861 Any process that modulates the frequency, rate or extent of muscle tissue development. GO:0045374 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045374 GO:0045375 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045375 GO:0070338 5'-flap-structured DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070338 Interacting selectively and non-covalently with a 5'-flap structure in DNA. A DNA flap structure is one in which a single-stranded 5'-end of DNA or RNA protrudes from a double-stranded DNA molecule. 5'-flap structures can be formed during DNA repair or lagging strand synthesis; in the latter case RNA flaps form from lagging strand RNA primers. GO:0070339 response to bacterial lipopeptide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070339 Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipopeptide stimulus. GO:0070336 flap-structured DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070336 Interacting selectively and non-covalently with a flap structure in DNA. A DNA flap structure is one in which a single-stranded length of DNA or RNA protrudes from a double-stranded DNA molecule. GO:0070337 3'-flap-structured DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070337 Interacting selectively and non-covalently with a 3'-flap structure in DNA. A DNA flap structure is one in which a single-stranded 3'-end of DNA or RNA protrudes from a double-stranded DNA molecule. GO:0070334 alpha6-beta4 integrin-laminin 5 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070334 alpha6-beta4 integrin-laminin-332 complex|ITGA6-ITGB4-LAMA5 complex A protein complex that consists of an alpha6-beta4 integrin complex bound to laminin 5. GO:0070335 aspartate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070335 aspartic acid binding Interacting selectively and non-covalently with aspartate, the alpha-amino-acid anion of 2-aminobutanedioic acid that has formula C4H5NO4. GO:0070332 CD20-Lck-Lyn-Fyn complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070332 A protein complex that contains the cell-surface protein CD20 and the Src family tyrosine kinases Lck, Lyn and Fyn. GO:0070333 alpha6-beta4 integrin-Shc-Grb2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070333 ITGA6-ITGB4-SHC-GRB2 complex A protein complex that consists of an alpha6-beta4 integrin complex bound to the adaptor proteins Shc and Grb2. UBERON:0003672 dentition biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003672 teeth set|teeth|teeth|set of teeth|collection of teeth|dentes A collection of teeth arranged in some pattern in the mouth or other part of the body. The arrangement may be a simple row, a collection of rows, or a more elaborate structure, such as a toooth whorl. GO:0070330 aromatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070330 RHEA:17149|MetaCyc:UNSPECIFIC-MONOOXYGENASE-RXN|EC:1.14.14.1|UM-BBD_enzymeID:e0551 estrogen synthetase activity Catalysis of the reduction of an aliphatic ring to yield an aromatic ring. GO:0070331 CD20-Lck-Fyn complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070331 A protein complex that contains the cell-surface protein CD20 and the Src family tyrosine kinases Lck and Fyn. GO:0045383 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045383 CHEBI:22453 alpha-glutamyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22453 GO:0045384 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045384 GO:0045381 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045381 GO:0045382 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045382 GO:1901879 regulation of protein depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901879 regulation of protein polymer catabolism|regulation of protein polymer degradation|regulation of protein polymer breakdown|regulation of protein polymer catabolic process Any process that modulates the frequency, rate or extent of protein depolymerization. GO:0045380 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045380 GO:1901877 negative regulation of calcium ion binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901877 down-regulation of calcium ion storage activity|negative regulation of calcium ion storage activity|inhibition of calcium ion binding|downregulation of calcium ion storage activity|down regulation of calcium ion storage activity|down regulation of calcium ion binding|inhibition of calcium ion storage activity|downregulation of calcium ion binding|down-regulation of calcium ion binding Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion binding. UBERON:0003658 hip muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003658 hip muscle organ|muscle organ of hip region|muscle organ of hip|muscle organ of regio coxae|hip region muscle organ|regio coxae muscle organ Any muscle organ that is part of a hip [Automatically generated definition]. CHEBI:22455 alpha-hydroxynitrile biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22455 GO:1901878 positive regulation of calcium ion binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901878 positive regulation of calcium ion storage activity|up regulation of calcium ion storage activity|up-regulation of calcium ion binding|upregulation of calcium ion binding|upregulation of calcium ion storage activity|up-regulation of calcium ion storage activity|up regulation of calcium ion binding|activation of calcium ion binding|activation of calcium ion storage activity Any process that activates or increases the frequency, rate or extent of calcium ion binding. UBERON:0003659 pedal digit muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003659 foot digit muscle|muscle organ of terminal segment of free lower limb digit|digit of terminal segment of free lower limb muscle organ|hind limb digit muscle|terminal segment of free lower limb digit muscle organ|foot digit muscle organ|muscle organ of foot digit|muscle organ of digit of terminal segment of free lower limb|muscle organ of toe|digitus pedis muscle organ|digit of foot muscle organ|foot digit muscle|muscle organ of digit of foot|muscle organ of digitus pedis|toe muscle organ Any muscle organ that is part of a toe [Automatically generated definition]. GO:1901875 positive regulation of post-translational protein modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901875 up regulation of posttranslational modification|positive regulation of posttranslational protein modification|up regulation of post-translational modification|up regulation of posttranslational protein modification|up-regulation of posttranslational amino acid modification|positive regulation of post-translational modification|up regulation of post-translational protein modification|up regulation of PTM|up-regulation of post-translational amino acid modification|activation of post-translational protein modification|positive regulation of PTM|upregulation of posttranslational modification|activation of post-translational modification|upregulation of posttranslational protein modification|activation of post-translational amino acid modification|upregulation of posttranslational amino acid modification|activation of PTM|up-regulation of post-translational modification|positive regulation of post-translational amino acid modification|up-regulation of posttranslational modification|up-regulation of post-translational protein modification|up regulation of post-translational amino acid modification|up-regulation of PTM|up-regulation of posttranslational protein modification|up regulation of posttranslational amino acid modification|upregulation of post-translational modification|positive regulation of posttranslational amino acid modification|activation of posttranslational modification|upregulation of post-translational protein modification|activation of posttranslational protein modification|upregulation of PTM|upregulation of post-translational amino acid modification|activation of posttranslational amino acid modification|positive regulation of posttranslational modification Any process that activates or increases the frequency, rate or extent of post-translational protein modification. GO:1901876 regulation of calcium ion binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901876 regulation of calcium ion storage activity Any process that modulates the frequency, rate or extent of calcium ion binding. GO:1901873 regulation of post-translational protein modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901873 regulation of PTM|regulation of posttranslational modification|regulation of posttranslational protein modification|regulation of posttranslational amino acid modification|regulation of post-translational amino acid modification|regulation of post-translational modification Any process that modulates the frequency, rate or extent of post-translational protein modification. GO:0045389 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045389 GO:1901874 negative regulation of post-translational protein modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901874 downregulation of post-translational modification|down regulation of PTM|inhibition of post-translational amino acid modification|downregulation of posttranslational modification|downregulation of post-translational protein modification|downregulation of PTM|downregulation of posttranslational protein modification|down regulation of posttranslational modification|inhibition of posttranslational amino acid modification|down-regulation of post-translational modification|negative regulation of post-translational modification|down regulation of posttranslational protein modification|down-regulation of post-translational protein modification|down-regulation of PTM|negative regulation of PTM|down-regulation of post-translational amino acid modification|negative regulation of post-translational amino acid modification|inhibition of posttranslational modification|down regulation of posttranslational amino acid modification|inhibition of posttranslational protein modification|inhibition of post-translational protein modification|downregulation of posttranslational amino acid modification|inhibition of post-translational modification|downregulation of post-translational amino acid modification|inhibition of PTM|down-regulation of posttranslational modification|negative regulation of posttranslational modification|down regulation of post-translational amino acid modification|down regulation of post-translational modification|negative regulation of posttranslational amino acid modification|down-regulation of posttranslational amino acid modification|negative regulation of posttranslational protein modification|down-regulation of posttranslational protein modification|down regulation of post-translational protein modification Any process that stops, prevents or reduces the frequency, rate or extent of post-translational protein modification. GO:1901871 ecgonone methyl ester catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901871 ecgonone methyl ester breakdown|ecgonone methyl ester catabolism|ecgonone methyl ester degradation The chemical reactions and pathways resulting in the breakdown of ecgonone methyl ester. GO:0045387 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045387 CHEBI:22450 (6aR,11aS,11bR)-10-acetyl-11-hydroxy-7,7-dimethyl-2,6,6a,7,11a,11b-hexahydro-9H-pyrrolo[1',2':2,3]isoindolo[4,5,6-cd]indol-9-one biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22450 GO:1901872 ecgonone methyl ester biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901872 ecgonone methyl ester anabolism|ecgonone methyl ester synthesis|ecgonone methyl ester formation|ecgonone methyl ester biosynthesis The chemical reactions and pathways resulting in the formation of ecgonone methyl ester. GO:0045388 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045388 GO:0045385 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045385 GO:1901870 ecgonone methyl ester metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901870 ecgonone methyl ester metabolism The chemical reactions and pathways involving ecgonone methyl ester. GO:0045386 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045386 UBERON:0003660 eyelid muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003660 muscle organ of eyelid|blepharon muscle organ|muscle organ of blepharon|eyelid muscle organ A muscle that attaches to an eyelid. GO:0070329 tRNA seleno-modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070329 tRNA base modification to selenouridine The substitution of a selenium atom for a sulfur atom in a ribonucleotide in a tRNA molecule. GO:0070327 thyroid hormone transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070327 triiodothyronine transport|thyroxine transport The directed movement of thyroid hormone into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0070328 triglyceride homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070328 triacylglycerol homeostasis Any process involved in the maintenance of an internal steady state of triglyceride within an organism or cell. GO:0070325 lipoprotein particle receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070325 Interacting selectively and non-covalently with a lipoprotein particle receptor. GO:0070326 very-low-density lipoprotein particle receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070326 apolipoprotein E receptor binding|very-low-density lipoprotein receptor binding|VLDL receptor binding|VLDLR binding Interacting selectively and non-covalently with a very-low-density lipoprotein receptor. GO:0070323 obsolete positive regulation of translation in response to nitrogen starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070323 stimulation of translation in response to nitrogen starvation|up-regulation of translation in response to nitrogen starvation|activation of translation in response to nitrogen starvation|up regulation of translation in response to nitrogen starvation|upregulation of translation in response to nitrogen starvation OBSOLETE. Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating deprivation of nitrogen. UBERON:0003665 post-anal tail muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003665 tail muscle|muscle organ of post-vent region|muscle organ of tail|caudal muscle|tail muscle organ|post-vent region muscle organ A muscle organ that attaches to a tail vertebra [Automatically generated definition]. GO:0070324 thyroid hormone binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0070324 triiodothyronine binding|thyroxine binding Interacting selectively and non-covalently with thyroxine (T4) or triiodothyronine (T3), tyrosine-based hormones produced by the thyroid gland. GO:0070321 obsolete regulation of translation in response to nitrogen starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070321 OBSOLETE. Any process that modulates the frequency, rate or extent of the frequency, rate or extent of translation as a result of a stimulus indicating deprivation of nitrogen. UBERON:0003663 hindlimb muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003663 hindlimb muscle organ|muscle organ of hindlimb|muscle organ of inferior member|muscle organ of hind limb|muscle of posterior limb|free lower limb muscle|lower extremity muscle organ|muscle organ of lower extremity|muscle of free lower limb|lower limb skeletal muscle|hind limb muscle organ|inferior member muscle organ Any muscle organ that is part of a hindlimb [Automatically generated definition]. UBERON:0003664 manual digit muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003664 muscle organ of digit of terminal segment of free upper limb|digitus manus muscle organ|digit of hand muscle organ|hand digit muscle|muscle organ of digit of hand|finger muscle organ|muscle organ of digitus manus|hand digit muscle|muscle organ of finger|muscle organ of terminal segment of free upper limb digit|fore limb digit muscle|digit of terminal segment of free upper limb muscle organ|terminal segment of free upper limb digit muscle organ|muscle organ of hand digit|hand digit muscle organ Any muscle organ that is part of a finger [Automatically generated definition]. GO:0070322 obsolete negative regulation of translation in response to nitrogen starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070322 down-regulation of translation in response to nitrogen starvation|downregulation of translation in response to nitrogen starvation|down regulation of translation in response to nitrogen starvation|inhibition of translation in response to nitrogen starvation OBSOLETE. Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating deprivation of nitrogen. UBERON:0003661 limb muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003661 muscle organ of limb|limb muscle organ|limb skeletal muscle Any muscle organ that is part of a limb [Automatically generated definition]. UBERON:0003662 forelimb muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003662 musculature of the arm|arm muscle system|forelimb muscle organ|free upper limb muscle|fore limb muscle organ|wing muscle|muscle of free upper limb|muscle of upper limb|musculature of arm|upper limb skeletal muscle Any muscle organ that is part of a forelimb. GO:0070320 inward rectifier potassium channel inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070320 Stops, prevents, or reduces the activity of an inwardly rectifying potassium channel. GO:0070350 regulation of white fat cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070350 regulation of white adipocyte proliferation|regulation of white adipose cell proliferation Any process that modulates the frequency, rate or extent of white fat cell proliferation. GO:0045394 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045394 GO:0045395 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045395 GO:0070351 negative regulation of white fat cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070351 down-regulation of white fat cell proliferation|negative regulation of white adipose cell proliferation|downregulation of white fat cell proliferation|negative regulation of white adipocyte proliferation|down regulation of white fat cell proliferation|inhibition of white fat cell proliferation Any process that stops or decreases the rate or extent of white fat cell proliferation. GO:0045392 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045392 GO:0045393 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045393 GO:0045390 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045390 GO:0045391 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045391 GO:1901888 regulation of cell junction assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901888 Any process that modulates the frequency, rate or extent of cell junction assembly. CHEBI:22423 alpha-L-fucosyl-(1->2)-D-galactose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_22423 GO:1901889 negative regulation of cell junction assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901889 down regulation of cell junction assembly|inhibition of cell junction assembly|down-regulation of cell junction assembly|downregulation of cell junction assembly Any process that stops, prevents or reduces the frequency, rate or extent of cell junction assembly. GO:1901886 2-hydroxybenzoyl-CoA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901886 2-hydroxybenzoyl-CoA breakdown|2-hydroxybenzoyl-CoA degradation|2-hydroxybenzoyl-CoA catabolism The chemical reactions and pathways resulting in the breakdown of 2-hydroxybenzoyl-CoA. GO:1901887 2-hydroxybenzoyl-CoA biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901887 2-hydroxybenzoyl-CoA biosynthesis|2-hydroxybenzoyl-CoA anabolism|2-hydroxybenzoyl-CoA synthesis|2-hydroxybenzoyl-CoA formation The chemical reactions and pathways resulting in the formation of 2-hydroxybenzoyl-CoA. GO:1901884 4-hydroxycoumarin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901884 4-hydroxycoumarin synthesis|4-hydroxycoumarin formation|4-hydroxycoumarin biosynthesis|4-hydroxycoumarin anabolism The chemical reactions and pathways resulting in the formation of 4-hydroxycoumarin. OBO:GOCHE_76815 substance with EC 2.7.7.* (nucleotidyltransferase) inhibitor role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_76815 GO:1901885 2-hydroxybenzoyl-CoA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901885 2-hydroxybenzoyl-CoA metabolism The chemical reactions and pathways involving 2-hydroxybenzoyl-CoA. GO:1901882 4-hydroxycoumarin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901882 4-hydroxycoumarin metabolism The chemical reactions and pathways involving 4-hydroxycoumarin. GO:0045398 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045398 GO:0045399 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045399 GO:1901883 4-hydroxycoumarin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901883 4-hydroxycoumarin catabolism|4-hydroxycoumarin degradation|4-hydroxycoumarin breakdown The chemical reactions and pathways resulting in the breakdown of 4-hydroxycoumarin. GO:1901880 negative regulation of protein depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901880 inhibition of protein polymer catabolic process|inhibition of protein depolymerization|downregulation of protein polymer degradation|down regulation of protein polymer breakdown|downregulation of protein polymer breakdown|down regulation of protein polymer catabolic process|down-regulation of protein polymer catabolism|negative regulation of protein polymer catabolism|down-regulation of protein polymer degradation|negative regulation of protein polymer degradation|downregulation of protein polymer catabolic process|down-regulation of protein polymer breakdown|negative regulation of protein polymer breakdown|downregulation of protein polymer catabolism|down-regulation of protein depolymerization|negative regulation of protein polymer catabolic process|down-regulation of protein polymer catabolic process|down regulation of protein polymer catabolism|inhibition of protein polymer degradation|downregulation of protein depolymerization|inhibition of protein polymer catabolism|inhibition of protein polymer breakdown|down regulation of protein polymer degradation|down regulation of protein depolymerization Any process that stops, prevents or reduces the frequency, rate or extent of protein depolymerization. GO:0045396 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045396 GO:1901881 positive regulation of protein depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901881 upregulation of protein polymer breakdown|up-regulation of protein polymer catabolism|upregulation of protein depolymerization|upregulation of protein polymer catabolic process|up regulation of protein polymer degradation|positive regulation of protein polymer degradation|activation of protein polymer catabolism|up regulation of protein polymer breakdown|up-regulation of protein depolymerization|activation of protein depolymerization|activation of protein polymer degradation|positive regulation of protein polymer catabolism|positive regulation of protein polymer breakdown|up regulation of protein polymer catabolic process|up regulation of protein polymer catabolism|positive regulation of protein polymer catabolic process|activation of protein polymer breakdown|up-regulation of protein polymer degradation|activation of protein polymer catabolic process|up-regulation of protein polymer breakdown|up regulation of protein depolymerization|upregulation of protein polymer catabolism|up-regulation of protein polymer catabolic process|upregulation of protein polymer degradation Any process that activates or increases the frequency, rate or extent of protein depolymerization. GO:0045397 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045397 GO:1901890 positive regulation of cell junction assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901890 up regulation of cell junction assembly|upregulation of cell junction assembly|up-regulation of cell junction assembly|activation of cell junction assembly Any process that activates or increases the frequency, rate or extent of cell junction assembly. GO:0070358 actin polymerization-dependent cell motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070358 cell motility by actin tail formation A process involved in the controlled movement of a bacterial cell powered by the continuous polymerization of actin at one pole of the cell. GO:0070359 actin polymerization-dependent cell motility involved in migration of symbiont in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070359 actin polymerization-dependent cell motility involved in migration of symbiont within host A process involved in the controlled movement of a bacterial cell within a host cell, powered by the continuous polymerization of host actin at one pole of the cell. GO:0070356 synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Rab3a complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070356 STX1a-STX1b-SNAP25-RAB3a-SYT1-VAMP2 complex|SNARE complex (STX1a, STX1b, SNAP25, RAB3a, SYT1, VAMP2) A SNARE complex that contains synaptotagmin, synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, syntaxin1b, and Rab3a (or orthologs thereof). GO:0070357 alphav-beta3 integrin-CD47 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070357 ITGB3-ITGAV-CD47 complex A protein complex that consists of an alphav-beta3 integrin complex bound to CD47 (also known as IAP). GO:0070354 GATA2-TAL1-TCF3-Lmo2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070354 A protein complex that contains the zinc finger transcription factor GATA2, the LIM domain protein Lmo2 (RBTN2), the basic helix-loop-helix protein TAL1 and its binding partner TCF3. The complex is involved transcriptional regulation in hematopoiesis. GO:0070355 synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Rab3a-complexin II complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070355 STX1a-STX1b-SNAP25-RAB3a-SYT1-VAMP2-CPLX2 complex|SNARE complex (STX1a, STX1b, SNAP25, RAB3a, SYT1, VAMP2, CPLX2) A SNARE complex that contains synaptotagmin, synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, syntaxin1b, Rab3a, and complexin II (or orthologs thereof). GO:0070352 positive regulation of white fat cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070352 stimulation of white fat cell proliferation|up-regulation of white fat cell proliferation|activation of white fat cell proliferation|positive regulation of white adipose cell proliferation|up regulation of white fat cell proliferation|positive regulation of white adipocyte proliferation|upregulation of white fat cell proliferation Any process that activates or increases the rate or extent of white fat cell proliferation. GO:0070353 GATA1-TAL1-TCF3-Lmo2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070353 A protein complex that contains the zinc finger transcription factor GATA1, the LIM domain protein Lmo2 (RBTN2), the basic helix-loop-helix protein TAL1 and its binding partner TCF3. The complex is involved transcriptional regulation in hematopoiesis. GO:0070340 detection of bacterial lipopeptide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070340 The series of events in which a bacterial lipopeptide stimulus is received by a cell and converted into a molecular signal. GO:1901899 positive regulation of relaxation of cardiac muscle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901899 upregulation of relaxation of cardiac muscle|up-regulation of relaxation of cardiac muscle|activation of relaxation of cardiac muscle|up regulation of relaxation of cardiac muscle Any process that activates or increases the frequency, rate or extent of relaxation of cardiac muscle. GO:1901897 regulation of relaxation of cardiac muscle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901897 Any process that modulates the frequency, rate or extent of relaxation of cardiac muscle. GO:1901898 negative regulation of relaxation of cardiac muscle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901898 down regulation of relaxation of cardiac muscle|inhibition of relaxation of cardiac muscle|down-regulation of relaxation of cardiac muscle|downregulation of relaxation of cardiac muscle Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of cardiac muscle. GO:1901895 negative regulation of ATPase-coupled calcium transmembrane transporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901895 downregulation of calcium ABC transporter|downregulation of calcium-translocating P-type ATPase activity|downregulation of sarcoplasmic reticulum ATPase|inhibition of calcium efflux ATPase|downregulation of Ca2+-transporting ATPase activity|down regulation of ATP phosphohydrolase (Ca2+-transporting)|downregulation of Ca2+-pumping ATPase activity|inhibition of plasma membrane Ca-ATPase|down-regulation of calcium-transporting ATPase activity|inhibition of calcium transporting ATPase activity|down regulation of calcium-translocating P-type ATPase activity|negative regulation of calcium pump|inhibition of Ca(2+)-transporting ATPase activity|down-regulation of calcium pump|down regulation of Ca2+-pumping ATPase activity|downregulation of sarco(endo)plasmic reticulum Ca2+-ATPase|down regulation of calcium efflux ATPase|negative regulation of calcium ABC transporter|inhibition of ATP phosphohydrolase (Ca2+-transporting)|down-regulation of calcium ABC transporter|down-regulation of sarcoplasmic reticulum ATPase|negative regulation of sarcoplasmic reticulum ATPase|negative regulation of Ca2+-transporting ATPase activity|down-regulation of Ca2+-transporting ATPase activity|down regulation of plasma membrane Ca-ATPase|inhibition of calcium-translocating P-type ATPase activity|downregulation of calcium efflux ATPase|down regulation of Ca(2+)-transporting ATPase activity|downregulation of calcium-transporting ATPase activity|down regulation of sarco(endo)plasmic reticulum Ca2+-ATPase|inhibition of Ca2+-pumping ATPase activity|downregulation of calcium pump|downregulation of plasma membrane Ca-ATPase|negative regulation of calcium transporting ATPase activity|down-regulation of calcium transporting ATPase activity|downregulation of Ca(2+)-transporting ATPase activity|down regulation of calcium-transporting ATPase activity|down regulation of calcium pump|inhibition of calcium-transporting ATPase activity|inhibition of sarco(endo)plasmic reticulum Ca2+-ATPase|negative regulation of calcium-transporting ATPase activity|down-regulation of ATP phosphohydrolase (Ca2+-transporting)|down-regulation of calcium efflux ATPase|inhibition of calcium ABC transporter|negative regulation of ATP phosphohydrolase (Ca2+-transporting)|negative regulation of calcium efflux ATPase|inhibition of Ca2+-transporting ATPase activity|inhibition of sarcoplasmic reticulum ATPase|negative regulation of calcium-translocating P-type ATPase activity|negative regulation of plasma membrane Ca-ATPase|down-regulation of calcium-translocating P-type ATPase activity|down-regulation of plasma membrane Ca-ATPase|down-regulation of Ca(2+)-transporting ATPase activity|downregulation of calcium transporting ATPase activity|negative regulation of Ca2+-pumping ATPase activity|negative regulation of Ca(2+)-transporting ATPase activity|down-regulation of Ca2+-pumping ATPase activity|inhibition of calcium pump|down regulation of calcium ABC transporter|down regulation of sarcoplasmic reticulum ATPase|down regulation of Ca2+-transporting ATPase activity|down regulation of calcium transporting ATPase activity|downregulation of ATP phosphohydrolase (Ca2+-transporting)|down-regulation of sarco(endo)plasmic reticulum Ca2+-ATPase|negative regulation of sarco(endo)plasmic reticulum Ca2+-ATPase Any process that stops, prevents or reduces the frequency, rate or extent of an ATPase-coupled calcium transmembrane transporter activity. GO:1901896 positive regulation of ATPase-coupled calcium transmembrane transporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901896 up regulation of Ca2+-pumping ATPase activity|upregulation of calcium transporting ATPase activity|up-regulation of Ca(2+)-transporting ATPase activity|up regulation of calcium ABC transporter|positive regulation of sarco(endo)plasmic reticulum Ca2+-ATPase|up regulation of sarcoplasmic reticulum ATPase|positive regulation of calcium ABC transporter|up regulation of Ca2+-transporting ATPase activity|upregulation of calcium efflux ATPase|up regulation of sarco(endo)plasmic reticulum Ca2+-ATPase|activation of calcium pump|upregulation of ATP phosphohydrolase (Ca2+-transporting)|positive regulation of sarcoplasmic reticulum ATPase|upregulation of calcium-translocating P-type ATPase activity|positive regulation of Ca2+-transporting ATPase activity|upregulation of plasma membrane Ca-ATPase|upregulation of Ca2+-pumping ATPase activity|activation of calcium ABC transporter|up-regulation of calcium transporting ATPase activity|upregulation of Ca(2+)-transporting ATPase activity|up regulation of calcium-transporting ATPase activity|positive regulation of calcium pump|activation of sarcoplasmic reticulum ATPase|up regulation of calcium pump|activation of Ca2+-transporting ATPase activity|upregulation of sarco(endo)plasmic reticulum Ca2+-ATPase|up-regulation of ATP phosphohydrolase (Ca2+-transporting)|up regulation of calcium efflux ATPase|up-regulation of calcium ABC transporter|activation of calcium transporting ATPase activity|up-regulation of calcium-translocating P-type ATPase activity|up-regulation of sarcoplasmic reticulum ATPase|up regulation of plasma membrane Ca-ATPase|positive regulation of calcium efflux ATPase|up-regulation of Ca2+-transporting ATPase activity|positive regulation of plasma membrane Ca-ATPase|up-regulation of Ca2+-pumping ATPase activity|upregulation of calcium-transporting ATPase activity|up regulation of Ca(2+)-transporting ATPase activity|activation of ATP phosphohydrolase (Ca2+-transporting)|positive regulation of calcium transporting ATPase activity|activation of calcium efflux ATPase|activation of calcium-translocating P-type ATPase activity|positive regulation of Ca(2+)-transporting ATPase activity|upregulation of calcium pump|up regulation of calcium transporting ATPase activity|up-regulation of sarco(endo)plasmic reticulum Ca2+-ATPase|activation of plasma membrane Ca-ATPase|activation of Ca2+-pumping ATPase activity|upregulation of calcium ABC transporter|positive regulation of calcium-transporting ATPase activity|upregulation of sarcoplasmic reticulum ATPase|positive regulation of ATP phosphohydrolase (Ca2+-transporting)|activation of Ca(2+)-transporting ATPase activity|upregulation of Ca2+-transporting ATPase activity|positive regulation of calcium-translocating P-type ATPase activity|up-regulation of calcium efflux ATPase|up regulation of ATP phosphohydrolase (Ca2+-transporting)|activation of calcium-transporting ATPase activity|up-regulation of calcium-transporting ATPase activity|up regulation of calcium-translocating P-type ATPase activity|activation of sarco(endo)plasmic reticulum Ca2+-ATPase|up-regulation of plasma membrane Ca-ATPase|positive regulation of Ca2+-pumping ATPase activity|up-regulation of calcium pump Any process that activates or increases the frequency, rate or extent of an ATPase-coupled calcium transmembrane transporter activity. GO:1901893 positive regulation of cell septum assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901893 up regulation of cell septum assembly|upregulation of cell septum assembly|up-regulation of cell septum assembly|activation of cell septum assembly Any process that activates or increases the frequency, rate or extent of cell septum assembly. GO:1901894 regulation of ATPase-coupled calcium transmembrane transporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901894 regulation of ATP phosphohydrolase (Ca2+-transporting)|regulation of calcium-translocating P-type ATPase activity|regulation of Ca2+-pumping ATPase activity|regulation of sarco(endo)plasmic reticulum Ca2+-ATPase|regulation of calcium efflux ATPase|regulation of plasma membrane Ca-ATPase|regulation of Ca(2+)-transporting ATPase activity|regulation of calcium pump|regulation of calcium transporting ATPase activity|regulation of calcium ABC transporter|regulation of sarcoplasmic reticulum ATPase|regulation of calcium-transporting ATPase activity|regulation of Ca2+-transporting ATPase activity Any process that modulates the frequency, rate or extent of an ATPase-coupled calcium transmembrane transporter activity. GO:1901891 regulation of cell septum assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901891 Any process that modulates the frequency, rate or extent of cell septum assembly. GO:1901892 negative regulation of cell septum assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1901892 downregulation of cell septum assembly|down regulation of cell septum assembly|inhibition of cell septum assembly|down-regulation of cell septum assembly Any process that stops, prevents or reduces the frequency, rate or extent of cell septum assembly. GO:0070349 positive regulation of brown fat cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070349 stimulation of brown fat cell proliferation|up-regulation of brown fat cell proliferation|activation of brown fat cell proliferation|positive regulation of brown adipose cell proliferation|up regulation of brown fat cell proliferation|positive regulation of brown adipocyte proliferation|upregulation of brown fat cell proliferation Any process that activates or increases the rate or extent of brown fat cell proliferation. GO:0070347 regulation of brown fat cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070347 regulation of brown adipocyte proliferation|regulation of brown adipose cell proliferation Any process that modulates the frequency, rate or extent of brown fat cell proliferation. GO:0070348 negative regulation of brown fat cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070348 down-regulation of brown fat cell proliferation|negative regulation of brown adipose cell proliferation|downregulation of brown fat cell proliferation|down regulation of brown fat cell proliferation|inhibition of brown fat cell proliferation|negative regulation of brown adipocyte proliferation Any process that stops or decreases the rate or extent of brown fat cell proliferation. GO:0070345 negative regulation of fat cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070345 downregulation of fat cell proliferation|down regulation of fat cell proliferation|inhibition of fat cell proliferation|negative regulation of adipocyte proliferation|down-regulation of fat cell proliferation|negative regulation of adipose cell proliferation Any process that stops or decreases the rate or extent of fat cell proliferation. GO:0070346 positive regulation of fat cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070346 upregulation of fat cell proliferation|stimulation of fat cell proliferation|positive regulation of adipocyte proliferation|up-regulation of fat cell proliferation|activation of fat cell proliferation|positive regulation of adipose cell proliferation|up regulation of fat cell proliferation Any process that activates or increases the rate or extent of fat cell proliferation. GO:0070343 white fat cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070343 white adipocyte proliferation|white adipose cell proliferation The multiplication or reproduction of white fat cells by cell division, resulting in the expansion of their population. GO:0070344 regulation of fat cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070344 regulation of adipose cell proliferation|regulation of adipocyte proliferation Any process that modulates the frequency, rate or extent of fat cell proliferation. GO:0070341 fat cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070341 adipocyte proliferation|adipose cell proliferation The multiplication or reproduction of fat cells by cell division, resulting in the expansion of their population. A fat cell is an animal connective tissue cell specialized for the synthesis and storage of fat. GO:0070342 brown fat cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070342 brown adipose cell proliferation|brown adipocyte proliferation The multiplication or reproduction of brown fat cells by cell division, resulting in the expansion of their population. A brown fat cell is a fat cell found the thermogenic form of adipose tissue found in newborns of many species. GO:0070372 regulation of ERK1 and ERK2 cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070372 regulation of ERK2 cascade|regulation of ERK1 cascade|regulation of ERK1 and ERK2 signalling pathway|regulation of ERK1/2 cascade|regulation of ERK cascade|regulation of MAPK3 cascade|regulation of ERK1 and ERK2 signaling pathway|regulation of MAPK1 cascade Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade. GO:0070373 negative regulation of ERK1 and ERK2 cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070373 negative regulation of MAPK3 cascade|negative regulation of MAPK1 cascade|negative regulation of ERK1 and ERK2 signaling pathway|down regulation of ERK1 and ERK2 cascade|downregulation of ERK1 and ERK2 cascade|down-regulation of ERK1 and ERK2 cascade|negative regulation of ERK2 cascade|negative regulation of ERK1 cascade|negative regulation of ERK cascade|negative regulation of ERK1 and ERK2 signalling pathway|negative regulation of ERK1/2 cascade|inhibition of ERK1 and ERK2 cascade Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade. GO:0070370 cellular heat acclimation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070370 cellular thermotolerance Any process that increases heat tolerance of a cell in response to high temperatures. GO:0070371 ERK1 and ERK2 cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070371 MAPK3 cascade|MAPK1 cascade|ERK1 and ERK2 signaling pathway|extracellular signal-regulated kinase 1/2 cascade|ERK2 cascade|ERK1 cascade|ERK1 and ERK2 signalling pathway|extracellular signal-regulated kinase 1/2 (ERK1/2) cascade|ERK1/2 cascade|ERK cascade An intracellular protein kinase cascade containing at least ERK1 or ERK2 (MAPKs), a MEK (a MAPKK) and a MAP3K. The cascade may involve 4 different kinases, as it can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell. GO:0070378 positive regulation of ERK5 cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070378 positive regulation of MAPK7 cascade|positive regulation of BMK cascade|positive regulation of BMK1 cascade|up-regulation of BMK cascade|positive regulation of BMK signaling pathway|upregulation of BMK cascade|positive regulation of BMK signalling pathway|positive regulation of ERK5 signaling pathway|up regulation of BMK cascade|activation of BMK cascade|stimulation of BMK cascade Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK5 cascade. GO:0070379 high mobility group box 1 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070379 HMGB1 binding Interacting selectively and non-covalently with high mobility group box 1 (HMBGB1). GO:0070376 regulation of ERK5 cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070376 regulation of BMK signaling pathway|regulation of BMK1 cascade|regulation of MAPK7 cascade|regulation of BMK cascade|regulation of ERK5 signaling pathway|regulation of BMK signalling pathway Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK5 cascade. GO:0070377 negative regulation of ERK5 cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070377 negative regulation of MAPK7 cascade|negative regulation of BMK cascade|inhibition of BMK cascade|negative regulation of BMK signaling pathway|negative regulation of ERK5 signaling pathway|negative regulation of BMK signalling pathway|down regulation of BMK cascade|downregulation of BMK cascade|down-regulation of BMK cascade|negative regulation of BMK1 cascade Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK5 cascade. GO:0070374 positive regulation of ERK1 and ERK2 cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070374 positive regulation of MAPK1 cascade|positive regulation of ERK1 and ERK2 signaling pathway|upregulation of ERK1 and ERK2 cascade|up regulation of ERK1 and ERK2 cascade|activation of ERK1 and ERK2 cascade|stimulation of ERK1 and ERK2 cascade|positive regulation of ERK cascade|positive regulation of ERK2 cascade|positive regulation of ERK1 cascade|up-regulation of ERK1 and ERK2 cascade|positive regulation of ERK1 and ERK2 signalling pathway|positive regulation of ERK1/2 cascade|positive regulation of MAPK3 cascade Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade. GO:0070375 ERK5 cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070375 MAPK7 cascade|big MAP kinase signaling cascade|BMK cascade|ERK5 signaling pathway|BMK signalling pathway|extracellular signal-regulated kinase 5 cascade|BMK signaling pathway|BMK1 cascade An intracellular protein kinase cascade containing at least ERK5 (also called BMK1; a MAPK), a MEK (a MAPKK) and a MAP3K. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell. GO:0070361 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0070361 GO:0070362 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0070362 GO:0070360 migration of symbiont within host by polymerization of host actin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070360 The directional movement of an organism, usually a bacterial cell, from one place to another within its host organism, by a process involving continuous polymerization of host actin at one pole of the symbiont cell. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0070369 beta-catenin-TCF7L2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070369 beta-catenin-TCF4 complex A protein complex that contains beta-catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription. GO:0070367 negative regulation of hepatocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070367 down regulation of hepatocyte differentiation|inhibition of hepatocyte differentiation|negative regulation of liver cell differentiation|down-regulation of hepatocyte differentiation|downregulation of hepatocyte differentiation Any process that stops or decreases the rate or extent of hepatocyte differentiation. GO:0070368 positive regulation of hepatocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070368 upregulation of hepatocyte differentiation|stimulation of hepatocyte differentiation|up-regulation of hepatocyte differentiation|activation of hepatocyte differentiation|positive regulation of liver cell differentiation|up regulation of hepatocyte differentiation Any process that activates or increases the rate or extent of hepatocyte differentiation. GO:0070365 hepatocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070365 liver cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a hepatocyte. A hepatocyte is specialized epithelial cell that is organized into interconnected plates called lobules, and is the main structural component of the liver. GO:0070366 regulation of hepatocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070366 regulation of liver cell differentiation Any process that modulates the frequency, rate or extent of hepatocyte differentiation. GO:0070363 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0070363 GO:0070364 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0070364 CHEBI:46398 UTP(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46398 CHEBI:71354 norsolorinic acid anthrone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71354 CHEBI:71355 beta-D-GlcpNAc-(1->3)-beta-D-Galp-(1->4)-beta-D-GlcpNAc biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71355 CHEBI:71356 norsolorinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71356 GO:0021540 corpus callosum morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021540 The process in which the anatomical structures of the corpus callosum are generated and organized. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provides communications between the right and left cerebral hemispheres. GO:0021541 ammon gyrus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021541 cornu ammonis development|Ammon's horn development The process whose specific outcome is the progression of the ammon gyrus over time, from its formation to the mature structure. The ammon gyrus, often subdivided into the CA1 and CA3 regions, is one of the two interlocking gyri of the hippocampus that is rich in large pyramidal neurons. CHEBI:71358 UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-N(6)-(L-alanyl)-L-lysyl-D-alanyl-D-alaninate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71358 GO:0021542 dentate gyrus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021542 The process whose specific outcome is the progression of the dentate gyrus over time, from its formation to the mature structure. The dentate gyrus is one of two interlocking gyri of the hippocampus. It contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus. GO:0021543 pallium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021543 The process whose specific outcome is the progression of the pallium over time, from its formation to the mature structure. The pallium is the roof region of the telencephalon. GO:0021544 subpallium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021544 The process whose specific outcome is the progression of the subpallium over time, from its formation to the mature structure. The subpallium is the base region of the telencephalon. GO:0045512 interleukin-26 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045512 IL-26 binding Interacting selectively and non-covalently with interleukin-26. GO:0045513 interleukin-27 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045513 IL-27 binding Interacting selectively and non-covalently with interleukin-27. GO:0045510 interleukin-24 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045510 IL-24 binding Interacting selectively and non-covalently with interleukin-24. GO:0045511 interleukin-25 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045511 IL-25 binding Interacting selectively and non-covalently with interleukin-25. GO:0045518 interleukin-22 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045518 interleukin-22 receptor ligand|IL-22 Interacting selectively and non-covalently with the interleukin-22 receptor. GO:0045519 interleukin-23 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045519 interleukin-23 receptor ligand|IL-23 Interacting selectively and non-covalently with the interleukin-23 receptor. GO:0045516 interleukin-19 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045516 interleukin-19 receptor ligand|IL-19 Interacting selectively and non-covalently with the interleukin-19 receptor. GO:0045517 interleukin-20 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045517 interleukin-20 receptor ligand|IL-20 Interacting selectively and non-covalently with the interleukin-20 receptor. GO:0045514 interleukin-16 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045514 interleukin-16 receptor ligand|IL-16 Interacting selectively and non-covalently with the interleukin-16 receptor. GO:0045515 interleukin-18 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045515 interleukin-18 receptor ligand|IL-18 Interacting selectively and non-covalently with the interleukin-18 receptor. GO:0021545 cranial nerve development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021545 The process whose specific outcome is the progression of the cranial nerves over time, from its formation to the mature structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. GO:0021546 rhombomere development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021546 The process whose specific outcome is the progression of the rhombomere over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. GO:0021547 midbrain-hindbrain boundary initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021547 MHB biosynthesis|midbrain-hindbrain boundary biosynthesis|midbrain-hindbrain boundary formation|isthmus biosynthesis|isthmus formation|MHB formation The regionalization process that gives rise to the midbrain-hindbrain boundary. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate. GO:0021548 pons development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021548 The process whose specific outcome is the progression of the pons over time, from its formation to the mature structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum. GO:0021549 cerebellum development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021549 The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills. CHEBI:71352 L-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71352 CHEBI:71353 Mo(VI)-molybdopterin cytosine dinucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71353 CHEBI:71365 rifampicin zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71365 GO:0021530 spinal cord oligodendrocyte cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021530 The process in which a cell becomes capable of differentiating autonomously into an oligodendrocyte in an environment that is neutral with respect to the developmental pathway. GO:0021531 spinal cord radial glial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021531 radial glial cell differentiation in spinal cord The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of radial glial cells. Radial cell precursors differentiate into both neuronal cell types and mature radial glial cells. Mature radial glial cells regulate the axon growth and pathfinding processes that occur during white matter patterning of the developing spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate. GO:0021532 neural tube patterning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021532 The regionalization process that regulates the coordinated growth that establishes the non-random spatial arrangement of the neural tube. GO:0021533 cell differentiation in hindbrain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021533 The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate. GO:0045523 interleukin-27 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045523 interleukin-27 receptor ligand|IL-27 Interacting selectively and non-covalently with the interleukin-27 receptor. GO:0045524 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045524 GO:0045521 interleukin-25 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045521 interleukin-25 receptor ligand|IL-25 Interacting selectively and non-covalently with the interleukin-25 receptor. GO:0045522 interleukin-26 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045522 interleukin-26 receptor ligand|IL-26 Interacting selectively and non-covalently with the interleukin-26 receptor. GO:0045520 interleukin-24 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045520 interleukin-24 receptor ligand|IL-24 Interacting selectively and non-covalently with the interleukin-24 receptor. GO:0045529 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045529 GO:0045527 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045527 GO:0045528 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045528 GO:0045525 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045525 GO:0045526 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045526 GO:0021534 cell proliferation in hindbrain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021534 The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain. GO:0021535 cell migration in hindbrain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021535 The orderly movement of a cell that will reside in the hindbrain. GO:0021536 diencephalon development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021536 The process whose specific outcome is the progression of the diencephalon over time, from its formation to the mature structure. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex. GO:0021537 telencephalon development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021537 cerebrum development The process whose specific outcome is the progression of the telencephalon over time, from its formation to the mature structure. The telencephalon is the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived. CHEBI:71361 8-oxo-dAMP(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71361 GO:0021538 epithalamus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021538 The progression of the epithalamus over time from its initial formation until its mature state. The epithalamus is the small dorsomedial area of the thalamus including the habenular nuclei and associated fiber bundles, the pineal body, and the epithelial roof of the third ventricle. CHEBI:71362 8-oxo-dADP(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71362 GO:0021539 subthalamus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021539 ventral thalamus development The process whose specific outcome is the progression of the subthalamus over time, from its formation to the mature structure. The subthalamus is the anterior part of the diencephalon that lies between the thalamus, hypothalamus, and tegmentum of the mesencephalon, including subthalamic nucleus, zona incerta, the fields of Forel, and the nucleus of ansa lenticularis. CHEBI:71363 2-oxo-dADP(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71363 GO:0021520 spinal cord motor neuron cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021520 The process in which a cell becomes capable of differentiating autonomously into a motor neuron in an environment that is neutral with respect to the developmental pathway. GO:0021521 ventral spinal cord interneuron specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021521 The process in which a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron in an environment that is neutral with respect to the developmental pathway. GO:0021522 spinal cord motor neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021522 The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of motor neurons. Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate. GO:0045534 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045534 GO:0045535 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045535 GO:0045532 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045532 GO:0045533 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045533 GO:0045530 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045530 GO:0045531 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045531 GO:0045538 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045538 GO:0045539 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045539 GO:0045536 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045536 GO:0045537 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045537 GO:0021523 somatic motor neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021523 The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of somatic motor neurons. Somatic motor neurons innervate skeletal muscle targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate. GO:0021524 visceral motor neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021524 The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of visceral motor neurons. Visceral motor neurons innervate glandular targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate. GO:0021525 lateral motor column neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021525 The process in which differentiating motor neurons in the neural tube acquire the specialized structural and/or functional features of lateral motor column neurons. Lateral motor column neurons are generated only on limb levels and send axons into the limb mesenchyme. Differentiation includes the processes involved in commitment of a cell to a specific fate. GO:0021526 medial motor column neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021526 The process in which differentiating motor neurons in the neural tube acquire the specialized structural and/or functional features of medial motor column neurons. Medial motor column neurons are generated at all rostrocaudal levels and send axons to the axial muscles (medial group) and to the body wall muscles (lateral group). Differentiation includes the processes involved in commitment of a cell to a specific fate. GO:0021527 spinal cord association neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021527 spinal cord dorsal interneuron differentiation The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of association neurons. Association neurons are cells located in the dorsal portion of the spinal cord that integrate sensory input. Differentiation includes the processes involved in commitment of a cell to a specific fate. GO:0021528 commissural neuron differentiation in spinal cord biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021528 The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of commissural neurons. Commissural neurons in both vertebrates and invertebrates transfer information from one side of their bodies to the other through the midline. Differentiation includes the processes involved in commitment of a cell to a specific fate. GO:0021529 spinal cord oligodendrocyte cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021529 The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of oligodendrocytes. Oligodendrocytes are non-neuronal cells. The primary function of oligodendrocytes is the myelination of nerve axons in the central nervous system. Differentiation includes the processes involved in commitment of a cell to a specific fate. GO:0021510 spinal cord development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021510 The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues. GO:0021511 spinal cord patterning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021511 The regionalization process that regulates the coordinated growth and establishes the non-random spatial arrangement of the spinal cord. GO:0045545 syndecan binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045545 Interacting selectively and non-covalently with syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells. GO:0045546 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045546 GO:0045543 gibberellin 2-beta-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045543 RHEA:15005|MetaCyc:PWY-102|EC:1.14.11.13 (gibberellin-1),2-oxoglutarate:oxygen oxidoreductase (2beta-hydroxylating)|gibberellin 2-beta-hydroxylase activity|gibberellin 2beta-dioxygenase activity|gibberellin 2-oxidase activity|gibberellin 2beta-hydroxylase activity Catalysis of the reaction: a gibberellin + 2-oxoglutarate + O2 = a 2-beta-hydroxygibberellin + succinate + CO2. GO:0045544 gibberellin 20-oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045544 Catalysis of the oxidation of C-20 gibberellins to form the corresponding C-19 lactones. GO:0045541 negative regulation of cholesterol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045541 negative regulation of cholesterol anabolism|negative regulation of cholesterol synthesis|negative regulation of cholesterol formation|negative regulation of cholesterol biosynthesis|down-regulation of cholesterol biosynthetic process|downregulation of cholesterol biosynthetic process|down regulation of cholesterol biosynthetic process|inhibition of cholesterol biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol. GO:0045542 positive regulation of cholesterol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045542 positive regulation of cholesterol synthesis|stimulation of cholesterol biosynthetic process|positive regulation of cholesterol formation|up-regulation of cholesterol biosynthetic process|activation of cholesterol biosynthetic process|positive regulation of cholesterol biosynthesis|up regulation of cholesterol biosynthetic process|upregulation of cholesterol biosynthetic process|positive regulation of cholesterol anabolism Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol. GO:0045540 regulation of cholesterol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045540 regulation of cholesterol anabolism|regulation of cholesterol biosynthesis|regulation of cholesterol synthesis|regulation of cholesterol formation Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol. GO:0045549 9-cis-epoxycarotenoid dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045549 EC:1.13.11.51 PvNCED1|NCED|nine-cis-epoxycarotenoid dioxygenase activity|AtNCED3|9-cis-epoxycarotenoid 11,12-dioxygenase activity|VP14|neoxanthin cleavage enzyme Catalysis of the reactions: a 9-cis-epoxycarotenoid + O2 = 2-cis,4-trans-xanthoxin + a 12'-apo-carotenal; 9-cis-violaxanthin + O2 = 2-cis,4-trans-xanthoxin + (3S,5R,6S)-5,6-epoxy-3-hydroxy-5,6-dihydro-12'-apo-beta-caroten-12'-al; and 9'-cis-neoxanthin + O2 = 2-cis,4-trans-xanthoxin + (3S,5R,6R)-5,6-dihydroxy-6,7-didehydro-5,6-dihydro-12'-apo-beta-caroten-12'-al. GO:0045547 dehydrodolichyl diphosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045547 Catalysis of the condensation of isopentenyl diphosphate and farnesyl diphosphate in the cis-configuration to form dehydrodolichyl diphosphate. GO:0045548 phenylalanine ammonia-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045548 RHEA:21384|EC:4.3.1.25|EC:4.3.1.24 phe ammonia-lyase activity|PAL activity|L-phenylalanine ammonia-lyase activity|phenylalanine ammonium-lyase activity|phenylalanine deaminase activity Catalysis of the reaction: L-phenylalanine = NH(4)(+) + trans-cinnamate. GO:0021512 spinal cord anterior/posterior patterning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021512 spinal cord rostrocaudal patterning|spinal cord anterior-posterior patterning The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the spinal cord. GO:0021513 spinal cord dorsal/ventral patterning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021513 spinal cord dorsoventral patterning|spinal cord dorsal-ventral patterning The process that regulates the coordinated growth and differentiation that establishes the non-random dorsal-ventral spatial arrangement of the spinal cord. GO:0021514 ventral spinal cord interneuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021514 The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate. GO:0021515 cell differentiation in spinal cord biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021515 The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate. GO:0021516 dorsal spinal cord development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021516 The process whose specific outcome is the progression of the dorsal region of the spinal cord over time, from its formation to the mature structure. The dorsal region of the mature spinal cord contains neurons that process and relay sensory input. GO:0021517 ventral spinal cord development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021517 The process whose specific outcome is the progression of the ventral region of the spinal cord over time, from its formation to the mature structure. The neurons of the ventral region of the mature spinal cord participate in motor output. GO:0021518 spinal cord commissural neuron specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021518 The process in which a cell becomes capable of differentiating autonomously into a commissural neuron in an environment that is neutral with respect to the developmental pathway. GO:0021519 spinal cord association neuron specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021519 The process in which a cell becomes capable of differentiating autonomously into an association neuron in an environment that is neutral with respect to the developmental pathway. CHEBI:71399 (beta-L-Ara4N)2-(KDO)2-lipid A(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71399 CHEBI:22385 alpha-D-glucan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22385 GO:0045556 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045556 GO:0045557 obsolete TRAIL receptor biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045557 TRAIL receptor biosynthesis|TRAIL receptor anabolism|TRAIL receptor synthesis|TRAIL receptor formation OBSOLETE. The chemical reactions and pathways resulting in the formation of the TRAIL (TNF-related apoptosis inducing ligand) receptor. GO:0045554 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045554 GO:0045555 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045555 GO:0045552 dihydrokaempferol 4-reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045552 RHEA:23016|MetaCyc:DIHYDROKAEMPFEROL-4-REDUCTASE-RXN|EC:1.1.1.219 cis-3,4-leucopelargonidin:NADP+ 4-oxidoreductase activity|dihydromyricetin reductase activity|dihydroflavonol 4-reductase activity|NADPH-dihydromyricetin reductase activity|dihydroflavanol 4-reductase activity|dihydroquercetin reductase activity Catalysis of the reaction: cis-3,4-leucopelargonidin + NADP+ = (+)-dihydrokaempferol + NADPH + H+. GO:0045553 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045553 GO:0045550 geranylgeranyl reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045550 Catalysis of the formation of phytyl group from the stepwise reduction of a geranylgeranyl group. GO:0045551 cinnamyl-alcohol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045551 RHEA:10392|EC:1.1.1.195|MetaCyc:CINNAMYL-ALCOHOL-DEHYDROGENASE-RXN CAD activity|cinnamyl-alcohol:NADP+ oxidoreductase activity|cinnamyl alcohol dehydrogenase activity Catalysis of the reaction: cinnamyl alcohol + NADP+ = cinnamaldehyde + NADPH + H+. GO:0021509 roof plate formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021509 The formation of a single row of glia at the dorsal midline of the developing neural tube. This region provides inductive signals for the specification of neuronal cell types and of the specification of neural crest cells. The cells comprising the roof plate are the precursors to radial glial cells. GO:0070518 alpha4-beta1 integrin-CD53 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070518 ITGA4-ITGB1-CD53 complex A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD53, a member of the tetraspan family. GO:0070519 alpha4-beta1 integrin-CD63 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070519 ITGA4-ITGB1-CD63 complex A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD63, a member of the tetraspan family. GO:0070516 CAK-ERCC2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070516 cyclin-dependent protein kinase activating kinase holoenzyme-ERCC2 complex A protein complex formed by the association of the cyclin-dependent protein kinase activating kinase (CAK) holoenzyme complex with ERCC2. GO:0070517 DNA replication factor C core complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070517 RFC core complex A protein complex containing three of the five subunits of eukaryotic replication factor C, those corresponding to human p40, p38, and p37. GO:0045558 obsolete TRAIL receptor 1 biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045558 TRAIL receptor 1 synthesis|TRAIL receptor 1 formation|tumor necrosis factor receptor superfamily member 10A biosynthetic process|TRAIL receptor 1 biosynthesis|TRAIL receptor 1 anabolism OBSOLETE. The chemical reactions and pathways resulting in the formation of TRAIL-R1 (TNF-related apoptosis inducing ligand receptor 1), which engages a caspase-dependent apoptotic pathway. GO:0070514 SRF-myogenin-E12 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070514 A transcription factor complex that contains the serum response factor (SRF) and the basic helix-loop-helix proteins myogenin and E12, and is involved in activating transcription of muscle-specific genes. GO:0070515 alphaIIb-beta3 integrin-talin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070515 ITGA2b-ITGB3-TLN1 complex A protein complex that consists of an alphaIIb-beta3 integrin complex bound to talin. GO:0045559 obsolete TRAIL receptor 2 biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045559 TRAIL receptor 2 synthesis|TRAIL receptor 2 formation|tumor necrosis factor receptor superfamily member 10B biosynthetic process|TRAIL receptor 2 biosynthesis|TRAIL receptor 2 anabolism OBSOLETE. The chemical reactions and pathways resulting in the formation of TRAIL-R2 (TNF-related apoptosis inducing ligand receptor 2), which engages a caspase-dependent apoptotic pathway and mediates apoptosis via the intracellular adaptor molecule FADD/MORT1. GO:0070512 positive regulation of histone H4-K20 methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070512 upregulation of histone H4-K20 methylation|stimulation of histone H4-K20 methylation|up-regulation of histone H4-K20 methylation|activation of histone H4-K20 methylation|up regulation of histone H4-K20 methylation Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 20 of histone H4. GO:0021501 prechordal plate formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021501 The formation of the prechordal plate. The prechordal plate is a thickening of the endoderm at the cranial end of the primitive streak formed by the involution of Spemann's organizer cells. The prechordal plate and the notochord induce the formation of the neural plate from the overlying ectodermal cells. GO:0070513 death domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070513 Interacting selectively and non-covalently with a death domain of a protein. The death domain (DD) is a homotypic protein interaction module composed of a bundle of six alpha-helices. DD bind each other forming oligomers. Some DD-containing proteins are involved in the regulation of apoptosis and inflammation through their activation of caspases and NF-kappaB. GO:0021502 neural fold elevation formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021502 The process in which the lateral borders of the neural plate begin to migrate upwards to form the neural folds, caused by the proliferation of the underlying mesoderm. GO:0021503 neural fold bending biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021503 The morphogenesis of the neural fold elevations that results in the movement of the tips of the elevations towards each other in order to fuse. CHEBI:71392 tetracycline(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71392 GO:0070510 regulation of histone H4-K20 methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070510 Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 20 of histone H4. GO:0070511 negative regulation of histone H4-K20 methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070511 down-regulation of histone H4-K20 methylation|downregulation of histone H4-K20 methylation|down regulation of histone H4-K20 methylation|inhibition of histone H4-K20 methylation Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 20 of histone H4. GO:0021504 neural fold hinge point formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021504 neural fold furrowing The formation of the median and lateral hinge points in the neural folds. These are created by apical constriction and basal expansion of the underlying neural cells. The median hinge point extends for the entire length of the neural tube, and the lateral hinge points do not form in the spinal cord region of the neural tube. CHEBI:71393 adenosine thiamine triphosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71393 CHEBI:71394 adenosine thiamine triphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71394 GO:0021505 neural fold folding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021505 The process of folding the neuroepithelium around the medial hinge point to create the neural elevations, and around the lateral hinge points to produce convergence of the folds. GO:0021506 anterior neuropore closure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021506 The joining together of the neural folds of the rostral opening of the neural tube. The anterior neuropore appears before the process of neural tube closure is complete. GO:0021507 posterior neuropore closure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021507 The joining together of the neural folds of the caudal opening of the neural tube. The posterior neuropore appears before the process of neural tube closure is complete. CHEBI:71397 8-oxo-dADP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71397 GO:0021508 floor plate formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021508 The formation of a ventral region of glial cells in the neural tube that provides inductive signals for the specification of neuronal cell types. The floor plate is evident at the ventral midline by the neural fold stage. GO:0045560 obsolete regulation of TRAIL receptor biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045560 regulation of TRAIL receptor biosynthesis|regulation of TRAIL receptor anabolism|regulation of TRAIL receptor synthesis|regulation of TRAIL receptor formation OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the TRAIL (TNF-related apoptosis inducing ligand) receptor. CHEBI:46345 5-fluorouracil biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46345 GO:0045567 obsolete negative regulation of TRAIL receptor 2 biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045567 negative regulation of TRAIL receptor 2 biosynthesis|down-regulation of TRAIL receptor 2 biosynthetic process|inhibition of TRAIL receptor 2 biosynthetic process|negative regulation of TRAIL receptor 2 anabolism|negative regulation of TRAIL receptor 2 synthesis|negative regulation of TRAIL receptor 2 formation|down regulation of TRAIL receptor 2 biosynthetic process|downregulation of TRAIL receptor 2 biosynthetic process OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 2. CHEBI:22390 alpha-D-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22390 GO:0045568 obsolete positive regulation of TRAIL receptor 2 biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045568 activation of TRAIL receptor 2 biosynthetic process|positive regulation of TRAIL receptor 2 biosynthesis|stimulation of TRAIL receptor 2 biosynthetic process|up-regulation of TRAIL receptor 2 biosynthetic process|positive regulation of TRAIL receptor 2 anabolism|upregulation of TRAIL receptor 2 biosynthetic process|positive regulation of TRAIL receptor 2 synthesis|positive regulation of TRAIL receptor 2 formation|up regulation of TRAIL receptor 2 biosynthetic process OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 2. GO:0045565 obsolete negative regulation of TRAIL receptor 1 biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045565 negative regulation of TRAIL receptor 1 biosynthesis|down-regulation of TRAIL receptor 1 biosynthetic process|inhibition of TRAIL receptor 1 biosynthetic process|negative regulation of TRAIL receptor 1 anabolism|negative regulation of TRAIL receptor 1 synthesis|negative regulation of TRAIL receptor 1 formation|down regulation of TRAIL receptor 1 biosynthetic process|downregulation of TRAIL receptor 1 biosynthetic process OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 1. GO:0045566 obsolete positive regulation of TRAIL receptor 1 biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045566 stimulation of TRAIL receptor 1 biosynthetic process|up-regulation of TRAIL receptor 1 biosynthetic process|positive regulation of TRAIL receptor 1 anabolism|upregulation of TRAIL receptor 1 biosynthetic process|positive regulation of TRAIL receptor 1 synthesis|positive regulation of TRAIL receptor 1 formation|up regulation of TRAIL receptor 1 biosynthetic process|activation of TRAIL receptor 1 biosynthetic process|positive regulation of TRAIL receptor 1 biosynthesis OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 1. GO:0045563 obsolete negative regulation of TRAIL receptor biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045563 negative regulation of TRAIL receptor synthesis|negative regulation of TRAIL receptor formation|down regulation of TRAIL receptor biosynthetic process|downregulation of TRAIL receptor biosynthetic process|down-regulation of TRAIL receptor biosynthetic process|negative regulation of TRAIL receptor biosynthesis|inhibition of TRAIL receptor biosynthetic process|negative regulation of TRAIL receptor anabolism OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the TRAIL (TNF-related apoptosis inducing ligand) receptor. GO:0045564 obsolete positive regulation of TRAIL receptor biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045564 positive regulation of TRAIL receptor anabolism|upregulation of TRAIL receptor biosynthetic process|positive regulation of TRAIL receptor synthesis|positive regulation of TRAIL receptor formation|up regulation of TRAIL receptor biosynthetic process|positive regulation of TRAIL receptor biosynthesis|activation of TRAIL receptor biosynthetic process|stimulation of TRAIL receptor biosynthetic process|up-regulation of TRAIL receptor biosynthetic process OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the TRAIL (TNF-related apoptosis inducing ligand) receptor. GO:0045561 obsolete regulation of TRAIL receptor 1 biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045561 regulation of TRAIL receptor 1 anabolism|regulation of TRAIL receptor 1 biosynthesis|regulation of TRAIL receptor 1 synthesis|regulation of TRAIL receptor 1 formation OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 1. GO:0045562 obsolete regulation of TRAIL receptor 2 biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045562 regulation of TRAIL receptor 2 anabolism|regulation of TRAIL receptor 2 biosynthesis|regulation of TRAIL receptor 2 synthesis|regulation of TRAIL receptor 2 formation OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 2. CHEBI:46342 undecane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46342 GO:0070509 calcium ion import biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070509 calcium ion uptake|transmembrane calcium influx The directed movement of calcium ions into a cell or organelle. GO:0070507 regulation of microtubule cytoskeleton organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070507 regulation of microtubule cytoskeleton organisation|regulation of microtubule dynamics Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. GO:0070508 cholesterol import biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070508 cholesterol uptake The directed movement of cholesterol into a cell or organelle. GO:0070505 pollen coat biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070505 pollenkitt|tryphine A layer of extracellular matrix deposited onto the surface of the pollen wall upon disintegration of the tapetal layer of the anther wall in the late stages of pollen development. The composition of this material is highly heterogeneous and includes waxes, lipid droplets, small aromatic molecules, and proteins. The pollen coat is proposed to have many functions, such as holding pollen in the anther until dispersal, facilitation of pollen dispersal, protection of pollen from water loss and UV radiation, and facilitation of adhesion of pollen to the stigma. GO:0070506 high-density lipoprotein particle receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070506 high-density lipoprotein receptor activity|HDL receptor Combining with a high-density lipoprotein particle and delivering the high-density lipoprotein into the cell via endocytosis. GO:0045569 TRAIL binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0045569 Apo-2L binding Interacting selectively and non-covalently with TRAIL (TNF-related apoptosis inducing ligand), a member of the tumor necrosis factor ligand family that rapidly induces apoptosis in a variety of transformed cell lines. GO:0070503 selenium-containing prosthetic group metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070503 selenium-containing prosthetic group metabolism The chemical reactions and pathways involving a prosthetic group that contains selenium, as in the selenium-dependent molybdenum hydroxylases. The selenium atom in the prosthetic group is required for enzymatic function but is labile to a variety of treatments. GO:0070504 selenium-containing prosthetic group biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070504 selenium-containing prosthetic group synthesis|selenium-containing prosthetic group formation|selenium-containing prosthetic group biosynthesis|selenium-containing prosthetic group anabolism The chemical reactions and pathways resulting in the formation of a prosthetic group that contains selenium, as in the selenium-dependent molybdenum hydroxylases. The selenium atom in the prosthetic group is required for enzymatic function but is labile to a variety of treatments. GO:0070501 poly-gamma-glutamate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070501 poly-gamma-glutamate anabolism|poly-gamma-glutamate biosynthesis|poly-gamma-glutamate synthesis|poly-gamma-glutamate formation The chemical reactions and pathways resulting in the formation of poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds. GO:0070502 capsule poly-gamma-glutamate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070502 capsular poly-gamma-glutamate biosynthetic process|capsule poly-gamma-glutamate anabolism|capsule poly-gamma-glutamate synthesis|capsule poly-gamma-glutamate formation|capsule poly-gamma-glutamate biosynthesis The chemical reactions and pathways resulting in the formation of poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds, that forms all or part of a bacterial capsule. GO:0070500 poly-gamma-glutamate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070500 poly-gamma-glutamate metabolism The chemical reactions and pathways involving poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds. GO:0045570 regulation of imaginal disc growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045570 Any process that modulates the frequency, rate or extent of the growth of the imaginal disc. GO:0045571 negative regulation of imaginal disc growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045571 down-regulation of imaginal disc growth|downregulation of imaginal disc growth|down regulation of imaginal disc growth|inhibition of imaginal disc growth Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc growth. GO:0045578 negative regulation of B cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045578 down regulation of B cell differentiation|inhibition of B cell differentiation|negative regulation of B-cell differentiation|negative regulation of B-lymphocyte differentiation|negative regulation of B cell development|down-regulation of B cell differentiation|negative regulation of B lymphocyte differentiation|downregulation of B cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of B cell differentiation. GO:0045579 positive regulation of B cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045579 upregulation of B cell differentiation|stimulation of B cell differentiation|positive regulation of B-cell differentiation|activation of B cell differentiation|up-regulation of B cell differentiation|positive regulation of B-lymphocyte differentiation|positive regulation of B cell development|up regulation of B cell differentiation|positive regulation of B lymphocyte differentiation Any process that activates or increases the frequency, rate or extent of B cell differentiation. GO:0045576 mast cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045576 The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors. GO:0045577 regulation of B cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045577 regulation of B lymphocyte differentiation|regulation of B-cell differentiation|regulation of B-lymphocyte differentiation|regulation of B cell development Any process that modulates the frequency, rate or extent of B cell differentiation. GO:0045574 sterigmatocystin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045574 sterigmatocystin degradation|sterigmatocystin catabolism|sterigmatocystin breakdown The chemical reactions and pathways resulting in the breakdown of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds. GO:0045575 basophil activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045575 Wikipedia:Basophil_activation The change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE bound to Fc-epsilonRI receptors. GO:0045572 positive regulation of imaginal disc growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045572 stimulation of imaginal disc growth|up-regulation of imaginal disc growth|activation of imaginal disc growth|up regulation of imaginal disc growth|upregulation of imaginal disc growth Any process that activates or increases the frequency, rate or extent of imaginal disc growth. GO:0045573 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045573 GO:0070538 oleic acid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070538 Interacting selectively and non-covalently with oleic acid, the 18-carbon monounsaturated fatty acid (9Z)-octadec-9-enoic acid. GO:0070539 linoleic acid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070539 Interacting selectively and non-covalently with linoleic acid, the 18-carbon unsaturated fatty acid (9Z,12Z)-octadeca-9,12-dienoic acid. GO:0070536 protein K63-linked deubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070536 A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a protein. GO:0070537 histone H2A K63-linked deubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070537 A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a lysine residue in histone H2A or the variant H2AX. GO:0070534 protein K63-linked ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070534 protein K63-linked polyubiquitination A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a protein. K63-linked ubiquitination does not target the substrate protein for degradation, but is involved in several pathways, notably as a signal to promote error-free DNA postreplication repair. GO:0070535 histone H2A K63-linked ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070535 A histone ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a lysine residue in histone H2A or the variant H2AX. GO:0070532 BRCA1-B complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070532 A protein complex that contains the BRCA1-BARD1 heterodimer, BACH1 and TopBP1, and binds to DNA during S phase at DNA damage sites. GO:0070533 BRCA1-C complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070533 A protein complex that contains the BRCA1-BARD1 heterodimer, CtIP and Mre11/Rad50/NBS1 (M/R/N) complex, and binds to DNA at DNA damage sites. BRCA1-C binding ta damaged DNA is required for DNA damage-induced Chk1 phosphorylation and the G2/M transition checkpoint. GO:0070530 K63-linked polyubiquitin modification-dependent protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070530 Interacting selectively and non-covalently with a protein upon poly-ubiquitination formed by linkages between lysine residues at position 63 in the target protein. GO:0070531 BRCA1-A complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070531 A protein complex that contains the BRCA1-BARD1 heterodimer, RAP80/UIMC1, BRCC3/BRCC36, BRE/BRCC45, FAM175A/CCDC98/Abraxas and MERIT40/NBA1, and specifically recognizes and binds K63-linked polyubiquitin chains present on histone H2A and H2AX at DNA damage sites. GO:0045581 negative regulation of T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045581 inhibition of T cell differentiation|negative regulation of T-cell differentiation|negative regulation of T-lymphocyte differentiation|negative regulation of T cell development|down-regulation of T cell differentiation|negative regulation of T lymphocyte differentiation|downregulation of T cell differentiation|down regulation of T cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation. GO:0045582 positive regulation of T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045582 upregulation of T cell differentiation|stimulation of T cell differentiation|positive regulation of T-cell differentiation|up-regulation of T cell differentiation|activation of T cell differentiation|positive regulation of T-lymphocyte differentiation|positive regulation of T cell development|up regulation of T cell differentiation|positive regulation of T lymphocyte differentiation Any process that activates or increases the frequency, rate or extent of T cell differentiation. GO:0045580 regulation of T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045580 regulation of T lymphocyte differentiation|regulation of T-cell differentiation|regulation of T-lymphocyte differentiation|regulation of T cell development Any process that modulates the frequency, rate or extent of T cell differentiation. GO:0045589 regulation of regulatory T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045589 regulation of regulatory T lymphocyte differentiation|regulation of suppressor T lymphocyte differentiation|regulation of suppressor T-cell differentiation|regulation of regulatory T-cell differentiation|regulation of regulatory T-lymphocyte differentiation|regulation of suppressor T-lymphocyte differentiation|regulation of regulatory T cell development|regulation of suppressor T cell differentiation Any process that modulates the frequency, rate or extent of differentiation of regulatory T cells. GO:0045587 negative regulation of gamma-delta T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045587 negative regulation of gamma-delta T cell development|down-regulation of gamma-delta T cell differentiation|negative regulation of gamma-delta T lymphocyte differentiation|downregulation of gamma-delta T cell differentiation|down regulation of gamma-delta T cell differentiation|inhibition of gamma-delta T cell differentiation|negative regulation of gamma-delta T-cell differentiation|negative regulation of gamma-delta T-lymphocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell differentiation. GO:0045588 positive regulation of gamma-delta T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045588 up-regulation of gamma-delta T cell differentiation|activation of gamma-delta T cell differentiation|positive regulation of gamma-delta T-lymphocyte differentiation|positive regulation of gamma-delta T cell development|up regulation of gamma-delta T cell differentiation|positive regulation of gamma-delta T lymphocyte differentiation|upregulation of gamma-delta T cell differentiation|stimulation of gamma-delta T cell differentiation|positive regulation of gamma-delta T-cell differentiation Any process that activates or increases the frequency, rate or extent of gamma-delta T cell differentiation. GO:0045585 positive regulation of cytotoxic T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045585 up regulation of cytotoxic T cell differentiation|positive regulation of cytotoxic T lymphocyte differentiation|upregulation of cytotoxic T cell differentiation|stimulation of cytotoxic T cell differentiation|positive regulation of cytotoxic T-cell differentiation|up-regulation of cytotoxic T cell differentiation|activation of cytotoxic T cell differentiation|positive regulation of cytotoxic T-lymphocyte differentiation|positive regulation of cytotoxic T cell development Any process that activates or increases the frequency, rate or extent of cytotoxic T cell differentiation. GO:0045586 regulation of gamma-delta T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045586 regulation of gamma-delta T-cell differentiation|regulation of gamma-delta T-lymphocyte differentiation|regulation of gamma-delta T cell development|regulation of gamma-delta T lymphocyte differentiation Any process that modulates the frequency, rate or extent of gamma-delta T cell differentiation. GO:0045583 regulation of cytotoxic T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045583 regulation of cytotoxic T cell development|regulation of cytotoxic T lymphocyte differentiation|regulation of cytotoxic T-cell differentiation|regulation of cytotoxic T-lymphocyte differentiation Any process that modulates the frequency, rate or extent of cytotoxic T cell differentiation. GO:0045584 negative regulation of cytotoxic T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045584 downregulation of cytotoxic T cell differentiation|down regulation of cytotoxic T cell differentiation|inhibition of cytotoxic T cell differentiation|negative regulation of cytotoxic T-cell differentiation|negative regulation of cytotoxic T-lymphocyte differentiation|negative regulation of cytotoxic T cell development|down-regulation of cytotoxic T cell differentiation|negative regulation of cytotoxic T lymphocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of cytotoxic T cell differentiation. GO:0070529 L-tryptophan aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070529 Catalysis of the transfer of an amino group from L-tryptophan to an acceptor, usually a 2-oxo acid. GO:0070527 platelet aggregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070527 blood platelet aggregation|thrombocyte aggregation The adhesion of one platelet to one or more other platelets via adhesion molecules. GO:0070528 protein kinase C signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070528 PKC signal transduction|protein kinase C signal transduction|PKC signaling cascade|protein kinase C signalling cascade|protein kinase C signaling cascade A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound. GO:0070525 tRNA threonylcarbamoyladenosine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070525 t6A metabolism|threonylcarbamoyladenosine metabolism|t6A metabolic process The chemical reactions and pathways involving tRNA threonylcarbamoyladenosine, a modified nucleoside found in some tRNA molecules. GO:0070526 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0070526 GO:0070523 11-beta-hydroxysteroid dehydrogenase (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070523 Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD+ = an 11-oxosteroid + NADH + H+. GO:0070524 11-beta-hydroxysteroid dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070524 MetaCyc:11-BETA-HYDROXYSTEROID-DEHYDROGENASE-RXN|RHEA:11388|EC:1.1.1.146 11beta-hydroxysteroid:NADP+ 11-oxidoreductase|corticosteroid 11-beta-dehydrogenase activity|beta-hydroxysteroid dehydrogenase Catalysis of the reaction: an 11-beta-hydroxysteroid + NADP+ = an 11-oxosteroid + NADPH + H+. GO:0070521 alpha4-beta1 integrin-CD82 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070521 A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD82, a member of the tetraspan family. GO:0070522 ERCC4-ERCC1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070522 Rad1-Rad10 complex|XPF-ERCC1 complex A heterodimeric nucleotide-excision repair complex that has endonuclease activity specific for bubble structures characteristic of certain DNA lesions. The subunits are known as XPF/ERCC4 and ERCC1 in mammals, and Rad1p and Rad10p in S. cerevisiae. GO:0070520 alpha4-beta1 integrin-CD81 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070520 ITGA4-ITGB1-CD81 complex A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD81, a member of the tetraspan family. CHEBI:40 (+)-pinoresinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_40 CHEBI:61951 microtubule-destabilising agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61951 CHEBI:61952 alpha-maltopentaose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61952 CHEBI:61950 microtubule-stabilising agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61950 CHEBI:61953 alpha-maltohexaose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61953 CHEBI:61954 alpha-maltoheptaose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61954 CHEBI:85926 (14Z)-hexadecenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85926 CHEBI:85927 (14E)-hexadecenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85927 CHEBI:61958 butane-1-sulfonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61958 CHEBI:31 (+)-menthone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_31 CHEBI:61962 S-oxy-L-cysteine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61962 CHEBI:61963 3-disulfanyl-L-alanine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61963 CHEBI:61961 N(6),N(6),N(6)-trimethyl-L-lysine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61961 CHEBI:85910 9alpha-hydroxy-3-oxo-23,24-bisnorchol-4-en-22-oic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85910 CHEBI:85911 3-oxo-23,24-bisnorchola-1,4-dien-22-oic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85911 CHEBI:61966 metabotropic glutamate receptor agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61966 CHEBI:85912 9alpha-hydroxy-3-oxo-23,24-bisnorchola-1,4-dien-22-oic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85912 CHEBI:61967 3-sulfino-L-alanine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61967 CHEBI:61964 L-cysteine-S-dioxide residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61964 CHEBI:61965 trans-4-hydroxy-L-proline residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61965 CHEBI:85914 (9Z,12Z)-hexadeca-9,12,15-trienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85914 CHEBI:61968 cis-tetradec-3-enoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61968 CHEBI:61969 N(6),N(6)-dimethyl-L-lysine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61969 CHEBI:85919 O-[S-(4Z)-hexadecenoylpantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85919 CHEBI:28 (R)-linalool biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28 CHEBI:20 (+)-camphene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_20 CHEBI:61970 N-acetyl-alpha-D-galactosamine 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61970 CHEBI:61973 S-hydroxy-L-cysteine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61973 CHEBI:61974 3-sulfino-L-alanine(1-) residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61974 CHEBI:61971 O-phospho-L-threonine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61971 CHEBI:61972 O(4)-phospho-L-tyrosine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61972 CHEBI:61977 O-phosphonato-L-threonine(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61977 CHEBI:61978 O(4)-phosphonato-L-tyrosine(2-) residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61978 CHEBI:61976 N(6),N(6)-dimethyl-L-lysine(1+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61976 GO:0021592 fourth ventricle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021592 The process whose specific outcome is the progression of the fourth ventricle over time, from its formation to the mature structure. The fourth ventricle is an irregularly shaped cavity in the rhombencephalon, between the medulla oblongata, the pons, and the isthmus in front, and the cerebellum behind. It is continuous with the central canal of the cord below and with the cerebral aqueduct above, and through its lateral and median apertures it communicates with the subarachnoid space. GO:0021593 rhombomere morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021593 The process in which the anatomical structure of the rhombomere is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. CHEBI:71300 EC 2.* (transferase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71300 GO:0021594 rhombomere formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021594 The process that gives rise to the rhombomere. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. GO:0021595 rhombomere structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021595 rhombomere structural organisation The process that contributes to the act of creating the structural organization of the rhombomere structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. CHEBI:71302 MoO2-molybdopterin cofactor(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71302 CHEBI:71304 L-gamma-glutamyl-L-amino acid(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71304 GO:0021597 central nervous system structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021597 central nervous system structural organisation The process that contributes to the act of creating the structural organization of the central nervous system structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. GO:0021598 abducens nerve morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021598 CN VI development The process in which the anatomical structure of the abducens nerve is generated and organized. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye. CHEBI:71305 WO2-molybdopterin cofactor(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71305 GO:0021599 abducens nerve formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021599 CN VI formation|CN VI biosynthesis The process that gives rise to the abducens nerve. This process pertains to the initial formation of a structure from unspecified parts. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye. CHEBI:71306 MoO2-molybdopterin cofactor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71306 CHEBI:71307 WO2-molybdopterin cofactor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71307 CHEBI:71308 Mo(VI)-molybdopterin cytosine dinucleotide(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71308 GO:0021590 cerebellum maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021590 A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellum to attain its fully functional state. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills. GO:0021591 ventricular system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021591 The process whose specific outcome is the progression of the brain ventricular system over time, from its formation to the mature structure. The brain ventricular system consists of four communicating cavities within the brain that are continuous with the central canal of the spinal cord. These cavities include two lateral ventricles, the third ventricle and the fourth ventricle. Cerebrospinal fluid fills the ventricles and is produced by the choroid plexus. CHEBI:61984 (E)-2-methylgeranyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61984 CHEBI:61985 4-carboxy-2-hydroxymuconate semialdehyde hemiacetal(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61985 CHEBI:61982 (E)-2-methylgeranyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61982 CHEBI:61983 L-Ala-gamma-D-Glu-meso-Dap-D-Ala(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61983 CHEBI:61988 alpha-maltotetraose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61988 CHEBI:85934 (2R)-2-hydroxytetradecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85934 CHEBI:61986 maltotetraose tetrasaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61986 CHEBI:61987 2-methylisoborneol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61987 CHEBI:85937 (2S)-2-hydroxytetradecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85937 CHEBI:85939 cis-3-octenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85939 GO:0021581 medulla oblongata structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021581 myelencephalon structural maturation|medulla oblongata structural organisation|medulla structural maturation The process that contributes to the act of creating the structural organization of the medulla oblongata. This process pertains to the physical shaping of a rudimentary structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate. CHEBI:71310 Mo(VI)-molybdopterin guanine dinucleotide(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71310 CHEBI:71311 pyrazine-2-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71311 GO:0021582 medulla oblongata maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021582 medulla maturation|myelencephalon maturation A developmental process, independent of morphogenetic (shape) change, that is required for the medulla oblongata to attain its fully functional state. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate. GO:0021583 pons morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021583 The process in which the anatomical structure of the pons is generated and organized. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum. CHEBI:71312 bis(molybdopterin guanine dinucleotide)molybdenum(4-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71312 CHEBI:71313 4-carboxy-2-thioxobutanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71313 GO:0021584 pons formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021584 The process that gives rise to the pons. This process pertains to the initial formation of a structure from unspecified parts. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum. GO:0021585 pons structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021585 pons structural organisation The process that contributes to the act of creating the structural organization of the pons. This process pertains to the physical shaping of a rudimentary structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum. CHEBI:89 (-)-camphene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_89 GO:0021586 pons maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021586 A developmental process, independent of morphogenetic (shape) change, that is required for the pons to attain its fully functional state. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum. CHEBI:71315 N'-monoacetylchitobiose-6'-phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71315 CHEBI:71316 (2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71316 GO:0021587 cerebellum morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021587 The process in which the anatomical structure of the cerebellum is generated and organized. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills. CHEBI:71317 N'-monoacetylchitobiose-6'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71317 GO:0021588 cerebellum formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021588 The process that gives rise to the cerebellum. This process pertains to the initial formation of a structure from unspecified parts. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills. CHEBI:80 (-)-argemonine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_80 CHEBI:61991 maltotriose trisaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61991 CHEBI:61992 sulfoacetyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61992 CHEBI:85960 (3E)-nonenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85960 GO:0021580 medulla oblongata formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021580 myelencephalon biosynthesis|medulla formation|medulla biosynthesis|myelencephalon formation The process that gives rise to the medulla oblongata. This process pertains to the initial formation of a structure from unspecified parts. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate. CHEBI:61990 15,9'-di-cis-phytofluene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61990 CHEBI:85962 1,2-dioleoyl-sn-glycero-3-phospho-N-methylethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85962 CHEBI:85963 1,2-dioleoyl-sn-glycero-3-phospho-N,N-dimethylethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85963 CHEBI:61996 maltopentaose pentasaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61996 CHEBI:61993 maltotriose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61993 CHEBI:61994 sulfoacetyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61994 CHEBI:61999 glucosyl-(heptosyl)2-4-phosphonatoheptosyl-(KDO)2-lipid A(8-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61999 PR:000007204 estrogen receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000007204 ESR|nuclear receptor subfamily 3 group A member 1|ER-alpha|NR3A1|Estra|ESR1|ER|Estr|estradiol receptor A protein that is a translation product of the human ESR1 gene or a 1:1 ortholog thereof. CHEBI:61997 glucosyl-(heptosyl)2-(KDO)2-lipid A(6-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61997 CHEBI:61998 glucosyl-heptosyl-4-phosphonatoheptosyl-(KDO)2-lipid A(8-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61998 GO:0021589 cerebellum structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021589 cerebellum structural organisation The process that contributes to the act of creating the structural organization of the cerebellum. This process pertains to the physical shaping of a rudimentary structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills. GO:0021570 rhombomere 4 development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021570 The process whose specific outcome is the progression of rhombomere 4 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. CHEBI:71321 fusidate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71321 GO:0021571 rhombomere 5 development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021571 The process whose specific outcome is the progression of rhombomere 5 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. GO:0021572 rhombomere 6 development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021572 The process whose specific outcome is the progression of rhombomere 6 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. GO:0021573 rhombomere 7 development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021573 The process whose specific outcome is the progression of rhombomere 7 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. GO:0021574 rhombomere 8 development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021574 The process whose specific outcome is the progression of rhombomere 8 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. GO:0021575 hindbrain morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021575 rhombencephalon morphogenesis The process in which the anatomical structure of the hindbrain is generated and organized. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions. GO:0021576 hindbrain formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021576 The process that gives rise to the hindbrain. This process pertains to the initial formation of a structure from unspecified parts. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions. GO:0021577 hindbrain structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021577 hindbrain structural organisation The process that contributes to the act of creating the structural organization of the hindbrain. This process pertains to the physical shaping of a rudimentary structure. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions. CHEBI:141434 monoacyl-3-O-(beta-D-galactosyl)-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_141434 CHEBI:85951 N-acyl-(4R,8Z)-4-hydroxysphing-8-enine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85951 CHEBI:85953 N-acyl-(4E,8E)-sphinga-4,8-dienine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85953 CHEBI:85955 (11E,13Z)-octadecadienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85955 CHEBI:85956 (5Z,11E)-octadecadienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85956 CHEBI:85957 (6Z,11E)-octadecadienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85957 CHEBI:85958 5'-(N(7)-methyl 5'-triphosphoguanosine)-2'-O-methyladenosine(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85958 GO:0021578 hindbrain maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021578 A developmental process, independent of morphogenetic (shape) change, that is required for the hindbrain to attain its fully functional state. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions. CHEBI:85959 5'-(N(7)-methyl 5'-triphosphoguanosine)-N(6)-methyl-2'-O-methyladenosine(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85959 GO:0021579 medulla oblongata morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021579 myelencephalon morphogenesis|medulla morphogenesis The process in which the anatomical structure of the medulla oblongata is generated and organized. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate. CHEBI:71320 cyclopeptine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71320 CHEBI:71332 (3-nitro-4-oxidophenyl)acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71332 GO:0021560 abducens nerve development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021560 CN VI development|cranial nerve 6 development|cranial nerve VI development The process whose specific outcome is the progression of the abducens nerve over time, from its formation to the mature structure. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye. GO:0021561 facial nerve development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021561 CN VII development|cranial nerve 7 development|cranial nerve VII development The process whose specific outcome is the progression of the facial nerve over time, from its formation to the mature structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives off nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities. GO:0021562 vestibulocochlear nerve development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021562 CN VIII development|cranial nerve 8 development|cranial nerve VIII development|acoustic nerve development The process whose specific outcome is the progression of the vestibulocochlear nerve over time, from its formation to the mature structure. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea. CHEBI:71335 (3R)-7,2'-dihydroxy-4'-methoxyisoflavanol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71335 GO:0021563 glossopharyngeal nerve development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021563 CN IX development|cranial nerve 9 development|cranial nerve IX development Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion. CHEBI:71337 minocycline(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71337 GO:0021564 vagus nerve development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021564 CN X development|cranial nerve X development|cranial nerve 10 development The process whose specific outcome is the progression of the vagus nerve over time, from its formation to the mature structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis. GO:0021565 accessory nerve development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021565 spinal accessory nerve development|CN XI development|cranial nerve 11 development|cranial nerve XI development The process whose specific outcome is the progression of the accessory nerve over time, from its formation to the mature structure. In mice, the spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve. CHEBI:71338 autoinducer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71338 GO:0021566 hypoglossal nerve development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021566 CN XII development|cranial nerve 12 development|cranial nerve XII development The process whose specific outcome is the progression of the hypoglossal nerve over time, from its formation to the mature structure. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue. CHEBI:71339 novobiocin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71339 CHEBI:141420 ganglioside GM2 (natural compound) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_141420 CHEBI:85985 3-deoxy-alpha-D-manno-2-octulosonate-8-phosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85985 CHEBI:85986 3-deoxy-alpha-D-manno-oct-2-ulosonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85986 CHEBI:85987 CMP-3-deoxy-beta-D-manno-octulosonate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85987 GO:0021567 rhombomere 1 development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021567 The process whose specific outcome is the progression of rhombomere 1 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. GO:0021568 rhombomere 2 development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021568 The process whose specific outcome is the progression of rhombomere 2 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. GO:0021569 rhombomere 3 development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021569 The process whose specific outcome is the progression of rhombomere 3 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. CHEBI:71343 Mo(VI)-molybdopterin guanine dinucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71343 GO:0021550 medulla oblongata development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021550 myelencephalon development|medulla development The process whose specific outcome is the progression of the medulla oblongata over time, from its formation to the mature structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate. CHEBI:71345 norsolorinate anthrone(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71345 GO:0021551 central nervous system morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021551 The process in which the anatomical structure of the central nervous system is generated and organized. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. CHEBI:71346 norsolorinate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71346 GO:0021552 midbrain-hindbrain boundary structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021552 isthmus structural organization|MHB structural organization|midbrain-hindbrain boundary structural organisation The process that contributes to the act of creating the structural organization of the midbrain-hindbrain boundary structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate. GO:0021553 olfactory nerve development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021553 CN 1 development|cranial nerve 1 development|cranial nerve I development The process whose specific outcome is the progression of the olfactory nerve over time, from its formation to the mature structure. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem. GO:0021554 optic nerve development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021554 cranial nerve 2 development|CN II development|cranial nerve II development The process whose specific outcome is the progression of the optic nerve over time, from its formation to the mature structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain. GO:0021555 midbrain-hindbrain boundary morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021555 isthmus morphogenesis|MHB morphogenesis The process in which the anatomical structure of the midbrain-hindbrain boundary is generated and organized. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate. GO:0045501 regulation of sevenless signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045501 regulation of sev signaling pathway|regulation of sevenless signalling pathway Any process that modulates the frequency, rate or extent of the sevenless signaling pathway. GO:0045502 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045502 CHEBI:53 (+)-beta-phellandrene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_53 GO:0045500 sevenless signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045500 sev signaling pathway|sevenless signalling pathway|sev receptor signaling pathway A series of molecular signals initiated by the binding of an extracellular ligand to sevenless (sev; a receptor tyrosine kinase) on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. CHEBI:85970 hydroxyaurone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85970 GO:0045509 interleukin-27 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045509 IL-27R|IL-27 receptor activity Combining with interleukin-27 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0045507 interleukin-25 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045507 IL-25R|IL-25 receptor activity Combining with interleukin-25 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. CHEBI:141417 ganglioside GM2 (24:1) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_141417 GO:0045508 interleukin-26 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045508 IL-26R|IL-26 receptor activity Combining with interleukin-26 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0045505 dynein intermediate chain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045505 Interacting selectively and non-covalently with an intermediate chain of the dynein complex. GO:0045506 interleukin-24 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045506 IL-24R|IL-24 receptor activity Combining with interleukin-24 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. CHEBI:141416 ganglioside GM2 (20:0) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_141416 GO:0045503 dynein light chain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045503 Interacting selectively and non-covalently with a light chain of the dynein complex. GO:0045504 dynein heavy chain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045504 Interacting selectively and non-covalently with a heavy chain of the dynein complex. GO:0021556 central nervous system formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021556 The process that gives rise to the central nervous system. This process pertains to the initial formation of a structure from unspecified parts. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. GO:0021557 oculomotor nerve development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021557 cranial nerve 3 development|CN III development|cranial nerve III development The process whose specific outcome is the progression of the oculomotor nerve over time, from its formation to the mature structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle. GO:0021558 trochlear nerve development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021558 CN IV development|cranial nerve 4 development|cranial nerve IV development The process whose specific outcome is the progression of the trochlear nerve over time, from its formation to the mature structure. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle. GO:0021559 trigeminal nerve development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021559 CN V development|cranial nerve V development|cranial nerve 5 development The process whose specific outcome is the progression of the trigeminal nerve over time, from its formation to the mature structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae. CHEBI:36904 elemental selenium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36904 CHEBI:12937 D-galactose 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_12937 CHEBI:36902 chalcogen hydride biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36902 CHEBI:36903 selenium hydride biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36903 CHEBI:12936 D-galactose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_12936 CHEBI:12931 D-galactonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_12931 CHEBI:36915 inorganic cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36915 CHEBI:36916 cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36916 CHEBI:36914 inorganic ion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36914 CHEBI:36919 antimony molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36919 OBA:VT0002135 kidney morphology trait biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_VT0002135 morphology of kidney The morphology of a kidney. UBERON:0003395 mesentery of rectum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003395 rectum mesentery A mesentery that is part of a rectum [Automatically generated definition]. CHEBI:12952 aldehydo-D-galacturonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_12952 UBERON:0003396 mesentery of colon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003396 mesocolon|large intestinal mesentery|large bowel mesentery|mesentery of large bowel|mesentery of large intestine|colon mesentery A mesentery that is part of a colon [Automatically generated definition]. UBERON:0003393 mesentery of urinary system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003393 mesentery of renal system|excretory system mesentery|urinary system mesentery|renal system mesentery|mesentery of systema urinaria|systema urinaria mesentery|mesentery of excretory system A mesentery that is part of a urinary system [Automatically generated definition]. UBERON:0003394 mesentery of hindgut biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003394 hindgut mesentery A mesentery that is part of a hindgut [Automatically generated definition]. UBERON:0003390 mesothelium of pleural cavity biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003390 pleural cavity meso-epithelium|pleural mesothelium|pleural cavity mesothelium|pleura|mesothelium of pleura|meso-epithelium of pleural cavity A mesothelium that is part of a pleural cavity [Automatically generated definition]. UBERON:0003397 mesentery of duodenum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003397 duodenum mesentery A mesentery that is part of a duodenum [Automatically generated definition]. UBERON:0003384 skeletal muscle tissue of pharynx biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003384 pharynx skeletal muscle tissue|pharynx skeletal muscle|skeletal muscle tissue of pharynx A portion of skeletal muscle tissue that is part of a pharynx [Automatically generated definition]. UBERON:0003382 cardiac muscle of left ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003382 left ventricle cardiac muscle|left ventricular cardiac muscle tissue|cardiac muscle tissue of left ventricle A portion of cardiac muscle tissue that is part of a left ventricle [Automatically generated definition]. UBERON:0003383 cardiac muscle tissue of interventricular septum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003383 interventricular septum heart muscle|cardiac muscle tissue of interventricular septum|cardiac muscle of interventricular septum|interventricular septum cardiac muscle|interventricular septum myocardium|interventricular septum muscle A portion of cardiac muscle tissue that is part of an interventricular septum [Automatically generated definition]. UBERON:0003380 cardiac muscle of left atrium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003380 textus muscularis of myocardium of left atrium|textus muscularis of myocardium of cardiac left atrium|cardiac muscle of cardiac left atrium|left atrium myocardium|left atrium heart muscle|cardiac left atrium cardiac muscle tissue|myocardium of left atrium|cardiac muscle of heart left atrium|textus muscularis of myocardium of heart left atrium|textus muscularis of myocardium of left cardiac atrium|cardiac muscle of left atrium of heart|textus muscularis of myocardium of left atrium of heart|cardiac left atrium cardiac muscle A portion of cardiac muscle tissue that is part of a left atrium [Automatically generated definition]. CHEBI:61900 alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61900 CHEBI:61901 alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61901 UBERON:0003381 cardiac muscle of right ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003381 cardiac muscle tissue of right ventricle|right ventricular cardiac muscle tissue|right ventricle cardiac muscle A portion of cardiac muscle tissue that is part of a right ventricle [Automatically generated definition]. CHEBI:61904 isethionate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61904 CHEBI:61905 short-chain fatty acyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61905 CHEBI:61902 hydroxy fatty acyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61902 CHEBI:61903 oxo-fatty acyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61903 UBERON:0003388 mesothelium of pericardial cavity biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003388 cavity of pericardial sac mesothelium|pericardial cavity meso-epithelium|mesothelium of cavity of pericardial sac|pericardial cavity mesothelium|cavity of pericardial sac meso-epithelium|meso-epithelium of pericardial cavity|meso-epithelium of cavity of pericardial sac A mesothelium that is part of a pericardium [Automatically generated definition]. CHEBI:61908 EC 1.14.13.39 (nitric oxide synthase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61908 UBERON:0003389 mesothelium of diaphragm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003389 meso-epithelium of diaphragm|thoracic diaphragm meso-epithelium|diaphragm mesothelium|mesothelium of thoracic diaphragm|thoracic diaphragm mesothelium|diaphragm meso-epithelium|meso-epithelium of thoracic diaphragm A mesothelium that is part of a diaphragm [Automatically generated definition]. CHEBI:61909 ethanesulfonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61909 UBERON:0003386 smooth muscle of eye biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003386 ocular smooth muscle any of the striated muscles that move the eye and include: superior rectus, inferior rectus, medial rectus, lateral rectus, superior oblique, inferior oblique, retractor bulbi CHEBI:61906 alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61906 OBA:VT0002121 metabolism trait biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_VT0002121 quality of metabolic process The quality of a metabolic process. UBERON:0003387 smooth muscle of trachea biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003387 tracheal smooth muscle|trachea smooth muscle A portion of smooth muscle tissue that is part of a trachea [Automatically generated definition]. CHEBI:61907 medium-chain fatty acyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61907 CHEBI:61911 butane-1-sulfonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61911 CHEBI:61912 branched-chain fatty acyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61912 CHEBI:61910 very long-chain fatty acyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61910 CHEBI:61915 alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61915 CHEBI:61919 alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61919 UBERON:1000004 collection of hair on external ear biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_1000004 external ear hair A collection of hairs that grows on the external ear. CHEBI:61921 alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61921 CHEBI:61927 alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61927 CHEBI:61925 alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61925 CHEBI:61928 N(6)-methyl-L-lysine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61928 CHEBI:61929 N(6)-methyl-L-lysinium residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61929 CHEBI:61930 N(6)-acetyl-L-lysine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61930 CHEBI:61933 glycerophosphoglycerol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61933 CHEBI:85900 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4-phosphate) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85900 CHEBI:85901 epivancomycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85901 CHEBI:61931 glycerol 1-phosphoserine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61931 NCBITaxon:1639119 Plasmodiidae organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_1639119 CHEBI:61932 alpha-D-Glc-(1->2)-alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61932 CHEBI:61937 alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol)(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61937 CHEBI:85904 glutathione S-sulfinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85904 CHEBI:61938 gamma-carboxy-L-glutamic acid zwitterion(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61938 CHEBI:85905 cobalt(II)-factor IV biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85905 CHEBI:85906 (2R,3S)-2,7-dihydroxy-4'-methoxyisoflavanone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85906 CHEBI:61935 alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol)(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61935 CHEBI:61936 gamma-carboxy-L-glutamic acid zwitterion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61936 CHEBI:85907 9alpha-hydroxy-3-oxo-23,24-bisnorchola-1,4-dien-22-oyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85907 CHEBI:85908 2-methyl-L-tryptophan zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85908 CHEBI:85909 9alpha-hydroxy-3-oxo-23,24-bisnorchol-4-en-22-oyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85909 CHEBI:61939 gamma-carboxy-L-glutamic acid residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61939 CHEBI:141496 4-hydroxy-L-lysine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_141496 CHEBI:61940 aroyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61940 CHEBI:61941 gamma-carboxy-L-glutamic acid(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61941 CHEBI:61944 alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol)(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61944 CHEBI:61945 alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol)(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61945 CHEBI:61942 alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol)(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61942 CHEBI:61943 alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol)(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61943 CHEBI:61948 alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol)(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61948 CHEBI:61949 alpha-D-Glc-(1->2)-alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol)(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61949 CHEBI:61946 alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol)(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61946 CHEBI:61947 alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol)(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61947 GO:0045471 response to ethanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045471 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus. GO:0045472 response to ether biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045472 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ether stimulus. GO:0045470 R8 cell-mediated photoreceptor organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045470 R8-mediated photoreceptor organisation The regionalization process that coordinates the recruitment and organization of other non-R8 photoreceptors by the R8 photoreceptor. UBERON:0003328 mesenchyme of footplate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003328 foot plate mesenchyme Mesenchyme that is part of a footplate. UBERON:0003329 submucosa of anal canal biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003329 submucosa of anal canal viewed anatomically|submucosa of anatomical anal canal|anal canal viewed anatomically submucosa|anal region submucosa|anal canal submucosa|anatomical anal canal submucosa|submucosa of anal region A submucosa that is part of an anal canal [Automatically generated definition]. GO:0045479 vesicle targeting to fusome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045479 vesicle-fusome targeting The recruitment of vesicles to the fusome. The vesicles become the fusome tubule network and are necessary for the assembly of the fusome. GO:0045477 regulation of nurse cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045477 regulation of nurse cell apoptosis Any process that modulates the frequency, rate or extent of nurse cell apoptotic process. GO:0045478 fusome organization biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0045478 fusome organisation|fusome organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome, a large intracellular spectrin-rich structure found in insect germline cells and mammalian hematopoietic cells. GO:0045475 locomotor rhythm biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045475 circadian locomotor activity rhythm The rhythm of the locomotor activity of an organism during its 24 hour activity cycle. GO:0045476 nurse cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045476 nurse cell apoptosis|nurse cell programmed cell death by apoptosis|apoptosis of nurse cells|programmed cell death of nurse cells by apoptosis|invertebrate nurse cell apoptosis Any apoptotic process in a nurse cell. During late oogenesis, following the transfer of substances from the nurse cells to the oocyte, nurse cell remnants are cleared from the egg chamber by apoptotic process. CHEBI:22340 all-cis-7,10,13-hexadecatrienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22340 GO:0045473 obsolete response to ethanol (sensu Insecta) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045473 response to ethanol (sensu Insecta) OBSOLETE. A change in state or activity of an insect (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus. GO:0045474 obsolete response to ether (sensu Insecta) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045474 response to ether (sensu Insecta) OBSOLETE. A change in state or activity of an insect (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ether stimulus. UBERON:0003330 submucosa of rectum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003330 rectal submucosa|tela submucosa recti|rectum submucosa The submucous layer of the wall of the rectum. CHEBI:36982 cyclic purine nucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36982 CHEBI:36983 cyclic pyrimidine nucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36983 GO:0070439 Mad-Max-mSin3A complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070439 A transcriptional repressor complex that contains a heterodimer of the bHLH-ZIP proteins Mad and Max, plus mSin3A, a homolog of the yeast Sin3p. CHEBI:36988 5'-deoxyribonucleoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36988 GO:0070437 Grb2-Shc complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070437 Grb2-Shc complex, EGF stimulated A protein complex that contains Grb2 and the adaptor protein Shc, and is involved in linking epidermal growth factor receptor (EGFR) activation to the p21-Ras pathway. CHEBI:36986 mesaconate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36986 GO:0070438 obsolete mTOR-FKBP12-rapamycin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070438 mTOR-FKBP12-rapamycin complex|Fkbp1a-Frap1 complex OBSOLETE. A protein complex that contains the mTOR (mammalian target of rapamycin) serine/threonine kinase, the peptidyl-prolyl cis-trans isomerase FKBP12 (FKBP1A) and rapamycin (sirolimus). CHEBI:36987 3'-deoxyribonucleoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36987 GO:0070435 Shc-EGFR complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070435 Shc-Egfr complex, EGF stimulated A protein complex that contains the epidermal growth factor receptor (EGFR) and the adaptor protein Shc, and is involved in linking EGFR activation to the p21-Ras pathway. GO:0070436 Grb2-EGFR complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070436 Grb2-Egfr complex, EGF stimulated A protein complex that contains the epidermal growth factor receptor (EGFR) and Grb2, and is involved in linking EGFR activation to the p21-Ras pathway. UBERON:0003338 ganglion of peripheral nervous system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003338 peripheral nervous system ganglion A spatially aggregated collection of nerve cell bodies in the PNS, consisting of one or more subpopulations that share cell type, chemical phenotype, and connections. (CUMBO). UBERON:0003335 serosa of colon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003335 large bowel serous membrane|large bowel serosa|serous membrane of colon|serosa of large bowel|colon serous membrane|colonic serosa|colon serosa|serous membrane of large bowel|visceral peritoneum of colon A serous membrane that is part of a colon [Automatically generated definition]. GO:0070433 negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070433 negative regulation of nucleotide-binding oligomerization domain containing 2 signalling pathway|negative regulation of NOD2 signaling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway. GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070434 positive regulation of nucleotide-binding oligomerization domain containing 2 signalling pathway|positive regulation of NOD2 signaling pathway Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway. UBERON:0003336 serosa of duodenum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003336 duodenum serosa|serous membrane of duodenum|doudenal serosa|duodenum serous membrane|visceral peritoneum of duodenum|duodenal serosa A serous membrane that is part of a duodenum [Automatically generated definition]. GO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070431 NOD2 signaling pathway|nucleotide-binding oligomerization domain containing 2 signalling pathway Any series of molecular signals generated as a consequence of binding to nucleotide-binding oligomerization domain containing 2 (NOD2). CHEBI:36980 pyridine nucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36980 CHEBI:36981 flavin nucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36981 UBERON:0003334 serosa of rectum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003334 rectal serosa|serous membrane of rectum|rectum serous membrane|rectum serosa|visceral peritoneum of rectum A serous membrane that is part of a rectum [Automatically generated definition]. GO:0070432 regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070432 regulation of NOD2 signaling pathway|regulation of nucleotide-binding oligomerization domain containing 2 signalling pathway Any process that modulates the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway. UBERON:0003331 submucosa of colon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003331 large bowel submucosa|colon submucosa|submucosa of large bowel|colonic submucosa A submucosa that is part of a colon [Automatically generated definition]. GO:0070430 positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070430 positive regulation of nucleotide-binding oligomerization domain containing 1 signalling pathway|positive regulation of NOD1 signaling pathway Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway. UBERON:0003332 submucosa of duodenum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003332 doudenal submucosa|duodenum submucosa|duodenal submucosa A submucosa that is part of a duodenum [Automatically generated definition]. GO:0045482 trichodiene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045482 EC:4.2.3.6|RHEA:12052|MetaCyc:TRICHODIENE-SYNTHASE-RXN|KEGG_REACTION:R02306 trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, trichodiene-forming)|trichodiene synthetase activity|trans,trans-farnesyl-diphosphate sesquiterpenoid-lyase activity|sesquiterpene cyclase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + trichodiene. GO:0045483 aristolochene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045483 EC:4.2.3.9|RHEA:19825|MetaCyc:ARISTOLOCHENE-SYNTHASE-RXN sesquiterpene cyclase activity|2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, aristolochene-forming)|trans,trans-farnesyl diphosphate aristolochene-lyase activity|trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, aristolochene-forming) Catalysis of the reaction: trans,trans-farnesyl diphosphate = aristolochene + diphosphate. GO:0045480 galactose oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045480 MetaCyc:GALACTOSE-OXIDASE-RXN|EC:1.1.3.9|RHEA:24160 D-galactose oxidase activity|D-galactose:oxygen 6-oxidoreductase activity|beta-galactose oxidase activity Catalysis of the reaction: D-galactose + O2 = D-galacto-hexodialdose + hydrogen peroxide. GO:0045481 6-endo-hydroxycineole dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045481 KEGG_REACTION:R02994|MetaCyc:6-ENDO-HYDROXYCINEOLE-DEHYDROGENASE-RXN|EC:1.1.1.241|RHEA:11736 6-endo-hydroxycineole:NAD+ 6-oxidoreductase activity Catalysis of the reaction: 6-endo-hydroxycineole + NAD(+) = 6-oxocineole + H(+) + NADH. UBERON:0003319 mesenchyme of carpal region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003319 mesenchyme of wrist|carpal region mesenchyme|wrist mesenchyme|carpus mesenchyme Mesenchyme of the carpal region that contributes to the carpal skeleton. CHEBI:22359 alloisoleucine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22359 UBERON:0003318 mesenchyme of elbow biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003318 mesenchyme of cubital region|cubital region mesenchyme|elbow mesenchyme Mesenchyme that is part of a developing elbow [Automatically generated definition]. GO:0045488 pectin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045488 pectin metabolism The chemical reactions and pathways involving pectin, a group of galacturonic acid-containing, water-soluble colloidal carbohydrates of high molecular weight and of net negative charge. GO:0045489 pectin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045489 pectin anabolism|pectin biosynthesis|pectin synthesis|pectin formation The chemical reactions and pathways resulting in the formation of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues. GO:0045486 naringenin 3-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045486 RHEA:18621|MetaCyc:NARINGENIN-3-DIOXYGENASE-RXN|EC:1.14.11.9 (2S)-flavanone 3-hydroxylase activity|naringenin 3-hydroxylase activity|flavanone 3-dioxygenase activity|flavanone 3-beta-hydroxylase activity|flavanone 3-hydroxylase activity|naringenin,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity|flavanone,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)|flavanone synthase I activity|flavanone 3beta-hydroxylase activity Catalysis of the reaction: naringenin + 2-oxoglutarate + O2 = dihydrokaempferol + succinate + CO2. GO:0045487 gibberellin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045487 gibberellic acid catabolic process|gibberellic acid catabolism|gibberellic acid degradation|gibberellin catabolism|gibberellic acid breakdown The chemical reactions and pathways resulting in the breakdown of gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators. GO:0045484 L-lysine 6-transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045484 RHEA:21200|MetaCyc:L-LYSINE-AMINOTRANSFERASE-RXN|KEGG_REACTION:R00457|EC:2.6.1.36 L-lysine transaminase activity|lysine epsilon-transaminase activity|L-lysine-alpha-ketoglutarate aminotransferase activity|lysine 6-aminotransferase activity|L-lysine aminotransferase activity|L-lysine:2-oxoglutarate 6-aminotransferase activity|lysine epsilon-aminotransferase activity|lysine:2-ketoglutarate 6-aminotransferase activity|L-lysine-alpha-ketoglutarate 6-aminotransferase activity Catalysis of the reaction: 2-oxoglutarate + L-lysine = L-glutamate + allysine. GO:0045485 omega-6 fatty acid desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0045485 Reactome:R-HSA-2046092|Reactome:R-HSA-2046089 Catalysis of the introduction of an omega-6 double bond into the fatty acid hydrocarbon chain. CHEBI:36995 pyrimidine 2'-deoxyribonucleoside 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36995 CHEBI:36993 purine 2'-deoxyribonucleoside 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36993 CHEBI:36994 pyrimidine 2'-deoxyribonucleoside 3'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36994 CHEBI:36999 perillic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36999 GO:0070428 regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070428 regulation of NOD1 signaling pathway|regulation of nucleotide-binding oligomerization domain containing 1 signalling pathway Any process that modulates the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway. GO:0070429 negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070429 negative regulation of NOD1 signaling pathway|negative regulation of nucleotide-binding oligomerization domain containing 1 signalling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway. GO:0070426 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070426 positive regulation of NOD signaling pathway|positive regulation of nucleotide-binding oligomerization domain containing signalling pathway Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing (NOD) pathway. GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070427 nucleotide-binding oligomerization domain containing 1 signalling pathway|NOD1 signaling pathway Any series of molecular signals generated as a consequence of binding to nucleotide-binding oligomerization domain containing 1 (NOD1). UBERON:0003326 mesenchyme of mammary gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003326 mesenchyme of lobe of breast|lobe of breast mesenchyme|mesenchyme of lobe of mammary gland|mammary gland mesenchyme|mesenchyme of lactiferous gland|lactiferous gland mesenchyme|mammary mesenchyme|lobe of mammary gland mesenchyme Mesenchyme that is part of a developing mammary gland. GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070424 regulation of NOD signaling pathway|regulation of nucleotide-binding oligomerization domain containing signalling pathway Any process that modulates the frequency, rate, or extent of a nucleotide-binding oligomerization domain containing (NOD) pathway. UBERON:0003327 mesenchyme of forearm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003327 Mesenchyme that is part of a developing lower arm [Automatically generated definition]. GO:0070425 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070425 negative regulation of NOD signaling pathway|negative regulation of nucleotide-binding oligomerization domain containing signalling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing (NOD) pathway. GO:0070422 G-protein beta/gamma-Raf-1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070422 G protein complex (GNG2, GNB2L1, RAF1) A protein complex formed by the association of the serine-threonine protein kinase Raf-1 with the beta and gamma subunits of a heterotrimeric G protein. UBERON:0003324 mesenchyme of lower jaw biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003324 lower jaw mesenchyme|mesenchyme of ventral mandibular arch|ventral mandibular arch mesenchyme Mesenchyme that is part of a developing lower jaw [Automatically generated definition]. UBERON:0003325 mesenchyme of pinna biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003325 auricle of ear mesenchyme|mesenchyme of auricula (auris externa)|mesenchyme of auricle of external ear|pinna of ear mesenchyme|mesenchyme of auricula|mesenchyme of auricle|pinna mesenchyme|auricle mesenchyme|auricula mesenchyme|mesenchyme of pinna of ear|auricula (auris externa) mesenchyme|auricle of external ear mesenchyme|mesenchyme of auricle of ear Mesenchyme that is part of a developing pinna [Automatically generated definition]. GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070423 NOD signaling pathway|nucleotide-binding oligomerization domain containing signalling pathway Any series of molecular signals generated as a consequence of binding to a nucleotide-binding oligomerization domain containing (NOD) protein. UBERON:0003322 mesenchyme of shoulder biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003322 shoulder mesenchyme Mesenchyme that is part of a developing shoulder [Automatically generated definition]. CHEBI:36991 C-glycosyl pyrimidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36991 GO:0070420 Ku-DNA ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070420 A nonhomologous end joining complex that contains one or more Ku monomers and one or more DNA ligase molecules from the LigC or LigD family, and mediates nonhomologous end joining in bacteria. UBERON:0003323 mesenchyme of upper jaw biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003323 upper jaw mesenchyme|mesenchyme of palatoquadrate arch|palatoquadrate arch mesenchyme Mesenchyme that is part of a developing upper jaw [Automatically generated definition]. GO:0070421 DNA ligase III-XRCC1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070421 A protein complex that contains DNA ligase III and XRCC1, and is involved in base excision repair. UBERON:0003320 mesenchyme of hip biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003320 hip region mesenchyme|regio coxae mesenchyme|mesenchyme of regio coxae|hip mesenchyme|mesenchyme of hip region Mesenchyme that is part of a developing hip [Automatically generated definition]. UBERON:0003321 mesenchyme of knee biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003321 knee mesenchyme Mesenchyme that is part of a developing knee [Automatically generated definition]. GO:0045493 xylan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045493 xylan breakdown|xylan catabolism|xylan degradation The chemical reactions and pathways resulting in the breakdown of xylan, a polymer containing a beta-1,4-linked D-xylose backbone. GO:0070450 interleukin4-interleukin-4 receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070450 IL4-IL4R-IL2RG complex|IL4-IL4 receptor complex A protein complex that is formed by the association of a heterodimeric interleukin-4 receptor complex with an interleukin-4 molecule. GO:0045494 photoreceptor cell maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045494 Any process preventing the degeneration of the photoreceptor, a specialized cell type that is sensitive to light. GO:0045491 xylan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045491 xylan metabolism The chemical reactions and pathways involving xylan, a polymer containing a beta-1,4-linked D-xylose backbone. GO:0045492 xylan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045492 xylan biosynthesis|xylan anabolism|xylan synthesis|xylan formation The chemical reactions and pathways resulting in the formation of xylan, a polymer containing a beta-1,4-linked D-xylose backbone. UBERON:0003308 floor plate of telencephalon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003308 floor plate telencephalic region|floor plate telencephalon|telencephalon floor plate|telencephalon floorplate|floorplate of telencephalon|floorplate telencephalon A floor plate that is part of a telencephalon [Automatically generated definition]. UBERON:0003309 floor plate of diencephalon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003309 floor plate diencephalon|interbrain floorplate|floorplate of interbrain|mature diencephalon floor plate|between brain floorplate|floorplate of between brain|floor plate diencephalic region|floorplate diencephalon|floorplate of diencephalon|floor plate of interbrain|mature diencephalon floorplate|between brain floor plate|floor plate of mature diencephalon|interbrain floor plate|diencephalon floorplate|floorplate of mature diencephalon|diencephalon floor plate|floor plate of between brain A floor plate that is part of a diencephalon [Automatically generated definition]. CHEBI:22326 S-alkylsulfenic acid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_22326 GO:0045490 pectin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045490 pectin degradation|pectin breakdown|pectin catabolism The chemical reactions and pathways resulting in the breakdown of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues. UBERON:0003306 floor plate of neural tube biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003306 floorplate neural tube|floor plate neural tube|neural tube floor plate|neural tube floorplate|floorplate of neural tube A floor plate that is part of a neural tube [Automatically generated definition]. CHEBI:22323 alkyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22323 UBERON:0003307 floor plate of midbrain biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003307 midbrain floor plate|floor plate midbrain|floor plate midbrain region|floor plate mesencephalon|floorplate of midbrain|floorplate midbrain|midbrain floorplate A floor plate that is part of a midbrain [Automatically generated definition]. CHEBI:22324 alkyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22324 NCBITaxon:9526 Catarrhini organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_9526 GO:0045499 chemorepellent activity biolink:MolecularActivity go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0045499 chemorepellant activity Providing the environmental signal that initiates the directed movement of a motile cell or organism towards a lower concentration of that signal. CHEBI:36969 farnesoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36969 GO:0045497 female analia development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045497 The process whose specific outcome is the progression of the analia of the female over time, from formation to the mature structure. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is found in Drosophila melanogaster. GO:0045498 sex comb development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045498 The process whose specific outcome is the progression of the sex comb over time, from its formation to the mature structure. The sex combs are the male specific chaetae located on the prothoracic tarsal segment of the prothoracic leg. GO:0045495 pole plasm biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0045495 germ plasm|polar plasm Differentiated cytoplasm associated with a pole (animal, vegetal, anterior, or posterior) of an oocyte, egg or early embryo. GO:0045496 male analia development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045496 The process whose specific outcome is the progression of the analia of the male over time, from formation to the mature structure. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is found in Drosophila melanogaster. CHEBI:36962 organochalcogen compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36962 CHEBI:36963 organooxygen compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36963 CHEBI:36960 carbonothioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36960 CHEBI:36961 chalcocarbonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36961 GO:0070459 prolactin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070459 The regulated release of prolactin, a peptide hormone that stimulates lactation, from secretory granules in the anterior pituitary. GO:0070457 D-galactose-1-phosphate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070457 Catalysis of the reaction: D-galactose-1-phosphate + H2O = D-galactose + phosphate. UBERON:0003315 mesenchyme of ovary biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003315 mesenchyme of female reproductive system gonad|gonad of female reproductive system mesenchyme|mesenchyme of gonada of female reproductive system|female reproductive system gonada mesenchyme|mesenchyme of female reproductive system gonada|gonada of female reproductive system mesenchyme|ovary mesenchyme|mesenchyme of gonad of female reproductive system|female reproductive system gonad mesenchyme Mesenchyme that is part of a developing ovary [Automatically generated definition]. CHEBI:22329 alkyl-sn-glycerol 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22329 UBERON:0003316 mesenchyme of yolk sac biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003316 yolk sac mesenchyme The portion of the yolk sac that is derived from mesoderm and consists of mesenchyme. GO:0070458 cellular detoxification of nitrogen compound biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070458 cellular detoxification of nitrogenous compound Any cellular process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances. GO:0070455 positive regulation of heme biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070455 upregulation of heme biosynthetic process|positive regulation of heme anabolism|positive regulation of heme synthesis|positive regulation of heme formation|up regulation of heme biosynthetic process|activation of heme biosynthetic process|positive regulation of heme biosynthesis|stimulation of heme biosynthetic process|up-regulation of heme biosynthetic process|positive regulation of haem biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme. CHEBI:22327 aliphatic sulfide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22327 GO:0070456 galactose-1-phosphate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070456 Catalysis of the reaction: galactose-1-phosphate + H2O = galactose + phosphate. UBERON:0003314 eye mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003314 mesenchyme of eye Mesenchyme that is part of a developing camera-type eye. UBERON:0003311 floor plate of medulla oblongata biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003311 floorplate medulla oblongata|floorplate of bulb|floor plate medulla oblongata|medulla oblongata floor plate|floorplate of medulla oblonmgata|metepencephalon floorplate|metepencephalon floor plate|floor plate of bulb|medulla oblongata floorplate|floor plate of medulla oblonmgata|bulb floor plate|floor plate of metepencephalon|medulla oblonmgata floor plate|medulla oblonmgata floorplate|floorplate of medulla oblongata|bulb floorplate|floorplate of metepencephalon A floor plate that is part of a medulla oblongata [Automatically generated definition]. GO:0070453 regulation of heme biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070453 regulation of heme biosynthesis|regulation of heme anabolism|regulation of heme synthesis|regulation of heme formation|regulation of haem biosynthetic process|regulation of haem biosynthesis Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme. GO:0070454 negative regulation of heme biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070454 negative regulation of haem biosynthetic process|negative regulation of heme anabolism|negative regulation of heme synthesis|down regulation of heme biosynthetic process|negative regulation of heme formation|downregulation of heme biosynthetic process|negative regulation of heme biosynthesis|down-regulation of heme biosynthetic process|inhibition of heme biosynthetic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme. UBERON:0003312 mesenchyme of testis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003312 testis mesenchyme Mesenchyme that is part of a developing testis [Automatically generated definition]. GO:0070451 cell hair biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070451 Wikipedia:Membrane_nanotube imaginal disc-derived wing hair|non-sensory hair A long, thin cell projection that contains F-actin and tubulin, with microtubules centrally located and F-actin peripherally located. UBERON:0003310 floor plate of metencephalon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003310 floorplate of metencephalon|floorplate of epencephalon-2|floorplate metencephalon|epencephalon-2 floorplate|floor plate metencephalon|metencephalon floor plate|floor plate of epencephalon-2|metencephalon floorplate|epencephalon-2 floor plate A floor plate that is part of a metencephalon [Automatically generated definition]. GO:0070452 positive regulation of ergosterol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070452 up-regulation of ergosterol biosynthetic process|upregulation of ergosterol biosynthetic process|up regulation of ergosterol biosynthetic process|activation of ergosterol biosynthetic process|positive regulation of ergosterol anabolism|positive regulation of ergosterol biosynthesis|stimulation of ergosterol biosynthetic process|positive regulation of ergosterol synthesis|positive regulation of ergosterol formation Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol. CHEBI:22332 alkylamino group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22332 CHEBI:22333 alkylating agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22333 CHEBI:22331 alkylamines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22331 CHEBI:22335 alkylglycerone phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22335 CHEBI:36979 N-glycosylpyridine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36979 UBERON:1000021 skin of face biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_1000021 face skin|facial skin A zone of skin that is part of the face. CHEBI:36974 aminoglycoside phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36974 CHEBI:36971 dodecatrienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36971 CHEBI:36972 dodeca-2,6,10-trienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36972 GO:0070448 laricitrin 5'-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070448 KEGG_REACTION:R06816|MetaCyc:RXN-8452|RHEA:25633|EC:2.1.1.267 flavonoid 3',5'-O-dimethyltransferase activity|S-adenosyl-L-methionine:myricetin O-methyltransferase activity|CrCOMT2 Catalysis of the reaction: S-adenosyl-L-methionine + laricitrin = S-adenosyl-L-homocysteine + syringetin. UBERON:1000023 spleen pulp biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_1000023 Malpighian corpuscles|splenic pulp|pulp of spleen The parenchyma of the spleen, consisting of lymphocytes and macrophages. It lies between the splenic trabecula. Red pulp is the part suffused with blood and white pulp consists of areas of lymphatic tissue where there are sleeves of lymphocytes and macrophages. UBERON:1000024 parenchyma of spleen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_1000024 splenic parenchyma A parenchyma that is part of a spleen. GO:0070449 elongin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070449 transcription factor B (SIII) complex|transcription elongation factor SIII complex|elongin (SIII) complex A transcription elongation factor complex that suppresses RNA polymerase II pausing, and may act by promoting proper alignment of the 3'-end of nascent transcripts with the polymerase catalytic site. Consists of a transcriptionally active Elongin A subunit (about 100 kDa) and two smaller Elongin B (about 18 kDa) and Elongin C (about 15 kDa) subunits. CHEBI:36976 nucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36976 GO:0070446 negative regulation of oligodendrocyte progenitor proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070446 negative regulation of oligodendrocyte precursor proliferation Any process that stops or decreases the rate or extent of oligodendrocyte progenitor proliferation. UBERON:0003304 mesoderm blood island biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003304 mesenchyme blood island|mesoderm blood islands A blood island that is part of a mesoderm. GO:0070447 positive regulation of oligodendrocyte progenitor proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070447 positive regulation of oligodendrocyte precursor proliferation Any process that activates or increases the rate or extent of oligodendrocyte progenitor proliferation. UBERON:0003302 roof plate of metencephalon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003302 epencephalon-2 roof plate|metencephalon roofplate|roofplate of epencephalon-2|metencephalon roof plate|epencephalon-2 roofplate|roofplate medulla metencephalon|roofplate of metencephalon|roof plate metencephalon|roof plate of epencephalon-2 A roof plate that is part of a metencephalon [Automatically generated definition]. GO:0070444 oligodendrocyte progenitor proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070444 oligodendrocyte precursor proliferation The multiplication or reproduction of oligodendrocyte progenitor cells by cell division, resulting in the expansion of their population. Oligodendrocyte progenitors give rise to oligodendrocytes, which form the insulating myelin sheath of axons in the central nervous system. UBERON:0003303 roof plate of medulla oblongata biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003303 roofplate of medulla oblonmgata|roofplate of medulla oblongata|bulb roofplate|roofplate of metepencephalon|medulla oblonmgata roof plate|medulla oblonmgata roofplate|roof plate of metepencephalon|bulb roof plate|roof plate medulla oblongata|roof plate of bulb|medulla oblongata roofplate|roof plate of medulla oblonmgata|metepencephalon roof plate|metepencephalon roofplate|roofplate medulla oblongata|roofplate of bulb|medulla oblongata roof plate A roof plate that is part of a medulla oblongata [Automatically generated definition]. CHEBI:22339 alkyne biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22339 GO:0070445 regulation of oligodendrocyte progenitor proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070445 regulation of oligodendrocyte precursor proliferation Any process that modulates the frequency, rate or extent of oligodendrocyte progenitor proliferation. UBERON:0003300 roof plate of telencephalon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003300 telencephalon roofplate|telencephalon roof plate|roofplate medulla telencephalon|roofplate of telencephalon|roof plate telencephalon A roof plate that is part of a telencephalon [Automatically generated definition]. GO:0070442 integrin alphaIIb-beta3 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070442 ITGA2B-ITGB3 complex|alphaIIb-beta3 integrin complex An integrin complex that comprises one alphaIIb subunit and one beta3 subunit. UBERON:0003301 roof plate of diencephalon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003301 roof plate of interbrain|mature diencephalon roofplate|between brain roof plate|roof plate of between brain|roof plate diencephalon|roofplate of interbrain|between brain roofplate|mature diencephalon roof plate|roofplate of mature diencephalon|roofplate of diencephalon|interbrain roofplate|diencephalon roof plate|roof plate of mature diencephalon|diencephalon roofplate|roofplate medulla diencephalon|roofplate of between brain|roof plate diencephalic region|interbrain roof plate A roof plate that is part of a diencephalon [Automatically generated definition]. CHEBI:36970 vitamin B6 phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36970 GO:0070443 Mad-Max complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070443 A transcriptional repressor complex that consists of a heterodimer of the bHLH-ZIP proteins Mad and Max. GO:0070440 Mad-Max-mSin3B complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070440 A transcriptional repressor complex that contains a heterodimer of the bHLH-ZIP proteins Mad and Max, plus mSin3B, a homolog of the yeast Sin3p. GO:0070441 G-protein beta/gamma-Btk complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070441 G protein complex (Btk, Gng2, Gnb1)|G protein complex (BTK, GNG1, GNG2) A protein complex formed by the association of the Bruton tyrosine protein kinase Btk, which is implicated in mammalian X-linked immunodeficiencies, with the beta and gamma subunits of a heterotrimeric G protein. GO:0070471 uterine smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070471 myometrium contraction|myometrial smooth muscle contraction|myometrial contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the uterus. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The uterus is a muscular organ of the female mammal for containing and usually for nourishing the young during development prior to birth. GO:0070472 regulation of uterine smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070472 regulation of myometrial smooth muscle contraction|regulation of myometrial contraction|regulation of myometrium contraction Any process that modulates the frequency, rate or extent of uterine smooth muscle contraction. CHEBI:22300 aldonic acid phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22300 GO:0070470 plasma membrane respirasome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070470 plasma membrane respiratory chain|plasma membrane electron transport chain A respiratory chain located in the plasma membrane of a cell; made up of the protein complexes that form the electron transport system (the respiratory chain), associated with the plasma membrane. The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient. CHEBI:22301 aldonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22301 CHEBI:22302 aldonolactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22302 CHEBI:36948 oxoalkyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36948 CHEBI:36949 hydroxyalkyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36949 CHEBI:36946 thiourea biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36946 UBERON:0003373 ectoderm of footplate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003373 An ectoderm that is part of a footplate. UBERON:0003374 chorionic ectoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003374 chorionic epithelium|chorion epithelium|chorion ectoderm A extraembryonic structure that develops_from a ectoderm and is part of a chorion. CHEBI:36941 (S)-mandelonitrile biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36941 UBERON:0003371 pelvic appendage bud ectoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003371 hindlimb ectoderm|pelvic fin bud ectoderm|leg ectoderm|hindlimb bud ectoderm|lower limb bud ectoderm|hindlimb ectoderm An unilaminar epithelium that surrounds a pelvic appendage bud. UBERON:0003372 pectoral appendage bud ectoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003372 wing ectoderm|forelimb ectoderm|pectoral fin bud ectoderm|forelimb bud ectoderm|upper limb bud ectoderm|arm ectoderm An unilaminar epithelium that surrounds a pectoral appendage bud. CHEBI:36942 pterin phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36942 CHEBI:36943 aryl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36943 GO:0070479 nuclear-transcribed mRNA catabolic process, 5'-3' exonucleolytic nonsense-mediated decay biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070479 nuclear-transcribed mRNA catabolism, 5'-3' exonucleolytic nonsense-mediated decay|5'-3' NMD|nuclear-transcribed mRNA degradation, 5'-3' exonucleolytic nonsense-mediated decay|5'-3' nonsense-mediated mRNA decay|nuclear-transcribed mRNA breakdown, 5'-3' exonucleolytic nonsense-mediated decay|5'-3' nonsense-mediated decay The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 5' end is not protected by a 5'-cap; degradation proceeds in the 5' to 3' direction. CHEBI:22307 aldoxime biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_22307 GO:0070477 endospore core biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070477 An intracellular part that represents the innermost portion of an endospore; the endospore core is dehydrated, enriched in dipicolinic acid and divalent cations, and metabolically inactive. UBERON:0003379 cardiac muscle of right atrium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003379 textus muscularis of myocardium of right cardiac atrium|cardiac muscle of cardiac right atrium|right atrium myocardium|right atrium heart muscle|textus muscularis of myocardium of right atrium|cardiac muscle tissue of right atrium of heart|cardiac muscle of heart right atrium|cardiac muscle tissue of right atrium|myocardium of right atrium|textus muscularis of myocardium of right atrium of heart|cardiac muscle tissue of heart right atrium A portion of cardiac muscle tissue that is part of a right atrium [Automatically generated definition]. GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070478 nuclear-transcribed mRNA catabolism, 3'-5' exonucleolytic nonsense-mediated decay|3'-5' NMD|nuclear-transcribed mRNA degradation, 3'-5' exonucleolytic nonsense-mediated decay|3'-5' nonsense-mediated mRNA decay|nuclear-transcribed mRNA breakdown, 3'-5' exonucleolytic nonsense-mediated decay|3'-5' nonsense-mediated decay The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction. GO:0070475 rRNA base methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070475 The addition of a methyl group to an atom in the nucleoside base portion of a nucleotide residue in an rRNA molecule. GO:0070476 rRNA (guanine-N7)-methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070476 The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an rRNA molecule. GO:0070473 negative regulation of uterine smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070473 inhibition of uterine smooth muscle contraction|down regulation of uterine smooth muscle contraction|negative regulation of myometrium contraction|downregulation of uterine smooth muscle contraction|down-regulation of uterine smooth muscle contraction|negative regulation of myometrial smooth muscle contraction|negative regulation of myometrial contraction|uterine smooth muscle relaxation Any process that decreases the frequency, rate or extent of uterine smooth muscle contraction. GO:0070474 positive regulation of uterine smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070474 positive regulation of myometrial contraction|up-regulation of uterine smooth muscle contraction|upregulation of uterine smooth muscle contraction|positive regulation of myometrium contraction|up regulation of uterine smooth muscle contraction|activation of uterine smooth muscle contraction|stimulation of uterine smooth muscle contraction|positive regulation of myometrial smooth muscle contraction Any process that increases the frequency, rate or extent of uterine smooth muscle contraction. GO:0070460 thyroid-stimulating hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070460 thyroid stimulating hormone secretion|TSH secretion The regulated release of thyroid-stimulating hormone, a peptide hormone that stimulates the activity of the thyroid gland, from secretory granules in the anterior pituitary. GO:0070461 SAGA-type complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070461 SAGA family complex A histone acetyltransferase complex that acetylates nucleosomal H3 and H2B and is required for the expression of a subset of Pol II-transcribed genes. The budding yeast complex includes the acetyltransferase Gcn5p, several proteins of the Spt and Ada families, and several TBP-associate proteins (TAFs); analogous complexes in other species have analogous compositions, and usually contain homologs of the yeast proteins. CHEBI:22314 alkali metal atom biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22314 CHEBI:22315 alkaloid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22315 CHEBI:22313 alkaline earth metal atom biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22313 CHEBI:36959 carbonothioic O,S-acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36959 OBO:GOCHE_76946 substance with fungal metabolite role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_76946 CHEBI:36958 carbonothioic O,O-acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36958 CHEBI:36951 aminoacyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36951 CHEBI:12962 D-glucosamine 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_12962 CHEBI:36952 carboxyalkyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36952 CHEBI:36954 condensed ureas biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36954 GO:0070468 dentin extracellular matrix secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070468 dentine secretion|predentin secretion|dentin secretion The regulated release by odontoblasts of the extracellular matrix constituents, including collagen, that form the basis of dentin. GO:0070469 respirasome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070469 membrane electron transport chain|respiratory chain The protein complexes that form the electron transport system (the respiratory chain), associated with a cell membrane, usually the plasma membrane (in prokaryotes) or the inner mitochondrial membrane (on eukaryotes). The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient. CHEBI:22319 alkanesulfinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22319 UBERON:0003368 epithelium of hard palate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003368 hard palate epithelium|epithelial tissue of hard palate|hard palate epithelial tissue An epithelium that is part of a hard palate [Automatically generated definition]. GO:0070466 alpha2-beta1 integrin-alpha3(VI) complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070466 ITGA2-ITGB1-COL6A3 complex A protein complex that consists of an alpha2-beta1 integrin complex bound to a type VI collagen triple helix containing an alpha3(VI) chain. GO:0070467 RC-1 DNA recombination complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070467 RC-1 complex (recombination complex 1)|DNA recombination complex RC-1 A protein complex that contains DNA ligase III, DNA polymerase epsilon, a 5'-3' exonuclease, and the SMC1 and SMC2 proteins, and is involved in recombinational repair of deletions and gaps in DNA. GO:0070464 alphav-beta3 integrin-collagen alpha3(VI) complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070464 A protein complex that consists of an alphav-beta3 integrin complex bound to the alpha3 chain of type VI collagen; the integrin binds most strongly to unfolded collagen. GO:0070465 alpha1-beta1 integrin-alpha3(VI) complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070465 ITGA1-ITGB1-COL6A3 complex A protein complex that consists of an alpha1-beta1 integrin complex bound to a type VI collagen triple helix containing an alpha3(VI) chain. UBERON:0003364 epithelium of right lung biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003364 right lung epithelium|epithelial tissue of right lung|right lung epithelial tissue An epithelium that is part of a right lung [Automatically generated definition]. GO:0070462 plus-end specific microtubule depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070462 The removal of tubulin heterodimers from the plus end of a microtubule. UBERON:0003365 epithelium of left lung biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003365 left lung epithelium|epithelial tissue of left lung|left lung epithelial tissue An epithelium that is part of a left lung [Automatically generated definition]. GO:0070463 tubulin-dependent ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070463 tubulin-activated ATPase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate. This reaction requires the presence of a tubulin dimer to accelerate release of ADP and phosphate. GO:0070493 thrombin-activated receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070493 thrombin receptor signaling pathway|thrombin receptor signalling pathway The series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands. GO:0070494 regulation of thrombin-activated receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070494 regulation of thrombin receptor signaling pathway|regulation of thrombin receptor signalling pathway Any process that modulates the frequency, rate or extent of a thrombin-activated receptor signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands. GO:0070491 repressing transcription factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070491 Interacting selectively and non-covalently with a transcription repressor, any protein whose activity is required to prevent or downregulate transcription. GO:0070492 oligosaccharide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070492 Interacting selectively and non-covalently with any oligosaccharide, a molecule with between two and (about) 20 monosaccharide residues connected by glycosidic linkages. GO:0070490 protein pupylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070490 Pup-protein conjugation|pupylation The process in which a Pup protein is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of Pup and the epsilon-amino group of a lysine residue of the target protein. CHEBI:36926 but-2-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36926 UBERON:0003351 pharyngeal epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003351 pharynx epithelium|epithelium of pharynx|epithelial tissue of pharynx|pharynx epithelial tissue An epithelium that is part of a pharynx [Automatically generated definition]. UBERON:0003352 epithelium of midgut biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003352 epithelial tissue of midgut|midgut epithelium|midgut epithelial tissue An epithelium that is part of a midgut. UBERON:0003350 epithelium of mucosa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003350 lamina epithelialis mucosae|lamina epithelialis mucosa A layer of epithelial cells on the surface of the mucosa. CHEBI:36920 antimony oxoacid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36920 CHEBI:36921 antimony oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36921 UBERON:0003359 epithelium of submandibular gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003359 submaxillary gland epithelium|submandibular duct epithelium|submandibular gland epithelium|epithelial tissue of submandibular gland|submandibular gland epithelial tissue|submandibular gland duct epithelium An epithelium that is part of a submandibular gland [Automatically generated definition]. UBERON:0003357 epithelium of tongue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003357 epithelial tissue of tongue|tongue epithelial tissue|tongue epithelium|lingual epithelium An epithelium that is part of a tongue [Automatically generated definition]. GO:0070499 exosporium assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070499 exosporium formation A process that is carried out at the cellular level which results in the formation of an exosporium, the outermost layer of a bacterial endospore. UBERON:0003358 epithelium of soft palate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003358 soft palate epithelial tissue|soft palate epithelium|epithelial tissue of soft palate An epithelium that is part of a soft palate [Automatically generated definition]. GO:0070497 6-carboxy-5,6,7,8-tetrahydropterin synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070497 MetaCyc:RXN0-5507|RHEA:27966|EC:4.1.2.50 Catalysis of the reaction: 7,8-dihydroneopterin triphosphate + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + triphosphate + acetaldehyde + 2 H+. GO:0070498 interleukin-1-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070498 interleukin-1 alpha-mediated signaling pathway|interleukin-1-mediated signalling pathway|interleukin-1 beta-mediated signaling pathway|IL-1-mediated signaling pathway|IL-1 alpha-mediated signaling pathway|IL-1 beta-mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-1 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0070495 negative regulation of thrombin-activated receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070495 negative regulation of thrombin receptor signaling pathway|negative regulation of thrombin receptor signalling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of thrombin-activated receptor protein signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands. UBERON:0003353 epithelium of hindgut biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003353 epithelial tissue of hindgut|hindgut epithelial tissue|hindgut epithelium An epithelium that is part of a hindgut [Automatically generated definition]. UBERON:0003354 epithelium of rectum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003354 epithelial tissue of rectum|rectum epithelium|rectum epithelial tissue|rectal epithelium An epithelium that is part of a rectum [Automatically generated definition]. GO:0070496 positive regulation of thrombin-activated receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070496 positive regulation of thrombin receptor signaling pathway|positive regulation of thrombin receptor signalling pathway Any process that activates or increases the frequency, rate or extent of thrombin-activated receptor protein signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands. GO:0070482 response to oxygen levels biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070482 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen. GO:0070483 detection of hypoxia biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070483 detection of reduced oxygen levels The series of events in which a stimulus indicating lowered oxygen tension is received by a cell and converted into a molecular signal. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. GO:0070480 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-independent decay biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070480 exonucleolytic nuclear-transcribed mRNA degradation involved in deadenylation-independent decay|exonucleolytic nuclear-transcribed mRNA catabolism involved in deadenylation-independent decay|exonucleolytic nuclear-transcribed mRNA breakdown involved in deadenylation-independent decay The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs independent of deadenylation, but requires decapping followed by transcript decay. GO:0070481 nuclear-transcribed mRNA catabolic process, non-stop decay biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070481 nonstop mRNA decay|nuclear-transcribed mRNA catabolism, non-stop decay|non-stop decay|nuclear-transcribed mRNA degradation, non-stop decay|nuclear-transcribed mRNA breakdown, non-stop decay|non-stop mRNA decay The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that is lacking a stop codon. UBERON:0003339 ganglion of central nervous system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003339 neuraxis ganglion|ganglion of neuraxis|central nervous system ganglion A ganglion that is part of a central nervous system [Automatically generated definition]. OBO:GOCHE_76924 substance with plant metabolite role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_76924 UBERON:0003346 mucosa of rectum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003346 rectum mucosa|mucous membrane of rectum|rectum mucosa of organ|rectum mucous membrane|organ mucosa of rectum|rectum organ mucosa|rectal mucosa|rectal mucous membrane|mucosa of organ of rectum A mucosa that is part of a rectum [Automatically generated definition]. GO:0070488 neutrophil aggregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070488 neutrophil leucocyte aggregation|neutrocyte aggregation|neutrophilic leucocyte aggregation|neutrophil leukocyte aggregation|neutrophilic leukocyte aggregation The adhesion of one neutrophil to one or more other neutrophils via adhesion molecules. GO:0070489 T cell aggregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070489 T lymphocyte aggregation|T-cell aggregation|T-lymphocyte aggregation The adhesion of one T cell to one or more other T cells via adhesion molecules. GO:0070486 leukocyte aggregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070486 white blood cell aggregation|immune cell aggregation|leucocyte aggregation|white corpuscle aggregation The adhesion of one leukocyte to one or more other leukocytes via adhesion molecules. GO:0070487 monocyte aggregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070487 mononuclear phagocyte aggregation The adhesion of one monocyte to one or more other monocytes via adhesion molecules. UBERON:0003342 mucosa of anal canal biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003342 anal region mucosa|mucous membrane of anatomical anal canal|mucosa of anatomical anal canal|anal canal viewed anatomically mucosa of organ|anal canal viewed anatomically mucosa|anal region mucosa of organ|organ mucosa of anal region|mucosa of organ of anal canal|anatomical anal canal organ mucosa|mucosa of organ of anatomical anal canal|anal canal viewed anatomically mucous membrane|anal canal organ mucosa|anal region mucous membrane|mucous membrane of anal canal|organ mucosa of anal canal viewed anatomically|anal mucous membrane|anal canal mucosa of organ|anatomical anal canal mucosa of organ|organ mucosa of anatomical anal canal|anal region organ mucosa|anal canal mucous membrane|anatomical anal canal mucosa|mucous membrane of anal region|anal canal viewed anatomically organ mucosa|anatomical anal canal mucous membrane|mucosa of anal region|anal canal mucosa|mucosa of organ of anal canal viewed anatomically|organ mucosa of anal canal|mucosa of organ of anal region|mucosa of anal canal viewed anatomically|anal mucosa|mucous membrane of anal canal viewed anatomically A mucosa that is part of an anal canal [Automatically generated definition]. GO:0070484 dehydro-D-arabinono-1,4-lactone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070484 dehydro-D-arabinono-1,4-lactone metabolism The chemical reactions and pathways involving dehydro-D-arabinono-1,4-lactone, the gamma-lactone (5R)-3,4-dihydroxy-5-(hydroxymethyl)furan-2(5H)-one. UBERON:0003343 mucosa of oral region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003343 oral opening mucous membrane|oral region mucous membrane|oral part of face organ mucosa|mucous membrane of oral part of face|mucosa of oral part of face|organ mucosa of oral opening|mucosa of organ of subdivision of mouth|subdivision of mouth organ mucosa|oral opening mucosa|mucosa of organ of oral part of face|mucous membrane of oral region|oral region mucosa|mucosa of subdivision of mouth|mucous membrane of subdivision of mouth|mucosa of organ of oral region|oral part of face mucosa|subdivision of mouth mucosa of organ|mucosa of organ of oral opening|subdivision of mouth mucous membrane|organ mucosa of oral part of face|subdivision of mouth mucosa|oral part of face mucosa of organ|mucosa of oral opening|mucous membrane of oral opening|oral opening mucosa of organ|oral part of face mucous membrane|organ mucosa of oral region|oral region mucosa of organ|oral opening organ mucosa|organ mucosa of subdivision of mouth|oral region organ mucosa A mucosa that is part of a oral opening [Automatically generated definition]. GO:0070485 dehydro-D-arabinono-1,4-lactone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070485 dehydro-D-arabinono-1,4-lactone anabolism|dehydro-D-arabinono-1,4-lactone synthesis|dehydro-D-arabinono-1,4-lactone formation|dehydro-D-arabinono-1,4-lactone biosynthesis The chemical reactions and pathways resulting in the formation of dehydro-D-arabinono-1,4-lactone, the gamma-lactone (5R)-3,4-dihydroxy-5-(hydroxymethyl)furan-2(5H)-one. CHEBI:71233 3-nitrotyramine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71233 CHEBI:71234 N-acyl-15-methylhexadecaphytosphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71234 GO:0021660 rhombomere 3 formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021660 The process that gives rise to rhombomere 3. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. CHEBI:71235 4-hydroxy-3-nitrophenylacetaldehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71235 GO:0021661 rhombomere 4 morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021661 The process in which the anatomical structure of rhombomere 4 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. CHEBI:71236 feruloylacetyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71236 CHEBI:71237 thiophene-2-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71237 GO:0021662 rhombomere 4 structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021662 rhombomere 4 structural organisation The process that contributes to creating the structural organization of rhombomere 4. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. GO:0006029 proteoglycan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006029 proteoglycan metabolism|proteoglycan sulfate transfer The chemical reactions and pathways involving proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. GO:0021663 rhombomere 4 formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021663 The process that gives rise to rhombomere 4. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. GO:0021664 rhombomere 5 morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021664 The process in which the anatomical structures of rhombomere 5 are generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. GO:0006027 glycosaminoglycan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006027 glycosaminoglycan catabolism|glycosaminoglycan breakdown|glycosaminoglycan degradation The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars. CHEBI:71239 (2Z)-4-carboxylato-2-sulfanylbut-2-enoyl-CoA(5-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71239 GO:0021665 rhombomere 5 structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021665 rhombomere 5 structural organisation The process that contributes to creating the structural organization of rhombomere 5. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. GO:0006028 galactosaminoglycan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006028 galactosaminoglycan degradation|galactosaminoglycan catabolism|galactosaminoglycan breakdown The chemical reactions and pathways resulting in the breakdown of galactosaminoglycans, any of a group of polysaccharides that contain amino sugars derived from the galactose. GO:0006025 galactosaminoglycan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006025 galactosaminoglycan synthesis|galactosaminoglycan formation|galactosaminoglycan biosynthesis|galactosaminoglycan anabolism The chemical reactions and pathways resulting in the formation of galactosaminoglycans, any of a group of polysaccharides that contain amino sugars derived from the galactose. GO:0045633 positive regulation of mechanoreceptor differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045633 up regulation of mechanoreceptor differentiation|activation of mechanoreceptor differentiation|stimulation of mechanoreceptor differentiation|up-regulation of mechanoreceptor differentiation|upregulation of mechanoreceptor differentiation Any process that activates or increases the frequency, rate or extent of mechanoreceptor differentiation. GO:0045634 regulation of melanocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045634 regulation of melanophore differentiation Any process that modulates the frequency, rate or extent of melanocyte differentiation. GO:0006026 aminoglycan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006026 aminoglycan degradation|aminoglycan breakdown|aminoglycan catabolism The chemical reactions and pathways resulting in the breakdown of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages. GO:0045631 regulation of mechanoreceptor differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045631 Any process that modulates the frequency, rate or extent of mechanoreceptor differentiation. GO:0006023 aminoglycan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006023 aminoglycan anabolism|aminoglycan biosynthesis|aminoglycan synthesis|aminoglycan formation The chemical reactions and pathways resulting in the formation of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages. GO:0045632 negative regulation of mechanoreceptor differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045632 downregulation of mechanoreceptor differentiation|down-regulation of mechanoreceptor differentiation|inhibition of mechanoreceptor differentiation|down regulation of mechanoreceptor differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of mechanoreceptor differentiation. GO:0006024 glycosaminoglycan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006024 glycosaminoglycan biosynthesis|glycosaminoglycan anabolism|glycosaminoglycan synthesis|glycosaminoglycan formation The chemical reactions and pathways resulting in the formation of glycosaminoglycans, any of a group of polysaccharides that contain amino sugars. GO:0006021 inositol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006021 inositol synthesis|inositol formation|inositol biosynthesis|vitamin Bh biosynthetic process|vitamin Bh biosynthesis|myo-inositol biosynthesis|myo-inositol biosynthetic process|inositol anabolism The chemical reactions and pathways resulting in the formation of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms. CHEBI:85881 N-octanoylsphingosine 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85881 GO:0045630 positive regulation of T-helper 2 cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045630 stimulation of T-helper 2 cell differentiation|up-regulation of T-helper 2 cell differentiation|upregulation of T-helper 2 cell differentiation|up regulation of T-helper 2 cell differentiation|positive regulation of T-helper 2 cell development|activation of T-helper 2 cell differentiation Any process that activates or increases the frequency, rate or extent of T-helper 2 cell differentiation. GO:0006022 aminoglycan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006022 aminoglycan metabolism The chemical reactions and pathways involving aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages. CHEBI:85882 N-oleoylsphingosine 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85882 GO:0006020 inositol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006020 Wikipedia:Inositol myo-inositol metabolic process|inositol metabolism|vitamin Bh metabolic process|vitamin Bh metabolism|myo-inositol metabolism The chemical reactions and pathways involving inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms. CHEBI:85886 3-dehydrocarnityl CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85886 GO:0045639 positive regulation of myeloid cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045639 up-regulation of myeloid cell differentiation|activation of myeloid cell differentiation|up regulation of myeloid cell differentiation|upregulation of myeloid cell differentiation|stimulation of myeloid cell differentiation Any process that activates or increases the frequency, rate or extent of myeloid cell differentiation. CHEBI:85888 N,N,N-trimethylglycyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85888 CHEBI:85889 (Z)-hex-3-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85889 GO:0045637 regulation of myeloid cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045637 Any process that modulates the frequency, rate or extent of myeloid cell differentiation. GO:0045638 negative regulation of myeloid cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045638 down-regulation of myeloid cell differentiation|downregulation of myeloid cell differentiation|down regulation of myeloid cell differentiation|inhibition of myeloid cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation. GO:0045635 negative regulation of melanocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045635 downregulation of melanocyte differentiation|down regulation of melanocyte differentiation|inhibition of melanocyte differentiation|negative regulation of melanophore differentiation|down-regulation of melanocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of melanocyte differentiation. GO:0045636 positive regulation of melanocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045636 up regulation of melanocyte differentiation|upregulation of melanocyte differentiation|positive regulation of melanophore differentiation|stimulation of melanocyte differentiation|up-regulation of melanocyte differentiation|activation of melanocyte differentiation Any process that activates or increases the frequency, rate or extent of melanocyte differentiation. GO:0021666 rhombomere 5 formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021666 The process that gives rise to rhombomere 5. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. GO:0021667 rhombomere 6 morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021667 The process in which the anatomical structure of rhombomere 6 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. GO:0021668 rhombomere 6 structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021668 rhombomere 6 structural organisation The process that contributes to creating the structural organization of rhombomere 6. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. GO:0021669 rhombomere 6 formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021669 The process that gives rise to rhombomere 6. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. CHEBI:71230 dihydrochalcones biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71230 CHEBI:71231 dihydrochalcone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71231 CHEBI:71232 adenosine receptor antagonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71232 CHEBI:71244 malonyl-CoA methyl ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71244 GO:0021650 vestibulocochlear nerve formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021650 CN VII formation The process that gives rise to the vestibulocochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea. GO:0021651 rhombomere 1 morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021651 The process in which the anatomical structure of rhombomere 1 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. GO:0021652 rhombomere 1 formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021652 The process that gives rise to rhombomere 1. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. GO:0021653 rhombomere 1 structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021653 rhombomere 1 structural organisation The process that contributes to creating the structural organization of rhombomere 1. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. GO:0006038 cell wall chitin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006038 cell wall chitin anabolism|cell wall chitin synthesis|cell wall chitin biosynthesis|cell wall chitin formation The chemical reactions and pathways resulting in the formation of cell wall chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in the walls of cells. GO:0021654 rhombomere boundary formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021654 The process that gives rise to a rhombomere boundary. This process pertains to the initial formation of a boundary delimiting a rhombomere. Rhombomeres are transverse segments of the developing rhombencephalon that are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. GO:0006039 cell wall chitin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006039 cell wall chitin degradation|cell wall chitin breakdown|cell wall chitin catabolism The chemical reactions and pathways resulting in the breakdown of cell wall chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in the walls of cells. GO:0045644 negative regulation of eosinophil differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045644 down-regulation of eosinophil differentiation|downregulation of eosinophil differentiation|down regulation of eosinophil differentiation|inhibition of eosinophil differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of eosinophil differentiation. GO:0006036 cuticle chitin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006036 cuticle chitin catabolism|cuticle chitin degradation|cuticle chitin breakdown The chemical reactions and pathways resulting in the breakdown of cuticle chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in cuticles. GO:0045645 positive regulation of eosinophil differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045645 up regulation of eosinophil differentiation|upregulation of eosinophil differentiation|stimulation of eosinophil differentiation|up-regulation of eosinophil differentiation|activation of eosinophil differentiation Any process that activates or increases the frequency, rate or extent of eosinophil differentiation. GO:0006037 cell wall chitin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006037 cell wall chitin metabolism The chemical reactions and pathways involving cell wall chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in the walls of cells. GO:0045642 positive regulation of basophil differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045642 up-regulation of basophil differentiation|activation of basophil differentiation|up regulation of basophil differentiation|upregulation of basophil differentiation|stimulation of basophil differentiation Any process that activates or increases the frequency, rate or extent of basophil differentiation. GO:0006034 cuticle chitin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006034 cuticle chitin metabolism The chemical reactions and pathways involving cuticle chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in cuticles. GO:0006035 cuticle chitin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006035 cuticle chitin anabolism|cuticle chitin synthesis|cuticle chitin formation|cuticle chitin biosynthesis The chemical reactions and pathways resulting in the formation of cuticle chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in cuticles. GO:0045643 regulation of eosinophil differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045643 Any process that modulates the frequency, rate or extent of eosinophil differentiation. CHEBI:46261 N-phenylthiourea biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46261 GO:0006032 chitin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006032 chitin breakdown|beta-1,4-linked N-acetylglucosamine catabolism|beta-1,4-linked N-acetylglucosamine catabolic process|chitin degradation|chitin catabolism The chemical reactions and pathways resulting in the breakdown of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues. GO:0045640 regulation of basophil differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045640 Any process that modulates the frequency, rate or extent of basophil differentiation. GO:0045641 negative regulation of basophil differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045641 down-regulation of basophil differentiation|downregulation of basophil differentiation|down regulation of basophil differentiation|inhibition of basophil differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of basophil differentiation. GO:0006033 chitin localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006033 chitin localisation|establishment and maintenance of chitin localization A process in which chitin is transported to, or maintained in, a specific location. GO:0006030 chitin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006030 chitin metabolism|beta-1,4-linked N-acetylglucosamine metabolic process|beta-1,4-linked N-acetylglucosamine metabolism The chemical reactions and pathways involving chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues. GO:0006031 chitin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006031 chitin anabolism|chitin synthesis|beta-1,4-linked N-acetylglucosamine biosynthetic process|beta-1,4-linked N-acetylglucosamine biosynthesis|chitin formation|chitin biosynthesis The chemical reactions and pathways resulting in the formation of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues. GO:0006040 amino sugar metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006040 aminosaccharide metabolic process|amino sugar metabolism|aminosaccharide metabolism The chemical reactions and pathways involving any amino sugar, sugars containing an amino group in place of a hydroxyl group. CHEBI:85876 triacylglycerol 54:6 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85876 GO:0045648 positive regulation of erythrocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045648 upregulation of erythrocyte differentiation|up regulation of erythrocyte differentiation|activation of erythrocyte differentiation|positive regulation of RBC differentiation|stimulation of erythrocyte differentiation|positive regulation of red blood cell differentiation|up-regulation of erythrocyte differentiation Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation. GO:0045649 regulation of macrophage differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045649 Any process that modulates the frequency, rate or extent of macrophage differentiation. GO:0045646 regulation of erythrocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045646 regulation of red blood cell differentiation|regulation of RBC differentiation Any process that modulates the frequency, rate or extent of erythrocyte differentiation. GO:0045647 negative regulation of erythrocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045647 down regulation of erythrocyte differentiation|downregulation of erythrocyte differentiation|negative regulation of red blood cell differentiation|negative regulation of RBC differentiation|down-regulation of erythrocyte differentiation|inhibition of erythrocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation. GO:0021655 rhombomere 2 morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021655 The process in which the anatomical structure of rhombomere 2 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. GO:0021656 rhombomere 2 structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021656 rhombomere 2 structural organisation The process that contributes to creating the structural organization of rhombomere 2. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. GO:0021657 rhombomere 2 formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021657 The process that gives rise to rhombomere 2. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. GO:0021658 rhombomere 3 morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021658 The process in which the anatomical structure of rhombomere 3 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. GO:0021659 rhombomere 3 structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021659 rhombomere 3 structural organisation The process that contributes to creating the structural organization of rhombomere 3. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. CHEBI:71241 thiophene-2-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71241 CHEBI:71242 malonyl-CoA methyl ester(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71242 CHEBI:71243 (2Z)-4-carboxy-2-sulfanylbut-2-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71243 CHEBI:22289 aldaric acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22289 GO:0006009 glucose 1-phosphate phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006009 The process of introducing a phosphate group into glucose 1-phosphate to produce glucose bisphosphate. CHEBI:71259 selenodiglutathione(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71259 GO:0006007 glucose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006007 glucose catabolism|glucose degradation|glucose breakdown The chemical reactions and pathways resulting in the breakdown of glucose, the aldohexose gluco-hexose. GO:0021640 trochlear nerve maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021640 CN IV maturation A developmental process, independent of morphogenetic (shape) change, that is required for the trochlear nerve to attain its fully functional state. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle. GO:0021641 trochlear nerve structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021641 trochlear nerve structural organisation|CN IV structural organization The process that contributes to the act of creating the structural organization of the trochlear nerve. This process pertains to the physical shaping of a rudimentary structure. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle. GO:0006008 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006008 GO:0021642 trochlear nerve formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021642 CN IV biosynthesis|CN IV formation The process that gives rise to the trochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle. GO:0006005 L-fucose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006005 L-fucose anabolism|L-fucose synthesis|L-fucose formation|L-fucose biosynthesis The chemical reactions and pathways resulting in the formation of L-fucose (6-deoxy-L-galactose). GO:0006006 glucose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006006 cellular glucose metabolic process|glucose metabolism The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides. GO:0021643 vagus nerve maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021643 CN X maturation A developmental process, independent of morphogenetic (shape) change, that is required for the vagus nerve to attain its fully functional state. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis. GO:0045655 regulation of monocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045655 Any process that modulates the frequency, rate or extent of monocyte differentiation. GO:0006003 fructose 2,6-bisphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006003 fructose 2,6-bisphosphate metabolism The chemical reactions and pathways involving fructose 2,6-bisphosphate. The D enantiomer is an important regulator of the glycolytic and gluconeogenic pathways. It inhibits fructose 1,6-bisphosphatase and activates phosphofructokinase. CHEBI:22280 alanyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22280 GO:0045656 negative regulation of monocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045656 down-regulation of monocyte differentiation|downregulation of monocyte differentiation|down regulation of monocyte differentiation|inhibition of monocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of monocyte differentiation. GO:0006004 fucose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006004 fucose metabolism The chemical reactions and pathways involving fucose, or 6-deoxygalactose, which has two enantiomers, D-fucose and L-fucose. GO:0045653 negative regulation of megakaryocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045653 down-regulation of megakaryocyte differentiation|inhibition of megakaryocyte differentiation|down regulation of megakaryocyte differentiation|downregulation of megakaryocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of megakaryocyte differentiation. GO:0006001 fructose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006001 fructose catabolism|fructose breakdown|fructose degradation The chemical reactions and pathways resulting in the breakdown of fructose, the ketohexose arabino-2-hexulose. GO:0045654 positive regulation of megakaryocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045654 stimulation of megakaryocyte differentiation|up-regulation of megakaryocyte differentiation|upregulation of megakaryocyte differentiation|up regulation of megakaryocyte differentiation|activation of megakaryocyte differentiation Any process that activates or increases the frequency, rate or extent of megakaryocyte differentiation. GO:0006002 fructose 6-phosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006002 fructose 6-phosphate metabolism The chemical reactions and pathways involving fructose 6-phosphate, also known as F6P. The D-enantiomer is an important intermediate in glycolysis, gluconeogenesis, and fructose metabolism. GO:0045651 positive regulation of macrophage differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045651 upregulation of macrophage differentiation|stimulation of macrophage differentiation|up-regulation of macrophage differentiation|activation of macrophage differentiation|up regulation of macrophage differentiation Any process that activates or increases the frequency, rate or extent of macrophage differentiation. GO:0006000 fructose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006000 Wikipedia:Fructose fructose metabolism The chemical reactions and pathways involving fructose, the ketohexose arabino-2-hexulose. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey. CHEBI:46252 5,6-diaminouracil biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46252 GO:0045652 regulation of megakaryocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045652 Any process that modulates the frequency, rate or extent of megakaryocyte differentiation. GO:0045650 negative regulation of macrophage differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045650 down-regulation of macrophage differentiation|downregulation of macrophage differentiation|down regulation of macrophage differentiation|inhibition of macrophage differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage differentiation. GO:0070619 Shc-Grb2-Sos complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070619 Shc-Grb2-mSos1 complex, EGF stimulated A protein complex that contains Grb2, the adaptor protein Shc and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway. GO:0070617 negative regulation of thiamine diphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070617 downregulation of thiamine diphosphate biosynthetic process|negative regulation of thiamine diphosphate biosynthesis|down-regulation of thiamine diphosphate biosynthetic process|inhibition of thiamine diphosphate biosynthetic process|negative regulation of thiamin diphosphate biosynthetic process|negative regulation of thiamine diphosphate anabolism|negative regulation of thiamine diphosphate synthesis|negative regulation of thiamine diphosphate formation|down regulation of thiamine diphosphate biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine diphosphate. GO:0070618 Grb2-Sos complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070618 Grb2-mSos1 complex A protein complex that contains Grb2 and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway. GO:0045659 negative regulation of neutrophil differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045659 down-regulation of neutrophil differentiation|downregulation of neutrophil differentiation|down regulation of neutrophil differentiation|inhibition of neutrophil differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of neutrophil differentiation. GO:0070615 nucleosome-dependent ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070615 nucleosome-activated ATPase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate. This reaction requires the presence of one or more nucleosomes. GO:0070616 regulation of thiamine diphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070616 regulation of thiamine diphosphate synthesis|regulation of thiamine diphosphate formation|regulation of thiamin diphosphate biosynthetic process|regulation of thiamine diphosphate anabolism|regulation of thiamine diphosphate biosynthesis Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine diphosphate. GO:0045657 positive regulation of monocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045657 up regulation of monocyte differentiation|upregulation of monocyte differentiation|stimulation of monocyte differentiation|up-regulation of monocyte differentiation|activation of monocyte differentiation Any process that activates or increases the frequency, rate or extent of monocyte differentiation. GO:0070613 regulation of protein processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070613 regulation of protein maturation by peptide bond cleavage Any process that modulates the frequency, rate or extent of protein processing, any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. GO:0045658 regulation of neutrophil differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045658 Any process that modulates the frequency, rate or extent of neutrophil differentiation. GO:0070614 tungstate ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070614 The directed movement of tungstate (WO4 2-) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Tungstate is a bivalent oxoanion of tungsten. GO:0070611 histone methyltransferase activity (H3-R2 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070611 histone methylase activity (H3-R2 specific)|histone-arginine N-methyltransferase activity (H3-R2 specific) Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 2) = S-adenosyl-L-homocysteine + (histone H3)-N-methyl-arginine (position 2). This reaction is the addition of a methyl group to arginine at position 2 of histone H3. GO:0021644 vagus nerve morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021644 CN X morphogenesis The process in which the anatomical structure of the vagus nerve is generated and organized. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis. GO:0070612 histone methyltransferase activity (H2A-R3 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070612 histone methylase activity (H2A-R3 specific)|histone-arginine N-methyltransferase activity (H2A-R3 specific) Catalysis of the reaction: S-adenosyl-L-methionine + (histone H2A)-arginine (position 3) = S-adenosyl-L-homocysteine + (histone H2A)-N-methyl-arginine (position 3). This reaction is the addition of a methyl group to arginine at position 3 of histone H2A. GO:0021645 vagus nerve structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021645 vagus nerve structural organisation|CN X structural organization The process that contributes to the act of creating the structural organization of the vagus nerve. This process pertains to the physical shaping of a rudimentary structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis. GO:0021646 vagus nerve formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021646 CN X biosynthesis|CN X formation The process that gives rise to the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis. GO:0021647 vestibulocochlear nerve maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021647 auditory nerve maturation|CN VIII maturation A developmental process, independent of morphogenetic (shape) change, that is required for the vestibulocochlear nerve to attain its fully functional state. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea. GO:0070610 regulation of fungal-type cell wall (1->3)-alpha-glucan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070610 regulation of fungal-type cell wall 1,3-alpha-glucan anabolism|regulation of fungal-type cell wall alpha-1,3-glucan anabolism|regulation of fungal type cell wall 1,3-alpha-glucan biosynthetic process|regulation of fungal-type cell wall 1,3-alpha-glucan biosynthesis|regulation of fungal-type cell wall alpha-1,3-glucan biosynthetic process|regulation of fungal-type cell wall alpha-1,3-glucan biosynthesis|regulation of fungal-type cell wall 1,3-alpha-glucan synthesis|regulation of fungal-type cell wall alpha-1,3-glucan synthesis|regulation of fungal-type cell wall 1,3-alpha-glucan formation|regulation of fungal-type cell wall alpha-1,3-glucan formation Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores. GO:0021648 vestibulocochlear nerve morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021648 CN VIII morphogenesis The process in which the anatomical structure of the vestibulocochlear nerve is generated and organized. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea. GO:0021649 vestibulocochlear nerve structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021649 CN VII structural organization|vestibulocochlear nerve structural organisation The process that contributes to the act of creating the structural organization of the vestibulocochlear nerve. This process pertains to the physical shaping of a rudimentary structure. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea. CHEBI:71266 pyrazine-2-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71266 CHEBI:22299 aldonate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22299 CHEBI:46245 coenzyme Q10 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_46245 CHEBI:22297 alditol phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22297 GO:0006018 2-deoxyribose 1-phosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006018 2-deoxyribose 1-phosphate degradation|2-deoxyribose 1-phosphate breakdown|2-deoxyribose 1-phosphate catabolism|deoxyribose 1-phosphate catabolic process The chemical reactions and pathways resulting in the breakdown of deoxyribose 1-phosphate, the phosphorylated sugar 1-phospho-2-deoxyribose. GO:0021630 olfactory nerve maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021630 CN I maturation A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory nerve to attain its fully functional state. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem. GO:0006019 deoxyribose 5-phosphate phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006019 The process of introducing a phosphate group into deoxyribose 5-phosphate to produce deoxyribose bisphosphate. GO:0021631 optic nerve morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021631 CN II morphogenesis The process in which the anatomical structure of the optic nerve is generated and organized. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain. GO:0006016 2-deoxyribose 1-phosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006016 2-deoxyribose 1-phosphate anabolism|2-deoxyribose 1-phosphate biosynthesis|2-deoxyribose 1-phosphate synthesis|2-deoxyribose 1-phosphate formation The chemical reactions and pathways resulting in the formation of 2-deoxyribose 1-phosphate, the phosphorylated sugar 1-phospho-2-deoxyribose. GO:0006017 deoxyribose 1,5-bisphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006017 deoxyribose 1,5-bisphosphate anabolism|deoxyribose 1,5-bisphosphate synthesis|deoxyribose 1,5-bisphosphate formation|deoxyribose 1,5-bisphosphate biosynthesis The chemical reactions and pathways resulting in the formation of deoxyribose 1,5-bisphosphate, the diphosphorylated sugar 1,5-diphospho-2-deoxyribose. GO:0021632 optic nerve maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021632 CN II maturation A developmental process, independent of morphogenetic (shape) change, that is required for the optic nerve to attain its fully functional state. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain. GO:0045666 positive regulation of neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045666 up-regulation of neuron differentiation|activation of neuron differentiation|up regulation of neuron differentiation|upregulation of neuron differentiation|stimulation of neuron differentiation Any process that activates or increases the frequency, rate or extent of neuron differentiation. GO:0006014 D-ribose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006014 D-ribose metabolism The chemical reactions and pathways involving D-ribose (ribo-pentose). As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12. GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006015 MetaCyc:PWY0-661 5-phosphoribose 1-diphosphate biosynthesis|5-phosphoribose 1-diphosphate anabolism|5-phosphoribose 1-diphosphate synthesis|PRPP biosynthetic process|5-phosphoribose 1-diphosphate formation|5-phosphoribosyl-1-pyrophosphate biosynthetic process|5-phosphoribosyl-1-pyrophosphate biosynthesis The chemical reactions and pathways resulting in the formation of 5-phosphoribose 1-diphosphate, also known as 5-phosphoribosyl-1-pyrophosphate. GO:0045667 regulation of osteoblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045667 Any process that modulates the frequency, rate or extent of osteoblast differentiation. CHEBI:22292 alditol 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22292 GO:0006012 galactose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006012 Wikipedia:Galactose galactose metabolism The chemical reactions and pathways involving galactose, the aldohexose galacto-hexose. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose. GO:0045664 regulation of neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045664 Any process that modulates the frequency, rate or extent of neuron differentiation. GO:0045665 negative regulation of neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045665 down-regulation of neuron differentiation|downregulation of neuron differentiation|down regulation of neuron differentiation|inhibition of neuron differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation. GO:0006013 mannose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006013 mannose metabolism The chemical reactions and pathways involving mannose, the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins. CHEBI:85891 N-isopropyl-L-glutamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85891 CHEBI:22290 aldaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22290 GO:0006010 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006010 GO:0045662 negative regulation of myoblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045662 down-regulation of myoblast differentiation|downregulation of myoblast differentiation|down regulation of myoblast differentiation|inhibition of myoblast differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. CHEBI:22295 alditol 5-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22295 GO:0006011 UDP-glucose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006011 UDP-glucose metabolism The chemical reactions and pathways involving UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate. GO:0045663 positive regulation of myoblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045663 up regulation of myoblast differentiation|upregulation of myoblast differentiation|stimulation of myoblast differentiation|activation of myoblast differentiation|up-regulation of myoblast differentiation Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. GO:0045660 positive regulation of neutrophil differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045660 stimulation of neutrophil differentiation|up-regulation of neutrophil differentiation|activation of neutrophil differentiation|up regulation of neutrophil differentiation|upregulation of neutrophil differentiation Any process that activates or increases the frequency, rate or extent of neutrophil differentiation. CHEBI:85894 N-(gamma-L-glutamyl)-L-alaninol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85894 GO:0045661 regulation of myoblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045661 Any process that modulates the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. CHEBI:22294 alditol 4-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22294 CHEBI:85895 4-amino-5-formamidomethyl-2-methylpyrimidine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85895 GO:0070608 regulation of cell wall (1->3)-alpha-glucan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070608 regulation of cell wall 1,3-alpha-glucan anabolism|regulation of cell wall alpha-1,3-glucan anabolism|regulation of cell wall 1,3-alpha-glucan synthesis|regulation of cell wall alpha-1,3-glucan synthesis|regulation of cell wall 1,3-alpha-glucan formation|regulation of cell wall alpha-1,3-glucan formation|regulation of cell wall alpha-1,3-glucan biosynthesis|regulation of cell wall alpha-1,3-glucan biosynthetic process|regulation of cell wall 1,3-alpha-glucan biosynthetic process|regulation of cell wall 1,3-alpha-glucan biosynthesis Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells. CHEBI:85897 11-deoxy-beta-rhodomycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85897 GO:0070609 regulation of fungal-type cell wall (1->3)-alpha-glucan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070609 regulation of ascospore wall alpha-1,3 glucan metabolism|regulation of ascospore wall alpha-1,3 glucan metabolic process|regulation of fungal-type cell wall 1,3-alpha-glucan metabolic process|regulation of ascospore wall 1,3-alpha-glucan metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of ascospores. GO:0070606 regulation of (1->3)-alpha-glucan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070606 regulation of 1,3-alpha-glucan anabolism|regulation of 1,3-alpha-glucan synthesis|regulation of 1,3-alpha-glucan formation|regulation of alpha-1,3 glucan biosynthesis|regulation of alpha-1,3 glucan anabolism|regulation of alpha-1,3 glucan biosynthetic process|regulation of alpha-1,3 glucan synthesis|regulation of alpha-1,3 glucan formation|regulation of 1,3-alpha-glucan biosynthetic process|regulation of 1,3-alpha-glucan biosynthesis Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds. CHEBI:85899 4-pregnen-3beta-ol-20-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85899 GO:0070607 regulation of cell wall (1->3)-alpha-glucan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070607 regulation of cell wall alpha-1,3 glucan metabolism|regulation of cell wall alpha-1,3 glucan metabolic process|regulation of cell wall 1,3-alpha-glucan metabolism|regulation of cell wall 1,3-alpha-glucan metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells. GO:0070604 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0070604 GO:0070605 regulation of (1->3)-alpha-glucan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070605 regulation of alpha-1,3 glucan metabolic process|regulation of alpha-1,3 glucan metabolism|regulation of 1,3-alpha-glucan metabolic process|regulation of 1,3-alpha-glucan metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds. GO:0070602 regulation of centromeric sister chromatid cohesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070602 regulation of sister chromatid cohesion at centromere Any process that modulates the frequency, rate or extent of sister chromatid cohesion in the centromeric region of a chromosome. GO:0045668 negative regulation of osteoblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045668 downregulation of osteoblast differentiation|down regulation of osteoblast differentiation|inhibition of osteoblast differentiation|down-regulation of osteoblast differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of osteoblast differentiation. GO:0070603 SWI/SNF superfamily-type complex biolink:CellularComponent go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0070603 SWI-SNF global transcription activator complex|SWI/SNF-type complex|SWI2/SNF2 superfamily ATP-dependent chromatin remodeling complex|BAF-type complex|SWI-SNF-type complex A protein complex that contains an ortholog of the Saccharomyces ATPase Swi2/Snf2 as one of the catalytic subunit components (ATPase) and mediates assembly of nucleosomes, changes to the spacing or structure of nucleosomes, or some combination of those activities in a manner that requires ATP. GO:0045669 positive regulation of osteoblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045669 up regulation of osteoblast differentiation|upregulation of osteoblast differentiation|stimulation of osteoblast differentiation|up-regulation of osteoblast differentiation|activation of osteoblast differentiation Any process that activates or increases the frequency, rate or extent of osteoblast differentiation. GO:0021633 optic nerve structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021633 optic nerve structural organisation|CN II structural organization The process that contributes to the act of creating the structural organization of the optic nerve. This process pertains to the physical shaping of a rudimentary structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain. GO:0070600 fungal-type cell wall (1->3)-alpha-glucan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070600 fungal-type cell wall 1,3-alpha-glucan biosynthesis|fungal-type cell wall 1,3-alpha-glucan biosynthetic process|fungal-type cell wall alpha-1,3-glucan biosynthetic process|fungal-type cell wall alpha-1,3-glucan biosynthesis|fungal-type cell wall alpha-1,3-glucan anabolism|fungal-type cell wall 1,3-alpha-glucan anabolism|fungal-type cell wall alpha-1,3-glucan synthesis|fungal-type cell wall 1,3-alpha-glucan synthesis|fungal-type cell wall alpha-1,3-glucan formation|fungal-type cell wall 1,3-alpha-glucan formation The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores. GO:0070601 centromeric sister chromatid cohesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070601 sister chromatid cohesion at centromere The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the centromeric region of the chromosome. GO:0021634 optic nerve formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021634 CN II biosynthesis|CN II formation The process that gives rise to the optic nerve. This process pertains to the initial formation of a structure from unspecified parts. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain. GO:0021635 trigeminal nerve maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021635 CN V maturation A developmental process, independent of morphogenetic (shape) change, that is required for the trigeminal nerve to attain its fully functional state. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae. CHEBI:71261 S-(2-hydroxyacyl)glutathione(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71261 GO:0021636 trigeminal nerve morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021636 CN V morphogenesis The process in which the anatomical structure of the trigeminal nerve is generated and organized. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae. GO:0021637 trigeminal nerve structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021637 trigeminal nerve structural organisation|CN V structural organization The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae. GO:0021638 trigeminal nerve formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021638 CN V formation|CN V biosynthesis The process that gives rise to the trigeminal nerve. This process pertains to the initial formation of a structure from unspecified parts. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae. GO:0021639 trochlear nerve morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021639 CH IV morphogenesis The process in which the anatomical structure of the trochlear nerve is generated and organized. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle. CHEBI:71265 glutathioselenol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71265 CHEBI:22266 adipate semialdehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22266 CHEBI:71277 4-carboxylato-2-thioxobutanoyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71277 GO:0045670 regulation of osteoclast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045670 Any process that modulates the frequency, rate or extent of osteoclast differentiation. UBERON:0003409 gland of tongue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003409 lingual gland|tongue gland Any of the mucous, serous, or mixed glands that empty their secretions onto the surface of the tongue. UBERON:0003408 gland of digestive tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003408 lower gastrointestinal tract gland|digestive tract gland|gut gland|gland of lower gastrointestinal tract|gland of digestive tract A gland that is part of a digestive tract [Automatically generated definition]. UBERON:0003405 lobar bronchus of left lung biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003405 left lung secondary bronchus|left lobar bronchus|secondary bronchus of left lung|left lung lobar bronchus A lobar bronchus that is part of a left lung [Automatically generated definition]. GO:0021620 hypoglossal nerve formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021620 CN XII biosynthesis|CN XII formation The process that gives rise to the hypoglossal nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue. UBERON:0003406 cartilage of respiratory system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003406 respiratory system cartilage|apparatus respiratorius cartilage|cartilage of apparatus respiratorius A cartilage element that is part of a respiratory system [Automatically generated definition]. GO:0021621 hypoglossal nerve structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021621 CN XII structural organization|hypoglossal nerve structural organisation The process that contributes to the act of creating the structural organization of the hypoglossal nerve. This process pertains to the physical shaping of a rudimentary structure. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue. GO:0045677 negative regulation of R7 cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045677 down-regulation of R7 differentiation|downregulation of R7 differentiation|down regulation of R7 differentiation|inhibition of R7 differentiation|negative regulation of R7 differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of R7cell differentiation. GO:0045678 positive regulation of R7 cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045678 up regulation of R7 differentiation|upregulation of R7 differentiation|stimulation of R7 differentiation|up-regulation of R7 differentiation|positive regulation of R7 differentiation|activation of R7 differentiation Any process that activates or increases the frequency, rate or extent of R7 cell differentiation. GO:0045675 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045675 GO:0045676 regulation of R7 cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045676 Any process that modulates the frequency, rate or extent of R7 differentiation. GO:0045673 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045673 GO:0045674 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0045674 CHEBI:22263 5'-adenylyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22263 CHEBI:22260 adenosines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22260 GO:0045671 negative regulation of osteoclast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045671 down-regulation of osteoclast differentiation|downregulation of osteoclast differentiation|down regulation of osteoclast differentiation|inhibition of osteoclast differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of osteoclast differentiation. GO:0045672 positive regulation of osteoclast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045672 up-regulation of osteoclast differentiation|activation of osteoclast differentiation|up regulation of osteoclast differentiation|upregulation of osteoclast differentiation|stimulation of osteoclast differentiation Any process that activates or increases the frequency, rate or extent of osteoclast differentiation. GO:0070639 vitamin D2 metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070639 calciferol metabolic process|vitamin D2 metabolism|ergocalciferol metabolic process The chemical reactions and pathways involving vitamin D2, (3S,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol. GO:0070637 pyridine nucleoside metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070637 pyridine nucleoside metabolism The chemical reactions and pathways involving any pyridine nucleoside, a nucleoside in which a pyridine base covalently bonded to a sugar, usually ribose. GO:0070638 pyridine nucleoside catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070638 pyridine nucleoside degradation|pyridine nucleoside catabolism|pyridine nucleoside breakdown The chemical reactions and pathways resulting in the breakdown of any pyridine nucleoside, a nucleoside in which a pyridine base covalently bonded to a sugar, usually ribose. GO:0045679 regulation of R8 cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045679 Any process that modulates the frequency, rate or extent of R8 differentiation. GO:0070635 nicotinamide riboside hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070635 MetaCyc:RXN-8441 N-ribosylnicotinamide hydrolase activity|nicotinamide ribonucleoside hydrolase activity Catalysis of the reaction: nicotinamide riboside + H2O = nicotinamide + D-ribose. GO:0070636 nicotinic acid riboside hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070636 nicotinic acid ribonucleoside hydrolase activity|nicotinate ribonucleoside hydrolase activity|D-ribosylnicotinic acid hydrolase activity|D-ribosylnicotinate hydrolase activity|nicotinate riboside hydrolase activity Catalysis of the reaction: nicotinic acid riboside + H2O = nicotinic acid + D-ribose. GO:0070633 transepithelial transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070633 The directed movement of a substance from one side of an epithelium to the other. GO:0021622 oculomotor nerve morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021622 CN III morphogenesis The process in which the anatomical structure of the oculomotor nerve is generated and organized. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle. GO:0070634 transepithelial ammonium transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070634 The directed movement of ammonium ions from one side of an epithelium to the other. GO:0021623 oculomotor nerve formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021623 CN III formation|CN III biosynthesis The process that gives rise to the oculomotor nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle. GO:0070631 spindle pole body localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070631 maintenance of spindle pole body localization|spindle pole body localisation Any process in which a spindle pole body is transported to, or maintained in, a specific location. A spindle pole body is a type of microtubule organizing center found in fungal cells. GO:0021624 oculomotor nerve structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021624 CN III structural organization|oculomotor nerve structural organisation The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle. UBERON:0003412 pelvic appendage bud mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003412 mesoderm pelvic fin bud|lower limb bud mesenchyme|leg mesenchyme|pelvic fin bud mesenchyme|hindlimb bud mesenchyme Mesenchyme that is part of a pelvic appendage bud. GO:0070632 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0070632 UBERON:0003413 pectoral appendage bud mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003413 arm mesenchyme|forelimb bud mesenchyme|upper limb bud mesenchyme|mesoderm pectoral fin bud|wing mesenchyme|pectoral fin bud mesenchyme Mesenchyme that is part of a pectoral appendage bud. GO:0021625 oculomotor nerve maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021625 CN III maturation A developmental process, independent of morphogenetic (shape) change, that is required for the oculomotor nerve to attain its fully functional state. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle. GO:0021626 central nervous system maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021626 A developmental process, independent of morphogenetic (shape) change, that is required for the central nervous system to attain its fully functional state. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. GO:0070630 (1->4)-alpha-glucan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070630 1,4-alpha-glucan synthesis|alpha-1,4 glucan biosynthetic process|alpha-1,4 glucan biosynthesis|(1->4)-alpha-D-glucan biosynthesis|1,4-alpha-glucan formation|(1->4)-alpha-D-glucan anabolism|alpha-1,4 glucan anabolism|(1->4)-alpha-D-glucan synthesis|alpha-1,4 glucan synthesis|1,4-alpha-glucan biosynthesis|1,4-alpha-glucan biosynthetic process|(1->4)-alpha-D-glucan formation|alpha-1,4 glucan formation|1,4-alpha-glucan anabolism The chemical reactions and pathways resulting in the formation of (1->4)-alpha-glucans, compounds composed of glucose residues linked by (1->4)-alpha-D-glucosidic bonds. CHEBI:71274 mannooligosaccharide derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71274 GO:0021627 olfactory nerve morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021627 CN I morphogenesis The process in which the anatomical structure of the olfactory nerve is generated and organized. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem. GO:0021628 olfactory nerve formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021628 CN I formation|CN I biosynthesis The process that gives rise to the olfactory nerve. This process pertains to the initial formation of a structure from unspecified parts. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem. GO:0021629 olfactory nerve structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021629 CN I structural organization|olfactory nerve structural organisation The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem. GO:0045680 negative regulation of R8 cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045680 negative regulation of R8 differentiation|down-regulation of R8 differentiation|downregulation of R8 differentiation|down regulation of R8 differentiation|inhibition of R8 differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of R8 cell differentiation. CHEBI:71288 (1->3)-alpha-D-mannooligosaccharide derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71288 GO:0045681 positive regulation of R8 cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045681 stimulation of R8 differentiation|activation of R8 differentiation|up-regulation of R8 differentiation|positive regulation of R8 differentiation|up regulation of R8 differentiation|upregulation of R8 differentiation Any process that activates or increases the frequency, rate or extent of R8 cell differentiation. CHEBI:22278 alanine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22278 GO:0055007 cardiac muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055007 cardiomyocyte differentiation|heart muscle cell differentiation The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. GO:0055008 cardiac muscle tissue morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055008 myocardium morphogenesis|heart muscle morphogenesis The process in which the anatomical structures of cardiac muscle tissue are generated and organized. GO:0055009 atrial cardiac muscle tissue morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055009 cardiac atrium muscle morphogenesis|atrial myocardium morphogenesis|atrial heart muscle morphogenesis The process in which the anatomical structure of cardiac atrium muscle is generated and organized. GO:0021610 facial nerve morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021610 CN VII morphogenesis The process in which the anatomical structure of the facial nerve is generated and organized. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities. CHEBI:46229 UDP-alpha-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46229 GO:0045688 regulation of antipodal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045688 Any process that modulates the frequency, rate or extent of antipodal cell differentiation. GO:0045689 negative regulation of antipodal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045689 down-regulation of antipodal cell differentiation|downregulation of antipodal cell differentiation|down regulation of antipodal cell differentiation|inhibition of antipodal cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of antipodal cell differentiation. GO:0045686 negative regulation of glial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045686 down-regulation of glial cell differentiation|downregulation of glial cell differentiation|negative regulation of glia cell differentiation|down regulation of glial cell differentiation|inhibition of glial cell differentiation|negative regulation of neuroglia differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of glia cell differentiation. GO:0045687 positive regulation of glial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045687 up regulation of glial cell differentiation|positive regulation of glia cell differentiation|upregulation of glial cell differentiation|positive regulation of neuroglia differentiation|stimulation of glial cell differentiation|activation of glial cell differentiation|up-regulation of glial cell differentiation Any process that activates or increases the frequency, rate or extent of glia cell differentiation. GO:0045684 positive regulation of epidermis development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045684 upregulation of epidermis development|up regulation of epidermis development|positive regulation of epidermal development|activation of epidermis development|stimulation of epidermis development|positive regulation of hypodermis development|up-regulation of epidermis development Any process that activates or increases the frequency, rate or extent of epidermis development. GO:0045685 regulation of glial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045685 regulation of glia cell differentiation|regulation of neuroglia differentiation Any process that modulates the frequency, rate or extent of glia cell differentiation. GO:0045682 regulation of epidermis development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045682 regulation of hypodermis development|regulation of epidermal development Any process that modulates the frequency, rate or extent of epidermis development. CHEBI:22271 aflatoxin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22271 GO:0045683 negative regulation of epidermis development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045683 down regulation of epidermis development|downregulation of epidermis development|negative regulation of epidermal development|negative regulation of hypodermis development|down-regulation of epidermis development|inhibition of epidermis development Any process that stops, prevents, or reduces the frequency, rate or extent of epidermis development. GO:0021619 hypoglossal nerve maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021619 CN XII maturation A developmental process, independent of morphogenetic (shape) change, that is required for the hypoglossal nerve to attain its fully functional state. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue. GO:0070628 proteasome binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0070628 Interacting selectively and non-covalently with a proteasome, a large multisubunit protein complex that catalyzes protein degradation. GO:0070629 (1->4)-alpha-glucan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070629 1,4-alpha-glucan metabolism|1,4-alpha-D-glucan metabolism|alpha-1,4 glucan metabolic process|alpha-1,4 glucan metabolism|(1->4)-alpha-D-glucan metabolism The chemical reactions and pathways involving (1->4)-alpha-glucans, compounds composed of glucose residues linked by (1->4)-alpha-D-glucosidic bonds. GO:0070626 (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070626 MetaCyc:AICARSYN-RXN|EC:4.3.2.2|KEGG_REACTION:R04559|RHEA:23920 succino AMP-lyase activity|adenylosuccinate lyase activity|adenylosuccinase activity Catalysis of the reaction: (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate = fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. GO:0070627 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0070627 GO:0070624 negative regulation of thiamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070624 inhibition of thiamine biosynthetic process|negative regulation of thiamin biosynthetic process|down regulation of thiamine biosynthetic process|downregulation of thiamine biosynthetic process|negative regulation of thiamine anabolism|negative regulation of thiamine synthesis|down-regulation of thiamine biosynthetic process|negative regulation of thiamine biosynthesis|negative regulation of thiamine formation Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine. GO:0070625 zymogen granule exocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070625 The release of intracellular molecules contained within the zymogen granule by fusion of the granule with the plasma membrane of the oocyte, requiring calcium ions. GO:0070622 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070622 UDP-N-acetylglucosamine:lysosomal-enzyme N-acetylglucosamine-1-phosphotransferase complex|N-acetylglucosamine-1-phosphotransferase complex A protein complex that possesses UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity; the bovine complex contains disulfide-linked homodimers of 166- and 51-kDa subunits and two identical, noncovalently associated 56-kDa subunits. GO:0055003 cardiac myofibril assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055003 heart myofibril assembly|cardiac myofibril morphogenesis|cardiac myofibril development The process whose specific outcome is the progression of the cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells. UBERON:0003403 skin of forearm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003403 lower arm skin|lower segment of arm skin|forearm skin|skin of zeugopod of arm|skin of lower arm|skin of antebrachial region|skin of lower segment of arm A zone of skin that is part of a lower arm [Automatically generated definition]. GO:0021611 facial nerve formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021611 CN VII formation|CN VII biosynthesis The process that gives rise to the facial nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities. GO:0070623 regulation of thiamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070623 regulation of thiamine anabolism|regulation of thiamine synthesis|regulation of thiamine formation|regulation of thiamin biosynthetic process|regulation of thiamine biosynthesis Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine. GO:0021612 facial nerve structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021612 CN VII structural organization|facial nerve structural organisation The process that contributes to the act of creating the structural organization of the facial nerve. This process pertains to the physical shaping of a rudimentary structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities. UBERON:0003404 lobar bronchus of right lung biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003404 right lung lobar bronchus|right lung secondary bronchus|secondary bronchus of right lung|right lobar bronchus A lobar bronchus that is part of a right lung [Automatically generated definition]. GO:0055004 atrial cardiac myofibril assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055004 atrial cardiac myofibril development|atrial heart myofibril development The process whose specific outcome is the progression of the atrial cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells. GO:0070620 EGFR-Grb2-Sos complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070620 Egfr-Grb2-mSos1 complex, EGF stimulated A protein complex that contains the epidermal growth factor receptor (EGFR), Grb2 and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway. GO:0055005 ventricular cardiac myofibril assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055005 ventricular cardiac myofibril development|ventricular heart myofibril development The process whose specific outcome is the progression of the ventricular cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells. GO:0021613 facial nerve maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021613 CN VII maturation A developmental process, independent of morphogenetic (shape) change, that is required for the facial nerve to attain its fully functional state. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities. GO:0021614 glossopharyngeal nerve maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021614 CN IX maturation A developmental process, independent of morphogenetic (shape) change, that is required for the glossopharyngeal nerve to attain its fully functional state. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion. GO:0070621 EGFR-Shc-Grb2-Sos complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070621 A protein complex that contains the epidermal growth factor receptor (EGFR), Grb2, the adaptor protein SHC and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway. GO:0055006 cardiac cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055006 cardiocyte development|heart cell development The process whose specific outcome is the progression of a cardiac cell over time, from its formation to the mature state. A cardiac cell is a cell that will form part of the cardiac organ of an individual. GO:0021615 glossopharyngeal nerve morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021615 CN IX morphogenesis The process in which the anatomical structure of the glossopharyngeal nerve is generated and organized. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion. GO:0021616 glossopharyngeal nerve formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021616 CN IX formation|CN IX biosynthesis The process that gives rise to the glossopharyngeal nerve. This process pertains to the initial formation of a structure from unspecified parts. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion. CHEBI:71285 organophosphonate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71285 GO:0055001 muscle cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055001 The process whose specific outcome is the progression of a muscle cell over time, from its formation to the mature structure. Muscle cell development does not include the steps involved in committing an unspecified cell to the muscle cell fate. GO:0021617 glossopharyngeal nerve structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021617 CN IX structural organization|glossopharyngeal nerve structural organisation The process that contributes to the act of creating the structural organization of the glossopharyngeal nerve. This process pertains to the physical shaping of a rudimentary structure. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion. CHEBI:71286 3-nitrotyramine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71286 CHEBI:71287 4-hydroxy-3-nitrophenylacetaldehyde(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71287 GO:0021618 hypoglossal nerve morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021618 CN XII morphogenesis The process in which the anatomical structure of the hypoglossal nerve is generated and organized. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue. GO:0055002 striated muscle cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055002 The process whose specific outcome is the progression of a striated muscle cell over time, from its formation to the mature structure. Striated muscle cells contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. GO:0045691 regulation of embryo sac central cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045691 regulation of female gametophyte central cell differentiation Any process that modulates the frequency, rate or extent of female gametophyte central cell differentiation. GO:0045692 negative regulation of embryo sac central cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045692 down-regulation of female gametophyte central cell differentiation|negative regulation of female gametophyte central cell differentiation|inhibition of female gametophyte central cell differentiation|down regulation of female gametophyte central cell differentiation|downregulation of female gametophyte central cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of embryo sac central cell differentiation. GO:0045690 positive regulation of antipodal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045690 stimulation of antipodal cell differentiation|up-regulation of antipodal cell differentiation|activation of antipodal cell differentiation|up regulation of antipodal cell differentiation|upregulation of antipodal cell differentiation Any process that activates or increases the frequency, rate or extent of antipodal cell differentiation. CHEBI:356010 5-aminopentanoic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_356010 GO:0055018 regulation of cardiac muscle fiber development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055018 regulation of cardiac muscle fibre development|regulation of heart muscle fiber development Any process that modulates the frequency, rate or extent of cardiac muscle fiber development. GO:0055019 negative regulation of cardiac muscle fiber development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055019 down-regulation of cardiac muscle fiber development|downregulation of cardiac muscle fiber development|down regulation of cardiac muscle fiber development|inhibition of cardiac muscle fiber development|negative regulation of heart muscle fiber development|negative regulation of cardiac muscle fibre development Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle fiber development. GO:0045699 positive regulation of synergid differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045699 up regulation of synergid differentiation|positive regulation of synergid cell differentiation|upregulation of synergid differentiation|stimulation of synergid differentiation|up-regulation of synergid differentiation|activation of synergid differentiation Any process that activates or increases the frequency, rate or extent of synergid cell differentiation. GO:0045697 regulation of synergid differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045697 regulation of synergid cell differentiation Any process that modulates the frequency, rate or extent of synergid cell differentiation. GO:0045698 negative regulation of synergid differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045698 downregulation of synergid differentiation|down regulation of synergid differentiation|inhibition of synergid differentiation|negative regulation of synergid cell differentiation|down-regulation of synergid differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of synergid cell differentiation. GO:0045695 negative regulation of embryo sac egg cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045695 down regulation of female gametophyte egg cell differentiation|downregulation of female gametophyte egg cell differentiation|down-regulation of female gametophyte egg cell differentiation|negative regulation of female gametophyte egg cell differentiation|inhibition of female gametophyte egg cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of embryo sac egg cell differentiation. GO:0045696 positive regulation of embryo sac egg cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045696 upregulation of female gametophyte egg cell differentiation|up regulation of female gametophyte egg cell differentiation|activation of female gametophyte egg cell differentiation|positive regulation of female gametophyte egg cell differentiation|stimulation of female gametophyte egg cell differentiation|up-regulation of female gametophyte egg cell differentiation Any process that activates or increases the frequency, rate or extent of embryo sac egg cell differentiation. GO:0045693 positive regulation of embryo sac central cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045693 positive regulation of female gametophyte central cell differentiation|stimulation of female gametophyte central cell differentiation|up-regulation of female gametophyte central cell differentiation|upregulation of female gametophyte central cell differentiation|up regulation of female gametophyte central cell differentiation|activation of female gametophyte central cell differentiation Any process that activates or increases the frequency, rate or extent of embryo sac central cell differentiation. GO:0045694 regulation of embryo sac egg cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045694 regulation of female gametophyte egg cell differentiation Any process that modulates the frequency, rate or extent of embryo sac egg cell differentiation. GO:0021608 accessory nerve formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021608 CN XI biosynthesis|CN XI formation The process that gives rise to the accessory nerve. This process pertains to the initial formation of a structure from unspecified parts. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve. CHEBI:36885 20-oxo steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36885 GO:0021609 accessory nerve structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021609 CN XI structural organization|accessory nerve structural organisation The process that contributes to the act of creating the structural organization of the accessory nerve This process pertains to the physical shaping of a rudimentary structure. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve. CHEBI:36886 21-oxo steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36886 CHEBI:36883 6-oxo steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36883 CHEBI:36884 26-oxo steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36884 GO:0070659 inner ear sensory epithelium regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070659 The regrowth of lost or destroyed inner ear sensory epithelia. GO:0070657 neuromast regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070657 The regrowth of a neuromast following its loss or destruction. CHEBI:36887 18-oxo steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36887 GO:0070658 neuromast hair cell differentiation involved in neuromast regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070658 Differentiation of new neuromast sensory hair cells to replace those lost or destroyed by injury. GO:0055014 atrial cardiac muscle cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055014 atrial heart muscle development|atrial cardiomyocyte development The process whose specific outcome is the progression of an atrial cardiac muscle cell over time, from its formation to the mature state. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The atrium is the part of the heart that receives blood into the organ. GO:0070655 mechanosensory epithelium regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070655 The regrowth of lost or destroyed mechanosensory epithelia. GO:0021600 abducens nerve structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021600 abducens nerve structural organisation|CN VI structural organization The process that contributes to the act of creating the structural organization of the abducens nerve. This process pertains to the physical shaping of a rudimentary structure. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye. GO:0021601 abducens nerve maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021601 CN VI maturation A developmental process, independent of morphogenetic (shape) change, that is required for the abducens nerve to attain its fully functional state. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye. GO:0070656 mechanoreceptor differentiation involved in mechanosensory epithelium regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070656 Differentiation of new mechanoreceptors to replace those lost or destroyed by injury. GO:0055015 ventricular cardiac muscle cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055015 ventricular heart muscle cell development|ventricular cardiomyocyte development The process whose specific outcome is the progression of a ventricular cardiac muscle cell over time, from its formation to the mature state. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The ventricle is the part of the heart that pumps blood out of the organ. CHEBI:71293 homopolysaccharide derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71293 GO:0070653 high-density lipoprotein particle receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070653 high-density lipoprotein receptor binding|HDL receptor binding Interacting selectively and non-covalently with a high-density lipoprotein receptor. GO:0055016 hypochord development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055016 subnotochordal rod development The process whose specific outcome is the progression of the hypochord over time, from its formation to the mature structure. The hypochord is a transient rod-like structure in the embryos of fish, lampreys and amphibians that is located immediately ventral to the notochord. The hypochord may play a role in positioning the dorsal aorta. GO:0021602 cranial nerve morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021602 The process in which the anatomical structure of the cranial nerves are generated and organized. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. GO:0055017 cardiac muscle tissue growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055017 heart muscle growth The increase in size or mass of a cardiac muscle, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another. GO:0070654 sensory epithelium regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070654 The regrowth of a sensory epithelium following its loss or destruction. GO:0021603 cranial nerve formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021603 The process that gives rise to the cranial nerves. This process pertains to the initial formation of a structure from unspecified parts. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. GO:0070651 nonfunctional rRNA decay biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070651 NRD An rRNA catabolic process that results in the targeted detection and degradation of aberrant rRNAs contained within translationally defective ribosomes, thereby acting as a quality-control system. GO:0055010 ventricular cardiac muscle tissue morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055010 ventricular heart muscle morphogenesis|cardiac ventricle muscle morphogenesis The process in which the anatomical structures of cardiac ventricle muscle is generated and organized. GO:0021604 cranial nerve structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021604 cranial nerve structural organisation The process that contributes to the act of creating the structural organization of the cranial nerves. This process pertains to the physical shaping of a rudimentary structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. GO:0055011 atrial cardiac muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055011 atrial heart muscle cell differentiation|atrial cardiomyocyte differentiation The process in which a relatively unspecialized cell acquires specialized features of a cardiac muscle cell in the atrium. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The atrium is the part of the heart that receives blood into the organ. GO:0070652 HAUS complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070652 HAUS augmin complex A protein complex that localizes to interphase centrosomes and to mitotic spindle tubules and regulates mitotic spindle assembly and centrosome integrity; in human, the complex consists of eight subunits, some of which are homologous to subunits of the Drosophila Augmin complex. GO:0021605 cranial nerve maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021605 A developmental process, independent of morphogenetic (shape) change, that is required for a cranial nerve to attain its fully functional state. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. CHEBI:71296 fructan derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71296 CHEBI:36882 (3S)-citramalyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36882 GO:0021606 accessory nerve maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021606 CN XI maturation|spinal accessory nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the accessory nerve to attain its fully functional state. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve. GO:0055012 ventricular cardiac muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055012 ventricular cardiomyocyte differentiation|ventricular heart muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a ventricular cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The ventricle is the part of the heart that pumps blood out of the organ. GO:0021607 accessory nerve morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021607 CN XI morphogenesis The process in which the anatomical structure of the accessory nerve is generated and organized. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve. GO:0070650 actin filament bundle distribution biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070650 Any cellular process that establishes the spatial arrangement of actin filament bundles within the cell. GO:0055013 cardiac muscle cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055013 heart muscle cell development|cardiomyocyte cell development The process whose specific outcome is the progression of a cardiac muscle cell over time, from its formation to the mature state. CHEBI:71298 glucan derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71298 CHEBI:36880 organic radical ion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36880 CHEBI:22256 adenosine phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22256 GO:0055029 nuclear DNA-directed RNA polymerase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0055029 A protein complex, located in the nucleus, that possesses DNA-directed RNA polymerase activity. OBO:GOCHE_37527 substance with acid role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_37527 CHEBI:22251 adenosine bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22251 CHEBI:36896 monoatomic bromine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36896 CHEBI:36897 monoatomic iodine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36897 CHEBI:36894 elemental bromine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36894 GO:0055020 positive regulation of cardiac muscle fiber development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055020 stimulation of cardiac muscle fiber development|up-regulation of cardiac muscle fiber development|activation of cardiac muscle fiber development|positive regulation of cardiac muscle fibre development|up regulation of cardiac muscle fiber development|positive regulation of heart muscle fiber development|upregulation of cardiac muscle fiber development Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle fiber development. CHEBI:36895 monoatomic fluorine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36895 GO:0070648 formin-nucleated actin cable biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070648 An actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins. In fungal cells, myosin motors transport cargo along actin cables toward sites of polarized cell growth; actin cables may play a similar role in pollen tube growth. GO:0070649 formin-nucleated actin cable assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070649 formin-nucleated actin cable formation The aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins. GO:0070646 protein modification by small protein removal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070646 A protein modification process in which one or more covalently attached groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are removed from a target protein. GO:0070647 protein modification by small protein conjugation or removal biolink:BiologicalProcess go-plus goslim_drosophila|goslim_pombe|goslim_yeast http://purl.obolibrary.org/obo/GO_0070647 A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to or removed from a target protein. GO:0055025 positive regulation of cardiac muscle tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055025 up regulation of cardiac muscle development|positive regulation of heart muscle development|upregulation of cardiac muscle development|stimulation of cardiac muscle development|up-regulation of cardiac muscle development|activation of cardiac muscle development Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle tissue development. GO:0070644 vitamin D response element binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070644 VDRE binding Interacting selectively and non-covalently with the vitamin D response element (VDRE), a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum. GO:0055026 negative regulation of cardiac muscle tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055026 downregulation of cardiac muscle development|negative regulation of heart muscle development|down regulation of cardiac muscle development|inhibition of cardiac muscle development|down-regulation of cardiac muscle development Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle tissue development. GO:0070645 Ubisch body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070645 orbicule A small, granular structure that is found in the extracellular matrix of cell of the secretory tapetal layer that surrounds developing pollen grains. Ubisch bodies have a sporopollenin coat, are attached to the peritapetal wall, and may play a role in pollen development. CHEBI:46209 L-tyrosinal biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46209 GO:0070642 vitamin D5 metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070642 vitamin D5 metabolism The chemical reactions and pathways involving vitamin D5, (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,4S)-4-ethyl-1,5-dimethylhexyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylene-1-cyclohexanol. GO:0055027 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0055027 GO:0070643 vitamin D 25-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070643 cholecalciferol 25-hydroxylase activity|vitamin D2 25-hydroxylase activity|calciferol 25-hydroxylase activity|ergocalciferol 25-hydroxylase activity Catalysis of the hydroxylation of C-25 of any form of vitamin D. GO:0055028 cortical microtubule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0055028 Arrays of microtubules underlying and connected to the plasma membrane in the cortical cytosol. GO:0070640 vitamin D3 metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070640 cholecalciferol metabolic process|calciol metabolic process|vitamin D3 metabolism The chemical reactions and pathways involving vitamin D3, (3S,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol. CHEBI:36892 elemental fluorine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36892 GO:0055021 regulation of cardiac muscle tissue growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055021 Any process that modulates the frequency, rate or extent of cardiac muscle growth. GO:0055022 negative regulation of cardiac muscle tissue growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055022 down regulation of cardiac muscle growth|downregulation of cardiac muscle growth|negative regulation of heart muscle growth|down-regulation of cardiac muscle growth|inhibition of cardiac muscle growth Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle growth. GO:0070641 vitamin D4 metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070641 vitamin D4 metabolism The chemical reactions and pathways involving vitamin D4, (3S,5Z,7E)-9,10-secoergosta-5,7,10(19)-trien-3-ol. CHEBI:36893 elemental iodine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36893 GO:0055023 positive regulation of cardiac muscle tissue growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055023 upregulation of cardiac muscle growth|positive regulation of heart muscle growth|up regulation of cardiac muscle growth|activation of cardiac muscle growth|stimulation of cardiac muscle growth|up-regulation of cardiac muscle growth Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle growth. GO:0055024 regulation of cardiac muscle tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0055024 regulation of heart muscle development Any process that modulates the frequency, rate or extent of cardiac muscle tissue development. CHEBI:36891 diatomic iodine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36891 GO:0031061 negative regulation of histone methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031061 down-regulation of histone methylation|inhibition of histone methylation|down regulation of histone methylation|downregulation of histone methylation Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of methyl groups to histones. GO:0031062 positive regulation of histone methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031062 up regulation of histone methylation|activation of histone methylation|stimulation of histone methylation|up-regulation of histone methylation|upregulation of histone methylation Any process that activates or increases the frequency, rate or extent of the covalent addition of methyl groups to histones. CHEBI:85800 (R)-(2-chloro-5-oxo-2,5-dihydro-2-furyl)acetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85800 GO:0031060 regulation of histone methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031060 Any process that modulates the frequency, rate or extent of the covalent addition of methyl groups to histones. CHEBI:85801 heparosan D-glucuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85801 CHEBI:85802 heparosan L-iduronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85802 CHEBI:85803 (R)-ethylmalonyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85803 CHEBI:85804 UDP-4-dehydro-6-deoxy-alpha-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85804 CHEBI:85805 D-glucaro-1,4-lactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85805 GO:0031069 hair follicle morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031069 The process in which the anatomical structures of the hair follicle are generated and organized. CHEBI:85806 N,1-dipalmitoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85806 GO:0031067 negative regulation of histone deacetylation at centromere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031067 down regulation of histone deacetylation at centromere|downregulation of histone deacetylation at centromere|down-regulation of histone deacetylation at centromere|inhibition of histone deacetylation at centromere Any process that stops, prevents, or reduces the frequency, rate or extent of the removal of acetyl groups to histones in centromeric DNA. CHEBI:85808 N,1-dipalmitoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85808 GO:0031068 positive regulation of histone deacetylation at centromere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031068 upregulation of histone deacetylation at centromere|up regulation of histone deacetylation at centromere|activation of histone deacetylation at centromere|stimulation of histone deacetylation at centromere|up-regulation of histone deacetylation at centromere Any process that activates or increases the frequency, rate or extent of the removal of acetyl groups from histones in centromeric DNA. GO:0031065 positive regulation of histone deacetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031065 upregulation of histone deacetylation|up regulation of histone deacetylation|activation of histone deacetylation|stimulation of histone deacetylation|up-regulation of histone deacetylation Any process that activates or increases the frequency, rate or extent of the removal of acetyl groups from histones. CHEBI:85809 5alpha-androstane-3beta,6alpha,17beta-triol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85809 GO:0031066 regulation of histone deacetylation at centromere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031066 Any process that modulates the frequency, rate or extent of the removal of acetyl groups from histones in centromeric DNA. GO:0031063 regulation of histone deacetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031063 Any process that modulates the frequency, rate or extent of the removal of acetyl groups from histones. GO:0031064 negative regulation of histone deacetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031064 down regulation of histone deacetylation|downregulation of histone deacetylation|down-regulation of histone deacetylation|inhibition of histone deacetylation Any process that stops, prevents, or reduces the frequency, rate or extent of the removal of acetyl groups from histones. RO:0040036 has anatomical participant biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0040036 RO:0040036 p has anatomical participant c iff p has participant c, and c is an anatomical entity GO:0031050 dsRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031050 dsRNA fragmentation|double-stranded RNA fragmentation Cleavage of double-stranded RNA molecules by an RNaseIII-family enzyme to produce small RNAs (generally 20-30 nucleotides, depending on species) with biological function. GO:0031051 scnRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031051 scnRNA production Cleavage of noncoding, double-stranded RNAs transcribed from the micronuclear genome to produce scnRNAs, small RNAs (~28 nucleotides) that direct the deletion of micronuclear-limited sequences from the developing macronuclear genome. GO:0031058 positive regulation of histone modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031058 up regulation of histone modification|upregulation of histone modification|stimulation of histone modification|up-regulation of histone modification|activation of histone modification Any process that activates or increases the frequency, rate or extent of the covalent alteration of a histone. GO:0031059 histone deacetylation at centromere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031059 The removal of acetyl groups from histones in centromeric DNA. GO:0031056 regulation of histone modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031056 Any process that modulates the frequency, rate or extent of the covalent alteration of a histone. GO:0031057 negative regulation of histone modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031057 down-regulation of histone modification|downregulation of histone modification|down regulation of histone modification|inhibition of histone modification Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of a histone. GO:0031054 pre-miRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031054 pre-microRNA processing Any process involved in the conversion of a pre-microRNA transcript into a mature microRNA molecule. GO:0031055 chromatin remodeling at centromere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031055 Dynamic structural changes in centromeric DNA. GO:0031052 chromosome breakage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031052 establishment or maintenance of heterochromatin architecture Regulated cleavage of the developing macronuclear genome at a limited number of chromosome breakage sites (CBS). The macronuclear destined segment (MDS) sequence adjacent to the CBS (or separated from it by a BES) receives a macronuclear telomere following chromosome breakage. GO:0031053 primary miRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031053 primary microRNA processing|pri-miRNA processing Any process involved in the conversion of a primary microRNA transcript into a pre-microRNA molecule. GO:0031049 programmed DNA elimination biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0031049 The DNA metabolic process in which micronuclear-limited sequences, internal eliminated sequences (IES) and breakage eliminated sequences (BES) are removed from the developing macronucleus (anlage) of a ciliate. CHEBI:141588 phosphatidylethanolamine 36:2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_141588 GO:0006089 lactate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006089 2-hydroxypropanoate metabolism|lactate metabolism|alpha-hydroxypropionate metabolism|alpha-hydroxypropionate metabolic process|2-hydroxypropanoate metabolic process The chemical reactions and pathways involving lactate, the anion of lactic acid. GO:0006087 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006087 GO:0006088 obsolete acetate to acetyl-CoA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006088 acetate to acetyl-CoA OBSOLETE. (Was not defined before being made obsolete). GO:0006085 acetyl-CoA biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006085 MetaCyc:PWY-5173 acetyl-CoA formation|acetyl-CoA anabolism|acetyl-CoA biosynthesis|acetyl-CoA synthesis The chemical reactions and pathways resulting in the formation of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated. GO:0006086 acetyl-CoA biosynthetic process from pyruvate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006086 MetaCyc:PYRUVDEHYD-PWY acetyl-CoA synthesis from pyruvate|acetyl-CoA formation from pyruvate|pyruvate dehydrogenase pathway|acetyl-CoA anabolism from pyruvate The chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate. GO:0006094 gluconeogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006094 Wikipedia:Gluconeogenesis|MetaCyc:GLUCONEO-PWY glucose biosynthesis|glucose biosynthetic process The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol. GO:0031040 micronucleus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031040 Wikipedia:Micronucleus A membrane-bounded organelle of ciliated protozoan cells that contains a diploid copy of the cell's complete genome. Sections of contiguous sequence in the macronucleus are often interrupted by internal eliminated sequences (IES), and may be permuted, in micronuclei. Genic transcription is not found in micronuclei. Some ciliate species may contain multiple micronuclei per cell. CHEBI:85820 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85820 GO:0006095 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006095 GO:0006092 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006092 GO:0006093 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0006093 GO:0006090 pyruvate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006090 MetaCyc:P41-PWY|Wikipedia:Pyruvic_acid pyruvate dehydrogenase bypass|pyruvate metabolism The chemical reactions and pathways involving pyruvate, 2-oxopropanoate. GO:0006091 generation of precursor metabolites and energy biolink:BiologicalProcess go-plus goslim_plant|goslim_pir|goslim_drosophila|goslim_metagenomics|goslim_generic|goslim_pombe|goslim_chembl|goslim_yeast|goslim_candida http://purl.obolibrary.org/obo/GO_0006091 metabolic energy generation|energy pathways|intermediary metabolism The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances. GO:0031047 gene silencing by RNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031047 RNA-mediated gene silencing Any process in which RNA molecules inactivate expression of target genes. GO:0031048 heterochromatin assembly by small RNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031048 RNA-mediated TGS|RNA interference-like chromatin silencing|RNA-mediated chromatin silencing|RNAi-directed chromatin silencing|RNAi-like chromatin silencing|chromatin silencing by small RNA|small RNA-mediated heterochromatic silencing|heterochromatin formation involved in chromatin silencing by small RNA|RNA-mediated transcriptional silencing|small RNA-mediated heterochromatin formation|heterochromatin assembly involved in chromatin silencing by small RNA Assembly of heterochromatin, directed by small RNAs sharing sequence identity to the repressed region. GO:0031045 dense core granule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031045 NIF_Subcellular:sao772007592 dense core vesicle Electron-dense organelle with a granular internal matrix; contains proteins destined to be secreted. CHEBI:85829 CDP-1-stearoyl-2-arachidonoyl-sn-glycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85829 GO:0031046 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031046 GO:0031043 O-glycan processing, core 7 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031043 The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 7 O-glycan structure, GalNAc-alpha-(1->6)-GalNAc. GO:0031044 O-glycan processing, core 8 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031044 The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 8 O-glycan structure, Gal-alpha-(1->3)-GalNAc. GO:0031041 O-glycan processing, core 5 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031041 The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 5 O-glycan structure, GalNAc-alpha-(1->3)-GalNAc. GO:0031042 O-glycan processing, core 6 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031042 The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 6 O-glycan structure, GlcNAc-beta-(1->6)-GalNAc. GO:0031038 myosin II filament organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031038 myosin II polymerization or depolymerization|myosin II filament assembly or disassembly|myosin II filament organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a bipolar filament composed of myosin II molecules. GO:0031039 macronucleus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031039 Wikipedia:Macronucleus A membrane-bounded organelle of ciliated protozoan cells that contains polyploid copies of a portion of the cell's complete genome. Transcription of genes occurs in macronuclei. Some ciliate species may contain multiple macronuclei per cell. GO:0006098 pentose-phosphate shunt biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006098 MetaCyc:PENTOSE-P-PWY|KEGG_PATHWAY:00030|Reactome:R-HSA-71336|Wikipedia:Pentose_phosphate_pathway pentose phosphate pathway|hexose monophosphate pathway|pentose phosphate shunt|pentose-phosphate pathway The metabolic process in which glucose-6-phosphate is oxidized to form carbon dioxide (CO2) and ribulose 5-phosphate, coupled to reduction of NADP+ to NADPH; ribulose 5-P then enters a series of reactions that can yield biosynthetic precursors (ribose-5-phosphate and erythrose-4-phosphate) and glycolytic intermediates (fructose-6-phosphate and glyceraldehyde-3-phosphate). GO:0006099 tricarboxylic acid cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006099 MetaCyc:P42-PWY|MetaCyc:TCA|MetaCyc:P105-PWY|Wikipedia:Tricarboxylic_acid_cycle citric acid cycle|TCA cycle|Krebs cycle A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle. GO:0006096 glycolytic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006096 MetaCyc:GLYCOLYSIS-VARIANTS Embden-Meyerhof-Parnas pathway|glycolysis|anaerobic glycolysis|Embden-Meyerhof pathway|modifed Embden-Meyerhof pathway The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules. GO:0006097 glyoxylate cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006097 Wikipedia:Glyoxylate_cycle|MetaCyc:GLYOXYLATE-BYPASS glyoxylate bypass A modification of the TCA cycle occurring in some plants and microorganisms, in which isocitrate is cleaved to glyoxylate and succinate. Glyoxylate can then react with acetyl-CoA to form malate. CHEBI:85810 androst-5-ene-3beta,7alpha,17beta-triol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85810 CHEBI:85811 (6S)-5,6,7,8-tetrahydropteroic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85811 CHEBI:85812 Cer(d42:2) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85812 CHEBI:85816 (3beta,5alpha,7alpha)-3,7-dihydroxyandrostan-17-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_85816 GO:0031036 myosin II filament assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031036 myosin II polymerization The formation of a bipolar filament composed of myosin II molecules. GO:0031037 myosin II filament disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031037 myosin II depolymerization The disassembly of a bipolar filament composed of myosin II molecules. GO:0031034 myosin filament assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031034 myosin polymerization The aggregation, arrangement and bonding together of a filament composed of myosin molecules. GO:0031035 myosin filament disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031035 myosin depolymerization The disassembly of a filament composed of myosin molecules. GO:0031032 actomyosin structure organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031032 actomyosin structure organisation|actomyosin structure organization and biogenesis|actomyosin organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. The myosin may be organized into filaments. GO:0031033 myosin filament organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031033 myosin filament organisation|myosin polymerization or depolymerization|myosin filament assembly or disassembly A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a filament composed of myosin molecules. GO:0031030 negative regulation of septation initiation signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031030 down-regulation of septation initiation signaling|downregulation of septation initiation signaling|negative regulation of septation initiation network|down regulation of septation initiation signaling|inhibition of septation initiation signaling|negative regulation of septation initiation signalling|negative regulation of septation initiation signaling cascade Any process that stops, prevents, or reduces the frequency, rate or extent of septation initiation signaling. GO:0031031 positive regulation of septation initiation signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031031 positive regulation of septation initiation signaling cascade|up regulation of septation initiation signaling|positive regulation of septation initiation signalling|upregulation of septation initiation signaling|positive regulation of septation initiation network|stimulation of septation initiation signaling|up-regulation of septation initiation signaling|activation of septation initiation signaling Any process that activates or increases the frequency, rate or extent of septation initiation signaling. GO:0031029 regulation of septation initiation signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031029 regulation of septation initiation signaling cascade|regulation of septation initiation signalling|regulation of septation initiation network Any process that modulates the frequency, rate or extent of septation initiation signaling. GO:0031027 glutamate synthase complex (NADH) biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031027 A protein complex that in yeast consists of a large and a small subunit. Possesses glutamate synthase (NADH) activity. GO:0031028 septation initiation signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031028 septation initiation network|septation initiation signalling|septation initiation signaling cascade|SIN The series of molecular signals, mediated by the small GTPase Ras, that results in the initiation of contraction of the contractile ring, at the beginning of cytokinesis and cell division by septum formation. The pathway coordinates chromosome segregation with mitotic exit and cytokinesis. GO:0006069 ethanol oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006069 An ethanol metabolic process in which ethanol is converted to acetyl-CoA via acetaldehyde and acetate. GO:0006067 ethanol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006067 ethanol metabolism The chemical reactions and pathways involving ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation. GO:0006068 ethanol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006068 ethanol catabolism|ethanol degradation|ethanol breakdown The chemical reactions and pathways resulting in the breakdown of ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation. CHEBI:61870 monounsaturated fatty aldehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61870 GO:0006065 UDP-glucuronate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006065 MetaCyc:PWY-4841 UDP-glucuronate biosynthesis|UDP-glucuronate anabolism|UDP-glucuronate synthesis|UDP-glucuronate formation The chemical reactions and pathways resulting in the formation of UDP-glucuronate, a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate. GO:0006066 alcohol metabolic process biolink:BiologicalProcess go-plus goslim_pir|goslim_drosophila http://purl.obolibrary.org/obo/GO_0006066 alcohol metabolism The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom. GO:0006063 uronic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006063 uronic acid metabolism The chemical reactions and pathways involving uronic acid, any monocarboxylic acid formally derived by oxidizing to a carboxyl group the terminal hydroxymethylene group of either an aldose with four or more carbon atoms in the molecule, or of any glycoside derived from such an aldose. GO:0006064 glucuronate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006064 glucuronate catabolism|glucuronate degradation|glucuronate breakdown The chemical reactions and pathways resulting in the breakdown of glucuronate, any salt or ester of glucuronic acid. CHEBI:85841 CDP-1-stearoyl-2-oleoyl-sn-glycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85841 GO:0006072 glycerol-3-phosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006072 glycerol-3-phosphate metabolism The chemical reactions and pathways involving glycerol-3-phosphate, a phosphoric monoester of glycerol. GO:0006073 cellular glucan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006073 cellular glucan metabolism The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues, occurring at the level of an individual cell. GO:0006070 octanol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006070 octanol metabolism The chemical reactions and pathways involving octanol, the 8-carbon alcohol with the formula C8H17OH. GO:0006071 glycerol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006071 MetaCyc:GLYCEROLMETAB-PWY glycerol metabolism The chemical reactions and pathways involving glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids. CHEBI:61873 2-demethylmenaquinol-8 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61873 CHEBI:85846 CDP-1-stearoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85846 CHEBI:85848 CDP-1,2-dilinoleoyl-sn-glycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85848 GO:0031025 equatorial microtubule organizing center disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031025 equatorial microtubule organising center disassembly The process in which the equatorial microtubule organizing center is disassembled at the end of mitosis. GO:0031026 glutamate synthase complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0031026 A complex that possesses glutamate synthase activity. GO:0031023 microtubule organizing center organization biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0031023 microtubule organising center organisation|microtubule organizing center organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microtubule organizing center, a structure from which microtubules grow. GO:0031024 interphase microtubule organizing center assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031024 interphase microtubule organizing centre assembly|interphase microtubule organizing center biogenesis|interphase microtubule organising center formation|interphase microtubule organising center biosynthesis The aggregation, arrangement and bonding together of a set of components, including gamma-tubulin and other proteins, to form an interphase microtubule organizing center. GO:0031021 interphase microtubule organizing center biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031021 iMTOC|interphase microtubule organising center|interphase MTOC A microtubule organizing center found in interphase cells, which organize a longitudinal array of three to five MT bundles from the nuclear envelope during interphase. Each MT bundle is composed of two to seven MTs arranged in an antiparallel configuration, with the dynamic MT plus ends extending toward the cell tips and stable minus ends near the nucleus. GO:0031022 nuclear migration along microfilament biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031022 nuclear migration, microfilament-mediated The directed movement of the nucleus along microfilaments within the cell, mediated by motor proteins. GO:0031020 plastid mRNA editing complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031020 plastid editosome An mRNA editing complex found in a plastid. GO:0021691 cerebellar Purkinje cell layer maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021691 A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar Purkinje cell layer to attain its fully functional state. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells. GO:0021692 cerebellar Purkinje cell layer morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021692 The process in which the anatomical structure of the cerebellar Purkinje cell layer is generated and organized. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells. GO:0021693 cerebellar Purkinje cell layer structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021693 cerebellar Purkinje cell layer structural organisation The process that contributes to the act of creating the structural organization of the cerebellar Purkinje cell layer. This process pertains to the physical shaping of a rudimentary structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells. CHEBI:71203 beta-D-Galp-(1->4)-beta-D-GlcpNAc-(1->3)-beta-D-Galp-(1->4)-beta-D-GlcpNAc biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71203 GO:0021694 cerebellar Purkinje cell layer formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021694 The process that gives rise to the cerebellar Purkinje cell layer. This process pertains to the initial formation of a structure from unspecified parts. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells. GO:0031018 endocrine pancreas development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031018 The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin. GO:0021695 cerebellar cortex development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021695 The process whose specific outcome is the progression of the cerebellar cortex over time, from its formation to the mature structure. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function. GO:0031019 mitochondrial mRNA editing complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031019 mitochondrial editosome An mRNA editing complex found in the mitochondrion. The best characterized example is that of Trypanosoma brucei, which catalyzes the insertion and deletion of uridylates. GO:0021696 cerebellar cortex morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021696 The process in which the anatomical structure of the cranial nerves are generated and organized. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function. GO:0021697 cerebellar cortex formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021697 The process that gives rise to the cerebellar cortex. This process pertains to the initial formation of a structure from unspecified parts. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function. GO:0031016 pancreas development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031016 Wikipedia:Pancreas The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. The pancreas is an endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating enzymes. CHEBI:71207 (2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71207 GO:0021698 cerebellar cortex structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021698 cerebellar cortex structural organisation The process that contributes to the act of creating the structural organization of the cerebellar cortex. This process pertains to the physical shaping of a rudimentary structure. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function. GO:0031017 exocrine pancreas development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031017 The process whose specific outcome is the progression of the exocrine pancreas over time, from its formation to the mature structure. The exocrine pancreas produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells. GO:0045600 positive regulation of fat cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045600 up regulation of fat cell differentiation|upregulation of fat cell differentiation|positive regulation of adipocyte differentiation|stimulation of fat cell differentiation|positive regulation of adipocyte cell differentiation|up-regulation of fat cell differentiation|activation of fat cell differentiation Any process that activates or increases the frequency, rate or extent of adipocyte differentiation. GO:0045601 regulation of endothelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045601 Any process that modulates the frequency, rate or extent of endothelial cell differentiation. CHEBI:71209 N-(cyanomethyl)glycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71209 GO:0006078 (1->6)-beta-D-glucan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006078 beta-1,6 glucan biosynthetic process|beta-1,6 glucan biosynthesis|1,6-beta-glucan anabolism|1,6-beta-glucan biosynthetic process|1,6-beta-glucan biosynthesis|1,6-beta-glucan synthesis|1,6-beta-glucan formation|beta-1,6 glucan anabolism|beta-1,6 glucan synthesis|beta-1,6 glucan formation The chemical reactions and pathways resulting in the formation of (1->6)-beta-D-glucans. GO:0006079 (1->6)-beta-D-glucan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006079 1,6-beta-D-glucan catabolic process|beta-1,6 glucan catabolism|beta-1,6 glucan degradation|beta-1,6 glucan breakdown|beta-1,6 glucan catabolic process|1,6-beta-D-glucan catabolism|1,6-beta-D-glucan degradation|1,6-beta-D-glucan breakdown The chemical reactions and pathways resulting in the breakdown of (1->6)-beta-D-glucans. GO:0006076 (1->3)-beta-D-glucan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006076 1,3-beta-D-glucan catabolic process|1,3-beta-glucan degradation|beta-1,3 glucan degradation|beta-1,3 glucan catabolism|1,3-beta-glucan breakdown|1,3-beta-glucan catabolism|beta-1,3 glucan breakdown|beta-1,3 glucan catabolic process The chemical reactions and pathways resulting in the breakdown of (1->3)-beta-D-glucans. GO:0006077 (1->6)-beta-D-glucan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006077 1,6-beta-glucan metabolic process|beta-1,6 glucan metabolism|beta-1,6 glucan metabolic process|1,6-beta-glucan metabolism The chemical reactions and pathways involving (1->6)-beta-D-glucans, compounds composed of glucose residues linked by (1->6)-beta-D-glucosidic bonds. GO:0006074 (1->3)-beta-D-glucan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006074 1,3-beta-D-glucan metabolic process|beta-1,3 glucan metabolic process|1,3-beta-glucan metabolic process|beta-1,3 glucan metabolism|1,3-beta-D-glucan metabolism The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds. GO:0006075 (1->3)-beta-D-glucan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006075 beta-1,3 glucan biosynthetic process|beta-1,3 glucan biosynthesis|1,3-beta-glucan biosynthesis|1,3-beta-glucan anabolism|beta-1,3 glucan anabolism|1,3-beta-glucan synthesis|1,3-beta-D-glucan biosynthetic process|beta-1,3 glucan synthesis|1,3-beta-glucan formation|beta-1,3 glucan formation The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds. GO:0021690 cerebellar molecular layer maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021690 A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar molecular layer to attain its fully functional state. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells. CHEBI:85830 CDP-1-palmitoyl-2-arachidonoyl-sn-glycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85830 GO:0045608 negative regulation of inner ear auditory receptor cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045608 down-regulation of auditory receptor cell differentiation|negative regulation of auditory receptor cell differentiation|negative regulation of auditory hair cell differentiation|downregulation of auditory receptor cell differentiation|down regulation of auditory receptor cell differentiation|inhibition of auditory receptor cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of auditory hair cell differentiation. GO:0006083 acetate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006083 acetate metabolism The chemical reactions and pathways involving acetate, the anion of acetic acid. GO:0045609 positive regulation of inner ear auditory receptor cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045609 up-regulation of auditory receptor cell differentiation|activation of auditory receptor cell differentiation|up regulation of auditory receptor cell differentiation|positive regulation of auditory receptor cell differentiation|positive regulation of auditory hair cell differentiation|upregulation of auditory receptor cell differentiation|stimulation of auditory receptor cell differentiation Any process that activates or increases the frequency, rate or extent of auditory hair cell differentiation. GO:0006084 acetyl-CoA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006084 acetyl-CoA metabolism|acetyl coenzyme A metabolic process|acetyl coenzyme A metabolism The chemical reactions and pathways involving acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis. GO:0045606 positive regulation of epidermal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045606 positive regulation of hypodermal cell differentiation|stimulation of epidermal cell differentiation|up-regulation of epidermal cell differentiation|activation of epidermal cell differentiation|up regulation of epidermal cell differentiation|upregulation of epidermal cell differentiation Any process that activates or increases the frequency, rate or extent of epidermal cell differentiation. GO:0006081 cellular aldehyde metabolic process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0006081 alkanal metabolic process|alkanal metabolism|aldehyde metabolism The chemical reactions and pathways involving aldehydes, any organic compound with the formula R-CH=O, as carried out by individual cells. GO:0006082 organic acid metabolic process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0006082 organic acid metabolism The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage. GO:0045607 regulation of inner ear auditory receptor cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045607 regulation of auditory receptor cell differentiation|regulation of auditory hair cell differentiation Any process that modulates the frequency, rate or extent of auditory hair cell differentiation. GO:0045604 regulation of epidermal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045604 regulation of hypodermal cell differentiation Any process that modulates the frequency, rate or extent of epidermal cell differentiation. GO:0006080 substituted mannan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006080 substituted mannan metabolism The chemical reactions and pathways involving a mannan backbone composed of D-mannose unites, substituted with D-glucose and/or D-galactose units. GO:0045605 negative regulation of epidermal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045605 negative regulation of hypodermal cell differentiation|down-regulation of epidermal cell differentiation|downregulation of epidermal cell differentiation|down regulation of epidermal cell differentiation|inhibition of epidermal cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal cell differentiation. CHEBI:85835 CDP-1,2-diarachidonoyl-sn-glycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85835 CHEBI:61887 N-acetylglycinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61887 GO:0045602 negative regulation of endothelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045602 down-regulation of endothelial cell differentiation|downregulation of endothelial cell differentiation|down regulation of endothelial cell differentiation|inhibition of endothelial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of endothelial cell differentiation. GO:0045603 positive regulation of endothelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045603 up-regulation of endothelial cell differentiation|activation of endothelial cell differentiation|up regulation of endothelial cell differentiation|upregulation of endothelial cell differentiation|stimulation of endothelial cell differentiation Any process that activates or increases the frequency, rate or extent of endothelial cell differentiation. GO:0031014 troponin T binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031014 Interacting selectively and non-covalently with troponin T, the tropomyosin-binding subunit of the troponin complex. GO:0021699 cerebellar cortex maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021699 A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar cortex to attain its fully functional state. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function. CHEBI:85838 CDP-1-stearoyl-2-linoleoyl-sn-glycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85838 GO:0031015 obsolete karyopherin docking complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031015 karyopherin docking complex|Asm4p-containing complex|nuclear pore subcomplex OBSOLETE. A subcomplex of the nuclear pore complex that interacts with karyopherin-cargo complexes; a well-characterized example in Saccharomyces contains Asm4p, Nup53p, and Nup170p. GO:0031012 extracellular matrix biolink:CellularComponent go-plus goslim_generic|goslim_chembl|goslim_pir|goslim_drosophila http://purl.obolibrary.org/obo/GO_0031012 NIF_Subcellular:nlx_subcell_20090513|Wikipedia:Extracellular_matrix proteinaceous extracellular matrix|matrisome A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues. GO:0031013 troponin I binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031013 Interacting selectively and non-covalently with troponin I, the inhibitory subunit of the troponin complex. GO:0031010 ISWI-type complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031010 Any nuclear protein complex that contains an ATPase subunit of the imitation switch (ISWI) family. ISWI ATPases are involved in assembling chromatin and in sliding and spacing nucleosomes to regulate transcription of nuclear RNA polymerases I, II, and III and also DNA replication, recombination and repair. GO:0031011 Ino80 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031011 INO80 chromatin remodeling complex A multisubunit protein complex that contains the Ino80p ATPase; exhibits chromatin remodeling activity and 3' to 5' DNA helicase activity. GO:0021680 cerebellar Purkinje cell layer development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021680 The process whose specific outcome is the progression of the cerebellar Purkinje cell layer over time, from its formation to the mature structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells. CHEBI:71211 (4-coumaroyl)acetyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71211 CHEBI:71212 prohormone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71212 GO:0021681 cerebellar granular layer development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021681 The process whose specific outcome is the progression of the cerebellar granule layer over time, from its formation to the mature structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer. CHEBI:71213 3-oxocyclopentanecarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71213 GO:0021682 nerve maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021682 A developmental process, independent of morphogenetic (shape) change, that is required for a nerve to attain its fully functional state. GO:0031009 plastid ADPG pyrophosphorylase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031009 An ADPG pyrophosphorylase complex found in a plastid. GO:0021683 cerebellar granular layer morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021683 The process in which the anatomical structure of the cerebellar granular layer is generated and organized. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer. CHEBI:71214 4-methoxy-4-oxo-3-phenylbutanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71214 GO:0021684 cerebellar granular layer formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021684 The process that gives rise to the cerebellar granule layer. This process pertains to the initial formation of a structure from unspecified parts. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer. GO:0031007 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031007 CHEBI:71215 (4-coumaroyl)acetyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_71215 GO:0021685 cerebellar granular layer structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021685 cerebellar granular layer structural organisation The process that contributes to the act of creating the structural organization of the cerebellar granule layer. This process pertains to the physical shaping of a rudimentary structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer. GO:0031008 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031008 GO:0021686 cerebellar granular layer maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021686 A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar granular layer to attain its fully functional state. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer. GO:0031005 filamin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0031005 filamin-3 binding|filamin-2 binding|filamin-1 binding|beta-filamin binding|ABPL binding|filamin B binding|filamin A binding|ABP-278/276 binding|filamin C binding|gamma-filamin binding|filamin-C binding|filamin-A binding|ABP-280 binding|alpha-filamin binding|filamin-B binding Interacting selectively and non-covalently with a filamin, any member of a family of high molecular mass cytoskeletal proteins that crosslink actin filaments to form networks and stress fibers. Filamins contain an amino-terminal alpha-actinin-like actin binding domain, which is followed by a rod-domain composed of 4 to 24 100-residue repetitive segments including a carboxy-terminal dimerization domain. GO:0006049 UDP-N-acetylglucosamine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006049 UDP-N-acetylglucosamine catabolism|UDP-N-acetylglucosamine degradation|UDP-N-acetylglucosamine breakdown The chemical reactions and pathways resulting in the breakdown of UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate. GO:0031006 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0031006 GO:0021687 cerebellar molecular layer morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021687 The process in which the anatomical structure of the cerebellar molecular layer is generated and organized. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells. GO:0045611 negative regulation of hemocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045611 down-regulation of hemocyte differentiation|negative regulation of arthropod blood cell differentiation|downregulation of hemocyte differentiation|down regulation of hemocyte differentiation|inhibition of hemocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of hemocyte differentiation. GO:0006047 UDP-N-acetylglucosamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006047 UDP-N-acetylglucosamine metabolism The chemical reactions and pathways involving UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate. GO:0006048 UDP-N-acetylglucosamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006048 MetaCyc:UDPNAGSYN-PWY UDP-N-acetylglucosamine anabolism|UDP-N-acetylglucosamine synthesis|UDP-N-acetylglucosamine formation|UDP-N-acetylglucosamine biosynthesis|UDP-GlcNAc biosynthesis|UDP-GlcNAc biosynthetic process The chemical reactions and pathways resulting in the formation of UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate. GO:0045612 positive regulation of hemocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045612 stimulation of hemocyte differentiation|activation of hemocyte differentiation|up-regulation of hemocyte differentiation|positive regulation of arthropod blood cell differentiation|up regulation of hemocyte differentiation|upregulation of hemocyte differentiation Any process that activates or increases the frequency, rate or extent of hemocyte differentiation. GO:0006045 N-acetylglucosamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006045 N-acetylglucosamine anabolism|N-acetylglucosamine biosynthesis|N-acetylglucosamine synthesis|N-acetylglucosamine formation The chemical reactions and pathways resulting in the formation of N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein. GO:0045610 regulation of hemocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045610 regulation of arthropod blood cell differentiation Any process that modulates the frequency, rate or extent of hemocyte differentiation. GO:0006046 N-acetylglucosamine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006046 N-acetylglucosamine degradation|N-acetylglucosamine breakdown|N-acetylglucosamine catabolism The chemical reactions and pathways resulting in the breakdown of N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein. GO:0006043 glucosamine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006043 MetaCyc:GLUAMCAT-PWY glucosamine degradation|glucosamine breakdown|chitosamine catabolic process|glucosamine catabolism|chitosamine catabolism The chemical reactions and pathways resulting in the breakdown of glucosamine (2-amino-2-deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin. GO:0006044 N-acetylglucosamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006044 N-acetylglucosamine metabolism The chemical reactions and pathways involving N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein. GO:0006041 glucosamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006041 chitosamine metabolic process|glucosamine metabolism|chitosamine metabolism The chemical reactions and pathways involving glucosamine (2-amino-2-deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin. CHEBI:61891 N(5)-methyl-L-glutamine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61891 GO:0006042 glucosamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006042 glucosamine anabolism|glucosamine synthesis|glucosamine biosynthesis|glucosamine formation|chitosamine biosynthesis|chitosamine biosynthetic process The chemical reactions and pathways resulting in the formation of glucosamine (2-amino-2-deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin. GO:0045619 regulation of lymphocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045619 regulation of lymphocyte development Any process that modulates the frequency, rate or extent of lymphocyte differentiation. GO:0006050 mannosamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006050 mannosamine metabolism The chemical reactions and pathways involving mannosomine, 2-amino-2-deoxymannose; the D-isomer is a constituent of neuraminic acids as well as mucolipids and mucoproteins. CHEBI:61896 N(omega),N(omega)-dimethyl-L-arginine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61896 GO:0006051 N-acetylmannosamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006051 N-acetylmannosamine metabolism The chemical reactions and pathways involving N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose. CHEBI:61897 N(omega),N(omega)-dimethyl-L-arginine(1+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61897 GO:0045617 negative regulation of keratinocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045617 down-regulation of keratinocyte differentiation|downregulation of keratinocyte differentiation|down regulation of keratinocyte differentiation|inhibition of keratinocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte differentiation. GO:0045618 positive regulation of keratinocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045618 stimulation of keratinocyte differentiation|up-regulation of keratinocyte differentiation|activation of keratinocyte differentiation|up regulation of keratinocyte differentiation|upregulation of keratinocyte differentiation Any process that activates or increases the frequency, rate or extent of keratinocyte differentiation. GO:0045615 positive regulation of plasmatocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045615 upregulation of plasmatocyte differentiation|stimulation of plasmatocyte differentiation|up-regulation of plasmatocyte differentiation|activation of plasmatocyte differentiation|up regulation of plasmatocyte differentiation Any process that activates or increases the frequency, rate or extent of plasmatocyte differentiation. GO:0045616 regulation of keratinocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045616 Any process that modulates the frequency, rate or extent of keratinocyte differentiation. GO:0045613 regulation of plasmatocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045613 Any process that modulates the frequency, rate or extent of plasmatocyte differentiation. CHEBI:61898 alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc(PP-Dol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61898 GO:0045614 negative regulation of plasmatocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045614 down-regulation of plasmatocyte differentiation|downregulation of plasmatocyte differentiation|down regulation of plasmatocyte differentiation|inhibition of plasmatocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of plasmatocyte differentiation. GO:0021688 cerebellar molecular layer formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021688 The process that gives rise to the cerebellar molecular layer. This process pertains to the initial formation of a structure from unspecified parts. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells. GO:0031003 actin tubule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031003 A cellular structure, approximately 13 nm in diameter, consisting of three actin filaments bundled together. GO:0021689 cerebellar molecular layer structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021689 cerebellar molecular layer structural organisation The process that contributes to the act of creating the structural organization of the cerebellar molecular layer. This process pertains to the physical shaping of a rudimentary structure. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells. GO:0031004 potassium ion-transporting ATPase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031004 Kdp system complex Protein complex that carries out the reaction: ATP + H2O + K+(out) = ADP + phosphate + K+(in). It is a high affinity potassium uptake system. The E. coli complex consists of 4 proteins: KdpA is the potassium ion translocase, KdpB is the ATPase, and KdpC and KdpF seem to be involved in assembly and stabilization of the complex. GO:0031001 response to brefeldin A biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031001 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brefeldin A stimulus. GO:0031002 actin rod biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0031002 A cellular structure consisting of parallel, hexagonally arranged actin tubules, comprising filamentous actin and associated proteins. Actin rod structures are found in diverse organisms, having been observed in spores of Dictyostelium discoideum, Drosophila melanogaster oocytes, as well as in numerous animal cells under stress conditions. GO:0031000 response to caffeine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0031000 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them. GO:0021670 lateral ventricle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021670 The process whose specific outcome is the progression of the lateral ventricles over time, from the formation to the mature structure. The two lateral ventricles are a cavity in each of the cerebral hemispheres derived from the cavity of the embryonic neural tube. They are separated from each other by the septum pellucidum, and each communicates with the third ventricle by the foramen of Monro, through which also the choroid plexuses of the lateral ventricles become continuous with that of the third ventricle. GO:0021671 rhombomere 7 morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021671 The process in which the anatomical structure of rhombomere 7 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. CHEBI:71224 flavan-3,3',4',5,5',7-hexol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71224 GO:0021672 rhombomere 7 structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021672 rhombomere 7 structural organisation The process that contributes to creating the structural organization of rhombomere 7. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. GO:0021673 rhombomere 7 formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021673 The process that gives rise to rhombomere 7. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. GO:0021674 rhombomere 8 morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021674 The process in which the anatomical structure of rhombomere 8 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. CHEBI:71227 (+)-epigallocatechin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71227 GO:0021675 nerve development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021675 The process whose specific outcome is the progression of a nerve over time, from its formation to the mature structure. GO:0021676 rhombomere 8 structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021676 rhombomere 8 structural organisation The process that contributes to creating the structural organization of rhombomere 8. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. GO:0006058 mannoprotein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006058 mannoprotein degradation|mannoprotein breakdown|mannoprotein catabolism The chemical reactions and pathways resulting in the breakdown of mannoproteins, any protein that contains covalently bound mannose residues. GO:0045622 regulation of T-helper cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045622 regulation of T-helper cell development Any process that modulates the frequency, rate or extent of T-helper cell differentiation. CHEBI:46280 beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GalpNAc biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_46280 GO:0045623 negative regulation of T-helper cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045623 negative regulation of T-helper cell development|down-regulation of T-helper cell differentiation|inhibition of T-helper cell differentiation|down regulation of T-helper cell differentiation|downregulation of T-helper cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper cell differentiation. GO:0006059 hexitol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006059 sugar alcohol (hexitol) metabolic process|hexitol metabolism|sugar alcohol (hexitol) metabolism The chemical reactions and pathways involving hexitols, any alditol with a chain of six carbon atoms in the molecule. GO:0045620 negative regulation of lymphocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045620 negative regulation of lymphocyte development|down-regulation of lymphocyte differentiation|downregulation of lymphocyte differentiation|down regulation of lymphocyte differentiation|inhibition of lymphocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte differentiation. GO:0006056 mannoprotein metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006056 mannoprotein metabolism The chemical reactions and pathways involving mannoproteins, any protein that contains covalently bound mannose residues. GO:0045621 positive regulation of lymphocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045621 positive regulation of lymphocyte development|up regulation of lymphocyte differentiation|upregulation of lymphocyte differentiation|stimulation of lymphocyte differentiation|up-regulation of lymphocyte differentiation|activation of lymphocyte differentiation Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation. GO:0006057 mannoprotein biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006057 mannoprotein biosynthesis|mannoprotein anabolism|mannoprotein synthesis|mannoprotein formation The chemical reactions and pathways resulting in the formation of mannoproteins, any protein that contains covalently bound mannose residues. GO:0006054 N-acetylneuraminate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006054 N-acetylneuraminate metabolism|sialic acid metabolism|sialic acid metabolic process The chemical reactions and pathways involving N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid. GO:0006055 CMP-N-acetylneuraminate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006055 CMP-N-acetylneuraminate formation|CMP-N-acetylneuraminate biosynthesis|CMP-N-acetylneuraminate anabolism|CMP-N-acetylneuraminate synthesis The chemical reactions and pathways resulting in the formation of CMP-N-acetylneuraminate, a substance composed of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid in glycosidic linkage with cytidine monophosphate. GO:0006052 N-acetylmannosamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006052 N-acetylmannosamine anabolism|N-acetylmannosamine synthesis|N-acetylmannosamine formation|N-acetylmannosamine biosynthesis The chemical reactions and pathways resulting in the formation of N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose. GO:0006053 N-acetylmannosamine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006053 N-acetylmannosamine degradation|N-acetylmannosamine breakdown|N-acetylmannosamine catabolism The chemical reactions and pathways resulting in the breakdown of N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose. GO:0006061 sorbitol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006061 sorbitol biosynthesis|sorbitol anabolism|sorbitol synthesis|sorbitol formation The chemical reactions and pathways resulting in the formation of sorbitol (D-glucitol), one of the ten stereoisomeric hexitols. It can be derived from glucose by reduction of the aldehyde group. GO:0006062 sorbitol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006062 MetaCyc:SORBDEG-PWY sorbitol catabolism|sorbitol degradation|sorbitol breakdown The chemical reactions and pathways resulting in the breakdown of sorbitol (D-glucitol), one of the ten stereoisomeric hexitols. It can be derived from glucose by reduction of the aldehyde group. GO:0045628 regulation of T-helper 2 cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045628 regulation of T-helper 2 cell development Any process that modulates the frequency, rate or extent of T-helper 2 cell differentiation. GO:0045629 negative regulation of T-helper 2 cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045629 down regulation of T-helper 2 cell differentiation|downregulation of T-helper 2 cell differentiation|negative regulation of T-helper 2 cell development|down-regulation of T-helper 2 cell differentiation|inhibition of T-helper 2 cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 2 cell differentiation. GO:0006060 sorbitol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0006060 MetaCyc:P461-PWY sorbitol metabolism The chemical reactions and pathways involving sorbitol (D-glucitol), one of the ten stereoisomeric hexitols. It can be derived from glucose by reduction of the aldehyde group. GO:0045626 negative regulation of T-helper 1 cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045626 down regulation of T-helper 1 cell differentiation|downregulation of T-helper 1 cell differentiation|negative regulation of T-helper 1 cell development|down-regulation of T-helper 1 cell differentiation|inhibition of T-helper 1 cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 1 cell differentiation. CHEBI:85856 CDP-1,2-dioleoyl-sn-glycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_85856 GO:0045627 positive regulation of T-helper 1 cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045627 upregulation of T-helper 1 cell differentiation|up regulation of T-helper 1 cell differentiation|positive regulation of T-helper 1 cell development|activation of T-helper 1 cell differentiation|stimulation of T-helper 1 cell differentiation|up-regulation of T-helper 1 cell differentiation Any process that activates or increases the frequency, rate or extent of T-helper 1 cell differentiation. GO:0045624 positive regulation of T-helper cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045624 stimulation of T-helper cell differentiation|up-regulation of T-helper cell differentiation|upregulation of T-helper cell differentiation|up regulation of T-helper cell differentiation|activation of T-helper cell differentiation|positive regulation of T-helper cell development Any process that activates or increases the frequency, rate or extent of T-helper cell differentiation. GO:0045625 regulation of T-helper 1 cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045625 regulation of T-helper 1 cell development Any process that modulates the frequency, rate or extent of T-helper 1 cell differentiation. GO:0021677 rhombomere 8 formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021677 The process that gives rise to rhombomere 8. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. GO:0021678 third ventricle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021678 The process whose specific outcome is the progression of the third ventricle over time, from its formation to the mature structure. The third ventricle is the narrow cleft inferior to the corpus callosum, within the diencephalon, between the paired thalami. Its floor is formed by the hypothalamus, its anterior wall by the lamina terminalis, and its roof by ependyma, and it communicates with the fourth ventricle by the cerebral aqueduct, and with the lateral ventricles by the interventricular foramina. GO:0021679 cerebellar molecular layer development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0021679 The process whose specific outcome is the progression of the cerebellar molecular layer nerve over time, from its formation to the mature structure. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells. CHEBI:71221 feruloylacetyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71221 CHEBI:224366 tert-butylammonium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_224366 CHEBI:12834 n-alkanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_12834 NCBITaxon:33634 Stramenopiles organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_33634 Heterokonta|Chromophyta|heterokonts|Straminipila NCBITaxon:33630 Alveolata organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_33630 alveolates NCBITaxon:33682 Euglenozoa organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_33682 Euglenozoans CHEBI:61817 1-palmitoyl-2-azelaoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61817 CHEBI:61820 beta-D-Gal-(1->3)-alpha-D-GalNAc biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_61820 CHEBI:61822 2-O-glutaroyl-1-O-palmitoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_61822 GO:0045592 regulation of cumulus cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045592 regulation of ovarian cumulus cell differentiation Any process that modulates the frequency, rate or extent of ovarian cumulus cell differentiation. GO:0045593 negative regulation of cumulus cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045593 downregulation of cumulus cell differentiation|down regulation of cumulus cell differentiation|inhibition of cumulus cell differentiation|negative regulation of ovarian cumulus cell differentiation|down-regulation of cumulus cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of ovarian cumulus cell differentiation. GO:0045590 negative regulation of regulatory T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045590 down regulation of regulatory T cell differentiation|negative regulation of regulatory T-cell differentiation|negative regulation of suppressor T-cell differentiation|downregulation of regulatory T cell differentiation|negative regulation of regulatory T-lymphocyte differentiation|negative regulation of regulatory T cell development|negative regulation of suppressor T cell differentiation|down-regulation of regulatory T cell differentiation|negative regulation of regulatory T lymphocyte differentiation|inhibition of regulatory T cell differentiation Any process that stops, prevents, or reduces the rate of differentiation of regulatory T cells. GO:0045591 positive regulation of regulatory T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045591 positive regulation of suppressor T-cell differentiation|positive regulation of regulatory T-cell differentiation|upregulation of regulatory T cell differentiation|positive regulation of regulatory T-lymphocyte differentiation|up regulation of regulatory T cell differentiation|positive regulation of regulatory T cell development|activation of regulatory T cell differentiation|positive regulation of suppressor T cell differentiation|stimulation of regulatory T cell differentiation|positive regulation of regulatory T lymphocyte differentiation|up-regulation of regulatory T cell differentiation Any process that activates or increases the frequency, rate or extent of differentiation of regulatory T cells. CHEBI:22221 acyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22221 GO:0045598 regulation of fat cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045598 regulation of adipocyte cell differentiation|regulation of adipocyte differentiation Any process that modulates the frequency, rate or extent of adipocyte differentiation. GO:0045599 negative regulation of fat cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045599 negative regulation of adipocyte differentiation|down-regulation of fat cell differentiation|downregulation of fat cell differentiation|down regulation of fat cell differentiation|inhibition of fat cell differentiation|negative regulation of adipocyte cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation. GO:0045596 negative regulation of cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045596 down-regulation of cell differentiation|downregulation of cell differentiation|down regulation of cell differentiation|inhibition of cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation. GO:0045597 positive regulation of cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045597 stimulation of cell differentiation|up-regulation of cell differentiation|activation of cell differentiation|up regulation of cell differentiation|upregulation of cell differentiation Any process that activates or increases the frequency, rate or extent of cell differentiation. GO:0045594 positive regulation of cumulus cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045594 up regulation of cumulus cell differentiation|upregulation of cumulus cell differentiation|stimulation of cumulus cell differentiation|up-regulation of cumulus cell differentiation|activation of cumulus cell differentiation|positive regulation of ovarian cumulus cell differentiation Any process that activates or increases the frequency, rate or extent of ovarian cumulus cell differentiation. GO:0045595 regulation of cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0045595 Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features. CHEBI:36863 22-hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36863 CHEBI:36864 25-hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36864 CHEBI:36861 14alpha-hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36861 CHEBI:71190 4-methoxy-4-oxo-3-phenylbutanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71190 GO:0070558 alphaM-beta2 integrin-CD63 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070558 ITGAM-ITGB2-CD63 complex A protein complex that consists of an alphaM-beta2 integrin complex bound to membrane protein CD63, a member of the tetraspan family. CHEBI:36865 24-hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36865 CHEBI:36866 23-hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36866 GO:0070559 lysosomal multienzyme complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070559 GALNS-lysosomal hydrolase 1.27 MDa complex A protein complex found in the lysosome that contains beta-galactosidase, cathepsin A, alpha-neuraminidase and N-acetylgalactosamine-6-sulfate sulfatase, and is involved in glycosaminoglycan catabolism. CHEBI:71191 3-oxocyclopentanecarboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71191 UBERON:0003458 neck bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003458 neck (volume) bone organ|bone of neck|bone organ of neck (volume)|bone organ of neck|neck (volume) bone|bone of neck (volume)|neck bone organ A bone that is part of a neck [Automatically generated definition]. CHEBI:71192 N-(cyanomethyl)glycinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71192 GO:0070556 TAF4B-containing transcription factor TFIID complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070556 TFIID complex, B-cell specific A transcription factor TFIID complex that contains the TBP-associated factor TAF4B (also known as TAFII105 in human), a cell-type-specific variant of TAF4. UBERON:0003459 chest bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003459 bone organ of anterolateral part of thorax|anterior thoracic region bone|anterolateral part of thorax bone organ|bone of anterior thoracic region|front of thorax bone|bone organ of chest|bone organ of front of thorax|anterior thoracic region bone organ|bone of anterolateral part of thorax|bone organ of anterior thoracic region|anterolateral part of thorax bone|front of thorax bone organ|chest bone organ|bone of chest|bone of front of thorax A bone that is part of a chest [Automatically generated definition]. GO:0070557 PCNA-p21 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070557 A protein complex that contains the cyclin-dependent protein kinase inhibitor p21WAF1/CIP1 bound to PCNA; formation of the complex inhibits DNA replication. UBERON:0003456 respiratory system lymphatic vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003456 lymph vessel of respiratory system|apparatus respiratorius lymph vessel|lymphatic vessel of apparatus respiratorius|lymphatic vessel of respiratory system|respiratory system lymph vessel|apparatus respiratorius lymphatic vessel|lymph vessel of apparatus respiratorius A lymphatic vessel that is part of a respiratory system [Automatically generated definition]. GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070554 Stx3-Snap25-Vamp2-Cplx1 complex|SNARE complex (Stx3, Snap25, Vamp2, Cplx1) A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 3, and a complexin (or orthologs thereof). UBERON:0003457 head bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003457 bone organ of adult head|bone organ of head|adult head bone|head bone organ|bone of adult head|craniofacial bone|adult head bone organ|bone of head A bone that is part of a head [Automatically generated definition]. GO:0070555 response to interleukin-1 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070555 response to IL-1 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus. CHEBI:22229 acylglutathione biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22229 UBERON:0003454 small intestine Peyer's patch biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003454 noduli lymphoidei aggregati intestini tenuis|Peyer's patch of small bowel|Peyer's patch of small intestine|small bowel Peyer's patch|Peyer's patch|aggregated lymphoid follicle of small intestine|small intestine Peyer's patch nodular lymphoid structures on the serosal surface of the small intestine. GO:0070552 BRISC complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070552 A protein complex that contains the FAM175B/ABRO1, BRCC3/BRCC36, BRE/BRCC45 and MERIT40/NBA1 proteins, and specifically cleaves K63-linked polyubiquitin chains. UBERON:0003455 inner renal medulla loop of Henle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003455 loop of Henle, inner medullary portion|kidney inner medulla loop of Henle A loop of Henle that is part of a inner medulla of kidney [Automatically generated definition]. GO:0070553 nicotinic acid receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070553 niacin receptor activity Combining with nicotinic acid to initiate a change in cell activity. CHEBI:36860 14-hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36860 UBERON:0003452 trabecula carnea cardiac muscle tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003452 trabecula carnea muscle of heart muscle tissue|textus muscularis of myocardium of trabecula carnea|cardiac muscle of trabecula carnea|trabecula carnea textus muscularis of cardiac muscle|cardiac muscle textus muscularis of trabecula carnea|trabecula carnea muscle tissue of muscle of heart|textus muscularis of heart muscle of trabecula carnea|muscle tissue of cardiac muscle of trabecula carnea|trabecula carnea myocardium textus muscularis|textus muscularis of heart myocardium of trabecula carnea|trabecula carnea heart muscle textus muscularis|trabecula carnea cardiac muscle muscle tissue|cardiac muscle tissue of trabecula carnea|muscle tissue of muscle of heart of trabecula carnea|myocardium textus muscularis of trabecula carnea|trabecula carnea textus muscularis of myocardium|trabecula carnea heart myocardium textus muscularis|muscle tissue of myocardium of trabecula carnea|muscle of heart textus muscularis of trabecula carnea|cardiac muscle muscle tissue of trabecula carnea|heart muscle textus muscularis of trabecula carnea|trabecula carnea muscle tissue of cardiac muscle|trabecula carnea textus muscularis of heart muscle|trabecula carnea textus muscularis of muscle of heart|muscle tissue of heart muscle of trabecula carnea|trabecula carnea textus muscularis of heart myocardium|heart myocardium textus muscularis of trabecula carnea|trabecula carnea myocardium muscle tissue|muscle tissue of heart myocardium of trabecula carnea|textus muscularis of muscle of heart of trabecula carnea|trabecula carnea heart muscle muscle tissue|myocardium muscle tissue of trabecula carnea|trabecula carnea muscle tissue of myocardium|trabecula carnea muscle of heart textus muscularis|trabecula carnea heart myocardium muscle tissue|muscle of heart muscle tissue of trabecula carnea|heart muscle muscle tissue of trabecula carnea|trabecula carnea muscle tissue of heart muscle|textus muscularis of cardiac muscle of trabecula carnea|heart myocardium muscle tissue of trabecula carnea|trabecula carnea muscle tissue of heart myocardium|trabecula carnea cardiac muscle|trabecula carnea cardiac muscle textus muscularis A portion of cardiac muscle tissue that is part of a trabecula carnea [Automatically generated definition]. CHEBI:71198 (2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71198 GO:0070550 rDNA condensation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070550 rDNA packaging The process in which the chromatin structure of the rDNA repeats is compacted. In S. cerevisiae, condensation and resolution of the rDNA occurs during anaphase. GO:0070551 endoribonuclease activity, cleaving siRNA-paired mRNA biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070551 argonaute endoribonuclease activity Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an siRNA, yielding 5'-phosphomonoesters. UBERON:0003453 large intestine Peyer's patch biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003453 solitary lymphoid follicle of subdivision of large intestine|large intestine Peyer's patch|Peyer's patch of large intestine|solitary lymphatic follicle of large intestine A Peyer's patch that is part of a large intestine. CHEBI:71199 hydroxymethylphosphonate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_71199 CHEBI:22231 acylglycerone phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22231 UBERON:0003438 iris nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003438 nerve of iris|ciliary nerve Any nerve that innervates the iris. CHEBI:22235 adamantanones biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22235 UBERON:0003439 nerve of trunk region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003439 nerve of trunk|nerve of torso|torso nerve|trunk nerve A nerve that is part of the trunk region of the body (not to be confused with a nerve trunk). CHEBI:36874 radical cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36874 UBERON:0003440 limb nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003440 nerve of limb A nerve that is part of a limb [Automatically generated definition]. CHEBI:36875 radical ion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36875 CHEBI:12886 (R)-4'-phosphopantothenate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_12886 CHEBI:36872 organic radical biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36872 NCBITaxon:9443 Primates organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_9443 primate|Primata|primates CHEBI:36873 radical anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36873 GO:0070549 negative regulation of translation involved in RNA interference biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070549 down-regulation of translation involved in RNA interference|RNA interference, negative regulation of translation|downregulation of translation involved in RNA interference|down regulation of translation involved in RNA interference|inhibition of translation involved in RNA interference A process of negative regulation of translation that is mediated by the association of small interfering RNAs (siRNAs) with a cognate target mRNA. CHEBI:36878 inorganic radical ion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36878 CHEBI:36879 inorganic radical cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36879 GO:0070547 L-tyrosine aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070547 Catalysis of the transfer of an amino group from L-tyrosine to an acceptor, usually a 2-oxo acid. CHEBI:36876 inorganic radical anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36876 GO:0070548 L-glutamine aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070548 Catalysis of the transfer of an amino group from L-glutamine to an acceptor, usually a 2-oxo acid. CHEBI:36877 organic radical anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36877 UBERON:0003447 digit nerve of manus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003447 nerve of finger|finger nerve|nerve of digit of hand|nerve of digitus manus|nerve of hand digit|digit of hand nerve|digitus manus nerve|nerve of digit of terminal segment of free upper limb|hand digit nerve|nerve of terminal segment of free upper limb digit|terminal segment of free upper limb digit nerve|digit of terminal segment of free upper limb nerve A nerve that is part of a finger [Automatically generated definition]. GO:0070545 PeBoW complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070545 A protein complex that is involved in coordinating ribosome biogenesis with cell cycle progression. In human, it is composed of Pes1, Bop1, and WDR12; in Saccharomyces the proteins are known as Nop7p, Erb1 and Ytm1 respectively. UBERON:0003448 manus nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003448 hand nerve|nerve of manus|nerve of hand A nerve that is part of a manus [Automatically generated definition]. GO:0070546 L-phenylalanine aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070546 Catalysis of the transfer of an amino group from L-phenylalanine to an acceptor, usually a 2-oxo acid. GO:0070543 response to linoleic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070543 response to linoleate Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a linoleic acid stimulus. UBERON:0003445 pes nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003445 foot nerve|nerve of foot A nerve that is part of a foot [Automatically generated definition]. UBERON:0003446 ankle nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003446 neural network of ankle|tarsal region nerve|nerve of ankle A nerve that is part of an ankle [Automatically generated definition]. GO:0070544 histone H3-K36 demethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070544 H3K36 demethylation The modification of histone H3 by the removal of a methyl group from lysine at position 36 of the histone. GO:0070541 response to platinum ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070541 response to platinum Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platinum stimulus. UBERON:0003443 thoracic cavity nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003443 cavity of thorax nerve|nerve of thoracic cavity|nerve of cavity of chest|nerve of pectoral cavity|cavity of chest nerve|pectoral cavity nerve|nerve of chest cavity|nerve of cavity of thorax|chest cavity nerve A nerve that is located in a thoracic cavity [Automatically generated definition]. GO:0070542 response to fatty acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070542 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus. UBERON:0003444 pelvis nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003444 nerve of pelvis A nerve that is part of a pelvis [Automatically generated definition]. CHEBI:36871 inorganic radical biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36871 UBERON:0003441 forelimb nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003441 wing nerve|nerve of superior member|nerve of upper extremity|nerve of fore limb|nerve of forelimb|fore limb nerve A nerve that is part of a forelimb [Automatically generated definition]. UBERON:0003442 hindlimb nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003442 nerve of hindlimb|nerve of inferior member|nerve of hind limb|hind limb nerve|nerve of lower extremity A nerve that is part of a hindlimb [Automatically generated definition]. GO:0070540 stearic acid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070540 Interacting selectively and non-covalently with stearic acid, the 18-carbon saturated fatty acid octadecanoic acid. GO:0070570 regulation of neuron projection regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070570 Any process that modulates the rate, frequency or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage. CHEBI:22200 acetylgentamycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22200 CHEBI:22201 acetylkanamycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22201 GO:0070571 negative regulation of neuron projection regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070571 growth cone collapse Any process that stops, prevents, or reduces the frequency, rate or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage. UBERON:0003429 abdomen nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003429 nerve of abdomen A nerve that is part of an abdomen [Automatically generated definition]. CHEBI:22204 acetylspermidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22204 CHEBI:22205 acetylspermine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22205 UBERON:0003427 abdominal fat pad biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003427 abdominal fat depot|abdomen fat pad|fat pad of abdomen The encapsulated adipose tissue in the abdomen. UBERON:0003428 gonadal fat pad biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003428 gonadal fat depot|gonadal fat pad|fat pad of gonads|gonad-associated fat pad|gonad fat pad|fat pad of gonad The encapsulated adipose tissue associated with the ovaries or testes. CHEBI:36849 6-hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36849 CHEBI:36847 12beta-hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36847 CHEBI:36848 5-hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36848 CHEBI:36841 11-hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36841 CHEBI:36842 19-hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36842 CHEBI:36840 16-hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36840 CHEBI:36845 12-hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36845 CHEBI:36846 12alpha-hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36846 CHEBI:36843 7alpha-hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36843 CHEBI:36844 7-hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36844 GO:0070578 RISC-loading complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070578 RLC|microRNA loading complex|miRLC A trimeric protein complex required for the formation of a mature RNA-induced silencing complex (RISC). In humans the complex is composed of the endonuclease Dicer (DICER1), TRBP (TARBP2) and the Argonaute protein Ago2 (EIF2C2/AGO2). Within the complex, Dicer and TRBP are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto Ago2. Ago2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from Dicer and TRBP. This complex has endoribonuclease activity. UBERON:0003436 shoulder nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003436 nerve of shoulder A nerve that is part of a shoulder [Automatically generated definition]. UBERON:0003437 eyelid nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003437 nerve of blepharon|blepharon nerve|nerve of eyelid|palpebral nerve A nerve that innervates an eyelid. GO:0070579 methylcytosine dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070579 Reactome:R-HSA-5221014|Reactome:R-HSA-5220952|Reactome:R-HSA-5220990 Catalysis of the reaction: methylcytosine + 2-oxoglutarate + O2 = 5-hydroxymethylcytosine + succinate + CO2. GO:0070576 vitamin D 24-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070576 ergocalciferol 24-hydroxylase activity|cholecalciferol 24-hydroxylase activity|vitamin D3 24-hydroxylase activity|calciferol 24-hydroxylase activity|vitamin D2 24-hydroxylase activity Catalysis of the hydroxylation of C-24 of any form of vitamin D. UBERON:0003434 wrist nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003434 nerve of wrist|nerve of carpal region|carpal region nerve A nerve that is part of a wrist [Automatically generated definition]. UBERON:0003435 pedal digit nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003435 nerve of foot digit|digit of foot nerve|digitus pedis nerve|foot digit nerve|nerve of digit of terminal segment of free lower limb|nerve of terminal segment of free lower limb digit|foot digit nerve|terminal segment of free lower limb digit nerve|digit of terminal segment of free lower limb nerve|nerve of toe|toe nerve|hind limb digit nerve|nerve of digitus pedis|nerve of digit of foot A nerve that is part of a toe [Automatically generated definition]. GO:0070577 lysine-acetylated histone binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070577 acetylated histone residue binding Interacting selectively and non-covalently with a histone in which a lysine residue has been modified by acetylation. GO:0070574 cadmium ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070574 transmembrane cadmium transport|cadmium ion membrane transport A process in which a cadmium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. UBERON:0003432 chest nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003432 nerve of chest|nerve of front of thorax|nerve of anterior thoracic region|front of thorax nerve|anterior thoracic region nerve|nerve of anterolateral part of thorax|anterolateral part of thorax nerve A nerve that is part of a chest [Automatically generated definition]. GO:0070575 peptide mating pheromone maturation involved in regulation of pheromone-induced unidirectional conjugation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070575 peptide mating pheromone processing involved in pheromone-induced unidirectional conjugation|peptide mating pheromone formation involved in pheromone-induced unidirectional conjugation The formation of a mature peptide mating pheromone by proteolysis and/or modification of a peptide precursor, occurring in the context of pheromone-induced unidirectional conjugation. UBERON:0003433 arm nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003433 nerve of arm|nerve of brachial region|brachial region nerve A nerve that is part of an arm [Automatically generated definition]. GO:0070572 positive regulation of neuron projection regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070572 Any process that activates or increases the frequency, rate or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage. UBERON:0003430 neck nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003430 nerve of neck (volume)|nerve of neck|neck (volume) nerve A nerve that is part of a neck [Automatically generated definition]. GO:0070573 metallodipeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070573 Reactome:R-HSA-2022405|Reactome:R-HSA-2022398|Reactome:R-HSA-2065355 metallo-exo-dipeptidase activity|metalloexodipeptidase activity Catalysis of the hydrolysis of a dipeptide by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. UBERON:0003431 leg nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003431 nerve of leg A nerve that is part of a leg [Automatically generated definition]. CHEBI:22211 aconitic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22211 GO:0070560 protein secretion by platelet biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070560 The regulated release of proteins by a platelet or group of platelets. CHEBI:22210 aconitate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_22210 UBERON:0003418 mesenchyme of submandibular gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003418 submaxillary gland mesenchyme|submandibular gland mesenchyme Mesenchyme that is part of a developing submandibular gland [Automatically generated definition]. CHEBI:22216 acrylamides biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22216 UBERON:0003416 mesenchyme of tongue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003416 tongue mesenchyme Mesenchyme that is part of a developing tongue [Automatically generated definition]. CHEBI:22213 acridines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_22213 UBERON:0003417 mesenchyme of soft palate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003417 soft palate mesenchyme Mesenchyme that is part of a developing soft palate [Automatically generated definition]. CHEBI:36859 2beta-hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36859 CHEBI:36852 26-hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36852 CHEBI:36853 hydroxy seco-steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36853 CHEBI:36850 6alpha-hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36850 CHEBI:36851 6beta-hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36851 CHEBI:36856 hydrogen isocyanide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36856 CHEBI:36857 2-hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36857 GO:0070569 uridylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070569 uridyl transferase activity|uridyltransferase activity Catalysis of the transfer of an uridylyl group to an acceptor. CHEBI:36854 20-hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36854 CHEBI:36855 18-hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36855 GO:0070567 cytidylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070567 Catalysis of the transfer of a cytidylyl group to an acceptor. UBERON:0003425 renal lymph node biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003425 lymph node of kidney|kidney lymph node A lymph node that is located in a kidney [Automatically generated definition]. UBERON:0003426 dermis adipose tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003426 dermis fatty tissue|adipose tissue of dermis|fat tissue of dermis|fatty tissue of dermis|dermis fat tissue An adipose tissue that is part of a dermis [Automatically generated definition]. GO:0070568 guanylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070568 Catalysis of the transfer of a guanylyl group to an acceptor. GO:0070565 telomere-telomerase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0070565 A complex of DNA and protein located at the end of a linear chromosome that enables replication of the telomeric repeat sequences at the end of a linear chromosome. GO:0070566 adenylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070566 Catalysis of the transfer of an adenylyl group to an acceptor. UBERON:0003424 mesenchyme of hard palate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003424 hard palate mesenchyme Mesenchyme that is part of a developing hard palate [Automatically generated definition]. GO:0070563 negative regulation of vitamin D receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070563 negative regulation of VDR signaling pathway|down-regulation of vitamin D receptor signaling pathway|negative regulation of VDR signalling pathway|downregulation of vitamin D receptor signaling pathway|down regulation of vitamin D receptor signaling pathway|inhibition of vitamin D receptor signaling pathway|negative regulation vitamin D receptor signalling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the vitamin D receptor signaling pathway activity. GO:0070564 positive regulation of vitamin D receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070564 up-regulation of vitamin D receptor signaling pathway|activation of vitamin D receptor signaling pathway|positive regulation of VDR signaling pathway|positive regulation of vitamin D receptor signalling pathway|up regulation of vitamin D receptor signaling pathway|upregulation of vitamin D receptor signaling pathway|stimulation of vitamin D receptor signaling pathway Any process that activates or increases the frequency, rate or extent of vitamin D receptor signaling pathway activity. UBERON:0003422 mesenchyme of umbilical cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003422 umbilical cord mesenchyme|Wharton's jelly A gelatinous substance within the umbilical cord, largely made up of mucopolysaccharides (hyaluronic acid and chondroitin sulfate). It also contains some fibroblasts and macrophages. It is derived from Extra Embryonic Mesoderm[WP] GO:0070561 vitamin D receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070561 vitamin D receptor signalling pathway|VDR signaling pathway|calcitriol signaling pathway The series of molecular signals generated as a consequence of a vitamin D receptor binding to one of its physiological ligands. GO:0070562 regulation of vitamin D receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070562 regulation of vitamin D receptor signalling pathway|regulation of VDR signaling pathway Any process that modulates the frequency, rate or extent of vitamin D receptor signaling pathway activity. GO:0070592 cell wall polysaccharide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070592 cell wall polysaccharide synthesis|cell wall polysaccharide biosynthesis|cell wall polysaccharide anabolism The chemical reactions and pathways resulting in the formation of a polysaccharide destined to form part of a cell wall. GO:0070593 dendrite self-avoidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070593 dendrite repulsion The process in which dendrites recognize and avoid contact with sister dendrites from the same cell. GO:0070590 spore wall biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070590 A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a spore wall. A spore wall is the specialized cell wall lying outside the cell membrane of a spore. GO:0070591 ascospore wall biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070591 A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of an ascospore wall. CHEBI:36828 pseudohalide anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36828 CHEBI:36829 polyatomic monoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36829 UBERON:0003494 respiratory system venule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003494 venule of apparatus respiratorius|venule of respiratory system|apparatus respiratorius venule A venule that is part of a respiratory system [Automatically generated definition]. UBERON:0003495 respiratory system arteriole biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003495 An arteriole that is part of a respiratory system [Automatically generated definition]. CHEBI:36820 ring assembly biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36820 CHEBI:36823 pseudohalo group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36823 GO:0070598 cell wall (1->3)-alpha-glucan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070598 cell wall 1,3-alpha-glucan anabolism|cell wall alpha-1,3-glucan anabolism|cell wall alpha-1,3-glucan biosynthetic process|cell wall 1,3-alpha-glucan biosynthesis|cell wall 1,3-alpha-glucan biosynthetic process|cell wall 1,3-alpha-glucan synthesis|cell wall alpha-1,3-glucan synthesis|cell wall alpha-1,3-glucan biosynthesis|cell wall 1,3-alpha-glucan formation|cell wall alpha-1,3-glucan formation The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-glucosidic bonds, found in the walls of cells. GO:0070599 fungal-type cell wall (1->3)-alpha-glucan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070599 ascospore wall alpha-1,3 glucan metabolic process|ascospore wall alpha-1,3 glucan metabolism|ascospore wall 1,3-alpha-glucan metabolism|ascospore wall 1,3-alpha-glucan metabolic process The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of ascospores. GO:0070596 (1->3)-alpha-glucan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070596 1,3-alpha-glucan synthesis|alpha-1,3 glucan biosynthesis|1,3-alpha-glucan formation|alpha-1,3 glucan biosynthetic process|alpha-1,3 glucan anabolism|alpha-1,3 glucan synthesis|1,3-alpha-glucan biosynthetic process|alpha-1,3 glucan formation|1,3-alpha-glucan biosynthesis|1,3-alpha-glucan anabolism The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds. UBERON:0003498 heart blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003498 blood vessel of heart|cardiac blood vessel A blood vessel that is part of a heart [Automatically generated definition]. GO:0070597 cell wall (1->3)-alpha-glucan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070597 cell wall alpha-1,3 glucan metabolism|cell wall alpha-1,3 glucan metabolic process|cell wall 1,3-alpha-glucan metabolism|cell wall 1,3-alpha-glucan metabolic process The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells. UBERON:0003499 brain blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003499 blood vessel of brain A blood vessel that is part of a brain [Automatically generated definition]. GO:0070594 juvenile hormone response element binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0070594 JHRE binding Interacting selectively and non-covalently with the juvenile hormone response element (JHRE), a conserved sequence found in the promoters of genes whose expression is regulated in response to juvenile hormone. UBERON:0003496 head blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003496 adult head blood vessel|blood vessel of adult head|blood vessel of head A blood vessel that is part of a head [Automatically generated definition]. GO:0070595 (1->3)-alpha-glucan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070595 alpha-1,3 glucan metabolic process|alpha-1,3 glucan metabolism|1,3-alpha-glucan metabolic process|1,3-alpha-glucan metabolism The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds. UBERON:0003497 abdomen blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003497 blood vessel of abdomen A blood vessel that is part of an abdomen [Automatically generated definition]. GO:0070581 rolling circle DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070581 rolling circle replication A DNA-dependent DNA replication process in which a single-stranded DNA molecule is synthesized from a circular duplex template. Replication typically does not cease when one circumference has been replicated, but continues around the circumference several more times, producing a long single strand comprising multimers of the replicon. GO:0070582 theta DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070582 theta replication A DNA-dependent DNA replication process in which a double-stranded DNA molecule is synthesized from a circular duplex template. GO:0070580 base J metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070580 beta-D-glucosyl-hydroxymethyluracil metabolism|beta-D-glucosyl-HOMedU metabolic process|base J metabolism The chemical reactions and pathways involving base J (beta-D-glucosyl-hydroxymethyluracil), a hypermodified thymidine residue found in the genome of kinetoplastid parasites. This modified base is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation. The base is synthesized in a two-step pathway. Initially, a thymidine residue in DNA is hydroxylated by a thymidine hydroxylase (TH) to form the intermediate hydroxymethyluracil, which is then glucosylated to form base J. CHEBI:36838 17-hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36838 CHEBI:36836 3beta-hydroxy steroid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36836 UBERON:0003483 thymus lymphoid tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003483 lymphoid tissue of thymus gland|thymus gland lymphoid tissue|lymphoid tissue of thymus A portion of lymphoid tissue that is part of a thymus [Automatically generated definition]. CHEBI:36830 monoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36830 UBERON:0003484 eye sebaceous gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003484 sebaceous gland of vertebrate eye|vertebrate eye sebaceous gland|camera-type eye sebaceous gland|sebaceous gland of camera-type eye A sebaceous gland that is part of a camera-type eye. Example: a tarsal gland. UBERON:0003481 tail vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003481 vein of post-vent region|vein of tail|post-vent region vein|caudal vein A vein that is part of a tail [Automatically generated definition]. UBERON:0003482 vein of trabecular bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003482 trabecular bone tissue vein|vein of trabecular bone tissue|spongy bone vein|vein of spongy bone|trabecular bone vein A portion of vein that is part of a trabecular bone tissue [Automatically generated definition]. CHEBI:36834 3-hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36834 UBERON:0003480 vein of clitoris biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003480 clitoris vein A vein that is part of a clitoris [Automatically generated definition]. CHEBI:36835 3alpha-hydroxy steroid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36835 GO:0070589 cellular component macromolecule biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070589 cellular component macromolecule biosynthesis The chemical reactions and pathways resulting in the formation of a macromolecule that is destined to form part of a specific cellular component. UBERON:0003489 respiratory system capillary endothelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003489 apparatus respiratorius endothelium of blood capillary|blood capillary endothelium of apparatus respiratorius|endothelium of capillary vessel of apparatus respiratorius|respiratory system capillary vessel endothelium|capillary endothelium of respiratory system|respiratory system endothelium of capillary|capillary endothelium of apparatus respiratorius|endothelium of capillary vessel of respiratory system|blood capillary endothelium of respiratory system|respiratory system endothelium of blood capillary|respiratory system endothelium of capillary vessel|capillary vessel endothelium of respiratory system|endothelium of capillary of respiratory system|endothelium of blood capillary of apparatus respiratorius|respiratory system blood capillary endothelium|endothelium of blood capillary of respiratory system|apparatus respiratorius capillary endothelium|endothelium of capillary of apparatus respiratorius|apparatus respiratorius capillary vessel endothelium|capillary vessel endothelium of apparatus respiratorius|apparatus respiratorius endothelium of capillary|apparatus respiratorius endothelium of capillary vessel|apparatus respiratorius blood capillary endothelium An endothelium of capillary that is part of a respiratory system [Automatically generated definition]. GO:0070587 regulation of cell-cell adhesion involved in gastrulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070587 Any process that modulates the frequency, rate, or extent of attachment of a cell to another cell affecting gastrulation. GO:0070588 calcium ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070588 calcium ion membrane transport|transmembrane calcium transport A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. UBERON:0003487 skin sebaceous gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003487 sebaceous gland of skin|cutaneous sebaceous gland A holocrine gland of the dermis that secretes sebum into hair follicles. GO:0070585 protein localization to mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070585 protein localisation in mitochondrion|protein localization in mitochondrion A process in which a protein is transported to, or maintained in, a location within the mitochondrion. UBERON:0003488 abdominal mammary gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003488 abdomen lobe of breast|lactiferous gland of abdomen|abdomen mammary gland|lobe of mammary gland of abdomen|lobe of breast of abdomen|abdomen lobe of mammary gland|mammary gland of abdomen|abdomen lactiferous gland A lactiferous gland that is part of the abdominal region [Automatically generated definition]. GO:0070586 cell-cell adhesion involved in gastrulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070586 The attachment of one cell to another cell affecting gastrulation. UBERON:0003485 vagina sebaceous gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003485 sebaceous gland of vagina A sebaceous gland that is part of a vagina [Automatically generated definition]. GO:0070583 spore membrane bending pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070583 FSM bending|ascospore-type prospore membrane bending|forespore membrane bending The process in which a bending force is generated in the prospore membrane to form the characteristic curved shape of the prospore. GO:0070584 mitochondrion morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0070584 The process in which the anatomical structures of a mitochondrion are generated and organized. CHEBI:36807 hydrochloride biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36807 UBERON:0003472 cerebellar artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003472 An artery that supplies blood to the cerebellum. UBERON:0003473 thoracic cavity artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003473 thoracic artery An artery that is part of a thoracic cavity[cjm]. CHEBI:12875 trans-2-coumarate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_12875 UBERON:0003470 artery of upper lip biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003470 ramus labialis superior arteriae facialis|superior labial artery|arteria labialis superior|superior labial branch of facial artery The superior labial artery (superior labial branch of facial artery) is larger and more tortuous than the inferior labial artery. It follows a similar course along the edge of the upper lip, lying between the mucous membrane and the Orbicularis oris, and anastomoses with the artery of the opposite side. It supplies the upper lip, and gives off in its course two or three vessels which ascend to the nose; a septal branch ramifies on the nasal septum as far as the point of the nose, and an alar branch supplies the ala of the nose. CHEBI:12876 trans-4-coumarate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_12876 UBERON:0003471 artery of lower lip biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003471 ramus labialis inferior arteriae facialis|inferior labial artery|inferior labial branch of facial artery|arteria labialis inferior|ramus labialis inferior (arteria facialis) The Iinferior labial artery (inferior labial branch of facial artery) arises near the angle of the mouth; it passes upward and forward beneath the Triangularis and, penetrating the Orbicularis oris, runs in a tortuous course along the edge of the lower lip between this muscle and the mucous membrane. It supplies the labial glands, the mucous membrane, and the muscles of the lower lip; and anastomoses with the artery of the opposite side, and with the mental branch of the inferior alveolar artery. UBERON:0003478 vein of lower lip biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003478 lower lip vein|venae labiales inferiores|vena labialis inferior|inferior labial vein The inferior labial vein is the vein receiving blood from the lower lip. UBERON:0003479 thoracic cavity vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003479 cavity of thorax vein|vein of thoracic cavity|vein of cavity of chest|vein of pectoral cavity|chest cavity vein|pectoral cavity vein|vein of chest cavity|cavity of chest vein|vein of cavity of thorax A vein that is part of a thoracic cavity [Automatically generated definition]. UBERON:0003476 respiratory system venous blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003476 vein of respiratory system|vein of apparatus respiratorius|apparatus respiratorius vein|respiratory system vein A vein that is part of a respiratory system [Automatically generated definition]. UBERON:0003477 vein of upper lip biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003477 vena labialis superior|upper lip vein|superior labial vein The inferior labial vein is the vein receiving blood from the upper lip. UBERON:0003474 meningeal artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003474 One of the arteries supplying a meninix[Automatically generated definition]. UBERON:0003475 ureteric vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003475 ureter vein|vein of ureter A vein that is part of a ureter [Automatically generated definition]. CHEBI:36816 oxime O-ether biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36816 CHEBI:36818 seco-cholestane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36818 CHEBI:36819 seco-ergostane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_36819 UBERON:0003461 shoulder bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003461 bone of shoulder|shoulder-articulating bone A bone that is connected via a shoulder joint (i.e. glenohumeral or acromioclavicular joints). The shoulder bones are the clavicle, scapula and humerus - but note that these are only considered to be shoulder bones when a true shoulder is present, as in most tetrapods. UBERON:0003462 facial bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003462 facial bone|bone of facial skeleton|bone of viscerocranium|facial skeleton bone|viscerocranium bone A bone that is part of a facial skeleton [Automatically generated definition]. UBERON:0003460 arm bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003460 bone of arm|bone of upper extremity|bone organ of arm|arm bone organ A bone that is part of the region of the forelimb that includes the zeugopod and stylopod. Examples: patella, femur, tibia CHEBI:36810 (trifluoromethyl)benzene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_36810 UBERON:0003469 respiratory system artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003469 An artery that is part of a respiratory system [Automatically generated definition]. UBERON:0003468 ureteric segment of renal artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003468 ureteric artery The ureteral branches of renal artery are small branches which supply the ureter. UBERON:0003466 forelimb zeugopod bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003466 zeugopod bone, forelimb|arm zeugopod bone|antebrachial region bone|lower arm bone|wing zeugopod bone|arm zeugopod bone organ|zeugopod bone, upper|antebrachial region bone organ A bone that is part of a lower arm [Automatically generated definition]. UBERON:0003463 trunk bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003463 bone organ of trunk|bone organ of torso|torso bone|bone of trunk|bone of torso|torso bone organ|trunk bone organ A bone that is part of a trunk [Automatically generated definition]. UBERON:0003464 hindlimb bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0003464 bone organ of lower extremity|bone of hindlimb|bone of inferior member|bone of hind limb|hindlimb bone organ|hind limb bone|bone of lower extremity|bone organ of hindlimb|bone organ of hind limb|hind limb bone organ A bone that is part of a hindlimb region. Examples: any pes phalanx, femur. Counter-examples: ischium, pubis (they are part of the pelvic girdle) CHEBI:76801 narbomycin(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76801 GO:1990630 IRE1-RACK1-PP2A complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990630 IRE1alpha-RACK1-PP2A complex|ERN1-RACK1-PP2A complex A protein complex consisting of IRE1 (Inositol-requiring enzyme-1), RACK1 (Receptor of activated protein kinase C 1, GNB2L1) and PP2A (protein phosphatase 2A). RACK1 acts as an adaptor to bridge an interaction between IRE1 and PP2A. CHEBI:27879 6-methylpretetramide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27879 CHEBI:76802 5-O-beta-D-mycaminosyltylactone(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76802 GO:1990631 ErbB-4 class receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990631 HER4 receptor binding Interacting selectively and non-covalently with the protein-tyrosine kinase receptor ErbB-4/HER4. GO:1990632 branching involved in submandibular gland morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990632 submandibular gland branching morphogenesis|submandibular gland ductal branching The process in which the branching structure of the submandibular gland is generated and organized. CHEBI:52837 quinolinium ion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52837 CHEBI:76800 pikromycin(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76800 UBERON:0010260 umbilical blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010260 allantoic vessel|umbilical cord blood vessel|umbilical vasculature|umbilical vessel|umbilical cord blood vessels One of the three blood vessels, usually one large umbilical vein and two small umbilical arteries, buried within Wharton's jelly, that transport blood to and from the placenta, where exchange between the mother and fetus takes place; the umbilical vein carries oxygenated, nutrient-rich blood from the placenta to the fetus, and the umbilical arteries carry deoxygenated, nutrient-depleted blood from the fetus to the placenta. CHEBI:52831 Delta(11)-fatty acyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52831 CHEBI:76803 5-O-beta-D-mycaminosyl-20-oxotylonolide(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76803 CHEBI:27877 N-acetyl-D-glucosaminyl-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27877 CHEBI:76804 5-O-mycaminosyltylonolide(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76804 CHEBI:76809 EC 3.5.4.* (non-peptide cyclic amidine C-N hydrolase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76809 CHEBI:27871 chloroacetaldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27871 CHEBI:76807 EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76807 CHEBI:76808 EC 3.5.2.* (non-peptide cyclic amide C-N hydrolase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76808 CHEBI:52839 acridinium ion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52839 UBERON:0010258 mesenchyme from rhombencephalic neural crest biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010258 Mesenchyme that develops_from a rhombencephalon neural crest. UBERON:0010259 1st arch mesenchyme from neural crest biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010259 mesenchyme derived from neural crest of mesenchyme of 1st arch|branchial arch 1 mesenchyme from neural crest|pharyngeal arch 1 mesenchyme from neural crest|neural crest derived arch 1 mesenchyme Mesenchyme that develops_from a neural crest and is part of a 1st arch mesenchyme. GO:1990637 response to prolactin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990637 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prolactin stimulus. The anterior pituitary hormone prolactin has a number of roles including being essential for lactation. GO:1990638 response to granulocyte colony-stimulating factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990638 response to G-CSF Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte colony-stimulating factor stimulus. GO:1990639 obsolete inositol-3,4,5-trisphosphate 5-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990639 inositol-3,4,5-trisphosphate 5-phosphatase activity OBSOLETE. Catalysis of the reaction: D-myo-inositol 3,4,5-trisphosphate + H2O = myo-inositol 3,4-bisphosphate + phosphate. GO:1990633 mutator focus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990633 A type of punctate focus localized to the perinuclear region of germline cytoplasm in C. elegans. Mutator foci are required for RNA interference (RNAi) and serve as sites of small inhibitory RNA (siRNA) amplification. As such, proteins that localize to mutator foci include RNA-directed RNA polymerases (RdRPs) and beta-nucleotidyltransferases. Mutator foci are distinct from, but adjacent to or partially overlap, P granules. GO:1990634 protein phosphatase 5 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990634 protein phosphatase T binding Interacting selectively and non-covalently with the enzyme protein phosphatase 5. GO:1990635 proximal dendrite biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990635 The dendrite of the dendritic tree that is closest to the neuronal cell body (the soma). GO:1990636 reproductive senescence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990636 A natural reduction in reproductive capacity with aging, often taking the form of a switch from regular reproductive cycles to irregular and infrequent ones. CHEBI:76812 EC 2.7.11.* (protein-serine/threonine kinase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76812 GO:1990640 inositol-2,4,5-triphosphate 5-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990640 Catalysis of the reaction: 1D-myo-inositol 2,4,5-trisphosphate + H2O = 1D-myo-inositol 2,4-bisphosphate + phosphate. GO:1990641 response to iron ion starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990641 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of iron ion. GO:1990642 obsolete response to castration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990642 response to castration OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a castration stimulus, deprivation of gonads. CHEBI:76810 demethyllactenocin(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76810 GO:1990643 cellular response to granulocyte colony-stimulating factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990643 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte colony-stimulating factor stimulus. CHEBI:76811 EC 3.1.4.12 (sphingomyelin phosphodiesterase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76811 CHEBI:76816 EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76816 CHEBI:76817 EC 2.7.10.* (protein-tyrosine kinase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76817 CHEBI:76814 dTDP-beta-L-mycarose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76814 CHEBI:27887 6-phospho-beta-D-galactoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27887 CHEBI:27888 chlorophyll b biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27888 CHEBI:76815 EC 2.7.7.* (nucleotidyltransferase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76815 UBERON:0010252 1st arch mandibular mesenchyme from neural crest biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010252 Mesenchyme that develops_from a neural crest and is part of a 1st arch mandibular mesenchyme. CHEBI:27881 resveratrol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27881 UBERON:0010253 1st arch maxillary mesenchyme from neural crest biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010253 Mesenchyme that develops_from a neural crest and is part of a 1st arch maxillary mesenchyme. CHEBI:76819 demethylmacrocin(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76819 CHEBI:27884 D-fructofuranose 2-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27884 UBERON:0010256 4th arch mesenchyme from neural crest biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010256 4th pharyngeal arch mesenchyme derived from neural crest|mesenchyme derived from neural crest of mesenchyme of 4th arch|branchial arch 4 mesenchyme from neural crest|pharyngeal arch 4 mesenchyme from neural crest|neural crest derived arch 4 mesenchyme Mesenchyme that develops_from a neural crest and is part of a 4th arch mesenchyme. UBERON:0010257 6th arch mesenchyme from neural crest biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010257 neural crest derived arch 6 mesenchyme|pharyngeal arch 6 mesenchyme from neural crest|branchial arch 6 mesenchyme from neural crest Mesenchyme that develops_from a neural crest and is part of a 6th arch mesenchyme. UBERON:0010254 2nd arch mesenchyme from neural crest biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010254 branchial arch 2 mesenchyme from neural crest|pharyngeal arch 2 mesenchyme from neural crest|neural crest derived arch 2 mesenchyme Mesenchyme that develops_from a neural crest and is part of a 2nd arch mesenchyme. UBERON:0010255 3rd arch mesenchyme from neural crest biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010255 3rd pharyngeal arch mesenchyme derived from neural crest|mesenchyme derived from neural crest of mesenchyme of 3rd arch|branchial arch 3 mesenchyme from neural crest|pharyngeal arch 3 mesenchyme from neural crest|neural crest derived arch 3 mesenchyme Mesenchyme that develops_from a neural crest and is part of a 3rd arch mesenchyme. CHEBI:37205 pentol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37205 CHEBI:37208 pinitol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37208 CHEBI:37209 L-pinitol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37209 CHEBI:37206 hexol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37206 CHEBI:37207 cis-3-dodecenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37207 GO:1990648 inositol-4,5,6-triphosphate 5-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990648 Catalysis of the reaction: 1D-myo-inositol 4,5,6-trisphosphate + H2O = 1D-myo-inositol 4,6-bisphosphate + phosphate. GO:1990649 inositol-1,2,4,5-tetrakisphosphate 5-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990649 Catalysis of the reaction: 1D-myo-inositol 1,2,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,2,4-trisphosphate + phosphate. GO:1990644 microtubule site clamp biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990644 The binding activity of a molecule that attaches the spindle microtubules to the kinetochore. GO:1990645 obsolete phosphorylase dephosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990645 phosphorylase dephosphorylation OBSOLETE. The modification of phosphorylases by removal of phosphate groups. GO:1990646 cellular response to prolactin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990646 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prolactin stimulus. GO:1990647 C/EBP complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990647 IntAct:EBI-10637780 C/EBPbeta homodimer complex|C/EBPalpha homodimer complex|C/EBPalpha complex|C/EBPbeta complex|C/EBP transcription factor complex|C/EBP homodimer complex A dimeric, sequence specific DNA-binding transcription factor complex regulating the expression of genes involved in immune and inflammatory responses. Exists at least as alpha and beta homodimeric forms. Binds to regulatory regions of several acute-phase and cytokines genes and probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Transcription factor activity is inhibited by binding of CHOP forming heterodimers with alternative transcription factor activities. GO:1990651 inositol-1,2,4,5,6-pentakisphosphate 5-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990651 Catalysis of the reaction: 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,4,6-tetrakisphosphate + phosphate. CHEBI:27856 acetamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27856 CHEBI:76823 EC 6.3.1.* (acid-ammonia/amine ligase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76823 CHEBI:76824 EC 6.4.1.* (carboxylase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76824 GO:1990652 obsolete positive regulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990652 positive regulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of pyrimidine-containing compound salvage. CHEBI:27857 (1->4)-beta-D-mannan biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27857 GO:1990653 obsolete monounsaturated fatty acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990653 OBSOLETE. The chemical reactions and pathways resulting in the formation of a monounsaturated fatty acid. A monounsaturated fatty acid has one double bond in the fatty acid chain with all of the remainder carbon atoms being single-bonded, as opposed to polyunsaturated fatty acids. CHEBI:76821 beta-D-Manp-(1->4)-D-GlcpNAc biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76821 CHEBI:27858 precorrin-6Y biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27858 CHEBI:27859 S-methyl-5-thio-alpha-D-ribose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27859 GO:1990654 sebum secreting cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990654 sebocyte proliferation The multiplication or reproduction of sebocytes by cell division, resulting in the expansion of their population. A sebocyte is an epithelial cell that makes up the sebaceous glands, and secrete sebum. CHEBI:27852 3,4-dihydroxymandelaldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27852 CHEBI:76825 cellobionate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76825 GO:1990650 inositol-2,4,5,6-tetrakisphosphate 5-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990650 Catalysis of the reaction: 1D-myo-inositol 2,4,5,6-tetrakisphosphate + H2O = 1D-myo-inositol 2,4,6-trisphosphate + phosphate. CHEBI:27855 L-erythro-3-methylmalyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27855 CHEBI:76829 EC 5.4.3.* (intramolecular transferase transferring amino groups) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76829 CHEBI:27851 keto-neuraminic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27851 UBERON:0010243 merocrine gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010243 An exocrine gland whose secretions are excreted via exocytosis from secretory cells into an epithelial-walled duct or ducts and thence onto a bodily surface or into the lumen; the gland releases its product and no part of the gland is lost or damaged. CHEBI:13248 anilide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_13248 GO:1990659 sequestering of manganese ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990659 sequestration of manganese ion|manganese ion retention|storage of manganese ion|manganese ion sequestering|manganese ion storage|retention of manganese ion|manganese ion sequestration The process of binding or confining manganese ions such that they are separated from other components of a biological system. GO:1990655 4 iron, 3 sulfur cluster binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990655 4Fe-3S cluster binding Interacting selectively and non-covalently with a 4 iron, 3 sulfur (4Fe-3S) cluster, an uncommon iron-sulfur cluster with unique properties found in oxygen-tolerant Ni-Fe hydrogenases of various bacteria. GO:1990656 t-SNARE clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990656 The clustering process in which t-SNARES are localized to distinct domains in the cell membrane. t-SNAREs are cell surface proteins which are part of secretory microdomain assemblies. CHEBI:76820 macrocin(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76820 GO:1990657 iNOS-S100A8/A9 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990657 IntAct:EBI-10105915|IntAct:EBI-10106087 A protein complex capable of stimulus-inducible nitric-oxide synthase activity. S-nitrosylates cysteine residues in target proteins, a principal mechanism of nitric oxide (NO)-mediated signal transduction. In mammals consists of NOS2, S100A8 and S100A9. S100A9 acts both as an adaptor linking NOS2 to its target and as a transnitrosylase that transfers the nitric oxide moiety from NOS2 to its target, via its own S-nitrosylated cysteine. GO:1990658 transnitrosylase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990658 transferase complex, transferring nitrogenous groups A transferase complex which is capable of transferring nitrogenous groups from one component to another. CHEBI:27867 antheraxanthin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27867 GO:1990662 S100A9 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990662 IntAct:EBI-10099500|IntAct:EBI-10099571 S100A9 homodimer A protein complex composed of a S100A9 dimer and capable of binding to toll-like receptor 4 (TLR4) and the receptor for advanced glycation end products (RAGE) initiating signal transduction through NF-kappa-B pathways. Transports arachidonic acid between the cytosol and the NADPH oxidase complex at the plasma membrane in neutrophils as part of an inflammatory signal cascade leading to an oxidative burst. Complexes with microtubules to increase cell motility. CHEBI:76834 EC 2.5.* (non-methyl-alkyl or aryl transferase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76834 GO:1990663 dihydroorotate dehydrogenase (fumarate) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990663 EC:1.3.98.1 Catalysis of the reaction: (S)-dihydroorotate + fumarate = orotate + succinate. CHEBI:76835 EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76835 CHEBI:27868 3-oxolauroyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27868 GO:1990664 Nkx-2.5 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990664 IntAct:EBI-10636829 NKX2.5 complex|Nkx-2.5 homodimer complex|NKX2E homodimer complex|NKX.2-5 homodimer complex A transcription factor complex formed by two or more subunits of Nkx-2.5. Nkx-2.5 is an evolutionary conserved transcription factor important for the specification and differentiation of cardiomyocytes during heart development. It is also required for spleen development. It binds DNA either as a monomer, or a homodimer, or a heterodimer complex to activate or inhibit expression of genes. CHEBI:76832 EC 4.3.1.* (ammonia-lyase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76832 CHEBI:27869 chloroacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27869 GO:1990665 AnxA2-p11 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990665 Annexin A2 tetramer|(p11)2.(AnxA2)2 complex|(A2.p11)2 complex|AnxA2:S100A10 heterotetramer|Annexin A2-p11 complex|AnxA2.p11 complex A heterotetrameric protein complex comprising two Annexin A2 (AnxA2) monomers and two copies of its binding partner, S100 protein p11 (S100A10). CHEBI:76838 EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76838 CHEBI:76839 dTDP-beta-L-vancosamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76839 GO:1990660 calprotectin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990660 IntAct:EBI-10098713|IntAct:EBI-10098135|IntAct:EBI-10098681 calprotectin heterodimer A protein complex composed of S100A8 and S100A9 and capable of limiting Mn(2+) and Zn(2+) availability at sites of infection. Also binds Ca(2+). Expressed and released by neutrophils and epithelial cells, it exhibits broad-spectrum antimicrobial activity attributed to its metal-binding properties. Endogenous ligand of toll-like receptor 4 (TLR4) and of the receptor for advanced glycation end products (RAGE) initiating signal transduction through NF-kappa-B pathways. CHEBI:27865 fucosterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27865 CHEBI:76836 EC 1.1.3.* (oxidoreductase acting on donor CH-OH group, oxygen as acceptor) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76836 GO:1990661 S100A8 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990661 IntAct:EBI-10098921|IntAct:EBI-10099454 S100A8 homodimer A protein complex composed of a S100A8 dimer and capable of binding to toll-like receptor 4 (TLR4). CHEBI:76837 EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76837 UBERON:0010230 eyeball of camera-type eye biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010230 eyeball|eye|globe|bulbus oculi|eye globe The core globe-shaped component of the camera-type eye. UBERON:0010231 anatomical line between outer ears biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010231 otic line|inter-otic line|inter-pinna line UBERON:0010233 stroma of thyroid gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010233 thyroid gland stroma|thyroid stroma The connective tissue that supports the lobules and follicles of the thyroid gland. UBERON:0010227 future cardiac atrium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010227 primordial cardiac atrium|primordial atrium|presumptive atrium heart tube Multi-tissue structure that is part of the heart tube and will become the cardiac atrium. UBERON:0010225 thalamic complex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010225 A nuclear complex which in mammals consists of four parts, the hypothalamus, epithalamus, ventral thalamus, and dorsal thalamus[WP,modified]. GO:1990666 PCSK9-LDLR complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990666 PCSK9/LDL-R complex|PCSK9:low-density lipoprotein receptor complex|PCSK9:EGF-A complex|PCSK9.LDLR complex A protein complex consisting of the serine protease PCSK9 (proprotein convertase subtilisin/kexin-9) and a low-density lipoprotein receptor (LDLR). Interaction typically occurs through the epidermal growth factor-like repeat A (EGF-A) domain of the LDLR, and complex formation promotes degradation of the LDLR through the endosome/lysosome pathway. CHEBI:76830 EC 5.99.1.* (miscellaneous isomerase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76830 GO:1990667 PCSK9-AnxA2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990667 PCSK9-Annexin A2 complex|PCSK9.AnxA2 complex|PCSK9:ANXA2 complex A protein complex consisting of the serine protease PCSK9 (proprotein convertase subtilisin/kexin-9) and annexin A2 (AnxA2). CHEBI:76831 EC 4.4.1.* (C-S lyase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76831 GO:1990668 vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990668 vesicle fusion with ER-Golgi intermediate compartment membrane|vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment membrane|vesicle fusion with ERGIC membrane|vesicle fusion with ER-Golgi intermediate compartment (ERGIC) membrane The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane of the ERGIC. This can involve anterograde or retrograde transport vesicles. GO:1990669 endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with endoplasmic reticulum membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990669 ER-Golgi intermediate compartment derived vesicle fusion with ER membrane|endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with ER membrane The joining of the lipid bilayer membrane around an ERGIC-derived vesicle to the lipid bilayer membrane of the ER. Such vesicles include COPI-coated transport vesicles involved in retrograde transport. CHEBI:76845 EC 1.14.18.* (oxidoreductase acting on paired donors, miscellaneous compound as one donor, incorporating 1 atom of oxygen) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76845 CHEBI:76846 7-deoxyloganetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76846 CHEBI:27836 dodecanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27836 CHEBI:76844 7-deoxyloganate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76844 CHEBI:76849 7-deoxyloganetin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76849 CHEBI:76847 EC 1.14.16.* (oxidoreductase acting on paired donors, reduced pteridine as one donor, incorporating 1 atom of oxygen) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76847 CHEBI:76848 EC 1.17.4.* (oxidoreductase acting on CH or CH2 with a disulfide as acceptor) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76848 CHEBI:62200 galactosyl-(glucosyl)2-(heptosyl)3-(KDO)2-lipid A-bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62200 CHEBI:62201 galactosyl-glucosyl-heptosyl-(phosphoheptosyl)2-(KDO)2-lipid A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62201 CHEBI:62205 3-methylxanthine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62205 CHEBI:62202 glucosyl-heptosyl-(phosphoheptosyl)2-(KDO)2-lipid A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62202 CHEBI:62203 glucosyl-(heptosyl)2-4-phosphoheptosyl-(KDO)2-lipid A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62203 CHEBI:62208 3-methyl-7H-xanthine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62208 CHEBI:62209 CoA-disulfide(8-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62209 CHEBI:62206 monomethylxanthine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62206 CHEBI:62207 3-methyl-9H-xanthine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62207 CHEBI:76841 EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76841 CHEBI:76842 vancomycin(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76842 CHEBI:76840 EC 1.14.99.* (miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76840 CHEBI:76856 3-(5-oxoisoxazolin-4-yl)-L-alanine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76856 CHEBI:76857 EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76857 CHEBI:27847 3-iodo-L-tyrosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27847 CHEBI:27848 alpha-L-rhamnoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27848 CHEBI:76855 3-(5-oxoisoxazolin-2-yl)-L-alanine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76855 CHEBI:27843 cyanidin cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27843 CHEBI:27844 2',3'-cyclic AMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27844 UBERON:0010291 layer of sclera biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010291 . UBERON:0010294 scleral endothelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010294 An endothelium that is part of a sclera. UBERON:0010295 substantia propria of sclera biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010295 subsantia propria|subsantia propria sclerae|scleral stroma|stroma of sclera|substantia propria sclerae A stroma that is part of a sclera. CHEBI:62211 3-butynoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62211 CHEBI:62212 5-hydroxypyrrole-2-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62212 CHEBI:62210 5-hydroxypyrrole-2-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62210 UBERON:0010299 scleral mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010299 Mesenchyme surrounding the developing optic cup which develops into the sclera. CHEBI:62215 allelochemical biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62215 CHEBI:62216 1-hydroxyphenazine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62216 CHEBI:62213 D-4-hydroxy-2-oxoglutarate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62213 CHEBI:62214 5-hydroxykynurenaminium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62214 GO:1990608 mitotic spindle pole body localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990608 spindle pole body localisation in nuclear envelope|establishment and maintenance of spindle pole body localization|spindle pole body localization in nuclear envelope|establishment of spindle pole body localisation|establishment of spindle pole body localization|spindle pole body positioning|mitotic spindle pole body localization to nuclear envelope|spindle pole body docking|spindle pole body localization to nuclear envelope A process in which a mitotic spindle pole body is transported to, or maintained in, a specific cellular location. CHEBI:62219 2-heptyl-4-quinolone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62219 GO:1990609 glutamate-cysteine ligase regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990609 Binds to and modulates the activity of glutamate-cysteine ligase. CHEBI:62217 23,24-dihydrocucurbitacin B biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62217 GO:1990604 IRE1-TRAF2-ASK1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990604 ERN1-TRAF2-ASK1 complex A protein complex of the endoplasmic reticulum membrane that consists of IRE1 (Inositol-requiring enzyme-1), TRAF2 (TNF receptor-associated factor 2) and ASK1 (Apoptosis signal-regulating kinase 1, a MAP3K). GO:1990605 GU repeat RNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990605 Interacting selectively and non-covalently with an RNA molecule containing GU repeats. GO:1990606 membrane scission GTPase motor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990606 Catalysis of the generation of a 'twisting' activity resulting in the scission of a membrane, coupled to the hydrolysis of a nucleoside triphosphate. GO:1990607 obsolete detection of stimulus involved in cytokinesis after mitosis checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990607 OBSOLETE. The series of events in which information about whether cytokinesis has correctly completed, is received and converted into a molecular signal, contributing to a cytokinesis after mitosis checkpoint. GO:1990600 single-stranded DNA endodeoxyribonuclease activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990600 Increases the activity of a single-stranded DNA endodeoxyribonuclease activator activity. CHEBI:76852 EC 1.2.1.* (oxidoreductase acting on donor aldehyde/oxo group with NAD(+) or NADP(+) as acceptor) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76852 CHEBI:27849 toluene-4-sulfonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27849 GO:1990601 5' overhang single-stranded DNA endodeoxyribonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990601 Catalysis of the hydrolysis of ester linkages within 5' overhang single-stranded deoxyribonucleic acid by creating internal breaks. CHEBI:76853 EC 1.2.3.* (oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76853 GO:1990602 obsolete importin alpha-subunit nuclear import complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990602 IntAct:EBI-9673795 Importin13-Mago-Tsu complex|Cdm-Mago-Tsu complex OBSOLETE. A trimeric protein complex which functions to transport the importin alpha-subunit into the nucleus through the nuclear pore to facilitate another round of mRNP incorporation and regulation. In Drosophila it consists of Cdm (Imp13), Mago and Tsu (Y14). GO:1990603 dark adaptation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990603 The process by which the rods of the retina gradually become fully responsive to dim light when no longer exposed to bright light. CHEBI:76851 isoxazolin-5-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76851 CHEBI:27812 Se-methyl-L-selenocysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27812 CHEBI:27814 12-dehydro-leukotriene B4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27814 GO:1990610 acetolactate synthase regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990610 Binds to and modulates the activity of acetolactate synthase. CHEBI:76866 EC 1.6.5.* (oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76866 UBERON:0009292 embryonic nasal process biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009292 nasal placode CHEBI:76869 EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD(+) or NADP(+) as acceptor) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76869 CHEBI:27810 resorcinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27810 CHEBI:27811 undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-D-isoglutaminyl-L-lysyl-D-alanyl-D-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27811 UBERON:0010285 midbrain basal plate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010285 basal plate midbrain|basal plate midbrain region Portion of tissue that is dorsolateral to the floor plate and part of the midbrain. UBERON:0010286 midbrain neural tube biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010286 Portion of neural tube that gives rise to the midbrain. CHEBI:62222 4-methyl-3-oxopentanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62222 CHEBI:13209 long-chain fatty acid ethyl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_13209 CHEBI:62223 2-(beta-D-glucosyloxy)-cis-cinnamate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62223 CHEBI:62220 pyocyanine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62220 CHEBI:62221 5-methylphenazine-1-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62221 CHEBI:62226 L-selenocystathionine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62226 CHEBI:62227 L-adenosylselenomethionine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62227 CHEBI:62224 (-)-7-epi-alpha-selinene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62224 CHEBI:62225 S-sulfo-L-cysteinate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62225 GO:1990619 histone H3-K9 deacetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990619 The modification of histone H3 by the removal of an acetyl group from lysine at position 9 of the histone. GO:1990615 Kelch-containing formin regulatory complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990615 Bud14-Kel1-Kel2 complex|KFRC complex A protein complex that regulates actin cable formation, polarized cell growth, and cytokinesis in a formin-dependent manner. In S. cerevisiae the complex is composed of Bud14p and two Kelch family proteins, Kel1p and Kel2p. GO:1990616 magnesium ion export from mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990616 magnesium ion efflux from mitochondrion The directed movement of magnesium ions out of mitochondrial matrix into the cytosol by means of some agent such as a transporter or pore. GO:1990617 CHOP-ATF4 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990617 CHOP-CREB-2 complex|ATF4-CHOP heterodimer|CHOP/ATF4 complex|CHOP-ATF4 heterodimer|GADD153-ATF4 complex A heterodimeric transcription factor complex that is composed of CHOP (C/EBP homology protein, GADD153) and ATF4 (activating transcription factor 4, also known as cAMP response element binding protein-2/CREB-2) subunits. GO:1990618 obsolete ANPR-A:ANP complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990618 IntAct:EBI-10093340 ANPR-A:ANP complex OBSOLETE. The ANPR-A:ANP complex is composed of the hormone AMP bound to the extracellular domain of ANPR-A domain. It is formed in the atrium in response to atrial distension (high blood volume) and leads to guanylate cyclase activity of the ANPR-A receptor, thereby elevating intracellular cGMP levels. The end result is a reduction in blood volume and, therefore, a reduction in cardiac output and systemic blood pressure. Therefore, ANPR-A:ANP complex plays a major role in the regulation of blood pressure and salt-fluid volume homeostasis. CHEBI:76863 EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76863 GO:1990611 regulation of cytoplasmic translational initiation in response to stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990611 Modulation of the frequency, rate or extent of cytoplasmic translational initiation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). GO:1990612 Sad1-Kms1 LINC complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990612 A LINC complex implicated in the connection of DNA double strand breaks to the cytoskeleton during DNA double-strand break repair. CHEBI:27817 alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GlcNAc-(1->3)-beta-Gal-(1->4)-beta-Glc-(1->1')-Cer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27817 CHEBI:76864 (2S,3S)-beta-methylphenylalanine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76864 CHEBI:76861 EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76861 GO:1990613 mitochondrial membrane fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990613 The joining of two lipid bilayers that surround the mitochondria. CHEBI:27819 clavaldehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27819 GO:1990614 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990614 CHEBI:27823 (5-hydroxyindol-3-yl)acetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27823 CHEBI:76878 EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76878 CHEBI:76879 EC 2.6.1.* (transaminase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76879 CHEBI:76876 EC 2.2.1.* (transketolase/transaldolase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76876 CHEBI:27825 3',5-dihydroxy-3,4',7-trimethoxyflavone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27825 GO:1990620 ANPR-A receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990620 IntAct:EBI-10093340 NPR1 receptor complex A receptor complex composed of two ANPR-A molecules and expressed in the heart atrium in mammals; it plays a major role in the regulation of blood pressure and salt-fluid volume homeostasis. Binding of the ligand AMP in response to atrial distension (high blood volume) leads to guanylate cyclase activity of the ANPR-A receptor complex, thereby elevating intracellular cGMP levels. The end result is a reduction in blood volume and, therefore, a reduction in cardiac output and systemic blood pressure. GO:1990621 ESCRT IV complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990621 IntAct:EBI-11565638 Vps4-Vta1 complex|VPS4A/B complex|vacuolar protein sorting-associated complex|Vps4 complex|Vta1-Vps4 complex|VPS4A-VPS4B|ESCRT-IV An ESCRT complex that has AAA-ATPase activity and is involved in ESCRT-mediated intralumenal vesicle formation and the final stages of cytokinesis. The complex catalyzes disassembly of the ESCRT III filament around the neck of the budding vesicle in an ATP-driven reaction, resulting in membrane scission and recycling of the ESCRT III components back to the cytosol. In yeast, it is formed by the AAA ATPase Vps4 and its cofactor Vta1. CHEBI:27826 (S)-4-hydroxymandelonitrile beta-D-glucoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27826 CHEBI:27820 prostaglandin A2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27820 CHEBI:27821 (S)-methylmalonaldehydic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27821 CHEBI:27822 2-aminobenzimidazole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27822 CHEBI:62230 GDP-alpha-D-glucose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62230 UBERON:0010272 hyoid apparatus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010272 apparatus hyoideus|hyolingual system|apparatus hyobranchialis|hyobranchial apparatus A group of bones comprised of hyoid body and two pairs of cornua (i.e. greater cornua and lesser cornua), and lies just below the tongue, above the thyroid cartilage UBERON:0010273 zone of hyoid bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010273 hyoid bone zone A zone of bone organ that is part of a hyoid bone. CHEBI:62233 undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-D-isoglutaminyl-L-lysyl-D-alanyl-D-alanine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62233 CHEBI:62234 undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-D-isoglutaminyl-(glycyl)-L-lysyl-D-alanyl-D-alanine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62234 UBERON:0010276 space in vertebral column biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010276 vertebral conduit|vertebral column opening Any anatomical space that is part of a vertebral column. CHEBI:62231 undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-D-isoglutaminyl-(glycyl)3-L-lysyl-D-alanyl-D-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62231 CHEBI:62232 undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-D-isoglutaminyl-(glycyl)-L-lysyl-D-alanyl-D-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62232 CHEBI:62237 cardiolipin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62237 CHEBI:62235 undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-D-isoglutaminyl-(glycyl)3-L-lysyl-D-alanyl-D-alanine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62235 CHEBI:62236 undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-D-isoglutaminyl-(glycyl)5-L-lysyl-D-alanyl-D-alanine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62236 CHEBI:62239 3-hydroxydecanoyl-3-hydroxydecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62239 GO:1990626 mitochondrial outer membrane fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990626 mitochondrion outer membrane fusion The membrane organization process that joins two mitochondrial outer membranes to form a single membrane. CHEBI:76870 EC 1.9.3.* (oxidoreductase acting on donor heme group, oxygen as acceptor) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76870 CHEBI:76871 EC 2.1.1.* (methyltransferases) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76871 GO:1990627 mitochondrial inner membrane fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990627 mitochondrion inner membrane fusion The membrane organization process that joins two mitochondrial inner membranes to form a single membrane. GO:1990628 obsolete Sigma-E factor negative regulation complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990628 IntAct:EBI-9019066 RseA-RseB-RpoE complex|Sigma-E factor negative regulation complex OBSOLETE. A protein complex consisting of RseA, RseB and RpoE. It form the inactive form of the sigma-E transcription factor. In response to stress, outer membrane proteins accumulate in the periplasm and activate cleavage of RseA periplasmic domain by DegS, triggering a proteolytic cascade that frees sigma-E to activate gene expression. RseB binding to RseA prevents activated DegS from cleaving RseA. Sigma-E-mediated envelope stress response is the major pathway to ensure homeostasis in the envelope compartment of the cell. GO:1990629 phospholamban complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990629 IntAct:EBI-10104734 cardiac phospholamban complex|cardiac PLN complex|cardiac PLB complex A protein complex found as a homopentamer of the phospholamban (PLN) protein in the sarcoplasmic reticulum (SR) membrane of cardiomyocytes. Cardiac PLN is a main determinant of muscle contraction and relaxation, by regulating intracellular calcium levels. GO:1990622 CHOP-ATF3 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990622 GADD153-ATF3 complex|ATF3-CHOP complex|CHOP-ATF3 heterodimeric complex|CHOP-ATF3 heterodimer A heterodimeric protein complex that is composed of CHOP (C/EBP homology protein, GADD153) and ATF3 (activating transcription factor 3) subunits. CHEBI:27827 paraoxon biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27827 CHEBI:76874 EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76874 GO:1990623 Herring body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990623 neurosecretory body The dilated terminal portions of neurosecretory axons constituting the hypothalamohypophyseal tract, found in close proximity to sinusoidal capillaries in the posterior pituitary. Herring bodies consist of aggregates of membrane-bound neurosecretory vesicles where oxytocin or antidiuretic hormone (ADH) are stored prior to release. Each Herring body also contains ATP and either neurophysin I or neurophysin II which bind to oxytocin and ADH, respectively. GO:1990624 guanyl nucleotide exchange factor inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990624 Stops, prevents or reduces the activity of a guanyl nucleotide exchange factor. CHEBI:76872 2-iminobutanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76872 GO:1990625 negative regulation of cytoplasmic translational initiation in response to stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990625 Any process that stops, prevents or reduces the rate of cytoplasmic translation initiation as a result of a stimulus indicating the organism is under stress. GO:0050268 coniferyl-alcohol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050268 RHEA:22444|MetaCyc:RXN-2602|EC:1.1.1.194 coniferyl-alcohol:NADP+ oxidoreductase activity Catalysis of the reaction: coniferyl alcohol + NADP+ = coniferyl aldehyde + NADPH. GO:0050269 coniferyl-aldehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050269 MetaCyc:RXN-1241|EC:1.2.1.68 coniferyl aldehyde:NAD(P)+ oxidoreductase activity Catalysis of the reaction: coniferyl aldehyde + H2O + NAD(P)+ = ferulate + NAD(P)H + H+. GO:0050266 rosmarinate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050266 RHEA:22344|EC:2.3.1.140|MetaCyc:ROSMARINATE-SYNTHASE-RXN caffeoyl-coenzyme A:3,4-dihydroxyphenyllactic acid caffeoyltransferase activity|rosmarinic acid synthase activity|caffeoyl-CoA:3-(3,4-dihydroxyphenyl)lactate 2'-O-caffeoyl-transferase activity|4-coumaroyl-CoA:4-hydroxyphenyllactic acid 4-coumaroyl transferase activity Catalysis of the reaction: caffeoyl-CoA + 3-(3,4-dihydroxyphenyl)lactate = CoA + rosmarinate. GO:0050267 rubber cis-polyprenylcistransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050267 EC:2.5.1.20|RHEA:18801|MetaCyc:2.5.1.20-RXN rubber allyltransferase activity|cis-prenyl transferase activity|rubber polymerase activity|rubber prenyltransferase activity|rubber transferase activity|isopentenyl pyrophosphate cis-1,4-polyisoprenyl transferase activity|poly-cis-polyprenyl-diphosphate:isopentenyl-diphosphate polyprenylcistransferase activity Catalysis of the reaction: poly-cis-polyprenyl diphosphate + isopentenyl diphosphate = diphosphate + a poly-cis-polyprenyl diphosphate longer by one C5 unit. GO:0015939 pantothenate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015939 pantothenate metabolism|vitamin B5 metabolism|vitamin B5 metabolic process The chemical reactions and pathways involving pantothenate, the anion of pantothenic acid, the amide of beta-alanine and pantoic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods. GO:1902018 negative regulation of cilium assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902018 down-regulation of cilium biogenesis|negative regulation of cilium biogenesis|down-regulation of ciliogenesis|down regulation of cilium assembly|negative regulation of ciliogenesis|downregulation of cilium assembly|inhibition of cilium biogenesis|downregulation of ciliogenesis|down regulation of cilium biogenesis|down-regulation of cilium assembly|down regulation of ciliogenesis|downregulation of cilium biogenesis|inhibition of ciliogenesis|inhibition of cilium assembly Any process that stops, prevents or reduces the frequency, rate or extent of cilium assembly. GO:1902019 regulation of cilium-dependent cell motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902019 regulation of cilium cell motility|regulation of ciliary cell motility Any process that modulates the frequency, rate or extent of cilium-dependent cell motility. GO:1902016 poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902016 poly(glucosyl N-acetylgalactosamine 1-phosphate) teichoic acid biosynthesis|poly(glucosyl N-acetylgalactosamine 1-phosphate) teichoic acid biosynthetic process|poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid anabolism|poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid synthesis|poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid formation|poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid biosynthesis The chemical reactions and pathways resulting in the formation of poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid. GO:1902017 regulation of cilium assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902017 regulation of ciliogenesis|regulation of cilium biogenesis Any process that modulates the frequency, rate or extent of cilium assembly. GO:1902014 poly(glycerol phosphate) teichoic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902014 poly(glycerol phosphate) teichoic acid anabolism|poly(glycerol phosphate) teichoic acid synthesis|poly(glycerol phosphate) teichoic acid formation|poly(glycerol phosphate) teichoic acid biosynthesis The chemical reactions and pathways resulting in the formation of poly(glycerol phosphate) teichoic acid. GO:0015935 small ribosomal subunit biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0015935 ribosomal small subunit The smaller of the two subunits of a ribosome. GO:0015936 coenzyme A metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015936 coenzyme A metabolism|CoA metabolism The chemical reactions and pathways involving coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester. GO:1902015 poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902015 poly(glucosyl N-acetylgalactosamine 1-phosphate) teichoic acid metabolic process|poly(glucosyl N-acetylgalactosamine 1-phosphate) teichoic acid metabolism|poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid metabolism The chemical reactions and pathways involving poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid. GO:0015937 coenzyme A biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015937 MetaCyc:PWY-4221|MetaCyc:COA-PWY|MetaCyc:PANTOSYN-PWY coenzyme A anabolism|coenzyme A synthesis|coenzyme A biosynthesis|coenzyme A formation|CoA biosynthesis The chemical reactions and pathways resulting in the formation of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester. GO:1902012 poly(ribitol phosphate) teichoic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902012 poly(ribitol phosphate) teichoic acid anabolism|poly(ribitol phosphate) teichoic acid synthesis|poly(ribitol phosphate) teichoic acid formation|poly(ribitol phosphate) teichoic acid biosynthesis The chemical reactions and pathways resulting in the formation of poly(ribitol phosphate) teichoic acid. GO:0015938 coenzyme A catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015938 coenzyme A breakdown|coenzyme A catabolism|CoA catabolism|coenzyme A degradation The chemical reactions and pathways resulting in the breakdown of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester. GO:1902013 poly(glycerol phosphate) teichoic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902013 poly(glycerol phosphate) teichoic acid metabolism The chemical reactions and pathways involving poly(glycerol phosphate) teichoic acid. GO:1902021 regulation of bacterial-type flagellum-dependent cell motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902021 regulation of bacterial-type flagellar cell motility|regulation of bacterial-type flagellum cell motility|regulation of flagellin-based flagellar cell motility Any process that modulates the frequency, rate or extent of bacterial-type flagellum-dependent cell motility. GO:0015931 nucleobase-containing compound transport biolink:BiologicalProcess go-plus goslim_pir|goslim_yeast http://purl.obolibrary.org/obo/GO_0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport The directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015932 nucleobase-containing compound transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015932 nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity Enables the transfer of nucleobases, nucleosides, nucleotides and nucleic acids from one side of a membrane to the other. GO:1902022 L-lysine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902022 The directed movement of a L-lysine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015933 obsolete flavin-containing electron transporter biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015933 flavin-containing electron transporter OBSOLETE. An oxidoreductase which contains either flavin-adenine dinucleotide or flavin mononucleotide as a prosthetic group, utilizes either NADH or NADPH and transfers electrons to other electron transfer proteins. GO:1902020 negative regulation of cilium-dependent cell motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902020 down regulation of ciliary cell motility|negative regulation of ciliary cell motility|downregulation of ciliary cell motility|negative regulation of cilium cell motility|down-regulation of ciliary cell motility|inhibition of ciliary cell motility Any process that stops, prevents or reduces the frequency, rate or extent of cilium-dependent cell motility. GO:0015934 large ribosomal subunit biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0015934 ribosomal large subunit The larger of the two subunits of a ribosome. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). GO:0015930 glutamate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015930 Catalysis of the formation of L-glutamine and 2-oxoglutarate from L-glutamate, using NADH, NADPH or ferredoxin as hydrogen acceptors. GO:0050260 ribose-5-phosphate-ammonia ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050260 KEGG_REACTION:R01053|MetaCyc:RIBOSE-5-PHOSPHATE--AMMONIA-LIGASE-RXN|EC:6.3.4.7|RHEA:13777 ribose 5-phosphate aminotransferase activity|5-phosphoribosylamine synthetase activity|ammonia-ribose 5-phosphate aminotransferase activity|ribose-5-phosphate:ammonia ligase (ADP-forming) Catalysis of the reaction: D-ribose 5-phosphate + ATP + NH(4)(+) = 5-phospho-D-ribosylamine + ADP + 2 H(+) + phosphate. CHEBI:37273 cis-11-tetradecenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37273 GO:0050261 ribose isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050261 KEGG_REACTION:R01081|MetaCyc:RIBOSE-ISOMERASE-RXN|RHEA:20796|EC:5.3.1.20 D-ribose ketol-isomerase activity|D-ribose aldose-ketose-isomerase activity|D-ribose isomerase activity Catalysis of the reaction: ribofuranose = D-ribulose. CHEBI:37274 trans-11-tetradecenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37274 CHEBI:37271 trans-2-tetradecenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37271 GO:0050264 rifamycin-B oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050264 MetaCyc:RIFAMYCIN-B-OXIDASE-RXN|EC:1.10.3.6|RHEA:11292|KEGG_REACTION:R03736 rifamycin-B:oxygen oxidoreductase activity|rifamycin B oxidase activity|rifamycin-B-oxidase activity Catalysis of the reaction: 2 H(+) + O(2) + rifamycin B = H(2)O(2) + rifamycin O. GO:0050265 RNA uridylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050265 MetaCyc:RNA-URIDYLYLTRANSFERASE-RXN|RHEA:14785|EC:2.7.7.52|Reactome:R-HSA-8941312 polynucleotide uridylyltransferase activity|UTP:RNA uridylyltransferase activity|TUT activity|poly(U) polymerase activity|terminal uridylyltransferase activity Catalysis of the reaction: UTP + RNA(n) = diphosphate + RNA(n+1). GO:0050262 ribosylnicotinamide kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050262 Reactome:R-HSA-8869627|Reactome:R-HSA-8869633|MetaCyc:RIBOSYLNICOTINAMIDE-KINASE-RXN|KEGG_REACTION:R02324|EC:2.7.1.22|RHEA:14017 nicotinamide riboside kinase activity|ribosylnicotinamide kinase (phosphorylating)|ATP:N-ribosylnicotinamide 5'-phosphotransferase activity Catalysis of the reaction: N-ribosylnicotinamide + ATP = ADP + 2 H(+) + nicotinamide mononucleotide. GO:0050263 ribosylpyrimidine nucleosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050263 EC:3.2.2.8|MetaCyc:RIBOSYLPYRIMIDINE-NUCLEOSIDASE-RXN|RHEA:56816 nucleoside ribohydrolase activity|N-ribosylpyrimidine ribohydrolase activity|pyrimidine-nucleoside ribohydrolase activity|RihB|YeiK|N-ribosylpyrimidine nucleosidase activity|pyrimidine nucleosidase activity Catalysis of the reaction: an N-D-ribosylpyrimidine + H2O = D-ribose + a pyrimidine. CHEBI:37276 (1-hydroxycyclohexyl)acetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37276 GO:0001301 progressive alteration of chromatin involved in cell aging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001301 progressive alteration of chromatin during cell aging|progressive alteration of chromatin during cell ageing|age-dependent accumulation of genetic damage Any chromatin organization process that occurs during the lifespan of the cell that results in changes in chromatin structure. Such changes may lead to gene dysregulation and ultimately to a loss in cell homeostasis, bringing about an aging phenotype. GO:0050279 sepiapterin deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050279 EC:3.5.4.24|MetaCyc:SEPIAPTERIN-DEAMINASE-RXN|RHEA:14025 sepiapterin aminohydrolase activity Catalysis of the reaction: sepiapterin + H2O = xanthopterin-B2 + NH3. GO:0001302 obsolete replicative cell aging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001302 replicative cell ageing OBSOLETE. The process associated with progression of the cell from its inception to the end of its lifespan that occurs as the cell continues cycles of growth and division. GO:0050277 sedoheptulokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050277 KEGG_REACTION:R01844|RHEA:23844|EC:2.7.1.14|MetaCyc:SEDOHEPTULOKINASE-RXN|Reactome:R-HSA-8959719 ATP:sedoheptulose 7-phosphotransferase activity|heptulokinase activity|sedoheptulokinase (phosphorylating) Catalysis of the reaction: ATP + sedoheptulose = ADP + 2 H(+) + sedoheptulose 7-phosphate. GO:0001303 obsolete nucleolar fragmentation involved in replicative aging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001303 nucleolar fragmentation during replicative ageing|nucleolar fragmentation during replicative aging OBSOLETE. A nucleolar fragmentation process that gives rise to multiple rounded structures and that occurs in conjunction with increasing age in dividing cells. GO:0050278 sedoheptulose-bisphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050278 EC:3.1.3.37|MetaCyc:SEDOHEPTULOSE-BISPHOSPHATASE-RXN|RHEA:17461 SBPase activity|sedoheptulose-1,7-bisphosphatase activity|sedoheptulose diphosphatase activity|sedoheptulose bisphosphatase activity|sedoheptulose-1,7-bisphosphate 1-phosphohydrolase activity|sedoheptulose 1,7-diphosphate phosphatase activity|sedoheptulose 1,7-diphosphatase activity|sedoheptulose 1,7-bisphosphatase activity Catalysis of the reaction: sedoheptulose 1,7-bisphosphate + H2O = sedoheptulose 7-phosphate + phosphate. GO:0001304 obsolete progressive alteration of chromatin involved in replicative cell aging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001304 progressive alteration of chromatin during replicative cell ageing|progressive alteration of chromatin during replicative cell aging OBSOLETE. A process that results in changes in chromatin structure contributing to replicative cell aging. CHEBI:37291 (3S)-3-isopropenyl-6-oxoheptanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37291 CHEBI:37292 1-(phosphoribosyl)imidazole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37292 GO:0001300 obsolete chronological cell aging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001300 chronological cell ageing OBSOLETE. The process associated with progression of the cell from its inception to the end of its lifespan that occurs when the cell is in a non-dividing, or quiescent, state. CHEBI:37290 1-(phosphoribosyl)imidazolecarboxamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37290 GO:1902029 positive regulation of histone H3-K18 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902029 positive regulation of histone H3 acetylation at K18|upregulation of histone H3K18 acetylation|activation of histone H3 acetylation at K18|upregulation of histone H3-K18 acetylation|up-regulation of histone H3 acetylation at K18|up regulation of histone H3K18 acetylation|positive regulation of histone H3K18 acetylation|up-regulation of histone H3-K18 acetylation|activation of histone H3-K18 acetylation|upregulation of histone H3 acetylation at K18|activation of histone H3K18 acetylation|up-regulation of histone H3K18 acetylation|up regulation of histone H3 acetylation at K18|up regulation of histone H3-K18 acetylation Any process that activates or increases the frequency, rate or extent of histone H3-K18 acetylation. GO:1902027 positive regulation of cartilage condensation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902027 up regulation of cartilage condensation|upregulation of cartilage condensation|up-regulation of cartilage condensation|activation of cartilage condensation Any process that activates or increases the frequency, rate or extent of cartilage condensation. GO:1902028 regulation of histone H3-K18 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902028 regulation of histone H3K18 acetylation|regulation of histone H3 acetylation at K18 Any process that modulates the frequency, rate or extent of histone H3-K18 acetylation. GO:1902025 nitrate import biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902025 nitrate influx|nitrate uptake The directed movement of nitrate into a cell or organelle. GO:0015946 methanol oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015946 MetaCyc:CO2FORM-PWY The chemical reactions and pathways resulting in the conversion of methanol to methyl-Coenzyme M. GO:0015947 methane metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015947 methane metabolism The chemical reactions and pathways involving methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes. GO:1902026 regulation of cartilage condensation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902026 Any process that modulates the frequency, rate or extent of cartilage condensation. GO:1902023 L-arginine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902023 L-arginine uptake|L-arginine import The directed movement of a L-arginine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015948 methanogenesis biolink:BiologicalProcess go-plus goslim_pir|goslim_metagenomics http://purl.obolibrary.org/obo/GO_0015948 Wikipedia:Methanogenesis|UM-BBD_pathwayID:meth methane biosynthesis|methane biosynthetic process The chemical reactions and pathways resulting in the formation of methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes. GO:0015949 nucleobase-containing small molecule interconversion biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0015949 MetaCyc:P1-PWY The chemical reactions and pathways by which a nucleobase, nucleoside or nucleotide small molecule is synthesized from another nucleobase, nucleoside or nucleotide small molecule. GO:1902024 L-histidine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902024 The directed movement of a L-histidine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:1902032 obsolete regulation of transcription from RNA polymerase II promoter involved in response to osmotic stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902032 regulation of gene-specific transcription from RNA polymerase II promoter involved in response to osmotic stress|regulation of transcription from Pol II promoter involved in osmotic stress response|regulation of transcription from RNA polymerase II promoter involved in response to osmotic stress|global transcription regulation from Pol II promoter involved in response to osmotic stress|regulation of transcription from RNA polymerase II promoter involved in osmotic stress response|regulation of transcription from RNA polymerase II promoter, global involved in osmotic response|regulation of global transcription from Pol II promoter involved in osmotic response|regulation of transcription from RNA polymerase II promoter involved in osmotic response|regulation of transcription from RNA polymerase II promoter, global involved in response to osmotic stress|regulation of transcription from Pol II promoter involved in osmotic response|regulation of global transcription from Pol II promoter involved in osmotic stress response|regulation of global transcription from Pol II promoter involved in response to osmotic stress|regulation of transcription from RNA polymerase II promoter, global involved in osmotic stress response|regulation of transcription from Pol II promoter involved in response to osmotic stress|regulation of gene-specific transcription from RNA polymerase II promoter involved in osmotic response|global transcription regulation from Pol II promoter involved in osmotic response|global transcription regulation from Pol II promoter involved in osmotic stress response|regulation of gene-specific transcription from RNA polymerase II promoter involved in osmotic stress response OBSOLETE. Any regulation of transcription from RNA polymerase II promoter that is involved in response to osmotic stress. GO:0015942 formate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015942 formate metabolism The chemical reactions and pathways involving formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid. GO:0015943 formate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015943 formic acid biosynthetic process|formic acid biosynthesis|formate anabolism|formate synthesis|formate formation|formate biosynthesis The chemical reactions and pathways resulting in the formation of formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid. GO:1902033 regulation of hematopoietic stem cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902033 regulation of hemopoietic stem cell proliferation Any process that modulates the frequency, rate or extent of hematopoietic stem cell proliferation. GO:0015944 formate oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015944 MetaCyc:PWY-1881 formic acid oxidation The chemical reactions and pathways by which formate is converted to CO2. GO:1902030 negative regulation of histone H3-K18 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902030 down regulation of histone H3 acetylation at K18|down-regulation of histone H3-K18 acetylation|downregulation of histone H3 acetylation at K18|inhibition of histone H3K18 acetylation|downregulation of histone H3-K18 acetylation|negative regulation of histone H3 acetylation at K18|down-regulation of histone H3 acetylation at K18|down regulation of histone H3-K18 acetylation|inhibition of histone H3-K18 acetylation|down regulation of histone H3K18 acetylation|downregulation of histone H3K18 acetylation|inhibition of histone H3 acetylation at K18|negative regulation of histone H3K18 acetylation|down-regulation of histone H3K18 acetylation Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K18 acetylation. GO:1902031 regulation of NADP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902031 regulation of oxidized nicotinamide adenine dinucleotide phosphate metabolic process|regulation of oxidized NADP metabolic process|regulation of NADPH metabolic process|regulation of reduced NADP metabolic process|regulation of NADP metabolism|regulation of reduced NADP metabolism|regulation of NADPH metabolism|regulation of oxidized NADP metabolism|regulation of oxidized nicotinamide adenine dinucleotide phosphate metabolism|regulation of NADP (oxidized) metabolism|regulation of reduced nicotinamide adenine dinucleotide phosphate metabolism|regulation of nicotinamide adenine dinucleotide phosphate metabolism|regulation of NADP (reduced) metabolic process|regulation of NAD phosphorylation and dephosphorylation|regulation of NADP (reduced) metabolism|regulation of nicotinamide adenine dinucleotide phosphate metabolic process|regulation of reduced nicotinamide adenine dinucleotide phosphate metabolic process|regulation of NADP (oxidized) metabolic process Any process that modulates the frequency, rate or extent of NADP metabolic process. GO:0015945 methanol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015945 methanol metabolism The chemical reactions and pathways involving methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent. GO:0015940 pantothenate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015940 MetaCyc:PWY-3961|MetaCyc:PANTO-PWY|MetaCyc:PWY-4221|MetaCyc:PANTOSYN-PWY pantothenate anabolism|pantothenate synthesis|pantothenate biosynthesis|pantothenate anabolism from valine|pantothenate formation|vitamin B5 biosynthesis|pantothenate synthesis from valine|vitamin B5 biosynthetic process|pantothenate biosynthesis from valine|pantothenate biosynthetic process from valine|pantothenate formation from valine|pantothenate anabolism from 2-oxypantoyl lactone|pantothenate synthesis from 2-oxypantoyl lactone|pantothenate biosynthesis from 2-oxypantoyl lactone|pantothenate biosynthetic process from 2-oxypantoyl lactone|pantothenate formation from 2-oxypantoyl lactone|pantothenate biosynthetic process from 2-dehydropantolactone The chemical reactions and pathways resulting in the formation of pantothenate, the anion of pantothenic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods. GO:0015941 pantothenate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015941 pantothenate catabolism|vitamin B5 catabolism|pantothenate degradation|pantothenate breakdown|vitamin B5 catabolic process The chemical reactions and pathways resulting in the breakdown of pantothenate, the anion of pantothenic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods. GO:0001309 obsolete age-dependent telomere shortening biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001309 age-dependent telomere shortening OBSOLETE. Progressive reduction in length of the telomeres, the termini of eukaryotic chromosomes, that occurs as part of the cellular aging process. GO:0050271 S-alkylcysteine lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050271 RHEA:22424|MetaCyc:S-ALKYLCYSTEINE-LYASE-RXN|EC:4.4.1.6 S-alkyl-L-cysteine alkylthiol-lyase (deaminating) activity|alkyl cysteine lyase activity|S-alkyl-L-cysteine alkylthiol-lyase (deaminating; pyruvate-forming)|alkylcysteine lyase activity|S-alkyl-L-cysteine lyase activity|S-alkyl-L-cysteine sulfoxide lyase activity|S-alkyl-L-cysteinase activity|S-alkylcysteinase activity Catalysis of the reaction: an S-alkyl-L-cysteine + H2O = an alkyl thiol + NH3 + pyruvate. GO:0050272 S-carboxymethylcysteine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050272 RHEA:22868|EC:4.5.1.5|KEGG_REACTION:R04003|MetaCyc:S-CARBOXYMETHYLCYSTEINE-SYNTHASE-RXN 3-chloro-L-alanine chloride-lyase (adding thioglycolate)|S-carboxymethyl-L-cysteine synthase activity|3-chloro-L-alanine chloride-lyase (adding thioglycolate; S-carboxymethyl-L-cysteine-forming) Catalysis of the reaction: 3-chloro-L-alanine + thioglycolate = S-carboxymethyl-L-cysteine + chloride + H(+). GO:0050270 S-adenosylhomocysteine deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050270 RHEA:20716|EC:3.5.4.28|KEGG_REACTION:R00193|MetaCyc:S-ADENOSYLHOMOCYSTEINE-DEAMINASE-RXN adenosylhomocysteine deaminase activity|S-adenosyl-L-homocysteine aminohydrolase activity Catalysis of the reaction: S-adenosyl-L-homocysteine + H(2)O + H(+) = S-inosyl-L-homocysteine + NH(4)(+). CHEBI:37283 heptanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37283 GO:0050275 scopoletin glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050275 RHEA:20453|EC:2.4.1.128|KEGG_REACTION:R03594|MetaCyc:SCOPOLETIN-GLUCOSYLTRANSFERASE-RXN UDP-glucose:scopoletin O-beta-D-glucosyltransferase activity|uridine diphosphoglucose-scopoletin glucosyltransferase activity|UDPglucose:scopoletin O-beta-D-glucosyltransferase activity|UDPglucose:scopoletin glucosyltransferase activity|SGTase activity Catalysis of the reaction: scopoletin + UDP-D-glucose = H(+) + scopolin + UDP. GO:0001305 obsolete progressive alteration of chromatin involved in chronological cell aging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001305 progressive alteration of chromatin during chronological cell aging|progressive alteration of chromatin during chronological cell ageing OBSOLETE. A process that results in changes in chromatin structure contributing to chronological cell aging, occurring in non-dividing cells. GO:0050276 scyllo-inosamine 4-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050276 MetaCyc:SCYLLO-INOSAMINE-KINASE-RXN|RHEA:18605|EC:2.7.1.65|KEGG_REACTION:R03384 ATP:inosamine phosphotransferase activity|scyllo-inosamine kinase activity|scyllo-inosamine kinase (phosphorylating)|ATP:1-amino-1-deoxy-scyllo-inositol 4-phosphotransferase activity Catalysis of the reaction: 1-amino-1-deoxy-scyllo-inositol + ATP = 1-amino-1-deoxy-scyllo-inositol 4-phosphate + ADP + 2 H(+). GO:0001306 age-dependent response to oxidative stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001306 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, where the change varies according to the age of the cell or organism. GO:0050273 S-succinylglutathione hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050273 EC:3.1.2.13|KEGG_REACTION:R00499|MetaCyc:S-SUCCINYLGLUTATHIONE-HYDROLASE-RXN|RHEA:16713 Catalysis of the reaction: S-succinylglutathione + H(2)O = glutathione + H(+) + succinate. GO:0001307 obsolete extrachromosomal circular DNA accumulation involved in replicative cell aging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001307 extrachromosomal circular DNA accumulation during replicative cell ageing|extrachromosomal circular DNA accumulation during replicative cell aging OBSOLETE. Increase in abundance of circular DNA molecules in dividing cells as they age. These molecules originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats, and then replicated independently of chromosomal replication. GO:0050274 salicyl-alcohol beta-D-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050274 KEGG_REACTION:R03558|RHEA:11512|MetaCyc:SALICYL-ALCOHOL-GLUCOSYLTRANSFERASE-RXN|EC:2.4.1.172 salicyl-alcohol b-D-glucosyltransferase activity|UDPglucose:salicyl-alcohol beta-D-glucosyltransferase activity|UDPglucose:salicyl alcohol phenyl-glucosyltransferase activity|salicyl-alcohol glucosyltransferase activity|uridine diphosphoglucose-salicyl alcohol 2-glucosyltransferase activity|UDP-glucose:salicyl-alcohol beta-D-glucosyltransferase activity Catalysis of the reaction: salicyl alcohol + UDP-D-glucose = H(+) + salicin + UDP. GO:0001308 obsolete negative regulation of chromatin silencing involved in replicative cell aging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001308 loss of chromatin silencing during replicative cell ageing|loss of chromatin silencing involved in replicative cell aging OBSOLETE. The process, which occurs as a dividing cell ages, leading to expression of genes that are typically not expressed due to silencing by regulatory proteins. CHEBI:37287 (3R)-3-isopropenyl-6-oxoheptanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37287 GO:0050288 sorbose dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050288 MetaCyc:SORBOSE-DEHYDROGENASE-RXN|EC:1.1.99.12|RHEA:14713|KEGG_REACTION:R01696 L-sorbose:acceptor 5-oxidoreductase activity|L-sorbose:(acceptor) 5-oxidoreductase activity Catalysis of the reaction: L-sorbose + A = 5-dehydro-D-fructose + AH(2). GO:0050289 spermidine dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050289 RHEA:14273|EC:1.5.99.6|MetaCyc:SPERMIDINE-DEHYDROGENASE-RXN spermidine:(acceptor) oxidoreductase activity|spermidine:acceptor oxidoreductase activity Catalysis of the reaction: spermidine + acceptor + H2O = 1,3-diaminopropane + 4-aminobutanal + reduced acceptor. CHEBI:52897 sphingosylphosphocholine acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52897 GO:0015917 aminophospholipid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015917 The directed movement of aminophospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aminophospholipids contain phosphoric acid as a mono- or diester and an amino (NH2) group. GO:0015918 sterol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015918 The directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. GO:1902038 positive regulation of hematopoietic stem cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902038 up-regulation of hematopoietic stem cell differentiation|positive regulation of haemopoietic stem cell differentiation|activation of haematopoietic stem cell differentiation|up-regulation of haematopoietic stem cell differentiation|up regulation of haemopoietic stem cell differentiation|up regulation of hemopoietic stem cell differentiation|activation of hemopoietic stem cell differentiation|positive regulation of hemopoietic stem cell differentiation|upregulation of hematopoietic stem cell differentiation|upregulation of haemopoietic stem cell differentiation|positive regulation of haematopoietic stem cell differentiation|up regulation of haematopoietic stem cell differentiation|up regulation of hematopoietic stem cell differentiation|up-regulation of hemopoietic stem cell differentiation|activation of hematopoietic stem cell differentiation|up-regulation of haemopoietic stem cell differentiation|activation of haemopoietic stem cell differentiation|upregulation of hemopoietic stem cell differentiation|upregulation of haematopoietic stem cell differentiation Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell differentiation. GO:0015919 peroxisomal membrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015919 The directed movement of substances to, from or across the peroxisomal membrane. GO:1902039 negative regulation of seed dormancy process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902039 downregulation of seed dormancy|down regulation of seed dormancy process|down-regulation of seed dormancy|negative regulation of seed dormancy|downregulation of seed dormancy process|inhibition of seed dormancy|down-regulation of seed dormancy process|inhibition of seed dormancy process|down regulation of seed dormancy Any process that stops, prevents or reduces the frequency, rate or extent of seed dormancy process. GO:1902036 regulation of hematopoietic stem cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902036 regulation of hemopoietic stem cell differentiation|regulation of haemopoietic stem cell differentiation|regulation of haematopoietic stem cell differentiation Any process that modulates the frequency, rate or extent of hematopoietic stem cell differentiation. GO:0015913 short-chain fatty acid import biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015913 short-chain fatty acid uptake The directed movement of short-chain fatty acids into a cell or organelle. Short-chain fatty acids are fatty acids with a chain length of less than C6. GO:1902037 negative regulation of hematopoietic stem cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902037 inhibition of hematopoietic stem cell differentiation|downregulation of hemopoietic stem cell differentiation|downregulation of haemopoietic stem cell differentiation|down regulation of hematopoietic stem cell differentiation|down-regulation of hemopoietic stem cell differentiation|down regulation of haemopoietic stem cell differentiation|negative regulation of hemopoietic stem cell differentiation|down-regulation of haematopoietic stem cell differentiation|negative regulation of haematopoietic stem cell differentiation|inhibition of haemopoietic stem cell differentiation|downregulation of hematopoietic stem cell differentiation|inhibition of hemopoietic stem cell differentiation|downregulation of haematopoietic stem cell differentiation|down regulation of haematopoietic stem cell differentiation|down-regulation of hematopoietic stem cell differentiation|inhibition of haematopoietic stem cell differentiation|down regulation of hemopoietic stem cell differentiation|down-regulation of haemopoietic stem cell differentiation|negative regulation of haemopoietic stem cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell differentiation. GO:0015914 phospholipid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015914 The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phospholipids are any lipids containing phosphoric acid as a mono- or diester. GO:1902034 negative regulation of hematopoietic stem cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902034 down-regulation of hemopoietic stem cell proliferation|down regulation of hematopoietic stem cell proliferation|negative regulation of hemopoietic stem cell proliferation|downregulation of hematopoietic stem cell proliferation|inhibition of hemopoietic stem cell proliferation|down-regulation of hematopoietic stem cell proliferation|down regulation of hemopoietic stem cell proliferation|inhibition of hematopoietic stem cell proliferation|downregulation of hemopoietic stem cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell proliferation. GO:0015915 fatty-acyl group transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015915 fatty acyl transport The directed movement of fatty acyl groups into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A fatty acyl group is any acyl group derived from a fatty acid. GO:0015916 fatty-acyl-CoA transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015916 fatty acyl-CoA transport|fatty acyl coenzyme A transport|fatty acyl CoA transport The directed movement of fatty acyl coenzyme A into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fatty acyl coenzyme A is an acyl group linked to 3'-phosphoadenosine-(5')diphospho(4')pantatheine (coenzyme A). GO:1902035 positive regulation of hematopoietic stem cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902035 activation of hemopoietic stem cell proliferation|positive regulation of hemopoietic stem cell proliferation|upregulation of hematopoietic stem cell proliferation|up regulation of hematopoietic stem cell proliferation|up-regulation of hemopoietic stem cell proliferation|activation of hematopoietic stem cell proliferation|upregulation of hemopoietic stem cell proliferation|up-regulation of hematopoietic stem cell proliferation|up regulation of hemopoietic stem cell proliferation Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell proliferation. GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902043 activation of death receptor-mediated apoptosis|upregulation of extrinsic apoptotic signaling pathway via death domain receptors|up-regulation of death receptor-mediated apoptosis|up-regulation of extrinsic apoptotic signaling pathway via death domain receptors|activation of extrinsic apoptotic signaling pathway via death domain receptors|upregulation of death receptor-mediated apoptosis|up regulation of extrinsic apoptotic signaling pathway via death domain receptors|up regulation of death receptor-mediated apoptosis|positive regulation of death receptor-mediated apoptosis Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors. CHEBI:37259 3-oxopimelic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37259 GO:0015910 long-chain fatty acid import into peroxisome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015910 peroxisomal long-chain fatty acid uptake|peroxisomal long-chain fatty acid import The directed movement of long-chain fatty acids into a peroxisome. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22. GO:1902044 regulation of Fas signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902044 regulation of FasL signaling pathway|regulation of Fas-FasL signaling pathway|regulation of FAS ligand-Fas signaling pathway|regulation of Fas receptor signaling pathway|regulation of Apo-1 signaling pathway|regulation of CD95 signaling pathway|regulation of FasR signaling pathway Any process that modulates the frequency, rate or extent of Fas signaling pathway. GO:0015911 long-chain fatty acid import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015911 plasma membrane long-chain fatty acid transport The directed movement of long-chain fatty acids from outside of a cell, across the plasma membrane and into the cytosol. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22. CHEBI:37257 phytanate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37257 GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902041 regulation of death receptor-mediated apoptosis Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors. GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902042 down regulation of extrinsic apoptotic signaling pathway via death domain receptors|inhibition of extrinsic apoptotic signaling pathway via death domain receptors|inhibition of death receptor-mediated apoptosis|down regulation of death receptor-mediated apoptosis|down-regulation of extrinsic apoptotic signaling pathway via death domain receptors|downregulation of death receptor-mediated apoptosis|downregulation of extrinsic apoptotic signaling pathway via death domain receptors|negative regulation of death receptor-mediated apoptosis|down-regulation of death receptor-mediated apoptosis Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors. GO:0015912 short-chain fatty acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015912 The directed movement of short-chain fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Short-chain fatty acids are fatty acids with a chain length of less than C6. CHEBI:37258 2-hydroxyphytanic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37258 GO:1902040 positive regulation of seed dormancy process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902040 upregulation of seed dormancy|up-regulation of seed dormancy process|up regulation of seed dormancy|upregulation of seed dormancy process|positive regulation of seed dormancy|activation of seed dormancy|up regulation of seed dormancy process|up-regulation of seed dormancy|activation of seed dormancy process Any process that activates or increases the frequency, rate or extent of seed dormancy process. CHEBI:37251 3-oxopalmitic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37251 GO:0050282 serine 2-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050282 MetaCyc:SERINE-DEHYDROGENASE-RXN|RHEA:20884|EC:1.4.1.7 L-serine:NAD oxidoreductase (deaminating) activity|serine dehydrogenase activity|L-serine:NAD+ 2-oxidoreductase (deaminating) Catalysis of the reaction: L-serine + H2O + NAD+ = 3-hydroxypyruvate + NH3 + NADH. GO:0050283 serine-sulfate ammonia-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050283 MetaCyc:SERINE-SULFATE-AMMONIA-LYASE-RXN|RHEA:15605|EC:4.3.1.10 (L-SOS)lyase activity|serine-sulphate ammonia-lyase activity|L-serine-O-sulfate ammonia-lyase (pyruvate-forming) Catalysis of the reaction: L-serine O-sulfate + H2O = pyruvate + NH3 + sulfate. CHEBI:37252 (E)-hexadec-2-enoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37252 GO:0050280 sequoyitol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050280 EC:1.1.1.143|MetaCyc:SEQUOYITOL-DEHYDROGENASE-RXN|RHEA:11300|KEGG_REACTION:R03497 5-O-methyl-myo-inositol:NAD+ oxidoreductase activity Catalysis of the reaction: 1D-5-O-methyl-myo-inositol + NAD(+) = 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + H(+) + NADH. GO:0050281 serine-glyoxylate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050281 RHEA:19125|MetaCyc:SERINE--GLYOXYLATE-AMINOTRANSFERASE-RXN|EC:2.6.1.45 L-serine:glyoxylate aminotransferase activity|serine--glyoxylate aminotransferase activity|SGAT activity Catalysis of the reaction: L-serine + glyoxylate = 3-hydroxypyruvate + glycine. CHEBI:37250 (S)-3-hydroxypalmitic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37250 GO:0050286 sorbitol-6-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050286 RHEA:24580|KEGG_REACTION:R02866|EC:3.1.3.50|MetaCyc:SORBITOL-6-PHOSPHATASE-RXN sorbitol-6-phosphate phosphohydrolase activity|sorbitol-6-phosphate phosphatase activity Catalysis of the reaction: D-glucitol 6-phosphate + H(2)O = D-glucitol + phosphate. GO:0050287 sorbose 5-dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050287 RHEA:15001|EC:1.1.1.123|KEGG_REACTION:R01694|MetaCyc:SORBOSE-5-DEHYDROGENASE-NADP+-RXN sorbose (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity|L-sorbose:NADP+ 5-oxidoreductase activity|5-keto-D-fructose reductase activity|5-ketofructose reductase activity|reduced nicotinamide adenine dinucleotide phosphate-linked reductase activity Catalysis of the reaction: L-sorbose + NADP(+) = 5-dehydro-D-fructose + H(+) + NADPH. GO:0050284 sinapate 1-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050284 EC:2.4.1.120|RHEA:13305|MetaCyc:SINAPATE-1-GLUCOSYLTRANSFERASE-RXN UDP-glucose:sinapate D-glucosyltransferase activity|uridine 5'-diphosphoglucose-hydroxycinnamic acid acylglucosyltransferase activity|uridine diphosphoglucose-sinapate glucosyltransferase activity|UDPglucose:sinapic acid glucosyltransferase activity|UDPglucose:sinapate D-glucosyltransferase activity Catalysis of the reaction: UDP-glucose + sinapate = UDP + 1-sinapoyl-D-glucose. CHEBI:37253 elemental zinc biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37253 GO:0050285 sinapine esterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050285 KEGG_REACTION:R02381|MetaCyc:SINAPINE-ESTERASE-RXN|EC:3.1.1.49|RHEA:10016 aromatic choline esterase activity|sinapoylcholine sinapohydrolase activity Catalysis of the reaction: O-sinapoylcholine + H(2)O = choline + H(+) + sinapate. GO:0050299 streptomycin 3''-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050299 KEGG_REACTION:R02227|MetaCyc:STREPTOMYCIN-3-KINASE-RXN|EC:2.7.1.87|RHEA:18377 streptomycin 3''-phosphotransferase activity|ATP:streptomycin 3''-phosphotransferase activity|streptomycin 3''-kinase (phosphorylating) Catalysis of the reaction: ATP + streptomycin = ADP + 2 H(+) + streptomycin 3''-phosphate. CHEBI:37270 3-oxotetradecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37270 GO:0015928 fucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015928 Catalysis of the hydrolysis of fucosyl compounds, substances containing a group derived from a cyclic form of fucose or a fucose derivative. GO:0015929 hexosaminidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015929 MetaCyc:3.2.1.52-RXN Catalysis of the cleavage of hexosamine or N-acetylhexosamine residues (e.g. N-acetylglucosamine) residues from gangliosides or other glycoside oligosaccharides. GO:1902049 neosartoricin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902049 neosartoricin breakdown|neosartoricin catabolism|neosartoricin degradation The chemical reactions and pathways resulting in the breakdown of neosartoricin. GO:1902047 polyamine transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902047 polyamine import|polyamine uptake The process in which a polyamine macromolecule is transported across a membrane. GO:0015924 mannosyl-oligosaccharide mannosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015924 EC:3.2.1.- Catalysis of the hydrolysis of the terminal alpha-D-mannose residues in oligo-mannose oligosaccharides. GO:0015925 galactosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015925 Catalysis of the hydrolysis of galactosyl compounds, substances containing a group derived from a cyclic form of galactose or a galactose derivative. GO:1902048 neosartoricin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902048 neosartoricin metabolism The chemical reactions and pathways involving neosartoricin. GO:1902045 negative regulation of Fas signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902045 inhibition of FasR signaling pathway|down regulation of Fas signaling pathway|negative regulation of Apo-1 signaling pathway|down-regulation of Apo-1 signaling pathway|downregulation of FasL signaling pathway|downregulation of Fas signaling pathway|downregulation of Fas-FasL signaling pathway|negative regulation of FAS ligand-Fas signaling pathway|down-regulation of FAS ligand-Fas signaling pathway|negative regulation of Fas receptor signaling pathway|down-regulation of Fas receptor signaling pathway|down regulation of FasL signaling pathway|inhibition of Apo-1 signaling pathway|down regulation of Fas-FasL signaling pathway|down-regulation of CD95 signaling pathway|negative regulation of CD95 signaling pathway|downregulation of FAS ligand-Fas signaling pathway|down-regulation of Fas signaling pathway|downregulation of Fas receptor signaling pathway|inhibition of FasL signaling pathway|down-regulation of FasR signaling pathway|inhibition of Fas-FasL signaling pathway|negative regulation of FasR signaling pathway|down regulation of FAS ligand-Fas signaling pathway|down regulation of Fas receptor signaling pathway|inhibition of Fas signaling pathway|down regulation of Apo-1 signaling pathway|inhibition of Fas receptor signaling pathway|downregulation of CD95 signaling pathway|inhibition of FAS ligand-Fas signaling pathway|downregulation of FasR signaling pathway|downregulation of Apo-1 signaling pathway|down regulation of CD95 signaling pathway|negative regulation of FasL signaling pathway|down-regulation of FasL signaling pathway|inhibition of CD95 signaling pathway|down-regulation of Fas-FasL signaling pathway|negative regulation of Fas-FasL signaling pathway|down regulation of FasR signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of Fas signaling pathway. GO:0015926 glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015926 Catalysis of the hydrolysis of glucosyl compounds, substances containing a group derived from a cyclic form of glucose or a glucose derivative. GO:1902046 positive regulation of Fas signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902046 positive regulation of Apo-1 signaling pathway|upregulation of Fas signaling pathway|positive regulation of FasL signaling pathway|activation of Fas receptor signaling pathway|positive regulation of Fas-FasL signaling pathway|up-regulation of Fas receptor signaling pathway|upregulation of FasR signaling pathway|up regulation of FasL signaling pathway|up regulation of Fas-FasL signaling pathway|activation of FAS ligand-Fas signaling pathway|activation of CD95 signaling pathway|up-regulation of CD95 signaling pathway|positive regulation of FAS ligand-Fas signaling pathway|up regulation of Fas signaling pathway|activation of Fas signaling pathway|activation of FasR signaling pathway|up-regulation of Apo-1 signaling pathway|up-regulation of FasR signaling pathway|up regulation of FAS ligand-Fas signaling pathway|positive regulation of Fas receptor signaling pathway|upregulation of Fas-FasL signaling pathway|upregulation of FasL signaling pathway|up regulation of Fas receptor signaling pathway|positive regulation of CD95 signaling pathway|upregulation of Apo-1 signaling pathway|up regulation of CD95 signaling pathway|upregulation of FAS ligand-Fas signaling pathway|up-regulation of Fas-FasL signaling pathway|positive regulation of FasR signaling pathway|up-regulation of FasL signaling pathway|up-regulation of Fas signaling pathway|up regulation of FasR signaling pathway|upregulation of Fas receptor signaling pathway|activation of Fas-FasL signaling pathway|activation of FasL signaling pathway|up regulation of Apo-1 signaling pathway|upregulation of CD95 signaling pathway|up-regulation of FAS ligand-Fas signaling pathway|activation of Apo-1 signaling pathway Any process that activates or increases the frequency, rate or extent of Fas signaling pathway. GO:0015927 trehalase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015927 MetaCyc:TREHALA-RXN|RHEA:32675 Catalysis of the hydrolysis of trehalose or a trehalose derivative. GO:1902054 negative regulation of neosartoricin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902054 inhibition of neosartoricin anabolism|downregulation of neosartoricin biosynthesis|downregulation of neosartoricin biosynthetic process|inhibition of neosartoricin synthesis|down regulation of neosartoricin biosynthesis|down regulation of neosartoricin biosynthetic process|down regulation of neosartoricin anabolism|inhibition of neosartoricin biosynthetic process|inhibition of neosartoricin formation|down regulation of neosartoricin synthesis|downregulation of neosartoricin anabolism|inhibition of neosartoricin biosynthesis|down regulation of neosartoricin formation|downregulation of neosartoricin synthesis|downregulation of neosartoricin formation|down-regulation of neosartoricin anabolism|negative regulation of neosartoricin anabolism|down-regulation of neosartoricin biosynthetic process|negative regulation of neosartoricin biosynthesis|down-regulation of neosartoricin biosynthesis|down-regulation of neosartoricin synthesis|negative regulation of neosartoricin synthesis|down-regulation of neosartoricin formation|negative regulation of neosartoricin formation Any process that stops, prevents or reduces the frequency, rate or extent of neosartoricin biosynthetic process. GO:0015920 lipopolysaccharide transport biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0015920 LPS transport The directed movement of lipopolysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide. GO:1902055 positive regulation of neosartoricin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902055 up regulation of neosartoricin biosynthesis|up regulation of neosartoricin biosynthetic process|up-regulation of neosartoricin synthesis|up-regulation of neosartoricin formation|upregulation of neosartoricin anabolism|upregulation of neosartoricin synthesis|upregulation of neosartoricin biosynthesis|upregulation of neosartoricin biosynthetic process|upregulation of neosartoricin formation|up regulation of neosartoricin anabolism|positive regulation of neosartoricin anabolism|up-regulation of neosartoricin biosynthetic process|up-regulation of neosartoricin biosynthesis|up regulation of neosartoricin synthesis|activation of neosartoricin biosynthetic process|positive regulation of neosartoricin synthesis|activation of neosartoricin anabolism|up regulation of neosartoricin formation|positive regulation of neosartoricin formation|activation of neosartoricin biosynthesis|activation of neosartoricin synthesis|up-regulation of neosartoricin anabolism|activation of neosartoricin formation|positive regulation of neosartoricin biosynthesis Any process that activates or increases the frequency, rate or extent of neosartoricin biosynthetic process. GO:0015921 lipopolysaccharide export biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015921 LPS export The directed movement of lipopolysaccharides out of a cell or organelle. GO:1902052 (25S)-Delta(7)-dafachronate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1902052 Interacting selectively and non-covalently with (25S)-Delta(7)-dafachronate. GO:0015922 aspartate oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015922 Catalysis of the reaction: aspartate + O2 = iminosuccinate + hydrogen peroxide. GO:1902053 regulation of neosartoricin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902053 regulation of neosartoricin biosynthesis|regulation of neosartoricin anabolism|regulation of neosartoricin synthesis|regulation of neosartoricin formation Any process that modulates the frequency, rate or extent of neosartoricin biosynthetic process. GO:0015923 mannosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015923 Catalysis of the hydrolysis of mannosyl compounds, substances containing a group derived from a cyclic form of mannose or a mannose derivative. GO:1902050 neosartoricin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902050 neosartoricin biosynthesis|neosartoricin anabolism|neosartoricin synthesis|neosartoricin formation The chemical reactions and pathways resulting in the formation of neosartoricin. GO:0050290 sphingomyelin phosphodiesterase D activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050290 RHEA:20984|KEGG_REACTION:R02542|EC:3.1.4.41|MetaCyc:SPHINGOMYELIN-PHOSPHODIESTERASE-D-RXN sphingomyelinase D|sphingomyelin ceramide-phosphohydrolase activity Catalysis of the reaction: H(2)O + sphingomyelin = ceramide 1-phosphate + choline + H(+). GO:1902051 (25S)-Delta(4)-dafachronate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1902051 Interacting selectively and non-covalently with (25S)-Delta(4)-dafachronate. GO:0050293 steroid-lactonase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050293 RHEA:13721|KEGG_REACTION:R03641|MetaCyc:STEROID-LACTONASE-RXN|EC:3.1.1.37 testololactone lactonohydrolase activity Catalysis of the reaction: H(2)O + testololactone = H(+) + testolate. GO:0050294 steroid sulfotransferase activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0050294 MetaCyc:STEROID-SULFOTRANSFERASE-RXN|EC:2.8.2.15|Reactome:R-HSA-176521|Reactome:R-HSA-176517|Reactome:R-HSA-176631 steroid alcohol sulfotransferase|3'-phosphoadenylyl-sulfate:phenolic-steroid sulfotransferase activity|steroid sulphotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a phenolic steroid = adenosine 3',5'-bisphosphate + steroid O-sulfate. GO:0050291 sphingosine N-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050291 EC:2.3.1.24|RHEA:23768|Reactome:R-HSA-428185|MetaCyc:SPHINGOSINE-N-ACYLTRANSFERASE-RXN sphingosine acyltransferase activity|dihydroceramide synthase activity|ceramide synthetase activity|acyl-CoA:sphingosine N-acyltransferase activity|ceramide synthase activity Catalysis of the reaction: acyl-CoA + sphingosine = CoA + N-acylsphingosine. CHEBI:37260 hept-2-enedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37260 GO:0050292 steroid 9-alpha-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050292 RHEA:19557|MetaCyc:STEROID-9-ALPHA-MONOOXYGENASE-RXN|KEGG_REACTION:R04392|EC:1.14.99.24 steroid,hydrogen-donor:oxygen oxidoreductase (9-epoxidizing)|steroid 9alpha-monooxygenase activity|steroid 9-alpha-hydroxylase activity|steroid 9alpha-hydroxylase activity|steroid 9a-monooxygenase activity Catalysis of the reaction: AH(2) + O(2) + pregna-4,9(11)-diene-3,20-dione = 9,11alpha-epoxypregn-4-ene-3,20-dione + A + H(2)O. GO:0050297 stizolobate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050297 RHEA:21220|EC:1.13.11.29|MetaCyc:STIZOLOBATE-SYNTHASE-RXN 3,4-dihydroxy-L-phenylalanine:oxygen 4,5-oxidoreductase (recyclizing) Catalysis of the reaction: 3,4-dihydroxy-L-phenylalanine + O2 = 4-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde. GO:0050298 stizolobinate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050298 MetaCyc:STIZOLOBINATE-SYNTHASE-RXN|RHEA:18465|EC:1.13.11.30 3,4-dihydroxy-L-phenylalanine:oxygen 2,3-oxidoreductase (recyclizing) Catalysis of the reaction: 3,4-dihydroxy-L-phenylalanine + O2 = 5-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde. GO:0050295 steryl-beta-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050295 RHEA:11956|KEGG_REACTION:R01460|EC:3.2.1.104|MetaCyc:STERYL-BETA-GLUCOSIDASE-RXN cholesteryl-beta-D-glucoside glucohydrolase activity|steryl-b-glucosidase activity Catalysis of the reaction: cholesteryl-beta-D-glucoside + H(2)O = D-glucose + cholesterol. GO:0050296 stipitatonate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050296 KEGG_REACTION:R03739|MetaCyc:STIPITATONATE-DECARBOXYLASE-RXN|RHEA:13885|EC:4.1.1.60 stipitatonate carboxy-lyase (decyclizing)|stipitatonate carboxy-lyase (decyclizing, stipitatate-forming) Catalysis of the reaction: H(2)O + stipitatonate = CO(2) + H(+) + stipitatate. GO:1902058 regulation of sporocarp development involved in sexual reproduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902058 regulation of ascus development|regulation of fruiting body formation involved in sexual reproduction|regulation of perfect stage fruiting body development|regulation of fruiting body development involved in sexual reproduction Any process that modulates the frequency, rate or extent of sporocarp development involved in sexual reproduction. GO:1902059 negative regulation of sporocarp development involved in sexual reproduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902059 downregulation of ascus development|down regulation of fruiting body formation involved in sexual reproduction|down-regulation of sporocarp development involved in sexual reproduction|negative regulation of fruiting body development involved in sexual reproduction|down-regulation of fruiting body development involved in sexual reproduction|downregulation of fruiting body formation involved in sexual reproduction|inhibition of perfect stage fruiting body development|down-regulation of ascus development|negative regulation of ascus development|inhibition of sporocarp development involved in sexual reproduction|down regulation of perfect stage fruiting body development|down-regulation of fruiting body formation involved in sexual reproduction|negative regulation of fruiting body formation involved in sexual reproduction|inhibition of fruiting body development involved in sexual reproduction|downregulation of perfect stage fruiting body development|down regulation of sporocarp development involved in sexual reproduction|inhibition of ascus development|down regulation of fruiting body development involved in sexual reproduction|down-regulation of perfect stage fruiting body development|negative regulation of perfect stage fruiting body development|downregulation of sporocarp development involved in sexual reproduction|inhibition of fruiting body formation involved in sexual reproduction|downregulation of fruiting body development involved in sexual reproduction|down regulation of ascus development Any process that stops, prevents or reduces the frequency, rate or extent of sporocarp development involved in sexual reproduction. UBERON:0010221 laryngeal associated mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010221 GO:1902056 (25S)-Delta(7)-dafachronate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902056 (25S)-Delta(7)-dafachronate metabolism The chemical reactions and pathways involving (25S)-Delta(7)-dafachronate. GO:1902057 (25S)-Delta(4)-dafachronate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902057 (25S)-Delta(4)-dafachronate metabolism The chemical reactions and pathways involving (25S)-Delta(4)-dafachronate. GO:1902065 response to L-glutamate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902065 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-glutamate stimulus. CHEBI:37237 elemental molybdenum biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37237 GO:1902066 regulation of cell wall pectin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902066 regulation of cellulose and pectin-containing cell wall pectin metabolic process|regulation of pectin metabolism during cell wall biogenesis|regulation of plant-type cell wall pectin metabolic process|regulation of cell wall pectin metabolism Any process that modulates the frequency, rate or extent of cell wall pectin metabolic process. GO:1902063 betaine aldehyde biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902063 betaine aldehyde anabolism|betaine aldehyde synthesis|betaine aldehyde formation|betaine aldehyde biosynthesis The chemical reactions and pathways resulting in the formation of betaine aldehyde. GO:1902064 regulation of transcription from RNA polymerase II promoter involved in spermatogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902064 regulation of global transcription from Pol II promoter involved in spermatogenesis|regulation of transcription from RNA polymerase II promoter, global involved in generation of spermatozoa|regulation of transcription from RNA polymerase II promoter, global involved in spermatogenesis|global transcription regulation from Pol II promoter involved in generation of spermatozoa|global transcription regulation from Pol II promoter involved in spermatogenesis|regulation of gene-specific transcription from RNA polymerase II promoter involved in generation of spermatozoa|regulation of transcription from Pol II promoter involved in generation of spermatozoa|regulation of gene-specific transcription from RNA polymerase II promoter involved in spermatogenesis|regulation of transcription from RNA polymerase II promoter involved in generation of spermatozoa|regulation of transcription from Pol II promoter involved in spermatogenesis|regulation of global transcription from Pol II promoter involved in generation of spermatozoa Any regulation of transcription from RNA polymerase II promoter that is involved in spermatogenesis. GO:1902061 betaine aldehyde metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902061 betaine aldehyde metabolism The chemical reactions and pathways involving betaine aldehyde. GO:1902062 betaine aldehyde catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902062 betaine aldehyde catabolism|betaine aldehyde degradation|betaine aldehyde breakdown The chemical reactions and pathways resulting in the breakdown of betaine aldehyde. CHEBI:37239 molybdenum cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37239 GO:1902060 positive regulation of sporocarp development involved in sexual reproduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902060 up regulation of perfect stage fruiting body development|upregulation of fruiting body development involved in sexual reproduction|positive regulation of perfect stage fruiting body development|up-regulation of fruiting body formation involved in sexual reproduction|upregulation of ascus development|activation of perfect stage fruiting body development|up regulation of sporocarp development involved in sexual reproduction|activation of sporocarp development involved in sexual reproduction|up regulation of fruiting body development involved in sexual reproduction|upregulation of fruiting body formation involved in sexual reproduction|positive regulation of fruiting body development involved in sexual reproduction|up-regulation of perfect stage fruiting body development|up regulation of ascus development|activation of fruiting body development involved in sexual reproduction|positive regulation of ascus development|up regulation of fruiting body formation involved in sexual reproduction|up-regulation of sporocarp development involved in sexual reproduction|upregulation of perfect stage fruiting body development|positive regulation of fruiting body formation involved in sexual reproduction|activation of ascus development|up-regulation of fruiting body development involved in sexual reproduction|activation of fruiting body formation involved in sexual reproduction|up-regulation of ascus development|upregulation of sporocarp development involved in sexual reproduction Any process that activates or increases the frequency, rate or extent of sporocarp development involved in sexual reproduction. GO:0015906 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015906 GO:0015907 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015907 GO:0015908 fatty acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015908 The directed movement of fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis. GO:0015909 long-chain fatty acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015909 The directed movement of long-chain fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22. GO:0015902 carbonyl cyanide m-chlorophenylhydrazone transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015902 CCCP transport The directed movement of carbonyl cyanide m-chlorophenylhydrazone into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbonyl cyanide m-chlorophenylhydrazone is a proton ionophore, commonly used as an uncoupling agent and inhibitor of photosynthesis because of its effects on mitochondrial and chloroplast membranes. GO:1902069 negative regulation of sphingolipid mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902069 downregulation of sphingolipid signaling pathway|downregulation of sphingolipid mediated signaling pathway|down regulation of sphingolipid signaling pathway|down-regulation of sphingolipid mediated signaling pathway|inhibition of sphingolipid signaling pathway|inhibition of sphingolipid mediated signaling pathway|down-regulation of sphingolipid signaling pathway|negative regulation of sphingolipid signaling pathway|down regulation of sphingolipid mediated signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of sphingolipid signaling. UBERON:0010212 laryngeal apparatus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010212 laryngeal cartilage system Apparatus located between the lungs and the buccal cavity. This apparatus is composed of a pair of arytenoid cartilages that are supported by the cricoid ring. GO:0015903 fluconazole transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015903 The directed movement of fluconazole into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fluconazole is an antifungal drug used for oral candidiasis and cryptococcal meningitis; it is still under study for treatment of vaginal candidiasis and other fungal infections. UBERON:0010213 laryngeal pre-cartilage condensation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010213 UBERON:0010210 blood clot biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010210 coagulated blood|clot|thrombus|hemostatic plug|fibrin clot A semisolid gelatinous mass of coagulated blood that consists of red blood cells, white blood cells, and platelets entrapped in a fibrin network. GO:1902067 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902067 GO:0015904 tetracycline transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015904 tetracyclin transport|tetracycline transport The directed movement of tetracycline from one side of a membrane to the other. Tetracycline is a broad spectrum antibiotic that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles). GO:1902068 regulation of sphingolipid mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902068 regulation of sphingolipid signaling pathway Any process that modulates the frequency, rate or extent of sphingolipid signaling. GO:0015905 bicyclomycin transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015905 bicyclomycin transport The directed movement of bicyclomycin across a lipid bilayer, from one side of a membrane to the other. Bicyclomycin (or bicozamycin) is an antibacterial drug often used as a livestock feed additive. CHEBI:37248 3-hydroxypalmitic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37248 GO:1902076 regulation of lateral motor column neuron migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902076 Any process that modulates the frequency, rate or extent of lateral motor column neuron migration. GO:1902077 negative regulation of lateral motor column neuron migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902077 down-regulation of lateral motor column neuron migration|inhibition of lateral motor column neuron migration|down regulation of lateral motor column neuron migration|downregulation of lateral motor column neuron migration Any process that stops, prevents or reduces the frequency, rate or extent of lateral motor column neuron migration. GO:1902074 response to salt biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902074 response to salinity Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus. GO:0015900 benomyl transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015900 The directed movement of benomyl into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Benomyl, methyl 1-(butylcarbamoyl)-2-benzimidazolecarbamate, is a systemic agricultural fungicide used for control of certain fungal diseases of stone fruit. CHEBI:37246 elemental sodium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37246 GO:0015901 cycloheximide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015901 The directed movement of cycloheximide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Cycloheximide is an antibiotic produced by Streptomyces which interferes with protein synthesis in eukaryotes. GO:1902075 cellular response to salt biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902075 cellular response to salinity Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus. UBERON:0010204 tail vasculature biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010204 post-vent vasculature|tail vasculature A vasculature that is part of a post-anal tail. CHEBI:37247 elemental potassium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37247 GO:1902072 negative regulation of hypoxia-inducible factor-1alpha signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902072 inhibition of hypoxia-inducible factor-1alpha signalling pathway|inhibition of HIF1alpha pathway|down regulation of hypoxia-inducible factor-1alpha signaling pathway|downregulation of hypoxia-inducible factor-1alpha signaling pathway|down regulation of HIF1alpha pathway|negative regulation of hypoxia-inducible factor-1alpha signalling pathway|down-regulation of hypoxia-inducible factor-1alpha signalling pathway|downregulation of HIF1alpha pathway|down-regulation of hypoxia-inducible factor-1alpha signaling pathway|downregulation of hypoxia-inducible factor-1alpha signalling pathway|negative regulation of HIF1alpha pathway|down-regulation of HIF1alpha pathway|inhibition of hypoxia-inducible factor-1alpha signaling pathway|down regulation of hypoxia-inducible factor-1alpha signalling pathway Any process that stops, prevents or reduces the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway. GO:1902073 positive regulation of hypoxia-inducible factor-1alpha signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902073 up-regulation of HIF1alpha pathway|upregulation of hypoxia-inducible factor-1alpha signaling pathway|up-regulation of hypoxia-inducible factor-1alpha signalling pathway|upregulation of HIF1alpha pathway|activation of hypoxia-inducible factor-1alpha signalling pathway|up regulation of hypoxia-inducible factor-1alpha signaling pathway|activation of hypoxia-inducible factor-1alpha signaling pathway|positive regulation of hypoxia-inducible factor-1alpha signalling pathway|up regulation of HIF1alpha pathway|up regulation of hypoxia-inducible factor-1alpha signalling pathway|positive regulation of HIF1alpha pathway|hypoxic stabilization of HIF1A|activation of HIF1alpha pathway|up-regulation of hypoxia-inducible factor-1alpha signaling pathway|upregulation of hypoxia-inducible factor-1alpha signalling pathway Any process that activates or increases the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway. GO:1902070 positive regulation of sphingolipid mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902070 activation of sphingolipid signaling pathway|upregulation of sphingolipid mediated signaling pathway|positive regulation of sphingolipid signaling pathway|up regulation of sphingolipid signaling pathway|up regulation of sphingolipid mediated signaling pathway|activation of sphingolipid mediated signaling pathway|upregulation of sphingolipid signaling pathway|up-regulation of sphingolipid signaling pathway|up-regulation of sphingolipid mediated signaling pathway Any process that activates or increases the frequency, rate or extent of sphingolipid signaling. UBERON:0010207 nictitating membrane biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010207 membrana nictitans|palperbra tertia|haw|nictitans|third eyelid A fold of the mucous membrane of the conjunctiva in many animals. At rest, it is hidden in the medial canthus. It can extend to cover part or all of the cornea to help clean the cornea. GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902071 regulation of HIF1alpha pathway|regulation of hypoxia-inducible factor-1alpha signalling pathway Any process that modulates the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway. CHEBI:37240 adenosine 3',5'-bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37240 CHEBI:13253 Asp-tRNA(Asx) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_13253 CHEBI:37245 (E)-3-methylglutaconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37245 CHEBI:52857 S-sulfanylglutathione biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52857 CHEBI:52859 choline hydrogen sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52859 CHEBI:27897 tryptophan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27897 CHEBI:27898 cyanidin 3-O-(6-O-glucosyl-2-O-xylosylgalactoside) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27898 CHEBI:27899 cisplatin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27899 CHEBI:27895 2-chloro-cis,cis-muconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27895 UBERON:0010202 lateral line biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010202 lateral lines The lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line develops from cranial ectodermal placodes situated behind the ear and between the eye and ear. GO:1902078 positive regulation of lateral motor column neuron migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902078 up-regulation of lateral motor column neuron migration|upregulation of lateral motor column neuron migration|up regulation of lateral motor column neuron migration|activation of lateral motor column neuron migration Any process that activates or increases the frequency, rate or extent of lateral motor column neuron migration. GO:1902079 D-valine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902079 D-valine degradation|D-valine breakdown|D-valine catabolism The chemical reactions and pathways resulting in the breakdown of D-valine. CHEBI:27891 S-sulfo-L-cysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27891 GO:1902087 dimethylsulfoniopropionate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902087 S,S-dimethyl-beta-propiothetin catabolic process|S,S-dimethyl-beta-propiothetin degradation|S,S-dimethyl-beta-propiothetin breakdown|S,S-dimethyl-beta-propiothetin catabolism The chemical reactions and pathways resulting in the breakdown of S,S-dimethyl-beta-propiothetin. GO:1902088 plant-type cell wall loosening involved in abscission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902088 cellulose and pectin-containing cell wall loosening involved in abscission Any plant-type cell wall loosening that is involved in abscission. GO:1902085 fumagillin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902085 fumagillin catabolism|fumagillin degradation|fumagillin breakdown The chemical reactions and pathways resulting in the breakdown of fumagillin. GO:1902086 fumagillin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902086 fumagillin anabolism|fumagillin biosynthesis|fumagillin synthesis|fumagillin formation The chemical reactions and pathways resulting in the formation of fumagillin. GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902083 down-regulation of peptidyl-cysteine S-nitrosylation|inhibition of protein S-nitrosylation|inhibition of S-nitrosylation|inhibition of peptidyl-cysteine S-nitrosylation|down regulation of protein S-nitrosylation|down regulation of S-nitrosylation|downregulation of protein S-nitrosylation|downregulation of S-nitrosylation|down regulation of peptidyl-cysteine S-nitrosylation|negative regulation of protein S-nitrosylation|down-regulation of protein S-nitrosylation|downregulation of peptidyl-cysteine S-nitrosylation|down-regulation of S-nitrosylation|negative regulation of S-nitrosylation Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-cysteine S-nitrosylation. GO:1902084 fumagillin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902084 fumagillin metabolism The chemical reactions and pathways involving fumagillin. GO:1902081 negative regulation of calcium ion import into sarcoplasmic reticulum biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902081 down-regulation of calcium ion import into sarcoplasmic reticulum|downregulation of calcium ion import into sarcoplasmic reticulum|down regulation of calcium ion import into sarcoplasmic reticulum|inhibition of calcium ion import into sarcoplasmic reticulum Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum. GO:1902082 positive regulation of calcium ion import into sarcoplasmic reticulum biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902082 up regulation of calcium ion import into sarcoplasmic reticulum|upregulation of calcium ion import into sarcoplasmic reticulum|up-regulation of calcium ion import into sarcoplasmic reticulum|activation of calcium ion import into sarcoplasmic reticulum Any process that activates or increases the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum. GO:1902080 regulation of calcium ion import into sarcoplasmic reticulum biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902080 Any process that modulates the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum. UBERON:0009210 pharyngeal membrane biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009210 pharyngeal membrane|branchial membrane|branchial arch membrane A thin fold of ectoderm and endoderm that separates the pharyngeal pouches from the pharyngeal clefts in a developing embryo. UBERON:0009213 pharyngeal membrane of 1st arch biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009213 future tympanic membrane|tympanic membrane primordium|1st pharyngeal membrane|1st branchial membrane A pharyngeal membrane that separates the first pharyngeal cleft from the first pharyngeal pouch. CHEBI:52845 cyclic organic group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52845 GO:1902089 cell wall polysaccharide catabolic process involved in lateral root development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902089 cell wall polysaccharide breakdown involved in lateral root development Any cell wall polysaccharide catabolic process that is involved in lateral root development. GO:1902098 calcitriol binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1902098 hormonally active vitamin D3 binding|1,25-dihydroxycholecalciferol binding|1,25-dihydroxyvitamin D3 binding|1alpha,25-dihydroxyvitamin D3 binding|1alpha,25-dihydroxycholecalciferol binding|1alpha,25(OH)2D3 binding|1alpha,25(OH)2 vitamin D3 binding Interacting selectively and non-covalently with calcitriol. Calcitriol (1,25-dihydroxycholecalciferol) is the hormonally active form of vitamin D3. UBERON:0009205 lateral nasal process mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009205 mesenchyme of latero-nasal process Mesenchyme that is part of a lateral nasal prominence. GO:1902099 regulation of metaphase/anaphase transition of cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902099 Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of cell cycle. UBERON:0009206 lateral nasal process surface ectoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009206 ectoderm of latero-nasal process An ectoderm that is part of a lateral nasal prominence. GO:1902096 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902096 GO:1902097 positive regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902097 up-regulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|upregulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|positive regulation of global transcription from Pol II promoter involved in defense response to Gram-negative bacteria|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|positive regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|upregulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|positive regulation of transcription from Pol II promoter involved in defence response to Gram-negative bacteria|activation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|up regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|upregulation of global transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|upregulation of transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|stimulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|activation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|up-regulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|upregulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|activation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|up-regulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|stimulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|positive regulation of global transcription from Pol II promoter involved in defence response to Gram-negative bacterium|up-regulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|stimulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|positive regulation of transcription from Pol II promoter involved in Gram-negative antibacterial peptide activity|stimulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|up regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|up regulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|positive regulation of transcription from Pol II promoter involved in defence response to Gram-negative bacterium|activation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|up regulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|up regulation of global transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|upregulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|up-regulation of transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|up-regulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|positive regulation of global transcription from Pol II promoter involved in defence response to Gram-negative bacteria|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|upregulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|stimulation of transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|positive regulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|upregulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|positive regulation of global transcription from Pol II promoter involved in Gram-negative antibacterial peptide activity|activation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|positive regulation of transcription from Pol II promoter involved in defense response to Gram-negative bacteria|up regulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|activation of transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|stimulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|activation of global transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|activation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|activation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|upregulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|up-regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|stimulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|positive regulation of global transcription from Pol II promoter involved in defense response to Gram-negative bacterium|stimulation of global transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|up-regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|up-regulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|positive regulation of transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|stimulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|up regulation of transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|up regulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|up-regulation of global transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|stimulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|activation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|positive regulation of transcription from Pol II promoter involved in defense response to Gram-negative bacterium|up regulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|positive regulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|up regulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|upregulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria Any positive regulation of transcription from RNA polymerase II promoter that is involved in defense response to Gram-negative bacterium. GO:1902094 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902094 GO:1902095 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902095 GO:1902092 positive regulation of fumagillin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902092 upregulation of fumagillin anabolism|upregulation of fumagillin synthesis|up regulation of fumagillin biosynthesis|up regulation of fumagillin biosynthetic process|upregulation of fumagillin formation|activation of fumagillin biosynthetic process|positive regulation of fumagillin biosynthesis|up-regulation of fumagillin anabolism|activation of fumagillin biosynthesis|up-regulation of fumagillin synthesis|activation of fumagillin anabolism|up-regulation of fumagillin formation|up-regulation of fumagillin biosynthetic process|activation of fumagillin synthesis|up-regulation of fumagillin biosynthesis|positive regulation of fumagillin anabolism|up regulation of fumagillin anabolism|activation of fumagillin formation|positive regulation of fumagillin synthesis|up regulation of fumagillin synthesis|positive regulation of fumagillin formation|upregulation of fumagillin biosynthetic process|upregulation of fumagillin biosynthesis|up regulation of fumagillin formation Any process that activates or increases the frequency, rate or extent of fumagillin biosynthetic process. GO:1902093 positive regulation of flagellated sperm motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902093 up-regulation of sperm motility|upregulation of sperm movement|up-regulation of sperm movement|up regulation of sperm motility|activation of sperm movement|activation of sperm motility|positive regulation of sperm movement|upregulation of sperm motility|up regulation of sperm movement|positive regulation of sperm motility Any process that activates or increases the frequency, rate or extent of flagellated sperm motility. GO:1902090 regulation of fumagillin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902090 regulation of fumagillin synthesis|regulation of fumagillin biosynthesis|regulation of fumagillin formation|regulation of fumagillin anabolism Any process that modulates the frequency, rate or extent of fumagillin biosynthetic process. GO:1902091 negative regulation of fumagillin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902091 down regulation of fumagillin biosynthetic process|down regulation of fumagillin biosynthesis|downregulation of fumagillin formation|down regulation of fumagillin synthesis|downregulation of fumagillin biosynthetic process|downregulation of fumagillin biosynthesis|down regulation of fumagillin formation|inhibition of fumagillin anabolism|inhibition of fumagillin synthesis|inhibition of fumagillin formation|down-regulation of fumagillin biosynthesis|negative regulation of fumagillin biosynthesis|down-regulation of fumagillin biosynthetic process|negative regulation of fumagillin anabolism|down-regulation of fumagillin anabolism|inhibition of fumagillin biosynthetic process|negative regulation of fumagillin synthesis|down-regulation of fumagillin synthesis|negative regulation of fumagillin formation|down-regulation of fumagillin formation|inhibition of fumagillin biosynthesis|downregulation of fumagillin anabolism|downregulation of fumagillin synthesis|down regulation of fumagillin anabolism Any process that stops, prevents or reduces the frequency, rate or extent of fumagillin biosynthetic process. UBERON:0009200 limb epidermis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009200 The limb epidermis is the outer epithelial layer of the limb, it is a complex stratified squamous epithelium. UBERON:0009201 nephric duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009201 A nephric duct is a tube that drains a primitive kidney[GO]. UBERON:0009203 internasal suture biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009203 nasal suture|inter-nasal suture|internasal suture of skull|sutura internasalis|sutura internasalis A suture joining the nasal bones. UBERON:0009204 medial nasal process mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009204 Mesenchyme that is part of a medial nasal prominence. CL:0000127 astrocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000127 astrocytic glia A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from 'star' cells) are irregularly shaped with many long processes, including those with 'end feet' which form the glial (limiting) membrane and directly and indirectly contribute to the blood-brain barrier. They regulate the extracellular ionic and chemical environment, and 'reactive astrocytes' (along with microglia) respond to injury. CL:0000128 oligodendrocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000128 OLs|oligodendroglia A class of large neuroglial (macroglial) cells in the central nervous system. Form the insulating myelin sheath of axons in the central nervous system. CL:0000129 microglial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000129 brain macrophage|microgliocyte|brain-resident macrophage|hortega cells|MF.microglia.CNS|microglia A central nervous system macrophage found in the parenchyma of the central nervous system. Marker include CD11b-positive, F4/80-positive, and CD68-positive. GO:0015898 amiloride transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015898 The directed movement amiloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Amiloride is a potent and specific inhibitor of sodium ion entry into cells. It is used as a potassium-sparing diuretic. GO:0015899 aminotriazole transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015899 The directed movement of aminotriazole into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aminotriazole is an effective weed killer that also possesses some antithyroid activity. CL:0000120 granule cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000120 CL:0000121 Purkinje cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000121 Purkinje neuron|cerebellum Purkinje cell|cerebellar Purkinje cell|Purkinje's cell The output neuron of the cerebellar cortex. CL:0000122 stellate neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000122 GO:0015894 acriflavine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015894 acriflavin transport The directed movement of acriflavine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acriflavine is a fluorescent dye used as a local antiseptic and also as a biological stain. It intercalates into nucleic acids thereby inhibiting bacterial and viral replication. CL:0000123 neuron associated cell (sensu Vertebrata) biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000123 GO:0015895 alkane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015895 The directed movement of alkanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alkanes are saturated aliphatic hydrocarbon compounds. CL:0000125 glial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000125 neuroglia|neuroglial cell A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons. GO:0015896 nalidixic acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015896 The directed movement of nalidixic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Nalidixic acid is a synthetic antibiotic that interferes with DNA gyrase and inhibits prokaryotic replication. CL:0000126 macroglial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000126 macrogliocyte A neuroglial cell of ectodermal origin, i.e., the astrocytes and oligodendrocytes considered together. GO:0015897 organomercurial transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015897 The process in which an organomercurial compound is transported across a membrane. Organomercurial substances are any organic compound containing a mercury atom. GO:0015890 nicotinamide mononucleotide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015890 nicotinamide ribonucleotide transport The directed movement of nicotinamide mononucleotide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of D-ribose. It is a constituent of NAD and NADP. GO:0015891 siderophore transport biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0015891 siderophore-iron transport|iron-siderochrome transport|siderochrome transport|iron-siderophore transport The directed movement of siderophores, low molecular weight Fe(III)-chelating substances, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015892 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015892 GO:0015893 drug transport biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0015893 The directed movement of a drug, a substance used in the diagnosis, treatment or prevention of a disease, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:86160 (2E)-pentenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86160 CHEBI:86162 1-tetradecanoyl-2-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86162 CL:0000138 chondrocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000138 cartilage cell Skeletogenic cell that is terminally differentiated, secretes an avascular, GAG-rich matrix, is embedded in cartilage tissue matrix, retains the ability to divide, and develops from a chondroblast cell. CHEBI:86165 (24S,25S)-cholest-5-en-3beta,24,26-triol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86165 CL:0000133 neurectodermal cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000133 neurectoderm cell Ectoderm destined to be nervous tissue. CL:0000134 mesenchymal stem cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000134 BMSC|mesenchymal precursor cell|mesenchymal stem cell|mesenchymal stromal cell|MSC|stem cells, mesenchymal|colony-forming unit-fibroblast|mesenchymal progenitor cells|mesenchymal stromal cells|marrow stromal cells|bone marrow stromal cells|CFU-F A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. In humans, this cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs. CL:0000135 fibrocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000135 An inactive fibroblast; cytoplasm is sparse, endoplasmic reticulum is scanty with flattened nucleus. Term used by some histologists; when fibroblasts become relatively inactive in fiber formation. However, this cell has the potential for fibrogenesis in quiescent connective tissue of the adult, as well as during development, other histologists prefer to use the term fibroblast in all circumstances. These cells represent ~0.5% of peripheral blood leukocytes. CL:0000136 fat cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000136 adipocyte|adipose cell A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of triglycerides. GO:0050202 octopamine dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050202 MetaCyc:OCTOPAMINE-DEHYDRATASE-RXN|EC:4.2.1.87|KEGG_REACTION:R03358|RHEA:18173 octopamine hydro-lyase (deaminating)|octopamine hydrolyase activity|octopamine hydro-lyase [deaminating; (4-hydroxyphenyl)acetaldehyde-forming] Catalysis of the reaction: 1-(4-hydroxyphenyl)-2-aminoethanol = (4-hydroxyphenyl)acetaldehyde + NH(4)(+). GO:0050203 oxalate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050203 KEGG_REACTION:R01558|EC:6.2.1.8|MetaCyc:OXALATE--COA-LIGASE-RXN|RHEA:18293 oxalyl coenzyme A synthetase activity|oxalate:CoA ligase (AMP-forming)|oxalyl-CoA synthetase activity Catalysis of the reaction: ATP + CoA + oxalate = AMP + diphosphate + H(+) + oxalyl-CoA. GO:0050200 plasmalogen synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050200 EC:2.3.1.25|MetaCyc:PLASMALOGEN-SYNTHASE-RXN 1-alkenyl-glycero-3-phosphorylcholine:acyl-CoA acyltransferase activity|lysoplasmenylcholine acyltransferase activity|acyl-CoA:1-O-alk-1-enyl-glycero-3-phosphocholine 2-O-acyltransferase activity|O-1-alkenylglycero-3-phosphorylcholine acyltransferase activity Catalysis of the reaction: acyl-CoA + 1-O-alk-1-enyl-glycero-3-phosphocholine = CoA + plasmenylcholine. GO:0050201 fucokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050201 Reactome:R-HSA-6787540|MetaCyc:FUCOKINASE-RXN|EC:2.7.1.52|RHEA:13241|KEGG_REACTION:R03161 L-fucokinase activity|fucokinase (phosphorylating) activity|L-fucose kinase activity|fucose kinase activity|ATP:6-deoxy-L-galactose 1-phosphotransferase activity|ATP:beta-L-fucose 1-phosphotransferase activity Catalysis of the reaction: L-fucose + ATP = beta-L-fucose 1-phosphate + ADP + 2 H(+). GO:0050206 oximinotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050206 RHEA:11624|KEGG_REACTION:R03796|EC:2.6.3.1|MetaCyc:OXIMINOTRANSFERASE-RXN transoximase activity|oximase activity|transoximinase activity|pyruvate-acetone oximinotransferase activity|pyruvate-oxime:acetone oximinotransferase activity Catalysis of the reaction: 2-(hydroxyimino)propanoate + acetone = acetone oxime + pyruvate. GO:0050207 plasmanylethanolamine desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050207 RHEA:22956|EC:1.14.99.19|MetaCyc:PLASMANYLETHANOLAMINE-DESATURASE-RXN 1-O-alkyl 2-acyl-sn-glycero-3-phosphorylethanolamine desaturase activity|plasmenylethanolamine desaturase activity|O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine,hydrogen-donor:oxygen oxidoreductase activity|alkylacylglycero-phosphorylethanolamine dehydrogenase activity|alkylacylglycerophosphoethanolamine desaturase activity|dehydrogenase, alkyl-acylglycerophosphorylethanolamine|1-O-alkyl-2-acyl-sn-glycero-3-phosphorylethanolamine desaturase activity Catalysis of the reaction: O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine + donor-H2 + O2 = O-1-alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + acceptor + 2 H2O. GO:0050204 oxalomalate lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050204 EC:4.1.3.13|KEGG_REACTION:R00477|RHEA:22032|MetaCyc:OXALOMALATE-LYASE-RXN 3-oxalomalate glyoxylate-lyase activity|3-oxalomalate glyoxylate-lyase (oxaloacetate-forming) Catalysis of the reaction: 3-oxalomalate = glyoxylate + oxaloacetate. GO:0050205 oxamate carbamoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050205 KEGG_REACTION:R02937|RHEA:22984|EC:2.1.3.5|MetaCyc:OXAMATE-CARBAMOYLTRANSFERASE-RXN carbamoyl-phosphate:oxamate carbamoyltransferase activity|oxamic transcarbamylase activity Catalysis of the reaction: carbamoyl phosphate + oxamate = oxalurate + phosphate. CL:0000106 unipolar neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000106 Neuron with one neurite that extends from the cell body. GO:0050208 polysialic-acid O-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050208 RHEA:11604|MetaCyc:POLYSIALIC-ACID-O-ACETYLTRANSFERASE-RXN|EC:2.3.1.136 acetyl-CoA:polysialic-acid O-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + an alpha-2,8-linked polymer of sialic acid = CoA + polysialic acid acetylated at O-7 or O-9. CL:0000107 autonomic neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000107 A neruon whose cell body is within an autonomic ganglion. GO:0050209 polyvinyl-alcohol oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050209 RHEA:21688|EC:1.1.3.30|MetaCyc:POLYVINYL-ALCOHOL-OXIDASE-RXN polyvinyl-alcohol:oxygen oxidoreductase activity|dehydrogenase, polyvinyl alcohol|PVA oxidase activity Catalysis of the reaction: polyvinyl alcohol + O2 = oxidized polyvinyl alcohol + H2O2. CL:0000108 cholinergic neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000108 A neuron that uses acetylcholine as a vesicular neurotransmitter. GO:0015876 acetyl-CoA transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015876 The directed movement of acetyl-CoA into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis. GO:0015877 biopterin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015877 The directed movement of biopterin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Biopterin is a growth factor for certain protozoans and some insects; it is widely distributed in tissues and functions in a reduced form, tetrahydrobiopterin, as a hydroxylation coenzyme. GO:0015878 biotin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015878 vitamin B7 transport|vitamin H transport The directed movement of biotin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Biotin is cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions. GO:0015879 carnitine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015879 vitamin Bt transport The directed movement of carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carnitine is a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane. CL:0000100 motor neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000100 motoneuron An efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes or inhibits movement. GO:0015872 dopamine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015872 The directed movement of dopamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline. CL:0000101 sensory neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000101 Any neuron having a sensory function; an afferent neuron conveying sensory impulses. GO:0015873 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015873 GO:0015874 norepinephrine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015874 levarterenol transport|noradrenaline transport The directed movement of norepinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine. CL:0000103 bipolar neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000103 A type of interneuron that has two neurites, usually an axon and a dendrite, extending from opposite poles of an ovoid cell body. GO:0015875 obsolete vitamin or cofactor transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015875 vitamin or cofactor transport OBSOLETE. The directed movement of vitamins or cofactors into, out of or within a cell, or between cells. GO:0015870 acetylcholine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015870 The directed movement of acetylcholine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions. GO:0015871 choline transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015871 The directed movement of choline into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Choline (2-hydroxyethyltrimethylammonium) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine. GO:0050213 progesterone 5-alpha-reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050213 RHEA:21952|EC:1.3.1.30|MetaCyc:PROGESTERONE-5-ALPHA-REDUCTASE-RXN delta4-steroid 5alpha-reductase (progesterone)|progesterone 5alpha-reductase activity|progesterone 5a-reductase activity|5alpha-pregnan-3,20-dione:NADP+ 5-oxidoreductase activity|steroid 5-alpha-reductase activity Catalysis of the reaction: 5-alpha-pregnan-3,20-dione + NADP+ = progesterone + NADPH. GO:0050214 progesterone monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050214 MetaCyc:PROGESTERONE-MONOOXYGENASE-RXN|EC:1.14.99.4|RHEA:11984|KEGG_REACTION:R02212 progesterone,hydrogen-donor:oxygen oxidoreductase (hydroxylating)|progesterone hydroxylase activity Catalysis of the reaction: AH(2) + O(2) + progesterone = A + H(2)O + testosterone acetate. GO:0050211 procollagen galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050211 MetaCyc:PROCOLLAGEN-GALACTOSYLTRANSFERASE-RXN|RHEA:12637|Reactome:R-HSA-1981120|Reactome:R-HSA-1981128|EC:2.4.1.50 uridine diphosphogalactose-collagen galactosyltransferase activity|UDPgalactose:procollagen-5-hydroxy-L-lysine D-galactosyltransferase activity|UDP galactose-collagen galactosyltransferase activity|hydroxylysine galactosyltransferase activity|collagen hydroxylysyl galactosyltransferase activity|UDPgalactose:5-hydroxylysine-collagen galactosyltransferase activity|UDP-galactose:procollagen-5-hydroxy-L-lysine D-galactosyltransferase activity|collagen galactosyltransferase activity Catalysis of the reaction: UDP-galactose + procollagen 5-hydroxy-L-lysine = UDP + procollagen 5-(D-galactosyloxy)-L-lysine. GO:0050212 progesterone 11-alpha-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050212 EC:1.14.99.14|MetaCyc:PROGESTERONE-11-ALPHA-MONOOXYGENASE-RXN|KEGG_REACTION:R02214|RHEA:18205 progesterone 11a-monooxygenase activity|progesterone 11alpha-monooxygenase activity|progesterone 11-alpha-hydroxylase activity|progesterone,hydrogen-donor:oxygen oxidoreductase (11alpha-hydroxylating)|progesterone 11alpha-hydroxylase activity Catalysis of the reaction: AH(2) + O(2) + progesterone = 11alpha-hydroxyprogesterone + A + H(2)O. GO:0050217 propioin synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050217 MetaCyc:PROPIOIN-SYNTHASE-RXN|EC:4.1.2.35|KEGG_REACTION:R00038|RHEA:11100 4-hydroxy-3-hexanone propanal-lyase activity|4-hydroxy-3-hexanone aldolase activity|4-hydroxy-3-hexanone propanal-lyase (propanal-forming) Catalysis of the reaction: 4-hydroxyhexan-3-one = 2 propanal. GO:0050218 propionate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050218 MetaCyc:PROPIONATE--COA-LIGASE-RXN|EC:6.2.1.17|RHEA:20373 propionyl-CoA synthetase activity|propanoate:CoA ligase (AMP-forming) Catalysis of the reaction: ATP + propanoate + CoA = AMP + diphosphate + propanoyl-CoA. GO:0050215 propanediol dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050215 EC:4.2.1.28|MetaCyc:PROPANEDIOL-DEHYDRATASE-RXN|RHEA:14569|KEGG_REACTION:R02376 adenosylcobalamin-dependent diol dehydratase activity|1,2-propanediol dehydratase activity|diol dehydratase activity|DL-1,2-propanediol hydro-lyase activity|propanediol dehydrase activity|propane-1,2-diol hydro-lyase (propanal-forming)|coenzyme B12-dependent diol dehydrase activity|diol dehydrase activity|meso-2,3-butanediol dehydrase activity|propane-1,2-diol hydro-lyase activity|dioldehydratase activity Catalysis of the reaction: propane-1,2-diol = H(2)O + propanal. GO:0050216 propanediol-phosphate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050216 EC:1.1.1.7|MetaCyc:PROPANEDIOL-PHOSPHATE-DEHYDROGENASE-RXN|KEGG_REACTION:R04236|RHEA:21584 Catalysis of the reaction: NAD(+) + propane-1,2-diol 1-phosphate = H(+) + hydroxyacetone phosphate + NADH. CL:0000117 CNS neuron (sensu Vertebrata) biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000117 GO:0050219 prostaglandin-A1 delta-isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050219 MetaCyc:PROSTAGLANDIN-A1-DELTA-ISOMERASE-RXN|EC:5.3.3.9|KEGG_REACTION:R04565|RHEA:10460 prostaglandin-A1 D-isomerase activity|prostaglandin A isomerase activity|(13E)-(15S)-15-hydroxy-9-oxoprosta-10,13-dienoate delta10-delta11-isomerase activity Catalysis of the reaction: prostaglandin A1 = prostaglandin C1. CL:0000119 cerebellar Golgi cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000119 cerebellum Golgi cell|cerebellar Golgi neuron|Golgi cell|Golgi neuron Large intrinsic neuron located in the granule layer of the cerebellar cortex that extends its dendrites into the molecular layer where they receive contact from parallel fibers. The axon of the Golgi cell enters ramifies densely in the granule layer and enters into a complex arrangement with mossy fiber terminals and granule cell dendrites to form the cerebellar glomerulus. Llinas, Walton and Lang. In The Synaptic Organization of the Brain. 5th ed. 2004. GO:0015887 pantothenate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015887 pantothenate membrane transport|vitamin B5 transport|pantothenate transport The process in which pantothenate is transported across a membrane. Pantothenate is the anion of pantothenic acid, the amide of beta-alanine and pantoic acid; it is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods. GO:0015888 thiamine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015888 thiamin transport|vitamin B1 transport The directed movement of thiamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver. GO:0015889 cobalamin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015889 vitamin B12 transport The directed movement of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015883 FAD transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015883 flavin-adenine dinucleotide transport|flavin adenine dinucleotide transport The directed movement of flavin-adenine dinucleotide (FAD) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form. GO:0015884 folic acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015884 folate transport|vitamin B9 transport|vitamin M transport The directed movement of folic acid (pteroylglutamic acid) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines. CL:0000114 surface ectodermal cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000114 surface ectoderm cell|cell of surface ectoderm GO:0015885 5-formyltetrahydrofolate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015885 The directed movement of 5-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate, into, out of, within, or between cells, by means of some agent such as a transporter or pore. GO:0015886 heme transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015886 haem transport The directed movement of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CL:0000115 endothelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000115 endotheliocyte An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm. GO:0015880 coenzyme A transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015880 The directed movement of coenzyme A into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester. GO:0015881 creatine transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015881 creatine transport The directed movement of creatine across a membrane. GO:0015882 L-ascorbic acid transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015882 vitamin C transport|L-ascorbic acid transport|L-ascorbate transport The process in which L-ascorbic acid is transported across a lipid bilayer, from one side of a membrane to the other. L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, is vitamin C and has co-factor and anti-oxidant activities in many species. GO:0050210 prenyl-diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050210 RHEA:21496|EC:3.1.7.1|MetaCyc:PRENYL-PYROPHOSPHATASE-RXN prenyl-diphosphate diphosphohydrolase activity|prenyl-pyrophosphatase activity|prenol pyrophosphatase activity|prenylphosphatase activity Catalysis of the reaction: prenyl diphosphate + H2O = prenol + diphosphate. GO:0001213 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001213 GO:0050224 prunasin beta-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050224 KEGG_REACTION:R02558|EC:3.2.1.118|RHEA:16489|MetaCyc:PRUNASIN-BETA-GLUCOSIDASE-RXN prunasin hydrolase activity|prunasin b-glucosidase activity|prunasin beta-D-glucohydrolase activity Catalysis of the reaction: (R)-prunasin + H(2)O = D-glucose + mandelonitrile. UBERON:0000934 ventral nerve cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000934 ventral cord The pair of closely united ventral longitudinal nerves with their segmental ganglia that is characteristic of many elongate invertebrates (as earthworms)[BTO]. A large process bundle that runs along the vental mid-line extending from the ventral region of the nerve ring[WB]. The ventral cord is one of the distinguishing traits of the central nervous system of all arthropods (such as insects, crustaceans and arachnids) as well as many other invertebrates, such as the annelid worms[GO]. GO:0050225 pseudouridine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050225 RHEA:22448|KEGG_REACTION:R03315|EC:2.7.1.83|MetaCyc:PSEUDOURIDINE-KINASE-RXN pseudouridine kinase (phosphorylating)|ATP:pseudouridine 5'-phosphotransferase activity Catalysis of the reaction: ATP + pseudouridine = ADP + 2 H(+) + pseudouridine 5'-phosphate. GO:0001214 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001214 UBERON:0000935 anterior commissure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000935 commissura rostral|AC|commissura anterior cerebri|anterior cerebral commissure|commissura rostralis|paleocortical commissure|commissura anterior|anterior commissural nucleus|precommisure|rostral commissure A bundle of myelinated nerve fibers passing transversely through the lamina terminalis and connecting symmetrical parts of the two cerebral hemispheres; it consists of a smaller anterior part (pars anterior commissurae anterioris) and a larger posterior part (pars posterior commissurae anterioris). GO:0001215 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001215 UBERON:0000936 posterior commissure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000936 commissura posterior|commissura epithalami|caudal commissure|commissura epithalamica|epithalamic commissure|posterior commissure (Lieutaud) Rounded band of white fibers crossing the middle line on the dorsal aspect of the upper end of the cerebral aqueduct. It is important in the bilateral pupillary light reflex. Its fibers acquire their medullary sheaths early, but their connections have not been definitely determined. Most of them have their origin in a nucleus, the nucleus of the posterior commissure (nucleus of Darkschewitsch), which lies in the central gray substance of the upper end of the cerebral aqueduct, in front of the nucleus of the oculomotor nerve. Some are probably derived from the posterior part of the thalamus and from the superior colliculus, whereas others are believed to be continued downward into the medial longitudinal fasciculus. The posterior commissure interconnects the pretectal nuclei, mediating the consensual pupillary light reflex[WP]. Diencephalic tract which is located in the vicinity of the dorsal diencephalon and mesencephalon and connects the pretectal nuclei. From Neuroanatomy of the Zebrafish Brain[ZFA]. GO:0050222 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050222 GO:0050223 protocatechuate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050223 RHEA:22416|EC:4.1.1.63|MetaCyc:PROTOCATECHUATE-DECARBOXYLASE-RXN|KEGG_REACTION:R00822 3,4-dihydrobenzoate decarboxylase activity|3,4-dihydroxybenzoate decarboxylase activity|protocatechuate carboxy-lyase activity|3,4-dihydroxybenzoate carboxy-lyase (catechol-forming) Catalysis of the reaction: 3,4-dihydroxybenzoate + H(+) = catechol + CO(2). GO:0001216 DNA-binding transcription activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001216 sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in positive regulation of transcription|bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding|metal ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in positive regulation of transcription|transcriptional activator activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding|transcriptional activator activity, bacterial-type RNA polymerase proximal promoter sequence-specific DNA binding|bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|bacterial-type RNA polymerase transcriptional activator activity, metal ion regulated sequence-specific DNA binding A DNA-binding transcription factor activity that activates or increases transcription of specific gene sets. UBERON:0000930 stomodeum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000930 oral ectoderm|mouth primordium|stomodeal-hypophyseal primordium|mouth pit|stomatodeum|stomodaeum|primitive oral cavity|oral pit Anterior part of the embryonic digestive tract that develops into a mouth. The stomodeum includes as parts an invagination of the ectoderm and the stomodeal cavity. GO:0050228 pterin deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050228 EC:3.5.4.11|MetaCyc:PTERIN-DEAMINASE-RXN|RHEA:11904 acrasinase activity|2-amino-4-hydroxypteridine aminohydrolase activity Catalysis of the reaction: 2-amino-4-hydroxypteridine + H2O = 2,4-dihydroxypteridine + NH3. GO:0050229 pterocarpin synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050229 MetaCyc:PTEROCARPIN-SYNTHASE-RXN|RHEA:13533|EC:1.1.1.246 pterocarpan synthase activity|medicarpin:NADP+ 2'-oxidoreductase activity Catalysis of the reaction: medicarpin + NADP+ = vestitone + NADPH. GO:0001210 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001210 UBERON:0000931 proctodeum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000931 amnioproctodeal invagination|anus porus|proctodaeum|anal pit|embryonic proctodaeum Inward fold on the surface of the embryonic ectoderm that develops into an ectodermal terminal part of the digestive tract. GO:0050226 psychosine sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050226 EC:2.8.2.13|RHEA:14137|MetaCyc:PSYCHOSINE-SULFOTRANSFERASE-RXN psychosine sulphotransferase activity|PAPS:psychosine sulphotransferase activity|3'-phosphoadenylyl-sulfate:galactosylsphingosine sulfotransferase activity|3'-phosphoadenosine 5'-phosphosulfate-psychosine sulphotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + galactosylsphingosine = adenosine 3',5'-bisphosphate + psychosine sulfate. GO:0001211 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001211 CHEBI:144315 1-radyl-2-acyl-sn-glycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_144315 GO:0001212 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001212 UBERON:0000933 pharyngeal muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000933 muscle of pharynx|branchial muscle|tunica muscularis pharyngis|musculus pharyngis|pharynx muscle|muscle organ of pharynx|branchial muscles|musculi pharyngis|pharynx muscle organ A muscle that acts on the pharynx[WP, vetted]. GO:0050227 pteridine oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050227 RHEA:12777|EC:1.17.3.1|MetaCyc:PTERIDINE-OXIDASE-RXN 2-amino-4-hydroxypteridine:oxygen oxidoreductase (7-hydroxylating) Catalysis of the reaction: 2-amino-4-hydroxypteridine + O2 = 2-amino-4,7-dihydroxypteridine + unknown. GO:0015858 nucleoside transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015858 The directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UBERON:0000939 imaginal disc biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000939 imaginal disk one of the parts of a holometabolous insect larva that will become a portion of the outside of the adult insect during the pupal transformation. GO:0015859 intracellular nucleoside transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015859 The directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide), within a cell. GO:0015854 guanine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015854 The directed movement of guanine, 2-amino-6-hydroxypurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015855 pyrimidine nucleobase transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015855 pyrimidine transmembrane transport|pyrimidine base transport|pyrimidine transport|pyrimidine base transmembrane transport The directed movement of pyrimidine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015856 cytosine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015856 cytosine transmembrane transport The directed movement of cytosine, 4-amino-2-hydroxypyrimidine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015857 uracil transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015857 The directed movement of uracil, 2,4-dioxopyrimidine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015850 organic hydroxy compound transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015850 organic alcohol transport The directed movement of an organic hydroxy compound (organic alcohol) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An organic hydroxy compound is an organic compound having at least one hydroxy group attached to a carbon atom. GO:0015851 nucleobase transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015851 nucleobase transmembrane transport The directed movement of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015852 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015852 GO:0015853 adenine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015853 adenine transmembrane transport The directed movement of adenine, 6-aminopurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:37196 bismuth molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37196 GO:0050220 prostaglandin-E synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050220 Reactome:R-HSA-265295|RHEA:12893|KEGG_REACTION:R02265|EC:5.3.99.3|Reactome:R-HSA-2161660|MetaCyc:PROSTAGLANDIN-E-SYNTHASE-RXN endoperoxide isomerase activity|Prostaglandin-H(2) E-isomerase activity|prostaglandin endoperoxide E isomerase activity|prostaglandin endoperoxide E2 isomerase activity|prostaglandin H-E isomerase activity|PGE2 isomerase activity|(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate E-isomerase activity|prostaglandin-H2 E-isomerase activity|PGE isomerase activity|PGH-PGE isomerase activity|prostaglandin R-prostaglandin E isomerase activity Catalysis of the reaction: prostaglandin H(2) = prostaglandin E(2). GO:0001217 DNA-binding transcription repressor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001217 bacterial-type DNA binding transcription repressor activity|copper ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in negative regulation of transcription|bacterial-type RNA polymerase transcriptional repressor activity, copper ion regulated sequence-specific DNA binding|cadmium ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in negative regulation of transcription|sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in negative regulation of transcription|bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding|bacterial-type RNA polymerase transcriptional repressor activity, cadmium ion regulated sequence-specific DNA binding|transcriptional repressor activity, bacterial-type RNA polymerase proximal promoter sequence-specific DNA binding|metal ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in negative regulation of transcription|bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|transcriptional repressor activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding|bacterial-type RNA polymerase transcriptional repressor activity, metal ion regulated sequence-specific DNA binding A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets. GO:0050221 prostaglandin-E2 9-reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050221 MetaCyc:PROSTAGLANDIN-E2-9-REDUCTASE-RXN|EC:1.1.1.189|Reactome:R-HSA-2161651|RHEA:24508 9-keto-prostaglandin E2 reductase activity|PGE2-9-ketoreductase activity|PGE2-9-OR|prostaglandin E2-9-oxoreductase activity|prostaglandin-E2 9-oxoreductase activity|PGE-9-ketoreductase activity|9-keto-prostaglandin E(2) reductase activity|9-ketoprostaglandin reductase activity|PGE2 9-ketoreductase activity|PGE(2) 9-oxoreductase activity|(5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP+ 9-oxidoreductase activity|prostaglandin E 9-ketoreductase activity|PGE(2) 9-ketoreductase activity|PGE2 9-oxoreductase activity|prostaglandin-E(2) 9-oxoreductase activity|reductase, 15-hydroxy-9-oxoprostaglandin Catalysis of the reaction: (5Z,13E)-(15S)-9-alpha,11-alpha,15-trihydroxyprosta-5,13-dienoate + NADP+ = (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate + NADPH. GO:0001218 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001218 GO:0001219 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001219 UBERON:0000923 germ layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000923 primary germ layer|embryonic germ layer|embryonic tissue|embryonic germ layers|germinal layer A layer of cells produced during the process of gastrulation during the early development of the animal embryo, which is distinct from other such layers of cells, as an early step of cell differentiation. The three types of germ layers are the endoderm, ectoderm, and mesoderm. GO:0050235 pyridoxal 4-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050235 KEGG_REACTION:R01707|RHEA:21336|MetaCyc:PYRIDOXAL-4-DEHYDROGENASE-RXN|EC:1.1.1.107 pyridoxal dehydrogenase activity|pyridoxal:NAD+ 4-oxidoreductase activity Catalysis of the reaction: NAD(+) + pyridoxal = 4-pyridoxolactone + H(+) + NADH. GO:0001224 RNA polymerase II transcription coregulator binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001224 RNA polymerase II transcription cofactor binding Interacting selectively and non-covalently with a transcription coregulator for RNA polymerase II, any protein involved in regulation of transcription via protein-protein interactions with RNA polymerase II transcription factors and other transcription regulatory proteins. Cofactors do not bind DNA directly, but rather mediate protein-protein interactions between regulatory transcription factors and the basal transcription machinery of RNA polymerase II. UBERON:0000924 ectoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000924 embryonic ectoderm Primary germ layer that is the outer of the embryo's three germ layers and gives rise to epidermis and neural tissue. GO:0001225 RNA polymerase II transcription coactivator binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001225 Interacting selectively and non-covalently with an RNA polymerase II transcription coactivator, any protein involved in positive regulation of transcription of RNA polymerase II via protein-protein interactions with transcription factors and other proteins that positively regulate transcription. Transcription coactivators do not bind DNA directly, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery of RNA polymerase II. GO:0050236 pyridoxine:NADP 4-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050236 KEGG_REACTION:R01708|EC:1.1.1.65|MetaCyc:PYRIDOXINE-4-DEHYDROGENASE-RXN|RHEA:16129 pyridoxal reductase activity|PL reductase activity|pyridoxol dehydrogenase activity|pyridoxin dehydrogenase activity|pyridoxine dehydrogenase activity|pyridoxine:NADP 4-oxidoreductase activity Catalysis of the reaction: NADP(+) + pyridoxine = H(+) + NADPH + pyridoxal. GO:0050233 pyranose oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050233 MetaCyc:PYRANOSE-OXIDASE-RXN|EC:1.1.3.10|KEGG_REACTION:R00302|RHEA:10552 pyranose-2-oxidase activity|pyranose:oxygen 2-oxidoreductase activity|glucose 2-oxidase activity Catalysis of the reaction: D-glucose + O(2) = 2-dehydro-D-glucose + H(2)O(2). GO:0001226 RNA polymerase II transcription corepressor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001226 Interacting selectively and non-covalently with an RNA polymerase II transcription corepressor, any protein involved in negative regulation of transcription by RNA polymerase II via protein-protein interactions with transcription factors and other proteins that negatively regulate transcription. Transcription corepressors do not bind DNA directly, but rather mediate protein-protein interactions between repressing transcription factors and the basal transcription machinery of RNA polymerase II. UBERON:0000925 endoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000925 entoderm Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut. GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding|sequence-specific distal enhancer binding RNA polymerase II transcription factor activity involved in negative regulation of transcription|RNA polymerase II transcriptional repressor activity, metal ion regulated proximal promoter sequence-specific DNA binding|RNA polymerase II transcriptional repressor activity, metal ion regulated core promoter proximal region sequence-specific binding|RNA polymerase II distal enhancer sequence-specific DNA-binding transcription factor activity involved in negative regulation of transcription|transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding|transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding|metal ion regulated sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|distal enhancer DNA-binding transcription repressor activity, RNA polymerase II-specific|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|proximal promoter DNA-binding transcription repressor activity, RNA polymerase II-specific|transcriptional repressor activity, metal ion regulated sequence-specific DNA binding|metal ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in negative regulation of transcription A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets transcribed by RNA polymerase II. GO:0050234 pyrazolylalanine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050234 MetaCyc:PYRAZOLYLALANINE-SYNTHASE-RXN|KEGG_REACTION:R02378|RHEA:24512|EC:4.2.1.50 L-serine hydro-lyase (adding pyrazole)|L-serine hydro-lyase [adding pyrazole; 3-(pyrazol-1-yl)-L-alanine-forming]|beta-pyrazolylalaninase activity Catalysis of the reaction: L-serine + pyrazole = 3-(pyrazol-1-yl)-L-alanine + H(2)O. UBERON:0000926 mesoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000926 mesodermal mantle|embryonic mesoderm|entire mesoderm The middle germ layer of the embryo, between the endoderm and ectoderm. GO:0001220 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001220 GO:0050239 pyrithiamine deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050239 RHEA:14537|EC:3.5.4.20|MetaCyc:PYRITHIAMIN-DEAMINASE-RXN 1-(4-amino-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium-bromide aminohydrolase activity Catalysis of the reaction: 1-(4-amino-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium bromide + H2O = 1-(4-hydroxy-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium bromide + NH3. GO:0001221 transcription coregulator binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001221 transcription cofactor binding Interacting selectively and non-covalently with a transcription coregulator, any protein involved in regulation of transcription via protein-protein interactions with transcription factors and other transcription regulatory proteins. Cofactors do not bind DNA directly, but rather mediate protein-protein interactions between regulatory transcription factors and the basal transcription machinery. UBERON:0000920 egg chorion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000920 chorion (egg)|chorion A protective, noncellular membrane that surrounds the eggs of various animals including insects and fish [GO]. GO:0050237 pyridoxine 4-oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050237 EC:1.1.3.12|MetaCyc:PYRIDOXINE-4-OXIDASE-RXN|RHEA:15033 pyridoxin 4-oxidase activity|pyridoxol 4-oxidase activity|pyridoxine:oxygen 4-oxidoreductase activity Catalysis of the reaction: pyridoxine + O2 = pyridoxal + H2O2. GO:0001222 transcription corepressor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001222 Interacting selectively and non-covalently with a transcription corepressor, any protein involved in negative regulation of transcription via protein-protein interactions with transcription factors and other proteins that negatively regulate transcription. Transcription corepressors do not bind DNA directly, but rather mediate protein-protein interactions between repressing transcription factors and the basal transcription machinery. GO:0050238 pyridoxine 5-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050238 EC:1.1.99.9|MetaCyc:PYRIDOXINE-5-DEHYDROGENASE-RXN|RHEA:14497 pyridoxine:acceptor 5-oxidoreductase activity|pyridoxine 5'-dehydrogenase activity|pyridoxol 5-dehydrogenase activity|pyridoxal-5-dehydrogenase activity|pyridoxin 5-dehydrogenase activity|pyridoxine:(acceptor) 5-oxidoreductase activity Catalysis of the reaction: pyridoxine + acceptor = isopyridoxal + reduced acceptor. GO:0001223 transcription coactivator binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001223 Interacting selectively and non-covalently with a transcription coactivator, any protein involved in positive regulation of transcription via protein-protein interactions with transcription factors and other proteins that positively regulate transcription. Transcription coactivators do not bind DNA directly, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery. UBERON:0000922 embryo biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000922 developing organism|developmental tissue|embryonic organism Anatomical entity that comprises the organism in the early stages of growth and differentiation that are characterized by cleavage, the laying down of fundamental tissues, and the formation of primitive organs and organ systems. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant. GO:0015869 protein-DNA complex transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015869 DNA-protein complex transport The directed movement of protein-DNA complexes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UBERON:0000927 mesectoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000927 MesEc A double row of cells which are located at the midline from the end of gastrulations. The morphology of these cells is distinct from adjacent ectodermal cells - they are elongated such that one end remains exposed to the outside of the embryo at the mideline while the other end bissects the internalised mesoderm. GO:0015865 purine nucleotide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015865 The directed movement of a purine nucleotide, any compound consisting of a purine nucleoside esterified with (ortho)phosphate, into, out of or within a cell. GO:0015866 ADP transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015866 The directed movement of ADP, adenosine diphosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015867 ATP transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015867 The directed movement of ATP, adenosine triphosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015868 purine ribonucleotide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015868 The directed movement of a purine ribonucleotide, any compound consisting of a purine ribonucleoside (a purine organic base attached to a ribose sugar) esterified with (ortho)phosphate, into, out of or within a cell. GO:0015861 cytidine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015861 The directed movement of cytidine, cytosine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015862 uridine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015862 The directed movement of uridine, uracil riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015863 xanthosine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015863 The directed movement of xanthosine, xanthine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015864 pyrimidine nucleoside transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015864 The directed movement of a pyrimidine nucleoside, a pyrimidine base covalently bonded to a ribose or deoxyribose sugar, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015860 purine nucleoside transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015860 purine nucleoside membrane transport|purine nucleoside transport The process in which a purine nucleoside is transported across a membrane. A purine nucleoside is a purine base covalently bonded to a ribose or deoxyribose sugar. GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001228 RNA polymerase II transcriptional activator activity, metal ion regulated proximal promoter sequence-specific DNA binding|RNA polymerase II transcriptional activator activity, zinc ion regulated proximal promoter sequence-specific DNA binding|RNA polymerase II transcriptional activator activity, metal ion regulated core promoter proximal region sequence-specific binding|RNA polymerase II transcriptional activator activity, zinc ion regulated core promoter proximal region sequence-specific binding|RNA polymerase II distal enhancer sequence-specific DNA-binding transcription factor activity involved in positive regulation of transcription|copper ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in positive regulation of transcription|metal ion regulated sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcriptional activator activity, copper ion regulated proximal promoter sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding|transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding|transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|distal enhancer DNA-binding transcription activator activity, RNA polymerase II-specific|zinc ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in positive regulation of transcription|transcriptional activator activity, metal ion regulated sequence-specific DNA binding|metal ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in positive regulation of transcription|proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific|transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding|sequence-specific distal enhancer binding RNA polymerase II transcription factor activity involved in positive regulation of transcription A DNA-binding transcription factor activity that activates or increases transcription of specific gene sets transcribed by RNA polymerase II. GO:0050231 putrescine carbamoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050231 RHEA:21936|KEGG_REACTION:R01399|MetaCyc:PUTRESCINE-CARBAMOYLTRANSFERASE-RXN|EC:2.1.3.6 putrescine synthase activity|putrescine transcarbamylase activity|carbamoyl-phosphate:putrescine carbamoyltransferase activity|PTCase activity Catalysis of the reaction: carbamoyl phosphate + putrescine = N-carbamoylputrescine + H(+) + phosphate. GO:0050232 putrescine oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050232 RHEA:18273|MetaCyc:PUTRESCINE-OXIDASE-RXN|EC:1.4.3.10 putrescine:oxygen oxidoreductase (deaminating) Catalysis of the reaction: putrescine + O2 + H2O = 4-aminobutanal + NH3 + H2O2. GO:0050230 purine imidazole-ring cyclase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050230 MetaCyc:PURINE-IMIDAZOLE-RING-CYCLASE-RXN|EC:4.3.2.4 DNA-4,6-diamino-5-formamidopyrimidine 8-C,9-N-lyase (cyclizing; DNA-adenine-forming)|DNA-4,6-diamino-5-formamidopyrimidine C8-N9-lyase (cyclizing; DNA-adenine-forming)|DNA-4,6-diamino-5-formamidopyrimidine 8-C,9-N-lyase (cyclizing) Catalysis of the reaction: DNA 4,6-diamino-5-formamidopyrimidine = DNA adenine + H2O. GO:0050246 questin monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050246 EC:1.14.13.43|RHEA:10836|MetaCyc:QUESTIN-MONOOXYGENASE-RXN|KEGG_REACTION:R02417 questin oxygenase activity|questin,NADPH:oxygen oxidoreductase (hydroxylating, anthraquinone-ring-opening) Catalysis of the reaction: H(+) + NADPH + O(2) + questin = demethylsulochrin + NADP(+). UBERON:0000912 mucus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000912 Mucus is a bodily fluid consisting of a slippery secretion of the lining of the mucous membranes in the body. It is a viscous colloid containing antiseptic enzymes (such as lysozyme) and immunoglobulins. Mucus is produced by goblet cells in the mucous membranes that cover the surfaces of the membranes. It is made up of mucins and inorganic salts suspended in water. GO:0050247 raucaffricine beta-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050247 RHEA:14557|MetaCyc:RAUCAFFRICINE-BETA-GLUCOSIDASE-RXN|EC:3.2.1.125|KEGG_REACTION:R03703 raucaffricine b-glucosidase activity|raucaffricine beta-D-glucohydrolase activity|raucaffricine glucosidase activity|raucaffricine beta-D-glucosidase activity Catalysis of the reaction: H(2)O + raucaffricine = D-glucose + vomilenine. UBERON:0000913 interstitial fluid biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000913 intercellular fluid|tissue fluid Interstitial fluid is a bodily fluid consisting of a solution which bathes and surrounds the cells of multicellular animals. It is the main component of the extracellular fluid, which also includes plasma and transcellular fluid. GO:0050244 pyruvate oxidase (CoA-acetylating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050244 KEGG_REACTION:R00211|EC:1.2.3.6|MetaCyc:PYRUVATE-OXIDASE-COA-ACETYLATING-RXN|RHEA:21912 pyruvate:oxygen 2-oxidoreductase (CoA-acetylating) Catalysis of the reaction: CoA + H(+) + O(2) + pyruvate = acetyl-CoA + CO(2) + H(2)O(2). UBERON:0000914 organismal segment biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000914 segment|serial element One of the repeated divisions of the whole organism. GO:0050245 quercitrinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050245 KEGG_REACTION:R02436|RHEA:17465|MetaCyc:QUERCITRINASE-RXN|EC:3.2.1.66 quercitrin 3-L-rhamnohydrolase activity Catalysis of the reaction: H(2)O + quercitrin = L-rhamnose + quercetin. UBERON:0000915 thoracic segment of trunk biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000915 anterior subdivision of trunk|upper body|upper trunk|thorax Subdivision of trunk that lies between the head and the abdomen. GO:0050248 Renilla-luciferin 2-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050248 RHEA:14765|MetaCyc:RENILLA-LUCIFERIN-2-MONOOXYGENASE-RXN|EC:1.13.12.5 luciferase activity|Renilla-type luciferase activity|Renilla-luciferin:oxygen 2-oxidoreductase (decarboxylating)|aequorin activity|luciferase (Renilla luciferin) Catalysis of the reaction: Renilla luciferin + O2 = oxidized Renilla luciferin + CO2 + light. GO:0050249 Renilla-luciferin sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050249 KEGG_REACTION:R03138|EC:2.8.2.10|RHEA:20481|MetaCyc:RENILLA-LUCIFERIN-SULFOTRANSFERASE-RXN Renilla-luciferin sulphotransferase activity|luciferin sulfotransferase activity|3'-phosphoadenylyl-sulfate:Renilla luciferin sulfotransferase activity|luciferin sulfokinase (3'-phosphoadenylyl sulfate:luciferin sulfotransferase)|luciferin sulfokinase activity Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + Renilla luciferin = adenosine 3',5'-diphosphate + H(+) + luciferyl sulfate. UBERON:0000916 abdomen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000916 adult abdomen|abdominopelvic region|abdominopelvis|belly|celiac region The subdivision of the vertebrate body between the thorax and pelvis. The ventral part of the abdomen contains the abdominal cavity and visceral organs. The dorsal part includes the abdominal section of the vertebral column. GO:0015836 lipid-linked peptidoglycan transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015836 lipid-linked murein transport The directed movement of lipid-linked peptidoglycans into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015837 amine transport biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0015837 amine/polyamine transport The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015838 amino-acid betaine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015838 betaine transport The directed movement of betaine, the N-trimethyl derivative of an amino acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015839 cadaverine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015839 The directed movement of cadaverine, 1,5-pentanediamine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015832 obsolete holin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015832 holin OBSOLETE. (Was not defined before being made obsolete). GO:1902000 homogentisate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902000 homogentisate degradation|homogentisate breakdown|homogentisate catabolism The chemical reactions and pathways resulting in the breakdown of homogentisate. GO:0015833 peptide transport biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0015833 The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015834 peptidoglycan-associated peptide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015834 muropeptide transport|peptidoglycan peptide transport|murein peptide transport The directed movement of peptidoglycan peptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Peptidoglycan peptides are the oligopeptides found in peptidoglycan networks which cross-link the polysaccharide chains. GO:0015835 peptidoglycan transport biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0015835 murein transport The directed movement of peptidoglycans, a class of glycoconjugates found in bacterial cell walls, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015830 diaminopimelate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015830 The directed movement of diaminopimelate, the anion of 2,6-diaminoheptanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015831 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015831 CHEBI:37175 organic hydride biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37175 GO:0050242 pyruvate, phosphate dikinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050242 EC:2.7.9.1|KEGG_REACTION:R00206|RHEA:10756|MetaCyc:PYRUVATEORTHOPHOSPHATE-DIKINASE-RXN PPDK|ATP:pyruvate, phosphate phosphotransferase activity|orthophosphate dikinase pyruvate|pyruvate-inorganic phosphate dikinase activity|pyruvate,phosphate dikinase activity|pyruvate-phosphate dikinase activity|pyruvate-phosphate ligase activity|pyruvic-phosphate dikinase activity|pyruvate, Pi dikinase activity|pyruvate-phosphate dikinase (phosphorylating)|pyruvic-phosphate ligase activity|pyruvate,orthophosphate dikinase activity Catalysis of the reaction: ATP + phosphate + pyruvate = AMP + diphosphate + 2 H(+) + phosphoenolpyruvate. GO:0050243 pyruvate dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050243 EC:1.2.1.51|KEGG_REACTION:R00210|RHEA:17425|MetaCyc:PYRUVATE-DEHYDROGENASE-NADP%2b-RXN pyruvate:NADP+ oxidoreductase activity|pyruvate:NADP+ 2-oxidoreductase (CoA-acetylating)|pyruvate:NADP(+) oxidoreductase activity Catalysis of the reaction: CoA + NADP(+) + pyruvate = acetyl-CoA + CO(2) + NADPH. GO:0050240 pyrogallol 1,2-oxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050240 KEGG_REACTION:R03246|RHEA:19673|MetaCyc:PYROGALLOL-12-OXYGENASE-RXN|EC:1.13.11.35 pyrogallol 1,2-dioxygenase activity|1,2,3-trihydroxybenzene:oxygen 1,2-oxidoreductase (decyclizing) Catalysis of the reaction: O(2) + pyrogallol = (Z)-5-oxohex-2-enedioate + 2 H(+). CHEBI:37176 mononuclear parent hydride biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37176 GO:0050241 pyrroline-2-carboxylate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050241 EC:1.5.1.1|MetaCyc:PYRROLINE-2-CARBOXYLATE-REDUCTASE-RXN L-proline:NAD(P)+ 2-oxidoreductase activity|delta1-pyrroline-2-carboxylate reductase activity Catalysis of the reaction: L-proline + NAD(P)+ = 1-pyrroline-2-carboxylate + NAD(P)H + H+. GO:0050257 riboflavin phosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050257 RHEA:20409|KEGG_REACTION:R00550|EC:2.7.1.42|MetaCyc:RIBOFLAVIN-PHOSPHOTRANSFERASE-RXN alpha-D-glucose-1-phosphate:riboflavin 5'-phosphotransferase activity|G-1-P phosphotransferase activity|riboflavine phosphotransferase activity|D-glucose-1-phosphate:riboflavin 5'-phosphotransferase activity Catalysis of the reaction: alpha-D-glucose 1-phosphate + riboflavin = D-glucose + FMN. GO:0001202 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001202 GO:0050258 riboflavinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050258 MetaCyc:RIBOFLAVINASE-RXN|RHEA:11408|EC:3.5.99.1|KEGG_REACTION:R01732 riboflavin hydrolase activity Catalysis of the reaction: H(2)O + H(+) + riboflavin = D-ribitol + lumichrome. GO:0001203 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001203 OIO:Subset biolink:OntologyClass go-plus http://www.geneontology.org/formats/oboInOwl#Subset GO:0050255 ribitol 2-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050255 EC:1.1.1.56|KEGG_REACTION:R01895|RHEA:20053|MetaCyc:RIBITOL-2-DEHYDROGENASE-RXN ribitol:NAD+ 2-oxidoreductase activity|ribitol dehydrogenase D (mutant enzyme with different properties)|ribitol dehydrogenase B (mutant enzyme with different properties)|adonitol dehydrogenase activity|ribitol dehydrogenase A (wild type) Catalysis of the reaction: D-ribitol + NAD(+) = D-ribulose + H(+) + NADH. GO:0001204 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001204 GO:0050256 ribitol-5-phosphate 2-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050256 EC:1.1.1.137|MetaCyc:RIBITOL-5-PHOSPHATE-2-DEHYDROGENASE-RXN dehydrogenase, ribitol 5-phosphate|D-ribitol-5-phosphate:NAD(P)+ 2-oxidoreductase activity Catalysis of the reaction: D-ribitol 5-phosphate + NAD(P)+ = D-ribulose 5-phosphate + NAD(P)H + H+. CHEBI:168396 mycophenolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_168396 GO:0001205 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001205 CHEBI:37193 elemental lead biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37193 GO:0050259 ribose 1-dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050259 RHEA:11676|MetaCyc:RIBOSE-1-DEHYDROGENASE-NADP+-RXN|KEGG_REACTION:R01079|EC:1.1.1.115 NADP-pentose-dehydrogenase activity|D-ribose:NADP+ 1-oxidoreductase activity|D-ribose dehydrogenase (NADP+) Catalysis of the reaction: H(2)O + NADP(+) + ribofuranose = D-ribonate + 2 H(+) + NADPH. GO:1902009 positive regulation of toxin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902009 up regulation of toxin transport|activation of toxin transport|up-regulation of toxin transport|upregulation of toxin transport Any process that activates or increases the frequency, rate or extent of toxin transport. CHEBI:37190 silicon coordination entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37190 GO:0001200 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001200 GO:0001201 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001201 CHEBI:37191 silicon oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37191 GO:1902007 regulation of toxin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902007 Any process that modulates the frequency, rate or extent of toxin transport. GO:1902008 negative regulation of toxin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902008 downregulation of toxin transport|down-regulation of toxin transport|inhibition of toxin transport|down regulation of toxin transport Any process that stops, prevents or reduces the frequency, rate or extent of toxin transport. GO:1902005 regulation of proline biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902005 regulation of proline anabolism|regulation of proline synthesis|regulation of proline formation|regulation of proline biosynthesis Any process that modulates the frequency, rate or extent of proline biosynthetic process. GO:1902006 negative regulation of proline biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902006 inhibition of proline biosynthesis|negative regulation of proline formation|down-regulation of proline formation|inhibition of proline anabolism|inhibition of proline synthesis|negative regulation of proline biosynthesis|down-regulation of proline biosynthesis|down-regulation of proline biosynthetic process|down regulation of proline anabolism|inhibition of proline formation|downregulation of proline anabolism|down regulation of proline synthesis|down regulation of proline formation|downregulation of proline biosynthesis|downregulation of proline biosynthetic process|downregulation of proline synthesis|downregulation of proline formation|down regulation of proline biosynthetic process|down regulation of proline biosynthesis|negative regulation of proline anabolism|down-regulation of proline anabolism|inhibition of proline biosynthetic process|negative regulation of proline synthesis|down-regulation of proline synthesis Any process that stops, prevents or reduces the frequency, rate or extent of proline biosynthetic process. GO:1902003 regulation of amyloid-beta formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902003 regulation of beta-amyloid formation Any process that modulates the frequency, rate or extent of amyloid-beta formation. GO:0015847 putrescine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015847 The directed movement of putrescine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Putrescine is 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine. GO:0015848 spermidine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015848 The directed movement of spermidine, N-(3-aminopropyl)-1,4-diaminobutane, a polyamine formed by the transfer of a propylamine group from decarboxylated S-adenosylmethionine to putrescine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:1902004 positive regulation of amyloid-beta formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902004 upregulation of beta-amyloid formation|positive regulation of beta-amyloid formation|up-regulation of beta-amyloid formation|activation of beta-amyloid formation|up regulation of beta-amyloid formation Any process that activates or increases the frequency, rate or extent of amyloid-beta formation. GO:0015849 organic acid transport biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0015849 The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:1902001 fatty acid transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902001 The process in which a fatty acid is transported across a membrane. GO:1902002 obsolete protein phosphorylation involved in cellular protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902002 protein phosphorylation involved in cellular protein catabolism|protein amino acid phosphorylation involved in cellular protein degradation|protein amino acid phosphorylation involved in cellular protein breakdown|protein amino acid phosphorylation involved in cellular protein catabolism|protein phosphorylation involved in cellular protein degradation|protein amino acid phosphorylation involved in cellular protein catabolic process|protein phosphorylation involved in cellular protein breakdown OBSOLETE. Any protein phosphorylation that is involved in cellular protein catabolic process. GO:0015843 methylammonium transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015843 The directed movement of methylammonium into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:1902010 negative regulation of translation in response to endoplasmic reticulum stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902010 inhibition of protein biosynthetic process involved in response to endoplasmic reticulum stress|negative regulation of protein anabolism involved in ER stress response|downregulation of protein biosynthetic process involved in ER stress response|downregulation of protein biosynthetic process involved in response to ER stress|negative regulation of protein anabolism involved in response to ER stress|protein biosynthetic process inhibitor activity involved in ER stress response|protein biosynthesis inhibitor activity involved in ER stress response|down regulation of protein biosynthetic process involved in response to ER stress|inhibition of protein biosynthetic process involved in response to ER stress|negative regulation of protein synthesis involved in response to ER stress|negative regulation of protein formation involved in response to endoplasmic reticulum stress|protein biosynthesis inhibitor activity involved in response to ER stress|protein biosynthetic process inhibitor activity involved in response to ER stress|negative regulation of protein biosynthesis involved in ER stress response|down-regulation of protein biosynthetic process involved in ER stress response|negative regulation of protein biosynthetic process involved in ER stress response|negative regulation of protein formation involved in response to ER stress|negative regulation of protein synthesis involved in response to endoplasmic reticulum stress|down regulation of protein biosynthetic process involved in response to endoplasmic reticulum stress|negative regulation of translation involved in response to ER stress|negative regulation of protein anabolism involved in response to endoplasmic reticulum stress|downregulation of protein biosynthetic process involved in response to endoplasmic reticulum stress|inhibition of protein biosynthetic process involved in ER stress response|protein biosynthetic process inhibitor activity involved in response to endoplasmic reticulum stress|protein biosynthesis inhibitor activity involved in response to endoplasmic reticulum stress|negative regulation of translation involved in ER stress response|negative regulation of protein biosynthetic process involved in response to ER stress|down-regulation of protein biosynthetic process involved in response to endoplasmic reticulum stress|negative regulation of protein biosynthesis involved in response to endoplasmic reticulum stress|down-regulation of protein biosynthetic process involved in response to ER stress|negative regulation of protein biosynthetic process involved in response to endoplasmic reticulum stress|negative regulation of protein biosynthesis involved in response to ER stress|negative regulation of protein formation involved in ER stress response|negative regulation of protein synthesis involved in ER stress response|down regulation of protein biosynthetic process involved in ER stress response Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of endoplasmic reticulum stress. GO:1902011 poly(ribitol phosphate) teichoic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902011 poly(ribitol phosphate) teichoic acid metabolism The chemical reactions and pathways involving poly(ribitol phosphate) teichoic acid. GO:0015844 monoamine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015844 The directed movement of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015845 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015845 GO:0015846 polyamine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015846 The directed movement of polyamines, organic compounds containing two or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015840 urea transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015840 The directed movement of urea into, out of or within the cell. Urea is the water-soluble compound H2N-CO-NH2. GO:0015841 chromaffin granule amine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015841 The directed movement of amines into, out of or within chromaffin granules. GO:0015842 aminergic neurotransmitter loading into synaptic vesicle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015842 The active transport of aminergic neurotransmitters into a synaptic vesicle. This import is fuelled by an electrochemical gradient across the vesicle membrane, established by the action proton pumps. GO:0050250 retinal oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050250 EC:1.2.3.11|RHEA:22520|MetaCyc:RETINAL-OXIDASE-RXN retinene oxidase activity|retinal:oxygen oxidoreductase activity Catalysis of the reaction: retinal + O2 + H2O = retinoate + H2O2. GO:0050253 retinyl-palmitate esterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050253 EC:3.1.1.-|MetaCyc:RETINYL-PALMITATE-ESTERASE-RXN|RHEA:21508|Reactome:R-HSA-2404133|Reactome:R-HSA-975594|Reactome:R-HSA-975593|KEGG_REACTION:R02368|Reactome:R-HSA-8848355 retinyl ester hydrolase activity|retinyl-palmitate palmitohydrolase activity|retinyl palmitate hydrolase activity|retinyl palmitate hydrolyase activity Catalysis of the reaction: retinyl palmitate + H2O = retinol + palmitate + H+. GO:0001206 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001206 GO:0050254 rhodopsin kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050254 Reactome:R-HSA-2581474|RHEA:23356|MetaCyc:2.7.11.14-RXN|EC:2.7.11.14 ATP:rhodopsin phosphotransferase activity|cone opsin kinase activity|GRK1|G-protein-coupled receptor kinase 1 activity|STK14|rhodopsin kinase (phosphorylating) activity|opsin kinase activity|GPCR kinase 1 activity|RK|opsin kinase (phosphorylating) activity|GRK7 Catalysis of the reaction: ATP + rhodopsin = ADP + phosphorhodopsin. GO:0001207 histone displacement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001207 The removal of histones, including histone dimers, from nucleosomes within chromatin. GO:0001208 histone H2A-H2B dimer displacement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001208 The removal of a H2A-H2B histone dimer from a nucleosome within chromatin. GO:0050251 retinol isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050251 Reactome:R-HSA-2465926|KEGG_REACTION:R02369|RHEA:19141|MetaCyc:RETINOL-ISOMERASE-RXN all-trans-retinol 11-cis-trans-isomerase activity|all-trans-retinol isomerase activity Catalysis of the reaction: all-trans-retinol = 11-cis-retinol. GO:0050252 retinol O-fatty-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050252 Reactome:R-HSA-8848585|Reactome:R-HSA-2465919|EC:2.3.1.76|RHEA:11488|MetaCyc:RETINOL-O-FATTY-ACYLTRANSFERASE-RXN retinol acyltransferase activity|acyl-CoA:retinol O-acyltransferase activity|retinol fatty-acyltransferase activity Catalysis of the reaction: acyl-CoA + retinol = CoA + retinyl ester. GO:0001209 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001209 GO:1990596 histone H3-K4 deacetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990596 The modification of histone H3 by the removal of an acetyl group from lysine at position 4 of the histone. GO:1990597 AIP1-IRE1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990597 IRE1-DAB2IP complex|AIP1-ERN1 complex|IRE1alpha-AIP1 complex A protein complex consisting of IRE1 (inositol-requiring enzyme-1) bound to AIP1 (ASK1-interacting protein 1/DAB2-interacting protein). GO:1990598 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990598 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990599 Catalysis of the hydrolysis of ester linkages within 3' overhang single-stranded deoxyribonucleic acid by creating internal breaks. GO:1990592 protein K69-linked ufmylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990592 A protein ufmylation process in which a polymer of the ubiquitin-like protein UFM1 is formed by linkages between lysine residues at position 69 of the UFM1 monomers, is added to a protein. GO:1990593 nascent polypeptide-associated complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990593 NACA binding|NAC binding Interacting selectively and non-covalently with the nascent polypeptide-associated complex, which is a heterodimeric protein complex that can reversibly bind to ribosomes and is located in direct proximity to newly synthesized polypeptide chains as they emerge from the ribosome. GO:1990594 L-altrarate dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990594 RHEA:44028 L-talarate dehydratase activity Catalysis of the reaction: L-altrarate = 5-dehydro-4-deoxy-D-glucarate + H(2)O. GO:1990595 mast cell secretagogue receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990595 Combining with basic secretagogues to initiate pseudo-allergic reactions in mast cells. GO:2001039 negative regulation of cellular response to drug biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001039 Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to drug. GO:1990590 ATF1-ATF4 transcription factor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990590 IntAct:EBI-10043123|IntAct:EBI-10043370 Transcription factor complex consisting of ATF1 and ATF4 subunits that is capable of binding to cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') of the GRP78 (HSPA5) promoter. Involved in the ER stress response pathway. GO:1990591 asparagine transmembrane import into vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990591 The directed movement of asparagine into the vacuole across the vacuolar membrane. GO:2001031 positive regulation of cellular glucuronidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001031 positive regulation of cellular glucuronoside biosynthesis|positive regulation of cellular glucuronoside biosynthetic process|positive regulation of cellular glucuronide biosynthetic process|positive regulation of cellular glucuronide biosynthesis Any process that activates or increases the frequency, rate or extent of cellular glucuronidation. GO:2001032 regulation of double-strand break repair via nonhomologous end joining biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001032 regulation of NHEJ Any process that modulates the frequency, rate or extent of double-strand break repair via nonhomologous end joining. GO:2001033 negative regulation of double-strand break repair via nonhomologous end joining biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001033 negative regulation of NHEJ Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via nonhomologous end joining. GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001034 positive regulation of NHEJ Any process that activates or increases the frequency, rate or extent of double-strand break repair via nonhomologous end joining. GO:2001035 regulation of tongue muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001035 Any process that modulates the frequency, rate or extent of tongue muscle cell differentiation. GO:2001036 negative regulation of tongue muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001036 Any process that stops, prevents or reduces the frequency, rate or extent of tongue muscle cell differentiation. GO:2001037 positive regulation of tongue muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001037 Any process that activates or increases the frequency, rate or extent of tongue muscle cell differentiation. GO:2001038 regulation of cellular response to drug biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001038 Any process that modulates the frequency, rate or extent of cellular response to drug. CHEBI:76760 EC 3.1.* (ester hydrolase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76760 CHEBI:76761 EC 3.2.* (glycosylase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76761 CHEBI:76764 EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76764 GO:2001030 negative regulation of cellular glucuronidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001030 negative regulation of cellular glucuronoside biosynthetic process|negative regulation of cellular glucuronoside biosynthesis|negative regulation of cellular glucuronide biosynthesis|negative regulation of cellular glucuronide biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of cellular glucuronidation. CHEBI:76779 EC 3.4.21.26 (prolyl oligopeptidase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76779 CHEBI:27802 2,3-dihydroxybenzenesulfonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27802 CHEBI:27803 cis-2-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27803 CHEBI:76778 IMP residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76778 CHEBI:27804 cyclohexanecarboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27804 CHEBI:62130 beta-D-Galp-(1->4)-beta-D-GlcpNAc-(1->3)-beta-D-Galp-(1->4)-D-GlcpNAc biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62130 GO:2001042 negative regulation of septum digestion after cytokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001042 negative regulation of cytokinetic cell separation Any process that stops, prevents or reduces the frequency, rate or extent of the process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis. GO:2001043 positive regulation of septum digestion after cytokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001043 positive regulation of cell separation after cytokinesis|positive regulation of cytokinetic cell separation Any process that activates or increases the frequency, rate or extent of the process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis. GO:2001044 regulation of integrin-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001044 regulation of integrin-mediated signalling pathway Any process that modulates the frequency, rate or extent of integrin-mediated signaling pathway. GO:2001045 negative regulation of integrin-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001045 negative regulation of integrin-mediated signalling pathway Any process that stops, prevents or reduces the frequency, rate or extent of integrin-mediated signaling pathway. GO:2001046 positive regulation of integrin-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001046 positive regulation of integrin-mediated signalling pathway Any process that activates or increases the frequency, rate or extent of integrin-mediated signaling pathway. GO:2001047 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2001047 GO:2001048 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2001048 GO:2001049 regulation of tendon cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001049 regulation of tenocyte differentiation|regulation of muscle attachment cell differentiation Any process that modulates the frequency, rate or extent of tendon cell differentiation. CHEBI:27809 L-4-hydroxyglutamic semialdehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27809 CHEBI:76770 EC 3.11.* (hydrolases acting on C-P bonds) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76770 CHEBI:76775 EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76775 GO:2001040 positive regulation of cellular response to drug biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001040 Any process that activates or increases the frequency, rate or extent of cellular response to drug. CHEBI:76773 EC 3.1.1.* (carboxylic ester hydrolase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76773 GO:2001041 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2001041 CHEBI:76788 EC 3.4.14.* (dipeptidyl- and tripeptidyl-peptidases) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76788 CHEBI:76789 EC 2.4.1.* (hexosyltransferase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76789 CHEBI:62141 S-[(2E,6E)-farnesyl]-L-cysteine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62141 CHEBI:86110 O-[S-(6Z)-hexadecenoylpantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86110 CHEBI:86113 (25R)-4beta,26-dihydroxycholesterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86113 CHEBI:86115 (25R)-3beta,4beta-dihydroxycholest-5-en-26-al biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86115 GO:2001053 regulation of mesenchymal cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001053 regulation of mesenchymal cell apoptosis Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process. CHEBI:86116 (25R)-3beta,4beta-dihydroxycholest-5-en-26-oate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86116 GO:2001054 negative regulation of mesenchymal cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001054 negative regulation of mesenchymal cell apoptosis Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process. CL:0000186 myofibroblast cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000186 MFB An animal cell that has characteristics of both a fibroblast cell and a smooth muscle cell. CL:0000187 muscle cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000187 myocyte|muscle fiber A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns. GO:2001055 positive regulation of mesenchymal cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001055 positive regulation of mesenchymal cell apoptosis Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process. CL:0000188 cell of skeletal muscle biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000188 skeletal muscle cell A somatic cell located in skeletal muscle. GO:2001056 positive regulation of cysteine-type endopeptidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001056 positive regulation of lysosomal cysteine-type endopeptidase|positive regulation of thiol endopeptidase activity Any process that activates or increases the frequency, rate or extent of cysteine-type endopeptidase activity. CHEBI:86119 1-hexadecanoyl-2-[(5Z,8Z,11Z)-icosatrienoyl]-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86119 GO:2001057 reactive nitrogen species metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001057 RNS metabolic process|RNS metabolism|reactive nitrogen species metabolism The chemical reactions and pathways involving a reactive nitrogen species. CL:0000189 slow muscle cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000189 slow muscle fiber A muscle cell that develops tension more slowly than a fast-twitch fiber. GO:2001058 D-tagatose 6-phosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001058 D-tagatose 6-phosphate metabolism The chemical reactions and pathways involving a D-tagatose 6-phosphate. GO:2001059 D-tagatose 6-phosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001059 UniPathway:UPA00704 D-tagatose 6-phosphate catabolism The chemical reactions and pathways resulting in the breakdown of a D-tagatose 6-phosphate. CHEBI:76782 EC 3.4.15.* (peptidyl-dipeptidase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76782 CL:0000180 estradiol secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000180 A steroid hormone secreting cell that secretes estradiol. GO:2001050 negative regulation of tendon cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001050 negative regulation of tenocyte differentiation|negative regulation of muscle attachment cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of tendon cell differentiation. CL:0000182 hepatocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000182 The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated. CHEBI:76787 EC 3.4.11.* (aminopeptidase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76787 GO:2001051 positive regulation of tendon cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001051 positive regulation of tenocyte differentiation|positive regulation of muscle attachment cell differentiation Any process that activates or increases the frequency, rate or extent of tendon cell differentiation. CL:0000183 contractile cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000183 A cell whose primary function is to shorten. GO:2001052 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2001052 CHEBI:76785 EC 3.1.26.* (endoribonucleases producing 5'-phosphomonoesters) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76785 CHEBI:62150 (3,4-dimethoxyphenyl)methanol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62150 CHEBI:86102 1-tetradecanoyl-2-[(5Z,8Z,11Z,14Z)-eicosatetraenoyl]-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86102 GO:2001064 cellooligosaccharide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_2001064 Interacting selectively and non-covalently with cellooligosaccharide. CL:0000197 sensory receptor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000197 receptor cell A cell that is capable of detection of a stimulus involved in sensory perception. GO:2001065 mannan binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_2001065 mannoglycan binding Interacting selectively and non-covalently with mannan. GO:2001066 amylopectin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_2001066 Interacting selectively and non-covalently with amylopectin. CL:0000199 mechanoreceptor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000199 mechanoreceptor A cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system. GO:2001067 pullulan binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_2001067 Interacting selectively and non-covalently with pullulan. GO:2001068 arabinoxylan binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_2001068 Interacting selectively and non-covalently with arabinoxylan. GO:2001069 glycogen binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_2001069 liver starch binding|animal starch binding Interacting selectively and non-covalently with glycogen. CHEBI:76790 EC 2.4.2.* (pentosyltransferase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76790 CHEBI:76791 EC 3.1.27.* (endoribonucleases producing other than 5'-phosphomonoesters) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76791 GO:2001060 D-glycero-D-manno-heptose 7-phosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001060 D-glycero-D-manno-heptose 7-phosphate metabolism The chemical reactions and pathways involving a D-glycero-D-manno-heptose 7-phosphate. CL:0000192 smooth muscle cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000192 smooth muscle fiber|SMCs|myocytes, smooth muscle|non-striated muscle cell A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast). CHEBI:76797 EC 2.5.1.18 (glutathione transferase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76797 GO:2001061 D-glycero-D-manno-heptose 7-phosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001061 UniPathway:UPA00041 D-glycero-D-manno-heptose 7-phosphate biosynthesis The chemical reactions and pathways resulting in the formation of a D-glycero-D-manno-heptose 7-phosphate. GO:2001062 xylan binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_2001062 Interacting selectively and non-covalently with xylan. CHEBI:76796 EC 3.4.22.* (cysteine endopeptidase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76796 GO:2001063 glucomannan binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_2001063 Interacting selectively and non-covalently with glucomannan. GO:1990552 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990552 GO:1990553 mitochondrial 5'-adenylyl sulfate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990553 The process in which 5'-adenylyl sulfate is transported across a mitochondrial membrane, into or out of the mitochondrion. GO:1990554 mitochondrial 3'-phospho-5'-adenylyl sulfate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990554 The process in which 3'-phospho-5'-adenylyl sulfate is transported across a mitochondrial membrane, into or out of the mitochondrion. GO:1990555 mitochondrial oxaloacetate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990555 The process in which oxaloacetate is transported across a mitochondrial membrane, into or out of the mitochondrion. PR:000014543 secretin biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000014543 SCT A protein that is a translation product of the human SCT gene or a 1:1 ortholog thereof. PR:000014544 secretin receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000014544 SCTR|SCT-R A glucagon-like receptor that is a translation product of the human SCTR gene or a 1:1 ortholog thereof. GO:1990550 mitochondrial alpha-ketoglutarate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990550 mitochondrial 2-oxoglutarate transmembrane transport The process in which alpha-ketoglutarate is transported across a mitochondrial membrane, into or out of the mitochondrion. GO:1990551 mitochondrial 2-oxoadipate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990551 The process in which 2-oxoadipate is transported across a mitochondrial membrane, into or out of the mitochondrion. CHEBI:62164 N-acetylmannosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62164 CHEBI:86131 5alpha-cholesta-8,14-dien-3beta-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86131 CHEBI:86132 (9Z,12Z)-hexadeca-9,12,15-trienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86132 CHEBI:86133 1-[(9Z)-octadecenoyl]-2-[(9Z,12Z,15Z)-octadecatrienoyl]-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86133 CHEBI:86135 (5Z,9Z,12Z,15Z)-octadecatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86135 CHEBI:86136 (5Z,9Z,12Z)-octadecatrienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86136 CHEBI:86137 1-hexadecanoyl-2-[(5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl]-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86137 CL:0000163 endocrine cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000163 endocrinocyte A cell of an endocrine gland, ductless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions. CL:0000164 enteroendocrine cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000164 An endocrine cell that is located in the epithelium of the gastrointestinal tract or in the pancreas. CHEBI:86139 N-methyl-L-alpha-amino acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86139 CL:0000165 neuroendocrine cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000165 neurosecretory cell An endocrine cell that has the specialized function to produce and secrete hormones in response to neuronal signals. CL:0000166 chromaffin cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000166 phaeochromocyte A cell that stores epinephrine secretory vesicles. During times of stress, the nervous system signals the vesicles to secrete their hormonal content. Their name derives from their ability to stain a brownish color with chromic salts. Characteristically, they are located in the adrenal medulla and paraganglia of the sympathetic nervous system. CL:0000167 peptide hormone secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000167 CL:0000168 insulin secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000168 CL:0000169 type B pancreatic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000169 beta cell of pancreatic islet|B-cell of pancreatic islet|pancreatic islet core|pancreatic B-cell|beta cell|type B enteroendocrine cell|beta cell islet|pancreatic B cell|pancreatic beta cell|insulin-secreting cell A cell that secretes insulin and is located towards the center of the islets of Langerhans. GO:1990556 mitochondrial isopropylmalate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990556 The process in which 2-isopropylmalate(2-) is transported across a mitochondrial membrane, into or out of the mitochondrion. GO:1990557 mitochondrial sulfate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990557 The process in which sulfate is transported across a mitochondrial membrane, into or out of the mitochondrion. CL:0000160 goblet cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000160 chalice cell A cell of the epithelial lining that produce and secrete mucins. GO:1990558 mitochondrial malonate(1-) transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990558 The process in which malonate(1-) is transported across a mitochondrial membrane, into or out of the mitochondrion. CL:0000161 acid secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000161 GO:1990559 mitochondrial coenzyme A transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990559 The process in which coenzyme A is transported across a mitochondrial membrane, into or out of the mitochondrion. GO:1990563 extracellular exosome complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990563 exosome complex|extracellular vesicular exosome complex A protein complex that is wholly or partially contained within the lumen or membrane of the extracellular vesicular exosome. GO:1990564 protein polyufmylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990564 Covalent attachment of the ubiquitin-like protein UFM1 to a protein, forming an UFM1 chain. GO:1990565 HSP90-CDC37 chaperone complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990565 IntAct:EBI-9990540|IntAct:EBI-9990131 A protein kinase chaperone complex required for the proper folding, maturation and stabilization of target proteins (mostly signalling protein kinases, some steroid hormone receptors), usually during or immediately after completion of translation. The highly conserved, phosphorylated CDC37-Ser13 (vertebrates) or cdc37-Ser14 (yeast) is essential for complex assembly and target protein binding. CDC37-Ser13 (Ser14) is phosphorylated by Casein kinase II (CK2), which in turn is a target of CDC37 creating a positive feedback loop. Complex binding also prevents rapid ubiquitin-dependent proteosomal degradation of target proteins. GO:1990566 I(KACh) inward rectifier potassium channel complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990566 IntAct:EBI-9975539 Kir3.1-Kir3.4 G protein-coupled atrial inward rectifier potassium channel complex|muscarinic potassium channel complex|GIRK1-GIRK4 G protein-coupled atrial inward rectifier potassium channel complex An inward rectifier potassium channel complex expressed in cardiac muscle, specifically the sinoatrial node and atria, where it controls the heart rate, via regulation by G protein-coupled receptor signalling. In mammals it is composed of GIRK1 (or Kir3.1) and GIRK4 (or Kir3.4) subunits. CHEBI:62170 N-acyl-D-mannosamine phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62170 GO:1990560 obsolete DNA methyltransferase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990560 DNA methyltransferase binding OBSOLETE. Interacting selectively and non-covalently with a DNA methyltransferase. GO:1990561 obsolete regulation of transcription from RNA polymerase II promoter in response to copper ion starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990561 OBSOLETE. Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is deprived of copper ions. GO:1990562 syndecan-syntenin-ALIX complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990562 IntAct:EBI-9985210|IntAct:EBI-9985797 exosome complex An exosome complex that is assembled in the multivesicular body (MVB) membrane and chaperoned to the exosome by the ESCRT-III machinery. GO:2001006 regulation of cellulose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001006 regulation of cellulose biosynthesis|regulation of cellulose anabolism|regulation of cellulose synthesis|regulation of cellulose formation Any process that modulates the frequency, rate or extent of cellulose biosynthetic process. CHEBI:86120 (11Z)-hexadec-11-enoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86120 GO:2001007 negative regulation of cellulose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001007 negative regulation of cellulose synthesis|negative regulation of cellulose formation|negative regulation of cellulose anabolism|negative regulation of cellulose biosynthesis Any process that stops, prevents or reduces the frequency, rate or extent of cellulose biosynthetic process. GO:2001008 positive regulation of cellulose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001008 positive regulation of cellulose formation|positive regulation of cellulose biosynthesis|positive regulation of cellulose anabolism|positive regulation of cellulose synthesis Any process that activates or increases the frequency, rate or extent of cellulose biosynthetic process. CHEBI:86121 1-hexadecanoyl-2-[(8Z,11Z,14Z)-eicosatrienoyl]-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86121 CHEBI:86122 (10E,12Z)-hexadecadienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86122 GO:2001009 regulation of plant-type cell wall cellulose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001009 regulation of cellulose biosynthesis during cell wall biosynthesis|regulation of cell wall cellulose biosynthesis Any process that modulates the frequency, rate or extent of plant-type cell wall cellulose biosynthetic process. CL:0000174 steroid hormone secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000174 CL:0000175 luteal cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000175 lutein cell A progesterone secreting cell in the corpus luteum. The large luteal cells develop from the granulosa cells. The small luteal cells develop from the theca cells. CHEBI:86128 2-methyl-L-tryptophan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86128 GO:2001000 regulation of xylan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001000 regulation of xylan degradation|regulation of xylan catabolism|regulation of xylan breakdown Any process that modulates the frequency, rate or extent of xylan catabolic process. CL:0000176 ecdysteroid secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000176 GO:2001001 negative regulation of xylan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001001 negative regulation of xylan breakdown|negative regulation of xylan catabolism|negative regulation of xylan degradation Any process that stops, prevents or reduces the frequency, rate or extent of xylan catabolic process. CL:0000177 testosterone secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000177 CL:0000178 Leydig cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000178 interstitial cell|interstitial cell of Leydig A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis. GO:2001002 positive regulation of xylan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001002 positive regulation of xylan catabolism|positive regulation of xylan degradation|positive regulation of xylan breakdown Any process that activates or increases the frequency, rate or extent of xylan catabolic process. CL:0000179 progesterone secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000179 GO:2001003 regulation of pectin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001003 regulation of pectin catabolism|regulation of pectin degradation|regulation of pectin breakdown Any process that modulates the frequency, rate or extent of pectin catabolic process. GO:2001004 negative regulation of pectin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001004 negative regulation of pectin degradation|negative regulation of pectin breakdown|negative regulation of pectin catabolism Any process that stops, prevents or reduces the frequency, rate or extent of pectin catabolic process. GO:2001005 positive regulation of pectin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001005 positive regulation of pectin degradation|positive regulation of pectin catabolism|positive regulation of pectin breakdown Any process that activates or increases the frequency, rate or extent of pectin catabolic process. GO:1990567 DPS complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990567 A protein serine/threonine phosphatase complex that in S. pombe consists of the proteins Dis2, Ppn1, and Swd22. CL:0000170 glucagon secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000170 glucagon-secreting cell A cell that secretes glucagon. CL:0000171 pancreatic A cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000171 alpha cell of islet of Langerhans|pancreatic alpha cell A type of enteocrine cell found in the periphery of the islets of Langerhans that secretes glucagon. GO:1990568 obsolete MIS18 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990568 IntAct:EBI-9872194|IntAct:EBI-9873644 MIS18 complex OBSOLETE. A centromere complex assembly protein that is required for the deposition of CENP-A on the centromere. The Mis18 complex localizes to centromeres just prior to the pre-nucleosomal HJURP/CENP-A/H4 complex and is absolutely required for the CENP-A-specific chaperone, Holliday junction recognition protein (HJURP) to reach the centromeres. Plk1 phosphorylation activates Mis18 complex recruitment to the centromeres during G1. CDK phosphorylation of MISBP1 during G2 and mitosis, prior to the metaphase-to-anaphase transition, negatively regulates complex assembly. GO:1990569 UDP-N-acetylglucosamine transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990569 UDP-N-acetylglucosamine transport The process in which UDP-N-acetylglucosamine is transported across a membrane. CL:0000172 somatostatin secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000172 CL:0000173 pancreatic D cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000173 delta cell of islet|D-cell of pancreatic islet|delta cell of pancreatic islet|pancreatic D-cell|somatostatin-secreting pancreatic cell|pancreatic delta cell A D cell located in the pancreas. Peripherally placed within the islets like type A cells; contains somatostatin. GO:1990574 meiotic spindle astral microtubule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990574 Any of the meiotic spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell. GO:1990575 mitochondrial L-ornithine transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990575 mitochondrial ornithine transport|mitochondrial ornithine transmembrane transport The process in which L-ornithine is transported across a mitochondrial membrane, into or out of the mitochondrion. GO:1990576 G protein-coupled glucose receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990576 G-protein coupled glucose receptor activity Combining with an extracellular glucose molecule and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. GO:1990577 C-terminal protein demethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990577 The removal of a methyl group from the C-terminal amino acid of a protein. CHEBI:144378 N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_144378 GO:1990570 GDP-mannose transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990570 GDP-mannose transport The process in which GDP-mannose is transported across a membrane. GO:1990571 meiotic centromere clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990571 centromere clustering during meiosis|homologous chromosome movement towards spindle pole in meiosis I prometaphase The process by which centromeres/kinetochores attach to and migrate along microtubules to become localized to clusters at the spindle pole body during a meiotic prometaphase I. GO:1990572 TERT-RMRP complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990572 telomerase reverse transcriptase:RMRP RNA complex A ribonucleoprotein complex that has RNA-directed RNA polymerase (RdRP) activity, and is composed of telomerase reverse transcriptase (TERT) and the non-coding RNA component of mitochondrial RNA processing endoribonuclease (RMRP). GO:1990573 potassium ion import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990573 potassium ion uptake|potassium import|potassium ion import The directed movement of potassium ions from outside of a cell, across the plasma membrane and into the cytosol. GO:2001017 regulation of retrograde axon cargo transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001017 regulation of retrograde axonal transport Any process that modulates the frequency, rate or extent of retrograde axon cargo transport. CL:0000149 visual pigment cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000149 pigment cell GO:2001018 negative regulation of retrograde axon cargo transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001018 negative regulation of retrograde axonal transport Any process that stops, prevents or reduces the frequency, rate or extent of retrograde axon cargo transport. GO:2001019 positive regulation of retrograde axon cargo transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001019 positive regulation of retrograde axonal transport Any process that activates or increases the frequency, rate or extent of retrograde axon cargo transport. CHEBI:144370 3-(2-isocyanovinyl)indole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_144370 GO:2001010 negative regulation of plant-type cell wall cellulose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001010 negative regulation of cellulose biosynthesis during cell wall biosynthesis|negative regulation of cell wall cellulose biosynthesis Any process that stops, prevents or reduces the frequency, rate or extent of plant-type cell wall cellulose biosynthetic process. GO:2001011 positive regulation of plant-type cell wall cellulose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001011 positive regulation of cellulose biosynthesis during cell wall biosynthesis|positive regulation of cell wall cellulose biosynthesis Any process that activates or increases the frequency, rate or extent of plant-type cell wall cellulose biosynthetic process. GO:2001012 mesenchymal cell differentiation involved in renal system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001012 mesenchymal cell differentiation involved in urinary system development|mesenchymal cell differentiation involved in urinary tract development The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the renal system as it progresses from its formation to the mature state. CL:0000145 professional antigen presenting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000145 APC A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response. GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001013 Any epithelial cell proliferation that is involved in renal tubule morphogenesis. GO:2001014 regulation of skeletal muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001014 Any process that modulates the frequency, rate or extent of skeletal muscle cell differentiation. CL:0000146 simple columnar epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000146 GO:2001015 negative regulation of skeletal muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001015 Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle cell differentiation. CL:0000147 pigment cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000147 chromatophore|chromatocyte A pigment cell is a cell that contains pigment granules. GO:2001016 positive regulation of skeletal muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001016 Any process that activates or increases the frequency, rate or extent of skeletal muscle cell differentiation. CL:0000148 melanocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000148 melanophore A pigment cell derived from the neural crest. Contains melanin-filled pigment granules, which gives a brown to black appearance. GO:1990578 perinuclear endoplasmic reticulum membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990578 perinuclear ER membrane The membrane of the perinuclear endoplasmic reticulum, which is the portion of endoplasmic reticulum, the intracellular network of tubules and cisternae, that occurs near the nucleus. GO:1990579 peptidyl-serine trans-autophosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990579 serine transautophosphorylation|serine autophosphorylation in trans The phosphorylation of a peptidyl-serine to form peptidyl-O-phospho-L-serine on an identical protein. For example, phosphorylation by the other kinase within a homodimer. GO:1990585 hydroxyproline O-arabinosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990585 HPAT Catalysis of the reaction: UDP-beta-L-arabinofuranose + a [protein]-trans-4-hydroxy-L-proline <=> a protein-O-(beta-L-arabinofuranose)-trans-4-hydroxy-L-proline + UDP + H+. GO:1990586 divisome complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990586 A protein complex required for prokaryotic cell division (FtsZ-dependent cytokinesis). These complexes are assembled and recruited to the cell septum in a strictly controlled sequence and co-ordinate invagination of the cell membrane, inward growth of the peptidoglycan layer, constriction of the outer membrane and separation of daughter cells. GO:1990587 FtsQBL complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990587 IntAct:EBI-9547109 FtsB-FtsL-FtsQ complex A protein complex required for prokaryotic cell division (FtsZ-dependent cytokinesis). Part of the divisome. Assembled independently of the other divisome components in the cytoplasm prior to transport to the cell septum. In E. coli consists of FtsB, FtsL and FtsQ. GO:1990588 FtsBL complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990588 IntAct:EBI-9997581 FtsB-FtsL complex A protein complex required for prokaryotic cell division (FtsZ-dependent cytokinesis). Part of the divisome. Assembled independently of the other divisome components in the cytoplasm prior to transport to the cell septum. In E. coli consists of FtsB and FtsL. CHEBI:144368 1,2-diacyl-sn-glycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_144368 CHEBI:62192 plastoquinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62192 GO:1990581 obsolete lysosome lysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990581 lysosome lysis|lysosomal lysis OBSOLETE. The rupture of the lysosomal membrane and loss of contents as a result of osmotic change, G-protein-driven disintegration, or unspecified cause. GO:1990582 obsolete intracellular membrane-bounded organelle binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990582 intracellular membrane-bounded organelle binding|intracellular membrane-enclosed organelle binding OBSOLETE. The temporary binding of a protein or protein complex to the membrane of an intracellular membrane-bounded organelle. CHEBI:62193 biotin sulfoxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62193 GO:1990583 phospholipase D activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990583 Increases the activity of the enzyme phospholipase D. GO:1990584 cardiac Troponin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990584 IntAct:EBI-9980814 cTnC:cTnI:cTnT A complex of accessory proteins (cardiac troponin T, cardiac troponin I and cardiac troponin C) found associated with actin in cardiac muscle thin filaments; involved in calcium regulation important for muscle contraction. CHEBI:62196 polysaccharide acid oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62196 GO:2001028 positive regulation of endothelial cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001028 Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis. CHEBI:86141 (9Z,12E)-octadecadienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86141 GO:2001029 regulation of cellular glucuronidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001029 regulation of cellular glucuronoside biosynthesis|regulation of cellular glucuronoside biosynthetic process|regulation of cellular glucuronide biosynthesis|regulation of cellular glucuronide biosynthetic process Any process that modulates the frequency, rate or extent of cellular glucuronidation. CHEBI:62197 S-[(2E,6E)-farnesyl]-L-cysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62197 CHEBI:86142 (9Z,12E)-hexadecadienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86142 CHEBI:86143 (14Z)-hexadecenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86143 CHEBI:62194 (S)-carnitinyl-CoA betaine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62194 GO:1990580 regulation of cytoplasmic translational termination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990580 Any process that modulates the frequency, rate or extent of cytoplasmic translational termination. CHEBI:86144 (14E)-hexadecenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86144 CHEBI:86145 (7alpha,22R)-dihydroxycholesterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86145 CHEBI:86146 (24S,25)-epoxy-7alpha-hydroxycholesterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86146 CHEBI:62198 lipid A-core biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62198 CHEBI:86147 (7Z,10Z)-hexadecadienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86147 CHEBI:62199 galactosyl-(glucosyl)3-(heptosyl)3-(KDO)2-lipid A-bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62199 CHEBI:86148 (8E,10E,12Z)-octadecatrienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86148 GO:2001020 regulation of response to DNA damage stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001020 regulation of DNA damage response|regulation of response to genotoxic stress|regulation of cellular DNA damage response|regulation of cellular response to DNA damage stimulus Any process that modulates the frequency, rate or extent of response to DNA damage stimulus. GO:2001021 negative regulation of response to DNA damage stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001021 negative regulation of cellular DNA damage response|negative regulation of DNA damage response|negative regulation of cellular response to DNA damage stimulus|negative regulation of response to genotoxic stress Any process that stops, prevents or reduces the frequency, rate or extent of response to DNA damage stimulus. CL:0000153 glycosaminoglycan secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000153 hyaluronic acid secreting cell|GAG secreting cell A cell that secretes glycosaminoglycans. GO:2001022 positive regulation of response to DNA damage stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001022 positive regulation of DNA damage response|positive regulation of cellular DNA damage response|positive regulation of cellular response to DNA damage stimulus|positive regulation of response to genotoxic stress Any process that activates or increases the frequency, rate or extent of response to DNA damage stimulus. CL:0000154 protein secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000154 GO:2001023 regulation of response to drug biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001023 regulation of drug resistance|regulation of drug susceptibility/resistance Any process that modulates the frequency, rate or extent of response to drug. GO:2001024 negative regulation of response to drug biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001024 negative regulation of drug resistance|negative regulation of drug susceptibility/resistance Any process that stops, prevents or reduces the frequency, rate or extent of response to drug. GO:2001025 positive regulation of response to drug biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001025 positive regulation of drug resistance|positive regulation of drug susceptibility/resistance Any process that activates or increases the frequency, rate or extent of response to drug. CL:0000157 surfactant secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000157 A cell that specializes in secretion of surfactant in the alveoli of the lung. GO:2001026 regulation of endothelial cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001026 Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis. CL:0000158 club cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000158 Clara cell|bronchiolar non-ciliated cell|club cell of bronchiole Epithelial progenitor cell of the lung. Club cells are dome-shaped with short microvilli but no cilia. They function to protect the bronchiolar epithelium. Club cells also multiply and differentiate into ciliated cells to regenerate the bronchiolar epithelium. CL:0000159 seromucus secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000159 GO:2001027 negative regulation of endothelial cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001027 Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis. GO:1990589 ATF4-CREB1 transcription factor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990589 IntAct:EBI-10043332|IntAct:EBI-10043081 Transcription factor complex consisting of ATF4 and CREB1 subunits that is capable of binding to cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') as part of the positive regulation of transcription. Regulatory targets include the GRP78 (HSPA5) promoter in humans, whose activation by this complex is part of the ER stress response pathway. CL:0000150 glandular epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000150 A specialized epithelial cell that is capable of synthesizing and secreting certain biomolecules. CL:0000151 secretory cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000151 A cell that specializes in controlled release of one or more substances. CHEBI:27757 4-chlorobiphenyl biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27757 GO:1990510 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990510 GO:1990511 piRNA biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990511 Piwi-associated RNA biosynthetic process The chemical reactions and pathways resulting in the formation of piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism. UBERON:0010380 enteric nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010380 the neurons that innervate the esophagus, stomach, small and large bowel CHEBI:27754 methacrylyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27754 CHEBI:27750 ethyl acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27750 UBERON:0010388 proximal segment of rib biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010388 proximal part of rib|proximal rib|costal part of rib|vertebral part of rib|proximal rib segment The segment of the rib that connects to a vertebra[MP]. a small part of the rib composed of the head, neck, tuberculum and a short proximal part of the body[PMID] UBERON:0010389 pterygoid bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010389 lamina lateralis (processus pterygoideus)|lamina lateralis processi pterygoideus ossis sphenoidalis|lateral plate of sphenoid|lateral plate of pterygoid process|lateral lamina of pterygoid process|inner plate of pterygoid process|pterygoid|lateral pterygoid plate A bone which corresponds to the inner plate of the pterygoid process of the human skull, but which, in all vertebrates below mammals, is not connected with the posterior nares, but serves to connect the palatine bones with the point of suspension of the lower jaw UBERON:0010386 Peyer's patch follicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010386 peyer's patch follicle A lymphoid follicle that is part of a Peyer's patch. UBERON:0010387 Peyer's patch T cell area biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010387 The Peyer's patch area normally occupied by T lymphocytes GO:1990516 ribonucleotide excision repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990516 The pathway by which a ribonucleotide is removed from DNA and replaced by a deoxyribonucleotide. The ribonucleotide is incised by RNase H2, and further excised by an endonuclease. The resulting 1 nt gap is then repaired by DNA polymerase and DNA ligase. GO:1990517 obsolete protein localization to photoreceptor outer segment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990517 OBSOLETE. A process in which a protein is transported to, or maintained in, a location within a photoreceptor outer segment, which is a portion of a modified sensory cilium. GO:1990518 single-stranded 3'-5' DNA helicase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990518 Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of single-stranded DNA; drives the unwinding of the DNA helix in the direction 3' to 5'. GO:1990519 pyrimidine nucleotide import into mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990519 mitochondrial pyrimidine nucleotide import The process in which a pyrimidine nucleotide is transported across the mitochondrial inner membrane, into the mitochondrial matrix. GO:1990512 Cry-Per complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990512 IntAct:EBI-9696219|IntAct:EBI-9695878|IntAct:EBI-9696328|IntAct:EBI-9695921|IntAct:EBI-9693126|IntAct:EBI-9695942|IntAct:EBI-9696345|IntAct:EBI-9696310|IntAct:EBI-9693260|IntAct:EBI-9694282|IntAct:EBI-9696293|IntAct:EBI-9696270 Nuclear transcriptional repressor complex that is capable of negatively regulating CLOCK-BMAL-dependent transactivation of genes in a delayed negative feedback manner which generates circadian rhythms. GO:1990513 CLOCK-BMAL transcription complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990513 IntAct:EBI-9696901|IntAct:EBI-9696921|IntAct:EBI-9696951|IntAct:EBI-9696362 CLOCK/BMAL complex Transcription factor complex which interacts with E-box regulatory elements in target genes, including Period (Per1, Per2, Per3) and Cryptochrome (Cry1, Cry2), to activate their transcription during the daytime. The CRY-PER complexes inhibit CLOCK-BMAL1-driven transcription in a negative feedback loop to generate circadian rhythms. GO:1990514 5' transitive RNA interference biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990514 An RNA interference where the silencing signal spreads 5' along the target mRNA, outside of the initial target sequence. Typically involves the formation of secondary siRNAs formed when the initial mRNA target sequence functions as a template for 5' to 3' synthesis of new dsRNA. GO:1990515 3' transitive RNA interference biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990515 An RNA interference where the silencing signal spreads 3' along the target mRNA, outside of the initial target sequence. Typically involves the formation of secondary siRNAs formed when the initial mRNA target sequence functions as a template for 5' to 3' synthesis of new dsRNA. GO:1990520 separase-securin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990520 Cut1-2 complex A protein complex that includes separase (a protease which cleaves cohesin as part of chromosome separation) and securin, a protease inhibitor. Chromosome separation is inhibited until securin is degraded by the Anaphase Promoting Complex (APC). GO:1990521 m7G(5')pppN diphosphatase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990521 Binds to and increases the activity of m7G(5')pppN diphosphatase. GO:1990522 tail spike morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990522 WBbt:0008072|WBbt:0006979 The process in which the nematode tail spike is generated and organized. An example of this process is seen in C. elegans, where the tapered tail spike is formed during embryogenesis by a filamentous process that passes posteriorly through hyp10, the tail ventral hypodermis; the filamentous process is formed by a binucleate cell, the tail-spike cell, that subsequently undergoes programmed cell death. CHEBI:27765 (S)-3-hydroxy-3-methyl-2-oxopentanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27765 CHEBI:27767 3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27767 CHEBI:27760 L-selenocystathionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27760 CHEBI:27761 (S)-prunasin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27761 UBERON:0010371 ecto-epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010371 ectoderm-derived epithelium Epithelium composed of cells that develops from the ectoderm[FMA,modified]. CHEBI:27762 3-hydroxypropanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27762 UBERON:0010377 mesenchyme from somatopleure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010377 Mesenchyme that develops_from a somatopleure. UBERON:0010378 mesenchyme from splanchnopleure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010378 Mesenchyme that develops_from a splanchnopleure. UBERON:0010375 pancreas dorsal primordium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010375 dorsal pancreas UBERON:0010376 pancreas ventral primordium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010376 ventral pancreas UBERON:0010368 pulmonary lobule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010368 lobulus pulmonis The smallest anatomical unit of the lung, measuring 0.50 to 2.00 cm in diameter. Each lobule is composed of 4-8 terminal bronchioles and their distal alveolar ducts and sacs. The lobules are separated by fibrous interlobular septa. GO:1990527 Tec1p-Ste12p-Dig1p complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990527 A multiprotein complex that is involved in the transcriptional regulation of primarily filamentation genes, but also mating genes, in the yeast S. cerevisiae. GO:1990528 Rvs161p-Rvs167p complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990528 A protein complex that is involved in endocytosis in the yeast S. cerevisiae. GO:1990529 glycosylphosphatidylinositol-mannosyltransferase I complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990529 GPI-MT-I complex A protein complex that is involved in the transfer of the four mannoses in the GPI-anchor precursor. In yeast S. cerevisiae this complex consists of Pbn1p and Gpi14p and in rat this complex consists of PIG-X and PIG-M. GO:1990523 bone regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990523 The regrowth of bone following its loss or destruction. GO:1990524 INA complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990524 INAC A protein complex located in the inner membrane of mitochondria that is involved in the assembly of the peripheral (or stator) stalk of the mitochondrial proton-transporting ATP synthase (also known as the F1F0 ATP synthase). In budding yeast, this complex includes Ina22p and Ina17p. GO:1990525 BIR domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990525 Baculovirus Inhibitor of apoptosis protein Repeat domain binding Interacting selectively and non-covalently with a Baculovirus Inhibitor of apoptosis protein Repeat (BIR) domain. GO:1990526 Ste12p-Dig1p-Dig2p complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990526 A multiprotein complex that is involved in the transcription regulation of mating genes in the yeast S. cerevisiae. GO:1990530 Cdc50p-Drs2p complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990530 A protein complex that functions as a phospholipid-translocating P-Type ATPase. In budding yeast, this complex consists of Cdc50p and Drs2p proteins, and is involved in the trafficking of transport vesicles between the late Golgi and the early endosome. CHEBI:27735 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27735 GO:1990531 phospholipid-translocating ATPase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990531 Lem3p-Dnf1p complex|CDC50-DRS2 complex|DRS2-CDC50 complex|P4-ATPase complex|phospholipid flippase complex|Dnf1-Lem3 complex|Dnf2-Lem3 complex|APLT complex|DNF3-CRF1 complex|CRF1-DNF3 complex|aminophospholipid translocase complex|Lem3-Dnf1 complex A protein complex that functions as a phospholipid-translocating P-Type ATPase. GO:1990532 stress response to nickel ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990532 response to nickel toxicity|response to nickel ion stress|stress response to nickel Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a nickel ion stimulus. GO:1990533 Dom34-Hbs1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990533 Dom34:Hbs1 complex A protein complex consisting of one subunit known as Dom34 or Pelota that has similarity to translation termination factor eRF1, and another subunit, Hbs1, that is a GTPase with similarity to translation termination factor eRF3. The Dom34-Hbs1 complex has a role in cotranslational mRNA quality control by promoting ribosomal subunit dissociation and peptidyl-tRNA release when translation is stalled, facilitating no-go decay and nonstop decay. CHEBI:27731 N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27731 CHEBI:76706 EC 6.1.* (C-O bond-forming ligase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76706 CHEBI:27732 caffeine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27732 UBERON:0010362 endoskeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010362 replacement skeleton Skeletal subdivision that undergoes indirect development and includes elements that develop as a replacement or substitution of other elements or tissues. UBERON:0010363 endochondral element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010363 endochondral replacement element A skeletal element that has the potential to participate in endochondral ossification, and may participate in intramembranous ossification. UBERON:0010360 pharyngeal arch mesenchyme from head mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010360 branchial arch mesenchyme from head mesenchyme|arch mesenchyme from head mesenchyme|head mesenchyme derived arch mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a entire pharyngeal arch associated mesenchyme. CHEBI:76709 3-hydroxyicosanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76709 CHEBI:27730 D-isoleucine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27730 UBERON:0010366 conjunctival vasculature biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010366 conjunctival veins set|conjunctival veins|venae conjunctivales|set of conjunctival veins A vasculature that is part of a conjunctiva. UBERON:0010367 conjunctival vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010367 conjunctival blood vessel A vein that is part of a conjunctiva. UBERON:0010364 dermal skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010364 exoskeleton|desmoskeleton|dermoskeleton|dermal skeletal system Skeletal subdivision that undergoes direct development and includes elements that either develop in association with the basement membrane of the ectoderm or are homologous with such elements; includes dermatocranium, components of the appendicular skeleton, teeth and tooth-like elements of the oropharynx, and integumentary elements. UBERON:0010365 odontoid tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010365 dental tissue|odontogenic tissue|portion of substance of tooth|tooth hard tissue|tooth substance|tooth tissue|substance of tooth Skeletal tissue that is part of the exoskeleton and derived from an odontogenic papilla. UBERON:0010359 pharyngeal arch mesenchyme from neural crest biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010359 neural crest derived arch mesenchyme|arch mesenchyme from neural crest|branchial arch mesenchyme from neural crest Mesenchyme that develops_from a neural crest and is part of a entire pharyngeal arch associated mesenchyme. UBERON:0010358 arch of centrum of vertebra biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010358 arch of vertebra|vertebra arch|arcus vertebrae (vertebralis)|vertebral arch An arch-shaped structure of the vertebra that extends dorsally (neural arch) or ventrally (hemal arch) from the vertebral centrum GO:1990538 xylan O-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990538 Catalysis of the reaction: acetyl-CoA + a xylan= CoA + an acetylated xylan. GO:1990539 fructose import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990539 The directed movement of fructose substance from outside of a cell, across the plasma membrane and into the cytosol. GO:1990534 thermospermine oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990534 Catalysis of the reaction: S-methyl-5'-thioadenosine + thermospermine + H+ = S-adenosyl 3-(methylthio)propylamine + spermidine. GO:1990535 neuron projection maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990535 neuron process maintenance|axon maintenance|neuron protrusion maintenance|neurite maintenance|axon homeostasis|neuronal cell projection maintenance The organization process that preserves a neuron projection in a stable functional or structural state. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite. GO:1990536 phosphoenolpyruvate transmembrane import into Golgi lumen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990536 The directed movement of phosphoenolpyruvate into the Golgi lumen across the Golgi membrane. GO:1990537 mitotic spindle polar microtubule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990537 Any of the mitotic spindle microtubules that come from each pole and overlap at the spindle midzone. CHEBI:76713 EC 4.3.* (C-N lyase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76713 GO:1990541 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990541 GO:1990542 mitochondrial transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990542 The process in which a solute is transported from one side of a membrane to the other into, out of or within a mitochondrion. CHEBI:76714 EC 4.4.* (C-S lyase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76714 GO:1990543 mitochondrial S-adenosyl-L-methionine transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990543 The process in which S-adenosyl-L-methionine is transported across a mitochondrial membrane, into or out of the mitochondrion. CHEBI:27748 D-ribosylnicotinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27748 CHEBI:76711 EC 4.1.* (C-C lyase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76711 CHEBI:76712 EC 4.2.* (C-O lyase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76712 GO:1990544 mitochondrial ATP transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990544 The process in which ATP is transported across a mitochondrial membrane, into or out of the mitochondrion. CHEBI:27742 gibberellin A20 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27742 CHEBI:27744 glyphosate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27744 GO:1990540 mitochondrial manganese ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990540 The process in which a manganese ion is transported across a mitochondrial membrane, into or out of the mitochondrion. CHEBI:27740 gamma-carotene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27740 CHEBI:27741 3'-hydroxyflavonoid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27741 UBERON:0010355 ossification center biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010355 centrum ossificationis|centrum ossificationis|ossification centre|center of ossification The first step in ossification of the cartilage is that the cartilage cells, at the point where ossification is commencing and which is termed a ossification center, enlarge and arrange themselves in rows. The matrix in which they are imbedded increases in quantity, so that the cells become further separated from each other. A deposit of calcareous material now takes place in this matrix, between the rows of cells, so that they become separated from each other by longitudinal columns of calcified matrix, presenting a granular and opaque appearance. Here and there the matrix between two cells of the same row also becomes calcified, and transverse bars of calcified substance stretch across from one calcareous column to another. Thus there are longitudinal groups of the cartilage cells enclosed in oblong cavities, the walls of which are formed of calcified matrix which cuts off all nutrition from the cells; the cells, in consequence, atrophy, leaving spaces called the primary areolC&. UBERON:0010349 otic capsule pre-cartilage condensation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010349 otic capsule anlage A otic capsule endochondral element that is composed primarily of a pre-cartilage condensation. UBERON:0010347 6th arch mesenchyme from head mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010347 pharyngeal arch 6 mesenchyme from head mesenchyme|head mesenchyme derived arch 6 mesenchyme|branchial arch 6 mesenchyme from head mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 6th arch mesenchyme. CHEBI:13115 L-gulonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_13115 GO:1990549 mitochondrial NAD transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990549 The process in which NAD is transported across a mitochondrial membrane, into or out of the mitochondrion. GO:1990545 mitochondrial thiamine pyrophosphate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990545 The process in which thiamine pyrophosphate is transported across a mitochondrial membrane, into or out of the mitochondrion. GO:1990546 mitochondrial tricarboxylic acid transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990546 The process in which a tricarboxylic acid is transported across a mitochondrial membrane, into or out of the mitochondrion. CHEBI:76710 EC 4.* (lyase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76710 OIO:hasAlternativeId has_alternative_id biolink:OntologyClass go-plus http://www.geneontology.org/formats/oboInOwl#hasAlternativeId GO:1990547 mitochondrial phosphate ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990547 The process in which a phosphate ion is transported across a mitochondrial membrane, into or out of the mitochondrion. GO:1990548 mitochondrial FAD transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990548 The process in which FAD is transported across a mitochondrial membrane, into or out of the mitochondrion. CHEBI:27713 (5S)-5-amino-3-oxohexanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27713 CHEBI:76724 2-hydroxyoctadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76724 CHEBI:76725 EC 1.* (oxidoreductase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76725 CHEBI:27714 6-acetyl-2-amino-3,7,8,9-tetrahydropyrimido[4,5-b][1,4]diazepin-4-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27714 CHEBI:27715 3-chlorocatechol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27715 CHEBI:76722 2-hydroxybehenate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76722 CHEBI:76723 2-hydroxytetracosanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76723 CHEBI:76728 2-hydroxyhexacosanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76728 CHEBI:76729 EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76729 CHEBI:27711 precorrin-3B biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27711 CHEBI:76726 EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76726 CHEBI:76727 EC 1.2.* (oxidoreductase acting on donor aldehyde/oxo group) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76727 CHEBI:27717 gibberellin A1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27717 CHEBI:76735 EC 1.8.* (oxidoreductase acting on sulfur group of donors) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76735 CHEBI:76736 EC 1.9.* (oxidoreductase acting on donor heme group) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76736 CHEBI:76733 EC 1.6.* (oxidoreductase acting on NADH or NADPH) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76733 CHEBI:27726 6-chloro-1,3,5-triazine-2,4-diamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27726 CHEBI:27727 androstane-3,17-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27727 CHEBI:27721 trans-tetradec-2-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27721 CHEBI:76737 EC 1.10.* (oxidoreductase acting on diphenols and related substances as donors) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76737 CHEBI:76738 EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76738 CHEBI:76731 EC 1.5.* (oxidoreductase acting on donor CH-NH group) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76731 CHEBI:76732 2-hydroxyarachidate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76732 CHEBI:76730 EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76730 CHEBI:76744 EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76744 CHEBI:76748 EC 1.21.* (oxidoreductase acting on X-H and Y-H to form an X-Y bond) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76748 CHEBI:76740 EC 1.13.* [oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases)] inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76740 CHEBI:76741 EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76741 CHEBI:27702 (R)-norlaudanosoline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27702 CHEBI:27705 delta-carotene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27705 GO:1990500 eif4e-cup complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990500 IntAct:EBI-9674930 eukaryotic translation initiation factor 4E-cup complex A protein complex that causes translational repression in Drosophila. Prevents assembly of ribosomes at the mRNA by interfacing with a sequence-specific RNA-binding protein leading to recruitment of the CCR4 complex and consequently, reduction of the mRNA's poly(A) tail length. The complex is also required for dorso-ventral pattern formation in the embryo. UBERON:0010392 B cell domain biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010392 CHEBI:76759 EC 3.* (hydrolase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76759 CHEBI:27700 trans-3-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27700 UBERON:0010390 lumen of urethra biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010390 urethral lumen An organ cavity that is part of a urethra. CHEBI:27701 oxytetracycline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27701 UBERON:0010395 lymph node primary follicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010395 primary follicle of lymph node An unstimulated network of follicular dendritic cells and small resting B cells in the lymph node cortex. UBERON:0010393 T cell domain biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010393 UBERON:0010394 lymphocyte domain biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010394 UBERON:0010399 spleen trabecular artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010399 trabecular artery one of the branches of the splenic artery[MP] CHEBI:62111 6-O-acetyl-beta-D-glucose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62111 CHEBI:62117 6beta-hydroxyprogesterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62117 GO:1990509 PYM-mago-Y14 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990509 IntAct:EBI-9634190 wibg-mago-tsu complex|PYM-mago-RNA-binding protein 8A complex Protein complex involved in the disassembly of Mago-Y14 from the spliced mRNA during first round of translation, independently of the translational machinery. Conserved from fission yeast to humans. GO:1990505 mitotic DNA replication maintenance of fidelity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990505 mitotic DNA replication maintenance of fidelity|maintenance of fidelity involved in mitotic DNA replication|maintenance of fidelity involved in mitotic cell cycle DNA replication Any maintenance of fidelity that is involved in mitotic cell cycle DNA replication. GO:1990506 mitotic DNA-dependent DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990506 A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands during the mitotic cell cycle. GO:1990507 ATP-independent chaperone mediated protein folding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990507 The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone, and independent of ATP hydrolysis. GO:1990508 CKM complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990508 IntAct:EBI-2640924 SRB8-SRB11 complex|CDK8 kinase module|SRB8/9/10/11 complex Cyclin-dependent kinase complex which reversibly associates with the Mediator complex. In Saccharomyces cerevisiae it consists of SSN2, SSN3, SSN8 and SRB8. GO:1990501 exon-exon junction subcomplex mago-y14 biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990501 IntAct:EBI-9549962 MGN-RBM8A complex|mago-y14 complex|exon junction subcomplex MAGOH-Y14 Component of the core exon-exon-junction complex (EJC). Fairly conserved in eukaryotes; in Drosophila, consists of the Mago and Y14 (tsunagi) gene products. Important for coupling nuclear and cytoplasmic events in gene expression. Inhibits the ATPase activity of eIF4AIII (Q9VHS8) to ensure a stable association of the EJC core with the mRNA. CHEBI:27707 beta-D-Galp-(1->3)-D-GlcpNAc biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27707 GO:1990502 dense core granule maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990502 dense core vesicle maturation Steps required to transform a dense core granule generated at the trans-Golgi network into a fully formed and transmissible dense core granule. Dense core granule maturation proceeds through clathrin-mediated membrane remodeling events and is essential for efficient processing of cargo within dense core granules as well as for removing factors that might otherwise interfere with dense core granule trafficking and exocytosis. GO:1990503 dendritic lamellar body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990503 DLB A specialized secretory organelle found in neurons and associated with the formation of dendrodendritic gap junctions. CHEBI:27708 diethyl hydrogen phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27708 GO:1990504 dense core granule exocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990504 dense core vesicle exocytosis The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a membrane-bounced dense core granule by fusion of the granule with the plasma membrane of a cell in response to increased cytosolic calcium levels. GO:0001411 hyphal tip biolink:CellularComponent go-plus goslim_candida http://purl.obolibrary.org/obo/GO_0001411 The end, or tip, of a fungal hypha, where polarized growth occurs during hyphal elongation. GO:0050389 uronolactonase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050389 EC:3.1.1.19|RHEA:13337|MetaCyc:URONOLACTONASE-RXN glucuronolactonase activity|D-glucurono-6,2-lactone lactonohydrolase activity Catalysis of the reaction: D-glucurono-6,2-lactone + H2O = D-glucuronate. UBERON:0000978 leg biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000978 lower extremity|tetrapod leg The portion of the hindlimb that contains both the stylopod and zeugopod. UBERON:0000979 tibia biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000979 shinbone|shankbone The major preaxial endochondral bone in the posterior zeugopod[Phenoscape]. GO:0050387 urethanase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050387 MetaCyc:URETHANASE-RXN|KEGG_REACTION:R02359|EC:3.5.1.75|RHEA:21372 urethane hydrolase activity|urethane amidohydrolase (decarboxylating) Catalysis of the reaction: H(2)O + H(+) + urethane = CO(2) + ethanol + NH(4)(+). GO:0050388 uronate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050388 RHEA:22404|KEGG_REACTION:R01981|MetaCyc:URONATE-DEHYDROGENASE-RXN|EC:1.1.1.203 uronate: NAD-oxidoreductase activity|uronate:NAD+ 1-oxidoreductase activity|uronic acid dehydrogenase activity Catalysis of the reaction: D-galacturonate + H(2)O + NAD(+) = galactarate + 2 H(+) + NADH. UBERON:0000974 neck biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000974 neck (volume)|collum An organism subdivision that extends from the head to the pectoral girdle, encompassing the cervical vertebral column. UBERON:0000975 sternum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000975 breastbone|vertebrate sternum A midventral endochondral skeletal element which represents the origin site of the pectoral muscles[PHENOSCAPE:ad]. UBERON:0000976 humerus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000976 humeri|humerus bone|proximal metapterygial mesomere of pectoral fin|proximal metapterygial mesomere of pectoral appendage|mesomere 1 of pectoral appendage Paired endochondral long bone that extends between the pectoral girdle and the skeletal parts of the forelimb. [PHENOSCAPE:mah] UBERON:0000977 pleura biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000977 pleura|wall of pleural sac|pleural tissue The invaginated serous membrane that surrounds the lungs (the visceral portion) and lines the walls of the pleural cavity (parietal portion). GO:0001410 chlamydospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001410 chlamydospore development The process whose specific outcome is the progression of the chlamydospore over time, from its formation to the mature structure. A chlamydospores is a mitotic (asexual) one-celled spore, produced primarily for survival, not dispersal, originating endogenously and singly within part of a pre-existing cell and possessing an inner secondary and often thickened cell wall. An example of this is found in Candida albicans. CHEBI:37158 bromocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37158 UBERON:0000981 femur biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000981 os longissimum|femoral bone|os femorale|mesomere 1 of pevlic appendage|proximal metapterygial mesomere of pelvic fin|os femoris|proximal metapterygial mesomere of pelvic appendage|thigh bone Endochondral longbone connecting the pelvic girdle with posterior zeugopodium skeleton.[VSAO, modified]. GO:0050381 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050381 UBERON:0000982 skeletal joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000982 articular joint|joints|joint|articulation Anatomical cluster that consists of two or more adjacent skeletal structures, which may be interconnected by various types of tissue[VSAO]. CHEBI:52794 beta-L-aspartylhydroxamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52794 CHEBI:37153 EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37153 GO:0050382 uracil-5-carboxylate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050382 EC:4.1.1.66|KEGG_REACTION:R00973|MetaCyc:URACIL-5-CARBOXYLATE-DECARBOXYLASE-RXN|RHEA:17685 uracil-5-carboxylic acid decarboxylase activity|uracil-5-carboxylate carboxy-lyase activity|uracil-5-carboxylate carboxy-lyase (uracil-forming) Catalysis of the reaction: H(+) + uracil 5-carboxylate = CO(2) + uracil. UBERON:0000983 metatarsus region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000983 hindlimb equine cannon region|hind metapodium|hindlimb cannon region|metatarsal region|regio metatarsalis|metatarsus|metatarsal part of foot A metapodium region that is part of a pes. CHEBI:37151 1,3-dibromobenzene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37151 GO:0050380 undecaprenyl-diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050380 EC:3.6.1.27|KEGG_REACTION:R05627|RHEA:17069|MetaCyc:UNDECAPRENYL-DIPHOSPHATASE-RXN undecaprenyl-diphosphate phosphohydrolase activity|C55-isoprenyl pyrophosphatase activity|C55-isoprenyl diphosphatase activity|C(55)-isoprenyl pyrophosphatase activity|C(55)-isoprenyl diphosphatase activity|isoprenyl pyrophosphatase activity Catalysis of the reaction: all-trans-undecaprenyl diphosphate + H(2)O = all-trans-undecaprenyl phosphate + H(+) + phosphate. UBERON:0000984 imaginal disc-derived wing biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000984 adult metathoracic wing|wing|wing of thorax|adult mesothoracic wing|thorax wing|thoracic wing A flight organ of the adult external thorax that is derived from a dorsal mesothoracic disc. GO:0050385 ureidoglycolate lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050385 MetaCyc:UREIDOGLYCOLATE-LYASE-RXN|KEGG_REACTION:R00776|RHEA:11304|EC:4.3.2.3 ureidoglycolase activity|(S)-ureidoglycolate urea-lyase activity|ureidoglycolatase activity|(S)-ureidoglycolate urea-lyase (glyoxylate-forming)|ureidoglycolate hydrolase activity Catalysis of the reaction: (S)-ureidoglycolate = glyoxylate + urea. CHEBI:37156 maleate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37156 CHEBI:37157 3-oxodecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37157 GO:0050386 ureidosuccinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050386 EC:3.5.1.7|KEGG_REACTION:R00484|MetaCyc:UREIDOSUCCINASE-RXN|RHEA:14365 N-carbamoyl-L-aspartate amidohydrolase activity Catalysis of the reaction: N-carbamoyl-L-aspartate + H(2)O + 2 H(+) = L-aspartate + CO(2) + NH(4)(+). GO:0050383 uracil dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050383 EC:1.17.99.4|MetaCyc:URACIL-DEHYDROGENASE-RXN|RHEA:22752 Catalysis of the reaction: uracil + acceptor = barbiturate + reduced acceptor. CHEBI:37154 fumarate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37154 GO:0050384 urate-ribonucleotide phosphorylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050384 RHEA:13909|MetaCyc:URATE-RIBONUCLEOTIDE-PHOSPHORYLASE-RXN|EC:2.4.2.16|KEGG_REACTION:R02646 urate-ribonucleotide:phosphate alpha-D-ribosyltransferase activity|UAR phosphorylase activity|urate-ribonucleotide:phosphate D-ribosyltransferase activity Catalysis of the reaction: 3-(beta-D-ribofuranosyl)uric acid + phosphate = alpha-D-ribose 1-phosphate + H(+) + urate. CHEBI:37155 hydrogen butenedioate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37155 GO:0050398 wax-ester hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050398 RHEA:13577|MetaCyc:WAX-ESTER-HYDROLASE-RXN|EC:3.1.1.50 WEH|wax-ester acylhydrolase activity|jojoba wax esterase Catalysis of the reaction: a wax ester + H2O = a long-chain alcohol + a long-chain carboxylate. GO:0050399 xanthommatin reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050399 MetaCyc:XANTHOMMATIN-REDUCTASE-RXN|RHEA:13417|EC:1.3.1.41|KEGG_REACTION:R03787 5,12-dihydroxanthommatin:NAD+ oxidoreductase activity Catalysis of the reaction: 5,12-dihydroxanthommatin + NAD(+) = H(+) + NADH + xanthommatin. UBERON:0000963 head sensillum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000963 UBERON:0000964 cornea biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000964 corneas|cornea of camera-type eye|tunica cornea the transparent anterior portion of the fibrous coat of the eye that serves as the chief refractory structure UBERON:0000965 lens of camera-type eye biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000965 crystalline lens|eye lens|camera-type eye lens|lenses|lens crystallina|lens|ocular lens Transparent part of camera-type eye that helps to refract light to be focused on the retina. UBERON:0000966 retina biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000966 retina of camera-type eye|inner layer of eyeball|tunica interna of eyeball|retinas|Netzhaut The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates. GO:0050392 vicianin beta-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050392 RHEA:14041|MetaCyc:VICIANIN-BETA-GLUCOSIDASE-RXN|KEGG_REACTION:R03642|EC:3.2.1.119 (R)-vicianin beta-D-glucohydrolase activity|vicianin hydrolase activity|vicianin b-glucosidase activity Catalysis of the reaction: (R)-vicianin + H(2)O = mandelonitrile + vicianose. UBERON:0000970 eye biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000970 light-detecting organ|visual apparatus An organ that detects light. CHEBI:52782 O-acyl carbohydrate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52782 CHEBI:37163 glucan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37163 GO:0050393 vinylacetyl-CoA delta-isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050393 RHEA:10572|EC:5.3.3.3|KEGG_REACTION:R03031|MetaCyc:VINYLACETYL-COA-DELTA-ISOMERASE-RXN vinylacetyl-CoA D-isomerase activity|vinylacetyl-CoA delta3-delta2-isomerase activity|vinylacetyl coenzyme A isomerase activity|delta3-cis-delta2-trans-enoyl-CoA isomerase|vinylacetyl coenzyme A delta-isomerase activity Catalysis of the reaction: vinylacetyl-CoA = crotonoyl-CoA. CHEBI:37164 homopolysaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37164 UBERON:0000971 ommatidium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000971 omatidium|omatidia The smallest morphological and functional unit of the compound eye that consists of a usually limited and often constant number of rhabdomeric photoreceptor cells, cornea-secreting epithelial cells, and interommatidial pigment cells, and may additionally contain crystalline cone cells. GO:0050390 valine decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050390 UM-BBD_reactionID:r1052|MetaCyc:VALINE-DECARBOXYLASE-RXN|EC:4.1.1.14|KEGG_REACTION:R01437|RHEA:18989 leucine decarboxylase activity|L-valine carboxy-lyase activity|L-valine carboxy-lyase (2-methylpropanamine-forming) Catalysis of the reaction: L-valine + H(+) = 2-methylpropanamine + CO(2). UBERON:0000972 antenna biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000972 feeler The paired, usually multiple jointed, sensory organs articulating on the procephalic region of the head capsule; its highly versatile sensory structures are capable to detect the various environmental stimuli. In the context of Drosophila refers to they are the most anterior segmented sensory appendage of the head. GO:0050391 valine dehydrogenase (NADP) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050391 EC:1.4.1.8|MetaCyc:VALINE-DEHYDROGENASE-NADP+-RXN|RHEA:11156 L-valine:NADP+ oxidoreductase (deaminating)|valine dehydrogenase (NADP+) activity|valine dehydrogenase (nicotinanide adenine dinucleotide phosphate) Catalysis of the reaction: L-valine + H2O + NADP+ = 3-methyl-2-oxobutanoate + NH3 + NADPH. CHEBI:37162 trans-2-dodecenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37162 CHEBI:52785 2-(E)-O-feruloyl-D-galactaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52785 CHEBI:13170 Ser-tRNA(Sec) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_13170 GO:0050396 vomifoliol 4'-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050396 EC:1.1.1.221|RHEA:22804|MetaCyc:VOMIFOLIOL-4-DEHYDROGENASE-RXN|KEGG_REACTION:R04412 vomifoliol:NAD+ 4'-oxidoreductase activity Catalysis of the reaction: (6S,9R)-6-hydroxy-3-oxo-alpha-ionol + NAD(+) = (6S)-6-hydroxy-3-oxo-alpha-ionone + H(+) + NADH. GO:0050397 Watasenia-luciferin 2-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050397 MetaCyc:WATASEMIA-LUCIFERIN-2-MONOOXYGENASE-RXN|RHEA:18057|EC:1.13.12.8 luciferase activity|Watasenia-luciferin:oxygen 2-oxidoreductase (decarboxylating)|Watasenia-type luciferase activity Catalysis of the reaction: Watasenia luciferin + O2 = oxidized Watasenia luciferin + CO2 + light. GO:0050394 viomycin kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050394 EC:2.7.1.103|MetaCyc:VIOMYCIN-KINASE-RXN|RHEA:20509 viomycin phosphotransferase activity|ATP:viomycin O-phosphotransferase activity|capreomycin phosphotransferase activity Catalysis of the reaction: ATP + viomycin = ADP + O-phosphoviomycin. CHEBI:37165 galactan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37165 CHEBI:13172 keto-L-sorbose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_13172 GO:0050395 vitexin beta-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050395 EC:2.4.1.105|MetaCyc:VITEXIN-BETA-GLUCOSYLTRANSFERASE-RXN|RHEA:21956|KEGG_REACTION:R03565 UDP-glucose:vitexin 2''-O-beta-D-glucosyltransferase activity|vitexin b-glucosyltransferase activity|uridine diphosphoglucose-vitexin 2''-glucosyltransferase activity|UDPglucose:vitexin 2''-O-beta-D-glucosyltransferase activity Catalysis of the reaction: UDP-D-glucose + vitexin = H(+) + UDP + vitexin 2''-O-beta-D-glucoside. CHEBI:13173 L-tagatose 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_13173 CHEBI:37166 xylan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37166 UBERON:0000956 cerebral cortex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000956 cortex cerebri|cortex cerebralis|cortical plate (CTXpl)|cortical plate (areas)|cortex of cerebral hemisphere|pallium of the brain|brain cortex The thin layer of gray matter on the surface of the cerebral hemisphere that develops from the telencephalon. It consists of the neocortex (6 layered cortex or isocortex), the hippocampal formation and the olfactory cortex. UBERON:0000957 lamina biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000957 laminar tissue Any thin layer or plate. UBERON:0000958 medulla of organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000958 medulla Middle part of an organ, surrounded by the cortex. UBERON:0000959 optic chiasma biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000959 decussation of optic nerve fibers|optic chiasm (Rufus of Ephesus)|chiasma nervorum opticorum|chiasma opticum|optic chiasm|chiasma A decussation of the diencephalon where the fibers of the optic nerve cross CHEBI:52775 UDP-N-acetyl-2-amino-2-deoxy-D-glucuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52775 UBERON:0000955 brain biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000955 suprasegmental structures|synganglion|suprasegmental levels of nervous system|encephalon|the brain The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as jellyfish and starfish have a decentralized nervous system without a brain, while sponges lack any nervous system at all. In vertebrates, the brain is located in the head, protected by the skull and close to the primary sensory apparatus of vision, hearing, balance, taste, and smell[WP]. UBERON:0000961 thoracic ganglion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000961 thoracic paravertebral ganglion|thoracic sympathetic ganglion|ganglion of thorax|ganglion thoracicum splanchnicum|thorax ganglion|thoracic splanchnic ganglion The thoracic ganglia are paravertebral ganglia. The thoracic portion of the sympathetic trunk typically has 12 thoracic ganglia. Emerging from the ganglia are thoracic splancic nerves (the cardiopulmonary, the greater, lesser, and least splanchic nerves) that help provide sympathetic innervation to abdominal structures. Also, the ganglia of the thoracic sympathetic trunk have both white and gray rami communicantes. The white rami carry sympathetic fibers arising in the spinal cord into the sympathetic trunk. [WP,unvetted]. CHEBI:52773 alpha-D-glucosiduronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52773 UBERON:0000962 nerve of cervical vertebra biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000962 cervical spinal nerve|cervical nerve tree|nervus cervicalis|cervical nerve The cervical nerves are the spinal nerves from the cervical vertebrae. Although there are seven cervical vertebrae (C1-C7), there are eight cervical nerves (C1-C8). All nerves except C8 emerge above their corresponding vertebrae, while the C8 nerve emerges below the C7 vertebra. (In the other portions of the spine, the nerve emerges below the vertebra with the same name. Dorsal (posterior) distribution includes the greater occipital (C2) and third occipital (C3). Ventral (anterior) distribution includes the cervical plexus (C1-C4) and brachial plexus (C5-C8) [WP,unvetted]. GO:0001400 mating projection base biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001400 base of shmoo tip|conjugation tube base The region where the mating projection meets the bulk of the cell, in unicellular fungi exposed to mating pheromone. UBERON:0000945 stomach biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000945 stomach chamber|ventriculus|gaster|anterior intestine|mesenteron An expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ. A stomach is lined, in whole or in part by a glandular epithelium. UBERON:0000946 cardial valve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000946 heart valve|stomodaeal valve|valve of heart|cardiac valve|heart valves|heart valve|valvule A membranous fold of the heart that prevents reflux of fluid GO:0001401 SAM complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001401 mitochondrial sorting and assembly machinery complex|TOB complex A large complex of the mitochondrial outer membrane that mediates sorting of some imported proteins to the outer membrane and their assembly in the membrane; functions after import of incoming proteins by the mitochondrial outer membrane translocase complex. UBERON:0000947 aorta biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000947 dorsal aorta|arteria maxima|trunk of systemic arterial tree|trunk of aortic tree The main trunk of the systemic arterial system that carries blood from the heart to all the organs and other structures of the body, bringing oxygenated blood to all parts of the body in the systemic circulation GO:0001402 signal transduction involved in filamentous growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001402 MAPKKK cascade (pseudohyphal growth)|signal transduction during filamentous growth Relaying of environmental signals promoting filamentous growth. UBERON:0000948 heart biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000948 vertebrate heart|cardium|chambered heart|branchial heart|Herz@de A myogenic muscular circulatory organ found in the vertebrate cardiovascular system composed of chambers of cardiac muscle. It is the primary circulatory organ. GO:0001403 invasive growth in response to glucose limitation biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0001403 colony morphology A growth pattern exhibited by budding haploid cells under certain growth conditions, in which cells retain the typical axial budding pattern of haploids, but become elongated and fail to separate after division; during growth on a solid substrate, this results in penetration of cells into the agar medium. An example of this process is found in Saccharomyces cerevisiae. UBERON:0000941 cranial nerve II biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000941 nerve II|2n|optic nerve|optic nerve [II]|optic|cranial II|nervus opticus|nervus opticus [II]|CN-II|optic II nerve|02 optic nerve|second cranial nerve|optic II Cranial nerve fiber tract which is comprised of retinal ganglion cell axons running posterior medially towards the optic chiasm, at which some of the axons cross the midline and after which the structure is termed the optic tract. Transmits visual information from the retina to the brain[ZFA]. UBERON:0000949 endocrine system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000949 endocrine system|systema endocrinum|endocrine glandular system Anatomical system that consists of the glands and parts of glands that produce endocrine secretions and help to integrate and control bodily metabolic activity. CHEBI:37149 bromobenzenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37149 CHEBI:37147 dibromobenzene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37147 CHEBI:37148 bromoarene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37148 CHEBI:37141 organobromine compound biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37141 GO:0001408 guanine nucleotide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001408 The directed movement of guanine nucleotides, GTP, GDP, and/or GMP, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:13197 ribonucleoside 3'-monophosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_13197 CHEBI:37142 organoiodine compound biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37142 GO:0001409 guanine nucleotide transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001409 Enables the transfer of guanine nucleotides (GMP, GDP, and GTP) from one side of a membrane to the other. UBERON:0000951 rotator muscle of the vertebral column biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000951 rotator muscle Any of a number of short transversospinal muscles chiefly developed in cervical, lumbar, and thoracic regions, arising from the transverse process of one vertebra and inserted into the root of the spinous process of the next two or three vertebrae above, with nerve supply from the dorsal branches of the spinal nerve, and whose actions rotate the vertebral column. GO:0001404 obsolete invasive growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001404 tissue invasion|invasive growth OBSOLETE. Growth of a pathogenic organism that results in penetration into cells or tissues of the host organism. This often (but not necessarily) includes a filamentous growth form, and also can include secretion of proteases and lipases to break down host tissue. CHEBI:13193 hydrogen acceptor biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_13193 GO:0001405 PAM complex, Tim23 associated import motor biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001405 mitochondrial import motor|pre-sequence translocase-associated import motor|PAM complex|presequence translocase-associated import motor Protein complex located on the matrix side of the mitochondrial inner membrane and associated with the TIM23 mitochondrial import inner membrane translocase complex (GO:0005744); ATPase motor activity to drive import of proteins into the mitochondrial matrix. CHEBI:37146 molybdopterin dinucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37146 GO:0001406 glycerophosphodiester transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001406 Enables the transfer of glycerophosphodiesters from one side of a membrane to the other. Glycerophosphodiesters are small molecules composed of glycerol-3-phosphate and an alcohol, for example, glycerophosphoinositol. CHEBI:37143 organofluorine compound biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37143 GO:0001407 glycerophosphodiester transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001407 The process in which a glycerophosphodiester is transported across a membrane. Glycerophosphodiesters are small molecules composed of glycerol-3-phosphate and an alcohol, for example, glycerophosphoinositol. CHEBI:27798 nitrobenzene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27798 UBERON:0010341 1st arch mesenchyme from head mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010341 mesenchyme derived from head mesoderm of mesenchyme of 1st arch Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 1st arch mesenchyme. UBERON:0010344 3rd arch mesenchyme from head mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010344 pharyngeal arch 3 mesenchyme from head mesenchyme|head mesenchyme derived arch 3 mesenchyme|mesenchyme derived from head mesoderm of mesenchyme of 3rd arch|branchial arch 3 mesenchyme from head mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 3rd arch mesenchyme. UBERON:0010345 4th arch mesenchyme from head mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010345 pharyngeal arch 4 mesenchyme from head mesenchyme|head mesenchyme derived arch 4 mesenchyme|mesenchyme derived from head mesoderm of mesenchyme of 4th arch|branchial arch 4 mesenchyme from head mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 4th arch mesenchyme. UBERON:0010343 2nd arch mesenchyme from head mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010343 pharyngeal arch 2 mesenchyme from head mesenchyme|head mesenchyme derived arch 2 mesenchyme|mesenchyme derived from head mesoderm of mesenchyme of 2nd arch|branchial arch 2 mesenchyme from head mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 2nd arch mesenchyme. UBERON:0010337 mandibular process mesenchyme from head mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010337 Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a mandibular process mesenchyme. UBERON:0010338 1st arch maxillary mesenchyme from head mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010338 Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 1st arch maxillary mesenchyme. UBERON:0010335 maxillary process mesenchyme from head mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010335 Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a maxillary process mesenchyme. UBERON:0010336 mandibular process mesenchyme from neural crest biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010336 Mesenchyme that develops_from a neural crest and is part of a mandibular process mesenchyme. UBERON:0010339 1st arch mandibular mesenchyme from head mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010339 Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 1st arch mandibular mesenchyme. CHEBI:52742 D-ribofuranose 5-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52742 UBERON:0010330 eyelid mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010330 Mesenchyme that is part of a developing eyelid. UBERON:0010333 extraembryonic membrane mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010333 Mesenchyme that is part of a extraembryonic membrane. UBERON:0010334 maxillary process mesenchyme from neural crest biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010334 Mesenchyme that develops_from a neural crest and is part of a maxillary process mesenchyme. UBERON:0010332 epithelium of handplate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010332 handplate epithelium An epithelium that is part of a handplate. CHEBI:37127 3-methylbut-2-enoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37127 CHEBI:37128 caesium molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37128 CHEBI:37125 5-hydroxy monocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37125 UBERON:0010328 limb bud mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010328 Mesenchyme that is part of a limb bud. UBERON:0010329 paired limb/fin bud mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010329 Mesenchyme that is part of a limb/fin bud. CHEBI:37120 guanosine 3'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37120 CHEBI:37123 nucleoside bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37123 CHEBI:37124 guanosine bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37124 CHEBI:37121 guanosine 5'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37121 UBERON:0000996 vagina biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000996 distal oviductal region|vaginae|distal portion of oviduct A fibromuscular tubular tract leading from the uterus to the exterior of the body in female placental mammals and marsupials, or to the cloaca in female birds, monotremes, and some reptiles[WP]. CHEBI:52731 5-alkatrienylresorcinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52731 CHEBI:27775 P(1),P(3)-bis(5'-adenosyl) triphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27775 UBERON:0000997 mammalian vulva biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000997 vulva|puboperineal region|skin of vulva|mammalian vulva|pudendum|female pudendum|pudendum femininum|skin of female pudendum|pudendum femininum|pudendum muliebre external genital organs of the female mammal[WP]. UBERON:0000998 seminal vesicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000998 vesicular seminalis|vesicular glands|vesicular gland|gonecyst|seminal gland|vesiculae seminales|vas efferens|glandula vesiculosa|glandula seminalis|vesiculæ seminales|vesicula seminalis Either of a pair of glandular pouches that lie one on either side of the male reproductive tract posterolateral to the urinary bladder and in the human male secrete a sugar- and protein-containing fluid into the ejaculatory duct. UBERON:0000999 ejaculatory duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000999 ductus ejaculatorii|ductus ejaculatorius|ductus ejaculatorii The Ejaculatory ducts (ductus ejaculatorii) are paired structures in male anatomy, about 2 cm in length. Each ejaculatory duct is formed by the union of the vas deferens with the duct of the seminal vesicle. They pass through the prostate, and empty into the urethra at the Colliculus seminalis. During ejaculation, semen passes through the ducts and exits the body via the penis[WP,unvetted]. CHEBI:27771 16alpha-hydroxydehydroepiandrosterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27771 CHEBI:27772 4-chlorocatechol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27772 CHEBI:27773 cis-3-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27773 UBERON:0010323 cranial skeletal system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010323 osteocranium|cranium|cranial skeleton Skeletal subdivision of the head including skull (cranium plus mandible), pharyngeal and/or hyoid apparatus. UBERON:0010321 skeletal element of eye region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010321 skeletal element of orbital region|eye skeleton|ocular skeleton A skeletal element that is part of a orbital region. CHEBI:350546 serotonin(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_350546 CHEBI:27770 nonanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27770 UBERON:0010316 germ layer / neural crest biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010316 UBERON:0010313 neural crest-derived structure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010313 An anatomical structure that develops from the neural crest. UBERON:0010314 structure with developmental contribution from neural crest biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010314 An anatomical structure that has some part that develops from the neural crest. CHEBI:13166 Sec-tRNA(Sec) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_13166 UBERON:0000989 penis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000989 phallus|penes A intromittent organ in certain biologically male organisms. In placental mammals, this also serves as the organ of urination CHEBI:52726 proteasome inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52726 CHEBI:27786 hydroxocobalamin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27786 UBERON:0000985 axillary vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000985 subcostal vein|vena axillaris Vein that drains the axilla CHEBI:27787 15-cis-phytoene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27787 UBERON:0000987 haltere biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000987 balancer organ The capitate stalk on both sides of the thorax having developed from the dorsal metathoracic wing-buds, it is freely movable and capable of vibration, representing the hind wing of Diptera; used for flight balance. UBERON:0000988 pons biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000988 pons Varolii|pons cerebri|pons of Varolius The part of the central nervous system lying between the medulla oblongata and the midbrain, ventral to the cerebellum. CHEBI:27789 1,2-dichloroethane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27789 CHEBI:27784 gentamycin C1a biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27784 UBERON:0010312 immature eye biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010312 future eye Developing anatomical structure that develops into the eyeball and associated structures. CHEBI:27780 detergent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27780 UBERON:0010310 nictitating membrane lamina biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010310 cartilago intercipiens|nictitating membrane cartilage thin cartilage element that stiffens the nictitating membrane. CHEBI:27781 myristoleic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27781 CHEBI:37105 2-aminopteridin-4(1H)-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37105 UBERON:0010304 non-keratinized stratified squamous epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010304 stratified squamous nonkeratinizing epithelium|nonkeratinizing stratified squamous epithelium|stratified squamous non-keratinized epithelium|epithelium stratificatum squamosum noncornificatum Stratified squamous epithelium is a stratified squamous epithelium, the cells of which synthesizes but does not accumulate keratin. Examples: epithelium of vagina, epithelium of wall of esophagus. UBERON:0010305 subdivision of conjunctiva biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010305 conjunctiva region|region of conjunctiva One of the three major regions of the conjunctiva. UBERON:0010302 amnioserosa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010302 amnion-serosa A single extraembryonic epithelium, which closes the germband dorsally. UBERON:0010303 extraembryonic epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010303 extra-embryonic epithelium An epithelium that is part of a extraembryonic structure. CHEBI:37107 7-methyl-3-oxooctanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37107 CHEBI:37108 7-methyloctanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37108 UBERON:0000992 ovary biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000992 gonada of female organism reproductive system|female gonad|female organism genitalia gonada|reproductive system of female organism gonad|gonad of female organism genitalia|gonad of female reproductive system|gonad of genitalia of female organism|ovum-producing ovary|reproductive system of female organism gonada|female organism genitalia gonad|gonada of reproductive system of female organism|female reproductive system gonad|genitalia of female organism gonad|gonad of female organism reproductive system|ovarium|gonada of female organism genitalia|female organism reproductive system gonad|gonada of genitalia of female organism|gonada of female reproductive system|female organism reproductive system gonada|animal ovary|gonad of reproductive system of female organism|ovaries|genitalia of female organism gonada|female reproductive system gonada the gonad of a female organism which contains germ cells UBERON:0000993 oviduct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000993 tuba uterinae|uterine tube|tubular parts of female reproductive system|tuba uterina|oviducts|female reproductive tracts|ovarian tube|ovarian duct A tube or collection of tubes in an animal from the ovaries to the outside of the body. UBERON:0000994 spermathecum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000994 receptaculum seminis|spermathecae|spermatheca|seminal receptacle An organ of the female reproductive tract that functions to receive and store sperm from the male, and can sometimes be the site of fertilization when the oocytes are ready. UBERON:0000995 uterus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000995 the female muscular organ of gestation in which the developing embryo or fetus is nourished until birth CHEBI:37102 nucleoside pentaphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37102 UBERON:0000990 reproductive system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000990 Geschlechtsorgan|genital tract|reproductive tract|animal reproductive system|organa genitalia|reproductive tissue|genital system|genitalia|systemata genitalia Anatomical system that has as its parts the organs concerned with reproduction. UBERON:0000991 gonad biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000991 gonads|gonada Reproductive organ that produces and releases eggs (ovary) or sperm (testis). CHEBI:37100 (S)-3-hydroxyoctanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37100 GO:0050301 streptomycin-6-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050301 MetaCyc:STREPTOMYCIN-6-PHOSPHATASE-RXN|EC:3.1.3.39|KEGG_REACTION:R02228|RHEA:10688 streptomycin-6-phosphate phosphohydrolase activity|streptomycin-6-P phosphohydrolase activity|streptomycin 6-phosphate phosphohydrolase activity|streptomycin 6-phosphate phosphatase activity Catalysis of the reaction: H(2)O + streptomycin 6-phosphate = phosphate + streptomycin. GO:0050302 indole-3-acetaldehyde oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050302 KEGG_REACTION:R02681|EC:1.2.3.7|RHEA:16277|MetaCyc:INDOLE-3-ACETALDEHYDE-OXIDASE-RXN (indol-3-yl)acetaldehyde:oxygen oxidoreductase activity|AO1|IAAld oxidase activity|IAA oxidase activity|indole-3-acetaldehyde:oxygen oxidoreductase activity|indoleacetaldehyde oxidase activity Catalysis of the reaction: (indol-3-yl)acetaldehyde + H(2)O + O(2) = (indol-3-yl)acetate + H(2)O(2) + H(+). GO:0050300 aminoglycoside 6-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050300 EC:2.7.1.72|KEGG_REACTION:R02225|RHEA:22268|MetaCyc:STREPTOMYCIN-6-KINASE-RXN streptidine kinase activity|streptomycin 6-O-phosphotransferase activity|streptomycin 6-phosphotransferase activity|SM 6-kinase activity|streptomycin 6-kinase activity|ATP:streptomycin 6-phosphotransferase activity|APH(6) activity|streptidine kinase (phosphorylating)|streptomycin 6-kinase (phosphorylating) Catalysis of the reaction: ATP + streptomycin = ADP + 2 H(+) + streptomycin 6-phosphate. GO:0050305 strombine dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050305 RHEA:14061|MetaCyc:STROMBINE-DEHYDROGENASE-RXN|KEGG_REACTION:R00368|EC:1.5.1.22 strombine[N-(carboxymethyl)-D-alanine]dehydrogenase activity|N-(carboxymethyl)-D-alanine: NAD+ oxidoreductase activity|N-(carboxymethyl)-D-alanine:NAD+ oxidoreductase (glycine-forming) Catalysis of the reaction: N-(carboxymethyl)-D-alanine + H(2)O + NAD(+) = glycine + H(+) + NADH + pyruvate. GO:0050306 sucrose 1F-fructosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050306 RHEA:23312|MetaCyc:SUCROSE-1F-FRUCTOSYLTRANSFERASE-RXN|EC:2.4.1.99 sucrose-sucrose 1-fructosyltransferase activity|sucrose:sucrose 1'-beta-D-fructosyltransferase activity|sucrose:sucrose 1(F)-beta-D-fructosyltransferase activity|sucrose:sucrose 1-fructosyltransferase activity|sucrose:sucrose fructosyltransferase activity|SST activity|sucrose 1(F)-fructosyltransferase activity|sucrose:sucrose 1F-beta-D-fructosyltransferase activity Catalysis of the reaction: 2 sucrose = D-glucose + 1F-beta-D-fructosylsucrose. GO:0050303 lysine 6-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050303 EC:1.4.1.18|MetaCyc:LYSINE-6-DEHYDROGENASE-RXN|RHEA:12408|MetaCyc:PWY-5314 L-lysine:NAD+ 6-oxidoreductase (deaminating)|L-lysine epsilon-dehydrogenase activity|LysDH activity|L-lysine 6-dehydrogenase activity Catalysis of the reaction: H2O + NAD+ + L-lysine = NH3 + NADH + allysine. CHEBI:86051 O-octanoyl-D-carnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86051 GO:0050304 nitrous-oxide reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050304 EC:1.7.2.4|MetaCyc:RXN-12130|KEGG_REACTION:R02804|RHEA:43108 N2O reductase activity|nitrogen:acceptor oxidoreductase (N2O-forming)|nitrous oxide reductase activity|nitrogen:(acceptor) oxidoreductase (N2O-forming) Catalysis of the reaction: H(2)O + 2 cytochrome c + nitrogen = 2 reduced cytochrome c + nitrous oxide. CHEBI:62081 1,1-diunsubstituted alkanesulfonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62081 CL:0000006 neuronal receptor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000006 neuronal receptor cell (sensu Animalia) CHEBI:86053 18-hydroxyoleoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86053 GO:0050309 sugar-terminal-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050309 EC:3.1.3.58 xylitol-5-phosphatase activity|sugar-omega-phosphate phosphohydrolase activity Catalysis of the reaction: H2O + sugar phosphorylated on the terminal carbon = a sugar + phosphate. CL:0000007 early embryonic cell (metazoa) biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000007 A cell found in the embryo before the formation of all the gem layers is complete. PR:000024025 methyl-accepting chemotaxis protein IV biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000024025 tap|MCP-IV|dipeptide chemoreceptor protein A protein that is a translation product of the Escherichia coli K-12 tap gene or a 1:1 ortholog thereof. GO:0050307 sucrose-phosphate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050307 KEGG_REACTION:R06211|RHEA:19289|MetaCyc:SUCROSE-PHOSPHATASE-RXN|KEGG_REACTION:R00805|EC:3.1.3.24 sucrose-6F-phosphate phosphohydrolase activity|sucrose-phosphate phosphohydrolase activity Catalysis of the reaction: sucrose 6F-phosphate + H2O = sucrose + phosphate. CL:0000008 migratory cranial neural crest cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000008 Cell that is part of the migratory cranial neural crest population. Migratory cranial neural crest cells develop from premigratory cranial neural crest cells and have undergone epithelial to mesenchymal transition and delamination. CHEBI:86055 ethyl hexanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86055 GO:0050308 sugar-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050308 MetaCyc:SUGAR-PHOSPHATASE-RXN|KEGG_REACTION:R00804|EC:3.1.3.23 sugar-phosphate phosphohydrolase activity|sugar-phosphate phosphatase activity Catalysis of the reaction: sugar phosphate + H2O = sugar + phosphate. CHEBI:62089 EC 1.4.7.1 [glutamate synthase (ferredoxin)] inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62089 CL:0000000 cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000000 A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane. CL:0000003 native cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000003 cell in vivo A cell that is found in a natural setting, which includes multicellular organism cells 'in vivo' (i.e. part of an organism), and unicellular organisms 'in environment' (i.e. part of a natural environment). CL:0000005 fibroblast neural crest derived biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000005 Any fibroblast that is deriived from the neural crest. GO:0050312 sulfoacetaldehyde lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050312 EC:4.4.1.- sulphoacetaldehyde lyase activity Catalysis of the reaction: 2-sulfoacetaldehyde + H2O = acetate + sulfite. GO:0050313 sulfur dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050313 MetaCyc:FESGSHTHIO-RXN|RHEA:12981|Reactome:R-HSA-1614605|EC:1.13.11.18 sulfur oxygenase activity|S-sulfanylglutathione:oxygen oxidoreductase activity|sulfur:oxygen oxidoreductase activity|sulphur dioxygenase activity Catalysis of the reaction: sulfur + O2 + H2O = sulfite. CHEBI:62090 germacra-1(10),4,11(13)-trien-12-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62090 GO:0050310 sulfite dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050310 MetaCyc:SULFITE-DEHYDROGENASE-RXN|EC:1.8.2.1|RHEA:14281 sulfite:ferricytochrome-c oxidoreductase activity|sulfite cytochrome c reductase activity|sulphite dehydrogenase activity|sulfite-cytochrome c oxidoreductase activity Catalysis of the reaction: sulfite + 2 ferricytochrome c + H2O = sulfate + 2 ferrocytochrome c. GO:0050311 sulfite reductase (ferredoxin) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050311 MetaCyc:SULFITE-REDUCTASE-FERREDOXIN-RXN|EC:1.8.7.1|RHEA:23132 ferredoxin-sulfite reductase activity|sulphite reductase (ferredoxin) activity|hydrogen-sulfide:ferredoxin oxidoreductase activity Catalysis of the reaction: hydrogen sulfide + 3 oxidized ferredoxin + 3 H2O = sulfite + 3 reduced ferredoxin. GO:0050316 T2-induced deoxynucleotide kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050316 MetaCyc:GMKALT-RXN|RHEA:12697|EC:2.7.4.12 ATP:(d)NMP phosphotransferase activity Catalysis of the reactions: ATP + dGMP = ADP + dGDP, and ATP + dTMP = ADP + dTDP. GO:0050317 tagatose kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050317 KEGG_REACTION:R02927|RHEA:15513|EC:2.7.1.101|MetaCyc:TAGATOSE-KINASE-RXN tagatose 6-phosphate kinase (phosphorylating)|D-tagatose 6-phosphate kinase activity|ATP:D-tagatose 6-phosphotransferase activity Catalysis of the reaction: D-tagatose + ATP = D-tagatose 6-phosphate + ADP + 2 H(+). GO:0050314 sym-norspermidine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050314 EC:2.5.1.23|RHEA:23244|MetaCyc:SYM-NORSPERMIDINE-SYNTHASE-RXN|KEGG_REACTION:R03271 S-adenosylmethioninamine:propane-1,3-diamine 3-aminopropyltransferase activity Catalysis of the reaction: 1,3-diaminopropane + S-adenosylmethioninamine = S-methyl-5'-thioadenosine + bis(3-aminopropyl)amine + H(+). CHEBI:86040 3-hydroxyoctanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86040 CHEBI:62091 germacra-1(10),4,11(13)-trien-12-al biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62091 CHEBI:86041 3-hydroxydecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86041 GO:0050315 synephrine dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050315 EC:4.2.1.88|KEGG_REACTION:R03359|RHEA:32203|MetaCyc:SYNEPHRINE-DEHYDRATASE-RXN 1-(4-hydroxyphenyl)-2-(methylamino)ethanol hydro-lyase (methylamine-forming) Catalysis of the reaction: synephrine = (4-hydroxyphenyl)acetaldehyde + methylammonium. CHEBI:86042 2-methyl-3-oxopalmitoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86042 CL:0000017 spermatocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000017 A male germ cell that develops from spermatogonia. The euploid primary spermatocytes undergo meiosis and give rise to the haploid secondary spermatocytes which in turn give rise to spermatids. CL:0000018 spermatid biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000018 nematoblast A male germ cell that develops from the haploid secondary spermatocytes. Without further division, spermatids undergo structural changes and give rise to spermatozoa. CHEBI:86043 O-acyl-D-carnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86043 GO:0050318 tannase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050318 EC:3.1.1.20|MetaCyc:TANNASE-RXN|KEGG_REACTION:R00053|RHEA:16365 tannin acylhydrolase activity|tannase S|tannin acetylhydrolase activity Catalysis of the reaction: digallate + H(2)O = 2 gallate + H(+). CHEBI:86044 18-hydroxyoleoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86044 CL:0000019 sperm biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000019 spermatozoon|spermatozoid|sperm cell A mature male germ cell that develops from a spermatid. GO:0050319 tartrate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050319 MetaCyc:TARTRATE-DECARBOXYLASE-RXN|RHEA:13317|EC:4.1.1.73|KEGG_REACTION:R01751 (R,R)-tartrate carboxy-lyase (D-glycerate-forming)|(R,R)-tartrate carboxy-lyase activity Catalysis of the reaction: L-tartrate + H(+) = D-glycerate + CO(2). CHEBI:86045 O-acetyl-D-carnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86045 CHEBI:86046 18-hydroxyoctadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86046 CHEBI:86048 1-acyl-2-[(R)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86048 CL:0000011 migratory trunk neural crest cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000011 Cell that is part of the migratory trunk neural crest population. Migratory trunk neural crest cells develop from premigratory trunk neural crest cells and have undergone epithelial to mesenchymal transition and delamination. CL:0000014 germ line stem cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000014 germline stem cell CL:0000015 male germ cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000015 Male germ cell is a germ cell that supports male gamete production. CL:0000016 male germ line stem cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000016 GO:0050323 taurine dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050323 KEGG_REACTION:R07167|MetaCyc:TAURINE-DEHYDROGENASE-RXN|EC:1.4.99.2|RHEA:18709 taurine:(acceptor) oxidoreductase (deaminating)|taurine:acceptor oxidoreductase (deaminating) Catalysis of the reaction: A + H(2)O + taurine = AH(2) + NH(4)(+) + sulfoacetaldehyde. GO:0050324 taurocyamine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050324 MetaCyc:TAUROCYAMINE-KINASE-RXN|RHEA:22516|KEGG_REACTION:R03785|EC:2.7.3.4 taurocyamine phosphotransferase activity|ATP:taurocyamine N-phosphotransferase activity|ATP:taurocyamine phosphotransferase activity Catalysis of the reaction: ATP + taurocyamine = N-phosphotaurocyamine + ADP + 2 H(+). GO:0050321 tau-protein kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050321 EC:2.7.11.26|MetaCyc:TAU-PROTEIN-KINASE-RXN TPK I|tau protein kinase activity|protein tau kinase activity|tau kinase activity|TPK II|TPK|[Tau protein] kinase activity|tau-tubulin kinase activity|glycogen synthase kinase-3beta activity|CDK5/p23|TTK|tau-protein kinase I activity|cdk5/p20|brain protein kinase PK40erk activity|STK31|GSK|ATP:tau-protein O-phosphotransferase activity|tau-protein kinase II activity Catalysis of the reaction: ATP + tau-protein = ADP + O-phospho-tau-protein. GO:0050322 taurine-2-oxoglutarate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050322 RHEA:16353|MetaCyc:RXN-2301|EC:2.6.1.55 taurine--glutamate transaminase activity|taurine aminotransferase activity|taurine:2-oxoglutarate aminotransferase activity|taurine transaminase activity|taurine--alpha-ketoglutarate aminotransferase activity Catalysis of the reaction: taurine + 2-oxoglutarate = sulfoacetaldehyde + L-glutamate. CHEBI:86071 caffeyl alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86071 GO:0050327 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050327 GO:0050328 tetrahydroberberine oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050328 EC:1.3.3.8|MetaCyc:TETRAHYDROBERBERINE-OXIDASE-RXN|RHEA:13489 (S)-tetrahydroberberine:oxygen oxidoreductase activity|(S)-THB oxidase activity|THB oxidase activity Catalysis of the reaction: (S)-tetrahydroberberine + 2 O2 = berberine + 2 H2O2. GO:0050325 tauropine dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050325 RHEA:12580|MetaCyc:TAUROPINE-DEHYDROGENASE-RXN|EC:1.5.1.23|KEGG_REACTION:R01683 N2-(D-1-carboxyethyl)taurine:NAD+ oxidoreductase (taurine-forming)|2-N-(D-1-carboxyethyl)taurine:NAD+ oxidoreductase (taurine-forming) Catalysis of the reaction: H(2)O + NAD(+) + tauropine = H(+) + NADH + pyruvate + taurine. GO:0050326 taxifolin 8-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050326 EC:1.14.13.19|MetaCyc:TAXIFOLIN-8-MONOOXYGENASE-RXN taxifolin hydroxylase activity|taxifolin,NAD(P)H:oxygen oxidoreductase (8-hydroxylating) Catalysis of the reaction: taxifolin + NAD(P)H + H+ + O2 = 2,3-dihydrogossypetin + NAD(P)+ + H2O. CHEBI:86074 (24S,25)-dihydroxycholesterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86074 GO:0050329 tetrahydroxypteridine cycloisomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050329 EC:5.5.1.3|KEGG_REACTION:R04154|RHEA:18097|MetaCyc:TETRAHYDROXYPTERIDINE-CYCLOISOMERASE-RXN tetrahydroxypteridine lyase (isomerizing) Catalysis of the reaction: tetrahydroxypteridine = H(+) + xanthine-8-carboxylate. CHEBI:86077 O-butenoylcarnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86077 GO:0015997 obsolete ubiquinone biosynthetic process monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015997 ubiquinone biosynthetic process monooxygenase activity|coenzyme Q biosynthetic process monooxygenase activity|coenzyme Q biosynthesis monooxygenase activity|ubiquinone formation monooxygenase activity|ubiquinone synthesis monooxygenase activity|ubiquinone anabolism monooxygenase activity OBSOLETE. (Was not defined before being made obsolete). GO:0015998 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015998 GO:0015999 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015999 PR:000000033 tumor necrosis factor, TNF-like biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000000033 A protein with a core domain composition consisting of an N-terminal cytosolic domain, a type II transmembrane domain and a C-terminal TNF domain (Pfam:PF00229). GO:0015993 obsolete molecular hydrogen transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015993 OBSOLETE. The directed movement of molecular hydrogen (H2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. PR:000000034 BMP biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000000034 A TGF-beta-like cystine-knot cytokine that is related to the transforming growth factor-beta, anti-Muellerian hormone, and activin/inhibin protein families, which are all involved in the regulation of cell growth and differentiation. These are produced as dimeric precursors and undergo post-translational processing for activation, requiring cleavage to release bioactive the C-terminal peptide. BMP is involved in body patterning and morphogenesis. BMP signals are transmitted through specific type 2 and type 1 receptors. GO:0015994 chlorophyll metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015994 chlorophyll metabolism The chemical reactions and pathways involving chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment. GO:0015995 chlorophyll biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015995 MetaCyc:CHLOROPHYLL-SYN chlorophyll anabolism|chlorophyll synthesis|chlorophyll biosynthesis|chlorophyll formation The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors. GO:0015996 chlorophyll catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015996 chlorophyll degradation|chlorophyll breakdown|chlorophyll catabolism The chemical reactions and pathways resulting in the breakdown of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, into less complex products. CHEBI:37097 adenosine 3'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37097 CHEBI:37098 3-hydroxyoctanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37098 GO:0015990 electron transport coupled proton transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015990 The transport of protons against an electrochemical gradient, using energy from electron transport. GO:0015991 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015991 GO:0015992 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015992 CHEBI:37096 adenosine 5'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37096 GO:0050320 tartrate epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050320 KEGG_REACTION:R02546|RHEA:22212|EC:5.1.2.5|MetaCyc:TARTRATE-EPIMERASE-RXN tartaric racemase activity Catalysis of the reaction: L-tartrate = (2R,3S)-tartrate. CHEBI:37099 (R)-3-hydroxyoctanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37099 GO:0050334 thiaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050334 EC:3.5.99.2|RHEA:17509|KEGG_REACTION:R02133|MetaCyc:THIAMINASE-RXN thiaminase II activity Catalysis of the reaction: H(2)O + thiamine = 4-amino-5-hydroxymethyl-2-methylpyrimidine + 5-(2-hydroxyethyl)-4-methylthiazole + H(+). GO:0050335 thiocyanate isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050335 MetaCyc:THIOCYANATE-ISOMERASE-RXN|RHEA:10004|KEGG_REACTION:R04010|EC:5.99.1.1 isothiocyanate isomerase activity|benzyl-thiocyanate isomerase activity Catalysis of the reaction: benzyl isothiocyanate = benzyl thiocyanate. GO:0050332 thiamine pyridinylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050332 KEGG_REACTION:R02863|MetaCyc:THIAMIN-PYRIDINYLASE-RXN|RHEA:17697|EC:2.5.1.2 thiamin pyridinolase activity|thiaminase I activity|thiamine pyridinolase activity|thiamine hydrolase activity|thiamine:base 2-methyl-4-aminopyrimidine-5-methenyltransferase activity|thiamin pyridinylase activity|thiamin hydrolase activity|pyrimidine transferase activity|thiamin:base 2-methyl-4-aminopyrimidine-5-methenyltransferase activity Catalysis of the reaction: pyridine + thiamine = 5-(2-hydroxyethyl)-4-methylthiazole + heteropyrithiamine. GO:0050333 thiamin-triphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050333 EC:3.6.1.28|RHEA:11744|Reactome:R-HSA-965067|KEGG_REACTION:R00618|MetaCyc:THIAMIN-TRIPHOSPHATASE-RXN thiamine-triphosphate phosphohydrolase activity|ThTPase activity|thiamine-triphosphatase activity Catalysis of the reaction: H(2)O + thiamine triphosphate = H(+) + phosphate + thiamine diphosphate. GO:0050338 thiosulfate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050338 RHEA:20549|MetaCyc:THIOSULFATE-DEHYDROGENASE-RXN|EC:1.8.2.2 thiosulphate dehydrogenase activity|thiosulfate:ferricytochrome-c oxidoreductase activity|tetrathionate synthase activity|thiosulfate oxidase activity|thiosulfate-oxidizing enzyme|thiosulfate-acceptor oxidoreductase activity Catalysis of the reaction: 2 thiosulfate + 2 ferricytochrome c = tetrathionate + 2 ferrocytochrome c. GO:0050339 thymidine-triphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050339 EC:3.6.1.39|RHEA:19013|MetaCyc:THYMIDINE-TRIPHOSPHATASE-RXN thymidine triphosphate nucleotidohydrolase activity|deoxythymidine-5'-triphosphatase activity|dTTPase activity|dTTP nucleotidohydrolase activity Catalysis of the reaction: dTTP + H2O = dTDP + phosphate. GO:0050336 thioethanolamine S-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050336 MetaCyc:THIOETHANOLAMINE-S-ACETYLTRANSFERASE-RXN|EC:2.3.1.11|KEGG_REACTION:R03668|RHEA:23280 thioltransacetylase B activity|acetyl-CoA:thioethanolamine S-acetyltransferase activity|acetyl-CoA:2-aminoethanethiol S-acetyltransferase activity|thioethanolamine acetyltransferase activity Catalysis of the reaction: acetyl-CoA + cysteamine = S-acetylcysteamine + CoA. CHEBI:86062 abietatriene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86062 GO:0050337 thiosulfate-thiol sulfurtransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050337 Reactome:R-HSA-1655879|RHEA:14505|EC:2.8.1.3|MetaCyc:THIOSULFATE--THIOL-SULFURTRANSFERASE-RXN thiosulphate-thiol sulphurtransferase activity|thiosulfate:thiol sulfurtransferase activity|sulfane sulfurtransferase activity|sulfane reductase activity|glutathione-dependent thiosulfate reductase activity Catalysis of the reaction: thiosulfate + 2 glutathione = sulfite + glutathione disulfide + sulfide. CHEBI:86066 O-tetradecenoylcarnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86066 PR:000000046 TGF-beta biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000000046 transforming growth factor beta A TGF-beta-like cystine-knot cytokine whose propeptide region is a latent associated peptide (LAP) that remains associated to the mature TGF-beta after cleavage and secretion, keeping TGF-beta inactive. TGF-beta is the founding member of the cystine-knot cytokine family, and is related to the activin/inhibin, anti-Muellerian hormone, and bone morphogenic protein families, which are all involved in the regulation of cell growth and differentiation. GO:0050330 theanine hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050330 KEGG_REACTION:R02930|EC:3.5.1.65|RHEA:18013|MetaCyc:THEANINE-HYDROLASE-RXN N5-ethyl-L-glutamine amidohydrolase activity|L-theanine amidohydrolase activity|5-N-ethyl-L-glutamine amidohydrolase activity Catalysis of the reaction: N(5)-ethyl-L-glutamine + H(2)O = L-glutamate + ethylamine. GO:0050331 thiamine-diphosphate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050331 Reactome:R-HSA-997381|EC:2.7.4.15|MetaCyc:THIAMIN-DIPHOSPHATE-KINASE-RXN|RHEA:11240 protein bound thiamin diphosphate:ATP phosphoryltransferase activity|TDP kinase activity|thiamin diphosphate kinase activity|ATP:thiamine-diphosphate phosphotransferase activity|thiamin pyrophosphate kinase activity|thiamine diphosphate kinase activity|thiamin diphosphate phosphotransferase activity|thiamin-diphosphate kinase activity|ATP:thiamin-diphosphate phosphotransferase activity Catalysis of the reaction: ATP + thiamin diphosphate = ADP + thiamin triphosphate. GO:0050345 trans-epoxysuccinate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050345 MetaCyc:TRANS-EPOXYSUCCINATE-HYDROLASE-RXN|KEGG_REACTION:R02547|RHEA:20740|EC:3.3.2.4 trans-2,3-epoxysuccinate hydrolase activity|tartrate epoxydase activity|trans-epoxysuccinate hydratase activity Catalysis of the reaction: trans-2,3-epoxysuccinate + H(2)O = (2R,3S)-tartrate. GO:0050346 trans-L-3-hydroxyproline dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050346 MetaCyc:TRANS-L-3-HYDROXYPROLINE-DEHYDRATASE-RXN|EC:4.2.1.77|RHEA:10320|KEGG_REACTION:R04374 trans-L-3-hydroxyproline hydro-lyase (Delta1-pyrroline 2-carboxylate-forming)|trans-L-3-hydroxyproline hydro-lyase activity Catalysis of the reaction: trans-L-3-hydroxyproline = 1-pyrroline-2-carboxylate + H(2)O + H(+). GO:0050343 trans-2-enoyl-CoA reductase (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050343 MetaCyc:TRANS-2-ENOYL-COA-REDUCTASE-NAD+-RXN|RHEA:18177|EC:1.3.1.44 acyl-CoA:NAD+ trans-2-oxidoreductase activity Catalysis of the reaction: acyl-CoA + NAD+ = trans-didehydroacyl-CoA + NADH. GO:0050344 trans-cinnamate 2-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050344 EC:1.14.13.14|RHEA:10956|MetaCyc:TRANS-CINNAMATE-2-MONOOXYGENASE-RXN|KEGG_REACTION:R02254 cinnamate 2-hydroxylase activity|trans-cinnamate,NADPH:oxygen oxidoreductase (2-hydroxylating)|cinnamic 2-hydroxylase activity|cinnamic acid 2-hydroxylase activity|cinnamate 2-monooxygenase activity|trans-cinnamic acid 2-hydroxylase activity Catalysis of the reaction: trans-cinnamate + H(+) + NADPH + O(2) = 2-coumarate + H(2)O + NADP(+). GO:0050349 triacetate-lactonase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050349 MetaCyc:TRIACETATE-LACTONASE-RXN|RHEA:22260|EC:3.1.1.38|KEGG_REACTION:R03702 triacetolactone lactonohydrolase activity|triacetate lactone hydrolase activity|triacetic lactone hydrolase activity|TAL hydrolase activity|triacetic acid lactone hydrolase activity Catalysis of the reaction: H(2)O + triacetate lactone = triacetate. CHEBI:86094 1-tetradecanoyl-2-[(9Z,12Z)-octadecadienoyl]-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86094 GO:0050347 trans-octaprenyltranstransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050347 RHEA:11324|KEGG_REACTION:R07267 SPP synthase activity|(E)-octaprenyl-diphosphate:isopentenyl-diphosphate octaprenyltranstransferase activity|terpenyl pyrophosphate synthetase activity|trans-prenyltransferase activity|terpenoidallyltransferase activity|all-trans-nonaprenyl-diphosphate synthase activity|solanesyl-diphosphate synthase activity|solanesyl pyrophosphate synthetase activity|polyprenylpyrophosphate synthetase activity|nonaprenyl pyrophosphate synthetase activity Catalysis of the reaction: all-trans-octaprenyl diphosphate + isopentenyl diphosphate = all-trans-nonaprenyl diphosphate + diphosphate. CHEBI:37080 acrylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37080 GO:0050348 trehalose O-mycolyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050348 EC:2.3.1.122|MetaCyc:RXN1G-874|KEGG_REACTION:R07248|RHEA:23472 alpha,alpha'-trehalose 6-monomycolate:alpha,alpha'-trehalose mycolyltransferase activity|alpha,alpha'-trehalose-6-mycolate:alpha,alpha'-trehalose-6-mycolate 6'-mycolyltransferase activity Catalysis of the reaction: 2 alpha,alpha'-trehalose 6-mycolate = alpha,alpha'-trehalose 6,6'-bismycolate + alpha,alpha-trehalose. CHEBI:86096 (25R)-3beta-hydroxycholest-5-en-26-al biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86096 CHEBI:37081 3-aminobutanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37081 CHEBI:86098 (25R)-3beta-hydroxycholest-5-en-26-oate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86098 GO:0015979 photosynthesis biolink:BiologicalProcess go-plus goslim_plant|goslim_pir|goslim_metagenomics|goslim_generic|goslim_chembl http://purl.obolibrary.org/obo/GO_0015979 Wikipedia:Photosynthesis The synthesis by organisms of organic chemical compounds, especially carbohydrates, from carbon dioxide (CO2) using energy obtained from light rather than from the oxidation of chemical compounds. PR:000024067 homoserine kinase biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000024067 thrB|HK|HSK A protein that is a translation product of the Escherichia coli K-12 thrB gene or a 1:1 ortholog thereof. GO:0015975 energy derivation by oxidation of reduced inorganic compounds biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015975 Wikipedia:Lithotrophy lithotrophy|chemolithotrophy|chemolithotrophie The chemical reactions and pathways by which a cell derives energy from inorganic compounds; results in the oxidation of the compounds from which energy is released. GO:0015976 carbon utilization biolink:BiologicalProcess go-plus goslim_pir|goslim_chembl http://purl.obolibrary.org/obo/GO_0015976 Wikipedia:Heterotroph carbon utilization by utilization of organic compounds|heterotrophy A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary carbon sources and then activates genes to scavenge the last traces of the primary carbon source and to transport and metabolize alternative carbon sources such as carbon dioxide or carbonic acid. The utilization process begins when the cell or organism detects carbon levels, includes the activation of genes whose products detect, transport or metabolize carbon-containing substances, and ends when carbon is incorporated into the cell or organism's metabolism. GO:0015977 carbon fixation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015977 Wikipedia:Carbon_fixation autotrophic CO2 fixation|autotrophy|carbon dioxide fixation|autotrophic CO2 fixation pathway A metabolic process in which carbon (usually derived from carbon dioxide) is incorporated into organic compounds (usually carbohydrates). GO:0015978 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015978 GO:0015971 guanosine tetraphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015971 guanosine tetraphosphate (5'-ppGpp-3') catabolic process|guanosine tetraphosphate catabolism|guanosine tetraphosphate degradation|guanosine tetraphosphate breakdown|guanosine tetraphosphate (5'-ppGpp-3') catabolism The chemical reactions and pathways resulting in the breakdown of guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates. GO:0015972 guanosine pentaphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015972 guanosine pentaphosphate (5'-pppGpp-3') metabolic process|guanosine pentaphosphate metabolism|guanosine pentaphosphate (5'-pppGpp-3') metabolism The chemical reactions and pathways involving guanine pentaphosphate (5'-pppGpp-3'), a derivative of guanine riboside with five phosphates. GO:0015973 guanosine pentaphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015973 guanosine pentaphosphate biosynthesis|guanosine pentaphosphate (5'-pppGpp-3') biosynthesis|guanosine pentaphosphate (5'-pppGpp-3') biosynthetic process|guanosine pentaphosphate anabolism|guanosine pentaphosphate synthesis|guanosine pentaphosphate formation The chemical reactions and pathways resulting in the formation of guanine pentaphosphate (5'-pppGpp-3'), a derivative of guanine riboside with five phosphates. GO:0015974 guanosine pentaphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015974 guanosine pentaphosphate degradation|guanosine pentaphosphate (5'-pppGpp-3') catabolic process|guanosine pentaphosphate breakdown|guanosine pentaphosphate catabolism|guanosine pentaphosphate (5'-pppGpp-3') catabolism The chemical reactions and pathways resulting in the breakdown of guanine pentaphosphate (5'-pppGpp-3'), a derivative of guanine riboside with five phosphates. CHEBI:37075 ribonucleoside 5'-diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37075 CHEBI:37076 ribonucleoside 5'-triphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37076 GO:0015970 guanosine tetraphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015970 guanosine tetraphosphate anabolism|guanosine tetraphosphate biosynthesis|guanosine tetraphosphate synthesis|guanosine tetraphosphate formation|guanosine tetraphosphate (5'-ppGpp-3') biosynthetic process|guanosine tetraphosphate (5'-ppGpp-3') biosynthesis The chemical reactions and pathways resulting in the formation of guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates. GO:0050341 thymine dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050341 MetaCyc:THYMINE-DIOXYGENASE-RXN|EC:1.14.11.6|RHEA:10316 5-hydroxy-methyluracil dioxygenase activity|5-hydroxymethyluracil oxygenase activity|thymine,2-oxoglutarate dioxygenase activity|thymine 7-hydroxylase activity|thymine,2-oxoglutarate:oxygen oxidoreductase (7-hydroxylating) Catalysis of the reaction: thymine + 2-oxoglutarate + O2 = 5-hydroxymethyluracil + succinate + CO2. CHEBI:37079 2-methylacetoacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37079 GO:0050342 tocopherol O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050342 MetaCyc:TOCOPHEROL-O-METHYLTRANSFERASE-RXN|EC:2.1.1.95|RHEA:24012 gamma-tocopherol methyltransferase activity|S-adenosyl-L-methionine:gamma-tocopherol 5-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + gamma-tocopherol = S-adenosyl-L-homocysteine + alpha-tocopherol. CHEBI:37077 ribonucleoside 5'-tetraphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37077 GO:0050340 thymidylate 5'-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050340 RHEA:11080|EC:3.1.3.35|MetaCyc:THYMIDYLATE-5-PHOSPHATASE-RXN deoxythymidylate phosphohydrolase activity|thymidylate 5'-phosphohydrolase activity|thymidylate 5'-nucleotidase activity|deoxythymidylic 5'-nucleotidase activity|thymidylate 5' phosphatase activity|dTMPase activity|thymidylate nucleotidase activity|deoxythymidylate 5'-nucleotidase activity Catalysis of the reaction: thymidylate + H2O = thymidine + phosphate. GO:0050356 tropine dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050356 MetaCyc:TROPINE-DEHYDROGENASE-RXN|KEGG_REACTION:R02832|RHEA:18357|EC:1.1.1.206 tropine:NADP+ 3alpha-oxidoreductase activity Catalysis of the reaction: NADP(+) + tropine = H(+) + NADPH + tropinone. GO:0050357 tropinesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050357 MetaCyc:TROPINESTERASE-RXN|EC:3.1.1.10|RHEA:23304|KEGG_REACTION:R03563 tropine esterase activity|atropine esterase activity|atropine acylhydrolase activity|atropinesterase activity|atropinase activity Catalysis of the reaction: atropine + H(2)O = H(+) + tropate + tropine. GO:0050354 triokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050354 KEGG_REACTION:R01059|RHEA:13941|Reactome:R-HSA-70349|MetaCyc:TRIOKINASE-RXN|EC:2.7.1.28 ATP:D-glyceraldehyde 3-phosphotransferase activity|triose kinase activity|D-triokinase activity|trio triose kinase (phosphorylating) Catalysis of the reaction: D-glyceraldehyde + ATP = D-glyceraldehyde 3-phosphate + ADP + 2 H(+). GO:0050355 triphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050355 KEGG_REACTION:R00138|EC:3.6.1.25|MetaCyc:TRIPHOSPHATASE-RXN|RHEA:14157 inorganic triphosphatase activity|tripolyphosphatase activity|triphosphate phosphohydrolase activity Catalysis of the reaction: H(2)O + triphosphate = diphosphate + phosphate. GO:0050358 tropinone reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050358 KEGG_REACTION:R06734|RHEA:24244|EC:1.1.1.236|MetaCyc:TROPINONE-REDUCTASE-RXN tropinone (psi-tropine-forming) reductase activity|pseudotropine:NADP+ 3-oxidoreductase activity|tropinone reductase II activity|pseudotropine forming tropinone reductase activity Catalysis of the reaction: NADP(+) + pseudotropine = H(+) + NADPH + tropinone. GO:0050359 tropomyosin kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050359 EC:2.7.11.28|MetaCyc:TROPOMYOSIN-KINASE-RXN ATP:tropomyosin O-phosphotransferase activity|STK|tropomyosin kinase (phosphorylating) activity Catalysis of the reaction: ATP + tropomyosin = ADP + O-phosphotropomyosin. CHEBI:37092 2'-deoxycytidine phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37092 CHEBI:86087 4beta,24S-dihydroxycholesterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86087 GO:0015986 ATP synthesis coupled proton transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015986 chemiosmosis The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis. GO:0015987 GTP synthesis coupled proton transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015987 The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that powers GTP synthesis. GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015988 The transport of protons across a membrane and against an electrochemical gradient, using energy from a source such as ATP hydrolysis, light, or electron transport. GO:0015989 light-driven proton transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015989 The transport of protons against an electrochemical gradient, using energy from light. GO:0015982 obsolete antiport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015982 antiport OBSOLETE. The process of coupled solute translocation in which two solutes equilibrate across an osmotic barrier, the translocation of solute being coupled to the translocation of the other in the opposite direction. GO:0015983 obsolete symport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015983 symport OBSOLETE. The process of solute translocation in which two solutes equilibrate across an osmotic barrier, and the translocation of one solute is coupled to the translocation of the other in the same direction. GO:0015984 obsolete uniport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015984 uniport OBSOLETE. The process of noncoupled solute translocation or facilitated diffusion. GO:0015985 energy coupled proton transport, down electrochemical gradient biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015985 The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that provides energy for the synthesis of ATP or GTP. CHEBI:37086 C-nucleoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37086 GO:0015980 energy derivation by oxidation of organic compounds biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015980 chemoorganotrophy The chemical reactions and pathways by which a cell derives energy from organic compounds; results in the oxidation of the compounds from which energy is released. CHEBI:37084 3-hydroxyisovaleric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37084 GO:0015981 obsolete passive proton transport, down the electrochemical gradient biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015981 passive proton transport, down the electrochemical gradient OBSOLETE. The passive movement of protons from areas of high proton concentration and electrical potential to areas where concentration and electrical potential are low. GO:0050352 trimethylamine-oxide aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050352 KEGG_REACTION:R02512|EC:4.1.2.32|UM-BBD_reactionID:r1409|MetaCyc:TRIMETHYLAMINE-OXIDE-ALDOLASE-RXN|RHEA:20217 trimethylamine-N-oxide formaldehyde-lyase activity|trimethylamine N-oxide demethylase activity|trimethylamine-N-oxide formaldehyde-lyase (dimethylamine-forming)|trimethylamine N-oxide formaldehyde-lyase activity|trimethylamine N-oxide aldolase activity Catalysis of the reaction: H(+) + trimethylamine N-oxide = dimethylamine + formaldehyde. GO:0050353 trimethyllysine dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050353 MetaCyc:TRIMETHYLLYSINE-DIOXYGENASE-RXN|KEGG_REACTION:R03451|RHEA:14181|EC:1.14.11.8|Reactome:R-HSA-71241 TMLD activity|epsilon-trimethyllysine 2-oxoglutarate dioxygenase activity|6-N,6-N,6-N-trimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)|TML dioxygenase activity|N6,N6,N6-trimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)|trimethyllysine,2-oxoglutarate dioxygenase activity|trimethyllysine alpha-ketoglutarate dioxygenase activity|TML hydroxylase activity|TML-alpha-ketoglutarate dioxygenase activity Catalysis of the reaction: 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysine + O(2) = 3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine + CO(2) + succinate. GO:0050350 trihydroxystilbene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050350 EC:2.3.1.95|MetaCyc:TRIHYDROXYSTILBENE-SYNTHASE-RXN|RHEA:11936 stilbene synthase activity|malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)|resveratrol synthase activity Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + 3,4',5-trihydroxy-stilbene + 4 CO2. CHEBI:37088 anthrol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37088 GO:0050351 trimetaphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050351 MetaCyc:TRIMETAPHOSPHATASE-RXN|RHEA:11088|EC:3.6.1.2|KEGG_REACTION:R02504 trimetaphosphate hydrolase activity|inorganic trimetaphosphatase activity Catalysis of the reaction: H(2)O + trimetaphosphate = 2 H(+) + triphosphate. CHEBI:37089 ortho-fused tricyclic hydrocarbon biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37089 GO:0050367 tyrosine-arginine ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050367 KEGG_REACTION:R00735|EC:6.3.2.24|MetaCyc:TYROSINE--ARGININE-LIGASE-RXN|RHEA:15345 kyotorphin synthetase activity|L-tyrosine:L-arginine ligase (AMP-forming)|kyotorphin-synthesizing enzyme activity|kyotorphin synthase activity|tyrosyl-arginine synthase activity Catalysis of the reaction: L-arginine + L-tyrosine + ATP = L-tyrosyl-L-arginine + AMP + diphosphate + 2 H(+). GO:0001312 obsolete replication of extrachromosomal rDNA circles involved in replicative cell aging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001312 replication of extrachromosomal rDNA circles during replicative cell aging|replication of extrachromosomal rDNA circles during replicative cell ageing|replication of extrachromosomal ribosomal DNA circles during replicative cell aging OBSOLETE. Replication of rDNA following its excision from the chromosome of dividing cells as they age. Extrachromosomal rDNA forms a circle that contains at least one autonomously replicating sequence (ARS), which supports replication independent of chromosomal replication. GO:0050368 tyrosine 2,3-aminomutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050368 MetaCyc:TYROSINE-23-AMINOMUTASE-RXN|KEGG_REACTION:R00739|EC:5.4.3.6|RHEA:15781 L-tyrosine 2,3-aminomutase activity|tyrosine alpha,beta-mutase activity Catalysis of the reaction: L-tyrosine = 3-amino-3-(4-hydroxyphenyl)propanoate. GO:0001313 obsolete formation of extrachromosomal circular DNA involved in replicative cell aging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001313 assembly of extrachromosomal circular DNA involved in replicative cell aging|formation of extrachromosomal circular DNA during replicative cell ageing|formation of extrachromosomal circular DNA during replicative cell aging OBSOLETE. Excision from the chromosome and circularization of a region of chromosomal DNA, generally, but not always, via homologous recombination between direct tandem repeats, in dividing cells as they age. GO:0050365 tryptophanamidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050365 MetaCyc:TRYPTOPHANAMIDASE-RXN|EC:3.5.1.57|KEGG_REACTION:R00682|RHEA:11012 L-tryptophanamide amidohydrolase activity|tryptophan aminopeptidase|L-tryptophan aminopeptidase Catalysis of the reaction: L-tryptophanamide + H(2)O = L-tryptophan + NH(4)(+). GO:0001314 obsolete replication of extrachromosomal circular DNA involved in replicative cell aging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001314 replication of extrachromosomal circular DNA during replicative cell ageing|replication of extrachromosomal circular DNA during replicative cell aging OBSOLETE. Replication of circular DNA following excision from the chromosome of dividing cells as they age; replication of extrachromosomal circular DNA generally occurs independently of chromosomal replication. GO:0050366 tyramine N-feruloyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050366 EC:2.3.1.110|MetaCyc:TYRAMINE-N-FERULOYLTRANSFERASE-RXN|RHEA:19685 feruloyl-CoA tyramine N-feruloyl-CoA transferase activity|tyramine N-feruloyl-CoA transferase activity|feruloyl-CoA:tyramine N-(hydroxycinnamoyl)transferase activity|tyramine feruloyltransferase activity|feruloyltyramine synthase activity Catalysis of the reaction: feruloyl-CoA + tyramine = CoA + N-feruloyltyramine. GO:0001315 age-dependent response to reactive oxygen species biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001315 age-dependent response to ROI|age-dependent response to AOS|age-dependent response to reactive oxidative species|age-dependent response to reactive oxygen intermediate|age-dependent response to ROS|age-dependent response to active oxygen species Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of reactive oxygen species, where the change varies according to the age of the cell or organism. CHEBI:144413 Phospho-anandamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_144413 GO:0001310 obsolete extrachromosomal rDNA circle accumulation involved in replicative cell aging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001310 extrachromosomal ribosomal DNA circle accumulation during replicative cell aging|extrachromosomal rDNA circle accumulation during replicative cell ageing|extrachromosomal rDNA circle accumulation during replicative cell aging OBSOLETE. Increase in abundance of circular DNA molecules containing ribosomal DNA repeats in dividing cells as they age. These molecules originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats, and then replicated independently of chromosomal replication. GO:0050369 [tyrosine 3-monooxygenase] kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050369 EC:2.7.11.6|MetaCyc:2.7.11.6-RXN|RHEA:17133 STK4|tyrosine 3-monooxygenase kinase (phosphorylating) activity|ATP:tyrosine-3-monoxygenase phosphotransferase activity|pheochromocytoma tyrosine hydroxylase-associated kinase activity|tyrosine 3-monooxygenase kinase activity Catalysis of the reaction: ATP + [tyrosine-3-monooxygenase] = ADP + phospho-[tyrosine-3-monooxygenase]. GO:0001311 obsolete formation of extrachromosomal circular rDNA by homologous recombination involved in replicative cell aging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001311 assembly of extrachromosomal circular rDNA by homologous recombination involved in replicative cell aging|formation of extrachromosomal circular rDNA by homologous recombination during replicative cell aging|formation of extrachromosomal circular ribosomal DNA by homologous recombination during replicative cell aging|formation of extrachromosomal circular rDNA by homologous recombination during replicative cell ageing OBSOLETE. Excision from the chromosome and circularization of DNA molecules encoding ribosomal RNA in dividing cells as they age. GO:0015957 bis(5'-nucleosidyl) oligophosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015957 bis(5'-nucleosidyl) oligophosphate biosynthesis|bis(5'-nucleosidyl) oligophosphate anabolism|bis(5'-nucleosidyl) oligophosphate synthesis|bis(5'-nucleosidyl) oligophosphate formation The chemical reactions and pathways resulting in the formation of a bis(5'-nucleosidyl) oligophosphate, a compound formed of two nucleosides joined together through their 5' carbons by a chain of phosphate molecules. GO:0015958 bis(5'-nucleosidyl) oligophosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015958 bis(5'-nucleosidyl) oligophosphate breakdown|bis(5'-nucleosidyl) oligophosphate catabolism|bis(5'-nucleosidyl) oligophosphate degradation The chemical reactions and pathways resulting in the breakdown of a bis(5'-nucleosidyl) oligophosphate, a compound formed of two nucleosides joined together through their 5' carbons by a chain of phosphate molecules. GO:0015959 diadenosine polyphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015959 diadenosine polyphosphate metabolism The chemical reactions and pathways involving diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached. GO:0015953 pyrimidine nucleotide interconversion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015953 The chemical reactions and pathways by which a pyrimidine nucleotide is synthesized from another pyrimidine nucleotide. GO:0015954 pyrimidine ribonucleotide interconversion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015954 The chemical reactions and pathways by which a pyrimidine ribonucleotide is synthesized from another pyrimidine ribonucleotide. GO:0015955 pyrimidine deoxyribonucleotide interconversion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015955 The chemical reactions and pathways by which a pyrimidine deoxyribonucleotide is synthesized from another pyrimidine deoxyribonucleotide. CHEBI:37059 purine nucleoside tetraphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37059 GO:0015956 bis(5'-nucleosidyl) oligophosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015956 bis(5'-nucleosidyl) oligophosphate metabolism The chemical reactions and pathways involving a bis(5'-nucleosidyl) oligophosphate, a compound formed of two nucleosides joined together through their 5' carbons by a chain of phosphate molecules. GO:0015950 purine nucleotide interconversion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015950 The chemical reactions and pathways by which a purine nucleotide is synthesized from another purine nucleotide. GO:0015951 purine ribonucleotide interconversion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015951 The chemical reactions and pathways by which a purine ribonucleotide is synthesized from another purine ribonucleotide. GO:0015952 purine deoxyribonucleotide interconversion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015952 The chemical reactions and pathways by which a purine deoxyribonucleotide is synthesized from another purine deoxyribonucleotide. GO:0050360 tryptophan 2'-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050360 EC:1.13.99.3|RHEA:22620|MetaCyc:TRYPTOPHAN-2-DIOXYGENASE-RXN tryptophan side-chain oxidase activity|tryptophan side-chain alpha,beta-oxidase activity|TSO activity|tryptophan side chain oxidase activity|TSO I|tryptophan side chain oxidase type I|indolyl-3-alkan alpha-hydroxylase activity|TSO II|indole-3-alkane alpha-hydroxylase activity|tryptophan side chain oxidase II|L-tryptophan:oxygen 2'-oxidoreductase (side-chain-cleaving) Catalysis of the reaction: L-tryptophan + O2 = 3-indoleglycolaldehyde + CO2 + NH3. CHEBI:37054 3-hydroxybutyrate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37054 CHEBI:37051 3-hydroxy-2-methylbutanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37051 CHEBI:37052 (2S,3S)-3-hydroxy-2-methylbutanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37052 GO:0001316 obsolete age-dependent response to reactive oxygen species involved in replicative cell aging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001316 age-dependent response to reactive oxygen species during replicative cell aging|age-dependent response to ROI during replicative cell aging|age-dependent response to AOS during replicative cell aging|age-dependent response to reactive oxygen species during replicative cell ageing|age-dependent response to reactive oxidative species during replicative cell aging|age-dependent response to reactive oxygen intermediate during replicative cell aging|age-dependent response to active oxygen species during replicative cell aging|age-dependent response to ROS during replicative cell aging OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) occurring during the process of replicative cell aging as a result of reactive oxygen species, where the change varies according to the age of the cell or organism. GO:0050363 tryptophan dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050363 EC:1.4.1.19|MetaCyc:TRYPTOPHAN-DEHYDROGENASE-RXN L-tryptophan dehydrogenase activity|TrpDH activity|L-Trp-dehydrogenase activity|TDH|NAD(P)+-L-tryptophan dehydrogenase activity|L-tryptophan:NAD(P)+ oxidoreductase (deaminating) Catalysis of the reaction: L-tryptophan + NAD(P)+ = (indol-3-yl)pyruvate + NH3 + NAD(P)H + H+. GO:0050364 tryptophan dimethylallyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050364 MetaCyc:TRYPTOPHAN-DIMETHYLALLYLTRANSFERASE-RXN|EC:2.5.1.34|RHEA:14173 DMAT synthetase activity|4-(gamma,gamma-dimethylallyl)tryptophan synthase activity|dimethylallylpyrophosphate:L-tryptophan dimethylallyltransferase activity|dimethylallylpyrophosphate:tryptophan dimethylallyl transferase activity|dimethylallyltryptophan synthetase activity|dimethylallyl-diphosphate:L-tryptophan dimethylallyltransferase activity Catalysis of the reaction: dimethylallyl diphosphate + L-tryptophan = diphosphate + 4-(3-methylbut-2-enyl)-L-tryptophan. GO:0001317 obsolete accumulation of oxidatively modified proteins involved in replicative cell aging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001317 accumulation of oxidatively modified proteins during replicative cell ageing|accumulation of oxidatively modified proteins during replicative cell aging OBSOLETE. Accumulation of proteins that have undergone reactions with reactive oxygen species in aging dividing cells and exhibit modifications such as increased protein carbonyl content, oxidized methionine, protein hydrophobicity, and cross-linking. CHEBI:37058 ribonucleoside tetraphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37058 GO:0050361 tryptophan 2-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050361 EC:1.13.12.3|KEGG_REACTION:R00679|MetaCyc:TRYPTOPHAN-2-MONOOXYGENASE-RXN|RHEA:16165 L-tryptophan:oxygen 2-oxidoreductase (decarboxylating) Catalysis of the reaction: L-tryptophan + O(2) = CO(2) + H(2)O + indole-3-acetamide. GO:0001318 obsolete formation of oxidatively modified proteins involved in replicative cell aging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001318 formation of oxidatively modified proteins during replicative cell aging|formation of oxidatively modified proteins during replicative cell ageing OBSOLETE. Chemical reaction, between proteins and reactive oxygen species, that occurs in dividing cells as they age and leads to a variety of changes in the affected proteins, including increases in protein carbonyl content, oxidized methionine, protein hydrophobicity, and cross-linking. GO:0050362 L-tryptophan:2-oxoglutarate aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050362 EC:2.6.1.27|MetaCyc:TRYPTOPHAN-AMINOTRANSFERASE-RXN|RHEA:14093 L-tryptophan transaminase activity|tryptophan transaminase activity|tryptophan aminotransferase activity|5-hydroxytryptophan-ketoglutaric transaminase activity|L-tryptophan aminotransferase activity|L-phenylalanine-2-oxoglutarate aminotransferase activity|hydroxytryptophan aminotransferase activity Catalysis of the reaction: L-tryptophan + 2-oxoglutarate = indolepyruvate + L-glutamate. GO:0001319 obsolete inheritance of oxidatively modified proteins involved in replicative cell aging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001319 inheritance of oxidatively modified proteins during replicative cell ageing|inheritance of oxidatively modified proteins during replicative cell aging OBSOLETE. A protein localization process in which progeny cells acquire, or are barred from acquiring, proteins that have been altered by reaction with reactive oxygen species in dividing aging cells. CHEBI:37056 nucleoside tetraphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37056 GO:0050378 UDP-glucuronate 4-epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050378 MetaCyc:PWY-4861|EC:5.1.3.6|KEGG_REACTION:R01385|MetaCyc:UDP-GLUCURONATE-4-EPIMERASE-RXN|RHEA:11404 UDP-galacturonate 4-epimerase activity|UDP-D-galacturonic acid 4-epimerase activity|uridine diphosphoglucuronate epimerase activity|uridine diphosphoglucuronic epimerase activity|UDP glucuronic epimerase activity|uridine diphospho-D-galacturonic acid|UDPglucuronate 4-epimerase activity Catalysis of the reaction: UDP-alpha-D-glucuronate = UDP-alpha-D-galacturonate. GO:0001323 obsolete age-dependent general metabolic decline involved in chronological cell aging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001323 age-dependent general metabolic decline during chronological cell ageing|age-dependent general metabolic decline during chronological cell aging OBSOLETE. A process of general metabolic decline that arises in non-dividing cells as they age, and alters cellular metabolism to cause a decline in cell function. GO:0001324 obsolete age-dependent response to oxidative stress involved in chronological cell aging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001324 age-dependent response to oxidative stress during chronological cell aging|age-dependent response to oxidative stress during chronological cell ageing OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) occurring in non-dividing cells as they age as a result of oxidative stress, where the change varies according to the age of the cell or organism. GO:0050379 UDP-glucuronate 5'-epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050379 EC:5.1.3.12|KEGG_REACTION:R01387|RHEA:14677|Reactome:R-HSA-2076371|MetaCyc:UDP-GLUCURONATE-5-EPIMERASE-RXN|Reactome:R-HSA-2024100 UDP-glucuronic acid epimerase activity|C-5-uronosyl epimerase activity|UDP-glucuronate 5' epimerase activity|UDP-glucuronic acid 5'-epimerase activity|uridine diphosphoglucuronate 5'-epimerase activity|UDPglucuronate 5'-epimerase activity Catalysis of the reaction: UDP-alpha-D-glucuronate = UDP-L-iduronate. GO:0050376 UDP-glucosamine 4-epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050376 MetaCyc:UDP-GLUCOSAMINE-EPIMERASE-RXN|RHEA:23492|EC:5.1.3.16 UDPglucosamine 4-epimerase activity|UDP-glucosamine epimerase activity Catalysis of the reaction: UDP-glucosamine = UDP-galactosamine. GO:0001325 formation of extrachromosomal circular DNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001325 assembly of extrachromosomal circular DNA Excision from the chromosome and circularization of a region of chromosomal DNA, generally, but not always, via homologous recombination between direct tandem repeats. GO:0050377 UDP-glucose 4,6-dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050377 EC:4.2.1.76|RHEA:21500|MetaCyc:UDP-GLUCOSE-46-DEHYDRATASE-RXN|KEGG_REACTION:R00293 UDPglucose 4,6-dehydratase activity|UDP-glucose 4,6-hydro-lyase (UDP-4-dehydro-6-deoxy-D-glucose-forming)|UDPglucose 4,6-hydro-lyase activity|UDP-D-glucose-4,6-hydrolyase activity|UDP-D-glucose oxidoreductase activity|UDP-glucose 4,6-hydro-lyase activity Catalysis of the reaction: UDP-D-glucose = H(2)O + UDP-4-dehydro-6-deoxy-D-glucose. GO:0001326 replication of extrachromosomal circular DNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001326 Replication of circular DNA following excision from the chromosome; replication of extrachromosomal circular DNA generally occurs independently of chromosomal replication. GO:0001320 obsolete age-dependent response to reactive oxygen species involved in chronological cell aging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001320 age-dependent response to AOS during chronological cell aging|age-dependent response to reactive oxidative species during chronological cell aging|age-dependent response to reactive oxygen intermediate during chronological cell aging|age-dependent response to reactive oxygen species during chronological cell ageing|age-dependent response to ROS during chronological cell aging|age-dependent response to active oxygen species during chronological cell aging|age-dependent response to reactive oxygen species during chronological cell aging|age-dependent response to ROI during chronological cell aging OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) occurring in non-dividing cells as they age as a result of reactive oxygen species, where the change varies according to the age of the cell or organism. GO:0001321 obsolete age-dependent general metabolic decline involved in replicative cell aging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001321 age-dependent general metabolic decline involved in replicative cell aging|age-dependent general metabolic decline during replicative cell ageing OBSOLETE. A process of general metabolic decline that arises in dividing cells as they age, and alters cellular metabolism to cause a decline in cell function. CHEBI:37070 2-methylbutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37070 GO:0001322 obsolete age-dependent response to oxidative stress involved in replicative cell aging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001322 age-dependent response to oxidative stress during replicative cell ageing|age-dependent response to oxidative stress during replicative cell aging OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) occurring in dividing cells as they age as a result of oxidative stress, where the change varies according to the age of the cell or organism. GO:0015968 stringent response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015968 Wikipedia:Stringent_response A specific global change in the metabolism of a bacterial cell (the downregulation of nucleic acid and protein synthesis, and the simultaneous upregulation of protein degradation and amino acid synthesis) as a result of starvation. GO:0015969 guanosine tetraphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015969 MetaCyc:PPGPPMET-PWY guanosine tetraphosphate (5'-ppGpp-3') metabolic process|guanosine tetraphosphate (5'-ppGpp-3') metabolism|guanosine tetraphosphate metabolism The chemical reactions and pathways involving guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates. GO:0015964 diadenosine triphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015964 diadenosine triphosphate degradation|diadenosine triphosphate breakdown|diadenosine triphosphate catabolism The chemical reactions and pathways resulting in the breakdown of diadenosine triphosphate, a derivative of the nucleoside adenosine with three phosphate groups attached. GO:0015965 diadenosine tetraphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015965 diadenosine tetraphosphate metabolism The chemical reactions and pathways involving diadenosine tetraphosphate, a derivative of the nucleoside adenosine with four phosphate groups attached. GO:0015966 diadenosine tetraphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015966 diadenosine tetraphosphate anabolism|diadenosine tetraphosphate synthesis|diadenosine tetraphosphate formation|diadenosine tetraphosphate biosynthesis The chemical reactions and pathways resulting in the formation of diadenosine tetraphosphate, a derivative of the nucleoside adenosine with four phosphate groups attached. GO:0015967 diadenosine tetraphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015967 diadenosine tetraphosphate catabolism|diadenosine tetraphosphate degradation|diadenosine tetraphosphate breakdown The chemical reactions and pathways resulting in the breakdown of diadenosine tetraphosphate, a derivative of the nucleoside adenosine with four phosphate groups attached. GO:0015960 diadenosine polyphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015960 diadenosine polyphosphate anabolism|diadenosine polyphosphate synthesis|diadenosine polyphosphate biosynthesis|diadenosine polyphosphate formation The chemical reactions and pathways resulting in the formation of diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached. GO:0015961 diadenosine polyphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015961 diadenosine polyphosphate catabolism|diadenosine polyphosphate degradation|diadenosine polyphosphate breakdown The chemical reactions and pathways resulting in the breakdown of diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached. GO:0015962 diadenosine triphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015962 diadenosine triphosphate metabolism The chemical reactions and pathways involving diadenosine triphosphate, a derivative of the nucleoside adenosine with three phosphate groups attached. GO:0015963 diadenosine triphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015963 diadenosine triphosphate biosynthesis|diadenosine triphosphate anabolism|diadenosine triphosphate synthesis|diadenosine triphosphate formation The chemical reactions and pathways resulting in the formation of diadenosine triphosphate, a derivative of the nucleoside adenosine with three phosphate groups attached. GO:0050370 tyrosine N-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050370 RHEA:22464|MetaCyc:TYROSINE-N-MONOOXYGENASE-RXN CYP79A1 activity|tyrosine N-hydroxylase activity|L-tyrosine,NADPH:oxygen oxidoreductase (N-hydroxylating) Catalysis of the reaction: tyrosine + O2 + NADPH + H+ = N-hydroxytyrosine + NADP+ + H2O. GO:0050371 tyrosine phenol-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050371 MetaCyc:TYROSINE-PHENOL-LYASE-RXN|KEGG_REACTION:R00728|EC:4.1.99.2|RHEA:21704 beta-tyrosinase activity|L-tyrosine phenol-lyase (deaminating; pyruvate-forming)|L-tyrosine phenol-lyase (deaminating) Catalysis of the reaction: L-tyrosine + H(2)O = NH(4)(+) + phenol + pyruvate. CHEBI:52684 butanediol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52684 CHEBI:37063 purine ribonucleoside tetraphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37063 GO:0050374 UDP-galacturonate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050374 RHEA:19725|EC:4.1.1.67|KEGG_REACTION:R02636|MetaCyc:UDP-GALACTURONATE-DECARBOXYLASE-RXN UDP-D-galacturonate carboxy-lyase activity|UDPgalacturonate decarboxylase activity|UDP-galacturonic acid decarboxylase activity|UDPGalUA carboxy lyase activity|UDP-D-galacturonate carboxy-lyase (UDP-L-arabinose-forming) Catalysis of the reaction: H(+) + UDP-alpha-D-galacturonate = CO(2) + UDP-L-arabinose. CHEBI:52680 5-(pentadeca-8,11,14-trien-1-yl)resorcinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52680 GO:0050375 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050375 CHEBI:52681 5-(pentadeca-8,11,14-trien-1-yl)resorcinol monomethyl ether biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52681 GO:0050372 ubiquitin-calmodulin ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050372 MetaCyc:UBIQUITIN--CALMODULIN-LIGASE-RXN ubiquityl-calmodulin synthetase activity|calmodulin:ubiquitin ligase (AMP-forming)|ubiquityl-calmodulin synthase activity|uCaM-synthetase activity|ubiquitin-calmodulin synthetase activity Catalysis of the reaction: n ATP + calmodulin + n ubiquitin = n AMP + n diphosphate + ubiquitin(n)-calmodulin. GO:0050373 UDP-arabinose 4-epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050373 KEGG_REACTION:R01473|RHEA:11320|EC:5.1.3.5|MetaCyc:UDP-ARABINOSE-4-EPIMERASE-RXN UDParabinose 4-epimerase activity|UDP-D-xylose 4-epimerase activity|uridine 5'-diphosphate-D-xylose 4-epimerase activity|UDP-L-arabinose 4-epimerase activity|UDP-D-xylose-4-epimerase activity|UDP arabinose epimerase activity|uridine diphosphoarabinose epimerase activity Catalysis of the reaction: UDP-L-arabinose = UDP-alpha-D-xylose. CHEBI:52682 butane-1,2-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52682 CHEBI:37067 purine ribonucleoside 5'-tetraphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37067 GO:1990475 synaptic vesicle, recycling pool biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990475 recycling pool of synaptic vesicles A synaptic vesicle belonging to the pool that repopulate vacancies within the readily releasable pool (RRP) of synaptic vesicles, and require more significant stimuli than the RRP in order to release neurotransmitter; about 10-15% of the total number of synaptic vesicles at a resting terminal bouton are in this state. CHEBI:76647 (5Z,8Z,11Z,14Z)-icosatetraenedioate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76647 GO:1990476 synaptic vesicle, resting pool biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990476 resting pool of synaptic vesicles|reserve pool of synaptic vesicles A synaptic vesicle belonging to the pool that remain unreleased even after prolonged stimulation causes a saturating degree of vesicular turnover. 50-80% of the total number of synaptic vesicles at a resting terminal bouton are in this pool. GO:1990477 NURS complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990477 MTREC complex|Mtl1-Red1 core complex The nuclear RNA silencing (NURS) complex is a protein complex formed by an RNA binding protein Red1, an RNA helicase Mtl1, Red5, Rmn1, Iss10/Pir1, and Ars2/Pir2. This complex is required for the recruitment of the nuclear exosome to Mmi1 nuclear focus. It is likely related to the human CBCN complex. This complex is also known as MTREC. CHEBI:76645 20-oxoarachidonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76645 GO:1990478 response to ultrasound biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990478 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultrasonic stimulus. CHEBI:76646 (2E,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76646 GO:1990471 piRNA uni-strand cluster binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990471 Interacting selectively and non-covalently with uni-strand piRNA clusters, double-stranded DNA regions that give rise to PIWI-interacting RNAs (piRNAs) that map predominantly to only one strand and exhibit hallmarks of canonical Pol II transcription. Uni-strand piRNA clusters are found in many taxa. GO:1990472 piRNA dual-strand cluster binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990472 Interacting selectively and non-covalently with dual-strand piRNA clusters, double-stranded DNA regions that give rise to PIWI-interacting RNAs (piRNAs) where piRNAs originate from both DNA strands via noncanonical transcription. GO:1990473 ciliary targeting signal binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990473 CTS binding Interacting selectively and non-covalently with a ciliary targeting sequence, a specific peptide sequence that acts as a signal to localize a membrane protein to the ciliary membrane. GO:1990474 synaptic vesicle, readily releasable pool biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990474 readily releasable pool of synaptic vesicles|RRP A synaptic vesicle belonging to the pool of vesicles that are the first to be released as a result of chemical or electrical stimulation e.g. by an action potential, have the highest presynaptic membrane fusion probability and correspond to about 1% of the total number of synaptic vesicles at a resting terminal bouton. GO:1990470 piRNA cluster binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990470 Interacting selectively and non-covalently with piRNA clusters, double-stranded DNA regions that give rise to PIWI-interacting RNAs (piRNAs). CHEBI:62002 galactosyl-(glucosyl)2-(heptosyl)3-(KDO)2-lipid A-bisphosphate(10-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62002 CHEBI:62003 galactosyl-(glucosyl)3-(heptosyl)3-(KDO)2-lipid A-bisphosphate(10-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62003 CHEBI:62000 glucosyl-heptosyl-(phosphonatoheptosyl)2-(KDO)2-lipid A(10-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62000 CHEBI:62001 galactosyl-glucosyl-heptosyl-(phosphonatoheptosyl)2-(KDO)2-lipid A(10-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62001 CHEBI:62006 maltopentaose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62006 CHEBI:62007 maltohexaose hexasaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62007 CHEBI:62004 lipid A-core(10-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62004 CHEBI:62009 maltoheptaose heptasaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62009 CHEBI:76640 (3R,8Z,11Z,14Z,17Z)-3-hydroxyicosatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76640 CL:0000081 blood cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000081 A cell found predominately in the blood. GO:1990479 obsolete response to lipoic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990479 response to 5-(1,2-dithiolan-3-yl)pentanoic acid OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoic acid stimulus. CL:0000082 epithelial cell of lung biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000082 lung epithelial cell An epithelial cell of the lung. CHEBI:76643 (2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76643 CL:0000083 epithelial cell of pancreas biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000083 pancreas epithelial cell|pancreatic epithelial cell An epithelial cell of the pancreas. CHEBI:76644 (3R,9Z,12Z,15Z,18Z,21Z)-3-hydroxytetracosapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76644 CL:0000084 T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000084 T-lymphocyte|T lymphocyte|mature T cell|immature T cell|T-cell A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex. CHEBI:76641 (2E,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76641 CHEBI:76642 (3R,7Z,10Z,13Z,16Z,19Z)-3-hydroxydocosapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76642 CHEBI:76658 (2E,17Z,20Z,23Z,26Z,29Z)-dotriacontahexaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76658 GO:1990486 anaerobic fatty acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990486 anaerobic fatty acid degradation The chemical reactions and pathways resulting in the breakdown of a fatty acid in the absence of oxygen. A fatty acid is any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes. GO:1990487 anaerobic lignin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990487 anaerobic lignin degradation The chemical reactions and pathways resulting in the breakdown of lignin in the absence of oxygen. Lignin is a class of polymers of phenylpropanoid units. CHEBI:76659 (3R,19Z,22Z,25Z,28Z,31Z)-3-hydroxytetratriacontapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76659 GO:1990488 anaerobic cellulose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990488 anaerobic cellulose degradation The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, in absence of oxygen. CHEBI:76656 (2E,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76656 GO:1990489 anaerobic pectin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990489 anaerobic pectin degradation The chemical reactions and pathways resulting in the breakdown of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues, in the absence of oxygen. CHEBI:76657 (3R,17Z,20Z,23Z,26Z,29Z)-3-hydroxydotriacontapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76657 GO:1990482 sphingolipid alpha-glucuronosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990482 inositol phosphorylceramide glucuronosyltransferase activity Catalysis of the reaction: UDP-glucuronate + inositol phosphorylceramide (IPC) = UDP + GlcA-IPC. GO:1990483 Clr6 histone deacetylase complex I'' biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990483 A histone deacetylase complex involved in chromatin organization. In Schizosaccharomyces pombe this complex consists of Clr6, Nts1, Mug165, and Png3. GO:1990484 aerobic lactate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990484 aerobic lactic acid catabolic process The chemical reactions and pathways resulting in the breakdown of lactate (2-hydroxypropanoic acid) in the presence of oxygen. GO:1990485 anaerobic lactate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990485 anaerobic lactic acid catabolic process The chemical reactions and pathways resulting in the breakdown of lactate (2-hydroxypropanoic acid) in the absence of oxygen. CHEBI:62010 maltoheptaose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62010 GO:1990480 obsolete geranyl diphosphate synthase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990480 OBSOLETE. Catalyzes the condensation of dimethylallyl diphosphate and isopentenyl diphosphate to geranyl diphosphate, the key precursor of monoterpene biosynthesis. GO:1990481 mRNA pseudouridine synthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990481 mRNA pseudouridylation The intramolecular conversion of uridine to pseudouridine in an mRNA molecule. CHEBI:62013 glycerol 1-phosphoserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62013 CHEBI:62014 cis-tetradec-3-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62014 CHEBI:62011 4-carboxy-2-hydroxymuconate semialdehyde hemiacetal biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62011 CHEBI:62012 5-deoxy-D-ribose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62012 CHEBI:62017 glucosyl-heptosyl-4-phosphoheptosyl-(KDO)2-lipid A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62017 CL:0000097 mast cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000097 histaminocyte|mastocyte|labrocyte|tissue basophil A cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. Progenitors leave bone marrow and mature in connective and mucosal tissue. Mature mast cells are found in all tissues, except the bloodstream. Their phenotype is CD117-high, CD123-negative, CD193-positive, CD200R3-positive, and FceRI-high. Stem-cell factor (KIT-ligand; SCF) is the main controlling signal of their survival and development. CL:0000098 sensory epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000098 neuroepithelial cell A specialized epithelial cell involved in sensory perception. Restricted to special sense organs of the olfactory, gustatory, and vestibulocochlear receptor systems; contain sensory cells surrounded by supportive, non-receptive cells. CHEBI:62015 L-Ala-gamma-D-Glu-meso-Dap-D-Ala biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62015 CL:0000099 interneuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000099 Most generally any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions. CHEBI:62016 glucosyl-(heptosyl)2-(KDO)2-lipid A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62016 CHEBI:76650 (3R,11Z,14Z,17Z,20Z,23Z)-3-hydroxyhexacosapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76650 CHEBI:76651 (2E,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76651 CL:0000092 osteoclast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000092 chondroclast A specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes. This cell has the following markers: tartrate-resistant acid phosphatase type 5-positive, PU.1-positive, c-fos-positive, nuclear factor NF-kappa-B p100 subunit-positive, tumor necrosis factor receptor superfamily member 11A-positive and macrophage colony-stimulating factor 1 receptor-positive. CHEBI:76654 (3R,15Z,18Z,21Z,24Z,27Z)-3-hydroxytriacontapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76654 CL:0000094 granulocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000094 polymorphonuclear leukocyte|granular leucocyte|granular leukocyte A leukocyte with abundant granules in the cytoplasm. CHEBI:76655 EC 2.1.* (C1-transferase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76655 CL:0000095 neuron associated cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000095 CHEBI:76652 (3R,13Z,16Z,19Z,22Z,25Z)-3-hydroxyoctacosapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76652 CHEBI:76653 (2E,13Z,16Z,19Z,22Z,25Z)-octacosahexaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76653 CL:0000096 mature neutrophil biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000096 poly|polynuclear neutrophilic leucocyte|polymorphonuclear neutrophil|polymorphonuclear leucocyte|polynuclear neutrophilic leukocyte|mature neutrophil leucocyte|mature neutrocyte|PMN|polymorphonuclear leukocyte|mature neutrophilic leucocyte|mature neutrophil leukocyte|mature neutrophilic leukocyte A fully differentiated neutrophil, a granular leukocyte having a nucleus with three to five lobes connected by slender threads, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes. They are produced in bone marrow at a rate of 5e10-10e10/day and have a half-life of 6-8 hours. Neutrophils are CD15-positive, CD16-positive, CD32-positive, CD43-positive, CD181-positive, and CD182-positive. GO:1990497 regulation of cytoplasmic translation in response to stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990497 Modulation of the frequency, rate or extent of cytoplasmic translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). CHEBI:76669 (3R,23Z,26Z,29Z,32Z,35Z)-3-hydroxyoctatriacontapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76669 GO:1990498 mitotic spindle microtubule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990498 Any microtubule that is part of a mitotic spindle; anchored at one spindle pole. GO:1990499 raps-insc complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990499 IntAct:EBI-9674411 Rapsynoid-Inscuteable complex|partner of inscuteable-inscuteable complex Protein complex required for the asymmetric division of neuroblasts in Drosophila. Coordinates asymmetric localization of cell fate determinants with orientation of the mitotic spindle resulting in different daughter cells upon division. Localizes at the apical cortex of the neuroblast: Raps maintains, but does not initiate, Insc apically, while Insc segregates Raps asymmetrically. Complex appears to be conserved in mammals (composed of INSC and GPSM1 or GPSM2). CHEBI:76667 (2E,21Z,24Z,27Z,30Z,33Z)-hexatriacontahexaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76667 CHEBI:76668 EC 2.7.* (P-containing group transferase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76668 GO:1990493 obsolete cyclin H-CDK7 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990493 cyclin H-CDK7 complex OBSOLETE. A protein complex consisting of cyclin H and cyclin-dependent kinase 7 (CDK7). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. GO:1990494 obsolete regulation of mitotic cytokinesis, actomyosin contractile ring assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990494 regulation of mitotic cytokinesis, actomyosin contractile ring assembly OBSOLETE. Any process that modulates the frequency, rate or extent of mitotic cytokinesis, actomyosin contractile ring assembly. GO:1990495 obsolete actin filament organization involved in mitotic cytokinetic actomyosin contractile ring assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990495 actin filament organization involved in mitotic cytokinetic actomyosin contractile ring assembly OBSOLETE. An actin filament organization process that contributes to actomyosin contractile ring assembly during mitotic cytokinesis. GO:1990496 obsolete regulation of actin filament organization involved in mitotic cytokinetic actomyosin contractile ring assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990496 regulation of actin filament organization involved in mitotic cytokinetic actomyosin contractile ring assembly OBSOLETE. An actin filament organization process that contributes to regulation of actomyosin contractile ring assembly during mitotic cytokinesis. GO:1990490 archaeal proton-transporting A-type ATPase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990490 archaeal A-type ATPase protein complex|A-type ATPase protein complex A large proton-transporting two-sector ATPase protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane and is found in Archaea. GO:1990491 methane biosynthetic process from methanol and hydrogen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990491 methanogenesis from methanol and hydrogen|methane biosynthesis from methanol and hydrogen The chemical reactions and pathways resulting in the formation of methane from methanol and hydrogen. GO:1990492 obsolete mitotic cell cycle checkpoint inhibiting CAR assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990492 Mad2-dependent mitotic cell cycle checkpoint|mitotic cell cycle checkpoint inhibiting cytokinetic actomyosin ring assembly OBSOLETE. A Mad2-dependent mitotic cell cycle checkpoint which delays cytokinetic actinomycin ring assembly if there is a delay in early M-phase. CL:0000064 ciliated cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000064 A cell that has a filiform extrusion of the cell surface. CL:0000066 epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000066 epitheliocyte A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina. CL:0000067 ciliated epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000067 An epithelial cell that has a cilia. CL:0000068 duct epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000068 An epithelial cell that is part of a duct. CL:0000069 branched duct epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000069 CHEBI:76661 EC 2.3.* (acyltransferase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76661 CHEBI:76662 EC 2.4.* (glycosyltransferase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76662 CHEBI:76660 EC 2.2.* (aldehyde or ketone transferase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76660 CHEBI:76665 EC 2.6.* (nitrogenous group transferase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76665 CL:0000060 odontoblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000060 Skeletogenic cell that secretes dentine matrix, is derived from the odontogenic papilla, and develops from a preodontoblast cell. CHEBI:76666 (3R,21Z,24Z,27Z,30Z,33Z)-3-hydroxyhexatriacontapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76666 CHEBI:76663 EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76663 CL:0000062 osteoblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000062 Skeletogenic cell that secretes osteoid, is capable of producing mineralized (hydroxyapatite) matrix, is located adjacent to or within osteoid tissue, and arises from the transformation of a preosteoblast cell. CHEBI:76664 (2E,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76664 CHEBI:76678 (2E,10Z,13Z,16Z,19Z,22Z,25Z)-octacosaheptaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76678 CHEBI:76679 (3R,12Z,15Z,18Z,21Z,24Z,27Z)-3-hydroxytriacontahexaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76679 CHEBI:62031 polar amino acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62031 CL:0000075 columnar/cuboidal epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000075 A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube. CL:0000076 squamous epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000076 CHEBI:62037 beta-D-Manp-(1->2)-D-Manp biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62037 CL:0000077 mesothelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000077 mesotheliocyte A flattened epithelial cell of mesenchymal origin that lines the serous cavity. CL:0000079 stratified epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000079 CHEBI:76672 (3R,8Z,11Z,14Z,17Z,20Z,23Z)-hydroxyhexacosahexaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76672 CHEBI:76673 (2E,8Z,11Z,14Z,17Z,20Z,23Z)-hexacosaheptaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76673 CHEBI:76670 (2E,23Z,26Z,29Z,32Z,35Z)-octatriacontahexaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76670 CHEBI:76671 (23Z,26Z,29Z,32Z,35Z)-octatriacontapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76671 CL:0000071 blood vessel endothelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000071 cuboidal endothelial cell of vascular tree An endothelial cell that lines the vasculature. CHEBI:76675 (3R,10Z,13Z,16Z,19Z,22Z,25Z)-3-hydroxyoctacosahexaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76675 GO:1990431 priRNA 3'-end processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990431 primal small RNA 3'-end processing|priRNA 3' end processing The process of forming the mature 3' end of a priRNA molecule. GO:1990432 siRNA 3'-end processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990432 siRNA 3' end processing|small interfering RNA 3'-end processing The process of forming the mature 3' end of a siRNA molecule. GO:1990433 CSL-Notch-Mastermind transcription factor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990433 IntAct:EBI-9636287 CSL-NotchIC-MASTERMIND complex A DNA-binding transcription factor complex consisting of CSL and mastermind proteins in complex with the cleaved, intracellular domain of Notch. It is required for both repression and activation of Notch target genes. GO:1990434 lower tip-link density biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990434 LTLD An electron-dense plaque at the lower end of a stereocilia tip link that provides the anchor in the stereocilia membrane at the tip of the stereocilium from which the tip link rises. GO:1990430 extracellular matrix protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990430 Interacting selectively and non-covalently with a protein that is part of an extracellular matrix. CHEBI:62041 P(1),P(5)-bis(5'-adenosyl) pentaphosphate(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62041 CHEBI:86013 2-hydroxytestosterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86013 CHEBI:62046 biotinate sulfoxide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62046 CHEBI:86014 3,22-dioxochol-4-en-24-oyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86014 CHEBI:62047 (S)-carnitinyl-CoA(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62047 CHEBI:86016 GDP-N,N'-diacetylbacillosamine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86016 CL:0000042 neutrophilic myeloblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000042 neutrophilic granuloblast A myeloblast committed to the neutrophil lineage. This cell type is GATA-1 positive, C/EBPa-positive, AML-1-positive, c-myb-positive and has low expression of PU.1 transcription factor. CHEBI:86018 3beta-hydroxychol-5-en-24-oyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86018 CL:0000043 mature basophil biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000043 mature basophil leucocyte|polymorphonuclear leucocyte|mature basophil leukocyte|polymorphonuclear leukocyte A fully differentiated basophil, a granular leukocyte with an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation. CHEBI:86019 S-[(2E,6E)-farnesyl]-L-cysteine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86019 CHEBI:62048 haloacyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62048 CHEBI:62049 acyl donor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62049 CL:0000047 neuronal stem cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000047 NSC|neural stem cell Neural stem cell is characterized as an undifferentiated cell that originates from the neuroectoderm and has the capacity both to perpetually self-renew without differentiating and to generate multiple types of lineage-restricted progenitors. CHEBI:76680 (2E,12Z,15Z,18Z,21Z,24Z,27Z)-triacontaheptaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76680 CL:0000048 multi fate stem cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000048 multifate stem cell|multi-fate stem cell|multipotent cell|multipotent stem cell A stem cell that can give rise to multiple lineages of cells. CL:0000049 common myeloid progenitor biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000049 common myeloid precursor|colony forming unit granulocyte, erythrocyte, macrophage, and megakaryocyte|CFU-GEMM|CFU-S|pluripotent stem cell (bone marrow)|multipotential myeloid stem cell|myeloid stem cell|CMP A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages. GO:1990439 MAP kinase serine/threonine phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990439 Catalysis of the reaction: MAP kinase threonine phosphate + H2O = MAP kinase threonine + phosphate and MAP kinase serine phosphate + H2O = MAP kinase serine + phosphate. CHEBI:76683 (2E,14Z,17Z,20Z,23Z,26Z,29Z)-dotriacontaheptaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76683 PR:000000017 interferon gamma biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000000017 IFNG|immune interferon|IFN-gamma A type II interferon that is a translation product of the human IFNG gene or a 1:1 ortholog thereof. The core domain structure consists of an Interferon gamma domain (Pfam:PF00714) that is four-helical cytokine domain with an additional helix in one of the crossover connections. It is a cytokine produced by lymphocytes activated by specific antigens or mitogens that has important immunoregulatory functions. CHEBI:76684 (3R,16Z,19Z,22Z,25Z,28Z,31Z)-3-hydroxytetratriacontahexaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76684 PR:000000019 mitogen-activated protein kinase biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000000019 kinase-related transforming protein|MAPK A protein that is a serine/threonine-specific protein kinase that responds to extracellular stimuli (mitogens) and regulates cellular activities such as gene expression, mitosis, differentiation, and cell survival/apoptosis. The activated form phosphorylates target substrates on Ser or Thr residues followed by a proline. A distinguishing feature is the conserved sequence TxY. CHEBI:76682 (3R,14Z,17Z,20Z,23Z,26Z,29Z)-3-hydroxydotriacontahexaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76682 GO:1990435 upper tip-link density biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990435 UTLD An electron-dense plaque at the upper end of a stereocilia tip link that provides the anchor in the stereocilia membrane on the side of the stereocilium where the tip link ends. CHEBI:76687 (2E,18Z,21Z,24Z,27Z,30Z,33Z)-hexatriacontaheptaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76687 CHEBI:76688 (18Z,21Z,24Z,27Z,30Z,33Z)-hexatriacontahexaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76688 GO:1990436 obsolete MAPK cascade involved in oxidative stress signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990436 MAPK cascade involved in oxidative stress signaling pathway OBSOLETE. A series of molecular signals in which a MAP kinase cascade activated by oxidative stress relays one or more of the signals, MAP kinase cascades involve at least three protein kinase activities and culminate in the phosphorylation and activation of a MAP kinase. Just FYI in pombe the osmotic stress and oxidative stress MAPK cascade involve many of the same proteins, but the pathways are slightly different, therefore Im req this term. CL:0000040 monoblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000040 colony forming unit monocyte|CFU-M|colony forming unit macrophage|monocyte stem cell A myeloid progenitor cell committed to the monocyte lineage. This cell is CD11b-positive, has basophilic cytoplasm, euchromatin, and the presence of a nucleolus. GO:1990437 snRNA 2'-O-methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990437 The posttranscriptional addition of a methyl group to the 2' oxygen atom of a nucleotide residue in an snRNA molecule. CHEBI:76685 (2E,16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontaheptaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76685 GO:1990438 U6 2'-O-snRNA methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990438 The posttranscriptional addition a methyl group to the 2'-oxygen atom of a nucleotide residue in an U6 snRNA molecule. CHEBI:76686 (3R,18Z,21Z,24Z,27Z,30Z,33Z)-3-hydroxyhexatriacontahexaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76686 GO:1990442 intrinsic apoptotic signaling pathway in response to nitrosative stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990442 nitrosative stress-induced apoptosis|nitrosative stress-induced intrinsic apoptotic signaling pathway A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to nitrosative stress; a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions. GO:1990443 peptidyl-threonine autophosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990443 The phosphorylation by a protein of one or more of its own threonine amino acid residues, or a threonine residue on an identical protein. GO:1990444 F-box domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990444 Interacting selectively and non-covalently with an F-box domain of a protein. GO:1990445 obsolete Multiciliate cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990445 Multiciliate cell differentiation OBSOLETE. The process in which a relatively unspecialized cell acquires features of a multiciliated cell, a specialized epithelial cell type that extends anywhere from 150 to 200 motile cilia per cell in order to produce a vigorous fluid flow critical to human health in several organ systems. GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990440 ER stress-induced upregulation of transcription|up-regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress|upregulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress|upregulation of Pol II transcription induced by ER stress|stimulation of transcription from RNA polymerase II promoter in response to ER stress|activation of transcription from RNA polymerase II promoter in response to ER stress|up-regulation of transcription induced by ER stress Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an endoplasmic reticulum stress. GO:1990441 negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990441 repression of transcription from RNA polymerase II promoter under ER stress|ER stress-induced negative regulation of transcription from RNA polymerase II promoter|inhibition of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress|down regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress|negative regulation of transcription from RNA polymerase II promoter in response to ER stress|down-regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress|reduction of transcription from RNA polymerase II promoter under ER stress|suppression of transcription from RNA polymerase II promoter under ER stress Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an endoplasmic reticulum stress. CHEBI:62055 deoxy oligosaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62055 CL:0000055 non-terminally differentiated cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000055 blast cell A precursor cell with a limited number of potential fates. CL:0000056 myoblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000056 A cell that is commited to differentiating into a muscle cell. Embryonic myoblasts develop from the mesoderm. They undergo proliferation, migrate to their various sites, and then differentiate into the appropriate form of myocytes. Myoblasts also occur as transient populations of cells in muscles undergoing repair. CL:0000057 fibroblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000057 A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped. CL:0000058 chondroblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000058 chrondoplast Skeletogenic cell that is typically non-terminally differentiated, secretes an avascular, GAG rich matrix; is not buried in cartilage tissue matrix, retains the ability to divide, located adjacent to cartilage tissue (including within the perichondrium), and develops from prechondroblast (and thus prechondrogenic) cell. CL:0000059 ameloblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000059 amelocyte|enamel secreting cell Skeletogenic cell that produces enamel, overlies the odontogenic papilla, and arises from the differentiation of a preameloblast cell. PR:000000028 small GTPase biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000000028 A protein with a core domain composition consisting of a Ras family domain (Pfam:PF00071). The small GTPases are monomeric G-proteins which function as GDP/GTP-regulated molecular switches. CHEBI:76695 EC 5.4.* (intramolecular transferase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76695 GO:1990446 U1 snRNP binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990446 Interacting selectively and non-covalently with any part of a U1 small nuclear ribonucleoprotein particle. CL:0000050 megakaryocyte-erythroid progenitor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000050 colony forming unit erythroid megakaryocyte|CFU-EM|megakaryocyte/erythroid progenitor cell|MEP|megakaryocyte/erythrocyte progenitor|CFU-MegE|Meg/E progenitor A progenitor cell committed to the megakaryocyte and erythroid lineages. GO:1990447 U2 snRNP binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990447 Interacting selectively and non-covalently with any part of a U2 small nuclear ribonucleoprotein particle. CL:0000051 common lymphoid progenitor biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000051 common lymphocyte precursor|lymphoid stem cell|CLP|ELP|common lymphoid precursor|common lymphocyte progenitor|early lymphocyte progenitor|lymphopoietic stem cell|committed lymphopoietic stem cell A oligopotent progenitor cell committed to the lymphoid lineage. GO:1990448 exon-exon junction complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990448 EJC binding Interacting selectively and non-covalently with an exon-exon junction complex, a protein complex deposited by the spliceosome upstream of messenger RNA exon-exon junctions. The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay. GO:1990449 obsolete amylin receptor biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990449 IntAct:EBI-9685417|IntAct:EBI-9685439|IntAct:EBI-9008682 CALCR-RAMP2 receptor|CALCR-RAMP3 receptor|AMY1 receptor|AMY2 receptor|AMY3 receptor|amylin receptor|CALCR-RAMP1 receptor OBSOLETE. A G protein-coupled signalling receptor complex consisting of the calcitonin receptor and a receptor activity-modifying protein (RAMP). Amylin is produced in beta-islet cells of the pancreas. It is implicated in selective inhibition of insulin-stimulated glucose utilization and glycogen deposition in muscle, gastric emptying, gastric acid secretion, postprandial glucagon secretion and food intake and aids weight loss. CHEBI:76697 EC 5.99.* (other isomerases) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76697 GO:1990453 nucleosome disassembly/reassembly complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990453 IntAct:EBI-9682603 eaf5/7/3 complex A protein complex involved in the disassembly and subsequent reassembly of nucleosomes. It associates with the coding region of transcriptionally active genes where it interacts with the RNA polymerase II and affects its processivity during co-transcriptional RNA processing and maturation. It exists as a functionally independent part of the NuA4 complex. GO:1990454 L-type voltage-gated calcium channel complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990454 cardiac muscle L-type voltage-gated calcium channel complex|skeletal muscle L-type voltage-gated calcium channel complex A type of voltage-dependent calcium channel responsible for excitation-contraction coupling of skeletal, smooth, and cardiac muscle. 'L' stands for 'long-lasting' referring to the length of activation. GO:1990455 PTEN phosphatase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990455 IntAct:EBI-9637224|IntAct:EBI-9637198 phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN homodimer|phosphatase and tensin homolog|phosphatase and tensin homolog deleted on chromosome ten homodimer A phospholipid phosphatase complex that catalyses the hydrolysis of the second messenger PtdIns (3,4,5)P3. Will also dephosphorylate PtdIns(3,4)P2, PtdIns3P, and Ins(1,3,4,5)P4. Dimerization is critical for its lipid phosphatase function. GO:1990456 mitochondrion-endoplasmic reticulum membrane tethering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990456 mitochondrion-endoplasmic reticulum tethering|mitochondrion-ER tethering|mitochondrion-ER membrane tethering|mitochondrion-ER attachment|mitochondrion-endoplasmic reticulum attachment The attachment of a mitochondrion and an endoplasmic reticulum via molecular tethers that physically bridge their respective membranes and attach them to each other. The tethering may facilitate exchange of metabolites between the organelles. GO:1990450 linear polyubiquitin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990450 M1-linked ubiquitin chain binding Interacting selectively and non-covalently with a linear polymer of ubiquitin. Linear ubiquitin polymers are formed by linking the amino-terminal methionine (M1) of one ubiquitin molecule to the carboxy-terminal glycine (G76) of the next. GO:1990451 cellular stress response to acidic pH biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990451 cellular stress response to acidity Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in the homeostasis of organismal or cellular pH (with pH < 7). pH is a measure of the acidity or basicity of an aqueous solution. GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990452 Parkin-HSel-10-Cullin-1 complex|Parkin/Cul1/F-box protein complex|Park2-FBXW7-Cul1 complex|Parkin-FBXW7-Cul1 protein complex|PRKN-FBXW7-Cul1 complex A ubiquitin ligase complex containing Parkin (PARK2), the F-box protein FBXW7 (also called SEL-10) and a cullin from the Cul1 subfamily; substrate specificity is conferred by the F-box protein. CHEBI:62064 butane-2,3-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62064 CL:0000029 neuron neural crest derived biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000029 CHEBI:62065 chondroitin 6'-sulfate anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62065 CHEBI:62069 phaseic acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62069 CHEBI:86037 3beta-hydroxychola-5,22-dien-24-oyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86037 CL:0000020 spermatogonium biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000020 An euploid male germ cell of an early stage of spermatogenesis. CL:0000021 female germ cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000021 Female germ cell is a germ cell that supports female gamete production. CL:0000022 female germ line stem cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000022 CL:0000023 oocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000023 oogonium A female germ cell that has entered meiosis. CL:0000024 oogonial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000024 An undifferentiated germ cell that proliferates rapidly and gives rise to oocytes. CL:0000025 egg cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000025 ovum|mature oocyte A female gamete where meiosis has progressed to metaphase II and is able to participate in fertilization. CL:0000026 invertebrate nurse cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000026 nurse cell A germline cell that contributes to the development of the oocyte by transferring cytoplasm directly to oocyte. CL:0000027 smooth muscle cell neural crest derived biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000027 A smooth muscle cell derived from the neural crest. GO:1990457 pexophagosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990457 A membrane-bounded intracellular vesicle involved in the degradation of peroxisome by macropexophagy. GO:1990458 lipooligosaccharide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990458 LOS binding|endotoxin binding Interacting selectively and non-covalently with lipooligosaccharide. Lipooligosaccharides (LOSs) are the major glycolipids expressed on mucosal Gram-negative bacteria. GO:1990459 transferrin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990459 Interacting selectively and non-covalently with the transferrin receptor. GO:1990464 D-2-hydroxyacid dehydrogenase (quinone) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990464 D-lactate dehydrogenase (quinone) activity|(R)-2-hydroxy acid dehydrogenase activity|D-lactate:quinone oxidoreductase activity|(R)-2-hydroxyacid:quinone oxidoreductase activity|D-lactate dehydrogenase activity|(R)-2-hydroxy-acid:(acceptor) 2-oxidoreductase activity Catalysis of the reaction: (R)-2-hydroxyacid + a quinone = 2-oxoacid + a quinol. GO:1990465 aldehyde oxygenase (deformylating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990465 RHEA:21440|EC:4.1.99.5 Catalysis of the reaction a long-chain aldehyde + O(2) + 2 NADPH = an alkane + formate + H(2)O + 2 NADP(+). GO:1990466 protein autosumoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990466 protein auto-sumoylation|protein self-sumoylation The sumoylation by a protein of one or more of its own amino acid residues, or residues on an identical protein. GO:1990467 NuA3a histone acetyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990467 A NuA3 complex that catalyzes the acetylation of Histone H3. In S. cerevisiae, this complex consists of Eaf6p, Nto1p, Sas3p, Taf14p, Yng1p and associates with H3K4me3 using Yng1p. GO:1990460 leptin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990460 Interacting selectively and non-covalently with the leptin receptor. CHEBI:62071 2-cis-abscisate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62071 GO:1990461 detoxification of iron ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990461 Any process that reduces or removes the toxicity of iron ion. These include transport of iron away from sensitive areas and to compartments or complexes whose purpose is sequestration of iron ion. CHEBI:62072 naptalamate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62072 GO:1990462 omegasome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990462 Omega-shaped (as in the Greek capital letter) intracellular membrane-bounded organelle enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum. Omegasomes are the first step of the formation of autophagosomes via the phagophore assembly sites. GO:1990463 lateral cortical node biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990463 Skb1-containing cortical node A protein complex that is anchored at the cortical face of the plasma membrane, and contains proteins involved in regulating cell cycle progression. In Schizosaccharomyces pombe, lateral cortical nodes are several megadaltons in size, and contain Slf1, which anchors the complex at the membrane, and the methyltransferase Skb1 in stoichiometric quantities, and may contain other proteins. CHEBI:62070 nalidixic acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62070 CHEBI:62075 (S)-3-hydroxyhexanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62075 CL:0000039 germ line cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000039 A cell that is within the developmental lineage of gametes and is able to pass along its genetic material to offspring. CHEBI:86020 20-methyl-3-oxopregna-4,17-dien-21-oyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86020 CHEBI:86021 S-geranylgeranyl-L-cysteine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86021 CHEBI:62074 3-chloroacrylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62074 CHEBI:86026 tRNA threonylcarbamoyladenosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86026 CHEBI:62077 trans-hex-2-enoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62077 CHEBI:86027 naphthopyran biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86027 CL:0000031 neuroblast (sensu Vertebrata) biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000031 neuroblast A cell that will develop into a neuron often after a migration phase. CHEBI:86028 17-hydroxy-3-oxopregn-4-en-20-carboxy-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86028 CHEBI:86029 liver X receptor agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86029 CL:0000034 stem cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000034 A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. PR:000000001 protein biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000000001 An amino acid chain that is produced de novo by ribosome-mediated translation of a genetically-encoded mRNA. CL:0000035 single fate stem cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000035 unipotential stem cell|unipotent stem cell A stem cell that self-renews as well as give rise to a single mature cell type. CL:0000036 epithelial fate stem cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000036 CL:0000037 hematopoietic stem cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000037 blood forming stem cell|colony forming unit hematopoietic|hemopoietic stem cell|HSC A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119. CL:0000038 erythroid progenitor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000038 erythroid stem cell|CFU-E|BFU-E|blast forming unit erythroid|colony forming unit erythroid|burst forming unit erythroid A progenitor cell committed to the erythroid lineage. PR:000000008 TGF-beta-like cystine-knot cytokine biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000000008 TGF-beta superfamily A protein with a core domain composition consisting of a signal peptide, a variable propeptide region and a Transforming growth factor beta like domain (Pfam:PF00019), which is a cystine-knot domain containing four conserved beta strands, S1-S4, which form two antiparallel beta sheets (SI-S2 and S3-S4) interconnected by three disulfide bridges in a knot-like topology. Cystines [II-V] and [III-VI] form a ring through which the remaining disulfide bond (Cys[I-IV]) penetrates. Insertion of different variable regions into this common motif has given rise to various subclasses of the growth factor cystine-knot domain. GO:1990468 NuA3b histone acetyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990468 A NuA3 complex that catalyzes the acetylation of Histone H3. In S. cerevisiae, this complex consists of Eaf6p, Nto1p, Sas3p, Taf14p, Pdp3 and associates with H3K4me3 via Pdp3p. GO:1990469 Rhino-Deadlock-Cutoff Complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990469 IntAct:EBI-9694217 RDC complex|rhi-del-cuff complex Protein complex found in Drosophila consisting of the gene products of cuff, del and rhi. It regulates the licensing of transcription of dual-strand PIWI interacting RNA (piRNA) source loci by binding to dual-strand-cluster chromatin, probably via the H3K9me3-binding activity of Rhi. Rhi binding brings the putative termination cofactor Cuff in close proximity to the nascent piRNA precursor transcript which it appears to protect from degradation. CL:0000030 glioblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000030 GO:1990871 Vma12-Vma22 assembly complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990871 A protein complex that is involved in the assembly of the V-ATPase complex. In the budding yeast Saccharomyces cerevisiae, this complex consists of Vma12p and Vma22p. CHEBI:27636 L-glycol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27636 GO:1990872 obsolete negative regulation of sterol import by negative regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990872 negative regulation of sterol import by upregulation of transcription from RNA polymerase II promoter|negative regulation of sterol import by up regulation of transcription from RNA polymerase II promoter|negative regulation of sterol influx by stimulation of transcription from RNA polymerase II promoter|negative regulation of sterol uptake by up regulation of transcription from RNA polymerase II promoter|negative regulation of sterol influx by up-regulation of transcription from RNA polymerase II promoter|negative regulation of sterol influx by upregulation of transcription from RNA polymerase II promoter|negative regulation of sterol uptake by negative regulation of transcription from RNA polymerase II promoter|negative regulation of sterol import by stimulation of transcription from RNA polymerase II promoter|negative regulation of sterol import by up-regulation of transcription from RNA polymerase II promoter|negative regulation of sterol uptake by stimulation of transcription from RNA polymerase II promoter|negative regulation of sterol uptake by activation of transcription from RNA polymerase II promoter|negative regulation of sterol uptake by up-regulation of transcription from RNA polymerase II promoter|negative regulation of sterol import by activation of transcription from RNA polymerase II promoter|negative regulation of sterol import by negative regulation of transcription from Pol II promoter|negative regulation of sterol influx by up regulation of transcription from RNA polymerase II promoter|negative regulation of sterol influx by activation of transcription from RNA polymerase II promoter|negative regulation of sterol uptake by upregulation of transcription from RNA polymerase II promoter|negative regulation of sterol influx by negative regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that decreases the frequency, rate or extent of sterol import, by down regulation of transcription from an RNA polymerase II promoter. GO:1990873 intrinsic component of plasma membrane of cell tip biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990873 The component of the plasma membrane surrounding the cell tip consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the plasma membrane surrounding the cell tip or some other covalently attached group such as a GPI anchor that is similarly embedded in the plasma membrane surrounding the cell tip. CHEBI:27638 cobalt atom biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27638 GO:1990874 vascular associated smooth muscle cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990874 vascular smooth muscle cell proliferation|VSMC proliferation The multiplication or reproduction of vascular smooth muscle cells, resulting in the expansion of a cell population. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels. CHEBI:27639 (E)-2-benzylidenesuccinyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27639 CHEBI:27632 acetophenone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27632 UBERON:0009030 left pulmonary vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009030 Vein that drains left lung and returns blood to the heart. GO:1990870 obsolete protein fibril biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990870 OBSOLETE. A polymer of proteins that form a fine fiber. CHEBI:27630 precorrin-5 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27630 UBERON:0010020 tubotympanic recess epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010020 tubotympanic recess The dorsal portion of the embryonic first endodermal pharyngeal pouch; it develops into the middle ear cavity. UBERON:0010025 dorsal part of pharyngeal pouch 3 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010025 dorsal branchial pouch 3 endoderm|dorsal wing of pharyngeal pouch 3|dorsal pharyngeal pouch 3 endoderm|cranial dorsal aspect of third dorsal pharyngeal pouch|dorsal 3rd branchial pouch|dorsal 3rd arch pharyngeal pouch endoderm|dorsal pharyngeal pouch 3 UBERON:0010026 ventral part of pharyngeal pouch 3 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010026 ventral 3rd branchial pouch|ventral 3rd arch pharyngeal pouch endoderm|caudal ventral aspect of third dorsal pharyngeal pouch|ventral pharyngeal pouch 3|ventral branchial pouch 3 endoderm|ventral wing of pharyngeal pouch 3|ventral pharyngeal pouch 3 endoderm GO:1990879 CST complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990879 IntAct:EBI-8801947|IntAct:EBI-10043724|IntAct:EBI-8801830 Cdc13-Stn1-Ten1 complex|CTC1-OBFC1-TEN1 complex A complex formed by the association of Cdc13 (CTC1 in mammals) with Stn1 in yeast (OBFC1 in mammals) and Ten1 protein (also TEN1 in mammals) with single-stranded telomeric DNA. The CST complex plays a role in telomere protection. UBERON:0009032 right pulmonary vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009032 Vein that drains right lung and returns blood to the heart. UBERON:0009035 renal straight tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009035 straight tubule|kidney straight tubule Any region of a nephron tubule that is straight. Examples: distal convoluted tubule, proximal convoluted tuble. GO:1990875 nucleoplasmic side of nuclear pore biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990875 nucleoplasmic side of nucleopore|nucleoplasmic side of NPC|nucleoplasmic side of nuclear pore complex The side of the nuclear pore complex (NPC) that faces the nucleoplasm. GO:1990876 cytoplasmic side of nuclear pore biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990876 cytoplasmic side of NPC|cytoplasmic side of nucleopore|cytoplasmic side of nuclear pore complex The side of the nuclear pore complex (NPC) that faces the cytoplasm. GO:1990877 Lst4-Lst7 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990877 FNIP-Folliculin RagC/D GAP complex|FLCN-FNIP2 complex|FLCN-FNIP1 complex A heterodimeric complex that functions as a GTPase-Activating Protein (GAP) Complex for members of the Rag family of GTPases. In the budding yeast, this complex contains Lst4 and Lst7, while the orthologous mammalian complex contains Follicular (FLCN) and either follicular interaction protein 1 (FNIP1) or FNIP2. UBERON:0009039 lymph node germinal center biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009039 germinal center|lymph node nodule|lymph node activated zone|lymph node central zone|lymph node light zone A germinal center that is located in a lymph node GO:1990878 cellular response to gastrin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990878 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gastrin stimulus. GO:1990882 rRNA acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990882 The modification of rRNA structure by addition of an acetyl group to rRNA. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid. CHEBI:27647 prostaglandin G2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27647 GO:1990883 rRNA cytidine N-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990883 Catalysis of the reaction: acetyl-CoA + cytidine = CoA + N4-acetylcytidine. The cytidine is within the polynucleotide chain of an rRNA. CHEBI:27648 3-oxohexanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27648 GO:1990884 RNA acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990884 The posttranscriptional addition of one or more acetyl groups to specific residues in an RNA molecule. GO:1990885 obsolete protein serine/threonine kinase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990885 OBSOLETE. Interacting selectively and non-covalently with a protein serine/threonine kinase. CHEBI:27644 chlortetracycline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27644 CHEBI:27645 dTDP-3-dehydro-4,6-dideoxy-alpha-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27645 GO:1990880 cellular detoxification of copper ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990880 Any process that reduces or removes the toxicity of copper ions in a cell. These include transport of copper cations away from sensitive areas and to compartments or complexes whose purpose is sequestration. GO:1990881 obsolete negative regulation of transcription from RNA polymerase II promoter in response to DNA damage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990881 down-regulation of transcription from RNA polymerase II promoter in response to DNA damage|inhibition of transcription from RNA polymerase II promoter in response to DNA damage|down regulation of transcription from RNA polymerase II promoter in response to DNA damage|downregulation of transcription from RNA polymerase II promoter in response to DNA damage OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of DNA damage. UBERON:0010011 collection of basal ganglia biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010011 set of basal ganglia|cerebral nuclei|subcortical nuclei|set of basal nuclei|basal nuclei (basal ganglia)|basal ganglia set|basal nuclei|basal ganglia Subcortical masses of gray matter in the forebrain and midbrain that are richly interconnected and so viewed as a functional system. The nuclei usually included are the caudate nucleus (caudoputamen in rodents), putamen, globus pallidus, substantia nigra (pars compacta and pars reticulata) and the subthalamic nucleus. Some also include the nucleus accumbens and ventral pallidum. CHEBI:27641 cycloheximide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27641 CHEBI:27642 methyl tert-butyl ether biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27642 UBERON:0010009 aggregate regional part of brain biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010009 set of nuclei of neuraxis A regional part of brain consisting of multiple brain regions that are not related through a simple volummetric part of hierarchy, e.g., basal ganglia[NIF]. GO:1990886 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990886 GO:1990887 2-polyprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990887 Catalysis of the reaction: 2-polyprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol + S-adenosyl-L-methionine = ubiquinol-n + S-adenosyl-L-homocysteine + H+. GO:1990888 2-polyprenyl-6-hydroxyphenol O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990888 Catalysis of the reaction: 2-polyprenyl-6-hydroxyphenol + S-adenosyl-L-methionine = 2-polyprenyl-6-methoxyphenol + S-adenosyl-L-homocysteine + H+. UBERON:0009027 vesical artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009027 vesical arteries|arteria vesicali An artery that supplies blood to the urinary bladder. GO:1990889 H4K20me3 modified histone binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990889 Interacting selectively and non-covalently with a histone H4 in which the lysine residue at position 20 has been modified by trimethylation. GO:1990893 mitotic chromosome centromere condensation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990893 mitotic chromosome condensation at kinetochore The cell cycle process in which centromere chromatin structure is compacted prior to and during mitosis. GO:1990894 obsolete positive regulation of induction of conjugation with cellular fusion by regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990894 OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in positive regulation of induction of conjugation with cellular fusion. GO:1990895 regulation of protein localization to cell cortex of cell tip biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990895 Any process that modulates the frequency, rate or extent of protein localization to cell cortex of cell tip. CHEBI:27616 psoralen biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27616 GO:1990896 protein localization to cell cortex of cell tip biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990896 A process in which a protein is transported to, or maintained in, the cell cortex of the cell tip. CHEBI:27617 monensin A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27617 GO:1990890 netrin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990890 Interacting selectively and non-covalently with a netrin receptor. GO:1990891 mitotic sister chromatid arm separation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990891 The cell cycle process in which sister chromatid arms are physically detached from each other during mitosis. CHEBI:27612 hydantoin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27612 GO:1990892 mitotic chromosome arm condensation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990892 The cell cycle process in which chromosome arm chromatin structure is compacted prior to and during mitosis in eukaryotic cells. CHEBI:27613 amygdalin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27613 UBERON:0010000 multicellular anatomical structure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010000 multicellular structure An anatomical structure that has more than one cell as a part. UBERON:0010001 cell cluster organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010001 A small cluster of cells of various types which form a discrete structure, largely delimited by a morphological boundary and whose components work together to make the whole structure capable of a specific function. UBERON:0009010 periurethral tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009010 Any portion of tissue that surrounds a urethra. GO:1990897 obsolete CTDK-1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990897 OBSOLETE. A protein complex that phosphorylates serine 2 residues in the CTD domain of productively elongating large subunits of DNA-directed RNA polymerase II, holoenzyme. In S. cerevisiae this complex consists of CTK1/CTK2/CTK3, in S. pombe Lsk1/Lsc1/Lsg1. Human CTK1 homologs include CDK12/13. CHEBI:27618 chalcone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27618 GO:1990898 meiotic DNA double-strand break clipping biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990898 The process by which SPO11/Rec12-oligonucleotide complexes are removed from 5' DNA double-strand breaks induced during meiosis. Proteins involved in this process include the MRX/MRN complex and Sae2/Ctp1/RBBP8(CtIP). UBERON:0009015 upper back skin biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009015 A zone of skin that is part of a dorsal thoracic segment of trunk. GO:1990899 meiotic DNA double-strand break resectioning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990899 The process following clipping in double-strand break processing of SPO11 induced breaks, where long-tract single-stranded 3'-end DNA is generated from naked (SPO11 has been removed) 5' ends. CHEBI:27625 alpha-D-glucosamine 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27625 CHEBI:27626 3,4-dehydrothiomorpholine-3-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27626 CHEBI:27628 4-isopropylbenzyl alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27628 CHEBI:27624 prostaglandin B1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27624 GO:1990830 cellular response to leukemia inhibitory factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990830 cellular response to CDF|cellular response to cholinergic differentiation factor Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus. CHEBI:76608 2-iminopropionic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76608 UBERON:0010065 auditory meatus epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010065 UBERON:0010063 tympanic cavity epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010063 UBERON:0010064 open anatomical space biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010064 An anatomical space with at least one opening to another space or the exterior. UBERON:0010069 outer epithelial layer of tympanic membrane biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010069 outer layer of tympanic membrane|outer cuticular layer of tympanic membrane|tympanic membrane external acoustic meatus epithelial component|cuticular layer of tympanic membrane|cuticular stratum of tympanic membrane A portion of the external acoustic meatus epithelium which makes up the outer (cuticular) layer of the tympanic membrane GO:1990839 response to endothelin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990839 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an endothelin stimulus. Endothelin is any of three secretory vasoconstrictive peptides (endothelin-1, -2, -3). GO:1990835 obsolete insulin-like growth factor production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990835 IGF production OBSOLETE. The appearance of an insulin-like growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:1990836 lysosomal matrix biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990836 A matrix composed of supramolecular assemblies of lysosomal enzymes and lipids which forms at a pH of 5.0 within the lysosome. GO:1990837 sequence-specific double-stranded DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990837 sequence-specific dsDNA binding Interacting selectively and non-covalently with double-stranded DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA, e.g. promotor binding or rDNA binding. GO:1990838 poly(U)-specific exoribonuclease activity, producing 3' uridine cyclic phosphate ends biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990838 Catalysis of 3' exonucleolytic cleavage of poly(U), to form poly(U)-N containing a 3' uridine cyclic phosphate (U>P). GO:1990831 cellular response to carcinoembryonic antigen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990831 cellular response to pregnancy specific glycoprotein Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carcinoembryonic antigen stimulus. The carcinoembryonic antigens represent a family of glycoproteins. GO:1990832 slow axonal transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990832 The directed slow movement of non-membranous molecules in nerve cell axons. It is comprised of a Slow Component a (SCa) and a Slow Component b (SCb) which differ in transport rates and protein composition. GO:1990833 clathrin-uncoating ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990833 Catalysis of the reaction: ATP + H2O = ADP + phosphate. Catalysis of the removal of clathrin from vesicle membranes, coupled to the hydrolysis of ATP. GO:1990834 response to odorant biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990834 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an odorant stimulus. An odorant is any substance capable of stimulating the sense of smell. CHEBI:27603 1(F)-alpha-D-galactosylraffinose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27603 CHEBI:76614 3-hydroxyoctadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76614 CHEBI:76615 3,18-dihydroxyoctadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76615 CHEBI:27605 D-psicose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27605 GO:1990840 response to lectin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990840 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lectin stimulus. A lectin is a carbohydrate-binding protein, highly specific for binding sugar moieties. GO:1990841 promoter-specific chromatin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990841 Interacting selectively and non-covalently with a section of chromatin that is associated with gene promoter sequences of DNA. NCBITaxon:1117 Cyanobacteria organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_1117 blue-green bacteria|Cyanophyta|cyanobacteria|Oxygenic photosynthetic bacteria|Cyanophyceae|Oxyphotobacteria|blue-green algae|cyanophytes|Cyanophycota CHEBI:76613 3-hydroxypalmitate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76613 CHEBI:76618 3,12-dihydroxylaurate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76618 CHEBI:76619 omega-methyl fatty acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76619 CHEBI:27601 pteridine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27601 CHEBI:76616 3-hydroxylaurate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76616 CHEBI:76617 EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76617 UBERON:0010052 mucosa of dorsum of tongue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010052 mucosa of dorsal surface of tongue A mucosa that is part of a dorsum of tongue. UBERON:0010053 echolocation organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010053 Any organ that plays a role in the process of echolocation. UBERON:0010059 hypoglossal cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010059 UBERON:0010056 future tongue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010056 A compound organ that has the potential to develop into a tongue. GO:1990846 ribonucleoside-diphosphate reductase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990846 Binds to and stops, prevents or reduces the activity of ribonucleoside-diphosphate reductase. GO:1990847 obsolete peptide pheromone transmembrane export involved in positive regulation of conjugation with cellular fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990847 OBSOLETE. The directed movement of a peptide pheromone across a membrane and out of a cell by a secretion or export pathway used solely for the export of peptide pheromones that contributes to a conjugation process that results in the union of cellular and genetic information from compatible mating types. GO:1990848 obsolete Positive regulation of removal of reactive oxygen species biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990848 OBSOLETE. Any process that increases the frequency, rate or extent of removal of reactive oxygen species in a cell. GO:1990849 maintenance of vacuolar location biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990849 maintenance of vacuolar localization|maintenance of vacuole localization|maintenance of vacuole location Any process in which the vacuole is maintained in a specific location within a cell and prevented from moving elsewhere. GO:1990842 obsolete response to prenatal stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990842 response to PNS OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis in the embryo or fetus during pregnancy. CHEBI:76610 omega-hydroxytetracosanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76610 GO:1990843 subsarcolemmal mitochondrion biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990843 SS mitochondrion|SSM A mitochondrion that occurs adjacent to the sarcolemma in striated muscle cells and responds in distinct ways to physiological triggers. GO:1990844 interfibrillar mitochondrion biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990844 IMF mitochondrion|intermyofibrillar mitochondrion|IFM A mitochondrion that occurs in between fibrils of striated muscle cells and responds in distinct ways to physiological triggers. CHEBI:27609 coproporphyrin III biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27609 GO:1990845 adaptive thermogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990845 The regulated production of heat in response to short term environmental changes, such as stress, diet or reduced temperature. CHEBI:76625 11,12-EET(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76625 GO:1990850 H-gal-GP complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990850 galactose-containing glycoprotein complex|Haemonchus galactose-containing glycoprotein complex A membrane glycoprotein complex with aspartyl proteinase and metalloproteinase activity which is expressed in the gut. An example of this is found in the nematode Haemonchus contortus. CHEBI:76626 (23Z,26Z,29Z,32Z)-octatriacontatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76626 GO:1990851 Wnt-Frizzled-LRP5/6 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990851 Frizzled-LRP5/6 complex|Wnt-induced Frizzled-LRP5/6 complex|WNT-FZD-LRP6 complex|WNT-FZD-LRP5 complex|Fz/Wnt/LRP6 complex|Wnt.Fz.LRP ternary complex|Wnt receptor complex|Wnt-FZD-LRP5/6 trimeric complex A protein complex containing a secreted Wnt protein associated with its receptor, Frizzled (Fz), and co-receptor low density lipoprotein receptor-related protein 5 (LRP5) or LRP6. CHEBI:76623 (2E,23Z,26Z,29Z,32Z)-octatriacontapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76623 GO:1990852 protein transport along microtubule to spindle pole body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990852 The directed movement of a protein along a microtubule to the spindle pole body, mediated by motor proteins. CHEBI:76624 20-HETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76624 UBERON:0009050 nucleus of solitary tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009050 solitary nucleus|solitary tract nucleus|nucleus of the tractus solitarius|nuclei tractus solitarii|nucleus tractus solitarii|nucleus tractus solitarii medullae oblongatae|nucleus tracti solitarii|Geschmackskern@de|nucleus of the solitary tract|nucleus of tractus solitarius|nucleus solitarius|solitary nucleus|solitary nuclear complex A neural nucleus that is part of the solitary tract nuclear complex. The solitary tract and nucleus are structures in the brainstem that carry and receive visceral sensation and taste from the facial (VII), glossopharyngeal (IX) and vagus (X) cranial nerves. [WP,unvetted]. CHEBI:76629 2-lysophosphatidic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76629 CHEBI:76627 19-HETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76627 CHEBI:76628 11-hydroxylaurate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76628 UBERON:0010042 1st arch mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010042 mesenchyme of 1st arch Mesenchyme that is part of a pharyngeal arch 1. UBERON:0010047 oral gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010047 oral cavity gland|buccal gland|mouth gland|oral region gland|gland of oral region|gland of oral opening Gland of the epithelium lining the oral cavity. The most common are the salivary glands. CHEBI:144097 EC 1.4.3.2 (L-amino-acid oxidase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_144097 UBERON:0010045 1st arch maxillary mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010045 mesenchyme of maxillary component|maxillary component mesenchyme|maxillary mesenchyme Mesenchyme that is part of a 1st arch maxillary component. UBERON:0010046 entire pharyngeal arch associated mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010046 entire branchial arch associated mesenchyme|pharyngeal arch associated mesenchyme|associated mesenchyme of pharyngeal region The sum total of mesenchymal tissue in the pharyngeal arch region. Pharyngeal mesenchyme is undifferentiated, loose connective tissue derived mostly from mesoderm, and also contains ectodermally derived neural crest cells. CHEBI:144099 EC 2.6.1.2 (alanine transaminase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_144099 UBERON:0010039 food storage organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010039 An organ of the digestive tract that is capable of retaining and storing food GO:1990857 obsolete APC-Fzr1/Mfr1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990857 OBSOLETE. An anaphase promoting complex bound to an activator in the Fzr1 (human)/Mfr1 (pombe) family. GO:1990858 cellular response to lectin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990858 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lectin stimulus. A lectin is a carbohydrate-binding protein, highly specific for binding sugar moieties. GO:1990859 cellular response to endothelin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990859 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an endothelin stimulus. Endothelin is any of three secretory vasoconstrictive peptides (endothelin-1, -2, -3). GO:1990853 histone H2A SQE motif phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990853 The modification of histone H2A by the addition of an phosphate group to the serine residue in the SQE motif of the histone. CHEBI:76621 (3R,23Z,26Z,29Z,32Z)-3-hydroxyoctatriacontatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76621 GO:1990854 vacuole-ER tethering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990854 vacuole-endoplasmic reticulum tethering|vacuole-endoplasmic reticulum attachment|vacuole-ER attachment The attachment of a lytic vacuole to the endoplasmic reticulum, which may facilitate exchange of metabolites between the organelles. GO:1990855 obsolete myo-inositol import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990855 OBSOLETE. The directed movement of myo-inositol from outside of a cell into the intracellular region of a cell across the plasma membrane. GO:1990856 methionyl-initiator methionine tRNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990856 Interacting selectively and non-covalently with methionine-initator methionine tRNA. GO:1990860 Pho85-Pho80 CDK-cyclin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990860 A cyclin dependent kinase (CDK) complex that contains a kinase subunit and a regulatory cyclin subunit. An example of this complex in budding yeast S. cerevisiae consists of the Pho85 kinase and the Pho80 cyclin. CHEBI:76636 19-HEPE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76636 CHEBI:76637 (3R,11Z,14Z,17Z)-3-hydroxyicosatrienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76637 GO:1990861 Ubp3-Bre5 deubiquitination complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990861 Ubp3-Bre5 ubiquitin protease complex A protein complex that cleaves ubiquitin from specific substrates. In the budding yeast Saccharomyces cerevisiae, this complex consists of Ubp3p and Bre5p. GO:1990862 nuclear membrane complex Bqt3-Bqt4 biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990862 A protein complex that resides in the inner nuclear membrane and anchors telomeres to the nuclear envelope. In fission yeast, it is composed of Bqt3 and Bqt4. CHEBI:76634 17(R),18(S)-EETeTr(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76634 GO:1990863 acinar cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990863 acinic cell proliferation|acinous cell proliferation The multiplication or reproduction of acinar cells, resulting in the expansion of a cell population. An acinar cell is a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini (singular acinus). CHEBI:76635 17(S),18(R)-EETeTr(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76635 CHEBI:76638 (2E,11Z,14Z,17Z)-icosatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76638 UBERON:0009042 prostatic venous plexus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009042 plexus venosus prostaticus|pudendal venous plexus The prostatic veins form a well-marked prostatic plexus which lies partly in the fascial sheath of the prostate and partly between the sheath and the prostatic capsule. It communicates with the pudendal and vesical plexuses. CHEBI:76639 20-HEPE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76639 UBERON:0010032 anterior part of tongue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010032 anterior 2/3 of the tongue|pars anterior dorsi linguae|apex linguae|front of the tongue|anterior two thirds of the tongue|oral part of the tongue|apex of the tongue|anterior 2/3 of tongue|buccal part of the tongue The portion of the tongue in front of the terminal sulcus. At the apex, thin and narrow, it is directed forward against the lingual surfaces of the lower incisor teeth. It is derived primarily from the first pharyngeal arch. UBERON:0010031 6th arch mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010031 pharyngeal arch 6 mesenchyme|6th pharyngeal arch mesenchyme|6th branchial arch mesenchyme Mesenchyme that is part of a pharyngeal arch 6. UBERON:0010027 dorsal part of pharyngeal pouch 4 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010027 dorsal branchial pouch 4 endoderm|dorsal pharyngeal pouch 4 endoderm|dorsal 4th branchial pouch|dorsal pharyngeal pouch 4 UBERON:0010028 ventral part of pharyngeal pouch 4 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010028 ventral 4th branchial pouch|ventral pharyngeal pouch 4 endoderm|ventral pharyngeal pouch 4|ventral branchial pouch 4 endoderm GO:1990868 response to chemokine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990868 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemokine stimulus. GO:1990869 cellular response to chemokine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990869 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemokine stimulus. GO:1990864 response to growth hormone-releasing hormone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990864 response to sermorelin|response to GHRF|response to GRF|response to somatorelin|response to somatocrinin|response to growth hormone-releasing factor|response to somatoliberin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone-releasing hormone stimulus. Growth hormone-releasing hormone regulates the release of growth hormone, as well as some pancreatic proteins, and possibly other proteins. GO:1990865 obsolete response to intermittent hypoxia biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990865 OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an episodic stimulus indicating lowered oxygen tension. CHEBI:76633 17,18-EETeTr(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76633 GO:1990866 obsolete response to sustained hypoxia biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990866 OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sustained stimulus indicating lowered oxygen tension. GO:1990867 response to gastrin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990867 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gastrin stimulus. CHEBI:76631 1-lysophosphatidic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76631 GO:0001532 interleukin-21 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001532 IL-21 receptor activity|IL-21R Combining with interleukin-21 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0001533 cornified envelope biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001533 A type of plasma membrane that has been modified through addition of distinct intracellular and extracellular components, including ceramide, found in cornifying epithelial cells (corneocytes). GO:0001534 radial spoke biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0001534 Wikipedia:Radial_spoke Protein complex that links the outer microtubule doublet of the ciliary or flagellum axoneme with the sheath that surrounds the central pair of microtubules. Composed of a stalk that attaches to each doublet microtubule and a globular structure (spoke head) that projects toward the central pair of microtubules. GO:0001535 radial spoke head biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001535 radial spokehead Protein complex forming part of eukaryotic flagellar apparatus. CHEBI:52678 3-methoxyphenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52678 GO:0001530 lipopolysaccharide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001530 LPS binding|endotoxin binding Interacting selectively and non-covalently with lipopolysaccharide. GO:0001531 interleukin-21 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001531 interleukin-21 receptor ligand|IL-21 Interacting selectively and non-covalently with the interleukin-21 receptor. CHEBI:52679 5-alkylresorcinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52679 GO:1902258 positive regulation of apoptotic process involved in outflow tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902258 up-regulation of apoptosis involved in outflow tract morphogenesis|up-regulation of apoptotic process involved in outflow tract morphogenesis|upregulation of apoptosis involved in outflow tract morphogenesis|upregulation of apoptotic process involved in outflow tract morphogenesis|up regulation of apoptosis involved in outflow tract morphogenesis|positive regulation of apoptosis involved in outflow tract morphogenesis|up regulation of apoptotic process involved in outflow tract morphogenesis|activation of apoptosis involved in outflow tract morphogenesis|activation of apoptotic process involved in outflow tract morphogenesis Any process that activates or increases the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis. GO:1902259 regulation of delayed rectifier potassium channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902259 Any process that modulates the frequency, rate or extent of delayed rectifier potassium channel activity. GO:1902256 regulation of apoptotic process involved in outflow tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902256 regulation of apoptosis involved in outflow tract morphogenesis Any process that modulates the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis. GO:1902257 negative regulation of apoptotic process involved in outflow tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902257 down-regulation of apoptotic process involved in outflow tract morphogenesis|inhibition of apoptosis involved in outflow tract morphogenesis|inhibition of apoptotic process involved in outflow tract morphogenesis|down regulation of apoptosis involved in outflow tract morphogenesis|downregulation of apoptosis involved in outflow tract morphogenesis|down regulation of apoptotic process involved in outflow tract morphogenesis|downregulation of apoptotic process involved in outflow tract morphogenesis|down-regulation of apoptosis involved in outflow tract morphogenesis|negative regulation of apoptosis involved in outflow tract morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis. GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902254 inhibition of signal transduction by p53 class mediator resulting in induction of apoptosis|down-regulation of intrinsic apoptotic signaling pathway by p53 class mediator|down regulation of signal transduction by p53 class mediator resulting in induction of apoptosis|inhibition of intrinsic apoptotic signaling pathway by p53 class mediator|downregulation of signal transduction by p53 class mediator resulting in induction of apoptosis|down-regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|negative regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|down-regulation of signal transduction by p53 class mediator resulting in induction of apoptosis|down regulation of intrinsic apoptotic signaling pathway by p53 class mediator|negative regulation of signal transduction by p53 class mediator resulting in induction of apoptosis|downregulation of intrinsic apoptotic signaling pathway by p53 class mediator|downregulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|down regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|inhibition of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator. GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902255 upregulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|upregulation of signal transduction by p53 class mediator resulting in induction of apoptosis|up-regulation of intrinsic apoptotic signaling pathway by p53 class mediator|up-regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|activation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|up regulation of signal transduction by p53 class mediator resulting in induction of apoptosis|positive regulation of signal transduction by p53 class mediator resulting in induction of apoptosis|upregulation of intrinsic apoptotic signaling pathway by p53 class mediator|positive regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|activation of signal transduction by p53 class mediator resulting in induction of apoptosis|up regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|up regulation of intrinsic apoptotic signaling pathway by p53 class mediator|up-regulation of signal transduction by p53 class mediator resulting in induction of apoptosis|activation of intrinsic apoptotic signaling pathway by p53 class mediator Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator. GO:1902263 apoptotic process involved in embryonic digit morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902263 apoptotic program involved in embryonic digit morphogenesis|programmed cell death by apoptosis involved in embryonic digit morphogenesis|apoptosis involved in embryonic digit morphogenesis|signaling (initiator) caspase activity involved in embryonic digit morphogenesis|type I programmed cell death involved in embryonic digit morphogenesis|apoptotic cell death involved in embryonic digit morphogenesis|apoptotic programmed cell death involved in embryonic digit morphogenesis Any apoptotic process that is involved in embryonic digit morphogenesis. CHEBI:37039 pyrimidine ribonucleoside 5'-diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37039 GO:1902264 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902264 GO:1902261 positive regulation of delayed rectifier potassium channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902261 upregulation of delayed rectifier potassium channel activity|up-regulation of delayed rectifier potassium channel activity|activation of delayed rectifier potassium channel activity|up regulation of delayed rectifier potassium channel activity Any process that activates or increases the frequency, rate or extent of delayed rectifier potassium channel activity. CHEBI:37037 pyrimidine 2'-deoxyribonucleoside 5'-diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37037 GO:1902262 apoptotic process involved in blood vessel morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902262 apoptosis involved in patterning of blood vessels|type I programmed cell death involved in patterning of blood vessels|signaling (initiator) caspase activity involved in patterning of blood vessels|apoptotic cell death involved in patterning of blood vessels|apoptotic programmed cell death involved in patterning of blood vessels|apoptotic program involved in patterning of blood vessels|programmed cell death by apoptosis involved in patterning of blood vessels Any apoptotic process that is involved in blood vessel morphogenesis. CHEBI:37038 purine ribonucleoside 5'-diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37038 GO:1902260 negative regulation of delayed rectifier potassium channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902260 down regulation of delayed rectifier potassium channel activity|inhibition of delayed rectifier potassium channel activity|down-regulation of delayed rectifier potassium channel activity|downregulation of delayed rectifier potassium channel activity Any process that stops, prevents or reduces the frequency, rate or extent of delayed rectifier potassium channel activity. CHEBI:37030 3-oxohexanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37030 GO:0001536 radial spoke stalk biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001536 Globular portion of the radial spoke that projects towards the central pair of microtubules. CHEBI:37035 3-hydroxyhexanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37035 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001537 Reactome:R-HSA-3636919|Reactome:R-HSA-6786034|Reactome:R-HSA-2022063 N-acetylgalactosamine 4-O-sulphotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-acetyl-D-galactosamine = adenosine 3',5'-bisphosphate + N-acetyl-D-galactosamine 4-sulfate. CHEBI:37036 purine 2'-deoxyribonucleoside 5'-diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37036 GO:0001538 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001538 GO:0001539 cilium or flagellum-dependent cell motility biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0001539 ciliary/flagellar motility|ciliary or bacterial-type flagellar motility Cell motility due to movement of eukaryotic cilia or bacterial-type flagella or archaeal-type flagella. CHEBI:37034 O-acetyl-D-homoserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37034 GO:0001543 ovarian follicle rupture biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001543 Disruption of theca cell layer releasing follicular fluid and/or the oocyte. CHEBI:52669 2-amino-4,5-dihydroxy-6-oxo-7-(phosphonooxy)heptanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52669 GO:0001544 initiation of primordial ovarian follicle growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001544 Increase in size of primordial follicles including proliferation and shape changes of granulosa and/or theca cells until oocyte is surrounded by one layer of cuboidal shaped granulosa cells (primary follicle). GO:0001545 primary ovarian follicle growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001545 Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle). GO:0001546 preantral ovarian follicle growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001546 Increase in size of follicles surrounded by two or more layers of granulosa cells up to the onset of antrum formation. GO:0001540 amyloid-beta binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0001540 beta-amyloid binding Interacting selectively and non-covalently with amyloid-beta peptide/protein. CHEBI:37050 3-hydroxybutanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37050 GO:0001541 ovarian follicle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001541 follicular phase The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure. GO:0001542 ovulation from ovarian follicle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001542 The process leading to the rupture of the follicle, releasing the centrally located oocyte into the oviduct. An example of this is found in Mus musculus. CHEBI:52668 1,4-dihydroxy-2-naphthoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52668 GO:1902269 positive regulation of polyamine transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902269 up regulation of polyamine transmembrane transport|activation of polyamine transmembrane transport|up-regulation of polyamine transmembrane transport|upregulation of polyamine transmembrane transport Any process that activates or increases the frequency, rate or extent of polyamine transmembrane transport. GO:1902267 regulation of polyamine transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902267 Any process that modulates the frequency, rate or extent of polyamine transmembrane transport. GO:1902268 negative regulation of polyamine transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902268 down-regulation of polyamine transmembrane transport|inhibition of polyamine transmembrane transport|down regulation of polyamine transmembrane transport|downregulation of polyamine transmembrane transport Any process that stops, prevents or reduces the frequency, rate or extent of polyamine transmembrane transport. GO:1902265 abscisic acid homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902265 2-cis-abscisate homeostasis|ABA homeostasis Any process involved in the maintenance of an internal steady state of abscisic acid within an organism or cell. GO:1902266 cellular abscisic acid homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902266 cellular ABA homeostasis|cellular 2-cis-abscisate homeostasis Any biological process involved in the maintenance of an internal steady state of abscisic acid at the level of the cell. GO:1902274 positive regulation of (R)-carnitine transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902274 up regulation of (R)-carnitine transmembrane transport|activation of (R)-carnitine transmembrane transport|up-regulation of (R)-carnitine transmembrane transport|upregulation of (R)-carnitine transmembrane transport Any process that activates or increases the frequency, rate or extent of (R)-carnitine transmembrane transport. GO:1902275 regulation of chromatin organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902275 regulation of chromatin modification|regulation of establishment or maintenance of chromatin architecture|regulation of chromatin organisation Any process that modulates the frequency, rate or extent of chromatin organization. GO:1902272 regulation of (R)-carnitine transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902272 Any process that modulates the frequency, rate or extent of (R)-carnitine transmembrane transport. GO:1902273 negative regulation of (R)-carnitine transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902273 down regulation of (R)-carnitine transmembrane transport|downregulation of (R)-carnitine transmembrane transport|down-regulation of (R)-carnitine transmembrane transport|inhibition of (R)-carnitine transmembrane transport Any process that stops, prevents or reduces the frequency, rate or extent of (R)-carnitine transmembrane transport. CHEBI:37049 (S)-3-hydroxyhexanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37049 GO:1902270 (R)-carnitine transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902270 The process in which (R)-carnitine is transported across a membrane. GO:1990806 ligand-gated ion channel signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990806 ligand-gated ion channel signalling pathway A series of molecular signals initiated by activation of a ligand-gated ion channel on the surface of a cell. The pathway begins with binding of an extracellular ligand to a ligand-gated ion channel and ends with a molecular function that directly regulates a downstream cellular process, e.g. transcription. GO:1990807 obsolete protein N-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990807 OBSOLETE. Catalysis of the transfer of an acetyl group to a nitrogen atom on the amino acid of a protein. GO:1902271 D3 vitamins binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1902271 Interacting selectively and non-covalently with D3 vitamins. GO:1990808 F-bar domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990808 Interacting selectively and non-covalently with an F-BAR domain of a protein, a domain of about 60 residues that occurs in a wide range of cytoskeletal proteins. GO:1990809 endoplasmic reticulum tubular network membrane organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990809 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) tubular network membrane. GO:1990802 obsolete protein phosphorylation involved in DNA double-strand break processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990802 protein amino acid phosphorylation involved in DNA double-strand break processing OBSOLETE. Any protein phosphorylation that is required for DNA double-strand break processing. CHEBI:37042 purine 2'-deoxyribonucleoside 5'-triphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37042 GO:1990803 obsolete protein phosphorylation involved in protein localization to spindle microtubule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990803 protein phosphorylation involved in protein localization in spindle microtubule|protein phosphorylation involved in protein localisation in spindle microtubule|protein amino acid phosphorylation involved in protein localization in spindle microtubule|protein amino acid phosphorylation involved in protein localisation in spindle microtubule|protein phosphorylation involved in protein localisation to spindle microtubule|protein amino acid phosphorylation involved in protein localization to spindle microtubule|protein amino acid phosphorylation involved in protein localisation to spindle microtubule OBSOLETE. Any protein phosphorylation process involved in localizing a protein to the spindle microtubule. CHEBI:37043 pyrimidine 2'-deoxyribonucleoside 5'-triphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37043 GO:1990804 obsolete protein phosphorylation involved in double-strand break repair via nonhomologous end joining biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990804 protein amino acid phosphorylation involved in double-strand break repair via nonhomologous end joining|protein amino acid phosphorylation involved in NHEJ|protein phosphorylation involved in NHEJ OBSOLETE. Any protein phosphorylation process that is required for double-strand break repair via nonhomologous end joining. CHEBI:37040 C-nucleoside phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37040 GO:1990805 central cylinder biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990805 A scaffolding structure present within the inner region of the ciliary transition zone. The central cylinder lies between the outer doublet and inner singlet microtubules. CHEBI:37041 N-methyl-2-oxoglutaramic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37041 GO:0001547 antral ovarian follicle growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001547 Increase in size of antral follicles due to cell proliferation and/or growth of the antral cavity. CHEBI:37046 p-menth-8-en-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37046 GO:0001548 follicular fluid formation in ovarian follicle antrum biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001548 ovarian follicle antrum/follicular fluid formation|ovarian follicle antrum/follicular fluid biosynthesis The menstrual cycle process that results in the formation of one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells during the various stages of oogenesis. CHEBI:37047 (+)-cis-isopulegone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37047 GO:0001549 cumulus cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001549 ovarian cumulus cell differentiation The process in which a subpopulation of granulosa cells surrounding the oocyte acquires the specialized features of an ovarian cumulus cell. GO:1990800 obsolete meiotic APC-fizzy-related complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990800 OBSOLETE. An anaphase promoting complex bound to a fizzy-related family APC activator that regulates meiotic exit by activating the APC/C to target meiotic cyclins for destruction during meiosis. CHEBI:37044 pyrimidine ribonucleoside 5'-triphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37044 GO:1990801 obsolete protein phosphorylation involved in mitotic spindle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990801 protein phosphorylation involved in spindle assembly involved in mitosis|protein amino acid phosphorylation involved in mitotic spindle assembly|protein amino acid phosphorylation involved in spindle assembly involved in mitosis OBSOLETE. Any protein phosphorylation that is involved in mitotic spindle assembly. CHEBI:37045 purine ribonucleoside 5'-triphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37045 GO:0001510 RNA methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001510 Posttranscriptional addition of a methyl group to either a nucleotide or 2'-O ribose in a polyribonucleotide. Usually uses S-adenosylmethionine as a cofactor. GO:0001511 obsolete fibrillin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001511 fibrillin OBSOLETE. Large glycoprotein that is a calcium binding component of connective tissue microfibrils containing 34 six-cysteine (EGF-like) repeats and five eight-cysteine (TGFbeta-1 binding protein-like) repeats. Defects associated with Marfan syndrome. GO:0001512 dihydronicotinamide riboside quinone reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001512 Reactome:R-HSA-8936519|MetaCyc:1.10.99.2-RXN|EC:1.10.99.2|RHEA:12364 NQO2|NAD(P)H:quinone oxidoreductase 2 activity|quinone reductase 2 activity|ribosyldihydronicotinamide dehydrogenase (quinone) activity|QR2 activity|NAD(P)H:quinone oxidoreductase-2|NQO(2) activity|NRH:quinone oxidoreductase 2 activity|NAD(P)H:quinone oxidoreductase2|N-ribosyldihydronicotinamide dehydrogenase (quinone) activity|1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide:quinone oxidoreductase activity Catalysis of the reaction: 1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide + a quinone = 1-(beta-D-ribofuranosyl)nicotinamide + a hydroquinone. GO:0001513 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001513 CHEBI:27698 vanadium atom biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27698 CHEBI:52656 O-acyltropine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52656 CHEBI:52657 O-acylpseudotropine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52657 CHEBI:27696 prostaglandin D1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27696 GO:1902278 positive regulation of pancreatic amylase secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902278 upregulation of pancreatic amylase secretion|up-regulation of pancreatic amylase secretion|activation of pancreatic amylase secretion|up regulation of pancreatic amylase secretion Any process that activates or increases the frequency, rate or extent of pancreatic amylase secretion. GO:1902279 positive regulation of pancreatic amylase secretion by cholecystokinin signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902279 upregulation of pancreatic amylase secretion by cholecystokinin signaling pathway|CCK-mediated pancreatic amylase secretion|CCK-induced amylase release in pancreatic cell|up regulation of pancreatic amylase secretion by cholecystokinin signaling pathway|activation of pancreatic amylase secretion by cholecystokinin signaling pathway|cholecystokinin-mediated pancreatic amylase secretion|CCK-stimulated pancreatic amylase release|up-regulation of pancreatic amylase secretion by cholecystokinin signaling pathway A cholecystokinin signaling pathway that results in positive regulation of pancreatic amylase secretion. CHEBI:27691 alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27691 GO:1902276 regulation of pancreatic amylase secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902276 Any process that modulates the frequency, rate or extent of pancreatic amylase secretion. CHEBI:27692 lipid II biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27692 GO:1902277 negative regulation of pancreatic amylase secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902277 inhibition of pancreatic amylase secretion|down-regulation of pancreatic amylase secretion|downregulation of pancreatic amylase secretion|down regulation of pancreatic amylase secretion Any process that stops, prevents or reduces the frequency, rate or extent of pancreatic amylase secretion. CHEBI:27693 sitosterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27693 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902285 semaphorin-plexin signaling pathway involved in neuron protrusion guidance|semaphorin-plexin signalling pathway involved in neurite guidance|semaphorin-plexin signaling pathway involved in neuronal cell projection guidance|semaphorin-plexin signalling pathway involved in neuron process guidance|semaphorin-plexin signalling pathway involved in neuron protrusion guidance|semaphorin-plexin signaling pathway involved in neurite guidance|semaphorin-plexin signalling pathway involved in neuronal cell projection guidance|semaphorin-plexin signaling pathway involved in neuron process guidance|semaphorin-plexin signalling pathway involved in neuron projection guidance Any semaphorin-plexin signaling pathway that is involved in neuron projection guidance. GO:1902286 semaphorin-plexin signaling pathway involved in dendrite guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902286 semaphorin-plexin signalling pathway involved in dendritic guidance|semaphorin-plexin signalling pathway involved in dendrite guidance|semaphorin-plexin signaling pathway involved in dendritic guidance Any semaphorin-plexin signaling pathway that is involved in dendrite guidance. CHEBI:37018 pyrimidine ribonucleoside 3'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37018 GO:1902283 negative regulation of primary amine oxidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902283 downregulation of primary-amine:oxygen oxidoreductase (deaminating) activity|inhibition of amine oxidase (copper-containing) activity|down regulation of primary-amine:oxygen oxidoreductase (deaminating) activity|inhibition of primary-amine:oxygen oxidoreductase (deaminating) activity|down-regulation of primary amine oxidase activity|down-regulation of amine oxidase (copper-containing) activity|negative regulation of amine oxidase (copper-containing) activity|downregulation of primary amine oxidase activity|down regulation of primary amine oxidase activity|inhibition of primary amine oxidase activity|downregulation of amine oxidase (copper-containing) activity|negative regulation of primary-amine:oxygen oxidoreductase (deaminating) activity|down-regulation of primary-amine:oxygen oxidoreductase (deaminating) activity|down regulation of amine oxidase (copper-containing) activity Any process that stops, prevents or reduces the frequency, rate or extent of primary amine oxidase activity. CHEBI:37015 ribonucleoside 5'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37015 GO:1902284 neuron projection extension involved in neuron projection guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902284 neuron projection extension involved in neuron process guidance|neuronal cell projection extension involved in neurite guidance|neurite extension involved in neuron protrusion guidance|neuron protrusion extension involved in neurite guidance|neuron process extension involved in neuron protrusion guidance|neuron process extension involved in neuronal cell projection guidance|neuron projection extension involved in neuronal cell projection guidance|neuronal cell projection extension involved in neuron protrusion guidance|neuron protrusion extension involved in neuron protrusion guidance|neuron protrusion extension involved in neuron process guidance|neuron projection extension involved in neurite guidance|neurite extension involved in neuron process guidance|neurite extension involved in neuron projection guidance|neuronal cell projection extension involved in neuron process guidance|neuron process extension involved in neuron projection guidance|neuron process extension involved in neurite guidance|neuron protrusion extension involved in neuronal cell projection guidance|neurite extension involved in neuronal cell projection guidance|neuronal cell projection extension involved in neuronal cell projection guidance|neuron process extension involved in neuron process guidance|neurite extension involved in neurite guidance|neuronal cell projection extension involved in neuron projection guidance|neuron projection extension involved in neuron protrusion guidance|neuron protrusion extension involved in neuron projection guidance Any neuron projection extension that is involved in neuron projection guidance. CHEBI:37016 2'-deoxyribonucleoside 5'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37016 GO:1902281 negative regulation of RNA helicase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902281 negative regulation of ATP-dependent RNA helicase activity|down regulation of ATP-dependent RNA helicase activity|downregulation of ATP-dependent RNA helicase activity|down-regulation of ATP-dependent RNA helicase activity|inhibition of ATP-dependent RNA helicase activity Any process that stops, prevents or reduces the frequency, rate or extent of ATP-dependent RNA helicase activity. GO:1990817 RNA adenylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990817 Catalysis of the template-independent extension of the 3'- end of an RNA strand by addition of one adenosine molecule at a time. Cannot initiate a chain 'de novo'. The primer, depending on the source of the enzyme, may be an RNA, or oligo(A) bearing a 3'-OH terminal group. GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1902282 voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a ventricular cardiomyocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. GO:1990818 L-arginine transmembrane export from vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990818 The directed movement of L-arginine out of the vacuole, across the vacuolar membrane. GO:1990819 actin fusion focus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990819 A focus at the mating projection tip where the cell wall is degraded during conjugation with cellular fusion. Actin filaments form an aster-like structure from this location. GO:1902280 regulation of RNA helicase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902280 regulation of ATP-dependent RNA helicase activity Any process that modulates the frequency, rate or extent of ATP-dependent RNA helicase activity. GO:1990813 meiotic centromeric cohesion protection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990813 protection of centromeric cohesion during meiotic anaphase I The process in which the association between sister chromatids of a replicated chromosome centromeric region is maintained during homologous chromosome segregation after cohesin is cleaved by separase along the arm regions. GO:0001518 voltage-gated sodium channel complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001518 NIF_Subcellular:sao785001660 voltage-sensitive sodium channel complex|voltage-dependent sodium channel complex|voltage gated sodium channel complex A sodium channel in a cell membrane whose opening is governed by the membrane potential. CHEBI:13086 L-aspartate 4-semialdehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_13086 GO:1990814 DNA/DNA annealing activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990814 DNA reannealing activity A nucleic acid binding activity that brings together complementary sequences of ssDNA so that they pair by hydrogen bonds to form a double-stranded DNA. CHEBI:52651 leptomycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52651 GO:0001519 peptide amidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001519 The posttranslational conversion of C-terminal glycine-extended peptides to C-terminal alpha-amidated peptides. Occurs to over half of all peptide hormones to give bioactive peptides. This is a two step process catalyzed by a peptidyl-glycine alpha-hydroxylating monooxygenase and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase. In some organisms, this process is catalyzed by two separate enzymes, whereas in higher organisms, one polypeptide catalyzes both reactions. CHEBI:37010 ribonucleoside 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37010 GO:1990815 obsolete regulation of protein localization to cell division site after cytokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990815 OBSOLETE. Any process that modulates the frequency, rate or extent of protein localization to cell division site involved in cell separation after cytokinesis. GO:1990816 vacuole-mitochondrion membrane contact site biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990816 vacuole and mitochondria patch|vCLAMP A zone of apposition between the vacuolar membrane and the mitochondrial outer membrane, important for transfer of lipids between the two organelles. GO:0001514 selenocysteine incorporation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001514 RESID:AA0022 The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. Selenocysteine is synthesized from serine before its incorporation; it is not a posttranslational modification of peptidyl-cysteine. CHEBI:37013 ribonucleoside 3'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37013 CHEBI:37014 2'-deoxyribonucleoside 3'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37014 GO:1990810 microtubule anchoring at mitotic spindle pole body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990810 Any process in which a microtubule is maintained in a specific location in a cell by attachment to a mitotic spindle pole body. Microtubules attach to spindle pole bodies at the minus end. GO:0001515 opioid peptide activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0001515 Naturally occurring peptide that is an opioid (any non-alkaloid having an opiate-like effect that can be reversed by naloxone or other recognized morphine antagonist). These include Leu- and Met-enkephalin, dynorphin and neoendorphin, alpha, beta, gamma and delta endorphins formed from beta-lipotropin, various pronase-resistant peptides such as beta casamorphin, and other peptides whose opiate-like action seems to be indirect. GO:1990811 MWP complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990811 Msd1-Wdr8-Pkl1 complex A protein ternary complex that anchors microtubule minus ends to mitotic spindle pole bodies. The founding complex contains a microtubule anchoring protein (Msd1 in fission yeast), A WD-repeat Wdr8 family protein and and a minus end-directed kinesin. CHEBI:37011 4-oxoproline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37011 GO:0001516 prostaglandin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001516 prostaglandin anabolism|prostaglandin synthesis|prostaglandin formation|prostaglandin biosynthesis The chemical reactions and pathways resulting in the formation of prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring. GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0001517 Reactome:R-HSA-6786012|Reactome:R-HSA-2046222|Reactome:R-HSA-3656269 N-acetylglucosamine 6-O-sulphotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-acetyl-D-glucosamine = adenosine 3',5'-bisphosphate + N-acetyl-D-glucosamine 6-sulfate. GO:1990812 growth cone filopodium biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990812 A thin, stiff protrusion extended by the leading edge of an axonal or dendritic growth cone. CHEBI:37012 L-3-oxoalanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37012 GO:0001521 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001521 GO:0001522 pseudouridine synthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001522 Wikipedia:Pseudouridylation|Wikipedia:Pseudouridine pseudouridylation The intramolecular conversion of uridine to pseudouridine within an RNA molecule. This posttranscriptional base modification occurs in tRNA, rRNA, and snRNAs. CHEBI:52648 N(beta)-acyl-L-2,3-diaminopropionic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52648 GO:0001523 retinoid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001523 retinoid metabolism The chemical reactions and pathways involving retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity. CHEBI:52649 1-O-oleoyl-sn-glycero-3-phosphoserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52649 GO:0001524 obsolete globin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001524 globin OBSOLETE. The colorless and basic protein moiety of hemoglobin and myoglobins. GO:0001520 outer dense fiber biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001520 outer dense fibre A supramolecular fiber found in the flagella of mammalian sperm that surrounds the nine microtubule doublets. These dense fibers are stiff and noncontractile. In human, they consist of about 10 major and at least 15 minor proteins, where all major proteins are ODF1, ODF2 or ODF2-related proteins. CHEBI:52646 leptomycin B biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52646 GO:1902289 negative regulation of defense response to oomycetes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902289 down-regulation of defense response to oomycetes|inhibition of defense response to oomycetes|down regulation of defense response to oomycetes|downregulation of defense response to oomycetes Any process that stops, prevents or reduces the frequency, rate or extent of defense response to oomycetes. GO:1902287 semaphorin-plexin signaling pathway involved in axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902287 semaphorin-plexin signalling pathway involved in axon pathfinding|semaphorin-plexin signalling pathway involved in axon guidance|semaphorin-plexin signaling pathway involved in axon growth cone guidance|semaphorin-plexin signalling pathway involved in axon chemotaxis|semaphorin-plexin signaling pathway involved in axon pathfinding|semaphorin-plexin signalling pathway involved in axon growth cone guidance|semaphorin-plexin signaling pathway involved in axon chemotaxis Any semaphorin-plexin signaling pathway that is involved in axon guidance. GO:1902288 regulation of defense response to oomycetes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902288 Any process that modulates the frequency, rate or extent of defense response to oomycetes. GO:1902296 DNA strand elongation involved in cell cycle DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902296 DNA replication elongation involved in cell cycle DNA replication|DNA strand elongation during DNA replication involved in cell cycle DNA replication Any DNA strand elongation that is involved in cell cycle DNA replication. GO:1902297 cell cycle DNA replication DNA unwinding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902297 DNA unwinding during replication involved in cell cycle DNA replication|DNA unwinding factor involved in cell cycle DNA replication|DNA unwinding involved in cell cycle DNA replication Any DNA unwinding that is involved in cell cycle DNA replication. GO:1902294 cell cycle DNA replication termination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902294 DNA replication termination involved in cell cycle DNA replication Any DNA replication termination that is involved in cell cycle DNA replication. GO:1902295 synthesis of RNA primer involved in cell cycle DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902295 DNA replication, synthesis of RNA primer involved in cell cycle DNA replication|replication priming involved in cell cycle DNA replication Any DNA replication, synthesis of RNA primer that is involved in cell cycle DNA replication. GO:1902292 cell cycle DNA replication initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902292 DNA endoreduplication initiation involved in cell cycle DNA replication|DNA re-replication initiation involved in cell cycle DNA replication|DNA replication initiation involved in cell cycle DNA replication|DNA-dependent DNA replication initiation involved in cell cycle DNA replication Any DNA replication initiation that is involved in cell cycle DNA replication. GO:1990828 hepatocyte dedifferentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990828 The process in which a hepatocyte (specialized epithelial cell of the liver) loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors. GO:1902293 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902293 GO:1990829 C-rich single-stranded DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990829 C-rich ssDNA binding Interacting selectively and non-covalently with C-rich, single-stranded DNA. GO:1902290 positive regulation of defense response to oomycetes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902290 up regulation of defense response to oomycetes|activation of defense response to oomycetes|up-regulation of defense response to oomycetes|upregulation of defense response to oomycetes Any process that activates or increases the frequency, rate or extent of defense response to oomycetes. GO:1902291 cell cycle DNA replication DNA ligation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902291 DNA ligation involved in cell cycle DNA replication Any DNA ligation that is involved in cell cycle DNA replication. GO:1990824 obsolete magnesium-dependent protein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990824 OBSOLETE. A protein complex that depends on magnesium in order for one or more of its components to remain a part of the complex. CHEBI:37020 purine ribonucleoside 3'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37020 GO:0001529 obsolete elastin biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001529 elastin OBSOLETE. (Was not defined before being made obsolete). GO:1990825 sequence-specific mRNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990825 Interacting selectively and non-covalently with messenger RNA (mRNA) of a specific nucleotide composition or a specific sequence motif. CHEBI:37021 purine ribonucleoside 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37021 CHEBI:52640 N-acylethanolamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52640 GO:1990826 nucleoplasmic periphery of the nuclear pore complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990826 Nucleoplasm situated in close proximity and peripheral to a nuclear pore complex. CHEBI:52641 polyphosphoric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52641 GO:1990827 deaminase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990827 Interacting selectively and non-covalently with an enzyme that catalyzes the removal of an amino group from a substrate, producing ammonia (NH3). GO:1990820 response to mitotic DNA integrity checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990820 response to signal involved in mitotic DNA integrity checkpoint A process that occurs in response to signals generated as a result of mitotic DNA integrity checkpoint signaling. GO:0001525 angiogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001525 Wikipedia:Angiogenesis blood vessel formation from pre-existing blood vessels Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels. CHEBI:37024 2-aminoadipic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37024 GO:1990821 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990821 GO:0001526 obsolete proteoglycan sulfate transfer biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001526 proteoglycan sulphate transfer|proteoglycan sulfate transfer OBSOLETE. Transfer of sulfate to a proteoglycan (a glycoprotein whose carbohydrate units are glycosaminoglycans) using 3'-phosphoadenyl sulfate. CHEBI:37025 D-2-aminoadipic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37025 CHEBI:37022 amino-acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37022 GO:1990822 basic amino acid transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990822 The directed movement of basic amino acids from one side of a membrane to the other. GO:0001527 microfibril biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001527 fibrillin|extended fibrils Extracellular matrix components occurring independently or along with elastin. Thought to have force-bearing functions in tendon. In addition to fibrillins, microfibrils may contain other associated proteins. GO:1990823 response to leukemia inhibitory factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990823 response to LIF|response to cholinergic differentiation factor|response to CDF Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus. GO:0001528 obsolete elastin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001528 elastin OBSOLETE. A major structural protein of mammalian connective tissues; composed of one third glycine, and also rich in proline, alanine, and valine. Chains are cross-linked together via lysine residues. CHEBI:37023 L-2-aminoadipic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37023 CHEBI:52639 N-acylsphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52639 CHEBI:27676 L-histidinal biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27676 CHEBI:27678 dTDP-3-dehydro-6-deoxy-alpha-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27678 CHEBI:27675 chlorohydroquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27675 GO:1902298 cell cycle DNA replication maintenance of fidelity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902298 maintenance of fidelity during DNA-dependent DNA replication involved in cell cycle DNA replication|maintenance of fidelity involved in cell cycle DNA replication Any maintenance of fidelity that is involved in cell cycle DNA replication. CHEBI:27670 1,2-bis(3,4-dimethoxyphenyl)propane-1,3-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27670 GO:1902299 pre-replicative complex assembly involved in cell cycle DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902299 pre-replication complex assembly involved in cell cycle DNA replication|pre-RC assembly involved in cell cycle DNA replication Any pre-replicative complex assembly that is involved in cell cycle DNA replication. CHEBI:13022 keto-D-sorbose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_13022 CHEBI:52625 inorganic hydroxy compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52625 GO:0001501 skeletal system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001501 skeletal development The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton). GO:0001502 cartilage condensation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001502 The condensation of mesenchymal cells that have been committed to differentiate into chondrocytes. CHEBI:27689 decanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27689 CHEBI:27684 phenylmercury acetate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27684 CHEBI:52629 EC 3.1.26.13 (retroviral ribonuclease H) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52629 CHEBI:27680 galactomannan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27680 CHEBI:27681 (S)-2-acetyl-2-hydroxybutanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27681 CHEBI:37007 nicotinamide dinucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37007 CHEBI:37005 (3S,5R)-1-pyrroline-3-hydroxy-5-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37005 CHEBI:37008 nicotinic acid mononucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37008 CHEBI:37009 ribonucleoside 3'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37009 GO:0001507 acetylcholine catabolic process in synaptic cleft biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001507 acetylcholine breakdown in synaptic cleft|acetylcholine degradation in synaptic cleft The chemical reactions and pathways resulting in the breakdown of acetylcholine that occurs in the synaptic cleft during synaptic transmission. GO:0001508 action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001508 A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities. GO:0001509 obsolete legumain activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001509 legumain activity|hemoglobinase activity|asparaginyl endopeptidase activity|bean endopeptidase activity|proteinase B|phaseolin activity|PRSC1 gene product (Homo sapiens)|vicilin peptidohydrolase activity|citvac OBSOLETE. Catalysis of the hydrolysis of proteins and small-molecule substrates at Asn-Xaa bonds. GO:0001503 ossification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001503 Wikipedia:Ossification bone formation|osteogenesis|bone biosynthesis The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance. GO:0001504 neurotransmitter uptake biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0001504 neurotransmitter import into neuron|neurotransmitter import into glial cell|neurotransmitter recycling|neurotransmitter import The directed movement of neurotransmitters into neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters. GO:0001505 regulation of neurotransmitter levels biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001505 Any process that modulates levels of neurotransmitter. GO:0001506 obsolete neurotransmitter biosynthetic process and storage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001506 neurotransmitter biosynthetic process and storage|neurotransmitter anabolism and storage|neurotransmitter synthesis and storage|neurotransmitter formation and storage OBSOLETE. The chemical reactions and pathways resulting in the formation of neurotransmitters and the storage of the synthesized molecules. CHEBI:52615 4-formylzymosterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52615 CHEBI:27659 2-oxo aldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27659 CHEBI:52617 7,8-dihydro-8-oxoguanine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52617 CHEBI:27656 camptothecin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27656 CHEBI:27657 N-succinyl-L-glutamic 5-semialdehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27657 CHEBI:27652 2',3'-cyclic CMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27652 CHEBI:52618 2-hydroxy carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52618 CHEBI:13043 3-amino-L-alaninate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_13043 CHEBI:52603 1-acyl-sn-glycero-3-phosphoserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52603 CHEBI:27666 actinomycin D biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27666 CHEBI:27667 beta-D-galactose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27667 CHEBI:52602 ganglioside GP1c biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52602 CHEBI:27668 (S)-3-hydroxylauroyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27668 CHEBI:27660 pyrrole-2-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27660 GO:0050422 strictosidine beta-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050422 RHEA:12917|KEGG_REACTION:R03820|MetaCyc:STRICTOSIDINE-BETA-GLUCOSIDASE-RXN|EC:3.2.1.105 strictosidine b-glucosidase activity|strictosidine beta-D-glucohydrolase activity Catalysis of the reaction: 3alpha(S)-strictosidine + H(2)O = D-glucose + strictosidine aglycone. GO:0050423 thiamine oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050423 EC:1.1.3.23|MetaCyc:THIAMIN-OXIDASE-RXN|RHEA:21280 thiamine:oxygen 5-oxidoreductase activity|thiamin oxidase activity|thiamine dehydrogenase activity|thiamin:oxygen 5-oxidoreductase activity|thiamin dehydrogenase activity Catalysis of the reaction: thiamine + 2 O2 = thiamine acetic acid + 2 H2O2. GO:0050420 maltose synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050420 MetaCyc:MALTOSE-SYNTHASE-RXN|RHEA:22320|EC:2.4.1.139 alpha-D-glucose-1-phosphate:alpha-D-glucose-1-phosphate 4-alpha-D-glucosyltransferase (dephosphorylating) Catalysis of the reaction: 2 alpha-D-glucose 1-phosphate = maltose + 2 phosphate. GO:0050421 nitrite reductase (NO-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050421 MetaCyc:NITRITE-REDUCTASE-CYTOCHROME-RXN|RHEA:15233|EC:1.7.2.1 nitric-oxide:ferricytochrome-c oxidoreductase activity|nitrite reductase (cytochrome; NO-forming) activity|[nitrite reductase (cytochrome)]|cd-cytochrome nitrite reductase activity|cytochrome cd activity|NO-forming nitrite reductase (cytochrome) activity|Pseudomonas cytochrome oxidase activity|cytochrome cd1 activity|cytochrome c-551:O(2), NO(2)(+) oxidoreductase activity|NO-forming nitrite reductase activity|methyl viologen-nitrite reductase activity|cytochrome c-551:O2, NO2+ oxidoreductase activity Catalysis of the reaction: nitric oxide + H2O + ferricytochrome c = nitrite + ferrocytochrome c + 2 H+. GO:0050426 obsolete peptidyl-glycinamidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050426 peptidyl-glycinamidase activity|peptidyl carboxyamidase activity|peptidyl carboxy-amidase activity|carboxyamidase activity|peptidyl amino acid amide hydrolase activity|carboxamidopeptidase activity OBSOLETE. Catalysis of the reaction: H2O + peptidyl-glycinamide = glycinamide + peptide. Cleavage of C-terminal glycinamide from a polypeptide. GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050427 MetaCyc:PWY-5340 adenosine 3'-phosphate 5'-phosphosulfate metabolism|PAPS metabolic process|PAPS metabolism|adenosine 3'-phosphate 5'-phosphosulfate metabolic process|3'-phosphoadenylyl-sulfate metabolism|phosphoadenosine phosphosulfate metabolic process|3'-phosphoadenosine 5'-phosphosulphate metabolism|3'-phosphoadenosine 5'-phosphosulfate metabolism|3'-phosphoadenosine 5'-phosphosulphate metabolic process|phosphoadenosine phosphosulfate metabolism|3'-phosphoadenylyl-sulfate metabolic process The chemical reactions and pathways involving 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems. GO:0050424 obsolete alanine carboxypeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050424 alanine carboxypeptidase activity|N-benzoyl-L-alanine-amidohydrolase activity OBSOLETE. Catalysis of the reaction: H2O + peptidyl-L-alanine = L-alanine + peptide. The release of a C-terminal alanine from a peptide or a variety of pteroyl or acyl groups. GO:0050425 obsolete carboxypeptidase B activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050425 carboxypeptidase B activity|tissue carboxypeptidase B|pancreatic carboxypeptidase B|protaminase activity|peptidyl-L-lysine [L-arginine]hydrolase activity OBSOLETE. Catalysis of the reaction: H2O + peptidyl-L-lysine (or L-arginine) = L-lysine (or L-arginine) + peptide. Preferential release of a C-terminal lysine or arginine amino acid. GO:0050428 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050428 3'-phosphoadenosine 5'-phosphosulfate anabolism|3'-phosphoadenosine 5'-phosphosulfate synthesis|PAPS biosynthesis|PAPS biosynthetic process|3'-phosphoadenosine 5'-phosphosulfate formation|3'-phosphoadenylyl-sulfate biosynthetic process|3'-phosphoadenylyl-sulfate biosynthesis|3'-phosphoadenosine 5'-phosphosulphate biosynthesis|3'-phosphoadenosine 5'-phosphosulphate biosynthetic process|3'-phosphoadenosine 5'-phosphosulfate biosynthesis|phosphoadenosine phosphosulfate biosynthesis|phosphoadenosine phosphosulfate biosynthetic process|adenosine 3'-phosphate 5'-phosphosulfate biosynthetic process|adenosine 3'-phosphate 5'-phosphosulfate biosynthesis The chemical reactions and pathways resulting in the formation of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems. GO:0050429 calcium-dependent phospholipase C activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050429 Catalysis of the reaction: a phosphatidylcholine + H2O = 1,2-diacylglycerol + choline phosphate. This reaction requires Ca2+. CL:0000362 epidermal cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000362 cell of epidermis|epithelial cell of skin An epithelial cell of the integument (the outer layer of an organism). CL:0000365 animal zygote biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000365 zygote Diploid cell produced by the fusion of sperm cell nucleus and egg cell. GO:0050433 regulation of catecholamine secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050433 Any process that modulates the frequency, rate or extent of the regulated release of catecholamines. GO:0050434 positive regulation of viral transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050434 up regulation of viral transcription|activation of viral transcription|stimulation of viral transcription|up-regulation of viral transcription|upregulation of viral transcription Any process that activates or increases the frequency, rate or extent of viral transcription. GO:0050431 transforming growth factor beta binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050431 TGFbeta binding|transforming growth factor beta ligand binding to type II receptor|transforming growth factor beta ligand binding to type I receptor|TGF-beta binding Interacting selectively and non-covalently with TGF-beta, transforming growth factor beta, a multifunctional peptide that controls proliferation, differentiation and other functions in many cell types. GO:0050432 catecholamine secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050432 The regulated release of catecholamines by a cell. The catecholamines are a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. GO:0050437 (-)-endo-fenchol synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050437 MetaCyc:4.2.3.10-RXN|RHEA:20565|KEGG_REACTION:R02004|EC:4.2.3.10 (-)-endo-fenchol cyclase activity|geranyl-diphosphate diphosphate-lyase [cyclizing, (-)-endo-fenchol-forming]|geranyl pyrophosphate:(-)-endo-fenchol cyclase activity Catalysis of the reaction: geranyl diphosphate + H(2)O = (-)-endo-fenchol + diphosphate. GO:0050438 2-ethylmalate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050438 EC:2.3.3.6|MetaCyc:2-ETHYLMALATE-SYNTHASE-RXN|RHEA:23040|KEGG_REACTION:R00998 propylmalate synthase activity|(R)-2-ethylmalate 2-oxobutanoyl-lyase (CoA-acetylating) activity|propylmalic synthase activity|acetyl-CoA:2-oxobutanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)|2-ethylmalate-3-hydroxybutanedioate synthase activity Catalysis of the reaction: 2-oxobutanate + acetyl-CoA + H(2)O = (R)-2-ethylmalate + CoA + H(+). GO:0050435 amyloid-beta metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050435 beta-amyloid metabolism|amyloid-beta metabolism|beta-amyloid metabolic process The chemical reactions and pathways involving amyloid-beta, a glycoprotein associated with Alzheimer's disease, and its precursor, amyloid precursor protein (APP). GO:0050436 microfibril binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050436 Interacting selectively and non-covalently with a microfibril, any small fibril occurring in biological material. GO:0050439 2-hydroxy-3-oxoadipate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050439 KEGG_REACTION:R00474|RHEA:14341|EC:2.2.1.5|MetaCyc:2-HYDROXY-3-OXOADIPATE-SYNTHASE-RXN oxoglutarate:glyoxylate carboligase activity|2-hydroxy-3-oxoadipate glyoxylate-lyase (carboxylating) activity|2-hydroxy-3-oxoadipate synthetase activity|2-oxoglutarate:glyoxylate succinaldehydetransferase (decarboxylating)|alpha-ketoglutaric-glyoxylic carboligase activity|oxoglutarate: glyoxylate carboligase activity Catalysis of the reaction: 2-oxoglutarate + glyoxylate + H(+) = 2-hydroxy-3-oxoadipate + CO(2). CL:0000373 histoblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000373 GO:0050430 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050430 GO:0050444 obsolete aquacobalamin reductase (NADPH) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050444 RHEA:20752|MetaCyc:AQUACOBALAMIN-REDUCTASE-NADPH-RXN|EC:1.16.1.5 cob(II)alamin:NADP+ oxidoreductase activity|NADPH-linked aquacobalamin reductase activity|aquacobalamin (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|aquacobalamin (reduced nicotinamide adenine dinucleotide phosphate) activity|NADPH:aquacob(III)alamin oxidoreductase activity|NADPH2:aquacob(III)alamin oxidoreductase activity OBSOLETE. Catalysis of the reaction: 2 cob(II)alamin + NADP+ = 2 aquacob(III)alamin + NADPH + H+. GO:0050445 asparagusate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050445 EC:1.8.1.11|KEGG_REACTION:R03761|RHEA:14881|MetaCyc:ASPARAGUSATE-REDUCTASE-NADH-RXN asparagusate reductase (NADH2)|asparagusic dehydrogenase activity|3-mercapto-2-mercaptomethylpropanoate:NAD+ oxidoreductase activity|asparagusate reductase (NADH) activity|NADH:asparagusate oxidoreductase activity|asparagusate dehydrogenase activity|NADH2:asparagusate oxidoreductase activity Catalysis of the reaction: 3-mercapto-2-mercaptomethylpropanoate + NAD(+) = asparagusate + H(+) + NADH. GO:0050442 3-propylmalate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050442 EC:2.3.3.12|RHEA:14457|MetaCyc:3-PROPYLMALATE-SYNTHASE-RXN|KEGG_REACTION:R03040 3-(n-propyl)-malate synthase activity|3-propylmalate glyoxylate-lyase (CoA-pentanoylating) activity|N-propylmalate synthase activity|pentanoyl-CoA:glyoxylate C-pentanoyltransferase (thioester-hydrolysing, 1-carboxybutyl-forming)|beta-n-propylmalate synthase activity Catalysis of the reaction: glyoxylate + H(2)O + pentanoyl-CoA = 3-propylmalate + CoA + H(+). GO:0050443 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050443 GO:0050448 beta-cyclopiazonate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050448 EC:1.21.99.1|RHEA:14526|KEGG_REACTION:R04080|MetaCyc:BETA-CYCLOPIAZONATE-DEHYDROGENASE-RXN beta-cyclopiazonic oxidocyclase activity|beta-cyclopiazonate:acceptor oxidoreductase (cyclizing)|beta-cyclopiazonate oxidocyclase activity|beta-cyclopiazonate:(acceptor) oxidoreductase (cyclizing)|b-cyclopiazonate dehydrogenase activity Catalysis of the reaction: beta-cyclopiazonate + A = alpha-cyclopiazonate + AH(2). GO:0050449 casbene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050449 RHEA:14901|EC:4.2.3.8|KEGG_REACTION:R02064|MetaCyc:CASBENE-SYNTHASE-RXN casbene synthetase activity|geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, casbene-forming)|geranylgeranyl-diphosphate diphosphate-lyase (cyclizing) Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = casbene + diphosphate. GO:0050446 azobenzene reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050446 MetaCyc:AZOBENZENE-REDUCTASE-RXN|EC:1.7.1.6|RHEA:16269|UM-BBD_reactionID:r0808 NAD(P)H:1-(4'-sulfophenylazo)-2-naphthol oxidoreductase activity|azo reductase activity|NC-reductase activity|azo-dye reductase activity|New coccine (NC)-reductase activity|nicotinamide adenine dinucleotide (phosphate) azoreductase activity|dibromopropylaminophenylazobenzoic azoreductase activity|new coccine (NC)-reductase|orange I azoreductase activity|N,N-dimethyl-1,4-phenylenediamine, aniline:NADP+ oxidoreductase activity|orange II azoreductase activity|NADPH2-dependent azoreductase activity|azoreductase activity|methyl red azoreductase activity|NADPH2:4-(dimethylamino)azobenzene oxidoreductase activity|NADPH:4-(dimethylamino)azobenzene oxidoreductase activity|dimethylaminobenzene reductase activity|NADPH-dependent azoreductase activity|p-dimethylaminoazobenzene azoreductase activity|N,N-dimethyl-4-phenylazoaniline azoreductase activity|p-aminoazobenzene reductase activity Catalysis of the reaction: N,N-dimethyl-1,4-phenylenediamine + aniline + NADP+ = 4-(dimethylamino)azobenzene + NADPH + H+. GO:0050447 zeatin 9-aminocarboxyethyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050447 EC:2.5.1.50|KEGG_REACTION:R03133|RHEA:17333|MetaCyc:BETA-9-CYTOKININ-ALANINE-SYNTHASE-RXN O-acetyl-L-serine acetate-lyase (adding N(6)-substituted adenine) activity|beta-(9-cytokinin)-alanine synthase activity|lupinic acid synthase activity|lupinate synthetase activity|3-O-acetyl-L-serine:zeatin 2-amino-2-carboxyethyltransferase activity|O-acetyl-L-serine acetate-lyase (adding N6-substituted adenine)|lupinic acid synthetase activity|beta-(9-cytokinin)alanine synthase activity|O3-acetyl-L-serine:zeatin 2-amino-2-carboxyethyltransferase activity Catalysis of the reaction: O-acetyl-L-serine + zeatin = L-lupinate + acetate + H(+). CL:0000349 extraembryonic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000349 CL:0000341 pigment cell (sensu Nematoda and Protostomia) biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000341 GO:0050440 2-methylcitrate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050440 KEGG_REACTION:R00931|EC:2.3.3.5|RHEA:23780|MetaCyc:2-METHYLCITRATE-SYNTHASE-RXN propanoyl-CoA:oxaloacetate C-propanoyltransferase (thioester-hydrolysing, 1-carboxyethyl-forming)|methylcitrate synthase activity|2-methylcitrate oxaloacetate-lyase activity|methylcitrate synthetase activity|MCS activity Catalysis of the reaction: H(2)O + oxaloacetate + propanoyl-CoA = (2R,3S)-2-methylcitrate + CoA + H(+). GO:0050441 3-ethylmalate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050441 RHEA:10500|EC:2.3.3.7|MetaCyc:3-ETHYLMALATE-SYNTHASE-RXN|KEGG_REACTION:R01180 2-ethyl-3-hydroxybutanedioate synthase activity|3-ethylmalate glyoxylate-lyase (CoA-butanoylating) activity|butanoyl-CoA:glyoxylate C-butanoyltransferase (thioester-hydrolysing, 1-carboxypropyl-forming) Catalysis of the reaction: butanoyl-CoA + glyoxylate + H(2)O = 3-ethylmalate + CoA + H(+). GO:0050455 columbamine oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050455 EC:1.21.3.2|MetaCyc:COLUMBAMINE-OXIDASE-RXN|RHEA:23564|KEGG_REACTION:R00044 berberine synthase activity|columbamine:oxygen oxidoreductase (cyclizing) Catalysis of the reaction: 2 columbamine + O(2) = 2 berberine + 2 H(2)O. GO:0050456 cystine reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050456 MetaCyc:CYSTINE-REDUCTASE-NADH-RXN|RHEA:20597|KEGG_REACTION:R00892|EC:1.8.1.6 NADH:L-cystine oxidoreductase activity|NADH-dependent cystine reductase activity|cystine reductase (NADH2)|L-cysteine:NAD+ oxidoreductase|cystine reductase (NADH) activity|NADH2:L-cystine oxidoreductase Catalysis of the reaction: 2 L-cysteine + NAD(+) = L-cystine + H(+) + NADH. GO:0050453 cob(II)alamin reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050453 RHEA:17481|Reactome:R-HSA-3149560|MetaCyc:COBIIALAMIN-REDUCTASE-RXN|KEGG_REACTION:R00099|EC:1.16.1.4 vitamin B12 reduction|vitamin B12 reductase activity|vitamin B12r reductase activity|B(12r) reductase activity|NADH2:cob(II)alamin oxidoreductase activity|NADH:cob(II)alamin oxidoreductase activity|vitamin B(12r) reductase activity|cob(I)alamin:NAD+ oxidoreductase activity|B12r reductase activity Catalysis of the reaction: 2 cob(I)alamin + H(+) + NAD(+) = 2 cob(II)alamin + NADH. GO:0050454 coenzyme F420 hydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050454 MetaCyc:COENZYME-F420-HYDROGENASE-RXN|EC:1.12.98.1|KEGG_REACTION:R03025|RHEA:23760 8-hydroxy-5-deazaflavin-reducing hydrogenase activity|coenzyme F420-dependent hydrogenase activity|hydrogen:coenzyme F420 oxidoreductase activity|F420-reducing hydrogenase activity Catalysis of the reaction: coenzyme F420 + H(2) + H(+) = reduced coenzyme F420. GO:1902209 negative regulation of bacterial-type flagellum assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902209 inhibition of bacterial-type flagellum assembly|down-regulation of bacterial flagellum assembly|negative regulation of bacterial flagellum assembly|down regulation of bacterial-type flagellum assembly|downregulation of bacterial flagellum assembly|downregulation of bacterial-type flagellum assembly|down regulation of bacterial flagellum assembly|inhibition of bacterial flagellum assembly|down-regulation of bacterial-type flagellum assembly Any process that stops, prevents or reduces the frequency, rate or extent of bacterial-type flagellum assembly. GO:0050459 ethanolamine-phosphate phospho-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050459 EC:4.2.3.2|MetaCyc:ETHANOLAMINE-PHOSPHATE-PHOSPHO-LYASE-RXN|KEGG_REACTION:R00748|Reactome:R-HSA-5696415|RHEA:17889 O-phosphorylethanol-amine phospho-lyase activity|ethanolamine-phosphate phospho-lyase (deaminating)|amino alcohol O-phosphate phospholyase activity|ethanolamine-phosphate phospho-lyase (deaminating; acetaldehyde-forming)|O-phosphoethanolamine-phospholyase activity Catalysis of the reaction: H(2)O + phosphoethanolamine = acetaldehyde + NH(4)(+) + phosphate. GO:1902207 positive regulation of interleukin-2-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902207 up regulation of IL-2-mediated signaling pathway|activation of IL-2-mediated signaling pathway|positive regulation of IL-2-mediated signaling pathway|up-regulation of interleukin-2-mediated signalling pathway|upregulation of interleukin-2-mediated signaling pathway|up-regulation of IL-2-mediated signaling pathway|upregulation of interleukin-2-mediated signalling pathway|activation of interleukin-2-mediated signaling pathway|up-regulation of interleukin-2-mediated signaling pathway|upregulation of IL-2-mediated signaling pathway|up regulation of interleukin-2-mediated signalling pathway|activation of interleukin-2-mediated signalling pathway|positive regulation of interleukin-2-mediated signalling pathway|up regulation of interleukin-2-mediated signaling pathway Any process that activates or increases the frequency, rate or extent of interleukin-2-mediated signaling pathway. GO:0050457 decylcitrate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050457 EC:2.3.3.2|MetaCyc:DECYLCITRATE-SYNTHASE-RXN|KEGG_REACTION:R03735|RHEA:16605 dodecanoyl-CoA:oxaloacetate C-dodecanoyltransferase (thioester-hydrolysing, 1-carboxyundecyl-forming)|(2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate oxaloacetate-lyase (CoA- acylating) activity|2-decylcitrate synthase activity|(2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate oxaloacetate-lyase (CoA-acylating) Catalysis of the reaction: H(2)O + lauroyl-CoA + oxaloacetate = (2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate + CoA + H(+). GO:1902208 regulation of bacterial-type flagellum assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902208 regulation of bacterial flagellum assembly Any process that modulates the frequency, rate or extent of bacterial-type flagellum assembly. GO:0050458 decylhomocitrate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050458 EC:2.3.3.4|MetaCyc:DECYLHOMOCITRATE-SYNTHASE-RXN|KEGG_REACTION:R03859|RHEA:10364 3-hydroxytetradecane-1,3,4-tricarboxylate 2-oxoglutarate-lyase (CoA-acylating)|3-hydroxytetradecane-1,3,4-tricarboxylate 2-oxoglutarate-lyase (CoA- acylating) activity|dodecanoyl-CoA:2-oxoglutarate C-dodecanoyltransferase (thioester-hydrolysing, 1-carboxyundecyl-forming)|2-decylhomocitrate synthase activity Catalysis of the reaction: 2-oxoglutarate + H(2)O + lauroyl-CoA = (3S,4S)-3-hydroxytetradecane-1,3,4-tricarboxylate + CoA + H(+). GO:1902205 regulation of interleukin-2-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902205 regulation of interleukin-2-mediated signalling pathway|regulation of IL-2-mediated signaling pathway Any process that modulates the frequency, rate or extent of interleukin-2-mediated signaling pathway. GO:1902206 negative regulation of interleukin-2-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902206 down regulation of interleukin-2-mediated signaling pathway|inhibition of interleukin-2-mediated signalling pathway|down-regulation of IL-2-mediated signaling pathway|negative regulation of IL-2-mediated signaling pathway|inhibition of interleukin-2-mediated signaling pathway|inhibition of IL-2-mediated signaling pathway|down regulation of interleukin-2-mediated signalling pathway|downregulation of interleukin-2-mediated signalling pathway|down-regulation of interleukin-2-mediated signaling pathway|down regulation of IL-2-mediated signaling pathway|downregulation of IL-2-mediated signaling pathway|negative regulation of interleukin-2-mediated signalling pathway|down-regulation of interleukin-2-mediated signalling pathway|downregulation of interleukin-2-mediated signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-2-mediated signaling pathway. CL:0000359 vascular associated smooth muscle cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000359 vascular smooth muscle cell|VSMC A smooth muscle cell assocatiated with the vasculature. GO:1902203 negative regulation of hepatocyte growth factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902203 downregulation of HGF receptor signalling pathway|inhibition of Met signaling pathway|down-regulation of HGF receptor signaling pathway|negative regulation of HGF receptor signaling pathway|down regulation of hepatocyte growth factor receptor signaling pathway|down-regulation of HGF receptor signalling pathway|negative regulation of HGF receptor signalling pathway|down regulation of Met signaling pathway|downregulation of hepatocyte growth factor receptor signaling pathway|downregulation of Met signaling pathway|downregulation of HGF receptor signaling pathway|down-regulation of hepatocyte growth factor receptor signaling pathway|down regulation of HGF receptor signaling pathway|inhibition of HGF receptor signalling pathway|negative regulation of Met signaling pathway|down-regulation of Met signaling pathway|inhibition of hepatocyte growth factor receptor signaling pathway|inhibition of HGF receptor signaling pathway|down regulation of HGF receptor signalling pathway Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway. GO:1902204 positive regulation of hepatocyte growth factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902204 up-regulation of HGF receptor signaling pathway|up regulation of HGF receptor signalling pathway|upregulation of hepatocyte growth factor receptor signaling pathway|positive regulation of HGF receptor signalling pathway|activation of HGF receptor signaling pathway|upregulation of Met signaling pathway|activation of HGF receptor signalling pathway|positive regulation of HGF receptor signaling pathway|up regulation of HGF receptor signaling pathway|up regulation of hepatocyte growth factor receptor signaling pathway|up-regulation of HGF receptor signalling pathway|activation of hepatocyte growth factor receptor signaling pathway|up regulation of Met signaling pathway|positive regulation of Met signaling pathway|upregulation of HGF receptor signaling pathway|activation of Met signaling pathway|upregulation of HGF receptor signalling pathway|up-regulation of hepatocyte growth factor receptor signaling pathway|up-regulation of Met signaling pathway Any process that activates or increases the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway. GO:1902201 negative regulation of bacterial-type flagellum-dependent cell motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902201 inhibition of flagellin-based flagellar cell motility|negative regulation of bacterial-type flagellar cell motility|down regulation of flagellin-based flagellar cell motility|downregulation of flagellin-based flagellar cell motility|down-regulation of bacterial-type flagellar cell motility|negative regulation of flagellin-based flagellar cell motility|down-regulation of flagellin-based flagellar cell motility|downregulation of bacterial-type flagellar cell motility|down regulation of bacterial-type flagellar cell motility|inhibition of bacterial-type flagellar cell motility Any process that stops, prevents or reduces the frequency, rate or extent of bacterial-type flagellum-dependent cell motility. GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902202 regulation of Met signaling pathway|regulation of HGF receptor signaling pathway|regulation of HGF receptor signalling pathway Any process that modulates the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway. GO:1902200 3-methylbut-2-enoyl-CoA(4-) biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902200 3-methylbut-2-enoyl-CoA(4-) formation|3-methylbut-2-enoyl-CoA(4-) biosynthesis|3-methylbut-2-enoyl-CoA(4-) anabolism|3-methylbut-2-enoyl-CoA(4-) synthesis The chemical reactions and pathways resulting in the formation of 3-methylbut-2-enoyl-CoA(4-). CL:0000350 amnioserosal cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000350 CL:0000351 trophoblast cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000351 trophoblastic cell A cell lining the outside of the blastocyst. After binding to the endometrium, trophoblast cells develop into two distinct layers, an inner layer of mononuclear cytotrophoblast cells and an outer layer of continuous multinuclear cytoplasm, the syncytiotrophoblast cells, which form the early fetal-maternal interface. CL:0000355 multi-potent skeletal muscle stem cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000355 A multifate stem cell found in skeletal muscle than can differentiate into many different cell types, including muscle. Distinct cell type from satellite cell. CL:0000357 stratified epithelial stem cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000357 GO:0050451 CoA-disulfide reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050451 RHEA:14705|MetaCyc:COA-DISULFIDE-REDUCTASE-NADH-RXN|EC:1.8.1.14 CoA-disulfide reductase (NAD(P)H) activity|CoA-disulfide reductase (NADH2)|CoA:NAD+ oxidoreductase activity|coenzyme A disulfide reductase activity|CoA-disulfide reductase (NADH) activity|CoA:NAD(P)+ oxidoreductase activity|CoA-disulfide reductase [NAD(P)H]|CoA-disulphide reductase activity|NADH2:CoA-disulfide oxidoreductase activity|CoADR activity|NADH:CoA-disulfide oxidoreductase activity Catalysis of the reaction: 2 CoA + NAD+ = CoA-disulfide + NADH + H+. GO:0050452 CoA-glutathione reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050452 RHEA:14617|MetaCyc:COA-GLUTATHIONE-REDUCTASE-NADPH-RXN|EC:1.8.1.10 glutathione:NADP+ oxidoreductase (CoA-acylating)|NADPH:CoA-glutathione oxidoreductase activity|NADPH2:CoA-glutathione oxidoreductase activity|coenzyme A disulfide-glutathione reductase activity|NADPH-dependent coenzyme A-SS-glutathione reductase activity|CoA-glutathione reductase (NADPH) activity|coenzyme A glutathione disulfide reductase activity Catalysis of the reaction: CoA + glutathione + NADP+ = CoA-glutathione + NADPH + H+. GO:0050450 citrate (Re)-synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050450 MetaCyc:CITRATE-RE-SYNTHASE-RXN|EC:2.3.3.3 acetyl-CoA:oxaloacetate C-acetyltransferase [thioester-hydrolysing, (pro-R)-carboxymethyl-forming]|(R)-citrate synthase activity|citrate oxaloacetate-lyase [(pro-3R)-CH2COO-rightacetyl-CoA]|citrate oxaloacetate-lyase ((pro-3R)-CH(2)COO(-)->acetyl-CoA) activity|Re-citrate-synthase activity Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA, where the acetyl group is added to the re-face of oxaloacetate; acetyl-CoA provides the two carbon atoms of the pro-R carboxymethyl group. GO:0050466 obsolete oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with other acceptors biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050466 oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with other acceptors OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y and the acceptor is not disulfide or oxygen. GO:0050467 pentalenene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050467 KEGG_REACTION:R02305|EC:4.2.3.7|MetaCyc:PENTALENENE-SYNTHASE-RXN|RHEA:18081 pentalenene synthetase activity|2-trans,6-trans-farnesyldiphosphate diphosphate-lyase (cyclizing, pentalenene-forming)|2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, pentalenene-forming) Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + pentalenene. GO:0050464 nitrate reductase (NADPH) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050464 MetaCyc:NITRATE-REDUCTASE-NADPH-RXN|EC:1.7.1.3|RHEA:19061 NADPH:nitrate reductase activity|NADPH:nitrate oxidoreductase activity|nitrate reductase (NADPH2)|assimilatory NADPH-nitrate reductase activity|triphosphopyridine nucleotide-nitrate reductase activity|NADPH-nitrate reductase activity|nitrate reductase (NADPH(2)) activity|assimilatory reduced nicotinamide adenine dinucleotide phosphate-nitrate reductase activity|assimilatory nitrate reductase activity|nitrite:NADP+ oxidoreductase activity Catalysis of the reaction: nitrite + NADP+ + H2O = nitrate + NADPH + H+. GO:0050465 nitroquinoline-N-oxide reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050465 MetaCyc:1.7.1.9-RXN|EC:1.7.1.9 NAD(P)H:4-nitroquinoline-N-oxide oxidoreductase activity|4-nitroquinoline 1-oxide reductase activity|NAD(P)H2:4-nitroquinoline-N-oxide oxidoreductase activity|4-(hydroxyamino)quinoline N-oxide:NADP+ oxidoreductase activity|4NQO reductase activity Catalysis of the reaction: 4-(hydroxyamino)quinoline N-oxide + 2 NAD(P)+ + H2O = 4-nitroquinoline N-oxide + 2 NAD(P)H + 2 H+. GO:1902218 regulation of intrinsic apoptotic signaling pathway in response to osmotic stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902218 Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress. GO:0050468 reticuline oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050468 KEGG_REACTION:R03831|RHEA:19885|EC:1.21.3.3|MetaCyc:RETICULINE-OXIDASE-RXN BBE|(S)-reticuline:oxygen oxidoreductase (methylene-bridge-forming)|berberine bridge enzyme activity|berberine-bridge-forming enzyme activity|tetrahydroprotoberberine synthase activity Catalysis of the reaction: (S)-reticuline + O(2) = (S)-scoulerine + H(2)O(2) + H(+). GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902219 down regulation of intrinsic apoptotic signaling pathway in response to osmotic stress|downregulation of intrinsic apoptotic signaling pathway in response to osmotic stress|down-regulation of intrinsic apoptotic signaling pathway in response to osmotic stress|inhibition of intrinsic apoptotic signaling pathway in response to osmotic stress Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress. GO:0050469 sabinene-hydrate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050469 KEGG_REACTION:R02006|EC:4.2.3.11|RHEA:19565|MetaCyc:4.2.3.11-RXN sabinene hydrate cyclase activity|geranyl-diphosphate diphosphate-lyase (cyclizing, sabinene-hydrate-forming) Catalysis of the reaction: geranyl diphosphate + H(2)O = diphosphate + sabinene hydrate. GO:1902216 positive regulation of interleukin-4-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902216 activation of interleukin-4-mediated signaling pathway|up regulation of interleukin-4-mediated signalling pathway|positive regulation of interleukin-4-mediated signalling pathway|activation of interleukin-4-mediated signalling pathway|upregulation of IL-4-mediated signaling pathway|up regulation of interleukin-4-mediated signaling pathway|up regulation of IL-4-mediated signaling pathway|up-regulation of interleukin-4-mediated signalling pathway|positive regulation of IL-4-mediated signaling pathway|activation of IL-4-mediated signaling pathway|upregulation of interleukin-4-mediated signaling pathway|upregulation of interleukin-4-mediated signalling pathway|up-regulation of IL-4-mediated signaling pathway|up-regulation of interleukin-4-mediated signaling pathway Any process that activates or increases the frequency, rate or extent of interleukin-4-mediated signaling pathway. CL:0000325 stuff accumulating cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000325 A cell that is specialised to accumulate a particular substance(s). GO:1902217 erythrocyte apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902217 RBC apoptosis|red blood cell apoptotic process|RBC apoptotic process|erythrocyte apoptosis|red blood cell apoptosis Any apoptotic process in an erythrocyte. GO:1902214 regulation of interleukin-4-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902214 regulation of IL-4-mediated signaling pathway|regulation of interleukin-4-mediated signalling pathway Any process that modulates the frequency, rate or extent of interleukin-4-mediated signaling pathway. CL:0000327 extracellular matrix secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000327 GO:1902215 negative regulation of interleukin-4-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902215 down-regulation of interleukin-4-mediated signaling pathway|negative regulation of interleukin-4-mediated signalling pathway|down-regulation of interleukin-4-mediated signalling pathway|down regulation of IL-4-mediated signaling pathway|downregulation of IL-4-mediated signaling pathway|inhibition of interleukin-4-mediated signalling pathway|downregulation of interleukin-4-mediated signaling pathway|down regulation of interleukin-4-mediated signaling pathway|inhibition of interleukin-4-mediated signaling pathway|down-regulation of IL-4-mediated signaling pathway|negative regulation of IL-4-mediated signaling pathway|inhibition of IL-4-mediated signaling pathway|down regulation of interleukin-4-mediated signalling pathway|downregulation of interleukin-4-mediated signalling pathway Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-4-mediated signaling pathway. CL:0000328 myelin accumulating cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000328 GO:1902212 negative regulation of prolactin signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902212 down regulation of prolactin signaling pathway|inhibition of PRL signaling pathway|downregulation of prolactin signaling pathway|negative regulation of prolactin-mediated signaling pathway|down-regulation of prolactin-mediated signaling pathway|down-regulation of prolactin signaling pathway|down regulation of PRL signaling pathway|downregulation of prolactin-mediated signaling pathway|downregulation of PRL signaling pathway|down regulation of prolactin-mediated signaling pathway|inhibition of prolactin-mediated signaling pathway|inhibition of prolactin signaling pathway|down-regulation of PRL signaling pathway|negative regulation of PRL signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of prolactin signaling pathway. CL:0000329 oxygen accumulating cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000329 GO:1902213 positive regulation of prolactin signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902213 up-regulation of PRL signaling pathway|up regulation of prolactin signaling pathway|activation of prolactin signaling pathway|positive regulation of prolactin-mediated signaling pathway|up regulation of prolactin-mediated signaling pathway|upregulation of PRL signaling pathway|up-regulation of prolactin signaling pathway|upregulation of prolactin-mediated signaling pathway|up regulation of PRL signaling pathway|activation of PRL signaling pathway|positive regulation of PRL signaling pathway|upregulation of prolactin signaling pathway|up-regulation of prolactin-mediated signaling pathway|activation of prolactin-mediated signaling pathway Any process that activates or increases the frequency, rate or extent of prolactin signaling pathway. GO:1902210 positive regulation of bacterial-type flagellum assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902210 up-regulation of bacterial flagellum assembly|activation of bacterial flagellum assembly|up-regulation of bacterial-type flagellum assembly|positive regulation of bacterial flagellum assembly|upregulation of bacterial-type flagellum assembly|up regulation of bacterial flagellum assembly|up regulation of bacterial-type flagellum assembly|upregulation of bacterial flagellum assembly|activation of bacterial-type flagellum assembly Any process that activates or increases the frequency, rate or extent of bacterial-type flagellum assembly. GO:1902211 regulation of prolactin signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902211 regulation of PRL signaling pathway|regulation of prolactin-mediated signaling pathway Any process that modulates the frequency, rate or extent of prolactin signaling pathway. GO:1902220 positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902220 up-regulation of intrinsic apoptotic signaling pathway in response to osmotic stress|upregulation of intrinsic apoptotic signaling pathway in response to osmotic stress|up regulation of intrinsic apoptotic signaling pathway in response to osmotic stress|activation of intrinsic apoptotic signaling pathway in response to osmotic stress Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress. CL:0000322 pneumocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000322 pneumonocyte|alveolar epithelial cell An epithelial cell that lines the peripheral gas exchange region of the lungs of air-breathing vertebrates. CHEBI:52595 1-alkyl-2-acyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52595 GO:0050462 N-acetylneuraminate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050462 EC:2.5.1.56|MetaCyc:N-ACETYLNEURAMINATE-SYNTHASE-RXN|RHEA:19273 N-acetylneuraminic acid synthase activity|phosphoenolpyruvate:N-acetyl-D-mannosamine C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming)|N-acetylneuraminate pyruvate-lyase (pyruvate-phosphorylating) activity|(NANA)condensing enzyme activity|NeuAc synthase activity Catalysis of the reaction: phosphoenolpyruvate + N-acetyl-D-mannosamine + H2O = phosphate + N-acetylneuraminate. GO:0050463 nitrate reductase [NAD(P)H] activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050463 EC:1.7.1.2 nitrate reductase (reduced nicotinamide adenine dinucleotide (phosphate)) activity|NAD(P)H-nitrate reductase activity|nitrate reductase NAD(P)H activity|nitrite:NAD(P)+ oxidoreductase activity|assimilatory nitrate reductase activity|NAD(P)H bispecific nitrate reductase activity|NAD(P)H2:nitrate oxidoreductase activity|NAD(P)H:nitrate oxidoreductase activity|assimilatory NAD(P)H-nitrate reductase activity|nitrate reductase [NAD(P)H2] Catalysis of the reaction: nitrite + NAD(P)+ + H2O = nitrate + NAD(P)H + H+. CHEBI:52592 N-retinylidene-N-retinylphosphatidylethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52592 GO:0050460 hydroxylamine reductase (NADH) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050460 EC:1.7.1.10|RHEA:20581|MetaCyc:HYDROXYLAMINE-REDUCTASE-NADH-RXN NADH:hydroxylamine oxidoreductase activity|ammonium:NAD+ oxidoreductase activity|NADH-hydroxylamine reductase activity|hydroxylamine reductase (NADH2)|N-hydroxy amine reductase activity|ammonium dehydrogenase activity|NADH2:hydroxylamine oxidoreductase activity Catalysis of the reaction: NH3 + NAD+ + H2O = hydroxylamine + NADH + H+. GO:0050461 L-mimosine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050461 MetaCyc:RXN-7461|EC:2.5.1.52|RHEA:12693|KEGG_REACTION:R04091 3-O-acetyl-L-serine:3,4-dihydroxypyridine 1-(2-amino-2-carboxyethyl)transferase activity|O(3)-acetyl-L-serine acetate-lyase (adding 3,4-dihydroxypyridin-1-yl) activity|O3-acetyl-L-serine acetate-lyase (adding 3,4-dihydroxypyridin-1-yl)|O3-acetyl-L-serine:3,4-dihydroxypyridine 1-(2-amino-2-carboxyethyl)transferase activity Catalysis of the reaction: 3,4-dihydroxypyridine + O-acetyl-L-serine = 3-(3,4-dihydroxypyridinium-1-yl)-L-alanine + acetate. GO:0050477 acyl-lysine deacylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050477 EC:3.5.1.17|RHEA:24548|MetaCyc:ACYL-LYSINE-DEACYLASE-RXN 6-N-acyl-L-lysine amidohydrolase activity|epsilon-lysine acylase activity|N6-acyl-L-lysine amidohydrolase activity Catalysis of the reaction: H2O + N6-acyl-L-lysine = L-lysine + a carboxylate. GO:0050478 obsolete anthranilate 3-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050478 anthranilate 3-hydroxylase activity|anthranilate,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|anthranilic acid hydroxylase activity OBSOLETE. Catalysis of the reaction: 5,6,7,8-tetrahydrobiopterin + anthranilate + O(2) = 3-hydroxyanthranilate + 7,8-dihydrobiopterin + H(2)O. GO:0050475 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050475 GO:0050476 acetylenedicarboxylate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050476 MetaCyc:4.1.1.78-RXN|EC:4.1.1.78|RHEA:17733 acetylenedicarboxylate hydratase activity|acetylenedicarboxylate carboxy-lyase (pyruvate-forming)|acetylenedicarboxylate hydrase activity|acetylenedicarboxylate carboxy-lyase activity Catalysis of the reaction: H2O + acetylenedicarboxylate = CO2 + pyruvate. GO:0050479 glyceryl-ether monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050479 EC:1.14.16.5|MetaCyc:GLYCERYL-ETHER-MONOOXYGENASE-RXN|Reactome:R-HSA-5696119|RHEA:36255 alkylglycerol monooxygenase activity|glyceryl etherase activity|O-alkylglycerol monooxygenase activity|1-alkyl-sn-glycerol,tetrahydrobiopterin:oxygen oxidoreductase activity|glyceryl ether oxygenase activity|glyceryl-ether cleaving enzyme activity Catalysis of the reaction: 1-alkyl-sn-glycerol + O2 + (tetrahydrobiopterin/tetrahydropteridine) = 1-hydroxyalkyl-sn-glycerol + H2O + (dihydrobiopterin/dihydropteridine). GO:1902229 regulation of intrinsic apoptotic signaling pathway in response to DNA damage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902229 regulation of DNA damage response, signal transduction resulting in induction of apoptosis Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage. GO:1902227 negative regulation of macrophage colony-stimulating factor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902227 down-regulation of M-CSF signaling pathway|negative regulation of M-CSF signaling pathway|inhibition of macrophage colony-stimulating factor signalling pathway|inhibition of M-CSF signaling pathway|down regulation of macrophage colony-stimulating factor signalling pathway|down-regulation of macrophage colony-stimulating factor signaling pathway|downregulation of macrophage colony-stimulating factor signalling pathway|down regulation of M-CSF signaling pathway|downregulation of M-CSF signaling pathway|downregulation of macrophage colony-stimulating factor signaling pathway|down-regulation of macrophage colony-stimulating factor signalling pathway|negative regulation of macrophage colony-stimulating factor signalling pathway|down regulation of macrophage colony-stimulating factor signaling pathway|inhibition of macrophage colony-stimulating factor signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of macrophage colony-stimulating factor signaling pathway. GO:1902228 positive regulation of macrophage colony-stimulating factor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902228 upregulation of macrophage colony-stimulating factor signaling pathway|up-regulation of macrophage colony-stimulating factor signalling pathway|up-regulation of M-CSF signaling pathway|up-regulation of macrophage colony-stimulating factor signaling pathway|activation of macrophage colony-stimulating factor signaling pathway|upregulation of macrophage colony-stimulating factor signalling pathway|upregulation of M-CSF signaling pathway|up regulation of macrophage colony-stimulating factor signalling pathway|up regulation of macrophage colony-stimulating factor signaling pathway|positive regulation of macrophage colony-stimulating factor signalling pathway|activation of macrophage colony-stimulating factor signalling pathway|up regulation of M-CSF signaling pathway|positive regulation of M-CSF signaling pathway|activation of M-CSF signaling pathway Any process that activates or increases the frequency, rate or extent of macrophage colony-stimulating factor signaling pathway. GO:1902225 negative regulation of acrosome reaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902225 down-regulation of acrosome reaction|inhibition of acrosome reaction|down regulation of acrosome reaction|downregulation of acrosome reaction Any process that stops, prevents or reduces the frequency, rate or extent of acrosome reaction. CL:0000338 neuroblast (sensu Nematoda and Protostomia) biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000338 neuroblast CL:0000339 glioblast (sensu Vertebrata) biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000339 spongioblast An early neural cell developing from the early ependymal cell of the neural tube. GO:1902226 regulation of macrophage colony-stimulating factor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902226 regulation of macrophage colony-stimulating factor signalling pathway|regulation of M-CSF signaling pathway Any process that modulates the frequency, rate or extent of macrophage colony-stimulating factor signaling pathway. GO:1902223 erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902223 erythrose 4-phosphate/phosphoenolpyruvate family amino acid formation|erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthesis|erythrose 4-phosphate/phosphoenolpyruvate family amino acid anabolism|erythrose 4-phosphate/phosphoenolpyruvate family amino acid synthesis The chemical reactions and pathways resulting in the formation of erythrose 4-phosphate/phosphoenolpyruvate family amino acid. GO:1902224 ketone body metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902224 ketone body metabolism The chemical reactions and pathways involving ketone body. GO:1902221 erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902221 erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolism The chemical reactions and pathways involving erythrose 4-phosphate/phosphoenolpyruvate family amino acid. GO:1902222 erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902222 erythrose 4-phosphate/phosphoenolpyruvate family amino acid degradation|erythrose 4-phosphate/phosphoenolpyruvate family amino acid breakdown|erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolism The chemical reactions and pathways resulting in the breakdown of erythrose 4-phosphate/phosphoenolpyruvate family amino acid. GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902230 down-regulation of intrinsic apoptotic signaling pathway in response to DNA damage|inhibition of DNA damage response, signal transduction resulting in induction of apoptosis|inhibition of intrinsic apoptotic signaling pathway in response to DNA damage|down-regulation of DNA damage response, signal transduction resulting in induction of apoptosis|negative regulation of DNA damage response, signal transduction resulting in induction of apoptosis|down regulation of intrinsic apoptotic signaling pathway in response to DNA damage|downregulation of DNA damage response, signal transduction resulting in induction of apoptosis|downregulation of intrinsic apoptotic signaling pathway in response to DNA damage|down regulation of DNA damage response, signal transduction resulting in induction of apoptosis Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage. GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902231 up-regulation of DNA damage response, signal transduction resulting in induction of apoptosis|up-regulation of intrinsic apoptotic signaling pathway in response to DNA damage|activation of DNA damage response, signal transduction resulting in induction of apoptosis|upregulation of intrinsic apoptotic signaling pathway in response to DNA damage|positive regulation of DNA damage response, signal transduction resulting in induction of apoptosis|up regulation of DNA damage response, signal transduction resulting in induction of apoptosis|up regulation of intrinsic apoptotic signaling pathway in response to DNA damage|activation of intrinsic apoptotic signaling pathway in response to DNA damage|upregulation of DNA damage response, signal transduction resulting in induction of apoptosis Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage. CL:0000333 migratory neural crest cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000333 A cell derived from the specialized ectoderm flanking each side of the embryonic neural plate, which after the closure of the neural tube, forms masses of cells that migrate out from the dorsal aspect of the neural tube to spread throughout the body. GO:0050470 trimethylamine dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050470 UM-BBD_enzymeID:e0854|MetaCyc:1.5.8.2-RXN|RHEA:11864|EC:1.5.8.2 trimethylamine:electron-transferring flavoprotein oxidoreductase (demethylating)|TMADh activity Catalysis of the reaction: trimethylamine + H2O + electron-transferring flavoprotein = dimethylamine + formaldehyde + reduced electron-transferring flavoprotein. GO:0050473 arachidonate 15-lipoxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050473 Reactome:R-HSA-9028255|Reactome:R-HSA-2162002|Reactome:R-HSA-9018907|EC:1.13.11.33|Reactome:R-HSA-9020262|Reactome:R-HSA-2161951|Reactome:R-HSA-9020610|Reactome:R-HSA-9027607|Reactome:R-HSA-9026003|Reactome:R-HSA-9024881|Reactome:R-HSA-9020275|Reactome:R-HSA-9025152|RHEA:16869|Reactome:R-HSA-9024872|MetaCyc:ARACHIDONATE-15-LIPOXYGENASE-RXN|Reactome:R-HSA-9027532|Reactome:R-HSA-9027627|Reactome:R-HSA-9020261 linoleic acid omega6-lipoxygenase activity|15-lipoxygenase activity|arachidonate omega(6) lipoxygenase activity|omega6 lipoxygenase activity|arachidonate omega6 lipoxygenase activity|arachidonate:oxygen 15-oxidoreductase activity Catalysis of the reaction: arachidonate + O2 = (5Z,8Z,11Z,13E)-(15S)-15-hydroperoxyicosa-5,8,11,13-tetraenoate. GO:0050474 (S)-norcoclaurine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050474 RHEA:16173|MetaCyc:S-NORLAUDANOSOLINE-SYNTHASE-RXN|EC:4.2.1.78 (S)-norlaudanosoline synthase activity|4-hydroxyphenylacetaldehyde hydro-lyase [adding dopamine; (S)-norcoclaurine-forming]|4-hydroxyphenylacetaldehyde hydro-lyase (adding dopamine) Catalysis of the reaction: 4-(2-aminoethyl)benzene-1,2-diol + 4-hydroxyphenylacetaldehyde = (S)-norcoclaurine + H2O. GO:0050471 uracilylalanine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050471 MetaCyc:URACILYLALANINE-SYNTHASE-RXN|EC:2.5.1.53|RHEA:11496 O3-acetyl-L-serine:uracil 1-(2-amino-2-carboxyethyl)transferase activity|O(3)-acetyl-L-serine acetate-lyase (adding uracil) activity|Willardiine synthase activity|3-O-acetyl-L-serine:uracil 1-(2-amino-2-carboxyethyl)transferase activity|isowillardiine synthase activity|O3-acetyl-L-serine acetate-lyase (adding uracil) Catalysis of the reaction: O3-acetyl-L-serine + uracil = 3-(uracil-1-yl)-L-alanine + acetate. CHEBI:52582 isobacteriochlorins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52582 GO:0050472 zeatin reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050472 MetaCyc:ZEATIN-REDUCTASE-RXN|EC:1.3.1.69|RHEA:12757|KEGG_REACTION:R05702 dihydrozeatin:NADP+ oxidoreductase activity Catalysis of the reaction: dihydrozeatin + NADP(+) = H(+) + NADPH + zeatin. GO:0050488 ecdysteroid UDP-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050488 ecdysteroid UDP-glucosyl/UDP-glucuronosyl transferase activity Catalysis of the reaction: UDP-glucose + ecdysteroid = UDP + glucosyl-ecdysteroid. GO:0050489 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050489 GO:0050486 intramolecular transferase activity, transferring hydroxy groups biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050486 EC:5.4.4.- Catalysis of the transfer of a hydroxyl group from one position to another within a single molecule. GO:0050487 sulfoacetaldehyde acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050487 RHEA:24204|KEGG_REACTION:R05651|MetaCyc:RXN-2364|EC:2.3.3.15 sulphoacetaldehyde acetyltransferase activity|acetyl-phosphate:sulfite S-acetyltransferase (acyl-phosphate hydrolysing, 2-oxoethyl-forming) Catalysis of the reaction: acetyl phosphate + sulfite = phosphate + sulfoacetaldehyde. GO:1902238 regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902238 Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator. GO:1902239 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902239 inhibition of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator|down regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator|downregulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator|down-regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator. GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902236 downregulation of apoptosis in response to ER stress|down-regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|negative regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|down regulation of ER stress-induced apoptosis|down regulation of endoplasmic reticulum stress-induced apoptosis|down regulation of apoptosis triggered by ER stress|down regulation of apoptosis in response to ER stress|inhibition of endoplasmic reticulum stress-induced apoptosis|inhibition of apoptosis triggered by ER stress|inhibition of apoptosis in response to ER stress|downregulation of ER stress-induced apoptosis|inhibition of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|down regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|downregulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|down-regulation of ER stress-induced apoptosis|negative regulation of ER stress-induced apoptosis|down regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|down-regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|down-regulation of endoplasmic reticulum stress-induced apoptosis|negative regulation of endoplasmic reticulum stress-induced apoptosis|negative regulation of apoptosis triggered by ER stress|down-regulation of apoptosis triggered by ER stress|inhibition of ER stress-induced apoptosis|negative regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|down-regulation of apoptosis in response to ER stress|negative regulation of apoptosis in response to ER stress|downregulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|inhibition of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|downregulation of endoplasmic reticulum stress-induced apoptosis|downregulation of apoptosis triggered by ER stress Any process that stops, prevents or reduces the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway. GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902237 upregulation of ER stress-induced apoptosis|upregulation of endoplasmic reticulum stress-induced apoptosis|upregulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|upregulation of apoptosis triggered by ER stress|upregulation of apoptosis in response to ER stress|up-regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|up regulation of ER stress-induced apoptosis|activation of ER stress-induced apoptosis|positive regulation of ER stress-induced apoptosis|activation of endoplasmic reticulum stress-induced apoptosis|up-regulation of endoplasmic reticulum stress-induced apoptosis|activation of apoptosis triggered by ER stress|up regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|up-regulation of apoptosis triggered by ER stress|activation of apoptosis in response to ER stress|up-regulation of apoptosis in response to ER stress|activation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|upregulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|positive regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|up-regulation of ER stress-induced apoptosis|positive regulation of endoplasmic reticulum stress-induced apoptosis|positive regulation of apoptosis triggered by ER stress|up regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|positive regulation of apoptosis in response to ER stress|up regulation of endoplasmic reticulum stress-induced apoptosis|activation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|up-regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|up regulation of apoptosis triggered by ER stress|positive regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|up regulation of apoptosis in response to ER stress Any process that activates or increases the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway. CL:0000306 crystallin accumulating cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000306 lens cell GO:1902234 positive regulation of positive thymic T cell selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902234 upregulation of positive thymic T-lymphocyte selection|positive regulation of positive thymic T lymphocyte selection|up regulation of positive thymic T lymphocyte selection|up-regulation of positive thymic T-cell selection|activation of positive thymic T-cell selection|up-regulation of positive thymic T-lymphocyte selection|upregulation of positive thymic T cell selection|activation of positive thymic T-lymphocyte selection|upregulation of positive thymic T lymphocyte selection|positive regulation of positive thymic T-cell selection|up regulation of positive thymic T-cell selection|up-regulation of positive thymic T cell selection|activation of positive thymic T cell selection|positive regulation of positive thymic T-lymphocyte selection|up regulation of positive thymic T-lymphocyte selection|up-regulation of positive thymic T lymphocyte selection|activation of positive thymic T lymphocyte selection|upregulation of positive thymic T-cell selection|up regulation of positive thymic T cell selection Any process that activates or increases the frequency, rate or extent of positive thymic T cell selection. GO:1902235 regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902235 regulation of endoplasmic reticulum stress-induced apoptosis|regulation of apoptosis triggered by ER stress|regulation of apoptosis in response to ER stress|regulation of ER stress-induced apoptosis|regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|regulation of apoptosis in response to endoplasmic reticulum stress|regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress Any process that modulates the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway. GO:1902232 regulation of positive thymic T cell selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902232 regulation of positive thymic T lymphocyte selection|regulation of positive thymic T-cell selection|regulation of positive thymic T-lymphocyte selection Any process that modulates the frequency, rate or extent of positive thymic T cell selection. GO:1902233 negative regulation of positive thymic T cell selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902233 downregulation of positive thymic T cell selection|down regulation of positive thymic T cell selection|downregulation of positive thymic T lymphocyte selection|inhibition of positive thymic T cell selection|down regulation of positive thymic T lymphocyte selection|inhibition of positive thymic T lymphocyte selection|negative regulation of positive thymic T-cell selection|down-regulation of positive thymic T-cell selection|negative regulation of positive thymic T-lymphocyte selection|down-regulation of positive thymic T-lymphocyte selection|downregulation of positive thymic T-cell selection|downregulation of positive thymic T-lymphocyte selection|down-regulation of positive thymic T cell selection|down regulation of positive thymic T-cell selection|inhibition of positive thymic T-cell selection|down-regulation of positive thymic T lymphocyte selection|down regulation of positive thymic T-lymphocyte selection|negative regulation of positive thymic T lymphocyte selection|inhibition of positive thymic T-lymphocyte selection Any process that stops, prevents or reduces the frequency, rate or extent of positive thymic T cell selection. GO:1902241 copal-8-ol diphosphate(3-) metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902241 copal-8-ol diphosphate(3-) metabolism The chemical reactions and pathways involving copal-8-ol diphosphate(3-). GO:1902242 copal-8-ol diphosphate(3-) catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902242 copal-8-ol diphosphate(3-) degradation|copal-8-ol diphosphate(3-) breakdown|copal-8-ol diphosphate(3-) catabolism The chemical reactions and pathways resulting in the breakdown of copal-8-ol diphosphate(3-). GO:1902240 positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902240 up-regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator|upregulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator|up regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator|activation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator. CL:0000300 gamete biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000300 haploid germ cell|haploid nucleated cell A mature sexual reproductive cell having a single set of unpaired chromosomes. CL:0000301 pole cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000301 GO:0050480 imidazolonepropionase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050480 EC:3.5.2.7|KEGG_REACTION:R02288|MetaCyc:IMIDAZOLONEPROPIONASE-RXN|RHEA:23660 imidazolone propionic acid hydrolase activity|imidazolone-5-propionate hydrolase activity|4(5)-imidazolone-5(4)-propionic acid hydrolase activity|3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate amidohydrolase activity Catalysis of the reaction: (S)-3-(4-oxo-4,5-dihydro-1H-imidazol-5-yl)propanoic acid + H(2)O = N-formimidoyl-L-glutamate + H(+). GO:0050481 mandelate 4-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050481 KEGG_REACTION:R03794|EC:1.14.16.6|RHEA:21716|MetaCyc:MANDELATE-4-MONOOXYGENASE-RXN L-mandelate 4-hydroxylase activity|mandelic acid 4-hydroxylase activity|(S)-2-hydroxy-2-phenylacetate,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating) Catalysis of the reaction: (S)-mandelate + 5,6,7,8-tetrahydrobiopterin + O(2) = (S)-4-hydroxymandelate + 7,8-dihydrobiopterin + H(2)O. (S)-2-hydroxy-2-phenylacetate is also known as S-mandelate. CHEBI:52575 alkylglycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52575 GO:0050484 GMP 5'-nucleotidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050484 RHEA:27714|MetaCyc:RXN-7609 IMP-GMP specific 5'-nucleotidase activity|GMP 5' nucleotidase activity Catalysis of the reaction: 5'-GMP + H2O = guanosine + phosphate. CHEBI:52570 alpha-D-Galp-(1->3)-beta-D-Galp-(1->4)-beta-D-Glcp-(1<->1')-Cer biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52570 GO:0050485 oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050485 EC:1.21.4.- oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulphide as acceptor Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y and the acceptor is disulfide. GO:0050482 arachidonic acid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050482 The controlled release of arachidonic acid from a cell or a tissue. CHEBI:52572 acylglucosaminylphosphatidylinositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52572 GO:0050483 IMP 5'-nucleotidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050483 MetaCyc:RXN-7607|RHEA:27718 IMP-GMP specific 5'-nucleotidase activity|IMP 5' nucleotidase activity Catalysis of the reaction: 5'-IMP + H2O = inosine + phosphate. GO:0050499 oxidoreductase activity, acting on phosphorus or arsenic in donors, with NAD(P)+ as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050499 EC:1.20.1.- Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a NAD(P)+ to NAD(P)H. GO:0050497 transferase activity, transferring alkylthio groups biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050497 EC:2.8.4.- Catalysis of the transfer of an alkylthio group from one compound (donor) to another (acceptor). GO:0050498 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with 2-oxoglutarate as one donor, and the other dehydrogenated biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050498 EC:1.14.20.- Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and the latter donor is dehydrogenated. CHEBI:52567 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52567 CHEBI:52569 1-(alk-1-enyl)glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52569 CL:0000314 milk secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000314 GO:1902249 IMP binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1902249 Interacting selectively and non-covalently with IMP, inosine monophosphate. GO:1902247 geranylgeranyl diphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902247 geranylgeranyl diphosphate catabolism|geranylgeranyl diphosphate degradation|geranylgeranyl diphosphate breakdown The chemical reactions and pathways resulting in the breakdown of geranylgeranyl diphosphate. GO:1902248 5-O-phosphono-alpha-D-ribofuranosyl diphosphate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1902248 phosphoribosylpyrophosphate binding|5-phosphoribose 1-diphosphate binding Interacting selectively and non-covalently with 5-O-phosphono-alpha-D-ribofuranosyl diphosphate. CL:0000317 sebum secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000317 sebocyte A cell secreting sebun, an oily substance secreted by sebaceous glands, composed of keratin, fat, and cellular debris. GO:1902245 cis-abienol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902245 cis-abienol degradation|cis-abienol breakdown|cis-abienol catabolism The chemical reactions and pathways resulting in the breakdown of cis-abienol. CL:0000319 mucus secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000319 mucous cell GO:1902246 cis-abienol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902246 cis-abienol anabolism|cis-abienol synthesis|cis-abienol formation|cis-abienol biosynthesis The chemical reactions and pathways resulting in the formation of cis-abienol. GO:1902243 copal-8-ol diphosphate(3-) biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902243 copal-8-ol diphosphate(3-) anabolism|copal-8-ol diphosphate(3-) synthesis|copal-8-ol diphosphate(3-) formation|copal-8-ol diphosphate(3-) biosynthesis The chemical reactions and pathways resulting in the formation of copal-8-ol diphosphate(3-). GO:1902244 cis-abienol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902244 cis-abienol metabolism The chemical reactions and pathways involving cis-abienol. GO:1902252 positive regulation of erythrocyte apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902252 up regulation of erythrocyte apoptosis|positive regulation of red blood cell apoptotic process|positive regulation of erythrocyte apoptosis|up regulation of red blood cell apoptotic process|up-regulation of RBC apoptotic process|up regulation of erythrocyte apoptotic process|activation of erythrocyte apoptosis|activation of erythrocyte apoptotic process|upregulation of RBC apoptosis|upregulation of red blood cell apoptosis|upregulation of RBC apoptotic process|upregulation of red blood cell apoptotic process|up-regulation of erythrocyte apoptosis|up-regulation of red blood cell apoptosis|up regulation of RBC apoptosis|positive regulation of RBC apoptosis|up-regulation of erythrocyte apoptotic process|up-regulation of red blood cell apoptotic process|activation of red blood cell apoptotic process|upregulation of erythrocyte apoptosis|activation of red blood cell apoptosis|up regulation of RBC apoptotic process|activation of RBC apoptotic process|activation of RBC apoptosis|positive regulation of RBC apoptotic process|positive regulation of red blood cell apoptosis|upregulation of erythrocyte apoptotic process|up regulation of red blood cell apoptosis|up-regulation of RBC apoptosis Any process that activates or increases the frequency, rate or extent of erythrocyte apoptotic process. GO:1902253 regulation of intrinsic apoptotic signaling pathway by p53 class mediator biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902253 regulation of signal transduction by p53 class mediator resulting in induction of apoptosis|regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator. GO:1902250 regulation of erythrocyte apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902250 regulation of red blood cell apoptosis|regulation of red blood cell apoptotic process|regulation of RBC apoptosis|regulation of RBC apoptotic process|regulation of erythrocyte apoptosis Any process that modulates the frequency, rate or extent of erythrocyte apoptotic process. GO:1902251 negative regulation of erythrocyte apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902251 downregulation of red blood cell apoptosis|downregulation of erythrocyte apoptotic process|inhibition of RBC apoptosis|inhibition of RBC apoptotic process|down regulation of red blood cell apoptosis|downregulation of red blood cell apoptotic process|down-regulation of erythrocyte apoptosis|negative regulation of erythrocyte apoptosis|down regulation of red blood cell apoptotic process|down regulation of RBC apoptosis|inhibition of red blood cell apoptotic process|down-regulation of erythrocyte apoptotic process|inhibition of red blood cell apoptosis|downregulation of RBC apoptosis|down regulation of RBC apoptotic process|inhibition of erythrocyte apoptotic process|inhibition of erythrocyte apoptosis|downregulation of RBC apoptotic process|negative regulation of red blood cell apoptosis|down-regulation of RBC apoptosis|down-regulation of red blood cell apoptosis|negative regulation of RBC apoptosis|down regulation of erythrocyte apoptosis|negative regulation of RBC apoptotic process|negative regulation of red blood cell apoptotic process|down-regulation of red blood cell apoptotic process|down-regulation of RBC apoptotic process|downregulation of erythrocyte apoptosis|down regulation of erythrocyte apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of erythrocyte apoptotic process. CL:0000311 keratin accumulating cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000311 CL:0000312 keratinocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000312 malpighian cell|keratinized cell of epidermis An epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell. GO:0050491 sulcatone reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050491 EC:1.1.1.260|KEGG_REACTION:R05678|RHEA:24484|MetaCyc:1.1.1.260-RXN sulcatol:NAD+ oxidoreductase activity Catalysis of the reaction: NAD(+) + sulcatol = H(+) + NADH + sulcatone. GO:0050492 glycerol-1-phosphate dehydrogenase [NAD(P)+] activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050492 EC:1.1.1.261|RHEA:21412|MetaCyc:1.1.1.261-RXN sn-glycerol-1-phosphate:NAD(P)+ 2-oxidoreductase activity Catalysis of the reaction: NAD(P)+ + sn-glycerol-1-phosphate = NAD(P)H + H+ + dihydroxy-acetone-phosphate. CHEBI:52564 2-carboxy-4-methyl-5-[(2-phosphonooxy)ethylidene]-2,5-dihydrothiazole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52564 GO:0050490 1,4-lactonase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050490 EC:3.1.1.25|MetaCyc:14-LACTONASE-RXN|RHEA:12745 1,4-lactone hydroxyacylhydrolase activity|gamma-lactonase activity Catalysis of the reaction: H2O + a 1,4-lactone = a 4-hydroxyacid. CHEBI:52565 acylglycerophosphoserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52565 GO:0050495 peptidyl-glycyl-phosphatidylethanolamine biosynthetic process from peptidyl-glycine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050495 RESID:AA0346 peptidyl-glycyl-phosphatidylethanolamine synthesis from peptidyl-glycine|peptidyl-glycyl-phosphatidylethanolamine formation from peptidyl-glycine|peptidyl-glycyl-phosphatidylethanolamine anabolism from peptidyl-glycine The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-glycine ethanolamide-linked phosphatide following hydrolysis of a glycyl-peptide bond, as in the cleavage of arginine from the carboxy-terminal of Apg8 followed by its amidation with phosphatidylethanolamine. GO:0050496 peptidyl-L-glutamyl 5-omega-hydroxyceramide ester biosynthetic process from peptidyl-glutamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050496 RESID:AA0340 peptidyl-L-glutamyl 5-omega-hydroxyceramide ester anabolism from peptidyl-glutamine|peptidyl-L-glutamyl 5-omega-hydroxyceramide ester synthesis from peptidyl-glutamine|peptidyl-L-glutamyl 5-omega-hydroxyceramide ester formation from peptidyl-glutamine The modification of peptidyl-glutamine residues by deamidation and esterification with omega-hydroxyceramide. GO:0050493 GPI anchor biosynthetic process via N-threonyl-glycosylphosphatidylinositolethanolamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050493 RESID:AA0164 GPI anchor anabolism via N-threonyl-glycosylphosphatidylinositolethanolamine|GPI anchor synthesis via N-threonyl-glycosylphosphatidylinositolethanolamine|GPI anchor formation via N-threonyl-glycosylphosphatidylinositolethanolamine The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-threonyl ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a threonyl-peptide bond in the carboxy-terminal region of a membrane-associated protein. GO:0050494 GSI anchor biosynthetic process via N-glycyl-glycosylsphingolipidinositolethanolamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050494 RESID:AA0165 GSI anchor anabolism via N-glycyl-glycosylsphingolipidinositolethanolamine|GSI anchor synthesis via N-glycyl-glycosylsphingolipidinositolethanolamine|GSI anchor formation via N-glycyl-glycosylsphingolipidinositolethanolamine The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-glycine ethanolamide-linked glycosylsphingolipidinositol (GSI) anchor following hydrolysis of a glycyl-peptide bond in the carboxy-terminal region of a membrane-associated protein. CHEBI:76526 6-oxocyclohex-1-ene-1-carbonyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76526 CHEBI:76527 2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76527 CHEBI:76524 (3R,11Z,14Z)-3-hydroxyicosadienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76524 CHEBI:76529 glycerophosphoglycerophosphoglycerol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76529 CHEBI:76522 (3R,15Z)-3-hydroxytetracosenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76522 CHEBI:76523 (2E,15Z)-tetracosadienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76523 CHEBI:76520 (2E,13Z)-docosadienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76520 UBERON:0010091 future hindbrain meninx biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010091 future hindbrain meninges A multi-tissue structure that has the potential to develop into a meninx of hindbrain. CHEBI:76538 (2E,8Z,11Z,14Z)-icosatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76538 CHEBI:76535 [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76535 CHEBI:76536 (3R,8Z,11Z,14Z)-3-hydroxyicosatrienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76536 CHEBI:76539 [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n (1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76539 UBERON:0010092 future metencephalon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010092 A developing anatomical structure that has the potential to develop into a metencephalon. UBERON:0010096 future myelencephalon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010096 A developing anatomical structure that has the potential to develop into a myelencephalon. CHEBI:76530 sn-glycero-3-monophosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76530 PR:000000105 nodal protein biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000000105 NODAL A TGF-beta-like cystine-knot cytokine that is a translation product of the human NODAL gene or a 1:1 ortholog thereof. The nodal and lefty genes form positive and negative regulatory loops that resemble the reaction-diffusion system. As a pair, these genes control various events of vertebrate embryonic patterning, including left-right specification and mesoderm formation. CHEBI:76533 NDP-alpha-D-glucose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76533 CHEBI:76534 (11Z,14Z)-icosadienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76534 CHEBI:76532 (2E,11Z,14Z)-icosatrienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76532 CHEBI:76548 (11Z,14Z,17Z,20Z)-3-oxohexacosatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76548 CHEBI:76549 (3R,11Z,14Z,17Z,20Z)-3-hydroxyhexacosatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76549 CHEBI:76547 (2E,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76547 UBERON:0010083 future dermis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010083 Mesenchyme that has the potential to develop into a dermis. UBERON:0010084 future diaphragm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010084 A structure that will develop into a diaphragm. UBERON:0010081 future common hepatic duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010081 An extrahepatic bile duct that has the potential to develop into a common hepatic duct. UBERON:0009097 gravid organism biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009097 pregnant stage|gravid|pregnant adult|pregnant organism|pregnant adult stage An organism containing a developing embryo, fetus, or unborn offspring within the body. UBERON:0009098 gravid uterus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009098 womb The uterus in pregnancy CHEBI:76541 (3R,7Z,10Z,13Z,16Z)-3-hydroxydocosatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76541 CHEBI:76545 2-iminobutanoic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76545 CHEBI:76542 (2E,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76542 CHEBI:76543 (3R,9Z,12Z,15Z,18Z)-3-hydroxytetracosatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76543 CHEBI:76559 (13Z)-3-oxoicosenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76559 CHEBI:76557 (3R,11Z)-3-hydroxyoctadecenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76557 CHEBI:76558 (2E,11Z)-octadecadienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76558 UBERON:0010070 intermediate layer of tympanic membrane biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010070 intermediate fibrous layer of tympanic membrane|connective tissue layer of tympanic membrane|fibrous layer of tympanic membrane|fibrous stratum of tympanic membrane|tympanic endothelium The intermediate fibrous layer of the tympanic membrane. UBERON:0010071 layer of tympanic membrane biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010071 tympanic membrane layer UBERON:0010076 network of trabecular spaces in bone tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010076 trabecular space network|trabecular network of bone tissue Tissue cavity consisting of intercommunicating trabecular spaces in the cancellous bone. UBERON:0010077 cuboidal epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010077 An epithelium consisting of cuboidal epithelial cells. UBERON:0010074 chromaffin system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010074 argentaffin system|chromaffin tissue Organ system subdivision that consists primarily of chromaffin cells and their supporting structures. UBERON:0010075 sacral neural crest biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010075 One of the 5 distinct and partially overlapping functional domains of the premigratory neural crest. The vagal and sacral neural crest cells develop into the ganglia of the enteric nervous system, also known as the parasympathetic ganglia. PR:000014717 protein SET biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000014717 PHAPII|IGAAD|SET|I-2PP2A|TAF-I|template-activating factor I|inhibitor of granzyme A-activated DNase|HLA-DR-associated protein II|phosphatase 2A inhibitor I2PP2A A protein that is a translation product of the human SET gene or a 1:1 ortholog thereof. CHEBI:76552 (9Z,12Z)-hexadecadienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76552 CHEBI:76550 (2E,11Z,14Z,17Z,20Z)-hexacosapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76550 CHEBI:76555 (11Z)-3-oxooctadecenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76555 CHEBI:76556 (3R,15Z,18Z,21Z,24Z)-3-hydroxytriacontatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76556 CHEBI:76553 (3R,13Z,16Z,19Z,22Z)-3-hydroxyoctacosatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76553 CHEBI:76554 (2E,13Z,16Z,19Z,22Z)-octacosapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76554 GO:1990794 basolateral part of cell biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990794 The region of a cell situated by the cell sides which interface adjacent cells and near the base. Often used in reference to animal polarized epithelial cells. GO:1990795 rod bipolar cell terminal bouton biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990795 A specialized region of the axon terminus portion of a rod bipolar axon. A rod bipolar cell is a neuron found in the retina and having connections with rod photoreceptor cells and neurons in the inner plexiform layer. GO:1990796 photoreceptor cell terminal bouton biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990796 A specialized region of the axon terminus portion of a photoreceptor cell axon. A photoreceptor cell is a neuron specialized to detect and transduce light. CHEBI:76568 (3R,19Z,22Z,25Z,28Z)-3-hydroxytetratriacontatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76568 CHEBI:76569 (2E,19Z,22Z,25Z,28Z)-tetratriacontapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76569 GO:1990797 obsolete cholecystokinin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990797 CCK secretion OBSOLETE. The controlled release of cholecystokinin from a cell. Cholecystokinin is a peptide hormone that participates in pancreatic enzyme release in the gut and is also found in the brain. GO:1990790 response to glial cell derived neurotrophic factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990790 response to ATF|response to astrocyte-derived trophic factor|response to GDNF Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glial cell derived neurotrophic factor stimulus. GO:1990791 dorsal root ganglion development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990791 DRG development The process whose specific outcome is the progression of a dorsal root ganglion over time, from its formation to the mature structure. GO:1990792 cellular response to glial cell derived neurotrophic factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990792 cellular response to astrocyte-derived trophic factor|cellular response to GDNF|cellular response to ATF Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glial cell derived neurotrophic factor stimulus. GO:1990793 substance P secretion, neurotransmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990793 The controlled release of substance P by a cell, in which the substance P acts as a neurotransmitter. UBERON:6000002 tagma biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_6000002 The three main divisions of the whole organism formed from groups of segments. UBERON:6000006 head segment biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_6000006 Any segment that is part of some head. CHEBI:76562 (2E,13Z)-icosadienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76562 CHEBI:76563 (13Z)-icosenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76563 CHEBI:76560 (2E,15Z,18Z,21Z,24Z)-triacontapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76560 CHEBI:76561 (3R,13Z)-3-hydroxyicosenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76561 GO:1990798 pancreas regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990798 The regrowth of a destroyed pancreas. CHEBI:76566 (2E,17Z,20Z,23Z,26Z)-dotriacontapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76566 GO:1990799 mitochondrial tRNA wobble position uridine thiolation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990799 The process in which a uridine residue at position 34 in the anticodon of a mitochondrial tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from cysteine to position C2 by several steps. CHEBI:76567 polyunsaturated fatty acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76567 CHEBI:76564 (3R,17Z,20Z,23Z,26Z)-3-hydroxydotriacontatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76564 CHEBI:76565 2-ammonioprop-2-enoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76565 CHEBI:76579 triradylglycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76579 CHEBI:76570 (3R,21Z,24Z,27Z,30Z)-3-hydroxyhexatriacontatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76570 CHEBI:76571 (2E,21Z,24Z,27Z,30Z)-hexatriacontapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76571 CHEBI:76578 diradylglycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76578 CHEBI:76575 monoradylglycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76575 GO:0050400 xylitol kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050400 RHEA:20209|KEGG_REACTION:R02136|MetaCyc:XYLITOL-KINASE-RXN|EC:2.7.1.122 xylitol phosphotransferase activity|ATP:xylitol 5-phosphotransferase activity Catalysis of the reaction: ATP + xylitol = ADP + 2 H(+) + xylitol 5-phosphate. GO:0050401 xylonate dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050401 KEGG_REACTION:R02429|EC:4.2.1.82|MetaCyc:XYLONATE-DEHYDRATASE-RXN|RHEA:19157 D-xylonate hydro-lyase activity|D-xylo-aldonate dehydratase activity|D-xylonate hydro-lyase (2-dehydro-3-deoxy-D-xylonate-forming)|D-xylonate dehydratase activity Catalysis of the reaction: D-xylonate = 2-dehydro-3-deoxy-D-arabinonate + H(2)O. GO:0050404 zeatin O-beta-D-xylosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050404 KEGG_REACTION:R02119|MetaCyc:ZEATIN-O-BETA-D-XYLOSYLTRANSFERASE-RXN|RHEA:14721|EC:2.4.2.40 zeatin O-b-D-xylosyltransferase activity|UDP-D-xylose:zeatin O-beta-D-xylosyltransferase activity|zeatin O-xylosyltransferase activity|uridine diphosphoxylose-zeatin xylosyltransferase activity Catalysis of the reaction: UDP-alpha-D-xylose + zeatin = O-beta-D-xylosylzeatin + H(+) + UDP. GO:0050405 [acetyl-CoA carboxylase] kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050405 RHEA:20333|MetaCyc:2.7.11.27-RXN|EC:2.7.11.27 acetyl-CoA carboxylase kinase (AMP-activated) activity|ATP:acetyl-CoA carboxylase phosphotransferase activity|acetyl coenzyme A carboxylase kinase (phosphorylating) activity|STK5|acetyl-coenzyme A carboxylase kinase activity|acetyl-CoA carboxylase kinase (cAMP-independent) activity|ACK3|ACK2|acetyl-CoA carboxylase bound kinase activity|AMPK|acetyl-CoA carboxylase kinase-2 activity|I-peptide kinase activity|acetyl-CoA carboxylase kinase activity|acetyl-CoA carboxylase kinase-3 (AMP-activated) activity|acetyl-CoA carboxylase kinase 2 activity Catalysis of the reaction: ATP + [acetyl-CoA carboxylase] = ADP + [acetyl-CoA carboxylase] phosphate. GO:0050402 xylono-1,4-lactonase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050402 MetaCyc:XYLONO-14-LACTONASE-RXN|EC:3.1.1.68|RHEA:18341 xylonolactonase activity|D-xylono-1,4-lactone lactonohydrolase activity|xylono-g-lactonase activity Catalysis of the reaction: D-xylono-1,4-lactone + H2O = D-xylonate. GO:0050403 trans-zeatin O-beta-D-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050403 MetaCyc:RXN-4723|KEGG_REACTION:R02118|RHEA:23224|EC:2.4.1.203 UDP-glucose:trans-zeatin O-beta-D-glucosyltransferase activity|zeatin O-b-D-glucosyltransferase activity|uridine diphosphoglucose-zeatin O-glucosyltransferase activity|UDPglucose:trans-zeatin O-beta-D-glucosyltransferase activity|zeatin O-glucosyltransferase activity|zeatin O-beta-D-glucosyltransferase activity Catalysis of the reaction: trans-zeatin + UDP-D-glucose = O-beta-D-glucosyl-trans-zeatin + H(+) + UDP. GO:0050408 [pyruvate kinase]-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050408 EC:3.1.3.49|MetaCyc:PYRUVATE-KINASE-PHOSPHATASE-RXN pyruvate kinase phosphatase activity|ATP:pyruvate 2-O-phosphotransferase-phosphate phosphohydrolase activity|pyruvate kinase-phosphatase activity Catalysis of the reaction: [pyruvate kinase] phosphate + H2O = [pyruvate kinase] + phosphate. GO:0050409 indolylacetylinositol arabinosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050409 MetaCyc:2.4.2.34-RXN|EC:2.4.2.34|KEGG_REACTION:R04335|RHEA:19505 UDP-L-arabinose:(indol-3-yl)acetyl-myo-inositol L-arabinosyltransferase activity|arabinosylindolylacetylinositol synthase activity|UDP-L-arabinose:indol-3-ylacetyl-myo-inositol L-arabinosyltransferase activity Catalysis of the reaction: 1L-1-O-(indol-3-yl)acetyl-myo-inositol + UDP-L-arabinose = (indol-3-yl)acetyl-myo-inositol 3-L-arabinoside + H(+) + UDP. GO:0050406 [acetyl-CoA carboxylase]-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050406 MetaCyc:ACETYL-COA-CARBOXYLASE-PHOSPHATASE-RXN|EC:3.1.3.44|RHEA:17125 acetyl-CoA carboxylase-phosphatase activity|acetyl-CoA:carbon-dioxide ligase (ADP-forming)-phosphate phosphohydrolase activity Catalysis of the reaction: [acetyl-CoA carboxylase]-phosphate + H2O = [acetyl-CoA carboxylase] + phosphate. GO:0050407 [glycogen-synthase-D] phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050407 MetaCyc:GLYCOGEN-SYNTHASE-D-PHOSPHATASE-RXN|EC:3.1.3.42 UDP-glucose:glycogen 4-alpha-D-glucosyltransferase-D phosphohydrolase activity|glycogen synthase phosphatase activity|uridine diphosphoglucose-glycogen glucosyltransferase phosphatase activity|glycogen-synthase-D phosphatase activity|glycogen synthase D phosphatase activity|UDPglucose-glycogen glucosyltransferase phosphatase activity|glycogen glucosyltransferase phosphatase activity|UDPglucose:glycogen 4-alpha-D-glucosyltransferase-D phosphohydrolase activity|phosphatase type 2oC|glycogen synthetase phosphatase activity|Mg2+ dependent glycogen synthase phosphatase activity|UDP-glycogen glucosyltransferase phosphatase activity Catalysis of the reaction: [glycogen-synthase D] + H2O = [glycogen-synthase I] + phosphate. CL:0000385 prohemocyte (sensu Nematoda and Protostomia) biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000385 CL:0000386 attachment cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000386 CL:0000387 hemocyte (sensu Arthropoda) biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000387 CL:0000388 tendon cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000388 tenocyte|muscle attachment cell An elongated fibrocyte that is part of a tendon. The cytoplasm is stretched between the collagen fibres of the tendon. They have a central cell nucleus with a prominent nucleolus. Tendon cells have a well-developed rough endoplasmic reticulum and they are responsible for synthesis and turnover of tendon fibres and ground substance. CHEBI:76581 2-alkylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76581 CHEBI:76584 monoalkyldiacylglycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76584 CHEBI:76585 1-alkyl-2,3-diacyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76585 CHEBI:76582 monoalkylmonoacylglycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76582 CHEBI:76583 alk-1-enylacylglycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76583 CL:0000381 neurosecretory neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000381 GO:0050411 agaritine gamma-glutamyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050411 EC:2.3.2.9|MetaCyc:AGARITINE-GAMMA-GLUTAMYLTRANSFERASE-RXN (gamma-L-glutamyl)-N1-(4-hydroxymethylphenyl)hydrazine:(acceptor) gamma-glutamyltransferase activity|(gamma-L-glutamyl)-1-N-(4-hydroxymethylphenyl)hydrazine:(acceptor) gamma-glutamyltransferase activity|agaritine g-glutamyltransferase activity Catalysis of the reaction: agaritine + acceptor-NH2 = 4-hydroxymethylphenylhydrazine + gamma-L-glutamyl-acceptor. GO:0050412 cinnamate beta-D-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050412 KEGG_REACTION:R02256|EC:2.4.1.177|MetaCyc:CINNAMATE-GLUCOSYLTRANSFERASE-RXN|RHEA:13437 UDPG:t-cinnamate glucosyltransferase activity|UDP-glucose:trans-cinnamate beta-D-glucosyltransferase activity|cinnamate b-D-glucosyltransferase activity|uridine diphosphoglucose-cinnamate glucosyltransferase activity|cinnamate glucosyltransferase activity|UDPglucose:trans-cinnamate beta-D-glucosyltransferase activity Catalysis of the reaction: trans-cinnamate + UDP-D-glucose = 1-O-trans-cinnamoyl-beta-D-glucopyranose + UDP. GO:0050410 3-oxolaurate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050410 RHEA:13385|MetaCyc:3-OXOLAURATE-DECARBOXYLASE-RXN|EC:4.1.1.56|KEGG_REACTION:R03747 3-oxododecanoate carboxy-lyase (2-undecanone-forming)|beta-ketoacyl decarboxylase activity|3-oxododecanoate carboxy-lyase activity|beta-ketolaurate decarboxylase activity Catalysis of the reaction: 3-oxolaurate + H(+) = 2-undecanone + CO(2). GO:0050415 formimidoylglutamase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050415 MetaCyc:FORMIMINOGLUTAMASE-RXN|EC:3.5.3.8|KEGG_REACTION:R02285|RHEA:22492 formiminoglutamase activity|N-formimidoyl-L-glutamate formimidoylhydrolase activity|N-formiminoglutamate hydrolase activity|formiminoglutamate hydrolase activity|N-formimino-L-glutamate formiminohydrolase activity Catalysis of the reaction: N-formimidoyl-L-glutamate + H(2)O = L-glutamate + formamide. GO:0050416 formimidoylglutamate deiminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050416 EC:3.5.3.13|MetaCyc:FORMIMINOGLUTAMATE-DEIMINASE-RXN|RHEA:22832 formiminoglutamic iminohydrolase activity|formiminoglutamate deiminase activity|N-formimidoyl-L-glutamate iminohydrolase activity Catalysis of the reaction: N-formimidoyl-L-glutamate + H2O = N-formyl-L-glutamate + NH3. GO:0050413 D-alanine 2-hydroxymethyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050413 RHEA:10064|EC:2.1.2.7|MetaCyc:D-ALANINE-HYDROXYMETHYLTRANSFERASE-RXN|KEGG_REACTION:R01225 5,10-methylenetetrahydrofolate:D-alanine 2-hydroxymethyltransferase activity|2-methylserine hydroxymethyltransferase activity|D-alanine hydroxymethyltransferase activity Catalysis of the reaction: 5,10-methylenetetrahydrofolate + D-alanine + H(2)O = (6S)-5,6,7,8-tetrahydrofolate + 2-methylserine. GO:0050414 formimidoylaspartate deiminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050414 EC:3.5.3.5|RHEA:13661|MetaCyc:FORMIMINOASPARTATE-DEIMINASE-RXN N-formimidoyl-L-aspartate iminohydrolase activity|formiminoaspartate deiminase activity Catalysis of the reaction: N-formimidoyl-L-aspartate + H2O = N-formyl-L-aspartate + NH3. GO:0050419 hydroxymandelonitrile lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050419 EC:4.1.2.11|RHEA:15977|MetaCyc:HYDROXYMANDELONITRILE-LYASE-RXN hydroxynitrile lyase activity|(S)-4-hydroxymandelonitrile 4-hydroxybenzaldehyde-lyase (cyanide-forming)|(S)-4-hydroxymandelonitrile hydroxybenzaldehyde-lyase activity|sorghum hydroxynitrile lyase activity Catalysis of the reaction: 4-hydroxymandelonitrile = 4-hydroxybenzaldehyde + hydrocyanate. GO:0050417 glutamin-(asparagin-)ase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050417 MetaCyc:GLUTAMINASE-ASPARAGIN-ASE-RXN|EC:3.5.1.38 L-ASNase/L-GLNase activity|L-asparagine/L-glutamine amidohydrolase activity|glutaminase-asparaginase activity|L-glutamine(L-asparagine) amidohydrolase activity|glutaminase-(asparagin-)ase activity Catalysis of the reaction: H2O + L-glutamine = NH3 + L-glutamate; and H2O + L-asparagine = NH3 + L-aspartate. GO:0050418 hydroxylamine reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050418 RHEA:22052|EC:1.7.99.1|MetaCyc:HYDROXYLAMINE-REDUCTASE-RXN ammonia:(acceptor) oxidoreductase activity|hydroxylamine (acceptor) reductase activity|ammonia:acceptor oxidoreductase activity Catalysis of the reaction: NH3 + H2O + acceptor = hydroxylamine + reduced acceptor. CL:0000394 plasmatocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000394 CL:0000396 lamellocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000396 CL:0000397 ganglion interneuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000397 CHEBI:76591 (25R)-cholest-5-ene-3beta,26-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76591 CHEBI:76592 (25R)-7alpha,26-dihydroxycholesterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76592 CHEBI:76590 1-organyl-2-lyso-sn-glycero-3-phospholipid(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76590 CHEBI:76595 nephroprotective agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76595 CHEBI:76596 ADP-D-ribose 1'',2''-cyclic phosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76596 CHEBI:76593 1-acyl-2-[(Z)-9,10-enoyl]-sn-glycero-3-phospholipid(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76593 CHEBI:76594 1-acyl-2-(9,10-methyleneacyl)-sn-glycero-3-phospholipid(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76594 CL:0000390 blood cell (sensu Nematoda and Protostomia) biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000390 CL:0000391 podocyte (sensu Diptera) biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000391 An insect immune cell that develops from plasmatocyte. CL:0000392 crystal cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000392 CL:0000393 electrically responsive cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000393 A cell whose function is determined by its response to an electric signal. GO:1990750 obsolete axon shaft biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990750 axonal shaft OBSOLETE. Main portion of an axon, excluding terminal, spines, or dendrites. CHEBI:27515 alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-Gal-D-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27515 GO:1990751 Schwann cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990751 The directed movement of a Schwann cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). CHEBI:27517 (1->2)-beta-D-glucan biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27517 GO:1990752 microtubule end biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990752 Any end of a microtubule. Microtubule ends differ in that the so-called microtubule plus-end is the one that preferentially grows by polymerization, with respect to the minus-end. GO:1990753 equatorial cell cortex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990753 The region of the cell cortex in a mitotically dividing cell that flanks the central spindle and corresponds to the site of actomyosin ring formation that results in cleavage furrow formation and ingression. CHEBI:27518 acetylene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27518 CHEBI:27512 (2R,3R)-2,3-dihydroxy-3-methylpentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27512 CHEBI:27513 precorrin-6X biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27513 CHEBI:27514 genistein 7-O-beta-D-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27514 UBERON:0010143 seminal vesicle fluid biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010143 vesicular fluid|secretion of seminal vesicle|seminal vesicle secretion|seminal fluid A bodily secretion that is produced by a seminal vesicle. CHEBI:27510 umbelliferone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27510 UBERON:0010141 primitive sex cord of indifferent gonad biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010141 indifferent sex cord|primitive sex cords A sex cord that is part of a indifferent gonad. UBERON:0010147 male accessory sex gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010147 male accessory gland|male accessory reproductive gland Any gland, other than the gonad, associated with the genital tract, such as the ampulla of the ductus deferens and the bulbourethral, prostate and vesicular glands of the male. UBERON:0010137 polarized epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010137 A polarized epithelium is an epithelium where the epithelial sheet is oriented with respect to the planar axis. NCBITaxon:50557 Insecta organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_50557 true insects GO:1990758 mitotic sister chromatid biorientation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990758 The mitotic cell cycle process in which sister chromatids establish stable, end-on attachments to the plus ends of microtubules emanating from opposite spindle poles, oriented such that separation can proceed. This is the final step in metaphase plate congression. GO:1990759 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990759 GO:1990754 obsolete GABAergic neuronal action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990754 GABAergic neuronal action potential OBSOLETE. An action potential that occurs in a GABAergic neuron. GO:1990755 mitotic spindle microtubule depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990755 mitotic spindle microtubule depolymerisation The removal of tubulin heterodimers from one or both ends of a microtubule that is part of the mitotic spindle. GO:1990756 ubiquitin ligase-substrate adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990756 protein binding, bridging involved in substrate recognition for ubiquitination|ubiquitin ligase substrate adaptor The binding activity of a molecule that brings together a ubiquitin ligase and its substrate. Usually mediated by F-box BTB/POZ domain proteins. GO:1990757 ubiquitin ligase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990757 mitotic anaphase-promoting complex activator activity Binds to and increases the activity of a ubiquitin ligase. GO:1990761 growth cone lamellipodium biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990761 A thin sheetlike process extended by the leading edge of an axonal or dendritic growth cone; contains a dense meshwork of actin filaments. GO:1990762 cytoplasmic alanyl-tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990762 The process of coupling alanine to alanyl-tRNA, catalyzed by alanyl-tRNA synthetase involved in cytoplasmic translation. GO:1990763 arrestin family protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990763 Interacting selectively and non-covalently with any member of the arrestin family, proteins involved in agonist-mediated desensitization of G protein-coupled receptors. GO:1990764 myofibroblast contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990764 MFB contraction|MF contraction The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a myofibroblast. CHEBI:27522 rutinose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27522 GO:1990760 osmolarity-sensing cation channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990760 Enables the transmembrane transfer of a cation by a channel that opens when a change in the osmolarity occurs in the extracellular space of the cell in which the cation channel resides. UBERON:0009141 craniocervical region vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009141 vein of head and neck|craniocervical vein|head and neck veins A vein that is part of a craniocervical region. UBERON:0010131 conducting tissue of heart biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010131 specialized conducting tissue of heart|specialized muscle tissue of heart Any portion of cardiac muscle tissue that is part of the conducting system of heart or the Purkinje fibers. UBERON:0010130 embryonic autopod plate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010130 autopod plate|limb plate The distal elements of the developing limb of vertebrates that will give rise to the autopod (e.g. manus, pes, paw) UBERON:0010135 sensory circumventricular organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010135 humerosensory system organ|humerosensory circumventricular organ|sensitive circumventricular organs|sensory CVOs|sensory circumventricular organs|humerosensory system|sensitive organs A circumventricular organ that is capable of monitoring the levels of substances to the cerebrospinal fluid. UBERON:0010136 epithelial sheet biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010136 An epithelial sheet is a flat surface consisting of closely packed epithelial cells. UBERON:0010133 neuroendocrine gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010133 neuroendocrine system gland any of the organized aggregations of cells that function as secretory or excretory organs and that release hormones in response to neural stimuli UBERON:0010134 secretory circumventricular organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010134 A circumventricular organ that is capable of secreting substances into the cerebrospinal fluid. UBERON:0010129 femur cartilage element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010129 femoral cartilage condensation A femur endochondral element that is composed primarily of cartilage tissue. UBERON:0010126 future nucleus ambiguus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010126 A gray matter that has the potential to develop into a nucleus ambiguus. UBERON:0010127 future dorsal motor nucleus of vagus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010127 A gray matter that has the potential to develop into a dorsal motor nucleus of vagus nerve. GO:1990769 proximal neuron projection biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990769 The portion of an axon or dendrite that is close to the neuronal cell body. UBERON:0009142 entire embryonic mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009142 Sum total of mesenchyme in the embryo. UBERON:0009145 pharyngeal region of foregut biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009145 pharyngeal region GO:1990765 colon smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990765 A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry of the large intestine, exclusive of the rectum. The colon is that part of the large intestine that connects the small intestine to the rectum. GO:1990766 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990766 GO:1990767 prostaglandin receptor internalization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990767 The process that results in the uptake of a prostaglandin receptor into an endocytic vesicle. GO:1990768 gastric mucosal blood circulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990768 stomach mucosal blood circulation The flow of blood through the gastric mucosa of an animal, enabling the transport of nutrients and the removal of waste products. UBERON:0009149 foramen primum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009149 primary interatrial foramen|interatrial foramen primum|ostium primum opening in the septum primum between the two atria of the embryonic heart[TMD]. GO:1990772 substance P secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990772 The regulated release of substance P, a peptide hormone that is involved in neurotransmission, inflammation, and antimicrobial activity. GO:1990773 matrix metallopeptidase secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990773 MMP secretion|matrix metalloproteinase secretion The regulated release of matrix metallopeptidases, a family of zinc-dependent endopeptidases that can degrade extracellular matrix proteins and process other types of proteins. GO:1990774 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990774 GO:1990775 endothelin production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_1990775 endothelin-1 secretion|endothelin secretion|endothelin-2 production|endothelin-3 production|EDN1 production|EDN2 production|EDN3 production The appearance of a endothelin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. GO:1990770 small intestine smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990770 A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry in the intestine between the stomach and the large intestine. GO:1990771 clathrin-dependent extracellular exosome endocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990771 clathrin-mediated extracellular exosome endocytosis|exosome related The clathrin-mediated endocytosis of an extracellular exosome. UBERON:0010124 future inferior salivatory nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010124 A gray matter that has the potential to develop into a inferior salivatory nucleus. UBERON:0010125 future superior salivatory nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010125 A gray matter that has the potential to develop into a superior salivatory nucleus. UBERON:0010123 future facial nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010123 A gray matter that has the potential to develop into a facial nucleus. UBERON:0009133 pleuroperitoneal membrane biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009133 pleuroperitoneal membranes|pleuroperitoneal fold A fold of tissue which extends into the peritoneal cavity of the developing embryo and participates in the separation of the pleural and peritoneal cavities. GO:1990776 response to angiotensin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990776 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an angiotensin stimulus. Angiotensin is any of three physiologically active peptides (angiotensin II, III, or IV) processed from angiotensinogen. GO:1990777 lipoprotein particle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990777 A spherical particle containing non-covalently associated proteins and lipids. Examples are plasma lipoprotein particles which transport lipids in the blood or lymph. GO:1990778 protein localization to cell periphery biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990778 A process in which a protein is transported to, or maintained in, the cell periphery. GO:1990779 glycoprotein Ib-IX-V complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990779 IntAct:EBI-10727454|IntAct:EBI-10728062 GPIb-IX-V complex|GPIb-V-IX complex|CD42 A transmembrane signalling receptor complex found exclusively on platelets. Involved in haemostasis and thrombosis where it aids blood coagulation. GO:1990783 periphagosomal region of cytoplasm biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990783 Cytoplasm situated near, or occurring around, a phagosome. CHEBI:27504 mitomycin C biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27504 GO:1990784 response to dsDNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990784 response to double-stranded DNA Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded DNA stimulus. CHEBI:27505 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-en-26-oyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27505 GO:1990785 response to water-immersion restraint stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990785 response to immobilization stress combined with water immersion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of water immersion while being held immobile. GO:1990786 cellular response to dsDNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990786 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded DNA stimulus. GO:1990780 cytoplasmic side of dendritic spine plasma membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990780 The leaflet of the plasma membrane that faces the cytoplasm and any proteins embedded or anchored in it or attached to its surface surrounding a dendritic spine. GO:1990781 response to immobilization stress combined with electrical stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990781 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus given while being held immobile. CHEBI:27503 aldehydo-D-mannosamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27503 GO:1990782 protein tyrosine kinase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990782 tyrosine kinase binding Interacting selectively and non-covalently with protein tyrosine kinase. UBERON:0009128 lateral line placode biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009128 lateral line placodes An ectodermal placode that will develop into the components of the lateral line system UBERON:0009129 right atrium endocardium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009129 right atrial endocardium|endocardium of right atrium|right atrium endocardial tissue Endocardium that is part of the right atrium. UBERON:0009122 adenohypophyseal placode biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009122 pituitary placode The adenohypophyseal placode forms the anterior lobe of the pituitary gland and gives rise to the endocrine secretory cells of the pituitary UBERON:0009124 geniculate placode biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009124 hyoid placode|facial placode|hyoid VII placode|facial epibranchial placode|epibranchial placode 1|facial VII placode Rostralmost epibranchial placode. Associated with 1st branchial cleft. GO:1990787 negative regulation of hh target transcription factor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990787 IntAct:EBI-10170144 negative regulation of hedgehog target transcription factor Any process that decreases the activity of a transcription factor that activates transcription of Hedgehog-target genes in response to Smoothened signaling. In Drosophila, Cubitus interruptus (Ci) is the only identified transcription factor so far in the Hedgehog signaling pathway. In vertebrates members of the Gli protein family are activated by Hedgehog signaling. GO:1990788 GLI-SUFU complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990788 IntAct:EBI-10170144|IntAct:EBI-10828915|IntAct:EBI-10828948|IntAct:EBI-10828976|IntAct:EBI-10828997|IntAct:EBI-10829035 A protein repressing GLI's transcription factor activity when SMO signalling is inactive. Upon ligand binding to the upstream receptor PTC (Patched) GLI dissociates from SUFU and activates transcription of hedgehog-target genes. In mammals it consists of SUFU and one of the GLI family proteins. UBERON:0009125 petrosal placode biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009125 glossopharyngeal placode|glossopharyngeal epibranchial placode|epibranchial placode 2|glossopharyngeal IX placode Epibranchial placode between geniculate and nodose. Associated with 2nd branchial cleft. GO:1990789 thyroid gland epithelial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990789 thyroid follicular cell proliferation|Hurthle cell proliferation The multiplication or reproduction of thyroid gland epithelial cells, resulting in the expansion of the thyroid gland epithelial cell population. UBERON:0009127 epibranchial ganglion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009127 epibranchial ganglia Cranial ganglion which develops from an epibranchial placode. UBERON:0009191 sphenoid bone pre-cartilage condensation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009191 A sphenoid endochondral element that is composed primarily of a pre-cartilage condensation. UBERON:0009193 sphenoid cartilage element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009193 sphenoid bone cartilage condensation A sphenoid endochondral element that is composed primarily of cartilage tissue. UBERON:0010183 liver trabecula biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010183 hepatic trabecula A trabecula that is part of a liver UBERON:0009196 indifferent external genitalia biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009196 UBERON:0010186 male urethral gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010186 urethral gland (male)|gland of male urethra|Littre's gland|gland of Littre|male urethra gland|glandulae urethrales urethrae masculinae any of the numerous small mucous-secreting glands located in the wall of the penile urethra UBERON:0010187 female urethral gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010187 urethral gland (female)|gland of female urethra|female urethra gland An urethral gland that is part of a female urethra. UBERON:0010188 protuberance biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010188 A roughly circular bulge in a surface. UBERON:0010189 right atrium venous valve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010189 right venous valve PO:0009020 meristem L1 layer biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009020 分裂組織 L1 (Japanese, exact)|meristema L1 (Spanish, exact)|tunica (related) A portion of meristem tissue (PO:0009013) that is the outermost layer of a shoot apical meristem (PO:0020148) and gives rise to a shoot system epidermis (PO:0006035). CHEBI:600520 micafungin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_600520 GO:1990718 axonemal central pair projection biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990718 Part of the 9+2 axoneme, that occurs in most motile cilia, consisting of the projections off of the central pair of single microtubules. GO:1990719 C1 axonemal microtubule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990719 C1 tubule One of two microtubules present in the axonemal central pair. It is distinguishable from the C2 axonemal microtubule (also called C2 tubule) by the presence of differing protein components of the projections. PO:0009027 megasporophyll biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009027 megasporofilo (Spanish, exact)|大胞子葉 (Japanese, exact)|macrosporophyll (related)|cone scale (narrow)|ovuliferous scale (narrow) A structure upon which (or in the axil of which) one or more megasporangia are borne; in flowering plants, a carpel. GO:1990714 hydroxyproline O-galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990714 HPGT Catalysis of the transfer of galactose from UDP-galactose to hydroxyproline residues present in the peptide backbone. UBERON:0009198 craniofacial suture biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009198 joint of the skull bones|articulation of skull bones Any suture between cranial and/or facial bones. PO:0009028 microsporophyll biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009028 microsporofilo (Spanish, exact)|小胞子葉 (Japanese, exact) A structure on which one or more microsporangia are borne; in flowering plants, the stamen. GO:1990715 mRNA CDS binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990715 mRNA coding sequence binding|mRNA coding region binding Interacting selectively and non-covalently with the coding sequence (CDS) of an mRNA molecule. UBERON:0009199 facial suture biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009199 Any suture between facial bones. GO:1990716 axonemal central apparatus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990716 Part of the 9+2 axoneme, that occurs in most motile cilia, consisting of the pair of two single central microtubules and their associated structures which include the central pair projections, the central pair bridges linking the two tubules, and the central pair caps which are attached to the distal or plus ends of the microtubules. PO:0009029 stamen biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009029 Zea stamen (narrow)|estambre (Spanish, exact)|Poaceae stamen (narrow)|雄蕊 (Japanese, exact) A microsporophyll bearing one or more microsporangia. GO:1990717 axonemal central bridge biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990717 Part of the 9+2 axoneme, that occurs in most motile cilia, consisting of the two bridges which connect the central pair of single microtubules. GO:1990710 MutS complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990710 IntAct:EBI-10705937 MutS mismatch repair complex A homodimeric mismatch repair complex involved in binding to and correcting insertion/deletion mutations. GO:1990711 beta-catenin-ICAT complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990711 IntAct:EBI-10691252|IntAct:EBI-10705284 CTNNB1-CTNNBIP1 complex|Beta-catenin-ICAT complex Transcription factor complex that inhibits binding of Tcf to beta-catenin while preserving interaction of catenin with cadherin thus inhibiting transcription mediated by beta-catenin-Tcf complex. PO:0009025 vascular leaf biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009025 foliage leaf (exact)|ascidium (narrow)|macrophyll (related)|vascular leaves (exact, plural)|pitcher-blade (narrow)|frond (narrow)|trophophyll (narrow)|megaphyll (related)|fiddlehead (narrow)|scale-like leaf (narrow)|leaf, vascular (exact)|ascidia (narrow)|pitcher blade (narrow)|hoja vascular (Spanish, exact)|needle-like leaf (narrow)|sterile frond (narrow)|pitcher (narrow)|crozier (related)|維管束のある葉, または維管束植物の葉 (Japanese, exact) A leaf (PO:0025034) in a vascular plant. GO:1990712 HFE-transferrin receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990712 A protein complex containing at least HFE and a transferrin receptor (either TFR1/TFRC or TFR2), proposed to play a role in the sensing of transferrin-bound Fe (Fe2-Tf) on the plasma membrane to regulate hepcidin transcription. GO:1990713 survivin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990713 IntAct:EBI-10727115|IntAct:EBI-10714791 survivin homodimer complex|Baculoviral IAP repeat-containing protein 5 complex A protein complex that negatively regulates apoptotic processes. In human, this anti-apoptotic complex is a homodimer of BIRC5 (survivin) and provides one survivin molecule to the chromosomal passenger complex (CPC). PO:0009026 sporophyll biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009026 胞子葉 (Japanese, exact)|spore leaf (exact)|esporofilo (Spanish, exact) A leaf-like organ on which one or more sporangia are borne. GO:1990720 C2 axonemal microtubule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990720 C2 tubule One of two microtubules present in the axonemal central pair. It is distinguishable from the C1 axonemal microtubule (also called C1 tubule) by the presence of differing protein components of the projections. UBERON:0010171 strand of hair of face biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010171 facial hair|hair of face|face hair|face hair strand A strand of hair that is part of a face. PO:0009009 plant embryo biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009009 germ (related)|植物胚 (Japanese, exact)|embryo (broad)|embrión (Spanish, exact) A whole plant (PO:0000003) that participates in the plant embryo stage (PO:0007631). UBERON:0010172 bulb of aorta biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010172 supraaortic valve area|bulbus aortae|root of aorta|aortic bulb|aorta bulb|aortic root|bulb of ascending aorta The portion of the left ventricular outflow tract delineated by the sinotubular ridge superiorly and the bases of the valve leaflets inferiorly; it comprises the aortic sinuses, the aortic valve leaflets, the commissures, and the interleaflet triangles OPL:0000102 Leishmania major metacyclic promastigote stage biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OPL_0000102 A metacyclic promastigote stage in the lifecycle of Leishmania major. PO:0009010 seed biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009010 種子 (Japanese, exact)|pyrene (narrow)|semilla (Spanish, exact)|diaspore (broad) A multi-tissue plant structure (PO:0025496) that develops from a plant ovule (PO:0020003) and has as parts a plant embryo (PO:0009009) enclosed in a seed coat (PO:0009088). PO:0009011 plant structure biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009011 植物 構造 (Japanese, exact)|estructura vegetal (Spanish, exact) A plant anatomical entity (PO:0025131) that is, or was, part of a plant, or was derived from a part of a plant. GO:1990729 primary miRNA modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990729 The covalent alteration of one or more nucleotides within a primary miRNA molecule to produce a primary miRNA molecule with a sequence that differs from that coded genetically. GO:1990725 cord factor receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990725 Wikipedia:Cord_factor trehalose 6,6'-dimycolate receptor activity|TMD receptor activity Combining with a cord factor, an M. tuberculosis cell wall glycolipid, and transmitting a signal from one side of the membrane to the other to initiate a change in cell activity. GO:1990726 Lsm1-7-Pat1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990726 IntAct:EBI-16419327 A conserved, heteroheptameric, cytoplasmic protein complex composed of Lsm1, Lsm2, Lsm3, Lsm4, Lsm5, Lsm6, Lsm7, and Pat1, or orthologs thereof, that shows a strong binding preference for oligoadenylated RNAs over polyadenylated RNAs. May bind further associated proteins. Facilitates the deadenylation-dependent decapping of mRNA in the P-body thereby regulating mRNA decay and subsequent degradation by the 5' to 3' pathway. GO:1990727 tubulin folding cofactor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990727 A multimeric protein complex involved in tubulin alpha-beta-subunit folding assembly consisting of beta-tubulin-TFC-D, alpha-tubulin-TFC-E and TFC-C, through which tubulin subunit association and dimer release occur. GO:1990728 mitotic spindle assembly checkpoint MAD1-MAD2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990728 IntAct:EBI-10705307|IntAct:EBI-10691260 MAD1-MAD2 complex A protein complex involved in the assembly of the mitotic checkpoint complex that in turn inhibits the anaphase promoting complex/cyclosome (APC/C). The MAD1 dimer recruits the open form of MAD2 (O-MAD2) turning it into the closed form (C-MAD2) upon binding. C-MAD2 inhibits CDC20, a member of the APC/C, upon release from the MAD1-MAD2 complex. GO:1990721 obsolete prostatic acid phosphatase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990721 IntAct:EBI-10758292|IntAct:EBI-10758257 PAP complex|ACPP homodimer complex|prostatic acid phosphatase complex OBSOLETE. A protein complex that is capable of dephosphorylation of alky, aryl and acyl orthophosphate monoesters and phosphorylated proteins. Optimal activity in acidic environment (pH 4-6). In mammals it consists of a homodimer of ACPP. PO:0009012 plant structure development stage biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009012 plant growth and development stage (exact)|etapa de desarrollo de estructura vegetal (Spanish, exact)|Arabidopsis growth (related) A stage in the life of a plant structure (PO:0009011) during which the plant structure undergoes developmental processes. PO:0009013 portion of meristem tissue biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009013 分裂組織 (Japanese, exact)|meristema (Spanish, exact)|meristematic tissue (exact)|meristem (exact) A portion of plant tissue (PO:0009007) in which plant cells (PO:0009002) have retained their embryonic characteristics, or have reverted to them secondarily, and that divide to produce new cells that can undergo differentiation to form mature tissues, i.e. they have a capacity for morphogenesis and growth. GO:1990722 DAPK1-calmodulin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990722 IntAct:EBI-10758292|IntAct:EBI-10758257 death-associated protein kinase 1 - calmodulin complex A serine/threonine protein kinase complex involved in cell survival, apoptosis and autophagic cell death pathways. DAPK1 is activated by the dephosphorylation of a n-terminal serine and calcium-calmodulin binding. GO:1990723 cytoplasmic periphery of the nuclear pore complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990723 Cytoplasm situated in close proximity to a nuclear pore complex. GO:1990724 galectin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990724 IntAct:EBI-10705984|IntAct:EBI-10706026|IntAct:EBI-10705946|IntAct:EBI-10705755 galectin-2 complex|galectin-1 complex A homodimeric protein complex that is capable of binding a range of carbohydrates and is involved in anti-inflammatory and pro-apoptotic processes. PO:0009015 portion of vascular tissue biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009015 維管束細胞の一部 (Japanese, exact)|vascular tissue (exact)|porción de tejido vascular (Spanish, exact)|vascular system (related) A portion of plant tissue (PO:0009007) that has as part one or more tracheary elements (PO:0000290) or sieve elements (PO:0025406). CHEBI:76504 (2E,14Z,17Z,20Z,23Z,26Z,29Z)-dotriacontaheptaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76504 CHEBI:76505 (3R,16Z,19Z,22Z,25Z,28Z,31Z)-3-hydroxytetratriacontahexaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76505 GO:1990730 VCP-NSFL1C complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990730 p97-p47 complex A protein complex between the ATPase VCP (p97) and its cofactor p47 (NSFL1C). In human, the protein complex consists of one homotrimer of NSFL1C/p47 per homohexamer of VCP/p97. CHEBI:76502 (3R,14Z,17Z,20Z,23Z,26Z,29Z)-3-hydroxydotriacontahexaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76502 GO:1990731 UV-damage excision repair, DNA incision biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990731 alternative excision repair, DNA incision|nucleic acid cleavage involved in UV-damage excision repair|UVDE-dependent excision repair, DNA incision|DNA incision involved in UVDE-dependent excision repair|DNA incision involved in UV-damaged DNA endonuclease-dependent excision repair|DNA incision involved in UVER|DNA incision involved in AER|DNA incision involved in alternative excision repair|DNA incision involved in UV-damage excision repair|UV-damaged DNA endonuclease-dependent excision repair, DNA incision A process that results in the endonucleolytic cleavage of the damaged strand of DNA immediately 5' of a UV-induced damage site, and is the first part of a DNA repair process that acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs). CHEBI:76503 monobutyrin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76503 UBERON:0010160 lumen of lymphatic vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010160 lymphatic vessel lumen|lumen of lymphatic duct An anatomical cavity that surrounded_by a lymphatic vessel. CHEBI:76508 (3R,11Z)-3-hydroxyicosenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76508 UBERON:0010161 lumen of blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010161 blood vessel lumen An anatomical cavity that surrounded_by a blood vessel. CHEBI:76509 (2E,11Z)-icosadienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76509 CHEBI:76506 (2E,16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontaheptaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76506 CHEBI:76507 marine metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76507 UBERON:0010164 collection of hairs biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010164 set of hairs|pili|hairs set|hairs An anatomical cluster that composed_primarily_of a strand of hair. UBERON:0010165 collection of hair on face biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010165 set of facial hairs|facial hairs set|facial hair A collection of hairs that is part of a face. UBERON:0010162 post-anal tail tip biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010162 end of tail|tail tip The distal end of the tail GO:1990736 regulation of vascular associated smooth muscle cell membrane depolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990736 regulation of vascular smooth muscle cell membrane depolarization Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in a vascular smooth muscle cell. PO:0009005 root biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009005 raíz (Spanish, exact)|radices (exact, plural)|radix (exact)|climbing root (narrow)|根 (Japanese, exact)|aerial root (narrow) A plant axis (PO:0025004) that lacks shoot axis nodes (PO:0005004) and usually grows indeterminately. GO:1990737 response to manganese-induced endoplasmic reticulum stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990737 response to Mn-induced ER stress|manganese-induced ER stress response|response to manganese-induced ER stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of endoplasmic reticulum stress caused by a manganese stimulus. PO:0009006 shoot system biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009006 tree crown (narrow)|thallus (related)|シュート系、苗条系 (Japanese, exact)|sistema de epiblasto (epiblastema) (Spanish, exact)|shoot (related)|Poaceae crown (related)|thalli (related) A collective plant organ structure (PO:0025007) that produces shoot-borne portions of meristem tissue (PO:0009013) and the plant structures (PO:0009011) that arise from them. PO:0009007 portion of plant tissue biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009007 plant tissue (related)|portion of tissue (broad)|tissue (broad)|porción de un tejido vegetal (Spanish, exact)|植物組織の一部 (Japanese, exact) A plant structure (PO:0009011) that consists predominantly of similarly specialized plant cells (PO:0009002) of one or more types. GO:1990738 pseudouridine 5'-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990738 RHEA:10944|EC:3.1.3.96 Catalysis of the reaction: pseudouridine 5'-phosphate + H2O = pseudouridine + phosphate. PO:0009008 plant organ biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009008 organ (broad)|simple plant organ (related)|植物 器官 (Japanese, exact)|compound plant organ (related)|órgano vegetal (Spanish, exact) A multi-tissue plant structure (PO:0025496) that is a functional unit, is a proper part of a whole plant (PO:0000003), and includes portions of plant tissue (PO:0009007) of at least two different types that derive from a common developmental path. GO:1990739 granulosa cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990739 The multiplication or reproduction of granulosa cells, resulting in the expansion of the granulosa cells population. A granulosa cell is a supporting cell for the developing female gamete in the ovary of mammals. They develop from the coelomic epithelial cells of the gonadal ridge. GO:1990732 pyrenoid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990732 Wikipedia:Pyrenoid A non-membrane-bounded organelle found within the chloroplasts of algae and hornworts; responsible for carbon dioxide fixation. PO:0009001 fruit biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009001 dehiscent fruit (broad)|coenocarp (narrow)|aggregate fruit (broad)|果実 (exact, Japanese)|syncarp (narrow)|compound fruit (broad)|multiple fruit (broad)|propagule (broad)|frucht (exact, German)|fruto (exact, Spanish)|indehiscent fruit (broad)|diaspore (broad) A multi-tissue plant structure (PO:0025496) that develops from a gynoecium (PO:0009062), or a single carpel (PO:0009030), and at maturity may have as parts one or more seeds (PO:0009010). CHEBI:76500 triacontanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76500 GO:1990733 titin-telethonin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990733 IntAct:EBI-10711453 Titin-Tcap complex A protein complex formed between the N-terminus of the giant sarcomeric filament protein titin and the Z-disk ligand, telethonin. The complex is part of the Z-disk of the skeletal and cardiac sarcomere. Telethonin binding to titin might be essential for the initial assembly, stabilization and functional integrity of the titin filament, and hence important for muscle contraction relaxation in mature myofibrils. PO:0009002 plant cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009002 célula vegetal (Spanish, exact)|cell (broad)|植物細胞 (Japanese, exact) A cell which is a plant structure (PO:0009011). GO:1990734 astral microtubule anchoring at mitotic spindle pole body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990734 Any process in which an astral microtubule is maintained in a specific location in a cell by attachment to a mitotic spindle pole body. Microtubules attach to spindle pole bodies at the minus end. GO:1990735 gamma-tubulin complex localization to mitotic spindle pole body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990735 gamma-tubulin complex localisation to mitotic spindle pole body|establishment and maintenance of gamma-tubulin complex localization to mitotic spindle pole body|gamma-tubulin complex localization to mitotic SPB Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location at a mitotic spindle pole body. CHEBI:76515 (18Z,21Z,24Z,27Z,30Z,33Z)-hexatriacontahexaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76515 GO:1990740 obsolete non-selective anion channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990740 nonselective anion channel activity OBSOLETE. Enables the non-selective, energy-independent passage of anions across a lipid bilayer down a concentration gradient. GO:1990741 obsolete non-selective cation channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990741 nonselective cation channel activity OBSOLETE. Enables the non-selective, energy-independent passage of cations across a lipid bilayer down a concentration gradient. CHEBI:76513 (3R,18Z,21Z,24Z,27Z,30Z,33Z)-3-hydroxyhexatriacontahexaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76513 CHEBI:76514 (2E,18Z,21Z,24Z,27Z,30Z,33Z)-hexatriacontaheptaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76514 GO:1990742 microvesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990742 shedding vesicle|extracellular microvesicle|ectosome An extracellular vesicle released from the plasma membrane and ranging in size from about 100 nm to 1000 nm. UBERON:0010152 skin mucus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010152 epidermal mucus|skin mucous A mucous secretion that is produced by glands in the epidermis. UBERON:0010157 sphenoparietal suture biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010157 sphenoparietal suture of skull|sutura sphenoparietalis|spheno-parietal suture The Sphenoparietal suture is the cranial suture between the sphenoid bone and the parietal bone. UBERON:0010156 sphenofrontal suture biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010156 frontosphenoid suture|sphenofrontal suture of skull|sphenofrontal|sutura sphenofrontalis|spheno-frontal suture The Sphenofrontal suture is the cranial suture between the sphenoid bone and the frontal bone. GO:1990747 pancreatic trypsinogen secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990747 pancreatic trypsinogen release The regulated release of trypsinogen from the cells of the exocrine pancreas. GO:1990748 cellular detoxification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990748 Any process carried out at the cellular level that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance. GO:1990749 polynucleotide adenylyltransferase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990749 Increases the activity of the enzyme polynucleotide adenylyltransferase. GO:1990743 protein sialylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990743 A protein modification process that results in the addition of a sialic acid unit to the end of an oligosaccharide chain in a glycoprotein. CHEBI:76511 (3R,13Z)-3-hydroxydocosenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76511 GO:1990744 primary miRNA methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990744 The posttranscriptional addition of methyl groups to specific residues in an primary miRNA molecule. GO:1990745 EARP complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990745 A quatrefoil tethering complex required for endocytic recycling. GO:1990746 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990746 GO:0098565 lumenal side of endosome membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098565 internal leaflet of endosome membrane|internal side of endosome membrane The side (leaflet) of the endosome membrane that faces the lumen. GO:0001653 peptide receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001653 exogenous peptide receptor activity|endogenous peptide receptor activity Combining with an extracellular or intracellular peptide to initiate a change in cell activity. GO:0001654 eye development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001654 Wikipedia:Eye_development The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight. GO:0098566 transport vesicle lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098566 The volume enclosed within the membrane of a transport vesicle. GO:0001655 urogenital system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001655 The process whose specific outcome is the progression of the urogenital system over time, from its formation to the mature structure. GO:0098563 intrinsic component of synaptic vesicle membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098563 The component of the synaptic vesicle membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0001656 metanephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001656 The process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine. GO:0098564 trans-Golgi network transport vesicle lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098564 The volume enclosed within the membrane of a trans-Golgi network transport vesicle. GO:0098561 methyl accepting chemotaxis protein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098561 A transmembrane protein complex that consists of multiple methyl-accepting chemoreceptor protein subunits, a histidine kinase and a connector protein and which functions in the regulation of flagellar rotary motor activity in response to an external chemical stimulus. GO:0001650 fibrillar center biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001650 fibrillar centre A structure found most metazoan nucleoli, but not usually found in lower eukaryotes; surrounded by the dense fibrillar component; the zone of transcription from multiple copies of the pre-rRNA genes is in the border region between these two structures. GO:0098562 cytoplasmic side of membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098562 The side of a membrane that faces the cytoplasm. CHEBI:52557 tetracyclic diterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52557 GO:0001651 dense fibrillar component biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001651 NIF_Subcellular:sao1841764412 pars fibrosa A structure found in the nucleolus, which contains newly synthesized preribosomal RNA (pre-rRNA) and a collection of proteins. GO:0001652 granular component biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001652 NIF_Subcellular:sao1217793903 pars granulosa A structure found in the nucleolus, which contains nearly completed preribosomal particles destined for the cytoplasm. GO:0098560 cytoplasmic side of late endosome membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098560 external leaflet of late endosome membrane|external side of late endosome membrane The side (leaflet) of the late endosome membrane that faces the cytoplasm. CHEBI:27595 11-epi-prostaglandin F2alpha biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27595 GO:1902137 (-)-secoisolariciresinol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902137 (-)-secoisolariciresinol breakdown|(-)-secoisolariciresinol catabolism|(-)-secoisolariciresinol degradation The chemical reactions and pathways resulting in the breakdown of (-)-secoisolariciresinol. GO:1902138 (-)-secoisolariciresinol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902138 (-)-secoisolariciresinol anabolism|(-)-secoisolariciresinol synthesis|(-)-secoisolariciresinol formation|(-)-secoisolariciresinol biosynthesis The chemical reactions and pathways resulting in the formation of (-)-secoisolariciresinol. GO:1902135 (+)-secoisolariciresinol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902135 (+)-secoisolariciresinol anabolism|(+)-secoisolariciresinol synthesis|(+)-secoisolariciresinol formation|(+)-secoisolariciresinol biosynthesis The chemical reactions and pathways resulting in the formation of (+)-secoisolariciresinol. CHEBI:27592 ectoine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27592 GO:1902136 (-)-secoisolariciresinol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902136 (-)-secoisolariciresinol metabolism The chemical reactions and pathways involving (-)-secoisolariciresinol. GO:1902133 (+)-secoisolariciresinol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902133 (+)-secoisolariciresinol metabolism The chemical reactions and pathways involving (+)-secoisolariciresinol. GO:1902134 (+)-secoisolariciresinol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902134 (+)-secoisolariciresinol breakdown|(+)-secoisolariciresinol catabolism|(+)-secoisolariciresinol degradation The chemical reactions and pathways resulting in the breakdown of (+)-secoisolariciresinol. CHEBI:27594 carbon atom biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27594 GO:1902140 response to inositol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902140 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inositol stimulus. GO:1902141 cellular response to inositol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902141 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inositol stimulus. GO:0001657 ureteric bud development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001657 The process whose specific outcome is the progression of the ureteric bud over time, from its formation to the mature structure. GO:0098569 internal side of mycolate outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098569 The side of the mycolate outer membrane that faces the cell wall peptidoglycan. It is rich in long-chain mycolic acids (hydroxylated branched-chain fatty acids) that are covalently linked to the cell wall peptidoglycan via an arabinogalactan network. GO:0001658 branching involved in ureteric bud morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001658 ureteric bud branching The process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules. GO:0098567 periplasmic side of plasma membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098567 The side (leaflet) of a plasma membrane that faces the periplasm, and all proteins embedded in it or attached to its surface. GO:0001659 temperature homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001659 Wikipedia:Thermoregulation thermoregulation A homeostatic process in which an organism modulates its internal body temperature. GO:0098568 external side of mycolate outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098568 The side (leaflet) of the mycolate outer membrane that faces the environment and any proteins embedded in it or loosely bound to its surface. GO:0001664 G protein-coupled receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001664 Reactome:R-HSA-500717 G protein coupled receptor binding|G-protein coupled receptor binding|G-protein-coupled receptor ligand|G protein coupled receptor ligand Interacting selectively and non-covalently with a G protein-coupled receptor. GO:0098576 lumenal side of membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098576 Any side (leaflet) of a membrane that faces the lumen of an organelle. GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001665 EC:2.4.99.3|Reactome:R-HSA-4084980|RHEA:11136|MetaCyc:2.4.99.3-RXN|Reactome:R-HSA-9603991 GalNAc alpha-2,6-sialyltransferase I activity|CMP-N-acetylneuraminate:glycano-1,3-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein alpha-2,6-N-acetylneuraminyltransferase activity Catalysis of the reaction: CMP-N-acetylneuraminate + glycano-(1->3)-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein = CMP + glycano-[(2->6)-alpha-N-acetylneuraminyl]-(N-acetyl-D-galactosaminyl)-glycoprotein. GO:0098577 inactive sex chromosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098577 inactivated sex chromosome A sex chromosome that has been inactivated. GO:0001666 response to hypoxia biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001666 response to intermittent hypoxia|response to lowered oxygen tension|response to hypoxic stress|response to sustained hypoxia Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. GO:0098574 cytoplasmic side of lysosomal membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098574 external leaflet of lysosomal membrane|external side of lysosomal membrane The side (leaflet) of the lysosomal membrane that faces the cytoplasm. GO:0001667 ameboidal-type cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001667 amoeboidal cell migration|ameboid cell migration|amoeboid cell migration Cell migration that is accomplished by extension and retraction of a pseudopodium. GO:0098575 lumenal side of lysosomal membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098575 internal side of lysosomal membrane|internal leaflet of lysosomal membrane The side (leaflet) of the lysosomal membrane that faces the lumen. GO:0098572 stromal side of plastid thylakoid membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098572 The side (leaflet) of the plastid thylakoid membrane that faces the stroma, and any proteins embedded in it or loosely bound to its surface. GO:0001660 fever generation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001660 Wikipedia:Fever pyrexia The heat generation process that results in a rise in body temperature above the normal, often as a response to infection. GO:0098573 intrinsic component of mitochondrial membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098573 intrinsic to mitochondrial membrane The component of the mitochondrial membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0001661 conditioned taste aversion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001661 Wikipedia:Conditioned_taste_aversion|Wikipedia:Taste_aversion A conditioned aversion to a specific chemical compound as a result of that compound being coupled with a noxious stimulus. GO:0001662 behavioral fear response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001662 behavioural fear response An acute behavioral change resulting from a perceived external threat. GO:0098570 stromal side of plastid inner membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098570 The side (leaflet) of the plastid inner membrane that faces the stroma, and any proteins embedded in it or loosely bound to its surface. GO:0001663 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001663 GO:0098571 lumenal side of plastid thylakoid membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098571 The side (leaflet) of the plastid thylakoid membrane that faces the lumen, and any proteins embedded in it or loosely bound to its surface. GO:1902148 positive regulation of response to cytokinesis checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902148 upregulation of cytokinesis checkpoint effector process|up-regulation of response to signal involved in cytokinesis checkpoint|upregulation of response to cytokinesis checkpoint signaling|up regulation of cytokinesis checkpoint effector process|positive regulation of cytokinesis checkpoint effector process|upregulation of response to signal involved in cytokinesis checkpoint|activation of response to cytokinesis checkpoint signaling|up-regulation of response to cytokinesis checkpoint signaling|activation of cytokinesis checkpoint effector process|up-regulation of cytokinesis checkpoint effector process|up regulation of response to signal involved in cytokinesis checkpoint|positive regulation of response to signal involved in cytokinesis checkpoint|up regulation of response to cytokinesis checkpoint signaling|activation of response to signal involved in cytokinesis checkpoint Any process that activates or increases the frequency, rate or extent of response to cytokinesis checkpoint signaling. GO:1902149 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902149 GO:1902146 positive regulation of response to cell cycle checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902146 upregulation of response to signal involved in G1/S transition checkpoint|activation of cell cycle checkpoint effector process|up-regulation of response to G1/S transition checkpoint signaling|activation of G1/S transition checkpoint effector process|upregulation of response to signal involved in G2/M transition checkpoint|up-regulation of G2/M transition checkpoint effector process|positive regulation of cell cycle checkpoint effector process|up-regulation of response to G2/M transition checkpoint signaling|up regulation of response to cell cycle checkpoint signaling|activation of response to G1/S transition checkpoint signaling|up regulation of cell cycle checkpoint effector process|activation of response to cell cycle checkpoint signaling|upregulation of response to signal involved in cell cycle checkpoint|up regulation of response to signal involved in G1/S transition checkpoint|up-regulation of G1/S transition checkpoint effector process|activation of response to G2/M transition checkpoint signaling|positive regulation of response to signal involved in G1/S transition checkpoint|positive regulation of response to G1/S transition checkpoint signaling|upregulation of G2/M transition checkpoint effector process|up regulation of response to G1/S transition checkpoint signaling|up regulation of response to signal involved in G2/M transition checkpoint|positive regulation of response to signal involved in G2/M transition checkpoint|activation of response to signal involved in G1/S transition checkpoint|positive regulation of response to G2/M transition checkpoint signaling|upregulation of cell cycle checkpoint effector process|up-regulation of response to signal involved in cell cycle checkpoint|upregulation of G1/S transition checkpoint effector process|up regulation of response to G2/M transition checkpoint signaling|up-regulation of response to cell cycle checkpoint signaling|activation of response to signal involved in G2/M transition checkpoint|up-regulation of response to signal involved in G1/S transition checkpoint|upregulation of response to G1/S transition checkpoint signaling|up regulation of G2/M transition checkpoint effector process|activation of response to signal involved in cell cycle checkpoint|positive regulation of G2/M transition checkpoint effector process|up-regulation of cell cycle checkpoint effector process|up-regulation of response to signal involved in G2/M transition checkpoint|positive regulation of response to signal involved in cell cycle checkpoint|up regulation of G1/S transition checkpoint effector process|upregulation of response to cell cycle checkpoint signaling|upregulation of response to G2/M transition checkpoint signaling|activation of G2/M transition checkpoint effector process|up regulation of response to signal involved in cell cycle checkpoint|positive regulation of G1/S transition checkpoint effector process Any process that activates or increases the frequency, rate or extent of response to cell cycle checkpoint signaling. GO:1902147 regulation of response to cytokinesis checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902147 regulation of cytokinesis checkpoint effector process|regulation of response to signal involved in cytokinesis checkpoint Any process that modulates the frequency, rate or extent of response to cytokinesis checkpoint signaling. GO:1902145 regulation of response to cell cycle checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902145 regulation of response to signal involved in cell cycle checkpoint|regulation of response to signal involved in G1/S transition checkpoint|regulation of response to signal involved in G2/M transition checkpoint|regulation of cell cycle checkpoint effector process|regulation of response to G1/S transition checkpoint signaling|regulation of G2/M transition checkpoint effector process|regulation of G1/S transition checkpoint effector process|regulation of response to G2/M transition checkpoint signaling Any process that modulates the frequency, rate or extent of response to cell cycle checkpoint signaling. GO:1902153 regulation of response to DNA damage checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902153 regulation of response to signal involved in DNA damage checkpoint|regulation of DNA damage checkpoint effector process Any process that modulates the frequency, rate or extent of response to DNA damage checkpoint signaling. GO:1902154 positive regulation of response to DNA damage checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902154 positive regulation of DNA damage checkpoint effector process|up regulation of response to DNA damage checkpoint signaling|activation of response to DNA damage checkpoint signaling|up regulation of DNA damage checkpoint effector process|upregulation of response to signal involved in DNA damage checkpoint|up-regulation of response to signal involved in DNA damage checkpoint|upregulation of DNA damage checkpoint effector process|up-regulation of response to DNA damage checkpoint signaling|activation of response to signal involved in DNA damage checkpoint|up-regulation of DNA damage checkpoint effector process|upregulation of response to DNA damage checkpoint signaling|positive regulation of response to signal involved in DNA damage checkpoint|up regulation of response to signal involved in DNA damage checkpoint|activation of DNA damage checkpoint effector process Any process that activates or increases the frequency, rate or extent of response to DNA damage checkpoint signaling. GO:1902151 regulation of response to DNA integrity checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902151 regulation of DNA integrity checkpoint effector process|regulation of response to signal involved in DNA integrity checkpoint Any process that modulates the frequency, rate or extent of response to DNA integrity checkpoint signaling. GO:1902152 positive regulation of response to DNA integrity checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902152 upregulation of response to signal involved in DNA integrity checkpoint|up-regulation of response to DNA integrity checkpoint signaling|activation of response to DNA integrity checkpoint signaling|up regulation of DNA integrity checkpoint effector process|positive regulation of DNA integrity checkpoint effector process|up regulation of response to signal involved in DNA integrity checkpoint|activation of DNA integrity checkpoint effector process|positive regulation of response to signal involved in DNA integrity checkpoint|up regulation of response to DNA integrity checkpoint signaling|up-regulation of DNA integrity checkpoint effector process|activation of response to signal involved in DNA integrity checkpoint|up-regulation of response to signal involved in DNA integrity checkpoint|upregulation of response to DNA integrity checkpoint signaling|upregulation of DNA integrity checkpoint effector process Any process that activates or increases the frequency, rate or extent of response to DNA integrity checkpoint signaling. GO:1902150 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902150 GO:0001668 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001668 GO:0001669 acrosomal vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001669 Wikipedia:Acrosome acrosomal granule|acrosome A structure in the head of a spermatozoon that contains acid hydrolases, and is concerned with the breakdown of the outer membrane of the ovum during fertilization. It lies just beneath the plasma membrane and is derived from the lysosome. GO:0098578 condensed chromatin of inactivated sex chromosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098578 A condensed form of chromatin that is associated with an inactivated sex chromosome and which is responsible for its inactivation. GO:0098579 active sex chromosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098579 A sex chromosome that has not been inactivated. GO:0098543 detection of other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098543 recognition of other organism involved in symbiotic interaction|recognition of other organism during symbiotic interaction The series of events in which a stimulus from another organism is received and converted into a molecular signal. GO:0001631 cysteinyl leukotriene receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001631 CysLT receptor Combining with a cysteinyl leukotriene to initiate a change in cell activity. Cysteinyl leukotrienes are leukotrienes that contain a peptide group based on cysteine. GO:0001632 leukotriene B4 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001632 BLT receptor Combining with leukotriene B4, LTB4, to initiate a change in cell activity. Leukotriene B4 is also known as (6Z, 8E, 10E, 14Z)-(5S, 12R)-5,12-dihydroxyicosa-6,8,10,14-tetraen-1-oate. GO:0098544 maintenance of protein complex location biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098544 Any process in which a protein complex is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of protein complexes that move away. GO:0098541 cytoplasmic side of trans-Golgi network transport vesicle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098541 external side of trans-Golgi network transport vesicle membrane The side (leaflet) of the trans-Golgi network transport vesicle membrane that faces the cytoplasm. GO:0001633 obsolete secretin-like receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001633 class B G protein coupled receptor|secretin-like receptor activity|class B orphan receptor activity|class B G-protein coupled receptor|class B GPCR OBSOLETE. A G protein-coupled receptor that is structurally/functionally related to the secretin receptor. GO:0098542 defense response to other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098542 defence response to pathogen, incompatible interaction|defence response incompatible interaction|resistance response to pathogen|defense response, incompatible interaction Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism. GO:0001634 pituitary adenylate cyclase-activating polypeptide receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001634 pituitary adenylate cyclase-activating peptide receptor activity|pituitary adenylate cyclase activating polypeptide receptor|pituitary adenylate cyclase activating protein receptor activity|pituitary adenylate cyclase-activating polypeptide receptor activity|pituitary adenylyl cyclase activating protein receptor activity|PACAP receptor A G protein-coupled receptor that interacts with pituitary adenylate cyclase-activating polypeptide. GO:0098540 lumenal side of trans-Golgi network transport vesicle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098540 internal side of trans-Golgi network transport vesicle membrane The side (leaflet) of the trans-Golgi network transport vesicle membrane that faces the lumen. GO:0001630 obsolete GP40-like receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001630 GP40-like receptor activity OBSOLETE. (Was not defined before being made obsolete). CHEBI:27573 silicon atom biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27573 CHEBI:27574 N(2)-succinyl-L-ornithine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27574 GO:1902159 regulation of cyclic nucleotide-gated ion channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902159 regulation of cyclic nucleotide activated ion channel activity|regulation of cyclic nucleotide gated ion channel activity|regulation of cyclic nucleotide-activated ion channel activity Any process that modulates the frequency, rate or extent of cyclic nucleotide-gated ion channel activity. CHEBI:27576 19-hydroxyandrost-4-ene-3,17-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27576 GO:1902157 regulation of response to G2 DNA damage checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902157 regulation of response to signal involved in G2/M transition DNA damage checkpoint|regulation of G2/M transition DNA damage checkpoint effector process Any process that modulates the frequency, rate or extent of response to G2 DNA damage checkpoint signaling. GO:1902158 positive regulation of response to G2 DNA damage checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902158 up-regulation of response to signal involved in G2/M transition DNA damage checkpoint|up-regulation of G2/M transition DNA damage checkpoint effector process|upregulation of response to G2 DNA damage checkpoint signaling|activation of response to signal involved in G2/M transition DNA damage checkpoint|activation of G2/M transition DNA damage checkpoint effector process|positive regulation of response to signal involved in G2/M transition DNA damage checkpoint|positive regulation of G2/M transition DNA damage checkpoint effector process|activation of response to G2 DNA damage checkpoint signaling|up-regulation of response to G2 DNA damage checkpoint signaling|up regulation of response to signal involved in G2/M transition DNA damage checkpoint|up regulation of G2/M transition DNA damage checkpoint effector process|upregulation of response to signal involved in G2/M transition DNA damage checkpoint|upregulation of G2/M transition DNA damage checkpoint effector process|up regulation of response to G2 DNA damage checkpoint signaling Any process that activates or increases the frequency, rate or extent of response to G2 DNA damage checkpoint signaling. CHEBI:27570 histidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27570 GO:1902155 regulation of response to G1 DNA damage checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902155 regulation of response to signal involved in mitotic cell cycle G1/S transition DNA damage checkpoint|regulation of mitotic cell cycle G1/S transition DNA damage checkpoint effector process|regulation of response to mitotic cell cycle G1/S transition DNA damage checkpoint signaling Any process that modulates the frequency, rate or extent of response to G1 DNA damage checkpoint signaling. CHEBI:27571 3'-ketolactose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27571 GO:1902156 positive regulation of response to G1 DNA damage checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902156 upregulation of response to signal involved in mitotic cell cycle G1/S transition DNA damage checkpoint|upregulation of mitotic cell cycle G1/S transition DNA damage checkpoint effector process|up-regulation of response to mitotic cell cycle G1/S transition DNA damage checkpoint signaling|upregulation of response to G1 DNA damage checkpoint signaling|activation of response to mitotic cell cycle G1/S transition DNA damage checkpoint signaling|up regulation of response to signal involved in mitotic cell cycle G1/S transition DNA damage checkpoint|up regulation of mitotic cell cycle G1/S transition DNA damage checkpoint effector process|positive regulation of response to signal involved in mitotic cell cycle G1/S transition DNA damage checkpoint|positive regulation of response to mitotic cell cycle G1/S transition DNA damage checkpoint signaling|positive regulation of mitotic cell cycle G1/S transition DNA damage checkpoint effector process|up regulation of response to mitotic cell cycle G1/S transition DNA damage checkpoint signaling|activation of response to G1 DNA damage checkpoint signaling|up-regulation of response to G1 DNA damage checkpoint signaling|activation of response to signal involved in mitotic cell cycle G1/S transition DNA damage checkpoint|activation of mitotic cell cycle G1/S transition DNA damage checkpoint effector process|up-regulation of response to signal involved in mitotic cell cycle G1/S transition DNA damage checkpoint|upregulation of response to mitotic cell cycle G1/S transition DNA damage checkpoint signaling|up-regulation of mitotic cell cycle G1/S transition DNA damage checkpoint effector process|up regulation of response to G1 DNA damage checkpoint signaling Any process that activates or increases the frequency, rate or extent of response to G1 DNA damage checkpoint signaling. GO:1902164 positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902164 activation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|up-regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|upregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|up regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator Any process that activates or increases the frequency, rate or extent of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator. GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902165 regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator. GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902162 Any process that modulates the frequency, rate or extent of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator. GO:1902163 negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902163 down-regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|inhibition of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|down regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|downregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator Any process that stops, prevents or reduces the frequency, rate or extent of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator. GO:1902160 negative regulation of cyclic nucleotide-gated ion channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902160 negative regulation of cyclic nucleotide activated ion channel activity|down-regulation of cyclic nucleotide activated ion channel activity|down regulation of cyclic nucleotide-activated ion channel activity|downregulation of cyclic nucleotide-gated ion channel activity|inhibition of cyclic nucleotide-activated ion channel activity|down-regulation of cyclic nucleotide gated ion channel activity|down regulation of cyclic nucleotide-gated ion channel activity|negative regulation of cyclic nucleotide gated ion channel activity|downregulation of cyclic nucleotide activated ion channel activity|inhibition of cyclic nucleotide-gated ion channel activity|down regulation of cyclic nucleotide activated ion channel activity|downregulation of cyclic nucleotide gated ion channel activity|negative regulation of cyclic nucleotide-activated ion channel activity|down-regulation of cyclic nucleotide-activated ion channel activity|inhibition of cyclic nucleotide activated ion channel activity|down regulation of cyclic nucleotide gated ion channel activity|down-regulation of cyclic nucleotide-gated ion channel activity|inhibition of cyclic nucleotide gated ion channel activity|downregulation of cyclic nucleotide-activated ion channel activity Any process that stops, prevents or reduces the frequency, rate or extent of cyclic nucleotide-gated ion channel activity. GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902161 activation of cyclic nucleotide activated ion channel activity|up regulation of cyclic nucleotide-gated ion channel activity|up-regulation of cyclic nucleotide gated ion channel activity|upregulation of cyclic nucleotide-activated ion channel activity|positive regulation of cyclic nucleotide activated ion channel activity|up regulation of cyclic nucleotide activated ion channel activity|activation of cyclic nucleotide gated ion channel activity|upregulation of cyclic nucleotide-gated ion channel activity|positive regulation of cyclic nucleotide gated ion channel activity|up-regulation of cyclic nucleotide-activated ion channel activity|up regulation of cyclic nucleotide gated ion channel activity|upregulation of cyclic nucleotide activated ion channel activity|activation of cyclic nucleotide-activated ion channel activity|activation of cyclic nucleotide-gated ion channel activity|up-regulation of cyclic nucleotide-gated ion channel activity|positive regulation of cyclic nucleotide-activated ion channel activity|upregulation of cyclic nucleotide gated ion channel activity|up-regulation of cyclic nucleotide activated ion channel activity|up regulation of cyclic nucleotide-activated ion channel activity Any process that activates or increases the frequency, rate or extent of cyclic nucleotide-gated ion channel activity. GO:0001639 PLC activating G protein-coupled glutamate receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001639 group I metabotropic glutamate receptor activity|Group I metabotropic glutamate receptor|phospholipase C activating metabotropic glutamate receptor activity|PLC activating metabotropic glutamate receptor activity|PLC activating G-protein coupled glutamate receptor activity A G protein-coupled receptor that binds glutamate and is linked to the inositol 1,4,5-trisphosphate/calcium signaling system. GO:0098549 somatic ring canal biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098549 A stable intercellular bridge between somatic cells. Examples include the intercellular bridges between ovarian follicle cells in insects and between imaginal disc cells in insects. GO:0001635 calcitonin gene-related peptide receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001635 Wikipedia:CALCRL calcitonin gene-related polypeptide receptor activity|CGRP receptor Combining with a calcitonin gene-related polypeptide (CGRP) to initiate a change in cell activity. GO:0098547 lumenal side of Golgi membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098547 The side of the Golgi membrane that faces the lumen. GO:0098548 cytoplasmic side of Golgi membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098548 The side (leaflet) of the Golgi membrane that faces the cytoplasm. GO:0001636 obsolete corticotrophin-releasing factor gastric inhibitory peptide-like receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001636 corticotrophin-releasing factor gastric inhibitory peptide-like receptor activity OBSOLETE. (Was not defined before being made obsolete). GO:0001637 G protein-coupled chemoattractant receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001637 G-protein chemoattractant receptor activity|G protein chemoattractant receptor activity|G-protein coupled chemoattractant receptor activity Combining with a chemoattractant and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. GO:0098545 maintenance of protein complex location in cytoplasm biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098545 Any process in which a protein complex is maintained in a specific location within the cytoplasm and is prevented from moving elsewhere. GO:0098546 2',5-3',5'-cyclic GMP-AMP binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098546 c[G(2',5')pA(3',5')p] binding Interacting selectively and non-covalently with c[G(2',5')pA(2',5')p], a cyclic purine dinucleotide that consists of AMP and GMP units cyclized via 2',5' and 3',5' linkages. GO:0001638 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001638 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098554 The side (leaflet) of the plasma membrane that faces the cytoplasm. GO:0001642 group III metabotropic glutamate receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001642 A G protein-coupled receptor that is activated by L-AP-4 and inhibits adenylate cyclase activity. GO:0098555 lumenal side of rough endoplasmic reticulum membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098555 The side (leaflet) of the rough endoplasmic reticulum membrane that faces the lumen. GO:0001643 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001643 GO:0098552 side of membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098552 A cellular component consisting of one leaflet of a membrane bilayer and any proteins embedded or anchored in it or attached to its surface. GO:0001644 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001644 GO:0001645 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001645 GO:0098553 lumenal side of endoplasmic reticulum membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098553 The side (leaflet) of the plasma membrane that faces the lumen. GO:0098550 lumenal side of early endosome membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098550 internal side of early endosome membrane|internal leaflet of early endosome membrane The side (leaflet) of the early endosome membrane that faces the lumen. GO:0098551 lumenal side of late endosome membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098551 internal leaflet of late endosome membrane|internal side of late endosome membrane The side (leaflet) of the late endosome membrane that faces the lumen. GO:0001640 adenylate cyclase inhibiting G protein-coupled glutamate receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001640 adenylate cyclase inhibiting metabotropic glutamate receptor activity|adenylyl cyclase inhibiting metabotropic glutamate receptor activity Combining with glutamate and transmitting the signal across the membrane by activating the alpha-subunit of an associated heterotrimeric G-protein complex to inhibit downstream adenylate cyclase activity. GO:0001641 group II metabotropic glutamate receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001641 A G protein-coupled receptor that is activated by trans-1-aminocyclopentane-1,3-dicarboxylic acid (t-ACPD) and inhibits adenylate cyclase activity. CHEBI:27584 aldosterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27584 CHEBI:27585 selenomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27585 CHEBI:27586 beta-L-rhamnopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27586 GO:1902168 response to catechin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902168 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catechin stimulus. GO:1902169 cellular response to catechin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902169 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catechin stimulus. GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902166 down-regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|inhibition of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|inhibition of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|down-regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|down regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|downregulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|downregulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|down regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator. CHEBI:27582 16alpha-hydroxyandrost-4-ene-3,17-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27582 GO:1902167 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902167 up-regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|up-regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|activation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|upregulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|up regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|up regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|activation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|upregulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator. GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902175 regulation of intrinsic apoptotic signaling pathway in response to oxidative stress Any process that modulates the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway. GO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902176 downregulation of intrinsic apoptotic signaling pathway in response to oxidative stress|down-regulation of intrinsic apoptotic signaling pathway in response to oxidative stress|negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress|inhibition of intrinsic apoptotic signaling pathway in response to oxidative stress|down regulation of intrinsic apoptotic signaling pathway in response to oxidative stress Any process that stops, prevents or reduces the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway. GO:1902173 negative regulation of keratinocyte apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902173 down regulation of keratinocyte apoptotic process|inhibition of keratinocyte apoptosis|inhibition of keratinocyte apoptotic process|down-regulation of keratinocyte apoptosis|negative regulation of keratinocyte apoptosis|down-regulation of keratinocyte apoptotic process|downregulation of keratinocyte apoptosis|down regulation of keratinocyte apoptosis|downregulation of keratinocyte apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of keratinocyte apoptotic process. GO:1902174 positive regulation of keratinocyte apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902174 upregulation of keratinocyte apoptosis|upregulation of keratinocyte apoptotic process|up-regulation of keratinocyte apoptosis|up-regulation of keratinocyte apoptotic process|activation of keratinocyte apoptotic process|activation of keratinocyte apoptosis|positive regulation of keratinocyte apoptosis|up regulation of keratinocyte apoptosis|up regulation of keratinocyte apoptotic process Any process that activates or increases the frequency, rate or extent of keratinocyte apoptotic process. CHEBI:27590 7-hydroxyflavanone 7-O-beta-D-glucoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27590 GO:1990707 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990707 GO:1902171 regulation of tocopherol cyclase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902171 Any process that modulates the frequency, rate or extent of tocopherol cyclase activity. GO:1990708 conditioned place preference biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990708 The associative learning process by which an animal learns and remembers an association between a neutral, unchanging environment and a putatively rewarding, internal state produced by a xenobiotic or drug. GO:1902172 regulation of keratinocyte apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902172 regulation of keratinocyte apoptosis Any process that modulates the frequency, rate or extent of keratinocyte apoptotic process. GO:1990709 presynaptic active zone organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990709 presynaptic active zone organisation A process that results in the assembly, arrangement of constituent parts, or disassembly of a presynaptic active zone. GO:1902170 cellular response to reactive nitrogen species biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902170 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive nitrogen species stimulus. GO:1990703 integral component of Golgi medial cisterna membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990703 integral component of medial-Golgi cisterna membrane The component of the Golgi medial membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:1990704 integral component of Golgi trans cisterna membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990704 integral component of trans-Golgi cisterna membrane The component of the Golgi trans membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:1990705 cholangiocyte proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990705 hepatoblast proliferation The multiplication or reproduction of cholangiocytes, resulting in the expansion of the cholangiocyte population. A cholangiocyte is an epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water. GO:1990706 MAD1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990706 IntAct:EBI-10691160 MAD1 homodimer A protein complex involved in the assembly of the mitotic checkpoint complex that in turn inhibits the anaphase promoting complex/cyclosome (APC/C). GO:0098558 lumenal side of smooth endoplasmic reticulum membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098558 The side (leaflet) of the smooth endoplasmic reticulum membrane that faces the lumen. GO:0001646 cAMP receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001646 3',5'-cAMP receptor activity|adenosine 3',5'-cyclophosphate receptor activity|class E G-protein coupled receptor|cyclic AMP receptor activity|class E GPCR|3',5' cAMP receptor activity|class E G protein coupled receptor Combining with cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0001647 G protein-coupled cytokinin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001647 G protein coupled cytokinin receptor activity|cytokinin receptor activity, G-protein coupled|G-protein coupled cytokinin receptor activity Combining with cytokinin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. GO:1990700 nucleolar chromatin organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990700 nucleolar chromatin organisation|establishment or maintenance of nucleolar chromatin architecture Any process that results in the specification, formation or maintenance of the physical structure of nucleolar chromatin. GO:0098559 cytoplasmic side of early endosome membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098559 external leaflet of early endosome membrane|external side of early endosome membrane The side (leaflet) of the early endosome membrane that faces the cytoplasm. GO:1990701 integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990701 integral component of ERGIC membrane|integral component of ER-Golgi intermediate compartment membrane|integral component of endoplasmic reticulum-Golgi intermediate compartment membrane The component of the ERGIC membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098556 The side (leaflet) of the rough endoplasmic reticulum membrane that faces the cytoplasm. GO:0001648 proteinase activated receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001648 A G protein-coupled peptide receptor activity that is initiated by cleavage of the N terminus of the receptor by a serine protease, resulting in the generation of a new tethered ligand that interacts with the receptor. GO:0098557 cytoplasmic side of smooth endoplasmic reticulum membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098557 The side (leaflet) of the smooth endoplasmic reticulum membrane that faces the cytoplasm. GO:1990702 integral component of Golgi cis cisterna membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990702 integral component of cis-Golgi cisterna membrane The component of the Golgi cis membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0001649 osteoblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001649 osteoblast cell differentiation The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, a mesodermal or neural crest cell that gives rise to bone. GO:0001610 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001610 GO:0001611 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001611 GO:0001612 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001612 CHEBI:27555 prostaglandin C2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27555 CHEBI:27551 5-methylcytosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27551 GO:1902179 verruculogen metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902179 verruculogen metabolism The chemical reactions and pathways involving verruculogen. GO:1902177 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902177 up regulation of intrinsic apoptotic signaling pathway in response to oxidative stress|activation of intrinsic apoptotic signaling pathway in response to oxidative stress|positive regulation of intrinsic apoptotic signaling pathway in response to oxidative stress|up-regulation of intrinsic apoptotic signaling pathway in response to oxidative stress|upregulation of intrinsic apoptotic signaling pathway in response to oxidative stress Any process that activates or increases the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway. GO:1902178 fibroblast growth factor receptor apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902178 fibroblast growth factor receptor signalling pathway involved in programmed cell death by apoptosis|FGFR signaling pathway involved in programmed cell death by apoptosis|FGF receptor signalling pathway involved in programmed cell death by apoptosis|FGF receptor signaling pathway involved in apoptotic process|fibroblast growth factor receptor signaling pathway involved in apoptotic programmed cell death|FGF receptor signaling pathway involved in apoptotic programmed cell death|fibroblast growth factor receptor signalling pathway involved in type I programmed cell death|fibroblast growth factor receptor signalling pathway involved in signaling (initiator) caspase activity|FGFR signaling pathway involved in type I programmed cell death|FGF receptor signalling pathway involved in type I programmed cell death|fibroblast growth factor receptor signaling pathway involved in apoptotic program|FGFR signaling pathway involved in apoptosis|FGFR signaling pathway involved in signaling (initiator) caspase activity|FGF receptor signalling pathway involved in signaling (initiator) caspase activity|FGF receptor signalling pathway involved in apoptosis|FGF receptor signaling pathway involved in apoptotic program|fibroblast growth factor receptor signalling pathway involved in apoptosis|fibroblast growth factor receptor signalling pathway involved in apoptotic cell death|FGFR signaling pathway involved in apoptotic cell death|FGF receptor signalling pathway involved in apoptotic cell death|FGF receptor signaling pathway involved in programmed cell death by apoptosis|FGF receptor signalling pathway involved in apoptotic process|FGFR signaling pathway involved in apoptotic process|fibroblast growth factor receptor signaling pathway involved in programmed cell death by apoptosis|fibroblast growth factor receptor signalling pathway involved in apoptotic process|FGF receptor signalling pathway involved in apoptotic programmed cell death|FGFR signaling pathway involved in apoptotic programmed cell death|fibroblast growth factor receptor signalling pathway involved in apoptotic programmed cell death|FGF receptor signaling pathway involved in type I programmed cell death|fibroblast growth factor receptor signaling pathway involved in type I programmed cell death|FGF receptor signaling pathway involved in signaling (initiator) caspase activity|FGFR signaling pathway involved in apoptotic program|FGF receptor signalling pathway involved in apoptotic program|fibroblast growth factor receptor signaling pathway involved in signaling (initiator) caspase activity|fibroblast growth factor receptor signalling pathway involved in apoptotic program|FGF receptor signaling pathway involved in apoptotic cell death|fibroblast growth factor receptor signaling pathway involved in apoptotic cell death|fibroblast growth factor receptor signaling pathway involved in apoptosis|fibroblast growth factor receptor signaling pathway involved in apoptotic process|FGF receptor signaling pathway involved in apoptosis An apoptotic signaling pathway that starts with a ligand binding to, or being withdrawn from, a fibroblast growth factor receptor (FGFR). UBERON:0009117 indifferent gonad biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009117 gonad rudiment A gonad prior to differentiating into a definitive testis or ovary. GO:1902186 regulation of viral release from host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902186 regulation of viral shedding|regulation of viral exit|regulation of release of virus from host|regulation of viral release Any process that modulates the frequency, rate or extent of viral release from host cell. GO:1902187 negative regulation of viral release from host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902187 down regulation of viral shedding|inhibition of release of virus from host|down-regulation of viral release|negative regulation of viral release|down-regulation of viral exit|negative regulation of viral exit|inhibition of viral shedding|down-regulation of viral release from host cell|downregulation of viral exit|negative regulation of release of virus from host|down-regulation of release of virus from host|downregulation of viral release from host cell|inhibition of viral release|down-regulation of viral shedding|negative regulation of viral shedding|down regulation of viral exit|down regulation of viral release from host cell|inhibition of viral release from host cell|downregulation of release of virus from host|down regulation of viral release|inhibition of viral exit|downregulation of viral shedding|down regulation of release of virus from host|downregulation of viral release Any process that stops, prevents or reduces the frequency, rate or extent of viral release from host cell. GO:1902184 negative regulation of shoot apical meristem development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902184 inhibition of shoot apical meristem development|inhibition of primary shoot meristem development|negative regulation of promeristem development|down-regulation of promeristem development|inhibition of SAM development|down regulation of shoot apical meristem development|inhibition of promeristem development|down-regulation of primary shoot meristem development|negative regulation of primary shoot meristem development|downregulation of shoot apical meristem development|down regulation of SAM development|downregulation of SAM development|down regulation of promeristem development|downregulation of primary shoot meristem development|down-regulation of shoot apical meristem development|downregulation of promeristem development|down regulation of primary shoot meristem development|down-regulation of SAM development|negative regulation of SAM development Any process that stops, prevents or reduces the frequency, rate or extent of shoot apical meristem development. GO:1902185 positive regulation of shoot apical meristem development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902185 positive regulation of promeristem development|activation of SAM development|up-regulation of shoot apical meristem development|activation of promeristem development|up-regulation of SAM development|up-regulation of primary shoot meristem development|up-regulation of promeristem development|upregulation of shoot apical meristem development|activation of primary shoot meristem development|upregulation of SAM development|positive regulation of primary shoot meristem development|upregulation of promeristem development|up regulation of shoot apical meristem development|up regulation of primary shoot meristem development|activation of shoot apical meristem development|up regulation of SAM development|positive regulation of SAM development|up regulation of promeristem development|upregulation of primary shoot meristem development Any process that activates or increases the frequency, rate or extent of shoot apical meristem development. GO:1902182 shoot apical meristem development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902182 promeristem development|primary shoot meristem development|SAM development The process whose specific outcome is the progression of a shoot apical meristem over time, from its formation to the mature structure. GO:1902183 regulation of shoot apical meristem development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902183 regulation of SAM development|regulation of promeristem development|regulation of primary shoot meristem development Any process that modulates the frequency, rate or extent of shoot apical meristem development. GO:1902180 verruculogen catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902180 verruculogen breakdown|verruculogen degradation|verruculogen catabolism The chemical reactions and pathways resulting in the breakdown of verruculogen. GO:1902181 verruculogen biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902181 verruculogen biosynthesis|verruculogen anabolism|verruculogen synthesis|verruculogen formation The chemical reactions and pathways resulting in the formation of verruculogen. GO:0001617 obsolete growth hormone secretagogue-like receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001617 growth hormone secretagogue-like receptor activity OBSOLETE. (Was not defined before being made obsolete). OBA:0007000 DNA stability biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0007000 macromolecular stability of DNA The macromolecular stability of a DNA. GO:0001618 virus receptor activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0001618 viral receptor activity Combining with a virus component and mediating entry of the virus into the cell. GO:0001619 obsolete lysosphingolipid and lysophosphatidic acid receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001619 lysosphingolipid and lysophosphatidic acid receptor activity OBSOLETE. Combining with lysosphingolipid or lysophosphatidic acid to initiate a change in cell activity. GO:0001613 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001613 GO:0001614 purinergic nucleotide receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001614 purinoreceptor|P2 receptor|purinergic receptor activity|purinoceptor Combining with a purine nucleotide and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. UBERON:0009114 cervical thymus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009114 A mature thymus that is entirely part of the cervical region. UBERON:0009115 thoracic thymus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009115 A mature thymus that is entirely part of thoracic region. GO:0001615 obsolete thyrotropin releasing hormone and secretagogue-like receptors activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001615 thyrotropin releasing hormone and secretagogue-like receptors activity OBSOLETE. (Was not defined before being made obsolete). GO:0001616 growth hormone secretagogue receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001616 ghrelin receptor activity Combining with ghrelin to initiate a change in cell activity. GO:0001620 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001620 GO:0001621 G protein-coupled ADP receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001621 K101 receptor|ADP receptor activity|ADP-activated adenosine receptor activity|platelet ADP receptor activity|ADP-activated nucleotide receptor activity Combining with ADP and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. GO:0001622 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001622 GO:0001623 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001623 CHEBI:52507 haloindole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52507 CHEBI:52500 cobyrinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52500 CHEBI:52501 2-hydroxycarbonyl compound biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52501 CHEBI:27568 selenium atom biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27568 CHEBI:27569 arabinogalactan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27569 CHEBI:27562 20-hydroxy-20-oxoleukotriene B4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27562 CHEBI:27563 arsenic atom biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27563 CHEBI:27565 4-aminosalicylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27565 CHEBI:52508 chloroindole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52508 GO:1902188 positive regulation of viral release from host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902188 upregulation of release of virus from host|up-regulation of viral exit|up regulation of viral release|up-regulation of viral release from host cell|positive regulation of viral release|activation of viral release from host cell|upregulation of viral shedding|activation of viral exit|activation of viral release|up-regulation of release of virus from host|positive regulation of viral exit|up-regulation of viral shedding|up-regulation of viral release|up regulation of viral exit|up regulation of viral release from host cell|activation of release of virus from host|activation of viral shedding|positive regulation of release of virus from host|upregulation of viral release|up regulation of release of virus from host|positive regulation of viral shedding|upregulation of viral exit|upregulation of viral release from host cell|up regulation of viral shedding Any process that activates or increases the frequency, rate or extent of viral release from host cell. CHEBI:27560 boron atom biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27560 CHEBI:27561 oxirane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27561 GO:1902189 2-methylbutanoyl-CoA(4-) metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902189 2-methylbutanoyl-CoA(4-) metabolism The chemical reactions and pathways involving 2-methylbutanoyl-CoA(4-). GO:1902197 isovaleryl-CoA(4-) biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902197 isovaleryl-CoA(4-) anabolism|isovaleryl-CoA(4-) biosynthesis|isovaleryl-CoA(4-) synthesis|isovaleryl-CoA(4-) formation The chemical reactions and pathways resulting in the formation of isovaleryl-CoA(4-). GO:1902198 3-methylbut-2-enoyl-CoA(4-) metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902198 3-methylbut-2-enoyl-CoA(4-) metabolism The chemical reactions and pathways involving 3-methylbut-2-enoyl-CoA(4-). GO:1902195 isovaleryl-CoA(4-) metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902195 isovaleryl-CoA(4-) metabolism The chemical reactions and pathways involving isovaleryl-CoA(4-). GO:1902196 isovaleryl-CoA(4-) catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902196 isovaleryl-CoA(4-) catabolism|isovaleryl-CoA(4-) degradation|isovaleryl-CoA(4-) breakdown The chemical reactions and pathways resulting in the breakdown of isovaleryl-CoA(4-). GO:1902193 2-methylbut-2-enoyl-CoA(4-) catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902193 2-methylbut-2-enoyl-CoA(4-) catabolism|2-methylbut-2-enoyl-CoA(4-) degradation|2-methylbut-2-enoyl-CoA(4-) breakdown The chemical reactions and pathways resulting in the breakdown of 2-methylbut-2-enoyl-CoA(4-). GO:1902194 2-methylbut-2-enoyl-CoA(4-) biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902194 2-methylbut-2-enoyl-CoA(4-) biosynthesis|2-methylbut-2-enoyl-CoA(4-) anabolism|2-methylbut-2-enoyl-CoA(4-) synthesis|2-methylbut-2-enoyl-CoA(4-) formation The chemical reactions and pathways resulting in the formation of 2-methylbut-2-enoyl-CoA(4-). GO:1902191 2-methylbutanoyl-CoA(4-) biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902191 2-methylbutanoyl-CoA(4-) anabolism|2-methylbutanoyl-CoA(4-) synthesis|2-methylbutanoyl-CoA(4-) formation|2-methylbutanoyl-CoA(4-) biosynthesis The chemical reactions and pathways resulting in the formation of 2-methylbutanoyl-CoA(4-). GO:1902192 2-methylbut-2-enoyl-CoA(4-) metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902192 2-methylbut-2-enoyl-CoA(4-) metabolism The chemical reactions and pathways involving 2-methylbut-2-enoyl-CoA(4-). GO:0001628 obsolete gastropyloric receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001628 gastropyloric receptor activity|GPR receptor OBSOLETE. (Was not defined before being made obsolete). GO:1902190 2-methylbutanoyl-CoA(4-) catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902190 2-methylbutanoyl-CoA(4-) degradation|2-methylbutanoyl-CoA(4-) breakdown|2-methylbutanoyl-CoA(4-) catabolism The chemical reactions and pathways resulting in the breakdown of 2-methylbutanoyl-CoA(4-). GO:0001629 obsolete G-protein receptor 45-like receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001629 G protein receptor 45-like receptor activity|GPR45-like receptor|G-protein receptor 45-like receptor activity OBSOLETE. (Was not defined before being made obsolete). GO:0001624 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001624 GO:0001625 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001625 GO:0001626 nociceptin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001626 OFQ receptor activity|ORPH receptor|X-opioid receptor activity|nociceptin/orphanin-FQ receptor activity|orphanin-FQ receptor activity Combining with the peptide nociceptin, and transmitting the signal across the membrane by activating an associated G-protein. GO:0001627 obsolete leucine-rich G-protein receptor-like receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001627 leucine-rich G-protein receptor-like receptor activity|leucine-rich G protein receptor-like receptor activity|LGR-like receptor OBSOLETE. (Was not defined before being made obsolete). CHEBI:27537 trans-oct-2-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27537 GO:0098587 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0098587 GO:0098588 bounding membrane of organelle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098588 The lipid bilayer that forms the outer-most layer of an organelle. GO:0098585 host cell synaptic vesicle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098585 The lipid bilayer surrounding a host synaptic vesicle. CHEBI:27539 isatin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27539 GO:0098586 cellular response to virus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098586 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus. CHEBI:27533 beta-zeacarotene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27533 GO:0098583 learned vocalization behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098583 A vocalization behavior that is the result of learning. GO:0098584 host cell synaptic vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098584 A secretory organelle of a host cell, some 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane. GO:0098581 detection of external biotic stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098581 detection of exogenous biotic stimulus The series of events in which an external biotic stimulus is detected and converted into a molecular signal. An external biotic stimulus is defined as one caused or produced by a living organism other than the one being stimulated. CHEBI:27535 alpha-D-mannoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27535 GO:0098582 innate vocalization behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098582 A vocalisation behavior that is innate, i.e. that does not need to be learned in order to occur. GO:0098580 obsolete chromatin of active sex chromosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098580 OBSOLETE. Chromatin that is part of an active sex chromosome. CHEBI:27530 4-hydroxy-2-oxohexanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27530 CHEBI:27532 L-cysteine thioether biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27532 GO:1902199 3-methylbut-2-enoyl-CoA(4-) catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902199 3-methylbut-2-enoyl-CoA(4-) breakdown|3-methylbut-2-enoyl-CoA(4-) catabolism|3-methylbut-2-enoyl-CoA(4-) degradation The chemical reactions and pathways resulting in the breakdown of 3-methylbut-2-enoyl-CoA(4-). GO:0098589 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0098589 GO:0098598 learned vocalization behavior or vocal learning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098598 Vocalisation behavior that is the result of learning, or the process by which new vocalizations are learned. GO:0098599 palmitoyl hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098599 Reactome:R-HSA-5690046|Reactome:R-HSA-9027670 Catalysis of a hydrolase reaction that removes a palmitoyl moiety from some substrate. GO:0098596 imitative learning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098596 Wikipedia:Imitative_learning|Wikipedia:Observational_learning#Observational_learning_compared_to_imitation Learning in which new behaviors are acquired through imitation. GO:0001600 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001600 GO:0098597 observational learning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098597 Wikipedia:Observational_learning Learning that occurs through observing the behavior of others. GO:0001601 peptide YY receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001601 Combining with gut peptide YY to initiate a change in cell activity. GO:0098594 mucin granule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098594 A secretory granule that contains mucin. CHEBI:27544 3,5-dibromo-4-hydroxybenzoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27544 CHEBI:27545 2,5-dichlorohydroquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27545 GO:0098595 perivitelline space biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098595 The space between the membrane of an oocyte and a surrounding membranous structure (zona pellucida or perivitelline membrane). GO:0098592 cytoplasmic side of apical plasma membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098592 The side (leaflet) of the apical region of the plasma membrane that faces the cytoplasm. CHEBI:27547 zeaxanthin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27547 GO:0098593 goblet cell theca biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098593 A cup shaped specialization of the cytoskeleton that forms a thin layer located just below the apical mass of mature mucin secretory granules in the cytoplasm of goblet cells of the intestinal epithelium. It consists of an orderly network of intermediate filaments and microtubules. Microtubules are arranged vertically, like barrel staves, along the inner aspect of the theta. Intermediate filaments form two networks: an inner, basketlike network and an outer series of circumferential bundles resembling the hoops of a barrel. GO:0098590 plasma membrane region biolink:CellularComponent go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0098590 region of plasma membrane A membrane that is a (regional) part of the plasma membrane. CHEBI:27540 hexanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27540 CHEBI:27541 3',5'-cyclic IMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27541 GO:0098591 external side of apical plasma membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098591 The leaflet the apical region of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface. CHEBI:27543 9H-carbazole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27543 GO:0001606 obsolete GPR37/endothelin B-like receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001606 GPR37/endothelin B-like receptor activity OBSOLETE. (Was not defined before being made obsolete). GO:0001607 neuromedin U receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001607 NMUR activity Combining with neuromedin U to initiate a change in cell activity. GO:0001608 G protein-coupled nucleotide receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001608 G-protein coupled nucleotide receptor activity|nucleotide receptor activity, G-protein coupled|nucleotide receptor activity, G protein coupled|G protein coupled nucleotide receptor activity Combining with a nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. GO:0001609 G protein-coupled adenosine receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001609 G-protein-coupled A2B adenosine receptor activity|A1 adenosine receptor activity, G protein coupled|G protein coupled A3 adenosine receptor activity|A2A adenosine receptor activity, G protein coupled|G-protein-coupled A2A adenosine receptor activity|A2B adenosine receptor activity, G protein coupled|A3 adenosine receptor activity, G protein coupled|G protein coupled A1 adenosine receptor activity|G protein coupled A2B adenosine receptor activity|G-protein-coupled A3 adenosine receptor activity|G protein coupled A2A adenosine receptor activity|G-protein-coupled A1 adenosine receptor activity|G-protein coupled adenosine receptor activity|A1 adenosine receptor activity, G-protein coupled|A2A adenosine receptor activity, G-protein coupled|A2B adenosine receptor activity, G-protein coupled|A3 adenosine receptor activity, G-protein coupled|P1 receptor|adenosine receptor activity, G-protein coupled|adenosine receptor activity, G protein coupled|adenosine nucleotide receptor|G protein coupled adenosine receptor activity Combining with adenosine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. GO:0001602 pancreatic polypeptide receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001602 Combining with pancreatic polypeptide PP to initiate a change in cell activity. GO:0001603 obsolete vasopressin-like receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001603 vasopressin-like receptor activity OBSOLETE. (Was not defined before being made obsolete). GO:0001604 urotensin II receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001604 Combining with urotensin II to initiate a change in cell activity. GO:0001605 adrenomedullin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001605 G10D receptor Combining with adrenomedullin to initiate a change in cell activity. GO:0050543 icosatetraenoic acid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050543 eicosatetraenoic acid binding Interacting selectively and non-covalently with icosatetraenoic acid, any straight-chain fatty acid with twenty carbon atoms and four double bonds per molecule. GO:0050544 arachidonic acid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050544 arachidonate binding Interacting selectively and non-covalently with arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer. GO:0050541 beta,beta-carotene-9',10'-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050541 b,b-carotene-9',10'-dioxygenase activity Catalysis of the reaction: beta-carotene + O2 = beta-apo-10'-carotenal + beta-ionone. GO:0050542 icosanoid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050542 eicosanoid binding Interacting selectively and non-covalently with icosanoids, any C20 polyunsaturated fatty acids or their derivatives, including the leukotrienes and the prostanoids. GO:0050547 vanillin synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050547 EC:4.1.2.41|RHEA:18725|KEGG_REACTION:R05773|MetaCyc:4.1.2.41-RXN 3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoyl-CoA vanillin-lyase (acetyl-CoA-forming)|3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propionyl-CoA:vanillin lyase (acetyl-CoA-forming) Catalysis of the reaction: 3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoyl-CoA = acetyl-CoA + vanillin. GO:0050548 trans-feruloyl-CoA hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050548 MetaCyc:4.2.1.101-RXN|EC:4.2.1.101|RHEA:14517 trans-feruloyl-CoA hydro-lyase activity|4-hydroxy-3-methoxyphenyl-beta-hydroxypropanoyl-CoA hydro-lyase (trans-feruloyl-CoA-forming) Catalysis of the reaction: trans-feruloyl-CoA + H2O = 4-hydroxy-3-methoxyphenyl-beta-hydroxypropionyl-CoA. GO:0050545 sulfopyruvate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050545 MetaCyc:R231-RXN|KEGG_REACTION:R05774|RHEA:20948|EC:4.1.1.79 sulfopyruvate carboxy-lyase (2-sulfoacetaldehyde-forming)|sulfopyruvate carboxy-lyase activity|sulphopyruvate decarboxylase activity Catalysis of the reaction: 3-sulfopyruvate + H(+) = CO(2) + sulfoacetaldehyde. GO:0050546 4-hydroxyphenylpyruvate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050546 EC:4.1.1.80|KEGG_REACTION:R03341|RHEA:18697|MetaCyc:4.1.1.80-RXN 4-hydroxyphenylpyruvate carboxy-lyase activity|4-hydroxyphenylpyruvate carboxy-lyase (4-hydroxyphenylacetaldehyde-forming) Catalysis of the reaction: (4-hydroxyphenyl)pyruvate + H(+) = (4-hydroxyphenyl)acetaldehyde + CO(2). GO:0050549 cyclohexyl-isocyanide hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050549 MetaCyc:4.2.1.103-RXN|KEGG_REACTION:R05771|EC:4.2.1.103|RHEA:18197|UM-BBD_reactionID:r1029 N-cyclohexylformamide hydro-lyase (cyclohexyl-isocyanide-forming)|isonitrile hydratase activity|N-cyclohexylformamide hydro-lyase activity Catalysis of the reaction: N-cyclohexylformamide + H(+) = cyclohexyl isocyanide + H(2)O. CL:0000240 stratified squamous epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000240 CL:0000243 obsolete glial cell (sensu Vertebrata) biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000243 A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Form the myelin insulation of nervous pathways, guide neuronal migration during development, and exchange metabolites with neurons. Neuroglia have high-affinity transmitter uptake systems, voltage-dependent and transmitter-gated ion channels, and can release transmitters, but their role in signaling (as in many other functions) is unclear. CL:0000244 transitional epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000244 A cell characteristically found lining hollow organs that are subject to great mechanical change due to contraction and distention; originally thought to represent a transition between stratified squamous and columnar epithelium. CHEBI:76481 (3R,23Z,26Z,29Z,32Z,35Z)-3-hydroxyoctatriacontapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76481 CL:0000247 Rohon-Beard neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000247 Rohon Beard cell|RB neuron|Rohon-Beard cell Type of neuron that is a primary mechanosensory cell, with peripheral neurites innervating the skin with free nerve endings. CHEBI:76485 (R)-3-hydroxytriacontanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76485 CHEBI:76483 (2E,23Z,26Z,29Z,32Z,35Z)-octatriacontahexaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76483 CHEBI:76484 (23Z,26Z,29Z,32Z,35Z)-octatriacontapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76484 GO:0050540 2-aminomuconate deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050540 MetaCyc:3.5.99.5-RXN|EC:3.5.99.5|RHEA:20996|KEGG_REACTION:R03887 2-aminomuconate aminohydrolase activity Catalysis of the reaction: 2-aminomuconate + H(2)O + H(+) = (Z)-5-oxohex-2-enedioate + NH(4)(+). GO:0050554 abietadiene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050554 EC:4.2.3.18|RHEA:13873|KEGG_REACTION:R06301|MetaCyc:4.2.3.18-RXN copalyl-diphosphate diphosphate-lyase (cyclizing)|(+)-copalyl-diphosphate diphosphate-lyase (cyclizing, (-)-abietadiene-forming)|abietadiene cyclase activity Catalysis of the reaction: (+)-copalyl diphosphate = (-)-abietadiene + diphosphate. GO:0050555 2-hydroxypropyl-CoM lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050555 EC:4.4.1.23|MetaCyc:4.2.99.19-RXN|RHEA:19421|UM-BBD_enzymeID:e0538 2-hydroxypropyl-CoM:2-mercaptoethanesulfonate lyase (epoxyalkane-ring-forming)|epoxyalkane:2-mercaptoethanesulfonate transferase activity|(R)-[or (S)-]2-hydroxypropyl-CoM:2-mercaptoethanesulfonate lyase (epoxyalkane-ring-forming)|epoxyalkyl:CoM transferase activity|epoxyalkane:coenzyme M transferase activity|coenzyme M-epoxyalkane ligase activity|(R)-2-hydroxypropyl-CoM 2-mercaptoethanesulfonate lyase (cyclizing; epoxyalkane-ring-forming)|epoxypropyl:CoM transferase activity|epoxypropane:coenzyme M transferase activity|epoxyalkane:CoM transferase activity|EaCoMT activity Catalysis of the reactions: (R)-2-hydroxypropyl-CoM = H-S-CoM + (R)-1,2-epoxypropane, and (S)-2-hydroxypropyl-CoM = H-S-CoM + (S)-1,2-epoxypropane. GO:0050552 (4S)-limonene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050552 EC:4.2.3.16|RHEA:12869|MetaCyc:4.2.3.16-RXN 4S-(-)-limonene synthase activity|geranyldiphosphate diphosphate lyase [cyclizing, (4S)-limonene-forming]|geranyl-diphosphate diphosphate-lyase [cyclizing, (-)-(4S)-limonene-forming]|geranyldiphosphate diphosphate lyase (limonene forming)|(-)-(4S)-limonene synthase activity Catalysis of the reaction: geranyl diphosphate = (4S)-limonene + diphosphate. GO:0050553 taxadiene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050553 RHEA:20912|EC:4.2.3.17|KEGG_REACTION:R06305|MetaCyc:4.2.3.17-RXN geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, taxa-4,11-diene-forming)|geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, taxadiene-forming)|taxa-4(5),11(12)-diene synthase activity Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = diphosphate + taxa-4,11-diene. GO:0050558 maltose epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050558 MetaCyc:5.1.3.21-RXN|RHEA:21228|KEGG_REACTION:R07319|EC:5.1.3.21 maltose 1-epimerase activity Catalysis of the reaction: alpha-maltose = beta-maltose. GO:0050559 copalyl diphosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050559 MetaCyc:RXN-4861|RHEA:24316|EC:5.5.1.12|KEGG_REACTION:R06298 (+)-copalyl-diphosphate lyase (decyclizing)|diterpene cyclase activity Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = (+)-copalyl diphosphate. GO:0050556 deacetylisoipecoside synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050556 RHEA:21756|MetaCyc:4.3.3.3-RXN|EC:4.3.3.3|KEGG_REACTION:R05750 deacetylisoipecoside dopamine-lyase (secologanin-forming)|deacetylisoipecoside dopamine-lyase activity Catalysis of the reaction: deacetylisoipecoside + H(2)O = dopamine + secologanin. GO:0050557 deacetylipecoside synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050557 KEGG_REACTION:R05749|MetaCyc:4.3.3.4-RXN|EC:4.3.3.4|RHEA:12296 deacetylipecoside dopamine-lyase (secologanin-forming)|deacetylipecoside dopamine-lyase activity Catalysis of the reaction: deacetylipecoside + H(2)O = dopamine + secologanin. CL:0000253 eurydendroid cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000253 CHEBI:76492 trans-2-triacontenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76492 CL:0000255 eukaryotic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000255 CHEBI:76493 (2E,8Z,11Z,14Z,17Z,20Z,23Z)-hexacosaheptaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76493 CHEBI:76490 trans-octacos-2-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76490 CHEBI:76491 (3R,8Z,11Z,14Z,17Z,20Z,23Z)-hydroxyhexacosahexaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76491 CHEBI:76496 (3R,12Z,15Z,18Z,21Z,24Z,27Z)-3-hydroxytriacontahexaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76496 CHEBI:76497 (2E,12Z,15Z,18Z,21Z,24Z,27Z)-triacontaheptaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76497 CHEBI:76494 (3R,10Z,13Z,16Z,19Z,22Z,25Z)-3-hydroxyoctacosahexaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76494 CHEBI:76495 (2E,10Z,13Z,16Z,19Z,22Z,25Z)-octacosaheptaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76495 GO:0050550 pinene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050550 EC:4.2.3.14|MetaCyc:4.2.3.14-RXN geranyldiphosphate diphosphate lyase (pinene forming)|beta-geraniolene synthase activity|(-)-(1S,5S)-pinene synthase activity|geranyl-diphosphate diphosphate-lyase (cyclizing, pinene-forming) Catalysis of the reaction: geranyl diphosphate = pinene + diphosphate. GO:0050551 myrcene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050551 MetaCyc:RXN-5110|KEGG_REACTION:R02009|EC:4.2.3.15|RHEA:16965 geranyl-diphosphate diphosphate-lyase (myrcene-forming) activity Catalysis of the reaction: geranyl diphosphate = diphosphate + myrcene. CHEBI:76498 coral metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76498 GO:0050565 aerobactin synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050565 RHEA:11760|MetaCyc:6.3.2.27-RXN|KEGG_REACTION:R04357 citrate:6-N-acetyl-6-N-hydroxy-L-lysine ligase (ADP-forming)|citrate:N6-acetyl-N6-hydroxy-L-lysine ligase (ADP-forming) Catalysis of the reaction: 2 N(6)-acetyl-N(6)-hydroxy-L-lysine + 4 ATP + citrate + 2 H(2)O = 4 ADP + aerobactin + 8 H(+) + 4 phosphate. GO:0001598 obsolete chemokine receptor-like receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001598 chemokine receptor-like receptor activity OBSOLETE. (Was not defined before being made obsolete). GO:0050566 asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050566 Wikipedia:Asparaginyl-tRNA_synthase_(glutamine-hydrolysing)|MetaCyc:6.3.5.6-RXN|EC:6.3.5.6|RHEA:14513 Asp-tRNAAsn amidotransferase activity|asparaginyl-tRNA synthase (glutamine-hydrolysing)|aspartyl-tRNAAsn amidotransferase activity|Asp-tRNA(Asn) amidotransferase activity|aspartyl-tRNA(Asn) amidotransferase activity|aspartyl-tRNAAsn:L-glutamine amido-ligase (ADP-forming)|Asp-tRNAAsn:L-glutamine amido-ligase (ADP-forming)|Asp-AdT activity Catalysis of the reaction: L-glutamine + aspartyl-tRNA(Asn) + ATP = L-glutamate + asparaginyl-tRNA(Asn) + phosphate + ADP. GO:0001599 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001599 GO:0050563 trans-feruloyl-CoA synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050563 RHEA:19389|MetaCyc:6.2.1.34-RXN|EC:6.2.1.34 trans-ferulate:CoASH ligase (ATP-hydrolysing)|ferulate-CoA ligase activity|trans-feruloyl-CoA synthetase activity Catalysis of the reaction: ATP + CoA + trans-ferulate = (E)-feruloyl-CoA + ADP + phosphate. GO:0050564 N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050564 KEGG_REACTION:R04870|RHEA:23196|MetaCyc:6.3.2.26-RXN|EC:6.3.2.26 L-2-aminohexanedioate:L-cysteine:L-valine ligase (AMP-forming, valine-inverting)|L-delta-(alpha-aminoadipoyl)-L-cysteinyl-D-valine synthetase activity|ACV synthetase activity|L-alpha-aminoadipyl-cysteinyl-valine synthetase activity Catalysis of the reaction: L-2-aminoadipate + L-cysteine + L-valine + 3 ATP + H(2)O = N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + 3 AMP + 3 diphosphate + 6 H(+). GO:0050569 glycolaldehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050569 RHEA:20001|MetaCyc:GLYCOLALD-DEHYDROG-RXN|EC:1.2.1.21|KEGG_REACTION:R01333 glycol aldehyde dehydrogenase activity|glycolaldehyde:NAD+ oxidoreductase activity Catalysis of the reaction: glycolaldehyde + H(2)O + NAD(+) = glycolate + 2 H(+) + NADH. GO:0001594 trace-amine receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001594 Combining with a trace amine to initiate a change in cell activity. Trace amines are biogenic amines that are synthesized from aromatic amino acids and are substrates for monoamine oxidase, and are therefore detectable only at trace levels in mammals. GO:0001595 angiotensin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001595 Combining with angiotensin to initiate a change in cell activity. GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050567 Wikipedia:Glutaminyl-tRNA_synthase_(glutamine-hydrolysing)|RHEA:17521|MetaCyc:6.3.5.7-RXN|EC:6.3.5.7 Glu-tRNAGln amidotransferase activity|glutamyl-tRNA(Gln) amidotransferase activity|Glu-AdT activity|glutaminyl-tRNA synthase (glutamine-hydrolysing)|glutamyl-tRNAGln:L-glutamine amido-ligase (ADP-forming)|glutamyl-tRNAGln amidotransferase activity|Glu-tRNA(Gln) amidotransferase activity|Glu-tRNAGln:L-glutamine amido-ligase (ADP-forming) Catalysis of the reaction: L-glutamine + glutamyl-tRNA(Gln) + ATP = L-glutamate + glutaminyl-tRNA(Gln) + phosphate + ADP. GO:0001596 angiotensin type I receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001596 PLC-activating angiotensin receptor activity An angiotensin receptor activity that acts via Gq-mediated activation of phospholipase C followed by phosphoinositide hydrolysis and Ca2+ signaling, and may act via additional signaling mechanisms. GO:0050568 protein-glutamine glutaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050568 RHEA:16441|MetaCyc:CHEBDEAMID-RXN|EC:3.5.1.44 peptidylglutaminase II|glutaminylpeptide glutaminase activity|protein-L-glutamine amidohydrolase activity|glutaminyl-peptide glutaminase activity|destabilase activity|peptidoglutaminase II activity Catalysis of the reaction: protein L-glutamine + H2O = protein L-glutamate + NH3. GO:0001597 obsolete apelin-like receptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001597 APJ-like receptor|apelin-like receptor OBSOLETE. (Was not defined before being made obsolete). CL:0000226 single nucleate cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000226 A cell with a single nucleus. GO:0001590 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001590 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001591 dopamine D4 receptor activity|dopamine D3 receptor activity|dopamine D2 receptor activity Combining with the neurotransmitter dopamine and activating adenylate cyclase via coupling to Gi/Go to initiate a change in cell activity. CL:0000227 binucleate cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000227 CL:0000228 multinucleate cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000228 syncytium|syncytial cell|syncitium A cell with more than one nucleus. GO:0001592 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001592 GO:0001593 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001593 CHEBI:52490 cobalt-precorrin-7 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52490 CL:0000221 ectodermal cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000221 ectoderm cell A cell of the outer of the three germ layers of the embryo. CHEBI:52491 cobalt-sirohydrochlorin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52491 CL:0000222 mesodermal cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000222 mesoblast|mesoderm cell A cell of the middle germ layer of the embryo. CL:0000223 endodermal cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000223 endoderm cell A cell of the inner of the three germ layers of the embryo. CL:0000225 anucleate cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000225 non-nucleated cell A cell that lacks a nucleus. CHEBI:52499 cob(II)yrinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52499 GO:0050561 glutamate-tRNA(Gln) ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050561 RHEA:18397|MetaCyc:6.1.1.24-RXN|EC:6.1.1.24 L-glutamate:tRNAGlx ligase (AMP-forming)|nondiscriminating glutamyl-tRNA synthetase activity|glutamate-tRNAGln ligase activity Catalysis of the reaction: tRNA(Glx) + L-glutamate + ATP = glutamyl-tRNA(Glx) + diphosphate + AMP. GO:0050562 lysine-tRNA(Pyl) ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050562 MetaCyc:6.1.1.25-RXN lysine-tRNAPyl ligase activity|L-lysine:tRNAPyl ligase (AMP-forming) Catalysis of the reaction: tRNA(Pyl) + L-lysine + ATP = L-lysyl-tRNA(Pyl) + diphosphate + AMP. GO:0050560 aspartate-tRNA(Asn) ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050560 MetaCyc:6.1.1.23-RXN|EC:6.1.1.23|RHEA:18349 nondiscriminating aspartyl-tRNA synthetase activity|L-aspartate:tRNAAsx ligase (AMP-forming)|aspartate-tRNAAsn ligase activity Catalysis of the reaction: tRNA(Asx) + L-aspartate + ATP = aspartyl-tRNA(Asx) + diphosphate + AMP. GO:0050576 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050576 GO:0050577 GDP-L-fucose synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050577 Reactome:R-HSA-6787642|RHEA:18885|MetaCyc:1.1.1.271-RXN|EC:1.1.1.271 GDP-L-fucose:NADP+ 4-oxidoreductase (3,5-epimerizing)|GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase activity|GDP-fucose synthetase activity Catalysis of the reaction: GDP-L-fucose + NAD+ = GDP-4-dehydro-6-deoxy-D-mannose + NADH + H+. GO:0050574 2-(R)-hydroxypropyl-CoM dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050574 UM-BBD_reactionID:r0852|RHEA:13249|KEGG_REACTION:R05689|MetaCyc:1.1.1.268-RXN|EC:1.1.1.268 2-(2-(R)-hydroxypropylthio)ethanesulfonate dehydrogenase activity|2-[2-(R)-hydroxypropylthio]ethanesulfonate:NAD+ oxidoreductase activity Catalysis of the reaction: 2-(R)-hydroxypropyl-coenzyme M + NAD(+) = 2-oxopropyl-coenzyme M + H(+) + NADH. GO:0050575 2-(S)-hydroxypropyl-CoM dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050575 UM-BBD_reactionID:r0853|MetaCyc:1.1.1.269-RXN|RHEA:21052|KEGG_REACTION:R05690|EC:1.1.1.269 2-(2-(S)-hydroxypropylthio)ethanesulfonate dehydrogenase activity|2-[2-(S)-hydroxypropylthio]ethanesulfonate:NAD+ oxidoreductase activity Catalysis of the reaction: 2-(S)-hydroxypropyl-coenzyme M + NAD(+) = 2-oxopropyl-coenzyme M + H(+) + NADH. CHEBI:52489 cobalt-precorrin-5B biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52489 GO:0050578 (R)-2-hydroxyacid dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050578 RHEA:35735|MetaCyc:1.1.1.272-RXN|EC:1.1.1.272 (R)-sulfolactate:NAD(P)+ oxidoreductase activity|L-sulfolactate dehydrogenase activity|(R)-2-hydroxyacid:NAD(P)+ oxidoreductase activity|(R)-sulfolactate:NAD(P)(+) oxidoreductase activity Catalysis of the reaction: (S)-3-sulfolactate + NAD(P)+ = 3-sulfopyruvate + NAD(P)H + H+. GO:0050579 vellosimine dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050579 KEGG_REACTION:R05827|RHEA:20029|MetaCyc:1.1.1.273-RXN|EC:1.1.1.273 10-deoxysarpagine:NADP+ oxidoreductase activity Catalysis of the reaction: 10-deoxysarpagine + NADP(+) = H(+) + NADPH + vellosimine. CL:0000237 keratinizing barrier epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000237 CL:0000239 brush border epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000239 OPL:0000088 Triatominae midgut biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OPL_0000088 A midgut that is a part of or originated from a Triatominae bug. CL:0000232 erythrocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000232 red blood cell|RBC A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen. CL:0000233 platelet biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000233 enucleate thrombocyte|anucleate thrombocyte|blood platelet A non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation. CL:0000234 phagocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000234 Any cell capable of ingesting particulate matter via phagocytosis. CL:0000235 macrophage biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000235 histiocyte A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells. CL:0000236 B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000236 B-cell|B-lymphocyte|B lymphocyte A lymphocyte of B lineage that is capable of B cell mediated immunity. CHEBI:52485 isopimara-7,15-dienal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52485 CHEBI:52486 dehydroabietadienol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52486 CHEBI:52487 dehydroabietadienal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52487 CHEBI:52488 cobalt-precorrin-5A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52488 GO:0050572 L-idonate 5-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050572 MetaCyc:1.1.1.264-RXN|EC:1.1.1.264 L-idonate:NAD(P)+ oxidoreductase activity Catalysis of the reaction: L-idonate + NAD(P)+ = 5-dehydrogluconate + NAD(P)H + H+. GO:0050573 dTDP-4-dehydro-6-deoxyglucose reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050573 KEGG_REACTION:R05687|RHEA:36586|MetaCyc:1.1.1.266-RXN|EC:1.1.1.266 dTDP-D-fucose:NADP+ oxidoreductase activity|dTDP-4-keto-6-deoxyglucose reductase activity Catalysis of the reaction: dTDP-D-fucose + NADP(+) = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H(+) + NADPH. CHEBI:52482 levopimaradienol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52482 GO:0050570 4-hydroxythreonine-4-phosphate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050570 RHEA:32275|MetaCyc:1.1.1.262-RXN|EC:1.1.1.262 L-threonine 4-phosphate dehydrogenase activity|4-(phosphonooxy)-L-threonine:NAD+ oxidoreductase activity|PdxA|NAD(+)-dependent threonine 4-phosphate dehydrogenase activity|NAD+-dependent threonine 4-phosphate dehydrogenase activity|4-(phosphohydroxy)-L-threonine dehydrogenase activity Catalysis of the reaction: 4-(phosphonooxy)-threonine + NAD+ = 2-amino-3-oxo-4-phosphonooxybutyrate + NADH + H+. CHEBI:52483 levopimaradienal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52483 CHEBI:52484 isopimara-7,15-dienol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52484 GO:0050571 1,5-anhydro-D-fructose reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050571 RHEA:20665|KEGG_REACTION:R05682|MetaCyc:1.1.1.263-RXN|EC:1.1.1.263 1,5-anhydro-D-glucitol:NADP+ oxidoreductase activity|AF reductase activity Catalysis of the reaction: 1,5-anhydro-D-glucitol + NADP(+) = 1,5-anhydro-D-fructose + H(+) + NADPH. GO:0098521 inhibitory neuromuscular junction biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098521 The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential that inhibits muscle contraction. GO:0050587 chlorite O2-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050587 EC:1.13.11.49|MetaCyc:1.13.11.49-RXN|RHEA:21404|UM-BBD_reactionID:r0982|KEGG_REACTION:R05721 chloride:oxygen oxidoreductase activity|chlorite dismutase activity Catalysis of the reaction: chloride + O(2) = chlorite. GO:0001576 globoside biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001576 globoside anabolism|globoside synthesis|globoside formation|globoside biosynthesis The chemical reactions and pathways resulting in the formation of a ceramide with a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I). GO:0098522 neuromuscular junction of skeletal muscle fiber biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098522 A neuromuscular junction in which the target muscle cell is a skeletal muscle fiber. GO:0050588 apo-beta-carotenoid-14',13'-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050588 RHEA:26023|EC:1.13.11.67|MetaCyc:1.13.12.12-RXN|KEGG_REACTION:R08889 apo-b-carotenoid-14',13'-dioxygenase activity|8'-apo-beta-carotenol:O2 oxidoreductase activity Catalysis of the reaction: 8'-apo-beta-carotenol + O(2) = (E,E)-7-hydroxy-6-methylhepta-3,5-dienal + 14'-apo-beta-carotenal. GO:0001577 obsolete galectin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001577 galectin|S-type lectin OBSOLETE. A lectin that exhibits calcium independent binding of beta-galactoside sugars. GO:0050585 4-hydroxymandelate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050585 EC:1.13.11.46|MetaCyc:1.13.11.46-RXN|RHEA:21376 4-hydroxyphenylpyruvate:oxygen oxidoreductase (decarboxylating)|4-hydroxyphenylpyruvate dioxygenase II activity Catalysis of the reaction: 4-hydroxyphenylpyruvate + O2 = 4-hydroxymandelate + CO2. GO:0001578 microtubule bundle formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001578 microtubule bundling A process that results in a parallel arrangement of microtubules. GO:0098520 excitatory neuromuscular junction biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098520 The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a post-synaptic potential responsible for muscle contraction. GO:0050586 3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050586 EC:1.13.11.48|MetaCyc:1.13.11.48-RXN|KEGG_REACTION:R05720|RHEA:21572 1H-3-hydroxy-4-oxo quinaldine 2,4-dioxygenase activity|1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase activity|(1H)-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase activity|3-hydroxy-2-methyl-1H-quinolin-4-one 2,4-dioxygenase (CO-forming)|3-hydroxy-2-methyl-quinolin-4-one 2,4-dioxygenase activity Catalysis of the reaction: 3-hydroxy-2-methylquinolin-4(1H)-one + H(+) + O(2) = N-acetylanthranilate + CO. GO:0001579 medium-chain fatty acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001579 The directed movement of medium-chain fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A medium-chain fatty acid is a fatty acid with a chain length of between C6 and C12. GO:0001572 lactosylceramide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001572 lactosylceramide anabolism|lactosylceramide biosynthesis|lactosylceramide synthesis|lactosylceramide formation The chemical reactions and pathways resulting in the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. They are the precursors of both gangliosides and globosides. GO:0001573 ganglioside metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001573 ganglioside metabolism The chemical reactions and pathways involving ceramide oligosaccharides carrying in addition to other sugar residues, one or more sialic acid residues. GO:0001574 ganglioside biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001574 ganglioside biosynthesis|ganglioside anabolism|ganglioside synthesis|ganglioside formation The chemical reactions and pathways resulting in the formation of ceramide oligosaccharides carrying in addition to other sugar residues, one or more sialic acid residues. GO:0050589 leucocyanidin oxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050589 MetaCyc:RXN-602|EC:1.14.20.4 anthocyanidin synthase activity|leucocyanidin,2-oxoglutarate:oxygen oxidoreductase activity|leucoanthocyanidin hydroxylase|leucoanthocyanidin dioxygenase activity Catalysis of the reaction: leucocyanidin + 2-oxoglutarate + O2 = cis- or trans-dihydroquercetin + succinate + CO2 + 2 H2O. GO:0001575 globoside metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001575 globoside metabolism The chemical reactions and pathways involving globosides, globotetraosylceramides, ceramides containing a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I). Globosides are the major neutral glycosphingolipid in normal kidneys and erythrocytes. CL:0000205 thermoreceptor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000205 A cellular receptor which mediates the sense of temperature. Thermoreceptor cells in vertebrates are mostly located under the skin. In mammals there are separate types of thermoreceptors for cold and for warmth and pain receptor cells which detect cold or heat extreme enough to cause pain. GO:0001570 vasculogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001570 Wikipedia:Vasculogenesis vascular morphogenesis The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes. CL:0000206 chemoreceptor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000206 A cell specialized to detect chemical substances and relay that information centrally in the nervous system. Chemoreceptors may monitor external stimuli, as in taste and olfaction, or internal stimuli, such as the concentrations of oxygen and carbon dioxide in the blood. GO:0001571 non-tyrosine kinase fibroblast growth factor receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001571 non-tyrosine kinase FGFR activity|non-tyrosine kinase FGF receptor activity Combining with fibroblast growth factor (FGF) and transmitting the signal from one side of the membrane to the other by a mechanism independent of tyrosine kinase activity. CL:0000207 olfactory receptor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000207 olfactory sensory neuron|Schultze's cell|olfactory receptor neuron|odorant receptor cell CL:0000209 taste receptor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000209 taste bud cell A cell type found in the spherical or ovoid clusters of receptor cells found mainly in the epithelium of the tongue and constituting the end organs of the sense of taste. CL:0000200 touch receptor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000200 CL:0000202 auditory hair cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000202 inner ear receptor cell|inner ear hair cell|auditory receptor cell|cochlear hair cell A mechanoreceptor cell located in the inner ear that is sensitive to auditory stimuli. The accessory sensory structures are arranged so that appropriate stimuli cause movement of the hair-like projections (stereocilia and kinocilia) which relay the information centrally in the nervous system. CL:0000203 gravity sensitive cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000203 GO:0098529 neuromuscular junction development, skeletal muscle fiber biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098529 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction that targets a skeletal muscle fiber. GO:0050580 2,5-didehydrogluconate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050580 MetaCyc:1.1.1.274-RXN|EC:1.1.1.274|RHEA:23828 YqhE reductase|2-dehydro-D-gluconate:NADP+ 2-oxidoreductase activity|2,5-diketo-D-gluconate reductase activity Catalysis of the reaction: 2-dehydro-D-gluconate + NADP+ = 2,5-didehydro-D-gluconate + NADPH + H+. GO:0098527 neuromuscular junction of somatic muscle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098527 A neuromuscular junction in which the target muscle cell is a somatic muscle cell, such as those found in nematodes and arthropods. GO:0098528 skeletal muscle fiber differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098528 The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle fiber cell. Skeletal muscle fiber differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual skeletal muscle fibers fuse to form bigger myotubes and start to contract. GO:0050583 hydrogen dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050583 EC:1.12.1.3|MetaCyc:1.12.1.3-RXN|RHEA:18637 NADP-linked hydrogenase activity|hydrogen:NADP+ oxidoreductase activity|NADP-reducing hydrogenase activity Catalysis of the reaction: NADP+ + H2 = NADPH + H+. GO:0098525 excitatory neuromuscular junction of somatic myotube biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098525 A neuromuscular junction that functions in the excitation of somatic muscle myotubes, such as an arthropod somatic muscle cells. GO:0050584 linoleate 11-lipoxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050584 RHEA:18993|EC:1.13.11.45|KEGG_REACTION:R05718|MetaCyc:1.13.11.45-RXN manganese lipoxygenase activity|linoleate dioxygenase activity|linoleate:oxygen 11S-oxidoreductase activity Catalysis of the reaction: linoleate + O(2) = (9Z,11S,12Z)-11-hydroperoxyoctadeca-9,12-dienoate. GO:0098526 inhibitory neuromuscular junction of somatic myotube biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098526 A neuromuscular junction that functions in the inhibition of somatic muscle myotube contraction. Examples of somatic muscle myotubes include the somatic muscle cells of arthropods. GO:0098523 neuromuscular junction of myotube biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098523 A neuromuscular junction in which the target muscle cell is a myotube. GO:0050581 D-mannitol oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050581 MetaCyc:1.1.3.40-RXN|EC:1.1.3.40|RHEA:18513 mannitol oxidase activity|D-arabitol oxidase activity|D-arabinitol oxidase activity|mannitol:oxygen oxidoreductase (cyclizing) Catalysis of the reaction: mannitol + O2 = mannose + H2O2. GO:0050582 xylitol oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050582 MetaCyc:1.1.3.41-RXN|EC:1.1.3.41 xylitol:oxygen oxidoreductase activity Catalysis of the reaction: xylitol + O2 = xylose + H2O2. GO:0098524 neuromuscular junction of somatic muscle myotube biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098524 A neuromuscular junction in which the target muscle cell is a somatic muscle myotube, such as an arthropod somatic muscle cell. GO:0050598 taxane 13-alpha-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050598 RHEA:18949|KEGG_REACTION:R06308|MetaCyc:1.14.13.77-RXN|EC:1.14.14.106 taxa-4(20),11-dien-5alpha-ol,NADPH:oxygen oxidoreductase (13alpha-hydroxylating)|taxane 13alpha-hydroxylase activity|taxane 13a-hydroxylase activity Catalysis of the reaction: H(+) + NADPH + O(2) + taxa-4(20),11-dien-5alpha-ol = H(2)O + NADP(+) + taxa-4(20),11-dien-5alpha,13alpha-diol. GO:0001587 Gq/11-coupled serotonin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001587 5-HT2 receptor activity|serotonin receptor activity, coupled via Gq/11 Combining with serotonin and transmitting the signal across the membrane by activation of the Gq/11 subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gq/11 subunit subsequently activates phospholipase C and results in an increase in inositol triphosphate (IP3) levels. GO:0098532 histone H3-K27 trimethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098532 The modification of histone H3 by addition of three methyl groups to lysine at position 27 of the histone. GO:0050599 deacetoxycephalosporin-C synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050599 RHEA:20748|EC:1.14.20.1|KEGG_REACTION:R05301|MetaCyc:1.14.20.1-RXN expandase activity|penicillin-N,2-oxoglutarate:oxygen oxidoreductase (ring-expanding)|penicillin N expandase activity|DAOCS activity|DAOC synthase activity|deacetoxycephalosporin C synthetase activity Catalysis of the reaction: 2-oxoglutarate + O(2) + penicillin N = CO(2) + deacetoxycephalosporin C + H(2)O + succinate. GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001588 dopamine D1 receptor activity|dopamine D5 receptor activity Combining with the neurotransmitter dopamine and activating adenylate cyclase via coupling to Gs to initiate a change in cell activity. GO:0098533 ATPase dependent transmembrane transport complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098533 A transmembrane protein complex that functions in ATPase dependent active transport across a membrane. GO:0098530 positive regulation of strand invasion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098530 positive regulation of Rad51-mediated strand invasion|positive regulation of D-loop biosynthesis|positive regulation of D-loop formation Any process that increases the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules. GO:0050596 vinorine hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050596 KEGG_REACTION:R05877|MetaCyc:1.14.13.75-RXN|RHEA:17257|EC:1.14.14.104 vinorine,NADPH:oxygen oxidoreductase (21alpha-hydroxylating) Catalysis of the reaction: H(+) + NADPH + O(2) + vinorine = H(2)O + NADP(+) + vomilenine. GO:0001589 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001589 GO:0098531 ligand-activated transcription factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098531 transcription factor activity, direct ligand regulated sequence-specific DNA binding|direct ligand regulated sequence-specific DNA binding transcription factor activity A DNA-binding transcription factor activity regulated by binding to a ligand and that modulates the transcription of specific gene sets. Examples include the lac and trp repressors in E.coli and steroid hormone receptors. GO:0050597 taxane 10-beta-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050597 KEGG_REACTION:R06309|MetaCyc:1.14.13.76-RXN|RHEA:15241|EC:1.14.14.105 taxane 10b-hydroxylase activity|taxane 10beta-hydroxylase activity|taxa-4(20),11-dien-5alpha-yl acetate,NADPH:oxygen oxidoreductase (10beta-hydroxylating)|5-alpha-taxadienol-10-beta-hydroxylase activity Catalysis of the reaction: H(+) + NADPH + O(2) + taxa-4(20),11-dien-5alpha-yl acetate = 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + H(2)O + NADP(+). GO:0001583 detection of chemical stimulus involved in sensory perception of salty taste biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001583 perception of salty taste, sensory transduction of chemical stimulus|salty taste detection|perception of salty taste, detection of chemical stimulus|sensory detection of chemical stimulus during perception of salty taste|sensory transduction of salty taste|sensory transduction of chemical stimulus during perception of salty taste|sensory detection of salty taste The series of events required for a salty taste stimulus to be received and converted to a molecular signal. GO:0001584 obsolete rhodopsin-like receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001584 Class A G-protein coupled receptor|class A orphan receptor activity|Class A GPCR|Class A G protein coupled receptor|rhodopsin-like receptor activity OBSOLETE. A G protein-coupled receptor that is structurally/functionally related to the rhodopsin receptor. CHEBI:52469 precorrin-1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52469 GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902108 regulation of mitochondrial membrane permeability involved in apoptotic programmed cell death|regulation of transport across mitochondrial membrane involved in apoptotic program|regulation of mitochondrial membrane permeability involved in apoptotic program|regulation of mitochondrial membrane permeability involved in programmed cell death by apoptosis|regulation of mitochondrial membrane permeability involved in signaling (initiator) caspase activity|regulation of transport across mitochondrial membrane involved in programmed cell death by apoptosis|regulation of mitochondrial membrane permeability involved in type I programmed cell death|regulation of mitochondrial membrane permeability involved in apoptotic cell death|regulation of transport across mitochondrial membrane involved in signaling (initiator) caspase activity|regulation of transport across mitochondrial membrane involved in type I programmed cell death|regulation of transport across mitochondrial membrane involved in apoptotic cell death|regulation of transport across mitochondrial membrane involved in apoptosis|regulation of transport across mitochondrial membrane involved in apoptotic process|regulation of mitochondrial membrane permeability involved in apoptosis|regulation of transport across mitochondrial membrane involved in apoptotic programmed cell death Any regulation of mitochondrial membrane permeability that is involved in apoptotic process. GO:0001585 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001585 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902109 negative regulation of transport across mitochondrial membrane involved in apoptosis|negative regulation of mitochondrial membrane permeability involved in type I programmed cell death|negative regulation of mitochondrial membrane permeability involved in signaling (initiator) caspase activity|negative regulation of transport across mitochondrial membrane involved in programmed cell death by apoptosis|mitochondrial membrane impermeability involved in programmed cell death by apoptosis|mitochondrial membrane impermeability involved in signaling (initiator) caspase activity|negative regulation of mitochondrial membrane permeability involved in apoptotic cell death|negative regulation of mitochondrial membrane permeability involved in apoptosis|negative regulation of transport across mitochondrial membrane involved in type I programmed cell death|negative regulation of transport across mitochondrial membrane involved in signaling (initiator) caspase activity|negative regulation of transport across mitochondrial membrane involved in apoptotic process|negative regulation of transport across mitochondrial membrane involved in apoptotic programmed cell death|negative regulation of transport across mitochondrial membrane involved in apoptotic cell death|mitochondrial membrane impermeability involved in apoptotic cell death|negative regulation of transport across mitochondrial membrane involved in apoptotic program|mitochondrial membrane impermeability involved in type I programmed cell death|negative regulation of mitochondrial membrane permeability involved in apoptotic programmed cell death|mitochondrial membrane impermeability involved in apoptosis|mitochondrial membrane impermeabilization involved in apoptotic process|mitochondrial membrane impermeability involved in apoptotic process|mitochondrial membrane impermeabilization involved in apoptosis|mitochondrial membrane impermeabilization involved in programmed cell death by apoptosis|mitochondrial membrane impermeability involved in apoptotic programmed cell death|mitochondrial membrane impermeabilization involved in apoptotic programmed cell death|negative regulation of mitochondrial membrane permeability involved in apoptotic program|mitochondrial membrane impermeabilization involved in apoptotic cell death|mitochondrial membrane impermeabilization involved in apoptotic program|mitochondrial membrane impermeabilization involved in signaling (initiator) caspase activity|mitochondrial membrane impermeabilization involved in type I programmed cell death|mitochondrial membrane impermeability involved in apoptotic program|negative regulation of mitochondrial membrane permeability involved in programmed cell death by apoptosis Any negative regulation of mitochondrial membrane permeability that is involved in apoptotic process. GO:0001586 Gi/o-coupled serotonin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001586 serotonin receptor activity, coupled via Gi/o|5-HT1 receptor activity Combining with serotonin and transmitting the signal across the membrane by activation of the Gi/o subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gi/o subunit subsequently inhibits adenylate cyclase and results in a decrease in cyclic AMP (cAMP) levels. GO:1902106 negative regulation of leukocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902106 inhibition of leukocyte differentiation|down-regulation of immune cell differentiation|negative regulation of immune cell differentiation|down regulation of leucocyte differentiation|downregulation of leucocyte differentiation|inhibition of immune cell differentiation|down regulation of leukocyte differentiation|downregulation of leukocyte differentiation|negative regulation of leucocyte differentiation|down-regulation of leucocyte differentiation|down regulation of immune cell differentiation|inhibition of leucocyte differentiation|downregulation of immune cell differentiation|down-regulation of leukocyte differentiation Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte differentiation. CL:0000215 barrier cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000215 A cell whose primary function is to prevent the transport of stuff across compartments. GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001580 sensory detection of bitter taste|sensory transduction of chemical stimulus during perception of bitter taste|sensory detection of chemical stimulus during perception of bitter taste|perception of bitter taste, sensory transduction of chemical stimulus|sensory transduction of bitter taste|bitter taste detection|perception of bitter taste, detection of chemical stimulus The series of events required for a bitter taste stimulus to be received and converted to a molecular signal. GO:1902107 positive regulation of leukocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902107 activation of immune cell differentiation|positive regulation of immune cell differentiation|up-regulation of leukocyte differentiation|upregulation of leucocyte differentiation|up-regulation of immune cell differentiation|upregulation of leukocyte differentiation|up regulation of leucocyte differentiation|activation of leucocyte differentiation|positive regulation of leucocyte differentiation|upregulation of immune cell differentiation|up regulation of leukocyte differentiation|activation of leukocyte differentiation|up-regulation of leucocyte differentiation|up regulation of immune cell differentiation Any process that activates or increases the frequency, rate or extent of leukocyte differentiation. CL:0000216 Sertoli cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000216 A supporting cell projecting inward from the basement membrane of seminiferous tubules. They surround and nourish the developing male germ cells and secrete androgen binding protein. Their tight junctions with the spermatogonia and spermatocytes provide a blood-testis barrier. GO:0001581 detection of chemical stimulus involved in sensory perception of sour taste biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001581 sensory detection of sour taste|sensory transduction of chemical stimulus during perception of sour taste|sensory transduction of sour taste|sensory detection of chemical stimulus during perception of sour taste|sour taste detection|perception of sour taste, sensory transduction of chemical stimulus|perception of sour taste, detection of chemical stimulus The series of events required for a sour taste stimulus to be received and converted to a molecular signal. GO:1902104 positive regulation of metaphase/anaphase transition of meiotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902104 upregulation of metaphase/anaphase transition of meiotic cell cycle|activation of meiotic metaphase/anaphase transition|up-regulation of meiotic metaphase/anaphase transition|up regulation of metaphase/anaphase transition of meiotic cell cycle|activation of metaphase/anaphase transition of meiotic cell cycle|upregulation of meiotic metaphase/anaphase transition|up-regulation of metaphase/anaphase transition of meiotic cell cycle|up regulation of meiotic metaphase/anaphase transition|positive regulation of meiotic metaphase/anaphase transition Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle. CL:0000217 insulating cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000217 GO:1902105 regulation of leukocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902105 regulation of leucocyte differentiation|regulation of immune cell differentiation Any process that modulates the frequency, rate or extent of leukocyte differentiation. CL:0000218 myelinating Schwann cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000218 peripheral neuroglial cell|Schwann cell|neurilemmal cell A neuroglial cell of the peripheral nervous system which forms the insulating myelin sheaths of peripheral axons. GO:0001582 detection of chemical stimulus involved in sensory perception of sweet taste biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001582 sensory transduction of sweet taste|sensory detection of chemical stimulus during perception of sweet taste|sensory detection of sweet taste|sensory transduction of chemical stimulus during perception of sweet taste|perception of sweet taste, sensory transduction of chemical stimulus|sweet taste detection|perception of sweet taste, detection of chemical stimulus The series of events required for a sweet taste stimulus to be received and converted to a molecular signal. GO:1902102 regulation of metaphase/anaphase transition of meiotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902102 regulation of meiotic metaphase/anaphase transition Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle. CL:0000219 motile cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000219 A cell that moves by its own activities. GO:1902103 negative regulation of metaphase/anaphase transition of meiotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902103 negative regulation of meiotic metaphase/anaphase transition|down-regulation of meiotic metaphase/anaphase transition|down regulation of metaphase/anaphase transition of meiotic cell cycle|downregulation of metaphase/anaphase transition of meiotic cell cycle|inhibition of meiotic metaphase/anaphase transition|down-regulation of metaphase/anaphase transition of meiotic cell cycle|down regulation of meiotic metaphase/anaphase transition|inhibition of metaphase/anaphase transition of meiotic cell cycle|downregulation of meiotic metaphase/anaphase transition Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle. GO:1902100 negative regulation of metaphase/anaphase transition of cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902100 down-regulation of metaphase/anaphase transition of cell cycle|inhibition of metaphase/anaphase transition of cell cycle|down regulation of metaphase/anaphase transition of cell cycle|downregulation of metaphase/anaphase transition of cell cycle Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of cell cycle. GO:1902101 positive regulation of metaphase/anaphase transition of cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902101 up-regulation of metaphase/anaphase transition of cell cycle|upregulation of metaphase/anaphase transition of cell cycle|up regulation of metaphase/anaphase transition of cell cycle|activation of metaphase/anaphase transition of cell cycle Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of cell cycle. GO:1902110 positive regulation of mitochondrial membrane permeability involved in apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902110 mitochondrial membrane permeabilization involved in type I programmed cell death|mitochondrial permeability transition involved in apoptotic program|mitochondrial membrane permeabilization involved in signaling (initiator) caspase activity|mitochondrial membrane permeability transition involved in apoptotic program|mitochondrial membrane permeability transition involved in apoptotic cell death|mitochondrial membrane permeability transition involved in signaling (initiator) caspase activity|mitochondrial membrane permeability transition involved in type I programmed cell death|mitochondrial permeability transition involved in apoptotic cell death|mitochondrial membrane permeabilization involved in apoptotic program|positive regulation of transport across mitochondrial membrane involved in apoptosis|mitochondrial permeability transition involved in signaling (initiator) caspase activity|mitochondrial permeability transition involved in type I programmed cell death|positive regulation of mitochondrial membrane permeability involved in programmed cell death by apoptosis|positive regulation of mitochondrial membrane permeability involved in apoptosis|positive regulation of transport across mitochondrial membrane involved in apoptotic process|positive regulation of transport across mitochondrial membrane involved in apoptotic programmed cell death|positive regulation of mitochondrial membrane permeability involved in type I programmed cell death|positive regulation of mitochondrial membrane permeability involved in signaling (initiator) caspase activity|positive regulation of transport across mitochondrial membrane involved in programmed cell death by apoptosis|positive regulation of transport across mitochondrial membrane involved in apoptotic program|positive regulation of mitochondrial membrane permeability involved in apoptotic programmed cell death|positive regulation of mitochondrial membrane permeability involved in apoptotic cell death|mitochondrial permeability transition involved in apoptosis|mitochondrial permeability transition involved in apoptotic process|positive regulation of transport across mitochondrial membrane involved in type I programmed cell death|positive regulation of transport across mitochondrial membrane involved in signaling (initiator) caspase activity|mitochondrial permeability transition involved in apoptotic programmed cell death|mitochondrial membrane permeabilization involved in programmed cell death by apoptosis|mitochondrial membrane permeability transition involved in apoptotic process|mitochondrial membrane permeability transition involved in apoptosis|positive regulation of mitochondrial membrane permeability involved in apoptotic program|mitochondrial membrane permeability transition involved in apoptotic programmed cell death|positive regulation of transport across mitochondrial membrane involved in apoptotic cell death|mitochondrial membrane permeability transition involved in programmed cell death by apoptosis|mitochondrial membrane permeabilization involved in apoptotic process|mitochondrial membrane permeabilization involved in apoptosis|mitochondrial membrane permeabilization involved in apoptotic programmed cell death|mitochondrial permeability transition involved in programmed cell death by apoptosis|mitochondrial membrane permeabilization involved in apoptotic cell death Any positive regulation of mitochondrial membrane permeability that is involved in apoptotic process. CL:0000210 photoreceptor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000210 A cell specialized to detect and transduce light. CL:0000211 electrically active cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000211 A cell whose function is determined by the generation or the reception of an electric signal. CL:0000212 absorptive cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000212 A cell that takes up and metabolizes substances. CL:0000213 lining cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000213 boundary cell A cell within an epithelial cell sheet whose main function is to act as an internal or external covering for a tissue or an organism. GO:0050590 desacetoxyvindoline 4-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050590 KEGG_REACTION:R05857|MetaCyc:1.14.11.20-RXN|RHEA:18973|EC:1.14.11.20 desacetyoxyvindoline-17-hydroxylase activity|D17H activity|desacetoxyvindoline,2-oxoglutarate:oxygen oxidoreductase (4beta-hydroxylating)|desacetoxyvindoline-4-hydroxylase activity|desacetoxyvindoline,2-oxoglutarate:oxygen oxidoreductase (4-beta-hydroxylating) activity|deacetoxyvindoline,2-oxoglutarate:oxygen oxidoreductase (4beta-hydroxylating) Catalysis of the reaction: desacetoxyvindoline + 2-oxoglutarate + O2 = desacetylvindoline + succinate + CO2. CHEBI:52463 fusicocca-2,10(14)-diene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52463 GO:0050591 quinine 3-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050591 KEGG_REACTION:R05727|RHEA:20149|MetaCyc:1.14.13.67-RXN|EC:1.14.14.55 nifedipine oxidase activity|quinine 3-hydroxylase activity|quinine,NADPH:oxygen oxidoreductase activity Catalysis of the reaction: H(+) + NADPH + O(2) + quinine = 3-hydroxyquinine + H(2)O + NADP(+). CHEBI:52464 jasmonate ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52464 GO:0098538 lumenal side of transport vesicle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098538 internal side of transport vesicle membrane The side (leaflet) of the transport vesicle membrane that faces the lumen. GO:0098539 cytoplasmic side of transport vesicle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098539 external side of transport vesicle membrane The side (leaflet) of the transport vesicle membrane that faces the cytoplasm. GO:0098536 deuterosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098536 A spherical, electron dense, cytoplasmic structure that is involved in de novo assembly of centrioles. GO:0050594 tabersonine 16-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050594 KEGG_REACTION:R05855|MetaCyc:1.14.13.73-RXN|RHEA:14133|EC:1.14.14.103 tabersonine,NADPH:oxygen oxidoreductase (16-hydroxylating) Catalysis of the reaction: H(+) + NADPH + O(2) + tabersonine = 16-hydroxytabersonine + H(2)O + NADP(+). GO:0050595 7-deoxyloganin 7-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050595 RHEA:11452|MetaCyc:1.14.13.74-RXN|EC:1.14.13.74 7-deoxyloganin,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) Catalysis of the reaction: 7-deoxyloganin + NADPH + H+ + O2 = loganin + NADP+ + H2O. GO:0098537 lobed nucleus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098537 Nucleus with two or more lobes connected by a thin filament that contains no internal chromatin. Examples include the nuclei of mature basophils, eosinophils and neutrophils in mice and humans. GO:0050592 4-hydroxyphenylacetaldehyde oxime monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050592 KEGG_REACTION:R05728|MetaCyc:1.14.13.68-RXN|RHEA:18401|EC:1.14.14.37 4-hydroxybenzeneacetaldehyde oxime monooxygenase activity|cytochrome P450-II-dependent monooxygenase activity|NADPH-cytochrome P450 reductase (CYP71E1)|(Z)-4-hydroxyphenylacetaldehyde oxime,NADPH:oxygen oxidoreductase activity|CYP71E1 activity|cytochrome P450II-dependent monooxygenase activity|4-hydroxyphenylacetaldehyde oxime,NADPH:oxygen oxidoreductase activity Catalysis of the reaction: (Z)-(4-hydroxyphenyl)acetaldehyde oxime + H(+) + NADPH + O(2) = (S)-4-hydroxymandelonitrile + 2 H(2)O + NADP(+). GO:0098534 centriole assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098534 A cellular process that results in the assembly of one or more centrioles. CHEBI:52461 elisabethatriene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52461 GO:0098535 de novo centriole assembly involved in multi-ciliated epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098535 centriole amplification|multiciliation|deuterosomal basal body biogenesis|multiciliogenesis|deuterosome-mediated centriole biogenesis|de novo centriole assembly via deuterosome|deuterosome pathway|de novo centriole assembly Centriole assembly in which a centriole arises de novo by a process involving an electron-dense structure known as a deuterosome, rather than by duplication of an existing centriole, and occurring as part of multi-ciliated epithelial cell differentiation. GO:0050593 N-methylcoclaurine 3'-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050593 RHEA:16649|KEGG_REACTION:R05732|MetaCyc:1.14.13.71-RXN|EC:1.14.14.102 cytochrome P450 80B1 activity|(S)-N-methylcoclaurine 3'-hydroxylase activity|N-methylcoclaurine 3'-hydroxylase activity|(S)-N-methylcoclaurine,NADPH:oxygen oxidoreductase (3'-hydroxylating) Catalysis of the reaction: (S)-N-methylcoclaurine + H(+) + NADPH + O(2) = (S)-3'-hydroxy-N-methylcoclaurine + H(2)O + NADP(+). GO:0001554 luteolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001554 Wikipedia:Luteolysis The lysis or structural demise of the corpus luteum. During normal luteolysis, two closely related events occur. First, there is loss of the capacity to synthesize and secrete progesterone (functional luteolysis) followed by loss of the cells that comprise the corpus luteum (structural luteolysis). Preventing luteolysis is crucial to maintain pregnancy. GO:0001555 oocyte growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001555 The developmental growth process in which an oocyte irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present. GO:0001556 oocyte maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001556 Wikipedia:Oocyte_maturation A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization. GO:0001557 obsolete metabolic process resulting in cell growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001557 metabolic process resulting in cell growth OBSOLETE. The chemical reactions that occur in living organisms that result in an increase in the mass (size) of a cell. GO:0001550 ovarian cumulus expansion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001550 ovarian cumulus growth Increase in size of the cumulus surrounding the oocyte including change in morphology due to proliferation and dispersion of cumulus cells. GO:0001551 ovarian follicle endowment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001551 Association of oocytes with supporting epithelial granulosa cells to form primordial follicles. GO:1902119 regulation of meiotic spindle elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902119 regulation of spindle elongation during meiosis Any process that modulates the frequency, rate or extent of meiotic spindle elongation. GO:0001552 ovarian follicle atresia biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001552 A periodic process in which immature ovarian follicles degenerate and are subsequently re-absorbed. GO:0001553 luteinization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001553 Wikipedia:Luteal_phase|Wikipedia:Luteinization luteal phase The set of processes resulting in differentiation of theca and granulosa cells into luteal cells and in the formation of a corpus luteum after ovulation. GO:1902117 positive regulation of organelle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902117 up regulation of organelle assembly|upregulation of organelle assembly|activation of organelle assembly|up-regulation of organelle assembly Any process that activates or increases the frequency, rate or extent of organelle assembly. GO:1902118 calcidiol binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1902118 25OHD3 binding|25-hydroxyvitamin D3 binding|25(OH)D3 binding|25-hydroxycholecalciferol binding|calcifediol binding Interacting selectively and non-covalently with calcidiol. GO:1902115 regulation of organelle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902115 Any process that modulates the frequency, rate or extent of organelle assembly. GO:1902116 negative regulation of organelle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902116 down-regulation of organelle assembly|downregulation of organelle assembly|down regulation of organelle assembly|inhibition of organelle assembly Any process that stops, prevents or reduces the frequency, rate or extent of organelle assembly. CHEBI:27499 N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosylceramide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27499 GO:1902113 nucleotide phosphorylation involved in DNA repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902113 Any nucleotide phosphorylation that is involved in DNA repair. GO:1902114 D-valine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902114 D-valine metabolism The chemical reactions and pathways involving D-valine. CHEBI:27493 juvenile hormone III biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27493 GO:1902111 response to diethyl maleate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902111 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diethyl maleate stimulus. GO:1902112 cellular response to diethyl maleate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902112 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diethyl maleate stimulus. GO:1902120 negative regulation of meiotic spindle elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902120 downregulation of meiotic spindle elongation|inhibition of spindle elongation during meiosis|down regulation of meiotic spindle elongation|inhibition of meiotic spindle elongation|down regulation of spindle elongation during meiosis|downregulation of spindle elongation during meiosis|negative regulation of spindle elongation during meiosis|down-regulation of spindle elongation during meiosis|down-regulation of meiotic spindle elongation Any process that stops, prevents or reduces the frequency, rate or extent of meiotic spindle elongation. GO:1902121 lithocholic acid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1902121 LCA binding Interacting selectively and non-covalently with lithocholic acid. GO:0098509 sensory perception of humidity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098509 hygrosensory perception The series of events required for an organism to detect some level of humidity in its environment, convert this detection into a molecular signal, and recognize and characterize the signal. This is a neurological process. GO:0098507 polynucleotide 5' dephosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098507 The process of removing one or more phosphate groups from the 5' end of a polynucleotide. GO:0098508 endothelial to hematopoietic transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098508 The generation of hematopoietic stem cells from hemogenic endothelial cells by a process that includes tight-junction dissolution and loss of cell polarity followed by delamination from the endothelium. GO:0098505 G-rich strand telomeric DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098505 Interacting selectively and non-covalently with G-rich, single-stranded, telomere-associated DNA. GO:0098506 polynucleotide 3' dephosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098506 The process of removing one or more phosphate groups from the 3' end of a polynucleotide. GO:0098503 obsolete DNA 3' dephosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098503 OBSOLETE. The process of removing a 3' phosphate group from a DNA molecule. GO:0001558 regulation of cell growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001558 Any process that modulates the frequency, rate, extent or direction of cell growth. GO:0001559 obsolete regulation of cell growth by detection of nuclear:cytoplasmic ratio biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001559 interpretation of nuclear:cytoplasmic ratio to regulate cell growth|regulation of cell growth by sensing of nuclear:cytoplasmic ratio|regulation of cell growth by nuclear:cytoplasmic ratio|detection of nuclear:cytoplasmic ratio to regulate cell growth OBSOLETE. Any process in which the size of the nucleus with respect to the cytoplasm modulates the frequency, rate or extent of cell growth, the irreversible increase in size of a cell over time. GO:0098504 obsolete DNA 3' dephosphorylation involved in DNA repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098504 OBSOLETE. Any 3' DNA dephosphorylation that is involved in the process of DNA repair. CHEBI:52450 2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52450 GO:0098501 polynucleotide dephosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098501 The process of removing one or more phosphate groups from a polynucleotide. GO:0098502 DNA dephosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098502 The process of removing one or more phosphate groups from a DNA molecule. GO:0098510 sensory perception of high humidity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098510 The series of events required for an organism to detect high environmental humidity, convert this detection into a molecular signal, and recognize and characterize the signal. This is a neurological process. GO:0001565 phorbol ester receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001565 Combining with a phorbol ester and transmitting the signal to initiate a change in cell activity. CHEBI:52449 5-oxo-ETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52449 GO:0098511 sensory perception of low humidity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098511 The series of events required for an organism to detect low environmental humidity, convert this detection into a molecular signal, and recognize and characterize the signal. This is a neurological process. GO:0001566 non-kinase phorbol ester receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001566 Combining with a phorbol ester and transmitting the signal by a mechanism independent of kinase activity. GO:0001567 cholesterol 25-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001567 EC:1.14.99.38|MetaCyc:1.14.99.38-RXN|RHEA:21104|KEGG_REACTION:R07218 cholesterol 25-monooxygenase activity|cholesterol,hydrogen-donor:oxygen oxidoreductase (25-hydroxylating) activity Catalysis of the reaction: AH(2) + cholesterol + O(2) = 25-hydroxycholesterol + A + H(2)O. GO:0001568 blood vessel development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001568 The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood. GO:0001561 fatty acid alpha-oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001561 MetaCyc:PWY-2501 A metabolic pathway by which 3-methyl branched fatty acids are degraded. These compounds are not degraded by the normal peroxisomal beta-oxidation pathway, because the 3-methyl blocks the dehydrogenation of the hydroxyl group by hydroxyacyl-CoA dehydrogenase. The 3-methyl branched fatty acid is converted in several steps to pristenic acid, which can then feed into the beta-oxidative pathway. GO:0001562 response to protozoan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001562 response to protozoa|resistance to pathogenic protozoa|response to protozoon Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a protozoan. CHEBI:52447 tetrahydrodictyopterin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52447 GO:0001563 detection of protozoan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001563 detection of protozoa|detection of protozoon|perception of protozoa The series of events in which a stimulus from a protozoan is received and converted into a molecular signal. GO:0001564 obsolete resistance to pathogenic protozoa biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001564 resistance to pathogenic protozoa OBSOLETE. (Was not defined before being made obsolete). CHEBI:52448 amino monocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52448 GO:1902128 (-)-lariciresinol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902128 (-)-lariciresinol degradation|(-)-lariciresinol breakdown|(-)-lariciresinol catabolism The chemical reactions and pathways resulting in the breakdown of (-)-lariciresinol. GO:1902129 (-)-lariciresinol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902129 (-)-lariciresinol biosynthesis|(-)-lariciresinol anabolism|(-)-lariciresinol synthesis|(-)-lariciresinol formation The chemical reactions and pathways resulting in the formation of (-)-lariciresinol. GO:1902126 (+)-pinoresinol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902126 (+)-pinoresinol anabolism|(+)-pinoresinol synthesis|(+)-pinoresinol formation|(+)-pinoresinol biosynthesis The chemical reactions and pathways resulting in the formation of (+)-pinoresinol. GO:1902127 (-)-lariciresinol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902127 (-)-lariciresinol metabolism The chemical reactions and pathways involving (-)-lariciresinol. GO:0001560 regulation of cell growth by extracellular stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001560 regulation of growth by exogenous stimulus|regulation of growth by exogenous stimuli|regulation of growth by external stimuli|regulation of cell growth by sensing of exogenous stimulus|regulation of growth by external signal|regulation of cell growth by detection of exogenous stimulus|regulation of growth by exogenous signal|interpretation of external signals that regulate cell growth|regulation of growth by external stimulus Any process in which external signals modulate the frequency, rate or extent of cell growth, the irreversible increase in size of a cell over time. GO:1902124 (+)-pinoresinol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902124 (+)-pinoresinol metabolism The chemical reactions and pathways involving (+)-pinoresinol. GO:1902125 (+)-pinoresinol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902125 (+)-pinoresinol breakdown|(+)-pinoresinol catabolism|(+)-pinoresinol degradation The chemical reactions and pathways resulting in the breakdown of (+)-pinoresinol. GO:1902122 chenodeoxycholic acid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1902122 CDCA binding Interacting selectively and non-covalently with chenodeoxycholic acid. GO:1902123 (-)-pinoresinol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902123 (-)-pinoresinol degradation|(-)-pinoresinol breakdown|(-)-pinoresinol catabolism The chemical reactions and pathways resulting in the breakdown of (-)-pinoresinol. GO:1902131 (+)-lariciresinol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902131 (+)-lariciresinol degradation|(+)-lariciresinol breakdown|(+)-lariciresinol catabolism The chemical reactions and pathways resulting in the breakdown of (+)-lariciresinol. GO:1902132 (+)-lariciresinol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902132 (+)-lariciresinol biosynthesis|(+)-lariciresinol anabolism|(+)-lariciresinol synthesis|(+)-lariciresinol formation The chemical reactions and pathways resulting in the formation of (+)-lariciresinol. GO:1902130 (+)-lariciresinol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902130 (+)-lariciresinol metabolism The chemical reactions and pathways involving (+)-lariciresinol. GO:0098518 polynucleotide phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098518 Catalysis of the reaction: phosphopolynucleotide + H2O = polynucleotide + phosphate. CHEBI:52442 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52442 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098519 nucleotide phosphatase activity Catalysis of the reaction: nucleotide + H2O = nucleotide + phosphate. GO:0098516 detection of high humidity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098516 The series of events in which high humidity is detected and converted into a molecular signal. CHEBI:52443 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52443 GO:0098517 detection of low humidity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098517 The series of events in which low humidity is detected and converted into a molecular signal. GO:0098514 detection of high humidity stimulus involved in sensory perception biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098514 The series of events in which a high humidity stimulus is detected and converted into a molecular signal as a part of the sensory detection of high humidity. GO:0001569 branching involved in blood vessel morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001569 patterning of blood vessels The process of coordinated growth and sprouting of blood vessels giving rise to the organized vascular system. GO:0098515 detection of low humidity stimulus involved in sensory perception biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098515 The series of events in which a low humidity stimulus is detected and converted into a molecular signal as a part of the sensory detection of low humidity. GO:0098512 detection of humidity stimulus involved in sensory perception biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098512 The series of events in which a humidity stimulus is received and converted into a molecular signal as part of the sensory perception of humidity. GO:0098513 detection of humidity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098513 The series of events in which a humidity stimulus is received and converted into a molecular signal. CHEBI:52440 cephalosporin carboxylic acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52440 CHEBI:76409 (2E,11Z,14Z)-icosatrienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76409 CHEBI:76408 (3R,11Z,14Z)-3-hydroxyicosadienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76408 OPL:0000033 trypomastigote stage biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OPL_0000033 A parasite lifecycle stage of trypanosomes. In trypomastigote stage, the kinetoplast is near the posterior end of the body, and the flagellum lies attached to the cell body for most of its length by an undulating membrane. PO:0009066 anther biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009066 半葯,花粉のう (Japanese, exact)|Poaceae anther (narrow)|antera (Spanish, exact)|Zea anther (narrow) A collective plant organ structure (PO:0025007) that is the pollen-bearing part of a stamen (PO:0009029). PO:0009060 calyx biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009060 cálix (Spanish, exact)|calyces (exact, plural)|がく (Japanese, exact) A collective phyllome structure (PO:0025023) that is composed of one or more sepals (PO:0009031), and comprises the outer whorl of non-reproductive floral organs (PO:0025395). PO:0009061 androecium biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009061 androecium of upper floret of pedicellate spikelet of tassel (exact)|androecium column (narrow)|androecia (exact, plural)|Poaceae androecium (narrow)|androecium of tassel floret (exact)|androecium of lower floret of sessile spikelet of ear (narrow)|androecium of upper floret of sessile spikelet of ear (narrow)|雄蕊群 (Japanese, exact)|androecium of lower floret of pedicellate spikelet of ear (narrow)|androecium of upper floret of pedicellate spikelet of ear (narrow)|androecium of upper floret of sessile spikelet of tassel (narrow)|androecio (Spanish, exact)|Zea androecium (narrow)|androecium of ear floret (narrow)|androecium of lower floret of sessile spikelet of tassel (narrow) A collective phyllome structure (PO:0025023) composed all of the stamens (PO:0009029) in a flower (PO:0009046). PO:0009062 gynoecium biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009062 apocarpous gynoecium (narrow)|Zea gynoecium (narrow)|ginoecio (Spanish, exact)|gynoecia (exact, plural)|gynoecium of tassel floret (narrow)|pistil (broad)|雌蕊群 (Japanese, exact)|gynoecium of lower floret of sessile spikelet of ear (narrow)|gynoecium of upper floret of sessile spikelet of ear (narrow)|gynoecium of upper floret of pedicellate spikelet of tassel (narrow)|gynoecium of lower floret of pedicellate spikelet of tassel (narrow)|gynoecium of lower floret of pedicellate spikelet of ear (narrow)|gynoecium of upper floret of pedicellate spikelet of ear (narrow)|Poaceae gynoecium (narrow)|syncarpous gynoecium (narrow)|gynoecium of upper floret of sessile spikelet of tassel (narrow)|gynaecium (exact)|gynoecium of lower floret of sessile spikelet of tassel (narrow)|gynoecium of ear floret (narrow) A collective phyllome structure (PO:0025023) composed all of the carpels (PO:0009030) in a flower (PO:0009046). PO:0009067 filament biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009067 filamento (Spanish, exact)|Zea filament (narrow)|花糸 (Japanese, exact)|Poaceae filament (narrow) A stalk (PO:0025066) that is part of a stamen (PO:0009029). CHEBI:76416 (2E,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76416 CHEBI:76417 (3R,9Z,12Z,15Z,18Z)-3-hydroxytetracosatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76417 CHEBI:76414 propellant biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76414 CHEBI:76415 (3R,7Z,10Z,13Z,16Z)-3-hydroxydocosatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76415 CHEBI:76418 (2E,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76418 CHEBI:76419 (11Z,14Z,17Z,20Z)-3-oxohexacosatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76419 PO:0009055 bract biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009055 苞葉 (Japanese, exact)|scale (narrow)|bractlet (related)|bráctea (Spanish, exact)|hypsophyll (related)|bracteole (related) A phyllome that subtends a reproductive structure. CHEBI:76412 (2E,8Z,11Z,14Z)-icosatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76412 CHEBI:76413 greenhouse gas biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76413 PO:0009058 perianth biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009058 calyptra perianth (narrow)|connate perianth (related)|花蓋、花被 (Japanese, exact)|perianto (Spanish, exact)|adnate perianth (narrow) A collective phyllome structure (PO:0025023) that includes as parts the corolla (PO:0009059) and/or the calyx (PO:0009060); or one or more tepals (PO:0009033). CHEBI:76410 (11Z,14Z)-icosadienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76410 PO:0009059 corolla biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009059 corollas (exact, plural)|corola (Spanish, exact)|corollae (exact, plural)|花冠 (Japanese, exact) A collective phyllome structure (PO:0025023) that is composed of one or more petals (PO:0009032), comprising the inner whorl of non-reproductive floral organs (PO:0025395) and surrounds the androecium (PO:0009061) and the gynoecium (PO:0009062). CHEBI:76411 (3R,8Z,11Z,14Z)-3-hydroxyicosatrienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76411 CHEBI:76427 trans-2-dodecenedioyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76427 CHEBI:76428 (2E,13Z,16Z,19Z,22Z)-octacosapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76428 CHEBI:76425 (S)-3-hydroxyoctanedioyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76425 CHEBI:76426 3-oxooctanedioyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76426 CHEBI:76429 (S)-3-hydroxydodecanedioyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76429 OPL:0000015 Phlebotominae proboscis biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OPL_0000015 A proboscis that is a part of or originated from a sand fly of genus Phlebotominae. PO:0009049 inflorescence biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009049 花序 (Japanese, exact)|Triticeae spike (narrow)|inflorescencia (Spanish, exact) A reproductive shoot system (PO:0025082) that has as parts all of the shoot axes (PO:0025029) and flowers (PO:0009046; must have two or more) distal to the most distal leaf (PO:0009025). CHEBI:76420 (3R,11Z,14Z,17Z,20Z)-3-hydroxyhexacosatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76420 CHEBI:76423 trans-2-octenedioyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76423 PO:0009046 flower biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009046 basal flower (narrow)|monoclinous flower (narrow)|Asteraceae floret (narrow)|花 (Japanese, exact)|hermaphrodite flower (narrow)|double flower (narrow)|flor (Spanish, exact)|perfect flower (narrow)|floret (related) A determinate reproductive shoot system (PO:0025082) that has as part at least one carpel (PO:0009030) or at least one stamen (PO:0009029) and does not contain any other determinate shoot system (PO:0009006) as a part. CHEBI:76424 quercetin O-glycoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76424 CHEBI:76421 (2E,11Z,14Z,17Z,20Z)-hexacosapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76421 CHEBI:76422 (3R,13Z,16Z,19Z,22Z)-3-hydroxyoctacosatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76422 CHEBI:76438 (2E,21Z,24Z,27Z,30Z)-hexatriacontapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76438 CHEBI:76439 3-oxododecanedioyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76439 UBERON:0010190 pair of dorsal aortae biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010190 paired dorsal aortae the paired arterial structures of the embryo that supplies each developing somite via efferent segmental arteries; the dorsal aortae articulate with the umbilical arteries, which return mixed blood to the villi of the chorion for reoxygenation CHEBI:76436 (2E,19Z,22Z,25Z,28Z)-tetratriacontapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76436 CHEBI:76437 (3R,21Z,24Z,27Z,30Z)-3-hydroxyhexatriacontatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76437 UBERON:0010191 aortic system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010191 UBERON:0010192 genital artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010192 gonadal artery One of the laterally paired arteries that supply the gonads. UBERON:0010199 bona-fide anatomical boundary biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010199 An anatomical boundary that corresponds to some physical discontinuity. PO:0009030 carpel biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009030 心皮 (Japanese, exact)|pistil (broad)|Zea carpel (narrow)|carpelo (Spanish, exact)|Poaceae carpel (narrow) A megasporophyll, almost always at the center of a flower, its margins more or less fused together or with other carpels to enclose the ovule(s). OPL:0000006 metacyclic promastigote stage biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OPL_0000006 A promastigote stage of some kinetoplastids. PO:0009031 sepal biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009031 がく片 (Japanese, exact)|sépalo (Spanish, exact) A phyllome (PO:0006001) that is usually green, and is part of the calyx (PO:0009060). OPL:0000004 Triatominae hindgut biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OPL_0000004 A hindgut that is a part of or originated from a Triatominae bug. PO:0009032 petal biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009032 pétalo (Spanish, exact)|花弁 (Japanese, exact) A phyllome (PO:0006001) that is part of the corolla (PO:0009059), and is usually colored (not green). CHEBI:76430 (3R,15Z,18Z,21Z,24Z)-3-hydroxytriacontatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76430 CHEBI:76431 (2E,15Z,18Z,21Z,24Z)-triacontapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76431 CHEBI:76434 (2E,17Z,20Z,23Z,26Z)-dotriacontapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76434 CHEBI:76435 (3R,19Z,22Z,25Z,28Z)-3-hydroxytetratriacontatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76435 PO:0009035 nectary biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009035 蜜腺 (Japanese, exact)|nectario (Spanish, exact) A portion of secretory tissue (PO:0005656) which is a multicellular glandular structure secreting a liquid containing organic substances, including sugars. CHEBI:76432 (3R,17Z,20Z,23Z,26Z)-3-hydroxydotriacontatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76432 GO:1990673 intrinsic component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990673 intrinsic component of endoplasmic reticulum-Golgi intermediate compartment membrane The component of the ERGIC membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. CHEBI:76449 (6Z,9Z,12Z,15Z,18Z)-3-oxotetracosapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76449 GO:0050500 1,3-beta-galactosyl-N-acetylhexosamine phosphorylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050500 RHEA:20285|MetaCyc:2.4.1.211-RXN|EC:2.4.1.211 beta-D-galactopyranosyl-(1->3)-N-acetyl-D-hexosamine:phosphate galactosyltransferase activity|beta-1,3-galactosyl-N-acetylhexosamine phosphorylase activity|beta-D-galactopyranosyl-(1,3)-N-acetyl-D-hexosamine:phosphate galactosyltransferase activity Catalysis of the reaction: phosphate + beta-D-galactopyranosyl-(1->3)-N-acetyl-D-glucosamine = N-acetyl-D-glucosamine + alpha-D-galactopyranose 1-phosphate. GO:1990674 Golgi cis cisterna membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990674 cis-Golgi cisterna membrane The lipid bilayer surrounding any of the thin, flattened compartments that form the cis portion of the Golgi complex. GO:1990675 Golgi medial cisterna membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990675 medial-Golgi cisterna membrane The lipid bilayer surrounding any of the thin, flattened compartments that form the medial portion of the Golgi complex. CHEBI:76447 (2E,6Z,9Z,12Z,15Z,18Z)-tetracosahexaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76447 CHEBI:76448 (3S,6Z,9Z,12Z,15Z,18Z)-3-hydroxytetracosapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76448 GO:1990676 Golgi trans cisterna membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990676 trans-Golgi cisterna membrane The lipid bilayer surrounding any of the thin, flattened compartments that form the trans portion of the Golgi complex. GO:0050503 trehalose 6-phosphate phosphorylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050503 RHEA:20864|MetaCyc:2.4.1.216-RXN|EC:2.4.1.216 trehalose 6-phosphate:phosphate beta-D-glucosyltransferase activity Catalysis of the reaction: trehalose 6-phosphate + phosphate = glucose 6-phosphate + beta-D-glucose 1-phosphate. GO:0050504 mannosyl-3-phosphoglycerate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050504 RHEA:13537|KEGG_REACTION:R05768|MetaCyc:2.4.1.217-RXN|EC:2.4.1.217 GDP-mannose:3-phosphoglycerate 3-alpha-D-mannosyltransferase activity|MPG synthase activity Catalysis of the reaction: 3-phospho-D-glycerate + GDP-alpha-D-mannose = 2-(alpha-D-mannosyl)-3-phosphoglycerate + GDP + H(+). GO:1990670 vesicle fusion with Golgi cis cisterna membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990670 The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi cis cisterna. This can involve anterograde or retrograde transport vesicles. GO:0050501 hyaluronan synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050501 RHEA:12528|Reactome:R-HSA-2160851|MetaCyc:2.4.1.212-RXN|EC:2.4.1.212 seHAS|alternating UDP-alpha-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1,3)-[nascent hyaluronan] 4-N-acetyl-beta-D-glucosaminyltransferase and UDP-alpha-D-glucuronate:N-acetyl-beta-D-glucosaminyl-(1,4)-[nascent hyaluronan] 3-beta-D-glucuronosyltransferase activity|alternating UDP-alpha-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1->3)-[nascent hyaluronan] 4-N-acetyl-beta-D-glucosaminyltransferase and UDP-alpha-D-glucuronate:N-acetyl-beta-D-glucosaminyl-(1->4)-[nascent hyaluronan] 3-beta-D-glucuronosyltransferase activity|spHAS|HAS activity Catalysis of the reaction: UDP-D-glucuronate + UDP-N-acetyl-D-glucosamine = [beta-N-acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)](n) + 2n UDP. GO:1990671 vesicle fusion with Golgi medial cisterna membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990671 The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi medial cisterna. This can involve anterograde or retrograde transport vesicles. GO:1990672 medial-Golgi-derived vesicle fusion with Golgi trans cisterna membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990672 The joining of the lipid bilayer membrane around a medial-Golgi-derived vesicle to the lipid bilayer membrane around the Golgi trans cisterna. Vesicles are involved in anterograde transport. GO:0050502 cis-zeatin O-beta-D-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050502 RHEA:20681|EC:2.4.1.215|KEGG_REACTION:R07260|MetaCyc:RXN-4735 UDPglucose:cis-zeatin O-beta-D-glucosyltransferase activity|cis-zeatin O-b-D-glucosyltransferase activity|UDP-glucose:cis-zeatin O-beta-D-glucosyltransferase activity Catalysis of the reaction: cis-zeatin + UDP-D-glucose = O-beta-D-glucosyl-cis-zeatin + H(+) + UDP. GO:0050507 indoxyl-UDPG glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050507 RHEA:12004|KEGG_REACTION:R06048|MetaCyc:2.4.1.220-RXN|EC:2.4.1.220 indoxyl-UDPG-glucosyltransferase activity|UDP-glucose:indoxyl 3-O-beta-D-glucosyltransferase activity Catalysis of the reaction: indoxyl + UDP-D-glucose = H(+) + indican + UDP. GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050508 Reactome:R-HSA-3656254|Reactome:R-HSA-3656261|MetaCyc:2.4.1.224-RXN|Reactome:R-HSA-9036290|RHEA:16213|EC:2.4.1.224|Reactome:R-HSA-2022851|Reactome:R-HSA-2022919|Reactome:R-HSA-9036283 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-a-N-acetylglucosaminyltransferase activity|alpha-N-acetylglucosaminyltransferase II activity|UDP-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity|glucuronyl-N-acetylglucosaminylproteoglycan alpha-1,4-N-acetylglucosaminyltransferase activity Catalysis of the reaction: beta-D-glucuronosyl-(1,4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan + UDP-N-acetyl-D-glucosamine = N-acetyl-alpha-D-glucosaminyl-(1,4)-beta-D-glucuronosyl-(1,4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan + UDP. GO:0050505 hydroquinone glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050505 MetaCyc:2.4.1.218-RXN|KEGG_REACTION:R05769|EC:2.4.1.218|RHEA:12560 UDP-glucose:hydroquinone-O-beta-D-glucosyltransferase activity|arbutin synthase activity|UDPglucose:hydroquinone-O-beta-D-glucosyltransferase activity|hydroquinone:O-glucosyltransferase activity Catalysis of the reaction: hydroquinone + UDP-D-glucose = H(+) + hydroquinone O-beta-D-glucopyranoside + UDP. GO:0050506 vomilenine glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050506 MetaCyc:2.4.1.219-RXN|EC:2.4.1.219|KEGG_REACTION:R05882|RHEA:19385 UDPG:vomilenine 21-beta-D-glucosyltransferase activity|UDP-glucose:vomilenine 21-O-beta-D-glucosyltransferase activity|UDPG:vomilenine 21beta-D-glucosyltransferase activity|vomilenine-glucosyltransferase activity Catalysis of the reaction: UDP-D-glucose + vomilenine = H(+) + raucaffricine + UDP. GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050509 MetaCyc:2.4.1.225-RXN|Reactome:R-HSA-2076392|EC:2.4.1.225|Reactome:R-HSA-2022856|Reactome:R-HSA-9036289|Reactome:R-HSA-9036285|RHEA:20908|Reactome:R-HSA-3656267|Reactome:R-HSA-3656257 N-acetylglucosaminyl-proteoglycan 4-b-glucuronosyltransferase activity|heparan glucuronyltransferase II activity|N-acetylglucosaminylproteoglycan beta-1,4-glucuronyltransferase activity|UDP-alpha-D-glucuronate:N-acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-proteoglycan 4-beta-glucuronosyltransferase activity Catalysis of the reaction: N-acetyl-alpha-D-glucosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP-alpha-D-glucuronate = beta-D-glucuronosyl-(1,4)-N-acetyl-alpha-D-glucosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP. CL:0000287 eye photoreceptor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000287 CHEBI:76441 (2E,23Z,26Z,29Z,32Z)-octatriacontapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76441 CHEBI:76442 (23Z,26Z,29Z,32Z)-octatriacontatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76442 CHEBI:76440 (3R,23Z,26Z,29Z,32Z)-3-hydroxyoctatriacontatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76440 GO:1990677 mitochondrial inner membrane assembly complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990677 mitochondrion inner membrane assembly complex|INAC complex|inner membrane assembly complex A protein complex that promotes the biogenesis of mitochondrial F1Fo-ATP synthase by facilitating assembly of the peripheral stalk. Loss of INAC function causes dissociation of the F1-domain from the membrane-integral Fo-portion. CHEBI:76445 3-oxodecanedioyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76445 GO:1990678 histone H4-K16 deacetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990678 The modification of histone H4 by the removal of an acetyl group from lysine at position 16 of the histone. CHEBI:76446 (3S,6Z,9Z,12Z,15Z,18Z,21Z)-3-hydroxytetracosahexaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76446 GO:1990679 histone H4-K12 deacetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990679 The modification of histone H4 by the removal of an acetyl group from lysine at position 12 of the histone. CHEBI:76443 trans-2-decenedioyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76443 CHEBI:76444 (S)-3-hydroxydecanedioyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76444 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050510 MetaCyc:2.4.1.226-RXN|Reactome:R-HSA-3595178|Reactome:R-HSA-9632034|EC:2.4.1.226|Reactome:R-HSA-1971491 chondroitin glucuronyltransferase II activity|alpha-D-glucuronate:N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-glucuronosyl-proteoglycan 3-beta-glucuronosyltransferase activity|N-acetylgalactosaminyl-proteoglycan 3-b-glucuronosyltransferase activity Catalysis of the reaction: N-acetyl-beta-D-galactosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP-alpha-D-glucuronate = beta-D-glucuronosyl-(1,3)-N-acetyl-beta-D-galactosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP. GO:1990684 protein-lipid-RNA complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990684 miRNA-lipoprotein complex A macromolecular complex containing separate protein, lipid and RNA molecules. Separate in this context means not covalently bound to each other. GO:0050511 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050511 RHEA:23192|MetaCyc:RXN-8976|EC:2.4.1.227 undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase activity|MurG transferase activity|UDP-N-acetyl-D-glucosamine:N-acetyl-alpha-D-muramyl(oyl-L-Ala- gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol beta-1,4-N-acetylglucosaminlytransferase activity|undecaprenyldiphospho-muramoylpentapeptide b-N-acetylglucosaminyltransferase activity|UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase activity Catalysis of the reaction: Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol + UDP-N-acetyl-D-glucosamine = GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol + UDP. GO:1990685 HDL-containing protein-lipid-RNA complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990685 A protein-lipid-RNA complex containing separate high-density lipoprotein (HDL), lipid and RNA molecules. Separate in this context means not covalently bound to each other. GO:1990686 LDL-containing protein-lipid-RNA complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990686 A protein-lipid-RNA complex containing separate low-density lipoprotein (LDL), lipid and RNA molecules. Separate in this context means not covalently bound to each other. CHEBI:76458 (2E,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76458 CHEBI:76459 (R)-3-hydroxybehenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76459 GO:1990687 endoplasmic reticulum-derived vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990687 ER-derived vesicle fusion with ERGIC membrane|ER-derived vesicle fusion with ER-Golgi intermediate compartment membrane The joining of the lipid bilayer membrane around an endoplasmic reticulum-derived vesicle to the lipid bilayer membrane of the ERGIC. Such vesicles include COPII-coated transport vesicles involved in anterograde transport. GO:1990680 response to melanocyte-stimulating hormone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990680 response to MSH Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a melanocyte-stimulating hormone stimulus. The binding of any one of three melanocyte-stimulating hormones causes dispersal of melanosomes in melanophores of poikilothermic vertebrates. GO:0050514 homospermidine synthase (spermidine-specific) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050514 MetaCyc:2.5.1.45-RXN|EC:2.5.1.45|RHEA:11236 spermidine:putrescine 4-aminobutyltransferase (propane-1,3-diamine-forming) Catalysis of the reaction: spermidine + putrescine = sym-homospermidine + propane-1,3-diamine. GO:0050515 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050515 MetaCyc:2.7.1.148-RXN|KEGG_REACTION:R05634|RHEA:18437|EC:2.7.1.148 4-diphosphocytidyl-2C-methyl-D-erythritol kinase activity|4-diphosphocytidyl-2-C-methyl-D-erythritol kinase activity|CMK activity|ATP:4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol 2-phosphotransferase activity|CDP-ME kinase activity Catalysis of the reaction: 4-CDP-2-C-methyl-D-erythritol + ATP = 4-CDP-2-C-methyl-D-erythritol 2-phosphate + ADP + 2 H(+). GO:1990681 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990681 GO:0050512 lactosylceramide 4-alpha-galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050512 RHEA:11924|MetaCyc:2.4.1.228-RXN|EC:2.4.1.228 UDP-galactose:lactosylceramide 4II-alpha-D-galactosyltransferase activity|histo-blood group Pk UDP-galactose|lactosylceramide 4-a-galactosyltransferase activity|histo-blood group P(k) UDP-galactose activity|Gal-beta-1,4-Glc-beta-1-Cer alpha-1,4-galactosyltransferase activity|Gal-beta-(1,4)-Glc-beta-1-Cer alpha-(1,4)-galactosyltransferase activity|globotriaosylceramide/CD77 synthase activity Catalysis of the reaction: beta-D-galactosyl-(1,4)-D-glucosylceramide + UDP-galactose = alpha-D-galactosyl-(1,4)-beta-D-galactosyl-(1,4)-D-glucosylceramide + UDP. GO:1990682 CSF1-CSF1R complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990682 CSF1:C-FMS complex|macrophage colony-stimulating factor:receptor complex|M-CSF:C-FMS complex|M-CSF:FMS complex|M-CSF:CSF1R complex A protein complex consisting of a macrophage colony-stimulating factor (CSF1, also called M-CSF) dimer bound to a dimerized receptor (CSF1R, also called FMS). Receptor dimerization requires the presence of the ligand. GO:1990683 DNA double-strand break attachment to nuclear envelope biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990683 A process in which the DNA double-strand breaks are attached to the inner surface of the nuclear envelope proximal to the spindle pole body, or iMTOCs. GO:0050513 glycoprotein 2-beta-D-xylosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050513 EC:2.4.2.38|RHEA:10612|KEGG_REACTION:R06016|MetaCyc:2.4.2.38-RXN glycoprotein 2-b-D-xylosyltransferase activity|1,2-beta-xylosyltransferase activity|beta-1,2-xylosyltransferase activity Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + UDP-alpha-D-xylose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-[beta-D-xylosyl-(1->2)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + H(+) + UDP. GO:0050518 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050518 EC:2.7.7.60|MetaCyc:2.7.7.60-RXN|RHEA:13429|KEGG_REACTION:R05633 MEP cytidylyltransferase activity|MCT activity|CTP:2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity|4-diphosphocytidyl-2-C-methyl-D-erythritol synthase activity|4-diphosphocytidyl-2C-methyl-D-erythritol synthase activity Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + CTP = 4-CDP-2-C-methyl-D-erythritol + diphosphate. GO:0050519 holo-citrate lyase synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050519 EC:2.7.7.61|MetaCyc:2.7.7.61-RXN|RHEA:16333 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo-citrate lyase adenylyltransferase activity|2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase activity|2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo-citrate lyase activity|CitX|holo-ACP synthase activity Catalysis of the reaction: apo-citrate lyase + 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA = diphosphate + holo-citrate lyase. GO:0050516 obsolete inositol polyphosphate multikinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050516 EC:2.7.1.151|MetaCyc:2.7.1.151-RXN IP3/IP4 dual-specificity 6-/3-kinase activity|inositol-polyphosphate multikinase activity|AtIpk2beta|IP3/IP4 6-/3-kinase activity|ArgRIII|AtIpk2-alpha activity|IpmK|inositol polyphosphate multikinase activity|ATP:1D-myo-inositol-1,4,5-trisphosphate 6-phosphotransferase activity|IpK2 activity|AtIpk2-beta activity|AtIpk2alpha|inositol polyphosphate 6-/3-/5-kinase activity OBSOLETE. Catalysis of the reactions: ATP + 1D-myo-inositol 1,4,5-trisphosphate = ADP + 1D-myo-inositol 1,4,5,6-tetrakisphosphate, and ATP + 1D-myo-inositol 1,4,5,6-tetrakisphosphate = ADP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate. GO:0050517 obsolete inositol hexakisphosphate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050517 EC:2.7.4.21|MetaCyc:2.7.1.152-RXN inositol-hexakisphosphate kinase activity|ATP:1D-myo-inositol-hexakisphosphate 5-phosphotransferase activity|ATP:1D-myo-inositol-hexakisphosphate phosphotransferase activity|inositol hexakisphosphate kinase activity OBSOLETE. Catalysis of the reactions: ATP + 1D-myo-inositol hexakisphosphate = ADP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate, and ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + diphospho-1D-myo-inositol tetrakisphosphate (isomeric configuration unknown). CL:0000295 somatotropin secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000295 somatotrophin secreting cell|growth hormone secreting cell A peptide hormone secreting cell that produces growth hormone, somatotropin. CHEBI:76452 dialuric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76452 CHEBI:76453 (R)-3-hydroxyicosanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76453 CHEBI:76450 (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76450 GO:1990688 Golgi vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990688 Golgi vesicle fusion with ER-Golgi intermediate compartment membrane|Golgi vesicle fusion with ERGIC membrane The joining of the lipid bilayer membrane around a Golgi vesicle to the lipid bilayer membrane of the ERGIC. Such vesicles include COPI-coated transport vesicles involved in retrograde transport. CHEBI:76456 (2E,11Z,14Z,17Z)-icosatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76456 GO:1990689 endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with Golgi cis cisterna membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990689 ERGIC-derived vesicle fusion with cis-Golgi cisterna membrane|ER-Golgi intermediate compartment derived vesicle fusion with cis-Golgi cisterna membrane|endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with cis-Golgi cisterna membrane|ERGIC-derived vesicle fusion with Golgi cis cisterna membrane|ER-Golgi intermediate compartment derived vesicle fusion with Golgi cis cisterna membrane The joining of the lipid bilayer membrane around an ERGIC-derived vesicle to the lipid bilayer membrane around the Golgi cis cisterna. Such vesicles include COPII-coated transport vesicles involved in anterograde transport. CHEBI:76457 (3R,8Z,11Z,14Z,17Z)-3-hydroxyicosatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76457 CHEBI:76454 (R)-3-hydroxystearoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76454 CHEBI:76455 (3R,11Z,14Z,17Z)-3-hydroxyicosatrienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76455 GO:1990695 intrinsic component of Golgi trans cisterna membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990695 intrinsic component of trans-Golgi cisterna membrane The component of the Golgi trans cisterna membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0050521 alpha-glucan, water dikinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050521 MetaCyc:2.7.9.4-RXN|EC:2.7.9.4|RHEA:11668 starch-related R1 protein activity|alpha-glucan,water dikinase activity|a-glucan, water dikinase activity|ATP:alpha-glucan, water phosphotransferase activity|GWD Catalysis of the reaction: ATP + alpha-glucan + H2O = AMP + phospho-alpha-glucan + phosphate. GO:1990696 USH2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990696 USH2 quaternary protein complex A protein complex composed of four proteins, loss of which results in Usher Syndrome type 2 (USH2 syndrome), a leading genetic cause of combined hearing and vision loss. This complex is conserved in many species; in mice, it is composed of USH2A, GPR98 (aka ADGRV1), WHRN, and PDZD7. GO:0050522 oxidoreductase activity, acting on phosphorus or arsenic in donors, with other known acceptors biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050522 EC:1.20.98.- Catalysis of an oxidation-reduction (redox) reaction in which phosphorus or arsenic acts as a hydrogen or electron donor and reduces a known acceptor other than disulfide, NAD or NADP. GO:1990697 protein depalmitoleylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990697 The removal of palmitoleyl group, a 16-carbon monounsaturated fatty acid (C16:1), from a lipoprotein. CHEBI:76469 (2E,13Z,16Z,19Z,22Z,25Z)-octacosahexaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76469 GO:1990698 palmitoleoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990698 Catalysis of the transfer of a palmitoleyl group, a 16-carbon monounsaturated fatty acid (C16:1), to an acceptor molecule. GO:0050520 phosphatidylcholine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050520 RHEA:14597|KEGG_REACTION:R05794|EC:2.7.8.24|MetaCyc:2.7.8.24-RXN CDP-diacylglycerol:choline O-phosphatidyltransferase activity|CDP-diglyceride-choline O-phosphatidyltransferase activity|CDPdiglyceride-choline O-phosphatidyltransferase activity|PC synthase activity Catalysis of the reaction: CDP-diacylglycerol + choline = 1,2-diacyl-sn-glycero-3-phosphocholine + CMP + H(+). GO:1990691 cis-Golgi-derived vesicle fusion with Golgi medial cisterna membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990691 cis-Golgi-derived vesicle fusion with medial-Golgi cisterna membrane The joining of the lipid bilayer membrane around a cis-Golgi-derived vesicle to the lipid bilayer membrane around the medial-Golgi cisterna. Vesicles are involved in anterograde transport. GO:0050525 cutinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050525 EC:3.1.1.74|MetaCyc:3.1.1.74-RXN cutin hydrolase activity Catalysis of the reaction: cutin + H2O = cutin monomers. GO:0050526 poly(3-hydroxybutyrate) depolymerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050526 EC:3.1.1.75|RHEA:11248|MetaCyc:3.1.1.75-RXN PHB depolymerase activity|poly((R)-hydroxyalkanoic acid) depolymerase activity|poly(HA(SCL)) depolymerase activity|poly[(R)-hydroxyalkanoic acid] depolymerase|poly[(R)-3-hydroxybutyrate] hydrolase activity|poly(HASCL) depolymerase activity|poly(3HB) depolymerase activity|poly(HA) depolymerase activity Catalysis of the reaction: H2O + poly[(R)-3-hydroxybutanoate](n) = poly[(R)-3-hydroxybutanoate](x) + poly[(R)-3-hydroxybutanoate](n-x); x is 1-5. GO:1990692 trans-Golgi-derived vesicle fusion with Golgi medial cisterna membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990692 trans-Golgi-derived vesicle fusion with medial-Golgi cisterna membrane The joining of the lipid bilayer membrane around a trans-Golgi-derived vesicle to the lipid bilayer membrane around the medial-Golgi cisterna. Such vesicles include COPI-coated transport vesicles involved in retrograde transport. GO:0050523 obsolete oxidoreductase activity, acting on phosphorus or arsenic in donors, with other acceptors biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050523 oxidoreductase activity, acting on phosphorus or arsenic in donors, with other acceptors OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which phosphorus or arsenic acts as a hydrogen or electron donor and reduces an acceptor other than disulfide, NAD or NADP. GO:1990693 intrinsic component of Golgi cis cisterna membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990693 intrinsic component of cis-Golgi cisterna membrane The component of the Golgi cis cisterna membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0050524 coenzyme-B sulfoethylthiotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050524 UM-BBD_reactionID:r0356|RHEA:12532|EC:2.8.4.1|KEGG_REACTION:R04541|MetaCyc:METHYL-COM-HTP-RXN 2-(methylthio)ethanesulfonate:N-(7-thioheptanoyl)-3-O-phosphothreonine S-(2-sulfoethyl)thiotransferase activity|methyl-CoM reductase activity|coenzyme-B sulphoethylthiotransferase activity|methyl coenzyme M reductase activity|methyl-coenzyme-M reductase activity Catalysis of the reaction: coenzyme B + methyl-coenzyme M = coenzyme M-coenzyme B heterodisulfide + methane. Methyl-CoM is also known as 2-(methylthio)ethanesulfonate, coenzyme B as N-(7-mercaptoheptanoyl)threonine 3-O-phosphate, and coenzyme M-coenzyme B heterodisulfide as CoM-S-S-CoB. GO:1990694 intrinsic component of Golgi medial cisterna membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990694 intrinsic component of medial-Golgi cisterna membrane The component of the Golgi medial cisterna membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0050529 polyneuridine-aldehyde esterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050529 EC:3.1.1.78|KEGG_REACTION:R05825|RHEA:17501|MetaCyc:3.1.1.78-RXN PNAE activity|polyneuridine aldehyde esterase activity|polyneuridine aldehyde hydrolase (decarboxylating) Catalysis of the reaction: H(2)O + polyneuridine aldehyde = 16-epivellosimine + CO(2) + methanol. GO:0050527 poly(3-hydroxyoctanoate) depolymerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050527 EC:3.1.1.76|MetaCyc:3.1.1.76-RXN poly(3HO) depolymerase activity|poly((R)-3-hydroxyoctanoate) hydrolase activity|poly((R)-hydroxyalkanoic acid) depolymerase activity|poly[(R)-3-hydroxyoctanoate] hydrolase activity|poly(HAMCL) depolymerase activity|poly[(R)-hydroxyalkanoic acid] depolymerase|PHA depolymerase activity|poly(HA(MCL)) depolymerase activity|PHO depolymerase activity|poly(HA) depolymerase activity|poly{oxycarbonyl[(R)-2-pentylethylene]} hydrolase activity Catalysis of the reaction: H2O + poly[(R)-3-hydroxyoctanoate](n) = poly[(R)-3-hydroxyoctanoate](x) + poly[(R)-3-hydroxyoctanoate](n-x); x is 1-5. GO:1990690 Golgi medial cisterna-derived vesicle fusion with Golgi cis cisterna membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990690 medial-Golgi cisterna-derived vesicle fusion with cis-Golgi cisterna membrane The joining of the lipid bilayer membrane around a Golgi medial cisterna-derived vesicle to the lipid bilayer membrane around the Golgi cis cisterna. Such vesicles include COPI-coated transport vesicles involved in retrograde transport. GO:0050528 acyloxyacyl hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050528 EC:3.1.1.77|RHEA:12032|MetaCyc:3.1.1.77-RXN Catalysis of the reaction: 3-(acyloxy)acyl group of bacterial toxin = 3-hydroxyacyl group of bacterial toxin + a fatty acid. OPL:0000056 Trypanosoma brucei metacyclic trypomastigote stage biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OPL_0000056 A metacyclic trypomastigote stage in the lifecycle of Trypanosoma brucei that occurs either in vertebrate host bloodstream or in salivary glands of an insect vector. PO:0009088 seed coat biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009088 種子種皮 (Japanese, exact)|portion of seed coat tissue (exact)|cubierta de la semilla (Spanish, exact) A portion of plant tissue that is the covering of a seed derived from ovular - mainly integumentary - tissue. CHEBI:76460 (3R,7Z,10Z,13Z,16Z,19Z)-3-hydroxydocosapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76460 CHEBI:76463 (3R)-3-hydroxytetracosanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76463 CHEBI:76464 (2E,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76464 CHEBI:76461 (2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76461 CHEBI:76462 (3R,9Z,12Z,15Z,18Z,21Z)-3-hydroxytetracosapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76462 PO:0009089 endosperm biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009089 albumen (exact)|endosperma (Spanish, exact)|内胚乳、胚乳 (Japanese, exact) A portion of plant tissue (PO:0009007) which is a maximal portion of nutritive plant tissue in a seed (PO:0009010). GO:1990699 palmitoleyl hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990699 Catalysis of a hydrolase reaction that removes a palmitoleyl moiety, a 16-carbon monounsaturated fatty acid (C16:1), from some substrate. CHEBI:76467 (2E,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76467 CHEBI:76468 (3R,13Z,16Z,19Z,22Z,25Z)-3-hydroxyoctacosapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76468 CHEBI:76465 (R)-3-hydroxyhexacosanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76465 CHEBI:76466 (3R,11Z,14Z,17Z,20Z,23Z)-3-hydroxyhexacosapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76466 GO:0050532 2-phosphosulfolactate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050532 MetaCyc:R229-RXN|RHEA:23416|KEGG_REACTION:R05789|EC:3.1.3.71 (2R)-phosphosulfolactate phosphohydrolase activity|ComB phosphatase activity|(R)-2-phospho-3-sulfolactate phosphohydrolase activity|2-phosphosulpholactate phosphatase activity Catalysis of the reaction: (2R)-O-phospho-3-sulfolactate + H(2)O = (R)-3-sulfolactate + phosphate. GO:0050533 5-phytase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050533 MetaCyc:3.1.3.72-RXN|EC:3.1.3.72|RHEA:13001 myo-inositol-hexakisphosphate 5-phosphohydrolase activity Catalysis of the reaction: H2O + myo-inositol hexakisphosphate = phosphate + 1L-myo-inositol 1,2,3,4,6-pentakisphosphate. GO:0050530 glucosylglycerol 3-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050530 EC:3.1.3.69|RHEA:22652|KEGG_REACTION:R05791|MetaCyc:3.1.3.69-RXN StpA|2-(beta-D-glucosyl)-sn-glycerol-3-phosphate phosphohydrolase activity|salt tolerance protein A Catalysis of the reaction: 2-O-(beta-D-glucosyl)-sn-glycerol 3-phosphate + H(2)O = 2-O-(beta-D-glucosyl)-sn-glycerol + phosphate. GO:0050531 mannosyl-3-phosphoglycerate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050531 MetaCyc:3.1.3.70-RXN|RHEA:19309|EC:3.1.3.70|KEGG_REACTION:R05790 alpha-D-mannosyl-3-phosphoglycerate phosphohydrolase activity Catalysis of the reaction: 2-(alpha-D-mannosyl)-3-phosphoglycerate + H(2)O = 2-(alpha-D-mannosyl)-D-glycerate + phosphate. GO:0050536 (S)-N-acetyl-1-phenylethylamine hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050536 MetaCyc:3.5.1.85-RXN|RHEA:23952|EC:3.5.1.85|KEGG_REACTION:R07301 (S)-N-acetyl-1-phenylethylamine amidohydrolase activity|(S)-N-acetylphenylethylamine:H2O hydrolase activity Catalysis of the reaction: N-acetylphenylethylamine + H(2)O = acetate + phenylethylamine. GO:0050537 mandelamide amidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050537 MetaCyc:3.5.1.86-RXN|RHEA:22876|EC:3.5.1.86|KEGG_REACTION:R05783 Pseudomonas mandelamide hydrolase activity|mandelamide hydrolase activity Catalysis of the reaction: (R)-mandelamide + H(2)O = (R)-mandelate + NH(4)(+). GO:0050534 3-deoxyoctulosonase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050534 MetaCyc:3.2.1.144-RXN|EC:3.2.1.144 alpha-Kdo-ase activity|3-deoxyoctulosonyl-lipopolysaccharide hydrolase activity Catalysis of the reaction: 3-deoxyoctulosonyl-lipopolysaccharide + H2O = 3-deoxyoctulosonic acid + lipopolysaccharide. GO:0050535 beta-primeverosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050535 MetaCyc:3.2.1.149-RXN|EC:3.2.1.149|RHEA:24480 b-primeverosidase activity|6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranoside 6-O-(beta-D-xylosyl)-beta-D-glucohydrolase activity Catalysis of the reaction: a 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranoside + H2O = 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranose + an alcohol. GO:0050538 N-carbamoyl-L-amino-acid hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050538 RHEA:17581|MetaCyc:3.5.1.87-RXN|EC:3.5.1.87 N-carbamoyl-L-amino acid amidohydrolase activity|L-carbamoylase activity Catalysis of the reaction: N-carbamoyl-L-2-amino acid + H2O = L-2-amino acid + NH3 + CO2. The N-carbamoyl-L-2-amino acid is a 2-ureido carboxylate. GO:0050539 maleimide hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050539 EC:3.5.2.16|RHEA:24476|KEGG_REACTION:R05781|MetaCyc:3.5.2.16-RXN cyclic-imide amidohydrolase (decyclizing)|cyclic imide hydrolase activity|cyclic-imide amidohydrolase (decyclicizing)|imidase activity Catalysis of the reaction: H(2)O + maleimide = H(+) + maleamate. PO:0009074 style biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009074 花柱 (Japanese, exact)|Poaceae style (narrow)|estilo (Spanish, exact) A cardinal organ part (PO:0025001) which is an elongated part of a carpel (PO:0009030) or gynoecium (PO:0009062) between the plant ovary (PO:0009072) and the stigma (PO:0009073), and through which the pollen tube (GO:0090406) grows. OPL:0000048 Trypanosoma brucei lifecycle stage biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OPL_0000048 A lifecycle stage of Trypanosoma brucei. CHEBI:76470 (3R,15Z,18Z,21Z,24Z,27Z)-3-hydroxytriacontapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76470 PO:0009071 anther wall tapetum biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009071 Poaceae tapetum (narrow)|pollen sac tapetum (exact)|tapete (Spanish, exact)|portion of anther wall tapetal tissue (exact)|Zea tapetum (narrow)|葯壁タペート組織 (Japanese, exact) A microsporangium tapetum (PO:0025314) that is part of an anther wall (PO:0000002). CHEBI:76471 (2E,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76471 PO:0009072 plant ovary biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009072 ovario vegetal (Spanish, exact)|Zea ovary (narrow)|子房 (Japanese, exact)|Poaceae ovary (narrow) A plant structure (PO:0009011) that is the basal portion of a carpel (PO:0009030) or group of fused carpels (gynoecium; PO:0009062) and encloses the plant ovule(s) (PO:0020003). PO:0009073 stigma biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0009073 stigmata (exact, plural)|stigmas (exact, plural)|柱頭 (Japanese, exact)|estigma (Spanish, exact)|Zea stigma (narrow)|Poaceae stigma (narrow) A cardinal organ part (PO:0025001), usually apical, that is part of a carpel (PO:0009030) or group of fused carpels on which the pollen (PO:0025281) germinates. CHEBI:76474 (2E,17Z,20Z,23Z,26Z,29Z)-dotriacontahexaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76474 CHEBI:76475 (3R,19Z,22Z,25Z,28Z,31Z)-3-hydroxytetratriacontapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76475 CHEBI:76472 (R)-3-hydroxyoctacosanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76472 CHEBI:76473 (3R,17Z,20Z,23Z,26Z,29Z)-3-hydroxydotriacontapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76473 CHEBI:76478 dibutyrin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76478 CHEBI:76479 (2E,21Z,24Z,27Z,30Z,33Z)-hexatriacontahexaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76479 CHEBI:76476 (2E,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76476 CHEBI:76477 (3R,21Z,24Z,27Z,30Z,33Z)-3-hydroxyhexatriacontapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76477 CHEBI:47003 leucine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47003 CHEBI:47004 alpha-L-ribose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47004 CHEBI:47005 beta-L-ribose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47005 CHEBI:47006 D-ribopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47006 UBERON:0000457 cavernous artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000457 cavernous branch of cavernous part of internal carotid artery|ramus sinus cavernosi (pars cavernosa) (arteria carotis interna) Any of several small branches of the internal carotid artery that supply the trigeminal ganglion and the walls of the cavernous and petrosal sinuses. CHEBI:47007 ribopyranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47007 UBERON:0000458 endocervix biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000458 The region of the opening of the uterine cervix into the uterine cavity. UBERON:0000459 uterine wall biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000459 anatomical wall of uterus|uterus anatomical wall|uterus wall|wall of uterus An anatomical wall that is part of a uterus [Automatically generated definition]. CHEBI:62641 perillate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62641 CHEBI:47000 L-ribofuranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47000 CHEBI:47002 beta-D-ribose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47002 CHEBI:37677 L-mannopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37677 CHEBI:37676 L-mannose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37676 CHEBI:62643 anionic phospholipid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62643 CHEBI:62649 alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1->1')-Cer biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62649 CHEBI:37679 beta-L-mannose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37679 UBERON:0000464 anatomical space biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000464 anatomical spaces|lumen|space|lumen space Non-material anatomical entity of three dimensions, that is generated by morphogenetic or other physiologic processes; is surrounded by one or more anatomical structures; contains one or more organism substances or anatomical structures. UBERON:0000465 material anatomical entity biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000465 Anatomical entity that has mass. CHEBI:37670 protease inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37670 UBERON:0000466 immaterial anatomical entity biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000466 immaterial physical anatomical entity Anatomical entity that has no mass. UBERON:0000467 anatomical system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000467 system|anatomical systems|organ system|connected anatomical system|body system Multicellular, connected anatomical structure that has multiple organs as parts and whose parts work together to achieve some shared function. CHEBI:37673 ajmalan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37673 CHEBI:37674 17-O-acetylajmaline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37674 CHEBI:37671 (1->3)-beta-D-glucan biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37671 UBERON:0000463 organism substance biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000463 organism substance|portion of body substance|body substance|portion of organism substance|body fluid or substance Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body. CHEBI:23048 carvones biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23048 CHEBI:23045 carotenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23045 GO:0001700 embryonic development via the syncytial blastoderm biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001700 The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster. CHEBI:23046 carveol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_23046 CHEBI:62651 thia-alkylglucosinolate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62651 CHEBI:23043 epoxycarotenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23043 CHEBI:23044 carotenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23044 CHEBI:23041 carotenal biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23041 CHEBI:23042 carotene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23042 GO:0001709 cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001709 Wikipedia:Cell_fate_determination A process involved in cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment. GO:0001705 ectoderm formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001705 The formation of ectoderm during gastrulation. CHEBI:37680 alpha-L-mannose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37680 GO:0001706 endoderm formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001706 endoblast formation The formation of the endoderm during gastrulation. UBERON:0000454 cerebral subcortex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000454 cerebral medulla|subcortex The layer located below the cerebral cortex that includes the forebrain, midbrain and hindbrain. GO:0001707 mesoderm formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001707 The process that gives rise to the mesoderm. This process pertains to the initial formation of the structure from unspecified parts. UBERON:0000456 secretion of exocrine gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000456 bodily secretion|secretion|exocrine gland fluid|exocrine gland fluid or secretion|secreted substance|external secretion|exocrine gland secretion|exocrine gland fluid/secretion A portion of organism substance that is produced by exocrine glands. GO:0001708 cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001708 The process involved in the specification of cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. GO:0001701 in utero embryonic development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001701 The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus. CHEBI:37684 mannose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37684 GO:0001702 gastrulation with mouth forming second biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001702 deuterostomic gastrulation A gastrulation process in which the initial invagination becomes the anus and the mouth forms second. GO:0001703 gastrulation with mouth forming first biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001703 protostomic gastrulation A gastrulation process in which the initial invagination becomes the mouth and the anus forms second. GO:0001704 formation of primary germ layer biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001704 The formation of the ectoderm, mesoderm and endoderm during gastrulation. CHEBI:37683 mannopyranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37683 UBERON:0000439 arachnoid trabecula biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000439 trabecula arachnoideum|arachnoid trabeculae The arachnoid trabeculae are delicate strands of connective tissue that loosely connect the two innermost layers of the meninges -- the arachnoid mater and the pia mater. They are found within the subarachnoid space where cerebrospinal fluid is also found. Embryologically, the trabeculae are the remnants of the common precursor that forms both the arachnoid and pial layers of the meninges. CHEBI:23014 carbon oxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23014 CHEBI:23012 carbon disulfide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_23012 CHEBI:23018 EC 4.2.1.1 (carbonic anhydrase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23018 CHEBI:23019 carbonyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_23019 CHEBI:23016 carbonates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23016 CHEBI:62663 hydroxy-alkenylglucosinolate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62663 CHEBI:37655 D-erythronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37655 CHEBI:37653 phosphoerythronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37653 CHEBI:37654 erythronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37654 CHEBI:37659 oleanolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37659 UBERON:0000442 right testicular vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000442 right spermatic vein|vena testicularis sinistra|vena testicularis (adrenalis) dextra|vena testicularis dextra A vein that drains the left pampiniform plexus and empties into the left renal vein. UBERON:0000443 left testicular vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000443 vena testicularis sinistra|left spermatic vein|vena testicularis dextra A vein that drains the right pampiniform plexus and empties into the inferior vena cava. UBERON:0000444 lymphoid follicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000444 nodulus lymphoideus|lymphatic nodule|nodular lymphoid tissue|lymphoid nodule|nodulus lymphaticus|folliculus lymphaticus|lymphatic follicle . CHEBI:37651 pyrimidine ribonucleoside 2'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37651 UBERON:0000440 trabecula biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000440 A small, often microscopic, tissue element in the form of a small beam, strut or rod, generally having a mechanical function, and usually but not necessarily composed of dense collagenous tissue. On histological section, a trabecula can look like a septum, but in three dimensions they are topologically distinct, with trabeculae being roughly rod or pillar-shaped and septa being sheet-like. Trabeculae are usually composed of dense fibrous tissue, i.e. mainly of collagen, and in most cases provide mechanical strengthening or stiffening to a soft solid organ, such as the spleen. They can be composed of other materials, such as bone or muscle[WP]. CHEBI:37650 ribonucleoside 2'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37650 UBERON:0000428 prostate epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000428 prostate epithelial tissue|prostatic epithelium|epithelial tissue of prostate gland|epithelium of prostate gland|prostate gland epithelial tissue|epithelium of prostatic gland|prostatic gland epithelium|epithelial tissue of prostate|epithelium of prostate|prostate gland epithelium The prostate epithelium. UBERON:0000429 enteric plexus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000429 plexus nervosus entericus|intrinsic nerve plexus|plexus entericus|sympathetic enteric nerve plexus|enteric nerve plexus A plexus of autonomic nerve fibers within the wall of the digestive tube, and made up of the submucosal, myenteric, and subserosal plexuses; it contains visceral afferent fibers, sympathetic postganglionic fibers, parasympathetic preganglionic and postganglionic fibers, and parasympathetic postganglionic cell bodies. CHEBI:23022 carboxy-2-hydroxymuconate semialdehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23022 CHEBI:37667 sesquiterpene lactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37667 CHEBI:37668 terpene lactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37668 CHEBI:37669 methanopterins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37669 CHEBI:37662 aldehydo-galactose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37662 CHEBI:37661 glucopyranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37661 CHEBI:72003 3-hydroxyisoheptadecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72003 CHEBI:72004 hexadec-9-enoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72004 CHEBI:72006 (E)-isoheptadec-2-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72006 CHEBI:37639 polysaccharide phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37639 CHEBI:62682 inositol phosphomannosylinositol phosphoceramide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62682 OPL:0000232 parasite organism biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OPL_0000232 An organism living in, with, or on another organism in parasitism. Individual members of parasite species, such as Leishmania, Plasmodium, Trypanosoma, etc. are members of this class. CHEBI:37631 beta-L-glucose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37631 CHEBI:37630 alpha-L-glucose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37630 CHEBI:72000 (3E,5Z)-tetradecadienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72000 CHEBI:72001 (3E,5Z)-tetradecadienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72001 CHEBI:23003 carbamate ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23003 CHEBI:23004 carbamoyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_23004 CHEBI:23007 carbohydrate-containing antibiotic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23007 CHEBI:72019 N-octacosanoylsphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72019 CHEBI:23000 caprolactams biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23000 CHEBI:86644 Gibberellic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86644 UBERON:0000490 unilaminar epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000490 unilaminar epithelia|simple epithelium Epithelium which consists of a single layer of epithelial cells. Examples: endothelium, mesothelium, glandular squamous epithelium.[FMA] CHEBI:37645 luteolin 7-O-[(beta-D-glucosyluronic acid)-(1->2)-(beta-D-glucosiduronic acid)] 4'-O-beta-D-glucosiduronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37645 CHEBI:37642 (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37642 CHEBI:37643 (25S)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37643 CHEBI:37649 purine ribonucleoside 2'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37649 CHEBI:86649 Guanidineacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86649 CHEBI:37646 2-acyl-sn-glycero-3-phosphoserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37646 CHEBI:72010 hydroxyflavan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72010 CHEBI:37640 (24S)-7alpha,24-dihydroxycholesterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37640 UBERON:0000479 tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000479 portion of tissue|tissue portion|simple tissue Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organisation is at least partly a repetition of their short-range organisation. CHEBI:37619 L-galactopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37619 CHEBI:37617 aldehydo-L-galactose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37617 CHEBI:37618 L-galactose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37618 CHEBI:37611 cyclohexa-1,4-diene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37611 OPL:0000215 Glossina midgut biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OPL_0000215 A midgut that is a part of or originated from a tsetse fly of genus Glossina. CHEBI:37610 cyclohexa-1,3-diene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37610 UBERON:0000481 multi-tissue structure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structures Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona-fide boundaries from other distinct structural units of different types. CHEBI:37613 cyclohexadiene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37613 CHEBI:37614 alkenyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37614 UBERON:0000486 multilaminar epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000486 stratified epithelium|laminated epithelium Epithelium which consists of more than one layer of epithelial cells that may or may not be in contact with a basement membrane. Examples: keratinized stratified squamous epithelium, ciliated stratified columnar epithelium.[FMA] UBERON:0000487 simple squamous epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000487 simple squamous epithelia|epithelium simplex squamosum Unilaminar epithelium which consists of a single layer of squamous cells. Examples: pulmonary alveolar epithelium, endothelium.[FMA] UBERON:0000488 atypical epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000488 heterogenous epithelium|atypical epithelia Epithelium that consists of epithelial cells not arranged in one ore more layers. UBERON:0000489 cavitated compound organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000489 cavitated compound organs|cavitated organ Compound organ that contains one or more macroscopic anatomical spaces. UBERON:0000483 epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000483 portion of epithelium|epithelial tissue Portion of tissue, that consists of one or more layers of epithelial cells connected to each other by cell junctions and which is underlain by a basal lamina. Examples: simple squamous epithelium, glandular cuboidal epithelium, transitional epithelium, myoepithelium[CARO]. UBERON:0000484 simple cuboidal epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000484 simple cuboidal epithelia|epithelium simplex cuboideum Unilaminar epithelium that consists of a single layer of cuboidal cells. UBERON:0000485 simple columnar epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000485 columnar epithlium|simple columnar epithelia|columnar epithelium|simple columnar epithelium|epithelium simplex columnare Unilaminar epithelium, which consists of a single layer of columnar cells. Examples: ciliated columnar epithelium, gastric epithelium, microvillus columnar epithelium.[FMA] UBERON:0000468 multicellular organism biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000468 Koerper|organism|whole body|animal|body|whole organism|multi-cellular organism Anatomical structure that is an individual member of a species and consists of more than one cell. CHEBI:37622 carboxamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37622 CHEBI:37623 7alpha,25-dihydroxycholesterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37623 CHEBI:37620 beta-L-galactose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37620 OPL:0000203 Schistosoma mansoni lifecycle stage biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OPL_0000203 A lifecycle stage of Schistosoma mansoni. CHEBI:37621 galactopyranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37621 CHEBI:37627 L-glucopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37627 OPL:0000209 Leishmania major lifecycle stage biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OPL_0000209 A parasite lifecycle stage of Leishmania major. CHEBI:37624 L-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37624 UBERON:0000475 organism subdivision biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000475 body region|cardinal body part|body part|anatomic region Anatomical structure which is a subdivision of a whole organism, consisting of components of multiple anatomical systems, largely surrounded by a contiguous region of integument. UBERON:0000476 acellular anatomical structure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000476 acellular anatomical structures Anatomical structure that consists of cell parts and cell substances and together does not constitute a cell or a tissue. UBERON:0000477 anatomical cluster biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000477 Anatomical group that has its parts adjacent to one another. UBERON:0000478 extraembryonic structure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000478 extraembryonic tissue|extraembryonic structures|extra-embryonic structure A multicellular anatomical structure that is associated with an embryo and derived from the zygote from which it develops, but which does not contribute to the embryo proper or to structures that are part of the same organism after embryogenesis. UBERON:0000471 compound organ component biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000471 compound organ components Multi-tissue structure that is part of a compound organ. UBERON:0000473 testis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000473 gonad of male reproductive system|orchis|testicle|gonad of male genitalia|testiculus|testes|male gonad A gonad of a male animal. A gonad produces and releases sperm. UBERON:0000474 female reproductive system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000474 reproductive system of female organism|female genitalia|female organism genitalia|gynaecological tissue|female genital tract|female reproductive tract|genitalia of female organism|female genitals|female organism reproductive system|female genital system|systema genitale femininum The organs and associated structures associated with bearing offspring in a female animal. GO:0001774 microglial cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001774 The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. GO:0098686 hippocampal mossy fiber to CA3 synapse biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098686 One of the giant synapses that form between the mossy fiber axons of dentate gyrus granule cells and the large complex spines of CA3 pyramidal cells. It consists of a giant bouton known as the mossy fiber expansion, synapsed to the complex, multiheaded spine (thorny excresence) of a CA3 pyramidal cell. GO:0098687 chromosomal region biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098687 chromosome region Any subdivision of a chromosome along its length. GO:0001775 cell activation biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0001775 A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand. GO:0098684 photoreceptor ribbon synapse biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098684 A ribbon synapse between a retinal photoreceptor cell (rod or cone) and a retinal bipolar cell. These contain a plate-like synaptic ribbon. GO:0001776 leukocyte homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001776 leucocyte homeostasis|immune cell homeostasis The process of regulating the proliferation and elimination of cells of the immune system such that the total number of cells of a particular cell type within a whole or part of an organism is stable over time in the absence of an outside stimulus. GO:0098685 Schaffer collateral - CA1 synapse biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098685 A synapse between the Schaffer collateral axon of a CA3 pyramidal cell and a CA1 pyramidal cell. GO:0001777 T cell homeostatic proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001777 T-lymphocyte homeostatic proliferation|resting T-cell proliferation|T lymphocyte homeostatic proliferation|resting T cell proliferation|T-cell homeostatic proliferation The non-specific expansion of T cell populations within a whole or part of an organism to reach to a total number of T cells which will then remain stable over time in the absence of an external stimulus. GO:0001770 establishment of natural killer cell polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001770 NK cell polarization|establishment of NK cell polarity|natural killer cell polarization The directed orientation of natural killer cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with a cell displaying natural killer cell activating ligands. GO:0098682 arciform density biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098682 An electron dense structure that anchors a synaptic ribbon to the presynaptic membrane. GO:0098683 cochlear hair cell ribbon synapse biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098683 A ribbon synpase of an auditory hair cell of the cochlear. These ribbon synapses contain spherical synaptic ribbons and lack and arciform density. GO:0001771 immunological synapse formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001771 formation of immunological synapse The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and target cell, which facilitates activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction. GO:0098680 template-free RNA nucleotidyltransferase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098680 Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the addition of a terminal nucleotide to an RNA molecule in the absence of a nucleic acid template. GO:0001772 immunological synapse biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001772 Wikipedia:Immunological_synapse supramolecular activation cluster|c-SMAC An area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell formed through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and the target cell and facilitating activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction. GO:0001773 myeloid dendritic cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001773 The change in morphology and behavior of a dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. GO:0098681 synaptic ribbon biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098681 A non-membrane bound, electron dense structure associated that extends perpendicular to the presynaptic membrane in ribbon synapses. The ribbon's surface is studded with small particles to which synaptic vesicles tether via fine filaments. The tethered vesicles function as a pool, several fold greater than the docked pool available for fast release, which supports sustained release of vesicles. Synaptic ribbons may be plate like or spherical. GO:0060070 canonical Wnt signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060070 canonical Wnt-activated signaling pathway|Wnt receptor signaling pathway through beta-catenin|canonical Wnt receptor signaling pathway|Wnt receptor signalling pathway through beta-catenin|Wnt receptor signaling pathway via beta-catenin|frizzled-1 receptor signaling pathway The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes. GO:0060071 Wnt signaling pathway, planar cell polarity pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060071 Wnt receptor signalling pathway, planar cell polarity pathway|Wnt receptor signaling pathway, planar cell polarity pathway|Wnt-JNK signaling pathway|Wnt-activated signaling pathway, planar cell polarity pathway|non-canonical Wnt signaling pathway|planar cell polarity pathway|PCP pathway|Wnt-PCP signaling pathway The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity. GO:0060072 large conductance calcium-activated potassium channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0060072 BK calcium-activated potassium channel activity|BK channel activity|BK KCa channel activity|large conductance KCa channel activity Enables the transmembrane transfer of potassium by a channel with a unit conductance of 100 to 220 picoSiemens that opens in response to stimulus by concerted actions of internal calcium ions and membrane potential. Large conductance calcium-activated potassium channels are less sensitive to calcium than are small or intermediate conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism. GO:0060073 micturition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060073 Wikipedia:Urination urine voiding|urination The regulation of body fluids process in which parasympathetic nerves stimulate the bladder wall muscle to contract and expel urine from the body. GO:0060074 synapse maturation biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0060074 synaptic maturation The process that organizes a synapse so that it attains its fully functional state. Synaptic maturation plays a critical role in the establishment of effective synaptic connections in early development. GO:1902498 regulation of protein autoubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902498 regulation of protein self-ubiquitinylation|regulation of protein auto-ubiquitinylation|regulation of protein self-ubiquitination|regulation of protein auto-ubiquitination|regulation of protein autoubiquitinylation Any process that modulates the frequency, rate or extent of protein autoubiquitination. GO:1902499 positive regulation of protein autoubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902499 up regulation of protein autoubiquitination|upregulation of protein self-ubiquitinylation|upregulation of protein auto-ubiquitinylation|up-regulation of protein self-ubiquitination|up-regulation of protein autoubiquitinylation|activation of protein autoubiquitinylation|up-regulation of protein auto-ubiquitination|upregulation of protein autoubiquitination|up regulation of protein self-ubiquitinylation|activation of protein self-ubiquitinylation|positive regulation of protein self-ubiquitinylation|upregulation of protein self-ubiquitination|up regulation of protein auto-ubiquitinylation|activation of protein auto-ubiquitinylation|positive regulation of protein auto-ubiquitinylation|positive regulation of protein autoubiquitinylation|upregulation of protein auto-ubiquitination|up-regulation of protein autoubiquitination|up regulation of protein autoubiquitinylation|activation of protein autoubiquitination|up regulation of protein self-ubiquitination|up-regulation of protein self-ubiquitinylation|activation of protein self-ubiquitination|positive regulation of protein self-ubiquitination|up-regulation of protein auto-ubiquitinylation|up regulation of protein auto-ubiquitination|activation of protein auto-ubiquitination|upregulation of protein autoubiquitinylation|positive regulation of protein auto-ubiquitination Any process that activates or increases the frequency, rate or extent of protein autoubiquitination. GO:0060075 regulation of resting membrane potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060075 regulation of resting potential Any process that modulates the establishment or extent of a resting potential, the electrical charge across the plasma membrane, with the interior of the cell negative with respect to the exterior. The resting potential is the membrane potential of a cell that is not stimulated to be depolarized or hyperpolarized. GO:1902496 obsolete protein binding involved in negative regulation of telomere maintenance via telomerase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1902496 protein binding involved in down-regulation of telomere maintenance via telomerase activity|protein binding involved in down regulation of telomere maintenance via telomerase activity|protein binding involved in downregulation of telomere maintenance via telomerase activity|protein binding involved in inhibition of telomere maintenance via telomerase OBSOLETE. Any protein binding that is involved in negative regulation of telomere maintenance via telomerase. GO:0060076 excitatory synapse biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0060076 Wikipedia:Excitatory_synapse A synapse in which an action potential in the presynaptic cell increases the probability of an action potential occurring in the postsynaptic cell. GO:1902497 iron-sulfur cluster transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902497 iron-sulfur cluster transport A process in which an iron-sulfur cluster is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. GO:0060077 inhibitory synapse biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0060077 Wikipedia:Inhibitory_postsynaptic_potential A synapse in which an action potential in the presynaptic cell reduces the probability of an action potential occurring in the postsynaptic cell. GO:0060078 regulation of postsynaptic membrane potential biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0060078 regulation of post-synaptic membrane potential Any process that modulates the potential difference across a post-synaptic membrane. GO:0060079 excitatory postsynaptic potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060079 regulation of excitatory post-synaptic membrane potential|regulation of EPSP A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential. GO:0001778 plasma membrane repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001778 The resealing of a cell plasma membrane after cellular wounding due to, for instance, mechanical stress. GO:0001779 natural killer cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001779 NK cell differentiation|natural killer cell development The process in which a relatively unspecialized cell acquires the specialized features of a natural killer cell. GO:0098688 parallel fiber to Purkinje cell synapse biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098688 An excitatory synapse formed by the parallel fibers of granule cells synapsing onto the dendrites of Purkinje cells. GO:0098689 latency-replication decision biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098689 VZ:3964 lytic switch|prophage induction|proviral induction|reactivation of latent virus|Latency-replication switch|proviral switch The process by which a virus switches on its replication cycle in an infected cell. The process is typically controlled by a genetic swtich controlled by environmental factors such as cell type, cell shape, the availability of nutrients, superinfection or exposure of infected cells to UV or various chemical stimuli. GO:0098697 ryanodine-sensitive calcium-release channel activity involved in regulation of postsynaptic cytosolic calcium levels biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098697 Any ryanodine-sensitive calcium-release channel activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration. GO:0001785 prostaglandin J receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001785 PGJ receptor activity|PGJ(2) receptor activity Combining with prostaglandin J (PGJ(2)), a metabolite of prostaglandin D (PGD(2)) to initiate a change in cell activity. GO:0001786 phosphatidylserine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001786 Interacting selectively and non-covalently with phosphatidylserine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of L-serine. GO:0098698 postsynaptic specialization assembly biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098698 The aggregation, arrangement and bonding together of a set of components to form a postsynaptic specialization, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane. GO:0001787 natural killer cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001787 NK cell proliferation The expansion of a natural killer cell population by cell division. GO:0098695 inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098695 IP3 receptor activity involved in regulation of postsynaptic cytosolic calcium levels Any inositol 1,4,5-trisphosphate receptor activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration. GO:0001788 antibody-dependent cellular cytotoxicity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001788 Wikipedia:Antibody-dependent_cellular_cytotoxicity|Wikipedia:Antibody-dependent_cell-mediated_cytotoxicity antibody-dependent cell killing|ADCC|antibody dependent cell killing|antibody-dependent cell death|type VI hypersensitivity|antibody dependent cell death Cytolysis of target cells by natural killer cells, eosinophils, neutrophils, monocytes, or macrophages following engagement of antibodies bound to the target cells by Fc receptors on the effector cells. GO:0098696 regulation of neurotransmitter receptor localization to postsynaptic specialization membrane biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098696 Any process that modulates the frequency, rate or extent of neurotransmitter receptor localization to postsynaptic specialization membrane. GO:0001781 neutrophil apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001781 neutrophil programmed cell death by apoptosis|apoptosis of neutrophils|neutrophil apoptosis|programmed cell death, neutrophils|programmed cell death of neutrophils by apoptosis Any apoptotic process in a neutrophil, any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes. GO:0098693 regulation of synaptic vesicle cycle biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098693 Any process that modulates the frequency, rate or extent of the synaptic vesicle cycle. GO:0001782 B cell homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001782 B lymphocyte homeostasis|B-cell homeostasis|B-lymphocyte homeostasis The process of regulating the proliferation and elimination of B cells such that the total number of B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. GO:0098694 regulation of synaptic vesicle budding from presynaptic endocytic zone membrane biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098694 Any process that modulates the frequency, rate or extent of synaptic vesicle budding from presynaptic endocytic zone membrane. GO:0001783 B cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001783 apoptosis of B-lymphocytes|B lymphocyte apoptosis|B-cell programmed cell death by apoptosis|programmed cell death of B cells by apoptosis|apoptosis of B-cells|programmed cell death of B lymphocytes by apoptosis|programmed cell death, B-lymphocytes|programmed cell death, B-cells|B-cell apoptosis|B lymphocyte programmed cell death by apoptosis|apoptosis of B lymphocytes|B cell programmed cell death by apoptosis|B-lymphocyte apoptosis|programmed cell death of B-cells by apoptosis|apoptosis of B cells|B cell apoptosis|programmed cell death of B-lymphocytes by apoptosis|programmed cell death, B lymphocytes|B-lymphocyte programmed cell death by apoptosis|programmed cell death, B cells Any apoptotic process in a B cell, a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity. GO:0098691 dopaminergic synapse biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098691 A synapse that uses dopamine as a neurotransmitter. GO:0098692 noradrenergic synapse biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098692 A synapse that uses noradrenaline as a neurotransmitter. GO:0001784 phosphotyrosine residue binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001784 phosphotyrosine binding Interacting selectively and non-covalently with a phosphorylated tyrosine residue within a protein. GO:0098690 glycinergic synapse biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098690 A synapse that uses glycine as a neurotransmitter. GO:0060060 post-embryonic retina morphogenesis in camera-type eye biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060060 The process in which the anatomical structure of the retina is generated and organized in a camera-type eye during the post-embryonic life stage. GO:0060061 Spemann organizer formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060061 Spemann-Mangold organizer formation|Spemann's organizer formation Formation of the specialized region on the dorsalmost side of the embryo that acts as the main signaling center establishing the vertebrate body plan. GO:0060062 Spemann organizer formation at the dorsal lip of the blastopore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060062 Spemann-Mangold organizer formation at the dorsal lip of the blastopore|Spemann's organizer formation at the dorsal lip of the blastopore Formation of the specialized region at the dorsal lip of the blatopore of the embryo that acts as the main signaling center establishing the vertebrate body plan. GO:0001780 neutrophil homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001780 The process of regulating the proliferation and elimination of neutrophils such that the total number of neutrophils within a whole or part of an organism is stable over time in the absence of an outside stimulus. GO:0060063 Spemann organizer formation at the embryonic shield biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060063 Spemann-Mangold organizer formation at the embryonic shield|Spemann's organizer formation at the embryonic shield Formation of the specialized region of the embryonic shield of the embryo that acts as the main signaling center establishing the teleost body plan. GO:0060064 Spemann organizer formation at the anterior end of the primitive streak biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060064 Spemann-Mangold organizer formation at the anterior end of the primitive streak|Spemann organizer formation in amniotes|Spemann's organizer formation at the anterior end of the primitive streak Formation of the specialized region at the anterior end of the primitive streak of the embryo that acts as the main signaling center establishing the body plan. GO:0060065 uterus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060065 Mullerian tract development The reproductive developmental process whose specific outcome is the progression of the uterus over time, from its formation to the mature structure. GO:0060066 oviduct development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060066 fallopian tube development|Mullerian tract development The reproductive developmental process whose specific outcome is the progression of an oviduct over time, from its formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. GO:0060067 cervix development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060067 Mullerian tract development The reproductive developmental process whose specific outcome is the progression of the cervix over time, from its formation to the mature structure. GO:0060068 vagina development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060068 The reproductive developmental process whose specific outcome is the progression of the vagina over time, from its formation to the mature structure. GO:0060069 Wnt signaling pathway, regulating spindle positioning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060069 Wnt receptor signalling pathway, regulating spindle positioning|Wnt receptor signaling pathway, regulating spindle positioning|non-canonical Wnt signaling pathway|Wnt-activated signaling pathway, regulating spindle positioning The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with the positioning of the mitotic spindle. CHEBI:144748 beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_144748 GO:0001789 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001789 GO:0098699 structural constituent of presynaptic actin cytoskeleton biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098699 The action of a molecule that contributes to the structural integrity of a presynaptic actin cytoskeleton. GO:0098664 G protein-coupled serotonin receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098664 G-protein coupled serotonin receptor signaling pathway The series of molecular signals generated as a consequence of a G protein-coupled serotonin receptor binding to one of its physiological ligands. GO:0001752 compound eye photoreceptor fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001752 The process in which the developmental fate of a cell becomes restricted such that it will develop into a compound eye photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments. GO:0001753 obsolete adult eye photoreceptor development (sensu Drosophila) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001753 adult eye photoreceptor development (sensu Drosophila) OBSOLETE. Development of a photoreceptor, a receptor that responds to light, in the adult Drosophila eye. GO:0098665 serotonin receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098665 5HT receptor complex|5-HT receptor complex|5-hydroxytryptamine receptor complex A protein complex that is capable of serotonin receptor activity. GO:0098662 inorganic cation transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098662 inorganic cation membrane transport|monovalent inorganic cation transport|divalent inorganic cation transport|transmembrane inorganic cation transport A process in which an inorganic cation is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. GO:0001754 eye photoreceptor cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001754 The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms. GO:0098663 obsolete transmembrane transporter activity involved in import into cell biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098663 OBSOLETE. Any transmembrane transporter activity that is involved in importing some substance into a cell. GO:0001755 neural crest cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001755 The characteristic movement of cells from the dorsal ridge of the neural tube to a variety of locations in a vertebrate embryo. GO:0098660 inorganic ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098660 inorganic ion membrane transport|transmembrane inorganic ion transport The process in which an inorganic ion is transported across a membrane. GO:0098661 inorganic anion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098661 transmembrane inorganic anion transport|inorganic anion membrane transport The process in which an inorganic anion is transported across a membrane. GO:0060090 molecular adaptor activity biolink:MolecularActivity go-plus goslim_pir|goslim_drosophila http://purl.obolibrary.org/obo/GO_0060090 protein complex scaffold activity|binding, bridging|protein-containing complex scaffold activity The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way. GO:0001750 photoreceptor outer segment biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001750 The outer segment of a vertebrate photoreceptor that contains a stack of membrane discs embedded with photoreceptor proteins. GO:0060091 kinocilium biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0060091 Wikipedia:Kinocilium A nonmotile primary cilium that is found at the apical surface of auditory receptor cells. The kinocilium is surrounded by actin-based stereocilia. GO:0001751 compound eye photoreceptor cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001751 The process in which a relatively unspecialized cell acquires the specialized features of an eye photoreceptor cell. GO:0060092 regulation of synaptic transmission, glycinergic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060092 Any process that modulates the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine. GO:0060093 negative regulation of synaptic transmission, glycinergic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060093 negative regulation of glycinergic synaptic transmission Any process that stops or decreases the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine. GO:0060094 positive regulation of synaptic transmission, glycinergic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060094 positive regulation of glycinergic synaptic transmission Any process that activates or increases the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine. GO:0060095 zinc potentiation of synaptic transmission, glycinergic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060095 zinc potentiation of glycinergic synaptic transmission Any process that activates or increases the frequency, rate or extent of glycinergic synaptic transmission in the presence of zinc. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine. GO:0060096 serotonin secretion, neurotransmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060096 serotonin release, neurotransmission The regulated release of serotonin by a cell, in which released serotonin acts as a neurotransmitter. CHEBI:23098 chiro-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23098 GO:0060097 cytoskeletal rearrangement involved in phagocytosis, engulfment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060097 The assembly, arrangement, or disassembly of cytoskeletal structures that is involved in the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis. GO:0060098 membrane reorganization involved in phagocytosis, engulfment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060098 membrane reorganisation involved in phagocytosis, engulfment The assembly and arrangement of the plasma membrane that is involved in the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis. GO:0060099 regulation of phagocytosis, engulfment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060099 Any process that modulates the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis. GO:0098668 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0098668 GO:0001756 somitogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001756 Wikipedia:Somitogenesis formation of mesodermal clusters The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo. GO:0098669 superinfection exclusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098669 VZ:3971 The process by which a preexisting viral infection prevents a secondary infection with the same or a closely related virus. Typically some aspect of viral entry is inhibited, but post entry mechanisms have also been documented. GO:0001757 somite specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001757 The process in which individual somites establish identity during embryogenesis. GO:0001758 retinal dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001758 RHEA:16177|MetaCyc:RETINAL-DEHYDROGENASE-RXN|Reactome:R-HSA-5362522|EC:1.2.1.36|Reactome:R-HSA-5696101 retinal:NAD+ oxidoreductase activity|cytosolic retinal dehydrogenase activity Catalysis of the reaction: retinal + NAD+ + H2O = retinoate + NADH. Acts on both 11-trans and 13-cis forms of retinal. GO:0098666 G protein-coupled serotonin receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098666 G-protein coupled serotonin receptor complex A protein complex that is capable of G protein-coupled serotonin receptor activity. GO:0001759 organ induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001759 induction of an organ The interaction of two or more cells or tissues that causes them to change their fates and specify the development of an organ. GO:0098667 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0098667 GO:0098675 intrinsic component of neuronal dense core vesicle membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098675 intrinsic to neuronal dense core granule membrane The component of the neuronal dense core vesicle membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0001763 morphogenesis of a branching structure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001763 branching morphogenesis The process in which the anatomical structures of branches are generated and organized. A branch is a division or offshoot from a main stem. Examples in animals would include blood vessels, nerves, lymphatics and other endothelial or epithelial tubes. GO:0098676 modulation of host virulence by virus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098676 VZ:3965 Any process by which a virus modulates the ability of its host to infect and/or damage an organism for which it is a host. Typically this involves a phage modulating the virulence of a bacterium. Mechanisms include the expression of factors that modulate a bacterial adhesion to a host cell, spread through host tissues, production exotoxins or provide protection against host immune defenses. GO:0001764 neuron migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001764 Wikipedia:Neural_development#Neuron_migration|Wikipedia:Neuron_migration neuronal migration|neuron guidance|neuron chemotaxis The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature. GO:0001765 membrane raft assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001765 lipid raft assembly|membrane raft formation|lipid raft formation The aggregation, arrangement and bonding together of a set of components to form a membrane raft, a small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalizes cellular processes. GO:0098673 inhibition of host DNA replication by virus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098673 Any process by which a virus inhibits DNA replication in its host cell. Some bacteriophages are known to do this, possibly as a way of increasing the pool of nucleotides available for virus replication. GO:0001766 membrane raft polarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001766 lipid raft polarization The clustering and aggregation of membrane rafts at a single cellular pole during activation of particular cell types, such as lymphocytes. GO:0098674 extrinsic component of neuronal dense core vesicle membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098674 The component of the neuronal dense core vesicle membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:0098671 adhesion receptor-mediated virion attachment to host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098671 VZ:3943 viral attachment to host adhesion receptor The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface that does not mediate or trigger entry into the host cell. This binding is typically reversible and enhances significantly infectivity by concentrating the virus in the vicinity of its entry receptors, or bringing it to an organ in which its target cells are located. GO:0001760 aminocarboxymuconate-semialdehyde decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001760 EC:4.1.1.45|KEGG_REACTION:R04323|RHEA:16557|MetaCyc:AMINO-CARBOXYMUCONATE-SEMIALDEHYDE-RXN picolinic acid decarboxylase activity|picolinic acid carboxylase activity|2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate carboxy-lyase (2-aminomuconate-semialdehyde-forming)|2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate carboxy-lyase activity|2-amino-3-(3-oxoprop-2-enyl)but-2-enedioate carboxy-lyase activity|alpha-amino-beta-carboxymuconate-epsilon-semialdehyde beta-decarboxylase activity|ACMSD activity|alpha-amino-beta-carboxymuconate-epsilon-semialdehade decarboxylase activity Catalysis of the reaction: 2-amino-3-carboxymuconate 6-semialdehyde + H(+) = 2-aminomuconate 6-semialdehyde + CO(2). GO:0098672 evasion by virus of CRISPR-cas system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098672 VZ:3962 CRISPR-cas system evasion by virus Any process, either active or passive, by which a virus evades the CRISPR-cas system of its host. Some viruses can directly suppress the CRISPR system. GO:0001761 beta-alanine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001761 beta-alanine transporter activity Enables the transfer of beta-alanine from one side of a membrane to the other. Beta-alanine is 3-aminopropanoic acid. GO:0001762 beta-alanine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001762 The directed movement of beta-alanine, 3-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0060080 inhibitory postsynaptic potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060080 regulation of inhibitory post-synaptic membrane potential|IPSP A process that causes a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential. GO:0098670 entry receptor-mediated virion attachment to host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098670 VZ:3942 viral attachment to host entry receptor The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface that mediates/triggers viral entry by endocytosis/pinocytosis or by inducing fusion/penetration. GO:0060081 membrane hyperpolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060081 The process in which membrane potential increases with respect to its steady-state potential, usually from negative potential to a more negative potential. For example, during the repolarization phase of an action potential the membrane potential often becomes more negative or hyperpolarized before returning to the steady-state resting potential. GO:0060082 eye blink reflex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060082 nictitating membrane reflex The reflex process in which a mechanical stimulus applied to the eye elicits a response of the eyelid closing. GO:0060083 smooth muscle contraction involved in micturition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060083 smooth muscle contraction involved in urination|urinary bladder smooth muscle contraction involved in micturition The process leading to shortening and/or development of tension in the urinary bladder smooth muscle tissue involved in the expulsion urine from the body. GO:0060084 synaptic transmission involved in micturition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060084 synaptic transmission involved in urination The process of communication from a neuron to a smooth muscle in the bladder that contributes to the expulsion of urine from the body. GO:0060085 smooth muscle relaxation of the bladder outlet biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060085 synaptic transmission involved in urination A process in which the extent of smooth muscle contraction is reduced in the bladder outlet that contributes to the expulsion of urine from the body. GO:0060086 circadian temperature homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060086 circadian thermoregulation|circadian regulation of body temperature Any homeostatic process in which an organism modulates its internal body temperature at different values with a regularity of approximately 24 hours. GO:0060087 relaxation of vascular associated smooth muscle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060087 vascular smooth muscle relaxation|relaxation of vascular smooth muscle|negative regulation of relaxation of vascular smooth muscle|positive regulation of relaxation of vascular smooth muscle|regulation of relaxation of vascular smooth muscle A negative regulation of smooth muscle contraction resulting in relaxation of vascular smooth muscle. The relaxation is mediated by a decrease in the phosphorylation state of myosin light chain. This can be achieved by removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases leading to a decrease myosin light chain kinase activity, and through calcium-independent pathways leading to a increase in myosin light chain phosphatase activity. GO:0060088 auditory receptor cell stereocilium organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060088 auditory receptor cell stereocilium organization and biogenesis|auditory receptor cell stereocilium organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of auditory hair cells. GO:0060089 molecular transducer activity biolink:MolecularActivity go-plus gocheck_do_not_manually_annotate|goslim_pir http://purl.obolibrary.org/obo/GO_0060089 A compound molecular function in which an effector function is controlled by one or more regulatory components. GO:0001767 establishment of lymphocyte polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001767 lymphocyte polarization The directed orientation of lymphocyte signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with an appropriate activating cell. GO:0098679 obsolete regulation of carbohydrate catabolic process by regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098679 regulation of carbohydrate catabolism by regulation of transcription from RNA polymerase II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of carbohydrate catabloism. GO:0001768 establishment of T cell polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001768 establishment of T-cell polarity|T-cell polarization|establishment of T lymphocyte polarity|T lymphocyte polarization|establishment of T-lymphocyte polarity|T cell polarization The directed orientation of T cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with antigen presenting cell. CHEBI:144729 L-beta-ethynylserine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_144729 GO:0098677 virion maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098677 UniProtKB-KW:KW-0917|VZ:1946 viral particle maturation|virus particle maturation Maturation of a virion after separation from the host cell. Not all viruses mature after separation. In those that do, maturation typically involves rearangement and/or cleavage of viral proteins, resulting in the virion becoming competent for reinfection. GO:0001769 establishment of B cell polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001769 establishment of B lymphocyte polarity|B lymphocyte polarization|establishment of B-lymphocyte polarity|B cell polarization|establishment of B-cell polarity|B-cell polarization The directed orientation of B cell signaling molecules and associated membrane rafts towards a chemokine gradient of a contact point with an antigen displaying cell. GO:0098678 viral tropism switching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098678 VZ:4498 A process by which the range of hosts which a virus can bind and infect is changed. Examples include phages that switch between types of fibers via the action of a virally encoded invertase. GO:0001730 2'-5'-oligoadenylate synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001730 Reactome:R-HSA-8983680|EC:2.7.7.84|MetaCyc:RXN-13648|MetaCyc:RXN-10798|Reactome:R-HSA-8985091|RHEA:34407|Reactome:R-HSA-8985104 oligo-2',5'-adenylate synthetase activity|2'-5' oligoadenylate synthetase activity|(2-5')oligo(A) synthetase activity|2-5A synthetase activity Catalysis of the reaction: ATP = pppA(2'p5'A)n oligomers. This reaction requires the binding of double-stranded RNA. GO:0001731 formation of translation preinitiation complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001731 translation preinitiation complex assembly|formation of translation pre-initiation complex The joining of the small ribosomal subunit, ternary complex, and mRNA. GO:0001732 formation of cytoplasmic translation initiation complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001732 translation initiation complex assembly|cytoplasmic translation initiation complex assembly|formation of translation initiation complex Joining of the large subunit, with release of IF2/eIF2 and IF3/eIF3. This leaves the functional ribosome at the AUG, with the methionyl/formyl-methionyl-tRNA positioned at the P site. GO:0001733 galactosylceramide sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001733 MetaCyc:GALACTOSYLCERAMIDE-SULFOTRANSFERASE-RXN|RHEA:43304|EC:2.8.2.11 GSase|3'-phosphoadenosine-5'-phosphosulfate-cerebroside sulfotransferase activity|3'-phosphoadenylyl-sulfate:galactosylceramide 3'-sulfotransferase activity|galactolipid sulfotransferase activity|cerebroside sulfotransferase activity|glycosphingolipid sulfotransferase activity|galactocerebroside sulfotransferase activity|galactosylceramide sulphotransferase activity|glycolipid sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a galactosylceramide = adenosine 3',5'-bisphosphate + a galactosylceramidesulfate. CHEBI:23079 cerebroside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23079 UBERON:0000414 mucous gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000414 mucous secreting gland|mucus-secreting gland|glandula mucosa|muciparous gland|mucus gland A gland in which the principal secretory cells are mucus secreting cells. UBERON:0000415 artery wall biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000415 wall of artery|arterial wall An anatomical wall that is part of an artery [Automatically generated definition]. CHEBI:144711 N-stearoyl-sphingoid base biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_144711 CHEBI:144712 N-(very-long-chain fatty acyl)-sphingoid base biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_144712 CHEBI:23073 glycopentaosylceramide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23073 CHEBI:47040 lipid A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47040 CHEBI:47041 tetrahydroxytetrahydrofuran biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47041 CHEBI:47042 hydroxycalciol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47042 CHEBI:23075 glycotetraosylceramide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23075 CHEBI:62600 2-O-(alpha-D-glucopyranosyl)-3-O-phosphonato-D-glycerate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62600 CHEBI:62601 2-O-(alpha-D-glucopyranosyl)-3-O-phospho-D-glyceric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62601 CHEBI:62602 2-O-[alpha-D-mannopyranosyl-(1->2)-alpha-D-glucopyranosyl]-3-O-phosphonato-D-glycerate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62602 CHEBI:62603 2-O-[alpha-D-mannopyranosyl-(1->2)-alpha-D-glucopyranosyl]-3-O-phospho-D-glyceric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62603 GO:0001738 morphogenesis of a polarized epithelium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001738 epithelial polarization The morphogenetic process in which the anatomical structures of a polarized epithelium are generated and organized. A polarized epithelium is an epithelium where the epithelial sheet is oriented with respect to the planar axis. CHEBI:144713 N-(ultra-long-chain-acyl)-sphingoid base biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_144713 CHEBI:62608 EC 4.2.1.3 (aconitate hydratase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62608 GO:0001739 sex chromatin biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001739 Chromatin that is part of a sex chromosome. CHEBI:62609 EC 3.11.1.3 (phosphonopyruvate hydrolase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62609 GO:0001734 mRNA (N6-adenosine)-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001734 Reactome:R-HSA-72095 Catalysis of the reaction: S-adenosyl-L-methionine + RRACH = S-adenosyl-L-homocysteine + RRm6ACH; R is a purine, and H is C, A, or U. GO:0001735 prenylcysteine oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001735 MetaCyc:1.8.3.5-RXN|RHEA:53892|EC:1.8.3.5 prenylcysteine lyase activity|S-prenyl-L-cysteine:oxygen oxidoreductase activity Catalysis of the reaction: S-prenyl-L-cysteine + O2 + H2O = a prenal + L-cysteine + H2O2. GO:0001736 establishment of planar polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001736 establishment of planar cell polarity Coordinated organization of groups of cells in the plane of an epithelium, such that they all orient to similar coordinates. GO:0001737 establishment of imaginal disc-derived wing hair orientation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001737 establishment of wing hair orientation Orientation of hairs in the imaginal disc-derived wing along a proximal-distal axis, such that each cell of the wing produces one wing hair which points in a distal direction. GO:0001741 XY body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001741 A structure found in a male mammalian spermatocyte containing an unpaired X chromosome that has become densely heterochromatic, silenced and localized at the nuclear periphery. UBERON:0000407 sympathetic trunk biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000407 truncus sympathicus|gangliated cord|sympathetic chain|sympathetic ganglionic chain One of a a paired bundle of nerve fibers plus ganglia that run from the base of the skull to the coccyx. GO:0001742 oenocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001742 oenocyte cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of an oenocyte. Oenocytes are large secretory cells found in clusters underlying the epidermis of larval abdominal segments. CHEBI:47037 cyclic purine dinucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47037 GO:0001743 optic placode formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001743 The initial developmental process that will lead to the formation of an eye. CHEBI:23089 chelate-forming peptide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23089 GO:0001744 optic lobe placode formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001744 optic lobe and Bolwig's organ precursor formation Establishment of the optic placode, a thickened area of densely packed ectoderm cells directly overlying the optic vesicle in the early embryo. In Drosophila, for example, the placode appears in the dorsolateral region of the head in late stage 11 embryos and is the precursor to the larval visual system. CHEBI:47039 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47039 UBERON:0000409 serous gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000409 A gland in which the principal secretory cells are serous secreting cells. UBERON:0000402 nasal vestibule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000402 vestibulum nasi|vestibulum nasale|vestibular part of nasal cavity The nasal vestibule is the most anterior part of the nasal cavity. It's enclosed by the cartilages of nose and lined by the same epithelium of the skin. The other part of the nasal cavity, which is lined by the respiratory epithelium, is called nasal cavity proper. [WP,unvetted]. GO:0001740 Barr body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001740 Wikipedia:Barr_body|NIF_Subcellular:sao1571698684 A structure found in a female mammalian cell containing an unpaired X chromosome that has become densely heterochromatic, silenced and localized at the nuclear periphery. CHEBI:23084 cetraxates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23084 CHEBI:47031 LL-2,6-diaminopimelate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47031 CHEBI:203600 1D-myo-inositol 1,4,5-trisphosphate(6-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_203600 CHEBI:23086 chalcones biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23086 CHEBI:62611 (S)-3-hydroxyisobutyryl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62611 CHEBI:62612 (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62612 CHEBI:62615 3-oxolauroyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62615 CHEBI:62616 (S)-3-hydroxydecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62616 CHEBI:62613 (S)-3-hydroxypalmitoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62613 CHEBI:62614 (S)-3-hydroxytetradecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62614 CHEBI:62619 3-oxooctanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62619 GO:0001749 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001749 UBERON:0000410 bronchial mucosa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000410 mucosa of bronchus|tunica mucosa bronchi|bronchial trunk organ mucosa|mucous membrane of bronchus|bronchi organ mucosa|bronchi mucosa of organ|organ mucosa of bronchi|organ mucosa of bronchial trunk|bronchial trunk mucosa of organ|bronchus mucosa of organ|bronchi mucous membrane|bronchial trunk mucous membrane|bronchus mucous membrane|bronchus mucosa|bronchial trunk mucosa|bronchi mucosa|organ mucosa of bronchus|mucous membrane of bronchi|mucosa of bronchi|mucous membrane of bronchial trunk|mucosa of bronchial trunk|mucosa of organ of bronchi|mucosa of organ of bronchial trunk|mucosa of organ of bronchus|bronchus organ mucosa A mucosa that is part of a bronchus [Automatically generated definition]. CHEBI:144703 N-palmitoyl-sphingoid base biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_144703 CHEBI:62617 (S)-3-hydroxyoctanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62617 CHEBI:62618 hydroxyacyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62618 GO:0001745 compound eye morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001745 insect-type retina morphogenesis The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster. GO:0001746 Bolwig's organ morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001746 The morphogenetic process in which the anatomical structures of the larval eye in Drosophila are generated and organized. The larval eye in Drosophila is a relatively simple sensory system composed of Bolwig's organs: two clusters, each composed of 12 photoreceptor cells from which axons extend in a single fascicle to the brain. GO:0001747 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001747 GO:0001748 optic lobe placode development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001748 optic lobe and Bolwig's organ precursor development|optic placode development The process whose specific outcome is the progression of the optic placode over time, from its formation to the mature structure. During embryonic stage 12 the placode starts to invaginate, forming a pouch. Cells that will form Bolwig's organ segregate from the ventral lip of this pouch, remaining in the head epidermis. The remainder of the invagination loses contact with the outer surface and becomes the optic lobe. An example of this process is found in Drosophila melanogaster. CHEBI:47025 UDP-4-amino-4-deoxy-beta-L-arabinopyranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47025 CHEBI:47027 UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47027 GO:0001710 mesodermal cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001710 mesoderm cell fate commitment The cell differentiation process that results in commitment of a cell to become part of the mesoderm. CHEBI:47028 UDP-beta-L-threo-pentopyranos-4-ulose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47028 GO:0001711 endodermal cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001711 endoderm cell fate commitment The cell differentiation process that results in commitment of a cell to become part of the endoderm. CHEBI:47024 aldehydo-ribose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47024 CHEBI:23053 catechin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_23053 CHEBI:37699 protein kinase inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37699 CHEBI:62622 (5-hydroxyindol-3-yl)acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62622 CHEBI:62620 hexanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62620 CHEBI:37697 indolocarbazole alkaloid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37697 CHEBI:62621 L-selenomethionine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62621 CHEBI:62626 uroporphyrinogen I(8-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62626 CHEBI:62624 5-hydroxy-L-kynurenine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62624 GO:0001716 L-amino-acid oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001716 Reactome:R-HSA-2160492|RHEA:13781|EC:1.4.3.2|MetaCyc:L-AMINO-ACID-OXIDASE-RXN L-amino-acid:oxygen oxidoreductase (deaminating)|ophio-amino-acid oxidase activity Catalysis of the reaction: a L-amino acid + H2O + O2 = a 2-oxo acid + NH3 + hydrogen peroxide. GO:0001717 conversion of seryl-tRNAsec to selenocys-tRNAsec biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001717 The modification process that results in the conversion of serine, carried by a specialized tRNA(ser) (which can read a UGA anticodon), to selenocysteine. GO:0001718 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001718 GO:0001719 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001719 CHEBI:37690 allose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37690 GO:0001712 ectodermal cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001712 ectoderm cell fate commitment The cell differentiation process that results in commitment of a cell to become part of the ectoderm. GO:0001713 ectodermal cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001713 ectoderm cell fate determination The cell fate determination process that results in a cell becoming capable of differentiating autonomously into an ectoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed. CHEBI:37696 carbohydrate acid ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37696 GO:0001714 endodermal cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001714 endoderm cell fate specification The cell fate determination process that results in a cell becoming capable of differentiating autonomously into an endoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. GO:0001715 ectodermal cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001715 ectoderm cell fate specification The cell fate determination process that results in a cell becoming becomes capable of differentiating autonomously into an ectoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. CHEBI:37694 O-phospho peptide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37694 CHEBI:47014 aldehydo-D-ribose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47014 CHEBI:47015 aldehydo-L-ribose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47015 GO:0001720 conversion of lysyl-tRNA to pyrrolysyl-tRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001720 The modification process that results in the conversion of lysine, carried by a specialized lysine-accepting tRNA (possessing a CUA anticodon), to pyrrolysine (a lysine with an amide linkage to a (4R,5R)-4-substituted pyrroline-5-carboxylate). GO:0001721 obsolete intermediate filament associated protein biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001721 intermediate filament associated protein|IFAP OBSOLETE. Proteins that associate with intermediate filaments and function in the supramolecular organization of cellular intermediate filament networks. CHEBI:47016 tetrahydrofuranone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47016 GO:0001722 obsolete type I intermediate filament associated protein biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001722 type I intermediate filament associated protein OBSOLETE. Low molecular weight (10-45 kDa) proteins that associate with intermediate filaments by lateral binding of the filaments and have the effect of creating tight macrofilament aggregates. CHEBI:47017 tetrahydrofuranol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47017 CHEBI:47018 monohydroxytetrahydrofuran biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47018 CHEBI:47019 dihydroxytetrahydrofuran biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47019 CHEBI:47010 L-ribopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47010 CHEBI:23066 cephalosporin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23066 CHEBI:47012 beta-L-ribopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47012 CHEBI:47013 D-ribofuranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47013 CHEBI:23064 cephalosporanic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23064 CHEBI:62631 coproporphyrinogen I(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62631 CHEBI:62637 L-4-hydroxyglutamate semialdehyde zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62637 CHEBI:62638 (S)-3-hydroxyisobutyrate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62638 GO:0001727 lipid kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001727 Catalysis of the phosphorylation of a simple or complex lipid. GO:0001728 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001728 GO:0001729 ceramide kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001729 RHEA:17929|Reactome:R-HSA-1638845|MetaCyc:CERAMIDE-KINASE-RXN|EC:2.7.1.138 ATP:ceramide 1-phosphotransferase activity|acylsphingosine kinase activity Catalysis of the reaction: ATP + ceramide = ADP + ceramide-1-phosphate. CHEBI:62639 2-cis,6-trans,10-trans-geranylgeranyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62639 GO:0001723 obsolete type II intermediate filament associated protein biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001723 type II intermediate filament associated protein OBSOLETE. High molecular weight (100-300 kDa) proteins that associate with intermediate filaments to cross-link them into loose networks. GO:0001724 obsolete type III intermediate filament associated protein biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001724 type III intermediate filament associated protein OBSOLETE. Proteins that associate with the ends of intermediate filaments and couple the intermediate filaments to the plasma membrane. GO:0001725 stress fiber biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001725 actin cable|stress fibre A contractile actin filament bundle that consists of short actin filaments with alternating polarity, cross-linked by alpha-actinin and possibly other actin bundling proteins, and with myosin present in a periodic distribution along the fiber. GO:0001726 ruffle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001726 membrane ruffle Projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork. GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050664 EC:1.6.3.- oxidoreductase activity, acting on NADH or NADPH, oxygen as acceptor Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces an oxygen molecule. GO:0050665 hydrogen peroxide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050665 hydrogen peroxide anabolism|H2O2 biosynthetic process|hydrogen peroxide synthesis|hydrogen peroxide formation|hydrogen peroxide generation|hydrogen peroxide biosynthesis The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA. GO:0050662 obsolete coenzyme binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050662 OBSOLETE. Interacting selectively and non-covalently with a coenzyme, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed. GO:0050663 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050663 GO:1902418 (+)-abscisic acid D-glucopyranosyl ester transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902418 abscisic acid glucosyl ester transmembrane transport|ABA-GE transmembrane transport The process in which (+)-abscisic acid D-glucopyranosyl este is transported across a membrane. GO:0050668 positive regulation of homocysteine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050668 up regulation of homocysteine metabolic process|positive regulation of homocysteine metabolism|upregulation of homocysteine metabolic process|positive regulation of Hcy metabolic process|stimulation of homocysteine metabolic process|positive regulation of Hcy metabolism|activation of homocysteine metabolic process|up-regulation of homocysteine metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving homocysteine. GO:1902419 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902419 GO:0050669 negative regulation of homocysteine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050669 down-regulation of homocysteine metabolic process|downregulation of homocysteine metabolic process|negative regulation of homocysteine metabolism|down regulation of homocysteine metabolic process|inhibition of homocysteine metabolic process|negative regulation of Hcy metabolism|negative regulation of Hcy metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving homocysteine. GO:1902416 positive regulation of mRNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902416 up regulation of mRNA binding|upregulation of mRNA binding|up-regulation of mRNA binding|activation of mRNA binding Any process that activates or increases the frequency, rate or extent of mRNA binding. GO:0050666 regulation of homocysteine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050666 regulation of Hcy metabolism|regulation of homocysteine metabolism|regulation of Hcy metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid. GO:1902417 (+)-abscisic acid D-glucopyranosyl ester transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1902417 ABA-GE transmembrane transporter activity|abscisic acid glucosyl ester transmembrane transporter activity Enables the transfer of (+)-abscisic acid D-glucopyranosyl ester from one side of a membrane to the other. GO:0050667 homocysteine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050667 homocysteine metabolism|Hcy metabolism|Hcy metabolic process The chemical reactions and pathways involving homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid. Homocysteine is an important intermediate in the metabolic reactions of its S-methyl derivative, methionine. GO:1902414 protein localization to cell junction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902414 protein localisation to cell junction|protein localization in cell junction|protein localisation in cell junction A process in which a protein is transported to, or maintained in, a location within a cell junction. GO:1902415 regulation of mRNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902415 Any process that modulates the frequency, rate or extent of mRNA binding. GO:1902412 regulation of mitotic cytokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902412 regulation of cytokinesis after mitosis Any process that modulates the frequency, rate or extent of mitotic cytokinesis. GO:1902413 negative regulation of mitotic cytokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902413 inhibition of cytokinesis after mitosis|down-regulation of mitotic cytokinesis|inhibition of mitotic cytokinesis|down regulation of cytokinesis after mitosis|downregulation of cytokinesis after mitosis|down regulation of mitotic cytokinesis|down-regulation of cytokinesis after mitosis|negative regulation of cytokinesis after mitosis|downregulation of mitotic cytokinesis Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cytokinesis. GO:1902410 mitotic cytokinetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902410 Any cytokinetic process that is involved in mitotic cell cycle. GO:1902411 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902411 GO:0035023 regulation of Rho protein signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035023 Any process that modulates the frequency, rate or extent of Rho protein signal transduction. GO:0035024 negative regulation of Rho protein signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035024 down regulation of Rho protein signal transduction|downregulation of Rho protein signal transduction|down-regulation of Rho protein signal transduction|inhibition of Rho protein signal transduction Any process that stops, prevents, or reduces the frequency, rate or extent of Rho protein signal transduction. GO:0035025 positive regulation of Rho protein signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035025 upregulation of Rho protein signal transduction|up regulation of Rho protein signal transduction|activation of Rho protein signal transduction|stimulation of Rho protein signal transduction|up-regulation of Rho protein signal transduction Any process that activates or increases the frequency, rate or extent of Rho protein signal transduction. GO:0035026 leading edge cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035026 The process in which relatively unspecialized cells acquire specialized structural and/or functional features of leading edge cells, cells at the front of a migrating epithelial sheet. GO:0035027 leading edge cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035027 The commitment of cells to leading edge cell fate and their capacity to differentiate into leading edge cells. Leading edge cells are found at the front of a migrating epithelial sheet. GO:0035028 leading edge cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035028 The process in which a cell becomes capable of differentiating autonomously into a leading edge cell regardless of its environment; upon determination, the cell fate cannot be reversed. GO:0098608 methylselenol demethylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098608 Reactome:R-HSA-2408530 Catalysis of the reaction: methylselenol + H2O => H2Se + CH3OH. GO:0035029 dorsal closure, leading edge cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035029 The commitment of cells to leading edge cell fate during dorsal closure. Leading edge cells are the dorsal-most cells of the migrating epidermis. GO:0098609 cell-cell adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098609 single organismal cell-cell adhesion The attachment of one cell to another cell via adhesion molecules. GO:0098606 selenocystathionine gamma-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098606 Reactome:R-HSA-2408543|RHEA:31151 Catalysis of the reaction: L-Selenocystathionine + H2O => L-Selenocysteine + NH3 + 2-Oxobutanoic acid. GO:0098607 methylselenocysteine deselenhydrase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098607 Reactome:R-HSA-2408539 Catalysis of the reaction: Se-Methyl-L-selenocysteine + H2O => pyruvic acid + NH3 + Methaneselenol. GO:0098604 adenosylselenohomocysteinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098604 Reactome:R-HSA-2408532 Catalysis of the reaction: Se-Adenosyl-L-selenohomocysteine + H2O => Adenosine + Selenohomocysteine. GO:0098605 selenocystathionine beta-synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098605 Reactome:R-HSA-2408559 Catalysis of the reaction: L-Serine + Selenohomocysteine => L-Selenocystathionine + H2O. GO:0050660 flavin adenine dinucleotide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050660 FAD or FADH2 binding|flavine-adenine dinucleotide binding Interacting selectively and non-covalently with FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2. GO:0098602 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0098602 GO:0050661 NADP binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050661 nicotinamide adenine dinucleotide phosphate binding|NADP or NADPH binding|NADP+ or NADPH binding Interacting selectively and non-covalently with nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH. GO:0098603 selenol Se-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098603 Reactome:R-HSA-2408544 Catalysis of the reaction: R + Se-Adenosylselenomethionine => CH3-R + Se-Adenosyl-L-selenohomocysteine. GO:0035020 regulation of Rac protein signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035020 Any process that modulates the frequency, rate or extent of Rac protein signal transduction. GO:0098600 selenomethionine gamma-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098600 Reactome:R-HSA-2408537 Catalysis of the reaction: L-Selenomethionine + H2O => Methaneselenol + Ammonia + 2-oxobutanoic acid. GO:0035021 negative regulation of Rac protein signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035021 down regulation of Rac protein signal transduction|downregulation of Rac protein signal transduction|down-regulation of Rac protein signal transduction|inhibition of Rac protein signal transduction Any process that stops, prevents, or reduces the frequency, rate or extent of Rac protein signal transduction. GO:0035022 positive regulation of Rac protein signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035022 upregulation of Rac protein signal transduction|up regulation of Rac protein signal transduction|activation of Rac protein signal transduction|stimulation of Rac protein signal transduction|up-regulation of Rac protein signal transduction Any process that activates or increases the frequency, rate or extent of Rac protein signal transduction. GO:0098601 selenomethionine adenosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098601 Reactome:R-HSA-2408551|RHEA:31211 Catalysis of the reaction: ATP + L-Selenomethionine + H2O => Orthophosphate + Diphosphate + Se-Adenosylselenomethionine. GO:0050675 regulation of urothelial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050675 Any process that modulates the frequency, rate or extent of urothelial cell proliferation. GO:0098610 adhesion between unicellular organisms biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098610 multi-organismal cell-cell adhesion|adhesion between unicellular organisms via cell-wall interaction The attachment of two unicellular organisms to each other. GO:0050676 negative regulation of urothelial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050676 down-regulation of urothelial cell proliferation|inhibition of urothelial cell proliferation|down regulation of urothelial cell proliferation|downregulation of urothelial cell proliferation Any process that stops, prevents or reduces the rate or extent of urothelial cell proliferation. GO:0050673 epithelial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050673 The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances. GO:0050674 urothelial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050674 The multiplication or reproduction of urothelial cells, resulting in the expansion of a cell population. Urothelial cells make up a layer of transitional epithelium in the wall of the bladder, ureter, and renal pelvis, external to the lamina propria. GO:0050679 positive regulation of epithelial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050679 up-regulation of epithelial cell proliferation|upregulation of epithelial cell proliferation|up regulation of epithelial cell proliferation|activation of epithelial cell proliferation|stimulation of epithelial cell proliferation Any process that activates or increases the rate or extent of epithelial cell proliferation. GO:1902429 positive regulation of water channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902429 upregulation of water channel activity|activation of aquaporin|up-regulation of aquaporin|up-regulation of water channel activity|activation of water channel activity|aquaporin activation|upregulation of aquaporin|up regulation of water channel activity|up regulation of aquaporin|positive regulation of aquaporin Any process that activates or increases the frequency, rate or extent of water channel activity. GO:0050677 positive regulation of urothelial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050677 up regulation of urothelial cell proliferation|activation of urothelial cell proliferation|stimulation of urothelial cell proliferation|up-regulation of urothelial cell proliferation|upregulation of urothelial cell proliferation Any process that activates or increases the rate or extent of urothelial cell proliferation. GO:1902427 regulation of water channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902427 regulation of aquaporin|regulation of aquaporin permeability Any process that modulates the frequency, rate or extent of water channel activity. GO:1902428 negative regulation of water channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902428 down regulation of water channel activity|inhibition of water channel activity|negative regulation of aquaporin|down-regulation of aquaporin|inhibition of aquaporin|down-regulation of water channel activity|down regulation of aquaporin|downregulation of aquaporin|downregulation of water channel activity Any process that stops, prevents or reduces the frequency, rate or extent of water channel activity. GO:0050678 regulation of epithelial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050678 Any process that modulates the frequency, rate or extent of epithelial cell proliferation. GO:1902425 positive regulation of attachment of mitotic spindle microtubules to kinetochore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902425 up regulation of attachment of spindle microtubules to kinetochore involved in mitosis|up regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|activation of attachment of spindle microtubules to kinetochore involved in mitosis|upregulation of mitotic bipolar attachment|positive regulation of attachment of spindle microtubules to kinetochore involved in mitosis|up-regulation of attachment of spindle microtubules to mitotic chromosome|activation of attachment of spindle microtubules to mitotic chromosome|upregulation of attachment of spindle microtubules to kinetochore during mitosis|upregulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|up-regulation of mitotic bipolar attachment|up-regulation of attachment of spindle microtubules to kinetochore involved in mitosis|positive regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|positive regulation of attachment of spindle microtubules to mitotic chromosome|up-regulation of attachment of spindle microtubules to kinetochore during mitosis|up regulation of attachment of spindle microtubules to mitotic chromosome|activation of mitotic bipolar attachment|activation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|up-regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|activation of attachment of spindle microtubules to kinetochore during mitosis|positive regulation of mitotic bipolar attachment|upregulation of attachment of spindle microtubules to kinetochore involved in mitosis|up regulation of mitotic bipolar attachment|positive regulation of attachment of spindle microtubules to kinetochore during mitosis|upregulation of attachment of spindle microtubules to mitotic chromosome|up regulation of attachment of spindle microtubules to kinetochore during mitosis Any process that activates or increases the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation. GO:1902426 deactivation of mitotic spindle assembly checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902426 inhibition of Mad2-dependent checkpoint|inhibition of mitotic spindle assembly checkpoint|mitotic spindle assembly checkpoint silencing|negative regulation of mitotic cell cycle spindle assembly checkpoint|down-regulation of mitotic cell cycle spindle assembly checkpoint|down regulation of Mad2-dependent checkpoint|negative regulation of mitotic spindle assembly checkpoint|downregulation of Mad2-dependent checkpoint|down regulation of mitotic spindle assembly checkpoint|downregulation of mitotic cell cycle spindle assembly checkpoint|down regulation of mitotic cell cycle spindle assembly checkpoint|downregulation of mitotic spindle assembly checkpoint|inhibition of mitotic cell cycle spindle assembly checkpoint|mitotic spindle assembly deactivation|negative regulation of Mad2-dependent checkpoint|down-regulation of Mad2-dependent checkpoint|down-regulation of mitotic spindle assembly checkpoint A positive regulation of the mitotic metaphase/anaphase transition that results from deactivation of the mitotic spindle assembly checkpoint. GO:1902423 regulation of attachment of mitotic spindle microtubules to kinetochore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902423 regulation of mitotic bipolar attachment|regulation of attachment of spindle microtubules to kinetochore during mitosis|regulation of attachment of spindle microtubules to mitotic chromosome|regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|regulation of mitotic attachment of spindle microtubules to kinetochore|regulation of attachment of spindle microtubules to kinetochore involved in mitosis Any process that modulates the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation. GO:1902424 negative regulation of attachment of mitotic spindle microtubules to kinetochore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902424 downregulation of attachment of spindle microtubules to kinetochore involved in mitosis|downregulation of attachment of spindle microtubules to kinetochore during mitosis|down regulation of mitotic bipolar attachment|down regulation of attachment of spindle microtubules to kinetochore during mitosis|downregulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|negative regulation of mitotic attachment of spindle microtubules to kinetochore|negative regulation of attachment of spindle microtubules to kinetochore involved in mitosis|down-regulation of attachment of spindle microtubules to kinetochore involved in mitosis|inhibition of mitotic bipolar attachment|down regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|inhibition of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|inhibition of attachment of spindle microtubules to kinetochore during mitosis|down-regulation of attachment of spindle microtubules to mitotic chromosome|negative regulation of attachment of spindle microtubules to mitotic chromosome|negative regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|inhibition of attachment of spindle microtubules to kinetochore involved in mitosis|downregulation of attachment of spindle microtubules to mitotic chromosome|negative regulation of mitotic bipolar attachment|down-regulation of mitotic bipolar attachment|negative regulation of attachment of spindle microtubules to kinetochore during mitosis|down-regulation of attachment of spindle microtubules to kinetochore during mitosis|down regulation of attachment of spindle microtubules to mitotic chromosome|down regulation of attachment of spindle microtubules to kinetochore involved in mitosis|inhibition of attachment of spindle microtubules to mitotic chromosome|down-regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|downregulation of mitotic bipolar attachment Any process that stops, prevents or reduces the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation. GO:1902421 hydrogen metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902421 H2 metabolism|molecular hydrogen metabolism|dihydrogen metabolism The chemical reactions and pathways involving H2 (dihydrogen). GO:1902422 hydrogen biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902422 dihydrogen synthesis|hydrogen anabolism|hydrogen generation|hydrogen synthesis|hydrogen formation|H2 biosynthesis|hydrogen biosynthesis|molecular hydrogen biosynthesis|hydrogen production The chemical reactions and pathways resulting in the formation of H2 (dihydrogen). GO:1902420 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902420 GO:0035012 obsolete polytene chromosome, telomeric region biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035012 OBSOLETE. The terminal region of a polytene chromosome. GO:0035013 myosuppressin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035013 Combining with the peptide myosuppressin to initiate a change in cell activity. GO:0035014 phosphatidylinositol 3-kinase regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035014 phosphoinositide 3-kinase regulator activity|PI3K regulator activity Modulates the activity of any of the phosphatidylinositol 3-kinases (PI3Ks). Regulatory subunits can link a PI3K catalytic subunit to upstream signaling events and help position the catalytic subunits close to their lipid substrates. GO:0035015 elongation of arista core biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035015 The increase in length of the aristal core. The arista is the terminal segment of the antenna and consists of a central core and a series of lateral extensions. GO:0035016 elongation of arista lateral biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035016 The increase in length of the aristal laterals. The arista is the terminal segment of the antenna and consists of a central core and a series of lateral extensions. GO:0035017 cuticle pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035017 The regionalization process that gives rise to the patterns of cell differentiation in the cuticle. GO:0098619 selenocysteine-tRNA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098619 Reactome:R-HSA-2408526 Catalysis of the reaction: tRNASec + L-Ser + ATP = Ser-tRNASec + AMP + diphosphate. GO:0035018 adult chitin-based cuticle pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035018 adult cuticle pattern formation The process that gives rise to the patterns of cell differentiation that will arise in the chitin-based adult cuticle. An example of this process is adult chitin-based cuticle pattern formation in Drosophila melanogaster. GO:0035019 somatic stem cell population maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035019 Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line. GO:0098617 adenylylselenate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098617 Reactome:R-HSA-2408540 Catalysis of the reaction: ATP + adenylylselenate => ADP + 3'-phosphoadenylylselenate. GO:0098618 selenomethionine-tRNA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098618 Reactome:R-HSA-2408546 Catalysis of the reaction: ATP + L-selenomethionine + tRNA(Met) => AMP + diphosphate + selenomethionyl-tRNA(Met). GO:0098615 dimethyl selenide methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098615 Reactome:R-HSA-2408554 Catalysis of the reaction: S-adenosyl-L-methionine + dimethyl selenide => S-adenosyl-L-homocysteine + trimethylselenonium. GO:0098616 selenate adenylyltransferase (ATP) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098616 Reactome:R-HSA-2408525 Catalysis of the reaction: ATP + H2SeO4 => diphosphate + adenylylselenate. GO:0098613 methaneselenol methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098613 Reactome:R-HSA-2408541 Catalysis of the reaction: S-adenosyl-L-methionine + methaneselenol => S-adenosyl-L-homocysteine + dimethyl selenide. GO:0050671 positive regulation of lymphocyte proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050671 up regulation of lymphocyte proliferation|upregulation of lymphocyte proliferation|stimulation of lymphocyte proliferation|up-regulation of lymphocyte proliferation|activation of lymphocyte proliferation Any process that activates or increases the rate or extent of lymphocyte proliferation. GO:0098614 hydrogen selenide methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098614 Reactome:R-HSA-2408536 Catalysis of the reaction: S-adenosyl-L-methionine + hydrogen selenide => S-adenosyl-L-homocysteine + methaneselenol. GO:0050672 negative regulation of lymphocyte proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050672 down-regulation of lymphocyte proliferation|downregulation of lymphocyte proliferation|down regulation of lymphocyte proliferation|inhibition of lymphocyte proliferation Any process that stops, prevents or reduces the rate or extent of lymphocyte proliferation. GO:0035010 encapsulation of foreign target biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035010 Events resulting in the formation of a multilayered cellular sheath surrounding an invader and thus preventing its development. This defense mechanism is often seen in insects in response to nematodes or parasitoids, which are too large to be phagocytosed by individual hemocytes. In some organisms the capsule is blackened due to melanization. GO:0098611 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0098611 GO:0035011 melanotic encapsulation of foreign target biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035011 Formation of a multilayered, melanized sheath of cells around a foreign invader. GO:0098612 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0098612 GO:0050670 regulation of lymphocyte proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050670 Any process that modulates the frequency, rate or extent of lymphocyte proliferation. GO:0050686 negative regulation of mRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050686 inhibition of mRNA processing|down regulation of mRNA processing|downregulation of mRNA processing|down-regulation of mRNA processing Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA processing. GO:0050687 negative regulation of defense response to virus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050687 down-regulation of antiviral response|downregulation of antiviral response|negative regulation of antiviral response|down regulation of antiviral response|inhibition of antiviral response Any process that stops, prevents or reduces the rate or extent of antiviral mechanisms, thereby facilitating viral replication. GO:0050684 regulation of mRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050684 Any process that modulates the frequency, rate or extent of mRNA processing, those processes involved in the conversion of a primary mRNA transcript into a mature mRNA prior to its translation into polypeptide. GO:0050685 positive regulation of mRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050685 up-regulation of mRNA processing|upregulation of mRNA processing|up regulation of mRNA processing|activation of mRNA processing|stimulation of mRNA processing Any process that activates or increases the frequency, rate or extent of mRNA processing. GO:1902438 response to vanadate(3-) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902438 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vanadate(3-) stimulus. GO:0050688 regulation of defense response to virus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050688 regulation of antiviral response Any process that modulates the frequency, rate or extent of the antiviral response of a cell or organism. GO:1902439 cellular response to vanadate(3-) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902439 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vanadate(3-) stimulus. GO:0050689 negative regulation of defense response to virus by host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050689 down regulation of antiviral response by host|inhibition of antiviral response by host|negative regulation of antiviral response by host|down-regulation of antiviral response by host|negative regulation by host of antiviral response|downregulation of antiviral response by host Any host process that results in the inhibition of antiviral immune response mechanisms, thereby facilitating viral replication. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:1902436 negative regulation of male mating behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902436 downregulation of male mating behavior|down regulation of male mating behavior|inhibition of male mating behavior|down-regulation of male mating behavior Any process that stops, prevents or reduces the frequency, rate or extent of male mating behavior. GO:0035009 negative regulation of melanization defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035009 downregulation of melanization defense response|down-regulation of melanization defense response|inhibition of melanization defense response|negative regulation of melanization defence response|down regulation of melanization defense response Any process that reduces the rate or extent of the melanization defense response. This regulation is critical to limit melanization to the site of injury or infection. GO:1902437 positive regulation of male mating behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902437 upregulation of male mating behavior|activation of male mating behavior|up-regulation of male mating behavior|up regulation of male mating behavior Any process that activates or increases the frequency, rate or extent of male mating behavior. GO:1902434 sulfate import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902434 sulphate import into cell|sulfate import into cell The directed movement of sulfate from outside of a cell, across the plasma membrane and into the cytosol. GO:1902435 regulation of male mating behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902435 Any process that modulates the frequency, rate or extent of male mating behavior. GO:1902432 protein localization to division septum biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902432 protein localization in division septum|protein localisation in division septum|protein localisation to division septum A process in which a protein is transported to, or maintained in, a location within a division septum. GO:1902433 positive regulation of water channel activity involved in maintenance of lens transparency biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902433 activation of water channel activity involved in maintenance of lens transparency|up-regulation of aquaporin involved in preservation of lens transparency|aquaporin activation involved in maintenance of ocular lens transparency|up-regulation of aquaporin involved in maintenance of lens transparency|up-regulation of aquaporin involved in maintenance of ocular lens transparency|activation of water channel activity involved in preservation of lens transparency|up-regulation of water channel activity involved in preservation of lens transparency|aquaporin activation involved in maintenance of lens transparency|activation of water channel activity involved in maintenance of ocular lens transparency|up-regulation of water channel activity involved in maintenance of ocular lens transparency|activation of aquaporin involved in maintenance of lens transparency|upregulation of aquaporin involved in preservation of lens transparency|up-regulation of water channel activity involved in maintenance of lens transparency|upregulation of aquaporin involved in maintenance of ocular lens transparency|positive regulation of aquaporin involved in maintenance of lens transparency|positive regulation of water channel activity involved in preservation of lens transparency|up regulation of aquaporin involved in maintenance of lens transparency|up regulation of water channel activity involved in preservation of lens transparency|positive regulation of water channel activity involved in maintenance of ocular lens transparency|up regulation of aquaporin involved in preservation of lens transparency|upregulation of water channel activity involved in maintenance of lens transparency|up regulation of water channel activity involved in maintenance of ocular lens transparency|positive regulation of aquaporin involved in preservation of lens transparency|up regulation of aquaporin involved in maintenance of ocular lens transparency|positive regulation of aquaporin involved in maintenance of ocular lens transparency|upregulation of aquaporin involved in maintenance of lens transparency|upregulation of water channel activity involved in preservation of lens transparency|activation of aquaporin involved in preservation of lens transparency|activation of aquaporin involved in maintenance of ocular lens transparency|up regulation of water channel activity involved in maintenance of lens transparency|aquaporin activation involved in preservation of lens transparency|upregulation of water channel activity involved in maintenance of ocular lens transparency Any positive regulation of water channel activity that is involved in maintenance of lens transparency. GO:1902430 negative regulation of amyloid-beta formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902430 down regulation of beta-amyloid formation|inhibition of beta-amyloid formation|negative regulation of beta-amyloid formation|down-regulation of beta-amyloid formation|downregulation of beta-amyloid formation Any process that stops, prevents or reduces the frequency, rate or extent of amyloid-beta formation. GO:0060010 Sertoli cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060010 The process in which the cellular identity of Sertoli cells is acquired and determined. GO:1902431 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902431 GO:0060011 Sertoli cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060011 The multiplication or reproduction of Sertoli cells, resulting in the expansion of the Sertoli cell population. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules. GO:0035001 dorsal trunk growth, open tracheal system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035001 dorsal trunk growth Growth of epithelial tubes that originate from pits in an open tracheal system and grow towards each other to meet and form a continuous open tube called the dorsal trunk. The dorsal trunk extends from the anterior spiracle to the posterior spiracle of the larva and forms the main airway of the insect tracheal system. GO:0060012 synaptic transmission, glycinergic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060012 glycinergic synaptic transmission The vesicular release of glycine from a presynapse, across a chemical synapse, the subsequent activation of glycine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. GO:1902440 protein localization to mitotic spindle pole body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902440 protein localisation to mitotic spindle pole body|establishment of protein localization to mitotic spindle pole body|protein localization in mitotic spindle pole body|protein localisation in mitotic spindle pole body A process in which a protein is transported to, or maintained in, a location within a mitotic spindle pole body. GO:0060013 righting reflex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060013 righting response A reflex process in which an animal immediately tries to turn over after being placed in a supine position. GO:0035002 liquid clearance, open tracheal system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035002 tracheal liquid clearance The clearance of liquid from the epithelial tubes of an open tracheal system, shortly before the emergence of the larva, to generate an air-filled tubule system. GO:0035003 subapical complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035003 SAC The most apical region of the lateral plasma membrane of an invertebrate epithelial cell. The subapical complex lies above the zonula adherens and the septate junction, and is comparable to the position of the tight junction of vertebrate cells. GO:0060014 granulosa cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060014 The process in which a relatively unspecialized cell acquires the specialized features of a granulosa cell, a supporting cell for the developing female gamete in the ovary of mammals. GO:0035004 phosphatidylinositol 3-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035004 Reactome:R-HSA-9670433|Reactome:R-HSA-9028519|Wikipedia:Phosphoinositide_3-kinase|Reactome:R-HSA-1433514|Reactome:R-HSA-2045911 phosphoinositide 3-kinase activity Catalysis of the reaction: ATP + a phosphatidylinositol = ADP + a phosphatidylinositol 3-phosphate. This reaction is the addition of a phosphate group to phosphatidylinositol or one of its phosphorylated derivatives at the 3' position of the inositol ring. GO:0060015 granulosa cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060015 The cell fate commitment of precursor cells that will become granulosa cells. GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035005 MetaCyc:2.7.1.154-RXN|KEGG_REACTION:R05795|EC:2.7.1.154|RHEA:18373|Reactome:R-HSA-1676206|Reactome:R-HSA-1676109|Reactome:R-HSA-8868072|Reactome:R-HSA-1675928 C2-domain-containing phosphoinositide 3-kinase activity|ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 3-phosphotransferase activity|phosphatidylinositol 3-kinase activity, class I|phosphatidylinositol 3-kinase activity, class II|phosphatidylinositol 3-kinase, class I, catalyst activity|phosphatidylinositol-4-phosphate 3-kinase activity|type II phosphoinositide 3-kinase activity Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ADP + 2 H(+). GO:0060016 granulosa cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060016 The process whose specific outcome is the progression of a granulosa cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a granulosa cell fate. GO:0060017 parathyroid gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060017 The process whose specific outcome is the progression of the parathyroid gland over time, from its formation to the mature structure. The parathyroid gland is an organ specialised for secretion of parathyroid hormone. GO:0035006 melanization defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035006 melanization defence response The blackening of the wounded area of the cuticle or the surface of invading pathogens, parasites or parasitoids, resulting from a proteolytic cascade leading to the de novo synthesis and deposition of melanin. GO:0035007 regulation of melanization defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035007 regulation of melanization defence response Any process that affects the rate, extent or location of the melanization defense response during injury or invasion. GO:0060018 astrocyte fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060018 The commitment of a cells to a specific astrocyte fate and its restriction to develop only into an astrocyte. GO:0035008 positive regulation of melanization defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035008 up regulation of melanization defense response|activation of melanization defense response|stimulation of melanization defense response|up-regulation of melanization defense response|positive regulation of melanization defence response|upregulation of melanization defense response Any process that increases the rate or extent of the melanization defense response during injury or invasion. GO:0060019 radial glial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060019 The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the brain. Differentiation includes the processes involved in commitment of a cell to a specific fate. GO:0050682 AF-2 domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050682 Interacting selectively and non-covalently with the AF-2 domain of a protein, a highly conserved ligand-dependent transactivation domain which is essential for receptor-mediated transcriptional activation. GO:0050683 AF-1 domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050683 Interacting selectively and non-covalently with the AF-1 domain of a protein, a ligand-independent transactivation domain which is required for the full transcriptional activity of the receptor. GO:0050680 negative regulation of epithelial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050680 down-regulation of epithelial cell proliferation|inhibition of epithelial cell proliferation|down regulation of epithelial cell proliferation|downregulation of epithelial cell proliferation Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation. GO:0035000 oligosaccharyltransferase III complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035000 OSTCIII An oligosaccharyltransferase (OST) complex that contains the seven polypeptides found in OST complex I, plus heterotrimeric Sec61alpha-beta-gamma and the tetrameric TRAP complex. Of the three forms of mammalian OST complexes identified, the OSTIII complex has the strongest affinity for ribosomes. GO:0050681 androgen receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050681 AR binding Interacting selectively and non-covalently with an androgen receptor. GO:0050697 1,1,2-trichloroethene reductive dehalogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050697 MetaCyc:TCEREDCHLOR-RXN|UM-BBD_enzymeID:e0271 1,1,2-trichloroethylene reductive dehalogenase activity|TCE-reductive dehalogenase activity Catalysis of the reaction: trichloroethene + 2 H+ + 2 e- = HCl + 1,2-dichloroethene. GO:0050698 proteoglycan sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050698 proteoglycan sulphotransferase activity|proteoglycan sulfate transfer Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + proteoglycan = adenosine 3',5'-bisphosphate + proteoglycan sulfate. A proteoglycan is a glycoprotein whose carbohydrate units are glycosaminoglycans. GO:0050695 benzoylformate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050695 EC:4.1.1.7|MetaCyc:BENZOYLFORMATE-DECARBOXYLASE-RXN|UM-BBD_reactionID:r1049|RHEA:23368 benzoylformate carboxy-lyase activity|benzoylformate carboxy-lyase (benzaldehyde-forming)|phenylglyoxylate decarboxylase activity Catalysis of the reaction: benzoylformate = benzaldehyde + CO2. GO:0050696 trichloroethylene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050696 trichloroethylene degradation|trichloroethylene breakdown|trichloroethene catabolism|trichloroethene catabolic process|trichloroethylene catabolism The chemical reactions and pathways resulting in the breakdown of trichloroethylene, a toxic, colorless, photoreactive, chlorinated hydrocarbon liquid, commonly used as a metal degreaser and solvent. GO:0050699 WW domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050699 Interacting selectively and non-covalently with a WW domain of a protein, a small module composed of 40 amino acids and plays a role in mediating protein-protein interactions via proline-rich regions. GO:1902449 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902449 GO:1902447 negative regulation of shade avoidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902447 down regulation of shade avoidance|downregulation of shade avoidance|down-regulation of shade avoidance|inhibition of shade avoidance Any process that stops, prevents or reduces the frequency, rate or extent of shade avoidance. GO:1902448 positive regulation of shade avoidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902448 up regulation of shade avoidance|activation of shade avoidance|up-regulation of shade avoidance|upregulation of shade avoidance Any process that activates or increases the frequency, rate or extent of shade avoidance. GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902445 regulation of transport across mitochondrial membrane involved in programmed necrotic cell death Any regulation of mitochondrial membrane permeability that is involved in programmed necrotic cell death. GO:1902446 regulation of shade avoidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902446 Any process that modulates the frequency, rate or extent of shade avoidance. GO:1902443 negative regulation of ripoptosome assembly involved in necroptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902443 down-regulation of ripoptosome assembly involved in necroptosis|downregulation of ripoptosome assembly involved in necroptosis|negative regulation of ripoptosome assembly involved in necroptosis|down regulation of ripoptosome assembly involved in necroptosis|inhibition of ripoptosome assembly involved in necroptosis Any process that stops, prevents or reduces the frequency, rate or extent of ripoptosome assembly involved in a necroptotic process. GO:1902444 riboflavin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1902444 Interacting selectively and non-covalently with riboflavin. GO:1902441 protein localization to meiotic spindle pole body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902441 protein localisation in meiotic spindle pole body|protein localisation to meiotic spindle pole body|establishment of protein localization to meiotic spindle pole body|protein location to meiotic spindle pole body|protein localization in meiotic spindle pole body A process in which a protein is transported to, or maintained in, a location within a meiotic spindle pole body. GO:1902442 regulation of ripoptosome assembly involved in necroptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902442 regulation of ripoptosome assembly involved in necroptosis Any process that modulates the frequency, rate or extent of ripoptosome assembly involved in a necroptotic process. GO:0060001 minus-end directed microfilament motor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0060001 minus-end directed actin-filament motor activity|minus-end directed actin filament motor activity|pointed-end directed actin-filament motor activity Catalysis of movement along a microfilament towards the minus end, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP). The minus end of an actin filament is the end that does not preferentially add actin monomers. GO:1902450 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902450 GO:0060002 plus-end directed microfilament motor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0060002 plus-end directed actin filament motor activity|plus-end directed actin-filament motor activity|barbed-end directed actin-filament motor activity Catalysis of movement along a microfilament towards the plus end, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP). The plus end of an actin filament is the end that preferentially adds actin monomers. GO:1902451 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902451 GO:0060003 copper ion export biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060003 copper export The directed movement of copper ions out of a cell or organelle. GO:0060004 reflex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060004 Wikipedia:Reflex An automatic response to a stimulus beginning with a nerve impulse from a receptor and ending with the action of an effector such as a gland or a muscle. Signaling never reaches a level of consciousness. GO:0060005 vestibular reflex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060005 A reflex process in which a response to an angular or linear acceleration stimulus begins with an afferent nerve impulse from a receptor in the inner ear and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness. GO:0060006 angular vestibuloocular reflex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060006 A vestibular reflex by which a response to an angular acceleration stimulus begins with an afferent nerve impulse from a receptor in the semi-circular canal and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness. GO:0060007 linear vestibuloocular reflex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060007 A vestibular reflex by which a response to a linear acceleration stimulus begins with an afferent nerve impulse from a receptor in the otolith and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness. GO:0060008 Sertoli cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060008 The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules. GO:0060009 Sertoli cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060009 The process whose specific outcome is the progression of a Sertoli cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a Sertoli cell fate. GO:0050690 regulation of defense response to virus by virus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050690 viral regulation of antiviral response|regulation of antiviral response by virus|regulation by virus of antiviral response Any viral process that modulates the frequency, rate, or extent of the antiviral response of the host cell or organism. GO:0050693 LBD domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050693 ligand binding domain binding Interacting selectively and non-covalently with the LBD, the ligand binding domain found in nuclear receptors. In general, the LBDs consist of three layers comprised of twelve alpha-helices and several beta-strands that are organized around a lipophilic ligand-binding pocket. GO:0050694 galactose 3-O-sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050694 Gal-3-O-sulfotransferase activity|galactose 3-O-sulphotransferase activity Catalysis of the reaction: N-acetyllactosamine + 3'-phosphoadenosine 5'-phosphosulfate = 3-sulfo-N-acetyllactosamine + adenosine 3',5'-bisphosphate. N-acetyllactosamine residues are found in a number of different carbohydrate types. N-acetyllactosamine can also be written as Gal-beta-(1,4)-GlcNAc. GO:0050691 regulation of defense response to virus by host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050691 host regulation of antiviral response|regulation by host of antiviral response|regulation of antiviral response by host Any host process that modulates the frequency, rate, or extent of the antiviral response of a host cell or organism. GO:0050692 DNA binding domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050692 DBD binding Interacting selectively and non-covalently with the DBD, DNA binding domain, of a protein. GO:0098642 network-forming collagen trimer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098642 A collagen trimer that forms networks. GO:0001697 histamine-induced gastric acid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001697 The regulated release of gastric acid induced by the interaction of histamine with H2 type receptor receptors with subsequent activation of adenylate cyclase and elevation of intracellular cyclic AMP. GO:0001698 gastrin-induced gastric acid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001698 The regulated release of gastric acid induced by the interaction of gastrin with its receptor. GO:0098643 banded collagen fibril biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098643 A supramolecular assembly of fibrillar collagen complexes in the form of a long fiber (fibril) with transverse striations (bands). GO:0098640 integrin binding involved in cell-matrix adhesion biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098640 Any integrin binding that occurs as part of the process of cell-matrix adhesion. GO:0001699 acetylcholine-induced gastric acid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001699 The regulated release of gastric acid by parietal cells in response to acetylcholine. GO:0098641 cadherin binding involved in cell-cell adhesion biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098641 Any cadherin binding that occurs as part of the process of cell-cell adhesion. GO:0001693 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001693 GO:0001694 histamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001694 histamine anabolism|histamine synthesis|histamine formation|histamine biosynthesis The chemical reactions and pathways resulting in the formation of histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. GO:0001695 histamine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001695 histamine catabolism|histamine degradation|histamine breakdown The chemical reactions and pathways resulting in the breakdown of histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. GO:0001696 gastric acid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001696 hydrochloric acid secretion The regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion. GO:1902458 positive regulation of stomatal opening biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902458 up regulation of stomatal opening|upregulation of stomatal opening|up-regulation of stomatal opening|activation of stomatal opening Any process that activates or increases the frequency, rate or extent of stomatal opening. GO:0001690 obsolete cytoplasmic dynein light chain biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001690 cytoplasmic dynein light chain OBSOLETE. (Was not defined before being made obsolete). GO:1902459 positive regulation of stem cell population maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902459 upregulation of maintenance of pluripotency|up-regulation of stem cell maintenance|up regulation of maintenance of pluripotency|positive regulation of maintenance of pluripotency|upregulation of stem cell maintenance|activation of maintenance of pluripotency|up-regulation of maintenance of pluripotency|up regulation of stem cell maintenance|activation of stem cell maintenance Any process that activates or increases the frequency, rate or extent of stem cell population maintenance. GO:1902456 regulation of stomatal opening biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902456 Any process that modulates the frequency, rate or extent of stomatal opening. GO:0001691 pseudophosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001691 Maintains the phosphorylation state of certain molecules by associating with them and preventing them from associating with active phosphatases, and thus inhibiting the enzyme activity without interacting with the enzyme. Often pertains to proteins belonging to dual-specificity phosphatase family but lacking critical active site residues. GO:1902457 negative regulation of stomatal opening biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902457 downregulation of stomatal opening|down regulation of stomatal opening|inhibition of stomatal opening|down-regulation of stomatal opening Any process that stops, prevents or reduces the frequency, rate or extent of stomatal opening. GO:0001692 histamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001692 histamine metabolism The chemical reactions and pathways involving histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. GO:0060030 dorsal convergence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060030 The directed migration of individual cells and small groups of cells toward the dorsal midline during gastrulation. This process does not require cell rearrangement. GO:1902454 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902454 GO:1902455 negative regulation of stem cell population maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902455 down-regulation of stem cell maintenance|down regulation of maintenance of pluripotency|inhibition of stem cell maintenance|downregulation of maintenance of pluripotency|negative regulation of maintenance of pluripotency|down-regulation of maintenance of pluripotency|down regulation of stem cell maintenance|downregulation of stem cell maintenance|inhibition of maintenance of pluripotency Any process that stops, prevents or reduces the frequency, rate or extent of stem cell population maintenance. GO:0060031 mediolateral intercalation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060031 The interdigitation of cells along the mediolateral axis during gastrulation. GO:0060032 notochord regression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060032 The developmental process in which the stucture of the notochord is destroyed in an embryo. GO:1902452 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902452 GO:0060033 anatomical structure regression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060033 tissue death|histolysis The developmental process in which an anatomical stucture is destroyed as a part of its normal progression. GO:1902453 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902453 GO:1902461 negative regulation of mesenchymal stem cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902461 down regulation of MSC proliferation|downregulation of mesenchymal stem cell proliferation|downregulation of MSC proliferation|down-regulation of mesenchymal stem cell proliferation|down-regulation of MSC proliferation|negative regulation of MSC proliferation|inhibition of mesenchymal stem cell proliferation|inhibition of MSC proliferation|down regulation of mesenchymal stem cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell proliferation. GO:0060034 notochord cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060034 The process in which relatively unspecialized cells acquire specialized structural and/or functional features cells that make up the notochord. Differentiation includes the processes involved in commitment of a cell to a notochord cell fate. GO:0060035 notochord cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060035 The process whose specific outcome is the progression of a notochord cell over time, from its formation to its mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. GO:1902462 positive regulation of mesenchymal stem cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902462 upregulation of MSC proliferation|up regulation of mesenchymal stem cell proliferation|activation of mesenchymal stem cell proliferation|up regulation of MSC proliferation|activation of MSC proliferation|positive regulation of MSC proliferation|up-regulation of mesenchymal stem cell proliferation|up-regulation of MSC proliferation|upregulation of mesenchymal stem cell proliferation Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell proliferation. GO:0060036 notochord cell vacuolation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060036 The assembly and arrangement of a vacuole within a cell of the notochord. GO:1902460 regulation of mesenchymal stem cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902460 regulation of MSC proliferation Any process that modulates the frequency, rate or extent of mesenchymal stem cell proliferation. GO:0060037 pharyngeal system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060037 The process whose specific outcome is the progression of the pharyngeal system over time, from its formation to the mature structure. The pharyngeal system is a transient embryonic complex that is specific to vertebrates. It comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the stucture it contributes to are forming: the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear. GO:0060038 cardiac muscle cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060038 cardiac myocyte proliferation|cardiomyocyte proliferation|heart muscle cell proliferation The expansion of a cardiac muscle cell population by cell division. GO:0060039 pericardium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060039 The process whose specific outcome is the progression of the pericardium over time, from its formation to the mature structure. The pericardium is a double-walled sac that contains the heart and the roots of the aorta, vena cava and the pulmonary artery. GO:0098648 collagen anchoring fibril biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098648 A specialised collagen fibril that functions as an anchor, binding to other collagen structures. GO:0098649 obsolete response to peptidyl-dipeptidase A inhibitor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098649 response to ACE inhibitor|response to angiotensin-converting enzyme inhibitor OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidyl-dipeptidase A inhibitor stimulus. GO:0098646 collagen sheet biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098646 collagen hexagonal network A protein complex that consists of collagen triple helices associated to form a sheet-like network. GO:0098647 collagen beaded filament biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098647 beads on a string A supramolecular assembly of collagen trimers with a 'beads on a string'-like structure. GO:0098644 complex of collagen trimers biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098644 Supramolecular collagen assembly|Supramolecular aggregate of collagen A complex of collagen trimers such as a fibril or collagen network. GO:0098645 collagen network biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098645 A supramolecular complex that consists of collagen triple helices associated to form a network. GO:0098653 centromere clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098653 kinetochore clustering The process by which centromeres/kinetochores become localized to clusters. GO:0098654 CENP-A recruiting complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098654 MIS18 complex A protein complex that includes Mis16(Yippee family) and/or Mis18 (WD repeat) subunits that is involved in the deposition of centromere specific (CENP-A containing) nucleosomes at the centromere. CHEBI:144784 omega-hydroxy-ultra-long chain fatty acylceramide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_144784 GO:0098651 basement membrane collagen trimer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098651 Any collagen timer that is part of a basement membrane. GO:0098652 collagen type VII anchoring fibril biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098652 An antiparallel dimer of two collagen VII trimers, one end of which is embedded in the lamina densa while the other end attaches to banded collagen fibrils in the dermis. CHEBI:144785 omega-linoleoyloxy-O-ultra-long chain acylceramide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_144785 GO:0098650 peptidyl-proline 4-dioxygenase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098650 Interacting selectively and non-covalently with a peptidyl-proline 4-dioxygenase. GO:1902469 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902469 GO:1902467 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902467 GO:1902468 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902468 GO:1902465 negative regulation of histone H3-K27 trimethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902465 inhibition of histone H3-K27 trimethylation|down regulation of histone H3-K27 trimethylation|downregulation of histone H3-K27 trimethylation|down-regulation of histone H3-K27 trimethylation Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K27 trimethylation. GO:1902466 positive regulation of histone H3-K27 trimethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902466 up-regulation of histone H3-K27 trimethylation|upregulation of histone H3-K27 trimethylation|up regulation of histone H3-K27 trimethylation|activation of histone H3-K27 trimethylation Any process that activates or increases the frequency, rate or extent of histone H3-K27 trimethylation. GO:0060020 Bergmann glial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060020 The process in which neuroepithelial cells of the neural tube give rise to Brgmann glial cells, specialized bipotential progenitors cells of the cerebellum. Differentiation includes the processes involved in commitment of a cell to a specific fate. GO:0060021 roof of mouth development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060021 palatum development The biological process whose specific outcome is the progression of the roof of the mouth from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The roof of the mouth is the partition that separates the nasal and oral cavities. GO:1902463 protein localization to cell leading edge biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902463 protein localisation to cell leading edge|protein localization in cell leading edge|protein localisation in cell leading edge A process in which a protein is transported to, or maintained in, a location within a cell leading edge. GO:1902464 regulation of histone H3-K27 trimethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902464 Any process that modulates the frequency, rate or extent of histone H3-K27 trimethylation. GO:0060022 hard palate development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060022 palatum durum development The biological process whose specific outcome is the progression of the hard palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The hard palate is the anterior portion of the palate consisting of bone and mucous membranes. GO:0060023 soft palate development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060023 palatum molle development|velum palatum development The biological process whose specific outcome is the progression of the soft palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The soft palate is the posterior portion of the palate extending from the posterior edge of the hard palate. GO:1902472 regulation of mitotic cytokinesis, site selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902472 Any process that modulates the frequency, rate or extent of mitotic cytokinesis, site selection. GO:1902473 regulation of protein localization to synapse biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902473 regulation of protein localisation to synapse Any process that modulates the frequency, rate or extent of protein localization to synapse. GO:0060024 rhythmic synaptic transmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060024 Any process involved in the generation of rhythmic, synchronous synaptic inputs in a neural circuit. GO:1902470 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902470 GO:0060025 regulation of synaptic activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060025 Any process that modulates the frequency, rate or extent of synaptic activity, the controlled release of neurotransmitters into the synaptic cleft and their subsequent detection by a postsynaptic cell. GO:0060026 convergent extension biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060026 Wikipedia:Convergent_extension The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis. GO:1902471 regulation of mitotic actomyosin contractile ring localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902471 Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring localization. GO:0060027 convergent extension involved in gastrulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060027 The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis usually resulting in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm. GO:0060028 convergent extension involved in axis elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060028 The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis contributing to the lengthening of the axis of an organism. GO:0060029 convergent extension involved in organogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060029 The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis contribution to the shaping of an organ. GO:0098659 inorganic cation import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098659 inorganic cation import into cell The directed movement of inorganic cations from outside of a cell, across the plasma membrane and into the cytosol. GO:0098657 import into cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098657 uptake The directed movement of some substance from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis. GO:0098658 inorganic anion import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098658 inorganic anion import into cell The directed movement of inorganic anions from outside of a cell, across the plasma membrane and into the cytosol. GO:0098655 cation transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098655 ATP hydrolysis coupled cation transmembrane transport The process in which a cation is transported across a membrane. GO:0098656 anion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098656 ATP hydrolysis coupled anion transmembrane transport The process in which an anion is transported across a membrane. GO:0098620 seryl-selenocysteinyl-tRNA kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098620 Reactome:R-HSA-2408507 Catalysis of the reaction: Ser-tRNA(Sec) + ATP = Sep-tRNA(Sec) + ADP. GO:0001675 acrosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001675 acrosome formation The formation of the acrosome from the spermatid Golgi. GO:0001676 long-chain fatty acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001676 long-chain fatty acid metabolism The chemical reactions and pathways involving long-chain fatty acids, A long-chain fatty acid is a fatty acid with a chain length between C13 and C22. GO:0098621 phosphoseryl-selenocysteinyl-tRNA selenium transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098621 Reactome:R-HSA-2408555 Catalysis of the reaction: O-phosphoseryl-tRNA(Sec) + selenophosphoric acid + H2O => L-selenocysteinyl-tRNA(Sec) + 2 phosphoric acid. GO:0001677 formation of translation initiation ternary complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001677 translation initiation ternary complex assembly Formation of a complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator). GO:0001678 cellular glucose homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001678 cell glucose homeostasis A cellular homeostatic process involved in the maintenance of an internal steady state of glucose within a cell or between a cell and its external environment. CHEBI:144774 linoleoyl containing 1,2,3-triacyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_144774 GO:0001671 ATPase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001671 Reactome:R-HSA-5251955|Reactome:R-HSA-5251959 ATPase stimulator activity Binds to and increases the ATP hydrolysis activity of an ATPase. CHEBI:144775 delphinidin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_144775 CHEBI:144776 delphinidin 3-O-beta-D-glucoside betaine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_144776 GO:0001672 regulation of chromatin assembly or disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001672 regulation of chromatin assembly/disassembly Any process that modulates the frequency, rate or extent of chromatin assembly or disassembly. GO:0001673 male germ cell nucleus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001673 male germ-cell nucleus The nucleus of a male germ cell, a reproductive cell in males. CHEBI:144777 pelargonidin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_144777 CHEBI:144778 pelargonidin 3-O-beta-D-glucoside betaine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_144778 GO:0001674 female germ cell nucleus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001674 female germ-cell nucleus The nucleus of the female germ cell, a reproductive cell in females. GO:0060050 positive regulation of protein glycosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060050 positive regulation of protein amino acid glycosylation Any process that activates or increases the frequency, rate or extent of the glycosylation of one or more amino acid residues within a protein. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins. GO:1902478 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902478 GO:0060051 negative regulation of protein glycosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060051 negative regulation of protein amino acid glycosylation Any process that stops, prevents, or reduces the frequency, rate or extent of the glycosylation of one or more amino acid residues within a protein. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins. GO:0001670 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001670 GO:1902479 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902479 GO:0060052 neurofilament cytoskeleton organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060052 neurofilament cytoskeleton organisation|neurofilament cytoskeleton organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising neurofilaments and their associated proteins. GO:1902476 chloride transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902476 The process in which chloride is transported across a membrane. GO:1902477 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902477 GO:0060053 neurofilament cytoskeleton biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0060053 Intermediate filament cytoskeletal structure that is made up of neurofilaments. Neurofilaments are specialized intermediate filaments found in neurons. GO:1902474 positive regulation of protein localization to synapse biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902474 up-regulation of protein localization to synapse|up-regulation of protein localisation to synapse|upregulation of protein localization to synapse|upregulation of protein localisation to synapse|up regulation of protein localization to synapse|activation of protein localization to synapse|up regulation of protein localisation to synapse|activation of protein localisation to synapse|positive regulation of protein localisation to synapse Any process that activates or increases the frequency, rate or extent of protein localization to synapse. GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060054 Any process that activates or increases the rate or extent of epithelial cell proliferation, contributing to the restoration of integrity to a damaged tissue following an injury. GO:0060055 angiogenesis involved in wound healing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060055 Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to a damaged tissue, following an injury. GO:1902475 L-alpha-amino acid transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902475 The directed movement of L-alpha-amino acid across a membrane. GO:1902483 cytotoxic T cell pyroptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902483 cytotoxic T cell apoptosis|cytotoxic T lymphocyte apoptotic process|cytotoxic T-lymphocyte apoptosis|cytotoxic T-cell apoptotic process|cytotoxic T cell apoptotic process|cytotoxic T-cell apoptosis|cytotoxic T-lymphocyte apoptotic process|cytotoxic T lymphocyte apoptosis Any pyroptotic process in a cytotoxic T cell. GO:0060056 mammary gland involution biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060056 The tissue remodeling that removes differentiated mammary epithelia during weaning. GO:0060057 apoptotic process involved in mammary gland involution biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060057 apoptosis involved in mammary gland involution Any apoptotic process that triggers the activity of proteolytic caspases whose actions dismantle the mammary epithelial cells resulting in their programmed cell death. GO:1902484 Sertoli cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902484 Sertoli cell apoptosis Any apoptotic process in a Sertoli cell. GO:1902481 gamma-tubulin complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902481 gamma-tubulin complex formation The aggregation, arrangement and bonding together of a set of components to form a gamma-tubulin complex. GO:0060058 positive regulation of apoptotic process involved in mammary gland involution biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060058 positive regulation of apoptosis involved in mammary gland involution Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process of mammary epithelial cells during mammary gland involution. GO:1902482 regulatory T cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902482 regulatory T-lymphocyte apoptosis|regulatory T-cell apoptotic process|regulatory T-lymphocyte apoptotic process|regulatory T cell apoptosis|regulatory T lymphocyte apoptosis|regulatory T lymphocyte apoptotic process|regulatory T-cell apoptosis Any apoptotic process in a regulatory T cell. GO:0060059 embryonic retina morphogenesis in camera-type eye biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060059 The process in which the anatomical structure of the retina is generated and organized in a camera-type eye during the embryonic life stage. GO:1902480 protein localization to mitotic spindle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902480 protein localisation to mitotic spindle|protein localization in mitotic spindle|protein localisation in mitotic spindle A process in which a protein is transported to, or maintained in, a location within a mitotic spindle. GO:0098628 peptidyl-N-phospho-arginine dephosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098628 The removal of phosphate residues from peptidyl-N-phospho-arginine to form peptidyl-arginine. GO:0098629 trans-Golgi network membrane organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098629 A process which results in the assembly, arrangement of constituent parts, or disassembly of a trans-Golgi network membrane. GO:0098626 methylseleninic acid reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098626 Reactome:R-HSA-5263616 Catalysis of the reaction: NADPH + H+ + CH3SeO2H => NADP+ + CH3SeOH + H2O. GO:0098627 protein arginine phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098627 Catalysis of the reaction: protein arginine phosphate + H2O = protein arginine + phosphate. GO:0098624 3'-Phosphoadenylylselenate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098624 Reactome:R-HSA-2408548 PAPSe reductase activity Catalysis of the reaction: 3'-phosphoadenylylselenate + NADPH => adenosine 3',5'-bisphosphate + selenite + NADP+ + H+. GO:0001679 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001679 GO:0098625 methylselenol reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098625 Reactome:R-HSA-5263614 Catalysis of the reaction: NADPH + H+ + CH3SeOH => NADP+ + CH3SeH + H2O. GO:0098622 selenodiglutathione-disulfide reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098622 Reactome:R-HSA-2408542|RHEA:34927 Catalysis of the reaction: H+ + selenodiglutathione + NADPH => gluthathioselenol + glutathione + NADP+. GO:0098623 selenite reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098623 Reactome:R-HSA-2408558 Catalysis of the reaction: SeO3(2-) + 3NADPH + 5H+ = H2Se + 3NADP+ + 3H2O. GO:0001686 obsolete axonemal dynein light chain biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001686 axonemal dynein light chain OBSOLETE. (Was not defined before being made obsolete). GO:0098631 cell adhesion mediator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098631 protein binding involved in cell adhesion|cell adhesion molecule The binding by a cell-adhesion protein on a cell surface to an adhesion molecule on another cell surface, to mediate adhesion of the cell to the external substrate or to another cell. GO:0098632 cell-cell adhesion mediator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098632 protein binding involved in cell-cell adhesion|cell-cell adhesion molecule The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to another cell. GO:0001687 obsolete cytoplasmic dynein heavy chain biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001687 cytoplasmic dynein heavy chain OBSOLETE. (Was not defined before being made obsolete). GO:0001688 obsolete cytoplasmic dynein intermediate chain biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001688 cytoplasmic dynein intermediate chain OBSOLETE. (Was not defined before being made obsolete). GO:0001689 obsolete cytoplasmic dynein intermediate light chain biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001689 cytoplasmic dynein intermediate light chain OBSOLETE. (Was not defined before being made obsolete). GO:0098630 aggregation of unicellular organisms biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098630 aggregation of single cell organisms The clustering together of unicellular organisms in suspension form aggregates. GO:0001682 tRNA 5'-leader removal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001682 tRNA 5' leader removal Generation of the mature 5'-end of the tRNA, usually via an endonucleolytic cleavage by RNase P. GO:0001683 obsolete axonemal dynein heavy chain biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001683 axonemal dynein heavy chain OBSOLETE. (Was not defined before being made obsolete). GO:0001684 obsolete axonemal dynein intermediate chain biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001684 axonemal dynein intermediate chain OBSOLETE. (Was not defined before being made obsolete). GO:0001685 obsolete axonemal dynein intermediate light chain biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001685 axonemal dynein intermediate light chain OBSOLETE. (Was not defined before being made obsolete). GO:0001680 tRNA 3'-terminal CCA addition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001680 MetaCyc:TRNA-CYTIDYLYLTRANSFERASE-RXN|KEGG_REACTION:R09382 transfer ribonucleate adenylyltransferase activity|tRNA-nucleotidyltransferase activity|transfer-RNA nucleotidyltransferase activity|-C-C-A pyrophosphorylase activity|ribonucleic cytidylic cytidylic adenylic pyrophosphorylase activity|transfer ribonucleate cytidylyltransferase activity|tRNA CCA-diphosphorylase activity|tRNA cytidylyltransferase activity|CTP(ATP):tRNA nucleotidyltransferase activity|transfer ribonucleate nucleotidyltransferase activity|ATP(CTP):tRNA nucleotidyltransferase activity|CCA-adding enzyme, tRNA adenylyltransferase, tRNA cytidylyltransferase, tRNA CCA-pyrophosphorylase activity|CCA-adding enzyme activity|CTP:tRNA cytidylyltransferase activity|ribonucleic cytidylyltransferase activity|transfer ribonucleate adenyltransferase activity|transfer ribonucleic adenylyl (cytidylyl) transferase activity|CCA tRNA nucleotidyltransferase activity|transfer ribonucleic-terminal trinucleotide nucleotidyltransferase activity|transfer RNA adenylyltransferase activity|ATP(CTP)-tRNA nucleotidyltransferase activity|tRNA adenylyl(cytidylyl)transferase activity|transfer ribonucleic acid nucleotidyl transferase activity Post-transcriptional addition of the terminal 3' CCA sequence to a tRNA which does not encode this sequence within the primary transcript. CCA addition proceeds by the sequential addition of CTP, CTP, and then ATP to the 3' end of the tRNA, yielding a diphosphate with each nucleotide addition. GO:1902489 hepatoblast apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902489 hepatoblast apoptosis Any apoptotic process in a hepatoblast. GO:0001681 sialate O-acetylesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001681 EC:3.1.1.53|MetaCyc:SIALATE-O-ACETYLESTERASE-RXN sialate 9(4)-O-acetylesterase activity|N-acyl-O-acetylneuraminate O-acetylhydrolase activity|N-acetylneuraminate acetyltransferase activity Catalysis of the reaction: N-acetyl-O-acetylneuraminate (free or glycosidically bound) + H2O = N-acetylneuraminate + acetate. GO:0060040 retinal bipolar neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060040 The process in which a relatively unspecialized cell acquires specialized features of a bipolar cell, the last neuron to be generated in the retina. GO:1902487 protein localization to non-growing cell tip biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902487 protein localisation to non-growing cell tip|protein localisation in non-growing cell tip|protein localization in non-growing cell tip A process in which a protein is transported to, or maintained in, a location within a non-growing cell tip. GO:0060041 retina development in camera-type eye biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060041 retinal development|retina development in camera-style eye The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates. GO:0060042 retina morphogenesis in camera-type eye biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060042 retinogenesis|retina morphogenesis in camera-style eye The process in which the anatomical structure of the retina is generated and organized. GO:1902488 cholangiocyte apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902488 epithelial cell of bile duct apoptosis|epithelial cell of bile duct apoptotic process|cholangiocyte apoptosis Any apoptotic process in a cholangiocyte. GO:0060043 regulation of cardiac muscle cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060043 regulation of cardiomyocyte proliferation|regulation of heart muscle cell proliferation Any process that modulates the frequency, rate or extent of cardiac muscle cell proliferation. GO:1902485 L-cysteine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1902485 Interacting selectively and non-covalently with L-cysteine. GO:0060044 negative regulation of cardiac muscle cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060044 negative regulation of heart muscle cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell proliferation. GO:1902486 protein localization to growing cell tip biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902486 protein localisation to growing cell tip|protein localisation in growing cell tip|protein localization in growing cell tip A process in which a protein is transported to, or maintained in, a location within a growing cell tip. GO:0060045 positive regulation of cardiac muscle cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060045 positive regulation of heart muscle cell proliferation Any process that activates or increases the frequency, rate or extent of cardiac muscle cell proliferation. GO:1902494 catalytic complex biolink:CellularComponent go-plus goslim_metagenomics http://purl.obolibrary.org/obo/GO_1902494 enzyme complex A protein complex which is capable of catalytic activity. GO:1902495 transmembrane transporter complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902495 A transmembrane protein complex which enables the transfer of a substance from one side of a membrane to the other. GO:0060046 regulation of acrosome reaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060046 Any process that modulates the frequency, rate or extent of the acrosome reaction. GO:1902492 positive regulation of sperm capacitation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902492 up regulation of sperm activation|upregulation of sperm capacitation|upregulation of sperm activation|up-regulation of sperm capacitation|activation of sperm capacitation|up-regulation of sperm activation|activation of sperm activation|up regulation of sperm capacitation|positive regulation of sperm activation Any process that activates or increases the frequency, rate or extent of sperm capacitation. GO:0060047 heart contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060047 hemolymph circulation|heart beating|cardiac contraction The multicellular organismal process in which the heart decreases in volume in a characteristic way to propel blood through the body. GO:0011000 replication fork arrest at mating type locus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0011000 A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the mating type locus. GO:1902493 acetyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902493 A protein complex which is capable of acetyltransferase activity. GO:0060048 cardiac muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060048 heart muscle contraction Muscle contraction of cardiac muscle tissue. GO:1902490 regulation of sperm capacitation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902490 regulation of sperm activation Any process that modulates the frequency, rate or extent of sperm capacitation. GO:0060049 regulation of protein glycosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060049 regulation of protein amino acid glycosylation Any process that modulates the frequency, rate or extent of protein glycosylation. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins. GO:1902491 negative regulation of sperm capacitation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902491 down regulation of sperm capacitation|downregulation of sperm activation|inhibition of sperm capacitation|down regulation of sperm activation|inhibition of sperm activation|down-regulation of sperm capacitation|negative regulation of sperm activation|down-regulation of sperm activation|downregulation of sperm capacitation Any process that stops, prevents or reduces the frequency, rate or extent of sperm capacitation. GO:0098639 collagen binding involved in cell-matrix adhesion biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098639 Any collagen binding that occurs as part of cell-matrix adhesion. GO:0098637 protein complex involved in cell-matrix adhesion biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098637 Any protein complex that is capable of carrying out some part of the process of cell-matrix adhesion. GO:0098638 laminin binding involved in cell-matrix adhesion biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098638 Any laminin protein binding that occurs as part of cell-matrix adhesion. GO:0098635 protein complex involved in cell-cell adhesion biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098635 Any protein complex that is capable of carrying out some part of the process of cell-cell adhesion. GO:0098636 protein complex involved in cell adhesion biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098636 cell adhesion complex Any protein complex that is capable of carrying out some part of the process of cell adhesion to the cell matrix or to another cell. GO:0098633 collagen fibril binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098633 Interacting selectively and non-covalently with a collagen fibril. GO:0098634 cell-matrix adhesion mediator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098634 protein binding involved in cell-matrix adhesion|cell-matrix adhesion molecule The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to the extracellular matrix. OBA:VT1000784 circulatory system trait biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_VT1000784 The quality when measured in circulatory system. OBA:VT1000781 nervous/sensory system trait biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_VT1000781 The quality when measured in nervous system. CHEBI:86570 (5alpha)-cholestan-3beta-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86570 OPL:0000151 promastigote stage biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OPL_0000151 A parasite lifecycle stage of Trypanosomatids. In this stage, the flagellum is found anterior of nucleus and flagellum not attached to the cell body. The kinetoplast is located in front of the nucleus, near the anterior end of the body. (Wikipedia: Trypanosomatid) OPL:0000156 Schistosoma japonicum lifecycle stage biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OPL_0000156 A lifecycle stage of Schistosoma japonicum. OPL:0000154 Glossina salivary gland biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OPL_0000154 A salivary gland that is a part of or originated from a tsetse fly of genus Glossina. PO:0000372 metaxylem biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000372 portion of metaxylem tissue (exact)|後生木部 (Japanese, exact)|metaxilema (Spanish, exact) A portion of primary xylem (PO:0005849) tissue that has as part one or more metaxylem tracheary elements (PO:0025576) embedded in parenchyma (PO:0005421) tissue and may contain xylem fiber cells (PO:0000274). CHEBI:37606 octadecene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37606 CHEBI:37607 trans-octadec-9-ene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37607 CHEBI:86564 4-guanidinobutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86564 CHEBI:13611 4-hydroxy carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_13611 OPL:0000149 metacyclic trypomastigote stage biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OPL_0000149 A trypomastigote stage of Trypanosoma species which are nondividing forms resistant to mammalian complement that have the capacity to infect mammalian cells. CHEBI:13614 6,7-dihydropteridines biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_13614 CHEBI:37604 cis-octadec-9-ene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37604 CHEBI:37605 octadec-9-ene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37605 CHEBI:37602 allenes biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37602 CHEBI:13610 3beta-hydroxysterol ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_13610 GO:0035092 sperm chromatin condensation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035092 The progressive compaction of the spermatid chromatin so that it reaches a level of condensation that is not compatible with nuclear activities such as transcription or DNA replication. GO:0035093 spermatogenesis, exchange of chromosomal proteins biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035093 somatic histone exchange|somatic histone replacement The replacement of somatic histones within sperm chromatin with sperm-specific histones or protamines with unique DNA-binding properties, resulting in condensation of the sperm chromatin. GO:0035094 response to nicotine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035094 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus. GO:0035095 behavioral response to nicotine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035095 behavioural response to nicotine Any process that results in a change in the behavior of an organism as a result of a nicotine stimulus. GO:0035096 larval midgut cell programmed cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035096 larval midgut cell death|programmed cell death of larval midgut cells The stage-specific programmed cell death of cells of the larval midgut, during histolysis of the larval organ. GO:0035097 histone methyltransferase complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0035097 A multimeric complex that is able to catalyze the addition of methyl groups to histone proteins. GO:0035098 ESC/E(Z) complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035098 Extra Sex Combs/Enhancer of Zeste complex|PRC2 complex A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Drosophila the core subunits of the complex include ESC, E(Z), CAF1 (NURF-55) and SU(Z)12. In mammals the core subunits of the complex include EED, EZH2, SUZ12 and RBBP4. GO:0035099 hemocyte migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035099 hemocyte cell migration|arthropod blood cell migration The directed movement of a hemocyte within the embryo. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. In Drosophila, embryonic hemocytes originate from the head mesoderm as a cluster of cells. The cluster splits into two and one group of cells crosses the amnioserosa. Both populations then spread toward the middle of the embryo and then disperse evenly throughout the embryo. GO:0050602 monoprenyl isoflavone epoxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050602 EC:1.14.99.34|MetaCyc:1.14.99.34-RXN monoprenyl isoflavone monooxygenase activity|7-O-methylluteone,NADPH:O2 oxidoreductase activity|7-O-methylluteone:O2 oxidoreductase activity Catalysis of the reaction: O2 + NADPH + H+ + 7-O-methylluteone = H2O + NADP+ + dihydrofurano derivatives. GO:0050603 thiophene-2-carbonyl-CoA monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050603 EC:1.14.99.35|RHEA:18929|MetaCyc:1.14.99.35-RXN|UM-BBD_reactionID:r1235|KEGG_REACTION:R05742 thiophene-2-carboxyl-CoA monooxygenase activity|thiophene-2-carboxyl-CoA dehydrogenase activity|thiophene-2-carboxyl-CoA hydroxylase activity|thiophene-2-carbonyl-CoA, hydrogen-donor:oxygen oxidoreductase activity Catalysis of the reaction: AH(2) + O(2) + thiophene-2-carbonyl-CoA = 5-hydroxythiophene-2-carbonyl-CoA + A + H(2)O + H(+). GO:0050600 myristoyl-CoA 11-(E) desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050600 RHEA:46396|EC:1.14.19.24|MetaCyc:1.14.99.31-RXN n-tetradecanoyl-CoA,NADPH:O2 oxidoreductase [11-(E) desaturating]|n-tetradecanoyl-CoA,NAD(P)H:O2 oxidoreductase [11-(E) desaturating] Catalysis of the reaction: myristoyl-CoA + NAD(P)H + H+ + O2 = (E)-11-tetradecenoyl-CoA + NAD(P)+ + 2 H2O. GO:0035090 maintenance of apical/basal cell polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035090 Retaining the established polarization of a cell along its apical/basal axis. GO:0035091 phosphatidylinositol binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035091 phosphoinositide binding Interacting selectively and non-covalently with any inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives. GO:0050601 myristoyl-CoA 11-(Z) desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050601 EC:1.14.19.5|MetaCyc:1.14.99.32-RXN|RHEA:25852 n-tetradecanoyl-CoA,NADPH:O2 oxidoreductase [11-(Z) desaturating]|n-tetradecanoyl-CoA,NAD(P)H:O2 oxidoreductase [11-(Z) desaturating] Catalysis of the reaction: myristoyl-CoA + NAD(P)H + H+ + O2 = (Z)-11-tetradecenoyl-CoA + NAD(P)+ + 2 H2O. GO:0050606 4-carboxy-2-hydroxymuconate semialdehyde hemiacetal dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050606 KEGG_REACTION:R04279|RHEA:29587|MetaCyc:1.2.1.45-RXN|EC:1.1.1.312 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase activity|alpha-hydroxy-gamma-carboxymuconic epsilon-semialdehyde dehydrogenase activity|4-carboxy-2-hydroxy-cis,cis-muconate-6-semialdehyde:NADP(+) oxidoreductase activity|2-hydroxy-4-carboxymuconate 6-semialdehyde dehydrogenase activity Catalysis of the reaction: 4-carboxy-2-hydroxymuconate semialdehyde hemiacetal + NADP(+) = 2-oxo-2H-pyran-4,6-dicarboxylate + H(+) + NADPH. PO:0000349 epidermal initial cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000349 epidermal initial (exact)|célula inicial de la epidermis (Spanish, exact)|表皮始原細胞 (Japanese, exact) An initial cell (PO:0004011) that is part of an epidermis (PO:0005679) and gives rise to specialized cell types of the epidermis. GO:0050607 mycothiol-dependent formaldehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050607 RHEA:28502|EC:1.1.1.306|MetaCyc:1.2.1.66-RXN NAD/factor-dependent formaldehyde dehydrogenase activity|formaldehyde:NAD+ oxidoreductase (mycothiol-formylating) Catalysis of the reaction: formaldehyde + mycothiol + NAD+ = S-formylmycothiol + NADH + H+. OPL:0000131 Trypanosoma cruzi metacyclic trypomastigote stage biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OPL_0000131 A metacyclic trypomastigote stage in the lifecycle of Trypanosoma cruzi that occurs in a vertebrate host. GO:0050604 taxadiene 5-alpha-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050604 EC:1.14.99.37|MetaCyc:1.14.99.37-RXN|KEGG_REACTION:R06306|RHEA:14049 taxadiene 5alpha-hydroxylase activity|taxadiene 5a-hydroxylase activity|taxa-4,11-diene,hydrogen-donor:oxygen oxidoreductase (5alpha-hydroxylating) Catalysis of the reaction: AH(2) + O(2) + taxa-4,11-diene = A + H(2)O + taxa-4(20),11-dien-5alpha-ol. GO:0050605 superoxide reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050605 EC:1.15.1.2|MetaCyc:1.15.1.2-RXN|RHEA:21324 rubredoxin:superoxide oxidoreductase activity|desulfoferrodoxin activity|neelaredoxin activity Catalysis of the reaction: superoxide + reduced rubredoxin + 2 H+ = H2O2 + rubredoxin. GO:0050608 vanillin dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050608 KEGG_REACTION:R05699|MetaCyc:1.2.1.67-RXN|EC:1.2.1.67|RHEA:13309 vanillin:NAD+ oxidoreductase activity Catalysis of the reaction: H(2)O + NAD(+) + vanillin = 2 H(+) + NADH + vanillate. GO:0050609 phosphonate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050609 UM-BBD_reactionID:r1055|RHEA:13173|EC:1.20.1.1|KEGG_REACTION:R05746|MetaCyc:1.20.1.1-RXN NAD:phosphite oxidoreductase activity|phosphite dehydrogenase activity|phosphonate:NAD+ oxidoreductase activity|NAD-dependent phosphite dehydrogenas activity Catalysis of the reaction: H(2)O + NAD(+) + phosphonate = 2 H(+) + NADH + phosphate. GO:0035089 establishment of apical/basal cell polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035089 The specification and formation of the polarity of a cell along its apical/basal axis. CHEBI:13643 glycol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_13643 GO:0035081 induction of programmed cell death by hormones biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035081 Any process induced by hormones that directly activates any of the steps required for programmed cell death. GO:0035082 axoneme assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035082 ciliary axoneme assembly|cilium axoneme biogenesis|flagellar axoneme assembly|axoneme biogenesis|flagellum axoneme assembly|cilium axoneme assembly The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements. GO:0035083 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035083 GO:0035084 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035084 GO:0035085 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035085 GO:0035086 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035086 GO:0035087 siRNA loading onto RISC involved in RNA interference biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035087 RNA interference, siRNA loading onto RISC The transfer of small interfering RNA molecules (siRNAs) from the Dicer family of enzymes that cleave the double-stranded RNA, onto the nuclease-containing RNA-initiated silencing complex (RISC), in the context of RNA interference. UBERON:8000006 left side of back biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_8000006 Left part of the organism dorsal to a horizontal plane and bounded on one side by the same transverse plane. UBERON:8000007 right side of back biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_8000007 Right part of the organism dorsal to a horizontal plane and bounded on one side by the same transverse plane. GO:0035088 establishment or maintenance of apical/basal cell polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035088 Any cellular process that results in the specification, formation or maintenance polarization of a cell's architecture along its apical/basal axis so that the apical and basal regions of the cell have different membrane, extracellular matrix and sub-membrane cellular components. PO:0000351 guard mother cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000351 célula madre de la célula guardiana (Spanish, exact)|孔辺母細胞 (Japanese, exact) A shoot epidermal cell that divides to produce the guard cells. GO:0050610 methylarsonate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050610 MetaCyc:1.20.4.2-RXN|KEGG_REACTION:R05748|RHEA:15969|EC:1.20.4.2|UM-BBD_reactionID:r0837|Reactome:R-HSA-5696230 glutathione:methylarsonate oxidoreductase activity|MMA(V) reductase activity Catalysis of the reaction: 2 glutathione + H(+) + methylarsonate = glutathione disulfide + H(2)O + methylarsonous acid. PO:0000332 epidermal pavement cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000332 表皮被蓋細胞 (Japanese, exact)|célula del pavimento epidermal (Spanish, exact) A shoot epidermal cell that is relatively unspecialized at maturity. GO:0050613 delta14-sterol reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050613 Reactome:R-HSA-194674|EC:1.3.1.70|RHEA:18561|Reactome:R-HSA-194698|MetaCyc:1.3.1.70-RXN C-14 sterol reductase activity|4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol:NADP+ delta14-oxidoreductase activity|sterol C14-reductase activity|sterol C-14 reductase activity|D14-sterol reductase activity Catalysis of the reaction: NADP+ + 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol = NADPH + H+ + 4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol. GO:0050614 delta24-sterol reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050614 Reactome:R-HSA-196417|Reactome:R-HSA-6807064|EC:1.3.1.72|RHEA:13685|MetaCyc:1.3.1.72-RXN lanosterol Delta(24)-reductase activity|sterol:NADP+ delta24-oxidoreductase activity|lanosterol delta24-reductase activity|D24-sterol reductase activity Catalysis of the reaction: NADP+ + 5-alpha-cholest-7-en-3-beta-ol = NADPH + H+ + 5-alpha-cholesta-7,24-dien-3-beta-ol. GO:0050611 arsenate reductase (azurin) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050611 UM-BBD_reactionID:r0634|RHEA:18701|EC:1.20.9.1|MetaCyc:1.20.98.1-RXN arsenite:azurin oxidoreductase activity|arsenite oxidase activity Catalysis of the reaction: H(2)O + arsenite + 2 oxidized azurin = 2 H(+) + 2 reduced azurin + arsenate. GO:0050612 arsenate reductase (donor) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050612 RHEA:18449|KEGG_REACTION:R05752|MetaCyc:1.20.99.1-RXN|EC:1.20.99.1 arsenate:(acceptor) oxidoreductase activity|arsenate:acceptor oxidoreductase activity Catalysis of the reaction: A + arsenite + H(2)O = AH(2) + arsenate + 2 H(+). GO:0035080 heat shock-mediated polytene chromosome puffing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035080 The decondensing (loosening) and swelling of the chromosomal sites of heat shock genes on polytene chromosomes in response to a heat shock stimulus. GO:0050617 15,16-dihydrobiliverdin:ferredoxin oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050617 MetaCyc:1.3.7.2-RXN|RHEA:10168|EC:1.3.7.2 PebA Catalysis of the reaction: 15,16-dihydrobiliverdin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin. GO:0050618 phycoerythrobilin:ferredoxin oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050618 MetaCyc:1.3.7.3-RXN|EC:1.3.7.3|RHEA:22092 PebB|(3Z)-phycoerythrobilin:ferredoxin oxidoreductase activity Catalysis of the reaction: (3Z)-phycoerythrobilin + oxidized ferredoxin = 15,16-dihydrobiliverdin + reduced ferredoxin. GO:0050615 1,2-dihydrovomilenine reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050615 KEGG_REACTION:R05879|EC:1.3.1.73|RHEA:12320|MetaCyc:1.3.1.73-RXN 17-O-acetylnorajmaline:NADP+ oxidoreductase activity Catalysis of the reaction: 17-O-acetylnorajmaline + NADP(+) = 1,2-dihydrovomilenine + H(+) + NADPH. GO:0050616 secologanin synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050616 EC:1.14.19.62|MetaCyc:1.3.3.9-RXN|RHEA:20585 loganin:oxygen oxidoreductase (ring-cleaving) Catalysis of the reaction: loganin + NADPH + H+ + O2 = secologanin + NADP+ + 2 H2O. CHEBI:13637 flavanone 7-O-beta-D-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_13637 GO:0050619 phytochromobilin:ferredoxin oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050619 MetaCyc:1.3.7.4-RXN|EC:1.3.7.4|RHEA:16377 (3Z)-phytochromobilin:ferredoxin oxidoreductase activity|PFB synthase activity|phytochromobilin synthase activity|HY2|P-Phi-B synthase activity|PPhiB synthase activity Catalysis of the reaction: (3Z)-phytochromobilin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin. GO:0035078 induction of programmed cell death by ecdysone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035078 Any process induced by the steroid hormone 20-hydroxyecdysone (ecdysone) that directly activates any of the steps required for programmed cell death. GO:0035079 polytene chromosome puffing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035079 The decondensing (loosening) and swelling of the chromosomal sites of target genes on polytene chromosomes following response to a stimulus, to facilitate sudden bursts of transcriptional activity in response to transient environmental signals. GO:0035070 salivary gland histolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035070 salivary gland regression The stage-specific break down of the larval salivary glands during Drosophila metamorphosis, to allow replacement of larval structures by tissues and structures that form the adult fly. GO:0035071 salivary gland cell autophagic cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035071 programmed cell death of salivary gland cells by autophagy|salivary gland cell death|salivary gland cell programmed cell death by autophagy|autophagic cell death of salivary gland cells The stage-specific programmed cell death of salivary gland cells during salivary gland histolysis. GO:0035072 ecdysone-mediated induction of salivary gland cell autophagic cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035072 ecdysone-mediated induction of programmed cell death of salivary gland cells by autophagy|ecdysone-mediated induction of salivary gland cell programmed cell death by autophagy|ecdysone-mediated induction of autophagic cell death of salivary gland cells Any process induced by ecdysone that directly activates salivary gland programmed cell death during salivary gland histolysis. GO:0035073 pupariation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035073 puparium biosynthesis|puparium formation The onset of prepupal development when the larval stops crawling, everts its spiracles and the larval cuticle becomes the puparium or pupal case that surrounds the organism for the duration of metamorphosis. GO:0035074 pupation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035074 Wikipedia:Pupa prepupal-pupal transition|head eversion The act of becoming a pupa, a resting stage in the life cycle of organisms with complete metamorphosis. This event marks the end of the prepupal period and the beginning of the pupal period. GO:0035075 response to ecdysone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035075 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ecdysone stimulus. GO:0035076 ecdysone receptor-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035076 ecdysone receptor-mediated signalling pathway The series of molecular signals generated by ecdysone binding to the ecdysone receptor complex. GO:0035077 ecdysone-mediated polytene chromosome puffing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035077 The decondensing (loosening) and swelling of the chromosomal sites of hormone-responsive genes on polytene chromosomes in response to increased production of the steroid hormone 20-hydroxyecdysone (ecdysone) in Drosophila larvae approaching pupation. GO:0050620 phycocyanobilin:ferredoxin oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050620 RHEA:15309|MetaCyc:1.3.7.5-RXN|EC:1.3.7.5 (3Z)-phycocyanobilin:ferredoxin oxidoreductase activity Catalysis of the reaction: (3Z)-phycocyanobilin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin. GO:0050621 tryptophan alpha,beta-oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050621 EC:1.3.3.10|KEGG_REACTION:R05317|RHEA:19901|MetaCyc:1.4.3.17-RXN tryptophan a,b-oxidase activity|L-tryptophan alpha,beta-dehydrogenase activity|L-tryptophan 2',3'-oxidase activity|L-tryptophan:oxygen alpha,beta-oxidoreductase activity Catalysis of the reaction: L-tryptophan + O(2) = alpha,beta-didehydrotryptophan + H(2)O(2) + H(+). GO:0050624 vomilenine reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050624 MetaCyc:1.5.1.32-RXN|RHEA:16409|EC:1.5.1.32|KEGG_REACTION:R05878 1,2-dihydrovomilenine:NADP+ oxidoreductase activity Catalysis of the reaction: 1,2-dihydrovomilenine + NADP(+) = H(+) + NADPH + vomilenine. GO:0050625 2-hydroxy-1,4-benzoquinone reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050625 UM-BBD_reactionID:r0667|MetaCyc:1.6.5.7-RXN|RHEA:12428|EC:1.6.5.7|KEGG_REACTION:R05399 NADH:2-hydroxy-1,4-benzoquinone oxidoreductase activity|2-hydroxy-1,4-benzoquinone:NADH oxidoreductase activity|1,2,4-trihydroxybenzene:NAD+ oxidoreductase activity|hydroxybenzoquinone reductase activity|1,2,4-trihydroxybenzene:NAD oxidoreductase activity Catalysis of the reaction: 2-hydroxy-1,4-benzoquinone + 2 H(+) + NADH = benzene-1,2,4-triol + NAD(+). GO:0050622 glycine dehydrogenase (cyanide-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050622 EC:1.4.99.5|MetaCyc:1.4.99.5-RXN|RHEA:15821 HCN synthase activity|hydrogen cyanide synthase activity|glycine:acceptor oxidoreductase (hydrogen-cyanide-forming) Catalysis of the reaction: glycine + 2 A = HCN + CO2 + 2 AH2. GO:0050623 berberine reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050623 MetaCyc:1.5.1.31-RXN|RHEA:21268|EC:1.5.1.31|KEGG_REACTION:R07169 (R)-tetrahydroberberine:NADP+ oxidoreductase activity|(R)-canadine synthase activity Catalysis of the reaction: (R)-canadine + 2 NADP(+) = berberine + H(+) + 2 NADPH. GO:0050628 2-oxopropyl-CoM reductase (carboxylating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050628 UM-BBD_reactionID:r0854|MetaCyc:1.8.1.5-RXN|KEGG_REACTION:R05713|RHEA:16977|EC:1.8.1.5 NADPH:2-ketopropyl-coenzyme M oxidoreductase/carboxylase activity|2-KPCC activity|NADPH:2-(2-ketopropylthio)ethanesulfonate oxidoreductase/carboxylase activity|2-mercaptoethanesulfonate,acetoacetate:NADP+ oxidoreductase (decarboxylating) Catalysis of the reaction: acetoacetate + coenzyme M + NADP(+) = 2-oxopropyl-coenzyme M + CO(2) + NADPH. GO:0050629 tetrachloroethene reductive dehalogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050629 EC:1.21.99.5|MetaCyc:1.97.1.8-RXN|RHEA:20353 tetrachloroethene reductase activity|acceptor:trichloroethene oxidoreductase (chlorinating) Catalysis of the reaction: trichloroethene + chloride + acceptor = tetrachloroethene + reduced acceptor. GO:0050626 trimethylamine-N-oxide reductase (cytochrome c) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050626 Wikipedia:Trimethylamine_N-oxide_reductase|MetaCyc:1.7.2.3-RXN|RHEA:24236|EC:1.7.2.3 trimethylamine:cytochrome c oxidoreductase activity|TOR activity|TMAO reductase activity Catalysis of the reaction: trimethylamine + 2 (ferricytochrome c)-subunit + H2O = trimethylamine-N-oxide + 2 (ferrocytochrome c)-subunit + 2 H+. OPL:0000194 Phlebotominae midgut biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OPL_0000194 A midgut that is a part of or originated from a sand fly of genus Phlebotominae. GO:0050627 mycothione reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050627 MetaCyc:1.8.1.15-RXN|EC:1.8.1.15 mycothiol-disulfide reductase activity|mycothiol:NAD(P)+ oxidoreductase activity Catalysis of the reaction: NAD(P)+ + mycothiol = NAD(P)H + H+ + mycothione. GO:0035067 negative regulation of histone acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035067 downregulation of histone acetylation|down-regulation of histone acetylation|inhibition of histone acetylation|down regulation of histone acetylation Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of an acetyl group to a histone protein. GO:0035068 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035068 GO:0035069 larval midgut histolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035069 larval midgut regression The stage-specific break down of the larval midgut during Drosophila metamorphosis, to allow replacement of larval structures by tissues and structures that form the adult fly. GO:0035060 brahma complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035060 BRM complex A SWI/SNF-type complex that contains 8 to 14 proteins, including both conserved (core) and nonconserved components; contains the ATPase product of the Drosophila brm (brahma) or mammalian SMARCA2/BAF190B/BRM gene, or an ortholog thereof. GO:0035061 interchromatin granule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035061 NIF_Subcellular:sao1049471211 ICG A class of nuclear body measuring 20-25 nm in diameter and distributed throughout the interchromatin space, linked together by thin fibrils. They are believed to be storage centers for various snRNAs, snRNPs, serine/arginine-rich proteins and RNA polymerase II. A typical mammalian cell contains 25-50 clusters of interchromatin granules. Interchromatin granule clusters do not contain the heterogeneous nuclear RNA-binding proteins (hnRNPs). GO:0035062 omega speckle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035062 A nucleoplasmic speckle distributed in the interchromatin space of cells in close proximity to chromatin. Omega speckles are distinct from interchromatin granules and contain heterogeneous nuclear RNA-binding proteins (hnRNPs). GO:0035063 nuclear speck organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035063 nuclear speckle assembly|nuclear speck organisation|nuclear speckle organization|nuclear speck organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of nuclear specks, a class of nuclear body in which splicing factors are localized. GO:0035064 methylated histone binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035064 Interacting selectively and non-covalently with a histone in which a residue has been modified by methylation. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. GO:0035065 regulation of histone acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035065 Any process that modulates the frequency, rate or extent of the addition of an acetyl group to a histone protein. GO:0035066 positive regulation of histone acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035066 up regulation of histone acetylation|activation of histone acetylation|stimulation of histone acetylation|up-regulation of histone acetylation|upregulation of histone acetylation Any process that activates or increases the frequency, rate or extent of the addition of an acetyl group to a histone protein. GO:0050631 corydaline synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050631 RHEA:14773|MetaCyc:2.1.1.147-RXN|KEGG_REACTION:R07241|EC:2.1.1.147 S-adenosyl-L-methionine:protoberberine 13-C-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 2 NADPH + palmatine = S-adenosyl-L-homocysteine + corydaline + 2 NADP(+). GO:0050632 propionyl-CoA C2-trimethyltridecanoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050632 Reactome:R-HSA-193533|Reactome:R-HSA-390224|KEGG_REACTION:R05330|MetaCyc:2.3.1.154-RXN|Reactome:R-HSA-192341|EC:2.3.1.176|Reactome:R-HSA-2066781|RHEA:10408 sterol carrier protein|4,8,12-trimethyltridecanoyl-CoA:propanoyl-CoA C2-4,8,12-trimethyltridecanoyltransferase activity|propionyl-CoA C(2)-trimethyltridecanoyltransferase activity|peroxisome sterol carrier protein thiolase|sterol carrier protein X-related thiolase activity|peroxisomal 3-oxoacyl coenzyme A thiolase|SCPx|3-oxopristanoyl-CoA hydrolase activity|4,8,12-trimethyltridecanoyl-CoA:propanoyl-CoA 2-C-4,8,12-trimethyltridecanoyltransferase activity|3-oxopristanoyl-CoA thiolase activity|oxopristanoyl-CoA thiolase activity Catalysis of the reaction: 4,8,12-trimethyltridecanoyl-CoA + propanoyl-CoA = 3-oxopristanoyl-CoA + CoA. GO:0050630 (iso)eugenol O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050630 MetaCyc:2.1.1.146-RXN|EC:2.1.1.146|RHEA:17081 S-adenosyl-L-methionine:isoeugenol O-methyltransferase activity|isoeugenol O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + isoeugenol = S-adenosyl-L-homocysteine + isomethyleugenol. GO:0050635 acridone synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050635 RHEA:22224|MetaCyc:2.3.1.159-RXN|EC:2.3.1.159|KEGG_REACTION:R07250 malonyl-CoA:N-methylanthraniloyl-CoA malonyltransferase (cyclizing) Catalysis of the reaction: N-methylanthranilyl-CoA + 3 H(+) + 3 malonyl-CoA = 1,3-dihydroxy-N-methylacridone + 3 CO(2) + 4 CoA + H(2)O. OPL:0000181 parasite lifecycle stage biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OPL_0000181 A life cycle stage of a parasite. GO:0050636 vinorine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050636 KEGG_REACTION:R05876|RHEA:24016|MetaCyc:2.3.1.160-RXN|EC:2.3.1.160 acyl-CoA:16-epivellosimine O-acetyltransferase (cyclizing) Catalysis of the reaction: 16-epivellosimine + acetyl-CoA = CoA + vinorine. GO:0050633 acetyl-CoA C-myristoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050633 MetaCyc:2.3.1.155-RXN|EC:2.3.1.155|RHEA:18161 3-oxopalmitoyl-CoA-CoA acetyltransferase activity|myristoyl-CoA:acetyl-CoA C-myristoyltransferase activity|3-oxopalmitoyl-CoA hydrolase activity|myristoyl-CoA C-acetyltransferase activity Catalysis of the reaction: myristoyl-CoA + acetyl-CoA = 3-oxopalmitoyl-CoA + CoA. GO:0050634 phloroisovalerophenone synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050634 RHEA:23572|MetaCyc:2.3.1.156-RXN|EC:2.3.1.156 isovaleryl-CoA:malonyl-CoA acyltransferase activity|valerophenone synthase activity|3-methyl-1-(trihydroxyphenyl)butan-1-one synthase activity Catalysis of the reaction: isovaleryl-CoA + 3 malonyl-CoA = 4 CoASH + 3 CO2 + 3-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one. GO:0050639 10-hydroxytaxane O-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050639 RHEA:18837|MetaCyc:2.3.1.163-RXN|KEGG_REACTION:R07252|EC:2.3.1.163 acetyl coenzyme A:10-hydroxytaxane O-acetyltransferase activity|acetyl-CoA:taxan-10beta-ol O-acetyltransferase|acetyl coenzyme A: 10-hydroxytaxane O-acetyltransferase activity Catalysis of the reaction: 10-desacetyltaxuyunnanin C + acetyl-CoA = CoA + taxuyunnanin C. OPL:0000185 Trypanosoma cruzi lifecycle stage biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OPL_0000185 A lifecycle stage of Trypanosoma cruzi. GO:0050637 lovastatin nonaketide synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050637 RHEA:18565|MetaCyc:2.3.1.161-RXN|KEGG_REACTION:R07251|EC:2.3.1.161 acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing, thioester-hydrolysing) Catalysis of the reaction: S-adenosyl-L-methionine(1+) + acetyl-CoA + 18 H(+) + 8 malonyl-CoA + 11 NADPH = S-adenosyl-L-homocysteine + 8 CO(2) + 9 CoA + dihydromonacolin L + 6 H(2)O + 11 NADP(+). GO:0050638 taxadien-5-alpha-ol O-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050638 KEGG_REACTION:R06307|RHEA:22028|MetaCyc:2.3.1.162-RXN|EC:2.3.1.162 taxadien-5a-ol O-acetyltransferase activity|acetyl-CoA:taxa-4(20),11-dien-5alpha-ol O-acetyltransferase activity|acetyl coenzyme A: taxa-4(20),11(12)-dien-5alpha-ol O-acetyl transferase activity|acetyl coenzyme A:taxa-4(20),11(12)-dien-5-alpha-ol O-acetyl transferase activity|taxa-4(20),11(12)-dien-5alpha-ol-O-acetyltransferase activity|taxadien-5alpha-ol O-acetyltransferase activity|taxadienol acetyltransferase activity Catalysis of the reaction: acetyl-CoA + taxa-4(20),11-dien-5alpha-ol = CoA + taxa-4(20),11-dien-5alpha-yl acetate. OPL:0000189 Leishmania major promastigote stage biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OPL_0000189 A promastigote stage in the Leishmania major lifecycle. GO:0035056 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035056 GO:0035057 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035057 GO:0035058 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035058 GO:0035059 RCAF complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035059 replication-coupling assembly factor complex A protein complex that facilitates the assembly of nucleosomes on to newly synthesized DNA. In Drosophila, the complex comprises ASF1 and histones H3 and H4. GO:0035050 embryonic heart tube development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035050 The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field. GO:0035051 cardiocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035051 cardiac cell differentiation|heart cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual. GO:0035052 dorsal vessel aortic cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035052 The commitment of dorsal vessel cardioblast cells to an aortic cell fate and their capacity to differentiate into aortic cells. An example of this process is found in Drosophila melanogaster. GO:0035053 dorsal vessel heart proper cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035053 The commitment of dorsal vessel cardioblast cells to a heart proper cell fate and their capacity to differentiate into heart cells. An example of this process is found in Drosophila melanogaster. GO:0035054 embryonic heart tube anterior/posterior pattern specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035054 The establishment, maintenance and elaboration of cell differentiation that results in the anterior/posterior subdivision of the embryonic heart tube. In Drosophila this results in subdivision of the dorsal vessel into to the posterior heart proper and the anterior aorta. GO:0035055 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035055 GO:0050642 2-alpha-hydroxytaxane 2-O-benzoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050642 EC:2.3.1.166|KEGG_REACTION:R06310|MetaCyc:2.3.1.166-RXN|RHEA:18741 2a-hydroxytaxane 2-O-benzoyltransferase activity|2-debenzoyl-7,13-diacetylbaccatin III-2-O-benzoyl transferase activity|benzoyl-CoA:taxane 2alpha-O-benzoyltransferase activity|benzoyl-CoA:taxan-2alpha-ol O-benzoyltransferase activity|2alpha-hydroxytaxane 2-O-benzoyltransferase activity|benzoyl-CoA:taxane 2-alpha-O-benzoyltransferase activity Catalysis of the reaction: 10-deacetyl-2-debenzoylbaccatin III + benzoyl-CoA = 10-deacetylbaccatin III + CoA. GO:0050643 10-deacetylbaccatin III 10-O-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050643 RHEA:20137|KEGG_REACTION:R06311|MetaCyc:2.3.1.167-RXN|EC:2.3.1.167 acetyl-CoA:taxan-10beta-ol O-acetyltransferase Catalysis of the reaction: 10-deacetylbaccatin III + acetyl-CoA = baccatin III + CoA. GO:0050640 isopenicillin-N N-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050640 EC:2.3.1.164|RHEA:20720|MetaCyc:2.3.1.164-RXN isopenicillin N:acyl-CoA acyltransferase activity|acyl-coenzyme A:6-aminopenicillanic-acid-acyltransferase activity|isopenicillin-N acyltransferase activity|acyl-CoA:isopenicillin N N-acyltransferase activity|acyl-coenzyme A:isopenicillin N acyltransferase activity Catalysis of the reaction: phenylacetyl-CoA + isopenicillin N + H2O = CoA + penicillin G + L-2-aminohexanedioate. GO:0050641 6-methylsalicylic acid synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050641 EC:2.3.1.165|MetaCyc:2.3.1.165-RXN|RHEA:12240|KEGG_REACTION:R07253 acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl-reducing, thioester-hydrolysing and cyclizing)|6-MSAS activity|MSAS activity Catalysis of the reaction: acetyl-CoA + 3 H(+) + 3 malonyl-CoA + NADPH = 6-methylsalicylate + 3 CO(2) + 4 CoA + H(2)O + NADP(+). GO:0050646 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050646 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid binding Interacting selectively and non-covalently with 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid, a straight-chain fatty acid with twenty carbon atoms and four double bonds. GO:0050647 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050647 5-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid binding Interacting selectively and non-covalently with 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid, a straight-chain fatty acid with twenty carbon atoms and four double bonds. GO:0050644 cis-p-coumarate glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050644 MetaCyc:2.4.1.209-RXN|RHEA:13129|EC:2.4.1.209|KEGG_REACTION:R05324 UDP-glucose:cis-p-coumarate beta-D-glucosyltransferase activity Catalysis of the reaction: cis-4-coumarate + UDP-D-glucose = 4'-O-beta-D-glucosyl-cis-4-coumarate + H(+) + UDP. GO:0050645 limonoid glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050645 EC:2.4.1.210|RHEA:11256|MetaCyc:2.4.1.210-RXN LGTase activity|limonoid UDP-glucosyltransferase activity|uridine diphosphoglucose-limonoid glucosyltransferase activity Catalysis of the reaction: UDP-glucose + limonin = glucosyl-limonin + UDP. OPL:0000175 Trypanosoma brucei trypomastigote stage biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OPL_0000175 A trypomastigote stage in the Trypanosoma brucei lifecycle that occurs in the vertebrate host. GO:0050648 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050648 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid binding Interacting selectively and non-covalently with 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid, a straight-chain fatty acid with twenty carbon atoms and four double bonds. GO:0050649 testosterone 6-beta-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050649 testosterone 6b-hydroxylase activity Catalysis of the reaction: testosterone + donor-H2 + O2 = 6-beta-hydroxytestosterone + H2O. OPL:0000177 Schistosoma haematobium lifecycle stage biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OPL_0000177 A lifecycle stage of Schistosoma haematobium. GO:0035045 sperm plasma membrane disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035045 sperm plasma membrane catabolism|sperm plasma membrane degradation|sperm plasma membrane breakdown The gradual disintegration of the sperm plasma membrane following insemination. This process is seen in Drosophila after entry of the entire sperm, surrounded by its plasma membrane, into the egg. CHEBI:13601 3-oxo-5alpha-steroid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_13601 GO:0035046 pronuclear migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035046 The directed movement of the male and female pronuclei towards each other prior to their fusion. GO:0035047 centrosomal and pronuclear rotation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035047 The rotation of centrosomes and associated pronuclei in one-cell embryos such as those of Caenorhabditis elegans, occurring as a transition between pronuclear migration and pronuclear fusion. GO:0035048 obsolete splicing factor protein import into nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035048 splicing factor protein transport from cytoplasm to nucleus|splicing factor protein-nucleus import OBSOLETE. The directed movement of a pre-mRNA splicing factor from the cytoplasm into the nucleus, across the nuclear membrane. GO:0035049 juvenile hormone acid methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035049 Catalysis of the transfer of a methyl group to juvenile hormone acid. GO:0035040 sperm nuclear envelope removal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035040 Removal of the sperm nuclear envelope, allowing entry of maternal factors into the sperm nucleus. GO:0035041 sperm chromatin decondensation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035041 Unwinding of the condensed nuclear chromatin of an inactive sperm nucleus. GO:0035042 fertilization, exchange of chromosomal proteins biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035042 sperm-specific histone replacement|sperm-specific histone exchange Replacement of sperm-specific chromosomal proteins with somatic histones, to allow the paternal genome to acquire a nucleosomal chromatin organization compatible with nuclear activity. GO:0035043 male pronuclear envelope synthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035043 Assembly of a nuclear envelope containing nuclear pores and a lamina around the male pronucleus, the final step in sperm pronuclear formation. GO:0035044 sperm aster formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035044 Formation and organization of an aster composed of microtubule arrays originating from the sperm basal body and extending virtually to the egg periphery. The sperm aster ensures the appropriate positioning of the male and female pronuclei. GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050653 chondroitin sulfate proteoglycan formation, polysaccharide chain formation|chondroitin sulphate proteoglycan biosynthesis, polysaccharide chain biosynthesis|chondroitin sulphate proteoglycan biosynthesis, polysaccharide chain biosynthetic process|chondroitin sulfate proteoglycan chain elongation|chondroitin sulfate proteoglycan anabolism, polysaccharide chain anabolism|chondroitin sulfate proteoglycan synthesis, polysaccharide chain synthesis|chondroitin sulfate proteoglycan formation, polysaccharide chain biosynthesis The elongation of chondroitin sulfate proteoglycan chains by alternate addition of N-acetylhexosamine and GlcUA residues to the GAG-protein linkage region tetrasaccharide of chondroitin sulfate. GO:0050654 chondroitin sulfate proteoglycan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050654 chondroitin sulphate proteoglycan metabolic process|chondroitin sulfate proteoglycan metabolism|chondroitin sulphate proteoglycan metabolism The chemical reactions and pathways involving chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. GO:0050651 dermatan sulfate proteoglycan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050651 dermatan sulfate proteoglycan synthesis|dermatan sulfate proteoglycan formation|chondroitin sulfate B proteoglycan biosynthesis|chondroitin sulfate B proteoglycan biosynthetic process|dermatan sulphate proteoglycan biosynthesis|dermatan sulphate proteoglycan biosynthetic process|dermatan sulfate proteoglycan anabolism|dermatan sulfate proteoglycan biosynthesis The chemical reactions and pathways resulting in the formation of dermatan sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are dermatan sulfate (chondroitin sulfate B). Dermatan sulfate is a glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units. GO:1902409 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902409 GO:0050652 dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050652 chondroitin sulfate B proteoglycan chain elongation|dermatan sulfate proteoglycan anabolism, polysaccharide chain anabolism|chondroitin sulfate B proteoglycan biosynthesis, polysaccharide chain biosynthetic process|chondroitin sulfate B proteoglycan biosynthesis, polysaccharide chain biosynthesis|dermatan sulfate proteoglycan synthesis, polysaccharide chain synthesis|dermatan sulfate proteoglycan formation, polysaccharide chain biosynthesis|dermatan sulfate proteoglycan formation, polysaccharide chain formation|dermatan sulphate proteoglycan biosynthesis, polysaccharide chain biosynthetic process|dermatan sulphate proteoglycan biosynthesis, polysaccharide chain biosynthesis|dermatan sulfate proteoglycan chain elongation The elongation of dermatan sulfate proteoglycan chains by alternate addition of N-acetylhexosamine and GlcUA residues to the GAG-protein linkage region tetrasaccharide of dermatan sulfate. GO:0050657 nucleic acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050657 The directed movement of nucleic acids, single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:1902407 assembly of actomyosin apparatus involved in mitotic cytokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902407 cytokinesis, formation of actomyosin apparatus involved in mitotic cell cycle|actomyosin apparatus assembly involved in cytokinesis involved in mitotic cell cycle|formation of actomyosin apparatus involved in cytokinesis involved in mitotic cell cycle Any assembly of mitotic cytokinetic actomyosin apparatus. GO:0050658 RNA transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050658 The directed movement of RNA, ribonucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:1902408 mitotic cytokinesis, site selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902408 site selection involved in cell cycle cytokinesis involved in mitotic cell cycle|site selection involved in cytokinesis involved in mitotic cell cycle Any cytokinesis, site selection that is involved in mitotic cell cycle. GO:0050655 dermatan sulfate proteoglycan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050655 dermatan sulphate proteoglycan metabolism|dermatan sulfate proteoglycan metabolism|chondroitin sulfate B proteoglycan metabolic process|chondroitin sulfate B proteoglycan metabolism|dermatan sulphate proteoglycan metabolic process The chemical reactions and pathways involving dermatan sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are dermatan sulfate (chondroitin sulfate B). Dermatan sulfate is a glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units. GO:1902405 mitotic actomyosin contractile ring localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902405 contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle Any actomyosin contractile ring localization that is involved in mitotic cell cycle. GO:1902406 mitotic actomyosin contractile ring maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902406 cytokinesis, contractile ring maintenance, involved in cytokinesis during cell cycle involved in mitotic cell cycle|contractile ring maintenance involved in cell cycle cytokinesis involved in mitotic cell cycle Any actomyosin contractile ring maintenance that is involved in mitotic cell cycle. GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050656 adenosine 3'-phosphate 5'-phosphosulfate binding|phosphoadenosine phosphosulfate binding|3'-phosphoadenosine 5'-phosphosulphate binding|3'-phosphoadenylyl-sulfate binding|PAPS binding Interacting selectively and non-covalently with 3'-phosphoadenosine 5'-phosphosulfate (PAPS), a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems. GO:1902403 signal transduction involved in mitotic DNA integrity checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902403 intracellular signal transduction involved in topo II checkpoint|signal transduction via intracellular signaling cascade involved in topo II checkpoint|signal transmission via intracellular cascade involved in topo II checkpoint|intracellular signaling chain involved in topo II checkpoint|intracellular signal transduction pathway involved in topo II checkpoint|intracellular signaling cascade involved in topoisomerase II checkpoint|intracellular signaling pathway involved in mitotic cell cycle G2/M transition decatenation checkpoint|signal transduction via intracellular signaling cascade involved in topoisomerase II checkpoint|intracellular signaling pathway involved in mitotic DNA integrity checkpoint|intracellular signaling cascade involved in mitotic cell cycle G2/M transition decatenation checkpoint|intracellular signaling cascade involved in mitotic DNA integrity checkpoint|intracellular signal transduction pathway involved in topoisomerase II checkpoint|signal transmission via intracellular cascade involved in topoisomerase II checkpoint|intracellular signaling pathway involved in topo II checkpoint|intracellular signal transduction involved in mitotic cell cycle G2/M transition decatenation checkpoint|intracellular signaling pathway involved in topoisomerase II checkpoint|signal transduction via intracellular signaling cascade involved in mitotic cell cycle G2/M transition decatenation checkpoint|signal transduction via intracellular signaling cascade involved in mitotic DNA integrity checkpoint|signal transmission via intracellular cascade involved in mitotic cell cycle G2/M transition decatenation checkpoint|signal transmission via intracellular cascade involved in mitotic DNA integrity checkpoint|intracellular signaling cascade involved in topo II checkpoint|intracellular signal transduction pathway involved in mitotic cell cycle G2/M transition decatenation checkpoint|intracellular signaling chain involved in topoisomerase II checkpoint|intracellular signaling chain involved in mitotic cell cycle G2/M transition decatenation checkpoint|intracellular signal transduction pathway involved in mitotic DNA integrity checkpoint|intracellular signaling chain involved in mitotic DNA integrity checkpoint|intracellular signal transduction involved in topoisomerase II checkpoint Any intracellular signal transduction that is involved in mitotic DNA integrity checkpoint. GO:1902404 mitotic actomyosin contractile ring contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902404 contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|cytokinesis, actomyosin ring contraction involved in mitotic cell cycle Any actomyosin contractile ring contraction that is involved in mitotic cell cycle. GO:1902401 detection of stimulus involved in mitotic DNA damage checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902401 stimulus sensing involved in mitotic DNA damage checkpoint|stimulus detection involved in mitotic DNA damage checkpoint|perception of stimulus involved in mitotic DNA damage checkpoint Any detection of stimulus that is involved in mitotic DNA damage checkpoint. GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050659 EC:2.8.2.33|KEGG_REACTION:R07288|KEGG_REACTION:R02181|Reactome:R-HSA-2018659|MetaCyc:RXN-7954|MetaCyc:RXN-7953 GalNAc4S-6ST|3'-phosphoadenylyl-sulfate:dermatan 6'-sulfotransferase activity|N-acetylgalactosamine 4-sulfate 6-O-sulphotransferase activity Catalysis of the reactions: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan 6'-sulfate and 3'-phosphoadenylyl sulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate. GO:1902402 signal transduction involved in mitotic DNA damage checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902402 intracellular signaling cascade involved in mitotic DNA damage checkpoint|signal transduction via intracellular signaling cascade involved in mitotic DNA damage checkpoint|intracellular signal transduction pathway involved in mitotic DNA damage checkpoint|signal transmission via intracellular cascade involved in mitotic DNA damage checkpoint|intracellular signaling pathway involved in mitotic DNA damage checkpoint|intracellular signaling chain involved in mitotic DNA damage checkpoint Any intracellular signal transduction that is involved in mitotic DNA damage checkpoint. GO:1902400 intracellular signal transduction involved in G1 DNA damage checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902400 intracellular signaling cascade involved in G1 DNA damage checkpoint|intracellular signal transduction involved in G1/S DNA damage checkpoint|signal transduction via intracellular signaling cascade involved in G1/S DNA damage checkpoint|signal transmission via intracellular cascade involved in G1/S DNA damage checkpoint|intracellular signal transduction pathway involved in G1/S DNA damage checkpoint|intracellular signaling chain involved in G1/S DNA damage checkpoint|signal transduction via intracellular signaling cascade involved in G1 DNA damage checkpoint|signal transmission via intracellular cascade involved in G1 DNA damage checkpoint|intracellular signal transduction pathway involved in G1 DNA damage checkpoint|intracellular signaling chain involved in G1 DNA damage checkpoint|intracellular signaling pathway involved in G1/S DNA damage checkpoint|intracellular signaling pathway involved in G1 DNA damage checkpoint|intracellular signaling cascade involved in G1/S DNA damage checkpoint Any intracellular signal transduction that is involved in G1 DNA damage checkpoint. OPL:0000165 Plasmodium falciparum lifecycle stage biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OPL_0000165 A lifecycle stage of Plasmodium falciparum. OBA:VT1000777 urinary system trait biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_VT1000777 The quality when measured in renal system. GO:0035034 histone acetyltransferase regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035034 histone acetylase regulator activity Modulates the activity of histone acetyltransferase. GO:0035035 histone acetyltransferase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035035 histone acetylase binding Interacting selectively and non-covalently with the enzyme histone acetyltransferase. GO:0035036 sperm-egg recognition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035036 The initial contact step made between the sperm plasma membrane and outer layer of the egg during fertilization. OPL:0000169 Trypanosoma cruzi trypomastigote stage biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OPL_0000169 A trypomastigote stage in the Trypanosoma cruzi lifecycle that occurs either in the vertebrate host or an insect vector. GO:0035037 sperm entry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035037 An endocytosis process that results in penetration of the egg shell through the micropyle (a specialized anterior opening in the vitelline envelope) and entry of the entire sperm, including the surrounding plasma membrane and the sperm tail, into the egg cytoplasm. This step in fertilization is seen in Drosophila, where a plasma membrane fusion event between the sperm and the egg does not occur. GO:0035038 female pronucleus assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035038 female pronucleus assembly Assembly of the haploid nucleus of the unfertilized egg. GO:0035039 male pronucleus assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035039 male pronucleus formation The conversion at fertilization of the inactive sperm nucleus into a male pronucleus with its chromosomes processed for the first zygotic division. GO:0035030 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035030 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050650 chondroitin sulphate proteoglycan biosynthetic process|chondroitin sulfate proteoglycan anabolism|chondroitin sulfate proteoglycan biosynthesis|chondroitin sulphate proteoglycan biosynthesis|chondroitin sulfate proteoglycan synthesis|chondroitin sulfate proteoglycan formation The chemical reactions and pathways resulting in the formation of chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. GO:0035031 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035031 GO:0035032 phosphatidylinositol 3-kinase complex, class III biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035032 class III PI3K complex|phosphoinositide 3-kinase complex, class III A phosphatidylinositol 3-kinase complex that contains a catalytic class III phosphoinositide 3-kinase (PI3K) subunit bound to a regulatory (adaptor) subunit. Additional adaptor proteins may be present. Class III PI3Ks have a substrate specificity restricted to phosphatidylinositol (PI). GO:0035033 histone deacetylase regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035033 Modulates the activity of histone deacetylase. GO:0001810 regulation of type I hypersensitivity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001810 Any process that modulates the frequency, rate, or extent of type I hypersensitivity, a type of inflammatory response. OPL:0000310 Vertebrate blood biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OPL_0000310 Blood that is part of or originated from a vertebrate. CHEBI:37556 O-(alpha-D-mannosyl)-L-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37556 CHEBI:62523 (-)-trans-permethrin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62523 CHEBI:37557 O-(alpha-D-mannosyl)-L-threonine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37557 CHEBI:62521 trans-permethrin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62521 CHEBI:37554 fatty acyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37554 OPL:0000313 Mammalia cerebrospinal fluid biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OPL_0000313 Cerebrospinal fluid that is a part of or originated from a mammal. CHEBI:37555 omega-carboxyacyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37555 GO:0001819 positive regulation of cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001819 upregulation of cytokine production|positive regulation of cytokine secretion|up regulation of cytokine production|activation of cytokine production|stimulation of cytokine production|positive regulation of cytokine biosynthetic process|up-regulation of cytokine production Any process that activates or increases the frequency, rate or extent of production of a cytokine. CHEBI:62527 (3-phenoxyphenyl)methanol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62527 CHEBI:62528 (1S,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62528 CHEBI:37558 aryl dialkyl phosphate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37558 CHEBI:62526 (2S,3S,5R,10R,12S,14S,15R,16R)-2-amino-12,16-dimethylicosane-3,5,10,14,15-pentol(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62526 GO:0001815 positive regulation of antibody-dependent cellular cytotoxicity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001815 upregulation of antibody-dependent cellular cytotoxicity|stimulation of antibody-dependent cellular cytotoxicity|positive regulation of antibody dependent cell death|up-regulation of antibody-dependent cellular cytotoxicity|activation of antibody-dependent cellular cytotoxicity|positive regulation of antibody-dependent cell killing|up regulation of antibody-dependent cellular cytotoxicity|positive regulation of antibody dependent cell killing|positive regulation of antibody-dependent cell death Any process that activates or increases the frequency, rate or extent of antibody-dependent cellular cytotoxicity. GO:0001816 cytokine production biolink:BiologicalProcess go-plus gocheck_do_not_annotate|goslim_pir http://purl.obolibrary.org/obo/GO_0001816 cytokine secretion|interferon secretion|interleukin production|interferon production|interleukin secretion|cytokine metabolic process|cytokine biosynthetic process The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0001817 regulation of cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001817 regulation of cytokine biosynthetic process|regulation of cytokine secretion|regulation of cytokine biosynthesis|regulation of cytokine anabolism|regulation of cytokine synthesis|regulation of cytokine formation Any process that modulates the frequency, rate, or extent of production of a cytokine. GO:0001818 negative regulation of cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001818 down regulation of cytokine production|negative regulation of cytokine secretion|inhibition of cytokine biosynthetic process|downregulation of cytokine production|negative regulation of cytokine anabolism|negative regulation of cytokine synthesis|down-regulation of cytokine production|down regulation of cytokine biosynthetic process|negative regulation of cytokine formation|downregulation of cytokine biosynthetic process|inhibition of cytokine production|negative regulation of cytokine biosynthetic process|negative regulation of cytokine biosynthesis|down-regulation of cytokine biosynthetic process Any process that stops, prevents, or reduces the rate of production of a cytokine. GO:0001811 negative regulation of type I hypersensitivity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001811 down regulation of type I hypersensitivity|downregulation of type I hypersensitivity|down-regulation of type I hypersensitivity|inhibition of type I hypersensitivity Any process that stops, prevents, or reduces the rate of type I hypersensitivity, a type of inflammatory response. GO:0001812 positive regulation of type I hypersensitivity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001812 upregulation of type I hypersensitivity|up regulation of type I hypersensitivity|activation of type I hypersensitivity|stimulation of type I hypersensitivity|up-regulation of type I hypersensitivity Any process that activates or increases the frequency, rate or extent of type I hypersensitivity, a type of inflammatory response. GO:0001813 regulation of antibody-dependent cellular cytotoxicity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001813 regulation of antibody dependent cell death|regulation of antibody-dependent cell killing|regulation of antibody dependent cell killing|regulation of antibody-dependent cell death Any process that modulates the frequency, rate, or extent of antibody-dependent cellular cytotoxicity. CHEBI:37550 sphingosine 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37550 GO:0001814 negative regulation of antibody-dependent cellular cytotoxicity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001814 negative regulation of antibody-dependent cell death|negative regulation of antibody dependent cell death|negative regulation of antibody-dependent cell killing|down-regulation of antibody-dependent cellular cytotoxicity|downregulation of antibody-dependent cellular cytotoxicity|down regulation of antibody-dependent cellular cytotoxicity|negative regulation of antibody dependent cell killing|inhibition of antibody-dependent cellular cytotoxicity Any process that stops, prevents, or reduces the rate of antibody-dependent cellular cytotoxicity. GO:0001820 serotonin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001820 5-hydroxytryptamine secretion|5-HT secretion|serotonin release The regulated release of serotonin by a cell. Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine synthesised in serotonergic neurons in the central nervous system, enterochromaffin cells in the gastrointestinal tract and some immune system cells. GO:0001821 histamine secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001821 The regulated release of histamine by a cell or tissue. It is formed by decarboxylation of histidine and it acts through receptors in smooth muscle and in secretory systems. CHEBI:62531 (1S,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62531 CHEBI:37568 dTTP(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37568 CHEBI:37565 GTP(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37565 CHEBI:62533 oligogalacturonide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62533 CHEBI:37569 (+)-abscisate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37569 CHEBI:62537 N-acylphosphatidylethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62537 GO:0001826 inner cell mass cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001826 The process in which a relatively unspecialized cell acquires specialized features of an inner cell mass cell. GO:0001827 inner cell mass cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001827 The cell fate commitment of precursor cells that will become inner cell mass cells. GO:0001828 inner cell mass cellular morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001828 The morphogenesis of cells in the inner cell mass. GO:0001829 trophectodermal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001829 trophectoderm cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a trophectoderm cell. GO:0001822 kidney development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001822 Wikipedia:Kidney_development nephrogenesis The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine. CHEBI:37563 CTP(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37563 GO:0001823 mesonephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001823 Wolffian body development The process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. In mammals, the mesonephros is the second of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the mesonephros will form the mature kidney. GO:0001824 blastocyst development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001824 The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm. GO:0001825 blastocyst formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001825 The initial formation of a blastocyst from a solid ball of cells known as a morula. CHEBI:62545 acyl alpha,alpha-trehalose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62545 CHEBI:37534 ribitol 5-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37534 CHEBI:62546 monoacyl alpha,alpha-trehalose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62546 CHEBI:37532 phorbol ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37532 CHEBI:62543 3-oxotetradecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62543 CHEBI:37533 azo compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37533 CHEBI:62549 acyl alpha,alpha-trehalose derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62549 CHEBI:62547 polyacyl alpha,alpha-trehalose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62547 CHEBI:62548 3-oxodecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62548 CHEBI:37537 phorbol 13-acetate 12-myristate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37537 CHEBI:37530 phosphatidylinositol 4-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37530 CHEBI:37531 polyprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37531 CHEBI:62552 polyacyl alpha,alpha-trehalose derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62552 CHEBI:86500 N-myristoylglycinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86500 CHEBI:37545 altrarate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37545 CHEBI:37546 D-altrarate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37546 CHEBI:62554 fumonisin B1(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62554 CHEBI:62555 3-hydroxyisovaleryl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62555 GO:0001808 negative regulation of type IV hypersensitivity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001808 downregulation of type IV hypersensitivity|down regulation of type IV hypersensitivity|inhibition of type IV hypersensitivity|down-regulation of type IV hypersensitivity Any process that stops, prevents, or reduces the rate of type IV hypersensitivity, a type of inflammatory response. CHEBI:37549 glycoside phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37549 GO:0001809 positive regulation of type IV hypersensitivity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001809 upregulation of type IV hypersensitivity|stimulation of type IV hypersensitivity|activation of type IV hypersensitivity|up-regulation of type IV hypersensitivity|up regulation of type IV hypersensitivity Any process that activates or increases the frequency, rate or extent of type IV hypersensitivity, a type of inflammatory response. CHEBI:86506 (9Z,12Z)-octadeca-9,12-dien-6-ynoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86506 CHEBI:62558 (S)-3-hydroxylauroyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62558 CHEBI:37547 L-altrarate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37547 CHEBI:86508 alpha-aminobutyrate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86508 GO:0001804 negative regulation of type III hypersensitivity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001804 down-regulation of type III hypersensitivity|inhibition of type III hypersensitivity|down regulation of type III hypersensitivity|downregulation of type III hypersensitivity Any process that stops, prevents, or reduces the rate of type III hypersensitivity, a type of inflammatory response. GO:0001805 positive regulation of type III hypersensitivity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001805 stimulation of type III hypersensitivity|up-regulation of type III hypersensitivity|upregulation of type III hypersensitivity|up regulation of type III hypersensitivity|activation of type III hypersensitivity Any process that activates or increases the frequency, rate or extent of type III hypersensitivity, a type of inflammatory response. GO:0001806 type IV hypersensitivity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001806 Wikipedia:Type_IV_hypersensitivity delayed hypersensitivity response|delayed-type hypersensitivity An inflammatory response driven by T cell recognition of processed soluble or cell-associated antigens leading to cytokine release and leukocyte activation. GO:0001807 regulation of type IV hypersensitivity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001807 Any process that modulates the frequency, rate, or extent of type IV hypersensitivity, a type of inflammatory response. GO:0001800 negative regulation of type IIb hypersensitivity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001800 inhibition of type IIb hypersensitivity|down regulation of type IIb hypersensitivity|downregulation of type IIb hypersensitivity|down-regulation of type IIb hypersensitivity Any process that stops, prevents, or reduces the rate of type IIb hypersensitivity, a type of inflammatory response. GO:0001801 positive regulation of type IIb hypersensitivity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001801 up-regulation of type IIb hypersensitivity|upregulation of type IIb hypersensitivity|up regulation of type IIb hypersensitivity|activation of type IIb hypersensitivity|stimulation of type IIb hypersensitivity Any process that activates or increases the frequency, rate or extent of type IIb hypersensitivity, a type of inflammatory response. GO:0001802 type III hypersensitivity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001802 Wikipedia:Type_III_hypersensitivity An inflammatory response resulting from recognition of immune complexes via complement or Fc receptors on effector cells leading to activation of neutrophils and other leukocytes and damage to bystander tissue. GO:0001803 regulation of type III hypersensitivity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001803 Any process that modulates the frequency, rate, or extent of type III hypersensitivity, a type of inflammatory response. GO:1990950 metaphase/anaphase transition of meiosis II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990950 meiosis II metaphase/anaphase transition|second meiotic metaphase/anaphase transition The cell cycle process in which a cell progresses from metaphase to anaphase as part of meiosis II. GO:1990951 obsolete manchette assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990951 OBSOLETE. The assembly and organization of the manchette, a tubular array of microtubules, possibly also containing actin filaments, that extends from the perinuclear ring surrounding the spermatid nucleus to the flagellar axoneme. CHEBI:37519 cyclohepta-1,3,5-triene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37519 CHEBI:62563 cellooligosaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62563 CHEBI:37512 organic thiophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37512 CHEBI:37511 thiophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37511 CHEBI:62566 CDP-1L-myo-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62566 CHEBI:37515 D-fructofuranose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37515 GO:1990956 fibroblast chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990956 The directed movement of a fibroblast guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). GO:1990957 NPHP complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990957 NPHP module A protein complex that is located at the ciliary transition zone and consists of the NPHP4 and NPHP1 proteins. It acts as an organiser of the transition zone inner structure, specifically the Y-shaped links, in conjunction with the MKS complex. It is involved in ciliary protein trafficking and is required for correct functioning of the WNT and Hippo signaling pathways. GO:1990958 obsolete response to thyrotropin-releasing hormone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990958 response to TRH OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyrotropin-releasing hormone (TRH) stimulus. TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary. GO:1990959 eosinophil homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990959 eosinocyte homeostasis|eosinophilic leucocyte homeostasis|eosinophilic leukocyte homeostasis|eosinophilic granulocyte homeostasis The process of regulating the proliferation and elimination of eosinophils such that the total number of eosinophils within a whole or part of an organism is stable over time in the absence of an outside stimulus. GO:1990952 obsolete manchette disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990952 manchette clearance OBSOLETE. A cellular process that results in the breakdown of a manchette. GO:1990953 intramanchette transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990953 IMT The movement of vesicles and protein complexes carried out by molecular motors, kinesins and dynein, along the microtubule tracks within the manchette and by myosin along actin filaments. GO:1990954 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990954 GO:1990955 G-rich single-stranded DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990955 Interacting selectively and non-covalently with G-rich, single-stranded DNA. GO:1990960 basophil homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990960 basophilic leucocyte homeostasis The process of regulating the proliferation and elimination of basophils such that the total number of basophils within a whole or part of an organism is stable over time in the absence of an outside stimulus. PO:0000431 megasporocyte biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000431 Poaceae megasporocyte (narrow)|大胞子母細胞 (Japanese, exact)|MMC (exact)|Zea megasporocyte (narrow)|megasporocito (Spanish, exact)|megaspore mother cell (exact) A sporocyte (PO:0006204) that produces four haploid (1n) megaspores (PO:0020019). GO:1990961 xenobiotic detoxification by transmembrane export across the plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990961 drug transmembrane export A process that reduces or removes the toxicity of a xenobiotic by exporting it outside the cell. GO:1990962 xenobiotic transport across blood-brain barrier biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990962 drug transport across blood-brain barrier The directed movement of a xenobiotic through the blood-brain barrier. CHEBI:62571 beta-D-Galp-(1->3)-beta-D-GalpNAc-(1->3)-alpha-D-Galp-(1->4)-beta-D-Galp-(1->4)-beta-D-Glcp-(1<->1')-Cer biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62571 CHEBI:62574 bis(1L-myo-inositol) 3,1'-phosphate 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62574 CHEBI:86520 (2R)-2-methyltetradecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86520 CHEBI:86521 (2S)-2-methyltetradecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86521 CHEBI:62573 CDP-1L-myo-inositol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62573 CHEBI:13534 acyl-carrier protein biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_13534 CHEBI:62576 bis(1L-myo-inositol) 3,1'-phosphate 1-phosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62576 CHEBI:37527 acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37527 CHEBI:37528 sn-glycerol 1-phosphates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37528 CHEBI:37525 O-phospho-L-threonine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37525 CHEBI:37526 tigliane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37526 GO:1990967 obsolete multi-organism toxin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990967 typhoid toxin transport OBSOLETE. The directed movement of a toxin into, out of or within a cell, or between cells where two or more organisms of the same or different species are involved. GO:1990968 modulation by host of RNA binding by virus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990968 modulation by host of viral protein:RNA interaction A process in which a host organism modulates the frequency, rate or extent of a viral gene product binding to RNA. GO:1990969 modulation by host of viral RNA-binding transcription factor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990969 modulation by host of viral Tat activity A process in which a host organism modulates the frequency, rate or extent of the activity of a viral RNA-binding transcription factor. GO:1990963 establishment of blood-retinal barrier biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990963 establishment of BRB|establishment of blood-retina barrier Establishment of the barrier between the blood and the retina. The blood-retinal barrier is located at two levels, forming an outer barrier in the retinal pigment epithelium and an inner barrier in the endothelial membrane of the retinal vessels. Both these membranes have tight junctions of the 'nonleaky' type. GO:1990964 actin cytoskeleton-regulatory complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990964 IntAct:EBI-11710254 A protein complex probably required for the internalization of endosomes during actin-coupled endocytosis. Links the site of endocytosis to the cell membrane-associated actin cytoskeleton, coordinating ARP2/3 stimulation at the later stages of endocytosis. Present in the late endocytic coat. GO:1990965 cytosylglucuronate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990965 Catalysis of the reaction: cytosylglucuronic acid + H(+) = cytosylarabinopyranose + CO(2). GO:1990966 ATP generation from poly-ADP-D-ribose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990966 The process of generating ATP in the nucleus from poly-ADP-D-ribose. Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming. GO:1990970 trans-activation response element binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990970 TAR binding Interacting selectively and non-covalently with a trans-activation response (TAR) element, a hairpin RNA structure located at the 5' end of all HIV-1 transcripts, and which is required for trans-activation of a viral promoter. GO:1990971 EMILIN complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990971 IntAct:EBI-11740139|IntAct:EBI-11740215|IntAct:EBI-11740275|IntAct:EBI-11705777 Elastic microfibrillar interface 2 complex|Elastic microfibrillar interface 1 complex|EMILIN-2 complex|EMILIN-1 complex Glycoprotein complex of the C1q/TNF superfamily found in the extracellular matrix (ECM) where it is an important component of the elastic fiber system. A homotrimer that will combine to form supramolecular EMILIN structures. GO:1990972 multimerin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990972 IntAct:EBI-11783711 Multimerin-2 complex|Multimerin-1 complex|p155 complex|Elastic microfibrillar interface 4 complex|Elastic microfibrillar interface 3 complex|EMILIN-4 complex|EMILIN-3 complex|Platelet glycoprotein Ia* complex Glycoprotein complex of the C1q/TNF superfamily involved in cell adhesion. A homotrimer that will combine to form supramolecular Multimerin structures. GO:1990973 transmembrane actin-associated (TAN) line biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990973 TAN line A linear array of nuclear envelope membrane proteins composed of nesprin-2G and SUN2, which couple the nucleus to moving actin cables, resulting in rearward nuclear transport (away from the leading edge). GO:0050800 obsolete hydrolase activity, acting on acid anhydrides, acting on GTP, involved in cellular and subcellular movement biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050800 hydrolase activity, acting on acid anhydrides, acting on GTP, involved in cellular and subcellular movement OBSOLETE. Catalysis of the hydrolysis of GTP to directly drive the cellular or subcellular transport of a substance. GO:0050801 ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050801 electrolyte homeostasis|negative regulation of crystal formation|regulation of ion homeostasis Any process involved in the maintenance of an internal steady state of ions within an organism or cell. PO:0000423 plant zygote biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000423 cigoto (Spanish, exact)|zygote (broad)|植物接合子、接合体 (Japanese, exact) A native plant cell (PO:0025606) which is a whole plant (PO:0000003) in the plant zygote stage (PO:0001097). GO:0050804 modulation of chemical synaptic transmission biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0050804 regulation of chemical synaptic transmission|modulation of synaptic transmission|regulation of synaptic transmission Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission. GO:0050805 negative regulation of synaptic transmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050805 down-regulation of synaptic transmission|inhibition of synaptic transmission|down regulation of synaptic transmission|downregulation of synaptic transmission Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. GO:0050802 circadian sleep/wake cycle, sleep biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050802 The part of the circadian sleep/wake cycle where the organism is asleep. GO:0050803 regulation of synapse structure or activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050803 Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell). GO:0050808 synapse organization biolink:BiologicalProcess go-plus goslim_synapse|goslim_drosophila http://purl.obolibrary.org/obo/GO_0050808 synapse morphogenesis|synapse organisation|synapse development|synapse organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell). GO:0050809 diazepam binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050809 diazepam binding inhibitor activity|Valium binding Interacting selectively and non-covalently with diazepam, one of the most widely used benzodiazepine drugs. It is used as an anti-anxiety-hypnotic agent and has the proprietary name Valium. GO:0050806 positive regulation of synaptic transmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050806 up regulation of synaptic transmission|activation of synaptic transmission|stimulation of synaptic transmission|up-regulation of synaptic transmission|upregulation of synaptic transmission Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. GO:0050807 regulation of synapse organization biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0050807 regulation of synapse structure|regulation of synapse organization and biogenesis|regulation of synapse organisation Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell). GO:1990978 obsolete response to viscosity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990978 OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a viscosity stimulus. GO:1990979 obsolete copper ion transport across blood-brain barrier biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990979 copper ion transport across BBB OBSOLETE. The directed movement of copper ions passing through the blood-brain barrier. GO:1990974 actin-dependent nuclear migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990974 actin-dependent nuclear movement The process whereby the centrosome is held at the cell center while the nucleus moves to the cell rear by actin retrograde flow resulting in the position of the centrosome between the nucleus and the leading edge of the cell. GO:1990975 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990975 GO:1990976 protein transport along microtubule to mitotic spindle pole body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990976 The directed movement of a protein along a microtubule to the mitotic spindle pole body, mediated by motor proteins. GO:1990977 obsolete negative regulation of mitotic DNA replication initiation from late origin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990977 OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of firing from a late origin of replication involved in mitotic DNA replication. GO:1990981 obsolete regulation of protein localization to cell division site involved in cell separation after cytokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990981 OBSOLETE. A regulation of protein localization to cell division site involved in cell separation after cytokinesis. GO:1990982 obsolete Immune memory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990982 OBSOLETE. The immune response against a previously encountered antigen being quicker and quantitatively better compared with the primary response. GO:1990983 tRNA demethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990983 The removal of a methyl group from one or more residues within a tRNA molecule. GO:1990984 tRNA demethylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990984 Catalysis of the removal of a methyl group from one or more positions within a tRNA molecule. GO:0050811 GABA receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050811 gamma-aminobutyric acid receptor binding|4-aminobutanoate receptor binding|diazepam binding inhibitor activity|4-aminobutyrate receptor binding Interacting selectively and non-covalently with the gamma-aminobutyric acid (GABA, 4-aminobutyrate) receptor. GO:0050812 regulation of acyl-CoA biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050812 regulation of acyl-CoA formation|regulation of acyl-CoA biosynthesis|regulation of acyl-CoA anabolism|regulation of acyl-CoA synthesis Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acyl-CoA. GO:0050810 regulation of steroid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050810 regulation of steroid synthesis|regulation of steroid formation|regulation of steroid biosynthesis|regulation of steroidogenesis|regulation of steroid anabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. GO:1990980 obsolete copper ion transport across blood-CSF barrier biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990980 copper ion transport across blood-cerebrospinal fluid barrier|copper ion transport across BCB OBSOLETE. The directed movement of copper ions passing through the blood-cerebrospinal fluid barrier. GO:0050815 phosphoserine residue binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050815 phosphoserine binding Interacting selectively and non-covalently with a phosphorylated serine residue within a protein. GO:0050816 phosphothreonine residue binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050816 phosphothreonine binding Interacting selectively and non-covalently with a phosphorylated threonine residue within a protein. GO:0050813 epothilone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050813 epothilone metabolism The chemical reactions and pathways involving epothilone, a drug obtained from the myxobacteria Sporangium cellulosum that interferes with cell division. Some epothilones are being studied as treatments for cancer. CHEBI:37507 anthracenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37507 GO:0050814 epothilone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050814 epothilone biosynthesis|epothilone synthesis|epothilone formation|epothilone anabolism The chemical reactions and pathways resulting in the formation of epothilone, a drug obtained from the myxobacteria Sporangium cellulosum that interferes with cell division. Some epothilones are being studied as treatments for cancer. OPL:0000321 Mammalia macrophage biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OPL_0000321 A macrophage that is a part of or originated from a mammalia. GO:0050819 negative regulation of coagulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050819 down regulation of coagulation|negative regulation of clotting|downregulation of coagulation|anticoagulant activity|down-regulation of coagulation|inhibition of coagulation Any process that stops, prevents, or reduces the frequency, rate or extent of coagulation. CHEBI:86542 2-hydroxyhexanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86542 OPL:0000322 Trypanosomatida metacyclic stage biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OPL_0000322 A parasite lifecycle stage of trypanosomatidae in which the organism is infectious and does not multiply. CHEBI:86543 2-hydroxyoctanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86543 GO:0050817 coagulation biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0050817 clotting The process in which a fluid solution, or part of it, changes into a solid or semisolid mass. GO:0050818 regulation of coagulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050818 regulation of clotting Any process that modulates the frequency, rate or extent of coagulation, the process in which a fluid solution, or part of it, changes into a solid or semisolid mass. OPL:0000320 Mammalia blood biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OPL_0000320 Blood that is part of or originated from a mammalia. GO:1990985 obsolete apoptosis in response to oxidative stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990985 OBSOLETE. Any biological process that results in permanent cessation of all vital functions of a cell upon exposure to oxidative stress. GO:1990986 DNA recombinase disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990986 Rad51 nucleoprotein filament disassembly The disaggregation of a DNA recombinase complex into its constituent strand exchange proteins (recombinases). GO:0001895 retina homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001895 A tissue homeostatic process involved in the maintenance of an internal equilibrium within the retina of the eye, including control of cellular proliferation and death and control of metabolic function. GO:0001896 autolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001896 Wikipedia:Autolysis A programmed cell death process observed in bacteria and filamentous fungi and leading to spontaneous death by lysis. Examples are lysis of the mother cell during sporulation of Bacillus subtilis and self-degradation of fungal cells in Aspergillus nidulans. Autolysis is also involved in bacterial biofilm formation. GO:0001897 cytolysis by symbiont of host cells biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001897 cytolysis by organism of host cells The killing by an organism of a cell in its host organism by means of the rupture of cell membranes and the loss of cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0001898 regulation of cytolysis by symbiont of host cells biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001898 regulation by symbiont of cytolysis of host cells Any process in which an organism modulates the frequency, rate or extent of the cytolysis by that organism of cells in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0001891 phagocytic cup biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001891 An invagination of the cell membrane formed by an actin dependent process during phagocytosis. Following internalization it is converted into a phagosome. GO:0001892 embryonic placenta development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001892 fetal placenta development The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin. GO:0001893 maternal placenta development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001893 decidua development Maternally driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin. GO:0060190 negative regulation of protein desumoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060190 Any process that decreases the frequency, rate or extent of protein desumoylation. Protein desumoylation is the process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein. GO:0001894 tissue homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001894 tissue maintenance A homeostatic process involved in the maintenance of an internal steady state within a defined tissue of an organism, including control of cellular proliferation and death and control of metabolic function. GO:0060191 regulation of lipase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060191 Any process that modulates the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid. GO:0060192 negative regulation of lipase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060192 Any process that decreases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid. GO:1902379 chemoattractant activity involved in axon guidance biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1902379 chemoattractant activity involved in axon pathfinding|chemoattractant activity involved in axon growth cone guidance|chemoattractant activity involved in axon chemotaxis Any chemoattractant activity that is involved in axon guidance. GO:0060193 positive regulation of lipase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060193 Any process that increases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid. GO:0001890 placenta development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001890 placentation|placental development The process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin. GO:0060194 regulation of antisense RNA transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060194 Any process that modulates the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA. GO:0060195 negative regulation of antisense RNA transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060195 Any process that decreases the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA. GO:1902377 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902377 GO:1902378 VEGF-activated neuropilin signaling pathway involved in axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902378 VEGF-Npn-1 signaling involved in axon pathfinding|VEGF-Npn-1 signaling involved in axon growth cone guidance|VEGF-Npn-1 signaling involved in axon guidance|vascular endothelial growth factor-activated neuropilin signaling pathway involved in axon growth cone guidance|VEGF-activated neuropilin signaling pathway involved in axon pathfinding|vascular endothelial growth factor-activated neuropilin signaling pathway involved in axon pathfinding|vascular endothelial growth factor-activated neuropilin signaling pathway involved in axon guidance|VEGF-activated neuropilin signaling pathway involved in axon chemotaxis|vascular endothelial growth factor-activated neuropilin signaling pathway involved in axon chemotaxis|VEGF-Npn-1 signaling involved in axon chemotaxis|VEGF-activated neuropilin signaling pathway involved in axon growth cone guidance Any VEGF-activated neuropilin signaling pathway that is involved in axon guidance. GO:0060196 positive regulation of antisense RNA transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060196 Any process that increases the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA. GO:1902375 nuclear tRNA 3'-trailer cleavage, endonucleolytic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902375 tRNA 3'-end cleavage, endonucleolytic in nucleus|tRNA 3'-end cleavage, endonucleolytic in cell nucleus|endonucleolytic tRNA 3'-end cleavage in nucleus|tRNA 3'-trailer cleavage, endonucleolytic in cell nucleus|endonucleolytic tRNA 3'-trailer cleavage in nucleus|endonucleolytic tRNA 3'-trailer cleavage in cell nucleus|endonucleolytic tRNA 3'-end cleavage in cell nucleus Any tRNA 3'-trailer cleavage, endonucleolytic that takes place in nucleus. GO:0060197 cloacal septation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060197 cloaca septation The separation of the single opening of the digestive, urinary, and reproductive tracts, the cloaca, into multiple isolated openings during development. GO:1902376 obsolete protein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902376 protein denaturation involved in proteasomal ubiquitin-dependent protein degradation|protein denaturation involved in proteasomal pathway|protein denaturation involved in proteasomal ubiquitin-dependent protein breakdown|protein denaturation involved in proteasome pathway|protein denaturation involved in proteasomal processing|protein denaturation involved in proteasomal ubiquitin-dependent protein catabolism OBSOLETE. Any protein denaturation that is involved in proteasomal ubiquitin-dependent protein catabolic process. GO:0060198 clathrin-sculpted vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0060198 clathrin sculpted vesicle A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release. GO:1902384 glycyrrhetinate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902384 glycyrrhetinate metabolism The chemical reactions and pathways involving glycyrrhetinate. GO:0060199 clathrin-sculpted glutamate transport vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0060199 clathrin sculpted glutamate transport vesicle|clathrin sculpted glutamate constitutive secretory pathway transport vesicle A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing glutamate. GO:1902385 glycyrrhetinate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902385 glycyrrhetinate breakdown|glycyrrhetinate catabolism|glycyrrhetinate degradation The chemical reactions and pathways resulting in the breakdown of glycyrrhetinate. GO:1902382 11-oxo-beta-amyrin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902382 11-oxo-beta-amyrin catabolism|11-oxo-beta-amyrin degradation|11-oxo-beta-amyrin breakdown The chemical reactions and pathways resulting in the breakdown of 11-oxo-beta-amyrin. GO:1902383 11-oxo-beta-amyrin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902383 11-oxo-beta-amyrin biosynthesis|11-oxo-beta-amyrin anabolism|11-oxo-beta-amyrin synthesis|11-oxo-beta-amyrin formation The chemical reactions and pathways resulting in the formation of 11-oxo-beta-amyrin. GO:1990916 Isp3 layer of spore wall biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990916 The outermost layers of the spore wall, as described in Schizosaccharomyces pombe. GO:1902380 positive regulation of endoribonuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902380 up regulation of endoribonuclease activity|activation of endoribonuclease activity|up regulation of endonuclease G activity|positive regulation of endonuclease G activity|up-regulation of endoribonuclease activity|activation of endonuclease G activity|up-regulation of endonuclease G activity|upregulation of endoribonuclease activity|upregulation of endonuclease G activity Any process that activates or increases the frequency, rate or extent of endoribonuclease activity. GO:1902381 11-oxo-beta-amyrin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902381 11-oxo-beta-amyrin metabolism The chemical reactions and pathways involving 11-oxo-beta-amyrin. GO:1990917 ooplasm biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990917 The cytoplasm of an ovum. GO:1990918 double-strand break repair involved in meiotic recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990918 The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix that contributes to reciprocal meiotic recombination. GO:1990919 proteasome-nuclear membrane anchor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990919 nuclear membrane proteasome anchor|nuclear membrane proteasome adaptor|nuclear membrane proteasome tether|nuclear membrane proteasome tether activity|tethering factor for nuclear proteasome|nuclear membrane-proteasome tether activity|nuclear membrane-proteasome anchor activity The binding activity of a molecule that brings together a proteasome complex and a nuclear inner membrane, to maintain the nuclear membrane localization of the proteasome. GO:1990912 obsolete response to microwave radiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990912 OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a microwave radiation stimulus. GO:1990913 sperm head plasma membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990913 The plasma membrane that is part of the head section of a sperm cell. GO:1990914 integral component of periplasmic side of plasma membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990914 IntAct:EBI-11297444 The component of the plasma membrane consisting of the gene products that penetrate only the periplasmic side of the membrane. GO:1990915 structural constituent of ascospore wall biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990915 The action of a molecule that contributes to the structural integrity of an ascospore wall. GO:0001899 negative regulation of cytolysis by symbiont of host cells biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001899 down-regulation by symbiont of cytolysis of host cells|inhibition by symbiont of cytolysis of host cells|down regulation by symbiont of cytolysis of host cells|negative regulation by symbiont of cytolysis of host cells|downregulation by symbiont of cytolysis of host cells Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of cytolysis by that organism of cells in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:1990910 response to hypobaric hypoxia biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990910 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension combined with low atmospheric pressure. Hypoxia is defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95% and hypobaric is defined as atmospheric pressure below 0.74 atm (greater than 2,500 m above sea level). GO:1990911 response to psychosocial stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990911 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to aversive or demanding psychological and social conditions that tax or exceed the behavioral resources of the organism. GO:0060180 female mating behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060180 The specific behavior of a female organism that is associated with reproduction. GO:0060181 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0060181 GO:0060182 apelin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0060182 Combining with the peptide apelin to initiate a change in cell activity. GO:0060183 apelin receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060183 apelin receptor signalling pathway The series of molecular signals generated as a consequence of an apelin receptor binding to one of its physiological ligands. GO:0060184 cell cycle switching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060184 The process in which a cell switches cell cycle mode. GO:1902388 ceramide 1-phosphate transfer activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1902388 Reactome:R-HSA-5339535 intermembrane ceramide 1-phosphate transfer activity|ceramide 1-phosphate carrier activity|ceramide 1-phosphate transporter activity Removes a ceramide 1-phosphate from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. GO:1902389 ceramide 1-phosphate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902389 The directed movement of a ceramide 1-phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0060185 outer ear unfolding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060185 The opening and spreading out of the outer ear. GO:0060186 outer ear emergence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060186 ear extroversion|outer ear growth|ear elevation The growth of the outer ear. GO:1902386 glycyrrhetinate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902386 glycyrrhetinate anabolism|glycyrrhetinate synthesis|glycyrrhetinate formation|glycyrrhetinate biosynthesis The chemical reactions and pathways resulting in the formation of glycyrrhetinate. GO:0060187 cell pole biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0060187 Either of two different areas at opposite ends of an axis of a cell. GO:1902387 ceramide 1-phosphate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1902387 Interacting selectively and non-covalently with ceramide 1-phosphate. GO:1902395 regulation of 1-deoxy-D-xylulose-5-phosphate synthase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902395 regulation of 1-deoxy-D-xylulose-5-phosphate pyruvate-lyase (carboxylating) activity|regulation of 1-deoxyxylulose-5-phosphate synthase activity|regulation of DOXP synthase activity|regulation of pyruvate:D-glyceraldehyde-3-phosphate acetaldehydetransferase (decarboxylating)|regulation of DXP-synthase activity Any process that modulates the frequency, rate or extent of 1-deoxy-D-xylulose-5-phosphate synthase activity. GO:0060188 regulation of protein desumoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060188 Any process that modulates the frequency, rate or extent of protein desumoylation. Protein desumoylation is the process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein. GO:0060189 positive regulation of protein desumoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060189 Any process that increases the frequency, rate or extent of protein desumoylation. Protein desumoylation is the process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein. GO:1902396 protein localization to bicellular tight junction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902396 protein localisation in tight junction|protein localization in tight junction|protein localisation to tight junction A process in which a protein is transported to, or maintained in, a location within a bicellular tight junction. GO:1902393 negative regulation of exodeoxyribonuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902393 down regulation of exodeoxyribonuclease activity|downregulation of exodeoxyribonuclease activity|down-regulation of exodeoxyribonuclease activity|inhibition of exodeoxyribonuclease activity Any process that stops, prevents or reduces the frequency, rate or extent of exodeoxyribonuclease activity. GO:1902394 positive regulation of exodeoxyribonuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902394 upregulation of exodeoxyribonuclease activity|up regulation of exodeoxyribonuclease activity|activation of exodeoxyribonuclease activity|up-regulation of exodeoxyribonuclease activity Any process that activates or increases the frequency, rate or extent of exodeoxyribonuclease activity. GO:1902391 positive regulation of N-terminal peptidyl-serine acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902391 up regulation of N-terminal peptidyl-serine acetylation|upregulation of N-terminal peptidyl-serine acetylation|activation of N-terminal peptidyl-serine acetylation|up-regulation of N-terminal peptidyl-serine acetylation Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-serine acetylation. GO:1990927 calcium ion regulated lysosome exocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990927 The process of secretion by a cell that results in the release of intracellular molecules contained within a lysosome by fusion of the vesicle with the plasma membrane of a cell, induced by a rise in cytosolic calcium-ion levels. GO:1990928 response to amino acid starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990928 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of amino acids. GO:1902392 regulation of exodeoxyribonuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902392 Any process that modulates the frequency, rate or extent of exodeoxyribonuclease activity. GO:1990929 sulfoquinovosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990929 Catalyzes the hydrolysis of terminal non-reducing alpha-sulfoquinovoside residues in alpha-sulfoquinovosyl diacylglycerides and alpha-sulfoquinovosyl glycerol, generating alpha-sulfoquinovose. GO:1902390 regulation of N-terminal peptidyl-serine acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902390 Any process that modulates the frequency, rate or extent of N-terminal peptidyl-serine acetylation. GO:1990923 PET complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990923 A protein complex that is composed of at least EXD1, TDRD12 and some PIWI protein. The complex is required for MILI slicing-triggered biogenesis and loading of MIWI2 piRNAs. GO:1990924 obsolete amphisome membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990924 amphisomal membrane OBSOLETE. The lipid bilayer surrounding the amphisome and separating its contents from the cell cytoplasm. GO:1990925 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990925 GO:1990926 short-term synaptic potentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990926 synaptic facilitation The process by which synaptic transmission, induced by the arrival of a spike (action potential) at a synapse, acts to increase the amount of neurotransmitter released in response to the arrival of subsequent spikes. This effect is seen when a train of closely space spikes arrives at a synapse with a low initial release probability. It occurs in a timeframe of tens to hundreds of milliseconds. GO:1990920 proteasome localization to nuclear periphery biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990920 Any process in which the proteasome is transported to, or maintained at the nuclear periphery. GO:1990921 obsolete proteasome localization to nuclear periphery biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990921 proteasome localisation to nuclear periphery OBSOLETE. A process in which a proteasome is transported to, or maintained in, a location within the nuclear periphery. GO:1990922 hepatic stellate cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990922 Ito cell proliferation|hepatic perisinusoidal cell proliferation|perisinusoidal cell proliferation The multiplication or reproduction of hepatic stellate cells, resulting in the expansion of a hepatic stellate cell population. Hepatic stellate cells are found in the perisinusoidal space of the liver, and are capable of multiple roles including storage of retinol, presentation of antigen to T cells (including CD1d-restricted NKT cells), and upon activation, production of extracellular matrix components. This cell type comprises approximately 8-15% of total cells in the liver. GO:0001873 polysaccharide immune receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001873 polysaccharide receptor activity Combining with a polysaccharide and transmitting the signal to initiate an innate immune response. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. GO:0098785 biofilm matrix assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098785 A process that results in the assembly of a biofilm matrix. GO:0098786 biofilm matrix disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098786 A process that results in the disassembly of a biofilm matrix. GO:0001874 (1->3)-beta-D-glucan immune receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001874 (1->3)-beta-D-glucan receptor activity|beta-1,3-D-glucan receptor activity|(1,3)-beta-D-glucan receptor activity|1,3-beta-D-glucan receptor activity|zymosan receptor activity Combining with (1->3)-beta-D-glucans to initiate an innate immune response. GO:0098783 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0098783 GO:0001875 lipopolysaccharide immune receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001875 endotoxin receptor activity|lipopolysaccharide receptor activity|LPS receptor activity Combining with a lipopolysaccharide and transmitting the signal across the cell membrane to initiate an innate immune response. Lipopolysaccharides (LPS) are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system. GO:0098784 biofilm matrix organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098784 biofilm matrix organization and biogenesis A process that results in the assembly, arrangement of constituent parts, or disassembly of a biofilm matrix. GO:0001876 lipoarabinomannan binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001876 LAM binding Interacting selectively and non-covalently with lipoarabinomannan. GO:0098781 ncRNA transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098781 The transcription of non (protein) coding RNA from a DNA template. GO:0098782 mechanosensitived potassium channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098782 mechanically-gated potassium channel activity Enables the transmembrane transfer of a potassium ion by a channel that opens in response to a mechanical stress. GO:0001870 positive regulation of complement activation, lectin pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001870 positive regulation of complement cascade, lectin pathway|upregulation of complement activation, lectin pathway|up regulation of complement activation, lectin pathway|activation of complement activation, lectin pathway|stimulation of complement activation, lectin pathway|up-regulation of complement activation, lectin pathway Any process that activates or increases the frequency, rate or extent of complement activation by the lectin pathway. GO:0001871 obsolete pattern binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001871 pattern recognition activity OBSOLETE. Interacting selectively and non-covalently with a repeating or polymeric structure, such as a polysaccharide or peptidoglycan. GO:0001872 (1->3)-beta-D-glucan binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001872 1,3-beta-D-glucan binding|zymosan binding|callose binding Interacting selectively and non-covalently with (1->3)-beta-D-glucans. GO:0098780 response to mitochondrial depolarisation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098780 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) in response to the depolarization of one or more mitochondria. GO:1902399 detection of stimulus involved in G1 DNA damage checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902399 perception of stimulus involved in G1/S DNA damage checkpoint|stimulus sensing involved in G1 DNA damage checkpoint|perception of stimulus involved in G1 DNA damage checkpoint|stimulus detection involved in G1/S DNA damage checkpoint|stimulus detection involved in G1 DNA damage checkpoint|detection of stimulus involved in G1/S DNA damage checkpoint|stimulus sensing involved in G1/S DNA damage checkpoint Any detection of stimulus that is involved in G1 DNA damage checkpoint. GO:1902397 detection of stimulus involved in meiotic spindle checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902397 perception of stimulus involved in meiotic spindle checkpoint|stimulus detection involved in meiotic spindle checkpoint|stimulus sensing involved in meiotic spindle checkpoint Any detection of stimulus that is involved in meiotic spindle checkpoint. GO:1902398 intracellular signal transduction involved in meiotic spindle checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902398 intracellular signaling pathway involved in meiotic spindle checkpoint|intracellular signaling cascade involved in meiotic spindle checkpoint|signal transduction via intracellular signaling cascade involved in meiotic spindle checkpoint|signal transmission via intracellular cascade involved in meiotic spindle checkpoint|intracellular signal transduction pathway involved in meiotic spindle checkpoint|intracellular signaling chain involved in meiotic spindle checkpoint Any intracellular signal transduction that is involved in meiotic spindle checkpoint. GO:1990938 peptidyl-aspartic acid autophosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990938 aspartyl autophosphorylation|peptidyl-aspartate autophosphorylation The phosphorylation by a protein of one or more of its own aspartate amino acid residues, or an aspartate residue on an identical protein. GO:1990939 ATP-dependent microtubule motor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990939 Reactome:R-HSA-9610627 Catalysis of movement along a microtubule, coupled to the hydrolysis of ATP. GO:1990934 nucleolus-like body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990934 NLB|compact nucleolus|nucleolus-like body A nuclear compartment containing significant amounts of non-nucleolar, spliceosomal components. It is commonly found in germinal vesicle (GV) stage oocytes, and is similar to both nucleoli and sphere organelles. GO:1990935 splicing factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990935 Interacting selectively and non-covalently with any protein involved in the process of removing sections of the primary RNA transcript to form the mature form of the RNA. GO:1990936 vascular associated smooth muscle cell dedifferentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990936 vascular smooth muscle cell dedifferentiation The process in which a vascular smooth muscle cell (a non-striated, elongated, spindle-shaped cell found lining the blood vessels) loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors. GO:1990937 xylan acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990937 The addition of one or more acetyl groups to a xylan molecule. GO:0001877 lipoarabinomannan immune receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001877 LAM receptor activity|lipoarabinomannan receptor activity Combining with lipoarabinomannan and transmitting the signal to initiate an innate immune response. GO:1990930 RNA N1-methyladenosine dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990930 Catalysis of the oxidative demethylation of N1-methyladenosine RNA, with concomitant decarboxylation of 2-oxoglutarate and releases oxidized methyl group on N1-methyladenosine as formaldehyde. GO:0098789 pre-mRNA cleavage required for polyadenylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098789 cleavage and polyadenylylation specificity factor activity|pre-mRNA cleavage factor activity The targeted, endonucleolytic cleavage of a pre-mRNA, required for polyadenylation of the 3' end. This cleavage is directed by binding sites near the 3' end of the mRNA and leaves a 3' hydoxyl end which then becomes a target for adenylation. GO:1990931 RNA N6-methyladenosine dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990931 Catalysis of the oxidative demethylation of N6-methyladenosine RNA, with concomitant decarboxylation of 2-oxoglutarate and releases oxidized methyl group on N6-methyladenosine as formaldehyde. GO:0001878 response to yeast biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001878 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a yeast species. GO:1990932 5.8S rRNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990932 Interacting selectively and non-covalently with 5.8S ribosomal RNA, a eukaryotic ribosomal RNA which forms a complex with 28S RNA. GO:0098787 mRNA cleavage involved in mRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098787 Cleavage of an immature mRNA transcript to produce one or more more mature mRNA transcripts, prior to translation into polypeptide. GO:0001879 detection of yeast biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001879 The series of events in which a stimulus from a yeast is received and converted into a molecular signal. GO:0098788 dendritic knob biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098788 apical dendritic knob The terminal swelling of an apical dendrite of a ciliated olfactory receptor neuron. Each knob gives rise to 5 to 20 long delicate nonmotile cilia, which extend into the mucus covering the sensory epithelium. GO:1990933 microtubule cytoskeleton attachment to nuclear envelope biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990933 A process in which the microtubule cytoskeleton is attached to the nuclear envelope. GO:0001884 pyrimidine nucleoside binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001884 Interacting selectively and non-covalently with a pyrimidine nucleoside, a compound consisting of a pyrimidine base linked either to ribose or deoxyribose. GO:0098796 membrane protein complex biolink:CellularComponent go-plus goslim_metagenomics http://purl.obolibrary.org/obo/GO_0098796 Any protein complex that is part of a membrane. GO:0098797 plasma membrane protein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098797 Any protein complex that is part of the plasma membrane. GO:0001885 endothelial cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001885 The progression of an endothelial cell over time, from its formation to the mature structure. GO:0098794 postsynapse biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098794 The part of a synapse that is part of the post-synaptic cell. GO:0001886 endothelial cell morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001886 The change in form (cell shape and size) that occurs during the differentiation of an endothelial cell. GO:1990940 obsolete microtubule sliding involved in mitotic spindle elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990940 OBSOLETE. The movement of one microtubule along another microtubule involved in mitotic spindle elongation. GO:0098795 mRNA cleavage involved in gene silencing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098795 Cleavage of an mRNA occurring as part of the mechanism of gene silencing. GO:0001887 selenium compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001887 selenium metabolic process|selenium compound metabolism|selenium metabolism The chemical reactions and pathways involving compounds that contain selenium, such as selenocysteine. GO:0098792 xenophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098792 The selective autophagy process in which a region of cytoplasm containing an intracellular pathogen or some part of an intracellular pathogen (e.g. viral capsid) is enclosed in a double membrane bound autophagosome, which then fuses with the lysosome leading to degradation of the contents. GO:0001880 Mullerian duct regression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001880 The process in which the Mullerian ducts, primordia of the oviducts, uterus and upper vagina, undergo regression in male embryos. GO:0001881 receptor recycling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001881 The process that results in the return of receptor molecules to an active state and an active cellular location after they have been stimulated by a ligand. An active state is when the receptor is ready to receive a signal. CHEBI:144842 N(6)-methyl-AMP(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_144842 GO:0098793 presynapse biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098793 presynaptic terminal The part of a synapse that is part of the presynaptic cell. GO:0098790 ncRNA transcription associated with protein coding gene TSS/TES biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098790 pasRNA transcription The transcription of non-coding RNA associated with transcriptional start and end sites of protein coding genes. This occurs at some low level for many protein coding genes. GO:0001882 nucleoside binding biolink:MolecularActivity go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0001882 Interacting selectively and non-covalently with a nucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked either to ribose or deoxyribose. GO:0001883 purine nucleoside binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001883 Interacting selectively and non-covalently with a purine nucleoside, a compound consisting of a purine base linked either to ribose or deoxyribose. GO:0098791 Golgi apparatus subcompartment biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098791 Golgi subcompartment A compartment that consists of a lumen and an enclosing membrane, and is part of the Golgi apparatus. GO:1990949 metaphase/anaphase transition of meiosis I biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990949 first meiotic metaphase/anaphase transition|meiosis I metaphase/anaphase transition The cell cycle process in which a cell progresses from metaphase to anaphase as part of meiosis I. GO:1990945 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990945 GO:1990946 meiosis I/meiosis II transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990946 The cell cycle process in which a cell progresses from meiosis I to meiosis II. GO:1990947 exit from meiosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990947 meiotic exit Any process involved in the progression from anaphase/telophase of meiosis II to the creation of end products of meiosis, in which ploidy is reduced by half. GO:1990948 ubiquitin ligase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990948 APC-Cdc20 complex inhibitor activity|mitotic anaphase-promoting complex inhibitor activity Stops, prevents or reduces the activity of a ubiquitin ligase. GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001888 RHEA:16221|EC:2.4.1.223|MetaCyc:2.4.1.223-RXN alpha1,4-N-acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1,3)-beta-D-galactosyl-(1,3)-beta-D-galactosyl-(1,4)-beta-D-xylosyl-proteoglycan 4IV-alpha-N-acetyl-D-glucosaminyltransferase activity|glucuronosylgalactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity|alpha-N-acetylglucosaminyltransferase I activity|alpha-1,4-N-acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan 4IV-alpha-N-acetyl-D-glucosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan = UDP + alpha-N-acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan. GO:1990941 mitotic spindle kinetochore microtubule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990941 Any of the mitotic spindle microtubules that attach to the kinetochores of chromosomes by their plus ends, and maneuver the chromosomes during mitotic chromosome segregation. GO:1990942 mitotic metaphase chromosome recapture biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990942 microtubule sliding involved in kinetochore retrieval|microtubule sliding involved in metaphase chromosome retrieval to the spindle pole body|sister kinetochore recapture|kinetochore retrieval|microtubule sliding involved in mitotic metaphase chromosome recapture|metaphase chromosome retrieval to the spindle pole body|microtubule sliding involved in sister kinetochore recapture A mechanism to recapture 'lost' chromosomes (chromosomes which have become detached from the spindle) during metaphase of mitotic chromosome segregation. Chromosomes with unattached kinetochores are migrated along (non polar) spindle microtubules to the mitotic spindle pole body by a combination of microtubule depolymerisation and 'kinetochore sliding' (migration of the chromosome along the microtubule). The chromosome subsequently migrates along the polar spindle microtubule to the metaphase plate. GO:0001889 liver development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001889 The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes. GO:1990943 mating type region replication fork barrier binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990943 RTS1 element binding|RTS1 barrier binding Interacting selectively and non-covalently with the replication fork barrier found in the mating type region of fission yeast. GO:0098798 mitochondrial protein-containing complex biolink:CellularComponent go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0098798 mitochondrial protein complex A protein complex that is part of a mitochondrion. GO:0098799 outer mitochondrial membrane protein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098799 Any protein complex that is part of the outer mitochondrial membrane. GO:1990944 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990944 GO:0001851 complement component C3b binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001851 Interacting selectively and non-covalently with the C3b product of the complement cascade. GO:0001852 complement component iC3b binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001852 Interacting selectively and non-covalently with the iC3b product of the complement cascade. GO:0001853 complement component C3dg binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001853 Interacting selectively and non-covalently with the C3dg product of the complement cascade. GO:0001854 complement component C3d binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001854 Interacting selectively and non-covalently with the C3d product of the complement cascade. GO:0001850 complement component C3a binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001850 Interacting selectively and non-covalently with the C3a product of the complement cascade. CHEBI:144833 L-beta-ethynylserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_144833 CHEBI:37598 nitrogen mustard biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37598 CHEBI:37592 organic phosphonate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37592 GO:0001859 complement component C3dg receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001859 Combining with the C3dg product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0001855 complement component C4b binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001855 Interacting selectively and non-covalently with the C4b product of the classical complement cascade. GO:0001856 complement component C5a binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001856 Interacting selectively and non-covalently with the C5a product of the complement cascade. GO:0001857 complement component C1q receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001857 Combining with the C1q complex, a component of the classical complement cascade, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0001858 complement component iC3b receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001858 Combining with the iC3b product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0001862 collectin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001862 Interacting selectively and non-covalently with a collectin, a member of a group of structurally related pattern recognition molecules characterized by having a carbohydrate recognition domain of the C-type lectin family at the C-terminus and a collagenous domain at the N-terminus. GO:0001863 collectin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001863 Combining with a collectin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0001864 pentraxin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001864 Interacting selectively and non-covalently with a pentraxin, a member of a family of inflammatory proteins with a radially symmetric arrangement of five identical, noncovalently linked chains in a pentagonal array. GO:0001865 NK T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001865 natural T cell differentiation|NK T-cell differentiation|NT cell differentiation|NK T-lymphocyte differentiation|NK T cell development|NK T lymphocyte differentiation|natural killer T cell differentiation|NKT cell differentiation The process in which a precursor cell type acquires the specialized features of a NK T cell. GO:0001860 complement component C3d receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001860 Combining with the C3d product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0001861 complement component C4b receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001861 Combining with the C4b product of the classical complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0001866 NK T cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001866 NK T-cell proliferation|NT cell proliferation|NK T-lymphocyte proliferation|NK T lymphocyte proliferation|natural killer T cell proliferation|NKT cell proliferation|natural T cell proliferation The expansion of a NK T cell population by cell division. GO:0001867 complement activation, lectin pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001867 complement cascade, lectin pathway Any process involved in the activation of any of the steps of the lectin pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes. GO:0001868 regulation of complement activation, lectin pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001868 regulation of complement cascade, lectin pathway Any process that modulates the frequency, rate or extent of the lectin pathway of complement activation. GO:0001869 negative regulation of complement activation, lectin pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001869 downregulation of complement activation, lectin pathway|down-regulation of complement activation, lectin pathway|inhibition of complement activation, lectin pathway|negative regulation of complement cascade, lectin pathway|down regulation of complement activation, lectin pathway Any process that stops, prevents, or reduces the rate of complement activation by the lectin pathway. GO:0001830 trophectodermal cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001830 trophectoderm cell fate commitment The cell fate commitment of precursor cells that will become trophectoderm cells. GO:0001831 trophectodermal cellular morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001831 trophectoderm cellular morphogenesis The morphogenesis of trophectoderm cells. GO:0001832 blastocyst growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001832 An increase in size of a blastocyst due to expansion of the blastocoelic cavity cell shape changes and cell proliferation. CHEBI:37578 halide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37578 CHEBI:62501 folate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62501 CHEBI:37579 acyl halide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37579 CHEBI:37576 gallate ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37576 CHEBI:37577 heteroatomic molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37577 CHEBI:62500 methacrylyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62500 CHEBI:62505 demethylspheroidene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62505 GO:0001837 epithelial to mesenchymal transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001837 epithelial-mesenchymal transition|mesenchymal cell differentiation from epithelial cell|EMT A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. CHEBI:62509 2-O-(alpha-D-glucopyranosyl)-D-glyceric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62509 GO:0001838 embryonic epithelial tube formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001838 The morphogenesis of an embryonic epithelium into a tube-shaped structure. GO:0001839 neural plate morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001839 The process in which the anatomical structures of the neural plate are generated and organized. The neural plate is a specialized region of columnar epithelial cells in the dorsal ectoderm that will give rise to nervous system tissue. CHEBI:62508 eudesmane sesquiterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62508 GO:0001833 inner cell mass cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001833 The proliferation of cells in the inner cell mass. CHEBI:37574 thiamine(1+) monophosphate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37574 GO:0001834 trophectodermal cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001834 trophectoderm cell proliferation The proliferation of cells in the trophectoderm. CHEBI:144817 2-ammonio-2-deoxy-D-galactopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_144817 CHEBI:37575 thiamine(1+) monophosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37575 GO:0001835 blastocyst hatching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001835 The hatching of the cellular blastocyst from the zona pellucida. CHEBI:37573 (2R)-DIMBOA glucoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37573 GO:0001836 release of cytochrome c from mitochondria biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001836 The process that results in the movement of cytochrome c from the mitochondrial intermembrane space into the cytosol, which is part of the apoptotic signaling pathway and leads to caspase activation. GO:0001840 neural plate development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001840 The process whose specific outcome is the progression of the neural plate over time, from its formation to the mature structure. The neural plate is a flat, thickened layer of ectodermal cells. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system. GO:0001841 neural tube formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001841 Wikipedia:Neurulation neurulation|neural tube morphogenesis The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system. GO:0001842 neural fold formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001842 neural groove formation The process in which the neural fold is formed. The edges of the neural plate thicken and move up to form a U-shaped structure called the neural groove. GO:0001843 neural tube closure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001843 The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline. GO:1990909 Wnt signalosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990909 LRP5/6 signalosome|Wnt signalosome complex|LRP6 signalosome|Wnt-LRP5/6 signalosome A multiprotein protein complex containing membrane-localized Wnt receptors and cytosolic protein complexes, which is capable of transmitting the Wnt signal. Contains at least a Wnt protein, LRP5 or LRP6, a member of the Frizzled (Fz) family, Axin and and a Dishevelled (DVL) protein. CHEBI:62510 2-O-(alpha-D-glucopyranosyl)-D-glycerate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62510 CHEBI:37588 phosphonic acid derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37588 GO:1990905 dinoflagellate peduncle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990905 A small, flexible, finger-like projection of cytoplasm containing an array of microtubles and located near the flagellar pores in some photosynthetic as well as nonphotosynthetic dinoflagellate species. Its functions are not fully understood, but it has been associated with feeding behavior (phagotrophy). GO:1990906 accessory outer segment biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990906 A cilium-like cell projection emanating from the inner segment and running alongside the outer segment of photoreceptors. CHEBI:62517 tricarballylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62517 GO:1990907 beta-catenin-TCF complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990907 IntAct:EBI-11425837|IntAct:EBI-11424678 beta-catenin/LEF complex|beta-catenin/lymphoid enhancer binding factor complex|beta-catenin/T-cell factor complex A protein complex that contains beta-catenin and a member of the T-cell factor (TCF)/lymphoid enhancer binding factor (LEF) family of transcription factors. CHEBI:62514 10-epi-gamma-eudesmol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62514 GO:1990908 obsolete Lys63-specific zinc metallopeptidase deubiquitinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990908 OBSOLETE. Hydrolysis of Lys63-Linked ubiquitin unit(s) from a ubiquitinated protein by a mechanism where zinc acts as the nucleophile. GO:1990901 old cell pole biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990901 The cell pole distal from the most recent cell division. GO:0001848 complement binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001848 Interacting selectively and non-covalently with any component or product of the complement cascade. CHEBI:37581 gamma-lactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37581 GO:0001849 complement component C1q complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001849 Interacting selectively and non-covalently with the C1q complex, a component of the classical complement cascade. GO:1990902 new cell pole biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990902 The cell pole proximal to the most recent cell division. GO:1990903 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990903 GO:1990904 ribonucleoprotein complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_1990904 Wikipedia:Ribonucleoprotein ribonucleoprotein complex|extracellular ribonucleoprotein complex|RNP|RNA-protein complex|protein-RNA complex|intracellular ribonucleoprotein complex A macromolecular complex that contains both RNA and protein molecules. CHEBI:62519 (2S,3S,5R,10R,12S,14S,15R,16R)-2-amino-12,16-dimethylicosane-3,5,10,14,15-pentol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62519 GO:0001844 protein insertion into mitochondrial membrane involved in apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001844 insertion of proteins into mitochondrial membranes during the induction of apoptosis|protein insertion into mitochondrial membrane involved in induction of apoptosis|protein insertion into mitochondrion membrane during induction of apoptosis|protein insertion into mitochondrial membrane during induction of apoptosis The process in which a protein is incorporated into a mitochondrial membrane as the initial phase of the mitochondrial membrane permeabilization that takes place in the apoptotic signaling pathway. GO:0001845 phagolysosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001845 late phagosome biosynthesis|phagolysosome formation|late phagosome formation The process that results in the fusion of a phagosome, a vesicle formed by phagocytosis, with a lysosome. CHEBI:37586 sodium phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37586 GO:0001846 opsonin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001846 Interacting selectively and non-covalently with an opsonin, such as a complement component or antibody, deposited on the surface of a bacteria, virus, immune complex, or other particulate material. CHEBI:37584 nicotinic acid dinucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37584 GO:1990900 ciliary pocket collar biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990900 flagellum pocket collar|FPC|flagellar pocket collar|flagellar collar|flagellar pore|cilium pocket collar A constriction site at the junction of the plasma, flagellar and flagellar pocket membranes where the flagellum emerges from the cell body. Observed in some unicellular eukaryotic species such as Chlamydomonas, Giardia and Trypanosoma. GO:0001847 opsonin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001847 Combining with an opsonin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0050785 advanced glycation end-product receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050785 RAGE activity|AGE receptor activity Combining with advanced glycation end-products and transmitting the signal to initiate a change in cell activity. Advanced glycation end-products (AGEs) form from a series of chemical reactions after an initial glycation event (a non-enzymatic reaction between reducing sugars and free amino groups of proteins). GO:0098720 succinate import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098720 succinate import into cell The directed movement of succinate from outside of a cell, across the plasma membrane and into the cytosol. GO:0050786 RAGE receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050786 advanced glycation end-product receptor binding Interacting selectively and non-covalently with the RAGE receptor, the receptor for advanced glycation end-products. GO:0050783 cocaine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050783 cocaine metabolism The chemical reactions and pathways involving cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic. GO:0050784 cocaine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050784 cocaine degradation|cocaine catabolism|cocaine breakdown The chemical reactions and pathways resulting in the breakdown of cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic. GO:0050789 regulation of biological process biolink:BiologicalProcess go-plus goslim_candida|gocheck_do_not_annotate|goslim_pir|goslim_aspergillus http://purl.obolibrary.org/obo/GO_0050789 regulation of physiological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. GO:0050787 detoxification of mercury ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050787 Any process that reduce or remove the toxicity of mercuric ion. These include transport of mercury away from sensitive areas and to compartments or complexes whose purpose is sequestration of mercury ion and/or reduction of mercury ion (Hg[II]) to metallic mercury (Hg[0]). GO:0050788 sequestering of mercury biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050788 mercury (Hg) ion sequestering|mercury (Hg) ion sequestration|retention of mercury (Hg2+) ion|sequestering of mercury (Hg) ion|sequestration of mercuric ion (Hg2+)|mercuric ion (Hg2+) sequestering|storage of mercury (Hg2+) ion|mercury (Hg2+) ion retention|mercury (Hg2+) ion storage|mercuric ion (Hg2+) sequestration|sequestration of mercury (Hg) ion|sequestering of mercuric ion (Hg2+) The process of binding or confining toxic mercury ions or atoms such that they are separated from sensitive components of a biological system. GO:2001314 UDP-4-deoxy-4-formamido-beta-L-arabinopyranose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001314 UDP-4-deoxy-4-formamido-beta-L-arabinopyranose catabolism|UDP-4-deoxy-4-formamido-beta-L-arabinopyranose degradation|UDP-4-deoxy-4-formamido-beta-L-arabinopyranose breakdown The chemical reactions and pathways resulting in the breakdown of a UDP-4-deoxy-4-formamido-beta-L-arabinopyranose. GO:2001315 UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001315 UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthesis|UDP-4-deoxy-4-formamido-beta-L-arabinopyranose anabolism|UDP-4-deoxy-4-formamido-beta-L-arabinopyranose synthesis|UDP-4-deoxy-4-formamido-beta-L-arabinopyranose formation The chemical reactions and pathways resulting in the formation of a UDP-4-deoxy-4-formamido-beta-L-arabinopyranose. GO:2001316 kojic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001316 C6H6O4 metabolic process|C6H6O4 metabolism|5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one metabolic process|5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one metabolism|kojic acid metabolism The chemical reactions and pathways involving kojic acid. GO:2001317 kojic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001317 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|C6H6O4 biosynthetic process|C6H6O4 biosynthesis|C6H6O4 anabolism|C6H6O4 synthesis|kojic acid anabolism|5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|C6H6O4 formation|kojic acid synthesis|5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|kojic acid biosynthesis|kojic acid formation The chemical reactions and pathways resulting in the formation of kojic acid. GO:0060110 basal layer of collagen and cuticulin-based cuticle extracellular matrix biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0060110 basal layer of collagen and cuticulin-based exoskeleton extracellular matrix The layer of cuticle most closely apposed to the hypodermal cells. The morphology of the basal layer varies with life stage. In adult C. elegans animals, the basal layers is comprised of three sublayers: two fibrous layers whose fibers run in clockwise and counter-clockwise directions meeting one another at a 60 degree angle, and an amorphous basal layer that lies underneath the fibrous layers and directly contacts the hypodermis. In C. elegans dauer and L1 larval stage animals, the basal layer is characterized by a striated pattern that appears to derive from interwoven laminae. An example of this component is found in Caenorhabditis elegans. GO:0035144 anal fin morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035144 The process in which the anatomical structures of the anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming. GO:0060111 alae of collagen and cuticulin-based cuticle extracellular matrix biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0060111 alae of collagen and cuticulin-based exoskeleton extracellular matrix Raised, thickened cuticular ridges that run longitudinally, and in parallel, along the left and right sides of the animal. The alae lie above the hypodermal cells known as the lateral seam cells. In C. elegans, alae are produced in L1 larvae, dauer larvae and adult stage animals, where they consist of three, five, and three ridges of distinct morphology, respectively. GO:0060112 generation of ovulation cycle rhythm biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060112 generation of menstrual cycle rhythm|generation of estrus cycle rhythm|generation of oestrus cycle rhythm The process which controls the timing of the type of sexual cycle seen in female mammals. GO:0035145 exon-exon junction complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035145 exon junction complex|EJC A multi-subunit complex deposited by the spliceosome upstream of messenger RNA exon-exon junctions. The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay. GO:0060113 inner ear receptor cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060113 inner ear hair cell differentiation The process in which relatively unspecialized cells, acquire specialized structural and/or functional features of inner ear receptor cells. Inner ear receptor cells are mechanorecptors found in the inner ear responsible for transducing signals involved in balance and sensory perception of sound. GO:0035146 tube fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035146 The joining of specific branches of a tubular system to form a continuous network. GO:0060114 vestibular receptor cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060114 vestibular hair cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a vestibular hair cell. GO:0035147 branch fusion, open tracheal system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035147 tracheal branch fusion Fusing of specific tracheal branches in an open tracheal system to branches from neighboring hemisegments to form a continuous tracheal network. Branch fusion is mediated by individual cells at the tip of each branch, which contact a similar cell and undergo a coordinated series of morphogenetic events that create a bicellular fusion joint. GO:2001310 gliotoxin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001310 gliotoxin formation|gliotoxin biosynthesis|gliotoxin anabolism|gliotoxin synthesis The chemical reactions and pathways resulting in the formation of the epipolythiodioxopiperazine gliotoxin, a poisonous substance produced by some species of fungi. GO:0060115 vestibular receptor cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060115 vestibular hair cell fate commitment The process in which a cell becomes committed to become a vestibular receptor cell. GO:0035148 tube formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035148 lumen formation in an anatomical structure|tube lumen formation Creation of the central hole of a tube in an anatomical structure through which gases and/or liquids flow. GO:0060116 vestibular receptor cell morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060116 vestibular hair cell morphogenesis Any process that alters the size or shape of a vestibular receptor cell. GO:2001311 lysobisphosphatidic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001311 bis(monoacylglycerol) hydrogen phosphate metabolism|bis(monoacylglycerol) hydrogen phosphate metabolic process|LBPA metabolism|bis(monoacylglycerol) hydrogen phosphate (BMP) metabolism|bis(monoacylglycerol) hydrogen phosphate (BMP) metabolic process|lysobisphosphatidic acid metabolism|LBPA metabolic process The chemical reactions and pathways involving a lysobisphosphatidic acid. A lysobisphosphatidic acid is a lysophosphatidic acid having the unusual property of a phosphodiester moiety linked to positions sn-1 and sn1' of glycerol; and two additional fatty acids esterified to the glycerol head group. GO:0035149 lumen formation, open tracheal system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035149 tracheal lumen formation Creation of the central hole of a tube in an open tracheal system through which gases flow. GO:2001312 lysobisphosphatidic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001312 bis(monoacylglycerol) hydrogen phosphate biosynthetic process|bis(monoacylglycerol) hydrogen phosphate biosynthesis|bis(monoacylglycerol) hydrogen phosphate (BMP) anabolism|LBPA biosynthesis|LBPA biosynthetic process|bis(monoacylglycerol) hydrogen phosphate (BMP) synthesis|LBPA anabolism|bis(monoacylglycerol) hydrogen phosphate (BMP) formation|bis(monoacylglycerol) hydrogen phosphate (BMP) biosynthetic process|bis(monoacylglycerol) hydrogen phosphate (BMP) biosynthesis|LBPA synthesis|bis(monoacylglycerol) hydrogen phosphate anabolism|LBPA formation|lysobisphosphatidic acid anabolism|bis(monoacylglycerol) hydrogen phosphate synthesis|bis(monoacylglycerol) hydrogen phosphate formation|lysobisphosphatidic acid synthesis|lysobisphosphatidic acid formation|lysobisphosphatidic acid biosynthesis The chemical reactions and pathways resulting in the formation of a lysobisphosphatidic acid. A lysobisphosphatidic acid is a lysophosphatidic acid having the unusual property of a phosphodiester moiety linked to positions sn-1 and sn1' of glycerol; and two additional fatty acids esterified to the glycerol head group. GO:0060117 auditory receptor cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060117 auditory hair cell development The process whose specific outcome is the progression of an auditory receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. GO:0098729 germline stem cell symmetric division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098729 Division of a germline stem cell to produce two germline stem cells of the same type as the parent. GO:2001313 UDP-4-deoxy-4-formamido-beta-L-arabinopyranose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001313 UDP-4-deoxy-4-formamido-beta-L-arabinopyranose metabolism The chemical reactions and pathways involving a UDP-4-deoxy-4-formamido-beta-L-arabinopyranose. GO:0060118 vestibular receptor cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060118 vestibular hair cell development The process whose specific outcome is the progression of a vestibular receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. GO:0098727 maintenance of cell number biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098727 Any process by which the numbers of cells of a particular type or in a tissue are maintained. GO:0060119 inner ear receptor cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060119 inner ear hair cell development The process whose specific outcome is the progression of an inner ear receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. GO:0098728 germline stem cell asymmetric division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098728 The self-renewing division of a germline stem cell, to produce a daughter stem cell and a daughter germ cell which will divide to form one or more gametes. GO:0098725 symmetric cell division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098725 Cell division in which both daughter cells are of the same type. GO:0098726 symmetric division of skeletal muscle satellite stem cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098726 The symmetric division of a skeletal muscle satellite stem cell, resulting in two skeletal muscle satellite stem cells. This process is involved in amplification of the pool of these cells. GO:0098723 skeletal muscle myofibril biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098723 A myofibril of a skeletal muscle fiber. GO:0050781 ortho-trichlorophenol reductive dehalogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050781 2,4,6-TCP reductive dehalogenase activity|2,4,6-trichlorophenol reductive dehalogenase activity Catalysis of the reaction: 2,4,6-trichlorophenol + 2 H+ + 2 e- = 2,4-dichlorophenol + HCl. GO:0035140 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035140 GO:0035141 medial fin morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035141 median fin morphogenesis|unpaired fin morphogenesis The process in which the anatomical structures of the medial fin are generated and organized. A medial fin is an unpaired fin of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming. GO:0050782 galactose uniporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050782 galactose, glucose uniporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose (out) = galactose(in). GO:0098724 symmetric stem cell division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098724 Symmetric division of a stem cell to produce two stem cells of the same type as the parent. Symmetric stem cell division is necessary for amplification of stem cell populations in the absence of sources of stem cells external to an existing population. GO:0098721 uracil import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098721 uracil import into cell The directed movement of uracil from outside of a cell, across the plasma membrane and into the cytosol. GO:0035142 dorsal fin morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035142 The process in which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins. GO:0098722 asymmetric stem cell division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098722 Division of a stem cell during which it retains its identity and buds off a daughter cell with a new identity. GO:0035143 caudal fin morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035143 The process in which the anatomical structures of the caudal fin are generated and organized. A caudal fin is an unpaired medial fin mounted at the caudal end of the fish, and is the main fin used for propulsion. GO:0050780 dopamine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050780 Interacting selectively and non-covalently with a dopamine receptor. GO:0050796 regulation of insulin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050796 Any process that modulates the frequency, rate or extent of the regulated release of insulin. GO:0098730 male germline stem cell symmetric division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098730 The symmetric division of a male germline stem cell to produce two male germline stem cells. An example of this is found in mammalian spermatogonial stem cells, some proportion of which divide symmetrically, so amplifying the population. The choice between asymmetric and symmetric division in this case appears to be internal and stochastic. GO:0050797 thymidylate synthase (FAD) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050797 MetaCyc:RXN-8850|KEGG_REACTION:R06613|EC:2.1.1.148|RHEA:29043 flavin dependent thymidylate synthase activity|ThyX activity|FDTS activity|5,10-methylenetetrahydrofolate,FADH2:dUMP C-methyltransferase activity|Thy1 activity Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP + NADPH + H+ = dTMP + tetrahydrofolate + NADP+. GO:0098731 skeletal muscle satellite stem cell maintenance involved in skeletal muscle regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098731 Any process by which the number of skeletal muscle satellite stem cells in a skeletal muscle is maintained during skeletal muscle regeneration. There are at least two mechanisms by which this is achieved. Skeletal muscle satellite stem cell asymmetric division ensures satellite stem cell numbers are kept constant. Symmetric division of these cells amplifies the number of skeletal muscle satellite stem cells. GO:0050794 regulation of cellular process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular physiological process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. GO:0050795 regulation of behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050795 regulation of behaviour Any process that modulates the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli. GO:1902308 regulation of peptidyl-serine dephosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902308 Any process that modulates the frequency, rate or extent of peptidyl-serine dephosphorylation. GO:1902309 negative regulation of peptidyl-serine dephosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902309 down-regulation of peptidyl-serine dephosphorylation|inhibition of peptidyl-serine dephosphorylation|down regulation of peptidyl-serine dephosphorylation|downregulation of peptidyl-serine dephosphorylation Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-serine dephosphorylation. GO:1902306 negative regulation of sodium ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902306 inhibition of sodium ion transmembrane transport|down regulation of sodium ion membrane transport|downregulation of sodium ion membrane transport|down-regulation of sodium ion transmembrane transport|down-regulation of sodium ion membrane transport|negative regulation of sodium ion membrane transport|downregulation of sodium ion transmembrane transport|inhibition of sodium ion membrane transport|down regulation of sodium ion transmembrane transport Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transport. GO:0050798 activated T cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050798 proliferation of activated T cells|activated T-cell proliferation|activated T-lymphocyte proliferation|activated T lymphocyte proliferation The expansion of a T cell population following activation by an antigenic stimulus. GO:1902307 positive regulation of sodium ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902307 upregulation of sodium ion transmembrane transport|upregulation of sodium ion membrane transport|up-regulation of sodium ion transmembrane transport|activation of sodium ion transmembrane transport|up regulation of sodium ion membrane transport|positive regulation of sodium ion membrane transport|activation of sodium ion membrane transport|up regulation of sodium ion transmembrane transport|up-regulation of sodium ion membrane transport Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transport. GO:0050799 cocaine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050799 cocaine biosynthesis|cocaine anabolism|cocaine synthesis|cocaine formation The chemical reactions and pathways resulting in the formation of cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic. GO:1902304 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902304 GO:1902305 regulation of sodium ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902305 regulation of sodium ion membrane transport Any process that modulates the frequency, rate or extent of sodium ion transmembrane transport. GO:1902302 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902302 GO:1902303 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902303 GO:1902300 galactarate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902300 D-galactarate transport|galactaric acid anion transport|galactarate transport The process in which galactaric acid anion (galactarate) is transported across a lipid bilayer, from one side of a membrane to the other. GO:1902301 galactarate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1902301 D-galactarate transmembrane transporter activity|galactaric acid anion transmembrane transporter activity Enables the transfer of galactaric acid anion (galactarate) from one side of a membrane to the other. GO:0060100 positive regulation of phagocytosis, engulfment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060100 Any process that activates or increases the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis. GO:0035133 post-embryonic caudal fin morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035133 The process, occurring after embryonic development, by which the anatomical structures of the caudal fin are generated and organized. The caudal fin is an unpaired medial fin mounted at the caudal end of the fish and is the main fin used for propulsion. GO:0060101 negative regulation of phagocytosis, engulfment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060101 Any process that stops, prevents, or reduces the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis. GO:0035134 post-embryonic dorsal fin morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035134 The process, occurring after embryonic development, by which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of a fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins. GO:0060102 collagen and cuticulin-based cuticle extracellular matrix biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0060102 collagen and cuticulin-based exoskeleton extracellular matrix A collagen and cuticulin-based noncellular, multilayered structure that is synthesized by an underlying ectodermal (hypodermal) cell layer. The cuticle serves essential functions in body morphology, locomotion, and environmental protection. An example of this component is found in Caenorhabditis elegans. GO:0035135 post-embryonic anal fin morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035135 The process, occurring after embryonic development, by which the anatomical structures of the anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming. GO:0060103 obsolete collagen and cuticulin-based cuticle extracellular matrix part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0060103 OBSOLETE. Any constituent part of the collagen and cuticulin-based cuticle extracellular matrix, a collagen and cuticulin-based noncellular, multilayered structure that is synthesized by an underlying ectodermal (hypodermal) cell layer. GO:0035136 forelimb morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035136 arm morphogenesis The process in which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human. GO:0060104 surface coat of collagen and cuticulin-based cuticle extracellular matrix biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0060104 surface coat of collagen and cuticulin-based exoskeleton extracellular matrix An electron dense, amorphous envelope that comprises the outermost layer of the cuticle. The surface coat is loosely apposed to the epicuticle, has distinct biochemical properties, is synthesized by cells other than the underlying hypodermis, and is labile. In addition to serving as a lubricant to protect against abrasion and dehydration, the surface coat may also play important roles in infection and immune evasion. An example of this component is found in Caenorhabditis elegans. GO:0035137 hindlimb morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035137 The process in which the anatomical structures of the hindlimb are generated and organized. GO:0060105 epicuticle of collagen and cuticulin-based cuticle extracellular matrix biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0060105 epicuticle of collagen and cuticulin-based exoskeleton extracellular matrix A lipid-containing layer of cuticle that lies between the cortical layer and the surface coat. An example of this component is found in Caenorhabditis elegans. GO:0035138 pectoral fin morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035138 The process in which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion. GO:0035139 pelvic fin morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035139 The process in which the anatomical structures of the pelvic fin are generated and organized. Pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion. GO:0060106 cortical layer of collagen and cuticulin-based cuticle extracellular matrix biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0060106 The cuticle layer that lies directly beneath the lipid-containing epicuticle. The cortical layer contains collagens and insoluble, non-collagenous cuticulins and is characterized by a distinct annular pattern consisting of regularly spaced annular ridges delineated by annular furrows. An example of this component is found in Caenorhabditis elegans. GO:0060107 annuli extracellular matrix biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0060107 annulae|annulus|annule(s)|annular rings The extracellular matrix that is a regularly spaced circumferential ridge present in the cortical region of the cuticle. Annuli are delineated by annular furrows and are present throughout the cuticle with the exception of lateral regions where longitudinal alae are present. GO:0060108 annular furrow extracellular matrix biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0060108 The extracellular matrix part that is a regularly spaced indentation in the outer cortical layer of the cuticle. The pattern of annular furrows corresponds to sites of invaginations in hypodermal cell membranes that, in turn, correspond to submembranous regions where actin microfilament bundles assemble early in lethargus, the first phase of the molting cycle in which activity and feeding decline. GO:0098738 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0098738 GO:0060109 medial layer of collagen and cuticulin-based cuticle extracellular matrix biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0060109 medial layer struts The fluid-filled cuticle layer that lies between the cortical and basal layers and is characterized by the presence of regularly spaced columnar struts that lie on either side of the annular furrows and link the two surrounding layers. In C. elegans, a defined medial layer is found only in adult animals. GO:0098739 import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098739 uptake The directed movement of some substance from outside of a cell, across the plasma membrane and into the cytosol. GO:0098736 negative regulation of the force of heart contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098736 Any process that decreases the force of heart muscle contraction. GO:0098737 protein insertion into plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098737 The process that results in the incorporation of a protein into a plasma membrane. Incorporation in this context means having some part or covalently attached group that is inserted into the the hydrophobic region of one or both bilayers. GO:0050792 regulation of viral process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050792 regulation of viral process|regulation of viral reproduction Any process that modulates the rate or extent of the viral life cycle, the set of processes by which a virus reproduces and spreads among hosts. GO:0098734 macromolecule depalmitoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098734 The removal of palymitoyl groups from a macromolecule. GO:0035130 post-embryonic pectoral fin morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035130 The process, occurring after embryonic development, by which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion. GO:0050793 regulation of developmental process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050793 Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). GO:0098735 positive regulation of the force of heart contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098735 Any process that increases the force of heart muscle contraction. GO:0050790 regulation of catalytic activity biolink:BiologicalProcess go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0050790 regulation of enzyme activity|regulation of metalloenzyme activity Any process that modulates the activity of an enzyme. GO:0035131 post-embryonic pelvic fin morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035131 The process, occurring after embryonic development, by which the anatomical structures of the pelvic fin are generated and organized. The pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion. GO:0098732 macromolecule deacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098732 The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a macromolecule. GO:0098733 hemidesmosome associated protein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098733 Any protein complex that is part of or has some part in a hemidesmosome. GO:0035132 post-embryonic medial fin morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035132 post-embryonic unpaired fin morphogenesis The process, occurring after embryonic development, by which the anatomical structures of the medial fin are generated and organized. Medial fins are unpaired fins of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming. GO:0050791 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050791 GO:1902319 DNA strand elongation involved in nuclear cell cycle DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902319 DNA strand elongation involved in DNA replication involved in S phase|DNA strand elongation involved in DNA replication involved in S-phase|DNA strand elongation involved in DNA replication during S phase Any DNA strand elongation that is involved in nuclear cell cycle DNA replication. GO:1902317 nuclear DNA replication termination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902317 DNA replication termination involved in DNA replication during S phase|DNA replication termination involved in DNA replication involved in S phase|DNA replication termination involved in nuclear cell cycle DNA replication|DNA replication termination involved in DNA replication involved in S-phase Any DNA replication termination that is involved in nuclear cell cycle DNA replication. GO:1902318 synthesis of RNA primer involved in nuclear cell cycle DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902318 replication priming involved in DNA replication involved in S-phase|replication priming involved in DNA replication during S phase|DNA replication, synthesis of RNA primer involved in DNA replication involved in S phase|replication priming involved in nuclear cell cycle DNA replication|DNA replication, synthesis of RNA primer involved in DNA replication during S phase|DNA replication, synthesis of RNA primer involved in DNA replication involved in S-phase|replication priming involved in DNA replication involved in S phase Any synthesis of RNA primer that is involved in nuclear cell cycle DNA replication. GO:1902315 nuclear cell cycle DNA replication initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902315 DNA replication initiation involved in nuclear cell cycle DNA replication|DNA endoreduplication initiation involved in nuclear cell cycle DNA replication|DNA re-replication initiation involved in nuclear cell cycle DNA replication Any DNA replication initiation that is involved in nuclear cell cycle DNA replication. GO:1902316 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902316 GO:1902313 positive regulation of copper ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902313 positive regulation of copper ion membrane transport|up regulation of copper ion transmembrane transport|up-regulation of copper cation transmembrane transport|up-regulation of copper ion membrane transport|upregulation of copper ion transmembrane transport|upregulation of copper cation transmembrane transport|upregulation of copper ion membrane transport|up-regulation of copper ion transmembrane transport|activation of copper ion transmembrane transport|up regulation of copper cation transmembrane transport|activation of copper cation transmembrane transport|positive regulation of copper cation transmembrane transport|up regulation of copper ion membrane transport|activation of copper ion membrane transport Any process that activates or increases the frequency, rate or extent of copper ion transmembrane transport. GO:1902314 hydroquinone binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1902314 quinol binding Interacting selectively and non-covalently with hydroquinone. GO:1902311 regulation of copper ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902311 regulation of copper cation transmembrane transport|regulation of copper ion membrane transport Any process that modulates the frequency, rate or extent of copper ion transmembrane transport. GO:1902312 negative regulation of copper ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902312 down-regulation of copper cation transmembrane transport|negative regulation of copper cation transmembrane transport|negative regulation of copper ion membrane transport|down-regulation of copper ion membrane transport|downregulation of copper ion transmembrane transport|inhibition of copper cation transmembrane transport|inhibition of copper ion membrane transport|down regulation of copper ion transmembrane transport|inhibition of copper ion transmembrane transport|down regulation of copper cation transmembrane transport|down regulation of copper ion membrane transport|downregulation of copper cation transmembrane transport|downregulation of copper ion membrane transport|down-regulation of copper ion transmembrane transport Any process that stops, prevents or reduces the frequency, rate or extent of copper ion transmembrane transport. GO:0060130 thyroid-stimulating hormone-secreting cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060130 thyrotroph development|thyrotrope development|thyroid stimulating hormone secreting cell development|TSH-secreting cell development|beta-basophil development The process whose specific outcome is the progression of a thyroid-stimulating hormone-secreting cell over time, from its formation to the mature structure. A thyroid-stimulating hormone-secreting cell is a basophil cell of the anterior pituitary that produces thyroid stimulating hormone, thyrotrophin. GO:0060131 corticotropin hormone secreting cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060131 corticotrophin hormone secreting cell development|corticotrope development|corticotroph development|adrenocorticotrophic hormone secreting cell development|adrenocorticotropic hormone secreting cell development The process whose specific outcome is the progression of a corticotropic hormone secreting cell over time, from its formation to the mature structure. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin. GO:1902310 positive regulation of peptidyl-serine dephosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902310 up regulation of peptidyl-serine dephosphorylation|activation of peptidyl-serine dephosphorylation|up-regulation of peptidyl-serine dephosphorylation|upregulation of peptidyl-serine dephosphorylation Any process that activates or increases the frequency, rate or extent of peptidyl-serine dephosphorylation. GO:0060132 prolactin secreting cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060132 mammotroph development|mammotropic cell development|mammotrope development|epsilon-acidophil development|lactotroph development|lactotropic cell development|lactotrope development|mammotrophic cell development The process whose specific outcome is the progression of a prolactin secreting cell over time, from its formation to the mature structure. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin. GO:0035122 embryonic medial fin morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035122 embryonic unpaired fin morphogenesis The process, occurring in the embryo, by which the anatomical structures of the medial fin are generated and organized. Medial fins are unpaired fins of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming. GO:0060133 somatotropin secreting cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060133 somatotrophin secreting cell development|somatrophic cell development|growth hormone secreting cell development|somatotropic cell development|somatotroph development|somatotrope development The process whose specific outcome is the progression of a somatotropin secreting cell over time, from its formation to the mature structure. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin. GO:0060134 prepulse inhibition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060134 Wikipedia:Prepulse_inhibition PPI|pre-pulse inhibition The process in which a startle magnitude is reduced when the startling stimulus is preceded by a low-intensity prepulse. GO:0035123 embryonic dorsal fin morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035123 The process, occurring in the embryo, by which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of a fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins. GO:0035124 embryonic caudal fin morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035124 The process, occurring in the embryo, by which the anatomical structures of the caudal fin are generated and organized. The caudal fin is an unpaired medial fin mounted at the caudal end of the fish and is the main fin used for propulsion. GO:0060135 maternal process involved in female pregnancy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060135 A reproductive process occurring in the mother that allows an embryo or fetus to develop within it. GO:0035125 embryonic anal fin morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035125 The process, occurring in the embryo, by which the anatomical structures of the embryonic anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming. GO:0060136 embryonic process involved in female pregnancy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060136 A reproductive process occurring in the embryo or fetus that allows the embryo or fetus to develop within the mother. GO:0098709 glutathione import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098709 glutathione uptake|glutathione import into cell The directed movement of glutathione from outside of a cell, across the plasma membrane and into the cytosol. GO:0035126 post-embryonic genitalia morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035126 post-embryonic genital morphogenesis The process, occurring after embryonic development, by which the anatomical structures of the genitalia are generated and organized. GO:0060137 maternal process involved in parturition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060137 A reproductive process occurring in the mother that results in birth. GO:0060138 fetal process involved in parturition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060138 A reproductive process occurring in the embryo that results in birth. GO:0035127 post-embryonic limb morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035127 The process, occurring after embryonic development, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping. GO:0060139 positive regulation of apoptotic process by virus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060139 positive regulation of apoptosis by virus Any viral process that activates or increases the frequency, rate or extent of cell death by apoptotic process. GO:0035128 post-embryonic forelimb morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035128 The process, occurring after embryonic development, by which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an organism. GO:0098707 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0098707 GO:0098708 glucose import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098708 high affinity glucose import|glucose import into cell The directed movement of glucose from outside of a cell, across the plasma membrane and into the cytosol. GO:0035129 post-embryonic hindlimb morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035129 The process, occurring after embryonic development, by which the anatomical structures of the hindlimb are generated and organized. GO:0098705 copper ion import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098705 copper cation import into cell|high affinity copper ion transport|copper ion import into cell|high affinity copper transport|high-affinity copper ion transport The directed movement of copper ions from outside of a cell, across the plasma membrane and into the cytosol. GO:0098706 iron ion import across cell outer membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098706 high-affinity ferric iron transmembrane transport|ferric iron transmembrane transport|ferric iron import across cell outer membrane|high affinity ferric iron transport|ferric ion import into cell|ferric iron import into cell The directed movement of iron ions from outside of a cell, across the cell outer membrane and into the periplasmic space. GO:0098703 calcium ion import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098703 calcium ion import into cell|calcium ion uptake into cell The directed movement of calcium ions from outside of a cell, across the plasma membrane and into the cytosol. GO:0098704 carbohydrate import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098704 carbohydrate import into cell The directed movement of a carbohydrate from outside of a cell, across the plasma membrane and into the cytosol. GO:0098701 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0098701 GO:0098702 adenine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098702 adenine import into cell The directed movement of adenine from outside of a cell, across the plasma membrane and into the cytosol. GO:0035120 post-embryonic appendage morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035120 The process, occurring after embryonic development, by which the anatomical structures of an appendage are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch. GO:0035121 obsolete tail morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035121 tail morphogenesis OBSOLETE. The process in which the anatomical structures of the tail are generated and organized. The tail is the hindmost part of some animals. GO:0098700 neurotransmitter loading into synaptic vesicle biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098700 neurotransmitter uptake into synaptic vesicle|neurotransmitter import into synaptic vesicle|synaptic vesicle neurotransmitter loading The active transport of neurotransmitters into a synaptic vesicle. This import is fuelled by an electrochemical gradient across the vesicle membrane, established by the action of proton pumps. GO:1902328 bacterial-type DNA replication initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902328 DNA replication initiation involved in bacterial-type DNA replication|DNA-dependent DNA replication initiation involved in bacterial-type DNA replication|DNA endoreduplication initiation involved in bacterial-type DNA replication|DNA re-replication initiation involved in bacterial-type DNA replication Any DNA replication initiation that is involved in bacterial-type DNA replication. GO:1902329 bacterial-type DNA replication termination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902329 DNA replication termination involved in bacterial-type DNA replication Any DNA replication termination that is involved in bacterial-type DNA replication. GO:0035119 embryonic pelvic fin morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035119 The process, occurring in the embryo, by which the anatomical structures of the pelvic fin are generated and organized. The pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion. GO:1902326 positive regulation of chlorophyll biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902326 up-regulation of chlorophyll anabolism|up-regulation of chlorophyll synthesis|positive regulation of chlorophyll biosynthesis|up regulation of chlorophyll biosynthetic process|up regulation of chlorophyll biosynthesis|up-regulation of chlorophyll formation|upregulation of chlorophyll anabolism|upregulation of chlorophyll synthesis|upregulation of chlorophyll formation|upregulation of chlorophyll biosynthesis|upregulation of chlorophyll biosynthetic process|up regulation of chlorophyll anabolism|activation of chlorophyll anabolism|positive regulation of chlorophyll anabolism|up regulation of chlorophyll synthesis|activation of chlorophyll synthesis|positive regulation of chlorophyll synthesis|up regulation of chlorophyll formation|up-regulation of chlorophyll biosynthetic process|up-regulation of chlorophyll biosynthesis|activation of chlorophyll biosynthesis|activation of chlorophyll biosynthetic process|activation of chlorophyll formation|positive regulation of chlorophyll formation Any process that activates or increases the frequency, rate or extent of chlorophyll biosynthetic process. GO:1902327 bacterial-type DNA replication DNA ligation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902327 DNA ligation involved in bacterial-type DNA replication Any DNA ligation that is involved in bacterial-type DNA replication. GO:1902324 positive regulation of methyl-branched fatty acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902324 upregulation of methyl-branched fatty acid formation|upregulation of methyl-branched fatty acid biosynthetic process|upregulation of methyl-branched fatty acid biosynthesis|up-regulation of methyl-branched fatty acid anabolism|activation of methyl-branched fatty acid anabolism|up-regulation of methyl-branched fatty acid synthesis|activation of methyl-branched fatty acid synthesis|up-regulation of methyl-branched fatty acid formation|activation of methyl-branched fatty acid formation|up regulation of methyl-branched fatty acid biosynthetic process|up regulation of methyl-branched fatty acid biosynthesis|positive regulation of methyl-branched fatty acid biosynthesis|activation of methyl-branched fatty acid biosynthesis|positive regulation of methyl-branched fatty acid anabolism|activation of methyl-branched fatty acid biosynthetic process|up regulation of methyl-branched fatty acid anabolism|positive regulation of methyl-branched fatty acid synthesis|up regulation of methyl-branched fatty acid synthesis|positive regulation of methyl-branched fatty acid formation|up regulation of methyl-branched fatty acid formation|up-regulation of methyl-branched fatty acid biosynthesis|up-regulation of methyl-branched fatty acid biosynthetic process|upregulation of methyl-branched fatty acid anabolism|upregulation of methyl-branched fatty acid synthesis Any process that activates or increases the frequency, rate or extent of methyl-branched fatty acid biosynthetic process. GO:1902325 negative regulation of chlorophyll biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902325 inhibition of chlorophyll anabolism|down-regulation of chlorophyll formation|negative regulation of chlorophyll formation|down-regulation of chlorophyll biosynthetic process|down-regulation of chlorophyll biosynthesis|negative regulation of chlorophyll biosynthesis|inhibition of chlorophyll synthesis|inhibition of chlorophyll formation|downregulation of chlorophyll biosynthesis|downregulation of chlorophyll biosynthetic process|down regulation of chlorophyll anabolism|down regulation of chlorophyll biosynthesis|down regulation of chlorophyll biosynthetic process|inhibition of chlorophyll biosynthetic process|inhibition of chlorophyll biosynthesis|down regulation of chlorophyll synthesis|downregulation of chlorophyll anabolism|down regulation of chlorophyll formation|downregulation of chlorophyll synthesis|downregulation of chlorophyll formation|down-regulation of chlorophyll anabolism|negative regulation of chlorophyll anabolism|down-regulation of chlorophyll synthesis|negative regulation of chlorophyll synthesis Any process that stops, prevents or reduces the frequency, rate or extent of chlorophyll biosynthetic process. GO:1902322 regulation of methyl-branched fatty acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902322 regulation of methyl-branched fatty acid biosynthesis|regulation of methyl-branched fatty acid anabolism|regulation of methyl-branched fatty acid synthesis|regulation of methyl-branched fatty acid formation Any process that modulates the frequency, rate or extent of methyl-branched fatty acid biosynthetic process. GO:1902323 negative regulation of methyl-branched fatty acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902323 down regulation of methyl-branched fatty acid biosynthetic process|down regulation of methyl-branched fatty acid biosynthesis|downregulation of methyl-branched fatty acid biosynthesis|downregulation of methyl-branched fatty acid biosynthetic process|down-regulation of methyl-branched fatty acid anabolism|negative regulation of methyl-branched fatty acid anabolism|down-regulation of methyl-branched fatty acid synthesis|negative regulation of methyl-branched fatty acid synthesis|down-regulation of methyl-branched fatty acid formation|negative regulation of methyl-branched fatty acid formation|negative regulation of methyl-branched fatty acid biosynthesis|down-regulation of methyl-branched fatty acid biosynthesis|down-regulation of methyl-branched fatty acid biosynthetic process|downregulation of methyl-branched fatty acid anabolism|down regulation of methyl-branched fatty acid anabolism|downregulation of methyl-branched fatty acid synthesis|inhibition of methyl-branched fatty acid biosynthetic process|inhibition of methyl-branched fatty acid biosynthesis|inhibition of methyl-branched fatty acid anabolism|downregulation of methyl-branched fatty acid formation|down regulation of methyl-branched fatty acid synthesis|inhibition of methyl-branched fatty acid synthesis|down regulation of methyl-branched fatty acid formation|inhibition of methyl-branched fatty acid formation Any process that stops, prevents or reduces the frequency, rate or extent of methyl-branched fatty acid biosynthetic process. GO:1902320 nuclear DNA replication DNA duplex unwinding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902320 DNA duplex unwinding involved in nuclear cell cycle DNA replication|DNA duplex unwinding involved in DNA replication involved in S-phase|duplex DNA melting involved in DNA replication involved in S phase|DNA unwinding involved in DNA replication involved in S phase|DNA duplex unwinding involved in DNA replication during S phase|duplex DNA melting involved in DNA replication involved in S-phase|DNA unwinding involved in DNA replication involved in S-phase|DNA duplex unwinding involved in DNA replication involved in S phase|DNA unwinding involved in DNA replication during S phase|duplex DNA melting involved in DNA replication during S phase|DNA unwinding involved in nuclear cell cycle DNA replication Any DNA duplex unwinding that is involved in nuclear cell cycle DNA replication. GO:0060120 inner ear receptor cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060120 inner ear hair cell fate commitment The process in which a cell becomes committed to become an inner ear receptor cell. GO:1902321 methyl-branched fatty acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902321 methyl-branched fatty acid anabolism|methyl-branched fatty acid synthesis|methyl-branched fatty acid formation|methyl-branched fatty acid biosynthesis The chemical reactions and pathways resulting in the formation of methyl-branched fatty acid. GO:0060121 vestibular receptor cell stereocilium organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060121 vestibular receptor cell stereocilium organisation|vestibular hair cell stereocilium organization|vestibular receptor cell stereocilium organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of vestibular hair cells. GO:0060122 inner ear receptor cell stereocilium organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060122 inner ear receptor stereocilium organisation|inner ear receptor stereocilium organization and biogenesis|inner ear hair cell receptor stereocilium organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of inner ear receptor cells. GO:0035111 obsolete leg joint morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035111 leg joint morphogenesis OBSOLETE. The process in which the anatomical structures of a leg joint are generated and organized. The leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner. One example is the knee, which separates the leg tibia and femur. GO:0035112 genitalia morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035112 genital morphogenesis The process in which the anatomical structures of genitalia are generated and organized. The genitalia are the organs of reproduction or generation, external and internal. GO:1902330 synthesis of RNA primer involved in bacterial-type DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902330 replication priming involved in bacterial-type DNA replication Any synthesis of RNA primer that is involved in bacterial-type DNA replication. GO:0060123 regulation of growth hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060123 Any process that modulates the frequency, rate or extent of the regulated release of growth hormone from a cell. GO:0060124 positive regulation of growth hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060124 Any process that increases the frequency, rate or extent of the regulated release of growth hormone from a cell. GO:0035113 embryonic appendage morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035113 The process, occurring in the embryo, by which the anatomical structures of the appendage are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch. GO:0060125 negative regulation of growth hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060125 Any process that decreases or stops the frequency, rate or extent of the regulated release of growth hormone from a cell. GO:0035114 imaginal disc-derived appendage morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035114 The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism. GO:0060126 somatotropin secreting cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060126 somatotroph differentiation|somatotropic cell differentiation|somatotrope differentiation|somatotrophin secreting cell differentiation|somatrophic cell differentiation|growth hormone secreting cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a somatotropin secreting cell. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin. GO:0035115 embryonic forelimb morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035115 embryonic arm morphogenesis The process, occurring in the embryo, by which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human. GO:0035116 embryonic hindlimb morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035116 The process, occurring in the embryo, by which the anatomical structures of the hindlimbs are generated and organized. The hindlimbs are the posterior limbs of an animal. GO:0060127 prolactin secreting cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060127 mammotrophic cell differentiation|mammotroph differentiation|mammotropic cell differentiation|mammotrope differentiation|epsilon-acidophil differentiation|lactotroph differentiation|lactotropic cell differentiation|lactotrope differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a prolactin secreting cell. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin. GO:0060128 corticotropin hormone secreting cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060128 adrenocorticotrophic hormone secreting cell differentiation|adrenocorticotropic hormone secreting cell differentiation|corticotroph differentiation|corticotrophin hormone secreting cell differentiation|corticotrope differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a corticotropic hormone secreting cell. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin. GO:0098718 serine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098718 serine import into cell The directed movement of serine from outside of a cell, across the plasma membrane and into the cytosol. GO:0035117 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035117 GO:0098719 sodium ion import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098719 sodium ion import into cell|sodium ion import|sodium import The directed movement of sodium ions from outside of a cell, across the plasma membrane and into the cytosol. GO:0060129 thyroid-stimulating hormone-secreting cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060129 thyroid stimulating hormone secreting cell differentiation|TSH-secreting cell differentiation|beta-basophil differentiation|thyrotroph differentiation|thyrotrope differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a thyroid-stimulating hormone-secreting cell. A thyroid-stimulating hormone-secreting cell is a basophil cell of the anterior pituitary that produces thyroid-stimulating hormone, thyrotrophin. GO:0035118 embryonic pectoral fin morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035118 The process, occurring in the embryo, by which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion. GO:0098716 nickel cation import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098716 nickel cation import into cell The directed movement of nickel cations from outside of a cell, across the plasma membrane and into the cytosol. GO:0098717 pantothenate import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098717 pantothenate import|pantothenate import into cell The directed movement of pantothenate from outside of a cell, across the plasma membrane and into the cytosol. GO:0098714 malate import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098714 malate import into cell The directed movement of malate from outside of a cell, across the plasma membrane and into the cytosol. GO:0098715 malonic acid import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098715 malonic acid import into cell|malonate import into cell The directed movement of malonic acid from outside of a cell, across the plasma membrane and into the cytosol. GO:0098712 L-glutamate import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098712 L-glutamate(1-) import into cell|L-glutamate(1-) import across plasma membrane|L-glutamate import into cell The directed movement of L-glutamate from outside of a cell, across the plasma membrane and into the cytosol. GO:0098713 leucine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098713 L-leucine import into cell|leucine import into cell The directed movement of leucine from outside of a cell, across the plasma membrane and into the cytosol. GO:0098710 guanine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098710 guanine import into cell The directed movement of guanine from outside of a cell, across the plasma membrane and into the cytosol. GO:0098711 iron ion import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098711 ferrous iron import across plasma membrane|iron ion import into cell|iron import into cell|ferrous iron import into cell|ferrous ion import into cell The directed movement of iron ions from outside of a cell, across the plasma membrane and into the cytosol. GO:0035110 obsolete leg morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035110 leg morphogenesis OBSOLETE. The process in which the anatomical structures of a leg are generated and organized. A leg is a limb on which an animal walks and stands. GO:0098763 mitotic cell cycle phase biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0098763 One of the distinct periods or stages into which the mitotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events. GO:0098764 meiosis I cell cycle phase biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0098764 A meiotic cell cycle phase prior to a during which some part of meiosis I nuclear division or the proceeding cytokinesis occurs. GO:0098761 cellular response to interleukin-7 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098761 cellular response to IL-7 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-7 stimulus. GO:0098762 meiotic cell cycle phase biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0098762 One of the distinct periods or stages into which the meiotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events. GO:0098760 response to interleukin-7 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098760 response to IL-7 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-7 stimulus. GO:1902339 positive regulation of apoptotic process involved in morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902339 up regulation of apoptosis involved in morphogenesis|positive regulation of apoptosis involved in morphogenesis|up-regulation of morphogenetic apoptosis|up regulation of apoptotic process involved in morphogenesis|upregulation of apoptosis involved in development|activation of apoptotic process involved in morphogenesis|activation of apoptosis involved in morphogenesis|upregulation of morphogenetic apoptosis|up-regulation of apoptosis involved in morphogenesis|up regulation of apoptosis involved in development|positive regulation of apoptosis involved in development|up-regulation of apoptotic process involved in morphogenesis|upregulation of apoptosis involved in morphogenesis|activation of apoptosis involved in development|up regulation of morphogenetic apoptosis|positive regulation of morphogenetic apoptosis|upregulation of apoptotic process involved in morphogenesis|up-regulation of apoptosis involved in development|activation of morphogenetic apoptosis Any process that activates or increases the frequency, rate or extent of apoptotic process involved in morphogenesis. GO:1902337 regulation of apoptotic process involved in morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902337 regulation of apoptosis involved in development|regulation of morphogenetic apoptosis|regulation of apoptosis involved in morphogenesis Any process that modulates the frequency, rate or extent of apoptotic process involved in morphogenesis. GO:0035108 limb morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035108 limb bud morphogenesis The process in which the anatomical structures of a limb are generated and organized. A limb is a paired appendage of a tetrapod used for locomotion or grasping. GO:1902338 negative regulation of apoptotic process involved in morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902338 downregulation of apoptotic process involved in morphogenesis|inhibition of apoptosis involved in development|negative regulation of apoptosis involved in morphogenesis|down-regulation of apoptosis involved in morphogenesis|down regulation of apoptosis involved in development|inhibition of morphogenetic apoptosis|down-regulation of apoptotic process involved in morphogenesis|downregulation of apoptosis involved in development|down regulation of morphogenetic apoptosis|inhibition of apoptosis involved in morphogenesis|inhibition of apoptotic process involved in morphogenesis|downregulation of morphogenetic apoptosis|negative regulation of apoptosis involved in development|down-regulation of apoptosis involved in development|down regulation of apoptosis involved in morphogenesis|downregulation of apoptosis involved in morphogenesis|down-regulation of morphogenetic apoptosis|negative regulation of morphogenetic apoptosis|down regulation of apoptotic process involved in morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in morphogenesis. GO:0035109 obsolete imaginal disc-derived limb morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035109 imaginal disc-derived limb morphogenesis OBSOLETE. The process in which the anatomical structures of limbs that are derived from an imaginal disc are generated and organized. A limb is an appendage of an animal used for locomotion or grasping. An example of this process is found in Drosophila melanogaster. GO:1902335 obsolete positive chemotaxis involved in neuron migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902335 chemoattraction involved in neuron migration|positive chemotaxis involved in neuron migration|positive chemotaxis involved in neuron guidance|positive chemotaxis involved in neuron chemotaxis|positive chemotaxis involved in neuronal migration|chemoattraction involved in neuron chemotaxis|chemoattraction involved in neuron guidance|chemoattraction involved in neuronal migration OBSOLETE. Any positive chemotaxis that is involved in neuron migration. GO:1902336 positive regulation of retinal ganglion cell axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902336 up-regulation of retinal ganglion cell axon pathfinding|activation of retinal ganglion cell axon pathfinding|upregulation of retinal ganglion cell axon guidance|positive regulation of retinal ganglion cell axon pathfinding|up regulation of retinal ganglion cell axon pathfinding|up regulation of retinal ganglion cell axon guidance|activation of retinal ganglion cell axon guidance|upregulation of retinal ganglion cell axon pathfinding|up-regulation of retinal ganglion cell axon guidance Any process that activates or increases the frequency, rate or extent of retinal ganglion cell axon guidance. GO:0060150 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0060150 GO:0060151 peroxisome localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060151 peroxisome localisation Any process in which a peroxisome is transported to, and/or maintained in, a specific location. A peroxisome is a small membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules. GO:1902333 nuclear DNA replication DNA ligation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902333 DNA ligation involved in DNA replication during S phase|DNA ligation involved in DNA replication involved in S-phase|DNA ligation involved in nuclear cell cycle DNA replication|DNA ligation involved in DNA replication involved in S phase Any DNA ligation that is involved in nuclear cell cycle DNA replication. GO:1902334 fructose export from vacuole to cytoplasm biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902334 fructose transport from vacuole to cytoplasm The directed movement of fructose from vacuole to cytoplasm. GO:0060152 microtubule-based peroxisome localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060152 microtubule-based peroxisome localisation The microtubule-based process in which a peroxisome is transported to, and/or maintained in, a specific location. A peroxisome is a small membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules. GO:0060153 modulation by virus of host cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060153 VZ:1636 regulation of host cell cycle by virus|modulation of host cell cycle by virus|regulation by virus of host cell cycle|viral process regulating host cell cycle Any viral process that modulates the rate or extent of progression through the cell cycle. GO:1902331 obsolete DNA strand elongation involved in bacterial-type DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902331 OBSOLETE. Any DNA strand elongation that is involved in bacterial-type DNA replication. GO:1902332 bacterial-type DNA replication DNA duplex unwinding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902332 duplex DNA melting involved in bacterial-type DNA replication|DNA duplex unwinding involved in bacterial-type DNA replication|DNA unwinding involved in bacterial-type DNA replication Any DNA duplex unwinding that is involved in bacterial-type DNA replication. GO:0060154 obsolete cellular process regulating host cell cycle in response to virus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060154 OBSOLETE. Any cellular process that modulates the rate or extent of progression through the cell cycle in response to a virus. GO:1902340 negative regulation of chromosome condensation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902340 down regulation of nuclear chromosome condensation|downregulation of nuclear chromosome condensation|down regulation of chromosome condensation|downregulation of chromosome condensation|negative regulation of eukaryotic chromosome condensation|down-regulation of eukaryotic chromosome condensation|negative regulation of nuclear chromosome condensation|down-regulation of nuclear chromosome condensation|inhibition of nuclear chromosome condensation|down-regulation of chromosome condensation|downregulation of eukaryotic chromosome condensation|down regulation of eukaryotic chromosome condensation|inhibition of eukaryotic chromosome condensation|inhibition of chromosome condensation Any process that stops, prevents or reduces the frequency, rate or extent of chromosome condensation. GO:0060155 platelet dense granule organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060155 platelet dense granule organization and biogenesis|bull's eye body organization and biogenesis|platelet dense granule organisation|platelet dense body organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a platelet dense granule. A platelet dense granule is an electron-dense granule occurring in blood platelets that stores and secretes adenosine nucleotides and serotonin. They contain a highly condensed core consisting of serotonin, histamine, calcium, magnesium, ATP, ADP, pyrophosphate and membrane lysosomal proteins. GO:0035100 ecdysone binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035100 Interacting selectively and non-covalently with 20-hydroxyecdysone (ecdysone). Ecdysone is an ecdysteroid produced by the prothoracic glands of immature insects and the ovaries of adult females, which stimulates growth and molting. GO:1902341 xylitol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902341 The directed movement of a xylitol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Xylitol is a polyalcohol (pentane-1,2,3,4,5-pentol), produced by hydrogenation of xylose. GO:0035101 FACT complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035101 Facilitates chromatin transcription complex An abundant nuclear complex, which was originally identified in mammalian systems as a factor required for transcription elongation on chromatin templates. The FACT complex has been shown to destablilize the interaction between the H2A/H2B dimer and the H3/H4 tetramer of the nucleosome, thus reorganizing the structure of the nucleosome. In this way, the FACT complex may play a role in DNA replication and other processes that traverse the chromatin, as well as in transcription elongation. FACT is composed of two proteins that are evolutionarily conserved in all eukaryotes and homologous to mammalian Spt16 and SSRP1. In metazoans, the SSRP1 homolog contains an HMG domain; however in fungi and protists, it does not. For example, in S. cerevisiae the Pob3 protein is homologous to SSRP1, but lacks the HMG chromatin binding domain. Instead, the yFACT complex of Spt16p and Pob3p, binds to nucleosomes where multiple copies of the HMG-domain containing protein Nhp6p have already bound, but Nhp6p does not form a stable complex with the Spt16p/Pob3p heterodimer. GO:0060156 milk ejection reflex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060156 milk ejection A reflex that occurs in response to suckling, beginning with a nerve impulse from a receptor in the mammary gland and ending with the ejection of milk from the gland. Signaling never reaches a level of consciousness. GO:0035102 PRC1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035102 Polycomb repressive complex 1 A multiprotein complex that mediates monoubiquitination of lysine residues of histone H2A (lysine-118 in Drosophila or lysine-119 in mammals). The complex is required for stable long-term maintenance of transcriptionally repressed states and is involved in chromatin remodeling. GO:0060157 urinary bladder development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060157 The process whose specific outcome is the progression of the urinary bladder over time, from its formation to the mature structure. The urinary bladder is an elastic, muscular sac situated in the anterior part of the pelvic cavity in which urine collects before excretion. GO:0060158 phospholipase C-activating dopamine receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060158 activation of phospholipase C activity by dopamine receptor signalling pathway|activation of phospholipase C activity by dopamine receptor signaling pathway|dopamine receptor, phospholipase C activating pathway The series of molecular signals generated as a consequence of a dopamine receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG). GO:0035103 sterol regulatory element binding protein cleavage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035103 SREBP cleavage|sterol depletion response, SREBP cleavage|sterol regulatory element binding protein cleavage involved in ER-nuclear sterol response pathway The proteolytic release of a transcriptionally active sterol regulatory element binding protein (SREBP) from intracellular membranes, freeing it to move to the nucleus to upregulate transcription of target genes, in response to altered levels of one or more lipids. GO:0060159 regulation of dopamine receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060159 regulation of dopamine receptor signalling pathway Any process that modulates the frequency, rate or extent of a dopamine receptor signaling pathway activity. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands. GO:0035104 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035104 GO:0035105 obsolete sterol regulatory element binding protein import into nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035105 SREBP import into nucleus|SREBP nuclear translocation|sterol regulatory element binding protein nuclear translocation|SREBP import into nucleus involved in sterol depletion response|sterol depletion response, sterol regulatory element binding protein import into nucleus|sterol depletion response, SREBP import into nucleus|sterol depletion response, sterol regulatory element binding protein nuclear translocation|sterol regulatory element binding protein import into nucleus involved in sterol depletion response|sterol regulatory element binding protein nuclear translocation involved in sterol depletion response|sterol depletion response, SREBP nuclear translocation OBSOLETE. The transfer of a sterol regulatory element binding protein (SREBP) into the nucleus, across the nuclear membrane, in response to altered levels of one or more lipids. SREBPs are transcription factors that bind sterol regulatory elements (SREs), DNA motifs found in the promoters of target genes. GO:0035106 operant conditioning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035106 Wikipedia:Operant_conditioning instrumental conditioning Learning to anticipate future events on the basis of past experience with the consequences of one's own behavior. UBERON_CORE:indirectly_supplies indirectly_supplies biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/uberon/core#indirectly_supplies indirectly_supplies a indirectly_supplies s iff a has a branch and the branch supplies or indirectly supplies s GO:0035107 appendage morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035107 The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch. GO:0098769 TIMP family protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098769 Interacting selectively and non-covalently with any member of the Tissue inhibitors of metalloproteinases (TIMPs) family. TIMPs are endogenous protein regulators of the matrix metalloproteinase (MMPs) family. GO:0098767 obsolete meiosis II M phase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098767 OBSOLETE. M phase during meiosis II. GO:0098768 meiotic prometaphase I biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0098768 The meiotic cell cycle phase in eukaryotes between meiotic prophase I and meiotic metaphase I. During meiotic prometaphase I, the nuclear envelope breaks down and one kinetochore forms per chromosome. Chromosomes attach to spindle microtubules and begin to move towards the metaphase plate. GO:0098765 meiosis II cell cycle phase biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0098765 A meiotic cell cycle phase that occurs after meiosis I (the first meiotic nuclear division). GO:0098766 obsolete meiosis I M phase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098766 OBSOLETE. M phase during meiosis I. GO:0098774 curli biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098774 tafi|thin aggregative fimbrae A proteinaceous extracellular fiber, produced by an enteric bacterium, that is involved in surface and cell-cell contacts that promote community behavior and host colonization. GO:0098775 curli assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098775 The process of assembly of curli, extracellular fibers produced by enteric bacteria. This process occurs outside the cell, where it is coupled to secretion across the cell outer membrane via nucleation by elements of the transporter complex. GO:0098772 molecular function regulator biolink:MolecularActivity go-plus goslim_flybase_ribbon|gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0098772 A molecular function that modulates the activity of a gene product or complex. Examples include enzyme regulators and channel regulators. GO:0098773 skin epidermis development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098773 The process whose specific outcome is the progression of the skin epidermis over time, from its formation to the mature structure. GO:0098770 FBXO family protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098770 Interacting selectively and non-covalently with any member of the FBXO protein family. Members of this family have an F-box protein motif of approximately 50 amino acids that functions as a site of protein-protein interaction. GO:0098771 inorganic ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098771 Any process involved in the maintenance of an internal steady state of inorganic ions within an organism or cell. GO:1902348 cellular response to strigolactone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902348 cellular response to strigolactone analog GR24 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a strigolactone stimulus. GO:1902349 response to chloroquine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902349 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloroquine stimulus. GO:1902346 meiotic strand displacement involved in double-strand break repair via SDSA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902346 meiotic D-loop processing involved in double-strand break repair via synthesis-dependent strand annealing|meiotic displacement loop processing involved in double-strand break repair via synthesis-dependent strand annealing|meiotic D-loop processing involved in mitotic gene conversion|meiotic displacement loop processing involved in mitotic gene conversion|meiotic strand displacement involved in double-strand break repair via synthesis-dependent strand annealing|meiotic strand displacement involved in SDSA|meiotic displacement loop dissociation involved in double-strand break repair via synthesis-dependent strand annealing|meiotic D-loop dissociation involved in double-strand break repair via synthesis-dependent strand annealing|meiotic D-loop dissociation involved in mitotic gene conversion|meiotic displacement loop dissociation involved in mitotic gene conversion|meiotic strand displacement involved in mitotic gene conversion Any meiotic strand displacement that is involved in double-strand break repair via synthesis-dependent strand annealing (SDSA). GO:1902347 response to strigolactone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902347 response to strigolactone analog GR24 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a strigolactone stimulus. GO:1902344 negative regulation of maltose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902344 inhibition of maltose transport|down regulation of maltose transport|downregulation of maltose transport|down-regulation of maltose transport Any process that stops, prevents or reduces the frequency, rate or extent of maltose transport. GO:0060140 modulation by virus of syncytium formation via plasma membrane fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060140 The formation in a cell that has been targeted by a virus of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. GO:1902345 positive regulation of maltose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902345 up-regulation of maltose transport|upregulation of maltose transport|up regulation of maltose transport|activation of maltose transport Any process that activates or increases the frequency, rate or extent of maltose transport. GO:0060141 positive regulation of syncytium formation by virus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060141 syncytium formation induced by viral infection The process in which a virus increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. GO:0060142 regulation of syncytium formation by plasma membrane fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060142 Any process that modulates the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. GO:1902342 xylitol export biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902342 The directed movement of xylitol out of a cell or organelle. GO:0060143 positive regulation of syncytium formation by plasma membrane fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060143 Any process that increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. GO:1902343 regulation of maltose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902343 Any process that modulates the frequency, rate or extent of maltose transport. GO:0060144 obsolete host cellular process involved in virus induced gene silencing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060144 OBSOLETE. A cellular process occurring in the host cell that contributes to the process of posttranscriptional gene inactivation ('silencing') both of viral gene(s), and host gene(s) homologous to the viral genes. GO:1902351 response to imidacloprid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902351 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an imidacloprid stimulus. GO:1902352 obsolete negative regulation of filamentous growth of a population of unicellular organisms in response to starvation by negative regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902352 OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of filamentous growth of a population of unicellular organisms in response to starvation. GO:0060145 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0060145 GO:0060146 obsolete host gene silencing in virus induced gene silencing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060146 OBSOLETE. The posttranscriptional gene silencing of host genes that are homologous to viral genes after viral infection. GO:1902350 cellular response to chloroquine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902350 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloroquine stimulus. GO:0060147 regulation of posttranscriptional gene silencing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060147 Any process that modulates the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism. GO:0060148 positive regulation of posttranscriptional gene silencing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060148 Any process that increases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism. GO:0060149 negative regulation of posttranscriptional gene silencing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060149 Any process that decreases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism. GO:0098778 curli subunit secretion coupled to curli assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098778 extracellular nucleation-precipitation pathway The secretion of soluble curli subunits through the outer membrane, coupled to nucleation of curli fiber formation at the membrane surface. GO:0098779 positive regulation of mitophagy in response to mitochondrial depolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098779 positive regulation of macromitophagy in response to mitochondrial depolarization Any process that activates or increases the frequency, rate or extent of mitophagy in response to mitochondrial depolarization. GO:0098776 protein transport across the cell outer membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098776 The directed movement of proteins across the cell outer membrane. GO:0098777 protein secretion by the type VIII secretion system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098777 T8SS Protein secretion through the outer membrane via the mechanism used for the secretion of curli subunits. GO:0098741 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0098741 GO:0001796 regulation of type IIa hypersensitivity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001796 Any process that modulates the frequency, rate, or extent of type IIa hypersensitivity, a type of inflammatory response. GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098742 The attachment of one cell to another cell via adhesion molecules that are at least partially embedded in the plasma membrane. GO:0001797 negative regulation of type IIa hypersensitivity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001797 down-regulation of type IIa hypersensitivity|inhibition of type IIa hypersensitivity|down regulation of type IIa hypersensitivity|downregulation of type IIa hypersensitivity Any process that stops, prevents, or reduces the rate of type IIa hypersensitivity, a type of inflammatory response. GO:0001798 positive regulation of type IIa hypersensitivity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001798 up regulation of type IIa hypersensitivity|activation of type IIa hypersensitivity|stimulation of type IIa hypersensitivity|up-regulation of type IIa hypersensitivity|upregulation of type IIa hypersensitivity Any process that activates or increases the frequency, rate or extent of type IIa hypersensitivity, a type of inflammatory response. GO:0098740 obsolete multi organism cell adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098740 OBSOLETE. Cell adhesion that involves cells from multiple organisms or that is mediated by gene products from multiple organisms. GO:0001799 regulation of type IIb hypersensitivity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001799 Any process that modulates the frequency, rate, or extent of type IIb hypersensitivity, a type of inflammatory response. GO:0001792 polymeric immunoglobulin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001792 Combining with a J-chain-containing polymeric immunoglobulin of the IgA or IgM isotypes via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. CHEBI:144897 1-piperideinium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_144897 GO:0001793 IgM receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001793 Combining with an immunoglobulin of the IgM isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0001794 type IIa hypersensitivity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001794 An inflammatory response resulting in cell death mediated by activation of the classical complement pathway or induction of effector cell phagocytosis or cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell. GO:0001795 type IIb hypersensitivity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001795 type V hypersensitivity An inflammatory response resulting in cell death or dysfunction mediated by the direct binding of antibody to cellular receptors. GO:1902359 Notch signaling pathway involved in somitogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902359 Notch receptor signaling pathway involved in somitogenesis|Notch receptor signalling pathway involved in somitogenesis|Notch signalling pathway involved in formation of mesodermal clusters|N signaling pathway involved in formation of mesodermal clusters|Notch-receptor signaling pathway involved in formation of mesodermal clusters|Notch-receptor signalling pathway involved in formation of mesodermal clusters|N signalling pathway involved in somitogenesis|N signalling pathway involved in formation of mesodermal clusters|Notch signaling pathway involved in formation of mesodermal clusters|Notch-receptor signalling pathway involved in somitogenesis|Notch-receptor signaling pathway involved in somitogenesis|N signaling pathway involved in somitogenesis|Notch signalling pathway involved in somitogenesis|Notch receptor signalling pathway involved in formation of mesodermal clusters|Notch receptor signaling pathway involved in formation of mesodermal clusters Any Notch signaling pathway that is involved in somitogenesis. GO:0060170 ciliary membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0060170 cilium membrane|flagellar membrane|flagellum membrane|cilial membrane The portion of the plasma membrane surrounding a cilium. GO:0001790 polymeric immunoglobulin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001790 Interacting selectively and non-covalently with a J-chain-containing polymeric immunoglobulin of the IgA or IgM isotypes. GO:0060171 stereocilium membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0060171 The portion of the plasma membrane surrounding a stereocilium. GO:1902357 2-isopropylmalate(2-) transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902357 The process in which 2-isopropylmalate(2-) is transported across a membrane. GO:0001791 IgM binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001791 Interacting selectively and non-covalently with an immunoglobulin of the IgM isotype. GO:1902358 sulfate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902358 The directed movement of sulfate across a membrane. GO:0060172 astral microtubule depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060172 The removal of tubulin heterodimers from one or both ends of an astral microtubule. An astral microtubule is any of the spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell. GO:1902355 endothelial tube lumen extension involved in blood vessel lumen ensheathment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902355 Any endothelial tube lumen extension that is involved in blood vessel lumen ensheathment. GO:0060173 limb development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060173 Wikipedia:Limb_development limb bud development|paired limb/fin development The process whose specific outcome is the progression of a limb over time, from its formation to the mature structure. A limb is an appendage of an animal used for locomotion or grasping. Examples include legs, arms or some types of fin. GO:0060174 limb bud formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060174 limb formation|limbbud formation The process pertaining to the initial formation of a limb bud from unspecified parts. This process begins with the formation of a local condensation of mesenchyme cells within the prospective limb field, and ends when a limb bud is recognizable. GO:1902356 oxaloacetate(2-) transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902356 The directed movement of oxaloacetate(2-) across a membrane. GO:0060175 brain-derived neurotrophic factor-activated receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0060175 brain-derived neurotrophic factor receptor activity|BDNF receptor activity|BDNF-activated receptor activity Combining with a brain-derived neurotrophic factor and transmitting the signal across the plasma membrane to initiate a change in cell activity. GO:1902353 obsolete positive regulation of induction of conjugation with cellular fusion by negative regulation of transcription from RNA polymerase II promoter by pheromones biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902353 up regulation of induction of conjugation with cellular fusion by negative regulation of transcription from RNA polymerase II promoter by pheromones|up-regulation of induction of conjugation with cellular fusion by negative regulation of transcription from RNA polymerase II promoter by pheromones|upregulation of induction of conjugation with cellular fusion by negative regulation of transcription from RNA polymerase II promoter by pheromones OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter by pheromones that results in positive regulation of induction of conjugation with cellular fusion. GO:1902354 blood vessel endothelial cell delamination involved in blood vessel lumen ensheathment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902354 Any blood vessel endothelial cell delamination that is involved in blood vessel lumen ensheathment. GO:0060176 regulation of aggregation involved in sorocarp development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060176 Any process that modulates the frequency, rate or extent of aggregation during sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug. GO:1902362 melanocyte apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902362 melanophore apoptotic process|melanophore apoptosis|melanocyte apoptosis Any apoptotic process in a melanocyte, the main structural component of the epidermis. GO:0060177 regulation of angiotensin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060177 regulation of angiotensin metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving angiotensin. GO:1902363 regulation of protein localization to spindle pole body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902363 regulation of protein localisation to spindle pole body Any process that modulates the frequency, rate or extent of protein localization to spindle pole body. GO:0060178 regulation of exocyst localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060178 regulation of exocyst localisation Any process that modulates the localization of exocysts. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse. GO:0060179 male mating behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060179 The specific behavior of a male organism that is associated with reproduction. GO:1902360 conversion of ds siRNA to ss siRNA involved in chromatin silencing by small RNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902360 conversion of double-stranded small interfering RNA to single-stranded small interfering RNA involved in RNA interference-like chromatin silencing|conversion of ds siRNA to ss siRNA involved in RNA-mediated transcriptional silencing|conversion of ds siRNA to ss siRNA involved in RNAi-directed chromatin silencing|conversion of double-stranded small interfering RNA to single-stranded small interfering RNA involved in RNAi-like chromatin silencing|conversion of double-stranded small interfering RNA to single-stranded small interfering RNA involved in chromatin silencing by small RNA|conversion of ds siRNA to ss siRNA involved in RNA interference-like chromatin silencing|conversion of double-stranded small interfering RNA to single-stranded small interfering RNA involved in small RNA-mediated heterochromatic silencing|conversion of double-stranded small interfering RNA to single-stranded small interfering RNA involved in RNA-mediated chromatin silencing|conversion of ds siRNA to ss siRNA involved in RNAi-like chromatin silencing|conversion of double-stranded small interfering RNA to single-stranded small interfering RNA involved in RNAi-directed chromatin silencing|conversion of ds siRNA to ss siRNA involved in small RNA-mediated heterochromatic silencing|conversion of double-stranded small interfering RNA to single-stranded small interfering RNA involved in RNA-mediated transcriptional silencing|conversion of ds siRNA to ss siRNA involved in RNA-mediated chromatin silencing Any conversion of ds siRNA to ss siRNA that is involved in chromatin silencing by small RNA. GO:1902361 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902361 GO:0098749 cerebellar neuron development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098749 The process whose specific outcome is the progression of a cerebellar neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. GO:0098747 slow, calcium ion-dependent exocytosis of neurotransmitter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098747 The slow, second phase of calcium ion-induced neurotransmitter release, via exocytosis, into the synaptic cleft. This depends on high affinity calcium sensors and decays slowly, typically with a decay constant of over 100ms. The underlying molecular mechanisms of this process are distinct from those of the earlier, fast phase of release. GO:0098748 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0098748 GO:0098745 Dcp1-Dcp2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098745 A protein complex consisting of a Dcp1 regulatory subunit and a Dcp2 catalytic subunit that has mRNA cap binding activity and is involved in decapping of nuclear-transcribed mRNA. GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098746 synchronous, calcium ion-dependent exocytosis of neurotransmitter The fast, initial phase of calcium ion-induced neurotransmitter release, via exocytosis, into the synaptic cleft. This depends on low affinity calcium sensors and typically begins a fraction of a millisecond after Ca2+ influx, and decays rapidly (1-10ms) with a decay constant of around 5-10ms. The underlying molecular mechanisms of this process are distinct from those of the later, slow phase of release. GO:0098743 cell aggregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098743 The clustering together and adhesion of initially separate cells to form an aggregate. Examples include the clustering of unicellular organisms or blood cells in suspension and the condensation of mesenchymal cells during cartilage formation. GO:0098744 1-phosphatidylinositol 4-kinase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098744 Binds to and increases the activity of 1-phosphatidylinositol 4-kinase. GO:0098752 integral component of the cytoplasmic side of the plasma membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098752 The component of the plasma membrane consisting of the gene products that penetrate only the cytoplasmic side of the membrane. GO:0098753 anchored component of the cytoplasmic side of the plasma membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098753 The component of the plasma membrane consisting of gene products and protein complexes with covalently attached hydrophobic anchors products that penetrate only the cytoplasmic side of the membrane. GO:0098750 FYXD domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098750 Interacting selectively and non-covalently with a FXYD domain. GO:0098751 bone cell development biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0098751 The process whose specific outcome is the progression of a bone cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. GO:2001303 lipoxin A4 biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001303 lipoxin A4 biosynthesis|LXA4 anabolism|LXA4 synthesis|LXA4 formation|LXA4 biosynthetic process|LXA4 biosynthesis|lipoxin A4 anabolism|lipoxin A4 synthesis|lipoxin A4 formation The chemical reactions and pathways resulting in the formation of lipoxin A4. Lipoxin A4 is a C20 hydroxy fatty acid having (5S)-, (6R)- and (15S)-hydroxy groups as well as (7E)- (9E)-, (11Z)- and (13E)-double bonds. GO:2001304 lipoxin B4 metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001304 lipoxin B4 metabolism|LXB4 metabolism|LXB4 metabolic process The chemical reactions and pathways involving lipoxin B4. Lipoxin B4 is a C20 hydroxy fatty acid having (5S)-, (14R)- and (15S)-hydroxy groups as well as (6E)- (8Z)-, (10E)- and (12E)-double bonds. GO:0060160 negative regulation of dopamine receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060160 negative regulation of dopamine receptor signalling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of dopamine receptor protein signaling pathway activity. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands. GO:2001305 xanthone-containing compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001305 xanthone metabolism|xanthone-containing compound metabolism|xanthones metabolic process|xanthones metabolism The chemical reactions and pathways involving a xanthone-containing compound. GO:1902368 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902368 GO:1902369 negative regulation of RNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902369 negative regulation of RNA breakdown|negative regulation of RNA catabolism|down-regulation of RNA breakdown|down-regulation of RNA catabolism|inhibition of RNA degradation|down-regulation of RNA catabolic process|inhibition of RNA breakdown|downregulation of RNA catabolism|inhibition of RNA catabolic process|down regulation of RNA catabolism|inhibition of RNA catabolism|down regulation of RNA degradation|downregulation of RNA degradation|down regulation of RNA breakdown|down regulation of RNA catabolic process|downregulation of RNA breakdown|down-regulation of RNA degradation|negative regulation of RNA degradation|downregulation of RNA catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of RNA catabolic process. GO:0060161 positive regulation of dopamine receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060161 positive regulation of dopamine receptor signalling pathway Any process that activates or increases the frequency, rate or extent of the dopamine receptor protein signaling pathway. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands. GO:2001306 lipoxin B4 biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001306 lipoxin B4 biosynthesis|LXB4 anabolism|LXB4 synthesis|LXB4 formation|LXB4 biosynthesis|LXB4 biosynthetic process|lipoxin B4 anabolism|lipoxin B4 synthesis|lipoxin B4 formation The chemical reactions and pathways resulting in the formation of lipoxin B4. Lipoxin B4 is a C20 hydroxy fatty acid having (5S)-, (14R)- and (15S)-hydroxy groups as well as (6E)- (8Z)-, (10E)- and (12E)-double bonds. GO:1902366 regulation of Notch signaling pathway involved in somitogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902366 regulation of N signaling pathway involved in formation of mesodermal clusters|regulation of Notch receptor signalling pathway involved in somitogenesis|regulation of Notch signalling pathway involved in formation of mesodermal clusters|regulation of Notch-receptor signalling pathway involved in formation of mesodermal clusters|regulation of N signalling pathway involved in somitogenesis|regulation of Notch-receptor signaling pathway involved in formation of mesodermal clusters|regulation of Notch signaling pathway involved in formation of mesodermal clusters|regulation of Notch-receptor signaling pathway involved in somitogenesis|regulation of N signalling pathway involved in formation of mesodermal clusters|regulation of Notch-receptor signalling pathway involved in somitogenesis|regulation of Notch signalling pathway involved in somitogenesis|regulation of Notch receptor signalling pathway involved in formation of mesodermal clusters|regulation of N signaling pathway involved in somitogenesis|regulation of Notch receptor signaling pathway involved in somitogenesis|regulation of Notch receptor signaling pathway involved in formation of mesodermal clusters Any process that modulates the frequency, rate or extent of Notch signaling pathway involved in somitogenesis. GO:2001307 xanthone-containing compound biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001307 xanthones anabolism|xanthones synthesis|xanthones formation|xanthone-containing compound anabolism|xanthone biosynthesis|xanthone biosynthetic process|xanthone-containing compound synthesis|xanthone-containing compound biosynthesis|xanthone-containing compound formation|xanthones biosynthesis|xanthones biosynthetic process The chemical reactions and pathways resulting in the formation of a xanthone-containing compound. GO:0060162 negative regulation of phospholipase C-activating dopamine receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060162 negative regulation of dopamine receptor, phospholipase C activating pathway|negative regulation of phospholipase C-activating dopamine receptor signalling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the dopamine receptor, phospholipase C activating pathway. GO:1902367 negative regulation of Notch signaling pathway involved in somitogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902367 downregulation of N signaling pathway involved in formation of mesodermal clusters|downregulation of Notch receptor signaling pathway involved in formation of mesodermal clusters|negative regulation of Notch signaling pathway involved in formation of mesodermal clusters|down-regulation of Notch signaling pathway involved in formation of mesodermal clusters|inhibition of N signalling pathway involved in formation of mesodermal clusters|negative regulation of N signaling pathway involved in somitogenesis|down-regulation of N signaling pathway involved in somitogenesis|negative regulation of Notch-receptor signaling pathway involved in somitogenesis|down-regulation of Notch-receptor signaling pathway involved in somitogenesis|down regulation of Notch receptor signalling pathway involved in somitogenesis|inhibition of Notch-receptor signalling pathway involved in somitogenesis|down regulation of Notch signalling pathway involved in formation of mesodermal clusters|down regulation of N signaling pathway involved in formation of mesodermal clusters|downregulation of Notch-receptor signalling pathway involved in formation of mesodermal clusters|inhibition of N signaling pathway involved in formation of mesodermal clusters|downregulation of N signalling pathway involved in somitogenesis|downregulation of Notch receptor signalling pathway involved in somitogenesis|downregulation of Notch signalling pathway involved in formation of mesodermal clusters|negative regulation of Notch signalling pathway involved in somitogenesis|down-regulation of Notch signalling pathway involved in somitogenesis|negative regulation of Notch receptor signaling pathway involved in formation of mesodermal clusters|down-regulation of Notch receptor signalling pathway involved in formation of mesodermal clusters|down regulation of Notch-receptor signalling pathway involved in formation of mesodermal clusters|negative regulation of Notch receptor signalling pathway involved in formation of mesodermal clusters|inhibition of N signaling pathway involved in somitogenesis|down-regulation of Notch receptor signaling pathway involved in formation of mesodermal clusters|down regulation of Notch-receptor signaling pathway involved in formation of mesodermal clusters|downregulation of Notch signaling pathway involved in formation of mesodermal clusters|down regulation of Notch signaling pathway involved in somitogenesis|down regulation of N signalling pathway involved in somitogenesis|inhibition of Notch-receptor signalling pathway involved in formation of mesodermal clusters|downregulation of Notch-receptor signaling pathway involved in somitogenesis|inhibition of N signalling pathway involved in somitogenesis|downregulation of Notch-receptor signaling pathway involved in formation of mesodermal clusters|down regulation of N signalling pathway involved in formation of mesodermal clusters|down regulation of Notch signaling pathway involved in formation of mesodermal clusters|downregulation of Notch signaling pathway involved in somitogenesis|down regulation of Notch-receptor signalling pathway involved in somitogenesis|down regulation of Notch-receptor signaling pathway involved in somitogenesis|down-regulation of Notch receptor signalling pathway involved in somitogenesis|inhibition of Notch receptor signaling pathway involved in formation of mesodermal clusters|negative regulation of Notch receptor signalling pathway involved in somitogenesis|negative regulation of Notch receptor signaling pathway involved in somitogenesis|inhibition of Notch signaling pathway involved in formation of mesodermal clusters|down-regulation of Notch receptor signaling pathway involved in somitogenesis|downregulation of Notch signalling pathway involved in somitogenesis|negative regulation of Notch signalling pathway involved in formation of mesodermal clusters|down-regulation of Notch signalling pathway involved in formation of mesodermal clusters|downregulation of N signalling pathway involved in formation of mesodermal clusters|downregulation of Notch receptor signalling pathway involved in formation of mesodermal clusters|inhibition of Notch-receptor signaling pathway involved in somitogenesis|downregulation of Notch-receptor signalling pathway involved in somitogenesis|down regulation of Notch signalling pathway involved in somitogenesis|down regulation of N signaling pathway involved in somitogenesis|down regulation of Notch receptor signalling pathway involved in formation of mesodermal clusters|negative regulation of Notch-receptor signaling pathway involved in formation of mesodermal clusters|down-regulation of Notch-receptor signaling pathway involved in formation of mesodermal clusters|negative regulation of N signaling pathway involved in formation of mesodermal clusters|down-regulation of N signaling pathway involved in formation of mesodermal clusters|inhibition of Notch signalling pathway involved in somitogenesis|inhibition of Notch receptor signalling pathway involved in somitogenesis|inhibition of Notch receptor signalling pathway involved in formation of mesodermal clusters|inhibition of Notch signalling pathway involved in formation of mesodermal clusters|down-regulation of Notch signaling pathway involved in somitogenesis|downregulation of N signaling pathway involved in somitogenesis|downregulation of Notch receptor signaling pathway involved in somitogenesis|down-regulation of N signalling pathway involved in formation of mesodermal clusters|negative regulation of N signalling pathway involved in formation of mesodermal clusters|down regulation of Notch receptor signaling pathway involved in formation of mesodermal clusters|down-regulation of Notch-receptor signalling pathway involved in formation of mesodermal clusters|negative regulation of Notch-receptor signalling pathway involved in formation of mesodermal clusters|down-regulation of Notch-receptor signalling pathway involved in somitogenesis|inhibition of Notch-receptor signaling pathway involved in formation of mesodermal clusters|negative regulation of Notch-receptor signalling pathway involved in somitogenesis|down regulation of Notch receptor signaling pathway involved in somitogenesis|down-regulation of N signalling pathway involved in somitogenesis|negative regulation of N signalling pathway involved in somitogenesis|inhibition of Notch receptor signaling pathway involved in somitogenesis|inhibition of Notch signaling pathway involved in somitogenesis Any process that stops, prevents or reduces the frequency, rate or extent of Notch signaling pathway involved in somitogenesis. GO:0060163 subpallium neuron fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060163 subpallium neuronal precursor fate commitment The process in which in the subpallium, the developmental fate of a cell becomes restricted such that it will develop into a neuron. The subpallium is the base region of the telencephalon. GO:2001308 gliotoxin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001308 gliotoxin metabolism The chemical reactions and pathways involving the epipolythiodioxopiperazine gliotoxin, a poisonous substance produced by some species of fungi. GO:2001309 gliotoxin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001309 gliotoxin degradation|gliotoxin catabolism|gliotoxin breakdown The chemical reactions and pathways resulting in the breakdown of the epipolythiodioxopiperazine gliotoxin, a poisonous substance produced by some species of fungi. GO:1902364 negative regulation of protein localization to spindle pole body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902364 inhibition of protein localization to spindle pole body|negative regulation of protein localisation to spindle pole body|down-regulation of protein localisation to spindle pole body|inhibition of protein localisation to spindle pole body|down regulation of protein localization to spindle pole body|downregulation of protein localization to spindle pole body|down regulation of protein localisation to spindle pole body|downregulation of protein localisation to spindle pole body|down-regulation of protein localization to spindle pole body Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to spindle pole body. GO:0060164 regulation of timing of neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060164 The process controlling the activation and/or rate at which a relatively unspecialized cell acquires features of a neuron. GO:1902365 positive regulation of protein localization to spindle pole body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902365 up-regulation of protein localization to spindle pole body|up-regulation of protein localisation to spindle pole body|upregulation of protein localization to spindle pole body|upregulation of protein localisation to spindle pole body|up regulation of protein localization to spindle pole body|activation of protein localization to spindle pole body|up regulation of protein localisation to spindle pole body|activation of protein localisation to spindle pole body|positive regulation of protein localisation to spindle pole body Any process that activates or increases the frequency, rate or extent of protein localization to spindle pole body. GO:0060165 regulation of timing of subpallium neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060165 The process controlling the timing and/or rate at which a relatively unspecialized cell in the subpallium acquires features of a neuron. The subpallium is the base region of the telencephalon. GO:1902373 negative regulation of mRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902373 downregulation of mRNA degradation|down-regulation of mRNA catabolic process|inhibition of mRNA catabolism|down regulation of mRNA degradation|downregulation of mRNA breakdown|inhibition of mRNA degradation|negative regulation of mRNA decay|down-regulation of mRNA decay|down regulation of mRNA breakdown|downregulation of mRNA catabolic process|inhibition of mRNA breakdown|down regulation of mRNA catabolism|down regulation of mRNA catabolic process|inhibition of mRNA catabolic process|downregulation of mRNA catabolism|downregulation of mRNA decay|down regulation of mRNA decay|negative regulation of mRNA degradation|down-regulation of mRNA degradation|negative regulation of mRNA catabolism|down-regulation of mRNA catabolism|down-regulation of mRNA breakdown|negative regulation of mRNA breakdown|inhibition of mRNA decay Any process that stops, prevents or reduces the frequency, rate or extent of mRNA catabolic process. GO:0060166 olfactory pit development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060166 The biological process whose specific outcome is the progression of the olfactory pit from an initial condition to its mature state. This process begins with the formation of the olfactory pit, which is an indentation of the olfactory placode, and ends when the pits hollows out to form the nasopharynx. GO:0060167 regulation of adenosine receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060167 regulation of adenosine receptor signalling pathway Any process that modulates the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands. GO:1902374 regulation of rRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902374 regulation of rRNA degradation|regulation of rRNA catabolism|regulation of rRNA breakdown Any process that modulates the frequency, rate or extent of rRNA catabolic process. GO:1902371 negative regulation of tRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902371 down-regulation of tRNA breakdown|negative regulation of tRNA breakdown|down regulation of tRNA catabolism|downregulation of tRNA degradation|down-regulation of tRNA catabolic process|downregulation of tRNA catabolism|down regulation of tRNA degradation|downregulation of tRNA breakdown|inhibition of tRNA degradation|downregulation of tRNA catabolic process|down regulation of tRNA breakdown|inhibition of tRNA breakdown|down-regulation of tRNA catabolism|negative regulation of tRNA catabolism|down regulation of tRNA catabolic process|inhibition of tRNA catabolic process|inhibition of tRNA catabolism|negative regulation of tRNA degradation|down-regulation of tRNA degradation Any process that stops, prevents or reduces the frequency, rate or extent of tRNA catabolic process. GO:0060168 positive regulation of adenosine receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060168 positive regulation of adenosine receptor signalling pathway Any process that activates or increases the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands. GO:1902372 positive regulation of tRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902372 activation of tRNA catabolic process|up-regulation of tRNA catabolic process|positive regulation of tRNA degradation|upregulation of tRNA catabolism|up regulation of tRNA degradation|positive regulation of tRNA breakdown|up regulation of tRNA breakdown|up regulation of tRNA catabolism|up regulation of tRNA catabolic process|activation of tRNA catabolism|upregulation of tRNA degradation|positive regulation of tRNA catabolism|upregulation of tRNA breakdown|up-regulation of tRNA degradation|upregulation of tRNA catabolic process|activation of tRNA degradation|up-regulation of tRNA catabolism|activation of tRNA breakdown|up-regulation of tRNA breakdown Any process that activates or increases the frequency, rate or extent of tRNA catabolic process. GO:0060169 negative regulation of adenosine receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060169 negative regulation of adenosine receptor signalling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands. GO:1902370 regulation of tRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902370 regulation of tRNA catabolism|regulation of tRNA degradation|regulation of tRNA breakdown Any process that modulates the frequency, rate or extent of tRNA catabolic process. GO:2001300 lipoxin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001300 lipoxin metabolism The chemical reactions and pathways involving a lipoxin. A lipoxin is a non-classic eicosanoid and signalling molecule that has four conjugated double bonds and is derived from arachidonic acid. GO:2001301 lipoxin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001301 lipoxin anabolism|lipoxin synthesis|lipoxin formation|lipoxin biosynthesis The chemical reactions and pathways resulting in the formation of a lipoxin. A lipoxin is a non-classic eicosanoid and signalling molecule that has four conjugated double bonds and is derived from arachidonic acid. GO:2001302 lipoxin A4 metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001302 lipoxin A4 metabolism|LXA4 metabolism|LXA4 metabolic process The chemical reactions and pathways involving lipoxin A4. Lipoxin A4 is a C20 hydroxy fatty acid having (5S)-, (6R)- and (15S)-hydroxy groups as well as (7E)- (9E)-, (11Z)- and (13E)-double bonds. GO:0098758 response to interleukin-8 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098758 response to IL-8 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-8 stimulus. GO:0098759 cellular response to interleukin-8 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098759 cellular response to IL-8 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-8 stimulus. GO:0098756 response to interleukin-21 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098756 response to IL-21 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-21 stimulus. GO:0098757 cellular response to interleukin-21 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098757 cellular response to IL-21 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-21 stimulus. GO:0098754 detoxification biolink:BiologicalProcess go-plus goslim_pombe http://purl.obolibrary.org/obo/GO_0098754 Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance. GO:0098755 maintenance of seed dormancy by absisic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098755 The process by which seed dormancy is maintained by the presence of absisic acid. GO:0050701 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050701 GO:0050702 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050702 GO:0050700 CARD domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050700 Interacting selectively and non-covalently with a CARD (N-terminal caspase recruitment) domain, a protein-protein interaction domain that belongs to the death domain-fold superfamily. These protein molecule families are similar in structure with each consisting of six or seven anti-parallel alpha-helices that form highly specific homophilic interactions between signaling partners. CARD exists in the N-terminal prodomains of several caspases and in apoptosis-regulatory proteins and mediates the assembly of CARD-containing proteins that participate in activation or suppression of CARD carrying members of the caspase family. GO:0050705 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050705 GO:0050706 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050706 GO:0050703 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050703 CHEBI:62480 spheroiden-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62480 CHEBI:62481 (3E)-3,4-didehydrorhodopin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62481 GO:0050704 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050704 GO:0050709 negative regulation of protein secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050709 down-regulation of protein secretion|inhibition of protein secretion|down regulation of protein secretion|downregulation of protein secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell. GO:0050707 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050707 GO:0050708 regulation of protein secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050708 Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell. CHEBI:86457 2-hydroxybenzoyl-AMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86457 CHEBI:86458 2-hydroxybenzoyl-AMP(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86458 CHEBI:86459 (R)-lipoyl-GMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86459 CHEBI:62488 signalling molecule biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62488 GO:0050712 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050712 CHEBI:62490 sphingomyelin d18:1(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62490 GO:0050713 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050713 GO:0050710 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050710 GO:0050711 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050711 GO:0050716 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050716 GO:0050717 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050717 GO:0050714 positive regulation of protein secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050714 upregulation of protein secretion|up regulation of protein secretion|activation of protein secretion|stimulation of protein secretion|up-regulation of protein secretion Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell. GO:0050715 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050715 CHEBI:86441 (2E)-pentenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86441 CHEBI:62497 7-(3-methylbut-2-enyl)-L-tryptophan zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62497 CHEBI:62495 D-glucosylsphingosine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62495 GO:0050718 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050718 GO:0050719 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050719 CHEBI:62499 methyl-branched fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62499 GO:0050720 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050720 GO:0050723 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050723 GO:0050724 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050724 GO:0050721 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050721 GO:0050722 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050722 GO:0050727 regulation of inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050727 Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. GO:0050728 negative regulation of inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050728 down-regulation of inflammatory response|inhibition of inflammatory response|anti-inflammatory response|down regulation of inflammatory response|downregulation of inflammatory response Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response. GO:0050725 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050725 GO:0050726 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050726 GO:0050729 positive regulation of inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050729 up regulation of inflammatory response|activation of inflammatory response|stimulation of inflammatory response|up-regulation of inflammatory response|upregulation of inflammatory response Any process that activates or increases the frequency, rate or extent of the inflammatory response. CHEBI:86478 antibiotic antifungal agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86478 GO:0050730 regulation of peptidyl-tyrosine phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050730 Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine. GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050731 up regulation of peptidyl-tyrosine phosphorylation|activation of peptidyl-tyrosine phosphorylation|stimulation of peptidyl-tyrosine phosphorylation|up-regulation of peptidyl-tyrosine phosphorylation|upregulation of peptidyl-tyrosine phosphorylation Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine. GO:0050734 hydroxycinnamoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050734 Catalysis of the transfer of a hydroxycinnamoyl group to an acceptor molecule. GO:0050735 N-malonyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050735 Catalysis of the transfer of a malonyl group to a nitrogen atom on the acceptor molecule. GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050732 down-regulation of peptidyl-tyrosine phosphorylation|inhibition of peptidyl-tyrosine phosphorylation|down regulation of peptidyl-tyrosine phosphorylation|downregulation of peptidyl-tyrosine phosphorylation Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine. GO:0050733 RS domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050733 Interacting selectively and non-covalently with an RS domain of a protein; RS domains are usually highly phosphorylated and characterized by the presence of arginine (R)/serine (S) dipeptides. The RS domain promotes protein-protein interactions and directs subcellular localization and, in certain situations, nucleocytoplasmic shuttling of individual SR proteins. They also play a role in splicing. GO:0050738 fructosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050738 Catalysis of the transfer of a fructosyl group to an acceptor molecule, typically another carbohydrate or a lipid. CHEBI:86460 (R)-lipoyl-GMP(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86460 GO:0050739 peptide cross-linking via S-[5'-(L-tryptoph-6'-yl)-L-tyrosin-3'-yl]-L-methionin-S-ium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050739 RESID:AA0348 The cross-linking of a tyrosine residue to a tryptophan residue and a methionine residue to form S-[5'-(L-tryptoph-6'-yl)-L-tyrosin-3'-yl]-L-methionin-S-ium. GO:0050736 O-malonyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050736 Catalysis of the transfer of a malonyl group to an oxygen atom on the acceptor molecule. CHEBI:86462 O-(S-2-hydroxybenzoylpantetheine-4'-phosphoryl)-L-serine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86462 GO:0050737 O-hydroxycinnamoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050737 Catalysis of the transfer of a hydroxycinnamoyl group to an oxygen atom on the acceptor molecule. CHEBI:86464 O-(S-2-hydroxybenzoylpantetheine-4'-phosphoryl)-L-serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86464 GO:0035199 salt aversion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035199 behavioral response to salt The specific avoidance actions or reactions of an organism in response to the perception of salt. CHEBI:86468 dimethylarginine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86468 CHEBI:86469 peptidoglycosaminoglycan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86469 GO:0035191 nuclear axial expansion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035191 nuclear distribution along anterior-posterior axis|nucleus distribution along anterior-posterior axis The stepwise asymmetric spreading out of nuclei internally along the anterior-posterior axis of the developing insect embryo during mitotic cycles 4 to 6. This movement leads to the distribution of nuclei in a hollow ellipsoid underlying the cortex. GO:0035192 nuclear cortical migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035192 The symmetric outward movement of the syncytial nuclei from their positions in the ellipsoid toward the periphery of the embryo, during mitotic cycles 8 and 9. This movement results in the placement of nuclei in a uniform monolayer at the cortex of the developing embryo. GO:0035193 larval central nervous system remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035193 central nervous system metamorphosis|CNS metamorphosis Reorganization of the pre-existing, functional larval central nervous system into one that can serve the novel behavioral needs of the adult. An example of this process is found in Drosophila melanogaster. GO:0035194 post-transcriptional gene silencing by RNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035194 RNA-mediated posttranscriptional gene silencing|sense-PTGS|posttranscriptional gene silencing by RNA Any process of posttranscriptional gene inactivation (silencing) mediated by small RNA molecules that may trigger RNA (often mRNA) degradation or negatively regulate mRNA translation. GO:0035195 gene silencing by miRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035195 microRNA-mediated gene silencing|gene silencing by microRNA|miRNA-mediated gene silencing Downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: endolytic cleavage of the RNA (often mRNA) or mRNA translational repression, usually accompanied by poly-A tail shortening and subsequent degradation of the mRNA. GO:0035196 production of miRNAs involved in gene silencing by miRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035196 microRNA metabolic process|microRNA biogenesis|miRNA biogenesis|miRNA-mediated gene silencing, production of miRNAs|miRNA processing|gene silencing by miRNA, production of miRNAs|microRNA processing|microRNA biosynthesis|microRNA biosynthetic process|microRNA-mediated gene silencing, production of microRNAs|microRNA metabolism|production of microRNAs involved in gene silencing by microRNA Cleavage of stem-loop RNA precursors into microRNAs (miRNAs), a class of small RNAs that primarily silence genes by blocking the translation of mRNA transcripts into protein, or by increasing the degradation of non-protein-coding RNA transcripts. GO:0035197 siRNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035197 small interfering RNA binding Interacting selectively and non-covalently with a small interfering RNA, a 21-23 nucleotide RNA that is processed from double stranded RNA (dsRNA) by an RNAse enzyme. GO:0035198 miRNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035198 microRNA binding Interacting selectively and non-covalently with a microRNA, a 21-23 nucleotide RNA that is processed from a stem-loop RNA precursor (pre-miRNA) that is encoded within plant and animal genomes. GO:0050741 protein-FMN linkage via O3-riboflavin phosphoryl-L-serine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050741 RESID:AA0350 The formation of a protein-FMN linkage via O3-riboflavin phosphoryl-L-serine. GO:0050742 protein-FMN linkage via S-(4a-FMN)-L-cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050742 RESID:AA0351 The formation of a protein-FMN linkage via S-(4a-FMN)-L-cysteine. GO:0050740 protein-FMN linkage via O3-riboflavin phosphoryl-L-threonine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050740 RESID:AA0349 The formation of a protein-FMN linkage via O3-riboflavin phosphoryl-L-threonine. GO:0050745 peptide cross-linking via L-cysteinyl-5-imidazolinone glycine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050745 RESID:AA0188 The formation of a protein active site cross-link from the alpha-carboxyl carbon of residue N, a cysteine, to the alpha-amino nitrogen of residue N+2, a glycine, coupled with the formation of a double bond to the alpha-amino nitrogen of residue N+1 which loses one hydrogen, and the loss of a molecule of water. GO:0050746 regulation of lipoprotein metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050746 regulation of lipoprotein metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids. CHEBI:86490 C4-acylcarnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86490 GO:0050743 protein-FMN linkage via 1'-(8alpha-FMN)-L-histidine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050743 RESID:AA0352 The formation of a protein-FMN linkage via 1'-(8alpha-FMN)-L-histidine. CHEBI:86492 C5-acylcarnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86492 GO:0050744 protein-FMN linkage via 3'-(8alpha-FMN)-L-histidine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050744 RESID:AA0353 The formation of a protein-FMN linkage via 3'-(8alpha-FMN)-L-histidine. GO:0035190 syncytial nuclear migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035190 The directed movement of nuclei within the syncytial embryo of insects. These precise temporal and spatial patterns of nuclear movement are coordinated with mitotic divisons and are required during blastoderm formation to reposition dividing nuclei from the interior of the syncytial embryo to the cortex. GO:0050749 obsolete apolipoprotein E receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050749 apolipoprotein E receptor binding OBSOLETE. Interacting selectively with an apolipoprotein E receptor. CHEBI:86494 botanical anti-fungal agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86494 GO:0050747 positive regulation of lipoprotein metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050747 up regulation of lipoprotein metabolic process|activation of lipoprotein metabolic process|stimulation of lipoprotein metabolic process|up-regulation of lipoprotein metabolic process|positive regulation of lipoprotein metabolism|upregulation of lipoprotein metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids. GO:0050748 negative regulation of lipoprotein metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050748 down regulation of lipoprotein metabolic process|downregulation of lipoprotein metabolic process|down-regulation of lipoprotein metabolic process|inhibition of lipoprotein metabolic process|negative regulation of lipoprotein metabolism Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids. CHEBI:86496 acetyl-L-ornithine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86496 CHEBI:86497 hydroxykynurenine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86497 CHEBI:86498 hydroxylysine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86498 CHEBI:86499 monohydroxyproline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86499 GO:0035188 hatching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035188 The emergence of an immature organism from a protective structure. GO:0035189 Rb-E2F complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035189 retinoblastoma-E2F complex A multiprotein complex containing a heterodimeric E2F transcription factor and a Retinoblastoma (Rb) family member. This complex is capable of repressing transcription of E2F-regulated genes in order to regulate cell cycle progression. GO:0035180 larval wandering behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035180 larval wandering behaviour The movement of a third instar larva through a substrate in search of a pupation site. This movement occurs without feeding and is characterized by short bursts of forward movement, separated by stops and repeated side-to-side head probes, followed normally by a change in direction. GO:0035181 larval burrowing behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035181 larval burrowing behaviour Digging into the substrate by non-feeding larvae in search for food-free sites suitable for pupation. GO:0035182 female germline ring canal outer rim biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035182 germline ring canal outer rim|ovarian ring canal outer rim|nurse cell ring canal outer rim An electron opaque backbone of the insect ovarian ring canal that is a part of or adjacent to the plasma membrane. The outer rim is established as the cleavage furrow is arrested, and contains F-actin, anillin, glycoproteins and at least one a protein with a high content of phosphorylated tyrosine residues. GO:0035183 female germline ring canal inner rim biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035183 germline ring canal inner rim|ovarian ring canal inner rim|nurse cell ring canal inner rim A proteinaceous actin-rich layer of the insect ovarian ring canal that forms subcortically to the outer rim. The electron dense inner rim accumulates after the final mitotic division of each germline syncytia, and contains actin, a phosphotyrosine protein, and a number of cytoskeletal proteins. GO:0035184 histone threonine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035184 histone-threonine kinase activity Catalysis of the transfer of a phosphate group to a threonine residue of a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. GO:0035185 preblastoderm mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035185 The first nine mitotic division cycles of the insect embryo, during which the dividing nuclei lie deep in the interior of the egg and divide nearly synchronously. This is the first phase of the syncytial period where nuclei divide in a common cytoplasm without cytokinesis. GO:0035186 syncytial blastoderm mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035186 Mitotic division cycles 10 to 13 of the insect embryo. This is the second phase of the syncytial period where nuclei divide in a common cytoplasm without cytokinesis. The majority of migrating nuclei reach the embryo surface during cycle 10, after which they divide less synchronously than before, and the syncytial blastoderm cycles lengthen progressively. GO:0035187 hatching behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035187 hatching behaviour The specific behavior of an organism during the emergence from an egg shell. In Drosophila for example, the larva swings its head reiteratively through a semicircular arc, using its mouth hooks to tear apart the chorion in front of it and thus free itself from within the egg shell. GO:0050752 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050752 GO:0050753 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050753 GO:0050750 low-density lipoprotein particle receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050750 low-density lipoprotein receptor binding|LDL receptor binding Interacting selectively and non-covalently with a low-density lipoprotein receptor. GO:0050751 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050751 GO:0050756 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050756 GO:0050757 thymidylate synthase biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050757 thymidylate synthase anabolism|thymidylate synthase biosynthesis|thymidylate synthase synthesis|thymidylate synthase formation The chemical reactions and pathways resulting in the formation of the enzyme thymidylate synthase, which catalyzes the reaction: 5,10-methylenetetrahydrofolate + dUMP = dihydrofolate + dTMP. GO:0050754 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050754 GO:0050755 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050755 GO:0050758 regulation of thymidylate synthase biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050758 regulation of thymidylate synthase anabolism|regulation of thymidylate synthase synthesis|regulation of thymidylate synthase formation|regulation of thymidylate synthase biosynthesis Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the enzyme thymidylate synthase. GO:0050759 positive regulation of thymidylate synthase biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050759 positive regulation of thymidylate synthase formation|upregulation of thymidylate synthase biosynthetic process|up regulation of thymidylate synthase biosynthetic process|activation of thymidylate synthase biosynthetic process|positive regulation of thymidylate synthase biosynthesis|stimulation of thymidylate synthase biosynthetic process|positive regulation of thymidylate synthase anabolism|up-regulation of thymidylate synthase biosynthetic process|positive regulation of thymidylate synthase synthesis Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the enzyme thymidylate synthase. GO:0035177 larval foraging behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035177 larval foraging behaviour The movement of a larva through a feeding substrate whilst feeding on food. GO:0035178 turning behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035178 turning behaviour Fine-tuning the spatial position of an organism in response to variability in their environment. For example, reorientation of an organism in the direction of a food source. GO:0035179 larval turning behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035179 larval turning behaviour Fine-tuning the spatial position of a larva in response to variability in their environment. For example, reorientation of a larva in the direction of a food source. GO:0035170 lymph gland crystal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035170 The process in which a relatively unspecialized larval lymph gland-derived hemocyte precursor cell acquires the specialized features of a crystal cell. Crystal cells are a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph. GO:0035171 lamellocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035171 lamellocyte cell differentiation The process in which a relatively unspecialized hemocyte precursor cell acquires the specialized features of a lamellocyte. Lamellocytes are a hemocyte lineage that exists only in larvae, but are seldom observed in healthy animals. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes. GO:0035172 hemocyte proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035172 arthropod blood cell proliferation The multiplication or reproduction of hemocytes, resulting in the expansion of the cell population. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. GO:0035173 histone kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035173 Catalysis of the transfer of a phosphate group to a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. GO:0035174 histone serine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035174 histone-serine kinase activity Catalysis of the transfer of a phosphate group to a serine residue of a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. GO:0035175 histone kinase activity (H3-S10 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035175 histone kinase activity (H3-S3 specific)|histone serine kinase activity (H3-S10 specific)|histone-serine kinase activity (H3-S10 specific) Catalysis of the transfer of a phosphate group to the serine-10 residue of the N-terminal tail of histone H3. GO:0035176 social behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035176 Wikipedia:Social_behavior cooperative behavior|social behaviour Behavior directed towards society, or taking place between members of the same species. Occurs predominantly, or only, in individuals that are part of a group. GO:0050763 depsipeptide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050763 depsipeptide anabolism|depsipeptide synthesis|depsipeptide biosynthesis|depsipeptide formation The chemical reactions and pathways resulting in the formation of depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively. GO:0050764 regulation of phagocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050764 Any process that modulates the frequency, rate or extent of phagocytosis, the process in which phagocytes engulf external particulate material. GO:0050761 depsipeptide metabolic process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0050761 depsipeptide metabolism The chemical reactions and pathways involving depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively. GO:0050762 depsipeptide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050762 depsipeptide degradation|depsipeptide breakdown|depsipeptide catabolism The chemical reactions and pathways resulting in the breakdown of depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively. GO:0050767 regulation of neurogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050767 Any process that modulates the frequency, rate or extent of neurogenesis, the generation of cells in the nervous system. GO:0050768 negative regulation of neurogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050768 down-regulation of neurogenesis|downregulation of neurogenesis|down regulation of neurogenesis|inhibition of neurogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system. GO:0050765 negative regulation of phagocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050765 downregulation of phagocytosis|down regulation of phagocytosis|inhibition of phagocytosis|down-regulation of phagocytosis Any process that stops, prevents, or reduces the frequency, rate or extent of phagocytosis. GO:0050766 positive regulation of phagocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050766 up regulation of phagocytosis|upregulation of phagocytosis|stimulation of phagocytosis|activation of phagocytosis|up-regulation of phagocytosis Any process that activates or increases the frequency, rate or extent of phagocytosis. GO:0050769 positive regulation of neurogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050769 stimulation of neurogenesis|up-regulation of neurogenesis|activation of neurogenesis|up regulation of neurogenesis|upregulation of neurogenesis Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system. GO:0035166 post-embryonic hemopoiesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035166 post-embryonic haemopoiesis The stages of blood cell formation that take place after completion of embryonic development. GO:0035167 larval lymph gland hemopoiesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035167 larval lymph gland haemopoiesis|larval lymph gland hematopoiesis|larval lymph gland haematopoiesis The production of blood cells from the larval lymph gland. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages. GO:0035168 larval lymph gland hemocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035168 larval lymph gland arthropod blood cell differentiation The process in which a relatively unspecialized cell derived from the larval lymph gland acquires the specialized features of a mature hemocyte. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster. CHEBI:154293 alpha-D-GlcpNAc-(1->4)-D-GlcpNAc biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_154293 GO:0035169 lymph gland plasmatocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035169 lymph gland plasmatocyte cell differentiation The process in which a relatively unspecialized larval lymph gland-derived hemocyte precursor cell acquires the specialized features of the phagocytic blood-cell type, the plasmatocyte. GO:0035160 maintenance of epithelial integrity, open tracheal system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035160 maintenance of tracheal epithelial integrity Ensuring that tracheal tubes in an open tracheal system maintain their epithelial structure during the cell shape changes and movements that occur during the branching process. GO:0035161 imaginal disc lineage restriction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035161 Formation and/or maintenance of a lineage boundary between compartments in an imaginal disc that cells cannot cross, thus separating the populations of cells in each compartment. GO:0035162 embryonic hemopoiesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035162 embryonic hematopoiesis|embryonic haematopoiesis|embryonic haemopoiesis The stages of blood cell formation that take place within the embryo. GO:0050760 negative regulation of thymidylate synthase biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050760 negative regulation of thymidylate synthase anabolism|negative regulation of thymidylate synthase synthesis|inhibition of thymidylate synthase biosynthetic process|negative regulation of thymidylate synthase formation|down regulation of thymidylate synthase biosynthetic process|downregulation of thymidylate synthase biosynthetic process|negative regulation of thymidylate synthase biosynthesis|down-regulation of thymidylate synthase biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the enzyme thymidylate synthase. GO:0035163 embryonic hemocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035163 embryonic arthropod blood cell differentiation|embryonic hemocyte cell differentiation The process in which a relatively unspecialized cell derived from the embryonic head mesoderm acquires the specialized features of a mature hemocyte. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. GO:0035164 embryonic plasmatocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035164 embryonic plasmatocyte cell differentiation The process in which an embryonic mesoderm-derived hemocyte precursor cell acquires the specialized features of the phagocytic blood-cell type, the plasmatocyte. GO:0035165 embryonic crystal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035165 The process in which an embryonic mesoderm-derived hemocyte precursor cell acquires the specialized features of a crystal cell. Crystal cells are a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph. GO:0050774 negative regulation of dendrite morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050774 down-regulation of dendrite morphogenesis|downregulation of dendrite morphogenesis|down regulation of dendrite morphogenesis|inhibition of dendrite morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite morphogenesis. GO:0050775 positive regulation of dendrite morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050775 up regulation of dendrite morphogenesis|upregulation of dendrite morphogenesis|stimulation of dendrite morphogenesis|up-regulation of dendrite morphogenesis|activation of dendrite morphogenesis Any process that activates or increases the frequency, rate or extent of dendrite morphogenesis. GO:0050772 positive regulation of axonogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050772 upregulation of axonogenesis|stimulation of axonogenesis|up-regulation of axonogenesis|activation of axonogenesis|up regulation of axonogenesis Any process that activates or increases the frequency, rate or extent of axonogenesis. GO:0050773 regulation of dendrite development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050773 Any process that modulates the frequency, rate or extent of dendrite development. GO:0050778 positive regulation of immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050778 stimulation of immune response|up-regulation of immune response|upregulation of immune response|up regulation of immune response Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. GO:0050779 RNA destabilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050779 Any process that decreases the stability of an RNA molecule, making it more vulnerable to degradative processes. GO:0050776 regulation of immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050776 Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. GO:0050777 negative regulation of immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050777 down-regulation of immune response|inhibition of immune response|down regulation of immune response|downregulation of immune response Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. GO:0035155 negative regulation of terminal cell fate specification, open tracheal system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035155 downregulation of terminal cell fate specification|down regulation of terminal cell fate specification|inhibition of terminal cell fate specification|negative regulation of terminal cell fate specification|down-regulation of terminal cell fate specification Any process that restricts, stops or prevents a cell from adopting a terminal cell fate in an open tracheal system. Once the terminal and fusion fates have been correctly induced, inhibitory feedback loops prevent the remaining branch cells from assuming similar fates. GO:0035156 fusion cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035156 The process in which a cell becomes capable of differentiating autonomously into a fusion cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. Fusion cells allow the interconnection of adjacent tracheal metameres during tracheal tube fusion. GO:0035157 negative regulation of fusion cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035157 downregulation of fusion cell fate specification|down regulation of fusion cell fate specification|inhibition of fusion cell fate specification|down-regulation of fusion cell fate specification Any process that restricts, stops or prevents a cell from adopting a fusion cell fate. Once the terminal and fusion fates have been correctly induced, inhibitory feedback loops prevent the remaining branch cells from assuming similar fates. GO:0035158 regulation of tube diameter, open tracheal system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035158 regulation of tracheal tube diameter|tracheal tube expansion|tracheal tube dilation Ensuring that a tube in an open tracheal system is of the correct diameter. When primary branches form their lumens are small (less than 2 micrometers) in caliber and must undergo regulated expansion during larval life to reach their mature size. GO:0035159 regulation of tube length, open tracheal system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035159 tracheal tube elongation|regulation of tracheal tube length Ensuring that a tube in an open tracheal system is of the correct length. GO:0035150 regulation of tube size biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035150 Ensuring that a tube is of the correct length and diameter. Tube size must be maintained not only during tube formation, but also throughout development and in some physiological processes. GO:0050770 regulation of axonogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050770 Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron. GO:0035151 regulation of tube size, open tracheal system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035151 regulation of tracheal tube size Ensuring that an epithelial tube in an open tracheal system is of the correct length and diameter. Tracheal tubes undergo highly regulated tube-size increases during development, expanding up to 40 times their initial size by the end of larval life. Tube size appears to be controlled by regulation of apical membrane expansion and secretion, rather than by changes in cell number, size or shape. GO:0050771 negative regulation of axonogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050771 down regulation of axonogenesis|inhibition of axonogenesis|down-regulation of axonogenesis|downregulation of axonogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of axonogenesis. GO:0035152 regulation of tube architecture, open tracheal system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035152 regulation of tracheal tube architecture Ensuring that tracheal cells form and maintain tubular structures with the correct size and shape for their position in the network. This is essential for efficient flow of gases through the tracheal network. GO:0035153 epithelial cell type specification, open tracheal system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035153 tracheal cell type specification|tracheal epithelial cell type specification Allocation of epithelial cells within each migrating branch in an open tracheal system to distinct tracheal cell fates. During the migration phase each branch forms a well-defined number of cell types (including fusion cells, terminal cells and branch cells) at precise positions. GO:0035154 terminal cell fate specification, open tracheal system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035154 terminal cell fate specification The process in which a cell in an open tracheal system becomes capable of differentiating autonomously into a terminal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. Terminal cells send long and bifurcated hollow branches toward target tissues to allow oxygen exchange. UBERON:0000219 vertebral foramen of atlas biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000219 vertebral foramen of cervical vertebra 1 . GO:0001930 positive regulation of exocyst assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001930 up regulation of exocyst assembly|upregulation of exocyst assembly|stimulation of exocyst assembly|activation of exocyst assembly|up-regulation of exocyst assembly Any process that increases the rate or extent of exocyst assembly. GO:0001931 uropod biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001931 distal pole complex|retractile pole|uropodium A membrane projection with related cytoskeletal components at the trailing edge of a cell in the process of migrating or being activated, found on the opposite side of the cell from the leading edge or immunological synapse, respectively. UBERON:0000218 vertebral arch of axis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000218 vertebral foramen of cervical vertebra 2 A neural arch that is part of a vertebral bone 2. CHEBI:37433 gulonolactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37433 CHEBI:37434 ribonolactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37434 CHEBI:62406 3-hydroxydecanoyl-3-hydroxydecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62406 CHEBI:62407 UDP-N-acetyl-beta-L-fucosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62407 GO:0001936 regulation of endothelial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001936 Any process that modulates the frequency, rate, or extent of endothelial cell proliferation. GO:0001937 negative regulation of endothelial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001937 down-regulation of endothelial cell proliferation|downregulation of endothelial cell proliferation|down regulation of endothelial cell proliferation|inhibition of endothelial cell proliferation Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation. GO:0001938 positive regulation of endothelial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001938 stimulation of endothelial cell proliferation|up-regulation of endothelial cell proliferation|activation of endothelial cell proliferation|up regulation of endothelial cell proliferation|upregulation of endothelial cell proliferation Any process that activates or increases the rate or extent of endothelial cell proliferation. CHEBI:62408 trans,trans-octa-2,4-dienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62408 CHEBI:62409 trans,trans-deca-2,4-dienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62409 GO:0001939 female pronucleus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001939 The pronucleus originating from the ovum that is being fertilized. GO:0001932 regulation of protein phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001932 regulation of protein amino acid phosphorylation Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein. CHEBI:37431 uronolactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37431 GO:0001933 negative regulation of protein phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001933 down-regulation of protein amino acid phosphorylation|downregulation of protein amino acid phosphorylation|down regulation of protein amino acid phosphorylation|inhibition of protein amino acid phosphorylation|negative regulation of protein amino acid phosphorylation Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein. CHEBI:37432 mannonolactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37432 UBERON:0000220 atlanto-occipital joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000220 occipito-atlantal joint|articulatio atlanto-occipitalis|craniovertebral joint|atlanto occipital joint|atlantooccipital joint|occipito atlantal joint|articulatio atlantooccipitalis The Atlanto-occipital joint (articulation between the atlas and the occipital bone) consists of a pair of condyloid joints. The atlanto-occipital joint is a synovial joint. The ligaments connecting the bones are: Two Articular capsules; Posterior atlantoöccipital membrane; Anterior atlantoöccipital membrane; Lateral atlantoöccipital GO:0001934 positive regulation of protein phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001934 positive regulation of protein amino acid phosphorylation|stimulation of protein amino acid phosphorylation|up-regulation of protein amino acid phosphorylation|activation of protein amino acid phosphorylation|up regulation of protein amino acid phosphorylation|upregulation of protein amino acid phosphorylation Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein. GO:0001935 endothelial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001935 The multiplication or reproduction of endothelial cells, resulting in the expansion of a cell population. Endothelial cells are thin flattened cells which line the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium. UBERON:0000209 tetrapod frontal bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000209 os frontale|os frontal|frontal|frontal bone the bone forming the forehead and roof of the eye orbit GO:0001940 male pronucleus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001940 The pronucleus originating from the spermatozoa that was involved in fertilization. GO:0001941 postsynaptic membrane organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001941 postsynaptic membrane organisation|post-synaptic membrane organization A process which results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic membrane, the specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). GO:0001942 hair follicle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001942 The process whose specific outcome is the progression of the hair follicle over time, from its formation to the mature structure. A hair follicle is a tube-like opening in the epidermis where the hair shaft develops and into which the sebaceous glands open. UBERON:0000204 ventral part of telencephalon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000204 area ventralis telencephali|subpallium|subpallium|ventral telencephalon Ventral part (base region) of the telencephalon. UBERON:0000207 compound eye corneal lens biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000207 acellular lens A chitinous extracellular secretion of the four underlying cone cells and the pigment cells. UBERON:0014852 chorda tendinea of right ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014852 Chorda tendinea which is attached to the leaflet of tricuspid valve and is continuous with the endocardium of papillary muscle of right ventricle. CHEBI:62410 UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62410 UBERON:0014851 chorda tendinea of left ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014851 Chorda tendinea which is attached to the leaflet of mitral valve and is continuous with the endocardium of papillary muscle of left ventricle. CHEBI:62413 (S)-methylmalonate semialdehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62413 CHEBI:62414 biotinyl-5'-AMP(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62414 CHEBI:62411 UDP-2-acetamido-2,6-dideoxy-beta-L-talose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62411 CHEBI:37445 folic acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37445 CHEBI:62412 phenazine-1-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62412 CHEBI:62417 arabidiol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62417 CHEBI:62418 3-oxohexanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62418 CHEBI:37448 2-dehydro-3-deoxy-L-fuconate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37448 CHEBI:37449 2-deoxy-alpha-D-glucoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37449 CHEBI:62416 dammarenediol-II biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62416 GO:0001947 heart looping biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001947 cardiac looping The tube morphogenesis process in which the primitive heart tube loops asymmetrically. This looping brings the primitive heart chambers into alignment preceding their future integration. Heart looping begins with dextral-looping and ends when the main regional divisions of the mature heart and primordium of the great arterial trunks become established preceeding septation. UBERON:0000211 ligament biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000211 ligament organ Dense regular connective tissue connecting two or more adjacent skeletal elements or supporting an organ. GO:0001948 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001948 CHEBI:62419 (1R,2S)-epoxypropylphosphonate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62419 GO:0001949 sebaceous gland cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001949 sebocytes differentiation The process in which a relatively unspecialized epidermal cell acquires the specialized features of a sebaceous gland cell. GO:0001943 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001943 GO:0001944 vasculature development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001944 vascular system development The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism. GO:0001945 lymph vessel development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001945 The process whose specific outcome is the progression of a lymph vessel over time, from its formation to the mature structure. CHEBI:37440 3-oxoadipic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37440 UBERON:0000210 tetrapod parietal bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000210 parietal|parietal bone|os parietale|actinopterygian frontal bone|frontal bone In humans: bone forming side and roof of cranium. Each bone is irregularly quadrilateral in form, and has two surfaces, four borders, and four angles. GO:0001946 lymphangiogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001946 Wikipedia:Lymphangiogenesis lymph vessel formation Lymph vessel formation when new vessels emerge from the proliferation of pre-existing vessels. NCBITaxon:35493 Streptophyta organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_35493 CHEBI:62420 UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-hex-4-ulose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62420 CHEBI:62421 (S)-2-trans-abscisate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62421 CHEBI:62424 UDP-2-acetamido-2-deoxy-alpha-D-ribo-hex-3-uloseuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62424 CHEBI:62423 (2-hydroxyphenyl)acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62423 CHEBI:37412 phosphoshikimic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37412 GO:0001918 farnesylated protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001918 Interacting selectively and non-covalently with a farnesylated protein. CHEBI:62428 UDP-2-acetamido-2,6-dideoxy-beta-L-lyxo-hex-4-ulose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62428 CHEBI:62429 2-trans-abscisate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62429 GO:0001919 regulation of receptor recycling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001919 Any process that modulates the frequency, rate, or extent of receptor recycling. CHEBI:13488 UDP-D-galacturonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_13488 CHEBI:62426 2-trans-abscisic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62426 CHEBI:37416 EC 2.7.7.6 (RNA polymerase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37416 GO:0001914 regulation of T cell mediated cytotoxicity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001914 regulation of T lymphocyte mediated cytotoxicity|regulation of T-cell mediated cell death|regulation of T-cell mediated apoptosis|regulation of T cell mediated cell death|regulation of T cell mediated cytolysis|regulation of T-cell mediated cytotoxicity|regulation of T-cell mediated cell killing|regulation of T-lymphocyte mediated cytotoxicity|regulation of T cell mediated apoptosis|regulation of T-cell mediated cytolysis|regulation of T cell mediated cell killing Any process that modulates the frequency, rate, or extent of T cell mediated cytotoxicity. UBERON:0000200 gyrus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000200 gyri|gyrus of cerebrum|gyrus of neuraxis|folium|folia|neuraxis gyrus|cerebral gyrus|folium of brain|gyrus of cerebral hemisphere|gyri of cerebrum A ridge on the cerebral cortex. It is generally surrounded by one or more sulci . GO:0001915 negative regulation of T cell mediated cytotoxicity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001915 down regulation of T cell mediated cytotoxicity|inhibition of T cell mediated cytotoxicity|negative regulation of T cell mediated apoptosis|negative regulation of T cell mediated cell death|negative regulation of T-cell mediated cytotoxicity|negative regulation of T-cell mediated cytolysis|negative regulation of T-cell mediated cell killing|negative regulation of T-lymphocyte mediated cytotoxicity|negative regulation of T-cell mediated apoptosis|down-regulation of T cell mediated cytotoxicity|negative regulation of T cell mediated cell killing|negative regulation of T lymphocyte mediated cytotoxicity|negative regulation of T-cell mediated cell death|negative regulation of T cell mediated cytolysis|downregulation of T cell mediated cytotoxicity Any process that stops, prevents, or reduces the rate of T cell mediated cytotoxicity. UBERON:0000201 endothelial blood brain barrier biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000201 A blood brain barrier that is composed of endothelial cells. GO:0001916 positive regulation of T cell mediated cytotoxicity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001916 upregulation of T cell mediated cytotoxicity|positive regulation of T-cell mediated cytolysis|positive regulation of T cell mediated cell death|positive regulation of T-cell mediated cytotoxicity|stimulation of T cell mediated cytotoxicity|positive regulation of T-cell mediated cell killing|positive regulation of T-cell mediated apoptosis|up-regulation of T cell mediated cytotoxicity|activation of T cell mediated cytotoxicity|positive regulation of T-lymphocyte mediated cytotoxicity|positive regulation of T cell mediated cytolysis|up regulation of T cell mediated cytotoxicity|positive regulation of T cell mediated cell killing|positive regulation of T lymphocyte mediated cytotoxicity|positive regulation of T-cell mediated cell death|positive regulation of T cell mediated apoptosis Any process that activates or increases the frequency, rate or extent of T cell mediated cytotoxicity. UBERON:0000203 pallium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000203 dorsal part of telencephalon|dorsal telencephalon|dorsal telencephalic area|area dorsalis telencephali Dorsal part (roof region) of the telencephalon[GO]. GO:0001917 photoreceptor inner segment biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0001917 The inner segment of a vertebrate photoreceptor containing mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs. GO:0001910 regulation of leukocyte mediated cytotoxicity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001910 regulation of leucocyte mediated cytotoxicity|regulation of immune cell mediated cell death|regulation of immune cell mediated cytotoxicity|regulation of immune cell mediated cell killing Any process that modulates the frequency, rate, or extent of leukocyte mediated cytotoxicity. GO:0001911 negative regulation of leukocyte mediated cytotoxicity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001911 down regulation of leukocyte mediated cytotoxicity|downregulation of leukocyte mediated cytotoxicity|negative regulation of leucocyte mediated cytotoxicity|down-regulation of leukocyte mediated cytotoxicity|inhibition of leukocyte mediated cytotoxicity|negative regulation of immune cell mediated cytotoxicity Any process that stops, prevents, or reduces the rate of leukocyte mediated cytotoxicity. GO:0001912 positive regulation of leukocyte mediated cytotoxicity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001912 upregulation of leukocyte mediated cytotoxicity|positive regulation of leucocyte mediated cytotoxicity|up regulation of leukocyte mediated cytotoxicity|activation of leukocyte mediated cytotoxicity|stimulation of leukocyte mediated cytotoxicity|positive regulation of immune cell mediated cytotoxicity|up-regulation of leukocyte mediated cytotoxicity Any process that activates or increases the frequency, rate or extent of leukocyte mediated cytotoxicity. GO:0001913 T cell mediated cytotoxicity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001913 T cell mediated cell death|T-cell mediated cytotoxicity|T cell mediated apoptosis|T-cell mediated cell killing|T-lymphocyte mediated cytotoxicity|T-cell mediated apoptosis|T cell mediated cell killing|T lymphocyte mediated cytotoxicity|T-cell mediated cell death|T cell mediated cytolysis The directed killing of a target cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors. GO:0001920 negative regulation of receptor recycling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001920 downregulation of receptor recycling|down regulation of receptor recycling|inhibition of receptor recycling|down-regulation of receptor recycling Any process that stops, prevents, or reduces the rate of receptor recycling. CHEBI:62431 abscisic acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62431 CHEBI:62432 abscisates biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62432 CHEBI:37424 sterol 3-beta-D-glucoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37424 CHEBI:62436 (+)-abscisic acid D-glucopyranosyl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62436 CHEBI:37425 L-galactonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37425 CHEBI:37422 arabinono-1,4-lactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37422 CHEBI:62433 (R)-2-trans-abscisate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62433 GO:0001929 negative regulation of exocyst assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001929 downregulation of exocyst assembly|down regulation of exocyst assembly|inhibition of exocyst assembly|down-regulation of exocyst assembly Any process that stops, prevents, or reduces the rate or extent of exocyst assembly. CHEBI:62439 soyasapogenol B 3-O-beta-glucuronide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62439 CHEBI:37429 aldonolactone phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37429 CHEBI:37426 aldarolactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37426 CHEBI:62437 (S)-2-trans-abscisic acid beta-D-glucopyranosyl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62437 CHEBI:37427 ketoaldonolactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37427 CHEBI:62438 (S)-2-trans-abscisic acid D-glucopyranosyl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62438 GO:0001925 negative regulation of B-1 B cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001925 negative regulation of B-1 B-lymphocyte differentiation|negative regulation of B-1 B cell development|down-regulation of B-1 B cell differentiation|negative regulation of B-1 B lymphocyte differentiation|downregulation of B-1 B cell differentiation|down regulation of B-1 B cell differentiation|inhibition of B-1 B cell differentiation|negative regulation of B-1 B-cell differentiation Any process that stops, prevents, or reduces the rate of B-1 B cell differentiation. GO:0001926 positive regulation of B-1 B cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001926 stimulation of B-1 B cell differentiation|positive regulation of B-1 B-cell differentiation|up-regulation of B-1 B cell differentiation|activation of B-1 B cell differentiation|positive regulation of B-1 B-lymphocyte differentiation|positive regulation of B-1 B cell development|up regulation of B-1 B cell differentiation|positive regulation of B-1 B lymphocyte differentiation|upregulation of B-1 B cell differentiation Any process that activates or increases the frequency, rate or extent of B-1 B cell differentiation. GO:0001927 exocyst assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001927 The aggregation, arrangement and bonding together of various polypeptides into the exocyst complex. GO:0001928 regulation of exocyst assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001928 Any process that modulates the frequency, rate or extent of exocyst assembly. GO:0001921 positive regulation of receptor recycling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001921 up regulation of receptor recycling|upregulation of receptor recycling|stimulation of receptor recycling|up-regulation of receptor recycling|activation of receptor recycling Any process that activates or increases the frequency, rate or extent of receptor recycling. CHEBI:37420 12-hydroxyjasmonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37420 GO:0001922 B-1 B cell homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001922 B-1 B lymphocyte homeostasis|B-1 B-cell homeostasis|B-1 B-lymphocyte homeostasis The process of regulating the proliferation and elimination of B cells of the B-1 subset such that the total number of B-1 B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity. CHEBI:37421 carbohydrate lactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37421 GO:0001923 B-1 B cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001923 B-1 B cell development|B-1 B lymphocyte differentiation|B-1 B-cell differentiation|B-1 B-lymphocyte differentiation The process in which a hemopoietic stem cell acquires the specialized features of a B-1 B cell. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity. GO:0001924 regulation of B-1 B cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001924 regulation of B-1 B-cell differentiation|regulation of B-1 B-lymphocyte differentiation|regulation of B-1 B cell development|regulation of B-1 B lymphocyte differentiation Any process that modulates the frequency, rate, or extent of B-1 B cell differentiation. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity. GO:0050900 leukocyte migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050900 leucocyte trafficking|leucocyte migration|leukocyte trafficking|immune cell trafficking|immune cell migration The movement of a leukocyte within or between different tissues and organs of the body. GO:0050903 leukocyte activation-dependent arrest biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050903 The formation of an integrin-dependent strong adhesive bond between leukocytes and blood vessel endothelial cells which is dependent on prior activation of the leukocyte and leads to the firm attachment of the leukocyte to the endothelial surface, typically the third step in cellular extravasation. GO:0050904 diapedesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050904 The passage of a leukocyte between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation. GO:0050901 leukocyte tethering or rolling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050901 Transient adhesive interactions between leukocytes and endothelial cells lining blood vessels. Carbohydrates on circulating leukocytes bind selectins on the vessel wall causing the leukocytes to slow down and roll along the inner surface of the vessel wall. During this rolling motion, transitory bonds are formed and broken between selectins and their ligands. Typically the first step in cellular extravasation (the movement of leukocytes out of the circulatory system, towards the site of tissue damage or infection). GO:0050902 leukocyte adhesive activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050902 leukocyte adhesive triggering The activation of loosely bound or rolling leukocytes by signals displayed on blood vessel endothelial cells, which is typically the second step in cellular extravasation. CHEBI:62442 soyasapogenol A 3-O-beta-glucuronide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62442 GO:0050907 detection of chemical stimulus involved in sensory perception biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050907 sensory perception, sensory transduction of chemical stimulus|sensory transduction of chemical stimulus during sensory perception|sensory transduction of chemical stimulus|sensory detection of chemical stimulus during sensory perception|sensory detection of chemical stimulus|sensory perception, sensory detection of chemical stimulus The series of events in which a chemical stimulus is received and converted into a molecular signal as part of sensory perception. CHEBI:62443 soyasapogenol A 3-O-beta-glucuronate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62443 GO:0050908 detection of light stimulus involved in visual perception biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050908 visual perception, sensory transduction of light stimulus|sensory detection of light during visual perception|sensory transduction of light stimulus during visual perception|visual perception, detection of light stimulus|sensory transduction of light during visual perception|sensory detection of light stimulus during visual perception|visual perception, sensory transduction during perception of light The series of events involved in visual perception in which a light stimulus is received and converted into a molecular signal. CHEBI:62440 soyasapogenol A biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62440 GO:0050905 neuromuscular process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050905 neuromotor process|neuromuscular physiological process Any process pertaining to the functions of the nervous and muscular systems of an organism. CHEBI:62441 soyasapogenol B 3-O-beta-glucuronate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62441 GO:0050906 detection of stimulus involved in sensory perception biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050906 Wikipedia:Transduction_(physiology) sensory detection of stimulus|sensory transduction|sensory perception, sensory transduction of stimulus|sensory perception, stimulus detection The series of events involved in sensory perception in which a sensory stimulus is received and converted into a molecular signal. CHEBI:86412 3-oxochol-4-en-24-oyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86412 CHEBI:62446 soyasapogenol E 3-O-beta-glucuronate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62446 GO:2001196 positive regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001196 positive regulation of lysine biosynthetic process via aminoadipic acid and saccharopine|positive regulation of lysine biosynthesis via aminoadipic acid and saccharopine Any process that activates or increases the frequency, rate or extent of lysine biosynthetic process via alpha-aminoadipate and saccharopine. CHEBI:62447 dammara-20,24-diene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62447 GO:2001197 basement membrane assembly involved in embryonic body morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001197 Any basement membrane assembly that is involved in embryonic body morphogenesis. CHEBI:86414 3-oxocholesta-4,24-dien-26-oyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86414 CHEBI:62444 soyasapogenol E biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62444 GO:2001198 regulation of dendritic cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001198 Any process that modulates the frequency, rate or extent of dendritic cell differentiation. GO:2001199 negative regulation of dendritic cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001199 Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell differentiation. CHEBI:62445 soyasapogenol E 3-O-beta-glucuronide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62445 CHEBI:62448 indole-3-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62448 CHEBI:62449 4,4'-diapolycopene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62449 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001190 positive regulation of T-cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell|positive regulation of T lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell|positive regulation of T-lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell Any process that activates or increases the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell. GO:2001191 regulation of gamma-delta T cell activation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001191 regulation of gamma-delta T lymphocyte activation during immune response|regulation of gamma-delta T-cell activation during immune response|regulation of gamma-delta T-lymphocyte activation during immune response|regulation of gamma-delta T cell activation during immune response Any process that modulates the frequency, rate or extent of gamma-delta T cell activation involved in immune response. GO:2001192 negative regulation of gamma-delta T cell activation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001192 negative regulation of gamma-delta T-cell activation during immune response|negative regulation of gamma-delta T-lymphocyte activation during immune response|negative regulation of gamma-delta T cell activation during immune response|negative regulation of gamma-delta T lymphocyte activation during immune response Any process that stops, prevents or reduces the frequency, rate or extent of gamma-delta T cell activation involved in immune response. GO:2001193 positive regulation of gamma-delta T cell activation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001193 positive regulation of gamma-delta T-cell activation during immune response|positive regulation of gamma-delta T-lymphocyte activation during immune response|positive regulation of gamma-delta T cell activation during immune response|positive regulation of gamma-delta T lymphocyte activation during immune response Any process that activates or increases the frequency, rate or extent of gamma-delta T cell activation involved in immune response. GO:2001194 regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001194 regulation of lysine biosynthesis via aminoadipic acid and saccharopine|regulation of lysine biosynthetic process via aminoadipic acid and saccharopine Any process that modulates the frequency, rate or extent of lysine biosynthetic process via alpha-aminoadipate and saccharopine. GO:2001195 negative regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001195 negative regulation of lysine biosynthesis via aminoadipic acid and saccharopine|negative regulation of lysine biosynthetic process via aminoadipic acid and saccharopine Any process that stops, prevents or reduces the frequency, rate or extent of lysine biosynthetic process via alpha-aminoadipate and saccharopine. UBERON:0014891 brainstem white matter biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014891 brainstem tracts|brainstem tracts and commissures|brainstem tract/commissure|brain stem white matter White matter that is part of a brainstem [Automatically generated definition]. GO:0050910 detection of mechanical stimulus involved in sensory perception of sound biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050910 perception of sound, sensory detection of mechanical stimulus|perception of sound, detection of mechanical stimulus|perception of sound, sensory transduction of mechanical stimulus|sensory transduction of sound|sensory detection of mechanical stimulus during perception of sound|detection of sound|hearing, sensory transduction of sound|sensory transduction of mechanical stimulus during perception of sound The series of events involved in the perception of sound vibration in which the vibration is received and converted into a molecular signal. GO:0050911 detection of chemical stimulus involved in sensory perception of smell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050911 sensory transduction of scent|perception of smell, sensory transduction of chemical stimulus|sensory detection of scent|perception of smell, sensory detection of chemical stimulus|perception of smell, detection of chemical stimulus|sensory detection of chemical stimulus during perception of smell|sensory transduction of smell|sensory transduction of chemical stimulus during perception of smell|sensory detection of smell The series of events involved in the perception of smell in which an olfactory chemical stimulus is received and converted into a molecular signal. GO:0050914 sensory perception of salty taste biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050914 salty taste perception The series of events required to receive a salty taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. UBERON:0014896 transversely striated somatic muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014896 A somatic muscle that consists of one or more somatic muscle myotubes and any associated extracellular structures. GO:0050915 sensory perception of sour taste biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050915 sour taste perception The series of events required to receive a sour taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. CHEBI:62450 4,4'-diapolycopenedial biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62450 GO:0050912 detection of chemical stimulus involved in sensory perception of taste biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050912 sensory transduction of taste|sensory detection of chemical stimulus during perception of taste|sensory detection of taste|sensory transduction of chemical stimulus during perception of taste|taste perception|perception of taste, sensory transduction of chemical stimulus|perception of taste, sensory detection of chemical stimulus|perception of taste, detection of chemical stimulus The series of events involved in the perception of taste in which a gustatory chemical stimulus is received and converted into a molecular signal. GO:0050913 sensory perception of bitter taste biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050913 bitter taste perception The series of events required to receive a bitter taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. CHEBI:37409 crown compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37409 GO:0050918 positive chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050918 chemoattraction The directed movement of a motile cell or organism towards a higher concentration of a chemical. UBERON:0014892 skeletal muscle organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014892 skeletal muscle A muscle organ that consists of skeletal muscle tissue ensheathed in epimysium, that develops from myotome and that is innervated by some somatic motor neuron. Skeletal muscles are typically attached (via a tendon) to a bone but there are exceptions (e.g. intrinsic tongue muscles). GO:0050919 negative chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050919 chemoaversion|chemorepulsion The directed movement of a motile cell or organism towards a lower concentration of a chemical. GO:0050916 sensory perception of sweet taste biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050916 sweet taste perception The series of events required to receive a sweet taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. CHEBI:86400 levodione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86400 PR:000009001 interleukin-23 receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000009001 IL-23 receptor|IL23R|IL-23R A protein that is a translation product of the human IL23R gene or a 1:1 ortholog thereof. GO:0050917 sensory perception of umami taste biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050917 umami taste perception The series of events required to receive an umami taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. Umami taste is the savory taste of meats and other foods that are rich in glutamates. This is a neurological process. CHEBI:86401 N-Acetyldemethylphosphinothricinate (2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86401 UBERON:0014895 somatic muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014895 skeletal muscle A muscle structure of invertebrates whose origin and insertion sites are in basal side of the epidermis or structures derived from it. The simplest somatic muscles consist of a single cell and associated extracellular structures. CHEBI:62452 camelliol C biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62452 CHEBI:62457 (17Z)-protosta-17(20),24-dien-3beta-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62457 CHEBI:62458 sophoradiol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62458 GO:0050909 sensory perception of taste biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050909 Wikipedia:Taste gustation|sense of taste|taste|taste perception The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process. CHEBI:62455 germanicol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62455 CHEBI:62456 cucurbitadienol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62456 GO:0001907 killing by symbiont of host cells biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001907 Any process mediated by an organism that results in the death of cells in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:37407 cyclic ether biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37407 GO:0001908 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001908 GO:0001909 leukocyte mediated cytotoxicity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001909 leucocyte mediated cytotoxicity|immune cell mediated cell death|immune cell mediated cytotoxicity|immune cell mediated cell killing The directed killing of a target cell by a leukocyte. CHEBI:62459 24-hydroxy-beta-amyrin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62459 CHEBI:37404 elemental copper biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37404 GO:0001903 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001903 GO:0001904 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001904 GO:0001905 activation of membrane attack complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001905 activation of TCC|membrane attack complex assembly|MAC formation|activation of the terminal complement cascade|MAC assembly|activation of terminal complement complex|activation of MAC|membrane attack complex formation The activation of the membrane attack complex components of the complement cascade which can result in death of a target cell through cytolysis. GO:0001906 cell killing biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0001906 necrosis Any process in an organism that results in the killing of its own cells or those of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions. GO:0001900 positive regulation of cytolysis by symbiont of host cells biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001900 upregulation by symbiont of cytolysis of host cells|positive regulation by symbiont of cytolysis of host cells|up regulation by symbiont of cytolysis of host cells|activation by symbiont of cytolysis of host cells|stimulation by symbiont of cytolysis of host cells|up-regulation by symbiont of cytolysis of host cells Any process in which an organism activates or increases the frequency, rate or extent of cytolysis by that organism of cells in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0001901 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001901 GO:0001902 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001902 GO:0050921 positive regulation of chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050921 upregulation of chemotaxis|stimulation of chemotaxis|up-regulation of chemotaxis|activation of chemotaxis|up regulation of chemotaxis Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient. GO:0050922 negative regulation of chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050922 down regulation of chemotaxis|inhibition of chemotaxis|down-regulation of chemotaxis|downregulation of chemotaxis Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient. GO:0050920 regulation of chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050920 Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient. GO:0050925 negative regulation of negative chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050925 down-regulation of negative chemotaxis|inhibition of negative chemotaxis|down regulation of negative chemotaxis|downregulation of negative chemotaxis Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical. CHEBI:62460 helvolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62460 GO:0050926 regulation of positive chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050926 Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical. UBERON:0014886 distal epiphysis of distal phalanx of manual digit biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014886 head of distal phalanx of digit of manus|distal end of distal phalanx of finger|head of distal phalanx of digit of hand|head of distal phalanx of finger CHEBI:62461 helvolate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62461 UBERON:0014887 distal epiphysis of distal phalanx of digit biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014887 head of distal phalanx of digit of autopod|head of distal phalanx|head of distal phalanx of digit|distal end of distal phalanx of digit A distal epiphysis that is part of a distal phalanx. GO:0050923 regulation of negative chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050923 Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical. GO:0050924 positive regulation of negative chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050924 activation of negative chemotaxis|stimulation of negative chemotaxis|up-regulation of negative chemotaxis|upregulation of negative chemotaxis|up regulation of negative chemotaxis Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical. GO:0050929 induction of negative chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050929 Any process that initiates the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical. CHEBI:62464 O-(3-O-beta-D-galactosyl-N-acetyl-alpha-D-galactosaminyl)-L-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62464 CHEBI:62465 O-(3-O-beta-D-galactosyl-N-acetyl-alpha-D-galactosaminyl)-L-serine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62465 GO:0050927 positive regulation of positive chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050927 up regulation of positive chemotaxis|activation of positive chemotaxis|stimulation of positive chemotaxis|up-regulation of positive chemotaxis|upregulation of positive chemotaxis Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical. CHEBI:86433 4-hydroxybenzoyl-AMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86433 CHEBI:62462 isoguanine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62462 CHEBI:86434 (25R)-3beta,4beta-dihydroxycholest-5-en-26-oic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86434 GO:0050928 negative regulation of positive chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050928 downregulation of positive chemotaxis|down-regulation of positive chemotaxis|inhibition of positive chemotaxis|down regulation of positive chemotaxis Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical. CHEBI:62463 7,9,9'-tri-cis-neurosporene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62463 CHEBI:86435 4-hydroxybenzoyl-AMP(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86435 CHEBI:62466 7,7',9,9'-tetra-cis-lycopene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62466 GO:0050932 regulation of pigment cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050932 Any process that modulates the frequency, rate or extent of pigmented cell differentiation. GO:0050933 early stripe melanocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050933 early stripe melanophore differentiation|early stripe melanocyte cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of an early stripe melanocyte (ESM). In zebrafish, ESMs develop during the first phase (2-3 weeks of development) of the larva to adult transition (2-4 weeks of development). GO:0050930 induction of positive chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050930 Any process that initiates the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical. GO:0050931 pigment cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050931 chromatophore differentiation|pigmented cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a pigmented cell, such as a melanocyte. GO:0050936 xanthophore differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050936 xanthophore cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a xanthophore cell. Xanthophores are pigment cells derived from the neural crest. They contain pteridine and/or carotenoid pigments in structures called pterinosomes or xanthosomes. This makes them yellow to orange in appearance. GO:0050937 regulation of iridophore differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050937 Any process that modulates the frequency, rate or extent of iridophore differentiation. GO:0050934 late stripe melanocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050934 late stripe melanophore differentiation|late stripe melanocyte cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a late stripe melanocyte (LSM). In zebrafish, LSMs develop during the second phase (3-4 weeks of development) of the larva-to-adult transition (2-4 weeks of development). UBERON:0014876 distal epiphysis of distal phalanx of pedal digit biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014876 head of distal phalanx of toe|head of distal phalanx of digit of foot|distal end of distal phalanx of toe|head of distal phalanx of digit of pes GO:0050935 iridophore differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050935 iridophore cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of an iridophore. Iridophores are pigment cells derived from the neural crest. They contain guanidine or other purine crystals deposited in stacks called reflecting platets or iridisomes. This gives them a silver, gold, or iridescent appearance. CHEBI:86420 imidazole antifungal agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86420 CHEBI:62476 2-O-(4-deoxy-beta-L-threo-hex-4-enopyranuronosyl)-alpha-L-rhamnopyranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62476 CHEBI:86421 2-nitrophenols biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86421 GO:0050938 regulation of xanthophore differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050938 Any process that modulates the frequency, rate or extent of xanthophore differentiation. GO:0050939 regulation of early stripe melanocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050939 regulation of early stripe melanophore differentiation Any process that modulates the frequency, rate or extent of early stripe melanocyte differentiation. CHEBI:62474 all-trans-3,4-didehydrolycopene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62474 CHEBI:86426 triazole antifungal agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86426 CHEBI:62478 2-O-(4-deoxy-beta-L-threo-hex-4-enopyranuronosyl)-alpha-L-rhamnopyranose(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62478 GO:0035306 positive regulation of dephosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035306 up-regulation of dephosphorylation|upregulation of dephosphorylation|up regulation of dephosphorylation|activation of dephosphorylation|stimulation of dephosphorylation Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a molecule. GO:0035307 positive regulation of protein dephosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035307 activation of protein amino acid dephosphorylation|up regulation of protein amino acid dephosphorylation|upregulation of protein amino acid dephosphorylation|positive regulation of protein amino acid dephosphorylation|stimulation of protein amino acid dephosphorylation|up-regulation of protein amino acid dephosphorylation Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a protein. GO:0035308 negative regulation of protein dephosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035308 down-regulation of protein amino acid dephosphorylation|downregulation of protein amino acid dephosphorylation|down regulation of protein amino acid dephosphorylation|inhibition of protein amino acid dephosphorylation|negative regulation of protein amino acid dephosphorylation Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a protein. GO:0035309 wing and notum subfield formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035309 The regionalization process that subdivides the wing imaginal disc into the wing and notum (body wall) subfields, thus determining whether cells ultimately differentiate wing or notum-specific structures. GO:0035300 obsolete inositol-1,3,4-trisphosphate 5/6-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035300 IP56K|inositol trisphosphate 5/6-kinase activity|Ins(1,3,4)P3 5/6-kinase activity|inositol 1,3,4-trisphosphate 6-kinase activity|inositol 1,3,4-trisphosphate 5-kinase activity|ATP:1D-myo-inositol 1,3,4-trisphosphate 5-phosphotransferase activity|inositol-1,3,4-trisphosphate 5/6-kinase activity OBSOLETE. Catalysis of the reactions: ATP + 1D-myo-inositol 1,3,4-trisphosphate = ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate, and ATP + 1D-myo-inositol 1,3,4-trisphosphate = ADP + 1D-myo-inositol 1,3,4,6-tetrakisphosphate. GO:0035301 Hedgehog signaling complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035301 HSC|Hedgehog signalling complex A multiprotein complex that binds microtubules in a Hedgehog-dependent manner, and is required for signal transduction by members of the Hedgehog family of proteins. The core components of the complex are the serine/threonine protein kinase Fused, the kinesin motor protein Costal2 (Cos2), and a zinc finger transcription factor (Gli family members in humans, and Cubitus interruptus (Ci) in Drosophila). GO:0035302 ecdysteroid 25-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035302 Catalysis of the hydroxylation of an ecdysteroid at carbon position 25. Ecdysteroids are a group of polyhydroxylated ketosteroids which initiate post-embryonic development, particularly metamorphosis, in insects and other arthropods. GO:0035303 regulation of dephosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035303 Any process that modulates the frequency, rate or extent of removal of phosphate groups from a molecule. GO:0035304 regulation of protein dephosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035304 regulation of protein amino acid dephosphorylation Any process that modulates the frequency, rate or extent of removal of phosphate groups from a protein. GO:0035305 negative regulation of dephosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035305 inhibition of dephosphorylation|down regulation of dephosphorylation|downregulation of dephosphorylation|down-regulation of dephosphorylation Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a molecule. CHEBI:144503 5-deoxy-alpha-D-ribofuranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_144503 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001994 norepinephrine-epinephrine vasoconstriction during control of blood pressure|noradrenaline-adrenaline vasoconstriction involved in regulation of blood pressure|norepinephrine-epinephrine vasoconstriction during blood pressure regulation|norepinephrine-epinephrine vasoconstriction during blood pressure control A process that results in a decrease in the diameter of an artery during the norepinephrine-epinephrine response to decreased blood pressure. GO:0001995 norepinephrine-epinephrine catabolic process in blood stream biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001995 noradrenaline-adrenalin catabolic process in blood stream The chemical reactions and pathways resulting in the breakdown of norepinephrine or epinephrine in the bloodstream. GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001996 positive regulation of heart contraction rate by adrenaline-noradrenaline|positive control of heart contraction rate by epinephrine-norepinephrine|up regulation of heart contraction rate by epinephrine-norepinephrine|positive regulation of heart contraction rate by epinephrine-norepinephrine|increased chronotropy by epinephrine-norepinephrine|upregulation of heart contraction rate by epinephrine-norepinephrine|stimulation of heart contraction rate by epinephrine-norepinephrine|positive regulation of cardiac contraction rate by epinephrine-norepinephrine|up-regulation of heart contraction rate by epinephrine-norepinephrine|activation of heart contraction rate by epinephrine-norepinephrine The process in which the presence of epinephrine or norepinephrine in the bloodstream activates, maintains or increases the rate of heart contraction. GO:0001997 positive regulation of the force of heart contraction by epinephrine-norepinephrine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001997 positive regulation of heart contraction by adrenaline-noradrenaline|positive regulation of heart contraction by epinephrine-norepinephrine|increased inotropy by epinephrine-norepinephrine|increased strength of cardiac contraction by epinephrine-norepinephrine|increased force of heart contraction by adrenaline-noradrenaline|increased force of heart contraction by epinephrine-norepinephrine Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine in the bloodstream or released from the nerve endings. GO:0001990 regulation of systemic arterial blood pressure by hormone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001990 blood pressure regulation by hormone|hormonal control of blood pressure|hormonal regulation of blood pressure The process in which hormones modulate the force with which blood passes through the circulatory system. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action. GO:0001991 regulation of systemic arterial blood pressure by circulatory renin-angiotensin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001991 control of blood pressure by circulatory renin-angiotensin|circulatory renin-angiotensin blood pressure regulation|circulatory renin-angiotensin regulation of blood pressure|renin-angiotensin blood pressure control|circulatory renin-angiotensin control of blood pressure The process in which angiotensinogen metabolites in the bloodstream modulate the force with which blood passes through the circulatory system. The process begins when renin is released and cleaves angiotensinogen. GO:0001992 regulation of systemic arterial blood pressure by vasopressin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001992 blood pressure regulation by vasopressin|vasopressin control of blood pressure The regulation of blood pressure mediated by the signaling molecule vasopressin. Vasopressin is produced in the hypothalamus, and affects vasoconstriction, and renal water transport. GO:0001993 regulation of systemic arterial blood pressure by norepinephrine-epinephrine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001993 noradrenaline-adrenaline regulation of blood pressure|norepinephrine-epinephrine blood pressure regulation|norepinephrine-epinephrine blood pressure control The process in which the secretion of norepinephrine or epinephrine into the bloodstream modulates the force with which blood passes through the circulatory system. CHEBI:37493 1D-myo-inositol 5-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37493 GO:0001998 angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001998 angiotensin mediated vasoconstriction during control of blood pressure|angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure|angiotensin mediated vasoconstriction during blood pressure control|angiotensin mediated vasoconstriction during blood pressure regulation The decrease in blood vessel diameter as a result of the release of angiotensin into the blood stream. GO:0001999 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001999 renal response to blood flow during renin-angiotensin control of blood pressure The physiological response of the kidneys to a decrease in blood flow. CHEBI:37496 tetrahydroxyanthraquinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37496 GO:0001972 retinoic acid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001972 Interacting selectively and non-covalently with retinoic acid, 3,7-dimethyl-9-(2,6,-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid. GO:0001973 G protein-coupled adenosine receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001973 adenosine receptor signaling pathway|P1 receptor signaling pathway|adenosine receptor signaling pathway, G-protein coupled|adenosine receptor signalling pathway The series of molecular signals generated as a consequence of a receptor binding to extracellular adenosine and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity. GO:0001974 blood vessel remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001974 The reorganization or renovation of existing blood vessels. GO:0001975 response to amphetamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001975 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine. GO:0001970 positive regulation of activation of membrane attack complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001970 positive regulation of MAC assembly|stimulation of activation of membrane attack complex|up-regulation of activation of membrane attack complex|positive regulation of MAC formation|positive regulation of activation of TCC|upregulation of activation of membrane attack complex|positive regulation of activation of the terminal complement cascade|positive regulation of activation of terminal complement complex|positive regulation of membrane attack complex formation|positive regulation of membrane attack complex assembly|positive regulation of activation of MAC|up regulation of activation of membrane attack complex|activation of activation of membrane attack complex Any process that activates, maintains or increases the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade. GO:0001971 negative regulation of activation of membrane attack complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001971 down-regulation of activation of membrane attack complex|inhibition of activation of membrane attack complex|negative regulation of MAC formation|negative regulation of activation of TCC|negative regulation of membrane attack complex assembly|negative regulation of activation of the terminal complement cascade|down regulation of activation of membrane attack complex|negative regulation of activation of terminal complement complex|downregulation of activation of membrane attack complex|negative regulation of membrane attack complex formation|negative regulation of activation of MAC|negative regulation of MAC assembly Any process that stops, prevents, or reduces the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade. CHEBI:37470 trans-9,10-dihydrophenanthrene-9,10-diol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37470 GO:0001976 nervous system process involved in regulation of systemic arterial blood pressure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001976 blood pressure regulation by neurological process|fast control of arterial pressure|neurological system process involved in regulation of systemic arterial blood pressure|neurological process involved in regulation of systemic arterial blood pressure The regulation of blood pressure mediated by detection of stimuli and a neurological response. GO:0001977 renal system process involved in regulation of blood volume biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001977 renal blood volume control of blood pressure|renal regulation of blood volume A slow mechanism of blood pressure regulation that responds to changes in pressure resulting from fluid and salt intake by modulating the quantity of blood in the circulatory system. GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001978 baroreceptor pressure buffer system|baroreceptor feedback control of blood pressure|carotid sinus baroreceptor feedback regulation of systemic arterial blood pressure The process that modulates blood pressure by sensing the amount of stretch occurring in large arteries and responding to the input via central nervous system control. GO:0001979 regulation of systemic arterial blood pressure by chemoreceptor signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001979 chemoreceptor control of blood pressure|regulation of systemic arterial blood pressure by chemoreceptor signalling|chemoreceptor regulation of systemic arterial blood pressure The process that modulates blood pressure by the action of chemoreceptors found in the carotid and aortic bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions. GO:0001983 baroreceptor response to increased systemic arterial blood pressure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001983 The increase in nerve impulses from baroreceptors as a result of increased pressure on an artery that results in an inhibition of sympathetic nerve impulses to peripheral blood vessels. GO:0001984 artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001984 vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure An increase in the internal diameter of an artery, triggered by vasomotor suppression, during the chemoreceptor response to decreased blood pressure. GO:0001985 negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001985 down-regulation of heart contraction rate in baroreceptor response to increased blood pressure|negative regulation of heart contraction rate in baroreceptor response to increased blood pressure|inhibition of heart contraction rate in baroreceptor response to increased blood pressure|negative regulation of cardiac contraction rate in baroreceptor response to increased blood pressure|down regulation of heart contraction rate in baroreceptor response to increased blood pressure|downregulation of heart contraction rate in baroreceptor response to increased blood pressure|negative control of heart contraction rate in baroreceptor response to increased blood pressure Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction as a result of the baroreceptor response to increased blood pressure. GO:0001986 negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001986 decreased force of heart contraction during baroreceptor response to increased systemic arterial blood pressure|decreased strength of cardiac contraction during baroreceptor response to increased blood pressure Any process that decreases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the baroreceptor response to increased blood pressure. GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001980 CNS ischemic response|ischemic control of blood pressure|ischemic regulation of systemic arterial blood pressure The process that modulates blood pressure by the detection of carbon dioxide levels in the brain stem. Increased levels activate the sympathetic vasoconstrictor mechanism increasing the force with which blood flows through the circulatory system. GO:0001981 baroreceptor detection of arterial stretch biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001981 The series of events by which the change in diameter of an artery is detected and converted to a molecular signal. GO:0001982 baroreceptor response to decreased systemic arterial blood pressure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001982 The lowering of the number of nerve impulses from baroreceptors as a result of decreased stretch of an artery that results in an increased in sympathetic nerve impulses to peripheral blood vessels. CHEBI:37488 trihydroxyanthraquinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37488 CHEBI:13497 UDP-alpha-D-glucosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_13497 CHEBI:37483 monohydroxyanthraquinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37483 CHEBI:37480 D-galactopyranose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37480 CHEBI:37481 amidoalkyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37481 GO:0001987 vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001987 A process that is triggered by vasomotor excitation and results in a decrease in the diameter of an artery during the baroreceptor response to decreased blood pressure. GO:0001988 positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001988 up regulation of heart contraction rate in baroreceptor response to decreased blood pressure|activation of heart contraction rate in baroreceptor response to decreased blood pressure|stimulation of heart contraction rate in baroreceptor response to decreased blood pressure|positive control of heart contraction rate in baroreceptor response to decreased blood pressure|positive regulation of heart contraction rate in baroreceptor response to decreased blood pressure|positive regulation of cardiac contraction rate in baroreceptor response to decreased blood pressure|up-regulation of heart contraction rate in baroreceptor response to decreased blood pressure|upregulation of heart contraction rate in baroreceptor response to decreased blood pressure Any process that activates, maintains or increases the frequency, rate or extent of heart contraction as a result of the baroreceptor response to decreased blood pressure. GO:0001989 positive regulation of the force of heart contraction involved in baroreceptor response to decreased systemic arterial blood pressure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001989 increased force of heart contraction during baroreceptor response to decreased systemic arterial blood pressure|positive regulation of the force of heart contraction during baroreceptor response to decreased systemic arterial blood pressure|increased strength of cardiac contraction during baroreceptor response to decreased blood pressure Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as part of the baroreceptor response to decreased blood pressure. CHEBI:37484 dihydroxyanthraquinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37484 CHEBI:37485 hydroxyanthraquinones biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37485 GO:0001950 obsolete plasma membrane enriched fraction biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001950 PME fraction|plasma membrane enriched fraction OBSOLETE. The fraction of cells, prepared by disruptive biochemical methods, that is enriched for plasma membranes. GO:0001951 intestinal D-glucose absorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001951 Uptake of D-glucose into the blood by absorption from the small intestine. GO:0001952 regulation of cell-matrix adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001952 Any process that modulates the frequency, rate or extent of attachment of a cell to the extracellular matrix. GO:0001953 negative regulation of cell-matrix adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001953 down-regulation of cell-matrix adhesion|downregulation of cell-matrix adhesion|down regulation of cell-matrix adhesion|inhibition of cell-matrix adhesion Any process that stops, prevents, or reduces the rate or extent of cell adhesion to the extracellular matrix. CHEBI:37455 ribulose 5-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37455 GO:0001958 endochondral ossification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001958 Wikipedia:Endochondral_ossification Replacement ossification wherein bone tissue replaces cartilage. GO:0001959 regulation of cytokine-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001959 regulation of cytokine mediated signalling pathway|regulation of cytokine and chemokine mediated signaling pathway|regulation of cytokine mediated signaling pathway Any process that modulates the frequency, rate or extent of the cytokine mediated signaling pathway. CHEBI:37450 2-methoxyestrone 3-O-(beta-D-glucuronide) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37450 GO:0001954 positive regulation of cell-matrix adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001954 up-regulation of cell-matrix adhesion|activation of cell-matrix adhesion|up regulation of cell-matrix adhesion|upregulation of cell-matrix adhesion|stimulation of cell-matrix adhesion Any process that activates or increases the rate or extent of cell adhesion to an extracellular matrix. CHEBI:37453 phenanthrenediol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37453 GO:0001955 blood vessel maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001955 A developmental process, independent of morphogenetic (shape) change, that is required for a blood vessel to attain its fully functional state. GO:0001956 positive regulation of neurotransmitter secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001956 up regulation of neurotransmitter secretion|upregulation of neurotransmitter secretion|stimulation of neurotransmitter secretion|activation of neurotransmitter secretion|up-regulation of neurotransmitter secretion Any process that activates or increases the frequency, rate or extent of the regulated release of a neurotransmitter. GO:0001957 intramembranous ossification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001957 Wikipedia:Intramembranous_ossification dermal ossification|intramembranous bone ossification Direct ossification that occurs within mesenchyme or an accumulation of relatively unspecialized cells. GO:0001961 positive regulation of cytokine-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001961 positive regulation of cytokine mediated signalling pathway|up regulation of cytokine mediated signaling pathway|activation of cytokine mediated signaling pathway|stimulation of cytokine mediated signaling pathway|up-regulation of cytokine mediated signaling pathway|positive regulation of cytokine and chemokine mediated signaling pathway|upregulation of cytokine mediated signaling pathway|positive regulation of cytokine mediated signaling pathway Any process that activates or increases the frequency, rate or extent of a cytokine mediated signaling pathway. GO:0001962 alpha-1,3-galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001962 isoglobotriaosylceramide synthase Catalysis of the transfer of a galactose residue from a donor molecule, such as GDP-galactose or UDP-galactose, to an oligosaccharide, forming an alpha-(1->3) linkage. GO:0001963 synaptic transmission, dopaminergic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001963 dopaminergic synaptic transmission The vesicular release of dopamine. from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. GO:0001964 startle response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001964 Wikipedia:Startle_reaction An action or movement due to the application of a sudden unexpected stimulus. GO:0001960 negative regulation of cytokine-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001960 down regulation of cytokine mediated signaling pathway|negative regulation of cytokine mediated signaling pathway|downregulation of cytokine mediated signaling pathway|down-regulation of cytokine mediated signaling pathway|inhibition of cytokine mediated signaling pathway|negative regulation of cytokine and chemokine mediated signaling pathway|negative regulation of cytokine mediated signalling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the cytokine mediated signaling pathway. CHEBI:37469 9,10-dihydrophenanthrene-9,10-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37469 CHEBI:37466 O-phosphocorrinoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37466 GO:0001969 regulation of activation of membrane attack complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001969 regulation of activation of the terminal complement cascade|regulation of activation of terminal complement complex|regulation of membrane attack complex formation|regulation of activation of MAC|regulation of membrane attack complex assembly|regulation of MAC formation|regulation of activation of TCC|regulation of MAC assembly Any process that modulates the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade. GO:0001965 G-protein alpha-subunit binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001965 G-alpha protein subunit binding Interacting selectively and non-covalently with a G-protein alpha subunit. The alpha subunit binds a guanine nucleotide. CHEBI:37464 3,4-dihydrophenanthrene-3,4-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37464 GO:0001966 thigmotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001966 stereotaxis|taxis in response to touch stimulus|taxis in response to mechanical stimulus The directed movement of a motile cell or organism in response to touch. CHEBI:37465 (3R,4S)-3,4-dihydrophenanthrene-3,4-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37465 GO:0001967 suckling behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001967 nursing behavior Specific behavior of a newborn or infant mammal that results in the derivation of nourishment from the breast. CHEBI:37462 L-tagatose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37462 GO:0001968 fibronectin binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0001968 Interacting selectively and non-covalently with a fibronectin, a group of related adhesive glycoproteins of high molecular weight found on the surface of animal cells, connective tissue matrices, and in extracellular fluids. CHEBI:37463 ADP-D-ribose 2'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37463 GO:0098840 protein transport along microtubule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098840 microtubule-based protein transport The directed movement of a protein along a microtubule, mediated by motor proteins. GO:0098841 protein localization to cell division site after cytokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098841 A cellular protein localization process in which a protein is transported to, or maintained at, the site of cell division following cytokinesis. GO:1902658 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902658 GO:1902659 regulation of glucose mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902659 regulation of glucose mediated signalling Any process that modulates the frequency, rate or extent of glucose mediated signaling pathway. GO:1902656 calcium ion import into cytosol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902656 calcium import into cytosol The directed movement of calcium ion into a cytosol. GO:1902657 protein localization to prospore membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902657 protein localisation to prospore membrane|establishment of protein localisation to prospore membrane|protein targeting to FSM|protein targeting to prospore membrane|protein targeting to forespore membrane|establishment of protein localization to prospore membrane|protein localization in prospore membrane|protein-prospore membrane targeting|establishment of protein localization in prospore membrane|protein localisation in prospore membrane|establishment of protein localisation in prospore membrane|protein targeting to ascospore-type prospore membrane A process in which a protein is transported to, or maintained in, a location within a prospore membrane. GO:1902654 aromatic primary alcohol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902654 aromatic primary alcohol metabolism The chemical reactions and pathways involving aromatic primary alcohol. GO:1902655 aromatic primary alcohol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902655 aromatic primary alcohol anabolism|aromatic primary alcohol synthesis|aromatic primary alcohol biosynthesis|aromatic primary alcohol formation The chemical reactions and pathways resulting in the formation of aromatic primary alcohol. GO:1902652 secondary alcohol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902652 secondary alcohol metabolism The chemical reactions and pathways involving secondary alcohol. GO:1902653 secondary alcohol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902653 secondary alcohol synthesis|secondary alcohol formation|secondary alcohol biosynthesis|secondary alcohol anabolism The chemical reactions and pathways resulting in the formation of secondary alcohol. GO:1902650 negative regulation of histone H2A-H2B dimer displacement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902650 downregulation of histone H2A-H2B dimer displacement|down regulation of histone H2A-H2B dimer displacement|inhibition of histone H2A-H2B dimer displacement|down-regulation of histone H2A-H2B dimer displacement Any process that stops, prevents or reduces the frequency, rate or extent of histone H2A-H2B dimer displacement. GO:0060230 lipoprotein lipase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0060230 Binds to and increases the activity of a lipoprotein lipase, an enzyme that catalyzes of the hydrolysis of a lipid within a lipoprotein. GO:1902651 positive regulation of histone H2A-H2B dimer displacement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902651 up regulation of histone H2A-H2B dimer displacement|upregulation of histone H2A-H2B dimer displacement|up-regulation of histone H2A-H2B dimer displacement|activation of histone H2A-H2B dimer displacement Any process that activates or increases the frequency, rate or extent of histone H2A-H2B dimer displacement. GO:0060231 mesenchymal to epithelial transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060231 epithelial cell differentiation from mesenchymal cell|mesenchymal-epithelial transition A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell. GO:0060232 delamination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060232 The process of negative regulation of cell adhesion that results in a cell or sheet of cells splitting off from an existing epithelial sheet. GO:0035265 organ growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035265 The increase in size or mass of an organ. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that function together as to perform a specific function. GO:1902660 negative regulation of glucose mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902660 down-regulation of glucose mediated signaling pathway|down-regulation of glucose mediated signalling|negative regulation of glucose mediated signalling|downregulation of glucose mediated signaling pathway|inhibition of glucose mediated signalling|down regulation of glucose mediated signaling pathway|inhibition of glucose mediated signaling pathway|down regulation of glucose mediated signalling|downregulation of glucose mediated signalling Any process that stops, prevents or reduces the frequency, rate or extent of glucose mediated signaling pathway. GO:0060233 oenocyte delamination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060233 The negative regulation of cell adhesion process in which an oenocyte splits off of an existing epithelial sheet. GO:0035266 meristem growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035266 The increase in size or mass of a meristem, a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation. GO:0035267 NuA4 histone acetyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035267 TIP60 histone acetylase complex|TIP60 histone acetyltransferase complex A complex having histone acetylase activity on chromatin, as well as ATPase, DNA helicase and structural DNA binding activities. The complex is thought to be involved in double-strand DNA break repair. Subunits of the human complex include HTATIP/TIP60, TRRAP, RUVBL1, BUVBL2, beta-actin and BAF53/ACTL6A. In yeast, the complex has 13 subunits, including the catalytic subunit Esa1 (homologous to human Tip60). GO:0060234 neuroblast delamination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060234 The negative regulation of cell adhesion process in which a neuroblast splits off of a neurectodermal sheet. GO:0035268 protein mannosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035268 protein amino acid mannosylation The addition of a mannose residue to a protein acceptor molecule. GO:0060235 lens induction in camera-type eye biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060235 Signaling at short range between the head ectoderm and the optic vesicle that results in the head ectoderm forming a lens. GO:0035269 protein O-linked mannosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035269 protein amino acid O-linked mannosylation The transfer of mannose from dolichyl activated mannose to the hydroxyl group of a seryl or threonyl residue of a protein acceptor molecule, to form an O-linked protein-sugar linkage. GO:0060236 regulation of mitotic spindle organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060236 regulation of mitotic spindle organisation|regulation of mitotic spindle organization and biogenesis Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle. GO:0060237 regulation of fungal-type cell wall organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060237 regulation of fungal-type cell wall organization and biogenesis|regulation of fungal-type cell wall organisation Any process that modulates the rate, frequency or extent of the formation, arrangement of constituent parts, or disassembly of the fungal-type cell wall. GO:0060238 regulation of signal transduction involved in conjugation with cellular fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060238 Any process that modulates the rate, frequency or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, the series of molecular signals that bring about the relay, amplification or dampening of a signal generated in response to a cue, such as starvation or pheromone exposure, in organisms that undergo conjugation with cellular fusion. GO:0060239 positive regulation of signal transduction involved in conjugation with cellular fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060239 Any process that increases the rate, frequency or extent of the series of molecular signals that bring about the relay, amplification or dampening of a signal generated in response to a cue, such as starvation or pheromone exposure, in organisms that undergo conjugation with cellular fusion. GO:0098848 alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098848 RHEA:34707|EC:4.7.1.1 alpha-D-ribose-1-methylphosphonate-5-phosphate C-P-lyase (methane forming) Catalysis of the reaction: alpha-D-ribose 1-methylphosphonate 5-phosphate = alpha-D-ribose 1,2-cyclic phosphate 5-phosphate + methane. GO:0098849 cellular detoxification of cadmium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098849 Any process that reduces or removes the toxicity of cadmium cations in a cell. These include transport of cadmium cations away from sensitive areas and to compartments or complexes whose purpose is sequestration. GO:0098846 podocyte foot biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098846 Wikipedia:Podocyte secondary podocyte projection|podocyte foot process|pedicel A cell projection of a podocyte (glomerular visceral epithelial cell) forming a foot-like structure projecting from a podocyte primary projection, that wraps around capillaries of a renal glomerulus. Adjacent feet (pedicels) interdigitate, leaving thin filtration slits between them, which are covered by slit diaphragms. GO:0098847 sequence-specific single stranded DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098847 Interacting selectively and non-covalently with single-stranded DNA of a specific nucleotide composition. GO:0035260 internal genitalia morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035260 The process in which the anatomical structures of the internal genitalia are generated and organized. The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals. GO:0035261 external genitalia morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035261 The process in which the anatomical structures of the external genitalia are generated and organized. The external genitalia are the outer sex organs, such as the penis or vulva in mammals. GO:0098844 postsynaptic endocytic zone membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098844 The region of the postsynaptic membrane that is part of the postsynaptic endocytic zone. This region of membrane is associated with stable clathrin puncta. GO:0035262 gonad morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035262 The process in which the anatomical structures of the gonads are generated and organized. A gonad is an animal organ producing gametes, e.g. the testes or the ovary in mammals. GO:0098845 postsynaptic endosome biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098845 An endosomal compartment that is part of the post-synapse. Only early and recycling endosomes are typically present in the postsynapse. GO:0035263 genital disc sexually dimorphic development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035263 The sex-specific patterns of primoridia growth and differentiation in the genital imaginal disc. The anal primordium of the genital disc develops in both sexes, but depending on the genetic sex gives rise to either male or female analia. Depending on the genetic sex, only one of the two genital primordia develop. In females the female genital primordium develops and gives rise to the female genitalia whereas the male primordium is repressed. Conversely, in males the male genital primordium develops and gives rise to the male genitalia whereas the female genital primordium is repressed. GO:0098842 postsynaptic early endosome biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098842 An early endosome of the postsynapse. It acts as the major sorting station on the endocytic pathway, targeting neurotransmitter receptors for degregation or recycling. GO:0035264 multicellular organism growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035264 body growth The increase in size or mass of an entire multicellular organism, as opposed to cell growth. GO:0098843 postsynaptic endocytic zone biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098843 A stably positioned site of clathrin adjacent and physically attached to the postsynaptic specialization, which is the site of endocytosis of post-synaptic proteins. GO:0098851 double-stranded miRNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098851 miRNA duplex binding Interacting selectively and non-covalently with double-stranded miRNA. double-stranded miRNA is formed by processing of pre-miRNA stem-loop structures. GO:0098852 lytic vacuole membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098852 The lipid bilayer surrounding a lytic vacuole and separating its contents from the cytoplasm of the cell. GO:0098850 extrinsic component of synaptic vesicle membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098850 The component of the synaptic vesicle membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:1902669 positive regulation of axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902669 upregulation of axon pathfinding|activation of axon guidance|up-regulation of axon growth cone guidance|up regulation of axon chemotaxis|up-regulation of axon pathfinding|activation of axon pathfinding|positive regulation of axon chemotaxis|upregulation of axon growth cone guidance|up-regulation of axon guidance|activation of axon chemotaxis|positive regulation of axon pathfinding|upregulation of axon guidance|up-regulation of axon chemotaxis|up regulation of axon growth cone guidance|up regulation of axon pathfinding|positive regulation of axon growth cone guidance|activation of axon growth cone guidance|up regulation of axon guidance|upregulation of axon chemotaxis Any process that activates or increases the frequency, rate or extent of axon guidance. GO:2001204 regulation of osteoclast development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001204 regulation of osteoclast cell development Any process that modulates the frequency, rate or extent of osteoclast development. GO:1902667 regulation of axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902667 regulation of axon chemotaxis|regulation of axon growth cone guidance|regulation of axon pathfinding Any process that modulates the frequency, rate or extent of axon guidance. GO:2001205 negative regulation of osteoclast development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001205 negative regulation of osteoclast cell development Any process that stops, prevents or reduces the frequency, rate or extent of osteoclast development. GO:1902668 negative regulation of axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902668 down regulation of axon chemotaxis|down-regulation of axon guidance|downregulation of axon chemotaxis|inhibition of axon growth cone guidance|inhibition of axon guidance|negative regulation of axon chemotaxis|down regulation of axon growth cone guidance|down-regulation of axon chemotaxis|negative regulation of axon pathfinding|down-regulation of axon pathfinding|downregulation of axon growth cone guidance|down regulation of axon guidance|downregulation of axon pathfinding|inhibition of axon chemotaxis|downregulation of axon guidance|down-regulation of axon growth cone guidance|negative regulation of axon growth cone guidance|down regulation of axon pathfinding|inhibition of axon pathfinding Any process that stops, prevents or reduces the frequency, rate or extent of axon guidance. GO:1902665 response to isobutanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902665 process resulting in tolerance to isobutanol|response to 2-methylpropan-1-ol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isobutanol stimulus. GO:2001206 positive regulation of osteoclast development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001206 positive regulation of osteoclast cell development Any process that activates or increases the frequency, rate or extent of osteoclast development. GO:1902666 obsolete protein localization to Mmi1 nuclear focus complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902666 protein localization in Mmi1 nuclear focus complex|protein localisation to Mmi1 nuclear focus complex|protein localisation in Mmi1 nuclear focus complex OBSOLETE. A process in which a protein is transported to, or maintained in, a location within a Mmi1 nuclear focus complex. GO:2001207 regulation of transcription elongation from RNA polymerase I promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001207 regulation of RNA elongation from Pol I promoter Any process that modulates the frequency, rate or extent of transcription elongation from RNA polymerase I promoter. GO:1902663 negative regulation of peptidyl-L-cysteine S-palmitoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902663 inhibition of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|downregulation of peptidyl-L-cysteine S-palmitoylation|down regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|downregulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|down regulation of peptidyl-cysteine S-palmitoylation|inhibition of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|down regulation of peptidyl-L-cysteine S-palmitoylation|inhibition of peptidyl-cysteine S-palmitoylation|inhibition of peptidyl-L-cysteine S-palmitoylation|down regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|down regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|inhibition of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|downregulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|negative regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|down-regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|down-regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|negative regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|negative regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|down-regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|down-regulation of peptidyl-cysteine S-palmitoylation|negative regulation of peptidyl-cysteine S-palmitoylation|down-regulation of peptidyl-L-cysteine S-palmitoylation|negative regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|inhibition of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|down-regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|downregulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|downregulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|downregulation of peptidyl-cysteine S-palmitoylation|down regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-L-cysteine S-palmitoylation. GO:2001208 negative regulation of transcription elongation by RNA polymerase I biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001208 negative regulation of RNA elongation from Pol I promoter|negative regulation of transcription elongation from RNA polymerase I promoter Any process that stops, prevents or reduces the frequency, rate or extent of transcription elongation mediated by RNA polymerase I. GO:1902664 positive regulation of peptidyl-L-cysteine S-palmitoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902664 upregulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|upregulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|upregulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|upregulation of peptidyl-cysteine S-palmitoylation|upregulation of peptidyl-L-cysteine S-palmitoylation|upregulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|up-regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|activation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|up regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|up-regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|activation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|up-regulation of peptidyl-cysteine S-palmitoylation|activation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|positive regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|up-regulation of peptidyl-L-cysteine S-palmitoylation|activation of peptidyl-cysteine S-palmitoylation|activation of peptidyl-L-cysteine S-palmitoylation|up-regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|activation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|positive regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|up regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|positive regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|positive regulation of peptidyl-cysteine S-palmitoylation|up-regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|up regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|up regulation of peptidyl-cysteine S-palmitoylation|up regulation of peptidyl-L-cysteine S-palmitoylation|positive regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|up regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine Any process that activates or increases the frequency, rate or extent of peptidyl-L-cysteine S-palmitoylation. GO:2001209 positive regulation of transcription elongation from RNA polymerase I promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001209 positive regulation of RNA elongation from Pol I promoter Any process that activates or increases the frequency, rate or extent of transcription elongation from RNA polymerase I promoter. GO:1902661 positive regulation of glucose mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902661 up regulation of glucose mediated signalling|activation of glucose mediated signalling|positive regulation of glucose mediated signalling|up regulation of glucose mediated signaling pathway|up-regulation of glucose mediated signalling|upregulation of glucose mediated signaling pathway|upregulation of glucose mediated signalling|up-regulation of glucose mediated signaling pathway|activation of glucose mediated signaling pathway Any process that activates or increases the frequency, rate or extent of glucose mediated signaling pathway. GO:1902662 regulation of peptidyl-L-cysteine S-palmitoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902662 regulation of peptidyl-cysteine S-palmitoylation|regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine Any process that modulates the frequency, rate or extent of peptidyl-L-cysteine S-palmitoylation. GO:0060220 camera-type eye photoreceptor cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060220 The process in which the developmental fate of a cell becomes restricted such that it will develop into a photoreceptor cell in a camera-type eye. GO:0035254 glutamate receptor binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0035254 Interacting selectively and non-covalently with a glutamate receptor. GO:0060221 retinal rod cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060221 The process in which a relatively unspecialized cell acquires the specialized features of a retinal rod cell. GO:1902670 carbon dioxide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1902670 CO2 binding Interacting selectively and non-covalently with carbon dioxide. GO:0035255 ionotropic glutamate receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035255 Interacting selectively and non-covalently with an ionotropic glutamate receptor. Ionotropic glutamate receptors bind glutamate and exert an effect through the regulation of ion channels. GO:1902671 left anterior basal body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902671 ciliary basal body of left anterior cilium|cilium basal body of left anterior flagellum|left anterior flagellum ciliary basal body|cilial basal body of left anterior cilium|microtubule basal body of left anterior flagellum|microtubule basal body of left anterior cilium|cilial basal body of left anterior flagellum|ciliary basal body of left anterior flagellum|cilium basal body of left anterior cilium Any ciliary basal body that is part of a left anterior flagellum found in Giardia species (trophozoite stage). GO:0060222 regulation of retinal cone cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060222 Any process that modulates the process in which a cell becomes committed to a retinal cone cell fate. Retinal cone cell fate commitment is the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell. GO:0035256 G protein-coupled glutamate receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035256 metabotropic glutamate receptor binding|G-protein coupled glutamate receptor binding Interacting selectively and non-covalently with a G protein-coupled glutamate receptor (a metabotropic glutamate receptor). GO:0060223 retinal rod cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060223 The process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye. GO:0060224 regulation of retinal rod cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060224 Any process that modulates the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye. GO:0035257 nuclear hormone receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035257 Interacting selectively and non-covalently with a nuclear hormone receptor, a ligand-dependent receptor found in the nucleus of the cell. GO:0035258 steroid hormone receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035258 Interacting selectively and non-covalently with a steroid hormone receptor. GO:2001200 positive regulation of dendritic cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001200 Any process that activates or increases the frequency, rate or extent of dendritic cell differentiation. GO:0060225 positive regulation of retinal rod cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060225 Any process that increases the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye. GO:2001201 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2001201 GO:0035259 glucocorticoid receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035259 Interacting selectively and non-covalently with a glucocorticoid receptor. GO:0060226 negative regulation of retinal cone cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060226 Any process that increases the process in which a cell becomes committed to a retinal cone cell fate. Retinal cone cell fate commitment is the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell. GO:0060227 Notch signaling pathway involved in camera-type eye photoreceptor fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060227 Notch signalling pathway involved in camera-type eye photoreceptor fate commitment The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the commitment of a precursor cell to a eye photoreceptor fate. GO:2001202 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2001202 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0060228 LCAT activator activity Increases the activity of phosphatidylcholine-sterol O-acyltransferase, an enzyme that converts cholesterol and phosphatidylcholine (lecithins) to cholesteryl esters and lyso-phosphatidylcholines. GO:2001203 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2001203 GO:0098859 actin filament bundle of actin-based cell projection biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098859 A bundle of cross-linked actin filaments that is part of an actin-based cell protrusion, in which filaments are oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex which stabilizes the filaments. GO:0060229 lipase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0060229 Binds to and increases the activity of a lipase, an enzyme that catalyzes of the hydrolysis of a lipid. GO:0098857 membrane microdomain biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098857 A membrane region with a lipid composition that is distinct from that of the membrane regions that surround it. GO:0098858 actin-based cell projection biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098858 A cell projection supported by an assembly of actin filaments, and which lacks microtubules. GO:0035250 UDP-galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035250 Catalysis of the transfer of a galactose group from UDP-galactose to an acceptor molecule. GO:0098855 HCN channel complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098855 K/Na hyperpolarization-activated cyclic nucleotide-gated channel complex|potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 tetramer|potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 tetramer|potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel complex|K/Na hyperpolarization-activated cyclic nucleotide-gated channel 4 complex|K/Na hyperpolarization-activated cyclic nucleotide-gated channel 2 complex|K/Na hyperpolarization-activated cyclic nucleotide-gated channel 1 complex|HCN4 channel complex|HCN3 channel complex|K/Na hyperpolarization-activated channel 3 complex|potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 complex|HCN2 channel complex|HCN1 channel complex|potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 complex|potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 complex|potassium/sodium hyperpolarization-activated channel 3 complex A cation ion channel with a preference for K+ over Na+ ions, which is activated by membrane hyperpolarization, and consists of a tetramer of HCN family members. Some members of this family (HCN1, HCN2 and HCN4) are also activated when cAMP binds to their cyclic nucleotide binding domain (CNBD). Channel complexes of this family play an important role in the control of pacemaker activity in the heart. GO:0098856 intestinal lipid absorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098856 Any process in which lipids are taken up from the contents of the intestine. GO:0035251 UDP-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035251 Reactome:R-HSA-1912353|MetaCyc:PHENOL-BETA-GLUCOSYLTRANSFERASE-RXN Catalysis of the transfer of a glucosyl group from UDP-glucose to an acceptor molecule. GO:0035252 UDP-xylosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035252 Reactome:R-HSA-5617138|Reactome:R-HSA-9638090|Reactome:R-HSA-6785668 Catalysis of the transfer of a xylosyl group from UDP-xylose to an acceptor molecule. GO:0098853 endoplasmic reticulum-vacuole membrane contact site biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098853 endoplasmic reticulum-vacuole membrane contact site|ER-vacuole membrane contact site A zone of apposition between endoplasmic-reticulum and lytic vacuole membranes, structured by bridging complexes. GO:0035253 ciliary rootlet biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035253 cilium rootlet|cilial rootlet A cytoskeleton-like structure, originating from the basal body at the proximal end of a cilium, and extending proximally toward the cell nucleus. Rootlets are typically 80-100 nm in diameter and contain cross striae distributed at regular intervals of approximately 55-70 nm. GO:0098854 podocyte primary projection biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098854 glomerular visceral epithelial cell primary projection|primary podocyte process|podocyte major process A cell projection originating from a renal glomerular podocyte and extending to the renal glomerular podocyte foot. GO:1902678 right caudal basal body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902678 ciliary basal body of right caudal flagellum|cilium basal body of right caudal cilium|cilial basal body of right caudal flagellum|microtubule basal body of right caudal flagellum|microtubule basal body of right caudal cilium|cilial basal body of right caudal cilium|right caudal flagellum ciliary basal body|cilium basal body of right caudal flagellum|ciliary basal body of right caudal cilium Any ciliary basal body that is part of a right caudal flagellum found in Giardia species (trophozoite stage). GO:2001215 regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001215 regulation of HMG-CoA reductase activity|regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity Any process that modulates the frequency, rate or extent of hydroxymethylglutaryl-CoA reductase (NADPH) activity. GO:1902679 negative regulation of RNA biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902679 inhibition of RNA biosynthetic process|inhibition of RNA biosynthesis|inhibition of RNA synthesis|inhibition of RNA formation|down regulation of RNA anabolism|downregulation of RNA anabolism|down regulation of RNA synthesis|negative regulation of RNA biosynthesis|down-regulation of RNA biosynthesis|down regulation of RNA formation|down-regulation of RNA biosynthetic process|downregulation of RNA synthesis|downregulation of RNA formation|down-regulation of RNA anabolism|negative regulation of RNA anabolism|downregulation of RNA biosynthesis|downregulation of RNA biosynthetic process|down-regulation of RNA synthesis|negative regulation of RNA synthesis|down regulation of RNA biosynthesis|down regulation of RNA biosynthetic process|down-regulation of RNA formation|inhibition of RNA anabolism|negative regulation of RNA formation Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process. GO:2001216 negative regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001216 negative regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity|negative regulation of HMG-CoA reductase activity Any process that stops, prevents or reduces the frequency, rate or extent of hydroxymethylglutaryl-CoA reductase (NADPH) activity. GO:1902676 right ventral basal body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902676 cilial basal body of right ventral cilium|microtubule basal body of right ventral cilium|ciliary basal body of right ventral flagellum|cilium basal body of right ventral cilium|cilium basal body of right ventral flagellum|ciliary basal body of right ventral cilium|microtubule basal body of right ventral flagellum|right ventral flagellum ciliary basal body|cilial basal body of right ventral flagellum Any ciliary basal body that is part of a right ventral flagellum found in Giardia species (trophozoite stage). GO:2001217 obsolete regulation of S/G2 transition of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001217 regulation of S/G2 transition of mitotic cell cycle OBSOLETE. Any process that modulates the frequency, rate or extent of S/G2 transition of mitotic cell cycle. GO:1902677 left caudal basal body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902677 ciliary basal body of left caudal cilium|cilium basal body of left caudal flagellum|left caudal flagellum ciliary basal body|cilial basal body of left caudal cilium|microtubule basal body of left caudal flagellum|microtubule basal body of left caudal cilium|cilial basal body of left caudal flagellum|ciliary basal body of left caudal flagellum|cilium basal body of left caudal cilium Any ciliary basal body that is part of a left caudal flagellum found in Giardia species (trophozoite stage). GO:2001218 obsolete negative regulation of S/G2 transition of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001218 negative regulation of S/G2 transition of mitotic cell cycle OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of S/G2 transition of mitotic cell cycle. GO:1902674 right posteriolateral basal body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902674 cilial basal body of right posteriolateral flagellum|cilium basal body of right posterolateral cilium|ciliary basal body of right posterolateral flagellum|cilium basal body of right posteriolateral cilium|ciliary basal body of right posteriolateral flagellum|cilial basal body of right posterolateral flagellum|microtubule basal body of right posterolateral cilium|microtubule basal body of right posterolateral flagellum|cilial basal body of right posterolateral cilium|ciliary basal body of right posteriolateral cilium|cilium basal body of right posteriolateral flagellum|right posteriolateral flagellum ciliary basal body|cilium basal body of right posterolateral flagellum|ciliary basal body of right posterolateral cilium|cilial basal body of right posteriolateral cilium|microtubule basal body of right posteriolateral cilium|microtubule basal body of right posteriolateral flagellum Any ciliary basal body that is part of a right posteriolateral flagellum found in Giardia species (trophozoite stage). GO:2001219 obsolete positive regulation of S/G2 transition of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001219 positive regulation of S/G2 transition of mitotic cell cycle OBSOLETE. Any process that activates or increases the frequency, rate or extent of S/G2 transition of mitotic cell cycle. GO:0060250 germ-line stem-cell niche homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060250 maintenance of germ line stem cell niche|germ-line stem-cell niche maintenance|maintenance of germ-line stem-cell niche|maintenance of germ-line stem cell niche|maintenance of germ line stem-cell niche A homeostatic process involved in the maintenance of an internal steady state within the germ-line stem-cell niche. This includes control of cellular proliferation and death and control of metabolic function that allows the niche to continue to function. A gem-line stem-cell niche is an anatomical structure that regulates how germ-line stem-cells are used and saves them from depletion. GO:1902675 left ventral basal body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902675 microtubule basal body of left ventral cilium|cilium basal body of left ventral flagellum|cilial basal body of left ventral cilium|left ventral flagellum ciliary basal body|ciliary basal body of left ventral flagellum|ciliary basal body of left ventral cilium|cilial basal body of left ventral flagellum|cilium basal body of left ventral cilium|microtubule basal body of left ventral flagellum Any ciliary basal body that is part of a left ventral flagellum found in Giardia species (trophozoite stage). GO:0060251 regulation of glial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060251 Any process that modulates the frequency, rate or extent of glial cell proliferation. GO:1902672 right anterior basal body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902672 cilium basal body of right anterior cilium|cilial basal body of right anterior flagellum|microtubule basal body of right anterior flagellum|microtubule basal body of right anterior cilium|cilial basal body of right anterior cilium|right anterior flagellum ciliary basal body|cilium basal body of right anterior flagellum|ciliary basal body of right anterior cilium|ciliary basal body of right anterior flagellum Any ciliary basal body that is part of a right anterior flagellum found in Giardia species (trophozoite stage). GO:0060252 positive regulation of glial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060252 Any process that activates or increases the rate or extent of glial cell proliferation. GO:1902673 left posteriolateral basal body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902673 ciliary basal body of left posterolateral cilium|cilial basal body of left posteriolateral cilium|left posteriolateral flagellum ciliary basal body|cilium basal body of left posterolateral flagellum|cilium basal body of left posteriolateral flagellum|cilial basal body of left posterolateral cilium|ciliary basal body of left posteriolateral cilium|microtubule basal body of left posterolateral cilium|microtubule basal body of left posterolateral flagellum|ciliary basal body of left posteriolateral flagellum|cilial basal body of left posterolateral flagellum|cilium basal body of left posteriolateral cilium|cilium basal body of left posterolateral cilium|cilial basal body of left posteriolateral flagellum|ciliary basal body of left posterolateral flagellum|microtubule basal body of left posteriolateral flagellum|microtubule basal body of left posteriolateral cilium Any ciliary basal body that is part of a left posteriolateral flagellum found in Giardia species (trophozoite stage). GO:0060253 negative regulation of glial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060253 Any process that stops or decreases the rate or extent of glial cell proliferation. GO:0035243 protein-arginine omega-N symmetric methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035243 Reactome:R-HSA-6804383|RESID:AA0069|RESID:AA0067|EC:2.1.1.320|RHEA:48108 type II PRMT activity|type II protein arginine methyltransferase activity|S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-Nomega,Nomega'-dimethyl-L-arginine-forming) Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the terminal nitrogen (omega nitrogen) residue that is not already methylated, resulting in symmetrical peptidyl-N(omega),N'(omega)-dimethyled arginine residues. GO:0060254 regulation of N-terminal protein palmitoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060254 Any process that modulates the rate frequency or extent of the covalent attachment of a palmitoyl group to the N-terminal amino acid residue of a protein. GO:1902681 regulation of replication fork arrest at rDNA repeats biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902681 regulation of replication fork arrest at ribosomal DNA repeats|regulation of replication fork blocking at rDNA repeats Any process that modulates the frequency, rate or extent of replication fork arrest at rDNA repeats. GO:0060255 regulation of macromolecule metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060255 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. GO:1902682 protein localization to pericentric heterochromatin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902682 protein localization to pericentric heterochromatin|protein localisation in centromeric heterochromatin A process in which a protein is transported to, or maintained in the pericentric heterochromatin. GO:0035244 peptidyl-arginine C-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035244 Catalysis of the transfer of a methyl group to the carbon atom of an arginine residue in a protein. GO:0060256 regulation of flocculation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060256 regulation of flocculation via cell wall protein-carbohydrate interaction Any process that modulates the rate, frequency or extent of the non-sexual aggregation of single-celled organisms. GO:0035245 peptidyl-arginine C-methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035245 The addition of a methyl group onto a carbon atom of an arginine residue in a protein. GO:2001210 regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001210 regulation of acetate-mevalonate pathway|regulation of Ac-MVA pathway|regulation of isopentenyl diphosphate anabolism, mevalonate pathway|regulation of isopentenyl diphosphate synthesis, mevalonate pathway|regulation of isopentenyl diphosphate formation, mevalonate pathway Any process that modulates the frequency, rate or extent of isopentenyl diphosphate biosynthetic process, mevalonate pathway. GO:1902680 positive regulation of RNA biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902680 up regulation of RNA biosynthesis|up regulation of RNA biosynthetic process|activation of RNA synthesis|positive regulation of RNA synthesis|up regulation of RNA formation|activation of RNA formation|positive regulation of RNA formation|up-regulation of RNA anabolism|upregulation of RNA biosynthesis|upregulation of RNA biosynthetic process|up-regulation of RNA synthesis|up-regulation of RNA formation|upregulation of RNA anabolism|up-regulation of RNA biosynthesis|up-regulation of RNA biosynthetic process|upregulation of RNA synthesis|activation of RNA biosynthesis|activation of RNA biosynthetic process|upregulation of RNA formation|up regulation of RNA anabolism|activation of RNA anabolism|positive regulation of RNA anabolism|up regulation of RNA synthesis|positive regulation of RNA biosynthesis Any process that activates or increases the frequency, rate or extent of RNA biosynthetic process. GO:0060257 negative regulation of flocculation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060257 negative regulation of coflocculation Any process that decreases the rate, frequency or extent of the non-sexual aggregation of single-celled organisms. GO:0035246 peptidyl-arginine N-methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035246 The addition of a methyl group onto a nitrogen atom of an arginine residue in a protein. GO:2001211 negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001211 negative regulation of isopentenyl diphosphate synthesis, mevalonate pathway|negative regulation of isopentenyl diphosphate formation, mevalonate pathway|negative regulation of acetate-mevalonate pathway|negative regulation of isopentenyl diphosphate anabolism, mevalonate pathway|negative regulation of Ac-MVA pathway Any process that stops, prevents or reduces the frequency, rate or extent of isopentenyl diphosphate biosynthetic process, mevalonate pathway. GO:0035247 peptidyl-arginine omega-N-methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035247 RESID:AA0069|RESID:AA0068|RESID:AA0067 The addition of a methyl group onto a terminal nitrogen (omega nitrogen) atom of an arginine residue in a protein. GO:0060258 negative regulation of filamentous growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060258 Any process that decreases the frequency, rate or extent of the process in which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape. GO:2001212 regulation of vasculogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001212 regulation of vascular morphogenesis Any process that modulates the frequency, rate or extent of vasculogenesis. GO:0060259 regulation of feeding behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060259 regulation of feeding behaviour Any process that modulates the rate, frequency or extent of the behavior associated with the intake of food. GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035248 alpha-1,4-GalNAc transferase activity Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an acceptor molecule, forming an alpha-1,4 linkage. GO:0035249 synaptic transmission, glutamatergic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035249 glutamatergic synaptic transmission The vesicular release of glutamate from a presynapse, across a chemical synapse, the subsequent activation of glutamate receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. GO:2001213 negative regulation of vasculogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001213 negative regulation of vascular morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of vasculogenesis. GO:0098828 modulation of inhibitory postsynaptic potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098828 regulation of inhibitory postsynaptic potential Any process that modulates the frequency, rate or extent of inhibitory postsynaptic potential (IPSP). IPSP is a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential. GO:2001214 positive regulation of vasculogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001214 positive regulation of vascular morphogenesis Any process that activates or increases the frequency, rate or extent of vasculogenesis. GO:0098829 intestinal folate absorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098829 Uptake of folic into the blood by absorption from the small intestine. GO:0098826 endoplasmic reticulum tubular network membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098826 The membrane of the endoplasmic reticulum tubular network. GO:0098827 endoplasmic reticulum subcompartment biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098827 A distinct region of the endoplasmic reticulum. PO:0000191 synergid biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000191 助細胞 (Japanese, exact)|sinérgida (Spanish, exact) Cell, usually two in number, in the micropylar end of the embryo sac of angiosperms associated with the egg in the egg apparatus. GO:0098824 peptidyl-cysteine sulfation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098824 RESID:AA0171 The sulfation of peptidyl-cysteine to form S-sulfo-L-cysteine. GO:0098825 peptidyl-histidine guanylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098825 RESID:AA0325 The guanylylation of peptidyl-histidine to form (phospho-5'-guanosine)-L-histidine. GO:0098822 peptidyl-cysteine modification to L-cysteine persulfide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098822 RESID:AA0269 The modification of peptidyl-cysteine to form peptidyl-L-cysteine persulfide. GO:0098823 peptidyl-cysteine modification to S-amindino-L-cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098823 RESID:AA0335 The amidinylation of peptidyl-cysteine to form peptidyl-S-amidino-L-cysteine. GO:0035240 dopamine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035240 Interacting selectively and non-covalently with dopamine, a catecholamine neurotransmitter formed by aromatic-L-amino-acid decarboxylase from 3,4-dihydroxy-L-phenylalanine. GO:0035241 protein-arginine omega-N monomethyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035241 RHEA:48100|RESID:AA0069|EC:2.1.1.321 S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-Nomega-methyl-L-arginine-forming)|type III protein arginine methyltransferase activity Catalysis of the addition of a methyl group to either of the unmethylated terminal nitrogen atoms (also called omega nitrogen) in peptidyl-arginine to form an omega-N-G-monomethylated arginine residue. The reaction is S-adenosyl-L-methionine + [protein]-L-arginine = S-adenosyl-L-homocysteine + [protein]-Nomega-methyl-L-arginine. GO:0098820 trans-synaptic protein complex biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098820 A protein complex that spans the synaptic cleft and has parts in both the pre- and post-synaptic membranes. GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035242 EC:2.1.1.319|RESID:AA0069|RHEA:48096|RESID:AA0068 type I protein arginine methyltransferase activity|type I PRMT activity|S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-Nomega,Nomega-dimethyl-L-arginine-forming) Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the same terminal nitrogen (omega nitrogen) residue that was previously methylated, resulting in asymmetrical peptidyl-N(omega),N(omega)-dimethylated arginine residues. GO:0098821 BMP receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098821 Combining with a member of the bone morphogenetic protein (BMP) family, and transmitting a signal across the plasma membrane to initiate a change in cell activity. GO:0098830 presynaptic endosome biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098830 An endosome present in the presynapse that fuses with endocytic vesicles arising in the presynaptic endocytic zone. This organelle is believed to be involved in regeneration of synaptic vesicles. GO:1902689 negative regulation of NAD metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902689 negative regulation of NAD phosphorylation and dephosphorylation|down regulation of nicotinamide adenine dinucleotide metabolism|down-regulation of NAD phosphorylation and dephosphorylation|inhibition of nicotinamide adenine dinucleotide metabolism|down regulation of NAD metabolic process|downregulation of nicotinamide adenine dinucleotide metabolic process|negative regulation of oxidized nicotinamide adenine dinucleotide metabolism|down-regulation of oxidized nicotinamide adenine dinucleotide metabolism|downregulation of oxidized nicotinamide adenine dinucleotide metabolic process|inhibition of oxidized NAD metabolism|downregulation of NAD metabolic process|downregulation of oxidized NAD metabolic process|down-regulation of NAD (oxidized) metabolic process|negative regulation of NAD (oxidized) metabolic process|down regulation of oxidized nicotinamide adenine dinucleotide metabolic process|inhibition of oxidized nicotinamide adenine dinucleotide metabolic process|down regulation of NAD (oxidized) metabolism|inhibition of oxidized nicotinamide adenine dinucleotide metabolism|down-regulation of nicotinamide adenine dinucleotide metabolic process|negative regulation of nicotinamide adenine dinucleotide metabolic process|down regulation of oxidized NAD metabolic process|inhibition of NAD phosphorylation and dephosphorylation|downregulation of NAD (oxidized) metabolism|inhibition of oxidized NAD metabolic process|down-regulation of NAD metabolic process|down-regulation of NAD metabolism|negative regulation of NAD metabolism|downregulation of NAD (oxidized) metabolic process|inhibition of nicotinamide adenine dinucleotide metabolic process|down regulation of oxidized NAD metabolism|down-regulation of nicotinamide adenine dinucleotide metabolism|down regulation of NAD phosphorylation and dephosphorylation|negative regulation of nicotinamide adenine dinucleotide metabolism|down regulation of NAD (oxidized) metabolic process|inhibition of NAD metabolic process|down regulation of oxidized nicotinamide adenine dinucleotide metabolism|down-regulation of NAD (oxidized) metabolism|inhibition of NAD (oxidized) metabolic process|negative regulation of NAD (oxidized) metabolism|downregulation of oxidized NAD metabolism|downregulation of NAD phosphorylation and dephosphorylation|downregulation of NAD metabolism|downregulation of oxidized nicotinamide adenine dinucleotide metabolism|down-regulation of oxidized nicotinamide adenine dinucleotide metabolic process|negative regulation of oxidized nicotinamide adenine dinucleotide metabolic process|down regulation of NAD metabolism|downregulation of nicotinamide adenine dinucleotide metabolism|inhibition of NAD (oxidized) metabolism|inhibition of NAD metabolism|down regulation of nicotinamide adenine dinucleotide metabolic process|negative regulation of oxidized NAD metabolic process|down-regulation of oxidized NAD metabolism|negative regulation of oxidized NAD metabolism|down-regulation of oxidized NAD metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of NAD metabolic process. GO:2001226 negative regulation of chloride transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001226 Any process that stops, prevents or reduces the frequency, rate or extent of chloride transport. GO:2001227 quercitrin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_2001227 Interacting selectively and non-covalently with quercitrin. GO:1902687 glucosidase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902687 A protein complex which is capable of glucosidase activity. GO:2001228 regulation of response to gamma radiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001228 regulation of response to gamma ray|regulation of response to gamma-ray photon Any process that modulates the frequency, rate or extent of response to gamma radiation. GO:1902688 regulation of NAD metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902688 regulation of oxidized nicotinamide adenine dinucleotide metabolic process|regulation of oxidized NAD metabolic process|regulation of NAD (oxidized) metabolism|regulation of NAD (oxidized) metabolic process|regulation of oxidized NAD metabolism|regulation of NAD phosphorylation and dephosphorylation|regulation of oxidized nicotinamide adenine dinucleotide metabolism|regulation of NAD metabolism|regulation of nicotinamide adenine dinucleotide metabolism|regulation of nicotinamide adenine dinucleotide metabolic process Any process that modulates the frequency, rate or extent of NAD metabolic process. GO:2001229 negative regulation of response to gamma radiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001229 negative regulation of response to gamma-ray photon|negative regulation of response to gamma ray Any process that stops, prevents or reduces the frequency, rate or extent of response to gamma radiation. GO:1902685 positive regulation of receptor localization to synapse biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902685 up regulation of receptor localization to synapse|positive regulation of receptor localisation to synapse|up regulation of receptor localisation to synapse|upregulation of receptor localization to synapse|upregulation of receptor localisation to synapse|activation of receptor localization to synapse|up-regulation of receptor localization to synapse|up-regulation of receptor localisation to synapse|activation of receptor localisation to synapse Any process that activates or increases the frequency, rate or extent of receptor localization to synapse. GO:1902686 mitochondrial outer membrane permeabilization involved in programmed cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902686 mitochondrial membrane permeability transition involved in nonapoptotic programmed cell death|positive regulation of mitochondrial membrane permeability involved in caspase-independent apoptosis|positive regulation of mitochondrial membrane permeability involved in regulated cell death|MPT involved in programmed cell death|positive regulation of mitochondrial membrane permeability involved in PCD|MPT involved in caspase-independent apoptosis|mitochondrial outer membrane permeabilization during programmed cell death|mitochondrial permeability transition involved in nonapoptotic programmed cell death|positive regulation of transport across mitochondrial membrane involved in caspase-independent cell death|mitochondrial permeability transition involved in non-apoptotic programmed cell death|mitochondrial permeability transition involved in PCD|positive regulation of transport across mitochondrial membrane involved in regulated cell death|mitochondrial permeability transition involved in programmed cell death|mitochondrial membrane permeability transition involved in PCD|mitochondrial membrane permeability transition involved in non-apoptotic programmed cell death|mitochondrial permeability transition involved in caspase-independent apoptosis|MPT involved in nonapoptotic programmed cell death|mitochondrial membrane permeability transition involved in programmed cell death|positive regulation of mitochondrial membrane permeability involved in nonapoptotic programmed cell death|mitochondrial membrane permeability transition involved in caspase-independent apoptosis|mitochondrial membrane permeabilization involved in PCD|mitochondrial membrane permeabilization involved in non-apoptotic programmed cell death|mitochondrial membrane permeabilization involved in caspase-independent cell death|mitochondrial membrane permeabilization involved in programmed cell death|mitochondrial membrane permeabilization involved in regulated cell death|mitochondrial membrane permeabilization involved in caspase-independent apoptosis|positive regulation of transport across mitochondrial membrane involved in nonapoptotic programmed cell death|mitochondrial membrane permeability transition involved in caspase-independent cell death|mitochondrial membrane permeability transition involved in regulated cell death|positive regulation of mitochondrial membrane permeability involved in programmed cell death|mitochondrial permeability transition involved in caspase-independent cell death|mitochondrion outer membrane permeabilization involved in programmed cell death|positive regulation of transport across mitochondrial membrane involved in non-apoptotic programmed cell death|mitochondrial permeability transition involved in regulated cell death|mitochondrial membrane permeabilization involved in nonapoptotic programmed cell death|positive regulation of transport across mitochondrial membrane involved in caspase-independent apoptosis|positive regulation of mitochondrial membrane permeability involved in non-apoptotic programmed cell death|MPT involved in caspase-independent cell death|positive regulation of transport across mitochondrial membrane involved in PCD|MPT involved in regulated cell death|positive regulation of mitochondrial membrane permeability involved in caspase-independent cell death|MPT involved in non-apoptotic programmed cell death|MPT involved in PCD|positive regulation of transport across mitochondrial membrane involved in programmed cell death The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of a programmed cell death process. GO:0060240 negative regulation of signal transduction involved in conjugation with cellular fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060240 Any process that decreases the rate, frequency or extent of the series of molecular signals that bring about the relay, amplification or dampening of a signal generated in response to a cue, such as starvation or pheromone exposure, in organisms that undergo conjugation with cellular fusion. GO:1902683 regulation of receptor localization to synapse biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902683 regulation of receptor localisation to synapse Any process that modulates the frequency, rate or extent of receptor localization to synapse. GO:0060241 lysozyme inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0060241 Stops, prevents or reduces the activity of a lysozyme, an enzyme that hydrolyses the beta- (1,4) glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan. GO:0060242 contact inhibition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060242 Wikipedia:Contact_inhibition detection of cell density by contact stimulus involved in contact inhibition|detection of cell density by contact stimulus The series of events in which information about the density of cells in a population is received by direct cell-cell contact and is converted into a molecular signal, resulting in the cessation of cell growth or proliferation. GO:1902684 negative regulation of receptor localization to synapse biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902684 down-regulation of receptor localisation to synapse|negative regulation of receptor localisation to synapse|downregulation of receptor localization to synapse|down regulation of receptor localization to synapse|inhibition of receptor localization to synapse|downregulation of receptor localisation to synapse|down regulation of receptor localisation to synapse|inhibition of receptor localisation to synapse|down-regulation of receptor localization to synapse Any process that stops, prevents or reduces the frequency, rate or extent of receptor localization to synapse. GO:0060243 negative regulation of cell growth involved in contact inhibition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060243 The negative regulation of cell growth in response to increased cell density. GO:0035232 germ cell attraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035232 The directed movement of a germ cell from their site of production to the gonad, through the attraction of cells towards their target. GO:1902692 regulation of neuroblast proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902692 Any process that modulates the frequency, rate or extent of neuroblast proliferation. GO:0060244 negative regulation of cell proliferation involved in contact inhibition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060244 Any process that stops, prevents or reduces the rate or extent of cell proliferation in response to cell density. GO:1902693 superoxide dismutase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902693 A protein complex which is capable of superoxide dismutase activity. GO:0035233 germ cell repulsion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035233 The directed movement of a germ cell from their site of production to the gonad, through the repulsion of cells away from a tissue. GO:1902690 positive regulation of NAD metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902690 up-regulation of NAD metabolic process|positive regulation of nicotinamide adenine dinucleotide metabolism|up-regulation of oxidized NAD metabolic process|activation of oxidized NAD metabolic process|upregulation of NAD (oxidized) metabolic process|up regulation of oxidized NAD metabolism|up regulation of nicotinamide adenine dinucleotide metabolism|activation of oxidized NAD metabolism|up regulation of NAD phosphorylation and dephosphorylation|upregulation of nicotinamide adenine dinucleotide metabolic process|positive regulation of oxidized NAD metabolism|positive regulation of NAD phosphorylation and dephosphorylation|up-regulation of NAD (oxidized) metabolism|up regulation of oxidized nicotinamide adenine dinucleotide metabolism|activation of oxidized nicotinamide adenine dinucleotide metabolism|upregulation of NAD metabolism|upregulation of NAD metabolic process|positive regulation of oxidized nicotinamide adenine dinucleotide metabolism|positive regulation of oxidized nicotinamide adenine dinucleotide metabolic process|up-regulation of NAD (oxidized) metabolic process|up regulation of oxidized nicotinamide adenine dinucleotide metabolic process|activation of NAD phosphorylation and dephosphorylation|activation of NAD (oxidized) metabolic process|positive regulation of oxidized NAD metabolic process|upregulation of nicotinamide adenine dinucleotide metabolism|up regulation of nicotinamide adenine dinucleotide metabolic process|up regulation of oxidized NAD metabolic process|activation of nicotinamide adenine dinucleotide metabolic process|up-regulation of oxidized NAD metabolism|upregulation of NAD (oxidized) metabolism|positive regulation of nicotinamide adenine dinucleotide metabolic process|up-regulation of NAD phosphorylation and dephosphorylation|activation of NAD metabolism|up-regulation of NAD metabolism|up regulation of NAD metabolic process|up-regulation of oxidized nicotinamide adenine dinucleotide metabolism|activation of NAD metabolic process|upregulation of oxidized nicotinamide adenine dinucleotide metabolic process|positive regulation of NAD (oxidized) metabolic process|up-regulation of nicotinamide adenine dinucleotide metabolism|activation of nicotinamide adenine dinucleotide metabolism|up regulation of NAD (oxidized) metabolic process|upregulation of oxidized NAD metabolism|upregulation of oxidized NAD metabolic process|upregulation of NAD phosphorylation and dephosphorylation|up regulation of NAD (oxidized) metabolism|activation of NAD (oxidized) metabolism|up-regulation of nicotinamide adenine dinucleotide metabolic process|positive regulation of NAD (oxidized) metabolism|upregulation of oxidized nicotinamide adenine dinucleotide metabolism|positive regulation of NAD metabolism|activation of oxidized nicotinamide adenine dinucleotide metabolic process|up-regulation of oxidized nicotinamide adenine dinucleotide metabolic process|up regulation of NAD metabolism Any process that activates or increases the frequency, rate or extent of NAD metabolic process. GO:0060245 detection of cell density biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060245 The series of events in which information about the density of cells in a population is received and converted into a molecular signal. GO:0035234 ectopic germ cell programmed cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035234 programmed cell death, ectopic germ cells|programmed cell death of ectopic germ cells Programmed cell death of an errant germ line cell that is outside the normal migratory path or ectopic to the gonad. This is an important mechanism of regulating germ cell survival within the embryo. GO:2001220 obsolete negative regulation of G2 phase of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001220 negative regulation of G2 phase of mitotic cell cycle OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of G2 phase of mitotic cell cycle. GO:0060246 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0060246 GO:0035235 ionotropic glutamate receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035235 ionotropic glutamate receptor signalling pathway A series of molecular signals initiated by glutamate binding to a glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription. GO:1902691 respiratory basal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902691 airway basal cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a respiratory basal cell. GO:2001221 obsolete positive regulation of G2 phase of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001221 positive regulation of G2 phase of mitotic cell cycle OBSOLETE. Any process that activates or increases the frequency, rate or extent of G2 phase of mitotic cell cycle. GO:2001222 regulation of neuron migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001222 regulation of neuronal migration|regulation of neuron chemotaxis|regulation of neuron guidance Any process that modulates the frequency, rate or extent of neuron migration. GO:0060247 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0060247 GO:0035236 proctolin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035236 Combining with the neuropeptide proctolin, to initiate a change in cell activity. GO:2001223 negative regulation of neuron migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001223 negative regulation of neuron chemotaxis|negative regulation of neuron guidance|negative regulation of neuronal migration Any process that stops, prevents or reduces the frequency, rate or extent of neuron migration. GO:0060248 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0060248 GO:0035237 corazonin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035237 Combining with the neuropeptide corazonin to initiate a change in cell activity. GO:2001224 positive regulation of neuron migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001224 positive regulation of neuron guidance|positive regulation of neuronal migration|positive regulation of neuron chemotaxis Any process that activates or increases the frequency, rate or extent of neuron migration. GO:0060249 anatomical structure homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060249 anatomical structure maintenance A homeostatic process involved in the maintenance of an internal steady state within a defined anatomical structure of an organism, including control of cellular proliferation and death and control of metabolic function. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. GO:0098839 postsynaptic density membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098839 The membrane component of the postsynaptic density. This is the region of the postsynaptic membrane in which the population of neurotransmitter receptors involved in synaptic transmission are concentrated. GO:0035238 vitamin A biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035238 vitamin A biosynthesis|vitamin A anabolism|vitamin A synthesis|vitamin A formation The chemical reactions and pathways resulting in the formation of any of the vitamin A compounds, retinol, retinal (retinaldehyde) and retinoic acid. Animals cannot synthesize vitamin A de novo, but form it through oxidative cleavage of carotenoids. GO:2001225 regulation of chloride transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001225 Any process that modulates the frequency, rate or extent of chloride transport. GO:0035239 tube morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035239 The process in which the anatomical structures of a tube are generated and organized. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system. GO:0098837 postsynaptic recycling endosome biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098837 postsynaptic endosomal recycling compartment|postsynaptic recycling outpost A recycling endosome of the postsynapse. In postsynaptic terminals with dendritic spines, it is typically located at the base of a dendritic spine. It is involved in recycling of neurotransmitter receptors to the postsynaptic membrane. In some cases at least, this recycling is activated by postsynaptic signalling and so can play a role in long term potentiation. GO:0098838 folate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098838 folic acid transmembrane transport|reduced folate transmembrane transport The process in which a folic acid, or one of its derivatives (dihydrofolate, tetrahydrofolate, methylene-tetrahydrofolate or methyl-tetrahydrofolate) is transported across a membrane. GO:0098835 presynaptic endocytic zone membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098835 The region of the presynaptic membrane that is part of the presynaptic endocytic zone - where synaptic vesicles are endocytosed and recycled following release. GO:0098836 cytoskeleton of dendritic spine biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098836 The portion of the cytoskeleton that lies within a dendritic spine. The actin component of this cytoskeleton is involved in spine head remodelling in response to postsynaptic signalling. GO:0098833 presynaptic endocytic zone biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098833 A specialized region of the plasma membrane and underlying cytoplasm which surround the the active zone, into which synaptic vesicle membranes are recycled following exocytosis. It is especially enriched in endocytic proteins following intense activity. GO:0098834 presynaptic endocytic zone cytoplasmic component biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098834 cortex of presynaptic endocytic zone The cytoplasmic component of the presynaptic endocytic zone. GO:0098831 presynaptic active zone cytoplasmic component biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098831 presynaptic zone cortex|cortex of presynaptic active zone A specialized region below the presynaptic membrane, characterized by electron-dense material, a specialized cytoskeletal matrix and accumulated (associated) synaptic vesicles. GO:0035230 cytoneme biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0035230 Wikipedia:Membrane_nanotube membrane nanotube A long, thin, polarized cell projection that contains actin and can extend for distances many times the diameter of the cell. Cytonemes represent extensions of cell cytoplasm and typically have a diameter of approximately 0.2um. GO:0035231 cytoneme assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035231 cytoneme biogenesis Formation of a cytoneme, a long, thin and polarized actin-based cytoplasmic extension that projects from a cell. GO:0098832 peri-centrosomal recycling endosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098832 A recycling endosome that is organized around the microtubule organizing center, close to the nucleus. This is the main recycling endosome of most cells. It receives input from the Golgi as well as recycled molecules from early endosomes. GO:0098884 postsynaptic neurotransmitter receptor internalization biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098884 postsynaptic neurotransmitter receptor endocytosis A receptor-mediated endocytosis process that results in the internalization of a neurotransmitter receptor from the postsynaptic membrane endocytic zone into an endocytic vesicle. GO:0098885 modification of postsynaptic actin cytoskeleton biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098885 postsynaptic actin cytoskeleton remodelling Any process that modifies the structure of a postsynaptic actin cytoskeleton. GO:0098882 structural constituent of presynaptic active zone biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098882 structural constituent of active zone The action of a molecule that contributes to the structural integrity of a presynaptic active zone. GO:0098883 synapse pruning biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098883 synapse clearance|synapse removal|synapse elimination|synapse disassembly A cellular process that results in the controlled breakdown of synapse. After it starts the process is continuous until the synapse has disappeared. GO:0098880 maintenance of postsynaptic specialization structure biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098880 A process which maintains the organization and the arrangement of proteins in the presynaptic specialization. GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098881 neurotransmitter receptor insertion The exocytic fusion of neurotransmitter receptor-containing vesicles with plasma membrane, resulting in the integration of neurotransmitter receptors into the plasma membrane. This process includes tethering and docking steps that prepare vesicles for fusion. GO:0035229 positive regulation of glutamate-cysteine ligase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035229 upregulation of glutamate-cysteine ligase activity|stimulation of glutamate-cysteine ligase activity|up-regulation of glutamate-cysteine ligase activity|activation of glutamate-cysteine ligase activity|up regulation of glutamate-cysteine ligase activity Any process that activates or increases the activity of glutamate-cysteine ligase, typically by lowering its sensitivity to inhibition by glutathione and by increasing its affinity for glutamate. GO:1902698 pentose catabolic process to butyrate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902698 acidogenesis|pentose degradation to butyrate|pentose catabolism to butyrate|pentose breakdown to butyrate The chemical reactions and pathways resulting in the breakdown of pentose to butyrate. GO:0060270 main body follicle cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060270 The ovarian follicle cell migration process in which follicle cells migrate posteriorly to form a columnar epithelium over the oocyte. GO:1902699 pentose catabolic process to acetate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902699 pentose catabolism to acetate|pentose degradation to acetate|acidogenesis|pentose breakdown to acetate The chemical reactions and pathways resulting in the breakdown of pentose to acetate. GO:0060271 cilium assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060271 Reactome:R-HSA-5617833.2 cilium morphogenesis|cilium formation|cilium assembly|cilium organization|microtubule-based flagellum assembly|cilium biogenesis|ciliogenesis The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole. GO:1902696 glycine catabolic process to isobutanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902696 glycine catabolism to isobutanol|glycine degradation to isobutanol|glycine breakdown to isobutanol The chemical reactions and pathways resulting in the breakdown of glycine to isobutanol. GO:0060272 embryonic skeletal joint morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060272 The process in which the anatomical structures of skeletal joints are generated and organized during the embryonic phase. A skeletal joint is the connecting structure between the bones of the skeleton. GO:1902697 valine catabolic process to isobutanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902697 valine degradation to isobutanol|valine breakdown to isobutanol|valine catabolism to isobutanol The chemical reactions and pathways resulting in the breakdown of valine to isobutanol. GO:0060273 crying behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060273 The behavior in which an organism sheds tears, often accompanied by non-verbal vocalizations and in response to external or internal stimuli. GO:0060274 maintenance of stationary phase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060274 The homeostatic process in which a population of cells changes its metabolic activity resulting in the rate of death in the population equaling the rate of reproduction. Stationary phase can be in response to limited nutrients or a build-up of toxic substances in the environment. GO:1902694 superoxide dismutase copper chaperone complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902694 A protein complex which is capable of superoxide dismutase copper chaperone activity. GO:0060275 maintenance of stationary phase in response to starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060275 The homeostatic process in which a population of cells changes its metabolic activity resulting in the rate of death in the population equaling the rate of reproduction in response to limited nutrients in the environment. GO:1902695 metallochaperone complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902695 A protein complex which is capable of metallochaperone activity. GO:0035221 genital disc pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035221 The process that gives rise to the patterns of cell differentiation that will arise in the genital imaginal disc. GO:0060276 maintenance of stationary phase in response to toxin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060276 The homeostatic process in which a population of cells changes its metabolic activity resulting in the rate of death in the population equaling the rate of reproduction in response to a build-up of toxins in the environment. GO:0060277 obsolete negative regulation of transcription involved in G1 phase of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060277 negative regulation of transcription involved in G1 phase of mitotic cell cycle|negative regulation of transcription from RNA polymerase II promoter during G1 phase of mitotic cell cycle OBSOLETE. Any process that stop, prevents or decreases transcription as part of the G1 phase of the mitotic cell cycle. GO:0035222 wing disc pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035222 The process giving rise to the pattern of cell differentiation in the wing imaginal disc. GO:0035223 leg disc pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035223 The process that gives rise to the patterns of cell differentiation in the leg imaginal disc. GO:0060278 regulation of ovulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060278 Any process that modulates the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary. GO:0035224 genital disc anterior/posterior pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035224 The establishment, maintenance and elaboration of the anterior/posterior axis of the genital disc. An anterior and posterior compartment form in each of the three genital disc primoridia (the female genital disc primordium, the male genital disc primordium and the anal primordium). GO:0060279 positive regulation of ovulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060279 Any process that activates or increases the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary. GO:0035225 determination of genital disc primordium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035225 Allocation of embryonic cells to the genital imaginal disc founder populations. Early in development at the blastoderm stage, the anlage of the genital disc of both sexes consists of three primordia: the female genital primoridum lcoated anteriorly, the anal primoridum located posteriorly, and the male gential primordium between the two. GO:0035226 glutamate-cysteine ligase catalytic subunit binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035226 Interacting selectively and non-covalently with the catalytic subunit of glutamate-cysteine ligase. GO:0035227 regulation of glutamate-cysteine ligase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035227 Any process that modulates the activity of glutamate-cysteine ligase. GO:0035228 negative regulation of glutamate-cysteine ligase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035228 inhibition of glutamate-cysteine ligase activity|down-regulation of glutamate-cysteine ligase activity|downregulation of glutamate-cysteine ligase activity|down regulation of glutamate-cysteine ligase activity Any process that stops or reduces the activity of the enzyme glutamate-cysteine ligase. GO:0098888 extrinsic component of presynaptic membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098888 extrinsic component of presynaptic plasma membrane The component of the presynaptic membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:0098889 intrinsic component of presynaptic membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098889 intrinsic to presynaptic membrane The component of the presynaptic membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0098886 modification of dendritic spine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098886 Any process that modifies the structure of a dendritic spine. GO:0035220 wing disc development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035220 Progression of the wing disc over time, from its initial formation through to its metamorphosis to form adult structures including the wing hinge, wing blade and pleura. GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098887 postsynaptic neurotransmitter receptor endosomal trafficking The directed movement of neurotransmitter receptor from the postsynaptic endosome to the postsynaptic membrane in transport vesicles. GO:0098895 postsynaptic endosome membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098895 The lipid bilayer surrounding a postsynaptic endosome. GO:0098896 postsynaptic early endosome membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098896 The lipid bilayer surrounding a postsynaptic early endosome. GO:0098893 extrinsic component of postsynaptic endocytic zone biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098893 The component of the postsynaptic endocytic zone membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:0098894 extrinsic component of presynaptic endocytic zone membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098894 The component of the presynaptic endocytic zone membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:0098891 extrinsic component of presynaptic active zone membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098891 The component of the presynaptic active zone membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:0098892 extrinsic component of postsynaptic specialization membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098892 The component of the postsynaptic specialization membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:0098890 extrinsic component of postsynaptic membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098890 The component of the postsynaptic membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:0035218 leg disc development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035218 Progression of the leg imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the leg, coxa and ventral thoracic pleura. GO:0035219 prothoracic disc development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035219 Progression of the prothoracic disc over time, from its initial formation through to its metamorphosis to form the adult humerous and anterior spiracle. GO:0060260 regulation of transcription initiation from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060260 Any process that modulates the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter. GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060261 Any process that increases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter. GO:0060262 negative regulation of N-terminal protein palmitoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060262 Any process that decreases the rate frequency or extent of the covalent attachment of a palmitoyl group to the N-terminal amino acid residue of a protein. GO:0060263 regulation of respiratory burst biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060263 Any process that modulates the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. GO:0060264 regulation of respiratory burst involved in inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060264 regulation of respiratory burst involved in acute inflammatory response Any process that modulates the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. GO:0060265 positive regulation of respiratory burst involved in inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060265 positive regulation of respiratory burst involved in acute inflammatory response Any process that increases the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. GO:0035210 prepupal development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035210 The process whose specific outcome is the progression of the prepupa over time, from its formation to the mature structure. The prepupal stage is a life stage interposed between the larval and the pupal stages in insects that undergo a complete metamorphosis. The start of the pre-pupal stage is marked by pupariation, and the end is marked by pupation. GO:0035211 spermathecum morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035211 The process in which the anatomical structures of a spermathecum, a sperm storage organ, are generated and organized. Paired spermathecae lie at the anterior end of the insect uterus on the dorsal side. Each spermatheca consists of an oval shaped capsule, connected to the uterus by a spermathecal stalk. GO:0060266 negative regulation of respiratory burst involved in inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060266 negative regulation of respiratory burst involved in acute inflammatory response Any process that decreases the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. GO:0060267 positive regulation of respiratory burst biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060267 Any process that increases the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. GO:0035212 cell competition in a multicellular organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035212 Competitive interactions within multicellular organisms between cell populations that differ in growth rates, leading to the elimination of the slowest-growing cells. GO:0060268 negative regulation of respiratory burst biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060268 Any process that decreases the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. GO:0035213 clypeo-labral disc development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035213 development of structures derived from the clypeo-labral disc The process whose specific outcome is the progression of the clypeo-labral disc over time, from its formation to the metamorphosis to form adult structures. The clypeo-labral disc develops into the labrum, anterior cibarial plate, fish trap bristles, epistomal sclerite. GO:0060269 centripetally migrating follicle cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060269 The cell migration process in which a follicle cell migrates as part of an epithelial sheet between the nurse cells and the oocyte. At the end of migration, they cover the anterior of the oocyte. GO:0035214 eye-antennal disc development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035214 Progression of the eye-antennal imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the eye, antenna, head capsule and maxillary palps. GO:0035215 genital disc development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035215 Progression of the genital imaginal disc over time, from its initial formation through to its metamorphosis to form the adult terminalia, comprising the entire set of internal and external genitalia and analia. Both sexes of Drosophila have a single genital disc formed from the female and male genital primordia, and the anal primordium. The anal primordium develops in both sexes, forming either male or female analia. However, only one of the genital primordia develops in each sex, forming either the male or the female genitalia. GO:0035216 haltere disc development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035216 Progression of the haltere imaginal disc over time, from its initial formation through to its metamorphosis to form the adult capitellum, pedicel, haltere sclerite, metathoracic spiracle and metanotum. GO:0035217 labial disc development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035217 Progression of the labial imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including parts of the proboscis. GO:0098899 spine apparatus lumen biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098899 The volume enclosed by the spine apparatus membrane. GO:0098897 spine apparatus membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098897 The lipid bilayer surrounding the spine apparatus. GO:0098898 dense core granule lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098898 dense core vesicle lumen The volume enclosed by the dense core granule membrane. GO:0098862 cluster of actin-based cell projections biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098862 A cell part consisting of multiple, closely packed actin-based cell projections. GO:0098863 nuclear migration by microtubule mediated pushing forces biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098863 The directed movement of the nucleus by pushing forces exerted by polymerization of backward-extending microtubules. GO:0098860 actin filament bundle of stereocilium biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098860 A bundle of hundreds of cross-linked actin filaments (an actin cable), that is the supporting structure of a stereocilium. Filaments are oriented such that the the plus (barbed) ends are at the tip of the protrusion and are capped by a tip complex which bridges to the plasma membrane. GO:0098861 actin filament bundle of filopodium biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098861 A parallel bundle of actin filaments that is part of filopodium. Filaments are oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex. GO:0035207 negative regulation of hemocyte proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035207 down-regulation of hemocyte proliferation|negative regulation of arthropod blood cell proliferation|downregulation of hemocyte proliferation|down regulation of hemocyte proliferation|inhibition of hemocyte proliferation Any process that stops, prevents or reduces the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster. GO:0060290 transdifferentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060290 Wikipedia:Transdifferentiation The conversion of a differentiated cell of one fate into a differentiated cell of another fate without first undergoing cell division or reversion to a more primitive or stem cell-like fate. GO:0035208 positive regulation of hemocyte proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035208 positive regulation of arthropod blood cell proliferation|up regulation of hemocyte proliferation|upregulation of hemocyte proliferation|stimulation of hemocyte proliferation|activation of hemocyte proliferation|up-regulation of hemocyte proliferation Any process that activates or increases the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) that are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster. GO:0060291 long-term synaptic potentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060291 long-term potentiation|LTP A process that modulates synaptic plasticity such that synapses are changed resulting in the increase in the rate, or frequency of synaptic transmission at the synapse. GO:0060292 long-term synaptic depression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060292 LTD|long term depression|long term synaptic depression A process that modulates synaptic plasticity such that synapses are changed resulting in the decrease in the rate, or frequency of synaptic transmission at the synapse. GO:0035209 pupal development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035209 The process whose specific outcome is the progression of the pupa over time, from its formation to the mature structure. The pupa is a dormant life stage interposed between the larval and the adult stages in insects that undergo a complete metamorphosis. GO:0060293 germ plasm biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0060293 Wikipedia:Germ_plasm Differentiated cytoplasm associated with a pole of an oocyte, egg or early embryo that will be inherited by the cells that will give rise to the germ line. GO:0060294 cilium movement involved in cell motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060294 Movement of cilia mediated by motor proteins that contributes to the movement of a cell. GO:0060295 regulation of cilium movement involved in cell motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060295 Any process that modulates the rate frequency or extent of cilium movement involved in ciliary motility. GO:0060296 regulation of cilium beat frequency involved in ciliary motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060296 Any process that modulates the frequency of cilium beating involved in ciliary motility. GO:0060297 regulation of sarcomere organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060297 regulation of sarcomere organisation Any process that modulates the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs. GO:0060298 positive regulation of sarcomere organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060298 positive regulation of sarcomere organisation Any process that increases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs. GO:0060299 negative regulation of sarcomere organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060299 negative regulation of sarcomere organisation Any process that decreases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs. GO:0035200 leg disc anterior/posterior pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035200 The establishment, maintenance and elaboration of the anterior/posterior axis of the leg imaginal disc. GO:0035201 leg disc anterior/posterior lineage restriction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035201 Formation and/or maintenance of a lineage boundary between anterior and posterior compartments of the leg disc that cells cannot cross, thus separating the populations of cells in each compartment. GO:0035202 tracheal pit formation in open tracheal system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035202 tracheal sac formation|tracheal placode invagination Formation of the tracheal pits, the first tube-like structures to form in the open tracheal system. Once cells are determined to their tracheal cell fate, the tracheal pits arise by invagination of each ectodermal cluster of tracheal placode cells, between 5 and 7 hours after egg laying. An example of this is found in Drosophila melanogaster. GO:0035203 regulation of lamellocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035203 Any process that modulates the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes. GO:0035204 negative regulation of lamellocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035204 down-regulation of lamellocyte differentiation|inhibition of lamellocyte differentiation|down regulation of lamellocyte differentiation|downregulation of lamellocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes. GO:0035205 positive regulation of lamellocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035205 activation of lamellocyte differentiation|stimulation of lamellocyte differentiation|up-regulation of lamellocyte differentiation|upregulation of lamellocyte differentiation|up regulation of lamellocyte differentiation Any process that activates or increases the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes. GO:0035206 regulation of hemocyte proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035206 regulation of arthropod blood cell proliferation Any process that modulates the frequency, rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster. GO:0098868 bone growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098868 The increase in size or mass of a bone that contributes to the shaping of that bone. GO:0098869 cellular oxidant detoxification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098869 Any process carried out at the cellular level that reduces or removes the toxicity superoxide radicals or hydrogen peroxide. GO:0098866 multivesicular body fusion to apical plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098866 The fusion of the membrane of a multivesicular body with the apical plasma membrane, resulting in release of exosomes from the cell. GO:0098867 intramembranous bone growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098867 The increase in size or mass of an intramembranous bone that contributes to the shaping of the bone. GO:0098864 modification by symbiont of host tight cell-cell junction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098864 The process in which a symbiont organism effects a change in the structure or function of its host tight junction, a cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other. GO:0098865 modification by symbiont of host bicellular tight junctions biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098865 The process in which an organism effects a change in the structure or function of its host bicellular tight junctions, an occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet. GO:0098873 neuronal action potential back-propagation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098873 Propagation of an action potential in a neuron, from its site of initiation (typically the axon hillock) towards the soma. GO:0098874 spike train biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098874 spike-train|burst of action potentials A series of sequential, propagated action potentials occurring in a single cell. GO:0098871 postsynaptic actin cytoskeleton biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098871 The actin cytoskeleton that is part of a postsynapse. GO:0098872 G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098872 G-protein coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration|G-protein coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium levels A G protein-coupled neurotransmitter receptor activity occurring in the postsynaptic membrane, that is involved in regulating the cytosolic concentration of calcium ions in the postsynapse. GO:0098870 action potential propagation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098870 The propagation of an action potential along the plane of an excitable membrane. Action potentials typically propagate once triggered because the depolarization of adjacent membrane regions due to an action potential crosses the firing threshold. GO:0060280 negative regulation of ovulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060280 Any process that stops, prevents, or reduces the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary. GO:0060281 regulation of oocyte development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060281 Any process that modulates the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. GO:0060282 positive regulation of oocyte development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060282 Any process that increases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. GO:0060283 negative regulation of oocyte development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060283 Any process that decreases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. GO:0060284 regulation of cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060284 Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. GO:0060285 cilium-dependent cell motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060285 microtubule-based flagellar cell motility|ciliary cell motility|cilium cell motility Cell motility due to the motion of one or more eukaryotic cilia. A eukaryotic cilium is a specialized organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole. GO:0060286 obsolete flagellar cell motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060286 flagellar cell motility OBSOLETE. Cell motility due to the motion of one or more flagella. GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060287 cilium movement involved in determinationof L/R asymmetry|nodal cilium movement involved in determination of left/right asymmetry|Kuppfer's vesicle cilium movement involved in determination of left/right asymmetry The movement of cilia of epithelial cells of the Left Right Organizer (LRO), also referred to as the node in mouse or the Kupffer's vesicle in zebrafish, resulting in the leftward fluid flow across the LRO and generation or transport of a signal which determines asymmetry in an organism's body plan with respect to the left and right halves. GO:0060288 formation of a compartment boundary biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060288 compartment boundary formation Formation of a lineage restriction boundary within a developing tissue which does not correspond to some morphological barrier. GO:0060289 compartment boundary maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060289 A homeostatic process involved in the maintenance of a compartment boundary. A compartment boundary is a lineage restriction boundary within a developing tissue which does not correspond to some morphological barrier. GO:0098879 structural constituent of postsynaptic specialization biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098879 The action of a molecule that contributes to the structural integrity of a postsynaptic specialization. GO:0098877 neurotransmitter receptor transport to plasma membrane biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098877 The directed movement of neurotransmitter receptor to the plasma membrane in transport vesicles. GO:0098878 neurotransmitter receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098878 Any protein complex that is capable of functioning as a neurotransmitter receptor. GO:0098875 epididymosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098875 A microvesicle of the epididymal fluid, from which spermatozoa aquire membrane proteins. GO:0098876 vesicle-mediated transport to the plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098876 The directed movement of substances to the plasma membrane in transport vesicles that fuse with the plasma membrane by exocytosis. GO:0050822 peptide stabilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050822 peptide stabilisation|peptide stabilization activity Any process involved in maintaining the structure and integrity of a peptide and preventing it from being degraded. GO:0050823 peptide antigen stabilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050823 peptide antigen stabilization activity Any process involved in maintaining the structure and integrity of a peptide antigen and preventing it from being degraded. GO:0050820 positive regulation of coagulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050820 up-regulation of coagulation|upregulation of coagulation|positive regulation of clotting|up regulation of coagulation|activation of coagulation|stimulation of coagulation Any process that activates or increases the frequency, rate or extent of coagulation. GO:0050821 protein stabilization biolink:BiologicalProcess go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0050821 protein stabilization activity|protein sequestering|lysosomal protein stabilization|protein stabilisation|positive regulation of protein stability Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation. GO:0050826 response to freezing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050826 antifreeze activity|ice nucleation inhibitor activity Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a freezing stimulus, temperatures below 0 degrees Celsius. GO:0050827 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050827 GO:0050824 obsolete water binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050824 OBSOLETE. Interacting selectively and non-covalently with water (H2O). GO:0050825 ice binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050825 antifreeze activity|ice nucleation inhibitor activity|ice crystal binding|ice nucleation activity Interacting selectively and non-covalently with ice, water reduced to the solid state by cold temperature. It is a white or transparent colorless substance, crystalline, brittle, and viscoidal. GO:0050828 regulation of liquid surface tension biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050828 regulation of surface tension of a liquid|surfactant activity Any process that modulates the surface tension of a liquid. Surface tension is the property that makes a liquid behave as if it had an elastic skin on its surface at the interface with a gas or an immiscible liquid. GO:0050829 defense response to Gram-negative bacterium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050829 defense response to Gram-negative bacteria|defence response to Gram-negative bacteria|Gram-negative antibacterial peptide activity|defence response to Gram-negative bacterium Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism. GO:2001273 obsolete regulation of glucose import in response to insulin stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001273 regulation of cellular glucose import in response to insulin stimulus OBSOLETE. Any process that modulates the frequency, rate or extent of glucose import in response to insulin stimulus. GO:2001274 obsolete negative regulation of glucose import in response to insulin stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001274 negative regulation of cellular glucose import in response to insulin stimulus OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of glucose import in response to insulin stimulus. GO:2001275 obsolete positive regulation of glucose import in response to insulin stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001275 positive regulation of cellular glucose import in response to insulin stimulus OBSOLETE. Any process that activates or increases the frequency, rate or extent of glucose import in response to insulin stimulus. CHEBI:86338 3-hydroxydecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86338 GO:2001276 regulation of leucine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001276 regulation of leucine biosynthesis|regulation of leucine anabolism|regulation of leucine synthesis|regulation of leucine formation Any process that modulates the frequency, rate or extent of leucine biosynthetic process. CHEBI:86339 D-5-monosubstituted hydantoin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86339 GO:2001277 negative regulation of leucine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001277 negative regulation of leucine formation|negative regulation of leucine anabolism|negative regulation of leucine biosynthesis|negative regulation of leucine synthesis Any process that stops, prevents or reduces the frequency, rate or extent of leucine biosynthetic process. GO:2001278 positive regulation of leucine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001278 positive regulation of leucine anabolism|positive regulation of leucine synthesis|positive regulation of leucine formation|positive regulation of leucine biosynthesis Any process that activates or increases the frequency, rate or extent of leucine biosynthetic process. GO:2001279 regulation of unsaturated fatty acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001279 regulation of unsaturated fatty acid synthesis|regulation of unsaturated fatty acid formation|regulation of polyunsaturated fatty acid biosynthesis|regulation of fatty acid desaturation|regulation of unsaturated fatty acid biosynthesis|regulation of unsaturated fatty acid anabolism Any process that modulates the frequency, rate or extent of unsaturated fatty acid biosynthetic process. GO:2001270 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001270 regulation of effector caspase activity Any process that modulates the frequency, rate or extent of cysteine-type endopeptidase activity involved in execution phase of apoptosis. GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001271 negative regulation of effector caspase activity Any process that stops, prevents or reduces the frequency, rate or extent of cysteine-type endopeptidase activity involved in execution phase of apoptosis. GO:2001272 positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001272 positive regulation of effector caspase activity Any process that activates or increases the frequency, rate or extent of cysteine-type endopeptidase activity involved in execution phase of apoptosis. GO:0050830 defense response to Gram-positive bacterium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050830 defence response to Gram-positive bacterium|defence response to Gram-positive bacteria|Gram-positive antibacterial peptide activity|defense response to Gram-positive bacteria Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism. PO:0000112 shoot axis epidermis biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000112 シュート軸表皮 (Japanese, exact)|epidermis del eje del tallo (Spanish, exact)|branch epidermis (narrow) A portion of shoot system epidermis (PO:0006035) that is part of a shoot axis (PO:0025029). GO:0050833 pyruvate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050833 Reactome:R-HSA-372342 monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity Enables the transfer of pyruvate, 2-oxopropanoate, from one side of a membrane to the other. PO:0000115 socket cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000115 ソケット細胞 (Japanese, exact)|trichome support cell (related)|célula de encaje (Spanish, exact)|cell located at the base of the trichome (related) A shoot epidermal cell (PO:0025165) that surrounds a trichome (PO:0000282) and provides its support. GO:0050834 molybdenum incorporation via L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050834 RESID:AA0355 The incorporation of molybdenum into a protein by L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide. GO:0050831 male-specific defense response to bacterium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050831 male-specific defence response to bacteria|male-specific antibacterial peptide activity|male-specific defense response to bacteria|male-specific defence response to bacterium A set of reactions, specific to males, that are triggered in response to the presence of a bacterium that act to protect the cell or organism. GO:0050832 defense response to fungus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050832 defence response to fungus|defense response to fungi|response to parasitic fungus|response to parasitic fungi|resistance response to pathogenic fungi|defense response to fungus, incompatible interaction|defence response to fungi|resistance response to pathogenic fungus Reactions triggered in response to the presence of a fungus that act to protect the cell or organism. GO:0050837 peptide cross-linking via L-cysteinyl-L-selenocysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050837 RESID:AA0358 The formation of a selenide-sulfide bond to form the cystine-like L-cysteinyl-L-selenocysteine, as in vertebrate selenopeptide P. CHEBI:62372 UDP-2-acetamido-2,6-dideoxy-beta-L-talose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62372 GO:0050838 peptidyl-5-hydroxy-L-lysine trimethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050838 RESID:AA0359 The methylation of 5-hydroxy-L-lysine to form peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine. CHEBI:62370 alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62370 GO:0050835 iron incorporation into iron-sulfur cluster via tris-L-cysteinyl S-adenosylmethion-N,O-diyl tetrairon tetrasulfide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050835 RESID:AA0356 The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl S-adenosylmethion-N,O-diyl tetrairon tetrasulfide. CHEBI:86320 1alpha,25-dihydroxyvitamin D2 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86320 GO:0050836 iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-arginyl diiron disulfide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050836 RESID:AA0357 The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl L-arginyl diiron disulfide. CHEBI:86321 3-hydroxyoctanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86321 CHEBI:62377 UDP-2-acetamido-2,6-dideoxy-beta-L-lyxo-hex-4-ulose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62377 CHEBI:86322 alkaloid antibiotic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86322 GO:0050839 cell adhesion molecule binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050839 cell adhesion receptor activity|adhesive extracellular matrix constituent|cell adhesion molecule activity|CAM binding Interacting selectively and non-covalently with a cell adhesion molecule. CHEBI:86323 conazole antifungal agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86323 CHEBI:62375 UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-hex-4-ulose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62375 CHEBI:86324 quinolone antibiotic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86324 GO:2001284 regulation of BMP secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001284 regulation of BMP protein secretion|regulation of bone morphogenetic protein secretion Any process that modulates the frequency, rate or extent of BMP secretion. GO:2001285 negative regulation of BMP secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001285 negative regulation of bone morphogenetic protein secretion|negative regulation of BMP protein secretion Any process that stops, prevents or reduces the frequency, rate or extent of BMP secretion. GO:2001286 regulation of caveolin-mediated endocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001286 regulation of caveolae-mediated endocytosis|regulation of caveolin-dependent endocytosis|regulation of caveolae-dependent endocytosis Any process that modulates the frequency, rate or extent of caveolin-mediated endocytosis. CHEBI:86327 antifungal drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86327 GO:2001287 negative regulation of caveolin-mediated endocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001287 negative regulation of caveolin-dependent endocytosis|negative regulation of caveolae-dependent endocytosis|negative regulation of caveolae-mediated endocytosis Any process that stops, prevents or reduces the frequency, rate or extent of caveolin-mediated endocytosis. CHEBI:86328 antifungal agrochemical biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86328 GO:2001288 positive regulation of caveolin-mediated endocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001288 positive regulation of caveolin-dependent endocytosis|positive regulation of caveolae-dependent endocytosis|positive regulation of caveolae-mediated endocytosis Any process that activates or increases the frequency, rate or extent of caveolin-mediated endocytosis. GO:2001289 lipid X metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001289 2-deoxy-3-O-[(3R)-3-hydroxytetradecanoyl]-2-{[(3R)-3-hydroxytetradecanoyl]amino}-1-O-phosphono-alpha-D-glucopyranose metabolic process|2-deoxy-3-O-[(3R)-3-hydroxytetradecanoyl]-2-{[(3R)-3-hydroxytetradecanoyl]amino}-1-O-phosphono-alpha-D-glucopyranose metabolism|Lipid X metabolic process|2,3-Bis(beta-hydoroxymyristoyl)-beta-D-glucosaminyl 1-phosphate metabolic process|2,3-Bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate metabolism|Lipid X metabolism|lipid X metabolism|2,3-Bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate metabolic process|2,3-Bis(beta-hydoroxymyristoyl)-beta-D-glucosaminyl 1-phosphate metabolism The chemical reactions and pathways involving lipid X, 2,3-diacylglucosamine 1-phosphate. GO:2001280 positive regulation of unsaturated fatty acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001280 positive regulation of unsaturated fatty acid anabolism|positive regulation of fatty acid desaturation|positive regulation of unsaturated fatty acid synthesis|positive regulation of unsaturated fatty acid biosynthesis|positive regulation of unsaturated fatty acid formation|positive regulation of polyunsaturated fatty acid biosynthesis Any process that activates or increases the frequency, rate or extent of unsaturated fatty acid biosynthetic process. GO:2001281 regulation of muscle cell chemotaxis toward tendon cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001281 regulation of muscle cell chemotaxis towards tendon cell|regulation of muscle cell attraction Any process that modulates the frequency, rate or extent of muscle cell chemotaxis toward tendon cell. GO:2001282 negative regulation of muscle cell chemotaxis toward tendon cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001282 negative regulation of muscle cell attraction|arrest of muscle cell chemotaxis|negative regulation of muscle cell chemotaxis towards tendon cell Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of a muscle cell towards a tendon cell in response to an external stimulus. For example, when the muscle cell arrives at the target tendon cell, migration is arrested so that attachments can be made between the cells. GO:2001283 Roundabout signaling pathway involved in muscle cell chemotaxis toward tendon cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001283 Roundabout signalling pathway involved in muscle cell chemotaxis toward tendon cell|Roundabout signalling pathway involved in muscle cell chemotaxis towards tendon cell|Roundabout signaling pathway involved in muscle cell attraction|ROBO/SLIT signaling pathway involved in muscle cell chemotaxis towards tendon cell|ROBO signaling pathway involved in muscle cell chemotaxis towards tendon cell|Roundabout signalling pathway involved in muscle cell attraction|ROBO/SLIT signaling pathway involved in muscle cell attraction|ROBO signaling pathway involved in muscle cell attraction|ROBO signaling pathway involved in muscle cell chemotaxis toward tendon cell|ROBO/SLIT signaling pathway involved in muscle cell chemotaxis toward tendon cell|Roundabout signaling pathway involved in muscle cell chemotaxis towards tendon cell Any Roundabout signaling pathway that is involved in the directed movement of a muscle cell towards a tendon cell in response to an external stimulus. GO:0050840 extracellular matrix binding biolink:MolecularActivity go-plus goslim_pir|goslim_chembl http://purl.obolibrary.org/obo/GO_0050840 adhesive extracellular matrix constituent|extracellular matrix constituent binding Interacting selectively and non-covalently with a component of the extracellular matrix. GO:0050841 peptidyl-N6,N6,N6-trimethyl-lysine hydroxylation to peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050841 RESID:AA0359 peptidyl-trimethyl-lysine hydroxylase activity|peptidyl trimethyl lysine hydroxylase activity The hydroxylation of peptidyl-N6,N6,N6-trimethyl-L-lysine to form peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine. GO:0050844 peptidyl-selenocysteine modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050844 The modification of peptidyl-selenocysteine. GO:0050845 teichuronic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050845 teichuronic acid anabolism|teichuronic acid biosynthesis|teichuronic acid synthesis|teichuronic acid formation The chemical reactions and pathways resulting in the formation of teichuronic acid, a polymer containing chains of uronic acids and N-acetylglucosamine found in the cell wall, membrane or capsule of Gram-positive bacteria. GO:0050842 copper incorporation via L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050842 RESID:AA0355 The incorporation of copper into a protein by L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide. GO:0050843 S-adenosylmethionine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050843 S-adenosyl methionine catabolism|S-adenosylmethionine degradation|S-adenosyl methionine catabolic process|S-adenosylmethionine breakdown|SAM catabolic process|S-adenosylmethionine catabolism The chemical reactions and pathways resulting in the breakdown of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism. GO:0050848 regulation of calcium-mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050848 regulation of calcium-mediated signalling Any process that modulates the frequency, rate or extent of calcium-mediated signaling, the process in which a cell uses calcium ions to convert an extracellular signal into a response. CHEBI:62383 1D-myo-inositol 2-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62383 GO:0050849 negative regulation of calcium-mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050849 down-regulation of calcium-mediated signaling|downregulation of calcium-mediated signaling|down regulation of calcium-mediated signaling|inhibition of calcium-mediated signaling|negative regulation of calcium-mediated signalling Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-mediated signaling. GO:0050846 teichuronic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050846 teichuronic acid metabolism The chemical reactions and pathways involving teichuronic acid, a polymer containing chains of uronic acids and N-acetylglucosamine found in the cell wall, membrane or capsule of Gram-positive bacteria. GO:0050847 progesterone receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050847 progesterone receptor signalling pathway Any series of molecular signals generated as a consequence of a progesterone binding to its receptor. GO:2001295 malonyl-CoA biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001295 malonyl-CoA synthesis|malonyl-CoA formation|malonyl-CoA biosynthesis|malonyl-CoA anabolism The chemical reactions and pathways resulting in the formation of malonyl-CoA, the S-malonyl derivative of coenzyme A. GO:2001296 N(omega)-methyl-L-arginine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001296 N(omega)-methyl-L-arginine metabolism The chemical reactions and pathways involving N(omega)-methyl-L-arginine. CHEBI:86359 L-gluconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86359 GO:2001297 N(omega)-methyl-L-arginine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001297 N(omega)-methyl-L-arginine catabolism|N(omega)-methyl-L-arginine degradation|N(omega)-methyl-L-arginine breakdown The chemical reactions and pathways resulting in the breakdown of N(omega)-methyl-L-arginine. GO:2001298 N(omega),N(omega)-dimethyl-L-arginine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001298 N(omega),N(omega)-dimethyl-L-arginine metabolism The chemical reactions and pathways involving N(omega),N(omega)-dimethyl-L-arginine, a methyl-L-arginine having two methyl groups both attached to the primary amino moiety of the guanidino group. GO:2001299 N(omega),N(omega)-dimethyl-L-arginine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001299 N(omega),N(omega)-dimethyl-L-arginine catabolism|N(omega),N(omega)-dimethyl-L-arginine degradation|N(omega),N(omega)-dimethyl-L-arginine breakdown The chemical reactions and pathways resulting in the breakdown of N(omega),N(omega)-dimethyl-L-arginine, a methyl-L-arginine having two methyl groups both attached to the primary amino moiety of the guanidino group. GO:2001290 hydroperoxide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001290 hydroperoxide metabolism The chemical reactions and pathways involving a hydroperoxide. GO:2001291 codeine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001291 codeine metabolism The chemical reactions and pathways involving codeine, an alkaloid found in the opium poppy, Papaver somniferum var. album. Codeine has analgesic, anti-tussive and anti-diarrhoeal properties. GO:2001292 codeine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001292 codeine catabolism|codeine degradation|codeine breakdown The chemical reactions and pathways resulting in the breakdown of codeine, an alkaloid found in the opium poppy, Papaver somniferum var. album. Codeine has analgesic, anti-tussive and anti-diarrhoeal properties. GO:2001293 malonyl-CoA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001293 malonyl-CoA metabolism The chemical reactions and pathways involving malonyl-CoA, the S-malonyl derivative of coenzyme A. GO:2001294 malonyl-CoA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001294 malonyl-CoA catabolism|malonyl-CoA degradation|malonyl-CoA breakdown The chemical reactions and pathways resulting in the breakdown of malonyl-CoA, the S-malonyl derivative of coenzyme A. GO:1902609 (R)-2-hydroxy-alpha-linolenic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902609 (R)-2-hydroxy-alpha-linolenic acid synthesis|(R)-2-hydroxy-alpha-linolenic acid formation|(R)-2-hydroxy-alpha-linolenic acid biosynthesis|2-hydroxy-octadecatrienoic acid biosynthesis|(R)-2-hydroxy-alpha-linolenic acid anabolism The chemical reactions and pathways resulting in the formation of (R)-2-hydroxy-alpha-linolenic acid. GO:0050851 antigen receptor-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050851 antigen receptor-mediated signalling pathway A series of molecular signals initiated by the cross-linking of an antigen receptor on a B or T cell. GO:0050852 T cell receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050852 T lymphocyte receptor signalling pathway|T lymphocyte receptor signaling pathway|T-lymphocyte receptor signaling pathway|T-cell receptor signalling pathway|TCR signaling pathway|T-cell receptor signaling pathway|T-lymphocyte receptor signalling pathway A series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell. GO:1902607 negative regulation of large conductance calcium-activated potassium channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902607 downregulation of large conductance calcium-activated potassium channel activity|downregulation of large conductance KCa channels|down regulation of BK channel activity|down regulation of BK KCa channels|down regulation of BK calcium-activated potassium channel activity|down regulation of large conductance KCa channels|down regulation of large conductance calcium-activated potassium channel activity|downregulation of BK calcium-activated potassium channel activity|downregulation of BK KCa channels|downregulation of BK channel activity|inhibition of large conductance calcium-activated potassium channel activity|inhibition of large conductance KCa channels|negative regulation of BK calcium-activated potassium channel activity|down-regulation of BK KCa channels|negative regulation of BK channel activity|down-regulation of BK channel activity|negative regulation of BK KCa channels|down-regulation of BK calcium-activated potassium channel activity|inhibition of BK KCa channels|inhibition of BK calcium-activated potassium channel activity|down-regulation of large conductance KCa channels|down-regulation of large conductance calcium-activated potassium channel activity|negative regulation of large conductance KCa channels|inhibition of BK channel activity Any process that stops, prevents or reduces the frequency, rate or extent of large conductance calcium-activated potassium channel activity. GO:1902608 positive regulation of large conductance calcium-activated potassium channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902608 positive regulation of large conductance KCa channels|up regulation of large conductance calcium-activated potassium channel activity|up regulation of large conductance KCa channels|upregulation of BK channel activity|upregulation of BK calcium-activated potassium channel activity|upregulation of BK KCa channels|upregulation of large conductance KCa channels|upregulation of large conductance calcium-activated potassium channel activity|up regulation of BK calcium-activated potassium channel activity|up regulation of BK KCa channels|up regulation of BK channel activity|positive regulation of BK channel activity|activation of BK calcium-activated potassium channel activity|positive regulation of BK KCa channels|activation of BK KCa channels|positive regulation of BK calcium-activated potassium channel activity|activation of BK channel activity|up-regulation of large conductance calcium-activated potassium channel activity|up-regulation of large conductance KCa channels|activation of large conductance calcium-activated potassium channel activity|activation of large conductance KCa channels|up-regulation of BK calcium-activated potassium channel activity|up-regulation of BK channel activity|up-regulation of BK KCa channels Any process that activates or increases the frequency, rate or extent of large conductance calcium-activated potassium channel activity. GO:0050850 positive regulation of calcium-mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050850 upregulation of calcium-mediated signaling|positive regulation of calcium-mediated signalling|stimulation of calcium-mediated signaling|activation of calcium-mediated signaling|up-regulation of calcium-mediated signaling|up regulation of calcium-mediated signaling Any process that activates or increases the frequency, rate or extent of calcium-mediated signaling. GO:0050855 regulation of B cell receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050855 regulation of B lymphocyte receptor signalling pathway|regulation of B lymphocyte receptor signaling pathway|regulation of B-cell receptor signalling pathway|regulation of B-lymphocyte receptor signalling pathway|regulation of B-lymphocyte receptor signaling pathway|regulation of B-cell receptor signaling pathway|regulation of B cell receptor signalling pathway Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell. GO:1902605 heterotrimeric G-protein complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902605 heterotrimeric G-protein complex formation|heterotrimeric G-protein GTPase, beta-subunit assembly|heterotrimeric G-protein GTPase activity assembly|heterotrimeric G-protein GTPase, beta-subunit formation|heterotrimeric G-protein GTPase, alpha-subunit assembly|heterotrimeric G-protein GTPase, gamma-subunit formation|heterotrimeric G-protein GTPase, gamma-subunit assembly|heterotrimeric G-protein GTPase activity formation|heterotrimeric G-protein GTPase, alpha-subunit formation The aggregation, arrangement and bonding together of a set of components to form a heterotrimeric G-protein complex. GO:0050856 regulation of T cell receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050856 regulation of T-cell receptor signalling pathway|regulation of T-lymphocyte receptor signalling pathway|regulation of T-lymphocyte receptor signaling pathway|regulation of TCR signaling pathway|regulation of T-cell receptor signaling pathway|regulation of T lymphocyte receptor signalling pathway|regulation of T lymphocyte receptor signaling pathway Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell. GO:1902606 regulation of large conductance calcium-activated potassium channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902606 regulation of large conductance KCa channels|regulation of BK calcium-activated potassium channel activity|regulation of BK KCa channels|regulation of BK channel activity Any process that modulates the frequency, rate or extent of large conductance calcium-activated potassium channel activity. GO:0050853 B cell receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050853 B-cell receptor signalling pathway|B-lymphocyte receptor signaling pathway|B-lymphocyte receptor signalling pathway|B-cell receptor signaling pathway|B cell receptor signalling pathway|B lymphocyte receptor signalling pathway|B lymphocyte receptor signaling pathway A series of molecular signals initiated by the cross-linking of an antigen receptor on a B cell. GO:1902603 carnitine transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902603 The directed movement of carnitine across a membrane. GO:0050854 regulation of antigen receptor-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050854 regulation of antigen receptor mediated signalling pathway Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell. GO:1902604 p-aminobenzoyl-glutamate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902604 N-(4-aminobenzoyl)-L-glutamate transmembrane transport The directed movement of N-(4-aminobenzoyl)-L-glutamate across a membrane. GO:0050859 negative regulation of B cell receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050859 inhibition of B cell receptor signaling pathway|negative regulation of B-lymphocyte receptor signaling pathway|negative regulation of B-cell receptor signalling pathway|negative regulation of B-cell receptor signaling pathway|negative regulation of B-lymphocyte receptor signalling pathway|down regulation of B cell receptor signaling pathway|downregulation of B cell receptor signaling pathway|negative regulation of B cell receptor signalling pathway|negative regulation of B lymphocyte receptor signalling pathway|negative regulation of B lymphocyte receptor signaling pathway|down-regulation of B cell receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell. GO:1902601 silver ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902601 silver transmembrane transport The directed movement of silver ion across a membrane. GO:1902602 aluminum ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902602 aluminum transmembrane transport|aluminium transmembrane transport|aluminium ion transmembrane transport The process in which an aluminium ion is transported across a membrane. CHEBI:86340 L-5-monosubstituted hydantoin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86340 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050857 up regulation of antigen receptor-mediated signaling pathway|activation of antigen receptor-mediated signaling pathway|stimulation of antigen receptor-mediated signaling pathway|up-regulation of antigen receptor-mediated signaling pathway|upregulation of antigen receptor-mediated signaling pathway|positive regulation of antigen receptor mediated signalling pathway Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell. GO:1902600 proton transmembrane transport biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_1902600 hydrogen transport|ATP hydrolysis coupled proton transport|hydrogen ion transport|hydrogen ion transmembrane transport|proton transmembrane transport|passive proton transport, down the electrochemical gradient|hydrogen transmembrane transport|proton transport The directed movement of a proton across a membrane. GO:0050858 negative regulation of antigen receptor-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050858 down-regulation of antigen receptor-mediated signaling pathway|inhibition of antigen receptor-mediated signaling pathway|negative regulation of antigen receptor mediated signalling pathway|down regulation of antigen receptor-mediated signaling pathway|downregulation of antigen receptor-mediated signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell. GO:0050862 positive regulation of T cell receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050862 upregulation of T cell receptor signaling pathway|positive regulation of T-lymphocyte receptor signalling pathway|positive regulation of T lymphocyte receptor signaling pathway|up regulation of T cell receptor signaling pathway|activation of T cell receptor signaling pathway|stimulation of T cell receptor signaling pathway|positive regulation of T cell receptor signalling pathway|positive regulation of T lymphocyte receptor signalling pathway|positive regulation of T-lymphocyte receptor signaling pathway|positive regulation of TCR signaling pathway|up-regulation of T cell receptor signaling pathway|positive regulation of T-cell receptor signaling pathway Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell. GO:0050863 regulation of T cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050863 regulation of T-cell activation|regulation of T lymphocyte activation|regulation of T-lymphocyte activation Any process that modulates the frequency, rate or extent of T cell activation. GO:0050860 negative regulation of T cell receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050860 negative regulation of T-cell receptor signaling pathway|down regulation of T cell receptor signaling pathway|negative regulation of T-lymphocyte receptor signalling pathway|downregulation of T cell receptor signaling pathway|negative regulation of T lymphocyte receptor signaling pathway|negative regulation of T cell receptor signalling pathway|negative regulation of T lymphocyte receptor signalling pathway|down-regulation of T cell receptor signaling pathway|inhibition of T cell receptor signaling pathway|negative regulation of T-lymphocyte receptor signaling pathway|negative regulation of TCR signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell. GO:1902618 cellular response to fluoride biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902618 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoride stimulus. GO:0050861 positive regulation of B cell receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050861 positive regulation of B cell receptor signalling pathway|activation of B cell receptor signaling pathway|stimulation of B cell receptor signaling pathway|positive regulation of B lymphocyte receptor signalling pathway|positive regulation of B-lymphocyte receptor signaling pathway|up-regulation of B cell receptor signaling pathway|positive regulation of B-cell receptor signaling pathway|positive regulation of B-cell receptor signalling pathway|upregulation of B cell receptor signaling pathway|positive regulation of B-lymphocyte receptor signalling pathway|positive regulation of B lymphocyte receptor signaling pathway|up regulation of B cell receptor signaling pathway Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell. GO:1902619 regulation of microtubule minus-end binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902619 Any process that modulates the frequency, rate or extent of microtubule minus-end binding. GO:1902616 acyl carnitine transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902616 O-acylcarnitine transmembrane transport The process in which acyl carnitine is transported across a membrane. GO:0050866 negative regulation of cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050866 down regulation of cell activation|downregulation of cell activation|down-regulation of cell activation|inhibition of cell activation Any process that stops, prevents, or reduces the frequency, rate or extent of cell activation. GO:1902617 response to fluoride biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902617 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoride stimulus. GO:0050867 positive regulation of cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050867 upregulation of cell activation|up regulation of cell activation|activation of cell activation|stimulation of cell activation|up-regulation of cell activation Any process that activates or increases the frequency, rate or extent of activation. GO:1902614 positive regulation of anti-Mullerian hormone signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902614 up regulation of anti-Mullerian hormone signaling pathway|upregulation of anti-Mullerian hormone signaling pathway|up-regulation of anti-Mullerian hormone signaling pathway|activation of anti-Mullerian hormone signaling pathway Any process that activates or increases the frequency, rate or extent of anti-Mullerian hormone signaling pathway. GO:0050864 regulation of B cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050864 regulation of B lymphocyte activation|regulation of B-lymphocyte activation|regulation of B-cell activation Any process that modulates the frequency, rate or extent of B cell activation. GO:1902615 immune response involved in response to exogenous dsRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902615 immune response involved in response to viral dsRNA|immune response involved in response to exogenous double-stranded RNA Any immune response that is involved in response to exogenous dsRNA. GO:0050865 regulation of cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050865 Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand. GO:1902612 regulation of anti-Mullerian hormone signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902612 Any process that modulates the frequency, rate or extent of anti-Mullerian hormone signaling pathway. GO:2001237 negative regulation of extrinsic apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001237 negative regulation of extrinsic apoptosis|negative regulation of extrinsic apoptotic signalling pathway Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway. GO:1902613 negative regulation of anti-Mullerian hormone signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902613 down-regulation of anti-Mullerian hormone signaling pathway|downregulation of anti-Mullerian hormone signaling pathway|down regulation of anti-Mullerian hormone signaling pathway|inhibition of anti-Mullerian hormone signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of anti-Mullerian hormone signaling pathway. GO:2001238 positive regulation of extrinsic apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001238 positive regulation of extrinsic apoptosis|positive regulation of extrinsic apoptotic signalling pathway Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway. GO:0050868 negative regulation of T cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050868 down-regulation of T cell activation|inhibition of T cell activation|negative regulation of T-lymphocyte activation|negative regulation of T-cell activation|down regulation of T cell activation|downregulation of T cell activation|negative regulation of T lymphocyte activation Any process that stops, prevents, or reduces the frequency, rate or extent of T cell activation. GO:2001239 regulation of extrinsic apoptotic signaling pathway in absence of ligand biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001239 regulation of extrinsic apoptotic signalling pathway in absence of ligand|regulation of dependence receptor signaling pathway|regulation of extrinsic apoptosis in absence of ligand Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand. GO:1902610 response to N-phenylthiourea biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902610 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a N-phenylthiourea stimulus. GO:0050869 negative regulation of B cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050869 negative regulation of B-cell activation|down regulation of B cell activation|downregulation of B cell activation|negative regulation of B lymphocyte activation|down-regulation of B cell activation|inhibition of B cell activation|negative regulation of B-lymphocyte activation Any process that stops, prevents, or reduces the frequency, rate or extent of B cell activation. GO:1902611 cellular response to N-phenylthiourea biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902611 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a N-phenylthiourea stimulus. CHEBI:86375 (11Z)-hexadec-11-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86375 CHEBI:86376 (10E,12Z)-hexadecadienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86376 CHEBI:86377 5beta-dihydroepitestosterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86377 CHEBI:86378 (25R)-3beta-hydroxycholest-5-en-26-oic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86378 CHEBI:86379 alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86379 GO:2001230 positive regulation of response to gamma radiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001230 positive regulation of response to gamma ray|positive regulation of response to gamma-ray photon Any process that activates or increases the frequency, rate or extent of response to gamma radiation. GO:2001231 regulation of protein localization to prospore membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001231 regulation of protein targeting to prospore membrane|regulation of protein targeting to forespore membrane|regulation of protein-prospore membrane targeting|regulation of protein localisation to prospore membrane|regulation of protein targeting to ascospore-type prospore membrane|regulation of protein targeting to FSM Any process that modulates the frequency, rate or extent of protein localization to prospore membrane. GO:2001232 positive regulation of protein localization to prospore membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001232 positive regulation of protein targeting to forespore membrane|positive regulation of protein-prospore membrane targeting|positive regulation of protein targeting to FSM|positive regulation of protein localisation to prospore membrane|positive regulation of protein targeting to ascospore-type prospore membrane|positive regulation of protein targeting to prospore membrane Any process that activates or increases the frequency, rate or extent of protein localization to prospore membrane. GO:0098808 mRNA cap binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098808 Interacting selectively and non-covalently with a 7-methylguanosine (m7G) group or derivative located at the 5' end of an mRNA molecule. GO:2001233 regulation of apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001233 regulation of apoptotic signalling pathway Any process that modulates the frequency, rate or extent of apoptotic signaling pathway. GO:2001234 negative regulation of apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001234 negative regulation of apoptotic signalling pathway Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic signaling pathway. GO:0098809 nitrite reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098809 Catalysis of the reaction: nitrite + acceptor = product(s) of nitrate reduction + reduced acceptor. GO:2001235 positive regulation of apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001235 positive regulation of apoptotic signalling pathway Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway. GO:0098806 deadenylation involved in gene silencing by miRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098806 Shortening of the poly(A) tail of a nuclear-transcribed mRNA following miRNA binding to mRNA, resulting in destabilization of the mRNA and a reduction in the efficiency of its translation. GO:2001236 regulation of extrinsic apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001236 regulation of extrinsic apoptotic signalling pathway|regulation of extrinsic apoptosis Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway. GO:0098807 chloroplast thylakoid membrane protein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098807 A protein complex that is part of a chloroplast thylakoid membrane. GO:0098804 non-motile cilium membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098804 nonmotile primary cilium membrane The portion of the plasma membrane surrounding a non-motile cilium. GO:0098805 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0098805 GO:0098802 plasma membrane signaling receptor complex biolink:CellularComponent go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0098802 Any protein complex that is part of the plasma membrane and which functions as a signaling receptor. GO:0098803 respiratory chain complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098803 Any protein complex that is part of a respiratory chain. GO:0098800 inner mitochondrial membrane protein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098800 Any protein complex that is part of the inner mitochondrial membrane. GO:0098801 regulation of renal system process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098801 Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by the renal system. GO:0050873 brown fat cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050873 brown adipocyte differentiation|brown adipocyte cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria. GO:0050874 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050874 GO:0050871 positive regulation of B cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050871 positive regulation of B-lymphocyte activation|up-regulation of B cell activation|positive regulation of B-cell activation|upregulation of B cell activation|positive regulation of B lymphocyte activation|up regulation of B cell activation|activation of B cell activation|stimulation of B cell activation Any process that activates or increases the frequency, rate or extent of B cell activation. GO:1902629 regulation of mRNA stability involved in cellular response to UV biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902629 regulation of mRNA stability involved in cellular response to UV radiation stimulus|regulation of mRNA stability involved in cellular response to ultraviolet light stimulus|regulation of mRNA stability involved in cellular response to ultraviolet radiation stimulus|regulation of mRNA stability involved in cellular response to UV light stimulus Any regulation of mRNA stability that is involved in cellular response to UV. GO:0050872 white fat cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050872 white adipocyte cell differentiation|white adipocyte differentiation The process in which a relatively unspecialized cell acquires specialized features of a white adipocyte, an animal connective tissue cell involved in energy storage. White adipocytes have cytoplasmic lipids arranged in a unique vacuole. GO:1902627 regulation of assembly of large subunit precursor of preribosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902627 regulation of preribosome, large subunit precursor formation|regulation of 66S preribosome formation|regulation of 66S preribosome assembly Any process that modulates the frequency, rate or extent of assembly of a large subunit precursor of preribosome. GO:0050877 nervous system process biolink:BiologicalProcess go-plus goslim_flybase_ribbon|goslim_chembl|goslim_agr|goslim_pir|goslim_generic http://purl.obolibrary.org/obo/GO_0050877 neurological system process|neurophysiological process|pan-neural process A organ system process carried out by any of the organs or tissues of neurological system. GO:1902628 positive regulation of assembly of large subunit precursor of preribosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902628 activation of assembly of large subunit precursor of preribosome|up-regulation of assembly of large subunit precursor of preribosome|up regulation of 66S preribosome formation|upregulation of 66S preribosome assembly|positive regulation of 66S preribosome formation|upregulation of preribosome, large subunit precursor formation|activation of 66S preribosome formation|up-regulation of 66S preribosome assembly|up regulation of assembly of large subunit precursor of preribosome|up-regulation of 66S preribosome formation|activation of preribosome, large subunit precursor formation|up-regulation of preribosome, large subunit precursor formation|activation of 66S preribosome assembly|positive regulation of 66S preribosome assembly|upregulation of assembly of large subunit precursor of preribosome|upregulation of 66S preribosome formation|up regulation of 66S preribosome assembly|positive regulation of preribosome, large subunit precursor formation|up regulation of preribosome, large subunit precursor formation Any process that activates or increases the frequency, rate or extent of assembly of a large subunit precursor of preribosome. GO:0050878 regulation of body fluid levels biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0050878 Any process that modulates the levels of body fluids. GO:1902625 obsolete negative regulation of induction of conjugation with cellular fusion by negative regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902625 OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of induction of conjugation with cellular fusion. GO:0050875 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050875 GO:1902626 assembly of large subunit precursor of preribosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902626 66S preribosome formation|66S preribosome assembly|preribosome, large subunit precursor formation The aggregation, arrangement and bonding together of a set of components to form the large subunit precursor of the preribosome. GO:0050876 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050876 GO:1902623 negative regulation of neutrophil migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902623 down regulation of neutrophil migration|inhibition of neutrophil migration|down-regulation of neutrophil migration|downregulation of neutrophil migration Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil migration. GO:2001248 regulation of ammonia assimilation cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001248 regulation of glutamate metabolic process via glutamine and ammonia|regulation of glutamate metabolism via glutamine and ammonia Any process that modulates the frequency, rate or extent of ammonia assimilation cycle. GO:1902624 positive regulation of neutrophil migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902624 upregulation of neutrophil migration|up-regulation of neutrophil migration|activation of neutrophil migration|up regulation of neutrophil migration Any process that activates or increases the frequency, rate or extent of neutrophil migration. GO:2001249 negative regulation of ammonia assimilation cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001249 negative regulation of glutamate metabolic process via glutamine and ammonia|negative regulation of glutamate metabolism via glutamine and ammonia Any process that stops, prevents or reduces the frequency, rate or extent of ammonia assimilation cycle. GO:0050879 multicellular organismal movement biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0050879 Any physiological process involved in changing the position of a multicellular organism or an anatomical part of a multicellular organism. GO:1902621 actomyosin contractile ring disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902621 CAR disassembly|constriction ring disassembly|contractile actomyosin ring disassembly|cytokinetic ring disassembly|actomyosin ring disassembly The disaggregation of an actomyosin contractile ring into its constituent components. CHEBI:86363 2-dehydro-L-gluconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86363 GO:1902622 regulation of neutrophil migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902622 Any process that modulates the frequency, rate or extent of neutrophil migration. GO:1902620 positive regulation of microtubule minus-end binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902620 upregulation of microtubule minus-end binding|up regulation of microtubule minus-end binding|activation of microtubule minus-end binding|up-regulation of microtubule minus-end binding Any process that activates or increases the frequency, rate or extent of microtubule minus-end binding. GO:0035298 regulation of Malpighian tubule size biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035298 Ensuring that a Malpighian tubule is the correct length and diameter. GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001240 negative regulation of extrinsic apoptosis in absence of ligand|negative regulation of dependence receptor signaling pathway|negative regulation of extrinsic apoptotic signalling pathway in absence of ligand Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand. GO:0035299 inositol pentakisphosphate 2-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035299 RHEA:20313|MetaCyc:RXN-7163|KEGG_REACTION:R05202|Reactome:R-HSA-1855179|Reactome:R-HSA-1855176|EC:2.7.1.158 inositol polyphosphate kinase activity|Ins(1,3,4,5,6)P5 2-kinase activity|inositol-pentakisphosphate 2-kinase activity|Ipk1p|Gsl1p|IP5 2-kinase activity|inositol 1,3,4,5,6-pentakisphosphate 2-kinase activity|ATP:1D-myo-inositol 1,3,4,5,6-pentakisphosphate 2-phosphotransferase activity Catalysis of the reaction: 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ATP = 1D-myo-inositol hexakisphosphate + ADP + 2 H(+). GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001241 positive regulation of extrinsic apoptosis in absence of ligand|positive regulation of dependence receptor signaling pathway|positive regulation of extrinsic apoptotic signalling pathway in absence of ligand Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand. GO:2001242 regulation of intrinsic apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001242 regulation of intrinsic apoptotic pathway|regulation of mitochondrial-mediated apoptotic pathway|regulation of intrinsic apoptotic signalling pathway|regulation of intrinsic apoptosis Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway. GO:2001243 negative regulation of intrinsic apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001243 negative regulation of mitochondrial-mediated apoptotic pathway|negative regulation of intrinsic apoptosis|negative regulation of intrinsic apoptotic signalling pathway|negative regulation of intrinsic apoptotic pathway Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway. GO:0098819 depolarization of postsynaptic membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098819 A process that depolarizes a postsynaptic membrane relative to its resting potential. This has an excitatory effect on the post-synaptic cell, moving the membrane potential towards the firing threshold. GO:2001244 positive regulation of intrinsic apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001244 positive regulation of intrinsic apoptosis|positive regulation of mitochondrial-mediated apoptotic pathway|positive regulation of intrinsic apoptotic pathway|positive regulation of intrinsic apoptotic signalling pathway Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway. GO:2001245 regulation of phosphatidylcholine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001245 regulation of phosphatidylcholine biosynthesis|regulation of phosphatidylcholine anabolism|regulation of phosphatidylcholine synthesis|regulation of phosphatidylcholine formation Any process that modulates the frequency, rate or extent of phosphatidylcholine biosynthetic process. GO:2001246 negative regulation of phosphatidylcholine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001246 negative regulation of phosphatidylcholine biosynthesis|negative regulation of phosphatidylcholine synthesis|negative regulation of phosphatidylcholine formation|negative regulation of phosphatidylcholine anabolism Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylcholine biosynthetic process. GO:0098817 evoked excitatory postsynaptic potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098817 A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell induced by the evoked release of many vesicles of excitatory neurotransmitter at the synapse. GO:2001247 positive regulation of phosphatidylcholine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001247 positive regulation of phosphatidylcholine formation|positive regulation of phosphatidylcholine biosynthesis|positive regulation of phosphatidylcholine anabolism|positive regulation of phosphatidylcholine synthesis Any process that activates or increases the frequency, rate or extent of phosphatidylcholine biosynthetic process. GO:0098818 hyperpolarization of postsynaptic membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098818 A process that hyerpolarizes a postsynaptic membrane relative to its resting potential. This has an inhibitory effect on the post-synaptic cell, moving the membrane potential away from the firing threshold. GO:0035290 trunk segmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035290 Partitioning of the blastoderm embryo into trunk segmental units. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8. GO:0098815 modulation of excitatory postsynaptic potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098815 Any process that modulates the frequency, rate or extent of excitatory postsynaptic potential (EPSP). EPSP is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential. GO:0035291 specification of segmental identity, intercalary segment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035291 The specification of the characteristic structures of the intercalary segment of the anterior head, following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized. GO:0098816 mini excitatory postsynaptic potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098816 A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse. GO:0035292 specification of segmental identity, trunk biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035292 The specification of the characteristic structures of trunk segments, following establishment of segment boundaries. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8. Identity is considered to be the aggregate of characteristics by which a structure is recognized. GO:0098813 nuclear chromosome segregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098813 The process in which genetic material, in the form of nuclear chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. Nuclear chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles. GO:0035293 chitin-based larval cuticle pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035293 The process that gives rise to the patterns of cell differentiation in the chitin-based larval cuticle. An example of this is found in Drosophila melanogaster. GO:0098814 spontaneous synaptic transmission biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098814 basal synaptic transmission The low level of synaptic transmission that occurs via spontaneous neurotransmitter release into the synaptic cleft in the absence of a presynaptic action potential. GO:0098811 obsolete transcriptional repressor activity, RNA polymerase II activating transcription factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098811 RNA polymerase II activating transcription factor binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II transcription repressor activity|RNA polymerase II activating transcription factor binding transcription repressor activity OBSOLETE. Interacting selectively and non-covalently with an RNA polymerase II activating transcription factor and also with the RNA polymerase II basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription. GO:0035294 determination of wing disc primordium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035294 Allocation of embryonic cells to the wing disc founder populations, groups of cells that are committed to contribute to the formation of a wing imaginal disc. GO:0050870 positive regulation of T cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050870 positive regulation of T lymphocyte activation|up regulation of T cell activation|activation of T cell activation|stimulation of T cell activation|positive regulation of T-lymphocyte activation|up-regulation of T cell activation|positive regulation of T-cell activation|upregulation of T cell activation Any process that activates or increases the frequency, rate or extent of T cell activation. GO:0035295 tube development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035295 The process whose specific outcome is the progression of a tube over time, from its initial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts. GO:0098812 nuclear rRNA polyadenylation involved in polyadenylation-dependent rRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098812 nuclear rRNA polyadenylation involved in poly(A)-dependent rRNA catabolic process|nuclear rRNA polyadenylation during polyadenylation-dependent rRNA catabolic process The enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end of a rRNA, occurring as part of the process of polyadenylation-dependent rRNA catabolism in the nucleus. GO:0035296 regulation of tube diameter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035296 Any process that modulates the diameter of a tube. GO:0035297 regulation of Malpighian tubule diameter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035297 Ensuring that the Malpighian tubule is the correct width. Malpighian tubules have a uniform circumference along their length; the circumference of the tubes is eight cells during the time the cells are dividing, after which the cells rearrange producting tubes with a cirumference of two cells. GO:0098810 neurotransmitter reuptake biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098810 The directed movement of neurotransmitter molecules from the extrasynaptic space into the presynaptic cytosol. GO:0050884 neuromuscular process controlling posture biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050884 regulation of posture Any process in which an organism voluntarily modulates its posture, the alignment of its anatomical parts. GO:0050885 neuromuscular process controlling balance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050885 regulation of balance Any process that an organism uses to control its balance, the orientation of the organism (or the head of the organism) in relation to the source of gravity. In humans and animals, balance is perceived through visual cues, the labyrinth system of the inner ears and information from skin pressure receptors and muscle and joint receptors. GO:0050882 voluntary musculoskeletal movement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050882 The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system that can be controlled at will. GO:0050883 musculoskeletal movement, spinal reflex action biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050883 Involuntary movement caused by the application of a stimulus to an organism and a subsequent movement. The signal processing of this movement takes place in the spinal cord. GO:1902638 neural crest cell differentiation involved in parathyroid gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902638 Any neural crest cell differentiation that is involved in parathyroid gland development. GO:0050888 determination of stimulus location biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050888 The determination of where on the body surface, within the body or in the environment a stimulus originates. GO:1902639 propan-2-ol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902639 Isopropyl alcohol metabolic process|propan-2-ol metabolism|Isopropanol metabolic process The chemical reactions and pathways involving propan-2-ol. GO:0050889 determination of stimulus intensity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050889 The determination of the perceived strength of a sensory stimulus. GO:1902636 kinociliary basal body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902636 cilial basal body of kinocilium|kinocilium basal body|microtubule basal body of kinocilium|kinocilium ciliary basal body|cilium basal body of kinocilium|kinocilial basal body|ciliary basal body of kinocilium A ciliary basal body that is part of a kinocilium. GO:0050886 endocrine process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0050886 endocrine physiological process|endocrine physiology The process that involves the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system. CHEBI:86392 4-guanidinobutanoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86392 GO:1902637 neural crest cell differentiation involved in thymus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902637 Any neural crest cell differentiation that is involved in thymus development. GO:0050887 determination of sensory modality biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050887 The determination of the type or quality of a sensation. Sensory modalities include touch, thermal sensation, visual sensation, auditory sensation and pain. GO:1902634 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902634 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism The chemical reactions and pathways resulting in the breakdown of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate. GO:2001259 positive regulation of cation channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001259 positive regulation of nonselective cation channel activity|positive regulation of cation diffusion facilitator activity Any process that activates or increases the frequency, rate or extent of cation channel activity. CHEBI:86394 5-aminopentanoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86394 GO:1902635 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902635 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis The chemical reactions and pathways resulting in the formation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate. GO:1902632 positive regulation of membrane hyperpolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902632 upregulation of membrane hyperpolarization|up-regulation of membrane hyperpolarization|activation of membrane hyperpolarization|up regulation of membrane hyperpolarization Any process that activates or increases the frequency, rate or extent of membrane hyperpolarization. GO:1902633 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902633 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolism The chemical reactions and pathways involving 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate. GO:1902630 regulation of membrane hyperpolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902630 Any process that modulates the frequency, rate or extent of membrane hyperpolarization. GO:1902631 negative regulation of membrane hyperpolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902631 downregulation of membrane hyperpolarization|down regulation of membrane hyperpolarization|inhibition of membrane hyperpolarization|down-regulation of membrane hyperpolarization Any process that stops, prevents or reduces the frequency, rate or extent of membrane hyperpolarization. CHEBI:86399 (4R,6R)-hydroxy-2,2,6-trimethylcyclohexanone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86399 GO:2001251 negative regulation of chromosome organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001251 negative regulation of chromosome organization and biogenesis|negative regulation of chromosome organisation|negative regulation of nuclear genome maintenance|negative regulation of maintenance of genome integrity Any process that stops, prevents or reduces the frequency, rate or extent of chromosome organization. GO:0060210 metestrus biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0060210 The estrous cycle phase in which there is subsiding follicular function. GO:0035287 head segmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035287 Partitioning the insect head anlage into a fixed number of segmental units. The number of segments composing the insect head has long been a subject of debate, but it is generally agreed that there are 6 or 7 segments. From anterior to posterior the head segments are the procephalic segments (labral, (ocular), antennal and intercalary) and the gnathal segments (mandibular, maxillary and labial). GO:2001252 positive regulation of chromosome organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001252 positive regulation of chromosome organisation|positive regulation of chromosome organization and biogenesis|positive regulation of maintenance of genome integrity|positive regulation of nuclear genome maintenance Any process that activates or increases the frequency, rate or extent of chromosome organization. GO:0035288 anterior head segmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035288 procephalic segmentation Partitioning the insect head anlage into procephalic (labral, (ocular), antennal and intercalary) segments. The procephalic segments lie anterior to the gnathal (posterior head) segments, and are pattered by different segmentation gene cascades to the abdominal, thoracic and posterior head (gnathal) segments. GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060211 regulation of mRNA deadenylation|regulation of nuclear mRNA poly(A) tail shortening|regulation of 3' to 5' mRNA deadenylation Any process that modulates the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length. GO:0035289 posterior head segmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035289 gnathal segmentation Partitioning the posterior region of the insect head anlage into gnathal (mandibular, maxillary and labial) segments. Unlike the anterior head (procephalic) segments, formation of the posterior head (gnathal) segments occurs by a similar mechanism to trunk segmentation, where a cascade of gap genes, pair-rule genes and segment-polarity genes subdivide the embryo into progressively smaller domains. GO:2001253 regulation of histone H3-K36 trimethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001253 Any process that modulates the frequency, rate or extent of histone H3-K36 trimethylation. GO:0060212 negative regulation of nuclear-transcribed mRNA poly(A) tail shortening biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060212 negative regulation of nuclear mRNA poly(A) tail shortening|negative regulation of mRNA deadenylation|negative regulation of 3' to 5' mRNA deadenylation Any process that decreases the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length. GO:2001254 negative regulation of histone H3-K36 trimethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001254 Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K36 trimethylation. GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060213 positive regulation of nuclear mRNA poly(A) tail shortening|positive regulation of 3' to 5' mRNA deadenylation|positive regulation of mRNA deadenylation Any process that increases the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length. GO:2001255 positive regulation of histone H3-K36 trimethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001255 Any process that activates or increases the frequency, rate or extent of histone H3-K36 trimethylation. GO:0060214 endocardium formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060214 Formation of the endocardium of the heart. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. GO:2001256 regulation of store-operated calcium entry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001256 regulation of calcium ion import|regulation of store-operated calcium import|regulation of capacitative calcium entry|regulation of SOCE Any process that modulates the frequency, rate or extent of store-operated calcium entry. GO:0060215 primitive hemopoiesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060215 primitive haematopoiesis|primitive hematopoiesis|primitive haemopoiesis A first transient wave of blood cell production that, in vertebrates, gives rise to erythrocytes (red blood cells) and myeloid cells. GO:2001257 regulation of cation channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001257 regulation of nonselective cation channel activity|regulation of cation diffusion facilitator activity Any process that modulates the frequency, rate or extent of cation channel activity. GO:0060216 definitive hemopoiesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060216 definitive haematopoiesis|definitive hematopoiesis|definitive haemopoiesis A second wave of blood cell production that, in vertebrates, generates long-term hemopoietic stem cells that continously provide erythroid, myeloid and lymphoid lineages throughout adulthood. GO:2001258 negative regulation of cation channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001258 negative regulation of cation diffusion facilitator activity|negative regulation of nonselective cation channel activity Any process that stops, prevents or reduces the frequency, rate or extent of cation channel activity. GO:0060217 hemangioblast cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060217 The process in which a relatively unspecialized cell acquires the characteristics of a mature hemangioblast. Hemangioblasts are the proposed common precursor of blood and endothelial lineages. GO:0060218 hematopoietic stem cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060218 haemopoietic stem cell differentiation|haematopoietic stem cell differentiation|hemopoietic stem cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a hematopoietic stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. GO:0060219 camera-type eye photoreceptor cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060219 The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell in a camera-type eye. GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035280 miRISC assembly|gene silencing by miRNA, miRNA loading onto RISC|miRNA-mediated gene silencing, miRNA loading onto RISC|microRNA loading onto RISC involved in gene silencing by microRNA The transfer of a microRNA (miRNA) strand from a miRNA:miRNA duplex onto the RNA-initiated silencing complex (RISC). GO:0035281 pre-miRNA export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035281 pre-microRNA-nucleus export|pre-microRNA transport from nucleus to cytoplasm|pre-microRNA export from cell nucleus|pre-microRNA export out of nucleus|pre-microRNA export from nucleus Transport of pre-microRNAs (pre-miRNAs) from the nucleus to the cytoplasm. Pre-miRNAs are a ~60-70 nucleotide stem loop intermediate in miRNA production, produced by the nuclear cleavage of a primary miRNA (pri-mRNA) transcript. Pre-miRNAs are transported from the nucleus to the cytoplasm where further cleavage occurs to produce a mature miRNA product. GO:0035282 segmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035282 Wikipedia:Segmentation_(biology) The regionalization process that divides an organism or part of an organism into a series of semi-repetitive parts, or segments, often arranged along a longitudinal axis. GO:0035283 central nervous system segmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035283 Division of the central nervous system into a series of semi-repetitive parts or segments. GO:0050880 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050880 GO:0050881 musculoskeletal movement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050881 The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system. GO:0035284 brain segmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035284 Division of the brain into a series of semi-repetitive parts or segments. GO:0035285 appendage segmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035285 Division of an appendage, an organ or part that is attached to the main body of an organism, into a series of semi-repetitive parts or segments. Most arthropod appendages, such as the legs and antennae, are visibly segmented. GO:0035286 obsolete leg segmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035286 leg segmentation OBSOLETE. Division of a leg into a series of semi-repetitive parts or segments. Most arthropod appendages are visibly segmented; the Drosophila leg for example has nine segments, each separated from the next by a flexible joint. GO:2001250 positive regulation of ammonia assimilation cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001250 positive regulation of glutamate metabolic process via glutamine and ammonia|positive regulation of glutamate metabolism via glutamine and ammonia Any process that activates or increases the frequency, rate or extent of ammonia assimilation cycle. GO:0050895 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0050895 GO:0050896 response to stimulus biolink:BiologicalProcess go-plus goslim_mouse|goslim_agr|gocheck_do_not_manually_annotate|goslim_pir|goslim_flybase_ribbon http://purl.obolibrary.org/obo/GO_0050896 physiological response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. GO:0050893 sensory processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050893 Any neural process required for an organism to sense and interpret the dimensions of a sensory experience: modality, location, intensity and affect. GO:0050894 determination of affect biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050894 Any process in which an emotional response is associated with a particular sensory stimulation. GO:0050899 nitrile catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050899 nitrile degradation|nitrile breakdown|nitrile catabolism The chemical reactions and pathways resulting in the breakdown of a nitrile, an organic compound containing trivalent nitrogen attached to one carbon atom. GO:1902649 regulation of histone H2A-H2B dimer displacement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902649 Any process that modulates the frequency, rate or extent of histone H2A-H2B dimer displacement. GO:1902647 negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902647 down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process|negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process|inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process|down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process|inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis Any process that stops, prevents or reduces the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process. CHEBI:86381 5beta-dihydrocorticosterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86381 GO:0050897 cobalt ion binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050897 cobalt binding Interacting selectively and non-covalently with a cobalt (Co) ion. GO:1902648 positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902648 upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process|activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process|positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process|up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process|upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis Any process that activates or increases the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process. CHEBI:86382 alpha-Kdo-(2->8)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86382 GO:0050898 nitrile metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050898 nitrile metabolism The chemical reactions and pathways involving nitriles, an organic compound containing trivalent nitrogen attached to one carbon atom. The nitriles are named with reference to the acids produced by their decomposition; for example, hydrocyanic acid is formic nitrile, and methyl cyanide is acetic nitrile. GO:1902645 tertiary alcohol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902645 tertiary alcohol anabolism|tertiary alcohol synthesis|tertiary alcohol formation|tertiary alcohol biosynthesis The chemical reactions and pathways resulting in the formation of tertiary alcohol. CHEBI:86384 5beta-dihydrodeoxycorticosterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86384 GO:1902646 regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902646 regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism Any process that modulates the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process. GO:1902643 positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902643 up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process|positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process|up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process|activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process|up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism Any process that activates or increases the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process. CHEBI:86386 3-mercaptopropionate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86386 GO:1902644 tertiary alcohol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902644 tertiary alcohol metabolism The chemical reactions and pathways involving tertiary alcohol. GO:1902641 regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902641 regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown Any process that modulates the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process. GO:1902642 negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902642 down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process|inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process|down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process|negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process|down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation Any process that stops, prevents or reduces the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process. CHEBI:86389 5beta-dihydroaldosterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86389 GO:1902640 propan-2-ol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902640 propan-2-ol formation|propan-2-ol biosynthesis|Isopropyl alcohol biosynthetic process|propan-2-ol anabolism|Isopropanol biosynthetic process|propan-2-ol synthesis The chemical reactions and pathways resulting in the formation of propan-2-ol. GO:2001262 positive regulation of semaphorin-plexin signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001262 positive regulation of semaphorin-plexin signalling pathway Any process that activates or increases the frequency, rate or extent of semaphorin-plexin signaling pathway. GO:0035276 ethanol binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035276 Interacting selectively and non-covalently with ethanol, CH(3)-CH(2)-OH. GO:0060200 clathrin-sculpted acetylcholine transport vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0060200 clathrin sculpted acetylcholine transport vesicle|clathrin sculpted acetylcholine constitutive secretory pathway transport vesicle A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing acetylcholine. GO:2001263 regulation of C-C chemokine binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001263 Any process that modulates the frequency, rate or extent of C-C chemokine binding. GO:0035277 spiracle morphogenesis, open tracheal system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035277 spiracle morphogenesis The process in which the anatomical structures of a spiracle are generated and organized. Spiracles are the openings in the insect open tracheal system; externally they connect to the epidermis and internally they connect to the tracheal trunk. GO:0060201 clathrin-sculpted acetylcholine transport vesicle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0060201 clathrin sculpted acetylcholine transport vesicle membrane|clathrin sculpted acetylcholine constitutive secretory pathway transport vesicle membrane The lipid bilayer surrounding a clathrin-sculpted acetylcholine transport vesicle. GO:0035278 miRNA mediated inhibition of translation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035278 inhibition of translation involved in gene silencing by miRNA|gene silencing by miRNA, negative regulation of translation|miRNA-mediated gene silencing, negative regulation of translation|down regulation of translation involved in gene silencing by miRNA|downregulation of translation involved in gene silencing by miRNA|negative regulation of translation involved in gene silencing by microRNA|down-regulation of translation involved in gene silencing by miRNA The process in which microRNAs (miRNAs) block the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically mediate repression of translation if the miRNA imperfectly base-pairs with the 3' untranslated regions of target mRNAs. GO:2001264 negative regulation of C-C chemokine binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001264 Any process that stops, prevents or reduces the frequency, rate or extent of C-C chemokine binding. GO:2001265 positive regulation of C-C chemokine binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001265 Any process that activates or increases the frequency, rate or extent of C-C chemokine binding. GO:0060202 clathrin-sculpted acetylcholine transport vesicle lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0060202 clathrin sculpted acetylcholine constitutive secretory pathway transport vesicle lumen|clathrin sculpted acetylcholine transport vesicle lumen The volume enclosed by the membrane of the clathrin-sculpted acetylcholine transport vesicle. GO:0035279 mRNA cleavage involved in gene silencing by miRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035279 gene silencing by miRNA, mRNA cleavage|miRNA-mediated gene silencing, mRNA cleavage|mRNA cleavage involved in gene silencing by microRNA The process in which microRNAs (miRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA base pairing with near-perfect complementarity to the target mRNA will typically direct targeted endonucleolytic cleavage of the mRNA. Many plant miRNAs downregulate gene expression through this mechanism. GO:2001266 Roundabout signaling pathway involved in axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001266 Roundabout signaling pathway involved in axon chemotaxis|Roundabout signaling pathway involved in axon pathfinding|Roundabout signalling pathway involved in axon pathfinding|ROBO/SLIT signaling pathway involved in axon pathfinding|ROBO signaling pathway involved in axon guidance|ROBO signaling pathway involved in axon pathfinding|ROBO/SLIT signaling pathway involved in axon guidance|ROBO signaling pathway involved in axon growth cone guidance|ROBO/SLIT signaling pathway involved in axon growth cone guidance|Roundabout signalling pathway involved in axon guidance|Roundabout signalling pathway involved in axon growth cone guidance|ROBO signaling pathway involved in axon chemotaxis|ROBO/SLIT signaling pathway involved in axon chemotaxis|Roundabout signaling pathway involved in axon growth cone guidance|Roundabout signalling pathway involved in axon chemotaxis Any Roundabout signaling pathway that is involved in axon guidance. GO:0060203 clathrin-sculpted glutamate transport vesicle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0060203 clathrin sculpted glutamate transport vesicle membrane|clathrin sculpted glutamate constitutive secretory pathway transport vesicle membrane The lipid bilayer surrounding a clathrin-sculpted glutamate transport vesicle. GO:0060204 clathrin-sculpted glutamate transport vesicle lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0060204 clathrin sculpted glutamate transport vesicle lumen|clathrin sculpted glutamate constitutive secretory pathway transport vesicle lumen The volume enclosed by the membrane of the clathrin-sculpted glutamate transport vesicle. GO:2001267 regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001267 regulation of initiator caspase activity|regulation of cysteine-type endopeptidase activity involved in apoptotic signalling pathway Any process that modulates the frequency, rate or extent of cysteine-type endopeptidase activity involved in apoptotic signaling pathway. GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signalling pathway|negative regulation of initiator caspase activity Any process that stops, prevents or reduces the frequency, rate or extent of cysteine-type endopeptidase activity involved in apoptotic signaling pathway. GO:0060205 cytoplasmic vesicle lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0060205 cytoplasmic membrane-enclosed vesicle lumen|cytoplasmic membrane-bounded vesicle lumen The volume enclosed by a cytoplasmic vesicle. GO:0060206 estrous cycle phase biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0060206 The progression of physiological phases, occurring in the endometrium during the estrous cycle that recur at regular intervals during the reproductive years. The estrous cycle is an ovulation cycle where the endometrium is resorbed if pregnancy does not occur. GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signalling pathway|positive regulation of initiator caspase activity Any process that activates or increases the frequency, rate or extent of cysteine-type endopeptidase activity involved in apoptotic signaling pathway. GO:0060207 diestrus biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0060207 The estrous cycle phase which is a period of sexual quiescence and represents the phase of the mature corpus luteum. GO:0060208 proestrus biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0060208 The estrous cycle phase in which there is heightened follicular activity. GO:0060209 estrus biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0060209 oestrus The estrous cycle phase in which a female is sexually receptive. GO:0035270 endocrine system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035270 Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include the ovaries and testes. GO:0035271 ring gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035271 Progression of the ring gland over time, from its formation to a mature structure. The ring gland is a neuroendocrine organ found in higher Dipterans, which is composed of the prothoracic gland, the corpus allatum, and the corpora cardiacum. The ring gland is the site of production and release of ecdysteroids and juvenile hormones. GO:0050891 multicellular organismal water homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050891 body fluid osmoregulation Any process involved in the maintenance of an internal steady state of water within a tissue, organ, or a multicellular organism. GO:0035272 exocrine system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035272 Progression of the exocrine system over time, from its formation to a mature structure. The exocrine system is a system of hormones and glands, where the glands secrete straight to a target site via ducts or tubes. The human exocrine system includes the salivary glands, sweat glands and many glands of the digestive system. GO:0050892 intestinal absorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050892 Any process in which nutrients are taken up from the contents of the intestine. GO:0035273 phthalate binding biolink:MolecularActivity go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0035273 Interacting selectively and non-covalently with a phthalate, any ester or salt of phthalic acid. GO:0035274 diphenyl phthalate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035274 DPP binding Interacting selectively and non-covalently with diphenyl phthalate, C(20)H(14)O(4). GO:2001260 regulation of semaphorin-plexin signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001260 regulation of semaphorin-plexin signalling pathway Any process that modulates the frequency, rate or extent of semaphorin-plexin signaling pathway. GO:0035275 dibutyl phthalate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035275 DBP binding|phthalic acid dibutyl ester binding Interacting selectively and non-covalently with dibutyl phthalate, C(16)H(22)O(4). GO:0050890 cognition biolink:BiologicalProcess go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0050890 Wikipedia:Cognition The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory. GO:2001261 negative regulation of semaphorin-plexin signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001261 negative regulation of semaphorin-plexin signalling pathway Any process that stops, prevents or reduces the frequency, rate or extent of semaphorin-plexin signaling pathway. CHEBI:76922 argemonine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76922 CHEBI:76921 pavine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76921 CHEBI:27995 3-methylbenzyl alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27995 CHEBI:27996 (R)-4-hydroxymandelate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27996 CHEBI:76924 plant metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76924 CHEBI:27997 elaidic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27997 CHEBI:27998 tungsten biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27998 CHEBI:27991 benzonitrile biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27991 CHEBI:76928 2,3-saturated fatty acid(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76928 CHEBI:27993 1,2-di-O-sinapoyl-beta-D-glucose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27993 CHEBI:27994 luteolin 7-O-beta-D-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27994 CHEBI:76929 2,3-saturated fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76929 CHEBI:37318 2-oxopent-4-enoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37318 CHEBI:37319 2-hydroxypenta-2,4-dienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37319 CHEBI:37316 (E,E)-piperic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37316 CHEBI:13346 Glu-tRNA(Glx) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_13346 UBERON:0000344 mucosa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000344 organ mucosa|mucosa of organ part|mucosal region|mucosa of organ|tunica mucosa|mucous membrane|region of mucosa A lining of mostly endodermal origin, covered in epithelium, which is involved in absorption and secretion. They line various body cavities that are exposed to the external environment and internal organs. It is at several places continuous with skin: at the nostrils, the lips, the ears, the genital area, and the anus. The sticky, thick fluid secreted by the mucous membranes and gland is termed mucus. The term mucous membrane refers to where they are found in the body and not every mucous membrane secretes mucus[WP] CHEBI:76933 3,18-dihydroxyoctadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76933 CHEBI:76934 3,12-dihydroxylauric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76934 CHEBI:76931 Ac-Asp-Glu(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76931 CHEBI:76932 pathway inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76932 UBERON:0000325 gastric gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000325 The branched tubular glands found in the mucosa of the fundus and body of the stomach which contain parietal cells that secrete hydrochloric acid and zymogenic cells that produce pepsin. CHEBI:76937 11-hydroxylauric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76937 UBERON:0000326 pancreatic juice biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000326 pancreatic secretion|pancreatic fluid|succus pancreaticus Pancreatic juice is slightly alkaline and contains numerous enzymes and inactive enzyme precursors including alpha-amylase, chymotrypsinogen, lipase, procarboxypeptidase, proelastase, prophospholipase A2, ribonuclease, and trypsinogen. Its high concentration of bicarbonate ions helps to neutralize the acid from the stomach. CHEBI:76938 EC 3.6.4.* (hydrolases acting on ATP; involved in cellular and subcellular movement) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76938 CHEBI:76935 Ac-Asp-Glu-Glu(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76935 UBERON:0000328 gut wall biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000328 wall of digestive tract|wall of gut|wall of alimentary tract|digestive tract wall The wall of the digestive tract. This encompasses all parts of the digestive tract with the exception of the lumen (cavity). CHEBI:76939 EC 3.6.4.10 (non-chaperonin molecular chaperone ATPase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76939 CHEBI:37325 alloxazine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37325 CHEBI:37326 benzo[g]pteridine-2,4-dione biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37326 CHEBI:37323 7,8-dimethylisoalloxazine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37323 CHEBI:37324 7,8-dimethylbenzo[g]pteridine-2,4-dione biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37324 CHEBI:13332 GDP-beta-L-fucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_13332 CHEBI:37329 phosphatidylinositol 5-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37329 CHEBI:37327 isoalloxazine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37327 CHEBI:37328 phosphatidylinositol bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37328 UBERON:0000332 yellow bone marrow biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000332 medulla ossium flava|fat marrow|yellow marrow bone marrow in which the fat cells predominate in the meshes of the reticular network. UBERON:0000333 intestinal gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000333 bowel mucous membrane gland|glandulae intestinales|gland of mucosa of intestine|gland of intestine organ mucosa|bowel mucosa gland|gland of mucous membrane of bowel|intestine mucosa of organ gland|organ mucosa of intestine gland|gland of intestinal mucosa|gland of mucosa of organ of bowel|intestine mucous membrane gland|gland of bowel mucosa of organ|gland of organ mucosa of bowel|gland of bowel organ mucosa|intestine organ mucosa gland|gland of mucous membrane of intestine|glandula intestinalis|mucous membrane of bowel gland|mucosa of bowel gland|gland of bowel mucous membrane|gland of mucosa of organ of intestine|gland of organ mucosa of intestine|gland of intestine mucosa|mucosa of organ of bowel gland|gland of intestine mucosa of organ|bowel organ mucosa gland|mucous membrane of intestine gland|mucosa of intestine gland|gland of intestine mucous membrane|intestinal mucosa gland|mucosa of organ of intestine gland|gland of bowel mucosa|intestine mucosa gland|gland of mucosa of bowel|bowel mucosa of organ gland|organ mucosa of bowel gland A gland that is part of the intestinal mucosa. Examples include the intestinal crypts, duodenal gland[cjm]. CHEBI:37322 penta-2,4-dienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37322 CHEBI:76930 omega-hydroxytetracosanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76930 CHEBI:76944 13-epi-manool biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76944 CHEBI:27977 erythronolide B biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27977 CHEBI:76945 manool biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76945 CHEBI:27978 3,4-dihydroxyphenylacetaldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27978 CHEBI:76942 beta-citrylglutamate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76942 CHEBI:27979 all-cis-icosa-8,11,14-trienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27979 CHEBI:76943 (+)-copalol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76943 UBERON:0000314 cecum mucosa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000314 mucosa of intestinum crassum caecum|mucosa of organ of cecum|mucosa of organ of intestinum crassum caecum|mucosa of organ of caecum|mucosa of caecum|cecum mucosa of organ|organ mucosa of cecum|mucous membrane of caecum|caecum organ mucosa|organ mucosa of intestinum crassum caecum|intestinum crassum caecum mucosa of organ|intestinum crassum caecum organ mucosa|caecum mucosa of organ|cecum mucous membrane|cecum organ mucosa|intestinum crassum caecum mucous membrane|cecal mucosa|caecum mucous membrane|mucous membrane of cecum|organ mucosa of caecum|mucosa of cecum|caecum mucosa|intestinum crassum caecum mucosa|mucous membrane of intestinum crassum caecum A mucosa that is part of a cecum [Automatically generated definition]. CHEBI:27973 D-arabino-hex-3-ulose 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27973 CHEBI:76948 ent-manool biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76948 UBERON:0000315 subarachnoid space biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000315 spatium leptomeningeum|subarachnoid cavity|spatium subarachnoideum|cavitas subarachnoidea|cavum subarachnoideale The space between the arachnoid and pia mater. CHEBI:27974 estriol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27974 UBERON:0000316 cervical mucus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000316 cervix mucus A substance produced by the cervix and endocervical glands[BTO]. Thick acidic mucus that blocks the cervical os after mestruation[WP]. This 'infertile' mucus blocks spermatozoa from entering the uterus. CHEBI:27975 L-glyceraldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27975 CHEBI:76946 fungal metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76946 UBERON:0000317 colonic mucosa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000317 colonic mucosa|colon mucosa|mucosa of large bowel|colon mucous membrane|colonic mucous membrane|large bowel mucosa|mucosa of colon Mucosa that is part of a colon. The mucosa of the colon is lined by a simple columnar epithelium with a thin brush border and numerous goblet cells. CHEBI:27976 prop-2-ynal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27976 CHEBI:27972 2-deoxy-D-gluc-5-ulosonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27972 UBERON:0000323 late embryo biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000323 fetus|embryo late stage|embryo late growth stage An embryo that is at the late embryonic stage; this stage covers late steps of the embryogenesis with a fully formed embryo still developing before birth or egg hatching. CHEBI:76941 sphingoid 1-phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76941 UBERON:0000320 duodenal mucosa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000320 duodenum mucosa|doudenal mucosa|mucosa of duodenum|mucous membrane of duodenum|duodenal mucous membrane A mucosa that is part of a duodenum [Automatically generated definition]. UBERON:0000307 blastula biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000307 blastula embryo|blastosphere Organism at the blastula stage - an early stage of embryonic development in animals. It is produced by cleavage of a fertilized ovum and consists of a spherical layer of around 128 cells surrounding a central fluid-filled cavity called the blastocoel. The blastula follows the morula and precedes the gastrula in the developmental sequence. CHEBI:76955 17(S),18(R)-EETeTr biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76955 CHEBI:27989 cis-dodec-3-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27989 CHEBI:76956 Aspergillus metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76956 UBERON:0000309 body wall biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000309 trunk wall|wall fo trunk|wall of trunk The external portion of an animal body derived from ectoderm and mesoderm layers that encloses the body cavity. CHEBI:76953 17(R),18(S)-EETeTr biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76953 CHEBI:76954 (13S)-vitexifolin A biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76954 CHEBI:76959 19-HEPE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76959 UBERON:0000304 tendon sheath biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000304 vagina tendinis|synovial tendon sheath A layer of membrane around a tendon. It has 2 layers: synovial sheath + fibrous tendon sheath CHEBI:27986 nitrosobenzene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27986 UBERON:0014950 layer of developing cerebral cortex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014950 CHEBI:62318 D-lyxose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62318 UBERON:0000310 breast biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000310 mamma|mammary region|mammary part of chest The upper ventral region of the torso of an organism. UBERON:0000313 portion of cartilage tissue in tibia biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000313 tibial cartilage|cartilage of tibia Cartilage pertaining to the tibia. CHEBI:76952 syn-copalol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76952 CHEBI:76950 (-)-ent-copalol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76950 CHEBI:27955 streptamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27955 CHEBI:76966 (5Z,8Z,11Z,14Z)-icosatetraenedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76966 CHEBI:76967 human xenobiotic metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76967 CHEBI:27956 L-dehydroascorbic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27956 CHEBI:76964 Penicillium metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76964 CHEBI:27957 hydroxyacetone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27957 CHEBI:76965 20-oxoarachidonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76965 CHEBI:27958 cocaine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27958 CHEBI:27951 (R)-3-hydroxy-2-oxo-4-phosphonooxybutanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27951 CHEBI:76968 fungal xenobiotic metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76968 CHEBI:76969 bacterial metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76969 PO:0000207 nectary epidermis biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000207 蜜腺表皮 (Japanese, exact)|epidermis del nectario (Spanish, exact) A portion of shoot system epidermis (PO:0006035) that is part of a nectary (PO:0009035) . CHEBI:52915 phosphatediyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52915 CHEBI:62320 L-lyxose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62320 GO:2001075 negative regulation of metanephric ureteric bud development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001075 Any process that stops, prevents or reduces the frequency, rate or extent of metanephric ureteric bud development. GO:2001076 positive regulation of metanephric ureteric bud development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001076 Any process that activates or increases the frequency, rate or extent of metanephric ureteric bud development. GO:2001077 (1->3),(1->4)-beta-glucan binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_2001077 beta-(1->3),(1->4)-glucan binding|1->3,1->4-beta-glucan binding|beta-1->3,1->4-glucan binding|(1,3),(1,4)-beta-glucan binding|beta-1,3-1,4-glucan binding|beta-(1,3),(1,4)-glucan binding Interacting selectively and non-covalently with (1->3),(1->4)-beta-glucan. GO:2001078 (1->6)-beta-D-glucan binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_2001078 beta-(1,6)-D-glucan binding|beta-1,6-D-glucan binding|1,6-beta-D-glucan binding|(1,6)-beta-D-glucan binding|1->6-beta-D-glucan binding|beta-(1->6)-D-glucan binding|beta-1->6-D-glucan binding Interacting selectively and non-covalently with (1->6)-beta-D-glucan. UBERON:0000382 apocrine sweat gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000382 glandula sudorifera apocrina Apocrine sweat glands are sweat glands composed of a coiled secretory portion located at the junction of the dermis and subcutaneous fat, from which a straight portion inserts and secretes into the infundibular portion of the hair follicle. The ducts of apocrine glands open into the canals of hair follicles. The stimulus for the secretion of apocrine sweat glands is adrenaline, which is a hormone carried in the blood[WP]. CHEBI:62324 D-mannosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62324 GO:2001079 beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_2001079 Interacting selectively and non-covalently with beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc. CHEBI:62327 alpha-D-Galp-(1->3)-beta-D-Galp-(1->4)-beta-D-GlcpNAc biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62327 UBERON:0000389 lens cortex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000389 cortex of lens Tissue that surrounds the lens nucleus GO:2001070 starch binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_2001070 amylum binding|amidon binding Interacting selectively and non-covalently with starch. UBERON:0000383 musculature of body biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000383 musculature system|muscle system of body|set of muscles of body|muscle system|vertebrate muscular system|set of all muscles|muskelsystem|muscular system The subdivision of the musculoskeletal system that consists of all the muscles of the body[VSAO, modified]. GO:2001071 maltoheptaose binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_2001071 Interacting selectively and non-covalently with maltoheptaose. CHEBI:76962 20-HEPE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76962 GO:2001072 galactomannan binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_2001072 Interacting selectively and non-covalently with galactomannan. GO:2001073 cyclodextrin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_2001073 Interacting selectively and non-covalently with cyclodextrin. GO:2001074 regulation of metanephric ureteric bud development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001074 Any process that modulates the frequency, rate or extent of metanephric ureteric bud development. CHEBI:27967 11beta-hydroxyandrost-4-ene-3,17-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27967 CHEBI:76978 trioctanoin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76978 CHEBI:76976 bacterial xenobiotic metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76976 CHEBI:27969 mesaconyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27969 UBERON:0000369 corpus striatum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000369 striated body|striate body The corpus striatum (striated body) is a compound structure consisting of the caudate nucleus and the lentiform nucleus, which consists of the putamen and the globus pallidus[WP]. CHEBI:27962 pent-2-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27962 CHEBI:27963 (Kdo)2-lipid A (E. coli) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27963 CHEBI:27964 5-methyldeoxycytidine 5'-(trihydrogen diphosphate) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27964 CHEBI:76979 1,2-dioctanoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76979 CHEBI:27961 1,8-cineole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27961 GO:2001086 laminarabiose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001086 The directed movement of a laminarabioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:2001087 sophorose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001087 The directed movement of a sophoroseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:2001088 trisaccharide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001088 The directed movement of a trisaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:2001089 maltotriose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001089 The directed movement of a maltotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:62338 O(4)-phosphonato-L-tyrosine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62338 UBERON:0000376 hindlimb stylopod biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000376 hind propodium|hindlimb stylopodium|stylopod of hindlimb|thigh|hind limb stylopodium|hindlimb propodium|upper leg|hind limb stylopod|proximal segment of free lower limb|stylopod of hind limb|femur|stylopod of lower limb|hindlimb stylopod The part of the hindlimb between pelvis and the knee, corresponding to the femur. UBERON:0000377 maxillary nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000377 second division of trigeminal nerve|nervus maxillaris [v2]|ramus maxillaris (ramus V2)|maxillary division [V2]|n. maxillaris|maxillary nerve [V2]|second division of fifth cranial nerve|trigeminal V nerve maxillary division|nervus maxillaris [vb]|nervus maxillaris (Vb; V2)|maxillary division [Vb]|maxillary nerve [Vb]|trigeminal nerve maxillary division|maxillary division of fifth cranial nerve|maxillary division of trigeminal nerve (Vb; V2)|nervus maxillaris The sensory nerve subdivision of the trigeminal nerve that transmits sensory information from the palate, upper teeth and gingiva, the skin between the palpebral fissure and the mouth, and from the nasal cavity and maxillary sinuses. UBERON:0000378 tongue muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000378 muscle of tongue|tongue skeletal muscle|skeletal muscle tissue of tongue|musculi linguae|muscle organ of tongue|tongue skeletal muscle tissue The muscular portion of the tongue. GO:2001080 chitosan binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_2001080 Interacting selectively and non-covalently with chitosan. UBERON:0000379 tracheal mucosa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000379 mucosa of windpipe|mucous membrane of windpipe|trachea mucosa|windpipe mucosa of organ|windpipe organ mucosa|mucous membrane of trachea|mucosa of trachea|tunica mucosa tracheae|tunica mucosa (tracheae)|windpipe mucous membrane|mucosa of organ of trachea|organ mucosa of windpipe|trachea organ mucosa|windpipe mucosa|organ mucosa of trachea|trachea mucosa of organ|tracheal mucous membrane|mucosa of organ of windpipe|trachea mucous membrane A mucosa that is part of a respiratory airway. GO:2001081 (1->4)-beta-D-galactan binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_2001081 (1,4)-beta-D-galactan binding Interacting selectively and non-covalently with (1->4)-beta-D-galactan. GO:2001082 inulin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_2001082 Interacting selectively and non-covalently with inulin. GO:2001083 alpha-D-glucan binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_2001083 Interacting selectively and non-covalently with alpha-D-glucan. GO:2001084 L-arabinofuranose binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_2001084 Interacting selectively and non-covalently with L-arabinofuranose. CHEBI:76971 Escherichia coli metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76971 UBERON:0000375 mandibular nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000375 mandibular nerve [Vc]|trigeminal nerve mandibular division|nervus mandibularis [vc]|nervus mandibularis [Vc; V3]|nervus mandibularis|trigeminal V nerve mandibular division|mandibular division [Vc]|n. mandibularis|mandibular nerve [V3]|mandibular division of fifth cranial nerve|third division of trigeminal nerve|inferior maxillary nerve|mandibular division of trigeminal nerve [Vc; V3]|third division of fifth cranial nerve|nervus mandibularis [v3]|ramus mandibularis (ramus V3)|mandibular division [V3] The motor and sensory nerve subdivision of the trigeminal nerve that transmits sensory information from the auricle, the external acoustic meatus, tympanic membrane, temporal region, the cheek, the skin overlying the mandible, the anterior portion of the tongue, the floor of the mouth, lower teeth and gingiva and transmits motor information from the muscles of mastication, the mylohyoid muscle and digastric muscle and the muscles tensor tympani and tensor veli palatini. GO:2001085 arabinogalactan binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_2001085 Interacting selectively and non-covalently with arabinogalactan. CHEBI:27933 beta-lactam antibiotic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27933 CHEBI:76988 xenoestrogen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76988 CHEBI:76989 phytoestrogen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76989 CHEBI:76986 2-hydroxyhexacosanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76986 UBERON:0000358 blastocyst biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000358 blastocystis|blastula The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm[GO]. CHEBI:27931 alpha-maltotriose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27931 GO:2001097 laminaritriose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001097 The directed movement of a laminaritrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:2001098 tetrasaccharide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001098 The directed movement of a tetrasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:86315 methyl sulfide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86315 GO:2001099 maltotetraose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001099 The directed movement of a maltotetraoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:62345 L-rhamnose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62345 CHEBI:86316 3beta-hydroxychola-5,22-dien-24-oyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86316 CHEBI:86317 2-methyl-3-oxopalmitoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86317 CHEBI:62346 L-rhamnopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62346 CHEBI:86319 25-hydroxyvitamin D2 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86319 UBERON:0000365 urothelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000365 epithelium transitionale|transitional epithelium|transitional epithelium|uroepithelium An epithelial tissue layer that lines much of the urinary tract, including the renal pelvis, the ureters, the bladder, and parts of the urethra. CHEBI:76980 2-hydroxybehenic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76980 GO:2001090 maltotriulose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001090 The directed movement of a maltotriuloseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:76981 3-[(1-carboxylatovinyl)oxy]benzoate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76981 GO:2001091 nigerotriose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001091 The directed movement of a nigerotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:2001092 arabinotriose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001092 The directed movement of an arabinotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:2001093 galactotriose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001093 The directed movement of a galactotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:27937 cob(II)yrinic acid a,c diamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27937 CHEBI:27938 beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27938 UBERON:0000362 renal medulla biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000362 renal medullae set|medulla renalis|renal medullae|medullary pyramids|renal pyramids set|renal pyramids|medulla of kidney|kidney medulla|pyramides renales|renal marrow the inner portion of the kidney consisting of the renal pyramids GO:2001094 xylotriose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001094 The directed movement of a xylotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:2001095 mannotriose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001095 The directed movement of a mannotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:76982 2,3-dioctanoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76982 GO:2001096 cellotriose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001096 The directed movement of a cellotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:27947 D-histidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27947 UBERON:0000348 ophthalmic nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000348 profundus nerve|first division of fifth cranial nerve|ophthalmic division of trigeminal nerve (V1)|opthalmic nerve|nervus ophthalmicus [va]|ramus opthalmicus profundus (ramus V1)|nervus ophthalmicus (Va)|cranial nerve V, branch V1|ophthalmic nerve [Va]|profundus|ophthalmic division [Va]|ciliary nerve|rostral branch of trigeminal nerve|ophthalmic division|ethmoidal nerve|trigeminal nerve ophthalmic division|ophthalmic division of fifth cranial nerve|first division of trigeminal nerve|ophthalmic division of trigeminal nerve (Va)|profundal nerve|nervus ophthalmicus [v1]|trigeminal V nerve ophthalmic division|nervus ophthalmicus (V1)|first branch of fifth cranial nerve|ophthalmic nerve [V1]|ophthalmic division [V1] The sensory nerve subdivision of the trigeminal nerve that transmits sensory information from the orbit and its contents, the nasal cavity and the skin of the nose and forehead. CHEBI:27941 pullulan biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27941 UBERON:0000349 limbic system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000349 visceral brain A set of midline structures surrounding the brainstem of the mammalian brain, originally described anatomically, e.g., hippocampal formation, amygdala, hypothalamus, cingulate cortex. Although the original designation was anatomical, the limbic system has come to be associated with the system in the brain subserving emotional functions. As such, it is very poorly defined and doesn't correspond closely to the anatomical meaning any longer. [BirnLex]. CHEBI:86301 20-methyl-3-oxopregna-4,17-dien-21-oyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86301 CHEBI:86305 3beta-hydroxychol-5-en-24-oyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86305 CHEBI:86308 17-hydroxy-3-oxopregn-4-en-20-carboxy-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86308 UBERON:0000355 pharyngeal mucosa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000355 organ mucosa of pharynx|pharynx mucosa of organ|mucous membrane of the pharynx|pharynx mucous membrane|tunica mucosa pharyngis|pharynx organ mucosa|mucous membrane of pharynx|mucosa of pharynx|tunica mucosa pharyngea|mucosa of organ of pharynx|pharynx mucosa A mucosa that is part of a pharynx [Automatically generated definition]. CHEBI:76992 2-hydroxyarachidic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76992 CHEBI:76990 mycoestrogen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76990 CHEBI:27948 dTDP-alpha-D-desosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27948 UBERON:0000351 nuchal ligament biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000351 paxwax|ligament of neck|paddywhack|ligamentum nuchae A fibrous membrane, which, in the neck, represents the supraspinal ligaments of the upper vertebrae. CHEBI:27949 (E)-sinapaldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27949 UBERON:0000353 parenchyma biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000353 functional part of an organ in the body. This is in contrast to the stroma, which refers to the structural tissue of organs, being exactly, connective tissues. CHEBI:144635 D-2,4-diaminobutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_144635 GO:0035427 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035427 GO:0035428 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035428 GO:0035429 gluconate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035429 gluconate membrane transport|gluconate transport The process in which gluconate is transported across a membrane. Gluconate is the aldonic acid derived from glucose. GO:0035420 MAPK cascade involved in innate immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035420 MAPKKK cascade involved in innate immune response A MAPK cascade that contributes to an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens. GO:0035421 obsolete activation of MAPKK activity involved in innate immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035421 OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens. GO:0035422 obsolete activation of MAPKKK activity involved in innate immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035422 OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens. GO:0035423 inactivation of MAPK activity involved in innate immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035423 Any process that terminates the activity of the active enzyme MAP kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens. GO:0035424 obsolete MAPK import into nucleus involved in innate immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035424 nuclear translocation of MAPK involved in innate immune response OBSOLETE. The directed movement of a MAP kinase to the nucleus in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens. GO:0035425 autocrine signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035425 autocrine signalling Signaling between cells of the same type. The signal produced by the signaling cell binds to a receptor on, and affects a cell of the same type. GO:0035426 extracellular matrix-cell signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035426 extracellular matrix-cell signalling|cell-extracellular matrix signalling Any process that mediates the transfer of information between the extracellular matrix and a cell. CHEBI:1921 4-oxocyclohexanecarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_1921 CHEBI:144637 4-hydroxy-D-proline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_144637 CHEBI:37395 mucopolysaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37395 CHEBI:37392 ribonic acid phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37392 CHEBI:37393 1-(3-sn-phosphatidyl)-sn-glycerol 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37393 CHEBI:37398 nucleotide-aldonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37398 CHEBI:37396 proteoglycan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37396 CHEBI:37397 chondroitin sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37397 GO:0035416 obsolete positive regulation of mitotic prometaphase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035416 positive regulation of mitotic prometaphase OBSOLETE. Any process that activates or increases the frequency, rate or extent of mitotic prometaphase, the stage following prophase in mitosis (in higher eukaryotes) during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region. GO:0035417 obsolete negative regulation of mitotic prometaphase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035417 negative regulation of mitotic prometaphase OBSOLETE. Any process that stops, prevents or reduces the rate or extent of mitotic prometaphase, the stage following prophase in mitosis (in higher eukaryotes) during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region. GO:0035418 protein localization to synapse biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035418 protein localisation to synapse Any process in which a protein is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. GO:0035419 obsolete activation of MAPK activity involved in innate immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035419 OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens. GO:0035410 dihydrotestosterone 17-beta-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035410 EC:1.1.1.51 Catalysis of the reaction: 5alpha-dihydrotestosterone + NAD+ = 5alpha-androstane-3,17-dione + NADH. GO:0035411 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035411 GO:0035412 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035412 GO:0035413 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035413 GO:0035414 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035414 GO:0035415 obsolete regulation of mitotic prometaphase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035415 regulation of mitotic prometaphase OBSOLETE. Any process that modulates the frequency, rate or extent of mitotic prometaphase, the stage following prophase in mitosis (in higher eukaryotes) during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region. GO:0035405 histone-threonine phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035405 histone threonine phosphorylation The modification of histones by addition of a phosphate group to a threonine residue. GO:0035406 histone-tyrosine phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035406 histone tyrosine phosphorylation The modification of histones by addition of a phosphate group to a tyrosine residue. GO:0035407 histone H3-T11 phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035407 The modification of histone H3 by the addition of an phosphate group to a threonine residue at position 11 of the histone. GO:0035408 histone H3-T6 phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035408 The modification of histone H3 by the addition of an phosphate group to a threonine residue at position 6 of the histone. GO:0035409 histone H3-Y41 phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035409 The modification of histone H3 by the addition of a phosphate group to a tyrosine residue at position 41 of the histone. GO:0035400 histone tyrosine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035400 histone-tyrosine kinase activity Catalysis of the transfer of a phosphate group to a tyrosine residue of a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. GO:0035401 histone kinase activity (H3-Y41 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035401 histone-tyrosine kinase activity (H3-Y41 specific)|histone tyrosine kinase activity (H3-Y41 specific) Catalysis of the transfer of a phosphate group to the tyrosine-41 residue of histone H3. GO:0035402 histone kinase activity (H3-T11 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035402 histone threonine kinase activity (H3-T11 specific)|histone-threonine kinase activity (H3-T11 specific) Catalysis of the transfer of a phosphate group to the threonine-11 residue of the N-terminal tail of histone H3. GO:0035403 histone kinase activity (H3-T6 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035403 histone-threonine kinase activity (H3-T6 specific)|histone threonine kinase activity (H3-T6 specific) Catalysis of the transfer of a phosphate group to the threonine-6 residue of the N-terminal tail of histone H3. GO:0035404 histone-serine phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035404 histone serine phosphorylation The modification of histones by addition of a phosphate group to a serine residue. CHEBI:37373 (S)-3-hydroxyisobutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37373 CHEBI:37371 (S)-3-hydroxydecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37371 CHEBI:37374 (S)-3-hydroxytetradecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37374 CHEBI:37390 azoxy compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37390 CHEBI:52996 alpha-D-glucosyl-(1->3)-D-mannopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52996 CHEBI:52997 D-glucopyranosyl-(1->3)-D-mannopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52997 CHEBI:13389 NAD biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_13389 CHEBI:52994 precursor Z biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52994 CHEBI:52984 trans-2-hexacosenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52984 CHEBI:52985 2-hexacosenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52985 CHEBI:52987 L-asparagine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52987 UBERON:0014930 perivascular space biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014930 perivascular spaces|Virchow-Robin space|VRS|perivascular region The space between a blood vessel and the pia mater. CHEBI:52980 N-hexacosanoylphytosphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52980 CHEBI:76900 (3R,11Z)-3-hydroxyoctadecenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76900 CHEBI:52977 3-oxohexacosanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52977 CHEBI:52979 N-tetracosanoylphytosphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52979 UBERON:2007013 preplacodal ectoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_2007013 Non neural ectoderm that surrounds the presumptive neural plate and gives rise to neurogenic placodes. CHEBI:52973 ergosteryl 3-beta-D-glucoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52973 CHEBI:76904 (2E,11Z)-octadecadienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76904 CHEBI:52974 tetracosanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52974 CHEBI:76905 (13Z)-3-oxoicosenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76905 CHEBI:52975 trans-2-hexacosenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52975 CHEBI:76902 EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76902 CHEBI:76908 (3R,13Z)-3-hydroxyicosenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76908 CHEBI:76909 (2E,13Z)-icosadienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76909 CHEBI:76906 EC 4.1.1.* (carboxy-lyase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76906 CHEBI:76907 EC 4.2.1.* (hydro-lyases) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76907 CHEBI:1949 4alpha-methylzymosterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_1949 CHEBI:37334 diagnostic imaging agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37334 CHEBI:37335 MRI contrast agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37335 CHEBI:1941 4-(trimethylammonio)butanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_1941 CHEBI:52970 ubiquinol-6 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52970 CHEBI:52971 ubiquinone-6 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52971 CHEBI:52972 ergosta-5,7,24(28)-trien-3beta-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52972 CHEBI:37332 tropane alkaloid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37332 CHEBI:37331 (E)-penta-2,4-dienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37331 CHEBI:52966 hexacosanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52966 CHEBI:76910 (13Z)-icosenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76910 CHEBI:52962 N-hexacosanoylsphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52962 CHEBI:76915 N,N-dimethyl-L-alaniniumyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76915 CHEBI:76913 L-cysteinate group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76913 CHEBI:1958 5'-dehydroadenosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_1958 UBERON:0014907 intersomitic vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014907 intersegmental vessel|intersomitic blood vessel|intersegmental vessels|segmental vessel|intersomitic vessels One of the primary blood vessel sprouts that originate from the dorsal aorta and posterior cardinal vein and align dorsoventrally at the myotomal boundaries between somites. UBERON:0014903 primordial vasculature biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014903 A portion of tissue that will develop into vasculature. CHEBI:52961 N-tetracosanoylsphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52961 CHEBI:13390 NAD(P)(+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_13390 CHEBI:13392 NAD(P)H biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_13392 GO:0098961 dendritic transport of ribonucleoprotein complex biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098961 dendritic transport of RNP complex The directed movement of a ribonucleoprotein complex along microtubules in nerve cell dendrites. GO:0098962 regulation of postsynaptic neurotransmitter receptor activity biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098962 Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity involved in synaptic transmission. Modulation may be via an effect on ligand affinity, or effector funtion such as ion selectivity or pore opening/closing in ionotropic receptors. GO:0098960 postsynaptic neurotransmitter receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098960 neurotransmitter receptor activity involved in chemical synaptic transmission Neurotransmitter receptor activity occuring in the postsynaptic membrane during synaptic transmission. GO:1902539 multi-organism macropinocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902539 A macropinocytosis which involves another organism. GO:1902537 obsolete multi-organism pinocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902537 OBSOLETE. A pinocytosis which involves another organism. CHEBI:86293 3,22-dioxochol-4-en-24-oyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86293 CHEBI:86294 N-acyl-(4E,8E,10E)-sphinga-4,8,10-trienine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86294 GO:1902538 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902538 GO:1902535 multi-organism membrane invagination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902535 A membrane invagination which involves another organism. GO:1902536 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902536 GO:1902533 positive regulation of intracellular signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902533 up-regulation of signal transmission via intracellular cascade|up regulation of intracellular signal transduction|activation of intracellular signal transduction|upregulation of intracellular signaling cascade|up-regulation of intracellular signaling pathway|upregulation of intracellular signal transduction pathway|up regulation of signal transduction via intracellular signaling cascade|upregulation of signal transmission via intracellular cascade|up-regulation of intracellular signaling chain|activation of intracellular signaling cascade|positive regulation of signal transduction via intracellular signaling cascade|positive regulation of intracellular protein kinase cascade|up regulation of intracellular signaling cascade|upregulation of intracellular signaling pathway|up-regulation of intracellular signal transduction|positive regulation of intracellular signaling cascade|activation of signal transduction via intracellular signaling cascade|up regulation of intracellular signal transduction pathway|upregulation of intracellular signaling chain|positive regulation of intracellular signal transduction pathway|up regulation of signal transmission via intracellular cascade|positive regulation of signal transmission via intracellular cascade|up-regulation of signal transduction via intracellular signaling cascade|up regulation of intracellular signaling pathway|upregulation of intracellular signal transduction|activation of intracellular signal transduction pathway|positive regulation of intracellular signaling pathway|up-regulation of intracellular signaling cascade|activation of signal transmission via intracellular cascade|up regulation of intracellular signaling chain|activation of intracellular signaling chain|activation of intracellular signaling pathway|positive regulation of intracellular signaling chain|up-regulation of intracellular signal transduction pathway|upregulation of signal transduction via intracellular signaling cascade Any process that activates or increases the frequency, rate or extent of intracellular signal transduction. GO:1902534 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902534 CHEBI:86298 O-[S-5-hexenoylpantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86298 GO:1902531 regulation of intracellular signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902531 regulation of intracellular signaling cascade|regulation of signal transduction via intracellular signaling cascade|regulation of intracellular signal transduction pathway|regulation of signal transmission via intracellular cascade|regulation of intracellular signaling pathway|regulation of intracellular protein kinase cascade|regulation of intracellular signaling chain Any process that modulates the frequency, rate or extent of intracellular signal transduction. CHEBI:86299 O-[S-5-hexynoylpantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86299 GO:1902532 negative regulation of intracellular signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902532 downregulation of intracellular signaling cascade|negative regulation of intracellular signaling chain|down-regulation of intracellular signaling chain|down regulation of signal transduction via intracellular signaling cascade|down-regulation of signal transmission via intracellular cascade|inhibition of intracellular signal transduction pathway|inhibition of signal transmission via intracellular cascade|downregulation of signal transduction via intracellular signaling cascade|down-regulation of intracellular signal transduction|inhibition of intracellular signaling chain|inhibition of intracellular signaling pathway|down regulation of intracellular signal transduction pathway|down regulation of signal transmission via intracellular cascade|inhibition of intracellular signal transduction|negative regulation of intracellular protein kinase cascade|negative regulation of intracellular signaling cascade|downregulation of intracellular signal transduction pathway|negative regulation of signal transduction via intracellular signaling cascade|down-regulation of signal transduction via intracellular signaling cascade|down regulation of intracellular signaling pathway|downregulation of signal transmission via intracellular cascade|down-regulation of intracellular signaling cascade|downregulation of intracellular signaling pathway|down regulation of intracellular signaling chain|inhibition of intracellular signaling cascade|negative regulation of intracellular signal transduction pathway|down-regulation of intracellular signal transduction pathway|downregulation of intracellular signaling chain|negative regulation of signal transmission via intracellular cascade|down regulation of intracellular signal transduction|inhibition of signal transduction via intracellular signaling cascade|down regulation of intracellular signaling cascade|negative regulation of intracellular signaling pathway|down-regulation of intracellular signaling pathway|downregulation of intracellular signal transduction Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction. GO:0060350 endochondral bone morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060350 The process in which bones are generated and organized as a result of the conversion of initial cartilaginous anlage into bone. GO:0060351 cartilage development involved in endochondral bone morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060351 The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones. GO:0060352 cell adhesion molecule production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060352 The appearance of a cell adhesion molecule due to biosynthesis or secretion. GO:1902530 positive regulation of protein linear polyubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902530 upregulation of protein linear polyubiquitination|upregulation of M1 linkage|up regulation of protein linear polyubiquitination|activation of protein linear polyubiquitination|up-regulation of M1 linkage|activation of M1 linkage|up-regulation of protein linear polyubiquitination|positive regulation of M1 linkage|up regulation of M1 linkage Any process that activates or increases the frequency, rate or extent of protein linear polyubiquitination. GO:0060353 regulation of cell adhesion molecule production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060353 Any process that modulates the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism. GO:0035386 regulation of Roundabout signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035386 regulation of Roundabout signalling pathway Any process that modulates the frequency, rate or extent of the Roundabout signaling pathway. GO:0060354 negative regulation of cell adhesion molecule production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060354 Any process that decreases the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism. GO:0035387 negative regulation of Roundabout signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035387 negative regulation of Roundabout signalling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the Roundabout signaling pathway. GO:0035388 positive regulation of Roundabout signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035388 positive regulation of Roundabout signalling pathway Any process that activates or increases the frequency, rate or extent of the Roundabout signaling pathway. GO:0060355 positive regulation of cell adhesion molecule production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060355 Any process that increases the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism. GO:0060356 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0060356 GO:0035389 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035389 GO:0060357 regulation of leucine import biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060357 regulation of L-leucine import|regulation of L-leucine uptake|regulation of leucine uptake Any process that modulates the rate, frequency or extent of leucine import. Leucine import is the directed movement of leucine into a cell or organelle. GO:0060358 negative regulation of leucine import biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060358 Any process that decreases the rate, frequency or extent of leucine import. Leucine import is the directed movement of leucine into a cell or organelle. GO:0060359 response to ammonium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060359 response to ammonia Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus. GO:0098969 neurotransmitter receptor transport to postsynaptic membrane biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098969 The directed movement of neurotransmitter receptor to the postsynaptic membrane in transport vesicles. GO:0035380 very long-chain-3-hydroxyacyl-CoA dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035380 very-long-chain-3-hydroxyacyl-CoA dehydrogenase activity Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD(P)+ = 3-oxoacyl-CoA + NAD(P)H + H+, where the acyl group is a very long-chain fatty acid residue. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22. GO:0098967 exocytic insertion of neurotransmitter receptor to postsynaptic membrane biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098967 The exocytic fusion of neurotransmitter receptor containing vesicles with the postsynaptic membrane resulting in the integration of NT receptors, enabling them to participate in neurotransmitter reception. This process includes tethering and docking steps that prepare vesicles for fusion. GO:0035381 ATP-gated ion channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035381 Enables the transmembrane transfer of an ion by a channel that opens when ATP has been bound by the channel complex or one of its constituent parts. GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098968 Vesicle-mediated transport of a neurotransmitter receptor complex from the postsynaptic membrane to the postsynaptic early endosome. GO:0035382 sterol transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035382 sterol membrane transport The process in which a sterol is transported across a membrane. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. GO:0098965 extracellular matrix of synaptic cleft biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098965 synaptic cleft ECM|ECM of synaptic cleft The portion of the extracellular matrix that lies within the synaptic cleft. GO:0098966 perisynaptic extracellular matrix biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098966 perisynaptic ECM|extrasynaptic extracellular matrix The portion of the extracellular matrix that lies within the perisynaptic space. GO:0035383 thioester metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035383 thioester metabolism The chemical reactions and pathways involving a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol. GO:0098963 dendritic transport of messenger ribonucleoprotein complex biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098963 dendritic transport of mRNA RNP complex The directed movement of a messenger ribonucleoprotein complex along microtubules in nerve cell dendrites. GO:0035384 thioester biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035384 thioester biosynthesis|thioester anabolism|thioester synthesis|thioester formation The chemical reactions and pathways resulting in the formation of a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol. GO:0098964 anterograde dendritic transport of messenger ribonucleoprotein complex biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098964 anterograde dendritic transport of mRNA RNP complex The directed movement of a messenger ribonucleoprotein complex along microtubules in nerve cell dendrites towards the postsynapse. GO:0035385 Roundabout signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035385 ROBO signaling pathway|ROBO/SLIT signaling pathway|Roundabout signalling pathway A series of molecular signals initiated by the binding of a SLIT protein to a Roundabout (ROBO) family receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0098972 anterograde dendritic transport of mitochondrion biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098972 The directed movement of mitochondria along microtubules in dendrites towards the postsynapse and away from the cell body. GO:0098973 structural constituent of postsynaptic actin cytoskeleton biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098973 The action of a molecule that contributes to the structural integrity of a postsynaptic actin cytoskeleton. GO:0098970 postsynaptic neurotransmitter receptor diffusion trapping biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098970 The process by which diffusing neurotransmitter receptor becomes trapped at the postsynaptic specialization membrane. This is typically due to interaction with components of the post-synaptic specialization. GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098971 The directed movement of a neurotransmitter receptor complex along microtubules in nerve cell dendrites towards the postsynapse. GO:1902548 negative regulation of cellular response to vascular endothelial growth factor stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902548 downregulation of cellular response to vascular endothelial growth factor|downregulation of cellular response to VEGF|downregulation of cellular response to VEGFB|downregulation of cellular response to VEGFA|negative regulation of cellular response to vascular endothelial growth factor|down-regulation of cellular response to vascular endothelial growth factor|down regulation of cellular response to VEGFB|down regulation of cellular response to VEGFA|down-regulation of cellular response to VEGF|down-regulation of cellular response to vascular endothelial growth factor stimulus|negative regulation of cellular response to VEGF|inhibition of cellular response to VEGFB|inhibition of cellular response to vascular endothelial growth factor|inhibition of cellular response to VEGFA|inhibition of cellular response to VEGF|downregulation of cellular response to vascular endothelial growth factor stimulus|down regulation of cellular response to vascular endothelial growth factor stimulus|inhibition of cellular response to vascular endothelial growth factor stimulus|down regulation of cellular response to vascular endothelial growth factor|down-regulation of cellular response to VEGFB|negative regulation of cellular response to VEGFB|down-regulation of cellular response to VEGFA|negative regulation of cellular response to VEGFA|down regulation of cellular response to VEGF Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to vascular endothelial growth factor stimulus. GO:1902549 protein localization to Mei2 nuclear dot biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902549 protein localization to Mei2 dot|protein localisation to Mei2 nuclear dot|protein localisation in Mei2 nuclear dot|protein localization in Mei2 nuclear dot A process in which a protein is transported to, or maintained in, a location within a Mei2 nuclear dot. CHEBI:86284 CMP-3-deoxy-beta-D-manno-octulosonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86284 GO:1902546 positive regulation of DNA N-glycosylase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902546 up-regulation of DNA glycosylase activity|up-regulation of DNA N-glycosylase activity|activation of DNA glycosylase activity|up-regulation of endonuclease VIII activity|activation of DNA N-glycosylase activity|activation of endonuclease VIII activity|positive regulation of DNA glycosylase activity|up regulation of DNA glycosylase activity|positive regulation of endonuclease VIII activity|up regulation of DNA N-glycosylase activity|up regulation of endonuclease VIII activity|upregulation of DNA glycosylase activity|upregulation of DNA N-glycosylase activity|upregulation of endonuclease VIII activity Any process that activates or increases the frequency, rate or extent of DNA N-glycosylase activity. GO:1902547 regulation of cellular response to vascular endothelial growth factor stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902547 regulation of cellular response to VEGFB|regulation of cellular response to VEGFA|regulation of cellular response to vascular endothelial growth factor|regulation of cellular response to VEGF Any process that modulates the frequency, rate or extent of cellular response to vascular endothelial growth factor stimulus. GO:1902544 regulation of DNA N-glycosylase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902544 regulation of DNA glycosylase activity|regulation of endonuclease VIII activity Any process that modulates the frequency, rate or extent of DNA N-glycosylase activity. CHEBI:86287 GDP-N,N'-diacetylbacillosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86287 GO:1902545 negative regulation of DNA N-glycosylase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902545 inhibition of endonuclease VIII activity|down-regulation of DNA glycosylase activity|negative regulation of DNA glycosylase activity|negative regulation of endonuclease VIII activity|down-regulation of endonuclease VIII activity|down-regulation of DNA N-glycosylase activity|downregulation of DNA glycosylase activity|downregulation of DNA N-glycosylase activity|downregulation of endonuclease VIII activity|down regulation of DNA glycosylase activity|down regulation of endonuclease VIII activity|down regulation of DNA N-glycosylase activity|inhibition of DNA glycosylase activity|inhibition of DNA N-glycosylase activity Any process that stops, prevents or reduces the frequency, rate or extent of DNA N-glycosylase activity. GO:1902542 regulation of protein localization to mitotic spindle pole body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902542 regulation of protein localisation to mitotic spindle pole body Any process that modulates the frequency, rate or extent of protein localization to mitotic spindle pole body. GO:1902543 negative regulation of protein localization to mitotic spindle pole body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902543 down regulation of protein localization to mitotic spindle pole body|downregulation of protein localization to mitotic spindle pole body|down regulation of protein localisation to mitotic spindle pole body|down-regulation of protein localisation in mitotic spindle pole body|downregulation of protein localisation to mitotic spindle pole body|down-regulation of protein localization to mitotic spindle pole body|inhibition of protein localization to mitotic spindle pole body|down-regulation of protein localisation to mitotic spindle pole body|negative regulation of protein localisation to mitotic spindle pole body|inhibition of protein localisation to mitotic spindle pole body Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to mitotic spindle pole body. GO:0060340 positive regulation of type I interferon-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060340 positive regulation of type I interferon-mediated signalling pathway Any process that increases the rate, frequency or extent of a type I interferon-mediated signaling pathway. A type I interferon-mediated signaling pathway is the series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor. GO:1902540 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902540 GO:1902541 multi-organism micropinocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902541 A micropinocytosis which involves another organism. GO:0060341 regulation of cellular localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060341 regulation of cellular localisation Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell. GO:0060342 photoreceptor inner segment membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0060342 The membrane surrounding the inner segment of a vertebrate photoreceptor. The photoreceptor inner segment contains mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs. GO:0035375 zymogen binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035375 proenzyme binding Interacting selectively and non-covalently with a zymogen, an enzymatically inactive precursor of an enzyme that is often convertible to an active enzyme by proteolysis. GO:0060343 trabecula formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060343 trabecula biogenesis|trabeculation The process of creating a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue. GO:1902550 lymphoid lineage cell migration into thymus involved in thymus epithelium morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902550 lymphoid lineage cell migration into thymus involved in thymic epithelium morphogenesis|lymphoid lineage restricted progenitor cell migration into thymus involved in thymic epithelium morphogenesis|lymphoid lineage restricted progenitor cell migration into thymus involved in thymus epithelium morphogenesis Any lymphoid lineage cell migration into thymus that is involved in thymus epithelium morphogenesis. GO:0035376 sterol import biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035376 sterol uptake|sterol influx The directed movement of a sterol into a cell or organelle. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. GO:0060344 liver trabecula formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060344 liver trabeculation|liver trabecula biogenesis The process of creating a trabecula in the liver. A trabecula is a tissue element in the form of a small beam, strut or rod. GO:0035377 transepithelial water transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035377 The directed movement of water (H2O) from one side of an epithelium to the other. GO:0060345 spleen trabecula formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060345 spleen trabecula biogenesis|spleen trabeculation The process of creating a trabecula in the spleen. A trabecula is a tissue element in the form of a small beam, strut or rod. GO:0035378 carbon dioxide transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035378 carbon dioxide membrane transport The process in which carbon dioxide (CO2) is transported across a membrane. GO:0035379 carbon dioxide transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035379 Reactome:R-HSA-1247649|Reactome:R-HSA-1237069|Reactome:R-HSA-1247645|Reactome:R-HSA-1237042 Enables the transfer of carbon dioxide (CO2) from one side of a membrane to the other. GO:0060346 bone trabecula formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060346 bone trabecula biogenesis|bone trabeculation|skeletal trabeculation|skeletal trabecula formation|skeletal trabecula biogenesis The process of creating a trabecula in the bone. A trabecula is a tissue element in the form of a small beam, strut or rod. GO:0060347 heart trabecula formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060347 heart trabecula biogenesis|heart trabeculation|cardiac trabeculation|cardiac trabecula formation The process of creating a trabecula in the heart. A trabecula is a tissue element in the form of a small beam, strut or rod. GO:0060348 bone development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060348 The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components. CHEBI:129091 (9Z,12R)-12,18-dihydroxyoctadecenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_129091 GO:0060349 bone morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060349 The process in which bones are generated and organized. GO:0098978 glutamatergic synapse biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098978 A synapse that uses glutamate as a neurotransmitter. GO:0035370 UBC13-UEV1A complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035370 A heterodimeric ubiquitin conjugating enzyme complex that catalyzes assembly of K63-linked polyubiquitin chains and is involved in NF-kappaB activation. In humans at least, the complex comprises the ubiquitin-conjugating enzyme UBC13 and ubiquitin-conjugating enzyme variant 1A (UEV1A). GO:0098979 polyadic synapse biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098979 A synapse consisting of a single presynapse and multiple postsynapses. These postsynapses may come from the same cell of from different cells. Polyadic synapses are common in arthropod and nematode central nervous systems. GO:0035371 microtubule plus-end biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035371 microtubule plus end|growing microtubule plus end The growing (plus) end of a microtubule. In vitro, microtubules polymerize more quickly at the plus end than at the minus end. In vivo, microtubule growth occurs only at the plus end, and the plus end switches between periods of growth and shortening, a behavior known as dynamic instability. GO:0098976 excitatory chemical synaptic transmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098976 Synaptic transmission that results in an excitatory postsynaptic potential. GO:0098977 inhibitory chemical synaptic transmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098977 Synaptic transmission that results in an inhibitory postsynaptic potential. GO:0035372 protein localization to microtubule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035372 protein localisation to microtubule A process in which a protein is transported to, or maintained at, a microtubule. GO:0098974 postsynaptic actin cytoskeleton organization biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098974 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the postsynaptic actin cytoskeleton. GO:0035373 chondroitin sulfate proteoglycan binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035373 Interacting selectively and non-covalently with a chondroitin sulfate proteoglycan, any proteoglycan containing chondroitin sulfate as the glycosaminoglycan carbohydrate unit. CHEBI:130073 5,20-diHEPE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_130073 GO:0035374 chondroitin sulfate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035374 Interacting selectively and non-covalently with chondroitin sulfate, a glycosaminoglycan made up of two alternating monosaccharides: D-glucuronic acid (GlcA) and N-acetyl-D-galactosamine (GalNAc). GO:0098975 postsynapse of neuromuscular junction biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098975 The postsynapse of a neuromuscular junction. In vertebrate muscles this includes the motor end-plate, consisting of postjunctional folds of the sarcolemma. GO:0098940 anterograde trans-synaptic signaling by nitric oxide biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098940 Cell-cell signaling from presynapse to postynapse, across the synaptic cleft, mediated by nitric oxide. GO:1902559 3'-phospho-5'-adenylyl sulfate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902559 3'-phosphoadenosine 5'-phosphosulfate transmembrane transport The process in which 3'-phospho-5'-adenylyl sulfate is transported across a membrane. GO:1902557 5'-adenylyl sulfate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1902557 Enables the transfer of 5'-adenylyl sulfate from one side of a membrane to the other. CHEBI:1989 (6R)-5,10-methylenetetrahydrofolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_1989 GO:1902558 5'-adenylyl sulfate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902558 adenosine 5'-phosphosulfate transmembrane transport The process in which 5'-adenylyl sulfate is transported across a membrane. GO:1902555 endoribonuclease complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902555 Ire1 complex homodimer|Ire1 complex homooligomer|Ire1 complex dimer A protein complex which is capable of endoribonuclease activity. GO:1902556 phosphatidylinositol transporter complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902556 Ire1 complex dimer|Ire1 complex homodimer|Ire1 complex homooligomer A protein complex which is capable of phosphatidylinositol transporter activity. GO:0060370 susceptibility to T cell mediated cytotoxicity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060370 The process of causing a cell to become susceptible to T cell mediated cytotoxicity. GO:1902553 positive regulation of catalase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902553 upregulation of CAT|activation of haem catalase activity|up-regulation of equilase activity|up regulation of caperase activity|activation of caperase activity|activation of manganese catalase activity|positive regulation of caperase activity|up-regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|upregulation of bacterial catalase-peroxidase activity|up regulation of catalase reaction|activation of catalase reaction|positive regulation of haem catalase activity|up-regulation of heme catalase activity|positive regulation of catalase reaction|upregulation of optidase activity|positive regulation of catalase-peroxidase activity|up regulation of haem catalase activity|up-regulation of manganese catalase activity|upregulation of equilase activity|up regulation of catalase-peroxidase activity|up regulation of CAT|up-regulation of catalase activity|activation of heme catalase activity|positive regulation of CAT|up-regulation of caperase activity|up-regulation of bacterial catalase-peroxidase activity|upregulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|positive regulation of heme catalase activity|up-regulation of catalase reaction|upregulation of haem catalase activity|activation of CAT|up regulation of optidase activity|upregulation of manganese catalase activity|activation of optidase activity|up regulation of heme catalase activity|positive regulation of optidase activity|up regulation of equilase activity|activation of bacterial catalase-peroxidase activity|upregulation of catalase-peroxidase activity|activation of equilase activity|upregulation of catalase activity|positive regulation of equilase activity|upregulation of caperase activity|up-regulation of CAT|up regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|activation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|positive regulation of bacterial catalase-peroxidase activity|positive regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|up-regulation of haem catalase activity|up regulation of bacterial catalase-peroxidase activity|upregulation of catalase reaction|up regulation of manganese catalase activity|activation of catalase-peroxidase activity|up-regulation of catalase-peroxidase activity|positive regulation of manganese catalase activity|upregulation of heme catalase activity|up-regulation of optidase activity|up regulation of catalase activity|activation of catalase activity Any process that activates or increases the frequency, rate or extent of catalase activity. GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060371 electrocardiogram PR interval|regulation of atrial cardiac muscle cell depolarization|atrial depolarization|regulation of atrial cardiomyocyte membrane depolarization Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in an atrial cardiomyocyte. GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060372 atrial repolarization|regulation of atrial cardiomyocyte membrane repolarization|electrocardiogram QRS complex|regulation of atrial cardiac muscle cell repolarization Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential in an atrial cardiomyocyte. GO:1902554 serine/threonine protein kinase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902554 PDR16 complex dimer|PDR16 complex homodimer A protein complex which is capable of protein serine/threonine kinase activity. GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060373 ventricular depolarization|electrocardiogram QRS complex|regulation of ventricular cardiomyocyte membrane depolarization Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in a ventricular cardiomyocyte. GO:1902551 regulation of catalase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902551 regulation of CAT|regulation of optidase activity|regulation of haem catalase activity|regulation of equilase activity|regulation of catalase-peroxidase activity|regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|regulation of manganese catalase activity|regulation of heme catalase activity|regulation of caperase activity|regulation of bacterial catalase-peroxidase activity|regulation of catalase reaction Any process that modulates the frequency, rate or extent of catalase activity. GO:0060374 mast cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060374 The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. GO:1902552 negative regulation of catalase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902552 downregulation of catalase reaction|down-regulation of haem catalase activity|negative regulation of haem catalase activity|down-regulation of manganese catalase activity|inhibition of heme catalase activity|negative regulation of manganese catalase activity|down regulation of bacterial catalase-peroxidase activity|down regulation of CAT|down-regulation of catalase-peroxidase activity|negative regulation of catalase-peroxidase activity|inhibition of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|down-regulation of catalase activity|down-regulation of caperase activity|negative regulation of caperase activity|downregulation of CAT|inhibition of bacterial catalase-peroxidase activity|down regulation of optidase activity|down-regulation of catalase reaction|negative regulation of catalase reaction|inhibition of catalase activity|downregulation of haem catalase activity|downregulation of catalase-peroxidase activity|down regulation of equilase activity|inhibition of caperase activity|down-regulation of heme catalase activity|downregulation of optidase activity|negative regulation of heme catalase activity|inhibition of manganese catalase activity|down regulation of haem catalase activity|down regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|downregulation of equilase activity|down regulation of catalase-peroxidase activity|down-regulation of CAT|negative regulation of CAT|inhibition of catalase reaction|inhibition of catalase-peroxidase activity|downregulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|down regulation of manganese catalase activity|negative regulation of bacterial catalase-peroxidase activity|down-regulation of bacterial catalase-peroxidase activity|inhibition of haem catalase activity|down regulation of catalase activity|negative regulation of optidase activity|down-regulation of optidase activity|downregulation of heme catalase activity|down regulation of caperase activity|down-regulation of equilase activity|negative regulation of equilase activity|downregulation of manganese catalase activity|down regulation of heme catalase activity|downregulation of catalase activity|inhibition of CAT|down regulation of catalase reaction|downregulation of caperase activity|negative regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|down-regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|downregulation of bacterial catalase-peroxidase activity|inhibition of optidase activity|inhibition of equilase activity Any process that stops, prevents or reduces the frequency, rate or extent of catalase activity. GO:0035364 thymine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035364 thymine transmembrane transport|5-methyluracil transport The directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0060375 regulation of mast cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060375 Any process that modulates the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. GO:1902560 GMP reductase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902560 guanosine monophosphate reductase|GMPR2 complex|GMPR1 complex|GMP reductase An oxidoreductase complex which is capable of GMP reductase activity. It catalyses the irreversible reaction: GMP + 2 H(+) + NADPH => IMP + NADP(+) + NH(4)(+). GO:0060376 positive regulation of mast cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060376 Any process that increases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. GO:0035365 regulation of thymine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035365 regulation of 5-methyluracil transport Any process that modulates the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:1902561 origin recognition complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902561 ORC assembly|origin of replication recognition complex assembly|origin recognition complex formation|origin of replication recognition complex formation|ORC formation The aggregation, arrangement and bonding together of a set of components to form an origin recognition complex. GO:0060377 negative regulation of mast cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060377 Any process that decreases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. GO:0035366 negative regulation of thymine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035366 negative regulation of 5-methyluracil transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0060378 regulation of brood size biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060378 Any process that modulates brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time. GO:0035367 positive regulation of thymine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035367 positive regulation of 5-methyluracil transport Any process that activates or increases the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0060379 cardiac muscle cell myoblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060379 cardiac myoblast differentiation|myocardial precursor cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a cardiac myoblast. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life. GO:0035368 selenocysteine insertion sequence binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035368 SECIS binding Interacting selectively and non-covalently with the selenocysteine insertion sequence (SECIS), a regulatory sequence within mRNA which directs incorporation of a selenocysteine at a stop codon (UGA) during translation. GO:0035369 pre-B cell receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035369 pre-BCR An immunoglobulin-like complex that is present in at least the plasma membrane of pre-B cells, and that is composed of two identical immunoglobulin heavy chains and two surrogate light chains, each composed of the lambda-5 and VpreB proteins, and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins. GO:0098949 intrinsic component of postsynaptic endosome membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098949 intrinsic to postsynaptic endosome membrane The component of the postsynaptic endosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0098947 intrinsic component of postsynaptic endocytic zone membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098947 intrinsic to postsynaptic acive zone membrane The component of the postsynaptic endocytic zone membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0098948 intrinsic component of postsynaptic specialization membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098948 intrinsic to postsynaptic specialization membrane The component of the postsynaptic specialization membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0098945 intrinsic component of presynaptic active zone membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098945 intrinsic to presynaptic acive zone membrane The component of the presynaptic active zone membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0098946 intrinsic component of presynaptic endocytic zone membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098946 intrinsic to presynaptic acive zone membrane The component of the presynaptic endocytic zone membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035360 positive regulation of PPAR signaling pathway|positive regulation of peroxisome proliferator-activated receptor signaling pathway|positive regulation of peroxisome proliferator activated receptor signalling pathway Any process that activates or increases the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway. GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098943 postsynaptic neurotransmitter receptor endosomal trafficking The directed movement of neurotransmitter receptor from the postsynaptic endosome in tranpsort vesicles to the lysosome for degradation. GO:0035361 Cul8-RING ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035361 A ubiquitin ligase complex in which a cullin from the Cul8 subfamily and a RING domain protein form the catalytic core. In S. cerevisiae, Mms1p acts as the adaptor protein and substrate specificity is conferred by any of a number of different proteins. GO:0098944 postsynaptic recycling endosome membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098944 The lipid bilayer surrounding a postsynaptic recycling endosome. GO:0098941 anterograde trans-synaptic signaling by trans-synaptic protein complex biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098941 Cell-cell signaling from presynapse to postynapse, across the synaptic cleft, mediated by a trans-synaptic protein complex. GO:0035362 protein-DNA ISRE complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035362 protein-DNA interferon-stimulated response element complex assembly The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex, in which the complex is formed through interaction of the protein(s) with a interferon-stimulated response element (ISRE) in the DNA. GO:0098942 retrograde trans-synaptic signaling by trans-synaptic protein complex biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098942 Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by trans-synaptic protein complex. GO:0035363 histone locus body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035363 HLB A nuclear body associated with the histone gene locus that is thought to contain all of the factors necessary for histone mRNA transcription and pre-mRNA processing. In Drosophila, U7 snRNP is located in the histone locus body rather than the distinct Cajal body. GO:0098950 intrinsic component of postsynaptic early endosome membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098950 intrinsic to postsynaptic early endosome membrane The component of the postsynaptic early endosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0098951 intrinsic component of postsynaptic recycling endosome membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098951 intrinsic to postsynaptic recycling endosome membrane The component of the postsynaptic recycling endosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:2001105 maltoheptaose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001105 The directed movement of a maltoheptaoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:1902568 positive regulation of eosinophil activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902568 upregulation of eosinophil activation|up regulation of eosinophil activation|activation of eosinophil activation|up-regulation of eosinophil activation Any process that activates or increases the frequency, rate or extent of eosinophil activation. GO:1902569 negative regulation of activation of Janus kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902569 down-regulation of activation of JAK1 protein|negative regulation of activation of JAK1 protein|downregulation of activation of JAK1 kinase activity|down regulation of tyrosine phosphorylation of JAK2 protein|inhibition of activation of JAK2 protein|down regulation of activation of JAK1 kinase activity|downregulation of tyrosine phosphorylation of JAK1 protein|down-regulation of activation of JAK2 kinase activity|inhibition of tyrosine phosphorylation of JAK2 protein|downregulation of activation of JAK1 protein|down regulation of tyrosine phosphorylation of JAK1 protein|down-regulation of tyrosine phosphorylation of JAK2 protein|inhibition of activation of JAK1 kinase activity|down regulation of activation of JAK1 protein|downregulation of activation of JAK2 kinase activity|negative regulation of activation of JAK2 protein|down-regulation of activation of JAK2 protein|inhibition of tyrosine phosphorylation of JAK1 protein|down regulation of activation of JAK2 kinase activity|inhibition of activation of JAK1 protein|negative regulation of tyrosine phosphorylation of JAK2 protein|negative regulation of activation of JAK2 kinase activity|down-regulation of activation of JAK1 kinase activity|inhibition of activation of JAK2 kinase activity|down regulation of activation of JAK2 protein|negative regulation of tyrosine phosphorylation of JAK1 protein|down-regulation of tyrosine phosphorylation of JAK1 protein|downregulation of tyrosine phosphorylation of JAK2 protein Any process that stops, prevents or reduces the frequency, rate or extent of activation of JAK (Janus Activated Kinase) kinase activity. GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001106 regulation of Rho guanine nucleotide exchange factor|regulation of RhoGEF Any process that modulates the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity. GO:1902566 regulation of eosinophil activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902566 Any process that modulates the frequency, rate or extent of eosinophil activation. GO:2001107 negative regulation of Rho guanyl-nucleotide exchange factor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001107 negative regulation of RhoGEF|negative regulation of Rho guanine nucleotide exchange factor Any process that stops, prevents or reduces the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity. GO:1902567 negative regulation of eosinophil activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902567 down regulation of eosinophil activation|downregulation of eosinophil activation|down-regulation of eosinophil activation|inhibition of eosinophil activation Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil activation. GO:2001108 positive regulation of Rho guanyl-nucleotide exchange factor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001108 positive regulation of RhoGEF|positive regulation of Rho guanine nucleotide exchange factor Any process that activates or increases the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity. GO:1902564 negative regulation of neutrophil activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902564 down-regulation of neutrophil activation|inhibition of neutrophil activation|down regulation of neutrophil activation|downregulation of neutrophil activation Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil activation. GO:2001109 regulation of lens epithelial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001109 Any process that modulates the frequency, rate or extent of lens epithelial cell proliferation. GO:0060360 negative regulation of leucine import in response to ammonium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060360 negative regulation of leucine uptake in response to ammonium ion Any process that decreases the rate, frequency or extent of leucine import as a result of an ammonium ion stimulus. Leucine import is the directed movement of leucine into a cell or organelle. GO:1902565 positive regulation of neutrophil activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902565 up regulation of neutrophil activation|activation of neutrophil activation|up-regulation of neutrophil activation|upregulation of neutrophil activation Any process that activates or increases the frequency, rate or extent of neutrophil activation. GO:0060361 flight biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060361 Self-propelled movement of an organism from one location to another through the air, usually by means of active wing movement. GO:1902562 H4 histone acetyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902562 Hpa3 (homo-)dimer|Hpa3 complex A protein complex which is capable of H4 histone acetyltransferase activity. GO:0060362 flight involved in flight behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060362 Self-propelled movement of an organism from one location to another through the air that is part of the organism's response to external or internal stimuli resulting in flight. GO:0060363 cranial suture morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060363 The process in which any suture between cranial bones is generated and organized. GO:1902563 regulation of neutrophil activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902563 Any process that modulates the frequency, rate or extent of neutrophil activation. GO:1902571 regulation of serine-type peptidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902571 regulation of serine protease activity Any process that modulates the frequency, rate or extent of serine-type peptidase activity. GO:0060364 frontal suture morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060364 interfrontal suture morphogenesis The process in which the frontal suture is generated and organized. GO:0035353 nicotinamide mononucleotide transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035353 nicotinamide mononucleotide membrane transport The process in which nicotinamide mononucleotide is transported across a membrane. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of d-ribose. It is a constituent of NAD and NADP. GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035354 TLR1:TLR2 complex|TLR1-TLR2 protein complex|TLR2:TLR1 heterodimer|toll-like receptor TLR1:TLR2 heterodimeric complex A heterodimeric protein complex containing Toll-like receptor 1 (TLR1) and Toll-like receptor 2 (TLR2). GO:1902572 negative regulation of serine-type peptidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902572 downregulation of serine-type peptidase activity|down-regulation of serine protease activity|negative regulation of serine protease activity|down regulation of serine-type peptidase activity|inhibition of serine-type peptidase activity|downregulation of serine protease activity|down regulation of serine protease activity|inhibition of serine protease activity|down-regulation of serine-type peptidase activity Any process that stops, prevents or reduces the frequency, rate or extent of serine-type peptidase activity. GO:0060365 coronal suture morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060365 The process in which the coronal suture is generated and organized. GO:0035355 Toll-like receptor 2-Toll-like receptor 6 protein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035355 toll-like receptor TLR6:TLR2 heterodimeric complex|TLR6:TLR2 complex|TLR2-TLR6 protein complex|TLR2:TLR6 heterodimer A heterodimeric protein complex containing Toll-like receptor 2 (TLR2) and Toll-like receptor 6 (TLR6). GO:0060366 lambdoid suture morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060366 The process in which the lambdoid suture is generated and organized. GO:0035356 cellular triglyceride homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035356 Any process involved in the maintenance of an internal steady state of triglyceride within a cell or between a cell and its external environment. GO:2001100 pentasaccharide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001100 The directed movement of a pentasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:1902570 protein localization to nucleolus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902570 protein localisation in nucleolus|protein localisation to nucleolus|protein localization in nucleolus A process in which a protein is transported to, or maintained in, a location within a nucleolus. GO:0060367 sagittal suture morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060367 The process in which the sagittal suture is generated and organized. GO:2001101 maltopentaose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001101 The directed movement of a maltopentaoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0035357 peroxisome proliferator activated receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035357 peroxisome proliferator activated receptor signalling pathway|PPAR signaling pathway|peroxisome proliferator-activated receptor signaling pathway The series of molecular signals initiated by binding of a ligand to any of the peroxisome proliferator activated receptors (alpha, beta or gamma) in the nuclear membrane, and ending with the initiation or termination of the transcription of target genes. GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060368 regulation of Fc receptor mediated stimulatory signalling pathway Any process that modulates the rate, frequency or extent of the Fc receptor mediated stimulatory signaling pathway. The Fc receptor mediated stimulatory signaling pathway is a series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of activating or perpetuating an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region. GO:0035358 regulation of peroxisome proliferator activated receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035358 regulation of peroxisome proliferator activated receptor signalling pathway|regulation of PPAR signaling pathway|regulation of peroxisome proliferator-activated receptor signaling pathway Any process that modulates the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway. GO:2001102 hexasaccharide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001102 The directed movement of a hexasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060369 positive regulation of Fc receptor mediated stimulatory signalling pathway Any process that increases the rate, frequency or extent of the Fc receptor mediated stimulatory signaling pathway. The Fc receptor mediated stimulatory signaling pathway is a series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of activating or perpetuating an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region. GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035359 negative regulation of peroxisome proliferator activated receptor signalling pathway|negative regulation of PPAR signaling pathway|negative regulation of peroxisome proliferator-activated receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway. GO:2001103 maltohexaose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001103 The directed movement of a maltohexaoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:2001104 heptasaccharide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001104 The directed movement of a heptasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0098958 retrograde axonal transport of mitochondrion biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098958 retrograde axon transport of mitochondria The directed movement of mitochondria along microtubules in axons towards the cell body and away from the presynapse. GO:0098959 retrograde dendritic transport of mitochondrion biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098959 retrograde dendrite transport of mitochondria The directed movement of mitochondria along microtubules in dendrites towards the cell body and away from the postsynapse. GO:0098956 intrinsic component of dense core granule membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098956 intrinsic to dense core granule membrane The component of the dense core granule membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0098957 anterograde axonal transport of mitochondrion biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098957 anterograde axon transport of mitochondria The directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse. GO:0098954 presynaptic endosome membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098954 The lipid bilayer surrounding a presynaptic endosome. GO:0098955 intrinsic component of presynaptic endosome membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098955 intrinsic to presynaptic endosome membrane The component of the presynaptic endosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0035350 FAD transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035350 FAD membrane transport The process in which flavin-adenine dinucleotide (FAD) is transported across a membrane. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form. GO:0035351 heme transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035351 heme membrane transport The process in which heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. GO:0098952 intrinsic component of spine apparatus membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098952 intrinsic to spine apparatus membrane The component of the spine apparatus membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0035352 NAD transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035352 NAD membrane transport The process in which a nicotinamide adenine dinucleotide is transported across a membrane; transport may be of either the oxidized form, NAD, or the reduced form, NADH. GO:0098953 receptor diffusion trapping biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098953 The process by which a membrane receptor, diffusing freely within the plasma membeane, becomes trapped in some plasma membrane region. This can happen when a receptor bind, directly or indirectly, to some component of the underlying matrix. GO:1902579 multi-organism localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902579 multi organism localization A localization which involves another organism. GO:0060390 regulation of SMAD protein signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060390 regulation of SMAD protein nuclear translocation|SMAD protein import into nucleus Any process that modulates the rate, frequency or extent of SMAD protein signal transduction. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways. GO:1902577 protein localization to medial cortical node biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902577 protein localisation to medial cortical node|protein localisation in medial cortical node|protein localization in medial cortical node A process in which a protein is transported to, or maintained in, a location within a medial cortical node. GO:0060391 positive regulation of SMAD protein signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060391 positive regulation of SMAD protein nuclear translocation|positive regulation of SMAD protein import into nucleus Any process that increases the rate, frequency or extent of SMAD protein signal transduction. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways. GO:0060392 negative regulation of SMAD protein signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060392 negative regulation of SMAD protein nuclear translocation|negative regulation of SMAD protein import into nucleus Any process that decreases the rate, frequency or extent of the SMAD protein signaling pathway. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways. GO:1902578 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902578 GO:1902575 protein localization to cell division site involved in cytokinesis, actomyosin contractile ring assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902575 protein localisation to cell division site involved in cytokinesis, actomyosin contractile ring assembly|protein localisation to cell division site involved in constriction ring assembly|protein localization to cell division site involved in contractile ring assembly|protein localization to cell division site involved in cytokinesis, actomyosin contractile ring formation|protein localisation to cell division site involved in cytokinesis, contractile ring assembly|protein localisation to cell division site involved in cytokinesis, actomyosin contractile ring formation|protein localisation to cell division site involved in cytokinesis, actomyosin ring biosynthesis|protein localization to cell division site involved in cytokinesis, actomyosin ring formation|protein localization to cell division site involved in cytokinesis, actomyosin ring biosynthesis|protein localization to cell division site involved in constriction ring assembly|protein localisation to cell division site involved in cytokinesis, actomyosin ring formation|protein localisation to cell division site involved in contractile ring assembly|protein localization to cell division site involved in cytokinesis, contractile ring assembly Any protein localization to cell division site that is involved in cytokinesis, actomyosin contractile ring assembly. GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060393 Any process that modulates the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways. GO:1902576 negative regulation of nuclear cell cycle DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902576 down regulation of DNA replication involved in S phase|inhibition of DNA replication involved in S-phase|downregulation of DNA replication during S phase|downregulation of DNA replication involved in S phase|downregulation of nuclear cell cycle DNA replication|down regulation of DNA replication during S phase|down regulation of nuclear cell cycle DNA replication|inhibition of nuclear cell cycle DNA replication|down-regulation of DNA replication involved in S phase|inhibition of DNA replication during S phase|negative regulation of DNA replication involved in S phase|down regulation of DNA replication involved in S-phase|downregulation of DNA replication involved in S-phase|inhibition of DNA replication involved in S phase|negative regulation of DNA replication during S phase|down-regulation of DNA replication during S phase|down-regulation of DNA replication involved in S-phase|negative regulation of DNA replication involved in S-phase|down-regulation of nuclear cell cycle DNA replication Any process that stops, prevents or reduces the frequency, rate or extent of nuclear cell cycle DNA replication. GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060394 Any process that decreases the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways. GO:1902573 positive regulation of serine-type peptidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902573 activation of serine protease activity|positive regulation of serine protease activity|up regulation of serine protease activity|upregulation of serine-type peptidase activity|up-regulation of serine-type peptidase activity|upregulation of serine protease activity|activation of serine-type peptidase activity|up-regulation of serine protease activity|up regulation of serine-type peptidase activity Any process that activates or increases the frequency, rate or extent of serine-type peptidase activity. GO:0060395 SMAD protein signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060395 The cascade of processes by which a signal interacts with a receptor, causing a change in the activity of a SMAD protein, and ultimately effecting a change in the functioning of the cell. GO:1902574 obsolete negative regulation of leucine import by regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902574 OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in negative regulation of leucine import. GO:0060396 growth hormone receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060396 growth hormone receptor signalling pathway|cellular response to growth hormone|GH receptor signaling pathway The series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand. GO:0035342 positive regulation of inosine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035342 positive regulation of hypoxanthine riboside transport Any process that activates or increases the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0060397 growth hormone receptor signaling pathway via JAK-STAT biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060397 JAK-STAT cascade involved in growth hormone signalling pathway The process in which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of physiological ligands to the growth hormone receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes. GO:1902582 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902582 GO:1902583 obsolete multi-organism intracellular transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902583 multi organism intracellular transport OBSOLETE. An intracellular transport which involves another organism. GO:0035343 negative regulation of inosine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035343 negative regulation of hypoxanthine riboside transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0060398 regulation of growth hormone receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060398 regulation of growth hormone receptor signalling pathway Any process that modulates the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand. GO:0060399 positive regulation of growth hormone receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060399 positive regulation of growth hormone receptor signalling pathway Any process that increases the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand. GO:0035344 hypoxanthine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035344 hypoxanthine transmembrane transport|6-hydroxypurine transport The directed movement of hypoxanthine, 6-hydroxypurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:1902580 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902580 GO:0035345 regulation of hypoxanthine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035345 regulation of 6-hydroxypurine transport Any process that modulates the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:1902581 multi-organism cellular localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902581 multi organism cellular localization A cellular localization which involves another organism. GO:0035346 positive regulation of hypoxanthine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035346 positive regulation of 6-hydroxypurine transport Any process that activates or increases the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0035347 negative regulation of hypoxanthine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035347 negative regulation of 6-hydroxypurine transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0035348 acetyl-CoA transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035348 acetyl-CoA membrane transport The process in which acetyl-CoA is transported across a membrane. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis. GO:0035349 coenzyme A transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035349 coenzyme A membrane transport The process in which coenzyme A is transported across a membrane. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester. GO:0035340 inosine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035340 hypoxanthine riboside transport The directed movement of the purine ribonucleoside inosine, also known as hypoxanthine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0035341 regulation of inosine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035341 regulation of hypoxanthine riboside transport Any process that modulates the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0035339 SPOTS complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035339 serine palmitoyltransferase, Orm1/2, Tsc3 and Sac1 complex A multiprotein complex at least composed of serine palmitoyltransferases and ORM proteins (known as ORMDL proteins in mammals and other higher vertebrates) that plays a key role in sphingolipid homeostasis. GO:1902588 obsolete multi-organism plasmodesmata-mediated intercellular transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902588 multi organism plasmodesmata-mediated intercellular transport OBSOLETE. A plasmodesmata-mediated intercellular transport which involves another organism. GO:0060380 regulation of single-stranded telomeric DNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060380 regulation of telomeric ssDNA binding Any process that modulates the frequency, rate or extent of binding to single-stranded telomeric DNA. GO:1902589 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902589 GO:0060381 positive regulation of single-stranded telomeric DNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060381 positive regulation of telomeric ssDNA binding Any process that increases the frequency, rate or extent of single-stranded telomeric DNA binding. GO:1902586 multi-organism intercellular transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902586 multi organism intercellular transport An intercellular transport which involves another organism. GO:0060382 regulation of DNA strand elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060382 Any process that modulates the rate, frequency or extent of DNA strand elongation. DNA strand elongation is the DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand. GO:1902587 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902587 GO:0060383 positive regulation of DNA strand elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060383 Any process that increases the rate, frequency or extent of DNA strand elongation. DNA strand elongation is the DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand. GO:1902584 positive regulation of response to water deprivation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902584 positive regulation of drought tolerance|upregulation of response to drought|up-regulation of response to dehydration|up-regulation of response to thirst|activation of drought tolerance|activation of response to thirst|upregulation of response to water deprivation|up-regulation of drought tolerance|up regulation of response to drought|upregulation of response to dehydration|activation of response to drought|positive regulation of response to drought|up regulation of response to water deprivation|positive regulation of response to thirst|activation of response to water deprivation|up regulation of response to thirst|upregulation of drought tolerance|up regulation of response to dehydration|activation of response to dehydration|positive regulation of response to dehydration|up-regulation of response to drought|upregulation of response to thirst|up-regulation of response to water deprivation|up regulation of drought tolerance Any process that activates or increases the frequency, rate or extent of response to water deprivation. GO:0060384 innervation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060384 The process in which a nerve invades a tissue and makes functional synaptic connection within the tissue. GO:1902585 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902585 GO:0060385 axonogenesis involved in innervation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060385 The neurite development process that generates a long process of a neuron, as it invades a target tissue. GO:0035331 negative regulation of hippo signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035331 negative regulation of hippo signaling cascade|negative regulation of hippo signalling cascade|negative regulation of hippo signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of hippo signaling. GO:1902593 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902593 GO:0060386 synapse assembly involved in innervation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060386 synapse biogenesis involved in innervation|synaptogenesis involved in innervation The assembly of a synapse within a target tissue in which a nerve is invading. GO:0035332 positive regulation of hippo signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035332 positive regulation of hippo signaling pathway|positive regulation of hippo signalling cascade|positive regulation of hippo signaling cascade Any process that activates or increases the frequency, rate or extent of hippo signaling. GO:1902594 multi-organism nuclear import biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902594 multi organism nuclear import A nuclear import which involves another organism. GO:0060387 fertilization envelope biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0060387 fertilization membrane A structure that lies outside the plasma membrane and surrounds the egg. The fertilization envelope forms from the vitelline membrane after fertilization as a result of cortical granule release. GO:0035333 Notch receptor processing, ligand-dependent biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035333 Notch S2 cleavage|Notch S3 cleavage The proteolytic cleavages to the Notch protein that occur as a result of ligand binding. Ligand binding at the cell surface exposes an otherwise inaccessible cleavage site in the extracellular portion of Notch, which when cleaved releases a membrane-tethered form of the Notch intracellular domain. Subsequent cleavage within the transmembrane domain then leads to the release of the soluble Notch intracellular domain (NICD). GO:1902591 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902591 GO:0060388 vitelline envelope biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0060388 fertilization membrane A glycoprotein-based structure that lies outside the plasma membrane and surrounds the egg before fertilization. GO:1902592 obsolete multi-organism membrane budding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902592 multi organism membrane budding OBSOLETE. A membrane budding which involves another organism. GO:0060389 pathway-restricted SMAD protein phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060389 R-SMAD protein phosphorylation|receptor-regulated SMAD protein phosphorylation|pathway restricted SMAD protein phosphorylation|receptor regulated SMAD protein phosphorylation The process of introducing a phosphate group on to a pathway restricted SMAD protein. A pathway restricted SMAD protein is an effector protein that acts directly downstream of the transforming growth factor family receptor. GO:0035334 Notch receptor processing, ligand-independent biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035334 Notch S1 cleavage The proteolytic cleavages to the Notch protein that occur prior to ligand binding. A primary cleavage event within the extracellular domain whilst the Notch protein in still in the secretory pathway, leads to the transportation of a processed heterodimer to the cell surface. GO:0035335 peptidyl-tyrosine dephosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035335 The removal of phosphoric residues from peptidyl-O-phospho-tyrosine to form peptidyl-tyrosine. GO:0035336 long-chain fatty-acyl-CoA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035336 long-chain fatty acyl CoA metabolic process|long-chain fatty acyl-CoA metabolism The chemical reactions and pathways involving long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more. GO:1902590 multi-organism organelle organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902590 multi organism organelle organization An organelle organization which involves another organism. GO:0035337 fatty-acyl-CoA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035337 fatty acyl CoA metabolic process|fatty-acyl-CoA metabolism The chemical reactions and pathways involving a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group. GO:0035338 long-chain fatty-acyl-CoA biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035338 long-chain fatty-acyl-CoA anabolism|long-chain fatty-acyl-CoA synthesis|long-chain fatty acyl CoA biosynthetic process|long-chain fatty-acyl-CoA biosynthesis|long-chain fatty-acyl-CoA formation The chemical reactions and pathways resulting in the formation of a long-chain fatty-acyl-CoA any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more. GO:0035330 regulation of hippo signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035330 regulation of hippo signalling cascade|regulation of hippo signaling pathway|regulation of hippo signaling cascade Any process that modulates the frequency, rate or extent of hippo signaling. GO:0098983 symmetric, GABA-ergic, inhibitory synapse biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098983 A neuron to neuron synapse that lacks an electron dense postsynaptic specialization, uses GABA as a neurotransmitter and whose activity results in inhibitory postsynaptic potentials. GO:0098984 neuron to neuron synapse biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098984 A synapse in which pre and post-synaptic cells are neurons. GO:0098981 cholinergic synapse biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098981 A synapse that uses acetylcholine as a neurotransmitter. GO:0098982 GABA-ergic synapse biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098982 A synapse that uses GABA as a neurotransmitter. These synapses are typically inhibitory. GO:0098980 presynaptic density biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098980 An electron dense specialization of the presynaptic active zone cytoskeleton. GO:0035328 transcriptionally silent chromatin biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035328 transcriptionally inactive chromatin The ordered and organized complex of DNA and protein that forms regions of the chromosome that are not being actively transcribed. GO:0035329 hippo signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035329 Salvador-Warts-Hippo signaling pathway|hippo signalling cascade|hippo signal transduction|SWH pathway|hippo signaling pathway|hippo signaling cascade The series of molecular signals mediated by the serine/threonine kinase Hippo or one of its orthologs. In Drosophila, Hippo in complex with the scaffold protein Salvador (Sav), phosphorylates and activates Warts (Wts), which in turn phosphorylates and inactivates the Yorkie (Yki) transcriptional activator. The core fly components hippo, sav, wts and mats are conserved in mammals as STK4/3 (MST1/2), SAV1/WW45, LATS1/2 and MOB1. GO:1902599 sulfathiazole transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902599 sulfathiazole transport|sulphathiazole transport The directed movement of sulfathiazole across a membrane. GO:1902597 positive regulation of DNA replication origin binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902597 upregulation of DNA replication origin binding|up regulation of ARS binding|positive regulation of ARS binding|activation of ARS binding|up-regulation of DNA replication origin binding|activation of DNA replication origin binding|up-regulation of ARS binding|up regulation of DNA replication origin binding|upregulation of ARS binding Any process that activates or increases the frequency, rate or extent of DNA replication origin binding. GO:1902598 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902598 GO:1902595 regulation of DNA replication origin binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902595 regulation of ARS binding Any process that modulates the frequency, rate or extent of DNA replication origin binding. GO:1902596 negative regulation of DNA replication origin binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902596 down regulation of ARS binding|down regulation of DNA replication origin binding|downregulation of ARS binding|inhibition of DNA replication origin binding|negative regulation of ARS binding|down-regulation of ARS binding|down-regulation of DNA replication origin binding|inhibition of ARS binding|downregulation of DNA replication origin binding Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication origin binding. GO:0035320 imaginal disc-derived wing hair site selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035320 wing hair site selection|prehair localization Determination of the site in the cell of an imaginal disc-derived wing at which a prehair initiates outgrowth. Restriction of prehair initiation to the distalmost part of a cell is essential to ensure that each wing epithelial cell produces one adult hair that points distally. GO:0035321 maintenance of imaginal disc-derived wing hair orientation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035321 maintenance of wing hair orientation Ensuring that hairs in the imaginal disc-derived wing continue to point distally during development, following the initial establishment of wing hair polarity. GO:0035322 mesenchymal cell migration involved in limb bud formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035322 The orderly movement of a mesenchymal cell from one site to another that will contribute to the formation of a limb bud. GO:0035323 male germline ring canal biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035323 testicular ring canal|spermatocyte ring canal An intercellular bridge that connects the germline cells of a male cyst. GO:0035324 female germline ring canal biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035324 ovarian ring canal|nurse cell ring canal An intercellular bridge that connects the germline cells of a female cyst. GO:0035325 Toll-like receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035325 TLR binding Interacting selectively and non-covalently with a Toll-like protein, a pattern recognition receptor that binds pattern motifs from a variety of microbial sources to initiate an innate immune response. GO:0035326 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035326 GO:0035327 transcriptionally active chromatin biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0035327 The ordered and organized complex of DNA and protein that forms regions of the chromosome that are being actively transcribed. CHEBI:37296 1-alkyl-2-acyl-sn-glycerol 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37296 GO:0098989 NMDA selective glutamate receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098989 A series of molecular signals initiated by glutamate binding to an NMDA-selective glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription. CHEBI:37293 1-ribosylimidazole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37293 GO:0098987 regulation of modification of synapse structure, modulating synaptic transmission biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098987 Any process that regulates the modification of synaptic structure and as a result regulates synaptic transmission. GO:0098988 G protein-coupled glutamate receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0098988 G-protein coupled glutamate receptor activity Combining with glutamate and transmitting a signal from one side of the membrane to the other by activating an associated G-protein, initiating a change in cell activity. GO:0098985 asymmetric, glutamatergic, excitatory synapse biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098985 A neuron to neuron synapse with a postsynaptic density, that uses glutamate as a neurotransmitter and whose activity results in excitatory postsynaptic potentials. GO:0098986 T-bar biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098986 A T-shaped presynpatic density. These are common in arhropod central nervous systems. GO:0098994 disruption of host cell envelope during viral entry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098994 VZ:3938 The disruption of host cell envelope by viral proteins during virus entry. GO:0098995 disruption by virus of host envelope lipopolysaccharide during virus entry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098995 VZ:3939 disassembly by virus of outer membrane lipopolysaccharide during viral entry|degradation of host cell envelope lipopolysaccharide during viral entry|degradation of host lipopolysaccharide during virus entry The breakdown of lipopolysaccharides in a host cell envelope during virus entry into a host cell. For example a phage entering a gram-negative bacterium may actively break down outer membrane lipopolysaccharides. GO:0098992 neuronal dense core vesicle biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098992 A dense core vesicle (granule) that is part of a neuron. These vesicles typically contain neuropeptides. They can be found in all parts of neurons, including the soma, dendrites, axonal swellings (varicosities) and synaptic terminals. GO:0098993 anchored component of synaptic vesicle membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098993 The component of the synaptic vesicle membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. GO:0098990 AMPA selective glutamate receptor signaling pathway biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098990 A series of molecular signals initiated by glutamate binding to an AMPA-selective glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription. GO:0098991 kainate selective glutamate receptor signaling pathway biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098991 A series of molecular signals initiated by glutamate binding to an kainate-selective glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription. CHEBI:144644 a tetracycline zwittterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_144644 CHEBI:144645 an 11a-hydroxytetracyline zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_144645 GO:0035317 imaginal disc-derived wing hair organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035317 imaginal disc-derived wing hair organization and biogenesis|wing hair organization and biogenesis|wing hair organisation|wing trichome organization and biogenesis A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of an imaginal disc-derived wing hair. A wing hair is an actin-rich, polarized, non-sensory apical projection that protrudes from each of the approximately 30,000 wing epithelial cells. An example of this is found in Drosophila melanogaster. GO:0035318 imaginal disc-derived wing hair outgrowth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035318 wing hair outgrowth|wing prehair outgrowth Extrusion of a cellular projection from the apical membrane of an epithelial cell in an imaginal disc-derived wing. Outgrowth initiates approximately 35 hours after puparium formation from the distal side of the cell, and at this stage the cellular extension is termed a prehair. GO:0035319 imaginal disc-derived wing hair elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035319 wing prehair extension|wing hair elongation Growth of a prehair in the approximately 10 hour period following its emergence from an epidermal cell in an imaginal disc-derived wing. Prehair elongation is guided and/or driven by the polymerization of actin filaments and the orderly crosslinking of filaments into bundles. GO:0035310 notum cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035310 The process in which a cell in the larval wing imaginal disc becomes capable of differentiating autonomously into a notum cell, if left in its normal environment. GO:0035311 wing cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035311 The process in which a cell in the larval wing imaginal disc becomes capable of differentiating autonomously into a wing cell, if left in its normal environment. GO:0035312 5'-3' exodeoxyribonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0035312 Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of a DNA molecule. GO:0035313 wound healing, spreading of epidermal cells biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035313 The migration of an epidermal cell along or through a wound gap that contributes to the reestablishment of a continuous epidermis. GO:0035314 scab formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035314 Formation of hardened covering (a scab) at a wound site. The scab has multiple functions including limiting blood loss, providing structural stability to the wound and guarding against infection. GO:0035315 hair cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035315 The process in which a relatively unspecialized cell acquires specialized features of a hair cell. GO:0035316 non-sensory hair organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035316 trichome organisation|non-sensory hair organization and biogenesis|trichome organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of non-sensory hairs. These hairs are polarized cellular extensions that cover much of the insect epidermis. GO:0098998 extrinsic component of postsynaptic early endosome membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098998 The component of the postsynaptic early endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:0098999 extrinsic component of postsynaptic endosome membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098999 The component of the postsynaptic endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:0098996 disruption of host cell glycocalyx during viral entry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098996 VZ:3938 disassembly of glycocalyx during viral entry|catabolism of host glycocalyx during viral entry|degradation of host glycocalyx during viral entry|degradation of host capsule during virus entry The disruption of host cell glycocalyx by viral proteins during virus entry. GO:0098997 fusion of virus membrane with host outer membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098997 VZ:3941 viral envelope fusion with host outer membrane|viral envelope fusion|viral penetration via membrane fusion|fusion of viral membrane with host outer membrane|viral-cell fusion molecule activity Fusion of a viral membrane with the host cell outer membrane during viral entry. CHEBI:76889 (9Z,12Z)-hexadecadienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76889 CHEBI:27911 N(8)-acetylspermidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27911 GO:0050940 regulation of late stripe melanocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050940 regulation of late stripe melanophore differentiation Any process that modulates the frequency, rate or extent of late stripe melanocyte differentiation. CHEBI:27913 L-erythrulose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27913 CHEBI:27914 hydrogenobyrinic acid a,c-diamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27914 GO:0050943 negative regulation of iridophore differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050943 downregulation of iridophore differentiation|down regulation of iridophore differentiation|inhibition of iridophore differentiation|down-regulation of iridophore differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of iridophore differentiation. GO:0050944 negative regulation of xanthophore differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050944 down-regulation of xanthophore differentiation|inhibition of xanthophore differentiation|down regulation of xanthophore differentiation|downregulation of xanthophore differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of xanthophore differentiation. GO:0050941 negative regulation of pigment cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050941 down-regulation of pigment cell differentiation|downregulation of pigment cell differentiation|down regulation of pigment cell differentiation|inhibition of pigment cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of pigment cell differentiation. GO:0050942 positive regulation of pigment cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050942 up-regulation of pigment cell differentiation|activation of pigment cell differentiation|up regulation of pigment cell differentiation|upregulation of pigment cell differentiation|stimulation of pigment cell differentiation Any process that activates or increases the frequency, rate or extent of pigment cell differentiation. CHEBI:27910 7-dehydrodesmosterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27910 GO:0050947 negative regulation of early stripe melanocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050947 down regulation of early stripe melanocyte differentiation|downregulation of early stripe melanocyte differentiation|down-regulation of early stripe melanocyte differentiation|inhibition of early stripe melanocyte differentiation|negative regulation of early stripe melanophore differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of early stripe melanocyte differentiation. GO:0050948 positive regulation of early stripe melanocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050948 upregulation of early stripe melanocyte differentiation|up regulation of early stripe melanocyte differentiation|activation of early stripe melanocyte differentiation|stimulation of early stripe melanocyte differentiation|up-regulation of early stripe melanocyte differentiation|positive regulation of early stripe melanophore differentiation Any process that activates or increases the frequency, rate or extent of early stripe melanocyte differentiation. CHEBI:62241 UDP-N-acetyl-beta-L-fucosamine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62241 GO:0050945 positive regulation of iridophore differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050945 up regulation of iridophore differentiation|upregulation of iridophore differentiation|stimulation of iridophore differentiation|up-regulation of iridophore differentiation|activation of iridophore differentiation Any process that activates or increases the frequency, rate or extent of iridophore differentiation. GO:0050946 positive regulation of xanthophore differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050946 up regulation of xanthophore differentiation|activation of xanthophore differentiation|stimulation of xanthophore differentiation|up-regulation of xanthophore differentiation|upregulation of xanthophore differentiation Any process that activates or increases the frequency, rate or extent of xanthophore differentiation. CHEBI:62244 trans,trans-deca-2,4-dienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62244 CHEBI:62245 UDP-2-acetamido-3-ammonio-2,3-dideoxy-alpha-D-glucuronate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62245 GO:0050949 negative regulation of late stripe melanocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050949 down regulation of late stripe melanocyte differentiation|inhibition of late stripe melanocyte differentiation|down-regulation of late stripe melanocyte differentiation|negative regulation of late stripe melanophore differentiation|downregulation of late stripe melanocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of late stripe melanocyte differentiation. CHEBI:62242 trans-oct-2-enoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62242 CHEBI:62243 trans,trans-octa-2,4-dienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62243 GO:2001152 negative regulation of renal water transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001152 Any process that stops, prevents or reduces the frequency, rate or extent of renal water transport. CHEBI:62248 phenazine-1-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62248 GO:2001153 positive regulation of renal water transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001153 Any process that activates or increases the frequency, rate or extent of renal water transport. GO:2001154 regulation of glycolytic fermentation to ethanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001154 regulation of glucose fermentation to ethanol|regulation of ethanol fermentation Any process that modulates the frequency, rate or extent of glucose catabolic process to ethanol. CHEBI:62246 (S)-2-hydroxypropylphosphonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62246 CHEBI:62247 (1R,2S)-epoxypropylphosphonate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62247 GO:2001155 negative regulation of glycolytic fermentation to ethanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001155 negative regulation of glucose fermentation to ethanol|negative regulation of ethanol fermentation Any process that stops, prevents or reduces the frequency, rate or extent of glucose catabolic process to ethanol. GO:2001156 regulation of proline catabolic process to glutamate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001156 regulation of proline oxidation|regulation of proline breakdown to glutamate|regulation of proline degradation to glutamate Any process that modulates the frequency, rate or extent of proline catabolic process to glutamate. GO:2001157 negative regulation of proline catabolic process to glutamate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001157 negative regulation of proline breakdown to glutamate|negative regulation of proline degradation to glutamate|negative regulation of proline oxidation Any process that stops, prevents or reduces the frequency, rate or extent of proline catabolic process to glutamate. GO:2001158 positive regulation of proline catabolic process to glutamate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001158 positive regulation of proline breakdown to glutamate|positive regulation of proline oxidation|positive regulation of proline degradation to glutamate Any process that activates or increases the frequency, rate or extent of proline catabolic process to glutamate. GO:2001159 regulation of protein localization by the Cvt pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001159 regulation of cytoplasm to vacuole targeting|regulation of cytoplasm-to-vacuole targeting Any process that modulates the frequency, rate or extent of protein localization by the Cvt pathway. CHEBI:76881 EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76881 CHEBI:76882 EC 2.4.99.* (glycosyltransferases transferring other glycosyl groups) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76882 CHEBI:76885 EC 3.4.23.* (aspartic endopeptidase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76885 CHEBI:27915 melamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27915 GO:2001150 positive regulation of dipeptide transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001150 positive regulation of dipeptide membrane transport Any process that activates or increases the frequency, rate or extent of dipeptide transmembrane transport. CHEBI:76883 EC 3.11.1.* (hydrolases acting on C-P bonds of phosphono-acetaldehyde, -acetate, or -pyruvate) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76883 GO:2001151 regulation of renal water transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001151 Any process that modulates the frequency, rate or extent of renal water transport. GO:0050950 positive regulation of late stripe melanocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050950 positive regulation of late stripe melanophore differentiation|up regulation of late stripe melanocyte differentiation|upregulation of late stripe melanocyte differentiation|stimulation of late stripe melanocyte differentiation|activation of late stripe melanocyte differentiation|up-regulation of late stripe melanocyte differentiation Any process that activates or increases the frequency, rate or extent of late stripe melanocyte differentiation. CHEBI:27922 sorbose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27922 GO:0050951 sensory perception of temperature stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050951 sensory perception of thermal stimulus The series of events required for an organism to receive a sensory temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. CHEBI:76898 EC 1.14.14.1 (unspecific monooxygenase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76898 GO:0050954 sensory perception of mechanical stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050954 mechanosensory perception|perception of mechanical stimulus|chemi-mechanical coupling The series of events required for an organism to receive a sensory mechanical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. GO:0050955 thermoception biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050955 Wikipedia:Thermoception thermoreception The series of events required for an organism to receive a temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. Thermoception in larger animals is mainly done in the skin; mammals have at least two types of sensor, for detecting heat (temperatures above body temperature) and cold (temperatures below body temperature). GO:0050952 sensory perception of electrical stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050952 The series of events required for an organism to receive a sensory electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. GO:0050953 sensory perception of light stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050953 The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. GO:0050958 magnetoreception biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050958 Wikipedia:Magnetoception sensory perception of magnetic field|magnetoception The series of events required for an organism to receive a stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. Stimuli may be chemical, mechanical or electrical and interpreting these stimuli allows an organism to determine the orientation of a magnetic field. Magnetoreception also involves the perception of light; birds cannot orient without the presence of short wavelength (blue/green) light. CHEBI:62251 2-(beta-D-glucosyloxy)-cis-cinnamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62251 GO:0050959 echolocation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050959 Wikipedia:Echolocation perception of environment using reflected sound waves Echolocation is the method used by some animals (e.g. bats, dolphins and some whales) to determine the location of something by measuring the time it takes for an echo to return from it. These animals emit sound waves and listen for the echo, calculating the distance to the object from the time lapse between sound emission and the echo returning. GO:0050956 electroception biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050956 Wikipedia:Electroreception electroception sense|electroceptive sense The series of events required for an organism to receive an electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. Many fish possess an electroception sense; for example, the electric eel uses low voltage pulses of electricity for navigation and prey location. GO:0050957 equilibrioception biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050957 Wikipedia:Equilibrioception sensory perception of orientation with respect to gravity The series of events required for an organism to receive an orientational stimulus, convert it to a molecular signal, and recognize and characterize the signal. Equilibrioception refers to a combination of processes by which an organism can perceive its orientation with respect to gravity. In animals, stimuli come from labyrinth system of the inner ears, monitoring the direction of motion; visual stimuli, with information on orientation and motion; pressure receptors, which tell the organism which body surfaces are in contact with the ground; and proprioceptive cues, which report which parts of the body are in motion. CHEBI:62250 UDP-2-acetamido-2-deoxy-alpha-D-ribo-hex-3-uluronate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62250 CHEBI:62254 GDP-alpha-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62254 CHEBI:62259 alpha-L-Fucp-(1->2)-beta-D-Galp-(1->3)-D-GlcpNAc biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62259 GO:2001163 regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001163 Any process that modulates the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues. GO:2001164 negative regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001164 Any process that stops, prevents or reduces the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues. GO:2001165 positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001165 Any process that activates or increases the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues. GO:2001166 regulation of histone H2B ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001166 Any process that modulates the frequency, rate or extent of histone H2B ubiquitination. GO:2001167 negative regulation of histone H2B ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001167 Any process that stops, prevents or reduces the frequency, rate or extent of histone H2B ubiquitination. GO:2001168 positive regulation of histone H2B ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001168 Any process that activates or increases the frequency, rate or extent of histone H2B ubiquitination. GO:2001169 regulation of ATP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001169 regulation of ATP biosynthesis|regulation of ATP anabolism|regulation of ATP synthesis|regulation of ATP regeneration|regulation of ATP formation Any process that modulates the frequency, rate or extent of ATP biosynthetic process. CHEBI:76892 A47934(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76892 CHEBI:76893 EC 3.4.14.2 (dipeptidyl-peptidase II) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76893 CHEBI:76891 EC 3.4.11.14 (cytosol alanyl aminopeptidase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76891 CHEBI:27926 beta-D-xyloside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27926 CHEBI:76896 (11Z)-3-oxooctadecenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76896 GO:2001160 regulation of histone H3-K79 methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001160 regulation of histone lysine H3 K79 methylation|regulation of histone H3 K79 methylation|regulation of histone H3K79me Any process that modulates the frequency, rate or extent of histone H3-K79 methylation. GO:2001161 negative regulation of histone H3-K79 methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001161 negative regulation of histone H3K79me|negative regulation of histone lysine H3 K79 methylation|negative regulation of histone H3 K79 methylation Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K79 methylation. CHEBI:27928 parathion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27928 CHEBI:76894 A41030A(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76894 GO:2001162 positive regulation of histone H3-K79 methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001162 positive regulation of histone H3K79me|positive regulation of histone H3 K79 methylation|positive regulation of histone lysine H3 K79 methylation Any process that activates or increases the frequency, rate or extent of histone H3-K79 methylation. CHEBI:76895 EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76895 GO:0050961 detection of temperature stimulus involved in sensory perception biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050961 sensory perception, sensory detection of heat stimulus|sensory perception, sensory detection of temperature stimulus|sensory detection of temperature stimulus during sensory perception|sensory perception, sensory detection of thermal stimulus|sensory detection of thermal stimulus during sensory perception|sensory detection of temperature stimulus|sensory transduction of temperature stimulus during sensory perception|sensory transduction of thermal stimulus during sensory perception|sensory transduction of temperature stimulus|sensory perception, sensory transduction of heat stimulus|sensory transduction of heat stimulus during sensory perception|sensory perception, sensory transduction of temperature stimulus|sensory detection of heat stimulus during sensory perception|sensory perception, sensory transduction of thermal stimulus The series of events in which a temperature stimulus is received and converted into a molecular signal as part of sensory perception. GO:0050962 detection of light stimulus involved in sensory perception biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050962 sensory perception, sensory detection of light stimulus|sensory detection of light stimulus during sensory perception|sensory detection of light stimulus|sensory transduction of light stimulus during sensory perception|sensory transduction of light stimulus|sensory perception, sensory transduction of light stimulus The series of events in which a light stimulus is received by a cell and converted into a molecular signal as part of the sensory perception of light. GO:0050960 detection of temperature stimulus involved in thermoception biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050960 sensory transduction of thermal stimulus during thermoception|sensory transduction of temperature stimulus during thermoception|sensory detection of thermal stimulus during thermoception|sensory detection of temperature stimulus during thermoception|thermoception, sensory transduction of temperature stimulus|thermoception, sensory detection of temperature stimulus|thermoception, sensory transduction of thermal stimulus|thermoception, sensory detection of thermal stimulus The series of events in which a temperature stimulus is received and converted into a molecular signal as part of thermoception. GO:0050965 detection of temperature stimulus involved in sensory perception of pain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050965 thermal nociception|perception of pain, detection of temperature stimulus|perception of pain, sensory detection of temperature stimulus|sensory perception of pain, sensory detection of thermal stimulus|sensory detection of temperature stimulus during perception of pain|sensory detection of thermal stimulus during sensory perception of pain|sensory transduction of temperature stimulus during perception of pain|sensory transduction of thermal stimulus during sensory perception of pain|perception of pain, sensory transduction of temperature stimulus|sensory perception of pain, sensory transduction of thermal stimulus The series of events involved in the perception of pain in which a temperature stimulus is received and converted into a molecular signal. GO:0050966 detection of mechanical stimulus involved in sensory perception of pain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050966 perception of pain, sensory detection of mechanical stimulus|mechanical nociception|perception of pain, detection of mechanical stimulus|perception of pain, sensory transduction of mechanical stimulus|sensory transduction of mechanical stimulus during perception of pain|sensory detection of mechanical stimulus during perception of pain The series of events involved in the perception of pain in which a mechanical stimulus is received and converted into a molecular signal. PO:0000225 peripheral zone biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000225 zona periférica (Spanish, exact)|peripheral meristem (related)|周辺帯 (Japanese, exact) A portion of meristem tissue (PO:0009013) which is the organogenic region of the meristem, characterized by higher rates of cell division. GO:0050963 detection of electrical stimulus involved in sensory perception biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050963 sensory perception, sensory transduction of electrical stimulus|sensory transduction of electrical stimulus during sensory perception|sensory detection of electrical stimulus during sensory perception|sensory transduction of electrical stimulus|sensory detection of electrical stimulus|sensory perception, sensory detection of electrical stimulus The series of events in which an electrical stimulus is received by a cell and converted into a molecular signal as part of sensory perception. GO:0050964 detection of electrical stimulus involved in electroception biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050964 sensory transduction of electrical stimulus during electroception|sensory detection of electrical stimulus during electroception|electroception, sensory detection of electrical stimulus|electroception, detection of electrical stimulus|detection of electrical stimulus during electroreception|electroception, sensory transduction|electroception, sensory transduction of electrical stimulus The series of events that contribute to electroception in which an electrical stimulus is received and converted into a molecular signal. GO:0050969 detection of chemical stimulus involved in magnetoreception biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050969 magnetoreception, sensory detection of chemical stimulus|magnetoreception, detection of chemical stimulus|magnetoception, sensory transduction of chemical stimulus|sensory transduction of chemical stimulus during magnetoreception|sensory detection of chemical stimulus during magnetoreception|magnetoreception, sensory transduction of chemical stimulus The series of events involved in magnetoception in which a chemical stimulus is received and converted into a molecular signal. It is believed that organisms such as birds and salamanders interpret product ratios in chemical reactions which involve transitions between different spin states. CHEBI:62262 isomultiflorenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62262 PO:0000229 flower meristem biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000229 mersitema floral (Spanish, exact)|floret meristem (narrow)|Poaceae floret meristem (narrow)|floral apical meristem (related)|tassel floret meristem (narrow)|floral meristem (exact)|ear floret meristem (narrow)|花芽分裂組織 (Japanese, exact) A portion of reproductive shoot apical meristem tissue (PO:0008028) that gives rise to the floral organs (PO:0025395). CHEBI:62263 alpha-L-Fucp-(1->2)-beta-D-Galp-(1->4)-D-GlcpNAc biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62263 GO:0050967 detection of electrical stimulus involved in sensory perception of pain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050967 perception of pain, sensory detection of electrical stimulus|perception of pain, detection of electrical stimulus|perception of pain, sensory transduction of electrical stimulus|detection of electrical stimulus during sensory perception of pain|sensory transduction of electrical stimulus during perception of pain|sensory detection of electrical stimulus during perception of pain The series of events that contribute to the perception of pain in which an electrical stimulus is received and converted into a molecular signal. GO:0050968 detection of chemical stimulus involved in sensory perception of pain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050968 sensory detection of chemical stimulus during perception of pain|chemical nociception|perception of pain, sensory detection of chemical stimulus|perception of pain, detection of chemical stimulus|perception of pain, sensory transduction of chemical stimulus|sensory transduction of chemical stimulus during perception of pain The series of events involved in the perception of pain in which a chemical stimulus is received and converted into a molecular signal. CHEBI:86234 alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA(7-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86234 CHEBI:86236 alpha-Kdo-(2->8)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA(8-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86236 CHEBI:62265 beta-D-Galp-(1->3)-[alpha-L-Fucp-(1->4)]-D-GlcpNAc biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62265 GO:2001174 negative regulation of histone H2B conserved C-terminal lysine ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001174 negative regulation of mammalian H2B K120 ubiquitination|negative regulation of fission yeast H2B K119 ubiquitination|negative regulation of budding yeast H2B K123 ubiquitination Any process that stops, prevents or reduces the frequency, rate or extent of histone H2B conserved C-terminal lysine ubiquitination. GO:2001175 positive regulation of histone H2B conserved C-terminal lysine ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001175 positive regulation of mammalian H2B K120 ubiquitination|positive regulation of fission yeast H2B K119 ubiquitination|positive regulation of budding yeast H2B K123 ubiquitination Any process that activates or increases the frequency, rate or extent of histone H2B conserved C-terminal lysine ubiquitination. GO:2001176 regulation of mediator complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001176 Any process that modulates the frequency, rate or extent of mediator complex assembly. GO:2001177 negative regulation of mediator complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001177 Any process that stops, prevents or reduces the frequency, rate or extent of mediator complex assembly. GO:2001178 positive regulation of mediator complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001178 Any process that activates or increases the frequency, rate or extent of mediator complex assembly. GO:2001179 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2001179 GO:2001170 negative regulation of ATP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001170 negative regulation of ATP synthesis|negative regulation of ATP formation|negative regulation of ATP biosynthesis|negative regulation of ATP regeneration|negative regulation of ATP anabolism Any process that stops, prevents or reduces the frequency, rate or extent of ATP biosynthetic process. GO:2001171 positive regulation of ATP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001171 positive regulation of ATP formation|positive regulation of ATP biosynthesis|positive regulation of ATP regeneration|positive regulation of ATP anabolism|positive regulation of ATP synthesis Any process that activates or increases the frequency, rate or extent of ATP biosynthetic process. GO:2001172 positive regulation of glycolytic fermentation to ethanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001172 positive regulation of glucose fermentation to ethanol|positive regulation of ethanol fermentation Any process that activates or increases the frequency, rate or extent of glucose catabolic process to ethanol. GO:2001173 regulation of histone H2B conserved C-terminal lysine ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001173 regulation of fission yeast H2B K119 ubiquitination|regulation of budding yeast H2B K123 ubiquitination|regulation of mammalian H2B K120 ubiquitination Any process that modulates the frequency, rate or extent of histone H2B conserved C-terminal lysine ubiquitination. PO:0000230 inflorescence meristem biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000230 花序分裂組織 (Japanese, exact)|meristema de la inflorescencia (Spanish, exact) A meristem that gives rise to an inflorescence. GO:0050972 detection of mechanical stimulus involved in echolocation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050972 echolocation, detection of mechanical stimulus|sensory transduction of mechanical stimulus during echolocation|sensory detection of mechanical stimulus during echolocation|echolocation, sensory transduction of mechanical stimulus|echolocation, sensory detection of mechanical stimulus The series of events involved in echolocation in which a mechanical stimulus is received and converted into a molecular signal. The stimulus is in the form of a reflected sound wave (an echo), which the organism uses to determine the distance to the object that reflected the sound wave. GO:0050973 detection of mechanical stimulus involved in equilibrioception biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050973 equilibrioception, sensory detection of mechanical stimulus|equilibrioception, detection of mechanical stimulus|equilibrioception, sensory transduction of mechanical stimulus|sensory detection of mechanical stimulus during equilibrioception|sensory transduction of mechanical stimulus during equilibrioception The series of events involved in equilibrioception in which a mechanical stimulus is received and converted into a molecular signal. During equilibrioception, mechanical stimuli may be in the form of input from pressure receptors or from the labyrinth system of the inner ears. GO:0050970 detection of electrical stimulus involved in magnetoreception biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050970 sensory detection of electrical stimulus during magnetoreception|magnetoreception, sensory detection of electrical stimulus|magnetoreception, detection of electrical stimulus|magnetoception, sensory transduction of electrical stimulus|detection of electrical stimulus during magnetoreception|sensory transduction of electrical stimulus during magnetoreception|magnetoreception, sensory transduction of electrical stimulus The series of events that contribute to magnetoception in which an electrical stimulus is received and converted into a molecular signal. The stimulus is in the form of an induced electric field resulting from movement in a magnetic field. CHEBI:27902 tetracycline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27902 GO:0050971 detection of mechanical stimulus involved in magnetoreception biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050971 sensory detection of mechanical stimulus during magnetoreception|magnetoreception, sensory transduction of mechanical stimulus|magnetoreception, sensory detection of mechanical stimulus|magnetoreception, detection of mechanical stimulus|magnetoception, sensory transduction of mechanical stimulus|sensory transduction of mechanical stimulus during magnetoreception The series of events involved in magnetoception in which a mechanical stimulus is received and converted into a molecular signal. The stimulus is in the form of torque on particles such as magnetite which respond to a magnetic field. CHEBI:27903 (2,4,5-trichlorophenoxy)acetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27903 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050976 perception of touch, sensory detection of mechanical stimulus|perception of touch, detection of mechanical stimulus|perception of touch, sensory transduction of mechanical stimulus|sensory detection of mechanical stimulus during perception of touch|tactition, sensory detection of mechanical stimulus|sensory transduction of mechanical stimulus during perception of touch The series of events involved in the perception of touch in which a mechanical stimulus is received and converted into a molecular signal. GO:0050977 magnetoreception by sensory perception of chemical stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050977 magnetoreception, sensory perception of chemical stimulus|magnetoreception, using chemical stimulus|magnetoreception through chemical stimulus|magnetoreception by chemical stimulus The series of events required for an organism to receive a chemical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. It is believed that organisms such as birds and salamanders use a 'chemical compass': chemical reactions that involve transitions between different spin states can be influenced by magnetic fields and by detecting the different product ratios, these organisms can perceive the direction of the magnetic field. The mechanism by which this is detected is not certain but it may also involve light stimuli. GO:0050974 detection of mechanical stimulus involved in sensory perception biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050974 sensory perception, sensory transduction of mechanical stimulus|sensory transduction of mechanical stimulus during sensory perception|sensory detection of mechanical stimulus during sensory perception|sensory transduction of mechanical stimulus|sensory detection of mechanical stimulus|sensory perception, sensory detection of mechanical stimulus The series of events in which a mechanical stimulus is received and converted into a molecular signal as part of sensory perception. GO:0050975 sensory perception of touch biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050975 Wikipedia:Touch taction|tactition|tactile sense|perception of touch The series of events required for an organism to receive a touch stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. The perception of touch in animals is mediated by mechanoreceptors in the skin and mucous membranes and is the sense by which contact with objects gives evidence as to certain of their qualities. Different types of touch can be perceived (for example, light, coarse, pressure and tickling) and the stimulus may be external or internal (e.g. the feeling of a full stomach). GO:0050978 magnetoreception by sensory perception of electrical stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050978 magnetoreception, sensory perception of electrical stimulus|magnetoreception, using electrical stimulus|magnetoreception through electrical stimulus|magnetoreception by electrical stimulus The series of events required for an organism to receive an electrical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. Movement in a magnetic field results in an induced electric field, which can be perceived by organisms such as elasmobranch fish. GO:0050979 magnetoreception by sensory perception of mechanical stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050979 magnetoreception, sensory perception of mechanical stimulus|magnetoreception, using mechanical stimulus|magnetoreception through mechanical stimulus The series of events required for an organism to receive a mechanical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. A magnetic field exerts a torque on a ferromagnetic material (e.g. magnetite) or on a material with diamagnetic anisotropy; organisms that can detect this torque can use it to determine the orientation of the magnetic field. UBERON:0000390 lens nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000390 nucleus of lens The core of the crystalline lens, surrounded by the cortex. GO:2001185 regulation of CD8-positive, alpha-beta T cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001185 Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell activation. CHEBI:86226 lipid IIA(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86226 GO:2001186 negative regulation of CD8-positive, alpha-beta T cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001186 Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell activation. UBERON:0000391 leptomeninx biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000391 leptomeninges|pia-arachnoid|arachnoid mater and pia mater|pia-arachnoid of neuraxis|arachnoidea mater et pia mater pia mater or arachnoid mater. GO:2001187 positive regulation of CD8-positive, alpha-beta T cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001187 Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell activation. GO:2001188 regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001188 regulation of T-lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell|regulation of T-cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell|regulation of T lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell Any process that modulates the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell. GO:2001189 negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001189 negative regulation of T lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell|negative regulation of T-lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell|negative regulation of T-cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell Any process that stops, prevents or reduces the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell. UBERON:0000398 cartilage tissue of sternum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000398 cartilage of sternum Any portion of cartilage tissue that is part of the sternum GO:2001180 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2001180 GO:2001181 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2001181 CHEBI:27904 D-erythrose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27904 GO:2001182 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2001182 UBERON:0000395 cochlear ganglion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000395 vestibulocochlear VIII ganglion cochlear component|ganglion cochlearis|vestibulocochlear ganglion cochlear component|spiral ganglion of cochlea|Corti's ganglion|ganglion spirale cochleae|cochlear part of vestibulocochlear ganglion|ganglion of Corti|spiral ganglion|ganglion spirale The group of nerve cell bodies that conveys auditory sensation from the organ of Corti to the hindbrain and resides on the cochlear part of the vestibulocochlear nerve (eighth cranial nerve)[MP]. distributed to the hair cells of the spiral organ. The cochlear fibers arise in bipolar cells in the spiral ganglion in the modiolus. GO:2001183 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2001183 CHEBI:27906 ubiquinone-0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27906 UBERON:0000397 colonic epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000397 large bowel epithelium|epithelium of large bowel|epithelial tissue of large bowel|large bowel epithelial tissue|epithelium of colon|epithelial tissue of colon|colon epithelial tissue|colon epithelium|posterior intestine epithelium An epithelium that is part of a colon [Automatically generated definition]. GO:2001184 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_2001184 CHEBI:27907 alpha-L-rhamnopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27907 GO:0050983 obsolete deoxyhypusine biosynthetic process from spermidine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050983 EC:2.5.1.46|MetaCyc:2.5.1.46-RXN deoxyhypusine anabolism from spermidine, using deoxyhypusine synthase|deoxyhypusine formation from spermidine, using deoxyhypusine synthase|deoxyhypusine biosynthesis from spermidine, using deoxyhypusine synthase|deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase|[eIF-5A]-deoxyhypusine synthase activity|spermidine catabolic process to deoxyhypusine, using deoxyhypusine synthase|(4-aminobutyl)lysine synthase activity|spermidine breakdown to deoxyhypusine, using deoxyhypusine synthase|spermidine degradation to deoxyhypusine, using deoxyhypusine synthase OBSOLETE. The chemical reactions resulting in the formation of deoxyhypusine from spermidine by the enzyme [eIF-5A]-deoxyhypusine synthase. The reaction occurs in four steps: 1. spermidine + NAD+ = dehydrospermidine + NADH + H+; 2. dehydrospermidine + [enzyme]-lysine = 1,3-diaminopropane + [enzyme]-lysine-N6=CH(CH2)3NH2; 3. [enzyme]-lysine-N6=CH(CH2)3NH2 = [eIF-5A]-lysine-N6=CH(CH2)3NH2; 4. [eIF-5A]-lysine-N6=CH(CH2)3NH2 + NADH + H+ = [eIF-5A]-deoxyhypusine + NAD+. GO:0050984 peptidyl-serine sulfation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050984 RESID:AA0361 The sulfation of peptidyl-serine to form peptidyl-O-sulfo-L-serine. GO:0050981 detection of electrical stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050981 The series of events by which an electrical stimulus is received and converted into a molecular signal. PO:0000289 sieve tube element biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000289 miembro del tubo criboso (Spanish, exact)|師(篩）管要素 (Japanese, exact)|sieve tube segment (exact)|sieve tube member (exact)|sieve-tube element (exact) A sieve element (PO:0025406) that is part of a sieve tube (PO:0025416) and has as parts sieve areas aggregated into sieve plates (GO:0097218). GO:0050982 detection of mechanical stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050982 The series of events by which a mechanical stimulus is received and converted into a molecular signal. GO:0050987 obsolete enzyme active site formation via O-sulfo-L-serine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050987 RESID:AA0361 OBSOLETE. The transient sulfation of peptidyl-serine to form O-sulfo-L-serine. GO:0050988 N-terminal peptidyl-methionine carboxylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050988 RESID:AA0363 The carboxylation of the N-terminal methionine of proteins to form the derivative N-carboxy-L-methionine. GO:0050985 peptidyl-threonine sulfation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050985 RESID:AA0362 The sulfation of peptidyl-threonine to form peptidyl-O-sulfo-L-threonine. GO:0050986 isopeptide cross-linking via N-(L-isoglutamyl)-glycine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050986 RESID:AA0360 The formation of an isopeptide cross-link between peptidyl-glutamate and peptidyl-glycine to produce N-(L-isoglutamyl)-glycine, as found in the antibiotic microcin J25. GO:2001116 methanopterin-containing compound biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001116 methanopterin biosynthesis The chemical reactions and pathways resulting in the formation of a methanopterin. GO:2001117 tetrahydromethanopterin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001117 tetrahydromethanopterin metabolism The chemical reactions and pathways involving a tetrahydromethanopterin. GO:0050989 N-terminal protein amino acid carboxylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050989 The carboxylation of the N-terminal amino acid of proteins. GO:2001118 tetrahydromethanopterin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001118 tetrahydromethanopterin biosynthesis The chemical reactions and pathways resulting in the formation of a tetrahydromethanopterin. GO:2001119 methanofuran metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001119 methanofuran metabolism The chemical reactions and pathways involving a methanofuran. CHEBI:62286 2'-deoxyinosine 5'-diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62286 CHEBI:86258 uridine-5'-aldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86258 CHEBI:62287 alpha-L-Fucp-(1->3)-[beta-D-Galp-(1->4)]-D-GlcpNAc biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62287 GO:0060310 regulation of elastin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060310 regulation of elastin breakdown|regulation of elastin catabolism|regulation of elastin degradation Any process that modulates the rate, frequency or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin. GO:2001110 negative regulation of lens epithelial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001110 Any process that stops, prevents or reduces the frequency, rate or extent of lens epithelial cell proliferation. GO:0060311 negative regulation of elastin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060311 negative regulation of elastin catabolism|negative regulation of elastin degradation|negative regulation of elastin breakdown|down-regulation of elastin catabolic process Any process that decreases the rate, frequency or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin. GO:0060312 regulation of blood vessel remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060312 Any process that modulates the rate, frequency or extent of blood vessel remodeling, the reorganization or renovation of existing blood vessels. GO:2001111 positive regulation of lens epithelial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001111 Any process that activates or increases the frequency, rate or extent of lens epithelial cell proliferation. GO:0060313 negative regulation of blood vessel remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060313 inhibition of blood vessel remodeling|down-regulation of blood vessel remodeling Any process that decreases the rate, frequency or extent of blood vessel remodeling, the reorganization or renovation of existing blood vessels. GO:2001112 regulation of cellular response to hepatocyte growth factor stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001112 regulation of cellular response to HGF stimulus Any process that modulates the frequency, rate or extent of cellular response to hepatocyte growth factor stimulus. GO:0098929 extrinsic component of spine apparatus membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098929 The component of the spine apparatus membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:2001113 negative regulation of cellular response to hepatocyte growth factor stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001113 negative regulation of cellular response to HGF stimulus Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to hepatocyte growth factor stimulus. GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060314 Any process that modulates the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts. GO:2001114 positive regulation of cellular response to hepatocyte growth factor stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001114 positive regulation of cellular response to HGF stimulus Any process that activates or increases the frequency, rate or extent of cellular response to hepatocyte growth factor stimulus. GO:0098927 vesicle-mediated transport between endosomal compartments biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098927 A cellular transport process in which transported substances are moved in membrane-bounded vesicles between endosomal compartments, e.g, between early endosome and sorting endosome. GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060315 Any process that decreases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts. GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060316 Any process that increases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts. GO:2001115 methanopterin-containing compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001115 methanopterin metabolism The chemical reactions and pathways involving a methanopterin. GO:0098928 presynaptic signal transduction biolink:BiologicalProcess go-plus goslim_synapse|gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0098928 presynaptic signaling pathway Signal transduction in which the initial step occurs in a presynapse. GO:0060317 cardiac epithelial to mesenchymal transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060317 heart epithelial to mesenchymal transition A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. GO:0098925 retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098925 Modulation of synaptic transmission by cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by nitric oxide. PO:0000290 tracheary element biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000290 elemento de traqueida (Spanish, exact)|管状要素 (Japanese, exact) A native plant cell (PO:0025606) that has a lignified cell wall with secondary thickening and bordered pits. GO:0098926 postsynaptic signal transduction biolink:BiologicalProcess go-plus goslim_synapse|gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0098926 postsynaptic signaling pathway Signal transduction in which the initial step occurs in a postsynapse. GO:0060318 definitive erythrocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060318 definitive RBC differentiation|definitive red blood cell differentiation|definitive erythropoiesis Erythrocyte differentiation which occurs as part of the process of definitive hemopoiesis. GO:0098923 retrograde trans-synaptic signaling by soluble gas biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098923 Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by an soluble gas ligand. GO:0060319 primitive erythrocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060319 primitive RBC differentiation|primitive red blood cell differentiation|primitive erythropoiesis Erythrocyte differentiation which occurs as part of the process of primitive hemopoiesis. GO:0098924 retrograde trans-synaptic signaling by nitric oxide biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098924 Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by nitric oxide. PO:0000293 guard cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000293 孔辺細胞 (Japanese, exact)|célula guardiana (Spanish, exact)|occlusive cell (exact) One of a pair of cells flanking the stomatal pore. GO:0098921 retrograde trans-synaptic signaling by endocannabinoid biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098921 Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by an endocannabinoid ligand. GO:0050980 detection of light stimulus involved in magnetoreception biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050980 sensory transduction of light stimulus during magnetoreception|magnetoreception, detection of light stimulus|magnetoreception, sensory detection of light stimulus|magnetoreception, sensory transduction of light stimulus|sensory detection of light stimulus during magnetoreception The series of events involved in magnetoception in which a light stimulus is received and converted into a molecular signal. Downstream processing of the light information in addition to other sensory data allows organisms to perceive the orientation of a magnetic field. GO:0098922 extrinsic component of dense core granule membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098922 The component of the dense core granule membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:0098920 retrograde trans-synaptic signaling by lipid biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098920 Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a lipid ligand. GO:0050994 regulation of lipid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050994 regulation of lipid degradation|regulation of lipid breakdown|regulation of lipid catabolism Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids. GO:0050995 negative regulation of lipid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050995 inhibition of lipid catabolic process|negative regulation of lipid catabolism|down regulation of lipid catabolic process|downregulation of lipid catabolic process|negative regulation of lipid degradation|negative regulation of lipid breakdown|down-regulation of lipid catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids. GO:1902508 2-iminoacetate synthase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902508 ThiH-ThiG complex A protein complex which is capable of 2-iminoacetate synthase activity. GO:0050992 dimethylallyl diphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050992 dimethylallyl pyrophosphate biosynthesis|dimethylallyl pyrophosphate biosynthetic process|dimethylallyl diphosphate biosynthesis|dimethylallyl diphosphate anabolism|dimethylallyl diphosphate synthesis|dimethylallyl diphosphate formation|DPP biosynthesis|DPP biosynthetic process The chemical reactions and pathways resulting in the formation of dimethylallyl diphosphate. GO:0050993 dimethylallyl diphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050993 DPP metabolic process|DPP metabolism|dimethylallyl pyrophosphate metabolism|dimethylallyl diphosphate metabolism|dimethylallyl pyrophosphate metabolic process The chemical reactions and pathways involving dimethylallyl diphosphate. GO:1902509 methionine-importing complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902509 methionine importer complex|methionine importing complex A protein complex which is capable of methionine-importing activity. GO:1902506 positive regulation of signal transduction involved in mitotic G2 DNA damage checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902506 upregulation of signal transduction involved in mitotic G2 DNA damage checkpoint|upregulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint|activation of signal transduction involved in mitotic G2 DNA damage checkpoint|up-regulation of signal transduction involved in mitotic G2 DNA damage checkpoint|up regulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint|activation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint|positive regulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint|up regulation of signal transduction involved in mitotic G2 DNA damage checkpoint|up-regulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint Any process that activates or increases the frequency, rate or extent of signal transduction involved in mitotic G2 DNA damage checkpoint. GO:0050998 nitric-oxide synthase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050998 NOS binding Interacting selectively and non-covalently with the enzyme nitric-oxide synthase. GO:1902507 thiazole synthase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902507 A protein complex which is capable of thiazole synthase activity. GO:0050999 regulation of nitric-oxide synthase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050999 NOS regulator|nitric-oxide synthase regulator|regulation of NOS activity Any process that modulates the activity of the enzyme nitric-oxide synthase. GO:0050996 positive regulation of lipid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050996 up-regulation of lipid catabolic process|upregulation of lipid catabolic process|positive regulation of lipid catabolism|positive regulation of lipid degradation|positive regulation of lipid breakdown|up regulation of lipid catabolic process|activation of lipid catabolic process|stimulation of lipid catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids. GO:1902504 regulation of signal transduction involved in mitotic G2 DNA damage checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902504 regulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint Any process that modulates the frequency, rate or extent of signal transduction involved in mitotic G2 DNA damage checkpoint. GO:1902505 negative regulation of signal transduction involved in mitotic G2 DNA damage checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902505 down regulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint|downregulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint|down-regulation of signal transduction involved in mitotic G2 DNA damage checkpoint|negative regulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint|down-regulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint|downregulation of signal transduction involved in mitotic G2 DNA damage checkpoint|inhibition of signal transduction involved in mitotic G2/M transition DNA damage checkpoint|down regulation of signal transduction involved in mitotic G2 DNA damage checkpoint|inhibition of signal transduction involved in mitotic G2 DNA damage checkpoint Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction involved in mitotic G2 DNA damage checkpoint. GO:0050997 quaternary ammonium group binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050997 quaternary amine binding Interacting selectively and non-covalently with a quaternary ammonium group, including glycine betaine, choline, carnitine and proline. A quaternary ammonium group is any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups. GO:2001127 methane biosynthetic process from formic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001127 The chemical reactions and pathways resulting in the formation of a methane from a formic acid. GO:1902502 multivesicular body HOPS complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902502 multivesicular body membrane HOPS complex Any HOPS complex that is part of a multivesicular body membrane. GO:2001128 methane biosynthetic process from methylamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001128 The chemical reactions and pathways resulting in the formation of a methane from a methylamine. GO:1902503 adenylyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902503 ThiF-ThiS complex A protein complex which is capable of adenylyltransferase activity. GO:2001129 methane biosynthetic process from dimethylamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001129 The chemical reactions and pathways resulting in the formation of a methane from a dimethylamine. GO:1902500 vacuolar HOPS complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902500 vacuolar membrane HOPS complex Any HOPS complex that is part of a vacuolar membrane. GO:1902501 lysosomal HOPS complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902501 lysosomal membrane HOPS complex Any HOPS complex that is part of a lysosomal membrane. GO:2001120 methanofuran biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001120 methanofuran biosynthesis The chemical reactions and pathways resulting in the formation of a methanofuran. GO:2001121 coenzyme gamma-F420-2 biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001121 coenzyme gamma-F420-2 biosynthesis The chemical reactions and pathways resulting in the formation of a coenzyme gamma-F420-2. GO:0060300 regulation of cytokine activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060300 Any process that modulates the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells. GO:2001122 maltoheptaose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001122 maltoheptaose metabolism The chemical reactions and pathways involving a maltoheptaose. GO:0060301 positive regulation of cytokine activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060301 Any process that increases the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells. GO:2001123 maltoheptaose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001123 maltoheptaose catabolism The chemical reactions and pathways resulting in the breakdown of a maltoheptaose. GO:0060302 negative regulation of cytokine activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060302 Any process that decreases the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells. GO:2001124 regulation of translational frameshifting biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001124 Any process that modulates the frequency, rate or extent of translational frameshifting. GO:0060303 regulation of nucleosome density biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060303 Any process that modulates the number of nucleosomes in a given region of a chromosome. GO:2001125 negative regulation of translational frameshifting biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001125 Any process that stops, prevents or reduces the frequency, rate or extent of translational frameshifting. GO:0098938 actin cytoskeleton of dendritic spine biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098938 The actin cytoskeleton that is part of a dendritic spine. GO:0060304 regulation of phosphatidylinositol dephosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060304 regulation of phosphoinositide dephosphorylation Any process that modulates the frequency, rate or extent of the chemical reaction involving the removal of one or more phosphate groups from a phosphatidylinositol. GO:0098939 dendritic transport of mitochondrion biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098939 The directed movement of mitochondria along microtubules in nerve cell dendrites. GO:2001126 positive regulation of translational frameshifting biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001126 Any process that activates or increases the frequency, rate or extent of translational frameshifting. GO:0060305 regulation of cell diameter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060305 regulation of cell width Any process that modulates the diameter of a cell, the length of a line segment that crosses through the center of a circular section through a cell. GO:0098936 intrinsic component of postsynaptic membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098936 intrinsic to postsynaptic membrane The component of the postsynaptic membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0060306 regulation of membrane repolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060306 Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential, usually from positive to negative. GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060307 regulation of ventricular cardiac muscle cell repolarization|regulation of ventricular cardiomyocyte membrane repolarization|ventricular repolarization|regulation of ventricular cardiac muscle repolarization|electrocardiogram T wave Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential in a ventricular cardiomyocyte. GO:0098937 anterograde dendritic transport biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098937 The directed movement of organelles or molecules along microtubules from the cell body toward the postsynapse in dendrites. GO:0060308 GTP cyclohydrolase I regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0060308 Modulates the activity of GTP cyclohydrolase I. GTP cyclohydrolase I activity catalyzes the reaction: GTP + 2 H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate. GO:0098934 retrograde dendritic transport biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098934 The directed movement of organelles or molecules along microtubules in a dendrite from the postsynapse towards the cell body. GO:0060309 elastin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060309 elastin catabolism|elastin degradation|elastin breakdown The chemical reactions and pathways resulting in the breakdown of elastin. Elastin is a glycoprotein which is randomly coiled and crosslinked to form elastic fibers that are found in connective tissue. GO:0098935 dendritic transport biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098935 dendrite cargo transport The directed movement of organelles or molecules along microtubules in dendrites. PO:0000282 trichome biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000282 non-secretory trichome (narrow)|capilli (narrow)|bristle (broad)|capillus (narrow)|glochidium (narrow)|cilium (narrow)|squama (narrow)|cilia (narrow)|squamella (narrow)|barb trichome (broad)|lepides (narrow)|lepis (narrow)|glochidia (narrow)|hair (narrow)|setae (related)|squamellae (narrow)|squamae (narrow)|毛茸、糸状体、毛 (Japanese, exact)|scale (narrow)|glochid (narrow)|squamule (narrow)|seta (related)|tricoma (Spanish, exact) A unicellular or multicellular plant structure (PO:0009011) that forms a non-sclerified outgrowth from the epidermis (PO:0005679). GO:0098932 disruption by virus of host cell wall peptidoglycan during virus entry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098932 VZ:3940 degradation of host peptidoglycans during virus entry|degradation of host cell wall peptidoglycan by virus|catabolism of host cell wall peptidoglycan by virus|disassembly by virus of host cell wall peptidoglycan A process carried out by a virus that breaks down peptidoglycans in the cell wall of its host during viral entry. GO:0050990 N-terminal protein amino acid carbamoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050990 N-terminal protein amino acid carbamylation The carbamoylation of the N-terminal amino acid of proteins. GO:0050991 obsolete enzyme active site formation via O-sulfo-L-threonine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050991 RESID:AA0362 OBSOLETE. The transient sulfation of peptidyl-threonine to form O-sulfo-L-threonine. GO:0098933 disruption by symbiont of host cell envelope biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098933 The process by which a symbiont breaks down the cell wall of its host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0098930 axonal transport biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098930 Wikipedia:Axoplasmic_transport axon cargo transport|axoplasmic transport The directed movement of organelles or molecules along microtubules in axons. GO:0098931 virion attachment to host cell flagellum biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098931 VZ:3949 The process by which a virion attaches to a the host cell flagellum. Some DNA bacterial viruses use flagella to attach to the host cell. This contact with the flagellum facilitates concentration of phage particles around the entry receptor on the bacterial cell surface. GO:1902519 response to docetaxel trihydrate biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_1902519 response to docetaxel Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a docetaxel trihydrate stimulus. GO:1902517 glycerol-3-phosphate-transporting ATPase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902517 A protein complex which is capable of glycerol-3-phosphate-transporting ATPase activity. GO:1902518 response to cyclophosphamide biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_1902518 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclophosphamide stimulus. GO:1902515 thioredoxin-disulfide reductase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902515 A protein complex which is capable of thioredoxin-disulfide reductase activity. GO:1902516 sn-glycerol 3-phosphate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1902516 Interacting selectively and non-covalently with sn-glycerol 3-phosphate. GO:2001138 regulation of phospholipid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001138 Any process that modulates the frequency, rate or extent of phospholipid transport. CHEBI:86273 4-hydroxylysine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86273 GO:1902513 regulation of organelle transport along microtubule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902513 regulation of microtubule-based organelle localization Any process that modulates the frequency, rate or extent of organelle transport along microtubule. GO:2001139 negative regulation of phospholipid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001139 Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid transport. GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902514 regulation of generation of L-type calcium current Any process that modulates the frequency, rate or extent of generation of calcium ion transmembrane transport via high voltage-gated calcium channel. CHEBI:86274 N-[(R)-2-hydroxyacyl]phytosphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86274 GO:1902511 negative regulation of apoptotic DNA fragmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902511 down regulation of endonucleolytic DNA catabolic process involved in apoptosis|downregulation of DNA catabolism during apoptosis|downregulation of endonucleolytic DNA catabolic process involved in apoptosis|downregulation of DNA fragmentation involved in apoptotic nuclear change|down-regulation of apoptotic DNA fragmentation|down regulation of DNA fragmentation involved in apoptotic nuclear change|down-regulation of DNA catabolic process during apoptosis|down-regulation of DNA catabolism during apoptosis|negative regulation of DNA catabolic process during apoptosis|negative regulation of DNA catabolism during apoptosis|inhibition of DNA fragmentation involved in apoptotic nuclear change|inhibition of apoptotic DNA fragmentation|negative regulation of endonucleolytic DNA catabolic process involved in apoptosis|down-regulation of endonucleolytic DNA catabolic process involved in apoptosis|inhibition of DNA catabolism during apoptosis|downregulation of DNA catabolic process during apoptosis|inhibition of endonucleolytic DNA catabolic process involved in apoptosis|down regulation of DNA catabolic process during apoptosis|inhibition of DNA catabolic process during apoptosis|down regulation of apoptotic DNA fragmentation|down-regulation of DNA fragmentation involved in apoptotic nuclear change|negative regulation of DNA fragmentation involved in apoptotic nuclear change|down regulation of DNA catabolism during apoptosis|downregulation of apoptotic DNA fragmentation Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic DNA fragmentation. CHEBI:86275 N-(1,2-saturated acyl)phytosphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86275 GO:1902512 positive regulation of apoptotic DNA fragmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902512 upregulation of endonucleolytic DNA catabolic process involved in apoptosis|positive regulation of DNA fragmentation involved in apoptotic nuclear change|up regulation of apoptotic DNA fragmentation|activation of apoptotic DNA fragmentation|up regulation of DNA fragmentation involved in apoptotic nuclear change|up-regulation of DNA catabolic process during apoptosis|up regulation of DNA catabolism during apoptosis|activation of DNA catabolic process during apoptosis|activation of DNA catabolism during apoptosis|positive regulation of DNA catabolism during apoptosis|up regulation of endonucleolytic DNA catabolic process involved in apoptosis|positive regulation of endonucleolytic DNA catabolic process involved in apoptosis|activation of endonucleolytic DNA catabolic process involved in apoptosis|upregulation of DNA fragmentation involved in apoptotic nuclear change|up-regulation of apoptotic DNA fragmentation|positive regulation of DNA catabolic process during apoptosis|up regulation of DNA catabolic process during apoptosis|up-regulation of DNA catabolism during apoptosis|up-regulation of DNA fragmentation involved in apoptotic nuclear change|up-regulation of endonucleolytic DNA catabolic process involved in apoptosis|upregulation of apoptotic DNA fragmentation|activation of DNA fragmentation involved in apoptotic nuclear change|upregulation of DNA catabolism during apoptosis|upregulation of DNA catabolic process during apoptosis Any process that activates or increases the frequency, rate or extent of apoptotic DNA fragmentation. GO:1902510 regulation of apoptotic DNA fragmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902510 regulation of DNA catabolism during apoptosis|regulation of chromatinolysis|regulation of endonucleolytic DNA catabolic process involved in apoptosis|regulation of DNA fragmentation involved in apoptotic nuclear change|regulation of DNA fragmentation|regulation of DNA catabolic process during apoptosis Any process that modulates the frequency, rate or extent of apoptotic DNA fragmentation. PR:000009054 insulin biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000009054 INS An insulin family protein that is a translation product of the human INS gene or a 1:1 ortholog thereof. GO:0060330 regulation of response to interferon-gamma biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060330 regulation of response to type II IFN|regulation of response to gamma-interferon|regulation of response to type II interferon|regulation of response to immune interferon Any process that modulates the rate, frequency or extent of a response to interferon-gamma. Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. GO:2001130 methane biosynthetic process from trimethylamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001130 The chemical reactions and pathways resulting in the formation of a methane from a trimethylamine. GO:0060331 negative regulation of response to interferon-gamma biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060331 negative regulation of response to immune interferon|negative regulation of response to type II interferon|negative regulation of response to type II IFN|negative regulation of response to gamma-interferon Any process that decreases the rate, frequency or extent of a response to interferon-gamma. Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. GO:0060332 positive regulation of response to interferon-gamma biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060332 positive regulation of response to immune interferon|positive regulation of response to type II IFN|positive regulation of response to type II interferon|positive regulation of response to gamma-interferon Any process that increases the rate, frequency or extent of a response to interferon-gamma. Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. GO:2001131 methane biosynthetic process from dimethyl sulfide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001131 The chemical reactions and pathways resulting in the formation of a methane from a dimethyl sulfide. GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098909 Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell contributing to the regulation of its contraction. GO:0060333 interferon-gamma-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060333 immune interferon signaling pathway|type II IFN-mediated signaling pathway|type II interferon-mediated signaling pathway|interferon-gamma-mediated signalling pathway|gamma-interferon-mediated signaling pathway A series of molecular signals initiated by the binding of interferon-gamma to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Interferon gamma is the only member of the type II interferon found so far. GO:2001132 methane biosynthetic process from 3-(methylthio)propionic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001132 The chemical reactions and pathways resulting in the formation of a methane from a 3-(methylthio)propionic acid. GO:2001133 methane biosynthetic process from methanethiol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001133 The chemical reactions and pathways resulting in the formation of a methane from a methanethiol. GO:0060334 regulation of interferon-gamma-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060334 regulation of interferon-gamma-mediated signalling pathway|regulation of type II interferon-mediated signaling pathway|regulation of type II IFN-mediated signaling pathway|regulation of gamma-interferon-mediated signaling pathway|regulation of immune interferon signaling pathway Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of interferon-gamma binding to a cell surface receptor. GO:0098907 regulation of SA node cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098907 regulation of SAN cardiac muscle cell action potential|regulation of sinus node cardiac muscle cell action potential|regulation of SA node cardiac muscle cell action potential|regulation of sinoatrial node cardiac muscle cell action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an SA node cardiac myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. GO:0060335 positive regulation of interferon-gamma-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060335 positive regulation of type II IFN-mediated pathway|positive regulation of interferon-gamma-mediated signalling pathway|positive regulation of type II interferon-mediated signaling pathway|positive regulation of immune interferon-mediated signaling pathway|positive regulation of gamma-interferon-mediated signaling pathway Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of interferon-gamma binding to a cell surface receptor. GO:2001134 methane biosynthetic process from carbon monoxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001134 The chemical reactions and pathways resulting in the formation of a methane from a carbon monoxide. GO:0098908 regulation of neuronal action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098908 generation of action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a neuron. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. GO:0060336 negative regulation of interferon-gamma-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060336 negative regulation of interferon-gamma-mediated signalling pathway|negative regulation of gamma-interferon-mediated signaling pathway|negative regulation of type II IFN-mediated signaling pathway|negative regulation of immune interferon-mediated signaling pathway|negative regulation of type II interferon-mediated signaling pathway Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of interferon-gamma binding to a cell surface receptor. GO:2001135 regulation of endocytic recycling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001135 regulation of retrograde transport of endocytic vesicles Any process that modulates the frequency, rate or extent of endocytic recycling. GO:2001136 negative regulation of endocytic recycling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001136 negative regulation of retrograde transport of endocytic vesicles Any process that stops, prevents or reduces the frequency, rate or extent of endocytic recycling. GO:0060337 type I interferon signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060337 type I interferon-activated signaling pathway|type I interferon-mediated signaling pathway|type I interferon-mediated signalling pathway A series of molecular signals initiated by the binding of a type I interferon to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. GO:0098905 regulation of bundle of His cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098905 regulation of bundle of His cardiac muscle cell action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell of the bundle of His. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. GO:2001137 positive regulation of endocytic recycling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001137 positive regulation of retrograde transport of endocytic vesicles Any process that activates or increases the frequency, rate or extent of endocytic recycling. GO:0098906 regulation of Purkinje myocyte action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098906 Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a Purkinje myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. GO:0060338 regulation of type I interferon-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060338 regulation of type I interferon-mediated signalling pathway Any process that modulates the rate, frequency or extent of a type I interferon-mediated signaling pathway. A type I interferon-mediated signaling pathway is the series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor. GO:0060339 negative regulation of type I interferon-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060339 negative regulation of type I interferon-mediated signalling pathway Any process that decreases the rate, frequency or extent of a type I interferon-mediated signaling pathway. A type I interferon-mediated signaling pathway is the series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor. GO:0098903 regulation of membrane repolarization during action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098903 Any process that modulates the rate, frequency or extent of membrane repolarization during an action potential. Membrane repolarization is the process in which membrane potential changes in the repolarizing direction, towards the resting potential. GO:0098904 regulation of AV node cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098904 regulation of atrioventricular node cardiac muscle cell action potential|regulation of AV node cardiac muscle cell action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrioventricular node myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. GO:0098901 regulation of cardiac muscle cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098901 Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. GO:0098902 regulation of membrane depolarization during action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098902 Any process that modulates the rate, frequency or extent of membrane depolarization during an action potential. Membrane depolarization is the process in which membrane potential changes in the depolarizing direction from the resting potential. PO:0000272 protoxylem biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000272 protoxilema (Spanish, exact)|原生木（質）部 (Japanese, exact)|portion of protoxylem tissue (exact) A portion of primary xylem (PO:0000272) tissue that has as part one or more protoxylem tracheary elements (PO:0025575) embedded in parenchyma (PO:0005421) tissue. GO:0098900 regulation of action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098900 Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. PO:0000256 root hair cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000256 célula del pelo de la raíz (Spanish, exact)|根毛細胞 (Japanese, exact) A root epidermal cell (PO:0025164) that develops from a trichoblast (PO:0000262) and has as part a root hair (GO:0035618). GO:1902528 regulation of protein linear polyubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902528 regulation of M1 linkage Any process that modulates the frequency, rate or extent of protein linear polyubiquitination. GO:1902529 negative regulation of protein linear polyubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902529 downregulation of protein linear polyubiquitination|inhibition of M1 linkage|down-regulation of protein linear polyubiquitination|down-regulation of M1 linkage|negative regulation of M1 linkage|inhibition of protein linear polyubiquitination|downregulation of M1 linkage|down regulation of M1 linkage|down regulation of protein linear polyubiquitination Any process that stops, prevents or reduces the frequency, rate or extent of protein linear polyubiquitination. GO:1902526 negative regulation of protein monoubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902526 downregulation of protein monoubiquitination|down regulation of protein monoubiquitination|down-regulation of protein monoubiquitylation|negative regulation of protein monoubiquitylation|inhibition of protein monoubiquitination|down-regulation of protein monoubiquitinylation|negative regulation of protein monoubiquitinylation|downregulation of protein monoubiquitylation|down regulation of protein monoubiquitylation|downregulation of protein monoubiquitinylation|inhibition of protein monoubiquitylation|down regulation of protein monoubiquitinylation|down-regulation of protein monoubiquitination|inhibition of protein monoubiquitinylation Any process that stops, prevents or reduces the frequency, rate or extent of protein monoubiquitination. CHEBI:86261 (3S)-beta-leucine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86261 GO:1902527 positive regulation of protein monoubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902527 up-regulation of protein monoubiquitinylation|activation of protein monoubiquitinylation|upregulation of protein monoubiquitination|positive regulation of protein monoubiquitylation|up regulation of protein monoubiquitylation|positive regulation of protein monoubiquitinylation|up regulation of protein monoubiquitinylation|up-regulation of protein monoubiquitination|activation of protein monoubiquitination|upregulation of protein monoubiquitylation|upregulation of protein monoubiquitinylation|up regulation of protein monoubiquitination|up-regulation of protein monoubiquitylation|activation of protein monoubiquitylation Any process that activates or increases the frequency, rate or extent of protein monoubiquitination. GO:2001149 negative regulation of dipeptide transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001149 negative regulation of dipeptide membrane transport Any process that stops, prevents or reduces the frequency, rate or extent of dipeptide transmembrane transport. GO:1902524 positive regulation of protein K48-linked ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902524 up regulation of protein K48-linked ubiquitination|up-regulation of protein K48-linked polyubiquitination|activation of protein K48-linked ubiquitination|upregulation of protein K48-linked polyubiquitination|up-regulation of protein K48-linked ubiquitination|up regulation of protein K48-linked polyubiquitination|upregulation of protein K48-linked ubiquitination|positive regulation of protein K48-linked polyubiquitination|activation of protein K48-linked polyubiquitination Any process that activates or increases the frequency, rate or extent of protein K48-linked ubiquitination. CHEBI:86262 D-kynurenine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86262 GO:1902525 regulation of protein monoubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902525 regulation of protein monoubiquitylation|regulation of protein monoubiquitinylation Any process that modulates the frequency, rate or extent of protein monoubiquitination. GO:1902522 response to 4'-epidoxorubicin biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_1902522 response to epirubicin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4'-epidoxorubicin stimulus. CHEBI:86264 rat metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86264 GO:1902523 positive regulation of protein K63-linked ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902523 up regulation of protein K63-linked ubiquitination|up-regulation of protein K63-linked polyubiquitination|activation of protein K63-linked ubiquitination|upregulation of protein K63-linked polyubiquitination|up-regulation of protein K63-linked ubiquitination|up regulation of protein K63-linked polyubiquitination|positive regulation of protein K63-linked polyubiquitination|activation of protein K63-linked polyubiquitination|upregulation of protein K63-linked ubiquitination Any process that activates or increases the frequency, rate or extent of protein K63-linked ubiquitination. CHEBI:86265 N-(1,2-saturated acyl)sphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86265 GO:1902520 response to doxorubicin biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_1902520 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a doxorubicin stimulus. PR:000009064 insulin receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000009064 CD220|IR|INSR A protein that is a translation product of the human INSR gene or a 1:1 ortholog thereof. CHEBI:86266 N-[(2R)-hydroxyacyl]sphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86266 GO:1902521 response to etoposide biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_1902521 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an etoposide stimulus. GO:0060320 rejection of self pollen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060320 The process, involving the sharing and interaction of the single locus incompatibility haplotypes, involved in the rejection of the self pollen by cells in the stigma. GO:2001141 regulation of RNA biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001141 regulation of RNA anabolism|regulation of RNA synthesis|regulation of RNA formation|regulation of RNA biosynthesis Any process that modulates the frequency, rate or extent of RNA biosynthetic process. GO:0035397 helper T cell enhancement of adaptive immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035397 provision of T cell help Positive regulation of an adaptive immune response mediated via cytokine production by helper T cell. GO:0035398 helper T cell enhancement of T cell mediated immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035398 provision of T cell help to T cell|helper T cell enhancement of T cell mediated immunity Positive regulation of a T cell mediated immune response mediated via cytokine production by a helper T cell. GO:0060321 acceptance of pollen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060321 acceptance of non-self pollen|acceptance of self pollen The process, involving the sharing and interaction of the single locus incompatibility haplotypes, involved in the acceptance of pollen by cells in the stigma. GO:2001142 nicotinate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001142 The directed movement of a nicotinateacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0035399 helper T cell enhancement of B cell mediated immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035399 provision of T cell help to B cell|helper T cell enhancement of B cell mediated immunity Positive regulation of a B cell mediated immune response mediated via cytokine production by a helper T cell. GO:2001143 N-methylnicotinate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001143 The directed movement of a N-methylnicotinateacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0060322 head development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060322 The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body. GO:2001144 regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001144 Any process that modulates the frequency, rate or extent of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity. GO:0060323 head morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060323 The process in which the anatomical structures of the head are generated and organized. The head is the anterior-most division of the body. GO:0098918 structural constituent of synapse biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098918 The action of a molecule that contributes to the structural integrity of a synapse. GO:2001145 negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001145 Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity. GO:0060324 face development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060324 The biological process whose specific outcome is the progression of a face from an initial condition to its mature state. The face is the ventral division of the head. GO:2001146 positive regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001146 Any process that activates or increases the frequency, rate or extent of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity. GO:0098919 structural constituent of postsynaptic density biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0098919 The action of a molecule that contributes to the structural integrity of a postsynaptic density. GO:0060325 face morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060325 The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head. GO:0098916 anterograde trans-synaptic signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098916 Cell-cell signaling from pre to post-synapse, across the synaptic cleft. GO:0060326 cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060326 The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). GO:2001147 camalexin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_2001147 3-(1,3-thiazol-2-yl)-1H-indole binding Interacting selectively and non-covalently with camalexin. GO:2001148 regulation of dipeptide transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001148 regulation of dipeptide membrane transport Any process that modulates the frequency, rate or extent of dipeptide transmembrane transport. GO:0060327 cytoplasmic actin-based contraction involved in cell motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060327 The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell from one place to another. GO:0098917 retrograde trans-synaptic signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098917 Cell-cell signaling from post to pre-synapse, across the synaptic cleft. GO:0060328 cytoplasmic actin-based contraction involved in forward cell motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060328 cytoplasmic actin-based contraction involved in forward cell locomotion The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell in the direction that has been defined as the front of the cell. GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098914 atrial repolarization|electrocardiogram QRS complex The process in which ions are transported across a membrane such that the atrial cardiomyocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential. GO:0035390 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0035390 GO:0060329 cytoplasmic actin-based contraction involved in rearward cell motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0060329 cytoplasmic actin-based contraction involved in rearward cell locomotion The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell in the direction that has been defined as the rear of the cell. GO:0098915 membrane repolarization during ventricular cardiac muscle cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098915 ventricular repolarization|regulation of ventricular cardiac muscle repolarization|electrocardiogram T wave The process in which ions are transported across a membrane such that the ventricular cardiomyocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential. GO:0035391 obsolete maintenance of chromatin silencing at silent mating-type cassette biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035391 OBSOLETE. The maintenance of chromatin in a transcriptionally silent state such as heterochromatin at silent mating-type loci. GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098912 atrial cardiac muscle cell depolarization|electrocardiogram PR interval|atrial depolarization The process in which atrial cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential. GO:0098913 membrane depolarization during ventricular cardiac muscle cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098913 electrocardiogram QRS complex|ventricular depolarization The process in which ventricular cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential. GO:0035392 obsolete maintenance of chromatin silencing at telomere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035392 OBSOLETE. The maintenance of chromatin in a transcriptionally silent state such as heterochromatin at the telomere. GO:0035393 chemokine (C-X-C motif) ligand 9 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0035393 CXCL9 production|Monokine induced by gamma interferon production|MIG production The appearance of chemokine (C-X-C motif) ligand 9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0098910 regulation of atrial cardiac muscle cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098910 Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrial cardiac muscle cell contributing to the regulation of its contraction. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. GO:0035394 regulation of chemokine (C-X-C motif) ligand 9 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035394 regulation of MIG production|regulation of CXCL9 production Any process that modulates the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9. GO:0098911 regulation of ventricular cardiac muscle cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098911 Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a ventricular cardiac muscle cell contributing to the regulation of its contraction. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. GO:0035395 negative regulation of chemokine (C-X-C motif) ligand 9 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035395 negative regulation of CXCL9 production|negative regulation of MIG production Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9. PO:0000262 trichoblast biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000262 tricoblasto (Spanish, exact)|根毛形成細胞、トリコブラスト (Japanese, exact)|hair cell (related) A root epidermal cell that is the smaller cell produced by the asymmetric division of an epidermal intial and gives rise to a root hair. GO:0035396 positive regulation of chemokine (C-X-C motif) ligand 9 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0035396 positive regulation of MIG production|positive regulation of CXCL9 production Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9. PO:0000263 non-hair root epidermal cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000263 atricoblasto (Spanish, exact)|非毛根形成細胞、アトリコブラスト (Japanese, exact)|atrichoblast (exact)|non-hair cell (broad) A root epidermal cell (PO:0025164) that develops from an epidermal initial (PO:0000349) and does not have as part a root hair (GO:0035618). GO:2001140 positive regulation of phospholipid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_2001140 Any process that activates or increases the frequency, rate or extent of phospholipid transport. CL:0000927 CD4-positive type I NK T cell secreting interleukin-4 biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000927 CD4-positive type I NK T cell secreting IL-4|CD4-positive type I NK T-cell secreting interleukin-4|CD4-positive type I NK T-lymphocyte secreting interleukin-4|CD4-positive type I NK T lymphocyte secreting interleukin-4|CD4-positive type I NKT cell secreting interleukin-4 A mature NK T cell that predominantly secretes type 2 cytokines such as interleukin-4 and interleukin-13 and enhances type 2 immune responses. CL:0000928 activated CD4-negative, CD8-negative type I NK T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000928 activated CD4-negative, CD8-negative type I NK T-lymphocyte|activated CD4-negative, CD8-negative type I NK T lymphocyte|activated CD4-negative, CD8-negative type I NKT cell|activated CD4-negative, CD8-negative type I NK T-cell A type I NK T cell that has been recently activated, secretes interferon-gamma and interleukin-4, and has phenotype CD4-negative, CD8-negative, CD69-positive, and downregulated NK markers. CL:0000929 CD4-negative, CD8-negative type I NK T cell secreting interferon-gamma biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000929 CD4-negative, CD8-negative type I NK T lymphocyte secreting interferon-gamma|CD4-negative, CD8-negative type I NK T-lymphocyte secreting interferon-gamma|CD4-negative, CD8-negative type I NK T-cell secreting interferon-gamma|CD4-negative, CD8-negative type I NKT cell secreting interferon-gamma|CD4-negative, CD8-negative type I NK T cell secreting IFN-gamma A mature NK T cell that secretes interferon-gamma and enhances Th1 immune responses. CL:0000921 type I NK T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000921 type I NK T-lymphocyte|type I NK T lymphocyte|classical NK T cell|invariant NK T cell|type I NKT cell|type I NK T-cell An alpha-beta T cell expressing NK cell markers that is CD1d restricted and expresses specific V-alpha chains. NK T cells of this type recognize the glycolipid alpha-galactosylceramide in the context of CD1d. CL:0000922 type II NK T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000922 type II NK T lymphocyte|type II NKT cell|type II NK T-cell|type II NK T-lymphocyte An alpha-beta T cell expressing NK call markers that is CD1d restricted and expresses a diverse TCR repertoire. Type II NKT cells do not become activated by alpha-galactosylceramide when presented by CD1d. CL:0000923 CD4-positive type I NK T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000923 CD4-positive type I NK T lymphocyte|CD4-positive type I NKT cell|CD4-positive type I NK T-cell|CD4-positive type I NK T-lymphocyte|NKT.4+.SP A type I NK T cell that has the phenotype CD4-positive. CL:0000924 CD4-negative, CD8-negative type I NK T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000924 CD4-negative, CD8-negative type I NKT cell|CD4-negative, CD8-negative type I NK T-cell|CD4-negative, CD8-negative type I NK T-lymphocyte|CD4-negative, CD8-negative type I NK T lymphocyte|NKT.4-.Sp A type I NK T cell that has the phenotype CD4-negative and CD8-negative. CL:0000925 activated CD4-positive type I NK T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000925 activated CD4-positive type I NK T-cell|activated CD4-positive type I NK T-lymphocyte|activated CD4-positive type I NK T lymphocyte|activated CD4-positive type I NKT cell A type I NK T cell that has been recently activated, secretes interferon-gamma and IL-4, and has the phenotype CD4-positive, CD69-positive, and downregulated NK markers. CL:0000926 CD4-positive type I NK T cell secreting interferon-gamma biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000926 CD4-positive type I NK T cell secreting IFN-gamma|CD4-positive type I NK T-lymphocyte secreting interferon-gamma|CD4-positive type I NK T-cell secreting interferon-gamma|CD4-positive type I NKT cell secreting interferon-gamma|CD4-positive type I NK T lymphocyte secreting interferon-gamma A mature NK T cell that secretes interferon-gamma and enhances type 1 immune responses. GO:0015098 molybdate ion transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015098 molybdate transporter activity Enables the transfer of molybdate (MoO4 2-) ions from one side of a membrane to the other. Molybdate is the bivalent anion derived from molybdic acid. GO:0015099 nickel cation transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015099 RHEA:29831 zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity Enables the transfer of nickel (Ni) cations from one side of a membrane to the other. CHEBI:6650 malic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_6650 GO:0015094 lead ion transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015094 zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity Enables the transfer of lead (Pb) ions from one side of a membrane to the other. GO:0015095 magnesium ion transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015095 Reactome:R-HSA-5336466|Reactome:R-HSA-5339528|Reactome:R-HSA-442661|Reactome:R-HSA-5336453|RHEA:29827|Reactome:R-HSA-5339538|Reactome:R-HSA-5336454 Enables the transfer of magnesium (Mg) ions from one side of a membrane to the other. GO:0015096 obsolete manganese resistance permease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015096 manganese resistance permease activity OBSOLETE. This term was not defined before being made obsolete. GO:0015097 mercury ion transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015097 RHEA:32815 Enables the transfer of mercury (Hg) ions from one side of a membrane to the other. CL:0000930 CD4-negative, CD8-negative type I NK T cell secreting interleukin-4 biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000930 CD4-negative, CD8-negative type I NK T lymphocyte secreting interleukin-4|CD4-negative, CD8-negative type I NKT cell secreting interleukin-4|CD4-negative, CD8-negative type I NK T-cell secreting interleukin-4|CD4-negative, CD8-negative type I NK T-lymphocyte secreting interleukin-4|CD4-negative, CD8-negative type I NK T cell secreting IL-4 A mature NK T cell that secretes interleukin-4 and enhances Th2 immune responses. CL:0000931 activated type II NK T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000931 activated type II NK T lymphocyte|activated type II NK T-cell|activated type II NKT cell|activated type II NK T-lymphocyte A type II NK T cell that has been recently activated, secretes interferon-gamma and interleukin-4, and has the phenotype CD69-positive and downregulated NK markers. CL:0000932 type II NK T cell secreting interferon-gamma biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000932 type II NK T lymphocyte secreting interferon-gamma|type II NK T-lymphocyte secreting interferon-gamma|type II NK T-cell secreting interferon-gamma|type II NKT cell secreting interferon-gamma|type II NK T cell secreting IFN-gamma A type II NK T cell that has been recently activated, secretes interferon-gamma, and has the phenotype CD69-positive and downregulated NK markers. CL:0000933 type II NK T cell secreting interleukin-4 biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000933 type II NK T-lymphocyte secreting interleukin-4|type II NK T cell secreting IL-4|type II NK T lymphocyte secreting interleukin-4|type II NKT cell secreting interleukin-4|type II NK T-cell secreting interleukin-4 A type II NK T cell that has been recently activated, secretes interleukin-4, and has the phenotype CD69-positive and downregulated NK markers. CL:0000934 CD4-positive, alpha-beta cytotoxic T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000934 CD4-positive, alpha-beta cytotoxic T-lymphocyte|CD4-positive, alpha-beta cytotoxic T lymphocyte|CD4-positive, alpha-beta cytotoxic T-cell A CD4-positive, alpha-beta T cell that has cytotoxic function. CL:0000936 early lymphoid progenitor biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000936 ELP|GMLP|lymphoid-primed multipotent progenitor|LMPP A lymphoid progenitor cell that is found in bone marrow, gives rise to B cells, T cells, natural killer cells and dendritic cells, and has the phenotype Lin-negative, Kit-positive, Sca-1-positive, FLT3-positive, CD34-positive, CD150 negative, and GlyA-negative. CL:0000937 pre-natural killer cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000937 pre-NK cell Cell committed to natural killer cell lineage that has the phenotype CD122-positive, CD34-positive, and CD117-positive. This cell type lacks expression of natural killer receptor proteins. GO:0015080 silver ion transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015080 silver transporter activity Enables the transfer of silver (Ag) ions from one side of a membrane to the other. CL:0000906 activated CD8-positive, alpha-beta T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000906 activated CD8-positive, alpha-beta T lymphocyte|activated CD8-positive, alpha-beta T-cell|activated CD8-positive, alpha-beta T-lymphocyte A CD8-positive, alpha-beta T cell with the phenotype CD69-positive, CD62L-negative, CD127-negative, CD25-positive, and CCR7-negative. GO:0015081 sodium ion transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015081 sodium transporter activity Enables the transfer of sodium ions (Na+) from one side of a membrane to the other. CL:0000908 CD8-positive, alpha-beta cytokine secreting effector T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000908 CD8-positive, alpha-beta cytokine secreting effector T-cell|CD8-positive, alpha-beta cytokine secreting effector T-lymphocyte|CD8-positive, alpha-beta cytokine secreting effector T lymphocyte A CD8-positive, alpha-beta T cell with the phenotype CD69-positive, CD62L-negative, CD127-negative, and CD25-positive, that secretes cytokines. GO:0015082 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015082 CL:0000909 CD8-positive, alpha-beta memory T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000909 CD8-positive, alpha-beta memory T-cell|CD8-positive, alpha-beta memory T-lymphocyte|T.8Mem.Sp|CD8-positive, alpha-beta memory T lymphocyte A CD8-positive, alpha-beta T cell that has differentiated into a memory T cell. CHEBI:134090 N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134090 CL:0000900 naive thymus-derived CD8-positive, alpha-beta T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000900 naive thymus-dervied CD8-positive, alpha-beta T lymphocyte|naive CD8+ T cell|T.8Nve.Sp|naive thymus-dervied CD8-positive, alpha-beta T-cell|naive thymus-dervied CD8-positive, alpha-beta T-lymphocyte A CD8-positive, alpha-beta T cell that has not experienced activation via antigen contact and has the phenotype CD45RA-positive, CCR7-positive and CD127-positive. This cell type is also described as being CD25-negative, CD62L-high and CD44-low. CL:0000901 Tr1 cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000901 Tr1 T cell|Tr1 T lymphocyte|T-regulatory T cell type 1|Tr1 T-cell|Tr1 T-lymphocyte CD4-positive alpha-beta T cell with regulatory function that produces IL-10. CHEBI:17608 D-aldohexose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17608 CHEBI:17609 cortisol 21-acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17609 CHEBI:17606 diiodine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17606 CHEBI:17607 1,5-dihydroriboflavin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17607 CHEBI:17604 N(6)-methyl-L-lysine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17604 CHEBI:17605 2-formylbenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17605 CHEBI:17602 4-aminophenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17602 CHEBI:17600 hexadecanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17600 CHEBI:17601 6,7-dimethyl-8-(1-D-ribityl)lumazine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17601 GO:0015076 obsolete heavy metal ion transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015076 heavy metal ion transporter activity OBSOLETE. Enables the directed movement of heavy metal ions into, out of or within a cell, or between cells. Heavy metals are those that can form a coordination bond with a protein, as opposed to an alkali or alkaline-earth metal that can only form an ionic bond; this definition includes the following biologically relevant heavy metals: Cd, Co, Cu, Fe, Hg, Mn, Mo, Ni, V, W, Zn. GO:0015077 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015077 CHEBI:134085 3-hydroxyanthocyanidin cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134085 GO:0015078 proton transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015078 Reactome:R-HSA-170026|Reactome:R-HSA-917841|Reactome:R-HSA-74723|Reactome:R-HSA-164834|Reactome:R-HSA-1222516 hydrogen ion transmembrane transporter activity|proton transporter activity Enables the transfer of a proton from one side of a membrane to the other. GO:0015079 potassium ion transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015079 RHEA:29463 potassium uptake transmembrane transporter activity|potassium transporter activity|potassium uptake permease activity Enables the transfer of potassium ions (K+) from one side of a membrane to the other. GO:0015072 obsolete phosphatidylinositol 3-kinase, class I, catalyst activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015072 phosphatidylinositol 3-kinase, class I, catalyst activity OBSOLETE. Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate. CHEBI:134088 (2S,3R)-flavan-3-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134088 GO:0015073 obsolete phosphatidylinositol 3-kinase, class I, regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015073 phosphatidylinositol 3-kinase, class I, regulator activity OBSOLETE. Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate. CHEBI:134089 (2S,3S)-flavan-3-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134089 GO:0015074 DNA integration biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0015074 The process in which a segment of DNA is incorporated into another, usually larger, DNA molecule such as a chromosome. CHEBI:134086 (2R,3R)-flavan-3-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134086 GO:0015075 ion transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015075 ion transporter activity Enables the transfer of an ion from one side of a membrane to the other. CHEBI:134087 3-hydroxyanthocyanidin betaine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134087 GO:0015090 low-affinity ferric iron ion transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015090 low affinity iron transporter activity|low affinity iron ion transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Fe2+(out) = Fe2+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations. CL:0000916 dendritic epidermal T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000916 DETC|dendritic epidermal T lymphocyte|dendritic epidermal T-cell|dendritic epidermal T-lymphocyte A mature gamma-delta T cell located in the epidermis that regulates wound healing. GO:0015091 ferric iron transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015091 Enables the transfer of ferric iron (Fe(III) or Fe3+) ions from one side of a membrane to the other. GO:0015092 high-affinity ferric iron transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015092 high affinity ferric uptake transmembrane transporter activity Enables the transfer of ferric iron (Fe(III) or Fe3+) ions from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. CL:0000918 Tc2 cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000918 T-cytotoxic T cell type 2|Tc2 T cell|Tc2 T lymphocyte|Th2 CD8-positive T cell|Tc2 T-cell|CD8-positive Th2 cell|Tc2 T-lymphocyte|Th2 non-TFH CD8-positive T cell A CD8-positive, alpha-beta positive T cell expressing GATA-3 and secreting IL-4. GO:0015093 ferrous iron transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015093 RHEA:28486|Reactome:R-HSA-442368|Reactome:R-HSA-5655760|Reactome:R-HSA-1362417 ferrous iron uptake transmembrane transporter activity Enables the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other. CL:0000910 cytotoxic T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000910 cytotoxic T lymphocyte|cytotoxic T-cell|cytotoxic T-lymphocyte A mature T cell that differentiated and acquired cytotoxic function with the phenotype perforin-positive and granzyme-B positive. CL:0000911 effector T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000911 effector T-cell|effector T-lymphocyte|effector T lymphocyte A differentiated T cell with ability to traffic to peripheral tissues and is capable of mounting a specific immune response. CL:0000912 helper T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000912 helper T-cell|helper T-lymphocyte|helper T lymphocyte|T-helper cell A effector T cell that provides help in the form of secreted cytokines to other immune cells. CL:0000914 immature NK T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000914 immature NK T-cell|immature NK T-lymphocyte|immature NKT cell|immature NK T lymphocyte An immature alpha-beta T-cell that express Egr2. These cells give rise to T cells expressing NK markers. CL:0000915 CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000915 CD8-alpha-alpha-positive, alpha-beta intraepithelial T lymphocyte|CD8-alpha-alpha-positive, alpha-beta intraepithelial T-cell|CD8-alpha-alpha-positive, alpha-beta intraepithelial T-lymphocyte An alpha-beta intraepithelial T cell with the phenotype CD8-alpha-alpha-positive located in the columnar epithelium of the gastrointestinal tract. These cells have a memory phenotype of CD2-negative and CD5-negative. GO:0015087 cobalt ion transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015087 RHEA:28578 zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity|cobalt, zinc uptake permease activity Enables the transfer of cobalt (Co) ions from one side of a membrane to the other. GO:0015088 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015088 GO:0015089 high-affinity copper ion transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015089 high affinity copper transporter activity|high affinity copper ion transmembrane transporter activity Enables the transfer of a copper ions (Cu2+) from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. CHEBI:134093 (acetamidomethyl)phosphonate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134093 CHEBI:134099 [(S)-1-acetamidoethyl]phosphonate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134099 GO:0015083 aluminum ion transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015083 aluminium ion transporter activity|aluminium resistance permease activity|aluminum resistance permease activity Enables the transfer of aluminum (Al) ions from one side of a membrane to the other. GO:0015084 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015084 GO:0015085 calcium ion transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015085 Reactome:R-HSA-2534359 Enables the transfer of calcium (Ca) ions from one side of a membrane to the other. CHEBI:6641 (S)-magnoflorine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_6641 GO:0015086 cadmium ion transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015086 zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity|zinc, cadmium uptake permease activity Enables the transfer of cadmium (Cd) ions from one side of a membrane to the other. CHEBI:134098 (S)-(1-aminoethyl)phosphonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134098 GO:0015060 obsolete green-sensitive opsin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015060 green-sensitive opsin OBSOLETE. (Was not defined before being made obsolete). GO:0030699 glycine reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030699 RHEA:12232|EC:1.21.4.2|MetaCyc:RXN-7566|KEGG_REACTION:R07226 acetyl-phosphate ammonia:thioredoxin disulfide oxidoreductase (glycine-forming) Catalysis of the reaction: acetyl phosphate + H(2)O + NH(4)(+) + thioredoxin disulfide = glycine + H(+) + phosphate + thioredoxin. GO:0030697 S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030697 EC:2.1.1.35|RHEA:42712|MetaCyc:TRNA-URACIL-5--METHYLTRANSFERASE-RXN S-adenosyl-L-methionine:tRNA (uracil-5-)-methyltransferase activity|tRNA uracil 5-methyltransferase activity|transfer RNA uracil 5-methyltransferase activity|ribothymidyl synthase activity|transfer RNA uracil methylase activity|M5U-methyltransferase activity|RUMT|RUMT activity|tRNA (uracil-5-)-methyltransferase activity|tRNA:m(5)U54-methyltransferase activity|tRNA:m5U54-methyltransferase activity|S-adenosyl methionine-dependent tRNA (m5U54) methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing thymine at position U54 of a transfer RNA. This occurs in most Gram-negative bacteria, some archae, and eukaryotes. GO:0030698 5,10-methylenetetrahydrofolate-dependent tRNA (m5U54) methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030698 RUMT Catalysis of the transfer of a methyl group from 5,10-methylenetetrahydrofolate to the C5 atom of the uridine residue at position 54 in a tRNA molecule. This occurs in most Gram-positive bacteria and some Gram-negative bacteria. CHEBI:134068 (1->4)-6-phospho-alpha-D-glucan polyanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134068 GO:0015058 obsolete epidermal growth factor-like module containing hormone receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015058 epidermal growth factor-like module containing hormone receptor activity|EGF-like module containing hormone receptor activity|Egr1 hormone receptor OBSOLETE. (Was not defined before being made obsolete). GO:0015059 obsolete blue-sensitive opsin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015059 blue-sensitive opsin OBSOLETE. (Was not defined before being made obsolete). GO:0030695 GTPase regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030695 small GTPase regulator activity|small GTPase regulatory/interacting protein activity Modulates the rate of GTP hydrolysis by a GTPase. GO:0039021 pronephric glomerulus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039021 The progression of the glomerulus of the pronephric kidney over time from its initial formation until its mature state. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment. GO:0015054 gastrin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015054 cholecystokinin-B receptor activity Combining with gastrin and transmitting the signal across the membrane by activating an associated G-protein to initiate a change in cell activity. GO:0030696 tRNA (m5U54) methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030696 RUMT Catalysis of the transfer of a methyl group from a donor to the C5 atom of the uridine residue at position 54 in a tRNA molecule. GO:0015055 secretin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015055 Combining with secretin to initiate a change in cell activity. GO:0039022 pronephric duct development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039022 The process whose specific outcome is the progression of the pronephric duct over time, from its formation to the mature structure. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the pronephric kidney. GO:0030693 obsolete caspase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030693 signaling (initiator) caspase activity|caspase-10 activity|caspase-1 activity|caspase-2 activity|caspase-3 activity|caspase activity|caspase-4 activity|caspase-5 activity|caspase-6 activity|caspase-7 activity|caspase-8 activity|caspase-9 activity|effector caspase activity OBSOLETE. Catalysis of the hydrolysis of a peptide bond on the carboxyl side of an aspartate residue. GO:0015056 corticotrophin-releasing factor receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015056 Combining with the corticotrophin-releasing factor family of ligands, including the urocortins, to initiate a change in cell activity. GO:0030694 bacterial-type flagellum basal body, rod biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030694 flagellin-based flagellum basal body, rod|flagellar basal body, rod The central portion of the bacterial-type flagellar basal body, which spans the periplasm and threads through the rings. GO:0015057 thrombin-activated receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015057 thrombin receptor activity, G-protein coupled|thrombin receptor activity A G protein-coupled receptor activity that is activated by cleavage by thrombin, which exposes a tethered ligand corresponding to the new N-terminus, which binds to the receptor and activates it. GO:0039020 pronephric nephron tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039020 The process whose specific outcome is the progression of a pronephric nephron tubule over time, from its formation to the mature structure. The pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron and connects the filtration unit (glomerulus or glomus) of the pronephros to the pronephric duct. GO:0015050 methane monooxygenase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0015050 A protein complex that possesses methane monooxygenase activity; dimeric and trimeric complexes have been characterized. GO:0030691 Noc2p-Noc3p complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030691 A heterodimer associated with 66S preribosomes; predominantly nucleoplasmic, but also locates to the nucleolus; involved in ribosomal large subunit biogenesis. CHEBI:6698 (-)-matairesinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_6698 GO:0015051 obsolete X-opioid receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015051 X-opioid receptor activity OBSOLETE. Combining with an opioid to initiate a change in cell activity, with the pharmacological characteristics of X-opioid receptors. GO:0030692 Noc4p-Nop14p complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030692 Nop7 complex|Nop7 subcomplex A heterodimer associated with precursors of the eukaryotic small ribosomal subunit, including the 90S preribosome; involved in small subunit biogenesis. CHEBI:6695 (+)-marmesin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_6695 GO:0039023 pronephric duct morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039023 The process in which the anatomical structures of the pronephric duct are generated and organized. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the kidney. CHEBI:134064 N-oleoylserotonin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134064 GO:0015052 beta3-adrenergic receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015052 beta3 adrenoceptor Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta3-adrenergic receptors. GO:0015053 obsolete opsin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015053 opsin OBSOLETE. Hydrophobic glycoprotein to which 11-cis-retinal binds as a Schiff base (in rhodopsin) or 3,4-didehydro-11-cis-retinal binds as a Schiff base in cyanopsin and porphyropsin. GO:0030690 Noc1p-Noc2p complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030690 A heterodimer associated with 90S and 66S preribosomes. Predominantly, but not exclusively, nucleolar; involved in ribosomal large subunit biogenesis. CHEBI:134065 N-stearoylserotonin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134065 GO:0015070 obsolete toxin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015070 toxin activity OBSOLETE. Acts as to cause injury to other living organisms. GO:0015071 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015071 GO:0030688 preribosome, small subunit precursor biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030688 43S preribosome A preribosomal complex consisting of 20S pre-rRNA, ribosomal proteins including late-associating small subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic small ribosomal subunit. GO:0030689 Noc complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0030689 Any of several heterodimers containing one or two Noc proteins, associated with preribosomal complexes; involved in ribosome biogenesis. GO:0030686 90S preribosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030686 A large ribonucleoprotein complex considered to be the earliest preribosomal complex. In S. cerevisiae, it has a size of 90S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins. GO:0030687 preribosome, large subunit precursor biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030687 66S preribosome A preribosomal complex consisting of 27SA, 27SB, and/or 7S pre-rRNA, 5S rRNA, ribosomal proteins including late-associating large subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic large ribosomal subunit. GO:0039018 nephrostome development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039018 The process whose specific outcome is the progression of the nephrostome over time, from its formation to the mature structure. The nephrostome is the opening of the pronephros into the body cavity. GO:0039019 pronephric nephron development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039019 The process whose specific outcome is the progression of the pronephric nephron over time, from its formation to the mature structure. A pronephric nephron is the functional unit of the pronephros. GO:0039016 cell-cell signaling involved in pronephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039016 cell-cell signaling involved in pronephric kidney development|cell-cell signalling involved in pronephros development Any process that mediates the transfer of information from one cell to another and contributes to the progression of the pronephros over time, from its formation to the mature organ. CHEBI:134079 (5Z,8R,9E,11Z,14Z,17Z)-8-hydroperoxyicosapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134079 GO:0039017 pattern specification involved in pronephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039017 pattern specification involved in pronephric kidney development Any developmental process that results in the creation of defined areas or spaces within the pronephros to which cells respond and eventually are instructed to differentiate. GO:0015069 scyllo-inosamine-4-phosphate amidinotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015069 KEGG_REACTION:R03477|MetaCyc:2.1.4.2-RXN|RHEA:13265|EC:2.1.4.2 L-arginine:1-amino-1-deoxy-scyllo-inositol-4-phosphate amidinotransferase activity|L-arginine:inosamine phosphate amidinotransferase activity|inosamine-phosphate amidinotransferase activity|inosamine-P amidinotransferase activity|L-arginine:inosamine-P-amidinotransferase activity Catalysis of the reaction: 1-amino-1-deoxy-scyllo-inositol 4-phosphate + L-arginine = 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + L-ornithine. GO:0030684 preribosome biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0030684 Any complex of pre-rRNAs, ribosomal proteins, and associated proteins formed during ribosome biogenesis. GO:0039010 specification of pronephric distal tubule identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039010 The process in which the distal tubule of the pronephric nephron acquires its identity. GO:0015065 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015065 GO:0015066 alpha-amylase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015066 Stops, prevents or reduces the activity of alpha-amylase. GO:0039011 pronephric proximal tubule morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039011 pronephros proximal tubule morphogenesis The process in which the anatomical structures of a pronephric nephron proximal tubule are generated and organized. A pronephric nephron tubule is an epithelial tube that is part of the pronephros. GO:0030685 nucleolar preribosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030685 Any complex of pre-rRNAs, ribosomal proteins, and associated proteins formed in the nucleolus during ribosome biogenesis. GO:0030682 mitigation of host defenses by symbiont biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030682 avoidance of host defences|evasion or tolerance of host defenses|evasion or tolerance of defense response of other organism involved in symbiotic interaction|evasion or tolerance of defense response of other organism during symbiotic interaction|avoidance of defenses of other organism involved in symbiotic interaction|evasion or tolerance of defenses of other organism|evasion or tolerance of host defense response|evasion or tolerance of defenses of other organism involved in symbiotic interaction|evasion of other organism defence response|avoidance of defenses of other organism during symbiotic interaction|avoidance of host defenses|evasion of host defence response|evasion or tolerance of defenses of other organism during symbiotic interaction A process by which an organism avoids or tolerates the effects of its host organism's defense response. The host defense response is mounted by the host in response to the presence of the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0015067 amidinotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015067 EC:2.1.4.- transamidinase activity Catalysis of the reversible transfer of an amidino group to an acceptor. GO:0015068 glycine amidinotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015068 Reactome:R-HSA-71275|MetaCyc:GLYCINE-AMIDINOTRANSFERASE-RXN|RHEA:13201|EC:2.1.4.1 arginine-glycine amidinotransferase activity|L-arginine:glycine amidinotransferase activity|glycine transamidinase activity|arginine-glycine transamidinase activity Catalysis of the reaction: L-arginine + glycine = L-ornithine + guanidinoacetate. GO:0030683 mitigation of host immune response by virus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030683 evasion or tolerance by virus of host immune response|viral inhibition of intracellular antiviral response|suppression by virus of host extracellular antiviral response|inhibition of extracellular antiviral response|negative regulation of host intracellular antiviral response by virus|suppression of host intracellular antiviral response by virus|negative regulation by virus of extracellular antiviral response|mitigation by virus of host immune response|suppression by virus of host immune response|evasion by virus of host immune response|suppression by virus of host intracellular antiviral response|negative regulation of host extracellular antiviral response by virus|suppression of host extracellular antiviral response by virus|negative regulation by virus of intracellular antiviral response A process by which a virus avoids the effects of the host organism's immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:134072 N-hexadecanoyl-1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134072 GO:0030680 dimeric ribonuclease P complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030680 dimeric RNase P complex A ribonuclease P complex that contains a single RNA molecule that is necessary and usually sufficient for catalysis, and a single protein molecule. Examples of this complex are found in Bacterial species. GO:0015061 obsolete red-sensitive opsin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015061 red-sensitive opsin OBSOLETE. (Was not defined before being made obsolete). GO:0039014 cell differentiation involved in pronephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039014 cell differentiation involved in pronephric kidney development The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephros as it progresses from its formation to the mature state. GO:0039015 cell proliferation involved in pronephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039015 cell proliferation involved in pronephric kidney development The multiplication or reproduction of cells, resulting in the expansion of the population in the pronephros. GO:0015062 obsolete violet-sensitive opsin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015062 violet-sensitive opsin OBSOLETE. (Was not defined before being made obsolete). GO:0030681 multimeric ribonuclease P complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030681 multimeric RNase P complex A ribonuclease P complex that generally contains a single RNA molecule and several protein molecules. Examples of this complex are found in Archaeal species. GO:0039012 pronephric sinus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039012 The process whose specific outcome is the progression of the pronephric sinus over time, from its formation to the mature structure. The pronephric sinus is an ill-defined capillary network that lies between the pronephric tubules. GO:0015063 obsolete long-wave-sensitive opsin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015063 long-wave-sensitive opsin OBSOLETE. An opsin with maximal absorption above 500 nm. GO:0039013 pronephric distal tubule morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039013 The process in which the anatomical structures of a pronephric nephron distal tubule are generated and organized. A pronephric nephron tubule is an epithelial tube that is part of the pronephros. GO:0015064 obsolete UV-sensitive opsin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015064 UV-sensitive opsin OBSOLETE. An opsin with maximal absorption below 400 nm. GO:0030679 cyanelle ribonuclease P complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030679 cyanelle RNase P complex A ribonuclease P complex located in the cyanelle, where it catalyzes the 5' endonucleolytic cleavage of precursor tRNAs to yield mature tRNAs. The best characterized cyanelle ribonuclease P complex, from the alga Cyanophora paradoxa, contains a single RNA molecule that is necessary but not sufficient for catalysis, and several protein molecules. GO:0030677 ribonuclease P complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0030677 RNase P complex A ribonucleoprotein complex that catalyzes cleavage of the leader sequence of precursor tRNAs (pre-tRNAs), generating the mature 5' end of tRNAs. GO:0030678 mitochondrial ribonuclease P complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030678 mitochondrial RNase P complex A ribonuclease P complex located in the mitochondrion of a eukaryotic cell, where it catalyzes the 5' endonucleolytic cleavage of precursor tRNAs to yield mature tRNAs. The subunit composition of mitochondrial ribonuclease P complexes varies between species, but the complex often contains a single RNA molecule and a single protein molecule. GO:0030675 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030675 GO:0030676 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030676 GO:0039007 pronephric nephron morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039007 The process in which the anatomical structures of the pronephric nephron are generated and organized. A pronephric nephron is the functional unit of the pronephros. GO:0039008 pronephric nephron tubule morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039008 The process in which the anatomical structures of a pronephric nephron tubule are generated and organized from an epithelium. A pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron. GO:0039005 specification of pronephric tubule identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039005 The process in which the tubules arranged along the proximal/distal axis of the pronephric nephron acquire their identity. GO:0039006 pronephric nephron tubule formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039006 pronephric tubule formation|pronephros tubule formation The developmental process pertaining to the initial formation of a pronephric nephron tubule from unspecified parts. A pronephric nephron tubule is an epithelial tube that is part of a nephron in the pronephros. GO:0015036 disulfide oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015036 Reactome:R-HSA-1222655|Reactome:R-HSA-264997|Reactome:R-HSA-1222690|Reactome:R-HSA-1222644|Reactome:R-HSA-1222417 disulphide oxidoreductase activity Catalysis of the reaction: substrate with reduced sulfide groups = substrate with oxidized disulfide bonds. GO:0015037 peptide disulfide oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015037 peptide disulphide oxidoreductase activity Catalysis of the reaction: a peptide with reduced sulfide groups = a peptide with oxidized disulfide bonds. GO:0015038 glutathione disulfide oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015038 Reactome:R-HSA-111746 glutaredoxin|glutathione disulphide oxidoreductase activity Catalysis of the reaction: 2 glutathione + electron acceptor = glutathione disulfide + electron donor. GO:0039009 rectal diverticulum development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039009 pronephric rectal diverticulum development The process whose specific outcome is the progression of the rectal diverticulum over time, from its formation to the mature structure. The rectal diverticulum is an outgrowth of the cloaca and links the pronephric kidney to the exterior. GO:0015039 NADPH-adrenodoxin reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015039 RHEA:42312|EC:1.18.1.6|MetaCyc:RXN-13685 NADPH:adrenodoxin oxidoreductase activity|adrenodoxin-type ferredoxin reductase activity|adrenodoxin reductase activity Catalysis of the reaction: oxidized adrenodoxin + NADPH + H+ = reduced adrenodoxin + NADP+. GO:0015032 obsolete storage protein import into fat body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015032 storage protein import by fat body cells|storage protein transport into fat body cells|storage protein import into fat body cells|fat body metabolic process|storage protein uptake into fat body cells|fat body storage protein uptake|import of storage protein into fat body|fat body metabolism OBSOLETE. The incorporation of hemolymph proteins by cells of the fat body of holometabolous insects, during the final larval stage. Uptake of these proteins prepares the insect for pupation and metamorphosis, since insect pupae do not feed and therefore depend on material that has been accumulated during larval life. GO:0030673 axolemma biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030673 NIF_Subcellular:sao250772229|Wikipedia:Axolemma axonal membrane The portion of the plasma membrane surrounding an axon; it is a specialized trilaminar random mosaic of protein molecules floating within a fluid matrix of highly mobile phospholipid molecules, 7-8 nm in thickness. GO:0030674 protein-macromolecule adaptor activity biolink:MolecularActivity go-plus goslim_generic|goslim_chembl|goslim_yeast http://purl.obolibrary.org/obo/GO_0030674 protein-protein adaptor|protein binding, bridging The binding activity of a protein that brings together two or more macromolecules in contact, permitting those molecules to function in a coordinated way. The adaptor can bring together two proteins, or a protein and another macromolecule such as a lipid or a nucleic acid. GO:0015033 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015033 CHEBI:134041 N-octadecanoylglycinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134041 GO:0015034 obsolete cytochrome P450 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015034 cytochrome P450 activity OBSOLETE. A cytochrome b-like protein that has a sulfur atom ligated to the iron of the prosthetic group (heme-thiolate); enzymes: typically monooxygenases acting on, typically, lipophilic substrates. The characteristic mode of action of these enzymes is not electron transfer (some P450 enzymes probably do not even involve the reversible Fe(II)/Fe(III) equilibrium), but rather oxygen atom transfer. GO:0030671 clathrin-coated phagocytic vesicle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030671 The lipid bilayer surrounding a clathrin-coated phagocytic vesicle. GO:0015035 protein disulfide oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015035 MetaCyc:DISULFOXRED-RXN|Reactome:R-HSA-1307802|Reactome:R-HSA-3299753 haem lyase disulphide oxidoreductase activity|protein disulphide oxidoreductase activity|heme lyase disulfide oxidoreductase activity|thioredoxin activity Catalysis of the reaction: a protein with reduced sulfide groups = a protein with oxidized disulfide bonds. GO:0030672 synaptic vesicle membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0030672 The lipid bilayer surrounding a synaptic vesicle. GO:0039003 pronephric field specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039003 pronephric kidney field specification The process in which regions of the embryo are delineated into the area in which the pronephric kidney will develop. GO:0030670 phagocytic vesicle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030670 phagosome membrane The lipid bilayer surrounding a phagocytic vesicle. GO:0039004 specification of pronephric proximal tubule identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039004 The process in which the proximal tubule of the pronephric nephron acquires its identity. CHEBI:134045 polychlorinated dibenzodioxines and related compounds biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134045 GO:0015030 Cajal body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0015030 Wikipedia:Cajal_body|NIF_Subcellular:nlx_subcell_090901 Gemini of coiled bodies|Gems|coiled body A class of nuclear body, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA. CHEBI:134042 N-[(9Z)-hexadecenoyl]glycinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134042 GO:0015031 protein transport biolink:BiologicalProcess go-plus goslim_yeast|goslim_pir|goslim_generic|goslim_chembl http://purl.obolibrary.org/obo/GO_0015031 enzyme transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:134043 phenylureas biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134043 GO:0030668 merozoite dense granule membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030668 The lipid bilayer surrounding a dense granule of the type found in apicomplexan parasites. GO:0030669 clathrin-coated endocytic vesicle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030669 The lipid bilayer surrounding a clathrin-coated endocytic vesicle. GO:0030666 endocytic vesicle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030666 The lipid bilayer surrounding an endocytic vesicle. GO:0030667 secretory granule membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030667 secretory vesicle membrane The lipid bilayer surrounding a secretory granule. GO:0030664 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030664 GO:0030665 clathrin-coated vesicle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030665 clathrin coated vesicle membrane The lipid bilayer surrounding a clathrin-coated vesicle. OBO:GOCHE_59897 substance with EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_59897 CHEBI:134059 N-palmitoylserotonin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134059 CHEBI:134057 (4Z,7Z,11E,13Z,16Z,19Z)-10-hydroperoxydocosahexaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134057 CHEBI:134058 N-palmitoyl dopamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134058 GO:0015047 NADPH-cytochrome-c2 reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015047 RHEA:15237|EC:1.6.2.5|MetaCyc:NADPH--CYTOCHROME-C2-REDUCTASE-RXN cytochrome c2 reductase (reduced nicotinamide adinine dinucleotide phosphate, NADPH)|NADPH:ferricytochrome-c2 oxidoreductase activity|reductase, cytochrome c2 (reduced nicotinamide adenine dinucleotide phosphate) Catalysis of the reaction: NADPH + H+ + 2 ferricytochrome c2 = NADP+ + 2 ferrocytochrome c2. GO:0015048 phthalate dioxygenase reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015048 Catalysis of the transfer of electrons between pyridine nucleotides (obligatory two-electron carriers) and hemes or (2Fe-2S) centers (obligatory one-electron carriers) in respiration, photosynthesis, and many oxygenase systems. GO:0015049 methane monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015049 UM-BBD_enzymeID:e0007|EC:1.14.13.25|MetaCyc:METHANE-MONOOXYGENASE-RXN|KEGG_REACTION:R01143|KEGG_REACTION:R01142 methane,NAD(P)H:oxygen oxidoreductase (hydroxylating)|methane hydroxylase activity Catalysis of the reaction: methane + NAD(P)H + H+ + O2 = methanol + NAD(P)+ + H2O. GO:0030662 coated vesicle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030662 The lipid bilayer surrounding a coated vesicle. CHEBI:134051 (8R,9E,11Z,14Z)-8-hydroperoxyicosatrienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134051 GO:0015043 leghemoglobin reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015043 EC:1.6.2.6|MetaCyc:LEGHEMOGLOBIN-REDUCTASE-RXN ferric leghemoglobin reductase activity|NAD(P)H:ferrileghemoglobin oxidoreductase activity Catalysis of the reaction: NADPH + H+ + 2 ferrileghemoglobin = NADP+ + 2 ferroleghemoglobin. GO:0015044 rubredoxin-NAD+ reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015044 MetaCyc:RUBREDOXIN--NAD+-REDUCTASE-RXN|EC:1.18.1.1|RHEA:18597 NADH--rubredoxin oxidoreductase activity|rubredoxin:NAD+ oxidoreductase activity|DPNH-rubredoxin reductase activity|NADH:rubredoxin reductase activity|dihydronicotinamide adenine dinucleotide--rubredoxin reductase activity|rubredoxin--NAD reductase activity|NADH:rubredoxin oxidoreductase activity|reduced nicotinamide adenine dinucleotide--rubredoxin reductase activity|rubredoxin--nicotinamide adenine dinucleotide reductase activity|NADH--rubredoxin reductase activity Catalysis of the reaction: reduced rubredoxin + NAD+ = oxidized rubredoxin + NADH + H+. GO:0030663 COPI-coated vesicle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030663 COPI coated vesicle membrane The lipid bilayer surrounding a COPI-coated vesicle. CHEBI:134052 (8Z,11Z,14Z)-10-hydroperoxyicosatrienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134052 GO:0015045 rubredoxin-NAD(P)+ reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015045 EC:1.18.1.4|MetaCyc:RUBREDOXIN--NADP+-REDUCTASE-RXN rubredoxin:NAD(P)+ oxidoreductase activity|NADPH:rubredoxin reductase activity|NAD(P)H--rubredoxin oxidoreductase activity|rubredoxin--nicotinamide adenine activity|NAD(P)--rubredoxin oxidoreductase activity|rubredoxin--nicotinamide adenine dinucleotide (phosphate) reductase activity|dinucleotide phosphate reductase activity Catalysis of the reaction: reduced rubredoxin + NAD(P)+ = oxidized rubredoxin + NAD(P)H + H+. GO:0030660 Golgi-associated vesicle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030660 Golgi vesicle membrane The lipid bilayer surrounding a vesicle associated with the Golgi apparatus. GO:0015046 rubredoxin-NADP+ reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015046 RHEA:13949|EC:1.18.1.- Catalysis of the reaction: reduced rubredoxin + NADP+ = oxidized rubredoxin + NADPH + H+. GO:0030661 chitosome membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030661 The lipid bilayer surrounding a chitosome. CHEBI:134055 (9Z,11Z,13S,15Z)-12,13-epoxyoctadecatrienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134055 CHEBI:134056 (5Z,9E,11Z,14Z,17Z)-8-hydroperoxyicosapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134056 GO:0015040 obsolete electron transfer flavoprotein, group I biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015040 electron transfer flavoprotein, group I OBSOLETE. An electron transfer flavoprotein that functions as a housekeeping protein that links acyl-CoA dehydrogenase reactions with the respiratory chain, such as in the fatty acid degradation pathway. GO:0015041 obsolete electron transfer flavoprotein, group II biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015041 electron transfer flavoprotein, group II OBSOLETE. An electron transfer flavoprotein that functions as a housekeeping protein that is synthesized only under certain specific growth conditions and receives electrons from the oxidation of specific substrates, e.g. trimethylamine, carnitine and in nitrogen fixation. CHEBI:134053 (8Z,12E,14Z)-11-hydroperoxyicosatrienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134053 GO:0015042 trypanothione-disulfide reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015042 MetaCyc:1.8.1.12-RXN|EC:1.8.1.12|RHEA:16757 trypanothione-disulphide reductase activity|N(1),N(8)-bis(glutathionyl)spermidine reductase activity|trypanothione reductase activity|trypanothione:NADP+ oxidoreductase activity|NADPH:trypanothione oxidoreductase activity|NADPH2:trypanothione oxidoreductase activity|N1,N8-bis(glutathionyl)spermidine reductase activity Catalysis of the reaction: NADP+ + trypanothione = NADPH + H+ + trypanothione disulfide. CHEBI:134054 (5Z,8R,9Z,11Z,14Z)-8,9-epoxyicosatetraenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134054 CHEBI:42630 propylbenzene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_42630 CHEBI:17668 ribonucleoside diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17668 CHEBI:17666 L-ribulose 5-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17666 CHEBI:17667 3-hydroxy-3-methyl-2-oxobutanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17667 CHEBI:17664 alkylaminium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17664 CHEBI:17665 alpha-D-glucose 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17665 CHEBI:17663 (R)-3-[(R)-3-hydroxybutanoyloxy]butanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17663 CHEBI:17660 N(6)-dimethylallyladenine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17660 CHEBI:17661 GDP-6-deoxy-alpha-D-mannose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17661 CHEBI:27007 tin atom biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27007 CHEBI:27008 tin molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27008 CHEBI:27001 thymidine phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27001 CHEBI:42626 glycyl-AMP zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_42626 CHEBI:17659 UDP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17659 CHEBI:17658 tylosin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17658 CHEBI:17655 4-hydroxy-2-oxopentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17655 CHEBI:17656 (R)-mandelic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17656 CHEBI:17654 electron acceptor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17654 CHEBI:17652 3-hydroxy-L-glutamate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17652 CHEBI:17650 cortisol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17650 CHEBI:17690 (5-L-glutamyl)-L-amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17690 CL:0000985 IgG plasma cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000985 A fully differentiated plasma cell that secretes IgG. CL:0000986 IgM plasma cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000986 A fully differentiated plasma cell that secretes IgM. GO:0040001 establishment of mitotic spindle localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0040001 mitotic spindle positioning|establishment of mitotic spindle localisation|spindle positioning involved in mitotic cell cycle|mitotic spindle positioning or orientation|mitotic spindle positioning and orientation|spindle positioning during mitosis The cell cycle process in which the directed movement of the mitotic spindle to a specific location in the cell occurs. CL:0000987 IgA plasma cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000987 A fully differentiated plasma cell that secretes IgA. GO:0040002 collagen and cuticulin-based cuticle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0040002 collagen and cuticulin-based cuticle biosynthetic process|collagen and cuticulin-based cuticle anabolism|collagen and cuticulin-based cuticle synthesis|collagen and cuticulin-based cuticle formation Synthesis and deposition of a collagen and cuticulin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Caenorhabditis elegans. CL:0000988 hematopoietic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000988 hemopoietic cell|haematopoietic cell|haemopoietic cell A cell of a hematopoietic lineage. CL:0000989 CD11c-low plasmacytoid dendritic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000989 CD11c-low plasmacytoid dendritic cell is a leukocyte that is CD11c-low, CD45R-positive, GR1-positive and CD11b-negative. GO:0040007 growth biolink:BiologicalProcess go-plus gocheck_do_not_annotate|goslim_plant|goslim_pir|goslim_generic|goslim_chembl http://purl.obolibrary.org/obo/GO_0040007 non-developmental growth|growth pattern The increase in size or mass of an entire organism, a part of an organism or a cell. GO:0040008 regulation of growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0040008 Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development. GO:0040009 regulation of growth rate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0040009 Any process that modulates the rate of growth of all or part of an organism. CL:0000980 plasmablast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000980 CD27-positive, CD38-positive, CD20-negative B cell|CD20-negative B cell An activated mature (naive or memory) B cell that is secreting immunoglobulin, typified by being CD27-positive, CD38-positive, CD138-negative. CL:0000981 double negative memory B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000981 double negative memory B-cell|double negative memory B-lymphocyte|dn memory B cell|dn memory B lymphocyte|double negative memory B lymphocyte|dn memory B-cell|dn memory B-lymphocyte A memory B cell with the phenotype IgD-negative and CD27-negative. GO:0040003 chitin-based cuticle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0040003 chitin-based cuticle anabolism|chitin-based cuticle synthesis|chitin-based cuticle formation|chitin-based cuticle biosynthetic process Synthesis and deposition of a chitin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Drosophila melanogaster. GO:0040004 collagen and cuticulin-based cuticle attachment to epithelium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0040004 cuticular attachment to epithelium Attaching of a collagen and cuticulin-based cuticle to the epithelium underlying it. An example of this process is found in Caenorhabditis elegans. CL:0000982 IgG plasmablast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000982 A plasmablast that secretes IgG. GO:0040005 chitin-based cuticle attachment to epithelium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0040005 cuticular attachment to epithelium Attaching of a chitin-containing cuticle to the epithelium underlying it. An example of this process is found in Drosophila melanogaster. CL:0000983 IgM plasmablast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000983 A plasmablast that secretes IgM. CHEBI:17688 (S)-nicotine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17688 GO:0040006 obsolete protein-based cuticle attachment to epithelium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0040006 cuticular attachment to epithelium|protein-based cuticle attachment to epithelium OBSOLETE. Attaching of a protein-based cuticle to the epithelium underlying it. CL:0000984 IgA plasmablast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000984 A plasmablast that secretes IgA. CHEBI:17689 sphingosine-1-phosphocholine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17689 CHEBI:17687 glycocholic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17687 CHEBI:17684 N-formyl-L-glutamate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17684 CHEBI:17685 3-hydroxyquinine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17685 CHEBI:17682 benzoin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17682 CHEBI:17683 UDP-L-iduronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17683 CHEBI:17680 D-glucose 1,6-bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17680 CHEBI:17681 pyridine-2,6-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17681 GO:0040010 positive regulation of growth rate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0040010 up-regulation of growth rate|upregulation of growth rate|up regulation of growth rate|activation of growth rate|stimulation of growth rate Any process that increases the rate of growth of all or part of an organism. GO:0040011 locomotion biolink:BiologicalProcess go-plus goslim_chembl|goslim_pir|goslim_generic http://purl.obolibrary.org/obo/GO_0040011 Self-propelled movement of a cell or organism from one location to another. GO:0040012 regulation of locomotion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0040012 Any process that modulates the frequency, rate or extent of locomotion of a cell or organism. GO:0040013 negative regulation of locomotion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0040013 downregulation of locomotion|down regulation of locomotion|inhibition of locomotion|down-regulation of locomotion Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism. GO:0040018 positive regulation of multicellular organism growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0040018 positive regulation of body growth|positive regulation of body size Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size. GO:0040019 positive regulation of embryonic development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0040019 up regulation of embryonic development|activation of embryonic development|stimulation of embryonic development|up-regulation of embryonic development|upregulation of embryonic development Any process that activates or increases the frequency, rate or extent of embryonic development. CL:0000990 conventional dendritic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000990 dendritic reticular cell|interdigitating cell|type 1 DC|DC1|veiled cell|cDC Conventional dendritic cell is a dendritic cell that is CD11c-high. GO:0040014 regulation of multicellular organism growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0040014 regulation of body size|regulation of body growth Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size. CHEBI:17679 5-hydroxybenzimidazolylcob(I)amide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17679 CL:0000992 immature CD11c-low plasmacytoid dendritic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000992 Immature CD11c-low plasmacytoid dendritic cell is a CD11c-low plasmacytoid dendritic cell that is CD80-low and CD86-low. GO:0040015 negative regulation of multicellular organism growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0040015 negative regulation of body growth|negative regulation of body size Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size. CL:0000993 mature CD11c-low plasmacytoid dendritic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000993 Mature CD11c-low plasmacytoid dendritic cell is a CD11c-low plasmacytoid dendritic cell that is CD83-high and is CD80-positive, CD86-positive, and MHCII-positive. GO:0040016 embryonic cleavage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0040016 The first few specialized divisions of an activated animal egg. CHEBI:17677 CTP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17677 GO:0040017 positive regulation of locomotion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0040017 upregulation of locomotion|stimulation of locomotion|up-regulation of locomotion|activation of locomotion|up regulation of locomotion Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism. CL:0000995 CD34-positive, CD38-positive common myeloid progenitor OR CD34-positive, CD38-positive common lymphoid progenitor biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000995 CD71-positive common myeloid precursor OR CD7-negative lymphoid precursor OR CD7-positive lymphoid CHEBI:17678 2'-hydroxyformononetin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17678 CHEBI:17675 Watasenia luciferin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17675 CHEBI:17676 2-(beta-D-glucopyranosyluronic acid)-D-glucuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17676 CHEBI:17671 5-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17671 CHEBI:17672 carbamoyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17672 CHEBI:17670 1,2-diacyl-3-O-(alpha-D-glucosyl)-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17670 CL:0000963 Bm3-delta B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000963 Bm3-delta B-lymphocyte|Bm3-delta B lymphocyte|Bm3-delta B-cell A germinal center B cell that develops from a Bm3 B cell. This cell has the phenotype IgM-negative, IgD-positive, and CD38-positive. GO:0040021 hermaphrodite germ-line sex determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0040021 The determination of sex and sexual phenotype in the germ line of a hermaphrodite. GO:0040022 feminization of hermaphroditic germ-line biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0040022 The determination of female sex and sexual phenotype in the germ-line of the hermaphrodite. CL:0000964 Bm2' B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000964 Bm2-prime B-lymphocyte|Bm2' B-cell|Bm2-prime B cell|germinal center founder cell|Bm2' B lymphocyte A germinal center B cell that founds a germinal center, and has the phenotype IgD-positive, CD38-positive, and CD23-negative. CL:0000965 Bm3 B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000965 Bm3 B lymphocyte|centroblast|Bm3 B-cell|Bm3 B-lymphocyte A germinal center B cell that is rapidly dividing and has the phenotype IgD-negative, CD38-positive, and CD77-positive. Somatic hypermutation of the immunoglobulin V gene region can occur during proliferation of this cell type. GO:0040023 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0040023 CL:0000966 Bm4 B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000966 Bm4 B lymphocyte|centrocyte|Bm4 B-cell|Bm4 B-lymphocyte A germinal center B cell that has the phenotype CD77-negative, IgD-negative, and CD38-positive. These cells have undergone somatic mutation of the B cell receptor. GO:0040024 dauer larval development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0040024 The process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding. CL:0000967 Bm5 B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000967 Bm5 B lymphocyte|Bm5 B-cell|Bm5 B-lymphocyte A memory B cell arising in the germinal center that is IgD-negative and has undergone somatic mutation of the variable region of the immunoglobulin heavy and light chain genes. CL:0000968 Be cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000968 effector B-lymphocyte|B effector cell|effector B cell|effector B lymphocyte|effector B-cell A mature B cell that produces cytokines that can influence CD4 T cell differentiation. GO:0040020 regulation of meiotic nuclear division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0040020 regulation of meiosis Any process that modulates the frequency, rate or extent of meiotic nuclear division, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes. GO:0040029 regulation of gene expression, epigenetic biolink:BiologicalProcess go-plus goslim_plant http://purl.obolibrary.org/obo/GO_0040029 Any process that modulates the frequency, rate or extent of gene expression; the process is mitotically or meiotically heritable, or is stably self-propagated in the cytoplasm of a resting cell, and does not entail a change in DNA sequence. CHEBI:17628 2-aminoacetaldehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17628 CHEBI:17626 citraconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17626 CHEBI:17627 ferroheme b biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17627 GO:0040025 vulval development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0040025 The process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult. CHEBI:17624 dolichyl beta-D-mannosyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17624 GO:0040026 positive regulation of vulval development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0040026 activation of vulval development|up regulation of vulval development|upregulation of vulval development|up-regulation of vulval development|stimulation of vulval development Any process that activates or increases the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult. CL:0000960 T3 B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000960 transitional stage 3 B cell|T3 B-cell|T3 B-lymphocyte|T3 B lymphocyte|An1 B cell A transitional stage B cell that expresses surface IgM and IgD, and CD62L. This cell type appears to be an anergic B cell that does not proliferate upon BCR signaling, is found in the spleen and lymph nodes, and has the phenotype surface IgM-positive, surface IgD-positive, CD21-positive, CD23-positive, CD62L-positive, and CD93-positive. This cell type has also been described as IgM-low, CD19-positive, B220-positive, AA4-positive, and CD23-positive (i.e. this cell-type is distinguished from T2 cells by surface expression of IgM). CHEBI:17625 dUTP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17625 GO:0040027 negative regulation of vulval development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0040027 downregulation of vulval development|down regulation of vulval development|inhibition of vulval development|down-regulation of vulval development Any process that stops, prevents, or reduces the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult. CL:0000961 Bm1 B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000961 Bm1 B-cell|Bm1 B-lymphocyte|Bm1 B lymphocyte A follicular B cell that is IgD-positive, CD23-negative, and CD38-negative. This naive cell type is activated in the extrafollicular areas through interaction with interdigitating dendritic cells and antigen-specific CD4-positive T cells. CHEBI:17622 dUMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17622 CL:0000962 Bm2 B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000962 Bm2 B lymphocyte|Bm2 B-cell|Bm2 B-lymphocyte A follicular B cell that is IgD-positive and CD23-positive and CD38-positive. This naive cell type is activated in the extrafollicular areas via interaction with dendritic cells and antigen specific T cells. CHEBI:17623 cyclomaltodextrin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17623 GO:0040028 regulation of vulval development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0040028 Any process that modulates the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult. CHEBI:17620 ferulic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17620 CHEBI:17621 FMN biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17621 GO:0040032 post-embryonic body morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0040032 The process in which the anatomical structures of the post-embryonic soma are generated and organized. CL:0000974 long lived plasma cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000974 A fully differentiated plasma cell that lives for years, as opposed to months, secretes immunoglobulin, and has the phenotype weakly CD19-positive, CD20-negative, CD38-negative, strongly CD138-positive, MHC Class II-negative, surface immunoglobulin-negative, IgD-negative, and strongly CXCR4-positive. The majority of these cells of this type reside in the bone marrow. CL:0000975 short lived plasma cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000975 A fully differentiated plasma cell that lives for months. GO:0040033 negative regulation of translation, ncRNA-mediated biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0040033 down-regulation of mRNA translation, ncRNA-mediated|downregulation of mRNA translation, ncRNA-mediated|down regulation of mRNA translation, ncRNA-mediated|inhibition of mRNA translation, ncRNA-mediated Any process, mediated by small non-coding RNAs, that stops, prevents or reduces the rate that mRNAs are effectively translated into protein. GO:0040034 regulation of development, heterochronic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0040034 temporal regulation of development|heterochronic regulation of development|developmental timing Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and the rate at which this time point is reached. CL:0000976 IgA short lived plasma cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000976 A short lived plasma cell that secretes IgA. These cells may be found in the bone marrow as well as in the mucosal immune system. GO:0040035 hermaphrodite genitalia development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0040035 The process whose specific outcome is the progression of the hermaphrodite genitalia over time, from formation to the mature structures. CL:0000977 IgG short lived plasma cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000977 A short lived plasma cell that secretes IgG. CL:0000978 IgM short lived plasma cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000978 A short lived plasma cell that secretes IgM. CL:0000979 IgG memory B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000979 IgG memory B lymphocyte|memory IgG B-cell|memory IgG B-lymphocyte|memory IgG B cell|IgG memory B-cell|memory IgG B lymphocyte|IgG memory B-lymphocyte An IgG memory B cell is a class switched memory B cell that is class switched and expresses IgG on the cell surface. GO:0040030 regulation of molecular function, epigenetic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0040030 regulation of protein activity, epigenetic Any heritable epigenetic process that modulates the frequency, rate or extent of protein function by self-perpetuating conformational conversions of normal proteins in healthy cells. This is distinct from, though mechanistically analogous to, disease states associated with prion propagation and amyloidogenesis. A single protein, if it carries a glutamine/asparagine-rich ('prion') domain, can sometimes stably exist in at least two distinct physical states, each associated with a different phenotype; propagation of one of these traits is achieved by a self-perpetuating change in the protein from one form to the other, mediated by conformational changes in the glutamine/asparagine-rich domain. Prion domains are both modular and transferable to other proteins, on which they can confer a heritable epigenetic alteration of function; existing bioinformatics data indicate that they are rare in non-eukarya, but common in eukarya. CHEBI:17619 4-(3-methylbut-2-enyl)-L-tryptophan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17619 GO:0040031 snRNA modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0040031 The covalent alteration of one or more nucleotides within snRNA, resulting in a change in the properties of the snRNA. CHEBI:17617 L-fuculose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17617 CHEBI:17618 bis-D-fructose 2',1:2,1'-dianhydride biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17618 CHEBI:17615 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17615 CHEBI:17616 all-trans-retinyl palmitate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17616 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0040036 regulation of FGF receptor signaling pathway|regulation of FGFR signaling pathway|regulation of FGF receptor signalling pathway Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity. CL:0000970 unswitched memory B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000970 IgD+ memory B cell|unswitched memory B-cell|unswitched memory B-lymphocyte|non-class-switched memory B cell|unswitched memory B lymphocyte An unswitched memory B cell is a memory B cell that has the phenotype IgM-positive, IgD-positive, CD27-positive, CD138-negative, IgG-negative, IgE-negative, and IgA-negative. CHEBI:17613 all-trans-heptaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17613 CHEBI:17614 5-methyltetrahydropteroyltri-L-glutamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17614 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0040037 inhibition of fibroblast growth factor receptor signaling pathway|negative regulation of FGF receptor signalling pathway|negative regulation of FGFR signaling pathway|down regulation of fibroblast growth factor receptor signaling pathway|downregulation of fibroblast growth factor receptor signaling pathway|down-regulation of fibroblast growth factor receptor signaling pathway|negative regulation of FGF receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity. CL:0000971 IgM memory B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000971 memory IgM B-cell|IgM memory B-cell|memory IgM B-lymphocyte|IgM memory B-lymphocyte|memory IgM B cell|memory IgM B lymphocyte|IgM memory B lymphocyte An IgM memory B cell is an unswitched memory B cell with the phenotype IgM-positive and IgD-negative. CL:0000972 class switched memory B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000972 class switched memory B-lymphocyte|class switched memory B lymphocyte|class switched memory B-cell A class switched memory B cell is a memory B cell that has undergone Ig class switching and therefore is IgM-negative on the cell surface. These cells are CD27-positive and have either IgG, IgE, or IgA on the cell surface. GO:0040038 polar body extrusion after meiotic divisions biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0040038 The cell cycle process in which two small cells are generated, as byproducts destined to degenerate, as a result of the first and second meiotic divisions of a primary oocyte during its development to a mature ovum. One polar body is formed in the first division of meiosis and the other in the second division; at each division, the cytoplasm divides unequally, so that the polar body is of much smaller size than the developing oocyte. At the second division in which a polar body is formed, the polar body and the developing oocyte each contain a haploid set of chromosomes. CHEBI:17611 3-hydroxycyclohexanone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17611 CL:0000973 IgA memory B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000973 IgA memory B lymphocyte|memory IgA B cell|memory IgA B lymphocyte|IgA memory B-cell|IgA memory B-lymphocyte|memory IgA B-cell|memory IgA B-lymphocyte A class switched memory B cell that expresses IgA. GO:0040039 inductive cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0040039 Migration of a cell in a multicellular organism that, having changed its location, is required to induce normal properties in one or more cells at its new location. An example of this would be the distal tip cells of Caenorhabditis elegans. CHEBI:17612 (3,4-dihydroxyphenyl)acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17612 CHEBI:17610 3-nitroacrylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17610 CL:0000949 IgD plasmablast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000949 A plasmablast that secretes IgD, and which occur in a small proportion of B cells in the adult. CL:0000941 thymic conventional dendritic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000941 A dendritic cell arising in thymus that has the phenotype CD11c-positive, CD11b-negative, and CD45RA-negative. CL:0000942 thymic plasmacytoid dendritic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000942 A plasmacytoid dendritic cell developing in the thymus with phenotype CD11c-negative or low, CD45RA-positive, CD11b-negative, and CD123-positive. CL:0000943 Be1 Cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000943 B effector cell type 1|B effector 1 cell A Be cell that facilitates development of T-helper 1 (Th1) phenotype in CD4-positive T cells, and secretes high levels of interleukin-2, tumor necrosis factor-alpha and interferon-gamma. CL:0000944 Be2 cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000944 B effector cell type 2|B effector 2 cell A Be cell that facilitates development of T-helper 2 (Th2) phenotype T cells, and secretes high levels of interleukin-2, interleukin-10, interleukin-4, and interleukin-6. RO:0002630 directly negatively regulates biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002630 RO:0002630 Process(P1) directly negatively regulates process(P2) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P1 directly negatively regulates P2. CL:0000945 lymphocyte of B lineage biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000945 A lymphocyte of B lineage with the commitment to express an immunoglobulin complex. GO:0040040 thermosensory behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0040040 thermosensory behaviour|behavioral response to temperature stimulus|behavioural response to temperature stimulus Behavior that is dependent upon the sensation of temperature. CL:0000946 antibody secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000946 A lymphocyte of B lineage that is devoted to secreting large amounts of immunoglobulin. CL:0000947 IgE plasma cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000947 A long lived plasma cell that secretes IgE. CL:0000948 IgE memory B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000948 memory IgE B cell|memory IgE B lymphocyte|IgE memory B-cell|IgE memory B-lymphocyte|memory IgE B-cell|IgE memory B lymphocyte|memory IgE B-lymphocyte A class switched memory B cell that expresses IgE on the cell surface. CHEBI:17648 N-adenylyl-L-phenylalanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17648 CHEBI:17649 hydroxymalonate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17649 CHEBI:17646 mevaldic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17646 CHEBI:17647 2-dehydro-3-deoxy-L-arabinonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17647 CL:0000940 mucosal invariant T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000940 mucosal invariant T-cell|mucosal invariant T-lymphocyte|mucosal invariant T lymphocyte An alpha-beta T cell that is found in the lamina propria of mucosal tissues and is restricted by the MR-1 molecule. CHEBI:17645 4-acetamidobutanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17645 CHEBI:17642 pentachlorophenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17642 CHEBI:17643 9-riburonosylhypoxanthine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17643 CHEBI:17640 3-(indol-3-yl)pyruvate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17640 RO:0002629 directly positively regulates biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002629 RO:0002629 Process(P1) directly postively regulates process(P2) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P1 directly positively regulates P2. CL:0000952 preBCR-positive large pre-B-II cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000952 An preBRC-positive large pre-B-II cell is a large pre-B-II cell that is pre-B cell receptor-positive, composed of surrogate light chain protein (SL), which is composed of VpreB , Lambda 5/14.1, in complex with immunoglobulin mu heavy chain (IgHmu) on the cell surface. CL:0000953 preBCR-negative large pre-B-II cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000953 A pre-BCR-negative large pre-B-II cell is a large pre-B-II cell that is pre-B cell receptor-negative, composed of surrogate light chain protein (SL), which is composed of VpreB and Lambda 5/14.1, in complex with immunoglobulin mu heavy chain (IgHmu), on the cell surface, and lack a DNA rearrangement of immunoglobulin light chain genes. CL:0000954 small pre-B-II cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000954 small pre-BII cell A small pre-B-II cell is a pre-B-II cell that is Rag1-positive, Rag2-positive, pre-BCR-negative, and BCR-negative, is not proliferating, and carries a DNA rearrangement of one or more immunoglobulin light chain genes. CL:0000955 pre-B-II cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000955 pre-B-lymphocyte|pre-BII cell A pre-B-II cell is a precursor B cell that expresses immunoglobulin mu heavy chain (IgHmu+), and lack expression of CD34, TdT, immunoglobulin kappa light chain and immunoglobulin lambda light chain. CL:0000956 pre-B-I cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000956 pre-BI cell|pro-B cell (Philadelphia nomenclature) A pre-B-I cell is a precursor B cell that expresses CD34 and surrogate immunoglobulin light chain (VpreB , Lambda 5 (mouse)/14.1 (human)) on the cell surface, and TdT, Rag1,and Rag2 intracellularly. Cell type carries a D-JH DNA rearrangement, and lacks expression of immunglobulin heavy chain protein. CL:0000957 large pre-B-II cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000957 large pre-B cell|large pre-BII cell A large pre-B-II cell is a pre-B-II cell that is proliferating and is Rag1-negative and Rag2-negative. CL:0000958 T1 B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000958 T1 B lymphocyte|transitional stage 1 B cell|T1 B-cell|T1 B-lymphocyte A transitional stage B cell that migrates from the bone marrow into the peripheral circulation, and finally to the spleen. This cell type has the phenotype surface IgM-positive, surface IgD-negative, CD21-negative, CD23-negative, and CD62L-negative, and CD93-positive. This cell type has also been described as IgM-high, CD19-positive, B220-positive, AA4-positive, and CD23-negative. CL:0000959 T2 B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000959 T2 B-lymphocyte|T2 B lymphocyte|transitional stage 2 B cell|T2 B-cell A transitional stage B cell that has the phenotype surface IgM-positive, surface IgD-postive, CD21-positive, CD23-positive, CD62L-negative, CD93-positive and is located in the splenic B follicles. This cell type has also been described as IgM-high, CD19-positive, B220-positive, AA4-positive, and CD23-positive. CHEBI:17639 3-oxo-5beta-cholanic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17639 CHEBI:17637 6-methylsalicylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17637 CHEBI:17636 sphingomyelin d18:1 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17636 CHEBI:17633 guanosine 3',5'-bis(diphosphate) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17633 CL:0000950 IgE plasmablast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000950 A plasmablast that secretes IgE. CL:0000951 IgE short lived plasma cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000951 A short lived plasma cell that secretes IgE. CHEBI:17634 D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17634 CHEBI:17631 alpha-D-Manp-(1->3)-alpha-D-Manp-(1->2)-alpha-D-Manp-(1->2)-D-Manp biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17631 CHEBI:17632 nitrate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17632 CHEBI:17630 kanamycin A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17630 GO:0005615 extracellular space biolink:CellularComponent go-plus goslim_drosophila|goslim_generic|goslim_chembl http://purl.obolibrary.org/obo/GO_0005615 NIF_Subcellular:sao1425028079 intercellular space That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. GO:0005616 larval serum protein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005616 A multisubunit protein complex which, in Drosophila, is a heterohexamer of three subunits, alpha, beta and gamma. The complex is thought to store amino acids for synthesis of adult proteins. GO:0005613 obsolete laminin receptor protein biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005613 laminin receptor protein OBSOLETE. (Was not defined before being made obsolete). GO:0005614 interstitial matrix biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005614 A type of extracellular matrix found in interstitial connective tissue, characterized by the presence of fibronectins, proteoglycans, and types I, III, V, VI, VII and XII collagens. GO:0005611 laminin-6 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005611 laminin-311 complex|laminin-6A complex A laminin complex composed of alpha3, beta1 and gamma1 polypeptide chains. GO:0005612 laminin-7 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005612 laminin-7A|laminin-321 complex A laminin complex composed of alpha3, beta2 and gamma1 polypeptide chains. GO:0005610 laminin-5 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005610 laminin-3A32 complex|laminin-5A complex|laminin-332 complex A laminin complex composed of alpha3, beta3 and gamma2 polypeptide chains. GO:0005619 ascospore wall biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005619 fungal-type spore wall The specialized cell wall of the ascospore (spore), which is the product of meiotic division. Examples of this component are found in Fungi. GO:0005617 obsolete larval serum protein-1 biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005617 LSP1|larval serum protein-1 OBSOLETE. (Was not defined before being made obsolete). GO:0005618 cell wall biolink:CellularComponent go-plus goslim_chembl|goslim_candida|goslim_yeast|goslim_pir|goslim_plant|goslim_aspergillus|goslim_metagenomics|goslim_generic http://purl.obolibrary.org/obo/GO_0005618 Wikipedia:Cell_wall The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins. GO:0005626 obsolete insoluble fraction biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005626 particle-bound|insoluble fraction OBSOLETE. That fraction of cells, prepared by disruptive biochemical methods, that is not soluble in water. GO:0005627 obsolete ascus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005627 ascus OBSOLETE. A sac-like fruiting body (ascomycete Fungi); contains ascospores (typically eight in number). GO:0005624 obsolete membrane fraction biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005624 membrane fraction OBSOLETE. That fraction of cells, prepared by disruptive biochemical methods, that includes the plasma and other membranes. GO:0005625 obsolete soluble fraction biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005625 soluble fraction|soluble OBSOLETE. That fraction of cells, prepared by disruptive biochemical methods, that is soluble in water. GO:0005622 intracellular anatomical structure biolink:CellularComponent go-plus goslim_generic|goslim_chembl|gocheck_do_not_annotate|goslim_plant|goslim_metagenomics http://purl.obolibrary.org/obo/GO_0005622 Wikipedia:Intracellular protoplasm|protoplast|nucleocytoplasm|intracellular|internal to cell A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm. PR:000018934 aryl hydrocarbon receptor proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000018934 AHR/ClvPrd An aryl hydrocarbon receptor that has been processed by proteolytic cleavage. GO:0005623 obsolete cell biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005623 Wikipedia:Cell_(biology)|NIF_Subcellular:sao1813327414 OBSOLETE. The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. GO:0005620 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005620 GO:0005621 cellular bud scar biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005621 Crater-like ring of chitinous scar tissue located on the surface of the mother cell. It is formed after the newly emerged daughter cell separates thereby marking the site of cytokinesis and septation. The number of bud scars that accumulate on the surface of a cell is a useful determinant of replicative age. CHEBI:42589 beta-L-fucose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_42589 GO:0005628 prospore membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005628 FSM|ascospore-type prospore membrane|forespore membrane The prospore membrane is a double-membraned structure that extends from the cytoplasmic face of the spindle pole bodies to encompass the spindle pole bodies and the four nuclear lobes that are formed during meiosis. It helps isolate the meiotic nuclei from the cytoplasm during spore formation and serves as a foundation for the formation of the spore walls. An example of this component is found in Schizosaccharomyces pombe. GO:0005604 basement membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005604 Wikipedia:Basement_membrane basal lamina|lamina densa|basement lamina A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers. GO:0005605 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005605 GO:0005602 complement component C1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005602 complement component C1q complex A protein complex composed of six subunits of C1q, each formed of the three homologous polypeptide chains C1QA, C1QB, and C1QB, and tetramer of two C1QR and two C1QS polypeptide chains. GO:0005603 obsolete complement component C2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005603 complement component C2 complex OBSOLETE. (Was not defined before being made obsolete). GO:0005600 collagen type XIII trimer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005600 A collagen homotrimer of alpha1(XIII) chains; type XIII collagen triple helices span the plasma membrane. GO:0005601 classical-complement-pathway C3/C5 convertase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005601 A heterodimeric protein complex that catalyzes the cleavage of complement components C3 and C5, and acts in the classical pathway of complement activation; consists of one monomer of C2a and one monomer of C4b; C2a is the catalytic subunit, but cannot catalyze cleavage alone. CHEBI:42564 alpha-D-fucose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_42564 GO:0005608 laminin-3 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005608 laminin-121 complex A laminin complex composed of alpha1, beta2 and gamma1 polypeptide chains. GO:0005609 laminin-4 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005609 laminin-221 complex A laminin complex composed of alpha2, beta2 and gamma1 polypeptide chains. GO:0005606 laminin-1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005606 laminin-111 complex A laminin complex composed of alpha1, beta1 and gamma1 polypeptide chains. GO:0005607 laminin-2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005607 laminin-211 complex A laminin complex composed of alpha2, beta1 and gamma1 polypeptide chains. CHEBI:17590 octane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17590 CHEBI:17589 3-chloro-cis,cis-muconate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17589 CHEBI:17587 L-gulono-1,4-lactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17587 CHEBI:17588 L-homocysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17588 CHEBI:17585 trans-hexadec-2-enal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17585 CHEBI:17586 CoA-glutathione biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17586 CHEBI:17583 N-(long-chain-fatty-acyl)-L-glutamate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17583 CHEBI:17581 N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17581 CHEBI:17582 isochorismic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17582 CHEBI:17580 linalool biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17580 CHEBI:42548 alpha-L-fucose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_42548 CHEBI:17578 toluene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17578 CHEBI:17579 beta-carotene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17579 CHEBI:17576 (3R)-3-hydroxy-L-aspartic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17576 CHEBI:17574 biochanin A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17574 CHEBI:17575 S-(5-deoxy-D-ribos-5-yl)-L-homocysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17575 CHEBI:17572 5-amino-2-oxopentanoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17572 CHEBI:17573 glycyrrhetinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17573 CHEBI:17571 beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17571 CHEBI:42539 (R)-3-hydroxytetradecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_42539 CHEBI:42534 epitestosterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_42534 CHEBI:545687 traumatic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_545687 RO:0012003 acts on population of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0012003 RO:0012003 p acts on population of c iff c' is a collection, has members of type c, and p has participant c NCBITaxon:197562 Pancrustacea organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_197562 NCBITaxon:197563 Mandibulata organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_197563 mandibulates CHEBI:569624 papulacandin B biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_569624 CHEBI:17598 phorbol 12,13-dibutanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17598 CHEBI:17596 inosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17596 CHEBI:17597 4-hydroxybenzaldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17597 CHEBI:17594 hydroquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17594 CHEBI:17592 N(5)-methyl-L-glutamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17592 CHEBI:17593 maltooligosaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17593 GO:0030659 cytoplasmic vesicle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030659 The lipid bilayer surrounding a cytoplasmic vesicle. GO:0030657 obsolete regulation of coenzyme and prosthetic group metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030657 regulation of coenzyme and prosthetic group metabolic process OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving coenzymes and prosthetic groups. GO:0030658 transport vesicle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030658 secretory vesicle membrane|constitutive secretory pathway transport vesicle membrane The lipid bilayer surrounding a transport vesicle. GO:0005699 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005699 GO:0030655 beta-lactam antibiotic catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030655 beta-lactam antibiotic degradation|beta-lactam antibiotic breakdown|beta-lactam antibiotic catabolism The chemical reactions and pathways resulting in the breakdown of a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins. GO:0030656 regulation of vitamin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030656 regulation of vitamin metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. GO:0005697 telomerase holoenzyme complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0005697 Telomerase is a ribonucleoprotein enzyme complex, with a minimal catalytic core composed of a catalytic reverse transcriptase subunit and an RNA subunit that provides the template for telomeric DNA addition. In vivo, the holoenzyme complex often contains additional subunits. GO:0030653 beta-lactam antibiotic metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030653 beta-lactam antibiotic metabolism The chemical reactions and pathways involving a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins. GO:0005698 obsolete centromere biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005698 centromere OBSOLETE. The region of a eukaryotic chromosome that is attached to the spindle during nuclear division. It is defined genetically as the region of the chromosome that always segregates at the first division of meiosis; the region of the chromosome in which no crossing over occurs. At the start of M phase, each chromosome consists of two sister chromatids with a constriction at a point which forms the centromere. During late prophase two kinetochores assemble on each centromere, one kinetochore on each sister chromatid. GO:0030654 beta-lactam antibiotic biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030654 beta-lactam antibiotic synthesis|beta-lactam antibiotic formation|beta-lactam antibiotic biosynthesis|beta-lactam antibiotic anabolism The chemical reactions and pathways resulting in the formation of a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins. GO:0005695 obsolete chromatid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005695 chromatid OBSOLETE. One of the two daughter strands of a duplicated chromosome that become apparent between early prophase and metaphase in mitosis and between diplotene and second metaphase in meiosis. GO:0005696 obsolete telomere biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005696 telomere OBSOLETE. A complex of DNA and protein that seals the end of a chromosome. The telomeric DNA consists of simple tandemly repeated sequences specific for each species. Typically one strand is G-rich and the other C-rich. The G-rich strand forms a 3'-terminal overhang, the length of which varies with species. The single strand overhang is bound by a variety of proteins, including telomere capping proteins that bind to the single-stranded DNA. GO:0005693 U12 snRNP biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005693 snRNP U12 A ribonucleoprotein complex that contains small nuclear RNA U12, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U12 snRNP, most of which remain associated with the U12 snRNA both while the U12 snRNP is free or assembled into a series of spliceosomal complexes. GO:0005694 chromosome biolink:CellularComponent go-plus goslim_metagenomics|goslim_generic|goslim_flybase_ribbon|goslim_chembl|goslim_candida|goslim_agr|goslim_yeast|goslim_pir|goslim_drosophila|goslim_aspergillus http://purl.obolibrary.org/obo/GO_0005694 Wikipedia:Chromosome interphase chromosome|chromatid|prophase chromosome A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. GO:0005691 U6atac snRNP biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005691 snRNP U6atac A ribonucleoprotein complex that contains small nuclear RNA U6atac, the Lsm2-8 heptameric ring complex, as well as several proteins that are unique to the U6atac snRNP, most of which remain associated with the U6atac snRNA both while the U6atac snRNP is free or assembled into the U4atac/U6atac snRNP or into a series of spliceosomal complexes. GO:0005692 U11 snRNP biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005692 snRNP U11|12S U11 snRNP A ribonucleoprotein complex that contains small nuclear RNA U11, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U11 snRNP, most of which remain associated with the U11 snRNA both while the U11 snRNP is free or assembled into a series of spliceosomal complexes. GO:0005690 U4atac snRNP biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005690 snRNP U4atac A ribonucleoprotein complex that contains small nuclear RNA U4atac, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U4atac snRNP, most of which remain associated with the U4atac snRNA both while the U4atac snRNP is free or assembled into the U4atac/U6atac complex or into a series of spliceosomal complexes. GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015018 Reactome:R-HSA-1889955|Reactome:R-HSA-3560802|MetaCyc:2.4.1.135-RXN|RHEA:24168|EC:2.4.1.135|Reactome:R-HSA-9638064 glucuronosyltransferase I activity|uridine diphosphate glucuronic acid:acceptor glucuronosyltransferase activity|UDPglucuronate:3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosyl-protein D-glucuronosyltransferase activity|UDP-glucuronate:3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosyl-protein D-glucuronosyltransferase activity Catalysis of the reaction: UDP-glucuronate + 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein = UDP + 3-beta-D-glucuronosyl-3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein. GO:0015019 heparan-alpha-glucosaminide N-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015019 EC:2.3.1.78|Reactome:R-HSA-1678660|RHEA:15125|MetaCyc:2.3.1.78-RXN|Reactome:R-HSA-2263492|Reactome:R-HSA-2090085|Reactome:R-HSA-9036056 heparin-alpha-glucosaminide N-acetyltransferase activity|acetyl-CoA:heparan-alpha-D-glucosaminide N-acetyltransferase activity|acetyl-CoA:alpha-glucosaminide N-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + heparan alpha-D-glucosaminide = CoA + heparan N-acetyl-alpha-D-glucosaminide. GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015014 heparan sulfate proteoglycan anabolism, polysaccharide chain anabolism|heparan sulfate proteoglycan formation, polysaccharide chain biosynthesis|heparan sulfate proteoglycan synthesis, polysaccharide chain synthesis|heparan sulphate proteoglycan biosynthesis, polysaccharide chain biosynthesis|heparan sulphate proteoglycan biosynthesis, polysaccharide chain biosynthetic process|heparan sulfate proteoglycan chain elongation|heparan sulfate proteoglycan formation, polysaccharide chain formation|heparin proteoglycan biosynthetic process, polysaccharide chain biosynthetic process The chemical reactions and pathways resulting in the formation of polysaccharide chain component of heparan sulfate proteoglycan. GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015015 heparan sulfate proteoglycan formation, enzymatic modification|heparin proteoglycan biosynthetic process, enzymatic modification|heparan sulphate proteoglycan biosynthesis, enzymatic modification|heparan sulfate proteoglycan anabolism, enzymatic modification|heparan sulphate proteoglycan biosynthetic process, enzymatic modification|heparan sulfate proteoglycan synthesis, enzymatic modification The modification, often by sulfation, of sugars incorporated into heparan sulfate after polymerization. GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015016 EC:2.8.2.8|RHEA:21980|Reactome:R-HSA-2022860|MetaCyc:HEPARITIN-SULFOTRANSFERASE-RXN PAPS:N-desulfoheparin sulfotransferase activity|glucosaminyl N-deacetylase/N-sulfotransferase activity|heparin-glucosamine N-sulfotransferase activity|desulfoheparin sulfotransferase activity|3'-phosphoadenylyl-sulfate:heparitin N-sulfotransferase activity|N-desulfoheparin sulfotransferase activity|heparitin N-sulfotransferase activity|heparitin sulfotransferase activity|3'-phosphoadenylyl-sulfate:N-desulfoheparin N-sulfotransferase activity|PAPS:DSH sulfotransferase activity|3'-phosphoadenylylsulfate:N-desulfoheparin sulfotransferase activity|heparan sulfate 2-N-sulfotransferase activity|heparin N-deacetylase/N-sulphotransferase activity|heparin N-sulfotransferase activity|N-HSST activity|heparan sulfate N-deacetylase/N-sulfotransferase activity|heparan sulfate N-sulfotransferase activity|N-heparan sulfate sulfotransferase activity|[heparan sulphate]-glucosamine N-sulphotransferase activity|heparitin N-sulphotransferase activity|heparin N-deacetylase/N-sulfotransferase activity|3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine N-sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-N-sulfoglucosamine. GO:0015017 obsolete glypican biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015017 glypican OBSOLETE. (Was not defined before being made obsolete). GO:0030651 peptide antibiotic biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030651 peptide antibiotic synthesis|peptide antibiotic formation|peptide antibiotic biosynthesis|peptide antibiotic anabolism The chemical reactions and pathways resulting in the formation of peptides with antibiotic activity. GO:0015010 tetrahydrocorphin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015010 tetrahydrocorphin metabolism The chemical reactions and pathways involving tetrahydrocorphins, tetrapyrroles that combine the structural elements of both porphyrins and corrins. GO:0015011 nickel-tetrapyrrole coenzyme metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015011 nickel-tetrapyrrole coenzyme metabolism|coenzyme F430 metabolic process The chemical reactions and pathways involving an enzyme cofactor consisting of a tetrapyrrole structure containing nickel, such as the F-430 cofactor found in methyl-coenzyme M reductase. GO:0030652 peptide antibiotic catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030652 peptide antibiotic degradation|peptide antibiotic catabolism|peptide antibiotic breakdown The chemical reactions and pathways resulting in the breakdown of peptides with antibiotic activity. CHEBI:134140 2-acylglycerol 18:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134140 GO:0015012 heparan sulfate proteoglycan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015012 RESID:AA0210 heparan sulfate proteoglycan biosynthesis|heparin proteoglycan biosynthetic process|heparan sulfate proteoglycan anabolism|heparan sulphate proteoglycan biosynthetic process|heparan sulphate proteoglycan biosynthesis|heparan sulfate proteoglycan synthesis|heparan sulfate proteoglycan formation The chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues; the former are a mixture of sulfated and nonsulfated D-glucuronic acid and L-iduronic acid; the L-iduronic acid is either sulfated or acetylated on its amino group as well as being sulfated on one of its hydroxyl groups; heparan sulfate chains are covalently linked to peptidyl-serine by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylosyl to serine residues. GO:0015013 heparan sulfate proteoglycan biosynthetic process, linkage to polypeptide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015013 heparin proteoglycan biosynthetic process, linkage to polypeptide|heparan sulphate proteoglycan biosynthetic process, linkage to polypeptide|heparan sulfate proteoglycan anabolism, linkage to polypeptide|heparan sulphate proteoglycan biosynthesis, linkage to polypeptide|heparan sulfate proteoglycan synthesis, linkage to polypeptide|heparan sulfate proteoglycan formation, linkage to polypeptide The polymerization of one or more heparan sulfate chains via a xylose link onto serine residues in the core protein of a proteoglycan. GO:0030650 peptide antibiotic metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030650 peptide antibiotic metabolism The chemical reactions and pathways involving peptides with antibiotic activity. CHEBI:134144 2-acylglycerol 20:4 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134144 CHEBI:134141 2-acylglycerol 18:1 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134141 CHEBI:134142 2-acylglycerol 18:2 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134142 GO:0030648 aminoglycoside antibiotic biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030648 aminoglycoside antibiotic formation|aminoglycoside antibiotic biosynthesis|aminoglycoside antibiotic anabolism|aminoglycoside antibiotic synthesis The chemical reactions and pathways resulting in the formation of an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin. GO:0030649 aminoglycoside antibiotic catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030649 aminoglycoside antibiotic catabolism|aminoglycoside antibiotic degradation|aminoglycoside antibiotic breakdown The chemical reactions and pathways resulting in the breakdown of an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin. GO:0030646 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030646 GO:0030647 aminoglycoside antibiotic metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030647 aminoglycoside antibiotic metabolism The chemical reactions and pathways involving an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin. GO:0030644 cellular chloride ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030644 Any process involved in the maintenance of an internal steady state of chloride ions at the level of a cell. GO:0030645 glucose catabolic process to butyrate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030645 glucose fermentation to butyrate|butyrate fermentation The anaerobic chemical reactions and pathways resulting in the breakdown of glucose, with the production of acetic acid, butyric acid, carbon dioxide (CO2), and dihydrogen; effected by some saccharolytic species of Clostridium, e.g. C. butyricum. GO:0030642 cellular sulfate ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030642 sulphate ion homeostasis Any process involved in the maintenance of an internal steady state of sulfate ions at the level of a cell. GO:0030643 cellular phosphate ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030643 Any process involved in the maintenance of an internal steady state of phosphate ions at the level of a cell. GO:0015029 obsolete internalization receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015029 internalization receptor activity OBSOLETE. (Was not defined before being made obsolete). CHEBI:134158 N-acylethanolamine 18:1 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134158 CHEBI:134159 N-acylethanolamine 18:2 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134159 CHEBI:134156 N-acylethanolamine 16:1 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134156 CHEBI:134157 N-acylethanolamine 18:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134157 GO:0015025 obsolete GPI-anchored membrane-bound receptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015025 GPI-anchored membrane-bound receptor OBSOLETE. (Was not defined before being made obsolete). GO:0015026 coreceptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015026 coreceptor, soluble ligand activity|coreceptor, insoluble ligand activity Combining with an extracellular or intracellular messenger, and in cooperation with a nearby primary receptor, initiating a change in cell activity. GO:0015027 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015027 GO:0015028 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015028 GO:0030640 polyketide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030640 polyketide breakdown|polyketide catabolism|polyketide degradation The chemical reactions and pathways resulting in the breakdown of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps. GO:0015021 heparin-sulfate lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015021 MetaCyc:4.2.2.8-RXN|EC:4.2.2.8 heparin-sulfate eliminase activity|heparin-sulphate lyase activity|heparitin-sulfate lyase activity|heparitinase I|[heparan sulfate]-sulfate lyase activity|heparitinase II Catalysis of the elimination of sulfate; appears to act on linkages between N-acetyl-D-glucosamine and uronate. Product is an unsaturated sugar. CHEBI:134150 N-acylglycine 16:1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134150 GO:0030641 regulation of cellular pH biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030641 cellular hydrogen ion homeostasis|proton homeostasis Any process involved in the maintenance of an internal equilibrium of hydrogen ions (protons) within a cell or between a cell and its external environment. GO:0015022 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015022 CHEBI:134151 N-acylglycine 18:0 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134151 GO:0015023 obsolete syndecan biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015023 syndecan OBSOLETE. (Was not defined before being made obsolete). GO:0015024 glucuronate-2-sulfatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015024 EC:3.1.6.18|MetaCyc:3.1.6.18-RXN chondro-2-sulfatase activity|polysaccharide-2-O-sulfo-D-glucuronate 2-sulfohydrolase activity|glucurono-2-sulfatase activity|glucuronate-2-sulphatase activity Catalysis of the hydrolysis of the 2-sulfate groups of the 2-O-sulfo-D-glucuronate residues of chondroitin sulfate, heparin and heparitin sulfate. CHEBI:134152 N-acylglycine 18:1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134152 GO:0015020 glucuronosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015020 Reactome:R-HSA-159194|MetaCyc:UDP-GLUCURONOSYLTRANSFERASE-RXN|Reactome:R-HSA-9632039|Reactome:R-HSA-9036102|Reactome:R-HSA-9036104|Reactome:R-HSA-5617143|Reactome:R-HSA-8941701|EC:2.4.1.17|Reactome:R-HSA-9638097|Reactome:R-HSA-2162099|Reactome:R-HSA-9632038|Reactome:R-HSA-174931|Reactome:R-HSA-174916|Reactome:R-HSA-5604975|Reactome:R-HSA-5604954|Reactome:R-HSA-159179|RHEA:21032 UDP-glucuronate-bilirubin glucuronyltransferase activity|UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|UDP glucuronyltransferase activity|p-nitrophenol UDP-glucuronyltransferase activity|uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|3-OH androgenic UDPGT activity|uridine diphosphate glucuronyltransferase activity|ciramadol UDP-glucuronyltransferase activity|uridine diphosphoglucuronyltransferase activity|pnp-UDPGT activity|UDP glucuronate-estriol glucuronosyltransferase activity|uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|p-phenylphenol glucuronyltransferase activity|4-nitrophenol UDP-glucuronyltransferase activity|p-nitrophenylglucuronosyltransferase activity|p-hydroxybiphenyl UDP glucuronyltransferase activity|bilirubin UDP-glucuronosyltransferase activity|17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|GT activity|17beta-hydroxysteroid UDP-glucuronosyltransferase activity|UDPGT activity|uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|uridine 5'-diphosphoglucuronyltransferase activity|phenyl-UDP-glucuronosyltransferase activity|morphine glucuronyltransferase activity|1-naphthol glucuronyltransferase activity|UDPGA-glucuronyltransferase activity|UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|bilirubin monoglucuronide glucuronyltransferase activity|4-methylumbelliferone UDP-glucuronosyltransferase activity|UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|UDP-glucuronosyltransferase activity|uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|1-naphthol-UDP-glucuronosyltransferase activity|3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|UDP glucuronate-estradiol-glucuronosyltransferase activity|UDP-glucuronyltransferase activity|bilirubin glucuronyltransferase activity|PNP-UDPGT|estriol UDPglucuronosyltransferase activity|UDP glucuronic acid transferase activity|estrone UDPglucuronosyltransferase activity|bilirubin uridine diphosphoglucuronyltransferase activity|4-nitrophenol UDPGT activity|4-hydroxybiphenyl UDP-glucuronosyltransferase activity|3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|17-OH steroid UDPGT activity|p-nitrophenol UDP-glucuronosyltransferase activity|uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|UDPGA transferase activity|UDP glucuronosyltransferase activity|bilirubin UDPGT activity|uridine diphosphoglucuronosyltransferase activity Catalysis of the reaction: UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside. GO:0030637 obsolete acetate derivative catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030637 acetate derivative degradation|acetate derivative catabolism|acetate derivative breakdown|acetate derivative catabolic process OBSOLETE. The chemical reactions and pathways resulting in the breakdown of derivatives of acetic acid. GO:0030638 polyketide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030638 polyketide metabolism The chemical reactions and pathways involving polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps. GO:0030635 obsolete acetate derivative metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030635 acetate derivative metabolic process|acetate derivative metabolism OBSOLETE. The chemical reactions and pathways involving derivatives of acetic acid. GO:0005679 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005679 GO:0030636 obsolete acetate derivative biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030636 acetate derivative biosynthetic process|acetate derivative biosynthesis|acetate derivative anabolism|acetate derivative synthesis|acetate derivative formation OBSOLETE. The chemical reactions and pathways resulting in the formation of derivatives of acetic acid. GO:0030633 D-alanine family amino acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030633 D-alanine family amino acid degradation|D-alanine family amino acid breakdown|D-alanine family amino acid catabolism The chemical reactions and pathways resulting in the breakdown of D-alanine and related amino acids. GO:0005677 chromatin silencing complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005677 Any protein complex that mediates changes in chromatin structure that result in transcriptional silencing. GO:0005678 obsolete chromatin assembly complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005678 chromatin assembly complex|nucleosome assembly complex OBSOLETE. Any protein complex that acts in the formation of nucleosomes or higher order chromatin structure. GO:0030634 carbon fixation by acetyl-CoA pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030634 MetaCyc:CODH-PWY|Wikipedia:Wood-Ljungdahl_pathway acetyl CoA pathway|reductive acetyl CoA pathway|Ljungdahl-Wood pathway A pathway of carbon dioxide fixation in which one molecule of acetyl-CoA is completely synthesized from two molecules of carbon dioxide (CO2). GO:0005675 transcription factor TFIIH holo complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005675 holo TFIIH complex A complex that is capable of kinase activity directed towards the C-terminal Domain (CTD) of the largest subunit of RNA polymerase II and is essential for initiation at RNA polymerase II promoters in vitro. It is composed of the core TFIIH complex and the TFIIK complex. GO:0030631 pyrrolysine incorporation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030631 RESID:AA0321 monomethylamine methyltransferase cofactor lysine adduct incorporation|lysine methylamine methyltransferase cofactor adduct incorporation The incorporation of pyrrolysine, also known as lysine methylamine methyltransferase cofactor adduct, into a peptide; uses a special tRNA that recognizes the UAG codon as a modified lysine, rather than as a termination codon. Pyrrolysine may be synthesized as a free amino acid or synthesized from a lysine charged tRNA before its incorporation; it is not a posttranslational modification of peptidyl-lysine; this modification is found in several Methanosarcina methylamine methyltransferases. GO:0030632 D-alanine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030632 D-alanine formation|D-alanine biosynthesis|D-alanine anabolism|D-alanine synthesis The chemical reactions and pathways resulting in the formation of D-alanine, the D-enantiomer of the amino acid alanine, i.e (2R)-2-aminopropanoic acid. GO:0005676 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005676 GO:0005673 transcription factor TFIIE complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005673 A transcription factor which in humans consists of a complex of two alpha and two beta chains. Recruits TFIIH to the initiation complex and helps activate both RNA polymerase II and TFIIH. GO:0005674 transcription factor TFIIF complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005674 A general transcription initiation factor which in humans consists of a heterodimer of an alpha and a beta subunit. Helps recruit RNA polymerase II to the initiation complex and promotes translation elongation. GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005671 ATAC complex|Ada-Two-A-containing complex|Ada Two-A containing complex A multiprotein complex that possesses histone acetyltransferase and is involved in regulation of transcription. Contains either GCN5 or PCAF in a mutually exclusive manner. The budding yeast complex includes Gcn5p, two proteins of the Ada family, and two TBP-associate proteins (TAFs); analogous complexes in other species have analogous compositions, and usually contain homologs of the yeast proteins. Both ATAC- or SAGA (see GO:0000124, SAGA complex) are involved in the acetylation of histone H3K9 and K14 residues. GO:0005672 transcription factor TFIIA complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005672 A component of the transcription machinery of RNA Polymerase II. In humans, TFIIA is a heterotrimer composed of an alpha (P35), beta (P19) and gamma subunits (P12). GO:0005670 obsolete transcription-activating factor, 30kD biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005670 transcription-activating factor, 30kD OBSOLETE. (Was not defined before being made obsolete). GO:0030639 polyketide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030639 polyketide anabolism|polyketide synthesis|polyketide biosynthesis|polyketide formation The chemical reactions and pathways resulting in the formation of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps. CHEBI:134125 (R)-NADHX biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134125 CHEBI:134129 1-acylglycerol 18:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134129 CHEBI:134127 1-acylglycerol 16:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134127 GO:0030630 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030630 CHEBI:134121 N-oleoyl-L-isoleucinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134121 CHEBI:134122 N-oleoyl-L-glutamate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134122 GO:0030626 U12 snRNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030626 Interacting selectively and non-covalently with the U12 small nuclear RNA (U12 snRNA). GO:0030627 pre-mRNA 5'-splice site binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030627 pre-mRNA 5' splice site binding Interacting selectively and non-covalently with the pre-mRNA 5' splice site sequence. GO:0030624 U6atac snRNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030624 Interacting selectively and non-covalently with the U6atac small nuclear RNA (U6atac snRNA). GO:0030625 U11 snRNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030625 Interacting selectively and non-covalently with the U11 small nuclear RNA (U11 snRNA). GO:0030622 U4atac snRNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030622 Interacting selectively and non-covalently with the U4atac small nuclear RNA (U4atac snRNA). GO:0005688 U6 snRNP biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005688 snRNP U6 A ribonucleoprotein complex that contains small nuclear RNA U6, the Lsm2-8 heptameric ring complex, as well as several proteins that are unique to the U6 snRNP, most of which remain associated with the U6 snRNA both while the U6 snRNP is free or assembled into the U4/U6 snRNP or into a series of spliceosomal complexes. GO:0030623 U5 snRNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030623 Interacting selectively and non-covalently with the U5 small nuclear RNA (U5 snRNA). GO:0005689 U12-type spliceosomal complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005689 Wikipedia:Minor_spliceosome minor spliceosomal complex|AT-AC spliceosomal complex|minor (U12-type) spliceosomal complex Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron; the series of U12-type spliceosomal complexes is involved in the splicing of the majority of introns that contain atypical AT-AC terminal dinucleotides, as well as other non-canonical introns. The entire splice site signal, not just the terminal dinucleotides, is involved in determining which spliceosome utilizes the site. GO:0005686 U2 snRNP biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005686 17S U2 snRNP|snRNP U2 A ribonucleoprotein complex that contains small nuclear RNA U2, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U2 snRNP, most of which remain associated with the U2 snRNA both while the U2 snRNP is free or assembled into a series of spliceosomal complexes. GO:0030620 U2 snRNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030620 Interacting selectively and non-covalently with the U2 small nuclear RNA (U2 snRNA). GO:0005687 U4 snRNP biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005687 snRNP U4 A ribonucleoprotein complex that contains small nuclear RNA U4, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U4 snRNP, most of which remain associated with the U4 snRNA both while the U4 snRNP is free or assembled into the U4/U6 snRNP or into a series of spliceosomal complexes. GO:0030621 U4 snRNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030621 Interacting selectively and non-covalently with the U4 small nuclear RNA (U4 snRNA). GO:0005684 U2-type spliceosomal complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005684 major spliceosomal complex|major (U2-type) spliceosomal complex|GT-AG spliceosome Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron that has canonical consensus sequences near the 5' and 3' ends. GO:0005685 U1 snRNP biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005685 snRNP U1 A ribonucleoprotein complex that contains small nuclear RNA U1, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U1 snRNP, most of which remain associated with the U1 snRNA both while the U1 snRNP is free or assembled into a series of spliceosomal complexes. GO:0005682 U5 snRNP biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005682 snRNP U5 A ribonucleoprotein complex that contains small nuclear RNA U5, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U5 snRNP, most of which remain associated with the U5 snRNA both while the U5 snRNP is free or assembled into a series of spliceosomal complexes. GO:0005683 U7 snRNP biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005683 snRNP U7 A ribonucleoprotein complex that contains the U7 snRNA and is required for the 3'-end processing of replication-dependent histone pre-mRNAs. GO:0005680 anaphase-promoting complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005680 Wikipedia:Anaphase-promoting_complex APC|cyclosome|anaphase promoting complex A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B. GO:0005681 spliceosomal complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0005681 Wikipedia:Spliceosome spliceosome|spliceosome complex Any of a series of ribonucleoprotein complexes that contain snRNA(s) and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the spliceosomal splicing of one or more substrate RNAs, and which also contain the RNA substrate(s) from the initial target RNAs of splicing, the splicing intermediate RNA(s), to the final RNA products. During cis-splicing, the initial target RNA is a single, contiguous RNA transcript, whether mRNA, snoRNA, etc., and the released products are a spliced RNA and an excised intron, generally as a lariat structure. During trans-splicing, there are two initial substrate RNAs, the spliced leader RNA and a pre-mRNA. GO:0030628 pre-mRNA 3'-splice site binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030628 pre-mRNA 3' splice site binding Interacting selectively and non-covalently with the pre-mRNA 3' splice site sequence. GO:0030629 U6 snRNA 3'-end binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030629 U6 snRNA 3' end binding Interacting selectively and non-covalently with the 3' end of the U6 small nuclear RNA (U6 snRNA). GO:0015007 obsolete electron carrier, chlorophyll electron transport system biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015007 chlorophyll electron carrier|electron carrier, chlorophyll electron transport system OBSOLETE. A molecular entity that serves as an electron acceptor and electron donor in a chlorophyll electron transport system. GO:0015008 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015008 GO:0015009 corrin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015009 corrin metabolism The chemical reactions and pathways involving corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule. GO:0015003 obsolete copper electron carrier biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015003 copper electron carrier OBSOLETE. A copper-containing entity that serves as an electron acceptor and electron donor in an electron transport system. GO:0015004 obsolete small blue copper electron carrier biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015004 small blue copper electron carrier OBSOLETE. (Was not defined before being made obsolete). GO:0015005 obsolete azurin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015005 azurin OBSOLETE. Brilliant blue copper-containing protein of low molecular weight found in some bacteria; thought to transfer electrons to cytochrome oxidase. This definition includes pseudoazurin. CHEBI:134138 2-acylglycerol 16:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134138 GO:0015006 obsolete plastocyanin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015006 plastocyanin OBSOLETE. A copper-containing electron carrier acting between cytochrome b(6)-f and P700 of photosystem I. GO:0015000 obsolete polyferredoxin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015000 polyferredoxin OBSOLETE. (Was not defined before being made obsolete). GO:0015001 obsolete high-potential iron-sulfur carrier biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015001 high-potential iron-sulphur carrier|HiPIP|high-potential iron-sulfur carrier OBSOLETE. (Was not defined before being made obsolete). GO:0015002 heme-copper terminal oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015002 haem-copper terminal oxidase activity Catalysis of the four-electron reduction of dioxygen (O2) to water, coupled to generation of a proton electrochemical gradient across a membrane. CHEBI:134133 1-acylglycerol 20:4 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134133 CHEBI:134130 1-acylglycerol 18:1 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134130 CHEBI:134131 1-acylglycerol 18:2 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134131 GO:0005659 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005659 GO:0030615 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030615 GO:0030616 obsolete transforming growth factor beta receptor, common-partner cytoplasmic mediator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030616 TGFbeta receptor, common-partner cytoplasmic mediator activity|common-partner SMAD protein|co-SMAD protein|TGF-beta receptor, common-partner cytoplasmic mediator activity|common mediator SMAD protein|common partner SMAD protein|common-mediator SMAD protein OBSOLETE. A TGF-beta cytoplasmic mediator that forms a complex with a phosphorylated pathway-specific mediator. The heterocomplex translocates to the nucleus to regulate transcription. GO:0030613 oxidoreductase activity, acting on phosphorus or arsenic in donors biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030613 EC:1.20.-.- oxidoreductase activity, acting on phosphorus or arsenic in donors, with other acceptors Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. GO:0005657 replication fork biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005657 Wikipedia:Replication_fork replication focus The Y-shaped region of a replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes. GO:0030614 oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030614 EC:1.20.4.- oxidoreductase activity, acting on phosphorus or arsenic in donors, with disulphide as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a disulfide. GO:0005658 alpha DNA polymerase:primase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005658 pol-prim|heterotetrameric polymerase alpha holoenzyme|primosome|DNA polymerase alpha:primase complex A complex of four polypeptides, comprising large and small DNA polymerase alpha subunits and two primase subunits, which are capable of catalyzing the synthesis of an RNA primer on the lagging strand of replicating DNA and the subsequent synthesis of a smal stretch of DNA. The smaller of the two primase subunits alone can catalyze oligoribonucleotide synthesis. GO:0005655 nucleolar ribonuclease P complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005655 nucleolar RNase P complex A ribonuclease P complex located in the nucleolus of a eukaryotic cell, where it catalyzes the 5' endonucleolytic cleavage of precursor tRNAs to yield mature tRNAs. Eukaryotic nucleolar ribonuclease P complexes generally contain a single RNA molecule that is necessary but not sufficient for catalysis, and several protein molecules. GO:0030611 arsenate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030611 Catalysis of the interconversion of arsenate and arsenite. GO:0005656 nuclear pre-replicative complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005656 pre-replicative complex|eukaryotic pre-replicative complex|pre-RC A protein-DNA complex assembled at eukaryotic DNA replication origins during late mitosis and G1, allowing the origin to become competent, or 'licensed', for replication. The complex normally includes the origin recognition complex (ORC), Cdc6, Cdt1 and the MiniChromosome Maintenance (Mcm2-7) proteins. PR:000018902 pituitary adenylate cyclase-activating polypeptide proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000018902 ADCYAP1/ClvPrd A pituitary adenylate cyclase-activating polypeptide that has been processed by proteolytic cleavage. GO:0030612 arsenate reductase (thioredoxin) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030612 MetaCyc:RXN-10737 Catalysis of the reaction: arsenate + thioredoxin = arsenite + thioredoxin disulfide. Thioredoxin disulfide is also known as oxidized thioredoxin. GO:0005653 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005653 GO:0005654 nucleoplasm biolink:CellularComponent go-plus goslim_plant|goslim_generic|goslim_chembl http://purl.obolibrary.org/obo/GO_0005654 Wikipedia:Nucleoplasm|NIF_Subcellular:sao661522542 That part of the nuclear content other than the chromosomes or the nucleolus. GO:0030610 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030610 GO:0005651 obsolete exportin biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005651 exportin OBSOLETE. (Was not defined before being made obsolete). GO:0005652 nuclear lamina biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005652 Wikipedia:Nuclear_lamina|NIF_Subcellular:sao1455996588 The fibrous, electron-dense layer lying on the nucleoplasmic side of the inner membrane of a cell nucleus, composed of lamin filaments. The polypeptides of the lamina are thought to be concerned in the dissolution of the nuclear envelope and its re-formation during mitosis. The lamina is composed of lamin A and lamin C filaments cross-linked into an orthogonal lattice, which is attached via lamin B to the inner nuclear membrane through interactions with a lamin B receptor, an IFAP, in the membrane. GO:0005650 obsolete importin, alpha-subunit transport factor biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005650 CAS|importin, alpha-subunit transport factor OBSOLETE. (Was not defined before being made obsolete). GO:0030619 U1 snRNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030619 Interacting selectively and non-covalently with the U1 small nuclear RNA (U1 snRNA). GO:0030617 obsolete transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030617 inhibitory SMAD protein|TGFbeta receptor, inhibitory cytoplasmic mediator activity|TGF-beta receptor, inhibitory cytoplasmic mediator activity OBSOLETE. A TGF-beta cytoplasmic mediator that inhibits the signaling function of common-partner and pathway-specific mediators. GO:0030618 obsolete transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030618 pathway-restricted SMAD protein|receptor-regulated SMAD protein|TGFbeta receptor, pathway-specific cytoplasmic mediator activity|pathway-specific SMAD protein|pathway restricted SMAD protein|TGF-beta receptor, pathway-specific cytoplasmic mediator activity|receptor regulated SMAD protein OBSOLETE. A TGF-beta cytoplasmic mediator that is phosphorylated by a TGFbeta receptor and complexes with a common-partner mediator. The- heterocomplex translocates to the nucleus to regulate transcription. CHEBI:134103 N-arachidonoyl-L-leucinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134103 CHEBI:134102 (R)-2-amino-4-oxopentanoic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134102 GO:0030604 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030604 EC:1.1.1.267|RHEA:13717|KEGG_REACTION:R05688|MetaCyc:DXPREDISOM-RXN DXP-reductoisomerase activity|1-deoxyxylulose-5-phosphate reductoisomerase activity|2-C-methyl-D-erythritol-4-phosphate:NADP+ oxidoreductase (isomerizing)|1-deoxy-D-xylulose-5-phosphate isomeroreductase activity|DOXP reductoisomerase activity|2C-methyl-D-erythritol-4-phosphate (MEP) synthase activity Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + NADP(+) = 1-deoxy-D-xylulose 5-phosphate + H(+) + NADPH. GO:0030605 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030605 GO:0030602 obsolete chymosin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030602 rennin (but this should be avoided since it leads to confusion with renin)|chymosin activity|rennin OBSOLETE. Catalysis of the lysis of peptide bonds with broad specificity similar to that of pepsin A. Clots milk by cleavage of a single Ser-Phe-l-Met-Ala bond in kappa-casein. GO:0005668 RNA polymerase transcription factor SL1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005668 TIF-IB|selectivity factor SL1 complex A RNA polymerase I-specific transcription factor complex that contains the TATA-box-binding protein (TBP) and at least three TBP-associated factors including proteins known in mammals as TAFI110, TAFI63 and TAFI48. GO:0005669 transcription factor TFIID complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005669 A complex composed of TATA binding protein (TBP) and TBP associated factors (TAFs); the total mass is typically about 800 kDa. Most of the TAFs are conserved across species. In TATA-containing promoters for RNA polymerase II (Pol II), TFIID is believed to recognize at least two distinct elements, the TATA element and a downstream promoter element. TFIID is also involved in recognition of TATA-less Pol II promoters. Binding of TFIID to DNA is necessary but not sufficient for transcription initiation from most RNA polymerase II promoters. GO:0030603 oxaloacetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030603 EC:3.7.1.1|MetaCyc:OXALOACETASE-RXN|KEGG_REACTION:R00338|RHEA:24432 oxalacetic hydrolase activity|oxaloacetate acetylhydrolase activity Catalysis of the reaction: H(2)O + oxaloacetate = acetate + H(+) + oxalate. GO:0030600 feruloyl esterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030600 MetaCyc:3.1.1.73-RXN|EC:3.1.1.73 FAE-I|FAE-III|FAE-II|FAEA|cinnamoyl ester hydrolase activity|4-hydroxy-3-methoxycinnamoyl-sugar hydrolase activity|hemicellulase accessory|hydroxycinnamoyl esterase activity|cinnAE|ferulic acid esterase activity Catalysis of the reaction: feruloyl-polysaccharide + H2O = ferulate + polysaccharide. GO:0005666 RNA polymerase III complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005666 DNA-directed RNA polymerase III activity|DNA-directed RNA polymerase III complex RNA polymerase III, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces 5S rRNA, tRNAs and some of the small nuclear RNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase I and others of which are also found in RNA polymerases I and II. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template. GO:0005667 transcription regulator complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0005667 transcription factor complex|nuclear transcription factor complex|cytoplasmic transcription factor complex A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription. GO:0030601 obsolete aminopeptidase B activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030601 cytosol aminopeptidase IV|Cl--activated arginine aminopeptidase activity|arginyl aminopeptidase activity|arylamidase II|aminopeptidase B activity|L-arginine aminopeptidase activity OBSOLETE. Catalysis of the release of N-terminal Arg and Lys from oligopeptides when P1' is not Pro. Also acts on arylamides of Arg and Lys. GO:0005664 nuclear origin of replication recognition complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005664 eukaryotic ORC|nuclear ORC A multisubunit complex that is located at the replication origins of a chromosome in the nucleus. GO:0005665 RNA polymerase II, core complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005665 RNA polymerase II complex|DNA-directed RNA polymerase II, core complex|RNAP II complex RNA polymerase II, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces mRNAs, snoRNAs, and some of the snRNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The largest subunit of RNA polymerase II contains an essential carboxyl-terminal domain (CTD) composed of a variable number of heptapeptide repeats (YSPTSPS). The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerases I and III. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template. GO:0005662 DNA replication factor A complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005662 Wikipedia:Replication_protein_A replication protein A|RPA A conserved heterotrimeric complex that binds nonspecifically to single-stranded DNA and is required for multiple processes in eukaryotic DNA metabolism, including DNA replication, DNA repair, and recombination. In all eukaryotic organisms examined the complex is composed of subunits of approximately 70, 30, and 14 kDa. GO:0005663 DNA replication factor C complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0005663 activator 1 complex|RFC complex A complex that loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA, thereby permitting processive DNA synthesis catalyzed by DNA polymerase. In eukaryotes the complex consists of five polypeptides. GO:0005660 obsolete delta-DNA polymerase cofactor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005660 delta DNA polymerase cofactor complex|delta-DNA polymerase cofactor complex OBSOLETE. A complex of proteins that interacts with delta-DNA polymerase, promoting elongation. In humans it is a heteropentamer of subunits of 140/145, 40, 38, 37 and 36.5 kDa, which form a complex with the proliferating cell nuclear antigen (PCNA) in the presence of ATP. GO:0005661 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005661 GO:0030608 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030608 GO:0030609 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030609 GO:0030606 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030606 GO:0030607 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030607 CHEBI:6746 menadiol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_6746 CHEBI:134119 beta-muricholate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134119 CHEBI:134116 alpha-muricholate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134116 CHEBI:134110 (9Z,11S,12Z,15Z)-11-hydroperoxyoctadecatrienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134110 GO:0005637 nuclear inner membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005637 NIF_Subcellular:sao1612527463 inner envelope|nucleus inner membrane|inner nuclear membrane The inner, i.e. lumen-facing, lipid bilayer of the nuclear envelope. GO:0005638 lamin filament biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005638 type V intermediate filament Any of a group of intermediate-filament proteins that form the fibrous matrix on the inner surface of the nuclear envelope. They are classified as lamins A, B and C. GO:0005635 nuclear envelope biolink:CellularComponent go-plus goslim_plant|goslim_generic|goslim_chembl http://purl.obolibrary.org/obo/GO_0005635 Wikipedia:Nuclear_envelope The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space). GO:0005636 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005636 GO:0005633 ascus lipid droplet biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005633 ascus lipid particle Any particle of coalesced lipids in an ascus or ascospore. May include associated proteins. GO:0005634 nucleus biolink:CellularComponent go-plus goslim_yeast|goslim_agr|goslim_candida|goslim_plant|goslim_pir|goslim_drosophila|goslim_aspergillus|goslim_metagenomics|goslim_generic|goslim_flybase_ribbon|goslim_chembl|goslim_mouse http://purl.obolibrary.org/obo/GO_0005634 NIF_Subcellular:sao1702920020|Wikipedia:Cell_nucleus horsetail nucleus|cell nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. GO:0005631 chitosan layer of spore wall biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005631 The second outermost layer of the spore wall, as described in Saccharomyces. GO:0005632 inner layer of spore wall biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005632 Either of the two innermost layers of the spore wall, as described in Saccharomyces. GO:0005630 dityrosine layer of spore wall biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005630 The outermost layer of the spore wall, as described in Saccharomyces. CHEBI:6714 (+)-medicarpin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_6714 GO:0005639 integral component of nuclear inner membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005639 integral to nuclear inner membrane The component of the nuclear inner membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0005648 obsolete importin, beta-subunit biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005648 karyopherin-beta1|importin, beta-subunit OBSOLETE. (Was not defined before being made obsolete). GO:0005649 obsolete transportin biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005649 karyopherin-beta2|transportin OBSOLETE. (Was not defined before being made obsolete). GO:0005646 obsolete importin biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005646 karyopherin|importin OBSOLETE. (Was not defined before being made obsolete). GO:0005647 obsolete importin, alpha-subunit biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005647 importin, alpha-subunit|karyopherin-alpha OBSOLETE. (Was not defined before being made obsolete). GO:0005644 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005644 GO:0005645 obsolete RAN-binding protein biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005645 RAN-binding protein OBSOLETE. (Was not defined before being made obsolete). GO:0005642 annulate lamellae biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005642 Stacks of endoplasmic reticulum (ER) membranes containing a high density of nuclear pores, thought to form from excess nuclear membrane components, that have been described in a number of different cells. Annulate lamellar membranes are continuous with and embedded within the ER. GO:0005643 nuclear pore biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0005643 NIF_Subcellular:sao220861693|Wikipedia:Nuclear_pore nuclear pore complex|nuclear pore membrane protein|nucleopore|NPC A protein complex providing a discrete opening in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined. GO:0005640 nuclear outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005640 NIF_Subcellular:sao1617136075 perinuclear membrane|nucleus outer envelope The outer, i.e. cytoplasm-facing, lipid bilayer of the nuclear envelope; continuous with the endoplasmic reticulum of the cell and sometimes studded with ribosomes. GO:0005641 nuclear envelope lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005641 nuclear intermembrane space|nuclear membrane lumen|perinuclear space The region between the two lipid bilayers of the nuclear envelope; 20-40 nm wide. CL:0000806 DN2 thymocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000806 TN2 cell|DN2 immature T cell|DN2 alpha-beta immature T-cell|TN2 thymocyte|DN2 alpha-beta immature T-lymphocyte|DN2 cell|preT.DN2.Th|double negative 2|DN2 alpha-beta immature T lymphocyte A thymocyte that has the phenotype CD4-negative, CD8-negative, CD44-positive, and CD25-positive. CL:0000807 DN3 thymocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000807 DN3 immature T cell|TN3 cell|TN3 thymocyte|DN3 alpha-beta immature T-cell|DN3 alpha-beta immature T-lymphocyte|DN3 cell|double negative 3|preT.DN3.Th|DN3 alpha-beta immature T lymphocyte|early cortical thymocyte A thymocyte that has the phenotype CD4-negative, CD8-negative, CD44-negative, and CD25-positive and expressing the T cell receptor beta-chain in complex with the pre-T cell receptor alpha chain. CL:0000808 DN4 thymocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000808 DN4 immature T cell|DN4 alpha-beta immature T-lymphocyte|DN4 immature T-cell|DN4 cell|double negative 4|DN4 alpha-beta immature T lymphocyte|early cortical thymocyte|T.DN4.th A thymocyte that has the phenotype CD4-negative, CD8-negative, CD44-negative, CD25-negative, and pre-TCR-positive. CL:0000809 double-positive, alpha-beta thymocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000809 late cortical thymocyte|double-positive, alpha-beta immature T lymphocyte|DP thymocyte|DP cell A thymocyte expressing the alpha-beta T cell receptor complex as well as both the CD4 and CD8 coreceptors. CL:0000800 mature gamma-delta T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000800 mature gamma-delta T-cell|mature gamma-delta T-lymphocyte|mature gamma-delta T lymphocyte A gamma-delta T cell that has a mature phenotype. These cells can be found in tissues and circulation where they express unique TCR repertoire depending on their location. CL:0000801 gamma-delta intraepithelial T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000801 gamma-delta intraepithelial T-lymphocyte|IEL|gamma-delta intraepithelial T lymphocyte|intraepithelial lymphocyte|gamma-delta intraepithelial T-cell A mature gamma-delta T cell that is found in the columnar epithelium of the gastrointestinal tract. These cells participate in mucosal immune responses. CL:0000802 CD8-alpha alpha positive, gamma-delta intraepithelial T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000802 IEL|CD8-positive, gamma-delta intraepithelial T lymphocyte|intraepithelial lymphocyte|CD8-positive, gamma-delta intraepithelial T-cell|CD8-positive, gamma-delta intraepithelial T-lymphocyte A gamma-delta intraepithelial T cell that has the phenotype CD8-alpha alpha-positive. CL:0000803 CD4-negative CD8-negative gamma-delta intraepithelial T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000803 CD4-positive, gamma-delta intraepithelial T lymphocyte|IEL|intraepithelial lymphocyte|CD4-positive, gamma-delta intraepithelial T-cell|CD4-positive, gamma-delta intraepithelial T-lymphocyte A gamma-delta intraepithelial T cell that has the phenotype CD4-negative and CD8-negative. CL:0000805 immature single positive thymocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000805 immature single positive T lymphocyte|ISP|immature single positive T-lymphocyte|T.ISP.th|immature single positive T cell A thymocyte that has the phenotype CD4-negative, CD8-positive, CD44-negative, CD25-negative, and pre-TCR-positive. CHEBI:6530 longifolene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_6530 CL:0000817 precursor B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000817 pre-B cell A precursor B cell is a B cell with the phenotype CD10-positive. CL:0000818 transitional stage B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000818 transitional stage B-cell|transitional stage B-lymphocyte|T1 B cell|T2 B cell|T3 B cell|transitional B cell|transitional stage B lymphocyte An immature B cell of an intermediate stage between the pre-B cell stage and the mature naive stage with the phenotype surface IgM-positive and CD19-positive, and are subject to the process of B cell selection. A transitional B cell migrates from the bone marrow into the peripheral circulation, and then to the spleen. CL:0000819 B-1 B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000819 B1 B-cell|B-1 cell|B1 B-lymphocyte|B-1 B lymphocyte|B1 cell|B1 B cell|B1 B lymphocyte|B-1 B-cell|B-1 B-lymphocyte A B cell of distinct lineage and surface marker expression. B-1 B cells are thought to be the primary source of natural IgM immunoglobulin, that is, IgM produced in large quantities without prior antigenic stimulation and generally reactive against various microorganisms, as well as the source of T-independent IgA immunoglobulin in the mucosal areas. These cells are CD43-positive. CL:0000810 CD4-positive, alpha-beta thymocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000810 CD4-positive, alpha-beta immature T-cell|SP CD4 cell|CD4-positive, alpha-beta immature T-lymphocyte|CD4-positive, alpha-beta immature T lymphocyte An immature alpha-beta T cell that is located in the thymus and is CD4-positive and CD8-negative. CL:0000811 CD8-positive, alpha-beta thymocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000811 CD8-positive, alpha-beta immature T-cell|SP CD8 cell|CD8-positive, alpha-beta immature T-lymphocyte|CD8-positive, alpha-beta immature T lymphocyte|CD8-positive, alpha-beta immature T cell An immature alpha-beta T cell that is located in the thymus and is CD8-positive and CD4-negative. CL:0000813 memory T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000813 memory T-cell|memory T-lymphocyte|memory T lymphocyte A long-lived, antigen-experienced T cell that has acquired a memory phenotype including distinct surface markers and the ability to differentiate into an effector T cell upon antigen reexposure. CL:0000814 mature NK T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000814 mature NK T lymphocyte|mature natural killer T cell|mature natural killer T lymphocyte|mature NK T-cell|mature NKT cell|mature NK T-lymphocyte|mature natural killer T-cell|mature natural killer T-lymphocyte A mature alpha-beta T cell of a distinct lineage that bears natural killer markers and a T cell receptor specific for a limited set of ligands. NK T cells have activation and regulatory roles particularly early in an immune response. CL:0000815 regulatory T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000815 suppressor T-cell|suppressor T-lymphocyte|regulatory T lymphocyte|suppressor T cell|suppressor T lymphocyte|regulatory T-cell|Treg|regulatory T-lymphocyte A T cell which regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release. CL:0000816 immature B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000816 immature B lymphocyte|newly formed B cell|immature B-cell|immature B-lymphocyte An immature B cell is a B cell that has the phenotype surface IgM-positive and surface IgD-negative, and have not undergone class immunoglobulin class switching or peripheral encounter with antigen and activation. GO:0015197 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015197 GO:0015198 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015198 GO:0015199 amino-acid betaine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015199 glycine betaine/proline porter activity|proline/glycine/betaine:hydrogen/sodium symporter activity|betaine transmembrane transporter activity|betaine/GABA:sodium symporter activity Enables the transfer of betaine from one side of a membrane to the other. Betaine is the N-trimethyl derivative of an amino acid. GO:0015193 L-proline transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015193 Reactome:R-HSA-8870354 glycine betaine/proline porter activity|L-proline transporter activity|proline/glycine/betaine:hydrogen/sodium symporter activity|L-proline permease activity Enables the transfer of L-proline from one side of a membrane to the other. L-proline is pyrrolidine-2-carboxylic acid. GO:0015194 L-serine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015194 Reactome:R-HSA-8932980 threonine/serine:sodium symporter activity|L-serine permease activity|serine transporter activity|L-serine transporter activity Enables the transfer of L-serine from one side of a membrane to the other. L-serine is the L-enantiomer of 2-amino-3-hydroxypropanoic acid. GO:0015195 L-threonine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015195 threonine/serine:sodium symporter activity|L-threonine transporter activity|L-threonine permease activity Enables the transfer of L-threonine from one side of a membrane to the other. L-threonine is (2R*,3S*)-2-amino-3-hydroxybutanoic acid. GO:0015196 L-tryptophan transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015196 Reactome:R-HSA-8870352 valine/tyrosine/tryptophan permease activity|L-tryptophan transporter activity|L-tryptophan permease activity Enables the transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid. CHEBI:6526 Long-chain carboxylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_6526 GO:0015180 L-alanine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015180 L-alanine transporter activity Enables the transfer of L-alanine from one side of a membrane to the other. L-alanine is the L-enantiomer of 2-aminopropanoic acid. GO:0015181 arginine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015181 RHEA:32143 histidine/arginine/lysine/ornithine porter activity|L-arginine transporter activity|arginine permease activity Enables the stereospecific transfer of arginine, 2-amino-5-guanidinopentanoic acid, across a biological membrane. CHEBI:134191 20-oxo-5-O-beta-mycaminosyltylactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134191 GO:0015179 L-amino acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015179 Reactome:R-HSA-212614 L-amino acid transporter activity Enables the transfer of an L-amino acid from one side of a membrane to the other. L-amino acids are the L-enantiomers of amino acids. GO:0015175 neutral amino acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015175 neutral amino acid transporter activity Enables the transfer of neutral amino acids from one side of a membrane to the other. Neutral amino acids have side chains with no charge at pH 7.3. CHEBI:6572 L-lupinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_6572 GO:0015176 obsolete holin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015176 holin OBSOLETE. Primary function of holins appears to be transport of murein hydrolases across the cytoplasmic membrane to the cell wall of bacteria, where these enzymes hydrolyze the cell wall polymer as a prelude to cell lysis. When chromosomally encoded, these enzymes are therefore autolysins. Holins may also facilitate leakage of electrolytes and nutrients from the cell cytoplasm, thereby promoting cell death. Some catalyze export of nucleases. CHEBI:6570 lupeol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_6570 GO:0015177 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015177 GO:0015178 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015178 GO:0015171 amino acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015171 Reactome:R-HSA-379415|Reactome:R-HSA-5660910|Reactome:R-HSA-375790|Reactome:R-HSA-352371|Reactome:R-HSA-379426|Reactome:R-HSA-352232|Reactome:R-HSA-352379|Reactome:R-HSA-375405|Reactome:R-HSA-375417|Reactome:R-HSA-375487|Reactome:R-HSA-5659755|Reactome:R-HSA-352364|Reactome:R-HSA-5659734|Reactome:R-HSA-375473|Reactome:R-HSA-352029|Reactome:R-HSA-352385|Reactome:R-HSA-375776|Reactome:R-HSA-352174|Reactome:R-HSA-376200|Reactome:R-HSA-5660694|Reactome:R-HSA-5653850|Reactome:R-HSA-351963|Reactome:R-HSA-352059|Reactome:R-HSA-5660890|Reactome:R-HSA-352119|Reactome:R-HSA-375770|Reactome:R-HSA-351987|Reactome:R-HSA-352108|Reactome:R-HSA-212642|Reactome:R-HSA-379432|Reactome:R-HSA-375768|Reactome:R-HSA-352347|Reactome:R-HSA-352052|Reactome:R-HSA-5655702|Reactome:R-HSA-378513|Reactome:R-HSA-352158|Reactome:R-HSA-352107|Reactome:R-HSA-210439|Reactome:R-HSA-352354|Reactome:R-HSA-352103|Reactome:R-HSA-352191|Reactome:R-HSA-888592|Reactome:R-HSA-352136|Reactome:R-HSA-5659674|Reactome:R-HSA-352182|Reactome:R-HSA-8952726 amino acid/choline transmembrane transporter activity|hydroxy/aromatic amino acid permease activity|amino acid permease activity|amino acid transporter activity|general amino acid permease activity Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group. GO:0015172 acidic amino acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015172 Reactome:R-HSA-372448 acidic amino acid transporter activity Enables the transfer of acidic amino acids from one side of a membrane to the other. Acidic amino acids have side chains with a negative charge at pH 7.3. CHEBI:6574 lupulone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_6574 GO:0015173 aromatic amino acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015173 hydroxy/aromatic amino acid permease activity|valine/tyrosine/tryptophan permease activity|aromatic amino acid transporter activity Enables the transfer of aromatic amino acids from one side of a membrane to the other. Aromatic amino acids have an aromatic ring. CHEBI:134185 (S)-all-trans-4-hydroxyretinoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134185 GO:0015174 basic amino acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015174 Reactome:R-HSA-8932851|Reactome:R-HSA-8959781 basic amino acid transporter activity|cationic amino acid transmembrane transporter activity|basic amino acid permease activity Enables the transfer of basic amino acids from one side of a membrane to the other. Basic amino acids have side chains with a positive charge at pH 7.3. CHEBI:134186 all-trans-4-oxoretinoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134186 GO:0015190 L-leucine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015190 L-leucine transporter activity|leucine/isoleucine/valine porter activity|leucine/valine/isoleucine permease activity Enables the transfer of L-leucine from one side of a membrane to the other. L-leucine is 2-amino-4-methylpentanoic acid. GO:0015191 L-methionine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015191 L-methionine transporter activity Enables the transfer of L-methionine from one side of a membrane to the other. L-methionine is 2-amino-4-(methylthio)butanoic acid. GO:0015192 L-phenylalanine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015192 L-phenylalanine transporter activity|L-phenylalanine permease activity Enables the transfer of L-phenylalanine from one side of a membrane to the other. L-phenylalanine is 2-amino-3-phenylpropanoic acid. GO:0015186 L-glutamine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015186 asparagine/glutamine permease activity Enables the transfer of L-glutamine from one side of a membrane to the other. L-glutamine is 2-amino-4-carbamoylbutanoic acid. GO:0015187 glycine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015187 proline/glycine/betaine:hydrogen/sodium symporter activity|glycine transporter activity|glycine betaine/proline porter activity Enables the transfer of glycine from one side of a membrane to the other. Glycine is aminoethanoic acid. GO:0015188 L-isoleucine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015188 leucine/isoleucine/valine porter activity|isoleucine/valine:sodium symporter activity|leucine/valine/isoleucine permease activity|L-isoleucine transporter activity Enables the transfer of L-isoleucine from one side of a membrane to the other. L-isoleucine is (2R*,3R*)-2-amino-3-methylpentanoic acid. GO:0015189 L-lysine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015189 lysine permease activity|L-lysine permease|histidine/arginine/lysine/ornithine porter activity Enables the transfer of L-lysine from one side of a membrane to the other. L-lysine is 2,6-diaminohexanoic acid. GO:0015182 L-asparagine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015182 asparagine/glutamine permease activity|L-asparagine transporter activity Enables the transfer of L-asparagine from one side of a membrane to the other. L-asparagine is the L-enantiomer of alpha-aminosuccinamic acid. CHEBI:134198 (R)-tembetarine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134198 GO:0015183 L-aspartate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015183 glutamate/aspartate:sodium symporter activity|glutamate/aspartate porter activity|L-aspartate transporter activity Enables the transfer of L-aspartate from one side of a membrane to the other. L-aspartate is the anion derived from aspartic acid. CHEBI:134199 (S)-tembetarine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134199 GO:0015184 L-cystine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015184 Reactome:R-HSA-5340130 L-cystine transporter activity|cystine/diaminopimelate porter activity Enables the transfer of L-cystine from one side of a membrane to the other. CHEBI:134196 (2R,5Z)-4-methyl-5-[2-(phosphonooxy)ethylidene]-2,5-dihydro-1,3-thiazole-2-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134196 GO:0015185 gamma-aminobutyric acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015185 4-aminobutanoate transporter activity|betaine/GABA:sodium symporter activity|GABA transporter activity|4-aminobutyrate transporter activity Enables the transfer of gamma-aminobutyric acid from one side of a membrane to the other. Gamma-aminobutyric acid is 4-aminobutyrate (GABA). CHEBI:134197 3',5'-cyclic IMP(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134197 GO:0030798 trans-aconitate 2-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030798 MetaCyc:RXN0-2441|RHEA:14969|KEGG_REACTION:R05763|EC:2.1.1.144 S-adenosyl-L-methionine:(E)-prop-1-ene-1,2,3-tricarboxylate 2'-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + trans-aconitate = (E)-3-(methoxycarbonyl)pent-2-enedioate + S-adenosyl-L-homocysteine. GO:0030799 obsolete regulation of cyclic nucleotide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030799 regulation of cyclic nucleotide metabolism OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving cyclic nucleotides. GO:0030796 cycloartenol 24-C-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030796 RHEA:13137|KEGG_REACTION:R05760|MetaCyc:2.1.1.142-RXN|EC:2.1.1.142 sterol C-methyltransferase activity|S-adenosyl-L-methionine:cycloartenol 24-C-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + cycloartenol = (24R)-24-methylcycloart-25-en-3beta-ol + S-adenosyl-L-homocysteine + H(+). GO:0030797 24-methylenesterol C-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030797 KEGG_REACTION:R05776|RHEA:21044|MetaCyc:2.1.1.143-RXN|EC:2.1.1.143 24-methylenelophenol C-24(1)-methyltransferase activity|24-methylenelophenol C-241-methyltransferase activity|SMT2|S-adenosyl-L-methionine:24-methylenelophenol C-methyltransferase activity|SMT(2) activity Catalysis of the reaction: 24-methylidenelophenol + S-adenosyl-L-methionine(1+) = (Z)-24-ethylidenelophenol + S-adenosyl-L-homocysteine + H(+). GO:0015157 oligosaccharide transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015157 endosomal oligosaccharide transporter Enables the transfer of oligosaccharide from one side of a membrane to the other. GO:0015158 raffinose transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015158 raffinose permease Enables the transfer of raffinose from one side of a membrane to the other. Raffinose occurs in plants almost as commonly as sucrose and is present in cereal grains, cotton seeds, and many legumes. It is synthesized from sucrose by transfer of a galactopyranoside from myo-inositol. GO:0015159 polysaccharide transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015159 Enables the transfer of polysaccharides from one side of a membrane to the other. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. GO:0030794 (S)-coclaurine-N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030794 RHEA:17409|MetaCyc:2.1.1.140-RXN|EC:2.1.1.140 S-adenosyl-L-methionine:(S)-coclaurine-N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + (S)-coclaurine = S-adenosyl-L-homocysteine + (S)-N-methylcoclaurine. GO:0015153 rhamnose transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015153 Enables the transfer of rhamnose from one side of a membrane to the other. Rhamnose occurs commonly as a compound of plant glycosides, in polysaccharides of gums and mucilages, and in bacterial polysaccharides. It is also a component of some plant cell wall polysaccharides and frequently acts as the sugar components of flavonoids. CHEBI:134161 N-acylethanolamine 20:4 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134161 GO:0030795 methyl jasmonate methylesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030795 RHEA:13349|MetaCyc:RXN-10768|EC:2.1.1.141 S-adenosyl-L-methionine:jasmonate O-methyltransferase activity|S-adenosyl-L-methionine:jasmonic acid carboxyl methyltransferase activity|jasmonic acid carboxyl methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + a jasmonate = S-adenosyl-L-homocysteine + a methyljasmonate. GO:0015154 disaccharide transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015154 Enables the transfer of disaccharide from one side of a membrane to the other. CHEBI:134162 N-acylethanolamine 20:5 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134162 GO:0015155 lactose transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015155 lactose/glucose efflux transporter activity|lactose permease activity Enables the transfer of lactose from one side of a membrane to the other. Lactose is a disaccharide 4-O-beta-D-galactopyranosyl-D-glucose, and constitutes roughly 5% of the milk in almost all mammals. GO:0030792 methylarsonite methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030792 MetaCyc:2.1.1.138-RXN|EC:2.1.1.- Catalysis of the reaction: S-adenosyl-L-methionine + methylarsonite = S-adenosyl-L-homocysteine + dimethylarsinate. GO:0030793 3'-demethylstaurosporine O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030793 KEGG_REACTION:R05757|RHEA:11696|MetaCyc:2.1.1.139-RXN|EC:2.1.1.139 3'-demethoxy-3'-hydroxystaurosporine O-methyltransferase activity|S-adenosyl-L-methionine:3'-demethylstaurosporine O-methyltransferase activity|staurosporine synthase activity Catalysis of the reaction: 3'-demethylstaurosporine + S-adenosyl-L-methionine = S-adenosyl-L-homocysteine + H(+) + staurosporine. GO:0015156 melibiose transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015156 Enables the transfer of melibiose from one side of a membrane to the other. Melibiose is the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose and occurs as a constituent of the trisaccharide raffinose or in the exudates and nectaries of a number of plants. GO:0030790 chlorophenol O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030790 RHEA:18909|MetaCyc:2.1.1.136-RXN|EC:2.1.1.136 halogenated phenol O-methyltransferase activity|S-adenosyl-L-methionine:trichlorophenol O-methyltransferase activity|trichlorophenol O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + trichlorophenol = S-adenosyl-L-homocysteine + trichloroanisole. CHEBI:134165 N-acylethanolamine 22:6 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134165 GO:0030791 arsenite methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030791 UM-BBD_reactionID:r0805|MetaCyc:2.1.1.137-RXN|EC:2.1.1.137|RHEA:15293|Reactome:R-HSA-5696213|Reactome:R-HSA-5696220 S-adenosyl-L-methionine:arsenic(III) methyltransferase activity|S-adenosyl-L-methionine:methylarsonite As-methyltransferase activity|S-adenosyl-L-methionine:arsenite As-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + arsenite = S-adenosyl-L-homocysteine + methylarsonate. GO:0015150 fucose transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015150 Enables the transfer of fucose from one side of a membrane to the other. Fucose is 6-deoxygalactose and has two enantiomers, D-fucose and L-fucose. GO:0015151 alpha-glucoside transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015151 Enables the transfer of alpha-glucosides from one side of a membrane to the other. Alpha-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in an alpha configuration. GO:0015152 glucose-6-phosphate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015152 Enables the transfer of glucose-6-phosphate from one side of a membrane to the other. Glucose-6-phosphate is a monophosphorylated derivative of glucose with the phosphate group attached to C-6. GO:0030789 precorrin-3B C17-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030789 RHEA:12761|MetaCyc:2.1.1.131-RXN|EC:2.1.1.131 S-adenosyl-L-methionine:precorrin-3B C17-methyltransferase activity|CobJ|precorrin-3 methyltransferase activity|precorrin-3 methylase activity Catalysis of the reaction: S-adenosyl-L-methionine + precorrin-3B = S-adenosyl-L-homocysteine + precorrin 4. GO:0015170 propanediol transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015170 Enables the transfer of propanediol from one side of a membrane to the other. Propanediol is a sweet colorless, viscous, hygroscopic liquid used as an antifreeze and in brake fluid; it is also as a humectant in cosmetics and personal care items, although it can be absorbed through the skin with harmful effects. GO:0030787 inositol 4-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030787 RHEA:23248|MetaCyc:2.1.1.129-RXN|EC:2.1.1.129|KEGG_REACTION:R01190 myo-inositol 4-O-methyltransferase activity|myo-inositol 6-O-methyltransferase activity|S-adenosyl-L-methionine:myo-inositol 4-O-methyltransferase activity|S-adenosyl-L-methionine:1D-myo-inositol 4-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine(1+) + myo-inositol = 1D-4-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H(+). GO:0030788 precorrin-2 C20-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030788 RHEA:16841|MetaCyc:2.1.1.130-RXN|EC:2.1.1.130|KEGG_REACTION:R03948 S-adenosyl-L-methionine:precorrin-4 C20-methyltransferase activity|S-adenosyl-L-methionine--precorrin-2 methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + precorrin-2 = S-adenosyl-L-homocysteine + H(+) + precorrin-3A. GO:0030785 [ribulose-bisphosphate carboxylase]-lysine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030785 MetaCyc:2.1.1.127-RXN|EC:2.1.1.127|RHEA:50996 ribulose-bisphosphate-carboxylase/oxygenase N-methyltransferase activity|S-adenosyl-L-methionine:3-phospho-D-glycerate-carboxy-lyase (dimerizing)-lysine N6-methyltransferase activity|RuBisCO LSMT activity|RuBisCO methyltransferase activity|S-adenosyl-L-methionine:3-phospho-D-glycerate-carboxy-lyase (dimerizing)-lysine 6-N-methyltransferase activity|ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit epsilonN-methyltransferase activity|ribulose-bisphosphate carboxylase-lysine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate carboxylase]-lysine = S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate carboxylase]-N6-methyl-L-lysine. GO:0030786 (RS)-norcoclaurine 6-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030786 MetaCyc:2.1.1.128-RXN|RHEA:19941|EC:2.1.1.128 S-adenosyl-L-methionine:(RS)-norcoclaurine 6-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + (RS)-norcoclaurine = S-adenosyl-L-homocysteine + (RS)-coclaurine. CHEBI:134178 all-trans-4-hydroxyretinoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134178 CHEBI:134179 volatile organic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134179 GO:0015168 glycerol transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015168 Enables the transfer of glycerol from one side of a membrane to the other. Glycerol is 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids. GO:0015169 glycerol-3-phosphate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015169 Enables the transfer of glycerol-3-phosphate from one side of a membrane to the other. Glycerol-3-phosphate is a phosphoric monoester of glycerol. GO:0015164 glucuronoside transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015164 glucuronide transporter activity Enables the transfer of a glucuronosides from one side of a membrane to the other. Glucuronosides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of glucuronate. GO:0030783 [cytochrome c]-methionine S-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030783 MetaCyc:2.1.1.123-RXN|EC:2.1.1.123 cytochrome c-methionine S-methyltransferase activity|S-adenosyl-L-methionine:cytochrome c-methionine S-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + [cytochrome c]-methionine = S-adenosyl-L-homocysteine + [cytochrome c]-S-methyl-methionine. GO:0030784 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030784 RHEA:17789|MetaCyc:2.1.1.116-RXN|EC:2.1.1.116 S-adenosyl-L-methionine:3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 3'-hydroxy-N-methyl-(S)-coclaurine = S-adenosyl-L-homocysteine + (S)-reticuline. GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015165 Enables the transfer of a pyrimidine nucleotide-sugar from one side of a membrane to the other. Pyrimidine nucleotide-sugars are pyrimidine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative. GO:0015166 polyol transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015166 Reactome:R-HSA-429571 sugar/polyol channel activity Enables the transfer of a polyol from one side of a membrane to the other. A polyol is any polyhydric alcohol. GO:0030781 6-O-methylnorlaudanosoline 5'-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030781 RHEA:11892|MetaCyc:2.1.1.121-RXN|EC:2.1.1.121 S-adenosyl-L-methionine:6-O-methylnorlaudanosoline 5'-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 6-O-methylnorlaudanosoline = S-adenosyl-L-homocysteine + nororientaline. GO:0015167 arabitol transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015167 arabinitol transporter activity Enables the transfer of an arabitol from one side of a membrane to the other. Arabitol is the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms. GO:0030782 (S)-tetrahydroprotoberberine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030782 MetaCyc:2.1.1.122-RXN|EC:2.1.1.122|RHEA:12805 S-adenosyl-L-methionine:(S)-7,8,13,14-tetrahydroprotoberberine cis-N-methyltransferase activity|tetrahydroprotoberberine cis-N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + (S)-7,8,13,14-tetrahydroprotoberberine = S-adenosyl-L-homocysteine + cis-N-methyl-(S)-7,8,13,14-tetrahydroprotoberberine. CHEBI:134176 2,3-bis-O-(geranylgeranyl)-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134176 GO:0015160 beta-glucan transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015160 Enables the transfer of beta-glucans from one side of a membrane to the other. Beta-glucans are compounds composed of glucose residues linked by beta-glucosidic bonds. GO:0015161 lipid III floppase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015161 TC:2.A.66.2.3|TC:2.A.66.2.12 capsule polysaccharide transporter activity|undecaprenol-pyrophosphate O-antigen flippase activity|capsular polysaccharide transmembrane transporter activity Enables the transbilayer of capsular-polysaccharides (Und-PP-GlcNAc-ManNAcA-Fuc4NAc (lipid III)) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of ECA. Capsular polysaccharides make up the capsule, a protective structure surrounding some species of bacteria and fungi. GO:0030780 12-hydroxydihydrochelirubine 12-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030780 MetaCyc:2.1.1.120-RXN|RHEA:21092|EC:2.1.1.120|KEGG_REACTION:R04705 S-adenosyl-L-methionine:12-hydroxydihydrochelirubine 12-O-methyltransferase activity Catalysis of the reaction: 12-hydroxydihydrochelirubine + S-adenosyl-L-methionine(1+) = S-adenosyl-L-homocysteine + dihydromacarpine + H(+). GO:0015162 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015162 CHEBI:134175 N-acylserotonin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134175 GO:0015163 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015163 CL:0000889 myeloid suppressor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000889 An immature myeloid leukocyte of heterogeneous phenotype found particularly in cancer and sepsis patients that is capable of suppressing activity of T cells in ex vivo assays. This cell type is CD45-positive, CD11b-positive. CHEBI:17549 5-aminolevulinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17549 CHEBI:17548 alginic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17548 CHEBI:17545 (E)-indol-3-ylacetaldehyde oxime biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17545 CHEBI:17546 (2Z)-5-isopropyl-2-methylhexa-2,5-dienal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17546 CHEBI:17543 1-phospho-alpha-D-galacturonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17543 CHEBI:17544 hydrogencarbonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17544 CHEBI:17541 2-carboxy-D-arabinitol 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17541 CHEBI:17540 methyl beta-D-galactoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17540 CL:0000897 CD4-positive, alpha-beta memory T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000897 CD4-positive, alpha-beta memory T-cell|T4.Mem.Sp|CD4-positive, alpha-beta memory T-lymphocyte|CD4-positive, alpha-beta memory T lymphocyte A CD4-positive, alpha-beta T cell that has differentiated into a memory T cell. CL:0000898 naive T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000898 naive T lymphocyte|naive T-cell|naive T-lymphocyte Mature T cell not yet exposed to antigen with the phenotype CCR7-positive, CD45RA-positive, and CD127-positive. This cell type is also described as being CD25-negative, CD62L-high and CD44-low. CL:0000899 T-helper 17 cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000899 helper T cell type 17|Th17 cell|T(H)-17 cell|IL-17-producing CD4+ T helper|Th17 T-cell|Th17 T-lymphocyte|T helper cells type 17|Th17 T cell|Th17 CD4+ T cell|Th17 T lymphocyte CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive, CXCR3-negative, CCR6-positive, and capable of producing IL-17. CL:0000891 foam cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000891 A type of cell containing lipids in small vacuoles and typically seen in atherolosclerotic lesions, as well as other conditions. CHEBI:17539 9-cis,11-trans-octadecadienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17539 CL:0000892 smooth muscle cell derived foam cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000892 A type of foam cell derived from a smooth muscle cell containing lipids in small vacuoles and typically seen in atherolosclerotic lesions, as well as other conditions. CL:0000893 thymocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000893 immature T-cell|immature T-lymphocyte|thymic lymphocyte|immature T cell|immature T lymphocyte An immature T cell located in the thymus. CHEBI:17536 allantoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17536 CL:0000894 DN1 thymic pro-T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000894 DN1 thymic pro-T-cell|DN1 thymic pro-T-lymphocyte|DN1 thymic progenitor T cell|preT.DN1.Th|DN1 thymocyte|double negative 1|DN1 thymic pro-T lymphocyte A pro-T cell that has the phenotype CD4-negative, CD8-negative, CD44-positive, and CD25-negative. CHEBI:17537 Tyr-Arg biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17537 CHEBI:42504 pentadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_42504 CHEBI:17534 6-amino-2-oxohexanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17534 CL:0000895 naive thymus-derived CD4-positive, alpha-beta T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000895 T.4Nve.Sp|naive thymus-derived CD4-positive, alpha-beta T-cell|naive thymus-derived CD4-positive, alpha-beta T-lymphocyte|Th0|naive thymus-derived CD4-positive, alpha-beta T lymphocyte|naive CD4+ T cell An antigen inexperienced CD4-positive, alpha-beta T cell with the phenotype CCR7-positive, CD127-positive and CD62L-positive. This cell type develops in the thymus. This cell type is also described as being CD25-negative, CD62L-high, and CD44-low. CHEBI:17535 L-arabinopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17535 CL:0000896 activated CD4-positive, alpha-beta T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000896 activated CD4-positive, alpha-beta T-cell|activated CD4-positive, alpha-beta T-lymphocyte|activated CD4-positive, alpha-beta T lymphocyte A recently activated CD4-positive, alpha-beta T cell with the phenotype CD69-positive, CD62L-negative, CD127-negative, and CD25-positive. CHEBI:17532 (S)-6-hydroxynicotine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17532 CHEBI:17533 N-acetyl-L-glutamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17533 CHEBI:17530 L-arogenic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17530 CHEBI:17531 trans-beta-D-glucosyl-2-hydroxycinnamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17531 CL:0000864 tissue-resident macrophage biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000864 resting histiocyte|fixed macrophage A macrophage constitutively resident in a particular tissue under non-inflammatory conditions, and capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells. CL:0000866 thymic macrophage biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000866 A tissue-resident macrophage resident found in the thymus, involved in the clearance of apoptotic thymocytes. CL:0000860 classical monocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000860 inflammatory monocyte A monocyte that responds rapidly to microbial stimuli by secreting cytokines and antimicrobial factors and which is characterized by high expression of CCR2 in both rodents and humans, negative for the lineage markers CD3, CD19, and CD20, and of larger size than non-classical monocytes. CL:0000861 elicited macrophage biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000861 wandering histiocyte|free macrophage A macrophage which develops from an inflammatory monocyte and is recruited into the tissues in response to injury and infection as part of an inflammatory response. Markers include CD11b-positive, CD68-positive, and F4/80-positive. CL:0000862 suppressor macrophage biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000862 A macrophage that suppresses immune responses. CHEBI:17567 O-alkylglycerone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17567 CL:0000863 inflammatory macrophage biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000863 classically activated macrophage|M1 macrophage An elicited macrophage that is recruited into the tissues in response to injury and infection as part of an inflammatory response, expresses high levels of pro-inflammatory cytokines, ROS and NO, and shows potent microbicidal activity. CHEBI:17568 uracil biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17568 CHEBI:17566 indole-3-acetonitrile biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17566 CHEBI:17563 phthalate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17563 CHEBI:17561 L-cysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17561 CHEBI:17562 cytidine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17562 CHEBI:17560 2,2'-iminodipropanoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17560 CL:0000875 non-classical monocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000875 patrolling monocyte|resident monocyte A type of monocyte characterized by low expression of CCR2, low responsiveness to monocyte chemoattractant CCL2/MCP1, low phagocytic activity, and decrease size relative to classical monocytes, but increased co-stimulatory activity. May also play a role in tissue repair. CL:0000878 central nervous system macrophage biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000878 CNS macrophage A tissue-resident macrophage found in the central nervous system. CHEBI:17558 quercitrin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17558 CHEBI:17559 3alpha(S)-strictosidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17559 CHEBI:17556 phaseollidin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17556 CHEBI:17555 1-alkyl-2-acetyl-sn-glycerol 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17555 CHEBI:17552 GDP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17552 CHEBI:17553 O-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17553 CHEBI:17550 UDP-N-acetyl-D-galactosamine 4-sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17550 CHEBI:17551 ecdysone palmitate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17551 CL:0000842 mononuclear cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000842 peripheral blood mononuclear cell|mononuclear leukocyte A leukocyte with a single non-segmented nucleus in the mature form. CL:0000843 follicular B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000843 Fo B-cell|follicular B-cell|follicular B-lymphocyte|Fo B cell|follicular B lymphocyte A resting mature B cell that has the phenotype IgM-positive, IgD-positive, CD23-positive and CD21-positive, and found in the B cell follicles of the white pulp of the spleen or the corticol areas of the peripheral lymph nodes. This cell type is also described as being CD19-positive, B220-positive, AA4-negative, CD43-negative, and CD5-negative. CL:0000844 germinal center B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000844 GC B cell|germinal center B-cell|GC B lymphocyte|germinal center B-lymphocyte|GC B-cell|germinal center B lymphocyte|GC B-lymphocyte A rapidly cycling mature B cell that has distinct phenotypic characteristics and is involved in T-dependent immune responses and located typically in the germinal centers of lymph nodes. This cell type expresses Ly77 after activation. CL:0000845 marginal zone B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000845 MZ B-cell|MZ B-lymphocyte|marginal zone B-cell|marginal zone B-lymphocyte|MZ B cell|MZ B lymphocyte|marginal zone B lymphocyte A mature B cell that is located in the marginal zone of the spleen with the phenotype CD23-negative and CD21-positive and expressing a B cell receptor usually reactive to bacterial cell wall components or senescent self components such as oxidized-LDL. This cell type is also described as being CD19-positive, B220-positive, IgM-high, AA4-negative, CD35-high. CL:0000847 ciliated olfactory receptor neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000847 ciliated sensory neuron|ciliated olfactory sensory neuron An olfactory receptor cell in which the apical ending of the dendrite is a pronounced ciliated olfactory knob. CHEBI:17509 5'-S-methyl-5'-thioadenosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17509 CHEBI:17507 psychosine sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17507 CHEBI:17508 7,8-dihydroxykynurenic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17508 CHEBI:17505 alpha-D-galactosyl-(1->3)-1D-myo-inositol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17505 CHEBI:17506 2-(alpha-D-galactosyl)-sn-glycerol 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17506 CHEBI:17503 N-acyl-D-glutamates(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17503 CHEBI:17504 1-O-acyl-sn-glycero-3-phosphocholine(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17504 CL:0000840 immature conventional dendritic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000840 immature myeloid dendritic cell An immature cell of the conventional dendritic cell lineage, characterized by high levels of antigen uptake via endocytosis, macropinocytosis, and phagocytosis, and typically found resident in the tissues. Markers for this cell are CD80-low, CD86-low, and MHC-II-low. CHEBI:17501 3,3'-dimethoxystilbene-4,4'-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17501 CL:0000841 mature conventional dendritic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000841 mature dendritic cell|mature myeloid dendritic cell A mature cell of the conventional dendritic cell lineage, characterized by a high capacity for antigen presentation and typically found in a lymph node. CHEBI:17502 2-methylpropanal oxime biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17502 CHEBI:17500 7alpha-hydroxycholesterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17500 UBERON:0020550 auricular blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0020550 A blood vessel that supplies or drains an ear. CL:0000855 sensory hair cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000855 hair cell Hair cell is a mechanoreceptor cell that is sensitive to movement of the hair-like projections (stereocilia and kinocilia) which relay the information centrally in the nervous system. CL:0000856 neuromast hair cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000856 Neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. CL:0000857 slow muscle myoblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000857 A skeletal muscle myoblast that differentiates into slow muscle fibers. CL:0000850 serotonergic neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000850 5-HT neuron|5-hydroxytryptamine neuron|serotinergic neuron A neuron that releases serotonin as a neurotransmitter. CL:0000851 neuromast mantle cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000851 Neuromast mantle cell is a non-sensory cell. Neuromast mantle cells surround the neuromast support cells and neuromast hair cells, separating the neuromast from the epidermis, and secrete cupula in which the ciliary bundles of all the hair cells are embedded. CL:0000852 neuromast support cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000852 Neuromast support cell is a non-sensory cell of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; neuromast support cells are surrounded by neuromast mantle cells. CL:0000828 thromboblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000828 A progenitor cell of the thrombocyte, a nucleated blood cell involved in coagulation typically seen in birds and other non-mammalian vertebrates. CL:0000829 basophilic myeloblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000829 A myeloblast committed to the basophil lineage. CL:0000820 B-1a B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000820 CD5(+) B1 cell|CD5-positive B1 cell|B-1a B lymphocyte|B1a B-cell|B1a B-lymphocyte|B-1a B-cell|B1a cell|B1a B cell|B-1a B-lymphocyte|B1a B lymphocyte|CD5+ B1 cell A B-1 B cell that has the phenotype CD5-positive. CL:0000821 B-1b B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000821 B-1b B lymphocyte|B1b B-cell|B1b B-lymphocyte|B-1b B-cell|B1b cell|B1b B cell|B-1b B-lymphocyte|B1b B lymphocyte A B-1 B cell that has the phenotype CD5-negative, but having other phenotypic attributes of a B-1 B cell. CL:0000822 B-2 B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000822 B-2 B-cell|B-2 B-lymphocyte|B2 B-cell|B2 B-lymphocyte|B-0 B cell|B-2 B lymphocyte|B2 cell|B2 B cell|B2 B lymphocyte A conventional B cell subject to antigenic stimulation and dependent on T cell help and with a distinct surface marker expression pattern from B-1 B cells. These cells are CD43-negative. CL:0000823 immature natural killer cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000823 p-NK|immature NK cell A natural killer cell that is developmentally immature and expresses natural killer cell receptors (NKR). CL:0000825 pro-NK cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000825 pro-natural killer cell|preNK cell|null cell|NKP|natural killer cell progenitor A lymphoid progenitor cell that is committed to the natural killer cell lineage, expressing CD122 (IL-15) receptor, but lacking many of the phenotypic characteristics of later stages of natural killer cell development such as expression of NK activating and inhibitory molecules. In human this cell has the phenotype CD34-positive, CD45RA-positive, CD10-positive, CD117-negative, and CD161 negative. CL:0000826 pro-B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000826 pro-B-lymphocyte|pro-B lymphocyte|progenitor B-cell|progenitor B-lymphocyte|pre-B cell (Philadelphia nomenclature)|pre-pro B cell|progenitor B cell|pro-B-cell|progenitor B lymphocyte A progenitor cell of the B cell lineage, with some lineage specific activity such as early stages of recombination of B cell receptor genes, but not yet fully committed to the B cell lineage until the expression of PAX5 occurs. CL:0000827 pro-T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000827 pro-T lymphocyte|DN1 cell|progenitor T cell|DN1 thymocyte|TN1 cell A lymphoid progenitor cell of the T cell lineage, with some lineage specific marker expression, but not yet fully committed to the T cell lineage. CHEBI:17529 kievitone hydrate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17529 CHEBI:17527 1,2,3,6-tetrakis-O-galloyl-beta-D-glucose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17527 CHEBI:17528 all-trans-hexaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17528 CHEBI:17525 testolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17525 CHEBI:17526 1-phosphatidyl-1D-myo-inositol 4-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17526 CHEBI:17524 6-alkylaminopurine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17524 CHEBI:17521 (-)-quinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17521 CHEBI:17522 alditol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17522 CHEBI:17520 phenylthioacetohydroximic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17520 CL:0000839 myeloid lineage restricted progenitor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000839 myeloid progenitor cell A progenitor cell restricted to the myeloid lineage. CL:0000831 mast cell progenitor biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000831 colony forming unit mast cell|CFU-MC|CFU-Mast|MCP A progenitor cell of the mast cell lineage. Markers for this cell are FceRIa-low, CD117-positive, CD9-positive, T1/ST2-positive, SCA1-negative, and lineage-negative. CL:0000832 eosinophilic myeloblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000832 A myeloblast committed to the eosinophil lineage. CL:0000833 eosinophilic promyelocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000833 A promyelocyte committed to the eosinophil lineage. CL:0000834 neutrophil progenitor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000834 neutrophil stem cell A progenitor cell of the neutrophil lineage. CL:0000835 myeloblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000835 The most primitive precursor in the granulocytic series, having fine, evenly distributed chromatin, several nucleoli, a high nuclear-to-cytoplasmic ration (5:1-7:1), and a nongranular basophilic cytoplasm. They reside in the bone marrow. CL:0000836 promyelocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000836 A precursor in the granulocytic series, being a cell intermediate in development between a myeloblast and myelocyte, that has distinct nucleoli, a nuclear-to-cytoplasmic ratio of 5:1 to 3:1, and containing a few primary cytoplasmic granules. Markers for this cell are fucosyltransferase FUT4-positive, CD33-positive, integrin alpha-M-negative, low affinity immunoglobulin gamma Fc region receptor III-negative, and CD24-negative. CL:0000837 hematopoietic multipotent progenitor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000837 MPP|hemopoietic progenitor cell A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans. CL:0000838 lymphoid lineage restricted progenitor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000838 lymphoid progenitor cell A progenitor cell restricted to the lymphoid lineage. CHEBI:17519 N-methyl-L-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17519 CHEBI:17516 but-1-ene-1,2,4-tricarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17516 CHEBI:17517 phosphatidylglycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17517 CHEBI:17514 cyanide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17514 CHEBI:17515 L-gamma-glutamyl-L-cysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17515 CHEBI:17512 methyl 2-O-alpha-L-fucopyranosyl-beta-D-galactoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17512 CL:0000830 basophilic promyelocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000830 A promyelocyte committed to the basophil lineage. CHEBI:17510 dTDP-D-fucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17510 CHEBI:17511 3-O-L-alanyl-1-O-phosphatidylglycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17511 GO:0005736 RNA polymerase I complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005736 DNA-directed RNA polymerase I activity|DNA-directed RNA polymerase I complex RNA polymerase I, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces rRNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase III and others of which are also found in RNA polymerases II and III. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template. GO:0005737 cytoplasm biolink:CellularComponent go-plus goslim_metagenomics|goslim_generic|goslim_chembl|goslim_yeast|goslim_candida|goslim_pir|goslim_plant http://purl.obolibrary.org/obo/GO_0005737 Wikipedia:Cytoplasm All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0005734 obsolete box C + D snoRNP protein biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005734 box C + D snoRNP protein OBSOLETE. (Was not defined before being made obsolete). GO:0005735 obsolete box H + ACA snoRNP protein biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005735 box H + ACA snoRNP protein OBSOLETE. (Was not defined before being made obsolete). GO:0005732 sno(s)RNA-containing ribonucleoprotein complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0005732 small nucleolar ribonucleoprotein|small ribonucleoprotein|sRNP|snoRNP|small nucleolar ribonucleoprotein complex|small ribonucleoprotein protein complex A ribonucleoprotein complex that contains an RNA molecule of the snoRNA family and associated proteins. Many are involved in a step of processing of rRNA molecules: cleavage, 2'-O-methylation, or pseudouridylation, but other RNA types can be targets as well. The majority fall into one of two classes, box C/D type or box H/ACA type, which are conserved across eukaryotes and archaea. Other members include the telomerase RNA and the ribonuclease MRP RNA. GO:0005733 obsolete small nucleolar RNA biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005733 snoRNA|small nucleolar RNA OBSOLETE. (Was not defined before being made obsolete). GO:0005730 nucleolus biolink:CellularComponent go-plus goslim_generic|goslim_chembl|goslim_candida|goslim_yeast|goslim_plant|goslim_pir|goslim_drosophila|goslim_aspergillus http://purl.obolibrary.org/obo/GO_0005730 NIF_Subcellular:sao1820400233|Wikipedia:Nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. GO:0005731 nucleolus organizer region biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005731 Wikipedia:Nucleolus_organizer_region nucleolus organiser region|NOR|nucleolus organizer complex A region of a chromosome where nucleoli form during interphase, and where genes encoding the largest rRNA precursor transcript are tandemly arrayed. CHEBI:42471 forskolin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_42471 GO:0005739 mitochondrion biolink:CellularComponent go-plus goslim_drosophila|goslim_aspergillus|goslim_generic|goslim_flybase_ribbon|goslim_chembl|goslim_mouse|goslim_agr|goslim_candida|goslim_yeast|goslim_pir|goslim_plant http://purl.obolibrary.org/obo/GO_0005739 Wikipedia:Mitochondrion|NIF_Subcellular:sao1860313010 mitochondria A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. GO:0005747 mitochondrial respiratory chain complex I biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005747 A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone. PO:0000077 sclerenchyma cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000077 célula esclerenquimática (Spanish, exact)|厚膜組織 細胞 (Japanese, exact) A ground tissue cell (PO:0025030) with a lignified secondary cell wall. GO:0005748 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005748 GO:0005745 m-AAA complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005745 Protease complex of the mitochondrial inner membrane that is involved in mitochondrial protein turnover and in processing of proteins imported into mitochondria. GO:0005746 mitochondrial respirasome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005746 mitochondrial respirasome|mitochondrial electron transport chain|mitochondrial respiratory supercomplex|mitochondrial respiratory chain supercomplex|mitochondrial respiratory chain The protein complexes that form the mitochondrial electron transport system (the respiratory chain), associated with the inner mitochondrial membrane. The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient. GO:0005743 mitochondrial inner membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005743 NIF_Subcellular:sao1371347282|Wikipedia:Inner_mitochondrial_membrane inner mitochondrion membrane|mitochondrion inner membrane|inner mitochondrial membrane The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae. GO:0005744 TIM23 mitochondrial import inner membrane translocase complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0005744 Tim23 complex|mitochondrial inner membrane pre-sequence translocase complex|mitochondrial inner membrane presequence translocase complex|mitochondrial inner membrane translocase complex The protein transport machinery of the mitochondrial inner membrane that typically transports proteins that possess a matrix-targeting N-terminal presequence. The TIM23 complex contains three essential Tim proteins: Tim17 and Tim23 are thought to build a preprotein translocation channel while Tim44 interacts transiently with the matrix heat-shock protein Hsp70 to form an ATP-driven import motor. GO:0005741 mitochondrial outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005741 Wikipedia:Outer_mitochondrial_membrane|NIF_Subcellular:sao1289741256 outer mitochondrial membrane|outer mitochondrion membrane|mitochondrion outer membrane The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope. GO:0005742 mitochondrial outer membrane translocase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005742 GIP complex|TOM complex|mitochondrion outer membrane translocase complex A large complex of the mitochondrial outer membrane that mediates transport of proteins into all mitochondrial compartments. GO:0005740 mitochondrial envelope biolink:CellularComponent go-plus goslim_candida|goslim_yeast http://purl.obolibrary.org/obo/GO_0005740 The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space. CHEBI:42465 ethanesulfonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_42465 CHEBI:17499 hydrogen donor biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17499 CHEBI:17497 glycolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17497 PO:0000084 plant sperm cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000084 植物精子細胞 (Japanese, exact)|male gamete (exact)|sperm cell (broad)|célula espermática o esperma (Spanish, exact)|microgamete (exact)|sperm nucleus (related) A gamete (PO:0025006) produced by an antheridium (PO:0025125) or a microgametophyte (PO:0025280). CHEBI:17495 cholesteryl beta-D-glucoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17495 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005749 mitochondrial fumarate reductase complex A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains the four polypeptide subunits of succinate dehydrogenase, flavin-adenine dinucleotide and iron-sulfur. Catalyzes the oxidation of succinate by ubiquinone. Connects the TCA cycle with the respiratory chain. CHEBI:17494 CDP-4-dehydro-6-deoxy-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17494 GO:0005714 early recombination nodule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005714 An electron dense structure that is associated with meiotic chromosomes in leptotene or zygotene during meiosis I. GO:0005715 late recombination nodule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005715 An electron dense structure that is associated with meiotic chromosomes in pachytene during meiosis I. GO:0005712 chiasma biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005712 Wikipedia:Chiasma_(genetics) A connection formed between chromatids, visible during meiosis, thought to be the point of the interchange involved in crossing-over. GO:0005713 recombination nodule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005713 An electron dense structure that is associated with meiotic chromosomes. GO:0005710 obsolete metaphase chromosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005710 metaphase chromosome OBSOLETE. A chromosome found in the cell during metaphase. Typically, sister chromatids are held together at their centromeres and chromosomes are covered with a large number of molecules, including ribonucleoproteins. GO:0005711 obsolete meiotic chromosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005711 meiotic chromosome OBSOLETE. A chromosome involved in the process of meiosis. PO:0000071 companion cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000071 伴細胞 (Japanese, exact)|célula acompañiante (Spanish, exact)|minor vein companion cell (exact) A parenchyma cell (PO:0000074) that is adjacent to a sieve tube element (PO:0000289) and arises from the same phloem mother cell (PO:0000400) as the sieve tube element. GO:0005718 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005718 PO:0000074 parenchyma cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000074 célula parenquimática (Spanish, exact)|柔組織細胞 (Japanese, exact) A relatively unspecialized ground tissue cell with a nucleate protoplast. GO:0005719 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005719 GO:0005716 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005716 PO:0000075 collenchyma cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000075 célula colenquimática (Spanish, exact)|厚角組織 細胞 (Japanese, exact) An elongated plant cell with unevenly thickened non-lignified primary walls that is alive at maturity. GO:0005717 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005717 PO:0000055 bud biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000055 yema (Spanish, exact)|adventitious bud (narrow)|芽 (Japanese, exact) An undeveloped shoot system (PO:0009006). GO:0005725 intercalary heterochromatin biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005725 Any of the regions of heterochromatin that form a reproducible set of dense bands scattered along the euchromatic arms in polytene chromosomes. CHEBI:66470 (+)-sesamin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66470 GO:0005726 perichromatin fibrils biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005726 Structures of variable diameter visible in the nucleoplasm by electron microscopy, mainly observed near the border of condensed chromatin. The fibrils are enriched in RNA, and are believed to be sites of pre-mRNA splicing and polyadenylylation representing the in situ form of nascent transcripts. GO:0005723 alpha-heterochromatin biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005723 A small, compact region of heterochromatin located in the middle of the polytene chromosome chromocenter, which undergoes little or no replication during polytenization. GO:0005724 obsolete nuclear telomeric heterochromatin biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005724 OBSOLETE. Heterochromatic regions of the chromosome found at the telomeres of a chromosome in the nucleus. GO:0005721 pericentric heterochromatin biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005721 nuclear centric heterochromatin|nuclear cluster|centric heterochromatin|nuclear pericentric heterochromatin|centromeric heterochromatin Heterochromatin that is located adjacent to the CENP-A rich centromere 'central core' and characterized by the modified histone H3K9me3. GO:0005722 beta-heterochromatin biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005722 A diffusely banded region of heterochromatin located between euchromatin and alpha-heterochromatin in the polytene chromosome chromocenter; normally replicated during polytenization. GO:0005720 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005720 PO:0000062 stomatal initial cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000062 気孔始原細胞 (Japanese, exact)|stomatal initial (exact)|inicial estomática (meristemoide inicial) (Spanish, exact)|stomatal meristemoid (exact) An epidermal initial cell (PO:0000349) that undergoes several rounds of uneven division, each time giving rise to a larger daughter cell that differentiates into an epidermal ground cell and a smaller daughter cell that remains meristematic, until the meristematic cell (PO:0004010) differentiates into a guard mother cell (PO:0000351). GO:0005729 2-micrometer circle DNA biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005729 A plasmid commonly found in Saccharomyces, inherited in a non-Mendelian manner and often present in 100-400 copies. GO:0005727 extrachromosomal circular DNA biolink:CellularComponent go-plus goslim_metagenomics http://purl.obolibrary.org/obo/GO_0005727 Circular DNA structures that are not part of a chromosome. GO:0005728 extrachromosomal rDNA circle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005728 extrachromosomal ribosomal DNA circle Circular DNA molecules encoding ribosomal RNA that are replicated independently of chromosomal replication. These molecules originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats. CHEBI:17470 2-O-caffeoylglucaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17470 UBERON:0005032 mucosa of lower lip biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005032 mucosa of organ of lower lip|lower lip organ mucosa|lower labial mucosa|lower lip mucosa of organ|organ mucosa of lower lip|lower lip mucous membrane|lower lip mucosa|mucous membrane of lower lip A mucosa that is part of a lower lip [Automatically generated definition]. UBERON:0005033 mucosa of gallbladder biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005033 gallbladder organ mucosa|gall bladder mucosa|gall bladder mucosa of organ|mucous membrane of gallbladder|gall bladder mucous membrane|tunica mucosa (vesica biliaris)|mucosa of organ of gallbladder|organ mucosa of gall bladder|gallbladder mucosa|tunica mucosa vesicae biliaris|gall bladder organ mucosa|organ mucosa of gallbladder|gallbladder mucosa of organ|mucosa of organ of gall bladder|gallbladder mucous membrane|mucosa of gall bladder|mucous membrane of gall bladder A mucosa that is part of a gallbladder [Automatically generated definition]. UBERON:0005031 mucosa of upper lip biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005031 mucosa of organ of upper lip|upper labial mucosa|upper lip organ mucosa|organ mucosa of upper lip|upper lip mucosa of organ|upper lip mucous membrane|upper lip mucosa|mucous membrane of upper lip A mucosa that is part of a upper lip [Automatically generated definition]. CHEBI:42438 2-methoxy-4-vinylphenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_42438 CHEBI:17468 (4-bromophenylsulfanyl)pyruvate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17468 CHEBI:17469 N-adenylylanthranilic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17469 CHEBI:17466 GDP-D-mannuronate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17466 CHEBI:17467 4-(dimethylamino)phenylazoxybenzene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17467 CHEBI:17464 L-galactono-1,4-lactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17464 CHEBI:17465 phaseollidin hydrate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17465 UBERON:0005038 mucosa of segmental bronchus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005038 tertiary bronchus mucosa of organ|organ mucosa of tertiary bronchus|segmental bronchial mucosa|mucosa of organ of segmental bronchus|tertiary bronchus mucosa|tertiary bronchus mucous membrane|mucous membrane of segmental bronchus|segmental bronchus organ mucosa|segmental bronchus mucosa of organ|mucous membrane of tertiary bronchus|segmental bronchus mucous membrane|mucosa of tertiary bronchus|tertiary bronchus organ mucosa|mucosa of organ of tertiary bronchus|segmental bronchus mucosa|organ mucosa of segmental bronchus A mucosa that is part of a segmental bronchus [Automatically generated definition]. UBERON:0005039 mucosa of bronchiole biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005039 organ mucosa of lobular bronchiole|lobular bronchiole organ mucosa|mucosa of organ of bronchiole|bronchiole organ mucosa|mucous membrane of bronchiole|mucosa of organ of lobular bronchiole|bronchiole mucosa of organ|mucosa of lobular bronchiole|lobular bronchiole mucosa|mucous membrane of lobular bronchiole|bronchiole mucous membrane|lobular bronchiole mucosa of organ|bronchiole mucosa|lobular bronchiole mucous membrane|organ mucosa of bronchiole A mucosa that is part of a bronchiole [Automatically generated definition]. CHEBI:17460 lipoamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17460 UBERON:0005037 mucosa of lobar bronchus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005037 mucosa of secondary bronchus|lobar bronchus mucosa of organ|mucous membrane of secondary bronchus|secondary bronchus mucosa|secondary bronchus mucosa of organ|lobar bronchus mucous membrane|lobar bronchus mucosa|secondary bronchus mucous membrane|organ mucosa of lobar bronchus|organ mucosa of secondary bronchus|secondary bronchus organ mucosa|lobar bronchial mucosa|mucosa of organ of lobar bronchus|lobar bronchus organ mucosa|mucosa of organ of secondary bronchus|mucous membrane of lobar bronchus A mucosa that is part of a lobar bronchus [Automatically generated definition]. GO:0005703 polytene chromosome puff biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005703 A swelling at a site along the length of a polytene chromosome, thought to be the site of active transcription. GO:0005704 polytene chromosome band biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005704 A stretch of densely packed chromatin along the polytene chromosome, visible as a morphologically distinct band. GO:0005701 polytene chromosome chromocenter biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005701 polytene chromosome chromocentre A region at which the centric regions of polytene chromosomes are joined together. GO:0005702 polytene chromosome weak point biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005702 constriction A region of the polytene chromosome where the diameter is considerably decreased, probably resulting from local differences in chromosome organization. GO:0005700 polytene chromosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005700 Wikipedia:Polytene_chromosome A type of chromosome in a polyploid cell, formed when multiple copies of homologous chromosomes are aligned side by side to give a giant chromosome in which distinct chromosome bands are readily visible. UBERON:0005024 mucosa of soft palate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005024 soft palate mucosa|soft palate mucosa of organ|organ mucosa of soft palate|soft palate mucous membrane|soft palate organ mucosa|mucous membrane of soft palate|mucosa of organ of soft palate A mucosa that is part of a soft palate [Automatically generated definition]. UBERON:0005022 mucosa of nasopharynx biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005022 nasal part of pharynx mucosa|nasopharynx mucosa|mucosa of organ of rhinopharynx|nasopharynx mucosa of organ|organ mucosa of nasopharynx|mucosa of rhinopharynx|mucous membrane of rhinopharynx|nasal part of pharynx mucosa of organ|organ mucosa of nasal part of pharynx|nasopharynx mucous membrane|rhinopharynx mucosa of organ|rhinopharynx organ mucosa|nasal part of pharynx mucous membrane|nasal part of pharynx organ mucosa|rhinopharynx mucous membrane|nasopharynx organ mucosa|mucous membrane of nasopharynx|organ mucosa of rhinopharynx|mucous membrane of nasal part of pharynx|mucosa of nasal part of pharynx|mucosa of organ of nasopharynx|rhinopharynx mucosa|mucosa of organ of nasal part of pharynx A mucosa that is part of a nasopharynx [Automatically generated definition]. CHEBI:17459 D-iditol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17459 UBERON:0005020 mucosa of tongue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005020 lingual mucosa|mucosa of organ of tongue|mucous membrane of tongue|tongue organ mucosa|tunica mucosa linguae|tongue mucosa of organ|tongue mucous membrane|tongue mucosa|organ mucosa of tongue A mucosa that is part of a tongue [Automatically generated definition]. CHEBI:17457 14'-apo-beta-carotenal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17457 CHEBI:17458 N-methyltyramine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17458 CHEBI:17455 N-(2,3-dihydroxybenzoyl)-L-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17455 CHEBI:17456 dithioerythritol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17456 CHEBI:17453 methylmalonate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17453 GO:0005709 obsolete prophase chromosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005709 prophase chromosome OBSOLETE. A chromosome found in the cell during prophase. CHEBI:17454 UDP-L-rhamnose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17454 GO:0005707 obsolete interphase chromosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005707 interphase chromosome OBSOLETE. A chromosome found in the cell during interphase of the cell cycle. Chromosomes are usually decondensed during interphase and each long DNA molecule in a chromosome is divided into a large number of discrete domains that are folded differently. GO:0005708 obsolete mitotic chromosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005708 mitotic chromosome OBSOLETE. A chromosome involved in the process of mitosis. GO:0005705 polytene chromosome interband biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005705 A stretch of less tightly packed chromatin along the polytene chromosome, found between bands. UBERON:0005026 mucosa of middle ear biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005026 mucosa of organ of middle ear|middle ear mucosa|mucous membrane of middle ear|middle ear mucosa of organ|middle ear mucous membrane|tunica mucosa cavitatis tympanicae|middle ear organ mucosa|organ mucosa of middle ear|mucosa of tympanic cavity A mucosa that is part of a middle ear [Automatically generated definition]. CHEBI:17450 cis-4-coumaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17450 GO:0005706 polytene chromosome ectopic fiber biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005706 polytene chromosome ectopic fibre A thread-like connection joining two regions of ectopically paired polytene chromosomes. CHEBI:17491 S-(2-hydroxyacyl)glutathione biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17491 CHEBI:17490 O-palmitoyl-L-carnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17490 UBERON:0005012 mucosa of left uterine tube biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005012 left uterine tube mucous membrane|left fallopian tube mucosa of organ|organ mucosa of left fallopian tube|left uterine tube organ mucosa|left oviduct organ mucosa|organ mucosa of left oviduct|left fallopian tube mucous membrane|left fallopian tube mucosa|mucous membrane of left uterine tube|mucosa of organ of left oviduct|mucosa of organ of left uterine tube|mucous membrane of left fallopian tube|left uterine tube mucosa|mucosa of left fallopian tube|left oviduct mucosa|mucosa of left oviduct|mucous membrane of left oviduct|mucosa of organ of left fallopian tube|left oviduct mucosa of organ|left uterine tube mucosa of organ|organ mucosa of left uterine tube|left fallopian tube organ mucosa|left oviduct mucous membrane A mucosa that is part of a left uterine tube [Automatically generated definition]. UBERON:0005013 mucosa of male urethra biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005013 male urethra mucosa|mucosa of organ of male urethra|mucous membrane of male urethra|male urethra mucosa of organ|male urethra organ mucosa|male urethra mucous membrane|organ mucosa of male urethra A mucosa that is part of a male urethra [Automatically generated definition]. UBERON:0005010 mucosa of neck of urinary bladder biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005010 mucosa of organ of bladder neck|organ mucosa of neck of urinary bladder|neck of urinary bladder mucosa of organ|bladder neck mucosa|neck of bladder mucosa|mucosa of bladder neck|mucosa of organ of vesical neck|mucous membrane of bladder neck|mucosa of organ of urinary bladder neck|neck of urinary bladder mucous membrane|neck of bladder mucosa of organ|organ mucosa of neck of bladder|bladder neck mucosa of organ|mucosa of vesical neck|neck of urinary bladder mucosa|mucosa of urinary bladder neck|mucous membrane of vesical neck|mucous membrane of urinary bladder neck|neck of bladder mucous membrane|bladder neck mucous membrane|vesical neck mucosa of organ|urinary bladder neck mucosa of organ|vesical neck organ mucosa|mucous membrane of neck of urinary bladder|vesical neck mucous membrane|urinary bladder neck mucous membrane|bladder neck organ mucosa|organ mucosa of bladder neck|neck of bladder organ mucosa|mucosa of organ of neck of urinary bladder|mucous membrane of neck of bladder|mucosa of neck of bladder|organ mucosa of vesical neck|neck of urinary bladder organ mucosa|organ mucosa of urinary bladder neck|urinary bladder neck mucosa|mucosa of organ of neck of bladder|vesical neck mucosa A mucosa that is part of a neck of urinary bladder [Automatically generated definition]. UBERON:0005011 mucosa of right uterine tube biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005011 organ mucosa of right fallopian tube|organ mucosa of right oviduct|right oviduct mucosa of organ|right fallopian tube organ mucosa|mucosa of organ of right uterine tube|right oviduct mucosa|right oviduct mucous membrane|mucous membrane of right uterine tube|mucosa of organ of right fallopian tube|right uterine tube organ mucosa|right uterine tube mucosa of organ|mucosa of right fallopian tube|mucous membrane of right fallopian tube|mucous membrane of right oviduct|right uterine tube mucous membrane|mucosa of right oviduct|right fallopian tube mucosa|right fallopian tube mucosa of organ|right oviduct organ mucosa|mucosa of organ of right oviduct|right fallopian tube mucous membrane|organ mucosa of right uterine tube|right uterine tube mucosa A mucosa that is part of a right uterine tube [Automatically generated definition]. CHEBI:17488 scopoletin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17488 CHEBI:17489 3',5'-cyclic AMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17489 CHEBI:17486 (S)-atropine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17486 UBERON:0005019 mucosa of palate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005019 oral roof mucosa of organ|organ mucosa of oral roof|palate mucosa|roof of mouth mucous membrane|oral roof organ mucosa|oral roof mucous membrane|roof of mouth organ mucosa|mucosa of organ of palate|mucous membrane of palate|mucous membrane of roof of mouth|mucosa of roof of mouth|palate mucosa of organ|mucous membrane of oral roof|oral roof mucosa|mucosa of organ of roof of mouth|mucosa of oral roof|palate organ mucosa|roof of mouth mucosa|palate mucous membrane|mucosa of organ of oral roof|organ mucosa of palate|organ mucosa of roof of mouth|roof of mouth mucosa of organ A mucosa that is part of a palate [Automatically generated definition]. CHEBI:17484 benzyl isothiocyanate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17484 CHEBI:17485 homocystine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17485 UBERON:0005014 mucosa of female urethra biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005014 female urethra mucosa|mucosa of organ of female urethra|mucous membrane of female urethra|female urethra mucosa of organ|female urethra organ mucosa|female urethra mucous membrane|organ mucosa of female urethra A mucosa that is part of a female urethra [Automatically generated definition]. CHEBI:17482 L-cystathionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17482 CHEBI:354984 candicidin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_354984 UBERON:0005001 mucosa of common hepatic duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005001 organ mucosa of hepatic duct|common hepatic duct organ mucosa|common hepatic duct mucous membrane|mucosa of organ of hepatic duct|hepatic duct organ mucosa|mucous membrane of common hepatic duct|mucosa of hepatic duct|mucous membrane of hepatic duct|common hepatic duct mucosa|hepatic duct mucosa of organ|mucosa of organ of common hepatic duct|hepatic duct mucous membrane|common hepatic ductal mucosa|hepatic duct mucosa|organ mucosa of common hepatic duct|common hepatic duct mucosa of organ A mucosa that is part of a common hepatic duct [Automatically generated definition]. UBERON:0005002 mucosa of right hepatic duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005002 right hepatic duct mucosa|mucosa of organ of right hepatic duct|right hepatic ductal mucosa|mucous membrane of right hepatic duct|right hepatic duct mucosa of organ|right hepatic duct organ mucosa|right hepatic duct mucous membrane|organ mucosa of right hepatic duct A mucosa that is part of a right hepatic duct [Automatically generated definition]. UBERON:0005000 mucosa of common bile duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005000 mucosa of organ of common bile duct|organ mucosa of ductus choledochus (biliaris)|ductus choledochus (biliaris) mucosa of organ|mucous membrane of common bile duct|common bile duct mucosa|common bile duct mucosa of organ|ductus choledochus (biliaris) mucous membrane|ductus choledochus (biliaris) mucosa|common bile duct mucous membrane|common bile ductal mucosa|mucous membrane of ductus choledochus (biliaris)|organ mucosa of common bile duct|mucosa of ductus choledochus (biliaris)|common bile duct organ mucosa|mucosa of organ of ductus choledochus (biliaris)|ductus choledochus (biliaris) organ mucosa A mucosa that is part of a common bile duct [Automatically generated definition]. CHEBI:17479 enol-oxaloacetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17479 CHEBI:17477 uracil-5-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17477 CHEBI:17478 aldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17478 CHEBI:17475 aminomalonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17475 CHEBI:17476 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17476 CHEBI:17473 1-alkyl-2-acetyl-3-acyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17473 UBERON:0005005 mucosa of left ureter biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005005 left ureter mucosa of organ|organ mucosa of left ureter|left ureter mucous membrane|left ureter mucosa|mucous membrane of left ureter|left ureteral mucosa|mucosa of organ of left ureter|left ureter organ mucosa A mucosa that is part of a left ureter [Automatically generated definition]. UBERON:0005006 mucosa of renal pelvis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005006 mucosa of organ of kidney pelvis|organ mucosa of renal pelvis|mucosa of organ of pelvis of ureter|pelvis of ureter mucosa|mucosa of pelvis of ureter|kidney pelvis mucosa|mucous membrane of pelvis of ureter|organ mucosa of kidney pelvis|kidney pelvis mucosa of organ|mucosa of organ of renal pelvis|pelvis of ureter mucosa of organ|tunica mucosa pelvis renalis|renal pelvic mucosa|renal pelvis organ mucosa|kidney pelvis mucous membrane|mucous membrane of renal pelvis|pelvis of ureter mucous membrane|renal pelvis mucosa of organ|pelvis of ureter organ mucosa|organ mucosa of pelvis of ureter|kidney pelvis organ mucosa|renal pelvis mucous membrane|mucous membrane of kidney pelvis|mucosa of kidney pelvis|renal pelvis mucosa A mucosa that is part of a renal pelvis [Automatically generated definition]. CHEBI:17474 estrone 3-sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17474 UBERON:0005003 mucosa of left hepatic duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005003 left hepatic duct mucous membrane|left hepatic ductal mucosa|left hepatic duct organ mucosa|mucous membrane of left hepatic duct|mucosa of organ of left hepatic duct|left hepatic duct mucosa|left hepatic duct mucosa of organ|organ mucosa of left hepatic duct A mucosa that is part of a left hepatic duct [Automatically generated definition]. UBERON:0005004 mucosa of right ureter biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005004 right ureteral mucosa|organ mucosa of right ureter|right ureter organ mucosa|mucosa of organ of right ureter|mucous membrane of right ureter|right ureter mucosa|right ureter mucosa of organ|right ureter mucous membrane A mucosa that is part of a right ureter [Automatically generated definition]. PO:0000002 anther wall biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000002 pollen sac wall (exact)|Zea anther wall (narrow)|pared de la antera (Spanish, exact)|葯壁 (Japanese, exact)|Poaceae anther wall (narrow) A microsporangium wall (PO:0025307) that is part of an anther (PO:0009066). GO:0030778 columbamine O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030778 KEGG_REACTION:R03721|MetaCyc:2.1.1.118-RXN|EC:2.1.1.118|RHEA:15373 S-adenosyl-L-methionine:columbamine O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + columbamine = S-adenosyl-L-homocysteine + H(+) + palmatine. PO:0000003 whole plant biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000003 prothalli (narrow)|shrub (narrow)|vine (narrow)|herb (narrow)|colony (related)|植物体全体 (Japanese, exact)|frutices (narrow)|planta entera (Spanish, exact)|suffrutices (narrow)|liana (narrow)|ramet (broad)|woody clump (narrow)|prothallus (narrow)|tree (narrow)|frutex (narrow)|prothallium (narrow)|suffrutex (narrow)|clonal colony (related)|sporophyte (narrow)|gametophyte (narrow)|seedling (narrow)|genet (broad)|bush (narrow) A plant structure (PO:0005679) which is a whole organism. GO:0030779 10-hydroxydihydrosanguinarine 10-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030779 KEGG_REACTION:R04707|MetaCyc:2.1.1.119-RXN|EC:2.1.1.119|RHEA:18541 S-adenosyl-L-methionine:10-hydroxydihydrosanguinarine 10-O-methyltransferase activity Catalysis of the reaction: 10-hydroxydihydrosanguinarine + S-adenosyl-L-methionine(1+) = S-adenosyl-L-homocysteine + dihydrochelirubine + H(+). GO:0030776 (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030776 RHEA:13005|MetaCyc:2.1.1.115-RXN|EC:2.1.1.115 norreticuline N-methyltransferase activity|S-adenosyl-L-methionine:(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase activity|(RS)-tetrahydrobenzylisoquinoline N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline = S-adenosyl-L-homocysteine + N-methyl-(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline. GO:0030777 (S)-scoulerine 9-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030777 RHEA:23808|KEGG_REACTION:R03835|MetaCyc:2.1.1.117-RXN|EC:2.1.1.117 S-adenosyl-L-methionine:(S)-scoulerine 9-O-methyltransferase activity|S-adenosyl-L-methionine:(S)-scoclaurine 9-O-methyltransferase activity Catalysis of the reaction: (S)-scoulerine + S-adenosyl-L-methionine(1+) = (S)-tetrahydrocolumbamine + S-adenosyl-L-homocysteine + H(+). GO:0030774 anthranilate N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030774 MetaCyc:ANTHRANILATE-N-METHYLTRANSFERASE-RXN|KEGG_REACTION:R00984|RHEA:12180|EC:2.1.1.111 S-adenosyl-L-methionine:anthranilate N-methyltransferase activity|anthranilic acid N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + anthranilate = N-methylanthranilate + S-adenosyl-L-homocysteine + H(+). GO:0030775 glucuronoxylan 4-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030775 RHEA:20413|MetaCyc:GLUCURONOXYLAN-4-O-METHYLTRANSFERASE-RXN|EC:2.1.1.112 S-adenosyl-L-methionine:glucuronoxylan-D-glucuronate 4-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + glucuronoxylan D-glucuronate = S-adenosyl-L-homocysteine + glucuronoxylan 4-O-methyl-D-glucuronate. GO:0015139 alpha-ketoglutarate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015139 Reactome:R-HSA-372480 2-oxoglutarate transporter activity Enables the transfer of alpha-ketoglutarate from one side of a membrane to the other. Alpha-ketoglutarate (or oxoglutarate) is a compound with important roles in carbohydrate and amino acid metabolism, especially in transamination reactions and as a component of the TCA cycle. CHEBI:134268 (S)-mandelamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134268 CHEBI:134269 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134269 GO:0015135 glucuronate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015135 Enables the transfer of glucuronate from one side of a membrane to the other. Glucuronate is the uronic acid formally derived from glucose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group. GO:0015136 sialic acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015136 Enables the transfer of sialic acid from one side of a membrane to the other. GO:0015137 citrate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015137 Reactome:R-HSA-433104|TC:2.A.29.7.2 tricarboxylate transport protein Enables the transfer of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, from one side of a membrane to the other. GO:0015138 fumarate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015138 dicarboxylate (succinate/fumarate/malate) antiporter activity Enables the transfer of fumarate from one side of a membrane to the other. Fumarate is a key intermediate in metabolism and is formed in the TCA cycle from succinate and converted into malate. GO:0015131 oxaloacetate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015131 Enables the transfer of oxaloacetate, the anion of oxobutanedioic acid, from one side of a membrane to the other. GO:0030772 tryptophan 2-C-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030772 MetaCyc:TRYPTOPHAN-2-C-METHYLTRANSFERASE-RXN|KEGG_REACTION:R08547|EC:2.1.1.106|RHEA:17321 S-adenosylmethionine:tryptophan 2-methyltransferase activity|S-adenosyl-L-methionine:L-tryptophan 2-C-methyltransferase activity|tryptophan 2-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine(1+) + L-tryptophan = S-adenosyl-L-homocysteine + L-2-methyltryptophan + H(+). GO:0015132 prostaglandin transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015132 Reactome:R-HSA-5661188|Reactome:R-HSA-879528 prostaglandin/thromboxane transporter activity Enables the transfer of prostaglandins from one side of a membrane to the other. A prostaglandin is any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities. GO:0030773 6-hydroxymellein O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030773 KEGG_REACTION:R03934|EC:2.1.1.108|RHEA:15201|MetaCyc:6-HYDROXYMELLEIN-O-METHYLTRANSFERASE-RXN 6-hydroxymellein methyltransferase activity|S-adenosyl-L-methionine:6-hydroxymellein 6-O-methyltransferase activity Catalysis of the reaction: 6-hydroxymellein + S-adenosyl-L-methionine = 6-methoxymellein + S-adenosyl-L-homocysteine + H(+). GO:0015133 uronic acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015133 Enables the transfer of uronic acid from one side of a membrane to the other. Uronic acids are any monocarboxylic acid formally derived by oxidizing to a carboxyl group the terminal hydroxymethylene group of either an aldose with four or more carbon atoms in the molecule, or of any glycoside derived from such an aldose. GO:0030770 demethylmacrocin O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030770 KEGG_REACTION:R02859|MetaCyc:DEMETHYLMACROCIN-O-METHYLTRANSFERASE-RXN|RHEA:17573|EC:2.1.1.102 demethylmacrocin methyltransferase activity|S-adenosyl-L-methionine:demethylmacrocin 2'''-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine(1+) + demethylmacrocin = S-adenosyl-L-homocysteine + H(+) + macrocin. GO:0015134 hexuronate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015134 hexuronide transmembrane transporter activity Enables the transfer of hexuronates from one side of a membrane to the other. A hexuronate is any monocarboxylic acid derived from a hexose by oxidation of C-6. GO:0030771 N-benzoyl-4-hydroxyanthranilate 4-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030771 RHEA:17405|MetaCyc:2.1.1.105-RXN|KEGG_REACTION:R04421|EC:2.1.1.105 S-adenosyl-L-methionine:N-benzoyl-4-O-hydroxyanthranilate 4-O-methyltransferase activity|N-benzoyl-4-hydroxyanthranilate 4-methyltransferase activity|benzoyl-CoA:anthranilate N-benzoyltransferase Catalysis of the reaction: N-benzoyl-4-hydroxyanthranilate + S-adenosyl-L-methionine(1+) = N-benzoyl-4-methoxyanthranilate + S-adenosyl-L-homocysteine + H(+). CHEBI:134262 L-arginyl-L-amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134262 GO:0015130 mevalonate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015130 monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity Enables the transfer of mevalonate from one side of a membrane to the other. Mevalonate is the anion of mevalonic acid; its (R)-enantiomer is a strategic intermediate derived from hydroxymethylglutaryl-CoA in the biosynthesis of polyprenyl compounds. GO:0030769 macrocin O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030769 MetaCyc:MACROCIN-O-METHYLTRANSFERASE-RXN|RHEA:17269|EC:2.1.1.101|KEGG_REACTION:R02858 S-adenosyl-L-methionine:macrocin 3'''-O-methyltransferase activity|S-adenosyl-L-methionine-macrocin O-methyltransferase activity|macrocin methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine(1+) + macrocin = S-adenosyl-L-homocysteine + H(+) + tylosin. GO:0030767 3-hydroxyanthranilate 4-C-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030767 EC:2.1.1.97|KEGG_REACTION:R02667|RHEA:17833|MetaCyc:2.1.1.97-RXN S-adenosyl-L-methionine:3-hydroxyanthranilate 4-C-methyltransferase activity|3-hydroxyanthranilate 4-methyltransferase activity Catalysis of the reaction: 3-hydroxyanthranilate + S-adenosyl-L-methionine = 3-hydroxy-4-methylanthranilate + S-adenosyl-L-homocysteine + H(+). GO:0030768 16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030768 EC:2.1.1.99|RHEA:11336|KEGG_REACTION:R04013|MetaCyc:2.1.1.99-RXN S-adenosyl-L-methionine:3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase activity|3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase activity|S-adenosyl-L-methionine:16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase activity|16-methoxy-2,3-dihydro-3-hydroxytabersonine methyltransferase activity|NMT activity Catalysis of the reaction: (3R)-3-hydroxy-16-methoxy-2,3-dihydrotabersonine + S-adenosyl-L-methionine = S-adenosyl-L-homocysteine + deacetoxyvindoline + H(+). GO:0030765 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030765 GO:0030766 11-O-demethyl-17-O-deacetylvindoline O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030766 EC:2.1.1.94|RHEA:20992|MetaCyc:2.1.1.94-RXN S-adenosyl-L-methionine:16-hydroxytabersonine 16-O-methyltransferase activity|S-adenosyl-L-methionine:11-O-demethyl-17-O-deacetylvindoline 11-O-methyltransferase activity|11-demethyl-17-deacetylvindoline 11-methyltransferase activity|tabersonine 16-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 11-O-demethyl-17-O-deacetylvindoline = S-adenosyl-L-homocysteine + 17-O-deacetylvindoline. GO:0030763 isobutyraldoxime O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030763 RHEA:10996|KEGG_REACTION:R04169|EC:2.1.1.91|MetaCyc:ISOBUTYRALDOXIME-O-METHYLTRANSFERASE-RXN S-adenosylmethionine:aldoxime O-methyltransferase activity|aldoxime methyltransferase activity|aldoxime O-methyltransferase activity|S-adenosyl-L-methionine:2-methylpropanal-oxime O-methyltransferase activity Catalysis of the reaction: 2-methylpropanal oxime + S-adenosyl-L-methionine = 2-methylpropanal O-methyloxime + S-adenosyl-L-homocysteine + H(+). GO:0030764 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030764 CHEBI:134278 S-adenosyl-S-carboxymethyl-L-homocysteine dizwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134278 GO:0015146 pentose transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015146 Enables the transfer of a pentose sugar from one side of a membrane to the other. Pentose is a monosaccharide with 5 carbon atoms. GO:0015147 L-arabinose transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015147 L-arabinose/beta-D-thiogalactopyranoside:hydrogen antiporter activity Enables the transfer of L-arabinose from one side of a membrane to the other. Arabinose occurs free, for example in the heartwood of many conifers and in the combined states, in both furanose and pyranose forms, as a constituent of various plant hemicelluloses, bacterial polysaccharides, etc. GO:0015148 D-xylose transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015148 Enables the transfer of D-xylose from one side of a membrane to the other. D-xylose (the naturally occurring enantiomer is always D-) is a constituent of plant polysaccharides. GO:0015149 hexose transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015149 Reactome:R-HSA-5638222|Reactome:R-HSA-189242 Enables the transfer of a hexose sugar, a monosaccharide with 6 carbon atoms, from one side of a membrane to the other. GO:0030761 8-hydroxyquercitin 8-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030761 KEGG_REACTION:R04398|MetaCyc:2.1.1.88-RXN|RHEA:16593|EC:2.1.1.88 8-hydroxyquercetin 8-O-methyltransferase activity|flavonol 8-methyltransferase activity|flavonol 8-O-methyltransferase activity|S-adenosyl-L-methionine:3,3',4',5,7,8-hexahydroxyflavone 8-O-methyltransferase activity Catalysis of the reaction: 3,3',4',5,7,8-hexahydroxyflavone + S-adenosyl-L-methionine(1+) = 3,3',4',5,7-pentahydroxy-8-methoxyflavone + S-adenosyl-L-homocysteine + H(+). GO:0015142 tricarboxylic acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015142 Reactome:R-HSA-372449|Reactome:R-HSA-75849 sodium:dicarboxylate/tricarboxylate symporter activity Enables the transfer of tricarboxylic acids from one side of a membrane to the other. Tricarboxylic acid are organic acids with three COOH groups. GO:0030762 tetrahydrocolumbamine 2-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030762 KEGG_REACTION:R04077|MetaCyc:2.1.1.89-RXN|EC:2.1.1.89|RHEA:22536 S-adenosyl-L-methionine:5,8,13,13a-tetrahydrocolumbamine 2-O-methyltransferase activity|tetrahydrocolumbamine methyltransferase activity Catalysis of the reaction: (S)-tetrahydrocolumbamine + S-adenosyl-L-methionine(1+) = S-adenosyl-L-homocysteine + H(+) + tetrahydropalmatine. GO:0015143 urate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015143 Reactome:R-HSA-2872497|Reactome:R-HSA-5625210|Reactome:R-HSA-561253 uric acid transmembrane transporter activity Enables the transfer of urate from one side of a membrane to the other. Urate is the anion of uric acid, 2,6,8-trioxypurine, the end product of purine metabolism in certain mammals and the main excretory product in uricotelic animals. GO:0015144 carbohydrate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015144 sugar transporter|carbohydrate transporter activity Enables the transfer of carbohydrate from one side of a membrane to the other. GO:0030760 pyridine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030760 KEGG_REACTION:R02862|Reactome:R-HSA-175987|MetaCyc:PYRIDINE-N-METHYLTRANSFERASE-RXN|RHEA:16893|EC:2.1.1.87 pyridine methyltransferase activity|S-adenosyl-L-methionine:pyridine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine(1+) + pyridine = N-methylpyridinium + S-adenosyl-L-homocysteine. GO:0015145 monosaccharide transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015145 Enables the transfer of a monosaccharide from one side of a membrane to the other. CHEBI:134275 keto-L-tagatose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134275 GO:0015140 malate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015140 dicarboxylate (succinate/fumarate/malate) antiporter activity Enables the transfer of malate from one side of a membrane to the other. Malate is a chiral hydroxydicarboxylic acid, hydroxybutanedioic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle. GO:0015141 succinate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015141 dicarboxylate (succinate/fumarate/malate) antiporter activity Enables the transfer of succinate, the dianion of ethane dicarboxylic acid, from one side of a membrane to the other. GO:0030758 3,7-dimethylquercitin 4'-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030758 MetaCyc:2.1.1.83-RXN|RHEA:21832|EC:2.1.1.83|KEGG_REACTION:R03456 S-adenosyl-L-methionine:3',4',5-trihydroxy-3,7-dimethoxyflavone 4'-O-methyltransferase activity|S-adenosyl-L-methionine:5,3',4'-trihydroxy-3,7-dimethoxyflavone 4'-O-methyltransferase activity|flavonol 4'-methyltransferase activity|flavonol 4'-O-methyltransferase activity|4'-OMT activity|3,7-dimethylquercetin 4'-O-methyltransferase activity Catalysis of the reaction: 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-methionine(1+) = 3',5-dihydroxy-3,4',7-trimethoxyflavone + S-adenosyl-L-homocysteine + H(+). GO:0030759 methylquercetagetin 6-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030759 MetaCyc:2.1.1.84-RXN|KEGG_REACTION:R04505|EC:2.1.1.84|RHEA:18717 flavonol 6-methyltransferase activity|S-adenosyl-L-methionine:3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone 6-O-methyltransferase activity|flavonol 6-O-methyltransferase activity|6-OMT Catalysis of the reaction: 3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone + S-adenosyl-L-methionine(1+) = 3',4',5-trihydroxy-3,6,7-trimethoxyflavone + S-adenosyl-L-homocysteine + H(+). GO:0030756 isoorientin 3'-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030756 RHEA:24096|MetaCyc:ISOORIENTIN-3-O-METHYLTRANSFERASE-RXN|EC:2.1.1.78|KEGG_REACTION:R03731 S-adenosyl-L-methionine:isoorientin 3'-O-methyltransferase activity|isoorientin 3'-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine(1+) + isoorientin = S-adenosyl-L-homocysteine + H(+) + isoscoparin. GO:0030757 3-methylquercitin 7-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030757 RHEA:16181|MetaCyc:2.1.1.82-RXN|EC:2.1.1.82|KEGG_REACTION:R05323 flavonol 7-O-methyltransferase activity|S-adenosyl-L-methionine:5,7,3',4'-tetrahydroxy-3-methoxyflavone 7-O-methyltransferase activity|S-adenosyl-L-methionine:3',4',5,7-tetrahydroxy-3-methoxyflavone 7-O-methyltransferase activity|7-OMT activity|3-methylquercetin 7-O-methyltransferase activity|flavonol 7-methyltransferase activity Catalysis of the reaction: 3',4',5,7-tetrahydroxy-3-methoxyflavone + S-adenosyl-L-methionine(1+) = 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-homocysteine. GO:0005798 Golgi-associated vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005798 NIF_Subcellular:sao819927218 Golgi vesicle|vesicular component Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell. GO:0030754 apigenin 4'-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030754 RHEA:20429|EC:2.1.1.75|MetaCyc:APIGENIN-4-O-METHYLTRANSFERASE-RXN S-adenosyl-L-methionine:5,7,4'-trihydroxyflavone 4'-O-methyltransferase activity|flavonoid methyltransferase activity|flavonoid O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 5,7,4'-trihydroxyflavone = S-adenosyl-L-homocysteine + 4'-methoxy-5,7-dihydroxyflavone. GO:0030755 quercetin 3-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030755 MetaCyc:QUERCETIN-3-O-METHYLTRANSFERASE-RXN|EC:2.1.1.76|RHEA:17673 flavonol 3-O-methyltransferase activity|flavonoid 3-methyltransferase activity|S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxy-flavone. GO:0005799 obsolete coatomer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005799 COPI vesicle|coatomer OBSOLETE. (Was not defined before being made obsolete). GO:0030752 5-hydroxyfuranocoumarin 5-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030752 RHEA:11808|EC:2.1.1.69|MetaCyc:2.1.1.69-RXN S-adenosyl-L-methionine:bergaptolO-methyltransferase activity|BMT activity|furanocoumarin 5-methyltransferase activity|furanocoumarin 5-O-methyltransferase activity|S-adenosyl-L-methionine:5-hydroxyfurocoumarin 5-O-methyltransferase activity|S-adenosyl-L-methionine:bergaptol O-methyltransferase activity|bergaptol methyltransferase activity|bergaptol O-methyltransferase activity|bergaptol 5-O-methyltransferase activity|S-adenosyl-L-methionine:5-hydroxyfuranocoumarin 5-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 5-hydroxyfuranocoumarin = S-adenosyl-L-homocysteine + 5-methoxyfuranocoumarin. GO:0005796 Golgi lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005796 The volume enclosed by the membranes of any cisterna or subcompartment of the Golgi apparatus, including the cis- and trans-Golgi networks. GO:0030753 8-hydroxyfuranocoumarin 8-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030753 EC:2.1.1.70|KEGG_REACTION:R02982 xanthotoxol O-methyltransferase activity|S-adenosyl-L-methionine:8-hydroxyfurocoumarin 8-O-methyltransferase activity|furanocoumarin 8-O-methyl-transferase activity|xanthotoxol 8-O-methyltransferase activity|XMT activity|S-adenosyl-L-methionine:8-hydroxyfuranocoumarin 8-O-methyltransferase activity|S-adenosyl-L-methionine:xanthotoxol O-methyltransferase activity|furanocoumarin 8-methyltransferase activity|xanthotoxol methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + xanthotoxol = S-adenosyl-L-homocysteine + xanthotoxin. Xanthotoxol is also known as 8-hydroxyfuranocoumarin and xanthotoxin as 8-methoxyfuranocoumarin. GO:0005797 Golgi medial cisterna biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005797 The middle Golgi cisterna (or cisternae). GO:0005794 Golgi apparatus biolink:CellularComponent go-plus goslim_chembl|goslim_mouse|goslim_yeast|goslim_candida|goslim_agr|goslim_pir|goslim_plant|goslim_drosophila|goslim_aspergillus|goslim_generic http://purl.obolibrary.org/obo/GO_0005794 NIF_Subcellular:sao451912436|Wikipedia:Golgi_apparatus Golgi complex|Golgi ribbon|Golgi A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. GO:0005795 Golgi stack biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005795 dictyosome|Golgi cisternae The set of thin, flattened membrane-bounded compartments, called cisternae, that form the central portion of the Golgi complex. The stack usually comprises cis, medial, and trans cisternae; the cis- and trans-Golgi networks are not considered part of the stack. GO:0005792 obsolete microsome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005792 Wikipedia:Microsome microsomal membrane|microsome OBSOLETE. Any of the small, heterogeneous, artifactual, vesicular particles, 50-150 nm in diameter, that are formed when some eukaryotic cells are homogenized and that sediment on centrifugation at 100000 g. GO:0005793 endoplasmic reticulum-Golgi intermediate compartment biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005793 Wikipedia:Vesicular-tubular_cluster ERGIC|vesicular-tubular cluster|endoplasmic reticulum-Golgi transport container|EGTC|ER-Golgi transport container|pre-Golgi intermediate compartment|ER-Golgi intermediate compartment|VTC A complex system of membrane-bounded compartments located between endoplasmic reticulum (ER) and the Golgi complex, with a distinctive membrane protein composition; involved in ER-to-Golgi and Golgi-to-ER transport. GO:0005790 smooth endoplasmic reticulum biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005790 NIF_Subcellular:sao710427438|Wikipedia:Endoplasmic_reticulum#Smooth_endoplasmic_reticulum SER|smooth ER The smooth endoplasmic reticulum (smooth ER or SER) has no ribosomes attached to it. The smooth ER is the recipient of the proteins synthesized in the rough ER. Those proteins to be exported are passed to the Golgi complex, the resident proteins are returned to the rough ER and the lysosomal proteins after phosphorylation of their mannose residues are passed to the lysosomes. Glycosylation of the glycoproteins also continues. The smooth ER is the site of synthesis of lipids, including the phospholipids. The membranes of the smooth ER also contain enzymes that catalyze a series of reactions to detoxify both lipid-soluble drugs and harmful products of metabolism. Large quantities of certain compounds such as phenobarbital cause an increase in the amount of the smooth ER. GO:0005791 rough endoplasmic reticulum biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005791 Wikipedia:Endoplasmic_reticulum#Rough_endoplasmic_reticulum|NIF_Subcellular:sao1881364067 rough ER|RER The rough (or granular) endoplasmic reticulum (ER) has ribosomes adhering to the outer surface; the ribosomes are the site of translation of the mRNA for those proteins which are either to be retained within the cisternae (ER-resident proteins), the proteins of the lysosomes, or the proteins destined for export from the cell. Glycoproteins undergo their initial glycosylation within the cisternae. GO:0015117 thiosulfate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015117 RHEA:32807 thiosulfate permease activity|thiosulphate transporter activity Enables the transfer of thiosulfate ions, S2O3(2-), from one side of a membrane to the other. CHEBI:134246 (R)-2-hydroxyglutaryl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134246 GO:0015118 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015118 CHEBI:134247 (11R)-11-hydroperoxylinoleic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134247 GO:0015119 hexose phosphate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015119 Enables the transfer of hexose phosphate from one side of a membrane to the other. Hexose phosphates is any of a group of monophosphorylated aldoses with a chain of six carbon atoms in the molecule. GO:0015113 nitrite transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015113 nitrite/nitrate porter activity Enables the transfer of nitrite (NO2-) ions from one side of a membrane to the other. GO:0015114 phosphate ion transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015114 RHEA:32823 phosphate transmembrane transporter activity Enables the transfer of phosphate (PO4 3-) ions from one side of a membrane to the other. GO:0015115 silicate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015115 Enables the transfer of silicates from one side of a membrane to the other. Silicates are the salts of silicic acids, and are usually composed of silicon and oxygen (Si[x]O[y]), one or more metals, and possibly hydrogen. Types of silicate include unisilicates, metasilicates and hydrous silicates. CHEBI:134248 (11R)-11-hydroperoxylinoleate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134248 GO:0015116 sulfate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015116 Reactome:R-HSA-8875871|Reactome:R-HSA-3560789|Reactome:R-HSA-427555|RHEA:34983 sulphate transporter activity|sulfate permease activity Enables the transfer of sulfate ions, SO4(2-), from one side of a membrane to the other. CHEBI:134249 alkanesulfonate oxoanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134249 GO:0030750 putrescine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030750 MetaCyc:PUTRESCINE-N-METHYLTRANSFERASE-RXN|EC:2.1.1.53|RHEA:15037|KEGG_REACTION:R01153 putrescine methyltransferase activity|S-adenosyl-L-methionine:putrescine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + putrescine = N-methylputrescine + S-adenosyl-L-homocysteine + H(+). GO:0015110 cyanate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015110 Enables the transfer of cyanate, NCO-, the anion of cyanic acid, from one side of a membrane to the other. GO:0030751 licodione 2'-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030751 EC:2.1.1.65|KEGG_REACTION:R03623|RHEA:18521|MetaCyc:LICODIONE-2-O-METHYLTRANSFERASE-RXN S-adenosyl-L-methionine:licodione 2'-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine(1+) + licodione = 2'-O-methyllicodione + S-adenosyl-L-homocysteine + H(+). GO:0015111 iodide transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015111 Reactome:R-HSA-209910|Reactome:R-HSA-5627870|Reactome:R-HSA-5627802 Enables the transfer of iodide ions from one side of a membrane to the other. GO:0015112 nitrate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015112 nitrite/nitrate porter activity Enables the transfer of nitrate ions (NO3-) from one side of a membrane to the other. CHEBI:134243 phosphatidylethanolamine 40:5 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134243 CHEBI:134241 phosphatidylethanolamine 40:6 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134241 GO:0030747 indolepyruvate C-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030747 EC:2.1.1.47|MetaCyc:INDOLEPYRUVATE-C-METHYLTRANSFERASE-RXN|RHEA:12112 S-adenosyl-L-methionine:indolepyruvate C-methyltransferase activity|indolepyruvate methyltransferase activity|indolepyruvate 3-methyltransferase activity|indolepyruvic acid methyltransferase activity|S-adenosyl-L-methionine:(indol-3-yl)pyruvate C-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + (indol-3-yl)pyruvate = S-adenosyl-L-homocysteine + (S)-3-(indol-3-yl)-2-oxobutanoate. GO:0030748 amine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030748 MetaCyc:AMINE-N-METHYLTRANSFERASE-RXN|EC:2.1.1.49 arylamine N-methyltransferase activity|nicotine N-methyltransferase activity|tryptamine N-methyltransferase activity|S-adenosyl-L-methionine:amine N-methyltransferase activity|tryptamine methyltransferase Catalysis of the reaction: S-adenosyl-L-methionine + an amine = S-adenosyl-L-homocysteine + a methylated amine. GO:0030745 dimethylhistidine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030745 EC:2.1.1.44|KEGG_REACTION:R04436|RHEA:11104|MetaCyc:2.1.1.44-RXN S-adenosyl-L-methionine:alpha-N,alpha-N-dimethyl-L-histidine alpha-N-methyltransferase activity|histidine-alpha-N-methyltransferase activity|dimethylhistidine methyltransferase activity|S-adenosyl-L-methionine:Nalpha,Nalpha-dimethyl-L-histidine nalpha-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + N-alpha,N-alpha-dimethyl-L-histidine = S-adenosyl-L-homocysteine + N-alpha,N-alpha,N-alpha-trimethyl-L-histidine. GO:0030746 isoflavone 4'-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030746 EC:2.1.1.46|MetaCyc:ISOFLAVONE-4-O-METHYLTRANSFERASE-RXN|RHEA:31739 4'-hydroxyisoflavone methyltransferase activity|S-adenosyl-L-methionine:isoflavone 4'-O-methyltransferase activity|isoflavone methyltransferase activity|isoflavone O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + isoflavone = S-adenosyl-L-homocysteine + 4'-O-methylisoflavone. GO:0030743 rRNA (adenosine-2'-O-)-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030743 RHEA:43212|MetaCyc:2.1.1.66-RXN|EC:2.1.1.230 S-adenosyl-L-methionine:rRNA (adenosine-2'-O)-methyltransferase activity|ribosomal ribonucleate adenosine 2'-methyltransferase activity|rRNA adenosine 2'-methylase activity|thiostrepton-resistance methylase activity|RNA-pentose methylase activity Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing a single residue of 2'-O-methyladenosine. GO:0030744 luteolin O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030744 EC:2.1.1.42|RHEA:14589|KEGG_REACTION:R03587|MetaCyc:LUTEOLIN-O-METHYLTRANSFERASE-RXN S-adenosyl-L-methionine:5,7,3',4'-tetrahydroxyflavone 3'-O-methyltransferase activity|S-adenosylmethionine:flavone/flavonol 3'-O-methyltransferase activity|o-dihydric phenol meta-O-methyltransferase activity|luteolin methyltransferase activity|o-dihydric phenol methyltransferase activity|o-diphenol m-O-methyltransferase activity|luteolin 3'-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + luteolin = 4',5,7-trihydroxy-3'-methoxyflavone + S-adenosyl-L-homocysteine + H(+). GO:0030741 inositol 1-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030741 EC:2.1.1.40|MetaCyc:MYO-INOSITOL-3-O-METHYLTRANSFERASE-RXN|KEGG_REACTION:R01188|RHEA:17565 inositol 3-O-methyltransferase (name based on 1L-numbering system and not 1D-numbering)|S-adenosyl-L-methionine:1D-myo-inositol 1-O-methyltransferase activity|inositol 3-O-methyltransferase activity|S-adenosylmethionine:myo-inositol 3-methyltransferase activity|myo-inositol 3-O-methyltransferase activity|S-adenosyl-L-methionine:myo-inositol 3-O-methyltransferase activity|inositol D-1-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine(1+) + myo-inositol = 1D-1-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H(+). GO:0030742 GTP-dependent protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030742 Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) when at least one of the interacting partners is in the GTP-bound state. GO:0030749 loganate O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030749 RHEA:12508|EC:2.1.1.50|MetaCyc:LOGANATE-O-METHYLTRANSFERASE-RXN S-adenosyl-L-methionine:loganate 11-O-methyltransferase activity|S-adenosyl-L-methionine:loganic acid methyltransferase activity|loganate methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + loganate = S-adenosyl-L-homocysteine + loganin. CHEBI:134257 lipid A(4-) (E. coli) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134257 GO:0015128 gluconate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015128 L-idonate/D-gluconate:hydrogen symporter activity Enables the transfer of gluconate from one side of a membrane to the other. Gluconate is the aldonic acid derived from glucose. GO:0015129 lactate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015129 Reactome:R-HSA-373867|Reactome:R-HSA-373875 monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity Enables the transfer of lactate from one side of a membrane to the other. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices. CHEBI:134258 beta-L-Ara4N-lipid A (E. coli) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134258 CHEBI:134256 lipid A (E. coli) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134256 GO:0015124 allantoate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015124 Enables the transfer of allantoate from one side of a membrane to the other. Allantoate is the end product of purine metabolism in mammals and some fish, formed form allantoin. It is widely distributed in plants as an important source of stored nitrogen. GO:0015125 bile acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015125 Reactome:R-HSA-194130|Reactome:R-HSA-5661198|Reactome:R-HSA-194079|Reactome:R-HSA-194083|Reactome:R-HSA-5661184 Enables the transfer of bile acid from one side of a membrane to the other. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine. GO:0015126 canalicular bile acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015126 The directed movement of bile acid and bile salts out of a hepatocyte and into the bile canaliculus by means of an agent such as a transporter or pore. Bile canaliculi are the thin tubes formed by hepatocyte membranes. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine. CHEBI:134259 beta-L-Ara4N-lipid A(2-) (E. coli) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134259 GO:0015127 bilirubin transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015127 Reactome:R-HSA-5679041|Reactome:R-HSA-9661417|Reactome:R-HSA-5679031 Enables the transfer of bilirubin from one side of a membrane to the other. Bilirubin is a linear tetrapyrrole produced in the reticuloendothelial system from biliverdin and transported to the liver as a complex with serum albumin. In the liver, bilirubin is converted to bilirubin bisglucuronide, which is excreted in the bile. GO:0015120 phosphoglycerate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015120 Enables the transfer of phosphoglycerates from one side of a membrane to the other. Phosphoglycerates are important intermediates in glycolysis and 3-phosphoglycerate is a precursor in serine biosynthesis. GO:0015121 phosphoenolpyruvate:phosphate antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015121 phosphoenolpyruvate/phosphate translocator|PPT Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phosphoenolpyruvate(out) + phosphate(in) = phosphoenolpyruvate(in) + phosphate(out). GO:0030740 inositol 3-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030740 KEGG_REACTION:R01189|MetaCyc:MYO-INOSITOL-1-O-METHYLTRANSFERASE-RXN|RHEA:18877|EC:2.1.1.39 inositol L-1-methyltransferase activity|S-adenosyl-L-methionine:1D-myo-inositol 3-O-methyltransferase activity|S-adenosylmethionine:myo-inositol 1-methyltransferase activity|myo-inositol 1-O-methyltransferase (name based on 1L-numbering system and not 1D-numbering)|myo-inositol 1-methyltransferase activity|myo-inositol 1-O-methyltransferase activity|S-adenosyl-L-methionine:myo-inositol 1-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine(1+) + myo-inositol = 1D-3-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H(+). GO:0015122 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015122 GO:0015123 acetate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015123 Enables the transfer of acetate from one side of a membrane to the other. Acetate is the 2-carbon carboxylic acid ethanoic acid. CHEBI:134251 guaiacols biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134251 GO:0030736 phenol O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030736 RHEA:14809|EC:2.1.1.25|KEGG_REACTION:R01239|MetaCyc:PHENOL-O-METHYLTRANSFERASE-RXN S-adenosyl-L-methionine:phenol O-methyltransferase activity|PMT Catalysis of the reaction: S-adenosyl-L-methionine + phenol = S-adenosyl-L-homocysteine + anisole + H(+). PO:0000045 embryo root biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000045 embryonic root (exact)|初期の根、胚根 (Japanese, exact)|raíz embriónica (Spanish, exact) A root (PO:0009005) that is initiated in a developing plant embryo (PO:0009009). GO:0030737 iodophenol O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030737 MetaCyc:IODOPHENOL-O-METHYLTRANSFERASE-RXN|EC:2.1.1.26|KEGG_REACTION:R03746|RHEA:14313 S-adenosyl-L-methionine:2-iodophenol O-methyltransferase activity Catalysis of the reaction: 2-iodophenol + S-adenosyl-L-methionine = 1-iodo-2-methoxybenzene + S-adenosyl-L-homocysteine + H(+). GO:0005778 peroxisomal membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005778 peroxisome membrane The lipid bilayer surrounding a peroxisome. GO:0030734 polysaccharide O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030734 EC:2.1.1.18|MetaCyc:POLYSACCHARIDE-O-METHYLTRANSFERASE-RXN S-adenosyl-L-methionine:1,4-alpha-D-glucan 6-O-methyltransferase activity|polysaccharide methyltransferase activity|acylpolysacharide 6-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 1,4-N1-D-glucooligosaccharide = S-adenosyl-L-homocysteine + oligosaccharide containing 6-methyl-D-glucose units. GO:0030735 carnosine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030735 Reactome:R-HSA-8876789|EC:2.1.1.22|RHEA:14205|KEGG_REACTION:R02144|MetaCyc:CARNOSINE-N-METHYLTRANSFERASE-RXN S-adenosyl-L-methionine:carnosine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + carnosine = S-adenosyl-L-homocysteine + anserine + H(+). GO:0005779 integral component of peroxisomal membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005779 integral to peroxisomal membrane The component of the peroxisomal membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0030732 methionine S-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030732 EC:2.1.1.12|MetaCyc:METHIONINE-S-METHYLTRANSFERASE-RXN|RHEA:13761 S-adenosylmethionine transmethylase activity|methionine methyltransferase activity|S-adenosyl methionine:methionine methyl transferase activity|S-adenosylmethionine-methionine methyltransferase activity|S-adenosyl-L-methionine:L-methionine S-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + L-methionine = S-adenosyl-L-homocysteine + S-methyl-L-methionine. GO:0005776 autophagosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005776 NIF_Subcellular:sao8663416959 autophagic vacuole|initial autophagic vacuole A double-membrane-bounded compartment that engulfs endogenous cellular material as well as invading microorganisms to target them to the lytic vacuole/lysosome for degradation as part of macroautophagy. GO:0030733 fatty acid O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030733 MetaCyc:FATTY-ACID-O-METHYLTRANSFERASE-RXN|EC:2.1.1.15|RHEA:23012 fatty acid methyltransferase activity|fatty-acid O-methyltransferase activity|S-adenosyl-L-methionine:fatty-acid O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + a fatty acid = S-adenosyl-L-homocysteine + a fatty acid methyl ester. GO:0005777 peroxisome biolink:CellularComponent go-plus goslim_chembl|goslim_candida|goslim_yeast|goslim_plant|goslim_drosophila|goslim_aspergillus|goslim_generic http://purl.obolibrary.org/obo/GO_0005777 Wikipedia:Peroxisome|NIF_Subcellular:sao499555322 peroxisomal|peroxisome vesicle A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism. GO:0030730 sequestering of triglyceride biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030730 triglyceride sequestering|triglyceride retention|sequestration of triglyceride|triglyceride storage|sequestration of triacylglycerol|triacylglycerol retention|triglyceride sequestration|storage of triacylglycerol|triacylglycerol storage|retention of triacylglycerol|triacylglycerol sequestration|triacylglycerol sequestering|sequestering of triacylglycerol|retention of triglyceride|storage of triglyceride The process of binding or confining any triester of glycerol such that it is separated from other components of a biological system. GO:0005774 vacuolar membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005774 The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell. GO:0030731 guanidinoacetate N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030731 EC:2.1.1.2|MetaCyc:GUANIDINOACETATE-N-METHYLTRANSFERASE-RXN|RHEA:10656|KEGG_REACTION:R01883 guanidinoacetate methyltransferase activity|methionine-guanidinoacetic transmethylase activity|S-adenosyl-L-methionine:N-guanidinoacetate methyltransferase activity|guanidinoacetate transmethylase activity|GA methylpherase activity|guanidoacetate methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + guanidinoacetate = S-adenosyl-L-homocysteine + creatine + H(+). GO:0005775 vacuolar lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005775 The volume enclosed within the vacuolar membrane. GO:0005772 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005772 GO:0005773 vacuole biolink:CellularComponent go-plus goslim_flybase_ribbon|goslim_chembl|goslim_mouse|goslim_agr|goslim_yeast|goslim_candida|goslim_pir|goslim_plant|goslim_drosophila|goslim_aspergillus|goslim_generic http://purl.obolibrary.org/obo/GO_0005773 Wikipedia:Vacuole vacuolar carboxypeptidase Y A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol. GO:0005770 late endosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005770 NIF_Subcellular:nlx_subcell_20090702 PVC|prevacuolar compartment A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center. GO:0005771 multivesicular body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005771 NIF_Subcellular:sao2045955158 MVB|MVE|multivesicular endosome A type of endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm. GO:0030738 tyramine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030738 KEGG_REACTION:R02384|EC:2.1.1.27|MetaCyc:TYRAMINE-N-METHYLTRANSFERASE-RXN|RHEA:14865 DIB O-methyltransferase (3,5-diiodo-4-hydroxy-benzoic acid)|S-adenosyl-L-methionine:tyramine N-methyltransferase activity|tyramine methylpherase activity|S-adenosyl-methionine:tyramine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tyramine = N-methyltyramine + S-adenosyl-L-homocysteine + H(+). GO:0030739 O-demethylpuromycin O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030739 MetaCyc:2.1.1.38-RXN|RHEA:22280|EC:2.1.1.38 S-adenosyl-L-methionine:O-demethylpuromycin O-methyltransferase activity|O-demethylpuromycin methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + O-demethylpuromycin = S-adenosyl-L-homocysteine + puromycin. CHEBI:134225 1,4-benzosemiquinones biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134225 PO:0000033 fruit valve biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000033 果実の弁 (Japanese, exact)|valva de fruto (Spanish, exact) A valve that is a part of a fruit that splits apart when the fruit dehisces. GO:0030725 germline ring canal formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030725 ring canal formation Assembly of the cytoplasmic bridges between developing spermatogonial or oogonial cysts. GO:0030726 male germline ring canal formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030726 testicular ring canal formation|spermatocyte ring canal formation Formation of the intercellular bridges that connect the germ-line cells of a male cyst. GO:0030723 ovarian fusome organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030723 ovarian fusome organisation|ovarian fusome organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome of ovarian cells, an organelle derived from the spectrosome. It anchors the mitotic spindle pole to provide orientation during cystoblast cell divisions. GO:0005789 endoplasmic reticulum membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005789 ER membrane The lipid bilayer surrounding the endoplasmic reticulum. GO:0030724 testicular fusome organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030724 testicular fusome organisation|testicular fusome organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome of testicular cells, an organelle derived from the spectrosome. GO:0030721 spectrosome organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030721 spectrosome organization and biogenesis|spectrosome organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spectrosome, a germline specific spherical organelle that is the precursor to the fusome. CHEBI:148869 alpha-D-galactosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_148869 GO:0005787 signal peptidase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005787 A protein complex that is located in the endoplasmic reticulum membrane and cleaves the signal sequence from precursor proteins following their transport out of the cytoplasmic space. PO:0000037 shoot axis apex biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000037 ápice del epiblasto (epiblastema) (Spanish, exact)|シュート頂、茎頂 (Japanese, exact) A shoot axis (PO:0025029) that is the most distal part of a shoot system (PO:0009006) and has as parts a shoot apical meristem (PO:0020148) and the youngest primordia (PO:0025127). PO:0000038 primary endosperm cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000038 célula primaria del endosperma (Spanish, exact)|一次胚乳細胞 (Japanese, exact) Cell produced by the fusion of sperm cell nucleus and two polar nuclei of the central cell (or diploid secondary endosperm nucleus, in cases where two polar nuclei fuse together before double fertilization). The first cell of the endosperm, often triploid. GO:0005788 endoplasmic reticulum lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005788 ER cisterna|ER lumen|endoplasmic reticulum cisterna|cisternal lumen The volume enclosed by the membranes of the endoplasmic reticulum. GO:0030722 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030722 GO:0005785 signal recognition particle receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005785 docking protein complex|SR complex A transmembrane heterodimeric protein located in the membrane of the rough endoplasmic reticulum. Both subunits contain GTPase domains with which signal recognition particle interacts. In the presence of GTP and SRP receptor, SRP is released from the ribosome-nascent chain complex. GO:0030720 oocyte localization involved in germarium-derived egg chamber formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030720 oogenesis, oocyte localization|oocyte localization during oogenesis|establishment and maintenance of oocyte position during oogenesis|oocyte localization during germarium-derived egg chamber formation|oocyte localisation involved in germarium-derived egg chamber formation|oocyte positioning during oogenesis|oogenesis, establishment and maintenance of oocyte localization|establishment and maintenance of oocyte localization in egg chamber Directed movement of the oocyte, following its specification, from its original central position in the cyst to a posterior position relative to the nurse cells of the egg chamber, and its maintenance in this posterior location. This is the first sign of anterior-posterior asymmetry in the developing egg chamber. GO:0005786 signal recognition particle, endoplasmic reticulum targeting biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005786 Wikipedia:Signal_recognition_particle signal sequence receptor complex|SRP A ribonucleoprotein particle of 325 kDa composed of a 7S (300 nucleotide) RNA molecule and a complex of six different polypeptides. This binds both to the N-terminal signal peptide for proteins destined for the endoplasmic reticulum as they emerge from the large ribosomal subunit and also to the ribosome. This binding arrests further translation thereby preventing the proteins from being released into the cytosol. The SRP-ribosome complex then diffuses to the endoplasmic reticulum where it is bound to the signal recognition particle receptor, which allows resumption of protein synthesis and facilitates the passage of the growing polypeptide chain through the translocon. Through a process involving GTP hydrolysis, the SRP-SRP receptor complex dissociates and SRP returns to the cytosol. Of the six polypeptides of SRP the 54 kDa subunit (SRP54) is the central player. It contains an N-terminal GTPase domain and a C-terminal domain that binds directly to the signal peptide and the SRP RNA. Examples of this component are found in Mus musculus, Saccharomyces cerevisiae and Arabidopsis thaliana. GO:0005783 endoplasmic reticulum biolink:CellularComponent go-plus goslim_pir|goslim_plant|goslim_drosophila|goslim_aspergillus|goslim_generic|goslim_chembl|goslim_mouse|goslim_yeast|goslim_candida|goslim_agr http://purl.obolibrary.org/obo/GO_0005783 NIF_Subcellular:sao1036339110|Wikipedia:Endoplasmic_reticulum ER The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). GO:0005784 Sec61 translocon complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005784 Sec61p-Sbh1p-Sss1p complex A translocon complex that contains a core heterotrimer of conserved alpha, beta and gamma subunits, and may contain additional proteins (translocon-associated proteins or TRAPs); in budding yeast the core proteins are Sec61p, Sbh1p, and Sss1p. The Sec61 translocon complex functions in cotranslational and posttranslational translocation events. GO:0005781 obsolete peroxisome targeting signal receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005781 peroxisome targeting signal receptor complex OBSOLETE. (Was not defined before being made obsolete). GO:0005782 peroxisomal matrix biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005782 peroxisomal lumen The volume contained within the membranes of a peroxisome; in many cells the matrix contains a crystalloid core largely composed of urate oxidase. GO:0030729 acetoacetate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030729 Reactome:R-HSA-5694494|EC:6.2.1.16|MetaCyc:ACETOACETATE--COA-LIGASE-RXN|KEGG_REACTION:R01357|RHEA:16117 acetoacetyl-CoA synthetase activity|acetoacetate:CoA ligase (AMP-forming) Catalysis of the reaction: acetoacetate + ATP + CoA = acetoacetyl-CoA + AMP + diphosphate + H(+). GO:0005780 extrinsic component of intraperoxisomal membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005780 intra-peroxisomal peripheral membrane|extrinsic to intraperoxisomal membrane The component of the intraperoxisomal membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:0030727 germarium-derived female germ-line cyst formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030727 germarium-derived female germline cyst formation Formation, in a germarium, of a group of interconnected cells derived from a single female gonial founder cell (a cystoblast). The germarium is the most anterior portion of an insect ovariole. An example of this process is found in Drosophila melanogaster. GO:0030728 ovulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030728 Wikipedia:Ovulation The release of a mature ovum/oocyte from an ovary. GO:0015106 bicarbonate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015106 Reactome:R-HSA-2752067|RHEA:28695 Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-. GO:0015107 chlorate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015107 Enables the transfer of chlorate, ClO3-, from one side of a membrane to the other. CHEBI:134236 phosphatidic acid (16:0/18:1) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134236 GO:0015108 chloride transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015108 Reactome:R-HSA-5678822|Reactome:R-HSA-5678992|RHEA:29823|Reactome:R-HSA-5678863 chloride ion transmembrane transporter activity Enables the transfer of chloride ions from one side of a membrane to the other. CHEBI:134233 (4S)-4,16-dihydroxyretinoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134233 GO:0015109 chromate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015109 RHEA:32819 Enables the transfer of chromate from one side of a membrane to the other. Chromate is the anion of chromic acid, H2CrO4 (aq) or CrO3. GO:0015103 inorganic anion transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015103 Enables the transfer of inorganic anions from one side of a membrane to the other. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage. GO:0015104 antimonite transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015104 Enables the transfer of antimonite from one side of a membrane to the other. CHEBI:134237 phosphatidic acid 36:2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134237 GO:0015105 arsenite transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015105 Enables the transfer of arsenite from one side of a membrane to the other. GO:0015100 vanadium ion transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015100 Enables the transfer of vanadium (V) ions from one side of a membrane to the other. GO:0015101 organic cation transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015101 Reactome:R-HSA-561072|Reactome:R-HSA-549304|Reactome:R-HSA-549322|Reactome:R-HSA-561054|Reactome:R-HSA-549279|Reactome:R-HSA-2161500|Reactome:R-HSA-549129 Enables the transfer of organic cations from one side of a membrane to the other. Organic cations are atoms or small molecules with a positive charge that contain carbon in covalent linkage. PO:0000042 shoot-borne root biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000042 climbing root (broad)|stilt root (narrow)|シュート細胞由来の根 (Japanese, exact)|aerial root (narrow)|epiblasto (epiblastema) que se origina en la raíz (Spanish, exact)|adventitious root (broad) A root (PO:0009005) that develops from shoot axis (PO:0025029) tissue. GO:0030714 anterior/posterior axis specification, follicular epithelium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030714 anterior/posterior axis determination, follicular epithelium Polarization of the follicle cells of an insect ovary along the anterior/posterior axis. GO:0005758 mitochondrial intermembrane space biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005758 NIF_Subcellular:sao118944228 mitochondrial envelope lumen|mitochondrial membrane lumen The region between the inner and outer lipid bilayers of the mitochondrial envelope. GO:0005759 mitochondrial matrix biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005759 Wikipedia:Mitochondrial_matrix|NIF_Subcellular:sao1804523077 mitochondrial lumen|mitochondrial stroma The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation. GO:0030715 oocyte growth in germarium-derived egg chamber biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030715 The increase in volume of an oocyte during the growth phase of the egg chamber, once the egg chamber has left the germarium. An example of this process is found in Drosophila melanogaster. GO:0030712 negative regulation of border follicle cell delamination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030712 down-regulation of border follicle cell delamination|inhibition of border follicle cell delamination|negative regulation of border cell delamination|down regulation of border follicle cell delamination|downregulation of border follicle cell delamination Any process that decreases the frequency, rate or extent of border cell delamination. GO:0005756 mitochondrial proton-transporting ATP synthase, central stalk biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005756 One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the mitochondrial membrane-associated F0 proteins; rotates within the catalytic core during catalysis. GO:0005757 mitochondrial permeability transition pore complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005757 PTPC|MPTP complex|mitochondrial PT pore complex A protein complex that connects the inner and outer membranes of animal mitochondria and acts as a pore that can open transiently to allow free diffusion of solutes between the mitochondrial matrix and the cytosol. The pore complex is formed of the voltage-dependent anion channel (VDAC), the adenine nucleotide translocase (ANT) and cyclophilin-D (CyP-D). PO:0000025 root tip biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000025 根端 (Japanese, exact)|punta de la raíz (Spanish, exact) A cardinal organ part (PO:0025001) which is the apical portion of the root (PO:0009005), and includes the root apical meristem (PO:0020147) and root cap (PO:0020123). GO:0030713 ovarian follicle cell stalk formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030713 Development of ovarian follicle cells to create the interfollicular stalks that connect the egg chambers of progressive developmental stages. An example of this process is found in Drosophila melanogaster. GO:0030710 regulation of border follicle cell delamination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030710 regulation of border cell delamination Any process that regulates the frequency, rate or extent of border cell delamination. GO:0005754 mitochondrial proton-transporting ATP synthase, catalytic core biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005754 The hexamer, comprising three alpha and three beta subunits, that possesses the catalytic activity of the mitochondrial hydrogen-transporting ATP synthase. GO:0005755 obsolete hydrogen-transporting ATP synthase, coupling factor CF(0) biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005755 hydrogen-transporting ATP synthase, coupling factor CF(0) OBSOLETE. (Was not defined before being made obsolete). GO:0030711 positive regulation of border follicle cell delamination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030711 up-regulation of border follicle cell delamination|upregulation of border follicle cell delamination|positive regulation of border cell delamination|up regulation of border follicle cell delamination|activation of border follicle cell delamination|stimulation of border follicle cell delamination Any process that increases the frequency, rate or extent of border cell delamination. GO:0005752 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005752 GO:0005753 mitochondrial proton-transporting ATP synthase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005753 mitochondrial respiratory chain complex V A proton-transporting ATP synthase complex found in the mitochondrial membrane. GO:0005750 mitochondrial respiratory chain complex III biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005750 mitochondrial coenzyme Q-cytochrome c oxidoreductase complex|mitochondrial ubiquinol-cytochrome c oxidoreductase complex|mitochondrial electron transport complex III|mitochondrial coenzyme Q-cytochrome c reductase complex|mitochondrial ubiquinol-cytochrome-c reductase complex|mitochondrial cytochrome bc(1) complex|mitochondrial complex III|mitochondrial cytochrome bc1 complex A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains about 10 polypeptide subunits including four redox centers: cytochrome b/b6, cytochrome c1 and an 2Fe-2S cluster. Catalyzes the oxidation of ubiquinol by oxidized cytochrome c1. GO:0005751 mitochondrial respiratory chain complex IV biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005751 A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2). CHEBI:134208 N-acetyl-alpha-D-glucosaminyl-L-tyrosyl residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134208 CHEBI:134209 aporphine alkaloid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134209 GO:0030718 germ-line stem cell population maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030718 Any process by which an organism or tissue maintains a population of germ-line stem cells. GO:0030719 P granule organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030719 polar granule organisation|P granule organization and biogenesis|polar granule organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of polar granules, cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes. GO:0030716 oocyte fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030716 oocyte cell fate determination The process in which a cell becomes capable of differentiating autonomously into an oocyte cell regardless of its environment; upon determination, the cell fate cannot be reversed. GO:0030717 oocyte karyosome formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030717 The chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome. CHEBI:134206 2-methylserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134206 CHEBI:134207 methylcytosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134207 CHEBI:134205 2-methyl-D-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134205 PO:0000030 septum biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000030 septa (exact, plural)|隔壁 (Japanese, exact)|dissepiment (broad)|septo (Spanish, exact) A collective organ part structure composed of two or more layers of various tissues that is a partition that divides a cavity formed by the fusion of two or more organs. GO:0005769 early endosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005769 NIF_Subcellular:nlx_subcell_20090701 A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways. GO:0030703 eggshell formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030703 Construction of the eggshell, a product of the somatic follicle cell epithelium and a structure that supports the egg in a hostile environment, minimizing water loss whilst allowing gas exchanges essential for embryonic respiration. GO:0030704 vitelline membrane formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030704 Construction of the vitelline membrane portion of the egg shell, a rigid structure required to maintain the shape of the egg. GO:0030701 NAD+-dinitrogen-reductase ADP-D-ribosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030701 EC:2.4.2.37|MetaCyc:2.4.2.37-RXN|RHEA:18077 NAD--azoferredoxin (ADP-ribose)transferase activity|NAD-azoferredoxin (ADPribose)transferase activity|NAD-dinitrogen-reductase ADP-D-ribosyltransferase activity|NAD+:[dinitrogen reductase] (ADP-D-ribosyl)transferase activity|ADP-ribosyltransferase activity Catalysis of the reaction: NAD+ + [dinitrogen reductase] = nicotinamide + ADP-D-ribosyl-[dinitrogen reductase]. GO:0005767 secondary lysosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005767 NIF_Subcellular:sao1549842807 Vacuole formed by the fusion of a lysosome with an organelle (autosome) or with a primary phagosome. GO:0005768 endosome biolink:CellularComponent go-plus goslim_agr|goslim_pir|goslim_plant|goslim_drosophila|goslim_generic|goslim_chembl|goslim_mouse http://purl.obolibrary.org/obo/GO_0005768 Wikipedia:Endosome|NIF_Subcellular:sao1720343330 A vacuole to which materials ingested by endocytosis are delivered. GO:0030702 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030702 PO:0000015 cotyledon primordium biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000015 primordio de cotiledón (Spanish, exact)|cotyledon primordia (exact, plural)|portion of cotyledon primordium tissue (exact)|子葉原基（可視的）(Japanese, exact) A phyllome primordium (PO:0025128) that develops from a cotyledon anlagen (PO:0025432) and is part of a vegetative shoot apex (PO:0025223) and is committed to the development of a cotyledon (PO:0020030). GO:0005765 lysosomal membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005765 lysosome membrane The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm. PO:0000016 lateral root primordium biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000016 portion of lateral root primordium tissue (exact)|primordio de raíz lateral (Spanish, exact)|側根原基 (Japanese, exact) A root primordium (PO:0005029) that is part of a root (PO:0009005) and is committed to the development of a lateral root (PO:0020121). GO:0030700 glycine reductase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030700 Complex that possesses glycine reductase activity; usually comprises three subunits, of which two are selenoproteins; the subunits are typically designated selenoprotein A, selenoprotein B and protein C. GO:0005766 primary lysosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005766 NIF_Subcellular:sao1140587416 A lysosome before it has fused with a vesicle or vacuole. GO:0005763 mitochondrial small ribosomal subunit biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005763 mitochondrial ribosomal SSU complex|mitochondrial ribosomal small subunit complex|28S ribosomal subunit, mitochondrial The smaller of the two subunits of a mitochondrial ribosome. PO:0000017 vascular leaf primordium biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000017 primordio de hoja (Spanish, exact)|vascular leaf primordia (exact, plural)|portion of vascular leaf primordium tissue (exact)|葉原基 (Japanese, exact)|leaf primordium (exact) A phyllome primordium (PO:0025128) that develops from a vascular leaf anlagen (PO:0025431) and is part of a vegetative shoot apex (PO:0025223) and is committed to the development of a vascular leaf (PO:0009025). GO:0005764 lysosome biolink:CellularComponent go-plus goslim_plant|goslim_generic|goslim_chembl http://purl.obolibrary.org/obo/GO_0005764 Wikipedia:Lysosome|NIF_Subcellular:sao585356902 A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions. PO:0000018 ovule primordium biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000018 胚珠原基（可視的） (Japanese, exact)|portion of ovule primordium tissue (exact)|primordio de óvulo (Spanish, exact) A floral structure primordium (PO:0025477) that is committed to the development of an ovule (PO:0020003). PO:0000019 gynoecium primordium biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000019 雌蕊原基(可視的） (Japanese, exact)|portion of gynoecium primordium tissue (exact)|pistil primordium (exact)|primordio de gineceo (Spanish, exact) A floral structure primordium (PO:0025477) that is committed to the development of a gynoecium (PO:0009062). GO:0005761 mitochondrial ribosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005761 55S ribosome, mitochondrial A ribosome found in the mitochondrion of a eukaryotic cell; contains a characteristic set of proteins distinct from those of cytosolic ribosomes. GO:0005762 mitochondrial large ribosomal subunit biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005762 39S ribosomal subunit, mitochondrial The larger of the two subunits of a mitochondrial ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site). GO:0030709 border follicle cell delamination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030709 border cell delamination The delamination process that results in the splitting off of border cells from the anterior epithelium, prior to border cell migration. CHEBI:134219 decenals biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134219 GO:0005760 gamma DNA polymerase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005760 A DNA polymerase complex consisting of a large subunit, responsible for the catalytic activities, and a small accessory subunit. Functions in the replication and repair of mitochondrial DNA. GO:0030707 ovarian follicle cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030707 The process that occurs during oogenesis involving the ovarian follicle cells, somatic cells which surround the germ cells of an ovary. An example of this is found in Drosophila melanogaster. GO:0030708 germarium-derived female germ-line cyst encapsulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030708 Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the germarium. An example of this process is found in Drosophila melanogaster. CHEBI:42485 formyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_42485 GO:0030705 cytoskeleton-dependent intracellular transport biolink:BiologicalProcess go-plus goslim_generic|goslim_chembl|goslim_drosophila http://purl.obolibrary.org/obo/GO_0030705 The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell. GO:0030706 germarium-derived oocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030706 oocyte cell differentiation The process in which one relatively unspecialized immature cystocyte of the germ-line cyst in the germarium acquires the specialized features of an oocyte. An example of this process can be found in Drosophila melanogaster. CHEBI:134213 (S)-1,2,9,10-tetramethoxy-6-methylaporphine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134213 CHEBI:134214 L-xylo-3-hexulose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134214 CHEBI:134211 (R)-tetrahydropapaverine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134211 CHEBI:134212 (S)-glaucine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134212 CHEBI:134217 N-methylbulbocapnine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134217 CHEBI:134215 bulbocapnine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134215 CHEBI:134216 muricholic acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134216 CHEBI:134210 (R)-laudanosine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134210 PO:0000021 petal primordium biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0000021 petal primordia (exact, plural)|primordio de pétalo (Spanish, exact)|portion of petal primordium tissue (exact)|花弁原基（可視的） (Japanese, exact) A phyllome primordium (PO:0025128) that develops from a petal anlagen (PO:0025484) and is committed to the development of a petal (PO:0009032). CHEBI:437678 (S)-columbianetin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_437678 UBERON:0019293 white matter of pontine tegmentum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0019293 predominantly white regional part of pontine tegmentum|white matter of pontile tegmentum|white substance of pontile tegmentum|substantia alba tegmenti pontis|pontine white matter tracts UBERON:0019294 commissure of telencephalon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0019294 telencephalic commissures UBERON:0019291 white matter of metencephalon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0019291 UBERON:0019292 white matter of pons biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0019292 CHEBI:6457 lignin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_6457 GO:0015296 anion:cation symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015296 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion(out) + cation(out) = anion(in) + cation(in). GO:0015297 antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015297 Reactome:R-HSA-2731002|Reactome:R-HSA-2730959|Reactome:R-HSA-2730692 ion antiporter activity|exchanger|solute:solute exchange|porter|antiport|solute:solute antiporter activity|exchange transporter activity|countertransporter activity Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. The reaction is: solute A(out) + solute B(in) = solute A(in) + solute B(out). GO:0015298 solute:cation antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015298 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + cation(in) = solute(in) + cation(out). GO:0015299 solute:proton antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015299 Reactome:R-HSA-597628|Reactome:R-HSA-5625574|Reactome:R-HSA-434650 solute:hydrogen antiporter activity|L-arabinose/beta-D-thiogalactopyranoside:hydrogen antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + H+(in) = solute(in) + H+(out). GO:0015292 uniporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015292 uniport|facilitated diffusion carrier|single-species transporter activity Catalysis of the transport of a single molecular species across a membrane; transport is independent of the movement of any other molecular species. GO:0015293 symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015293 symport|cotransporter activity|porter activity Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. GO:0015294 solute:cation symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015294 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + cation(out) = solute(in) + cation(in). GO:0015295 solute:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015295 proline/glycine/betaine:hydrogen/sodium symporter activity|L-idonate/D-gluconate:hydrogen symporter activity|low affinity metal ion uptake transporter activity|heavy metal ion:hydrogen symporter activity|solute:hydrogen symporter activity|high affinity metal ion uptake transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + H+(out) = solute(in) + H+(in). GO:0015280 ligand-gated sodium channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015280 Reactome:R-HSA-2672334 acid-sensing ion channel activity|ASIC activity|epithelial sodium channel|amiloride-sensitive sodium channel activity Enables the transmembrane transfer of a sodium ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts. GO:0015278 calcium-release channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015278 intracellular ligand-gated calcium channel activity Enables the transmembrane transfer of a calcium ion from intracellular stores by a channel that opens when a specific intracellular ligand has been bound by the channel complex or one of its constituent parts. GO:0015279 store-operated calcium channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015279 Reactome:R-HSA-434798 A ligand-gated ion channel activity which transports calcium in response to emptying of intracellular calcium stores. GO:0015274 organellar voltage-gated chloride channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015274 organellar voltage gated chloride channel activity|organellar voltage-dependent chloride channel activity Enables the transmembrane transfer of a chloride ion by a voltage-gated channel. The membrane is an organellar membrane. GO:0015275 stretch-activated, cation-selective, calcium channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015275 Enables the transmembrane transfer of a calcium ion by a channel that opens in response to a mechanical stress in the form of stretching. GO:0015276 ligand-gated ion channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015276 Reactome:R-HSA-622326|Reactome:R-HSA-451311|Reactome:R-HSA-451310|Reactome:R-HSA-629595|Reactome:R-HSA-622325 ionotropic receptor activity Enables the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts. GO:0015277 kainate selective glutamate receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015277 An ionotropic glutamate receptor activity that exhibits fast gating by glutamate, acts by opening a cation channel permeable to sodium and potassium, and for which kainate is an agonist. GO:0015270 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015270 GO:0015271 outward rectifier potassium channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015271 Enables the transmembrane transfer of a potassium ion by an outwardly-rectifying voltage-gated channel. An outwardly rectifying current-voltage relation is one where at any given driving force the outward flow of K+ ions exceeds the inward flow for the opposite driving force. GO:0015272 ATP-activated inward rectifier potassium channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015272 Reactome:R-HSA-5683209 Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel, where the inward rectification is due to a voltage-dependent block of the channel pore by ATP. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force. GO:0015273 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015273 GO:0015290 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015290 GO:0015291 secondary active transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015291 Reactome:R-HSA-199216|TC:2.A secondary carrier-type facilitators|ion-gradient-driven energizer activity|galactose/glucose (methylgalactoside) porter activity|porters|electrochemical potential-driven transporter activity|multidrug endosomal transmembrane transporter activity|porter activity|coupled carrier|heavy metal ion porter activity|energizer of outer membrane receptor-mediated transport activity|nitrite/nitrate porter activity|active transporter Enables the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy, not direct ATP coupling. Secondary active transporters include symporters and antiporters. GO:0015289 obsolete pore-forming toxin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015289 pore-forming toxin activity OBSOLETE. Catalysis of the transport of electrolytes and other small molecules across a cell membrane. They are synthesized by one cell and secreted for insertion into the membrane of another cell where they form transmembrane pores. They may exert their toxic effects by allowing the free flow of electrolytes and other small molecules across the membrane, or they may allow entry into the target cell cytoplasm of a toxin protein that ultimately kills the cell. GO:0015285 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015285 GO:0015286 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015286 GO:0015287 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015287 GO:0015288 porin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015288 Wikipedia:Porin_(protein) porin|outer membrane exporter porin Enables the transfer of substances, sized less than 1000 Da, from one side of a membrane to the other. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria. CHEBI:6444 Levorphanol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_6444 GO:0015281 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015281 GO:0015282 obsolete NADPH oxidase-associated cytochrome b558 hydrogen channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015282 NADPH oxidase-associated cytochrome b558 hydrogen channel activity|NADPH oxidase-associated cytochrome b558 proton channel OBSOLETE. This term was not defined before being made obsolete. GO:0015283 obsolete apoptogenic cytochrome c release channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015283 apoptogenic cytochrome c release channel activity|Bcl-2 OBSOLETE. This term was not defined before being made obsolete. GO:0015284 fructose uniporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015284 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fructose(out) = fructose(in). UBERON:0034873 bodily gas biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034873 gas in anatomical space|portion of gas in anatomical space Any substance in the body or expelled from the body that is in a gaseous state. UBERON:0034874 air in respiratory system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034874 respiratory air|respiratory system air Any portion of gas located in a part of the respiratory system that is composed primarily of air. UBERON:0034875 future pituitary gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034875 pituitary primordium UBERON:0010899 synchronous hermaphroditic organism biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010899 serially hermaphroditic organism|simultaneous hermaphroditic organism Hermaphroditic organism that produces both male and female gametes at the same time. CHEBI:17428 (R)-reticuline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17428 CHEBI:17429 3-ketosucrose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17429 CHEBI:17426 5-dehydro-D-gluconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17426 CHEBI:17427 3-hydroxy-L-aspartate residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17427 CHEBI:17424 4-carboxy-2-hydroxy-cis,cis-muconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17424 CHEBI:17425 1-pyrroline-2-carboxylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17425 CHEBI:6495 lipoprotein biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_6495 CHEBI:17422 P(1),P(4)-bis(5'-adenosyl) tetraphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17422 CHEBI:17420 tetrahydropteroyltri-L-glutamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17420 CHEBI:17421 heparan sulfate N-acetyl-alpha-D-glucosaminide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17421 CHEBI:6499 lipoxin B4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_6499 CHEBI:6497 lipoxin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_6497 CHEBI:6498 lipoxin A4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_6498 GO:0005901 caveola biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005901 Wikipedia:Caveolae caveolar membrane|caveolae A membrane raft that forms small pit, depression, or invagination that communicates with the outside of a cell and extends inward, indenting the cytoplasm and the cell membrane. Examples include flask-shaped invaginations of the plasma membrane in adipocytes associated with caveolin proteins, and minute pits or incuppings of the cell membrane formed during pinocytosis. Caveolae may be pinched off to form free vesicles within the cytoplasm. GO:0005902 microvillus biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0005902 Wikipedia:Microvillus|NIF_Subcellular:sao671419673 microvilli Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells. GO:0005900 oncostatin-M receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005900 A heterodimeric receptor for the cytokine oncostatin-M (OSM). In humans the receptor complex is made up of the gene products gp130 and OSMR-beta. UBERON:0010890 pelvic complex muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010890 lower limb muscle|muscle of pelvic girdle and leg|pelvic girdle or posterior limb muscle|pelvic girdle or hind limb muscle|pelvic girdle and hind limb muscles|muscle of lower limb Muscles of the pelvic girdle, hindlimb or pelvic fin. UBERON:0010891 pectoral complex muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010891 muscle of pectoral girdle and wing|muscle of pectoral girdle and limb|muscle of upper limb|pectoral girdle and fore limb muscles|upper limb muscle A muscle of a pectoral girdle, pectoral fin or anterior limb. UBERON:0010894 keratinous tooth biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010894 horny denticle UBERON:0010893 median external naris biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010893 median nostril|nasohypophysial opening|median anterior naris Am unpaired external naris that lies in the midline of the head. UBERON:0034876 future neurohypophysis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034876 neurohypophyseal bud|neurohypohysial region the outgrowth of neuroectoderm located on the floor of the embryonic hypothalamus that gives rise to the neurohypophysis (posterior lobe) of the pituitary gland CHEBI:17419 3-hydroxy-cis,cis-muconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17419 UBERON:0034878 prechordal mesoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034878 prechordal mesenchyme the area of axial mesoderm that develops into the prechordal plate CHEBI:17417 N-caffeoylputrescine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17417 UBERON:0010885 hindlimb cartilage element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010885 hindlimb cartilage condensation A cartilaginous condensation that has the potential to develop into a hindlimb bone. UBERON:0010886 hindlimb pre-cartilage condensation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010886 hindlimb pre-cartilage condensation A pre-cartilage condensation that has the potential to develop into a hindlimb bone. CHEBI:17418 valeric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17418 CHEBI:17415 2,5-dioxopentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17415 CHEBI:17416 3,4-dihydroxyphthalic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17416 CHEBI:17413 2-(hydroxymethyl)-4-oxobutanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17413 GO:0005909 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005909 CHEBI:17412 R'C(R)S-S(R)CR' biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17412 GO:0005907 obsolete HA1 clathrin adaptor biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005907 AP1|HA1 clathrin adaptor OBSOLETE. (Was not defined before being made obsolete). GO:0005908 obsolete HA2 clathrin adaptor biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005908 AP2|HA2 clathrin adaptor OBSOLETE. (Was not defined before being made obsolete). CHEBI:17410 pteridine-2,4,6,7-tetrol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17410 GO:0005905 clathrin-coated pit biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005905 NIF_Subcellular:sao1969557946 coated pit A part of the endomembrane system in the form of an invagination of a membrane upon which a clathrin coat forms, and that can be converted by vesicle budding into a clathrin-coated vesicle. Coated pits form on the plasma membrane, where they are involved in receptor-mediated selective transport of many proteins and other macromolecules across the cell membrane, in the trans-Golgi network, and on some endosomes. GO:0005906 obsolete clathrin adaptor biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005906 adaptin|clathrin adaptor OBSOLETE. (Was not defined before being made obsolete). GO:0005903 brush border biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0005903 Wikipedia:Brush_border The dense covering of microvilli on the apical surface of an epithelial cell in tissues such as the intestine, kidney, and choroid plexus; the microvilli aid absorption by increasing the surface area of the cell. GO:0005904 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005904 UBERON:0010883 forelimb cartilage element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010883 forelimb wing cartilaginous condensation|wing cartilaginous condensation A cartilaginous condensation that has the potential to develop into a forelimb bone. UBERON:0010884 forelimb bone pre-cartilage condensation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010884 wing bone pre-cartilage condensation A pre-cartilage condensation that has the potential to develop into a forelimb bone. UBERON:0010881 limb cartilage element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010881 A skeletal element that is part of a limb and composed of cartilage tissue. UBERON:0010882 limb bone pre-cartilage condensation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010882 A skeletal element that is part of a limb and composed of pre-cartilage tissue. CHEBI:17448 methanofuran biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17448 CHEBI:17446 3-D-glucuronosyl-N(2),6-disulfo-beta-D-glucosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17446 CHEBI:17447 geraniol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17447 UBERON:0009891 facial mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009891 mesenchyme of face|face mesenchyme Mesenchyme that is part of a developing face. CHEBI:17445 3-hydroxyphenylacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17445 CHEBI:17442 4-(2-aminophenyl)-2,4-dioxobutanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17442 CHEBI:6472 lincomycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_6472 CHEBI:17443 L-homocitrulline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17443 CHEBI:17440 4-nitrophenyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17440 CHEBI:17441 chlorite biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17441 UBERON:0019206 tongue papilla epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0019206 UBERON:0019207 chorioretinal region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0019207 choroid and retina|retinachoroidal region|chorioretina|retinachoroid The part of the eye that consists of both the retina and the optic choroid UBERON:0019204 skin epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0019204 Any region of epithelium that is part of a skin region. UBERON:0009887 interlobar vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009887 interlobar vein of kidney|venae interlobares renis|venae interlobares renis|set of interlobar veins of kidney|interlobar veins of kidney The interlobar veins are veins of the renal circulation which drain the renal lobes. UBERON:0034898 alveolar ridge of premaxilla biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034898 pars dentalis of premaxilla The thickened ridge of bone that contains the tooth sockets on the premaxilla. UBERON:0009889 secondary heart field biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009889 SHF|anterior/second heart field|anterior heart field|second heart field A specific region of the lateral mesoderm that will form the majority of the mesodermal component of the right ventricle, arterial pole (outflow tract) and venous pole (inflow tract). CHEBI:17439 cyanocob(III)alamin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17439 CHEBI:17437 dimethyl sulfide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17437 CHEBI:17438 O-beta-D-xylosylzeatin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17438 CHEBI:17435 naphthalene-1,2-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17435 CHEBI:17436 (R)-5-phosphomevalonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17436 CHEBI:17433 queuine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17433 UBERON:0009880 carpal skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009880 fore mesopodial skeleton|ossa carpi|set of carpal bones|ossa carpi|fore mesopodium skeleton|carpal bones set|carpal bones|carpus|skeletal parts of fore mesopodium|skeleton of carpus|fore mesopodium Subdivision of skeleton that consists of the endochondral elements distal to the anterior limb/fin zeugopodial skeletal elements which constitute the proximal region of the anterior autopod skeleton[PHENOSCAPE:ad]. CHEBI:17434 trimethylsulfonium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17434 CHEBI:17431 agmatine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17431 UBERON:0009881 anterior lateral plate mesoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009881 ALPM UBERON:0009883 medullary ray biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009883 Ferrein's pyramid|kidney medullary ray|renal medullary ray A renal, cortical lobule, consisting of the ascending or descending limbs of the loop of Henle or of the collecting tubules; medullary rays are regions where parallel arrays of straight tubules travel perpendicular to the capsule and extend from the cortex to the medulla. UBERON:0009885 interlobar artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009885 arteriae interlobares renis|set of interlobar arteries of kidney|arteriae interlobares renis|renal interlobar artery|interlobar artery of kidney|interlobar arteries of kidney|kidney interlobar artery An artery that supplies a renal lobe. UBERON:0019269 gray matter of diencephalon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0019269 UBERON:0019267 gray matter of midbrain biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0019267 UBERON:0019264 gray matter of forebrain biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0019264 UBERON:0019262 white matter of myelencephalon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0019262 myelencephalic white matter A white matter that is part of the myelencephalon. UBERON:0019263 gray matter of hindbrain biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0019263 gray matter of the hindbrain UBERON:0019261 white matter of forebrain biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0019261 A white matter that is part of the forebrain. UBERON:0019258 white matter of hindbrain biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0019258 A white matter that is part of the hindbrain. CHEBI:17408 monoacylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17408 CHEBI:17409 10-hydroxycapric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17409 CHEBI:17406 3-(imidazol-5-yl)pyruvic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17406 CHEBI:17407 2-trans,6-trans-farnesyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17407 CHEBI:17404 indan-1-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17404 CHEBI:17405 4-pyridoxic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17405 CHEBI:17402 2-methylpropanoyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17402 CHEBI:17403 3-chloro-L-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17403 CHEBI:17400 raucaffricine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17400 CHEBI:17401 myo-inositol hexakisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17401 GO:0030813 positive regulation of nucleotide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030813 upregulation of nucleotide catabolic process|stimulation of nucleotide catabolic process|up-regulation of nucleotide catabolic process|activation of nucleotide catabolic process|positive regulation of nucleotide degradation|positive regulation of nucleotide breakdown|positive regulation of nucleotide catabolism|up regulation of nucleotide catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides. GO:0005857 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005857 GO:0005858 axonemal dynein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005858 axonemal dynein heavy chain|axonemal dynein intermediate light chain|axonemal dynein light chain|axonemal dynein intermediate chain A dynein complex found in eukaryotic cilia and flagella; the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion. GO:0030814 obsolete regulation of cAMP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030814 regulation of 3',5' cAMP metabolism|regulation of 3',5'-cAMP metabolic process|regulation of cyclic AMP metabolism|regulation of adenosine 3',5'-cyclophosphate metabolic process|regulation of cAMP metabolism|regulation of adenosine 3',5'-cyclophosphate metabolism|regulation of cyclic AMP metabolic process|regulation of 3',5'-cAMP metabolism|regulation of 3',5' cAMP metabolic process OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate). CHEBI:17393 D-allose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17393 GO:0030811 regulation of nucleotide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030811 regulation of nucleotide catabolism|regulation of nucleotide degradation|regulation of nucleotide breakdown Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides. CHEBI:17390 allocryptopine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17390 GO:0005855 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005855 GO:0030812 negative regulation of nucleotide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030812 down regulation of nucleotide catabolic process|inhibition of nucleotide catabolic process|negative regulation of nucleotide degradation|negative regulation of nucleotide breakdown|down-regulation of nucleotide catabolic process|downregulation of nucleotide catabolic process|negative regulation of nucleotide catabolism Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides. GO:0005856 cytoskeleton biolink:CellularComponent go-plus goslim_chembl|goslim_mouse|goslim_agr|goslim_yeast|goslim_candida|goslim_pir|goslim_plant|goslim_drosophila|goslim_aspergillus|goslim_generic|goslim_flybase_ribbon http://purl.obolibrary.org/obo/GO_0005856 Wikipedia:Cytoskeleton Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles. CHEBI:17391 5-O-(indol-3-ylacetyl)-myo-inositol D-galactoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17391 GO:0005853 eukaryotic translation elongation factor 1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005853 A multisubunit nucleotide exchange complex that binds GTP and aminoacyl-tRNAs, and catalyzes their codon-dependent placement at the A-site of the ribosome. In humans, the complex is composed of four subunits, alpha, beta, delta and gamma. GO:0005854 nascent polypeptide-associated complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005854 NACA|NAC A heterodimeric protein complex that can reversibly bind to ribosomes, and is located in direct proximity to newly synthesized polypeptide chains as they emerge from the ribosome. GO:0030810 positive regulation of nucleotide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030810 positive regulation of nucleotide synthesis|positive regulation of nucleotide formation|up-regulation of nucleotide biosynthetic process|upregulation of nucleotide biosynthetic process|up regulation of nucleotide biosynthetic process|positive regulation of nucleotide biosynthesis|positive regulation of nucleotide anabolism|activation of nucleotide biosynthetic process|stimulation of nucleotide biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides. GO:0005851 eukaryotic translation initiation factor 2B complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005851 eif2B|eIF-2B A multisubunit guanine nucleotide exchange factor which catalyzes the exchange of GDP bound to initiation factor eIF2 for GTP, generating active eIF2-GTP. In humans, it is composed of five subunits, alpha, beta, delta, gamma and epsilon. GO:0005852 eukaryotic translation initiation factor 3 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005852 eIF3|eIF-3 A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs. GO:0005850 eukaryotic translation initiation factor 2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005850 Wikipedia:EIF-2 eIF2|eIF-2 Complex of three heterogeneous polypeptide chains, that form a ternary complex with initiator methionyl-tRNA and GTP. This ternary complex binds to free 40S subunit, which subsequently binds the 5' end of mRNA. GO:0030819 obsolete positive regulation of cAMP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030819 upregulation of cAMP biosynthetic process|positive regulation of 3',5' cAMP biosynthetic process|positive regulation of 3',5' cAMP biosynthesis|positive regulation of cyclic AMP biosynthetic process|positive regulation of cyclic AMP biosynthesis|up regulation of cAMP biosynthetic process|positive regulation of cAMP anabolism|activation of cAMP biosynthetic process|positive regulation of adenosine 3',5'-cyclophosphate biosynthesis|positive regulation of adenosine 3',5'-cyclophosphate biosynthetic process|positive regulation of cAMP biosynthesis|positive regulation of cAMP synthesis|positive regulation of 3',5'-cAMP biosynthesis|stimulation of cAMP biosynthetic process|positive regulation of 3',5'-cAMP biosynthetic process|positive regulation of cAMP formation|up-regulation of cAMP biosynthetic process OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate). CHEBI:42355 erythromycin A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_42355 GO:0030817 obsolete regulation of cAMP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030817 regulation of cyclic AMP biosynthesis|regulation of cyclic AMP biosynthetic process|regulation of adenosine 3',5'-cyclophosphate biosynthesis|regulation of adenosine 3',5'-cyclophosphate biosynthetic process|regulation of cAMP biosynthesis|regulation of 3',5'-cAMP biosynthetic process|regulation of 3',5'-cAMP biosynthesis|regulation of cAMP anabolism|regulation of cAMP synthesis|regulation of cAMP formation|regulation of 3',5' cAMP biosynthesis|regulation of 3',5' cAMP biosynthetic process OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate). GO:0030818 obsolete negative regulation of cAMP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030818 down regulation of cAMP biosynthetic process|negative regulation of 3',5' cAMP biosynthetic process|negative regulation of cAMP anabolism|negative regulation of 3',5' cAMP biosynthesis|downregulation of cAMP biosynthetic process|negative regulation of cAMP synthesis|negative regulation of cyclic AMP biosynthesis|negative regulation of cyclic AMP biosynthetic process|negative regulation of cAMP formation|down-regulation of cAMP biosynthetic process|negative regulation of cAMP biosynthesis|negative regulation of adenosine 3',5'-cyclophosphate biosynthetic process|negative regulation of adenosine 3',5'-cyclophosphate biosynthesis|negative regulation of 3',5'-cAMP biosynthetic process|negative regulation of 3',5'-cAMP biosynthesis|inhibition of cAMP biosynthetic process OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate). GO:0030815 obsolete negative regulation of cAMP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030815 negative regulation of cyclic AMP metabolic process|downregulation of cAMP metabolic process|negative regulation of 3',5' cAMP metabolic process|down regulation of cAMP metabolic process|negative regulation of 3',5' cAMP metabolism|inhibition of cAMP metabolic process|negative regulation of cyclic AMP metabolism|negative regulation of cAMP metabolism|negative regulation of adenosine 3',5'-cyclophosphate metabolism|negative regulation of 3',5'-cAMP metabolism|negative regulation of 3',5'-cAMP metabolic process|down-regulation of cAMP metabolic process|negative regulation of adenosine 3',5'-cyclophosphate metabolic process OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate). GO:0030816 obsolete positive regulation of cAMP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030816 positive regulation of 3',5'-cAMP metabolic process|positive regulation of adenosine 3',5'-cyclophosphate metabolic process|up regulation of cAMP metabolic process|positive regulation of cyclic AMP metabolic process|positive regulation of 3',5' cAMP metabolism|positive regulation of 3',5' cAMP metabolic process|upregulation of cAMP metabolic process|positive regulation of cyclic AMP metabolism|positive regulation of cAMP metabolism|positive regulation of adenosine 3',5'-cyclophosphate metabolism|stimulation of cAMP metabolic process|positive regulation of 3',5'-cAMP metabolism|up-regulation of cAMP metabolic process|activation of cAMP metabolic process OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate). UBERON:0009953 post-embryonic organism biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009953 post-natal organism|postnatal mouse|TS28 mouse|post-hatching organism|postnatal organism A multicellular organism that existence_starts_with a post-embryonic stage. UBERON:0009955 neurogenic placode biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009955 placodae neurogenicae|neurogenic placodes Cranial ectodermal placode with potential to develop into a component of the nervous system, such as nerves or ganglia. UBERON:0034901 cervical sympathetic nerve trunk biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034901 cervical sympathetic trunk|cervical sympathetic chain|cervical part of sympathetic trunk The cervical ganglia are paravertebral ganglia of the sympathetic nervous system. These emerging postganglionic nerves synapse with preganglionic nerves from the thoracic spinal cord. They consist of three paravertebral ganglia: superior cervical ganglion middle cervical ganglion inferior cervical ganglion. The inferior ganglion may be fused with the first thoracic ganglion to form a single structure, the stellate ganglion. Nerves emerging from cervical sympathetic ganglia contribute to the cardiac plexus, among other things. UBERON:0034903 left atrium endocardium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034903 endocardium of left atrium|left atrium endocardial tissue|left atrial endocardium Endocardium that is part of the left atrium. UBERON:0009958 bladder lumen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009958 urinary bladder lumen|lumen of urinary bladder|bladder cavity|cavity of urinary bladder A anatomical space that is enclosed by a urinary bladder. UBERON:0034905 gland lumen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034905 lumen of gland CHEBI:17389 2-monoglyceride biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17389 UBERON:0034907 pineal parenchyma biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034907 Parenchymal tissue that forms the pineal gland. UBERON:0034908 scapular muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034908 Any of the muscles that are responsible for moving the scapula. In humans these are the levator scapulae, the infraspinatus muscle, the teres major, the teres minor, and the supraspinatus muscle. CHEBI:17387 O-acylcarnitine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17387 CHEBI:17388 (S)-1-pyrroline-5-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17388 UBERON:0034909 intermaxillary suture biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034909 intermaxillary suture of skull A cranial suture in the midline of the skull that connects the left and right maxilla bones CHEBI:17385 3-(4-hydroxyphenyl)lactic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17385 GO:0005859 muscle myosin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005859 A filament of myosin found in a muscle cell of any type. CHEBI:17383 GDP-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17383 CHEBI:17384 17-O-acetylnorajmaline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17384 GO:0030802 obsolete regulation of cyclic nucleotide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030802 regulation of cyclic nucleotide biosynthesis|regulation of cyclic nucleotide anabolism|regulation of cyclic nucleotide synthesis|regulation of cyclic nucleotide formation OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cyclic nucleotides. GO:0005868 cytoplasmic dynein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005868 cytoplasmic dynein intermediate chain|cytoplasmic dynein heavy chain|cytoplasmic dynein intermediate light chain|cytoplasmic dynein light chain Any dynein complex with a homodimeric dynein heavy chain core that catalyzes movement along a microtubule. Cytoplasmic dynein complexes participate in many cytoplasmic transport activities in eukaryotes, such as mRNA localization, intermediate filament transport, nuclear envelope breakdown, apoptosis, transport of centrosomal proteins, mitotic spindle assembly, virus transport, kinetochore functions, and movement of signaling and spindle checkpoint proteins. Some complexes participate in intraflagellar transport. Subunits associated with the dynein heavy chain mediate association between dynein heavy chain and cargoes, and may include light chains and light intermediate chains. CHEBI:17381 porphobilinogen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17381 GO:0030803 obsolete negative regulation of cyclic nucleotide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030803 negative regulation of cyclic nucleotide anabolism|negative regulation of cyclic nucleotide synthesis|negative regulation of cyclic nucleotide formation|downregulation of cyclic nucleotide biosynthetic process|down regulation of cyclic nucleotide biosynthetic process|inhibition of cyclic nucleotide biosynthetic process|down-regulation of cyclic nucleotide biosynthetic process|negative regulation of cyclic nucleotide biosynthesis OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cyclic nucleotides. GO:0005869 dynactin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005869 A 20S multiprotein assembly of total mass about 1.2 MDa that activates dynein-based activity in vivo. A large structural component of the complex is an actin-like 40 nm filament composed of actin-related protein, to which other components attach. CHEBI:17382 5'-O-beta-D-glucosylpyridoxine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17382 GO:0030800 obsolete negative regulation of cyclic nucleotide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030800 negative regulation of cyclic nucleotide metabolism|down regulation of cyclic nucleotide metabolic process|downregulation of cyclic nucleotide metabolic process|down-regulation of cyclic nucleotide metabolic process|inhibition of cyclic nucleotide metabolic process OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving cyclic nucleotides. GO:0030801 obsolete positive regulation of cyclic nucleotide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030801 positive regulation of cyclic nucleotide metabolism|upregulation of cyclic nucleotide metabolic process|up regulation of cyclic nucleotide metabolic process|activation of cyclic nucleotide metabolic process|stimulation of cyclic nucleotide metabolic process|up-regulation of cyclic nucleotide metabolic process OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving cyclic nucleotides. CHEBI:17380 3-hydroxy-L-kynurenine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17380 GO:0005865 striated muscle thin filament biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005865 Filaments formed of actin and associated proteins; attached to Z discs at either end of sarcomeres in myofibrils. GO:0005862 muscle thin filament tropomyosin biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005862 A form of the tropomyosin dimer found associated with actin and the troponin complex in muscle thin filaments. GO:0005863 striated muscle myosin thick filament biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005863 Bipolar filaments formed of polymers of a muscle-specific myosin II isoform, found in the middle of sarcomeres in myofibrils. GO:0005860 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005860 GO:0005861 troponin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005861 A complex of accessory proteins (typically troponin T, troponin I and troponin C) found associated with actin in muscle thin filaments; involved in calcium regulation of muscle contraction. GO:0030808 regulation of nucleotide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030808 regulation of nucleotide formation|regulation of nucleotide biosynthesis|regulation of nucleotide anabolism|regulation of nucleotide synthesis Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides. GO:0030809 negative regulation of nucleotide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030809 down regulation of nucleotide biosynthetic process|downregulation of nucleotide biosynthetic process|negative regulation of nucleotide anabolism|negative regulation of nucleotide synthesis|negative regulation of nucleotide formation|down-regulation of nucleotide biosynthetic process|negative regulation of nucleotide biosynthesis|inhibition of nucleotide biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides. GO:0030806 obsolete negative regulation of cyclic nucleotide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030806 inhibition of cyclic nucleotide catabolic process|down regulation of cyclic nucleotide catabolic process|downregulation of cyclic nucleotide catabolic process|negative regulation of cyclic nucleotide degradation|negative regulation of cyclic nucleotide breakdown|down-regulation of cyclic nucleotide catabolic process|negative regulation of cyclic nucleotide catabolism OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways resulting in the breakdown of cyclic nucleotides. GO:0030807 obsolete positive regulation of cyclic nucleotide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030807 positive regulation of cyclic nucleotide catabolism|up-regulation of cyclic nucleotide catabolic process|upregulation of cyclic nucleotide catabolic process|positive regulation of cyclic nucleotide degradation|positive regulation of cyclic nucleotide breakdown|up regulation of cyclic nucleotide catabolic process|activation of cyclic nucleotide catabolic process|stimulation of cyclic nucleotide catabolic process OBSOLETE. Any process that activates or increases the frequency, rate or extent of chemical reactions and pathways resulting in the breakdown of cyclic nucleotides. CHEBI:66331 xanthohumol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_66331 GO:0030804 obsolete positive regulation of cyclic nucleotide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030804 positive regulation of cyclic nucleotide synthesis|positive regulation of cyclic nucleotide biosynthesis|positive regulation of cyclic nucleotide formation|up regulation of cyclic nucleotide biosynthetic process|upregulation of cyclic nucleotide biosynthetic process|stimulation of cyclic nucleotide biosynthetic process|up-regulation of cyclic nucleotide biosynthetic process|activation of cyclic nucleotide biosynthetic process|positive regulation of cyclic nucleotide anabolism OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cyclic nucleotides. GO:0030805 regulation of cyclic nucleotide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030805 regulation of cyclic nucleotide catabolism|regulation of cyclic nucleotide degradation|regulation of cyclic nucleotide breakdown Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cyclic nucleotides. CHEBI:17378 D-glyceraldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17378 CHEBI:17379 isovitexin 2''-O-beta-D-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17379 CHEBI:17376 cystine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17376 CHEBI:17377 bergaptol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17377 CHEBI:17374 N(6)-acetyl-N(6)-hydroxy-L-lysine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17374 CHEBI:17375 (2S)-2-hydroxy monocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17375 CHEBI:17372 1,2-dihydrovomilenine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17372 GO:0005835 fatty acid synthase complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0005835 Wikipedia:Fatty_acid_synthetase_complex holo-[acyl-carrier-protein] synthase complex|cytosolic type I fatty acid synthase complex|cytosolic type I FAS complex|FAS complex|cytosolic FAS complex|cytosolic fatty acid synthase complex|fatty acid synthetase complex A multienzyme complex that catalyses the synthesis of fatty acids from acetyl CoA. GO:0005836 fatty-acyl-CoA synthase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005836 fatty acyl CoA synthase complex A protein complex that possesses fatty-acyl-CoA synthase activity. GO:0005833 hemoglobin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005833 haemoglobin complex An iron-containing, oxygen carrying complex. In vertebrates it is made up of two pairs of associated globin polypeptide chains, each chain carrying a noncovalently bound heme prosthetic group. GO:0005834 heterotrimeric G-protein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005834 heterotrimeric G-protein GTPase, gamma-subunit|heterotrimeric G-protein GTPase activity|heterotrimeric G-protein GTPase, alpha-subunit|heterotrimeric G-protein GTPase, beta-subunit Any of a family of heterotrimeric GTP-binding and hydrolyzing proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and RAS. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the beta and gamma subunits are tightly associated and function as a beta-gamma heterodimer; extrinsic plasma membrane proteins (cytoplasmic face) that function as a complex to transduce signals from G protein-coupled receptors to an effector protein. GO:0005831 steroid hormone aporeceptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005831 A protein complex consisting of a steroid receptor associated with nonreceptor proteins, minimally a dimer of Hsp90 and a monomer of hsp56/FKBP59; forms in the absence of bound ligand. GO:0005832 chaperonin-containing T-complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005832 CCT particle|TriC A multisubunit ring-shaped complex that mediates protein folding in the cytosol without a cofactor. GO:0005830 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005830 CHEBI:91309 lysophosphatidylcholine(18:2/0:0) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91309 UBERON:0034921 multi organ part structure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034921 anatomical cluster An multicellular anatomical structure that has subparts of multiple organs as a part. UBERON:0034922 cell cluster biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034922 A cluster of cells, largely surrounded by a morphological boundary. UBERON:0034923 disconnected anatomical group biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034923 Material anatomical entity consisting of multiple anatomical structures that are not connected to each other. UBERON:0010913 vertebral element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010913 vertebral endochondral element|vertebra element|vertebra endochondral element|vertebra skeletal element Skeletal element that forms around the notochord and is part of the vertebral column. CHEBI:91306 (20S,23)-dihydroxyvitamin D3 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91306 UBERON:0034925 anatomical collection biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034925 A collection of anatomical structures that are alike in terms of their morphology or developmental origin. UBERON:0010911 ossicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010911 Skeletal element that is often isolated, small, and variable in composition. CHEBI:91307 (20S,23,24)-trihydroxyvitamin D3 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91307 UBERON:0034926 anatomical row biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034926 An anatomical collection that is arranged in a line. UBERON:0010912 subdivision of skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton (in vivo)|skeletal subdivision Anatomical cluster consisting of the skeletal elements (i.e. bone elements, cartilage elements, cartilage condensations) that are part of an individual subdivision of the organism. Excludes joints. CHEBI:91308 (20S,23,25)-trihydroxyvitamin D3 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91308 UBERON:0034928 dorsal surface of penis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034928 dorsum penis|dorsum of penis CHEBI:91301 5,20-diHEPE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91301 CHEBI:91302 lysophosphatidylcholine(0:0/18:2) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91302 UBERON:0034929 external soft tissue zone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034929 A region or zone on the surface of an organism that encompasses skin and any adnexa, down through muscles and bounded by underlying skeletal support structures. CHEBI:91303 lysophosphatidylcholine(0:0/20:4) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91303 GO:0005839 proteasome core complex biolink:CellularComponent go-plus goslim_metagenomics http://purl.obolibrary.org/obo/GO_0005839 20S proteasome|PA28gamma-20S proteasome|macropain|20S core complex A multisubunit barrel shaped endoprotease complex, which is the core of the proteasome complex. GO:0005837 obsolete 26S proteasome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005837 26S proteasome OBSOLETE. A large multisubunit protease found in the cytosol that recognizes, unfolds, and digests protein substrates that have been marked for degradation by the attachment of a ubiquitin group. Individual subcomplexes of the complete 26S proteasome are involved in these different tasks: the ATP-dependent 19S caps are believed to unfold substrates and feed them to the actual protease, the 20S proteasome. GO:0005838 proteasome regulatory particle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005838 PA700 proteasome activator|modulator complex|PA700-dependent proteasome activator|19S regulatory particle A multisubunit complex, which caps one or both ends of the proteasome core complex. This complex recognizes and unfolds ubiquitinated proteins, and translocates them to the proteasome core complex. CHEBI:91300 (9Z,12R)-12,18-dihydroxyoctadecenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91300 GO:0005846 nuclear cap binding complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005846 mRNA cap binding complex|CBC|NCBP-NIP1 complex|snRNA cap binding complex A conserved heterodimeric protein complex that binds to the 5' terminal cap structure m7G(5')ppp(5')N of nascent eukaryotic RNA polymerase II transcripts such as pre-mRNA and U snRNA. The consists of proteins known as CBP20 and CBP80, binds to cap structures in the nucleus, and is involved in pre-mRNA splicing, 3'-end formation, and RNA nuclear export. GO:0005847 mRNA cleavage and polyadenylation specificity factor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005847 CPSF complex|cleavage and polyadenylylation specificity factor activity|CPF complex|CFII complex A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal. GO:0005844 polysome biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0005844 Wikipedia:Polysome|NIF_Subcellular:sao1038025871 polyribosome A multiribosomal structure representing a linear array of ribosomes held together by messenger RNA. They represent the active complexes in cellular protein synthesis and are able to incorporate amino acids into polypeptides both in vivo and in vitro. GO:0005845 mRNA cap binding complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005845 mRNA cap complex Any protein complex that binds to an mRNA cap at any time in the lifetime of the mRNA. GO:0005842 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005842 GO:0005843 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005843 GO:0005840 ribosome biolink:CellularComponent go-plus goslim_metagenomics|goslim_aspergillus|goslim_generic|goslim_chembl|goslim_yeast|goslim_candida|goslim_plant|goslim_pir http://purl.obolibrary.org/obo/GO_0005840 Wikipedia:Ribosome|NIF_Subcellular:sao1429207766 free ribosome|ribosomal RNA|membrane bound ribosome An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins. UBERON:0009917 kidney corticomedullary boundary biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009917 The region demarcating the renal medulla from the surrounding cortex; end-stage renal failure may be associated with loss of the normal corticomedullary boundary UBERON:0009918 retrotrapezoid nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009918 The loose collection of neurons that reside in the rostral medulla close to the medullary surface, ventral and immediately caudal of nVII, that are crucial for CO2 sensing in the brain UBERON:0009919 ureter smooth muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009919 ureteral smooth muscle layer|ureteral smooth muscle The smooth muscle tissue surrounding the epithelium of the ureter UBERON:0009920 optic neural crest biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009920 UBERON:0034932 epithelium of biliary system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034932 biliary epithelium|biliary system epithelium|biliary tract epithelium The epithelial layer covering the biliary system. This includes the epithelium of the gallbladder (when present) as well as the intrahepatic and extrahepatic bile ducts. UBERON:0034933 layer of smooth muscle tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034933 Any organ component layer that consists of smooth muscle tissue. UBERON:0010905 clavicle bone primordium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010905 clavicle primordium A primordium that develops into a clavicle bone. CHEBI:17399 L-xylulose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17399 CHEBI:17396 (R)-prunasin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17396 CHEBI:17397 3-methyloxindole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17397 GO:0005848 mRNA cleavage stimulating factor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005848 cleavage stimulation factor activity|CstF complex A protein complex required for mRNA cleavage but not for poly(A) addition. CHEBI:17394 N(5)-ethyl-L-glutamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17394 GO:0005849 mRNA cleavage factor complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0005849 Any macromolecular complex involved in cleavage or polyadenylation of mRNA molecules. CHEBI:17395 cis-caffeic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17395 GO:0005813 centrosome biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0005813 Wikipedia:Centrosome A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle. GO:0005814 centriole biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005814 Wikipedia:Centriole|NIF_Subcellular:sao95019936 daughter centriole|mother centriole A cellular organelle, found close to the nucleus in many eukaryotic cells, consisting of a small cylinder with microtubular walls, 300-500 nm long and 150-250 nm in diameter. It contains nine short, parallel, peripheral microtubular fibrils, each fibril consisting of one complete microtubule fused to two incomplete microtubules. Cells usually have two centrioles, lying at right angles to each other. At division, each pair of centrioles generates another pair and the twin pairs form the pole of the mitotic spindle. GO:0005811 lipid droplet biolink:CellularComponent go-plus goslim_chembl|goslim_generic http://purl.obolibrary.org/obo/GO_0005811 adiposome|lipid particle|lipid body An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins. UBERON:0019310 glossopharyngeal nerve root biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0019310 glossopharyngeal nerve root UBERON:0019311 root of olfactory nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0019311 olfactory nerve root The initial segment of an olfactory nerve, leaving the central nervous system. GO:0005810 obsolete endocytotic transport vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005810 endocytotic transport vesicle OBSOLETE. (Was not defined before being made obsolete). CHEBI:32988 amide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32988 UBERON:0019319 exocrine gland of integumental system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0019319 integumental system exocrine gland|integumental exocrine gland An exocrine gland that is part of a integumental system. CHEBI:32989 N(omega)-phosphohypotaurocyamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32989 UBERON:0010982 latissimus dorsi pre-muscle mass biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010982 UBERON:0010983 levator scapulae pre-muscle mass biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010983 PR:000004580 beta-2-microglobulin biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000004580 B2M A protein that is a translation product of the human B2M gene or a 1:1 ortholog thereof. UBERON:0019315 meibum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0019315 tarsal gland secretion an oily substance that prevents evaporation of the eye's tear film CHEBI:32980 phloretic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32980 CHEBI:17349 5-methyl-5,6,7,8-tetrahydromethanopterin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17349 CHEBI:17347 testosterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17347 CHEBI:17348 D-aldohexose 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17348 CHEBI:17345 guanosine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17345 CHEBI:17346 4-chlorophenylacetonitrile biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17346 GO:0005819 spindle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005819 Wikipedia:Spindle_apparatus The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart. CHEBI:17343 cis-3,4-leucopelargonidin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17343 CHEBI:17344 2-carboxy-cis,cis-muconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17344 GO:0005817 obsolete centrosomal mitotic factor biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005817 centrosomal mitotic factor OBSOLETE. (Was not defined before being made obsolete). GO:0005818 aster biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005818 An array of microtubules emanating from a spindle pole MTOC that do not connect to kinetochores. CHEBI:17342 L-2-aminohexano-6-lactam biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17342 GO:0005815 microtubule organizing center biolink:CellularComponent go-plus goslim_chembl|goslim_yeast|goslim_candida|goslim_generic http://purl.obolibrary.org/obo/GO_0005815 Wikipedia:Microtubule_organizing_center MTOC|microtubule organising centre An intracellular structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides. CHEBI:17340 cetraxate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17340 GO:0005816 spindle pole body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005816 Wikipedia:Spindle_pole_body SPB The microtubule organizing center in fungi; functionally homologous to the animal cell centrosome. GO:0005824 outer plaque of spindle pole body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005824 One of three laminate structures that form the spindle pole body; the outer plaque is in the cytoplasm. GO:0005825 half bridge of spindle pole body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005825 Structure adjacent to the plaques of the spindle pole body. GO:0005822 inner plaque of spindle pole body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005822 One of three laminate structures that form the spindle pole body; the inner plaque is in the nucleus. GO:0005823 central plaque of spindle pole body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005823 One of three laminate structures that form the spindle pole body; the central plaque is embedded in the nuclear envelope. GO:0005821 intermediate layer of spindle pole body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005821 Structure between the central and outer plaques of the spindle pole body. UBERON:0019307 epithelium of external nose biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0019307 epithelium of skin of external nose Epithelial layer that is part of the external part of the nose. UBERON:0019306 nose epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0019306 UBERON:0019304 sensory organ epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0019304 UBERON:0010963 trunk and cervical myotome group biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010963 CHEBI:17338 CDP-3,6-dideoxy-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17338 CHEBI:17339 N(5)-acyl-L-ornithine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17339 CHEBI:17336 all-trans-retinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17336 CHEBI:17337 (2-chloro-5-oxo-2,5-dihydro-2-furyl)acetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17337 CHEBI:17334 penicillin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17334 CHEBI:17335 4-O-beta-D-glucosyl-4-coumaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17335 CHEBI:17332 planteose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17332 CHEBI:17333 chorismic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17333 GO:0005828 kinetochore microtubule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005828 pole-to-kinetochore microtubule Any of the spindle microtubules that attach to the kinetochores of chromosomes by their plus ends, and maneuver the chromosomes during mitotic or meiotic chromosome segregation. GO:0005829 cytosol biolink:CellularComponent go-plus goslim_plant|goslim_drosophila|goslim_aspergillus|goslim_generic|goslim_flybase_ribbon|goslim_chembl|goslim_mouse|goslim_agr http://purl.obolibrary.org/obo/GO_0005829 Wikipedia:Cytosol|NIF_Subcellular:sao101633890 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. CHEBI:17331 N-benzoylanthranilate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17331 GO:0005826 actomyosin contractile ring biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005826 cytokinetic ring|actomyosin ring|CAR|constriction ring|contractile actomyosin ring A cytoskeletal structure composed of actin filaments and myosin that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the spindle, i.e. the cell division plane. In animal cells, the contractile ring is located at the cleavage furrow. In budding fungal cells, e.g. mitotic S. cerevisiae cells, the contractile ring forms at the mother-bud neck before mitosis. CHEBI:91310 lysophosphatidylcholine(20:4/0:0) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91310 GO:0005827 polar microtubule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005827 pole-to-pole microtubule Any of the spindle microtubules that come from each pole and overlap at the spindle midzone. This interdigitating structure consisting of antiparallel microtubules is responsible for pushing the poles of the spindle apart. CHEBI:17371 macrocin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17371 CHEBI:32964 ornithinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32964 CHEBI:32965 N(3')-acetylgentamycin C biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32965 CHEBI:32966 beta-D-fructofuranose 1,6-bisphosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32966 CHEBI:32969 D-lombricine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32969 UBERON:0010955 trapezius pre-muscle mass biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010955 CHEBI:17369 D-mannose 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17369 CHEBI:32963 amidinoproclavaminic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32963 CHEBI:17367 2-hydroxy-6-oxonona-2,4-dienedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17367 CHEBI:17368 hypoxanthine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17368 UBERON:0010959 craniocervical muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010959 muscle of head or neck|muscle of head and neck Any muscle organ that is part of either the head or the neck. CHEBI:17365 2,4-dichloro-cis,cis-muconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17365 UBERON:0009970 epithelium of pancreatic duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009970 pancreatic duct epithelium|pancreatic ductal epithelium An epithelium that is part of a pancreatic duct. CHEBI:17363 D-ribulose 5-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17363 UBERON:0009972 ureteropelvic junction biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009972 pelvoureteric junction|pelviureteric junction The junction between the ureter and the renal pelvis of the kidney CHEBI:17364 D-aspartic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17364 UBERON:0009973 ureterovesical junction biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009973 vesico-ureteral junction|vesicoureteric junction|vesico-ureteric junction The valve-like structure found at the site of entry of the ureter into the urinary bladder, normally displays an oblique angulation through the detrusor to avoid reflux of urine up the ureters and the kidney CHEBI:17361 cytidine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17361 CHEBI:17362 quinoline biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17362 UBERON:0009974 lumen of Rathke's pouch biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009974 Rathkes pouch invagination An anatomical cavity that surrounded_by a Rathke's pouch. GO:0005802 trans-Golgi network biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005802 NIF_Subcellular:sao9456487 Golgi trans face|late Golgi|trans Golgi network|TGN|trans face|Golgi trans-face|maturing face The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination. CHEBI:17360 D-altronate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17360 GO:0005803 obsolete secretory vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005803 secretory vesicle|transition vesicle OBSOLETE. A small subcellular vesicle, or granule, surrounded by a single-layered membrane; formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. GO:0005800 obsolete COPII vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005800 COPII vesicle OBSOLETE. (Was not defined before being made obsolete). GO:0005801 cis-Golgi network biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005801 NIF_Subcellular:sao632188024 Golgi cis face|cis Golgi network|cis face|forming face|Golgi cis-face The network of interconnected tubular and cisternal structures located at the convex side of the Golgi apparatus, which abuts the endoplasmic reticulum. CHEBI:32975 (R)-2,3,4,5-tetrahydrodipicolinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32975 CHEBI:32976 2,3,4,5-tetrahydrodipicolinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32976 CHEBI:32978 (R)-3-phenyllactic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32978 CHEBI:32979 (S)-3-phenyllactate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32979 CHEBI:32970 2-aminoethanesulfonate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32970 CHEBI:32971 3,4,6-trichlorocatechol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32971 CHEBI:17358 N(4)-phosphoagmatine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17358 CHEBI:17359 sulfite biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17359 CHEBI:17356 2-acetamidofluorene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17356 CHEBI:17357 L-rhamnonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17357 UBERON:0010948 cleidooccipital muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010948 cleidooccipital|cleido-occipitalis muscle|cleido-occipitalis A muscle organ that attaches_to a clavicle and attaches_to a occipital bone. GO:0005808 obsolete Golgi-plasma membrane transport vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005808 Golgi-plasma membrane transport vesicle OBSOLETE. (Was not defined before being made obsolete). CHEBI:17354 16beta-hydroxy steroid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17354 UBERON:0010949 sternooccipital muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010949 sternooccipital A muscle organ that has_muscle_insertion a occipital bone and has_muscle_origin a sternum. GO:0005809 obsolete Golgi-vacuole transport vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005809 Golgi-vacuole transport vesicle OBSOLETE. (Was not defined before being made obsolete). CHEBI:17355 (S)-2-acetamido-6-oxopimelic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17355 GO:0005806 obsolete Golgi-ER transport vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005806 Golgi-ER transport vesicle OBSOLETE. (Was not defined before being made obsolete). CHEBI:17352 (R)-mandelamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17352 GO:0005807 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005807 GO:0005804 obsolete secretory vesicle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005804 secretory vesicle membrane OBSOLETE. (Was not defined before being made obsolete). CHEBI:17351 linoleic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17351 GO:0005805 obsolete ER-Golgi transport vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005805 ER-Golgi transport vesicle OBSOLETE. (Was not defined before being made obsolete). GO:0030899 calcium-dependent ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030899 Catalysis of the reaction: ATP + H2O = ADP + phosphate. This reaction requires the presence of calcium ion (Ca2+). GO:0030897 HOPS complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030897 A multimeric protein complex that associates with the vacuolar membrane, late endosomal (multivesicular body) and lysosomal membranes. HOPS is a tethering complex involved in vesicle fusion. GO:0030898 actin-dependent ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030898 actin-activated ATPase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate. This reaction requires the presence of an actin filament to accelerate release of ADP and phosphate. GO:0030895 apolipoprotein B mRNA editing enzyme complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030895 apoB mRNA editing enzyme complex|APOBEC Protein complex that mediates editing of the mRNA encoding apolipoprotein B; catalyzes the deamination of C to U (residue 6666 in the human mRNA). Contains a catalytic subunit, APOBEC-1, and other proteins (e.g. human ASP; rat ASP and KSRP). GO:0030896 checkpoint clamp complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030896 Rad9-Hus1-Rad1 (9-1-1) clamp complex|CCC Conserved heterotrimeric complex of PCNA-like proteins that is loaded onto DNA at sites of DNA damage. GO:0015256 obsolete monocarboxylate channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015256 monocarboxylate channel activity OBSOLETE. This term was not defined before being made obsolete. GO:0015257 obsolete organic anion channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015257 organic anion channel activity OBSOLETE. This term was not defined before being made obsolete. GO:0015258 obsolete gluconate channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015258 gluconate channel activity OBSOLETE. This term was not defined before being made obsolete. GO:0015259 obsolete glutamate channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015259 glutamate channel activity OBSOLETE. This term was not defined before being made obsolete. GO:0030893 meiotic cohesin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030893 A cohesin complex that mediates sister chromatid cohesion during meiosis; has a subunit composition distinct from that of the mitotic cohesin complex. GO:0015252 proton channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015252 hydrogen ion channel activity Enables the facilitated diffusion of a hydrogen ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. GO:0030894 replisome biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0030894 Wikipedia:Replisome replication-competent complex|DNA synthesome complex|RC complex A multi-component enzymatic machine at the replication fork which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins. GO:0015253 obsolete sugar/polyol channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015253 sugar/polyol channel activity OBSOLETE. (Was not defined before being made obsolete). GO:0030891 VCB complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030891 VHL complex|von Hippel-Lindau tumor suppressor complex|pVHL-elongin C-elongin B complex A protein complex that possesses ubiquitin ligase activity; the complex is usually pentameric; for example, in mammals the subunits are pVHL, elongin B, elongin C, cullin-2 (Cul2), and Rbx1. GO:0015254 glycerol channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015254 Reactome:R-HSA-507871|Reactome:R-HSA-432074|Reactome:R-HSA-432049|RHEA:29675|Reactome:R-HSA-507869 Enables the facilitated diffusion of glycerol (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. GO:0030892 mitotic cohesin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030892 A cohesin complex that mediates sister chromatid cohesion during mitosis; has a subunit composition distinct from that of the meiotic cohesin complex. GO:0015255 propanediol channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015255 Enables the facilitated diffusion of propanediol (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. GO:0030890 positive regulation of B cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030890 positive regulation of B-lymphocyte proliferation|up regulation of B cell proliferation|positive regulation of B lymphocyte proliferation|upregulation of B cell proliferation|stimulation of B cell proliferation|positive regulation of B-cell proliferation|activation of B cell proliferation|up-regulation of B cell proliferation Any process that activates or increases the rate or extent of B cell proliferation. GO:0015250 water channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015250 Reactome:R-HSA-445714|Reactome:R-HSA-432065|Reactome:R-HSA-432067|Reactome:R-HSA-507868|RHEA:29667|Reactome:R-HSA-432054|Reactome:R-HSA-432010|Reactome:R-HSA-507870 aquaporin Transport systems of this type enable facilitated diffusion of water (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. GO:0015251 ammonium channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015251 Enables the facilitated diffusion of ammonium (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. GO:0030888 regulation of B cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030888 regulation of B lymphocyte proliferation|regulation of B-cell proliferation|regulation of B-lymphocyte proliferation Any process that modulates the frequency, rate or extent of B cell proliferation. GO:0030889 negative regulation of B cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030889 downregulation of B cell proliferation|down regulation of B cell proliferation|inhibition of B cell proliferation|negative regulation of B-cell proliferation|negative regulation of B-lymphocyte proliferation|down-regulation of B cell proliferation|negative regulation of B lymphocyte proliferation Any process that stops, prevents or reduces the rate or extent of B cell proliferation. GO:0030886 negative regulation of myeloid dendritic cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030886 down regulation of myeloid dendritic cell activation|downregulation of myeloid dendritic cell activation|down-regulation of myeloid dendritic cell activation|inhibition of myeloid dendritic cell activation Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid dendritic cell activation. GO:0030887 positive regulation of myeloid dendritic cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030887 upregulation of myeloid dendritic cell activation|up regulation of myeloid dendritic cell activation|activation of myeloid dendritic cell activation|stimulation of myeloid dendritic cell activation|up-regulation of myeloid dendritic cell activation Any process that stimulates, induces or increases the rate of myeloid dendritic cell activation. GO:0030884 exogenous lipid antigen binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030884 Interacting selectively and non-covalently with an exogenous lipid antigen (examples include microbial lipids and glycolipids). GO:0030885 regulation of myeloid dendritic cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030885 Any process that modulates the frequency or rate of myeloid dendritic cell activation. GO:0015267 channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015267 TC:1|Reactome:R-HSA-3779381|Reactome:R-HSA-8953430|RHEA:29447 channel/pore class transporter activity|alpha-type channel activity|nonselective channel activity|channel-forming toxin activity|pore activity|pore class transporter activity|substrate-specific channel activity Enables the energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules. GO:0015268 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015268 GO:0015269 calcium-activated potassium channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015269 Enables the calcium concentration-regulatable energy-independent passage of potassium ions across a lipid bilayer down a concentration gradient. GO:0015263 obsolete amine/amide/polyamine channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015263 amine/amide/polyamine channel activity OBSOLETE. (Was not defined before being made obsolete). GO:0030882 lipid antigen binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030882 Interacting selectively and non-covalently with a lipid antigen. GO:0015264 methylammonium channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015264 Enables the facilitated diffusion of methylammonium (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. Methylammonium is CH3NH2. GO:0030883 endogenous lipid antigen binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030883 Interacting selectively and non-covalently with an endogenous cellular lipid antigen. GO:0015265 urea channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015265 Reactome:R-HSA-507875|Reactome:R-HSA-507873 Enables the facilitated diffusion of urea (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. GO:0030880 RNA polymerase complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0030880 multisubunit RNA polymerase Any complex that possesses RNA polymerase activity; generally comprises a catalytic subunit and one or more additional subunits. GO:0015266 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015266 GO:0030881 beta-2-microglobulin binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0030881 Interacting selectively and non-covalently with beta-2-microglobulin. GO:0015260 obsolete isethionate channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015260 isethionate channel activity OBSOLETE. This term was not defined before being made obsolete. GO:0015261 obsolete lactate channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015261 lactate channel activity OBSOLETE. This term was not defined before being made obsolete. GO:0015262 obsolete taurine channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015262 taurine channel activity OBSOLETE. This term was not defined before being made obsolete. GO:0030879 mammary gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030879 mammogenesis The process whose specific outcome is the progression of the mammary gland over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. Its development starts with the formation of the mammary line and ends as the mature gland cycles between nursing and weaning stages. GO:0030877 beta-catenin destruction complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030877 APC-Axin-1-beta-catenin complex|Axin-APC-beta-catenin-GSK3B complex|beta-catenin degradation complex|23S APC complex|BDC A cytoplasmic protein complex containing glycogen synthase kinase-3-beta (GSK-3-beta), the adenomatous polyposis coli protein (APC), and the scaffolding protein axin, among others; phosphorylates beta-catenin, targets it for degradation by the proteasome. GO:0030878 thyroid gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030878 The process whose specific outcome is the progression of the thyroid gland over time, from its formation to the mature structure. The thyroid gland is an endoderm-derived gland that produces thyroid hormone. GO:0030875 rDNA protrusion biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030875 ribosomal DNA protrusion Any of the tandem arrays of rDNA localized at the periphery of the nucleus and protruding into the nucleolus, and associated proteins. May be visible as a single or double spot by DAPI staining. GO:0030876 interleukin-20 receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030876 IL-20 receptor complex A protein complex composed of an alpha and a beta receptor subunit and an interleukin ligand. In human, Interleukin-19, -20 and -24 bind IL20RA/IL20RB receptor subunits and Interleukin-20 and -24 bind IL22RA1/IL20RB receptor subunits. GO:0030873 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030873 GO:0030874 nucleolar chromatin biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030874 The portion of nuclear chromatin associated with the nucleolus; includes the DNA encoding the ribosomal RNA. GO:0015238 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015238 GO:0015239 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015239 GO:0015234 thiamine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015234 RHEA:34919|Reactome:R-HSA-199626 vitamin B1 transporter activity|thiamin uptake transporter activity|thiamin transmembrane transporter activity|thiamin permease activity|thiamine uptake transmembrane transporter activity|thiamine permease activity Enables the transfer of thiamine from one side of a membrane to the other. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver. GO:0015235 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015235 GO:0015236 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015236 GO:0015237 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015237 GO:0015230 FAD transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015230 flavin adenine dinucleotide carrier activity|flavin-adenine dinucleotide transmembrane transporter activity|FAD carrier activity|FAD transporter activity|flavin-adenine dinucleotide carrier activity|flavin adenine dinucleotide transmembrane transporter activity Enables the directed movement of flavin-adenine dinucleotide (FAD) from one side of a membrane to the other. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form. GO:0030871 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030871 GO:0015231 5-formyltetrahydrofolate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015231 5-formyltetrahydrofolate transporter activity Enables the transfer of 5-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate, from one side of a membrane to the other. GO:0030872 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030872 GO:0015232 heme transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015232 Reactome:R-HSA-917870|Reactome:R-HSA-9661408|Reactome:R-HSA-917892 heme transporter activity|haem transporter activity Enables the transfer of heme from one side of a membrane to the other. GO:0030870 Mre11 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030870 RAD50-MRE11-NBN complex|RMX complex|MRX complex|Rad50 complex|MRN complex|Rad50-Rad32-Nbs1 complex Trimeric protein complex that possesses endonuclease activity; involved in meiotic recombination, DNA repair and checkpoint signaling. In Saccharomyces cerevisiae, the complex comprises Mre11p, Rad50p, and Xrs2p; complexes identified in other species generally contain proteins orthologous to the Saccharomyces cerevisiae proteins. GO:0015233 pantothenate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015233 pantothenate transporter activity|vitamin B5 transmembrane transporter activity Enables the directed movement of pantothenate across a membrane. Pantothenate is the anion of pantothenic acid, the amide of beta-alanine and pantoic acid; it is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods. GO:0030868 smooth endoplasmic reticulum membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030868 NIF_Subcellular:sao1596955044 smooth ER membrane|SER membrane The lipid bilayer surrounding the smooth endoplasmic reticulum. GO:0030869 RENT complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030869 A protein complex that mediates transcriptional silencing at the rDNA locus (the name derives from regulator of nucleolar silencing and telophase). In Saccharomyces the complex contains Net1p, Sir2p, Cdc14p, and at least one more subunit. GO:0030866 cortical actin cytoskeleton organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030866 cortical actin cytoskeleton organisation|cortical actin cytoskeleton organization and biogenesis|cortical resistance|cortical actin cytoskeleton stabilization|actin cortex stabilization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of actin-based cytoskeletal structures in the cell cortex, i.e. just beneath the plasma membrane. GO:0030867 rough endoplasmic reticulum membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030867 NIF_Subcellular:sao3089754107 rough ER membrane|RER membrane The lipid bilayer surrounding the rough endoplasmic reticulum. GO:0030864 cortical actin cytoskeleton biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030864 The portion of the actin cytoskeleton, comprising filamentous actin and associated proteins, that lies just beneath the plasma membrane. GO:0030865 cortical cytoskeleton organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030865 cortical cytoskeleton organization and biogenesis|cortical cytoskeleton organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures in the cell cortex, i.e. just beneath the plasma membrane. GO:0030862 positive regulation of polarized epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030862 up regulation of polarized epithelial cell differentiation|activation of polarized epithelial cell differentiation|stimulation of polarized epithelial cell differentiation|up-regulation of polarized epithelial cell differentiation|upregulation of polarized epithelial cell differentiation Any process that activates or increases the rate or extent of polarized epithelial cell differentiation. GO:0030863 cortical cytoskeleton biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030863 The portion of the cytoskeleton that lies just beneath the plasma membrane. GO:0015249 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015249 GO:0015245 fatty acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015245 Reactome:R-HSA-879585|Reactome:R-HSA-5627891 fatty acyl transporter activity|peroxisomal fatty acyl transporter|fatty acid transporter activity|fatty-acyl group transporter activity Enables the transfer of fatty acids from one side of a membrane to the other. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis. GO:0015246 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015246 GO:0015247 aminophospholipid flippase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015247 aminophospholipid transmembrane transporter activity|aminophospholipid transporter activity Enables the transfer of aminophospholipids from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP. Aminophospholipids contain phosphoric acid as a mono- or diester and an amino (NH2) group. GO:0015248 sterol transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015248 Reactome:R-HSA-8867667|Reactome:R-HSA-5250531|Reactome:R-HSA-8868402|Reactome:R-HSA-5679101|Reactome:R-HSA-265783|Reactome:R-HSA-5679145|RHEA:39747 Enables the directed movement of sterols into, out of or within a cell, or between cells. Sterol are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. GO:0030860 regulation of polarized epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030860 Any process that modulates the frequency, rate or extent of polarized epithelial cell differentiation. GO:0015241 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015241 GO:0030861 negative regulation of polarized epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030861 downregulation of polarized epithelial cell differentiation|down-regulation of polarized epithelial cell differentiation|inhibition of polarized epithelial cell differentiation|down regulation of polarized epithelial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of polarized epithelial cell differentiation. GO:0015242 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015242 GO:0015243 cycloheximide transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015243 cycloheximide transporter activity Enables the transfer of cycloheximide from one side of a membrane to the other. Cycloheximide is an antibiotic produced by Streptomyces which interferes with protein synthesis in eukaryotes. GO:0015244 fluconazole transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015244 fluconazole transporter activity Enables the transfer of fluconazole from one side of a membrane to the other. Fluconazole is an antifungal drug used for oral candidiasis and cryptococcal meningitis; it is still under study for treatment of vaginal candidiasis and other fungal infections. GO:0015240 amiloride transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015240 amiloride transporter activity Enables the transfer of amiloride from one side of a membrane to the other. Amiloride is a potent and specific inhibitor of sodium ion entry into cells. It is used as a potassium-sparing diuretic. GO:0030857 negative regulation of epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030857 downregulation of epithelial cell differentiation|down-regulation of epithelial cell differentiation|inhibition of epithelial cell differentiation|down regulation of epithelial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell differentiation. GO:0030858 positive regulation of epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030858 up regulation of epithelial cell differentiation|activation of epithelial cell differentiation|stimulation of epithelial cell differentiation|up-regulation of epithelial cell differentiation|upregulation of epithelial cell differentiation Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation. GO:0005899 insulin receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005899 A disulfide-bonded, heterotetrameric receptor complex. The alpha chains are entirely extracellular, while each beta chain has one transmembrane domain. The ligand binds to the alpha subunit extracellular domain and the kinase is associated with the beta subunit intracellular domain. GO:0030855 epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030855 The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium. GO:0030856 regulation of epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030856 Any process that modulates the frequency, rate or extent of epithelial cell differentiation. GO:0005897 interleukin-9 receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005897 IL-9 receptor complex A protein complex that binds interleukin-9; comprises an alpha and a beta subunit. The alpha chain is specific to the interleukin-9 receptor, whereas the beta chain is shared with the receptors for several other interleukins. GO:0030853 negative regulation of granulocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030853 downregulation of granulocyte differentiation|down-regulation of granulocyte differentiation|inhibition of granulocyte differentiation|down regulation of granulocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of granulocyte differentiation. GO:0005898 interleukin-13 receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005898 IL-13 receptor complex A protein complex that binds interleukin-13; consists of two chains, interleukin-13 receptor alpha1 chain and interleukin-4 receptor alpha chain. GO:0030854 positive regulation of granulocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030854 up regulation of granulocyte differentiation|activation of granulocyte differentiation|stimulation of granulocyte differentiation|up-regulation of granulocyte differentiation|upregulation of granulocyte differentiation Any process that activates or increases the frequency, rate or extent of granulocyte differentiation. GO:0005895 interleukin-5 receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005895 IL-5 receptor complex A protein complex that binds interleukin-3; comprises an alpha and a beta subunit. The alpha chain is specific to the interleukin-5 receptor, whereas the beta chain is shared with the receptors for granulocyte-macrophage colony-stimulating factor and interleukin-3. GO:0030851 granulocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030851 granulocyte cell differentiation The process in which a myeloid precursor cell acquires the specialized features of a granulocyte. Granulocytes are a class of leukocytes characterized by the presence of granules in their cytoplasm. These cells are active in allergic immune reactions such as arthritic inflammation and rashes. This class includes basophils, eosinophils and neutrophils. GO:0030852 regulation of granulocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030852 Any process that modulates the frequency, rate or extent of granulocyte differentiation. GO:0005896 interleukin-6 receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005896 IL-6 receptor complex A hexameric protein complex consisting of two molecules each of interleukin-6, interleukin-6 receptor alpha chain, and gp-130. GO:0005893 interleukin-2 receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005893 IL-2 receptor complex A protein complex that binds interleukin-2; comprises alpha, beta, and gamma subunits. UBERON:0009906 root of optic nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009906 optic nerve root|optic tract root|root of optic tract A nerve root that extends_fibers_into a nerve connecting eye with brain. GO:0005894 interleukin-3 receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005894 IL-3 receptor complex A protein complex that binds interleukin-3; comprises an alpha and a beta subunit. The alpha chain is specific to the interleukin-3 receptor, whereas the beta chain is shared with the receptors for granulocyte-macrophage colony-stimulating factor and interleukin-5. GO:0005891 voltage-gated calcium channel complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0005891 voltage-sensitive calcium channel complex|voltage gated calcium channel complex|voltage-dependent calcium channel complex A protein complex that forms a transmembrane channel through which calcium ions may pass in response to changes in membrane potential. GO:0005892 acetylcholine-gated channel complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005892 nicotinic acetylcholine receptor|nicotinic acetylcholine-gated receptor-channel complex A homo- or hetero-pentameric protein complex that forms a transmembrane channel through which ions may pass in response to acetylcholine binding. GO:0005890 sodium:potassium-exchanging ATPase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005890 sodium pump|sodium/potassium-exchanging ATPase complex Sodium:potassium-exchanging ATPases are tetrameric proteins, consisting of two large alpha subunits and two smaller beta subunits. The alpha subunits bear the active site and penetrate the membrane, while the beta subunits carry oligosaccharide groups and face the cell exterior. GO:0030859 polarized epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030859 The process in which a relatively unspecialized cell acquires specialized features of a polarized epithelial cell. The polarized epithelial cell can be any of the cells within an epithelium where the epithelial sheet is oriented with respect to the planar axis. CHEBI:42394 tricosanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_42394 GO:0015216 purine nucleotide transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015216 Enables the transfer of a purine nucleotide, any compound consisting of a purine nucleoside esterified with (ortho)phosphate, from one side of a membrane to the other. GO:0015217 ADP transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015217 Enables the transfer of ADP, adenosine diphosphate, from one side of a membrane to the other. GO:0015218 pyrimidine nucleotide transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015218 Enables the transfer of a pyrimidine nucleotide, any compound consisting of a pyrimidine nucleoside esterified with (ortho)phosphate, from one side of a membrane to the other. UBERON:0009911 lobule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009911 lobulus UBERON:0009912 anatomical lobe biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009912 lobus A portion of an organ, such as the liver, lung, breast, or brain. GO:0015219 obsolete protein-DNA complex transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015219 DNA-protein complex transmembrane transporter activity OBSOLETE. Enables the transfer of protein-DNA complexes from one side of a membrane to the other. UBERON:0009913 renal lobe biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009913 lobi renalis|lobi renales|lobus renalis|kidney lobe The portion of a kidney consisting of a renal medullary pyramid and the renal cortex above it[MP]. It is composed of many renal lobules[WP]. GO:0015212 cytidine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015212 Enables the transfer of cytidine, cytosine riboside, from one side of a membrane to the other. UBERON:0009914 renal lobule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009914 renunculus|renal cortical lobule|cortical lobule of kidney|renculus|cortical lobule|lobulus corticalis renalis|kidney lobule|lobuli corticales renis|reniculus|lobulus renalis The portion of a renal lobe consisting of nephrons grouped around a single medullary ray and draining into a single collecting duct; human kidneys have multilobular, multipapillary architecture while mice and rats have unilobular, unipapillary kidneys GO:0015213 uridine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015213 uracil/uridine permease activity Enables the transfer of uridine, uracil riboside, from one side of a membrane to the other. GO:0015214 pyrimidine nucleoside transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015214 Enables the transfer of a pyrimidine nucleoside, a pyrimidine base covalently bonded to a ribose or deoxyribose sugar from one side of a membrane to the other. UBERON:0009916 wall of ureter biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009916 ureteral wall An anatomical wall that is part of a ureter. GO:0015215 nucleotide transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015215 Enables the transfer of a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate, from one side of a membrane to the other. GO:0030850 prostate gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030850 prostate development The process whose specific outcome is the progression of the prostate gland over time, from its formation to the mature structure. The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid. GO:0015210 uracil transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015210 uracil/uridine permease activity Enables the transfer of uracil, 2,4-dioxopyrimidine, from one side of a membrane to the other. GO:0015211 purine nucleoside transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015211 Enables the transfer of a purine nucleoside, a purine base covalently bonded to a ribose or deoxyribose sugar, from one side of a membrane to the other. GO:0030846 termination of RNA polymerase II transcription, poly(A)-coupled biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030846 transcription termination from Pol II promoter, RNA polymerase(A) coupled|termination of RNA polymerase II transcription, polyadenylation-coupled|transcription termination from Pol II promoter, poly(A) coupled The process in which transcription of polyadenylated RNA polymerase II transcripts is terminated; cleavage and polyadenylylation of the mRNA 3' end is coupled to transcription termination. GO:0030847 termination of RNA polymerase II transcription, exosome-dependent biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030847 transcription termination from Pol II promoter, poly(A)-independent|termination of RNA polymerase II transcription, poly(A)-independent|transcription termination from Pol II promoter, RNA polymerase(A)-independent The process in which transcription of nonpolyadenylated RNA polymerase II transcripts is terminated; coupled to the maturation of the RNA 3'-end. GO:0030844 positive regulation of intermediate filament depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030844 upregulation of intermediate filament depolymerization|positive regulation of intermediate filament polymerization and/or depolymerization|stimulation of intermediate filament depolymerization|up-regulation of intermediate filament depolymerization|activation of intermediate filament depolymerization|up regulation of intermediate filament depolymerization Any process that activates or increases the frequency, rate or extent of intermediate filament depolymerization. GO:0030845 phospholipase C-inhibiting G protein-coupled receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030845 phospholipase C inhibition|inhibition of phospholipase C activity involved in G-protein coupled receptor signalling pathway|G-protein-coupled inhibitory pathway of phospholipase C|GPCR signaling pathway via inhibition of PLC|GPCR signaling pathway coupled to inhibition of phospholipase C activity|phospholipase C-inhibiting G-protein coupled receptor signaling pathway|PLC-inhibiting GPCR signaling pathway A G protein-coupled receptor signaling pathway which proceeds with inhibition of phospholipase C (PLC) activity and a subsequent decrease in the levels of cellular inositol trisphosphate (IP3) and diacylglycerol (DAG). GO:0030842 regulation of intermediate filament depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030842 Any process that modulates the frequency, rate or extent of the disassembly of intermediate filaments by the removal of monomers from a filament. GO:0030843 negative regulation of intermediate filament depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030843 inhibition of intermediate filament depolymerization|negative regulation of intermediate filament polymerization and/or depolymerization|down-regulation of intermediate filament depolymerization|downregulation of intermediate filament depolymerization|down regulation of intermediate filament depolymerization Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate filament depolymerization. GO:0030840 negative regulation of intermediate filament polymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030840 inhibition of intermediate filament polymerization|negative regulation of intermediate filament polymerization and/or depolymerization|down-regulation of intermediate filament polymerization|downregulation of intermediate filament polymerization|down regulation of intermediate filament polymerization Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate filament polymerization. GO:0030841 positive regulation of intermediate filament polymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030841 upregulation of intermediate filament polymerization|positive regulation of intermediate filament polymerization and/or depolymerization|stimulation of intermediate filament polymerization|activation of intermediate filament polymerization|up-regulation of intermediate filament polymerization|up regulation of intermediate filament polymerization Any process that activates or increases the frequency, rate or extent of intermediate filament polymerization. GO:0030848 threo-3-hydroxyaspartate ammonia-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030848 MetaCyc:4.3.1.16-RXN|EC:4.3.1.16|KEGG_REACTION:R05758|RHEA:12424 threo-3-hydroxy-L-aspartate ammonia-lyase activity|threo-3-hydroxy-L-aspartate ammonia-lyase (oxaloacetate-forming)|3-hydroxyaspartate dehydratase activity|threo-3-hydroxyaspartate dehydratase activity|L-threo-3-hydroxyaspartate dehydratase activity Catalysis of the reaction: (3S)-3-hydroxy-L-aspartate = NH(4)(+) + oxaloacetate. GO:0030849 autosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030849 Wikipedia:Autosome Any chromosome other than a sex chromosome. GO:0015227 acyl carnitine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015227 Reactome:R-HSA-200424 acylcarnitine transporter activity Enables the transfer of acyl carnitine from one side of a membrane to the other. Acyl carnitine is the condensation product of a carboxylic acid and carnitine and is the transport form for a fatty acid crossing the mitochondrial membrane. GO:0015228 coenzyme A transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015228 coenzyme A transporter activity Enables the transfer of coenzyme A from one side of a membrane to the other. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester. GO:0015229 L-ascorbic acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015229 Reactome:R-HSA-198870 vitamin C transporter activity|L-ascorbate transporter activity Enables the transfer of L-ascorbate from one side of a membrane to the other. L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, is vitamin C and has co-factor and anti-oxidant activities in many species. GO:0015223 obsolete vitamin or cofactor transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015223 vitamin/cofactor transporter activity|vitamin or cofactor transporter activity OBSOLETE. Enables the directed transport of vitamins or cofactors into, out of or within a cell, or between cells. GO:0015224 biopterin transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015224 biopterin transporter activity Enables the transfer of biopterin from one side of a membrane to the other. Biopterin is a growth factor for certain protozoans and some insects; it is widely distributed in tissues and functions in a reduced form, tetrahydrobiopterin, as a hydroxylation coenzyme. GO:0015225 biotin transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015225 RHEA:28458 biotin transporter activity|vitamin H transporter activity|vitamin B7 transporter activity Enables the transfer of biotin from one side of a membrane to the other. Biotin is cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions. GO:0015226 carnitine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015226 Reactome:R-HSA-549297|Reactome:R-HSA-164967|Reactome:R-HSA-5625674|Reactome:R-HSA-165026 vitamin Bt transporter activity Enables the transfer of carnitine across a membrane. Carnitine is a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane. GO:0015220 choline transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015220 Reactome:R-HSA-444433|Reactome:R-HSA-6797956|Reactome:R-HSA-5658483|Reactome:R-HSA-429594 amino acid/choline transmembrane transporter activity|choline permease activity Enables the transfer of choline from one side of a membrane to the other. Choline (2-hydroxyethyltrimethylammonium) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine. GO:0015221 lipopolysaccharide transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015221 LPS transmembrane transporter activity Enables the transfer of lipopolysaccharides from one side of a membrane to the other. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide. GO:0015222 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015222 GO:0030835 negative regulation of actin filament depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030835 down-regulation of actin filament depolymerization|inhibition of actin filament depolymerization|negative regulation of actin polymerization and/or depolymerization|down regulation of actin filament depolymerization|downregulation of actin filament depolymerization|actin filament stabilization|negative regulation of actin depolymerization Any process that stops, prevents, or reduces the frequency, rate or extent of actin depolymerization. GO:0005879 axonemal microtubule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005879 A microtubule in the axoneme of a eukaryotic cilium or flagellum; an axoneme contains nine modified doublet microtubules, which may or may not surround a pair of single microtubules. GO:0030836 positive regulation of actin filament depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030836 actin filament destabilization|stimulation of actin filament depolymerization|positive regulation of actin depolymerization|up-regulation of actin filament depolymerization|positive regulation of actin polymerization and/or depolymerization|upregulation of actin filament depolymerization|up regulation of actin filament depolymerization|activation of actin filament depolymerization Any process that activates or increases the frequency, rate or extent of actin depolymerization. GO:0030833 regulation of actin filament polymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030833 regulation of actin polymerization Any process that modulates the frequency, rate or extent of the assembly of actin filaments by the addition of actin monomers to a filament. GO:0030834 regulation of actin filament depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030834 regulation of actin depolymerization Any process that modulates the frequency, rate or extent of the disassembly of actin filaments by the removal of actin monomers from a filament. GO:0030831 obsolete positive regulation of cGMP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030831 upregulation of cGMP catabolic process|positive regulation of cGMP catabolism|stimulation of cGMP catabolic process|up-regulation of cGMP catabolic process|activation of cGMP catabolic process|positive regulation of cGMP degradation|positive regulation of cGMP breakdown|up regulation of cGMP catabolic process OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cGMP. GO:0005875 microtubule associated complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005875 Any multimeric complex connected to a microtubule. GO:0005876 spindle microtubule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005876 Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole. GO:0030832 regulation of actin filament length biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030832 Any process that controls the length of actin filaments in a cell. GO:0005873 plus-end kinesin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005873 Any complex that includes a dimer of molecules from the kinesin superfamily and any associated proteins, and moves towards the plus end of a microtubule. GO:0005874 microtubule biolink:CellularComponent go-plus goslim_metagenomics http://purl.obolibrary.org/obo/GO_0005874 Wikipedia:Microtubule|NIF_Subcellular:sao1846835077 neurotubule|microtubuli|microtubulus Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle. GO:0030830 obsolete negative regulation of cGMP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030830 downregulation of cGMP catabolic process|down regulation of cGMP catabolic process|inhibition of cGMP catabolic process|negative regulation of cGMP degradation|negative regulation of cGMP catabolism|negative regulation of cGMP breakdown|down-regulation of cGMP catabolic process OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cGMP. GO:0005871 kinesin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005871 Any complex that includes a dimer of molecules from the kinesin superfamily, a group of related proteins that contain an extended region of predicted alpha-helical coiled coil in the main chain that likely produces dimerization. The native complexes of several kinesin family members have also been shown to contain additional peptides, often designated light chains as all of the noncatalytic subunits that are currently known are smaller than the chain that contains the motor unit. Kinesin complexes generally possess a force-generating enzymatic activity, or motor, which converts the free energy of the gamma phosphate bond of ATP into mechanical work. GO:0005872 minus-end kinesin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005872 Any complex that includes a dimer of molecules from the kinesin superfamily and any associated proteins, and moves towards the minus end of a microtubule. GO:0005870 actin capping protein of dynactin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005870 A heterodimer consisting of alpha and beta subunits that binds to and caps the barbed ends of actin filaments, nucleates the polymerization of actin monomers but does not sever actin filaments, and which is a part of the dynactin complex. GO:0030839 regulation of intermediate filament polymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030839 Any process that modulates the frequency, rate or extent of the assembly of intermediate filaments by the addition of monomers to a filament. GO:0030837 negative regulation of actin filament polymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030837 negative regulation of actin polymerization|down-regulation of actin filament polymerization|inhibition of actin filament polymerization|negative regulation of actin polymerization and/or depolymerization|down regulation of actin filament polymerization|downregulation of actin filament polymerization Any process that stops, prevents, or reduces the frequency, rate or extent of actin polymerization. GO:0030838 positive regulation of actin filament polymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030838 activation of actin filament polymerization|stimulation of actin filament polymerization|positive regulation of actin polymerization|up-regulation of actin filament polymerization|positive regulation of actin polymerization and/or depolymerization|upregulation of actin filament polymerization|up regulation of actin filament polymerization Any process that activates or increases the frequency, rate or extent of actin polymerization. GO:0030824 obsolete negative regulation of cGMP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030824 down-regulation of cGMP metabolic process|negative regulation of cGMP metabolism|downregulation of cGMP metabolic process|down regulation of cGMP metabolic process|inhibition of cGMP metabolic process OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving cGMP. GO:0030825 obsolete positive regulation of cGMP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030825 activation of cGMP metabolic process|positive regulation of cGMP metabolism|up regulation of cGMP metabolic process|upregulation of cGMP metabolic process|stimulation of cGMP metabolic process|up-regulation of cGMP metabolic process OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving cGMP. GO:0030822 obsolete positive regulation of cAMP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030822 upregulation of cAMP catabolic process|stimulation of cAMP catabolic process|up-regulation of cAMP catabolic process|activation of cAMP catabolic process|positive regulation of cAMP degradation|positive regulation of 3',5' cAMP catabolism|positive regulation of cAMP breakdown|positive regulation of 3',5'-cAMP catabolic process|positive regulation of cyclic AMP catabolism|positive regulation of adenosine 3',5'-cyclophosphate catabolic process|up regulation of cAMP catabolic process|positive regulation of cAMP catabolism|positive regulation of adenosine 3',5'-cyclophosphate catabolism|positive regulation of cyclic AMP catabolic process|positive regulation of 3',5'-cAMP catabolism|positive regulation of 3',5' cAMP catabolic process OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate). GO:0005888 obsolete proteoglycan integral to plasma membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005888 proteoglycan integral to plasma membrane OBSOLETE. Penetrating at least one phospholipid bilayer of a plasma membrane and consisting of proteoglycan. Also refers to the state of being buried in the bilayer with no exposure outside the bilayer. GO:0005889 potassium:proton exchanging ATPase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005889 hydrogen/potassium-exchanging ATPase complex|proton pump|hydrogen:potassium-exchanging ATPase complex A protein complex that possesses hydrogen:potassium-exchanging ATPase activity; characterized in animal cells, where it maintains ionic gradients of K+ at the expense of ATP hydrolysis; The complex contains two obligatory subunits, the catalytic alpha subunit and a glycosylated beta subunit; two additional subunits, gamma and channel-inducing factor (CHIF), may also be present. GO:0030823 obsolete regulation of cGMP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030823 regulation of cGMP metabolism OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving cGMP. GO:0005886 plasma membrane biolink:CellularComponent go-plus goslim_generic|goslim_chembl|goslim_mouse|goslim_agr|goslim_candida|goslim_yeast|goslim_plant|goslim_drosophila|goslim_metagenomics|goslim_aspergillus http://purl.obolibrary.org/obo/GO_0005886 Wikipedia:Cell_membrane|NIF_Subcellular:sao1663586795 cellular membrane|inner endospore membrane|cell membrane|bacterial inner membrane|cytoplasmic membrane|plasma membrane lipid bilayer|plasmalemma|juxtamembrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0030820 obsolete regulation of cAMP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030820 regulation of 3',5' cAMP catabolic process|regulation of 3',5' cAMP catabolism|regulation of cyclic AMP catabolism|regulation of cAMP catabolism|regulation of adenosine 3',5'-cyclophosphate catabolism|regulation of cAMP degradation|regulation of 3',5'-cAMP catabolism|regulation of cAMP breakdown|regulation of 3',5'-cAMP catabolic process|regulation of adenosine 3',5'-cyclophosphate catabolic process|regulation of cyclic AMP catabolic process OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate). GO:0030821 obsolete negative regulation of cAMP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030821 negative regulation of 3',5'-cAMP catabolism|negative regulation of cAMP degradation|negative regulation of cAMP breakdown|negative regulation of 3',5'-cAMP catabolic process|down-regulation of cAMP catabolic process|negative regulation of adenosine 3',5'-cyclophosphate catabolic process|negative regulation of 3',5' cAMP catabolism|negative regulation of cyclic AMP catabolic process|negative regulation of cyclic AMP catabolism|downregulation of cAMP catabolic process|negative regulation of 3',5' cAMP catabolic process|negative regulation of adenosine 3',5'-cyclophosphate catabolism|negative regulation of cAMP catabolism|down regulation of cAMP catabolic process|inhibition of cAMP catabolic process OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate). GO:0005887 integral component of plasma membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005887 integral to plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0005884 actin filament biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005884 FMA:63850|Wikipedia:Actin|NIF_Subcellular:sao1588493326 microfilament A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane. GO:0005885 Arp2/3 protein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005885 A stable protein complex that contains two actin-related proteins, Arp2 and Arp3, and five novel proteins (ARPC1-5), and functions in the nucleation of branched actin filaments. GO:0005882 intermediate filament biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005882 Wikipedia:Intermediate_filament|FMA:63851|NIF_Subcellular:sao952483289 intermediate filament associated protein|type I intermediate filament associated protein|type II intermediate filament associated protein A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filaments; and Type V, lamins. GO:0005883 neurofilament biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005883 NIF_Subcellular:sao1316272517|Wikipedia:Neurofilament type IV intermediate filament A type of intermediate filament found in the core of neuronal axons. Neurofilaments are heteropolymers composed of three type IV polypeptides: NF-L, NF-M, and NF-H (for low, middle, and high molecular weight). Neurofilaments are responsible for the radial growth of an axon and determine axonal diameter. GO:0005880 nuclear microtubule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005880 Any microtubule in the nucleus of a cell. GO:0005881 cytoplasmic microtubule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005881 non-spindle-associated astral microtubule Any microtubule in the cytoplasm of a cell. GO:0030828 obsolete positive regulation of cGMP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030828 up regulation of cGMP biosynthetic process|activation of cGMP biosynthetic process|positive regulation of cGMP biosynthesis|stimulation of cGMP biosynthetic process|up-regulation of cGMP biosynthetic process|positive regulation of cGMP anabolism|upregulation of cGMP biosynthetic process|positive regulation of cGMP synthesis|positive regulation of cGMP formation OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cGMP. GO:0015209 cytosine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015209 Enables the transfer of cytosine, 4-amino-2-hydroxypyrimidine from one side of a membrane to the other. GO:0030829 obsolete regulation of cGMP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030829 regulation of cGMP degradation|regulation of cGMP breakdown|regulation of cGMP catabolism OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cGMP. FAO:0002002 multicellular fungal structure biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/FAO_0002002 A fungal structure that comprises more than one cell. GO:0030826 obsolete regulation of cGMP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030826 regulation of cGMP synthesis|regulation of cGMP formation|regulation of cGMP anabolism|regulation of cGMP biosynthesis OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cGMP. GO:0030827 obsolete negative regulation of cGMP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030827 negative regulation of cGMP biosynthesis|down-regulation of cGMP biosynthetic process|inhibition of cGMP biosynthetic process|negative regulation of cGMP anabolism|negative regulation of cGMP synthesis|negative regulation of cGMP formation|down regulation of cGMP biosynthetic process|downregulation of cGMP biosynthetic process OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cGMP. FAO:0002004 multicellular fungal structure, multicellular organism biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/FAO_0002004 multicellular structure, multicellular organism A multicellular fungal structure composed of two or more cells of a single multicellular organism. CHEBI:42362 (6E,10E)-2,6,10-trimethyldodeca-2,6,10-triene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_42362 GO:0015205 nucleobase transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015205 Enables the transfer of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acidfrom one side of a membrane to the other. GO:0015206 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015206 GO:0015207 adenine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015207 RHEA:34999|Reactome:R-HSA-5672027|Reactome:R-HSA-163215 Enables the transfer of adenine, 6-aminopurine, from one side of a membrane to the other. GO:0015208 guanine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015208 Enables the transfer of guanine, 2-amino-6-hydroxypurine, from one side of a membrane to the other. GO:0015201 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015201 GO:0015202 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015202 GO:0015203 polyamine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015203 amine/amide/polyamine channel activity Enables the transfer of polyamines, organic compounds containing two or more amino groups, from one side of a membrane to the other. GO:0015204 urea transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015204 RHEA:32799|Reactome:R-HSA-444126 urea transporter activity Enables the transfer of urea from one side of a membrane to the other. Urea is the water soluble compound H2N-CO-NH2. GO:0015200 methylammonium transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015200 Enables directed movement of methylammonium, CH3NH2, from one side of a membrane to the other. CHEBI:6331 erythro-4-hydroxy-L-glutamate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_6331 OBA:VT0000832 thalamus morphology trait biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_VT0000832 morphology of dorsal plus ventral thalamus The morphology of a dorsal plus ventral thalamus. GO:0015399 primary active transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015399 TC:3 primary active transporter Enables the transfer of a solute from one side of a membrane to the other, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is powered by a primary energy source, directly using ATP. Primary energy sources known to be coupled to transport are chemical, electrical and solar sources. GO:0015395 nucleoside transmembrane transporter activity, down a concentration gradient biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015395 equilibrative nucleoside transmembrane transporter, nitrobenzyl-thioinosine-sensitive activity|equilibrative nucleoside transporter activity|equilibrative nucleoside transmembrane transporter, nitrobenzyl-thioinosine-insensitive activity Enables the transfer of a nucleoside, from one side of a membrane to the other, down the concentration gradient. GO:0015396 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015396 GO:0015397 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015397 GO:0015398 high-affinity secondary active ammonium transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015398 high affinity secondary active ammonium transmembrane transporter activity Enables the transfer of ammonium from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. GO:0015391 nucleobase:cation symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015391 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nucleobase(out) + cation(out) = nucleobase(in) + cation(in). GO:0015392 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015392 GO:0015393 obsolete uracil/uridine permease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015393 uracil/uridine permease activity OBSOLETE. (Was not defined before being made obsolete). GO:0015394 uridine:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015394 uridine:hydrogen ion symporter activity|nucleoside (uridine) permease activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: uridine(out) + H+(out) = uridine(in) + H+(in). UBERON:0034994 hindbrain cortical intermediate zone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034994 hindbrain mantle layer UBERON:0034995 jaw mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034995 Mesenchyme that is part of a developing jaw [Automatically generated definition]. UBERON:0034996 outer renal medulla loop of Henle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034996 loop of Henle, outer medullary portion CHEBI:17309 pectin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17309 CHEBI:17307 dTDP-6-deoxy-L-talose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17307 CHEBI:17308 2-oxohexanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17308 CHEBI:17305 2-dehydro-3-deoxy-D-glucaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17305 CHEBI:17306 maltose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17306 CHEBI:32940 hexacosane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32940 CHEBI:17303 morphine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17303 CHEBI:17304 piperitenone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17304 CHEBI:17301 glucaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17301 CHEBI:17302 pentadecanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17302 CHEBI:17300 tetrachloroethene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17300 UBERON:0020358 accessory XI nerve nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0020358 nucleus nervi accessorii|nucleus accessorius columnae anterioris medullae spinalis|accessory neural nucleus|nucleus of accessory nerve|accessory nucleus of anterior column of spinal cord|nucleus of the spinal accessory nerve|spinal accessory nucleus|nucleus of the accessory nerve The spinal accessory nucleus lies within the cervical spinal cord (C1-C5) in the ventral horn. The nucleus ambiguus is classically said to provide the 'cranial component' of the accessory nerve. However, the very existence of this cranial component has been recently questioned and seen as contributing exclusively to the vagus nerve. The terminology continues to be used in describing both human anatomy, and that of other animals. CHEBI:91230 2',2'-dihydroxy-2-oxospirilloxanthin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91230 CHEBI:32955 epoxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32955 CHEBI:32957 lysophosphatidic acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32957 CHEBI:32958 phosphate group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32958 UBERON:0034997 renal medulla loop of Henle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034997 loop of Henle, medullary portion|loop of Henle of renal medulla CHEBI:32952 amine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32952 CHEBI:91235 19-(4-hydroxyphenyl)nonadecanoyl-AMP(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91235 CHEBI:91236 19-(4-hydroxyphenyl)nonadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91236 CHEBI:91232 2-amino-3-hydroxy-4-methylbenzoyl-AMP(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91232 CHEBI:91233 17-(4-hydroxyphenyl)heptadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91233 CHEBI:91234 17-(4-hydroxyphenyl)heptadecanoyl-AMP(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91234 CHEBI:32922 (1S,2R)-3-phenylcyclohexa-3,5-diene-1,2-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32922 CHEBI:32926 octadecane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32926 CHEBI:17329 UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-N(6)-(L-alanyl)-L-lysyl-D-alanyl-D-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17329 CHEBI:17327 phytol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17327 CHEBI:17328 N(6)-[(indol-3-yl)acetyl]-L-lysine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17328 CHEBI:17325 3-hydroxy-3-methylglutarate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17325 CHEBI:17326 nucleoside triphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17326 CHEBI:17323 trans-pinosylvin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17323 CHEBI:91268 5-HPETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_91268 CHEBI:17321 5,6,7,8-tetrahydromethanopterin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17321 CHEBI:17322 chloric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17322 CHEBI:91264 11(R)-HEPE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_91264 CHEBI:17320 23,24-dihydrocucurbitacin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17320 CHEBI:91252 valienol 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91252 NCBITaxon:207598 Homininae organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_207598 Homo/Pan/Gorilla group UBERON:0010986 serratus ventralis pre-muscle mass biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010986 serratus anterior pre-muscle mass CHEBI:17318 N-(3,4-dichlorophenyl)malonamate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17318 CHEBI:17319 5'-deoxyadenosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17319 CHEBI:17316 2-N,6-O-disulfo-D-glucosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17316 CHEBI:17317 D-sorbose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17317 CHEBI:17314 13-hydroxydocosanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17314 CHEBI:17315 D-glucosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17315 CHEBI:17312 N(1)-acetylspermine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17312 CHEBI:17313 7,8-dihydroxycoumarin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17313 CHEBI:17310 pyridoxal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17310 CHEBI:17311 N(6),N(6),N(6)-trimethyl-L-lysine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17311 CHEBI:91253 GDP-valienol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91253 CHEBI:91254 phosphonoformate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91254 CHEBI:91255 CMP-5'-phosphonoformate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91255 CHEBI:32902 gibberellin A4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32902 UBERON:0034944 zone of organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034944 organ zonal region|organ zone|organ sector|organ region with floating fiat boundary UBERON:0034945 excreted gas biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034945 Any gaseous product of an excretory process. UBERON:0034946 gas excreted from digestive tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034946 intestinal gas|flatulence|flatus Any excreted gas that is produced by the digestive tract. UBERON:0034947 gas in respiratory system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034947 respiratory gas|respiratory system gas Any portion of gas located in a part of the respiratory system. UBERON:0034948 carbon dioxide in respiratory system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034948 respiratory CO2|respiratory system CO2 Any portion of gas located in a part of the respiratory system that is composed primarily of carbon dioxide. CHEBI:91286 5(S),15(S)-DiHETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_91286 CHEBI:91287 (5S)-hydroperoxy-18-hydroxy-EPE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_91287 CHEBI:91271 15-HPETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_91271 CHEBI:91272 13-HPODE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_91272 CHEBI:91273 pyrrolysine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_91273 CHEBI:91274 (7Z,10Z,13R,14E,16Z,19Z)-13-hydroxydocosapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_91274 UBERON:0034953 embryonic lymph sac biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034953 primary lymph sac A population of lymphatic endothelial cell precursors that will form the lymph vessels. UBERON:0034969 epithelial layer of duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034969 duct epithelium|ductal epithelium CHEBI:91293 14-oxo-DoHE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_91293 CHEBI:91294 12,18-dihydroxyoctadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91294 CHEBI:91295 ricinoleate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91295 CHEBI:91296 lysophosphatidylethanolamine 18:2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_91296 CHEBI:305790 thyroxine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_305790 CHEBI:91291 bacteriochlorophyllide g biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_91291 CHEBI:91292 alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-D-Gal-(1<->1')-N-acylsphingosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_91292 CHEBI:91297 lysophosphatidylcholine(0:0/16:0) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91297 CHEBI:91299 lysophosphatidylcholine(0:0/18:0) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91299 GO:0005978 glycogen biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0005978 MetaCyc:GLYCOGENSYNTH-PWY glycogen synthesis|glycogen formation|glycogen biosynthesis|glycogen anabolism The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues. GO:0030934 anchoring collagen complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030934 connecting collagen|linking collagen Any collagen complex which links one collagen assembly, such as a collagen fibril or sheet, to other structures. CHEBI:17271 3-phosphonatopyruvate(3-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17271 GO:0005979 regulation of glycogen biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0005979 regulation of glycogen anabolism|regulation of glycogen synthesis|regulation of glycogen formation|regulation of glycogen biosynthesis Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen. CHEBI:17272 propionate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17272 GO:0030935 sheet-forming collagen trimer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030935 hexagonal network-forming collagen A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers assemble into a sheet. GO:0005976 polysaccharide metabolic process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0005976 glycan metabolic process|polysaccharide metabolism|multicellular organismal polysaccharide metabolic process|glycan metabolism The chemical reactions and pathways involving a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. GO:0030932 amyloplast ADPG pyrophosphorylase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030932 An ADPG pyrophosphorylase complex found in the amyloplast. GO:0030933 chloroplast ADPG pyrophosphorylase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030933 An ADPG pyrophosphorylase complex found in the chloroplast. GO:0005977 glycogen metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0005977 glycogen metabolism The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages. CHEBI:17270 glycerol 2-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17270 GO:0005974 obsolete fibrinogen gamma chain biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005974 fibrinogen gamma chain OBSOLETE. (Was not defined before being made obsolete). GO:0030930 homotetrameric ADPG pyrophosphorylase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030930 A protein complex composed of four identical subunits that possesses ADPG pyrophosphorylase activity. Examples of this component are found in Bacterial species. GO:0005975 carbohydrate metabolic process biolink:BiologicalProcess go-plus goslim_drosophila|goslim_aspergillus|goslim_metagenomics|goslim_generic|goslim_pombe|goslim_chembl|goslim_yeast|goslim_agr|goslim_candida|goslim_pir|goslim_plant http://purl.obolibrary.org/obo/GO_0005975 Wikipedia:Carbohydrate_metabolism multicellular organismal carbohydrate metabolic process|single-organism carbohydrate metabolic process|carbohydrate metabolism The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule. GO:0030931 heterotetrameric ADPG pyrophosphorylase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030931 A protein complex composed of four different subunits that possesses ADPG pyrophosphorylase activity. An example of this process is found in Mus musculus. GO:0005972 obsolete fibrinogen alpha chain biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005972 fibrinogen alpha chain OBSOLETE. (Was not defined before being made obsolete). GO:0005973 obsolete fibrinogen beta chain biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005973 fibrinogen beta chain OBSOLETE. (Was not defined before being made obsolete). GO:0005970 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005970 GO:0005971 ribonucleoside-diphosphate reductase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005971 RNR complex|ribonucleotide reductase complex An enzyme complex composed of 2-4 or more subunits, which usually contains nonheme iron and requires ATP for catalysis. Catalyzes the formation of 2'-deoxyribonucleoside diphosphate from ribonucleoside diphosphate, using either thioredoxin disulfide or glutaredoxin disulfide as an acceptor. GO:0030938 collagen type XVIII trimer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030938 A collagen homotrimer of alpha1(XVIII) chains. GO:0030939 obsolete response to long-day photoperiod biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030939 response to long-day photoperiod OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a photoperiod, an intermittent cycle of light (day) and dark (night) photoperiod regimes, with the light phase being longer than the dark. GO:0030936 transmembrane collagen trimer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030936 MACIT Any collagen trimer that passes through a lipid bilayer membrane. GO:0030937 collagen type XVII trimer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030937 A collagen homotrimer of alpha1(XVII) chains; type XVII collagen triple helices span the plasma membrane and associate with hemidesmosomes and the basal lamina where they bind laminin. CHEBI:17268 myo-inositol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17268 CHEBI:17269 Latia luciferin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17269 CHEBI:17266 L-sorbose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17266 CHEBI:17264 phosphatidylglycerol phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17264 CHEBI:17265 O-(1->4)-alpha-L-dihydrostreptosylstreptidine 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17265 CHEBI:17262 dTDP-D-galacturonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17262 CHEBI:17263 estrone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17263 GO:0005989 lactose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0005989 lactose anabolism|lactose biosynthesis|lactose synthesis|lactose formation The chemical reactions and pathways resulting in the formation of lactose, the disaccharide galactopyranosyl-glucose. GO:0030923 metal incorporation into metallo-oxygen cluster biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030923 The formation of a cluster of several metal atoms, including manganese or calcium, with one or more bridging (mu-bond) oxygen atoms; amino acids residues in proteins that may ligate the metal oxygen cluster are histidine, aspartate, and glutamate. CHEBI:17260 butanoyl dihydrogen phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17260 GO:0030924 manganese incorporation into metallo-oxygen cluster biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030924 The incorporation of manganese into a metallo-oxygen cluster. CHEBI:17261 N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17261 GO:0030921 peptidyl-tyrosine dehydrogenation to form (Z)-2,3-didehydrotyrosine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030921 RESID:AA0183 The oxidation of the C alpha-C beta bond of peptidyl-tyrosine to form peptidyl-(Z)-2,3-didehydrotyrosine coupled with cyclization of neighboring residues. GO:0005987 sucrose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0005987 sucrose breakdown|sucrose catabolism|sucrose degradation The chemical reactions and pathways resulting in the breakdown of sucrose, the disaccharide fructofuranosyl-glucopyranoside. GO:0030922 peptidyl-tyrosine dehydrogenation to form (E)-2,3-didehydrotyrosine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030922 RESID:AA0365 The oxidation of the C alpha-C beta bond of peptidyl-tyrosine to form peptidyl-(E)-2,3-didehydrotyrosine coupled with cyclization of neighboring residues. GO:0005988 lactose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0005988 lactose metabolism The chemical reactions and pathways involving lactose, the disaccharide galactopyranosyl-glucose. GO:0005985 sucrose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0005985 sucrose metabolism The chemical reactions and pathways involving sucrose, the disaccharide fructofuranosyl-glucopyranoside. GO:0005986 sucrose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0005986 MetaCyc:SUCSYN-PWY sucrose anabolism|sucrose synthesis|sucrose formation|sucrose biosynthesis The chemical reactions and pathways resulting in the formation of sucrose, the disaccharide fructofuranosyl-glucopyranoside. GO:0030920 peptidyl-serine acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030920 The acetylation of peptidyl-serine. GO:0005983 starch catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0005983 MetaCyc:PWY-842 starch degradation|starch catabolism|starch breakdown The chemical reactions and pathways resulting in the breakdown of starch, the most important reserve polysaccharide in plants. GO:0005984 disaccharide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0005984 disaccharide metabolism The chemical reactions and pathways involving any disaccharide, sugars composed of two monosaccharide units. GO:0005981 regulation of glycogen catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0005981 regulation of glycogen catabolism|regulation of glycogen degradation|regulation of glycogen breakdown|regulation of glycogenolysis Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen. CHEBI:330772 dichloroarcyriaflavin A biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_330772 GO:0005982 starch metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0005982 starch metabolism The chemical reactions and pathways involving starch, the most important reserve polysaccharide in plants. It is a glucan consisting of two components, amylose and amylopectin, which are both glucose homopolymers. Starch is synthesized as a temporary storage form of carbon and can be catabolized to produce sucrose. GO:0030929 ADPG pyrophosphorylase complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0030929 Complex that possesses ADPG pyrophosphorylase activity. In all organisms where it has been found, the complex is a tetramer. In bacteria, it is a homotetramer. In plants, the complex is a heterotetramer composed small and large subunits. GO:0005980 glycogen catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0005980 MetaCyc:GLYCOCAT-PWY glycogen breakdown|glycogenolysis|glycogen catabolism|glycogen degradation The chemical reactions and pathways resulting in the breakdown of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues. CHEBI:42223 emodin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_42223 GO:0030927 manganese incorporation into metallo-oxygen cluster via bis-L-aspartato tris-L-glutamato L-histidino calcium tetramanganese tetroxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030927 RESID:AA0366 The incorporation of manganese into a 4Mn-Ca-4O complex by bis-L-aspartato tris-L-glutamato L-histidino calcium tetramanganese tetroxide as in the photosystem II catalytic site. GO:0015308 amiloride:proton antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015308 amiloride:hydrogen antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + amiloride(in) = H+(in) + amiloride(out). GO:0030928 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030928 GO:0015309 cycloheximide:proton antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015309 cycloheximide:hydrogen antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + cycloheximide(in) = H+(in) + cycloheximide(out). GO:0030925 calcium incorporation into metallo-oxygen cluster biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030925 The incorporation of calcium into a metallo-oxygen cluster. GO:0030926 calcium incorporation into metallo-oxygen cluster via bis-L-aspartato tris-L-glutamato L-histidino calcium tetramanganese tetroxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030926 RESID:AA0366 The incorporation of calcium into a 4Mn-Ca-4O complex by bis-L-aspartato tris-L-glutamato L-histidino calcium tetramanganese tetroxide as in the photosystem II catalytic site. GO:0015304 glucose uniporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015304 galactose, glucose uniporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) = glucose(in). GO:0015305 obsolete lactose, galactose:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015305 lactose, galactose:hydrogen symporter activity|lactose, galactose:proton symporter activity|lactose,galactose:proton symporter activity OBSOLETE. Catalysis of the reaction: (lactose or galactose)(out) + H+(out) = (lactose or galactose)(in) + H+(in). GO:0015306 sialate:cation symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015306 cation/sialate symporter activity|sialate transporter activity|cation:sialate symporter activity|sialate/cation symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sialate(out) + cation(out) = sialate(in) + cation(in). GO:0015307 obsolete drug:proton antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015307 carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity|drug:hydrogen antiporter activity OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + drug(in) = H+(in) + drug(out). GO:0015300 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015300 GO:0015301 anion:anion antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015301 Reactome:R-HSA-561041 anion exchanger activity|bicarbonate:chloride antiporter Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion A(out) + anion B(in) = anion A(in) + anion B(out). GO:0015302 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015302 CHEBI:17259 CDP-3,6-dideoxy-D-mannose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17259 GO:0015303 obsolete galactose, glucose uniporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015303 galactose, glucose uniporter activity OBSOLETE. Catalysis of the reaction: galactose or glucose(out) = galactose or glucose(in). CHEBI:17257 bis-gamma-glutamylcystine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17257 CHEBI:17258 7H-purine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17258 CHEBI:17255 N-carbamoyl-D-alpha-amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17255 CHEBI:17256 2'-deoxyadenosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17256 CHEBI:17253 1,2-benzoquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17253 CHEBI:17254 4-methylcatechol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17254 CHEBI:17251 pentalenene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17251 CHEBI:17252 17alpha-hydroxyprogesterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17252 GO:0005956 protein kinase CK2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005956 casein kinase II complex A protein complex that possesses protein serine/threonine kinase activity, and contains two catalytic alpha subunits and two regulatory beta subunits. Protein kinase CK2 complexes are found in nearly every subcellular compartment, and can phosphorylate many protein substrates in addition to casein. GO:0030912 response to deep water biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030912 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a deep water stimulus, being immersed in standing deep water throughout the life cycle. CHEBI:17293 2-aminophenoxazin-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17293 GO:0005957 obsolete debranching enzyme biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005957 debranching enzyme OBSOLETE. (Was not defined before being made obsolete). GO:0030913 paranodal junction assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030913 paranodal axoglial junction formation|paranodal junction biosynthesis|paranodal junction formation Formation of the junction between an axon and the glial cell that forms the myelin sheath. Paranodal junctions form at each paranode, i.e. at the ends of the unmyelinated nodes of Ranvier. CHEBI:17294 4,21-dehydrogeissoschizine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17294 GO:0005954 calcium- and calmodulin-dependent protein kinase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005954 CaMKII|CAMK2|calcium/calmodulin-dependent protein kinase complex An enzyme complex which in eukaryotes is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Catalyzes the phosphorylation of proteins to O-phosphoproteins. GO:0030910 olfactory placode formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030910 The formation of a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity. CHEBI:17291 L-fuconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17291 GO:0030911 TPR domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030911 tetratricopeptide repeat domain binding Interacting selectively and non-covalently with a tetratricopeptide repeat (TPR) domain of a protein, the consensus sequence of which is defined by a pattern of small and large hydrophobic amino acids and a structure composed of helices. GO:0005955 calcineurin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005955 protein phosphatase type 2B complex|calcium-dependent protein serine/threonine phosphatase complex A heterodimeric calcium ion and calmodulin dependent protein phosphatase composed of catalytic and regulatory subunits; the regulatory subunit is very similar in sequence to calmodulin. CHEBI:17292 beta-D-Gal-(1->3)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17292 GO:0005952 cAMP-dependent protein kinase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005952 3',5' cAMP-dependent protein kinase complex|PKA|cyclic AMP-dependent protein kinase complex|adenosine 3',5'-cyclophosphate-dependent protein kinase complex|3',5'-cAMP-dependent protein kinase complex An enzyme complex, composed of regulatory and catalytic subunits, that catalyzes protein phosphorylation. Inactive forms of the enzyme have two regulatory chains and two catalytic chains; activation by cAMP produces two active catalytic monomers and a regulatory dimer. GO:0005953 CAAX-protein geranylgeranyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005953 A heterodimeric enzyme, composed of an alpha and a beta subunit. Participates in the post-translational C-terminal modification of several small GTPases, allowing their targeting to the membrane. CHEBI:17290 (S)-3-hydroxybutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17290 GO:0005950 anthranilate synthase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005950 A heterotetrameric enzyme complex made up of two components I and two components II. Catalyzes the formation of anthranilate, pyruvate and L-glutamate from chorismate and L-glutamine. GO:0005951 carbamoyl-phosphate synthase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005951 carbamoyl phosphate synthase complex|arginine-specific carbamoyl phosphate synthetase complex|carbamoyl-phosphate synthase arginine-specific complex A protein complex that catalyzes the formation of carbamoyl phosphate; comprises a small subunit that binds and cleaves glutamine, and a large subunit that accepts the ammonia group cleaved from glutamine, binds all of the remaining substrates and effectors, and carries out all of the other catalytic events. CHEBI:32888 gamma-hexachlorocyclohexane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32888 GO:0030918 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030918 GO:0030919 peptidyl-serine O-acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030919 RESID:AA0364 The acetylation of peptidyl-serine to form peptidyl-O-acetyl-L-serine. GO:0030916 otic vesicle formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030916 otocyst formation|otocyst biosynthesis The process resulting in the transition of the otic placode into the otic vesicle, a transient embryonic structure formed during development of the vertebrate inner ear. GO:0030917 midbrain-hindbrain boundary development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030917 isthmic organizer development|isthmus development|MHB development|isthmomesencephalic boundary development|midbrain-hindbrain orgainizer development The process whose specific outcome is the progression of the midbrain-hindbrain boundary over time, from its formation to the mature structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. GO:0030914 STAGA complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030914 SPT3-TAF9-GCN5 acetylase complex|STAGA coactivator complex A large multiprotein complex that possesses histone acetyltransferase and is involved in regulation of transcription. The composition is similar to that of the SAGA complex; for example, the human complex contains the transcription-transformation cofactor TRRAP, hGCN5L acetylase, novel human ADA-like and SPT-like cofactors, and a subset of TAFs. GO:0030915 Smc5-Smc6 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030915 A conserved complex that contains a heterodimer of SMC proteins (Smc5p and Smc6p, or homologs thereof) and several other proteins, and is involved in DNA repair and maintaining cell cycle arrest following DNA damage. In S. cerevisiae, this is an octameric complex called Mms21-Smc5-Smc6 complex, with at least five of its subunits conserved in fission yeast and humans. CHEBI:17289 homoserine lactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17289 CHEBI:17286 deacetylisoipecoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17286 CHEBI:17287 N-phosphocreatine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17287 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005958 A large protein complex which is involved in the repair of DNA double-strand breaks and, in mammals, V(D)J recombination events. It consists of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs), the DNA end-binding heterodimer Ku, the nuclear phosphoprotein XRCC4 or a homolog thereof, and DNA ligase IV. CHEBI:17284 5-phospho-D-ribosylamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17284 GO:0005959 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005959 CHEBI:17285 L-cysteic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17285 GO:0030901 midbrain development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030901 mesencephalon development The process whose specific outcome is the progression of the midbrain over time, from its formation to the mature structure. The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles). GO:0005967 mitochondrial pyruvate dehydrogenase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005967 pyruvate dehydrogenase complex (lipoamide) Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA in eukaryotes; includes subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). The This Eukaryotic form usually contains more subunits than its bacterial counterpart; for example, one known complex contains 30 E1 dimers, 60 E2 monomers, and 6 E3 dimers as well as a few copies of pyruvate dehydrogenase kinase and pyruvate dehydrogenase phosphatase. CHEBI:17282 3-(indol-3-yl)lactate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17282 CHEBI:17283 1-phosphatidyl-1D-myo-inositol 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17283 GO:0030902 hindbrain development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030902 rhombencephalon development The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium). GO:0005968 Rab-protein geranylgeranyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005968 Rab geranylgeranyltransferase complex|RabGGTase complex|RAB-protein geranylgeranyltransferase complex|GGTase-II complex An protein-containing complex which catalyzes of the transfer of a geranyl-geranyl group from geranylgeranyl pyrophosphate to a Rab protein. In mammals it is composed of an alpha and a beta subunit, and associates with an accessory protein Rep (Rab escort protein). GO:0005965 protein farnesyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005965 A protein complex that possesses protein farnesyltransferase activity. GO:0005966 cyclic-nucleotide phosphodiesterase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005966 photoreceptor cyclic-nucleotide phosphodiesterase complex An enzyme complex that catalyzes the hydrolysis of bonds in a cyclic nucleotide. CHEBI:17281 2-deoxy-D-ribono-1,4-lactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17281 GO:0030900 forebrain development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030900 prosencephalon development The process whose specific outcome is the progression of the forebrain over time, from its formation to the mature structure. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions). GO:0005963 magnesium-dependent protein serine/threonine phosphatase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005963 An enzyme complex that catalyzes the removal of serine- or threonine-bound phosphate groups from a wide range of phosphoproteins, including a number of enzymes that have been phosphorylated under the action of a kinase. GO:0005964 phosphorylase kinase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005964 An enzyme complex that catalyzes the phosphorylation of phosphorylase b to form phosphorylase a. GO:0005961 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005961 GO:0005962 mitochondrial isocitrate dehydrogenase complex (NAD+) biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005962 Mitochondrial complex that possesses isocitrate dehydrogenase (NAD+) activity. GO:0030909 non-intein-mediated protein splicing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030909 The post-translational removal of peptide sequences from within a protein sequence, by a process not involving inteins. CHEBI:32898 baccatin III biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32898 CHEBI:42202 daidzein 7-O-beta-D-glucoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_42202 GO:0005960 glycine cleavage complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0005960 Wikipedia:Glycine_decarboxylase_complex glycine cleavage system|glycine decarboxylase complex|glycine dehydrogenase (decarboxylating) complex|glycine dehydrogenase complex (decarboxylating)|glycine synthase complex A protein complex that catalyzes the reversible oxidation of glycine. In E. coli, it has four components: dihydrolipoamide dehydrogenase, glycine dehydrogenase (decarboxylating), lipoyl-GcvH-protein and aminomethyltransferase, also known as L, P, H, and T. GO:0030907 MBF transcription complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030907 MBF|Mlu1-box binding factor|DSC1 transcription factor complex A protein complex that binds to the Mlu1 cell cycle box (MCB) promoter element, consensus sequence ACGCGN, and is involved in regulation of transcription during the G1/S transition of the cell cycle. In Saccharomyces, the complex contains a heterodimer of the DNA binding protein Mbp1p and the activator Swi6p, and is associated with additional proteins known as Nrm1p, Msa1p, and Msa2p; in Schizosaccharomyces the complex contains Res1p, Res2p, and Cdc10p. GO:0030908 protein splicing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030908 Wikipedia:Protein_splicing The post-translational removal of peptide sequences from within a protein sequence. GO:0030905 retromer, tubulation complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030905 SNX-BAR dimer|heterodimeric membrane-deforming retromer subcomplex|retromer complex, outer shell The dimeric subcomplex of the retromer, believed to be peripherally associated with the membrane. This dimeric complex is responsible for remodelling endosomal membranes to form a tube-structure to which cargo molecules are selected for recycling. The budding yeast complex comprises Vps5p and Vps17p, and may contain multiple copies of a Vps5p/Vps17p dimer. The mammalian complex contains SNX1 or SNX2 dimerized with SNX5 or SNX6. GO:0030906 retromer, cargo-selective complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030906 retromer complex, inner shell|retromer, cargo recognition complex|cargo-selective retromer subcomplex|retromer CSC|retromer, CRC The trimeric subcomplex of the retromer, believed to be closely associated with the membrane. This trimeric complex is responsible for recognizing and binding to cargo molecules. The complex comprises three Vps proteins in both yeast and mammalian cells: Vps35p, Vps29p, and Vps26p in yeast, and VPS35, VPS29 and VPS26A or VPS26B in mammals. GO:0030903 notochord development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030903 The process whose specific outcome is the progression of the notochord over time, from its formation to the mature structure. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column. GO:0030904 retromer complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0030904 A conserved hetero-pentameric membrane-associated complex involved in retrograde transport from endosomes to the Golgi apparatus. The budding yeast retromer comprises Vps35p, Vps29p, Vps26p, Vps5p, and Vps17p. The mammalian complex shows slight variation in composition compared to yeast, and comprises SNX1 or SNX2, SNX5 or SNX6, VPS26A or VPS26B, VPS29, and VPS35. CHEBI:32892 nonane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32892 CHEBI:32896 (2R)-O-phospho-3-sulfolactic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32896 CHEBI:32897 10-deacetyl-2-debenzoylbaccatin III biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32897 CHEBI:17279 N-succinyl-LL-2,6-diaminopimelic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17279 CHEBI:17277 UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17277 CHEBI:17278 5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17278 CHEBI:17275 2-isopropylmaleic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17275 CHEBI:17276 phloretin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17276 GO:0005969 serine-pyruvate aminotransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005969 serine-pyruvate aminotransferase, type 1 complex|serine-pyruvate aminotransferase, type 2B complex An enzyme complex that catalyzes the formation of hydroxypyruvate and alanine from serine and pyruvate. CHEBI:17274 aldehydo-N-acyl-D-glucosamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17274 GO:0005934 cellular bud tip biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005934 The end of a cellular bud distal to the site of attachment to the mother cell. GO:0005935 cellular bud neck biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005935 The constriction between the mother cell and daughter cell (bud) in an organism that reproduces by budding. GO:0005932 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005932 GO:0005933 cellular bud biolink:CellularComponent go-plus goslim_pir|goslim_candida|goslim_yeast http://purl.obolibrary.org/obo/GO_0005933 A protuberance from a cell of an organism that reproduces by budding, which will grow larger and become a separate daughter cell after nuclear division, cytokinesis, and cell wall formation (when appropriate). The daughter cell may completely separate from the mother cell, or the mother and daughter cells may remain associated. GO:0005930 axoneme biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0005930 Wikipedia:Axoneme cilium axoneme|flagellum axoneme|flagellar axoneme|ciliary axoneme The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements. GO:0005931 axonemal nexin link biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005931 nexin complex|axonemal interdoublet link A protein complex found in the axoneme of eukaryotic cilia and flagella. It forms interconnections between the microtubule outer doublets that surround the inner central pair of microtubules. CHEBI:32867 D-prolinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32867 CHEBI:81874 nogalaviketone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_81874 CHEBI:32868 D-prolinium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32868 CHEBI:81873 12-deoxynogalonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_81873 CHEBI:32860 valinium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32860 CHEBI:17228 taurocyamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17228 CHEBI:17229 5-(3-hydroxy-4-acetoxybut-1-ynyl)-2,2'-bithiophene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17229 CHEBI:32862 L-prolinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32862 CHEBI:17226 rosmarinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17226 CHEBI:32863 secondary amine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32863 CHEBI:32864 L-prolinium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32864 CHEBI:91209 glycosmisic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_91209 CHEBI:17224 4-methylumbelliferone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17224 CHEBI:17225 salutaridine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17225 CHEBI:17223 polyprenyl glucosyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17223 GO:0005938 cell cortex biolink:CellularComponent go-plus goslim_yeast|goslim_candida|goslim_aspergillus http://purl.obolibrary.org/obo/GO_0005938 Wikipedia:Cell_cortex cell periphery|peripheral cytoplasm The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins. CHEBI:17221 beta-myrcene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17221 GO:0005936 obsolete shmoo biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005936 shmoo OBSOLETE. The characteristic projection formed in response to mating pheromone by cells of Saccharomyces and other fungi with similar life cycles. Named after the Al Capp cartoon character, whose shape it resembles. GO:0005937 mating projection biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0005937 conjugation tube|shmoo The projection formed by unicellular fungi in response to mating pheromone. GO:0005945 6-phosphofructokinase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005945 A protein complex that possesses 6-phosphofructokinase activity; homodimeric, homooctameric, and allosteric homotetrameric forms are known. GO:0005946 alpha,alpha-trehalose-phosphate synthase complex (UDP-forming) biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005946 trehalose-6-phosphate synthase complex|UDP-glucose-glucosephosphate glucosyltransferase complex|trehalose-6-phosphate synthase/phosphatase A protein complex that possesses alpha,alpha-trehalose-phosphate synthase (UDP-forming) and trehalose-phosphatase activities, and thus catalyzes two reactions in trehalose biosynthesis. In the complex identified in Saccharomyces, Tps1p has alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity, Tps2p has trehalose 6-phosphate phosphatase activity; Tps3p is a regulatory subunit, and an additional subunit, Tsl1p, may be present. GO:0005943 phosphatidylinositol 3-kinase complex, class IA biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005943 1-phosphatidylinositol-4-phosphate kinase, class IA complex|1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex|phosphoinositide 3-kinase complex, class IA|class IA PI3K complex A class I phosphatidylinositol 3-kinase complex that possesses 1-phosphatidylinositol-4-phosphate 3-kinase activity; comprises a catalytic class IA phosphoinositide 3-kinase (PI3K) subunit and an associated SH2 domain-containing regulatory subunit that is a member of a family of related proteins often called p85 proteins. Through the interaction with the SH2-containing adaptor subunits, Class IA PI3K catalytic subunits are linked to tyrosine kinase signaling pathways. GO:0005944 phosphatidylinositol 3-kinase complex, class IB biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005944 1-phosphatidylinositol-4-phosphate kinase, class IB complex|1-phosphatidylinositol-4-phosphate 3-kinase, class IB complex|phosphoinositide 3-kinase complex, class IB|class IB PI3K complex A class I phosphatidylinositol 3-kinase complex that possesses 1-phosphatidylinositol-4-phosphate 3-kinase activity; comprises a catalytic class IB phosphoinositide 3-kinase (PI3K) subunit and an associated regulatory subunit that is larger than, and unrelated to, the p85 proteins present in class IA complexes. Class IB PI3Ks are stimulated by G-proteins and do not interact with the SH2-domain containing adaptors that bind to Class IA PI3Ks. GO:0005941 obsolete unlocalized protein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005941 unlocalized protein complex OBSOLETE. Used as a holding place for cellular components whose precise localization is, as yet, unknown, or has not been determined by GO (the latter is the major reason for nodes to have this parent); this term should not be used for annotation of gene products. GO:0005942 phosphatidylinositol 3-kinase complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0005942 PIK3CA-PIK3R1 complex|phosphoinositide 3-kinase complex|1-phosphatidylinositol 3-kinase complex|PI3-kinase p85-subunit alpha- PI3-kinase p110 complex|PIK3C3-PIK3R4 complex|PI3K complex A protein complex capable of phosphatidylinositol 3-kinase activity and containing subunits of any phosphatidylinositol 3-kinase (PI3K) enzyme. These complexes are divided in three classes (called I, II and III) that differ for their presence across taxonomic groups and for the type of their constituents. Catalytic subunits of phosphatidylinositol 3-kinase enzymes are present in all 3 classes; regulatory subunits of phosphatidylinositol 3-kinase enzymes are present in classes I and III; adaptor proteins have been observed in class II complexes and may be present in other classes too. GO:0005940 septin ring biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005940 Wikipedia:Septin_ring A tight ring-shaped structure that forms in the division plane at the site of cytokinesis; composed of members of the conserved family of filament-forming proteins called septins as well as septin-associated proteins. This type of septin structure is observed at the bud neck of budding fungal cells, at the site of cell division in animal cells, at the junction between the mother cell and a pseudohyphal projection, and also within hyphae of filamentous fungi at sites where a septum will form. CHEBI:32876 tertiary amine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32876 CHEBI:32877 primary amine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32877 CHEBI:32878 alkene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32878 CHEBI:32879 propane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32879 CHEBI:17219 limonene-1,2-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17219 CHEBI:32871 prolinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32871 CHEBI:32872 prolinium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32872 CHEBI:17217 2-butenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17217 CHEBI:17215 methyl L-tyrosinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17215 CHEBI:32874 proline residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32874 CHEBI:32875 methyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32875 CHEBI:17216 oxidized Cypridina luciferin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17216 CHEBI:17213 D-lysopine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17213 CHEBI:17214 (2S)-2-isopropyl-3-oxosuccinate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17214 CHEBI:17211 geranyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17211 CHEBI:17212 1,2-dihydroxydibenzothiophene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17212 GO:0005949 obsolete aminoadipate-semialdehyde dehydrogenase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005949 aminoadipate-semialdehyde dehydrogenase complex OBSOLETE. A heterodimeric enzyme composed of an alpha and beta subunit. Catalyzes the formation of L-2-aminoadipate from L-2-aminoadipate 6-semialdehyde. CHEBI:17210 (S)-4-hydroxymandelate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17210 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005947 2-oxoglutarate dehydrogenase complex Mitochondrial complex that possesses alpha-ketoglutarate dehydrogenase activity. GO:0005948 acetolactate synthase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005948 acetohydroxyacid synthase complex A dimeric (a large and a small chain) or tetrameric (two large and two small chains) enzyme complex. Catalyzes the formation of acetolactate from pyruvate. GO:0005912 adherens junction biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005912 Wikipedia:Adherens_junction cell-cell adherens junction A cell-cell junction composed of the epithelial cadherin-catenin complex. The epithelial cadherins, or E-cadherins, of each interacting cell extend through the plasma membrane into the extracellular space and bind to each other. The E-cadherins bind to catenins on the cytoplasmic side of the membrane, where the E-cadherin-catenin complex binds to cytoskeletal components and regulatory and signaling molecules. GO:0005913 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005913 CHEBI:17250 2-hydroxy-4-oxobutane-1,2,4-tricarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17250 GO:0005911 cell-cell junction biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005911 NIF_Subcellular:sao1922892319 intercellular junction A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic intercellular bridges, such as ring canals in insects. CHEBI:32844 N-acetyl-4-O-acetylneuraminic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32844 CHEBI:32845 serinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32845 CHEBI:32846 serinium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32846 CHEBI:32848 serine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_32848 CHEBI:91228 2,2-dihydroxyspirilloxanthin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91228 CHEBI:295975 choline phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_295975 CHEBI:32840 D-serinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32840 CHEBI:91229 2'-hydroxy-2-oxospirilloxanthin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91229 CHEBI:32841 D-serinium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32841 CHEBI:17248 6-lactoyl-5,6,7,8-tetrahydropterin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17248 CHEBI:17249 D-nopaline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17249 CHEBI:17246 poly(vinyl alcohol) macromolecule biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17246 CHEBI:17247 N-isopropylammelide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17247 GO:0005918 septate junction biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005918 NIF_Subcellular:sao427941916 septate desmosome A cell-cell junction that forms a continuous band around each cell in an epithelium; within the septate junction the membranes of adjacent cells maintain a constant distance of approximately 15 nm; found in arthropods. CHEBI:17244 5,6-dihydroquinoline-2,5,6-triol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17244 CHEBI:17245 carbon monoxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17245 GO:0005919 pleated septate junction biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005919 pleated desmosome A septate junction in which regular arrays of electron-dense septae span the intermembrane space. CHEBI:91227 2-hydroxyspirilloxanthin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91227 GO:0005916 fascia adherens biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005916 Wikipedia:Fascia_adherens A cell-cell junction that contains the transmembrane protein N-cadherin, which interacts with identical molecules from neighbouring cells to form a tight mechanical intercellular link; forms a large portion of the intercalated disc, the structure at which myofibrils terminate in cardiomyocytes. CHEBI:17242 dehydroascorbic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17242 GO:0005917 nephrocyte diaphragm biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005917 nephrocyte junction A specialized cell-cell junction found between nephrocytes of the insect kidney, which is adapted for filtration of hemolymph. The insect nephrocyte is anatomically and functionally similar to the glomerular podocyte of vertebrates. CHEBI:17243 mono(2-ethylhexyl) phthalate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17243 CHEBI:91221 2-hydroxyspheroidene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91221 GO:0005914 spot adherens junction biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005914 punctum adherens|dense plaque A small cell-cell adherens junction assembled during the cellularization stage of insect embyrogenesis; spot adherens junctions later fuse to form the zonula adherens. CHEBI:17240 itaconate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17240 CHEBI:91223 2,2-dihydroxyspheroidene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_91223 GO:0005915 zonula adherens biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005915 NIF_Subcellular:sao1400623473 intermediate junction|adhesion belt|belt desmosome|zonula adhaerens A cell-cell adherens junction which forms a continuous belt near the apex of epithelial cells. CHEBI:17241 1H-pyrazole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17241 GO:0005923 bicellular tight junction biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005923 Wikipedia:Tight_junction|NIF_Subcellular:sao1939999134 zonula occludens An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes. GO:0005924 obsolete cell-substrate adherens junction biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005924 hemi-adherens junction OBSOLETE. An adherens junction which connects a cell to the extracellular matrix. GO:0005921 gap junction biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005921 NIF_Subcellular:sao118541872|Wikipedia:Gap_junction zonula communicans|intercellular gap junction channel|gap junction plaque|communicating junction|gap junction macula|macula communicans|electrotonic synapse|electrical synapse A cell-cell junction composed of pannexins or innexins and connexins, two different families of channel-forming proteins. GO:0005922 connexin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005922 NIF_Subcellular:sao445019788 connexon complex|connexon An assembly of six molecules of connexin, made in the Golgi apparatus and subsequently transported to the plasma membrane, where docking of two connexons on apposed plasma membranes across the extracellular space forms a gap junction. GO:0005920 smooth septate junction biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005920 zonula continua A septate junction that lacks the regular arrays of electron-dense septae found in pleated septate junctions. CHEBI:32855 D-valinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32855 CHEBI:32856 D-valinium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32856 CHEBI:32857 D-valyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32857 CHEBI:32859 valinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32859 CHEBI:17239 CDP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17239 CHEBI:32851 L-valinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32851 CHEBI:17237 (E)-4-(trimethylammonio)but-2-enoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17237 CHEBI:32852 L-valinium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32852 CHEBI:32853 L-valyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_32853 CHEBI:17236 2-hydroxy-6-oxohexa-2,4-dienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17236 GO:0005929 cilium biolink:CellularComponent go-plus goslim_generic|goslim_chembl|goslim_pir|goslim_drosophila http://purl.obolibrary.org/obo/GO_0005929 Wikipedia:Cilium|NIF_Subcellular:sao787716553|FMA:67181 primary cilium|eukaryotic flagellum|flagellum|microtubule-based flagellum A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body. CHEBI:17233 (3Z,5S)-3-(1-hydroxyethylidene)-5-{[4-(3-methylbut-2-en-1-yl)-1H-indol-3-yl]methyl}pyrrolidine-2,4-dione biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17233 CHEBI:17234 glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17234 CHEBI:17231 m-cresol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17231 GO:0005927 muscle tendon junction biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005927 myotendinous junction A cell-substrate junction found at the terminal anchorage site of skeletal muscle cells to tendons. GO:0005928 obsolete apical hemi-adherens junction biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005928 apical cell-substrate adherens junction|apical dense plaque OBSOLETE. A cell-substrate adherens junction found in the apical region of a cell, such as those found in cuticle-secreting epithelia, which connect the apical membrane to the cuticle. CHEBI:17232 L-glutamic 5-semialdehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17232 GO:0005925 focal adhesion biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005925 Wikipedia:Focal_adhesion HAJ|connecting hemi-adherens junction|hemi-adherens junction|focal contact|adhesion plaque A cell-substrate junction that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments. In insects focal adhesion has also been referred to as hemi-adherens junction (HAJ). CHEBI:17230 homocysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17230 GO:0005926 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005926 CHEBI:134027 1,2-bis(octadec-9-enoyl)phosphatidic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134027 GO:0015377 cation:chloride symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015377 cation:chloride cotransporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cation(out) + Cl-(out) = cation(in) + Cl-(in). GO:0015378 sodium:chloride symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015378 Reactome:R-HSA-426130|Reactome:R-HSA-5623705 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + Cl-(out) = Na+(in) + Cl-(in). GO:0015379 potassium:chloride symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015379 Reactome:R-HSA-5623806|Reactome:R-HSA-426155 potassium ion symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + Cl-(out) = K+(in) + Cl-(in). GO:0015373 anion:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015373 monovalent anion:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monovalent anion(out) + Na+(out) = monovalent anion(in) + Na+(in). GO:0015374 neutral, basic amino acid:sodium:chloride symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015374 neutral, cationic amino acid:sodium:chloride symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neutral/basic amino acid(out) + Na+(out) + Cl-(out) = neutral/basic amino acid(in) + Na+(in) + Cl-(in). GO:0015375 glycine:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015375 Reactome:R-HSA-444120|Reactome:R-HSA-5660840 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine(out) + Na+(out) = glycine(in) + Na+(in). GO:0015376 obsolete betaine/GABA:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015376 betaine/GABA:sodium symporter activity OBSOLETE. Catalysis of the reaction: (betaine or gamma-aminobutyric acid)(out) + Na+(out) = (betaine or gamma-aminobutyric acid)(in) + Na+(in). CHEBI:134022 N-arachidonoyl-L-phenylalaninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134022 GO:0015370 solute:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015370 Reactome:R-HSA-8876283 proline/glycine/betaine:hydrogen/sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + Na+(out) = solute(in) + Na+(in). GO:0015371 galactose:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015371 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose(out) + Na+(out) = glucose(in) + Na+(in). CHEBI:134020 N-oleoyl-L-phenylalaninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134020 GO:0015372 obsolete glutamate/aspartate:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015372 glutamate/aspartate:sodium symporter activity OBSOLETE. Catalysis of the reaction: (glutamate or aspartate)(out) + Na+(out) = (glutamate or aspartate)(in) + Na+(in). CHEBI:134021 N-oleoyl-L-phenylalanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134021 GO:0015390 purine-specific nucleoside:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015390 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: purine(out) + Na+(out) = nucleoside(in) + Na+(in). OBA:VT0010248 hemolymphoid system trait biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_VT0010248 The quality when measured in hemolymphoid system. CHEBI:134035 N-oleoyl-L-leucinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134035 GO:0015388 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015388 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015389 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: (pyrimidine nucleoside or adenine)(out) + Na+(out) = (pyrimidine nucleoside or adenine)(in) + Na+(in). GO:0015384 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015384 GO:0015385 sodium:proton antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015385 Reactome:R-HSA-5661039|Reactome:R-HSA-5661086|Reactome:R-HSA-426015|Reactome:R-HSA-425965|Reactome:R-HSA-2872463|Reactome:R-HSA-425994|RHEA:29251|Reactome:R-HSA-425983|Reactome:R-HSA-2872444 pH-dependent sodium:proton antiporter activity|sodium/hydrogen antiporter activity|sodium:hydrogen exchanger|pH-dependent sodium:hydrogen antiporter activity|sodium:hydrogen exchange activity|sodium:hydrogen antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + H+(in) = Na+(in) + H+(out). GO:0015386 potassium:proton antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015386 RHEA:29467 potassium:hydrogen antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(in) + H+(out) = K+(out) + H+(in). GO:0015387 potassium:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015387 RHEA:28490 potassium:hydrogen symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + H+(out) = K+(in) + H+(in). CHEBI:134033 N-oleoyl-L-glutaminate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134033 GO:0015380 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015380 GO:0015381 high-affinity sulfate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015381 high affinity sulfate permease activity|high affinity sulfate transmembrane transporter activity|high affinity sulphate permease activity Enables the secondary active high affinity transfer of sulfate from one side of a membrane to the other. Secondary active transport is the transfer of a solute across a membrane, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. In high-affinity transport the transporter is able to bind thesolute even if it is only present at very low concentrations. GO:0015382 sodium:sulfate symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015382 Reactome:R-HSA-433099|Reactome:R-HSA-433114 sodium:sulphate symporter activity|sodium:sulfate cotransporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + Na+(out) = sulfate(in) + Na+(in). CHEBI:134031 N-oleoyl-L-serinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134031 GO:0015383 sulfate:bicarbonate antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015383 sulphate:bicarbonate antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + bicarbonate(in) = sulfate(in) + bicarbonate(out). GO:0030998 linear element biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030998 A proteinaceous scaffold associated with fission yeast chromosomes during meiotic prophase. Linear elements consist of a protein complex, LinE, with four main structural components (Rec10, Rec25, Rec27, and Mug20 in S. pombe) associated with chromatin. The resulting structure is related to but not equivalent to the synaptonemal complex. GO:0030999 linear element assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030999 linear element formation The cell cycle process in which linear elements are assembled in association with fission yeast chromosomes during meiotic prophase. Linear element assembly begins with LinE complex formation and ends when LinE complexes are associated with chromatin in structures visible as nuclear foci. A linear element is a proteinaceous scaffold related to the synaptonemal complex. GO:0030996 obsolete mitotic cell cycle arrest in response to nitrogen starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030996 cell cycle arrest in response to nitrogen starvation OBSOLETE. The process in which the mitotic cell cycle is halted during one of the normal phases (G1, S, G2, M) as a result of deprivation of nitrogen. GO:0030997 regulation of centriole-centriole cohesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030997 Any process that modulates the extent to which the two centrioles within a centrosome remain tightly paired; may be mediated by the assembly and disassembly of a proteinaceous linker. GO:0030994 primary cell septum disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030994 hydrolysis of primary cell septum|primary cell septum hydrolysis|primary septum hydrolysis Dissolution of the primary septum during cell separation. GO:0030995 cell septum edging catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030995 hydrolysis of edging of cell septum|hydrolysis of cell septum edging|cell septum edging hydrolysis|septum edging hydrolysis The chemical reactions and pathways resulting in the dissolution of the septum edging during cell separation. GO:0015359 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015359 CHEBI:134004 alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134004 CHEBI:134005 alpha-D-Glc-(1->2)-alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134005 CHEBI:134002 alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134002 CHEBI:134003 alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134003 GO:0015355 secondary active monocarboxylate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015355 monocarboxylate porter activity Catalysis of the movement of a monocarboxylate, any compound containing a single carboxyl group (COOH or COO-), by uniport, symport or antiport across a membrane by a carrier-mediated mechanism. GO:0015356 obsolete monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015356 monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity OBSOLETE. (Was not defined before being made obsolete). GO:0015357 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015357 GO:0015358 obsolete amino acid/choline transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015358 amino acid/choline transmembrane transporter activity OBSOLETE. (Was not defined before being made obsolete). GO:0030992 intraciliary transport particle B biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030992 IFT complex B|IFT B complex|intraflagellar transport particle B|intraflagellar transport complex B The larger subcomplex of the intraciliary transport particle; characterized complexes have molecular weights around 550 kDa. GO:0015351 bilirubin secondary active transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015351 bilitranslocase|bilirubin porter activity Enables the transfer of bilirubin from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. GO:0015352 obsolete secondary active sterol transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015352 sterol porter activity OBSOLETE. Enables the transfer of sterol from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction. GO:0030993 axonemal heterotrimeric kinesin-II complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030993 A kinesin complex found in eukaryotic axonemes that contains two distinct plus end-directed kinesin motor proteins and at least one accessory subunit, and that functions in the anterograde transport of molecules (cargo) from the basal body to the distal tip of the axoneme. GO:0030990 intraciliary transport particle biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0030990 IFT complex|intraflagellar transport particle|intraflagellar transport complex A nonmembrane-bound oligomeric protein complex that participates in bidirectional transport of molecules (cargo) along axonemal microtubules. GO:0015353 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015353 GO:0030991 intraciliary transport particle A biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030991 IFT A complex|IFT complex A|intraflagellar transport particle A|intraflagellar transport complex A The smaller subcomplex of the intraciliary transport particle; characterized complexes have molecular weights of 710-760 kDa. GO:0015354 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015354 CHEBI:134000 alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134000 CHEBI:134001 norbelladine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134001 GO:0015350 methotrexate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015350 methotrexate transporter activity Enables the transfer of methotrexate, 4-amino-10-methylformic acid from one side of a membrane to the other. Methotrexate is a folic acid analogue and a potent competitive inhibitor of dihydrofolate reductase. GO:0030989 dynein-driven meiotic oscillatory nuclear movement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030989 horsetail nuclear movement|HNM|horsetail movement Oscillatory movement of the nucleus involved in meiosis I. This oscillatory movement is led by an astral microtubule array emanating from the spindle pole body, and driven by the microtubule motor cytoplasmic dynein. GO:0030987 high molecular weight kininogen receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030987 Interacting selectively and non-covalently with a high molecular weight kininogen receptor. GO:0030988 high molecular weight kininogen receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030988 A protein complex that acts as a receptor for high molecular weight kininogens. In humans, this receptor includes the CK1 and uPAR proteins. GO:0030985 high molecular weight kininogen binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030985 HMW kininogen binding|HK binding Interacting selectively and non-covalently with a kininogen of high molecular mass. GO:0030986 low molecular weight kininogen binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030986 LMW kininogen binding|LK binding Interacting selectively and non-covalently with a kininogen of low molecular mass. GO:0030983 mismatched DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030983 mispair binding|mispaired DNA binding Interacting selectively and non-covalently with double-stranded DNA containing one or more mismatches. GO:0030984 kininogen binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030984 Interacting selectively and non-covalently with a kininogen, any of a group of plasma proteins that are kinin precursors. GO:0015366 malate:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015366 malate:hydrogen symporter activity|L-malic acid:proton symporter activity|malate permease|L-malic acid permease Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: malate(out) + H+(out) = malate(in) + H+(in). CHEBI:134019 hydroperoxy polyunsaturated fatty acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134019 GO:0015367 oxoglutarate:malate antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015367 Reactome:R-HSA-376851|Reactome:R-HSA-198440 2-oxoglutarate/malate carrier protein Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: oxoglutarate(out) + malate(in) = oxoglutarate(in) + malate(out). GO:0015368 calcium:cation antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015368 Reactome:R-HSA-425822 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + cation(out) = Ca2+(out) + cation(in). CHEBI:134017 11a-hydroxytetracycline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134017 CHEBI:134018 N-acyl-gamma-aminobutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134018 GO:0015369 calcium:proton antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015369 Reactome:R-HSA-8949687|RHEA:29671 calcium:hydrogen antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + H+(out) = Ca2+(out) + H+(in). GO:0015362 high-affinity sodium:dicarboxylate symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015362 Reactome:R-HSA-433101 high affinity sodium:dicarboxylate cotransporter activity|high affinity sodium:dicarboxylate symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. GO:0030981 cortical microtubule cytoskeleton biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030981 The portion of the microtubule cytoskeleton that lies just beneath the plasma membrane. GO:0030982 adventurous gliding motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030982 adventurous gliding movement A process involved in the controlled movement of a bacterial cell powered by the rearward secretion of carbohydrate slime. GO:0015363 obsolete dicarboxylate (succinate/fumarate/malate) antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015363 dicarboxylate (succinate/fumarate/malate) antiporter activity OBSOLETE. (Was not defined before being made obsolete). GO:0015364 dicarboxylate:inorganic phosphate antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015364 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + inorganic phosphate(in) = dicarboxylate(in) + inorganic phosphate(out). GO:0030980 alpha-glucan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030980 alpha-glucan degradation|alpha-glucan breakdown|alpha-glucan catabolism The chemical reactions and pathways resulting in the breakdown of alpha-glucans. GO:0015365 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015365 GO:0015360 acetate:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015360 hydrogen:acetate symporter activity|acetate:hydrogen symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: acetate(out) + H+(out) = acetate(in) + H+(in). GO:0015361 low-affinity sodium:dicarboxylate symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015361 Reactome:R-HSA-433131 low affinity sodium:dicarboxylate cotransporter activity|low affinity sodium:dicarboxylate symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations. GO:0030978 alpha-glucan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030978 alpha-glucan metabolism The chemical reactions and pathways involving alpha-glucans, compounds composed of glucose residues linked by alpha-D-glucosidic bonds. GO:0030979 alpha-glucan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030979 alpha-glucan anabolism|alpha-glucan synthesis|alpha-glucan formation|alpha-glucan biosynthesis The chemical reactions and pathways resulting in the formation of alpha-glucans, compounds composed of glucose residues linked by alpha-D-glucosidic bonds. GO:0030976 thiamine pyrophosphate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030976 aneurine pyrophosphate binding|thiamin pyrophosphate binding|cocarboxylase binding|TPP binding|diphosphothiamin binding Interacting selectively and non-covalently with thiamine pyrophosphate, the diphosphoric ester of thiamine. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases. GO:0030977 taurine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030977 Interacting selectively and non-covalently with taurine. GO:0030974 thiamine pyrophosphate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030974 thiamin diphosphate transport|thiamin pyrophosphate transport|thiamine pyrophosphate transport|thiamine diphosphate transport|TPP transport The process in which thiamine pyrophosphate is transported across a membrane. GO:0030975 thiamine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030975 vitamin B1 binding|thiamin binding Interacting selectively and non-covalently with thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver. GO:0030972 obsolete cleavage of cytosolic proteins involved in execution phase of apoptosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030972 cleavage of cytosolic proteins involved in apoptosis|apoptotic cleavage of cytosolic proteins|cleavage of cytosolic proteins involved in execution phase of apoptosis OBSOLETE. The proteolytic degradation of proteins in the cytosol that contributes to apoptosis. GO:0030973 molybdate ion binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030973 Interacting selectively and non-covalently with molybdate (MoO4 2-) ions. GO:0015337 obsolete low affinity metal ion uptake transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015337 low affinity metal ion uptake transporter activity OBSOLETE. Catalysis of the reaction: Me2+(out) + H+(out) = Me2+(in) + H+(in). Me can be Mn2+ or Cu2+. GO:0015338 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015338 GO:0015339 obsolete cobalt, zinc uptake permease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015339 cobalt, zinc uptake permease activity OBSOLETE. Catalysis of the reaction: (Zn2+ or Co2+)(out) = (Zn2+ or Co2+)(in). The activity is driven by proton motive force, possibly by proton symport. GO:0015333 peptide:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015333 Reactome:R-HSA-427998|RHEA:37047|Reactome:R-HSA-428007 peptide:hydrogen symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: peptide(out) + H+(out) = peptide(in) + H+(in), up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by hydrogen ion movement. GO:0015334 high-affinity oligopeptide transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015334 high-affinity oligopeptide transporter activity|high affinity oligopeptide transporter activity Enables the transfer of oligopeptide from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages. GO:0015335 obsolete heavy metal ion:hydrogen symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015335 heavy metal ion:proton symporter activity|heavy metal ion:hydrogen symporter activity OBSOLETE. Catalysis of the reaction: Me2+(out) + H+(out) = Me2+(in) + H+(in), where Me2+ is Fe2+, Zn2+, Mn2+, Cu2+, Cd2+, Co2+, Ni2+ or Pb2+. GO:0015336 obsolete high affinity metal ion uptake transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015336 high affinity metal ion uptake transporter activity OBSOLETE. Catalysis of the reaction: Me2+(out) + H+(out) = Me2+(in) + H+(in). Me can be Fe2+, Mn2+, Zn2+, Cu2+, Cd2+, Ni2+ or Co2+. GO:0030970 retrograde protein transport, ER to cytosol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030970 protein dislocation from ER|retrograde protein transport, endoplasmic reticulum to cytosol|protein retrotranslocation, ER to cytosol The directed movement of unfolded or misfolded proteins from the endoplasmic reticulum to the cytosol through the translocon. GO:0030971 receptor tyrosine kinase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030971 transmembrane receptor protein tyrosine kinase ligand binding Interacting selectively and non-covalently with a receptor that possesses protein tyrosine kinase activity. GO:0015330 high-affinity glutamine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015330 high affinity glutamine transmembrane transporter activity|high affinity glutamine permease activity Enables the transfer of glutamine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. GO:0015331 obsolete asparagine/glutamine permease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015331 asparagine/glutamine permease activity OBSOLETE. Catalysis of the stereospecific transfer of asparagine or glutamine across a biological membrane. GO:0015332 obsolete leucine/valine/isoleucine permease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015332 leucine/valine/isoleucine permease activity OBSOLETE. (Was not defined before being made obsolete). GO:0030967 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030967 GO:0030968 endoplasmic reticulum unfolded protein response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030968 SREBP-mediated signalling pathway|ER unfolded protein response|erUPR The series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) or other ER-related stress; results in changes in the regulation of transcription and translation. GO:0030965 plasma membrane electron transport, NADH to quinone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030965 The transfer of electrons from NADH to the quinone pool that occurs during oxidative phosphorylation and results in the generation of a proton gradient, mediated by the enzyme known as NADH-quinone oxidoreductase. GO:0030966 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030966 GO:0030963 peptidyl-lysine dihydroxylation to 4,5-dihydroxy-L-lysine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030963 RESID:AA0370 The dihydroxylation of peptidyl-lysine to peptidyl-4,5-dihydroxy-L-lysine. GO:0030964 NADH dehydrogenase complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0030964 Wikipedia:NADH_dehydrogenase NADH dehydrogenase complex (plastoquinone)|plastid NADH dehydrogenase complex (plastoquinone)|Complex I|NADH dehydrogenase complex (quinone)|NADH dehydrogenase complex (ubiquinone)|NADH:plastoquinone reductase complex An integral membrane complex that possesses NADH oxidoreductase activity. The complex is one of the components of the electron transport chain. It catalyzes the transfer of a pair of electrons from NADH to a quinone. GO:0030961 peptidyl-arginine hydroxylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030961 The hydroxylation of peptidyl-arginine to form peptidyl-hydroxyarginine. GO:0030962 peptidyl-arginine dihydroxylation to peptidyl-3,4-dihydroxy-L-arginine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030962 RESID:AA0369 The dihydroxylation of peptidyl-arginine to form peptidyl-3,4-dihydroxy-L-arginine. CHEBI:42266 ethane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_42266 GO:0030969 obsolete mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030969 UFP-specific transcription factor mRNA processing involved in ER UPR|unconventional mRNA splicing involved in UPR|UFP-specific transcription factor mRNA processing involved in endoplasmic reticulum unfolded protein response|XBP1 mRNA splicing, via endonucleolytic cleavage and ligation|XBP1 mRNA splicing under conditions of endoplasmic reticulum (ER) stress|UFP-specific transcription factor mRNA processing during unfolded protein response|unfolded protein response, ligation of mRNA encoding UFP-specific transcription factor by RNA ligase|unconventional splicing of XBP1 mRNA|UFP-specific transcription factor mRNA processing involved in endoplasmic reticulum UPR|UFP-specific transcription factor mRNA processing involved in ER unfolded protein response|HAC1 mRNA splicing|non-spliceosomal mRNA splicing in the unfolded protein response pathway|unfolded protein response, cleavage of primary transcript encoding UFP-specific transcription factor|IRE1-mediated XBP-1 mRNA splicing|Ire1p-mediated HAC-1 mRNA splicing|XBP1 mRNA splicing|spliceosome-independent UFP-specific transcription factor mRNA processing OBSOLETE. The spliceosome-independent cleavage and ligation of the mRNA encoding a UFP-specific transcription factor to remove a single intron, thereby increasing both the translational efficiency of the processed mRNA and the activity of the protein it encodes. GO:0015348 obsolete prostaglandin/thromboxane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015348 prostaglandin/thromboxane transporter activity OBSOLETE. (Was not defined before being made obsolete). GO:0015349 thyroid hormone transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015349 Reactome:R-HSA-9631987|Reactome:R-HSA-879575 Enables the transfer of thyroid hormones from one side of a membrane to the other. Thyroid hormone are any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine. GO:0015344 siderophore uptake transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015344 ferrioxamine uptake transmembrane transporter activity|siderophore-iron uptake transmembrane transporter activity|siderochrome-iron (ferrioxamine) uptake transporter Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: siderophore-iron(ferrioxamine)(out) + H+(out) = siderophore-iron(ferrioxamine)(in) + H+(in). GO:0015345 ferric enterobactin:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015345 ferric-enterobactin:proton symporter activity|ferric enterobactin:hydrogen symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ferric enterobactin(out) + H+(out) = ferric enterobactin(in) + H+(in). GO:0015346 ferric triacetylfusarinine C:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015346 ferric triacetylfusarinine C:hydrogen symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ferric triacetylfusarinine C(out) + H+(out) = ferric triacetylfusarinine C(in) + H+(in). GO:0015347 sodium-independent organic anion transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015347 Reactome:R-HSA-561059|Reactome:R-HSA-879584|Reactome:R-HSA-879594|Reactome:R-HSA-9661723|Reactome:R-HSA-9661799|Reactome:R-HSA-9661397|Reactome:R-HSA-879562|Reactome:R-HSA-9661446 Enables the transfer of organic anions from one side of a membrane to the other, in a sodium independent manner. GO:0015340 obsolete zinc, cadmium uptake permease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015340 zinc, cadmium uptake permease activity OBSOLETE. Catalysis of the reaction: (Zn2+ or Cd2+)(out) = (Zn2+ or Cd2+)(in). The activity is driven by proton motive force, possibly by proton symport. GO:0030960 peptide cross-linking via 3'-(O4'-L-tyrosinyl)-L-tyrosine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030960 RESID:AA0368 The modification of two peptidyl-tyrosines to form a 3'-(O4'-L-tyrosinyl)-L-tyrosine protein cross-link. GO:0015341 zinc efflux active transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015341 zinc efflux permease activity Enables the transfer of a zinc ion or zinc ions from the inside of the cell to the outside of the cell across a membrane: Zn2+(out) = Zn2+(in). The activity is driven by proton motive force. GO:0015342 obsolete zinc, iron permease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015342 zinc, iron permease activity OBSOLETE. Catalysis of the reaction: (Zn2+ or Fe2+)(out) = (Zn2+ or Fe2+)(in), probably powered by proton motive force. CHEBI:17299 4-methylene-L-glutamate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17299 GO:0015343 siderophore transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015343 Reactome:R-HSA-1222597 siderophore transporter activity|siderophore-iron transmembrane transporter activity|siderochrome-iron transporter activity|siderophore-iron transporter activity|siderochrome transporter activity|iron-siderophore transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: siderophore-iron(out) + H+(out) = siderophore-iron(in) + H+(in). CHEBI:17297 UDP-sugar biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17297 CHEBI:17298 dolichyl D-xylosyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17298 CHEBI:17295 L-phenylalanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17295 CHEBI:17296 aniline biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17296 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030956 GatFAB|GatCAB|AdT A protein complex that possesses glutamyl-tRNA(Gln) amidotransferase activity, and therefore creates Gln-tRNA by amidating Glu-tRNA; usually composed of 3 subunits: A, B, and C. Note that the C subunit may not be required in all organisms. GO:0030957 Tat protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030957 Interacting selectively and non-covalently with Tat, a viral transactivating regulatory protein from the human immunodeficiency virus, or the equivalent protein from another virus. GO:0005998 xylulose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0005998 MetaCyc:XYLCAT-PWY xylulose breakdown|xylulose catabolism|xylulose degradation The chemical reactions and pathways resulting in the breakdown of xylulose, the ketopentose threo-2-pentulose. GO:0030954 astral microtubule nucleation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030954 The 'de novo' formation of an astral microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. GO:0030955 potassium ion binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030955 Interacting selectively and non-covalently with potassium (K+) ions. GO:0005999 xylulose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0005999 xylulose anabolism|xylulose synthesis|xylulose formation|xylulose biosynthesis The chemical reactions and pathways resulting in the formation of xylulose, the ketopentose threo-2-pentulose. GO:0030952 establishment or maintenance of cytoskeleton polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030952 cytoskeleton polarization Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures. GO:0005996 monosaccharide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0005996 monosaccharide metabolism The chemical reactions and pathways involving monosaccharides, the simplest carbohydrates. They are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides. GO:0005997 xylulose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0005997 xylulose metabolism The chemical reactions and pathways involving xylulose, the ketopentose threo-2-pentulose. GO:0030953 astral microtubule organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030953 astral microtubule organization and biogenesis|astral microtubule organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of astral microtubules, any of the spindle microtubules that radiate in all directions from the spindle poles. GO:0030950 establishment or maintenance of actin cytoskeleton polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030950 Any cellular process that results in the specification, formation or maintenance of polarized actin-based cytoskeletal structures. GO:0005994 melibiose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0005994 melibiose metabolism The chemical reactions and pathways involving melibiose, the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose. GO:0005995 melibiose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0005995 melibiose degradation|melibiose catabolism|melibiose breakdown The chemical reactions and pathways resulting in the breakdown of melibiose, the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose. GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030951 Any cellular process that results in the specification, formation or maintenance of polarized microtubule-based cytoskeletal structures. GO:0005992 trehalose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0005992 MetaCyc:TRESYN-PWY|MetaCyc:TREHALOSESYN-PWY|MetaCyc:PWY-881 trehalose biosynthesis|trehalose anabolism|mykose biosynthetic process|mykose biosynthesis|trehalose synthesis|trehalose formation|mycose biosynthetic process|mycose biosynthesis The chemical reactions and pathways resulting in the formation of trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi. GO:0005993 trehalose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0005993 MetaCyc:TREDEGLOW-PWY mykose catabolic process|trehalose degradation|trehalose catabolism|trehalose breakdown|mykose catabolism|mycose catabolic process|mycose catabolism The chemical reactions and pathways resulting in the breakdown of trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi. GO:0005990 lactose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0005990 lactose breakdown|lactose catabolism|lactose degradation The chemical reactions and pathways resulting in the breakdown of lactose, the disaccharide galactopyranosyl-glucose. CHEBI:42255 (-)-epigallocatechin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_42255 GO:0005991 trehalose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0005991 mycose metabolism|trehalose metabolism|mycose metabolic process|mykose metabolism|mykose metabolic process The chemical reactions and pathways involving trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi. GO:0015319 sodium:inorganic phosphate symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015319 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + inorganic phosphate(out) = Na+(in) + inorganic phosphate(in). GO:0030958 RITS complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030958 A protein complex required for heterochromatin assembly; contains an Argonaute homolog, a chromodomain protein, and at least one additional protein; named for RNA-induced initiation of transcriptional gene silencing. GO:0030959 peptide cross-linking via 3'-(3'-L-tyrosinyl)-L-tyrosine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030959 RESID:AA0367 The modification of two peptidyl-tyrosines to form a 3'-(3'-L-tyrosinyl)-L-tyrosine protein cross-link. GO:0015315 organophosphate:inorganic phosphate antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015315 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: organophosphate(out) + inorganic phosphate(in) = organophosphate(in) + inorganic phosphate(out). GO:0015316 obsolete nitrite/nitrate porter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015316 nitrite/nitrate porter activity OBSOLETE. (Was not defined before being made obsolete). GO:0015317 phosphate:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015317 phosphate ion carrier activity|phosphate:hydrogen symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phosphate(out) + H+(out) = phosphate(in) + H+(in). GO:0015318 inorganic molecular entity transmembrane transporter activity biolink:MolecularActivity go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0015318 inorganic uptake permease activity|inorganic solute uptake transmembrane transporter activity Enables the transfer of an inorganic molecular entity from the outside of a cell to the inside of the cell across a membrane. An inorganic molecular entity is a molecular entity that contains no carbon. GO:0015311 monoamine:proton antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015311 monoamine:hydrogen antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + monoamine(in) = H+(in) + monoamine(out). GO:0015312 polyamine:proton antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015312 polyamine:hydrogen antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + polyamine(in) = H+(in) + polyamine(out). GO:0015313 fluconazole:proton antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015313 fluconazole:hydrogen antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + fluconazole(in) = H+(in) + fluconazole(out). GO:0015314 aminotriazole:proton antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015314 aminotriazole:hydrogen antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + aminotriazole(in) = H+(in) + aminotriazole(out). GO:0015310 benomyl:proton antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015310 benomyl:hydrogen antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + benomyl(in) = H+(in) + benomyl(out). GO:0030945 protein tyrosine phosphatase activity, via thiol-phosphate intermediate biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030945 The catalysis of phosphate removal from a phosphotyrosine using cysteine as a nucleophile and proceed by means of a thiol-phosphate intermediate. GO:0030946 protein tyrosine phosphatase activity, metal-dependent biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030946 Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate. This reaction requires metal ions. GO:0030943 mitochondrion targeting sequence binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030943 mitochondrial targeting sequence binding Interacting selectively and non-covalently with a mitochondrion targeting sequence, a specific peptide sequence that acts as a signal to localize the protein within the mitochondrion. GO:0030944 DDEL sequence binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030944 Interacting selectively and non-covalently with a KDEL sequence, the C terminus tetrapeptide sequence Asp-Asp-Glu-Leu found in proteins that are to be retained in the endoplasmic reticulum. GO:0030941 chloroplast targeting sequence binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030941 Interacting selectively and non-covalently with a chloroplast targeting sequence, a specific peptide sequence that acts as a signal to localize the protein within the chloroplast. GO:0030942 endoplasmic reticulum signal peptide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030942 ER signal peptide binding Interacting selectively and non-covalently with an endoplasmic reticulum signal peptide, a specific peptide sequence that acts as a signal to localize the protein within the endoplasmic reticulum. GO:0030940 obsolete response to short-day photoperiod biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030940 response to short-day photoperiod OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a photoperiod, an intermittent cycle of light (day) and dark (night) photoperiod regimes, with the dark phase being longer than the light. GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030949 up regulation of vascular endothelial growth factor receptor signaling pathway|positive regulation of VEGF receptor signaling pathway|positive regulation of vascular endothelial growth factor receptor signalling pathway|activation of vascular endothelial growth factor receptor signaling pathway|positive regulation of VEGF receptor signalling pathway|stimulation of vascular endothelial growth factor receptor signaling pathway|up-regulation of vascular endothelial growth factor receptor signaling pathway|upregulation of vascular endothelial growth factor receptor signaling pathway Any process that activates or increases the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity. GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030947 regulation of VEGF receptor signaling pathway|regulation of vascular endothelial growth factor receptor signalling pathway|regulation of VEGF receptor signalling pathway Any process that modulates the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity. GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030948 down regulation of vascular endothelial growth factor receptor signaling pathway|downregulation of vascular endothelial growth factor receptor signaling pathway|negative regulation of vascular endothelial growth factor receptor signalling pathway|negative regulation of VEGF receptor signalling pathway|negative regulation of VEGF receptor signaling pathway|down-regulation of vascular endothelial growth factor receptor signaling pathway|inhibition of vascular endothelial growth factor receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity. GO:0015326 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015326 GO:0015327 cystine:glutamate antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015327 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cystine(out) + glutamate(in) = cystine(in) + glutamate(out). GO:0015328 cystine secondary active transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015328 lysosomal cystine transporter|cystinosin|cystine porter activity Enables the transfer of cystine from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. GO:0015329 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015329 GO:0015322 secondary active oligopeptide transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015322 oligopeptide porter activity Enables the transfer of an oligopeptide or oligopeptides from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction. GO:0015323 obsolete type V protein secretor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015323 type V protein secretor activity OBSOLETE. This term was not defined before being made obsolete. GO:0015324 peptide-acetyl-CoA secondary active transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015324 peptide-acetyl-CoA transporter activity Enables the transfer of peptide-acetyl-CoA from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. GO:0015325 acetyl-CoA:CoA antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015325 Catalysis of the reaction: acetyl-CoA(out) + CoA(in) = acetyl-CoA(in) + CoA(out). GO:0015320 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015320 GO:0015321 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015321 CHEBI:27405 streptidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27405 CHEBI:27406 indole-5,6-quinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27406 CHEBI:27402 (S)-3-hydroxypalmitoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27402 CHEBI:27404 5,6-dihydroxyindole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27404 UBERON:0019042 reproductive system mucosa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0019042 genital mucosa UBERON:0034670 palatal taste bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034670 taste bud of palate A taste bud that is located on the soft palate, in the roof of the mouth. UBERON:0034681 vocal organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034681 Any organ that is the primary organ of vocalization behavior. Examples: The laryngeal vocal cord (humans), the syrinx (birds). CHEBI:27479 2'-hydroxydaidzein biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27479 CHEBI:27475 cyanidin 3-O-beta-D-galactoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27475 CL:0000525 syncytiotrophoblast cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000525 syntrophoblast|plasmidotrophoblast|syncytial trophoblast A cell from the outer syncytial layer of the trophoblast of an early mammalian embryo, directly associated with the maternal blood supply. It secretes hCG in order to maintain progesterone secretion and sustain a pregnancy. CHEBI:27476 beta-D-ribopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27476 CL:0000526 afferent neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000526 input neuron A neuron which conveys sensory information centrally from the periphery. CHEBI:27477 D-valine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27477 CL:0000527 efferent neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000527 output neuron A neuron which sends impulses peripherally to activate muscles or secretory cells. CHEBI:27470 folic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27470 CHEBI:27471 glycodeoxycholic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27471 UBERON:0009678 tooth row biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009678 tooth rows|row of teeth|dental arcade Anatomical cluster consisting of adjacent teeth constituting a row. UBERON:0009679 set of lower jaw teeth biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009679 arcus dentalis inferior|lower jaw teeth|mandibular dental arcade|lower dental arcade|set of all lower teeth A tooth row that is part of a skeleton of lower jaw. CHEBI:27480 phenylacetylglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27480 CL:0000520 prokaryotic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000520 CL:0000521 fungal cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000521 UBERON:0009670 rectal lumen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009670 lumen of rectum An anatomical space that surrounded_by a rectum. CHEBI:52430 N-malonylanthranilic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52430 CHEBI:52432 (24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-en-26-oyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52432 UBERON:0009676 early telencephalic vesicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009676 early telencephalic ventricle|early telencephalic vesicle CHEBI:52424 EC 3.2.1.* (glycosidase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52424 CHEBI:52425 EC 3.2.1.18 (exo-alpha-sialidase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52425 CHEBI:52426 6-(alpha-D-glucosaminyl)-1D-myo-inositol 1,2-cyclic phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52426 CHEBI:27485 prostaglandin J2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27485 CHEBI:27487 3-(imidazol-5-yl)lactic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27487 CHEBI:27482 (R)-coclaurine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27482 UBERON:0009668 ventral mesentery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009668 Ventral mesentery is the part of the peritoneum closest to the navel. UBERON:0009669 embryonic cloacal lumen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009669 An anatomical space that surrounded_by a embryonic cloaca. CHEBI:27491 leukotriene F4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27491 CL:0000530 primary neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000530 CL:0000531 primary sensory neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000531 CHEBI:52421 3-oxohexacosanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52421 UBERON:0009661 midbrain nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009661 Nucleus located in the midbrain. UBERON:0009662 hindbrain nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009662 Nucleus located within the hindbrain. UBERON:0009663 telencephalic nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009663 A nucleus of brain that is part of a telencephalon. UBERON:0009664 gut mesentery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009664 peritoneal cavity mesentary|peritoneal mesentary CHEBI:52417 D-glucosone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52417 CHEBI:27457 undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-D-isoglutaminyl-(glycyl)5-L-lysyl-D-alanyl-D-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27457 CHEBI:27458 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27458 CHEBI:27452 styrene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27452 CL:0000501 granulosa cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000501 granulosa cell of ovary A supporting cell for the developing female gamete in the ovary of mammals. They develop from the coelomic epithelial cells of the gonadal ridge. Granulosa cells form a single layer around the mammalian oocyte in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the ovum in the Graafian follicle. The major functions of granulosa cells include the production of steroids and LH receptors. CHEBI:27453 3-keto-beta-D-galactose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27453 CL:0000502 type D enteroendocrine cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000502 D cell A cell found throughout the gastrointestinal tract and in the pancreas. They secrete somatostatin in both an endocrine and paracrine manner. Somatostatin inhibits gastrin, cholecystokinin, insulin, glucagon, pancreatic enzymes, and gastric hydrochloric acid. A variety of substances which inhibit gastric acid secretion (vasoactive intestinal peptide, calcitonin gene-related peptide, cholecystokinin, beta-adrenergic agonists, and gastric inhibitory peptide) are thought to act by releasing somatostatin. CHEBI:27450 4-(4-deoxy-alpha-D-gluc-4-enosyluronic acid)-D-galacturonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27450 UBERON:0009657 artery of lip biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009657 labial artery UBERON:0009651 nephron tubule basement membrane biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009651 kidney tubule basement membrane|renal tubular basement membrane|renal tubule basement membrane A basement membrane that is part of a nephron tubule. UBERON:0009652 bronchus basement membrane biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009652 bronchial basement membrane A basement membrane that is part of a bronchus. UBERON:0009653 trachea basement membrane biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009653 A basement membrane that is part of a trachea. UBERON:0009655 auricular artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009655 An artery that supplies oxygenated blood to the ear. CHEBI:52402 2,5-diamino-6-(5-phosphono)ribitylamino-4(3H)-pyrimidinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52402 CHEBI:27468 5,6-dihydrothymine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27468 CHEBI:27469 2-dehydro-D-gluconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27469 CL:0000513 cardiac muscle myoblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000513 cardiac muscle progenitor cell|cardiomyocyte progenitor cell A precursor cell destined to differentiate into cardiac muscle cell. CL:0000514 smooth muscle myoblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000514 myoblast, smooth muscle|satellite cell A precursor cell destined to differentiate into smooth muscle myocytes. CL:0000515 skeletal muscle myoblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000515 skeletal myoblast A myoblast that differentiates into skeletal muscle fibers. CHEBI:27466 (S)-3-hydroxytetradecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27466 NCBITaxon:40674 Mammalia organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_40674 mammals|mammals CL:0000517 macrophage derived foam cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000517 A type of foam cell derived from a macrophage containing lipids in small vacuoles and typically seen in atherolosclerotic lesions, as well as other conditions. NCBITaxon:5738 Diplomonadida organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_5738 diplomonads|diplomonads CL:0000519 phagocyte (sensu Nematoda and Protostomia) biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000519 A phagocyte from organisms in the Nematoda or Protostomia clades. NCBITaxon:5739 Hexamitidae organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_5739 UBERON:0009647 tympanic membrane epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009647 tympanic membrane epithelial layer|tympanic epithelium One of the two epithelia which make up the tympanic membrane (along with the fibrous layer) UBERON:0009648 eyelid subcutaneous connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009648 superficial fascia of eyelid A eyelid connective tissue that is part of a hypodermis. CL:0000511 androgen binding protein secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000511 A peptide hormone secreting cell that secretes androgen binding protein. NCBITaxon:5740 Giardia organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_5740 UBERON:0009644 trachea non-cartilage connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009644 CHEBI:27439 (KDO)-lipid IVA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27439 CHEBI:27432 alpha-linolenic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27432 UBERON:0010698 manual digit metacarpus pre-cartilage condensation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010698 hand digit metacarpus pre-cartilage condensation|metacarpus pre-cartilage condensation|metacarpal pre-cartilage condensation|metacarpal bone pre-cartilage condensation|fore limb digit metacarpus pre-cartilage condensation UBERON:0010699 manual digit metacarpus cartilage element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010699 metacarpus cartilage element|fore limb digit metacarpus cartilage element|finger metacarpus cartilage element|metacarpal cartilage element|hand digit metacarpus cartilage element|metacarpal cartilage condensation NCBITaxon:5794 Apicomplexa organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_5794 apicomplexans|apicomplexans CHEBI:27445 maltohexaose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27445 CHEBI:27442 beta-D-fucose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27442 CHEBI:27444 but-3-yn-1-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27444 UBERON:0010696 skeleton of pedal acropodium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010696 phalanges of foot|set of phalanges of pes|posterior acropodium|set of pedal phalanges|foot digit skeleton|posterior acropodium skeleton|set of phalanges of foot|phalanges of pes|hind acropodium skeleton|all phalanges in hindlimb autopod|pedal phalanges The subdivision of the skeleton that consists of all the skeletal elements at the distalmost end of the pedal autopodium - i.e. the bones of the foot or their cartilaginous precursors[cjm]. UBERON:0010697 pedal digit metatarsal cartilage element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010697 hind limb digit metatarsal cartilage condensation|foot digit metatarsal cartilage condensation|metatarsal cartilage condensation UBERON:0010695 mesenchyme of tarsal region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010695 Mesenchyme of the carpal region that contributes to the tarsal skeleton. UBERON:0010687 pedal digit metatarsal pre-cartilage condensation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010687 metatarsus pre-cartilage condensation|hind limb digit metatarsal pre-cartilage condensation|foot digit metatarsal pre-cartilage condensation|metatarsal pre-cartilage condensation|metatarsal bone pre-cartilage condensation UBERON:0010688 skeleton of manual acropodium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010688 fore acropodium skeleton|manual phalanges|anterior acropodium skeleton|phalanges of manus|all phalanges in forelimb autopod|anterior acropodium|phalanges of hand|manual digit skeleton|set of manual phalanges|set of phalanges of manus|set of phalanges of hand|hand digit skeleton The subdivision of the skeleton that consists of all the skeletal elements at the distalmost end of the manual autopodium - i.e. the bones of the hands or their cartilaginous precursors[VSAO,modified]. CHEBI:27417 p-xylene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27417 CHEBI:27418 1,4-naphthoquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27418 UBERON:0010685 pedal digit phalanx cartilage element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010685 hind limb digit phalanx cartilage condensation|foot digit phalanx cartilage element A cartilage element that is part of a pedal digit mesenchyme. UBERON:0010686 manual digit phalanx cartilage element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010686 fore limb digit phalanx cartilage condensation|hand digit phalanx cartilage condensation A cartilage element that is part of a manual digit mesenchyme. CHEBI:340863 2-phospholactic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_340863 CHEBI:27427 5'-dehydroinosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27427 CHEBI:27425 N-acetyl-alpha-D-glucosaminide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27425 UBERON:0009680 set of upper jaw teeth biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009680 set of all upper teeth|upper dental arcade|maxillary dental arcade|upper jaw teeth|arcus dentalis superior A tooth row that is part of a skeleton of upper jaw. CHEBI:27422 (KDO)2-(lauroyl)-lipid IVA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27422 NCBITaxon:5782 Dictyostelium organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_5782 Hyalostilbum GO:1990196 MacAB-TolC complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990196 macrolide transporter MacAB-TolC complex The MacAB-TolC complex is a macrolide transporter complex found in E.coli and related gram-negative bacteria. Its transport activity is specific to macrolide compounds containing 14- and 15-membered lactones. It consists of the dimeric inner membrane ATPase MacB, the hexameric, periplasmic membrane fusion protein MacA and the trimeric outer membrane factor TolC. GO:1990197 ATP-dependent methionine-importing complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990197 MetNIQ transport complex|ATP-binding cassette (ABC) methionine importer complex|MetNI transport complex|methionine transporter|methionine transport complex|MetNIQ complex|ATP-dependent methionine importer complex|MetNI complex|MetNIQ transporter|MetNI transporter|methionine transporter complex, ATP-dependent|MetNI transporter complex|ATP-dependent methionine importing complex|methionine transporter complex|MetNIQ transporter complex An ATP-binding cassette (ABC) transporter complex that is capable of methionine-importing activity. An example is the bacterial MetNIQ methionine transporter, that consists of the dimeric ATPase subunit MetN located at the cytoplasmic side of the plasma membrane and the dimeric transmembrane subunit MetI. MetQ is regarded as the periplasmic methionine-binding chaperon subunit, and is capable of transporting methionine from the periplasm into the cytoplasm in an ATP-dependent manner. GO:1990198 ModE complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990198 ModE dimer A dimeric protein complex containing two ModE subunits. Binds directly to DNA to regulate transcription, and is involved in (positively and negatively) regulating various aspects of molybdenum metabolism. GO:1990199 MsbA transporter complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990199 MsbA dimer|MsbA complex An ATP-binding cassette (ABC) transporter complex made up of a dimer of MsbA. Facilitates the export across the plasma membrane of, amongst others, lipid A and lipopolysaccharide. In contrast to most ABC transporter complexes, each chain of the homodimer contains both the transmembrane domain (TMD) and the cytoplasmic ATP-binding domain (NBD). UBERON:0009708 dorsal pancreas biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009708 pancreatis dorsalis GO:1990192 collecting lymphatic vessel constriction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990192 lymphatic vessel myogenic constriction A decrease in the diameter of collecting lymphatic vessels. GO:1990193 BtuCD complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990193 vitamin B12 transport complex, core subunit|cobalamin transport complex, core subunit|BtuC-BtuD complex Protein complex involved in cobalamin (vitamin B12) transport through the plasma membrane. In E. coli, the complex is a tetramer and consists of the cytoplasmic ATPase BtuD homodimer together with the transmembrane BtuC homodimer. UBERON:0009709 ventral pancreas biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009709 pancreatis ventralis GO:1990194 cytoplasmic U snRNP body assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990194 U body assembly The aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic U snRNP body. GO:1990195 macrolide transmembrane transporter complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990195 MacAB-TolC complex|macrolide transporter complex|AcrAB-TolC complex|macrolide transporter A bacterial transmembrane transporter complex that spans the entire cell membrane system and possesses ATP-dependent xenobiotic transport activity pumping drugs (typically antibiotics) and other toxins directly from the cytosol out of the bacterial cell. Typically, it is trimeric consisting of a inner membrane ATPase (IMP), a periplasmic membrane fusion protein (MFP) and an outer membrane factor (OMF). In E. coli, macrolide transporter complexes may consists of MacB (IMP), MacA (MFP) and TolC (OMF) or AcrB (IMP), AcrA (MFP) and TolC (OMF). Trimeric TolC is a common OMF found in many macrolide transporter complexes. GO:0015418 ABC-type quaternary ammonium compound transporting activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015418 MetaCyc:3.6.3.32-RXN|MetaCyc:RXN-8638|EC:7.6.2.9|RHEA:11036 ATPase-coupled quaternary ammonium compound transmembrane transporting activity|quaternary amine uptake transporter activity|quaternary-ammonium-compound ABC transporter|glycine betaine/proline porter activity|ATP-dependent quaternary-ammonium compound transmembrane transporting activity|quaternary-amine-transporting ATPase activity|quarternary amine transporter activity|quaternary-ammonium-compound-transporting ATPase activity Catalysis of the reaction: ATP + H2O + quaternary ammonium(out) = ADP + H(+) + phosphate + quaternary ammonium(in). GO:0015419 ABC-type sulfate transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015419 RHEA:10192|MetaCyc:3.6.3.25-RXN|EC:3.6.3.25 sulfate transmembrane-transporting ATPase activity|sulphate transporting ATPase activity|sulfate/thiosulfate porter activity|ATPase-coupled sulfate transmembrane transporter activity|sulfate ABC transporter|sulfate-transporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + sulfate(out) = ADP + phosphate + sulfate(in). GO:1990190 peptide-glutamate-N-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990190 Catalysis of the reaction: acetyl-CoA + N-terminal L-glutamate in peptide = CoA + N-acetyl-L-glutamate-peptide. GO:1990191 cobalamin transport complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990191 BtuCDF complex|vitamin B12 transport complex|vitamin B12-transporting BtuCDF complex|cobalamin-transporting BtuCDF complex Protein complex facilitating ATP-dependent cobalamin (vitamin B12) transport through inner cell membrane (periplasm to cytoplasm) in Gram-negative bacteria. In E. coli the system is composed of a periplasmic cobalamin-binding protein (BtuF), an integral membrane homodimer, BtuC, and a cytoplasmic ATP-binding homodimer BtuD. GO:0015414 ABC-type nitrate transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015414 RHEA:13181|MetaCyc:3.6.3.26-RXN|EC:7.3.2.4 nitrate-transporting ATPase activity|nitrate transmembrane-transporting ATPase activity|nitrate transporting ATPase activity|ATPase-coupled nitrate transmembrane transporter activity|nitrate ABC transporter Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + nitrate(out) = ADP + phosphate + nitrate(in). UBERON:0009712 endocardium of right ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009712 right ventricle endocardium|right ventricle endocardial tissue|endocardial lining of right ventricle|right ventricular endocardium Any endocardium that is part of the right ventricle of the heart. GO:0015415 ATPase-coupled phosphate ion transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015415 EC:7.3.2.1|RHEA:24440 ABC phosphate transporter activity|ATP phosphohydrolase (phosphate-importing)|phosphate-transporting ATPase activity|phosphate porter activity|phosphate ABC transporter|phosphate ion transmembrane-transporting ATPase activity|phosphate transporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + phosphate(out) = ADP + phosphate + phosphate(in). GO:0015416 ABC-type phosphonate transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015416 EC:7.3.2.2|MetaCyc:3.6.3.28-RXN|RHEA:18065|MetaCyc:ABC-23-RXN organic phosphonate transmembrane transporter activity|ATPase-coupled alkylphosphonate transmembrane transporter activity|ATPase-coupled organic phosphonate transmembrane transporter activity|alkylphosphonate transmembrane-transporting ATPase activity|phosphonate-transporting ATPase activity|phosphonate ABC transporter|alkylphosphonate transmembrane transporter activity|ATP phosphohydrolase (phosphonate-transporting)|organic phosphonate transmembrane-transporting ATPase activity|alkylphosphonate ABC transporter activity|phosphonate transporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + phosphonate(out) = ADP + phosphate + phosphonate(in). A phosphonate is any salt, anion, or ester of phosphonic acid (HPO(OH)2). UBERON:0009713 endocardium of left ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009713 left ventricle endocardium|left ventricular endocardium|endocardial lining of left ventricle|left ventricle endocardial tissue Any endocardium that is part of the left ventricle of the heart. UBERON:0009714 intermaxillary process biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009714 intermaxillary segment|globular process|globular processes of his The primordial mass of tissue formed by the merging of the medial nasal prominences of the embryo; it contributes to the intermaxillary portion of the upper jaw, the prolabial portion of the upper lip, and the primary palate. GO:0015417 ABC-type polyamine transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015417 EC:7.6.2.11|MetaCyc:ABC-24-RXN|MetaCyc:3.6.3.31-RXN|RHEA:29999 spermidine porter activity|ATPase-coupled polyamine transmembrane transporter activity|ATP-dependent polyamine transmembrane transporter activity|polyamine porter activity|polyamine-transporting ATPase activity|polyamine-importing ATPase activity|polyamine ABC transporter|spermidine-importing ATPase activity|ATPase-coupled spermidine transmembrane transporter activity Catalysis of the reaction: ATP + H2O + polyamine(out) = ADP + phosphate + polyamine(in). CHEBI:52392 2-arachidonoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52392 CHEBI:134542 oxodocosahexaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134542 CHEBI:76360 (2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76360 GO:0015410 manganese transmembrane transporter activity, phosphorylative mechanism biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015410 RHEA:17365|MetaCyc:3.6.3.35-RXN|Reactome:R-HSA-5692462|EC:7.2.2.5 manganese-transporting ATPase activity|ABC-type Mn(2+) transporter|manganese ABC transporter|ATP-dependent manganese transmembrane transporter activity|ATPase-coupled manganese transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Mn2+(out) = ADP + phosphate + Mn2+(in). UBERON:0009715 stomodeal lumen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009715 lumen of stomodeum|stomatodeal cavity|lumen of stomatodaeum An anatomical cavity that surrounded_by a stomodeum. GO:0015411 ABC-type taurine transporter transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015411 MetaCyc:3.6.3.36-RXN|EC:7.6.2.7|RHEA:14614 taurine-transporting ATPase activity|ATPase-coupled taurine transporter activity|taurine ABC transporter|ATP-dependent taurine transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + taurine(out) = ADP + phosphate + taurine(in). GO:0015412 ABC-type molybdate transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015412 RHEA:22020|MetaCyc:3.6.3.29-RXN|EC:7.3.2.5 molybdate-transporting ATPase activity|molybdate ABC transporter|molybdate transmembrane-transporting ATPase activity|molybdate porter activity|molybdate transporting ATPase activity|ATPase-coupled molybdate transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + molybdate(out) = ADP + phosphate + molybdate(in). GO:0015413 ABC-type nickel transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015413 MetaCyc:3.6.3.24-RXN|MetaCyc:ABC-20-RXN|RHEA:15557|EC:7.2.2.11 nickel porter activity|nickel transporting ATPase activity|nickel ABC transporter|ATP-dependent nickel transmembrane transporter activity|ATPase-coupled nickel transmembrane transporter activity|nickel-transporting ATPase activity|nickel ABC transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ni2+(out) = ADP + phosphate + Ni2+(in). CHEBI:76364 (2E,6Z,9Z,12Z,15Z,18Z)-tetracosahexaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76364 CHEBI:76368 (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76368 CHEBI:52393 episterol ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52393 CHEBI:134540 N-acylphytosphingosine 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134540 CHEBI:52394 lanosteryl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52394 CHEBI:76366 (3S,6Z,9Z,12Z,15Z,18Z)-3-hydroxytetracosapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76366 CHEBI:52395 oxyketone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52395 CHEBI:52396 alpha-oxyketone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52396 CHEBI:76367 (6Z,9Z,12Z,15Z,18Z)-3-oxotetracosapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76367 GO:0015429 obsolete peroxisomal fatty acyl transporter biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015429 peroxisomal fatty acyl transporter OBSOLETE. (Was not defined before being made obsolete). GO:0015425 ATPase-coupled nonpolar-amino acid transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015425 EC:7.4.2.2|TC:3.A.1.4.1|MetaCyc:3.6.3.22-RXN nonpolar-amino-acid-transporting ATPase activity|nonpolar-amino acid ABC transporter|nonpolar amino acid-transporting ATPase activity|ATP-dependent nonpolar-amino acid transporter activity|nonpolar-amino acid-transporting ATPase activity|leucine/isoleucine/valine porter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + nonpolar amino acid(out) = ADP + phosphate + nonpolar amino acid(in). GO:0015426 ATPase-coupled polar amino acid-transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015426 EC:7.4.2.1|RHEA:14673|MetaCyc:3.6.3.21-RXN polar amino acid uptake transporter activity|polar-amino acid-importing ATPase activity|ATP-dependent polar amino acid-transporter activity|histidine/arginine/lysine/ornithine porter activity|polar-amino acid-transporting ATPase activity|polar-amino acid ABC transporter|polar amino acid-importing ATPase activity|polar-amino-acid-transporting ATPase activity|cystine/diaminopimelate porter activity|histidine permease activity|glutamate/aspartate porter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + polar amino acid(out) = ADP + phosphate + polar amino acid(in). GO:0015427 obsolete ABC-type efflux porter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015427 ABC-type efflux porter activity OBSOLETE. (Was not defined before being made obsolete). CHEBI:52381 hexadec-2-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52381 GO:0015428 obsolete type I protein secretor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015428 type I protein secretor activity OBSOLETE. This term was not defined before being made obsolete. GO:0015421 ABC-type oligopeptide transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015421 EC:7.4.2.6|Reactome:R-HSA-5223317|RHEA:37271|MetaCyc:3.6.3.23-RXN ABC-type oligopeptide transporter|ATP-dependent oligopeptide transmembrane transporter activity|oligopeptide permease activity|ATPase-coupled oligopeptide transmembrane transporter activity|oligopeptide-transporting ATPase activity|oligopeptide ABC transporter Catalysis of the reaction: ATP + H2O + oligopeptide(out) = ADP + phosphate + oligopeptide(in). GO:0015422 ABC-type oligosaccharide transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015422 EC:7.5.2.2|MetaCyc:3.6.3.18-RXN ABC-type oligosaccharide transporter|oligosaccharide-transporting ATPase activity|oligosaccharide ABC transporter|ATPase-coupled oligosaccharide transmembrane transporter activity|ATP-dependent oligosaccharide transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + oligosaccharide(out) = ADP + phosphate + oligosaccharide(in). GO:0015423 ABC-type maltose transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015423 EC:7.5.2.1|RHEA:22132|MetaCyc:3.6.3.19-RXN ABC-type maltose transporter|ATPase-coupled maltose transmembrane transporter activity|ATP-dependent maltose transmembrane transporter activity|maltooligosaccharide-importing ATPase activity|maltose-transporting ATPase activity|maltose ABC transporter Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + maltose(out) = ADP + phosphate + maltose(in). GO:0015424 ATPase-coupled amino acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015424 amino acid-exporting ATPase activity|ATP-dependent amino acid transmembrane transporter activity|amino acid-importing ATPase activity|amino acid-transporting ATPase activity|amino acid ABC transporter Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + amino acid(out/in) = ADP + phosphate + amino acid(in/out). CHEBI:52386 zymosterol intermediate 2 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52386 CHEBI:76375 (R)-3-hydroxydocosanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76375 CHEBI:52388 4-hydroxymethylzymosterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52388 CHEBI:76373 (R)-3-hydroxyicosanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76373 GO:0015420 ABC-type vitamin B12 transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015420 Reactome:R-HSA-3000238|MetaCyc:ABC-5-RXN|EC:7.6.2.8|Reactome:R-HSA-3095901|RHEA:17873|Reactome:R-HSA-3315437|MetaCyc:3.6.3.33-RXN vitamin B12 porter activity|cobalamin ABC transporter|cobalamin-transporting ATPase activity|cobalamin porter activity|vitamin B12 ABC transporter activity|ATPase-coupled cobalamin transmembrane transporter activity|vitamin B12-transporting ATPase activity|cobalamin transporter activity|ATP-dependent vitamin B12 transmembrane transporter activity|vitamin B12 transporter activity|ATP-dependent cobalamin transmembrane transporter activity|ATPase-coupled vitamin B12 transmembrane transporter activity Catalysis of the reaction: ATP(4-) + cob(I)alamin + H2O <=> ADP(3-) + hydrogenphosphate + cob(I)alamin + H+. Cobalamin is also known as vitamin B12. CHEBI:76374 (R)-3-hydroxystearoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76374 CHEBI:76377 (3R)-3-hydroxytetracosanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76377 CHEBI:76378 (R)-3-hydroxyhexacosanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76378 CHEBI:134529 omega-(methylthio)-2-oxocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134529 CHEBI:134527 alpha-D-Gal-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134527 CL:0000584 enterocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000584 An epithelial cell that has its apical plasma membrane folded into microvilli to provide ample surface for the absorption of nutrients from the intestinal lumen. CHEBI:76382 (R)-3-hydroxyoctacosanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76382 CHEBI:76383 trans-2-octacosenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76383 CHEBI:134526 S-(long-chain fatty acyl)-L-cysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134526 CL:0000586 germ cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000586 The reproductive cell in multicellular organisms. CL:0000588 odontoclast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000588 A specialized osteoclast associated with the absorption and removal of cementum. CHEBI:76386 triacontanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76386 CHEBI:76387 (3R,11Z)-3-hydroxyicosenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76387 CHEBI:76384 (R)-3-hydroxytriacontanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76384 CHEBI:76385 trans-2-triacontenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76385 CHEBI:52371 N-(2-hydroxytetracosanoyl)sphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52371 CHEBI:52372 N-(2-hydroxyhexacosanoyl)sphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52372 CHEBI:76388 (2E,11Z)-icosadienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76388 CHEBI:52373 N-(2-hydroxytetracosanoyl)phytosphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52373 CHEBI:76389 (3R,13Z)-3-hydroxydocosenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76389 CHEBI:52374 N-(2-hydroxyhexacosanyl)-(4R)-phytosphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52374 GO:0015407 ATPase-coupled monosaccharide transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015407 EC:3.6.3.17|RHEA:29900|MetaCyc:3.6.3.17-RXN monosaccharide-transporting ATPase activity|monosaccharide-importing ATPase activity|ATP phosphohydrolase (monosaccharide-importing)|ATP-dependent monosaccharide transmembrane transporter activity|monosaccharide ABC transporter Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + monosaccharide(out) = ADP + phosphate + monosaccharide(in). Ribose, xylose, arabinose, galactose and methylgalactoside are imported. GO:0015408 ABC-type ferric iron transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015408 MetaCyc:3.6.3.30-RXN|EC:7.2.2.7|RHEA:12332 ATPase-coupled ferric iron transmembrane transporter activity|ferric transporting ATPase activity|ferric ABC transporter|Fe3+-transporting ATPase activity|ABC-type Fe3+ transporter|ferric-transporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Fe3+(out) = ADP + phosphate + Fe3+(in). GO:0015409 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015409 GO:0015403 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015403 CHEBI:134532 3-(omega-methylthio)alkylmalic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134532 CHEBI:134533 3-(2-methylthioethyl)malic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134533 GO:0015404 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015404 CL:0000593 androgen secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000593 A steroid hormone secreting cell that secretes androgen. GO:0015405 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015405 CL:0000594 skeletal muscle satellite cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000594 An elongated, spindle-shaped, cell that is located between the basal lamina and the plasmalemma of a muscle fiber. These cells are mostly quiescent, but upon activation they divide to produce cells that generate new muscle fibers. CHEBI:134530 2-(omega-methylthio)alkylmalic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134530 GO:0015406 obsolete ABC-type uptake permease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015406 ABC-type uptake permease activity OBSOLETE. (Was not defined before being made obsolete). CL:0000595 enucleate erythrocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000595 red blood cell|RBC An erythrocyte lacking a nucleus. CHEBI:134531 polyunsaturated dicarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134531 CL:0000596 sexual spore biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000596 meiotically-derived spore A spore formed following meiosis. Sometimes following meiosis, prospores may undergo one or more rounds of mitosis before they are fully mature. CHEBI:76393 (2E,15Z)-tetracosadienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76393 CHEBI:134536 2-(2-methylthiopropyl)maleic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134536 CHEBI:134537 3-(3-methylthio)propylmalic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134537 GO:0015400 low-affinity secondary active ammonium transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015400 low affinity ammonium transmembrane transporter activity|low affinity secondary active ammonium transmembrane transporter activity Enables the transfer of ammonium from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations. CL:0000598 pyramidal neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000598 pyramidal cell|projection neuron|pyramidal neuron Pyramidal neurons have a pyramid-shaped soma with the apex and an apical dendrite pointed toward the pial surface and other dendrites and an axon emerging from the base. The axons may have local collaterals but also project outside their region. Pyramidal neurons are found in the cerebral cortex, the hippocampus, and the amygdala. GO:0015401 urea:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015401 urea active transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: urea(out) + Na+(out) = urea(in) + Na+(in). CHEBI:76391 (2E,13Z)-docosadienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76391 CHEBI:134534 2-(omega-methylthio)alkylmaleic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134534 CHEBI:134535 2-(2-methylthio)ethylmaleic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134535 GO:0015402 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015402 CHEBI:76392 (3R,15Z)-3-hydroxytetracosenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76392 CL:0000599 conidium biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000599 An asexual, nonmotile spore formed by higher fungi; conidia are usually made from the side or tip of specialized sporogenous cells and do not form by progressive cleavage of the cytoplasm. CHEBI:52360 1,2-dioleoyl-sn-glycero-3-phosphocholine(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52360 CHEBI:52362 ortho-fused heteroarene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52362 GO:1990156 DnaB-DnaG complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990156 DnaB-DnaG primosome complex A protein complex containing homohexameric DnaB helicase, and DnaG (a primase). Facilitates the unwinding of double-stranded DNA and the synthesis of RNA primer sequences during DNA replication and repair in Prokaryotes. GO:1990157 DnaA-DnaB-DnaC complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990157 A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC bound to the DNA-bound DNA replication initiation protein DnaA. Essential for DNA replication initiation. GO:1990158 DnaB-DnaC-DnaT-PriA-PriB complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990158 phi-X174-type preprimosome|DnaB-DnaC-DnaT-PriA-PriB preprimosome A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC, replication restart proteins DnaT, PriA and PriB, and associated DNA. Involved in the restart of DNA replication after a stalled replication fork has been repaired. GO:1990159 DnaB-DnaC-DnaT-PriA-PriC complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990159 phi-X174-type preprimosome|DnaB-DnaC-DnaT-PriA-PriC preprimosome A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC, replication restart proteins DnaT, PriA and PriC, and associated DNA. Involved in the restart of DNA replication after a stalled replication fork has been repaired. GO:1990152 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990152 GO:1990153 maintenance of protein localization to heterochromatin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990153 maintenance of protein localisation to heterochromatin|maintenance of protein location in heterochromatin A process in which a protein is maintained in a location in telomeric heterochromatin. GO:1990154 enzyme IIA-maltose transporter complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990154 EIIA(Glc)-maltose transporter complex|maltose transporter inhibitor complex|EIIA(Glc)-MalFGK2 complex A protein complex consisting of the pentameric maltose transporter complex bound to two enzyme IIA (EIIA) molecules. EIIA is a component of the glucose-specific phosphotransferase system that inhibits maltose transport from the periplasm to the cytoplasm. When EIIA-bound, the maltose transporter remains in the open, inward-facing conformation, which prevents binding of maltose-loaded maltose binding protein (MBP) to the transporter. GO:1990155 Dsc E3 ubiquitin ligase complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990155 Dsc complex assembly The aggregation, arrangement and bonding together of a set of components to form a Dsc E3 ubiquitin ligase complex, an E3 ubiquitin ligase complex localized to the ER and Golgi membrane. CL:0000568 amine precursor uptake and decarboxylation cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000568 APUD cell A cell that originates in the neural crest, that has certain cytochemical and ultrastructural characteristics and is found scattered throughout the body; types include melanocytes, the cells of the chromaffin system, and cells in the hypothalamus, hypophysis, thyroid, parathyroids, lungs, gastrointestinal tract, and pancreas. This cell type concentrates the amino acid precursors of certain amines and decarboxylate them, forming amines that function as regulators and neurotransmitters. This cell type produces substances such as epinephrine, norepinephrine, dopamine, serotonin, enkephalin, somatostatin, neurotensin, and substance P, the actions of which may affect contiguous cells, nearby groups of cells, or distant cells, thus functioning as local or systemic hormones. The name is an acronym for amine precursor uptake and decarboxylation cell. CHEBI:27398 imidazole-4-acetaldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27398 CL:0000569 cardiac mesenchymal cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000569 A mesenchymal cell found in the developing heart and that develops into some part of the heart. These cells derive from intra- and extra-cardiac sources, including the endocardium, epicardium, neural crest, and second heart field. GO:1990150 VEGF-A complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990150 vascular endothelial growth factor A complex A homodimeric, extracellular protein complex containing two VEGF-A monomers. Binds to and activates a receptor tyrosine kinase. GO:1990151 protein localization to cell tip biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990151 protein localisation to cell tip A process in which a protein is transported to, or maintained in, a location at the cell tip. UBERON:0010740 bone of appendage girdle complex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010740 bone of extended limb/fin region|limb bone A bone that is part of an appendage girdle complex (i.e. any bone in a limb, fin or girdle). UBERON:0010741 bone of pectoral complex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010741 bone of forelimb or pectoral fin or pectoral girdle|wing bone|forelimb bone A bone that is part of a pectoral complex. Examples: scapula, manus phalanx, any carpal bone, any bone of the pectoral fin. CHEBI:27394 D-erythro-3-methylmalic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27394 CHEBI:134509 13,14-dihydro-15-keto-PGF1alpha biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134509 CL:0000561 amacrine cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000561 amacrine neuron Interneuron of the vertebrate retina. They integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. They lack large axons. CL:0000562 nucleate erythrocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000562 red blood cell|RBC An erythrocyte having a nucleus. UBERON:0009758 abdominal ganglion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009758 A ganglion that is part of a abdominal segment of trunk. CL:0000563 endospore biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000563 bacterial spore A rounded, inactive form that certain bacteria assume under conditions of extreme temperature, dryness, or lack of food. The bacterium develops a waterproof cell wall that protects it from being dried out or damaged. CL:0000564 neutrophilic promyelocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000564 neutrophilic premyelocyte|neutrophilic progranulocyte A promyelocyte committed to the neutrophil lineage. This cell type is GATA-1-positive, C/EBPa-positive, AML-1-positive, MPO-positive, has low expression of PU.1 transcription factor and lacks lactotransferrin expression. CL:0000566 angioblastic mesenchymal cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000566 angioblast|chondroplast A mesenchymal stem cell capable of developing into blood vessel endothelium. CHEBI:134502 phosphatidylethanolamine 40:0 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134502 UBERON:0009751 cardiac mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009751 heart mesenchyme The embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing cardiac structures CHEBI:52350 3-oxoicosanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52350 UBERON:0009752 pancreas mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009752 The embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing pancreas CHEBI:52351 3-oxodocosanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52351 CHEBI:52352 3-oxotetracosanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52352 GO:1990167 protein K27-linked deubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990167 A protein deubiquitination process in which a K27-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 27 of the ubiquitin monomers, is removed from a protein. GO:1990168 protein K33-linked deubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990168 A protein deubiquitination process in which a K33-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 33 of the ubiquitin monomers, is removed from a protein. GO:1990169 stress response to copper ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990169 response to copper ion stress|stress response to copper|response to copper toxicity Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a copper ion stimulus. GO:1990163 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990163 GO:1990164 histone H2A phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990164 The modification of histone H2A by the addition of a phosphate group. CHEBI:52347 3-hydroxyicosanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52347 CHEBI:52348 3-hydroxydocosanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52348 GO:1990165 single-strand break-containing DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990165 single-strand break-containing damaged DNA binding|SSB-containing DNA binding Interacting selectively and non-covalently with damaged DNA containing single-strand breaks (SSBs). GO:1990166 protein localization to site of double-strand break biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990166 protein localisation to site of double-strand break|protein localization to site of DSB|protein localization to double-strand break site Any process in which a protein is transported to, or maintained at, a region of a chromosome at which a DNA double-strand break has occurred. GO:1990160 DnaB-DnaC-Rep-PriC complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990160 DnaB-DnaC-Rep-PriC preprimosome|phi-X174-type preprimosome A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC, replication restart proteins Rep and PriC, and associated DNA. Involved in the restart of DNA replication after a stalled replication fork has been repaired. CL:0000579 border follicle cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000579 GO:1990161 DnaB helicase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990161 DnaB hexamer A homohexameric protein complex that possesses DNA helicase activity; functions during DNA replication and repair. GO:1990162 histone deacetylase activity (H3-K4 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990162 Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 4) + H2O = histone H3 L-lysine (position 4) + acetate. This reaction represents the removal of an acetyl group from lysine at position 4 of the histone H3 protein. CL:0000570 parafollicular cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000570 parafollicular cell of thyroid gland|C cell of thyroid gland|C cell|thyroid parafollicular cell|clear cell of thyroid gland A neuroepithelial cells that occurs singly or in small groups, close to the outer follicular borders but within the follicular basement membrane of the thyroid. Expresses a form of the neural cell adhesion molecule (N-CAM) on their surface. Secretes calcitonin, 5-hydroxytryptamine and dopamine. UBERON:0009744 lymph node medullary sinus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009744 medullary sinus|lymph node medullary sinusoid The channels in the lymph node medulla that separate the medullary cords and are crossed by a reticulum of cells and fibers and bounded by littoral cells; lymph flows through the medullary sinus from the cortical sinuses and into the efferent lymphatic vessels CL:0000571 leucophore biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000571 A pigment cell derived from the neural crest. Contains uric acid or other purine crystals deposited in stacks called leucosomes. The crystals reflect light and this gives a white appearance under white light. UBERON:0009745 lymph node medullary cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009745 medullary cord The dense rope-like structures of lymphatic tissue located between the medullary sinuses in the medulla of a lymph node UBERON:0010720 hindlimb zeugopod skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010720 hind epipodium|skeleton cruris|posterior zeugopodium|hindlimb zygopod skeleton|posterior zeugopodium skeleton|crus skeleton|hindlimb epipodium|crural skeleton|mesomere 2 of pelvic appendage Subdivision of skeleton consisting of all skeletal elements in an hindlimb zeugopod region. Typically consists of the tibia and the fibula. CL:0000573 retinal cone cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000573 One of the two photoreceptor cell types in the vertebrate retina. In cones the photopigment is in invaginations of the cell membrane of the outer segment. Cones are less sensitive to light than rods, but they provide vision with higher spatial and temporal acuity, and the combination of signals from cones with different pigments allows color vision. CL:0000574 erythrophore biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000574 A pigment cell derived from the neural crest. Contains pteridine and/or carotenoid pigments in structures called pterinosomes or erythrosomes. This gives an orange to red appearance. CL:0000575 corneal epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000575 epithelial cell of cornea An epithelial cell of the cornea. UBERON:0009749 limb mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009749 limb mesoderm The primordial embryonic connective tissue of the developing limbs, autopods and digits, consisting of mesenchymal cells supported in interlaminar jelly, that derive mostly from the mesoderm and contribute to limb connective tissue, bone and musculature in conjunction with myotome cells. CL:0000576 monocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000576 Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells. CHEBI:52342 ethyl formate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52342 CHEBI:52343 formate ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52343 UBERON:0010728 sphenoid lesser wing pre-cartilage condensation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010728 A orbitosphenoid endochondral element that is composed primarily of a pre-cartilage condensation. CHEBI:52340 tricyclic triterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52340 GO:1990178 HU-DNA complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990178 HU complex A protein-DNA complex that consists of HU heterodimers (an alpha and a beta chain) assembled into octamers along DNA. HU binds to double-stranded DNA in a structure- and sequence-specific manner and bends the DNA into a nucleosome-like structure. GO:1990179 protein localization to actomyosin contractile ring biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990179 protein localisation to actomyosin contractile ring A process in which a protein is transported to, or maintained at, the actomyosin contractile ring. GO:1990174 phosphodiesterase decapping endonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990174 G(5')pppN pyrophosphatase activity Catalysis of the removal of the cap from an unmethylated 5'-end capped RNA resulting in the release of the entire cap structure (GpppN) and a 5' monophosphorylated RNA. CHEBI:27379 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27379 GO:1990175 EH domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990175 Interacting selectively and non-covalently with an EH domain of a protein. The EH stand for Eps15 homology. This was originally identified as a motif present in three copies at the NH2-termini of Eps15 and of the related molecule Eps15R. GO:1990176 MalFGK2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990176 MalFGK(2) complex|MalF-MalG-MalK-MalK complex|MalF-MalG-MalK(2) complex|maltose transport MalFGK2 complex|maltose transport complex, core subunit Protein complex involved in maltose transport through the plasma membrane. In E. coli, the complex is a tetramer and consists of a cytoplasmic ATPase MalK homodimer together with a heterodimeric transmembrane subunit MalF-MalG. GO:1990177 IHF-DNA complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990177 IHFa-IHFb-DNA complex|IHF complex A protein-DNA complex containing IHF heterodimers (an alpha and a beta chain) bound to DNA. IHF binds to double-stranded DNA in a structure- and sequence-specific manner and bends the DNA into a nucleosome-like structure, the bacterial nucleoid. CL:0000545 T-helper 1 cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000545 Th1 cell|T helper cells type 1|Th1 T-cell|Th1 T-lymphocyte|Th1 CD4+ T cell|Th1 T cell|Th1 T lymphocyte|helper T cell type 1|T(H)-1 cell A CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive, CXCR3-positive, CCR6-negative, and is capable of producing interferon-gamma. GO:1990170 stress response to cadmium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990170 response to cadmium ion stress|response to cadmium toxicity|stress response to cadmium Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a cadmium ion stimulus. CL:0000546 T-helper 2 cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000546 T(H)-2 cell|Th2 cell|T helper cells type 2|Th2 T-cell|Th2 T-lymphocyte|Th2 T cell|Th2 T lymphocyte|helper T cell type 2 A CD4-positive, alpha-beta T cell that has the phenotype GATA-3-positive, CXCR3-negative, CCR6-negative, and is capable of producing interleukin-4. GO:1990171 SCF complex disassembly in response to cadmium stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990171 The disaggregation of the SCF ubiquitin ligase complex in response to cadmium stress. CHEBI:27376 methanesulfonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27376 GO:1990172 G protein-coupled receptor catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990172 G-protein coupled receptor catabolic process The chemical reactions and pathways resulting in the breakdown of a G protein-coupled receptor. CL:0000547 proerythroblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000547 rubriblast|pronormoblast An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers. GO:1990173 protein localization to nucleoplasm biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990173 nucleolus to nucleoplasm transport|protein localisation to nucleoplasm A process in which a protein is transported to, or maintained in, a location within the nucleoplasm. CL:0000548 animal cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000548 CHEBI:27378 (2S,3R)-aldopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27378 CL:0000549 basophilic erythroblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000549 early normoblast|early erythroblast|basophilic normoblast|prorubricyte A nucleated immature erythrocyte, having cytoplasm generally similar to that of the earlier proerythroblast but sometimes even more basophilic, and usually regular in outline. The nucleus is still relatively large, but the chromatin strands are thicker and more deeply staining, giving a coarser appearance; the nucleoli have disappeared. This cell is CD71-positive and lacks hematopoeitic lineage markers. CHEBI:27372 1D-chiro-inositol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27372 CHEBI:27374 1L-chiro-inositol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27374 UBERON:0010711 pelvic fin skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010711 Paired fin skeleton located in the abdominal position that consists of supporting endochondral radialsB and dermal fin rays or lepidotrichia. UBERON:0010712 limb skeleton subdivision biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010712 Skeletal subdivision that is a segment of the limb skeleton. CHEBI:27380 (1->6)-beta-D-glucan biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27380 UBERON:0010710 pectoral fin skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010710 forefin skeleton Paired fin skeleton that consists of the supporting endochondral proximal and distal radials and the dermal fins rays or lepidotrichia. The pectoral fin skeleton is located in the thoracic region of the body and articulates with the scapula and coracoid. CL:0000540 neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000540 nerve cell The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system. CHEBI:27381 2,2',3-trihydroxydiphenyl ether biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27381 CL:0000541 melanoblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000541 A cell that originates from the neural crest and differentiates into a pigment cell. CL:0000542 lymphocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000542 A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin. UBERON:0010713 paired fin skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010713 The collection of all skeletal elements in a single paired fin. UBERON:0010719 girdle skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010719 skeleton of girdle The subdivision of the skeleton of either the pectoral or pelvic girdle. CHEBI:52333 1,2-dioleoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52333 CHEBI:52330 glycerophosphatidylethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52330 GO:1990189 peptide-serine-N-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990189 Catalysis of the reaction: acetyl-CoA + N-terminal L-serine in peptide = CoA + N-acetyl-L-serine-peptide. CHEBI:52328 3-oxodocosanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52328 CHEBI:52329 3-oxotetracosanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52329 CHEBI:52324 3-hydroxyicosanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52324 GO:1990185 regulation of lymphatic vascular permeability biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990185 Any process that modulates the extent to which lymphatic vessels can be pervaded by fluid. GO:1990186 regulation of lymphatic vessel size biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990186 regulation of collecting lymphatic vessel size Any process that modulates the size of lymphatic vessels. CHEBI:52325 3-hydroxydocosanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52325 GO:1990187 obsolete protein localization to mRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990187 protein localization to mRNA OBSOLETE. A process in which a protein is transported to, or maintained at mRNA. GO:1990188 euchromatin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990188 Interacting selectively and non-covalently with euchromatin, a dispersed and relatively uncompacted form of chromatin. CHEBI:52327 3-oxoicosanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52327 CL:0000556 megakaryocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000556 megalokaryocyte|megacaryocyte|megalocaryocyte A giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow; mature blood platelets are released from its cytoplasm. GO:1990181 acetyl-CoA biosynthetic process from pantothenate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990181 acetyl-CoA anabolism from pantothenate|acetyl-CoA synthesis from pantothenate|acetyl-CoA formation from pantothenate The chemical reactions and pathways resulting in the formation of acetyl-CoA from pantothenate via phosphopantothenate and CoA. CHEBI:27386 cinnamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27386 GO:1990182 exosomal secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990182 multi-vesicular body fusion with plasma membrane|exosomal secretory pathway|secretion of exosome|extracellular vesicular exosome secretion|exosomal protein secretion The process whereby a membrane-bounded vesicle is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. CL:0000557 granulocyte monocyte progenitor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000557 granulocyte-macrophage progenitor|granulocyte/monocyte precursor|GMP|colony forming unit granulocyte macrophage|CFU-C , Colony forming unit in culture|CFU-GM|granulocyte/monocyte progenitor A hematopoietic progenitor cell that is committed to the granulocyte and monocyte lineages. These cells are CD123-positive, and do not express Gata1 or Gata2 but do express C/EBPa, and Pu.1. CL:0000558 reticulocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000558 An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds. GO:1990183 lymphatic vascular process in circulatory system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990183 A circulatory process that occurs at the level of the lymphatic vasculature. GO:1990184 amino acid transport complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990184 A heteromeric protein complex consisting of a multi-transmembrane spanning subunit (the light chain) and a type II glycoprotein subunit (the heavy chain) that functions to transport amino acids across a plasma membrane. CL:0000559 promonocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000559 A precursor in the monocytic series, being a cell intermediate in development between the monoblast and monocyte. This cell is CD11b-positive and has fine azurophil granules. CHEBI:27389 3-aminoisobutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27389 CHEBI:27384 3-(4-oxo-4,5-dihydro-1H-imidazol-5-yl)propanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27384 CHEBI:27385 tetrachloromethane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27385 GO:1990180 mitochondrial tRNA 3'-end processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990180 tRNA 3' processing in mitochondrion|tRNA 3' processing in mitochondria|tRNA 3'-end processing in mitochondria The process in which the 3' end of a pre-tRNA molecule is converted to that of a mature tRNA in the mitochondrion. UBERON:0009722 entire pharyngeal arch endoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009722 pharyngeal arch endoderm UBERON:0010700 phalanx pre-cartilage condensation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010700 UBERON:0010701 phalanx cartilage element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010701 phalanx cartilage condensation CHEBI:27390 omega-aminoaldehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27390 CL:0000550 polychromatophilic erythroblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000550 polychromatophilic normoblast|polychromatic erythroblast|intermediate normoblast|intermediate erythroblast|rubricyte|polychromatic normoblast A nucleated, immature erythrocyte in which the nucleus occupies a relatively smaller part of the cell than in its precursor, the basophilic erythroblast. The cytoplasm is beginning to acquire hemoglobin and thus is no longer a purely basophilic, but takes on acidophilic aspects, which becomes progressively more marked as the cell matures. The chromatin of the nucleus is arranged in coarse, deeply staining clumps. This cell is CD71-positive and lacks hematopoeitic lineage markers. CHEBI:27391 1-pyrroline-3-hydroxy-5-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27391 CHEBI:27392 UDP-3-O-(3-hydroxytetradecanoyl)-D-glucosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27392 CL:0000552 orthochromatic erythroblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000552 acidophilic erythroblast|late erythoblast|eosinophilic erythroblast|orthochromatic normoblast|pyknotic eto enrythroblast The final stage of the nucleated, immature erythrocyte, before nuclear loss. Typically the cytoplasm is described as acidophilic, but it still shows a faint polychromatic tint. The nucleus is small and initially may still have coarse, clumped chromatin, as in its precursor, the polychromatophilic erythroblast, but ultimately it becomes pyknotic, and appears as a deeply staining, blue-black, homogeneous structureless mass. The nucleus is often eccentric and sometimes lobulated. CL:0000553 megakaryocyte progenitor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000553 promegakaryocyte|CFU-Meg|colony-forming unit-megakaryocyte|MkP|megacaryocyte progenitor cell|promegacaryocyte|megakaryocytic progenitor cell|Meg-CFC|megacaryoblast|megakaryoblast The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative). UBERON:0010702 digit mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010702 digital ray Mesenchyme of the digit region. UBERON:0010703 forelimb zeugopod skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010703 fore epipodium|antebrachial skeleton|mesomere 2 of pectoral appendage|forearm skeleton|wing zeugopod skeleton|skeleton of forearm|anterior zeugopodium skeleton|antebrachium skeleton|forelimb epipodium|anterior zeugopodium|forelimb epipodium skeleton|radius and ulna|fore epipodium skeleton The collection of all skeletal elements in an forelimb zeugopod region. UBERON:0010708 pectoral complex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010708 pectoral appendage/girdle complex|pectoral girdle plus anterior limb or fin|pectoral girdle plus pectoral limb or fin|upper limb|upper limb and pectoral girdle|upper limb and shoulder Appendage girdle complex that when present, encompasses the pectoral appendicular skeleton and the pectoral girdle. CHEBI:52320 ergosteryl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52320 UBERON:0010709 pelvic complex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010709 pelvic girdle plus pelvic limb or fin|pelvic appendage/girdle complex|lower limb|pelvic girdle plus posterior limb or fin|lower limb and pelvis|lower limb and pelvic girdle Appendage girdle complex that when present, encompasses the pelvic appendicular skeleton and the pelvic girdle. CHEBI:52322 zymosterol ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52322 UBERON:0010707 appendage girdle complex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010707 limb|girdle plus limb or fin|appendage/girdle complex|appendage-girdle complex|appendage complex An organism subdivision that includes both an appendage and its associated girdle region. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc). CHEBI:52323 1,2-dioleoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52323 GO:1990112 RQC complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990112 ribosome quality control complex|ribosome-bound quality control complex A multiprotein complex that forms a stable complex with large ribosomal subunits (60S in eukaryotes and 50S in prokaryotes) containing stalled polypeptides and triggers their degradation (ribosomal quality control). In budding yeast, this complex includes Cdc48p, Rkr1p, Tae2p, Rqc1p, Npl4p and Ufd1p proteins. GO:1990113 RNA polymerase I assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990113 RNA Polymerase I complex assembly|DNA-directed RNA polymerase I complex assembly The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase I complex. GO:1990114 RNA polymerase II core complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990114 DNA-directed RNA polymerase II, core complex assembly|RNA Polymerase II assembly The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase II core complex. GO:1990115 RNA polymerase III assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990115 RNA Polymerase III complex assembly|DNA-directed RNA polymerase III complex assembly The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase III complex. GO:1990110 callus formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990110 The process by which a callus is formed at a wound site. A plant callus is a portion of plant tissue that consists of mass of undifferentiated plant cells. It consists primarily of parenchyma cells but possibly contains other cell types as the callus begins to differentiate. GO:1990111 spermatoproteasome complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990111 A proteasome specifically found in mammalian testis. Contains the proteasome activator PA200 in the regulatory particle, and beta1i, beta2i, beta5i and/or alpha4s in the core (20S) subunit. Beta1i, beta2i and beta5i are inducible catalytic subunits, closely related to beta1, beta2 and beta5. Alpha4s is a sperm-specific 20S subunit, but unlike other alternative 20S subunits alpha4s lies in the outer alpha-ring and lacks catalytic activity. CHEBI:66961 cannabinerolate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66961 CHEBI:66962 cannabigerolate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66962 CHEBI:66963 Delta(9)-tetrahydrocannabinolate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66963 CHEBI:66964 Delta(9)-tetrahydrocannabinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66964 CHEBI:66960 olivetol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66960 GO:0015498 pantothenate:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015498 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: pantothenate(out) + Na+(out) = pantothenate(in) + Na+(in). GO:0015499 formate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015499 RHEA:29679 formate uptake transmembrane transporter activity|formate uptake permease activity Enables the transfer of formate from one side of a membrane to the other. Formate is also known as methanoate, the anion HCOO- derived from methanoic (formic) acid. GO:0015494 aromatic amino acid:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015494 aromatic amino acid:hydrogen symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: aromatic amino acid(out) + H+(out) = aromatic amino acid(in) + H+(in). GO:0015495 gamma-aminobutyric acid:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015495 Reactome:R-HSA-428625 GABA:hydrogen symporter activity|4-aminobutyrate:proton symporter activity|GABA:proton symporter activity|gamma-aminobutyric acid permease activity|4-aminobutanoate:hydrogen symporter activity|4-aminobutanoate:proton symporter activity|gamma-aminobutyric acid:hydrogen symporter activity|4-aminobutyrate:hydrogen symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: gamma-aminobutyric acid(out) + H+(out) = gamma-aminobutyric acid(in) + H+(in). GO:0015496 putrescine:ornithine antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015496 putrescine:hydrogen symporter activity|putrescine-ornithine antiporter activity|putrescine/ornithine antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: putrescine(out) + ornithine(in) = putrescine(in) + ornithine(out). GO:0015497 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015497 GO:1990116 ribosome-associated ubiquitin-dependent protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990116 ribosome-associated ubiquitin-dependent protein degradation|ribosome-associated ubiquitin-dependent protein breakdown|ribosome-associated degradation|ribosome-associated ubiquitin-dependent protein catabolism|RAD The chemical reactions and pathways resulting in the breakdown of a protein or peptide encoded by an aberrant message and associated with a stalled ribosome. Degradation is initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the ribosome-associated protein. GO:0015490 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015490 GO:0015491 cation:cation antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015491 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cation A(out) + cation B(in) = cation A(in) + cation B(out). GO:1990117 B cell receptor apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990117 B cell receptor extrinsic apoptotic signaling pathway|extrinsic apoptotic signaling pathway via BCR|extrinsic apoptotic signaling pathway via B cell antigen receptor An extrinsic apoptotic signaling pathway initiated by the cross-linking of an antigen receptor on a B cell. GO:1990118 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990118 GO:0015492 phenylalanine:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015492 phenylalanine:hydrogen symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phenylalanine(out) + H+(out) = phenylalanine(in) + H+(in). GO:0015493 lysine:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015493 lysine:hydrogen symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lysine(out) + H+(out) = lysine(in) + H+(in). GO:1990119 ATP-dependent RNA helicase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990119 Stops, prevents or reduces the activity of ATP-dependent RNA helicase. GO:1990123 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990123 GO:1990124 messenger ribonucleoprotein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990124 messenger ribonucleoprotein particle|mRNP|mRNP complex|mRNA-protein complex A ribonucleoprotein complex containing both protein and messenger RNA (mRNA) molecules. GO:1990125 DiaA complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990125 DiaA homotetramer A homotetrameric protein complex consisting of a symmetrical pair of DiaA homodimers. Facilitates DnaA binding to the origin of replication during replication initiation. GO:1990126 retrograde transport, endosome to plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990126 The directed movement of membrane-bounded vesicles from endosomes back to the plasma membrane, a trafficking pathway that promotes the recycling of internalized transmembrane proteins. GO:1990120 messenger ribonucleoprotein complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990120 messenger ribonucleoprotein assembly|mRNP assembly|mRNP complex assembly|mRNA-protein complex assembly The aggregation, arrangement and bonding together of proteins and messenger RNA (mRNA) molecules to form a messenger ribonucleoprotein (mRNP) complex. GO:1990121 H-NS complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990121 DNA-binding protein H-NS complex|histone-like protein H-NS complex A multimer of H-NS proteins that is involved in bacterial nucleoid condensation and negative regulation of global gene expression by directly binding to promoter regions. Recognizes both structural and sequence-specific motifs in double-stranded DNA and has binding preference for bent DNA. GO:1990122 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990122 GO:1990127 intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990127 A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of osmotic stress, and ends when the execution phase of apoptosis is triggered. GO:1990128 obsolete pre-primosome complex involved in replication initiation biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990128 pre-primosome complex involved in replication initiation OBSOLETE. A protein-DNA complex involved in replication initiation at the origin of replication. GO:1990129 obsolete pre-primosome complex involved in replication restart biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990129 pre-primosome complex involved in replication restart OBSOLETE. A protein-DNA complex involved in replication restart after a stalled replication fork has been repaired. GO:1990134 epithelial cell apoptotic process involved in palatal shelf morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990134 An apoptotic process in a palatal shelf epithelial cell that contributes to the shaping of the palatal shelf. CHEBI:76306 (+)-menthol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76306 GO:1990135 flavonoid sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990135 Catalysis of the reaction: a flavonoid + 3'-phosphoadenosine-5'-phosphosulfate = sulfated flavonoid + adenosine-3',5'-diphosphate. This reaction is the transfer of a sulfate group to the hydroxyl group of a flavonoid acceptor, producing the sulfated flavonoid derivative. CHEBI:76307 omega-hydroxy fatty acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76307 CHEBI:76304 22-hydroxydocosanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76304 GO:1990136 linoleate 9S-lipoxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990136 EC:1.13.11.58|RHEA:30291 9S-lipoxygenase activity|9-lipoxygenase activity|linoleate 9-lipoxygenase activity|linoleate:oxygen 9S-oxidoreductase activity Catalysis of the reaction: linoleate + O2 = (9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate. CHEBI:76305 26-hydroxyhexacosanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76305 GO:1990137 plant seed peroxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990137 EC:1.11.2.3|MetaCyc:RXN-11819 peroxygenase activity Catalysis of the reaction: R1H + R2OOH = R1OH + R2OH. GO:1990130 GATOR1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990130 IML1 complex|SEACIT complex A protein complex involved in regulation of non-nitrogen-starvation (NNS) autophagic process. In S. cerevisiae this complex contains Iml1p, Npr2p and Npr3p proteins. In humans the GATOR1 complex consists of DEPDC5, Nprl2, Nprl3. PO:0004703 carpel primordium biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0004703 心皮原基(可視的） (Japanese, exact)|portion of carpel primordium tissue (exact)|primordio de carpelo (Spanish, exact)|carpel primordia (exact, plural) A phyllome primordium (PO:0025128) that develops from a carpel anlagen (PO:0006005) and is committed to the development of a carpel (PO:0009030). GO:1990131 Gtr1-Gtr2 GTPase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990131 A heterodimer GTPase complex. In S. cerevisiae, this complex contains Gtr1p and Gtr2p proteins. PO:0004704 sepal primordium biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0004704 portion of sepal primordium tissue (exact)|がく片原基（可視的） (Japanese, exact)|sepal primordia (exact, plural)|primordio de sépalo (Spanish, exact) A phyllome primordium (PO:0025128) that develops from a sepal anlagen (PO:0025485) and is committed to the development of a sepal (PO:0009031). GO:1990132 obsolete release of misfolded protein from chaperone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990132 release of misfolded protein from chaperone OBSOLETE. The release of misfolded proteins that are being held by the chaperone heat shock protein (Hsp) and targeting them for destruction by the Ub-proteasome machinery. CHEBI:76308 tetradecanedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76308 GO:1990133 molybdopterin cofactor (Moco) biosynthesis adenylyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990133 A heterodimeric protein complex which adenylates two molecules of the sulfur carrier subunit of the molybdopterin (MPT) cofactor synthase using ATP as part of molybdopterin cofactor (Moco) biosynthesis. In E. coli the subunits are MoeB and MoaD; Moco biosynthesis and its constituent molecules are evolutionarily conserved. CHEBI:76309 omega-oxo fatty acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76309 PO:0004705 stamen primordium biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0004705 雄蕊原基（可視的） (Japanese, exact)|primordio de estambre (Spanish, exact)|stamen primordia (exact, plural)|portion of stamen primordium tissue (exact) A phyllome primordium (PO:0025128) that develops from a stamen anlagen (PO:0025486) and is committed to the development of a stamen (PO:0009029). CHEBI:66980 nootropic agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_66980 PO:0004709 axillary bud biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0004709 腋芽 (Japanese, exact)|yema axilar (Spanish, exact) A bud (PO:0000055) that develops from an axillary bud meristem (PO:0000232). CHEBI:66981 ophthalmology drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_66981 CHEBI:66982 mycophenolic acid O-acyl-glucuronide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66982 CHEBI:66987 radiation protective agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_66987 GO:0015476 hemaglutinin autotransporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015476 Enables the transfer of hemaglutinin from the periplasm to the external milieu; the hemaglutinin and the porin are the N- and C-terminal regions of the same protein, respectively. GO:0015477 obsolete receptor porin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015477 receptor porin activity OBSOLETE. A porin of the bacterial outer membrane that forms transmembrane pores and transports relatively large molecules from the external milieu to the periplasm in an energized process. Energizing of transport across the outer membrane requires a heterotrimeric complex of proteins, the TonB-ExbB-ExbD complex, or in some cases, the TolA-TolQ-TolR complex. Energizing requires proton motive force across the cytoplasmic membrane. GO:0015478 oligosaccharide transporting porin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015478 raffinose porin Enables the transfer of oligosaccharide, sized less than 1000 Da, from one side of a membrane to the other. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria. GO:0015479 obsolete outer membrane exporter porin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015479 outer membrane exporter porin OBSOLETE. (Was not defined before being made obsolete). GO:0015472 obsolete fimbrium-specific chaperone activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015472 fimbrium-specific chaperone activity OBSOLETE. Assists in the correct assembly of fimbria, extracellular organelles that are used to attach a bacterial cell to a surface, but is not a component of the fimbrium when performing its normal biological function. GO:0015473 fimbrial usher porin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015473 A porin that acts in the assembly of fimbria together with fimbrial chaperone. GO:0015474 autotransporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015474 Transports a passenger protein from the periplasm to the external milieu; the passenger protein and the porin are the N- and C-terminal regions of the same protein, respectively. GO:0015475 adhesin autotransporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015475 Enables the transfer of adhesin from the periplasm to the external milieu; the adhesin and the porin are the N- and C-terminal regions of the same protein, respectively. GO:1990138 neuron projection extension biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990138 neuron process extension|neuron protrusion extension|neuronal cell projection extension|neurite extension Long distance growth of a single neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite. GO:1990139 protein localization to nuclear periphery biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990139 A process in which a protein is transported to, or maintained in, a location within the nuclear periphery. GO:0015470 obsolete bacteriocin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015470 bacteriocin activity OBSOLETE. Polypeptide antibiotic secreted by bacteria and able to kill bacteria of susceptible strains after absorption by specific cell surface receptor. CHEBI:76301 inositol phosphate oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76301 GO:0015471 nucleoside-specific channel forming porin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015471 Enables the energy independent passage of nucleoside, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria. GO:1990145 maintenance of translational fidelity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990145 Suppression of the occurrence of translational errors, such as codon-anticodon mis-paring, during the process of translation of a protein using an mRNA template. CHEBI:76317 octanedioyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76317 GO:1990146 protein localization to rhabdomere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990146 A process in which a protein is transported to, or maintained in, a location within a rhabdomere. CHEBI:76318 22-oxodocosanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76318 GO:1990147 talin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990147 Interacting selectively and non-covalently with a talin, a family of related cytoskeletal proteins that play a role in assembly of actin filaments and migration of various cell types. CHEBI:76315 dodecanedioyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76315 CHEBI:76316 decanedioyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76316 GO:1990148 glutamate dehydrogenase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990148 glutamic acid dehydrogenase complex|dehydrogenase, glutamate (nicotinamide adenine dinucleotide (phosphate)) complex|L-glutamic acid dehydrogenase complex|NAD(P)H-dependent glutamate dehydrogenase complex|glutamic dehydrogenase complex|glutamate dehydrogenase (NADP+) complex|NAD(P)-glutamate dehydrogenase complex|L-glutamate:NADP+ oxidoreductase (deaminating) complex|L-glutamate dehydrogenase complex A homomeric protein complex that possesses glutamate dehydrogenase activity. This complex is evolutionarily conserved except that the number of homoprotomers per complex varies. GO:1990141 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990141 GO:1990142 envenomation resulting in hemolysis in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990142 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with hemolysis in the bitten organism. GO:1990143 CoA-synthesizing protein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990143 CoA-SPC|coenzyme A-synthesizing protein complex A multisubunit complex likely involved in the synthesis of coenzyme A (CoA). In S. cerevisiae, the complex consists of at least Cab2, Cab3, Cab4 and Cab5 but may also include Sis2 and Vhs3. The latter subunits are shared by the GO:0071513 phosphopantothenoylcysteine decarboxylase complex that catalyses the third step of the coenzyme A (CoA) biosynthetic pathway. CHEBI:76319 docosanedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76319 GO:1990144 intrinsic apoptotic signaling pathway in response to hypoxia biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990144 A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to hypoxia (lowered oxygen tension). Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. The pathway ends when the execution phase of apoptosis is triggered. GO:1990140 MPT synthase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990140 molybdopterin cofactor (Moco) biosynthesis sulfurtransferase complex A heterodimeric protein complex which catalyses sulfur transfer from the sulfur carrier subunit of MPT synthase to precursor Z to synthesize MPT as part of molybdopterin cofactor (Moco) biosynthesis. In E. coli the subunits are MoaE and MoaD; in human, MOCS2B and MOCS2A. Moco biosynthesis and its constituent molecules are evolutionarily conserved. CHEBI:66993 tocolytic agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_66993 GO:0015487 melibiose:cation symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015487 melibiose:monovalent cation symporter activity|melibiose permease activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: melibiose(out) + monovalent cation(out) = melibiose(in) + monovalent cation(in). CHEBI:66998 histidinate derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_66998 GO:0015488 glucuronide:cation symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015488 glucuronoside permease activity|glucuronide:monovalent cation symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucuronide(out) + monovalent cation(out) = glucuronide(in) + monovalent cation(in). GO:0015489 putrescine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015489 Enables the transfer of putrescine from one side of a membrane to the other. Putrescine is 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine. GO:0015483 long-chain fatty acid transporting porin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015483 TC:1.B.9.1.1 Enables the transfer of long-chain fatty acids from one side of a membrane to the other. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22. This transporter is a porin and so enables the energy independent passage of substances, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria. GO:0015484 obsolete hemolysin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015484 hemolysin activity OBSOLETE. Any substance that causes the lysis of red blood cells. GO:0015485 cholesterol binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015485 Interacting selectively and non-covalently with cholesterol (cholest-5-en-3-beta-ol); the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. GO:0015486 glycoside-pentoside-hexuronide:cation symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015486 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: (glycoside, pentoside or hexuronide)(out) + monovalent cation(out) = (glycoside, pentoside or hexuronide)(in) + monovalent cation(in). The cation is Na+, Li+ or H+. GO:1990149 obsolete COPI vesicle coating biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990149 COPI vesicle coating OBSOLETE. The addition of COPI proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat. GO:0015480 obsolete secretin (sensu Bacteria) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015480 secretin (sensu Bacteria) OBSOLETE. Secretins are Gram-negative bacterial outer membrane proteins that form multimeric pores through which macromolecules, usually proteins, can pass. Form homomultimeric ring structures, 10-20 subunits per complex, with large central pores (inner diameters of 5-10 nm). CHEBI:76314 trans-2-nonenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76314 CHEBI:76311 26-oxohexacosanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76311 GO:0015481 maltose transporting porin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015481 Wikipedia:Maltoporin maltoporin Enables the transfer of maltose from one side of a membrane to the other. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the enzymatic breakdown of glycogen and starch. This transporter is a porin so enables the energy independent passage of substances, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria. GO:0015482 obsolete voltage-gated anion channel porin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015482 voltage-dependent anion channel porin activity|voltage-gated anion channel porin activity OBSOLETE. This term was not defined before being made obsolete. CHEBI:76312 hexacosanedioate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76312 CHEBI:76328 omega-oxo fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76328 CHEBI:76327 adipoyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76327 GO:0015458 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015458 GO:0015459 potassium channel regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015459 potassium channel gating activity Modulates potassium channel activity via direct interaction interaction with a potassium channel (binding or modification). GO:0015454 light-driven active transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015454 TC:3.E light-driven pumps|Light absorption-driven transporters Primary active transport of a solute across a membrane, driven by light. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source. GO:0015455 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015455 GO:0015456 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015456 GO:0015457 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015457 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015450 Reactome:R-HSA-1222523|EC:7.4.2.4|EC:7.4.2.3 protein translocase activity Primary active carrier-mediated transport of a protein across a membrane, driven by the hydrolysis of the diphosphate bond of inorganic pyrophosphate, ATP, or another nucleoside triphosphate. The transport protein may or may not be transiently phosphorylated, but the substrate is not phosphorylated. GO:0015451 decarboxylation-driven active transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015451 TC:3.B|EC:7.2.4.5|EC:7.2.4.4|EC:7.2.4.3|EC:7.2.4.2|EC:7.2.4.1 decarboxylation-driven transporter Primary active transport of a solute across a membrane driven by decarboxylation of a cytoplasmic substrate. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source. GO:0015452 methyl transfer-driven active transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015452 TC:3.C Methyltransfer-driven transporters Primary active transport of a solute across a membrane driven by a methyl transfer reaction. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source. GO:0015453 oxidoreduction-driven active transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015453 TC:3.D Oxidoreduction-driven transporters Primary active transport of a solute across a membrane, driven by exothermic flow of electrons from a reduced substrate to an oxidized substrate. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source. CHEBI:76325 26-hydroxyhexacosanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76325 CHEBI:76322 22-hydroxydocosanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76322 CHEBI:134582 (4S)-4,16-dihydroxyretinoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134582 CHEBI:76339 dodecanedioyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76339 GO:0015469 obsolete channel-forming toxin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015469 channel-forming toxin activity OBSOLETE. A toxin that exerts its effects by forming a channel in a membrane that allows the unregulated passage of substances into and out of the cell. GO:0015465 obsolete lysin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015465 lysin activity OBSOLETE. An agent that can lyse cells. GO:0015466 obsolete autolysin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015466 autolysin activity OBSOLETE. An agent that can lyse the cell in which it is synthesized. GO:0015467 G-protein activated inward rectifier potassium channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015467 Reactome:R-HSA-1013020 G protein enhanced inward rectifier potassium channel activity|G-protein-enhanced inward rectifier potassium channel activity|G-protein-activated inward rectifier potassium channel activity|G protein activated inward rectifier potassium channel activity|G-protein enhanced inward rectifier potassium channel activity Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel, where the inward rectification is due to a voltage-dependent block of the channel pore by a G protein. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force. GO:0015468 obsolete colicin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015468 colicin OBSOLETE. Plasmid-encoded bacteriocins which are produced by enteric bacteria. Exert a lethal effect on other bacteria including E. coli strains that lack the Col plasmid. Bind to a cell surface receptor and are transported into the periplasm via an energy-dependent process involving a TonB- or TolA-dependent hetero-oligomeric protein complex. Some colicins kill their target cell by inserting into the cytoplasmic membrane where they form voltage-sensitive (trans-negative) channels that depolarize and deenergize the cell, and thereby kill it. GO:0015461 obsolete endosomal oligosaccharide transporter biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015461 endosomal oligosaccharide transporter OBSOLETE. (Was not defined before being made obsolete). GO:0015462 ABC-type protein transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015462 EC:7.4.2.5 ATPase-coupled protein transmembrane transporter activity|pilin/fimbrilin exporter activity|protein-transmembrane transporting ATPase activity|protein ABC transporter|ABC-type protein transmembrane transporter activity|protein-transporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein(out) = ADP + phosphate + protein(in). CHEBI:76332 26-oxohexacosanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76332 GO:0015463 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015463 GO:0015464 acetylcholine receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015464 Combining with acetylcholine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. CHEBI:76330 trans-2-octenedioyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76330 CHEBI:76335 3-oxooctanedioyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76335 CHEBI:76333 (S)-3-hydroxyoctanedioyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76333 CHEBI:76334 hexacosanedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76334 GO:0015460 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015460 CHEBI:76348 (S)-3-hydroxydecanedioyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76348 CHEBI:76349 3-oxodecanedioyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76349 GO:0015436 ABC-type capsular-polysaccharide transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015436 MetaCyc:3.6.3.38-RXN|EC:7.6.2.12 ATP phosphohydrolase (capsular-polysaccharide-exporting)|ATP-dependent capsular-polysaccharide transporter activity|ATPase-coupled capsular-polysaccharide transporter activity|capsular-polysaccharide-transporting ATPase activity|capsular-polysaccharide ABC transporter Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + capsular polysaccharide(in) = ADP + phosphate + capsular polysaccharide(out). GO:0015437 lipopolysaccharide floppase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015437 ATPase-coupled intramembrane lipopolysaccharide transporter activity|lipopolysaccharide-transporting ATPase activity|ATP-dependent intramembrane lipopolysaccharide transporter activity|LPS-transporting ATPase activity|lipopolysaccharide floppase activity (cytosolic to exoplasmic leaftlet) Enables the transfer of a lipopolysaccharide from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP. GO:0015438 ABC-type teichoic acid transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015438 MetaCyc:3.6.3.40-RXN|EC:7.5.2.4 teichoic-acid-transporting ATPase activity|teichoic acid transmembrane transporter activity|ABC-type teichoic-acid transporter|ATPase-coupled teichoic acid transmembrane transporter activity|ATP-dependent teichoic acid transmembrane transporter activity|teichoic-acid ABC transporter Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + teichoic acid(in) = ADP + phosphate + teichoic acid(out). GO:0015439 ABC-type heme transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015439 MetaCyc:TRANS-RXN0-162|RHEA:19261|MetaCyc:3.6.3.41-RXN|Reactome:R-HSA-382560|EC:7.6.2.5|Reactome:R-HSA-1369065|Reactome:R-HSA-917979|Reactome:R-HSA-5683355 protoheme IX ABC transporter activity|haem-transporting ATPase activity|ATP-dependent heme transmembrane transporter activity|heme ABC transporter|ATPase-coupled heme transmembrane transporter activity|ATPase-coupled heme transporter activity|heme-transporting ATPase activity Catalysis of the reaction: ATP + H2O + heme(in) = ADP + phosphate + heme(out). GO:0015432 ABC-type bile acid transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015432 Reactome:R-HSA-193362|Reactome:R-HSA-5678517|RHEA:50048|Reactome:R-HSA-194153|TC:3.A.1.207.2 bile acid porter activity|bile acid-exporting ATPase activity|ATPase-coupled bile acid transmembrane transporter activity|ATP-dependent bile acid transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: bile acid(in) + ATP + H2O -> bile acid(out) + ADP + phosphate. GO:0015433 ABC-type peptide antigen transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015433 Reactome:R-HSA-983144|Reactome:R-HSA-1236949|TC:3.A.1.209.1 peptide antigen-transporting ATPase activity|major histocompatibility peptide transporter activity|peptide antigen ABC transporter|ATP-dependent peptide antigen transmembrane transporter activity|peptide antigen transporter activity|ATPase-coupled peptide antigen transmembrane transporter activity Catalysis of the reaction: peptide antigen(in) + ATP = peptide antigen(out) + ADP + phosphate. GO:0015434 ABC-type cadmium transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015434 MetaCyc:3.6.3.46-RXN|EC:7.2.2.2 ATPase-coupled cadmium transmembrane transporter activity|cadmium ABC transporter|ATP-dependent cadmium transmembrane transporter activity|cadmium-transporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cd (cytosol) = ADP + phosphate + Cd (vacuole). CHEBI:134567 diacylglycerol (18:1/0:0/18:1) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134567 GO:0015435 obsolete ABC-type efflux permease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015435 ABC-type efflux permease activity OBSOLETE. (Was not defined before being made obsolete). CHEBI:76342 (S)-3-hydroxydodecanedioyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76342 PR:000004716 brain-derived neurotrophic factor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000004716 BDNF|abrineurin A neurotrophin that is a translation product of the human BDNF gene or a 1:1 ortholog thereof. GO:0015430 ABC-type glycerol-3-phosphate transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015430 MetaCyc:3.6.3.20-RXN|RHEA:21669|EC:7.6.2.10 ATP-dependent glycerol-2-phosphate transmembrane transporter activity|ATPase-coupled glycerol-2-phosphate transmembrane transporter activity|ABC-type glycerol 3-phosphate transporter|glycerol-2-phosphate-transporting ATPase activity|ATPase-coupled glycerol-3-phosphate transmembrane transporter activity|glycerol-3-phosphate ABC transporter|glycerol-phosphate porter activity|glycerol-3-phosphate-transporting ATPase|glycerol phosphate-importing ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + glycerol-3-phosphate(out) = ADP + phosphate + glycerol-3-phosphate(in). CHEBI:76340 trans-2-dodecenedioyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76340 GO:0015431 ABC-type glutathione S-conjugate transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015431 RHEA:19121|EC:7.6.2.3 ATPase-coupled glutathione S-conjugate transmembrane transporter activity|conjugate transporter activity|glutathione S-conjugate-transporting ATPase activity|GS-X pump|ATP-dependent glutathione S-conjugate export pump|glutathione S-conjugate-exporting ATPase activity|MRP1/GS-X pump Catalysis of the reaction: ATP + H2O + glutathione S-conjugate(in) -> ADP + phosphate + glutathione S-conjugate(out). CHEBI:76346 3-oxododecanedioyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76346 CHEBI:76347 trans-2-decenedioyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76347 CHEBI:76345 decanedioyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76345 GO:1990101 DnaA-oriC complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990101 DnaA-DNA complex A protein-DNA complex containing the initiator protein DnaA bound to high-affinity recognition sites in the unique origin of replication, oriC. DnaA-oriC binding is the first step in assembly of a bacterial pre-replicative complex (pre-RC) and is responsible for the timely initiation of replication once per cell cycle. GO:1990102 DnaA-DiaA complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990102 DnaA-DiaA-DNA complex A protein-DNA complex containing a tetramer of DiaA attached to multiple DnaA molecule bound to oriC DNA. Regulates timely initiation of chromosomal replication during the cell cycle by stimulating assembly of DnaA-oriC complexes, conformational changes in ATP-DnaA initiation complexes, and unwinding of oriC duplex DNA. GO:1990103 DnaA-HU complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990103 DnaA-HU-DNA complex A protein-DNA complex containing DNA-bound DnaA attached to HU. HU is a dimer encoded by two closely related genes. Essential for the initiation of replication in bacteria; stimulates the DnaA-dependent unwinding of oriC. GO:1990104 DNA bending complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990104 histone-like DNA binding complex A protein-DNA complex that contains DNA in combination with a protein which binds to and bends DNA. Often plays a role in DNA compaction. GO:1990100 DnaB-DnaC complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990100 DnaB6-DnaC6 complex|DnaB6-DnaC3 complex|helicase-loading complex A protein complex containing homohexameric DNA helicase DnaB, and the DNA helicase loader DnaC. The helicase loader DnaC delivers DnaB to the chromosomal origin (oriC). GO:0015447 obsolete type II protein secretor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015447 type II protein secretor activity OBSOLETE. This term was not defined before being made obsolete. GO:0015448 obsolete type III protein (virulence-related) secretor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015448 type III protein (virulence-related) secretor activity OBSOLETE. This term was not defined before being made obsolete. GO:0015449 obsolete type IV protein (DNA-protein) secretor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015449 type IV protein (DNA-protein) secretor activity OBSOLETE. This term was not defined before being made obsolete. CHEBI:134574 alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(38:2) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134574 GO:0015443 obsolete sodium-transporting two-sector ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015443 sodium-transporting two-sector ATPase activity OBSOLETE. Catalysis of the reaction: ATP + H2O + Na+(in) = ADP + phosphate + Na+(out). GO:0015444 magnesium transmembrane transporter activity, phosphorylative mechanism biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015444 EC:7.2.2.14|MetaCyc:3.6.3.2-RXN|RHEA:10260 magnesium importing ATPase activity|magnesium-translocating P-type ATPase activity|Mg(2+)-importing ATPase activity|ATP phosphohydrolase (Mg2+-importing)|Mg2+-importing ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Mg2+(out) -> ADP + phosphate + Mg2+(in). GO:0015445 P-type silver transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015445 EC:7.2.2.15|RHEA:14733|MetaCyc:3.6.3.53-RXN silver exporting ATPase activity|silver transmembrane transporter activity, phosphorylative mechanism|ATP phosphohydrolase (Ag+-exporting)|silver-exporting ATPase activity|Ag+-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ag+(in) -> ADP + phosphate + Ag+(out). GO:0015446 ATPase-coupled arsenite transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015446 RHEA:11348|EC:7.3.2.7|TC:3.A.4.1.1|MetaCyc:3.6.3.16-RXN arsenite-transporting ATPase activity|arsenite-translocating ATPase activity|arsenite-transmembrane transporting ATPase activity|arsenite ABC transporter|arsenical pump-driving ATPase activity|arsenite transporting ATPase activity|arsenical resistance efflux pump|arsenical resistance ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + arsenite(in) = ADP + phosphate + arsenite(out). GO:1990109 rejection of pollen from other species biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990109 unilateral interspecific incompatibility The process involved in the rejection of pollen of one species by cells in the stigma of another species. GO:0015440 ABC-type peptide transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015440 RHEA:14429|EC:7.4.2.5|MetaCyc:3.6.3.43-RXN peptide-transporting ATPase activity|peptide ABC transporter|ATPase-coupled peptide transmembrane transporter activity|ATP-dependent peptide transmembrane transporter activity Catalysis of the reaction: ATP + H2O + peptide(in) = ADP + phosphate + peptide(out). Peptides exported include alpha-hemolysin, cyclolysin, colicin V and siderophores from Gram-negative bacteria, and bacteriocin, subtilin, competence factor and pediocin from Gram-positive bacteria. GO:0015441 ABC-type beta-glucan transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015441 EC:7.5.2.3|RHEA:18453|MetaCyc:3.6.3.42-RXN ATPase-coupled beta-glucan transporter activity|ATP-dependent beta-glucan transporter activity|beta-glucan-transporting ATPase activity|ABC-type beta-glucan transporter|beta-glucan ABC transporter Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + beta-glucan(in) = ADP + phosphate + beta-glucan(out). CHEBI:76352 octanedioyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76352 GO:0015442 obsolete hydrogen-/sodium-translocating ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015442 proton-/sodium-translocating ATPase activity|hydrogen-/sodium-translocating ATPase activity OBSOLETE. Catalysis of the reaction: ATP + H2O + (Na+ or H+)(in) = ADP + phosphate + (Na+ or H+)(out). GO:1990105 obsolete regulation of voltage-gated potassium channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990105 regulation of voltage-gated potassium channel activity OBSOLETE. Any process that modulates the frequency, rate or extent of voltage-gated potassium channel activity. CHEBI:134572 alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(34:1) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134572 GO:1990106 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990106 GO:1990107 thiazole synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990107 RHEA:26297 1-deoxy-D-xylulose 5-phosphate:thiol sulfurtransferase activity Catalysis of the reaction: 1-deoxy-D-xylulose 5-phosphate + 2-iminoacetate + thiocarboxy-adenylate-[sulfur-carrier protein ThiS] = 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + [sulfur-carrier protein ThiS] + 2 H2O. GO:1990108 protein linear deubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990108 A protein deubiquitination process in which a linear polymer of ubiquitin, formed by the amino-terminal methionine (M1) of one ubiquitin molecule and by the carboxy-terminal glycine (G76) of the next, is removed from a protein. CHEBI:76356 (3S,6Z,9Z,12Z,15Z,18Z,21Z)-3-hydroxytetracosahexaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76356 UBERON:0019196 iliac artery endothelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0019196 CHEBI:17947 3-dehydroquinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17947 CHEBI:17948 (+)-taxifolin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17948 CHEBI:17945 N-cyclohexylformamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17945 CHEBI:17943 (S)-2-O-sulfolactic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17943 CHEBI:17941 diisopropyl fluorophosphate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17941 CHEBI:17942 D-allose 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17942 UBERON:0019190 mucous gland of lung biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0019190 peribronchial gland|bronchial mucous gland|bronchial gland UBERON:0019189 carotid artery endothelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0019189 carotid epithelium|carotid endothelium CHEBI:17938 5alpha-ergosta-7,22-diene-3beta,5-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17938 CHEBI:17939 puromycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17939 CHEBI:17936 2-acyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17936 CHEBI:17937 L-rhamnono-1,4-lactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17937 CHEBI:17934 pregnan-21-al biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17934 CHEBI:17935 octanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17935 CHEBI:17933 calcidiol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17933 CHEBI:17931 N-hydroxy-2-acetamidofluorene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17931 CHEBI:42905 alpha-L-galactose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_42905 CHEBI:17969 sedoheptulose 1,7-bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17969 CHEBI:66904 2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_66904 CHEBI:17967 urethane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17967 CHEBI:66905 aureusidin 6-O-beta-glucoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66905 CHEBI:17968 butyrate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17968 CHEBI:66906 2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_66906 CHEBI:17965 isoorientin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17965 CHEBI:17966 cyclohexyl isocyanide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17966 CHEBI:17964 pipecolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17964 CHEBI:17961 farnesyl triphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17961 CHEBI:17962 CDP-diacylglycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17962 CHEBI:17960 3-oxopropanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17960 CHEBI:66907 bracteatin 6-O-beta-glucoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66907 CHEBI:66909 alpha-D-Glcp-(1->3)-L-Rhap biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66909 CHEBI:66914 UDP-alpha-D-galactose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66914 CHEBI:17958 alkyl cinnamate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17958 CHEBI:66915 UDP-alpha-D-galactofuranose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66915 CHEBI:17959 oxidized Renilla luciferin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17959 CHEBI:66916 alanine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66916 CHEBI:17957 5-(2-hydroxyethyl)-4-methylthiazole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17957 CHEBI:17954 1-alpha-D-galactosyl-sn-glycerol 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17954 CHEBI:17955 2'-deoxyribonucleoside diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17955 CHEBI:66911 alpha-D-mannosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-beta-D-galactosyl-1-diphosphodecaprenol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66911 CHEBI:17952 flavonol 3-O-[alpha-L-rhamnosyl-(1->6)-beta-D-glucoside]s biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17952 CHEBI:66912 alpha-D-abequosyl-(1->3)-alpha-D-mannosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-beta-D-galactosyl-1-diphosphodecaprenol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66912 CHEBI:17953 xanthopterin-B2 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17953 CHEBI:17950 beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-N-acylsphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17950 CHEBI:66918 ergosta-5,7-dien-3beta-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66918 CHEBI:17907 styrene oxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17907 CHEBI:17905 coenzyme M biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17905 CHEBI:17906 aminoacetone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17906 CHEBI:17903 4-(dimethylamino)azobenzene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17903 CHEBI:17901 6-O-acetyl-D-glucose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17901 CHEBI:17902 N-carbamoylputrescine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17902 CHEBI:66922 citrullinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_66922 UBERON_CORE:protects protects biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/uberon/core#protects protects CHEBI:66924 creatinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_66924 CHEBI:66929 trans,octacis-decaprenylphospho-beta-D-ribofuranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_66929 CHEBI:66936 (2Z,4E)-2-hydroxy-6-oxonona-2,4-dienedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_66936 CHEBI:66937 trans,octacis-decaprenylphospho-beta-D-ribofuranose 5-phosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66937 CHEBI:66938 keto-D-gluconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_66938 CHEBI:66939 (2Z,4E,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_66939 CHEBI:66933 N-alkylglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_66933 CHEBI:66934 cyanoamino acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_66934 CHEBI:6104 kanamycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_6104 CHEBI:66940 fructosylglycinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_66940 CHEBI:66941 ecgononium methyl ester(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66941 CHEBI:66942 4-oxo-4-(pyridin-3-yl)butanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66942 CHEBI:17929 N(omega),N(omega)-dimethyl-L-arginine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17929 CHEBI:17927 N(1)-acetylspermidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17927 CHEBI:17928 1-amino-1-deoxy-scyllo-inositol 4-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17928 CHEBI:66947 (2E,4Z)-4-hydroxy-6-oxohexa-2,4-dienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66947 CHEBI:17925 alpha-D-glucose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17925 CHEBI:66948 isoglutamate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66948 CHEBI:17926 hydrogenobyrinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17926 CHEBI:66949 nucleoside 3'-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66949 CHEBI:17924 D-glucitol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17924 CHEBI:17922 fluoren-9-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17922 CHEBI:66944 2,6-dihydroxypseudooxynicotinium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66944 CHEBI:66945 4-nitro-6-oxohepta-2,4-dienedioate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66945 CHEBI:17920 3-methyleneoxindole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17920 CHEBI:66946 4-(6-hydroxypyridin-3-yl)-4-oxobutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_66946 CHEBI:66950 olivetolate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66950 CHEBI:66951 4-oxo-4-(pyridin-3-yl)butanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_66951 CHEBI:66952 homocysteinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_66952 CHEBI:66953 5-oxo-1,2-campholide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66953 CHEBI:17919 3-mercapto-2-mercaptomethylpropanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17919 CHEBI:17917 L-allysine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17917 CHEBI:66958 4-hydroxy-6-pentylpyran-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66958 CHEBI:17915 hexano-6-lactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17915 GO:0039599 cleavage by virus of host mRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039599 viral endoribonuclease activity involved in degradation of host mRNA|host mRNA cleavage by viral endoribonuclease Any process in which a host pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner by a viral endoribonuclease. CHEBI:17913 streptidine 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17913 CHEBI:66954 2',3'-cyclic nucleotide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66954 CHEBI:66955 olivetolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_66955 CHEBI:66956 antidyskinesia agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_66956 CHEBI:66957 3,5,7-trioxododecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66957 GO:0039593 suppression by virus of host exit from mitosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039593 VZ:877 inhibition of host mitotic exit by virus Any viral process which decreases the rate or extent of a host cell leaving M phase of the cell cycle. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place. GO:0039594 endoribonuclease activity involved in viral induction of host mRNA catabolic process biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0039594 Any endoribonuclease activity that contributes to the viral-induced catabolism of host mRNA. GO:0039591 suppression by virus of host tapasin activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039591 VZ:818 inhibition of host TAPBP by virus|inhibition of host tapasin by virus|suppression by virus of host TAP binding protein Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host tapasin (TAP binding protein/TAPBP) activity. Tapasin is a type I transmembrane protein essential for the optimal expression of stable MHC class I molecules on the host cell surface. By inhibiting host tapasin activity, viruses can prevent presentation of their antigens at the cell surface, and thereby evade the host anti-viral immune response. GO:0039592 suppression by virus of G2/M transition of host mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039592 VZ:876 host G2/M cell cycle arrest by virus Any viral process that decreases the rate or extent of progression from G2 phase to M phase of the host mitotic cell cycle. GO:0039597 induction by virus of host endoribonuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039597 viral induction of host RNAse activity Any viral process that activates or increases the frequency, rate or extent of host endoribonuclease activity. GO:0039598 obsolete induction by virus of host nuclear polyadenylation-dependent mRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039598 induction by virus of host nuclear poly(A)-dependent mRNA catabolic process|virus-mediated host mRNA decay by hyperadenylation|induction by virus of host nuclear polyadenylation-dependent mRNA catabolic process OBSOLETE. The process in which a virus increases the frequency, rate or extent of the breakdown of host messenger RNA (mRNA) initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA. GO:0039595 induction by virus of catabolism of host mRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039595 VZ:901 promotion of host mRNA degradation|viral induction of host mRNA decay|virus-mediated mRNA decay|induction by virus of host mRNA catabolic process|induction of host mRNA decay The process in which a virus increases the frequency, rate or extent of the breakdown of host messenger RNA (mRNA). GO:0039596 modulation by virus of host protein dephosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039596 Any viral process that modulates the frequency, rate or extent of dephosphorylation of a host protein. CHEBI:52317 thalianol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52317 CL:0000402 CNS interneuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000402 CHEBI:27353 xylulose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27353 CHEBI:27354 xylulose 5-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27354 CL:0000404 electrically signaling cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000404 A cell that initiates an electrical signal and passes that signal to another cell. CHEBI:27355 xylulose phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27355 CHEBI:27350 xyloside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27350 CL:0000408 male gamete biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000408 CHEBI:27351 xylosylgalactoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27351 CHEBI:6151 (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_6151 CHEBI:52303 sterol methyltransferase inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52303 CHEBI:27369 zwitterion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27369 CL:0000413 haploid cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000413 A cell whose nucleus contains a single haploid genome. CHEBI:27364 zinc molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27364 CHEBI:27365 zinc ion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27365 CL:0000417 endopolyploid cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000417 UBERON:0034763 hindbrain commissure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034763 Any commissure within the hindbrain. CHEBI:27362 zeta-carotene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27362 CHEBI:27363 zinc atom biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27363 CHEBI:42989 7beta-hydroxycholesterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_42989 CL:0000412 polyploid cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000412 A cell whose nucleus, or nuclei, each contain more than two haploid genomes. CHEBI:27338 xylene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27338 UBERON:0009777 intermediate reticular nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009777 A nucleus of brain that is part of a intermediate reticular formation. UBERON:0010755 secondary follicle corona biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010755 B cell corona|peripheral zone of follicle|mantle zone|inactive zone of follicle|dark zone of follicle The part of the secondary follicle that surrounds the germinal center. UBERON:0009778 pleural sac biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009778 A serous sac that has the pleura and the pleural cavity as parts. UBERON:0034768 morphological feature biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034768 A part of an organism or organ that is continuous with its surroundings and distinguished from its surroundings based on morphology. UBERON:0010753 lymph node secondary follicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010753 A secondary follicle that is located in a lymph node UBERON:0010754 germinal center biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010754 reaction center of follicle|nodule|lymhpoid nodule|central zone of follice|light zone of follicle A collection of activated B cells at the center of a secondary follicle, formed after B cells become activated and migrate to the center. UBERON:0034769 lymphomyeloid tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034769 CHEBI:42977 25-hydroxycholesterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_42977 UBERON:0010758 subdivision of organism along appendicular axis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010758 appendage segment|appendicular segment A major subdivision of an organism that divides an organism along an axis perpedicular to the main body anterior-posterior axis. In vertebrates, this is typically a fin or limb segment. In insects, this includes segments of appendages such as antennae, as well as segments of the insect leg. UBERON:0009773 renal tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009773 renal tubule (generic)|tubule of excretory system A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis. UBERON:0009775 lateral medullary reticular complex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009775 nuclei laterales myelencephali|lateral medullary reticular group|lateral group of medullary reticular formation|lateral reticular formation of the medulla oblongata A nuclear complex of the medullary reticular formation that can be divided into three subnuclei: the parvocellular, magnocellular and the subtrigeminal[WP,modified]. UBERON:0009776 intermediate reticular formation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009776 intermediate reticular formations . CHEBI:27346 xylonates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27346 CHEBI:27347 xylonolactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27347 CHEBI:27349 xylose phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27349 CHEBI:27343 xylogalacturonan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27343 CHEBI:27345 xylonate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27345 CHEBI:27341 xylitol phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27341 UBERON:0009767 proximal interphalangeal joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009767 PIP joint|PIJ joint An inter-phalangeal joint that connects a proximal phalanx to either a medial or distal phalanx. UBERON:0009768 distal interphalangeal joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009768 DIP joint|DIJ joint An inter-phalangeal joint that connects a distal phalanx to either a medial or proximal phalanx. UBERON:0010742 bone of pelvic complex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010742 hindlimb bone A bone that is part of a pelvic complex. Examples: pubis, ischium, fot phalanx, any tarsal bone, any bone of the pelvic fin or girdle. UBERON:0010743 meningeal cluster biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010743 cluster of meninges|meninges|cerebral meninges The collection of all meningeal layers that line a central nervous system. UBERON:0010748 lymph node follicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010748 follicle of lymph node A lymphoid follicle that is part of a lymph node. CHEBI:6121 ketamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_6121 CHEBI:27314 water-soluble vitamin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27314 CHEBI:27311 volatile oil component biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27311 UBERON:0034710 spinal cord ventricular layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034710 spinal cord lateral wall ventricular layer CHEBI:17989 daphnin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17989 CHEBI:17987 benzyl alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17987 UBERON:0034705 developing neuroepithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034705 neuroepithelium|embryonic neuroepithelium|neurepithelium An embryonic or larval epithelium that is committed to form part of the nervous system. UBERON:0034706 proliferating neuroepithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034706 An epithelium that is undergoing proliferation to provide large numbers of neuronal cells. CHEBI:17985 adenosine 3',5'-bismonophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17985 UBERON:0034707 differentiating neuroepithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034707 A neuroepithelium some of whose cells are undergoing terminal differentiation to become neuronal cells. UBERON:0034708 cerebellum marginal layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034708 marginal zone of cerebellum|MZCB CHEBI:17983 UDP-L-arabinose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17983 UBERON:0034709 hindbrain marginal layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034709 marginal zone of hindbrain|MZH CHEBI:17984 acyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17984 CHEBI:17981 O-acetyl-L-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17981 CHEBI:17982 6-acetamido-3-oxohexanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17982 CHEBI:17980 3'-phospho-5'-adenylyl sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17980 CHEBI:6178 L-arabinofuranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_6178 CHEBI:27329 xanthosine phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27329 UBERON:0019143 intramuscular adipose tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0019143 intramuscular fat Adipose tissue which is located throughout skeletal muscle and is responsible for the marbling seen in certain cuts of beef. In humans, excess accumulation of intramuscular fat is associated with insulin resistance and type 2 diabetes. CHEBI:27325 xanthophyll biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27325 CHEBI:27323 xanthommatins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27323 UBERON:0034720 head taste bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034720 A taste bud that is located on the skin of the head. UBERON:0034721 pharyngeal taste bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034721 A taste bud that is located in the pharynx. UBERON:0034711 cortical preplate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034711 The layer of the developing cerebral cortex that is formed from the first cohort of neurons to migrate out of the cortical ventricular zone; split by the second wave into marginal zone and subplate. UBERON:0034713 cranial neuron projection bundle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034713 neuron projection bundle from brain|cranial nerve or tract|cranial nerve fiber bundle|cranial nerve fiber tract Any of the cranial nerves, or their central nervous system analogs (the optic tract, the epiphyseal tract). These analogs are not true nerves, and are instead evaginated sensory afferents emanating from the brain CHEBI:17978 5-hydroxy-6-methylpyridine-3,4-dicarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17978 UBERON:0034714 epiphyseal tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034714 epiphyseal nerve A cranial nerve fiber tract that innervates the parietal eye. CHEBI:17979 aldehydo-L-xylose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17979 CHEBI:17976 ubiquinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17976 UBERON:0034715 pineal tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034715 pineal nerve A cranial nerve fiber tract that innervates the pineal body. CHEBI:17977 1,4-benzosemiquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17977 UBERON:0034717 integumental taste bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034717 A taste bud that is located external to the digestive tube, on the head or body, as found in species such as goldfish. CHEBI:17975 5,10-(methanylylidene)tetrahydromethanopterin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17975 UBERON:0034719 lip taste bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034719 A taste bud that is located on a lip. CHEBI:17972 ribonucleoside triphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17972 CHEBI:17973 alpha-D-galactose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17973 CHEBI:17970 N-acyl-D-mannosaminolactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17970 UBERON:0034730 olfactory tract linking bulb to ipsilateral dorsal telencephalon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034730 lateral olfactory tract|tractus olfactorius lateralis UBERON:0034722 mouth roof taste bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034722 A taste bud that is located on the roof of the mouth. UBERON:0034723 fin taste bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034723 A taste bud that is located on a fin. UBERON:0034724 esophageal taste bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034724 A taste bud that is located in the esophagus. UBERON:0034726 trunk taste bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034726 A taste bud that is located on the skin of the trunk. UBERON:0034728 autonomic nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034728 visceral nerve|nervus visceralis The autonomic nerve is a small nerve which carries postganglionic sympathetic and parasympathetic neurons from the zygomaticotemporal nerve; a branch of the maxillary nerve, to the lacrimal nerve; a branch of the ophthalmic nerve. These neurons derive from the superior cervical ganglion and the pterygopalatine ganglion respectively. They will travel to the lacrimal gland via the lacrimal nerve. Parasympathetic will induce lacrimation and vice versa. UBERON:0034729 sympathetic nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0034729 CHEBI:42939 cyclohexylammonium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_42939 CHEBI:27306 vitamin B6 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27306 NCBITaxon:5658 Leishmania organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_5658 Leishmania NCBITaxon:5653 Kinetoplastea organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_5653 kinetoplastids|kinetoplasts|Protomonadida|Kinetoplastida NCBITaxon:5654 Trypanosomatidae organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_5654 CHEBI:27300 vitamin D biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27300 CHEBI:17998 4-methylpentanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17998 CHEBI:17996 chloride biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17996 CHEBI:17997 dinitrogen biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17997 CHEBI:17994 D-ribose 1,5-bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17994 CHEBI:17992 sucrose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17992 CHEBI:17993 3-(3,4-dihydroxypyridinium-1-yl)-L-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17993 CHEBI:17990 1-O-(indol-3-ylacetyl)-beta-D-glucose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17990 GO:1990079 cartilage homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990079 negative regulation of cartilage homeostasis|regulation of cartilage homeostasis|positive regulation of cartilage homeostasis A tissue homeostatic process involved in the maintenance of an internal equilibrium within cartilage, including control of cellular proliferation and death and control of metabolic function. GO:1990075 periciliary membrane compartment biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990075 PCMC A plasma membrane region adjacent to the base of eukaryotic cilia and flagella that is enriched in endocytosis-associated proteins and vesicles and that appears to regulate ciliary membrane homeostasis. GO:1990076 cell wall polysaccharide catabolic process involved in abscission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990076 Any cell wall polysaccharide catabolic process that is involved in abscission. GO:1990077 primosome complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990077 primosome Any of a family of protein complexes that form at the origin of replication or stalled replication forks and function in replication primer synthesis in all organisms. Early complexes initiate double-stranded DNA unwinding. The core unit consists of a replicative helicase and a primase. The helicase further unwinds the DNA and recruits the polymerase machinery. The primase synthesizes RNA primers that act as templates for complementary stand replication by the polymerase machinery. The primosome contains a number of associated proteins and protein complexes and contributes to the processes of replication initiation, lagging strand elongation, and replication restart. GO:1990078 replication inhibiting complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990078 A protein complex that inhibits multiple events of replication initiation during one replication cycle. GO:1990071 TRAPPII protein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990071 A complex that mediates intra-Golgi traffic, Golgi exit, endosome-to-Golgi traffic, and the trafficking of autophagy proteins from Golgi to the phagophore assembly site. Binds to a component of the COPI coat. In yeast it includes the following subunits: Bet3 (as homodimer), Bet5, Tca17, Trs20, Trs23, Trs31, Trs33, Trs65, Trs120, Trs130. The whole complex is thought to dimerize with itself. GO:1990072 TRAPPIII protein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990072 A complex that functions in anterograde transport at the Golgi and also regulates autophagy. In yeast it includes at least the following subunits: Bet3 (as homodimer), Bet5, Trs20, Trs23, Trs31, Trs33, Trs85. TRAPPIII may include further, as yet undescribed, proteins. GO:0039508 suppression by virus of host receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039508 inhibition by virus of host receptor activity|viral inhibition of host receptor|suppression by virus of host receptor function|downregulation by virus of host receptor activity|negative regulation by virus of host receptor activity|down-regulation by virus of host receptor activity Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the functional activity of a host receptor. GO:1990073 perforation plate biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990073 A cell wall part that is the part of a wall of a vessel member and bears one or more openings (perforations). GO:0039509 suppression by virus of host pattern recognition receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039509 down regulation by virus of host pattern recognition receptor activity|suppression by virus of host pattern recognition receptor function|inhibition by virus of host pattern recognition receptor activity|negative regulation by virus of host pattern recognition receptor activity|down-regulation by virus of host pattern recognition receptor activity|viral inhibition of host pattern recognition receptor activity Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the functional activity of a host pattern recognition receptor. A pattern recognition receptor combines with a molecular pattern based on a repeating or polymeric structure, such as a polysaccharide or peptidoglycan, to initiate a change in cell activity. GO:1990074 polyuridylation-dependent mRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990074 The chemical reactions and pathways resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of uridylyl residues (polyuridylation) at the 3' end of the target mRNA. GO:0015539 hexuronate:cation symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015539 hexuronate porter activity|hexuronate (glucuronate/galacturonate) porter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexuronate(out) + cation(out) = hexuronate(in) + cation(in). The hexuronate may be glucuronate or galacturonate. GO:1990070 TRAPPI protein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990070 TRAPP core complex A complex that tethers COPII vesicles at ER-Golgi intermediate compartment. Its role in this part of the vesicular transport may start at the ER exit sites. Binds to a component of the COPII coat. In yeast it includes the following subunits: Bet3 (as homodimer), Bet5, Trs20, Trs23, Trs31, Trs33 which are regarded as the core subunits of all TRAPP complexes in yeast. GO:0039502 suppression by virus of host type I interferon-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039502 VZ:883 inhibition of host interferon signaling pathway by virus|suppression by virus of host type I interferon-mediated signalling pathway|suppression by virus of host type I IFN-mediated signaling pathway|negative regulation by virus of host type I interferon-mediated signaling pathway Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of type I interferon-mediated signaling in the host organism. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. CL:0000482 juvenile hormone secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000482 An endocrine cell that secretes juvenile hormone. GO:0015535 fucose:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015535 RHEA:29023 fucose:hydrogen symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fucose(out) + H+(out) = fucose(in) + H+(in). CHEBI:134664 N-hydroxy-L-dihomomethioninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134664 GO:0039503 suppression by virus of host innate immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039503 inhibition of host innate immune response by virus|negative regulation by virus of host innate immune response|negative regulation by virus of host innate immunity|suppression by virus of host innate immunity Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the innate immune response of the host organism, the host's first line of defense. GO:0015536 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015536 CHEBI:134665 N,N-dihydroxy-L-dihomomethioninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134665 GO:0015537 xanthosine:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015537 xanthosine:hydrogen ion symporter activity|xanthosine permease activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: xanthosine(out) + H+(out) = xanthosine(in) + H+(in). CL:0000484 connective tissue type mast cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000484 MC(TC)|MCTC|TC mast cells Mast cell subtype whose granules contain both the serine proteases tryptase and chymase. These cells are primarily found in connective tissue, such as the peritoneal cavity, skin, and intestinal submucosa. Their development is T-cell independent. GO:0015538 sialic acid:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015538 Reactome:R-HSA-428585|RHEA:28987|Reactome:R-HSA-5624239 sialic acid permease activity|sialic acid:hydrogen symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sialate(out) + H+(out) = sialate(in) + H+(in). GO:0039501 suppression by virus of host type I interferon production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039501 VZ:875 suppression by virus of host interferon type I production|suppression by virus of host type I IFN production|negative regulation by virus of host type I interferon production Any viral process that results in the inhibition of host cell type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. CL:0000485 mucosal type mast cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000485 MC(T)|MCT|T mast cells Mast cell subtype that contains only the serine protease trypase in its granules. These cells are primarily found in mucosal tissue, such as intestinal mucosa and alveoli. They depend upon T-cells for development of phenotype. CHEBI:134663 N,N-dihydroxy-L-polyhomomethioninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134663 CHEBI:134668 N-hydroxy-L-tetrahomomethioninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134668 GO:0039506 modulation by virus of host molecular function biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039506 modification by virus of host protein function The process in which a virus effects a change in the function of a host protein via a direct interaction. CL:0000486 garland cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000486 garland nephrocyte A large binucleate cell that forms a 'garland' around the anterior end of the proventriculus (cardia) at its junction with the esophagus in both adults and larvae flies. Each cell is surrounded by a basement membrane and there are numerous micro-invaginations (lacunae) extending from the surface into the cytoplasm. At the mouth of each lacuna is a doubled filament forming a specialised filtration system (diaphragm). The filtrate is endocytosed from the lacunae. GO:0015531 citrate:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015531 RHEA:32123 citrate:hydrogen symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: citrate(out) + H+(out) = citrate(in) + H+(in). GO:0015532 alpha-ketoglutarate:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015532 alpha-ketoglutarate:hydrogen symporter activity|2-oxoglutarate:hydrogen symporter activity|2-oxoglutarate:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: alpha-ketoglutarate(out) + H+(out) = alpha-ketoglutarate(in) + H+(in). GO:0039507 suppression by virus of host molecular function biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039507 negative regulation by virus of host molecular function|down regulation by virus of host protein function|inhibition by virus of host protein function|inhibition of host protein function|negative regulation by virus of host protein function|down-regulation by virus of host protein function Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the functional activity of a host protein. CHEBI:134669 N,N-dihydroxy-L-tetrahomomethioninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134669 CL:0000487 oenocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000487 A large secretory cell found in clusters underlying the epidermis of the abdominal segments of larval abdominal segments. GO:0039504 suppression by virus of host adaptive immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039504 suppression by virus of host acquired immune response|inhibition of host adaptive immune response by virus|negative regulation by virus of host adaptive immunity|negative regulation by virus of host adaptive immune response Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the adaptive immune response of the host organism, an immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory). CL:0000488 visible light photoreceptor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000488 A photoreceptor cell that detects visible light. GO:0015533 shikimate:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015533 shikimate:hydrogen symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: shikimate(out) + H+(out) = shikimate(in) + H+(in). CHEBI:134666 N-hydroxy-L-trihomomethioninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134666 GO:0039505 suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039505 VZ:820 inhibition of host MHC class II molecule presentation by virus Any viral process that inhibits a host antigen-presenting cell expressing a peptide antigen on its cell surface in association with an MHC class II protein complex. GO:0015534 obsolete proline/glycine/betaine:hydrogen/sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015534 proline/glycine/betaine:hydrogen/sodium symporter activity|proline/glycine/betaine:proton/sodium symporter OBSOLETE. Catalysis of the reaction: (proline, glycine or betaine)(out) + (H+ or Na+)(out) = (proline, glycine or betaine)(in) + (H+ or Na+)(in). CHEBI:134667 N,N-dihydroxy-L-trihomomethioninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134667 CHEBI:76244 sapienic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76244 CHEBI:76241 O-(S-acylpantetheine-4'-phosphoryl)serine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76241 GO:0015530 shikimate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015530 Enables the transfer of shikimate from one side of a membrane to the other. Shikimate is an important intermediate in the biosynthesis of aromatic amino acids. CHEBI:76242 O-(S-acylpantetheine-4'-phosphoryl)serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76242 CHEBI:76247 4-hydroxy-2,5-dimethylfuran-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76247 CHEBI:134660 N-hydroxy-L-polyhomomethioninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134660 CHEBI:76248 4-hydroxy-2,5-dimethylfuran-3-olate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76248 CHEBI:134661 5(S),6(S)-epoxy-18(S)-hydroxy-(7E,9E,11Z,14Z,16E)-icosapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134661 CHEBI:76245 4-hydroxy-5-methyl-2-methylenefuran-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76245 CHEBI:76246 2-methyl-5-methylenefuran-3,4-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76246 GO:1990086 lens fiber cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990086 Any apoptotic process in a lens fiber cell. Lens fiber cells are elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye. GO:1990087 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990087 GO:1990088 [methyl-Co(III) methanol-specific corrinoid protein]:coenzyme M methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990088 RHEA:45208|EC:2.1.1.246 Catalysis of the reaction: a [methyl-Co(III) methanol-specific corrinoid protein] + coenzyme M = methyl-CoM + a [Co(I) methanol-specific corrinoid protein]. GO:1990089 response to nerve growth factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990089 response to nerve growth factor stimulus A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus. GO:1990082 DnaA-L2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990082 A protein complex that inhibits unwinding of DNA at the origin of replication and assembly of the pre-primosome. In E. coli, this complex is composed of DnaA and of the ribosomal protein L2. GO:1990083 DnaA-Hda complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990083 A protein complex that inactivates the function of DnaA by inhibiting the phosphorylation of DnaA-ADP to DnaA-ATP and thereby preventing multiple events of replication initiation. In E. coli, this complex is composed of DnaA and Hda. GO:1990084 DnaA-Dps complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990084 A protein complex that negatively regulates strand-opening at the origin of replication, thereby interfering with replication initiation. This complex is thought to be involved in the regulation of replication under oxidative stress conditions. In E. coli, this complex is composed of DnaA and Dps. GO:1990085 Hda-beta clamp complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990085 Hda-DnaN complex|Hda-dpo3b complex A protein complex involved in inactivating the function of DnaA and thereby preventing multiple events of replication initiation. In E. coli, this complex is composed of the beta clamp (DnaN) and Hda. GO:1990080 2-phenylethylamine receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990080 beta-phenylethylamine receptor activity Combining with the biogenic amine 2-phenylethylamine to initiate a change in cell activity. GO:1990081 trimethylamine receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990081 Combining with the biogenic amine trimethylamine to initiate a change in cell activity. GO:0015546 sulfathiazole transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015546 sulphathiazole transporter activity|bicyclomycin/sulfathiazole:hydrogen antiporter activity Enables the transfer of sulfathiazole from one side of a membrane to the other. Sulfathiazole is an antibacterial agent of the sulfonamide group. GO:0015547 nalidixic acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015547 carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity|nalidixic acid transporter activity Enables the transfer of nalidixic acid from one side of a membrane to the other. Nalidixic acid is a synthetic antibiotic that interferes with DNA gyrase and inhibits prokaryotic replication. CL:0000494 UV sensitive photoreceptor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000494 A photoreceptor cell that detects ultraviolet light. CHEBI:134673 N,N-dihydroxy-L-hexahomomethioninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134673 GO:0015548 organomercurial transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015548 organomercurial transporter activity|carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity Enables the transfer of organomercurial compounds from one side of a membrane to the other. Organomercurial substances are any organic compound containing a mercury atom. GO:0015549 carbonyl cyanide m-chlorophenylhydrazone transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015549 carbonyl cyanide m-chlorophenylhydrazone transporter activity|carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity|CCCP transporter activity Enables the transfer of carbonyl cyanide m-chlorophenylhydrazone from one side of a membrane to the other. Carbonyl cyanide m-chlorophenylhydrazone is a proton ionophore, commonly used as an uncoupling agent and inhibitor of photosynthesis because of its effects on mitochondrial and chloroplast membranes. CHEBI:76250 hydroxyisoflavans biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76250 GO:0015542 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015542 GO:0015543 obsolete lactose/glucose efflux transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015543 lactose/glucose efflux transporter activity OBSOLETE. Catalysis of the reaction: glucose or lactose(in) = glucose or lactose(out). CL:0000498 inhibitory interneuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000498 An interneuron (also called relay neuron, association neuron or local circuit neuron) is a multipolar neuron which connects afferent neurons and efferent neurons in neural pathways. Like motor neurons, interneuron cell bodies are always located in the central nervous system (CNS). CHEBI:76251 1-O-alkyl-2-arachidonoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76251 GO:0015544 phenyl propionate uniporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015544 phenyl propionate permease activity Enables the transfer of phenyl propionate from one side of a membrane to the other. CL:0000499 stromal cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000499 A connective tissue cell of an organ found in the loose connective tissue. These are most often associated with the uterine mucosa and the ovary as well as the hematopoietic system and elsewhere. GO:0015545 bicyclomycin transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015545 bicyclomycin transporter activity|bicyclomycin/sulfathiazole:hydrogen antiporter activity Enables the transfer of bicyclomycin from one side of a membrane to the other. Bicyclomycin (or bicozamycin) is an antibacterial drug often used as a livestock feed additive. GO:0015540 3-hydroxyphenyl propionate:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015540 3-hydroxyphenyl propionate porter activity|3-hydroxyphenyl propionate:hydrogen ion symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 3-hydroxyphenyl propionate(out) + H+(out) = 3-hydroxyphenyl propionate(in) + H+(in). CHEBI:52267 7-hydroxyflavonol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52267 CHEBI:76253 dTDP-4-dehydro-6-deoxy-alpha-D-gulose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76253 GO:0015541 secondary active cyanate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015541 cyanate porter activity Enables the transfer of cyanate from one side of a membrane to the other. CHEBI:52268 flavonol 3-O-[6-(4-coumaroyl)-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside]s biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52268 CHEBI:134671 N,N-dihydroxy-L-pentahomomethioninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134671 CHEBI:134672 N-hydroxy-L-hexahomomethioninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134672 CHEBI:134670 N-hydroxy-L-pentahomomethioninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134670 CL:0000492 CD4-positive helper T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000492 CD4-positive helper T lymphocyte|CD4-positive T-helper cell|CD4-positive helper T-cell|CD4-positive helper T-lymphocyte A CD4-positive, alpha-beta T cell that cooperates with other lymphocytes via direct contact or cytokine release to initiate a variety of immune functions. GO:1990097 SeqA-DNA complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990097 SeqA-hemimethylated DNA complex|SeqA-dsDNA complex|SeqA-hemimethylation dsDNA complex A protein-DNA complex that contains an oligomer of SeqA bound to GATC sites in methylated or newly-synthesized, hemi-methylated double-stranded DNA, with preference for the latter. Binding of SeqA to hemimethylated DNA sequesters oriC, prevents re-methylation of DNA by Dam and in turn stops premature re-initiation of replication during one replication cycle. GO:1990098 core primosome complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990098 core primosome A protein-DNA complex containing at least one DNA helicase and one primase. Can also contain associated proteins. The helicase component continues to unwind the double-stranded DNA (dsDNA) and the primase component synthesizes a RNA primer during initiation or restart of replication. GO:1990099 pre-primosome complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990099 prereplication complex|pre-replication complex|pre-primosome|preprimosome complex|preprimosome|pre-priming complex Any of the protein-DNA complexes that contain a DNA helicase and associated protein(s) at the origin of replication, and build up to assembling the core primosome. The associated protein(s) chaperone the helicase to the DNA, and assembly of the pre-primosome is essential for the initiation or restart of replication. Pre-primosome complexes lack a primase component. GO:1990093 obsolete negative regulation of N-methyl-D-aspartate receptor clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990093 negative regulation of N-methyl-D-aspartate receptor clustering|negative regulation of NMDA receptor clustering OBSOLETE. The negative regulation of the receptor clustering process in which N-methyl-D-aspartate (NMDA) receptors are localized to distinct domains in the cell membrane. GO:1990094 obsolete positive regulation of N-methyl-D-aspartate receptor clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990094 positive regulation of NMDA receptor clustering|positive regulation of N-methyl-D-aspartate receptor clustering OBSOLETE. The positive regulation of the receptor clustering process in which N-methyl-D-aspartate (NMDA) receptors are localized to distinct domains in the cell membrane. CL:0000469 ganglion mother cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000469 A neural progenitor cell that is the daughter of a neuroblast (sensu arthopoda). The progeny of ganglion mother cells develop into neurons, glia and (occasionally) epithelial cells. GO:1990095 positive regulation of transcription from RNA polymerase II promoter in response to reactive oxygen species biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990095 Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals. GO:1990096 positive regulation of transcription from RNA polymerase II promoter in response to superoxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990096 Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion. GO:0015517 galactose:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015517 lactose, galactose:hydrogen symporter activity|galactose:hydrogen symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose(out) + H+(out) = galactose(in) + H+(in). GO:1990090 cellular response to nerve growth factor stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990090 cellular response to NGF A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus. GO:0015518 arabinose:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015518 arabinose efflux transmembrane transporter activity|arabinose:hydrogen symporter activity|arabinose efflux permease activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: arabinose(out) + H+(out) = arabinose(in) + H+(in). CHEBI:27295 violaxanthin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27295 GO:0015519 D-xylose:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015519 D-xylose:hydrogen symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-xylose(out) + H+(out) = D-xylose(in) + H+(in). GO:1990091 sodium-dependent self proteolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990091 The sodium-dependent hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds. GO:1990092 calcium-dependent self proteolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990092 The calcium-dependent hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds. GO:0015513 high-affinity secondary active nitrite transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015513 nitrite uptake permease activity Catalysis of the transfer of nitrite from one side of the membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. CL:0000460 glucocorticoid secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000460 GO:0015514 nitrite efflux transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015514 nitrite extrusion permease activity Enables the transfer of nitrite from the inside of the cell to the outside of the cell across a membrane. GO:0015515 citrate:succinate antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015515 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: citrate(out) + succinate(in) = citrate(in) + succinate(out). GO:0015516 tartrate:succinate antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015516 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: tartrate(out) + succinate(in) = tartrate(in) + succinate(out). CHEBI:134641 hydroperoxy(epoxy)icosatrienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134641 GO:0015510 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015510 GO:0015511 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015511 CL:0000467 adrenocorticotropic hormone secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000467 corticotropin secreting cell|corticotrophin hormone secreting cell|corticotropin hormone secreting cell|ACTH secreting cell|adrenocorticotrophic hormone secreting cell A peptide hormone secreting cell that produces adrenocorticotropin, or corticotropin. GO:0015512 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015512 CHEBI:134645 hydroperoxy(hydroxy)icosapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134645 CHEBI:76265 1,2-diacyl-3-O-(beta-D-Glc-(1->6)-beta-D-Glc-(1->6)-beta-D-Glc)-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76265 CHEBI:52254 apatite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52254 CHEBI:6198 (S)-azetidine-2-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_6198 CHEBI:52255 hydroxylapatite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52255 CHEBI:76264 1,2-diacyl-3-O-(beta-D-Glc-(1->6)-beta-D-Glc)-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76264 NCBITaxon:5690 Trypanosoma organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_5690 GO:0015528 lactose:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015528 lactose, galactose:hydrogen symporter activity|lactose:hydrogen symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lactose(out) + H+(out) = lactose(in) + H+(in). GO:0015529 raffinose:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015529 raffinose:hydrogen symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: raffinose(out) + H+(out) = raffinose(in) + H+(in). GO:0015524 obsolete L-arabinose/beta-D-thiogalactopyranoside:hydrogen antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015524 L-arabinose/beta-D-thiogalactopyranoside:proton antiporter activity|L-arabinose/beta-D-thiogalactopyranoside:hydrogen antiporter activity OBSOLETE. Catalysis of the reaction: H+(out) + (L-arabinose or beta-D-thiogalactopyranoside)(in) = H+(in) + (L-arabinose or beta-D-thiogalactopyranoside)(out). GO:0015525 obsolete carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015525 carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:proton antiporter activity|carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity OBSOLETE. (Was not defined before being made obsolete). CL:0000473 defensive cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000473 A cell whose primary function is to protect the organism. GO:0015526 hexose-phosphate:inorganic phosphate antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015526 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexose phosphate(out) + inorganic phosphate(in) = hexose phosphate(in) + inorganic phosphate(out). CHEBI:134651 hydroxydocosapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134651 CL:0000474 pericardial nephrocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000474 pericardial cell An insect renal cell that filters hemolymph and is found with other pericardial nephrocytes in two rows flanking the dorsal vessel. GO:0015527 glycerol-phosphate:inorganic phosphate antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015527 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycerol phosphate(out) + inorganic phosphate(in) = glycerol phosphate(in) + inorganic phosphate(out). GO:0015520 tetracycline:proton antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015520 tetracycline:hydrogen antiporter activity|tetracyclin:proton antiporter activity|tetracyclin:hydrogen antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + tetracycline(in) = H+(in) + tetracycline(out). CHEBI:76272 kaempferol 3-O-beta-D-xyloside(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76272 CL:0000476 thyrotroph biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000476 thyroid stimulating hormone secreting cell|beta-basophil|thyrotrope A basophil cell of the anterior pituitary that produces thyroid stimulating hormone, thyrotrophin. This cell type is elongated, polygonal and lie in clusters towards the adenohypophyseal center. GO:0015521 obsolete bicyclomycin/sulfathiazole:hydrogen antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015521 bicyclomycin/sulphathiazole:hydrogen antiporter activity|bicyclomycin/sulfathiazole:proton antiporter activity|bicyclomycin/sulfathiazole:hydrogen antiporter activity OBSOLETE. Catalysis of the reaction: (bicyclomycin or sulfathiazole)(in) + H+(out) = (bicyclomycin or sulfathiazole)(out) + H+(in). CHEBI:76273 dodecanedioate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76273 GO:0015522 obsolete hydrophobic uncoupler:proton antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015522 hydrophobic uncoupler:hydrogen antiporter activity OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hydrophobic uncoupler(in) + H+(out) = hydrophobic uncoupler(out) + H+(in). Hydrophobic uncouplers include CCCP, benzalkonium and SDS. CL:0000477 ovarian follicle cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000477 follicle cell A somatic epithelial cell of the ovarian follicle/egg chamber. CHEBI:134655 desmethylanhydrotetracycline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134655 CHEBI:76270 cyclohex-1-ene-1-carbonyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76270 GO:0015523 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015523 CHEBI:76271 cyclohexane-1-carbonyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76271 CHEBI:76276 hexadecanedioate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76276 CHEBI:76275 dTDP-alpha-D-fucofuranose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76275 CHEBI:76278 dehydrocoformycin(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76278 CHEBI:76279 2''-O-acetyl-ADP-D-ribose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76279 GO:1990035 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990035 GO:1990036 calcium ion import into sarcoplasmic reticulum biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990036 The directed movement of calcium ions into a sarcoplasmic reticulum. GO:1990037 Lewy body core biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990037 NIF_Subcellular:sao6587439252 The center portion of a Lewy body. In Parkinson's disease, it contains a matted meshwork of filaments. GO:1990038 Lewy body corona biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990038 NIF_Subcellular:sao5764355747 halo The periphery of a Lewy body. In Parkinson's disease, it contains spherical accumulations of filaments arranged in a loose, radiating array. GO:1990031 pinceau fiber biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990031 NIF_Subcellular:sao109906988 Dense plexus formed by the descending collaterals of cerebellar basket cells that wrap around a Purkinje cell axonal initial segment. GO:1990032 parallel fiber biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990032 NIF_Subcellular:nlx_330 A parallel fiber results from the bifurcation of a cerebellar granule cell axon in the molecular layer into two diametrically opposed branches, that are oriented parallel to the long axis of the folium. GO:1990033 dendritic branch point biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990033 NIF_Subcellular:sao1348591767 branch point of dendrite The part of a dendritic tree where it branches, giving rise to a dendritic branch. GO:1990034 calcium ion export across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990034 calcium ion efflux from cell|calcium ion export from cell The directed movement of calcium ions from inside of a cell, across the plasma membrane and into the extracellular region. CHEBI:134628 (1E,2S)-2-methylbutanal oxime biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134628 CHEBI:134629 (1Z,2S)-2-methylbutanal oxime biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134629 CL:0000447 carbohydrate secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000447 CHEBI:134626 N-[omega-(9R,10R)-epoxy-(13R)-hydroxy-(11E)-octadecenoyloxy]acyl-beta-D-glucosyl-(1<->1)-sphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134626 CL:0000448 white fat cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000448 white adipocyte|white adipose cell|white fat cell Fat cells with light coloration and few mitochondria. They contain a scant ring of cytoplasm surrounding a single large lipid droplet or vacuole. CL:0000449 brown fat cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000449 brown adipose cell|brown adipocyte A cell from the thermogenic form of adipose tissue found in many species, particularly in newborns and hibernating mammals, but also in lesser amounts in adults of other mammals including humans. Brown fat is capable of rapid liberation of energy and seems to be important in the maintenance of body temperature immediately after birth and upon waking from hibernation. GO:1990030 pericellular basket biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990030 NIF_Subcellular:sao413722576 peri cellular basket|peri-cellular basket Ramification of basket cell axon surrounding cell bodies, forming the characteristic pericellular baskets from which the cell class derives its name. CHEBI:27273 vanadic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27273 CHEBI:27275 vanadium molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27275 CHEBI:134621 N-[omega-(linoleoyloxy)]acyl-beta-D-glucosyl-(1<->1)-sphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134621 CHEBI:76280 dTDP-3-dehydro-4,6-dideoxy-alpha-D-glucose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76280 UBERON:0009877 metapodium region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009877 cannon region|metapodium|metacarpus/metatarsus|metacarpus/metatarsus region|equine cannon region|metacarpal or metatarsal part of limb|metapodial segment Intermediate segment of the autopod, between the mesopodial region and and acropodial region. Examples: metacarpal region, metatarsal region UBERON:0010855 skin of forelimb wing biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010855 A zone of skin that is part of a forelimb wing. UBERON:0010852 fibula pre-cartilage condensation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010852 fibulal pre-cartilage condensation|fibular pre-cartilage condensation A pre-cartilage condensation that has the potential to develop into a fibula. UBERON:0009878 mesopodial skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009878 mesopodium skeleton|basipodium skeleton|skeletal parts of mesopodium|basipodium|mesopodium|carpal/tarsal skeleton|mesopodial skeleton The collection of all skeletal elements in a mesopodium. Examples: the tarsal skeleton, the carpal skeleton CL:0000440 melanocyte stimulating hormone secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000440 melanotroph|melanotrope A cell of the intermediate pituitary that produces melanocyte stimulating hormone. UBERON:0009879 tarsal skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009879 hind mesopodial skeleton|hind mesopodium|skeletal parts of hind mesopodium|hind mesopodium skeleton|set of tarsal bones|tarsalia|basipodium|mesopodium|tarsal bones set|tarsus|tarsal bones Subdivision of skeleton that consists of endochondral elements distal to the zeugopodial skeletal elements which constitute the proximal region of the posterior autopod skeleton[PHENOSCAPE:ad]. CL:0000441 follicle stem cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000441 CHEBI:134624 N-[omega-(9R)-hydroperoxy-(10E,12Z)-octadecadienoyloxy]acyl-beta-D-glucosyl-(1<->1)-sphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134624 CL:0000442 follicular dendritic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000442 A cell with extensive dendritic processes found in the B cell areas (primary follicles and germinal centers) of lymphoid tissue. They are unrelated to the dendritic cell associated with T cells. Follicular dendritic cells have Fc receptors and C3b receptors, but unlike other dendritic cells, they do not process or present antigen in a way that allows recognition by T cells. Instead, they hold antigen in the form of immune complexes on their surfaces for long periods and can present antigen to B cells during an immune response. CHEBI:76283 sebacate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76283 CL:0000443 calcitonin secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000443 CHEBI:76281 tetradecanedioate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76281 CHEBI:76282 suberate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76282 UBERON:0009870 zone of stomach biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009870 gastric zone|section of stomach|region of stomach A division of the stomach. The stomach can be divided based on mucosal histology (glandular epithelium and gastric glands) and the relative position and type of gastric gland. UBERON:0009871 nephrogenic zone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009871 nephrogenic tissue outer portion of the renal cortex. Site of formation of medullary and cortical elements. PR:000014271 ubiquitin-40S ribosomal protein S27a biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000014271 UBCEP1|RPS27A|UBA80|40S ribosomal protein S27a A protein that is a translation product of the human RPS27A gene or a 1:1 ortholog thereof. GO:1990039 hypolemmal cisterna biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990039 NIF_Subcellular:sao1634374950 hypolemmal cisternae Specialized part of the smooth endoplasmic reticulum that closely underlies the plasma membrane, usually within 60 nm or closer. CHEBI:76289 dTDP-4-dehydro-6-deoxy-alpha-D-gulose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76289 GO:1990046 stress-induced mitochondrial fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990046 SIMH|stress-induced mitochondrial hyperfusion|mitochondrial fusion in response to stress Merging of two or more mitochondria within a cell to form a single compartment, as a result of a disturbance in cellular homeostasis. GO:1990047 spindle matrix biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990047 A proteinaceous, nuclear-derived structure that embeds the microtubule spindle apparatus from pole to pole in a microtubule-independent manner during mitosis. GO:1990048 anterograde neuronal dense core vesicle transport biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_1990048 anterograde dense core granule trafficking|anterograde dense core granule transport The directed movement of substances in neuronal dense core vesicles along axonal microtubules towards the presynapse. GO:1990049 retrograde neuronal dense core vesicle transport biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_1990049 retrograde dense core granule trafficking|retrograde dense core granule transport The directed movement of neuronal dense core vesicles along axonal microtubules towards the cell body. GO:1990042 glycerol dehydrogenase [NAD(P)+] activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990042 glycerol dehydrogenase activity, NAD or NADP as acceptor Catalysis of an oxidation-reduction (redox) reaction in which glycerol is converted into glycerone and NAD+ or NADP is reduced. CHEBI:52225 UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52225 GO:1990043 5' deoxyribonuclease (pyrimidine dimer) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990043 Catalysis of the endonucleolytic cleavage immediately 5' to pyrimidine dimers to products with 5'-phosphate. CHEBI:52226 epi-cedrol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52226 GO:1990044 protein localization to lipid droplet biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990044 protein localisation to lipid particle|protein localisation to lipid droplet|protein localisation to adiposome|protein localisation to lipid body|protein localization to lipid particle|protein localization to lipid body|protein localization to adiposome A process in which a protein is transported to, or maintained in, a location on or within a lipid droplet. CHEBI:52228 (3R)-all-trans-3-hydroxyretinal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52228 GO:1990045 sclerotium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990045 The process whose specific outcome is the progression of the sclerotium over time, from its formation to the mature structure. A sclerotium is a mycelial resting body, resistant to adverse environmental conditions. CL:0000457 biogenic amine secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000457 CL:0000458 serotonin secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000458 5-Hydroxytryptamine secreting cell|5-HT secreting cell A cell type that secretes 5-Hydroxytryptamine (serotonin). CHEBI:27288 vinca alkaloid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27288 CL:0000459 noradrenergic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000459 noradrenaline secreting cell|norepinephrin secreting cell|norepinephrine secreting cell A cell capable of producting norepiniphrine. Norepiniphrine is a catecholamine with multiple roles including as a hormone and a neurotransmitter. In addition, epiniphrine is synthesized from norepiniphrine by the actions of the phenylethanolamine N-methyltransferase enzyme. GO:1990040 sub-surface cisterna biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990040 NIF_Subcellular:sao128470897 sub-surface cisternae Specialization of the hypolemmal cisterna consisting of either single profiles or closely apposed stacks of endoplasmic reticulum in which the lumen is obliterated, lying 10-20 nm beneath the plasma membrane. GO:1990041 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990041 GO:0015506 nucleoside:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015506 nucleoside:hydrogen symporter activity|nucleoside:hydrogen ion symporter activity|nucleoside permease activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nucleoside(out) + H+(out) = nucleoside(in) + H+(in). UBERON:0010850 tibia pre-cartilage condensation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010850 A pre-cartilage condensation that has the potential to develop into a tibia. CHEBI:27283 very long-chain fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27283 UBERON:0010851 fibula cartilage element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010851 fibular cartilage condensation|fibulra cartilage condensation|fibulal cartilage condensation A cartilaginous condensation that has the potential to develop into a fibula. GO:0015507 obsolete hydroxy/aromatic amino acid permease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015507 hydroxy/aromatic amino acid permease activity OBSOLETE. Permease for hydroxy and aromatic amino acids. GO:0015508 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015508 GO:0015509 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015509 GO:0015502 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015502 CHEBI:134631 L-polyhomomethionine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134631 UBERON:0010843 clavicle cartilage element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010843 A cartilaginous condensation that has the potential to develop into a clavicle. GO:0015503 glutathione-regulated potassium exporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015503 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(in) + H+(out) = K+(out) + H+(in), where glutathione maintains the closed state. CHEBI:134632 L-dihomomethionine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134632 UBERON:0010844 clavicle pre-cartilage condensation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010844 A pre-cartilage condensation that has the potential to develop into a clavicle. CHEBI:76291 nonanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76291 CL:0000451 dendritic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000451 interdigitating cell|veiled cell A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative). GO:0015504 cytosine:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015504 cytosine permease activity|cytosine:hydrogen ion symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cytosine(out) + H+(out) = cytosine(in) + H+(in). GO:0015505 uracil:cation symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015505 uracil permease activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: uracil(out) + cation(out) = uracil(in) + cation(in). CHEBI:134630 (2S)-2-methylbutanenitrile biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134630 CL:0000453 Langerhans cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000453 LC|Langerhans' cell Langerhans cell is a conventional dendritic cell that has plasma membrane part CD207. A Langerhans cell is a stellate dendritic cell of myeloid origin, that appears clear on light microscopy and has a dark-staining, indented nucleus and characteristic inclusions (Birbeck granules) in the cytoplasm; Langerhans cells are found principally in the stratum spinosum of the epidermis, but they also occur in other stratified epithelia and have been identified in the lung, lymph nodes, spleen, and thymus. CHEBI:134635 L-pentahomomethionine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134635 CHEBI:76294 kaempferol 3-O-beta-D-xyloside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76294 CL:0000454 epinephrine secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000454 adrenaline secreting cell|epinephrin secreting cell A cell capable of producing epinephrine. Epiniphrine is synthesized from norepiniphrine by the actions of the phenylethanolamine N-methyltransferase enzyme, which is expressed in the adrenal glands, androgenic neurons, and in other cell types. CHEBI:134636 L-hexahomomethionine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134636 CHEBI:76295 dTDP-alpha-D-fucofuranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76295 GO:0015500 obsolete threonine/serine:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015500 threonine/serine:sodium symporter activity OBSOLETE. Catalysis of the reaction: (threonine or serine)(out) + Na+(out) = (threonine or serine)(in) + Na+(in). CHEBI:134633 L-trihomomethionine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134633 CHEBI:76292 trans-2-nonenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76292 GO:0015501 glutamate:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015501 RHEA:29031 sodium/excitatory glutamate symporter activity|sodium/excitatory glutamate cotransporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glutamate(out) + Na+(out) = glutamate(in) + Na+(in). CHEBI:134634 L-tetrahomomethionine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134634 CL:0000456 mineralocorticoid secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000456 CHEBI:76298 22-oxodocosanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76298 CHEBI:52221 isothiocyanate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52221 CHEBI:52222 (2R)-homocitric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52222 CHEBI:76299 docosanedioate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76299 UBERON:0010849 tibia cartilage element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010849 A cartilaginous condensation that has the potential to develop into a tibia. GO:1990057 obsolete cell cycle arrest in response to DNA damage stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990057 cell cycle arrest in response to DNA damage stimulus OBSOLETE. The cell cycle regulatory process in which the cell cycle is halted during one of the normal phases (G1, S, G2, M) as a result of DNA damage from environmental insults or errors during metabolism. GO:1990058 fruit replum development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990058 The process whose specific outcome is the progression of the fruit replum over time, from its formation to the mature structure. The fruit replum is a portion of fruit placenta tissue that divides a fruit into two or more chambers and develops from a replum. GO:1990059 fruit valve development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990059 The process whose specific outcome is the progression of the fruit valve over time, from its formation to the mature structure. The fruit valve is a part of a fruit that splits apart when the fruit dehisces. GO:1990053 DNA-5-methylcytosine glycosylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990053 Catalysis of the reaction: DNA containing 5-methylcytosine + H2O = DNA with abasic site + 5-methylcytosine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the DNA 5-methylcytosine and the deoxyribose sugar to remove the 5-methylcytosine, leaving an abasic site. CHEBI:27258 uroporphyrinogen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27258 CHEBI:52214 ligand biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52214 GO:1990054 response to temozolomide biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_1990054 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temozolomide stimulus. CHEBI:52215 photochemical role biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52215 GO:1990055 phenylacetaldehyde synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990055 RHEA:55532|EC:4.1.1.109 aromatic aldehyde synthase Catalyzes the reaction: L-phenylalanine + O2 + H2O -> phenylacetaldehyde + ammonia + hydrogen peroxide + CO2. CHEBI:52216 photobiochemical role biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52216 GO:1990056 obsolete protein kinase activity required for targeting substrate to proteasomal ubiquitin-dependent protein catabolic process biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990056 protein kinase activity required for targeting substrate to proteasomal ubiquitin-dependent protein catabolic process OBSOLETE. Catalysis of the phosphorylation of an amino acid residue in a substrate protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP, thereby targeting the substrate to the proteasomal ubiquitin mediated protein catabolic process. CHEBI:52217 pharmaceutical biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52217 CL:0000424 excretory cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000424 A cell involved in the elimination of metabolic and foreign toxins, and in maintaining the ionic, acid-base and water balance of biological fluids. GO:1990050 phosphatidic acid transfer activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990050 intermembrane PA transfer activity|intermembrane phosphatidic acid transfer activity|phosphatidic acid carrier activity|phosphatidic acid transporter activity Removes a phosphatidic acid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. Phosphatidic acid refers to a glycophospholipids with, in general, a saturated fatty acid bonded to carbon-1, an unsaturated fatty acid bonded to carbon-2, and a phosphate group bonded to carbon-3. CHEBI:134607 beta-dihydromenaquinone-9 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134607 CHEBI:42896 1-thio-beta-D-glucopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_42896 GO:1990051 activation of protein kinase C activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990051 protein kinase C activation|PKC activation Any process that initiates the activity of the inactive enzyme protein kinase C. GO:1990052 ER to chloroplast lipid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990052 endoplasmic reticulum to chloroplast lipid transport|ER to chloroplast lipid trafficking The directed movement of a lipid from the endoplasmic reticulum (ER) to the chloroplast. CHEBI:27252 uronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27252 UBERON:0009854 digestive tract diverticulum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009854 intestinal pouch|diverticulum of gut Branch or outpocketing of the digestive tract. UBERON:0009856 sac biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009856 pouch|diverticulum CL:0000422 mitogenic signaling cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000422 A cell whose primary function is to cause growth by stimulating cell division in its immediate cellular environment. CL:0000423 tip cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000423 CHEBI:52210 pharmacological role biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52210 CHEBI:52211 physiological role biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52211 UBERON:0009850 nematode larva biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009850 A multicellular organism that existence_starts_and_ends_during a nematode larval stage. GO:1990068 seed dehydration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990068 The seed development process whose outcome is the drying of a maturing seed. CHEBI:52208 biophysical role biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52208 GO:1990069 stomatal opening biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990069 The process of opening of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange. CHEBI:52209 aetiopathogenetic role biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52209 GO:1990064 ground tissue pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990064 ground tissue patterning The regionalization process that gives rise to the patterning of the ground tissue. UBERON:5002389 manual digit plus metapodial segment biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_5002389 manual digit digitopodial subdivision|manual digit|manual digit ray|manual digit ( phalanges plus metapodial) plus soft tissue A subdivision of the autopod consisting of manual digit plus the region incorporating a single metapodial element. These segments are typically repeated along the pre-axiom to post-axial axis. GO:1990065 Dxr protein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990065 1-deoxy-D-xylulose 5-phosphate reductoisomerase complex A protein complex that is involved in the MEP pathway of IPP biosynthesis. It catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP). GO:1990066 energy quenching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990066 The process by which excess light energy absorbed by chlorophyll and not used to drive photosynthesis is emitted by nonphotochemical quenching or chlorophyll fluorescence. GO:1990067 intrachromosomal DNA recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990067 intrastrand DNA recombination The process of DNA recombination occurring within a single chromosome. CHEBI:52206 biochemical role biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52206 GO:1990060 maltose transport complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990060 maltose ABC transporter complex|maltose ATP-binding cassette transporter complex Protein complex facilitating ATP-dependent maltose transport through inner cell membrane (periplasm to cytoplasm) in Gram-negative bacteria. In E. coli the system is composed of a periplasmic maltose-binding protein (MBP), two integral membrane proteins, MalF and MalG, and two copies of the cytoplasmic ATP-binding cassette MalK. CHEBI:134617 epoxystearic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134617 GO:1990061 bacterial degradosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990061 The degradosome is a protein complex playing a key role in mRNA degradation and RNA processing. It includes a RNA helicase, a 3'-5' phosphate-dependent PNPase and a RNase E bound-enolase. CHEBI:27266 valine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27266 CHEBI:27267 valine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27267 GO:1990062 RPAP3/R2TP/prefoldin-like complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990062 R2TP/prefoldin-like complex A protein complex first characterized in human and comprised of a R2TP module (R2TP complex), a prefoldin-like module (containing both prefoldin-like proteins and canonical prefoldins), WD40 repeat protein Monad/WDR92 and DNA-dependent RNA polymerase subunit RPB5. This complex might have chaperone activity. CHEBI:134615 hydroperoxyoctadecatrienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134615 CHEBI:134616 2-(glutathion-S-yl)-1,4-hydroquinone(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134616 CL:0000438 luteinizing hormone secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000438 A peptide hormone secreting cell pituitary that produces luteinizing hormone. GO:1990063 Bam protein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990063 OMP complex Protein complex which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. In E. coli it is composed of BamABCDE, of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE. BamA interacts directly with BamB and the BamCDE subcomplex. CL:0000439 prolactin secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000439 A peptide hormone cell that secretes prolactin. UBERON:0009843 prostate epithelial cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009843 epithelial cord of prostate|cord of prostate epithelium A solid cord of prostate epithelium. UBERON:0009844 urogenital sinus lumen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009844 An anatomical space that surrounded_by a primitive urogenital sinus. CHEBI:134610 N-[(2S)-2-amino-2-carboxyethyl]-L-glutamate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134610 UBERON:0009845 urogenital sinus mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009845 UGM Mesenchyme that surrounds primitive urogenital sinus. UBERON:0009846 embryonic cloacal epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009846 cloacal epithelium An epithelium that is part of a embryonic cloaca. CL:0000430 xanthophore cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000430 xanthophore A pigment cell derived from the neural crest. Contains cartenoid pigments in structures called pterinosomes or xanthosomes. This gives an appearance ranging from a golden yellow to orange and red. CL:0000431 iridophore biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000431 guanophore A pigment cell derived from the neural crest. The cell contains flat light-reflecting platelets, probably of guanine, in stacks called reflecting platets or iridisomes. The color-generating components produce a silver, gold, or iridescent color. UBERON:0009847 prostate field biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009847 prostate primordium A specific region of the urogenital sinus epithelium into the area in which the prostate gland will develop. CHEBI:134613 hydroperoxyoctadecenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134613 UBERON:0009848 zona limitans intrathalamica biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009848 ZLI|MDO|ZLI organizer|mid-diencephalic organizer A narrow stripe of cells that lies between the prospective dorsal and ventral thalami. This boundary contains signals that pattern the prethalamic and thalamic territories of the future mid-diencephalon. UBERON:0009842 glandular acinus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009842 acini|acinus The many-lobed berry cluster of cells that is the terminous of a gland where the secretion is produced is acinar in form. CHEBI:66848 phosphatidylcholine 32:2 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66848 CHEBI:66849 phosphatidylcholine 32:1 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66849 GO:0039588 suppression by virus of host antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039588 VZ:815 inhibition of host proteasome antigen processing by virus Any viral process that inhibits a host antigen-presenting cell expressing a peptide antigen on its cell surface in association with an MHC protein complex. GO:0039589 obsolete suppression by virus of host TAP complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039589 VZ:817 inhibition of host TAP by virus OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of the host TAP complex, a heterodimer composed of the subunits TAP1 and TAP2 (transporter associated with antigen presentation). The TAP complex functions in the transport of antigenic peptides from the cytosol to the lumen of the endoplasmic reticulum, where they are loaded onto the MHC class I. By inhibiting the TAP complex, the virus prevents viral particles being presented at the cell surface, and thus evades the host immune response. GO:0039582 obsolete suppression by virus of host PKR activity by positive regulation of PKR nuclear localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039582 suppression by virus of host PKR activity by nuclear sequestration of PKR|suppression by virus of host PKR activity by positive regulation of PKR localization to nucleus|suppression by virus of host PKR activity by sequestering of PKR in nucleus OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host PKR (protein kinase regulated by RNA) activity by promoting the localization of PKR in the nucleus. For example, human cytomegalovirus (HMCV) gene products directly interact with PKR and inhibit its activation by sequestering it in the nucleus, away from both its activator (cytoplasmic dsRNA) and its substrate, (eIF2alpha). GO:0039583 obsolete suppression by virus of host PKR activity by positive regulation of PKR catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039583 downregulation of PKR by degradation through proteosome|promotion by virus of proteosome-dependent PKR degradation OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host PKR (protein kinase regulated by RNA) activity by promoting the degradation of PKR via the proteosome. For example, the Rift Valley fever virus (RVFV) NSs protein induces the down-regulation of PKR by degradation through proteasomes. GO:0039580 suppression by virus of host PKR activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039580 VZ:554 suppression by virus of host EIF2AK2 activity Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host PKR (protein kinase regulated by RNA) activity. Activation of PKR involves dsRNA binding followed by autophosphorylation. Phosphorylated PKR can then phosphorylate downstream targets such as the translation initiation factor eIF2 to inhibit protein synthesis. Viruses encode a number of mechanisms to inhibit the host antiviral response via PKR, including direct interaction with PKR, promoting degradation of PKR or altering the subcellular location of PKR. GO:0039581 obsolete suppression by virus of host PKR activity via double-stranded RNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039581 suppression by virus of host PKR activity by binding to dsRNA OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host PKR (protein kinase regulated by RNA) activity by interacting selectively and non-covalently with double-stranded RNA (dsRNA). Binding of viral proteins to RNA may sequester or alter the RNA so it can not be recognized by host PKR, or may compete with PKR for dsRNA binding. GO:0039586 modulation by virus of host PP1 activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039586 VZ:803 regulation by virus of host PP1 activity|modulation of host PP1 activity by virus The process in which a virus effects a change in host protein phosphatase-1 (PP1) activity, a serine/threonine phosphatase. Different viruses modulate host PP1 activity to remove phosphates from various cellular substrates and downregulate the host's antiviral response. GO:0039587 suppression by virus of host tetherin activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039587 VZ:665 suppression by virus of host BST-2 activity|inhibition of host BST2/Tetherin by virus Any process in which a virus stops, prevents, or reduces the activity of host tetherin activity. Tetherin (also known as BST2) is an alpha interferon-inducible cellular factor that impairs the release of many enveloped viruses. By blocking tetherin activity, many viruses circumvent its antiviral effects. GO:0039584 suppression by virus of host protein kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039584 Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host protein kinase activity. GO:0039585 PKR-mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039585 EIF2AK3 signal transduction|PKR signal transduction|PKR signaling pathway|signaling through PKR|EIF2AK3/PERK signaling A series of reactions in which a signal is passed on to downstream proteins within the cell via PKR (also known as EIF2AK3), an intracellular protein kinase that is activated by stress signals or upon binding to double-stranded RNA (dsRNA), followed by autophosphorylation. PKR plays a role in the antiviral response, phosphorylating proteins such as the translation initiation factor eIF2 to inhibit protein synthesis during viral infection. Begins with activation of PKR activity, and ends with regulation of a downstream cellular process, e.g. regulation of transcription or inhibition of translation. GO:1990002 methylglyoxal reductase (NADPH-dependent, acetol producing) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990002 RHEA:27986 Catalysis of the reaction: H+ + methylglyoxal + NADPH <=> hydroxyacetone + NADP+. GO:1990003 inosine-diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990003 Reactome:R-HSA-2509816|RHEA:35207|EC:3.6.1.64 inosine-diphosphatase activity|inosine diphosphatase activity|IDPase activity|IDP phosphatase activity Catalysis of the reaction: IDP + H2O = IMP + phosphate. GO:1990004 XDP phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990004 Catalysis of the reaction: XDP + H2O = XMP + phosphate. GO:1990005 granular vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990005 NIF_Subcellular:sao478230652 A cytoplasmic membrane-bounded vesicle of varying size, but usually larger than 45 nm, with an electron dense granular core, found in noradrenergic and peptidergic cells. GO:1990000 amyloid fibril formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990000 amyloid fibril assembly|amyloid structure formation|amyloid structure assembly The generation of amyloid fibrils, insoluble fibrous protein aggregates exhibiting beta sheet structure, from proteins. GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990001 Any process that prevents the activation of an inactive cysteine-type endopeptidase involved in an apoptotic process. CHEBI:66850 phosphatidylcholine 32:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66850 GO:0039579 suppression by virus of host ISG15 activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039579 VZ:723 Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host ubiquitin-like protein ISG15 activity. ISG15 is a ubiquitin-like protein that is conjugated to lysine residues on various target proteins. Viruses escape from the antiviral activity of ISG15 by using different mechanisms; the influenza B virus NS1 protein for instance blocks the covalent linkage of ISG15 to its target proteins by directly interacting with ISG15. The papain-like protease from the coronavirus cleaves ISG15 derivatives. GO:0039577 obsolete suppression by virus of host JAK1 activity by negative regulation of JAK1 phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039577 OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host JAK1 (Janus Kinase 1) activity by stopping, preventing or reducing tyrosine phosphorylation of JAK1 and thereby activation of JAK1. GO:0039578 obsolete suppression by virus of host JAK1 activity via JAK1 binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039578 OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host JAK1 (Janus Kinase 1) activity by interacting directly and selectively with JAK1. For example, the polyoma virus T antigen binds to JAK1 and renders it inactive. CHEBI:66855 phosphatidylcholine 34:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66855 CHEBI:66856 phosphatidylcholine 36:6 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66856 CHEBI:66857 phosphatidylcholine 36:1 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66857 CHEBI:66858 phosphatidylcholine 36:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66858 GO:0039571 obsolete suppression by virus of host STAT1 activity by negative regulation of STAT1 tyrosine phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039571 inhibition by virus of tyrosine phosphorylation of STAT1 OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT1 (signal transducer and activator of transcription-1) activity by stopping, preventing, or reducing the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT1 protein. For example, the measles virus V protein inhibits tyrosine phosphorylation of STAT1, thereby preventing STAT1 activation. GO:0039572 obsolete suppression by virus of host STAT2 activity by negative regulation of STAT2 tyrosine phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039572 inhibition by virus of tyrosine phosphorylation of STAT2 OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT2 (signal transducer and activator of transcription-2) activity by stopping, preventing, or reducing the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT2 protein. For example, the measles virus V protein inhibits tyrosine phosphorylation of STAT2, thereby preventing STAT2 activation. GO:0039570 obsolete suppression by virus of host STAT2 activity by negative regulation of STAT protein import into nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039570 cytoplasmic sequestering of STAT2|cytoplasmic sequestration of STAT2 OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT2 (signal transducer and activator of transcription-2) activity by retaining STAT2 in the cytoplasm, so STAT2 is unable to translocate to the nucleus to activate transcription of its target genes. GO:0039575 obsolete suppression by virus of host TYK2 activity by negative regulation of TYK2 tyrosine phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039575 inhibition by virus of host TYK2 activation|inhibition by virus of host TYK2 phosphorylation OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host TYK2 (tyrosine kinase 2) activity by stopping, preventing or reducing phosphorylation and thereby activation of TYK2. GO:1990006 amorphous vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990006 NIF_Subcellular:sao1531915298 A cytoplasmic membrane-bounded vesicle first described in dendrites, categorized by smooth membranes, electron-lucent interiors and irregular shapes. Sometimes occurs in clumps. Amorphous vesicles have been found to contain material taken up from the extracellular space, therefore suggesting that they may be part of the endosomal pathway. GO:1990007 membrane stack biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990007 NIF_Subcellular:sao2114874506 A configuration of endoplasmic reticulum (ER) found in Purkinje cells in the cerebellum and in axons in the lateral vestibular nucleus, consisting of parallel and interconnecting tubules whose outer surfaces are covered by particles or ringlike structures. GO:0039576 suppression by virus of host JAK1 activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039576 VZ:784 suppression by virus of host janus kinase 1 activity|suppression by virus of tyrosine phosphorylation of host STAT protein|viral inhibition of tyrosine phosphorylation of host STAT protein|inhibition of host JAK activity by virus|negative regulation by virus of tyrosine phosphorylation of host STAT protein|negative regulation by virus of host JAK Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host JAK1 (Janus Kinase 1) activity. In the host, binding of a ligand to a receptor triggers activation of JAK proteins, which phosphorylate tyrosine residues on the receptor creating sites for STAT proteins to bind, which are in turn phosphorylated and activated by JAK proteins. By blocking JAK1 activity, many viruses block the host signal transduction pathway. GO:1990008 neurosecretory vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990008 NIF_Subcellular:sao2031592629 A large cytoplasmic membrane-bounded vesicle with an electron dense granular core, up to 150-200 nm in diameter, found in neurosecretory cells in the hypothalamus. GO:0039573 suppression by virus of host complement activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039573 VZ:811 inhibition of host complement activation by virus|inhibition of host complement cascade by virus|inhibition of host complement factors by virus Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of complement activation. The activation of complement involves the sequential proteolysis of proteins to generate enzymes with catalytic activities. The biological functions of the complement include opsonization, inflammation, lysis of immune complexes, or enhancement of the humoral immune response. For example, the virus complement control protein (VCP) of vaccinia virus, and the complement control protein of herpesvirus inhibit C3 convertase. GO:1990009 retinal cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990009 induction of retinal programmed cell death Any apoptotic process in a retinal cell. GO:0039574 suppression by virus of host TYK2 activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039574 VZ:720 suppression by virus of host non-receptor tyrosine-protein kinase TYK2 activity Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host TYK2 (tyrosine kinase 2) activity. TYK2 is an intracellular signal-transducing tyrosine kinase that associates with the cytoplasmic tails of cytokine receptors and transmits the cytokine signal by phosphorylating receptor subunits. GO:1990013 presynaptic grid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990013 NIF_Subcellular:sao1730664005 pre-synaptic grid A hexagonal array of electron dense particles attached to the cytoplasmic face of the presynaptic membrane. GO:1990014 orthogonal array biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990014 NIF_Subcellular:sao1747012216 orthogonal array of particles|square array|OAP Square array of closely spaced intramembrane particles, 4-6 nm in size, that form supramolecular aggregates found in the plasma membrane of astrocytes, skeletal muscle and epithelial cells. They have been shown to contain aquaporins (water channels). GO:1990015 ensheathing process biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990015 NIF_Subcellular:sao1376748732 ensheathing process of Schwann cell A cell projection (often from glial cells such as Schwann cells) that surrounds an unmyelinated axon or cell soma. GO:1990016 neck portion of tanycyte biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990016 NIF_Subcellular:sao901230115 neck portion Elongated portion of a tanycyte that sticks into the periventricular layer of neuropil where it appears to contact a blood vessel; characterized by numerous cytoplasmic extensions. A tanycyte is a specialized elongated ventricular ependymal cell that has processes that extend to the outer, or pial, surface of the CNS. GO:1990010 compound eye retinal cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990010 Any apoptotic process in a compound eye retinal cell. GO:1990011 laminated body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990011 NIF_Subcellular:sao506721981 laminated inclusion body Inclusion body characterized by regularly spaced sheets of tubules arranged in a whorl pattern resembling a fingerprint. Laminated bodies have been observed in neurons of the lateral geniculate nucleus. GO:1990012 complex laminated body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990012 NIF_Subcellular:nlx_151681 CLB A cytoplasmic inclusion body found in some lateral geniculate neurons and composed of sheets of tubules (25 nm in diameter) separated by dense material (about 75 nm wide), which together with the tubules whorl give a structure resembling a fingerprint. CHEBI:66862 phosphatidylcholine 40:4 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66862 GO:0039568 obsolete suppression by virus of host STAT1 activity by inhibition of DNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039568 suppression by virus of host STAT1 activity by negative regulation of DNA binding|inhibition of DNA binding of STAT1 OBSOLETE. Any process in which a virus stops, prevents, or reduces STAT1-dependent gene transcription, by preventing STAT1 from binding to promoter sites in the nucleus. GO:0039569 obsolete suppression by virus of host STAT2 activity by positive regulation of STAT2 catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039569 targeting STAT2 for proteasome-mediated degradation|promotion by virus of proteosome-dependent STAT2 degradation|suppression by virus of host STAT2 activity by positive promotion of STAT2 proteasome-mediated degradation OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of host STAT2 (signal transducer and activator of transcription-2) by promoting the ubiquitin-dependent degradation of STAT2, mediated by the proteasome. GO:0039566 obsolete suppression by virus of host STAT1 activity by tyrosine dephosphorylation of STAT1 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039566 suppression by virus of host STAT1 activity by peptidyl-tyrosine dephosphorylation of STAT1|viral tyrosine phosphatase activity involved in suppression of host STAT1 OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT1 (signal transducer and activator of transcription-1) activity by the removal of phosphoric residues from STAT1-O-phospho-tyrosine to form STAT1-tyrosine. For example, the viral phosphatase VH1 dephosphorylates STAT1 to reverse STAT1 activation. GO:0039567 obsolete suppression by virus of host STAT1 activity by negative regulation of STAT protein import into nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039567 suppression by virus of host STAT1 activity by cytoplasmic sequestering of STAT1|cytoplasmic sequestration of STAT1 OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT1 (signal transducer and activator of transcription-1) activity by retaining STAT1 in the cytoplasm, so STAT1 is unable to translocate to the nucleus to activate transcription of its target genes. GO:0015597 obsolete histidine/arginine/lysine/ornithine porter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015597 histidine/arginine/lysine/ornithine porter activity OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + polar amino acid(out) = ADP + phosphate + polar amino acid(in). GO:0015598 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015598 CHEBI:66867 trans,polycis-decaprenyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_66867 CHEBI:66868 carboxyspermidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_66868 GO:0015599 ATPase-coupled L-glutamine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015599 EC:7.4.2.1|MetaCyc:ABC-12-RXN glutamine porter activity|ATPase-coupled glutamine transmembrane transporter activity|glutamine-importing ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + glutamine(out) -> ADP + phosphate + glutamine(in). GO:0039560 suppression by virus of host IRF9 activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039560 VZ:683 inhibition of host interferon regulatory factor-9 by virus|suppression by virus of host interferon regulatory factor 9 activity|inhibition of host IRF9 by virus Any process in which a virus stops, prevents, or reduces the activity of host IRF9 (interferon regulatory factor-9), a transcription factor involved in the innate immune response. Viral infection triggers binding of IRF9 to phosphorylated STAT1 and STAT2, forming the ISGF3 complex. The ISGF3 complex migrates to the nucleus and activates transcription of IFN-responsive genes. GO:0015593 allose transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015593 Enables the transfer of allose from one side of a membrane to the other. Allose is an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3. GO:0015594 ABC-type putrescine transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015594 EC:7.6.2.16|RHEA:29995 putrescine porter activity|putrescine-importing ATPase activity|ATPase-coupled putrescine transmembrane transporter activity Catalysis of the reaction: ATP + H2O + putrescine(out) -> ADP + phosphate + putrescine(in). GO:0039561 obsolete suppression by virus of host IRF9 activity by positive regulation of IRF9 localization to nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039561 suppression by virus of host IRF9 activity by nuclear localization of IRF9|suppression of interferon signaling by nuclear accumulation of IRF9 OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of host IRF9 (interferon regulatory factor-9) by promoting the nuclear accumulation of IRF9. For example, the reovirus mu2 protein promotes nuclear accumulation of host IRF9 by an as yet unconfirmed-mechanism. GO:0015595 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015595 GO:0015596 obsolete glycine betaine/proline porter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015596 glycine betaine/proline porter activity OBSOLETE. Catalysis of the reaction: ATP + H2O + quaternary amine(out) = ADP + phosphate + quaternary amine(in). GO:1990017 somatic portion of tanycyte biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990017 NIF_Subcellular:sao401910342 somatic portion Portion of a tanycyte that lies within the ependyma and contains the nucleus. A tanycyte is a specialized elongated ventricular ependymal cell that has processes that extend to the outer, or pial, surface of the CNS. GO:0039564 suppression by virus of host STAT2 activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039564 VZ:257 Inhibition of host STAT2 by virus|inhibition by virus of host STAT2 activity Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT2 (signal transducer and activator of transcription-2) activity. STATs are SH2 domain-containing proteins which lie downstream of many signaling receptors. Upon phosphorylation by JAKs, STAT proteins hetero- or homo-dimerize and translocate to the nucleus to activate transcription of target genes. GO:1990018 tail portion of tanycyte biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990018 NIF_Subcellular:sao1749953771 tail portion Elongated process of a tanycyte, devoid of cytoplasmic extensions, that courses through the hypothalamic nuclei to form small endfoot processes that terminate either on blood vessels or at the pial surface of the brain. A tanycyte is a specialized elongated ventricular ependymal cell. GO:0039565 obsolete suppression by virus of host STAT1 activity by positive regulation of STAT1 catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039565 targeting STAT1 for proteasome-mediated degradation|promotion by virus of proteosome-dependent STAT1 degradation|suppression by virus of host STAT1 activity by positive promotion of STAT1 proteasome-mediated degradation OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of host STAT1 (signal transducer and activator of transcription-1) by promoting the ubiquitin-dependent degradation of STAT1, mediated by the proteasome. GO:0015590 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015590 GO:0039562 suppression by virus of host STAT activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039562 inhibition by virus of host STAT activity|suppression by virus of host signal transducer and activator of transcription activity Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT (signal transducer and activator of transcription) activity. STATs are SH2 domain-containing proteins which lie downstream of many signaling receptors. Upon phosphorylation by JAKs, STAT proteins hetero- or homo-dimerize and translocate to the nucleus to activate transcription of target genes. GO:1990019 protein storage vacuole organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990019 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a protein storage vacuole, a storage vacuole that contains a lytic vacuole. GO:0015591 D-ribose transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015591 Enables the transfer of D-ribose from one side of a membrane to the other. As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12. GO:0039563 suppression by virus of host STAT1 activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039563 VZ:282 Inhibition of host STAT1 by virus|inhibition by virus of host STAT1 activity Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT1 (signal transducer and activator of transcription-1) activity. STATs are SH2 domain-containing proteins which lie downstream of many signaling receptors. Upon phosphorylation by JAKs, STAT proteins hetero- or homo-dimerize and translocate to the nucleus to activate transcription of target genes. GO:0015592 methylgalactoside transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015592 galactose/glucose (methylgalactoside) porter activity Enables the transfer of methylgalactoside from one side of a membrane to the other. Methylgalactoside is a compound in which the H of the OH group on carbon-1 of galactose is replaced by a methyl group. GO:1990024 C bouton biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990024 NIF_Subcellular:nlx_subcell_100208 Synaptic bouton found in spinal cord on the soma and proximal dendrites of motor neurons. GO:1990025 F bouton biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990025 NIF_Subcellular:nlx_subcell_100206 Synaptic bouton found in the ventral horn of the spinal cord. F boutons range in diameter from 0.5 to 7 um and contain flattened or pleomorphic synaptic vesicles. GO:1990026 hippocampal mossy fiber expansion biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990026 NIF_Subcellular:nlx_subcell_1005002 mossy fiber expansion|dentate gyrus granule cell axonal bouton|dentate gyrus mossy fiber expansion Synaptic expansion of hippocampal mossy fiber axon that makes contact with the thorny excrescences of hippocampal CA3 pyramidal cell dendrites. GO:1990027 S bouton biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990027 NIF_Subcellular:nlx_subcell_100207 Synaptic bouton found in the ventral horn of the spinal cord. S boutons range in diameter from 0.5 to 8 um and contain spherical synaptic vesicles. GO:1990020 recurrent axon collateral biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990020 NIF_Subcellular:sao1642494436 recurrent collateral Axon collateral that ramifies in the area of the soma of the cell of origin. GO:1990021 Schaffer axon collateral biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990021 NIF_Subcellular:nlx_subcell_20090511 Schaffer collateral Part of axon of a CA3 pyramidal neuron that projects to hippocampal area CA1. GO:1990022 obsolete RNA polymerase III complex import into nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990022 DNA-directed RNA polymerase III complex localization to nucleus|RNA polymerase III complex localization to nucleus|DNA-directed RNA polymerase III complex import into nucleus|RNA polymerase III complex import into nucleus|RNA polymerase III complex localisation to nucleus OBSOLETE. The directed movement of an RNA polymerase III complex from the cytoplasm to the nucleus. GO:1990023 mitotic spindle midzone biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990023 The area in the center of the anaphase spindle consisting of microtubules, microtubule bundling factors and kinesin motors where the spindle microtubules from opposite poles overlap in an antiparallel manner. CHEBI:66873 C4-dicarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_66873 CHEBI:66874 carnosinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_66874 UBERON:6000157 embryonic head segment biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_6000157 Any segment that is part of some embryonic head. UBERON:6000154 embryonic segment biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_6000154 Any segment that is part of some embryo. GO:0039557 suppression by virus of host IRF7 activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039557 VZ:653 inhibition of host IRF7 by virus|inhibition of host interferon regulatory factor-7 by virus|suppression by virus of host interferon regulatory factor 7 activity Any process in which a virus stops, prevents, or reduces the activity of host IRF7 (interferon regulatory factor-7), a transcription factor in the RIG-I/MDA-5 signaling pathway. Viral infection triggers phosphorylation of cytoplasmic IRF7, which allows IRF7 to form a homodimer, migrate to the nucleus, and activate transcription of IFN-alpha and IFN-beta genes. GO:0039558 obsolete suppression by virus of host IRF7 activity by positive regulation of IRF7 sumoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039558 suppression by virus of host interferon regulatory factor-7 activity by positive regulation of IRF7 sumoylation|promotion of IRF-7 SUMOylation OBSOLETE. Any process in which a virus stops, prevents, or reduces IRF7-dependent gene transcription, by promoting the sumoylation of IRF7, thereby disabling its activity. GO:0039555 obsolete suppression by virus of host MDA-5 activity via MDA-5 binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039555 suppression by virus of host MDA5 activity by MDA-5 binding OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of MDA-5 (also known as IFIH1) by interacting selectively and non-covalently with MDA-5 itself. For example, direct binding of viral proteins to the host MDA-5 protein can inhibit interaction of MDA-5 with MAVS, its downstream signaling effector. GO:0039556 MDA-5 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0039556 MDA5 binding Interacting selectively and non-covalently with MDA-5, a cytosolic pattern recognition receptor that initiates an antiviral signaling pathway upon binding to viral dsRNA. CHEBI:66878 pseudooxynicotinium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66878 GO:0039559 obsolete suppression by virus of host IRF7 activity by positive regulation of IRF7 catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039559 promotion by virus of proteosome-dependent IRF7 degradation OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of host IRF7 (interferon regulatory factor-7) by promoting the ubiquitin-dependent degradation of IRF7, mediated by the proteasome. CHEBI:66879 4-oxo-4-(pyridin-3-yl)butanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66879 GO:0039550 obsolete suppression by virus of host IRF3 activity by inhibition of DNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039550 inhibition by virus of host IRF3-DNA binding OBSOLETE. Any process in which a virus stops, prevents, or reduces IRF3-dependent gene transcription, by preventing or reducing IRF3 binding to promoter sites. GO:0039553 suppression by virus of host chemokine activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039553 VZ:813 downregulation by virus of host chemokine activity|inhibition by virus of host chemokine activity|down-regulation by virus of host chemokine activity|negative regulation by virus of host chemokine activity|inhibition of host chemokines by virus Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host chemokine activity. GO:1990028 intermediate voltage-gated calcium channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990028 R-type calcium channel Enables the transmembrane transfer of a calcium ion by an intermediate voltage-gated channel. An intermediate voltage-gated channel is a channel whose open state is dependent on intermediate voltage across the membrane in which it is embedded. GO:0039554 suppression by virus of host MDA-5 activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039554 VZ:603 Inhibition of host MDA5 by virus|inhibition of host IFIH1/MDA5 by virus Any process in which a virus stops, prevents, or reduces the activity of MDA-5 (also known as IFIH1). The cytoplasmic pattern recognition receptor MDA-5 detects dsRNA synthesized during active viral replication and triggers a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines. GO:1990029 vasomotion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990029 The rhythmical contraction and relaxation of arterioles, observed as slow and fast waves, with frequencies of 1-2 and 10-20 cpm. GO:0039551 obsolete suppression by virus of host IRF3 activity by positive regulation of IRF3 catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039551 promotion by virus of proteosome-dependent IRF3 degradation OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of host IRF3 (interferon regulatory factor-3) by promoting the ubiquitin-dependent degradation of IRF3, mediated by the proteasome. GO:0039552 RIG-I binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0039552 DDX58 binding|DDX58/RIG-I binding Interacting selectively and non-covalently with RIG-I, a cytosolic pattern recognition receptor that initiates an antiviral signaling pathway upon binding to viral RNA. CHEBI:76206 xenobiotic metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76206 CHEBI:66884 N-alkylglycine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66884 CHEBI:66887 (2Z,4E)-2-hydroxy-6-oxonona-2,4-dienedioate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66887 OBA:VT0010454 organism trait biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_VT0010454 The quality when measured in multicellular organism. CHEBI:66881 trans,octacis-decaprenylphospho-beta-D-ribofuranose(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66881 CHEBI:66882 4-(methylamino)butyric acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66882 GO:0015579 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015579 GO:0039546 obsolete suppression by virus of host MAVS activity by MAVS proteolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039546 viral protease cleavage of MAVS OBSOLETE. The chemical reactions and pathways performed by a virus resulting in the hydrolysis of the host MAVS (mitochondrial inhibitor of viral signaling) protein by cleavage of peptide bonds, thereby inhibiting the host innate immune response. For example, MAVS harbors a C-terminal transmembrane domain that targets it to the mitochondrial outer membrane; cleavage within this domain removes MAVS from the membrane, thus preventing it from signaling. GO:0039547 suppression by virus of host TRAF activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039547 inhibition of host TRAFs by virus Any process in which a virus stops, prevents, or reduces the activity of a host TRAF (tumor necrosis factor receptor-associated factor) protein. TRAFs are intracellular signal transducers that lie downstream of receptors including RIG-I, MDA-5 and Toll-like receptors (TLR) and transfer the signal to other intracellular signaling components. GO:0039544 obsolete suppression by virus of host RIG-I activity by RIG-I proteolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039544 cleavage of RIG-I by viral proteinase|inhibition by virus of host RIG-I activity by RIG-I proteolysis OBSOLETE. The chemical reactions and pathways performed by a virus resulting in the hydrolysis of the host RIG-I protein (also known as DDX58) by cleavage of peptide bonds, thereby inhibiting RIG-I signal transduction. GO:0039545 suppression by virus of host MAVS activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039545 VZ:704 inhibition of host MAVS by virus|suppression by virus of host mitochondrial antiviral-signaling protein Any process in which a virus stops, prevents, or reduces the activity of MAVS (mitochondrial antiviral signaling protein), a signal transducer that lies downstream of the viral RNA receptors MDA-5 and RIG-I to coordinate host innate immune responses. GO:0015575 mannitol transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015575 mannitol permease activity Enables the transfer of mannitol from one side of a membrane to the other. Mannitol is the alditol derived from D-mannose by reduction of the aldehyde group. CHEBI:66888 (2Z,4E,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66888 GO:0015576 sorbitol transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015576 glucitol permease activity|sorbitol permease activity|glucitol transporter activity Enables the transfer of sorbitol from one side of a membrane to the other. Sorbitol, also known as glucitol, is the hexitol derived by the reduction of the aldehyde group of glucose. GO:0015577 galactitol transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015577 RHEA:33143 galactitol permease activity Enables the transfer of a galactitol from one side of a membrane to the other. Galactitol is the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose. GO:0039548 suppression by virus of host IRF3 activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039548 VZ:757 inhibition of host IRF3 by virus|suppression by virus of host interferon regulatory factor 3|Inhibition of IRF3-dependent antiviral response Any process in which a virus stops, prevents, or reduces the activity of host IRF3 (interferon regulatory factor-3), a transcription factor in the RIG-I/MDA-5 signaling pathway. Viral infection triggers phosphorylation of cytoplasmic IRF3, which allows IRF3 to form a homodimer, migrate to the nucleus, and activate transcription of IFN-alpha and IFN-beta genes. GO:0015578 mannose transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015578 mannose permease activity Enables the transfer of mannose from one side of a membrane to the other. Mannose is the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins. GO:0039549 obsolete suppression by virus of host IRF3 activity by inhibition of IRF3 phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039549 inhibition of phosphorylation-induced activation of host IRF3|inhibition of virus-induced IRF-3 phosphorylation OBSOLETE. Any process in which a virus stops, prevents, or reduces the rate or extent of the phosphorylation of IRF3 (interferon regulatory factor-3), thereby inhibiting IRF3 activation. In response to signaling from RIG-1/MDA-5 receptors, IRF3 is phosphorylated on multiple serine and threonine residues; phosphorylation results in the cytoplasm-to-nucleus translocation of IRF3, DNA binding, and increased transcriptional activation of interferon-encoding genes. GO:0015571 N-acetylgalactosamine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015571 N-acetylgalactosamine permease activity Enables the transfer of N-acetylgalactosamine from one side of a membrane to the other. N-acetylgalactosamine, 2-acetamido-2-deoxygalactopyranose, is the n-acetyl derivative of galactosamine. GO:0015572 N-acetylglucosamine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015572 N-Acetyl-D-glucosamine permease|N-acetylglucosamine permease activity|D-GlcNAc transmembrane transporter activity|N-acetylchitosamine transmembrane transporter activity|N-acetyl-D-glucosamine transmembrane transporter activity Enables the transfer of N-acetylglucosamine from one side of a membrane to the other. The D isomer of N-acetylglucosamine is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein. GO:0015573 beta-glucoside transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015573 beta-glucoside permease activity Enables the transfer of beta-glucosides from one side of a membrane to the other. Beta-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in a beta configuration. GO:0015574 trehalose transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015574 trehalose permease activity Enables the transfer of trehalose from one side of a membrane to the other. Trehalose is the disaccharide alpha-D-glucopyranosyl-alpha-D-glucopyranoside that acts of a reserve carbohydrate in certain fungi, algae and lichens. GO:0039542 obsolete suppression by virus of host RIG-I K63-linked ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039542 inhibition by virus of host DDX58 K63-linked ubiquitination|inhibition by virus of host RIG-I activity by inhibition of RIG-I ubiquitination|inhibition by virus of TRIM25-mediated ubiquitination of host RIG-I OBSOLETE. Any process in which a virus stops, prevents, or reduces the rate or extent of K63-linked ubiquitination of RIG-I (also known as DDX58), thereby suppressing RIG-I signal transduction. Lys63-linked ubiquitination of the N-terminal CARD domains of RIG-I is crucial for the cytosolic RIG-I signaling pathway to elicit host antiviral innate immunity. GO:0039543 obsolete suppression by virus of host RIG-I activity by viral RNA 5' processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039543 suppression by virus of host RIG-I activity by inhibition of RNA binding OBSOLETE. The post-transcriptional removal by a virus of the 5' triphosphate group of their viral RNA, thereby preventing host RIG-I from recognizing viral RNA in the host cell. The intracellular pattern recognition receptor RIG-I (also known as DDX58) recognizes viral RNAs containing 5' triphosphates; removal by the virus of the 5'-terminal triphosphate group from their genome protects the viral RNA from RIG-recognition. GO:0039540 suppression by virus of host RIG-I activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039540 VZ:856 inhibition by virus of host RIG-I|inhibition of host DDX58/RIG-I by virus|inhibition by virus of host DDX58 activity Any process in which a virus stops, prevents, or reduces the activity of RIG-1 (also known as DDX58). The cytoplasmic pattern recognition RIG-I recognizes viral RNA synthesized during active viral replication and signals to protect the host against viral infection, for example by inducing the expression of antiviral cytokines. GO:0039541 obsolete suppression by virus of host RIG-I via RIG-I binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039541 inhibition by virus of host DDX58:MAVS binding OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of RIG-I (also known as DDX58) by interacting selectively and non-covalently with RIG-I itself. GO:0015570 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015570 CHEBI:76202 riboflavin cyclic 4',5'-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76202 CHEBI:66896 (+)-5-oxo-1,2-campholide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66896 CHEBI:66898 (3R)-11-cis-3-hydroxyretinal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66898 CHEBI:66893 4-(6-hydroxypyridin-3-yl)-4-oxobutyrate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_66893 UBERON:6000137 embryonic tagma biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_6000137 Any tagma (UBERON:6000002) that is part of some embryo (UBERON:6000052). GO:0039535 regulation of RIG-I signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039535 regulation of RIG-I signalling pathway|regulation of retinoic acid inducible gene I signaling pathway|regulation of DDX58 signaling pathway Any process that modulates the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58) binding to viral RNA. GO:0039536 negative regulation of RIG-I signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039536 negative regulation of RIG-I signalling pathway|negative regulation of retinoic acid inducible gene I signaling pathway|negative regulation of DDX58 signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58) binding to viral RNA. GO:0039533 regulation of MDA-5 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039533 regulation of IFIH1 signaling pathway|regulation of MDA5 signaling pathway|regulation of MDA-5 signalling pathway|regulation of melanoma differentiation-associated gene 5 signaling pathway Any process that modulates the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1) binding to viral RNA. GO:0039534 negative regulation of MDA-5 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039534 negative regulation of MDA-5 signalling pathway|negative regulation of melanoma differentiation-associated gene 5 signaling pathway|negative regulation of IFIH1 signaling pathway|negative regulation of MDA5 signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1) binding to viral RNA. GO:0039539 suppression by virus of host MDA-5 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039539 suppression by virus of host MDA-5 signalling pathway|inhibition by virus of host MDA-5 signaling|suppression by virus of host IFIH1 signaling pathway Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1) binding to viral RNA. This is a mechanism by which the virus evades the host innate immune response. GO:0015586 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015586 GO:0015587 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015587 GO:0039537 suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039537 suppression by virus of host RIG-like helicase signaling pathway|suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signalling pathway|suppression by virus of host cytoplasmic pattern recognition receptor signaling pathway in response to virus|suppression by virus of host RIG-I/MDA5 signaling pathway|suppression by virus of host RIG-like receptor signaling pathway|suppression by virus of host RIG-I-like receptor (RLR) signaling pathway|suppression by virus of host RLR signaling pathway Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of a virus or viral RNA binding to a pattern recognition receptor (PRR) located in the cytoplasm. This is a mechanism by which the virus evades the host innate immune response. GO:0015588 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015588 GO:0039538 suppression by virus of host RIG-I signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039538 suppression by virus of host RIG-I signalling pathway|suppression by virus of host DDX58 signaling pathway|inhibition by virus of host RIG-I signaling Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58) binding to viral RNA. This is a mechanism by which the virus evades the host innate immune response. GO:0015589 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015589 GO:0015582 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015582 GO:0015583 obsolete beta-glucoside [arbutin-salicin-cellobiose] permease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015583 beta-glucoside [arbutin-salicin-cellobiose] permease activity OBSOLETE. Catalysis of the reaction: protein N-phosphohistidine + beta-glucoside(out) = protein histidine + beta-glucoside phosphate(in). The beta-glucoside may be arbutin, salicin or cellobiose. GO:0015584 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015584 GO:0015585 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015585 GO:0039531 regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039531 regulation of viral-induced cytoplasmic pattern recognition receptor signalling pathway|regulation of MAV signaling Any process that modulates the frequency, rate or extent of the series of molecular signals generated as a consequence of a virus or viral RNA binding to a pattern recognition receptor (PRR) located in the cytoplasm. GO:0039532 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039532 negative regulation of MAVS signaling|negative regulation of viral-induced cytoplasmic pattern recognition receptor signalling pathway|negative regulation of cytoplasmic pattern recognition receptor signaling pathway in response to virus Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of a virus or viral RNA binding to a pattern recognition receptor (PRR) located in the cytoplasm. CHEBI:76215 dotriacontanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76215 GO:0015580 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015580 GO:0039530 MDA-5 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039530 MDA-5 signalling pathway|melanoma differentiation-associated gene 5 signaling pathway|IFIH1 signaling pathway|MDA5 signaling pathway Any series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1) binding to viral RNA. MDA-5 detects RNA synthesized during active viral replication and triggers a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines. GO:0015581 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015581 CHEBI:144019 5'-end phospho-(purine-ribonucleoside)(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_144019 GO:0039524 suppression by virus of host mRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039524 VZ:903 inhibition of host pre-mRNA processing by virus|inhibition of host mRNA processing by virus|negative regulation by virus of host mRNA processing|inhibition by virus of host mRNA processing Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of mRNA processing in the host cell. mRNA processing is the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide. GO:0015557 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015557 CHEBI:52290 mitogen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52290 GO:0039525 modulation by virus of host chromatin organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039525 modulation of host chromatin by virus|modulation of host chromatin structure by virus|regulation by virus of host chromatin organization|modulation by virus of host chromatin organisation Any process in which a virus effects a change in the organization of chromatin in the host. GO:0015558 secondary active p-aminobenzoyl-glutamate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015558 p-aminobenzoyl-glutamate transporter activity|p-aminobenzoyl-glutamate uptake permease activity|p-aminobenzoyl-glutamate uptake transmembrane transporter activity|p-aminobenzoyl-glutamate transmembrane transporter activity Enables the transfer of p-aminobenzoyl-glutamate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. p-aminobenzoyl-glutamate is the anion of p-aminobenzoyl-glutamic acid. GO:0039522 suppression by virus of host mRNA export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039522 VZ:902 inhibition of host mRNA nuclear export by virus|negative regulation by virus of host mRNA nuclear export|inhibition by virus of host mRNA nuclear export|suppression of host mRNA nuclear export by virus Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of movement of mRNA from the nucleus to the cytoplasm in the host organism. GO:0015559 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015559 CHEBI:134684 (E)-8-(methylsulfanyl)octanal oxime biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134684 GO:0039523 suppression by virus of host RNA polymerase II activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039523 VZ:905 inhibition of host RNA polymerase II activity by virus|negative regulation by virus of host RNA polymerase II activity|inhibition of host RNA polymerase II by virus Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host RNA polymerase II activity. CHEBI:134685 (E)-9-(methylsulfanyl)nonanal oxime biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134685 GO:0039528 cytoplasmic pattern recognition receptor signaling pathway in response to virus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039528 virus-induced cytoplasmic pattern recognition receptor signaling pathway|RIG-like helicase signaling pathway|cytoplasmic caspase-recruiting domain (CARD) helicase signaling pathway|RIG-I/MDA5 signaling pathway|RIG-I-like receptor (RLR) signaling pathway|cytoplasmic pattern recognition receptor signalling pathway in response to virus|RIG-like receptor signaling pathway|RLH signaling pathway|RLR signaling pathway Any series of molecular signals generated as a consequence of a virus or viral RNA binding to a pattern recognition receptor (PRR) located in the cytoplasm. Cytosolic PRRs such as RIG-I (DDX58) and MDA-5 (IFIH1) detect RNA synthesized during active viral replication and trigger a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines. GO:0015553 xanthosine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015553 Enables the transfer of xanthosine, xanthine riboside, from one side of a membrane to the other. GO:0039529 RIG-I signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039529 RIG-I signalling pathway|retinoic acid inducible gene I signaling pathway|DDX58 signaling pathway Any series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58) binding to viral RNA. RIG-I detects RNA synthesized during active viral replication and triggers a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines. GO:0015554 tartrate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015554 Enables the transfer of tartrate from one side of a membrane to the other. Tartrate is the anion of 2,3-dihydroxybutanedioic acid, one of the aldaric acids. The L(+) enantiomer occurs widely in plants, especially in grape juice, and in fungi and bacteria. GO:0039526 modulation by virus of host apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039526 VZ:1581 modulation of host cell apoptosis by virus|modulation by virus of host apoptosis|regulation by virus of host apoptosis Any process in which a virus modulates the frequency, rate or extent of apoptosis of infected host cells. GO:0015555 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015555 GO:0015556 C4-dicarboxylate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015556 Enables the transfer of C4-dicarboxylate from one side of a membrane to the other. GO:0039527 suppression by virus of host TRAF-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039527 suppression by virus of host tumor necrosis factor receptor-associated factor signaling|negative regulation by virus of host TRAF-mediated signal transduction|inhibition of host TRAF-mediated signal transduction by virus Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of TRAF-mediated signal transduction in the host. GO:0015550 galacturonate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015550 Enables the transfer of galacturonate from one side of a membrane to the other. Galacturonate is the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group. CHEBI:76222 1-O-acyl-N-acylsphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76222 GO:0015551 3-hydroxyphenyl propanoate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015551 3-hydroxyphenyl propionate transmembrane transporter activity Enables the transfer of 3-hydroxyphenyl propanoate from one side of a membrane to the other. CHEBI:76220 omega-hydroxytriacontanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76220 GO:0015552 propionate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015552 Enables the transfer of propionate from one side of a membrane to the other. Propionate (or propanoate) is the organic acid CH3-CH2-COOH. GO:0039520 induction by virus of host autophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039520 VZ:846 positive regulation by virus of host autophagy|activation of host autophagy by virus Any process in which a virus activates or increases the frequency, rate or extent of autophagy in the host. CHEBI:134682 (E)-5-(methylsulfanyl)pentanal oxime biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134682 CHEBI:76225 1-alkyl-3-acylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76225 CHEBI:134683 (E)-7-(methylsulfanyl)heptanal oxime biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134683 GO:0039521 suppression by virus of host autophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039521 VZ:845 negative regulation by virus of host autophagy|inhibition by virus of host autophagy|inhibition of host autophagy by virus Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of autophagy in the host. CHEBI:76226 N-hexanoyldihydroceramide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76226 CHEBI:134680 omega-(methylsulfanyl)-(E)-alkanal oxime biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134680 CHEBI:76224 aromatic ketone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76224 CHEBI:134681 (E)-6-(methylsulfanyl)hexanal oxime biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134681 CHEBI:76238 protopanaxadiol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76238 GO:0039519 modulation by virus of host autophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039519 regulation by virus of host autophagy Any process in which a virus effect a change in the frequency, rate or extent of autophagy in the host. GO:0015568 L-idonate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015568 L-idonate/D-gluconate:hydrogen symporter activity Enables the transfer of L-idonate from one side of a membrane to the other. L-idonate is an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose. GO:0039513 suppression by virus of host catalytic activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039513 negative regulation by virus of host catalytic activity|downregulation by virus of host catalytic activity|down-regulation by virus of host enzyme activity|inhibition by virus of host catalytic activity Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host enzyme activity. GO:0015569 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015569 GO:0039514 suppression by virus of host JAK-STAT cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039514 downregulation by virus of host JAK-STAT cascade|inhibition by virus of host JAK-STAT cascade|negative regulation by virus of host JAK-STAT cascade|down-regulation by virus of host JAK-STAT cascade Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the JAK-STAT signal cascade in the host organism. CHEBI:52280 isopimara-7,15-diene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52280 GO:0039511 suppression by virus of host interferon receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039511 VZ:843 down-regulation by virus of host interferon receptor activity|negative regulation by virus of host interferon receptor activity|inhibition of host interferon receptors by virus|downregulation by virus of host interferon receptor activity|inhibition by virus of host interferon receptor activity Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the functional activity of a host interferon receptor. GO:0039512 suppression by virus of host protein tyrosine kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039512 negative regulation by virus of host protein tyrosine kinase activity|down-regulation by virus of host protein tyrosine kinase activity|downregulation by virus of host protein tyrosine kinase activity|inhibition by virus of host protein tyrosine kinase activity Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host protein tyrosine kinase activity. GO:0015564 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015564 GO:0039517 modulation by virus of host protein serine/threonine phosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039517 modulation by virus of protein serine/threonine phosphatase activity in host|regulation by virus of host protein serine/threonine phosphatase activity The process in which a virus effects a change in host protein serine/threonine phosphatase activity. GO:0039518 suppression by virus of host cytokine activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039518 downregulation by virus of host cytokine activity|negative regulation by virus of host cytokine activity|down-regulation by virus of host cytokine activity|inhibition by virus of host cytokine activity Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host cytokine activity. GO:0015565 threonine efflux transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015565 threonine efflux permease activity|threonine export transporter activity|threonine export protein Enables the transfer of threonine from the inside of the cell to the outside of the cell across a membrane. GO:0015566 acriflavine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015566 acriflavin resistant pump activity|acriflavine transporter activity|acriflavin transporter activity Enables the directed movement of acriflavin from one side of a membrane to the other. Acriflavin is a fluorescent dye used as a local antiseptic and also as a biological stain. It intercalates into nucleic acids thereby inhibiting bacterial and viral replication. GO:0039515 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0039515 GO:0015567 alkane transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015567 Enables the transfer of alkanes from one side of a membrane to the other. Alkanes are saturated aliphatic hydrocarbon compounds. GO:0039516 modulation by virus of host catalytic activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039516 modulation of catalytic activity of host by virus|regulation by virus of host catalytic activity|regulation of host catalytic activity by virus The process in which a virus effects a change in host enzyme activity. GO:0015560 obsolete L-idonate/D-gluconate:hydrogen symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015560 L-idonate/D-gluconate:hydrogen symporter activity|L-idonate/D-gluconate:proton symporter OBSOLETE. Catalysis of the reaction: (L-idonate or D-gluconate)(out) + H+(out) = (L-iodonate or D-gluconate)(in) + H+(in). GO:0015561 rhamnose:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015561 rhamnose:hydrogen symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: rhamnose(out) + H+(out) = rhamnose(in) + H+(in). CHEBI:76233 2-linoleoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76233 CHEBI:52288 1-octadec-9-enoylglycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52288 GO:0015562 efflux transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015562 monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity|efflux permease activity Enables the transfer of a specific substance or related group of substances from the inside of the cell to the outside of the cell across a membrane. CHEBI:52289 wortmannin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52289 GO:0015563 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015563 CHEBI:76231 2-oleoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76231 CHEBI:52283 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52283 CHEBI:76236 (R)-2-hydroperoxy-alpha-linolenic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76236 GO:0039510 suppression by virus of host ATP-dependent RNA helicase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039510 negative regulation by virus of host ATP-dependent RNA helicase activity|down-regulation by virus of host ATP-dependent RNA helicase activity|inhibition by virus of host ATP-dependent RNA helicase activity|downregulation by virus of host ATP-dependent RNA helicase activity Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host ATP-dependent RNA helicase activity. CHEBI:52285 1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52285 CHEBI:76234 (R)-2-hydroxy-alpha-linolenic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76234 CHEBI:76235 (8Z,11Z,14Z)-heptadecatrienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76235 GO:0098046 type V protein secretion system complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098046 T5SS complex|autotransporter system complex A complex of proteins that permits the translocation of proteins across the outer membrane via a transmembrane pore, formed by a beta-barrel, into the extracellular milieu or directly into host cells; the secreted proteins contain all the information required for translocation of an effector molecule through the cell envelope. The type V secretion systems includes the autotransporters (type Va), the two-partner secretion system (type Vb) and the Oca family (type Vc). GO:0098045 virus baseplate assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098045 The aggregation, arrangement and bonding together of a set of components to form a virus baseplate. CHEBI:17828 2,3-dihydroxyindole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17828 CHEBI:17826 methylarsonous acid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17826 CHEBI:17827 methyl-CoM biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17827 CHEBI:17824 propan-2-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17824 CHEBI:17825 7-methylguanosine 5'-phosphate(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17825 CHEBI:17822 serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17822 CHEBI:17823 calcitriol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17823 CHEBI:17820 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17820 CHEBI:17821 thymine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17821 GO:1990400 mitochondrial ribosomal large subunit rRNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990400 21S rRNA binding|mitochondrial LSU rRNA binding Interacting selectively and non-covalently with the mitochondrial large ribosomal subunit RNA (LSU rRNA), a constituent of the mitochondrial large ribosomal subunit. GO:1990401 embryonic lung development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990401 The process occurring during the embryonic phase whose specific outcome is the progression of the lung over time, from its formation to the mature structure. UBERON:0010498 pseudostratified columnar epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010498 A simple columnar epithelium that looks stratified but is not, because its cells are arranged with their nuclei at different levels. UBERON:0010499 pseudostratified ciliated columnar epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010499 epithelium pseudostratificatum columnare ciliatum (trachea et bronchi) Epithelium composed of a single layer of cells, appearing as layered because the column-shaped cells vary in height so the nuclei are at different levels. The basal portions of all the cells are in contact with the basement membrane. It lines the respiratory system and the male reproductive tract. The cilia in the respiratory tract are motile, while the stereocilia in the male reproductive tract are immobile. CHEBI:17817 CDP-4-dehydro-3,6-dideoxy-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17817 CHEBI:17818 N-feruloyltyramine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17818 CHEBI:17815 1,2-diacyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17815 CHEBI:17816 1D-myo-inositol 1,4-bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17816 CHEBI:17813 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17813 CHEBI:17814 salicin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17814 CHEBI:17811 2,4,6/3,5-pentahydroxycyclohexanone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17811 CHEBI:17810 1-O-(alk-1-enyl)-2-O-acyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17810 GO:1990406 CGRP receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990406 IntAct:EBI-9009008 calcitonin gene-related polypeptide receptor complex|CGRP-R complex|Calcitonin-gene-related peptide receptor complex A transmembrane, G protein-coupled signalling receptor complex recognized by calcitonin gene-related peptides (CGRP). GO:1990407 calcitonin gene-related peptide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990407 calcitonin-gene-related peptide binding|CGRP polypeptide binding|calcitonin-gene-related polypeptide binding Interacting selectively and non-covalently with calcitonin gene-related peptide (CGRP). GO:1990408 calcitonin gene-related peptide receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990408 calcitonin-gene-related peptide receptor signaling pathway|calcitonin-gene-related polypeptide receptor signaling pathway|CGRP receptor signaling pathway A series of molecular signals initiated by an extracellular calcitonin gene-related peptide (CGRP) combining with a calcitonin gene-related peptide receptor on the surface of the target cell. Calcitonin gene-related peptide receptors may form dimers, trimers or tetramers. GO:1990409 adrenomedullin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990409 AM binding Interacting selectively and non-covalently with adrenomedullin (AM). GO:1990402 embryonic liver development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990402 The process occurring during the embryonic phase whose specific outcome is the progression of the liver over time, from its formation to the mature structure. GO:1990403 embryonic brain development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990403 The process occurring during the embryonic phase whose specific outcome is the progression of the brain over time, from its formation to the mature structure. GO:1990404 protein ADP-ribosylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990404 ribosylase activity The transfer, from NAD, of ADP-ribose to a protein amino acid residue. GO:1990405 protein antigen binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990405 Interacting selectively and non-covalently with a protein antigen. GO:0098026 virus tail, tube biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098026 bacteriophage tail tube The internal tube of the contractile tails of some viruses. The virus tail tube is the channel for DNA ejection into the host cytoplasm. GO:0098027 virus tail, sheath biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098027 bacteriophage tail sheath The external contractile envelope of the tail of some viruses. Its contraction ensures ejection of the virus DNA into the host cytoplasm. GO:1990410 adrenomedullin receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990410 AM receptor signaling pathway A series of molecular signals initiated by an extracellular adrenomedullin combining with a dimeric adrenomedullin receptor on the surface of the target cell. GO:1990411 hercynylcysteine sulfoxide lyase activity (ergothioneine-forming) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990411 MetaCyc:RXN-14428|RHEA:42688 Catalysis of the reaction: hercynylcysteine sulfoxide + 2H+ = ergothioneine + pyruvate + ammonium. GO:0098024 virus tail, fiber biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098024 bacteriophage tail fiber The fibrous region of the virus tail used to scan, recognize and attach to the host cell. GO:0098025 virus tail, baseplate biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098025 bacteriophage baseplate|tail tip|tail structure Multiprotein component at the distal (head) end of the virus tail to which fibers of tailed viruses may be attached. GO:1990412 hercynylselenocysteine lyase activity (selenoneine-forming) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990412 RHEA:42696 Catalysis of the reaction: hercynylselenocysteine + 2H+ = selenoneine + pyruvate + ammonium. GO:0098022 viral capsid, fiber biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098022 head/capsid fiber A type of capsid decoration composed of fiber structures. GO:0098023 virus tail, tip biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098023 bacteriophage tail tip The basal end of the virus tail, which is used by the virus to attach to the host cell. GO:0098020 obsolete virus tail, minor subunit biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098020 bacteriophage minor protein subunit|minor tail protein OBSOLETE. The part of the viral tail that comprises the least common subunit type. GO:0098021 viral capsid, decoration biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098021 decoration protein Component of the virus capsid (head), located on the outer head surface. Involved in the stabilization of the head structure and usually non-essential. CHEBI:17848 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17848 CHEBI:17849 glucarolactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17849 CHEBI:17846 (S)-naringenin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17846 CHEBI:17847 p-cresol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17847 CHEBI:17844 2-amino-3-oxobutanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17844 CHEBI:17845 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17845 CHEBI:17842 trypanothione biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17842 CHEBI:17843 transfer RNA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17843 GO:1990417 snoRNA release from pre-rRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990417 The release of snoRNA from pre-rRNA. UBERON:0009494 pharyngeal arch mesenchymal region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009494 branchial arch mesenchyme|pharyngeal arch mesenchyme A portion of mesenchymal tissue associated with an individual pharyngeal arch. CHEBI:17840 indoxyl biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17840 GO:1990418 response to insulin-like growth factor stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990418 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin-like growth factor stimulus. GO:1990419 obsolete response to elemental metal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990419 response to elemental metal OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an elemental metal stimulus. UBERON:0009497 epithelium of foregut-midgut junction biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009497 An epithelium that is part of a foregut-midgut junction. GO:1990413 eyespot apparatus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990413 stigma|eyespot A small pigmented organelle used in single-celled organisms to detect light. GO:1990414 replication-born double-strand break repair via sister chromatid exchange biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990414 replication-born DSB repair by SCE The repair of a replication-born double-strand DNA break in which the DNA molecule is repaired using the homologous sequence of the sister chromatid which serves as a template to repair the breaks. GO:0098028 virus tail, shaft biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098028 bacteriophage tail shaft The tube of the non-contractile tails of some viruses. GO:1990415 Pex17p-Pex14p docking complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990415 A protein complex involved in the peroxisomal import machinery. In S. cerevisiae, this complex contains the proteins Pex17p, Pex14p, Pex19, and Pex13p. GO:1990416 cellular response to brain-derived neurotrophic factor stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990416 cellular response to BDNF stimulus A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brain-derived neurotrophic factor stimulus. GO:0098029 icosahedral viral capsid, spike biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098029 A short structure attached to an icosahedral virion capsid, and used for attachment to the host cell. GO:0098037 viral DNA genome packaging, 5' extended cos packaging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098037 The encapsulation of the viral DNA genome within the capsid, which proceeds via cleavage of the viral DNA at specific sites to produce 5' protruding ends. GO:1990420 establishment of septation initiation network asymmetry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990420 establishment of SIN asymmetry The septation initiation signaling process by which the activity of the septation initiation network (SIN) is activated asymmetrically on the spindle pole bodies. GO:0098038 non-replicative transposition, DNA-mediated biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098038 cut-and-paste transposition Process by which a transposable element is excised from the donor site and integrated at the target site without replication of the element. Also referred to as cut-and-paste transposition. GO:1990421 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990421 GO:1990422 glyoxalase (glycolic acid-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990422 Catalysis of the reaction: glyoxal + H2O = glycolic acid. Catalysis occurs in the absence of a cofactor. GO:0098035 viral DNA genome packaging via site-specific sequence recognition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098035 The encapsulation of the viral DNA genome within the capsid, which proceeds via cleavage of the viral DNA at specific sites by a viral terminase. GO:1990423 RZZ complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990423 Rod-Zwilch-Zw10 complex A kinetochore component required for both meiotic and mitotic spindle assembly checkpoints. GO:0098036 viral DNA genome packaging, 3' extended cos packaging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098036 The encapsulation of the viral DNA genome within the capsid, which proceeds via cleavage of the viral DNA at specific sites to produce 3' protruding ends. GO:0098033 icosahedral viral capsid, neck fiber biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098033 A fiber attached to the neck at the base of some icosahedral viral capsids. UBERON:0009480 endoderm of buccopharyngeal membrane biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009480 An endoderm that is part of a buccopharyngeal membrane. GO:0098031 icosahedral viral capsid, collar biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098031 A small disk located at the base of some icosahedral virus capsids. GO:0098032 icosahedral viral capsid, collar fiber biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098032 A fiber attached to the collar structure of some icosahedral viral capsids. UBERON:0009482 associated mesenchyme of foregut-midgut junction biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009482 Mesenchyme that is part of a foregut-midgut junction. GO:0098030 icosahedral viral capsid, neck biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098030 A region of constriction located below the head and above the tail sheath of viruses with contractile tails (Myoviridae). CHEBI:17839 7,8-dihydropteroate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17839 CHEBI:17837 D-tagatose 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17837 CHEBI:17838 (3S)-3-hydroxy-L-aspartate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17838 CHEBI:17835 2-phospho-D-glyceric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17835 CHEBI:17836 4-aminobenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17836 CHEBI:17833 gentamycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17833 CHEBI:17831 heparosan-N-sulfate D-glucuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17831 CHEBI:17832 1-O-(alk-1-enyl)-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17832 GO:1990428 miRNA transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990428 microRNA transport The directed movement of microRNA (miRNA) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. UBERON:0009483 mesentery of foregut-midgut junction biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009483 foregut-midgut junction mesentery A mesentery that is part of a foregut-midgut junction. GO:1990429 peroxisomal importomer complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990429 peroxisomal import pore|Pex14 complex|peroxisomal protein import machinery A protein complex responsible for transporting proteins into the peroxisomal matrix. An example of this complex is Pex14 found in S. cerevisae which has 9 core components and 12 transient interaction partners. CHEBI:17830 7,8-diaminononanoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17830 GO:1990424 protein arginine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990424 Catalysis of the reaction: ATP + a protein arginine = ADP + protein arginine phosphate. GO:1990425 ryanodine receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990425 IntAct:EBI-9632656 RyR A voltage-gated calcium-release channel complex of the sarcoplasmic or endoplasmic reticulum. It plays an important role in the excitation-contraction (E-C) coupling of muscle cells. RyR comprises a family of ryanodine receptors, widely expressed throughout the animal kingdom. GO:0098039 replicative transposition, DNA-mediated biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098039 transpositional DNA genome replication|copy-and-paste transposition Process of transposition in which the existing element is replicated and one of the copies is excised and integrated at a new target site. Also referred to as copy-and-paste transposition. GO:1990426 mitotic recombination-dependent replication fork processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990426 homologous recombination dependent replication fork recovery|homologous recombination-dependent replication fork processing Replication fork processing that includes recombination between DNA near the arrested fork and homologous sequences. Proteins involved in homologous recombination are required for replication restart. GO:1990427 stereocilia tip-link density biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990427 An electron-dense plaque at either end of a stereocilia tip link that provides the anchor in the stereocilia membrane. GO:0098061 viral capsid, internal space biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098061 internal head protein The region of a virus contained within the capsid shell, and usually containing the viral genome and accessory proteins. CHEBI:17808 IDP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17808 CHEBI:17806 N-acetyl-beta-D-galactosaminyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17806 CHEBI:17807 3-(3,4-dihydroxyphenyl)lactic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17807 CHEBI:17804 dyspropterin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17804 CHEBI:17805 D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17805 CHEBI:17802 pseudouridine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17802 CHEBI:134288 phosphatidic acid 18:3 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134288 CHEBI:134289 xanthohumol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134289 CHEBI:17803 dehydro-D-arabinono-1,4-lactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17803 CHEBI:17800 O-phosphoviomycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17800 CHEBI:17801 4-hydroxy-4-methyl-2-oxoglutaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17801 CHEBI:134283 keto-D-tagatose 6-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134283 CHEBI:134286 O-succinyl-L-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134286 CHEBI:134284 keto-L-tagatose 6-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134284 CHEBI:134299 phosphatidylcholine 13:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134299 CARO:0001010 organism or virus or viroid biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/CARO_0001010 CHEBI:134298 phosphatidylcholine 12:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134298 GO:0050026 L-glycol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050026 MetaCyc:L-GLYCOL-DEHYDROGENASE-RXN|EC:1.1.1.185 L-(+)-glycol:NAD(P) oxidoreductase activity|L-glycol:NAD(P)+ oxidoreductase activity|glycol (nicotinamide adenine dinucleotide (phosphate)) dehydrogenase activity|L-glycol:NAD(P) dehydrogenase activity Catalysis of the reaction: an L-glycol + NAD(P)+ = a 2-hydroxycarbonyl compound + NAD(P)H + H+. GO:0050027 obsolete L-idonate 2-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050027 MetaCyc:L-IDONATE-2-DEHYDROGENASE-RXN|RHEA:21176|EC:1.1.1.128 5KGR|reductase, 5-ketogluconate 5- (L-idonate-forming)|5-ketogluconate 2-reductase activity|L-idonate 2-dehydrogenase activity|5-keto-D-gluconate 2-reductase activity|L-idonate:NADP+ 2-oxidoreductase activity|5-ketoglucono-idono-reductase activity|L-idonate dehydrogenase activity OBSOLETE. Catalysis of the reaction: L-idonate + NADP+ = 5-dehydro-D-gluconate + NADPH. GO:0050024 L-galactonolactone oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050024 MetaCyc:1.3.3.12-RXN|RHEA:20617|EC:1.3.3.12|KEGG_REACTION:R00643 L-xylono-1,4-lactone oxidase activity|L-galactono-1,4-lactone oxidase activity|L-galactono-1,4-lactone:oxygen 3-oxidoreductase activity Catalysis of the reaction: L-galactono-1,4-lactone + O(2) = L-ascorbate + H(2)O(2) + H(+). GO:0050025 L-glutamate oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050025 RHEA:20728|EC:1.4.3.11|MetaCyc:L-GLUTAMATE-OXIDASE-RXN glutamate (acceptor) dehydrogenase activity|glutamate oxidase activity|glutamic dehydrogenase (acceptor)|L-glutamate:oxygen oxidoreductase (deaminating)|L-glutamic acid oxidase activity|glutamic acid oxidase activity Catalysis of the reaction: L-glutamate + O2 + H2O = 2-oxoglutarate + NH3 + H2O2. CHEBI:27237 uridine phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27237 GO:0050028 L-lysine-lactamase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050028 MetaCyc:L-LYSINE-LACTAMASE-RXN|RHEA:21388|EC:3.5.2.11|KEGG_REACTION:R00463 L-alpha-aminocaprolactam hydrolase activity|L-lysine-1,6-lactam lactamhydrolase activity|L-lysinamidase activity Catalysis of the reaction: L-2-aminohexano-6-lactam + H(2)O = L-lysine. GO:0050029 L-lysine oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050029 MetaCyc:L-LYSINE-OXIDASE-RXN|EC:1.4.3.14|KEGG_REACTION:R00447|RHEA:14437|MetaCyc:PWY-5311 L-lysyl-alpha-oxidase activity|L-lysine:oxygen 2-oxidoreductase (deaminating)|L-lysine alpha-oxidase activity Catalysis of the reaction: L-lysine + H(2)O + O(2) = 6-amino-2-oxohexanoate + H(2)O(2) + NH(4)(+). CHEBI:27232 uridine 5'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27232 CL:0000765 erythroblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000765 normoblast A nucleated precursor of an erythrocyte that lacks hematopoietic lineage markers. CL:0000766 myeloid leukocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000766 A cell of the monocyte, granulocyte, or mast cell lineage. CL:0000767 basophil biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000767 basophilic leucocyte|basophilic leukocyte|polymorphonuclear leucocyte|polymorphonuclear leukocyte Any of the immature or mature forms of a granular leukocyte that in its mature form has an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse, bluish-black granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation. A basophil is CD123-positive, CD193-positive, CD203c-positive, and FceRIa-positive. CL:0000768 immature basophil biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000768 immature basophilic leukocyte|immature basophilic leucocyte Any of the immature forms of a basophil, in which basophilic specific granules are present but other phenotypic features of the mature form may be lacking. UBERON:0010421 spleen B cell corona biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010421 spleen B-cell corona|splenic B cell corona|splenic corona|spleen lymphocytic corona|spleen B cell corona|follicle mantle|spleen mantle zone|B lymphocyte domain of the spleen|lymphocytic corona|B cell domain of the spleen The area of the (spleen) secondary B follicle that surrounds the germinal center and harbors the small recirculating B lymphocytes CL:0000769 basophilic metamyelocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000769 A basophil precursor in the granulocytic series, being a cell intermediate in development between a basophilic myelocyte and a band form basophil. The nucleus becomes indented where the indentation is smaller than half the distance to the farthest nuclear margin; chromatin becomes coarse and clumped; specific granules predominate while primary granules are rare. Markers are CD11b-positive, CD15-positive, CD16-positive, CD24-positive, CD33-positive, and CD13-positive. UBERON:0010422 primary nodular lymphoid tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010422 primary lymphoid follicle|primary lymphoid nodule|primary follicle A lymphoid follicle containing naive B cells UBERON:0010420 lymph node follicular corona biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010420 lymph node inactive zone|lymph node B cell corona|lymph node dark zone|lymph node peripheral zone|lymph node follicular mantle A part of the secondary follicle in which naive B cells reside along with some helper T cells, macrophages and follicular dendritic cells; these are displaced by the expanding germinal centre and form a 'mantle' around it UBERON:0010412 epididymal fat pad biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010412 periepididymal fat pad encapsulated adipose tissue associated with the epididymis UBERON:0010418 urethral opening biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010418 urethral orifice An orifice that is part of a lower urinary tract. CL:0000762 nucleated thrombocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000762 A nucleated blood cell involved in coagulation, typically seen in birds and other non-mammalian vertebrates. UBERON:0010416 lymph node B cell domain biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010416 nodular lymph node cortex|lymph node B-cell domain|lymph node B cell dependent cortex A part of the lymph node cortex in which B lymphocytes home to primary follicles to survey follicular dendritic cells (FDCs); antigen stimulated B cells proliferate and differentiate within the follicles forming distinctive germinal centers CL:0000763 myeloid cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000763 A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage. UBERON:0010417 lymph node T cell domain biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010417 lymph node deep cortex|lymph node T cell dependent paracortex|lymph node T-cell domain|T cell zone of lymph node|lymph node T zone|T zone of lymph node The paracortex and interfollicular cortex of the lymph node in which T lymphocytes home to survey dendritic cells CL:0000764 erythroid lineage cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000764 erythropoietic cell A immature or mature cell in the lineage leading to and including erythrocytes. GO:0050022 L-arabinose 1-dehydrogenase (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050022 MetaCyc:L-ARABINOSE-1-DEHYDROGENASE-RXN|EC:1.1.1.46|RHEA:17925 L-arabinose 1-dehydrogenase activity|L-arabinose:NAD+ 1-oxidoreductase activity Catalysis of the reaction: L-arabinose + NAD+ = L-arabinono-1,4-lactone + NADH. GO:0050023 L-fuconate dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050023 MetaCyc:L-FUCONATE-HYDRATASE-RXN|EC:4.2.1.68|KEGG_REACTION:R03688|RHEA:22772 L-fuconate hydro-lyase activity|L-fuconate hydro-lyase (2-dehydro-3-deoxy-L-fuconate-forming)|L-fuconate hydratase activity Catalysis of the reaction: L-fuconate = 2-dehydro-3-deoxy-L-fuconate + H(2)O. GO:0050020 L-arabinonate dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050020 MetaCyc:L-ARABINONATE-DEHYDRATASE-RXN|RHEA:20968|EC:4.2.1.25|KEGG_REACTION:R02522 L-arabinonate hydro-lyase activity|L-arabonate dehydrase activity|L-arabinonate hydro-lyase (2-dehydro-3-deoxy-L-arabinonate-forming)|L-arabonate dehydratase activity Catalysis of the reaction: L-arabinonate = 2-dehydro-3-deoxy-L-arabinonate + H(2)O. GO:0050021 L-arabinonolactonase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050021 MetaCyc:L-ARABINONOLACTONASE-RXN|EC:3.1.1.15|KEGG_REACTION:R02526|RHEA:16217 L-arabinono-1,4-lactone lactonohydrolase activity Catalysis of the reaction: L-arabinono-1,4-lactone + H(2)O = L-arabinonate + H(+). GO:0050037 L-xylose 1-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050037 MetaCyc:L-XYLOSE-1-DEHYDROGENASE-RXN|RHEA:15789|KEGG_REACTION:R03586|EC:1.1.1.113 L-xylose:NADP+ 1-oxidoreductase activity|L-xylose dehydrogenase activity|NADPH-xylose reductase activity Catalysis of the reaction: aldehydo-L-xylose + NADP(+) = L-xylono-1,4-lactone + H(+) + NADPH. GO:0050038 L-xylulose reductase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050038 KEGG_REACTION:R01904|EC:1.1.1.10|Reactome:R-HSA-5661240|Reactome:R-HSA-5662851|RHEA:17025|MetaCyc:L-XYLULOSE-REDUCTASE-RXN L-xylulose reductase activity Catalysis of the reaction: NADP(+) + xylitol = L-xylulose + H(+) + NADPH. GO:0050035 L-sorbose oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050035 EC:1.1.3.11|KEGG_REACTION:R01695|RHEA:17853|MetaCyc:L-SORBOSE-OXIDASE-RXN L-sorbose:oxygen 5-oxidoreductase activity Catalysis of the reaction: L-sorbose + O(2) = 5-dehydro-D-fructose + H(2)O(2). GO:0050036 L-threonate 3-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050036 KEGG_REACTION:R03733|RHEA:23376|EC:1.1.1.129|MetaCyc:L-THREONATE-3-DEHYDROGENASE-RXN threonate dehydrogenase activity|L-threonate:NAD+ 3-oxidoreductase activity|L-threonic acid dehydrogenase activity Catalysis of the reaction: L-threonate + NAD(+) = 3-dehydro-L-threonate + H(+) + NADH. CHEBI:27247 urocanate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27247 CHEBI:27248 urocanic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27248 GO:0050039 lactaldehyde reductase (NADPH) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050039 EC:1.1.1.55|KEGG_REACTION:R02259|RHEA:15885|MetaCyc:LACTALDEHYDE-REDUCTASE-NADPH-RXN propane-1,2-diol:NADP+ oxidoreductase activity|1,2-propanediol:NADP+ oxidoreductase activity|lactaldehyde (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|NADP-1,2-propanediol dehydrogenase activity|propanediol dehydrogenase activity Catalysis of the reaction: NADP(+) + propane-1,2-diol = (S)-lactaldehyde + H(+) + NADPH. GO:0015708 silicic acid import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015708 silicic acid transport|silicon uptake|silicic acid import|silicate transport The directed movement of silicates from outside of a cell, across the plasma membrane and into the cytosol. Silicates are the salts of silicic acids, and are usually composed of silicon and oxygen (Si[x]O[y]), one or more metals, and possibly hydrogen. Types of silicate include unisilicates, metasilicates and hydrous silicates. CL:0000776 immature neutrophil biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000776 immature neutrophil leucocyte|immature neutrocyte|immature neutrophilic leucocyte|immatuer neutrophilic leukocyte|immature neutrophil leukocyte Any of the immature forms of a neutrophil in which neutrophilic specific granules are present but other phenotypic features of the mature form may be lacking. GO:0015709 thiosulfate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015709 thiosulphate transport The directed movement of thiosulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CL:0000777 mesangial phagocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000777 mesangial cell A tissue-resident macrophage of the renal glomerular mesangium involved in the disposal and degradation of filtration residues, presentation of antigen to T cells and in tissue remodeling. CL:0000778 mononuclear osteoclast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000778 A specialized mononuclear osteoclast associated with the absorption and removal of bone, precursor of multinuclear osteoclasts. CL:0000779 multinuclear osteoclast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000779 multinucleated osteoclast A specialized multinuclear osteoclast associated with the absorption and removal of bone. GO:0015704 cyanate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015704 The directed movement of cyanate, NCO-, the anion of cyanic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015705 iodide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015705 The directed movement of iodide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UBERON:0010411 retroperitoneal fat pad biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010411 retroperitoneal fat depot encapsulated adipose tissue found on the dorsal side of the peritoneum GO:0015706 nitrate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015706 low-affinity nitrate transport|low affinity nitrate transport The directed movement of nitrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:27242 uridines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27242 GO:0015707 nitrite transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015707 The directed movement of nitrite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015700 arsenite transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015700 The directed movement of arsenite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015701 bicarbonate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015701 The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015702 chlorate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015702 The directed movement of chlorate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CL:0000770 band form basophil biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000770 A late basophilic metamyelocyte in which the nucleus is in the form of a curved or coiled band, not having acquired the typical multilobar shape of the mature basophil. CL:0000771 eosinophil biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000771 polymorphonuclear leucocyte|polymorphonuclear leukocyte|eosinocyte|eosinophilic leucocyte|eosinophilic granulocyte|eosinophilic leukocyte Any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. Eosinophils are CD9-positive, CD191-positive, and CD193-positive. GO:0015703 chromate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015703 The directed movement of chromate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CL:0000772 immature eosinophil biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000772 immature eosinophilic leucocyte|immature eosinophilic leukocyte|immature eosinocyte Any of the immature forms of an eosinophil, in which eosinophilic specific granules are present but other phenotypic features of the mature form may be lacking. CHEBI:17899 7alpha-hydroxycholest-4-en-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17899 CL:0000773 eosinophilic metamyelocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000773 A eosinophil precursor in the granulocytic series, being a cell intermediate in development between a eosinophilic myelocyte and a band form eosinophil. The nucleus becomes indented where the indentation is smaller than half the distance to the farthest nuclear margin; chromatin becomes coarse and clumped; specific granules predominate while primary granules are rare. Markers are integrin alpha-M-positive, fucosyltransferase FUT4-positive, low affinity immunoglobulin gamma Fc region receptor III-positive, CD33-positive, CD24-positive and aminopeptidase N-negative. CL:0000774 band form eosinophil biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000774 A late eosinophilic metamyelocyte in which the nucleus is in the form of a curved or coiled band, not having acquired the typical multilobar shape of the mature eosinophil. CHEBI:17897 L-rhamnulose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17897 CL:0000775 neutrophil biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000775 neutrocyte|polymorphonuclear leucocyte|neutrophilic leucocyte|neutrophil leukocyte|polynuclear neutrophilic leucocyte|polymorphonuclear neutrophil|neutrophilic leukocyte|polymorphonuclear leukocyte|polynuclear neutrophilic leukocyte|PMN|poly|neutrophil leucocyte Any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes. CHEBI:17898 all-trans-retinal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17898 CHEBI:17895 L-tyrosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17895 GO:0050030 L-pipecolate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050030 MetaCyc:L-PIPECOLATE-DEHYDROGENASE-RXN|RHEA:19777|EC:1.5.99.3 L-pipecolate:(acceptor) 1,6-oxidoreductase activity|L-pipecolate:acceptor 1,6-oxidoreductase activity Catalysis of the reaction: L-pipecolate + acceptor = delta1-piperideine-6-carboxylate + reduced acceptor. Delta1-piperideine-6-carboxylate is also known as 2,3,4,5-tetrahydropyridine-2-carboxylate. UBERON:0010409 ocular surface region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010409 ocular surface|eye surface|eye surface region The integrated unit (of the eye) that consists of the conjunctiva, the corneal surface, and the ocular mucosal adnexa including the lid margins and the meibomian gland openings, the lacrimal glands and the lacrimal drainage system, all which are critical to maintain ocular surface integrity and provide protection from external antigens and pathogenic microorganisms. CHEBI:17893 (2R)-2-hydroxy monocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17893 GO:0050033 L-rhamnono-1,4-lactonase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050033 MetaCyc:L-RHAMNONO-14-LACTONASE-RXN|EC:3.1.1.65|RHEA:10288|KEGG_REACTION:R03772 L-rhamno-gamma-lactonase activity|L-rhamnono-gamma-lactonase activity|L-rhamnono-1,4-lactone lactonohydrolase activity Catalysis of the reaction: L-rhamnono-1,4-lactone + H(2)O = L-rhamnonate + H(+). CHEBI:17891 donor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17891 GO:0050034 L-rhamnose 1-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050034 RHEA:12649|KEGG_REACTION:R03942|MetaCyc:L-RHAMNOSE-1-DEHYDROGENASE-RXN|EC:1.1.1.173 L-rhamnofuranose:NAD+ 1-oxidoreductase activity Catalysis of the reaction: L-rhamnofuranose + NAD(+) = L-rhamnono-1,4-lactone + H(+) + NADH. CHEBI:17892 L-rhamnulose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17892 GO:0050031 L-pipecolate oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050031 MetaCyc:L-PIPECOLATE-OXIDASE-RXN|KEGG_REACTION:R02204|EC:1.5.3.7|RHEA:11992|Reactome:R-HSA-6783880 L-pipecolic acid oxidase activity|L-pipecolate:oxygen 1,6-oxidoreductase activity Catalysis of the reaction: L-pipecolate + O(2) = 2,3,4,5-tetrahydropyridine-2-carboxylate + H(2)O(2) + H(+). Delta1-piperideine-6-carboxylate is also known as 2,3,4,5-tetrahydropyridine-2-carboxylate. CHEBI:17890 tryptophol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17890 GO:0050032 L-rhamnonate dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050032 KEGG_REACTION:R03774|MetaCyc:L-RHAMNONATE-DEHYDRATASE-RXN|EC:4.2.1.90|RHEA:23080 L-rhamnonate hydro-lyase (2-dehydro-3-deoxy-L-rhamnonate-forming)|L-rhamnonate hydro-lyase activity Catalysis of the reaction: L-rhamnonate = 2-dehydro-3-deoxy-L-rhamnonate + H(2)O. GO:0050048 L-leucine:2-oxoglutarate aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050048 RHEA:18321|MetaCyc:LEUCINE-AMINOTRANSFERASE-RXN|EC:2.6.1.6 leucine-alpha-ketoglutarate transaminase activity|L-leucine aminotransferase activity|leucine aminotransferase activity|leucine 2-oxoglutarate transaminase activity|leucine transaminase activity Catalysis of the reaction: L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate. GO:0050049 leucine dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050049 MetaCyc:LEUCINE-DEHYDROGENASE-RXN|RHEA:12220|EC:1.4.1.9 L-leucine:NAD+ oxidoreductase, deaminating|LeuDH activity|L-leucine:NAD+ oxidoreductase (deaminating)|L-leucine dehydrogenase activity Catalysis of the reaction: L-leucine + H2O + NAD+ = 4-methyl-2-oxopentanoate + NH3 + NADH. GO:0050046 lathosterol oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050046 MetaCyc:1.14.21.6-RXN|EC:1.14.21.6|RHEA:46556 delta7-sterol-C5(6)-desaturase activity|delta7-sterol delta5-dehydrogenase activity|5alpha-cholest-7-en-3beta-ol, NAD(P)H:oxygen 5-oxidoreductase activity|delta7-sterol 5-desaturase activity|5-DES|lathosterol 5-desaturase activity Catalysis of the reaction: 5-alpha-cholest-7-en-3-beta-ol + O2 = cholesta-5,7-dien-3-beta-ol + H2O2. GO:0050047 leucine 2,3-aminomutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050047 KEGG_REACTION:R01091|MetaCyc:LEUCINE-23-AMINOMUTASE-RXN|EC:5.4.3.7|RHEA:10284 (2S)-alpha-leucine 2,3-aminomutase activity Catalysis of the reaction: L-leucine = (3R)-beta-leucine. CHEBI:27216 urate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27216 CL:0000746 cardiac muscle cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000746 cardiocyte|cardiac myocyte|cardiac muscle fiber|heart muscle cell|cardiomyocyte Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. In mammals, the contractile fiber resembles those of skeletal muscle but are only one third as large in diameter, are richer in sarcoplasm, and contain centrally located instead of peripheral nuclei. CL:0000747 cyanophore biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000747 blue chromatophore A pigment cell derived from the neural crest. Contains blue pigment of unknown chemical composition in fibrous organelles termed cyanosomes. This gives a blue appearance. UBERON:0010400 spleen trabecular vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010400 trabecular vein one of the veins that feed the splenic vein CL:0000748 retinal bipolar neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000748 A bipolar neuron found in the retina and having connections with photoreceptors cells and neurons in the inner plexiform layer. CL:0000740 retinal ganglion cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000740 RGC|gangliocyte|ganglion cell of retina The set of neurons that receives neural inputs via bipolar, horizontal and amacrine cells. The axons of these cells make up the optic nerve. GO:0050040 lactate 2-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050040 MetaCyc:LACTATE-2-MONOOXYGENASE-RXN|EC:1.13.12.4|KEGG_REACTION:R00319|RHEA:16513 lactate oxygenase activity|lactic oxidase activity|(S)-lactate:oxygen 2-oxidoreductase (decarboxylating)|lactic oxygenase activity|L-lactate-2-monooxygenase activity|lactate oxidative decarboxylase activity|L-lactate monooxygenase activity|lactate oxidase activity|lactate monooxygenase activity Catalysis of the reaction: (S)-lactate + O(2) = acetate + CO(2) + H(2)O. GO:0050041 lactate aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050041 RHEA:17909|EC:4.1.2.36|KEGG_REACTION:R00753|MetaCyc:LACTATE-ALDOLASE-RXN lactate synthase activity|(S)-lactate acetaldehyde-lyase activity|(S)-lactate acetaldehyde-lyase (formate-forming) Catalysis of the reaction: (S)-lactate = acetaldehyde + formate. GO:0050044 galactose-6-phosphate isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050044 EC:5.3.1.26|MetaCyc:LACTOSE-6-PHOSPHATE-ISOMERASE-RXN|RHEA:13033|KEGG_REACTION:R03240 D-galactose-6-phosphate aldose-ketose-isomerase activity|D-galactose-6-phosphate ketol-isomerase activity Catalysis of the reaction: D-galactose 6-phosphate = D-tagatose 6-phosphate. GO:0050045 laminaribiose phosphorylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050045 MetaCyc:LAMINARIBIOSE-PHOSPHORYLASE-RXN|RHEA:16617|EC:2.4.1.31 3-beta-D-glucosyl-D-glucose:phosphate alpha-D-glucosyltransferase activity Catalysis of the reaction: 3-beta-D-glucosyl-D-glucose + phosphate = D-glucose + alpha-D-glucose 1-phosphate. GO:0050042 lactate-malate transhydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050042 EC:1.1.99.7|KEGG_REACTION:R01447|RHEA:10984|MetaCyc:LACTATE-MALATE-TRANSHYDROGENASE-RXN (S)-lactate:oxaloacetate oxidoreductase activity|malate-lactate transhydrogenase activity Catalysis of the reaction: (S)-lactate + oxaloacetate = malate + pyruvate. GO:0050043 lactate racemase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050043 EC:5.1.2.1|RHEA:10960|KEGG_REACTION:R01450|MetaCyc:LACTATE-RACEMASE-RXN lactic acid racemase activity|lacticoracemase activity|hydroxyacid racemase activity Catalysis of the reaction: (S)-lactate = (R)-lactate. GO:0050059 lombricine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050059 MetaCyc:LOMBRICINE-KINASE-RXN|EC:2.7.3.5|RHEA:23292 ATP:lombricine N-phosphotransferase activity Catalysis of the reaction: ATP + lombricine = ADP + N-phospholombricine. GO:0050057 linamarin synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050057 RHEA:20009|EC:2.4.1.63|MetaCyc:LINAMARIN-SYNTHASE-RXN UDP-glucose:2-hydroxy-2-methylpropanenitrile beta-D-glucosyltransferase activity|UDPglucose:2-hydroxy-2-methylpropanenitrile beta-D-glucosyltransferase activity|uridine diphosphoglucose-ketone glucosyltransferase activity|UDP glucose ketone cyanohydrin glucosyltransferase activity|uridine diphosphoglucose-ketone cyanohydrin glucosyltransferase activity|UDPglucose:ketone cyanohydrin beta-glucosyltransferase activity|uridine diphosphate-glucose-ketone cyanohydrin beta-glucosyltransferase activity Catalysis of the reaction: UDP-glucose + 2-hydroxy-2-methylpropanenitrile = UDP + linamarin. GO:0050058 linoleate isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050058 KEGG_REACTION:R03627|EC:5.2.1.5|RHEA:17381|MetaCyc:LINOLEATE-ISOMERASE-RXN linoleic acid isomerase activity|linoleate delta12-cis-delta11-trans-isomerase activity Catalysis of the reaction: linoleate = 9-cis,11-trans-octadecadienoate. CHEBI:27226 uric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27226 CL:0000751 rod bipolar cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000751 A bipolar neuron found in the retina that is synapsed by rod photoreceptor cells but not by cone photoreceptor cells. These neurons depolarize in response to light. CL:0000752 cone retinal bipolar cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000752 A bipolar neuron found in the retina and having connections with cone photoreceptor cells and neurons in the inner plexiform layer. GO:0050051 leukotriene-B4 20-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050051 MetaCyc:LEUKOTRIENE-B4-20-MONOOXYGENASE-RXN|RHEA:22176|Reactome:R-HSA-211873|EC:1.14.14.94 leukotriene-B4 omega-hydroxylase activity|leukotriene-B4 20-hydroxylase activity|LTB(4) 20-hydroxylase activity|LTB4 omega-hydroxylase activity|LTB(4) omega-hydroxylase activity|LTB4 20-hydroxylase activity Catalysis of the reaction: (6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate + NADPH + H+ + O2 = (6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + NADP+ + H2O. GO:0050052 leukotriene-E4 20-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050052 MetaCyc:LEUKOTRIENE-E4-20-MONOOXYGENASE-RXN|KEGG_REACTION:R04256|RHEA:24120|EC:1.14.13.34 (7E,9E,11Z,14Z)-(5S,6R)-6-(cystein-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate,NADPH:oxygen oxidoreductase (20-hydroxylating)|leukotriene-E4 omega-hydroxylase activity|leukotriene-E4 w-hydroxylase activity|leukotriene-E(4) omega-hydroxylase activity Catalysis of the reaction: H(+) + leukotriene E(4) + NADPH + O(2) = 20-hydroxy-leukotriene E(4) + H(2)O + NADP(+). GO:0050050 leucine N-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050050 EC:2.3.1.66|RHEA:20089|KEGG_REACTION:R01089|MetaCyc:LEUCINE-N-ACETYLTRANSFERASE-RXN leucine acetyltransferase activity|acetyl-CoA:L-leucine N-acetyltransferase activity Catalysis of the reaction: L-leucine + acetyl-CoA = N-acetyl-L-leucine + CoA + H(+). GO:0050055 limonin-D-ring-lactonase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050055 RHEA:10896|MetaCyc:LIMONIN-D-RING-LACTONASE-RXN|EC:3.1.1.36 limonin-D-ring-lactone hydrolase activity|limonoate-D-ring-lactone lactonohydrolase activity|limonin lactone hydrolase activity Catalysis of the reaction: limonoate D-ring-lactone + H2O = limonoate. GO:0050056 linalool 8-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050056 RHEA:20760|MetaCyc:LINALOOL-8-MONOOXYGENASE-RXN|KEGG_REACTION:R04366|EC:1.14.99.28 3,7-dimethylocta-1,6-dien-3-ol,hydrogen-donor:oxygen oxidoreductase (8-hydroxylating) Catalysis of the reaction: AH(2) + linalool + O(2) = (2E)-2,6-dimethylocta-2,7-diene-1,6-diol + A + H(2)O. GO:0050053 levansucrase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050053 EC:2.4.1.10|RHEA:13653|MetaCyc:LEVANSUCRASE-RXN sucrose 6-fructosyltransferase activity|sucrose:2,6-beta-D-fructan 6-beta-D-fructosyltransferase activity|beta-2,6-fructosyltransferase activity|beta-2,6-fructan:D-glucose 1-fructosyltransferase activity|sucrose 6-fructosyl transferase activity Catalysis of the reaction: sucrose + 2,6-beta-D-fructosyl(n) = glucose + 2,6-beta-D-fructosyl(n+1). GO:0050054 lignostilbene alpha beta-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050054 MetaCyc:LIGNOSTILBENE-ALPHA-BETA-DIOXYGENASE-RXN|KEGG_REACTION:R00043|RHEA:21340|EC:1.13.11.43 lignostilbene alphabeta-dioxygenase activity|1,2-bis(4-hydroxy-3-methoxyphenyl)ethylene:oxygen oxidoreductase (alphabeta-bond-cleaving)|lignostilbene ab-dioxygenase activity Catalysis of the reaction: 1,2-bis(4-hydroxy-3-methoxyphenyl)ethylene + O(2) = 2 vanillin. GO:0098004 virus tail fiber assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098004 The aggregation, arrangement and bonding together of a set of components to form a virus tail fiber. GO:0098005 viral head-tail joining biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098005 phage head tail joining|virus head-tail joining Process by which virus heads and tails are attached to each other. GO:0050068 lysine carbamoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050068 RHEA:17121|MetaCyc:LYSINE-CARBAMOYLTRANSFERASE-RXN|KEGG_REACTION:R01396|EC:2.1.3.8 lysine transcarbamylase activity|carbamoyl-phosphate:L-lysine carbamoyltransferase activity Catalysis of the reaction: L-lysine + carbamoyl phosphate = L-homocitrulline + H(+) + phosphate. GO:0098002 receptor-mediated bacteriophage irreversible attachment to host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098002 phage irreversible adsorption|irreversible bacteriophage attachment, binding of host cell surface receptor The processes by which a bacteriophage initially commits to infection by binding the host receptor irreversibly. Disruption of the phage:cell complex at this step results in the loss of infective phage virions since the process is characterized by conformational changes of bacteriophage head and tail proteins and injection of bacteriophage proteins into the infected cell. GO:0050069 lysine dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050069 EC:1.4.1.15|MetaCyc:LYSINE-DEHYDROGENASE-RXN|RHEA:18505 L-lysine:NAD+ oxidoreductase (deaminating, cyclizing) Catalysis of the reaction: L-lysine + NAD+ = 1,2-didehydropiperidine-2-carboxylate + NH3 + NADH. GO:0098003 viral tail assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098003 virus tail assembly|bacteriophage tail assembly The aggregation, arrangement and bonding together of a set of components to form a virus tail. GO:0098001 receptor-mediated bacteriophage reversible attachment to host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098001 reversible bacteriophage attachment, binding of host cell surface receptor|phage reversible adsorption Process by which a bacteriophage, using its tail fibers, spikes or a baseplate component, initially recognizes and binds to its specific receptor on the host cell surface. This process is reversible and allows the release of a bacteriophage without affecting infection. UBERON:0009471 dorsum of tongue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009471 dorsum linguae|tongue dorsum|dorsal tongue The superior surface of the tongue divided by the sulcus terminalis into an anterior two-thirds, the presulcal part (pars presulcalis). and a posterior one-third, the postsulcal part (pars postsulcalis). CL:0000722 cystoblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000722 CL:0000723 somatic stem cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000723 A stem cell that can give rise to cell types of the body other than those of the germ-line. CL:0000724 heterocyst biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000724 A differentiated cell that functions as a site of nitrogen fixation under aerobic conditions. CL:0000725 nitrogen fixing cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000725 CL:0000726 chlamydospore biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000726 An asexual 1-celled spore (primarily for perennation, not dissemination). Originates endogenously and singly within part of a pre-existing cell by the contraction of the protoplast. Possesses an inner secondary and often thickened hyaline or brown wall, usually impregnated with hydrophobic material. CHEBI:17868 1-palmitoylglycerone 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17868 CHEBI:17869 6-hydroxyhexanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17869 CHEBI:17866 digallate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17866 CHEBI:17867 UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17867 CHEBI:17864 taurolithocholic acid sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17864 CHEBI:17865 4-methyl-2-oxopentanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17865 UBERON:0009472 axilla biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009472 axilla|regio axillaris|underarm|armpit|axillary region|axillary region|arm pit|oxter|axillae|armpits The axilla is the area directly under the joint where the forelimb connects to the shoulder. GO:0050062 long-chain-fatty-acyl-CoA reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050062 EC:1.2.1.50|RHEA:15437|MetaCyc:LONG-CHAIN-FATTY-ACYL-COA-REDUCTASE-RXN long-chain fatty acyl-CoA reductase activity|acyl coenzyme A reductase activity|long-chain fatty acyl CoA reductase activity|long-chain-aldehyde:NADP+ oxidoreductase (acyl-CoA-forming) Catalysis of the reaction: a long-chain aldehyde + CoA + NADP+ = a long-chain acyl-CoA + NADPH. CHEBI:17862 3-dehydrosphinganine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17862 GO:0050063 obsolete low-density-lipoprotein particle receptor kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050063 MetaCyc:2.7.11.29-RXN|EC:2.7.11.29 LDL receptor kinase activity|low-density-lipoprotein receptor kinase (phosphorylating) activity|low-density lipoprotein receptor kinase activity|low-density-lipoprotein kinase activity|low-density-lipoprotein receptor kinase activity|STK7|ATP:low-density-lipoprotein-L-serine O-phosphotransferase activity|ATP:low-density-lipoprotein receptor-L-serine O-phosphotransferase activity|[low-density lipoprotein receptor] kinase activity OBSOLETE. Catalysis of the reaction: ATP + low-density lipoprotein L-serine = ADP + low-density lipoprotein O-phospho-L-serine. CHEBI:17863 cellobiono-1,5-lactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17863 CHEBI:17860 6-phospho-2-dehydro-3-deoxy-D-galactonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17860 GO:0050060 long-chain-alcohol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050060 EC:1.1.1.192|RHEA:17977|MetaCyc:LONG-CHAIN-ALCOHOL-DEHYDROGENASE-RXN fatty alcohol oxidoreductase activity|long-chain-alcohol:NAD+ oxidoreductase activity|long-chain alcohol dehydrogenase activity Catalysis of the reaction: a long-chain alcohol + 2 NAD+ + H2O = a long-chain carboxylate + 2 NADH. GO:0050061 long-chain-aldehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050061 EC:1.2.1.48|UM-BBD_reactionID:r1404|RHEA:10652|MetaCyc:LONG-CHAIN-ALDEHYDE-DEHYDROGENASE-RXN long-chain-aldehyde:NAD+ oxidoreductase activity|long-chain aliphatic aldehyde dehydrogenase activity|fatty aldehyde:NAD+ oxidoreductase activity|long-chain fatty aldehyde dehydrogenase activity Catalysis of the reaction: a long-chain aldehyde + NAD+ = a long-chain carboxylate + NADH + H+. A long-chain aldehyde is one with more than 12 carbons. CHEBI:17861 4-chlorobenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17861 GO:0050066 lysine 2,3-aminomutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050066 RHEA:19177|MetaCyc:LYSINE-23-AMINOMUTASE-RXN|KEGG_REACTION:R00461|EC:5.4.3.2 L-lysine 2,3-aminomutase activity Catalysis of the reaction: L-lysine = (3S)-3,6-diaminohexanoate. GO:0098009 viral terminase, large subunit biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098009 virus terminase, large subunit The part of the viral terminase complex that contains the translocase and endonuclease activities and allows the translocation of the phage DNA into the procapsid. The large subunit usually assembles as a heterooligomer with the small subunit. GO:0050067 lysine 2-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050067 EC:1.13.12.2|KEGG_REACTION:R00449|MetaCyc:LYSINE-2-MONOOXYGENASE-RXN|RHEA:14601 L-lysine-2-monooxygenase activity|lysine monooxygenase activity|lysine oxygenase activity|L-lysine:oxygen 2-oxidoreductase (decarboxylating) Catalysis of the reaction: L-lysine + O(2) = 5-aminopentanamide + CO(2) + H(2)O. UBERON:0009477 associated mesenchyme of otic placode biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009477 Mesenchyme that is part of a otic placode. GO:0098006 viral DNA genome packaging, headful biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0098006 phage headful packaging The encapsulation of the viral genome within the capsid where DNA is packaged into the capsid until the capsid is full. GO:0050064 luteolin 7-O-glucuronosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050064 RHEA:10568|KEGG_REACTION:R03589|MetaCyc:LUTEOLIN-7-O-GLUCORONOSYLTRANSFERASE-RXN|EC:2.4.1.189 UDPglucuronate:luteolin 7-O-glucuronosyltransferase activity|UDP-glucuronate:luteolin 7-O-glucuronosyltransferase activity|luteolin 7-O-glucoronosyltransferase activity|uridine diphosphoglucuronate-luteolin 7-O-glucuronosyltransferase activity|LGT Catalysis of the reaction: luteolin + UDP-alpha-D-glucuronate = luteolin 7-O-beta-D-glucosiduronate + UDP. GO:0050065 lysine-pyruvate 6-transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050065 RHEA:19393|MetaCyc:LYSINE--PYRUVATE-6-AMINOTRANSFERASE-RXN|MetaCyc:PWY-5324|KEGG_REACTION:R00453|EC:2.6.1.71 Lys-AT|L-lysine:pyruvate aminotransferase activity|lysine--pyruvate 6-aminotransferase activity|lysine-pyruvate aminotransferase activity Catalysis of the reaction: L-lysine + pyruvate = L-alanine + L-allysine. UBERON:0009479 ectoderm of buccopharyngeal membrane biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009479 An ectoderm that is part of a buccopharyngeal membrane. GO:0098015 virus tail biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098015 viral tail|bacteriophage tail Part of the virion that may be used to recognize, attach and inject the viral genome and accessory proteins into the host cell. CHEBI:27207 univalent carboacyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27207 CHEBI:27208 unsaturated fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27208 GO:0050079 acetylenecarboxylate hydratase activity, producing 3-oxopropanoate biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050079 RHEA:17957|MetaCyc:MALONATE-SEMIALDEHYDE-DEHYDRATASE-RXN|EC:4.2.1.27 malonate-semialdehyde dehydratase activity|alkynoate hydratase activity|acetylenecarboxylate hydratase activity, producing malonate-semialdehyde|acetylenemonocarboxylate hydrase activity|3-oxopropanoate hydro-lyase (propynoate-forming)|acetylmonocarboxylic acid hydrase activity|3-oxopropanoate hydro-lyase activity|acetylenemonocarboxylate hydratase activity|acetylenecarboxylate hydratase activity Catalysis of the reaction: 3-oxopropanoate = propynoate + H2O. CL:0000733 lymph gland plasmatocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000733 CL:0000735 lymph gland hemocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000735 CL:0000736 embryonic gland hemocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000736 CL:0000737 striated muscle cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000737 Muscle cell which has as its direct parts myofilaments organized into sarcomeres. CL:0000738 leukocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000738 white blood cell|immune cell|leucocyte An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue. CHEBI:17859 glutaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17859 CHEBI:17857 4-methyl-5-(2-phosphonooxyethyl)thiazole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17857 CHEBI:17858 glutathione disulfide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17858 CHEBI:17855 triglyceride biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17855 GO:0050070 lysolecithin acylmutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050070 KEGG_REACTION:R03334|RHEA:24356|EC:5.4.1.1|MetaCyc:LYSOLECITHIN-ACYLMUTASE-RXN lysolecithin 2,3-acylmutase activity|lysolecithin migratase activity Catalysis of the reaction: 1-acyl-sn-glycero-3-phosphocholine = 2-acyl-sn-glycero-3-phosphocholine. CHEBI:17856 glucuronoxylan 4-O-methyl-D-glucuronate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17856 CHEBI:42820 guanidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_42820 CL:0000730 leading edge cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000730 A cell at the front of a migrating epithelial sheet. CHEBI:17853 S-acetylcysteamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17853 CL:0000731 urothelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000731 transitional epithelial cell of urinary bladder|urinary tract transitional epithelial cell|bladder transitional cell A cell of a layer of transitional epithelium in the wall of the bladder, ureter, and renal pelvis, external to the lamina propria. CHEBI:17854 cyclohexanone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17854 GO:0050073 macrolide 2'-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050073 MetaCyc:MACROLIDE-2-KINASE-RXN|EC:2.7.1.136|KEGG_REACTION:R03780|RHEA:18333 ATP:macrolide 2'-O-phosphotransferase activity Catalysis of the reaction: ATP + oleandomycin = ADP + 2 H(+) + oleandomycin 2'-O-phosphate. CHEBI:17852 homocitric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17852 GO:0050074 malate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050074 EC:6.2.1.9|MetaCyc:MALATE--COA-LIGASE-RXN|RHEA:26193 malate thiokinase activity|malyl coenzyme A synthetase activity|malate:CoA ligase (ADP-forming)|malyl-CoA synthetase activity Catalysis of the reaction: ATP + malate + CoA = ADP + phosphate + malyl-CoA. GO:0050071 lysyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050071 EC:2.3.2.3|MetaCyc:LYSYLTRANSFERASE-RXN|RHEA:10668 L-lysyl-tRNA:phosphatidylglycerol O3-lysyltransferase activity|L-lysyl-tRNA:phosphatidylglycerol 3-O-lysyltransferase activity Catalysis of the reaction: L-lysyl-tRNA + phosphatidylglycerol = tRNA + 3-phosphatidyl-1'-(3'-O-L-lysyl)glycerol. GO:0050072 m7G(5')pppN diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050072 EC:3.6.1.30|MetaCyc:M7G5PPPN-PYROPHOSPHATASE-RXN 7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase activity|m7G(5')pppN pyrophosphatase activity|M(7)G(5')pppN pyrophosphatase activity|decapase activity Catalysis of the reaction: 7-methylguanosine 5'-triphospho-5'-polynucleotide + H2O = 7-methylguanosine 5'-phosphate + polynucleotide. CHEBI:17850 beta-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3-(beta-N-acetylneuraminyl-2,6)-N-acetyl-D-galactosaminyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17850 GO:0098019 obsolete virus tail, major subunit biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098019 major tail protein OBSOLETE. The part of the viral tail that comprises the most common subunit type. GO:0050077 maleylpyruvate isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050077 EC:5.2.1.4|MetaCyc:MALEYLPYRUVATE-ISOMERASE-RXN|RHEA:17393 3-maleylpyruvate cis-trans-isomerase activity Catalysis of the reaction: 3-maleylpyruvate = 3-fumarylpyruvate. GO:0050078 malonate CoA-transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050078 KEGG_REACTION:R00743|RHEA:18817|MetaCyc:MALONATE-COA-TRANSFERASE-RXN|EC:2.8.3.3 malonate coenzyme A-transferase activity|acetyl-CoA:malonate CoA-transferase activity Catalysis of the reaction: acetyl-CoA + malonate = acetate + malonyl-CoA. GO:0098017 viral capsid, major subunit biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098017 major capsomere|major head protein The part of the viral capsid that comprises the most common capsomere type. For example, in a T=3 icosahedral capsid, which is composed of 12 pentameric and 20 hexameric capsomeres, the hexameric capsomeres are major subunits. GO:0050075 maleate hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050075 EC:4.2.1.31|RHEA:23692|MetaCyc:MALEATE-HYDRATASE-RXN|KEGG_REACTION:R02419 (R)-malate hydro-lyase (maleate-forming)|malease activity|D-malate hydro-lyase activity|(R)-malate hydro-lyase activity Catalysis of the reaction: (R)-malate = H(2)O + maleate. GO:0098018 viral capsid, minor subunit biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0098018 minor capsomere|minor head protein The part of the viral capsid that comprises the less common capsomere type. For example, in a T=3 icosahedral capsid, which is composed of 12 pentameric and 20 hexameric capsomeres, the pentameric capsomeres are minor subunits. GO:0050076 maleate isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050076 RHEA:13169|KEGG_REACTION:R01087|EC:5.2.1.1|MetaCyc:MALEATE-ISOMERASE-RXN maleate cis-trans-isomerase activity Catalysis of the reaction: maleate = fumarate. CL:0000707 R7 photoreceptor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000707 R7 cell CL:0000708 leptomeningeal cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000708 leptomemingeal cell Stromal cell that forms the internal covering of the vertebrate brain and produces ECM for this and the choroid plexus. CL:0000709 R8 photoreceptor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000709 R8 cell CHEBI:6041 (+)-isopiperitenone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_6041 CL:0000700 dopaminergic neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000700 dopaminergic cell A neuron that releases dopamine as a neurotransmitter. CL:0000704 endothelial tip cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000704 A specialized endothelial cell that senses extracellular signals and guides the directed growth of blood vessels. CHEBI:6039 isopimaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_6039 GO:0050080 malonyl-CoA decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050080 MetaCyc:MALONYL-COA-DECARBOXYLASE-RXN|EC:4.1.1.9|Reactome:R-HSA-977317|RHEA:18781 malonyl-CoA carboxy-lyase (acetyl-CoA-forming)|malonyl coenzyme A decarboxylase activity|malonyl-CoA carboxy-lyase activity Catalysis of the reaction: malonyl-CoA = acetyl-CoA + CO2. CHEBI:17888 6-phospho-beta-D-glucosyl-(1->4)-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17888 GO:0050081 maltose-6'-phosphate glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050081 RHEA:20421|EC:3.2.1.122|MetaCyc:MALTOSE-6-PHOSPHATE-GLUCOSIDASE-RXN phospho-alpha-glucosidase activity|maltose-6'-phosphate 6-phosphoglucohydrolase activity Catalysis of the reaction: H2O + maltose 6'-phosphate = D-glucose + D-glucose 6-phosphate. CHEBI:17889 isopyridoxal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17889 CHEBI:17886 D-tagaturonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17886 CHEBI:17884 N(2)-phenylacetyl-L-glutamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17884 GO:0050084 mannitol-1-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050084 EC:3.1.3.22|MetaCyc:MANNITOL-1-PHOSPHATASE-RXN|KEGG_REACTION:R02167|RHEA:19537 mannitol-1-phosphate phosphatase activity|D-mannitol-1-phosphate phosphohydrolase activity Catalysis of the reaction: D-mannitol 1-phosphate + H(2)O = D-mannitol + 2 H(+) + phosphate. GO:0050085 mannitol 2-dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050085 MetaCyc:MANNITOL-2-DEHYDROGENASE-NADP+-RXN|KEGG_REACTION:R00870|RHEA:16765|EC:1.1.1.138 NADP-dependent mannitol dehydrogenase activity|D-mannitol:NADP+ 2-oxidoreductase activity Catalysis of the reaction: D-mannitol + NADP(+) = D-fructose + H(+) + NADPH. CHEBI:17885 CDP-glycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17885 CHEBI:17882 UDP-N-acetylmuramic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17882 GO:0050082 maltose phosphorylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050082 RHEA:21116|MetaCyc:MALTOSE-PHOSPHORYLASE-RXN|EC:2.4.1.8 maltose:phosphate 1-beta-D-glucosyltransferase activity Catalysis of the reaction: maltose + phosphate = D-glucose + beta-D-glucose 1-phosphate. CHEBI:17883 hydrogen chloride biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17883 GO:0050083 malyl-CoA lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050083 MetaCyc:MALYL-COA-LYASE-RXN|RHEA:16629|EC:4.1.3.24 (3S)-3-carboxy-3-hydroxypropanoyl-CoA glyoxylate-lyase (acetyl-CoA-forming)|malyl-coenzyme A lyase activity|(3S)-3-carboxy-3-hydroxypropanoyl-CoA glyoxylate-lyase activity Catalysis of the reaction: (3S)-3-carboxy-3-hydroxypropanoyl-CoA = acetyl-CoA + glyoxylate. CHEBI:6032 isonicotinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_6032 GO:0050088 mannose-6-phosphate 6-reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050088 KEGG_REACTION:R01817|RHEA:14925|MetaCyc:MANNOSE-6-PHOSPHATE-6-REDUCTASE-RXN|EC:1.1.1.224 D-mannitol-1-phosphate:NADP+ 6-oxidoreductase activity|NADP-dependent mannose-6-P:mannitol-1-P oxidoreductase activity|NADPH-dependent M6P reductase activity|mannose-6-phosphate reductase activity|6-phosphomannose reductase activity|NADPH-dependent mannose 6-phosphate reductase activity|NADPH-mannose-6-P reductase activity Catalysis of the reaction: D-mannitol 1-phosphate + NADP(+) = D-mannose 6-phosphate + 3 H(+) + NADPH. CHEBI:42819 5-dehydro-4-deoxy-D-glucarate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_42819 CHEBI:17881 5-amino-4-chloro-2-(2-hydroxymuconoyl)pyridazin-3(2H)-one biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17881 GO:0050089 mannose isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050089 RHEA:22604|KEGG_REACTION:R00877|EC:5.3.1.7|MetaCyc:MANNOSE-ISOMERASE-RXN D-mannose aldose-ketose-isomerase activity|D-mannose isomerase activity|D-mannose ketol-isomerase activity Catalysis of the reaction: D-mannose = D-fructose. GO:0050086 mannitol 2-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050086 EC:1.1.1.67|MetaCyc:MANNITOL-2-DEHYDROGENASE-RXN|RHEA:12084 D-mannitol dehydrogenase activity|D-mannitol:NAD+ 2-oxidoreductase activity Catalysis of the reaction: D-mannitol + NAD+ = D-fructose + NADH. GO:0050087 mannitol dehydrogenase (cytochrome) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050087 RHEA:17597|MetaCyc:MANNITOL-DEHYDROGENASE-CYTOCHROME-RXN|EC:1.1.2.2 polyol dehydrogenase activity|D-mannitol:ferricytochrome-c 2-oxidoreductase activity Catalysis of the reaction: D-mannitol + ferricytochrome c = D-fructose + ferrocytochrome c. CL:0000718 compound eye cone cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000718 cone cell (sensu Endopterygota) CL:0000710 neurecto-epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000710 neuroepithelial cell Epithelial cells derived from neural plate and neural crest. CL:0000711 cumulus cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000711 Cumulus cell is a specialized granulosa cell that surrounds and nourishes the oocyte. This cell-type surrounds the fully-grown oocyte to form a cumulus-oocyte complex (abbr. COC). The terms cumulus oophorus cells, cumulus granulosa cells, cumulus oophorous granulosa cells, granulosa-cumulus cells are used to make a distinction between this cell and the other functionally different subpopulation of granulosa cells at the wall of the Graafian follicle. CL:0000715 embryonic crystal cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000715 CL:0000716 lymph gland crystal cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000716 UBERON:0010425 internal naris biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010425 internal choana|internal nostril|choana|internal nares|choanae A naris that is located inside the nasal cavity and connects to the pharynx. CHEBI:17879 4-hydroxybenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17879 CHEBI:17877 FADH2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17877 GO:0050091 melilotate 3-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050091 EC:1.14.13.4|KEGG_REACTION:R03369|MetaCyc:MELILOTATE-3-MONOOXYGENASE-RXN|RHEA:17669 3-(2-hydroxyphenyl)propanoate,NADH:oxygen oxidoreductase (3-hydroxylating)|melilotate hydroxylase activity|2-hydroxyphenylpropionic hydroxylase activity|melilotic hydroxylase activity|2-hydroxyphenylpropionate hydroxylase activity Catalysis of the reaction: 3-(2-hydroxyphenyl)propanoate + H(+) + NADH + O(2) = 3-(2,3-dihydroxyphenyl)propanoate + H(2)O + NAD(+). GO:0050092 meso-tartrate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050092 EC:1.3.1.7|RHEA:18553|MetaCyc:MESO-TARTRATE-DEHYDROGENASE-RXN|KEGG_REACTION:R02544 meso-tartrate:NAD+ oxidoreductase activity Catalysis of the reaction: (2R,3S)-tartrate + NAD(+) = dihydroxyfumarate + H(+) + NADH. CHEBI:17878 2-hydroxycyclohexan-1-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17878 UBERON:0010427 ciliary processes biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010427 processus ciliares|ciliary process|ciliary processes set|ciliary processes|set of ciliary processes|processus ciliares The ciliary processes are formed by the inward folding of the various layers of the choroid, i.e. , the choroid proper and the lamina basalis, and are received between corresponding foldings of the suspensory ligament of the lens. CHEBI:17875 quercetin 3,3'-bissulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17875 GO:0050090 mannuronate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050090 MetaCyc:MANNURONATE-REDUCTASE-RXN|EC:1.1.1.131 D-mannonate:nicotinamide adenine dinucleotide (phosphate oxidoreductase (D-mannuronate-forming))|mannonate dehydrogenase (NAD(P)+)|mannonate (nicotinamide adenine dinucleotide (phosphate))dehydrogenase activity|mannonate dehydrogenase activity|D-mannonate:NAD(P)+ 6-oxidoreductase activity Catalysis of the reaction: D-mannonate + NAD(P)+ = D-mannuronate + NAD(P)H + H+. UBERON:0010428 flat bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010428 os planum A bone that is shaped as a broad flat plate and composed of two thin layers of compact tissue enclosing between them a variable quantity of cancellous tissue, which is the location of red bone marrow. CHEBI:17876 rifamycin B biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17876 GO:0050095 methionine decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050095 RHEA:17757|EC:4.1.1.57|KEGG_REACTION:R00656|MetaCyc:METHIONINE-DECARBOXYLASE-RXN L-methionine carboxy-lyase (3-methylthiopropanamine-forming)|L-methionine carboxy-lyase activity|L-methionine decarboxylase activity Catalysis of the reaction: L-methionine + H(+) = 3-methylthiopropanamine + CO(2). GO:0050096 methylaspartate ammonia-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050096 KEGG_REACTION:R03696|EC:4.3.1.2|MetaCyc:METHYLASPARTATE-AMMONIA-LYASE-RXN|RHEA:12829 beta-methylaspartase activity|L-threo-3-methylaspartate ammonia-lyase (mesaconate-forming)|3-methylaspartase activity|L-threo-3-methylaspartate ammonia-lyase activity Catalysis of the reaction: threo-3-methyl-L-aspartate = mesaconate + NH(4)(+). CHEBI:17874 dihydrozeatin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17874 GO:0050093 methanol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050093 MetaCyc:METHANOL-DEHYDROGENASE-RXN|RHEA:19401|EC:1.1.1.244|KEGG_REACTION:R00605 methanol:NAD+ oxidoreductase activity Catalysis of the reaction: methanol + NAD(+) = formaldehyde + H(+) + NADH. CHEBI:17871 3-hydroxypropanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17871 GO:0050094 methionine-glyoxylate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050094 MetaCyc:METHIONINE--GLYOXYLATE-TRANSAMINASE-RXN|EC:2.6.1.73|KEGG_REACTION:R00652|RHEA:22884 MGAT activity|L-methionine:glyoxylate aminotransferase activity|methionine-glyoxylate aminotransferase activity Catalysis of the reaction: L-methionine + glyoxylate = 4-methylthio-2-oxobutanoate + glycine. CHEBI:17872 2-oxo-2H-pyran-4,6-dicarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17872 GO:0050099 methylglutamate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050099 RHEA:22572|KEGG_REACTION:R00609|EC:1.5.99.5|MetaCyc:METHYLGUTAMATE-DEHYDROGENASE-RXN N-methylglutamate dehydrogenase activity|N-methyl-L-glutamate:(acceptor) oxidoreductase (demethylating)|N-methyl-L-glutamate:acceptor oxidoreductase (demethylating) Catalysis of the reaction: N-methyl-L-glutamate + A + H(2)O = L-glutamate + AH(2) + formaldehyde. GO:0050097 methylaspartate mutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050097 KEGG_REACTION:R00262|MetaCyc:METHYLASPARTATE-MUTASE-RXN|EC:5.4.99.1|RHEA:12857 glutamic mutase activity|glutamate isomerase activity|beta-methylaspartate-glutamate mutase activity|glutamate mutase activity|L-threo-3-methylaspartate carboxy-aminomethylmutase activity|methylaspartic acid mutase activity|glutamic isomerase activity|b-methylaspartate-glutamate mutase activity|glutamic acid isomerase activity|glutamic acid mutase activity Catalysis of the reaction: threo-3-methyl-L-aspartate = L-glutamate. GO:0050098 methylguanidinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050098 RHEA:11764|MetaCyc:METHYLGUANIDINASE-RXN|EC:3.5.3.16|KEGG_REACTION:R01589 methylguanidine hydrolase activity|methylguanidine amidinohydrolase activity Catalysis of the reaction: H(2)O + methylguanidine = methylammonium + urea. GO:0001015 snoRNA transcription by RNA polymerase II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001015 snoRNA transcription from an RNA polymerase II promoter The synthesis of small nucleolar RNA (snoRNA) from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter. GO:0001016 RNA polymerase III transcription regulatory region sequence-specific DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001016 RNA polymerase III regulatory region DNA binding Interacting selectively and non-covalently with a DNA region that controls the transcription of a gene by RNA polymerase III. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors. GO:0001017 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001017 GO:0001018 mitochondrial promoter sequence-specific DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001018 mitochondrial RNA polymerase core promoter sequence-specific DNA binding|LSPas binding|mitochondrial proximal promoter sequence-specific DNA binding|mitochondrial RNA polymerase core promoter proximal region sequence-specific DNA binding|mitochondrial heavy strand promoter sense binding|HSPas binding|mitochondrial heavy strand promoter anti-sense binding|HSPs binding|LSPs binding|mitochondrial RNA polymerase regulatory region DNA binding|mitochondrial RNA polymerase regulatory region sequence-specific DNA binding|mitochondrial light strand promoter sense binding|LSP coding strand binding|LSP non-coding strand binding|mitochondrial light strand promoter anti-sense binding|HSP coding strand binding|HSP non-coding strand binding Interacting selectively and non-covalently with a DNA region that controls the transcription of the mitochondrial DNA. GO:0001011 obsolete transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001011 sequence-specific DNA binding RNA polymerase recruiting transcription factor activity OBSOLETE. Interacting selectively and non-covalently with a specific DNA sequence and recruiting RNA polymerase to the DNA in order to form the preinitiation complex (PIC). GO:0001012 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001012 GO:0001013 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001013 GO:0001014 snoRNA transcription by RNA polymerase III biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001014 snoRNA transcription from a type 2 RNA polymerase III promoter The synthesis of small nucleolar RNA (snoRNA) from a DNA template by RNA polymerase III, originating at a type 2 RNA polymerase III promoter. CHEBI:134309 4'-O-methylxanthohumol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134309 GO:0039629 T=219 icosahedral capsid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0039629 The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=219 symmetry. T=219 icosahedral capsid is composed of 12 pentameric and 2180 hexameric capsomeres for a total of 13140 capsid proteins. GO:0001010 RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001010 sequence-specific DNA binding transcription factor recruiting transcription factor activity|transcription factor activity, sequence-specific DNA-binding transcription factor recruiting|transcription factor activity, sequence-specific DNA binding transcription factor recruiting The function of binding to a specific DNA sequence and recruiting another transcription factor to the DNA in order to modulate transcription. The recruited factor may bind DNA directly, or may be colocalized via protein-protein interactions. CHEBI:134308 xanthogalenol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134308 GO:0015656 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015656 GO:0039623 T=25 icosahedral viral capsid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0039623 VZ:810 The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=25 symmetry. The T=25 capsid is composed of 12 pentameric and 240 hexameric capsomeres. GO:0039624 viral outer capsid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0039624 outer capsid The outer layer of a double or triple concentric icosahedral capsid. Outer capsids are part of reoviridae and cystoviridae virions. CHEBI:134302 desmethylxanthohumol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134302 GO:0015657 branched-chain amino acid:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015657 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: branched-chain amino acid(out) + cation(out) = branched-chain amino acid(in) + cation(in). GO:0039621 T=13 icosahedral viral capsid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0039621 VZ:260 The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=13 symmetry. The T=13 capsid is composed of 12 pentameric and 120 hexameric capsomeres. GO:0015658 branched-chain amino acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015658 Reactome:R-HSA-9672770 branched-chain aliphatic amino acid transmembrane transporter activity|leucine/valine/isoleucine permease activity|branched-chain aliphatic amino acid transporter activity|valine/tyrosine/tryptophan permease activity Enables the transfer of branched-chain amino acids from one side of a membrane to the other. Branched-chain amino acids are amino acids with a branched carbon skeleton without rings. GO:0039622 T=16 icosahedral viral capsid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0039622 VZ:807 The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=16 symmetry. The T=16 capsid is composed of 12 pentameric and 150 hexameric capsomeres. GO:0015659 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015659 GO:0039627 T=147 icosahedral capsid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0039627 The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=147 symmetry. T=147 icosahedral capsid is composed of 12 pentameric and 1460 hexameric capsomeres for a total of 8820 capsid proteins. GO:0015652 quaternary ammonium group:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015652 quaternary ammonium group:hydrogen symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: quaternary ammonium group(out) + H+(out) = quaternary ammonium group(in) + H+(in). GO:0039628 T=169 icosahedral viral capsid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0039628 T=169 icosahedral capsid The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=169 symmetry. T=169 icosahedral capsid is composed of 12 pentameric and 1680 hexameric capsomeres for a total of 10140 capsid proteins. GO:0015653 glycine betaine:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015653 glycine betaine:hydrogen symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine betaine(out) + H+(out) = glycine betaine(in) + H+(in). GO:0039625 viral inner capsid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0039625 inner capsid The inner layer of a double or triple concentric icosahedral capsid. Inner capsids are part of reoviridae and cystoviridae virions. GO:0015654 tellurite transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015654 tellurite uptake transmembrane transporter activity|tellurite-resistance uptake permease activity|tellurite-resistance uptake transmembrane transporter activity Enables the transfer of tellurite from one side of a membrane to the other. Tellurite is a salt of tellurous acid or an oxide of tellurium which occurs sparingly in tufts of white or yellowish crystals. GO:0015655 alanine:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015655 RHEA:29283 sodium:alanine symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: alanine(out) + Na+(out) = alanine(in) + Na+(in). GO:0039626 viral intermediate capsid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0039626 intermediate capsid The intermediate layer of a triple concentric icosahedral capsid. Intermediate capsids are part of reoviridae virions. CHEBI:6099 kaempferide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_6099 GO:0015650 lactate:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015650 lactate permease|lactate:proton porter activity|lactate:hydrogen porter activity|lactate:hydrogen symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lactate (out) + H+ (out) = lactate (in) + H+ (in). CHEBI:52157 organic heteroheptacyclic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52157 GO:0015651 quaternary ammonium group transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015651 quaternary ammonium compound transporter activity|quaternary amine transmembrane transporter activity Enables the transfer of quaternary ammonium groups from one side of a membrane to the other. Quaternary ammonium groups are any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups. GO:0001019 plastid promoter transcription regulatory region sequence-specific DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001019 Interacting selectively and non-covalently with a DNA region that controls the transcription of a region of DNA by a plastid RNA polymerase. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors. GO:0039620 T=7 icosahedral viral capsid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0039620 VZ:804 The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=7 symmetry. The T=7 capsid is composed of 12 pentameric and 60 hexameric capsomeres. GO:0001026 obsolete TFIIIB-type transcription factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001026 RNA polymerase III recruiting transcription factor activity OBSOLETE. Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, Once recruited to an RNA polymerase III promoter by one or more other transcription factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex. GO:0001027 obsolete RNA polymerase III type 1 promoter TFIIIB-type transcription factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001027 RNA polymerase III type 1 promoter polymerase recruiting transcription factor activity OBSOLETE. Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III type 1 promoter by TFIIIA-type and TFIIIC-type factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex. GO:0001028 obsolete RNA polymerase III type 2 promoter TFIIIB-type transcription factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001028 RNA polymerase III type 2 promoter polymerase recruiting transcription factor activity OBSOLETE. Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III type 2 promoter by a TFIIIC-type factor, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex. GO:0001029 obsolete RNA polymerase III type 3 promoter TFIIIB-type transcription factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001029 RNA polymerase III type 3 promoter polymerase recruiting transcription factor activity OBSOLETE. Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III type 3 promoter by SNAP-type and TFIIIC-type factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex. GO:0001022 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001022 GO:0001023 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001023 GO:0001024 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001024 GO:0001025 RNA polymerase III general transcription initiation factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001025 RNA polymerase III transcription factor binding Interacting selectively and non-covalently with an RNA polymerase III transcription factor, any protein required to initiate or regulate transcription by RNA polymerase III. GO:0001020 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001020 GO:0039618 T=pseudo3 icosahedral viral capsid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0039618 VZ:809 The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with pseudo T=3 symmetry. The T=pseudo3 capsid is composed of 12 pentameric and 20 hexameric capsomeres. GO:0001021 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001021 GO:0039619 T=4 icosahedral viral capsid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0039619 VZ:808 The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=4 symmetry. The T=4 capsid is composed of 12 pentameric and 30 hexameric capsomeres. OIO:consider consider biolink:OntologyClass go-plus http://www.geneontology.org/formats/oboInOwl#consider GO:0015667 site-specific DNA-methyltransferase (cytosine-N4-specific) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015667 RHEA:16857|MetaCyc:2.1.1.113-RXN|EC:2.1.1.113 N4-cytosine-specific DNA methylase activity|S-adenosyl-L-methionine:DNA-cytosine N4-methyltransferase activity|S-adenosyl-L-methionine:DNA-cytosine 4-N-methyltransferase activity|N(4)-cytosine-specific DNA methylase activity|modification methylase activity|restriction-modification system activity|m4C-forming MTase activity|DNA[cytosine-N4]methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + DNA cytosine = S-adenosyl-L-homocysteine + DNA N4-methylcytosine. GO:0039612 modulation by virus of host protein phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039612 Any viral process that modulates the frequency, rate or extent of phosphorylation of viral or host proteins in a host. GO:0015668 type III site-specific deoxyribonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015668 EC:3.1.21.5|MetaCyc:3.1.21.5-RXN type III restriction enzyme activity Catalysis of the endonucleolytic cleavage of DNA to give double-stranded fragments with terminal 5'-phosphates. ATP hydrolysis is required. Cleavage is dependent on the presence of two copies of a specific recognition sequence in an inverse orientation in the DNA. Cleavage occurs at a specific distance from one of the recognition sites. GO:0039613 suppression by virus of host protein phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039613 viral inhibition of host protein phosphorylation Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of phosphorylation of viral or host proteins in a host. GO:0015669 gas transport biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0015669 The directed movement of substances that are gaseous in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0039611 suppression by virus of host translation initiation factor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039611 inhibition of activity of host translation initiation factor|Inhibition of host translation factors by virus|inactivation of eIF2 activity|suppression by virus of host EIF-4E activity Any process in which a virus prevents or reduces the frequency, rate or extent of activity of a host translation initiation factor. CHEBI:134311 D-altritol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134311 GO:0039616 T=2 icosahedral viral capsid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0039616 VZ:838 The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=2 symmetry. The T=2 capsid is composed of 12 pentameric dimers. GO:0015663 nicotinamide mononucleotide transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015663 nicotinamide ribonucleotide transmembrane transporter activity|nicotinamide mononucleotide permease activity Enables the directed movement of nicotinamide mononucleotide into, out of or within a cell, or between cells. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of d-ribose. It is a constituent of NAD and NADP. CHEBI:134316 2-acylphloroglucinol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134316 GO:0039617 T=3 icosahedral viral capsid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0039617 VZ:806 The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=3 symmetry. The T=3 capsid is composed of 12 pentameric and 20 hexameric capsomeres. GO:0015664 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015664 GO:0039614 induction by virus of host protein phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039614 Any process in which a virus activates or increases the frequency, rate or extent of phosphorylation of viral or host proteins in a host. GO:0015665 alcohol transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015665 Enables the transfer of an alcohol from one side of a membrane to the other. An alcohol is any carbon compound that contains a hydroxyl group. GO:0039615 T=1 icosahedral viral capsid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0039615 VZ:1057 The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=1 symmetry. The T=1 capsid is composed of 12 pentameric capsomeres. GO:0015666 restriction endodeoxyribonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015666 restriction endonuclease activity|restriction enzyme activity Catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks. CHEBI:52144 flavonol 7-O-beta-D-glucoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52144 GO:0015660 formate efflux transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015660 formate efflux permease activity Enables the transfer of formate from the inside of the cell to the outside of the cell across a membrane. GO:0015661 L-lysine efflux transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015661 L-lysine, 2,6-diaminohexanoic acid efflux transmembrane transporter activity|L-lysine exporter activity Enables the transfer of L-lysine from the inside of the cell to the outside of the cell across a membrane. GO:0015662 ion transmembrane transporter activity, phosphorylative mechanism biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015662 Reactome:R-HSA-429157 P-type ATPase activity|zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity|ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of ions across a membrane. The reaction is characterized by the transient formation of a high-energy aspartyl-phosphoryl-enzyme intermediate. CHEBI:52142 flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52142 CHEBI:52143 flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52143 PO:0004545 shoot-borne shoot system biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0004545 sucker (broad)|turion (broad)|シュート由来苗条系 (Japanese, exact)|sistema de epiblasto (epiblastema) que nace en el epiblasto (epiblastema) (Spanish, exact)|branch (related) A shoot system that is initiated from a shoot. CHEBI:52138 4-O-phosphohygromycin B biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52138 CHEBI:27177 L-tyrosine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27177 GO:0039607 obsolete proteolysis by virus of host translation initiation factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039607 cleavage of host translation initiation factor by virus|proteolytic cleavage by virus of host translation initiation factor|suppression by virus of host translation initiation factor activity by proteolysis|cleavage of host translation initiation factor by viral protease OBSOLETE. The chemical reactions and pathways performed by a virus resulting in the hydrolysis of a host translation initiation factor by cleavage of its peptide bonds. GO:0039608 obsolete suppression by virus of host translation initiation factor activity by induction of host protein dephosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039608 OBSOLETE. Any process in which a virus prevents or reduces the frequency, rate or extent of activity of a host translation initiation factor by promoting dephosphorylation of a host protein. GO:0015638 microcin transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015638 microcin uptake permease activity Enables the transfer of a microcin from one side of a membrane to the other. CHEBI:27173 typhasterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27173 GO:0015639 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015639 CHEBI:27175 tyramines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27175 GO:0015634 obsolete lipopolysaccharide exporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015634 LPS exporter activity OBSOLETE. Enables the transfer of lipopolysaccharide from the inside of the cell to the outside of the cell across a membrane. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide. GO:0039601 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0039601 GO:0015635 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015635 GO:0039602 suppression by virus of host transcription initiation from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039602 VZ:904 suppression by virus of host DNA-dependent transcription, initiation|inhibition of host transcription initiation by virus Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a host DNA template. GO:0015636 short-chain fatty acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015636 short-chain fatty acid transporter activity|short-chain fatty acid uptake transporter activity Enables the transfer of short-chain fatty acids from one side of a membrane to the other. Short-chain fatty acids are fatty acids with a chain length of less than C6. GO:0039600 induction by virus of host endonucleolytic cleavage-dependent mRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039600 induction by virus of host endonucleolytic cleavage-dependent mRNA decay|induction by virus of host nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay The process in which a virus increases the frequency, rate or extent of the breakdown of host nuclear-transcribed mRNAs that begins with endonucleolytic cleavage (by either a host or a viral RNAse) to generate unprotected ends. GO:0015637 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015637 GO:0015630 microtubule cytoskeleton biolink:CellularComponent go-plus goslim_aspergillus http://purl.obolibrary.org/obo/GO_0015630 The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins. GO:0039605 obsolete TFIIB-class transcription factor binding involved in viral suppression of host transcription initiation from RNA polymerase II promoter biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0039605 OBSOLETE. Selective and non-covalent interaction of a viral protein with a member of the TFIIB-class of host transcription factors, which contributes to the viral-suppression of assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a host DNA template. GO:0039606 suppression by virus of host translation initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039606 Any process in which a virus prevents or reduces the frequency, rate or extent of host translation initiation, the host process preceding formation of the peptide bond between the first two amino acids of a protein. GO:0015631 tubulin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015631 Interacting selectively and non-covalently with monomeric or multimeric forms of tubulin, including microtubules. GO:0039603 obsolete TBP-class protein binding involved in viral suppression of host transcription initiation from RNA polymerase II promoter biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0039603 OBSOLETE. Selective and non-covalent interaction of a viral protein with a member of the class of TATA-binding proteins (TBP) in the host, including any of the TBP-related factors (TRFs), which contributes to the viral-suppression of assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a host DNA template. GO:0015632 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015632 GO:0039604 suppression by virus of host translation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039604 VZ:1579 viral inhibition of cellular protein synthesis|host translation shutoff by virus|viral shutoff of host protein synthesis Any process in which a virus prevents or reduces the frequency, rate or extent of translation of host mRNA. GO:0015633 ABC-type zinc transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015633 EC:7.2.2.20|RHEA:29795 zinc transporting ATPase activity|zinc porter activity|ATP-dependent zinc transmembrane transporter activity|ATPase-coupled zinc transmembrane transporter activity|zinc-transporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Zn2+(out) = ADP + phosphate + Zn2+(in). CHEBI:52135 steroidal acyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52135 CHEBI:52136 glufosinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52136 CHEBI:52130 benzofuropyranochromene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52130 GO:0001004 obsolete RNA polymerase III transcription regulator recruiting activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001004 RNA polymerase III assembly factor activity, TFIIIB recruiting|TFIIIA activity|RNA polymerase III transcription factor recruiting activity|RNA polymerase III type 3 promoter TFIIIB recruiting transcription factor activity|transcription factor activity, RNA polymerase III promoter sequence-specific binding, TFIIIB recruiting|RNA polymerase III hybrid type promoter TFIIIB recruiting transcription factor activity|SNAPc-type activity|RNA polymerase III type 1 promoter sequence-specific DNA binding TFIIIB recruiting transcription factor activity|RNA polymerase III type 2 promoter sequence-specific DNA binding TFIIIB recruiting transcription factor activity|RNA polymerase III assembly factor activity|RNA polymerase III promoter sequence-specific DNA binding TFIIIB recruiting transcription factor activity|transcription factor activity, RNA polymerase III type 3 promoter TFIIIB recruiting|type 3 RNA polymerase III promoter recognition|transcription factor activity, RNA polymerase III type 2 promoter sequence-specific binding, TFIIIB recruiting|transcription factor activity, RNA polymerase III type 1 promoter sequence-specific binding, TFIIIB recruiting|type 2 RNA polymerase III promoter recognition|transcription factor activity, RNA polymerase III type 1 promoter TFIIIB|TFIIIC-type activity OBSOLETE. Initiating the assembly of the RNA polymerase III pre-initiation complex by binding to a control sequence in the intragenic region. This allows to recruit TFIIIB to the DNA at a site centered approximately 26 base pairs upstream of the start site of transcription. For tRNA genes, TFIIIC first associates with DNA, and then recruits TFIIIB. For 5S rRNA genes, TFIIIA binds to DNA first, followed by TFIIIC, which then recruits TFIIIB. PO:0004535 fruit placenta biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0004535 placenta del fruto (Spanish, exact)|果実の胎座 (Japanese, exact) A portion of placenta tissue (PO:0025078) that is part of a fruit (PO:0009001) and to which seeds (PO:0009010) are attached. GO:0001005 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001005 GO:0001006 RNA polymerase III type 3 promoter sequence-specific DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001006 RNA polymerase III type 3 promoter DNA binding Interacting selectively and non-covalently with a sequence of DNA that is a part of a type 3 promoter that controls transcription by RNA polymerase III (Pol III). A type 3 Pol III promoter is composed of elements upstream of the transcription start site, including a TATA box. The human U6 snRNA gene has a type 3 promoter. Type 3 Pol III promoters have not been observed in S. cerevisiae. GO:0001007 obsolete transcription factor activity, RNA polymerase III transcription factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001007 RNA polymerase III transcription factor binding transcription factor activity OBSOLETE. Interacting selectively and non-covalently with an RNA polymerase III transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. GO:0001000 bacterial-type RNA polymerase core enzyme binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001000 eubacterial-type RNA polymerase core enzyme binding Interacting selectively and non-covalently with the bacterial-type RNA polymerase core enzyme, typically consisting of two alpha, one beta, one beta prime, and one omega subunit. CHEBI:52127 (-)-glyceollin II biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52127 GO:0001001 mitochondrial single-subunit type RNA polymerase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001001 Interacting selectively and non-covalently with a single subunit mitochondrial RNA polymerase enzyme, which is composed of a single catalytic subunit similar to the RNA polymerase enzymes from phages T3, T7, and SP6. GO:0001002 RNA polymerase III type 1 promoter sequence-specific DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001002 RNA polymerase III type 1 promoter DNA binding Interacting selectively and non-covalently with a sequence of DNA that is a part of a type 1 promoter that controls transcription by RNA polymerase III. Type 1 promoters are found in 5S rRNA genes, downstream of the transcription start site within the sequence of the mature RNA, and require TFIIIA for recognition. GO:0001003 RNA polymerase III type 2 promoter sequence-specific DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001003 RNA polymerase III type 2 promoter DNA binding Interacting selectively and non-covalently with a sequence of DNA that is a part of a type 2 promoter that controls transcription by RNA polymerase III. Type 2 promoters consist of an A box and a B box downstream of the transcription start site within the sequence within the sequence of the mature RNA. Type 2 promoters are found in many tRNA genes as well as in other small RNAs. GO:0015649 2-keto-3-deoxygluconate:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015649 2-keto-3-deoxygluconate:hydrogen symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 2-keto-3-deoxygluconate(out) + H+(out) = 2-keto-3-deoxygluconate(in) + H+(in). GO:0015645 fatty acid ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015645 fatty acid CoA ligase activity|fatty-acid ligase activity|fatty acyl-coenzyme A synthetase activity Catalysis of the ligation of a fatty acid to an acceptor, coupled to the hydrolysis of ATP. CHEBI:27191 undecaprenols biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27191 GO:0015646 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015646 GO:0015647 peptidoglycan transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015647 murein transporter activity Enables the transfer of peptidoglycans, a class of glycoconjugates found in bacterial cell walls, from one side of a membrane to the other. CHEBI:27193 undecaprenyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27193 GO:0015648 lipid-linked peptidoglycan transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015648 lipid-linked murein transporter activity Enables the directed movement of lipid-linked peptidoglycans into, out of or within a cell, or between cells. CHEBI:27194 undecaprenyldiphospho-N-acetylmuramoyl peptide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27194 CHEBI:76151 (8Z,11Z,14Z)-heptadecatrienal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76151 GO:0015641 obsolete lipoprotein toxin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015641 lipoprotein toxin OBSOLETE. (Was not defined before being made obsolete). CHEBI:76152 (8Z,11Z,14Z)-heptadecatrienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76152 GO:0015642 obsolete bacteriolytic toxin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015642 bacteriolytic toxin activity OBSOLETE. Acts as to cause lysis of bacterial cells. GO:0015643 toxic substance binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015643 antitoxin activity|lipoprotein antitoxin Interacting selectively and non-covalently with a toxic substance, a poisonous substance that causes damage to biological systems. GO:0015644 obsolete lipoprotein antitoxin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015644 lipoprotein antitoxin OBSOLETE. Binds to a lipoprotein toxin, which is usually derived from a microorganism, thereby neutralizing it. CHEBI:76150 (R)-2-hydroxy-alpha-linolenate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76150 GO:0015640 peptidoglycan peptide transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015640 muropeptide transporter activity|murein peptide transporter activity Enables the transfer of peptidoglycan peptides from one side of a membrane to the other. Peptidoglycan peptides are the oligopeptides found in peptidoglycan networks which cross-link the polysaccharide chains. GO:0001008 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001008 CHEBI:76159 tetracenomycin F2(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76159 GO:0001009 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001009 GO:1990398 Cus cation efflux complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990398 IntAct:EBI-9010676 silver efflux system|Cus cation efflux system|silver efflux complex|copper efflux complex|copper efflux system Transmembrane complex that mediates resistance to copper and silver by cation efflux directly from the cell using the proton-motive force. Spans the inner membrane, periplasm, and outer membrane. Primarily activated under anaerobic conditions by CusR and CusS but also expressed under extreme copper stress, in aerobic growth. GO:1990399 epithelium regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990399 regeneration of epithelium The regrowth of lost or destroyed epithelium. GO:1990394 cellular response to cell wall damage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990394 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cell wall damage. The process begins with detection of the damage and ends with a change in state or activity of the cell. GO:1990395 meiotic spindle pole body organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990395 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the meiotic spindle pole body. GO:1990396 single-strand break repair via homologous recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990396 The error-free repair of a single-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule. GO:1990397 queuosine salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990397 Any process which produces queuosine from derivatives of it, without de novo synthesis. GO:1990390 protein K33-linked ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990390 A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 33 of the ubiquitin monomers, is added to a protein. GO:1990391 DNA repair complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990391 IntAct:EBI-16426962 WHY1 complex|DNA damage repair complex A protein complex involved in DNA repair processes including direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway. GO:1990392 EFF-1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990392 IntAct:EBI-9526622 A trimeric cell-cell fusion complex that serves as a scaffold for zippering up the extracellular domains, bringing the transmembrane segments into close proximity such that they can continue zippering within the two membranes into one. Two prefusion monomers cluster at the surface of adjacent cells. Parallel EFF-1 interactions occur across cells and a third monomer, which can come from either cell, adds on to make an intermediate, extended trimer. GO:1990393 3M complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990393 A protein complex, at least composed of CUL7, CCDC8 and OBSL1, that is required for maintaining microtubule and genome integrity. GO:0015616 DNA translocase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015616 Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive movement along a single- or double-stranded DNA molecule. GO:0015617 obsolete pilin/fimbrilin exporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015617 pilin/fimbrilin exporter activity OBSOLETE. (Was not defined before being made obsolete). CHEBI:27153 monoatomic trication biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27153 GO:0015618 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015618 GO:0015619 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015619 GO:0015612 ABC-type L-arabinose transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015612 MetaCyc:ABC-2-RXN|EC:7.5.2.13|EC:7.5.2.12|RHEA:30007 L-arabinose porter activity|L-arabinose-importing ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + L-arabinose(out) -> ADP + phosphate + L-arabinose(in). GO:0015613 obsolete galactose/glucose (methylgalactoside) porter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015613 galactose/glucose (methylgalactoside) porter activity OBSOLETE. (Was not defined before being made obsolete). GO:0015614 ABC-type D-xylose transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015614 RHEA:29902|EC:7.5.2.10 ATPase-coupled D-xylose transmembrane transporter activity|D-xylose-importing ATPase activity|D-xylose porter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-xylose(out) -> ADP + phosphate + D-xylose(in). GO:0015615 D-allose-importing ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015615 D-allose porter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-allose(out) -> ADP + phosphate + D-allose(in). GO:0015610 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015610 GO:0015611 ABC-type D-ribose transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015611 EC:7.5.2.8|RHEA:29903|MetaCyc:ABC-28-RXN D-ribose-importing ATPase activity|D-ribose porter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-ribose(out) -> ADP + phosphate + D-ribose(in). CHEBI:76161 (R)-2-hydroperoxy-alpha-linolenate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76161 CHEBI:76166 1,2-diacyl-3-O-[alpha-D-glucosyl-(1-> 2)-alpha-D-glucosyl]-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76166 CHEBI:76168 1-alkyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76168 GO:0015627 type II protein secretion system complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0015627 main terminal branch|MTB|general secretion pathway-associated complex|T2SS-associated complexes|Sec-dependent secretion system-associated complex A large protein complex, containing 12-15 subunits, that spans the cell envelope of Gram-negative bacteria and mediates the movement of proteins into the extracellular environment. The complex includes a component in the cytoplasm, an inner membrane subcomplex that reaches into the periplasmic compartment and a secretion pore in the outer membrane. Proteins using the Type II pathway are transported across the cytoplasmic membrane by the Sec or Tat complex. CHEBI:27162 tryptamines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27162 GO:0015628 protein secretion by the type II secretion system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015628 protein secretion by the T2S|protein secretion by the type II protein secretion system|protein secretion by the general secretory pathway|protein secretion by the general secretion pathway|protein secretion by the T2SS|type II protein secretion system The process in which proteins are secreted across the outer membrane of Gram-negative bacteria by the type II secretion system. Proteins using this pathway are first translocated across the cytoplasmic membrane via the Sec or Tat pathways. GO:0015629 actin cytoskeleton biolink:CellularComponent go-plus goslim_aspergillus http://purl.obolibrary.org/obo/GO_0015629 The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes. CHEBI:27164 tryptophan derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27164 GO:0015623 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015623 UBERON:0009503 mesenchyme of hindgut biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009503 hindgut associated mesenchyme Mesenchyme that is part of a developing hindgut. GO:0015624 ABC-type ferric-enterobactin transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015624 MetaCyc:ABC-10-RXN|EC:7.2.2.17|RHEA:58492 ferric-enterobactin-transporting ATPase activity|ferric-enterobactin ABC transporter|ferric-enterobactin porter activity|ATP-dependent ferric-enterobactin transmembrane transporter activity|ATPase-coupled ferric-enterobactin transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ferric-enterobactin(out) = ADP + phosphate + ferric-enterobactin(in). CHEBI:76170 olefinic phospholipid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76170 GO:0015625 ABC-type ferric hydroxamate transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015625 MetaCyc:3.6.3.34-RXN|MetaCyc:ABC-11-RXN|MetaCyc:ABC-9-RXN|EC:7.2.2.16 ferric-hydroxamate porter activity|ATPase-coupled ferric-hydroxamate transmembrane transporter activity|ATP-dependent iron-chelate transporter activity|ATPase-coupled iron-chelate transporter activity|ferric-hydroxamate-transporting ATPase activity|iron-chelate-transporting ATPase activity|ferric-hydroxamate transmembrane transporter activity|ferric-hydroxamate ABC transporter|ATP-dependent ferric-hydroxamate transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ferric-hydroxamate(out) = ADP + phosphate + ferric-hydroxamate(in). CHEBI:27171 organic heterobicyclic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27171 UBERON:0009505 mesenchyme of trachea biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009505 trachea associated mesenchyme Mesenchyme that is part of a developing trachea. GO:0015626 L-diaminopimelate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015626 L-diaminopimelate transporter activity|cystine/diaminopimelate porter activity Enables the transfer of L-diaminopimelate from one side of a membrane to the other. L-diaminopimelate is the L-enantiomer anion of 2,6-diaminoheptanedioic acid. UBERON:0009506 mesenchyme of middle ear biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009506 otic mesenchyme|middle ear associated mesenchyme Mesenchyme that is part of a developing middle ear. GO:0015620 ferric-enterobactin transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015620 Enables the transfer of ferric-enterobactin from one side of a membrane to the other. CHEBI:76171 1-acyl-2-(10-methylenealkanoyl)-sn-3-glycerophospholipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76171 GO:0015621 ferric triacetylfusarinine C transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015621 Enables the transfer of ferric triacetylfusarinine C from one side of a membrane to the other. GO:0015622 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015622 CHEBI:76177 (2R)-2-hydroxy fatty acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76177 CHEBI:76176 2-hydroxy fatty acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76176 UBERON:0009500 periotic mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009500 otocyst mesenchyme|periotic region|otocyst associated mesenchyme Anatomical region that surrounds the otic vesicle. CHEBI:76179 O-(S-acylpantetheine-4'-phosphoryl)serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76179 CHEBI:124959 (2S)-2-amino-5-[[amino(methylimino)methyl]amino]pentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_124959 UBERON:0009501 mesenchyme of fronto-nasal process biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009501 naso-frontal mesenchyme|frontonasal mesenchyme The embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the frontonasal region of the head GO:0050004 isoflavone 7-O-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050004 RHEA:56344|EC:2.4.1.170|MetaCyc:ISOFLAVONE-7-O-GLUCOSYLTRANSFERASE-RXN UDPglucose:isoflavone 7-O-beta-D-glucosyltransferase activity|UDPglucose-flavonoid 7-O-glucosyltransferase activity|UDPglucose:isoflavone 7-O-glucosyltransferase activity|uridine diphosphoglucose-isoflavone 7-O-glucosyltransferase activity|UDP-glucose:isoflavone 7-O-beta-D-glucosyltransferase activity Catalysis of the reaction: UDP-glucose + isoflavone = UDP + isoflavone 7-O-beta-D-glucoside. GO:0050005 isohexenylglutaconyl-CoA hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050005 RHEA:24144|KEGG_REACTION:R03493|MetaCyc:ISOHEXENYLGLUTACONYL-COA-HYDRATASE-RXN|EC:4.2.1.57|UM-BBD_reactionID:r1167 beta-isohexenylglutaconyl-CoA-hydratase activity|isohexenylglutaconyl coenzyme A hydratase activity|3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA hydro-lyase activity|3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA hydro-lyase [3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA-forming]|3-hydroxy-3-isohexenylglutaryl-CoA-hydrolase activity Catalysis of the reaction: 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA = 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + H(2)O. GO:0050002 D-proline reductase (dithiol) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050002 EC:1.21.4.1|MetaCyc:1.21.4.1-RXN|RHEA:12737 5-aminopentanoate:lipoate oxidoreductase (cyclizing) Catalysis of the reaction: lipoate + 5-aminopentanoate = dihydrolipoate + D-proline. GO:0050003 deoxycytidylate C-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050003 KEGG_REACTION:R01670|EC:2.1.1.54|MetaCyc:DEOXYCYTIDYLATE-C-METHYLTRANSFERASE-RXN|RHEA:11568 deoxycytidylate methyltransferase activity|5,10-methylenetetrahydrofolate:dCMP C-methyltransferase activity|dCMP methyltransferase activity Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dCMP = 2'-deoxy-5-methyl-5'-cytidylate + 7,8-dihydrofolate. GO:0050008 isopiperitenone delta-isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050008 EC:5.3.3.11|KEGG_REACTION:R03782|MetaCyc:ISOPIPERITENONE-DELTA-ISOMERASE-RXN|RHEA:21516 isopiperitenone D-isomerase activity|isopiperitenone delta8-delta4-isomerase activity Catalysis of the reaction: isopiperitenone = piperitenone. CHEBI:27137 triose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27137 GO:0050009 isopropanol dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050009 EC:1.1.1.80|KEGG_REACTION:R01550|RHEA:21792|MetaCyc:ISOPROPANOL-DEHYDROGENASE-NADP+-RXN propan-2-ol:NADP+ oxidoreductase activity Catalysis of the reaction: NADP(+) + propan-2-ol = acetone + H(+) + NADPH. GO:0050006 isomaltulose synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050006 RHEA:24032|MetaCyc:ISOMALTULOSE-SYNTHASE-RXN|EC:5.4.99.11 trehalulose synthase activity|isomaltulose synthetase activity|sucrose alpha-glucosyltransferase activity|sucrose glucosylmutase activity Catalysis of the reaction: sucrose = 6-O-alpha-D-glucopyranosyl-D-fructofuranose. GO:0050007 isonocardicin synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050007 RHEA:19845|KEGG_REACTION:R03072|MetaCyc:ISONOCARDICIN-SYNTHASE-RXN|EC:2.5.1.38 nocardicin aminocarboxypropyltransferase activity|S-adenosyl-L-methionine:nocardicin-E 3-amino-3-carboxypropyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine(1+) + nocardicin E = S-methyl-5'-thioadenosine + H(+) + isonocardicin A. CL:0000787 memory B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000787 memory B-lymphocyte|memory B lymphocyte|memory B-cell A memory B cell is a mature B cell that is long-lived, readily activated upon re-encounter of its antigenic determinant, and has been selected for expression of higher affinity immunoglobulin. This cell type has the phenotype CD19-positive, CD20-positive, MHC Class II-positive, and CD138-negative. CL:0000788 naive B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000788 naive B-cell|naive B-lymphocyte|naive B lymphocyte A naive B cell is a mature B cell that has the phenotype surface IgD-positive, surface IgM-positive, CD20-positive, CD27-negative and that has not yet been activated by antigen in the periphery. CHEBI:27134 trimethylxanthine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27134 CL:0000789 alpha-beta T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000789 alpha-beta T lymphocyte|alpha-beta T-cell|alpha-beta T-lymphocyte A T cell that expresses an alpha-beta T cell receptor complex. CHEBI:27135 trinitrotoluene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27135 CHEBI:27136 triol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27136 CHEBI:76180 arachidonoyl bioconjugate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76180 CL:0000780 multinuclear odontoclast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000780 multinucleated odontoclast A specialized multinuclear osteoclast associated with the absorption and removal of cementum. CL:0000781 mononuclear odontoclast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000781 A specialized mononuclear osteoclast associated with the absorption and removal of cementum. CL:0000782 myeloid dendritic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000782 veiled cell|CD11c+CD123- DC|interdigitating cell|mDC A dendritic cell of the myeloid lineage. CHEBI:76184 alpha-linolenoyl bioconjugate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76184 CL:0000784 plasmacytoid dendritic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000784 plasmacytoid T cell|T-associated plasma cell|IPC|interferon-producing cell|plasmacytoid monocyte|DC2|type 2 DC|lymphoid dendritic cell|pDC A dendritic cell type of distinct morphology, localization, and surface marker expression (CD123-positive) from other dendritic cell types and associated with early stage immune responses, particularly the release of physiologically abundant amounts of type I interferons in response to infection. CHEBI:76185 stearidonoyl bioconjugate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76185 CL:0000785 mature B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000785 mature B-cell|mature B-lymphocyte|mature B lymphocyte A B cell that is mature, having left the bone marrow. Initially, these cells are IgM-positive and IgD-positive, and they can be activated by antigen. CL:0000786 plasma cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000786 plasmacyte|effector B cell|plasma B cell|plasmocyte|effector B-cell|plasma B-cell A terminally differentiated, post-mitotic, antibody secreting cell of the B cell lineage with the phenotype CD138-positive, surface immunonoglobulin-negative, and MHC Class II-negative. Plasma cells are oval or round with extensive rough endoplasmic reticulum, a well-developed Golgi apparatus, and a round nucleus having a characteristic cartwheel heterochromatin pattern and are devoted to producing large amounts of immunoglobulin. CHEBI:76189 timnodonoyl bioconjugate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76189 CHEBI:76186 linoleoyl bioconjugate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76186 CHEBI:76187 gamma-linolenoyl bioconjugate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76187 GO:0050000 chromosome localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0050000 establishment and maintenance of chromosome position|chromosome localisation|establishment and maintenance of chromosome localization Any process in which a chromosome is transported to, or maintained in, a specific location. GO:0050001 D-glutaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050001 MetaCyc:D-GLUTAMINASE-RXN|EC:3.5.1.35|RHEA:22840 D-glutamine amidohydrolase activity Catalysis of the reaction: H2O + L-glutamine = NH3 + D-glutamate. GO:0050015 kievitone hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050015 RHEA:23604|KEGG_REACTION:R03622|EC:4.2.1.95|MetaCyc:KIEVITONE-HYDRATASE-RXN KHase activity|kievitone-hydrate hydro-lyase activity|kievitone-hydrate hydro-lyase (kievitone-forming) Catalysis of the reaction: kievitone hydrate = H(2)O + H(+) + kievitone. GO:0050016 kynurenine 7,8-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050016 EC:1.14.99.2|RHEA:11968|MetaCyc:KYNURENINE-78-HYDROXYLASE-RXN kynurenic acid hydroxylase activity|kynurenic hydroxylase activity|kynurenate 7,8-hydroxylase activity|kynurenate,hydrogen-donor:oxygen oxidoreductase (hydroxylating) Catalysis of the reaction: kynurenate + donor-H2 + O2 = 7,8-dihydro-7,8-dihydroxykynurenate + acceptor. GO:0050013 2-dehydropantoate aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050013 EC:4.1.2.12|MetaCyc:KETOPANTOALDOLASE-RXN|RHEA:23276 2-dehydropantoate formaldehyde-lyase (3-methyl-2-oxobutanoate-forming)|ketopantoaldolase activity|2-dehydropantoate formaldehyde-lyase activity Catalysis of the reaction: 2-dehydropantoate = 3-methyl-2-oxobutanoate + formaldehyde. GO:0050014 ketotetrose-phosphate aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050014 RHEA:20932|KEGG_REACTION:R01014|MetaCyc:KETOTETROSE-PHOSPHATE-ALDOLASE-RXN|EC:4.1.2.2 erythrulose-1-phosphate formaldehyde-lyase activity|erythrose-1-phosphate synthase activity|erythrulose-1-phosphate synthetase activity|phosphoketotetrose aldolase activity|erythrulose-1-phosphate formaldehyde-lyase (glycerone-phosphate-forming) Catalysis of the reaction: L-erythrulose 1-phosphate = formaldehyde + glycerone phosphate. GO:0050019 L-arabinitol 4-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050019 MetaCyc:L-ARABINITOL-4-DEHYDROGENASE-RXN|KEGG_REACTION:R01903|EC:1.1.1.12|RHEA:16381 Catalysis of the reaction: L-arabinitol + NAD(+) = L-xylulose + H(+) + NADH. GO:0050017 L-3-cyanoalanine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050017 MetaCyc:L-3-CYANOALANINE-SYNTHASE-RXN|EC:4.4.1.9|RHEA:17821 beta-cyanoalanine synthase activity|L-cysteine hydrogen-sulfide-lyase (adding HCN)|L-cysteine hydrogen-sulfide-lyase (adding hydrogen cyanide; L-3-cyanoalanine-forming)|beta-cyano-L-alanine synthase activity|beta-cyanoalanine synthetase activity Catalysis of the reaction: L-cysteine + HCN = sulfide + L-3-cyanoalanine. GO:0050018 L-amino-acid dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050018 RHEA:10396|EC:1.4.1.5|MetaCyc:L-AMINO-ACID-DEHYDROGENASE-RXN L-amino-acid:NAD+ oxidoreductase (deaminating) Catalysis of the reaction: an L-amino acid + H2O + NAD+ = a 2-oxo acid + NH3 + NADH. CL:0000798 gamma-delta T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000798 gamma-delta T lymphocyte|gd T cell|gamma-delta T-cell|gamma-delta T-lymphocyte|gammadelta T cell A T cell that expresses a gamma-delta T cell receptor complex. GO:0015609 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015609 CL:0000799 immature gamma-delta T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000799 immature gamma-delta T-lymphocyte|immature gamma-delta T lymphocyte|immature gamma-delta T-cell A gamma-delta T cell that has an immature phenotype. GO:0015605 organophosphate ester transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015605 Enables the transfer of organophosphate esters from one side of a membrane to the other. Organophosphate esters are small organic molecules containing phosphate ester bonds. GO:0015606 spermidine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015606 Enables the transfer of spermidine, N-(3-aminopropyl)-1,4-diaminobutane, from one side of a membrane to the other. GO:0015607 ABC-type fatty-acyl-CoA transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015607 RHEA:15181|EC:7.6.2.4 ABC-type fatty-acyl-CoA transporter|fatty-acyl-CoA-transporting ATPase|ATPase-coupled fatty-acyl-CoA transmembrane transporter activity|fatty acyl CoA transporter activity|fatty-acyl-CoA transmembrane transporter activity Catalysis of the reaction ATP + H(2)O + fatty acyl CoA(Side 1) <=> ADP + phosphate + fatty acyl CoA(Side 2). A fatty acyl CoA group is any acyl group derived from a fatty acid with a coenzyme A group attached to it. GO:0015608 carbohydrate-importing ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015608 sugar transporter|carbohydrate uptake transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carbohydrate(out) -> ADP + phosphate + carbohydrate(in). GO:0015601 obsolete cystine/diaminopimelate porter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015601 cystine/diaminopimelate porter activity OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + polar amino acid(out) = ADP + phosphate + polar amino acid(in). CL:0000790 immature alpha-beta T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000790 immature alpha-beta T-cell|immature alpha-beta T-lymphocyte|immature alpha-beta T lymphocyte An alpha-beta T cell that has an immature phenotype and has not completed T cell selection. CL:0000791 mature alpha-beta T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000791 mature alpha-beta T lymphocyte|mature alpha-beta T-cell|mature alpha-beta T-lymphocyte A alpha-beta T cell that has a mature phenotype. GO:0015602 obsolete leucine/isoleucine/valine porter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015602 leucine/isoleucine/valine porter activity OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + nonpolar amino acid(out) = ADP + phosphate + nonpolar amino acid(in). CL:0000792 CD4-positive, CD25-positive, alpha-beta regulatory T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000792 Treg|suppressor T-lymphocyte|CD4-positive, CD25-positive, alpha-beta regulatory T-cell|CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte|suppressor T cell|suppressor T lymphocyte|CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte|suppressor T-cell A CD4-positive, CD25-positive, alpha-beta T cell that regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release. GO:0015603 iron chelate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015603 Enables the transfer of an iron chelate from one side of a membrane to the other. An iron chelate is a heterocyclic compound having a metal ion attached by coordinate bonds to at least two nonmetal ions. GO:0015604 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015604 CL:0000793 CD4-positive, alpha-beta intraepithelial T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000793 CD4-positive, alpha-beta intraepithelial T lymphocyte|IEL|CD4-positive, alpha-beta intraepithelial T-cell|intraepithelial lymphocyte|CD4-positive, alpha-beta intraepithelial T-lymphocyte A CD4-positive, alpha-beta T cell that is found in the columnar epithelium of the gastrointestinal tract. CHEBI:27150 trisaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27150 CHEBI:76195 sapienoyl bioconjugate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76195 CL:0000794 CD8-positive, alpha-beta cytotoxic T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000794 killer T lymphocyte|CD8-positive, alpha-beta cytotoxic T-cell|CD8-positive, alpha-beta cytotoxic T-lymphocyte|cytotoxic T-cell|cytotoxic T-lymphocyte|killer T-cell|CD8-positive, alpha-beta cytotoxic T lymphocyte|killer T-lymphocyte|cytotoxic T cell|cytotoxic T lymphocyte|killer T cell A CD8-positive, alpha-beta T cell that is capable of killing target cells in an antigen specific manner with the phenotype perforin-positive and granzyme B-positive. CL:0000795 CD8-positive, alpha-beta regulatory T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000795 suppressor T-cell|CD8+ T(reg)|suppressor T-lymphocyte|CD8-positive, alpha-beta regulatory T lymphocyte|CD8-positive Treg|CD8+ Treg|suppressor T cell|CD8+ regulatory T cell|suppressor T lymphocyte|CD8-positive, alpha-beta regulatory T-cell|CD8-positive, alpha-beta regulatory T-lymphocyte|CD8-positive, alpha-beta Treg|CD8-positive T(reg) A CD8-positive, alpha-beta T cell that regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release. CL:0000796 CD8-alpha-beta-positive, alpha-beta intraepithelial T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000796 CD8-positive, alpha-beta intraepithelial T lymphocyte|IEL|CD8-positive, alpha-beta intraepithelial T-cell|CD8-positive, alpha-beta intraepithelial T-lymphocyte|intraepithelial lymphocyte A alpha-beta intraepithelial T cell found in the columnar epithelium of the gastrointestinal tract. Intraepithelial T cells often have distinct developmental pathways and activation requirements. GO:0015600 obsolete glutamate/aspartate porter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0015600 glutamate/aspartate porter activity OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + polar amino acid(out) = ADP + phosphate + polar amino acid(in). CHEBI:76194 palmitoyl bioconjugate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76194 CL:0000797 alpha-beta intraepithelial T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000797 alpha-beta intraepithelial T lymphocyte|IEL|alpha-beta intraepithelial T-cell|alpha-beta intraepithelial T-lymphocyte|intraepithelial lymphocyte A mature alpha-beta T cell of the columnar epithelium of the gastrointestinal tract. Intraepithelial T cells often have distinct developmental pathways and activation requirements. CHEBI:76197 sapienate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76197 GO:0050011 itaconyl-CoA hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050011 EC:4.2.1.56|RHEA:13785|MetaCyc:ITACONYL-COA-HYDRATASE-RXN citramalyl-CoA hydro-lyase activity|citramalyl-CoA hydro-lyase (itaconyl-CoA-forming)|itaconyl coenzyme A hydratase activity Catalysis of the reaction: citramalyl-CoA = itaconyl-CoA + H2O. GO:0050012 juglone 3-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050012 KEGG_REACTION:R04327|RHEA:18745|MetaCyc:JUGLONE-3-MONOOXYGENASE-RXN|EC:1.14.99.27 naphthoquinone hydroxylase activity|5-hydroxy-1,4-naphthoquinone,hydrogen-donor:oxygen oxidoreductase (3-hydroxylating)|naphthoquinone-hydroxylase activity|juglone hydroxylase activity Catalysis of the reaction: 5-hydroxy-1,4-naphthoquinone + AH(2) + O(2) = 3,5-dihydroxy-1,4-naphthoquinone + A + H(2)O + H(+). GO:0050010 isovitexin beta-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050010 RHEA:19529|KEGG_REACTION:R03686|EC:2.4.1.106|MetaCyc:ISOVITEXIN-BETA-GLUCOSYLTRANSFERASE-RXN UDP-glucose:isovitexin 2''-O-beta-D-glucosyltransferase activity|isovitexin b-glucosyltransferase activity|UDPglucose:isovitexin 2''-O-beta-D-glucosyltransferase activity|uridine diphosphoglucose-isovitexin 2''-glucosyltransferase activity Catalysis of the reaction: isovitexin + UDP-D-glucose = H(+) + isovitexin 2''-O-beta-D-glucoside + UDP. GO:1990354 activated SUMO-E1 ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990354 IntAct:EBI-9345927 SUMO-SAE1/2 complex A protein complex consisting of a SUMO protein bound to a SUMO activating enzyme complex. Activation by the E1 complex and linkage to the E2 enzyme UBE2I is required for the formation of covalent bonds between SUMO and its ultimate target proteins. GO:1990355 L-methionine salvage from methionine sulphoxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990355 methionine salvage from methionine sulphoxide The generation of L-methionine from methionine sulphoxide. GO:1990356 sumoylated E2 ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990356 IntAct:EBI-9347978 A protein complex consisting of a SUMO (small ubiquitin-related modifier) protein bound to a SUMO-conjugating E2 ligase. Sumoylation of the E2 ligase is an intermediate step required for the formation of covalent bonds between a SUMO protein and its ultimate protein target. SUMO is transferred to the E2 ligase by a SUMO-activating E1 enzyme. Sumoylation of the target protein is either facilitated directly by the sumoylated E2 ligase or aided by an optional E3 ligase. GO:1990357 terminal web biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990357 An actin-rich cytoskeletal network located beneath the microvilli of the apical plasma membrane of polarized epithelial cells. In addition to actin filaments, the terminal web may contain actin-binding proteins, myosin motor proteins, and intermediate filaments. The terminal web can function as a contractile structure that influences the spatial distribution of microvilli as well as the development and morphogenesis of tissues containing polarized epithelial cells. GO:1990350 glucose transporter complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990350 IntAct:EBI-960644|IntAct:EBI-960674|IntAct:EBI-959455 A protein complex facilitating glucose transport into, out of or within a cell, or between cells. GO:0001099 basal RNA polymerase II transcription machinery binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001099 basal RNAP II transcription machinery binding Interacting selectively and non-covalently with the basal transcription machinery for RNA polymerase II which is composed of the RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits, and the basal RNA polymerase II transcription factors, the minimal set of factors required for formation of the preinitiation complex (PIC) by the RNA polymerase. GO:1990351 transporter complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990351 A protein complex facilitating transport of molecules (proteins, small molecules, nucleic acids) into, out of or within a cell, or between cells. GO:1990352 BRE1 E3 ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990352 IntAct:EBI-9102292 BRE1 E3 ubiquitin-protein ligase complex|BRE1 oligomer A homodimeric protein complex composed of the E3 ubiquitin-protein ligase BRE1. Plays a role in regulating association of RNA polymerase II with active genes. GO:1990353 Fused-Smurf ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990353 IntAct:EBI-3405462 A ubiquitin ligase complex. In D. melanogaster, it regulates ubiquitination and proteolysis of the BMP receptor Thickveins in cystoblasts, potentially by controlling Tkv ubiquitination and degradation. GO:0001095 TFIIE-class transcription factor complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001095 TFIIE-class transcription factor binding Interacting selectively and non-covalently with a general RNA polymerase II transcription factor belonging to the TFIIE complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II. GO:0001096 TFIIF-class transcription factor complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001096 TFIIF-class transcription factor binding Interacting selectively and non-covalently with a general RNA polymerase II transcription factor belonging to the TFIIF complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II. NCBITaxon:119089 Chromadorea organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_119089 Adenophorea GO:0001097 TFIIH-class transcription factor complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001097 TFIIH-class transcription factor binding Interacting selectively and non-covalently with a general RNA polymerase II transcription factor belonging to the TFIIH complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II. GO:0001098 basal transcription machinery binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001098 Interacting selectively and non-covalently with the basal transcription machinery which is composed of the RNA polymerase core enzyme and the basal transcription factor(s), the minimal set of factors required for formation of the preinitiation complex (PIC) by the RNA polymerase. GO:0001091 RNA polymerase II general transcription initiation factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001091 RNA polymerase II basal transcription factor binding Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor, any of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II and defined as a basal or general transcription factor. GO:0001092 TFIIA-class transcription factor complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001092 TFIIA-class transcription factor binding Interacting selectively and non-covalently with a general RNA polymerase II transcription factor belonging to the TFIIA complex, one of the complexes involved in formation of the preinitiation complex (PIC) by RNA polymerase II and defined as a basal or general transcription factor. GO:0001093 TFIIB-class transcription factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001093 Interacting selectively and non-covalently with a general RNA polymerase II transcription factor of the TFIIB class, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II. GO:0001094 TFIID-class transcription factor complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001094 TFIID-class transcription factor binding Interacting selectively and non-covalently with a general RNA polymerase II transcription factor belonging to the TFIID complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II. CHEBI:134389 beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-D-Glcp biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134389 GO:1990358 xylanosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990358 xylanolytic complex A multifunctional supermolecular complex, containing several proteins with hemicellulase activity. Functions to hydrolyze hemicellulose. GO:1990359 stress response to zinc ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990359 stress response to zinc|response to zinc toxicity|response to zinc ion stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a zinc ion stimulus. CHEBI:134386 2-acylphloroglucinol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134386 GO:1990365 obsolete response to phenol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990365 response to phenol OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of phenols. GO:1990366 obsolete response to organic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990366 response to organic acid OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic acid. GO:1990367 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990367 GO:1990368 obsolete process resulting in tolerance to hydrolysate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990368 process resulting in tolerance to hydrolysate OBSOLETE. A response that results in a state of tolerance to hydrolysate (product of hydrolysis). GO:1990361 PKM2 pyruvate kinase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990361 PKM2 homotetramer A protein complex capable of pyruvate kinase activity. PKM2 only exists as homotetramer when bound to beta-d-fructofuranose 1,6-bisphosphate (CHEBI:28013). GO:1990362 butanol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990362 RHEA:33200 Catalysis of the reaction: butanal + NADH + H+ => n-butanol + NAD+. GO:1990363 obsolete response to hydrolysate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990363 response to hydrolysate OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of hydrolysate (any product of hydrolysis). GO:1990364 obsolete response to aldehyde biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990364 response to aldehyde OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldehyde. GO:1990360 PKM2 protein kinase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990360 PKM2-SAICAR complex|PKM2-SAICAR protein kinase complex A protein complex capable of phosphorylating a large number of protein targets. Contributes to cell proliferation under glycose starvation conditions. In human, the complex is present as a dimer. CHEBI:134398 D-proline betaine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134398 GO:0039698 polyadenylation of viral mRNA by polymerase stuttering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039698 VZ:1916 polyA stuttering Polyadenylation of viral mRNA through a polymerase stuttering mechanism. The stop signal present at the end of each gene comprises a stretch of uridine on which the viral polymerase acquires a stuttering behavior: after each adenine inserted, the polymerase moves back one nucleotide along with the mRNA. It resumes transcription adding a new adenine, then again moves back, thereby producing a polyA tail. CHEBI:134399 ADP-5-ethyl-4-methylthiazole-2-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134399 GO:0039699 viral mRNA cap methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039699 IFIT mRNA restriction evasion by virus Methylation of the 2'-O-ribose of the first or second transcribed nucleotide of a viral mRNA. Methylation allows evasion of the host innate immune response, which degrades cap0 (non-methylated) mRNAs. GO:0039692 single stranded viral RNA replication via double stranded DNA intermediate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039692 VZ:1937 retroviral genome replication|viral ssRNA replication via dsDNA intermediate A viral genome replication where the template is single-stranded RNA (ssRNA), and which proceeds via a double stranded DNA (dsDNA) intermediate molecule. Viral genomic RNA is first reverse transcribed into dsDNA, which integrates into the host chromosomal DNA, where it is transcribed by host RNA polymerase II. GO:0039693 viral DNA genome replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039693 viral DNA-dependent DNA replication|DNA-dependent viral DNA replication|viral DNA replication The replication of a viral DNA genome. GO:0039690 positive stranded viral RNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039690 VZ:1116 ss(+) viral RNA replication A viral genome replication process where the template genome is positive stranded, single stranded RNA ((+)ssRNA). Replication of the positive strand leads to dsRNA formation, which in turn is transcribed into positive single stranded RNA. CHEBI:134390 beta-D-Delta(4)-GlcpA-(1->4)-beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-D-Glcp(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134390 GO:0039691 double stranded viral RNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039691 VZ:1936 A viral genome replication process where the template genome is double stranded RNA (dsRNA). Genomic dsRNA is first transcribed into single-stranded (ss) mRNA, which is then replicated to ds-genomic RNA. CHEBI:134391 3,4,6-trichlorocatechol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134391 GO:0039696 RNA-templated viral transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039696 A transcription process that uses viral RNA as a template. CHEBI:134396 secondary allylic alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134396 GO:1990369 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990369 CHEBI:134397 tertiary allylic alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134397 GO:0039697 negative stranded viral RNA transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039697 VZ:1096 A viral transcription process that uses negative stranded (-) single stranded (ss) RNA as a template. CHEBI:134394 primary allylic alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134394 GO:0039694 viral RNA genome replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039694 The replication of a viral RNA genome. GO:0039695 DNA-templated viral transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039695 VZ:1942 A transcription process that uses a viral DNA as a template. GO:1990376 obsolete negative regulation of G1/S transition of mitotic cell cycle by positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990376 OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation that results in negative regulation of mitotic G1/S transition. GO:1990377 organomineral extracellular matrix biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990377 An extracellular matrix consisting of a densely packed organomineral assembly in which the mineral phase represents the majority of the material by weight. GO:1990378 upstream stimulatory factor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990378 IntAct:EBI-9518693 USF1-USF2 heterodimer|USF2 homodimer|USF1 homodimer|USF complex A protein complex capable of sequence-specific DNA binding RNA polymerase II transcription factor activity through binding to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3'). Found in a variety of viral and cellular promoters. GO:1990379 lipid transport across blood-brain barrier biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990379 lipid transport across blood brain barrier The directed movement of lipid molecules passing through the blood-brain barrier. GO:1990372 obsolete process resulting in tolerance to organic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990372 OBSOLETE. A response that results in a state of tolerance to organic acid. GO:0001077 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001077 GO:0001078 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001078 GO:1990373 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990373 GO:1990374 Kir2 inward rectifier potassium channel complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990374 IntAct:EBI-9510554|IntAct:EBI-9511072 Kir2.1 complex A inward rectifier potassium channel complex. Homo- or heterotetramer composed of subunits of the eukaryotic Kir2 protein family. Plays a key role in maintaining the correct resting potential in eukaryotic cells. GO:0001079 nitrogen catabolite regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001079 regulation of transcription from RNA polymerase II promoter by nitrogen catabolites A transcription regulation process in which the presence of one nitrogen source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other nitrogen sources. GO:1990375 baculum development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990375 os penis development|penis bone development|penile bone development The reproductive developmental process whose specific outcome is the progression of the baculum over time, from its formation to the mature structure. GO:0001073 transcription antitermination factor activity, DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001073 DNA binding transcription antitermination factor activity Binds to DNA, typically within region of the promoter and transcribed region, to promote readthrough of a transcription termination site and thus extending the length of the RNA transcript produced. Examples of antitermination factors which bind DNA include the lambda Q protein. GO:0001074 obsolete transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding involved in preinitiation complex assembly biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001074 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding involved in preinitiation complex assembly|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly OBSOLETE. Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to promote assembly of the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription from an RNA polymerase II promoter. GO:0001075 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001075 GO:1990370 obsolete process resulting in tolerance to aldehyde biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990370 OBSOLETE. A response that results in a state of tolerance to aldehyde. GO:0001076 obsolete transcription factor activity, RNA polymerase II transcription factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001076 RNA polymerase II transcription factor binding transcription factor activity OBSOLETE. Interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. GO:1990371 obsolete process resulting in tolerance to phenol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990371 OBSOLETE. A response that results in a state of tolerance to phenol. GO:0001070 RNA-binding transcription regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001070 RNA binding transcription factor activity|RNA binding transcription regulator activity A transcription regulator activity that modulates the transcription of specific gene sets via selective and non-covalent binding to a specific RNA sequence. This function is known to occur in phages and viruses, for example the lambda N and the HIV tat proteins are necessary to allow RNA polymerase to read through terminator sequences. GO:0001071 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001071 GO:0001072 transcription antitermination factor activity, RNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001072 RNA binding transcription antitermination factor activity Binds to RNA, typically within the nascent RNA transcript, to promote readthrough of a transcription termination site and thus extending the length of the RNA transcript produced. Examples of antitermination factors which bind the nascent RNA include the lambda N protein and the HIV-1 tat protein. CHEBI:134367 2-bromocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134367 GO:0039689 negative stranded viral RNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039689 VZ:1096 (-)ss viral RNA replication A viral genome replication process where the template genome is negative stranded, single stranded RNA ((-)ssRNA). CHEBI:134368 5a,11a-dehydrooxytetracycline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134368 GO:0039687 viral DNA strand displacement replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039687 VZ:1940 A viral DNA replication process where only one strand is replicated at once, and which releases a single stranded DNA (ssDNA). GO:0039688 viral double stranded DNA replication via reverse transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039688 VZ:1938 dsDNA replication via RNA intermediate|viral RNA-dependent DNA replication|RNA-dependent viral DNA replication A DNA replication process that uses viral RNA as a template for RNA-dependent DNA polymerases (e.g. reverse transcriptase) that synthesize the new strands. CHEBI:134366 12alpha-hydroxy-3-oxochola-4,6-dien-24-oyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134366 GO:0039681 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0039681 GO:0039682 rolling circle viral DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039682 A process of unidirectional viral DNA replication that takes place on a circular DNA to rapidly produce numerous copies of the viral genome. Involves creating a nick in one strand of the circular DNA molecule at the origin of replication. DNA is then synthesized by DNA polymerase. Using the non-nicked strand as a template, replication proceeds around the circular DNA molecule, displacing the nicked strand as single-stranded DNA. GO:0039680 actin-dependent intracellular transport of virus towards nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039680 VZ:991 actin-dependent intracellular transport of viral material towards nucleus|actin-dependent inwards viral transport The directed movement of a virus, or part of a virus, towards the host cell nucleus using actin filaments. GO:0039685 rolling hairpin viral DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039685 VZ:2656 ssDNA rolling hairpin viral DNA replication A viral DNA replication process where a 3' hairpin structure in the viral single-stranded DNA (ssDNA) template serves as a primer for host enzymes to synthesize DNA. CHEBI:134363 tertiary amine oxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134363 GO:0039686 bidirectional double-stranded viral DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039686 VZ:1939 viral bidirectional dsDNA replication A viral DNA replication process where replication occurs in both directions from the starting point. This creates two replication forks, moving in opposite directions. CHEBI:134364 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134364 GO:0039683 rolling circle double-stranded viral DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039683 VZ:2676 dsDNA rolling circle replication A rolling circle viral DNA replication that begins with a double-stranded viral DNA genome. CHEBI:134361 allylic alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134361 CHEBI:134362 homoallylic alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134362 GO:0039684 rolling circle single-stranded viral DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039684 VZ:1941 ssDNA rolling circle replication A rolling circle viral DNA replication that begins with a single-stranded viral DNA genome. GO:1990387 isogloboside biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990387 CHEBI:78257 The chemical reactions and pathways resulting in the formation of a lactosyl-ceramide derivative in which a galactose is linked to the galactose via an alpha 1,3 linkage (vs alpha 1,4 for globosides). GO:1990388 xylem-to-phloem iron transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990388 The directed movement of iron ions into the phloem from the xylem. GO:1990389 CUE1-UBC7 ubiquitin-conjugating enzyme complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990389 IntAct:EBI-9207004 CUE1-UBC7 ubiquitin-conjugating enzyme (E2) A protein complex capable of ubiquitin-conjugating enzyme activity during ER-associated protein degradation (ERAD). In S. cerevisiae, UBC7 is the ubiquitin-conjugating enzyme (E2) and requires binding to the ER surface by CUE1. GO:1990383 cellular response to biotin starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990383 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of biotin. GO:0001088 obsolete transcription factor activity, TFIIE-class binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001088 TFIIE-class binding transcription factor activity OBSOLETE. Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor of the TFIIE class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well. GO:1990384 hyaloid vascular plexus regression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990384 The developmental process in which the hyaloid vascular plexus is destroyed as a part of its normal progression. GO:0001089 obsolete transcription factor activity, TFIIF-class transcription factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001089 TFIIF-class binding transcription factor activity OBSOLETE. Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor of the TFIIF class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well. GO:1990385 meiotic spindle midzone biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990385 The area in the center of the meiotic spindle where the spindle microtubules from opposite poles overlap. GO:1990386 mitotic cleavage furrow ingression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990386 Advancement of the mitotic cleavage furrow from the outside of the cell inward towards the center of the cell. The cleavage furrow acts as a 'purse string' which draws tight to separate daughter cells during mitotic cytokinesis and partition the cytoplasm between the two daughter cells. The furrow ingresses until a cytoplasmic bridge is formed. GO:0001084 obsolete transcription factor activity, TFIID-class binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001084 TFIID-class binding transcription factor activity OBSOLETE. Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor of the TFIID class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well. GO:1990380 Lys48-specific deubiquitinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990380 Reactome:R-HSA-5690870 K48-specific deubiquitinating activity|K48-specific deubiquitinase activity Hydrolysis of Lys48-linked ubiquitin unit(s) from a ubiquitinated protein. GO:0001085 RNA polymerase II transcription factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001085 Interacting selectively and non-covalently with an RNA polymerase II transcription factor, any protein required to initiate or regulate transcription by RNA polymerase II. GO:0001086 obsolete transcription factor activity, TFIIA-class binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001086 TFIIA-class binding transcription factor activity OBSOLETE. Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor of the TFIIA class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well. GO:1990381 ubiquitin-specific protease binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990381 deubiquitinating enzyme binding|deubiquitinase binding Interacting selectively and non-covalently with a ubiquitin-specific protease. GO:0001087 obsolete transcription factor activity, TFIIB-class binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001087 TFIIB-class binding transcription factor activity OBSOLETE. Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor of the TFIIB class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well. GO:1990382 obsolete melanosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990382 melanosome biogenesis OBSOLETE. The aggregation, arrangement and bonding together of a set of components to form a melanosome, a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. GO:0001080 nitrogen catabolite activation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001080 positive regulation of transcription from RNA polymerase II promoter by nitrogen catabolites A transcription regulation process in which the presence of one nitrogen source leads to an increase in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other nitrogen sources. GO:0001081 nitrogen catabolite repression of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001081 negative regulation of transcription from RNA polymerase II promoter by nitrogen catabolites A transcription regulation process in which the presence of one nitrogen source leads to a decrease in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other nitrogen sources. GO:0001082 obsolete transcription factor activity, RNA polymerase I transcription factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001082 RNA polymerase I transcription factor binding transcription factor activity OBSOLETE. Interacting selectively and non-covalently with an RNA polymerase I transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. GO:0001083 obsolete transcription factor activity, RNA polymerase II basal transcription factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001083 RNA polymerase II basal transcription factor binding transcription factor activity OBSOLETE. Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. GO:0039678 viral genome ejection through host cell envelope biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039678 phage genome ejection|viral genome injection through bacterial membranes Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm. Caudovirales carry an ejection apparatus that can be long and contractile, long and noncontractile, or short, and is able to penetrate the host cell envelope to deliver the viral genome into the host cell cytoplasm. GO:0039679 viral occlusion body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0039679 VZ:1949 A crystalline protein matrix surrounding the nucleocapsids of some insect viruses after their release in the environment. Produced in the host cell, the occlusion body protects the infectious virion after death of the host. GO:0039676 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0039676 GO:0001090 obsolete transcription factor activity, TFIIH-class binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001090 TFIIH-class binding transcription factor activity OBSOLETE. Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor of the TFIIH class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well. GO:0039677 exit of virus from host cell nucleus via nuclear envelope disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039677 VZ:2176 exit of virus from host cell nucleus via nuclear envelope breakdown The directed movement of the viral genome or a viral particle out of the host cell nucleus that involves disruption of the nuclear membrane envelope by the virus. GO:0039670 viral capsid, turret biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0039670 A turret-like appendage formed at the vertices of an icosahedral capsid. GO:0039671 evasion by virus of host natural killer cell activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039671 protection by virus against host NK cell cytotoxicity|modulation of host NK-cell activity by virus|evasion by virus of host natural killer cell response|evasion by virus of host NK cell killing|suppression by virus of host natural killer cell function|viral immunoevasion of host NK cell Any process by which a virus avoids the effects mediated by the host organism's natural killer (NK) cells. CHEBI:134371 2-acyl-4-prenylphloroglucinol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134371 GO:0039674 exit of virus from host cell nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039674 VZ:2177 The directed movement of the viral genome or a viral particle out of the host cell nucleus. GO:0039675 exit of virus from host cell nucleus through nuclear pore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039675 VZ:1953 nuclear pore exit of virus|exit of virus from host cell nucleus through nuclear pore complex|viral enome export through nuclear pore The directed movement of the viral genome or a viral particle out of the host cell nucleus through the nuclear pore. GO:0039672 suppression by virus of host natural killer cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039672 suppression by virus of host NK-cell activation Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation in the host. GO:0039673 evasion by virus of host dendritic cell activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039673 evasion by virus of host dendritic cell response|impairing dendritic cell function by virus|modulation of host dendritic cell activity by virus Any process by which a virus avoids the effects mediated by the host organism's dendritic cells. GO:0001059 transcription by RNA polymerase IV biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001059 transcription from RNA pol IV promoter|transcription from RNA polymerase IV promoter The synthesis of RNA from a DNA template by RNA polymerase IV, originating at a Pol IV-specific promoter. GO:1990310 type-III dockerin domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990310 Interacting selectively and non-covalently with a type-III dockerin domain of a protein. Type-III dockerin domain is the binding partner of type-III cohesin domain. CHEBI:506227 N-acetyl-D-glucosamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_506227 GO:1990311 type-I cohesin domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990311 Interacting selectively and non-covalently with a type-I cohesin domain of a protein. Type-I cohesin domain is the binding partner of type-I dockerin domain. GO:1990312 type-II cohesin domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990312 Interacting selectively and non-covalently with a type-II cohesin domain of a protein. Type-II cohesin domain is the binding partner of type-II dockerin domain. GO:1990313 type-III cohesin domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990313 Interacting selectively and non-covalently with a type-III cohesin domain of a protein. Type-III cohesin domain is the binding partner of type-III dockerin domain. GO:0001055 RNA polymerase II activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001055 Reactome:R-HSA-6814559|Reactome:R-HSA-6814549 DNA-directed RNA polymerase activity involved in transcription from RNA polymerase II promoter Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase II specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'. GO:0001056 RNA polymerase III activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001056 Reactome:R-HSA-1964482 DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase III specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'. GO:0001057 RNA polymerase IV activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001057 DNA-directed RNA polymerase activity involved in transcription from RNA polymerase IV promoter Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase IV specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'. GO:0001058 RNA polymerase V activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001058 DNA-directed RNA polymerase activity involved in transcription from RNA polymerase V promoter Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase V specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'. GO:0001051 plastid single-subunit type RNA polymerase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001051 Interacting selectively and non-covalently with a single subunit plastid RNA polymerase enzyme, which is composed of a single catalytic subunit similar to the RNA polymerase enzymes from phages T3, T7, and SP6. GO:0001052 plastid PEP RNA polymerase core enzyme binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001052 Interacting selectively and non-covalently with the bacterial-type plastid PEP RNA polymerase core enzyme, typically consisting of two alpha, one beta, one beta prime, and one double prime subunit. GO:0001053 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001053 GO:0001054 RNA polymerase I activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001054 DNA-directed RNA polymerase activity involved in transcription from RNA polymerase I promoter Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase I specific promoter to direct initiation and catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'. GO:0001050 single-subunit type RNA polymerase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001050 T7-type RNA polymerase binding|T3/T7 type RNA polymerase binding|T3-type RNA polymerase binding|SP6-type RNA polymerase binding Interacting selectively and non-covalently with a single subunit RNA polymerase enzyme, which is composed of a single catalytic subunit similar to the RNA polymerase enzymes from phages T3, T7, and SP6. GO:0039667 viral entry into host cell via pilus retraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039667 The uptake of a virus or viral genetic material into a host cell which occurs through retraction of a virion-bound pilus. CHEBI:134345 deoxyhumulone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134345 GO:0039668 viral entry into host cell via pilus basal pore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039668 filamentous viral entry into host cell via pilus retraction The uptake of a virus or viral genetic material into a host cell which occurs through retraction of the virion-bound pilus, followed by entry of the viral genome into the host cell through the pilus basal pore. Filamentous bacteriophages absorb to the tip of the F-pili and can enter the bacterial cell in this way. PR:000004972 calcitonin receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000004972 CALCR|CT-R A calcitonin receptor protein that is a translation product of the human CALCR gene or a 1:1 ortholog thereof. CHEBI:134346 2-acyl-4,6-diprenylphloroglucinol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134346 GO:0039665 permeabilization of host organelle membrane involved in viral entry into host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039665 VZ:985 viral penetration via permeabilization of host organellar membrane|viral penetration via perforation of host organellar membrane by virus|viral penetration via host endosomal membrane disruption by virus|viral entry into host cell via permeabilization of host organelle membrane|viral membrane-penetration protein Induction of organellar membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with a viral capsid. Results in release of the virus contents from an organelle into the host cell cytoplasm. CHEBI:134343 lupulone(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134343 GO:0039666 virion attachment to host cell pilus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039666 VZ:981 pilus-adsorption protein|viral attachment to host cell pilus|pilus-mediated viral adsorption onto host cell|pilus-mediated viral attachment to host cell The process by which a virion attaches to a host cell by binding to a pilus on the host cell surface. Pili are retractile filaments that protrude from gram-negative bacteria. Filamentous viruses can attach to the pilus tip, whereas icosahedral viruses can attach to the pilus side. CHEBI:134344 ergothioneine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134344 CHEBI:134349 colupulone(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134349 GO:0015696 ammonium transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015696 ammonia transport The directed movement of ammonium into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ammonium is the cation NH4+ which is formed from N2 by root-nodule bacteria in leguminous plants and is an excretory product in ammonotelic animals. GO:0015697 quaternary ammonium group transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015697 quaternary amine transport|quaternary ammonium compound transport The directed movement into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore of quaternary ammonium compounds, any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups. CHEBI:134347 glandicoline B biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134347 GO:0039669 viral entry into host cell via pilus retraction and membrane fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039669 The uptake of a virus into a host cell which occurs via retraction of the viral-bound pilus to bring the virus in contact with the host cell membrane, followed by fusion of the bacteriophage membrane with the host outer membrane. GO:0015698 inorganic anion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015698 The directed movement of inorganic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage. CHEBI:134348 beta-bitter acid(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134348 GO:0015699 antimonite transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015699 The directed movement of antimonite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:1990318 collagen type XIX trimer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990318 IntAct:EBI-2529092 A collagen homotrimer of alpha1(XIX) chains; type XIX collagen triple helices localize to basement membrane zones in differentiating muscle cells. GO:0015692 lead ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015692 The directed movement of lead (Pb) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0039660 structural constituent of virion biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0039660 viral matrix protein The action of a molecule that contributes to the structural integrity of a virion. GO:1990319 collagen type XX trimer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990319 IntAct:EBI-2529132 A collagen homotrimer of alpha1(XX) chains. GO:0015693 magnesium ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015693 magnesium transport The directed movement of magnesium (Mg) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015694 mercury ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015694 mercury transport|mercuric ion transport The directed movement of mercury (Hg) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. PR:000004978 calmodulin biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000004978 CALML2|CALM|CAMIII|CAMC|CaM|CAM3 A protein that is a translation product of the human CALM1, CALM2, or CALM3 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. GO:0015695 organic cation transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015695 The directed movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic cations are atoms or small molecules with a positive charge which contain carbon in covalent linkage. GO:1990314 cellular response to insulin-like growth factor stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990314 cellular response to insulin-like growth factor Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin-like growth factor stimulus. GO:0039663 membrane fusion involved in viral entry into host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039663 fusion of virus membrane with host membrane during viral entry|fusion of virus membrane with host membrane|viral entry into host cell via membrane fusion Merging of the virion membrane and a host membrane (host plasma membrane or host organelle membrane) that is involved in the uptake of a virus into a host cell. CHEBI:134341 2-(3-methylbutanoyl)-4-prenylphloroglucinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134341 GO:0039664 lysis of host organelle involved in viral entry into host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039664 VZ:984 viral entry into host cell via lysis of host organelle membrane|viral penetration via lysis of host organellar membrane|viral entry into host cell via endosome membrane lysis|viral membrane-lytic protein The viral-induced lysis of an organelle (endosome, lysosome, or caveosome) that is involved in the uptake of a virus into a host cell. Occurs once the virus is within the organelle, and results in transfer of the viral contents from the organelle compartment into the cytoplasm. GO:1990315 Mcs4 RR-MAPKKK complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990315 A protein complex that consists of a phospho relay component and a MAPK cascade component. The complex is involved in signaling oxidative stress and osmostress. CHEBI:134342 2-isobutyryl-4-prenylphloroglucinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134342 GO:0039661 host organelle outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0039661 The outer, i.e. cytoplasm-facing in a cellular organelle, lipid bilayer of an organelle envelope, occurring in a host cell. GO:0015690 aluminum cation transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015690 aluminium transport|aluminum ion transport|aluminium ion transport|aluminum transport The directed movement of aluminum (Al) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:1990316 Atg1/ULK1 kinase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990316 IntAct:EBI-2352849 autophagy-initiation complex|ULK1-ATG13-RB1CC1 complex|ULK1 signaling complex|ULK1 complex|ULK1-ATG13-FIP200 complex|Atg1p signalling complex|ATG1/ULK1 signaling complex|ULK complex|ATG1-ATG13 complex|ATG1 kinase complex A protein complex consisting of Atg1 (or Atg1 homologs e.g. ULK1, ULK2 in mammals) and Atg13 along with other proteins that regulate its function (e.g. Atg17 in yeast or RB1CC1(FIP200) in mammals). This complex has serine/threonine protein kinase activity and is involved in autophagosome formation. GO:1990317 Gin4 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990317 IntAct:EBI-2431392 Gin4-septin complex A protein complex involved in septin ring formation during mitosis. In Saccharomyces cerevisiae it consists of BNI5, CDC3, CDC10, CDC11, CDC12, GIN4, NAP1 and SHS1. At least 2 GIN4 molecules are involved. GO:0039662 host cell outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0039662 outer membrane of host cell|host cell envelope outer membrane A lipid bilayer that forms the outermost layer of the cell envelope, occurring in a host cell. GO:0015691 cadmium ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015691 cadmium transport The directed movement of cadmium (Cd) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:134340 2-(2-methylbutanoyl)-4-prenylphloroglucinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134340 GO:1990321 collagen type XXII trimer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990321 IntAct:EBI-2529189 A collagen homotrimer of alpha1(XXII) chains; type XXII collagen triple helices acts as a cell adhesion ligand for skin epithelial cells and fibroblasts. GO:1990322 collagen type XXIII trimer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990322 IntAct:EBI-2529234 A collagen homotrimer of alpha1(XXIII) chains; type XXIII collagen triple helices span the plasma membrane. GO:1990323 collagen type XXIV trimer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990323 IntAct:EBI-2529258 A collagen homotrimer of alpha1(XXIV) chains; type XXIV collagen triple helices may participate in regulating type I collagen fibrillogenesis at specific anatomical locations during fetal development. GO:1990324 collagen type XXVI trimer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990324 IntAct:EBI-2529362 A collagen homotrimer of alpha1(XXVI) chains. PO:0004511 seed trichome biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0004511 pubescence (related)|seed hair (exact)|種子毛（毛茸、糸状体、毛状突起体） (Japanese, exact)|tricoma de la semilla (Spanish, exact) A trichome that develops from seed coat epidermis. GO:0001066 plastid single subunit type RNA polymerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001066 Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a single subunit type plastid RNA polymerase specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'. GO:0001067 regulatory region nucleic acid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001067 Interacting selectively and non-covalently with a nucleic acid region that regulates a nucleic acid-based process. Such processes include transcription, DNA replication, and DNA repair. GO:0001068 transcription regulatory region RNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001068 Interacting selectively and non-covalently with a RNA region within the transcript that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. GO:1990320 collagen type XXI trimer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990320 IntAct:EBI-2529143 A collagen homotrimer of alpha1(XXI) chains; type XXI collagen triple helices found in the extracellular matrix component of blood vessel walls and in the cytoplasm of cultured human aortic smooth muscle. GO:0001069 regulatory region RNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001069 Interacting selectively and non-covalently with a RNA region that regulates a nucleic acid-based process. Such processes include transcription, DNA replication, and DNA repair. GO:0001062 plastid PEP-A RNA polymerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001062 Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a plastid PEP-A RNA polymerase II specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'. GO:0001063 plastid PEP-B RNA polymerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001063 Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a plastid PEP-B RNA polymerase II specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'. GO:0001064 single subunit type RNA polymerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001064 T3/T7 type RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a single-subunit-type RNA polymerase-specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'. GO:0001065 mitochondrial single subunit type RNA polymerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001065 Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a single-subunit-type mitochondrial RNA polymerase-specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'. GO:0001060 transcription by RNA polymerase V biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001060 transcription from RNA polymerase V promoter|transcription from RNA pol V promoter The synthesis of RNA from a DNA template by RNA polymerase V, originating at a Pol V-specific promoter. GO:0001061 bacterial-type RNA polymerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001061 Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a bacterial-type specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'. CHEBI:134356 8-methylmenaquinone-6 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134356 GO:0039656 modulation by virus of host gene expression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039656 regulation by virus of host gene expression The process in which a virus effects a change in gene expression in its host organism. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. GO:0039657 suppression by virus of host gene expression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039657 VZ:1582 host gene expression shutoff by virus Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of gene expression in the host organism. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. CHEBI:134357 8-methylmenaquinol-6 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134357 GO:0039654 fusion of virus membrane with host endosome membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039654 VZ:992 viral penetration via endocytosis followed by caveolae-mediated membrane fusion with the endosome membrane|viral penetration via endocytosis followed by clathrin-mediated membrane fusion with the endosome membrane|viral entry into host cell via endocytosis followed by membrane fusion with host endosome|viral entry into host cell via endocytosis followed by membrane fusion with the endosome membrane|viral entry into host cell via caveolin-mediated endocytosis followed by membrane fusion with the endosome membrane|viral entry into host cell via clathrin-mediated endocytosis followed by membrane fusion with the endosome membrane|viral entry into host cell via caveolae-mediated endocytosis followed by membrane fusion with the endosome membrane|fusion of virus membrane with host endosomal membrane Fusion of a virus membrane with a host endosome membrane. Occurs after internalization of the virus through the endosomal pathway, and results in release of the virus contents into the cell. CHEBI:134354 deoxyadlupulone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134354 GO:0039655 obsolete transport of virus in host, cell to cell via plasmodesmata biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039655 VZ:1018 viral movement protein|spread of virus in host, cell to cell via plasmodesmata OBSOLETE. The transport of a virus between adjacent cells in a multicellular organism using plasmodesmata. Plasmodesma is a fine cytoplasmic channel found in all higher plants, which connects the cytoplasm of one cell to that of an adjacent cell. GO:0039658 TBK1-IKKE-DDX3 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0039658 TBK1-IKBKE-DDX3 complex A protein complex containing TBK1 (TANK-binding kinase 1), IKBKE (I-Kappa-B kinase epsilon/IKKE/IKK-epsilon) and the DEAD box family RNA helicase DDX3. CHEBI:134358 8-geranylumbelliferone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134358 CHEBI:134359 8-geranylesculetin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134359 GO:0039659 obsolete suppression by virus of host TBK1-IKBKE-DDX3 complex activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039659 VZ:719 suppression by virus of host TBK1-IKKE-DDX3 complex activity|inhibition of host TBK1-IKBKE-DDX3 complex by virus OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of the host TBK1-IKBKE-DDX3 complex. GO:1990329 IscS-TusA complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990329 IntAct:EBI-8869931 A heterotetrameric protein complex involved in the sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm5s2U) at tRNA wobble positions. In E. coli it consists of a central IscS dimer with the two TusA protomers bound to one of the IscS units each via persulfide (-SSH) groups. GO:1990325 collagen type XXVII trimer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990325 IntAct:EBI-2529377 A collagen homotrimer of alpha1(XXVII) chains. These trimers form thin, non-striated fibrils. Type XXVII collagen triple helices play a role during the calcification of cartilage and the transition of cartilage to bone. GO:0039652 activation by virus of host NF-kappaB transcription factor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039652 VZ:841 activation of host NF-kappa-B by virus Any process in which a virus starts, promotes, or enhances the activity of the host transcription factor NF-kappaB. CHEBI:134352 adlupulone(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134352 GO:0039653 suppression by virus of host transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039653 VZ:1577 suppression by virus of host DNA-dependent transcription|host transcription shutoff by virus Any process in which a virus stops, prevents, or reduces the activity of host DNA-dependent transcription; the cellular synthesis of RNA on a template of DNA. Viral proteins can interfere with either host RNA polymerase or with transcription factors. GO:1990326 collagen type XXVIII trimer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990326 IntAct:EBI-2529426 A collagen homotrimer of alpha1(XXVIII) chains. CHEBI:134353 deoxycohumulone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134353 GO:0039650 suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039650 inhibition of host caspases by virus Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host caspase activity. Caspases are cysteine-type endopeptidases which contribute to the apoptotic process. GO:1990327 collagen type XXV trimer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990327 IntAct:EBI-2529312 A collagen homotrimer of alpha1(XXV) chains; type XXV collagen triple helices span the plasma membrane. CHEBI:134350 lipid A 4'-(2-aminoethyl diphosphate) oxoanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134350 GO:0039651 induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039651 induction by virus of host caspase activity|activation of host caspases by virus Any process in which a virus increases the frequency, rate or extent of host cysteine-type endopeptidase activity (also called caspase activity) which contributes to the apoptotic process. GO:1990328 RPB4-RPB7 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990328 IntAct:EBI-2945755 RNA polymerase II, RPB4-RPB7 subcomplex A protein complex that cycles between the nucleus where it is part of the RNA polymerase II and the cytoplasmic mRNA processing body where it mediates the two major cytoplasmic mRNA decay pathways. CHEBI:134351 lipid A 1-(2-aminoethyl diphosphate) oxoanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134351 GO:1990332 Ire1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990332 IntAct:EBI-8872439 ERN1 complex|IRE1 dimer A type-I transmembrane protein complex located in the endoplasmic reticulum (ER) consisting of an IRE1-IRE1 dimer, which forms in response to the accumulation of unfolded protein in the ER. The dimeric complex has endoribonuclease (RNase) activity and evokes the unfolded protein response (UPR) by cleaving an intron of a mRNA coding for the transcription factor HAC1 in yeast or XBP1 in mammals; the complex cleaves a single phosphodiester bond in each of two RNA hairpins (with non-specific base paired stems and loops of consensus sequence CNCNNGN, where N is any base) to remove an intervening intron from the target transcript. GO:0001037 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001037 GO:1990333 mitotic checkpoint complex, CDC20-MAD2 subcomplex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990333 IntAct:EBI-1270646 CDC20-MAD2 complex A protein complex involved in the spindle checkpoint, preventing the activation of the anaphase-promoting complex until all chromosomes are correctly attached in a bipolar fashion to the mitotic spindle. In budding yeast this complex consists of Mad2p and Cdc20p, and in mammalian cells it consists of MAD2 and CDC20. GO:0001038 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001038 GO:0001039 RNA polymerase III hybrid type promoter sequence-specific DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001039 RNA polymerase III hybrid type promoter DNA binding Interacting selectively and non-covalently with a sequence of DNA that is a part of a hybrid type promoter that controls transcription by RNA polymerase III (Pol III). A hybrid Pol III promoter contains both regulatory elements both upstream and downstream of the transcription initiation site. An example gene with such a promoter is the S. cerevisiae U6 gene. GO:1990334 Bfa1-Bub2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990334 IntAct:EBI-1271344 A protein complex that acts as a two-component GTPase-activating protein for Tem1 GTPase, thus regulating a signal transduction cascade, called the mitotic exit network (MEN), which is required for mitotic exit and cytokinesis. Bub2/Bfa1 keeps Tem1 inactive until the spindle is properly oriented, thus inhibiting MEN activation. CHEBI:76106 rac-laudanosoline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76106 GO:1990335 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990335 GO:0001033 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001033 GO:0001034 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001034 GO:0001035 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001035 GO:1990330 IscS-IscU complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990330 IntAct:EBI-8870238 A heterotetrameric protein complex involved in the sulfur transfer during iron-sulfur cluster assembly and in the modification of tRNA wobble positions. In E. coli it consisting of a central IscS dimer with the IscU protomers attached to one of the IscS units each via a disulfide (-SSH) group. GO:1990331 Hpa2 acetyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990331 IntAct:EBI-8871758 A tetrameric protein complex capable of acetyltransferase activity. It can catalyze the transfer of an acetyl group from acetyl-CoA to an acceptor residue on histone H-3, histone H-4, or on polyamines. The complex is also capable of acetylating certain small basic proteins. The two Hpa2 dimers that make up the tetramer are held together by interactions between the bound acetyl-CoA molecules. GO:0001036 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001036 GO:0001030 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001030 GO:0001031 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001031 GO:0001032 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001032 GO:0039645 modulation by virus of host G1/S transition checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039645 VZ:880 G1/S host cell cycle checkpoint dysregulation by virus Any viral process that modulates the frequency, rate or extent of the host cell G1/S transition checkpoint. GO:0015678 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015678 GO:0039646 modulation by virus of host G0/G1 transition checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039646 VZ:881 G0/G1 host cell cycle checkpoint dysregulation by virus Any viral process that modulates the frequency, rate or extent of the host cell G0/G1 transition checkpoint. GO:0015679 plasma membrane copper ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015679 plasma membrane copper transport The directed movement of copper ions across the plasma membrane. GO:0039643 host cell viral nucleoid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0039643 The region of a host cell that contains the viral genome. GO:0039644 suppression by virus of host NF-kappaB transcription factor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039644 VZ:695 inhibition of host NF-kappa-B by virus Any process in which a virus stops, prevents, or reduces the activity of host NF-kappaB activity. GO:0015674 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015674 GO:0039649 modulation by virus of host ubiquitin-protein ligase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039649 modulation of host E3 ubiquitin ligases by virus The process in which a virus effects a change in host ubiquitin-protein ligase activity. Ubiquitin-protein ligase activity catalyzes the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine. GO:0015675 nickel cation transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015675 The directed movement of nickel (Ni) cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0039647 suppression by virus of host poly(A)-binding protein activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039647 suppression by virus of host PABP activity|inhibition of host poly(A)-binding protein by virus Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host poly(A)-binding protein (PABP) activity. PABP binds to the poly(A) tail of mRNA to facilitate translation. GO:0015676 vanadium ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015676 The directed movement of vanadium (V) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:134326 2-(2-methylbutanoyl)phloroglucinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134326 GO:0039648 modulation by virus of host protein ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039648 modulation of host ubiquitin pathway by virus Any process in which a virus modulates the frequency, rate or extent of protein ubiquitination in the host organism. Ubiquitination is the process in which one or more ubiquitin groups are added to a protein. GO:0015677 copper ion import biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015677 copper ion uptake The directed movement of copper ions into a cell or organelle. GO:0015670 carbon dioxide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015670 The directed movement of carbon dioxide (CO2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015671 oxygen transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015671 The directed movement of oxygen (O2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:76101 (S)-laudanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76101 GO:0015672 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015672 GO:0015673 silver ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015673 silver transport The directed movement of silver (Ag) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:76104 kaempferol 3-O-beta-D-galactoside(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76104 GO:0039641 viral inner membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0039641 virion inner membrane The lipid bilayer of a virion contained inside the protein capsid. GO:1990336 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990336 GO:0039642 virion nucleoid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0039642 The region of a virion in which the nucleic acid is confined. GO:1990337 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990337 CHEBI:76105 (R)-laudanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76105 CHEBI:76102 laudanine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76102 GO:1990338 laminin-14 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990338 IntAct:EBI-2530020 laminin-423 A laminin complex composed of alpha4, beta2 and gamma3 polypeptide chains. GO:0039640 viral release by cytolysis via suppression of host peptidoglycan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039640 cytolysis by virus via suppression of host peptidoglycan biosynthetic process|viral exit by cytolysis via suppression of host peptidoglycan biosynthetic process The killing by a virus of host cell by cytolysis, caused by a virus stopping, preventing, or reducing peptidoglycan biosynthesis in the host organism. Peptidoglycans are any of a class of glycoconjugates found in bacterial cell walls. GO:1990339 laminin-522 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990339 IntAct:EBI-2530034 laminin-522 A laminin complex composed of alpha5, beta2 and gamma2 polypeptide chains. CHEBI:76103 laudanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76103 GO:0001048 RNA polymerase IV core binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001048 Interacting selectively and non-covalently with RNA polymerase IV core enzyme, a multisubunit eukaryotic nuclear RNA polymerase found in plants and involved in siRNA production. GO:1990343 heterochromatin domain biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990343 HOOD A region of heterochromatin that is formed dynamically under specific growth conditions by a process that requires RNAi, and is enriched in histone H3 methylated on lysine 9 (H3K9me). GO:1990344 secondary cell septum biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990344 A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a secondary cell septum following nuclear division. GO:0001049 RNA polymerase V core binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001049 Interacting selectively and non-covalently with RNA polymerase V core enzyme, a multisubunit eukaryotic nuclear RNA polymerase found in plants and involved in production of noncoding transcripts at target loci for silencing. GO:1990345 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990345 GO:1990346 BID-BCL-xl complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990346 IntAct:EBI-822526|IntAct:EBI-709568|IntAct:EBI-822507 A heterodimeric protein complex consisting of BID and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators. GO:0001044 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001044 GO:1990340 laminin-15 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990340 IntAct:EBI-2530049 laminin-523 A laminin complex composed of alpha5, beta2 and gamma3 polypeptide chains. GO:0001045 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001045 GO:0001046 core promoter sequence-specific DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001046 core promoter binding Interacting selectively and non-covalently with a sequence of DNA that is part of a core promoter region. The core promoter is composed of the transcription start site and binding sites for the RNA polymerase and the basal transcription machinery. The transcribed region might be described as a gene, cistron, or operon. GO:1990341 thrombospondin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990341 IntAct:EBI-2530370|IntAct:EBI-9251408|IntAct:EBI-9251502|IntAct:EBI-9251524|IntAct:EBI-9251379|IntAct:EBI-9251455|IntAct:EBI-2530917|IntAct:EBI-2530975|IntAct:EBI-2530961|IntAct:EBI-2531058 A homotrimeric or homopentameric glycoprotein that functions at the interface of the cell membrane and the extracellular matrix through its interactions with proteins and proteoglycans, such as collagens, integrins and fibronectin, to regulate matrix structure and cellular behaviour. GO:0001047 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001047 GO:1990342 heterochromatin island biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990342 A region of facultative heterochromatin formed dynamically at specific loci in response to environmental signals, independently of RNAi. GO:0001040 obsolete RNA polymerase III hybrid type promoter TFIIIB-type transcription factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001040 OBSOLETE. Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III hybrid type promoter, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex. GO:0001041 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001041 GO:0001042 RNA polymerase I core binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001042 Interacting selectively and non-covalently with RNA polymerase I core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of seventeen subunits. GO:0001043 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001043 GO:0039634 killing by virus of host cell during superinfection exclusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039634 killing by virus of host cells involved in superinfection exclusion|Rex exclusion|killing by virus of host cells during superinfection exclusion The viral-killing of a host cell by a pre-existing virus in response to a subsequent infection of the host cell by second virus. GO:0015689 molybdate ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015689 The directed movement of molybdate (MoO4 2-) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Molybdate is the bivalent anion derived from molybdic acid. GO:0039635 suppression by virus of host peptidoglycan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039635 viral inhibition of host peptidoglycan biosynthesis Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of peptidoglycan biosynthesis in the host organism. Peptidoglycans are any of a class of glycoconjugates found in bacterial cell walls. GO:0039632 RNA translocase activity involved in viral RNA genome packaging biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0039632 viral RNA packaging activity|RNA packaging ATPase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive movement along a single- or double-stranded RNA molecule, which contributes to the packaging of viral RNA into a nucleocapsid. GO:0039633 killing by virus of host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039633 killing by phage of host cells|killing by virus of host cells Any process mediated by a virus that results in the death of a cell in the host organism. GO:0015685 ferric-enterobactin import into cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015685 ferric-enterobactin transport A process in which ferric-enterobactin, the iron-bound form of the siderophore enterobactin, is transported into the cell by specific cell surface receptors. GO:0039638 lipopolysaccharide-mediated virion attachment to host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039638 virion attachment, binding to host lipopolysaccharide|LPS binding involved in viral attachment to host cell|lipopolysaccharide binding involved in viral attachment to host cell The process by which a virion attaches to a host cell by binding to a lipopolysaccharide (LPS) on the host cell surface. GO:0015686 ferric triacetylfusarinine C import into cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015686 ferric triacetylfusarinine C transport The directed movement of ferric triacetylfusarinine C into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0039639 suppression by virus of host cell lysis in response to superinfection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039639 lysis inhibition|suppression by virus of host cell lysis in response to superinfecting virus The prevention or delay of host cell lysis by a pre-existing virus in response to a subsequent infection of the host cell by second virus. CHEBI:134339 2-acyl-4-prenylphloroglucinol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134339 GO:0015687 ferric-hydroxamate import into cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015687 ferric-hydroxamate transport A process in which ferric-hydroxamate, the iron-bound form of the iron chelator hydroxamate, is transported into the cell by specific cell surface receptors. GO:0039636 suppression by virus of host cell wall biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039636 Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of cell wall biogenesis in the host organism. Cell wall biogenesis includes the biosynthesis of constituent macromolecules, and the assembly and arrangement of these constituent parts. GO:0039637 catabolism by virus of host DNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039637 The breakdown of host DNA, deoxyribonucleic acid, by a virus. GO:0015688 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015688 GO:0015681 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015681 GO:0015682 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015682 GO:0015683 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015683 GO:0015684 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015684 GO:1990347 obsolete G*/A mismatch-specific adenine-DNA glycosylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990347 G*/A mismatch-specific adenine-DNA glycosylase activity OBSOLETE. Catalysis of the removal of adenine misinserted into nascent strand opposite 8-oxoG in the template by adenine DNA glycosylase activity. The reaction leaves an apyrimidinic (AP) site. GO:0039630 RNA translocase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0039630 Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive movement along a single- or double-stranded RNA molecule. GO:1990348 obsolete G/A mismatch specific adenine DNA glycosylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990348 G/A mismatch specific adenine DNA glycosylase activity OBSOLETE. Catalysis of the removal of adenine misinserted into nascent strand opposite guanine in the template by adenine DNA glycosylase activity. The reaction leaves an apurinic AP site. I also requested same term but for Go/A mismatch. If you think it is better to make one term for mismatched adenine that is fine by me. GO:0039631 DNA translocase activity involved in viral DNA genome packaging biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0039631 viral DNA packaging motor activity|viral DNA packaging activity Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive movement along a single- or double-stranded DNA molecule, that contributes to the packing of viral DNA into a capsid. BFO:0000141 immaterial entity biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BFO_0000141 GO:1990349 gap junction-mediated intercellular transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990349 The movement of substances between cells via gap junctions. A gap junction is a fine cytoplasmic channel, found in animal cells, that connects the cytoplasm of one cell to that of an adjacent cell, allowing ions and other molecules to pass freely between the two cells. GO:0015680 protein maturation by copper ion transfer biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015680 intracellular copper delivery|intracellular copper ion transport|intracellular copper ion delivery A process that contributes to the delivery of copper ions to a target protein. CHEBI:17709 5'-adenylyl sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17709 CHEBI:17707 glucuronoxylan D-glucuronate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17707 CHEBI:17708 1,6-dihydroxycyclohexa-2,4-dienecarboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17708 CHEBI:17705 N(2)-succinyl-L-arginine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17705 CHEBI:17706 Renilla luciferyl sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17706 CHEBI:17703 26-hydroxycholesterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17703 CHEBI:17704 aspulvinone E biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17704 CHEBI:17701 benzenediol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17701 CHEBI:17702 D-apiitol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17702 CHEBI:17700 undecan-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17700 CHEBI:17729 (S)-norcoclaurine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17729 CHEBI:17727 phorbol 13-butanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17727 CHEBI:17728 S-methyl-L-methionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17728 CHEBI:17725 alpha-N-acetylneuraminyl-(2->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17725 CHEBI:17726 [Glu(-Cys)]n-Gly biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17726 CHEBI:17723 beta-D-galactosyl-1,3-(N-acetyl-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17723 CHEBI:17724 N,N-dimethylglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17724 CHEBI:17721 (S,S,S)-nicotianamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17721 CHEBI:17720 2,3-bisphospho-D-glyceric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17720 GO:1990300 cellulosome binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990300 scaffoldin complex binding Interacting selectively and non-covalently with the cellulosome, an extracellular multi-enzyme complex containing several enzymes aligned on a non-catalytic scaffolding that functions to hydrolyze plant cell wall polysaccharides. GO:1990301 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990301 GO:1990302 Bre1-Rad6 ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990302 IntAct:EBI-9102228 Bre1-Rad6 complex A ubiquitin ligase complex consisting of Bre1 and Rad6 that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. It thereby plays a central role in histone code and gene regulation. It also modulates the formation of double-strand breaks during meiosis. CHEBI:17719 beta-D-glucose 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17719 CHEBI:17716 lactose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17716 CHEBI:17717 sulfoacetaldehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17717 CHEBI:17715 quinoline-2,8-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17715 CHEBI:17712 9H-xanthine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17712 CHEBI:17713 2'-deoxyadenosine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17713 CHEBI:17710 (R)-mevalonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17710 CHEBI:17711 nocardicin A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17711 GO:1990307 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990307 GO:1990308 type-I dockerin domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990308 Interacting selectively and non-covalently with a type-I dockerin domain of a protein. Type-I dockerin domain is the binding partner of type-1 cohesin domain. GO:1990309 type-II dockerin domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990309 Interacting selectively and non-covalently with a type-II dockerin domain of a protein. Type-II dockerin domain is the binding partner of type-II cohesin domain. GO:1990303 UBR1-RAD6 ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990303 IntAct:EBI-9103673 UBR1-RAD6 complex A ubiquitin ligase complex consisting of UBR1 and RAD6 components. It polyubiquitinates proteins containing non-acetylated N-terminal residues causing their subsequent degradation by the proteasome as part of the Ac/N-End Rule pathway. It recognizes non-acetylated N-terminal methionine if it is followed by a hydrophobic residue. Additionally, it acts in an N-end rule independent manner as a component of a novel quality control pathway for proteins synthesized on cytosolic ribosomes. GO:1990304 MUB1-RAD6-UBR2 ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990304 IntAct:EBI-9117531 A ubiquitin ligase complex consisting of MUB1, RAD6 and UBR2 components. It ubiquitinates, and targets for destruction, the RPN4 transcription factor, which upregulates the proteasome genes. The binding of MUB1 may position the RPN4 ubiquitylation site proximal to the Ubiquitin-RAD6 thioester and allow the transfer of Ubiquitin from RAD6 to RPN4. One of its components, MUB1, is a short-lived protein ubiquitinated by the UBR2-RAD6 ubiquitin conjugating enzyme. GO:1990305 RAD6-UBR2 ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990305 IntAct:EBI-9116509 RAD6-UBR2 complex A ubiquitin ligase complex consisting of RAD6 and UBR2 components. It may act in a quality control pathway for proteins synthesized on cytosolic ribosomes. The UBR2 component lacks sequence motifs required for N-end rule degradation. GO:1990306 RSP5-BUL ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990306 IntAct:EBI-9105295|IntAct:EBI-9105217 RSP5-BUL1 complex|RSP5-BUL2 complex A ubiquitin ligase complex consisting of RSP5 and BUL components. It polyubiquinates plasma membrane transporters and permeases, required for their endocytosis and subsequent degradation in the vacuole. BUL1 or BUL2, respectively, bind to the target protein, enabling ubiquitylation by Rsp5. Phosphorylation of BUL proteins results in binding to 14-3-3 proteins, protecting the permeases from down-regulation. NCBITaxon:5820 Plasmodium organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_5820 NCBITaxon:5819 Haemosporida organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_5819 Haemospororida|Haemosporina|haemosporidians GO:0050147 nucleoside ribosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050147 MetaCyc:NUCLEOSIDE-RIBOSYLTRANSFERASE-RXN|EC:2.4.2.5 nucleoside:purine(pyrimidine) D-ribosyltransferase activity|nucleoside N-ribosyltransferase activity Catalysis of the reaction: D-ribosyl-base1 + base2 = D-ribosyl-base2 + base1. CHEBI:27119 trihydroxytoluene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27119 GO:0050148 nucleotide diphosphokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050148 RHEA:12713|EC:2.7.6.4|MetaCyc:NUCLEOTIDE-PYROPHOSPHOKINASE-RXN ATP:nucleotide pyrophosphotransferase activity|nucleotide pyrophosphokinase activity|ATP nucleotide 3'-pyrophosphokinase activity|nucleotide 3'-pyrophosphokinase activity|ATP:nucleoside-5'-phosphate diphosphotransferase activity Catalysis of the reaction: ATP + nucleoside 5'-phosphate = AMP + 5'-phosphonucleoside 3'-diphosphate. GO:0050145 nucleoside monophosphate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050145 Reactome:R-HSA-75125|MetaCyc:NUCLEOSIDE-PHOSPHATE-KINASE-RXN|Reactome:R-HSA-6788798|Reactome:R-HSA-6788810|Reactome:R-HSA-73635|EC:2.7.4.4|RHEA:24036|Reactome:R-HSA-2162092|Reactome:R-HSA-75126|Reactome:R-HSA-73548 nucleotide kinase activity|NMP-kinase activity|nucleoside-phosphate kinase activity|nucleoside monophosphate kinase activity|ATP:nucleoside-phosphate phosphotransferase activity Catalysis of the reaction: ATP + nucleoside monophosphate = ADP + nucleoside diphosphate. GO:0050146 nucleoside phosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050146 MetaCyc:NUCLEOSIDE-PHOSPHOTRANSFERASE-RXN|Reactome:R-HSA-2162066|EC:2.7.1.77|RHEA:19961 nucleotide:3'-deoxynucleoside 5'-phosphotransferase activity|nonspecific nucleoside phosphotransferase activity|nucleotide:nucleoside 5'-phosphotransferase activity|nucleotide:2'-nucleoside 5'-phosphotransferase activity Catalysis of the reaction: a nucleotide + a 2'-deoxynucleoside = a nucleoside + a 2'-deoxynucleoside 5'-monophosphate. CHEBI:27115 trihydroxybenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27115 CHEBI:27116 trihydroxyflavone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27116 GO:0050149 o-aminophenol oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050149 RHEA:40963|MetaCyc:O-AMINOPHENOL-OXIDASE-RXN|EC:1.10.3.4 isophenoxazine synthase activity|GriF|o-aminophenol:O2 oxidoreductase activity|2-aminophenol:O2 oxidoreductase activity|2-aminophenol:oxygen oxidoreductase activity Catalysis of the reaction: 2 2-aminophenol + 3 O2 = 2 isophenoxazine + 6 H2O. CHEBI:27118 naphthalenetriol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27118 GO:0015818 isoleucine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015818 L-isoleucine transport The directed movement of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CL:0000644 Bergmann glial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000644 Bergmann astrocyte|Bergmann glial cell of cerebellum Type of radial astrocyte in the cerebellar cortex that have their cell bodies in the Purkinje cell layer and processes that extend into the molecular layer, terminating with bulbous endfeet at the pial surface. Bergmann glia express high densities of glutamate transporters that limit diffusion of the neurotransmitter glutamate during its release from synaptic terminals. Besides their role in early development of the cerebellum, Bergmann glia are also required for the pruning or addition of synapses. GO:0015819 lysine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015819 lysine import|L-lysine import|lysine uptake|L-lysine transport The directed movement of lysine, 2,6-diaminohexanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CL:0000646 basal cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000646 Undifferentiated; mitotic stem cell for other epithelial cell types; rounded or elliptical with little cytoplasm and few organelles; contain cytokeratin intermediate filament. CL:0000647 multinucleated giant cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000647 foreign body giant cell|macrophage polykaryon|multinucleate giant cell|Langerhans giant cell|syncytial giant cell A phagocytic cell formed by the fusion of macrophages, occurs in chronic inflammatory responses to persistent microorganism such as M.tuberculosis, component of granulomas. Sometimes used to refer to megakaryocytes. CHEBI:27114 trihydroxy-5beta-cholanic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27114 CL:0000648 kidney granular cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000648 renin secreting cell|JG cell|juxtaglomerular cell A smooth muscle cell that synthesizes, stores, and secretes the enzyme renin. This cell type are located in the wall of the afferent arteriole at the entrance to the glomerulus. While having a different origin than other kidney smooth muscle cells, this cell type expresses smooth muscle actin upon maturation. GO:0015814 p-aminobenzoyl-glutamate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015814 The directed movement of p-aminobenzoyl-glutamate, the anion of p-aminobenzoyl-glutamic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UBERON:0010543 acropodial skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010543 acropodial skeleton|set of phalanges|skeletal parts of acropodium|skeleton of digits|acropodium|acropodium skeleton|digital skeleton|phalangeal skeleton|skeletal parts of acropodial region|digits skeleton The subdivision of the skeleton that consists of all the skeletal elements at the distalmost end of the autopodium - i.e. the bones of the digits or their cartilaginous precursors[VSAO,modified]. GO:0015815 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015815 GO:0015816 glycine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015816 The directed movement of glycine, aminoethanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UBERON:0010540 tarsus pre-cartilage condensation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010540 A pre-cartilage condensation that has the potential to develop into a tarsal bone. UBERON:0010541 tarsus cartilage element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010541 A cartilaginous condensation that has the potential to develop into a tarsal bone. GO:0015817 histidine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015817 L-histidine transport The directed movement of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:76081 2'-phospho-cyclic ADP-ribose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76081 GO:0015810 aspartate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015810 mitochondrial aspartate/glutamate transport|aspartate transport The process in which aspartate is transported across a lipid bilayer, from one side of a membrane to the other. UBERON:0010535 primitive metanephric nephron biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010535 primitive metanephric nephron|developing metanephric nephron|primitive nephron A primitive nephron that is part of a metanephros. UBERON:0010536 nephron progenitor biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010536 GO:0015811 L-cystine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015811 The directed movement of L-cystine (also known as dicysteine) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UBERON:0009559 metacarpal/tarsal-phalangeal joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009559 metapodium-phalanx joint|metacarpo-tarsophalangeal joint|fetlock|metapodial-phalangeal joint A skeletal joint that connects a mesopodium bone and connects a proximal phalanx. GO:0015812 gamma-aminobutyric acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015812 4-aminobutanoate transport|4-aminobutyrate transport|GABA transport The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UBERON:0010533 metanephros cortex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010533 The metanephric cortex is the outer region of the metanephros[GO]. UBERON:0010534 primitive mesonephric nephron biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010534 primitive mesonephric nephron|developing mesonephric nephron Anatomical cluster which give rise to mature mesonephric nephrons. Zebrafish continously generate new mesonephric nephrons. GO:0015813 L-glutamate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015813 mitochondrial aspartate/glutamate transport|L-glutamate transport The directed movement of L-glutamate across a membrane. CHEBI:76080 1-O-arachidonoyl-N-acetylsphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76080 CHEBI:76085 2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76085 CHEBI:17789 dihydrochelirubine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17789 CHEBI:76086 1-O-linoleoyl-N-acetylsphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76086 CHEBI:76083 oleoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76083 UBERON:0010537 mesonephric nephron progenitor biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010537 Cluster of cells comprising a portion of tissue which gives rise to new mesonephric nephrons. The cluster contains self-renewing stem cells. CHEBI:76084 2-linoleoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76084 UBERON:0010538 paired limb/fin segment biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010538 limb/fin segment An appendage segment that is part of a limb/fin. GO:0050140 nitrate reductase (cytochrome) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050140 EC:1.9.6.1|MetaCyc:NITRATE-REDUCTASE-CYTOCHROME-RXN|RHEA:12909 ferrocytochrome:nitrate oxidoreductase activity|benzyl viologen-nitrate reductase activity Catalysis of the reaction: ferrocytochrome + nitrate = ferricytochrome + nitrite. UBERON:0009550 endoderm of foregut-midgut junction biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009550 An endoderm that is part of a foregut-midgut junction. CHEBI:17786 N-acetyl-L-leucine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17786 CHEBI:76087 1-O-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-N-acetylsphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76087 UBERON:0009551 distal segment of digit biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009551 distal digit segment|tip of digit|digit tip A segment of a digit containing the distal phalanx, and overlapping the distal interphalangeal joint[CJM]. The digit tip is derived from multiple and distinct embryonic origins, and includes the distal bone with associated marrow cavity and haematopoietic cells, ventral (flexor) and dorsal (extensor) tendons, sweat glands with myoepithelial and luminal secreting cells and associated neurons for innervation, dermis with resident melanocytes and dendritic cells, mesenchyme with resident fibroblasts, skin epidermis with hair follicles, a nail organ composed of six specific parts (the root, nail bed, nail plate, eponychium (cuticle), perionychium and hyponychium). UBERON:0009552 distal segment of manual digit biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009552 finger tip|finger distal segment|forelimb digit tip|fingertip|finger digit tip|tip of finger A segment of the manual digit containing the distal phalanx CHEBI:76088 2-oleoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76088 CHEBI:17784 2-amino-2-deoxy-D-gluconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17784 UBERON:0009553 distal segment of pedal digit biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009553 P3 segment of pedal digit|distalmost part of toe|toe distal segment|toe digit tip|hindlimb digit tip|tip of toe A segment of the pedal digit containing the distal phalanx. Note this class represents a digit segment and thus includes tissues in addition to bone. GO:0050143 nocardicin-A epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050143 EC:5.1.1.14|RHEA:22792|KEGG_REACTION:R03073|MetaCyc:NOCARDICIN-A-EPIMERASE-RXN isonocardicin A epimerase activity Catalysis of the reaction: isonocardicin A = nocardicin A. CHEBI:17781 lumichrome biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17781 GO:0050144 nucleoside deoxyribosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050144 EC:2.4.2.6|MetaCyc:NUCLEOSIDE-DEOXYRIBOSYLTRANSFERASE-RXN purine(pyrimidine) nucleoside:purine(pyrimidine) deoxyribosyl transferase activity|trans-deoxyribosylase activity|trans-N-deoxyribosylase activity|nucleoside deoxyribosyltransferase II [purine(pyrimidine) nucleoside:purine(pyrimidine) deoxyribosyltransferase]|trans-N-glycosidase activity|nucleoside:purine(pyrimidine) deoxy-D-ribosyltransferase activity|nucleoside deoxyribosyltransferase I (purine nucleoside:purine deoxyribosyltransferase: strictly specific for transfer between purine bases)|nucleoside trans-N-deoxyribosylase activity|deoxyribose transferase activity Catalysis of the reaction: 2-deoxy-D-ribosyl-base1 + base2 = 2-deoxy-D-ribosyl-base2 + base1. CHEBI:17782 5-dehydro-4-deoxy-D-glucuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17782 GO:0050141 nitroethane oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050141 EC:1.7.3.1|MetaCyc:NITROETHANE-OXIDASE-RXN nitroethane:oxygen oxidoreductase activity|nitroethane reductase activity Catalysis of the reaction: nitroethane + H2O + O2 = acetaldehyde + nitrite + H2O2. CHEBI:17780 5-hydroxy-L-tryptophan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17780 GO:0050142 nitrogenase (flavodoxin) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050142 EC:1.19.6.1|RHEA:15645|MetaCyc:NITROGENASE-FLAVODOXIN-RXN reduced flavodoxin:dinitrogen oxidoreductase (ATP-hydrolysing) Catalysis of the reaction: 6 reduced flavodoxin + 6 H+ + N2 + n ATP = 6 oxidized flavodoxin + 2 NH3 + n ADP + n phosphate. GO:0050158 orotate reductase (NADPH) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050158 RHEA:14861|MetaCyc:OROTATE-REDUCTASE-NADPH-RXN|EC:1.3.1.15|KEGG_REACTION:R01866 L-5,6-dihydro-orotate:NAD oxidoreductase activity|orotate reductase activity|(S)-dihydroorotate:NADP+ oxidoreductase activity|dihydro-orotic dehydrogenase activity Catalysis of the reaction: (S)-dihydroorotate + NADP(+) = H(+) + NADPH + orotate. GO:0050159 orsellinate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050159 RHEA:16733|MetaCyc:ORSELLINATE-DECARBOXYLASE-RXN|EC:4.1.1.58|KEGG_REACTION:R02831 orsellinate carboxy-lyase (orcinol-forming)|orsellinate carboxy-lyase activity Catalysis of the reaction: o-orsellinate + H(+) = CO(2) + orcinol. GO:0050156 ornithine N-benzoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050156 EC:2.3.1.127|MetaCyc:ORNITHINE-N-BENZOYLTRANSFERASE-RXN|RHEA:16929|KEGG_REACTION:R00664 ornithine N-acyltransferase activity|benzoyl-CoA:L-ornithine N-benzoyltransferase activity Catalysis of the reaction: L-ornithine + 2 benzoyl-CoA = N(2),N(5)-dibenzoyl-L-ornithine + 2 CoA + 2 H(+). GO:0050157 ornithine racemase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050157 RHEA:11584|MetaCyc:ORNITHINE-RACEMASE-RXN|EC:5.1.1.12 Catalysis of the reaction: L-ornithine = D-ornithine. NCBITaxon:5878 Ciliophora organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_5878 Ciliata|ciliates|ciliates GO:0015829 valine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015829 L-valine transport The directed movement of valine, 2-amino-3-methylbutanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CL:0000655 secondary oocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000655 primary oogonium A secondary oocyte is an oocyte that has not completed meiosis II. CL:0000656 primary spermatocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000656 A diploid cell that has derived from a spermatogonium and can subsequently begin meiosis and divide into two haploid secondary spermatocytes. CL:0000657 secondary spermatocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000657 One of the two haploid cells into which a primary spermatocyte divides, and which in turn gives origin to spermatids. CHEBI:27124 trimethoxyflavone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27124 UBERON:0010531 metanephros induced blastemal cells biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010531 cap mesenchyme of metanephros of urinary system|induced blastemal cells|peripheral blastema|nephrogenic interstitium|nephrogenic interstitium of nephrogenic zone . GO:0015825 L-serine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015825 L-serine import The directed movement of L-serine, the L-enantiomer of 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UBERON:0010532 primitive nephron biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010532 presumptive nephron|future nephron|primitive nephron|developing nephron An epithelial tube that is fated to become a nephron. GO:0015826 threonine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015826 L-threonine transport The directed movement of threonine, (2R*,3S*)-2-amino-3-hydroxybutanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015827 tryptophan transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015827 L-tryptophan transport The directed movement of tryptophan, 2-amino-3-(1H-indol-3-yl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:27120 triihydroxypyridine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27120 GO:0015828 tyrosine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015828 L-tyrosine transport The directed movement of tyrosine, 2-amino-3-(4-hydroxyphenyl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015821 methionine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015821 L-methionine transport The directed movement of methionine, 2-amino-4-(methylthio)butanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015822 ornithine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015822 L-ornithine transport The directed movement of ornithine, 2,5-diaminopentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UBERON:0009548 hepatic sinusoid of left of lobe of liver biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009548 left lobe hepatic sinusoids A hepatic sinusoid that is part of a left lobe of liver. UBERON:0010522 replacement element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010522 Skeletal element that forms as a replacement or substitution of another element or tissue. GO:0015823 phenylalanine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015823 L-phenylalanine transport The directed movement of phenylalanine, 2-amino-3-phenylpropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:76090 2-linoleoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76090 CL:0000650 mesangial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000650 kidney mesangial cell A cell type that encapsulates the capillaries and venules in the kidney. This cell secretes mesangial matrix that provides the structural support for the capillaries. UBERON:0010523 microcirculatory vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010523 microcirculatory vessels A vessel of the microcirculature, lying between the arterioles and venules; includes capillaries (blood and lymphatic), metarterioles and arteriovenous anastomoses. GO:0015824 proline transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015824 L-proline transport The directed movement of proline, pyrrolidine-2-carboxylic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UBERON:0009549 hepatic sinusoid of right of lobe of liver biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009549 right lobe hepatic sinusoids A hepatic sinusoid that is part of a right lobe of liver. CHEBI:76091 2-arachidonoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76091 UBERON:0010528 pneumatic cavity of bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010528 air space of bone CHEBI:17778 2-hydroxy-3-oxosuccinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17778 CL:0000653 glomerular visceral epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000653 epithelial cell of visceral layer of glomerular capsule|glomerular podocyte|podocyte A glomerular visceral epithelial cell is a specialized kidney epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells. GO:0015820 leucine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015820 L-leucine transport The directed movement of leucine, 2-amino-4-methylpentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UBERON:0010527 cavity of bone organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010527 bone organ cavity An organ cavity that surrounded_by a bone. CL:0000654 primary oocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000654 primary oogonium A primary oocyte is an oocyte that has not completed female meosis I. GO:0050150 o-pyrocatechuate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050150 MetaCyc:O-PYROCATECHUATE-DECARBOXYLASE-RXN|UM-BBD_reactionID:r0579|EC:4.1.1.46|KEGG_REACTION:R00821|RHEA:21492 2,3-dihydroxybenzoic acid decarboxylase activity|2,3-dihydroxybenzoate carboxy-lyase activity|2,3-dihydroxybenzoate decarboxylase activity|2,3-dihydroxybenzoate carboxy-lyase (catechol-forming)|2,3-DHBA decarboxylase activity Catalysis of the reaction: 2,3-dihydroxybenzoate + H(+) = catechol + CO(2). CHEBI:17774 pimelate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17774 GO:0050151 oleate hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050151 KEGG_REACTION:R02813|RHEA:21852|EC:4.2.1.53|MetaCyc:OLEATE-HYDRATASE-RXN (R)-10-hydroxystearate 10-hydro-lyase activity|(R)-10-hydroxystearate 10-hydro-lyase (oleate-forming) Catalysis of the reaction: (R)-10-hydroxystearate = H(2)O + oleate. CHEBI:17775 7,9-dihydro-1H-purine-2,6,8(3H)-trione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17775 CHEBI:17772 (S)-tetrahydrocolumbamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17772 CHEBI:17773 D-ribonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17773 CHEBI:76099 phenyl 5-phosphono-alpha-D-ribofuranoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76099 GO:0050154 opheline kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050154 MetaCyc:OPHELINE-KINASE-RXN|RHEA:17553|EC:2.7.3.7|KEGG_REACTION:R04388 ATP:guanidinoethyl-methyl-phosphate phosphotransferase activity Catalysis of the reaction: ATP + guanidinoethyl methyl phosphate = N'-phosphoguanidinoethyl methylphosphate + ADP + 2 H(+). CHEBI:17770 1-hydroxy-2-(beta-D-glucosyloxy)-9,10-anthraquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17770 GO:0050155 ornithine(lysine) transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050155 MetaCyc:ORNITHINELYSINE-AMINOTRANSFERASE-RXN|EC:2.6.1.13 ornithine(lysine) aminotransferase activity|lysine/ornithine:2-oxoglutarate aminotransferase activity|L-ornithine:2-oxoglutarate-aminotransferase activity|L-ornithine(L-lysine):2-oxoglutarate-aminotransferase activity Catalysis of the reaction: 2-oxoglutarate + L-ornithine = H2O + L-glutamate + 3,4-dihydro-2H-pyrrole-2-carboxylate. CHEBI:17771 trans-urocanate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17771 GO:0050152 omega-amidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050152 EC:3.5.1.3|RHEA:11716|MetaCyc:OMEGA-AMIDASE-RXN w-amidase activity|omega-amidodicarboxylate amidohydrolase activity|alpha-keto acid-omega-amidase activity Catalysis of the reaction: a monoamide of a dicarboxylic acid + H2O = a dicarboxylate + NH3. GO:0050153 omega-hydroxydecanoate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050153 MetaCyc:OMEGA-HYDROXYDECANOATE-DEHYDROGENASE-RXN|EC:1.1.1.66|KEGG_REACTION:R03886|RHEA:20880 w-hydroxydecanoate dehydrogenase activity|10-hydroxydecanoate:NAD+ 10-oxidoreductase activity Catalysis of the reaction: 10-hydroxydecanoate + NAD(+) = 10-oxodecanoate + H(+) + NADH. GO:0050169 peptide-tryptophan 2,3-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050169 MetaCyc:PEPTIDE-TRYPTOPHAN-23-DIOXYGENASE-RXN|EC:1.13.11.26 pyrrolooxygenase activity|peptide-tryptophan:oxygen 2,3-oxidoreductase (decyclizing)|tryptophan pyrrolooxygenase activity|peptidyltryptophan 2,3-dioxygenase activity Catalysis of the reaction: peptide tryptophan + O2 = peptide formylkynurenine. GO:0050167 pantothenoylcysteine decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050167 EC:4.1.1.30|KEGG_REACTION:R02972|MetaCyc:PANTOTHENOYLCYSTEINE-DECARBOXYLASE-RXN|RHEA:15077 N-[(R)-pantothenoyl]-L-cysteine carboxy-lyase (pantetheine-forming)|pantothenylcysteine decarboxylase activity|N-[(R)-pantothenoyl]-L-cysteine carboxy-lyase activity|N-((R)-pantothenoyl)-L-cysteine carboxy-lyase activity Catalysis of the reaction: N-[(R)-pantothenoyl]-L-cysteine + H(+) = (R)-pantetheine + CO(2). GO:0050168 pentanamidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050168 KEGG_REACTION:R02938|MetaCyc:PENTANAMIDASE-RXN|RHEA:10000|EC:3.5.1.50 valeramidase activity|pentanamide amidohydrolase activity Catalysis of the reaction: H(2)O + pentanamide = NH(4)(+) + valerate. CL:0000622 acinar cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000622 acinous cell|acinic cell A secretory cell that is grouped together with other cells of the same type to form grape shaped clusters known as acini (singular acinus). CL:0000623 natural killer cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000623 null cell|large granular lymphocyte|NK cell A lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors and also regulate immune responses via cytokine release and direct contact with other cells. CL:0000624 CD4-positive, alpha-beta T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000624 CD4-positive, alpha-beta T-cell|CD4-positive, alpha-beta T-lymphocyte|CD4-positive, alpha-beta T lymphocyte A mature alpha-beta T cell that expresses an alpha-beta T cell receptor and the CD4 coreceptor. CL:0000625 CD8-positive, alpha-beta T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000625 CD8-positive, alpha-beta T-cell|CD8-positive, alpha-beta T-lymphocyte|CD8-positive, alpha-beta T lymphocyte A T cell expressing an alpha-beta T cell receptor and the CD8 coreceptor. CL:0000626 olfactory granule cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000626 Granule cell that is part of the olfactory bulb. UBERON:0010521 electroreceptor organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010521 electric sense organ|electroreception organ An organ that is capable of detecting electrical stimulus UBERON:0009536 vascular element of left lung biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009536 A vascular plexus that is part of a left lung. UBERON:0009537 vascular element of right lung biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009537 A vascular plexus that is part of a right lung. UBERON:0009539 mesenchyme of submandibular gland primordium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009539 submaxillary gland primordium mesenchyme Mesenchyme that is part of a submandibular gland primordium. GO:0050161 succinyl-CoA:oxalate CoA-transferase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050161 KEGG_REACTION:R01559|RHEA:23588|MetaCyc:OXALATE-COA-TRANSFERASE-RXN|EC:2.8.3.2 succinyl-beta-ketoacyl-CoA transferase activity|oxalate coenzyme A-transferase activity|oxalate CoA-transferase activity|succinyl-CoA:oxalate CoA-transferase activity Catalysis of the reaction: oxalate + succinyl-CoA = oxalyl-CoA + succinate. GO:0050162 oxalate oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050162 RHEA:21881|MetaCyc:OXALATE-OXIDASE-RXN|KEGG_REACTION:R00273|EC:1.2.3.4 oxalate:oxygen oxidoreductase activity|oxalic acid oxidase activity|aero-oxalo dehydrogenase activity Catalysis of the reaction: 2 H(+) + O(2) + oxalate = 2 CO(2) + H(2)O(2). GO:0050160 orsellinate-depside hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050160 EC:3.1.1.40|RHEA:19549|KEGG_REACTION:R00054|MetaCyc:ORSELLINATE-DEPSIDE-HYDROLASE-RXN lecanorate hydrolase activity Catalysis of the reaction: H(2)O + orsellinate depside = 2 o-orsellinate + H(+). GO:0050165 pantetheine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050165 EC:2.7.1.34|RHEA:22472|MetaCyc:PANTETHEINE-KINASE-RXN pantetheine kinase (phosphorylating)|ATP:pantetheine 4'-phosphotransferase activity Catalysis of the reaction: ATP + pantetheine = ADP + pantetheine 4'-phosphate. GO:0050166 pantoate 4-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050166 MetaCyc:PANTOATE-4-DEHYDROGENASE-RXN|RHEA:23000|KEGG_REACTION:R02471|EC:1.1.1.106 (R)-pantoate:NAD+ 4-oxidoreductase activity|pantoate dehydrogenase activity|panthothenase activity|D-pantoate:NAD+ 4-oxidoreductase activity Catalysis of the reaction: (R)-pantoate + NAD(+) = (R)-4-dehydropantoate + H(+) + NADH. GO:0050163 oxaloacetate tautomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050163 KEGG_REACTION:R00363|EC:5.3.2.2|RHEA:16021|MetaCyc:OXALOACETATE-TAUTOMERASE-RXN oxaloacetate keto-enol tautomerase activity|oxaloacetate keto-enol-isomerase activity|oxalacetic keto-enol isomerase activity Catalysis of the reaction: oxaloacetate = enol-oxaloacetate. GO:0050164 oxoglutarate dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050164 EC:1.2.1.52|RHEA:21400|KEGG_REACTION:R00265|MetaCyc:OXOGLUTARATE-DEHYDROGENASE-NADP+-RXN 2-oxoglutarate:NADP+ 2-oxidoreductase (CoA-succinylating) Catalysis of the reaction: 2-oxoglutarate + CoA + NADP(+) = CO(2) + NADPH + succinyl-CoA. GO:0050178 phenylpyruvate tautomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050178 EC:5.3.2.1|RHEA:17097|MetaCyc:PHENYLPYRUVATE-TAUTOMERASE-RXN phenylpyruvate keto--enol tautomerase activity|phenylpyruvic keto--enol isomerase activity|phenylpyruvate keto-enol-isomerase activity Catalysis of the reaction: keto-phenylpyruvate = enol-phenylpyruvate. GO:0050179 phenylserine aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050179 MetaCyc:PHENYLSERINE-ALDOLASE-RXN|EC:4.1.2.26|RHEA:21712|KEGG_REACTION:R01766 L-threo-3-phenylserine benzaldehyde-lyase (glycine-forming)|L-threo-3-phenylserine benzaldehyde-lyase activity Catalysis of the reaction: L-threo-3-phenylserine = benzaldehyde + glycine. CHEBI:27105 tridecadienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27105 GO:0015807 L-amino acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015807 The directed movement of L-enantiomer amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015808 L-alanine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015808 The directed movement of L-alanine, the L-enantiomer of 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015809 arginine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015809 L-arginine transport The directed movement of arginine, 2-amino-5-guanidinopentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:27102 trichlorophenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27102 GO:0015803 branched-chain amino acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015803 branched-chain amino-acid anion transport|branched-chain amino-acid anions transport|branched-chain aliphatic amino acid transport The directed movement of branched-chain amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Branched-chain amino acids are amino acids with a branched carbon skeleton without rings. CL:0000637 chromophil cell of anterior pituitary gland biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000637 A cell that stains readily in the anterior pituitary gland. GO:0015804 neutral amino acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015804 The directed movement of neutral amino acids, amino acids with no net charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CL:0000639 basophil cell of pars distalis of adenohypophysis biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000639 pituitary beta cell|basophil cell of anterior lobe of hypophysis|beta cell A basophillic chromophil cell that of the anterior pituitary gland. GO:0015805 S-adenosyl-L-methionine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015805 S-adenosylmethionine transport|SAM transport|S-adenosyl methionine transport The directed movement of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015806 S-methylmethionine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015806 The directed movement of S-methylmethionine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015800 acidic amino acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015800 The directed movement of acidic amino acids, amino acids with a pH below 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UBERON:0009526 maxillary process mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009526 mesenchyme of maxillary process|mesenchyme of maxillary prominence Mesenchyme that is part of a maxillary prominence. GO:0015801 aromatic amino acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015801 The directed movement of aromatic amino acids, amino acids with aromatic ring, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015802 basic amino acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015802 The directed movement of basic amino acids, amino acids with a pH above 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:42724 (R)-amphetamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_42724 CL:0000630 supportive cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000630 A cell whose primary function is to support other cell types. CHEBI:17798 L-gamma-glutamyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17798 CL:0000632 hepatic stellate cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000632 lipocyte|Ito cell|perisinusoidal cell|hepatic perisinusoidal cell|fat-storing cell|vitamin A-storing cells A cell that is found in the perisinusoidal space of the liver that is capable of multiple roles including storage of retinol, presentation of antigen to T cells (including CD1d-restricted NKT cells), and upon activation, production of extracellular matrix components that can contribute to liver fibrosis. This activated state has a myofibroblast-like phenotype, though it's not clear in the literature if this is terminally differentiated. This cell type comprises approximately 8-15% of total cells in the liver. CHEBI:17799 2-methyl-DL-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17799 GO:0050172 phenylalanine 2-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050172 EC:1.13.12.9|RHEA:10712|KEGG_REACTION:R00690|MetaCyc:PHENYLALANINE-2-MONOOXYGENASE-RXN L-phenylalanine:oxygen 2-oxidoreductase (decarboxylating)|l-phenylalanine oxidase (deaminating and decarboxylating) activity|phenylalanine (deaminating, decarboxylating) oxidase activity|L-phenylalanine oxidase (deaminating and decarboxylating)|phenylalanine (deaminating, decarboxylating)oxidase activity Catalysis of the reaction: L-phenylalanine + O(2) = 2-phenylacetamide + CO(2) + H(2)O. CHEBI:17796 L-idonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17796 GO:0050173 phenylalanine adenylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050173 KEGG_REACTION:R00687|MetaCyc:PHENYLALANINE-ADENYLYLTRANSFERASE-RXN|EC:2.7.7.54|RHEA:17189 ATP:phenylalanine adenylyltransferase activity|L-phenylalanine adenylyltransferase activity|ATP:L-phenylalanine adenylyltransferase activity Catalysis of the reaction: L-phenylalanine + ATP = N-adenylyl-L-phenylalanine + diphosphate + 2 H(+). CHEBI:17797 aldehydo-D-ribose 5-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17797 NCBITaxon:88770 Panarthropoda organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_88770 GO:0050170 peptidyl-glutaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050170 EC:3.5.1.43|RHEA:10032|MetaCyc:PEPTIDYL-GLUTAMINASE-RXN peptideglutaminase activity|peptidoglutaminase I activity|peptidoglutaminase activity|peptidyl-L-glutamine amidohydrolase activity Catalysis of the reaction: alpha-N-peptidyl-L-glutamine + H2O = alpha-N-peptidyl-L-glutamate + NH3. CHEBI:17794 3-phospho-D-glyceric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17794 GO:0050171 phenol beta-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050171 MetaCyc:PHENOL-BETA-GLUCOSYLTRANSFERASE-RXN|EC:2.4.1.35 phenol-beta-D-glucosyltransferase activity|UDPglucose:phenol beta-D-glucosyltransferase activity|phenol b-glucosyltransferase activity|UDPglucosyltransferase activity|UDP glucosyltransferase activity|uridine diphosphoglucosyltransferase activity|UDP-glucose glucosyltransferase activity|UDP-glucose:phenol beta-D-glucosyltransferase activity Catalysis of the reaction: UDP-glucose + a phenol = UDP + an aryl beta-D-glucoside. CHEBI:17795 dihydroxyfumarate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17795 GO:0050176 phenylalanine N-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050176 MetaCyc:PHENYLALANINE-N-ACETYLTRANSFERASE-RXN|EC:2.3.1.53|RHEA:17801|KEGG_REACTION:R00693 acetyl-CoA-L-phenylalanine alpha-N-acetyltransferase activity|acetyl-CoA:L-phenylalanine N-acetyltransferase activity Catalysis of the reaction: L-phenylalanine + acetyl-CoA = N-acetyl-L-phenylalanine + CoA + H(+). CHEBI:17792 organohalogen compound biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17792 GO:0050177 phenylpyruvate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050177 MetaCyc:PHENYLPYRUVATE-DECARBOXYLASE-RXN|RHEA:14185|EC:4.1.1.43 phenylpyruvate carboxy-lyase activity|phenylpyruvate carboxy-lyase (phenylacetaldehyde-forming) Catalysis of the reaction: phenylpyruvate = phenylacetaldehyde + CO2. UBERON:0009521 anal membrane endodermal component biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009521 An endoderm that is part of a anal region. CHEBI:17793 calycosin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17793 UBERON:0009522 lateral lingual swelling epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009522 An epithelium that is part of a lateral lingual swelling. CHEBI:17790 methanol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17790 GO:0050174 phenylalanine decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050174 MetaCyc:PHENYLALANINE-DECARBOXYLASE-RXN|EC:4.1.1.53|RHEA:19717 L-phenylalanine carboxy-lyase activity|aromatic L-amino acid decarboxylase activity|L-phenylalanine decarboxylase activity|L-phenylalanine carboxy-lyase (phenylethylamine-forming) Catalysis of the reaction: L-phenylalanine = phenylethylamine + CO2. GO:0050175 phenylalanine dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050175 MetaCyc:PHENYLALANINE-DEHYDROGENASE-RXN|RHEA:21408|EC:1.4.1.20 L-phenylalanine:NAD+ oxidoreductase (deaminating)|PheDH activity|PHD|L-phenylalanine dehydrogenase activity Catalysis of the reaction: L-phenylalanine + H2O + NAD+ = phenylpyruvate + NH3 + NADH. UBERON:0009523 mesenchyme of handplate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009523 hand plate mesenchyme|handplate mesenchyme Mesenchyme that is part of a handplate. CHEBI:17791 obtusifoliol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17791 CL:0000608 zygospore biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000608 A thick walled, sexual, resting spore formed by Zygomycetes; sometimes refers to the spore and the multi-layered cell wall that encloses the spore, the zygosporangium. CL:0000609 vestibular hair cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000609 vestibular receptor cell A mechanoreceptor located in the acoustic maculae and the semicircular canals that mediates the sense of balance, movement, and head position. The vestibular hair cells are connected to accessory structures in such a way that movements of the head displace their stereocilia. This influences the membrane potential of the cells which relay information about movements via the vestibular part of the vestibulocochlear nerve to the brain stem. GO:0050189 phosphoenolpyruvate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050189 KEGG_REACTION:R00208|MetaCyc:PHOSPHOENOLPYRUVATE-PHOSPHATASE-RXN|EC:3.1.3.60|RHEA:19997 PEP phosphatase activity|phosphoenolpyruvate phosphohydrolase activity Catalysis of the reaction: H(2)O + phosphoenolpyruvate = phosphate + pyruvate. CL:0000601 outer hair cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000601 cochlear outer hair cell A mechanoreceptor in the organ of Corti. In mammals the outer hair cells are arranged in three rows which are further from the modiolus than the single row of inner hair cells. The motile properties of the outer hair cells may contribute actively to tuning the sensitivity and frequency selectivity of the cochlea. CL:0000604 retinal rod cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000604 One of the two photoreceptor cell types of the vertebrate retina. In rods the photopigment is in stacks of membranous disks separate from the outer cell membrane. Rods are more sensitive to light than cones, but rod mediated vision has less spatial and temporal resolution than cone vision. UBERON:0010586 manual digit phalanx pre-cartilage condensation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010586 fore limb digit phalanx pre-cartilage condensation|forelimb phalanx pre-cartilage condensation|hand phalanx pre-cartilage condensation|hand digit phalanx pre-cartilage condensation|manus phalanx pre-cartilage condensation A pre-cartilage condensation that is part of a manual digit mesenchyme. CL:0000605 fungal asexual spore biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000605 A spore formed following mitosis or mitoses. CL:0000606 macroconidium biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000606 The larger of two types of asexual spores formed by some fungi; usually round or oblong. CL:0000607 ascospore biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000607 A thick walled spore that stores and protects one or more nuclei following sexual reproduction in an Ascomycete. UBERON:0010585 pedal digit phalanx pre-cartilage condensation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010585 pes phalanx pre-cartilage condensation|hind limb digit phalanx pre-cartilage condensation|hindlimb phalanx pre-cartilage condensation|foot phalanx pre-cartilage condensation|foot digit phalanx pre-cartilage condensation A pre-cartilage condensation that is part of a pedal digit mesenchyme. CHEBI:42717 alpha-D-glucuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_42717 CHEBI:17747 bis(2-ethylhexyl) phthalate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17747 CHEBI:17748 thymidine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17748 CHEBI:17745 coniferol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17745 CHEBI:17746 D-xylonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17746 GO:0050180 phloretin hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050180 EC:3.7.1.4|RHEA:23396|MetaCyc:PHLORETIN-HYDROLASE-RXN|KEGG_REACTION:R02901 2',4,4',6'-tetrahydroxydehydrochalcone 1,3,5-trihydroxybenzenehydrolase activity|lactase-phlorizin hydrolase Catalysis of the reaction: H(2)O + phloretin = H(+) + phloretate + phloroglucinol. GO:0050183 phosphatidylcholine 12-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050183 KEGG_REACTION:R03476|RHEA:46360|EC:1.14.18.4|MetaCyc:PHOSPHATIDYLCHOLINE-12-MONOOXYGENASE-RXN ricinoleic acid synthase activity|oleate Delta(12)-hydroxylase activity|oleate delta12-hydroxylase activity|1-acyl-2-oleoyl-sn-glycero-3-phosphocholine,NADH:oxygen oxidoreductase (12-hydroxylating)|oleate delta12-monooxygenase activity|oleate D12-hydroxylase activity Catalysis of the reaction: 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine + H(+) + NADH + O(2) = 1-acyl-2-[(S)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine + H(2)O + NAD(+). CHEBI:17741 N,N-dimethylformamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17741 GO:0050184 phosphatidylcholine desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050184 RHEA:12564|KEGG_REACTION:R03475|MetaCyc:PHOSPHATIDYLCHOLINE-DESATURASE-RXN|EC:1.14.19.22 acyl-lipid omega-6 desaturase (cytochrome b5)|linoleate synthase activity|1-acyl-2-oleoyl-sn-glycero-3-phosphocholine:NAD+ delta12-oxidoreductase activity|oleoylphosphatidylcholine desaturase activity|oleate desaturase activity|oleoyl-CoA desaturase activity Catalysis of the reaction: 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine + NAD(+) = 1-acyl-2-linoleoyl-sn-glycero-3-phosphocholine + H(+) + NADH. CHEBI:17742 4-hydroxy-2-oxoglutarate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17742 GO:0050181 phorbol-diester hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050181 KEGG_REACTION:R04119|EC:3.1.1.51|MetaCyc:PHORBOL-DIESTER-HYDROLASE-RXN|RHEA:21316 diacylphorbate 12-hydrolase activity|12,13-diacylphorbate 12-acylhydrolase activity|PDEH|phorbol-12,13-diester 12-ester hydrolase activity Catalysis of the reaction: H(2)O + phorbol 12,13-dibutanoate = butanoate + H(+) + phorbol 13-butanoate. GO:0050182 phosphate butyryltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050182 RHEA:20892|KEGG_REACTION:R01174|EC:2.3.1.19|MetaCyc:PHOSPHATE-BUTYRYLTRANSFERASE-RXN phosphotransbutyrylase activity|butanoyl-CoA:phosphate butanoyltransferase activity Catalysis of the reaction: butanoyl-CoA + phosphate = butanoyl phosphate + CoA. CHEBI:17740 3-oxoalanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17740 GO:0050187 phosphoamidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050187 RHEA:12977|KEGG_REACTION:R01882|EC:3.9.1.1|MetaCyc:PHOSPHOAMIDASE-RXN phosphamide hydrolase activity|creatine phosphatase activity Catalysis of the reaction: N-phosphocreatine + H(2)O = creatine + phosphate. GO:0050188 phosphoenolpyruvate mutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050188 EC:5.4.2.9|KEGG_REACTION:R00661|RHEA:17013|MetaCyc:PHOSPHOENOLPYRUVATE-MUTASE-RXN PEP phosphomutase activity|phosphoenolpyruvate-phosphonopyruvate phosphomutase activity|phosphoenolpyruvate phosphomutase activity|PEP mutase activity|PEPPM|phosphoenolpyruvate 2,3-phosphonomutase activity Catalysis of the reaction: phosphoenolpyruvate = 3-phosphonopyruvate. GO:0050185 phosphatidylinositol deacylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050185 EC:3.1.1.52|KEGG_REACTION:R03360|MetaCyc:PHOSPHATIDYLINOSITOL-DEACYLASE-RXN|RHEA:18001 1-phosphatidyl-D-myo-inositol 2-acylhydrolase activity|phosphatidylinositol phospholipase A2 activity Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + H(2)O = 1-acyl-sn-glycero-3-phospho-D-myo-inositol + a carboxylate + H(+). GO:0050186 phosphoadenylylsulfatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050186 RHEA:11232|EC:3.6.2.2|MetaCyc:PHOSPHOADENYLYLSULFATASE-RXN 3'-phosphoadenylylsulfate sulfohydrolase activity|3-phosphoadenosine 5-phosphosulfate sulfatase activity|phosphoadenylylsulphatase activity|3-phosphoadenylyl sulfatase activity|PAPS sulfatase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + H2O = adenosine 3',5'-bisphosphate + sulfate. UBERON:0009580 diencephalon mantle layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009580 mantle layer lateral wall diencephalon|diencephalon lateral wall mantle layer UBERON:0009581 midbrain mantle layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009581 midbrain lateral wall mantle layer|mantle layer lateral wall midbrain|mantle layer lateral wall mesencephalon CL:0000611 eosinophil progenitor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000611 eosinophil stem cell|colony forming unit eosinophil|EoP|CFU-Eo CL:0000612 eosinophilic myelocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000612 A eosinophil precursor in the granulocytic series, being a cell intermediate in development between a promyelocyte and a metamyelocyte;in this stage, production of primary granules is complete and eosinophil-specific granules has started. No nucleolus is present. These cells are integrin alpha-M-positive, CD13-positive, CD15-positive, CD16-negative, CD24-positive, and CD33-positive. CL:0000613 basophil progenitor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000613 BaP|colony forming unit basophil|basophilic stem cell|CFU-Bas A progenitor cell committed to the basophil lineage. This cell lacks hematopoietic lineage markers (lin-negative) and is CD34-positive, T1/ST2-low, CD117-negative, and FceRIa-high. This cell also expresses Gata-1, Gata-2 and C/EBPa. CL:0000614 basophilic myelocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000614 A basophil precursor in the granulocytic series, being a cell intermediate in development between a promyelocyte and a metamyelocyte; in this stage, production of primary granules is complete and basophil-specific granules has started. No nucleolus is present. Markers are being integrin alpha-M-positive, fucosyltransferase FUT4-positive, CD33-positive, CD24-positive, aminopeptidase N-positive. CL:0000615 basidiospore biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000615 A thick walled spore containing one or more haploid nuclei produced by sexual reproduction in an Basidiomycete; formed externally on extrusions of the basidium. CL:0000617 GABAergic neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000617 GABA-ergic neuron A neuron that uses GABA as a vesicular neurotransmitter CHEBI:17738 N-methyl-2-oxoglutaramate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17738 CHEBI:17736 S-(4-bromophenyl)-L-cysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17736 CHEBI:17737 desmosterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17737 GO:0050190 phosphoglucokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050190 KEGG_REACTION:R00949|MetaCyc:PHOSPHOGLUCOKINASE-RXN|EC:2.7.1.10|RHEA:13377 ATP:alpha-D-glucose-1-phosphate 6-phosphotransferase activity|phosphoglucokinase (phosphorylating)|glucose-phosphate kinase activity|ATP:D-glucose-1-phosphate 6-phosphotransferase activity Catalysis of the reaction: alpha-D-glucose 1-phosphate + ATP = alpha-D-glucose 1,6-bisphosphate + ADP + 2 H(+). CHEBI:17734 alpha-cyclopiazonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17734 GO:0050191 phosphoglycerate kinase (GTP) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050191 KEGG_REACTION:R01517|MetaCyc:PHOSPHOGLYCERATE-KINASE-GTP-RXN|EC:2.7.2.10|RHEA:23332 GTP:3-phospho-D-glycerate 1-phosphotransferase activity Catalysis of the reaction: 3-phospho-D-glycerate + GTP = 3-phospho-D-glyceroyl phosphate + GDP + H(+). CHEBI:17735 N,N-dimethylaniline N-oxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17735 CHEBI:17732 Ala-tRNA(Ala) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17732 CHEBI:17733 aldehydo-D-galactose 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17733 GO:0050194 phosphonoacetaldehyde hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050194 MetaCyc:PHOSPHONOACETALDEHYDE-HYDROLASE-RXN|EC:3.11.1.1|KEGG_REACTION:R00747|RHEA:18905 phosphonatase activity|2-phosphonoacetylaldehyde phosphonohydrolase activity|phosphonoacetylaldehyde phosphonohydrolase activity|2-oxoethylphosphonate phosphonohydrolase activity Catalysis of the reaction: H(2)O + phosphonoacetaldehyde = acetaldehyde + H(+) + phosphate. CHEBI:17730 quercetin 3-sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17730 GO:0050195 phosphoribokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050195 EC:2.7.1.18|RHEA:21216|MetaCyc:PHOSPHORIBOKINASE-RXN|KEGG_REACTION:R01050 ATP:D-ribose-5-phosphate 1-phosphotransferase activity|phosphoribokinase (phosphorylating) Catalysis of the reaction: D-ribose 5-phosphate + ATP = D-ribose 1,5-diphosphate + ADP + 2 H(+). UBERON:0009583 spinal cord mantle layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009583 spinal cord lateral wall mantle layer|mantle layer lateral wall spinal cord GO:0050192 phosphoglycerate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050192 KEGG_REACTION:R01748|EC:3.1.3.20|RHEA:21156|MetaCyc:PHOSPHOGLYCERATE-PHOSPHATASE-RXN glycerophosphate phosphatase activity|D-glycerate-2-phosphate phosphohydrolase activity|D-2-phosphoglycerate phosphatase activity Catalysis of the reaction: 2-phospho-D-glycerate + H(2)O = D-glycerate + phosphate. UBERON:0009584 1st arch mandibular mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009584 mandibular component mesenchyme|mesenchyme of mandibular component|mesenchymal region of mandibular component of first pharyngeal arch|mandibular mesenchyme Mesenchyme that is part of a 1st arch mandibular component. GO:0050193 phosphoketolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050193 RHEA:10468|EC:4.1.2.9|MetaCyc:PHOSPHOKETOLASE-RXN D-xylulose-5-phosphate D-glyceraldehyde-3-phosphate-lyase (phosphate-acetylating) activity|D-xylulose-5-phosphate D-glyceraldehyde-3-phosphate-lyase (adding phosphate; acetyl-phosphate-forming)|xylulose-5-phosphate phosphoketolase activity Catalysis of the reaction: D-xylulose 5-phosphate + phosphate = acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O. GO:0050198 pinosylvin synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050198 MetaCyc:PINOSYLVIN-SYNTHASE-RXN|KEGG_REACTION:R02505|RHEA:12552|EC:2.3.1.146 stilbene synthase activity|malonyl-CoA:cinnamoyl-CoA malonyltransferase (cyclizing)|pine stilbene synthase activity Catalysis of the reaction: trans-cinnamoyl-CoA + 3 H(+) + 3 malonyl-CoA = 4 CO(2) + 4 CoA + pinosylvin. GO:0050199 piperidine N-piperoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050199 EC:2.3.1.145|MetaCyc:PIPERIDINE-N-PIPEROYLTRANSFERASE-RXN|KEGG_REACTION:R03994|RHEA:14561 piperoyl-CoA:piperidine N-piperoyltransferase activity|(E,E)-piperoyl-CoA:piperidine N-piperoyltransferase activity|piperidine piperoyltransferase activity Catalysis of the reaction: (E,E)-piperoyl-CoA + piperidine = N-[(E,E)-piperoyl]piperidine + CoA + H(+). GO:0050196 [phosphorylase] phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050196 EC:3.1.3.17|MetaCyc:PHOSPHORYLASE-PHOSPHATASE-RXN glycogen phosphorylase phosphatase activity|phosphorylase phosphatase activity|phosphorylase a phosphohydrolase activity|phosphorylase a phosphatase activity|type 1 protein phosphatase activity|protein phosphatase C|PR-enzyme Catalysis of the reaction: [phosphorylase a] + 4 H2O = 2 [phosphorylase b] + 4 phosphate. GO:0050197 phytanate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050197 MetaCyc:PHYTANATE--COA-LIGASE-RXN|EC:6.2.1.24|Reactome:R-HSA-389622|KEGG_REACTION:R03631|RHEA:21380 phytanate:CoA ligase (AMP-forming)|phytanoyl-CoA ligase activity Catalysis of the reaction: ATP + CoA + phytanate = AMP + diphosphate + H(+) + phytanoyl-CoA. UBERON:0009570 spinal cord sulcus limitans biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009570 spinal cord lateral wall sulcus limitans A sulcus limitans of neural tube that is part of a future spinal cord. CHEBI:17769 4-aminobutanal biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17769 CHEBI:17767 D-mannonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17767 CHEBI:17768 N-acetylputrescine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17768 CHEBI:17766 cyclohexane-1,3-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17766 CHEBI:17763 4-methylumbelliferyl acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17763 UBERON:0009571 ventral midline biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009571 In protostomes (such as insects, snails and worms) as well as deuterostomes (vertebrates), the midline is an embryonic region that functions in patterning of the adjacent nervous tissue. The ventral midline in insects is a cell population extending along the ventral surface of the embryo and is the region from which cells detach to form the ventrally located nerve cords. In vertebrates, the midline is originally located dorsally. During development, it folds inwards and becomes the ventral part of the dorsally located neural tube and is then called the ventral midline, or floor plate. UBERON:0009572 lumen of central canal of spinal cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009572 spinal cord lumen|central canal lumen|cavity of central canal of spinal cord|neural lumen A cerebrospinal fluid-filled space that runs longitudinally through the length of the entire spinal cord. The central canal is contiguous with the ventricular system of the brain. The central canal represents the adult remainder of the neural tube. CHEBI:17764 2-C-methyl-D-erythritol 4-(dihydrogen phosphate) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17764 CHEBI:17761 ceramide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17761 CHEBI:17762 5alpha-cholestan-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17762 UBERON:0009576 medulla oblongata sulcus limitans biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009576 A sulcus limitans of neural tube that is part of a future medulla oblongata. CHEBI:17760 methyl sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17760 UBERON:0009577 metencephalon sulcus limitans biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009577 A sulcus limitans of neural tube that is part of a future metencephalon. UBERON:0009578 myelencephalon sulcus limitans biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009578 A sulcus limitans of neural tube that is part of a future myelencephalon. UBERON:0009568 trunk region of vertebral column biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009568 trunk skeleton|trunk vertebral column|trunk spine|thoracolumbar column|thoracolumbar vertebrae set|thoracolumbar region|presacral region|thoracolumbar vertebral column|thoracolumbar region of vertebral column|trunk region|trunk vertebrae series Subdivision of vertebral column that corresponds to the trunk of the body, containing the trunk/presacral vertebrae. In organisms that have a thoracic and lumbar distinction, this corresponds to the sum of both of these regions. UBERON:0010546 metapodial skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010546 metapodium|metapodial skeleton|skeleton of metapodium|metapodium skeleton|metacarpal/metatarsal skeleton|skeletal parts of metapodium Subdivision of skeleton that corresponds to metapodium region, between acropodial skeleton and mesopdoial skeleton. UBERON:0009569 subdivision of trunk biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009569 trunk subdivision|region of trunk UBERON:0010544 metacarpus skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010544 ossa metacarpi [I-V]|fore metapodium|metacarpalia|set of metacarpals|metacarpal bones|ossa metacarpalia [I-V]|skeleton of metacarpus|anterior metapodial skeleton|fore metapodial skeleton|metacarpals [I-V]|metacarpals set|set of metacarpal bones|anterior metapodium|set of metacarpals [I-V]|metacarpal skeleton The metacarpus is the intermediate part of the manus skeleton that is located between the phalanges (bones of the fingers) distally and the carpus which forms the connection to the forearm. The metacarpus consists of metacarpal bones. The metacarpals form a transverse arch to which the rigid row of distal carpal bones are fixed. The peripheral metacarpals (those of the thumb and little finger) form the sides of the cup of the palmar gutter and as they are brought together they deepen this concavity. The index metacarpal is the most firmly fixed, while the thumb metacarpal articulates with the trapezium and acts independently from the others. The middle metacarpals are tightly united to the carpus by intrinsic interlocking bone elements at their bases. The ring metacarpal forms a transitional element of the semi-independent last metacarpal. [WP,unvetted]. UBERON:0010545 metatarsus skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0010545 ossa metatarsalia|ossa metatarsi[I-V]|posterior metapodium|metatarsals [I-V]|posterior metapodial skeleton|set of metatarsal bones|metatarsalia|set of metatarsals [I-V]|metatarsal bones set|metatarsal skeleton|ossa metatarsalia [I-V]|skeleton of metatarsus Limb segment that consists of the long bones of the pes. The metatarsals are analogous to the metacarpal bones of the manus. CHEBI:17759 cholesta-5,7-dien-3beta-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17759 CHEBI:17756 (S)-mandelate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17756 CHEBI:17757 plastoquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17757 CHEBI:17754 glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17754 CHEBI:17755 cystathionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17755 CHEBI:17752 N(6)-acetyl-L-lysine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17752 CHEBI:17750 glycine betaine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17750 CHEBI:17751 dihydrostreptomycin 3'alpha,6-bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17751 UBERON:0009564 distal limb integumentary appendage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009564 keratin sheath|unguis|keratin plate|hoof, claw or nail|hoof or claw A nail, hoof or claw. UBERON:0009565 nail of manual digit biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009565 finger nail|forelimb digit claw|nail of finger|manual claw|fingernail|claw of hand|nail plate of finger|claw of manus A nail that is part of a manual digit. UBERON:0009566 intestinal submucosa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009566 submucosa of intestine A submucosa that is part of a intestine. UBERON:0009567 nail of pedal digit biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009567 nail plate of toe|hindlimb digit claw|toe nail|nail of toe|pedal claw|claw of toe|toenail|nail of pes|claw of pes|claw of foot|hindlimb claw A nail that is part of a pedal digit. GO:0001136 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001136 GO:0001137 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001137 GO:0001138 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001138 GO:0001139 RNA polymerase II complex recruiting activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001139 transcription factor activity, core RNA polymerase II recruiting|core RNA polymerase II recruiting transcription factor activity Interacting selectively and non-covalently with an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way in order to facilitate the aggregation, arrangement and bonding together of proteins on an RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase. GO:0001132 obsolete RNA polymerase II transcription factor activity, TBP-class protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001132 TRF protein binding RNA polymerase II transcription factor activity|TBP-class protein binding RNA polymerase II transcription factor activity|TATA-binding protein binding RNA polymerase II transcription factor activity OBSOLETE. Interacting selectively and non-covalently with a member of the class of TATA-binding proteins (TBP), including any of the TBP-related factors (TRFs), in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well. GO:0001133 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001133 GO:0001134 obsolete transcription regulator recruiting activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001134 transcription factor recruiting activity|transcription factor activity, transcription factor recruiting|transcription factor recruiting transcription factor activity OBSOLETE. The function of binding to an RNA polymerase (RNAP) transcription regulator and recruiting it to the general transcription machinery complex in order to modulate transcription initiation. GO:0001135 obsolete RNA polymerase II transcription regulator recruiting activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001135 RNA polymerase II transcription factor recruiting activity|transcription factor activity, TFIIH-class transcription factor recruiting|transcription factor activity, TFIIF-class transcription factor recruiting|transcription factor activity, TFIIE-class transcription factor recruiting|TFIIH-class transcription factor recruiting transcription factor activity|TFIIF-class transcription factor recruiting transcription factor activity|transcription factor activity, RNA polymerase II transcription factor recruiting|TFIIE-class transcription factor recruiting transcription factor activity|RNA polymerase II transcription factor recruiting transcription factor activity OBSOLETE. The function of binding to an RNA polymerase II (RNAP II) transcription regulator and recruiting it to the general transcription machinery complex in order to modulate transcription initiation. GO:0001130 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001130 GO:0001131 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001131 GO:0015777 teichoic acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015777 The directed movement of teichoic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Teichoic acid is any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues. CHEBI:27081 transition element atom biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27081 CHEBI:27082 trehalose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27082 GO:0015778 hexuronide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015778 The directed movement of hexuronide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Hexuronides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of a hexuronate. GO:0015779 glucuronoside transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015779 glucuronide transport The directed movement of glucuronosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucuronosides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of glucuronate. CHEBI:27083 trehalose mycolate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27083 CHEBI:27084 trehalose phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27084 GO:0015773 raffinose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015773 The directed movement of raffinose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Raffinose occurs in plants almost as commonly as sucrose and is present in cereal grains, cotton seeds, and many legumes. It is synthesized from sucrose by transfer of a galactopyranoside from myo-inositol. GO:0015774 polysaccharide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015774 The directed movement of polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. GO:0015775 beta-glucan transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015775 The directed movement of beta-glucans into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Beta-glucans are compounds composed of glucose residues linked by beta-glucosidic bonds. GO:0015776 capsular polysaccharide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015776 capsular-polysaccharide transport|capsule polysaccharide transport The directed movement of capsular polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Capsular polysaccharides make up the capsule, a protective structure surrounding some species of bacteria and fungi. CHEBI:76001 (R)-laudanine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76001 CHEBI:52035 sulfooxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52035 GO:0015770 sucrose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015770 The directed movement of sucrose into, out of or within a cell, or between cells by means of some agent such as a transporter or pore. Sucrose is the disaccharide fructofuranosyl-glucopyranoside. GO:0015771 trehalose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015771 The directed movement of trehalose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Trehalose is a disaccharide isomeric with sucrose and obtained from certain lichens and fungi. GO:0015772 oligosaccharide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015772 The directed movement of oligosaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligosaccharides are molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages. CHEBI:52030 murideoxycholic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52030 CHEBI:52031 glycochenodeoxycholic acid 7-sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52031 GO:0001147 transcription termination site sequence-specific DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001147 bacterial-type RNA polymerase termination site sequence-specific DNA binding|mitochondrial RNA polymerase termination site sequence-specific DNA binding|transcription termination site DNA binding|mitochondrial RNA polymerase terminator site sequence-specific DNA binding transcription factor activity|transcription factor activity, mitochondrial RNA polymerase terminator site sequence-specific binding Interacting selectively and non-covalently with a sequence of DNA that promotes termination by RNA polymerase. The transcribed region might be described as a gene, cistron, or operon. GO:0001148 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001148 GO:0001149 obsolete transcription factor activity, bacterial-type RNA polymerase termination site sequence-specific binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001149 bacterial-type RNA polymerase termination site sequence-specific DNA binding transcription factor activity OBSOLETE. Interacting selectively and non-covalently with a sequence of DNA that is a termination site for bacterial-type RNA polymerase in order to promote transcription termination by bacterial-type RNA polymerase. GO:0001143 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001143 GO:0001144 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001144 CHEBI:52028 8-methoxyfurocoumarin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52028 GO:0001145 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001145 GO:0001146 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001146 GO:0001140 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001140 GO:0001141 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001141 GO:0001142 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001142 CHEBI:27086 tributylstannane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27086 CHEBI:27092 tricarboxylic acid trianion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27092 GO:0015788 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015788 GO:0015789 UDP-N-acetylgalactosamine transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015789 UDP-N-acetylgalactosamine transport The directed movement of UDP-N-acetylgalactosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-N-acetylgalactosamine is a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate. CHEBI:27093 tricarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27093 GO:0015784 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015784 GO:0015785 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015785 GO:0015786 UDP-glucose transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015786 The process in which UDP-glucose is transported across a membrane. GO:0015787 UDP-glucuronic acid transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015787 UDP-glucuronic acid transport The directed movement of UDP-glucuronic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-glucuronic acid is a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate. GO:0015780 nucleotide-sugar transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015780 nucleotide-sugar transport The directed movement of nucleotide-sugars into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Nucleotide-sugars are any nucleotide in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative. CHEBI:52023 hyodeoxycholic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52023 GO:0015781 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015781 GO:0015782 CMP-N-acetylneuraminate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015782 CMP-N-acetylneuraminate transport|CMP-sialic acid transport The directed movement of CMP-N-acetylneuraminate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:52025 8-hydroxyfurocoumarin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52025 GO:0015783 GDP-fucose transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015783 GDP-fucose transport The directed movement of GDP-fucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate. CHEBI:52026 amorpha-4,11-diene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52026 CHEBI:52020 6-decylubiquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52020 CHEBI:52021 6-decylubiquinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52021 CHEBI:52022 taurohyocholic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52022 GO:0001114 protein-DNA-RNA complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0001114 A macromolecular complex containing protein, DNA, and RNA molecules. GO:0001115 protein-DNA-RNA complex subunit organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001115 protein-DNA-RNA complex subunit organisation Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-DNA-RNA complex. GO:0001116 protein-DNA-RNA complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001116 The aggregation, arrangement and bonding together of proteins, DNA, and RNA molecules to form a protein-DNA-RNA complex. GO:0001117 protein-DNA-RNA complex disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001117 The disaggregation of a protein-DNA-RNA complex into its constituent components. GO:0001110 promoter clearance from RNA polymerase III promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001110 Any process involved in the transition from the initiation to the elongation phases of transcription by RNA polymerase III, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase. GO:0001111 promoter clearance from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001111 promoter escape from RNA polymerase II promoter Any process involved in the transition from the initiation to the elongation phases of transcription by RNA polymerase II, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors. GO:0001112 DNA-templated transcription open complex formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001112 promoter melting|DNA-templated transcriptional open complex formation|DNA-dependent transcriptional open complex formation Any process involved in the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble. GO:0001113 transcription open complex formation at RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001113 transcriptional open complex formation at RNA polymerase II promoter|RNA polymerase II promoter melting Any process involved in the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase II preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble. CHEBI:134408 N-acetylcadaverine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134408 CHEBI:134409 N(alpha)-acetyl-L-methionyl-L-asparagine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134409 CHEBI:134406 prostaglandin G3 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134406 CHEBI:134407 prostaglandin H3 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134407 GO:0015759 beta-glucoside transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015759 The directed movement of beta-glucosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Beta-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in a beta configuration. GO:0039722 suppression by virus of host toll-like receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039722 suppression by virus of host TLR signaling pathway|inhibition of host TLR pathway by virus Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of toll-like receptor (TLR) signaling in the host organism. GO:0015755 fructose transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015755 fructose transport The directed movement of fructose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey. CHEBI:134400 cationic peptidyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134400 GO:0039723 suppression by virus of host TBK1 activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039723 inhibition of host TBK1 by virus Any process in which a virus stops, prevents, or reduces the activity of the host serine/threonine kinase TBK1. GO:0015756 fucose transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015756 fucose transport The process in which fucose is transported across a lipid bilayer, from one side of a membrane to the other. Fucose is 6-deoxygalactose and has two enantiomers, D-fucose and L-fucose. GO:0039720 virogenic stroma biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0039720 VS A nuclear viral factory formed by Baculoviruses. A vesicular structure in which virions are assembled. GO:0015757 galactose transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015757 galactose transport The process in which galactose is transported across a lipid bilayer, from one side of a membrane to the other. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose. GO:0039721 peristromal region viral factory biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0039721 PR A nuclear viral factory formed at the periphery of the host cell nucleus by Baculoviruses. GO:0015758 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015758 GO:0015751 arabinose transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015751 arabinose transport The process in which arabinose, a pentose monosaccharide that occurs in both D and L configurations, is transported across a lipid bilayer, from one side of a membrane to the other. GO:0015752 D-ribose transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015752 D-ribose transport The process in which D-ribose is transported across a lipid bilayer, from one side of a membrane to the other. As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12. CHEBI:134405 S-anthraniloyl-L-cysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134405 GO:0039724 suppression by virus of host IKBKE activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039724 inhibition of host IKBKE by virus Any process in which a virus stops, prevents, or reduces the activity of the host I-kappa-B kinase epsilon (IKBKE/IKK-epsilon/IKK-E). GO:0015753 D-xylose transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015753 D-xylose transport The process in which D-xylose is transported across a lipid bilayer, from one side of a membrane to the other. D-xylose (the naturally occurring enantiomer is always D-) is a constituent of plant polysaccharides. GO:0015754 allose transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015754 allose transport The process in which allose is transported across a lipid bilayer, from one side of a membrane to the other. Allose is an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3. CHEBI:76024 dotriacontanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76024 GO:0015750 pentose transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015750 pentose transport The process in which pentose is transported across a lipid bilayer, from one side of a membrane to the other. A pentose is any aldose with a chain of five carbon atoms in the molecule. GO:0001118 transcription ternary complex disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001118 transcription protein-DNA-RNA complex disassembly The disaggregation of a transcription ternary complex, composed of RNA polymerase, template DNA, and an RNA transcript, into its constituent components. GO:0001119 protein-DNA-RNA complex remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001119 The acquisition, loss, or modification of macromolecules within a protein-DNA-RNA complex, resulting in the alteration of an existing complex. GO:0001125 transcription termination from bacterial-type RNA polymerase promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001125 The process in which the synthesis of an RNA molecule by a bacterial-type RNA polymerase using a DNA template is completed. GO:0001126 bacterial-type RNA polymerase preinitiation complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001126 bacterial-type RNA polymerase transcription PIC biosynthesis|bacterial-type RNA polymerase transcription PIC formation|bacterial-type RNA polymerase transcriptional preinitiation complex formation The aggregation, arrangement and bonding together of proteins on a bacterial-type RNA polymerase promoter DNA to form the transcriptional preinitiation complex (PIC), required for transcription. GO:0001127 transcription open complex formation at bacterial-type RNA polymerase promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001127 transcriptional open complex formation at bacterial-type RNA polymerase promoter Any process involved in the melting of the DNA hybrid of the core promoter region within a bacterial-type RNA polymerase promoter to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble. GO:0001128 obsolete RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001128 RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly OBSOLETE. Interacting selectively and non-covalently with an RNA polymerase II (RNAP II) regulatory transcription factor and also with the RNAP II basal transcription machinery in order to increase the frequency, rate or stability of the aggregation, arrangement and bonding together of proteins on RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC). Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between activating transcription factors and the basal RNAP II transcription machinery. GO:0001121 bacterial transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001121 transcription from bacterial-type RNA polymerase promoter The synthesis of RNA from a DNA template by a bacterial-type RNA polymerase, originating at a bacterial-type promoter. GO:0001122 promoter clearance from bacterial-type RNA polymerase promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001122 Any process involved in the transition from the initiation to the elongation phase of transcription by a bacterial-type RNA polymerase, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance generally involves dissociation of the sigma initiation factor. GO:0001123 transcription initiation from bacterial-type RNA polymerase promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001123 Any process involved in the assembly of bacterial-type RNA polymerase preinitiation complex (PIC) at the core promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. The initiation phase ends just before and does not include promoter clearance, or release, which is the transition between the initiation and elongation phases of transcription. GO:0001124 transcription elongation from bacterial-type RNA polymerase promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001124 RNA elongation from bacterial-type RNA polymerase promoter The extension of an RNA molecule after transcription initiation and promoter clearance at a bacterial-type RNA polymerase promoter by the addition of ribonucleotides catalyzed by a bacterial-type RNA polymerase. GO:0039719 tube viral factory biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0039719 A cytoplasmic viral factory derived from the Golgi in which Bunyaviridae replication takes place. Tubes are membranous structures close to the assembly and budding sites, and their function may be to connect viral replication and morphogenesis inside viral factories. CHEBI:134417 10,11-dihydro-12-oxoleukotriene B4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134417 GO:0039717 spherule viral factory biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0039717 Wikipedia:Viroplasm A cytoplasmic viral factory which is a 50-400nm diameter membrane invagination. Spherules can appear on several enveloped cellular components depending on the virus. GO:0039718 double membrane vesicle viral factory biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0039718 DMV viral factory A cytoplasmic viral factory that consists of a double-membrane bound vesicle. Has a diameter of 200-300nm and is derived from the endoplasmic reticulum or Golgi apparatus. Produced by Picornaviridae, Nidovirales, Arteriviridae and Coronaviridae. GO:0001120 protein-DNA complex remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001120 The acquisition, loss, or modification of macromolecules within a protein-DNA complex, resulting in the alteration of an existing complex. CL:0010021 cardiac myoblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0010021 CL:0010022 cardiac neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0010022 CHEBI:27066 (9R,10R)-9,10-dihydrophenanthrene-9,10-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27066 CL:0010020 cardiac glial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0010020 GO:0015766 disaccharide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015766 The directed movement of disaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Disaccharides are sugars composed of two monosaccharide units. GO:0039711 cytoplasmic helical capsid assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039711 The assembly of a helical viral capsid in the cytoplasm. Occurs by assembling around the viral genome. GO:0015767 lactose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015767 The directed movement of lactose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lactose is a disaccharide 4-O-beta-D-galactopyranosyl-D-glucose, and constitutes roughly 5% of the milk in almost all mammals. GO:0039712 induction by virus of host catalytic activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039712 induction by virus of host enzyme activity Any viral process that activates or increases the frequency, rate or extent of host catalytic activity. CHEBI:134412 10-formyltetrahydrofolyl-(Glu)n biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134412 GO:0015768 maltose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015768 The directed movement of maltose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the catabolism of glycogen and starch. GO:0015769 melibiose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015769 The directed movement of melibiose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Melibiose is the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose. GO:0039710 cytoplasmic icosahedral capsid assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039710 The assembly of an icosahedral viral capsid in the cytoplasm. Often occurs by assembling around the viral genome. GO:0039715 nuclear viral factory biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0039715 A viral factory located in the nucleus of a host cell. GO:0015762 rhamnose transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015762 rhamnose transport The process in which rhamnose is transported across a lipid bilayer, from one side of a membrane to the other. Rhamnose occurs commonly as a compound of plant glycosides, in polysaccharides of gums and mucilages, and in bacterial polysaccharides. It is also a component of some plant cell wall polysaccharides and frequently acts as the sugar components of flavonoids. GO:0039716 viroplasm viral factory biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0039716 Wikipedia:Viroplasm A cytoplasmic viral factory that is electron dense due to high levels of viral RNA. Produced by nucleo-cytoplasmic large DNA viruses (NCLDV) like Poxviridae, Asfarviridae and Iridoviridae, and dsRNA viruses like Reoviridae. CHEBI:134416 3-oxo fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134416 GO:0015763 N-acetylgalactosamine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015763 The directed movement of N-acetylgalactosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. N-acetylgalactosamine, 2-acetamido-2-deoxygalactopyranose, is the n-acetyl derivative of galactosamine. CHEBI:134413 10-formyltetrahydrofolyl-(Glu)n polyanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134413 GO:0039713 viral factory biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0039713 VZ:1951 virus factory An intracellular compartment in a host cell which increases the efficiency of viral replication, and shields the virus from host defenses. Viral factories can be either cytoplasmic or nuclear and often arise from extensive rearrangement of host cell cytoskeletal and/or cell membrane compartments. GO:0015764 N-acetylglucosamine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015764 The directed movement of N-acetylglucosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015765 methylgalactoside transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015765 The directed movement of methylgalactoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Methylgalactoside is a compound in which the H of the OH group on carbon-1 of galactose is replaced by a methyl group. CHEBI:134414 2-hydroxyhexacosanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134414 GO:0039714 cytoplasmic viral factory biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0039714 A viral factory located in the cytoplasm of a host cell. CHEBI:76032 7(1)-hydroxychlorophyll a biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76032 GO:0015760 glucose-6-phosphate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015760 The directed movement of glucose-6-phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucose-6-phosphate is a monophosphorylated derivative of glucose with the phosphate group attached to C-6. GO:0015761 mannose transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015761 mannose transport The process in which mannose is transported across a lipid bilayer, from one side of a membrane to the other. Mannose is the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins. GO:0001129 obsolete RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001129 TBP-class protein binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly|TATA-binding protein binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly OBSOLETE. Interacting selectively and non-covalently with a member of the class of TATA-binding proteins (TBP), including any of the TBP-related factors (TRFs), to facilitate the aggregation, arrangement and bonding together of proteins on RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase. CHEBI:76036 (R)-2-hydroxylignoceric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76036 GO:0050103 dextrin dextranase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050103 MetaCyc:DEXTRIN-DEXTRANASE-RXN|RHEA:14625|EC:2.4.1.2 dextran dextrinase activity|dextrin 6-glucosyltransferase activity|1,4-alpha-D-glucan:1,6-alpha-D-glucan 6-alpha-D-glucosyltransferase activity Catalysis of the reaction: 1,4-alpha-D-glucosyl(n) + 1,6-alpha-D-glucosyl(m) = 1,4-alpha-D-glucosyl(n-1) + 1,6-alpha-D-glucosyl(m+1). GO:1990277 parasexual conjugation with cellular fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990277 mating A conjugation process that results in the union of cellular and genetic information from compatible mating types, without the formation of zygotes. An example of this process is found in Candida albicans. GO:0050104 L-gulonate 3-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050104 EC:1.1.1.45|RHEA:12889|MetaCyc:L-GULONATE-3-DEHYDROGENASE-RXN|Reactome:R-HSA-5661290|KEGG_REACTION:R02640 L-3-aldonate dehydrogenase activity|L-beta-hydroxy-acid-NAD-oxidoreductase activity|L-3-aldonic dehydrogenase activity|L-gulonate:NAD+ 3-oxidoreductase activity|L-gulonic acid dehydrogenase activity|L-beta-hydroxyacid dehydrogenase activity|L-3-hydroxyacid dehydrogenase activity Catalysis of the reaction: L-gulonate + NAD(+) = 3-dehydro-L-gulonate + H(+) + NADH. GO:1990278 obsolete positive regulation of MBF transcription factor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990278 positive regulation of MBF transcription factor activity OBSOLETE. Any process that activates or increases the frequency, rate or extent of activity of the transcription factor MBF. GO:1990279 obsolete negative regulation of MBF transcription factor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990279 negative regulation of MBF transcription factor activity OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor MBF. GO:0050101 mimosinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050101 EC:3.5.1.61|MetaCyc:MIMOSINASE-RXN|RHEA:13373|KEGG_REACTION:R04350 mimosine amidohydrolase activity Catalysis of the reaction: L-mimosine + H(2)O = 3-hydroxy-4H-pyrid-4-one + L-serine. GO:0050102 cellodextrin phosphorylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050102 MetaCyc:CELLODEXTRIN-PHOSPHORYLASE-RXN|EC:2.4.1.49|RHEA:23024 beta-1,4-oligoglucan:orthophosphate glucosyltransferase activity|1,4-beta-D-oligo-D-glucan:phosphate alpha-D-glucosyltransferase activity Catalysis of the reaction: 1,4-beta-D-glucosyl(n) + phosphate = 1,4-beta-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate. GO:1990273 snRNA 5'-end processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990273 Any process involved in forming the mature 5' end of an snRNA molecule. GO:0050107 monoterpenol O-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050107 MetaCyc:MONOTERPENOL-O-ACETYLTRANSFERASE-RXN|EC:2.3.1.69 acetyl-CoA:monoterpenol O-acetyltransferase activity|menthol transacetylase activity Catalysis of the reaction: acetyl-CoA + a monoterpenol = CoA + a monoterpenol acetate ester. GO:1990274 mitotic actomyosin contractile ring disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990274 mitotic actomyosin ring disassembly|mitotic cytokinetic ring disassembly|mitotic CAR disassembly|mitotic contractile actomyosin ring disassembly|mitotic constriction ring disassembly Any disaggregation of an actomyosin contractile ring into its constituent components that is involved in a mitotic cell cycle. GO:0050108 monoterpenyl-diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050108 MetaCyc:MONOTERPENYL-PYROPHOSPHATASE-RXN|EC:3.1.7.3 monoterpenyl-diphosphate diphosphohydrolase activity|bornyl pyrophosphate hydrolase activity|monoterpenyl-pyrophosphatase activity|bornyl diphosphate hydrolase activity Catalysis of the reaction: monoterpenyl diphosphate + H2O = monoterpenol + diphosphate. GO:0050105 L-gulonolactone oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050105 MetaCyc:L-GULONOLACTONE-OXIDASE-RXN|RHEA:32363|EC:1.1.3.8 L-gulono-gamma-lactone:O2 oxidoreductase activity|L-gulono-1,4-lactone:oxygen 3-oxidoreductase activity|GLO activity|L-gulono-gamma-lactone:oxidoreductase activity|L-gulono-gamma-lactone oxidase activity Catalysis of the reaction: L-gulono-1,4-lactone + O2 = L-xylo-hex-3-ulonolactone + H2O2. GO:1990275 preribosome binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990275 Interacting selectively and non-covalently with any part of a preribosome. GO:1990276 RNA 5'-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990276 Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the 5'-gamma-phosphate in an RNA molecule. GO:0050106 monomethyl-sulfatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050106 EC:3.1.6.16|KEGG_REACTION:R01145|MetaCyc:MONOMETHYL-SULFATASE-RXN|RHEA:14221 monomethyl-sulfate sulfohydrolase activity|monomethyl-sulphatase activity Catalysis of the reaction: H(2)O + monomethyl sulfate = H(+) + methanol + sulfate. GO:0039708 nuclear capsid assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039708 VZ:1516 The assembly of a virus capsid that occurs in the nucleus. The assembly of large icosahedral shells for herpesviridae and adenoviridae requires structural proteins that act as chaperones for assembly. GO:0039709 cytoplasmic capsid assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039709 VZ:1950 The assembly of a virus capsid that occurs in the cytoplasm. GO:1990270 platelet-derived growth factor receptor-ligand complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990270 IntAct:EBI-9080360 PDGF-CC-receptor alpha-beta complex|PDGF-DD-receptor alpha-beta complex|PDGF-BB-receptor alpha-beta complex|receptor-ligand complex|PDGF-AA-receptor alpha complex|PDGF-CC-receptor alpha complex|PDGF-BB-receptor alpha complex|PDGF receptor-ligand complex|PDGF-AB-receptor alpha complex|PDGF complex|PDGF-AB-receptor beta complex|PDGF-DD-receptor beta complex|PDGF-CC-receptor beta complex|PDGF-BB-receptor beta complex A tetrameric protein complex consisting of two platelet-derived growth factor (PDGF) receptor subunits and two PDGF ligand subunits. Binding of the PDGF ligand dimer to the PDGF receptor in the plasma membrane induces receptor dimerisation and activation. PDGFs are involved in a wide variety of signalling processes and are found in all vertebrates. At least two different receptor chains (A and B) and four types of ligand chains (A, B, C, and D) are known forming a wide variety of combinations of receptor-ligand complexes. GO:0050109 morphine 6-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050109 MetaCyc:MORPHINE-6-DEHYDROGENASE-RXN|EC:1.1.1.218 morphine:NAD(P)+ 6-oxidoreductase activity|reductase, naloxone|naloxone reductase activity Catalysis of the reaction: morphine + NAD(P)+ = morphinone + NAD(P)H + H+. GO:0039706 co-receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0039706 Interacting selectively and non-covalently with a coreceptor. A coreceptor acts in cooperation with a primary receptor to transmit a signal within the cell. GO:1990271 obsolete anti-Mullerian hormone biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990271 anti-Mullerian hormone OBSOLETE. Combining with anti-Mullerian hormone to initiate a change in cell activity. CL:0010012 cerebral cortex neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0010012 A neuron that is part_of a cerebral cortex. GO:0039707 pore formation by virus in membrane of host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039707 viroporin|pore formation in membrane of host cell by virus The aggregation, arrangement and bonding together of a set of components by a virus to form a pore complex in a membrane of a host organism. GO:1990272 anti-Mullerian hormone receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990272 Combining with anti-Mullerian hormone to initiate a change in cell activity. GO:0015737 galacturonate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015737 galacturonate transport The process in which galacturonate is transported across a lipid bilayer, from one side of a membrane to the other. CL:0010010 cerebellar stellate cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0010010 GO:0015738 glucuronate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015738 glucuronate transport The process in which glucuronate is transported across a lipid bilayer, from one side of a membrane to the other. CL:0010011 cerebral cortex GABAergic interneuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0010011 A GABAergic interneuron whose soma is located in the cerebral cortex. GO:0015739 sialic acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015739 The directed movement of sialic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0039700 fusion of viral membrane with host outer nuclear membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039700 fusion of viral membrane with host outer nuclear membrane involved in nuclear egress|viral primary envelope fusion with host outer nuclear membrane Fusion of a viral primary envelope with the host outer nuclear membrane during nuclear egress. The transitory primary envelope is acquired by the virus as it buds at the inner nuclear membrane and gains access to the perinuclear space. This membrane is lost by fusing with the host outer nuclear membrane during nuclear exit. GO:0015733 shikimate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015733 shikimate transport The process in which shikimate is transported across a lipid bilayer, from one side of a membrane to the other. CL:0000680 muscle precursor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000680 A non-terminally differentiated cell that is capable of developing into a muscle cell. GO:0039701 microtubule-dependent intracellular transport of viral material towards cell periphery biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039701 VZ:1816 The directed movement of the viral genome or a viral particle towards the cell periphery using host microtubules. Mostly used by viruses that replicate their genome near or in the nucleus to allows newly assembled viral progeny to reach the plasma membrane. CL:0000681 radial glial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000681 forebrain radial glial cell A cell present in the developing CNS. Functions as both a precursor cell and as a scaffold to support neuronal migration. GO:0015734 taurine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015734 The directed movement of taurine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015735 uronic acid transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015735 uronic acid transport The process in which uronic acid is transported across a lipid bilayer, from one side of a membrane to the other. CL:0000683 ependymoglial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000683 ependymal astrocyte A cell that transports hormones from neurosecretory cells. This nerve cell is characterized by bipolar shape and endfeet that contact a basal lamina around blood vessels, and/or the pia mater or vitreous body of the eye and additionally contact the ventricular surface or sub-retinal space. GO:0015736 hexuronate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015736 hexuronate transport The process in which hexuronate is transported across a lipid bilayer, from one side of a membrane to the other. A hexuronate is any monocarboxylic acid derived from a hexose by oxidation of C-6. GO:0039704 viral translational shunt biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039704 VZ:608 ribosomal shunt initiation pathway A viral translation initiation mechanism where ribosomes are loaded onto viral mRNA at the 5'-cap structure and start scanning for a short distance before by-passing the large internal leader region and initiating at a downstream start site. UBERON:0009638 orbitosphenoid ossification center biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009638 orbitosphenoid center GO:0039705 viral translational readthrough biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039705 VZ:859 viral stop codon readthrough|viral RNA suppression of termination The continuation of translation of a viral mRNA beyond a stop codon by the use of a special tRNA that recognizes the UAG and UGA codons as modified amino acids, rather than as termination codons. CHEBI:76042 aromatic amino-acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76042 GO:0015730 propanoate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015730 propionate transport The directed movement of propionate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0039702 viral budding via host ESCRT complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039702 VZ:1536 host-assisted viral budding|viral budding through the ESCRT machinery Viral budding which uses a host ESCRT protein complex, or complexes, to mediate the budding process. CL:0000686 cerebrospinal fluid secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000686 A columnar/cuboidal epithelial cell that secretes cerebrospinal fluid. CHEBI:42677 (2R)-2-hydroxypropylammonium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_42677 GO:0015731 3-hydroxyphenyl propanoate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015731 3-hydroxyphenyl propionate transport The directed movement of 3-hydroxyphenyl propanoate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015732 prostaglandin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015732 The directed movement of prostaglandins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0039703 RNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0039703 The cellular metabolic process in which a cell duplicates one or more molecules of RNA. CL:0010017 zygote biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0010017 A zygote in a plant or an animal. CL:0009014 Peyer's patch lymphocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0009014 Peyer's patch resident lymphocyte|small intestine Peyer's patch lymphocyte A lymphocyte that is part of a Peyer's patch. These cells have a major role in driving the immune response to antigens sampled from the intestinal lumen, and in regulating the formation of follicle-associated epithelium and M cells in Peyer's patches by converting intestitial enterocytes into M cells. CL:0009015 Peyer's patch follicular dendritic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0009015 A follicular dendritic cell located in the Peyer's patch. These cells from a meshwork in which Peyer's patch B cells reside. CHEBI:76044 omega-hydroxytriacontanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76044 UBERON:0009630 root of thoracic nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009630 thoracic neural root|nerve root part of thoracic spinal cord|thoracic nerve root A spinal nerve root that is part of a thoracic nerve. GO:0050100 methylitaconate delta-isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050100 MetaCyc:METHYLITACONATE-DELTA-ISOMERASE-RXN|EC:5.3.3.6|RHEA:23480|KEGG_REACTION:R03070 methylitaconate D-isomerase activity|methylitaconate isomerase activity|methylitaconate delta2-delta3-isomerase activity Catalysis of the reaction: 2-methylene-3-methylsuccinate = dimethylmaleate. UBERON:0009632 root of cervical nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009632 cervical neural root|root of cervical spinal nerve|cervical spinal root|nerve root part of cervical spinal cord GO:0050114 myo-inosose-2 dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050114 EC:4.2.1.44|MetaCyc:MYO-INOSOSE-2-DEHYDRATASE-RXN|KEGG_REACTION:R02782|RHEA:14065 2,4,6/3,5-pentahydroxycyclohexanone hydro-lyase (3,5/4-trihydroxycyclohexa-1,2-dione-forming)|inosose 2,3-dehydratase activity|ketoinositol dehydratase activity|2,4,6/3,5-pentahydroxycyclohexanone hydro-lyase activity Catalysis of the reaction: 2,4,6/3,5-pentahydroxycyclohexanone = 3D-3,5/4-trihydroxycyclohexane-1,2-dione + H(2)O. GO:1990288 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990288 GO:0001103 RNA polymerase II repressing transcription factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001103 Interacting selectively and non-covalently with an RNA polymerase II transcription repressing factor, a protein involved in negative regulation of transcription. GO:0050115 myosin-light-chain-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050115 EC:3.1.3.53|Reactome:R-HSA-419232|MetaCyc:MYOSIN-LIGHT-CHAIN-PHOSPHATASE-RXN myosin-light-chain phosphatase activity|[Myosin light-chain]-phosphatase activity|myosin light chain kinase phosphatase activity|protein phosphatase 2A|myosin light-chain kinase phosphatase activity|myosin-light-chain-phosphate phosphohydrolase activity Catalysis of the reaction: myosin light-chain phosphate + H2O = myosin light chain + phosphate. GO:0001104 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001104 GO:1990289 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990289 GO:0001105 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001105 GO:0050112 inositol 2-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050112 KEGG_REACTION:R01183|EC:1.1.1.18|MetaCyc:MYO-INOSITOL-2-DEHYDROGENASE-RXN|RHEA:16949 myo-inositol 2-dehydrogenase activity|inositol:NAD 2-dehydrogenase activity Catalysis of the reaction: myo-inositol + NAD(+) = 2,4,6/3,5-pentahydroxycyclohexanone + H(+) + NADH. GO:0050113 inositol oxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050113 MetaCyc:MYO-INOSITOL-OXYGENASE-RXN|RHEA:23696|KEGG_REACTION:R01184|EC:1.13.99.1|Reactome:R-HSA-5678327 meso-inositol oxygenase activity|myo-inositol oxygenase activity|MOO activity|myo-inositol:oxygen oxidoreductase activity Catalysis of the reaction: myo-inositol + O(2) = D-glucuronate + H(2)O + H(+). GO:0001106 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001106 GO:0050118 N-acetyldiaminopimelate deacetylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050118 EC:3.5.1.47|KEGG_REACTION:R02733|MetaCyc:N-ACETYLDIAMINOPIMELATE-DEACETYLASE-RXN|RHEA:20405 6-N-acetyl-LL-2,6-diaminoheptanedioate amidohydrolase activity|N-acetyl-LL-diaminopimelate deacylase activity|N6-acetyl-LL-2,6-diaminoheptanedioate amidohydrolase activity|N-acetyl-L-diaminopimelic acid deacylase activity Catalysis of the reaction: N-acetyl-LL-2,6-diaminopimelate + H(2)O = LL-2,6-diaminopimelate + acetate. GO:1990284 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990284 GO:0001100 negative regulation of exit from mitosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001100 down regulation of exit from mitosis|downregulation of exit from mitosis|down-regulation of exit from mitosis|inhibition of exit from mitosis Any process involved in the inhibition of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity). GO:0050119 N-acetylglucosamine deacetylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050119 EC:3.5.1.33|KEGG_REACTION:R01200|RHEA:20593|Reactome:R-HSA-2022887|MetaCyc:N-ACETYLGLUCOSAMINE-DEACETYLASE-RXN N-acetyl-D-glucosaminyl N-deacetylase activity|N-acetyl-D-glucosamine amidohydrolase activity|acetylaminodeoxyglucose acetylhydrolase activity Catalysis of the reaction: N-acetyl-D-glucosamine + H(2)O = D-glucosamine + acetate. GO:1990285 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990285 GO:0050116 N,N-dimethylformamidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050116 EC:3.5.1.56|RHEA:19517|MetaCyc:NN-DIMETHYLFORMAMIDASE-RXN|KEGG_REACTION:R02509 dimethylformamidase activity|DMFase activity|N,N-dimethylformamide amidohydrolase activity Catalysis of the reaction: N,N-dimethylformamide + H(2)O = dimethylamine + formate. GO:0001101 response to acid chemical biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0001101 response to acid anion|response to acid|response to oxoanion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form. GO:1990286 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990286 GO:0001102 RNA polymerase II activating transcription factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001102 Interacting selectively and non-covalently with an RNA polymerase II transcription activating factor, a protein involved in positive regulation of transcription. GO:0050117 N-acetyl-beta-alanine deacetylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050117 EC:3.5.1.21|RHEA:23212|MetaCyc:N-ACETYL-BETA-ALANINE-DEACETYLASE-RXN|KEGG_REACTION:R00909 N-acetyl-beta-alanine amidohydrolase activity Catalysis of the reaction: N-acetyl-beta-alanine + H(2)O = beta-alanine + acetate. GO:1990287 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990287 CL:0010003 epithelial cell of alveolus of lung biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0010003 alveolus of lung epithelial cell An epithelial cell that is part_of a alveolus of lung. GO:1990280 RNA localization to chromatin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990280 RNA localisation to chromatin A process in which RNA is transported to and maintained in a part of a chromosome that is organized into chromatin. CL:0010004 mononuclear cell of bone marrow biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0010004 bone marrow mononuclear cell A mononuclear cell that is part_of a bone marrow. GO:1990281 efflux pump complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990281 efflux transmembrane transporter complex|efflux pump A protein complex that is capable of efflux transmembrane transporter activity. CL:0010001 stromal cell of bone marrow biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0010001 bone marrow stromal cell A stromal cell that is part_of a bone marrow. GO:1990282 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990282 GO:1990283 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990283 CHEBI:42660 GDP-beta-L-galactose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_42660 GO:0015748 organophosphate ester transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015748 The directed movement of organophosphate esters into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organophosphate esters are small organic molecules containing phosphate ester bonds. GO:0015749 monosaccharide transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015749 monosaccharide transport The process in which a monosaccharide is transported across a lipid bilayer, from one side of a membrane to the other. Monosaccharides are the simplest carbohydrates; they are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides. UBERON:0009623 spinal nerve root biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009623 root of spinal nerve|spinal root|spinal neural root The paired bundles of nerve fibers entering and leaving the spinal cord at each segment. The dorsal and ventral nerve roots join to form the mixed segmental spinal nerves. The dorsal roots are generally afferent, formed by the central projections of the spinal (dorsal root) ganglia sensory cells, and the ventral roots efferent, comprising the axons of spinal motor and autonomic preganglionic neurons. There are, however, some exceptions to this afferent/efferent rule. GO:0015744 succinate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015744 The directed movement of succinate, the dianion of ethane dicarboxylic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015745 tartrate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015745 tartrate transport The process in which tartrate is transported across a lipid bilayer, from one side of a membrane to the other. GO:0015746 citrate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015746 The directed movement of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CL:0010009 camera-type eye photoreceptor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0010009 camera type eye photoreceptor cell GO:0015747 urate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015747 uric acid transport|urate transmembrane transport The directed movement of urate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015740 C4-dicarboxylate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015740 The directed movement of a C4-dicarboxylate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A C4-dicarboxylate is the anion of a dicarboxylic acid that contains four carbon atoms. CL:0000695 Cajal-Retzius cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000695 One of a transient population of pioneering neurons in the cerebral cortex. These cells are slender bipolar cells of the developing marginal zone. One feature of these cells in mammals is that they express the Reelin gene. CL:0010007 His-Purkinje system cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0010007 CL:0000696 PP cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000696 type F enteroendocrine cell A cell that stores and secretes pancreatic polypeptide hormone. GO:0015741 fumarate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015741 The directed movement of fumarate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CL:0010008 cardiac endothelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0010008 CHEBI:17699 16-hydroxytabersonine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17699 GO:0015742 alpha-ketoglutarate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015742 mitochondrial alpha-ketoglutarate/malate transport|2-oxoglutarate transport The directed movement of alpha-ketoglutarate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CL:0010005 atrioventricular bundle cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0010005 AV bundle cell A specialized cardiomyocyte that transmit signals from the AV node to the cardiac Purkinje fibers. GO:0015743 malate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015743 mitochondrial alpha-ketoglutarate/malate transport The directed movement of malate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CL:0010006 cardiac blood vessel endothelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0010006 CHEBI:17697 N-acetylserotonin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17697 CHEBI:76056 dTDP-beta-L-4-epi-vancosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76056 CHEBI:17698 chloramphenicol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17698 CHEBI:76054 1-O-oleoyl-N-acetylsphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76054 CHEBI:17695 casbene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17695 CHEBI:17696 isocyanuric acid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17696 CHEBI:76055 1-palmityl-2-acetyl-3-oleoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76055 GO:0001107 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001107 GO:0050110 mucinaminylserine mucinaminidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050110 MetaCyc:3.2.1.110-RXN|KEGG_REACTION:R04527|EC:3.2.1.97 endo-beta-N-acetylgalactosaminidase|endo-beta-N-acetyl-D-galactosaminidase activity|D-galactosyl-3-(N-acetyl-beta-D-galactosaminyl)-L-serine mucinaminohydrolase activity Catalysis of the reaction: D-galactosyl-3-(N-acetyl-beta-D-galactosaminyl)-L-serine + H2O = D-galactosyl-3-N-acetyl-beta-D-galactosamine + L-serine. CHEBI:17693 4-methoxy-1-methyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17693 GO:0050111 mycocerosate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050111 RHEA:10588|KEGG_REACTION:R05189|EC:2.3.1.111|MetaCyc:MYCOCEROSATE-SYNTHASE-RXN mycocerosic acid synthase activity|acyl-CoA:methylmalonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing) Catalysis of the reaction: acyl-CoA + 7n H(+) + n methylmalonyl-CoA + 2n NADPH = n CO(2) + n CoA + n H(2)O + multi-methyl-branched acyl-CoA + 2n NADP(+). GO:0001108 bacterial-type RNA polymerase holo enzyme binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001108 basal bacterial-type RNA polymerase transcription machinery binding Interacting selectively and non-covalently with the basal transcription machinery which is composed of a bacterial-type RNA polymerase core enzyme and a sigma factor, the minimal set of factors required for formation of the preinitiation complex (PIC) by a bacterial-type RNA polymerase. CHEBI:17694 dihydrolipoamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_17694 GO:0001109 promoter clearance during DNA-templated transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001109 promoter escape|promoter clearance during DNA-dependent transcription Any process involved in the transition from the initiation to the elongation phases of transcription by a DNA-dependent RNA polymerase, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors. CHEBI:76058 chloroorienticin B biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76058 CHEBI:17691 N-feruloylglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17691 UBERON:0009621 tail somite biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009621 A somite that is part of a tail. CHEBI:17692 cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_17692 UBERON:0009622 pronephric proximal straight tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009622 proximal straight tubules A proximal straight tubule that is part of a pronephros. GO:1990299 Bub1-Bub3 complex localization to kinetochore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990299 A cellular protein complex localization that acts on a Bub1-Bub3 complex; as a result, the complex is transported to, or maintained in, a specific location at the kinetochore. GO:0050125 N-benzyloxycarbonylglycine hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050125 MetaCyc:N-BENZYLOXYCARBONYLGLYCINE-HYDROLASE-RXN|RHEA:20900|EC:3.5.1.58|KEGG_REACTION:R02551 nalpha-carbobenzoxyamino acid amidohydrolase activity|benzyloxycarbonylglycine hydrolase activity|N-benzyloxycarbonylglycine urethanehydrolase activity|nalpha-benzyloxycarbonyl amino acid urethane hydrolase I|nalpha-benzyloxycarbonyl amino acid urethane hydrolase activity Catalysis of the reaction: N-benzyloxycarbonylglycine + H(2)O + H(+) = benzyl alcohol + CO(2) + glycine. GO:0050126 N-carbamoylputrescine amidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050126 EC:3.5.1.53|KEGG_REACTION:R01152|RHEA:22284|MetaCyc:N-CARBAMOYLPUTRESCINE-AMIDASE-RXN NCP|N-carbamoylputrescine amidohydrolase activity|carbamoylputrescine hydrolase activity Catalysis of the reaction: N-carbamoylputrescine + H(2)O + 2 H(+) = CO(2) + NH(4)(+) + putrescine. GO:0050123 N-acylmannosamine 1-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050123 MetaCyc:N-ACYLMANNOSAMINE-1-DEHYDROGENASE-RXN|KEGG_REACTION:R02651|RHEA:11540|EC:1.1.1.233 N-acyl-D-mannosamine dehydrogenase activity|N-acyl-D-mannosamine:NAD+ 1-oxidoreductase activity|N-acylmannosamine dehydrogenase activity|N-acetyl-D-mannosamine dehydrogenase activity Catalysis of the reaction: N-acyl-D-mannosamine + NAD(+) = N-acyl-D-mannosaminolactone + H(+) + NADH. GO:0050124 N-acylneuraminate-9-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050124 Reactome:R-HSA-4084989|EC:3.1.3.29|MetaCyc:N-ACYLNEURAMINATE-9-PHOSPHATASE-RXN|RHEA:13057 acylneuraminate 9-phosphatase activity|N-acylneuraminic acid 9-phosphate phosphatase activity|N-acylneuraminic (sialic) acid 9-phosphatase activity|N-acylneuraminate-9-phosphate phosphohydrolase activity Catalysis of the reaction: N-acylneuraminate 9-phosphate + H2O = N-acylneuraminate + phosphate. GO:1990295 post-anaphase microtubule array biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990295 PAA|post-anaphase array A cytoskeletal part that consists of an array of microtubules and associated molecules that forms at the end of anaphase, and in which microtubules are nucleated from an equatorial microtubule organizing center. GO:0050129 N-formylglutamate deformylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050129 KEGG_REACTION:R00525|EC:3.5.1.68|RHEA:12476|MetaCyc:N-FORMYLGLUTAMATE-DEFORMYLASE-RXN beta-citryl-L-glutamate-hydrolyzing enzyme|beta-citryl-L-glutamate amidase activity|beta-citrylglutamate amidase activity|beta-citryl-L-glutamate hydrolase activity|N-formylglutamate hydrolase activity|N-formyl-L-glutamate amidohydrolase activity|formylglutamate deformylase activity|beta-citryl-L-glutamate amidohydrolase activity Catalysis of the reaction: N-formyl-L-glutamate + H(2)O = L-glutamate + formate. GO:1990296 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990296 GO:1990297 renal amino acid absorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990297 A renal system process in which amino acids are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures. GO:0050127 N-carbamoylsarcosine amidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050127 EC:3.5.1.59|RHEA:20057|KEGG_REACTION:R01563|MetaCyc:N-CARBAMOYLSARCOSINE-AMIDASE-RXN N-carbamoylsarcosine amidohydrolase activity|CSHase activity|carbamoylsarcosine amidase activity Catalysis of the reaction: N-carbamoylsarcosine + H(2)O + 2 H(+) = CO(2) + NH(4)(+) + sarcosine. GO:0050128 N-feruloylglycine deacylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050128 MetaCyc:N-FERULOYLGLYCINE-DEACYLASE-RXN|KEGG_REACTION:R03579|RHEA:10484|EC:3.5.1.71 N-feruloylglycine amidohydrolase activity|N-feruloylglycine hydrolase activity Catalysis of the reaction: N-feruloylglycine + H(2)O = ferulate + glycine. GO:1990298 bub1-bub3 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990298 Protein complex that associates with the kinetochores. GO:0015719 allantoate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015719 allantoin/allantoate transport The directed movement of allantoate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:1990291 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990291 CL:0000666 fenestrated cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000666 window cell GO:1990292 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990292 CL:0000667 collagen secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000667 An extracellular matrix secreting cell that secretes collagen. CHEBI:27013 tocopherol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27013 GO:1990293 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990293 CL:0000669 pericyte cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000669 pericyte of Rouget|pericyte|ARC|adventitial reticular cell|adventitial cell|cell of Rouget An elongated, contractile cell found wrapped about precapillary arterioles outside the basement membrane. Pericytes are present in capillaries where proper adventitia and muscle layer are missing (thus distingushing this cell type from adventitial cells). They are relatively undifferentiated and may become fibroblasts, macrophages, or smooth muscle cells. GO:1990294 peptidyl-threonine trans-autophosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990294 The phosphorylation of a peptidyl-threonine to form peptidyl-O-phospho-L-threonine on an identical protein. For example, phosphorylation by the other kinase within a homodimer. GO:0015715 nucleotide-sulfate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015715 nucleotide-sulphate transport The directed movement of nucleotide sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015716 organic phosphonate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015716 alkylphosphonate transport The directed movement of phosphonates into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A phosphonate is any salt, anion, or ester of phosphonic acid (HPO(OH)2). GO:0015717 triose phosphate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015717 aldotriose phosphate transport The directed movement of triose phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:1990290 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990290 GO:0015718 monocarboxylic acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015718 The directed movement of monocarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015711 organic anion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015711 The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage. GO:0015712 hexose phosphate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015712 The directed movement of hexose phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015713 phosphoglycerate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015713 phosphoglycerate transport The process in which phosphoglycerate is transported across a lipid bilayer, from one side of a membrane to the other. UBERON:0009614 hindbrain neural plate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009614 A neural plate that develops_from a presumptive hindbrain. UBERON:0009615 midbrain hindbrain boundary neural plate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009615 MHB neural plate|midbrain-hindbrain boundary neural plate CL:0000661 distal tip cell (sensu Nematoda) biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000661 GO:0015714 phosphoenolpyruvate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015714 The directed movement of phosphoenolpyruvate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UBERON:0009616 presumptive midbrain biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009616 presumptive mesencephalon|early midbrain|future midbrain|mesencephalon A presumptive structure that has the potential to develop into a midbrain. CHEBI:76063 1-O-palmityl-2-O-methyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76063 CHEBI:76064 1-palmityl-2-methyl-3-oleoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76064 CL:0000663 valve cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000663 UBERON:0009617 head paraxial mesoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009617 somitomere|cephalic paraxial mesoderm|cranial paraxial mesoderm|head paraxial mesenchyme|cephalic paraxial mesenchyme|somitomeric mesoderm|cranial paraxial mesenchyme Bilateral mesenchymal mesoderm parallel and immediately adjacent to the neural tube/notochord; it generates a subset of extra-ocular, and other head, muscles. CHEBI:76061 1-O-palmitylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76061 UBERON:0009618 trunk paraxial mesoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009618 trunk paraxial mesenchyme|trunk and cervical paraxial mesenchyme CHEBI:76062 1-O-palmityl-3-oleoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76062 GO:0015710 tellurite transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015710 The directed movement of tellurite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:76068 N,O-dioleoylethanolamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76068 CHEBI:76065 1-oleoyl-2-palmitoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76065 GO:0050121 N-acylglucosamine 2-epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050121 EC:5.1.3.8|Reactome:R-HSA-6803761|MetaCyc:N-ACYLGLUCOSAMINE-2-EPIMERASE-RXN|RHEA:19033 N-acetylglucosamine 2-epimerase activity|N-acyl-D-glucosamine 2-epimerase activity|acylglucosamine 2-epimerase activity|N-acetyl-D-glucosamine 2-epimerase activity|GlcNAc 2-epimerase activity Catalysis of the reaction: N-acyl-D-glucosamine = N-acyl-D-mannosamine. GO:0050122 N-acylhexosamine oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050122 MetaCyc:N-ACYLHEXOSAMINE-OXIDASE-RXN|EC:1.1.3.29|KEGG_REACTION:R01203|RHEA:13029 N-acyl-D-hexosamine oxidase activity|N-acyl-D-hexosamine:oxygen 1-oxidoreductase activity|N-acyl-beta-D-hexosamine:oxygen 1-oxidoreductase activity Catalysis of the reaction: N-acetyl-D-glucosamine + H(2)O + O(2) = N-acetyl-D-glucosaminate + H(2)O(2) + H(+). UBERON:0009610 forebrain neural plate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009610 A neural plate that develops_from a future forebrain. GO:0050120 N-acetylhexosamine 1-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050120 EC:1.1.1.240|MetaCyc:N-ACETYLHEXOSAMINE-1-DEHYDROGENASE-RXN|KEGG_REACTION:R01202|RHEA:23144 N-acetylhexosamine dehydrogenase activity|N-acetyl-D-hexosamine dehydrogenase activity|N-acetyl-D-hexosamine:NAD+ 1-oxidoreductase activity Catalysis of the reaction: N-acetyl-D-glucosamine + H(2)O + NAD(+) = N-acetyl-D-glucosaminate + 2 H(+) + NADH. UBERON:0009611 midbrain neural plate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009611 A neural plate that develops_from a presumptive midbrain. GO:0050136 NADH dehydrogenase (quinone) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050136 EC:1.6.5.11|RHEA:46160|MetaCyc:NADH-DEHYDROGENASE-QUINONE-RXN D-diaphorase activity|reduced nicotinamide adenine dinucleotide (quinone) dehydrogenase activity|NADH:(quinone-acceptor) oxidoreductase activity|NADH-quinone oxidoreductase activity|DPNH-menadione reductase activity Catalysis of the reaction: NADH + H+ + a quinone = NAD+ + a quinol. GO:0050137 NADPH peroxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050137 MetaCyc:NADPH-PEROXIDASE-RXN|RHEA:15173|EC:1.11.1.2|KEGG_REACTION:R00113 triphosphopyridine nucleotide peroxidase activity|NADP peroxidase activity|NADPH:hydrogen-peroxide oxidoreductase activity|TPNH peroxidase activity|nicotinamide adenine dinucleotide phosphate peroxidase activity|TPN peroxidase activity Catalysis of the reaction: H(2)O(2) + H(+) + NADPH = 2 H(2)O + NADP(+). GO:0050134 N6-methyl-lysine oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050134 RHEA:23200|EC:1.5.3.4|MetaCyc:N6-METHYL-LYSINE-OXIDASE-RXN|KEGG_REACTION:R00612 N(6)-methyllysine oxidase activity|N6-methyllysine oxidase activity|epsilon-N-methyllysine demethylase activity|N6-methyl-L-lysine:oxygen oxidoreductase (demethylating)|epsilon-alkyl-L-lysine:oxygen oxidoreductase activity|epsilon-alkyllysinase activity|6-N-methyl-L-lysine:oxygen oxidoreductase (demethylating) Catalysis of the reaction: N(6)-methyl-L-lysine + H(2)O + O(2) = L-lysine + formaldehyde + H(2)O(2). GO:0050135 NAD(P)+ nucleosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050135 EC:3.2.2.6|MetaCyc:NADP+-NUCLEOSIDASE-RXN NAD(P)(+) nucleosidase activity|nicotinamide adenine dinucleotide (phosphate) glycohydrolase activity|triphosphopyridine nucleotidase activity|NAD(P) nucleosidase activity|nicotinamide adenine dinucleotide (phosphate) nucleosidase activity|NAD(P)+ glycohydrolase activity|NAD(P)ase activity Catalysis of the reaction: NAD(P)+ + H2O = ADP-ribose(P) + nicotinamide. CHEBI:27027 micronutrient biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27027 GO:0050138 nicotinate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050138 RHEA:12236|EC:1.17.1.5|MetaCyc:RXN-7637|MetaCyc:NICOTINATE-DEHYDROGENASE-RXN|KEGG_REACTION:R01720 nicotinic acid hydroxylase activity|nicotinate hydroxylase activity|nicotinate:NADP+ 6-oxidoreductase (hydroxylating) Catalysis of the reaction: H(2)O + NADP(+) + nicotinate = 6-hydroxynicotinate + H(+) + NADPH. GO:0050139 nicotinate-N-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050139 RHEA:19437|EC:2.4.1.196|MetaCyc:NICOTINATE-GLUCOSYLTRANSFERASE-RXN|KEGG_REACTION:R01722 nicotinate glucosyltransferase activity|UDP-glucose:nicotinate N-glucosyltransferase activity|UDP-glucose:nicotinic acid-N-glucosyltransferase activity|uridine diphosphoglucose-nicotinate N-glucosyltransferase activity|UDPglucose:nicotinate N-glucosyltransferase activity Catalysis of the reaction: nicotinate + UDP-D-glucose = N-(beta-D-glucosyl)nicotinate + UDP. CL:0000677 gut absorptive cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000677 Cell of the intestinal epithelium with a brush border made up of many parallel packed microvilli; associated with absorption, particularly of macromolecules. CHEBI:27023 toluene-4-sulfonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_27023 CHEBI:27024 toluenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27024 CL:0000678 commissural neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000678 CL:0000679 glutamatergic neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000679 CHEBI:27026 toxin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27026 GO:0015726 L-idonate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015726 L-idonate transport The process in which L-idonate is transported across a lipid bilayer, from one side of a membrane to the other. L-idonate is an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose. GO:0015727 lactate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015727 The directed movement of lactate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices. GO:0015728 mevalonate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015728 The directed movement of mevalonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:27021 toluate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27021 GO:0015729 oxaloacetate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015729 The directed movement of oxaloacetate, the anion of oxobutanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0015722 canalicular bile acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015722 Enables the transfer of bile acid from one side of a hepatocyte plasma membrane into a bile canaliculus. Bile canaliculi are the thin tubes formed by hepatocyte membranes. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine. CHEBI:76070 O-oleoylanandamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76070 GO:0015723 bilirubin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015723 The directed movement of bilirubin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UBERON:0009602 left lung associated mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009602 left lung mesenchyme Mesenchyme that is part of a developing left lung. CL:0000670 primordial germ cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000670 gonocyte|primitive germ cell A primordial germ cell is a diploid germ cell precursors that transiently exist in the embryo before they enter into close association with the somatic cells of the gonad and become irreversibly committed as germ cells. CHEBI:76071 2-oleoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76071 CL:0000671 centripetally migrating follicle cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000671 GO:0015724 formate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015724 The directed movement of formate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UBERON:0009603 right lung associated mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0009603 right lung mesenchyme Mesenchyme that is part of a developing right lung. GO:0015725 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0015725 CHEBI:76074 1-O-stearoyl-N-acetylsphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76074 CHEBI:42646 flaviolin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_42646 GO:0015720 allantoin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015720 allantoin transmembrane transport|allantoin/allantoate transport The directed movement of allantoin, (2,5-dioxo-4-imidazolidinyl)urea, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CL:0000675 female gamete biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0000675 A mature sexual reproductive cell of the female germline. CHEBI:76072 nicotinic acid-adenine dinucleotide phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_76072 GO:0015721 bile acid and bile salt transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015721 bile acid transport|bile salt transport The directed movement of bile acid and bile salts into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:76073 1-oleoyl-2-stearoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76073 CHEBI:76078 2-palmitoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76078 CHEBI:76079 2-arachidonoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76079 CL:0009004 retinal cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0009004 Any cell in the retina, the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates. CHEBI:76076 2-stearoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76076 CHEBI:76077 1-O-palmitoyl-N-acetylsphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_76077 GO:0050132 N-methylalanine dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050132 KEGG_REACTION:R01584|MetaCyc:N-METHYLALANINE-DEHYDROGENASE-RXN|EC:1.4.1.17|RHEA:21768 N-methyl-L-alanine:NADP+ oxidoreductase (demethylating, deaminating) Catalysis of the reaction: N-methyl-L-alanine + H(2)O + NADP(+) = H(+) + methylammonium + NADPH + pyruvate. GO:0050133 N6-hydroxylysine O-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050133 RHEA:22388|KEGG_REACTION:R03168|EC:2.3.1.102|MetaCyc:N6-HYDROXYLYSINE-O-ACETYLTRANSFERASE-RXN N6-hydroxylysine acetylase activity|N6-hydroxylysine:acetyl CoA N6-transacetylase activity|N(6)-hydroxylysine acetylase activity|acetyl-CoA:N6-hydroxy-L-lysine 6-acetyltransferase activity|acetyl-CoA:6-N-hydroxy-L-lysine 6-acetyltransferase activity Catalysis of the reaction: N(6)-hydroxy-L-lysine + acetyl-CoA = N(6)-acetyl-N(6)-hydroxy-L-lysine + CoA. GO:0050130 N-methyl-2-oxoglutaramate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050130 MetaCyc:N-METHYL-2-OXOGLUTARAMATE-HYDROLASE-RXN|EC:3.5.1.36|RHEA:24108|KEGG_REACTION:R01587 5-hydroxy-N-methylpyroglutamate synthase activity|N-methyl-2-oxoglutaramate methylamidohydrolase activity Catalysis of the reaction: N-methyl-2-oxoglutaramate + H(2)O = 2-oxoglutarate + methylammonium. CL:0009001 compound eye retinal cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0009001 Any cell in the compound eye, a light sensing organ composed of ommatidia. GO:0050131 N-methyl-L-amino-acid oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0050131 RHEA:11472|MetaCyc:N-METHYL-L-AMINO-ACID-OXIDASE-RXN|EC:1.5.3.2 N-methylamino acid oxidase activity|N-methyl-L-amino-acid:oxygen oxidoreductase (demethylating) Catalysis of the reaction: an N-methyl-L-amino acid + H2O + O2 = an L-amino acid + formaldehyde + H2O2. GO:1990233 intramolecular phosphotransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990233 A protein complex capable of catalyzing the transfer of a phosphate group from one position to another within a single molecule. GO:1990234 transferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990234 A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). GO:1990235 diamine N-acetyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990235 SAT tetramer|SAT complex|spermidine acetyltransferase complex A protein complex which is capable of diamine N-acetyltransferase activity. GO:1990236 proteasome core complex import into nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990236 The directed movement of the proteasome core complex (AKA core particle (CP)) from the cytoplasm into the nucleus. GO:1990230 iron-sulfur cluster transfer complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990230 IscA complex|Fe-S cluster transfer complex|SufA dimer|SufA complex A protein complex capable of catalyzing the transfer of an iron-sulfur (Fe-S) cluster from one compound (donor) to another (acceptor). GO:1990231 STING complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990231 stimulator of interferon genes complex A protein dimer containing two STING monomers. It binds cyclic purine di-nucleotides. Activation of the sting complex by 2',5'-3'-5'-cyclic GMP-AMP activates nuclear transcription factor kB (NF-kB) and interferon regulatory factor 3 (IRF3) which then induce transcription of the genes encoding type I IFN and cytokines active in the innate immune response. GO:1990232 phosphomannomutase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990232 PMM-2 complex|PMM-1 complex|PMM-2 dimer|PMM-1 dimer A protein complex capable of phosphomannomutase activity. BFO:0000050 part of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BFO_0000050 BFO:0000050 a core relation that holds between a part and its whole BFO:0000055 realizes biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BFO_0000055 BFO:0000055 BFO:0000051 has part biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BFO_0000051 BFO:0000051 a core relation that holds between a whole and its part GO:1990237 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990237 GO:1990238 double-stranded DNA endodeoxyribonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990238 dsDNA-specific endodeoxyribonuclease activity Catalysis of the hydrolysis of ester linkages within a double-stranded deoxyribonucleic acid molecule by creating internal breaks. GO:1990239 steroid hormone binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990239 Interacting selectively and non-covalently with a steroid hormone. BFO:0000054 realized in biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BFO_0000054 BFO:0000054 GO:1990244 histone kinase activity (H2A-T120 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990244 histone threonine kinase activity (H2A-T120 specific) Catalysis of the transfer of a phosphate group to the threonine-120 residue of histone H2A. GO:1990245 histone H2A-T120 phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990245 histone H2AT120 phosphorylation|histone H2A phosphorylation at T120 The modification of histone H2A by the addition of a phosphate group to a threonine residue at position 120 of the histone. GO:1990246 uniplex complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990246 mitochondrial uniporter complex|mitochondrial uniporter holocomplex A calcium channel complex in the mitochondrial inner membrane capable of highly-selective calcium channel activity. Its components include the EF-hand-containing proteins mitochondrial calcium uptake 1 (MICU1) and MICU2, the pore-forming subunit mitochondrial calcium uniporter (MCU) and its paralog MCUb, and the MCU regulator EMRE. GO:1990247 N6-methyladenosine-containing RNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990247 Interacting selectively and non-covalently with an RNA molecule modified by N6-methyladenosine (m6A), a modification present at internal sites of mRNAs and some non-coding RNAs. GO:1990240 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1990240 GO:1990241 obsolete nucleotide binding complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990241 nucleotide binding complex OBSOLETE. A protein complex that interacts selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose. An example of this is STING in E. coli (Q86WV6). GO:1990242 obsolete innate immune response complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990242 innate immune response complex OBSOLETE. A protein complex involved in the innate immune response. GO:1990243 atf1-pcr1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990243 A heterodimeric transcription factor complex composed of the bZIP proteins atf1 and pcr1. The heterodimer binds m26 sites (homologous to CRE). BFO:0000040 material entity biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BFO_0000040 An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time. GO:1990248 regulation of transcription from RNA polymerase II promoter in response to DNA damage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990248 Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of DNA damage. GO:1990249 nucleotide-excision repair, DNA damage recognition complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990249 A protein complex that is capable of identifying lesions in DNA, such as pyrimidine-dimers, intrastrand cross-links, and bulky adducts. The wide range of substrate specificity suggests that the repair complex recognizes distortions in the DNA helix. It subsequently recruits a nucleotide-excision repair, preincision complex. GO:1990255 subsynaptic reticulum organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990255 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a subsynaptic reticulum. A subsynaptic reticulum is an elaborate tubulolamellar membrane system that underlies the postsynaptic cell membrane. GO:1990256 signal clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990256 ligand clustering Grouping of multiple copies of a signal at a cellular location. May promote receptor clustering and alter the signal transduction response. GO:1990257 piccolo-bassoon transport vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990257 PTV A cytoplasmic dense-core vesicle that transports a range of proteins including piccolo, bassoon, N-cadherin and syntaxin. The transported proteins may be associated with the external side of the vesicle, rather than being contained within the vesicle, therefore forming an aggregate of vesicle and proteins. Piccolo-bassoon transport vesicles (or PTVs) range in size from approximately 80 nm in diameter for dense core vesicles to 130 nm by 220 nm in area for aggregates. They are packaged via the trans-Golgi network before being transported through the axon. GO:1990258 histone glutamine methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990258 The modification of a histone by addition of a methyl group to an glutamine residue. GO:1990251 nuclear exosome focus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990251 Mmi1 nuclear focus|nuclear body An nuclear body involved in nuclear mRNA surveilllance. Contains at least Mmi1, or an ortholog of it, and the nuclear exosome. GO:0001198 negative regulation of mating-type specific transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001198 down regulation of RNA polymerase II transcription, mating-type specific|downregulation of RNA polymerase II transcription, mating-type specific|down-regulation of RNA polymerase II transcription, mating-type specific|inhibition of RNA polymerase II transcription, mating-type specific Any mating-type specific process that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter. GO:0001199 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001199 GO:1990252 Syp1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990252 Syp1 dimer A protein complex that contributes to the endocytic process and bud growth in yeast. It is involved in the precise timing of actin assembly during endocytosis. GO:1990253 cellular response to leucine starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990253 CHEBI:25017 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of leucine. GO:1990254 keratin filament binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990254 Interacting selectively and non-covalently with a keratin filament, an intermediate filament composed of acidic and basic keratins (types I and II), typically expressed in epithelial cells. GO:0001194 maintenance of transcriptional fidelity during DNA-templated transcription elongation from bacterial-type RNA polymerase promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001194 maintenance of transcriptional fidelity during DNA-dependent transcription elongation from bacterial-type RNA polymerase promoter Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation from a bacterial-type RNA polymerase promoter. GO:0001195 maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase III promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001195 maintenance of transcriptional fidelity during DNA-dependent transcription elongation from RNA polymerase III promoter Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation from a RNA polymerase III promoter. GO:0001196 regulation of mating-type specific transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001196 Any mating-type specific process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:0001197 positive regulation of mating-type specific transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001197 up-regulation of transcription from an RNA polymerase II promoter, mating-type specific|activation of transcription from an RNA polymerase II promoter, mating-type specific|up regulation of transcription from an RNA polymerase II promoter, mating-type specific|upregulation of transcription from an RNA polymerase II promoter, mating-type specific|stimulation of transcription from an RNA polymerase II promoter, mating-type specific Any mating-type specific process that activates or increases the rate of transcription from an RNA polymerase II promoter. GO:1990250 transcription-coupled nucleotide-excision repair, DNA damage recognition complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990250 A protein complex that is capable of identifying lesions in DNA on the actively transcribed strand of the DNA duplex as well as a small subset of lesions not recognized by the general nucleotide-excision repair pathway. The wide range of substrate specificity suggests that the repair complex recognizes distortions in the DNA helix. It subsequently recruits a nucleotide-excision repair, preincision complex. GO:0001190 obsolete transcriptional activator activity, RNA polymerase II transcription factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001190 RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcription factor binding transcription activator activity OBSOLETE. Interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to increase the frequency, rate or extent of transcription from an RNA polymerase II promoter. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. GO:0001191 obsolete transcriptional repressor activity, RNA polymerase II transcription factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001191 RNA polymerase II transcription repressor activity|RNA polymerase II transcription factor binding transcription repressor activity|RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription OBSOLETE. Interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. GO:0001192 maintenance of transcriptional fidelity during DNA-templated transcription elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001192 maintenance of transcriptional fidelity during DNA-dependent transcription elongation Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation on a DNA template. GO:0001193 maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001193 maintenance of transcriptional fidelity during DNA-dependent transcription elongation from RNA polymerase II promoter Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation from an RNA polymerase II promoter. CHEBI:52092 ethoxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52092 CHEBI:134489 N-acetyl-L-methionyl-L-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134489 CHEBI:52094 peroxy acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52094 CHEBI:134486 dimethylphosphatidylethanolamine 32:0 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134486 CHEBI:52090 methoxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52090 CHEBI:134481 N-acetyl-L-methionyl-L-phenylalanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134481 CHEBI:134484 N-acetyl-L-methionyl-L-tryptophan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134484 GO:1990259 histone-glutamine methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990259 Catalysis of the reaction: S-adenosyl-L-methionine + (histone)-glutamine = S-adenosyl-L-homocysteine + (histone)-N5-methyl-glutamine. CHEBI:134482 N-acetyl-L-methionyl-L-tyrosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134482 GO:1990266 neutrophil migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990266 The movement of a neutrophil within or between different tissues and organs of the body. GO:1990267 response to transition metal nanoparticle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990267 response to neutral metal atoms|response to colloidal metal Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transition metal nanoparticle. GO:1990268 response to gold nanoparticle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990268 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gold nanoparticle stimulus. GO:1990269 RNA polymerase II C-terminal domain phosphoserine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990269 RNA Pol II C-terminal domain phosphoserine binding|RNAP II C-terminal domain phosphoserine binding Interacting selectively and non-covalently with phosphorylated serine residues in the C-terminal domain of RNA polymerase II. GO:1990262 anti-Mullerian hormone signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990262 A series of molecular signals initiated by the binding of anti-Mullerian hormone to its receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:1990263 spore wall assembly MAPK cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990263 MAPK cascade involved in nutrient response signaling|MAPK cascade in response to starvation A MAPK cascade that occurs as a result of deprivation of nourishment. GO:1990264 peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990264 Any peptidyl-tyrosine dephosphorylation that is involved in inactivation of protein kinase activity. GO:1990265 platelet-derived growth factor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990265 IntAct:EBI-2881436|IntAct:EBI-2881443|IntAct:EBI-2881451 PDGF complex|PDGF-AB dimer|PDGF-DD dimer|PDGF-BB dimer|PDGF-CC dimer|PDGF-AA dimer A protein complex consisting of two chains of platelet-derived growth factor (PDGF) subunits. PDGF dimers bind to PDGF receptors in the plasma membrane and induce receptor dimerisation and activation. PDGFs are involved in a wide variety of signalling processes. PDGFs are found in all vertebrates where at least 2 different chains (A and B) exist. In human (and other mammals), four types of PDGF chains (A, B, C, and D) are known which form five different dimers (AA, AB, BB, CC and DD). GO:1990260 negative regulation of transcription from RNA polymerase II promoter by transcription factor localization involved in response to DNA damage checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990260 Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter using a mechanism that involves the localization of a transcription factor and initiated in response to the DNA damage checkpoint signaling. GO:1990261 pre-mRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990261 pre-mRNA decay|unspliced RNA decay The chemical reactions and pathways resulting in the breakdown of the unspliced pre-mRNA (pre-messenger RNA). CHEBI:134499 13,14-dihydro-15-oxoprostaglandin E1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134499 BFO:0000066 occurs in biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BFO_0000066 BFO:0000066 b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t CHEBI:134491 N-acetyl-L-methionyl-L-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134491 BFO:0000067 contains process biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BFO_0000067 BFO:0000067 [copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t CHEBI:134492 N-acetyl-L-methionyl-L-valine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134492 BFO:0000062 preceded_by biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BFO_0000062 BFO:0000062 is preceded by|takes place after The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. CHEBI:134495 N-acetyl-L-methionyl-L-threonine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134495 BFO:0000063 precedes biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BFO_0000063 BFO:0000063 x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. CHEBI:52086 glyceollin III biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52086 CHEBI:134493 phosphatidylethanolamine 40:1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134493 BFO:0000019 quality biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BFO_0000019 GO:0001176 transcriptional start site selection at bacterial-type RNA polymerase promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001176 Any process involved in the selection of the specific location within the template strand of a bacterial-type RNA polymerase promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript. BFO:0000015 process biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BFO_0000015 An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. GO:0001177 regulation of transcription open complex formation at RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001177 regulation of transcriptional open complex formation at RNA polymerase II promoter Any process that modulates the rate, frequency or extent of a process involved the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase II preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble. BFO:0000016 disposition biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BFO_0000016 GO:0001178 regulation of transcriptional start site selection at RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001178 regulation of transcriptional start site selection at RNA polymerase II promoter|regulation of transcription start site selection at RNA polymerase II promoter Any process that modulates the rate, frequency or extent of a process involved in the selection of the specific location within the template strand of an RNA polymerase II promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript. BFO:0000017 realizable entity biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BFO_0000017 A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances. GO:0001179 RNA polymerase I general transcription initiation factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001179 RNA polymerase I transcription factor binding Interacting selectively and non-covalently with an RNA polymerase I transcription factor, any protein required to initiate or regulate transcription by RNA polymerase I. GO:0001172 transcription, RNA-templated biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001172 transcription, RNA-dependent The cellular synthesis of RNA on a template of RNA. GO:0001173 DNA-templated transcriptional start site selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001173 DNA-dependent transcriptional start site selection Any process involved in the selection of the specific location within the template strand of a DNA-dependent RNA polymerase promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript. GO:0001174 transcriptional start site selection at RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001174 Any process involved in the selection of the specific location within the template strand of an RNA polymerase II promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript. GO:0001175 transcriptional start site selection at RNA polymerase III promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001175 Any process involved in the selection of the specific location within the template strand of an RNA polymerase III promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript. GO:0001170 obsolete transcription factor activity, RNA polymerase I enhancer sequence-specific binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001170 RNA polymerase I enhancer sequence-specific DNA binding transcription factor activity OBSOLETE. Interacting selectively and non-covalently with a RNA polymerase I (Pol I) enhancer in order to modulate transcription by RNA polymerase I. GO:0001171 reverse transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001171 Wikipedia:Reverse_transcription A DNA synthesis process that uses RNA as the initial template for synthesis of DNA, but which also includes an RNase activity to remove the RNA strand of an RNA-DNA heteroduplex produced by the RNA-dependent synthesis step and use of the initial DNA strand as a template for DNA synthesis. CHEBI:52070 senecionine N-oxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52070 CHEBI:134467 L-vinylglycine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134467 CHEBI:134464 [(2->6)-beta-D-fructofuranosyl-]n alpha-D-glucopyranoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_134464 CHEBI:52079 N-acetyl-D-hexosamine 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52079 CHEBI:52075 all-trans-13,14-dihydroretinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52075 CHEBI:52076 gibberellin A3 O-beta-D-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52076 GO:1990200 SsuD-SsuE complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990200 two-component alkanesulfonate monooxygenase system A protein complex containing an alkanesulfonate monooxygenase subunit (SsuD tetramer in E.coli) and a flavin oxidoreductase subunit (SsuE dimer in E.coli). Involved in the utilization of alkanesulfonates as sulfur sources under conditions of sulfate or cysteine starvation. GO:1990201 alkanesulfonate monooxygenase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990201 SsuD complex A protein complex capable of alkanesulfonate monooxygenase activity. Involved in the utilization of alkanesulfonates as sulfur sources under conditions of sulfate or cysteine starvation, catalyzing the conversion of alkanesulfonates into aldehydes and sulfite. In E.coli the complex consists of a SsuD tetramer. GO:1990202 FMN reductase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990202 FMN reductase complex, NAD(P)H-dependent|FMN oxidoreductase complex, NAD(P)H-dependent|flavin oxidoreductase complex, NAD(P)H-dependent|SsuE complex A protein complex capable of FMN reductase activity. Reduces FMN to FMNH2 in a NAD(P)H-dependent manner. In E.coli, consists of a SsuE dimer. GO:1990203 MdtBC Complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990203 multidrug efflux pump MdtBC A protein complex containing two transmembrane subunits; a MdtB dimer and one unit of MdtC. Capable of exporting substrates across the cell membrane. Involved in conferring antibiotic resistance of Gram-negative bacteria by transporting drugs across the membrane. BFO:0000004 independent continuant biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BFO_0000004 A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything. GO:0001187 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001187 GO:0001188 RNA polymerase I preinitiation complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001188 RNA polymerase I transcriptional preinitiation complex assembly|RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nucleolar primary rRNA transcript|RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription from an RNA polymerase I promoter. GO:0001189 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001189 GO:0001183 transcription elongation from RNA polymerase I promoter for nuclear large rRNA transcript biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001183 The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase I promoter for the nuclear large ribosomal RNA (rRNA) transcript by the addition of ribonucleotides catalyzed by RNA polymerase I. GO:0001184 promoter clearance from RNA polymerase I promoter for nuclear large rRNA transcript biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001184 Any process involved in the transition from the initiation to the elongation phases of transcription by RNA polymerase I at a promoter for the nuclear large ribosomal RNA (rRNA) transcript, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors. GO:0001185 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001185 GO:0001186 obsolete RNA polymerase I transcription regulator recruiting activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001186 transcription factor activity, RNA polymerase I transcription factor recruiting|RNA polymerase I transcription factor recruiting transcription factor activity|RNA polymerase I transcription factor recruiting activity OBSOLETE. The function of binding to an RNA polymerase I (RNAP I) transcription regulator and recruiting it to the general transcription machinery complex in order to modulate transcription initiation. GO:0001180 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001180 GO:0001181 RNA polymerase I general transcription initiation factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001181 transcription factor activity, core RNA polymerase I binding|RNA polymerase I transcription general initiation factor activity|core RNA polymerase I binding transcription factor activity|general RNA polymerase I transcription factor activity A general transcription initiation factor activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase I. Factors required for RNA polymerase I transcription initiation include upstream activation factor (UAF), core factor (CF), TATA binding protein (TBP) and RRN3. In all species characterized, RNA polymerase I transcribes a large polycistronic transcript that is processed into several mature rRNAs (3 or 4 depending on the species), including the large subunit rRNA (28S in humans), the small subunit rRNA (18S in humans), as well as one or two additional smaller rRNAs (the 5.8S rRNA in humans). In most species, this large rRNA transcript is the sole product of RNA polymerase I. However there are rare exceptions, such as Trypanosoma brucei, where RNA polymerase I also transcribes certain mRNAs. GO:0001182 promoter clearance from RNA polymerase I promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0001182 Any process involved in the transition from the initiation to the elongation phases of transcription by RNA polymerase I, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors. CHEBI:134477 N-acetyl-L-methionyl-L-leucine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134477 CHEBI:134478 N-acetyl-L-methionyl-L-isoleucine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134478 CHEBI:52061 5-methoxyfurocoumarin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52061 GO:1990208 positive regulation by symbiont of RNA levels in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990208 Any process in which an organism activates, maintains or increases the frequency, rate or extent of the RNA levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:1990209 negative regulation by symbiont of RNA levels in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990209 Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the RNA levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. BFO:0000002 continuant biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BFO_0000002 An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts. CHEBI:52069 3,5-dihydroxybiphenyl biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52069 BFO:0000003 occurrent biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BFO_0000003 An entity that has temporal parts and that happens, unfolds or develops through time. GO:1990204 oxidoreductase complex biolink:CellularComponent go-plus goslim_metagenomics http://purl.obolibrary.org/obo/GO_1990204 redox complex|oxidation-reduction complex Any protein complex that possesses oxidoreductase activity. GO:1990205 taurine dioxygenase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990205 alpha-ketoglutarate-dependent taurine dioxygenase complex|2-aminoethanesulfonate dioxygenase complex|TauD complex A protein complex capable of catalyzing the conversion of taurine and alpha-ketoglutarate to sulfite, aminoacetaldehyde and succinate under sulfur or cysteine starvation conditions. Its expression is repressed by the presence of sulfate or cysteine. In E. coli it is a homodimer or homotetramer of the protein TauD. GO:1990206 jasmonyl-Ile conjugate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990206 JA-Ile hydrolase Catalysis of the reaction: jasmonyl-Ile + H2O = jasmonic acid + L-isoleucine. CHEBI:134471 N-acetyl-L-methionyl-L-glutamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134471 GO:1990207 EmrE multidrug transporter complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990207 EmrE complex A transmembrane protein complex capable of transporting positively charged hydrophobic drugs across the plasma membrane thereby involved in conferring resistance to a wide range of toxic compounds (e.g. methyl viologen, ethidium bromide and acriflavine). It is commonly found in bacteria. In E. coli it forms a homodimer. CHEBI:134472 N-acyl-alpha-aminoacyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134472 GO:0001158 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001158 GO:1990211 positive regulation by symbiont of jasmonic acid levels in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990211 Any process in which an organism activates, maintains or increases the frequency, rate or extent of the jasmonic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0001159 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001159 GO:1990212 positive regulation by symbiont of ethylene levels in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990212 Any process in which an organism activates, maintains or increases the frequency, rate or extent of the ethylene levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:1990213 negative regulation by symbiont of salicylic acid levels in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990213 Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of salicylic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:1990214 obsolete negative regulation by symbiont of host protein levels biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990214 OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of protein levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0001154 TFIIIB-class transcription factor complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001154 TFIIIB-class transcription factor binding Interacting selectively and non-covalently with a general RNA polymerase III transcription factor belonging to the TFIIB complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase III. GO:0001155 TFIIIA-class transcription factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001155 Interacting selectively and non-covalently with an RNA polymerase III transcription factor of the TFIIIA class, one of the factors involved in formation of the preinitiation complex (PIC) at RNA polymerase III promoters. GO:0001156 TFIIIC-class transcription factor complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001156 TFIIIC-class transcription factor binding Interacting selectively and non-covalently with a general RNA polymerase III transcription factor belonging to the TFIIC complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase III. GO:0001157 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001157 GO:1990210 positive regulation by symbiont of indole acetic acid levels in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990210 positive regulation by symbiont of IAA levels in host|positive regulation by symbiont of auxin levels in host Any process in which an organism activates, maintains or increases the frequency, rate or extent of the indole acetic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0001150 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001150 GO:0001151 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001151 GO:0001152 obsolete transcription factor activity, RNA polymerase III type 1 promoter sequence-specific binding, TFIIIC recruiting biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001152 TFIIIA activity|RNA polymerase III type 1 promoter sequence-specific DNA binding TFIIIC recruiting transcription factor activity|type 1 RNA polymerase III promoter recognition OBSOLETE. The function of binding to a specific DNA sequence motif in a type 1 RNA polymerase III (Pol III) promoter in order to recruit the transcription factor TFIIIC to the promoter. GO:0001153 obsolete transcription factor activity, RNA polymerase III transcription factor recruiting biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001153 RNA polymerase III transcription factor recruiting transcription factor activity OBSOLETE. The function of binding to an RNA polymerase III (RNAP III) transcription factor and recruiting it to the transcription machinery complex in order to modulate transcription by RNAP III. CHEBI:27096 trichlorobenzene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27096 CHEBI:27097 trichlorocatechol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_27097 GO:0015799 propanediol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015799 The directed movement of propanediol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Propanediol is a sweet colorless, viscous, hygroscopic liquid used as an antifreeze and in brake fluid; it is also as a humectant in cosmetics and personal care items, although it can be absorbed through the skin with harmful effects. CHEBI:52050 (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52050 CHEBI:52051 benzyl acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52051 GO:0015795 sorbitol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015795 glucitol transport The directed movement of sorbitol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sorbitol, also known as glucitol, is the hexitol derived by the reduction of the aldehyde group of glucose. CHEBI:134448 phosphatidylglycerol 38:4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134448 GO:0015796 galactitol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015796 The directed movement of galactitol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Galactitol is the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose. GO:0015797 mannitol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015797 The directed movement of mannitol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Mannitol is the alditol derived from D-mannose by reduction of the aldehyde group. GO:0015798 myo-inositol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015798 vitamin Bh transport The directed movement of myo-inositol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Myo-inositol is 1,2,3,4,5/4,6-cyclohexanehexol, a growth factor for animals and microorganisms. GO:0015791 polyol transport biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0015791 The directed movement of polyols, any polyhydric alcohol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:1990219 obsolete positive regulation by symbiont of host protein levels biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990219 OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of protein levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0015792 arabinitol transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015792 arabitol transport|arabinitol transport The process in which arabitol is transported across a lipid bilayer, from one side of a membrane to the other. Arabitol is the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms. CHEBI:52057 N-acetylphosphinothricin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52057 BFO:0000034 function biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BFO_0000034 GO:0015793 glycerol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015793 The directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glycerol is 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids. CHEBI:52058 5-hydroxyfurocoumarin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52058 GO:0015794 glycerol-3-phosphate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015794 glycerol-3-phosphate transport The process in which glycerol-3-phosphate is transported across a membrane. Glycerol-3-phosphate is a phosphoric monoester of glycerol. GO:1990215 negative regulation by symbiont of host intracellular transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990215 Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of intracellular transport in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:52052 phenylacetone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_52052 GO:1990216 positive regulation by symbiont of host transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990216 Any process in which an organism activates, maintains or increases the frequency, rate or extent of transcription in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:1990217 suppression by symbiont of host phytoalexin production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990217 negative regulation by symbiont of host phytoalexin production Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of phytoalexin production in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0015790 UDP-xylose transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0015790 UDP-xylose transport The directed movement of UDP-xylose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-xylose is a substance composed of xylose in glycosidic linkage with uridine diphosphate. GO:1990218 positive regulation by symbiont of abscisic acid levels in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990218 Any process in which an organism activates, maintains or increases the frequency, rate or extent of the abscisic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:1990222 ProVWX complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990222 ATP-binding cassette (ABC) transporter complex ProVWX The ProVWX complex belongs to the family of ATP-binding cassette (ABC) transporter proteins complexes. It consists of a cytoplasmic ATPase subunit ProV, a transmembrane subunit ProW and a periplasmic binding protein ProX. It is capable of translocating a wide variety of solute (e.g. glycine betaine) across the plasma membrane and is activated under osmotic stress conditions. GO:0001169 obsolete transcription factor activity, RNA polymerase I CORE element sequence-specific binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001169 RNA polymerase I core promoter sequence-specific DNA binding transcription factor|RNA polymerase I CORE element sequence-specific DNA binding transcription factor activity OBSOLETE. Interacting selectively and non-covalently with CORE element, a regulatory region composed of the transcription start site and binding sites for transcription factors of the RNA polymerase I transcription machinery in order to modulate transcription by RNA polymerase I. GO:1990223 positive regulation by symbiont of cytokinin levels in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990223 Any process in which an organism activates, maintains or increases the frequency, rate or extent of the cytokinin levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:1990224 NMN phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990224 RHEA:30815 nicotinamide mononucleotide phosphatase activity|beta-nicotinamide D-ribonucleotide phosphatase activity Catalysis of the reaction: beta-nicotinamide D-ribonucleotide (NMN-) + H2O = beta-nicotinamide D-riboside (nicotinamide ribose, NmR) + phosphate. GO:1990225 rhoptry neck biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990225 Narrow, electron-dense part of the rhoptry that extends through the conoid at the apical tip of an apicomplexan parasite. The rhoptry neck serves as a duct through which the contents of the rhoptry are secreted after attachment to the host has been completed and at the commencement of invasion. GO:0001165 RNA polymerase I cis-regulatory region sequence-specific DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001165 RNA polymerase I enhancer sequence-specific DNA binding|RNA polymerase I upstream element sequence-specific DNA binding|RNA polymerase I upstream control element sequence-specific DNA binding Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase I. RNA polymerase I elements are referred to either enhancers or upstream control element (UCE, or alternately referred to as the upstream element). CHEBI:52049 tetrachlorophenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52049 GO:0001166 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001166 GO:1990220 GroEL-GroES complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990220 bacterial chaperonin complex|bacterial chaperonin ATPase complex Bacterial chaperonin complex consisting of a heptameric 10kDa chaperonin subunit GroES and a tetradecameric (2x7) 60kDa chaperonin subunit GroEL. The 60kDa subunit possesses ATPase activity while the holo-enzyme is responsible for the correct folding of proteins. GO:0001167 obsolete RNA polymerase I transcription factor activity, sequence-specific DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001167 sequence-specific DNA binding RNA polymerase I transcription factor activity OBSOLETE. Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase I. The transcription factor may or may not also interact selectively with a protein or macromolecular complex. UBERON:5002544 digit plus metapodial segment biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_5002544 digit ray|digit ( phalanges plus metapodial) plus soft tissue|digit digitopodial subdivision|digit A subdivision of the autopod consisting of digit plus the region incorporating a single metapodial element. These segments are typically repeated along the pre-axiom to post-axial axis. GO:0001168 obsolete transcription factor activity, RNA polymerase I upstream control element sequence-specific binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001168 RNA polymerase I upstream control element sequence-specific DNA binding transcription factor activity OBSOLETE. Interacting selectively and non-covalently with the upstream control element (UCE, or alternately referred to as the upstream element, UE), a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase I in order to modulate transcription by RNA polymerase I. GO:1990221 L-cysteine desulfurase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990221 IscS|SufS complex|NIFS|NifS A protein complex capable of cysteine desulfurase activity decomposing L-cysteine to L-alanine and sulfur. It belongs to a ubiquitous family of pyridoxal 5-phosphate (PLP)-dependent enzymes. In E. coli it consists of a SufS dimer. GO:0001161 intronic transcription regulatory region sequence-specific DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001161 intronic transcription regulatory region DNA binding Interacting selectively and non-covalently with an intronic DNA sequence that regulates the transcription of the transcript it is contained within. GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001162 Interacting selectively and non-covalently with an RNA polymerase II intronic DNA sequence that regulates the transcription of the transcript it is contained within. GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001163 RNA polymerase I regulatory region DNA binding Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase I. GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0001164 RNA polymerase I core promoter sequence-specific DNA binding|transcription factor activity, RNA polymerase I CORE element binding transcription factor recruiting|RNA polymerase I CORE element sequence-specific DNA binding|RNA polymerase I core element sequence-specific DNA binding|RNA polymerase I CORE element sequence-specific DNA binding transcription factor recruiting transcription factor activity Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for transcription factors of the RNA polymerase I transcription machinery. This site is often referred to as the CORE element. In mammalian cells, the CORE element functions in conjunction with the Upstream Control Element (UCE), while in fungi, protozoa, and plants, the CORE element functions without a UCE. GO:0001160 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0001160 CHEBI:134456 12-oxo-20-hydroxyleukotriene B4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134456 CHEBI:134453 10-HETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_134453 CHEBI:52045 2-oxo-1,2-dihydroquinoline-4-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52045 BFO:0000023 role biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BFO_0000023 A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts. CHEBI:52048 2,3,5,6-tetrachlorophenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52048 GO:1990226 histone methyltransferase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1990226 Interacting selectively and non-covalently with a histone methyltransferase enzyme. GO:1990227 paranodal junction maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1990227 paranodal axoglial junction maintenance|paranodal septate maintenance|axoglial septate junction maintenance The maintenance of a paranodal junction, a highly specialized cell-cell junction found in vertebrates, which forms between a neuron and a glial cell, and has structural similarity to Drosophila septate junctions. A paranodal junction flanks the node of Ranvier in myelinated nerve, electrically isolates the myelinated from unmyelinated nerve segments, and physically separates the voltage-gated sodium channels at the node from the cluster of potassium channels underneath the myelin sheath. GO:1990228 sulfurtransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990228 SufE dimer|SufE complex|ThiF-ThiS complex|sulfur transfer complex A protein complex capable of catalyzing the transfer of sulfur atoms from one compound (donor) to another (acceptor). BFO:0000020 specifically dependent continuant biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BFO_0000020 A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same. CHEBI:52043 7-methyl-3-oxooct-6-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_52043 GO:1990229 iron-sulfur cluster assembly complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1990229 Fe-S cluster assembly complex|SufBCD complex A protein complex capable of assembling an iron-sulfur (Fe-S) cluster. GO:0019460 glutamine catabolic process to fumarate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019460 glutamine degradation to fumarate|glutamine breakdown to fumarate|glutamate catabolic process to fumarate The chemical reactions and pathways resulting in the breakdown of glutamine into other compounds, including fumarate. GO:0044423 virion part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044423 Any constituent part of a virion, a complete fully infectious extracellular virus particle. GO:0044424 obsolete intracellular part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044424 OBSOLETE. Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm. GO:0044421 obsolete extracellular region part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044421 NIF_Subcellular:sao9117790637 extracellular structure OBSOLETE. Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite. GO:0044422 obsolete organelle part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044422 OBSOLETE. Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane. GO:0044420 obsolete extracellular matrix component biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044420 extracellular matrix part OBSOLETE. Any constituent part of the extracellular matrix, the structure lying external to one or more cells, which provides structural support for cells or tissues; may be completely external to the cell (as in animals) or be part of the cell (as often seen in plants). GO:0044429 obsolete mitochondrial part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044429 NIF_Subcellular:sao666410040 mitochondrial subcomponent|mitochondrion component OBSOLETE. Any constituent part of a mitochondrion, a semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. GO:0044427 obsolete chromosomal part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044427 chromosome component|chromosomal component|chromosome part OBSOLETE. Any constituent part of a chromosome, a structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. GO:0044428 obsolete nuclear part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044428 NIF_Subcellular:sao1499850686 nucleus component|nuclear subcomponent OBSOLETE. Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. GO:0019458 methionine catabolic process via 2-oxobutanoate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019458 MetaCyc:PWY-701 methionine breakdown via 2-oxobutanoate|methionine degradation via 2-oxobutanoate The chemical reactions and pathways resulting in the breakdown of methionine, via the intermediate 2-oxobutanoate. GO:0044425 obsolete membrane part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044425 OBSOLETE. Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. GO:0044426 obsolete cell wall part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044426 OBSOLETE. Any constituent part of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. GO:0019459 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019459 GO:0019456 L-cysteine catabolic process via cystine, using cysteine transaminase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019456 L-cysteine breakdown via cystine, using cysteine transaminase|L-cysteine degradation via cystine, using cysteine transaminase The chemical reactions and pathways resulting in the breakdown, via the compound cystine, of L-cysteine, catalyzed by the enzyme cysteine transaminase (EC:2.6.1.3). GO:0019457 methionine catabolic process to succinyl-CoA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019457 MetaCyc:METHIONINE-DEG1-PWY methionine degradation to succinyl-CoA|methionine breakdown to succinyl-CoA The chemical reactions and pathways resulting in the breakdown of methionine into other compounds, including succinyl-CoA. GO:0019454 L-cysteine catabolic process via cystine, using glutathione-cystine transhydrogenase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019454 L-cysteine degradation via cystine, using glutathione-cystine transhydrogenase|L-cysteine breakdown via cystine, using glutathione-cystine transhydrogenase The chemical reactions and pathways resulting in the breakdown, via the compound cystine, of L-cysteine, catalyzed by the enzyme glutathione-cystine transhydrogenase (EC:1.8.4.4). GO:0019455 L-cysteine catabolic process via cystine, using cystine reductase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019455 L-cysteine breakdown via cystine, using cystine reductase|L-cysteine degradation via cystine, using cystine reductase The chemical reactions and pathways resulting in the breakdown, via the compound cystine, of L-cysteine, catalyzed by the enzyme cystine reductase (EC:1.8.1.6). GO:0019452 L-cysteine catabolic process to taurine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019452 L-cysteine degradation to taurine|L-cysteine breakdown to taurine The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including taurine. GO:0019453 L-cysteine catabolic process via cystine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019453 L-cysteine degradation via cystine|L-cysteine breakdown via cystine The chemical reactions and pathways resulting in the breakdown of L-cysteine, via the intermediate cystine. GO:0019450 L-cysteine catabolic process to pyruvate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019450 MetaCyc:LCYSDEG-PWY L-cysteine degradation to pyruvate|L-cysteine breakdown to pyruvate The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including pyruvate. GO:0019451 L-cysteine catabolic process to pyruvate, using cysteine dioxygenase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019451 MetaCyc:CYSTEINE-DEG-PWY L-cysteine degradation to pyruvate, using cysteine dioxygenase|L-cysteine breakdown to pyruvate, using cysteine dioxygenase The chemical reactions and pathways resulting in the breakdown into pyruvate of L-cystine, catalyzed by the enzyme cysteine dioxygenase (EC:1.13.11.20). GO:0019470 4-hydroxyproline catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019470 MetaCyc:HYDROXYPRODEG-PWY 4-hydroxyproline degradation|4-hydroxyproline breakdown|4-hydroxyproline catabolism The chemical reactions and pathways resulting in the breakdown of 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline. GO:0019471 4-hydroxyproline metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019471 4-hydroxyproline metabolism The chemical reactions and pathways involving 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline. The presence of hydroxyproline is essential to produce stable triple helical tropocollagen, hence the problems caused by ascorbate deficiency in scurvy. This unusual amino acid is also present in considerable amounts in the major glycoprotein of primary plant cell walls. GO:0044434 obsolete chloroplast part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044434 OBSOLETE. Any constituent part of a chloroplast, a chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. CHEBI:140785 alkylcob(III)alamin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140785 GO:0044435 obsolete plastid part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044435 OBSOLETE. Any constituent part of a plastid, a member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid. GO:0044432 obsolete endoplasmic reticulum part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044432 ER component OBSOLETE. Any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. GO:0044433 obsolete cytoplasmic vesicle part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044433 OBSOLETE. Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell. GO:0044430 obsolete cytoskeletal part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044430 NIF_Subcellular:sao1635329413 cytoskeleton component|cytoskeletal element OBSOLETE. Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice. GO:0044431 obsolete Golgi apparatus part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044431 NIF_Subcellular:sao624292949 Golgi subcomponent|Golgi component OBSOLETE. Any constituent part of the Golgi apparatus, a compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. GO:0044438 obsolete microbody part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044438 OBSOLETE. Any constituent part of a microbody, a cytoplasmic organelle, spherical or oval in shape, that is bounded by a single membrane and contains oxidative enzymes, especially those utilizing hydrogen peroxide (H2O2). GO:0044439 obsolete peroxisomal part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044439 peroxisome component OBSOLETE. Any constituent part of a peroxisome, a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules; contains some enzymes that produce and others that degrade hydrogen peroxide (H2O2). GO:0044436 obsolete thylakoid part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044436 OBSOLETE. Any constituent part of a thylakoid, a sac-like vesicle that bears the photosynthetic pigments in photosynthetic organisms. GO:0019469 octopine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019469 MetaCyc:OCTOPINEDEG-PWY octopine degradation|octopine breakdown|octopine catabolism The chemical reactions and pathways resulting in the breakdown of octopine (N-(1-carboxy-4-guanidinobutyl)-L-alanine), an amino acid derived opine. GO:0044437 obsolete vacuolar part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044437 vacuole component OBSOLETE. Any constituent part of a vacuole, a closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. GO:0019467 ornithine catabolic process, by decarboxylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019467 MetaCyc:ORNDEG-PWY ornithine degradation, by decarboxylation|ornithine breakdown, by decarboxylation The chemical reactions and pathways resulting in the breakdown of ornithine by decarboxylation. GO:0019468 nopaline catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019468 MetaCyc:NOPALINEDEG-PWY nopaline catabolism|nopaline breakdown|nopaline degradation The chemical reactions and pathways resulting in the breakdown of nopaline (N-(I-carboxy-4-guanidinobutyl)glutamic acid), a rare amino-acid derivative. GO:0019465 aspartate transamidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019465 MetaCyc:ASPARTATE-DEG1-PWY|MetaCyc:ASPARTATESYN-PWY The exchange of the amino group of aspartate, the anion derived from aspartic acid, for another amino group. GO:0019466 ornithine catabolic process via proline biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019466 MetaCyc:ORN-AMINOPENTANOATE-CAT-PWY ornithine degradation via proline|ornithine breakdown via proline The chemical reactions and pathways resulting in the breakdown of ornithine, via the intermediate proline. GO:0019463 glycine catabolic process to creatine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019463 MetaCyc:GLYCGREAT-PWY glycine degradation to creatine|glycine breakdown to creatine The chemical reactions and pathways resulting in the breakdown of glycine into other compounds, including creatine. GO:0019464 glycine decarboxylation via glycine cleavage system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019464 MetaCyc:GLYCLEAV-PWY glycine cleavage system The chemical reactions and pathways resulting in the breakdown of glycine by oxidative cleavage to carbon dioxide, ammonia, and a methylene group, mediated by enzymes of the glycine cleavage complex. GO:0019461 glutamine catabolic process to fumarate, using glutamate synthase (NADPH) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019461 MetaCyc:GLUTAMINEFUM-PWY glutamine breakdown to fumarate, using glutamate synthase (NADPH)|glutamate catabolic process to fumarate, using glutamate synthase (NADPH)|glutamine degradation to fumarate, using glutamate synthase (NADPH) The chemical reactions and pathways resulting in the breakdown of glutamine into fumarate, beginning with the conversion of glutamine to glutamate catalyzed by the enzyme glutamate synthase (NADPH) (EC:1.4.1.13). GO:0019462 glutamine catabolic process to fumarate, using glutaminase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019462 MetaCyc:GLUTAMINDEG-PWY glutamate catabolic process to fumarate, using glutaminase|glutamine degradation to fumarate, using glutaminase|glutamine breakdown to fumarate, using glutaminase The chemical reactions and pathways resulting in the breakdown of glutamine into fumarate, beginning with conversion of glutamine into glutamate catalyzed by the enzyme glutaminase (EC:3.5.1.2). GO:0044445 obsolete cytosolic part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044445 cytosol component OBSOLETE. Any constituent part of cytosol, that part of the cytoplasm that does not contain membranous or particulate subcellular components. CHEBI:140773 lysophosphatidylcholine P-16:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140773 CHEBI:140774 4-[(1->4)-alpha-D-glucosyl]n-D-glucose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140774 GO:0044446 obsolete intracellular organelle part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044446 OBSOLETE. A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane. GO:0044443 obsolete pilus part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044443 pilus component|fimbrium component|fimbrial part OBSOLETE. Any constituent part of a pilus, a proteinaceous hair-like appendage on the surface of bacteria ranging from 2-8 nm in diameter. GO:0044444 obsolete cytoplasmic part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044444 cytoplasm component OBSOLETE. Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0044441 obsolete ciliary part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044441 flagellar part|microtubule-based flagellum part|flagellum part|cilial part|cilium part|flagellum component OBSOLETE. Any constituent part of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole. GO:0044442 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044442 GO:0044440 obsolete endosomal part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044440 NIF_Subcellular:sao1683772610 endosomal subcomponent|endosome component OBSOLETE. Any constituent part of an endosome, a membrane-bounded organelle to which materials ingested by endocytosis are delivered. GO:0019438 aromatic compound biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019438 aromatic compound formation|aromatic compound biosynthesis|aromatic hydrocarbon biosynthesis|aromatic hydrocarbon biosynthetic process|aromatic compound anabolism|aromatic compound synthesis The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring. GO:0044449 obsolete contractile fiber part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044449 muscle fiber component|contractile fibre component|muscle fibre component OBSOLETE. Any constituent part of a contractile fiber, a fiber composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle. GO:0019439 aromatic compound catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019439 aromatic compound catabolism|aromatic hydrocarbon catabolism|aromatic hydrocarbon catabolic process|aromatic compound degradation|aromatic compound breakdown The chemical reactions and pathways resulting in the breakdown of aromatic compounds, any substance containing an aromatic carbon ring. GO:0044447 obsolete axoneme part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044447 axonemal part OBSOLETE. Any constituent part of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements. GO:0019436 sophorosyloxydocosanoate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019436 MetaCyc:SOPHOROSYLOXYDOCOSANOATE-DEG-PWY sophorosyloxydocosanoate degradation|sophorosyloxydocosanoate breakdown|sophorosyloxydocosanoate catabolism The chemical reactions and pathways resulting in the breakdown of sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate. CHEBI:140775 1-[(1->4)-alpha-D-glucosyl]n-alpha-D-glucopyranoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140775 GO:0044448 obsolete cell cortex part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044448 OBSOLETE. Any constituent part of the cell cortex, the region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins. GO:0019434 sophorosyloxydocosanoate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019434 sophorosyloxydocosanoate metabolism The chemical reactions and pathways involving sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate, an aromatic hydrocarbon. GO:0019435 sophorosyloxydocosanoate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019435 MetaCyc:SOPHOROSYLOXYDOCOSANOATE-SYN-PWY sophorosyloxydocosanoate synthesis|sophorosyloxydocosanoate formation|sophorosyloxydocosanoate anabolism|sophorosyloxydocosanoate biosynthesis The chemical reactions and pathways resulting in the formation of sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate. GO:0019432 triglyceride biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019432 MetaCyc:TRIGLSYN-PWY triglyceride anabolism|triglyceride synthesis|triglyceride formation|triacylglycerol biosynthetic process|triacylglycerol biosynthesis|triglyceride biosynthesis The chemical reactions and pathways resulting in the formation of a triglyceride, any triester of glycerol. GO:0019433 triglyceride catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019433 MetaCyc:LIPAS-PWY triacylglycerol catabolism|triacylglycerol catabolic process|triglyceride catabolism|triglyceride degradation|triglyceride breakdown The chemical reactions and pathways resulting in the breakdown of a triglyceride, any triester of glycerol. GO:0019430 removal of superoxide radicals biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019430 MetaCyc:DETOX1-PWY cellular detoxification of superoxide radicals|removal of O2-|removal of oxygen free radicals Any process, acting at the cellular level, involved in removing superoxide radicals (O2-) from a cell or organism, e.g. by conversion to dioxygen (O2) and hydrogen peroxide (H2O2). GO:0019431 acetyl-CoA biosynthetic process from ethanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019431 MetaCyc:ETOH-ACETYLCOA-ANA-PWY acetyl-CoA formation from ethanol|acetyl-CoA synthesis from ethanol|acetyl-CoA anabolism from ethanol The chemical reactions and pathways resulting in the formation of acetyl-CoA from ethanol via acetaldehyde. GO:0044456 obsolete synapse part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044456 NIF_Subcellular:sao1784069613 synaptic component OBSOLETE. Any constituent part of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. GO:0044457 obsolete cell septum part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044457 OBSOLETE. Any constituent part of a cell septum, a structure composed of peptidoglycan and often chitin in addition to other materials. It usually forms perpendicular to the long axis of a cell or hypha and grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells. GO:0044454 obsolete nuclear chromosome part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044454 OBSOLETE. Any constituent part of a nuclear chromosome, a chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact. GO:0044455 obsolete mitochondrial membrane part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044455 OBSOLETE. Any constituent part of a mitochondrial membrane, either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope. GO:0044452 obsolete nucleolar part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044452 nucleolus component OBSOLETE. Any constituent part of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. GO:0044453 obsolete nuclear membrane part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044453 OBSOLETE. Any constituent part of the nuclear membrane, the envelope that surrounds the nucleus of eukaryotic cells. GO:0044450 obsolete microtubule organizing center part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044450 MTOC component|microtubule organizing centre component OBSOLETE. Any constituent part of a microtubule organizing center, a region in a eukaryotic cell, such as a centrosome or basal body, from which microtubules grow. CHEBI:43098 heptane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_43098 GO:0044451 obsolete nucleoplasm part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044451 OBSOLETE. Any constituent part of the nucleoplasm, that part of the nuclear content other than the chromosomes or the nucleolus. GO:0019449 L-cysteine catabolic process to hypotaurine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019449 L-cysteine breakdown to hypotaurine|L-cysteine degradation to hypotaurine The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including hypotaurine. GO:0044458 motile cilium assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044458 motile primary cilium assembly|motile primary cilia formation|nodal cilium formation|motile primary cilium formation|nodal cilium assembly|motile primary cilia assembly The aggregation, arrangement and bonding together of a set of components to form a motile cilium. GO:0019447 D-cysteine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019447 D-cysteine degradation|D-cysteine breakdown|D-cysteine catabolism The chemical reactions and pathways resulting in the breakdown of D-cysteine, (S)-2-amino-3-mercaptopropanoic acid, which occurs naturally in firefly luciferin. CHEBI:140764 beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-alpha-D-galactosaminide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140764 GO:0019448 L-cysteine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019448 L-cysteine catabolism|L-cysteine degradation|L-cysteine breakdown The chemical reactions and pathways resulting in the breakdown of L-cysteine, the L-enantiomer of 2-amino-3-mercaptopropanoic acid, i.e. (2R)-2-amino-3-mercaptopropanoic acid. GO:0044459 obsolete plasma membrane part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044459 OBSOLETE. Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. GO:0019445 tyrosine catabolic process to fumarate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019445 MetaCyc:TYRFUMCAT-PWY tyrosine degradation to fumarate|tyrosine breakdown to fumarate The chemical reactions and pathways resulting in the breakdown of tyrosine into other compounds, including fumarate. GO:0019446 obsolete tyrosine catabolic process to phosphoenolpyruvate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019446 tyrosine breakdown to phosphoenolpyruvate|tyrosine degradation to phosphoenolpyruvate OBSOLETE. The chemical reactions and pathways resulting in the breakdown of tyrosine into other compounds, including phosphoenolpyruvate. GO:0019443 obsolete tryptophan catabolic process, using tryptophanase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019443 tryptophan catabolic process, using tryptophanase|tryptophan breakdown, using tryptophanase|tryptophan degradation, using tryptophanase OBSOLETE. The chemical reactions and pathways resulting in the breakdown of tryptophan, catalyzed by the enzyme tryptophanase (EC:4.1.99.1). GO:0019444 tryptophan catabolic process to catechol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019444 MetaCyc:TRPCAT-PWY tryptophan breakdown to catechol|tryptophan degradation to catechol The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including catechol. GO:0019441 tryptophan catabolic process to kynurenine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019441 MetaCyc:TRPKYNCAT-PWY tryptophan degradation to kynurenine|tryptophan breakdown to kynurenine The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including kynurenine. GO:0019442 tryptophan catabolic process to acetyl-CoA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019442 MetaCyc:TRYPTOPHAN-DEGRADATION-1 tryptophan degradation to acetyl-CoA|tryptophan breakdown to acetyl-CoA The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including acetyl-CoA. GO:0019440 tryptophan catabolic process to indole-3-acetate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019440 MetaCyc:TRPIAACAT-PWY tryptophan catabolism to indoleacetic acid|tryptophan degradation to indole-3-acetate|tryptophan breakdown to indole-3-acetate|tryptophan catabolic process to indoleacetic acid|tryptophan catabolic process to IAA The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including indole-3-acetate. GO:0044460 obsolete flagellum part biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044460 flagellum part|flagellum component OBSOLETE. Any constituent part of a flagellum, a long whiplike or feathery structure borne either singly or in groups by the motile cells of many bacteria and unicellular eukaryotes and by the motile male gametes of many eukaryotic organisms, which propel the cell through a liquid medium. GO:0044467 glial cell-derived neurotrophic factor production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044467 glial cell-derived neurotrophic factor secretion|GDNF production|glial cell line-derived neurotrophic factor production The regulated release of glial cell line-derived neurotrophic factor from a cell. Glial cell-derived neurotrophic factor (GDNF) is a small protein that potently promotes the survival of many types of neurons, notably dopaminergic and motor neurons. GO:0044468 envenomation resulting in modulation of blood coagulation in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044468 envenomation resulting in regulation of blood coagulation in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the modulation of the frequency, rate or extent of blood coagulation in the bitten organism. GO:0044465 modulation of sensory perception of pain in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044465 regulation of sensory perception of pain in another organism A process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal, in a different organism. GO:0044466 glutaryl-CoA hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044466 EC:3.1.2.3 glutaryl-CoA thioesterase activity Catalysis of the reaction: glutaryl-CoA + H2O = CoA + glutarate. CHEBI:140750 D-5-phenylhydantoin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140750 GO:0044463 obsolete cell projection part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044463 OBSOLETE. Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon. GO:0044464 obsolete cell part biolink:CellularComponent go-plus gocheck_do_not_annotate|goslim_pir http://purl.obolibrary.org/obo/GO_0044464 NIF_Subcellular:sao628508602 cellular subcomponent|protoplast OBSOLETE. Any constituent part of a cell, the basic structural and functional unit of all organisms. GO:0044461 obsolete bacterial-type flagellum part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044461 flagellin-based flagellum part OBSOLETE. Any constituent part of the bacterial-type flagellum, a 20 nm diameter filament composed of subunits of flagellin driven passively at its base by a motor powered by a transmembrane ion potential, typically a proton or sodium potential. CHEBI:43088 N(5)-[(hydroxyamino)(imino)methyl]-L-ornithine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_43088 GO:0044462 obsolete external encapsulating structure part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044462 OBSOLETE. Any constituent part of an external encapsulating structure, a structure that lies outside the plasma membrane and surrounds the entire cell. This does not include the periplasmic space but does include the outer membrane (of gram negative bacteria) or cell wall (of yeast or Gram positive bacteria). GO:0019418 sulfide oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019418 MetaCyc:P222-PWY sulphide oxidation The chemical reactions and pathways resulting in the conversion of sulfide to elemental sulfur in a higher oxidation state, or to sulfite or sulfate. GO:0019419 sulfate reduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019419 sulphate reduction|sulphate reduction, APS pathway|sulfate reduction, APS pathway|assimilatory sulphate reduction|assimilatory sulfate reduction The chemical reactions and pathways resulting in the reduction of sulfate to another sulfur-containing ion or compound such as hydrogen sulfide, adenosine-phosphosulfate (APS) or thiosulfate. CHEBI:140758 N-carbamoyl-D-phenylglycine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140758 GO:0019416 polythionate oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019416 MetaCyc:THIOSULFOX-PWY The chemical reactions and pathways resulting in the conversion of thiosulfate to tetrathionate, using cytochrome c as an electron acceptor. GO:0019417 sulfur oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019417 sulphur oxidation The chemical reactions and pathways resulting the addition of oxygen to elemental sulfur. GO:0044469 envenomation resulting in positive regulation of blood coagulation in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044469 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant activation, maintenance or an increase in the frequency, rate or extent of blood coagulation in the bitten organism. GO:0019414 aerobic respiration, using sulfur or sulfate as electron donor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019414 aerobic respiration, using sulphur or sulphate as electron donor An aerobic respiration process in which a sulfur-containing molecule (hydrogen sulfide, sulfur, sulfite, thiosulfate, and various polythionates) is oxidized. GO:0019415 acetate biosynthetic process from carbon monoxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019415 acetate formation from carbon monoxide|acetate synthesis from carbon monoxide|acetate anabolism from carbon monoxide|carbon monoxide dehydrogenase pathway The chemical reactions and pathways resulting in the formation of acetate from other compounds, including carbon monoxide. GO:0019412 aerobic respiration, using hydrogen as electron donor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019412 MetaCyc:P283-PWY hydrogen oxidation The oxidation of hydrogen (H2) to water (H2O), using oxygen (O2) as the electron acceptor. A hydrogenase enzyme binds H2 and the hydrogen atoms are passed through an electron transfer chain to O2 to form water. GO:0019413 acetate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019413 acetate anabolism|acetate synthesis|acetate formation|acetate biosynthesis The chemical reactions and pathways resulting in the formation of acetate, the anion of acetic acid. GO:0019410 aerobic respiration, using carbon monoxide as electron donor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019410 The metabolic process in which carbon monoxide (CO) is oxidized to carbon dioxide (CO2) to generate energy. Conservation of energy in this process likely uses sodium ion gradients for ATP synthesis and is coupled to quantitative sulfide methylation. GO:0019411 aerobic respiration, using ferrous ions as electron donor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019411 The metabolic process in which ferrous ions (Fe2+) are oxidized to ferric ions (Fe3+) to generate energy, coupled to the reduction of carbon dioxide. GO:0044470 envenomation resulting in negative regulation of blood coagulation in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044470 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction in the frequency, rate or extent of blood coagulation in the bitten organism. CHEBI:43074 (3S)-3-hydroxy-3-methylglutaryl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_43074 GO:0044471 envenomation resulting in pore formation in membrane of other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044471 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the aggregation, arrangement and bonding together of a set of components to form a pore complex in a membrane of the bitten organism. GO:0044478 envenomation resulting in positive regulation of platelet aggregation in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044478 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant activation, maintenance or an increase in the frequency, rate or extent of platelet aggregation in the bitten organism. CHEBI:140741 hypotaurine(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_140741 GO:0044479 envenomation resulting in modulation of mast cell degranulation in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044479 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of blood mast cell degranulation in the bitten organism. GO:0044476 envenomation resulting in negative regulation of low voltage-gated calcium channel activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044476 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a low voltage-gated calcium channel in the bitten organism. GO:0044477 envenomation resulting in negative regulation of platelet aggregation in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044477 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction in the frequency, rate or extent of platelet aggregation in the bitten organism. GO:0044474 envenomation resulting in negative regulation of voltage-gated calcium channel activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044474 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a voltage-gated calcium channel in the bitten organism. GO:0044475 envenomation resulting in negative regulation of high voltage-gated calcium channel activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044475 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a high voltage-gated calcium channel in the bitten organism. GO:0044472 envenomation resulting in modulation of calcium channel activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044472 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of a calcium channel in the bitten organism. GO:0044473 envenomation resulting in negative regulation of calcium channel activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044473 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a calcium channel in the bitten organism. GO:0019429 fluorene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019429 MetaCyc:FLUORENE-DEG-9-ONE-PWY fluorene degradation|fluorene breakdown|fluorene catabolism The chemical reactions and pathways resulting in the breakdown of fluorene, a tricyclic polycyclic aromatic hydrocarbon containing a five-membered ring. It is a major component of fossil fuels and their derivatives and is also a by-product of coal-conversion and energy-related industries. It is commonly found in vehicle exhaust emissions, crude oils, motor oils, coal and oil combustion products, waste incineration, and industrial effluents. GO:0019427 acetyl-CoA biosynthetic process from acetate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019427 MetaCyc:ACETATEUTIL-PWY acetyl-CoA formation from acetate|acetyl-CoA synthesis from acetate|acetyl-CoA anabolism from acetate|acetate utilization The chemical reactions and pathways resulting in the formation of acetyl-CoA from acetate, either directly or via acetylphosphate. GO:0019428 allantoin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019428 MetaCyc:URSIN-PWY allantoin anabolism|allantoin synthesis|allantoin formation|allantoin biosynthesis The chemical reactions and pathways resulting in the formation of allantoin, (2,5-dioxo-4-imidazolidinyl)urea. GO:0019425 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019425 GO:0019426 bisulfite reduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019426 MetaCyc:P224-PWY bisulphite reduction The chemical reactions and pathways resulting in the reduction of sulfate to thiosulfate via bisulfite. CHEBI:140743 alpha-D-Gal-(1->3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140743 GO:0019423 sulfur oxidation, ferric ion-dependent biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019423 MetaCyc:FESULFOX-PWY sulphur oxidation, ferric ion-dependent A sulfur oxidation process that proceeds via the reaction catalyzed by sulfur:ferric ion oxidoreductase, and requires the presence of ferric ion (Fe3+). GO:0019424 sulfide oxidation, using siroheme sulfite reductase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019424 MetaCyc:P223-PWY sulphur oxidation, using siroheme sulphite reductase|sulfur oxidation, using sirohaem sulfite reductase|sulphide oxidation, using siroheme sulphite reductase|sulfide oxidation, using sirohaem sulfite reductase|sulfur oxidation, using siroheme sulfite reductase A sulfide oxidation process that proceeds via the reaction catalyzed by siroheme sulfite reductase. GO:0019421 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019421 GO:0019422 disproportionation of elemental sulfur biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019422 MetaCyc:P203-PWY disproportionation of elemental sulphur The process in which sulfur compounds with an intermediate oxidation state serve as both electron donors and electron acceptors in an energy-generating redox process. The reaction takes place anaerobically, in light and in the absence of CO2. GO:0019420 dissimilatory sulfate reduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019420 MetaCyc:DISSULFRED-PWY dissimilatory sulphate reduction The reduction of sulfate to hydrogen sulfide, which acts as a terminal electron acceptor. Sulfate is activated to adenosine-phosphosulfate (APS) which is then reduced to sulfite, which is in turn reduced to hydrogen sulfide. GO:0044481 envenomation resulting in proteolysis in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044481 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant hydrolysis of proteins in of the bitten organism. GO:0044482 envenomation resulting in blood vessel extracellular matrix damage, causing hemorrhagic damage in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044482 envenomation resulting in blood vessel ECM, causing hemorrhagic damage in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism which causes damage to the extracellular matrix of the blood vessels of the bitten organism, ultimately resulting in hemorrhage in the bitten organism. GO:0044480 envenomation resulting in positive regulation of mast cell degranulation in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044480 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of blood mast cell degranulation in the bitten organism. GO:0044489 negative regulation of voltage-gated sodium channel activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044489 Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism. GO:0044487 envenomation resulting in modulation of transmission of nerve impulse in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044487 envenomation resulting in modulation of conduction of nerve impulse in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of the transmission of nerve impulses in the bitten organism. GO:0044488 modulation of voltage-gated sodium channel activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044488 Any process in which an organism effects a change in the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism. GO:0044485 envenomation resulting in fibrinogenolysis in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044485 The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with fibrinogenolysis, a process that degrades fibrinogen at a variety of Arg-Lys bonds, thus impairing fibrinogen clotting in the bloodstream of the bitten/stung organism. GO:0044486 modulation of transmission of nerve impulse in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044486 modulation of conduction of nerve impulse in other organism|regulation of transmission of nerve impulse in other organism The process in which an organism effects a change in the transmission of a nerve impulse in another organism. CHEBI:43065 (S)-3-phenyllactic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_43065 GO:0044483 envenomation resulting in impairment of hemostasis in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044483 envenomation resulting in negative regulation of hemostasis in other organism|envenomation, impairing hemostasis in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the inhibition of the process of hemostasis - the stopping of bleeding or the arrest of the circulation to an organ or part - in the bitten organism. GO:0044484 envenomation resulting in fibrinolysis in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044484 The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with fibrinolysis, a process that solubilizes fibrin, chiefly by the proteolytic action of plasmin, in the bloodstream of the bitten/stung organism. GO:0044492 envenomation resulting in modulation of voltage-gated sodium channel activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044492 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of a voltage-gated sodium channel in the bitten organism. GO:0044493 envenomation resulting in negative regulation of voltage-gated sodium channel activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044493 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a voltage-gated sodium channel in the bitten organism. GO:0044490 positive regulation of voltage-gated sodium channel activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044490 Any process that activates or increases the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism. GO:0044491 positive regulation of molecular function in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044491 Any process that activates or increases the frequency, rate or extent of the function of proteins in a second organism. GO:0044498 envenomation resulting in modulation of blood pressure in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044498 envenomation resulting in regulation of blood pressure in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of the force with which blood travels through the circulatory system of the bitten/stung organism. GO:0044499 envenomation resulting in positive regulation of blood pressure in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044499 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant increase of the force with which blood travels through the circulatory system of the bitten/stung organism. CHEBI:43056 L-gamma-glutamyl-S-nitroso-D-cysteinylglycine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_43056 GO:0044496 negative regulation of blood pressure in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044496 A process by which one organism decreases the force with which blood travels through the circulatory system of another organism. GO:0044497 positive regulation of blood pressure in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044497 A process by which one organism increases the force with which blood travels through the circulatory system of another organism. GO:0044494 envenomation resulting in positive regulation of voltage-gated sodium channel activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044494 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant activation or increase in the activity of the activity of a voltage-gated sodium channel in the bitten organism. GO:0044495 modulation of blood pressure in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044495 regulation of blood pressure in other organism A process by which one organism modulates the force with which blood travels through the circulatory system of another organism. CHEBI:57693 aldehydo-D-arabinose 5-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57693 GO:0019409 aerobic respiration, using ammonia as electron donor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019409 MetaCyc:AMMOXID-PWY aerobic ammonia oxidation to nitrite via hydrazine The metabolic process in which ammonia (NH3) is oxidized to nitrite (NO2) in the presence of oxygen; enzymatic reactions convert ammonia to hydrazine, and hydrazine to nitrite. CHEBI:57694 quercetin-7-olate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57694 GO:0019407 hexitol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019407 hexitol catabolism|hexitol degradation|hexitol breakdown The chemical reactions and pathways resulting in the breakdown of hexitols, any alditol with a chain of six carbon atoms in the molecule. CHEBI:57691 N(6)-acyl-L-lysine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57691 GO:0019408 dolichol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019408 dolichol anabolism|dolichol biosynthesis|dolichol synthesis|dolichol formation The chemical reactions and pathways resulting in the formation of dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units. CHEBI:57692 FAD(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57692 CHEBI:140725 4-Imidazolone-5-propanoate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_140725 GO:0019405 alditol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019405 alditol catabolism|alditol degradation|alditol breakdown The chemical reactions and pathways resulting in the breakdown of alditols, any polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group. GO:0019406 hexitol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019406 hexitol formation|hexitol biosynthesis|hexitol anabolism|hexitol synthesis The chemical reactions and pathways resulting in the formation of hexitols, any alditol with a chain of six carbon atoms in the molecule. CHEBI:57690 cis-4-hydroxy-D-proline zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57690 GO:0019403 galactitol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019403 galactitol biosynthesis|galactitol anabolism|galactitol synthesis|galactitol formation The chemical reactions and pathways resulting in the formation of galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose. GO:0019404 galactitol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019404 MetaCyc:GALACTITOLCAT-PWY galactitol degradation|galactitol breakdown|galactitol catabolism The chemical reactions and pathways resulting in the breakdown of galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose. GO:0019401 alditol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019401 alditol formation|alditol biosynthesis|alditol anabolism|alditol synthesis The chemical reactions and pathways resulting in the formation of alditols, any polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group. GO:0019402 galactitol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019402 galactitol metabolism The chemical reactions and pathways involving galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose. CHEBI:57699 L-histidinol(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57699 GO:0019400 alditol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019400 alditol metabolism The chemical reactions and pathways involving alditols, any polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group. CHEBI:57697 deaminohydroxyblasticidin S(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57697 CHEBI:57698 2-(acetamidomethylidene)succinate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57698 CHEBI:57695 D-ribitol 5-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57695 CHEBI:67010 L-kynureninate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67010 CHEBI:67011 folates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67011 CHEBI:67016 tetrahydrofolate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67016 CHEBI:67012 L-dopa(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67012 CHEBI:82643 N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1<->1')-ceramide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82643 CHEBI:67013 methyl-branched fatty acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67013 CHEBI:67014 dihydrofolates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67014 CHEBI:67015 N(omega)-methyl-L-argininate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67015 CHEBI:67021 N-docosanoylsphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67021 CHEBI:67022 lipoxin anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67022 CHEBI:67027 N-eicosanoylsphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67027 CHEBI:82657 deoxyhypusine(2+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82657 CHEBI:67023 N-(2-hydroxydocosanoyl)sphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67023 CHEBI:67026 lipoxin A4(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67026 CHEBI:67031 lipoxin B4(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67031 CHEBI:67032 O-phosphonatooxyserine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67032 CHEBI:67033 N-octodecanoylsphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67033 CHEBI:67039 prenylcysteinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67039 CHEBI:67034 N-(2-hydroxyoctadecanoyl)sphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67034 CHEBI:67035 N-octadecanoyl-4-hydroxysphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67035 CHEBI:67036 O-(N-acetylglucosamine-1-phosphonatooxy)-L-serine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67036 CHEBI:82663 elemental iron biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82663 CHEBI:67037 D-octopine(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67037 CHEBI:67042 N-hexadecanoylsphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67042 CHEBI:67043 N-(2-hydroxyhexadecanoyl)sphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67043 CHEBI:67040 S-adenosyl-L-methioninate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67040 CHEBI:82679 7-oxolithocholic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82679 CHEBI:67049 N(alpha),N(alpha),N(alpha)-trimethyl-L-histidinium(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67049 CHEBI:82678 3beta-hydroxy-7-oxo-5beta-cholan-24-oic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82678 CHEBI:67045 N-tetradecanoylsphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67045 PR:000008725 haptoglobin biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000008725 HP A protein that is a translation product of the human HP gene or a 1:1 ortholog thereof. CHEBI:67052 glyphosate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67052 CHEBI:67050 S-methyl-L-methioninate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67050 CHEBI:67051 phosphopantetheine anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67051 CHEBI:82687 5-(2-hydroxyethyl)-1,3-thiazole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82687 CHEBI:67058 lysophosphatidylcholine 20:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67058 CHEBI:82684 7-O-methylvitexin 2''-O-beta-L-rhamnoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82684 CHEBI:82685 Mo(=O)(=S)-molybdopterin cofactor(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82685 CHEBI:82682 vitexin 2''-O-beta-L-rhamnoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82682 CHEBI:82683 O-[2'-(5-phosphoribosyl)-3'-dephospho-CoA]-L-serine(3-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82683 CHEBI:82680 monounsaturated fatty acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82680 CHEBI:82681 3-methoxy-5-methyl-1-naphthoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82681 GO:0019498 n-octane oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019498 MetaCyc:P221-PWY The chemical reactions and pathways resulting in the conversion of n-octane to octanoyl-CoA. GO:0019499 cyanide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019499 cyanide metabolism The chemical reactions and pathways involving cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration, reacting with the ferric form of cytochrome aa3 and thus blocking the electron transport chain. GO:0019496 serine-isocitrate lyase pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019496 A one-carbon metabolic process in which acetyl-CoA is produced from formaldehyde and carbon dioxide. GO:0019497 hexachlorocyclohexane metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019497 hexachlorocyclohexane metabolism The chemical reactions and pathways involving hexachlorocyclohexane, a cyclohexane derivative with 6 chlorine atoms attached to the hexane ring. Hexachlorocyclohexane consists of a mixture of 8 different isomers and was used a commercial insecticide. It is persistent in the environment, causing serious soil pollution. GO:0019494 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019494 GO:0019495 proline catabolic process to 2-oxoglutarate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019495 proline catabolic process to 2-ketoglutarate|proline catabolic process to alpha-oxoglutarate|proline catabolism to alpha-ketoglutarate|proline degradation to 2-oxoglutarate|proline catabolism to 2-ketoglutarate|proline breakdown to 2-oxoglutarate|proline catabolism to alpha-oxoglutarate|proline catabolic process to alpha-ketoglutarate The chemical reactions and pathways resulting in the breakdown of proline into other compounds, including 2-oxoglutarate. CHEBI:67063 poly-beta-1,6-N-acetyl-D-glucosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67063 CHEBI:67064 phosphatidylcholine O-36:4 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67064 CHEBI:67062 lipo-chitin oligosaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67062 CHEBI:82697 N-(ADP-D-ribosyl)diphthamide(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82697 CHEBI:82695 2-[(3S)-3-carboxylato-3-(dimethylammonio)propyl]-L-histidine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82695 CHEBI:82696 diphthine betaine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82696 CHEBI:82693 2-[(3S)-3-carboxylato-3-(methylammonio)propyl]-L-histidine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82693 GO:0019481 L-alanine catabolic process, by transamination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019481 MetaCyc:ALANINE-DEG3-PWY L-alanine degradation, by transamination|L-alanine breakdown, by transamination The chemical reactions and pathways resulting in the breakdown of L-alanine by transamination. GO:0019482 beta-alanine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019482 Wikipedia:Beta-alanine beta-alanine metabolism The chemical reactions and pathways involving beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins. GO:0019480 L-alanine oxidation to pyruvate via D-alanine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019480 MetaCyc:ALADEG-PWY The chemical reactions and pathways resulting in the breakdown of L-alanine to pyruvate, with D-alanine as an intermediate. CHEBI:67072 cannabinoid receptor agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67072 GO:0044401 multi-species biofilm formation in or on host organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044401 A process in which microorganisms of different species attach to and grow in or on a host species, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the microorganisms' growth rate and gene transcription. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0044402 obsolete competition with other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044402 competition with another organism|interspecies competition OBSOLETE. Any process in which an organism within a multispecies community gains an advantage in growth or survival over another organism of a different species in that community. GO:0044400 multi-species biofilm formation on inanimate substrate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044400 A process in which microorganisms of different species attach to and grow on an inanimate surface such as a rock or pipe and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription. CHEBI:67078 Delta(9)-tetrahydrocannabinolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67078 CHEBI:67079 anti-inflammatory agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67079 GO:0044409 entry into host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044409 entry into host cell via penetration peg|penetration into host via a specialized structure during symbiotic interaction|entry into cell of other organism involved in symbiotic interaction|invasion of host|penetration into host via a specialized structure|host cell invasion|entry into host through host barriers|entry into host cell|invasion into host|invasive growth|entry into other organism during symbiotic interaction|entry into other organism involved in symbiotic interaction|entry into host via enzymatic degradation of host cuticle|entry into host via enzymatic degradation of host anatomical structure|entry into cell of other organism during symbiotic interaction|other organism cell invasion|invasion of other organism|penetration into host|host penetration|invasion into other organism|entry into host via a specialized structure during symbiotic interaction|other organism invasion|host invasion Entry of a symbiont into the body, tissues, or cells of a host organism as part of the symbiont life cycle. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0044407 single-species biofilm formation in or on host organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044407 A process in which microorganisms of the same species attach to and grow in or on a host species, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the microorganisms' growth rate and gene transcription. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0044408 obsolete growth or development of symbiont on or near host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044408 growth or development of symbiont on or near host|growth or development of organism on or near host surface OBSOLETE. Any process in which the symbiont regulates the increase in its size or mass, or its progression from an initial condition to a later condition, within the cells or tissues of the host organism. GO:0044405 detection of host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044405 recognition of host The set of specific processes that allow an organism to detect the presence of its host via physical or chemical signals. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0044406 adhesion of symbiont to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044406 adhesion to other organism involved in symbiotic interaction|adhesion to other organism during symbiotic interaction|host adhesion|adhesion to host|adhesion to symbiont The attachment of a symbiont to its host via adhesion molecules, general stickiness etc., either directly or indirectly. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0044403 biological process involved in symbiotic interaction biolink:BiologicalProcess go-plus goslim_chembl|goslim_generic http://purl.obolibrary.org/obo/GO_0044403 symbiosis|symbiotic process|symbiotic interaction between host and organism|parasitism|symbiosis, encompassing mutualism through parasitism|symbiotic interaction between organisms|host-pathogen interaction|commensalism|symbiotic interaction between species|symbiotic interaction A process carried out by gene products in an organism that enable the organism to engage in a symbiotic relationship, a more or less intimate association, with another organism. The various forms of symbiosis include parasitism, in which the association is disadvantageous or destructive to one of the organisms; mutualism, in which the association is advantageous, or often necessary to one or both and not harmful to either; and commensalism, in which one member of the association benefits while the other is not affected. However, mutualism, parasitism, and commensalism are often not discrete categories of interactions and should rather be perceived as a continuum of interaction ranging from parasitism to mutualism. In fact, the direction of a symbiotic interaction can change during the lifetime of the symbionts due to developmental changes as well as changes in the biotic/abiotic environment in which the interaction occurs. Microscopic symbionts are often referred to as endosymbionts. GO:0044404 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044404 GO:0019478 D-amino acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019478 D-amino acid degradation|D-amino acid breakdown|D-amino acid catabolism The chemical reactions and pathways resulting in the breakdown of D-amino acids, the D-enantiomers of amino acids. GO:0019479 L-alanine oxidation to D-lactate and ammonia biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019479 MetaCyc:ALACAT2-PWY The chemical reactions and pathways resulting in the breakdown of L-alanine to D-lactate and ammonia. GO:0019476 D-lysine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019476 D-lysine catabolism|D-lysine degradation|D-lysine breakdown The chemical reactions and pathways resulting in the breakdown of D-lysine, the D-enantiomer of lysine; i.e. (2R)-2,6-diaminohexanoic acid. GO:0019477 L-lysine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019477 L-lysine catabolism|L-lysine degradation|L-lysine breakdown The chemical reactions and pathways resulting in the breakdown of L-lysine, the L-enantiomer of (S)-2,6-diaminohexanoic acid. CHEBI:67080 cannabinerolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67080 GO:0019474 L-lysine catabolic process to acetyl-CoA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019474 L-lysine degradation to acetyl-CoA|L-lysine breakdown to acetyl-CoA The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA. GO:0019475 L-lysine catabolic process to acetate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019475 MetaCyc:P163-PWY lysine fermentation|L-lysine breakdown to acetate|L-lysine degradation to acetate The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetate. GO:0019472 4-hydroxyproline biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019472 4-hydroxyproline biosynthesis|4-hydroxyproline anabolism|4-hydroxyproline synthesis|4-hydroxyproline formation The chemical reactions and pathways resulting in the formation of 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline. GO:0019473 L-lysine catabolic process to glutarate, by acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019473 MetaCyc:LYSDEGII-PWY L-lysine degradation to glutarate, by acetylation|L-lysine breakdown to glutarate, by acetylation The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including glutarate, by acetylation. GO:0019492 proline salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019492 proline cycling Any process which produces the amino acid proline from derivatives of it, without de novo synthesis. GO:0019493 arginine catabolic process to proline biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019493 MetaCyc:ARG-PRO-PWY arginine degradation to proline|arginine breakdown to proline The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including proline. GO:0019490 2-aminobenzenesulfonate desulfonation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019490 MetaCyc:2ASDEG-PWY 2-aminobenzenesulphonate desulphonation The removal of the sulfonate group from 2-aminobenzenesulfonate, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines. GO:0019491 ectoine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019491 MetaCyc:P101-PWY ectoine biosynthesis|ectoine anabolism|ectoine synthesis|ectoine formation The chemical reactions and pathways resulting in the formation of ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid), a tetrahydropyrimidine commonly synthesized by halophilic bacteria. CHEBI:67081 cannabigerolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67081 GO:0044412 obsolete growth or development of symbiont in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044412 growth or development of symbiont within host|growth or development of organism within host|growth or development of symbiont in host|invasive growth OBSOLETE. The increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down host tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0044413 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044413 GO:0044410 entry into host through natural portals biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044410 entry into other organism through natural portals involved in symbiotic interaction|entry into other organism through natural portals during symbiotic interaction Penetration by a symbiont into a host organism via naturally occurring openings in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0044411 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044411 CHEBI:67089 3,5,7-trioxododecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67089 GO:0044418 translocation of DNA into host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044418 translocation of DNA into other organism during symbiotic interaction|translocation of DNA into other organism involved in symbiotic interaction|transport of DNA into other organism during symbiotic interaction|transport of DNA into host The directed movement of DNA from an organism to a location inside its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0044419 biological process involved in interspecies interaction between organisms biolink:BiologicalProcess go-plus gocheck_do_not_annotate|goslim_pir|goslim_candida http://purl.obolibrary.org/obo/GO_0044419 interspecies interaction with other organisms|interspecies interaction between organisms|interaction with another species|interspecies interaction Any process evolved to enable an interaction with an organism of a different species. GO:0044416 induction by symbiont of host defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044416 induction by organism of defense response of other organism involved in symbiotic interaction|stimulation by symbiont of host defense response|up-regulation by symbiont of host defense response|activation of host defense response|upregulation by symbiont of host defense response|positive regulation by organism of defense response of other organism involved in symbiotic interaction|up regulation by symbiont of host defense response|positive regulation by symbiont of host defense response|activation by symbiont of host defense response The activation by an organism of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0044417 translocation of molecules into host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044417 transport of molecules into host|translocation of molecules into other organism during symbiotic interaction|translocation of molecules into other organism involved in symbiotic interaction|transport of molecules into other organism during symbiotic interaction The directed movement of a molecule(s) produced by an organism to a location inside its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0044414 suppression of host defenses by symbiont biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044414 inhibition by symbiont of host defense response|down regulation by organism of defense response of other organism during symbiotic interaction|negative regulation by organism of defense response of other organism involved in symbiotic interaction|suppression of defense response of other organism involved in symbiotic interaction|downregulation by organism of defense response of other organism during symbiotic interaction|suppression of host defense response|down regulation by symbiont of host defense response|down-regulation by organism of defense response of other organism during symbiotic interaction|inhibition by organism of defense response of other organism during symbiotic interaction|downregulation by symbiont of host defense response|negative regulation of host defenses|suppression of defenses of other organism involved in symbiotic interaction|negative regulation by organism of defense response of other organism during symbiotic interaction|down-regulation by symbiont of host defense response|negative regulation by symbiont of host defense response|suppression of defense response of other organism Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of host defense(s) by active mechanisms that normally result in the shutting down of a host pathway. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0044415 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044415 GO:0019489 methylgallate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019489 methylgallate metabolism The chemical reactions and pathways involving methylgallate, trihydroxymethylbenzoate, the anion of methylgallic acid. GO:0019487 anaerobic acetylene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019487 MetaCyc:P161-PWY anaerobic ethyne catabolism|anaerobic ethyne catabolic process|anaerobic acetylene degradation|anaerobic acetylene catabolism|anaerobic acetylene breakdown The chemical reactions and pathways involving acetylene, a colorless, volatile, explosive gas, that occur in the absence of oxygen. CHEBI:67090 N-acylsphinganine-1-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67090 GO:0019488 ribitol catabolic process to xylulose 5-phosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019488 MetaCyc:RIBITOLUTIL-PWY ribitol degradation to xylulose 5-phosphate|ribitol breakdown to xylulose 5-phosphate|ribitol utilization The chemical reactions and pathways resulting in the breakdown of ribitol to form xylulose 5-phosphate. Ribitol is initially converted to D-ribulose, which is phosphorylated to form ribulose 5-phosphate, which is then converted into xylulose 5-phosphate. GO:0019485 beta-alanine catabolic process to L-alanine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019485 beta-alanine breakdown to L-alanine|beta-alanine degradation to L-alanine The chemical reactions and pathways resulting in the breakdown of beta-alanine into other compounds, including L-alanine. GO:0019486 beta-alanine catabolic process to mevalonate semialdehyde, by transamination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019486 MetaCyc:BETA-ALA-DEGRADATION-I-PWY beta-alanine degradation to mevalonate semialdehyde, by transamination|beta-alanine breakdown to mevalonate semialdehyde, by transamination The chemical reactions and pathways resulting in the breakdown of beta-alanine into other compounds, including mevalonate semialdehyde, by transamination. GO:0019483 beta-alanine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019483 beta-alanine anabolism|beta-alanine biosynthesis|beta-alanine synthesis|beta-alanine formation The chemical reactions and pathways resulting in the formation of beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins. GO:0019484 beta-alanine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019484 beta-alanine catabolism|beta-alanine degradation|beta-alanine breakdown The chemical reactions and pathways resulting in the breakdown of beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins. CHEBI:57608 CDP-ribitol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57608 CHEBI:57609 (2S,6S)-2,6-diaminopimelic acid dizwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57609 CHEBI:57606 5-oxoprolinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57606 CHEBI:57607 oleandomycin 2'-O-phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57607 CHEBI:57604 3-phosphonato-D-glyceroyl phosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57604 CHEBI:57605 adenin-9-yl riburonosate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57605 CHEBI:33635 polycyclic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33635 CHEBI:33636 bicyclic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33636 CHEBI:33637 ortho-fused compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33637 CHEBI:33639 ortho- and peri-fused compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33639 CHEBI:57602 (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57602 CHEBI:57603 ethanolaminium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57603 CHEBI:57600 GTP(3-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_57600 CHEBI:57601 2-methylpropanaminium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57601 CHEBI:33646 alkadiene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33646 CHEBI:33647 alkatriene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33647 UBERON:0004495 skeletal muscle tissue of diaphragm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004495 A portion of skeletal muscle tissue that is part of a diaphragm [Automatically generated definition]. UBERON:0004493 cardiac muscle tissue of myocardium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004493 A portion of cardiac muscle tissue that is part of a myocardium [Automatically generated definition]. CHEBI:33641 olefin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33641 UBERON:0004491 cardiac muscle tissue of interatrial septum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004491 interatrial septum muscle|interatrial septum myocardium|interatrial septum heart muscle|interatrial septum cardiac muscle tissue A portion of cardiac muscle tissue that is part of a interatrial septum [Automatically generated definition]. CHEBI:33642 cyclic olefin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33642 UBERON:0004492 cardiac muscle tissue of cardiac septum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004492 cardiac septum cardiac muscle tissue|cardiac septum muscle|cardiac septum myocardium|cardiac septum heart muscle A portion of cardiac muscle tissue that is part of a cardiac septum [Automatically generated definition]. CHEBI:33643 cycloalkene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33643 CHEBI:33644 acetylenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33644 CHEBI:33645 acyclic olefin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33645 UBERON:0004490 cardiac muscle tissue of atrium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004490 atrial cardiac muscle tissue|atrial heart muscle|atrial myocardium|cardiac atrium muscle A portion of cardiac muscle tissue that is part of an atrium [Automatically generated definition]. CHEBI:18020 4-trimethylammoniobutanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18020 CHEBI:33613 2,2-bis(4-hydroxyphenyl)propan-1-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33613 CHEBI:33619 boron oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33619 UBERON:0004482 musculature of lower limb biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004482 musculature of free lower limb|muscle group of free lower limb|free lower limb musculature|set of muscles of free lower limb Any collection of muscles that is part of a hindlimb [Automatically generated definition]. UBERON:0004480 musculature of limb biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004480 limb musculature|set of muscles of limb|limb muscle system|muscle group of limb Any collection of muscles that is part of a limb [Automatically generated definition]. UBERON:0004481 musculature of upper limb biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004481 musculature of free upper limb|muscle group of free upper limb|free upper limb musculature|set of muscles of free upper limb Any collection of muscles that is part of a forelimb [Automatically generated definition]. CHEBI:33610 monoatomic boron biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33610 CHEBI:18019 L-lysine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18019 CHEBI:18016 3',4',5-trihydroxy-3,6,7-trimethoxyflavone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18016 CHEBI:18014 CMP-3-deoxy-alpha-D-manno-octulosonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18014 CHEBI:18015 oxidized Latia luciferin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18015 UBERON:0004488 musculature of pes biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004488 musculature of foot|foot musculature|set of muscles of foot|muscle group of foot Any collection of muscles that is part of a foot [Automatically generated definition]. CHEBI:18012 fumaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18012 UBERON:0004489 musculature of manus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004489 musculature of hand|hand musculature|set of muscles of hand|muscle group of hand Any collection of muscles that is part of a manus [Automatically generated definition]. CHEBI:18013 4-O-feruloyl-D-quinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18013 CHEBI:18010 3',4',5-trihydroxy-3,7-dimethoxyflavone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18010 CHEBI:18011 androstane-3alpha,17beta-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18011 UBERON:0004487 musculature of forelimb zeugopod biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004487 musculature of forearm|muscle group of forearm|set of muscles of forearm Any collection of muscles that is part of a lower arm [Automatically generated definition]. CHEBI:33624 bromophenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33624 CHEBI:33625 dibromophenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33625 CHEBI:33628 elemental aluminium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33628 UBERON:0004473 musculature of face biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004473 musculi faciei|entire facial musculature|set of muscles of face|muscle group of face|set of facial muscles|facial muscles Any collection of muscles that is part of a face. UBERON:0004474 musculature of arm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004474 muscle group of arm|arm musculature|set of muscles of arm|arm muscle system Any collection of muscles that is part of an arm [Automatically generated definition]. UBERON:0004471 musculature of pectoral girdle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004471 muscle group of pectoral girdle|pectoral girdle musculature|pectoral girdle muscles|set of muscles of pectoral girdle A subdivision of the musculature of the body in the pectoral girdle region. Includes pectoral and shoulder muscles. CHEBI:18009 NADP(+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18009 CHEBI:33620 aluminium molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33620 UBERON:0004470 musculature of pelvic girdle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004470 set of muscles of pelvis|muscle group of pelvis|muscular system of pelvis|muscle group of pelvic girdle|pelvic girdle musculature|pelvic girdle muscles|set of muscles of pelvic girdle|pelvic girdle muscle system Any collection of muscles that is part of a pelvic girdle [Automatically generated definition]. CHEBI:18007 3-[hydroxy(oxido)phosphoranyl]pyruvic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18007 CHEBI:18005 keto-phenylpyruvate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18005 UBERON:0004479 musculature of trunk biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004479 muscle group of trunk|muscular system of trunk|set of muscles of trunk Any collection of muscles that is part of a trunk [Automatically generated definition]. CHEBI:18003 2-hydroxy-3-(3-oxoprop-1-enyl)but-2-enedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18003 CHEBI:18004 D-hamamelose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18004 CHEBI:18002 (-)-secologanin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18002 UBERON:0004478 musculature of larynx biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004478 set of muscles of larynx|muscle group of larynx|laryngeal muscles set|laryngeal muscles|set of laryngeal muscles The collection of muscles that are part of the larynx. UBERON:0004475 musculature of hip biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004475 muscle group of hip|hip musculature|set of muscles of hip The collection of muscles that form attachments to the hip skeleton. UBERON:0004476 musculature of shoulder biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004476 set of muscles of shoulder|muscle group of shoulder The collection of muscles that form attachments to the shoulder skeleton. CHEBI:18000 aralkylamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18000 CHEBI:82608 alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82608 CHEBI:82609 alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82609 CHEBI:82606 1,2-dibutyryl-sn-glycero-3-phospho-(1'D-myo-inositol)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82606 CHEBI:82607 alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-beta-D-GalNAc-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82607 CHEBI:82605 1,2-dibutyryl-sn-glycero-3-phospho-(1'D-myo-inositol-5'-phosphate)(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82605 CHEBI:82611 2-O,3-dimethylflaviolin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82611 CHEBI:82612 S-methyl-L-cysteine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82612 CHEBI:82610 6-linalyl-2-O,3-dimethylflaviolin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82610 CHEBI:33608 hydrogen molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33608 CHEBI:33609 elemental boron biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33609 CHEBI:82628 11(R)-HPETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82628 CHEBI:82629 prostaglandin G2(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82629 CHEBI:82626 15(R)-HPETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82626 CHEBI:82627 15(R)-HPETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82627 CHEBI:82620 L-tyrosine-O-phosphate(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82620 CHEBI:82639 alpha-N-acetylneuraminosyl-(2->3)-[beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82639 CHEBI:82637 alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)-[alpha-N-acetylneuraminosyl-(2->3)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82637 CHEBI:82635 4-nitrophenyl acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82635 CHEBI:82633 N-acetyl-alpha-neuraminosyl-(2->3)-D-galactosylceramide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82633 CHEBI:67008 kynureninate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67008 CHEBI:82631 N-threonyl-glycosylphosphatidylinositolethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82631 CHEBI:67001 hypusinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67001 CHEBI:82632 phytochrome chromophore biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82632 CHEBI:67009 S-adenosyl-L-homocysteinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67009 GO:0044382 CLRC complex localization to heterochromatin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044382 CLRC ubiquitin ligase complex localization to heterochromatin|CLRC ubiquitin ligase complex localisation to heterochromatin The process by which a CLRC complex is transported to, or maintained in, heterochromatin. CLRC complex is an active cullin-dependent E3 ubiquitin ligase complex essential for heterochromatin assembly by RNAi and histone H3K9 methylation. CHEBI:18085 glycosaminoglycan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18085 GO:0044383 host chromosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044383 A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information, occurring within a host cell. CHEBI:18086 indol-3-ylacetaldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18086 GO:0044380 protein localization to cytoskeleton biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044380 protein localisation to cytoskeleton A process in which a protein is transported to, or maintained in, a location within the cytoskeleton. CHEBI:18083 1-methyladenine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18083 GO:0044381 glucose import in response to insulin stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044381 cellular glucose import in response to insulin stimulus The directed movement of the hexose monosaccharide glucose into a cell as a result of an insulin stimulus. CHEBI:18084 testololactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18084 CHEBI:18081 3-hexaprenyl-4,5-dihydroxybenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18081 CHEBI:18082 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18082 CHEBI:18080 5-oxo-2,5-dihydro-2-furylacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18080 GO:0044388 small protein activating enzyme binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044388 Interacting selectively and non-covalently with a small protein activating enzyme, such as ubiquitin-activating enzyme. GO:0044389 ubiquitin-like protein ligase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044389 small conjugating protein ligase binding|E3 protein ligase binding Interacting selectively and non-covalently with a ubiquitin-like protein ligase, such as ubiquitin-ligase. GO:0044386 integral to host endoplasmic reticulum membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044386 Penetrating at least one phospholipid bilayer of an endoplasmic reticulum membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. Occurring in a host cell. GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044387 The stopping, prevention, or reduction in frequency, rate or extent of protein kinase activity as a result of regulating the phosphorylation status of that protein kinase. GO:0044384 host outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044384 host cell outer membrane The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites, occurring in a host cell. GO:0044385 integral to membrane of host cell biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044385 Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane. Occurring in a host cell. CHEBI:57682 coformycin(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57682 CHEBI:57683 dolichyl phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57683 CHEBI:57680 sinapoyltartronate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57680 CHEBI:57681 cis-2-chloro-4-carboxylatomethylenebut-2-en-1,4-olide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57681 CHEBI:57688 S-formylglutathionate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57688 CHEBI:57689 2,2-dialkylglycine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57689 CHEBI:18078 2-dehydro-3-deoxy-L-rhamnonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18078 CHEBI:57684 beta-D-glucose 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57684 CHEBI:57685 sn-glycerol 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57685 CHEBI:18077 dTTP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18077 GO:0044393 microspike biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044393 A dynamic, actin-rich projection extending from the surface of a migrating animal cell. GO:0044394 protein malonylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044394 The modification of a protein amino acid by the addition of a malonyl (CO-CH2-CO) group. CHEBI:18075 dTDP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18075 GO:0044391 ribosomal subunit biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044391 Either of the two subunits of a ribosome: the ribosomal large subunit or the ribosomal small subunit. CHEBI:18072 5-hydroxyisouric acid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18072 GO:0044392 peptidyl-lysine malonylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044392 RESID:AA0568 lysine malonylation The addition of a malonyl group (CO-CH2-CO) to peptidyl-lysine to form N6-malonyl-L-lysine. CHEBI:18073 xanthoaphin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18073 CHEBI:18070 cytochrome c biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18070 UBERON:0004409 distal epiphysis of phalanx of manus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004409 head of phalanx of finger|distal epiphysis of phalanx of hand|distal epiphysis of phalanx of finger|distal end of phalanx of hand|ungual tuberosity of distal phalanx of finger|head of phalanx of hand A distal epiphysis that is part of a phalanx of manus [Automatically generated definition]. GO:0044390 ubiquitin-like protein conjugating enzyme binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044390 E2 protein ligase binding|small protein conjugating enzyme binding Interacting selectively and non-covalently with a ubiquitin-like protein conjugating enzyme such as ubiquitin conjugating enzyme. CHEBI:18071 (methylthio)acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18071 UBERON:0004406 distal epiphysis of femur biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004406 distal femoral epiphysis|distal head of femur A distal epiphysis that is part of a femur [Automatically generated definition]. GO:0044399 multi-species biofilm formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044399 A process in which planktonically growing microorganisms of different species grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription. GO:0044397 obsolete actin cortical patch internalization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044397 OBSOLETE. A process of actin cortical patch localization in which the patch moves from the cell surface to the inside of the cell. CHEBI:43034 7,8-didemethyl-8-hydroxy-5-deazariboflavin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_43034 GO:0044398 envenomation resulting in induction of edema in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044398 envenomation resulting in induction of oedema in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the swelling of soft tissues of the bitten organism as a result of excess water accumulation. CHEBI:43035 (R)-hydratropic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_43035 GO:0044395 protein targeting to vacuolar membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044395 The process of directing proteins towards the vacuolar membrane; usually uses signals contained within the protein. GO:0044396 actin cortical patch organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044396 actin cortical patch organisation A process that is carried out at the cellular level and results in the assembly, arrangement of constituent parts, or disassembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane in cells, at sites of endocytosis. CHEBI:57671 1-ammonio-1-deoxy-scyllo-inositol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57671 CHEBI:57672 7-O-acetylsalutaridinol(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57672 CHEBI:57670 N-acylglycinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57670 CHEBI:1015 2-aminobenzenesulfonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_1015 UBERON:0004415 proximal epiphysis of metatarsal bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004415 basis ossis metatarsi|base of metatarsal bone|proximal end of metatarsal bone|upper end of metatarsal bone A proximal epiphysis that is part of a metatarsal bone [Automatically generated definition]. CHEBI:57679 hypotaurocyamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57679 UBERON:0004416 proximal epiphysis of metacarpal bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004416 proximal end of metacarpal bone|metacarpal bone base|upper end of metacarpal bone|basis ossis metacarpi|base of metacarpal bone A proximal epiphysis that is part of a metacarpal bone [Automatically generated definition]. CHEBI:57677 sn-3-O-(geranylgeranyl)glycerol 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57677 UBERON:0004414 proximal epiphysis of phalanx of manus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004414 basal epiphysis of phalanx of finger|basis phalangis manus|base of phalanx of finger|proximal epiphysis of phalanx of hand|proximal epiphysis of phalanx of finger A proximal epiphysis that is part of a phalanx of manus [Automatically generated definition]. CHEBI:57678 3-mercaptopyruvate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57678 UBERON:0004411 proximal epiphysis of humerus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004411 head of the humerus|proximal end of humerus|proximal humeral epiphysis|upper extremity of humerus|upper end of humerus|humeral head|proximal humerus The upper extremity of the humerus (proximal humerus) consists of a large rounded head joined to the body by a constricted portion called the neck, and two eminences, the greater and lesser tubercles. CHEBI:18067 phylloquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18067 UBERON:0004412 proximal epiphysis of femur biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004412 proximal femoral epiphysis|capital femoral epiphysis A proximal epiphysis that is part of a femur [Automatically generated definition]. CHEBI:57676 questin-2-olate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57676 CHEBI:57673 2'-deoxyguanosine 5'-monophosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57673 CHEBI:18065 deacetylcephalosporin C biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18065 UBERON:0004410 distal epiphysis of fibula biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004410 lower end of fibula|distal end of fibula A distal epiphysis that is part of a fibula [Automatically generated definition]. CHEBI:18066 UDP-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18066 CHEBI:57674 N-acylsphingosine 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57674 CHEBI:33693 oxygen hydride biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33693 CHEBI:57660 myo-inositol 1,3,4,6-tetrakisphosphate(8-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57660 CHEBI:57661 O-succinyl-L-homoserinate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57661 CHEBI:33694 biomacromolecule biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33694 CHEBI:33695 information biomacromolecule biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33695 CHEBI:33696 nucleic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33696 CHEBI:140810 beta-D-glucosamine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140810 CHEBI:33697 ribonucleic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33697 CHEBI:43029 L-erythro-7,8-dihydrobiopterin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_43029 CHEBI:33699 messenger RNA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33699 UBERON:0004404 distal epiphysis of humerus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004404 lower end of humerus|distal end of humerus A distal epiphysis that is part of a humerus [Automatically generated definition]. CHEBI:57668 D-ornithinium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57668 UBERON:0004405 distal epiphysis of tibia biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004405 lower end of tibia|distal end of tibia A distal epiphysis that is part of a tibia [Automatically generated definition]. CHEBI:57666 N-acyl-D-mannosamine 6-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57666 UBERON:0004402 bone tissue of proximal epiphysis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004402 A portion of bone tissue that is part of a proximal epiphysis [Automatically generated definition]. CHEBI:57667 dADP(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57667 CHEBI:57664 6-hydroxynicotinate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57664 UBERON:0004400 bone tissue of epiphysis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004400 A portion of bone tissue that is part of a epiphysis [Automatically generated definition]. UBERON:0004401 bone tissue of distal epiphysis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004401 A portion of bone tissue that is part of a distal epiphysis [Automatically generated definition]. CHEBI:57665 neryl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57665 CHEBI:57662 S-carboxylatomethyl-L-cysteine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57662 CHEBI:18098 CMP-N-glycoloyl-beta-neuraminic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18098 CHEBI:140817 alpha-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140817 CHEBI:57663 2-caffeoylisocitrate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57663 CHEBI:33692 hydrides biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33692 CHEBI:18099 cyclohexanol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18099 CHEBI:18094 1,4-dihydroxy-2-naphthoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18094 CHEBI:18095 trans-4-hydroxy-L-proline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18095 CHEBI:18092 8'-apo-beta-carotenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18092 CHEBI:18093 17,21-dihydroxy-5beta-pregnane-3,11,20-trione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18093 CHEBI:18090 3-aminopropanal biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18090 CHEBI:18091 asparagusic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18091 CHEBI:57657 11-O-demethyl-17-O-deacetylvindolinium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57657 CHEBI:57658 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57658 CHEBI:57655 3-dehydro-L-gulonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57655 CHEBI:57656 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57656 CHEBI:18089 N-benzoylglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18089 CHEBI:57653 2-deoxy-D-gluconate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57653 CHEBI:57654 undecaprenyl phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57654 CHEBI:57651 2-deoxy-D-ribose 5-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57651 CHEBI:18087 myo-inositol polyphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18087 CHEBI:18088 formononetin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18088 CHEBI:57652 chondroitin D-glucuronate anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57652 CHEBI:18041 (S)-lactaldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18041 CHEBI:18042 (S)-2,3-dihydrodipicolinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18042 OBO:cl#has_not_completed has_not_completed biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/cl#has_not_completed has_not_completed CHEBI:18040 erythro-5-hydroxy-L-lysine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18040 CHEBI:57649 dTDP-4-dehydro-6-deoxy-alpha-D-glucose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57649 UBERON:0004462 musculature of body wall biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004462 body wall musculature|body wall muscles Any collection of muscles that is part of a body wall [Automatically generated definition]. CHEBI:33671 heteropolycyclic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33671 UBERON:0004463 musculature of hindlimb stylopod biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004463 muscle group of thigh|thigh musculature|set of muscles of thigh|musculature of thigh Any collection of muscles that is part of a hindlimb stylopod (upper leg / thigh)[Automatically generated definition]. CHEBI:33672 heterobicyclic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33672 CHEBI:33673 zinc group molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33673 UBERON:0004461 skeletal musculature of head biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004461 muscle group of head|muscles of head|head musculature|musculi capitis|set of muscles of head Any collection of skeletal muscles that is part of a head [Automatically generated definition]. CHEBI:33674 s-block molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33674 CHEBI:33675 p-block molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33675 CHEBI:33676 d-block molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33676 CHEBI:57646 N-acetyl-beta-D-galactosaminyl-(1->4)-alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57646 CHEBI:18038 GDP-L-galactose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18038 CHEBI:57647 3-(4-hydroxy-3,5-diiodophenyl)lactate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57647 CHEBI:18039 N-phospho-L-lombricine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18039 CHEBI:18036 triphosphate(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18036 UBERON:0004468 set of muscles of vertebral column biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004468 muscle group of vertebral column CHEBI:57644 chlorogenate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57644 UBERON:0004469 musculature of back biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004469 muscle group of back|musculi dorsi|muscles of back|set of muscles of back Any collection of muscles that is part of a back [Automatically generated definition]. CHEBI:18037 3-oxolauric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18037 CHEBI:18034 4-fumarylacetoacetate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18034 UBERON:0004466 musculature of leg biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004466 leg muscle system Any collection of muscles that is part of a lower leg or upper leg [Automatically generated definition]. CHEBI:57642 glycerone phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57642 CHEBI:18035 diglyceride biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18035 CHEBI:57643 1,2-diacyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57643 UBERON:0004467 musculature of pharynx biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004467 set of muscles of pharynx|pharyngeal musculature the collection of muscles that acts on the pharynx. CHEBI:57640 1,6-dihydroxy-2-methylcyclohexa-2,4-diene-1-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57640 UBERON:0004464 musculature of thorax biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004464 muscles of thorax|thoracic musculature|set of muscles of thorax|musculi thoracis|muscle group of thorax Any collection of muscles that is part of a thorax [Automatically generated definition]. CHEBI:18032 4-amino-2-methyl-5-phosphooxymethylpyrimidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18032 UBERON:0004465 musculature of neck biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004465 set of muscles of neck|muscle group of neck|musculi colli|musculi cervicis|cervical muscles|muscles of neck|neck musculature Any collection of muscles that is part of a neck [Automatically generated definition]. CHEBI:18033 2-formylphenylformamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18033 CHEBI:57641 2,4-dichloro-5-oxo-2,5-dihydro-2-furylacetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57641 CHEBI:33670 heteromonocyclic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33670 CHEBI:18030 quercetin 3,4'-bissulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18030 CHEBI:57639 4-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57639 CHEBI:57637 2-methylene-3-methylsuccinate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57637 CHEBI:57638 GDP-6-deoxy-alpha-D-talose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57638 UBERON:0004451 trunk or cervical vertebra biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004451 presacral vertebra A vertebra in the trunk or cervical region. Includes all cervical, thoracic and lumbar vertebrae, but excludes caudal vertebra. UBERON:0004452 carpal region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004452 wrist|wrist region|hand mesopodium|carpal limb segment|carpus of fore-paw|articulatio radiocarpea|carpal segment|manus mesopodium|regio carpalis|carpus|fore basipodium|fore mesopodium A mesopodium that is part of a manus. Includes as parts the carpal skeleton and associated tissues[cjm]. The anatomical region surrounding the carpus including the distal parts of the bones of the forearm and the proximal parts of the metacarpus or five metacarpal bones and the series of joints between these bones, thus referred to as wrist joints. This region also includes the carpal tunnel, the anatomical snuff box, the flexor retinaculum, and the extensor retinaculum[WP,unvetted] CHEBI:18029 dihydromacarpine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18029 CHEBI:18027 (-)-aristolochene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18027 CHEBI:57635 UDP-alpha-D-galacturonate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57635 CHEBI:57633 (S)-3-(indol-3-yl)-2-oxobutyrate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57633 CHEBI:18025 2-hydroxypropyl dihydrogen phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18025 CHEBI:18026 2,3-dihydroxybenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18026 CHEBI:57634 beta-D-fructofuranose 6-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57634 UBERON:0004455 neurula embryo biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004455 neurula An embryo at the neurula stage. CHEBI:18023 sirohydrochlorin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18023 CHEBI:57631 dTDP-L-dihydrostreptose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57631 UBERON:0004456 entire sense organ system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004456 sense organ system Sum of all sensory systems in an organism. CHEBI:18024 D-galacturonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18024 CHEBI:57632 UDP-alpha-D-xylose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57632 CHEBI:18021 phosphoenolpyruvate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18021 UBERON:0004453 metacarpus region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004453 forelimb cannon region|metacarpal part of manus|metacarpal region|forelimb equine cannon region|metacarpal part of hand|metacarpus|distal segment of hand proper A metapodium region that is part of a manus. UBERON:0004454 tarsal region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004454 tarsal limb segment|hock|articulatio talocruralis|ankle region|ankle|hind basipodium|hind mesopodium mesopodial segment of the pes, including the tarsal skeleton and associated tissues. CHEBI:18022 thiocyanate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18022 CHEBI:57630 gamma-amino-beta-hydroxybutyric acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57630 CHEBI:18063 2-O-acyl-3-O-beta-D-galactosyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18063 CHEBI:18064 3-hydroxyisobutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18064 CHEBI:18062 4-guanidinobutanamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18062 CHEBI:57628 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57628 CHEBI:57629 D-glucopyranose 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57629 CHEBI:18060 1-haloalkane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18060 CHEBI:57626 limonin 17-beta-D-glucoside(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57626 CHEBI:57627 1D-myo-inositol 1,4,5,6-tetrakisphosphate(8-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57627 CHEBI:33658 arene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33658 CHEBI:33659 organic aromatic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33659 CHEBI:33650 acyclic acetylene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33650 PATO:0002124 laminar biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PATO_0002124 CHEBI:33653 aliphatic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33653 CHEBI:33654 alicyclic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33654 CHEBI:33655 aromatic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33655 UBERON:0004448 distal epiphysis of phalanx biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004448 head of phalanx A distal epiphysis that is part of a phalanx [Automatically generated definition]. UBERON:0004449 cerebral artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004449 One of three main pairs of arteries and their branches, which irrigate the cerebrum of the brain. UBERON:0004446 epiphysis of phalanx biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004446 An epiphysis that is part of a phalanx [Automatically generated definition]. CHEBI:18058 oxamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18058 CHEBI:57623 prenyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57623 CHEBI:18059 lipid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18059 UBERON:0004447 proximal epiphysis of phalanx biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004447 A proximal epiphysis that is part of a phalanx [Automatically generated definition]. CHEBI:57620 poly(ribitol phosphate) polyanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_57620 CHEBI:18056 N-acetyl-alpha-D-galactosaminyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18056 CHEBI:57621 2-benzylsuccinate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57621 CHEBI:18057 vellosimine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18057 CHEBI:18054 diphthine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18054 CHEBI:18052 loganate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18052 CHEBI:18053 1-aminocyclopropanecarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18053 CHEBI:57619 CDP-abequose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57619 CHEBI:18050 L-glutamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18050 CHEBI:18051 L-aspartic 4-semialdehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18051 CHEBI:57617 alpha-D-galactosyl undecaprenyl diphosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57617 CHEBI:57618 FMNH2(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57618 CHEBI:57616 L-methioninium residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57616 CHEBI:33661 monocyclic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33661 CHEBI:33662 annulene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33662 CHEBI:33663 cyclic hydrocarbon biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33663 CHEBI:33664 monocyclic hydrocarbon biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33664 CHEBI:33666 polycyclic hydrocarbon biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33666 CHEBI:18049 piperidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18049 CHEBI:57613 phosphatidylethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57613 CHEBI:57614 ITP(3-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_57614 CHEBI:18047 dihydrolipoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18047 CHEBI:57612 phosphonatoguanidiniumylacetate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57612 CHEBI:18048 DIMBOA biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18048 CHEBI:57610 N(alpha),N(alpha)-dimethyl-L-histidine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57610 CHEBI:18046 4-carboxy-2-hydroxy-cis,cis-muconate 6-semialdehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18046 CHEBI:18043 ricinine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18043 CHEBI:18044 dialkyl ketone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18044 GO:0019580 galactarate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019580 D-galactarate metabolic process|D-galactarate metabolism|mucic acid metabolic process|galactarate metabolism|mucic acid metabolism The chemical reactions and pathways involving galactarate, an anion of galactaric acid, the meso-aldaric acid derived from both D- and L-galactose. GO:0019581 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019581 GO:0044544 envenomation resulting in plasminogen activation in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044544 The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with the activation of plasminogen into plasmin in the bitten organism. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide. GO:0044545 NSL complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044545 non-specific lethal complex A histone acetyltransferase complex that catalyzes the acetylation of a histone H4 lysine residues at several positions. In human, it contains the catalytic subunit MOF, NSL1/KIAA1267, NSL2/KANSL2, NSL3/KANSL3, MCRS1, PHF20, OGT1, WDR5 and HCF1. GO:0044542 plasminogen activation in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044542 The chemical reactions and pathways performed by an organism resulting in the processing of inactive plasminogen to active plasmin in another organism. GO:0044543 envenomation resulting in zymogen activation in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044543 The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with the proteolytic processing of an inactive enzyme to an active form. GO:0044540 L-cystine L-cysteine-lyase (deaminating) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044540 RHEA:24927|KEGG_REACTION:R02408|EC:4.4.1.1 Catalysis of the reaction: L-cystine + H2O <=> pyruvate + NH3 + thiocysteine. Thiocysteine is also known as cysteine persulfide. GO:0044541 zymogen activation in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044541 The chemical reactions and pathways performed by an organism resulting in the proteolytic processing of an inactive enzyme to an active form in another organism. GO:0044548 S100 protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044548 S100 alpha binding|S100 binding|S100 beta binding Interacting selectively and non-covalently with a S100 protein. S100 is a small calcium and zinc binding protein produced in astrocytes that is implicated in Alzheimer's disease, Down Syndrome and ALS. GO:0044549 GTP cyclohydrolase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044549 GTP cyclohydrolase I binding Interacting selectively and non-covalently with a GTP cyclohydrolase. GO:0044546 NLRP3 inflammasome complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044546 NALP3 inflammasome complex assembly|NLRP3 inflammasome activation The aggregation, arrangement and bonding together of a set of components to form the NLRP3 inflammasome complex, occurring at the level of an individual cell. GO:0019579 aldaric acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019579 aldaric acid degradation|aldaric acid breakdown|aldaric acid catabolism The chemical reactions and pathways resulting in the breakdown of aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group. GO:0044547 DNA topoisomerase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044547 DNA topoisomerase I binding Interacting selectively and non-covalently with a DNA topoisomerase. GO:0019577 aldaric acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019577 aldaric acid metabolism The chemical reactions and pathways involving aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group. GO:0019578 aldaric acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019578 aldaric acid synthesis|aldaric acid formation|aldaric acid biosynthesis|aldaric acid anabolism The chemical reactions and pathways resulting in the formation of aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group. PR:000018271 interferon gamma proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000018271 IFNG/ClvPrd An interferon gamma that has been processed by proteolytic cleavage. GO:0019575 obsolete sucrose catabolic process, using beta-fructofuranosidase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019575 MetaCyc:SUCUTIL-PWY sucrose catabolism, using beta-fructofuranosidase|sucrose catabolic process, using beta-fructofuranosidase|sucrose breakdown, using beta-fructofuranosidase|sucrose degradation, using beta-fructofuranosidase OBSOLETE. The chemical reactions and pathways resulting in the breakdown of sucrose, catalyzed by the enzyme beta-fructofuranosidase (EC:3.2.1.26). GO:0019576 aerobic fructose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019576 aerobic fructose breakdown|aerobic fructose catabolism|aerobic fructose degradation The chemical reactions and pathways resulting in the breakdown of fructose that occurs in the presence of oxygen. GO:0019573 D-arabinose catabolic process to xylulose 5-phosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019573 MetaCyc:DARABCAT-PWY D-arabinose degradation to xylulose 5-phosphate|D-arabinose breakdown to xylulose 5-phosphate The chemical reactions and pathways resulting in the breakdown of D-arabinose to form xylulose 5-phosphate. D-arabinose is converted into D-ribulose, which is phosphorylated to ribulose-5-phosphate, which is isomerized to give D-xylulose-5-phosphate. GO:0019574 sucrose catabolic process via 3'-ketosucrose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019574 MetaCyc:SUCROSEUTIL2-PWY sucrose breakdown, using glucoside 3-dehydrogenase|sucrose degradation, using glucoside 3-dehydrogenase|sucrose catabolism, using glucoside 3-dehydrogenase|sucrose catabolic process to D-glucose|sucrose catabolic process, using glucoside 3-dehydrogenase The chemical reactions and pathways resulting in the breakdown of sucrose, which proceeds via the conversion of sucrose to 3'-ketosucrose. 3'-ketosucrose is hydrolyzed to 3-ketoglucose and fructose, and the 3-ketoglucose is then be converted to glucose. GO:0019571 D-arabinose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019571 D-arabinose degradation|D-arabinose breakdown|D-arabinose catabolism The chemical reactions and pathways resulting in the breakdown of D-arabinose, the D-enantiomer of arabino-pentose. GO:0019572 L-arabinose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019572 L-arabinose breakdown|L-arabinose catabolism|L-arabinose degradation The chemical reactions and pathways resulting in the breakdown of L-arabinose, the L-enantiomer of arabino-pentose. GO:0019591 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019591 GO:0019592 mannitol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019592 MetaCyc:PWY-3861|MetaCyc:MANNIDEG-PWY mannitol degradation|mannitol breakdown|mannitol catabolism The chemical reactions and pathways resulting in the breakdown of mannitol, the alditol derived from D-mannose by reduction of the aldehyde group. GO:0019590 L-arabitol catabolic process to xylulose 5-phosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019590 MetaCyc:LARABITOLUTIL-PWY L-arabitol breakdown to xylulose 5-phosphate|L-arabitol and xylitol degradation|L-arabitol utilization|L-arabitol degradation to xylulose 5-phosphate The chemical reactions and pathways resulting in the breakdown of L-arabitol to form xylulose 5-phosphate. L-arabitol is converted into L-xylulose, which is then phosphorylated to L-xylulose-5-phosphate. This is converted to D-xylulose-5-phosphate via the intermediate L-ribulose-5-phosphate. GO:0044555 negative regulation of heart rate in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044555 Any process that stops, prevents or reduces the frequency of heart contraction of another organism. GO:0044556 envenomation resulting in negative regulation of heart rate of other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044556 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the negative regulation of the heart rate of the bitten/stung organism. GO:0044553 modulation of biological quality in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044553 regulation of biological quality in other organism Any process that modulates the frequency, rate or extent of a biological quality in another organism. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc. GO:0044554 modulation of heart rate in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044554 regulation of heart rate in other organism Any process that modulates the frequency or rate of heart contraction of another organism. GO:0044551 envenomation resulting in vasodilation in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044551 envenomation resulting in regulation of vasodilation in other organism|envenomation resulting in modulation of vasodilation in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with resultant vasodilation of blood vessels, usually causing a reduction in blood pressure, in the bitten/stung organism. GO:0044552 vasodilation in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044552 modulation of vasodilation in other organism|regulation of vasodilation in other organism A process by which an organism causes vasodilation of blood vessels, usually causing a reduction in blood pressure, in another organism. GO:0044550 secondary metabolite biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044550 secondary metabolite biosynthesis The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. GO:0044559 envenomation resulting in modulation of voltage-gated potassium channel activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044559 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of a voltage-gated potassium channel in the bitten/stung organism. GO:0044557 relaxation of smooth muscle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044557 smooth muscle relaxation A process in which the extent of smooth muscle contraction is reduced. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length. GO:0044558 uterine smooth muscle relaxation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044558 smooth muscle relaxation of the uterus A process in which the extent of smooth muscle contraction is reduced in the uterus. GO:0019588 anaerobic glycerol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019588 glycerol fermentation The anaerobic chemical reactions and pathways resulting in the breakdown of glycerol, yielding energy in the form of ATP. GO:0019589 anaerobic glycerol catabolic process to propane-1,3-diol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019589 MetaCyc:GOLPDLCAT-PWY glycerol fermentation to 1,3-propanediol|glycerol fermentation to propane-1,3-diol The anaerobic chemical reactions and pathways resulting in the breakdown of glycerol into propane-1,3-diol and water. PR:000018263 amino acid chain biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000018263 peptide|polypeptide An organic amino compound that is a polymer of amino acid chain components (unmodified amino-acid residues and/or modified amino-acid residues) linked by peptide bonds or derivatives of such bonds. GO:0019586 galacturonate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019586 galacturonate metabolism The chemical reactions and pathways involving galacturonate, the anion of galacturonic acid, the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group. GO:0019587 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019587 GO:0019584 galactonate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019584 MetaCyc:GALACTCAT-PWY galactonate degradation|galactonate breakdown|galactonate catabolism The chemical reactions and pathways resulting in the breakdown of galactonate, the anion of galactonic acid. GO:0019585 glucuronate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019585 Wikipedia:Glucuronic_acid glucuronate metabolism The chemical reactions and pathways involving glucuronate, any salt or ester of glucuronic acid, the uronic acid formally derived from glucose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group. PR:000018264 proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000018264 peptide|ClvPrd|polypeptide A protein that is produced as the result of proteolytic processing of a longer protein. GO:0019582 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019582 GO:0019583 galactonate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019583 galactonate metabolism The chemical reactions and pathways involving galactonate, the anion of galactonic acid, an organic acid derived from the sugar galactose. GO:0044566 chondrocyte activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044566 A change in the morphology or behavior of a chondrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. A chondrocyte is a polymorphic cell that forms cartilage. GO:0044567 primary cell wall cellulose synthase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044567 primary cell wall CESA complex|primary cell-wall cellulose synthase complex A large, multimeric protein complex which catalyzes the biosynthesis of cellulose for the plant primary cell wall. In Arabidopsis, contains the essential component proteins CESA1 and -3, and a CESA6-related protein. GO:0044564 envenomation resulting in occlusion of the pore of voltage-gated potassium channel in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044564 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant blocking of a voltage-gated potassium channel, inhibiting the pore's activity, in the bitten/stung organism. GO:0044565 dendritic cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044565 The expansion of a dendritic cell population by cell division. A dendritic cell is a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. GO:0044562 envenomation resulting in negative regulation of voltage-gated potassium channel activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044562 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant negative regulation of the activity of a voltage-gated potassium channel in the bitten/stung organism. GO:0044563 envenomation resulting in slowing of activation kinetics of voltage-gated potassium channel in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044563 voltage-dependence of activation shift (to the left) A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant slowing of the activation kinetics of the activity of a voltage-gated potassium channel in the bitten/stung organism. GO:0044560 envenomation resulting in modulation of ion channel activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044560 envenomation resulting in regulation of ion channel activity in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of an ion channel in the bitten organism. GO:0044561 modulation of ion channel activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044561 regulation of ion channel activity in other organism Any process in which an organism effects a change in the frequency, rate or extent of the activity of an ion channel in another organism. GO:0019559 histidine catabolic process to imidazol-5-yl-lactate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019559 MetaCyc:HISTDEG-PWY histidine breakdown to imidazol-5-yl-lactate|histidine degradation to imidazol-5-yl-lactate The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including imidazol-5-yl-lactate. GO:0044568 secondary cell wall cellulose synthase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044568 secondary cell wall CesA complex|secondary cell wall CESA complex|secondary cell-wall cellulose synthase complex A large, multimeric protein complex which catalyzes the biosynthesis of cellulose for the plant secondary cell wall. In Arabidopsis, contains the essential component proteins CESA8, CESA7, and CESA4. GO:0019557 histidine catabolic process to glutamate and formate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019557 histidine breakdown to glutamate and formate|histidine degradation to glutamate and formate The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including glutamate and formate. GO:0019558 histidine catabolic process to 2-oxoglutarate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019558 histidine catabolic process to alpha-oxoglutarate|histidine catabolism to alpha-ketoglutarate|histidine catabolic process to 2-ketoglutarate|histidine degradation to 2-oxoglutarate|histidine catabolism to 2-ketoglutarate|histidine breakdown to 2-oxoglutarate|histidine catabolism to alpha-oxoglutarate|histidine catabolic process to alpha-ketoglutarate The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including 2-oxoglutarate. GO:0044569 [Ni-Fe] hydrogenase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044569 Ni-Fe hydrogenase complex|nickel-iron hydrogenase complex A microbial enzyme complex which contains nickel and iron in its active site. In Acetomicrobium flavidum it is an alpha 2 beta 2 tetramer. GO:0019555 glutamate catabolic process to ornithine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019555 MetaCyc:GLUTORN-PWY glutamate breakdown to ornithine|glutamate degradation to ornithine The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including ornithine. GO:0019556 histidine catabolic process to glutamate and formamide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019556 MetaCyc:HISDEG-PWY histidine breakdown to glutamate and formamide|histidine degradation to glutamate and formamide The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including glutamate and formamide. GO:0019553 glutamate catabolic process via L-citramalate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019553 MetaCyc:GLUDEG-II-PWY glutamate degradation via L-citramalate|glutamate breakdown via L-citramalate The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate L-citramalate. GO:0019554 glutamate catabolic process to oxaloacetate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019554 glutamate breakdown to oxaloacetate|glutamate degradation to oxaloacetate The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including oxaloacetate. GO:0019551 glutamate catabolic process to 2-oxoglutarate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019551 MetaCyc:GLUTAMATE-DEG1-PWY|MetaCyc:PWY-5766 glutamate catabolic process to alpha-oxoglutarate|glutamate catabolic process to 2-ketoglutarate|glutamate catabolism to alpha-ketoglutarate|glutamate degradation to 2-oxoglutarate|glutamate catabolism to 2-ketoglutarate|glutamate breakdown to 2-oxoglutarate|glutamate catabolism to alpha-oxoglutarate|glutamate catabolic process to alpha-ketoglutarate The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including 2-oxoglutarate. GO:0019552 glutamate catabolic process via 2-hydroxyglutarate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019552 MetaCyc:P162-PWY glutamate fermentation via 2-hydroxyglutarate The anaerobic chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-hydroxyglutarate, yielding energy in the form of ATP. GO:0019550 glutamate catabolic process to aspartate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019550 MetaCyc:GLUTDEG-PWY glutamate breakdown to aspartate|glutamate degradation to aspartate The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including aspartate. GO:0044570 starch utilization system complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044570 Sus complex A bacterial cell envelope-associated multiprotein system, which binds and degrades starch. GO:0019570 L-arabinose catabolic process to 2-oxoglutarate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019570 L-arabinose degradation to 2-oxoglutarate|L-arabinose catabolic process to 2-ketoglutarate|L-arabinose catabolism to 2-ketoglutarate|L-arabinose breakdown to 2-oxoglutarate|L-arabinose catabolism to alpha-oxoglutarate|L-arabinose catabolic process to alpha-oxoglutarate|L-arabinose catabolic process to alpha-ketoglutarate|L-arabinose catabolism to alpha-ketoglutarate The chemical reactions and pathways resulting in the breakdown of L-arabinose into other compounds, including 2-oxoglutarate. GO:0044577 xylose catabolic process to ethanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044577 xylose catabolism to ethanol The anaerobic chemical reactions and pathways resulting in the breakdown of xylose, an aldopentose, where one of the resulting products is ethanol. CHEBI:140883 TG(18:2/18:2/18:2) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140883 GO:0044578 butyryl-CoA biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044578 butyryl-CoA biosynthesis The chemical reactions and pathway resulting in the formation of butyryl-CoA. GO:0044575 cellulosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044575 The assembly of a cellulosome, a macromolecular multi-enzyme complex in bacteria that facilitates the breakdown of cellulase, hemicellulase and pectin in the plant cell wall. GO:0044576 pentose catabolic process to ethanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044576 pentose catabolism to ethanol The anaerobic chemical reactions and pathways resulting in the breakdown of a pentose, any monosaccharide with a chain of five carbons, where one of the resulting products is ethanol. GO:0044573 nitrogenase P cluster assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044573 nitrogenase P cluster biosynthesis|nitrogenase P cluster maturation The biochemical reactions and pathways resulting in the formation of a P-cluster of a nitrogenase, a high-nuclearity, Fe/S-only cluster that can be viewed as two [4Fe-4S] sub-clusters sharing a gamma-6-sulfide. GO:0044574 starch utilization system complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044574 SUS complex assembly|assembly of starch utilization system complex The aggregation, arrangement and bonding together of the starch utilization system complex, a complex of cell envelope-associated proteins that degrades glycan. GO:0044571 [2Fe-2S] cluster assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044571 2Fe-2S cluster assembly|[2Fe-2S] cluster biosynthetic process The incorporation of two iron atoms and two sulfur atoms into an iron-sulfur cluster. GO:0044572 [4Fe-4S] cluster assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044572 [4Fe-4S] cluster biosynthetic process|4Fe-4S cluster assembly The incorporation of four iron atoms and four sulfur atoms into an iron-sulfur cluster. GO:0044579 butyryl-CoA biosynthetic process from acetyl-CoA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044579 butyryl-CoA biosynthesis from acetyl-CoA The chemical reactions and pathway resulting in the formation of butyryl-CoA, starting from acetyl-CoA. GO:0019568 arabinose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019568 arabinose degradation|arabinose breakdown|arabinose catabolism The chemical reactions and pathways resulting in the breakdown of arabinose, arabino-pentose. GO:0019569 L-arabinose catabolic process to xylulose 5-phosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019569 MetaCyc:ARABCAT-PWY L-arabinose degradation to xylulose 5-phosphate|L-arabinose breakdown to xylulose 5-phosphate The chemical reactions and pathways resulting in the breakdown of L-arabinose into other compounds, including xylulose 5-phosphate. GO:0019566 arabinose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019566 arabinose metabolism The chemical reactions and pathways involving arabinose, arabino-pentose. L-Arabinose occurs both free, for example in the heartwood of many conifers, and in the combined state, as a constituent of plant hemicelluloses, bacterial polysaccharides etc. D-arabinose is a constituent of arabinonucleosides. GO:0019567 arabinose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019567 arabinose synthesis|arabinose formation|arabinose biosynthesis|arabinose anabolism The chemical reactions and pathways resulting in the formation of arabinose, arabino-pentose. GO:0019564 aerobic glycerol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019564 MetaCyc:PWY0-381 aerobic glycerol catabolism|aerobic glycerol degradation|aerobic glycerol fermentation|aerobic glycerol breakdown The chemical reactions and pathways resulting in the breakdown of glycerol, 1,2,3-propanetriol, in the presence of oxygen. GO:0019565 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019565 GO:0019562 obsolete L-phenylalanine catabolic process to phosphoenolpyruvate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019562 MetaCyc:PHENYLALANINE-DEG1-PWY phenylalanine breakdown to phosphoenolpyruvate|phenylalanine degradation to phosphoenolpyruvate OBSOLETE. The chemical reactions and pathways resulting in the breakdown of L-phenylalanine into other compounds, including phosphoenolpyruvate. GO:0019563 glycerol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019563 MetaCyc:PWY0-381|MetaCyc:PWY-4261 glycerol breakdown|glycerol catabolism|glycerol degradation The chemical reactions and pathways resulting in the breakdown of glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids. GO:0019560 histidine catabolic process to hydantoin-5-propionate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019560 MetaCyc:HISHP-PWY histidine breakdown to hydantoin-5-propionate|histidine degradation to hydantoin-5-propionate The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including hydantoin-5-propionate. GO:0019561 anaerobic phenylalanine oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019561 MetaCyc:ANAPHENOXI-PWY The chemical reactions and pathways resulting in the breakdown of phenylalanine under anaerobic conditions; occurs via the intermediates phenylpyruvate and phenylacetaldehyde. GO:0044580 butyryl-CoA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044580 butyryl-CoA catabolism The chemical reactions a resulting in the resulting in the breakdown of butyryl-CoA. GO:0044581 butyryl-CoA catabolic process to butyrate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044581 butyryl-CoA catabolism to butyrate The chemical reactions a resulting in the resulting in the breakdown of butyryl-CoA to form butyrate. GO:0044588 laminaribiose binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044588 Interacting selectively and non-covalently with laminaribiose, a disaccharide. GO:0044589 pectin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044589 Interacting selectively and non-covalently with pectin. GO:0044586 cellotetraose binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044586 Interacting selectively and non-covalently with cellotetraose, an oligosaccharide consisting of four glucose residues resulting from hydrolysis of cellulose. GO:0044587 cellopentaose binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044587 Interacting selectively and non-covalently with cellopentaose, an oligosaccharide consisting of four glucose residues resulting from hydrolysis of cellulose. GO:0044584 cellodextrin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044584 Interacting selectively and non-covalently with cellodextrin, a glucose polymer of 2 or more glucose monomers. GO:0044585 cellobiose binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044585 Interacting selectively and non-covalently with cellobiose, a disaccharide that represents the basic repeating unit of cellulose. GO:0044582 butyryl-CoA catabolic process to butanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044582 butyryl-CoA catabolism to butanol The chemical reactions a resulting in the resulting in the breakdown of butyryl-CoA to form butanol. GO:0044583 cellotriose binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044583 Interacting selectively and non-covalently with cellotriose. GO:0019539 siderophore biosynthetic process from hydroxamic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019539 siderophore formation from hydroxamic acid|siderophore biosynthetic process from hydroxamic acid, peptide formation|siderophore synthesis from hydroxamic acid|siderophore anabolism from hydroxamic acid|siderophore biosynthetic process from hydroxamic acid, peptide modification|siderochrome biosynthesis from hydroxamic acid|siderochrome biosynthetic process from hydroxamic acid The chemical reactions and pathways resulting in the formation of a siderophore from other compounds, including hydroxamic acid. GO:0019537 vibriobactin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019537 vibriobactin biosynthetic process, peptide modification|vibriobactin synthesis|vibriobactin formation|vibriobactin biosynthesis|vibriobactin biosynthetic process, peptide formation|vibriobactin anabolism The chemical reactions and pathways resulting in the formation of vibriobactin, the major siderophore produced by Vibrio cholerae. GO:0019538 protein metabolic process biolink:BiologicalProcess go-plus goslim_mouse|goslim_agr|goslim_pir|goslim_plant|goslim_flybase_ribbon http://purl.obolibrary.org/obo/GO_0019538 Wikipedia:Protein_metabolism protein metabolism|multicellular organismal protein metabolic process|protein metabolic process and modification|protein metabolism and modification The chemical reactions and pathways involving a protein. Includes protein modification. GO:0019535 ferric-vibriobactin transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019535 Enables the transfer of ferric-vibriobactin ions from one side of a membrane to the other. GO:0019536 vibriobactin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019536 vibriobactin metabolism The chemical reactions and pathways involving vibriobactin, the major siderophore produced by Vibrio cholerae. GO:0019533 cellobiose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019533 The directed movement of cellobiose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Cellobiose, or 4-O-beta-D-glucopyranosyl-D-glucose, is a disaccharide that represents the basic repeating unit of cellulose. GO:0019534 toxin transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019534 Enables the transfer of a toxin from one side of a membrane to the other. A toxin is a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism. GO:0019531 oxalate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019531 oxalic acid transporter activity Enables the transfer of oxalate from one side of a membrane to the other. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals. GO:0019532 oxalate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019532 ethanedioate transport|ethanedioic acid transport|oxalic acid transport The directed movement of oxalate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals. UBERON:0004500 skeletal muscle tissue of deltoid biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004500 skeletal muscle tissue of deltoid muscle A portion of skeletal muscle tissue that is part of a deltoid [Automatically generated definition]. GO:0019530 taurine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019530 taurine metabolism The chemical reactions and pathways involving taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats. GO:0044591 response to amylopectin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044591 A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of amylopectin stimulus. GO:0044592 response to pullulan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044592 A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of pullulan stimulus. GO:0044590 iron-sulfur-molybdenum cofactor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044590 FeMoco binding|FeMo co binding Interacting selectively and non-covalently with iron molybdenum cofactor, the cofactor located at the active site of the molybdenum nitrogenase. GO:0044599 AP-5 adaptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044599 adaptor protein-5 adaptor complex An AP-type membrane coat adaptor complex that in humans consists of beta5, zeta, mu5 and sigma5 subunits and is found associated with membranes in the endosomes; it is not clear whether AP-5 forms clathrin coats in vivo. GO:0044597 daunorubicin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044597 The chemical reactions and pathways involving daunorubicin, a chemotherapeutic of the anthracycline family that is given as a treatment for some types of cancer. GO:0044598 doxorubicin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044598 The chemical reactions and pathways involving doxorubicin, an anthracycline antibiotic, used in cancer chemotherapy. GO:0044595 decaprenyldihydroxybenzoate methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044595 MetaCyc:RXN-9282|RHEA:44492|Reactome:R-HSA-2162193 Catalysis of the reaction: S-adenosyl-L-methionine + 3-decaprenyl-4,5-dihydroxybenzoate = S-adenosyl-L-homocysteine + 3-decaprenyl-4-hydroxy-5-methoxybenzoate. GO:0044596 3-demethylubiquinol-10 3-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044596 Reactome:R-HSA-2162186|MetaCyc:RXN-9237|RHEA:44412 Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinol-10 = S-adenosyl-L-homocysteine + ubiquinol-10. GO:0044593 iron-sulfur-molybdenum cofactor assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044593 FeMoco biosynthetic process|iron molybdenum cofactor biosynthetic process|iron molybdenum cofactor biosynthesis|FeMoco assembly|iron molybdenum cofactor assembly The chemical reactions and pathways resulting in the formation of iron-sulfur-molybdenum cofactor, the cofactor located at the active site of the molybdenum nitrogenase. GO:0044594 17-beta-hydroxysteroid dehydrogenase (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044594 RHEA:24612 Catalysis of the reaction: a 17-beta-hydroxysteroid + NAD+ = a 17-oxosteroid + NADH + H+. CHEBI:57594 O-carbamoyl-L-serine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57594 CHEBI:57595 L-histidine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57595 CHEBI:57592 cyclohexylsulfamate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57592 CHEBI:57593 3-guanidinopropanoic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57593 CHEBI:57590 O-phosphonato-L-homoserine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57590 GO:0019548 arginine catabolic process to spermine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019548 MetaCyc:ARGSPECAT-PWY arginine degradation to spermine|arginine breakdown to spermine The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including spermine. GO:0019549 glutamate catabolic process to succinate via succinate semialdehyde biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019549 MetaCyc:PWY-4321 glutamate catabolic process to succinate via pyruvate-dependent GABA-transaminase activity|glutamate breakdown to succinate|glutamate degradation to succinate The chemical reactions and pathways resulting in the breakdown of glutamate into succinate, that includes the conversion of 4-aminobutyrate to succinate semialdehyde by the pyruvate-dependent gamma aminobutyrate (GABA) transaminase. GO:0019546 arginine deiminase pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019546 MetaCyc:ARGDEGRAD-PWY The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including ornithine and CO2, using the enzyme arginine deiminase. GO:0019547 arginine catabolic process to ornithine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019547 arginine breakdown to ornithine|arginine degradation to ornithine The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including ornithine. GO:0019544 arginine catabolic process to glutamate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019544 MetaCyc:ARGASEDEG-PWY|MetaCyc:ARG-GLU-PWY arginine breakdown to glutamate|arginine degradation to glutamate The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including glutamate. GO:0019545 arginine catabolic process to succinate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019545 MetaCyc:ARGDEG-IV-PWY|MetaCyc:AST-PWY|MetaCyc:ARGDEG-V-PWY|MetaCyc:ARGDEG-III-PWY arginine breakdown to succinate|arginine degradation to succinate The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including succinate. GO:0019542 propionate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019542 propionate biosynthesis|propionate formation|propionate anabolism|propionate synthesis The chemical reactions and pathways resulting in the formation of propionate, the anion derived from propionic acid. GO:0019543 propionate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019543 propionate degradation|propionate breakdown|propionate catabolism The chemical reactions and pathways resulting in the breakdown of propionate, the anion derived from propionic acid. GO:0019540 siderophore biosynthetic process from catechol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019540 siderophore biosynthetic process from catechol, peptide formation|siderophore anabolism from catechol|siderophore synthesis from catechol|siderophore formation from catechol|siderochrome biosynthetic process from catechol|siderochrome biosynthesis from catechol|siderophore biosynthetic process from catechol, peptide modification The chemical reactions and pathways resulting in the formation of a siderophore from other compounds, including catechol. CHEBI:57598 1-benzyl-2-methyl-1,2,3,4-tetrahydroisoquinolinium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57598 GO:0019541 propionate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019541 propionate metabolism|propanoate metabolic process|propanoate metabolism The chemical reactions and pathways involving propionate, the anion derived from propionic (propanoic) acid, a carboxylic acid important in the energy metabolism of ruminants. CHEBI:57599 N-acyl-D-glucosamine 6-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57599 CHEBI:57596 dTDP-4-amino-4,6-dideoxy-D-galactose(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57596 CHEBI:57597 sn-glycerol 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57597 GO:0019519 pentitol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019519 pentitol metabolism The chemical reactions and pathways involving pentitols, any alditol with a chain of five carbon atoms in the molecule. CHEBI:57583 6-imino-5-oxocyclohexa-1,3-diene-1-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57583 CHEBI:57584 aldehydo-D-glucose 6-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57584 GO:0019517 L-threonine catabolic process to D-lactate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019517 MetaCyc:THRDLCTCAT-PWY L-threonine breakdown to D-lactate|L-threonine catabolism to D-lactate|L-threonine degradation to D-lactate|threonine catabolic process to D-lactate|L-threonine catabolic process to methylglyoxal|L-threonine catabolic process to pyruvate|L-threonine catabolic process to (R)-lactate The chemical reactions and pathways resulting in the breakdown of L- threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form the compound methylglyoxal, which is subsequently converted to D-lactate. CHEBI:57581 (S)-coclaurinium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57581 GO:0019518 L-threonine catabolic process to glycine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019518 MetaCyc:THREONINE-DEG2-PWY threonine catabolic process to glycine|L-threonine degradation to glycine|L-threonine catabolic process to pyruvate|L-threonine catabolism to glycine|L-threonine breakdown to glycine The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form to form 2-amino-3-oxobutanoate, which is subsequently converted to glycine. CHEBI:57582 dTDP-4-amino-4,6-dideoxy-D-glucose(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57582 GO:0019515 lactose catabolic process via UDP-galactose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019515 lactose degradation via UDP-galactose|lactose breakdown via UDP-galactose The chemical reactions and pathways resulting in the breakdown of lactose, via the intermediate UDP-galactose. CHEBI:57580 diphthamide zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57580 GO:0019516 lactate oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019516 The chemical reactions and pathways resulting in the conversion of lactate to other compounds, such as pyruvate, with concomitant loss of electrons. GO:0019513 lactose catabolic process, using glucoside 3-dehydrogenase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019513 MetaCyc:LACTOSEUTIL-PWY lactose breakdown, using glucoside 3-dehydrogenase|lactose degradation, using glucoside 3-dehydrogenase The chemical reactions and pathways resulting in the breakdown of lactose, catalyzed by the enzyme glucoside 3-dehydrogenase (EC:1.1.99.13). GO:0019514 obsolete lactose hydrolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019514 lactose hydrolysis OBSOLETE. (Was not defined before being made obsolete). GO:0019511 peptidyl-proline hydroxylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019511 The hydroxylation of peptidyl-proline to form peptidyl-hydroxyproline. GO:0019512 lactose catabolic process via tagatose-6-phosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019512 MetaCyc:LACTOSECAT-PWY lactose breakdown via tagatose-6-phosphate|lactose degradation via tagatose-6-phosphate The chemical reactions and pathways resulting in the breakdown of lactose, via the intermediate tagatose-6-phosphate. CHEBI:57589 O-acetyl-L-carnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57589 GO:0019510 S-adenosylhomocysteine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019510 MetaCyc:ADENOSYLHOMOCYSCAT-PWY S-adenosylhomocysteine degradation|S-adenosylhomocysteine breakdown|S-adenosylhomocysteine catabolism The chemical reactions and pathways resulting in the breakdown of S-adenosylhomocysteine, forming homocysteine and then methionine. CHEBI:57587 stipitatate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_57587 CHEBI:57588 phosphatidyl-N-methylethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57588 CHEBI:57585 discadenine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57585 CHEBI:57586 biotinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57586 CHEBI:57572 UDP-D-apiose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57572 GO:0019528 D-arabitol catabolic process to xylulose 5-phosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019528 MetaCyc:DARABITOLUTIL-PWY D-arabitol degradation|D-arabitol utilization|D-arabitol degradation to xylulose 5-phosphate|D-arabitol breakdown to xylulose 5-phosphate The chemical reactions and pathways resulting in the breakdown of D-arabitol to form xylulose 5-phosphate. D-arabitol is converted into D-xylulose, which is then phosphorylated to form D-xylulose-5-phosphate. CHEBI:57570 dolichyl diphosphooligosaccharide(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57570 GO:0019529 taurine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019529 MetaCyc:TAURINEDEG-PWY taurine degradation|taurine catabolism|taurine breakdown The chemical reactions and pathways resulting in the breakdown of taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats. GO:0019526 pentitol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019526 pentitol anabolism|pentitol synthesis|pentitol formation|pentitol biosynthesis The chemical reactions and pathways resulting in the formation of pentitols, any alditol with a chain of five carbon atoms in the molecule. GO:0019527 pentitol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019527 pentitol breakdown|pentitol catabolism|pentitol degradation The chemical reactions and pathways resulting in the breakdown of pentitols, any alditol with a chain of five carbon atoms in the molecule. GO:0019524 keto-D-gluconate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019524 MetaCyc:DHGLUCONATE-PYR-CAT-PWY keto-D-gluconate degradation|keto-D-gluconate breakdown|keto-D-gluconate catabolism The chemical reactions and pathways resulting in the breakdown of keto-D-gluconate, the anion of keto-D-gluconic acid, an aldonic acid derived from glucose. GO:0019525 keto-D-gluconate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019525 keto-D-gluconate metabolism The chemical reactions and pathways involving keto-D-gluconate, the anion of keto-D-gluconic acid, an aldonic acid derived from glucose. GO:0019522 ketogluconate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019522 MetaCyc:KETOGLUCONMET-PWY ketogluconate metabolism The chemical reactions and pathways involving ketogluconate, the anion of ketogluconic acid, an aldonic acid derived from glucose containing a ketonic carbonyl group. GO:0019523 L-idonate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019523 MetaCyc:IDNCAT-PWY L-idonate metabolism The chemical reactions and pathways involving L-idonate, the anion of idonic acid, an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose. CHEBI:57578 6-O-methylnorlaudanosolinium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57578 GO:0019520 aldonic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019520 aldonic acid metabolism The chemical reactions and pathways involving aldonic acid, a monocarboxylic acid with a chain of three or more carbon atoms, derived from an aldose by oxidation of the aldehydic group. CHEBI:57579 D-fructose 6-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57579 GO:0019521 D-gluconate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019521 D-gluconate metabolism The chemical reactions and pathways involving D-gluconate, the anion of D-gluconic acid, the aldonic acid derived from glucose. CHEBI:57576 2,3-dihydroxy-2,3-dihydrobenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57576 CHEBI:57577 poly(glycerol phosphate) anion macromolecule biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57577 CHEBI:57575 trans-5-O-(4-coumaroyl)-D-quinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57575 GO:0044500 envenomation resulting in negative regulation of blood pressure in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044500 hypotensive activity in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant decrease of the force with which blood travels through the circulatory system of the bitten/stung organism. GO:0044501 modulation of signal transduction in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044501 The process in which an organism effects a change in a signal transduction process - a cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell - in a second organism. GO:0044508 glucagon-like peptide 1 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044508 Combining with glucagon-like peptide 1 and transmitting the signal across the membrane by activating an associated G-protein. GO:0044509 envenomation resulting in modulation of signal transduction in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044509 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of signal transduction in the bitten organism. GO:0044506 modulation of glucagon-like peptide receptor 1 activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044506 regulation of glucagon-like peptide receptor activity in other organism The process in which an organism effects a change in the activity of a glucagon-like peptide receptor 1 in a second organism. GO:0044507 positive regulation of receptor activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044507 A process that activates or increases the frequency, rate or extent of the activity of a receptor in a second organism. GO:0044504 modulation of receptor activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044504 The process in which an organism effects a change in the activity of a receptor in a second organism. GO:0044505 positive regulation of G protein-coupled receptor activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044505 regulation of G-protein coupled receptor activity in other organism|positive regulation of G-protein coupled receptor activity in other organism A process that activates or increases the frequency, rate or extent of the activity of a G protein-coupled receptor in a second organism. GO:0044502 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044502 GO:0044503 modulation of G protein-coupled receptor activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044503 modulation of G-protein coupled receptor activity in other organism The process in which an organism effects a change in the activity of a G protein-coupled receptor in a second organism. GO:0044511 envenomation resulting in modulation of receptor activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044511 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of receptor activity in of the bitten organism. GO:0044512 envenomation resulting in modulation of glucagon-like peptide receptor 1 activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044512 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of glucagon-like peptide receptor 1 activity in of the bitten organism. GO:0044510 envenomation resulting in positive regulation of signal transduction in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044510 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of signal transduction in the bitten organism. GO:0044519 envenomation resulting in modulation of vasoactive intestinal polypeptide receptor activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044519 envenomation resulting in regulation of vasoactive intestinal polypeptide receptor activity in other organism|envenomation resulting in regulation of VIP receptor activity in other organism|envenomation resulting in modulation of VIP receptor activity in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of the activity of a vasoactive intestinal polypeptide receptor in the bitten organism. GO:0044517 modulation of vasoactive intestinal polypeptide receptor activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044517 regulation of vasoactive intestinal polypeptide receptor activity in other organism|modulation of VIP receptor activity in other organism The process in which an organism effects a change in the activity of a vasoactive intestinal polypeptide receptor in a second organism. GO:0044518 positive regulation of vasoactive intestinal polypeptide receptor activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044518 positive regulation of VIP receptor activity in other organism A process that activates or increases the frequency, rate or extent of the activity of a vasoactive intestinal polypeptide receptor in a second organism. GO:0044515 envenomation resulting in positive regulation of glucagon-like peptide receptor 1 activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044515 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of glucagon-like peptide receptor 1 activity in of the bitten organism. GO:0044516 positive regulation of glucagon-like peptide receptor 1 activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044516 A process that activates or increases the frequency, rate or extent of the activity of a glucagon-like peptide receptor 1 in a second organism. GO:0044513 envenomation resulting in modulation of G protein-coupled receptor activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044513 envenomation resulting in modulation of G-protein coupled receptor activity in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of G protein-coupled receptor activity in of the bitten organism. GO:0044514 envenomation resulting in positive regulation of G protein-coupled receptor activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044514 envenomation resulting in positive regulation of G-protein coupled receptor activity in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of G protein-coupled receptor activity in of the bitten organism. GO:0044522 envenomation resulting in myocyte killing in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044522 envenomation resulting in myocyte killing causing muscle damage in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, killing heart myocytes and ultimately resulting in muscle damage in the bitten organism. GO:0044523 envenomation resulting in damage of muscle extracellular matrix in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044523 envenomation resulting in damage of muscle extracellular matrix causing muscle necrosis in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, damaging the extracellular matrix of muscle cells and ultimately resulting in muscle necrosis in the bitten organism. GO:0044520 envenomation resulting in positive regulation of vasoactive intestinal polypeptide receptor activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044520 envenomation resulting in positive regulation of VIP receptor activity in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of the activity of a vasoactive intestinal polypeptide receptor in the bitten organism. GO:0044521 envenomation resulting in muscle damage in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044521 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with resultant muscle damage in the bitten organism. PR:000008878 bone sialoprotein 2 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000008878 BNSP|BSP II|cell-binding sialoprotein|integrin-binding sialoprotein|IBSP|bone sialoprotein II A protein that is a translation product of the human IBSP gene or a 1:1 ortholog thereof. GO:0044528 regulation of mitochondrial mRNA stability biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044528 Any process that modulates the propensity of mitochondrial mRNA molecules to degradation. Includes processes that both stabilize and destabilize mitochondrial mRNAs. GO:0044529 regulation of mitochondrial rRNA stability biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044529 Any process that modulates the propensity of mitochondrial rRNA molecules to degradation. Includes processes that both stabilize and destabilize mitochondrial rRNAs. GO:0044526 formation of peptidyl-cystine persulfide by sulphur transfer from free cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044526 The modification of a peptidyl-cystine residue in a protein by the transfer of a sulfur atom from a free cysteine (in the process converting the free cysteine to alanine) to the peptidyl-cysteine to form peptidyl-cysteine persulfide. PR:000008875 islet amyloid polypeptide biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000008875 DAP|amylin|diabetes-associated peptide|IAPP|insulinoma amyloid peptide A protein that is a translation product of the human IAPP gene or a 1:1 ortholog thereof. GO:0044527 formation of peptidyl-cystine persulfide by sulphur transfer from H2S biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044527 The modification of a peptidyl-cystine residue in a protein by the direct addition of H2S, followed by the removal of 2 protons to form peptidyl-cysteine persulfide. GO:0044524 protein sulfhydration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044524 The modification of a protein amino acid by the addition of sulfur. GO:0044525 peptidyl-cystine sulfhydration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044525 The modification of a peptidyl-cystine residue in a protein by the addition of sulfur, to form peptidyl-cysteine persulfide. GO:0019599 (R)-4-hydroxymandelate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019599 MetaCyc:4-HYDROXYMANDELATE-DEGRADATION-PWY (R)-4-hydroxymandelate degradation|(R)-4-hydroxymandelate catabolism|(R)-4-hydroxymandelate breakdown The chemical reactions and pathways resulting in the breakdown of (R)-4-hydroxymandelate, the anion of (R)-4-hydroxymandelic acid. GO:0019597 (R)-mandelate catabolic process to benzoate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019597 (R)-mandelate degradation to benzoate|(R)-mandelate breakdown to benzoate The chemical reactions and pathways resulting in the breakdown of (R)-mandelate into other compounds, including benzoate. GO:0019598 (R)-mandelate catabolic process to catechol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019598 (R)-mandelate breakdown to catechol|(R)-mandelate degradation to catechol The chemical reactions and pathways resulting in the breakdown of (R)-mandelate into other compounds, including catechol. GO:0019595 non-phosphorylated glucose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019595 MetaCyc:NPGLUCAT-PWY non-phosphorylated glucose catabolism|non-phosphorylated glucose degradation|non-phosphorylated glucose breakdown The chemical reactions and pathways resulting in the breakdown of non-phosphorylated forms of glucose. GO:0019596 mandelate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019596 mandelate degradation|mandelate breakdown|mandelate catabolism The chemical reactions and pathways resulting in the breakdown of mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic. GO:0019593 mannitol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019593 MetaCyc:PWY-3881 mannitol anabolism|mannitol synthesis|mannitol biosynthesis|mannitol formation The chemical reactions and pathways resulting in the formation of mannitol, the alditol derived from D-mannose by reduction of the aldehyde group. GO:0019594 mannitol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019594 mannitol metabolism The chemical reactions and pathways involving mannitol, the alditol derived from D-mannose by reduction of the aldehyde group. GO:0044533 positive regulation of apoptotic process in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044533 Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death by apoptosis in a second organism. GO:0044534 envenomation resulting in modulation of apoptotic process in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044534 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of apoptosis in the bitten organism. GO:0044531 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044531 GO:0044532 modulation of apoptotic process in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044532 regulation of apoptotic process in other organism A process in which an organism modulates the frequency, rate or extent of apoptosis in a second organism. GO:0044530 supraspliceosomal complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044530 supraspliceosome complex Multicomponent complex of RNA and proteins that is composed of four active spliceosomes, termed native spliceosomes, connected to each other by the pre-mRNA. The supraspliceosome is the nuclear machine where the pre-mRNA processing takes place, like the 5'-end capping, 3'-end cleavage, splicing and editing. GO:0044539 long-chain fatty acid import into cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044539 long-chain fatty acid uptake|long-chain fatty acid import The directed movement of a long-chain fatty acid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22. GO:0044537 regulation of circulating fibrinogen levels biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044537 Any process that modulates the quantity of fibrinogen circulating in the bloodstream. GO:0044538 host cell periphery biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044538 The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures of a host cell. GO:0044535 very-long-chain fatty acyl-CoA oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044535 EC:1.3.3.- very-long-chain acyl-CoA oxidase activity|VLC fatty-acyl-CoA oxidase activity|very long chain fatty-acyl-CoA oxidase activity Catalysis of the reaction: very-long-chain fatty acyl-CoA (C22 - C24) + O2 = trans-2,3-dehydroacyl-CoA + hydrogen peroxide. GO:0044536 envenomation resulting in depletion of circulating fibrinogen in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044536 envenomation resulting in negative regulation of circulating fibrinogen in other organism The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with a reduction in the quantity of fibrinogen found in the bloodstream of the bitten/stung organism. PR:000008888 isocitrate dehydrogenase [NADP], mitochondrial biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000008888 oxalosuccinate decarboxylase|ICD-M|IDP|IDH2nadp|IDH|NADP(+)-specific ICDH A protein that is a translation product of the human IDH2 gene or a 1:1 ortholog thereof. CHEBI:33515 transition element cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33515 CHEBI:33516 chromium cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33516 CHEBI:33519 tellurium oxoacid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33519 CHEBI:33510 L-arabinonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33510 CHEBI:33511 ribonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33511 CHEBI:33513 alkaline earth cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33513 CHEBI:33526 mannonate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33526 CHEBI:33527 ribonate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33527 CHEBI:33529 idonate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33529 CHEBI:33520 tellurium oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33520 CHEBI:33521 metal atom biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33521 CHEBI:33522 hydrogentellurite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33522 CHEBI:33504 alkali metal cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33504 CHEBI:33507 diketoaldonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33507 CHEBI:33508 glyceric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33508 CHEBI:33509 arabinonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33509 UBERON:0004590 sphincter muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004590 sphincter|circular muscle A structure, usually a circular muscle, that normally maintains constriction of a natural body passage or orifice and which relaxes as required by normal physiological functioning. UBERON:0004538 left kidney biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004538 A kidney that is part of a left side of organism [Automatically generated definition]. UBERON:0004539 right kidney biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004539 A kidney that is part of a right side of organism [Automatically generated definition]. CHEBI:57561 L-threonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57561 CHEBI:57562 (R)-2-hydroxyoctadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57562 CHEBI:33595 cyclic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33595 CHEBI:33596 inorganic heterocyclic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33596 CHEBI:57560 long-chain fatty acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57560 CHEBI:33597 homocyclic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33597 CHEBI:33598 carbocyclic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33598 CHEBI:33599 spiro compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33599 CHEBI:57569 2-dehydro-3-deoxy-6-phosphonato-D-gluconate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57569 UBERON:0004548 left eye biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004548 left eyeball|left orbital part of face|left orbital region An eye that is part of a left side of organism [Automatically generated definition]. CHEBI:57567 N(6)-(1,2-dicarboxylatoethyl)-AMP(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57567 CHEBI:57565 serine phosphoethanolamine dizwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57565 UBERON:0004544 epididymis epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004544 epithelium of epididymis|epididymis epithelium the layer of secretory cells which lines the epididymis CHEBI:57566 2'-deoxycytosine 5'-monophosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57566 CHEBI:57563 2-amino-4-oxopentanoic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57563 CHEBI:57564 ADP-L-glycero-D-manno-heptose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57564 UBERON:0004529 anatomical projection biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004529 spine|papilla|protrusion|lamella|anatomical protrusion|lamellae|flange|projection|ridge|shelf|projection|shelves|ridges|processus|lamina|projections|flanges|laminae|anatomical process|organ process|process|processes|process of organ A projection or outgrowth of tissue from a larger body or organ. UBERON:0004527 alveolar process of maxilla biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004527 alveolar process of maxilla|maxilla alveolar process|processus alveolaris (maxilla)|posterior alveolar ridge|lower alveolar ridge|alveolar margin of maxilla|pars dentalis of maxilla|alveolar part of maxilla|processus alveolaris maxillae|alveolar ridge of maxilla The thickened ridge of bone that contains the tooth sockets on the maxilla. GO:0019508 2,5-dihydroxypyridine catabolic process to fumarate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019508 MetaCyc:PWY-722 pyridine-2,5-diol catabolic process to fumarate|2,5-dihydroxypyridine degradation to fumarate|maleamate pathway|2,5-dihydroxypyridine breakdown to fumarate|2,5-dihydroxypyridine utilization The chemical reactions and pathways resulting in the breakdown of 2,5-dihydroxypyridine to form fumarate. 2,5-dihydroxypyridine is dioxygenated to give maleamate and formate; the maleamate from this reaction is then converted to maleate, which is then isomerized to fumurate. CHEBI:57551 S-methyl 3-O-phosphonato-1-thio-D-glycerate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57551 GO:0019509 L-methionine salvage from methylthioadenosine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019509 MetaCyc:PWY-4361 methionine recycling|methionine salvage pathway|methionine salvage from methylthioadenosine|methionine regeneration The generation of L-methionine (2-amino-4-(methylthio)butanoic acid) from methylthioadenosine. GO:0019506 phenylmercury acetate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019506 MetaCyc:P641-PWY phenylmercury acetate degradation|phenylmercury acetate breakdown|phenylmercury acetate catabolism The chemical reactions and pathways resulting in the breakdown of phenylmercury acetate, an organomercurial compound composed of a mercury atom attached to a benzene ring and an acetate group. GO:0019507 pyridine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019507 pyridine metabolism The chemical reactions and pathways involving pyridine, a nitrogenous base (C5H5N) obtained from the distillation of bone oil or coal tar, and by the decomposition of certain alkaloids, as a colorless liquid with a peculiar pungent odor. GO:0019504 stachydrine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019504 MetaCyc:P561-PWY stachydrine degradation|stachydrine breakdown|stachydrine catabolism The chemical reactions and pathways resulting in the breakdown of stachydrine, N-methylproline methylbetaine, the betaine derivative of L-proline. GO:0019505 resorcinol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019505 MetaCyc:P343-PWY resorcinol metabolism|1,3-benzenediol metabolic process|1,3-dihydroxybenzene metabolic process|1,3-dihydroxybenzene metabolism|1,3-benzenediol metabolism The chemical reactions and pathways involving resorcinol (C6H4(OH)2), a benzene derivative with many applications, including dyes, explosives, resins and as an antiseptic. GO:0019502 stachydrine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019502 stachydrine metabolism The chemical reactions and pathways involving stachydrine, N-methylproline methylbetaine, the betaine derivative of L-proline found in alfalfa, chrysanthemum, and citrus plants. GO:0019503 stachydrine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019503 stachydrine anabolism|stachydrine synthesis|stachydrine formation|stachydrine biosynthesis The chemical reactions and pathways resulting in the formation of stachydrine, N-methylproline methylbetaine, the betaine derivative of L-proline. UBERON:0004536 lymph vasculature biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004536 lymphatic vasculature|lymphatic vessels set|lymphatic trunks and ducts|lymphatic vessel network|set of lymphatic vessels|trunci et ductus lymphatici|lymph vessels A network of blunt ended vessels lacking direct connection to the blood vascular system. These vessels collect and drain fluids and macromolecules from interstitial spaces throughout the animal. They derive from a subpopulation of endothelial cells and have walls that are much thinner than the blood carrying vessels. Lymphatic vessels are usually classified as either superficial or deep. CHEBI:57558 trans-2,3-epoxysuccinate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57558 GO:0019500 cyanide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019500 MetaCyc:P401-PWY cyanide degradation|cyanide breakdown|cyanide catabolism The chemical reactions and pathways resulting in the breakdown of cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration. CHEBI:57559 alpha-D-xylose 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57559 UBERON:0004537 blood vasculature biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004537 blood vascular network|blood vessels|blood system|blood vessel system|set of blood vessels A vascular network consisting of blood vessels. GO:0019501 arsonoacetate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019501 MetaCyc:P482-PWY arsonoacetate catabolism|arsonoacetate degradation|arsonoacetate breakdown The chemical reactions and pathways resulting in the breakdown of arsonoacetate, a synthetic, organic compound containing a single arsenic atom. UBERON:0004534 right testis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004534 right testicle A testis that is in the right side of the genitalia [Automatically generated definition]. CHEBI:57556 S-(3-carboxylatopropanoyl)glutathionate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57556 UBERON:0004535 cardiovascular system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004535 Herz und Gefaesssystem|CV system Anatomical system that has as its parts the heart and blood vessels. CHEBI:57557 (R)-5-diphosphonatomevalonate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57557 CHEBI:57554 tropinium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57554 CHEBI:57555 L-2-amino-4-chloropent-4-enoic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57555 UBERON:0004533 left testis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004533 left testicle A testis that is in the left side of the genitalia [Automatically generated definition]. CHEBI:57552 2-oxopropyl-CoM(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57552 UBERON:0004530 bony projection biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004530 projection of bone|bony projections|bone process Anatomical projection that is composed of bone tissue. CHEBI:57553 P(1),P(4)-bis(5'-guanosyl) tetraphosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57553 UBERON:0004518 muscle of vertebral column biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004518 vertebral column muscle A muscle that is attached to a vertebra of the vertebral column. UBERON:0004516 smooth muscle tissue of terminal bronchiole biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004516 A portion of smooth muscle tissue that is part of a terminal bronchiole [Automatically generated definition]. CHEBI:57549 N(2)-(carboxylatoacetyl)-D-tryptophanate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57549 CHEBI:33572 resorcinols biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33572 CHEBI:33573 tetrol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33573 CHEBI:57540 NAD(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57540 CHEBI:33574 4-methylthio-2-oxobutanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33574 CHEBI:33575 carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33575 CHEBI:33576 sulfur-containing carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33576 CHEBI:33579 main group molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33579 UBERON:0004525 cardiac muscle tissue of trabecula carnea of right ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004525 A portion of trabecula carnea cardiac muscle tissue that is part of a right ventricle [Automatically generated definition]. CHEBI:57547 CDP-N-methylethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57547 UBERON:0004526 cardiac muscle tissue of trabecula carnea of left ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004526 A portion of trabecula carnea cardiac muscle tissue that is part of a left ventricle [Automatically generated definition]. CHEBI:57548 o-orsellinate depsidate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57548 CHEBI:57545 2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxo-4H-chromen-7-olate luteolin-7-olate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57545 UBERON:0004521 vasculature of muscle organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004521 muscular organ vasculature A vasculature that is part of a muscle organ [Automatically generated definition]. CHEBI:57543 3-(uracil-1-yl)-L-alanine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57543 UBERON:0004522 vasculature of musculoskeletal system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004522 A vasculature that is part of a musculoskeletal system [Automatically generated definition]. CHEBI:57541 2-(alpha-D-mannosyl)-D-glycerate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57541 CHEBI:33570 benzenediols biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33570 UBERON:0004520 striated muscle tissue of prostate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004520 A portion of striated muscle tissue that is part of a prostate gland [Automatically generated definition]. CHEBI:57542 aryl(methyl)malonate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57542 CHEBI:33571 (S)-noradrenaline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33571 UBERON:0004509 skeletal muscle tissue of trapezius biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004509 skeletal muscle tissue of trapezius muscle A portion of skeletal muscle tissue that is part of a trapezius [Automatically generated definition]. CHEBI:57538 orotidine 5'-phosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57538 CHEBI:57539 1D-myo-inositol 3,4,5,6-tetrakisphosphate(8-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57539 CHEBI:140922 glioma-associated oncogene inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_140922 CHEBI:33585 lead molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33585 CHEBI:57536 (7R)-7-(5-carboxy-5-oxopentanamido)cephalosporanate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57536 UBERON:0004515 smooth muscle tissue of bronchiole biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004515 smooth muscle tissue of lobular bronchiole A portion of smooth muscle tissue that is part of a bronchiole [Automatically generated definition]. CHEBI:57537 N-acylneuraminate 9-phosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57537 CHEBI:57534 1-acylglycerone 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57534 CHEBI:57535 4-phosphonato-L-aspartic acid(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57535 CHEBI:57532 8-amino-7-oxononanoic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57532 CHEBI:57533 geranylgeranyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57533 CHEBI:33581 boron group molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33581 CHEBI:57531 L-serine O-sulfate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57531 CHEBI:33582 carbon group molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33582 CHEBI:57529 17alpha-estradiol 3-glucosiduronate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57529 CHEBI:57527 GDP-alpha-D-mannose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57527 CHEBI:57528 5-hydroxy-6-methylpyridine-3-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57528 CHEBI:33558 alpha-amino-acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33558 CHEBI:33559 s-block element atom biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33559 CHEBI:33551 organosulfonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33551 CHEBI:33552 sulfonic acid derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33552 UBERON:0004581 systemic venous system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004581 systemic venous circulatory system The part of the venous system that drains the general body tissues[Kardong] UBERON:0004582 venous system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004582 vein system The part of the cardiovascular system consisting of all venous vessels. In vertebrates with a double circulation, this can be divided into systemic and pulmonary portions. CHEBI:33554 organosulfonate oxoanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33554 CHEBI:33555 arenesulfonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33555 CHEBI:33557 aminobenzenesulfonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33557 CHEBI:57525 dolichyl beta-D-glucosyl phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57525 CHEBI:57526 N(6)-(dimethylallyl)adenosine 5'-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57526 CHEBI:57523 dolichyl D-mannosyl phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57523 CHEBI:57524 O-phosphonato-L-serine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57524 CHEBI:57521 beta-L-arabinose 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57521 CHEBI:57522 12-dehydrotetracycline zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57522 CHEBI:57520 D-octopine dizwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57520 CHEBI:57518 1-palmitoyl-sn-glycerol 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57518 CHEBI:57519 alpha,beta-didehydrotryptophanate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_57519 CHEBI:57516 deoxylimononate D-ring-lactone(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57516 CHEBI:33569 noradrenaline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33569 CHEBI:595389 4'-demethylrebeccamycin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_595389 UBERON:0004572 arterial system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004572 The part of the cardiovascular system consisting of all arteries. CHEBI:33561 d-block element atom biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33561 UBERON:0004573 systemic artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004573 systemic arterial subtree An artery of the systemic circulation, which is the part of the cardiovascular system which carries oxygenated blood away from the heart, to the body, and returns deoxygenated blood back to the heart. CHEBI:33563 glycolipid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33563 UBERON:0004571 systemic arterial system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004571 systemic arterial circulatory system The part of the arterial system which carries oxygenated blood away from the heart to the body, and returns deoxygenated blood back to the heart. CHEBI:33564 dihydroxybenzenesulfonate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33564 CHEBI:33565 2,3-dihydroxybenzenesulfonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33565 CHEBI:33566 catechols biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33566 CHEBI:33567 catecholamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33567 CHEBI:33568 adrenaline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33568 CHEBI:57514 1-(alk-1-enyl)-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57514 CHEBI:57515 3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57515 CHEBI:57512 N-acyl-D-aspartate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57512 CHEBI:57513 N-acetyl-D-glucosamine 6-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57513 CHEBI:57510 dTDP-6-deoxy-beta-L-mannose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57510 CHEBI:57511 cephalosporin C(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57511 CHEBI:33560 p-block element atom biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33560 CHEBI:57509 L-dopachromate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57509 CHEBI:57508 D-erythritol 4-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57508 CHEBI:57505 N-benzoyl-D-argininium-4-nitroanilide(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57505 CHEBI:57506 3,5-diiodo-L-tyrosinate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57506 PATO:0002007 convex 3-D shape biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PATO_0002007 A complete three dimensional shape in which for every line connecting pair of points on the object is within the object. Or: a shape lacking cavities. Contrast: concave. CHEBI:33539 hydroxidodioxidosulfidosulfate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33539 PATO:0002006 2-D shape biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PATO_0002006 2-D projection|cross-sectional A shape that inheres in a 2 dimensional entity, such as a cross section or projection of a 3 dimensional entity. CHEBI:33530 altronate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33530 CHEBI:33532 altronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33532 CHEBI:33535 sulfur hydride biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33535 CHEBI:57503 anthocyanidin 3,5-di-O-beta-D-glucoside betaine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57503 CHEBI:57504 L-dopa zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57504 CHEBI:57501 (S)-4-amino-5-oxopentanoic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57501 CHEBI:57502 nicotinate D-ribonucleotide(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57502 UBERON:0004549 right eye biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004549 right orbital part of face|right eyeball|right orbital region An eye that is part of a right side of organism [Automatically generated definition]. CHEBI:33549 uronate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33549 CHEBI:33540 thiosulfuric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33540 CHEBI:33541 thiosulfate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33541 CHEBI:33542 trioxidosulfanidosulfate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33542 CHEBI:33543 sulfonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33543 CHEBI:33544 alpha-amino-acid radical biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33544 UBERON:0004554 hindlimb digital artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004554 hindlimb digital arteries|digital artery of foot A digital artery that is part of a hindlimb [Automatically generated definition]. UBERON:0004552 digital artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004552 An artery that is part of a digit [Automatically generated definition]. UBERON:0004553 forelimb digital artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004553 forelimb digital arteries|digital artery of manus|wing digital artery A digital artery that is part of a forelimb [Automatically generated definition]. GO:0030019 obsolete tryptase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030019 tryptase activity|rat mast cell protease II|mast cell proteinase II|mast cell serine proteinase tryptase activity|mast cell neutral proteinase activity|mast cell tryptase activity|pituitary tryptase activity|lung tryptase activity|mast cell serine proteinase II|skin tryptase activity|mast cell protease II activity|tryptase M OBSOLETE. Catalysis of the preferential cleavage of Arg-Xaa, Lys-Xaa, but with more restricted specificity than trypsin. GO:0030017 sarcomere biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030017 Wikipedia:Sarcomere The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs. GO:0030018 Z disc biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030018 Z band|Z line|Z disk Platelike region of a muscle sarcomere to which the plus ends of actin filaments are attached. GO:0030015 CCR4-NOT core complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030015 The core of the CCR4-NOT complex. In Saccharomyces the CCR4-NOT core complex comprises Ccr4p, Caf1p, Caf40p, Caf130p, Not1p, Not2p, Not3p, Not4p, and Not5p. GO:0030016 myofibril biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030016 Wikipedia:Myofibril striated muscle fibre|striated muscle fiber The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism. GO:0005057 obsolete signal transducer activity, downstream of receptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005057 receptor signalling protein activity|intracellular signal transducer activity|receptor signaling protein activity OBSOLETE. Conveys a signal from an upstream receptor or intracellular signal transducer, converting the signal into a form where it can ultimately trigger a change in the state or activity of a cell. GO:0044665 MLL1/2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044665 Trx-containing complex A protein complex that can methylate lysine-4 of histone H3, and which contains either of the protein subunits MLL1 or MLL2 in human, or equivalent in other species. GO:0044666 MLL3/4 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044666 Trr/COMPASS-like complex A protein complex that can methylate lysine-4 of histone H3, and which contains either of the protein subunits MLL3 or MLL4 in mammals, or equivalent in other species. GO:0044663 establishment or maintenance of cell type involved in phenotypic switching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044663 A cellular process of the specification, formation or maintenance of an alternative cell type, occurring as part of the process of phenotypic switching. Phenotypic switching begins with changes in cell morphology and altered gene expression patterns and ends when the morphology of a population of cells has reverted back to the default state, accompanied by altered expression patterns. GO:0005055 laminin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005055 Combining with a laminin, a glycoprotein that constitutes the majority of proteins in the basement membrane, to initiate a change in cell activity. GO:0044664 obsolete reversion of cell type to default state involved in phenotypic switching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044664 OBSOLETE. The cellular process of the reversion of cells to their original cell type, occurring as part of the process of phenotypic switching. Phenotypic switching begins with changes in cell morphology and altered gene expression patterns and ends when the morphology of a population of cells has reverted back to the default state, accompanied by altered expression patterns. GO:0005056 tiggrin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005056 Combining with the extracellular matrix ligand tiggrin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0005053 peroxisome matrix targeting signal-2 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005053 peroxisome targeting signal-2 binding|PTS2 binding|peroxisome targeting signal-2 receptor|PEX7|PTS2 receptor|peroxisomal targeting signal 2 (PTS2) binding Interacting selectively and non-covalently with a type 2 peroxisome targeting signal, a nonapeptide with a broad consensus sequence of (R/K)-(L/V/I)-(XXXXX)-(H/Q)-(L/A/F). GO:0044661 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044661 GO:0005054 obsolete peroxisome integral membrane receptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005054 Pas20p|peroxisome integral membrane receptor OBSOLETE. (Was not defined before being made obsolete). GO:0044662 disruption by virus of host cell membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044662 disruption by organism of host cell membrane|disruption by virus of host cell membrane A process by which a virus has a negative effect on the functioning of a host cellular membrane. GO:0005051 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005051 GO:0044660 viral release by cytolysis via pore formation in host cell membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044660 cytolysis by virus via pore formation in host cell membrane|viral exit by cytolysis via pore formation in host cell membrane The killing by a virus of a cell in its host organism by cytolysis, caused by the formation by the virus of pores in its host cell membrane. GO:0005052 peroxisome matrix targeting signal-1 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005052 peroxisome targeting signal-1 binding|PTS1 binding|PTS1 receptor|peroxisome targeting signal-1 receptor|PEX5|peroxisomal targeting signal 1 (PTS1) binding Interacting selectively and non-covalently with a type 1 peroxisome targeting signal, a tripeptide with the consensus sequence (S/A/C)-(K/R/H)-L. GO:0005061 obsolete aryl hydrocarbon receptor nuclear translocator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005061 aryl hydrocarbon receptor nuclear translocator activity OBSOLETE. (Was not defined before being made obsolete). CHEBI:140559 N-acetyl-alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactose derivative biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140559 GO:0044669 sodium:galactoside symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044669 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sodium(out)+ galactoside(out) = sodium(in) + galactoside(in). CHEBI:139558 1-O-(5,6-epoxyretinoyl)-beta-D-glucuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139558 GO:0044667 (R)-carnitine:4-(trimethylammonio)butanoate antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044667 RHEA:29427 L-carnitine:gamma-butyrobetaine antiporter activity|L-carnitine:4-(trimethylammonio)butanoate antiporter activity|(R)-carnitine:gamma-butyrobetaine antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: (R)-carnitine(out) + 4-(trimethylammonio)butanoate(in) = (R)-carnitine(in) + 4-(trimethylammonio)butanoate(out). CHEBI:139559 (9Z,12R)-12-hydroxyoctadec-9-enoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139559 GO:0044668 sodium:malonate symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044668 RHEA:33135 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sodium(out)+ malonate(out) = sodium(in) + malonate(in). GO:0019698 D-galacturonate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019698 MetaCyc:GALACTUROCAT-PWY D-galacturonate degradation|D-galacturonate breakdown|D-galacturonate catabolism The chemical reactions and pathways resulting in the breakdown of D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid. GO:0030013 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030013 CHEBI:139553 7(1)-hydroxybacteriochlorophyllide d biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139553 GO:0030014 CCR4-NOT complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030014 The Ccr4-Not complex is an eukaryotically conserved deadenylase that can initiate cytoplasmic mRNA decay, and reduce translation by releasing poly(A)-binding protein (Pab1/PABPC1). Ccr4-Not contains seven core subunits, including two poly(A)-specific exonucleases, Ccr4/CNOT6/CNOT6L and Caf1/Pop2/CNOT7/CNOT8. GO:0019699 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019699 GO:0030011 maintenance of cell polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030011 The maintenance of established anisotropic intracellular organization or cell growth patterns. GO:0019696 toluene oxidation via toluene-cis-1,2-dihydrodiol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019696 MetaCyc:TOLUENE-DEG-DIOL-PWY The degradation of toluene to form pyruvate and acetaldehyde; the first step in the pathway is the oxidation of toluene to form toluene-cis-1,2-dihydrodiol. CHEBI:139555 7(1),7(1)-dihydroxybacteriochlorophyllide d biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139555 GO:0019697 L-xylitol catabolic process to xylulose 5-phosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019697 MetaCyc:LARABITOLUTIL-PWY L-xylitol breakdown to xylulose 5-phosphate|L-xylitol utilization|L-xylitol degradation to xylulose 5-phosphate|L-arabitol and xylitol degradation The chemical reactions and pathways resulting in the breakdown of L-xylitol to form xylulose 5-phosphate. L-xylitol is converted into L-xylulose, which is then phosphorylated to L-xylulose-5-phosphate. This is converted to D-xylulose-5-phosphate via the intermediate L-ribulose-5-phosphate. GO:0030012 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030012 CHEBI:139556 EC 4.1.1.17 (ornithine decarboxylase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139556 GO:0019694 alkanesulfonate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019694 MetaCyc:ALKANEMONOX-PWY alkanesulphonate metabolic process|alkanesulfonate metabolism|alkanesulphonate metabolism The chemical reactions and pathways involving alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group. GO:0030010 establishment of cell polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030010 cell polarization|bud site selection/establishment of cell polarity The specification and formation of anisotropic intracellular organization or cell growth patterns. GO:0019695 choline metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019695 choline metabolism The chemical reactions and pathways involving choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine. GO:0019692 deoxyribose phosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019692 deoxyribose phosphate metabolism The chemical reactions and pathways involving deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose. GO:0019693 ribose phosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019693 ribose phosphate metabolism The chemical reactions and pathways involving ribose phosphate, any phosphorylated ribose sugar. GO:0030008 TRAPP complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030008 Wikipedia:TRAPP_complex TRAPP2|TRAPP1|transport protein particle|transport protein particle complex A large complex that acts as a tethering factor involved in transporting vesicles from the ER through the Golgi to the plasma membrane. A TRAPP (transport protein particle) complex has a core set of proteins which are joined by specific subunits depending on the cellular component where a given TRAPP complex is active. GO:0030009 obsolete complement factor H activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030009 complement factor H activity OBSOLETE. A cofactor for the serine protease complement factor I. CHEBI:139570 8-formyl-8-demethylriboflavin 5'-phosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139570 GO:0030006 obsolete heavy cellular metal ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030006 heavy cellular metal ion homeostasis OBSOLETE. Regulation of the levels, transport, and metabolism of ions of a heavy metal, a metal that can form a coordination bond with a protein, as opposed to an alkali or alkaline-earth metal that can only form an ionic bond; this definition includes the following biologically relevant heavy metals: Cd, Co, Cu, Fe, Hg, Mn, Mo, Ni, V, W, Zn. GO:0030007 cellular potassium ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030007 Any process involved in the maintenance of an internal steady state of potassium ions at the level of a cell. GO:0030004 cellular monovalent inorganic cation homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030004 Any process involved in the maintenance of an internal steady state of monovalent inorganic cations at the level of a cell. GO:0030005 obsolete cellular di-, tri-valent inorganic cation homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030005 cellular di-, tri-valent inorganic cation homeostasis OBSOLETE. Any process involved in the maintenance of an internal steady state of divalent or trivalent cations at the level of a cell. GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005068 transmembrane receptor protein tyrosine kinase adaptor protein activity|transmembrane receptor protein tyrosine kinase docking protein activity The binding activity of a molecule that brings together a transmembrane receptor protein tyrosine kinase and one or more other molecules, permitting them to function in a coordinated way. GO:0044676 formyl-methanofuran dehydrogenase (molybdenum enzyme) complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044676 A protein complex consisting of three polypeptides which also contains molybdenum, a molybdopterin guanine dinucleotide and iron-sulfur clusters. This protein complex catalyzes the reversible conversion of CO2 and methanofuran to formylmethanofuran during methanogenesis. GO:0044677 methyl-tetrahydromethanopterin:coenzyme M methyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044677 5-methyl-5,6,7,8-tetrahydromethanopterin:2-mercaptoethane sulfonate 2-methyltransferase complex|N5-methyltetrahydromethanopterin-coenzyme M methyltransferase complex|methyl-H4MPT|coenzyme M methyltransferase complex A protein complex consisted of eight polypeptides. This complex catalyzes the formation of methyl-coenzyme M and H4MPT from N5-methyl-H4MPT and CoM during methanogenesis. GO:0005069 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005069 GO:0044674 methyl coenzyme M reductase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044674 A hexameric complex consisting of three polypeptides in an alpha2beta2gamma2 arrangement. Involved in the reduction of the coenzyme M-bound methyl group to methane, which is the final step in methanogenesis. GO:0005066 obsolete transmembrane receptor protein tyrosine kinase signaling protein activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005066 transmembrane receptor protein tyrosine kinase signaling protein activity|transmembrane receptor protein tyrosine kinase signalling protein activity OBSOLETE. (Was not defined before being made obsolete). GO:0044675 formyl-methanofuran dehydrogenase (tungsten enzyme) complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044675 A protein complex consisting of four polypeptides which also contains tungsten, a molybdopterin guanine dinucleotide, and iron-sulfur clusters. This protein complex catalyzes the reversible conversion of CO2 and methanofuran to formylmethanofuran during methanogenesis. GO:0005067 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005067 GO:0044672 acetyl-CoA decarbonylase/synthase-carbon monoxide dehydrogenase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044672 CO dehydrogenase complex|CODH/ACS complex|carbon-monoxide:(acceptor) oxidoreductase complex|carbon monoxide dehydrogenase|CO dehydrogenase/acetyl-CoA synthase complex|CODH A multifunctional enzyme complex composed of five different polypeptides that catalyzes the decarbonylation of acetyl-CoA, cleaves the C-C and C-S bonds in the acetyl moiety of acetyl-CoA, oxidizes the carbonyl group to CO2 and transfers the methyl group to tetrahydrosarcinapterin. These reactions are important for methanogenesis. GO:0044673 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044673 FO-synthase complex A heterodimer which catalyses the reaction of 5-amino-6-(D-ribitylamino)uracil and 4-hydroxyphenylpyruvate to form 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO), an intermediate of coenzyme F420. GO:0005065 obsolete heterotrimeric G-protein biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005065 heterotrimeric G-protein OBSOLETE. (Was not defined before being made obsolete). GO:0005062 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005062 GO:0044670 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044670 GO:0044671 sorocarp spore cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044671 The process in which a relatively unspecialized cell acquires specialized features of a sorocarp spore cell, a cell of the sorocarp sorus. A sorocarp is the fruiting body characteristic of certain cellular slime moulds (e.g., Dictyosteliida) and consists of both stalk and a sorus (spore mass). GO:0005071 obsolete transmembrane receptor protein serine/threonine kinase signaling protein activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005071 transmembrane receptor protein serine/threonine kinase signaling protein activity|transmembrane receptor protein serine/threonine kinase signalling protein activity OBSOLETE. (Was not defined before being made obsolete). GO:0005072 obsolete transforming growth factor beta receptor, cytoplasmic mediator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005072 TGF-beta receptor, cytoplasmic mediator activity|TGFbeta receptor, cytoplasmic mediator activity OBSOLETE. Activity of any of the molecules that transmit the signal from a TGF-beta receptor through the cytoplasm to the nucleus. GO:0005070 obsolete SH3/SH2 adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005070 SH3/SH2 adaptor protein activity OBSOLETE. Interacting selectively and non-covalently and simultaneously with one or more signal transduction molecules, usually acting as a scaffold to bring these molecules into close proximity either using their own SH2/SH3 domains (e.g. Grb2) or those of their target molecules (e.g. SAM68). CHEBI:139569 8-amino-8-demethylriboflavin 5'-phosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139569 GO:0044678 CoB-CoM heterodisulfide reductase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044678 hydrogen:coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide oxidoreductase complex|coenzyme M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase complex A protein complex that in Methanobacterium thermoautotrophicum is composed of six subunits, and in Methanosarcina barkeri contains is composed of either two subunits or nine subunits. Catalyzes the conversion of coenzyme B, coenzyme M, and methanophenazine to form N-{7-[(2-sulfoethyl)dithio]heptanoyl}-3-O-phospho-L-threonine and dihydromethanophenazine. GO:0044679 methanophenazine reducing hydrogenase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044679 A protein complex which catalyzes the conversion of methanophenazine and hydrogen to form dihydromethanophenazine. This typically consists of three polypeptides. GO:0030002 cellular anion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030002 Any process involved in the maintenance of an internal steady state of anions at the level of a cell. GO:0030003 cellular cation homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030003 Any process involved in the maintenance of an internal steady state of cations at the level of a cell. CHEBI:139565 octadecadienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139565 CHEBI:139567 octadecenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139567 GO:0030001 metal ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030001 heavy metal ion transport|divalent metal ion transport The directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:139561 archaeal dolichyl alpha-D-glucosyl phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139561 CHEBI:139562 archaeal dolichyl beta-D-glucuronosyl-(1->4)-alpha-D-glucosyl phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139562 CHEBI:139563 octadecatrienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139563 GO:0044680 methylthiol:coenzyme M methyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044680 methylthiol coenzyme M methyl transferase complex|methylthiol:coenzyme M methyl transferase complex|methylthiol:CoM methyltransferase complex A protein complex of two polypeptides which catalyzes the transfer of methyl group from methylthiol to coenzyme M during methanogenesis. GO:0019680 L-methylmalonyl-CoA biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019680 MetaCyc:PWY0-43 L-methylmalonyl-CoA anabolism|L-methylmalonyl-CoA synthesis|L-methylmalonyl-CoA formation|L-methylmalonyl-CoA biosynthesis The chemical reactions and pathways resulting in the formation of L-methylmalonyl-CoA, the L-enantiomer of 2-carboxypropanoyl-CoA. GO:0005039 obsolete death receptor-associated factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005039 death receptor-associated factor activity OBSOLETE. (Was not defined before being made obsolete). GO:0005037 obsolete death receptor adaptor protein activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005037 death receptor adaptor protein activity OBSOLETE. (Was not defined before being made obsolete). GO:0005038 obsolete death receptor interacting protein activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005038 death receptor interacting protein activity OBSOLETE. (Was not defined before being made obsolete). GO:0044687 geranylfarnesyl diphosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044687 EC:2.5.1.81|RHEA:25694|MetaCyc:RXN-8813 Catalysis of the reaction: geranylgeranyl diphosphate + isopentenyl diphosphate = (2E,6E,10E,14E)-geranylfarnesyl diphosphate + diphosphate. GO:0005035 death receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005035 apoptosis-activating receptor activity Combining with an extracellular messenger (called a death ligand), and transmitting the signal from one side of the plasma membrane to the other to initiate apoptotic or necrotic cell death. CHEBI:140531 GDP-6-deoxy-alpha-D-altrose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_140531 CHEBI:140532 N-arachidonoyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140532 GO:0044688 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044688 Catalysis of the reaction: 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate + H2O = 7,8-dihydroneopterin 3'-phosphate + H+. GO:0044685 tetrahydromethanopterin-dependent serine hydroxymethyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044685 EC:2.1.2.- Catalysis of the reaction: tetrahydromethanopterin + L-serine = 5,10-methylenetetrahydromethanopterin + glycine + H2O. GO:0005033 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005033 GO:0044686 cysteate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044686 EC:2.5.1.76|RHEA:26486|MetaCyc:RXN-11108 Catalysis of the reaction: L-phosphoserine + SO32- = L-cysteate + HPO4-. GO:0005034 osmosensor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005034 Sensing extracellular osmolarity to initiate a change in cell activity, and spanning the membrane of the cell. GO:0044683 methylthiol:coenzyme M methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044683 RHEA:32667|EC:2.1.1.251|MetaCyc:RXN-8125 methylthiol:coenzyme M methyl transferase activity Catalysis of the overall reaction: methyl-Co(III) methylated-thiol-specific corrinoid protein + coenzyme M = Co(I) methylated--thiol-specific corrinoid protein + methyl-CoM. GO:0005031 tumor necrosis factor-activated receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005031 tumor necrosis factor receptor activity|TNF receptor activity|TNF receptor activity, type I|tumor necrosis factor receptor activity, type II|tumor necrosis factor receptor activity, type I|TNF receptor activity, type II|NGF/TNF (6 C-domain) receptor activity Combining with tumor necrosis factor, a proinflammatory cytokine produced by monocytes and macrophages, to initiate a change in cell function. GO:0044684 dihydromethanopterin reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044684 EC:1.5.99.15|RHEA:42804 Catalysis of the reaction: 7,8-dihydromethanopterin + NADPH = 5,6,7,8-tetrahydromethanopterin + NADP. GO:0005032 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005032 GO:0044681 sulfopyruvate decarboxylase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044681 A complex of two polypeptides which form a dodecamer (A6B6). Catalyzes the decarboxylation of sulfopyruvic acid to sulfoacetaldehyde. This reaction is involved in coenzyme M biosynthesis. GO:0044682 archaeal-specific GTP cyclohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044682 MptA activity|Fe(2+)-dependent archaeal-specific GTP cyclohydrolase activity Catalysis of the reaction: GTP + H2O <=> 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate + diphosphate +formate + H+. This activity is part of the biosynthesis of methanopterin in Archaea, and requires Fe2+. GO:0005030 neurotrophin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005030 Combining with a neurotrophin, any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth, and transmitting the signal to initiate a change in cell activity. CHEBI:139539 (S,S)-bis-(3-oleoylglycero)-1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139539 CHEBI:140537 diethylphosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140537 CHEBI:140535 TRPV1 agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_140535 CHEBI:140533 3-acetamido-4-hydroxybenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140533 GO:0044689 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044689 MetaCyc:RXN-8079|EC:2.5.1.147|RHEA:27373 FO synthase Catalysis of the reaction: 5-amino-6-(D-ribitylamino)uracil + 4-hydroxyphenylpyruvate + 2 S-adenosyl-L-methionine + H2O = 7,8-didemethyl-8-hydroxy-5-deazariboflavin + 2 5'-deoxyadenosine + 2 L-methionine + oxalate + ammonia + 4 H+. GO:0019678 propionate metabolic process, methylmalonyl pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019678 MetaCyc:PROPIONMET-PWY propionate metabolism, methylmalonyl pathway The chemical reactions and pathways involving propionate that occur in the methylmalonyl pathway. CHEBI:140534 3-acetylamino-4-hydroxybenzaldehyde(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140534 GO:0019679 propionate metabolic process, methylcitrate cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019679 MetaCyc:PWY0-42 propionate metabolism, methylcitrate cycle The chemical reactions and pathways involving propionate that occur in the methylcitrate cycle. GO:0019676 ammonia assimilation cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019676 MetaCyc:AMMASSIM-PWY|MetaCyc:PWY-3282 glutamate metabolism via glutamine and ammonia|glutamate metabolic process via glutamine and ammonia The pathway by which ammonia is processed and incorporated into a cell. In an energy-rich (glucose-containing), nitrogen-poor environment, glutamine synthetase and glutamate synthase form an ammonia assimilatory cycle, in which ammonia is incorporated into L-glutamate to form L-glutamine, which then combines with alpha-ketoglutarate to regenerate L-glutamate. This ATP-dependent cycle is essential for nitrogen-limited growth and for steady-state growth with some sources of nitrogen. GO:0019677 NAD catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019677 oxidized NAD catabolic process|NAD (reduced) catabolic process|reduced NAD catabolism|NAD catabolism|reduced nicotinamide adenine dinucleotide catabolism|nicotinamide adenine dinucleotide catabolism|NAD (oxidized) catabolic process|NADH catabolism|NAD degradation|NADH catabolic process|NAD (oxidized) catabolism|nicotinamide adenine dinucleotide catabolic process|NAD breakdown|reduced nicotinamide adenine dinucleotide catabolic process|reduced NAD catabolic process|NAD (reduced) catabolism|oxidized NAD catabolism|oxidized nicotinamide adenine dinucleotide catabolic process|oxidized nicotinamide adenine dinucleotide catabolism The chemical reactions and pathways resulting in the breakdown of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; catabolism may be of either the oxidized form, NAD, or the reduced form, NADH. GO:0019674 NAD metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019674 oxidized nicotinamide adenine dinucleotide metabolism|NAD (oxidized) metabolic process|NAD metabolism|nicotinamide adenine dinucleotide metabolic process|nicotinamide adenine dinucleotide metabolism|NAD (oxidized) metabolism|oxidized nicotinamide adenine dinucleotide metabolic process|oxidized NAD metabolic process|oxidized NAD metabolism|NAD phosphorylation and dephosphorylation The chemical reactions and pathways involving nicotinamide adenine dinucleotide (NAD), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid. GO:0019675 obsolete NAD phosphorylation and dephosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019675 nicotinamide adenine dinucleotide phosphorylation and dephosphorylation|NAD phosphorylation and dephosphorylation OBSOLETE. The addition or removal of a phosphate group from nicotinamide adenine dinucleotide (NAD), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid. GO:0019672 ethanol-acetate fermentation to butyrate and caproate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019672 The anaerobic chemical reactions and pathways resulting in the breakdown of ethanol and acetate to butyrate and caproate, yielding energy in the form of ATP. GO:0019673 GDP-mannose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019673 GDP-mannose metabolism The chemical reactions and pathways involving GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate. GO:0019670 anaerobic glutamate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019670 glutamate fermentation The anaerobic chemical reactions and pathways resulting in the breakdown of glutamate, yielding energy in the form of ATP. GO:0019671 glutamate catabolic process via mesaconate and citramalate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019671 MetaCyc:GLUDEG-II-PWY|MetaCyc:PWY-5088|MetaCyc:PWY-5087 glutamate fermentation via mesaconate and citramalate The anaerobic chemical reactions and pathways resulting in the breakdown of glutamate via the intermediates mesaconate and S-citramalate, yielding energy in the form of ATP. GO:0019690 pyrimidine deoxyribonucleoside interconversion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019690 The chemical reactions and pathways by which a pyrimidine deoxyribonucleoside is synthesized from another deoxyribopyrimidine nucleoside. GO:0044690 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044690 GO:0019691 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019691 GO:0044691 tooth eruption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044691 Wikipedia:Tooth_eruption The tooth development process in which the teeth enter the mouth and become visible. GO:0005048 signal sequence binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005048 signal sequence receptor|protein signal sequence binding|leader sequence binding Interacting selectively and non-covalently with a signal sequence, a specific peptide sequence found on protein precursors or mature proteins that dictates where the mature protein is localized. GO:0005049 nuclear export signal receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005049 NES receptor|importin-alpha binding|exportin activity|importin-alpha export receptor activity Combining with a nuclear export signal (NES) on a cargo to be transported, to mediate transport of a the cargo through the nuclear pore, from the nuclear lumen to the cytoplasm. The cargo can be either a RNA or a protein. GO:0044698 morphogenesis of symbiont in host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044698 The process in which a symbiont undergoes a change in shape or form, within the host's cell. GO:0005046 KDEL sequence binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005046 KDEL receptor activity Interacting selectively and non-covalently with a KDEL sequence, the C terminus tetrapeptide sequence Lys-Asp-Glu-Leu found in proteins that are to be retained in the endoplasmic reticulum. RO:0002022 directly regulated by biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002022 RO:0002022 RO:0002023 directly negatively regulated by biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002023 RO:0002023 Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1. GO:0005047 signal recognition particle binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005047 signal recognition particle receptor|docking protein Interacting selectively and non-covalently with the signal recognition particle. GO:0044699 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044699 CHEBI:140521 13-methyltetradecenal biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_140521 GO:0044696 killing by virus of host cell by post-segregational killing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044696 killing by virus of host cell by PSK|killing by virus of host cell by toxin-antitoxin system The process by which a virus causes the death of daughter cells which do not contain its genes after host cell division, by a mechanism of post-segregational killing (PSK). The extrachromosomal viral DNA consist of two genes; the product of the second is long lived and toxic, while the product of the first is short lived and antagonizes the lethal action of the toxin. Daughter cells that do not contain the viral extrachromosomal element are killed by the long lived toxin, while daughter cells that do contain the viral extrachromosomal element are protected by the action of the short lived antitoxin it encodes. GO:0005044 scavenger receptor activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0005044 macrophage receptor activity Combining with any modified low-density lipoprotein (LDL) or other polyanionic ligand and delivering the ligand into the cell via endocytosis. Ligands include acetylated and oxidized LDL, Gram-positive and Gram-negative bacteria, apoptotic cells, amyloid-beta fibrils, and advanced glycation end products (AGEs). RO:0002024 directly positively regulated by biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002024 RO:0002024 Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1. GO:0044697 HICS complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044697 A multisubunit complex involved in cytokinesis. In the yeast Saccharomyces cerevisiae this complex consists of Sho1p, Hof1p, Inn1p and Cyk3p proteins. GO:0005045 obsolete endoplasmic reticulum receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005045 endoplasmic reticulum receptor activity OBSOLETE. A receptor in the endoplasmic reticulum. RO:0002025 has effector activity biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002025 RO:0002025 A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity. GO:0044694 pore-mediated entry of viral genome into host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044694 VZ:979 viral genome delivery via icosahedral vertex|membrane puncture-mediated penetration of viral genome into host cell|pore-mediated penetration of viral genome into host cell|viral genome translocation|viral pore-forming protein|viral entry via genome injection Injection by a non-enveloped virus of the viral genome into the host cytoplasm through creation of a pore or channel in the host cell membrane(s). Usually mediated by a viral pore-forming peptide associated with the viral capsid or bacteriophage tail. GO:0005042 netrin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005042 Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0005043 netrin receptor activity involved in chemorepulsion biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005043 netrin receptor activity involved in negative chemotaxis|repulsive netrin receptor activity Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to contribute to the directed movement of a motile cell away from a higher concentration of netrin. GO:0044695 Dsc E3 ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044695 An E3 ubiquitin ligase complex localized to the ER and Golgi membrane. In fission yeast comprises Dsc1, 2, 3 and 4. Involved in the processes of fission yeast sre1 (human SREBP) transcriptional activator proteolytic cleavage, the multivesicular body (MVB) pathway, and a post-endoplasmic reticulum pathway for protein catabolism. GO:0044692 exoribonuclease activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044692 Binds to and increases the activity of an exoribonuclease. RO:0002020 transports biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002020 RO:0002020 Holds between p and c when p is a transport process or transporter activity and the outcome of this p is to move c from one location to another. GO:0005040 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005040 GO:0044693 trehalose:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044693 trehalose:hydrogen symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: trehalose(out) + H+(out) = trehalose(in) + H+(in). RO:0002021 occurs across biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002021 RO:0002021 A relationship between a process and a barrier, where the process occurs in a region spanning the barrier. For cellular processes the barrier is typically a membrane. Examples include transport across a membrane and membrane depolarization. GO:0005041 low-density lipoprotein particle receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005041 Reactome:R-HSA-2424254|Reactome:R-HSA-2404131|Wikipedia:LDL_receptor LDL receptor|low-density lipoprotein receptor activity|LDLR activity Combining with a low-density lipoprotein particle and delivering the low-density lipoprotein particle into the cell via endocytosis. RO:0002019 has ligand biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002019 RO:0002019 A relationship that holds between between a receptor and an chemical entity, typically a small molecule or peptide, that carries information between cells or compartments of a cell and which binds the receptor and regulates its effector function. CHEBI:57495 2-aminomuconate 6-semialdehyde(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_57495 CHEBI:140528 6-methylthioguanine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140528 GO:0005050 obsolete peroxisome receptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005050 peroxisome receptor OBSOLETE. (Was not defined before being made obsolete). CHEBI:57496 3-carboxy-cis,cis-muconate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57496 CHEBI:57493 pseudotropinium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57493 CHEBI:140526 1,2-dihexanoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140526 CHEBI:140527 1,2-dihexanoyl-3-oleoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140527 RO:0002015 has positive regulatory component activity biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002015 RO:0002015 A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B. CHEBI:57491 staurosporinium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57491 CHEBI:57492 isopropylaminium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57492 CHEBI:140525 sn-1,2-diricinolein biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140525 RO:0002016 has necessary component activity biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002016 RO:0002016 GO:0019689 pyrimidine nucleoside interconversion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019689 The chemical reactions and pathways by which a pyrimidine nucleoside is synthesized from another pyrimidine nucleoside. CHEBI:140522 [(1->4)-alpha-D-galacturonosyl methyl ester](n) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140522 RO:0002017 has component activity biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002017 RO:0002017 RO:0002018 has component process biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002018 RO:0002018 w 'has process component' p if p and w are processes, w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type. CHEBI:57490 N-carbamoylsarcosinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57490 CHEBI:140523 [(1->4)-alpha-D-galacturonosyl](n) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140523 GO:0019687 pyruvate biosynthetic process from acetate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019687 pyruvate synthesis from acetate|pyruvate anabolism from acetate|pyruvate formation from acetate The chemical reactions and pathways resulting in the formation of pyruvate from other compounds, including acetate. GO:0019688 purine deoxyribonucleoside interconversion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019688 The chemical reactions and pathways by which a purine deoxyribonucleoside is synthesized from another purine deoxyribonucleoside. CHEBI:139543 (S,S)-2-oleoylglycero-1-phospho-1'-glycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139543 GO:0019685 photosynthesis, dark reaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019685 A complex cycle of enzyme-mediated reactions which catalyzes the reduction of carbon dioxide to sugar. As well as carbon dioxide the cycle requires reducing power in the form of reduced nicotinamide adenine dinucleotide phosphate (NADP) and chemical energy in the form of adenosine triphosphate (ATP). The reduced NADP (NADPH) and ATP are produced by the 'light' reactions. GO:0019686 purine nucleoside interconversion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019686 The chemical reactions and pathways by which a purine nucleoside is synthesized from another purine nucleoside. GO:0019683 glyceraldehyde-3-phosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019683 glyceraldehyde-3-phosphate catabolism|glyceraldehyde 3-phosphate catabolic process|glyceraldehyde-3-phosphate degradation|glyceraldehyde-3-phosphate breakdown|glyceraldehyde 3-phosphate catabolism The chemical reactions and pathways resulting in the breakdown of glyceraldehyde-3-phosphate, an important intermediate in glycolysis. CHEBI:57499 2-oxoadipate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57499 GO:0019684 photosynthesis, light reaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019684 MetaCyc:PWY-101|Wikipedia:Photolysis#Photolysis_in_photosynthesis photolysis The light reactions of photosynthesis, which take place in photosystems II and I. Light energy is harvested and used to power the transfer of electrons among a series of electron donors and acceptors. The final electron acceptor is NADP+, which is reduced to NADPH. NADPH generated from light reactions is used in sugar synthesis in dark reactions. Light reactions also generate a proton motive force across the thylakoid membrane, and the proton gradient is used to synthesize ATP. There are two chemical reactions involved in the light reactions: water oxidation in photosystem II, and NADP reduction in photosystem I. CHEBI:139540 (S,S)-3-oleoylglycero-1-phospho-1'-glycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139540 CHEBI:57497 dolichyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57497 GO:0019681 acetyl-CoA assimilation pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019681 acetyl-CoA catabolic process to alpha-ketoglutarate|acetyl-CoA catabolism to 2-ketoglutarate|acetyl-CoA catabolic process to 2-oxoglutarate|acetyl-CoA catabolic process to 2-ketoglutarate|acetyl-CoA catabolism to 2-oxoglutarate|acetyl-CoA catabolic process to alpha-oxoglutarate|acetyl-CoA catabolism to alpha-ketoglutarate|acetyl-CoA catabolism to alpha-oxoglutarate The pathways by which acetyl-CoA is processed and converted into alpha-ketoglutarate (2-oxoglutarate); methanogenic archaea use these pathways to assimilate acetyl-CoA into the cell. GO:0019682 glyceraldehyde-3-phosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019682 glyceraldehyde 3-phosphate metabolism|glyceraldehyde 3-phosphate metabolic process|glyceraldehyde-3-phosphate metabolism The chemical reactions and pathways involving glyceraldehyde-3-phosphate, an important intermediate in glycolysis. CHEBI:57498 ADP alpha-D-glucoside(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57498 CHEBI:139541 (S,S)-bis(2-oleoylglycero)-1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139541 GO:0005019 platelet-derived growth factor beta-receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005019 PDGF beta-receptor activity|betaPDGF receptor activity Combining with platelet-derived growth factor isoform PDGF-BB or PDGF-AB to initiate a change in cell activity. GO:0005017 platelet-derived growth factor-activated receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005017 platelet-derived growth factor receptor activity|PDGFR activity|PDGF-activated receptor activity|PDGF receptor activity Combining with platelet-derived growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity. GO:0005018 platelet-derived growth factor alpha-receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005018 PDGF alpha-receptor activity|alphaPDGF receptor activity Combining with platelet-derived growth factor isoform PDGF-AA, PDGF-BB or PDGF-AB to initiate a change in cell activity. GO:0005015 obsolete neurotrophin TRKB receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005015 neurotrophin TRKB receptor activity OBSOLETE. (Was not defined before being made obsolete). GO:0005016 obsolete neurotrophin TRKC receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005016 neurotrophin TRKC receptor activity OBSOLETE. (Was not defined before being made obsolete). GO:0005013 obsolete neurotrophin TRK receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005013 neurotrophin TRK receptor activity OBSOLETE. (Was not defined before being made obsolete). RO:0002011 regulates transport of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002011 RO:0002011 A relationship that holds between a process that regulates a transport process and the entity transported by that process. GO:0005014 obsolete neurotrophin TRKA receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005014 neurotrophin TRKA receptor activity OBSOLETE. (Was not defined before being made obsolete). GO:0005011 macrophage colony-stimulating factor receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005011 Fms|macrophage colony stimulating factor receptor activity|CSF-1|M-CSF receptor activity Combining with macrophage colony-stimulating factor (M-CSF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate. RO:0002013 has regulatory component activity biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002013 RO:0002013 A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B. RO:0002014 has negative regulatory component activity biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002014 RO:0002014 A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B. GO:0005012 obsolete Neu/ErbB-2 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005012 Neu/ErbB-2 receptor activity OBSOLETE. (Was not defined before being made obsolete). GO:0005010 insulin-like growth factor-activated receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005010 IGF-activated receptor activity|IGF receptor activity|insulin-like growth factor receptor activity Combining with insulin-like growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity. RO:0002008 coincident with biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002008 RO:0002008 A relation that holds between two linear structures that are approximately parallel to each other for their entire length and where either the two structures are adjacent to each other or one is part of the other. CHEBI:57484 trimethylenediaminium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57484 CHEBI:57485 carnosine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57485 CHEBI:139518 (5R)-5,6-dihydro-5-(thymidin-7-yl)thymidine dimer(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139518 CHEBI:57482 streptomycin 3''-phosphate(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57482 CHEBI:140515 6-chloro-D-tryptophan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_140515 CHEBI:139519 thymidine dimer(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139519 CHEBI:140516 6-chlorotryptophan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_140516 CHEBI:57483 sedoheptulose 7-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57483 GO:0019658 glucose fermentation to lactate and acetate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019658 MetaCyc:P124-PWY bifidum pathway|glucose catabolic process to lactate and acetate The anaerobic chemical reactions and pathways resulting in the breakdown of glucose to lactate and acetate, yielding energy in the form of ATP. CHEBI:57480 2,3-dihydrobiochanin A(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_57480 CHEBI:139513 N(4)-{beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-[beta-D-GlcNAc-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-Asn residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139513 GO:0019659 glucose catabolic process to lactate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019659 Wikipedia:Lactic_acid_fermentation lactate fermentation|glucose fermentation to lactate The anaerobic enzymatic chemical reactions and pathways resulting in the breakdown of glucose to lactate, and possibly ethanol, yielding energy in the form of adenosine triphosphate (ATP). RO:0002005 innervated_by biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002005 RO:0002005 nerve supply CHEBI:57481 UTP(3-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_57481 CHEBI:139514 nonaflavuxanthin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139514 GO:0019656 glucose catabolic process to D-lactate and ethanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019656 MetaCyc:P122-PWY heterolactate fermentation|glucose fermentation to D-lactate and ethanol|heterolactic fermentation|heterofermentative lactate fermentation|heterofermentation|heterofermentative pathway The anaerobic chemical reactions and pathways resulting in the enzymatic breakdown of D-glucose to D-lactate and ethanol, yielding energy in the form of adenosine triphosphate (ATP) at the rate of one ATP per glucose molecule. CHEBI:139515 flavuxanthin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139515 RO:0002007 bounding layer of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002007 RO:0002007 X outer_layer_of Y iff: . X :continuant that bearer_of some PATO:laminar . X part_of Y . exists Z :surface . X has_boundary Z . Z boundary_of Y has_boundary: http://purl.obolibrary.org/obo/RO_0002002 boundary_of: http://purl.obolibrary.org/obo/RO_0002000 GO:0019657 glycolytic fermentation to propionate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019657 MetaCyc:P108-PWY succinate-propionate fermentation Glycolytic fermentation resulting in the catabolism of glucose to propionate, yielding energy in the form of ATP; an alternative to the acrylate pathway to produce propionate. GO:0019654 acetate fermentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019654 MetaCyc:P142-PWY The anaerobic chemical reactions and pathways resulting in the breakdown of acetate, yielding energy in the form of ATP. GO:0019655 glycolytic fermentation to ethanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019655 Wikipedia:Ethanol_fermentation alcoholic fermentation|ethanol fermentation|glucose catabolic process to ethanol|glucose fermentation to ethanol The anaerobic chemical reactions and pathways resulting in the breakdown of glucose; it is converted into ethanol and carbon dioxide (CO2), producing two molecules of ATP for each molecule of glucose. CHEBI:139510 N(4)-{beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-Asn residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139510 GO:0019652 lactate fermentation to propionate and acetate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019652 MetaCyc:PROPFERM-PWY acrylate pathway|propionate fermentation|nonrandomizing pathway The anaerobic enzymatic conversion of lactate to propionate, concomitant with the oxidation of lactate to acetate and CO2 and yielding energy in the form of adenosine triphosphate (ATP). CHEBI:139511 reduced coenzyme F420-(gamma-Glu)n polyanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139511 GO:0019653 anaerobic purine nucleobase catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019653 MetaCyc:P164-PWY|MetaCyc:PWY-5497|MetaCyc:PWY-5044 anaerobic purine base catabolism|anaerobic purine catabolic process|purine fermentation|anaerobic purine base catabolic process|purine base fermentation The anaerobic chemical reactions and pathways resulting in the breakdown of purine nucleobases, yielding energy in the form of ATP. GO:0019650 glycolytic fermentation to butanediol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019650 MetaCyc:P125-PWY|Wikipedia:Butanediol_fermentation glucose catabolic process to butanediol|glucose fermentation to butanediol|butanediol fermentation The anaerobic chemical reactions and pathways resulting in the breakdown of glucose into butanediol; effected by some members of the Enterobacteriaceae, e.g. Enterobacter, Erwinia, Klebsiella, and Serratia. CHEBI:57488 hydrogen phosphonatoacetate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57488 GO:0019651 citrate catabolic process to diacetyl biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019651 diacetyl fermentation|citrate fermentation to diacetyl The anaerobic chemical reactions and pathways resulting in the breakdown of citrate to diacetyl, yielding energy in the form of ATP. CHEBI:57486 4-guanidinobutanoic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57486 CHEBI:57487 pyruvate oxime biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57487 GO:0005028 obsolete CD40 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005028 CD40 receptor activity OBSOLETE. (Was not defined before being made obsolete). GO:0005029 obsolete CD27 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005029 CD27 receptor activity OBSOLETE. (Was not defined before being made obsolete). GO:0005026 transforming growth factor beta receptor activity, type II biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005026 Reactome:R-HSA-170843 type II TGFbeta receptor activity|type II TGF-beta receptor activity|transforming growth factor beta ligand binding to type II receptor|type II transforming growth factor beta receptor activity Combining with transforming growth factor beta to initiate a change in cell activity; upon ligand binding, binds to and catalyzes the phosphorylation of a type I TGF-beta receptor. GO:0005027 obsolete NGF/TNF (6 C-domain) receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005027 NGF/TNF (6 C-domain) receptor activity OBSOLETE. (Was not defined before being made obsolete). GO:0005024 transforming growth factor beta-activated receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005024 TGF-beta receptor activity|TGFbeta-activated receptor activity|TGFbeta receptor activity|TGFbetaR|transforming growth factor beta receptor activity Combining with a transforming growth factor beta (TGFbeta) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. GO:0005025 transforming growth factor beta receptor activity, type I biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005025 type I TGF-beta receptor activity|type I TGFbeta receptor activity|transforming growth factor beta ligand binding to type I receptor|type I transforming growth factor beta receptor activity Combining with a complex of transforming growth factor beta and a type II TGF-beta receptor to initiate a change in cell activity; upon binding, acts as a downstream transducer of TGF-beta signals. RO:0002002 has boundary biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002002 RO:0002002 GO:0005023 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005023 GO:0005020 stem cell factor receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005020 KL receptor activity|KIT|KIT ligand receptor activity|SCF receptor activity Combining with stem cell factor (SCF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate. Stem cell factor is a cytokine that stimulates mast cell growth and differentiation. GO:0005021 vascular endothelial growth factor-activated receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005021 VEGF-D-activated receptor activity|VEGF-C-activated receptor activity|VEGF receptor activity|VEGF-B-activated receptor activity|VEGF-A-activated receptor activity|vascular endothelial growth factor E-activated receptor activity|VEGFR activity|VEGF-activated receptor activity|vascular endothelial growth factor receptor activity|VEGF-E-activated receptor activity Combining with a vascular endothelial growth factor (VEGF) and transmitting the signal across the plasma membrane to initiate a change in cell activity. CHEBI:57473 3'-demethylstaurosporinium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57473 CHEBI:57474 (R)-S-lactoylglutathionate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57474 CHEBI:139529 inositol phosphomannosylinositol-1-phospho-N-acylphytosphingosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139529 CHEBI:57471 (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57471 CHEBI:57472 (N(omega)-L-arginino)succinate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57472 GO:0019669 anaerobic glycine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019669 glycine fermentation The anaerobic chemical reactions and pathways resulting in the breakdown of glycine, yielding energy in the form of ATP. CHEBI:57470 (2E)-3-(methoxycarbonyl)pent-2-enedioate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57470 GO:0019667 anaerobic L-alanine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019667 L-alanine fermentation The anaerobic chemical reactions and pathways resulting in the breakdown of L-alanine, yielding energy in the form of ATP. GO:0019668 anaerobic catabolism of pairs of amino acids biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019668 Stickland reaction|cofermentation of pairs of amino acids The anaerobic chemical reactions and pathways resulting in the breakdown of amino acids; in these reactions, one amino acid is oxidised (acts as an electron donor) and a different amino acid is reduced (acts as an electron acceptor); oxidation of the electron-donating amino acid yields energy in the form of ATP. GO:0019665 anaerobic amino acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019665 amino acid fermentation The anaerobic chemical reactions and pathways resulting in the breakdown of amino acids, yielding energy in the form of ATP. CHEBI:139520 phenolic donor biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139520 GO:0019666 nitrogenous compound fermentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019666 nitrogenous compound catabolic process The anaerobic chemical reactions and pathways resulting in the breakdown of a nitrogen-containing compound, yielding energy in the form of ATP. CHEBI:139521 phenolic radical donor biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139521 GO:0019663 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019663 CHEBI:57479 2,6-dioxo-6-phenylhexanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57479 GO:0019664 mixed acid fermentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019664 Wikipedia:Mixed_acid_fermentation glucose catabolic process to mixed acids|glucose fermentation to mixed acids The anaerobic chemical reactions and pathways resulting in the breakdown of glucose into ethanol, lactate, formate, succinate, and acetate, yielding energy in the form of ATP. GO:0019661 glucose catabolic process to lactate via pyruvate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019661 MetaCyc:ANAEROFRUCAT-PWY homofermentation|glucose fermentation to lactate via pyruvate|homolactic fermentation|homofermentative pathway|homolactate fermentation|homofermentative lactate fermentation The anaerobic enzymatic chemical reactions and pathways resulting in the breakdown of glucose to lactate, via canonical glycolysis, yielding energy in the form of adenosine triphosphate (ATP). CHEBI:57477 dTDP-alpha-D-glucose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57477 GO:0019662 non-glycolytic fermentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019662 Fermentation that does not include the anaerobic conversion of glucose to pyruvate via the glycolytic pathway. CHEBI:57478 alpha-maltose 6'-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57478 CHEBI:57475 D-4-hydroxyphenylglycine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57475 CHEBI:57476 L-homoserine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57476 GO:0019660 glycolytic fermentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019660 MetaCyc:Pyruvate-Degredation Fermentation that includes the anaerobic conversion of glucose to pyruvate via the glycolytic pathway. CHEBI:140509 6-chloro-D-tryptophan zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140509 CHEBI:57462 leukotriene E4(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57462 CHEBI:57463 leukotriene A4(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57463 CHEBI:57460 20-hydroxy-leukotriene B4(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57460 CHEBI:33497 transition element molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33497 GO:0019638 6-hydroxycineole metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019638 6-endo-hydroxycineole metabolic process|hydroxycineol metabolism|6-hydroxycineole metabolism|hydroxycineol metabolic process|6-endo-hydroxycineole metabolism The chemical reactions and pathways involving 6-hydroxycineole (6-hydroxy-1,8-epoxy-p-menthane), a hydrocarbon with the formula C10H18O2. GO:0019639 6-hydroxycineole catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019639 MetaCyc:6-HYDROXYCINEOLE-DEGRADATION-PWY hydroxycineol catabolic process|hydroxycineol catabolism|6-hydroxycineole catabolism|6-endo-hydroxycineole catabolic process|6-hydroxycineole degradation|6-endo-hydroxycineole catabolism|6-hydroxycineole breakdown The chemical reactions and pathways resulting in the breakdown of 6-hydroxycineole (6-hydroxy-1,8-epoxy-p-menthane), a hydrocarbon with the formula C10H18O2. CHEBI:57461 leukotriene B4(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57461 GO:0019636 phosphonoacetate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019636 MetaCyc:P483-PWY phosphonoacetate metabolism The chemical reactions and pathways involving phosphonoacetate, C2H4PO5, a substance composed of an acetate and a phosphonic acid residue. GO:0019637 organophosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019637 organophosphate metabolism The chemical reactions and pathways involving organophosphates, any phosphate-containing organic compound. GO:0019634 organic phosphonate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019634 organophosphonate metabolic process|phosphonate metabolism The chemical reactions and pathways involving phosphonates, any organic compounds containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Metabolism of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included. GO:0019635 2-aminoethylphosphonate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019635 MetaCyc:PHOSPHONOTASE-PWY ciliatine catabolic process|2-phosphonoethylamine catabolic process|2-phosphonoethylamine catabolism|ciliatine catabolism|2-aminoethylphosphonate degradation|2-aminoethylphosphonate catabolism|2-aminoethylphosphonate breakdown The chemical reactions and pathways resulting in the breakdown of 2-aminoethylphosphonate, also known as ciliatine. GO:0019632 shikimate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019632 shikimate metabolism The chemical reactions and pathways involving shikimate, (3R,4S,5R)--3,4,5-trihydroxycyclohex-1-ene-1-carboxylate, the anion of shikimic acid. It is an important intermediate in the biosynthesis of aromatic amino acids. GO:0019633 shikimate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019633 MetaCyc:SHIKIMATEDEG-PWY shikimate degradation|shikimate catabolism|shikimate breakdown The chemical reactions and pathways resulting in the breakdown of shikimate, (3R,4S,5R)--3,4,5-trihydroxycyclohex-1-ene-1-carboxylate, the anion of shikimic acid. CHEBI:57468 7(S),8(S)-DiHODE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57468 GO:0019630 quinate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019630 quinate metabolism|quinic acid metabolic process|quinic acid metabolism The chemical reactions and pathways involving quinate, the anion of quinic acid. The acid occurs commonly in plants, either free or as esters, and is used as a medicine. GO:0019631 quinate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019631 MetaCyc:QUINATEDEG-PWY quinate catabolism|quinic acid catabolic process|quinic acid catabolism|quinate degradation|quinate breakdown The chemical reactions and pathways resulting in the breakdown of quinate, the anion of quinic acid. CHEBI:57469 (2E)-2-(methoxycarbonylmethyl)but-2-enedioate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57469 CHEBI:33490 hydrogenselenate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33490 CHEBI:57466 13(S)-HPODE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57466 CHEBI:57467 (11S)-11-hydroperoxylinoleate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57467 CHEBI:57464 5'-xanthylate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57464 GO:0005008 hepatocyte growth factor-activated receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005008 HGF-activated receptor activity|HGF receptor activity|hepatocyte growth factor receptor activity Combining with hepatocyte growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity. GO:0005009 insulin-activated receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005009 insulin receptor activity Combining with insulin and transmitting the signal across the plasma membrane to initiate a change in cell activity. GO:0005006 epidermal growth factor-activated receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005006 epidermal growth factor receptor activity|transforming growth factor-alpha receptor activity|TGF-alpha receptor activity|EGF receptor activity|EGFR Combining with an epidermal growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity. GO:0005007 fibroblast growth factor-activated receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005007 FGF-activated receptor activity|fibroblast growth factor receptor activity|FGF receptor activity|FGFR Combining with a fibroblast growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity. GO:0005004 GPI-linked ephrin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005004 GPI-linked Eph receptor activity Combining with a GPI-anchored ephrin to initiate a change in cell activity. GO:0005005 transmembrane-ephrin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005005 transmembrane-Eph receptor activity Combining with a transmembrane ephrin to initiate a change in cell activity. GO:0005003 ephrin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005003 Eph receptor activity Combining with an ephrin to initiate a change in cell activity. GO:0005000 vasopressin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005000 vasopressin activated calcium mobilizing receptor activity Combining with vasopressin to initiate a change in cell activity. GO:0005001 transmembrane receptor protein tyrosine phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005001 Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate. CHEBI:57451 dihydrofolate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57451 CHEBI:139506 N(5)-phospho-L-glutamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139506 CHEBI:139507 N(4)-{beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-Asn residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139507 CHEBI:57452 10-formyldihydrofolate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57452 GO:0019649 formaldehyde assimilation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019649 The pathways in which formaldehyde is processed and used as a carbon source for the cell. CHEBI:139508 beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-glucosaminide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139508 CHEBI:57450 5(S)-HPETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57450 CHEBI:139509 alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-glucosaminide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139509 GO:0019647 formaldehyde assimilation via ribulose monophosphate cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019647 MetaCyc:PWY-1861 ribulose monophosphate cycle|formaldehyde assimilation via RuMP cycle The pathway in which formaldehyde is used as a carbon source in the ribulose monophosphate cycle. Methanotrophic bacteria produce formaldehyde from the oxidation of methane and methanol, and then assimilate it via the ribulose monophosphate cycle to form intermediates of the central metabolic routes that are subsequently used for biosynthesis of cell material. Three molecules of formaldehyde are assimilated, forming a three-carbon intermediate of central metabolism; in this pathway, all cellular carbon is assimilated at the oxidation level of formaldehyde. GO:0019648 formaldehyde assimilation via xylulose monophosphate cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019648 MetaCyc:P185-PWY formaldehyde assimilation via xylulose-5-phosphate cycle|formaldehyde fixation cycle The pathway in which formaldehyde is used as a carbon source in the xylulose monophosphate cycle. Methylotrophic yeasts, but not bacteria, utilize the xylulose monophosphate cycle to fix formaldehyde and convert it into metabolically useful organic compounds. CHEBI:139504 N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->4)]-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-Asn residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139504 GO:0019645 anaerobic electron transport chain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019645 A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors other than oxygen to generate a transmembrane electrochemical gradient. GO:0019646 aerobic electron transport chain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019646 NADH-O2 electron transport|ubiquinone-8-O2 electron transport|succinate-O2 electron transport A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to oxygen to generate a transmembrane electrochemical gradient. CHEBI:139505 baeocystin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139505 GO:0019643 reductive tricarboxylic acid cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019643 MetaCyc:P23-PWY|MetaCyc:REDCITCYC reductive Kreb's cycle|reductive carboxylate cycle|reductive citric acid pathway|reductive carboxylic acid cycle|reductive TCA cycle A pathway leading to the fixation of two molecules of CO2 and the production of one molecule of acetyl-CoA; essentially the oxidative TCA cycle running in reverse. Acetyl-CoA is reductively carboxylated to pyruvate, from which all other central metabolites can be formed. Most of the enzymes of reductive and oxidative TCA cycle are shared, with the exception of three key enzymes that allow the cycle to run in reverse: ATP citrate lyase, 2-oxoglutarate:ferredoxin oxidoreductase, and fumarate reductase. 2-oxoglutarate:ferredoxin oxidoreductase catalyzes the carboxylation of succinyl-CoA to 2-oxoglutarate, ATP citrate lyase the ATP-dependent cleavage of citrate to acetyl-CoA and oxaloacetate, and fumarate reductase the reduction of fumarate forming succinate. CHEBI:57459 (6S)-6-hydroxyhyoscyaminium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57459 GO:0019644 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019644 CHEBI:139500 N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-Asn residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139500 CHEBI:57457 (6S)-5-formyltetrahydrofolate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57457 GO:0019641 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019641 GO:0019642 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019642 CHEBI:57458 (S)-NADHX(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_57458 CHEBI:57455 (6R)-5,10-methenyltetrahydrofolate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57455 GO:0019640 glucuronate catabolic process to xylulose 5-phosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019640 glucuronate degradation to xylulose 5-phosphate|glucuronate breakdown to xylulose 5-phosphate The chemical reactions and pathways resulting in the breakdown of glucuronate into other compounds, including xylulose 5-phosphate. CHEBI:57456 5-formimidoyltetrahydrofolate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57456 CHEBI:57453 (6S)-5,6,7,8-tetrahydrofolate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57453 CHEBI:57454 10-formyltetrahydrofolate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57454 GO:0030093 chloroplast photosystem I biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030093 Photosystem located in the chloroplast that functions as a light-dependent plastocyanin-ferredoxin oxidoreductase, transferring electrons from plastocyanin to ferredoxin. An example of this is found in Arabidopsis thaliana. GO:0030094 plasma membrane-derived photosystem I biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030094 plasma membrane photosystem I A protein complex located in the plasma membrane-derived thylakoid. The photosystem functions as a light-dependent plastocyanin-ferredoxin oxidoreductase, transferring electrons from plastocyanin to ferredoxin. Examples of this complex are found in bacterial species. GO:0030091 protein repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030091 The process of restoring a protein to its original state after damage by such things as oxidation or spontaneous decomposition of residues. GO:0030092 obsolete regulation of flagellum assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030092 regulation of flagellum assembly|regulation of flagella assembly|regulation of flagella biogenesis|regulation of flagellum biogenesis OBSOLETE. Any process that modulates the frequency, rate or extent of the formation of a flagellum. GO:0030090 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030090 GO:0030099 myeloid cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030099 The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages. GO:0030097 hemopoiesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030097 Wikipedia:Haematopoiesis blood cell biosynthesis|blood cell formation|hematopoiesis|haemopoiesis The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates. GO:0030098 lymphocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030098 lymphocytic blood cell differentiation|lymphocyte cell differentiation|lymphocyte development The process in which a relatively unspecialized precursor cell acquires specialized features of a lymphocyte. A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin. GO:0030095 chloroplast photosystem II biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030095 An integral chloroplast membrane complex containing the P680 reaction center. In the light, PSII functions as a water-plastoquinone oxidoreductase, transferring electrons from water to plastoquinone. GO:0030096 plasma membrane-derived thylakoid photosystem II biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030096 plasma membrane photosystem II A protein complex, located in the membrane-derived thylakoid, containing the P680 reaction center. In the light, PSII functions as a water-plastoquinone oxidoreductase, transferring electrons from water to plastoquinone. GO:0030082 B800-850 antenna complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030082 light harvesting complex II|LH2 complex Protein-pigment complex that absorbs light at 800 and 850 nm; is peripherally associated to the bacterial reaction center; transfers excitation energy to the B875 antenna complex. GO:0030083 PSI associated light-harvesting complex I, LHCIa subcomplex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030083 A pigment protein complex that forms part of the photosystem I associated light-harvesting complex I; contains two proteins (usually about 24 and 21.5 kDa); has a fluorescence maximum between 680 and 690 nm. GO:0030080 B875 antenna complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030080 LH1 complex|light harvesting complex I Protein complex that surrounds and transfers excitation energy directly to the bacterial reaction center; binds bacteriochlorophyll a and has a single absorption band between 870 and 890 nm. GO:0030081 B800-820 antenna complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030081 LH3 complex|light harvesting complex III Protein-pigment complex that absorbs light at 800 and 820 nm; is peripherally associated to the bacterial reaction center; transfers excitation energy to the B875 antenna complex. GO:0030088 obsolete PSII associated light-harvesting complex II, core complex, LHCIId subcomplex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030088 PSII associated light-harvesting complex II, core complex, LHCIId subcomplex OBSOLETE. (Was not defined before being made obsolete). GO:0030089 phycobilisome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030089 Wikipedia:Phycobilisome Any of the granules, approximately 32 nm x 48 nm and consisting of highly aggregated phycobiliproteins, that are attached in arrays to the external face of a thylakoid membrane in algae of the phyla Cyanophyta and Rhodophyta, where they function as light-harvesting devices in photosynthesis. Excitation energy in the phycobilisome flows in the sequence: phycoerythrin, phycocyanin, allophycocyanin before passing to the antenna chlorophyll of photosystem II. GO:0030086 obsolete PSII associated light-harvesting complex II, core complex, LHCIIa subcomplex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030086 PSII associated light-harvesting complex II, core complex, LHCIIa subcomplex OBSOLETE. (Was not defined before being made obsolete). GO:0030087 obsolete PSII associated light-harvesting complex II, core complex, LHCIIc subcomplex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030087 PSII associated light-harvesting complex II, core complex, LHCIIc subcomplex OBSOLETE. (Was not defined before being made obsolete). GO:0030084 PSI associated light-harvesting complex I, LHCIb subcomplex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030084 A pigment protein complex that forms part of the photosystem I associated light-harvesting complex I; contains two proteins (usually about 20 kDa); has a fluorescence maximum of 730 nm. GO:0030085 PSII associated light-harvesting complex II, peripheral complex, LHCIIb subcomplex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030085 A pigment protein complex that forms part of the photosystem II associated light-harvesting complex II; contains two proteins (usually about 28 and 27 kDa), and may contain a third; peripherally located relative to other LHC polypeptides. GO:0044600 protein guanylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044600 Catalysis of the reaction: GTP + protein = diphosphate + guanylyl-protein; mediates the addition of an guanylyl (guanosine 5'-monophosphate; GMP group) to specific residues of target proteins. GO:0044607 obsolete disruption by symbiont of host endothelial cells biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044607 OBSOLETE. Any process in which an organism has a negative effect on the functioning of the host's endothelial cells. GO:0030071 regulation of mitotic metaphase/anaphase transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030071 Any process that modulates the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin. GO:0030072 peptide hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030072 The regulated release of a peptide hormone from a cell. GO:0044608 peptidyl-L-threonine methyl ester biosynthetic process from peptidyl-threonine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044608 RESID:AA0507 peptidyl-threonine esterification The modification of a C-terminal peptidyl-threonine to form peptidyl-L-threonine methyl ester. GO:0044605 phosphocholine transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044605 Catalysis of the reaction: CDP-choline + protein-serine = CMP + protein-serine-choline phosphate. GO:0044606 phosphocholine hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044606 Catalysis of the reaction: protein-serine-choline phosphate + H2O = protein-serine + choline phosphate. GO:0030070 insulin processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030070 The formation of mature insulin by proteolysis of the precursor preproinsulin. The signal sequence is first cleaved from preproinsulin to form proinsulin; proinsulin is then cleaved to release the C peptide, leaving the A and B chains of mature insulin linked by disulfide bridges. GO:0044603 protein adenylylhydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044603 protein deAMPylase activity|protein deAMPylation activity Catalysis of the reaction: adenylyl-protein+ H2O = adenylate + protein; mediates the removal of an adenylyl (adenosine 5'-monophosphate; AMP group) from specific residues of target proteins. GO:0044604 ABC-type phytochelatin transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044604 ABC-type phytochelatin transmembrane transporter activity|phytochelatin transmembrane transporter activity|phytochelatin transporter activity|cadystin transmembrane transporter activity|ATPase-coupled phytochelatin transmembrane transporter activity|cadystin transmembrane transporter ATPase activity|ATP-dependent phytochelatin transmembrane transporter activity|cadystin transporter activity|phytochelatin transmembrane transporter ATPase activity Enables the directed movement of a phytochelatin from one side of a membrane to the other. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. GO:0044601 protein denucleotidylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044601 The removal of a nucleotide from a protein amino acid. GO:0044602 protein deadenylylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044602 protein deAMPylation The removal of an adenylyl group (adenosine 5'-monophosphate; AMP) from a protein amino acid. GO:0030079 light-harvesting complex, peripheral complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030079 Bacteriochlorophyll a binding complex that is peripherally associated to the bacterial reaction center. GO:0030077 plasma membrane light-harvesting complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030077 A plasma membrane protein-pigment complex that may be closely or peripherally associated to photosynthetic reaction centers that participate in harvesting and transferring radiant energy to the reaction center. Examples of this complex are found in bacterial species. GO:0030078 light-harvesting complex, core complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030078 Light harvesting complex associated with the reaction complex of photosynthetic purple bacteria. GO:0030075 bacterial thylakoid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030075 plasma membrane-derived thylakoid A thylakoid that is derived from and attached to, but not necessarily continuous with, the plasma membrane, and is not enclosed in a plastid. It bears the photosynthetic pigments in photosynthetic cyanobacteria. GO:0030076 light-harvesting complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0030076 Wikipedia:Light-harvesting_complex antenna complex A protein-pigment complex that may be closely or peripherally associated to photosynthetic reaction centers that participate in harvesting and transferring radiant energy to the reaction center. GO:0044609 DBIRD complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044609 A protein complex that associates with mRNP particles and RNA polymerase II and is proposed to integrate transcript elongation with the regulation of alternative splicing. In humans it is composed of the proteins KIAA1967/DBC1 and ZNF326/ZIRD. GO:0030073 insulin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030073 The regulated release of proinsulin from secretory granules accompanied by cleavage of proinsulin to form mature insulin. In vertebrates, insulin is secreted from B granules in the B cells of the vertebrate pancreas and from insulin-producing cells in insects. GO:0030074 obsolete thylakoid (sensu Proteobacteria) biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030074 thylakoid (sensu Proteobacteria) OBSOLETE. A thylakoid; as in, but not restricted to, the purple bacteria and relatives (Proteobacteria, ncbi_taxonomy_id:1224). UBERON:0004190 renal glomerulus vasculature biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004190 glomerulus vasculature|renal glomerulus vasculature|vascular network of renal glomerulus|renal glomerulus vascular network|vasculature of renal glomerulus The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus GO:0044610 FMN transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044610 flavine mononucleotide transmembrane transporter activity Enables the directed movement of flavine mononucleotide (FMN) from one side of a membrane to the other. GO:0044611 nuclear pore inner ring biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044611 Nup170 complex A subcomplex of the nuclear pore complex (NPC) that forms the inner rings of the core scaffold, a lattice-like structure that gives the NPC its shape and strength. In S. cerevisiae, the two inner rings are each composed of Nup192p, Nup188p, Nup170p and Nup157p. In vertebrates, the two inner rings are each composed of Nup205, Nup188 and Nup155. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometimes referred to as the Nup170 complex. GO:0030060 L-malate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030060 Reactome:R-HSA-70979|EC:1.1.1.37|RHEA:21432|Reactome:R-HSA-71783|MetaCyc:MALATE-DEH-RXN|Reactome:R-HSA-198508 L-malate-NAD+ oxidoreductase activity|NAD-dependent malic dehydrogenase activity|(S)-malate:NAD+ oxidoreductase activity|NAD-malate dehydrogenase activity|NAD-malic dehydrogenase activity|NAD-dependent malate dehydrogenase activity|malate (NAD) dehydrogenase activity|NAD-linked malate dehydrogenase activity|malic acid dehydrogenase activity|MDH|NAD-specific malate dehydrogenase activity|NAD-L-malate dehydrogenase activity|malic dehydrogenase activity Catalysis of the reaction: (S)-malate + NAD+ = oxaloacetate + NADH + H+. GO:0044618 modulation of relaxation of uterine smooth muscle in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044618 regulation of relaxation of uterine smooth muscle in other organism The process in which an organism effects a change in the relaxation of smooth muscle in the uterus of a second organism. UBERON:0004198 comma-shaped body biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004198 CSB The comma-shaped body is the precursor structure to the S-shaped body that contributes to the morphogenesis of the nephron GO:0044619 positive regulation of relaxation of uterine smooth muscle in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044619 The process in which an organism increases the extent of relaxation of smooth muscle in the uterus of a second organism. GO:0030061 mitochondrial crista biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030061 NIF_Subcellular:sao333328131 cristae|mitochondrial cristae Any of the inward folds of the mitochondrial inner membrane. Their number, extent, and shape differ in mitochondria from different tissues and organisms. They appear to be devices for increasing the surface area of the mitochondrial inner membrane, where the enzymes of electron transport and oxidative phosphorylation are found. Their shape can vary with the respiratory state of the mitochondria. UBERON:0004199 S-shaped body biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004199 stage II nephron|SSB The S-shaped body is the successor of the comma-shaped body that contributes to the morphogenesis of the nephron GO:0044616 modulation of relaxation of muscle in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044616 regulation of relaxation of muscle in other organism The process in which an organism effects a change in the relaxation of muscle in a second organism. UBERON:0004196 proximal convoluted tubule segment 1 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004196 segment 1 of proximal tubule|S1 portion of tubule|proximal tubule segment 1|S1 portion of renal tubule|S1 The S1 portion is the initial portion of the proximal convoluted tubule and is responsible for avid reabsorption of water and solutes[GO]. GO:0044617 modulation of relaxation of smooth muscle in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044617 regulation of relaxation of smooth muscle in other organism The process in which an organism effects a change in the relaxation of smooth muscle in a second organism. UBERON:0004197 proximal convoluted tubule segment 2 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004197 segment 2 of proximal tubule|S2 portion of tubule|proximal tubule segment 2|S2 portion of renal tubule|S2 The S2 portion of the tubule is involved in reabsorption of water and sodium chloride[GO]. GO:0044614 nuclear pore cytoplasmic filaments biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044614 cytoplasmic fibers of the nuclear pore complex|cytoplasmic fibers of the NPC Filamentous extensions on cytoplasmic face of the nuclear pore complex (NPC). In S. cerevisiae, Nup159p, Nup82p, and Nup42p contribute to the cytoplasmic filaments. In vertebrates, Nup358 is a major component. UBERON:0004194 long nephron biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004194 juxtamedullary nephron Long nephrons are associated with juxtamedullary glomeruli and extend to the inner medulla GO:0044615 nuclear pore nuclear basket biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044615 A filamentous, cage-like assembly on the nuclear face of the nuclear pore complex (NPC). In S. cerevisiae, Mlp1p and Mlp2p are two major components of the NPC nuclear basket. In vertebrates, Tpr is a major component. UBERON:0004195 short nephron biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004195 Short nephrons are associated with mid-cortical glomeruli, and have no short ascending limb, so the limb is situated in the outer medulla GO:0044612 nuclear pore linkers biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044612 Nup82 complex|Nic96 complex A substructure of the nuclear pore complex (NPC) that serves to connect members of the central transport channel (composed of FG-nucleoporins) to the core scaffold (composed of the inner and outer NPC rings). In S. cerevisiae, the linkers are Nic96p and Nup82p. In vertebrates, they are Nup93 and Nup88. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. Both linkers can be isolated in association with specific FG-nucleoporins, complexes that are sometimes referred to as the Nic96 complex (Nic96p-Nsp1p-Nup49p-Nup57p) and the Nup82 complex (Nup82p-Nup116p-Nup159p-Gle2p). UBERON:0004193 loop of Henle ascending limb thin segment biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004193 pars ascendens (tubulus attenuatus)|ascending limb thin segment of loop of Henle|thin ascending limb|thin ascending limb of loop of Henle|ascending thin limb A sub-portion of the loop of Henle in the nephron of the kidney that is permeable to ions but not to water GO:0044613 nuclear pore central transport channel biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044613 nuclear pore central plug|nuclear pore central channel|nuclear pore transport channel|karyopherin docking complex The central substructure of the nuclear pore complex (NPC), through which nucleocytoplasmic transport of RNAs, proteins and small molecules occurs. The central transport channel is filled with FG-nucleoporins, which form a selective barrier and provide a series of binding sites for transporter proteins. Characterized S. cerevisiae FG-nucleoporins include Nup159p, Nup145Np, Nup116p, Nup100p, Nsp1p, Nup57p, Nup49p, Nup42p, Nup53p, Nup59p/Asm4p, Nup60p and Nup1. Characterized vertebrate FG-nucleoporins include Nup214, Nup98, Nup62, Nup54, Nup58/45, NLP1, and Nup153. GO:0030068 obsolete lytic viral life cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030068 lytic viral life cycle OBSOLETE. (Was not defined before being made obsolete). GO:0030069 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030069 GO:0030066 obsolete cytochrome b6 biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030066 cytochrome b-563|cytochrome b6 OBSOLETE. (Was not defined before being made obsolete). GO:0030067 obsolete respiratory chain cytochrome b6 biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030067 respiratory chain cytochrome b6 OBSOLETE. (Was not defined before being made obsolete). GO:0030064 obsolete cell wall inner membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030064 cell wall inner membrane OBSOLETE. The peptidoglycan layer of the cell wall of Gram-negative bacteria. GO:0030065 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030065 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030062 TCA cycle enzyme complex Any of the heteromeric enzymes, located in the mitochondrion, that act in the tricarboxylic acid (TCA) cycle. GO:0030063 obsolete murein sacculus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030063 peptidoglycan layer|murein sacculus OBSOLETE. A structure formed of the cross-linked polymer peptidoglycan (also called murein) that forms a covalently closed net around a bacterial cell, and imparts structural stability to the bacterial cell wall. PR:000018345 interleukin-1 beta proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000018345 IL1B/ClvPrd An interleukin-1 beta that has been processed by proteolytic cleavage. GO:0030059 aralkylamine dehydrogenase (azurin) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030059 EC:1.4.9.2|RHEA:47796|MetaCyc:ARALKYLAMINE-DEHYDROGENASE-RXN tyramine dehydrogenase (azurin) activity|aromatic amine dehydrogenase (azurin) activity|arylamine dehydrogenase activity|aralkylamine:(azurin) oxidoreductase (deaminating) activity|dehydrogenase, arylamine (azurin) activity Catalysis of the reaction: H(2)O + arCH(2)NH(2) + 2 azurin = 2 reduced azurin + ArCHO + NH(3). The symbol arCH(2)NH(2) represents an aralkylamine and ArCHO is an aryl aldehyde. GO:0044621 modulation of cell migration in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044621 regulation of cell migration in other organism The process in which an organism effects a change in the process of cell migration in a second organism. CHEBI:140597 disubstituted aliphatic (S)-cyanohydrin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140597 GO:0044622 negative regulation of cell migration in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044622 Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration in a second organism. GO:0005099 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005099 CHEBI:140595 1-[(1Z)-octadecenyl]-2-oleoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_140595 GO:0044620 ACP phosphopantetheine attachment site binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044620 Interacting selectively and non-covalently with the attachment site of the phosphopantetheine prosthetic group of an acyl carrier protein (ACP). CHEBI:140596 monosubstituted aliphatic (S)-cyanohydrin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140596 GO:0005097 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005097 CHEBI:140593 N-acyl-1-[(1Z)-alkenyl]-2-acyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_140593 GO:0005098 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005098 CHEBI:140594 ethanediol derivative biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140594 GO:0005095 GTPase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005095 GIP Stops, prevents or reduces the activity of any enzyme that catalyzes the hydrolysis of GTP to GDP and orthophosphate. GO:0005096 GTPase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005096 Reactome:R-HSA-8985594|Reactome:R-HSA-416546|Reactome:R-HSA-5638007|Reactome:R-HSA-399935|Reactome:R-HSA-4093339|Reactome:R-HSA-194922|Reactome:R-HSA-428533|Reactome:R-HSA-9624893|Reactome:R-HSA-428522|Reactome:R-HSA-392513|Reactome:R-HSA-416559 Rac GAP activity|ARF GAP activity|ARF GTPase activator activity|Rac GTPase activator activity|Rab GTPase activator activity|Rho GAP activity|Ral GAP activity|RanGAP|Ran GAP activity|Rap GAP activity|GAP activity|Sar GAP activity|Ras GAP activity|Ras GTPase activator activity|Sar GTPase activator activity|Rap GTPase activator activity|Ran GTPase activator activity|Ral GTPase activator activity|Rho GTPase activator activity|Rab GAP activity Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP. GO:0044629 negative regulation of complement activation, classical pathway in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044629 Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the classical pathway, in a different organism. GO:0030050 vesicle transport along actin filament biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030050 Movement of a vesicle along an actin filament, mediated by motor proteins. GO:0044627 modulation of complement activation, classical pathway in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044627 regulation of complement activation, classical pathway in other organism A process that modulates the frequency, rate or extent of the classical pathway of complement activation, in a different organism. GO:0044628 positive regulation of complement activation, classical pathway in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044628 Any process that activates or increases the frequency, rate or extent of complement activation by the classical pathway, in a different organism. GO:0044625 envenomation resulting in negative regulation of cell migration in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044625 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the negative regulation of cell migration in the bitten organism. GO:0044626 envenomation resulting in positive regulation of cell migration in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044626 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the positive regulation of cell migration in the bitten organism. GO:0044623 positive regulation of cell migration in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044623 Any process that activates or increases the frequency, rate or extent of cell migration in a second organism. CHEBI:140599 alpha-D-xylose-(1->3)-alpha-D-xylose-(1->3)-beta-D-glucose-L-seryl residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140599 GO:0044624 envenomation resulting in modulation of cell migration in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044624 envenomation resulting in regulation of cell migration in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the modulation of cell migration in the bitten organism. CHEBI:139597 O(3)-[N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139597 GO:0030057 desmosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030057 Wikipedia:Desmosome spot desmosome|macula adherens A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism. GO:0030058 amine dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030058 EC:1.4.9.1|MetaCyc:AMINE-DEHYDROGENASE-RXN|UM-BBD_enzymeID:e0058|RHEA:30207 primary-amine dehydrogenase activity|primary-amine:acceptor oxidoreductase (deaminating)|methylamine dehydrogenase activity|primary-amine:(acceptor) oxidoreductase (deaminating)|MADH activity|amine: (acceptor) oxidoreductase (deaminating) Catalysis of the reaction: R-CH2-NH2 + H2O + acceptor = R-CHO + NH3 + reduced acceptor. CHEBI:139598 O(3)-[N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139598 GO:0030055 cell-substrate junction biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030055 cell-matrix junction A cell junction that forms a connection between a cell and the extracellular matrix. GO:0030056 hemidesmosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030056 Wikipedia:Hemidesmosome fibrous organelle|hemi-adherens junction|trans-epithelial attachment|epidermal attachment structure A cell-substrate junction (attachment structure) found in epithelial cells that links intermediate filaments to extracellular matrices via transmembrane complexes. In vertebrates, hemidesmosomes mediate contact between the basal side of epithelial cells and the basal lamina. In C. elegans, hemidesmosomes connect epithelial cells to distinct extracellular matrices on both the apical and basal cell surfaces. GO:0030053 obsolete immunophilin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030053 immunophilin OBSOLETE. Any member of a family of receptors that includes the major FK506 binding protein FKBP and cyclophilin. These two proteins are unrelated in amino-acid sequence, but both possess peptidyl-prolyl isomerase activity which is blocked by immunosuppressants that block signal-transduction pathways leading to T cell activation such as FK506 and rapamycin, which block FKBP, or cyclosporin A, which blocks cyclophilin. CHEBI:139593 4-O-methylxanthohumol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139593 GO:0030054 cell junction biolink:CellularComponent go-plus goslim_agr|goslim_drosophila|goslim_flybase_ribbon http://purl.obolibrary.org/obo/GO_0030054 Wikipedia:Cell_junction A cellular component that forms a specialized region of connection between two or more cells, or between a cell and the extracellular matrix, or between two membrane-bound components of a cell, such as flagella. GO:0030051 obsolete FK506-sensitive peptidyl-prolyl cis-trans isomerase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030051 FKBP|FK506-sensitive peptidyl-prolyl cis-trans isomerase|FK506 binding protein OBSOLETE. Interacts selectively with the immunosuppressant FK506, and possesses peptidyl-prolyl isomerase activity (catalysis of the reaction: peptidoproline (omega=180) = peptidylproline (omega=0)). GO:0030052 obsolete parvulin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030052 parvulin OBSOLETE. A peptidyl-prolyl isomerase isolated from Escherichia coli. It does not have any function as an immunophilin. CHEBI:139596 N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139596 GO:0030048 actin filament-based movement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030048 Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins. GO:0030049 muscle filament sliding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030049 The sliding of actin thin filaments and myosin thick filaments past each other in muscle contraction. This involves a process of interaction of myosin located on a thick filament with actin located on a thin filament. During this process ATP is split and forces are generated. GO:0044632 negative regulation of complement activation, lectin pathway in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044632 Any process that stops, prevents, or reduces the rate of complement activation by the lectin pathway, in a different organism. GO:0044633 modulation of complement activation, alternative pathway in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044633 regulation of complement activation, alternative pathway in other organism A process that modulates the frequency, rate or extent of complement activation, via the alternative pathway, in a different organism. GO:0044630 modulation of complement activation, lectin pathway in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044630 regulation of complement activation, lectin pathway in other organism A process that modulates the frequency, rate or extent of the lectin pathway of complement activation, in a different organism. GO:0044631 positive regulation of complement activation, lectin pathway in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044631 Any process that activates or increases the frequency, rate or extent of complement activation by the lectin pathway, in a different organism. GO:0044638 envenomation resulting in positive regulation of complement activation, classical pathway in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044638 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the positive regulation of complement activation via the classical pathway of the bitten/stung organism. GO:0044639 envenomation resulting in modulation of complement activation, lectin pathway in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044639 envenomation resulting in regulation of complement activation, lectin pathway in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of complement activation via the lectin pathway in the bitten/stung organism. GO:0044636 envenomation resulting in modulation of complement activation, classical pathway in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044636 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the regulation of complement activation via the classical pathway of the bitten/stung organism. GO:0044637 envenomation resulting in negative regulation of complement activation, classical pathway in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044637 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the negative regulation of complement activation via the classical pathway of the bitten/stung organism. GO:0044634 negative regulation of complement activation, alternative pathway in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044634 Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the alternative pathway, in a different organism. GO:0044635 positive regulation of complement activation, alternative pathway in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044635 Any process that activates or increases the frequency, rate or extent of complement activation by the alternative pathway, in a different organism. GO:0030046 parallel actin filament bundle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030046 Assembly of actin filament bundles in which the filaments are tightly packed (approximately 10-20 nm apart) and oriented with the same polarity. GO:0030047 actin modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030047 Covalent modification of an actin molecule. GO:0030044 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030044 GO:0030045 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030045 GO:0030042 actin filament depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030042 actin depolymerization|actin depolymerizing activity Disassembly of actin filaments by the removal of actin monomers from a filament. GO:0030043 actin filament fragmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030043 The severing of actin filaments into numerous short fragments, usually mediated by actin severing proteins. PR:000018344 interleukin-1 alpha proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000018344 IL1A/ClvPrd An interleukin-1 alpha that has been processed by proteolytic cleavage. GO:0030040 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030040 GO:0030041 actin filament polymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030041 actin polymerization|actin polymerizing activity Assembly of actin filaments by the addition of actin monomers to a filament. CHEBI:139580 O(3)-[N-acetyl-beta-D-glucosaminyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl]-L-threonine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139580 CHEBI:139581 O(3)-[N-acetyl-beta-D-glucosaminyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl]-L-serine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139581 GO:0030039 obsolete DNA unwinding factor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030039 DNA unwinding factor OBSOLETE. (Was not defined before being made obsolete). GO:0030037 actin filament reorganization involved in cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030037 actin filament reorganization during cell cycle|actin filament reorganisation involved in cell cycle The cell cycle process in which rearrangement of the spatial distribution of actin filaments and associated proteins occurs. GO:0030038 contractile actin filament bundle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030038 Assembly of actin filament bundles in which the filaments are loosely packed (approximately 30-60 nm apart) and arranged with opposing polarities; the loose packing allows myosin (usually myosin-II) to enter the bundle. GO:0005079 obsolete protein kinase A anchoring activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005079 A-kinase anchor protein activity|protein kinase A anchoring activity|AKAP activity OBSOLETE. Binds to protein kinase A and anchors it to a particular subcellular location. GO:0044643 envenomation resulting in positive regulation of complement activation, alternative pathway in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044643 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of complement activation via the alternative pathway in the bitten/stung organism. CHEBI:140575 alpha-D-xylose-(1->3)-beta-D-glucose-L-seryl residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140575 GO:0044644 envenomation resulting in negative regulation of complement activation, alternative pathway in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044644 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant negative regulation of complement activation via the alternative pathway in the bitten/stung organism. CHEBI:140576 beta-D-glucose-L-seryl residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140576 GO:0005077 obsolete MAP-kinase anchoring activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005077 MAP-kinase anchor protein activity|MAP-kinase anchoring activity OBSOLETE. Binds to MAP kinase and anchors it to a particular subcellular location. GO:0044641 envenomation resulting in positive regulation of complement activation, lectin pathway in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044641 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of complement activation via the lectin pathway in the bitten/stung organism. CHEBI:140573 alpha-D-glucosyl-L-tyrosyl residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140573 GO:0005078 MAP-kinase scaffold activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005078 MAP-kinase scaffold protein activity The binding activity of a molecule that functions as a physical support for the assembly of a multiprotein mitogen-activated protein kinase (MAPK) complex. Binds multiple kinases of the MAPKKK cascade, and also upstream signaling proteins, permitting those molecules to function in a coordinated way. Bringing together multiple enzymes and their substrates enables the signal to be transduced quickly and efficiently. GO:0044642 envenomation resulting in modulation of complement activation, alternative pathway in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044642 envenomation resulting in regulation of complement activation, alternative pathway in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of complement activation via the alternative pathway in the bitten/stung organism. CHEBI:140574 (1,4-alpha-D-glucosyl)(n)-L-tyrosyl residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140574 GO:0005075 obsolete pathway-specific SMAD protein biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005075 pathway-specific SMAD protein OBSOLETE. (Was not defined before being made obsolete). GO:0005076 obsolete receptor signaling protein serine/threonine kinase signaling protein activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005076 receptor signaling protein serine/threonine kinase signaling protein activity|receptor signalling protein serine/threonine kinase signalling protein activity OBSOLETE. (Was not defined before being made obsolete). GO:0044640 envenomation resulting in negative regulation of complement activation, lectin pathway in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044640 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant negative regulation of complement activation via the lectin pathway in the bitten/stung organism. CHEBI:140572 heparan sulfate alpha-D-N-sulfoglucosamine polyanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140572 CHEBI:82464 cis-9,10-epoxyoctadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82464 GO:0005073 obsolete common-partner SMAD protein biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005073 common-partner SMAD protein OBSOLETE. (Was not defined before being made obsolete). GO:0005074 obsolete inhibitory SMAD protein biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005074 inhibitory SMAD protein OBSOLETE. (Was not defined before being made obsolete). GO:0005082 obsolete receptor signaling protein tyrosine phosphatase signaling protein activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005082 receptor signaling protein tyrosine phosphatase signaling protein activity|receptor signalling protein tyrosine phosphatase signalling protein activity OBSOLETE. (Was not defined before being made obsolete). GO:0005083 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005083 GO:0005080 protein kinase C binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005080 PKC binding|protein kinase C alpha binding|PKC alpha binding|protein kinase C delta binding|protein kinase C eta binding|PKC delta binding|PKC eta binding Interacting selectively and non-covalently with protein kinase C. GO:0044649 envenomation resulting in cytolysis in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044649 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with cytolysis in the bitten organism. GO:0005081 obsolete receptor signaling protein serine/threonine phosphatase signaling protein activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005081 receptor signaling protein serine/threonine phosphatase signaling protein activity|receptor signalling protein serine/threonine phosphatase signalling protein activity OBSOLETE. (Was not defined before being made obsolete). GO:0044647 host-symbiont bicellular tight junction biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044647 host-pathogen tight junction|host-parasite tight junction An occluding cell-cell junction formed between the membranes of the apical end of an invading cell (e.g. a merozoite in Plasmodium) and a host target cell (e.g. erythrocyte for Plasmodium infection). The junction is a stable yet dynamic structure that moves around the symbiont cell during invasion, enclosing it in a vacuole surrounded by a membrane. GO:0044648 histone H3-K4 dimethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044648 The modification of histone H3 by addition of two methyl groups to lysine at position 4 of the histone. GO:0044645 modulation of complement activation in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044645 regulation of complement activation in other organism A process that modulates the frequency, rate or extent of complement activation in a different organism. CHEBI:140577 beta-D-glucosyl-L-threonyl residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140577 GO:0044646 envenomation resulting in modulation of complement activation in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044646 envenomation resulting in regulation of complement activation in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of complement activation in the bitten/stung organism. PR:000008998 interleukin-21 receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000008998 LR-beta|NR8|IL-21 receptor|lymphocyte receptor beta|novel interleukin receptor|IL21R|CD360|novel cytokine receptor 8|IL-21R|NILR A protein that is a translation product of the human IL21R gene or a 1:1 ortholog thereof. CHEBI:140578 alpha-D-xylose-(1->3)-beta-D-glucose-L-threonyl residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140578 GO:0030035 microspike assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030035 microspike biogenesis|microspike formation|microspike biosynthesis Formation of a microspike, a dynamic, actin-rich projection extending from the surface of a migrating animal cell. CHEBI:139575 monounsaturated fatty acyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139575 GO:0030036 actin cytoskeleton organization biolink:BiologicalProcess go-plus goslim_drosophila|goslim_pombe http://purl.obolibrary.org/obo/GO_0030036 actin cytoskeleton organization and biogenesis|actin cytoskeleton organisation|actin modulating activity A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. CHEBI:139576 octadecatrienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139576 GO:0030033 microvillus assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030033 microvillus biogenesis Formation of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell. GO:0030034 microvillar actin bundle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030034 Assembly of the parallel bundle of actin filaments at the core of a microvillus. CHEBI:139578 octadecadienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139578 GO:0030031 cell projection assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030031 cell projection biogenesis|formation of a cell surface projection Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon. PO:0028002 sporophyte development stage biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0028002 sporophytic phase (exact)|fase esporofítica (Spanish, exact)|sporophytic development stage (exact)|sporphyte phase (exact)|胞子体発生過程 (Japanese, exact) A whole plant development stage (PO:0007033) that has as primary participant a whole plant (PO:0000003) during the interval between fertilization (or apogamy) and death. CHEBI:139571 8-carboxy-8-demethylriboflavin 5'-phosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139571 GO:0030032 lamellipodium assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030032 lamellipodium biosynthesis|lamellipodium formation|lamellipodium biogenesis Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell. CHEBI:139572 hexadecenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139572 GO:0030030 cell projection organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030030 cell surface structure organization and biogenesis|cell projection organisation|cell projection organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon. CHEBI:139574 octadecenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139574 CHEBI:139590 primary alpha-hydroxy ketone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139590 CHEBI:139592 tertiary alpha-hydroxy ketone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139592 GO:0030028 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030028 GO:0030029 actin filament-based process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030029 microfilament-based process Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins. GO:0030026 cellular manganese ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030026 manganese homeostasis Any process involved in the maintenance of an internal steady state of manganese ions at the level of a cell. UBERON_CORE:transitively_distally_connected_to transitively distally connected to biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/uberon/core#transitively_distally_connected_to transitively_distally_connected_to . GO:0030027 lamellipodium biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030027 Wikipedia:Lamellipodia A thin sheetlike process extended by the leading edge of a migrating cell or extending cell process; contains a dense meshwork of actin filaments. CHEBI:140564 delta-cadinene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140564 GO:0044654 starch alpha-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044654 EC:3.2.1.- Catalysis of the reaction: starch + H2O = alpha-D-glucose. GO:0044655 phagosome reneutralization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044655 phagosomal reneutralization|phagosome pH elevation Any process that increases the pH of the phagosome, measured by the concentration of the hydrogen ion, as part of the process of phagosome maturation. GO:0044652 adhesion of symbiont to host endothelial cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044652 The attachment of a symbiont to a host endothelial cell via adhesion molecules, general stickiness etc., either directly or indirectly. GO:0005088 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005088 GO:0044653 dextrin alpha-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044653 EC:3.2.1.- Catalysis of the reaction: dextrin + H2O = alpha-D-glucose. GO:0005089 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005089 GO:0044650 adhesion of symbiont to host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044650 The attachment of a symbiont to a host cell via adhesion molecules, general stickiness etc., either directly or indirectly. GO:0005086 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005086 CHEBI:140561 (1->4)-3,6-bis(phospho)-alpha-D-glucan polyanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140561 GO:0044651 adhesion of symbiont to host epithelial cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044651 The attachment of a symbiont to a host epithelial cell via adhesion molecules, general stickiness etc., either directly or indirectly. GO:0005087 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005087 GO:0005084 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005084 GO:0005085 guanyl-nucleotide exchange factor activity biolink:MolecularActivity go-plus goslim_chembl|goslim_yeast|goslim_drosophila http://purl.obolibrary.org/obo/GO_0005085 Reactome:R-HSA-5218829|Reactome:R-HSA-442732|Reactome:R-HSA-350769|Reactome:R-HSA-9695853|Reactome:R-HSA-5655347|Reactome:R-HSA-171026|Reactome:R-HSA-1306972|Reactome:R-HSA-420883|Reactome:R-HSA-9664991|Reactome:R-HSA-2730840|Reactome:R-HSA-399995|Reactome:R-HSA-5637808|Reactome:R-HSA-5655326|Reactome:R-HSA-416530|Reactome:R-HSA-6811414|Reactome:R-HSA-8877311|Reactome:R-HSA-3928633|Reactome:R-HSA-210977|Reactome:R-HSA-442314|Reactome:R-HSA-418856|Reactome:R-HSA-180687|Reactome:R-HSA-9607304|Reactome:R-HSA-9639286|Reactome:R-HSA-8877998|Reactome:R-HSA-9660824|Reactome:R-HSA-9026891|Reactome:R-HSA-5655277|Reactome:R-HSA-9033292|Reactome:R-HSA-9665707|Reactome:R-HSA-3928632|Reactome:R-HSA-379048|Reactome:R-HSA-169904|Reactome:R-HSA-8877308|Reactome:R-HSA-109817|Reactome:R-HSA-8876190|Reactome:R-HSA-5637806|Reactome:R-HSA-187746|Reactome:R-HSA-8876191|Reactome:R-HSA-9032067|Reactome:R-HSA-1250463|Reactome:R-HSA-2029445|Reactome:R-HSA-8876616|Reactome:R-HSA-156913|Reactome:R-HSA-2029451|Reactome:R-HSA-186834|Reactome:R-HSA-5655241|Reactome:R-HSA-5617816|Reactome:R-HSA-8850041|Reactome:R-HSA-428917|Reactome:R-HSA-9032798|Reactome:R-HSA-3928612|Reactome:R-HSA-109807|Reactome:R-HSA-9670436|Reactome:R-HSA-9029158|Reactome:R-HSA-8876188|Reactome:R-HSA-3928628|Reactome:R-HSA-6811429|Reactome:R-HSA-8982637|Reactome:R-HSA-9666428|Reactome:R-HSA-8851827|Reactome:R-HSA-5654426|Reactome:R-HSA-8876454|Reactome:R-HSA-5623521|Reactome:R-HSA-9672163|Reactome:R-HSA-5218850|Reactome:R-HSA-8877612|Reactome:R-HSA-2029467|Reactome:R-HSA-5654647|Reactome:R-HSA-399938|Reactome:R-HSA-8877813|Reactome:R-HSA-9665700|Reactome:R-HSA-418850|Reactome:R-HSA-2424476|Reactome:R-HSA-442291|Reactome:R-HSA-9666430|Reactome:R-HSA-751029|Reactome:R-HSA-3928642|Reactome:R-HSA-5672965|Reactome:R-HSA-9703441|Reactome:R-HSA-2424477|Reactome:R-HSA-8851877|Reactome:R-HSA-5218839|Reactome:R-HSA-177938|Reactome:R-HSA-9665408|Reactome:R-HSA-825631|Reactome:R-HSA-5654402|Reactome:R-HSA-5654600|Reactome:R-HSA-392870|Reactome:R-HSA-8876193|Reactome:R-HSA-5654618|Reactome:R-HSA-380073|Reactome:R-HSA-389348|Reactome:R-HSA-5686071|Reactome:R-HSA-3928592|Reactome:R-HSA-5686318|Reactome:R-HSA-1433471|Reactome:R-HSA-1225957|Reactome:R-HSA-4093336|Reactome:R-HSA-8851899|Reactome:R-HSA-1433415|Reactome:R-HSA-8853307|Reactome:R-HSA-114544|Reactome:R-HSA-9672170|Reactome:R-HSA-1168636|Reactome:R-HSA-9640167|Reactome:R-HSA-170979|Reactome:R-HSA-354173|Reactome:R-HSA-8875320|Reactome:R-HSA-939265|Reactome:R-HSA-392054|Reactome:R-HSA-2485180|Reactome:R-HSA-1250498|Reactome:R-HSA-389350|Reactome:R-HSA-8875591|Reactome:R-HSA-1225951|Reactome:R-HSA-9619803|Reactome:R-HSA-8877760|Reactome:R-HSA-445064|Reactome:R-HSA-8876837|Reactome:R-HSA-205039|Reactome:R-HSA-379044|Reactome:R-HSA-428750|Reactome:R-HSA-8848618|Reactome:R-HSA-5654413|Reactome:R-HSA-203977|Reactome:R-HSA-9665404|Reactome:R-HSA-194518|Reactome:R-HSA-392195|Reactome:R-HSA-3928651|Reactome:R-HSA-6811418|Reactome:R-HSA-8875568|Reactome:R-HSA-5654663|Reactome:R-HSA-9634418|Reactome:R-HSA-428535|Reactome:R-HSA-8875318|Reactome:R-HSA-8876615|Reactome:R-HSA-9624845|Reactome:R-HSA-177945|Reactome:R-HSA-416588|Reactome:R-HSA-6807868|Reactome:R-HSA-5654392|Reactome:R-HSA-442273|Reactome:R-HSA-8964604|Reactome:R-HSA-1250383|Reactome:R-HSA-5623508|Reactome:R-HSA-8877451|Reactome:R-HSA-749453|Reactome:R-HSA-2179407|Reactome:R-HSA-419166|Reactome:R-HSA-9665009|Reactome:R-HSA-3965444|Reactome:R-HSA-418579|Reactome:R-HSA-5694409|Reactome:R-HSA-8982640|Reactome:R-HSA-194913|Reactome:R-HSA-8877475 Rap guanyl-nucleotide exchange factor activity|GDS|guanyl-nucleotide release factor activity|Sar guanyl-nucleotide exchange factor activity|Ras guanyl-nucleotide exchange factor activity|RhoGEF|GNRP|GEF|cAMP-dependent guanyl-nucleotide exchange factor activity|Rab guanyl-nucleotide exchange factor activity|Rac guanyl-nucleotide exchange factor activity|ARF guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|Rho guanine nucleotide exchange factor|GDP-dissociation stimulator activity|Ral guanyl-nucleotide exchange factor activity|guanyl-nucleotide releasing factor|Ran guanyl-nucleotide exchange factor activity Stimulates the exchange of guanyl nucleotides associated with a GTPase. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase. GO:0005093 Rab GDP-dissociation inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005093 Prevents the dissociation of GDP from the small GTPase Rab, thereby preventing GTP from binding. GO:0005094 Rho GDP-dissociation inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005094 Prevents the dissociation of GDP from the small GTPase Rho, thereby preventing GTP from binding. GO:0005091 guanyl-nucleotide exchange factor adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005091 The binding activity of a molecule that brings together a guanyl-nucleotide exchange factor and one or more other proteins, permitting them to function in a coordinated way. GO:0005092 GDP-dissociation inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005092 GDI Prevents the dissociation of GDP from a GTPase, thereby preventing GTP from binding. GO:0044658 pore formation in membrane of host by symbiont biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044658 The aggregation, arrangement and bonding together of a set of components by an organism to form a pore complex in a membrane of a host organism. GO:0044659 viral release from host cell by cytolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044659 VZ:1077 viral exit from host cell by cytolysis|cytolysis by virus of host cell|lytic viral release|lytic viral life cycle|viral release by host cell lysis|viral release by cell lysis The killing by a virus of a cell by means of the rupture of cell membranes and the loss of cytoplasm. GO:0005090 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005090 GO:0044656 regulation of post-lysosomal vacuole size biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044656 regulation of post-lysosome size Any process that modulates the volume of a post-lysosomal vacuole, a membrane-bounded intracellular vesicle formed late in the endocytic pathway when the pH in the vacuole becomes neutral prior to exocytosis. GO:0044657 pore formation in membrane of other organism during symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044657 The aggregation, arrangement and bonding together of a set of components by an organism to form a pore complex in a membrane of another organism, occurring as part of a symbiotic interaction. GO:0030024 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030024 GO:0030025 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030025 GO:0030022 obsolete adhesive extracellular matrix constituent biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030022 adhesive extracellular matrix constituent OBSOLETE. A constituent of the extracellular matrix that facilitates attachment of cells to the matrix. CHEBI:139588 alpha-hydroxy ketone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139588 GO:0030023 extracellular matrix constituent conferring elasticity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030023 core matrisome|core extracellular matrix|elastin A component of the extracellular matrix that enables the matrix to recoil after transient stretching. CHEBI:139589 retinoid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139589 GO:0030020 extracellular matrix structural constituent conferring tensile strength biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030020 core matrisome|core extracellular matrix A constituent of the extracellular matrix that enables the matrix to resist longitudinal stress. GO:0030021 extracellular matrix structural constituent conferring compression resistance biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030021 core matrisome|core extracellular matrix A constituent of the extracellular matrix that enables the matrix to resist compressive forces; often a proteoglycan. CHEBI:139583 (R,R)-bis(2-oleoylglycero)-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139583 CHEBI:139585 (R,R)-2-oleoylglycero-1-phospho-1'-glycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139585 UBERON:0004264 lower leg skin biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004264 hind limb middle limb segment skin|hind limb zeugopod skin A zone of skin that is part of a lower leg [Automatically generated definition]. UBERON:0004265 outflow tract myocardium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004265 cardiac muscle of outflow tract|outflow tract cardiac muscle|heart myocardium of outflow tract|outflow tract muscle of heart|heart muscle of outflow tract|muscle of heart of outflow tract|outflow tract heart muscle|myocardium of outflow tract|outflow tract heart myocardium A myocardium that is part of a outflow tract [Automatically generated definition]. UBERON:0004262 upper leg skin biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004262 hind limb stylopod skin|skin of thigh|skin of upper leg|thigh skin|hindlimb stylopod skin A zone of skin that is part of a hindlimb stylopod [Automatically generated definition]. UBERON:0004263 upper arm skin biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004263 skin of arm stylopod|arm stylopod skin|skin of upper arm A zone of skin that is part of a forelimb stylopod [Automatically generated definition]. UBERON:0004260 upper arm blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004260 forelimb stylopod blood vessel A blood vessel that is part of a forelimb stylopod [Automatically generated definition]. UBERON:0004261 lower leg blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004261 hindlimb zeugopod blood vessel A blood vessel that is part of a lower leg [Automatically generated definition]. UBERON:0004268 lower arm connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004268 A portion of connective tissue that is part of a lower arm [Automatically generated definition]. UBERON:0004269 upper arm connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004269 A portion of connective tissue that is part of a forelimb stylopod [Automatically generated definition]. UBERON:0004266 upper leg connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004266 A portion of connective tissue that is part of a hindlimb stylopod [Automatically generated definition]. UBERON:0004267 back connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004267 mesenchyne of back A portion of connective tissue that is part of a back [Automatically generated definition]. CHEBI:33404 3-hydroxypropionic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33404 CHEBI:33405 hydracid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33405 CHEBI:33406 organoarsenic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33406 CHEBI:33407 arsenic oxoacid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33407 CHEBI:33408 pnictogen oxoacid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33408 CHEBI:33409 methylarsonate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33409 UBERON:0004253 skin muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004253 skin muscle organ|integumental system muscle|muscle of integumental system|muscle organ of skin Any muscle organ that is part of a skin of body [Automatically generated definition]. UBERON:0004254 forelimb zeugopod muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004254 muscle of forearm|lower arm muscle|forearm muscle|wing zeugopod muscle Any muscle organ that is part of a forelimb zeugopod (lower arm)[Automatically generated definition]. UBERON:0004251 hindlimb zeugopod bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004251 bone of hindlimb middle limb segment|intermediate segment of free lower limb bone organ|bone of zeugopod of leg|zeugopod of hind limb bone|bone of hind limb zeugopod|bone organ of middle limb segment of hindlimb|bone of inferior member zeugopod|zeugopod of inferior member bone|bone of intermediate segment of free lower limb|zeugopod of leg bone organ|bone organ of zeugopod of hindlimb|middle limb segment of hindlimb bone|bone of lower leg|middle limb segment of hind limb bone|bone organ of zeugopod of inferior member|bone organ of middle limb segment of inferior member|middle limb segment of inferior member bone|bone organ of zeugopod of hind limb|bone organ of middle limb segment of hind limb|zeugopod of hindlimb bone|bone of inferior member middle limb segment|bone of hind limb middle limb segment|inferior member zeugopod bone organ|lower extremity middle limb segment bone|hind limb zeugopod bone organ|bone of hindlimb zeugopod|bone organ of zeugopod of lower extremity|hindlimb middle limb segment bone organ|zeugopod of lower extremity bone organ|bone organ of lower extremity zeugopod|bone organ of middle limb segment of lower extremity|hindlimb zeugopod bone|bone of lower extremity middle limb segment|hind limb middle limb segment bone|lower extremity zeugopod bone organ|middle limb segment of lower extremity bone organ|inferior member middle limb segment bone|bone organ of hindlimb middle limb segment|bone organ of hind limb zeugopod|zeugopod of hind limb bone organ|bone organ of inferior member zeugopod|zeugopod of inferior member bone organ|bone of middle limb segment of hindlimb|lower leg bone|intermediate segment of free lower limb bone|bone organ of zeugopod of leg|bone of zeugopod of inferior member|middle limb segment of hind limb bone organ|middle limb segment of hindlimb bone organ|bone organ of intermediate segment of free lower limb|bone of zeugopod of hind limb|middle limb segment of inferior member bone organ|zeugopod of leg bone|bone of zeugopod of hindlimb|bone organ of lower leg|bone of middle limb segment of inferior member|zeugopod of hindlimb bone organ|lower extremity middle limb segment bone organ|bone of middle limb segment of hind limb|bone organ of inferior member middle limb segment|bone of zeugopod of lower extremity|bone organ of hind limb middle limb segment|inferior member zeugopod bone|hind limb zeugopod bone|bone organ of hindlimb zeugopod|hindlimb zeugopod bone organ|hindlimb middle limb segment bone|bone of lower extremity zeugopod|bone of middle limb segment of lower extremity|zeugopod of lower extremity bone|hind limb middle limb segment bone organ|inferior member middle limb segment bone organ|bone organ of lower extremity middle limb segment|middle limb segment of lower extremity bone|lower extremity zeugopod bone A bone that is part of a lower leg [Automatically generated definition]. UBERON:0004252 hindlimb stylopod muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004252 upper leg muscle|muscle of thigh|thigh muscle Any muscle organ that is part of a hindlimb stylopod (upper leg)[Automatically generated definition]. UBERON:0004250 upper arm bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004250 humerus A bone that is part of a forelimb stylopod [Automatically generated definition]. CHEBI:33402 sulfur oxoacid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33402 CHEBI:33403 elemental sulfur biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33403 UBERON:0004259 lower arm blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004259 forelimb zeugopod blood vessel A blood vessel that is part of a lower arm [Automatically generated definition]. UBERON:0004257 upper leg blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004257 thigh blood vessel|blood vessel of stylopod of hind limb|blood vessel of stylopod of hindlimb|hindlimb stylopod blood vessel|blood vessel of thigh|hind limb stylopod blood vessel|blood vessel of upper leg A blood vessel that is part of a hindlimb stylopod [Automatically generated definition]. UBERON:0004258 back blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004258 blood vessel of back A blood vessel that is part of a back [Automatically generated definition]. UBERON:0004255 forelimb stylopod muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004255 muscle of upper arm|muscle of arm|wing stylopod muscle|skeletal muscle of upper arm|upper arm muscle Any muscle organ that is part of a forelimb stylopod (upper arm)[Automatically generated definition]. UBERON:0004256 hindlimb zeugopod muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004256 lower leg muscle|calf muscle|muscle of leg Any muscle organ that is part of a hindlimb zeugopod (lower leg) [Automatically generated definition]. UBERON:0004242 bronchus smooth muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004242 bronchi smooth muscle|bronchial trunk smooth muscle|involuntary muscle of bronchi|involuntary muscle of bronchial trunk|involuntary muscle of bronchus|bronchus smooth muscle tissue|bronchial trunk smooth muscle tissue|bronchi smooth muscle tissue|smooth muscle tissue of bronchi|smooth muscle of bronchi|smooth muscle tissue of bronchial trunk|smooth muscle of bronchial trunk|non-striated muscle of bronchi|non-striated muscle of bronchial trunk|bronchus involuntary muscle|bronchial trunk involuntary muscle|non-striated muscle of bronchus|bronchi involuntary muscle|smooth muscle of bronchus|bronchial smooth muscle|smooth muscle tissue of bronchus|bronchi non-striated muscle|bronchial trunk non-striated muscle|bronchus non-striated muscle A portion of smooth muscle tissue that is part of a bronchus [Automatically generated definition]. UBERON:0004243 prostate gland smooth muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004243 involuntary muscle of prostate gland|non-striated muscle of prostate|prostate involuntary muscle|muscular tissue of prostate|substantia muscularis prostatae|smooth muscle of prostate|smooth muscle tissue of prostate|prostate gland smooth muscle tissue|prostate non-striated muscle|prostate smooth muscle|non-striated muscle of prostate gland|involuntary muscle of prostate|smooth muscle of prostate gland|smooth muscle tissue of prostate gland|prostate gland involuntary muscle|prostate smooth muscle tissue|prostate gland non-striated muscle A portion of smooth muscle tissue that is part of a prostate gland [Automatically generated definition]. UBERON:0004240 gall bladder smooth muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004240 gallbladder non-striated muscle|non-striated muscle of gall bladder|gallbladder smooth muscle|gallbladder involuntary muscle|involuntary muscle of gallbladder|smooth muscle of gall bladder|smooth muscle tissue of gall bladder|gall bladder non-striated muscle|gall bladder smooth muscle tissue|biliary smooth muscle|smooth muscle tissue of gallbladder|smooth muscle of gallbladder|involuntary muscle of gall bladder|non-striated muscle of gallbladder|gallbladder smooth muscle tissue|gall bladder involuntary muscle A portion of smooth muscle tissue that is part of a gallbladder [Automatically generated definition]. UBERON:0004248 pedal digit bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004248 foot digit bone organ|toe bone|bone of digit of foot|digitus pedis bone organ|foot digit bone|toe bone organ|digital bone of pes|foot digit bone|digital bone of foot|digit of foot bone|digitus pedis bone|hind limb digit bone A bone that is part of a hindlimb digit. Typically phalanges but may include sesamoids. UBERON:0004249 manual digit bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004249 finger bone|hand digit bone|hand digit bone|digital bone of hand|digital bone of manus|fore limb digit bone A bone that is part of a forelimb digit. Typically phalanges but may include sesamoids. UBERON:0004246 outflow tract smooth muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004246 outflow tract non-striated muscle|outflow tract smooth muscle tissue|involuntary muscle of outflow tract|outflow tract involuntary muscle|smooth muscle tissue of outflow tract|smooth muscle of outflow tract|non-striated muscle of outflow tract A portion of smooth muscle tissue that is part of a outflow tract [Automatically generated definition]. UBERON:0004247 bone of dorsum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004247 back bone|bone of back|dorsal region bone A bone that is part of the dorsal region of an animal. UBERON:0004245 oviduct smooth muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004245 non-striated muscle of fallopian tube|fallopian tube smooth muscle tissue|smooth muscle of fallopian tube|smooth muscle tissue of fallopian tube|fallopian tube non-striated muscle|fallopian tube smooth muscle|fallopian tube involuntary muscle|involuntary muscle of fallopian tube A portion of smooth muscle tissue that is part of a fallopian tube [Automatically generated definition]. UBERON:0004231 anal region smooth muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004231 anal region smooth muscle tissue|anal part of perineum non-striated muscle|anal triangle involuntary muscle|smooth muscle tissue of anal triangle|smooth muscle of anal triangle|anal region non-striated muscle|anal part of perineum smooth muscle tissue|anal part of perineum smooth muscle|non-striated muscle of anal triangle|involuntary muscle of anal part of perineum|involuntary muscle of anal region|anal region involuntary muscle|anal triangle non-striated muscle|anal part of perineum involuntary muscle|smooth muscle tissue of anal part of perineum|smooth muscle of anal part of perineum|anal triangle smooth muscle|anal triangle smooth muscle tissue|smooth muscle tissue of anal region|involuntary muscle of anal triangle|smooth muscle of anal region|non-striated muscle of anal part of perineum|non-striated muscle of anal region A portion of smooth muscle tissue that is part of an anal region [Automatically generated definition]. UBERON:0004232 lymphatic vessel smooth muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004232 smooth muscle of lymph vessel|smooth muscle tissue of lymph vessel|lymph vessel non-striated muscle|lymphatic vessel involuntary muscle|lymph vessel smooth muscle tissue|lymph vessel smooth muscle|non-striated muscle of lymphatic vessel|involuntary muscle of lymph vessel|smooth muscle of lymphatic vessel|smooth muscle tissue of lymphatic vessel|lymphatic vessel non-striated muscle|lymph vessel involuntary muscle|lymphatic vessel smooth muscle tissue|involuntary muscle of lymphatic vessel|non-striated muscle of lymph vessel A portion of smooth muscle tissue that is part of a lymphatic vessel [Automatically generated definition]. UBERON:0004230 urinary bladder neck smooth muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004230 neck of urinary bladder non-striated muscle|bladder neck smooth muscle tissue|smooth muscle of bladder neck|smooth muscle tissue of bladder neck|neck of bladder smooth muscle tissue|non-striated muscle of vesical neck|non-striated muscle of urinary bladder neck|neck of urinary bladder smooth muscle|involuntary muscle of neck of urinary bladder|neck of bladder non-striated muscle|smooth muscle of vesical neck|bladder neck non-striated muscle|urinary bladder neck involuntary muscle|smooth muscle of urinary bladder neck|smooth muscle tissue of vesical neck|neck of urinary bladder smooth muscle tissue|vesical neck involuntary muscle|smooth muscle tissue of urinary bladder neck|neck of bladder smooth muscle|bladder neck smooth muscle|vesical neck non-striated muscle|involuntary muscle of neck of bladder|urinary bladder neck muscle|urinary bladder neck non-striated muscle|bladder neck involuntary muscle|neck of bladder involuntary muscle|involuntary muscle of bladder neck|vesical neck smooth muscle|smooth muscle tissue of neck of urinary bladder|smooth muscle of neck of urinary bladder|trigonal muscle of urinary bladder|involuntary muscle of vesical neck|involuntary muscle of urinary bladder neck|neck of urinary bladder involuntary muscle|non-striated muscle of neck of urinary bladder|smooth muscle tissue of neck of bladder|smooth muscle of neck of bladder|urinary bladder neck smooth muscle tissue|non-striated muscle of neck of bladder|vesical neck smooth muscle tissue|non-striated muscle of bladder neck|trigonal muscle A portion of smooth muscle tissue that is part of a neck of urinary bladder [Automatically generated definition]. UBERON:0004239 small intestine smooth muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004239 smooth muscle tissue of small bowel|smooth muscle of small bowel|small bowel smooth muscle tissue|non-striated muscle of small bowel|small intestine involuntary muscle|smooth muscle tissue of small intestine|smooth muscle of small intestine|non-striated muscle of small intestine|small bowel non-striated muscle|small bowel involuntary muscle|small bowel smooth muscle|involuntary muscle of small bowel|small intestine non-striated muscle|small intestine smooth muscle tissue|involuntary muscle of small intestine A portion of smooth muscle tissue that is part of a small intestine [Automatically generated definition]. UBERON:0004237 blood vessel smooth muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004237 non-striated muscle of blood vessel|smooth muscle of blood vessel|smooth muscle tissue of blood vessel|vascular smooth muscle|blood vessel smooth muscle tissue|blood vessel non-striated muscle|vascular smooth muscle tissue|involuntary muscle of blood vessel|blood vessel involuntary muscle smooth muscle found within, and composing the majority of the wall of blood vessels. UBERON:0004238 spleen smooth muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004238 smooth muscle of spleen|smooth muscle tissue of spleen|spleen non-striated muscle|spleen smooth muscle tissue|involuntary muscle of spleen|spleen involuntary muscle|non-striated muscle of spleen A portion of smooth muscle tissue that is part of a spleen [Automatically generated definition]. UBERON:0004235 mammary gland smooth muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004235 smooth muscle tissue of mammary gland A portion of smooth muscle tissue that is part of a mammary gland [Automatically generated definition]. UBERON:0004236 arteriole smooth muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004236 A portion of smooth muscle tissue that is part of an arteriole [Automatically generated definition]. UBERON:0004233 lower respiratory tract smooth muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004233 lower respiratory tract non-striated muscle|lower respiratory tract smooth muscle tissue|involuntary muscle of lower respiratory tract|lower respiratory tract involuntary muscle|smooth muscle tissue of lower respiratory tract|smooth muscle of lower respiratory tract|non-striated muscle of lower respiratory tract A portion of smooth muscle tissue that is part of a lower respiratory tract [Automatically generated definition]. UBERON:0004234 iris smooth muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004234 non-striated muscle of iris|iris involuntary muscle|smooth muscle of iris|smooth muscle tissue of iris|iris non-striated muscle|iridial smooth muscle|involuntary muscle of iris|iris smooth muscle tissue A portion of smooth muscle tissue that is part of a iris [Automatically generated definition]. UBERON:0004290 dermomyotome biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004290 dermamyotome|dermomyotomes The bilaminar epithelium formed from the myotome and dermatome. UBERON:0004297 respiratory system blood vessel smooth muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004297 smooth muscle tissue of blood vessel of respiratory system A blood vessel smooth muscle that is part of a respiratory system [Automatically generated definition]. UBERON:0004295 sympathetic nerve trunk biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004295 nerve trunk of sympathetic nervous system|nerve trunk of sympathetic part of autonomic division of nervous system|sympathetic nervous system nerve trunk A nerve trunk that is part of a sympathetic nervous system [Automatically generated definition]. UBERON:0004296 respiratory system lymphatic vessel smooth muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004296 smooth muscle of lymph vessel of respiratory system A lymphatic vessel smooth muscle that is part of a respiratory system [Automatically generated definition]. UBERON:0004293 parasympathetic nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004293 nerve of parasympathetic nervous system A nerve that is part of a parasympathetic nervous system [Automatically generated definition]. UBERON:0004294 glomerular capillary endothelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004294 renal glomerulus capillary endothelium An endothelium that is part of a glomerular capillary. PR:000008942 insulin-like growth factor II biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000008942 multiplication-stimulating polypeptide|IGF2|Igf-2|IGF-II|somatomedin-A A protein that is a translation product of the human IGF2 gene or a 1:1 ortholog thereof. UBERON:0004291 heart rudiment biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004291 heart cone|rudimentary heart A cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube. UBERON:0004292 cardiac skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004292 trigonum fibrosum dextrum cordis|cardiac fibrous skeleton|anulus fibrosus sinister cordis|skeleton of heart|trigonum fibrosum sinistrum cordis|heart fibrous skeleton|anulus fibrosus dexter cordis|trigona fibrosa|fibrous skeleton of heart Dense connective tissue that separates the atria from the ventricles and provides physical support for the heart. PR:000008910 interferon-induced helicase C domain-containing protein 1 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000008910 MDA5|melanoma differentiation-associated protein 5|interferon-induced with helicase C domain protein 1|RH116|murabutide down-regulated protein|IFIH1|MDA-5|helicase with 2 CARD domains|RNA helicase-DEAD box protein 116|interferon induced with helicase C domain protein 1|helicard A protein that is a translation product of the human IFIH1 gene or a 1:1 ortholog thereof. UBERON:0004288 skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004288 set of bones of body|set of all bones Anatomical cluster that consists of all the skeletal elements (eg., bone, cartilage, and teeth) of the body. UBERON:0004275 third ventricle choroid plexus epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004275 third ventricle epithelium of chorioid plexus of cerebral hemisphere|third ventricle choroid plexus epithelial tissue|third ventricle chorioid plexus of cerebral hemisphere epithelial tissue|chorioid plexus of cerebral hemisphere epithelial tissue of third ventricle|choroid plexus epithelial tissue of third ventricle|third ventricle chorioid plexus of cerebral hemisphere epithelium|third ventricle epithelial tissue of choroid plexus|epithelium of chorioid plexus of cerebral hemisphere of third ventricle|third ventricle epithelial tissue of chorioid plexus of cerebral hemisphere|epithelial tissue of chorioid plexus of cerebral hemisphere of third ventricle|epithelium of choroid plexus of third ventricle|choroid plexus epithelium of third ventricle|epithelial tissue of choroid plexus of third ventricle|chorioid plexus of cerebral hemisphere epithelium of third ventricle|third ventricle epithelium of choroid plexus A choroid plexus epithelium that is part of a third ventricle [Automatically generated definition]. UBERON:0004276 fourth ventricle choroid plexus epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004276 chorioid plexus of cerebral hemisphere epithelium of fourth ventricle|fourth ventricle epithelium of choroid plexus|epithelial tissue of choroid plexus of fourth ventricle|choroid plexus epithelium of fourth ventricle|fourth ventricle epithelium of chorioid plexus of cerebral hemisphere|epithelial tissue of chorioid plexus of cerebral hemisphere of fourth ventricle|epithelium of choroid plexus of fourth ventricle|epithelium of chorioid plexus of cerebral hemisphere of fourth ventricle|fourth ventricle choroid plexus epithelial tissue|fourth ventricle chorioid plexus of cerebral hemisphere epithelial tissue|fourth ventricle chorioid plexus of cerebral hemisphere epithelium|fourth ventricle epithelial tissue of choroid plexus|choroid plexus epithelial tissue of fourth ventricle|fourth ventricle epithelial tissue of chorioid plexus of cerebral hemisphere|chorioid plexus of cerebral hemisphere epithelial tissue of fourth ventricle A choroid plexus epithelium that is part of a fourth ventricle [Automatically generated definition]. UBERON:0004273 cartilaginous joint suture biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004273 articulatio cartilaginea suture of cranium|cranial suture of cartilaginous joint|articulatio cartilaginea cranial suture|cartilaginous joint cranial sutures set|cartilaginous joint cranial sutures|cranial sutures set of articulatio cartilaginea|cranial sutures of articulatio cartilaginea|suture of cranium of cartilaginous joint|cranium suture of articulatio cartilaginea|cartilaginous joint cranial suture|articulatio cartilaginea cranium suture|articulatio cartilaginea cranial sutures set|articulatio cartilaginea cranial sutures|cartilaginous joint suture of cranium|cranium suture of cartilaginous joint|suture of cranium of articulatio cartilaginea|cranial sutures of cartilaginous joint|cranial sutures set of cartilaginous joint|cartilaginous joint cranium suture|cranial suture of articulatio cartilaginea A cranial suture that is part of a cartilaginous joint [Automatically generated definition]. UBERON:0004274 lateral ventricle choroid plexus epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004274 lateral ventricle epithelial tissue of chorioid plexus of cerebral hemisphere|epithelium of choroid plexus of lateral ventricle|epithelial tissue of chorioid plexus of cerebral hemisphere of lateral ventricle|choroid plexus epithelium of lateral ventricle|epithelial tissue of choroid plexus of lateral ventricle|chorioid plexus of cerebral hemisphere epithelium of lateral ventricle|lateral ventricle epithelium of choroid plexus|lateral ventricle epithelium of chorioid plexus of cerebral hemisphere|lateral ventricle choroid plexus epithelial tissue|lateral ventricle chorioid plexus of cerebral hemisphere epithelial tissue|chorioid plexus of cerebral hemisphere epithelial tissue of lateral ventricle|choroid plexus epithelial tissue of lateral ventricle|lateral ventricle chorioid plexus of cerebral hemisphere epithelium|lateral ventricle epithelial tissue of choroid plexus|epithelium of chorioid plexus of cerebral hemisphere of lateral ventricle A choroid plexus epithelium that is part of a lateral ventricle [Automatically generated definition]. UBERON:0004271 outflow tract pericardium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004271 pericardium of outflow tract A pericardium that is part of a outflow tract [Automatically generated definition]. UBERON:0004270 lower leg connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004270 A portion of connective tissue that is part of a lower leg [Automatically generated definition]. UBERON:0004277 eye muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004277 A muscle that is part of the eye region. GO:0019618 protocatechuate catabolic process, ortho-cleavage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019618 MetaCyc:PROTOCATECHUATE-ORTHO-CLEAVAGE-PWY 3,4-dihydroxybenzoate catabolic process, ortho-cleavage|protocatechuate degradation, ortho-cleavage|protocatechuate breakdown, ortho-cleavage|protocatechuate catabolic process to beta-ketoadipate The chemical reactions and pathways resulting in the breakdown of protocatechuate, the anion of 3,4-dihydroxybenzoic acid, to yield beta-ketoadipate. CHEBI:57440 N-ethylglycine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57440 GO:0019619 3,4-dihydroxybenzoate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019619 protocatechuate degradation|protocatechuate breakdown|protocatechuate catabolic process|protocatechuate catabolism The chemical reactions and pathways resulting in the breakdown of 3,4-dihydroxybenzoate. CHEBI:57441 2,3-diketogulonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57441 GO:0019616 catechol catabolic process, meta-cleavage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019616 MetaCyc:P183-PWY catechol degradation, meta-cleavage|catechol breakdown, meta-cleavage The chemical reactions and pathways resulting in the breakdown of catechol via the meta-cleavage pathway, in which the catechol aromatic ring is broken between a hydroxylated carbon atom and an adjacent unsubstituted carbon atom. GO:0019617 protocatechuate catabolic process, meta-cleavage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019617 MetaCyc:P184-PWY protocatechuate breakdown, meta-cleavage|protocatechuate degradation, meta-cleavage|3,4-dihydroxybenzoate catabolic process, meta-cleavage|protocatechuate catabolic process to oxaloacetate and pyruvate The chemical reactions and pathways resulting in the breakdown of protocatechuate, the anion of 3,4-dihydroxybenzoic acid, to yield oxaloacetate and pyruvate. GO:0019614 catechol-containing compound catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019614 catechol catabolic process|catechol catabolism|catechol degradation|catechol breakdown The chemical reactions and pathways resulting in the breakdown of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent. GO:0019615 catechol catabolic process, ortho-cleavage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019615 MetaCyc:CATECHOL-ORTHO-CLEAVAGE-PWY catechol breakdown, ortho-cleavage|catechol degradation, ortho-cleavage The chemical reactions and pathways resulting in the breakdown of catechol via the ortho-cleavage pathway, in which the catechol aromatic ring is broken between the two carbon atoms bearing hydroxyl groups. GO:0019612 4-toluenecarboxylate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019612 MetaCyc:4TOLCARBDEG-PWY 4-toluenecarboxylate breakdown|4-toluenecarboxylate catabolism|p-toluate catabolism|4-toluenecarboxylate degradation|p-toluate catabolic process The chemical reactions and pathways resulting in the breakdown of 4-toluenecarboxylate, 4-methylbenzenecarboxylate, the anion of carboxylic acid attached to a methylbenzene molecule. GO:0019613 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019613 CHEBI:57448 (5Z,9E,12S,14Z)-8,11,12-trihydroxyicosa-5,9,14-trienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57448 GO:0019610 3-hydroxyphenylacetate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019610 MetaCyc:3-HYDROXYPHENYLACETATE-DEGRADATION-PWY 3-hydroxyphenylacetate degradation|3-hydroxyphenylacetate catabolism|3-hydroxyphenylacetate breakdown The chemical reactions and pathways resulting in the breakdown of 3-hydroxyphenylacetate, 1,3-benzenediol monoacetate, also known as resorcinol monoacetate. GO:0019611 4-toluenecarboxylate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019611 4-toluenecarboxylate metabolism|p-toluate metabolism|p-toluate metabolic process The chemical reactions and pathways involving 4-toluenecarboxylate, 4-methylbenzenecarboxylate, the anion of carboxylic acid attached to a methylbenzene molecule. CHEBI:57449 (5Z,9E,14Z)-(8xi,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57449 CHEBI:57446 15(S)-HPETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57446 CHEBI:57447 8(R)-HPETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57447 CHEBI:57444 12(S)-HPETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57444 CHEBI:57445 thromboxane A2(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57445 CHEBI:57442 (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57442 CHEBI:57443 S-adenosylmethioninaminium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57443 CHEBI:57439 (3Z)-phytochromobilin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57439 CHEBI:139605 O(3)-{beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-serine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139605 CHEBI:33484 chalcogen oxoacid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33484 GO:0019629 propionate catabolic process, 2-methylcitrate cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019629 propionate breakdown, 2-methylcitrate cycle|propionate degradation, 2-methylcitrate cycle The chemical reactions and pathways resulting in the breakdown of propionate that occurs in the 2-methylcitrate cycle. CHEBI:57430 (2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57430 CHEBI:33485 chalcogen oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33485 GO:0019627 urea metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019627 urea metabolism The chemical reactions and pathways involving urea, the water soluble compound O=C-(NH2)2. CHEBI:139607 O(3)-{beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-threonine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139607 GO:0019628 urate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019628 MetaCyc:P165-PWY urate degradation|urate catabolism|urate breakdown|uric acid catabolic process The chemical reactions and pathways resulting in the breakdown of urate, the anion of uric acid, 2,6,8-trioxypurine. CHEBI:33488 selenium oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33488 GO:0019625 atrazine catabolic process to cyanuric acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019625 MetaCyc:P141-PWY atrazine breakdown to cyanuric acid|atrazine degradation to cyanuric acid The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide, into cyanuric acid. GO:0019626 short-chain fatty acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019626 MetaCyc:ACETOACETATE-DEG-PWY short-chain fatty acid degradation|short-chain fatty acid breakdown|short-chain fatty acid catabolism The chemical reactions and pathways resulting in the breakdown of fatty acids with a chain length of less than C6. CHEBI:33489 selenium oxoacid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33489 GO:0019623 atrazine catabolic process to urea biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019623 atrazine degradation to urea|atrazine breakdown to urea The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide, into urea. CHEBI:139604 beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139604 GO:0019624 atrazine catabolic process to isopropylamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019624 atrazine degradation to isopropylamine|atrazine breakdown to isopropylamine The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide, into isopropylamine. GO:0019621 creatinine catabolic process to formate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019621 MetaCyc:CRNFORCAT-PWY creatinine breakdown to formate|creatinine degradation to formate The chemical reactions and pathways resulting in the breakdown of creatinine into other compounds, including formate. CHEBI:57437 (2R,3Z)-phycocyanobilin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57437 CHEBI:57438 (3Z)-phycoerythrobilin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57438 GO:0019622 3-(3-hydroxy)phenylpropionate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019622 MetaCyc:HCAMHPDEG-PWY 3-(3-hydroxy)phenylpropionate catabolism|3-(3-hydroxy)phenylpropionate degradation|3-(3-hydroxy)phenylpropionate breakdown The chemical reactions and pathways resulting in the breakdown of 3-(3-hydroxy)phenylpropionate, a hydroxylated derivative of phenylpropionate. CHEBI:57435 (3S,4S)-3-hydroxytetradecane-1,3,4-tricarboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57435 GO:0019620 aerobic benzoate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019620 aerobic benzoate metabolism The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid) that occur in the presence of oxygen. CHEBI:57436 (3S,5S)-3,5-diammoniohexanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57436 CHEBI:139600 calcitriol 25-O-(beta-D-glucuronide) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139600 CHEBI:57433 sarcosine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57433 CHEBI:57434 (3S)-3,6-diammoniohexanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57434 CHEBI:57431 N-(ammoniomethyl)urea biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57431 CHEBI:33482 sulfur oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33482 CHEBI:57432 gibberellin A12 aldehyde(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57432 CHEBI:33483 trithionate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33483 CHEBI:57428 (3R)-beta-leucine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57428 CHEBI:57429 (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57429 CHEBI:33459 pnictogen oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33459 CHEBI:33452 benzylic group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33452 CHEBI:33455 nitrogen oxoacid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33455 CHEBI:33456 organoheteryl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33456 CHEBI:33457 phosphorus oxoacid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33457 CHEBI:33458 nitrogen oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33458 CHEBI:57426 sinapoyl (S)-malate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57426 CHEBI:57427 L-leucine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57427 CHEBI:57424 (R)-3,3-dimethylmalate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57424 CHEBI:57425 3-ethylmalate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57425 CHEBI:57422 (2R,3S)-2,3-dimethylmalate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57422 CHEBI:57423 (R)-2-ethylmalate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57423 CHEBI:57421 (2E,6E,10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57421 CHEBI:57417 2,3-dihydroxybenzoyl 5'-adenylate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57417 CHEBI:57418 (2-aminoethyl)phosphonic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57418 GO:0019609 3-hydroxyphenylacetate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019609 3-hydroxyphenylacetate metabolism|3HPA metabolic process|3HPA metabolism The chemical reactions and pathways involving 3-hydroxyphenylacetate, 1,3-benzenediol monoacetate, also known as resorcinol monoacetate. CHEBI:33462 phosphonate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33462 GO:0019607 phenylethylamine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019607 MetaCyc:2PHENDEG-PWY phenylethylamine breakdown|phenylethylamine catabolism|phenylethylamine degradation The chemical reactions and pathways resulting in the breakdown of phenylethylamine, an amine with pharmacological properties similar to those of amphetamine, occurs naturally as a neurotransmitter in the brain, and is present in chocolate and oil of bitter almonds. GO:0019608 nicotine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019608 MetaCyc:P181-PWY|UM-BBD_pathwayID:nic nicotine catabolism|nicotine degradation|nicotine breakdown The chemical reactions and pathways resulting in the breakdown of nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine. GO:0019605 butyrate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019605 butyrate metabolism|butyric acid metabolic process|butanoic acid metabolism|butanoic acid metabolic process|butyric acid metabolism The chemical reactions and pathways involving any butyrate, the anions of butyric acid (butanoic acid), a saturated, unbranched aliphatic acid. GO:0019606 2-oxobutyrate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019606 MetaCyc:2OXOBUTYRATECAT-PWY alpha-ketobutyrate catabolic process|alpha-ketobutyrate catabolism|2-oxobutyrate catabolism|2-oxobutyrate degradation|2-oxobutyrate breakdown The chemical reactions and pathways resulting in the breakdown of 2-oxobutyrate, the anion of the organic acid 2-oxobutyric acid, which contains a ketone group on carbon 2. CHEBI:33465 elemental pnictogen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33465 GO:0019603 toluene oxidation via 4-hydroxytoluene biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019603 MetaCyc:TOLUENE-DEG-4-OH-PWY The degradation of toluene to form p-hydroxybenzoate; the first step in the pathway is the oxidation of toluene to form 4-hydroxytoluene (4-cresol). GO:0019604 toluene oxidation to catechol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019604 UM-BBD_pathwayID:tol|MetaCyc:TOLUENE-DEG-CATECHOL-PWY The formation from toluene of catechol, dihydroxybenzene, by successive oxidations followed by loss of carbon dioxide (CO2). GO:0019601 toluene oxidation via 2-hydroxytoluene biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019601 MetaCyc:TOLUENE-DEG-2-OH-PWY The degradation of toluene to form pyruvate and acetaldehyde; the first step in the pathway is the oxidation of toluene to form 2-hydroxytoluene (o-cresol). GO:0019602 toluene oxidation via 3-hydroxytoluene biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019602 MetaCyc:TOLUENE-DEG-3-OH-PWY The degradation of toluene to form pyruvate and acetaldehyde; the first step in the pathway is the oxidation of toluene to form 3-hydroxytoluene (m-cresol). CHEBI:57415 N-(carboxylatoaminomethyl)urea biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57415 CHEBI:57416 D-alanine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57416 GO:0019600 toluene oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019600 The chemical reactions and pathways resulting in the loss of electrons from one or more atoms in toluene. CHEBI:57413 (1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57413 CHEBI:57414 (1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57414 CHEBI:57411 (15Z)-12-oxophyto-10,15-dienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57411 CHEBI:57412 (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57412 CHEBI:57410 15-oxo-ETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57410 CHEBI:33461 phosphorus oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33461 RO:0002091 starts during biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002091 RO:0002091 RO:0002092 happens during biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002092 RO:0002092 RO:0002093 ends_during biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002093 RO:0002093 NCBITaxon:1329799 Archelosauria organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_1329799 Archosauria-Testudines|Testudines + Archosauria group CHEBI:57408 15-dehydro-prostaglandin D2(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57408 CHEBI:57409 15(S)-HETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57409 UBERON:0004219 urethra smooth muscle layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004219 muscular layer of urethra|tunica muscularis urethrae|muscular coat of urethra|smooth muscle tissue of urethra|muscle layer of urethra|urethral smooth muscle|smooth muscle of urethra|urethra smooth muscle tissue A portion of smooth muscle tissue that is part of a urethra [Automatically generated definition]. CHEBI:57406 prostaglandin D2(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57406 RO:0002090 immediately_precedes biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002090 RO:0002090 CHEBI:57407 15-dehydro-prostaglandin I2(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57407 CHEBI:33437 chlorine oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33437 UBERON:0004220 large intestine smooth muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004220 smooth muscle tissue of large intestine|smooth muscle of large intestine|non-striated muscle of large intestine|large intestine involuntary muscle|large intestine non-striated muscle|involuntary muscle of large intestine|large intestine smooth muscle tissue A portion of smooth muscle tissue that is part of a large intestine [Automatically generated definition]. UBERON:0004221 intestine smooth muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004221 non-striated muscle of intestine|intestine smooth muscle tissue|bowel non-striated muscle|bowel smooth muscle|involuntary muscle of bowel|bowel smooth muscle tissue|intestine non-striated muscle|intestine involuntary muscle|involuntary muscle of intestine|smooth muscle tissue of bowel|smooth muscle of bowel|intestinal smooth muscle|bowel involuntary muscle|non-striated muscle of bowel|smooth muscle tissue of intestine|intestinal muscularis|smooth muscle of intestine A portion of smooth muscle tissue that is part of a intestine [Automatically generated definition]. CHEBI:33431 elemental chlorine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33431 CHEBI:33432 monoatomic chlorine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33432 CHEBI:33433 monoatomic halogen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33433 CHEBI:33434 elemental halogen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33434 UBERON:0004228 urinary bladder smooth muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004228 smooth muscle tissue of urinary bladder|smooth muscle of urinary bladder|bladder smooth muscle tissue|non-striated muscle of urinary bladder|smooth muscle tissue of bladder|urinary bladder smooth muscle tissue|smooth muscle of bladder|non-striated muscle of bladder|bladder involuntary muscle|urinary bladder non-striated muscle|urinary bladder involuntary muscle|involuntary muscle of urinary bladder|bladder non-striated muscle|bladder smooth muscle|urinary bladder muscle|involuntary muscle of bladder|smooth muscle layer of bladder A portion of smooth muscle tissue that is part of a urinary bladder [Automatically generated definition]. CHEBI:57404 prostaglandin F2alpha(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57404 CHEBI:57405 prostaglandin H2(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57405 CHEBI:57402 13,14-dihydro-15-oxo-prostaglandin E2(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57402 UBERON:0004226 gastrointestinal system smooth muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004226 smooth muscle tissue of gastrointestinal system A portion of smooth muscle tissue that is part of a digestive system [Automatically generated definition]. UBERON:0004227 kidney pelvis smooth muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004227 pelvic smooth muscle|kidney pelvis smooth muscle|smooth muscle tissue of renal pelvis|renal pelvis smooth muscle the smooth muscle tissue surrounding the urothelium of the kidney pelvis CHEBI:57403 prostaglandin I2(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57403 UBERON:0004224 muscular coat of vas deferens biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004224 muscle layer of vas deferens|tunica muscularis ductus deferentis|muscular coat of ductus deferens|muscle layer of ductus deferens|tunica muscularis (ductus deferens)|muscularis of vas deferens|muscle layer of deferent duct|muscular layer of ductus deferens A muscular coat that is part of a vas deferens [Automatically generated definition]. CHEBI:57400 15-dehydro-prostaglandin E2(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57400 CHEBI:57401 15-dehydro-prostaglandin E1(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57401 UBERON:0004225 respiratory system smooth muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004225 airway smooth muscle cell|smooth muscle of respiratory system|respiratory smooth muscle|airway smooth muscle A portion of smooth muscle tissue that is part of a respiratory system [Automatically generated definition]. UBERON:0004222 stomach smooth muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004222 smooth muscle tissue of stomach|non-striated muscle of ventriculus|smooth muscle of stomach|stomach smooth muscle tissue|gastric muscle|non-striated muscle of stomach|ventriculus smooth muscle tissue|ventriculus non-striated muscle|gastric smooth muscle|stomach involuntary muscle|ventriculus smooth muscle|stomach non-striated muscle|involuntary muscle of ventriculus|ventriculus involuntary muscle|involuntary muscle of stomach|stomach muscle|smooth muscle tissue of ventriculus|smooth muscle of ventriculus A portion of smooth muscle tissue that is part of a stomach [Automatically generated definition]. UBERON:0004223 vagina smooth muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004223 vagina involuntary muscle|non-striated muscle of vagina|vaginal smooth muscle|smooth muscle of vagina|smooth muscle tissue of vagina|vagina non-striated muscle|vagina smooth muscle tissue|vagina smooth muscle|involuntary muscle of vagina A portion of smooth muscle tissue that is part of a vagina [Automatically generated definition]. RO:0002082 simultaneous_with biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002082 RO:0002082 is_equal_to|coincides_with Relation between occurrents, shares start and end boundaries. UBERON:0004208 nephrogenic mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004208 mesenchyme of nephron|nephron mesenchyme Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron UBERON:0004209 renal vesicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004209 stage I nephron The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells. RO:0002088 during which starts biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002088 RO:0002088 RO:0002084 during which ends biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002084 RO:0002084 RO:0002085 encompasses biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002085 RO:0002085 RO:0002086 ends after biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002086 RO:0002086 RO:0002087 immediately_preceded_by biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002087 RO:0002087 is directly preceded by|is immediately preceded by|starts_at_end_of|directly preceded by X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y) CHEBI:33443 halogen oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33443 CHEBI:33447 phospho sugar biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33447 UBERON:0004217 upper arm nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004217 A nerve that is part of a forelimb stylopod [Automatically generated definition]. UBERON:0004218 lower leg nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004218 A nerve that is part of a lower leg [Automatically generated definition]. UBERON:0004215 back nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004215 nerve of back A nerve that is part of a back [Automatically generated definition]. UBERON:0004216 lower arm nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004216 A nerve that is part of a lower arm [Automatically generated definition]. UBERON:0004214 upper leg nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004214 hindlimb stylopod nerve|thigh RELATED|lower extremity stylopod nerve|hind limb stylopod nerve A nerve that is part of a hindlimb stylopod [Automatically generated definition]. UBERON:0004211 nephron epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004211 nephron epithelial tissue|epithelium of nephron|epithelial tissue of nephron The nephron epithelium is a tissue that covers the surface of a nephron UBERON:0004212 glomerular capillary biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004212 capillary vessel of renal glomerulus|renal glomerulus blood capillary|renal glomerulus capillary vessel|glomerular capillaries|glomerular capillary system|capillary of renal glomerulus|blood capillary of renal glomerulus|renal glomerulus capillary the small branching blood vessels in the kidney glomerulus that receives blood from the kidney afferent arterioles; these capillaries are under high pressure for filtering within the glomerulus CHEBI:33415 elemental carbon biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33415 CHEBI:33419 monoatomic carbon biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33419 CHEBI:33410 arsonite(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33410 CHEBI:33412 diatomic sulfur biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33412 UBERON:0004206 long descending thin limb bend biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004206 The long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment UBERON:0004207 prebend segment of loop of Henle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004207 prebend segment The prebend segment is a part of the descending thin limb that lies before the bend and exhibits robust sodium chloride reabsorption UBERON:0004204 outer medullary collecting duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004204 kidney outer medulla collecting duct|outer renal medulla collecting duct The outer medullary collecting duct is the portion of the collecting duct that lies in the renal outer medulla UBERON:0004205 inner medullary collecting duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004205 inner renal medulla collecting duct|kidney inner medulla collecting duct|papillary collecting duct The inner medullary collecting duct is the portion of the collecting duct that lies in the renal inner medulla UBERON:0004202 kidney outer medulla outer stripe biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004202 outer medulla outer stripe|outer stripe of outer medulla|stria externa medullae renalis|outer stripe|outer stripe of renal medulla|outer stripe of medulla of kidney The outer stripe is the region of the kidney that lies distal to the line of termination of the straight renal tubules UBERON:0004203 cortical collecting duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004203 renal cortex collecting duct|kidney cortex collecting duct The cortical collecting duct is the portion of the collecting duct that resides in the renal cortex UBERON:0004200 kidney pyramid biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004200 renal pyramid|Malpighian pyramid|Malphigian pyramid|pyramid of Malphigi|Malpighian pyramid|pyramides renales|pyramid of Malpighi|medullary pyramid|renal medullary region|pyramis renalis|pyramid Kidney pyramids are the conical arrangements of tubules that constitute the renal medulla in a multi-lobed mammalian kidney; they contain the loops of Henle and the medullary collecting ducts. UBERON:0004201 kidney outer medulla inner stripe biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004201 inner stripe of renal medulla|inner stripe of medulla of kidney|inner stripe|inner stripe of outer medulla|stria interna medullae renalis|outer medulla inner stripe The inner stripe is a deep, centrally located portion of the renal outer medulla and is traversed by thick and thin portions of nephron tubules CHEBI:33426 chlorine oxoacid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33426 CHEBI:33429 monoatomic monoanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33429 NCBITaxon:6072 Eumetazoa organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_6072 NCBITaxon:6073 Cnidaria organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_6073 Coelenterata|cnidarians|cnidarians|coelenterates CHEBI:33420 diatomic carbon biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33420 CHEBI:33423 monoatomic hexacation biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33423 CHEBI:33424 sulfur oxoacid derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33424 CHEBI:33425 halogen oxoacid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33425 RO:0002170 connected to biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002170 RO:0002170 Binary relationship: x connected_to y if and only if there exists some z such that z connects x and y in a ternary connected_to(x,y,z) relationship. GO:0030138 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030138 GO:0030139 endocytic vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030139 NIF_Subcellular:sao1362520468 endocytotic transport vesicle|endocytotic vesicle A membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance. Endocytic vesicles fuse with early endosomes to deliver the cargo for further sorting. GO:0030136 clathrin-coated vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030136 NIF_Subcellular:sao148845161 A vesicle with a coat formed of clathrin connected to the membrane via one of the clathrin adaptor complexes. GO:0030137 COPI-coated vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030137 coatomer A vesicle with a coat formed of the COPI coat complex proteins. COPI-coated vesicles are found associated with Golgi membranes at steady state, are involved in Golgi to endoplasmic reticulum (retrograde) vesicle transport, and possibly also in intra-Golgi transport. GO:0044786 cell cycle DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044786 The DNA-dependent DNA replication that takes place as part of the cell cycle. GO:0005178 integrin binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0005178 integrin ligand Interacting selectively and non-covalently with an integrin. RO:0002176 connects biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002176 RO:0002176 Binary relationship: z connects x if and only if there exists some y such that z connects x and y in a ternary connected_to(x,y,z) relationship. GO:0005179 hormone activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0005179 lipopeptide hormone|peptide hormone|glycopeptide hormone|cAMP generating peptide activity The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects; all bind receptors and trigger some biological process. RO:0002177 attaches_to_part_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002177 RO:0002177 GO:0044787 bacterial-type DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044787 bacterial-type cell cycle DNA replication The DNA-dependent DNA replication, exemplified by prokaryotes, that occurs as part of the cell cycle. Prokaryotic DNA replication is bi-directional and originates at a single origin of replication on the circular genome. CHEBI:140675 3-hydroxyacyl derivative of bacterial toxin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140675 RO:0002178 supplies biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002178 RO:0002178 arterial supply of relation between an artery and the structure is supplies with blood. GO:0044784 metaphase/anaphase transition of cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044784 The cell cycle process in which a cell progresses from metaphase to anaphase as part of the cell cycle. GO:0005176 ErbB-2 class receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005176 Neu receptor ligand|HER2 receptor ligand|HER2 receptor binding|Neu receptor binding|ErbB-2 class receptor ligand Interacting selectively and non-covalently with the protein-tyrosine kinase receptor Neu/ErbB-2/HER2. RO:0002179 drains biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002179 RO:0002179 drains from|drains blood from GO:0044785 metaphase/anaphase transition of meiotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044785 meiotic metaphase/anaphase transition The cell cycle process in which a cell progresses from metaphase to anaphase as part of meiosis. GO:0005177 obsolete neuroligin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005177 neuroligin OBSOLETE. A class of ligands for neurexins. GO:0044782 cilium organization biolink:BiologicalProcess go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0044782 microtubule-based flagellum organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole. GO:0005174 CD40 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005174 Interacting selectively and non-covalently with CD40, a receptor found on the surface of all B-lymphocytes. GO:0005175 CD27 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005175 Interacting selectively and non-covalently with a CD27, a receptor found on the surface of T cells and some B cells and NK cells. GO:0044783 G1 DNA damage checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044783 G1/S DNA damage checkpoint A cell cycle checkpoint that detects and negatively regulates progression from G1 to S phase in the cell cycle in response to DNA damage. PATO:0002309 fiber shaped biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PATO_0002309 A convex 3-D shape quality inhering in a bearer by virtue of the bearer's exhibiting a by virtue of the bearer's exhibiting a consistently sized and approximately round cross-section along its length, which is many times larger than its diameter. GO:0044780 bacterial-type flagellum assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044780 bacterial flagellum assembly The assembly of a bacterial-type flagellum, a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope which functions in cell motility. GO:0005172 vascular endothelial growth factor receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005172 vascular endothelial growth factor|VEGF receptor binding|VEGFR binding|vascular endothelial growth factor receptor ligand Interacting selectively and non-covalently with any vascular endothelial growth factor receptor. GO:0005173 stem cell factor receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005173 SCF|stem cell factor|stem cell factor receptor ligand|KIT binding|SCFR binding Interacting selectively and non-covalently with the stem cell factor receptor (SCFR), a type III transmembrane kinase receptor. GO:0044781 bacterial-type flagellum organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044781 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a bacterial-type flagellum, a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope which functions in cell motility. GO:0005181 obsolete glycopeptide hormone biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005181 glycopeptide hormone OBSOLETE. (Was not defined before being made obsolete). GO:0005182 obsolete lipopeptide hormone biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005182 lipopeptide hormone OBSOLETE. (Was not defined before being made obsolete). GO:0005180 obsolete peptide hormone biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005180 peptide hormone OBSOLETE. (Was not defined before being made obsolete). CHEBI:140678 4,4-dihydroxy-all-trans-beta-carotene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140678 GO:0044788 modulation by host of viral process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044788 A process in which a host organism modulates the frequency, rate or extent of any of a process being mediated by a virus with which it is infected. CHEBI:140676 4',4'-dihydroxyechinenone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140676 GO:0044789 modulation by host of viral release from host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044789 A process in which a host organism modulates the frequency, rate or extent of the release of a virus with which it is infected, from its cells. CHEBI:140677 4-hydroxy-all-trans-beta-carotene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140677 GO:0030134 COPII-coated ER to Golgi transport vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030134 COPII-associated vesicle|COPII-associated ER to Golgi transport vesicle|endoplasmic reticulum-Golgi transport vesicle|ER to Golgi constitutive secretory pathway transport vesicle|ER-Golgi transport vesicle|COPII-coated vesicle|COPII vesicle|ER to Golgi transport vesicle|endoplasmic reticulum to Golgi transport vesicle A vesicle with a coat formed of the COPII coat complex proteins. The COPII coat complex is formed by the Sec23p/Sec24p and the Sec13p/Sec31p heterodimers. COPII-associated vesicles transport proteins from the rough endoplasmic reticulum to the Golgi apparatus (anterograde transport). GO:0030135 coated vesicle biolink:CellularComponent go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0030135 NIF_Subcellular:sao1985096626 Small membrane-bounded organelle formed by pinching off of a coated region of membrane. Some coats are made of clathrin, whereas others are made from other proteins. GO:0030132 clathrin coat of coated pit biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030132 The coat found on coated pits and the coated vesicles derived from coated pits; comprises clathrin and the AP-2 adaptor complex. GO:0030133 transport vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030133 NIF_Subcellular:sao885490876 Golgi-vacuole transport vesicle|Golgi to vacuole transport vesicle|constitutive secretory pathway transport vesicle|secretory vesicle Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell. GO:0030130 clathrin coat of trans-Golgi network vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030130 clathrin coat of TGN vesicle A clathrin coat found on a vesicle of the trans-Golgi network. GO:0030131 clathrin adaptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030131 A membrane coat adaptor complex that links clathrin to a membrane. GO:0044790 negative regulation by host of viral release from host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044790 A process in which a host organism stops, prevents or reduces the frequency, rate or extent of the release of a virus with which it is infected, from its cells. GO:0030129 clathrin coat of synaptic vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030129 A clathrin coat found on a synaptic vesicle. RO:0002160 only in taxon biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002160 RO:0002160 never_outside_taxon|specific_to_taxon|specific_to x only in taxon y if and only if x is in taxon y, and there is no other organism z such that y!=z a and x is in taxon z. GO:0030127 COPII vesicle coat biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030127 One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state. GO:0030128 clathrin coat of endocytic vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030128 clathrin coat of endocytotic vesicle A clathrin coat found on an endocytic vesicle. GO:0030125 clathrin vesicle coat biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030125 A clathrin coat found on a vesicle. GO:0030126 COPI vesicle coat biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030126 coatomer One of two multimeric complexes that forms a membrane vesicle coat. The mammalian COPI subunits are called alpha-, beta-, beta'-, gamma-, delta-, epsilon- and zeta-COP. Vesicles with COPI coats are found associated with Golgi membranes at steady state. CHEBI:140663 N(2)-[(3R)-3-(acyloxy)acyl]-L-ornithine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140663 GO:0005189 obsolete milk protein biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005189 milk protein OBSOLETE. (Was not defined before being made obsolete). GO:0044797 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044797 CHEBI:140664 S-(2-sulfodisulfanyl)-L-cysteine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140664 GO:0044798 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044798 GO:0044795 trans-Golgi network to recycling endosome transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044795 The directed movement of substances, in membrane-bounded vesicles, from the trans-Golgi network to the recycling endosomes. GO:0005187 obsolete storage protein biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005187 storage protein OBSOLETE. (Was not defined before being made obsolete). CHEBI:140662 2,4-diacetylphloroglucinol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140662 GO:0044796 DNA polymerase processivity factor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044796 A protein complex which is capable of increasing the processivity of nucleotide polymerization by DNA polymerase as a part of DNA replication. GO:0005188 obsolete larval serum protein (sensu Insecta) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005188 arylphorin|larval serum protein (sensu Insecta) OBSOLETE. (Was not defined before being made obsolete). GO:0044793 negative regulation by host of viral process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044793 A process in which a host organism stops, prevents or reduces the frequency, rate or extent of a process being mediated by a virus with which it is infected. RO:0002161 never_in_taxon biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002161 x never in taxon T if and only if T is a class, and x does not instantiate the class expression "in taxon some T". Note that this is a shortcut relation, and should be used as a hasValue restriction in OWL. GO:0005185 neurohypophyseal hormone activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005185 neurohypophysial hormone activity The action characteristic of a neurohypophyseal hormone, any of a family of structurally and functionally related nonapeptides that are synthesized as part of a larger precursor molecule comprising a signal peptide, the nonapeptide hormone, and a neurophysin. GO:0044794 positive regulation by host of viral process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044794 A process in which a host organism activates or increases the frequency, rate or extent of the release of a process being mediated by a virus with which it is infected. GO:0005186 pheromone activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005186 The activity of binding to and activating specific cell surface receptors, thereby inducing behavioral, developmental, or physiological response(s) from a responding organism or cell. The substance may be released or retained on the cell surface. Pheromones may serve as a specific attractant, social communicator, or sexual stimulant. RO:0002162 in taxon biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002162 RO:0002162 x is in taxon y if an only if y is an organism, and the relationship between x and y is one of: part of (reflexive), developmentally preceded by, derives from, secreted by, expressed. CHEBI:140660 a 2-acyl-sn-glycero-3-phospholipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140660 GO:0005183 gonadotropin hormone-releasing hormone activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005183 LH/FSH-RF|GnRH activity|luteinizing hormone-releasing factor activity|gonadotrophin hormone-releasing hormone activity|luteinizing hormone/follicle-stimulating hormone releasing factor activity|luteinizing hormone-releasing hormone activity|LHRH activity The action characteristic of gonadotropin hormone-releasing hormone (GnRH), any of a family of decapeptide amide hormones that are released by the hypothalamus in response to neural and/or chemical stimuli. In at least mammals, upon receptor binding, GnRH causes the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) by the anterior pituitary. GO:0044791 positive regulation by host of viral release from host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044791 A process in which a host organism activates or increases the frequency, rate or extent of the release of a virus with which it is infected, from its cells. RO:0002163 spatially disjoint from biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002163 RO:0002163 A is spatially_disjoint_from B if and only if they have no parts in common GO:0005184 neuropeptide hormone activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0005184 Wikipedia:Neurohormone neurohormone The action characteristic of a neuropeptide hormone, any peptide hormone that acts in the central nervous system. A neuropeptide is any of several types of molecules found in brain tissue, composed of short chains of amino acids; they include endorphins, enkephalins, vasopressin, and others. They are often localized in axon terminals at synapses and are classified as putative neurotransmitters, although some are also hormones. PATO:0002318 superelliptic biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PATO_0002318 Lamé curve A shape constituting a transition between a rectangle and a circle; a closed curve, of which the circle and ellipse are special cases, whose parametric equation is x = a.cos2/rt, y = b.cos2/rt GO:0044792 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044792 CHEBI:57396 vinylacetyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57396 GO:0005192 obsolete urinary protein biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005192 urinary protein OBSOLETE. (Was not defined before being made obsolete). CHEBI:57397 prostaglandin E1(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57397 GO:0005193 obsolete major urinary protein biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005193 major urinary protein OBSOLETE. (Was not defined before being made obsolete). GO:0005190 obsolete seminal fluid protein biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005190 seminal fluid protein OBSOLETE. (Was not defined before being made obsolete). CHEBI:57394 stearoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57394 CHEBI:57395 thiophene-2-carbonyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57395 GO:0005191 obsolete acidic epididymal glycoprotein biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005191 acidic epididymal glycoprotein OBSOLETE. (Was not defined before being made obsolete). CHEBI:57392 propionyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57392 GOP:syngo_official_label label approved by the SynGO project biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/go#syngo_official_label RO:0002158 homologous_to biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002158 RO:0002158 CHEBI:57393 sinapoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57393 RO:0002159 serially_homologous_to biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002159 RO:0002159 GO:0044799 NarGHI complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044799 nitrate reductase A|cytoplasmic membrane-bound quinol-nitrate oxidoreductase A heterotrimeric protein complex with iron-sulfur and molybdenum cofactors that functions as a terminal reductase in electron transport pathways that operate during anaerobic nitrate respiration. In E. coli electrons are passed from the FdnGHI complex to the NarGHI complex via menoquinone and menaquinol. Within NarGHI, electrons are passed from the two heme molecules in the NarI subunit down a Fe-S cluster chain in the NarH and NarG subunits to the Molybdenum cofactor, Mo-bisMGD, in the NarG subunit. CHEBI:57390 phenylacetyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57390 CHEBI:57391 phytanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57391 GO:0030123 AP-3 adaptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030123 A heterotetrameric AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes. AP-3 does not appear to associate with clathrin in all organisms. In at least humans, the AP-3 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (beta3A and beta3B, mu3A and mu3B, and sigma3A and sigma3B). GO:0030124 AP-4 adaptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030124 An AP-type membrane coat adaptor complex that consists of beta4, epsilon, mu4 and sigma4 subunits and is found associated with membranes in the trans-Golgi network; it is not clear whether AP-4 forms clathrin coats in vivo. GO:0030121 AP-1 adaptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030121 AP-1 related adapter complex|HA1|HA1 clathrin adaptor A heterotetrameric AP-type membrane coat adaptor complex that consists of beta1, gamma, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle; vesicles with AP-1-containing coats are normally found primarily in the trans-Golgi network. In at least humans, the AP-1 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (gamma1 and gamma2, mu1A and mu1B, and sigma1A, sigma1B and sigma1C). GO:0030122 AP-2 adaptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030122 HA2|HA2 clathrin adaptor A heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits, and links clathrin to the membrane surface of a vesicle, and the cargo receptors during receptor/clathrin mediated endocytosis. Vesicles with AP-2-containing coats are normally found primarily near the plasma membrane, on endocytic vesicles. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC). GO:0030120 vesicle coat biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030120 NIF_Subcellular:sao1177708494 A membrane coat found on a coated vesicle. CHEBI:57398 prostaglandin A1(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57398 CHEBI:57399 prostaglandin C1(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57399 GO:0030118 clathrin coat biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030118 Wikipedia:Clathrin|NIF_Subcellular:sao879919129 clathrin cage A membrane coat found on coated pits and some coated vesicles; consists of polymerized clathrin triskelions, each comprising three clathrin heavy chains and three clathrin light chains, linked to the membrane via one of the AP adaptor complexes. GO:0030119 AP-type membrane coat adaptor complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0030119 clathrin adaptor Any of several heterotetrameric complexes that link clathrin (or another coat-forming molecule, as hypothesized for AP-3 and AP-4) to a membrane surface; they are found on coated pits and coated vesicles, and mediate sorting of cargo proteins into vesicles. Each AP complex contains two large (a beta and one of either an alpha, gamma, delta, or epsilon) subunits (110-130 kDa), a medium (mu) subunit (approximately 50 kDa), and a small (sigma) subunit (15-20 kDa). GO:0030116 glial cell-derived neurotrophic factor receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030116 glial cell line-derived neurotrophic factor receptor ligand|glial cell line-derived neurotrophic factor receptor binding A growth factor that binds selectively and non-covalently to glial cell-derived neurotrophic factor receptors. GO:0030117 membrane coat biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030117 Any of several different proteinaceous coats that can associate with membranes. Membrane coats include those formed by clathrin plus an adaptor complex, the COPI and COPII complexes, and possibly others. They are found associated with membranes on many vesicles as well as other membrane features such as pits and perhaps tubules. GO:0005158 insulin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005158 insulin receptor ligand Interacting selectively and non-covalently with the insulin receptor. GO:0030114 slime layer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030114 Wikipedia:Slime_layer A slime layer is an easily removed, diffuse, unorganized layer of extracellular material that surrounds a cell. Specifically this consists mostly of exopolysaccharides, glycoproteins, and glycolipids. GO:0030115 S-layer biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0030115 Wikipedia:S-layer A crystalline protein layer surrounding some bacteria. GO:0005159 insulin-like growth factor receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005159 IGF receptor binding|insulin-like growth factor receptor ligand|insulin-like growth factor Interacting selectively and non-covalently with the insulin-like growth factor receptor. CHEBI:140652 (2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140652 GO:0005156 obsolete epidermal growth factor receptor inhibiting ligand activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005156 EGFR inhibiting ligand activity|epidermal growth factor receptor inhibiting ligand activity|EGF receptor inhibiting ligand activity OBSOLETE. This term was not defined before being made obsolete. GO:0005157 macrophage colony-stimulating factor receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005157 macrophage colony-stimulating factor receptor ligand|M-CSF receptor binding|macrophage colony stimulating factor receptor binding Interacting selectively and non-covalently with the macrophage colony-stimulating factor receptor. CHEBI:140650 4-[(E)-2-isocyanoethenyl]phenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140650 GO:0005154 epidermal growth factor receptor binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0005154 transforming growth factor alpha|TGF-alpha receptor binding|EGF receptor binding|EGF receptor ligand|TGFalpha receptor binding|EGFR binding|transforming growth factor alpha receptor ligand|epidermal growth factor|EGF|transforming growth factor alpha receptor binding|epidermal growth factor receptor ligand Interacting selectively and non-covalently with the epidermal growth factor receptor. GO:0005155 obsolete epidermal growth factor receptor activating ligand activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005155 EGF receptor activating ligand activity|EGFR activating ligand activity|epidermal growth factor receptor activating ligand activity OBSOLETE. This term was not defined before being made obsolete. RO:0002150 continuous_with biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002150 RO:0002150 GO:0005152 interleukin-1 receptor antagonist activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005152 IL-1ra Blocks the binding of interleukin-1 to the interleukin-1 receptor complex. GO:0005153 interleukin-8 receptor binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0005153 IL-8|interleukin-8 receptor ligand Interacting selectively and non-covalently with the interleukin-8 receptor. GO:0005150 interleukin-1, type I receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005150 interleukin-1, type I receptor ligand|IL-1 type I Interacting selectively and non-covalently with a Type I interleukin-1 receptor. GO:0005151 interleukin-1, type II receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005151 interleukin-1, type II receptor ligand|IL-1 type II Interacting selectively and non-covalently with a Type II interleukin-1 receptor. CHEBI:57385 myristoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57385 GO:0005160 transforming growth factor beta receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005160 transforming growth factor beta receptor ligand|activin|TGFbeta receptor binding|inhibin|transforming growth factor beta|TGF-beta receptor binding|transforming growth factor beta ligand binding to type II receptor|transforming growth factor beta receptor anchoring activity|transforming growth factor beta ligand binding to type I receptor Interacting selectively and non-covalently with the transforming growth factor beta receptor. CHEBI:57386 octanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57386 CHEBI:57383 linoleoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57383 CHEBI:140658 S-1,2-diacyl-sn-glyceryl-L-cysteine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140658 CHEBI:57384 malonyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57384 CHEBI:57381 itaconyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57381 CHEBI:140656 N-terminal S-1,2-diacyl-sn-glyceryl-L-cysteine(1+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140656 CHEBI:57382 lactoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57382 CHEBI:140657 N-acyl-S-1,2-diacyl-sn-glyceryl-L-cysteine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140657 GO:0019799 tubulin N-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019799 EC:2.3.1.108|RHEA:15277|MetaCyc:TUBULIN-N-ACETYLTRANSFERASE-RXN tubulin acetyltransferase activity|TAT activity|acetyl-CoA:alpha-tubulin-lysine N-acetyltransferase activity|alpha-tubulin acetyltransferase activity|alpha-tubulin N-acetyltransferase activity|acetyl-CoA:alpha-tubulin-L-lysine 6-N-acetyltransferase activity|acetyl-CoA:alpha-tubulin-L-lysine N6-acetyltransferase activity|alpha-tubulin acetylase activity Catalysis of the reaction: acetyl-CoA + (alpha-tubulin) L-lysine = CoA + (alpha-tubulin) N6-acetyl-L-lysine. CHEBI:140654 3-[(E)-2-isocyanovinyl]indole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140654 CHEBI:57380 icosanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57380 CHEBI:140655 16alpha-hydroxy-beta-amyrin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140655 GO:0019797 procollagen-proline 3-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019797 KEGG_REACTION:R03218|MetaCyc:PROCOLLAGEN-PROLINE-3-DIOXYGENASE-RXN|RHEA:22872|Reactome:R-HSA-1980233|EC:1.14.11.7 proline,2-oxoglutarate 3-dioxygenase activity|procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity|procollagen-proline,2-oxoglutarate 3-dioxygenase activity|prolyl 3-hydroxylase activity|protocollagen proline 3-hydroxylase activity|prolyl-4-hydroxyprolyl-glycyl-peptide, 2-oxoglutarate: oxygen oxidoreductase, 3-hydroxylating activity Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-3-hydroxy-L-proline + succinate + CO2. GO:0030112 glycocalyx biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0030112 Wikipedia:Glycocalyx A carbohydrate rich layer at the outermost periphery of a cell. GO:0030113 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030113 GO:0019798 procollagen-proline dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019798 Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-hydroxy-L-proline + succinate + CO2. GO:0019795 obsolete nonprotein amino acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019795 nonprotein amino acid biosynthesis|nonprotein amino acid biosynthetic process|nonprotein amino acid anabolism|nonprotein amino acid synthesis|nonprotein amino acid formation OBSOLETE. The chemical reactions and pathways resulting in the formation of any amino acid that does not normally occur as a constituent residue of proteins. GO:0030110 HLA-C specific inhibitory MHC class I receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030110 Combining with a MHC class I molecule of the HLA-C subclass to mediate signaling that inhibits activation of a lymphocyte. GO:0030111 regulation of Wnt signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030111 regulation of Wnt-activated signaling pathway|regulation of frizzled signalling pathway|regulation of frizzled signaling pathway|regulation of Wnt receptor signalling pathway|regulation of Wnt receptor signaling pathway Any process that modulates the frequency, rate or extent of the activity of the Wnt signal transduction pathway. GO:0019796 obsolete nonprotein amino acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019796 nonprotein amino acid degradation|nonprotein amino acid breakdown|nonprotein amino acid catabolism|nonprotein amino acid catabolic process OBSOLETE. The chemical reactions and pathways resulting in the breakdown of any amino acid not found, or rarely found, in peptide linkage in proteins. CHEBI:57389 pentanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57389 GO:0019793 obsolete ISG15 carrier activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019793 interferon-stimulated gene-15 carrier activity|ISG15 carrier activity OBSOLETE. Catalysis of the transfer of ISG15 (interferon-stimulated gene-15) from one side of the membrane to the other. GO:0019794 obsolete nonprotein amino acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019794 nonprotein amino acid metabolic process|nonprotein amino acid metabolism OBSOLETE. The chemical reactions and pathways involving any amino acid not found, or rarely found, in peptide linkage in proteins. CHEBI:57387 oleoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57387 GO:0019791 obsolete FAT10 hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019791 FAT10 hydrolase activity OBSOLETE. (Was not defined before being made obsolete). CHEBI:57388 oxalyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57388 GO:0019792 obsolete APG12 hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019792 APG12 hydrolase activity OBSOLETE. (Was not defined before being made obsolete). GO:0030109 HLA-B specific inhibitory MHC class I receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030109 Combining with a MHC class I molecule of the HLA-B subclass to mediate signaling that inhibits activation of a lymphocyte. GO:0030107 HLA-A specific inhibitory MHC class I receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030107 Combining with a MHC class I molecule of the HLA-A subclass to mediate signaling that inhibits activation of a lymphocyte. GO:0030108 HLA-A specific activating MHC class I receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030108 Combining with a MHC class I molecule of the HLA-A subclass to mediate signaling that activates a lymphocyte. GO:0030105 obsolete anaphylaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030105 anaphylaxis OBSOLETE. Extreme immunological sensitivity of the body or tissues to the reintroduction of an antigen. It is a form of anamnestic reaction and is accompanied by pathological changes in tissues or organs due to the release of pharmacologically active substances. GO:0030106 obsolete MHC class I receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030106 major histocompatibility complex class I receptor|MHC class I receptor activity|class I major histocompatibility complex antigen OBSOLETE. A major histocompatibility complex class I receptor. These display processed antigens from the endocytosed bacteria. MHC class I proteins can form complexes with processed antigen peptides only if the antigen is synthesized in the same cell. As a consequence, T lymphocytes can only bind to class-I-positive cells that are synthesizing the antigen (e.g. virus-infected cells). GO:0030103 vasopressin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030103 The regulated release of vasopressin from secretory granules into the blood. GO:0005169 neurotrophin TRKB receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005169 neurotrophin TRKB receptor ligand Interacting selectively and non-covalently with the neurotrophin TRKB receptor. GO:0030104 water homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030104 Wikipedia:Osmoregulation regulation of osmotic pressure|osmoregulation Any process involved in the maintenance of an internal steady state of water within an organism or cell. CHEBI:140641 rhizobitoxine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140641 GO:0005167 neurotrophin TRK receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005167 neurotrophin TRK receptor ligand Interacting selectively and non-covalently with a neurotrophin TRK receptor. CHEBI:140642 dihydrorhizobitoxine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140642 GO:0005168 neurotrophin TRKA receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005168 neurotrophin TRKA receptor ligand Interacting selectively and non-covalently with the neurotrophin TRKA receptor. GO:0005165 neurotrophin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005165 neurotrophin receptor ligand|neurotrophin Interacting selectively and non-covalently with a neurotrophin receptor. CHEBI:140640 dihydroferuloyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140640 GO:0005166 neurotrophin p75 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005166 neurotrophin p75 receptor ligand Interacting selectively and non-covalently with the neurotrophin p75 receptor. GO:0005163 nerve growth factor receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005163 nerve growth factor receptor ligand|neurotrophin|NGF receptor binding Interacting selectively and non-covalently with the nerve growth factor receptor. GO:0005164 tumor necrosis factor receptor binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0005164 tumor necrosis factor|tumor necrosis factor receptor ligand|TNF receptor binding Interacting selectively and non-covalently with the tumor necrosis factor receptor. GO:0005161 platelet-derived growth factor receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005161 PDGF receptor binding|PDGFR binding|platelet-derived growth factor|PDGF|platelet-derived growth factor receptor ligand Interacting selectively and non-covalently with the platelet-derived growth factor receptor. GO:0005162 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005162 GO:0005170 neurotrophin TRKC receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005170 neurotrophin TRKC receptor ligand Interacting selectively and non-covalently with the neurotrophin TRKC receptor. CHEBI:57374 cyclohexa-1,5-diene-1-carbonyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57374 GO:0005171 hepatocyte growth factor receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005171 HGF receptor binding|hepatocyte growth factor receptor ligand|hepatocyte growth factor Interacting selectively and non-covalently with the hepatocyte growth factor receptor. CHEBI:57375 lauroyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57375 CHEBI:57372 caffeoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57372 CHEBI:140647 (2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140647 CHEBI:140648 (2E)-3-(4-hydroxyphenyl)-2-isocyanoprop-2-enoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140648 CHEBI:57373 choloyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57373 CHEBI:57370 biotinyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57370 CHEBI:140646 poly(2,5-ethylene furandicarboxylate)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140646 CHEBI:57371 butyryl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57371 GO:0030101 natural killer cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030101 NK cell activation The change in morphology and behavior of a natural killer cell in response to a cytokine, chemokine, cellular ligand, or soluble factor. GO:0030102 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030102 GO:0030100 regulation of endocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030100 Any process that modulates the frequency, rate or extent of endocytosis. CHEBI:57378 glutaryl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57378 CHEBI:57379 palmitoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57379 CHEBI:57376 formyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57376 CHEBI:57377 cis-geranoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57377 GO:0005138 interleukin-6 receptor binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0005138 IL-6|interleukin-6 receptor ligand Interacting selectively and non-covalently with the interleukin-6 receptor. GO:0005139 interleukin-7 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005139 IL-7|interleukin-7 receptor ligand Interacting selectively and non-covalently with the interleukin-7 receptor. GO:0005136 interleukin-4 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005136 IL-4|interleukin-4 receptor ligand Interacting selectively and non-covalently with the interleukin-4 receptor. GO:0005137 interleukin-5 receptor binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0005137 IL-5|interleukin-5 receptor ligand Interacting selectively and non-covalently with the interleukin-5 receptor. GO:0005134 interleukin-2 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005134 IL-2|interleukin-2 receptor ligand Interacting selectively and non-covalently with the interleukin-2 receptor. GO:0005135 interleukin-3 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005135 IL-3|interleukin-3 receptor ligand Interacting selectively and non-covalently with the interleukin-3 receptor. RO:0002134 innervates biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002134 RO:0002134 GO:0005132 type I interferon receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005132 interferon-alpha/beta receptor binding|interferon-alpha/beta|IFNAR2 binding|IFNAR1 binding|IFNAR binding|interferon-alpha/beta receptor ligand Interacting selectively and non-covalently with an interferon-type I receptor, a heterodimeric complex composed of an alpha subunit (IFNAR1) and a beta subunit (IFNAR2). GO:0005133 interferon-gamma receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005133 interferon-gamma|interferon-gamma receptor ligand Interacting selectively and non-covalently with the interferon-gamma receptor. GO:0005130 granulocyte colony-stimulating factor receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005130 G-CSF receptor ligand|granulocyte colony-stimulating factor|granulocyte colony stimulating factor receptor binding|GC-SF receptor ligand|granulocyte colony-stimulating factor receptor ligand Interacting selectively and non-covalently with the granulocyte colony-stimulating factor receptor. GO:0005131 growth hormone receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005131 growth hormone receptor ligand|growth hormone Interacting selectively and non-covalently with the growth hormone receptor. RO:0002131 overlaps biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002131 RO:0002131 A overlaps B if they share some part in common. CHEBI:57363 gamma-linolenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57363 CHEBI:140638 7beta-hydroxy-3-oxochol-4-en-24-oyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140638 CHEBI:57364 4-(2-carboxyphenyl)-4-oxobutanoyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57364 CHEBI:140639 dihydro-4-coumaroyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140639 CHEBI:140636 7alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140636 CHEBI:57361 6-hydroxycyclohex-1-ene-1-carbonyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57361 CHEBI:57362 beta-alanyl-CoA(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57362 CHEBI:140637 7beta-hydroxy-3-oxochol-24-oyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140637 GO:0019779 Atg8 activating enzyme activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019779 APG8 activating enzyme activity|APG7 Catalysis of the activation of the small ubiquitin-related modifier APG8, through the formation of an ATP-dependent high-energy thiolester bond. CHEBI:140634 3-oxochol-4,6-dien-24-oyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140634 CHEBI:57360 pimeloyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57360 CHEBI:140635 12alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140635 GO:0019777 Atg12 transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019777 Reactome:R-HSA-5681999 APG12 ligase activity|APG12 conjugating enzyme activity|Atg12 ligase activity|Atg12 conjugating enzyme activity Catalysis of the transfer of ATG12 from one protein to another via the reaction X-ATG12 + Y --> Y-ATG12 + X, where both X-ATG12 and Y-ATG12 are covalent linkages. CHEBI:140632 5-methylaminomethyl-S-(2E)-geranyl-thiouridine 5'-monophosphate zwitterion residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140632 CHEBI:140633 5-formyl-3-hydroxy-2-methylpyridine-4-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140633 GO:0019778 Atg12 activating enzyme activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019778 APG12 activating enzyme activity Catalysis of the activation of the small ubiquitin-related modifier APG12, through the formation of an ATP-dependent high-energy thiolester bond. GO:0019775 FAT10 transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019775 FAT10 conjugating enzyme activity Catalysis of the transfer of FAT10 from one protein to another via the reaction X-FAT10 + Y --> Y-FAT10 + X, where both X-FAT10 and Y-FAT10 are covalent linkages. GO:0019776 Atg8 ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019776 Reactome:R-HSA-5681981 Atg8 conjugating enzyme activity|APG8 ligase activity|APG8 conjugating enzyme activity Catalysis of the covalent attachment of the ubiquitin-like protein Atg8 to substrate molecules; phosphatidylethanolamine is a known substrate. CHEBI:57369 benzoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57369 GO:0019773 proteasome core complex, alpha-subunit complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019773 The proteasome core subcomplex that constitutes the two outer rings of the proteasome core complex. An example of this component is found in Mus musculus. GO:0019774 proteasome core complex, beta-subunit complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019774 The proteasome core subcomplex that constitutes the two inner rings of the proteasome core complex. An example of this component is found in Mus musculus. GO:0019771 high-affinity IgG receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019771 high affinity Fc receptor activity|high affinity IgG receptor activity Combining with high affinity with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. CHEBI:57367 acryloyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57367 CHEBI:57368 arachidonoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57368 GO:0019772 low-affinity IgG receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019772 low affinity IgG receptor activity|low affinity Fc receptor activity Combining with low affinity with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. CHEBI:57365 5-hydroxy-2-furoyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57365 CHEBI:57366 L-3-aminobutanoyl-CoA(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57366 GO:0019770 IgG receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019770 Combining with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0019790 obsolete ubiquitin-like hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019790 ubiquitin-like hydrolase activity OBSOLETE. (Was not defined before being made obsolete). GO:0005149 interleukin-1 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005149 IL-1|interleukin-1 receptor ligand Interacting selectively and non-covalently with the interleukin-1 receptor. GO:0005147 oncostatin-M receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005147 oncostatin-M|oncostatin-M receptor ligand Interacting selectively and non-covalently with the oncostatin-M receptor. GO:0005148 prolactin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005148 prolactin receptor ligand|prolactin Interacting selectively and non-covalently with the prolactin receptor. GO:0005145 interleukin-14 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005145 IL-14|interleukin-14 receptor ligand Interacting selectively and non-covalently with the interleukin-14 receptor. GO:0005146 leukemia inhibitory factor receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005146 leukemia inhibitory factor|leukemia inhibitory factor receptor ligand Interacting selectively and non-covalently with the leukemia inhibitory factor receptor. CHEBI:140620 alpha-D-galactosyl-(1->4)-N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140620 GO:0005143 interleukin-12 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005143 IL-12|interleukin-12 receptor ligand Interacting selectively and non-covalently with the interleukin-12 receptor. GO:0005144 interleukin-13 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005144 IL-13|interleukin-13 receptor ligand Interacting selectively and non-covalently with the interleukin-13 receptor. GO:0005141 interleukin-10 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005141 interleukin-10 receptor ligand|IL-10 Interacting selectively and non-covalently with the interleukin-10 receptor. GO:0005142 interleukin-11 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005142 interleukin-11 receptor ligand|IL-11 Interacting selectively and non-covalently with the interleukin-11 receptor. GO:0005140 interleukin-9 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005140 interleukin-9 receptor ligand|IL-9 Interacting selectively and non-covalently with the interleukin-9 receptor. RO:0002120 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002120 RO:0002120 CHEBI:140627 RNA(n)-3'-uridine ribonucleotide polyanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140627 CHEBI:57352 4-aminobutanoyl-CoA(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57352 CHEBI:57353 trans-4-carboxybut-2-enoyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57353 CHEBI:140625 5-chlorocarbonyl-4-hydroxy-penta-2,4-dienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140625 CHEBI:57350 3-oxopimeloyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57350 CHEBI:140626 RNA(n)-3'-adenine ribonucleotide polyanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140626 CHEBI:57351 4,8,12-trimethyltridecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57351 CHEBI:140623 Monosialyl-Gb5(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140623 CHEBI:140624 Disialosyl Gb5(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140624 GO:0019788 NEDD8 transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019788 Reactome:R-HSA-8951661|Reactome:R-HSA-8952618|Reactome:R-HSA-8951648|Reactome:R-HSA-8956025|Reactome:R-HSA-8952638|Reactome:R-HSA-8952044|Reactome:R-HSA-8951764 NEDD8 conjugating enzyme activity|Hub1 conjugating enzyme activity|RUB1 conjugating enzyme activity Catalysis of the transfer of NEDD8 from one protein to another via the reaction X-NEDD8 + Y --> Y-NEDD8 + X, where both X-NEDD8 and Y-NEDD8 are covalent linkages. GO:0019789 SUMO transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019789 Reactome:R-HSA-4551724|Reactome:R-HSA-3900177|Reactome:R-HSA-4641342|Reactome:R-HSA-4755479|Reactome:R-HSA-3108209|Reactome:R-HSA-4090408|Reactome:R-HSA-5228521|Reactome:R-HSA-4551604|Reactome:R-HSA-2997706|Reactome:R-HSA-4551661|Reactome:R-HSA-5684052|Reactome:R-HSA-3927824|Reactome:R-HSA-4568914|Reactome:R-HSA-3900070|Reactome:R-HSA-4551648|Reactome:R-HSA-3232162|Reactome:R-HSA-4551679|Reactome:R-HSA-5228525|Reactome:R-HSA-4341070|Reactome:R-HSA-4755536|Reactome:R-HSA-2997723|Reactome:R-HSA-4570499|Reactome:R-HSA-3000449|Reactome:R-HSA-6790454|Reactome:R-HSA-4090284|Reactome:R-HSA-4755478|Reactome:R-HSA-3968362|Reactome:R-HSA-4717461|Reactome:R-HSA-4086083|Reactome:R-HSA-4551727|Reactome:R-HSA-2997709|Reactome:R-HSA-3000434|Reactome:R-HSA-4086036|Reactome:R-HSA-4656914|Reactome:R-HSA-4551738|Reactome:R-HSA-4655431|Reactome:R-HSA-4719436|Reactome:R-HSA-4570496|Reactome:R-HSA-3899291|Reactome:R-HSA-4570467|Reactome:R-HSA-4570554|Reactome:R-HSA-4085372|Reactome:R-HSA-4570489|Reactome:R-HSA-4551768|Reactome:R-HSA-4570528|Reactome:R-HSA-4719413|Reactome:R-HSA-4085318|Reactome:R-HSA-3234094|Reactome:R-HSA-4570485|Reactome:R-HSA-3234084|Reactome:R-HSA-3900047|Reactome:R-HSA-4719447|Reactome:R-HSA-4086088|Reactome:R-HSA-4551721|Reactome:R-HSA-4655440|Reactome:R-HSA-3968414|Reactome:R-HSA-4655355|Reactome:R-HSA-3108203|Reactome:R-HSA-4546387|Reactome:R-HSA-3000348|Reactome:R-HSA-4551616|Reactome:R-HSA-4090390|Reactome:R-HSA-4570493|Reactome:R-HSA-3234081|Reactome:R-HSA-4086059|Reactome:R-HSA-4615889|Reactome:R-HSA-4615910|Reactome:R-HSA-5682607|Reactome:R-HSA-4719423|Reactome:R-HSA-4615905|Reactome:R-HSA-3296126|Reactome:R-HSA-4085994|Reactome:R-HSA-4755526|Reactome:R-HSA-3927886|Reactome:R-HSA-4720432|Reactome:R-HSA-4085992|Reactome:R-HSA-3000399|Reactome:R-HSA-4085350|Reactome:R-HSA-3000433|Reactome:R-HSA-4568863|Reactome:R-HSA-4719448|Reactome:R-HSA-4570553|Reactome:R-HSA-4720446|Reactome:R-HSA-4755411|Reactome:R-HSA-5228523|Reactome:R-HSA-5228508|Reactome:R-HSA-4090281|Reactome:R-HSA-2997616|Reactome:R-HSA-2993769|Reactome:R-HSA-4568848|Reactome:R-HSA-4341073|Reactome:R-HSA-4616015|Reactome:R-HSA-4551655|Reactome:R-HSA-4641350|Reactome:R-HSA-6804485|Reactome:R-HSA-4546386|Reactome:R-HSA-4568846|Reactome:R-HSA-4090288|Reactome:R-HSA-4755494|Reactome:R-HSA-4615900|Reactome:R-HSA-4085296|Reactome:R-HSA-3000411|Reactome:R-HSA-4546385|Reactome:R-HSA-3782535|Reactome:R-HSA-6804468|Reactome:R-HSA-4341025|Reactome:R-HSA-4615839|Reactome:R-HSA-3108212|Reactome:R-HSA-4615933|Reactome:R-HSA-4615872|Reactome:R-HSA-4551683|Reactome:R-HSA-4341016|Reactome:R-HSA-4085347|Reactome:R-HSA-4655374|Reactome:R-HSA-3465545|Reactome:R-HSA-3247493|Reactome:R-HSA-8956365|Reactome:R-HSA-4341048|Reactome:R-HSA-4615873|Reactome:R-HSA-3927959|Reactome:R-HSA-4641345|Reactome:R-HSA-4641362|Reactome:R-HSA-4717521|Reactome:R-HSA-4615987|Reactome:R-HSA-4341072|Reactome:R-HSA-4085331|Reactome:R-HSA-2993780|Reactome:R-HSA-4719424|Reactome:R-HSA-3903017|Reactome:R-HSA-3000383|Reactome:R-HSA-3900194|Reactome:R-HSA-2993790|Reactome:R-HSA-4551649|Reactome:R-HSA-4570463 SUMO conjugating enzyme activity|SMT3 conjugating enzyme Catalysis of the transfer of SUMO from one protein to another via the reaction X-SUMO + Y --> Y-SUMO + X, where both X-SUMO and Y-SUMO are covalent linkages. GO:0019786 Atg8-specific protease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019786 APG8-PE hydrolase|APG8-specific protease activity Catalysis of the hydrolysis of APG8, a small ubiquitin-related modifier. GO:0019787 ubiquitin-like protein transferase activity biolink:MolecularActivity go-plus goslim_drosophila|goslim_pir http://purl.obolibrary.org/obo/GO_0019787 Reactome:R-HSA-688137|Reactome:R-HSA-5678490 small conjugating protein ligase activity|ubiquitin-like conjugating enzyme activity|E3|small conjugating protein transferase activity|ubiquitin-like-protein ligase activity|small protein conjugating enzyme activity|E2 Catalysis of the transfer of a ubiquitin-like from one protein to another via the reaction X-ULP + Y --> Y-ULP + X, where both X-ULP and Y-ULP are covalent linkages. ULP represents a ubiquitin-like protein. GO:0019784 NEDD8-specific protease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019784 Reactome:R-HSA-8863723|Reactome:R-HSA-8956040|Reactome:R-HSA-5690808|Reactome:R-HSA-8956045 deneddylase activity Catalysis of the hydrolysis of NEDD8, a small ubiquitin-related modifier, from previously neddylated substrates. CHEBI:57358 5-hydroxythiophene-2-carbonyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57358 GO:0019785 ISG15-specific protease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019785 Reactome:R-HSA-5653786|Reactome:R-HSA-1678841 Catalysis of the hydrolysis of ISG15, a small ubiquitin-related modifier, from previously modified substrates. CHEBI:57359 2,3-didehydropimeloyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57359 GO:0019782 ISG15 activating enzyme activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019782 UBE1L Catalysis of the activation of the small ubiquitin-related modifier ISG15, through the formation of an ATP-dependent high-energy thiolester bond. CHEBI:57356 4-hydroxybenzoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57356 GO:0019783 ubiquitin-like protein-specific protease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019783 ubiquitin-specific protease activity involved in positive regulation of ERAD pathway|ubiquitin-like specific protease activity|ubiquitin-like-protein-specific protease activity|small conjugating protein-specific protease activity|ubiquitin-specific protease activity involved in negative regulation of ERAD pathway Catalysis of the hydrolysis of peptide or isopeptide bonds within small proteins such as ubiquitin or ubiquitin-like proteins (e.g. APG8, ISG15, NEDD8, SUMO), or between the small protein and a larger protein to which it has been conjugated. CHEBI:57357 5-hydroxypentanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57357 CHEBI:140629 dialurate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140629 CHEBI:57354 4-chlorobenzoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57354 GO:0019780 FAT10 activating enzyme activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019780 Catalysis of the activation of the small ubiquitin-related modifier FAT10, through the formation of an ATP-dependent high-energy thiolester bond. GO:0019781 NEDD8 activating enzyme activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019781 RUB1 activating enzyme activity Catalysis of the initiation of the NEDD8 (RUB1) conjugation cascade. CHEBI:57355 4-coumaroyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57355 GO:0005118 sevenless binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005118 sev binding|sev ligand|sevenless ligand Interacting selectively and non-covalently with the sevenless (sev) protein, a receptor tyrosine kinase. GO:0005119 smoothened binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005119 smo ligand|smoothened ligand|smo binding Interacting selectively and non-covalently with the smoothened (smo) protein, which interacts with patched to transmit hedgehog signals. GO:0005116 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005116 GO:0005117 wishful thinking binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005117 Wit binding|wishful thinking ligand|SE20 receptor binding|Wit ligand Interacting selectively and non-covalently with wishful thinking (Wit), a type II bone morphogenic protein receptor. GO:0005114 type II transforming growth factor beta receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005114 type II TGF-beta binding|punt ligand|transforming growth factor beta ligand binding to type II receptor|punt binding|TGF-beta type II binding|transforming growth factor beta receptor type II binding Interacting selectively and non-covalently with a type II transforming growth factor beta receptor. GO:0005115 receptor tyrosine kinase-like orphan receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005115 receptor tyrosine kinase-like orphan receptor ligand|Ror ligand|Ror binding Interacting selectively and non-covalently with the receptor tyrosine kinase-like orphan receptor (Ror). GO:0005112 Notch binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005112 Notch receptor binding|N ligand|Notch ligand|N binding Interacting selectively and non-covalently with the Notch (N) protein, a surface receptor. GO:0005113 patched binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005113 ptc binding|ptc ligand|patched ligand Interacting selectively and non-covalently with the patched (ptc) protein, a receptor for hedgehog proteins. GO:0005110 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005110 GO:0005111 type 2 fibroblast growth factor receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005111 heartless binding|heartless ligand|type 2 fibroblast growth factor receptor ligand|FGFR2 ligand|FGFR2 binding Interacting selectively and non-covalently with the type 2 fibroblast growth factor receptor (FGFR2). CHEBI:57341 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57341 CHEBI:140616 N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-Ceramide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140616 CHEBI:140617 N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140617 CHEBI:57342 3-hydroxybenzoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57342 CHEBI:140614 alpha-D-galactosyl-(1->4)-N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-Ceramide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140614 GO:0019759 glycosinolate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019759 glycosinolate catabolism|glycosinolate degradation|glycosinolate breakdown The chemical reactions and pathways resulting in the breakdown of glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae. CHEBI:57340 3-hydroxy-2-methylpropanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57340 CHEBI:140615 alpha-D-galactosyl-(1->4)-N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140615 CHEBI:139612 O(3)-{N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-threonine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139612 GO:0019757 glycosinolate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019757 glycosinolate metabolism The chemical reactions and pathways involving glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae. RO:0002103 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002103 RO:0002103 CHEBI:140613 L,L-homocystine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140613 GO:0019758 glycosinolate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019758 glycosinolate anabolism|glycosinolate synthesis|glycosinolate biosynthesis|glycosinolate formation The chemical reactions and pathways resulting in the formation of glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae. RO:0002104 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002104 RO:0002104 CHEBI:139613 calcidiol 3-O-(beta-D-glucuronide) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139613 GO:0019755 one-carbon compound transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019755 one carbon compound transport The directed movement of one-carbon compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:140610 4'-hydroxyechinenone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140610 GO:0019756 cyanogenic glycoside biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019756 cyanogenic glycoside biosynthesis|cyanogenic glycoside anabolism|cyanogenic glycoside synthesis|cyanogenic glycoside formation The chemical reactions and pathways resulting in the formation of cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits. GO:0019753 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019753 CHEBI:57349 3-oxopalmitoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57349 GO:0019754 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019754 CHEBI:139610 calcidiol 25-O-(beta-D-glucuronide) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139610 GO:0019751 polyol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019751 polyhydric alcohol metabolic process|polyol metabolism The chemical reactions and pathways involving a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms. CHEBI:57347 3-oxo-fatty acyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57347 GO:0019752 carboxylic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019752 carboxylic acid metabolism The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-). CHEBI:57348 3-oxoadipyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57348 CHEBI:139611 O(3)-{beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->3)-[beta-D-GlcNAc-(1->6)]-alpha-D-GalNAc}-L-serine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139611 CHEBI:57345 isovaleryl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57345 GO:0019750 chloroplast localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019750 chloroplast localisation Any process in which a chloroplast is transported to, and/or maintained in, a specific location within the cell. A chloroplast is a chlorophyll-containing plastid found in cells of algae and higher plants. CHEBI:57346 trans-3-methylglutaconyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57346 CHEBI:57343 3-hydroxypimeloyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57343 CHEBI:57344 3-methylbut-2-enoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57344 CHEBI:140619 alpha-D-galactosyl-(1->4)-N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140619 GO:0005129 granulocyte macrophage colony-stimulating factor receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005129 granulocyte macrophage colony-stimulating factor receptor ligand|GMC-SF receptor ligand|GM-CSF receptor binding|granulocyte macrophage colony stimulating factor receptor binding|granulocyte macrophage colony-stimulating factor|GM-CSF receptor ligand Interacting selectively and non-covalently with the granulocyte macrophage colony-stimulating factor receptor. GO:0005127 ciliary neurotrophic factor receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005127 ciliary neurotrophic factor|ciliary neurotrophic factor receptor ligand Interacting selectively and non-covalently with the ciliary neurotrophic factor receptor. GO:0005128 erythropoietin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005128 erythropoietin receptor ligand|erythropoietin Interacting selectively and non-covalently with the erythropoietin receptor. GO:0005125 cytokine activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0005125 paracrine activity|autocrine activity The activity of a soluble extracellular gene product that interacts with a receptor to effect a change in the activity of the receptor to control the survival, growth, differentiation and effector function of tissues and cells. GO:0005126 cytokine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005126 hematopoietin/interferon-class (D200-domain) cytokine receptor ligand|hematopoietin/interferon-class (D200-domain) cytokine receptor binding Interacting selectively and non-covalently with a cytokine receptor. GO:0005123 death receptor binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0005123 death receptor interacting protein activity|EDAR binding|DR binding|KILLER binding|TNFR1 binding|death receptor ligand|TRAIL binding|NGFR binding|death receptor-associated factor activity|APO binding|FAS binding|death receptor adaptor protein activity Interacting selectively and non-covalently with any member of the death receptor (DR) family. The DR family falls within the tumor necrosis factor receptor superfamily and is characterized by a cytoplasmic region of ~80 residues termed the death domain (DD). GO:0005124 scavenger receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005124 scavenger receptor ligand Interacting selectively and non-covalently with scavenger receptors, a family of proteins that are expressed on myeloid cells and are involved in the uptake of effete cellular components and foreign particles. RO:0002100 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002100 RO:0002100 GO:0005121 Toll binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005121 Toll receptor binding|Tl binding|Toll ligand Interacting selectively and non-covalently with the Toll protein, a transmembrane receptor. GO:0005122 torso binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005122 torso ligand|tor binding|tor ligand Interacting selectively and non-covalently with the torso (tor) protein, a receptor tyrosine kinase. RO:0002102 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002102 RO:0002102 GO:0005120 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005120 CHEBI:57330 trans-dodec-2-enoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57330 CHEBI:140605 tetrahydrosulfopterin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140605 CHEBI:140606 5,10-methylenetetrahydrosulfopterin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140606 CHEBI:57331 anthraniloyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57331 CHEBI:140603 3-acetamido-4-hydroxybenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_140603 CHEBI:140604 heparan sulfate alpha-D-glucosaminide 6-sulfate polyanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140604 GO:0019768 high-affinity IgE receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019768 high affinity Fc receptor activity|high affinity IgE receptor activity Combining with high affinity with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. CHEBI:140601 fatty acid 4:0 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_140601 GO:0019769 low-affinity IgE receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019769 low affinity Fc receptor activity|low affinity IgE receptor activity Combining with low affinity with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0019766 IgA receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019766 Combining with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0019767 IgE receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019767 Combining with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. CHEBI:140600 alpha-D-xylose-(1->3)-alpha-D-xylose-(1->3)-beta-D-glucose-L-threonyl residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140600 GO:0019764 obsolete high affinity Fc receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019764 high affinity Fc receptor activity OBSOLETE. (Was not defined before being made obsolete). CHEBI:57338 isobutyryl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57338 GO:0019765 obsolete low affinity Fc receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019765 low affinity Fc receptor activity OBSOLETE. (Was not defined before being made obsolete). CHEBI:57339 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57339 GO:0019762 glucosinolate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019762 MetaCyc:PWY-5267 glucosinolate degradation|glucosinolate breakdown|glucosinolate catabolism The chemical reactions and pathways resulting in the breakdown of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae. CHEBI:57336 2-methylbutanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57336 GO:0019763 immunoglobulin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019763 FC receptor activity Combining with the Fc region of an immunoglobulin protein and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. CHEBI:57337 2-methylcrotonoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57337 GO:0019760 glucosinolate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019760 glucosinolate metabolism The chemical reactions and pathways involving glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae. They are metabolized to a variety of toxic products which are most likely the cause of hepatocytic necrosis in animals and humans. CHEBI:57334 2-hydroxyphytanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57334 GO:0019761 glucosinolate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019761 glucosinolate biosynthesis|glucosinolate anabolism|glucosinolate synthesis|glucosinolate formation The chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae. CHEBI:57335 2-methylacetoacetyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57335 CHEBI:140607 S-(ADP-D-ribosyl)-L-cysteine(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140607 CHEBI:57332 crotonoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57332 CHEBI:33384 L-serine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33384 CHEBI:57333 2-furoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57333 CHEBI:72960 N-dodecanoylsphingosine 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72960 CHEBI:72961 N-octadecanoylsphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72961 CHEBI:72962 N-icosanoylsphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72962 CHEBI:72963 N-hexadecanoylsphingosine 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72963 CHEBI:72965 N-tetracosanoylsphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72965 GO:0044706 multi-multicellular organism process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044706 A multicellular organism process which involves another multicellular organism of the same or different species. GO:0044707 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044707 GO:0044704 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044704 GO:0044705 multi-organism reproductive behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044705 The specific behavior of an organism that is associated with reproduction involving another organism of the same or different species. GO:0044702 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044702 GO:0044703 multi-organism reproductive process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044703 A biological process that directly contributes to the process of producing new individuals, involving another organism. GO:0044700 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044700 GO:0044701 obsolete response to stimulus by single organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044701 response to stimulus by single organism OBSOLETE. A response to a stimulus that involves only one organism. GO:0044708 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044708 GO:0044709 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044709 GO:0044710 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044710 GO:0044717 8-hydroxy-dADP phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044717 Reactome:R-HSA-2395965 Catalysis of the reaction: 8-hydroxy-dADP + H2O = 8-hydroxy-dAMP + phosphate. GO:0044718 siderophore transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044718 siderophore membrane transport The directed movement of siderophores, low molecular weight Fe(III)-chelating substances, from one side of a membrane to the other, by means of some agent such as a transporter or pore. GO:0044715 8-oxo-dGDP phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044715 Reactome:R-HSA-2395879|Reactome:R-HSA-2395873|EC:3.6.1.58|RHEA:32063 Catalysis of the reaction 8-oxo-dGDP + H2O = 8-oxo-dGMP + phosphate. GO:0044716 8-oxo-GDP phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044716 RHEA:62356|EC:3.6.1.58 Catalysis of the reaction 8-oxo-GDP + H2O = 8-oxo-GMP + phosphate. GO:0044713 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044713 GO:0044714 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044714 GO:0044711 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044711 GO:0044712 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044712 GO:0044719 regulation of imaginal disc-derived wing size biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044719 Any process that modulates the size of an imaginal disc-derived wing. GO:0044720 negative regulation of imaginal disc-derived wing size biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044720 Any process that reduces the size of an imaginal disc-derived wing. GO:0044721 protein import into peroxisome matrix, substrate release biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044721 The process by which the cargo protein is released into the peroxisomal matrix, following translocation across the membrane. GO:0044728 DNA methylation or demethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044728 changes in DNA methylation The process of adding or removing a methyl group from one or more nucleotides within an DNA molecule. GO:0030192 obsolete Hsp70/Hsc70 protein regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030192 Hsp70/Hsc70 protein regulator activity OBSOLETE. Modulates the activity of chaperones of the Hsp70/Hsc70 class. GO:0044729 hemi-methylated DNA-binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044729 double-stranded hemi-methylated DNA binding Interacting selectively and non-covalently with double-stranded hemi-methylated DNA at replication foci (one strand methylated, while the other strand is unmethylated). Methylation of cytosine or adenine in DNA is an important mechanism for establishing stable heritable epigenetic marks. GO:0030193 regulation of blood coagulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030193 Any process that modulates the frequency, rate or extent of blood coagulation. GO:0044726 protection of DNA demethylation of female pronucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044726 The protection of the maternal genome from DNA demethylation in the zygote following fertilization. GO:0030190 obsolete chaperone inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030190 chaperone inhibitor activity OBSOLETE. Stops, prevents or reduces the activity of a molecular chaperone. GO:0044727 DNA demethylation of male pronucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044727 The active DNA demethylation of the paternal genome that takes place before the first cell division. GO:0030191 obsolete Hsp70/Hsc70 protein inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030191 Hsp70/Hsc70 protein inhibitor activity OBSOLETE. Stops, prevents or reduces the activity of chaperones of the Hsp70/Hsc70 class. GO:0044724 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044724 GO:0044725 chromatin reprogramming in the zygote biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044725 The global reprogramming of epigenetic modifications in the zygote following fertilization. The paternal genome undergoes active DNA demethylation before the first cell division, while the adjacent maternal genome is protected from this process. GO:0044722 renal phosphate excretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044722 renal phosphate ion excretion The elimination by an organism of phosphate ions in the urine. GO:0044723 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044723 GO:0030198 extracellular matrix organization biolink:BiologicalProcess go-plus goslim_generic|goslim_chembl http://purl.obolibrary.org/obo/GO_0030198 extracellular matrix organization and biogenesis|extracellular matrix organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix. GO:0030199 collagen fibril organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030199 collagen fibril organisation|fibrillar collagen organization Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix. GO:0030196 cyanide hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030196 KEGG_REACTION:R01408|EC:4.2.1.66|RHEA:21720|MetaCyc:CYANIDE-HYDRATASE-RXN formamide hydro-lyase (cyanide-forming)|formamide dehydratase activity|formamide hydro-lyase activity Catalysis of the reaction: formamide = H(2)O + hydrogen cyanide. GO:0030197 extracellular matrix constituent, lubricant activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030197 core matrisome|core extracellular matrix Functions as a lubricant for an extracellular matrix, such as a mucous membrane. GO:0030194 positive regulation of blood coagulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030194 upregulation of blood coagulation|up regulation of blood coagulation|activation of blood coagulation|stimulation of blood coagulation|up-regulation of blood coagulation Any process that activates or increases the frequency, rate or extent of blood coagulation. GO:0030195 negative regulation of blood coagulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030195 down regulation of blood coagulation|downregulation of blood coagulation|down-regulation of blood coagulation|inhibition of blood coagulation Any process that stops, prevents, or reduces the frequency, rate or extent of blood coagulation. CHEBI:72998 1-hexadecanoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72998 CHEBI:72999 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72999 GO:0044731 Ost-alpha/Ost-beta complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044731 (Ost)2 complex|SLC51 complex|Ost alpha-Ost beta complex A heterodimeric protein complex composed of Ost-alpha/SLC51A and Ost-beta/SLC51B subunits and involved in bile acid transport activity. GO:0044732 mitotic spindle pole body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044732 The microtubule organizing center that forms as part of the mitotic cell cycle; functionally homologous to the animal cell centrosome. GO:0044730 bone sialoprotein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044730 InterPro:IPR008412 bone sialoprotein II binding Interacting selectively and non-covalently with a bone sialoprotein, an extracellular matrix glycoprotein found on the surface of bones and dentin. GO:0030181 obsolete sodium:calcium exchange biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030181 sodium:calcium exchange OBSOLETE. Exchange diffusion sodium and calcium ions in which influx of sodium ions to the cytosol drives the efflux of calcium ions from the cell. GO:0044739 positive regulation of acid-sensing ion channel in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044739 positive regulation of ASIC channel in other organism Any process in which an organism positively regulates the activity of a voltage-gated sodium channel in another organism. GO:0030182 neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030182 The process in which a relatively unspecialized cell acquires specialized features of a neuron. GO:0044737 modulation of acid-sensing ion channel in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044737 regulation of ASIC channel in other organism|regulation of acid-sensing ion channel in other organism Any process in which an organism effects a change in the frequency, rate or extent of the activity of an acid-sensing ion channel (ASIC) in another organism. GO:0030180 obsolete solute:solute exchange biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030180 solute:solute exchange OBSOLETE. Exchange diffusion of two solutes between the inside and outside of a cell or subcellular compartment, in which movement of one solute down a concentration gradient drives movement of the other solute in the opposite direction. GO:0044738 negative regulation of acid-sensing ion channel in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044738 negative regulation of ASIC channel in other organism Any process in which an organism negatively regulates the activity of a voltage-gated sodium channel in another organism. GO:0044735 envenomation resulting in negative regulation of acid-sensing ion channel activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044735 envenomation resulting in negative regulation of ASIC channel activity in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant negative regulation in the activity of an acid-sensing ion channel (ASIC) in the bitten organism. GO:0044736 acid-sensing ion channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044736 Reactome:R-HSA-2671885|Wikipedia:Acid-sensing_ion_channel ASIC activity Enables the transmembrane transfer of a sodium ion by a neuronal, voltage-insensitive channel that opens when an extracellular proton has been bound by the channel complex. GO:0044733 envenomation resulting in modulation of acid-sensing ion channel activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044733 envenomation resulting in modulation of ASIC channel activity in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of an acid-sensing ion channel (ASIC) in the bitten organism. GO:0044734 envenomation resulting in positive regulation of acid-sensing ion channel activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044734 envenomation resulting in positive regulation of ASIC channel activity in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant positive regulation in the activity of an acid-sensing ion channel (ASIC) in the bitten organism. GO:0030189 obsolete chaperone activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030189 chaperone activator activity OBSOLETE. Increases the activity of a molecular chaperone. GO:0030187 melatonin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030187 melatonin anabolism|melatonin biosynthesis|melatonin synthesis|melatonin formation The chemical reactions and pathways resulting in the formation of melatonin (N-acetyl-5-methoxytryptamine). GO:0030188 obsolete chaperone regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030188 chaperone regulator activity OBSOLETE. Modulates the activity of a molecular chaperone. GO:0030185 nitric oxide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030185 The directed movement of nitric oxide, nitrogen monoxide, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0030186 melatonin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030186 melatonin metabolism The chemical reactions and pathways involving melatonin (N-acetyl-5-methoxytryptamine). CHEBI:72990 3''-deamino-3''-hydroxykanamycin B biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72990 GO:0030183 B cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030183 B-lymphocyte differentiation|B cell development|B lymphocyte differentiation|B-cell differentiation The process in which a precursor cell type acquires the specialized features of a B cell. A B cell is a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity. CHEBI:72991 dihydrourocanate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72991 GO:0030184 nitric oxide transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030184 Enables the transfer of nitric oxide, nitrogen monoxide, from one side of a membrane to the other. CHEBI:72992 3''-deamino-3''-hydroxykanamycin X biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72992 GO:0044742 envenomation resulting in modulation of sensory perception of pain in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044742 envenomation resulting in regulation of sensory perception of pain in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the modulation of the sensory perception of pain in the bitten organism. GO:0044743 protein transmembrane import into intracellular organelle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044743 The directed movement of proteins into an intracellular organelle, across a membrane. GO:0044740 negative regulation of sensory perception of pain in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044740 inhibition of sensory perception of pain in another organism A process that negatively regulates the sensory perception of pain in a different organism. GO:0044741 envenomation resulting in negative regulation of sensory perception of pain in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044741 envenomation resulting in inhibition of sensory perception of pain in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the inhibition of the sensory perception of pain in the bitten organism. GO:0030170 pyridoxal phosphate binding biolink:MolecularActivity go-plus goslim_metagenomics http://purl.obolibrary.org/obo/GO_0030170 Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6. GO:0030171 voltage-gated proton channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030171 voltage gated proton channel activity|voltage-dependent proton channel activity Enables the transmembrane transfer of a proton by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. GO:0044748 3'-5'-exoribonuclease activity involved in mature miRNA 3'-end processing biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044748 exonucleolytic trimming to generate 3' end of miRNA Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule that contributes to forming distinct miRNA isoforms from a mature miRNA. GO:0044749 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044749 GO:0044746 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044746 GO:0044747 mature miRNA 3'-end processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044747 miRNA 3'-end processing|miRNA trimming|miRNA 3' end terminal trimming Any process involved in forming distinct miRNA isoforms from a mature miRNA that differ at their 3'-ends. GO:0044744 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044744 GO:0044745 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044745 GO:0030178 negative regulation of Wnt signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030178 down regulation of frizzled signaling pathway|negative regulation of Wnt receptor signaling pathway|down-regulation of Wnt receptor signaling pathway|inhibition of frizzled signaling pathway|negative regulation of Wnt-activated signaling pathway|negative regulation of frizzled signalling pathway|downregulation of Wnt receptor signaling pathway|down regulation of Wnt receptor signaling pathway|inhibition of Wnt receptor signaling pathway|down-regulation of frizzled signaling pathway|negative regulation of frizzled signaling pathway|negative regulation of Wnt receptor signalling pathway|downregulation of frizzled signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the Wnt signaling pathway. GO:0030179 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030179 GO:0030176 integral component of endoplasmic reticulum membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030176 integral to endoplasmic reticulum membrane|ER integral membrane protein|integral to ER membrane The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0030177 positive regulation of Wnt signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030177 positive regulation of Wnt-activated signaling pathway|positive regulation of frizzled signalling pathway|upregulation of frizzled signaling pathway|positive regulation of Wnt receptor signaling pathway|up regulation of Wnt receptor signaling pathway|stimulation of frizzled signaling pathway|up-regulation of frizzled signaling pathway|activation of frizzled signaling pathway|upregulation of Wnt receptor signaling pathway|positive regulation of Wnt receptor signalling pathway|positive regulation of frizzled signaling pathway|up regulation of frizzled signaling pathway|stimulation of Wnt receptor signaling pathway|up-regulation of Wnt receptor signaling pathway|activation of Wnt receptor signaling pathway Any process that activates or increases the frequency, rate or extent of Wnt signal transduction. GO:0030174 regulation of DNA-dependent DNA replication initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030174 DNA replication licensing|regulation of DNA replication initiation|DNA replication licencing Any process that modulates the frequency, rate or extent of initiation of DNA-dependent DNA replication; the process in which DNA becomes competent to replicate. In eukaryotes, replication competence is established in early G1 and lost during the ensuing S phase. GO:0030175 filopodium biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0030175 Wikipedia:Filopodia|NIF_Subcellular:sao1046371754 Thin, stiff, actin-based protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal or dendritic growth cone, or a dendritic shaft. GO:0030172 troponin C binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030172 Interacting selectively and non-covalently with troponin C, the calcium-binding subunit of the troponin complex. GO:0030173 integral component of Golgi membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030173 Golgi integral membrane protein|integral to Golgi membrane The component of the Golgi membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0030169 low-density lipoprotein particle binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0030169 LDL binding Interacting selectively and non-covalently with a low-density lipoprotein particle, a lipoprotein particle that is rich in cholesterol esters and low in triglycerides, is typically composed of APOB100 and APOE, and has a density of 1.02-1.06 g/ml and a diameter of between 20-25 nm. GO:0044753 amphisome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044753 Intermediate organelles formed during macroautophagy through the fusion between autophagosomes and endosomes. GO:0044754 autolysosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044754 NIF_Subcellular:sao8444068431 AVd|degrading autophagic vacuole|autophagolysosome A type of secondary lysosome in which a primary lysosome has fused with the outer membrane of an autophagosome. It is involved in the second step of autophagy in which it degrades contents with acidic lysosomal hydrolases. GO:0044751 cellular response to human chorionic gonadotropin stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044751 cellular response to human chorionic gonadotrophin stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a human chorionic gonadotropin stimulus. GO:0044752 response to human chorionic gonadotropin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044752 response to human chorionic gonadotropin stimulus Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a human chorionic gonadotropin stimulus. GO:0044750 high-affinity nickel cation transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044750 Catalysis of the high-affinity transfer of nickel (Ni) cations from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. GO:0030160 synaptic receptor adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030160 GKAP/Homer scaffold protein|postsynaptic density scaffold protein|GKAP/Homer scaffold activity The binding activity of a molecule that provides a physical support bridging a synaptic signaling receptor and a downstream signaling molecule. GO:0044759 negative regulation by symbiont of host synaptic transmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044759 Any process in which a symbiont organism decreases the frequency, rate or extent of synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse, in its host organism. GO:0044757 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044757 GO:0044758 modulation by symbiont of host synaptic transmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044758 regulation by symbiont of host synaptic transmission Any process in which a symbiont organism modulates the frequency, rate or extent of synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse, in its host organism. GO:0044755 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044755 GO:0044756 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044756 GO:0030167 proteoglycan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030167 proteoglycan degradation|proteoglycan breakdown|proteoglycan catabolism The chemical reactions and pathways resulting in the breakdown of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. GO:0030168 platelet activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030168 blood coagulation, platelet activation A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug. PR:000018461 interleukin-8 proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000018461 CXCL8/ClvPrd An interleukin-8 that has been processed by proteolytic cleavage. GO:0030165 PDZ domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030165 GLGF-domain binding|DHR-domain binding Interacting selectively and non-covalently with a PDZ domain of a protein, a domain found in diverse signaling proteins. GO:0030166 proteoglycan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030166 proteoglycan anabolism|proteoglycan synthesis|proteoglycan biosynthesis|proteoglycan formation The chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. GO:0030163 protein catabolic process biolink:BiologicalProcess go-plus goslim_candida|goslim_drosophila|goslim_aspergillus|goslim_pombe http://purl.obolibrary.org/obo/GO_0030163 Wikipedia:Protein_catabolism protein catabolism|protein degradation|pheromone catabolism|protein breakdown|multicellular organismal protein catabolic process|pheromone catabolic process The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. GO:0030164 protein denaturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030164 Wikipedia:Denaturation#Protein_denaturation Structural change in proteins which destroys the native, active configuration without rupture of peptide bonds. GO:0030161 obsolete calpain inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030161 calpain inhibitor activity OBSOLETE. Stops, prevents or reduces the activity of the enzyme calpain, which catalyzes of the preferential cleavage of Tyr-Xaa, Met-Xaa or Arg-Xaa with Leu or Val as the P2 residue. GO:0030162 regulation of proteolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030162 regulation of peptidolysis Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein. GO:0030158 protein xylosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030158 RHEA:50192|MetaCyc:2.4.2.26-RXN|Reactome:R-HSA-1878002|EC:2.4.2.26 peptide O-xylosyltransferase activity|UDP-D-xylose:proteoglycan core protein beta-D-xylosyltransferase activity|UDP-D-xylose:core protein xylosyltransferase activity|UDP-xylose-core protein beta-D-xylosyltransferase activity|uridine diphosphoxylose-protein xylosyltransferase activity|UDP-D-xylose:core protein beta-D-xylosyltransferase activity|uridine diphosphoxylose-core protein beta-xylosyltransferase activity|UDP-D-xylose:protein beta-D-xylosyltransferase activity Catalysis of the transfer of a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate. CHEBI:150018 3-aminobutanoic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_150018 GO:0030159 signaling receptor complex adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030159 receptor signaling complex adaptor activity|receptor signaling complex scaffold activity|receptor signaling complex scaffold protein activity|receptor signalling complex adaptor activity|receptor signalling complex scaffold activity The binding activity of a molecule that provides a physical support for the assembly of a multiprotein receptor signaling complex. GO:0044764 multi-organism cellular process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044764 Any process that is carried out at the cellular level which involves another organism of the same or different species. GO:0044765 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044765 GO:0044762 negative regulation by symbiont of host neurotransmitter secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044762 Any process in which a symbiont organism negatively regulates the regulated release of a neurotransmitter from a cell in its host organism. GO:0005198 structural molecule activity biolink:MolecularActivity go-plus goslim_flybase_ribbon|goslim_chembl|goslim_agr|goslim_candida|goslim_yeast|goslim_plant|goslim_pir|goslim_aspergillus|goslim_generic http://purl.obolibrary.org/obo/GO_0005198 The action of a molecule that contributes to the structural integrity of a complex or its assembly within or outside a cell. GO:0044763 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044763 GO:0005199 structural constituent of cell wall biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005199 The action of a molecule that contributes to the structural integrity of a cell wall. GO:0044760 modulation by symbiont of host cholinergic synaptic transmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044760 regulation by symbiont of host cholinergic synaptic transmission Any process in which a symbiont organism modulates the frequency, rate or extent of cholinergic synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse via the neurotransmitter choline, in its host organism. GO:0044761 negative regulation by symbiont of host cholinergic synaptic transmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044761 Any process in which a symbiont organism negatively regulates cholinergic synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse via the neurotransmitter choline, in its host organism. GO:0005194 obsolete cell adhesion molecule activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005194 cell adhesion molecule activity OBSOLETE. Mediates the adhesion of the cell to other cells or to the extracellular matrix. CHEBI:140691 beta-D-Gal-(1->3)-beta-D-GalNAc-(1->3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140691 GO:0044768 NMS complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044768 NMS complex association involved in chromosome segregation|Ndc80-MIND-Spc7 complex formation|KMN network assembly involved in chromosome segregation|KMN complex interaction involved in chromosome segregation|KNL-1-Mis12-Ndc80 formation|KMN kinetochore network assembly|NMS complex assembly involved in kinetochore assembly|KMN kinetochore network formation|KNL-1-Mis12-Ndc80 assembly|NMS complex formation|Ndc80-MIND-Spc7 complex assembly The aggregation, arrangement and bonding together of a set of components to form an NMS complex. The NMS complex results from the association of two subcomplexes (known as MIND and Ndc80 in Schizosaccharomyces) and is required for kinetochore assembly. GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044769 Enables the transfer of ions from one side of a membrane to the other according to the reaction: ATP + H2O + ion(in) = ADP + phosphate + ion(out), by a rotational mechanism. GO:0044766 multi-organism transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044766 The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore, involving more than one organism. GO:0044767 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044767 GO:0030156 benzodiazepine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030156 diazepam binding inhibitor activity|benzodiazepine receptor ligand Interacting selectively and non-covalently with the peripheral benzodiazepine receptor (PBR). GO:0030157 pancreatic juice secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030157 The regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine. Pancreatic juice is slightly alkaline and contains numerous enzymes and inactive enzyme precursors including alpha-amylase, chymotrypsinogen, lipase, procarboxypeptidase, proelastase, prophospholipase A2, ribonuclease, and trypsinogen. Its high concentration of bicarbonate ions helps to neutralize the acid from the stomach. GO:0030154 cell differentiation biolink:BiologicalProcess go-plus goslim_drosophila|goslim_generic|goslim_chembl|goslim_mouse|goslim_agr|goslim_plant http://purl.obolibrary.org/obo/GO_0030154 Wikipedia:Cellular_differentiation The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. CHEBI:150013 emodin anthrone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_150013 GO:0030155 regulation of cell adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030155 cell adhesion receptor regulator activity Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix. GO:0030152 bacteriocin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030152 bacteriocin anabolism|bacteriocin synthesis|bacteriocin formation|bacteriocin biosynthesis The chemical reactions and pathways resulting in the formation of a bacteriocin, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary. GO:0030153 bacteriocin immunity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030153 A process that mediates resistance to a bacteriocin: any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary. GO:0030150 protein import into mitochondrial matrix biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030150 protein transport into mitochondrial matrix|mitochondrial translocation|mitochondrial matrix protein import The import of proteins across the outer and inner mitochondrial membranes into the matrix. Unfolded proteins enter the mitochondrial matrix with a chaperone protein; the information required to target the precursor protein from the cytosol to the mitochondrial matrix is contained within its N-terminal matrix-targeting sequence. Translocation of precursors to the matrix occurs at the rare sites where the outer and inner membranes are close together. GO:0030151 molybdenum ion binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030151 molybdenum binding Interacting selectively and non-covalently with molybdenum (Mo) ions. PR:000018435 interleukin-16 proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000018435 IL16/ClvPrd An interleukin-16 that has been processed by proteolytic cleavage. GO:0030149 sphingolipid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030149 sphingolipid catabolism|sphingolipid breakdown|sphingolipid degradation The chemical reactions and pathways resulting in the breakdown of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). GO:0030147 obsolete natriuresis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030147 Wikipedia:Natriuresis natriuresis OBSOLETE. The process of renal sodium excretion. PR:000018438 interleukin-18 proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000018438 IL18/ClvPrd An interleukin-18 that has been processed by proteolytic cleavage. GO:0030148 sphingolipid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030148 MetaCyc:PWY-5129 sphingolipid biosynthesis|sphingolipid anabolism|sphingolipid synthesis|sphingolipid formation The chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). GO:0044775 DNA polymerase III, beta sliding clamp processivity factor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044775 A subcomplex of the DNA polymerase III holoenzyme which is responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication. The complex is homodimeric in prokaryotes, and homotrimeric in other species. GO:0044776 DNA polymerase III, core complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044776 The DNA polymerase III core complex consists of the alpha,epsilon and theta subunits and is carries out the polymerase and the 3'-5' exonuclease proofreading activities. GO:0044773 mitotic DNA damage checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044773 A mitotic cell cycle checkpoint that detects and negatively regulates progression through the cell cycle in response to DNA damage. GO:0044774 mitotic DNA integrity checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044774 mitotic cell cycle G2/M transition decatenation checkpoint A mitotic cell cycle process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and ends with signal transduction. GO:0044771 meiotic cell cycle phase transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044771 cell cycle transition The cell cycle process by which a cell commits to entering the next meiotic cell cycle phase. GO:0044772 mitotic cell cycle phase transition biolink:BiologicalProcess go-plus goslim_pombe http://purl.obolibrary.org/obo/GO_0044772 The cell cycle process by which a cell commits to entering the next mitotic cell cycle phase. GO:0044770 cell cycle phase transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044770 cell cycle transition The cell cycle process by which a cell commits to entering the next cell cycle phase. GO:0044779 meiotic spindle checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044779 A cell cycle checkpoint that delays the metaphase/anaphase transition of a meiotic nuclear division until the spindle is correctly assembled and that the chromosomes are attached to the spindle. GO:0044777 single-stranded DNA-binding protein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044777 SSB complex A homotetrameric protein complex that is essential for DNA replication. It supercoils the single-stranded DNA preventing DNA duplexing before the polymerase holoenzyme passes and synthesizes the complementary strand. It is also involved in DNA recombination and repair. GO:0044778 meiotic DNA integrity checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044778 A meiotic cell cycle process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and ends with signal transduction. GO:0030145 manganese ion binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030145 manganese binding Interacting selectively and non-covalently with manganese (Mn) ions. GO:0030146 obsolete diuresis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030146 Wikipedia:Diuresis renal water excretion|positive regulation of renal water excretion|diuresis OBSOLETE. The process of renal water excretion. GO:0030143 COPI-coated inter-Golgi transport vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030143 NIF_Subcellular:sao1382918459 inter-Golgi transport constitutive secretory pathway transport vesicle A vesicle that mediates transport of cargo within the Golgi complex (for example, between cisternae of the Golgi stack). GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030144 Reactome:R-HSA-975916|Reactome:R-HSA-9696980|RHEA:16921|MetaCyc:2.4.1.155-RXN|EC:2.4.1.155 GnTV activity|alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-alpha-mannoside beta1->6-acetylglucosaminyltransferase activity|alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase activity|alpha-1,3(6)-mannosylglycoprotein beta-1,6-N-acetylglucosaminyltransferase activity|UDP-N-acetylglucosamine:alpha-mannoside-beta-1,6 N-acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:6-[2-(N-acetyl-beta-D-glucosaminyl)-alpha-D-mannosyl]-glycoprotein 6-beta-N-acetyl-D-glucosaminyltransferase activity|uridine diphosphoacetylglucosamine-alpha-mannoside beta-1->6-acetylglucosaminyltransferase activity|UDP-N-acetylglucosamine:alpha-mannoside-beta1,6 N-acetylglucosaminyltransferase activity|N-acetylglucosaminyltransferase V activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3(6)-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl,1,6(3))-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,2-(N-acetyl-beta-D-glucosaminyl-1,6)-1,2-alpha-D-mannosyl-1,3(6)-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6(3))-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R. Only branched mannose glycopeptides with non-reducing N-acetylglucosamine terminal residues act as acceptors. GO:0030141 secretory granule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030141 secretory vesicle A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules. GO:0030142 COPI-coated Golgi to ER transport vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030142 Golgi-ER transport vesicle|Golgi-endoplasmic reticulum transport vesicle|Golgi to endoplasmic reticulum transport vesicle|Golgi to ER constitutive secretory pathway transport vesicle|retrograde transport vesicle A vesicle that mediates transport from the Golgi to the endoplasmic reticulum. GO:0030140 trans-Golgi network transport vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030140 trans-Golgi network constitutive secretory pathway transport vesicle|TGN transport vesicle A vesicle that mediates transport between the trans-Golgi network and other parts of the cell. CHEBI:23953 erythromycins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23953 CHEBI:47921 cis-2-coumarate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47921 CHEBI:47923 tripeptide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47923 UBERON:0004383 epiphysis of tibia biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004383 tibial epiphysis An epiphysis that is part of a tibia [Automatically generated definition]. UBERON:0004384 epiphysis of femur biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004384 femoral epiphysis An epiphysis that is part of a femur [Automatically generated definition]. UBERON:0004381 skeleton of limb biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004381 set of bones of limb|limb skeleton|free limb skeleton The collection of all skeletal elements in an individual limb. UBERON:0004382 epiphysis of humerus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004382 humeral epiphysis An epiphysis that is part of a humerus [Automatically generated definition]. UBERON:0004380 proximal epiphysis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004380 proximal end of long bone An epiphysis that is on the proximal side of the bone. CHEBI:23957 erythroses biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23957 CHEBI:47925 3-coumaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47925 CHEBI:23958 erythrulose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_23958 CHEBI:23955 erythronolide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23955 CHEBI:47927 3-coumarate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47927 CHEBI:23956 erythrose phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23956 CHEBI:47928 trans-3-coumarate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47928 UBERON:0004389 epiphysis of metatarsal bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004389 epiphysis of metatarsal|metatarsal bone epiphysis|metatarsal epiphysis An epiphysis that is part of a metatarsal bone [Automatically generated definition]. UBERON:0004387 epiphysis of phalanx of manus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004387 epiphysis of phalanx of hand|epiphysis of phalanx of finger An epiphysis that is part of a phalanx of a manus [Automatically generated definition]. UBERON:0004388 epiphysis of fibula biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004388 fibula epiphysis An epiphysis that is part of a fibula [Automatically generated definition]. CHEBI:23965 estradiol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_23965 CHEBI:47910 S-substituted L-cysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47910 CHEBI:47911 S-substituted N-acetyl-L-cysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47911 CHEBI:47912 S-organyl-L-cysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47912 UBERON:0004374 vitelline vasculature biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004374 vitelline system|omphalomesenteric system|vitelline bloos vessel system vascular network that is connected to the yolk sac. UBERON:0004375 bone of free limb or fin biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004375 bone of appendage|appendage bone|bone of free segment of appendicular skeleton A bone that is part of an appendage [Automatically generated definition]. UBERON:0004370 anterior limiting lamina of cornea biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004370 anterior elastic lamina|Bowman's membrane|Reichert's membrane|anterior limiting lamina|Bowman's anterior elastic lamina|lamina limitans anterior corneae|Bowman's layer|lamina limitans anterior (cornea)|anterior limiting lamina of cornea|anterior limiting membrane A transparent homogeneous acellular layer, 6 to 9 um thick, lying between the basal lamina of the outer layer of stratified epithelium and the substantia propria of the cornea; it is considered to be a basement membrane. CHEBI:47913 S-hydrocarbyl-L-cysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47913 CHEBI:47914 S-prenyl-L-cysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47914 CHEBI:23966 estrane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_23966 CHEBI:47915 S-alkyl-L-cysteine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47915 CHEBI:47916 flavonoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47916 UBERON:0004378 proximal metaphysis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004378 proximal diaphyseal end of long bone A metaphysis that is in the proximal side of a diaphysis. CHEBI:47917 1-ribosylbenzimidazole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47917 UBERON:0004379 distal epiphysis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004379 distal end of long bone An epiphysis that is on the distal side of the bone. UBERON:0004376 fin bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004376 bone of fin A bone that is part of a fin [Automatically generated definition]. UBERON:0004377 distal metaphysis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004377 distal diaphyseal end of long bone A metaphysis that is in the distal side of a diaphysis. CHEBI:23931 epoxy monocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23931 CHEBI:72900 cardiolipin 72:8(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72900 CHEBI:47901 alkanesulfonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47901 UBERON:0004363 pharyngeal arch artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004363 branchial aortic arches|branchial arch artery|a. arcuum pharyngeorum|embryonic aortic arch artery|pharyngeal arch artery|aortic arches|aortic arch artery|pharyngeal arch artery|arteriae arcuum pharyngeorum|pharyngeal arch arteries|PAA|aortic arch|branchial aortic arches One of a series of paired embryological vascular structures formed within a pharyngeal arch; in the adult, some of these vessels give rise to the great vessels[MP] UBERON:0004364 ectoplacental cone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004364 placenta - ectoplacental cone|epamniotic cone thickened trophoblast of the blastocyst in rodents that becomes the fetal portion of the placenta UBERON:0004362 pharyngeal arch 1 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004362 1st visceral arch|1st pharyngeal arch|first pharyngeal arch|1st arch|branchial arch 1|arcus pharyngeus primus|first branchial arch|visceral arch 1|first visceral arch|mandibular arch The first of the series of pharyngeal arches that develop into jaw bones or their homologs, and their associated nerves and arteries CHEBI:47902 idopyranuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47902 CHEBI:47903 L-idopyranuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47903 CHEBI:47904 4-maleylacetoacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47904 CHEBI:47905 coniferyl acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47905 UBERON:0004367 Descemet's membrane biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004367 Descemet membrane|posterior limiting membrane|posterior limiting lamina of cornea|lamina limitans posterior corneae|lamina limitans posterior|Descemet's posterior elastic lamina|posterior limiting lamina A transparent homogeneous acellular layer found between the substantia propria and the endothelial layer of the cornea[MP]. CHEBI:47907 3-oxo-Delta(5)-steroid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47907 UBERON:0004365 vitelline blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004365 blood vessel that is connected to the yolk sac. CHEBI:47908 alkanethiol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47908 CHEBI:47909 3-oxo-Delta(4) steroid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47909 CHEBI:23943 ergot alkaloid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23943 UBERON:0004356 apical ectodermal ridge biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004356 crista ectodermalis apicalis|AER|apical epidermal ridge multilayered ectodermal region at the distal tip of a limb or fin bud necessary for the proper development of the underlying mesenchyme[MP,modified]. Along with the zone of polarizing activity, it is a crucial organizing region during limb development[WP]. UBERON:0004357 paired limb/fin bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004357 limb - fin bud|paired appendage bud|paired limb/fin bud An outgrowth on the lateral trunk of the embryo that develops into a limb or paired fin. The limb/fin bud is divided into ectoderm and mesenchyme[cjm, modified from MP]. CHEBI:23948 erythro-3-methylmalic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23948 CHEBI:5924 EC 3.4.21.* (serine endopeptidase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_5924 CHEBI:23924 enzyme inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23924 CHEBI:23925 (+)-5-epi-aristolochene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_23925 CHEBI:23929 episterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_23929 CHEBI:72944 3''-deamino-3''-hydroxykanamycin B(4+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72944 CHEBI:72945 3''-deamino-3''-hydroxykanamycin C(3+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72945 CHEBI:72946 3''-deamino-3''-hydroxykanamycin X(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72946 CHEBI:72947 kanamycin D(3+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72947 CHEBI:72948 deoxybrevianamide E biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72948 CHEBI:72949 chanoclavine-I(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72949 CHEBI:72950 (7,8-dihydropterin-6-yl)methyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72950 CHEBI:72951 N-[(7,8-dihydropterin-6-yl)methyl]-4-(beta-D-ribofuranosyl)aniline 5'-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72951 CHEBI:72952 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72952 CHEBI:72956 N-dodecanoylsphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72956 CHEBI:72957 N-tetradecanoylsphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72957 CHEBI:72959 N-hexadecanoylsphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72959 UBERON:0004390 epiphysis of metacarpal bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004390 metacarpal bone epiphysis|epiphysis of metacarpal|metacarpal epiphysis An epiphysis that is part of a metacarpal bone [Automatically generated definition]. CHEBI:23902 icosenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23902 CHEBI:23906 monoatomic cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23906 CHEBI:23905 monoatomic anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23905 CHEBI:57329 2,4-dichlorobenzoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57329 GO:0019739 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019739 CHEBI:33352 manganese group element atom biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33352 CHEBI:57320 citramalyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57320 GO:0019737 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019737 CHEBI:140714 alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140714 GO:0019738 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019738 GO:0019735 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019735 CHEBI:33356 iron group element atom biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33356 GO:0019736 peptidyl-sarcosine incorporation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019736 RESID:AA0063 The incorporation of sarcosine (N-methylglycine) into non-coded peptides. GO:0019733 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019733 CHEBI:33358 cobalt group element atom biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33358 PATO:0002266 3-D shape biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PATO_0002266 A shape that inheres in a 3 dimensional entity. GO:0019734 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019734 GO:0019731 antibacterial humoral response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019731 An immune response against bacteria mediated through a body fluid. Examples of this process are the antibacterial humoral responses in Mus musculus and Drosophila melanogaster. CHEBI:57327 (S)-methylmalonyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57327 GO:0019732 antifungal humoral response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019732 An immune response against a fungus mediated through a body fluid. An example of this process is the antifungal humoral response in Drosophila melanogaster. CHEBI:57328 3'-dephospho-CoA(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57328 CHEBI:57325 (E,E)-piperonyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57325 GO:0019730 antimicrobial humoral response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019730 An immune response against microbes mediated through a body fluid. Examples of this process are seen in the antimicrobial humoral response of Drosophila melanogaster and Mus musculus. CHEBI:57326 (R)-methylmalonyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57326 UBERON:0004301 middle phalanx biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004301 phalanx II|penultimate phalanx|medial phalanx|intermediate phalanx|phalanx 2 A phalanx located between proximal and distal phalanges. CHEBI:57323 cis-tetradec-11-enoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57323 UBERON:0004302 proximal phalanx biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004302 phalanx I|proximal-most phalanx|phalanx 1 Proximal-most phalanx within a digit. CHEBI:57324 cinnamoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57324 CHEBI:57321 (3S)-citryl-CoA(6-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57321 CHEBI:33350 chromium group element atom biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33350 UBERON:0004300 distal phalanx biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004300 phalanx distalis|phalanx distalis|terminal phalanx|ungual phalanx Distal-most phalanx within a digit. CHEBI:57322 trans-tetradec-11-enoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57322 GO:0005109 frizzled binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0005109 frizzled-2 binding|fz binding|fz2 ligand|fz2 binding|frizzled ligand|frizzled-2 ligand|fz ligand Interacting selectively and non-covalently with a frizzled (fz) receptor. CHEBI:47993 N,N-dihydroxy-L-tryptophan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47993 CHEBI:47994 L-tryptophan derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47994 GO:0005107 obsolete GPI-linked ephrin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005107 GPI-linked ephrin OBSOLETE. (Was not defined before being made obsolete). CHEBI:47995 hydroxy-L-tryptophan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47995 GO:0005108 obsolete transmembrane ephrin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005108 transmembrane ephrin OBSOLETE. (Was not defined before being made obsolete). CHEBI:47996 dihydroxy-L-tryptophan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47996 CHEBI:47997 D-tryptophan derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47997 GO:0005105 type 1 fibroblast growth factor receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005105 breathless ligand|type 1 fibroblast growth factor receptor ligand|FGFR1 ligand|breathless binding|FGFR1 binding Interacting selectively and non-covalently with the type 1 fibroblast growth factor receptor (FGFR1). GO:0005106 obsolete ephrin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005106 ephrin OBSOLETE. A class of proteins that interact with the ephrin receptors. CHEBI:57318 (S)-3-hydroxyacyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57318 GO:0005103 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005103 GO:0005104 fibroblast growth factor receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005104 FGF receptor binding|fibroblast growth factor receptor ligand|fibroblast growth factor|FGFR binding|FGFR ligand Interacting selectively and non-covalently with the fibroblast growth factor receptor (FGFR). CHEBI:57319 (R)-3-hydroxyacyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57319 GO:0005101 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005101 GO:0005102 signaling receptor binding biolink:MolecularActivity go-plus goslim_flybase_ribbon|goslim_chembl|goslim_mouse|goslim_agr|goslim_plant http://purl.obolibrary.org/obo/GO_0005102 Wikipedia:Ligand_(biochemistry) receptor ligand|receptor binding|receptor-associated protein activity Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. GO:0005100 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005100 CHEBI:47990 N-hydroxy-L-phenylalanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47990 CHEBI:47991 N,N-dihydroxy-L-phenylalanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47991 CHEBI:47992 N-hydroxy-L-tryptophan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47992 CHEBI:5975 iron chelate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_5975 CHEBI:33364 platinum biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33364 GO:0019748 secondary metabolic process biolink:BiologicalProcess go-plus goslim_pir|goslim_plant|goslim_aspergillus|goslim_generic|goslim_pombe|goslim_chembl http://purl.obolibrary.org/obo/GO_0019748 Wikipedia:Secondary_metabolism secondary metabolite metabolism|secondary metabolism|secondary metabolite metabolic process The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients. CHEBI:33365 platinum group metal atom biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33365 CHEBI:33366 copper group element atom biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33366 GO:0019749 cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019749 The directed movement of substances along cytoskeletal elements, such as microfilaments or microtubules, from a nurse cell to an oocyte. GO:0019746 hopanoid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019746 hopanoid anabolism|hopanoid synthesis|hopanoid formation|hopanoid biosynthesis The chemical reactions and pathways resulting in the formation of hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus. GO:0019747 regulation of isoprenoid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019747 regulation of isoprenoid metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving isoprenoids. GO:0019744 hopanoid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019744 hopanoid metabolism The chemical reactions and pathways involving hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus. GO:0019745 pentacyclic triterpenoid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019745 pentacyclic triterpenoid biosynthesis|pentacyclic triterpenoid anabolism|pentacyclic triterpenoid synthesis|pentacyclic triterpenoid formation The chemical reactions and pathways resulting in the formation of pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings. CHEBI:57316 (S)-3-hydroxybutanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57316 GO:0019742 pentacyclic triterpenoid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019742 pentacyclic triterpenoid metabolism The chemical reactions and pathways involving pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings. CHEBI:57317 (3S)-3-carboxy-3-hydroxypropanoyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57317 GO:0019743 hopanoid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019743 hopanoid catabolism|hopanoid degradation|hopanoid breakdown The chemical reactions and pathways resulting in the breakdown of hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus. CHEBI:57314 (2S)-2-methylacyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57314 GO:0019740 nitrogen utilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019740 A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary nitrogen source, usually ammonia, and then activates genes to scavenge the last traces of the primary nitrogen source and to transport and metabolize alternative nitrogen sources. The utilization process begins when the cell or organism detects nitrogen levels, includes the activation of genes whose products detect, transport or metabolize nitrogen-containing substances, and ends when nitrogen is incorporated into the cell or organism's metabolism. GO:0019741 pentacyclic triterpenoid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019741 pentacyclic triterpenoid breakdown|pentacyclic triterpenoid catabolism|pentacyclic triterpenoid degradation The chemical reactions and pathways resulting in the breakdown of pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings. CHEBI:57315 (R)-3-hydroxybutanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57315 CHEBI:57312 (2S,3S)-3-hydroxy-2-methylbutanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57312 CHEBI:57313 (2R)-2-methylacyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57313 CHEBI:57310 presqualene diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57310 CHEBI:57311 (1-hydroxycyclohexyl)acetyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57311 CHEBI:33362 nickel group element atom biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33362 CHEBI:47982 pantetheine 4'-phosphate group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47982 CHEBI:47985 enol ether biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47985 CHEBI:57309 coproporphyrinogen III(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57309 CHEBI:47987 2-amino-2-deoxy-D-glucopyranose 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47987 CHEBI:57307 protoporphyrinogen(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57307 CHEBI:57308 uroporphyrinogen III(8-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57308 CHEBI:47989 enamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47989 CHEBI:33338 aryl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33338 CHEBI:47980 threo-3-methyl-L-aspartic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47980 GO:0019719 obsolete smooth microsome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019719 smooth microsome OBSOLETE. Vesicular particles formed from disrupted endoplasmic reticulum and plasma membranes without any adhering ribosomes. GO:0019717 obsolete synaptosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019717 Wikipedia:Synaptosome synaptosome OBSOLETE. Any of the discrete particles (nerve-ending particles) formed from the clublike presynaptic nerve endings that resist disruption and are snapped or torn off their attachments when brain tissue is homogenized in media isosmotic to plasma. GO:0019718 obsolete rough microsome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019718 rough microsome OBSOLETE. Vesicular particles formed from disrupted endoplasmic reticulum membranes and studded with ribosomes on the outside. GO:0019715 peptidyl-aspartic acid hydroxylation to form L-erythro-beta-hydroxyaspartic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019715 RESID:AA0027 The hydroxylation of peptidyl-aspartic acid to form peptidyl-L-erythro-beta-hydroxyaspartic acid; catalyzed by peptide-aspartate beta-dioxygenase (EC:1.14.11.16). GO:0019716 N-terminal peptidyl-alanine monomethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019716 RESID:AA0061 The monomethylation of the N-terminal alanine of proteins to form the derivative peptidyl-N-methyl-L-alanine. GO:0019713 peptidyl-L-glutamic acid 5-methyl ester biosynthetic process from glutamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019713 RESID:AA0072 peptidyl-L-glutamic acid 5-methyl ester formation from glutamine|peptidyl-L-glutamic acid 5-methyl ester synthesis from glutamine|peptidyl-L-glutamic acid 5-methyl ester anabolism from glutamine The coupled methyl esterification and deamidation of peptidyl-glutamine. GO:0019714 peptidyl-glutamine esterification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019714 The addition of an ester group to a glutamine residue in a protein. GO:0019711 peptidyl-beta-carboxyaspartic acid biosynthetic process from peptidyl-aspartic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019711 peptidyl-beta-carboxyaspartic acid anabolism from peptidyl-aspartic acid|peptidyl-beta-carboxyaspartic acid synthesis from peptidyl-aspartic acid|peptidyl-beta-carboxyaspartic acid formation from peptidyl-aspartic acid The chemical reactions and pathways resulting in the formation of peptidyl-beta-carboxyaspartic acid from other compounds, including peptidyl-aspartic acid. GO:0019712 peptidyl-L-glutamic acid 5-methyl ester biosynthetic process from glutamic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019712 RESID:AA0072 peptidyl-L-glutamic acid 5-methyl ester formation from glutamic acid|peptidyl-L-glutamic acid 5-methyl ester synthesis from glutamic acid|peptidyl-L-glutamic acid 5-methyl ester anabolism from glutamic acid The methyl esterification of peptidyl-glutamic acid. CHEBI:57305 glycine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57305 GO:0019710 peptidyl-asparagine methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019710 RESID:AA0070|RESID:AA0311 The methylation of peptidyl-asparagine to form peptidyl-N4-methyl-L-asparagine or peptidyl-N4,N4-dimethyl-L-asparagine. CHEBI:57306 protoporphyrin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57306 CHEBI:57303 deoxyamidinoproclavaminic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57303 CHEBI:57304 N(2)-(2-carboxyethyl)-L-arginine dizwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57304 CHEBI:57301 dihydroclavaminic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57301 CHEBI:57302 proclavaminic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57302 CHEBI:57300 clavaminic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57300 CHEBI:47977 2-amino-2-deoxy-D-glucopyranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47977 CHEBI:47978 N-acetylmuramate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47978 GO:0019728 peptidyl-allysine oxidation to 2-aminoadipic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019728 RESID:AA0370 The oxidation of allysine to 2-aminoadipic acid. GO:0019729 peptide cross-linking via 2-imino-glutaminyl-5-imidazolinone glycine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019729 RESID:AA0189 biosynthetic process of protein-protein cross-link via 2-imino-glutaminyl-5-imidazolinone glycine|biosynthesis of protein-protein cross-link via 2-imino-glutaminyl-5-imidazolinone glycine The formation of the fluorescent protein FP583 chromophore cross-link from the alpha-carboxyl carbon of residue n, a glutamine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons. GO:0019726 mevaldate reductase (NADPH) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019726 KEGG_REACTION:R02247|MetaCyc:MEVALDATE-REDUCTASE-NADPH-RXN|RHEA:20193|EC:1.1.1.33 mevaldate (reduced nicotinamide adenine dinucleotide phosphate) reductase|(R)-mevalonate:NADP+ oxidoreductase Catalysis of the reaction: (R)-mevalonate + NADP(+) = H(+) + mevaldate + NADPH. GO:0019727 mevaldate reductase (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019727 KEGG_REACTION:R02246|RHEA:13221|EC:1.1.1.32|MetaCyc:MEVALDATE-REDUCTASE-RXN Catalysis of the reaction: (R)-mevalonate + NAD(+) = H(+) + mevaldate + NADH. GO:0019724 B cell mediated immunity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019724 B-cell mediated immunity|B-lymphocyte mediated immunity|B-lymphocyte mediated immune effector process|B-cell mediated immune effector process|B lymphocyte mediated immunity|B lymphocyte mediated immune effector process Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells. GO:0019725 cellular homeostasis biolink:BiologicalProcess go-plus goslim_candida|goslim_plant|goslim_aspergillus http://purl.obolibrary.org/obo/GO_0019725 Any process involved in the maintenance of an internal steady state at the level of the cell. GO:0019722 calcium-mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019722 Wikipedia:Calcium_signaling calcium ion signaling|calcium-mediated signalling|calcium signaling|calcium signalling Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions. CHEBI:33347 vanadium group element atom biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33347 GO:0019723 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019723 GO:0019720 Mo-molybdopterin cofactor metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019720 Moco metabolic process|Mo-molybdopterin cofactor metabolism|Moco metabolism The chemical reactions and pathways involving the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands. CHEBI:47979 N-acetyl-alpha-muramate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47979 GO:0019721 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019721 CHEBI:33340 zinc group element atom biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33340 CHEBI:47960 (2E,4Z)-5-hydroxypenta-2,4-diene-1,2,5-tricarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47960 CHEBI:47961 (2E,4Z)-5-hydroxypenta-2,4-diene-1,2,5-tricarboxylate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47961 CHEBI:47962 aldehydo-D-galacturonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47962 CHEBI:47964 aurone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47964 CHEBI:23997 ethyl 3-hydroxyhexanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_23997 CHEBI:47965 N-acetylmuramic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47965 CHEBI:47967 N-acetyl-beta-muramic acid 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47967 CHEBI:33317 boron group element atom biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33317 CHEBI:33318 main group element atom biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33318 PATO:0002226 subcylindrical biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PATO_0002226 A cylindrical shape quality inhering in a bearer by virtue of the bearer's being imperfectly cylindrical or approximately cylindrical. CHEBI:23990 ethyl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_23990 UBERON:0004341 primitive streak biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004341 primitive streak - blastopore - germ ring The primitive streak is a structure that forms during the early stages of avian, reptilian and mammalian embryonic development[WP]. the midline ridge of the embryonic epiblast that later develops into mesoderm and endoderm[MP] UBERON:0004340 allantois biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004340 allantoic bud A membranous sac that develops from the posterior part of the alimentary canal in the embryos of mammals, birds, and reptiles, and it is important in the formation of the umbilical cord and placenta in mammals[VHOG]. CHEBI:47968 N-acetylmuramic acid 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47968 UBERON:0004347 limb bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004347 limbbud|gemmae membrorum|limb buds An outgrowth on the lateral trunk of the embryo that develops into a limb. The limb bud is divided into ectoderm and mesenchyme[cjm, modified from MP]. UBERON:0004348 optic eminence biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004348 The embryonic structure that gives rise to the corneal ectoderm UBERON:0004345 trophectoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004345 outermost layer of cells in the blastodermic vesicle, which will develop into the trophoblast layer and then contact the endometrium and take part in establishing the embryo's means of nutrition CHEBI:47950 keto-D-fructuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47950 CHEBI:47951 primary fluorescent chlorophyll catabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47951 CHEBI:47952 D-glucopyranuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47952 CHEBI:47954 beta-D-galacturonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47954 CHEBI:47955 (2R)-phycocyanobilin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47955 CHEBI:47956 thiocarboxamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47956 CHEBI:33327 silicon oxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33327 CHEBI:33328 silicon oxoacid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33328 GO:0019708 peptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019708 RESID:AA0309 peptidyl-glycine cholesteryl ester formation from peptidyl-glycine|peptidyl-glycine cholesteryl ester anabolism from peptidyl-glycine|peptidyl-glycine cholesteryl ester synthesis from peptidyl-glycine The synthesis of peptidyl-glycine cholest-5-en-3-beta-ol ester at the carboxy-terminus of autolytically cleaved proteins. GO:0019709 iron incorporation into iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019709 RESID:AA0310 iron incorporation into iron-sulphur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulphide The incorporation of iron into a nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide, found in carbon monoxide dehydrogenase. GO:0019706 protein-cysteine S-palmitoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019706 RHEA:36683|EC:2.3.1.225|Reactome:R-HSA-5682084|Reactome:R-HSA-9647982|Reactome:R-HSA-9021072 protein-cysteine S-palmitoleyltransferase activity Catalysis of the transfer of a palmitoyl (systematic name, hexadecanoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein]. GO:0019707 protein-cysteine S-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019707 RHEA:63372 Catalysis of the transfer of an acyl group to a sulfur atom on the cysteine of a protein molecule. GO:0019704 peptidyl-L-cysteine S-myristoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019704 RESID:AA0307 peptidyl-S-myristoyl-L-cysteine formation from peptidyl-cysteine|peptidyl-S-myristoyl-L-cysteine synthesis from peptidyl-cysteine|peptidyl-S-myristoyl-L-cysteine anabolism from peptidyl-cysteine|peptidyl-S-myristoyl-L-cysteine biosynthetic process from peptidyl-cysteine The modification of peptidyl-cysteine to form peptidyl-S-myristoyl-L-cysteine. GO:0019705 protein-cysteine S-myristoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019705 RHEA:59736 Catalysis of the transfer of a myristoyl (systematic name, tetradecanoyl) group to a sulfur atom on a cysteine residue of a protein molecule in the reaction: tetradecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-tetradecanoyl-L-cysteinyl-[protein]. GO:0019702 protein-arginine N5-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019702 RHEA:48116|EC:2.1.1.322 protein-arginine delta-N-methyltransferase activity|S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-N5-methyl-L-arginine-forming)|type IV PRMT activity|type IV protein arginine methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the delta-nitrogen atom of peptidyl-arginine residues. The reaction is S-adenosyl-L-methionine + [protein]-L-arginine = S-adenosyl-L-homocysteine + [protein]-N5-methyl-L-arginine. GO:0019703 coenzyme A-peptidyl-cysteine covalent linking biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019703 RESID:AA0306 The covalent linkage of coenzyme A and peptidyl-cysteine to form L-cysteine coenzyme A disulfide. GO:0019700 organic phosphonate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019700 phosphonate catabolism|phosphonate degradation|phosphonate breakdown|organophosphonate catabolic process The chemical reactions and pathways resulting in the breakdown of phosphonates, any organic compound containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Catabolism of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included. GO:0019701 peptidyl-arginine N5-methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019701 RESID:AA0305 peptidyl-arginine delta-N-methylation The methylation of peptidyl-arginine on the internal nitrogen-5 (N5) atom (also called delta-nitrogen) to form peptidyl-N5-methyl-L-arginine. CHEBI:47957 (3E)-phycocyanobilin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47957 UBERON:0004339 vault of skull biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004339 skull roof|calva|skullcap|skull vault|calvaria|cranial vault|calvarium Upper part of skull, consisting of parietals, frontals, post-parietals, and in some species the squamosal and a portion of the alisphenoid CHEBI:47958 nicotinic acetylcholine receptor agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47958 CHEBI:47959 5-hydroxypenta-2,4-diene-1,2,5-tricarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47959 CHEBI:47940 4,6-dioxohept-2-enedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47940 CHEBI:47941 4,6-dioxohept-2-enedioate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47941 CHEBI:47942 pantetheine 4'-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47942 CHEBI:23976 ethanediol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23976 CHEBI:47947 keto-D-tagatose 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47947 CHEBI:23982 ethanols biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23982 RO:0002180 has component biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002180 RO:0002180 w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type. CHEBI:23981 ethanolamines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23981 CHEBI:47931 beta-D-glucosyl-(1->4)-D-mannopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47931 CHEBI:47932 D-glucosyl-(1->4)-D-mannose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47932 CHEBI:47933 D-glucopyranosyl-(1->4)-D-mannopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47933 CHEBI:33305 tellurium molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33305 CHEBI:33306 carbon group element atom biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33306 CHEBI:33307 thiocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33307 CHEBI:33308 carboxylic ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33308 CHEBI:33300 pnictogen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33300 CHEBI:33301 bismuth atom biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33301 CHEBI:33302 pnictogen molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33302 CHEBI:33303 chalcogen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33303 CHEBI:33304 chalcogen molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33304 GO:0030259 lipid glycosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030259 Covalent attachment of a glycosyl residue to a lipid molecule. GO:0030257 type III protein secretion system complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030257 TTSS complex|T3SS complex A complex of approximately 20 proteins, most of which are located in the cytoplasmic membrane that carries out protein secretion in the bacterial type III secretion system; type III secretion also requires a cytoplasmic, probably membrane-associated ATPase. GO:0030258 lipid modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030258 The covalent alteration of one or more fatty acids in a lipid, resulting in a change in the properties of the lipid. RO:0002297 results in formation of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002297 RO:0002297 GO:0005299 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005299 RO:0002298 results in morphogenesis of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002298 RO:0002298 The relationship that links an entity with the process that results in the formation and shaping of that entity over time from an immature to a mature state. RO:0002299 results in maturation of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002299 RO:0002299 The relationship that links an entity with a process that results in the progression of the entity over time that is independent of changes in it's shape and results in an end point state of that entity. GO:0005297 proline:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005297 hydrogen/proline transporter Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: proline(out) + H+(out) = proline(in) + H+(in). GO:0005298 proline:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005298 RHEA:28967|Reactome:R-HSA-444100 sodium/proline symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: proline(out) + Na+(out) = proline(in) + Na+(in). GO:0005295 neutral amino acid:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005295 neutral amino acid-sodium cotransporter|sodium/neutral amino acid transporter Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neutral amino acid(out) + Na+(out) = neutral amino acid(in) + Na+(in). FAO:0001001 hypha biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/FAO_0001001 A long, branching filamentous structure formed by a vegetatively growing fungus. GO:0005296 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005296 RO:0002295 results in developmental progression of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002295 RO:0002295 p results in the developmental progression of s iff p is a developmental process and s is an anatomical structure and p causes s to undergo a change in state at some point along its natural developmental cycle (this cycle starts with its formation, through the mature structure, and ends with its loss). GO:0005293 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005293 RO:0002296 results in development of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002296 RO:0002296 p 'results in development of' c if and only if p is a developmental process and p results in the state of c changing from its initial state as a primordium or anlage through its mature state and to its final state. GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005294 neutral L-amino acid porter activity Enables the transfer of a neutral L-amino acid from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. GO:0030255 protein secretion by the type IV secretion system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030255 protein secretion by the type IV protein secretion system|protein secretion by the T4SS|type IV protein secretion system The process in which proteins are transferred into the extracellular milieu or directly into host cells, via the type IV protein secretion system. GO:0030256 type I protein secretion system complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030256 ABC translocator complex A complex of three secretory proteins that carry out secretion in the type I secretion system: an inner membrane transport ATPase (termed ABC protein for ATP-binding cassette), which provides the energy for protein secretion; an outer membrane protein, which is exported via the sec pathway; and a membrane fusion protein, which is anchored in the inner membrane and spans the periplasmic space. GO:0030253 protein secretion by the type I secretion system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030253 type I protein secretion system|protein secretion by the TOSS|protein secretion by the type I protein secretion system The process in which proteins are secreted into the extracellular milieu via the type I secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins. GO:0030254 protein secretion by the type III secretion system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030254 protein secretion by the TTSS|protein secretion by the T3SS|type III protein secretion system|protein secretion by the T3S|protein secretion by the type III protein secretion system The process in which proteins are transferred into the extracellular milieu or directly into host cells by the bacterial type III secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins. GO:0030251 guanylate cyclase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030251 Stops, prevents or reduces the activity of guanylate cyclase. GO:0030252 growth hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030252 somatotropin secretion The regulated release of growth hormone from secretory granules into the blood. GO:0030250 guanylate cyclase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030250 guanylin Binds to and increases the activity of guanylate cyclase. GO:0030248 cellulose binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030248 Interacting selectively and non-covalently with cellulose. GO:0030249 guanylate cyclase regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030249 Modulates the activity of guanylate cyclase. GO:0030246 carbohydrate binding biolink:MolecularActivity go-plus goslim_agr|goslim_pir|goslim_plant|goslim_drosophila|goslim_metagenomics|goslim_flybase_ribbon|goslim_chembl http://purl.obolibrary.org/obo/GO_0030246 selectin|sugar binding Interacting selectively and non-covalently with any carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates. GO:0030247 polysaccharide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030247 polysaccharide assembly with MHC class II protein complex Interacting selectively and non-covalently with any polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. RO:0002286 developmentally succeeded by biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002286 RO:0002286 Inverse of developmentally preceded by RO:0002285 developmentally_replaces biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002285 RO:0002285 GO:0030244 cellulose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030244 MetaCyc:PWY-1001 cellulose biosynthesis|cellulose anabolism|cellulose synthesis|cellulose formation The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation. GO:0030245 cellulose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030245 cellulose degradation|cellulose breakdown|cellulose catabolism The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation. GO:0030242 autophagy of peroxisome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030242 pexophagy|peroxisome degradation The process in which peroxisomes are delivered to a type of vacuole and degraded in response to changing nutrient conditions. GO:0030243 cellulose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030243 cellulose metabolism The chemical reactions and pathways involving cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation. GO:0030240 skeletal muscle thin filament assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030240 The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in skeletal muscle. OBO:cl#lacks_part lacks_part biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/cl#lacks_part lacks_part GO:0030241 skeletal muscle myosin thick filament assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030241 The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in skeletal muscle. GO:0030239 myofibril assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030239 Formation of myofibrils, the repeating units of striated muscle. GO:0030237 female sex determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030237 The specification of female sex of an individual organism. GO:0030238 male sex determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030238 The specification of male sex of an individual organism. GO:0030235 nitric-oxide synthase regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030235 nitric oxide synthase regulator activity Modulates the activity of nitric oxide synthase. GO:0005279 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005279 GO:0030236 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030236 GO:0005277 acetylcholine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005277 Reactome:R-HSA-264615 Enables the transfer of acetylcholine from one side of a membrane to the other. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions. GO:0005278 acetylcholine:proton antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005278 acetylcholine:hydrogen antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + acetylcholine(in) = H+(in) + acetylcholine(out). GO:0005275 amine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005275 amine/polyamine transmembrane transporter activity|amino acid-polyamine transmembrane transporter activity|amine/amide/polyamine channel activity Enables the transfer of amines, including polyamines, from one side of a membrane to the other. Amines are organic compounds that are weakly basic in character and contain an amino (-NH2) or substituted amino group. GO:0005276 obsolete vesicular amino acid:proton antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005276 hydrogen:vesicular amine antiporter activity|vesicular hydrogen:amino acid antiporter activity OBSOLETE. Enables the transfer of a solute or solutes from one side of a vesicle membrane to the other according to the reaction: H+(in) + amino acid(out) = H+(out) + amino acid(in). GO:0005274 allantoin:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005274 allantoin uptake transmembrane transporter activity|allantoin permease activity|allantoin/allantoate transporter Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: allantoin(out) + H+(out) = allantoin(in) + H+(in) by secondary active transport. GO:0005272 sodium channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005272 Reactome:R-HSA-3295580|Reactome:R-HSA-2730664 Enables the facilitated diffusion of a sodium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. GO:0005280 amino acid:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005280 Reactome:R-HSA-8875623 cation/amino acid symporter|hydrogen:amino acid symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + H+(out) = amino acid(in) + H+(in). GO:0005281 obsolete general amino acid permease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005281 general amino acid permease activity|general amino acid transporter OBSOLETE. (Was not defined before being made obsolete). CHEBI:149591 (dihydroxyphenyl)propanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_149591 GO:0030233 deoxynucleotide transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030233 Catalyzes transport of all four deoxy (d) NDPs, and, less efficiently, the corresponding dNTPs, in exchange for dNDPs, ADP, or ATP. GO:0030234 enzyme regulator activity biolink:MolecularActivity go-plus goslim_generic|goslim_chembl|goslim_mouse|goslim_agr|goslim_candida|goslim_yeast|goslim_pir|goslim_plant|goslim_drosophila|goslim_aspergillus http://purl.obolibrary.org/obo/GO_0030234 enzyme modulator|catalytic regulator activity|metalloenzyme regulator activity Binds to and modulates the activity of an enzyme. GO:0030231 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030231 GO:0030232 insulin control element activator complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030232 ICE activator complex Transcription factor complex that binds to the insulin control element (ICE), a DNA sequence element found within the 5'-flanking region of the insulin gene, and activates ICE-mediated transcription. GO:0030230 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030230 GO:0030228 lipoprotein particle receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030228 lipoprotein receptor activity|plasma lipoprotein particle receptor activity Combining with a lipoprotein particle and delivering the lipoprotein particle into the cell via endocytosis. A lipoprotein particle, also known as a lipoprotein, is a clathrate complex consisting of a lipid enwrapped in a protein host without covalent binding in such a way that the complex has a hydrophilic outer surface consisting of all the protein and the polar ends of any phospholipids. GO:0030229 very-low-density lipoprotein particle receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030229 Wikipedia:VLDL_receptor apolipoprotein E receptor activity|very-low-density lipoprotein receptor activity|VLDL receptor Combining with a very-low-density lipoprotein particle and delivering the very-low-density lipoprotein into the cell via endocytosis. GO:0030226 apolipoprotein receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030226 Combining with an apolipoprotein to initiate a change in cell activity. GO:0030227 obsolete apolipoprotein E receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030227 apolipoprotein E receptor activity|ApoE receptor OBSOLETE. Combining with apolipoprotein E to initiate a change in cell activity. GO:0030224 monocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030224 monocyte cell differentiation The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a monocyte. GO:0030225 macrophage differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030225 macrophage cell differentiation The process in which a relatively unspecialized monocyte acquires the specialized features of a macrophage. RO:0002264 acts upstream of or within biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002264 RO:0002264 affects c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process. GO:0005288 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005288 GO:0005289 high-affinity arginine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005289 high affinity arginine transmembrane transporter activity|high-affinity arginine transporter activity Enables the transfer of arginine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. GO:0005286 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005286 GO:0005287 high-affinity basic amino acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005287 high affinity basic amino acid transmembrane transporter activity|high-affinity basic amino acid transporter activity Enables the transfer of basic amino acids from one side of a membrane to the other. Acidic amino acids have a pH above 7. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. GO:0005284 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005284 GO:0005285 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005285 GO:0005282 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005282 RO:0002263 acts upstream of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002263 RO:0002263 c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes. GO:0005283 amino acid:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005283 insulin-activated sodium/amino acid transporter activity|sodium:amino acid symporter activity|sodium/excitatory amino acid cotransporter activity|sodium/amino acid transporter activity|sodium/excitatory amino acid symporter activity|insulin-activated sodium:amino acid symporter activity|insulin-activated sodium:amino acid transporter activity|sodium:amino acid transporter activity|glutamate/aspartate:sodium symporter activity|isoleucine/valine:sodium symporter activity|threonine/serine:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + Na+(out) = amino acid(in) + Na+(in). GO:0005291 high-affinity L-histidine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005291 high affinity L-histidine transmembrane transporter activity|high affinity histidine permease activity Enables the transfer of L-histidine from one side of a membrane to the other. L-histidine is 2-amino-3-(1H-imidazol-4-yl)propanoic acid. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. GO:0005292 high-affinity lysine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005292 high affinity lysine transmembrane transporter activity|high affinity lysine transporter activity Enables the transfer of lysine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. GO:0005290 L-histidine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005290 L-histidine transporter activity|histidine/arginine/lysine/ornithine porter activity Enables the transfer of L-histidine from one side of a membrane to the other. L-histidine is 2-amino-3-(1H-imidazol-4-yl)propanoic acid. RO:0002258 developmentally_preceded_by biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002258 RO:0002258 Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p GO:0030222 eosinophil differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030222 eosinophil cell development|eosinophil cell differentiation|eosinophil development The process in which a relatively unspecialized myeloid precursor cell acquires the specializes features of an eosinophil. GO:0030223 neutrophil differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030223 neutrophil granulocyte differentiation|neutrophil cell differentiation|neutrophil granulocytopoiesis The process in which a myeloid precursor cell acquires the specialized features of a neutrophil. GO:0030220 platelet formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030220 platelet extrusion The process in which platelets bud from long processes extended by megakaryocytes. GO:0030221 basophil differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030221 basophil cell differentiation The process in which a relatively unspecialized myeloid precursor cell acquires specialized features of a basophil cell. GO:0030219 megakaryocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030219 megakaryocyte cell differentiation The process in which a myeloid precursor cell acquires specializes features of a megakaryocyte. GO:0030217 T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030217 T-cell differentiation|T-lymphocyte differentiation|T cell development|T lymphocyte differentiation The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex. GO:0030218 erythrocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030218 Wikipedia:Erythropoiesis erythropoiesis|erythrocyte cell differentiation|red blood cell differentiation|RBC differentiation The process in which a myeloid precursor cell acquires specializes features of an erythrocyte. GO:0030215 semaphorin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030215 plexin ligand|plexin binding|semaphorin receptor ligand Interacting selectively and non-covalently with semaphorin receptors. GO:0030216 keratinocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030216 keratinocyte cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a keratinocyte. GO:0030213 hyaluronan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030213 hyaluronan anabolism|hyaluronan synthesis|hyaluronan formation|hyaluronan biosynthesis The chemical reactions and pathways resulting in the formation of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine. GO:0030214 hyaluronan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030214 hyaluronan degradation|hyaluronan catabolism|hyaluronan breakdown The chemical reactions and pathways resulting in the breakdown of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine. CHEBI:149561 phosphatidylethanolamine O-33:2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_149561 RO:0002254 has developmental contribution from biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002254 RO:0002254 x has developmental contribution from y iff x has some part z such that z develops from y CHEBI:149562 phosphatidylethanolamine O-18:2_15:0 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_149562 GO:0005253 anion channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005253 RHEA:34923|Reactome:R-HSA-432034|Reactome:R-HSA-432036 non-selective anion channel activity Enables the energy-independent passage of anions across a lipid bilayer down a concentration gradient. RO:0002255 developmentally contributes to biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002255 RO:0002255 inverse of has developmental contribution from GO:0005254 chloride channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005254 Reactome:R-HSA-975449|Reactome:R-HSA-975340|Reactome:R-HSA-427570|Reactome:R-HSA-2744349 Enables the facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. RO:0002256 developmentally_induced_by biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002256 RO:0002256 t1 developmentally_induced_by t2 if there is a process of organ induction (GO:0001759) with t1 and t2 as interacting participants. t2 causes t1 to change its fate from a precursor tissue type T to T', where T' develops_from T. GO:0005251 delayed rectifier potassium channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005251 Reactome:R-HSA-5577050|Reactome:R-HSA-5577237 Enables the transmembrane transfer of a potassium ion by a delayed rectifying voltage-gated channel. A delayed rectifying current-voltage relation is one where channel activation kinetics are time-dependent, and inactivation is slow. GO:0005252 open rectifier potassium channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005252 Enables the transmembrane transfer of a potassium ion by an open rectifier voltage-gated channel. An open rectifier current-voltage relationship is one in which the direction of rectification depends on the external potassium ion concentration. GO:0005250 A-type (transient outward) potassium channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005250 Reactome:R-HSA-5577234 Enables the transmembrane transfer of a potassium ion by an outwardly-rectifying voltage-gated channel that produces a transient outward current upon a step change in membrane potential. GO:0019898 extrinsic component of membrane biolink:CellularComponent go-plus goslim_metagenomics http://purl.obolibrary.org/obo/GO_0019898 Wikipedia:Peripheral_membrane_protein peripheral membrane protein|extrinsic to membrane The component of a membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:0019899 enzyme binding biolink:MolecularActivity go-plus goslim_drosophila|goslim_generic|goslim_chembl|goslim_yeast http://purl.obolibrary.org/obo/GO_0019899 Interacting selectively and non-covalently with any enzyme. GO:0030211 heparin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030211 heparan sulfate catabolic process|heparin degradation|heparin breakdown|heparin catabolism The chemical reactions and pathways resulting in the breakdown of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues. GO:0019896 axonal transport of mitochondrion biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0019896 axon transport of mitochondria The directed movement of mitochondria along microtubules in nerve cell axons. GO:0019897 extrinsic component of plasma membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019897 juxtamembrane|extrinsic to plasma membrane|peripheral plasma membrane protein The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:0030212 hyaluronan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030212 hyaluronan metabolism The chemical reactions and pathways involving hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine. GO:0019894 kinesin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019894 Interacting selectively and non-covalently and stoichiometrically with kinesin, a member of a superfamily of microtubule-based motor proteins that perform force-generating tasks such as organelle transport and chromosome segregation. GO:0030210 heparin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030210 heparin anabolism|heparan sulfate biosynthetic process|heparin synthesis|heparin formation|heparin biosynthesis The chemical reactions and pathways resulting in the formation of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues. GO:0019895 obsolete kinesin-associated mitochondrial adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019895 OBSOLETE. The activity of linking kinesins, cytoplasmic proteins responsible for moving vesicles and organelles towards the distal end of microtubules, to mitochondria. GO:0019893 obsolete DNA replication inhibitor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019893 DNA replication inhibitor OBSOLETE. (Was not defined before being made obsolete). CHEBI:149558 phosphatidylethanolamine O-33:1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_149558 GO:0030208 dermatan sulfate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030208 dermatan sulfate anabolism|chondroitin sulfate B biosynthetic process|chondroitin sulfate B biosynthesis|dermatan sulfate synthesis|dermatan sulfate formation|dermatan sulfate biosynthesis|dermatan sulphate biosynthesis|dermatan sulphate biosynthetic process The chemical reactions and pathways resulting in the formation of dermatan sulfate, any glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units. GO:0030209 dermatan sulfate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030209 dermatan sulfate breakdown|dermatan sulphate catabolic process|chondroitin sulfate B catabolism|chondroitin sulfate B catabolic process|dermatan sulfate catabolism|dermatan sulphate catabolism|dermatan sulfate degradation The chemical reactions and pathways resulting in the breakdown of dermatan sulfate, any of a group of glycosaminoglycans with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units. CHEBI:149559 phosphatidylethanolamine O-18:1_15:0 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_149559 GO:0030206 chondroitin sulfate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030206 chondroitin sulfate formation|chondroitin sulphate biosynthesis|chondroitin sulphate biosynthetic process|chondroitin sulfate biosynthesis|chondroitin sulfate anabolism|chondroitin sulfate synthesis The chemical reactions and pathways resulting in the formation of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. GO:0030207 chondroitin sulfate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030207 chondroitin sulfate catabolism|chondroitin sulphate catabolism|chondroitin sulfate degradation|chondroitin sulfate breakdown|chondroitin sulphate catabolic process The chemical reactions and pathways resulting in the breakdown of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. GO:0030204 chondroitin sulfate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030204 chondroitin sulphate metabolic process|chondroitin sulphate metabolism|chondroitin sulfate metabolism The chemical reactions and pathways involving chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. They usually occur linked to a protein to form proteoglycans. Two subgroups exist, one in which the sulfate is on the 4-position (chondroitin sulfate A) and the second in which it is in the 6-position (chondroitin sulfate C). They often are polydisperse and often differ in the degree of sulfation from tissue to tissue. The chains of repeating disaccharide are covalently linked to the side chains of serine residues in the polypeptide backbone of a protein by a glycosidic attachment through the trisaccharide unit galactosyl-galactosyl-xylosyl. Chondroitin sulfate B is more usually known as dermatan sulfate. GO:0030205 dermatan sulfate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030205 dermatan sulphate metabolism|chondroitin sulfate B metabolic process|chondroitin sulfate B metabolism|dermatan sulphate metabolic process|dermatan sulfate metabolism The chemical reactions and pathways involving dermatan sulfate, any of a group of glycosaminoglycans with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units. They are important components of ground substance or intercellular cement of skin and some connective tissues. GO:0030202 heparin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030202 heparan sulfate metabolic process|heparin metabolism The chemical reactions and pathways involving heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells. They are similar to heparan sulfates but are of somewhat higher average Mr (6000-20000) and contain fewer N-acetyl groups and more N-sulfate and O-sulfate groups; they may be attached in the same manner to protein, forming proteoglycans. They consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues. GO:0030203 glycosaminoglycan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030203 glycosaminoglycan metabolism The chemical reactions and pathways involving glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars. Formerly known as mucopolysaccharides, they include hyaluronic acid and chondroitin, which provide lubrication in joints and form part of the matrix of cartilage. The three-dimensional structure of these molecules enables them to trap water, which forms a gel and gives glycosaminoglycans their elastic properties. GO:0005267 potassium channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005267 Reactome:R-HSA-1299297|Reactome:R-HSA-1299338|Reactome:R-HSA-1296037|Reactome:R-HSA-1296035|Reactome:R-HSA-1299318|Reactome:R-HSA-2534365|Reactome:R-HSA-1299304|Reactome:R-HSA-1296039|Reactome:R-HSA-1299359|Reactome:R-HSA-1296024|Reactome:R-HSA-5578910|Reactome:R-HSA-1296348 Enables the facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. GO:0005262 calcium channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005262 Reactome:R-HSA-139854|Reactome:R-HSA-139855|Reactome:R-HSA-3295579|Reactome:R-HSA-8949178|Reactome:R-HSA-8949145|Reactome:R-HSA-210420 Enables the facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. GO:0005260 intracellularly ATP-gated chloride channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005260 MetaCyc:3.6.3.49-RXN|EC:5.6.1.6 ATP phosphohydrolase (channel-conductance-controlling)|cystic-fibrosis membrane-conductance-regulating protein activity|ATP-binding and phosphorylation-dependent chloride channel activity|channel-conductance-controlling ATPase activity|cystic fibrosis transmembrane conductance regulator Enables passage of a chloride ion through a transmembrane channel that opens when ATP is bound by the channel complex or one of its constituent parts on the intracellular side of the plasma membrane. CHEBI:149552 emetic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_149552 GO:0005261 cation channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005261 Reactome:R-HSA-1168376|Reactome:R-HSA-1296043|Reactome:R-HSA-169683|Reactome:R-HSA-2089943|Reactome:R-HSA-4420052|Reactome:R-HSA-426223 non-selective cation channel activity|cation diffusion facilitator activity Enables the energy-independent passage of cations across a lipid bilayer down a concentration gradient. CHEBI:149553 anticoronaviral agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_149553 GO:0030200 heparan sulfate proteoglycan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030200 heparan sulfate proteoglycan degradation|heparan sulphate proteoglycan catabolic process|heparan sulfate proteoglycan catabolism|heparan sulfate proteoglycan breakdown|heparan sulphate proteoglycan catabolism|heparin proteoglycan catabolic process The chemical reactions and pathways resulting in the breakdown of proteoglycan containing heparan sulfate, any member of a group of glycosaminoglycans that have repeat units consisting of alternating alpha-(1->4) linked hexuronic acid and glucosamine residues, the former being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter being either sulfated or acetylated on its amino group as well as sulfated on one of its hydroxyl groups. GO:0030201 heparan sulfate proteoglycan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030201 heparan sulphate proteoglycan metabolic process|heparan sulfate proteoglycan metabolism|heparin proteoglycan metabolic process|heparan sulphate proteoglycan metabolism The chemical reactions and pathways involving any proteoglycan containing heparan sulfate, any member of a group of glycosaminoglycans that have repeat units consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues, the former being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter being either sulfated or acetylated on its amino group as well as sulfated on one of its hydroxyl groups. GO:0005237 inhibitory extracellular ligand-gated ion channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005237 Enables the transmembrane transfer of an ion by a channel that opens when a specific extracellular inhibitory ligand has been bound by the channel complex or one of its constituent parts. Inhibitory ligands, such as GABA or glycine, open chloride-selective channels. RO:0002231 has start location biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002231 RO:0002231 x 'has starts location' y if and only if there exists some process z such that x 'starts with' z and z 'occurs in' y GO:0005234 extracellularly glutamate-gated ion channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005234 extracellular-glutamate-gated ion channel activity Enables the transmembrane transfer of an ion by a channel that opens when glutamate is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane. RO:0002232 has end location biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002232 RO:0002232 x 'has end location' y if and only if there exists some process z such that x 'ends with' z and z 'occurs in' y CHEBI:149540 5-deoxy-D-ribofuranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_149540 RO:0002233 has input biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002233 RO:0002233 p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p. GO:0005231 excitatory extracellular ligand-gated ion channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005231 Reactome:R-HSA-399712|Reactome:R-HSA-432164|Reactome:R-HSA-399711|Reactome:R-HSA-420980|Reactome:R-HSA-438037 Enables the transmembrane transfer of an ion by a channel that opens when a specific extracellular ligand has been bound by the channel complex or one of its constituent parts, where channel opening contributes to an increase in membrane potential. RO:0002234 has output biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002234 RO:0002234 p has output c iff c is a participant in p, c is present at the end of p, and c is not present at the beginning of p. GO:0005232 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005232 CHEBI:149543 L-altrose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_149543 GO:0005230 extracellular ligand-gated ion channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005230 Enables the transmembrane transfer of an ion by a channel that opens when a specific extracellular ligand has been bound by the channel complex or one of its constituent parts. RO:0002230 ends with biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002230 RO:0002230 x ends with y if and only if x has part y and the time point at which x ends is equivalent to the time point at which y ends. Formally: α(y) > α(x) ∧ ω(y) = ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. RO:0002229 ends biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002229 RO:0002229 finishes Relation between occurrents, shares an end boundary with. GO:0019878 lysine biosynthetic process via aminoadipic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019878 lysine biosynthesis, aminoadipic acid pathway|lysine biosynthetic process, aminoadipic acid pathway|lysine biosynthetic process, aminoadipic pathway|lysine biosynthesis, aminoadipic pathway|lysine formation via aminoadipic acid|lysine synthesis via aminoadipic acid|lysine anabolism via aminoadipic acid The chemical reactions and pathways resulting in the formation of lysine by the aminoadipic pathway. RO:0002224 starts with biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002224 RO:0002224 x starts with y if and only if x has part y and the time point at which x starts is equivalent to the time point at which y starts. Formally: α(y) = α(x) ∧ ω(y) < ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. RO:0002225 develops_from_part_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002225 RO:0002225 GO:0019879 peptidyl-thyronine biosynthetic process from peptidyl-tyrosine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019879 peptidyl-thyronine formation from peptidyl-tyrosine|peptidyl-thyronine synthesis from peptidyl-tyrosine|peptidyl-thyronine anabolism from peptidyl-tyrosine The formation of peptidyl-thyronine from peptidyl-tyrosine in thyroglobulin by phenyl transfer coupled with the formation of peptidyl-dehydroalanine. RO:0002226 develops_in biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002226 RO:0002226 GO:0019876 nylon catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019876 nylon degradation|nylon breakdown|nylon catabolism The chemical reactions and pathways resulting in the breakdown of nylon, a polymer where the main polymer chain comprises recurring amide groups; these compounds are generally formed from combinations of diamines, diacids and amino acids. GO:0019877 diaminopimelate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019877 diaminopimelate anabolism|diaminopimelate synthesis|diaminopimelate formation|diaminopimelate biosynthesis The chemical reactions and pathways resulting in the formation of diaminopimelate, both as an intermediate in lysine biosynthesis and as a component (as meso-diaminopimelate) of the peptidoglycan of Gram-negative bacterial cell walls. GO:0019874 6-aminohexanoate-cyclic-dimer hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019874 UM-BBD_reactionID:r1097|RHEA:16225|MetaCyc:3.5.2.12-RXN|KEGG_REACTION:R03448|EC:3.5.2.12 1,8-diazacyclotetradecane-2,9-dione lactamhydrolase activity Catalysis of the reaction: 1,8-diazacyclotetradecane-2,9-dione + H(2)O = N-(6-aminohexanoyl)-6-aminohexanoate. GO:0019875 6-aminohexanoate-dimer hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019875 MetaCyc:RXN-3962|UM-BBD_enzymeID:e0673|EC:3.5.1.46|RHEA:21364 6-aminohexanoic acid oligomer hydrolase activity|N-(6-aminohexanoyl)-6-aminohexanoate amidohydrolase activity Catalysis of the reaction: N-(6-aminohexanoyl)-6-aminohexanoate + H2O = 2 6-aminohexanoate. GO:0019872 streptomycin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019872 streptomycin biosynthesis|streptomycin anabolism|streptomycin synthesis|streptomycin formation The chemical reactions and pathways resulting in the formation of streptomycin, a commonly used antibiotic in cell culture media; it acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome. GO:0019873 obsolete tellurium sensitivity/resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019873 tellurium sensitivity/resistance OBSOLETE. (Was not defined before being made obsolete). GO:0019870 potassium channel inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019870 Stops, prevents, or reduces the activity of a potassium channel. GO:0019871 sodium channel inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019871 Stops, prevents, or reduces the activity of a sodium channel. GO:0005248 voltage-gated sodium channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005248 Reactome:R-HSA-5576895 voltage gated sodium channel activity|voltage-dependent sodium channel activity|voltage-gated sodium ion channel activity|voltage-sensitive sodium channel Enables the transmembrane transfer of a sodium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. GO:0005249 voltage-gated potassium channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005249 Reactome:R-HSA-1296127 voltage-dependent potassium channel activity|voltage-gated potassium ion channel activity|voltage gated potassium channel activity|voltage-sensitive potassium channel Enables the transmembrane transfer of a potassium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. GO:0005246 calcium channel regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005246 Modulates the activity of a calcium channel. GO:0005247 voltage-gated chloride channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005247 Reactome:R-HSA-2744228 voltage gated chloride channel activity|voltage-dependent chloride channel activity Enables the transmembrane transfer of a chloride ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. GO:0005244 voltage-gated ion channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005244 voltage-dependent ion channel activity|voltage gated ion channel activity Enables the transmembrane transfer of an ion by a voltage-gated channel. An ion is an atom or group of atoms carrying an electric charge by virtue of having gained or lost one or more electrons. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. RO:0002220 adjacent to biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002220 RO:0002220 x adjacent_to y iff: x and y share a boundary GO:0005245 voltage-gated calcium channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005245 Reactome:R-HSA-9701141|Reactome:R-HSA-265645|Reactome:R-HSA-9701055|Reactome:R-HSA-5577213 voltage gated calcium channel activity|depolarization-activated voltage-gated calcium channel|depolarization-activated voltage gated calcium channel activity|voltage-sensitive calcium channel|dihydropyridine-sensitive calcium channel activity|voltage-dependent calcium channel activity|depolarization-activated calcium channel|voltage-gated calcium ion channel activity|depolarization-activated voltage-gated calcium channel activity Enables the transmembrane transfer of a calcium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. RO:0002221 surrounds biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002221 RO:0002221 inverse of surrounded_by GO:0005242 inward rectifier potassium channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005242 Reactome:R-HSA-5678418|Reactome:R-HSA-1296046|Reactome:R-HSA-1369017|Reactome:R-HSA-5678261|Reactome:R-HSA-1296045 Kir channel activity Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force. The inward-rectification is due to a voltage-dependent block of the channel pore by a specific ligand or ligands, and as a result the macroscopic conductance depends on the difference between membrane voltage and the K+ equilibrium potential rather than on membrane voltage itself. RO:0002222 temporally related to biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002222 RO:0002222 RO:0002223 starts biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002223 RO:0002223 inverse of starts with GO:0005243 gap junction channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005243 Reactome:R-HSA-375340|Reactome:R-HSA-375330|Reactome:R-HSA-190681|Reactome:R-HSA-375342|Reactome:R-HSA-375339 innexin|connexin|intercellular channel|innexin channel activity A wide pore channel activity that enables a direct cytoplasmic connection from one cell to an adjacent cell. The gap junction can pass large solutes as well as electrical signals between cells. Gap junctions consist of two gap junction hemi-channels, or connexons, one contributed by each membrane through which the gap junction passes. GO:0005240 obsolete glycine receptor-associated protein biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005240 glycine receptor-associated protein OBSOLETE. (Was not defined before being made obsolete). GO:0005241 obsolete inward rectifier channel biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005241 inward rectifier channel OBSOLETE. (Was not defined before being made obsolete). RO:0002219 surrounded_by biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002219 RO:0002219 x surrounded_by y iff: x is adjacent to y and for every region r adjacent to x, r overlaps y RO:0002213 positively regulates biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002213 RO:0002213 Process(P1) postively regulates process(P2) iff: P1 initiates P2, or P1 increases the the frequency of initiation of P2 or the magnitude or rate of output of P2. GO:0019889 pteridine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019889 pteridine metabolism The chemical reactions and pathways involving pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group. RO:0002215 capable of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002215 RO:0002215 A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process. GO:0019887 protein kinase regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019887 Modulates the activity of a protein kinase, an enzyme which phosphorylates a protein. GO:0019888 protein phosphatase regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019888 Reactome:R-HSA-180038 protein phosphatase type 1 regulator activity|protein phosphatase type 4 regulator activity|protein phosphatase 2 regulator activity|protein phosphatase 3 regulator activity|protein phosphatase type 2A regulator activity|protein phosphatase type 2B regulator activity|calcineurin, intrinsic regulator activity|protein phosphatase type 2B, intrinsic regulator activity|protein phosphatase type 2A, intrinsic regulator activity|calcineurin regulator activity|protein phosphatase 3, intrinsic regulator activity|protein phosphatase 2, intrinsic regulator activity|protein phosphatase type 4, intrinsic regulator activity|protein phosphatase type 1, intrinsic regulator activity Modulates the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule. RO:0002216 capable of part of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002216 RO:0002216 c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p. GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019885 endogenous peptide antigen processing and presentation via MHC class I|antigen processing, endogenous antigen via major histocompatibility complex class I|antigen presentation, endogenous peptide antigen|antigen processing, endogenous antigen via MHC class I The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules. GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019886 antigen presentation, exogenous peptide antigen|exogenous peptide antigen processing and presentation via MHC class II|antigen presentation, exogenous antigen via MHC class II|antigen processing, exogenous antigen via major histocompatibility complex class II The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein. GO:0019883 antigen processing and presentation of endogenous antigen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019883 antigen presentation, endogenous antigen The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of endogenous origin on its cell surface in association with an MHC protein complex. GO:0019884 antigen processing and presentation of exogenous antigen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019884 antigen presentation, exogenous antigen The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of exogenous origin on its cell surface in association with an MHC protein complex. GO:0019881 obsolete streptomycin susceptibility/resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019881 streptomycin susceptibility/resistance OBSOLETE. (Was not defined before being made obsolete). GO:0019882 antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019882 Wikipedia:Antigen_presentation antigen presentation|antigen processing The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. GO:0019880 obsolete bacteriocin susceptibility/resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019880 bacteriocin susceptibility/resistance OBSOLETE. (Was not defined before being made obsolete). GO:0044820 mitotic telomere tethering at nuclear periphery biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044820 The process in which a telomere is maintained in a specific location at the nuclear periphery, as part of a mitotic cell cycle. RO:0002211 regulates biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002211 RO:0002211 process(P1) regulates process(P2) iff: P1 results in the initiation or termination of P2 OR affects the frequency of its initiation or termination OR affects the magnitude or rate of output of P2. RO:0002212 negatively regulates biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002212 RO:0002212 Process(P1) negatively regulates process(P2) iff: P1 terminates P2, or P1 descreases the the frequency of initiation of P2 or the magnitude or rate of output of P2. GO:0044827 modulation by host of viral genome replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044827 regulation by host of viral genome reproduction A process in which a host organism modulates the frequency, rate or extent of viral genome replication. GO:0044828 negative regulation by host of viral genome replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044828 A process in which a host organism stops, prevents or reduces the frequency, rate or extent of viral genome replication. RO:0002207 directly_develops_from biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002207 RO:0002207 GO:0044825 retroviral strand transfer activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044825 strand transfer reaction Catalysis of the covalent insertion of processed 3'-viral DNA ends into host chromosomal DNA by a trans-esterification reaction. GO:0044826 viral genome integration into host DNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044826 viral genome integration The insertion into a host genome of viral DNA, usually by the action of an integrase enzyme. Once integrated, the provirus persists in the host cell and serves as a template for the transcription of viral genes and replication of the viral genome, leading to the production of new viruses. GO:0044823 retroviral integrase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044823 Catalysis of the covalent insertion of double-stranded retroviral DNA into host DNA. Proceeds by an endonucleolytic cleavage at each 3'-OH extremity of the viral genome, named 3'-processing, followed by a strand transfer reaction leading to the insertion of the processed viral DNA into the target DNA by a trans-esterification mechanism. RO:0002202 develops from biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002202 RO:0002202 x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y CHEBI:18515 (1S,2S,4R)-limonene-1,2-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18515 RO:0002203 develops_into biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002203 RO:0002203 inverse of develops from GO:0044824 retroviral 3' processing activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044824 3'-processing activity|3' processing reaction The catalysis of the removal of two di- or tri-nucleotides from each 3' end of double-stranded viral DNA, exposing recessed 3' hydroxyls. GO:0044821 meiotic telomere tethering at nuclear periphery biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044821 The process in which a telomere is maintained in a specific location at the nuclear periphery, as part of a meiotic cell cycle. GO:0044822 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044822 GO:0044829 positive regulation by host of viral genome replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044829 A process in which a host organism activates or increases the frequency, rate or extent of viral genome replication. PR:000018550 fractalkine proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000018550 CX3CL1/ClvPrd A fractalkine that has been processed by proteolytic cleavage. GO:0044830 modulation by host of viral RNA genome replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044830 regulation by host of viral RNA genome replication A process in which a host organism modulates the frequency, rate or extent of viral RNA genome replication. GO:0044831 modulation by virus of host cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044831 Any process in which a virus modulates the frequency, rate or extent of cytokine production in its host organism. GO:0044838 cell quiescence biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044838 cellular quiescence|quiescence|cell cycle quiescence|G0 phase A specialized resting state that cells enter in response to cues from the cell's environment. Quiescence is characterized by the absence of cell growth and division, by a reprogramming of global gene expression, and by changes characteristic of the organism and specific cell type. Depending on external conditions, quiescence may persist until cell death or cells may resume cell growth and division. In some cell types or under certain conditions, cellular metabolism may proceed. GO:0044839 cell cycle G2/M phase transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044839 The cell cycle process by which a cell in G2 phase commits to M phase. GO:0044836 D-xylose fermentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044836 The anaerobic enzymatic conversion of D-xylose to ethanol, yielding energy in the form of ATP. GO:0044837 actomyosin contractile ring organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044837 cytokinesis, actomyosin contractile ring organization A process which results in the assembly, arrangement of constituent parts, or disassembly of an actomyosin contractile ring. GO:0044834 retroviral intasome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044834 A tetramer of retroviral integrase subunits tightly associated with a pair of viral DNA ends. Functions to insert viral DNA into a host cell chromosome. CHEBI:18504 (1->3,1->4)-beta-D-glucan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18504 GO:0044835 hydrogen generation via nitrogenase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044835 The chemical reactions and pathways resulting in the formation of H2 (dihydrogen) which involve a nitrogenase activity as one of the steps. This process is observed in cyanobacteria. GO:0044832 induction by virus of host cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044832 positive regulation by virus of host cytokine production The process in which a virus increases the frequency, rate or extent of cytokine production in its host organism. GO:0044833 modulation by virus of host protein transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044833 Any viral process that modulates the frequency, rate or extent of protein transport in its host organism. GO:0044841 gut granule membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044841 The membrane of a gut granule, a lysosome-related organelle contained within the intestinal cells of the nematode C. elegans. GO:0044842 gut granule lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044842 The lumen of a gut granule, a lysosome-related organelle contained within the intestinal cells of the nematode C. elegans. GO:0044840 gut granule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044840 A lysosome-related organelle contained within the intestinal cells of the nematode C. elegans. Gut granules are acidified, birefringent, autofluorescent, and contain the vacuolar H+-ATPase. They also serve as sites of cellular zinc storage. GO:0044849 estrous cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044849 Wikipedia:Estrous_cycle A type of ovulation cycle, which occurs in most mammalian therian females, where the endometrium is resorbed if pregnancy does not occur. GO:0044847 iron acquisition from host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044847 iron acquisition by symbiont from host|heme acquisition|iron acquisition by symbiont from host heme|acquisition by organism of nutrients from host via siderophores|acquisition by symbiont of nutrients from host via siderophores|iron acquisition The process by which a symbiont acquires iron from its host, either from heme or other iron containing molecules such as transferrin and lactoferrin. Begins with either the secretion of symbiont gene products that bind iron- or heme-containing molecules (siderophores and hemophores) from the symbiont cell into the host, or by expression of receptors that bind iron- or heme-containing molecules on the symbiont cell surface. Ends when the iron-containing compound is transported into the symbiont cell. GO:0044848 biological phase biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0044848 A distinct period or stage in a biological process or cycle. GO:0044845 chain elongation of O-linked mannose residue biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044845 Extension of the O-linked mannose residue of a mannoprotein by the stepwise addition of further mannose molecules. GO:0044846 negative regulation by symbiont of indole acetic acid levels in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044846 negative regulation by symbiont of IAA levels in host|negative regulation by symbiont of auxin levels in host Any process in which an organism reduces the indole acetic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0044843 cell cycle G1/S phase transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044843 The cell cycle process by which a cell in G1 phase commits to S phase. GO:0044844 meiotic interphase II biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044844 The cell cycle phase which begins at the end of meiosis I cytokinesis and ends when meiosis II prophase begins. During meiotic interphase II no DNA replication takes place, but the centrioles duplicate and spindle fibres emerge. CHEBI:18533 5alpha-campestan-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18533 CHEBI:18534 campest-4-en-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18534 PR:000018513 proteinase-activated receptor 1 proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000018513 F2R/ClvPrd A proteinase-activated receptor 1 that has been processed by proteolytic cleavage. GO:0044852 nonrepetitive DNA condensation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044852 nonrepetitive DNA packaging The process in which chromatin structure of nonrepetitive regions of DNA is compacted prior to and during mitosis in eukaryotic cells. GO:0044853 plasma membrane raft biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044853 A membrane raft that is part of the plasma membrane. GO:0044850 menstrual cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044850 Wikipedia:Menstrual_cycle A type of ovulation cycle where the endometrium is shed if pregnancy does not occur. GO:0044851 hair cycle phase biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044851 The cyclical periods of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body. GO:0044858 plasma membrane raft polarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044858 The clustering and aggregation of plasma membrane rafts at a single cellular pole during activation of particular cell types, such as lymphocytes. GO:0044859 protein insertion into plasma membrane raft biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044859 The process in which a protein is incorporated into a plasma membrane raft. GO:0044856 plasma membrane raft localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044856 Any process in which plasma membrane rafts are transported to, or maintained in, a specific location. GO:0044857 plasma membrane raft organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044857 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of plasma membrane rafts. GO:0044854 plasma membrane raft assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044854 The aggregation, arrangement and bonding together of a set of components to form a plasma membrane raft. GO:0044855 plasma membrane raft distribution biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044855 The process that establishes the spatial arrangement of membrane rafts within a plasma membrane. CHEBI:609827 L-canavanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_609827 GO:0044863 modulation by virus of host cell division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044863 regulation by virus of host cell division Any process where an infecting virus modulates the frequency, rate or extent of the physical partitioning and separation of its host's cell into daughter cells. GO:0044864 positive regulation by virus of host cell division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044864 Any process where an infecting virus activates or increases the frequency, rate or extent of its host's cell division. GO:0044861 protein transport into plasma membrane raft biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044861 The directed movement of a protein into a plasma membrane raft. GO:0044862 protein transport out of plasma membrane raft biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044862 The directed movement of a protein out of a plasma membrane raft. GO:0044860 protein localization to plasma membrane raft biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044860 A process in which a protein is transported to, or maintained in, a location within a plasma membrane raft. GO:0030291 protein serine/threonine kinase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030291 Stops, prevents or reduces the activity of a protein serine/threonine kinase. GO:0030292 protein tyrosine kinase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030292 Stops, prevents or reduces the activity of a protein tyrosine kinase. GO:0044869 negative regulation by host of viral exo-alpha-sialidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044869 The process in which a host organism decreases viral exo-alpha-sialidase activity, the catalysis of the hydrolysis of peptide bonds in a protein. GO:0030290 sphingolipid activator protein activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030290 Reactome:R-HSA-1605717 saposin Any of a group of peptide cofactors of enzymes for the lysosomal degradation of sphingolipids. They stimulate various enzymes, including glucosylceramidase, galactosylceramidase, cerebroside-sulfatase, alpha-galactosidase, beta-galactosidase, and sphingomyelin phosphodiesterase. GO:0044867 modulation by host of viral catalytic activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044867 The process in which a host organism effects a change in the enzyme activity of a virus with which it is infected. GO:0044868 modulation by host of viral molecular function biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044868 A process in which a host organism modulates the frequency, rate or extent of any molecular function being mediated by a virus with which it is infected. GO:0044865 negative regulation by virus of host cell division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044865 inhibition by virus of host cell division Any process where an infecting virus stops, prevents, or reduces the frequency, rate or extent of its host's cell division. GO:0044866 modulation by host of viral exo-alpha-sialidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044866 The process in which a host organism effects a change in viral exo-alpha-sialidase activity, the catalysis of the hydrolysis of peptide bonds in a protein. GO:0030299 intestinal cholesterol absorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030299 Uptake of cholesterol into the blood by absorption from the small intestine. GO:0030297 transmembrane receptor protein tyrosine kinase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030297 Binds to and increases the activity of a transmembrane receptor protein tyrosine kinase. GO:0030298 receptor signaling protein tyrosine kinase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030298 receptor signalling protein tyrosine kinase activator activity Binds to and increases the activity of a receptor signaling protein tyrosine kinase. GO:0030295 protein kinase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030295 Binds to and increases the activity of a protein kinase, an enzyme which phosphorylates a protein. GO:0030296 protein tyrosine kinase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030296 Increases the activity of a protein tyrosine kinase, an enzyme which phosphorylates a tyrosyl phenolic group on a protein. GO:0030293 transmembrane receptor protein tyrosine kinase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030293 Stops, prevents or reduces the activity of a transmembrane receptor protein tyrosine kinase. GO:0030294 receptor signaling protein tyrosine kinase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030294 receptor signalling protein tyrosine kinase inhibitor activity Stops, prevents or reduces the activity of a receptor signaling protein tyrosine kinase. GO:0044874 lipoprotein localization to outer membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044874 A process in which a lipoprotein is transported to, or maintained in, a specific location in an outer membrane. GO:0044875 gamma-glutamyl hercynylcysteine sulfoxide synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044875 RHEA:42672|EC:1.14.99.50 gamma-glutamyl hercynylcysteine S-oxide synthase|gamma-glutamyl hercynylcysteine sulfoxide synthase Catalysis of the reaction: gamma-glutamyl cysteine + hercynine + O2 <=> gamma-glutamyl-hercynyl cysteine sulfoxide + H2O. GO:0044872 lipoprotein localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044872 Any process in which a lipoprotein is transported to, or maintained in, a specific location. GO:0044873 lipoprotein localization to membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044873 A process in which a lipoprotein is transported to, or maintained in, a specific location in a membrane. GO:0044870 modulation by host of viral glycoprotein metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044870 A process in which a host organism modulates the frequency, rate or extent of viral glycoprotein metabolic process. GO:0044871 negative regulation by host of viral glycoprotein metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044871 A process in which a host organism stops, prevents or reduces the frequency, rate or extent of viral glycoprotein metabolic process. GO:0030280 structural constituent of skin epidermis biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030280 structural constituent of epidermis The action of a molecule that contributes to the structural integrity of an epidermal cutaneous structure. GO:0030281 structural constituent of cutaneous appendage biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030281 The action of a molecule that contributes to the structural integrity of cutaneous epidermal structures such as hairs, scales, or feathers. GO:0044878 mitotic cytokinesis checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044878 cytokinesis after mitosis checkpoint|defective cytokinesis checkpoint A mitotic cell cycle checkpoint that detects a defect in cytokinesis and prevents further rounds of nuclear division until cytokinesis is completed. GO:0044879 morphogenesis checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044879 septin checkpoint A mitotic cell cycle checkpoint which delays mitotic onset in response to perturbations that affect cell shape via the actin cytoskeleton, septin organization, small cell size, and/or the extent of membrane growth. GO:0044876 hercynylselenocysteine synthase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044876 RHEA:42683|MetaCyc:RXN-15803 Catalysis of the reaction: 2 L-selenocysteine + 2 hercynine + O2 <=> 2 H2O + 2 hercynylselenocysteine. GO:0044877 protein-containing complex binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0044877 protein complex binding|macromolecular complex binding Interacting selectively and non-covalently with a macromolecular complex. GO:0030288 outer membrane-bounded periplasmic space biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030288 Wikipedia:Periplasmic_space outer membrane-enclosed periplasmic space|outer membrane bounded periplasmic space The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall. GO:0030289 protein phosphatase 4 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030289 A protein serine/threonine phosphatase complex formed by the catalytic subunit of protein phosphatase 4 plus one or more regulatory subunits. GO:0030286 dynein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030286 Any of several large complexes that contain two or three dynein heavy chains and several light chains, and have microtubule motor activity. GO:0030287 cell wall-bounded periplasmic space biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030287 cell wall bounded periplasmic space|inner wall zone|cell wall-enclosed periplasmic space|IWZ The region between the plasma membrane and the cell wall in organisms lacking an outer cell membrane such as yeast and Gram positive bacteria. The region is thinner than the equivalent in Gram negative bacteria. GO:0030284 estrogen receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030284 Combining with estrogen and transmitting the signal within the cell to trigger a change in cell activity or function. GO:0030285 integral component of synaptic vesicle membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0030285 integral to synaptic vesicle membrane The component of the synaptic vesicle membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0030282 bone mineralization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030282 bone calcification The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue. GO:0030283 testosterone dehydrogenase [NAD(P)] activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030283 MetaCyc:1.1.1.51-RXN|EC:1.1.1.51|Reactome:R-HSA-193064 17beta-hydroxy steroid dehydrogenase|3beta-hydroxysteroid dehydrogenase|3(or 17)beta-hydroxysteroid:NAD(P)+ oxidoreductase|beta-hydroxy steroid dehydrogenase|3beta-hydroxy steroid dehydrogenase|3(or 17)beta-hydroxysteroid dehydrogenase activity Catalysis of the reaction: testosterone + NAD(P)+ = androst-4-ene-3,17-dione + NAD(P)H + H+. GO:0030279 negative regulation of ossification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030279 negative regulation of bone formation|down-regulation of ossification|negative regulation of bone biosynthesis|downregulation of ossification|down regulation of ossification|inhibition of ossification Any process that stops, prevents, or reduces the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance. GO:0030270 formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030270 UM-BBD_reactionID:r0346|MetaCyc:2.3.1.101-RXN|EC:2.3.1.101|KEGG_REACTION:R03390|RHEA:18061 formylmethanofuran:5,6,7,8-tetrahydromethanopterin 5-formyltransferase activity|FTR|formylmethanofuran:tetrahydromethanopterin formyltransferase activity|formylmethanofuran:5,6,7,8-tetrahydromethanopterin N5-formyltransferase activity|N-formylmethanofuran(CHO-MFR):tetrahydromethanopterin(H4MPT) formyltransferase activity|formylmethanofuran-tetrahydromethanopterin formyltransferase activity Catalysis of the reaction: 5,6,7,8-tetrahydromethanopterin + N-formylmethanofuran + H(+) = N(5)-formyl-5,6,7,8-tetrahydromethanopterin + methanofuran. GO:0030277 maintenance of gastrointestinal epithelium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030277 Protection of epithelial surfaces of the gastrointestinal tract from proteolytic and caustic digestive agents. GO:0030278 regulation of ossification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030278 regulation of bone biosynthesis|regulation of bone formation Any process that modulates the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance. GO:0030275 LRR domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030275 Interacting selectively and non-covalently with a LRR domain (leucine rich repeats) of a protein. GO:0030276 clathrin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030276 Interacting selectively and non-covalently with a clathrin heavy or light chain, the main components of the coat of coated vesicles and coated pits, and which also occurs in synaptic vesicles. GO:0030273 melanin-concentrating hormone receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030273 MCH receptor Combining with the cyclic peptide hormone melanin-concentrating hormone to initiate a change in cell activity. GO:0030274 LIM domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030274 Interacting selectively and non-covalently with a LIM domain (for Lin-11 Isl-1 Mec-3) of a protein, a domain with seven conserved cysteine residues and a histidine, that binds two zinc ions and acts as an interface for protein-protein interactions. GO:0030271 obsolete chymase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030271 chymase activity|skeletal muscle (SK) protease activity|skin chymotryptic proteinase|SK protease activity|mast cell protease I activity|mast cell serine proteinase|skeletal muscle protease OBSOLETE. Catalysis of the preferential cleavage: Phe-Xaa > Tyr-Xaa > Trp-Xaa > Leu-Xaa. GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030272 Reactome:R-HSA-6801342|RHEA:10488|KEGG_REACTION:R02301|EC:6.3.3.2|MetaCyc:5-FORMYL-THF-CYCLO-LIGASE-RXN 5-Formyltetrahydrofolate cyclodehydrase activity|5-formyltetrahydrofolate cyclodehydrase|5-formyltetrahydrofolate cyclo-ligase (ADP-forming)|formyltetrahydrofolic cyclodehydrase activity|methenyl-THF synthetase activity|5,10-methenyltetrahydrofolate synthetase activity Catalysis of the reaction: 5-formyltetrahydrofolate + ATP = 5,10-methenyltetrahydrofolate + ADP + H(+) + phosphate. GO:0030268 methylenetetrahydromethanopterin dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030268 RHEA:16721|EC:1.5.98.1|UM-BBD_reactionID:r0348|MetaCyc:1.5.99.9-RXN|KEGG_REACTION:R04456 N(5),N(10)-methylenetetrahydromethanopterin dehydrogenase activity|5,10-methylenetetrahydromethanopterin:coenzyme-F420 oxidoreductase activity|5,10-methylenetetrahydromethanopterin dehydrogenase activity Catalysis of the reaction: 5,10-methylenetetrahydromethanopterin + coenzyme F420 + 2 H(+) = 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + reduced coenzyme F420. GO:0030269 tetrahydromethanopterin S-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030269 RHEA:53492|MetaCyc:2.1.1.86-RXN|EC:2.1.1.86|UM-BBD_reactionID:r0355|KEGG_REACTION:R04347 N5-methyltetrahydromethanopterin--coenzyme M methyltransferase activity|N(5)-methyltetrahydromethanopterin--coenzyme M methyltransferase activity|tetrahydromethanopterin methyltransferase activity|5-methyl-5,6,7,8-tetrahydromethanopterin:2-mercaptoethanesulfonate 2-methyltransferase activity Catalysis of the reaction: 5-methyltetrahydromethanopterin + coenzyme M = 5,6,7,8-tetrahydromethanopterin + methyl-coenzyme M. 2-(methylthio)ethanesulfonate is also known as methyl-CoM. NCBITaxon:1437010 Boreoeutheria organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_1437010 Boreotheria GO:0030266 quinate 3-dehydrogenase (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030266 RHEA:22364|MetaCyc:QUINATE-5-DEHYDROGENASE-RXN|EC:1.1.1.282|EC:1.1.1.24|KEGG_REACTION:R01872 quinate:NAD(+) 3-oxidoreductase activity|quinate:NAD(+) 5-oxidoreductase activity|quinate:NAD 3-oxidoreductase activity|quinate:NAD 5-oxidoreductase activity|quinic dehydrogenase activity Catalysis of the reaction: (-)-quinate + NAD+ = (-)-3-dehydroquinate + NADH + H+. GO:0030267 glyoxylate reductase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030267 MetaCyc:GLYOXYLATE-REDUCTASE-NADP+-RXN|Reactome:R-HSA-389826|EC:1.1.1.79|RHEA:10992|Wikipedia:Glyoxylate_reductase_(NADP+) NADPH-glyoxylate reductase activity|glyoxylate reductase (NADP+)|glycolate:NADP+ oxidoreductase activity Catalysis of the reaction: glycolate + NADP+ = glyoxylate + NADPH + H+. GO:0030264 nuclear fragmentation involved in apoptotic nuclear change biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030264 nucleus fragmentation|nuclear fragmentation during apoptosis|apoptotic nuclear fragmentation The breakdown of the nucleus into small membrane-bounded compartments, or blebs, each of which contain compacted DNA. GO:0030265 phospholipase C-activating rhodopsin mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030265 phospholipase C-activating rhodopsin mediated G-protein coupled receptor signaling pathway|rhodopsin mediated G protein signaling, coupled to IP3 second messenger|PLC-activating rhodopsin mediated signaling pathway|rhodopsin mediated G protein signalling, coupled to IP3 second messenger|rhodopsin mediated G-protein signalling, coupled to IP3 second messenger|rhodopsin mediated G-protein signaling, coupled to IP3 second messenger The series of molecular signals generated as a consequence of a rhodopsin molecule being activated by a photon, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG). GO:0030262 apoptotic nuclear changes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030262 apoptotic nuclear change Alterations undergone by nuclei at the molecular and morphological level as part of the execution phase of apoptosis. GO:0030263 apoptotic chromosome condensation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030263 Wikipedia:Pyknosis pyknosis The compaction of chromatin during apoptosis. GO:0030260 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030260 GO:0030261 chromosome condensation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030261 DNA condensation|eukaryotic chromosome condensation|nuclear chromosome condensation The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells. CHEBI:18481 (-)-cis-sabinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18481 UBERON:0018664 neck of bone element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018664 bone neck|neck of bone the neck region of a bone organ. CHEBI:43445 (+)-aristolochene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_43445 UBERON:0018667 neck of scapula biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018667 scapular neck|anatomical neck of scapula UBERON:0004022 germinal neuroepithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004022 germinal neuroepithelial layer|germinal neuroepithelium|original neural tube The single layer of epithelial cells that lines the early neural tube and develops into the nervous system and into the neural crest cells UBERON:0004023 ganglionic eminence biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004023 GE|fetal subventricular zone|SVZ|embryonic subventricular zone|embryonic SVZ|subventricular zone|subependymal layer|embryonic GE|embryonic/fetal subventricular zone The transient proliferative population of neurons that expands exponentially during late prenatal development; it is a continuous germinal zone distinct from the ventricular zone that surrounds the brain ventricles[MP]. UBERON:0004021 spongiotrophoblast layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004021 spongiotrophoblast layer of placenta|spongiotrophoblast The structure of the outer structural layer of the rodent placenta[MP]. UBERON:0004027 chorionic plate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004027 That portion of the chorionic wall in the region of its uterine attachment, which gives rise to chorionic villi; it consists of the mesoderm that lines the chorionic vesicle and, on the maternal side, of the trophoblast that lines the intervillous spaces; in the last half of gestation, the mesodermal connective tissue is largely replaced by fibrinoid material, and the amnionic membrane is adherent to the fetal side of the plate. CHEBI:43433 L-alloisoleucine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_43433 UBERON:0018657 pupal case biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018657 Any acellular shell or covering that surrounds the pupal form of an insect UBERON:0004015 embryonic-extraembryonic boundary biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004015 The connection between the embryo proper and extraembryonic tissues UBERON:0004016 dermatome biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004016 epimere mesoderm|cutis plate|mesenchyma dermatomiale|dermatomal mesenchyme A transitional population of migrating mesenchymal cells that derive from somites and that will become dermal cells. UBERON:0018649 cardiac muscle tissue of ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018649 ventricular cardiac muscle tissue|ventricular muscle|ventricular heart muscle UBERON:0004000 tarsal gland acinus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004000 Meibomian gland acinus|palpebral gland acinus|acinus of tarsal gland A sac-like structure comprising a sebaceous gland. UBERON:0004001 olfactory bulb layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004001 cytoarchitectural part of olfactory bulb . CHEBI:43419 isoursodeoxycholic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_43419 NCBITaxon:6236 Rhabditida organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_6236 NCBITaxon:6237 Caenorhabditis organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_6237 UBERON:0004066 frontonasal prominence biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004066 frontonasal mass|prominentia frontonasalis|forebrain prominence|embryonic frontonasal prominence|frontonasal process The unpaired embryonic prominence that is formed by the tissues surrounding the forebrain vesicle and develops into the forehead and bridge of the nose/snout. UBERON:0004067 lateral nasal prominence biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004067 lateral nasal swelling|lateral nasal process|latero-nasal process|prominentia nasalis lateralis The lateral area of the two branches of a horseshoe-shaped mesenchymal swelling in the future nasal region of the embryo; it separates the olfactory pit from the developing eye and the ala of the nose/snout develops from it UBERON:0004064 neural tube basal plate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004064 ventral part of neural tube|spinal cord basal plate|basal plate of neural tube|motor part of neural tube|basal plate The region of the mantle layer of the neural tube that lies ventral to the sulcus limitans and contains primarily motor neurons and interneurons. UBERON:0004062 neural tube marginal layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004062 brain marginal zone|neural tube marginal zone The outermost layer of the neural tube that consists of axons from the developing mantle layer and will form the white matter UBERON:0004063 spinal cord alar plate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004063 alar column spinal cord|spinal cord alar column|spinal cord alar lamina The region of the mantle layer of the neural tube that lies dorsal to the sulcus limitans and contains primarily sensory neurons and interneurons involved in communication of sensory impulses; the alar plate develops into the dorsal horn in the grey matter of the spinal cord UBERON:0004060 neural tube ventricular layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004060 neural tube ventricular zone|neural tube ventricular germinal zone|neural tube ependymal layer|neural tube ependymal zone|ependymal layer The layer of undifferentiated, proliferating cells that line the neural tube lumen that is the immediate transformation of the germinal neuroepithelium UBERON:0004061 neural tube mantle layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004061 neural tube intermediate zone|future brain marginal layer The layer of glia and differentiating neurons that forms as a second layer around the germinal neuroepithium; as this develops it comes to lie between the ventricular and marginal layers and includes the basal and alar plates. Develops into neurons and glia forming a gray matter layer. CHEBI:18435 (+)-7-isojasmonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18435 NCBITaxon:6243 Rhabditidae organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_6243 CHEBI:18430 3-hydroxy-16-methoxy-2,3-dihydrotabersonine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18430 CHEBI:18431 7alpha,26-dihydroxycholesterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18431 UBERON:0004068 medial nasal prominence biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004068 medial nasal swelling|medial nasal process|prominentia nasalis medialis|nasomedial prominence|medial-nasal process The central area of the two limbs of a horseshoe-shaped mesenchymal swelling that lie medial to the olfactory placode or pit in the future nasal region of the embryo; it joins with the ipsilateral maxillary prominence in the formation of half of the upper jaw, and the nasal tip and philtrum of the upper lip develop from it UBERON:0018692 dorsal side of post-anal tail biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018692 UBERON:0018691 ventral side of post-anal tail biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018691 CHEBI:5810 hydroxymethylphosphonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_5810 UBERON:0004053 external male genitalia biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004053 male external genitalia|external male genital organ|organa genitalia masculina externa The external masculine genital organs, including the penis and scrotum CHEBI:18429 dehydrovomifoliol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18429 UBERON:0004054 internal male genitalia biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004054 organa genitalia masculina interna|male internal genitalia|internal male genital organ The internal masculine genital organs, including the testes, epididymides, deferent ducts, seminal vesicles, prostate, ejaculatory ducts, and bulbourethral glands CHEBI:18427 1D-1-O-methyl-myo-inositol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18427 CHEBI:18425 2-C-methyl-D-erythritol 2,4-cyclic diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18425 CHEBI:18426 1D-myo-inositol 1,2-cyclic phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18426 CHEBI:18421 superoxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18421 CHEBI:18422 sulfur dioxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18422 CHEBI:18420 magnesium(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18420 UBERON:0004058 biliary ductule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004058 cholangiole|biliary ductule|terminal cholangiole|bile ductule|bile capillary|biliary ductule|ductuli biliferi One of the fine terminal elements of the bile duct system, leaving the portal canal, and pursuing a course at the periphery of a lobule of the liver[BTO]. the excretory ducts of the liver that connect the interlobular ductules to the right or left hepatic duct[MP] GO:0044805 late nucleophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044805 LN A type of nucleophagy, distinct from piecemeal microautophagy of the nucleus (PNM) where the nuclear material is delivered to the vacuole/lysosome for breakdown and recycling later than observed for PNM. GO:0044806 G-quadruplex DNA unwinding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044806 The process by which G-quadruplex (also known as G4) DNA, which is a four-stranded DNA structure held together by guanine base pairing, is unwound or 'melted'. GO:0044803 multi-organism membrane organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044803 A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane, involving more than one organism. UBERON:0004042 spleen secondary B follicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004042 secondary spleen B cell follicle|splenic secondary B cell follicle The nodules of antigen-activated, differentiating B cells, follicular dendritic cells, antigen-presenting T cells and macrophages in the spleen white pulp GO:0044804 autophagy of nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044804 nucleophagy|nucleus degradation A form of autophagy, by which damaged or non-essential parts of the nucleus, or even an entire nucleus is degraded. UBERON:0004040 cortical intermediate zone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004040 cerebral cortex mantle layer|cortical mantle layer|IZ|cerebral cortex mantle zone The region of the developing mammalian cortex that extends between the ventricular zone and the cortical plate (CP); normally, the IZ is a region of tangential migration of cells, and at midgestation, the lower part of the IZ develops into the subventricular zone GO:0044801 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044801 GO:0044802 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044802 UBERON:0004041 spleen primary B follicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004041 primary spleen B cell follicle The nodules of small undifferentiated B lymphocytes and follicular dendritic cells located in the spleen white pulp GO:0044800 multi-organism membrane fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044800 The membrane organization process that joins two lipid bilayers to form a single membrane, involving more than one organism. GO:0044809 chemokine (C-C motif) ligand 17 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044809 thymus and activation regulated chemokine production|CCL17 production|TARC production The appearance of chemokine (C-C motif) ligand 17 (CCL17) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0044807 macrophage migration inhibitory factor production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044807 MIF production The appearance of macrophage migration inhibitory factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. CHEBI:18450 (R)-mandelonitrile biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18450 GO:0044808 oncostatin M production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044808 Oncostatin M production|OSM production The appearance of oncostatin M due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. UBERON:0018674 heart vasculature biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018674 cardiac vasculature An interconnected tubular multi-tissue structure that contains fluid that is actively transported around the heart. UBERON:0018673 neck of fibula biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018673 fibular neck|fibula neck UBERON:0018679 thoracic splanchnic nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018679 Thoracic splanchnic nerves are splanchnic nerves that arise from the sympathetic trunk in the thorax and travel inferiorly to provide sympathetic innervation to the abdomen. The nerves contain preganglionic sympathetic and general visceral afferent fibers. GO:0044816 Nsk1-Dlc1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044816 A dimer of Nsk1 (nucleolus spindle kinetochore 1) and the dynein light chain, Dlc1. The dimers form an oligomeric chain structure. Functions in the regulation of kinetochore-microtubule interactions and chromosome segregation. GO:0044817 hydrogen generation via biophotolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044817 hydrogen biosynthesis via biophotolysis The production of hydrogen which results from the dissociation by light of water into molecular hydrogen and oxygen. This process is observed in cyanobacteria and microalgae. GO:0044814 glycolytic fermentation via PFL pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044814 The glycolytic fermentation beginning with the anaerobic conversion of glucose to pyruvate by the glycolytic pathway, followed by pyruvate:formate lyase (PFL) activity. This pathway is found in facultative anaerobes such as E. coli. GO:0044815 DNA packaging complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044815 A protein complex that plays a role in the process of DNA packaging. GO:0044812 fermentative hydrogen production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044812 Wikipedia:Fermentative_hydrogen_production carbohydrate fermentation The fermentation of organic substances with a net release of hydrogen. GO:0044813 glycolytic fermentation via PFOR pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044813 The glycolytic fermentation beginning with the anaerobic conversion of glucose to pyruvate by the glycolytic pathway, continuing with pyruvate:ferredoxin oxidoreductase (PFOR) activity. This pathway is found in strict anaerobes such as Clostridia species. GO:0044810 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044810 GO:0044811 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044811 NCBITaxon:6231 Nematoda organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_6231 Nemata|roundworms|nematodes|nematodes|nematode|roundworm UBERON:0004035 cortical subplate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004035 subplate|subplate zone|SP|cerebral cortex subplate The transient outer neural tube region that contains the first generated post-mitotic neurons that receive synaptic input from thalamic axons and in turn project axons to the developing cortical plate GO:0044818 mitotic G2/M transition checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044818 A cell cycle checkpoint that detects and negatively regulates progression from G2 to M phase as part of a mitotic cell cycle. GO:0044819 mitotic G1/S transition checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044819 A cell cycle checkpoint that detects and negatively regulates progression from G1 to S phase as part of a mitotic cell cycle. GO:0005219 ryanodine-sensitive calcium-release channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005219 Reactome:R-HSA-2855020 ryanodine receptor|caffeine-sensitive calcium-release channel Enables the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts. GO:0005217 intracellular ligand-gated ion channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005217 Enables the transmembrane transfer of an ion by a channel that opens when a specific intracellular ligand has been bound by the channel complex or one of its constituent parts. GO:0005218 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005218 GO:0005215 transporter activity biolink:MolecularActivity go-plus goslim_flybase_ribbon|goslim_chembl|goslim_mouse|goslim_candida|goslim_agr|gocheck_do_not_annotate|goslim_plant|goslim_pir|goslim_metagenomics|goslim_aspergillus http://purl.obolibrary.org/obo/GO_0005215 EC:7.-.-.-|Reactome:R-HSA-178215|Reactome:R-HSA-168313 carrier Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells. GO:0005216 ion channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005216 Enables the facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. May be either selective (it enables passage of a specific ion only) or non-selective (it enables passage of two or more ions of same charge but different size). GO:0005213 structural constituent of egg chorion biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005213 structural protein of chorion|structural constituent of chorion The action of a molecule that contributes to the structural integrity of an egg chorion. An example of this is found in Drosophila melanogaster. GO:0005214 structural constituent of chitin-based cuticle biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005214 The action of a molecule that contributes to the structural integrity of a chitin-based cuticle. An example of this is found in Drosophila melanogaster. CHEBI:125678 N-acetyldopamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_125678 GO:0005211 obsolete plasma glycoprotein biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005211 plasma glycoprotein OBSOLETE. (Was not defined before being made obsolete). GO:0005212 structural constituent of eye lens biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005212 The action of a molecule that contributes to the structural integrity of the lens of an eye. GO:0019858 cytosine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019858 cytosine metabolism The chemical reactions and pathways involving cytosine, 4-amino-2-hydroxypyrimidine, a pyrimidine derivative that is one of the five main bases found in nucleic acids; it occurs widely in cytidine derivatives. GO:0019859 thymine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019859 thymine metabolism The chemical reactions and pathways involving thymine, 5-methyluracil, one of the two major pyrimidine bases present (as thymidine) in DNA but not found in RNA other than (as ribothymidine) in transfer RNA, where it is a minor base. GO:0019856 pyrimidine nucleobase biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019856 pyrimidine base synthesis|pyrimidine base formation|pyrimidine base biosynthesis|pyrimidine base anabolism|pyrimidine base biosynthetic process The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases. GO:0019857 5-methylcytosine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019857 5-methylcytosine metabolism The chemical reactions and pathways involving 5-methylcytosine, a methylated base of DNA. GO:0019854 L-ascorbic acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019854 MetaCyc:PWY0-301 ascorbate catabolism|ascorbate catabolic process|L-ascorbic acid catabolism|L-ascorbic acid degradation|vitamin C catabolism|L-ascorbic acid breakdown|vitamin C catabolic process The chemical reactions and pathways resulting in the breakdown of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, which is required as a cofactor in the oxidation of prolyl residues to hydroxyprolyl, and other reactions. GO:0019855 calcium channel inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019855 Stops, prevents, or reduces the activity of a calcium channel. GO:0019852 L-ascorbic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019852 ascorbate metabolic process|ascorbate metabolism|vitamin C metabolic process|L-ascorbic acid metabolism|vitamin C metabolism The chemical reactions and pathways involving L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species. GO:0019853 L-ascorbic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019853 MetaCyc:PWY-882 L-ascorbic acid anabolism|ascorbate biosynthetic process|ascorbate biosynthesis|L-ascorbic acid synthesis|L-ascorbic acid formation|L-ascorbic acid biosynthesis|vitamin C biosynthetic process|vitamin C biosynthesis The chemical reactions and pathways resulting in the formation of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, which is required as a cofactor in the oxidation of prolyl residues to hydroxyprolyl, and other reactions. GO:0019850 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019850 GO:0019851 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019851 GO:0005228 intracellular sodium activated potassium channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005228 Enables the transmembrane transfer of potassium by a channel that opens in response to stimulus by a sodium ion or ions. Transport by a channel involves facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism. Sodium activated potassium channels have distinctive properties, including a large single channel conductance, subconductance states, and a block of single channel currents at positive potentials, similar to inward rectification. GO:0005229 intracellular calcium activated chloride channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005229 Reactome:R-HSA-2684901|Reactome:R-HSA-2744242|Reactome:R-HSA-9659568|Reactome:R-HSA-2744361 Enables the transmembrane transfer of chloride by a channel that opens in response to stimulus by a calcium ion or ions. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism. GO:0005226 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005226 GO:0005227 calcium activated cation channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005227 polycystin|intracellular calcium-activated potassium channel Enables the calcium concentration-regulatable energy-independent passage of cations across a lipid bilayer down a concentration gradient. GO:0005224 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005224 GO:0005225 volume-sensitive anion channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005225 Reactome:R-HSA-8941543 volume-regulated channel Enables the transmembrane transfer of an anion by a volume-sensitive channel. An anion is a negatively charged ion. A volume-sensitive channel is a channel that responds to changes in the volume of a cell. GO:0005222 intracellular cAMP-activated cation channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005222 hyperpolarization-activated cyclic nucleotide-gated channel activity|intracellular 3',5'-cAMP activated cation channel activity|intracellular adenosine 3',5'-cyclophosphate activated cation channel activity|intracellular cAMP activated cation channel activity|intracellular cyclic AMP activated cation channel activity|intracellular 3',5' cAMP activated cation channel activity|HCN channel activity Enables the transmembrane transfer of a cation by a channel that opens when intracellular cAMP has been bound by the channel complex or one of its constituent parts. GO:0005223 intracellular cGMP-activated cation channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005223 intracellular cGMP activated cation channel activity Enables the transmembrane transfer of a cation by a channel that opens when intracellular cGMP has been bound by the channel complex or one of its constituent parts. GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005220 inositol-1,4,5-trisphosphate receptor activity|IP3 receptor activity|InsP3 receptor Enables the transmembrane transfer of a calcium ion by a channel that opens when inositol 1,4,5-trisphosphate (IP3) has been bound by the channel complex or one of its constituent parts. GO:0005221 intracellular cyclic nucleotide activated cation channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005221 Reactome:R-HSA-2514867 Enables the transmembrane transfer of a cation by a channel that opens when intracellular cyclic nucleotide has been bound by the channel complex or one of its constituent parts. GO:0019869 chloride channel inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019869 Stops, prevents, or reduces the activity of a chloride channel. GO:0019867 outer membrane biolink:CellularComponent go-plus goslim_metagenomics http://purl.obolibrary.org/obo/GO_0019867 The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites. GO:0019868 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019868 GO:0019865 immunoglobulin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019865 Interacting selectively and non-covalently with an immunoglobulin. GO:0019866 organelle inner membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019866 The inner, i.e. lumen-facing, lipid bilayer of an organelle envelope; usually highly selective to most ions and metabolites. GO:0019863 IgE binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019863 Interacting selectively and non-covalently with an immunoglobulin of the IgE isotype. GO:0019864 IgG binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0019864 Interacting selectively and non-covalently with an immunoglobulin of an IgG isotype. GO:0019861 obsolete flagellum biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019861 Wikipedia:Flagellum flagellum OBSOLETE. Long whiplike or feathery structures borne either singly or in groups by the motile cells of many bacteria and unicellular eukaryotes and by the motile male gametes of many eukaryotic organisms, which propel the cell through a liquid medium. GO:0019862 IgA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019862 Interacting selectively and non-covalently with an immunoglobulin of an IgA isotype. GO:0019860 uracil metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019860 uracil metabolism The chemical reactions and pathways involving uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA. GO:0019838 growth factor binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0019838 neurotrophin TRK receptor activity Interacting selectively and non-covalently with any growth factor, proteins or polypeptides that stimulate a cell or organism to grow or proliferate. GO:0019839 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019839 GO:0019836 hemolysis by symbiont of host erythrocytes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019836 regulation of cytolysis of host cells by symbiont|haemolysis in host|hemolysis by symbiont of host RBCs|hemolysis by symbiont of host red blood cells|hemolysin activity The cytolytic destruction of red blood cells, with the release of intracellular hemoglobin, in the host organism by a symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0019837 obsolete herbicide susceptibility/resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019837 herbicide susceptibility/resistance OBSOLETE. (Was not defined before being made obsolete). GO:0019834 phospholipase A2 inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019834 Stops, prevents or reduces the activity of the enzyme phospholipase A2. GO:0019835 cytolysis biolink:BiologicalProcess go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0019835 Wikipedia:Cytolysis necrosis|autolysin activity|bacteriolytic toxin activity|bacteriocin activity|lysis|holin|lysin activity The rupture of cell membranes and the loss of cytoplasm. GO:0019832 obsolete mercuric sensitivity/resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019832 mercuric sensitivity/resistance OBSOLETE. (Was not defined before being made obsolete). GO:0019833 obsolete ice nucleation activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019833 ice nucleation activity OBSOLETE. Catalysis of the formation of ice crystals in extracellular fluid at relatively high temperatures (up to -2 degrees C) to protect the organism from damage by intracellular ice formation. Ice nucleation proteins function by binding an ice crystal and then encouraging it to form larger crystals. Ice nucleation is a chemical process but these proteins can positively regulate it. There are two different uses of ice nucleation proteins: bacteria secrete them extracellularly to cause a host organism's cells to freeze and die, and fish use them to protect themselves from intracellular ice formation. GO:0019830 obsolete cadmium sensitivity/resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019830 cadmium sensitivity/resistance OBSOLETE. (Was not defined before being made obsolete). GO:0019831 obsolete chromate sensitivity/resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019831 chromate sensitivity/resistance OBSOLETE. (Was not defined before being made obsolete). GO:0005208 obsolete amyloid protein biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005208 amyloid protein OBSOLETE. (Was not defined before being made obsolete). GO:0005209 obsolete plasma protein biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005209 plasma protein OBSOLETE. (Was not defined before being made obsolete). GO:0005206 obsolete heparin sulfate proteoglycan biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005206 heparin sulfate proteoglycan|heparin sulphate proteoglycan OBSOLETE. (Was not defined before being made obsolete). GO:0005207 obsolete extracellular matrix glycoprotein biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005207 extracellular matrix glycoprotein OBSOLETE. (Was not defined before being made obsolete). GO:0005204 obsolete chondroitin sulfate proteoglycan biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005204 chondroitin sulphate proteoglycan|chondroitin sulfate proteoglycan OBSOLETE. (Was not defined before being made obsolete). GO:0005205 obsolete chondroitin sulfate/dermatan sulfate proteoglycan biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005205 chondroitin sulfate/dermatan sulfate proteoglycan|chondroitin sulphate/dermatan sulphate proteoglycan OBSOLETE. (Was not defined before being made obsolete). GO:0005202 obsolete collagen biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005202 collagen OBSOLETE. (Was not defined before being made obsolete). GO:0005203 obsolete proteoglycan biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005203 proteoglycan OBSOLETE. (Was not defined before being made obsolete). GO:0005200 structural constituent of cytoskeleton biolink:MolecularActivity go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0005200 The action of a molecule that contributes to the structural integrity of a cytoskeletal structure. GO:0005201 extracellular matrix structural constituent biolink:MolecularActivity go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0005201 extracellular matrix glycoprotein|core matrisome|core extracellular matrix The action of a molecule that contributes to the structural integrity of the extracellular matrix. GO:0019849 obsolete cytotoxin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019849 cytotoxin activity OBSOLETE. Acts as to cause injury to other living cells. GO:0019847 obsolete neurotoxin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019847 neurotoxin activity OBSOLETE. Acts to inhibit neural function in another living organism. GO:0019848 obsolete conotoxin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019848 conotoxin activity OBSOLETE. Acts to inhibit neural function in another organism by inhibiting voltage-gated calcium ion channels and neurotransmitter release. This function is thought to be specific to the venom of two marine snail species. GO:0019845 obsolete exotoxin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019845 exotoxin activity OBSOLETE. The function of a toxin formed by a microorganism and secreted into the surrounding medium. GO:0019846 obsolete enterotoxin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019846 enterotoxin activity OBSOLETE. Acts as to cause injury to the intestinal mucosa of other living organisms. GO:0019843 rRNA binding biolink:MolecularActivity go-plus goslim_generic|goslim_chembl|goslim_yeast http://purl.obolibrary.org/obo/GO_0019843 base pairing with rRNA Interacting selectively and non-covalently with ribosomal RNA. GO:0019844 obsolete endotoxin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019844 endotoxin activity OBSOLETE. The function of any microbial toxin that cannot be easily separated from the structure of the cell. GO:0019841 retinol binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019841 vitamin A1 alcohol binding|vitamin A1 binding Interacting selectively and non-covalently with retinol, vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A. Retinol is an intermediate in the vision cycle and it also plays a role in growth and differentiation. GO:0019842 vitamin binding biolink:MolecularActivity go-plus goslim_pir|goslim_metagenomics http://purl.obolibrary.org/obo/GO_0019842 Interacting selectively and non-covalently with a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. GO:0019840 isoprenoid binding biolink:MolecularActivity go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0019840 Interacting selectively and non-covalently with any isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues. GO:0019818 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019818 GO:0019819 P1 peroxisome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019819 peroxisome vesicle A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P1 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content; they contain fewer peroxisomal proteins than the other subforms. GO:0019816 obsolete B cell receptor accessory molecule complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019816 B cell receptor accessory molecule complex OBSOLETE. (Was not defined before being made obsolete). GO:0019817 vesicle fusion with peroxisome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019817 The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the peroxisome. GO:0019814 immunoglobulin complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0019814 antibody A protein complex that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains, held together by disulfide bonds and sometimes complexed with additional proteins. An immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. GO:0019815 B cell receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019815 immunoglobulin complex, membrane bound|B lymphocyte receptor complex|B cell receptor accessory molecule complex|B-lymphocyte receptor complex|BCR complex|B-cell receptor complex|antibody An immunoglobulin complex that is present in the plasma membrane of B cells and that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins. GO:0019812 type I site-specific deoxyribonuclease complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019812 type I restriction enzyme complex A multisubunit complex composed of two copies of a restriction (R) subunit, two copies of a methylation (M) subunit, and one copy of a specificity (S) subunit. This complex recognizes specific short DNA sequences (through the S subunit), and binds to them. If the recognition site is hemimethylated, the complex acts as a methyltransferase which modifies the recognition site, using S-adenosylmethionine as the methyl donor. Only the M and S subunits are required for this reaction. If the complex binds to an unmethylated recognition site, then the complex translocates the DNA bidirectionally in an ATP-dependent manner. When the translocation is stalled by impact with another complex or unusual DNA structure, the enzyme functions as an endonuclease and cleavage of the DNA will occur, hundreds or thousands of base pairs away from the recognition site. These DNA restriction systems are used by bacteria to defend against phage and other foreign DNA that may enter a cell. GO:0019813 type III site-specific deoxyribonuclease complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019813 type III restriction enzyme complex A heterodimeric enzyme complex composed of two subunits, Res and Mod, that functions as an endonuclease and cleaves DNA. Cleavage will only occur when there are two un-methylated copies of a specific recognition site in an inverse orientation on the DNA. Cleavage occurs at a specific distance away from one of the recognition sites. The Mod subunit can act alone as a methyltansferase. DNA restriction systems such as this are used by bacteria to defend against phage and other foreign DNA that may enter a cell. GO:0019810 putrescine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019810 Interacting selectively and non-covalently with putrescine, 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine. GO:0019811 cocaine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019811 Interacting selectively and non-covalently with cocaine (2-beta-carbomethoxy-3-beta-benzoxytropane), an alkaloid obtained from dried leaves of the South American shrub Erythroxylon coca or by chemical synthesis. CHEBI:43474 hydrogenphosphate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_43474 GO:0019829 ATPase-coupled cation transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019829 Reactome:R-HSA-5251989|Reactome:R-HSA-5692480 ATP-dependent cation transmembrane transporter activity|plasma membrane cation-transporting ATPase|cation ABC transporter|cation-transporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cation(out) = ADP + phosphate + cation(in). GO:0019827 stem cell population maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019827 maintenance of pluripotency The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types. GO:0019828 aspartic-type endopeptidase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019828 aspartic protease inhibitor activity Stops, prevents or reduces the activity of aspartic-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; the optimum reaction pH is below 5 due to an aspartic residue involved in the catalytic process. GO:0019825 oxygen binding biolink:MolecularActivity go-plus goslim_plant|goslim_pir http://purl.obolibrary.org/obo/GO_0019825 cytochrome P450|cytochrome P450 activity Interacting selectively and non-covalently with oxygen (O2). GO:0019826 oxygen sensor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019826 Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of oxygen (O2). GO:0019823 P5 peroxisome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019823 peroxisome vesicle A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P5 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content. GO:0019824 P6 peroxisome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019824 peroxisome vesicle A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P6 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content, and are equivalent to mature peroxisomes. GO:0019821 P3 peroxisome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019821 peroxisome vesicle A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P3 peroxisomes are formed by fusion of P1 and P2 peroxisomes, and are distinguished from the other subforms on the bases of buoyant density and protein content. GO:0019822 P4 peroxisome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019822 peroxisome vesicle A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P4 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content. GO:0019820 P2 peroxisome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019820 peroxisome vesicle A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P2 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content; they are the least dense of the subforms observed. CHEBI:43468 (2R,3S)-3-isopropylmalic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_43468 CHEBI:111006 maltose 6'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_111006 GO:0019809 spermidine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019809 Interacting selectively and non-covalently with spermidine, N-(3-aminopropyl)-1,4-diaminobutane. GO:0019807 aspartoacylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019807 MetaCyc:ASPARTOACYLASE-RXN|Reactome:R-HSA-5691507|EC:3.5.1.15|RHEA:10872 N-acetylaspartate amidohydrolase activity|acetyl-aspartic deaminase activity|acylase II|N-acyl-L-aspartate amidohydrolase activity|aminoacylase II activity Catalysis of the reaction: N-acyl-L-aspartate + H2O = a fatty acid anion + L-aspartate. CHEBI:43451 hydrogen iodide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_43451 GO:0019808 polyamine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019808 Interacting selectively and non-covalently with polyamines, organic compounds containing two or more amino groups. GO:0019805 quinolinate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019805 quinolinate biosynthesis|quinolinate anabolism|quinolinate synthesis|quinolinate formation The chemical reactions and pathways resulting in the formation of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid. GO:0019806 bromide peroxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019806 EC:1.11.1.18 bromoperoxidase activity Catalysis of the reaction: 2 R-H + 2 bromide + hydrogen peroxide = 2 R-Br + 2 H2O. Enzymes with this activity often accept other halide ions as substrates, including chloride and iodide. GO:0019803 peptidyl-aspartic acid carboxylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019803 RESID:AA0304 The carboxylation of peptidyl-aspartic acid to form peptidyl-L-beta-carboxyaspartic acid. GO:0019804 obsolete quinolinate synthetase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019804 quinolinate synthetase complex OBSOLETE. A heterodimer which acts as a quinolinate synthetase; quinolinate synthetase B (L-aspartate oxidase) catalyzes the oxidation of L-aspartate to L-iminoaspartate; quinolinate synthetase A condenses L-imidoaspartate and dihydroxyacetone to quinolinate. GO:0019801 cyclization of asparagine involved in intein-mediated protein splicing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019801 RESID:AA0302 cyclization of asparagine, during protein splicing The cyclization of asparagine to yield an L-aspartimide (otherwise known as alpha-aminosuccinimide) residue at the C-terminus of an excised intein during protein splicing. GO:0019802 cyclization of glutamine involved in intein-mediated protein splicing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019802 RESID:AA0303 cyclization of glutamine, during protein splicing The cyclization of glutamine to yield an L-glutamimide residue at the C-terminus of an excised intein during protein splicing. GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019800 RESID:AA0219 peptide cross-linking via chondroitin 4-sulphate glycosaminoglycan The formation of a cross-link between peptide chains mediated by a chondroitin 4-sulfate glycosaminoglycan that originates from a typical O-glycosidic link to serine of one chain; the other chain is esterified, via the alpha-carbon of its C-terminal Asp, to C-6 of an internal N-acetylgalactosamine of the glycosaminoglycan chain. CHEBI:5870 imidacloprid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_5870 GO:0030378 serine racemase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030378 RHEA:10980|MetaCyc:5.1.1.18-RXN|Reactome:R-HSA-9014766|EC:5.1.1.18 Catalysis of the synthesis of free D-serine from L-serine. GO:0030379 neurotensin receptor activity, non-G protein-coupled biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030379 non-G-protein coupled neurotensin receptor activity|neurotensin receptor activity, non-G-protein coupled|non G protein coupled neurotensin receptor activity|neurotensin receptor activity, non G protein coupled|non-G-protein-coupled neurotensin receptor activity Combining with neurotensin, a neuropeptide active in the central and peripheral nervous system in mammals, and transmitting the signal from one side of the membrane to the other by a mechanism independent of coupling to G proteins. GO:0030376 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030376 GO:0030377 urokinase plasminogen activator receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030377 Wikipedia:Urokinase_receptor urokinase plasminogen activator receptor|uPAR|U-plasminogen activator receptor activity Combining with the urokinase plasminogen activator to initiate a change in cell activity. GO:0030374 nuclear receptor coactivator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030374 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding|ligand-dependent nuclear receptor transcription co-activator activity|ligand-activated RNA polymerase II transcription factor binding transcription factor activity|nuclear receptor transcription coactivator activity|ligand-dependent nuclear receptor transcription coactivator activity A transcription coactivator activity that activates or increases the transcription of specific gene sets via binding to a DNA-bound nuclear receptor, either on its own or as part of a complex. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators. A fourth class of coactivator activity is the bridging of a DNA-binding transcription factor to the general (basal) transcription machinery. The Mediator complex, which bridges sequence-specific DNA binding transcription factors and RNA polymerase, is also a transcription coactivator. GO:0030375 obsolete thyroid hormone receptor coactivator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030375 thyroid hormone receptor activator activity|thyroid hormone receptor co-activator activity OBSOLETE. The function of a transcription cofactor that activates transcription in conjunction with a thyroid hormone-dependent nuclear receptor from a RNA polymerase II promoter; does not bind DNA itself. GO:0030372 high molecular weight B cell growth factor receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030372 high molecular weight B lymphocyte growth factor receptor binding|high molecular weight B cell growth factor receptor ligand|high molecular weight B-lymphocyte growth factor receptor binding|high molecular weight B-cell growth factor receptor binding Interacting selectively and non-covalently with the high molecular weight B cell growth factor receptor. GO:0030373 high molecular weight B cell growth factor receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030373 HMW-BCGF receptor|high molecular weight B-cell growth factor receptor activity|high molecular weight B-lymphocyte growth factor receptor activity|high molecular weight B lymphocyte growth factor receptor activity Combining with a high molecular weight B cell growth factor and transmitting the signal to initiate a change in cell activity. CHEBI:5686 heterocyclic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_5686 GO:0030370 intercellular adhesion molecule-3 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030370 ICAM-3 receptor ligand|ICAM-3 receptor binding|intercellular adhesion molecule-3 receptor ligand Interacting selectively and non-covalently with receptors for intercellular adhesion molecule-3 (ICAM-3), such as DC-SIGN and LFA-1. GO:0030371 translation repressor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030371 Antagonizes ribosome-mediated translation of mRNA into a polypeptide. GO:0030369 ICAM-3 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030369 Combining with ICAM-3, intercellular adhesion molecule 3, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. ICAM-3, or CD50, are constitutively expressed on monocytes, granulocytes and lymphocytes; on physiological stimulation, they become transiently phosphorylated on serine residues. GO:0030367 interleukin-17 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030367 interleukin-17 receptor ligand|IL-17 Interacting selectively and non-covalently with the interleukin-17 receptor. GO:0030368 interleukin-17 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030368 Wikipedia:Interleukin-17_receptor IL-17 receptor activity|IL-17R Combining with any member of the interleukin-17 family of cytokines and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0030365 obsolete cleavage stimulation factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030365 cleavage stimulation factor activity|CstF OBSOLETE. A factor is necessary for cleavage but not for poly(A) addition in mRNA 3' end processing; can stimulate poly(A) addition on substrates with a CstF binding site upstream of the AAUAAA hexanucleotide. GO:0030366 molybdopterin synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030366 Reactome:R-HSA-947541|EC:2.8.1.12|RHEA:26333 Catalysis of the conversion of precursor Z to molybdopterin, the final step in molybdopterin biosynthesis. GO:0030363 obsolete pre-mRNA cleavage factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030363 pre-mRNA cleavage factor activity OBSOLETE. Any activity required for the process of mRNA cleavage. GO:0030364 obsolete cleavage and polyadenylylation specificity factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030364 cleavage and polyadenylylation specificity factor activity|cleavage and polyadenylation specificity factor activity|cleavage/polyadenylation specificity factor activity|CPSF OBSOLETE. A factor required in mRNA 3' end processing for both the cleavage and poly(A) addition reactions and, consistent with this function, recognizes AAUAAA, a signal also essential for both reactions. GO:0030361 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030361 GO:0030362 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030362 CHEBI:5697 palmitoyl-[acyl-carrier protein] biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_5697 GO:0030360 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030360 GO:0030358 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030358 GO:0030359 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030359 GO:0030356 obsolete small cytoplasmic ribonucleoprotein biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030356 scRNP|small cytoplasmic ribonucleoprotein OBSOLETE. (Was not defined before being made obsolete). GO:0030357 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030357 GO:0005396 obsolete transmembrane conductance regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005396 transmembrane conductance regulator activity OBSOLETE. (Was not defined before being made obsolete). GO:0005395 obsolete eye pigment precursor transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005395 OBSOLETE. Catalysis of the reaction: ATP + H2O + eye pigment precursor(in) = ADP + phosphate + eye pigment precursor(out). GO:0030354 melanin-concentrating hormone activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030354 The action characteristic of melanin-concentrating hormone, a cyclic peptide hormone that, upon receptor binding, induces melanin aggregation in melanocytes, and is also involved in regulating food intake and energy balance in mammals. GO:0030355 obsolete small nucleolar ribonucleoprotein biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030355 small nucleolar ribonucleoprotein|snoRNP OBSOLETE. (Was not defined before being made obsolete). GO:0030352 inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030352 Catalysis of the reaction: inositol-1,4,5,6-tetrakisphosphate + H2O = inositol-1,4,5-trisphosphate + phosphate. GO:0030353 fibroblast growth factor receptor antagonist activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030353 FGF receptor antagonist activity|FGFR antagonist activity Interacts with the fibroblast growth factor receptor to reduce the action of another ligand, the agonist. GO:0030350 iron-responsive element binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030350 IRE binding Interacting selectively and non-covalently with the iron-responsive element, a regulatory sequence found in the 5'- and 3'-untranslated regions of mRNAs encoding many iron-binding proteins. GO:0030351 inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030351 Reactome:R-HSA-1855163 Catalysis of the reaction: inositol-1,3,4,5,6-pentakisphosphate + H2O = inositol-1,4,5,6-tetrakisphosphate + phosphate. GO:0030349 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030349 RO:0002380 branching_part_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002380 RO:0002380 GO:0030347 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030347 GO:0030348 syntaxin-3 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030348 Interacting selectively and non-covalently with the SNAP receptor syntaxin-3. GO:0030345 structural constituent of tooth enamel biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030345 The action of a molecule that contributes to the structural integrity of tooth enamel. GO:0030346 protein phosphatase 2B binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030346 protein phosphatase 3 binding|calcineurin binding Interacting selectively and non-covalently with the enzyme protein phosphatase 2B. RO:0002385 has potential to developmentally contribute to biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002385 RO:0002385 x has potential to developmentrally contribute to y iff x developmentally contributes to y or x is capable of developmentally contributing to y RO:0002387 has potential to develop into biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002387 RO:0002387 x has the potential to develop into y iff x develops into y or if x is capable of developing into y RO:0002388 has potential to directly develop into biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002388 RO:0002388 x has potential to directly develop into y iff x directly develops into y or x is capable of directly developing into y RO:0002384 has developmental potential involving biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002384 RO:0002384 x has developmental potential involving y iff x is capable of a developmental process with output y. y may be the successor of x, or may be a different structure in the vicinity (as for example in the case of developmental induction). GO:0030343 vitamin D3 25-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030343 MetaCyc:RXN-9829|Reactome:R-HSA-209845|RHEA:32903|Reactome:R-HSA-5602147 cholecalciferol 25-hydroxylase activity Catalysis of the reaction: vitamin D3 + NADPH + H+ + O2 = calcidiol + NADP+ + H2O. GO:0030344 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030344 GO:0030341 chondroitin AC lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030341 MetaCyc:4.2.2.5-RXN|EC:4.2.2.5 chondroitinase activity|chondroitin AC eliminase activity|chondroitin lyase activity|chondroitinase AC|chondroitin sulfate lyase activity|ChnAC Catalysis of the eliminative degradation of polysaccharides containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucuronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups. GO:0030342 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030342 Reactome:R-HSA-209765|Reactome:R-HSA-5602004|Reactome:R-HSA-211950 1,25-(OH)2D3 24-hydroxylase activity|calcitriol 24-hydroxylase activity Catalysis of the hydroxylation of C-24 of 1-alpha,25-hydroxycholecalciferol (25-hydroxyvitamin D3; calcitriol). GO:0030340 hyaluronate lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030340 MetaCyc:HYALURONATE-LYASE-RXN|RHEA:50240|EC:4.2.2.1 hyaluronidase [but cf. EC:3.2.1.35 (hyalurononglucosaminidase) and EC:3.2.1.36 (hyaluronoglucuronidase)]|spreading factor activity|hyaluronidase activity|glucuronoglycosaminoglycan lyase activity|mucinase activity Catalysis of the reaction: hyaluronate = n 3-(4-deoxy-beta-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine. CHEBI:5672 heptan-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_5672 GO:0030338 CMP-N-acetylneuraminate monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030338 MetaCyc:1.14.13.45-RXN|RHEA:16145|EC:1.14.18.2 cytidine-5'-monophosphate-N-acetylneuraminic acid hydroxylase activity|N-acetylneuraminic monooxygenase activity|CMP-Neu5Ac hydroxylase activity|cytidine monophosphoacetylneuraminate monooxygenase activity|CMP-N-acetylneuraminate hydroxylase activity|CMP-N-acetylneuraminic acid hydroxylase activity|CMP-N-acetylneuraminate,ferrocytochrome-b5:oxygen oxidoreductase (N-acetyl-hydroxylating) Catalysis of the reaction: CMP-N-acetylneuraminate + NADPH + H+ + O2 = CMP-N-glycoloylneuraminate + NADP+ + H2O. GO:0030339 fatty-acyl-ethyl-ester synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030339 EC:3.1.1.67|RHEA:16641|MetaCyc:FATTY-ACYL-ETHYL-ESTER-SYNTHASE-RXN FAEES activity|fatty-acyl ethyl ester synthase|FAEE synthase activity|long-chain-fatty-acyl-ethyl-ester acylhydrolase activity Catalysis of the reaction: a long-chain-acyl ethyl ester + H2O = a long-chain carboxylic acid + ethanol. CHEBI:149689 D-dopa zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_149689 GO:0030336 negative regulation of cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030336 down-regulation of cell migration|downregulation of cell migration|down regulation of cell migration|inhibition of cell migration Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration. GO:0030337 DNA polymerase processivity factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030337 processivity clamp|sliding clamp An enzyme regulator activity that increases the processivity of polymerization by DNA polymerase, by allowing the polymerase to move rapidly along DNA while remaining topologically bound to it. GO:0005378 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005378 GO:0030334 regulation of cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030334 Any process that modulates the frequency, rate or extent of cell migration. GO:0030335 positive regulation of cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030335 activation of cell migration|up regulation of cell migration|upregulation of cell migration|stimulation of cell migration|up-regulation of cell migration Any process that activates or increases the frequency, rate or extent of cell migration. GO:0005379 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005379 GO:0005376 obsolete plasma membrane copper transporter biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005376 plasma membrane copper transporter OBSOLETE. (Was not defined before being made obsolete). RO:0002374 has_fused_element biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002374 RO:0002374 x has_fused_element y iff: there exists some z : x has_part z, z homologous_to y, and y is a distinct element, the boundary between x and z is largely fiat GO:0005377 obsolete intracellular copper ion transporter biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005377 intracellular copper transporter|intracellular copper ion transporter OBSOLETE. (Was not defined before being made obsolete). RO:0002376 tributary_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002376 RO:0002376 drains into GO:0005375 copper ion transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005375 Reactome:R-HSA-437300|RHEA:28703 plasma membrane copper transporter|intracellular copper ion transporter|copper uptake transmembrane transporter activity Enables the transfer of copper (Cu) ions from one side of a membrane to the other. GO:0005372 water transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005372 Enables the transfer of water (H2O) from one side of a membrane to the other. GO:0005373 obsolete heavy metal ion porter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005373 metal ion transporter|heavy metal ion porter activity OBSOLETE. A transporter of heavy metal ions that utilizes a carrier-mediated process to catalyze uniport, symport or antiport between aqueous phases on either side of a lipid membrane. RO:0002371 attaches_to biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002371 RO:0002371 GO:0005370 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005370 RO:0002372 has_muscle_origin biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002372 RO:0002372 m has_muscle_origin s iff m is attaches_to s, and it is the case that when m contracts, s does not move. The site of the origin tends to be more proximal and have greater mass than what the other end attaches to. GO:0005371 tricarboxylate secondary active transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005371 tricarboxylate carrier activity Enables the transfer of tricarboxylate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. PATO:0002505 nucleated biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PATO_0002505 A nucleate quality inhering in a bearer by virtue of the bearer's having one or more nucleus. RO:0002373 has_muscle_insertion biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002373 RO:0002373 m has_muscle_insertion s iff m is attaches_to s, and it is the case that when m contracts, s moves. Insertions are usually connections of muscle via tendon to bone. GO:0005380 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005380 NCBITaxon:1437180 Acrogymnospermae organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_1437180 CHEBI:149690 N-(fatty acyl)-L-phenylalanine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_149690 GO:0030332 cyclin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030332 Interacting selectively and non-covalently with cyclins, proteins whose levels in a cell varies markedly during the cell cycle, rising steadily until mitosis, then falling abruptly to zero. As cyclins reach a threshold level, they are thought to drive cells into G2 phase and thus to mitosis. GO:0030333 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030333 GO:0030330 DNA damage response, signal transduction by p53 class mediator biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030330 DNA damage response, activation of p53|p53-mediated DNA damage response|p53 signaling pathway|TP53 signaling pathway A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage. GO:0030331 estrogen receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030331 Interacting selectively and non-covalently with an estrogen receptor. GO:0030329 prenylcysteine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030329 prenylcysteine metabolism The chemical reactions and pathways involving prenylcysteine, 3-methyl-2-buten-1-yl-cysteine, a derivative of the amino acid cysteine formed by the covalent addition of a prenyl residue. GO:0030327 prenylated protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030327 prenylated protein catabolism|prenylated protein degradation|prenylated protein breakdown The chemical reactions and pathways resulting in the breakdown of prenylated proteins. GO:0030328 prenylcysteine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030328 prenylcysteine catabolism|prenylcysteine degradation|prenylcysteine breakdown The chemical reactions and pathways resulting in the breakdown of prenylcysteine, 3-methyl-2-buten-1-yl-cysteine, a derivative of the amino acid cysteine formed by the covalent addition of a prenyl residue. GO:0030325 adrenal gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030325 interrenal gland The process whose specific outcome is the progression of the adrenal gland over time, from its formation to the mature structure. This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells. GO:0030326 embryonic limb morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030326 The process, occurring in the embryo, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping. GO:0030323 respiratory tube development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030323 The process whose specific outcome is the progression of the respiratory tube over time, from its formation to the mature structure. The respiratory tube is assumed to mean any tube in the respiratory tract. GO:0030324 lung development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030324 The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax. GO:0005388 calcium transmembrane transporter activity, phosphorylative mechanism biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005388 MetaCyc:3.6.3.8-RXN|Reactome:R-HSA-418365|Reactome:R-HSA-427910|EC:7.2.2.10|Reactome:R-HSA-418309|Reactome:R-HSA-936883|RHEA:18105 sarco(endo)plasmic reticulum Ca2+-ATPase|calcium-transporting ATPase activity|calcium pump|Ca2+-transporting ATPase activity|calcium-translocating P-type ATPase activity|calcium transporting ATPase activity|ATP-dependent calcium transmembrane transporter activity|ATPase-coupled calcium transmembrane transporter activity|calcium efflux ATPase|Ca(2+)-transporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ca2+(cis) = ADP + phosphate + Ca2+(trans). GO:0005385 zinc ion transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005385 Reactome:R-HSA-5654125|Reactome:R-HSA-442422|Reactome:R-HSA-442345|Reactome:R-HSA-442387|Reactome:R-HSA-442405|Reactome:R-HSA-442393|Reactome:R-HSA-435366|Reactome:R-HSA-437084|Reactome:R-HSA-437085|Reactome:R-HSA-437129|Reactome:R-HSA-437139|RHEA:29351|Reactome:R-HSA-437136|Reactome:R-HSA-435375|Reactome:R-HSA-442317 zinc, iron permease activity|zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity|zinc, cadmium uptake permease activity|cobalt, zinc uptake permease activity Enables the transfer of zinc (Zn) ions from one side of a membrane to the other. GO:0005386 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005386 GO:0005384 manganese ion transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005384 RHEA:28699|Reactome:R-HSA-8959798 Enables the transfer of manganese (Mn) ions from one side of a membrane to the other. GO:0005381 iron ion transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005381 RHEA:29579|Reactome:R-HSA-904830|Reactome:R-HSA-917936|Reactome:R-HSA-435349|Reactome:R-HSA-5623558|Reactome:R-HSA-5655733 iron transporter activity|zinc, iron permease activity|multicopper ferroxidase iron transport mediator activity|transmembrane iron ion permease activity|iron channel activity|iron cation channel activity|transmembrane iron permease activity Enables the transfer of iron (Fe) ions from one side of a membrane to the other. CHEBI:149673 (1S,2R)-ephedrine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_149673 GO:0005382 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005382 GO:0005390 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005390 GO:0005391 P-type sodium:potassium-exchanging ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005391 MetaCyc:3.6.3.9-RXN|Reactome:R-HSA-936897|EC:7.2.2.13|Wikipedia:ATPase,_Na%2B/K%2B_transporting,_alpha_1|RHEA:18353 Na(+)/K(+)-ATPase activity|Na+/K+-ATPase activity|sodium/potassium-transporting ATPase activity|Na+,K+-ATPase activity|sodium:potassium-exchanging ATPase activity|Na,K-activated ATPase activity|Na(+)/K(+)-exchanging ATPase activity|Na+/K+-exchanging ATPase activity|P-type sodium:potassium-exchanging ATPase activity|sodium pump|sodium/potassium-exchanging ATPase activity|sodium:potassium exchanging ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) + K+(out) = ADP + phosphate + Na+(out) + K+(in). RO:0002356 results in specification of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002356 RO:0002356 The relationship linking a cell and its participation in a process that results in the fate of the cell being specified. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. GO:0030321 transepithelial chloride transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030321 The directed movement of chloride ions from one side of an epithelium to the other. GO:0030322 stabilization of membrane potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030322 The accomplishment of a non-fluctuating membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. GO:0030320 cellular monovalent inorganic anion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030320 Any process involved in the maintenance of an internal steady state of monovalent inorganic anions at the level of a cell. GO:0030318 melanocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030318 melanocyte cell differentiation|melanophore differentiation The process in which a relatively unspecialized cell acquires specialized features of a melanocyte. GO:0030319 obsolete cellular di-, tri-valent inorganic anion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030319 cellular di-, tri-valent inorganic anion homeostasis OBSOLETE. Any process involved in the maintenance of an internal steady state of divalent or trivalent inorganic anions at the level of a cell. GO:0030316 osteoclast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030316 osteoclast cell differentiation The process in which a relatively unspecialized monocyte acquires the specialized features of an osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue. GO:0030317 flagellated sperm motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030317 Wikipedia:Sperm_motility sperm flagellum movement involved in flagellated sperm movement|sperm flagellum movement|sperm flagellum movement involved in flagellated sperm motility|sperm motility|flagellated sperm movement|sperm movement The directed, self-propelled movement of a cilium (aka flagellum) that contributes to the movement of a flagellated sperm. GO:0005358 high-affinity glucose:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005358 high-affinity hydrogen:glucose transporter activity|high-affinity hydrogen/glucose transporter activity|high-affinity hydrogen:glucose symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. This activity is constitutive and therefore always present, regardless of demand. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. GO:0030314 junctional membrane complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030314 triad junction Complex formed in muscle cells between the membrane of the sarcoplasmic reticulum and invaginations of the plasma membrane (T-tubules). GO:0030315 T-tubule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030315 Wikipedia:T-tubule triad|transverse tubule Invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. The ends of T-tubules make contact with the sarcoplasmic reticulum membrane. GO:0005359 low-affinity glucose:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005359 low-affinity hydrogen:glucose symporter activity|low-affinity hydrogen:glucose transporter activity|low-affinity hydrogen/glucose transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + H(out)+ = glucose(in) + H(in)+. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. GO:0005356 glucose:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005356 hydrogen:glucose symporter activity|transepithelial hydrogen:glucose transporter activity|hydrogen:glucose transporter activity|transepithelial hydrogen/glucose transporter activity|transepithelial hydrogen:glucose symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. GO:0030312 external encapsulating structure biolink:CellularComponent go-plus goslim_chembl|goslim_plant|goslim_pir|goslim_drosophila|goslim_generic http://purl.obolibrary.org/obo/GO_0030312 A structure that lies outside the plasma membrane and surrounds the entire cell or cells. This does not include the periplasmic space. GO:0030313 cell envelope biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0030313 Wikipedia:Cell_envelope An envelope that surrounds a bacterial cell and includes the cytoplasmic membrane and everything external, encompassing the periplasmic space, cell wall, and outer membrane if present. GO:0005357 obsolete constitutive glucose:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005357 constitutive hydrogen:glucose transporter activity|constitutive hydrogen/glucose transporter activity|constitutive hydrogen:glucose symporter activity OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. This activity is constitutive and therefore always present, regardless of demand. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. RO:0002352 input of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002352 RO:0002352 inverse of has input GO:0005354 galactose transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005354 galactose/glucose (methylgalactoside) porter activity Enables the transfer of galactose from one side of a membrane to the other. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose. GO:0005355 glucose transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005355 Reactome:R-HSA-5653873|Reactome:R-HSA-499981 galactose/glucose (methylgalactoside) porter activity|glucose permease activity|lactose/glucose efflux transporter activity Enables the transfer of the hexose monosaccharide glucose from one side of a membrane to the other. RO:0002353 output_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002353 RO:0002353 inverse of has output GO:0005352 alpha-glucoside:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005352 general alpha-glucoside:proton symporter activity|alpha-glucoside:hydrogen symporter activity|general alpha-glucoside transporter activity|general alpha-glucoside:hydrogen symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: alpha-glucoside(out) + H+(out) = alpha-glucoside(in) + H+(in). Alpha-glucosides include trehalose, maltose, turanose, isomaltose, alpha-methylglucoside, maltotriose, palatinose, trehalose and melezitose. RO:0002354 formed as result of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002354 RO:0002354 GO:0005353 fructose transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005353 Reactome:R-HSA-189222 fructose porter activity|fructose permease activity Enables the transfer of fructose from one side of a membrane to the other. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey. RO:0002355 results in structural organization of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002355 RO:0002355 A relationship between a process and an anatomical entity such that the process contributes to the act of creating the structural organization of the anatomical entity. GO:0005350 pyrimidine nucleobase transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005350 pyrimidine base transmembrane transporter activity|pyrimidine transmembrane transporter activity Enables the transfer of pyrimidine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from one side of a membrane to the other. GO:0005351 carbohydrate:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005351 TC:2.A.1.1 cation/sugar symporter activity|hydrogen:sugar symporter activity|sugar transporter|sugar porter activity|sugar efflux transmembrane transporter activity|proton:sugar symporter activity|sugar:hydrogen symporter activity|sugar:proton symporter activity|sugar:hydrogen ion symporter activity|hydrogen:sugar transporter activity|lactose/glucose efflux transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: carbohydrate(out) + H+(out) = carbohydrate(in) + H+(in). RO:0002350 member of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002350 RO:0002350 RO:0002351 has member biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002351 RO:0002351 RO:0002349 results in determination of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002349 RO:0002349 p 'results in determination of' c if and only if p is a developmental process and c is a cell and p results in the state of c changing to be determined. Once a cell becomes determined, it becomes committed to differentiate down a particular pathway regardless of its environment. RO:0002345 exports biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002345 RO:0002345 Holds between p and c when p is a transportation or localization process and the outcome of this process is to move c to a destination that is part of some s, where the end location of c is part of the region that surrounds s. RO:0002348 results in commitment to biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002348 RO:0002348 p 'results in commitment to' c if and only if p is a developmental process and c is a cell and p results in the state of c changing such that is can only develop into a single cell type. GO:0030310 poly-N-acetyllactosamine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030310 poly-N-acetyllactosamine degradation|poly-N-acetyllactosamine catabolism|poly-N-acetyllactosamine breakdown The chemical reactions and pathways resulting in the breakdown of poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n. GO:0030311 poly-N-acetyllactosamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030311 poly-N-acetyllactosamine biosynthesis|poly-N-acetyllactosamine anabolism|poly-N-acetyllactosamine synthesis|poly-N-acetyllactosamine formation The chemical reactions and pathways resulting in the formation of poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n. GO:0019991 septate junction assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019991 The assembly of a septate junction, an intercellular junction found in invertebrate epithelia that is characterized by a ladder like appearance in electron micrographs and thought to provide structural strength and to provide a barrier to diffusion of solutes through the intercellular space. GO:0019992 diacylglycerol binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019992 Interacting selectively and non-covalently with diacylglycerol, a diester of glycerol and two fatty acids. GO:0019990 pteridine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019990 pteridine breakdown|pteridine catabolism|pteridine degradation The chemical reactions and pathways resulting in the breakdown of pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group. GO:0030307 positive regulation of cell growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030307 activation of cell growth|stimulation of cell growth|up-regulation of cell growth|upregulation of cell growth|up regulation of cell growth Any process that activates or increases the frequency, rate, extent or direction of cell growth. GO:0030308 negative regulation of cell growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030308 down-regulation of cell growth|inhibition of cell growth|down regulation of cell growth|downregulation of cell growth Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth. GO:0030305 heparanase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030305 Reactome:R-HSA-1678694|Reactome:R-HSA-1667005 heparinase activity Catalysis of the cleavage of heparan sulfate; can degrade both heparan sulfate and heparin glycosaminoglycan chains. GO:0030306 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030306 GO:0030303 obsolete stromelysin 2 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030303 stromelysin 2 activity|matrix metalloproteinase 10 activity|MMP-10|proteoglycanase 2|transin 2 activity OBSOLETE. Catalysis of the cleavage of peptide bonds in collagen with preferential cleavage where P1', P2' and P3' are hydrophobic residues; action on collagen types III, IV and V is weak. GO:0005369 taurine:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005369 sodium/chloride-dependent taurine transporter Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: taurine(out) + Na+(out) = taurine(in) + Na+(in). GO:0030304 obsolete trypsin inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030304 trypsin inhibitor activity OBSOLETE. Stops, prevents or reduces the activity of the serine endopeptidase trypsin. GO:0005367 myo-inositol:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005367 Reactome:R-HSA-429663 myo-inositol-sodium cotransporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: myo-inositol(out) + Na+(out) = myo-inositol(in) + Na+(in). GO:0030301 cholesterol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030301 The directed movement of cholesterol, cholest-5-en-3-beta-ol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0030302 deoxynucleotide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030302 The directed movement of a deoxynucleotide, a deoxyribonucleoside in ester linkage to phosphate, commonly at the 5' position of deoxyribose, into, out of or within a cell. GO:0005368 taurine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005368 RHEA:14613 Enables the transfer of taurine from one side of a membrane to the other. Taurine (2-aminoethanesulfonic acid) is a sulphur-containing amino acid derivative which is important in the metabolism of fats. RO:0002341 results in transport along biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002341 RO:0002341 Holds between p and l when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that is aligned_with l GO:0005365 myo-inositol transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005365 vitamin Bh transporter activity Enables the transfer of myo-inositol from one side of a membrane to the other. Myo-inositol is 1,2,3,4,5/4,6-cyclohexanehexol, a growth factor for animals and microorganisms. GO:0005366 myo-inositol:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005366 RHEA:60364|Reactome:R-HSA-429101 myo-inositol:hydrogen symporter activity|hydrogen/myo-inositol transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: myo-inositol(out) + H+(out) = myo-inositol(in) + H+(in). RO:0002342 results in transport across biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002342 RO:0002342 Holds between p and m when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that crosses m. RO:0002343 results in growth of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002343 RO:0002343 GO:0005363 maltose transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005363 RHEA:33171 maltose porter activity Enables the transfer of maltose from one side of a membrane to the other. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the enzymatic breakdown of glycogen and starch. GO:0005364 maltose:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005364 hydrogen/maltose transporter activity|maltose permease|maltose:hydrogen symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: maltose(out) + H+(out) = maltose(in) + H+(in). RO:0002344 results in transport to from or in biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002344 RO:0002344 GO:0005361 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005361 GO:0005362 low-affinity glucose:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005362 Reactome:R-HSA-429567 low-affinity glucose-sodium cotransporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations. GO:0030309 poly-N-acetyllactosamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030309 poly-N-acetyllactosamine metabolism The chemical reactions and pathways involving poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n. GO:0005360 insulin-responsive glucose:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005360 transepithelial hydrogen/glucose transporter activity|insulin-responsive hydrogen:glucose transporter activity|insulin-responsive hydrogen:glucose symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + H(out)+ = glucose(in) + H(in)+, in response to a stimulus by insulin. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. RO:0002340 imports biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002340 RO:0002340 Holds between p and c when p is a transportation or localization process and the outcome of this process is to move c to a destination that is part of some s, where the start location of c is part of the region that surrounds s. RO:0002338 has target start location biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002338 RO:0002338 This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from some initial location l to some destination. RO:0002339 has target end location biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002339 RO:0002339 This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from a an initial location to some destination l. RO:0002334 regulated by biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002334 RO:0002334 inverse of regulates RO:0002335 negatively regulated by biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002335 RO:0002335 inverse of negatively regulates RO:0002336 positively regulated by biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002336 RO:0002336 inverse of positively regulates RO:0002337 related via localization to biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002337 RO:0002337 A relationship that holds via some process of localization GO:0030300 regulation of intestinal cholesterol absorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030300 Any process that modulates the frequency, rate or extent of absorption of cholesterol into the blood, and the exclusion of other sterols from absorption. RO:0002331 involved in biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002331 RO:0002331 c involved_in p if and only if c enables some process p', and p' is part of p RO:0002332 regulates levels of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002332 RO:0002332 p regulates levels of c if p regulates some amount (PATO:0000070) of c RO:0002333 enabled by biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002333 RO:0002333 inverse of enables CHEBI:67375 noreugenin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67375 RO:0002327 enables biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002327 RO:0002327 RO:0002328 functionally related to biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002328 RO:0002328 A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities. RO:0002329 part of structure that is capable of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002329 RO:0002329 this relation holds between c and p when c is part of some c', and c' is capable of p. RO:0002323 mereotopologically related to biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002323 RO:0002323 A mereological relationship or a topological relationship RO:0002324 developmentally related to biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002324 RO:0002324 A relationship that holds between entities participating in some developmental process (GO:0032502) RO:0002320 evolutionarily related to biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002320 RO:0002320 A relationship that holds via some environmental process RO:0002322 confers_advantage_in biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002322 RO:0002322 adapted_for UBERON:0004099 joint space of elbow biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004099 synovial cavity of elbow joint Joint cavity shared by all the joints of the elbow. The elbow joint is a compound joint that actually comprises three separate joints: the joints connecting the upper and lower arm: 1) Articulatio humero-ulnaris and 2) Articulatio humero-radialis as well as the proximal joint connecting the forarm bones: 3) Articulatio radio-ulnaris proximalis. All three share a joint cavity which is highly sinuated/scalloped/coved. Joint spaces of the elbow summarizes the joint cavity shared by all three adjoining joints of the elbow joint. RO:0002313 transports or maintains localization of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002313 RO:0002313 Holds between p and c when p is a localization process (localization covers maintenance of localization as well as its establishment) and the outcome of this process is to regulate the localization of c. RO:0002314 inheres in part of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002314 RO:0002314 q inheres in part of w if and only if there exists some p such that q inheres in p and p part of w. RO:0002315 results in acquisition of features of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002315 RO:0002315 The relationship that links a specified entity with the process that results in an unspecified entity acquiring the features and characteristics of the specified entity UBERON:0004088 orbital region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004088 orbital content|content of orbital part of eye|orbital part of eye|orbital part of face|eye region|ocular and peri-ocular region|ocular region The subdivision of the face that includes the eye (eyeball plus adnexa such as eyelids) and the orbit of the skull and associated parts of the face such as the eyebrows, if present RO:0002305 causally upstream of, negative effect biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002305 RO:0002305 UBERON:0004089 midface biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004089 midface/lower face|lower face|snout The middle of the face including the nose and its associated bony structures[MW]. UBERON:0004086 brain ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004086 cerebral ventricle|region of ventricular system of brain|brain ventricles one of the system of communicating cavities in the brain that are continuous with the central canal of the spinal cord, that like it are derived from the medullary canal of the embryo, that are lined with an epithelial ependyma, and that contain a serous fluid CHEBI:18418 (RS)-norcoclaurine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18418 UBERON:0004087 vena cava biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004087 venae cavae|caval vein Any of the veins that carries deoxygenated blood from a part of the body into the right atrium of the heart. CHEBI:18419 lactaldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18419 CHEBI:18416 N-[(R)-pantothenoyl]-L-cysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18416 CHEBI:18417 (RS)-coclaurine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18417 CHEBI:18415 N-formimidoylglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18415 RO:0002304 causally upstream of, positive effect biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002304 RO:0002304 CHEBI:18412 N(omega)-phospho-L-arginine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18412 CHEBI:18413 2-formamido-N(1)-(5-phospho-D-ribosyl)acetamidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18413 CHEBI:18410 N-formylanthranilate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18410 CHEBI:18411 laminarabiose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18411 CHEBI:18409 (2S)-2-hydroxy-2-methyl-3-oxobutanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18409 CHEBI:18407 hydrogen cyanide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18407 CHEBI:18408 cobamamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18408 UBERON:0004073 cerebellum interpositus nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004073 interposed nucleus of the cerebellum|interpositus nucleus|interposed nucleus of the cerebellum|interposed nucleus|interposed nucleus of cerebellum|interpositus The nucleus composed of the globose and emoliform nuclei of the cerebellum; in some mammalian species the globose nucleus is not distinguishable CHEBI:18405 pyridoxal 5'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18405 CHEBI:18406 AICA ribonucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18406 CHEBI:18403 L-arabinitol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18403 CHEBI:18404 3-methylcatechol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18404 CHEBI:18401 phenylacetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18401 CHEBI:18402 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18402 CHEBI:18400 2-hydroxy-1,4-benzoquinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18400 GO:0030390 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030390 GO:0030391 fructosamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030391 fructosamine formation|fructosamine biosynthesis|fructosamine anabolism|fructosamine synthesis The chemical reactions and pathways resulting in the formation of fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group. GO:0030398 peroxisomal membrane disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030398 peroxisomal membrane degradation|peroxisomal membrane breakdown|peroxisomal membrane catabolism The controlled breakdown of the membranes of cargo-carrying vesicles formed during peroxisome degradation. GO:0030399 autophagosome membrane disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030399 autophagic membrane degradation|autophagic vacuole membrane disassembly|autophagic membrane catabolism|autophagic membrane breakdown The controlled breakdown of the membranes of autophagosomes. GO:0030396 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030396 GO:0030397 membrane disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030397 membrane catabolism|membrane degradation|membrane breakdown The controlled breakdown of any cell membrane in the context of a normal process such as autophagy. GO:0030394 fructoseglycine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030394 fructoseglycine metabolism The chemical reactions and pathways involving fructoseglycine, a fructose molecule containing a glycine group in place of a hydroxyl group. GO:0030395 lactose binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030395 Interacting selectively and non-covalently with lactose, a disaccharide of glucose and galactose, the carbohydrate of milk. GO:0030392 fructosamine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030392 fructosamine degradation|fructosamine catabolism|fructosamine breakdown The chemical reactions and pathways resulting in the breakdown of fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group. GO:0030393 fructoselysine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030393 fructoselysine metabolism The chemical reactions and pathways involving fructoselysine, a fructose molecule containing a lysine group in place of a hydroxyl group. GO:0030389 fructosamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030389 fructosamine metabolism The chemical reactions and pathways involving fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group. GO:0030380 interleukin-17E receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030380 interleukin-17E receptor ligand|IL-17E Interacting selectively and non-covalently with the interleukin-17E receptor. GO:0030387 fructosamine-3-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030387 Catalysis of the phosphorylation of fructosamine to form fructosamine-3-phosphate. GO:0030388 fructose 1,6-bisphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030388 fructose 1,6-bisphosphate metabolism The chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis. GO:0030385 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030385 GO:0030386 ferredoxin-thioredoxin reductase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030386 ferredoxin:thioredoxin reductase complex A protein complex that possesses ferredoxin-thioredoxin reductase activity. GO:0030383 obsolete host-pathogen interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030383 host-pathogen interaction OBSOLETE. Any interaction between a pathogen and its host organism. GO:0030384 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030384 GO:0030381 chorion-containing eggshell pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030381 The regionalization process that gives rise to the structural pattern of a chorion-containing eggshell such as those found in insects. GO:0030382 sperm mitochondrion organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030382 sperm mitochondrion organization and biogenesis|sperm mitochondria organization and biogenesis|sperm mitochondria organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of sperm mitochondria; the process in which they take on their characteristic morphology; they are flattened, elongated, and arranged circumferentially into a tight helical coil around the tail-dense fibers of the mature sperm. CHEBI:82929 1,2-dipalmitoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82929 CHEBI:18360 13-(2-methylcrotonoyloxy)lupanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18360 CHEBI:18361 diphosphate(4-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18361 CHEBI:82927 1-palmitoyl-2-linoleoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82927 CHEBI:82928 1-palmitoyl-2-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82928 CHEBI:57969 imidazol-4-ylacetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57969 CHEBI:82925 1,2-di[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82925 CHEBI:57967 ADP-D-ribose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57967 CHEBI:57968 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57968 CHEBI:82924 1,2-di[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82924 CHEBI:82921 1,2-dioctadecanoyl-sn-glycerol-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82921 UBERON:0004141 heart tube biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004141 endocardial tube|endocardial heart tube|embryonic heart tube An epithelial tube that will give rise to the mature heart. CHEBI:33992 (-)-catechin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33992 UBERON:0004142 outflow tract septum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004142 The outflow tract septum is a partition in the outflow tract UBERON:0004140 primary heart field biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004140 primary heart field|FHF|heart field|first heart field|PHF A specific region of the lateral mesoderm that will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle. CHEBI:18359 holo-[acyl-carrier protein] biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18359 CHEBI:57965 deacetoxyvindolinium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57965 CHEBI:18357 (R)-noradrenaline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18357 CHEBI:18358 methoxsalen biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18358 CHEBI:57966 beta-alanine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57966 CHEBI:18355 2-hydroxypenta-2,4-dienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18355 CHEBI:57963 vitexin-7-olate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57963 UBERON:0004149 ventriculo bulbo valve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004149 bulboventricular valve A heart valve located between the ventricle and bulbus arteriosus. CHEBI:18356 pyrroloquinoline quinol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18356 CHEBI:57964 GDP-4-dehydro-6-deoxy-alpha-D-mannose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57964 CHEBI:18353 vanillyl alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18353 CHEBI:18354 (R)-2-hydroxypropyl-CoM biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18354 CHEBI:57962 5-hydroxymethyldeoxycytidylate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57962 UBERON:0004148 cardiac vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004148 cardiac vein|coronary vein|heart vein|coronary vein|vein of heart Vein of heart that drains the myocardium CHEBI:18351 4-hydroxyhexan-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18351 UBERON:0004145 outflow tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004145 arterial (outflow) pole|heart outflow tract|cardiac outflow tract The outflow tract is the portion of the heart through which blood flows into the arteries UBERON:0004146 His-Purkinje system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004146 HPS|His-Purkinji network The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles CHEBI:18350 isoquinolin-1(2H)-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18350 CHEBI:82939 beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)-[alpha-N-acetylneuraminosyl-(2->8)-alpha-N-acetylneuraminosyl-(2->3)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82939 CHEBI:57958 (R)-2,4-dihydroxy-3-oxobutanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57958 CHEBI:57959 L-kynurenine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57959 CHEBI:57956 3-amino-3-(4-hydroxyphenyl)propanoic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57956 CHEBI:57957 lipid X(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57957 CHEBI:82930 3-(3-amino-3-carboxypropyl)uridine 5'-phosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82930 GO:0019908 nuclear cyclin-dependent protein kinase holoenzyme complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019908 CDK holoenzyme Cyclin-dependent protein kinase (CDK) complex found in the nucleus. GO:0019909 [pyruvate dehydrogenase (lipoamide)] phosphatase regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019909 [pyruvate dehydrogenase (lipoamide)] phosphatase, intrinsic regulator activity Modification of the activity of the enzyme [pyruvate dehydrogenase (lipoamide)] phosphatase. GO:0019906 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019906 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019907 IntAct:EBI-9868598|IntAct:EBI-1246076 CAK complex|CDK-activating kinase complex A cyclin-dependent kinase activating kinase complex capable of activating cyclin-dependent kinases by threonine phosphorylation, thus regulating cell cycle progression. consists of a kinase, cyclin and optional assembly factors, in human CDK7, CCNH and MNAT1. CAK activity is itself regulated throughout the cell cycle by T-loop phosphorylation of its kinase component (CDK7 in human). Phosphorylation of serine residues during mitosis inactivates the enzyme. Also capable of CAK phosphorylating the carboxyl-terminal domain (CTD) of RNA polymerase II and other transcription activating proteins, as part of the general transcription factor TFIIH. GO:0019904 protein domain specific binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0019904 protein domain-specific binding Interacting selectively and non-covalently with a specific domain of a protein. UBERON:0004132 trigeminal sensory nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004132 sensory trigeminal nucleus|trigeminal sensory nucleus|sensory trigeminal nuclei|sensory trigeminal V nucleus|trigeminal V sensory nucleus The sensory trigeminal nerve nuclei are the largest of the cranial nerve nuclei, and extend through the whole of the midbrain, pons and medulla. The nucleus is divided into three parts, from rostral to caudal (top to bottom in humans): * The mesencephalic nucleus * The chief sensory nucleus (or pontine nucleus or main sensory nucleus or primary nucleus) * The spinal trigeminal nucleus[WP]. UBERON:0004133 salivatory nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004133 salivary nucleus . GO:0019905 syntaxin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019905 syntaxin-6 binding|syntaxin-5 binding|syntaxin-2 binding|syntaxin-13 binding Interacting selectively and non-covalently with a syntaxin, a SNAP receptor involved in the docking of synaptic vesicles at the presynaptic zone of a synapse. UBERON:0004130 cerebellar layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004130 layer of cerebellum|gray matter layer of cerebellum|layer of cerebellar cortex|cell layer of cerebellar cortex|cytoarchitectural part of the cerebellar cortex A cortical cell layer of the cerebellum. Examples: the granular (inner+outer) layer, molecular layer, Purkinje cell layer, and the ventricular layer of the embryo. GO:0019902 phosphatase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019902 Interacting selectively and non-covalently with any phosphatase. GO:0019903 protein phosphatase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019903 Interacting selectively and non-covalently with any protein phosphatase. GO:0019900 kinase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019900 Interacting selectively and non-covalently with a kinase, any enzyme that catalyzes the transfer of a phosphate group. GO:0019901 protein kinase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019901 Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate. CHEBI:18348 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18348 CHEBI:18349 N(1)-(5-phospho-D-ribosyl)glycinamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18349 CHEBI:18346 vanillin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18346 CHEBI:57954 3-cyano-L-alaninate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_57954 CHEBI:57955 6-O-phosphonato-D-glucono-1,5-lactone(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57955 CHEBI:18347 L-norleucine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18347 CHEBI:57952 sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57952 CHEBI:18344 kynurenic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18344 UBERON:0004138 somitomeric trunk muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004138 The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. An example of this process is found in Mus musculus.[GO]. UBERON:0004139 cardiogenic plate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004139 myocardial plate|cardiogenic crescent|cardiac crescent|heart rudiment The first recognizable structure derived from the heart field CHEBI:57953 UDP-N-acetylmuramoyl-L-alaninate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57953 UBERON:0004136 intermediate tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004136 tubulus attenuatus|renal intermediate tubule The intermediate tubule is a nephron tubule that lies between the proximal and distal tubules CHEBI:57951 L-saccharopinate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57951 UBERON:0004134 proximal tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004134 kidney proximal tubule|proximal kidney tubule|renal proximal tubule In mammals, the proximal tubule is a nephron tubule that connects Bowman's capsule to the loop of Henle. It has a brush border epithelial morphology[GO]. CHEBI:18340 cis-1,6-dihydroxycyclohexa-2,4-dienecarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18340 UBERON:0004135 distal tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004135 renal distal tubule|kidney distal tubule The distal tubule is a nephron tubule that consists of the distal convoluted tubule and distal straight tubule segments CHEBI:18341 diacetylchitobiosyldiphosphodolichol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18341 CHEBI:18383 3-aminoalanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18383 CHEBI:57949 6-phosphonato-5-dehydro-2-deoxy-D-gluconate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57949 CHEBI:82949 1-palmitoyl-2-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82949 CHEBI:18380 2,3,2',3'-tetrakis(3-hydroxytetradecanoyl)-alpha-D-glucosaminyl-1,6-beta-D-glucosamine 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18380 CHEBI:18381 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18381 CHEBI:57947 creatine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57947 CHEBI:82947 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3'-phosphate) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82947 CHEBI:57948 5-oxo-D-prolinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57948 CHEBI:82948 1,2-dipalmitoylglycero-3-phospho-(1'-D-myo-inositol-3'-phosphate) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82948 CHEBI:57945 NADH(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57945 CHEBI:82945 N-acetyl-beta-D-galactosaminyl-(1->4)-[alpha-N-acetylneuraminosyl-(2->3)]-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)-[alpha-N-acetylneuraminosyl-(2->3)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82945 CHEBI:57946 N-methylphenylethanolaminium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57946 CHEBI:82943 1-palmitoyl-2-icosanoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82943 CHEBI:33976 magnesium coordination entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33976 CHEBI:82940 alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)-[alpha-N-acetylneuraminosyl-(2->8)-alpha-N-acetylneuraminosyl-(2->3)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82940 UBERON:0004121 ectoderm-derived structure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004121 ectodermal deriviative An anatomical structure that develops (entirely or partially) from the ectoderm. UBERON:0004122 genitourinary system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004122 urogenital tract|UG tract|genitourinary tract|Urogenitalsystem|genito-urinary system|GU tract|urogenital system Anatomical system that has as its parts the organs concerned with the production and excretion of urine and those concerned with reproduction. CHEBI:33970 elemental gold biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33970 UBERON:0004120 mesoderm-derived structure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004120 mesodermal derivative An anatomical structure that develops (entirely or partially) from the mesoderm. CHEBI:33973 elemental magnesium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33973 CHEBI:18379 nitrile biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18379 UBERON:0004129 growth plate cartilage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004129 growth plate cartilage that will provide a scaffold for mineralization of endochondral bones as they elongate or grow. CHEBI:18377 N-formylkynurenine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18377 UBERON:0004127 compact layer of ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004127 ventricular myocardial compact zone|compact cardiac ventricle muscle|ventricular myocardial compact layer|ventricular compact myocardium|ventricle myocardium compact zone The outer layer the ventricular myocardium, muscle fibers are arranged in a compact form and involved the entire ventricle. UBERON:0004128 optic vesicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004128 optic vesicles|eye vesicle|evagination|ocular vesicle The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup[GO]. Portion of tissue that is comprised of neuroepitheium which has pinched off from the anterior neural keel and will form the optic cup[ZFA]. CHEBI:57942 chlorophyllide a(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_57942 CHEBI:18378 4alpha-methyl-5alpha-cholest-7-en-3beta-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18378 UBERON:0004125 myocardial compact layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004125 myocardium compact layer|compact subepicardial myocardium|subepicardium layer|heart compact layer|compact subepicardial layer|subepicardial layer|myocardial compact layer|subepicardium outer dense layer of the myocardium uniting the epicardium and myocardium[MP]. CHEBI:18375 nucleoside 3',5'-cyclic phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18375 CHEBI:18376 dermatan sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18376 UBERON:0004126 trabecular layer of ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004126 ventricular trabecular myocardium|trabecular cardiac ventricle muscle|myocardium of region of ventricle A myocardium trabecular layer that is part of a cardiac ventricle. CHEBI:57940 3-sulfonatopyruvate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57940 UBERON:0004123 myocardial layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004123 layer of myocardium|myocardium layer Any of the layers of the myocardium. Example: compact layer, trabecular layer. CHEBI:18373 (7S)-salutaridinol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18373 UBERON:0004124 myocardium trabecular layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004124 heart muscle trabeculae|myocardial trabeculae carneae|trabecula of heart muscle|trabecular layer|myocardial trabecular layer|trabeculae|heart muscle trabecula The layer of the myocardium composed of projections of contractile myocytes. The trabecular layer is bounded internally by the endocardium. In zebrafish, unlike the trabeculations of higher vertebrates, both atrial and ventricular trabeculae have more strut-like character, and are more uniform without apparent regional differences[ZFA]. CHEBI:18374 1-(5-phospho-beta-D-ribosyl)-5'-AMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18374 CHEBI:18371 cis-4-carboxymethylenebut-2-en-4-olide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18371 CHEBI:18372 7,8-dihydroneopterin 3'-triphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18372 CHEBI:57938 trans-3-hydroxy-L-proline zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57938 CHEBI:18370 7-deoxyloganin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18370 CHEBI:57939 sphinganine 1-phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57939 CHEBI:57936 N-acetyl-L-gamma-glutamyl phosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57936 CHEBI:82959 N-hexanoylsphingosine 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82959 CHEBI:57937 2-aminomuconate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_57937 CHEBI:57934 psychosine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57934 CHEBI:82957 3-hydroxyisovalerate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82957 CHEBI:57935 oxidized Watasenia luciferin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57935 CHEBI:82954 1,2-dipalmitoyl-sn-glycero-3-phospho-(1'D-myo-inositol-3',5'-bisphosphate) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82954 CHEBI:82953 1-(3-O-sulfonato-beta-D-galactosyl)ceramide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82953 CHEBI:82950 N-acetyl-beta-D-galactosaminyl-(1->4)-[alpha-N-glycoloylneuraminosyl-(2->3)]-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82950 CHEBI:82951 alpha-N-glycoloylneuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82951 UBERON:0004111 anatomical conduit biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004111 opening|foramina|ostium|foramen|ostia Any tube, opening or passage that connects two distinct anatomical spaces. CHEBI:33980 quinovose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33980 CHEBI:33983 deoxymannose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33983 CHEBI:33984 fucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33984 CHEBI:33985 muramates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33985 CHEBI:33986 muramate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33986 UBERON:0004118 vasculature of iris biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004118 iris vasculature|vascular network of iris|iris blood vessels|iris vascular network A vasculature that is part of a iris [Automatically generated definition]. CHEBI:18368 D-glucosyl-N-acylsphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18368 CHEBI:57932 D-methionine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57932 UBERON:0004119 endoderm-derived structure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004119 An anatomical structure that develops (entirely or partially) from the endoderm. CHEBI:57933 oleandomycin(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57933 UBERON:0004116 nerve of tympanic cavity biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004116 nerve of middle ear cavity|middle ear cavity nerve|cavity of middle ear nerve|nerve of anatomical cavity of middle ear|nerve of middle ear anatomical cavity|tympanic cavity nerve|anatomical cavity of middle ear nerve|middle ear anatomical cavity nerve|tympanic cavity nerves|nerve of cavity of middle ear A nerve that is part of a tympanic cavity [Automatically generated definition]. CHEBI:18366 Arg-tRNA(Arg) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18366 CHEBI:57930 nucleoside 5'-diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57930 UBERON:0004117 pharyngeal pouch biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004117 visceral pouch|branchial pouch|pharyngeal pouches|visceral pouches An internal pocketing of pharyngeal endoderm that contacts a region of ectoderm (a pharyngeal cleft) and interdigitates in the anterior and posterior directions with the pharyngeal arches. CHEBI:57931 D-ribofuranosyl-ADP(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57931 CHEBI:18367 phosphate(3-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18367 UBERON:0004114 tympanic cavity biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004114 middle-ear cavity|middle ear cavity|cavity of middle ear|cavitas tympani|tympanum|anatomical cavity of middle ear|cavitas tympanica small cavity surrounding the bones of the middle ear. CHEBI:18364 14-demethyllanosterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18364 UBERON:0004115 blood vessel of tympanic cavity biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004115 anatomical cavity of middle ear blood vessel|tympanic cavity blood vessel|cavity of middle ear blood vessel|middle ear cavity blood vessel|middle ear blood vessel|blood vessel of cavity of middle ear|blood vessel of middle ear cavity|blood vessel of middle ear anatomical cavity|blood vessel of anatomical cavity of middle ear|middle ear anatomical cavity blood vessel A blood vessel that is part of a tympanic cavity [Automatically generated definition]. CHEBI:18365 naphthalene-1,3,6,8-tetrol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18365 CHEBI:18362 17-O-deacetylvindoline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18362 UBERON:0004113 muscle of auditory ossicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004113 muscle of tympanic cavity|tympanic cavity muscle|muscle of middle ear|ossicular muscle|muscle of auditory ossicles|auditory ossicles muscle A muscle of the tympanic cavity that attaches to an auditory ossicle. CHEBI:18363 reticulinylium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18363 CHEBI:57929 7''-O-phosphohygromycin B(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57929 CHEBI:57927 oxaloacetate 4-methyl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57927 CHEBI:57928 3',4',5-trihydroxy-3-methoxyflavon-7-olate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57928 CHEBI:57925 glutathionate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57925 CHEBI:57926 L-threonine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57926 CHEBI:82967 (11Z)-3-oxohexadecenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82967 CHEBI:57923 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57923 CHEBI:57924 L-dopaquinone zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57924 CHEBI:33954 tagatose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33954 UBERON:0004180 mammary gland fat biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004180 fat tissue of lactiferous gland|adipose tissue of lactiferous gland|lactiferous gland fatty tissue|lobe of mammary gland adipose tissue|fatty tissue of mammary gland|lobe of mammary gland fat tissue|lobe of breast adipose tissue|fat tissue of mammary gland|fat tissue of lobe of breast|lobe of mammary gland fatty tissue|lobe of breast fat tissue|adipose tissue of mammary gland|fatty tissue of lobe of breast|lobe of breast fatty tissue|mammary gland adipose tissue|fatty tissue of lobe of mammary gland|mammary gland fat tissue|fat tissue of lobe of mammary gland|mammary gland fatty tissue|fatty tissue of lactiferous gland|lactiferous gland adipose tissue|lactiferous gland fat tissue The mammary fat is an adipose structure in the gland that is invaded by the mammary ducts CHEBI:33956 ribulose derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33956 CHEBI:82963 1,2-dipalmitoyl-sn-glycero-3-phospho-(1'D-myo-inositol-3'-phosphate) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82963 CHEBI:33957 xylulose derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33957 CHEBI:82961 17beta-estradiol 17-glucosiduronate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82961 CHEBI:33958 halide salt biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33958 UBERON:0004187 Harderian gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004187 Harder's gland|glandula palpebra tertia profundus|deep gland of the nictitating membrane|Hardarian gland|gland of Hardarian The Harderian gland is an anterior orbital gland usually associated with the nictitating membrane, and produces and secretes a variety of substances to the eye, depending upon the species[GO]. UBERON:0004188 glomerular epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004188 glomerular epithelial cell|epithelium of kidney glomerulus|epithelium of glomerulus|epithelium of renal glomerulus|kidney glomerular epithelium The glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus. The glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros. CHEBI:18319 SAICAR biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18319 UBERON:0004185 endodermal part of digestive tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004185 gut endoderm|endodermal gut A portions of the gut that is derived from endoderm. UBERON:0004186 olfactory bulb mitral cell layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004186 mitral cell layer of the olfactory bulb|mitral cell body layer|olfactory bulb main mitral cell body layer|mitral cell layer|OB mitral cell layer The mitral cell layer is composed of pyramidal neurons whose cell bodies are located between the granule cell layer and the plexiform layer UBERON:0004183 placental labyrinth blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004183 blood vessel of placenta labyrinth|blood vessel of labyrinthine layer|blood vessel of labyrinthine layer of placenta|labyrinthine layer of placenta blood vessel|labyrinthine layer blood vessel|placenta labyrinth blood vessel The embryonic vessels grow through the layer to come in close contact with the maternal blood supply CHEBI:18317 N-acetyl-LL-2,6-diaminopimelate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18317 UBERON:0004184 prostate gland stroma biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004184 prostatic stroma|stroma of prostate gland|prostate stroma|stroma of glandular part of prostate|stroma of prostate The prostate gland stroma is made up of the mesenchymal or fibroblast cells of the prostate gland CHEBI:18318 galactosylceramide sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18318 CHEBI:33951 psicose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33951 CHEBI:33952 sorbose derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33952 CHEBI:18315 pyrroloquinoline quinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18315 CHEBI:33953 tagatose derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33953 CHEBI:18316 4-ethylamino-6-isopropylamino-1,3,5-triazin-2-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18316 UBERON:0004182 mammary gland cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004182 lactiferous gland cord|mammary cord|mammary sprout The solid cord of epithelial cells that emerges from the mammary bud and grows down from the primary mammary mesenchyme and into a second stromal compartment, the fat pad precursor, beneath the dermis. CHEBI:18313 alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18313 CHEBI:57921 N(3')-acetyl-2-deoxystreptamine antibiotic(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57921 PO:0004010 meristematic cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0004010 célula meristemática (Spanish, exact)|分裂組織細胞 (Japanese, exact)|stem cell (exact) A native plant cell (PO:0025606) synthesizing protoplasm and producing new cells by division and with only a primary cell wall. CHEBI:57922 coenzyme gamma-F420-2(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57922 CHEBI:18314 L-2-aminopentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18314 CHEBI:18311 quinoline-4-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18311 CHEBI:57920 bis(3-azaniumylpropyl)azanium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57920 CHEBI:18312 4-(hydroxymethyl)benzenesulfonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18312 PO:0004013 epidermal cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0004013 célula epidérmica (Spanish, exact)|表皮細胞 (Japanese, exact) A native plant cell (PO:0025606) that is part of a portion of epidermis (PO:0005679). CHEBI:18310 alkane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18310 PO:0004011 initial cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0004011 célula inicial (Spanish, exact)|meristemoid (exact)|stem cell (related)|始原細胞 (Japanese, exact)|initial (exact) A meristematic cell (PO:0004010) that by division gives rise to two cells, one of which remains meristematic, while the other is added to the plant body. UBERON:0004189 glomerular endothelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004189 endothelium of renal glomerulus|renal glomerulus endothelium The glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus CHEBI:57918 alpha-ribazole 5'-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57918 CHEBI:57919 4-CDP-2-C-methyl-D-erythritol 2-phosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57919 CHEBI:57916 3-hexaprenyl-4-hydroxy-5-methoxybenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57916 CHEBI:57917 4-nitrophenolate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57917 CHEBI:57914 kievitone-7-olate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_57914 CHEBI:57915 L-gamma-glutamyl-D-alaninate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57915 CHEBI:57912 L-tryptophan zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57912 CHEBI:67347 (+)-pisatin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67347 CHEBI:33966 elemental silver biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33966 CHEBI:33969 gold molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33969 CHEBI:82972 3alpha-hydroxy-3,5-dihydromonacolin L acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82972 CHEBI:82970 dihydromonacolin L acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82970 CHEBI:82971 monacolin J acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82971 UBERON:0004176 external genitalia biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004176 external genitalia|external reproductive organ|external sex organ The external genitalia are the outer sex organs, such as the penis or vulva in mammals UBERON:0004177 hemopoietic organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004177 hematopoeitic organ|organ of haemopoietic system|lymph organ|lymphoid organ|organ of haematological system|organ of organa haemopoietica|hematopoeitic or lymphoid organ|organ of hematopoietic system|organa haemopoietica organ|haemopoietic system organ|hematopoietic system organ|haematological system organ Organ that is part of the hematopoietic system. CHEBI:18308 acrylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18308 UBERON:0004175 internal genitalia biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004175 internal sex organ|internal reproductive organ|internal genitalia|internal genitals The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals CHEBI:18306 thiamine(1+) carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18306 UBERON:0004172 pons reticulospinal tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004172 Axon tract that carries efferent (outgoing) action potentials from the cell body in the pons towards target cells in the spinal cord. CHEBI:18307 UDP-D-galactose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18307 UBERON:0004173 medulla reticulospinal tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004173 medullary reticulospinal tract Axon tract that carries efferent (outgoing) action potentials from the cell body in the medulla towards target cells in the spinal cord[GO]. UBERON:0004170 spinal cord ventral commissure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004170 anterior white commissure|ventral spinal commissure|ventral white column|spinal cord anterior commissure|anterior white commissure of spinal cord|white commissure|commissura alba anterior medullae spinalis|alba anterior medullae spinalis|ventral commissure of the spinal cord|ventral white commissure of spinal cord|anterior commissure The band of nerve fibers which cross the midline of the spinal cord ventral to the central canal and posterior grey commissure[MP]. The anterior (or ventral) white commissure, also known as the alba anterior medullae spinalis, is a bundle of nerve fibers which cross the midline of the spinal cord just anterior to the gray commissure. A N4 fibers and C fibers carrying pain sensation in the spinothalamic tract contribute to this commissure, as do fibers of the anterior corticospinal tract, which carry motor signals from the primary motor cortex[WP]. CHEBI:18304 deamido-NAD(+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18304 UBERON:0004171 trigeminothalamic tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004171 trigeminal tract|tractus trigeminothalamicus The trigeminothalamic tract is one of the major routes of nociceptive and temperature signaling from the face CHEBI:18305 hydroquinone O-beta-D-glucopyranoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18305 CHEBI:33964 silver molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33964 CHEBI:18302 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18302 CHEBI:18303 phosphatidyl-L-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18303 CHEBI:18300 maleic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18300 CHEBI:18301 (2Z,4E)-4-hydroxymuconic semialdehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18301 UBERON:0004178 aorta smooth muscle tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004178 aortic smooth muscle|aorta non-striated muscle|aorta smooth muscle the nonstriated, involuntary muscle tissue located in the wall of the aorta UBERON:0004179 prostate glandular acinus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004179 prostatic acinus|prostatic follicle A saclike structure of the prostate gland, comprised of at least three cell layers: an innermost layer of secretory columnar luminal epithelium, a middle layer of squamous basal epithelium that also contains neuroendocrine cells, transit amplifying cells, and stem cells, and an outer layer of smooth muscle intermixed with other stromal cells CHEBI:57907 all-trans-pentaprenyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57907 CHEBI:57908 N-benzoyl-D-arginine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57908 CHEBI:57905 dehydroepiandrosterone sulfate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57905 CHEBI:57906 trans-4-hydroxycyclohexanecarboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57906 CHEBI:57903 [1-(5-phosphonatoribosyl)imidazol-4-yl]acetate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57903 CHEBI:57904 D-glucose 6-sulfate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57904 CHEBI:57901 L-threo-3-phenylserine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57901 CHEBI:57902 1-benzyl-1,2,3,4-tetrahydroisoquinolin-2-ium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57902 CHEBI:82987 monacolin L acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82987 CHEBI:82985 mevinolinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82985 CHEBI:82983 1-oleoyl-2-acyl-sn-3-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82983 CHEBI:33937 macronutrient biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33937 CHEBI:57909 kanamycin A 3'-phosphate(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57909 CHEBI:82982 glycodeoxycholate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82982 UBERON:0004166 superior reticular formation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004166 . UBERON:0004164 branchiomeric muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004164 branchiomeric skeletal muscle|branchial head muscle A jaw muscle that arises from cranial mesenchyme and is innervated by cranial nerves. UBERON:0004161 septum transversum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004161 transverse septum A thick plate of mesodermal tissue that occupies the space between the thoracic cavity and yolk stalk in the early embryo, forming a transverse partition partially separating the coelomic cavity into thoracic and abdominal portions. It gives rise to the central tendon of the diaphragm[VHOG]. UBERON:0004162 pulmonary myocardium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004162 The pulmonary myocardium is the myocardial tissue present in the pulmonary vein CHEBI:18337 5-amino-6-(5-phospho-beta-D-ribosylamino)uracil biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18337 UBERON:0004160 proepicardium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004160 proepicardial cluster|proepicardial organ An embryonic group of progenitor cells that forms from an outpouching of the septum transversum near the venous pole of the heart and gives rise to the epicardium CHEBI:18335 pyridoxamine 5'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18335 CHEBI:18336 4-(phosphonooxy)-L-threonine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18336 CHEBI:57900 oxidized Photinus luciferin(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_57900 CHEBI:18333 D-arabinitol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18333 CHEBI:18334 adenosine 5'-(pentahydrogen tetraphosphate) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18334 CHEBI:18332 L-thyroxine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18332 UBERON:0004167 orbitofrontal cortex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004167 orbital frontal cortex|orbito-frontal cortex|segment of cortex of frontal lobe|fronto-orbital cortex The region of the cerebral cortex covering the basal surface of the frontal lobes; this region normally controls emotion and decision making CHEBI:18330 isovitexin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18330 CHEBI:33946 erythrose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33946 CHEBI:33947 threose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33947 CHEBI:33949 ketoheptose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33949 UBERON:0004154 atrial septum primum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004154 septum primum|atrial septum primum|interatrial septum primum In the developing heart, the cavity of the primitive atrium becomes subdivided into right and left chambers by a septum, the septum primum, which grows downward into the cavity. The increasingly smaller gap below it (before it fuses with the endocardial cushion) is known as the ostium primum. The septum primum eventually fuses with the endocardial cushion, closing the ostium primum off completely. Meanwhile, perforations appear in the superior part of the septum primum, forming the ostium secundum. This will eventually form part of the fossa ovalis. UBERON:0004155 atrial septum secundum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004155 septum secundum|interatrial septum secundum . UBERON:0004152 bulbus arteriosus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004152 truncus The bulbus arteriosus is an elastic heart chamber[GO]. Multi-tissue structure that consists of three layers and through which the blood exits the heart. The bulbus arteriosus is a pear shaped chamber that functions as a capacitor, maintaining continuous blood flow into the gill arches[ZFA]. UBERON:0004153 ventricular septum intermedium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004153 septum intermedium Endocardial cushions project into the atrial canal, and, meeting in the middle line, unite to form the septum intermedium which divides the canal into two channels, the future right and left atrioventricular orifices[Gray's via WP]. UBERON:0004150 coronary sinus valve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004150 thebesian valve|thebesius valve|valve of coronary sinus Vestigial cardiac valve which is continuous with the valve of the inferior vena cava[FMA]. CHEBI:18328 13-hydroxylupanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18328 CHEBI:18329 5alpha-androstane-3beta,17beta-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18329 UBERON:0004151 cardiac chamber biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004151 heart chamber|chamber of heart A cardiac chamber surrounds an enclosed cavity within the heart CHEBI:33942 ribose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33942 CHEBI:18327 N-formimidoyl-L-glutamate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18327 CHEBI:18325 2-succinatobenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18325 CHEBI:18322 6-oxohexanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18322 CHEBI:18323 anserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18323 CHEBI:18320 1,4-dithiothreitol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18320 UBERON:0004159 atrial septum intermedium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004159 . CHEBI:18321 1-(sn-glycero-3-phospho)-1D-myo-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18321 GO:0005338 nucleotide-sugar transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005338 Reactome:R-HSA-744231|Reactome:R-HSA-744230 Enables the transfer of a nucleotide-sugar from one side of a membrane to the other. A nucleotide-sugar is any nucleotide in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative. GO:0005339 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005339 GO:0005336 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005336 GO:0005337 nucleoside transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005337 RHEA:27318|Reactome:R-HSA-109529|Reactome:R-HSA-727740|Reactome:R-HSA-109534|Reactome:R-HSA-5628807|Reactome:R-HSA-727768|Reactome:R-HSA-109527|Reactome:R-HSA-727749|Reactome:R-HSA-109536|Reactome:R-HSA-727767 intracellular nucleoside transmembrane transporter activity Enables the transfer of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide) from one side of a membrane to the other. GO:0005334 norepinephrine:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005334 Reactome:R-HSA-5659764|Reactome:R-HSA-443997|Wikipedia:Norepinephrine_transporter noradrenaline transporter activity|norepinephrine:sodium:chloride symporter activity|levarterenol transporter activity|sodium/norepinephrine symporter activity|norepinephrine transmembrane transporter activity|norepinephrine:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: norepinephrine(out) + Na+(out) + Cl-(out) = norepinephrine(in) + Na+(in) + Cl-(in). NCBITaxon:6159 Tricladida organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_6159 GO:0005335 serotonin:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005335 RHEA:51196|Reactome:R-HSA-444008 serotonin:sodium:chloride symporter activity|sodium/serotonin symporter activity|serotonin transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: serotonin(out) + Na+(out) + Cl-(out) = serotonin(in) + Na+(in)+ Cl-(in). GO:0005332 gamma-aminobutyric acid:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005332 Reactome:R-HSA-444007 4-aminobutyrate:sodium symporter activity|GABA:sodium symporter activity|betaine/GABA:sodium symporter activity|sodium/chloride-dependent GABA transporter activity|4-aminobutanoate:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: gamma-aminobutyric acid(out) + Na+(out) = gamma-aminobutyric acid(in) + Na+(in). GO:0005333 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005333 GO:0005330 dopamine:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005330 dopamine:sodium:chloride symporter activity|sodium/dopamine symporter activity|dopamine transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dopamine(out) + Na+(out) + Cl-(out)= dopamine(in) + Na+(in) + Cl-(in). GO:0005331 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005331 GO:0019979 interleukin-4 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019979 IL-4 binding Interacting selectively and non-covalently with interleukin-4. GO:0019977 interleukin-21 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019977 IL-21 binding Interacting selectively and non-covalently with interleukin-21. GO:0019978 interleukin-3 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019978 IL-3 binding Interacting selectively and non-covalently with interleukin-3. GO:0019975 interleukin-17 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019975 IL-17 binding Interacting selectively and non-covalently with any member of the interleukin-17 family of cytokines. GO:0019976 interleukin-2 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019976 IL-2 binding Interacting selectively and non-covalently with interleukin-2. GO:0019973 interleukin-13 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019973 IL-13 binding Interacting selectively and non-covalently with interleukin-13. GO:0019974 interleukin-14 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019974 IL-14 binding Interacting selectively and non-covalently with interleukin-14. GO:0019972 interleukin-12 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019972 IL-12 binding Interacting selectively and non-covalently with interleukin-12. GO:0019970 interleukin-11 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019970 IL-11 binding Interacting selectively and non-covalently with interleukin-11. GO:0005349 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005349 GO:0005347 ATP transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005347 Enables the transfer of ATP, adenosine triphosphate, from one side of a membrane to the other. GO:0005348 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005348 GO:0005345 purine nucleobase transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005345 purine base transmembrane transporter activity|purine transmembrane transporter activity Enables the transfer of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from one side of a membrane to the other. CHEBI:149759 2-methyl-L-serine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_149759 GO:0005346 purine ribonucleotide transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005346 Enables the transfer of a purine ribonucleotide, any compound consisting of a purine ribonucleoside (a purine organic base attached to a ribose sugar) esterified with (ortho)phosphate, from one side of a membrane to the other. GO:0005343 organic acid:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005343 Reactome:R-HSA-8876312 sodium/chloride-dependent organic acid cotransporter activity|sodium:dicarboxylate/tricarboxylate symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: organic acid(out) + Na+(out) = organic acid(in) + Na+(in). GO:0005344 oxygen carrier activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005344 oxygen-carrying|hemerythrin|hemocyanin|globin Binding to oxygen and delivering it to an acceptor molecule or a specific location. GO:0005341 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005341 GO:0005342 organic acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005342 Enables the transfer of organic acids from one side of a membrane to the other. Organic acids are acidic compound containing carbon in covalent linkage. GO:0005340 nucleotide-sulfate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005340 nucleotide-sulphate transporter activity Enables the transfer of nucleotide-sulfate from one side of a membrane to the other. GO:0019988 charged-tRNA amino acid modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019988 pre-translational amino acid modification|pretranslation protein modification|charged-tRNA modification|pre-translational protein modification|charged tRNA amino acid modification|charged tRNA modification|pretranslational amino acid modification The covalent alteration of an amino acid charged on a tRNA before it is incorporated into a protein, as in N-formylmethionine, selenocysteine or pyrrolysine. GO:0019986 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019986 GO:0019987 obsolete negative regulation of anti-apoptosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019987 negative regulation of anti-apoptosis|down-regulation of anti-apoptosis|downregulation of anti-apoptosis|down regulation of anti-apoptosis|inhibition of anti-apoptosis OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of anti-apoptosis. GO:0019984 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019984 GO:0019985 translesion synthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019985 bypass DNA synthesis The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized DNA polymerase or replication complex inserts a defined nucleotide across from the lesion which allows DNA synthesis to continue beyond the lesion. This process can be mutagenic depending on the damaged nucleotide and the inserted nucleotide. GO:0019982 interleukin-7 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019982 IL-7 binding Interacting selectively and non-covalently with interleukin-7. GO:0019983 interleukin-9 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019983 IL-9 binding Interacting selectively and non-covalently with interleukin-9. GO:0019980 interleukin-5 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019980 IL-5 binding Interacting selectively and non-covalently with interleukin-5. GO:0019981 interleukin-6 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019981 IL-6 binding Interacting selectively and non-covalently with interleukin-6. GO:0005318 obsolete phosphate:hydrogen symporter biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005318 phosphate:hydrogen symporter|phosphate:proton symporter activity OBSOLETE. (Was not defined before being made obsolete). GO:0005319 lipid transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005319 Reactome:R-HSA-8848053|Reactome:R-HSA-8866329|Reactome:R-HSA-5683714|Reactome:R-HSA-5682285|Reactome:R-HSA-6801250|Reactome:R-HSA-174786|Reactome:R-HSA-5683672|Reactome:R-HSA-1369028|Reactome:R-HSA-5688397|Reactome:R-HSA-5682311|Reactome:R-HSA-1369052 apolipoprotein|lipophorin Enables the directed movement of lipids into, out of or within a cell, or between cells. GO:0005316 high-affinity inorganic phosphate:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005316 sodium/phosphate cotransporter activity|high affinity inorganic phosphate:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: HPO42-(out) + Na+(out) = HPO42-(in) + Na+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. CHEBI:149743 N-(fatty acyl)-L-glutamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_149743 GO:0005317 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005317 GO:0005314 high-affinity glutamate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005314 Reactome:R-HSA-5625015|Reactome:R-HSA-5625029|Reactome:R-HSA-428015|Reactome:R-HSA-210404 high-affinity glutamate transporter activity Enables the transfer of glutamate from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. GO:0005315 inorganic phosphate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005315 Enables the transfer of a inorganic phosphate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. GO:0005312 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005312 GO:0005313 L-glutamate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005313 Reactome:R-HSA-5624256|Reactome:R-HSA-210444|Reactome:R-HSA-428052 glutamate/aspartate:sodium symporter activity|L-glutamate transporter activity|glutamate/aspartate porter activity Enables the transfer of L-glutamate from one side of a membrane to the other. L-glutamate is the anion of 2-aminopentanedioic acid. GO:0005310 dicarboxylic acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005310 Reactome:R-HSA-1614546|Reactome:R-HSA-372843 dicarboxylate (succinate/fumarate/malate) antiporter activity|dicarboxylic acid permease activity|dicarboxylate carrier|sodium:dicarboxylate/tricarboxylate symporter activity Enables the transfer of dicarboxylic acids from one side of a membrane to the other. A dicarboxylic acid is an organic acid with two COOH groups. GO:0005311 obsolete sodium:dicarboxylate/tricarboxylate symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005311 sodium:dicarboxylate/tricarboxylate symporter activity|sodium:dicarboxylate/tricarboxylate cotransporter activity OBSOLETE. Catalysis of the reaction: (dicarboxylate or tricarboxylate)(out) + Na+(out) = (dicarboxylate or tricarboxylate)(in) + Na+(in). CHEBI:149741 N-(fatty acyl)-L-isoleucine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_149741 CHEBI:149742 N-(fatty acyl)-glycine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_149742 CHEBI:149740 N-(fatty acyl)-L-leucine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_149740 GO:0019959 interleukin-8 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019959 IL-8 binding Interacting selectively and non-covalently with interleukin-8. GO:0019957 C-C chemokine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019957 Interacting selectively and non-covalently with a C-C chemokine; C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif. GO:0019958 C-X-C chemokine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019958 Interacting selectively and non-covalently with a C-X-C chemokine; C-X-C chemokines have a single amino acid between the first two cysteines of the characteristic four cysteine motif. GO:0019955 cytokine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019955 interleukin binding|IL binding Interacting selectively and non-covalently with a cytokine, any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity. GO:0019956 chemokine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019956 Interacting selectively and non-covalently with a chemokine. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria. GO:0019953 sexual reproduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019953 Wikipedia:Sexual_reproduction A reproduction process that creates a new organism by combining the genetic material of two gametes, which may come from two organisms or from a single organism, in the case of self-fertilizing hermaphrodites, e.g. C. elegans, or self-fertilization in plants. It occurs both in eukaryotes and prokaryotes: in multicellular eukaryotic organisms, an individual is created anew; in prokaryotes, the initial cell has additional or transformed genetic material. In a process called genetic recombination, genetic material (DNA) originating from two gametes join up so that homologous sequences are aligned with each other, and this is followed by exchange of genetic information. After the new recombinant chromosome is formed, it is passed on to progeny. GO:0019954 asexual reproduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019954 Wikipedia:Asexual_reproduction parthenogenesis The biological process in which new individuals are produced by either a single cell or a group of cells, in the absence of any sexual process. GO:0019951 Smt3-protein conjugation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019951 Smt3p-protein conjugation The covalent addition to a protein of Smt3, a ubiquitin-like protein. GO:0019952 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019952 GO:0019950 SMT3-dependent protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019950 SMT3-dependent protein catabolism|SMT3-dependent protein degradation|SMT3-dependent protein breakdown The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by covalent attachment of the ubiquitin-like protein SMT3 to the target protein. GO:0005329 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005329 GO:0005328 neurotransmitter:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005328 sodium/neurotransmitter symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neurotransmitter(out) + Na+(out) = neurotransmitter(in) + Na+(in). GO:0005325 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005325 GO:0005326 neurotransmitter transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005326 Reactome:R-HSA-374896|Reactome:R-HSA-374919 neurotransmitter transporter activity|neurotransmitter transmembrane transporter activity Enables the directed movement of a neurotransmitter into, out of or within a cell, or between cells. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell. GO:0005323 obsolete very-low-density lipoprotein biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005323 very-low-density lipoprotein|VLDL OBSOLETE. (Was not defined before being made obsolete). GO:0005324 long-chain fatty acid transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005324 Reactome:R-HSA-2046093|Reactome:R-HSA-5684043|Reactome:R-HSA-2046087|Reactome:R-HSA-390393|Reactome:R-HSA-434381|Reactome:R-HSA-382575 Enables the transfer of long-chain fatty acids from one side of a membrane to the other. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22. CHEBI:149737 N-(fatty acyl)-L-methionine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_149737 GO:0005321 obsolete high-density lipoprotein biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005321 HDL|high-density lipoprotein OBSOLETE. (Was not defined before being made obsolete). GO:0005322 obsolete low-density lipoprotein biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005322 low-density lipoprotein|LDL OBSOLETE. (Was not defined before being made obsolete). GO:0005320 obsolete apolipoprotein biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005320 apolipoprotein OBSOLETE. (Was not defined before being made obsolete). GO:0019968 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019968 GO:0019969 interleukin-10 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019969 IL-10 binding Interacting selectively and non-covalently with interleukin-10. GO:0019966 interleukin-1 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019966 IL-1 binding Interacting selectively and non-covalently with interleukin-1. GO:0019967 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019967 GO:0019964 interferon-gamma binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019964 IFN-gamma binding|type II interferon binding|IFNG binding Interacting selectively and non-covalently with interferon-gamma. Interferon gamma is the only member of the type II interferon found so far. GO:0019965 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019965 GO:0019962 type I interferon binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019962 interferon-delta binding|interferon-alpha/beta binding|interferon-kappa binding|interferon-epsilon binding|interferon-tau binding|interferon-zeta binding|type I IFN binding|interferon-omega binding|interferon-alpha binding|interferon-beta binding Interacting selectively and non-covalently with a type I interferon. Type I interferons include the interferon-alpha, beta, delta, epsilon, zeta, kappa, tau, and omega gene families. NCBITaxon:6157 Platyhelminthes organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_6157 flatworm|flatworms|flatworms GO:0019963 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019963 GO:0019960 C-X3-C chemokine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019960 Interacting selectively and non-covalently with a C-X3-C chemokine; C-X3-C chemokines have three amino acids between the first two cysteines of the characteristic four-cysteine motif. GO:0019961 interferon binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019961 IFN binding Interacting selectively and non-covalently with an interferon, a protein produced by the immune systems of many animals in response to a challenge by a foreign agent. GO:0019939 peptidyl-S-palmitoleyl-L-cysteine biosynthetic process from peptidyl-cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019939 RESID:AA0308 peptidyl-S-palmitoleyl-L-cysteine anabolism from peptidyl-cysteine|peptidyl-S-palmitoleyl-L-cysteine formation from peptidyl-cysteine|peptidyl-S-palmitoleyl-L-cysteine synthesis from peptidyl-cysteine The modification of peptidyl-cysteine to form peptidyl-S-palmitoleyl-L-cysteine specifically. GO:0019937 protein catenane formation via N6-(L-isoaspartyl)-L-lysine, autocatalytic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019937 RESID:AA0294 The autocatalytic formation of isopeptide bonds by ligation of peptidyl-lysine and peptidyl-asparagine residues; known to occur in the capsid of some bacteriophage, such as HK97, where it is thought to provide a mechanism for stabilizing the capsid. GO:0019938 peptide cross-linking via N6-(L-isoaspartyl)-L-lysine, presumed catalytic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019938 RESID:AA0294 The formation of isopeptide bonds by ligation of peptidyl-lysine and peptidyl-asparagine residues; occurs in mammals in proteins as yet unidentified by a mechanism probably analogous to that of transglutaminase reactions. GO:0019935 cyclic-nucleotide-mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019935 cyclic-nucleotide-mediated signalling Any intracellular signal transduction in which the signal is passed on within the cell via a cyclic nucleotide. Includes production or release of the cyclic nucleotide, and downstream effectors that further transmit the signal within the cell. GO:0019936 obsolete inositol phospholipid-mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019936 inositol phospholipid-mediated signalling|inositol phospholipid-mediated signaling OBSOLETE. (Was not defined before being made obsolete). GO:0019933 cAMP-mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019933 3',5'-cAMP-mediated signalling|adenosine 3',5'-cyclophosphate-mediated signalling|cAMP-mediated signalling|cyclic AMP-mediated signalling|3',5' cAMP-mediated signaling|cAMP signalling|cAMP signaling|3',5' cAMP-mediated signalling|cyclic AMP-mediated signaling|adenosine 3',5'-cyclophosphate-mediated signaling|3',5'-cAMP-mediated signaling|cAMP-mediated signal transduction Any intracellular signal transduction in which the signal is passed on within the cell via cyclic AMP (cAMP). Includes production of cAMP, and downstream effectors that further transmit the signal within the cell. GO:0019934 cGMP-mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019934 cGMP-mediated signalling Any intracellular signal transduction in which the signal is passed on within the cell via cyclic GMP (cGMP). Includes production of cGMP, and downstream effectors that further transmit the signal within the cell. GO:0019931 protein-chromophore linkage via peptidyl-N6-3-dehydroretinal-L-lysine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019931 RESID:AA0312 The modification of peptidyl-lysine to form N6-3,4-didehydroretinylidene-L-lysine. CHEBI:5768 (1E,4E,8E)-alpha-humulene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_5768 GO:0019932 second-messenger-mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019932 second messenger mediated signaling|second-messenger-mediated signalling|second messenger mediated signalling|second messenger-mediated signaling|second-messenger-mediated signal transduction|second messenger-mediated signalling Any intracellular signal transduction in which the signal is passed on within the cell via a second messenger; a small molecule or ion that can be quickly generated or released from intracellular stores, and can diffuse within the cell. Second-messenger signaling includes production or release of the second messenger, and effectors downstream of the second messenger that further transmit the signal within the cell. GO:0019930 cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid peptidyl-aspartate ester biosynthetic process from peptidyl-aspartic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019930 RESID:AA0316 cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid peptidyl-aspartate ester anabolism from peptidyl-aspartic acid|cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid peptidyl-aspartate ester synthesis from peptidyl-aspartic acid|cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid peptidyl-aspartate ester formation from peptidyl-aspartic acid The modification of peptidyl-aspartic acid to form peptidyl-cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid aspartate ester, typical of the barley lipid transfer protein 1. CHEBI:18399 codeinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18399 UBERON:0004103 alveolar ridge biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004103 margo alveolaris|alveolar margin|alveolar bone|alveolar body|alveolar process one of the two jaw ridges either on the roof of the mouth between the upper teeth and the hard palate or on the bottom of the mouth behind the lower teeth[WP]. The alveolar ridges contain the sockets (alveoli) of the teeth[HP]. CHEBI:18397 2-phenylethylamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18397 CHEBI:18398 linear maltodextrin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18398 CHEBI:18396 beta-D-mannosyldiacetylchitobiosyldiphosphodolichol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18396 GO:0005307 choline:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005307 sodium/choline symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: choline(out) + Na+(out) = choline(in) + Na+(in). CHEBI:18393 naphthalene-1,3,8-triol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18393 GO:0005308 creatine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005308 Enables the transfer of creatine from one side of a membrane to the other. Creatine is a compound synthesized from the amino acids arginine, glycine, and methionine that occurs in muscle. CHEBI:18394 6-O-alpha-D-glucopyranosyl-D-fructofuranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18394 CHEBI:18391 D-gluconate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18391 GO:0005306 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005306 CHEBI:18392 bis(beta-glucosyluronic acid)bilirubin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18392 GO:0005304 L-valine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005304 leucine/valine/isoleucine permease activity|valine/tyrosine/tryptophan permease activity|L-valine transporter activity|leucine/isoleucine/valine porter activity|isoleucine/valine:sodium symporter activity Enables the transfer of L-valine from one side of a membrane to the other. L-valine is 2-amino-3-methylbutanoic acid. CHEBI:18390 N-acyl-beta-D-galactosylsphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18390 CHEBI:149714 N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminosyl-(2->6)]-N-acetyl-D-glucosaminide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_149714 GO:0005301 obsolete valine/tyrosine/tryptophan permease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005301 valine/tyrosine/tryptophan permease activity|hydrogen/valine-tyrosine-tryptophan transporter OBSOLETE. (Was not defined before being made obsolete). GO:0005302 L-tyrosine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005302 L-tyrosine permease activity|L-tyrosine transporter activity|valine/tyrosine/tryptophan permease activity Enables the transfer of L-tyrosine from one side of a membrane to the other. L-tyrosine is 2-amino-3-(4-hydroxyphenyl)propanoic acid. GO:0005300 high-affinity tryptophan transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005300 high-affinity tryptophan transporter activity Catalysis of the high-affinity transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. CHEBI:57990 2-dehydro-3-deoxy-D-gluconate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57990 GO:0019948 SUMO activating enzyme activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019948 Reactome:R-HSA-2993784|Reactome:R-HSA-2993781|Reactome:R-HSA-2990833 SMT3 activating enzyme|SUMO E1 activator enzyme Catalysis of the activation of the proteolytically processed small ubiquitin-related modifier SUMO, through the formation of an ATP-dependent high-energy thiolester bond. GO:0019949 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019949 CHEBI:57991 biliverdin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57991 GO:0019946 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019946 GO:0019947 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019947 GO:0019944 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019944 GO:0019945 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019945 GO:0019942 obsolete NEDD8 class-dependent protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019942 NEDD8 class-dependent protein degradation|NEDD8 class-dependent protein breakdown|RUB1-dependent protein degradation|NEDD8 class-dependent protein catabolic process|RUB1-dependent protein catabolism|RUB1-dependent protein catabolic process|NEDD8 class-dependent protein catabolism OBSOLETE. The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by covalent attachment of the ubiquitin-like protein NEDD8 (RUB1) to the target protein. GO:0019943 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019943 GO:0019940 obsolete SUMO-dependent protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019940 SUMO-dependent protein degradation|SUMO-dependent protein breakdown|SUMO-dependent protein catabolic process|SUMO-dependent protein catabolism OBSOLETE. (Was not defined before being made obsolete). CHEBI:57998 3-phosphoglycerate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57998 GO:0019941 modification-dependent protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019941 modification-initiated protein catabolic process|modification-dependent protein breakdown|modification-initiated proteolysis|protein-ligand-dependent protein catabolic process|protein degradation tagging activity|modification-initiated protein catabolism|protein-ligand-dependent protein catabolism|modification-dependent proteolysis|modification-dependent protein catabolism|modification-dependent protein degradation The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent modification of the target protein. CHEBI:57999 1-carboxylatovinyl carboxylatophosphonate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57999 CHEBI:18388 apigenin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18388 CHEBI:57996 nororientalinium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57996 CHEBI:57997 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57997 CHEBI:18386 quinaldic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18386 CHEBI:57994 2,3,5,6-tetrachlorobenzene-1,4-bis(olate) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57994 CHEBI:57995 all-trans-undecaprenyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57995 CHEBI:18387 N-formimidoyl-L-aspartate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18387 GO:0005309 creatine:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005309 Reactome:R-HSA-200396 sodium/chloride-dependent creatine transporter Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: creatine(out) + Na+(out) = creatine(in) + Na+(in). CHEBI:18384 1D-myo-inositol 4-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18384 CHEBI:57992 2-(carboxylatomethoxy)succinate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57992 CHEBI:57993 (S)-N-methylcoclaurinium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57993 CHEBI:18385 thiamine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18385 CHEBI:82904 2-aminophenylglyoxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82904 CHEBI:57989 2-dehydro-3-deoxy-D-galactonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57989 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019919 RESID:AA0069|RESID:AA0068 peptidyl-arginine methylation, to unsymmetrical-dimethyl arginine The process of methylation of peptidyl-arginine to form peptidyl-N(omega),N(omega)-dimethyl-L-arginine. GO:0019917 peptidyl-D-alanine racemization via peptidyl-L-serine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019917 RESID:AA0191 The dehydration of peptidyl-serine, followed by hydrogenation to produce peptidyl-D-alanine. GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019918 RESID:AA0069|RESID:AA0067 The process of methylation of peptidyl-arginine to form peptidyl-N(omega),N'(omega)-dimethyl-L-arginine. GO:0019915 lipid storage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019915 storage of lipids|lipid sequestering|sequestering of lipids|sequestration of lipid|lipid retention|retention of lipids|lipid sequestration|sequestration of lipids The accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development. GO:0019916 peptidyl-D-alanine racemization, direct biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019916 RESID:AA0191 The racemization of peptidyl-alanine. CHEBI:57980 L-histidinol phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57980 GO:0019913 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019913 GO:0019914 cyclin-dependent protein kinase activating kinase regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019914 EC:2.7.1.- cyclin-dependent protein kinase activating kinase, intrinsic regulator activity Modulation of the activity of the enzyme cyclin-dependent protein kinase activating kinase. PATO:0002487 single organismal process quality biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PATO_0002487 A quality inhering in a process by virtue of that process having exactly one organism as a participant. GO:0019911 structural constituent of myelin sheath biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019911 The action of a molecule that contributes to the structural integrity of the myelin sheath of a nerve. GO:0019912 cyclin-dependent protein kinase activating kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019912 cyclin-dependent protein kinase activating kinase, intrinsic catalyst activity|cdk-activating kinase activity|CAK Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; increases the activity of a cyclin-dependent protein kinase (CDK). GO:0019910 mitochondrial pyruvate dehydrogenase (lipoamide) phosphatase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019910 A mitochondrial complex of a regulatory and catalytic subunit that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex. An example of this component is found in Mus musculus. PATO:0002486 multi-organismal process quality biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PATO_0002486 A quality inhering in a process by virtue of that process having two or more organisms as participants. CHEBI:57987 2-hydroxyadipate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57987 CHEBI:57988 allysine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57988 CHEBI:57985 S-inosyl-L-homocysteine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57985 CHEBI:57986 riboflavin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57986 CHEBI:57984 GDP-L-fucose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57984 CHEBI:57981 D-phenylalanine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57981 CHEBI:57982 1-acyl-2-[(S)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57982 CHEBI:82918 hexosyl-(1<->1')-N-acylsphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82918 CHEBI:82919 beta-D-glucosyl-(1<->1')-N-acylsphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82919 CHEBI:57978 2-hydroxy-3-oxopropanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57978 CHEBI:57979 2-(carboxylatomethyl)-5-oxo-2,5-dihydro-2-furoate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57979 FAO:0001030 substrate mycelium biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/FAO_0001030 An invasive mycelium that forms within a solid or semi-solid substrate such as wood, soil or agar. FAO:0001031 aerial mycelium biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/FAO_0001031 A mycelium that forms prior to sporulation and extends aerially, or perpendicular, to its substrate. GO:0019928 peptide cross-linking via 3-(S-L-cysteinyl)-L-aspartic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019928 RESID:AA0314 The cross-linking of a cysteine residue to an aspartic acid residue to form 3-(S-L-cysteinyl)-L-aspartic acid. GO:0019929 peptide cross-linking via 4-(S-L-cysteinyl)-L-glutamic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019929 RESID:AA0315 The cross-linking of a cysteine residue to a glutamic acid residue to form 4-(S-L-cysteinyl)-L-glutamic acid. GO:0019926 peptidyl-tryptophan oxidation to tryptophyl quinone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019926 The oxidation of peptidyl-tryptophan to form tryptophan-6,7-dione, otherwise known as tryptophyl quinone, which is further modified by cross-linking to either tryptophan or cysteine. GO:0019927 peptide cross-linking via 4'-(S-L-cysteinyl)-L-tryptophyl quinone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019927 RESID:AA0313 The cross-linking of a cysteine residue to tryptophyl quinone to form 4'-(S-L-cysteinyl)-L-tryptophyl quinone, a cofactor found at the active site of amine dehydrogenase. GO:0019924 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019924 GO:0019925 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019925 GO:0019922 protein-chromophore linkage via peptidyl-cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019922 The covalent linking of a chromophore to a protein via peptidyl-cysteines. GO:0019923 alpha-1-microglobulin-chromophore linkage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019923 RESID:AA0224 The covalent linking of the alpha-1-microglobulin chromophore to the protein; the structure of the chromophore is not known. It is probably heterogeneous and involving two cysteines in thioether bonds. GO:0019920 peptidyl-1-thioglycine biosynthetic process, internal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019920 RESID:AA0265 peptidyl-1-thioglycine formation, internal|peptidyl-1-thioglycine anabolism, internal|peptidyl-1-thioglycine synthesis, internal The chemical reactions and pathways resulting in the formation of internal peptidyl-1-thioglycine, which has an internal C=S bond, instead of an internal C=O bond, in the peptide. UBERON:0018707 bladder organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018707 bladder A membranous sac in animals that serves as the receptacle of a liquid or contains gas. GO:0019921 peptidyl-1-thioglycine biosynthetic process, carboxy-terminal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019921 RESID:AA0265 peptidyl-1-thioglycine anabolism, carboxy-terminal|peptidyl-1-thioglycine synthesis, carboxy-terminal|peptidyl-1-thioglycine formation, carboxy-terminal The chemical reactions and pathways resulting in the formation of carboxy-terminal peptidyl-1-thioglycine, which has a carboxy-terminal thiocarboxy-C(=O)-SH bond. CHEBI:57976 2-(carboxylatomethyl)-5-oxo-2,5-dihydrofuran-2-ide-3-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57976 CHEBI:57977 bilirubin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57977 CHEBI:57974 O-(3-O-D-galactosyl-N-acetyl-beta-D-galactosaminyl)-L-serine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57974 CHEBI:57975 1-(4-hydroxy-2-methylpyrimid-5-ylmethyl)-3-(2-hydroxyethyl)-2-methylpyridinium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57975 CHEBI:57972 L-alanine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57972 CHEBI:57973 leukotriene C4(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57973 CHEBI:57970 1-acyl-sn-glycerol 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57970 CHEBI:57971 hygromycin B(3+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57971 GO:0030499 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030499 GO:0030490 maturation of SSU-rRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030490 SSU-rRNA maturation|processing of 20S pre-rRNA Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule. GO:0030497 fatty acid elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030497 The elongation of a fatty acid chain by the sequential addition of two-carbon units. GO:0030498 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030498 GO:0030495 bacteriochlorophyll catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030495 bacteriochlorophyll breakdown|bacteriochlorophyll catabolism|bacteriochlorophyll degradation The chemical reactions and pathways resulting in the breakdown of bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. They differ structurally from the chlorophylls of higher plants. GO:0030496 midbody biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0030496 Wikipedia:Midbody_(cell_biology) A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis. GO:0030493 bacteriochlorophyll metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030493 bacteriochlorophyll metabolism The chemical reactions and pathways involving a bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. They differ structurally from the chlorophylls of higher plants. GO:0030494 bacteriochlorophyll biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030494 bacteriochlorophyll biosynthesis|bacteriochlorophyll anabolism|bacteriochlorophyll synthesis|bacteriochlorophyll formation The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. They differ structurally from the chlorophylls of higher plants. GO:0030491 heteroduplex formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030491 The formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules. GO:0030492 hemoglobin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030492 globin binding|haemoglobin binding Interacting selectively and non-covalently with hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin. GO:0030488 tRNA methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030488 The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule. GO:0030489 obsolete processing of 27S pre-rRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030489 processing of 27S pre-rRNA OBSOLETE. (Was not defined before being made obsolete). GO:0030486 smooth muscle dense body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030486 Electron-dense region associated with a smooth muscle contractile fiber. GO:0030487 inositol-4,5-bisphosphate 5-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030487 Catalysis of the reaction: 1D-myo-inositol 4,5-bisphosphate + H2O = 1D-myo-inositol 4-phosphate + phosphate. GO:0030484 obsolete muscle fiber biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030484 muscle fibre|muscle fiber OBSOLETE. The contractile fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle. GO:0030485 smooth muscle contractile fiber biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030485 smooth muscle fiber|smooth muscle fibre The contractile fiber of smooth muscle cells. GO:0030482 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030482 GO:0030483 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030483 GO:0030480 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030480 GO:0030481 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030481 GO:0030479 actin cortical patch biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030479 actin patch An endocytic patch that consists of an actin-containing structure found at the plasma membrane in cells; formed of networks of branched actin filaments that lie just beneath the plasma membrane and assemble, move, and disassemble rapidly. An example of this is the actin cortical patch found in Saccharomyces cerevisiae. GO:0030477 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030477 GO:0030478 actin cap biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030478 Polarized accumulation of cytoskeletal proteins (including F-actin) and regulatory proteins in a cell. An example of this is the actin cap found in Saccharomyces cerevisiae. OBO:GOCHE_71300 substance with EC 2.* (transferase) inhibitor role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_71300 GO:0030475 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030475 GO:0030476 ascospore wall assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030476 spore wall assembly The aggregation, arrangement and bonding together of a set of components to form an ascospore wall. During sporulation in Ascomycota, each ascospore nucleus becomes surrounded by a specialized spore wall, formed by deposition of spore wall components in the lumenal space between the outer and inner leaflets of the prospore membrane. An example of this process is found in Saccharomyces cerevisiae. GO:0030473 nuclear migration along microtubule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030473 transport of nucleus, microtubule-mediated|microtubule-mediated nuclear migration|microtubule cytoskeleton-dependent nuclear positioning|nuclear movement, microtubule-mediated|nucleus migration|nuclear migration, microtubule-mediated|microtubule-dependent nucleus positioning|transport of nucleus by microtubules|microtubule cytoskeleton-dependent nucleus positioning|microtubule-dependent nuclear positioning The directed movement of the nucleus along microtubules within the cell, mediated by motor proteins. GO:0030474 spindle pole body duplication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030474 spindle pole body assembly|spindle pole body duplication in cytoplasm|spindle pole body biogenesis|spindle pole body duplication associated with nuclear envelope|spindle pole body formation|spindle pole body replication|spindle pole body biosynthesis Construction of a new spindle pole body. GO:0030471 obsolete spindle pole body and microtubule cycle (sensu Fungi) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030471 spindle pole body and microtubule cycle (sensu Saccharomyces)|spindle pole body and microtubule cycle (sensu Fungi) OBSOLETE. The dynamics of the spindle pole body and microtubule cytoskeleton during the cell cycle. Includes spindle pole body duplication and separation and formation and elongation of the mitotic spindle. As in, but not restricted to, the fungi (Fungi, ncbi_taxonomy_id:4751). GO:0030472 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030472 GO:0030470 obsolete spore germination (sensu Fungi) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030470 spore germination (sensu Fungi)|germination (sensu Saccharomyces) OBSOLETE. Process of breakdown or opening of the spore-containing structure, modification of the spore wall, and resumption of growth of the spore. As in, but not restricted to, the fungi (Fungi, ncbi_taxonomy_id:4751). GO:0030468 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030468 GO:0030469 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030469 GO:0030466 silent mating-type cassette heterochromatin assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030466 establishment of chromatin silencing at silent mating-type cassette|aging-dependent sterility|heterochromatic silencing at silent mating-type cassette|chromatin silencing at HML and HMR|silent mating-type cassette chromatin silencing|chromatin silencing at silent mating-type cassette Repression of transcription at silent mating-type loci by alteration of the structure of chromatin. GO:0030467 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030467 GO:0030464 obsolete aging dependent sterility (sensu Fungi) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030464 aging dependent sterility (sensu Fungi) OBSOLETE. (Was not defined before being made obsolete). GO:0030465 obsolete autophagic death (sensu Fungi) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030465 autophagic death (sensu Fungi) OBSOLETE. (Was not defined before being made obsolete). GO:0030462 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030462 GO:0030463 obsolete cell aging (sensu Fungi) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030463 cell aging (sensu Fungi) OBSOLETE. (Was not defined before being made obsolete). GO:0030460 obsolete nuclear translocation of MAPK (mating sensu Fungi) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030460 nuclear translocation of MAPK (mating sensu Fungi) OBSOLETE. (Was not defined before being made obsolete). GO:0030461 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030461 GO:0030459 obsolete inactivation of MAPK (mating sensu Fungi) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030459 inactivation of MAPK (mating sensu Fungi) OBSOLETE. (Was not defined before being made obsolete). GO:0030457 obsolete activation of MAPKK (mating sensu Fungi) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030457 activation of MAPKK (mating sensu Fungi) OBSOLETE. (Was not defined before being made obsolete). GO:0030458 obsolete activation of MAPKKK (mating sensu Fungi) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030458 activation of MAPKKK (mating sensu Fungi) OBSOLETE. (Was not defined before being made obsolete). GO:0005499 vitamin D binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005499 ergocalciferol binding|cholecalciferol binding|calciferol binding Interacting selectively and non-covalently with vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3). GO:0030455 obsolete MAPKKK cascade (mating sensu Fungi) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030455 MAPKKK cascade (mating sensu Fungi) OBSOLETE. MAPKKK cascade involved in transducing mating pheromone signal in a fungus. GO:0030456 obsolete activation of MAPK (mating sensu Fungi) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030456 activation of MAPK (mating sensu Fungi) OBSOLETE. (Was not defined before being made obsolete). RO:0002495 immediate transformation of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002495 RO:0002495 immediately transforms from|direct_transformation_of GO:0005497 androgen binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005497 Interacting selectively and non-covalently with any androgen, male sex hormones. RO:0002496 existence starts during or after biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002496 RO:0002496 GO:0005498 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005498 RO:0002497 existence ends during or before biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002497 RO:0002497 CHEBI:140991 omega-methyl-long-chain fatty acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140991 GO:0005496 steroid binding biolink:MolecularActivity go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0005496 Interacting selectively and non-covalently with a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene. CHEBI:140992 omega-hydroxy-long-chain fatty acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140992 RO:0002491 existence starts and ends during biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002491 RO:0002491 RO:0002492 existence ends during biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002492 RO:0002492 ceases_to_exist_during Relation between continuant c and occurrent s, such that every instance of c ceases to exist during some s, if it does not die prematurely. RO:0002493 existence ends with biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002493 RO:0002493 Relation between continuant and occurrent, such that c ceases to exist at the end of p. RO:0002494 transformation of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002494 RO:0002494 transforms from x transformation of y if x is the immediate transformation of y, or is linked to y through a chain of transformation relationships RO:0002488 existence starts during biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002488 RO:0002488 begins_to_exist_during Relation between continuant c and occurrent s, such that every instance of c comes into existing during some s. CHEBI:140997 omega-hydroxy-long-chain fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_140997 RO:0002489 existence starts with biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002489 RO:0002489 Relation between continuant and occurrent, such that c comes into existence at the start of p. GO:0030453 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030453 GO:0030454 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030454 GO:0030451 regulation of complement activation, alternative pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030451 regulation of complement cascade, alternative pathway Any process that modulates the frequency, rate or extent of the alternative pathway of complement activation. GO:0030452 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030452 GO:0030450 regulation of complement activation, classical pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030450 regulation of complement cascade, classical pathway Any process that modulates the frequency, rate or extent of the classical pathway of complement activation. GO:0030448 hyphal growth biolink:BiologicalProcess go-plus goslim_candida http://purl.obolibrary.org/obo/GO_0030448 formation of symbiont invasive hypha within host during symbiotic interaction|symbiont invasive hypha formation within host|formation of symbiont invasive hypha in host|formation of symbiont invasive hypha within host|invasive hyphal growth Growth of fungi as threadlike, tubular structures that may contain multiple nuclei and may or may not be divided internally by septa, or cross-walls. GO:0030449 regulation of complement activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030449 regulation of complement cascade Any process that modulates the frequency, rate or extent of complement activation. GO:0030446 hyphal cell wall biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030446 The cell wall surrounding a fungal hypha. GO:0030447 filamentous growth biolink:BiologicalProcess go-plus goslim_candida|goslim_aspergillus http://purl.obolibrary.org/obo/GO_0030447 The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape. GO:0030444 obsolete microtubule depolymerization during nuclear congression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030444 microtubule depolymerization during nuclear congression OBSOLETE. (Was not defined before being made obsolete). GO:0030445 yeast-form cell wall biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030445 The wall surrounding a cell of a dimorphic fungus growing in the single-cell budding yeast form, in contrast to the filamentous or hyphal form. RO:0002479 has part that occurs in biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002479 RO:0002479 p has part that occurs in c if and only if there exists some p1, such that p has_part p1, and p1 occurs in c. GO:0030442 obsolete inactivation of MAPK during sporulation (sensu Fungi) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030442 inactivation of MAPK during sporulation (sensu Fungi) OBSOLETE. (Was not defined before being made obsolete). GO:0030443 obsolete nuclear translocation of MAPK during sporulation (sensu Fungi) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030443 nuclear translocation of MAPK during sporulation (sensu Fungi) OBSOLETE. (Was not defined before being made obsolete). GO:0030440 obsolete activation of MAPKK during sporulation (sensu Fungi) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030440 activation of MAPKK during sporulation (sensu Fungi) OBSOLETE. (Was not defined before being made obsolete). GO:0030441 obsolete activation of MAPKKK during sporulation (sensu Fungi) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030441 activation of MAPKKK during sporulation (sensu Fungi) OBSOLETE. (Was not defined before being made obsolete). GO:0030439 obsolete activation of MAPK during sporulation (sensu Fungi) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030439 activation of MAPK during sporulation (sensu Fungi) OBSOLETE. (Was not defined before being made obsolete). GO:0030437 ascospore formation biolink:BiologicalProcess go-plus goslim_pombe http://purl.obolibrary.org/obo/GO_0030437 ascospore biosynthesis|sporulation|spore formation The process in which cells that are products of meiosis acquire the specialized features of ascospores. Ascospores are generally found in clusters of four or eight spores within a single mother cell, the ascus, and are characteristic of the ascomycete fungi (phylum Ascomycota). GO:0030438 obsolete MAPKKK cascade during sporulation (sensu Fungi) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030438 MAPKKK cascade during sporulation (sensu Fungi) OBSOLETE. (Was not defined before being made obsolete). CHEBI:149304 L-galactofuranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_149304 GO:0030435 sporulation resulting in formation of a cellular spore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030435 Wikipedia:Sporogenesis spore biosynthesis|cellular spore formation by sporulation|spore formation|spore differentiation The process in which a relatively unspecialized cell acquires the specialized features of a cellular spore, a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction. GO:0005479 obsolete vacuolar assembly biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005479 vacuolar assembly OBSOLETE. (Was not defined before being made obsolete). GO:0030436 asexual sporulation biolink:BiologicalProcess go-plus goslim_aspergillus http://purl.obolibrary.org/obo/GO_0030436 asexual reproductive sporulation|mitotic sporulation|asexual spore formation|mitotic spore formation The formation of spores derived from the products of an asexual cell division. Examples of this process are found in bacteria and fungi. GO:0030433 ubiquitin-dependent ERAD pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030433 endoplasmic reticulum-associated ubiquitin-dependent protein catabolic process|ERAD|endoplasmic reticulum-associated ubiqutin-dependent protein catabolism|ER-associated ubiquitin-dependent protein catabolism|ER-associated ubiquitin-dependent protein catabolic process|ubiquitin-dependent proteasomal protein catabolism of ER proteins|ER-associated ubiquitin-dependent protein degradation|ER-associated ubiquitin-dependent protein breakdown The series of steps necessary to target endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. Begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein ubiquitination necessary for correct substrate transfer, transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome. GO:0005477 pyruvate secondary active transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005477 pyruvate carrier activity Enables the transfer of pyruvate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. GO:0030434 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030434 GO:0005478 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005478 RO:0002473 composed primarily of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002473 RO:0002473 x composed_primarily_of y iff: more than half of the mass of x is made from parts of y GO:0005476 carnitine:acyl carnitine antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005476 carnitine/acyl carnitine carrier activity|fatty acyl carnitine carrier|carnitine:acyl carnitine carrier activity Catalysis of the reaction: carnitine (mitochondrial) + acyl carnitine (cytoplasm) = carnitine (cytoplasm) + acyl carnitine (mitochondrial). GO:0005471 ATP:ADP antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005471 adenine nucleotide translocase|ADP/ATP carrier protein|ADP/ATP translocase|ATP/ADP exchanger|ATP/ADP exchange Catalysis of the reaction: ATP(out) + ADP(in) = ATP(in) + ADP(out). GO:0005472 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005472 GO:0030431 sleep biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0030431 Wikipedia:Sleep dormancy|lethargus|diapause Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain. GO:0030432 peristalsis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030432 Wikipedia:Peristalsis A wavelike sequence of involuntary muscular contraction and relaxation that passes along a tubelike structure, such as the intestine, impelling the contents onwards. CHEBI:5580 gypsogenin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_5580 GO:0030430 host cell cytoplasm biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030430 other organism cytoplasm The cytoplasm of a host cell. CHEBI:5587 sulfurothioic S-acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_5587 GO:0030428 cell septum biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0030428 cross wall|septum A structure composed of peptidoglycan and often chitin in addition to other materials. It usually forms perpendicular to the long axis of a cell or hypha and grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells. GO:0030429 kynureninase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030429 MetaCyc:KYNURENINASE-RXN|RHEA:16813|Reactome:R-HSA-71217|EC:3.7.1.3 kynurenine hydrolase activity|L-kynurenine hydrolase activity Catalysis of the reaction: L-kynurenine + H2O = anthranilate + L-alanine. GO:0030426 growth cone biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030426 Wikipedia:Growth_cone The migrating motile tip of a growing neuron projection, where actin accumulates, and the actin cytoskeleton is the most dynamic. GO:0030427 site of polarized growth biolink:CellularComponent go-plus goslim_candida|goslim_yeast|goslim_pir|goslim_aspergillus http://purl.obolibrary.org/obo/GO_0030427 Any part of a cell where non-isotropic growth takes place. GO:0030424 axon biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030424 Wikipedia:Axon|NIF_Subcellular:sao1770195789 The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter. CHEBI:43291 L-erythro-isocitric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_43291 GO:0030425 dendrite biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030425 NIF_Subcellular:sao1211023249|Wikipedia:Dendrite A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body. GO:0030422 production of siRNA involved in RNA interference biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030422 RNA interference, production of siRNA|production of guide RNAs involved in RNA interference|RNA interference, production of guide RNAs Cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of RNA interference. GO:0005488 binding biolink:MolecularActivity go-plus gocheck_do_not_annotate|goslim_pir|goslim_plant http://purl.obolibrary.org/obo/GO_0005488 Wikipedia:Binding_(molecular) ligand The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. GO:0030423 targeting of mRNA for destruction involved in RNA interference biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030423 RNA interference, targeting of mRNA for destruction The process in which small interfering RNAs target cognate mRNA molecules for degradation. GO:0005489 obsolete electron transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005489 cytochrome c3 (tetraheme)|cytochrome d|class I cytochrome c|class III cytochrome c|cytochrome b|cytochrome b5|cytochrome c554|class II cytochrome c|nonaheme cytochrome c|electron transfer carrier|Rieske iron-sulfur protein|flavodoxin|flavin-containing electron transporter|electron transporter activity|cytochrome c7 (triheme)|class IV cytochrome c|high-molecular-weight cytochrome c (hexadecaheme)|class IIa cytochrome c|monoheme class I cytochrome c|class IIb cytochrome c|respiratory chain cytochrome b6|diheme class I cytochrome c OBSOLETE. Enables the directed movement of electrons into, out of, within or between cells. GO:0005486 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005486 GO:0005487 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005487 GO:0005484 SNAP receptor activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0005484 SNARE|Q-SNARE activity|R-SNARE activity|t-SNARE activity|v-SNARE activity|SNAP-25 Acting as a marker to identify a membrane and interacting selectively with one or more SNAREs on another membrane to mediate membrane fusion. GO:0005485 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005485 GO:0005482 obsolete vesicle targeting biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005482 vesicle targeting OBSOLETE. (Was not defined before being made obsolete). GO:0005483 soluble NSF attachment protein activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005483 SNAP Interacting selectively and non-covalently with both N-ethylmaleimide-sensitive fusion protein (NSF) and a cis-SNARE complex (i.e. a SNARE complex in which all proteins are associated with the same membrane) and increasing the ATPase activity of NSF, thereby allowing ATP hydrolysis by NSF to disassemble the cis-SNARE complex. GO:0005480 obsolete vesicle transport biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005480 vesicle transport OBSOLETE. (Was not defined before being made obsolete). GO:0005481 obsolete vesicle fusion biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005481 vesicle fusion OBSOLETE. (Was not defined before being made obsolete). GO:0005490 obsolete cytochrome P450 biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005490 cytochrome P450 OBSOLETE. A cytochrome b that has a sulfur atom ligated to the iron of the prosthetic group (heme-thiolate); enzymes:typically monooxygenases acting on lipophilic substrates. GO:0030420 establishment of competence for transformation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030420 The process in which a naturally transformable bacterium acquires the ability to take up exogenous DNA. This term should be applied only to naturally transformable bacteria, and should not be used in the context of artificially induced bacterial transformation. GO:0030421 defecation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030421 Wikipedia:Defecation The expulsion of feces from the rectum. CHEBI:67250 secoisolariciresinol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67250 UBERON:0018389 interoceptor biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018389 enteroceptor|visceroceptor A sensory receptor that detects stimulus within the body. Examples of stimuli that would be detected by interoceptors include blood pressure and blood oxygen level. CHEBI:67253 alpha-L-Rhap-(1->3)-alpha-D-GlcpNAc-1-diphospho-trans,octacis-decaprenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67253 CHEBI:33913 corrinoid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33913 CHEBI:33914 aldotriose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33914 CHEBI:33915 aldotetrose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33915 PR:000004140 apolipoprotein A-I biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000004140 APOA1|apolipoprotein A1|ApoA-I|apo-AI A protein that is a translation product of the human APOA1 gene or a 1:1 ortholog thereof. CHEBI:33916 aldopentose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33916 CHEBI:67256 beta-D-Galf-(1->5)-beta-D-Galf-(1->4)-alpha-L-Rhap-(1->3)-alpha-D-GlcpNAc-1-diphospho-trans,octacis-decaprenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67256 CHEBI:33917 aldohexose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33917 RO:0002450 directly positively regulates activity of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002450 RO:0002450 molecularly increases activity of The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B. For example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B. CHEBI:82883 nucleotide 5'-phosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82883 RO:0002448 directly regulates activity of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002448 RO:0002448 molecularly controls The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B. A and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B. PR:000004135 apelin biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000004135 APJ endogenous ligand|APEL|APLN A protein that is a translation product of the human APLN gene or a 1:1 ortholog thereof. RO:0002449 directly negatively regulates activity of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002449 RO:0002449 molecularly decreases activity of The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B. For example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B. CHEBI:82881 N-acylhexadecasphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82881 RO:0002447 phosphorylates biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002447 RO:0002447 CHEBI:67261 (Z)-2,3-dehydroadipyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67261 CHEBI:67262 dihydrocurcumin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67262 CHEBI:67263 tetrahydrocurcumin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67263 CHEBI:67264 geranic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67264 CHEBI:67260 geranate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67260 CHEBI:67269 cyclo(L-leucyl-L-leucyl) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67269 CHEBI:33921 ketoaldohexose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33921 CHEBI:33922 sugar dianhydride biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33922 CHEBI:82897 (S)-miconazole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82897 CHEBI:67265 beta-diketone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67265 CHEBI:33926 dialdose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33926 CHEBI:82894 (R)-miconazole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82894 CHEBI:82891 glucocorticoid receptor antagonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82891 CHEBI:82892 1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82892 RO:0002433 contributes to morphology of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002433 RO:0002433 RO:0002434 interacts with biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002434 RO:0002434 in pairwise interaction with A relationship that holds between two entities in which the processes executed by the two entities are causally connected. RO:0002436 molecularly interacts with biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002436 RO:0002436 An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other. CHEBI:33920 ketoaldose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33920 CHEBI:67273 monohydroxy-1,4-benzoquinones biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67273 CHEBI:67274 lysophosphatidylethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67274 RO:0002430 involved in negative regulation of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002430 RO:0002430 c involved in regulation of p if c is involved in some p' and p' negatively regulates some p RO:0002431 involved in or involved in regulation of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002431 RO:0002431 c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p RO:0002432 is active in biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002432 RO:0002432 enables activity in c executes activity in d if and only if c enables p and p occurs_in d. Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure. RO:0002427 causally downstream of or within biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002427 RO:0002427 inverse of causally upstream of or within RO:0002428 involved in regulation of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002428 RO:0002428 c involved in regulation of p if c is involved in some p' and p' regulates some p RO:0002429 involved in positive regulation of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002429 RO:0002429 c involved in regulation of p if c is involved in some p' and p' positively regulates some p CHEBI:33907 cob(III)yrinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33907 CHEBI:33909 metallotetrapyrrole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33909 CHEBI:33900 tagaturonate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33900 CHEBI:33901 fructuronates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33901 CHEBI:33903 glucuronates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33903 CHEBI:33905 heptose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33905 CHEBI:33906 cobalt corrinoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33906 RO:0002418 causally upstream of or within biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002418 RO:0002418 affects p 'causally upstream or within' q iff (1) the end of p is before the end of q and (2) the execution of p exerts some causal influence over the outputs of q; i.e. if p was abolished or the outputs of p were to be modified, this would necessarily affect q. RO:0002411 causally upstream of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002411 RO:0002411 p is causally upstream of q if and only if p precedes q and p and q are linked in a causal chain RO:0002412 immediately causally upstream of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002412 RO:0002412 p is immediately causally upstream of q iff both (a) p immediately precedes q and (b) p is causally upstream of q. In addition, the output of p must be an input of q. PR:000004126 serum amyloid P-component biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000004126 SAP|APCS|9.5S alpha-1-glycoprotein|PTX2 A protein that is a translation product of the human APCS gene or a 1:1 ortholog thereof. RO:0002410 causally related to biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002410 RO:0002410 This relation groups causal relations between material entities and causal relations between processes RO:0002404 causally downstream of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002404 RO:0002404 inverse of upstream of RO:0002405 immediately causally downstream of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002405 RO:0002405 PR:000004191 androgen receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000004191 dihydrotestosterone receptor|AR|nuclear receptor subfamily 3 group C member 4|DHTR|NR3C4 A protein that is a translation product of the human AR gene or a 1:1 ortholog thereof. PR:000004168 amyloid-beta precursor protein biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000004168 PN-II|cerebral vascular amyloid peptide|A4|alzheimer disease amyloid A4 protein homolog|AD1|APPI|alzheimer disease amyloid protein|AG|amyloid-beta A4 protein|CVAP|ABPP|APP|amyloidogenic glycoprotein|PreA4|protease nexin-II|amyloid beta A4 protein A protein that is a translation product of the human APP gene or a 1:1 ortholog thereof. UBERON:0018391 chemoreceptor biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018391 A sensory receptor that detects chemical stimulus within the body. CHEBI:18240 4-hydroxy-L-proline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18240 CHEBI:57848 1,4-diguanidiniumylbutane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57848 CHEBI:57849 (R)-4-dehydropantoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57849 CHEBI:57846 L-fuculose 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57846 CHEBI:57847 UDP-N-acetyl-D-galactosamine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57847 CHEBI:82803 opine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82803 CHEBI:82800 (R)-cembrene A biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82800 CHEBI:82801 (1S,4E,8E,12E)-2,2,5,9,13-pentamethylcyclopentadeca-4,8,12-trien-1-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82801 CHEBI:33871 glycerate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33871 CHEBI:18239 ditrans,polycis-decaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18239 CHEBI:57844 L-methionine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57844 CHEBI:18236 6-demethylsterigmatocystin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18236 CHEBI:57845 preuroporphyrinogen(8-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57845 CHEBI:18237 glutamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18237 CHEBI:18234 alpha,alpha'-trehalose 6-mycolate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18234 CHEBI:57842 vitexin 2''-O-beta-D-glucoside(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57842 CHEBI:57843 L-selenocysteine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57843 CHEBI:57840 methylguanidinium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57840 CHEBI:18232 D-galactosamine 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18232 CHEBI:57841 4-amino-2-methyl-5-diphosphonatooxymethylpyrimidine(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57841 CHEBI:18233 xyloglucan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18233 CHEBI:18230 chlorophyll a biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18230 CHEBI:18231 arsenic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18231 CHEBI:57839 3-dehydro-2-deoxy-D-gluconate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57839 CHEBI:57837 dTDP-4-dehydro-6-deoxy-D-galactose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57837 CHEBI:82815 3-(methylthio)propanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82815 CHEBI:57838 N-phosphonatotaurocyamine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57838 CHEBI:57835 glutathionylspermidinium(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57835 CHEBI:57836 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate(7-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57836 CHEBI:33888 cobalt molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33888 CHEBI:82811 N-stearoylhexadecasphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82811 CHEBI:82810 N-palmitoylhexadecasphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82810 UBERON:0018415 ethmoid foramen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018415 ethmoid foramina|ethmoidal foramina|foramina ethmoidalia|ethmoidal foramen An bone foramen in the ethmoid bone. UBERON:0018413 facial nerve canal biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018413 fallopian canal|facial canal|canalis nervi facialis A Z-shaped canal running through the temporal bone from the internal acoustic meatus to the stylomastoid foramen. It is located within the middle ear region, according to its shape it is divided into three main segments: the labyrinthine, the tympanic, and the mastoidal segment . CHEBI:33883 fructuronic acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33883 CHEBI:18229 deacetoxycephalosporin C biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18229 CHEBI:33885 alpha-D-galacturonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33885 CHEBI:18227 sterigmatocystin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18227 CHEBI:33886 glucuronic acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33886 CHEBI:18228 1D-myo-inositol 1,3,4-trisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18228 CHEBI:57833 N-benzoyl-4-hydroxyanthranilate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57833 CHEBI:18225 myo-inositol 1,3-bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18225 CHEBI:57834 spermidine(3+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57834 CHEBI:18226 (R)-6-hydroxynicotine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18226 CHEBI:57831 glycerol 1,2-cyclic phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57831 CHEBI:57832 1,2-diacyl-3-[3-(alpha-D-N-acetylneuraminyl)-beta-D-galactosyl]-sn-glycerol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57832 CHEBI:18224 isoeugenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18224 CHEBI:57830 cyanidin 3-O-rutinoside 5-O-beta-D-glucoside betaine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57830 CHEBI:18222 xylose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18222 CHEBI:18220 isoflavone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18220 CHEBI:18261 N-carbamoyl-beta-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18261 CHEBI:18262 dodecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18262 CHEBI:57828 D-hamamelose 2(1)-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57828 CHEBI:82828 oleanolate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82828 CHEBI:82829 sphinganine-based sphingolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82829 CHEBI:57829 L-xylulose 5-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57829 CHEBI:57826 6-aminohexanoic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57826 CHEBI:82827 oleanolic aldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82827 CHEBI:57824 oxalurate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57824 CHEBI:57825 L-lombricine dizwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57825 CHEBI:33855 arenecarbaldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33855 CHEBI:33856 aromatic amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33856 CHEBI:33857 aromatic primary alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33857 CHEBI:33859 aromatic carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33859 CHEBI:33853 phenols biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33853 CHEBI:33854 aromatic alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33854 CHEBI:57822 D-alanyl-D-alanine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57822 CHEBI:18258 3,3',5-triiodo-L-thyronine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18258 CHEBI:18259 N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18259 CHEBI:57823 4-CDP-2-C-methyl-D-erythritol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57823 CHEBI:57820 N(6)-hydroxy-L-lysine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57820 CHEBI:18256 4-formylbenzenesulfonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18256 CHEBI:18257 ornithine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18257 CHEBI:18254 ribonucleoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18254 CHEBI:18255 nebularine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18255 CHEBI:18252 zymosterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18252 CHEBI:18253 5-guanidino-2-oxopentanoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18253 CHEBI:57819 quinolin-4(1H)-one-3-olate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_57819 CHEBI:18250 chondroitin 4'-sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18250 CHEBI:18251 UDP-D-galactofuranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18251 CHEBI:57817 sphinganine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57817 CHEBI:82839 1-oleoyl-2-palmitoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82839 CHEBI:57818 5,10-methylenetetrahydromethanopterin(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57818 CHEBI:82837 1-oleoyl-2-palmitoleoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82837 CHEBI:57815 luteolin 7-O-[(beta-D-glucosiduronate)-(1->2)-(beta-D-glucosiduronate)] biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_57815 CHEBI:57813 quercetin 3,3',7-trissulfate(3-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_57813 CHEBI:57814 triacetate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57814 CHEBI:82836 (9Z)-hexacosenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82836 CHEBI:82833 7-aminomethyl-7-carbaguanine 5'-phosphate zwitterion residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82833 CHEBI:33866 mannonates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33866 CHEBI:67204 carboxynorspermidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67204 CHEBI:82834 epoxyqueuosine 5'-phosphate zwitterion residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82834 CHEBI:33867 idonates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33867 CHEBI:67205 (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67205 CHEBI:82831 queuosine 5'-phosphate zwitterion residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82831 CHEBI:33868 altronates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33868 CHEBI:33869 ribonates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33869 CHEBI:82830 sphingosine-based sphingolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82830 CHEBI:67200 provitamin A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67200 CHEBI:67201 synthetic cannabinoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67201 CHEBI:33860 aromatic amine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33860 CHEBI:33861 transition element coordination entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33861 CHEBI:33862 platinum coordination entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33862 CHEBI:67208 double-stranded RNA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67208 CHEBI:67209 alpha-L-Rhap-(1->3)-alpha-D-GlcpNAc-1-diphospho-trans,octacis-decaprenol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67209 CHEBI:18249 ergosta-5,7,22,24(28)-tetraen-3beta-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18249 CHEBI:33864 gulonates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33864 CHEBI:33865 rhamnonates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33865 CHEBI:57811 sym-homospermidinium(3+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57811 CHEBI:18247 5-amino-6-(5-phospho-D-ribitylamino)uracil biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18247 CHEBI:57812 CMP-N-acetyl-beta-neuraminate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57812 CHEBI:18248 iron atom biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18248 CHEBI:57810 UDP-4-dehydro-6-deoxy-D-glucose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57810 CHEBI:18246 (1->4)-beta-D-glucan biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18246 CHEBI:18243 dopamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18243 CHEBI:18244 1-alkyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18244 CHEBI:18241 2'-deoxyribonucleoside 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18241 CHEBI:18242 cis-5,6-dihydroxy-4-isopropylcyclohexa-1,3-dienecarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18242 CHEBI:57808 xanthommatin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57808 CHEBI:57809 N-formyl-L-methioninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57809 CHEBI:57806 UDP-N-acetyl-D-galactosamine 4,6-bissulfate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57806 CHEBI:57807 UDP-2-acetamido-4-amino-2,4,6-trideoxy-D-glucose(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57807 CHEBI:82848 1,2-dioleoyl-sn-glycero-3-phospho-(1'-sn-glycerol-3'-phosphate) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82848 CHEBI:57804 L-serine phosphoethanolamine dizwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57804 CHEBI:57805 N(2)-acetyl-L-ornithine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57805 CHEBI:82849 1,2-dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-5'-phosphate) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82849 CHEBI:57803 L-tryptophanamide(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57803 CHEBI:33833 heteroarene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33833 CHEBI:67214 2'-deamino-2'-hydroxy-6'-dehydroparomamine(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67214 CHEBI:82844 UDP-2-acetamido-2-deoxy-3-dehydro-alpha-D-glucopyranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82844 CHEBI:82845 UDP-2,3-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82845 CHEBI:33835 anthrone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33835 CHEBI:82842 N-octanoylphytosphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82842 CHEBI:33836 benzenoid aromatic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33836 CHEBI:82840 1-oleoyl-2-myristoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82840 CHEBI:67210 beta-D-Galf-(1->5)-beta-D-Galf-(1->4)-alpha-L-Rhap-(1->3)-alpha-D-GlcpNAc-1-diphospho-trans,octacis-decaprenol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67210 CHEBI:33837 conjugated protein biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33837 CHEBI:82841 N-octanoyldihydrosphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82841 CHEBI:67211 beta-D-Galf-(1->4)-alpha-L-Rhap-(1->3)-alpha-D-GlcpNAc-1-diphospho-trans,octacis-decaprenol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67211 CHEBI:33838 nucleoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33838 CHEBI:67212 [beta-D-Galf-(1->5)-beta-D-Galf-(1->6)]14-beta-D-Galf-(1->5)-beta-D-Galf-(1->4)-alpha-L-Rhap-(1->3)-alpha-D-GlcpNAc-1-diphospho-trans,octacis-decaprenol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67212 CHEBI:33839 macromolecule biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33839 CHEBI:67213 2'-deamino-2'-hydroxyneamine(3+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67213 CHEBI:33830 galacturonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33830 CHEBI:33832 organic cyclic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33832 CHEBI:57800 3-ADP-glycerate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57800 CHEBI:57801 cyclotriphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57801 CHEBI:67225 2'-deamino-2'-hydroxy-6'-dehydroparomamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67225 CHEBI:33845 xylonic acid derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33845 CHEBI:67227 beta-carotene 15,15'-epoxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67227 CHEBI:67228 15,15'-dihydroxy-beta-carotene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67228 CHEBI:33847 monocyclic arene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33847 CHEBI:33848 polycyclic arene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33848 CHEBI:82852 inosine 5'-phosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82852 CHEBI:67223 2'-deamino-2'-hydroxyneamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67223 CHEBI:82850 7-cyano-7-carbaguanine 5'-phosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82850 CHEBI:33842 aromatic annulene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33842 CHEBI:33843 arabinonic acid derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33843 PR:000018721 tumor necrosis factor ligand superfamily member 11 proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000018721 TNFSF11/ClvPrd A tumor necrosis factor ligand superfamily member 11 that has been processed by proteolytic cleavage. CHEBI:82869 (24S)-24-hydroxycholesterol ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82869 CHEBI:67237 (22R)-22-hydroxycholesterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67237 CHEBI:33812 galacturonates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33812 CHEBI:67239 EC 3.2.1.20 (alpha-glucosidase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67239 CHEBI:18218 2'-hydroxybiphenyl-2-sulfinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18218 CHEBI:18216 alpha-N-acetylneuraminosyl-(2->3)-[beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphingosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18216 CHEBI:18217 alpha-D-Gal-(1->3)-beta-D-Gal-(1->4)-D-GlcNAc biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18217 CHEBI:18215 syringetin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18215 CHEBI:18212 selenite(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18212 CHEBI:18210 hyponitrite(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18210 CHEBI:18211 citrulline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18211 CHEBI:67241 beta-D-Galf-(1->4)-alpha-L-Rhap-(1->3)-alpha-D-GlcpNAc-1-diphospho-trans,octacis-decaprenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67241 PR:000018718 C-C motif chemokine 5 proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000018718 CCL5/ClvPrd A C-C motif chemokine 5 that has been processed by proteolytic cleavage. CHEBI:67247 (+)-secoisolariciresinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67247 CHEBI:33822 organic hydroxy compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33822 CHEBI:67248 4-(3-methylbut-2-enyl)-L-abrine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67248 CHEBI:33823 enol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33823 CHEBI:82875 (24S)-24-hydroxycholesterol 3-linoleoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82875 CHEBI:67244 (-)-lariciresinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67244 CHEBI:67245 (-)-pinoresinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67245 CHEBI:33828 xylonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33828 CHEBI:67246 (+)-lariciresinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67246 CHEBI:18209 CoM-S-S-CoB biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18209 CHEBI:18207 N-acetyl-D-galactosamine 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18207 CHEBI:18208 benzylpenicillin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18208 CHEBI:18205 alpha-D-mannose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18205 CHEBI:33820 iduronate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33820 CHEBI:18206 2-amino-5-oxocyclohex-1-enecarbonyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18206 CHEBI:33821 mannuronate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33821 CHEBI:18203 penicillin N biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18203 CHEBI:18204 16,17-didehydroprogesterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18204 CHEBI:18202 L-iditol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18202 CHEBI:18200 isoscoparin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18200 GO:0030417 nicotianamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030417 nicotianamine metabolism The chemical reactions and pathways involving nicotianamine, 2(S),3'2(S),3''(S)-N-(N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl)-azetidine-2-carboxylic acid. GO:0030418 nicotianamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030418 nicotianamine anabolism|nicotianamine biosynthesis|nicotianamine synthesis|nicotianamine formation The chemical reactions and pathways resulting in the formation of nicotianamine, 2(S),3'2(S),3''(S)-N-(N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl)-azetidine-2-carboxylic acid. GO:0005459 UDP-galactose transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005459 Reactome:R-HSA-735702|Reactome:R-HSA-5652099 Enables the transfer of a UDP-galactose from one side of a membrane to the other. UDP-galactose is a substance composed of galactose in glycosidic linkage with uridine diphosphate. GO:0030415 obsolete carboxypeptidase A inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030415 carboxypeptidase A inhibitor activity OBSOLETE. Stops, prevents or reduces the activity of the enzyme carboxypeptidase A. GO:0030416 methylamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030416 methylammonium metabolism|methylammonium metabolic process|methylamine metabolism The chemical reactions and pathways involving methylamine (CH3NH2). GO:0005457 GDP-fucose transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005457 Reactome:R-HSA-742345|Reactome:R-HSA-5653596 Enables the transfer of a GDP-fucose from one side of a membrane to the other. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate. GO:0030413 competence pheromone activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030413 A small peptide excreted by a naturally transformable bacterium (e.g. Bacillus subtilis) that transmits a signal required for the establishment of competence. GO:0005458 GDP-mannose transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005458 Enables the transfer of a GDP-mannose from one side of a membrane to the other. GDP-mannose is a substance composed of mannose in glycosidic linkage with guanosine diphosphate. GO:0030414 peptidase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030414 protease inhibitor activity Stops, prevents or reduces the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds. GO:0030411 scytalone dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030411 EC:4.2.1.94|RHEA:24396|KEGG_REACTION:R02907|MetaCyc:SCYTALONE-DEHYDRATASE-RXN scytalone 7,8-hydro-lyase activity|scytalone 7,8-hydro-lyase (1,3,8-trihydroxynaphthalene-forming) Catalysis of the reaction: scytalone = 1,3,8-trihydroxynaphthalene + H(2)O. GO:0030412 formimidoyltetrahydrofolate cyclodeaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030412 EC:4.3.1.4|Reactome:R-HSA-70920|RHEA:22736|KEGG_REACTION:R02302|MetaCyc:4.3.1.4-RXN 5-formimidoyltetrahydrofolate ammonia-lyase (cyclizing)|5-formimidoyltetrahydrofolate ammonia-lyase (cyclizing; 5,10-methenyltetrahydrofolate-forming)|formiminotetrahydrofolate cyclodeaminase activity Catalysis of the reaction: 5-formimidoyltetrahydrofolate + 2 H(+) = 5,10-methenyltetrahydrofolate + NH(4)(+). GO:0005456 CMP-N-acetylneuraminate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005456 Reactome:R-HSA-727807|Reactome:R-HSA-5651942 CMP-sialic acid transmembrane transporter activity Enables the transfer of a CMP-N-acetylneuraminate from one side of a membrane to the other. GO:0005453 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005453 GO:0005454 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005454 GO:0005451 monovalent cation:proton antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005451 Reactome:R-HSA-2889070 monovalent cation:hydrogen antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monovalent cation(out) + H+(in) = monovalent cation(in) + H+(out). GO:0005452 inorganic anion exchanger activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005452 Reactome:R-HSA-425577|Reactome:R-HSA-427666|Reactome:R-HSA-425482|Reactome:R-HSA-5656248|Reactome:R-HSA-5627737|Reactome:R-HSA-1247665|Reactome:R-HSA-1237038 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: inorganic anion A(out) + inorganic anion B(in) = inorganic anion A(in) + inorganic anion B(out). GO:0030419 nicotianamine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030419 nicotianamine breakdown|nicotianamine catabolism|nicotianamine degradation The chemical reactions and pathways resulting in the breakdown of nicotianamine, 2(S),3'2(S),3''(S)-N-(N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl)-azetidine-2-carboxylic acid. GO:0030410 nicotianamine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030410 KEGG_REACTION:R00075|RHEA:16481|MetaCyc:2.5.1.43-RXN|EC:2.5.1.43 S-adenosyl-L-methionine:S-adenosyl-L-methionine:S-adenosyl-L-methionine 3-amino-3-carboxypropyltransferase activity Catalysis of the reaction: 3 S-adenosyl-L-methionine(1+) = 3 S-methyl-5'-thioadenosine + 3 H(+) + nicotianamine. GO:0030406 obsolete matrix metalloproteinase 25 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030406 MT6-MMP|matrix metalloproteinase 25 activity|MMP-25 OBSOLETE. Was not defined before being made obsolete. GO:0030407 formimidoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030407 formiminotransferase activity Catalysis of the transfer of a formimino group from 5-formimidoyltetrahydrofolate to an acceptor molecule such as an amino acid. GO:0030404 obsolete collagenase 3 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030404 matrix metalloproteinase 13|collagenase 3 activity|MMP-13 OBSOLETE. Was not defined before being made obsolete. GO:0030405 obsolete matrix metalloproteinase 19 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030405 MMP-19|matrix metalloproteinase 19 activity OBSOLETE. Was not defined before being made obsolete. GO:0005468 obsolete small-molecule carrier or transporter biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005468 small-molecule carrier or transporter OBSOLETE. (Was not defined before being made obsolete). GO:0030402 obsolete matrilysin-2 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030402 matrilysin-2 activity|matrix metalloproteinase 26|MMP-26 OBSOLETE. Was not defined before being made obsolete. GO:0005469 succinate:fumarate antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005469 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: succinate(out) + fumarate(in) = succinate(in) + fumarate(out). GO:0030403 obsolete collagenase 4 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030403 matrix metalloproteinase 18|MMP-18|collagenase 4 activity OBSOLETE. Was not defined before being made obsolete. GO:0030400 obsolete protease substrate recruitment factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030400 protease substrate recruitment factor activity OBSOLETE. A recruiting factor or adaptor molecule associated with the proteasome that activates degradation of specific proteasomal substrates and links them to the degradation machinery; it is not involved in ubiquitination; does not possess proteolytic activity. GO:0030401 obsolete transcription antiterminator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030401 transcription antiterminator activity|transcriptional antiterminator activity OBSOLETE. Functions to prevent the termination of RNA synthesis. Acts as a regulatory device, e.g. in phage lambda, enabling a terminator to be masked from RNA polymerase so that distal genes can be expressed. GO:0005464 UDP-xylose transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005464 Reactome:R-HSA-742373 Enables the transfer of UDP-xylose from one side of a membrane to the other. UDP-xylose is a substance composed of xylose in glycosidic linkage with uridine diphosphate. GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005462 Reactome:R-HSA-5653622|Reactome:R-HSA-741450|Reactome:R-HSA-742354 Enables the transfer of a UDP-N-acetylglucosamine from one side of a membrane to the other. N-acetylglucosamine is a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate. GO:0005463 UDP-N-acetylgalactosamine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005463 Enables the transfer of a N-acetylgalactosamine from one side of a membrane to the other. N-acetylgalactosamine is a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate. GO:0005460 UDP-glucose transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005460 Enables the transfer of a UDP-glucose from one side of a membrane to the other. UDP-glucose is a substance composed of glucose in glycosidic linkage with uridine diphosphate. GO:0005461 UDP-glucuronic acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005461 Reactome:R-HSA-174368|Reactome:R-HSA-5603297 Enables the transfer of a UDP-glucuronic acid from one side of a membrane to the other. UDP-glucuronic acid is a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate. GO:0030408 glycine formimidoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030408 KEGG_REACTION:R02729|MetaCyc:GLYCINE-FORMIMINOTRANSFERASE-RXN|RHEA:24288|EC:2.1.2.4 5-formimidoyltetrahydrofolate:glycine N-formimidoyltransferase activity|glycine formiminotransferase activity|FIG formiminotransferase activity|formiminoglycine formiminotransferase activity Catalysis of the reaction: 5-formimidoyltetrahydrofolate + glycine = (6S)-5,6,7,8-tetrahydrofolate + N-formimidoylglycine. GO:0030409 glutamate formimidoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030409 MetaCyc:GLUTAMATE-FORMIMINOTRANSFERASE-RXN|EC:2.1.2.5|RHEA:15097 formiminoglutamic acid transferase activity|formiminoglutamic formiminotransferase activity|glutamate formiminotransferase activity|5-formimidoyltetrahydrofolate:L-glutamate N-formimidoyltransferase activity|glutamate formyltransferase activity Catalysis of the reaction: 5-formimidoyltetrahydrofolate + L-glutamate = tetrahydrofolate + N-formimidoyl-L-glutamate. CHEBI:5613 haloperidol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_5613 CHEBI:5610 haloalkene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_5610 GO:0005436 sodium:phosphate symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005436 Reactome:R-HSA-427656|Reactome:R-HSA-2872498|Reactome:R-HSA-5625123|Reactome:R-HSA-428609|Reactome:R-HSA-5687585|Reactome:R-HSA-427645|Reactome:R-HSA-5651685|Reactome:R-HSA-5651697|Reactome:R-HSA-5651971|Reactome:R-HSA-427605 sodium/phosphate symporter activity|sodium-dependent phosphate transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + phosphate(out) = Na+(in) + phosphate(in). GO:0005432 calcium:sodium antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005432 Reactome:R-HSA-8949688|Reactome:R-HSA-8949703|Reactome:R-HSA-425661|RHEA:29255 sodium:calcium exchange|mitochondrial sodium/calcium ion exchange|sodium/calcium exchanger Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + Na+(out) = Ca2+(out) + Na+(in). GO:0005430 obsolete synaptic vesicle amine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005430 OBSOLETE. Enables the transfer of amines across synaptic vesicle membranes. CHEBI:43254 (4S)-4-hydroxy-3,4-dihydropyrimidin-2(1H)-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_43254 CHEBI:57891 trans-2-chloro-4-carboxylatomethylenebut-2-en-1,4-olide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57891 CHEBI:57892 3-(dioxido-lambda(5)-azanylidene)propanoate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_57892 CHEBI:57890 adenosine 5'-phosphoramidate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57890 CHEBI:57899 15,16-dihydrobiliverdin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57899 CHEBI:57897 1-phosphonato-alpha-D-glucuronate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57897 CHEBI:57895 1D-myo-inositol 1,3,4,5-tetrakisphosphate(8-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57895 CHEBI:57896 diisopropyl phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57896 CHEBI:57893 tabersoninium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57893 CHEBI:57894 berbamuninium(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57894 CHEBI:18283 alpha,alpha-trehalose 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18283 CHEBI:18284 thiamine(1+) triphosphate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18284 GO:0005415 nucleoside:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005415 Reactome:R-HSA-109530|Reactome:R-HSA-109538|Reactome:R-HSA-109539 sodium-dependent nucleoside transporter activity|nucleoside-sodium cotransporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nucleoside(out) + Na+(out) = nucleoside(in) + Na+(in). CHEBI:18281 2,5-didehydro-D-gluconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18281 GO:0005416 amino acid:cation symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005416 cation/amino acid symporter activity|cation:amino acid symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + cation(out) = amino acid(in) + cation(in). CHEBI:18282 nucleobase biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18282 CHEBI:18280 phenylglyoxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18280 GO:0005412 glucose:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005412 Reactome:R-HSA-189208|Reactome:R-HSA-5656356|Reactome:R-HSA-8932955|Reactome:R-HSA-429613|Reactome:R-HSA-5658163 sodium/glucose symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in). CHEBI:57880 1-phosphatidyl-1D-myo-inositol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57880 CHEBI:57888 4-carboxylatomethyl-4-methylbut-2-en-1,4-olide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57888 CHEBI:57889 N(5)-(L-1-carboxyethyl)-L-ornithine dizwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57889 CHEBI:57886 2'-deoxy-5-methyl-5'-cytidylate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57886 CHEBI:18278 N-acetyl-D-glucosaminyldiphosphodolichol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18278 CHEBI:57887 tryptaminium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57887 CHEBI:18276 dihydrogen biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18276 CHEBI:57885 3-dehydrocarnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57885 CHEBI:18277 N-(5-phosphonato-beta-D-ribosyl)anthranilate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18277 CHEBI:18274 2'-deoxyribonucleoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18274 CHEBI:57882 erythro-5-phosphonatoooxy-L-lysinium(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57882 CHEBI:57883 4-carboxylatomethyl-3-methylbut-2-en-1,4-olide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57883 CHEBI:18272 N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18272 GO:0005429 obsolete chromaffin granule amine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005429 OBSOLETE. Enables the transfer of amines across chromaffin granule membranes. GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005427 proton-dependent oligopeptide transporter activity|hydrogen/oligopeptide symporter Enables the transfer of a oligopeptide from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by proton movement. CHEBI:18271 2',3'-cyclic nucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18271 CHEBI:57879 4-methylene-L-glutamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57879 OBA:VT0001614 blood vessel morphology trait biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_VT0001614 morphology of blood vessel The morphology of a blood vessel. CHEBI:57870 D-ribulose 1,5-bisphosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57870 CHEBI:57877 N-acetyl-D-tryptophanate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57877 CHEBI:18269 (1->6)-alpha-D-glucan biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18269 CHEBI:57878 2-acetamido-2-deoxy-3-O-(4-deoxy-alpha-L-threo-hex-4-enopyranosyluronate)-6-O-sulfonato-D-galactopyranose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57878 CHEBI:18267 5-oxo-4,5-dihydro-2-furylacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18267 CHEBI:57875 2-acyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57875 CHEBI:57876 CDP-ethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57876 CHEBI:18268 D-glucurono-6,3-lactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18268 CHEBI:18265 2-aminopteridin-4-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18265 CHEBI:57873 (S)-reticulinium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57873 CHEBI:5653 hemiacetal biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_5653 CHEBI:18266 1D-4-O-methyl-myo-inositol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18266 CHEBI:18263 1-(5-phospho-D-ribosyl)-ATP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18263 CHEBI:57871 codeine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57871 CHEBI:57872 (Z)-but-2-ene-1,2,3-tricarboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57872 CHEBI:57868 N-sulfo-D-glucosamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57868 CHEBI:57869 6-aminopenicillanic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57869 CHEBI:33899 tagaturonic acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33899 CHEBI:33892 iron coordination entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33892 CHEBI:33893 reagent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33893 CHEBI:33897 iduronic acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33897 CHEBI:33898 mannuronic acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33898 CHEBI:57866 3-methylthiopropylaminium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57866 CHEBI:57867 nucleoside 5'-phosphate dianion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57867 CHEBI:57864 (4S,5S)-5-hydroxy-4-(hydroxymethyl)-6-oxocyclohex-1-en-1-olate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_57864 CHEBI:57865 uridine 5'-monophosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57865 CHEBI:18298 3-hydroxy-2-methyl-3-phytyl-2,3-dihydro-1,4-naphthoquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18298 CHEBI:57862 diphthamide(2+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57862 CHEBI:57863 ADP-D-glycero-D-manno-heptose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57863 CHEBI:18299 1-C-(indol-3-yl)glycerol 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18299 CHEBI:18296 chondroitin 6'-sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18296 CHEBI:18297 1D-myo-inositol 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18297 CHEBI:57861 dethiobiotin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57861 CHEBI:33890 cobalt coordination entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33890 CHEBI:18295 histamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18295 CHEBI:18292 jasmonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18292 CHEBI:18293 5-methoxypsoralen biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18293 CHEBI:57859 5-(3-carboxylato-3-oxoprop-1-en-1-yl)-4,6-dihydroxypyridine-2-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57859 GO:0005402 carbohydrate:cation symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005402 cation:sugar symporter activity|sugar:cation symporter activity|cation/sugar symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sugar(out) + cation(out) = sugar(in) + cation(in). CHEBI:18291 manganese atom biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18291 GO:0005403 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005403 CHEBI:57857 N-acetyl-beta-alaninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57857 GO:0005400 obsolete peroxisomal membrane transporter biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005400 peroxisomal membrane transporter OBSOLETE. (Was not defined before being made obsolete). CHEBI:57858 atropinium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57858 CHEBI:57855 protochlorophyllide(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_57855 CHEBI:57856 S-adenosyl-L-homocysteine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57856 CHEBI:57853 hypotaurine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57853 CHEBI:18289 quinolin-2(1H)-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18289 CHEBI:57854 4-guanidiniumylbutanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57854 CHEBI:57851 tropiniumone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57851 CHEBI:18287 L-fucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18287 CHEBI:57852 prephenate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57852 CHEBI:18288 (S)-2-hydroxypropyl-CoM biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18288 CHEBI:18285 (S)-stylopine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18285 CHEBI:57850 3-O-(4-deoxy-alpha-L-threo-hex-4-enopyranosyluronate)-D-galactosamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57850 CHEBI:149484 chloroquine(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_149484 CHEBI:5445 glyceraldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_5445 NCBITaxon:1476529 Cyclostomata organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_1476529 Agnatha|jawless vertebrates CHEBI:5457 glycerophosphoglycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_5457 GO:0030598 rRNA N-glycosylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030598 EC:3.2.2.22|MetaCyc:3.2.2.22-RXN gelonin|ricin|mirabilis antiviral protein|nigrin b|rRNA N-glycohydrolase activity|momorcochin-S|saporins|RNA N-glycosidase activity|ribosomal ribonucleate N-glycosidase activity|rRNA N-glycosidase activity Catalysis of the hydrolysis of the N-glycosylic bond at A-4324 in 28S rRNA from rat ribosomes or corresponding sites in 28S RNA from other species. GO:0030599 pectinesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030599 EC:3.1.1.11|RHEA:22380|MetaCyc:PECTINESTERASE-RXN pectinoesterase activity|pectin pectylhydrolase activity|pectin methyl esterase activity|pectase activity|pectin methylesterase activity|pectin demethoxylase activity|pectin methoxylase activity Catalysis of the reaction: pectin + n H2O = n methanol + pectate. CHEBI:149465 glucopentaose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_149465 GO:0030596 alpha-L-rhamnosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030596 EC:3.2.1.40|MetaCyc:3.2.1.40-RXN alpha-L-rhamnoside rhamnohydrolase activity|alpha-L-rhamnosidase T|alpha-L-rhamnosidase N Catalysis of the hydrolysis of terminal non-reducing alpha-L-rhamnose residues in alpha-L-rhamnosides. GO:0030597 RNA glycosylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030597 Catalysis of the hydrolysis of N-glycosidic bonds in an RNA molecule. GO:0030594 neurotransmitter receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030594 Combining with a neurotransmitter and transmitting the signal to initiate a change in cell activity. GO:0030595 leukocyte chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030595 leucocyte chemotaxis|immune cell chemotaxis The movement of a leukocyte in response to an external stimulus. GO:0030592 DNA ADP-ribosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030592 The covalent attachment of an ADP-ribosyl group to a residue in double-stranded DNA. GO:0030593 neutrophil chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030593 The directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding. GO:0030590 first cell cycle pseudocleavage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030590 A process that occurs during the first cell cycle in an embryo, in which anterior cortical contractions culminate in a single partial constriction of the embryo called the pseudocleavage furrow. An example of this process is found in nematode worms. GO:0030591 2'-deoxyguanosine DNA ADP-ribosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030591 NAD DNA ADP-ribosyltransferase activity Catalysis of the transfer of the ADP-ribose group of NAD+ to the amino group at N2 of 2'-deoxyguanosine to yield N2-(alpha-ADP-ribos-1-yl)-2'-deoxyguanosine and its beta form. GO:0030589 pseudocleavage involved in syncytial blastoderm formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030589 pseudocleavage during syncytial blastoderm formation Formation of furrows in the cytoplasm between nuclei during cell cycles in embryos that contribute to the formation of the syncytial blastoderm. An example of this process is found in Drosophila melanogaster. GO:0030587 sorocarp development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030587 fruiting body development|fruiting body formation|sorocarp biosynthesis|sorocarp formation The process whose specific outcome is the progression of the sorocarp over time, from its formation to the mature structure. The process begins with the aggregation of individual cells and ends with the mature sorocarp. The sorocarp is a structure containing a spore-bearing sorus that sits on top of a stalk. An example of this process is found in Dictyostelium discoideum. GO:0030588 pseudocleavage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030588 Partial constriction of the cytoplasm of a cell to form a furrow that resembles a cleavage furrow but does not complete cytokinesis. CHEBI:5435 piperidine-2,6-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_5435 GO:0030585 phosphoenolpyruvate carboxykinase (diphosphate) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030585 EC:4.1.1.38|KEGG_REACTION:R00346|RHEA:22356|MetaCyc:4.1.1.38-RXN phosphoenolpyruvate carboxylase (pyrophosphate)|PEPCTrP|phosphoenolpyruvic carboxytransphosphorylase activity|phosphoenolpyruvate carboxykinase (pyrophosphate) activity|phosphopyruvate carboxylase (pyrophosphate)|phosphoenolpyruvic carboxylase (pyrophosphate)|PEP carboxyphosphotransferase activity|phosphoenolpyruvate carboxytransphosphorylase activity|diphosphate:oxaloacetate carboxy-lyase (transphosphorylating)|phosphoenolpyruvic carboxykinase (pyrophosphate)|phosphopyruvate carboxykinase (pyrophosphate)|phosphoenolpyruvic carboxykinase|phosphopyruvate carboxykinase|diphosphate:oxaloacetate carboxy-lyase (transphosphorylating; phosphoenolpyruvate-forming)|phosphoenolpyruvate carboxyphosphotransferase activity Catalysis of the reaction: diphosphate + oxaloacetate = CO(2) + phosphate + phosphoenolpyruvate. GO:0030586 [methionine synthase] reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030586 Reactome:R-HSA-3149518|RHEA:23910|EC:1.16.1.8|MetaCyc:2.1.1.135-RXN methionine synthase reductase activity|methionine synthase-cobalamin methyltransferase (cob(II)alamin reducing)|[methionine synthase]-cobalamin methyltransferase (cob(II)alamin reducing) activity|methionine synthase-methylcob(I)alamin,S-adenosylhomocysteine:NADP+ oxidoreductase activity|methionine synthase cob(II)alamin reductase (methylating) activity|5-methyltetrahydrofolate-homocysteine methyltransferase reductase Catalysis of the reaction: [methionine synthase]-cob(II)alamin + NADPH + H+ + S-adenosyl methionine => [methionine synthase]-methylcob(I)alamin + S-adenosylhomocysteine + NADP+. GO:0030583 myxococcal fruiting body development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030583 fruiting body development in cellular response to starvation|fruiting body development in response to starvation The process whose specific outcome is the progression of the myxococcal fruiting body over time, from its formation to the mature structure. The process begins when myxococci respond to a lack of nutrients in the environment and ends when the myxococcal fruiting body is a mature structure. GO:0030584 sporocarp development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030584 fruiting body development The process whose specific outcome is the progression of a sporocarp over time, from its formation to the mature structure. The sporocarp is a spore bearing fruiting body organ. An example of this process is found in the Fungal species Coprinopsis cinerea. GO:0030581 symbiont intracellular protein transport in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030581 intracellular protein transport in other organism involved in symbiotic interaction|intracellular protein transport in other organism during symbiotic interaction|intracellular protein transport in host|host cell protein transport The directed movement of a symbiont's proteins within a cell of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0030582 reproductive fruiting body development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030582 fruiting body formation The process whose specific outcome is the progression of a reproductive fruiting body over time, from its formation to the mature structure. A reproductive fruiting body is a multicellular reproductive structure that contains spores. GO:0030580 quinone cofactor methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030580 Catalysis of the transfer of a methyl group from S-adenosylmethionine during the synthesis of quinone cofactors such as ubiquinone (coenzyme Q), menaquinone (vitamin K2), plastoquinone and phylloquinone (vitamin K1). GO:0030578 PML body organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030578 PML body organisation|PML body organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of PML bodies, a class of nuclear body; they react against SP100 auto-antibodies (PML = promyelocytic leukemia). GO:0030579 ubiquitin-dependent SMAD protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030579 ubiquitin-dependent SMAD protein catabolism|ubiquitin-dependent SMAD protein degradation|ubiquitin-dependent SMAD protein breakdown The chemical reactions and pathways resulting in the breakdown of SMAD signaling proteins by ubiquitination and targeting to the proteasome. GO:0030576 Cajal body organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030576 Cajal body organisation|Cajal body organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of Cajal bodies, nuclear bodies that appear ultrastructurally as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter and are enriched in ribonucleoproteins, and certain general RNA polymerase II transcription factors. GO:0030577 Lands organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030577 Lands organization and biogenesis|Lands organisation|LYSP100-associated nuclear domain organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of Lands, a class of nuclear body that react against SP140 auto-antibodies. GO:0030574 collagen catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030574 collagen catabolism|collagen degradation|collagen breakdown The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells. GO:0030575 nuclear body organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030575 nuclear body organization and biogenesis|nuclear body organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of any of the extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins. GO:0030572 phosphatidyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030572 Catalysis of the reaction involving the transfer of a phosphatidate (otherwise known as diacylglycerol 3-phosphosphate) group. GO:0030573 bile acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030573 MetaCyc:7ALPHADEHYDROX-PWY bile acid catabolism|cholate catabolic process|bile acid 7alpha-dehydroxylation pathway|bile acid degradation|bile acid breakdown The chemical reactions and pathways resulting in the breakdown of bile acids, any of a group of steroid carboxylic acids occurring in bile. GO:0030570 pectate lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030570 MetaCyc:4.2.2.2-RXN|EC:4.2.2.2 endo-alpha-1,4-polygalacturonic acid lyase activity|(1->4)-alpha-D-galacturonan lyase activity|pectic lyase activity|pectin trans-eliminase activity|pectate transeliminase activity|polygalacturonate lyase activity|PGA lyase activity|PPase-N activity|polygalacturonic transeliminase activity|polygalacturonic acid trans-eliminase activity|endogalacturonate transeliminase activity|endopectin methyltranseliminase activity|pectic acid transeliminase activity|alpha-1,4-D-endopolygalacturonic acid lyase activity|polygalacturonic acid lyase activity|pectic acid lyase activity Catalysis of the reaction: a pectate = a pectate + a pectate oligosaccharide with 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate end. This reaction is the eliminative cleavage of pectate to give oligosaccharides with 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their non-reducing ends. GO:0030571 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030571 GO:0030569 obsolete chymotrypsin inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030569 chymotrypsin inhibitor activity OBSOLETE. Stops, prevents or reduces the activity of the serine endopeptidase chymotrypsin. GO:0030567 obsolete thrombin activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030567 prothrombin activator activity|thrombin activator activity OBSOLETE. Increases the rate of proteolysis catalyzed by thrombin. GO:0030568 obsolete plasmin inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030568 plasmin inhibitor activity OBSOLETE. Stops, prevents or reduces the activity of the serine endopeptidase plasmin. GO:0030565 snRNA pseudouridylation guide activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030565 Activity that provides specificity to a pseudouridine synthetase by using base complementarity to guide site-specific pseudouridylations to a small nuclear RNA molecule. GO:0030566 snRNA modification guide activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030566 Specifies the site of a posttranscriptional modification in an snRNA molecule by base pairing with a short sequence around the target residue. CHEBI:149433 mannotetraose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_149433 CHEBI:43197 (R)-3-hydroxylauric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_43197 RO:0002598 capable of positively regulating biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002598 RO:0002598 Holds between c and p if and only if c is capable of some activity a, and a positively regulates p. GO:0030563 snRNA 2'-O-ribose methylation guide activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030563 Activity that provides specificity to a methylase by using base complementarity to guide site-specific 2'-O-ribose methylations to a small nuclear RNA molecule. GO:0030564 tRNA 2'-O-ribose methylation guide activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030564 Specifies the site of 2'-O-ribose methylation in a tRNA molecule by base pairing with a short sequence around the target residue. GO:0030561 RNA 2'-O-ribose methylation guide activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030561 Specifies the site of 2'-O-ribose methylation in an RNA molecule by base pairing with a short sequence around the target residue. GO:0030562 rRNA 2'-O-ribose methylation guide activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030562 Specifies the site of 2'-O-ribose methylation in an rRNA molecule by base pairing with a short sequence around the target residue. GO:0030560 tRNA pseudouridylation guide activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030560 Specifies the site of pseudouridylation in a tRNA molecule by base pairing with a short sequence around the target residue. GO:0030558 RNA pseudouridylation guide activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030558 Specifies the site of pseudouridylation in an RNA molecule by base pairing with a short sequence around the target residue. GO:0030559 rRNA pseudouridylation guide activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030559 Specifies the site of pseudouridylation in an rRNA molecule by base pairing with a short sequence around the target residue. GO:0030556 rRNA modification guide activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030556 Specifies the site of a posttranscriptional modification in an rRNA molecule by base pairing with a short sequence around the target residue. GO:0030557 tRNA modification guide activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030557 Specifies the site of a posttranscriptional modification in a tRNA molecule by base pairing with a short sequence around the target residue. GO:0030554 adenyl nucleotide binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0030554 Interacting selectively and non-covalently with adenyl nucleotides, any compound consisting of adenosine esterified with (ortho)phosphate. GO:0005598 short-chain collagen trimer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005598 Any collagen trimer that does not form fibrils and that is relatively short compared to the collagen trimers that do form fibrils. GO:0030555 RNA modification guide activity biolink:MolecularActivity go-plus goslim_yeast|goslim_generic http://purl.obolibrary.org/obo/GO_0030555 Specifies the site of a posttranscriptional modification in an RNA molecule by base pairing with a short sequence around the target residue. GO:0005599 collagen type X trimer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005599 A collagen homotrimer of alpha1(X) chains; type X collagen triple helices form hexagonal networks (sheets). CHEBI:149429 xylotriose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_149429 GO:0005596 collagen type XIV trimer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005596 A collagen homotrimer of alpha1(XIV) chains; type XIV collagen triple helices may link sheet-forming or fibrillar collagens to other structures. RO:0002595 causal relation between material entity and a process biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002595 RO:0002595 A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity. GO:0005597 collagen type XVI trimer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005597 A collagen trimer containing alpha(XVI) chains; type XVI trimers can associate with microfibrils. GO:0005594 collagen type IX trimer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005594 A collagen heterotrimer containing type IX alpha chains in alpha1(IX)alpha2(IX)alpha3(IX) trimers; type IX collagen triple helices associate to form a structure that links glycosaminoglycans to type II collagen fibrils. RO:0002596 capable of regulating biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002596 RO:0002596 Holds between c and p if and only if c is capable of some activity a, and a regulates p. RO:0002597 capable of negatively regulating biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002597 RO:0002597 Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p. GO:0005595 collagen type XII trimer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005595 A collagen homotrimer of alpha1(XII) chains; type XII collagen triple helices may link sheet-forming or fibrillar collagens to other structures. GO:0005592 collagen type XI trimer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005592 A collagen heterotrimer containing type XI alpha chains in alpha1(XI)alpha2(XI)alpha3(XI) trimers; type XI collagen triple helices associate to form fibrils. RO:0002590 results_in_disassembly_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002590 RO:0002590 GO:0005593 FACIT collagen trimer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005593 Wikipedia:FACIT_collagen A collagen trimer that associates with collagen fibrils and consists of collagen monomers that contain two or more relatively short triple-helical domains connected by non-triple-helical sequences. RO:0002591 results in remodeling of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002591 RO:0002591 GO:0005590 collagen type VII trimer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005590 A collagen homotrimer of alpha1(VII) chains; type VII collagen triple helices form antiparallel dimer, which in turn associate laterally to form anchoring fibrils that connect type IV collagen in the basal lamina to plaques in the underlying connective tissue. It binds laminin. CHEBI:43186 5-hydroxy-D-tryptophan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_43186 RO:0002592 results_in_organization_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002592 RO:0002592 p results in organization of c iff p results in the assembly, arrangement of constituent parts, or disassembly of c GO:0005591 collagen type VIII trimer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005591 A collagen heterotrimer containing type VIII alpha chains; [alpha1(VIII)2]alpha2(VIII) and alpha1(VIII)[alpha2(VIII)]2 trimers have been observed; type VIII collagen triple helices associate to form regular hexagonal nets. RO:0002588 results_in_assembly_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002588 RO:0002588 GO:0030552 cAMP binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030552 3',5'-cAMP binding|adenosine 3',5'-cyclophosphate binding|cyclic AMP binding|3',5' cAMP binding Interacting selectively and non-covalently with cAMP, the nucleotide cyclic AMP (adenosine 3',5'-cyclophosphate). GO:0030553 cGMP binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030553 3',5'-cGMP binding|cyclic GMP binding|3',5' cGMP binding Interacting selectively and non-covalently with cGMP, the nucleotide cyclic GMP (guanosine 3',5'-cyclophosphate). GO:0030550 acetylcholine receptor inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030550 Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is decreased. GO:0030551 cyclic nucleotide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030551 Interacting selectively and non-covalently with a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue. GO:0030549 acetylcholine receptor activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030549 Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is increased. GO:0030547 receptor inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030547 The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is decreased. GO:0030548 acetylcholine receptor regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030548 Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is changed. GO:0030545 receptor regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030545 The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is changed. GO:0030546 signaling receptor activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030546 signalling receptor activator activity|receptor activator activity The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is increased. GO:0030543 2-micrometer plasmid partitioning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030543 The process in which copies of the 2-micrometer plasmid, found in fungi such as Saccharomyces, are distributed to daughter cells upon cell division. GO:0030544 Hsp70 protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030544 Interacting selectively and non-covalently with Hsp70 proteins, any of a group of heat shock proteins around 70kDa in size. RO:0002584 has part structure that is capable of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002584 RO:0002584 s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p RO:0002586 results in breakdown of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002586 RO:0002586 p results in breakdown of c if and only if the execution of p leads to c no longer being present at the end of p CHEBI:43176 hydroxy group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_43176 RO:0002576 skeleton of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002576 RO:0002576 RO:0002578 directly regulates biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002578 RO:0002578 Process(P1) directly regulates process(P2) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2. GO:0030541 plasmid partitioning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030541 Any process in which plasmids are segregated or distributed into daughter cells upon cell division. GO:0030542 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030542 GO:0030540 female genitalia development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030540 female genital development The process whose specific outcome is the progression of the female genitalia over time, from formation to the mature structure. CHEBI:67132 ditrans,polycis-polyprenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67132 CHEBI:82769 caldopentamine(4+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82769 CHEBI:82767 4-(5-O-phosphonato-beta-D-ribofuranosyl)phenol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82767 RO:0002572 luminal space of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002572 RO:0002572 CHEBI:67138 UDP-N-acetyl-alpha-D-galactosamine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67138 CHEBI:82768 caldopentamine(5+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82768 CHEBI:67139 (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67139 CHEBI:82765 1,2-dioctanoyl-sn-glycerol 3-diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82765 CHEBI:82766 2-O-(alpha-D-glucopyranosyl)glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82766 CHEBI:82763 1-heptadecanoyl-2-arachidonoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82763 CHEBI:67133 UDP-2-acetamido-4-azaniumyl-2,4,6-trideoxy-alpha-D-glucose(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67133 CHEBI:67134 UDP-N,N'-diacetylbacillosamine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67134 CHEBI:82764 O-[S-2-methylbutanoylpantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82764 CHEBI:67135 2-nitroimidazole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67135 RO:0002571 lumen of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002571 RO:0002571 CHEBI:67136 cannabidiolate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67136 CHEBI:82762 1-oleoyl-2-arachidonoyl-sn-glycero-3-phospho-1D-myo-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82762 RO:0002569 has branching part biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002569 RO:0002569 RO:0002565 results in movement of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002565 RO:0002565 Holds between p and c when p is locomotion process and the outcome of this process is the change of location of c RO:0002566 causally influences biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002566 RO:0002566 The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size). RO:0002568 has_muscle_antagonist biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002568 RO:0002568 m1 has_muscle_antagonist m2 iff m1 acts in opposition to m2, and m2 is responsible for returning the structure to its initial position. CHEBI:546274 (4-hydroxy-3-nitrophenyl)acetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_546274 CHEBI:67140 phosphate monoester dianion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67140 CHEBI:33808 galacturonic acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33808 CHEBI:67142 nucleobase analogue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67142 CHEBI:67143 pppA2'p5'A2'p5'A biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67143 CHEBI:67148 2-hydroxybenzoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67148 CHEBI:33801 D-glucarate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33801 CHEBI:33804 gluconates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33804 CHEBI:82774 (R)-3,5-bisphosphonatomevalonate(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82774 CHEBI:67145 fumigaclavine A(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67145 CHEBI:82775 5'-deoxyinosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82775 CHEBI:33805 2-amino-2-deoxy-D-gluconate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33805 CHEBI:67146 fumigaclavine B(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67146 CHEBI:82772 N(4)-aminopropylspermine(5+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82772 CHEBI:67147 fumigaclavine C(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67147 CHEBI:82773 (R)-3-phosphonatomevalonate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82773 CHEBI:82770 N(4)-aminopropylspermidine(4+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82770 CHEBI:82771 N(4)-bis(aminopropyl)spermidine(5+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82771 RO:0002559 causally influenced by biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002559 RO:0002559 CHEBI:67152 (2Z)-2-hydroxypenta-2,4-dienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67152 CHEBI:67153 (+)-larreatricin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67153 CHEBI:67154 (+)-3'-hydroxylarreatricin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67154 CHEBI:67150 beta-D-Glc-(1->3')-1,2-diacylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67150 CHEBI:67159 fumigaclavine A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67159 RO:0002551 has skeleton biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002551 RO:0002551 has sekeletal support|has supporting framework A relation between a subdivision of an organism and the single subdivision of skeleton that provides structural support for that subdivision. CHEBI:67156 fumigaclavine B biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67156 CHEBI:67158 (R)-3-ammonio-3-phenylpropanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67158 PR:000028205 type III interferon biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000028205 IFN type III|interferon type III|interferon lambda A class 2 cytokine, IL-10 type that binds to a specific cell surface receptor complex known as the IFN type III receptor, a heterodimer consisting of IFNLR1 and IL-10R2. CHEBI:82798 cembrene C biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82798 CHEBI:82799 (R)-nephthenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82799 CHEBI:67168 UDP-N-acetyl-alpha-D-galactosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67168 CHEBI:82795 gamma-methyl L-glutamate residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82795 PR:000018880 acrosin proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000018880 ACR/ClvPrd An acrosin that has been processed by proteolytic cleavage. CHEBI:67176 1-deoxy-3-dehydrosphinganine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67176 CHEBI:67172 (R)-3-amino-3-phenylpropanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67172 CHEBI:67177 1-deoxymethyl-3-dehydrosphinganine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67177 CHEBI:67178 UDP-N,N'-diacetylbacillosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67178 PR:000028269 thyroid stimulating hormone biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000028269 TSH|thyrotropin A protein complex that is a heterodimer of an alpha subunit (CGA) common to several glycoprotein hormones and a beta subunit (TSHB) unique to thyroid stimulating hormone. CHEBI:67186 1-deoxymethyl-3-dehydrosphinganine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67186 CHEBI:67187 1-deoxymethylsphinganine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67187 CHEBI:67182 sporulenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67182 CHEBI:67188 9-cis-beta-carotene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67188 CHEBI:67189 EC 3.4.24.3 (microbial collagenase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67189 CHEBI:67190 carlactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67190 CHEBI:67195 gap junctional intercellular communication inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67195 CHEBI:67196 phytocannabinoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67196 CHEBI:67197 endocannabinoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67197 CHEBI:67198 retinoic acid receptor agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67198 CHEBI:67191 (2E,4E,6E)-7-hydroxy-4-methylhepta-2,4,6-trienal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67191 CHEBI:67192 9-cis-10'-apo-beta-carotenal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67192 CHEBI:67193 4-methylheptane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67193 CHEBI:67194 cannabinoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67194 CHEBI:67199 AP-1 antagonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67199 RO:0002505 has intermediate biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002505 RO:0002505 p has intermediate c if and only if p has parts p1, p2 and p1 has output c, and p2 has input c RO:0002506 causal relation between entities biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002506 RO:0002506 RO:0002500 causal agent in process biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002500 RO:0002500 A relationship between a material entity and a process where the material entity has some causal role that influences the process RO:0002501 causal relation between processes biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002501 RO:0002501 p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one of direct activation or direct inhibition. p may be upstream, downstream, part of or a container of q. RO:0002502 depends on biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002502 RO:0002502 CHEBI:149499 (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl derivative biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_149499 CHEBI:149498 (7Z,10Z,13Z,16Z)-docosatetraenoyl derivative biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_149498 UBERON:0018543 lumen of intestine biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018543 gut lumen|intestine lumen|intestinal lumen The anatomical space within the intestine. CHEBI:57729 3alpha-hydroxyglycyrrhetinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57729 CHEBI:57727 N-formylmethanofuran(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57727 CHEBI:57728 morphiniumone(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57728 CHEBI:57726 D-proline zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57726 UBERON:0018544 trigeminal nerve muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018544 muscles innervated by the trigeminal nerve|muscle innervated by the trigeminal nerve Muscle innervated by the trigeminal nerve (Cranial Nerve V). CHEBI:33752 hexonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33752 CHEBI:18119 ethyl 3-oxohexanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18119 CHEBI:33753 pentonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33753 CHEBI:33754 trionic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33754 CHEBI:18117 3-ADP-2-phosphoglyceric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18117 CHEBI:18118 L-xylono-1,4-lactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18118 CHEBI:33755 tetronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33755 CHEBI:57723 sucrose 6(F)-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57723 CHEBI:18115 4-hydroxymandelonitrile biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18115 CHEBI:57724 dCTP(3-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_57724 CHEBI:18116 pseudouridine 5'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18116 CHEBI:57721 3-amino-L-alanine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57721 CHEBI:18113 D-galactosyl-(1->3)-N-acetyl-beta-D-galactosamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18113 CHEBI:57722 N(2),N(5)-dibenzoyl-L-ornithinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57722 CHEBI:18111 ribosomal RNA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18111 CHEBI:57720 alpha-D-ribose 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57720 CHEBI:18112 2-aminophenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18112 RO:0002608 process has causal agent biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0002608 RO:0002608 Inverse of 'causal agent in process' CHEBI:18110 3-phosphonatooxypyruvate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18110 GO:0005505 obsolete heavy metal binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005505 heavy metal binding OBSOLETE. Interacting selectively with a heavy metal, a metal that can form a coordination bond with a protein, as opposed to an alkali or alkaline-earth metal that can only form an ionic bond; this definition includes the following biologically relevant heavy metals: Cd, Co, Cu, Fe, Hg, Mn, Mo, Ni, V, W, Zn. GO:0005506 iron ion binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005506 iron binding Interacting selectively and non-covalently with iron (Fe) ions. GO:0005503 all-trans retinal binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005503 vitamin A binding|all-trans retinaldehyde binding|trans retinal binding|xanthopsin|visual yellow binding Interacting selectively and non-covalently with all-trans retinal, a compound that plays an important role in the visual process in most vertebrates. All-trans retinal (trans r., visual yellow) results from the bleaching of rhodopsin by light, in which the 11-cis form is converted to the all-trans form. Retinal is one of the forms of vitamin A. CHEBI:57718 barbiturate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_57718 GO:0005504 fatty acid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005504 Interacting selectively and non-covalently with fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis. CHEBI:57719 D-tryptophan zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57719 GO:0005501 retinoid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005501 Reactome:R-HSA-2454113|Reactome:R-HSA-2465938|Reactome:R-HSA-2465934|Reactome:R-HSA-2464809 Interacting selectively and non-covalently with retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity. CHEBI:57716 O-acetyl-L-homoserine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57716 GO:0005502 11-cis retinal binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005502 11-cis-retinal binding|vitamin A binding|11-cis retinaldehyde binding Interacting selectively and non-covalently with 11-cis retinal, an isomer of retinal that plays an important role in the visual process in most vertebrates. 11-cis retinal combines with opsin in the rods (scotopsin) to form rhodopsin or visual purple. Retinal is one of the three compounds that makes up vitamin A. CHEBI:57714 2-ureidoglycine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57714 GO:0005500 juvenile hormone binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005500 Interacting selectively and non-covalently with juvenile hormone, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis. CHEBI:57715 UDP-N-acetyl-D-mannosamine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57715 CHEBI:33767 cobalt group molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33767 CHEBI:33769 fuconates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33769 CHEBI:33760 hexonate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33760 CHEBI:33761 pentonate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33761 CHEBI:33762 tetronate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33762 CHEBI:33763 trionate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33763 CHEBI:33764 arabinonates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33764 CHEBI:18106 deacetylipecoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18106 CHEBI:18107 xanthosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18107 CHEBI:57712 2-hydroxy-3-oxoadipate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57712 CHEBI:18104 2-dehydro-3-deoxy-D-fuconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18104 CHEBI:57713 3-(2-carboxylatoethenyl)-cis,cis-muconate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57713 CHEBI:57710 5,12-dihydroxanthommatin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57710 CHEBI:18102 O-octanoyl-L-carnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18102 CHEBI:18103 L-tyrosine methyl ester 4-sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18103 CHEBI:57711 all-trans-octaprenyl diphosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57711 GO:0005509 calcium ion binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005509 calcium ion storage activity Interacting selectively and non-covalently with calcium ions (Ca2+). CHEBI:18100 multi-methyl-branched fatty acyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18100 CHEBI:18101 4-hydroxyphenylacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18101 GO:0005507 copper ion binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005507 copper/cadmium binding|copper binding Interacting selectively and non-covalently with copper (Cu) ions. GO:0005508 obsolete copper/cadmium binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005508 copper/cadmium binding OBSOLETE. (Was not defined before being made obsolete). CHEBI:18140 hydrogen halide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18140 CHEBI:57709 2-amino-3-oxo-4-(phosphonatooxy)butanoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_57709 CHEBI:57707 2,3-bis-O-(geranylgeranyl)glycerol 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57707 CHEBI:82707 ergothioneine thione form biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82707 CHEBI:57708 benzoylagmatinium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57708 CHEBI:57705 UDP-N-acetyl-alpha-D-glucosamine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57705 CHEBI:82705 hercynylselenocysteine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82705 CHEBI:82706 hercynylcysteine sulfoxide zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82706 CHEBI:57706 4-oxobutanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57706 CHEBI:57703 2-nitrophenolate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57703 CHEBI:82703 N(alpha)-(L-gamma-glutamyl)-hercynyl-L-cysteine sulfoxide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82703 CHEBI:57704 cationic chitosan biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57704 CHEBI:33737 di-mu-sulfido-diiron(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33737 CHEBI:33738 di-mu-sulfido-diiron(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33738 CHEBI:33731 cluster biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33731 CHEBI:18139 trimethylamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18139 CHEBI:33733 heteronuclear cluster biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33733 CHEBI:57701 5-O-(1-carboxylatovinyl)-3-phosphonatoshikimate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57701 CHEBI:18137 heparan sulfate alpha-D-glucosaminide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18137 CHEBI:57702 N-acetyl-L-phenylalaninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57702 CHEBI:18138 biuret biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18138 CHEBI:18135 catechol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18135 CHEBI:18136 3-(2,3-dihydroxyphenyl)propanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18136 CHEBI:57700 2-methyl-3-oxopropanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57700 CHEBI:18133 hexose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18133 CHEBI:18134 3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18134 CHEBI:18131 licodione biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18131 CHEBI:18132 phosphocholine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18132 CHEBI:18130 (-)-5-oxo-1,2-campholide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18130 CHEBI:33745 copper group molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33745 CHEBI:33746 vanadium group molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33746 CHEBI:82710 S-alkyl-L-cysteine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82710 CHEBI:33747 nickel group molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33747 CHEBI:33748 nickel molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33748 CHEBI:82711 aryl thiol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82711 CHEBI:33749 platinum molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33749 CHEBI:33741 chromium group molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33741 CHEBI:33742 tungsten molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33742 UBERON:0018508 foramen of nasal bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0018508 foramen of nasal bone|nasal foramina|foramina nasalia|nasal foramen A vascular foramen opening on the outer surface of a nasal bone. CHEBI:33743 manganese group molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33743 CHEBI:18128 luteolin 7-O-beta-D-glucosiduronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18128 CHEBI:18129 (S)-2-hydroxyoctadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18129 CHEBI:33744 iron group molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33744 CHEBI:18126 S-acylglutathione biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18126 CHEBI:18127 cadaverine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18127 CHEBI:18124 phosphonoacetaldehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18124 CHEBI:18125 trans-2-coumaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18125 CHEBI:18123 N-methylnicotinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18123 CHEBI:18120 5-aminopentanamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18120 CHEBI:82728 S-(5-histidyl)cysteine sulfoxide dizwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82728 CHEBI:33712 N-terminal amino-acid residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33712 CHEBI:33713 C-terminal alpha-amino-acid residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33713 CHEBI:33715 N-terminal alpha-amino-acid residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33715 CHEBI:33716 N-terminal proteinogenic amino-acid residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33716 CHEBI:33717 C-terminal proteinogenic amino-acid residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33717 CHEBI:33719 alpha-amino-acid cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33719 CHEBI:33710 alpha-amino-acid residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33710 CHEBI:33711 C-terminal amino-acid residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33711 CHEBI:82736 N-acylphytosphingosine-1-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82736 CHEBI:82737 N-hexadecanoylphytosphingosine-1-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82737 CHEBI:82734 N-acylsphinganine-1-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82734 CHEBI:33723 tetra-mu3-sulfido-tetrairon(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33723 CHEBI:67104 4-nitro-6-oxohepta-2,4-dienedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67104 CHEBI:82735 O-[S-(6-methoxycarbonylhexanoyl)pantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82735 CHEBI:82732 N-hexadecanoylsphinganine-1-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82732 CHEBI:67106 1-deoxysphinganine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67106 CHEBI:33726 proteinogenic amino-acid residue anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33726 CHEBI:33727 proteinogenic amino-acid residue cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33727 CHEBI:82730 (7Z)-hexadecenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82730 CHEBI:33728 proteinogenic amino-acid residue radical biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33728 CHEBI:33729 tetritol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33729 CHEBI:67103 (2E,4Z)-4-hydroxy-6-oxohexa-2,4-dienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67103 CHEBI:67108 1-deoxymethylsphinganine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67108 CHEBI:67109 1-deoxysphinganine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67109 CHEBI:33720 carbohydrate acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33720 CHEBI:33721 carbohydrate acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33721 CHEBI:33722 tetra-mu3-sulfido-tetrairon(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33722 CHEBI:82747 (9Z,12Z)-heptadecadienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82747 CHEBI:82748 cytidine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82748 CHEBI:82745 (9Z,12Z)-tetradecadienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82745 CHEBI:67115 ecgonone methyl ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67115 CHEBI:82746 (9Z,12Z)-pentadecadienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82746 CHEBI:82743 5-methylaminomethyl-2-selenouridine 5'-monophosphate zwitterion residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82743 CHEBI:67117 trans,octacis-decaprenylphospho-beta-D-ribofuranose 5-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67117 CHEBI:82744 aliphatic aldoxime biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82744 CHEBI:67118 UDP-alpha-D-galactofuranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67118 CHEBI:82741 (5Z,11Z,14Z,17Z)-icosatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82741 CHEBI:82742 (8Z,11Z)-icosadienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82742 CHEBI:67114 ryanodine receptor agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67114 CHEBI:82740 (5Z,11Z,14Z)-icosatrienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82740 CHEBI:67119 UDP-alpha-D-galactose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67119 CHEBI:33709 amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33709 CHEBI:82759 (S)-3-acetyloctanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82759 CHEBI:33702 polyatomic cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33702 CHEBI:82757 2-hydroxy-5-methyl-1-naphthoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82757 CHEBI:33703 amino-acid cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33703 CHEBI:33704 alpha-amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33704 CHEBI:67122 alpha-D-abequosyl-(1->3)-alpha-D-mannosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-beta-D-galactosyl-1-diphosphodecaprenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67122 CHEBI:82753 1-oleoyl-sn-glycero-3-phospho-D-myo-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_82753 CHEBI:33706 beta-amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33706 CHEBI:33707 gamma-amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33707 CHEBI:82750 cholesteryl stearate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82750 CHEBI:67124 alpha-D-mannosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-beta-D-galactosyl-1-diphosphodecaprenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_67124 CHEBI:82751 cholesteryl arachidonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82751 CHEBI:33708 amino-acid residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33708 CHEBI:33700 proteinogenic amino-acid residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33700 NCBITaxon:78536 Euphyllophyta organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_78536 euphyllophytes GO:0030538 embryonic genitalia morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030538 embryonic genital morphogenesis The process, occurring in the embryo, by which the anatomical structures of the genitalia are generated and organized. GO:0030539 male genitalia development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030539 male genital development The process whose specific outcome is the progression of the male genitalia over time, from its formation to the mature structure. GO:0030536 larval feeding behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030536 larval feeding behaviour Feeding behavior in a larval (immature) organism. GO:0030537 larval behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030537 larval behaviour Behavior in a larval form of an organism, an immature organism that must undergo metamorphosis to assume adult characteristics. GO:0030534 adult behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030534 adult behavioural response to stimulus|adult behavioral response to stimulus|adult behaviour Behavior in a fully developed and mature organism. GO:0005578 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005578 GO:0005579 membrane attack complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005579 Wikipedia:Complement_membrane_attack_complex TCC|membrane attack complex protein beta2 chain|MAC|membrane attack complex protein alphaM chain|terminal complement complex A protein complex produced by sequentially activated components of the complement cascade inserted into a target cell membrane and forming a pore leading to cell lysis via ion and water flow. GO:0030535 obsolete adult feeding behavior (sensu Insecta) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030535 adult feeding behavior (sensu Insecta) OBSOLETE. Feeding behavior in a fully developed and mature organism, as described in insects. GO:0005576 extracellular region biolink:CellularComponent go-plus goslim_mouse|goslim_yeast|goslim_candida|goslim_agr|goslim_plant|goslim_pir|goslim_aspergillus|goslim_metagenomics|goslim_generic|goslim_flybase_ribbon|goslim_chembl http://purl.obolibrary.org/obo/GO_0005576 Wikipedia:Extracellular extracellular The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. GO:0030532 small nuclear ribonucleoprotein complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0030532 Wikipedia:SnRNP snRNP|small nuclear ribonucleoprotein A ribonucleoprotein complex that contains at least one RNA of the small nuclear RNA (snRNA) class and as well as its associated proteins. These are typically named after the snRNA(s) they contain, e.g. U1 snRNP, U4/U6 snRNP, or 7SK snRNP. Many, of these complexes become part of the spliceosome involved in splicing of nuclear mRNAs. Others are involved in regulation of transcription elongation or 3'-end processing of replication-dependent histone pre-mRNAs. GO:0005577 fibrinogen complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005577 fibrinogen gamma chain|fibrinogen alpha chain|fibrinogen beta chain|fibrinogen A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds. GO:0030533 triplet codon-amino acid adaptor activity biolink:MolecularActivity go-plus goslim_chembl|goslim_yeast|goslim_candida|goslim_aspergillus|goslim_generic http://purl.obolibrary.org/obo/GO_0030533 tRNA|transfer RNA The codon binding activity of a tRNA that positions an activated amino acid, mediating its insertion at the correct point in the sequence of a nascent polypeptide chain during protein synthesis. GO:0005574 obsolete DNA biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005574 DNA OBSOLETE. (Was not defined before being made obsolete). GO:0005575 cellular_component biolink:CellularComponent go-plus goslim_yeast|goslim_candida|goslim_plant|goslim_pir|goslim_aspergillus|goslim_metagenomics|goslim_generic|goslim_chembl http://purl.obolibrary.org/obo/GO_0005575 NIF_Subcellular:sao1337158144 cellular component|subcellular entity|cell or subcellular entity A location, relative to cellular compartments and structures, occupied by a macromolecular machine when it carries out a molecular function. There are two ways in which the gene ontology describes locations of gene products: (1) relative to cellular structures (e.g., cytoplasmic side of plasma membrane) or compartments (e.g., mitochondrion), and (2) the stable macromolecular complexes of which they are parts (e.g., the ribosome). GO:0005572 obsolete RNA polymerase II transcribed untranslated RNA biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005572 RNA polymerase II transcribed untranslated RNA OBSOLETE. (Was not defined before being made obsolete). GO:0005573 obsolete telomerase RNA biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005573 telomerase RNA OBSOLETE. (Was not defined before being made obsolete). GO:0005570 obsolete small nuclear RNA biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005570 small nuclear RNA OBSOLETE. (Was not defined before being made obsolete). GO:0005571 obsolete untranslated RNA biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005571 untranslated RNA OBSOLETE. (Was not defined before being made obsolete). GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030530 Wikipedia:Heterogeneous_ribonucleoprotein_particle heterogeneous nuclear ribonucleoprotein|hnRNP|heterogeneous nuclear ribonucleoprotein complex OBSOLETE. Particulate complex of heterogeneous nuclear RNA (hnRNA; a heterogeneous mixture of RNA molecules of high Mr with a rapid turnover rate that occurs in cell nuclei during protein synthesis; it is the form of RNA synthesized in eukaryotes by RNA polymerase II, that which is translated into protein) with protein, which is cell-specific and heterogeneous. The protein component may play a role in the processing of the hnRNA to mRNA. GO:0030531 obsolete small cytoplasmic ribonucleoprotein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030531 small cytoplasmic ribonucleoprotein|small cytoplasmic ribonucleoprotein complex|scRNP OBSOLETE. A complex composed of RNA of the small cytoplasmic RNA (scRNA) class and protein, found in the cytoplasm. CHEBI:18199 UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18199 CHEBI:18197 ditrans,polycis-undecaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18197 CHEBI:18198 4-amino-4-deoxychorismic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18198 CHEBI:18195 alpha,alpha'-trehalose 6,6'-bismycolate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18195 GO:0030527 structural constituent of chromatin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030527 The action of a molecule that contributes to the structural integrity of chromatin. GO:0030528 obsolete transcription regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030528 transcriptional regulator activity|transcription regulator activity OBSOLETE. Plays a role in regulating transcription; may bind a promoter or enhancer DNA sequence or interact with a DNA-binding transcription factor. CHEBI:18193 10-deacetylbaccatin III biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18193 GO:0030525 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030525 GO:0030526 granulocyte macrophage colony-stimulating factor receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0030526 GM-CSF receptor complex|granulocyte macrophage colony stimulating factor receptor complex The heterodimeric receptor for granulocyte macrophage colony-stimulating factor. GO:0030523 dihydrolipoamide S-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030523 EC:2.3.1.12 Catalysis of the reaction: acyl-CoA + dihydrolipoamide = CoA + S-acyldihydrolipoamide. GO:0005589 collagen type VI trimer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005589 A collagen heterotrimer containing type VI alpha chains in alpha1(VI)alpha2(VI)alpha3(VI) trimers; type VI collagen triple helices associate to form beaded fibrils. GO:0030524 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030524 GO:0005587 collagen type IV trimer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005587 Wikipedia:Collagen_type_IV A collagen heterotrimer containing type IV alpha chains; [alpha1(IV)]2alpha2(IV) trimers are commonly observed, although more type IV alpha chains exist and may be present in type IV trimers; type IV collagen triple helices associate to form 3 dimensional nets within basement membranes. GO:0030521 androgen receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030521 androgen receptor signalling pathway Any series of molecular signals generated as a consequence of an androgen binding to its receptor. GO:0030522 intracellular receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030522 intracellular receptor-mediated signaling pathway|intracellular receptor-mediated signalling pathway|intracellular receptor mediated signaling pathway Any series of molecular signals initiated by a ligand binding to an receptor located within a cell. GO:0005588 collagen type V trimer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005588 A collagen heterotrimer containing type V alpha chains; [alpha1(V)]2alpha2(V) and alpha1(V)alpha2(V)alpha3(V) trimers have been observed; type V collagen triple helices associate to form fibrils. GO:0005585 collagen type II trimer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005585 Wikipedia:Collagen_type_II A collagen homotrimer of alpha1(II) chains; type II collagen triple helices associate to form fibrils. GO:0005586 collagen type III trimer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005586 A collagen homotrimer of alpha1(III) chains; type III collagen triple helices associate to form fibrils. GO:0005583 fibrillar collagen trimer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005583 Any triple helical collagen trimer that forms fibrils. GO:0005584 collagen type I trimer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005584 Wikipedia:Collagen_type_I A collagen trimer containing alpha(I) chains. The most common form of type I collagen is a heterotrimer containing two alpha1(I) chains and one alpha2(I) chain; homotrimers containing three alpha1(I) chains are also found. Type I collagen triple helices associate to form banded fibrils. GO:0005581 collagen trimer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005581 Wikipedia:Collagen A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures. GO:0005582 collagen type XV trimer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005582 A collagen homotrimer of alpha1(XV) chains; a chondroitin sulfate proteoglycan often found in specialized basement membranes where it bridges between fibrils. GO:0030529 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030529 GOREL:0001006 acts_on_population_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GOREL_0001006 GOREL:0001006 alters levels of GO:0005580 obsolete membrane attack complex protein alphaM chain biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005580 membrane attack complex protein alphaM chain OBSOLETE. (Was not defined before being made obsolete). CHEBI:57792 1-deoxy-D-xylulose 5-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57792 CHEBI:57790 benzyl cetraxate(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57790 CHEBI:57791 meso-2,6-diaminopimelic acid dizwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57791 GO:0030520 intracellular estrogen receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030520 estrogen receptor signalling pathway|estrogen receptor signaling pathway Any series of molecular signals generated as a consequence of an intracellular estrogen receptor binding to one of its physiological ligands. The pathway begins with receptor-ligand binding, and ends with regulation of a downstream cellular process (e.g. transcription). CHEBI:57798 1D-myo-inositol 1,2,4,5,6-pentakisphosphate(10-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57798 CHEBI:57799 4',5-dihydroxy-3'-methoxyflavon-7-olate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57799 CHEBI:18188 (S)-3-aminoisobutyrate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18188 CHEBI:57797 dihydrostreptomycin 6-phosphate(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57797 CHEBI:18186 tyrosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18186 CHEBI:57794 dGTP(3-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_57794 CHEBI:57795 1-phosphatidyl-1D-myo-inositol 5-phosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57795 CHEBI:18187 (E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18187 GO:0030516 regulation of axon extension biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030516 Any process that modulates the rate, direction or extent of axon extension. GO:0030517 negative regulation of axon extension biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030517 down-regulation of axon extension|downregulation of axon extension|down regulation of axon extension|inhibition of axon extension Any process that stops, prevents, or reduces the frequency, rate or extent of axon outgrowth. GO:0030514 negative regulation of BMP signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030514 negative regulation of BMP signalling pathway|negative regulation of bone morphogenetic protein signaling pathway|down regulation of BMP signaling pathway|downregulation of BMP signaling pathway|negative regulation of BMP receptor signaling pathway|negative regulation of decapentaplegic receptor signaling pathway|negative regulation of bone morphogenetic protein signalling pathway|negative regulation of decapentaplegic receptor signalling pathway|down-regulation of BMP signaling pathway|negative regulation of decapentaplegic signaling pathway|inhibition of BMP signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway. GO:0005558 obsolete minor histocompatibility antigen biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005558 minor histocompatibility antigen OBSOLETE. (Was not defined before being made obsolete). CHEBI:149502 (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl derivative biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_149502 GO:0005559 obsolete ribozyme biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005559 ribozyme OBSOLETE. (Was not defined before being made obsolete). GO:0030515 snoRNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030515 Interacting selectively and non-covalently with small nucleolar RNA. GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030512 negative regulation of transforming growth factor beta receptor signalling pathway|down regulation of transforming growth factor beta receptor signaling pathway|inhibition of transforming growth factor beta receptor signaling pathway|negative regulation of TGFbeta receptor signaling pathway|negative regulation of TGF-beta receptor signaling pathway|down-regulation of transforming growth factor beta receptor signaling pathway|downregulation of transforming growth factor beta receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway. GO:0030513 positive regulation of BMP signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030513 positive regulation of BMP signalling pathway|upregulation of BMP signaling pathway|positive regulation of bone morphogenetic protein signaling pathway|positive regulation of bone morphogenetic protein signalling pathway|positive regulation of decapentaplegic receptor signalling pathway|up regulation of BMP signaling pathway|positive regulation of BMP receptor signaling pathway|activation of BMP signaling pathway|positive regulation of decapentaplegic receptor signaling pathway|positive regulation of decapentaplegic signaling pathway|stimulation of BMP signaling pathway|up-regulation of BMP signaling pathway Any process that activates or increases the frequency, rate or extent of BMP signaling pathway activity. GO:0005557 obsolete lymphocyte antigen biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005557 lymphocyte antigen OBSOLETE. (Was not defined before being made obsolete). GO:0030510 regulation of BMP signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030510 regulation of bone morphogenetic protein signalling pathway|regulation of decapentaplegic receptor signalling pathway|regulation of decapentaplegic signaling pathway|regulation of BMP signalling pathway|regulation of bone morphogenetic protein signaling pathway|regulation of BMP receptor signaling pathway|regulation of decapentaplegic receptor signaling pathway Any process that modulates the frequency, rate or extent of the activity of any BMP receptor signaling pathway. GO:0005554 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005554 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030511 positive regulation of TGF-beta receptor signaling pathway|upregulation of transforming growth factor beta receptor signaling pathway|positive regulation of TGFbeta receptor signaling pathway|stimulation of transforming growth factor beta receptor signaling pathway|up-regulation of transforming growth factor beta receptor signaling pathway|activation of transforming growth factor beta receptor signaling pathway|up regulation of transforming growth factor beta receptor signaling pathway|positive regulation of transforming growth factor beta receptor signalling pathway Any process that activates or increases the frequency, rate or extent of TGF-beta receptor signaling pathway activity. GO:0005555 obsolete blood group antigen biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005555 blood group antigen OBSOLETE. (Was not defined before being made obsolete). GO:0005552 obsolete polyubiquitin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005552 polyubiquitin OBSOLETE. (Was not defined before being made obsolete). GO:0005553 obsolete ubiquitin-ribosomal protein fusion protein biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005553 ubiquitin-ribosomal protein fusion protein OBSOLETE. A protein encoded by some ubiquitin genes which consists of a single copy of ubiquitin fused to a ribosomal protein. GO:0005550 pheromone binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005550 Interacting selectively and non-covalently with a pheromone, a substance, or characteristic mixture of substances, that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process. GO:0005551 obsolete ubiquitin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005551 OBSOLETE. (Was not defined before being made obsolete). CHEBI:149500 (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl derivative biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_149500 GO:0030518 intracellular steroid hormone receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030518 steroid hormone receptor signalling pathway|steroid hormone receptor signaling pathway A series of molecular signals generated as a consequence of a intracellular steroid hormone receptor binding to one of its physiological ligands. GO:0030519 snoRNP binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030519 Interacting selectively and non-covalently with any part of a small nucleolar ribonucleoprotein particle. CHEBI:57781 N-methylethanolaminium phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57781 CHEBI:57782 cortisol 21-sulfate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57782 CHEBI:149509 candesartan(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_149509 CHEBI:57787 streptomycin 6-phosphate(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57787 CHEBI:57788 isonocardicin A(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_57788 CHEBI:57783 NADPH(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57783 CHEBI:57784 2-[3-carboxylato-3-(methylammonio)propyl]-L-histidine dizwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57784 GO:0030505 inorganic diphosphate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030505 inorganic pyrophosphate transport The directed movement of inorganic diphosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0030506 ankyrin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030506 Interacting selectively and non-covalently with ankyrin, a 200 kDa cytoskeletal protein that attaches other cytoskeletal proteins to integral membrane proteins. GO:0030503 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0030503 GO:0005569 obsolete small nucleolar RNA biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005569 small nucleolar RNA OBSOLETE. (Was not defined before being made obsolete). GO:0030504 inorganic diphosphate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030504 Reactome:R-HSA-5226964 inorganic pyrophosphate transporter activity Enables the transfer of inorganic diphosphate across a membrane. GO:0030501 positive regulation of bone mineralization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030501 up-regulation of bone mineralization|upregulation of bone mineralization|up regulation of bone mineralization|activation of bone mineralization|stimulation of bone mineralization Any process that activates or increases the frequency, rate or extent of bone mineralization. GO:0005567 obsolete cytosolic ribosomal RNA biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005567 cytosolic ribosomal RNA OBSOLETE. (Was not defined before being made obsolete). GO:0030502 negative regulation of bone mineralization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030502 inhibition of bone mineralization|down regulation of bone mineralization|downregulation of bone mineralization|down-regulation of bone mineralization Any process that stops, prevents, or reduces the frequency, rate or extent of bone mineralization. GO:0005568 obsolete mitochondrial rRNA biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005568 mitochondrial rRNA OBSOLETE. (Was not defined before being made obsolete). GO:0005565 obsolete mitochondrial tRNA biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005565 mitochondrial tRNA OBSOLETE. (Was not defined before being made obsolete). GO:0005566 obsolete ribosomal RNA biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005566 ribosomal RNA OBSOLETE. (Was not defined before being made obsolete). GO:0030500 regulation of bone mineralization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030500 Any process that modulates the frequency, rate or extent of bone mineralization. GO:0005563 obsolete transfer RNA biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005563 transfer RNA OBSOLETE. (Was not defined before being made obsolete). GO:0005564 obsolete cytosolic tRNA biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005564 cytosolic tRNA OBSOLETE. (Was not defined before being made obsolete). GO:0005561 obsolete nucleic acid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005561 nucleic acid OBSOLETE. (Was not defined before being made obsolete). GO:0005562 obsolete RNA biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0005562 RNA OBSOLETE. (Was not defined before being made obsolete). GO:0030509 BMP signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0030509 dpp receptor signalling pathway|decapentaplegic receptor signalling pathway|decapentaplegic receptor signaling pathway|bone morphogenetic protein signalling pathway|decapentaplegic signaling pathway|BMP signalling pathway|dpp receptor signaling pathway|bone morphogenetic protein signaling pathway|dpp signaling pathway|BMP receptor signaling pathway A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0030507 spectrin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030507 Interacting selectively and non-covalently with spectrin, a protein that is the major constituent of the erythrocyte cytoskeletal network. It associates with band 4.1 (see band protein) and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. It is composed of nonhomologous chains, alpha and beta, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers. GO:0030508 obsolete thiol-disulfide exchange intermediate activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0030508 thiol-disulphide exchange intermediate activity|thiol-disulfide exchange intermediate activity|thioredoxin|glutaredoxin OBSOLETE. Functions as an exchange intermediate in thiol-disulfide exchange reactions. CHEBI:57770 trans-caffeate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57770 CHEBI:57771 UDP-N-acetyl-3-O-(1-carboxylatovinyl)-D-glucosamine(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57771 CHEBI:57778 triacetate lactone oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_57778 CHEBI:57779 tauropinate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57779 CHEBI:57776 N-acetyl-alpha-D-glucosamine 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57776 CHEBI:57777 1,4,5,6-tetrahydro-6-oxonicotinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57777 CHEBI:57774 2-acetyllactate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57774 CHEBI:57775 stipitaton-4-olate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57775 CHEBI:57772 N-acetyl-L-histidinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57772 CHEBI:57773 N-(carboxylatomethyl)-D-alanine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57773 GO:0005539 glycosaminoglycan binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0005539 Interacting selectively and non-covalently with any glycan (polysaccharide) containing a substantial proportion of aminomonosaccharide residues. CHEBI:18163 alpha-NeuNAc-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-NeuNAc-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18163 GO:0005536 glucose binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005536 Interacting selectively and non-covalently with the D- or L-enantiomer of glucose. GO:0005537 mannose binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0005537 Reactome:R-HSA-947991 mannose binding lectin Interacting selectively and non-covalently with mannose, a monosaccharide hexose, stereoisomeric with glucose, that occurs naturally only in polymerized forms called mannans. GO:0005534 galactose binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005534 galactose binding lectin Interacting selectively and non-covalently with the aldohexose galactose (galacto-hexose), a common constituent of many oligo- and polysaccharides. GO:0005532 obsolete mannose binding lectin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005532 mannose receptor|mannose binding lectin OBSOLETE. (Was not defined before being made obsolete). CHEBI:57769 precorrin-4(8-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57769 GO:0005533 obsolete N-acetylgalactosamine lectin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005533 N-acetylgalactosamine lectin OBSOLETE. (Was not defined before being made obsolete). GO:0005530 obsolete lectin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005530 lectin OBSOLETE. Lectins are proteins obtained particularly from the seeds of leguminous plants, but also from many other plant and animal sources, that have binding sites for specific mono or oligosaccharides in cell walls or membranes. They thereby change the physiology of the membrane to cause agglutination, mitosis, or other biochemical changes in the cell. GO:0005531 obsolete galactose binding lectin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005531 galactose binding lectin OBSOLETE. (Was not defined before being made obsolete). CHEBI:43120 (6R)-L-erythro-6,7-dihydrobiopterin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_43120 CHEBI:33792 canonical ribonucleoside residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33792 CHEBI:33793 canonical deoxyribonucleoside residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33793 CHEBI:57760 3-oxoglycyrrhetinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57760 CHEBI:33794 tRNA(fMet) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33794 CHEBI:33797 glucaric acid derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33797 CHEBI:33798 tetraric acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33798 CHEBI:43129 (+)-6a-hydroxymaackiain biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_43129 CHEBI:57767 mono(glucosyluronic acid)bilirubin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57767 CHEBI:18159 ribose 5-triphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18159 CHEBI:57768 4-coumaroylshikimate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57768 CHEBI:18157 aerobactin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18157 CHEBI:57766 3-(imidazol-4-yl)-2-oxopropyl phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57766 CHEBI:18155 (S)-1,2-didecanoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18155 CHEBI:57763 limonoate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57763 CHEBI:57764 1-deoxy-D-altro-heptulose 7-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57764 CHEBI:18153 ethene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18153 CHEBI:57761 pyridoxaminium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57761 CHEBI:18154 polysaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18154 CHEBI:57762 L-valine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57762 CHEBI:33791 canonical nucleoside residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33791 GO:0005549 odorant binding biolink:MolecularActivity go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0005549 Interacting selectively and non-covalently with an odorant, any substance capable of stimulating the sense of smell. CHEBI:18151 menaquinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18151 CHEBI:18152 myricetin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18152 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005547 PIP3 binding Interacting selectively and non-covalently with phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions. GO:0005548 phospholipid transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005548 Reactome:R-HSA-5678706|Reactome:R-HSA-216757|Reactome:R-HSA-5678749|Reactome:R-HSA-8857662|Reactome:R-HSA-8865637|Reactome:R-HSA-382553|Reactome:R-HSA-8867876 Enables the directed movement of phospholipids into, out of or within a cell, or between cells. Phospholipids are a class of lipids containing phosphoric acid as a mono- or diester. CHEBI:18150 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18150 GO:0005545 1-phosphatidylinositol binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005545 Interacting selectively and non-covalently with phosphatidylinositol, any glycophospholipid with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol. GO:0005546 phosphatidylinositol-4,5-bisphosphate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005546 PtdIns(4,5)P2 binding|PIP2 binding|1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate binding|phosphatidylinositol 4,5-bisphosphate binding Interacting selectively and non-covalently with phosphatidylinositol-4,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' and 5' positions. GO:0005543 phospholipid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005543 Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester. CHEBI:57758 N(3)-(carboxylatoformyl)-L-2,3-diaminopropionate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57758 GO:0005544 calcium-dependent phospholipid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005544 Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester, in the presence of calcium. CHEBI:57759 gossypetin-3-olate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_57759 GO:0005541 obsolete acyl-CoA or acyl binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005541 acyl-CoA or acyl binding OBSOLETE. Interacting selectively with acyl-CoA or acyl, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty acyl group, or any group formally derived by removal of a hydroxyl group from the acid function of an organic acid. GO:0005542 folic acid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005542 vitamin M binding|folate binding|vitamin B9 binding Interacting selectively and non-covalently with folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines. GO:0005540 hyaluronic acid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005540 hyaluronan binding Interacting selectively and non-covalently with hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine. CHEBI:5533 granaticin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_5533 CHEBI:57756 sphingosine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57756 CHEBI:18148 alpha-D-glucose 1,6-bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18148 CHEBI:18149 aureusidin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18149 CHEBI:57757 D-threonine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57757 CHEBI:18146 (R)-canadine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18146 CHEBI:57754 trans-5-O-caffeoyl-D-quinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57754 CHEBI:18147 beta-maltose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18147 CHEBI:57755 (R)-N-methylcoclaurinium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57755 CHEBI:18144 all-trans-nonaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18144 CHEBI:57752 (S)-3-(imidazol-5-yl)lactate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57752 CHEBI:18145 (+)-alpha-tocopherol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18145 CHEBI:57753 vindolinium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57753 CHEBI:57750 N(tele)-methyl-L-histidinium residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57750 CHEBI:18142 N(6')-acetylkanamycin B biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18142 CHEBI:5530 gramicidin S biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_5530 GO:0005516 calmodulin binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0005516 Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states. CHEBI:18184 3,5,3'-triiodothyropyruvic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18184 GOREL:0001019 results_in_division_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GOREL_0001019 GOREL:0001019 CHEBI:18185 gamma-tocopherol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18185 GO:0005517 obsolete calmodulin inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005517 calmodulin inhibitor activity OBSOLETE. This term was not defined before being made obsolete. GO:0005514 obsolete calcium ion storage activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005514 calcium ion storage activity OBSOLETE. (Was not defined before being made obsolete). GO:0005515 protein binding biolink:MolecularActivity go-plus goslim_chembl|goslim_candida|goslim_plant|goslim_pir|goslim_aspergillus|goslim_metagenomics http://purl.obolibrary.org/obo/GO_0005515 glycoprotein binding|protein amino acid binding Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). CHEBI:18183 5-oxo-L-proline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18183 GO:0005513 detection of calcium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0005513 calcium ion detection|detection of Ca2+ ion|Ca2+ ion detection|calcium ion sensing The series of events in which a calcium ion stimulus is received by a cell and converted into a molecular signal. CHEBI:57747 3-(pyrazol-1-yl)-L-alanine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57747 CHEBI:33778 galactonates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33778 CHEBI:33772 gluconic acid derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33772 CHEBI:57745 4-hydroxy-1-pyrroline-2-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57745 CHEBI:57746 3',5'-cyclic GMP(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57746 CHEBI:18179 phosphoinositide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18179 CHEBI:57743 L-citrulline zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57743 CHEBI:57744 2-(alpha-D-mannosyl)-3-phosphonatoglycerate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57744 CHEBI:18177 N-acetylphenylethylamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18177 CHEBI:57741 phenylethanolaminium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57741 CHEBI:57742 guanidinoacetic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57742 GO:0005518 collagen binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005518 Interacting selectively and non-covalently with collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%). CHEBI:57740 L-5-carboxylatomethylhydantoin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57740 GO:0005519 cytoskeletal regulatory protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005519 Interacting selectively and non-covalently with any protein involved in modulating the reorganization of the cytoskeleton. CHEBI:18176 2-coumaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18176 GO:0005527 macrolide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005527 Interacting selectively and non-covalently with a macrolide, any of a large group of structurally related antibiotics produced by Streptomyces species. GO:0005528 FK506 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005528 FK506-sensitive peptidyl-prolyl cis-trans isomerase Interacting selectively and non-covalently with the 23-membered macrolide lactone FK506. GO:0005525 GTP binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005525 Reactome:R-HSA-167429 Interacting selectively and non-covalently with GTP, guanosine triphosphate. CHEBI:18171 8-O-methylsterigmatocystin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18171 CHEBI:18172 fluoroacetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18172 CHEBI:57738 2-arylpropionate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57738 GO:0005523 tropomyosin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005523 Interacting selectively and non-covalently with tropomyosin, a protein associated with actin filaments both in cytoplasm and, in association with troponin, in the thin filament of striated muscle. GO:0005524 ATP binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005524 Reactome:R-HSA-265682 Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. CHEBI:18170 selenic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18170 CHEBI:57739 phosphatidate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57739 GO:0005521 lamin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005521 lamin/chromatin binding Interacting selectively and non-covalently with lamin; any of a group of intermediate-filament proteins that form the fibrous matrix on the inner surface of the nuclear envelope. CHEBI:57736 UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-L-lysine(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57736 GO:0005522 profilin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0005522 Interacting selectively and non-covalently with profilin, an actin-binding protein that forms a complex with G-actin and prevents it from polymerizing to form F-actin. CHEBI:57737 D-xylulose 5-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57737 GO:0005520 insulin-like growth factor binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0005520 IGF binding Interacting selectively and non-covalently with an insulin-like growth factor, any member of a group of polypeptides that are structurally homologous to insulin and share many of its biological activities, but are immunologically distinct from it. CHEBI:57734 alpha-D-hexose 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57734 CHEBI:57735 2-oxosuccinamate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57735 CHEBI:18168 2-oxophytanic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18168 CHEBI:57732 4-carboxylato-2-hydroxyhexa-2,4-dienedioate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57732 CHEBI:18169 1D-myo-inositol 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18169 CHEBI:57733 myo-inositol 1,3,4,5,6-pentakisphosphate(10-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57733 CHEBI:57730 2-hydroxy-4-nitrophenolate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57730 CHEBI:18167 alpha-maltose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18167 CHEBI:57731 (R)-3-aminoisobutyric acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57731 GO:0005529 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0005529 CHEBI:18164 (2S)-2-hydroxyphytanic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18164 CHEBI:18165 isopenicillin N biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18165 CHEBI:72447 2-deoxystreptamine(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72447 UBERON:0014621 cervical spinal cord ventral horn biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014621 cervical spinal cord anterior horn|cervical spinal cord ventral horn A ventral horn of spinal cord that is part of a cervical spinal cord. UBERON:0014620 cervical spinal cord dorsal horn biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014620 cervical spinal cord dorsal horn|cervical spinal cord posterior horn A dorsal horn of spinal cord that is part of a cervical spinal cord. UBERON:0014614 cervical spinal cord white matter biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014614 cervical spinal cord white matter A white matter of spinal cord that is part of a cervical spinal cord. UBERON:0014615 accessory nerve root biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014615 cranial part of the accessory nerve|pars vagalis of nervus accessorius|c11n|cranial portion of eleventh cranial nerve|bulbar part of accessory nerve|cranial part of accessory nerve|nerve XI (cranialis)|bulbar accessory nerve|radices craniales nervi accessorii|root of accessory nerve|cranial accessory nerve|internal branch of accessory nerve|accessory portion of spinal accessory nerve|accessory nerve root A nerve root that is part of a accessory XI nerve. CHEBI:72454 poly(ribitol phosphate) teichoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72454 CHEBI:72455 poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72455 UBERON:0014610 thoracic spinal cord ventral horn biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014610 thoracic spinal cord ventral horn|thoracic spinal cord anterior horn A ventral horn of spinal cord that is part of a thoracic spinal cord. UBERON:0014613 cervical spinal cord gray matter biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014613 cervical spinal cord gray matter A gray matter of spinal cord that is part of a cervical spinal cord. UBERON:0014609 thoracic spinal cord dorsal horn biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014609 thoracic spinal cord dorsal horn|thoracic spinal cord posterior horn A dorsal horn of spinal cord that is part of a thoracic spinal cord. CHEBI:72453 poly(glycerol phosphate) teichoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72453 GO:0000820 regulation of glutamine family amino acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000820 regulation of glutamine family amino acid metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline. GO:0048800 antennal morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048800 The process in which the anatomical structures of the antenna are generated and organized. GO:0048801 antennal joint morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048801 The process in which the anatomical structures of the antennal joint are generated and organized. GO:0048802 notum morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048802 The process in which the anatomical structures of the dorsal part of the body are generated and organized. CHEBI:23495 cyclopentanols biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23495 CHEBI:23493 cyclopentanes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23493 GO:0000829 inositol heptakisphosphate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000829 Reactome:R-HSA-1855194|Reactome:R-HSA-1855182|Reactome:R-HSA-1855157 Catalysis of the reaction: ATP + diphospho-1D-myo-inositol-pentakisphosphate = ADP + bis(diphospho)-1D-myo-inositol-tetrakisphosphate. The isomeric configurations of the diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) and bis(diphospho)-1D-myo-inositol-tetrakisphosphate (bis-PP-IP4) are unknown. GO:0000825 inositol tetrakisphosphate 6-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000825 Reactome:R-HSA-1855206|MetaCyc:RXN-7184 inositol 1,3,4,5-tetrakisphosphate 6-kinase activity|1D-myo-inositol-tetrakisphosphate 6-kinase activity Catalysis of the reaction: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP. GO:0048803 imaginal disc-derived male genitalia morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048803 male genital morphogenesis The process in which the anatomical structures of male genitalia are generated and organized from the genital imaginal disc. GO:0000826 obsolete inositol pyrophosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000826 inositol diphosphate synthase activity|inositol pyrophosphate synthase activity OBSOLETE. Catalysis of the phosphorylation of inositol phosphates which possess diphosphate bonds. GO:0048804 imaginal disc-derived female genitalia morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048804 female genital morphogenesis The process in which the anatomical structures of female genitalia are generated and organized from the genital disc. GO:0000827 inositol-1,3,4,5,6-pentakisphosphate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000827 EC:2.7.4.21|Reactome:R-HSA-1855181|Reactome:R-HSA-1855223 Catalysis of the reaction: ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + diphospho-1D-myo-inositol tetrakisphosphate. The isomeric configuration of diphospho-1D-myo-inositol tetrakisphosphate is unknown. GO:0048805 imaginal disc-derived genitalia morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048805 genital morphogenesis The process in which the anatomical structures of genitalia are generated and organized from the genital imaginal disc. GO:0000828 inositol hexakisphosphate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000828 Reactome:R-HSA-1855207|Reactome:R-HSA-1855227|Reactome:R-HSA-1855216 Catalysis of the reaction: ATP + 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate = ADP + diphospho-1D-myo-inositol-pentakisphosphate. The isomeric configuration of diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) is unknown. GO:0048806 genitalia development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048806 genital development The process whose specific outcome is the progression of the genitalia over time, from its formation to the mature structure. GO:0000821 regulation of arginine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000821 regulation of arginine metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving arginine, 2-amino-5-(carbamimidamido)pentanoic acid. GO:0048807 female genitalia morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048807 female genital morphogenesis The process in which the anatomical structures of female genitalia are generated and organized. GO:0000822 inositol hexakisphosphate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000822 InsP6 binding|IP6 binding Interacting selectively and non-covalently with inositol hexakisphosphate. GO:0048808 male genitalia morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048808 male genital morphogenesis The process in which the anatomical structures of male genitalia are generated and organized. GO:0000823 inositol-1,4,5-trisphosphate 6-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000823 MetaCyc:2.7.1.151-RXN|EC:2.7.1.151|KEGG_REACTION:R05800 inositol polyphosphate multikinase activity|ATP:1D-myo-inositol-1,4,5-trisphosphate 6-phosphotransferase activity|IpmK|inositol trisphosphate 6-kinase activity Catalysis of the reaction: D-myo-inositol 1,4,5-trisphosphate + ATP = D-myo-inositol 1,4,5,6-tetrakisphosphate + ADP + 2 H(+). GO:0048809 analia morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048809 The process in which the anatomical structures of analia are generated and organized. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is analia morphogenesis in Drosophila melanogaster. GO:0000824 inositol tetrakisphosphate 3-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000824 Reactome:R-HSA-1855185|RHEA:11856 inositol polyphosphate multikinase activity|inositol 1,4,5,6-tetrakisphosphate 3-kinase activity|IpmK|EC:2.7.1.151|1D-myo-inositol-tetrakisphosphate 3-kinase activity Catalysis of the reaction: ATP + 1D-myo-inositol 1,4,5,6-tetrakisphosphate = ADP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate. GO:0000830 inositol hexakisphosphate 4-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000830 Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 4-diphospho-1D-myo-inositol (1,2,3,5,6)pentakisphosphate. GO:0000831 inositol hexakisphosphate 6-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000831 Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 6-diphospho-1D-myo-inositol (1,2,3,4,5)pentakisphosphate. GO:0048810 female analia morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048810 The process in which the anatomical structures of the analia of the female are generated and organized. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is found in Drosophila melanogaster. GO:0048811 male analia morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048811 The process in which the anatomical structures of the analia of the male are generated and organized. The analia is the posterior-most vertral appendage that develops from the genital disc. GO:0048812 neuron projection morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048812 neurite morphogenesis|neurite biosynthesis|neurite growth|neurite formation The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites. GO:0048813 dendrite morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048813 The process in which the anatomical structures of a dendrite are generated and organized. GO:0048814 regulation of dendrite morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048814 Any process that modulates the frequency, rate or extent of dendrite morphogenesis. GO:0000836 Hrd1p ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000836 HRD1 ubiquitin ligase complex A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal and membrane domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p. In mammals, this complex contains the ubiquitin ligase HRD1 (Synoviolin) or AMFR (gp78). GO:0048815 hermaphrodite genitalia morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048815 The process in which the anatomical structures of hermaphrodite genitalia are generated and organized. GO:0000837 Doa10p ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000837 Ssm4p ubiquitin ligase complex A multiprotein complex that recognizes and ubiquitinates membrane proteins with misfolded cytosolic domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Ssm4p/Doa10p. GO:0000838 Hrd1p ubiquitin ligase ERAD-M complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000838 A multiprotein complex that recognizes and ubiquitinates proteins with misfolded membrane domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p. GO:0048816 ocellus morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048816 The process in which the anatomical structures of the ocellus are generated and organized. The ocellus is a simple visual organ of insects. GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000839 A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p. GO:0048817 negative regulation of hair follicle maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048817 downregulation of hair follicle maturation|down regulation of hair follicle maturation|inhibition of hair follicle maturation|down-regulation of hair follicle maturation Any process that stops, prevents, or reduces the frequency, rate or extent of hair follicle maturation. GO:0048818 positive regulation of hair follicle maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048818 upregulation of hair follicle maturation|stimulation of hair follicle maturation|activation of hair follicle maturation|up-regulation of hair follicle maturation|up regulation of hair follicle maturation Any process that activates or increases the frequency, rate or extent of hair follicle maturation. GO:0000832 inositol hexakisphosphate 5-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000832 RHEA:12793|EC:2.7.4.21|MetaCyc:2.7.1.152-RXN|KEGG_REACTION:R09087 ATP:1D-myo-inositol-hexakisphosphate 5-phosphotransferase activity Catalysis of the reaction: ATP + 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate = ADP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate. GO:0048819 regulation of hair follicle maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048819 Any process that modulates the frequency, rate or extent of hair follicle maturation. GO:0000833 inositol heptakisphosphate 4-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000833 IP7 4-kinase activity|diphosphoinositol-pentakisphosphate 4-kinase activity Catalysis of the reaction: ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = 4,5-bisdiphosphoinositol-1D-myoinositol (1,2,3,6)tetrakisphosphate. GO:0000834 inositol heptakisphosphate 6-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000834 Catalysis of the reaction: ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = 5,6-bisdiphosphoinositol-1D-myoinositol (1,2,3,4)tetrakisphosphate. GO:0000835 ER ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000835 A ubiquitin ligase complex found in the ER. GO:0048820 hair follicle maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048820 A developmental process, independent of morphogenetic (shape) change, that is required for a hair follicle to attain its fully functional state. GO:0048821 erythrocyte development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048821 RBC development|red blood cell development The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure. UBERON:0000017 exocrine pancreas biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000017 exocrine part of pancreas|exocrine component of pancreas|pars exocrina pancreatis|exocrine pancreas The part of the pancreas that is part of the exocrine system and which produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells [GO]. GO:0048822 enucleate erythrocyte development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048822 enucleate red blood cell development|enucleate RBC development The process aimed at the progression of an enucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. UBERON:0000018 compound eye biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000018 Komplexauge|faceted eye|adult compound eye|insect eye|zusammengesetztes Auge|Facettenauge A light sensing organ composed of ommatidia GO:0048823 nucleate erythrocyte development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048823 nucleate RBC development|nucleate red blood cell development The process aimed at the progression of a nucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. UBERON:0000019 camera-type eye biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000019 eye|vertebrate eye|orbital part of face|eyes|camera-type eye plus associated structures|orbital region|regio orbitalis An organ of sight that includes the camera-type eyeball and supporting structures such as the lacrimal apparatus, the conjunctiva, the eyelid. CHEBI:23478 cyclohexanedione biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23478 GO:0048824 pigment cell precursor differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048824 chromatophore precursor differentiation The process in which a relatively unspecialized cell acquires specialized features of a pigment cell precursor. CHEBI:23470 cyclohexadienol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23470 GO:0000807 Z chromosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000807 Wikipedia:ZW_sex-determination_system The sex chromosome present in both sexes of species in which the female is the heterogametic sex. Two copies of the Z chromosome are present in each somatic cell of males and one copy is present in females. GO:0000808 origin recognition complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0000808 Wikipedia:Origin_recognition_complex origin of replication recognition complex|ORC A multisubunit complex that is located at the replication origins of a chromosome. GO:0000809 cytoplasmic origin of replication recognition complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000809 cytoplasmic ORC|prokaryotic ORC A multisubunit complex that is located at the replication origins of a chromosome in the cytoplasm. UBERON:0000024 forelimb wing biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000024 Forelimb that is used to produce lift for flight through the air. GO:0048825 cotyledon development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048825 The process whose specific outcome is the progression of the cotyledon over time, from its formation to the mature structure. The cotyledon is the modified leaf (seed leaf), found as part of the embryo in plant seeds. It is involved in either storage or absorption of food reserves. Dicotyledonous seeds contain two cotyledons, while monocotyledonous seeds contain only one. The cotyledons may appear above ground and show photosynthetic activity in the seedling. GO:0000803 sex chromosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000803 A chromosome involved in sex determination. GO:0000804 W chromosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000804 Wikipedia:ZW_sex-determination_system The sex chromosome present in females of species in which the female is the heterogametic sex; generally, the sex chromosome that pairs with the Z chromosome in the heterogametic sex. The W chromosome is absent from the cells of males and present in one copy in the somatic cells of females. GO:0048826 cotyledon morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048826 The process in which the anatomical structures of the cotyledon are generated and organized. The cotyledon is the modified leaf (seed leaf), found as part of the embryo in plant seeds. It is involved in either storage or absorption of food reserves. Dicotyledonous seeds contain two cotyledons, while monocotyledonous seeds contain only one. The cotyledons may appear above ground and show photosynthetic activity in the seedling. UBERON:0000025 tube biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000025 duct|anatomical tube Any hollow cylindrical anatomical structure containing a lumen through which substances are transported. GO:0048827 phyllome development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048827 The process whose specific outcome is the progression of a phyllome over time, from its formation to the mature structure. A phyllome is a collective term for all the different types of leaves appearing on plants. UBERON:0000026 appendage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000026 extremity|appendages|extremitaet|limbs/digits/tail Major subdivision of an organism that protrudes from the body[DOS, CARO]. GO:0000805 X chromosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000805 Wikipedia:X_chromosome The sex chromosome present in both sexes of species in which the male is the heterogametic sex. Two copies of the X chromosome are present in each somatic cell of females and one copy is present in males. GO:0000806 Y chromosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000806 Wikipedia:Y_chromosome The sex chromosome present in males of species in which the male is the heterogametic sex; generally, the sex chromosome that pairs with the X chromosome in the heterogametic sex. The Y chromosome is absent from the cells of females and present in one copy in the somatic cells of males. GO:0048828 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048828 UBERON:0000020 sense organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000020 organ of sensory organ system|sensor|sensory organ|sensillum|sensory organ system organ|organ of sense organ system|organ of sensory system|Sinnesorgan|sense organ system organ|sensory system organ An organ that is capable of transducing sensory stimulus to the nervous system. GO:0048829 root cap development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048829 The process whose specific outcome is the progression of the root cap over time, from its formation to the mature structure. The root cap protects the root meristem from friction as the root grows through the soil. The cap is made up of a group of parenchyma cells which secrete a glycoprotein mucilage as a lubricant. GO:0000800 lateral element biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000800 axial element A proteinaceous core found between sister chromatids during meiotic prophase. UBERON:0000021 cutaneous appendage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000021 epidermal appendage|skin appendage|epidermal growth Anatomical projection that protrudes from the skin. Examples: hair, nail, feather, claw, hoof, horn, wattle, spur, beak, antler, bristle and some scales. OBA:VT0005388 respiratory system trait biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_VT0005388 The quality when measured in respiratory system. GO:0000801 central element biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000801 A structural unit of the synaptonemal complex found between the lateral elements. UBERON:0000023 wing biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000023 aliform appendage Appendage that is shaped in order to produce lift for flight through the air. GO:0000802 transverse filament biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000802 A structural unit of the synaptonemal complex that spans the regions between the lateral elements and connects them. GO:1902906 proteasome storage granule assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902906 PSG formation|PSG assembly|proteasome storage granule formation|sequestration of proteasome core complex in proteasome storage granule The aggregation, arrangement and bonding together of a set of components to form a proteasome storage granule. GO:1902907 proteasome storage granule disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902907 PSG disassembly The disaggregation of a proteasome storage granule into its constituent components. GO:1902904 negative regulation of supramolecular fiber organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902904 down regulation of fibril organisation|downregulation of fibril organisation|down regulation of fibril organization|downregulation of fibril organization|negative regulation of fibril organisation|down-regulation of fibril organisation|inhibition of fibril organisation|down-regulation of fibril organization|inhibition of fibril organization Any process that stops, prevents or reduces the frequency, rate or extent of fibril organization. GO:0048830 adventitious root development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048830 The process whose specific outcome is the progression of adventitious root over time, from its formation to the mature structure. Adventitious roots are post-embryonic roots that develop from the plant shoot. GO:1902905 positive regulation of supramolecular fiber organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902905 upregulation of fibril organization|activation of fibril organisation|up regulation of fibril organisation|positive regulation of fibril organisation|activation of fibril organization|up regulation of fibril organization|up-regulation of fibril organisation|up-regulation of fibril organization|upregulation of fibril organisation Any process that activates or increases the frequency, rate or extent of supramolecular fiber organization. GO:0048831 regulation of shoot system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048831 regulation of shoot development Any process that modulates the frequency, rate or extent of shoot development. UBERON:0000006 islet of Langerhans biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000006 islets of Langerhans|pancreatic islet|pancreatic insula|island of Langerhans|island of pancreas the clusters of hormone-producing cells that are scattered throughout the pancreas GO:1902902 negative regulation of autophagosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902902 inhibition of autophagic vacuole assembly|down regulation of autophagic vacuole formation|inhibition of PAS formation|downregulation of autophagosome biosynthesis|negative regulation of autophagic vacuole assembly|down-regulation of autophagosome formation|negative regulation of autophagosome formation|inhibition of autophagic vacuole formation|down regulation of autophagosome biosynthesis|down regulation of PAS formation|inhibition of autophagosome biosynthesis|downregulation of PAS formation|down regulation of autophagic vacuole assembly|inhibition of autophagosome formation|downregulation of autophagic vacuole assembly|negative regulation of autophagic vacuole formation|down-regulation of autophagic vacuole formation|down-regulation of PAS formation|negative regulation of PAS formation|down regulation of autophagosome formation|down-regulation of autophagic vacuole assembly|negative regulation of autophagosome biosynthesis|down-regulation of autophagosome biosynthesis|downregulation of autophagic vacuole formation|downregulation of autophagosome formation Any process that stops, prevents or reduces the frequency, rate or extent of autophagosome assembly. GO:0048832 specification of plant organ number biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048832 The regionalization process that modulates the quantity of a particular type of plant organ. UBERON:0000007 pituitary gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000007 pituitary body|Hp|glandula pituitaria|hypophysis cerebri|hypophysis|pituitary The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands [GO]. An endocrine gland located ventral to the diencephalon and derived from mixed neuroectodermal and non neuroectodermal origin [ZFIN]. GO:1902903 regulation of supramolecular fiber organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902903 regulation of fibril organisation Any process that modulates the frequency, rate or extent of supramolecular fiber organization. GO:0048833 specification of floral organ number biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048833 Any process that modulates the number of floral organs formed in a floral whorl. GO:1902900 gut granule assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902900 gut granule formation|gut granule biogenesis The aggregation, arrangement and bonding together of a set of components to form a gut granule. GO:0048834 specification of petal number biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048834 Any process that modulates the number of petals formed in a flower. GO:1902901 positive regulation of transcription from RNA polymerase II promoter involved in stress response to cadmium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902901 positive regulation of transcription from Pol II promoter involved in response to cadmium toxicity|upregulation of transcription from RNA polymerase II promoter involved in response to cadmium ion stress|up-regulation of global transcription from RNA polymerase II promoter involved in stress response to cadmium ion|up regulation of global transcription from RNA polymerase II promoter involved in response to cadmium toxicity|up-regulation of transcription from RNA polymerase II promoter involved in response to cadmium toxicity|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in response to cadmium ion stress|upregulation of global transcription from RNA polymerase II promoter involved in response to cadmium ion stress|positive regulation of transcription from Pol II promoter involved in response to cadmium ion stress|stimulation of transcription from RNA polymerase II promoter involved in response to cadmium toxicity|upregulation of transcription from RNA polymerase II promoter involved in stress response to cadmium ion|positive regulation of global transcription from Pol II promoter involved in response to cadmium toxicity|up-regulation of transcription from RNA polymerase II promoter involved in response to cadmium ion stress|activation of transcription from RNA polymerase II promoter involved in response to cadmium toxicity|activation of global transcription from RNA polymerase II promoter involved in response to cadmium toxicity|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in stress response to cadmium ion|upregulation of global transcription from RNA polymerase II promoter involved in stress response to cadmium ion|stimulation of transcription from RNA polymerase II promoter involved in response to cadmium ion stress|positive regulation of transcription from Pol II promoter involved in stress response to cadmium ion|stimulation of global transcription from RNA polymerase II promoter involved in response to cadmium ion stress|stimulation of global transcription from RNA polymerase II promoter involved in response to cadmium toxicity|up regulation of global transcription from RNA polymerase II promoter involved in response to cadmium ion stress|positive regulation of transcription from RNA polymerase II promoter involved in response to cadmium toxicity|activation of transcription from RNA polymerase II promoter involved in response to cadmium ion stress|up-regulation of global transcription from RNA polymerase II promoter involved in response to cadmium toxicity|up regulation of transcription from RNA polymerase II promoter involved in response to cadmium toxicity|up-regulation of transcription from RNA polymerase II promoter involved in stress response to cadmium ion|positive regulation of global transcription from Pol II promoter involved in response to cadmium ion stress|stimulation of transcription from RNA polymerase II promoter involved in stress response to cadmium ion|positive regulation of transcription from RNA polymerase II promoter involved in response to cadmium ion stress|activation of global transcription from RNA polymerase II promoter involved in response to cadmium ion stress|stimulation of global transcription from RNA polymerase II promoter involved in stress response to cadmium ion|up regulation of transcription from RNA polymerase II promoter involved in response to cadmium ion stress|up regulation of global transcription from RNA polymerase II promoter involved in stress response to cadmium ion|activation of transcription from RNA polymerase II promoter involved in stress response to cadmium ion|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in response to cadmium toxicity|upregulation of global transcription from RNA polymerase II promoter involved in response to cadmium toxicity|upregulation of transcription from RNA polymerase II promoter involved in response to cadmium toxicity|positive regulation of global transcription from Pol II promoter involved in stress response to cadmium ion|up-regulation of global transcription from RNA polymerase II promoter involved in response to cadmium ion stress|activation of global transcription from RNA polymerase II promoter involved in stress response to cadmium ion|up regulation of transcription from RNA polymerase II promoter involved in stress response to cadmium ion Any positive regulation of transcription from RNA polymerase II promoter that is involved in stress response to cadmium ion. GO:0048835 specification of decreased petal number biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048835 Any process that reduces the number of petals produced in a developing flower. UBERON:0000009 submucosa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000009 submucous layer|tunica submucosa|organ submucosa|submucosa of region of organ|submucosa of organ|region of submucosa|tela submucosa A layer of dense irregular connective tissue that lines organs and supports the mucosa, as well as joins the mucosa to the bulk of underlying smooth muscle. [WP,unvetted]. CHEBI:23480 cyclohexanols biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23480 CHEBI:23483 cyclohexenecarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23483 CHEBI:23482 cyclohexanones biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23482 GO:0000818 nuclear MIS12/MIND complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000818 Mtw1p Including Nnf1p-Nsl1p-Dsn1p complex|MIND complex A multiprotein kinetochore subcomplex that binds to centromeric chromatin and forms part of the inner kinetochore of a chromosome in the nucleus. It helps to recruit outer kinetochore subunits that will bind to microtubules. Nuclear localization arises in some organisms because the nuclear envelope is not broken down during mitosis. In S. cerevisiae, it consists of at least four proteins: Mtw1p, Nnf1p, Nsl1p, and Dsn1. GO:0000819 sister chromatid segregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000819 The cell cycle process in which sister chromatids are organized and then physically separated and apportioned to two or more sets. UBERON:0014649 white matter of medulla oblongata biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014649 substantia alba medullae oblongatae|white matter of medulla|white substance of medulla|medullary white matter A white matter that is part of a medulla oblongata. GO:0048836 specification of increased petal number biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048836 Any process that increases the number of petals produced in a developing flower. UBERON:0000013 sympathetic nervous system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000013 sympathetic nervous system|sympathetic part of autonomic division of nervous system|pars sympathica divisionis autonomici systematis nervosi|pars sympathica divisionis autonomici systematis nervosi The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter [GO]. GO:0000814 ESCRT II complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000814 endosomal sorting complex required for transport An endosomal sorting complex required for transport and functions downstream of ESCRT I complex. It consists of the class E vacuolar protein sorting (Vps) proteins and is required for the membrane recruitment of ESCRT III complex and binds to ubiquitinated cargoes. GO:0048837 sorocarp sorus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048837 sorocarp spore head morphogenesis|sorocarp sorus formation|sorocarp spore head formation The process whose specific outcome is the progression of the sorocarp sorus over time, from its formation to the mature structure. A sorocarp sorus is the spore containing structure of a sorocarp. UBERON:0000014 zone of skin biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000014 skin|region of skin|skin region|skin zone|portion of skin Any portion of the organ that covers that body and consists of a layer of epidermis and a layer of dermis. GO:0000815 ESCRT III complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000815 endosomal sorting complex required for transport An endosomal sorting complex required for transport. Consists of two soluble subcomplexes of highly charged coiled-coil proteins and is required for sorting and/or concentration of multivesicular body (MVB) cargoes. UBERON:0000015 non-material anatomical boundary biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000015 anatomical boundary A non-material anatomical entity of two dimensions. Anatomical boundaries are contiguous structures. GO:0048838 release of seed from dormancy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048838 The process in which the dormant state is broken in a seed. Dormancy is characterized by a suspension of physiological activity that can be reactivated upon release. GO:0000816 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000816 GO:0000817 COMA complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000817 Ctf19p-Okp1p-Mcm1p-Ame1p complex A multiprotein complex in yeast consisting of Ctf19p, Okp1p, Mcm21p, and Ame1p. This complex bridges the subunits that are in contact with centromeric DNA and the subunits bound to microtubules during kinetochore assembly. UBERON:0000016 endocrine pancreas biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000016 pars endocrina pancreatis|endocrine part of pancreas|islets of Langerhans part of pancreas|endocrine pancreas The part of the pancreas that is part of the endocrine system and is made up of islet cells, which produce insulin, glucagon and somatostatin. GO:0048839 inner ear development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048839 The process whose specific outcome is the progression of the inner ear over time, from its formation to the mature structure. GO:0000810 diacylglycerol diphosphate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000810 RHEA:27449|EC:3.1.3.81|MetaCyc:RXN-11277 diacylglycerol pyrophosphate phosphatase activity|DGPP phosphohydrolase activity|DGPP phosphatase activity Catalysis of the reaction: a 1,2-diacyl-sn-glycerol 3-diphosphate + H2O = a 1,2-diacyl-sn-glycerol 3-phosphate + phosphate. UBERON:0000010 peripheral nervous system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000010 PNS|pars peripherica|systema nervosum periphericum A major division of the nervous system that contains nerves which connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands. GO:0000811 GINS complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000811 Go, Ichi, Ni and San complex A heterotetrameric protein complex that associates with replication origins, where it is required for the initiation of DNA replication, and with replication forks. GO:0000812 Swr1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000812 SWR-C A multisubunit protein complex that is involved in chromatin remodeling. It is required for the incorporation of the histone variant H2AZ into chromatin. In S. cerevisiae, the complex contains Swr1p, a Swi2/Snf2-related ATPase, and 12 additional subunits. GO:1902908 regulation of melanosome transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902908 Any process that modulates the frequency, rate or extent of melanosome transport. UBERON:0000011 parasympathetic nervous system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000011 parasympathetic part of autonomic division of nervous system|PNS - parasympathetic|pars parasympathica divisionis autonomici systematis nervosi|pars parasympathica divisionis autonomici systematis nervosi The parasympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia[GO]. UBERON:0000012 somatic nervous system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000012 somatic part of peripheral nervous system|somatic nervous system, somatic division|PNS - somatic|somatic peripheral nervous system Part of peripheral nervous system that includes the somatic parts of the cranial and spinal nerves and their ganglia and the peripheral sensory receptors. GO:1902909 negative regulation of melanosome transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902909 down-regulation of melanosome transport|downregulation of melanosome transport|down regulation of melanosome transport|inhibition of melanosome transport Any process that stops, prevents or reduces the frequency, rate or extent of melanosome transport. GO:0000813 ESCRT I complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000813 endosomal sorting complex required for transport An endosomal sorting complex required for transport. It consists of the class E vacuolar protein sorting (Vps) proteins and interacts with ubiquitinated cargoes. GO:1902917 positive regulation of mating projection assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902917 up-regulation of mating projection assembly|activation of mating projection assembly|upregulation of mating projection biogenesis|up-regulation of mating projection biogenesis|up regulation of mating projection assembly|activation of mating projection biogenesis|positive regulation of mating projection biogenesis|upregulation of mating projection assembly|up regulation of mating projection biogenesis Any process that activates or increases the frequency, rate or extent of mating projection assembly. GO:1902918 poly(5-hydroxyvalerate) metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902918 poly(5-hydroxyvalerate) metabolism The chemical reactions and pathways involving poly(5-hydroxyvalerate). GO:0048840 otolith development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048840 The process whose specific outcome is the progression of the otolith over time, from its formation to the mature structure. GO:1902915 negative regulation of protein polyubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902915 down regulation of protein polyubiquitination|negative regulation of protein polyubiquitylation|down-regulation of protein polyubiquitylation|inhibition of protein polyubiquitination|negative regulation of protein polyubiquitinylation|down-regulation of protein polyubiquitinylation|inhibition of polyubiquitin|downregulation of protein polyubiquitylation|down regulation of protein polyubiquitylation|downregulation of protein polyubiquitinylation|inhibition of protein polyubiquitylation|down regulation of polyubiquitin|down regulation of protein polyubiquitinylation|down-regulation of protein polyubiquitination|inhibition of protein polyubiquitinylation|downregulation of polyubiquitin|downregulation of protein polyubiquitination|down-regulation of polyubiquitin|negative regulation of polyubiquitin Any process that stops, prevents or reduces the frequency, rate or extent of protein polyubiquitination. GO:0048841 regulation of axon extension involved in axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048841 Any process that modulates the frequency, rate or extent of axon extension involved in axon guidance. GO:0048842 positive regulation of axon extension involved in axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048842 stimulation of axon extension involved in axon guidance|up-regulation of axon extension involved in axon guidance|activation of axon extension involved in axon guidance|up regulation of axon extension involved in axon guidance|upregulation of axon extension involved in axon guidance Any process that activates, maintains or increases the frequency, rate or extent of axon extension involved in axon guidance. GO:1902916 positive regulation of protein polyubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902916 activation of protein polyubiquitinylation|upregulation of protein polyubiquitination|up-regulation of polyubiquitin|positive regulation of protein polyubiquitylation|up regulation of protein polyubiquitylation|positive regulation of protein polyubiquitinylation|up regulation of protein polyubiquitinylation|up-regulation of protein polyubiquitination|activation of protein polyubiquitination|upregulation of polyubiquitin|upregulation of protein polyubiquitylation|upregulation of protein polyubiquitinylation|up regulation of polyubiquitin|up regulation of protein polyubiquitination|positive regulation of polyubiquitin|up-regulation of protein polyubiquitylation|activation of protein polyubiquitylation|up-regulation of protein polyubiquitinylation|activation of polyubiquitin Any process that activates or increases the frequency, rate or extent of protein polyubiquitination. CHEBI:23453 cycloalkane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23453 GO:0048843 negative regulation of axon extension involved in axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048843 down-regulation of axon extension involved in axon guidance|downregulation of axon extension involved in axon guidance|down regulation of axon extension involved in axon guidance|inhibition of axon extension involved in axon guidance Any process that stops, prevents, or reduces the frequency, rate or extent of axon extension involved in axon guidance. GO:1902913 positive regulation of neuroepithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902913 activation of neuroepithelial cell differentiation|up-regulation of neuroepithelial cell differentiation|up regulation of neuroepithelial cell differentiation|upregulation of neuroepithelial cell differentiation Any process that activates or increases the frequency, rate or extent of neuroepithelial cell differentiation. GO:1902914 regulation of protein polyubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902914 regulation of protein polyubiquitylation|regulation of protein polyubiquitinylation|regulation of polyubiquitin Any process that modulates the frequency, rate or extent of protein polyubiquitination. GO:0048844 artery morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048844 arteriogenesis|arterial morphogenesis The process in which the anatomical structures of arterial blood vessels are generated and organized. Arteries are blood vessels that transport blood from the heart to the body and its organs. GO:1902911 protein kinase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902911 A protein complex which is capable of protein kinase activity. CHEBI:23456 cyclodextrin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23456 GO:0048845 venous blood vessel morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048845 venous morphogenesis|vein morphogenesis The process in which the anatomical structures of venous blood vessels are generated and organized. Veins are blood vessels that transport blood from the body and its organs to the heart. GO:0048846 axon extension involved in axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048846 The long distance growth of a single cell process, that is involved in the migration of an axon growth cone, where the migration is directed to a specific target site by a combination of attractive and repulsive cues. GO:1902912 pyruvate kinase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902912 A protein complex which is capable of pyruvate kinase activity. CHEBI:23457 cyclodiene organochlorine insecticide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23457 GO:1902910 positive regulation of melanosome transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902910 upregulation of melanosome transport|up-regulation of melanosome transport|activation of melanosome transport|up regulation of melanosome transport Any process that activates or increases the frequency, rate or extent of melanosome transport. CHEBI:23450 cyclitol phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23450 CHEBI:23451 cyclitol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23451 UBERON:0014636 thoracic spinal cord gray matter biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014636 thoracic spinal cord gray matter A gray matter of spinal cord that is part of a thoracic spinal cord. UBERON:0014637 thoracic spinal cord white matter biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014637 thoracic spinal cord white matter A white matter of spinal cord that is part of a thoracic spinal cord. UBERON:0014639 frontal sulcus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014639 frontal lobe sulci|frontal lobe sulcus A sulcus of brain that is part of a frontal cortex. GO:0048847 adenohypophysis formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048847 anterior pituitary gland biosynthesis|anterior pituitary gland formation|anterior pituitary biosynthesis|adenophysis formation|adenophysis biosynthesis|anterior pituitary formation The process that gives rise to adenohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus. UBERON:0000002 uterine cervix biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000002 cervical canal of uterus|cervix uteri|neck of uterus|cervix|cervix of uterus|canalis cervicis uteri|cervical canal|uterine cervix|caudal segment of uterus Lower, narrow portion of the uterus where it joins with the top end of the vagina. UBERON:0000003 naris biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000003 Orifice of the olfactory system. The naris is the route by which odorants enter the olfactory system[MAH]. GO:0048848 neurohypophysis morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048848 neurophysis morphogenesis|posterior pituitary gland morphogenesis|posterior pituitary morphogenesis The process in which the anatomical structures of the neurohypophysis are generated and organized. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation. GO:0048849 neurohypophysis formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048849 posterior pituitary gland biosynthesis|neurophysis biosynthesis|posterior pituitary formation|posterior pituitary biosynthesis|neurophysis formation|posterior pituitary gland formation The process that gives rise to neurohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation. UBERON:0000004 nose biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000004 peripheral olfactory organ|nasus|nose|proboscis|olfactory apparatus|nasal sac The olfactory organ of vertebrates, consisting of nares, olfactory epithelia and the structures and skeletal framework of the nasal cavity. UBERON:0000005 chemosensory organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000005 chemosensory sensory organ GO:1902919 poly(5-hydroxyvalerate) biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902919 poly(5-hydroxyvalerate) anabolism|poly(5-hydroxyvalerate) synthesis|poly(5-hydroxyvalerate) formation|poly(5-hydroxyvalerate) biosynthesis The chemical reactions and pathways resulting in the formation of poly(5-hydroxyvalerate). UBERON:0000000 processual entity biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000000 An occurrent [span:Occurrent] that exists in time by occurring or happening, has temporal parts and always involves and depends on some entity. GO:1902928 inulin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902928 inulin biosynthesis|inulin anabolism|inulin synthesis|inulin formation The chemical reactions and pathways resulting in the formation of inulin. GO:0048850 hypophysis morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048850 pituitary gland morphogenesis The process in which the anatomical structures of the hypophysis are generated and organized. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands. GO:0048851 hypophysis formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048851 pituitary gland formation|hypophysis biosynthesis|pituitary gland biosynthesis The process in which the anatomical structures of the hypophysis are generated and organized. The hypophysis is an endocrine gland that secretes hormones that regulate many other glands. GO:1902929 plasma membrane of growing cell tip biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902929 plasma membrane part of growing cell end|plasma membrane part of growing cell tip|growing cell tip plasma membrane part Any plasma membrane part that is part of a growing cell tip. CHEBI:23466 cyclohexadienecarboxylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23466 GO:1902926 inulin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902926 inulin metabolism The chemical reactions and pathways involving inulin. GO:0048852 diencephalon morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048852 The process in which the anatomical structures of the diencephalon are generated and organized. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex. GO:1902927 inulin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902927 inulin catabolism|inulin degradation|inulin breakdown The chemical reactions and pathways resulting in the breakdown of inulin. GO:0048853 forebrain morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048853 prosencephalon morphogenesis The process in which the anatomical structures of the forebrain are generated and organized. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions). GO:1902924 poly(hydroxyalkanoate) biosynthetic process from glucose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902924 poly(hydroxyalkanoate) biosynthesis from glucose|poly(hydroxyalkanoate) formation from glucose|poly(hydroxyalkanoate) synthesis from glucose|poly(hydroxyalkanoate) anabolism from glucose The chemical reactions and pathways resulting in the formation of poly(hydroxyalkanoate) from glucose. GO:0048854 brain morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048854 The process in which the anatomical structures of the brain are generated and organized. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). CHEBI:23469 cyclohexadienediol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23469 GO:1902925 poly(hydroxyalkanoate) biosynthetic process from fatty acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902925 poly(hydroxyalkanoate) anabolism from fatty acid|poly(hydroxyalkanoate) synthesis from fatty acid|poly(hydroxyalkanoate) formation from fatty acid|poly(hydroxyalkanoate) biosynthesis from fatty acid The chemical reactions and pathways resulting in the formation of poly(hydroxyalkanoate) from fatty acid. GO:0048855 adenohypophysis morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048855 adenophysis morphogenesis|anterior pituitary morphogenesis|anterior pituitary gland morphogenesis The process in which the anatomical structures of the adenohypophysis are generated and organized. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus. GO:1902922 poly(3-hydroxyvalerate) metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902922 poly(3-hydroxyvalerate) metabolism The chemical reactions and pathways involving poly(3-hydroxyvalerate). GO:0048856 anatomical structure development biolink:BiologicalProcess go-plus goslim_plant|goslim_generic|goslim_chembl http://purl.obolibrary.org/obo/GO_0048856 development of an anatomical structure The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. GO:0048857 neural nucleus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048857 The biological process whose specific outcome is the progression of a neural nucleus from its initial condition to its mature state. A neural nucleus is an anatomical structure consisting of a discrete aggregate of neuronal soma. GO:1902923 poly(3-hydroxyvalerate) biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902923 poly(3-hydroxyvalerate) anabolism|poly(3-hydroxyvalerate) biosynthesis|poly(3-hydroxyvalerate) synthesis|poly(3-hydroxyvalerate) formation The chemical reactions and pathways resulting in the formation of poly(3-hydroxyvalerate). CHEBI:23468 cyclohexadienecarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23468 GO:1902920 poly(hydroxyvalerate) metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902920 poly(hydroxyvalerate) metabolism The chemical reactions and pathways involving poly(hydroxyvalerate). GO:1902921 poly(hydroxyvalerate) biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902921 poly(hydroxyvalerate) anabolism|poly(hydroxyvalerate) synthesis|poly(hydroxyvalerate) formation|poly(hydroxyvalerate) biosynthesis The chemical reactions and pathways resulting in the formation of poly(hydroxyvalerate). UBERON:0014635 dorsal nerve root of cervical spinal cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014635 posterior nerve root of cervical spinal cord|dorsal nerve root of cervical spinal cord A dorsal root of spinal cord that overlaps a cervical spinal cord. GO:0048858 cell projection morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048858 The process in which the anatomical structures of a cell projection are generated and organized. GO:0048859 formation of anatomical boundary biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048859 The process in which the limits of an anatomical structure are generated. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. GO:0034217 ascospore wall chitin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034217 ascospore wall chitin biosynthesis|ascospore wall chitin anabolism|ascospore wall chitin synthesis|ascospore wall chitin formation The chemical reactions and pathways resulting in the formation of ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores. GO:0034218 ascospore wall chitin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034218 ascospore wall chitin metabolism The chemical reactions and pathways involving ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores. CHEBI:443725 fosmidomycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_443725 GO:0034219 carbohydrate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034219 transmembrane carbohydrate transport|carbohydrate membrane transport The process in which a carbohydrate is transported across a membrane. GO:0010248 establishment or maintenance of transmembrane electrochemical gradient biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010248 The directed movement of ions to establish or maintain an electrochemical gradient across a membrane by means of some agent such as a transporter or pore. GO:0010249 auxin conjugate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010249 auxin conjugate metabolism The chemical reactions and pathways involving auxin conjugates, a bound form of auxin. GO:0009260 ribonucleotide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009260 ribonucleotide biosynthesis|ribonucleotide anabolism|ribonucleotide synthesis|ribonucleotide formation The chemical reactions and pathways resulting in the formation of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. GO:0009261 ribonucleotide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009261 ribonucleotide catabolism|ribonucleotide degradation|ribonucleotide breakdown The chemical reactions and pathways resulting in the breakdown of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. GO:0009262 deoxyribonucleotide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009262 deoxyribonucleotide metabolism The chemical reactions and pathways involving a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. GO:0009263 deoxyribonucleotide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009263 deoxyribonucleotide anabolism|deoxyribonucleotide synthesis|deoxyribonucleotide formation|deoxyribonucleotide biosynthesis The chemical reactions and pathways resulting in the formation of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. GO:0009253 peptidoglycan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009253 murein catabolism|peptidoglycan degradation|murein catabolic process|peptidoglycan breakdown|peptidoglycan catabolism The chemical reactions and pathways resulting in the breakdown of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls. GO:0010242 oxygen evolving activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010242 EC:1.10.3.9|MetaCyc:PSII-RXN|MetaCyc:RXN0-5265|RHEA:36359 photosynthetic water oxidation Catalysis of the reaction: 2 H2O = O2 + 4 H+ + 4 e-. The evolution of oxygen from oxidizing water is carried out by the oxygen evolving complex in photosystem II of plants. P680+, the photochemically oxidized reaction-center chlorophyll of PSII, is a strong biological oxidant. The reduction potential of P680+ is more positive than that of water, and thus it can oxidize water to give O2 and H+ ions. The oxygen escapes as a gas while the H+ ions remain in solution inside the thylakoid vesicle. GO:0009254 peptidoglycan turnover biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009254 murein turnover The continual breakdown and regeneration of peptidoglycan required to maintain the cell wall. GO:0010243 response to organonitrogen compound biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010243 response to organic nitrogen Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond. GO:0034210 sterol deacetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034210 The removal of an acetyl group from a sterol molecule. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid. CHEBI:370252 xylitol 5-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_370252 GO:0009255 Entner-Doudoroff pathway through 6-phosphogluconate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009255 MetaCyc:ENTNER-DOUDOROFF-PWY-I A pathway that converts a carbohydrate to pyruvate and glyceraldehyde-3 phosphate by producing 6-phosphogluconate and then dehydrating it. GO:0010240 plastid pyruvate dehydrogenase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0010240 dehydrogenase complex Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). This complex is found in plant plastids and is distinct from the one found in mitochondria. GO:0034211 GTP-dependent protein kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034211 GTP dependent catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate. GO:0010241 ent-kaurene oxidation to kaurenoic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010241 ent-kaurene oxidation to kaurenoic acid by ent-kaurene oxidase|ent-kaurene oxidation to ent-kaurenoate|ent-kaurene oxidation to ent-kaur-16-en-19-oate The three successive oxidations of the 4-methyl group of ent-kaurene to form ent-kaur-16-en-19-oate, kaurenoic acid. This process may be carried out entirely by the enzyme ent-kaurene oxidase. GO:0034212 peptide N-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034212 Reactome:R-HSA-3371554 Catalysis of the acetylation of an amino acid residue of a peptide or protein, according to the reaction: acetyl-CoA + peptide = CoA + N-acetylpeptide. GO:0009256 10-formyltetrahydrofolate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009256 10-formyl-THF metabolic process|10-formyl-THF metabolism|10-formyltetrahydrofolate metabolism The chemical reactions and pathways involving 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate. GO:0009257 10-formyltetrahydrofolate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009257 MetaCyc:PWY-3841|MetaCyc:1CMET2-PWY 10-formyltetrahydrofolate anabolism|10-formyltetrahydrofolate synthesis|10-formyltetrahydrofolate formation|10-formyl-THF biosynthetic process|10-formyl-THF biosynthesis|10-formyltetrahydrofolate biosynthesis The chemical reactions and pathways resulting in the formation of 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate. GO:0010246 rhamnogalacturonan I biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010246 rhamnogalacturonan I synthesis|rhamnogalacturonan I formation|rhamnogalacturonan I biosynthesis|rhamnogalacturonan I anabolism The chemical reactions and pathways resulting in the formation of rhamnogalacturonan I component of pectin, a rhamnose-rich pectic polysaccharide. GO:0034213 quinolinate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034213 quinolinate degradation|quinolinate breakdown|quinolinate catabolism The chemical reactions and pathways resulting in the breakdown of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid. GO:0010247 detection of phosphate ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010247 phosphate ion sensing|phosphate ion detection|phosphate ion perception The series of events in which a phosphate ion stimulus is received by a cell and converted into a molecular signal. GO:0034214 protein hexamerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034214 protein hexamer biosynthesis|protein hexamer biosynthetic process|protein hexamer assembly|protein hexamer formation The formation of a protein hexamer, a macromolecular structure consisting of six noncovalently associated identical or nonidentical subunits. GO:0009258 10-formyltetrahydrofolate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009258 10-formyl-THF catabolic process|10-formyl-THF catabolism|10-formyltetrahydrofolate catabolism|10-formyltetrahydrofolate degradation|10-formyltetrahydrofolate breakdown The chemical reactions and pathways resulting in the breakdown of 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate. GO:0009259 ribonucleotide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009259 ribonucleotide metabolism The chemical reactions and pathways involving a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. GO:0034215 thiamine:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034215 thiamin:hydrogen symporter activity|thiamin:proton symporter activity|thiamine:hydrogen symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: thiamine(out) + H+(out) = thiamine(in) + H+(in). GO:0010244 response to low fluence blue light stimulus by blue low-fluence system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010244 response to low fluence blue light by blf system|response to low fluence blue light Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a low fluence blue light stimulus by the blue low-fluence system. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm. The blue low-fluence system responds to blue light at or below 0.1 micromols/m2. In certain species excitation of the blue low fluence system induces the transcription of a number of nuclear and plastid coded genes. GO:0034216 high-affinity thiamine:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034216 high-affinity thiamin:hydrogen symporter activity|high-affinity thiamin:proton symporter activity|high affinity thiamin:hydrogen symporter activity|high-affinity thiamine:hydrogen symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: thiamine(out) + H+(out) = thiamine(in) + H+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. CHEBI:1800 4-chloro-2-methylphenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_1800 GO:0010245 radial microtubular system formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010245 Formation of radial microtubular systems during male meiotic cytokinesis in plants. GO:0034206 enhanceosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034206 Wikipedia:Enhanceosome A protein-DNA complex formed by the association of a distinct set of general and specific transcription factors with a region of enhancer DNA. The cooperative assembly of an enhanceosome confers specificity of transcriptional regulation. GO:0034207 steroid acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034207 The addition of an acetyl group to a steroid molecule. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid. GO:0034208 steroid deacetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034208 The removal of an acetyl group from a steroid molecule. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid. GO:0010259 multicellular organism aging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010259 An aging process that has as participant a whole multicellular organism. Multicellular organism aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Multicellular organisms aging includes processes like cellular senescence and organ senescence, but is more inclusive. May precede death (GO:0016265) of an organism and may succeed developmental maturation (GO:0021700). GO:0034209 sterol acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034209 The addition of an acetyl group to a sterol molecule. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid. GO:0009270 response to humidity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009270 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a humidity stimulus, moisture in the atmosphere. GO:0009271 phage shock biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009271 A response by bacterial cells to a variety of stresses including filamentous phage infection, mislocalization of envelope proteins, extremes of temperature, osmolarity or ethanol concentration, and the presence of proton ionophores such as carbonylcyanide m-chlorophenylhydrazone (CCCP), that involves expression of the phage shock protein operon, and acts to protect the bacterial cells from damage. GO:0009272 fungal-type cell wall biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009272 chitin- and beta-glucan-containing cell wall biogenesis|fungal-type cell wall synthesis|fungal-type cell wall biosynthetic process|fungal-type cell wall formation|fungal-type cell wall anabolism A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a fungal-type cell wall. The fungal-type cell wall contains beta-glucan and may contain chitin. GO:0009273 peptidoglycan-based cell wall biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009273 cell wall biosynthetic process|cell wall anabolism|cell wall assembly|cell envelope biosynthetic process|cell envelope biosynthesis|cell wall synthesis|cell wall formation The chemical reactions and pathways resulting in the formation of the peptidoglycan-based cell wall. An example of this process is found in Escherichia coli. GO:0009274 peptidoglycan-based cell wall biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009274 envelope|murein sacculus|peptidoglycan A protective structure outside the cytoplasmic membrane composed of peptidoglycan (also known as murein), a molecule made up of a glycan (sugar) backbone of repetitively alternating N-acetylglucosamine and N-acetylmuramic acid with short, attached, cross-linked peptide chains containing unusual amino acids. An example of this component is found in Escherichia coli. GO:0009264 deoxyribonucleotide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009264 deoxyribonucleotide catabolism|deoxyribonucleotide degradation|deoxyribonucleotide breakdown The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. GO:0010253 UDP-rhamnose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010253 MetaCyc:PWY-3261 UDP-rhamnose synthesis|UDP-rhamnose formation|UDP-rhamnose biosynthesis|UDP-rhamnose anabolism The chemical reactions and pathways resulting in the formation of UDP-L-rhamnose, a substance composed of rhamnose in glycosidic linkage with uridine diphosphate. GO:0009265 2'-deoxyribonucleotide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009265 2'-deoxyribonucleotide formation|2'-deoxyribonucleotide anabolism|2'-deoxyribonucleotide biosynthesis|2'-deoxyribonucleotide synthesis The chemical reactions and pathways resulting in the formation of a 2'-deoxyribonucleotide, a compound consisting of 2'-deoxyribonucleoside (a base linked to a 2'-deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. GO:0010254 nectary development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010254 The process whose specific outcome is the progression of the floral nectaries over time, from its formation to the mature structure. GO:0034200 D,D-heptose 1,7-bisphosphate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034200 RHEA:28518|MetaCyc:RXN0-4361 Catalysis of the reaction: D-beta-D-heptose 1,7-bisphosphate + H2O = D-beta-D-heptose 1-phosphate + phosphate. GO:0009266 response to temperature stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009266 response to thermal stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus. GO:0010251 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010251 GO:0010252 auxin homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010252 A homeostatic process that maintains an endogenous steady-state concentration of primary auxin, or constant level of auxin in a biological system, by a number of biochemical processes including transport, biosynthesis, catabolism and conjugation. GO:0034201 response to oleic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034201 response to oleate Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oleic acid stimulus. GO:0009267 cellular response to starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009267 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment. GO:0034202 glycolipid floppase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034202 Reactome:R-HSA-4570573|Reactome:R-HSA-446212 glycolipid-translocating activity|glycolipid floppase activity (cytosolic to exoplasmic leaftlet)|ATP-dependent intramembrane glycolipid transporter activity|ATPase-coupled intramembrane glycolipid transporter activity Catalysis of the movement of a glycolipid from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP. GO:0009268 response to pH biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009268 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution. GO:0010257 NADH dehydrogenase complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010257 The aggregation, arrangement and bonding together of a set of components to form an NADH dehydrogenase complex. GO:0034203 glycolipid translocation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034203 The translocation, or flipping, of glycolipid molecules from one monolayer of a membrane bilayer to the opposite monolayer. GO:0010258 NADH dehydrogenase complex (plastoquinone) assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010258 The aggregation, arrangement and bonding together of a set of components to form NADH:plastoquinone dehydrogenase complex, which is involved in the non-photochemical reduction of plastoquinones, as well as the cyclic electron transport around photosystem I. GO:0009269 response to desiccation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009269 desiccation tolerance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desiccation stimulus, extreme dryness resulting from the prolonged deprivation of water. GO:0034204 lipid translocation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034204 intramembrane lipid transfer The translocation, or flipping, of lipid molecules from one monolayer of a membrane bilayer to the opposite monolayer. GO:0010255 glucose mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010255 glucose mediated signalling The process in which a change in the level of mono- and disaccharide glucose trigger the expression of genes controlling metabolic and developmental processes. GO:0034205 amyloid-beta formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034205 beta-amyloid polypeptide formation from amyloid precursor protein|beta-amyloid polypeptide formation from APP|beta-amyloid formation The generation of amyloid-beta by cleavage of the amyloid precursor protein (APP). GO:0010256 endomembrane system organization biolink:BiologicalProcess go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0010256 endomembrane system organisation|endomembrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system. GO:0010250 S-methylmethionine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010250 S-methylmethionine anabolism|S-methylmethionine synthesis|S-methylmethionine biosynthesis|S-methylmethionine formation The chemical reactions and pathways resulting in the formation of S-methyl-methionine (SMM) from methionine and S-adenosyl-methionine (Ado-Met), catalyzed by methionine S-methyltransferase (MMT). SMM can be reconverted to methionine by donating a methyl group to homocysteine, and concurrent operation of this reaction and that mediated by MMT sets up the SMM cycle. GO:0010228 vegetative to reproductive phase transition of meristem biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010228 transition from vegetative to reproductive phase|flowering|floral evocation The process involved in transforming a meristem that produces vegetative structures, such as leaves, into a meristem that produces reproductive structures, such as a flower or an inflorescence. GO:0010229 inflorescence development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010229 The process whose specific outcome is the progression of an inflorescence over time, from its formation to the mature structure. GO:0010226 response to lithium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010226 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lithium (Li+) ion stimulus. GO:0010227 floral organ abscission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010227 The controlled shedding of floral organs. GO:0009240 isopentenyl diphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009240 isopentenyl pyrophosphate biosynthesis|isopentenyl pyrophosphate biosynthetic process|isopentenyl diphosphate biosynthesis|isopentenyl diphosphate anabolism|isopentenyl diphosphate synthesis|isopentenyl diphosphate formation|IPP biosynthesis|IPP biosynthetic process The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, an isomer of dimethylallyl diphosphate and the key precursor of all isoprenoids. GO:0009241 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009241 GO:0010220 positive regulation of vernalization response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010220 up regulation of vernalization response|upregulation of vernalization response|stimulation of vernalization response|activation of vernalization response|up-regulation of vernalization response Any process that activates or induces the rate of the vernalization response, by which induction of flowering is normally caused by extended exposure to cold temperatures. GO:0009231 riboflavin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009231 Wikipedia:Riboflavin|MetaCyc:RIBOSYN2-PWY vitamin B2 biosynthetic process|vitamin B2 biosynthesis|riboflavin biosynthesis|riboflavin anabolism|riboflavin synthesis|riboflavin formation|vitamin G biosynthetic process|vitamin G biosynthesis The chemical reactions and pathways resulting in the formation of riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD). GO:0009232 riboflavin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009232 vitamin B2 catabolism|riboflavin catabolism|riboflavin degradation|riboflavin breakdown|vitamin B2 catabolic process|vitamin G catabolism|vitamin G catabolic process The chemical reactions and pathways resulting in the breakdown of riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD). GO:0010221 negative regulation of vernalization response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010221 downregulation of vernalization response|down regulation of vernalization response|inhibition of vernalization response|down-regulation of vernalization response Any process that stops, prevents or reduces the vernalization response, by which induction of flowering is normally caused by extended exposure to cold temperatures. GO:0009233 menaquinone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009233 multiprenylmenaquinone metabolism|menatetrenone metabolic process|menatetrenone metabolism|multiprenylmenaquinone metabolic process|vitamin K2 metabolic process|menaquinone metabolism|vitamin K2 metabolism The chemical reactions and pathways involving any of the menaquinones, quinone-derived compounds synthesized by intestinal bacteria. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones have vitamin K activity and are known as vitamin K2. GO:0009234 menaquinone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009234 MetaCyc:MENAQUINONESYN-PWY multiprenylmenaquinone biosynthetic process|multiprenylmenaquinone biosynthesis|menaquinone anabolism|menatetrenone biosynthetic process|menatetrenone biosynthesis|menaquinone synthesis|menaquinone formation|menaquinone biosynthesis|vitamin K2 biosynthetic process|vitamin K2 biosynthesis The chemical reactions and pathways resulting in the formation of any of the menaquinones. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones that have vitamin K activity and are known as vitamin K2. GO:0009235 cobalamin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009235 vitamin B12 metabolism|vitamin B12 reduction|vitamin B12 metabolic process|cobalamin metabolism The chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom. GO:0010224 response to UV-B biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010224 response to UVB light stimulus|response to UV-B light stimulus|response to UVB radiation stimulus|response to UV-B radiation stimulus|response to medium wave ultraviolet light stimulus|response to medium wave ultraviolet radiation stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm. GO:0010225 response to UV-C biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010225 response to germicidal ultraviolet radiation stimulus|response to shortwave ultraviolet light stimulus|response to UVC light stimulus|response to UV-C light stimulus|response to shortwave ultraviolet radiation stimulus|response to UVC radiation stimulus|response to UV-C radiation stimulus|response to germicidal ultraviolet light stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm. GO:0009236 cobalamin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009236 cobalamin anabolism|cobalamin synthesis|cobalamin formation|cobalamin biosynthesis|vitamin B12 biosynthetic process|vitamin B12 biosynthesis The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom. GO:0009237 siderophore metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009237 siderophore metabolism|siderochrome metabolism|siderochrome metabolic process The chemical reactions and pathways involving siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action. GO:0010222 stem vascular tissue pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010222 Vascular tissue pattern formation as it occurs in the stem of vascular plants. GO:0010223 secondary shoot formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010223 axillary shoot system formation|axillary shoot formation|shoot branching|auxiliary shoot formation The process that gives rise to secondary (or auxiliary or axillary) shoots in plants. This process pertains to the initial formation of a structure from unspecified parts. These secondary shoots originate from secondary meristems initiated in the axils of leaf primordia. Axillary meristems function like the shoot apical meristem of the primary shoot initating the development of lateral organs. GO:0009238 enterobactin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009238 enterochelin metabolic process|enterochelin metabolism|enterobactin metabolism The chemical reactions and pathways involving enterobactin, a catechol-derived siderochrome of Enterobacteria; enterobactin (N',N',N''-(2,6,10-trioxo-1,5,9-triacyclodecane-3,7,11-triyl)tris(2,3-dihydroxy)benzamide) is a self-triester of 2,3-dihydroxy-N-benzoyl-L-serine and a product of the shikimate pathway. GO:0009239 enterobactin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009239 MetaCyc:ENTBACSYN-PWY enterobactin biosynthetic process, peptide formation|enterobactin biosynthetic process, peptide modification|enterochelin biosynthesis|enterobactin anabolism|enterochelin biosynthetic process|enterobactin synthesis|enterobactin biosynthesis|enterobactin formation|enterobactin synthetase The chemical reactions and pathways resulting in the formation of enterobactin, a catechol-derived siderochrome of Enterobacteria; enterobactin (N',N',N''-(2,6,10-trioxo-1,5,9-triacyclodecane-3,7,11-triyl)tris(2,3-dihydroxy)benzamide) is a self-triester of 2,3-dihydroxy-N-benzoyl-L-serine and a product of the shikimate pathway. GO:0010239 chloroplast mRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010239 Steps involved in processing precursor RNAs arising from transcription of operons in the chloroplast genome into mature mRNAs. GO:0010237 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010237 GO:0010238 response to proline biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010238 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a proline stimulus. GO:0009250 glucan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009250 glucan biosynthesis|glucan anabolism|glucan synthesis|glucan formation The chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues. GO:0009251 glucan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009251 glucan degradation|glucan breakdown|glucan catabolism The chemical reactions and pathways resulting in the breakdown of glucans, polysaccharides consisting only of glucose residues. GO:0009252 peptidoglycan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009252 peptidoglycan anabolism|murein biosynthesis|murein biosynthetic process|peptidoglycan synthesis|peptidoglycan formation|peptidoglycan biosynthesis The chemical reactions and pathways resulting in the formation of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls. GO:0010231 maintenance of seed dormancy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010231 Any process that maintains a seed in a dormant state. GO:0009242 colanic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009242 MetaCyc:COLANSYN-PWY colanic acid biosynthesis|M antigen biosynthetic process|M antigen biosynthesis|colanic acid anabolism|colanic acid synthesis|colanic acid formation The chemical reactions and pathways resulting in the formation of colanic acid, a capsular bacterial polysaccharide. GO:0009243 O antigen biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009243 O antigen anabolism|O antigen synthesis|O antigen biosynthesis|O antigen formation The chemical reactions and pathways resulting in the formation of the O side chain of a lipopolysaccharide, which determines the antigenic specificity of the organism. It is made up of about 50 repeating units of a branched tetrasaccharide. GO:0010232 vascular transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010232 The directed movement of substances, into, out of or within a cell, either in a vascular tissue or in the vascular membrane. GO:0009244 lipopolysaccharide core region biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009244 lipopolysaccharide core region anabolism|lipopolysaccharide core region biosynthesis|lipopolysaccharide core region synthesis|lipopolysaccharide core region formation|LPS core region biosynthetic process The chemical reactions and pathways resulting in the formation of the core region of bacterial lipopolysaccharides, which contains ten saccharide residues. GO:0009245 lipid A biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009245 MetaCyc:NAGLIPASYN-PWY lipid A formation|lipid A biosynthesis|lipid A anabolism|lipid A synthesis The chemical reactions and pathways resulting in the formation of lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of four to six fatty acyl chains linked to two glucosamine residues. Further modifications of the backbone are common. GO:0010230 alternative respiration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010230 Alternative respiration pathway consumes oxygen, oxidizes NADH to NAD+ and generates water. During electron flow, proton motive force is diminished resulting in fewer molecules of ATP compared to cytochrome pathway. The pathway is found in plants, algae and some protozoa. GO:0010235 guard mother cell cytokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010235 guard mother cell division The stereotyped symmetric cell division by which guard mother cell give rise to stomatal guard cells. GO:0009246 enterobacterial common antigen biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009246 MetaCyc:ECASYN-PWY enterobacterial common antigen biosynthesis|enterobacterial common antigen anabolism|enterobacterial common antigen synthesis|enterobacterial common antigen formation The chemical reactions and pathways resulting in the formation of the enterobacterial common antigen, an acidic polysaccharide containing N-acetyl-D-glucosamine, N-acetyl-D-mannosaminouronic acid, and 4-acetamido-4,6-dideoxy-D-galactose. A major component of the cell wall outer membrane of Gram-negative bacteria. GO:0009247 glycolipid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009247 MetaCyc:PWY-401 glycolipid synthesis|glycolipid formation|glycolipid biosynthesis|glycolipid anabolism The chemical reactions and pathways resulting in the formation of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). GO:0010236 plastoquinone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010236 MetaCyc:PWY-1581 plastoquinone biosynthesis|plastoquinone anabolism|plastoquinone synthesis|plastoquinone formation The chemical reactions and pathways resulting in the formation of plastoquinone, a lipid-soluble electron-transporting coenzyme present in the chloroplast. GO:0010233 phloem transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010233 The directed movement of substances, into, out of or within the phloem during long distance transport between source and sink tissues. GO:0009248 K antigen biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009248 K antigen biosynthesis|K antigen anabolism|K antigen synthesis|K antigen formation The chemical reactions and pathways resulting in the formation of a K antigen, a capsular polysaccharide antigen carried on the surface of bacterial capsules that masks somatic (O) antigens. GO:0009249 protein lipoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009249 protein-lipoic acid cofactor linkage|peptidyl-lysine lipoylation The lipoylation of peptidyl-lysine to form peptidyl-N6-lipoyl-L-lysine. GO:0010234 anther wall tapetum cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010234 tapetal cell fate specification The process in which a cell becomes capable of differentiating autonomously into a tapetal cell of anthers in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. CHEBI:72405 lysophosphatidylserine 16:0(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72405 CHEBI:1845 4-hydroxy-3-polyprenylbenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_1845 GO:0010206 photosystem II repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010206 Proteolysis of the damaged D1 protein and re-assembly of a new D1 subunit in the photosystem II following photoinhibition. CHEBI:72408 lysophosphatidylserine 18:0(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72408 GO:0010207 photosystem II assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010207 The aggregation, arrangement and bonding together of a set of components to form a photosystem II complex on the thylakoid membrane. The photosystem II complex consists of at least 20 polypeptides and around 80 cofactors in most organisms. CHEBI:72409 lysophosphatidylserine 18:1(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72409 GO:0010204 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010204 GO:0010205 photoinhibition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010205 Wikipedia:Photoinhibition photosystem II inhibition The mechanism by which high light intensity inhibits photosynthesis through inactivation of the D1 protein of photosystem II. GO:0010208 pollen wall assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010208 pollen wall formation The formation of reticulate pollen wall pattern consisting of two layers, exine and intine. GO:0010209 vacuolar sorting signal binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010209 Interacting selectively and non-covalently with a vacuolar sorting signal, a specific peptide sequence that acts as a signal to localize the protein within the vacuole. GO:0009210 pyrimidine ribonucleoside triphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009210 pyrimidine ribonucleoside triphosphate degradation|pyrimidine ribonucleoside triphosphate catabolism|pyrimidine ribonucleoside triphosphate breakdown The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar. GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009211 pyrimidine deoxyribonucleoside triphosphate metabolism The chemical reactions and pathways involving pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar. GO:0009212 pyrimidine deoxyribonucleoside triphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009212 pyrimidine deoxyribonucleoside triphosphate biosynthesis|pyrimidine deoxyribonucleoside triphosphate anabolism|pyrimidine deoxyribonucleoside triphosphate synthesis|pyrimidine deoxyribonucleoside triphosphate formation The chemical reactions and pathways resulting in the formation of pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar. GO:0010202 response to low fluence red light stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010202 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low fluence red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Low fluence red light is defined in this case as short pulses of red light followed by darkness, providing a light level of 0.001-0.1 mmol/m2/sec. GO:0009213 pyrimidine deoxyribonucleoside triphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009213 pyrimidine deoxyribonucleoside triphosphate degradation|pyrimidine deoxyribonucleoside triphosphate catabolism|pyrimidine deoxyribonucleoside triphosphate breakdown The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar. GO:0010203 response to very low fluence red light stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010203 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low fluence red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Very low fluence red light is defined in this case as short pulses of red light followed by darkness, providing light levels of less than 0.001 mmol/m2/sec. GO:0009214 cyclic nucleotide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009214 cyclic nucleotide degradation|cyclic nucleotide breakdown|cyclic nucleotide catabolism The chemical reactions and pathways resulting in the breakdown of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue. OBO:GOCHE_51086 substance with chemical role role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_51086 GO:0010200 response to chitin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010200 A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus. GO:0009215 purine deoxyribonucleoside triphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009215 purine deoxyribonucleoside triphosphate metabolism The chemical reactions and pathways involving purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar. GO:0010201 response to continuous far red light stimulus by the high-irradiance response system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010201 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a continuous far red light stimulus by the high-irradiance response system. Far red light is electromagnetic radiation of wavelength 700-800nm. The activity of the high-irradiance response system is characterized by stronger effects of continuous than pulsed light at equal total fluence. GO:0009216 purine deoxyribonucleoside triphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009216 purine deoxyribonucleoside triphosphate anabolism|purine deoxyribonucleoside triphosphate biosynthesis|purine deoxyribonucleoside triphosphate synthesis|purine deoxyribonucleoside triphosphate formation The chemical reactions and pathways resulting in the formation of purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar. GO:0009217 purine deoxyribonucleoside triphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009217 purine deoxyribonucleoside triphosphate catabolism|purine deoxyribonucleoside triphosphate degradation|purine deoxyribonucleoside triphosphate breakdown The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar. GO:0009218 pyrimidine ribonucleotide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009218 pyrimidine ribonucleotide metabolism The chemical reactions and pathways involving a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. GO:0009219 pyrimidine deoxyribonucleotide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009219 pyrimidine deoxyribonucleotide metabolism The chemical reactions and pathways involving a pyrimidine deoxynucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. GO:0010217 cellular aluminum ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010217 cellular aluminium ion homeostasis Any process involved in the maintenance of an internal steady state of aluminum ions at the level of a cell. GO:0010218 response to far red light biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010218 response to far red light stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of far red light stimulus. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs. GO:0010215 cellulose microfibril organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010215 cellulose microfibril organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cellulose microfibril, any of the cellulose structures laid down in orthogonal layers in a plant cell wall. GO:0010216 maintenance of DNA methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010216 Any process involved in maintaining the methylation state of a nucleotide sequence. GO:0010219 regulation of vernalization response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010219 Any process that modulates the frequency, rate or extent of the vernalization response, by which induction of flowering is normally caused by extended exposure to cold temperatures. GO:0009230 thiamine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009230 vitamin B1 catabolism|thiamine catabolism|thiamine degradation|thiamin catabolic process|thiamine breakdown|vitamin B1 catabolic process The chemical reactions and pathways resulting in the breakdown of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver. GO:0009220 pyrimidine ribonucleotide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009220 MetaCyc:PWY0-162 pyrimidine ribonucleotide anabolism|pyrimidine ribonucleotide synthesis|pyrimidine ribonucleotide biosynthesis|pyrimidine ribonucleotide formation The chemical reactions and pathways resulting in the formation of a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. GO:0009221 pyrimidine deoxyribonucleotide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009221 MetaCyc:PWY0-166 pyrimidine deoxyribonucleotide anabolism|pyrimidine deoxyribonucleotide biosynthesis|pyrimidine deoxyribonucleotide synthesis|pyrimidine deoxyribonucleotide formation The chemical reactions and pathways resulting in the formation of a pyrimidine deoxyribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. GO:0010210 IAA-Phe conjugate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010210 Catalysis of the reaction: indole-3-acetyl-phenylalanine + H2O = indole-3-acetate + phenylalanine. GO:0009222 pyrimidine ribonucleotide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009222 pyrimidine ribonucleotide degradation|pyrimidine ribonucleotide breakdown|pyrimidine ribonucleotide catabolism The chemical reactions and pathways resulting in the breakdown of a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. GO:0009223 pyrimidine deoxyribonucleotide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009223 pyrimidine deoxyribonucleotide degradation|pyrimidine deoxyribonucleotide breakdown|pyrimidine deoxyribonucleotide catabolism The chemical reactions and pathways resulting in the breakdown of a pyrimidine deoxyribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. GO:0009224 CMP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009224 CMP biosynthesis|CMP anabolism|CMP synthesis|CMP formation The chemical reactions and pathways resulting in the formation of CMP, cytidine monophosphate. GO:0010213 non-photoreactive DNA repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010213 light-independent DNA repair A DNA repair process that is involved in repairing UV-induced DNA damage under non-photoreactivating conditions. The mechanism by which this repair process operates has not yet been completely elucidated. GO:0010214 seed coat development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010214 The process whose specific outcome is the progression of the seed coat over time, from its formation to the mature structure. GO:0009225 nucleotide-sugar metabolic process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0009225 nucleotide-sugar metabolism The cellular chemical reactions and pathways involving nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative. GO:0010211 IAA-Leu conjugate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010211 MetaCyc:RXN-2982 Catalysis of the reaction: indole-3-acetyl-leucine + H2O = indole-3-acetate + L-leucine. GO:0009226 nucleotide-sugar biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009226 nucleotide-sugar biosynthesis|nucleotide-sugar anabolism|nucleotide-sugar synthesis|nucleotide-sugar formation The chemical reactions and pathways resulting in the formation of nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative. GO:0009227 nucleotide-sugar catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009227 nucleotide-sugar degradation|nucleotide-sugar breakdown|nucleotide-sugar catabolism The chemical reactions and pathways resulting in the breakdown of nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative. GO:0010212 response to ionizing radiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010212 response to ionising radiation|response to ionizing radiation stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays. GO:0009228 thiamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009228 MetaCyc:THISYN-PWY thiamin biosynthetic process|thiamin anabolism|thiamine synthesis|thiamine formation|vitamin B1 biosynthetic process|vitamin B1 biosynthesis|thiamine biosynthesis The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver. GO:0009229 thiamine diphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009229 TPP biosynthetic process|TPP biosynthesis|thiamine pyrophosphate biosynthetic process|thiamine pyrophosphate biosynthesis|thiamine diphosphate biosynthesis|thiamin diphosphate biosynthetic process|thiamine diphosphate anabolism|thiamin pyrophosphate biosynthesis|thiamin pyrophosphate biosynthetic process|thiamine diphosphate synthesis|thiamine diphosphate formation The chemical reactions and pathways resulting in the formation of thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle. CHEBI:72423 phosphatidylcholine 26:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72423 CHEBI:72427 phosphatidylcholine 37:4 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72427 GO:0009200 deoxyribonucleoside triphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009200 deoxyribonucleoside triphosphate metabolism The chemical reactions and pathways involving a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar. GO:0009201 ribonucleoside triphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009201 ribonucleoside triphosphate anabolism|ribonucleoside triphosphate synthesis|ribonucleoside triphosphate formation|ribonucleoside triphosphate biosynthesis The chemical reactions and pathways resulting in the formation of a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar. GO:0009202 deoxyribonucleoside triphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009202 deoxyribonucleoside triphosphate anabolism|deoxyribonucleoside triphosphate synthesis|deoxyribonucleoside triphosphate formation|deoxyribonucleoside triphosphate biosynthesis The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar. GO:0009203 ribonucleoside triphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009203 ribonucleoside triphosphate degradation|ribonucleoside triphosphate breakdown|ribonucleoside triphosphate catabolism The chemical reactions and pathways resulting in the breakdown of a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar. GO:0009204 deoxyribonucleoside triphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009204 deoxyribonucleoside triphosphate catabolism|deoxyribonucleoside triphosphate degradation|deoxyribonucleoside triphosphate breakdown The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar. GO:0009205 purine ribonucleoside triphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009205 purine ribonucleoside triphosphate metabolism The chemical reactions and pathways involving purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar. GO:0009206 purine ribonucleoside triphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009206 purine ribonucleoside triphosphate anabolism|purine ribonucleoside triphosphate synthesis|purine ribonucleoside triphosphate formation|purine ribonucleoside triphosphate biosynthesis The chemical reactions and pathways resulting in the formation of purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar. GO:0009207 purine ribonucleoside triphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009207 purine ribonucleoside triphosphate catabolism|purine ribonucleoside triphosphate degradation|purine ribonucleoside triphosphate breakdown The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar. GO:0009208 pyrimidine ribonucleoside triphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009208 pyrimidine ribonucleoside triphosphate metabolism The chemical reactions and pathways involving pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar. GO:0009209 pyrimidine ribonucleoside triphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009209 pyrimidine ribonucleoside triphosphate synthesis|pyrimidine ribonucleoside triphosphate formation|pyrimidine ribonucleoside triphosphate biosynthesis|pyrimidine ribonucleoside triphosphate anabolism The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar. GO:0097751 spore-bearing structure formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097751 sporangium formation|sporophore formation The process of generating a spore-bearing structure. A spore-bearing structure is an anatomical structure that produces new spores. GO:0097752 regulation of DNA stability biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097752 Any process that modulates the stability of DNA. GO:0097750 endosome membrane tubulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097750 endosomal membrane tubulation A membrane tubulation process occurring in an endosome membrane. UBERON:2002260 premaxillary-maxillary joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_2002260 Joint that articulates the premaxilla and maxilla. Premaxillary-maxillary joint is paired. GO:1902898 fatty acid methyl ester metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902898 fatty acid methyl ester metabolism|FAME metabolic process The chemical reactions and pathways involving fatty acid methyl ester. GO:1902899 fatty acid methyl ester biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902899 fatty acid methyl ester biosynthesis|fatty acid methyl ester anabolism|FAME biosynthetic process|fatty acid methyl ester synthesis|fatty acid methyl ester formation The chemical reactions and pathways resulting in the formation of fatty acid methyl ester. GO:1902896 terminal web assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902896 terminal web formation The aggregation, arrangement and bonding together of a set of components to form a terminal web. GO:1902897 regulation of postsynaptic density protein 95 clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902897 regulation of PSD-95 clustering|regulation of post-synaptic density protein 95 clustering|regulation of Dlg4 clustering Any process that modulates the frequency, rate or extent of postsynaptic density protein 95 clustering. GO:1902894 negative regulation of pri-miRNA transcription by RNA polymerase II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902894 inhibition of pri-miRNA transcription from RNA polymerase II promoter|negative regulation of pri-miRNA transcription from RNA polymerase II promoter|down regulation of pri-miRNA transcription from RNA polymerase II promoter|downregulation of pri-miRNA transcription from RNA polymerase II promoter|down-regulation of pri-miRNA transcription from RNA polymerase II promoter Any process that stops, prevents or reduces the frequency, rate or extent of pri-miRNA transcription mediated by RNA polymerase II. GO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902895 up-regulation of pri-miRNA transcription from RNA polymerase II promoter|positive regulation of pri-miRNA transcription from RNA polymerase II promoter|upregulation of pri-miRNA transcription from RNA polymerase II promoter|up regulation of pri-miRNA transcription from RNA polymerase II promoter|activation of pri-miRNA transcription from RNA polymerase II promoter Any process that activates or increases the frequency, rate or extent of pri-miRNA transcription mediated by RNA polymerase II. GO:1902892 positive regulation of root hair elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902892 up-regulation of root hair elongation|activation of root hair elongation|up regulation of root hair elongation|upregulation of root hair elongation Any process that activates or increases the frequency, rate or extent of root hair elongation. GO:1902893 regulation of pri-miRNA transcription by RNA polymerase II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902893 regulation of pri-miRNA transcription from RNA polymerase II promoter Any process that modulates the frequency, rate or extent of pri-miRNA transcription mediated by RNA polymerase II. GO:0034176 negative regulation of toll-like receptor 12 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034176 negative regulation of toll-like receptor 12 signalling pathway|negative regulation of TLR12 signaling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 12 signaling pathway. GO:0034177 positive regulation of toll-like receptor 12 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034177 positive regulation of toll-like receptor 12 signalling pathway|positive regulation of TLR12 signaling pathway Any process that activates or increases the frequency, rate, or extent of toll-like receptor 12 signaling pathway. GO:0034178 toll-like receptor 13 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034178 toll-like receptor 13 signalling pathway|TLR13 signaling pathway Any series of molecular signals generated as a consequence of binding to toll-like receptor 13. CHEBI:1883 4-hydroxystyrene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_1883 GO:0034179 regulation of toll-like receptor 13 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034179 regulation of TLR13 signaling pathway|regulation of toll-like receptor 13 signalling pathway Any process that modulates the frequency, rate, or extent of toll-like receptor 13 signaling pathway. GO:0034170 toll-like receptor 11 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034170 TLR11 signaling pathway|toll-like receptor 11 signalling pathway Any series of molecular signals generated as a consequence of binding to toll-like receptor 11. GO:0034171 regulation of toll-like receptor 11 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034171 regulation of toll-like receptor 11 signalling pathway|regulation of TLR11 signaling pathway Any process that modulates the frequency, rate, or extent of toll-like receptor 11 signaling pathway. GO:0034172 negative regulation of toll-like receptor 11 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034172 negative regulation of toll-like receptor 11 signalling pathway|negative regulation of TLR11 signaling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 11 signaling pathway. GO:0097755 obsolete positive regulation of blood vessel diameter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097755 positive regulation of vasodilation OBSOLETE. Any process that increases the diameter of blood vessels. GO:0097756 obsolete negative regulation of blood vessel diameter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097756 negative regulation of vasodilation OBSOLETE. Any process that decreases the diameter of blood vessels. GO:0034173 positive regulation of toll-like receptor 11 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034173 positive regulation of toll-like receptor 11 signalling pathway|positive regulation of TLR11 signaling pathway Any process that activates or increases the frequency, rate, or extent of toll-like receptor 11 signaling pathway. GO:0034174 toll-like receptor 12 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034174 toll-like receptor 12 signalling pathway|TLR12 signaling pathway Any series of molecular signals generated as a consequence of binding to toll-like receptor 12. GO:0097753 membrane bending biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097753 membrane curvature A membrane organization process resulting in the bending of a membrane. GO:0097754 clathrin-mediated membrane bending biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097754 A membrane bending process mediated by clathrin. GO:0034175 regulation of toll-like receptor 12 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034175 regulation of toll-like receptor 12 signalling pathway|regulation of TLR12 signaling pathway Any process that modulates the frequency, rate, or extent of toll-like receptor 12 signaling pathway. GO:0034165 positive regulation of toll-like receptor 9 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034165 positive regulation of toll-like receptor 9 signalling pathway|positive regulation of TLR9 signaling pathway Any process that activates or increases the frequency, rate, or extent of toll-like receptor 9 signaling pathway. GO:0034166 toll-like receptor 10 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034166 TLR10 signaling pathway|toll-like receptor 10 signalling pathway Any series of molecular signals generated as a consequence of binding to toll-like receptor 10. GO:0034167 regulation of toll-like receptor 10 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034167 regulation of toll-like receptor 10 signalling pathway|regulation of TLR10 signaling pathway Any process that modulates the frequency, rate, or extent of toll-like receptor 10 signaling pathway. GO:0034168 negative regulation of toll-like receptor 10 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034168 negative regulation of TLR10 signaling pathway|negative regulation of toll-like receptor 10 signalling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 10 signaling pathway. CHEBI:1895 4-methylbenzyl alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_1895 GO:0034169 positive regulation of toll-like receptor 10 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034169 positive regulation of TLR10 signaling pathway|positive regulation of toll-like receptor 10 signalling pathway Any process that activates or increases the frequency, rate, or extent of toll-like receptor 10 signaling pathway. GO:0034160 negative regulation of toll-like receptor 8 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034160 negative regulation of TLR8 signaling pathway|negative regulation of toll-like receptor 8 signalling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 8 signaling pathway. GO:0034161 positive regulation of toll-like receptor 8 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034161 positive regulation of toll-like receptor 8 signalling pathway|positive regulation of TLR8 signaling pathway Any process that activates or increases the frequency, rate, or extent of toll-like receptor 8 signaling pathway. GO:0034162 toll-like receptor 9 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034162 TLR9 signaling pathway|toll-like receptor 9 signalling pathway Any series of molecular signals generated as a consequence of binding to toll-like receptor 9. GO:0034163 regulation of toll-like receptor 9 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034163 regulation of toll-like receptor 9 signalling pathway|regulation of TLR9 signaling pathway Any process that modulates the frequency, rate, or extent of toll-like receptor 9 signaling pathway. GO:0034164 negative regulation of toll-like receptor 9 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034164 negative regulation of TLR9 signaling pathway|negative regulation of toll-like receptor 9 signalling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 9 signaling pathway. GO:0097730 non-motile cilium biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097730 nonmotile primary cilia|sensory cilium|nonmotile primary cilium|immotile cilium|immotile primary cilium|nonmotile cilium A cilium which may have a variable array of axonemal microtubules but does not contain molecular motors. OBA:VT0005404 axon morphology trait biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_VT0005404 morphology of axon The morphology of a axon. GO:0010187 negative regulation of seed germination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010187 down-regulation of seed germination|downregulation of seed germination|down regulation of seed germination|inhibition of seed germination Any process that stops, prevents, or reduces the frequency, rate or extent of seed germination. GO:0034154 toll-like receptor 7 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034154 toll-like receptor 7 signalling pathway|TLR7 signaling pathway Any series of molecular signals generated as a consequence of binding to toll-like receptor 7. GO:0009198 pyrimidine deoxyribonucleoside diphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009198 pyrimidine deoxyribonucleoside diphosphate degradation|pyrimidine deoxyribonucleoside diphosphate catabolism|pyrimidine deoxyribonucleoside diphosphate breakdown The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxynucleoside diphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on the sugar. GO:0010188 response to microbial phytotoxin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010188 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a microbial phytotoxin stimulus. A microbial phytotoxin is a chemical substance produced by microbes which is toxic to plants. GO:0034155 regulation of toll-like receptor 7 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034155 regulation of TLR7 signaling pathway|regulation of toll-like receptor 7 signalling pathway Any process that modulates the frequency, rate, or extent of toll-like receptor 7 signaling pathway. GO:0009199 ribonucleoside triphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009199 ribonucleoside triphosphate metabolism The chemical reactions and pathways involving a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar. GO:0010185 regulation of cellular defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010185 regulation of cellular defence response Any process that modulates the frequency, rate or extent of cellular defense response. GO:0034156 negative regulation of toll-like receptor 7 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034156 negative regulation of toll-like receptor 7 signalling pathway|negative regulation of TLR7 signaling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 7 signaling pathway. GO:0010186 positive regulation of cellular defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010186 positive regulation of cellular defence response|upregulation of cellular defense response|up regulation of cellular defense response|activation of cellular defense response|stimulation of cellular defense response|up-regulation of cellular defense response Any process that activates or increases the frequency, rate or extent of cellular defense response. GO:0034157 positive regulation of toll-like receptor 7 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034157 positive regulation of TLR7 signaling pathway|positive regulation of toll-like receptor 7 signalling pathway Any process that activates or increases the frequency, rate, or extent of toll-like receptor 7 signaling pathway. GO:0034158 toll-like receptor 8 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034158 toll-like receptor 8 signalling pathway|TLR8 signaling pathway Any series of molecular signals generated as a consequence of binding to toll-like receptor 8. GO:0034159 regulation of toll-like receptor 8 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034159 regulation of TLR8 signaling pathway|regulation of toll-like receptor 8 signalling pathway Any process that modulates the frequency, rate, or extent of toll-like receptor 8 signaling pathway. GO:0010189 vitamin E biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010189 MetaCyc:PWY-1422 vitamin E anabolism|vitamin E synthesis|vitamin E formation|tocopherol biosynthetic process|tocopherol biosynthesis|alpha-tocopherol biosynthesis|alpha-tocopherol biosynthetic process|vitamin E biosynthesis The chemical reactions and pathways resulting in the formation of vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant. GO:0097739 negative regulation of ferrichrome biosynthetic process in response to iron biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097739 Any process that stops, prevents or reduces the rate of ferrichrome biosynthetic process in response to an iron stimulus. GO:0097737 acquisition of mycelium reproductive competence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097737 mycelium developmental competence A maturation process by which an organism acquires the ability to reproduce. In fungi, reproductive competence only occurs in a population of filamentous cells that form a mycelium. GO:0010180 thioglucosidase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010180 myrosinase binding Interacting selectively and non-covalently with the enzyme thioglucosidase. GO:0097738 substrate mycelium formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097738 The process by which, in some fungal species, hyphae grow as a network of invasive thread-like filaments formed from chains of attached cells within a solid or semi-solid substrate. GO:0097735 DIM/DIP cell wall layer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097735 A section of the Actinobacterium-type cell wall composed of (phenyl)phthiocerol, phthiodiolone, phthiotriol dimycocerosate, diphthioceranate and other compounds. GO:0097736 aerial mycelium formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097736 aerial hyphal growth|fertile mycelium formation The process by which hyphae grow in an upward or outward direction from the surface of the substrate; from there, propagative spores develop in or on characteristic structures that are distinctive of some fungal and bacterial species. The species that form an aerial mycelium develop conidiophores at the ends of the aerial hyphae. GO:0097733 photoreceptor cell cilium biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097733 photoreceptor cilium A specialised 9+0 non-motile cilium found in photoreceptor cells. A ciliary transition zone called 'photoreceptor connecting cilium' links the photoreceptor outer segment to the inner segment. GO:0034150 toll-like receptor 6 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034150 TLR6 signaling pathway|toll-like receptor 6 signalling pathway Any series of molecular signals generated as a consequence of binding to toll-like receptor 6. GO:0010183 pollen tube guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010183 The process in which the growth of pollen tube is directed towards the female gametophyte. GO:0034151 regulation of toll-like receptor 6 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034151 regulation of TLR6 signaling pathway|regulation of toll-like receptor 6 signalling pathway Any process that modulates the frequency, rate, or extent of toll-like receptor 6 signaling pathway. GO:0010184 cytokinin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010184 The directed movement of cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0097734 extracellular exosome biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097734 intraluminal vesicle assembly|exosome biogenesis|ILV assembly|exosome production|exosome assembly or secretion The assembly and secretion of an extracellular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. GO:0034152 negative regulation of toll-like receptor 6 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034152 negative regulation of TLR6 signaling pathway|negative regulation of toll-like receptor 6 signalling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 6 signaling pathway. GO:0010181 FMN binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010181 flavin mononucleotide binding Interacting selectively and non-covalently with flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes. GO:0097731 9+0 non-motile cilium biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097731 non-motile 9+0 cilium|9+0 immotile cilium|primary cilium A non-motile cilium where the axoneme has a ring of nine outer microtubule doublets but no central microtubules (and is therefore called a 9+0 axoneme). GO:0034153 positive regulation of toll-like receptor 6 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034153 positive regulation of TLR6 signaling pathway|positive regulation of toll-like receptor 6 signalling pathway Any process that activates or increases the frequency, rate, or extent of toll-like receptor 6 signaling pathway. GO:0097732 9+2 non-motile cilium biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097732 non-motile 9+2 cilium|9+2 immotile cilium A non-motile cilium where the axoneme has a ring of nine outer microtubule doublets plus two central microtubules (and is therefore called a 9+2 axoneme). GO:0010182 sugar mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010182 sugar mediated signalling The process in which a change in the level of a mono- or disaccharide such as glucose, fructose or sucrose triggers the expression of genes controlling metabolic and developmental processes. GO:0097740 paraflagellar rod biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097740 PFR A large lattice-like axial structure found in some flagellated protists which extends alongside the axoneme. Protein components of the paraflagellar rod are likely implicated, among other, in adenine nucleotide signalling and metabolism, and in calcium signalling. GO:0097741 mastigoneme biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097741 A hair-like structure covering the flagella found in some algae (heterokonts and cryptophytes). It is approximately 15 nm in diameter, and usually consist of a tubular shaft that itself terminates in smaller hairs. It is composed of glycoproteins and, likely, carbohydrates. Mastigonemes may assist in locomotion by increasing the surface area of a flagellum. GO:0034143 regulation of toll-like receptor 4 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034143 regulation of TLR4 signaling pathway|regulation of toll-like receptor 4 signalling pathway Any process that modulates the frequency, rate, or extent of toll-like receptor 4 signaling pathway. GO:0010198 synergid death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010198 synergid degeneration|synergid cell death Synergid cells undergo degeneration and death in response to penetration by the pollen tube. It is an active process that involves a dramatic decrease in cell volume, collapse of the vacuoles, and complete disintegration of the plasma membrane and most organelles. GO:0034144 negative regulation of toll-like receptor 4 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034144 negative regulation of toll-like receptor 4 signalling pathway|negative regulation of TLR4 signaling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 4 signaling pathway. GO:0010199 organ boundary specification between lateral organs and the meristem biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010199 The process in which boundaries between lateral organs and the meristem is established and maintained. GO:0034145 positive regulation of toll-like receptor 4 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034145 positive regulation of toll-like receptor 4 signalling pathway|positive regulation of TLR4 signaling pathway Any process that activates or increases the frequency, rate, or extent of toll-like receptor 4 signaling pathway. GO:0010196 nonphotochemical quenching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010196 The process by which excess light energy absorbed by chlorophyll and not used to drive photosynthesis is emitted as heat. This process helps maintain the balance between dissipation and utilization of light energy to minimize generation of oxidizing molecules, thereby protecting the plant against photo-oxidative damage. GO:0034146 toll-like receptor 5 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034146 toll-like receptor 5 signalling pathway|TLR5 signaling pathway Any series of molecular signals generated as a consequence of binding to toll-like receptor 5. GO:0010197 polar nucleus fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010197 The merging of the polar nuclei, the two nuclei contained within the same cell that are created from the mitotic division of the megaspore during angiosperm reproduction. Polar nuclear fusion takes place in the ovule, forming in the fusion nucleus and giving rise to the endosperm when fertilized. GO:0034147 regulation of toll-like receptor 5 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034147 regulation of TLR5 signaling pathway|regulation of toll-like receptor 5 signalling pathway Any process that modulates the frequency, rate, or extent of toll-like receptor 5 signaling pathway. GO:0034148 negative regulation of toll-like receptor 5 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034148 negative regulation of toll-like receptor 5 signalling pathway|negative regulation of TLR5 signaling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 5 signaling pathway. GO:0034149 positive regulation of toll-like receptor 5 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034149 positive regulation of toll-like receptor 5 signalling pathway|positive regulation of TLR5 signaling pathway Any process that activates or increases the frequency, rate, or extent of toll-like receptor 5 signaling pathway. GO:0097748 3'-5' RNA polymerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097748 RHEA:57528 Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template, via extension of the 5'-end. GO:0010190 cytochrome b6f complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010190 cytochrome b6f complex biogenesis Formation of cytochrome b6f complex, a complex that transfers electrons from reduced plastoquinone to oxidized plastocyanin and translocates protons from the stroma to the lumen, by the aggregation, arrangement and bonding together of its constituents. GO:0010191 mucilage metabolic process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0010191 mucilage metabolism The chemical reactions and pathways involving mucilage, a gelatinous substance secreted by plants. GO:0097749 membrane tubulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097749 A membrane organization process resulting in the formation of a tubular projection. This may face inwardly (as in tubular membrane invaginations) or outwardly (as in endosomal tubules). GO:0097746 blood vessel diameter maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097746 regulation of vasodilation|blood vessel diameter homeostasis|regulation of blood vessel diameter|regulation of vasodilatation|regulation of blood vessel size Any process that modulates the diameter of blood vessels. GO:0097747 RNA polymerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097747 Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template. GO:0097744 urate salt excretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097744 urate excretion The elimination by an organism of urate salt or uric acid. GO:0010194 obsolete microRNA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010194 microRNA metabolic process OBSOLETE. The chemical reactions and pathways involving microRNA, a large family of 21-22 nucleotide non-coding RNAs with presumed post-transcriptional regulatory activity. GO:0034140 negative regulation of toll-like receptor 3 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034140 negative regulation of toll-like receptor 3 signalling pathway|negative regulation of TLR3 signaling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 3 signaling pathway. GO:0010195 obsolete microRNA biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010195 microRNA anabolism|microRNA synthesis|microRNA formation|microRNA biosynthetic process|microRNA biosynthesis|miRNA biosynthetic process|miRNA biosynthesis OBSOLETE. The chemical reactions and pathways resulting in the formation of microRNA, a large family of 21-22 nucleotide non-coding RNAs with presumed post-transcriptional regulatory activity. GO:0097745 mitochondrial tRNA 5'-end processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097745 The process in which the 5' end of a pre-tRNA molecule is converted to that of a mature tRNA in the mitochondrion. GO:0034141 positive regulation of toll-like receptor 3 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034141 positive regulation of toll-like receptor 3 signalling pathway|positive regulation of TLR3 signaling pathway Any process that activates or increases the frequency, rate, or extent of toll-like receptor 3 signaling pathway. GO:0097742 de novo centriole assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097742 acentriolar basal body biogenesis|de novo ciliary basal body assembly|de novo basal body amplification|de novo basal body assembly|multiciliation|de novo centriole amplification|de novo basal body biogenesis|multiciliogenesis|de novo basal body generation Centriole assembly in which a centriole arises de novo, rather than by replication from an existing centriole. This process may occur via different mechanisms. Examples include the deuterosome pathway in multicilated epithelial animal cells and formation of centrioles during parthenogenesis in some insects. GO:0010192 mucilage biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010192 mucilage anabolism|mucilage synthesis|mucilage formation|mucilage biosynthesis The chemical reactions and pathways resulting in the formation of mucilage, a gelatinous substance secreted by plants. GO:0034142 toll-like receptor 4 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034142 toll-like receptor 4 signalling pathway|TLR4 signaling pathway Any series of molecular signals generated as a consequence of binding to toll-like receptor 4. GO:0010193 response to ozone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010193 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ozone stimulus. GO:0097743 de novo centriole assembly via blepharoplast biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097743 multiciliation|multiciliogenesis A de novo centriole assembly process observed in multi-ciliated sperm cells of some primitive land plants, and where centrioles are formed from a blepharoplast, ultimately giving rise to multiple cilia on the sperm surface. GO:0009180 purine ribonucleoside diphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009180 purine ribonucleoside diphosphate anabolism|purine ribonucleoside diphosphate biosynthesis|purine ribonucleoside diphosphate synthesis|purine ribonucleoside diphosphate formation The chemical reactions and pathways resulting in the formation of purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar. GO:0009181 purine ribonucleoside diphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009181 purine ribonucleoside diphosphate degradation|purine ribonucleoside diphosphate breakdown|purine ribonucleoside diphosphate catabolism The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar. GO:0009182 purine deoxyribonucleoside diphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009182 purine deoxyribonucleoside diphosphate metabolism The chemical reactions and pathways involving purine deoxyribonucleoside diphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with diphosphate on the sugar. GO:0009183 purine deoxyribonucleoside diphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009183 purine deoxyribonucleoside diphosphate synthesis|purine deoxyribonucleoside diphosphate formation|purine deoxyribonucleoside diphosphate biosynthesis|purine deoxyribonucleoside diphosphate anabolism The chemical reactions and pathways resulting in the formation of purine deoxyribonucleoside diphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with diphosphate on the sugar. GO:0009184 purine deoxyribonucleoside diphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009184 purine deoxyribonucleoside diphosphate catabolism|purine deoxyribonucleoside diphosphate degradation|purine deoxyribonucleoside diphosphate breakdown The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside diphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with diphosphate on the sugar. GO:0009185 ribonucleoside diphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009185 ribonucleoside diphosphate metabolism The chemical reactions and pathways involving a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar. GO:0009186 deoxyribonucleoside diphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009186 deoxyribonucleoside diphosphate metabolism The chemical reactions and pathways involving a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar. GO:0009176 pyrimidine deoxyribonucleoside monophosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009176 pyrimidine deoxyribonucleoside monophosphate metabolism The chemical reactions and pathways involving pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar. GO:0010165 response to X-ray biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010165 response to X-ray radiation stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz). GO:0034132 negative regulation of toll-like receptor 1 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034132 negative regulation of TLR1 signaling pathway|negative regulation of toll-like receptor 1 signalling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 1 signaling pathway. GO:0010166 wax metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010166 wax metabolism The chemical reactions and pathways involving wax, a compound containing C16 and C18 fatty acids. GO:0009177 pyrimidine deoxyribonucleoside monophosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009177 pyrimidine deoxyribonucleoside monophosphate biosynthesis|pyrimidine deoxyribonucleoside monophosphate anabolism|pyrimidine deoxyribonucleoside monophosphate synthesis|pyrimidine deoxyribonucleoside monophosphate formation The chemical reactions and pathways resulting in the formation of pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar. GO:0034133 positive regulation of toll-like receptor 1 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034133 positive regulation of TLR1 signaling pathway|positive regulation of toll-like receptor 1 signalling pathway Any process that activates or increases the frequency, rate, or extent of toll-like receptor 1 signaling pathway. GO:0034134 toll-like receptor 2 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034134 toll-like receptor 2 signalling pathway|TLR2 signaling pathway Any series of molecular signals generated as a consequence of binding to toll-like receptor 2. GO:0009178 pyrimidine deoxyribonucleoside monophosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009178 pyrimidine deoxyribonucleoside monophosphate catabolism|pyrimidine deoxyribonucleoside monophosphate breakdown|pyrimidine deoxyribonucleoside monophosphate degradation The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar. GO:0010163 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010163 GO:0010164 response to cesium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010164 response to cesium Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cesium stimulus. GO:0034135 regulation of toll-like receptor 2 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034135 regulation of toll-like receptor 2 signalling pathway|regulation of TLR2 signaling pathway Any process that modulates the frequency, rate, or extent of toll-like receptor 2 signaling pathway. GO:0009179 purine ribonucleoside diphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009179 purine ribonucleoside diphosphate metabolism The chemical reactions and pathways involving purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar. GO:0010169 thioglucosidase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0010169 myrosinase complex A large (200-800 kDa) multiprotein complex formed by 70-kDa and 5-kDa myrosinases, myrosinase- binding proteins (MBPs), MBP-related proteins and myrosinase-associated proteins. The complex has been identified in Brassica napus seeds. GO:0034136 negative regulation of toll-like receptor 2 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034136 negative regulation of TLR2 signaling pathway|negative regulation of toll-like receptor 2 signalling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 2 signaling pathway. GO:0034137 positive regulation of toll-like receptor 2 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034137 positive regulation of TLR2 signaling pathway|positive regulation of toll-like receptor 2 signalling pathway Any process that activates or increases the frequency, rate, or extent of toll-like receptor 2 signaling pathway. GO:0010167 response to nitrate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010167 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrate stimulus. GO:0034138 toll-like receptor 3 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034138 toll-like receptor 3 signalling pathway|TLR3 signaling pathway Any series of molecular signals generated as a consequence of binding to toll-like receptor 3. GO:0010168 ER body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0010168 endoplasmic reticulum body A novel compartment found in plant cells that is derived from the ER. The structures have a characteristic shape and size (10 mm long and 0.5 mm wide) and are surrounded with ribosomes. They have been found in Arabidopsis thaliana and related Brassicaceae species. GO:0034139 regulation of toll-like receptor 3 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034139 regulation of TLR3 signaling pathway|regulation of toll-like receptor 3 signalling pathway Any process that modulates the frequency, rate, or extent of toll-like receptor 3 signaling pathway. GO:0010161 red light signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010161 red light phototransduction|red light signalling pathway|red light signal transduction The series of molecular signals initiated upon sensing of red light by a photoreceptor molecule. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs. GO:0010162 seed dormancy process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010162 Wikipedia:Seed#Seed_dormancy_and_protection seed dormancy A dormancy process in which dormancy (sometimes called a dormant state) is induced, maintained or broken in a seed. Seed dormancy is a suspension of most physiological activity and growth in a seed, including the embryo contained therein, that can be reactivated. It often requires special conditions for reactivation, such as specific temperature, scarification, or leaching of inhibitors. GO:0034130 toll-like receptor 1 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034130 TLR1 signaling pathway|toll-like receptor 1 signalling pathway Any series of molecular signals generated as a consequence of binding to toll-like receptor 1. GO:0010160 formation of animal organ boundary biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010160 organ boundary specification The regionalization process that specifies animal organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues. GO:0034131 regulation of toll-like receptor 1 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034131 regulation of toll-like receptor 1 signalling pathway|regulation of TLR1 signaling pathway Any process that modulates the frequency, rate, or extent of toll-like receptor 1 signaling pathway. GO:0009190 cyclic nucleotide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009190 cyclic nucleotide anabolism|cyclic nucleotide synthesis|cyclic nucleotide formation|cyclic nucleotide biosynthesis The chemical reactions and pathways resulting in the formation of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue. GO:0034129 positive regulation of MyD88-independent toll-like receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034129 positive regulation of MyD88-independent TLR signaling pathway|positive regulation of MyD88-independent toll-like receptor|positive regulation of MyD88-independent toll-like receptor signalling pathway Any process that activates or increases the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway. GO:0009191 ribonucleoside diphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009191 ribonucleoside diphosphate breakdown|ribonucleoside diphosphate catabolism|ribonucleoside diphosphate degradation The chemical reactions and pathways resulting in the breakdown of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar. GO:0009192 deoxyribonucleoside diphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009192 deoxyribonucleoside diphosphate catabolism|deoxyribonucleoside diphosphate degradation|deoxyribonucleoside diphosphate breakdown The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar. GO:0009193 pyrimidine ribonucleoside diphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009193 pyrimidine ribonucleoside diphosphate metabolism The chemical reactions and pathways involving pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar. GO:0009194 pyrimidine ribonucleoside diphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009194 pyrimidine ribonucleoside diphosphate anabolism|pyrimidine ribonucleoside diphosphate synthesis|pyrimidine ribonucleoside diphosphate formation|pyrimidine ribonucleoside diphosphate biosynthesis The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar. GO:0009195 pyrimidine ribonucleoside diphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009195 pyrimidine ribonucleoside diphosphate degradation|pyrimidine ribonucleoside diphosphate catabolism|pyrimidine ribonucleoside diphosphate breakdown The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar. GO:0009196 pyrimidine deoxyribonucleoside diphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009196 pyrimidine deoxyribonucleoside diphosphate metabolism The chemical reactions and pathways involving pyrimidine deoxynucleoside diphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on the sugar. GO:0009197 pyrimidine deoxyribonucleoside diphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009197 pyrimidine deoxyribonucleoside diphosphate anabolism|pyrimidine deoxyribonucleoside diphosphate synthesis|pyrimidine deoxyribonucleoside diphosphate formation|pyrimidine deoxyribonucleoside diphosphate biosynthesis The chemical reactions and pathways resulting in the formation of pyrimidine deoxyribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on the sugar. GO:0009187 cyclic nucleotide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009187 cyclic nucleotide metabolism The chemical reactions and pathways involving a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue. GO:0034121 regulation of toll-like receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034121 regulation of TLR signaling pathway|regulation of toll-like receptor signalling pathway Any process that modulates the frequency, rate, or extent of toll-like receptor signaling pathway. GO:0010176 homogentisate phytyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010176 MetaCyc:RXN-2541|RHEA:37975|KEGG_REACTION:R07500 Catalysis of the reaction: homogentisate + phytyl diphosphate + H+ = 2-methyl-6-phytyl-1,4-benzoquinone + CO2 + diphosphate. 2-methyl-6-phytyl-1,4-benzoquinone is also known as 2-methyl-6-phytylplastoquinol. GO:0009188 ribonucleoside diphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009188 ribonucleoside diphosphate anabolism|ribonucleoside diphosphate synthesis|ribonucleoside diphosphate formation|ribonucleoside diphosphate biosynthesis The chemical reactions and pathways resulting in the formation of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar. GO:0034122 negative regulation of toll-like receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034122 negative regulation of TLR signaling pathway|negative regulation of toll-like receptor signalling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor signaling pathway. GO:0010177 2-(2'-methylthio)ethylmalate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010177 MetaCyc:RXN-2202|EC:2.3.3.17 methylthioalkylmalate synthase activity Catalysis of the reaction: 2-oxo-4-methylthiobutanoate + acetyl-CoA + H2O = 2-(2'-methylthio)ethylmalic-acid + coenzyme A + H+. GO:0010174 nucleoside transmembrane transporter activity, against a concentration gradient biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010174 concentrative nucleoside transporter activity Enables the transfer of a nucleoside, from one side of a membrane to the other, up a concentration gradient. GO:0034123 positive regulation of toll-like receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034123 positive regulation of TLR signaling pathway|positive regulation of toll-like receptor signalling pathway Any process that activates or increases the frequency, rate, or extent of toll-like receptor signaling pathway. GO:0009189 deoxyribonucleoside diphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009189 deoxyribonucleoside diphosphate anabolism|deoxyribonucleoside diphosphate synthesis|deoxyribonucleoside diphosphate biosynthesis|deoxyribonucleoside diphosphate formation The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar. GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034124 regulation ofMyD88-dependent toll-like receptor signalling pathway|regulation ofMyD88-dependent TLR signaling pathway Any process that modulates the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway. GO:0010175 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010175 GO:0034125 negative regulation of MyD88-dependent toll-like receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034125 negative regulation of MyD88-dependent TLR signaling pathway|negative regulation of MyD88-dependent toll-like receptor signalling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway. GO:0034126 positive regulation of MyD88-dependent toll-like receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034126 positive regulation of MyD88-dependent TLR signaling pathway|positive regulation of MyD88-dependent toll-like receptor signalling pathway Any process that activates or increases the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway. GO:0034127 regulation of MyD88-independent toll-like receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034127 regulation ofMyD88-independent TLR signaling pathway|regulation ofMyD88-independent toll-like receptor signalling pathway Any process that modulates the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway. GO:0010178 IAA-amino acid conjugate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010178 Catalysis of the cleavage of the amide bond between IAA (auxin) and the conjugated amino acid. GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034128 negative regulation of MyD88-independent TLR signaling pathway|negative regulation of MyD88-independent toll-like receptor signalling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway. GO:0010179 IAA-Ala conjugate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010179 MetaCyc:RXN-2981 Catalysis of the reaction: indole-3-acetyl-alanine + H2O = indole-3-acetate + L-alanine. GO:0010172 embryonic body morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010172 The process in which the anatomical structures of the embryonic soma are generated and organized. GO:0010173 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010173 GO:0010170 glucose-1-phosphate adenylyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0010170 Complex that catalyzes the synthesis of ADP-glucose and pyrophosphate from glucose-1-phosphate and ATP. In plants, the complex is a heterotetramer composed of two types of subunits (small and large). In bacteria, the enzyme complex is composed of four identical subunits. GO:0034120 positive regulation of erythrocyte aggregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034120 positive regulation of RBC aggregation|positive regulation of red blood cell aggregation Any process that activates or increases the frequency, rate, or extent of erythrocyte aggregation. GO:0010171 body morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010171 The process in which the anatomical structures of the soma are generated and organized. GO:0034118 regulation of erythrocyte aggregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034118 regulation of red blood cell aggregation|regulation of RBC aggregation Any process that modulates the frequency, rate, or extent of erythrocyte aggregation. GO:0034119 negative regulation of erythrocyte aggregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034119 negative regulation of red blood cell aggregation|negative regulation of RBC aggregation Any process that stops, prevents, or reduces the frequency, rate, or extent of erythrocyte aggregation. GO:0010149 obsolete senescence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010149 Wikipedia:Senescence senescence OBSOLETE. A preprogrammed process associated with the dismantling of an anatomical structure and an overall decline in metabolism. This may include the breakdown of organelles, membranes and other cellular components. An example of this process is found in Arabidopsis thaliana, when older leaves or floral organs are shed. GO:0009161 ribonucleoside monophosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009161 ribonucleoside monophosphate metabolism The chemical reactions and pathways involving a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar. GO:0009162 deoxyribonucleoside monophosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009162 deoxyribonucleoside monophosphate metabolism The chemical reactions and pathways involving a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar. GO:0009163 nucleoside biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009163 nucleoside anabolism|nucleoside synthesis|nucleoside formation|nucleoside biosynthesis The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside). GO:0009164 nucleoside catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009164 nucleoside catabolism|nucleoside degradation|nucleoside breakdown The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside). GO:0034110 regulation of homotypic cell-cell adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034110 Any process that modulates the frequency, rate, or extent of homotypic cell-cell adhesion. GO:0010143 cutin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010143 MetaCyc:PWY-321 cutin biosynthesis|cutin anabolism|cutin synthesis|cutin formation The chemical reactions and pathways resulting in the formation of cutin, a waxy substance, which combined with cellulose forms a substance nearly impervious to water and constituting the cuticle in plants. GO:0009154 purine ribonucleotide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009154 purine ribonucleotide catabolism|purine ribonucleotide degradation|purine ribonucleotide breakdown The chemical reactions and pathways resulting in the breakdown of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. GO:0009155 purine deoxyribonucleotide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009155 purine deoxyribonucleotide catabolism|purine deoxyribonucleotide breakdown|purine deoxyribonucleotide degradation The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. GO:0010144 pyridoxal phosphate biosynthetic process from pyridoxamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010144 pyridoxal 5'-phosphate salvage from pyridoxamine|pyridoxal phosphate anabolism from pyridoxamine|vitamin B6 biosynthesis from pyridoxamine|vitamin B6 biosynthetic process from pyridoxamine|pyridoxal phosphate synthesis from pyridoxamine|pyridoxal phosphate formation from pyridoxamine The chemical reactions and pathways resulting in the formation of pyridoxal phosphate, the active form of vitamin B6, from pyridoxamine. GO:0034111 negative regulation of homotypic cell-cell adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034111 Any process that stops, prevents, or reduces the frequency, rate, or extent of homotypic cell-cell adhesion. GO:0009156 ribonucleoside monophosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009156 ribonucleoside monophosphate biosynthesis|ribonucleoside monophosphate anabolism|ribonucleoside monophosphate synthesis|ribonucleoside monophosphate formation The chemical reactions and pathways resulting in the formation of a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar. GO:0010141 obsolete guanine, xanthine and their nucleoside salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010141 guanine, xanthine and their nucleoside salvage OBSOLETE. The pathway by which guanine, xanthine and their nucleoside from purine nucleotides breakdown are converted back to purine nucleotides. The pathway is important in cells where there is no de-novo purine nucleotides biosynthesis. GO:0034112 positive regulation of homotypic cell-cell adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034112 Any process that activates or increases the frequency, rate, or extent of homotypic cell-cell adhesion. GO:0010142 farnesyl diphosphate biosynthetic process, mevalonate pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010142 MetaCyc:PWY-922 farnesyl diphosphate anabolism, mevalonate pathway|Ac-MVA pathway|farnesyl diphosphate synthesis, mevalonate pathway|farnesyl diphosphate formation, mevalonate pathway|isoprenoid pathway|acetate-mevalonate pathway The pathway that converts acetate, in the form of acetyl-CoA, to farnesyl diphosphate (FPP) through a series of mevalonate intermediates. Farnesyl diphosphate is an important substrate for other essential pathways, such as biosynthesis of sterols. GO:0009157 deoxyribonucleoside monophosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009157 deoxyribonucleoside monophosphate anabolism|deoxyribonucleoside monophosphate synthesis|deoxyribonucleoside monophosphate formation|deoxyribonucleoside monophosphate biosynthesis The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar. GO:0034113 heterotypic cell-cell adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034113 The attachment of a cell to a cell of a different type via adhesion molecules. GO:0009158 ribonucleoside monophosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009158 ribonucleoside monophosphate degradation|ribonucleoside monophosphate breakdown|ribonucleoside monophosphate catabolism The chemical reactions and pathways resulting in the breakdown of a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar. GO:0034114 regulation of heterotypic cell-cell adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034114 Any process that modulates the frequency, rate, or extent of heterotypic cell-cell adhesion. GO:0010147 fructan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010147 MetaCyc:PWY-862 fructan degradation|fructan breakdown|fructan catabolism|levan catabolic process|levan catabolism The chemical reactions and pathways resulting in the breakdown of fructan, a polysaccharide consisting of fructose residues. GO:0009159 deoxyribonucleoside monophosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009159 deoxyribonucleoside monophosphate catabolism|deoxyribonucleoside monophosphate degradation|deoxyribonucleoside monophosphate breakdown The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar. GO:0010148 transpiration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010148 Wikipedia:Transpiration Release of water by the plant into the air as water vapor mainly through leaves. GO:0034115 negative regulation of heterotypic cell-cell adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034115 Any process that stops, prevents, or reduces the frequency, rate, or extent of heterotypic cell-cell adhesion. GO:0034116 positive regulation of heterotypic cell-cell adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034116 Any process that activates or increases the frequency, rate, or extent of heterotypic cell-cell adhesion. GO:0010145 fructan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010145 levan metabolic process|fructan metabolism The chemical reactions and pathways involving fructan, a polysaccharide consisting of fructose residues. GO:0034117 erythrocyte aggregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034117 RBC aggregation|red blood cell aggregation The adhesion of one erythrocyte to one or more other erythrocytes via adhesion molecules. GO:0010146 fructan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010146 MetaCyc:PWY-822 fructan biosynthesis|levan biosynthetic process|levan biosynthesis|fructan anabolism|fructan synthesis|fructan formation The chemical reactions and pathways resulting in the formation of fructan a polysaccharide consisting of fructose residues. GO:0010140 obsolete adenine, hypoxanthine and their nucleoside salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010140 adenine, hypoxanthine and their nucleoside salvage OBSOLETE. The pathway by which adenine, hypoxanthine and their nucleosides from purine nucleotides breakdown are converted back to purine nucleotides. The salvage pathway is important where there is no de-novo purine nucleotide biosynthesis. GO:0034107 negative regulation of erythrocyte clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034107 negative regulation of RBC clearance|negative regulation of red blood cell clearance|negative regulation of neocytolysis Any process that stops, prevents, or reduces the frequency, rate, or extent of erythrocyte clearance. GO:0034108 positive regulation of erythrocyte clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034108 positive regulation of neocytolysis|positive regulation of RBC clearance|positive regulation of red blood cell clearance Any process that activates or increases the frequency, rate, or extent of erythrocyte clearance. GO:0009170 purine deoxyribonucleoside monophosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009170 purine deoxyribonucleoside monophosphate metabolism The chemical reactions and pathways involving purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar. GO:0034109 homotypic cell-cell adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034109 The attachment of a cell to a second cell of the identical type via adhesion molecules. GO:0009171 purine deoxyribonucleoside monophosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009171 purine deoxyribonucleoside monophosphate anabolism|purine deoxyribonucleoside monophosphate synthesis|purine deoxyribonucleoside monophosphate formation|purine deoxyribonucleoside monophosphate biosynthesis The chemical reactions and pathways resulting in the formation of purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar. GO:0009172 purine deoxyribonucleoside monophosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009172 purine deoxyribonucleoside monophosphate breakdown|purine deoxyribonucleoside monophosphate catabolism|purine deoxyribonucleoside monophosphate degradation The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar. GO:0009173 pyrimidine ribonucleoside monophosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009173 pyrimidine ribonucleoside monophosphate metabolism The chemical reactions and pathways involving pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar. GO:0009174 pyrimidine ribonucleoside monophosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009174 pyrimidine ribonucleoside monophosphate biosynthesis|pyrimidine ribonucleoside monophosphate anabolism|pyrimidine ribonucleoside monophosphate synthesis|pyrimidine ribonucleoside monophosphate formation The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar. GO:0009175 pyrimidine ribonucleoside monophosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009175 pyrimidine ribonucleoside monophosphate catabolism|pyrimidine ribonucleoside monophosphate degradation|pyrimidine ribonucleoside monophosphate breakdown The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar. GO:0009165 nucleotide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009165 nucleotide anabolism|nucleotide synthesis|nucleotide formation|nucleotide biosynthesis The chemical reactions and pathways resulting in the formation of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates). GO:0010154 fruit development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010154 The process whose specific outcome is the progression of the fruit over time, from its formation to the mature structure. The fruit is a reproductive body of a seed plant. GO:0010155 regulation of proton transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010155 Any process that modulates the frequency, rate or extent of proton transport into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0009166 nucleotide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009166 nucleotide catabolism|nucleotide degradation|nucleotide breakdown The chemical reactions and pathways resulting in the breakdown of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates). GO:0034100 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0034100 GO:0010152 pollen maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010152 The final stages of microgametogenesis after the trinucleate stage has been reached resulting in viable pollen grains. GO:0034101 erythrocyte homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034101 red blood cell homeostasis|RBC homeostasis Any process of regulating the production and elimination of erythrocytes within an organism. GO:0009167 purine ribonucleoside monophosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009167 purine ribonucleoside monophosphate metabolism The chemical reactions and pathways involving purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar. GO:0010153 obsolete polar cell elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010153 polarity-dependent cell elongation|polar cell elongation OBSOLETE. Cell expansion that results in an increase in cell size along the axis of an organ in a polarized fashion. GO:0034102 erythrocyte clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034102 red blood cell clearance|RBC clearance|neocytolysis The selective elimination of erythrocytes from the body by autoregulatory mechanisms. GO:0009168 purine ribonucleoside monophosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009168 purine ribonucleoside monophosphate anabolism|purine ribonucleoside monophosphate synthesis|purine ribonucleoside monophosphate biosynthesis|purine ribonucleoside monophosphate formation The chemical reactions and pathways resulting in the formation of purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar. GO:0034103 regulation of tissue remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034103 Any process that modulates the frequency, rate, or extent of tissue remodeling. GO:0009169 purine ribonucleoside monophosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009169 purine ribonucleoside monophosphate degradation|purine ribonucleoside monophosphate breakdown|purine ribonucleoside monophosphate catabolism The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar. GO:0010158 abaxial cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010158 The process in which a cell becomes capable of differentiating autonomously into an abaxial cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. GO:0034104 negative regulation of tissue remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034104 Any process that stops, prevents, or reduces the frequency, rate, or extent of tissue remodeling. GO:0010159 specification of animal organ position biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010159 The regionalization process in which information that determines the correct position at which animal organ primordia are formed is generated and perceived resulting in correct positioning of the new animal organ. GO:0034105 positive regulation of tissue remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034105 Any process that activates or increases the frequency, rate, or extent of tissue remodeling. GO:0010156 obsolete sporocyte morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010156 sporocyte morphogenesis OBSOLETE. Formation and development of sporocyte, the haploid spores of angiosperms which are initiated by the differentiation of a subset of floral cells into sporocytes, which then undergo meiotic divisions to form microspores and megaspores. GO:0034106 regulation of erythrocyte clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034106 regulation of red blood cell clearance|regulation of neocytolysis|regulation of RBC clearance Any process that modulates the frequency, rate, or extent of erythrocyte clearance. GO:0010157 response to chlorate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010157 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chlorate stimulus. GO:0010150 leaf senescence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010150 The process that occurs in a leaf near the end of its active life that is associated with the dismantling of cell components and membranes, loss of functional chloroplasts, and an overall decline in metabolism. GO:0010151 chloroplast elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010151 Expansion of the chloroplast that usually precedes division. GO:0048740 obsolete striated muscle fiber development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048740 myogenesis|striated muscle fibre development|striated muscle fiber development OBSOLETE. The process whose specific outcome is the amplification and progression of myoblasts (muscle precursor cells) into terminally differentiated multinucleated muscle fibers. GO:1902818 ethyl acetate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902818 ethyl ethanoate metabolic process|ethyl acetate metabolism The chemical reactions and pathways involving ethyl acetate. GO:1902819 ethyl acetate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902819 ethyl ethanoate biosynthetic process|ethyl acetate anabolism|ethyl acetate synthesis|ethyl acetate biosynthesis|ethyl acetate formation The chemical reactions and pathways resulting in the formation of ethyl acetate. GO:0048741 skeletal muscle fiber development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048741 skeletal muscle fibre development|skeletal myofibre development|skeletal myofiber development The process whose specific outcome is the progression of the skeletal muscle fiber over time, from its formation to the mature structure. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast. GO:0048742 regulation of skeletal muscle fiber development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048742 regulation of skeletal myofibre development|regulation of skeletal myofiber development|regulation of skeletal muscle fibre development Any process that modulates the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast. GO:1902816 regulation of protein localization to microtubule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902816 regulation of protein localisation to microtubule Any process that modulates the frequency, rate or extent of protein localization to microtubule. GO:1902817 negative regulation of protein localization to microtubule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902817 inhibition of protein localisation to microtubule|down regulation of protein localization to microtubule|downregulation of protein localization to microtubule|down regulation of protein localisation to microtubule|downregulation of protein localisation to microtubule|down-regulation of protein localization to microtubule|inhibition of protein localization to microtubule|down-regulation of protein localisation to microtubule|negative regulation of protein localisation to microtubule Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to microtubule. GO:0048743 positive regulation of skeletal muscle fiber development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048743 up regulation of skeletal muscle fiber development|activation of skeletal muscle fiber development|stimulation of skeletal muscle fiber development|up-regulation of skeletal muscle fiber development|positive regulation of skeletal myofibre development|upregulation of skeletal muscle fiber development|positive regulation of skeletal myofiber development|positive regulation of skeletal muscle fibre development Any process that activates, maintains or increases the rate of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast. GO:1902814 positive regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902814 activation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry|activation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|positive regulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|up-regulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|up-regulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|up regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry|upregulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|upregulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|up regulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|upregulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry|activation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|positive regulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|up regulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|up-regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry Any process that activates or increases the frequency, rate or extent of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry. GO:0048744 negative regulation of skeletal muscle fiber development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048744 negative regulation of skeletal muscle fibre development|down-regulation of skeletal muscle fiber development|inhibition of skeletal muscle fiber development|negative regulation of skeletal myofibre development|down regulation of skeletal muscle fiber development|negative regulation of skeletal myofiber development|downregulation of skeletal muscle fiber development Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast. CHEBI:23436 cyanogenic glycoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23436 CHEBI:23437 cyanohydrin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_23437 GO:1902815 N,N'-diacetylchitobiose import biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902815 The directed movement of N,N'-diacetylchitobiose into a cell or organelle. GO:0048745 smooth muscle tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048745 The process whose specific outcome is the progression of smooth muscle over time, from its formation to the mature structure. GO:1902812 regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902812 regulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|regulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination Any process that modulates the frequency, rate or extent of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry. GO:0048746 obsolete smooth muscle fiber development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048746 smooth muscle fibre development|smooth muscle fiber development OBSOLETE. The process whose specific outcome is the progression of smooth muscle fiber over time, from its formation to the mature structure. GO:0048747 muscle fiber development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048747 myofibre development|myofiber development|muscle fibre development The process whose specific outcome is the progression of the muscle fiber over time, from its formation to the mature structure. In skeletal muscle, fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast. GO:1902813 negative regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902813 inhibition of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|down-regulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|negative regulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|down-regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry|inhibition of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|downregulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry|down regulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|downregulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|down regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry|inhibition of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry|down regulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|negative regulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|downregulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|down-regulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry Any process that stops, prevents or reduces the frequency, rate or extent of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry. GO:1902810 negative regulation of skeletal muscle fiber differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902810 inhibition of skeletal muscle fiber differentiation|down regulation of skeletal muscle fiber differentiation|downregulation of skeletal muscle fiber differentiation|down-regulation of skeletal muscle fiber differentiation Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle fiber differentiation. GO:1902811 positive regulation of skeletal muscle fiber differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902811 up-regulation of skeletal muscle fiber differentiation|upregulation of skeletal muscle fiber differentiation|up regulation of skeletal muscle fiber differentiation|activation of skeletal muscle fiber differentiation Any process that activates or increases the frequency, rate or extent of skeletal muscle fiber differentiation. UBERON:0000060 anatomical wall biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000060 wall|wall of organ|organ wall Organ component adjacent to an organ cavity and which consists of a maximal aggregate of organ component layers. UBERON:0000061 anatomical structure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000061 connected biological structure|biological structure Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome. UBERON:0000062 organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000062 body organ|anatomical unit|element Anatomical structure that performs a specific function or group of functions [WP]. UBERON:0000063 organ subunit biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000063 segment of organ|organ region with fixed fiat boundary|organ segment A part of an organ that constitutes a distinct modular sub-unit. In some cases, the organ may also contain other sub-units of identical or similar types, in other cases this may be a distinct entity. GO:0048748 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048748 UBERON:0000068 embryo stage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000068 embryonic stage|embryogenesis A life cycle stage that starts with fertilization and ends with the fully formed embryo. UBERON:0000069 larval stage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000069 trochophore stage|zoea stage|naiad, nymph|caterpillar|naiad, nymph stage|wriggler|caterpillar stage|bipinnaria|nauplius|wriggler stage|veliger|metacestode|nauplius stage|bipinnaria stage|veliger stage|larva stage|planula|tornaria|planula stage|larva|ammocoete|ammocoete stage|nymph|maggot|nymph stage|grub|maggot stage|glochidium|grub stage|glochidium stage|leptocephalus|leptocephalus stage|zoea|trochophore A distinct juvenile stage many animals undergo before metamorphosis into adults. Animals with indirect development such as insects, amphibians, or cnidarians typically have a larval phase of their life cycle. GO:0048749 compound eye development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048749 insect-type retina development The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye. UBERON:0000064 organ part biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000064 regional part of organ|cardinal organ part A multicellular structure that is a part of an organ. UBERON:0000065 respiratory tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000065 Anatomical structure that is part of the respiratory system. In mammals consists of upper and lower tracts UBERON:0000066 fully formed stage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000066 adult stage|fully formed animal stage|juvenile-adult stage The stage of development at which the animal is fully formed, including immaturity and maturity. Includes both sexually immature stage, and adult stage. CHEBI:23443 cyclic amide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23443 GO:1902829 regulation of spinal cord association neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902829 regulation of spinal cord dorsal interneuron differentiation Any process that modulates the frequency, rate or extent of spinal cord association neuron differentiation. GO:0048751 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048751 GO:0048752 semicircular canal morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048752 embryonic semicircular canal morphogenesis The process in which the anatomical structures of the semicircular canals are generated and organized. GO:1902827 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902827 GO:0048753 pigment granule organization biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0048753 pigment granule organization and biogenesis|pigment granule organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pigment granule. GO:1902828 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902828 GO:0048754 branching morphogenesis of an epithelial tube biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048754 tubulogenesis The process in which the anatomical structures of branches in an epithelial tube are generated and organized. A tube is a long hollow cylinder. GO:1902825 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902825 GO:0048755 branching morphogenesis of a nerve biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048755 The process in which the anatomical structures of branches in a nerve are generated and organized. This term refers to an anatomical structure (nerve) not a cell (neuron). CHEBI:23447 cyclic nucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23447 GO:1902826 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902826 GO:0048756 sieve cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048756 The process in which a relatively unspecialized cell acquires specialized features of a sieve cell. A sieve cell is a type of sieve element that has relatively undifferentiated sieve areas (with narrow pores). The sieve areas are rather uniform in structure on all walls; that is, there are no sieve plates. Typical of gymnosperms and lower vascular plants. The sieve element is the cell in the phloem tissue concerned with mainly longitudinal conduction of food materials. CHEBI:23448 cyclic oligosaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23448 GO:1902823 negative regulation of late endosome to lysosome transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902823 down-regulation of late endosome to lysosome transport|inhibition of late endosome to lysosome transport|down regulation of late endosome to lysosome transport|downregulation of late endosome to lysosome transport Any process that stops, prevents or reduces the frequency, rate or extent of late endosome to lysosome transport. GO:0048757 pigment granule maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048757 Steps required to form a membrane-bounded organelle into a pigment granule containing pigment. Maturation is a developmental process, independent of morphogenetic (shape) change, that is required for a cell or structure to attain its fully functional state. CHEBI:23445 cyclic hydroxamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23445 GO:0048758 companion cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048758 The process in which a relatively unspecialized cell acquires specialized features of a companion cell. The companion cell is the specialized parenchyma cell associated with a sieve-tube member in angiosperm phloem and arising from the same mother cell as the sieve-tube member. GO:1902824 positive regulation of late endosome to lysosome transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902824 up regulation of late endosome to lysosome transport|activation of late endosome to lysosome transport|up-regulation of late endosome to lysosome transport|upregulation of late endosome to lysosome transport Any process that activates or increases the frequency, rate or extent of late endosome to lysosome transport. CHEBI:23446 cyclic monoterpene ketone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23446 GO:1902821 1-undecene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902821 1-undecene anabolism|1-undecene synthesis|1-undecene formation|1-undecene biosynthesis The chemical reactions and pathways resulting in the formation of 1-undecene. GO:1902822 regulation of late endosome to lysosome transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902822 regulation of prevacuolar compartment to lysosome transport Any process that modulates the frequency, rate or extent of late endosome to lysosome transport. UBERON:0014699 extraembryonic venous system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014699 A venous system that overlaps a umbilical cord and is part of a entire extraembryonic component. GO:1902820 1-undecene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902820 1-undecene metabolism The chemical reactions and pathways involving 1-undecene. UBERON:0014695 deep auricular artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014695 The deep auricular artery often arises in common with the anterior tympanic artery. It ascends in the substance of the parotid gland, behind the temporomandibular articulation, pierces the cartilaginous or bony wall of the external acoustic meatus, and supplies its cuticular lining and the outer surface of the tympanic membrane. It gives a branch to the temporomandibular joint. GO:0048750 compound eye corneal lens morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048750 The process in which the anatomical structures of the compound eye corneal lens are generated and organized. OBO:GOCHE_26013 substance with pheromone role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_26013 GO:0048759 xylem vessel member cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048759 vessel member cell differentiation|vessel element cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a vessel member cell. A vessel member cell is one of the components of a vessel in the xylem. It is a dead cell with the wall between adjacent members being variously perforated and the walls that persist variously thickened. UBERON:0000057 urethra biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000057 the fibromuscular tubular canal through which urine is discharged from the bladder to the exterior via the external urinary meatus; in males, the urethra is joined by the ejaculatory ducts and serves as a passageway for semen during ejaculation, as well as a canal for urine during voiding; in females, the urethra is shorter and emerges above the vaginal opening UBERON:0000058 duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000058 exocrine gland duct|anatomical duct|exocrine duct|ducts A tubular structure that transports secreted or excreted substances. UBERON:0000059 large intestine biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000059 intestinum crassum A subdivision of the digestive tract that connects the small intestine to the cloaca or anus. Lacks or has few villi[Kardong]. CHEBI:23449 cyclic peptide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23449 UBERON:0024045 white matter of the cerebellar cortex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0024045 white matter of the cerebellar cortex White matter that lies deep to the granular cell layer of the cerebellar cortex. It contains afferents to the cerebellar cortex and axons that run between the cerebellar cortex and the deep cerebellar nuclei. UBERON:0000055 vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000055 A tubular structure that contains, conveys body fluid, such as blood or lymph. UBERON:0000056 ureter biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000056 metanephric duct Muscular duct that propels urine from the kidneys to the urinary bladder, or related organs. GO:0048762 mesenchymal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048762 The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types. CHEBI:23410 cumate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23410 GO:0048763 calcium-induced calcium release activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048763 Enables transmembrane transfer of calcium ions from an intracellular store to the cytosol on induction by increased calcium concentration. GO:1902838 regulation of nuclear migration along microtubule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902838 regulation of nucleus migration|regulation of nuclear migration, microtubule-mediated|regulation of transport of nucleus by microtubules|regulation of microtubule cytoskeleton-dependent nucleus positioning|regulation of microtubule-dependent nucleus positioning|regulation of transport of nucleus, microtubule-mediated|regulation of microtubule-mediated nuclear migration|regulation of microtubule cytoskeleton-dependent nuclear positioning|regulation of nuclear movement, microtubule-mediated|regulation of microtubule-dependent nuclear positioning Any process that modulates the frequency, rate or extent of nuclear migration along microtubule. GO:0048764 trichoblast maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048764 A developmental process, independent of morphogenetic (shape) change, that is required for a trichoblast cell to attain its fully functional state. GO:0048765 root hair cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048765 The process in which a relatively unspecialized cell acquires specialized features of a root hair cell. GO:1902839 negative regulation of nuclear migration along microtubule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902839 down-regulation of microtubule-dependent nuclear positioning|negative regulation of microtubule-dependent nuclear positioning|down-regulation of nuclear migration along microtubule|down regulation of nuclear migration, microtubule-mediated|downregulation of transport of nucleus by microtubules|downregulation of microtubule cytoskeleton-dependent nucleus positioning|negative regulation of transport of nucleus, microtubule-mediated|downregulation of nuclear migration, microtubule-mediated|inhibition of microtubule-dependent nuclear positioning|down-regulation of transport of nucleus, microtubule-mediated|inhibition of nuclear migration along microtubule|down regulation of microtubule-dependent nucleus positioning|down regulation of transport of nucleus by microtubules|negative regulation of microtubule-mediated nuclear migration|down-regulation of microtubule-mediated nuclear migration|negative regulation of microtubule cytoskeleton-dependent nuclear positioning|down regulation of microtubule cytoskeleton-dependent nucleus positioning|inhibition of transport of nucleus by microtubules|down-regulation of microtubule cytoskeleton-dependent nuclear positioning|inhibition of microtubule cytoskeleton-dependent nucleus positioning|downregulation of microtubule-dependent nucleus positioning|negative regulation of nuclear migration, microtubule-mediated|downregulation of transport of nucleus, microtubule-mediated|down-regulation of nuclear migration, microtubule-mediated|downregulation of microtubule-mediated nuclear migration|downregulation of microtubule cytoskeleton-dependent nuclear positioning|down regulation of microtubule-dependent nuclear positioning|down-regulation of microtubule-dependent nucleus positioning|down regulation of nuclear migration along microtubule|negative regulation of microtubule-dependent nucleus positioning|down regulation of transport of nucleus, microtubule-mediated|inhibition of transport of nucleus, microtubule-mediated|down regulation of microtubule-mediated nuclear migration|inhibition of microtubule-mediated nuclear migration|inhibition of nuclear migration, microtubule-mediated|down regulation of microtubule cytoskeleton-dependent nuclear positioning|inhibition of microtubule cytoskeleton-dependent nuclear positioning|downregulation of nuclear migration along microtubule|downregulation of microtubule-dependent nuclear positioning|inhibition of microtubule-dependent nucleus positioning|down-regulation of transport of nucleus by microtubules|negative regulation of transport of nucleus by microtubules|negative regulation of microtubule cytoskeleton-dependent nucleus positioning|down-regulation of microtubule cytoskeleton-dependent nucleus positioning Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration along microtubule. UBERON:0000039 follicular antrum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000039 ovarian follicle antrum|antral cavity|antrum folliculare|antrum follicularum Region of ovarian follicle filled with follicular fluid. GO:1902836 positive regulation of proline import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902836 up regulation of proline import into cell|upregulation of proline import into cell|positive regulation of proline import into cell|up-regulation of proline import into cell|activation of proline import into cell Any process that activates or increases the frequency, rate or extent of proline import into cell. GO:0048766 root hair initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048766 The process in which a protrusion or bulge is formed at the site of plant root hair outgrowth. GO:0048767 root hair elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048767 The process in which the root hair grows longer. GO:1902837 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902837 GO:1902834 regulation of proline import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902834 regulation of proline import into cell Any process that modulates the frequency, rate or extent of proline import into cell. CHEBI:23412 cumic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23412 GO:0048768 root hair cell tip growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048768 root hair tip growth Localized growth of a plant root hair tip by extension of the cell wall. GO:1902835 negative regulation of proline import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902835 down-regulation of proline import into cell|downregulation of proline import into cell|down regulation of proline import into cell|inhibition of proline import into cell|negative regulation of proline import into cell Any process that stops, prevents or reduces the frequency, rate or extent of proline import into cell. GO:0048769 sarcomerogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048769 myofibril production The process in which sarcomeres are added in series within a fiber. GO:1902832 negative regulation of cell proliferation in dorsal spinal cord biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902832 down regulation of cell proliferation in dorsal spinal cord|inhibition of cell proliferation in dorsal spinal cord|down-regulation of cell proliferation in dorsal spinal cord|downregulation of cell proliferation in dorsal spinal cord Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in dorsal spinal cord. UBERON:0014687 temporal sulcus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014687 temporal lobe sulci|temporal lobe sulcus Any of three grooves in the temporal lobe including the inferior, middle, and superior temporal sulci. GO:1902833 positive regulation of cell proliferation in dorsal spinal cord biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902833 upregulation of cell proliferation in dorsal spinal cord|up-regulation of cell proliferation in dorsal spinal cord|activation of cell proliferation in dorsal spinal cord|up regulation of cell proliferation in dorsal spinal cord Any process that activates or increases the frequency, rate or extent of cell proliferation in dorsal spinal cord. GO:1902830 negative regulation of spinal cord association neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902830 down-regulation of spinal cord association neuron differentiation|downregulation of spinal cord association neuron differentiation|down-regulation of spinal cord dorsal interneuron differentiation|negative regulation of spinal cord dorsal interneuron differentiation|down regulation of spinal cord association neuron differentiation|inhibition of spinal cord association neuron differentiation|downregulation of spinal cord dorsal interneuron differentiation|down regulation of spinal cord dorsal interneuron differentiation|inhibition of spinal cord dorsal interneuron differentiation Any process that stops, prevents or reduces the frequency, rate or extent of spinal cord association neuron differentiation. GO:1902831 positive regulation of spinal cord association neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902831 up-regulation of spinal cord dorsal interneuron differentiation|activation of spinal cord dorsal interneuron differentiation|up regulation of spinal cord association neuron differentiation|positive regulation of spinal cord dorsal interneuron differentiation|upregulation of spinal cord association neuron differentiation|up regulation of spinal cord dorsal interneuron differentiation|up-regulation of spinal cord association neuron differentiation|activation of spinal cord association neuron differentiation|upregulation of spinal cord dorsal interneuron differentiation Any process that activates or increases the frequency, rate or extent of spinal cord association neuron differentiation. GO:0048760 plant parenchymal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048760 parenchymal cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a parenchymal cell. Parenchymal cells are the most abundant and versatile cells in plants. They have very few distinguishing characteristics and botanists classify them as any cell type that cannot be assigned to any other structural or functional class. They can redifferentiate and dedifferentiate and are involved in storage, basic metabolism and other processes. The cells are polyhedral, typically with thin, non-lignified cellulose cell walls and nucleate living protoplasm. They vary in size, form, and wall structure. UBERON:0014686 angular vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014686 The angular vein formed by the junction of the frontal vein and supraorbital vein, runs obliquely downward, on the side of the root of the nose, to the level of the lower margin of the orbit, where it becomes the anterior facial vein. It receives the external nasal veins of the ala nasi, and communicates with the superior ophthalmic vein through the nasofrontal vein, thus establishing an important anastomosis between the anterior facial vein and the cavernous sinus. GO:0048761 collenchyma cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048761 The process in which a relatively unspecialized cell acquires specialized features of a collenchyma cell. This is a plant cell in which the primary cell walls are unevenly thickened, with most thickening occurring at the cell corners. Cells are living and able to grow, they are elongated, and lignin and secondary walls absent. Collenchyma cells make up collenchyma tissue which acts as a supporting tissue in growing shoots, leaves and petioles. This tissue is often arranged in cortical ribs, as seen prominently in celery and rhubarb petioles. UBERON:0000047 simple eye biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000047 An eye with one concave chamber. Note that 'simple' does not imply a reduced level of complexity or acuity. CHEBI:23417 cutins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23417 UBERON:0000042 serous membrane biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000042 wall of serous sac|tunica serosa|serosa multi-tissue structure that is comprised of a secretory epithelial layer (mesothelium) and a connective tissue layer. UBERON:0000043 tendon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000043 sinew|tendo Dense regular connective tissue that connects muscle to bone[VSAO]. UBERON:0000044 dorsal root ganglion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000044 DRG|ganglion of dorsal root|ganglion sensorium nervi spinalis|ganglion spinalis|posterior root ganglion|spinal ganglion part of peripheral nervous system|dorsal root ganglion|ganglion spinale|spinal ganglion|dorsal root ganglia Sensory ganglia located on the dorsal spinal roots within the vertebral column. The spinal ganglion cells are pseudounipolar. The single primary branch bifurcates sending a peripheral process to carry sensory information from the periphery and a central branch which relays that information to the spinal cord or brain. (MSH) * ganglion found on the posterior root of each spinal nerve, composed of the unipolar nerve cell bodies of the sensory neurons of the nerve. (CSP) UBERON:0000045 ganglion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000045 ganglia|neural ganglion A biological tissue mass, most commonly a mass of nerve cell bodies. GO:0048773 erythrophore differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048773 erythrophore cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of an erythrophore cell. Erythrophores are pigment cells derived from the neural crest. They contain pteridine and/or carotenoid pigments in structures called pterinosomes or erythrosomes. This gives them an orange to red appearance. GO:0048774 cyanophore differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048774 cyanophore cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a cyanophore cell. Cyanophores are pigment cells derived from the neural crest. They contain a blue pigment of unknown chemical composition. The pigment is stored in fibrous organelles termed cyanosomes. GO:1902849 positive regulation of neuronal signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902849 up regulation of neuronal signal transduction|upregulation of neuronal signal transduction|up-regulation of neuronal signal transduction|activation of neuronal signal transduction Any process that activates or increases the frequency, rate or extent of neuronal signal transduction. GO:0048775 regulation of leucophore differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048775 Any process that modulates the frequency, rate or extent of leucophore differentiation. GO:0048776 negative regulation of leucophore differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048776 down-regulation of leucophore differentiation|downregulation of leucophore differentiation|down regulation of leucophore differentiation|inhibition of leucophore differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of leucophore differentiation. GO:1902847 regulation of neuronal signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902847 Any process that modulates the frequency, rate or extent of neuronal signal transduction. GO:0048777 positive regulation of leucophore differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048777 stimulation of leucophore differentiation|up-regulation of leucophore differentiation|activation of leucophore differentiation|up regulation of leucophore differentiation|upregulation of leucophore differentiation Any process that activates or increases the frequency, rate or extent of leucophore differentiation. GO:1902848 negative regulation of neuronal signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902848 down-regulation of neuronal signal transduction|downregulation of neuronal signal transduction|down regulation of neuronal signal transduction|inhibition of neuronal signal transduction Any process that stops, prevents or reduces the frequency, rate or extent of neuronal signal transduction. GO:0048778 regulation of erythrophore differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048778 Any process that modulates the frequency, rate or extent of erythrophore differentiation. UBERON:0000029 lymph node biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000029 lymph gland|nodus lymphaticus Any of the rounded masses of lymphoid tissue that are surrounded by a capsule of connective tissue, are distributed along the lymphatic vessels, and contain numerous lymphocytes which filter the flow of lymph. GO:1902845 negative regulation of mitotic spindle elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902845 down regulation of mitotic spindle elongation|inhibition of mitotic spindle elongation|down-regulation of spindle elongation during mitosis|negative regulation of spindle elongation during mitosis|inhibition of spindle elongation during mitosis|down-regulation of mitotic spindle elongation|down regulation of spindle elongation during mitosis|downregulation of spindle elongation during mitosis|downregulation of mitotic spindle elongation Any process that stops, prevents or reduces the frequency, rate or extent of mitotic spindle elongation. GO:0048779 negative regulation of erythrophore differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048779 down-regulation of erythrophore differentiation|downregulation of erythrophore differentiation|down regulation of erythrophore differentiation|inhibition of erythrophore differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of erythrophore differentiation. CHEBI:23423 pseudohalogen oxoacid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23423 GO:1902846 positive regulation of mitotic spindle elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902846 activation of spindle elongation during mitosis|positive regulation of spindle elongation during mitosis|upregulation of mitotic spindle elongation|up-regulation of spindle elongation during mitosis|activation of mitotic spindle elongation|up-regulation of mitotic spindle elongation|upregulation of spindle elongation during mitosis|up regulation of mitotic spindle elongation|up regulation of spindle elongation during mitosis Any process that activates or increases the frequency, rate or extent of mitotic spindle elongation. CHEBI:23424 cyanides biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23424 GO:1902843 positive regulation of netrin-activated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902843 up regulation of netrin-activated signalling pathway|activation of netrin-activated signalling pathway|positive regulation of netrin-activated signalling pathway|upregulation of netrin-activated signaling pathway|up regulation of netrin-mediated signaling pathway|upregulation of netrin signaling pathway|activation of netrin-mediated signaling pathway|upregulation of netrin-activated signal transduction pathway|positive regulation of netrin-mediated signaling pathway|up-regulation of netrin-activated signaling pathway|activation of netrin-activated signaling pathway|up-regulation of netrin-activated signalling pathway|up-regulation of netrin-activated signal transduction pathway|up-regulation of netrin signaling pathway|activation of netrin-activated signal transduction pathway|activation of netrin signaling pathway|up-regulation of netrin-mediated signaling pathway|upregulation of netrin-activated signalling pathway|up regulation of netrin-activated signaling pathway|positive regulation of netrin-activated signal transduction pathway|positive regulation of netrin signaling pathway|upregulation of netrin-mediated signaling pathway|up regulation of netrin-activated signal transduction pathway|up regulation of netrin signaling pathway Any process that activates or increases the frequency, rate or extent of netrin-activated signaling pathway. GO:1902844 positive regulation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902844 upregulation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway|positive regulation of spinal cord dorsal interneuron differentiation by negative regulation of canonical Wnt signaling pathway|up regulation of spinal cord dorsal interneuron differentiation by negative regulation of canonical Wnt signaling pathway|activation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway|up-regulation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway|upregulation of spinal cord dorsal interneuron differentiation by negative regulation of canonical Wnt signaling pathway|activation of spinal cord dorsal interneuron differentiation by negative regulation of canonical Wnt signaling pathway|up-regulation of spinal cord dorsal interneuron differentiation by negative regulation of canonical Wnt signaling pathway|up regulation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway A negative regulation of canonical Wnt signaling pathway that results in positive regulation of spinal cord association neuron differentiation. GO:1902841 regulation of netrin-activated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902841 regulation of netrin-activated signal transduction pathway|regulation of netrin signaling pathway|regulation of netrin-activated signalling pathway|regulation of netrin-mediated signaling pathway Any process that modulates the frequency, rate or extent of netrin-activated signaling pathway. GO:1902842 negative regulation of netrin-activated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902842 downregulation of netrin signaling pathway|down regulation of netrin-activated signaling pathway|downregulation of netrin-activated signal transduction pathway|inhibition of netrin-activated signaling pathway|downregulation of netrin-mediated signaling pathway|down regulation of netrin signaling pathway|down regulation of netrin-activated signal transduction pathway|inhibition of netrin signaling pathway|inhibition of netrin-activated signal transduction pathway|down-regulation of netrin-activated signalling pathway|negative regulation of netrin-activated signalling pathway|negative regulation of netrin-mediated signaling pathway|down-regulation of netrin-mediated signaling pathway|inhibition of netrin-activated signalling pathway|inhibition of netrin-mediated signaling pathway|down-regulation of netrin-activated signaling pathway|down-regulation of netrin signaling pathway|down-regulation of netrin-activated signal transduction pathway|negative regulation of netrin-activated signal transduction pathway|negative regulation of netrin signaling pathway|down regulation of netrin-activated signalling pathway|downregulation of netrin-activated signaling pathway|down regulation of netrin-mediated signaling pathway|downregulation of netrin-activated signalling pathway Any process that stops, prevents or reduces the frequency, rate or extent of netrin-activated signaling pathway. GO:1902840 positive regulation of nuclear migration along microtubule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902840 activation of transport of nucleus by microtubules|up-regulation of transport of nucleus by microtubules|up-regulation of microtubule cytoskeleton-dependent nucleus positioning|activation of microtubule cytoskeleton-dependent nucleus positioning|up-regulation of nuclear migration, microtubule-mediated|upregulation of transport of nucleus, microtubule-mediated|upregulation of microtubule-mediated nuclear migration|upregulation of microtubule cytoskeleton-dependent nuclear positioning|up regulation of microtubule-dependent nuclear positioning|up-regulation of microtubule-dependent nucleus positioning|up regulation of nuclear migration along microtubule|activation of microtubule-dependent nuclear positioning|activation of nuclear migration along microtubule|positive regulation of microtubule-dependent nuclear positioning|positive regulation of transport of nucleus by microtubules|positive regulation of microtubule cytoskeleton-dependent nucleus positioning|upregulation of nuclear migration, microtubule-mediated|up-regulation of transport of nucleus, microtubule-mediated|activation of transport of nucleus, microtubule-mediated|up-regulation of microtubule-mediated nuclear migration|up regulation of transport of nucleus by microtubules|activation of microtubule-mediated nuclear migration|up regulation of microtubule cytoskeleton-dependent nucleus positioning|up-regulation of microtubule cytoskeleton-dependent nuclear positioning|activation of microtubule cytoskeleton-dependent nuclear positioning|upregulation of microtubule-dependent nucleus positioning|up-regulation of nuclear migration along microtubule|up-regulation of microtubule-dependent nuclear positioning|up regulation of nuclear migration, microtubule-mediated|positive regulation of transport of nucleus, microtubule-mediated|upregulation of transport of nucleus by microtubules|activation of nuclear migration, microtubule-mediated|upregulation of microtubule cytoskeleton-dependent nucleus positioning|positive regulation of microtubule-mediated nuclear migration|positive regulation of nuclear migration, microtubule-mediated|positive regulation of microtubule cytoskeleton-dependent nuclear positioning|up regulation of transport of nucleus, microtubule-mediated|up regulation of microtubule-dependent nucleus positioning|up regulation of microtubule-mediated nuclear migration|up regulation of microtubule cytoskeleton-dependent nuclear positioning|activation of microtubule-dependent nucleus positioning|positive regulation of microtubule-dependent nucleus positioning|upregulation of microtubule-dependent nuclear positioning|upregulation of nuclear migration along microtubule Any process that activates or increases the frequency, rate or extent of nuclear migration along microtubule. GO:0048770 pigment granule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0048770 A small, subcellular membrane-bounded vesicle containing pigment and/or pigment precursor molecules. Pigment granule biogenesis is poorly understood, as pigment granules are derived from multiple sources including the endoplasmic reticulum, coated vesicles, lysosomes, and endosomes. GO:0048771 tissue remodeling biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0048771 The reorganization or renovation of existing tissues. This process can either change the characteristics of a tissue such as in blood vessel remodeling, or result in the dynamic equilibrium of a tissue such as in bone remodeling. GO:0048772 leucophore differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048772 leucophore cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a leucophore cell. Leucophores are pigment cells derived from the neural crest. They contain uric acid or other purine crystals, deposited in stacks called leucosomes. This gives them a white appearance. UBERON:0000030 lamina propria biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000030 tunica propria|lamina propria mucosa|lamina propria mucosae A thin layer of loose connective tissue which lies beneath the epithelium and together with the epithelium constitutes the mucosa[WP]. The lamina propria contains capillaries and a central lacteal (lymph vessel) in the small intestine, as well as lymphoid tissue. Lamina propria also contains glands with the ducts opening on to the mucosal epithelium, that secrete mucus and serous secretions. UBERON:0000035 primary ovarian follicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000035 folliculus ovaricus primarius|primary follicle of ovary|primary ovarian follicle|ovary primary follicle|primary follicle|preantral follicle of ovary|primary egg follicle An ovarian follicle that has one layer of granulosa cells. UBERON:0000036 secondary ovarian follicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000036 ovary secondary follicle|preantral follicle|secondary follicle|secondary egg follicle|pre-antral follicle|pre-ovulatory follicle|folliculus ovaricus secondarius|secondary follicle of ovary|antral follicle of ovary A maturing ovarian follicle that has two more more layers of granulosa cells, up to the onset of antrum formation. UBERON:0000037 tertiary ovarian follicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000037 folliculi ovarici vesiculosi|folliculus ovaricus tertiarius|antral ovarian follicle|ovary antral follicle|vesicular follicle of ovary|folliculus ovaricus tertiarius (vesiculosus)|folliculus ovaricus tertiarius (vesiculous)|Graafian follicle|tertiary egg follicle|antral follicle|vesicular ovarian follicle|tertiary follicle of ovary A follicle that has reached the most mature stage of folliculogenesis, characterized by the presence of the antrum UBERON:0000038 follicular fluid biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000038 ovary follicle fluid|liquor folliculi|ovarian follicular fluid|liquor follicularis|ovary follicular fluid|liquor folliculi|antral fluid, ovarian follicle The fluid surrounding the ovum and granulosa cells in the ovarian follicle. UBERON:0000031 lamina propria of trachea biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000031 trachea lamina propria|lamina propria mucosa of trachea|tracheal lamina propria|trachea lamina propria mucosa|windpipe lamina propria mucosae|lamina propria mucosa of windpipe|windpipe lamina propria|lamina propria mucosae of trachea|windpipe lamina propria mucosa|lamina propria mucosae of windpipe|trachea lamina propria mucosae|lamina propria of windpipe A lamina propria that is part of a respiratory airway. UBERON:0000033 head biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000033 head (volume)|adult head|cephalic area The head is the anterior-most division of the body [GO]. GO:0048784 pigment biosynthetic process involved in pigment granule maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048784 pigment biosynthetic process during pigment granule maturation The chemical reactions and pathways resulting in the formation of a pigment, contributing to the process in which a membrane-bounded organelle develops into a pigment granule. Maturation is a developmental process, independent of morphogenetic (shape) change, that is required for a cell or structure to attain its fully functional state. GO:0048785 hatching gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048785 The process whose specific outcome is the progression of the hatching gland over time, from its formation to the mature structure. The cells of the hatching gland contain enzymes responsible for solubilization of the egg chorion, facilitating the hatching process. GO:0048786 presynaptic active zone biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0048786 NIF_Subcellular:sao792027222 pre-synaptic active zone component|presynaptic specialization|pre-synaptic active zone A specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, and a specialized cortical cytoskeletal matrix. GO:0048787 presynaptic active zone membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0048787 NIF_Subcellular:sao2038461087 active zone presynaptic plasma membrane|active zone pre-synaptic plasma membrane|pre-synaptic active zone membrane|active zone plasma membrane The membrane portion of the presynaptic active zone; it is the site where docking and fusion of synaptic vesicles occurs for the release of neurotransmitters. GO:0048788 cytoskeleton of presynaptic active zone biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0048788 NIF_Subcellular:sao1470121605 CAZ|synaptic ribbon|presynaptic cytoskeletal matrix assembled at active zones|T-bar ribbon|ribbon|pre-synaptic dense body|T-bar|presynaptic ribbon|active zone cytomatrix|pre-synaptic ribbon|presynaptic dense body|presynaptic cytomatrix assembled at active zones|presynaptic cytoskeletal matrix|pre-synaptic cytoskeletal matrix assembled at active zones The specialized cytoskeletal matrix of the presynaptic active zone. It has specialized functions in organizing synaptic events such as immobilisation or translocation of synaptic vesicles, and assembling active zone components. It is believed to form a molecular scaffold that organizes neurotransmitter release sites. GO:1902858 propionyl-CoA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902858 propionyl-CoA metabolism The chemical reactions and pathways involving propionyl-CoA. GO:1902859 propionyl-CoA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902859 propionyl-CoA breakdown|propionyl-CoA catabolism|propionyl-CoA degradation The chemical reactions and pathways resulting in the breakdown of propionyl-CoA. GO:0048789 cytoskeletal matrix organization at active zone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048789 cytoskeletal matrix organisation at active zone The assembly and arrangement of cytomatrix proteins to form complexes in the cell cortex beneath the active zone, i.e. just beneath the presynaptic plasma membrane. GO:1902856 negative regulation of non-motile cilium assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902856 down-regulation of nonmotile primary cilia assembly|negative regulation of nonmotile primary cilia assembly|negative regulation of sensory cilium biogenesis|down-regulation of sensory cilium biogenesis|negative regulation of immotile primary cilium assembly|down-regulation of immotile primary cilium assembly|downregulation of nonmotile primary cilia assembly|negative regulation of nonmotile primary cilium assembly|down regulation of nonmotile primary cilia assembly|inhibition of sensory cilium biogenesis|down regulation of nonmotile primary cilium assembly|down regulation of sensory cilium assembly|downregulation of immotile primary cilium assembly|downregulation of nonmotile primary cilium assembly|inhibition of immotile primary cilium assembly|downregulation of sensory cilium assembly|down regulation of sensory cilium biogenesis|inhibition of nonmotile primary cilia assembly|down regulation of immotile primary cilium assembly|downregulation of sensory cilium biogenesis|down-regulation of sensory cilium assembly|negative regulation of sensory cilium assembly|down-regulation of nonmotile primary cilium assembly|inhibition of sensory cilium assembly|inhibition of nonmotile primary cilium assembly Any process that stops, prevents or reduces the frequency, rate or extent of non-motile cilium assembly. GO:1902857 positive regulation of non-motile cilium assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902857 activation of nonmotile primary cilia assembly|up-regulation of immotile primary cilium assembly|up-regulation of nonmotile primary cilium assembly|up-regulation of sensory cilium assembly|activation of sensory cilium biogenesis|positive regulation of nonmotile primary cilia assembly|up regulation of nonmotile primary cilia assembly|positive regulation of nonmotile primary cilium assembly|up-regulation of sensory cilium biogenesis|upregulation of nonmotile primary cilium assembly|upregulation of sensory cilium assembly|positive regulation of immotile primary cilium assembly|up regulation of immotile primary cilium assembly|upregulation of nonmotile primary cilia assembly|upregulation of sensory cilium biogenesis|activation of nonmotile primary cilium assembly|activation of sensory cilium assembly|up regulation of sensory cilium assembly|up regulation of nonmotile primary cilium assembly|positive regulation of sensory cilium assembly|upregulation of immotile primary cilium assembly|up-regulation of nonmotile primary cilia assembly|up regulation of sensory cilium biogenesis|positive regulation of sensory cilium biogenesis|activation of immotile primary cilium assembly Any process that activates or increases the frequency, rate or extent of non-motile cilium assembly. GO:1902854 positive regulation of nuclear migration during mitotic telophase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902854 upregulation of nuclear migration during mitotic telophase|activation of nuclear migration during mitotic telophase|up-regulation of nuclear migration during mitotic telophase|up regulation of nuclear migration during mitotic telophase Any process that activates or increases the frequency, rate or extent of nuclear migration during mitotic telophase. GO:1902855 regulation of non-motile cilium assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902855 regulation of nonmotile primary cilium assembly|regulation of nonmotile primary cilia assembly|regulation of sensory cilium assembly|regulation of immotile primary cilium assembly|regulation of sensory cilium biogenesis Any process that modulates the frequency, rate or extent of non-motile cilium assembly. GO:1902852 regulation of nuclear migration during mitotic telophase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902852 Any process that modulates the frequency, rate or extent of nuclear migration during mitotic telophase. GO:1902853 negative regulation of nuclear migration during mitotic telophase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902853 downregulation of nuclear migration during mitotic telophase|down regulation of nuclear migration during mitotic telophase|inhibition of nuclear migration during mitotic telophase|down-regulation of nuclear migration during mitotic telophase Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration during mitotic telophase. GO:1902850 microtubule cytoskeleton organization involved in mitosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902850 microtubule cytoskeleton organisation involved in mitosis|microtubule dynamics involved in mitosis|microtubule cytoskeleton organization and biogenesis involved in mitosis Any microtubule cytoskeleton organization that is involved in mitosis. GO:0048780 positive regulation of erythrophore differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048780 stimulation of erythrophore differentiation|up-regulation of erythrophore differentiation|activation of erythrophore differentiation|up regulation of erythrophore differentiation|upregulation of erythrophore differentiation Any process that activates or increases the frequency, rate or extent of erythrophore differentiation. GO:0048781 regulation of cyanophore differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048781 Any process that modulates the frequency, rate or extent of cyanophore differentiation. GO:0048782 negative regulation of cyanophore differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048782 downregulation of cyanophore differentiation|down regulation of cyanophore differentiation|inhibition of cyanophore differentiation|down-regulation of cyanophore differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of cyanophore differentiation. GO:0048783 positive regulation of cyanophore differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048783 up regulation of cyanophore differentiation|upregulation of cyanophore differentiation|stimulation of cyanophore differentiation|up-regulation of cyanophore differentiation|activation of cyanophore differentiation Any process that activates or increases the frequency, rate or extent of cyanophore differentiation. GO:0097719 neural tissue regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097719 neuroregeneration The regrowth of neural tissue following its loss or destruction. GO:0097717 copper ion transport across blood-cerebrospinal fluid barrier biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097717 copper ion transport across blood/cerebrospinal fluid barrier|copper ion transport across BCB|copper ion transport across blood-CSF barrier|copper ion transport across blood/CSF barrier|copper ion transport across BCSFB The directed movement of copper (Cu) ions passing through the blood-cerebrospinal fluid barrier. GO:0097718 disordered domain specific binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097718 disordered protein domain specific binding Interacting selectively and non-covalently with a disordered domain of a protein. GO:0097715 cellular response to viscosity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097715 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a viscosity stimulus. GO:0097716 copper ion transport across blood-brain barrier biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097716 copper ion transport across BBB The directed movement of copper (Cu) ions passing through the blood-brain barrier. GO:0097713 dolichol-phosphate-mannose synthase regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097713 Binds to and modulates the activity of dolichol-phosphate-mannose synthase. GO:0097714 response to viscosity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097714 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a viscosity stimulus. GO:0097711 ciliary basal body-plasma membrane docking biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097711 Reactome:R-HSA-5620912.1 anchoring of the basal body to the plasma membrane|ciliary basal body docking The docking of a cytosolic centriole/basal body to the plasma membrane via the ciliary transition fibers. In some species this may happen via an intermediate step, by first docking to the ciliary vesicle via the ciliary transition fibers. The basal body-ciliary vesicle then relocates to the plasma membrane, followed by the ciliary vesicle fusing with the plasma membrane, effectively attaching the basal body to the plasma membrane. GO:0097712 vesicle targeting, trans-Golgi to periciliary membrane compartment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097712 The process in which vesicles formed at the trans-Golgi network are directed to the plasma membrane surrounding the base of the cilium, including the ciliary pocket, mediated by molecules at the vesicle membrane and target membrane surfaces. GO:0097710 viral terminase, small subunit biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097710 virus terminase, small subunit The part of the viral terminase complex that acts as a phage DNA-recognition component and regulates the activity of the large subunit. The small subunit usually assembles as a heterooligomer with the large subunit. GO:0048795 swim bladder morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048795 gas bladder morphogenesis The process in which the anatomical structure of the swim bladder is generated and organized. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ. GO:0048796 swim bladder maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048796 gas bladder maturation A developmental process, independent of morphogenetic (shape) change, that is required for a swim bladder to attain its fully functional state. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ. GO:0048797 swim bladder formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048797 gas bladder biosynthesis|gas bladder formation The process that gives rise to the swim bladder. This process pertains to the initial formation of a structure from unspecified parts. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ. GO:0048798 swim bladder inflation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048798 gas bladder inflation The expansion of the swim bladder by trapped gases. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ. GO:1902869 regulation of amacrine cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902869 regulation of amacrine neuron differentiation Any process that modulates the frequency, rate or extent of amacrine cell differentiation. GO:0048799 animal organ maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048799 A developmental process, independent of morphogenetic (shape) change, that is required for an animal organ to attain its fully functional state. An organ is a tissue or set of tissues that work together to perform a specific function or functions. CHEBI:23403 coumarins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23403 GO:1902867 negative regulation of retina development in camera-type eye biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902867 down regulation of retina development in camera-type eye|downregulation of retina development in camera-type eye|down-regulation of retinal development|down-regulation of retina development in camera-style eye|negative regulation of retinal development|negative regulation of retina development in camera-style eye|down-regulation of retina development in camera-type eye|downregulation of retina development in camera-style eye|inhibition of retina development in camera-type eye|inhibition of retinal development|down regulation of retina development in camera-style eye|inhibition of retina development in camera-style eye|down regulation of retinal development|downregulation of retinal development Any process that stops, prevents or reduces the frequency, rate or extent of retina development in camera-type eye. CHEBI:23401 coumaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23401 GO:1902868 positive regulation of retina development in camera-type eye biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902868 up-regulation of retina development in camera-style eye|up regulation of retinal development|activation of retina development in camera-style eye|positive regulation of retinal development|up regulation of retina development in camera-type eye|activation of retina development in camera-type eye|activation of retinal development|positive regulation of retina development in camera-style eye|up-regulation of retinal development|up regulation of retina development in camera-style eye|up-regulation of retina development in camera-type eye|upregulation of retinal development|upregulation of retina development in camera-style eye|upregulation of retina development in camera-type eye Any process that activates or increases the frequency, rate or extent of retina development in camera-type eye. GO:1902865 positive regulation of embryonic camera-type eye development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902865 up regulation of embryonic camera-type eye development|activation of embryonic camera-type eye development|up regulation of embryonic eye development|activation of embryonic eye development|positive regulation of embryonic eye development|up-regulation of embryonic camera-type eye development|up-regulation of embryonic eye development|upregulation of embryonic camera-type eye development|upregulation of embryonic eye development Any process that activates or increases the frequency, rate or extent of embryonic camera-type eye development. GO:1902866 regulation of retina development in camera-type eye biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902866 regulation of retina development in camera-style eye|regulation of retinal development Any process that modulates the frequency, rate or extent of retina development in camera-type eye. GO:1902863 regulation of embryonic camera-type eye development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902863 regulation of embryonic eye development Any process that modulates the frequency, rate or extent of embryonic camera-type eye development. GO:0048790 maintenance of presynaptic active zone structure biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0048790 maintenance of pre-synaptic active zone structure A process which maintains the organization and the arrangement of proteins at the active zone to ensure the fusion and docking of vesicles and the release of neurotransmitters. GO:1902864 negative regulation of embryonic camera-type eye development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902864 down-regulation of embryonic camera-type eye development|down-regulation of embryonic eye development|negative regulation of embryonic eye development|inhibition of embryonic camera-type eye development|inhibition of embryonic eye development|down regulation of embryonic camera-type eye development|down regulation of embryonic eye development|downregulation of embryonic camera-type eye development|downregulation of embryonic eye development Any process that stops, prevents or reduces the frequency, rate or extent of embryonic camera-type eye development. GO:1902861 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902861 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048791 The release of a neurotransmitter into the synaptic cleft by exocytosis of synaptic vesicles, where the release step is dependent on a rise in cytosolic calcium ion levels. GO:1902862 obsolete glycerol catabolic process to glycerone phosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902862 glycerol catabolism to glycerone phosphate|glycerol breakdown to glycerone phosphate|glycerol degradation to glycerone phosphate|glycerol catabolic process to glycerone phosphate OBSOLETE. The chemical reactions and pathways resulting in the breakdown of glycerol to glycerone phosphate. GO:0048792 spontaneous exocytosis of neurotransmitter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048792 spontaneous synaptic vesicle exocytosis The release of a neurotransmitter into the synaptic cleft, where the release step is independent of the presence of calcium ions (Ca2+). The neurotransmitter is contained within a membrane-bounded vesicle, and is released by fusion of the vesicle with the presynaptic plasma membrane of a nerve cell. GO:0048793 pronephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048793 pronephric kidney development The process whose specific outcome is the progression of the pronephros over time, from its formation to the mature structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life. GO:1902860 propionyl-CoA biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902860 propionyl-CoA biosynthesis|propionyl-CoA anabolism|propionyl-CoA synthesis|propionyl-CoA formation The chemical reactions and pathways resulting in the formation of propionyl-CoA. GO:0048794 swim bladder development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048794 gas bladder development The process whose specific outcome is the progression of the swim bladder over time, from its formation to the mature structure. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ. UBERON:0000093 sulcus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000093 A depression or fissure in the surface of an organ. UBERON:0000094 membrane organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000094 membrane of organ|membrane Nonparenchymatous organ that primarily consists of dense connective tissue organized into a sheet which interconnects two or more organs, separates two or more body spaces from one another, or surrounds an organ or body part. Examples: interosseous membrane of forearm, obturator membrane, tympanic membrane, fibrous pericardium, fascia lata, dura mater. [FMA] UBERON:0000095 cardiac neural crest biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000095 complexus cristae neuralis cardiacus|cardiac neural crest complex portion of neural crest that develops from the dorsal neural tube. It overlaps the vagal neural crest and migrates to populate the pharyngeal arches 3, 4 and 6 (producing structures in the head) and to the heart, forming connective tissue that separates the great vessels of the heart. [Wikipedia] GO:0097728 9+0 motile cilium biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097728 motile 9+0 cilium|nodal cilium A motile cilium where the axoneme has a ring of nine outer microtubule doublets but no central microtubules (and is therefore called a 9+0 axoneme). UBERON:0000091 bilaminar disc biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000091 bilaminar disk|embryonic disc|bilaminary germ disc|germinal disk|bilaminary embryonic disc|embryonic shield|germinal disc A flattened, almost circular bilaminar plate of cells formed when the inner cell mass (aka embryoblast) forms two epithelial layers, each of a distinct lineage, separated by an extracellular basement membrane: the external (dorsal) layer is called the epiblast and the internal (ventral) layer is called the hypoblast (aka primitive endoderm); together, they compose the bilaminar embryonic disc. GO:0097729 9+2 motile cilium biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097729 conventional motile cilium|motile 9+2 cilium|sperm flagellum A motile cilium where the axoneme has a ring of nine outer microtubule doublets plus two central microtubules (and is therefore called a 9+2 axoneme). UBERON:0000092 post-embryonic stage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000092 postembryonic stage|postembryonic|post-hatching stage stage succeeding embryo, including mature structure GO:0097726 LEM domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097726 lamina-associated polypeptide, emerin, MAN1 domain binding|LAP2, emerin, MAN1 domain binding Interacting selectively and non-covalently with a LEM domain. The LEM domain (for lamina-associated polypeptide, emerin, MAN1 domain) is present in a group of nuclear proteins that bind chromatin through interaction of the LEM motif with the conserved DNA crosslinking protein, barrier-to-autointegration factor (BAF). GO:0097727 blepharoplast biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097727 An intracellular non-membrane-bounded organelle found in multi-ciliated sperm cells of some primitive land plants, and consisting of many radially arranged ninefold symmetric cylinders. The blepharoplast is involved in de novo formation of multiple centrioles; it enlarges and then disintegrates into many procentrioles, which elongate and ultimately nucleate cilia on the surface of the sperm cell. GO:0097724 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0097724 GO:0097725 histone H3-K79 dimethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097725 histone H3 K79 dimethylation|histone lysine H3 K79 dimethylation The modification of histone H3 by addition of two methyl groups to lysine at position 79 of the histone. GO:0097722 sperm motility biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0097722 sperm movement Any process involved in the controlled movement of a sperm cell. GO:0097723 amoeboid sperm motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097723 ameboid sperm movement|amoeboid sperm movement|ameboid sperm motility Any process involved in the controlled movement of an amoeboid sperm cell. GO:0097720 calcineurin-mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097720 calcineurin signaling|calcineurin-mediated signalling Any intracellular signal transduction in which the signal is passed on within the cell by activation of a transcription factor as a consequence of dephosphorylation by Ca(2+)-activated calcineurin. The process begins with calcium-dependent activation of the phosphatase calcineurin. Calcineurin is a calcium- and calmodulin-dependent serine/threonine protein phosphatase with a conserved function in eukaryotic species from yeast to humans. In yeast and fungi, calcineurin regulates stress signaling and cell cycle, and sporulation and virulence in pathogenic fungi. In metazoans, calcineurin is involved in cell commitment, organogenesis and organ development and immune function of T-lymphocytes. By a conserved mechanism, calcineurin phosphatase activates fungal Crz1 and mammalian NFATc by dephosphorylation and translocation of these transcription factors to the nucleus to regulate gene expression. GO:0097721 ciliary vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097721 primary ciliary vesicle|CV A Golgi-derived vesicle to which the ciliary basal body docks via its transitional fibers. Its membrane is compositionally distinct from Golgi membranes, and will become the ciliary membrane once the ciliary vesicle is fused to the plasma membrane. The ciliary vesicle is thought to be formed by multiple smaller vesicles that attach to the transitional fibers and then fuse to form a larger vesicle. GO:1902878 obsolete regulation of BMP signaling pathway involved in spinal cord association neuron specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902878 regulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|regulation of BMP signalling pathway involved in spinal cord association neuron specification|regulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification OBSOLETE. Any process that modulates the frequency, rate or extent of BMP signaling pathway involved in spinal cord association neuron specification. GO:1902879 obsolete negative regulation of BMP signaling pathway involved in spinal cord association neuron specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902879 inhibition of BMP signalling pathway involved in spinal cord association neuron specification|down-regulation of BMP signaling pathway involved in spinal cord association neuron specification|down regulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|negative regulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|down-regulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|downregulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|down regulation of BMP signalling pathway involved in spinal cord association neuron specification|downregulation of BMP signaling pathway involved in spinal cord association neuron specification|downregulation of BMP signalling pathway involved in spinal cord association neuron specification|down regulation of BMP signaling pathway involved in spinal cord association neuron specification|inhibition of BMP signaling pathway involved in spinal cord association neuron specification|downregulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|down-regulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|negative regulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|down regulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|inhibition of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|negative regulation of BMP signalling pathway involved in spinal cord association neuron specification|down-regulation of BMP signalling pathway involved in spinal cord association neuron specification|inhibition of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of BMP signaling pathway involved in spinal cord association neuron specification. GO:1902876 negative regulation of embryonic pattern specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902876 down regulation of embryonic pattern specification|down-regulation of ventral/lateral system|downregulation of embryonic pattern specification|negative regulation of ventral/lateral system|down-regulation of embryonic pattern specification|downregulation of ventral/lateral system|down regulation of ventral/lateral system|inhibition of embryonic pattern specification|inhibition of ventral/lateral system Any process that stops, prevents or reduces the frequency, rate or extent of embryonic pattern specification. GO:1902877 positive regulation of embryonic pattern specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902877 up-regulation of ventral/lateral system|upregulation of embryonic pattern specification|activation of ventral/lateral system|up regulation of embryonic pattern specification|positive regulation of ventral/lateral system|activation of embryonic pattern specification|up regulation of ventral/lateral system|upregulation of ventral/lateral system|up-regulation of embryonic pattern specification Any process that activates or increases the frequency, rate or extent of embryonic pattern specification. GO:1902874 positive regulation of horizontal cell localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902874 activation of horizontal cell positioning|positive regulation of horizontal cell positioning|positive regulation of horizontal cell localisation|up regulation of horizontal cell localisation|upregulation of retinal horizontal cell positioning|positive regulation of laminar positioning of retinal horizontal cell|up regulation of laminar positioning of retinal horizontal cell|up regulation of horizontal cell localization|up-regulation of horizontal cell positioning|upregulation of horizontal cell localisation|up regulation of retinal horizontal cell positioning|activation of retinal horizontal cell positioning|positive regulation of retinal horizontal cell positioning|upregulation of laminar positioning of retinal horizontal cell|upregulation of horizontal cell localization|upregulation of horizontal cell positioning|up-regulation of horizontal cell localisation|activation of horizontal cell localisation|up-regulation of laminar positioning of retinal horizontal cell|up-regulation of retinal horizontal cell positioning|activation of laminar positioning of retinal horizontal cell|up-regulation of horizontal cell localization|up regulation of horizontal cell positioning|activation of horizontal cell localization Any process that activates or increases the frequency, rate or extent of horizontal cell localization. GO:1902875 regulation of embryonic pattern specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902875 regulation of embryonic pattern formation|regulation of ventral/lateral system|regulation of embryonic pattern biosynthesis Any process that modulates the frequency, rate or extent of embryonic pattern specification. GO:1902872 regulation of horizontal cell localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902872 regulation of horizontal cell localisation|regulation of retinal horizontal cell positioning|regulation of laminar positioning of retinal horizontal cell|regulation of horizontal cell positioning Any process that modulates the frequency, rate or extent of horizontal cell localization. GO:1902873 negative regulation of horizontal cell localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902873 down-regulation of laminar positioning of retinal horizontal cell|negative regulation of laminar positioning of retinal horizontal cell|down-regulation of horizontal cell positioning|down-regulation of horizontal cell localization|negative regulation of horizontal cell positioning|downregulation of horizontal cell localisation|down regulation of retinal horizontal cell positioning|downregulation of laminar positioning of retinal horizontal cell|down regulation of horizontal cell localisation|downregulation of retinal horizontal cell positioning|inhibition of horizontal cell positioning|inhibition of horizontal cell localisation|down regulation of laminar positioning of retinal horizontal cell|downregulation of horizontal cell localization|inhibition of laminar positioning of retinal horizontal cell|down regulation of horizontal cell localization|down-regulation of retinal horizontal cell positioning|negative regulation of retinal horizontal cell positioning|inhibition of horizontal cell localization|down regulation of horizontal cell positioning|inhibition of retinal horizontal cell positioning|downregulation of horizontal cell positioning|negative regulation of horizontal cell localisation|down-regulation of horizontal cell localisation Any process that stops, prevents or reduces the frequency, rate or extent of horizontal cell localization. GO:1902870 negative regulation of amacrine cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902870 down regulation of amacrine cell differentiation|inhibition of amacrine neuron differentiation|downregulation of amacrine cell differentiation|down-regulation of amacrine cell differentiation|down regulation of amacrine neuron differentiation|downregulation of amacrine neuron differentiation|inhibition of amacrine cell differentiation|down-regulation of amacrine neuron differentiation|negative regulation of amacrine neuron differentiation Any process that stops, prevents or reduces the frequency, rate or extent of amacrine cell differentiation. GO:1902871 positive regulation of amacrine cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902871 upregulation of amacrine cell differentiation|up-regulation of amacrine neuron differentiation|up regulation of amacrine cell differentiation|activation of amacrine cell differentiation|upregulation of amacrine neuron differentiation|up-regulation of amacrine cell differentiation|up regulation of amacrine neuron differentiation|activation of amacrine neuron differentiation|positive regulation of amacrine neuron differentiation Any process that activates or increases the frequency, rate or extent of amacrine cell differentiation. GO:0034198 cellular response to amino acid starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034198 general amino acid control response|GAAC response Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of amino acids. GO:0034199 activation of protein kinase A activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034199 protein kinase A activation Any process that initiates the activity of the inactive enzyme protein kinase A. GO:1902880 obsolete positive regulation of BMP signaling pathway involved in spinal cord association neuron specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902880 activation of BMP signalling pathway involved in spinal cord association neuron specification|positive regulation of BMP signalling pathway involved in spinal cord association neuron specification|upregulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|up-regulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|up-regulation of BMP signaling pathway involved in spinal cord association neuron specification|activation of BMP signaling pathway involved in spinal cord association neuron specification|up-regulation of BMP signalling pathway involved in spinal cord association neuron specification|up-regulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|upregulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|activation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|upregulation of BMP signalling pathway involved in spinal cord association neuron specification|up regulation of BMP signaling pathway involved in spinal cord association neuron specification|up regulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|positive regulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|activation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|positive regulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|up regulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|up regulation of BMP signalling pathway involved in spinal cord association neuron specification|upregulation of BMP signaling pathway involved in spinal cord association neuron specification OBSOLETE. Any process that activates or increases the frequency, rate or extent of BMP signaling pathway involved in spinal cord association neuron specification. UBERON:0000083 mesonephric tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000083 tubuli mesonephrici|renal tubules A mesonephric tubule is an epithelial tube that is part of the mesonephros[GO]. Genital ridge that is next to the mesonephros[WP]. UBERON:0000084 ureteric bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000084 gemma ureterica|diverticulum metanephricum|ureteric diverticulum|metanephric bud|metanephric diverticulum|ureteric ampulla|diverticulum An epithelial swelling on the Wolffian duct that elongates to invade the adjacent metanephric mesenchyme[MP] UBERON:0000085 morula biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000085 morula (2-16 cells) A spherical embryonic mass of blastomeres formed before the blastula and resulting from cleavage of the fertilized ovum. UBERON:0000080 mesonephros biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000080 mesonephroi|opisto nephros|corpus Wolffi|amphibian adult kidney|middle kidney|Wolffian body|opistonephros|mesonephric kidney|opisthonephros The second stage of the kidney. It serves as the main excretory organ of aquatic vertebrates and as a temporary embryonic kidney in higher vertebrates. It is composed of the mesonephric duct (also called the Wolffian duct), mesonephric tubules, and associated capillary tufts. A single tubule and its associated capillary tuft is called a mesonephric excretory unit; these units are similar in structure and function to nephrons of the adult kidney. The mesonephros is derived from intermediate mesoderm in the vertebrate embryo. UBERON:0000081 metanephros biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000081 definite kidney|hind kidney|metanephric kidney|metanephron|definitive kidney In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine[GO] GO:0034190 apolipoprotein receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034190 Interacting selectively and non-covalently with an apolipoprotein receptor. GO:0034191 apolipoprotein A-I receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034191 Interacting selectively and non-covalently with an apolipoprotein A-I receptor. GO:0034192 D-galactonate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034192 D-galactonate metabolism The chemical reactions and pathways involving D-galactonate, the anion of D-galactonic acid. GO:0034193 L-galactonate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034193 L-galactonate metabolism The chemical reactions and pathways involving L-galactonate, the anion of L-galactonic acid. UBERON:0000086 zona pellucida biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000086 vitelline envelope|pellucid zone|striated membrane|oolemma|zona radiata|zona striata|zona pellucida - vitelline membrane|vitelline membrane A glycoprotein membrane surrounding the plasma membrane of an oocyte. It is a vital constitutive part of the latter, external but not extraneous to it. The zona pellucida first appears in multilaminar primary oocytes. GO:0034194 D-galactonate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034194 MetaCyc:GALACTCAT-PWY D-galactonate degradation|D-galactonate breakdown|D-galactonate catabolism The chemical reactions and pathways resulting in the breakdown of D-galactonate, the anion of D-galactonic acid. GO:0034195 L-galactonate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034195 MetaCyc:GALACTCAT-PWY L-galactonate degradation|L-galactonate breakdown|L-galactonate catabolism The chemical reactions and pathways resulting in the breakdown of L-galactonate, the anion of L-galactonic acid. UBERON:0000087 inner cell mass biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000087 ICM|early embryoblast|embryoblast|pluriblast|embryoblastus; massa cellularis interna; pluriblastus senior A mass of cells that develop into the body of the embryo and some extraembryonic tissues GO:0034196 acylglycerol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034196 glyceride transport The directed movement of an acylglycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An acylglycerol is any mono-, di- or triester of glycerol with (one or more) fatty acids. UBERON:0000088 trophoblast biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000088 trophoblastus|massa cellularis externa|trophoblast layer|trophoderm the mesectodermal cell layer arising from the trophectoderm that erodes the uterine mucosa and contributes to the formation of the placenta GO:0034197 triglyceride transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034197 triacylglycerol transport The directed movement of triglyceride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Triglycerides are important components of plant oils, animal fats and animal plasma lipoproteins. UBERON:0000089 hypoblast (generic) biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000089 hypoblast|future endoderm and mesoderm|mesendoderm|hypoblastus|endomesoderm . GO:1902889 protein localization to spindle microtubule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902889 protein localisation to spindle microtubule|protein localization in spindle microtubule|protein localisation in spindle microtubule A process in which a protein is transported to, or maintained in, a location within a spindle microtubule. GO:1902887 positive regulation of proteasome-activating ATPase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902887 up-regulation of proteasomal ATPase activity|up-regulation of proteasome channel gating activity|up regulation of proteasome channel opening activity|positive regulation of proteasome channel opening activity|up regulation of proteasome-activating ATPase activity|up-regulation of ATPase involved in positive regulation of proteasomal protein catabolic process|activation of proteasome channel gating activity|activation of proteasome-activating ATPase activity|upregulation of proteasomal ATPase activity|activation of proteasome channel opening activity|positive regulation of proteasome channel gating activity|up regulation of proteasome channel gating activity|upregulation of ATPase involved in positive regulation of proteasomal protein catabolic process|up-regulation of proteasome channel opening activity|up-regulation of proteasome-activating ATPase activity|up regulation of proteasomal ATPase activity|activation of proteasomal ATPase activity|positive regulation of proteasomal ATPase activity|upregulation of proteasome channel opening activity|upregulation of proteasome channel gating activity|up regulation of ATPase involved in positive regulation of proteasomal protein catabolic process|positive regulation of ATPase involved in positive regulation of proteasomal protein catabolic process|activation of ATPase involved in positive regulation of proteasomal protein catabolic process|upregulation of proteasome-activating ATPase activity Any process that activates or increases the frequency, rate or extent of proteasome-activating ATPase activity. GO:1902888 protein localization to astral microtubule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902888 protein localisation to astral microtubule|protein localisation in astral microtubule|protein localization in astral microtubule A process in which a protein is transported to, or maintained in, a location within an astral microtubule. GO:1902885 regulation of proteasome-activating ATPase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902885 regulation of proteasomal ATPase activity|regulation of proteasome channel gating activity|regulation of ATPase involved in positive regulation of proteasomal protein catabolic process|regulation of proteasome channel opening activity Any process that modulates the frequency, rate or extent of proteasome-activating ATPase activity. GO:1902886 negative regulation of proteasome-activating ATPase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902886 down-regulation of ATPase involved in positive regulation of proteasomal protein catabolic process|negative regulation of ATPase involved in positive regulation of proteasomal protein catabolic process|inhibition of proteasomal ATPase activity|downregulation of proteasome channel opening activity|downregulation of proteasome-activating ATPase activity|inhibition of ATPase involved in positive regulation of proteasomal protein catabolic process|negative regulation of proteasome channel opening activity|down-regulation of proteasome channel opening activity|negative regulation of proteasome channel gating activity|down-regulation of proteasome channel gating activity|down-regulation of proteasome-activating ATPase activity|down regulation of proteasomal ATPase activity|downregulation of proteasomal ATPase activity|downregulation of proteasome channel gating activity|down regulation of ATPase involved in positive regulation of proteasomal protein catabolic process|inhibition of proteasome-activating ATPase activity|inhibition of proteasome channel opening activity|down regulation of proteasome channel gating activity|downregulation of ATPase involved in positive regulation of proteasomal protein catabolic process|negative regulation of proteasomal ATPase activity|down-regulation of proteasomal ATPase activity|down regulation of proteasome channel opening activity|inhibition of proteasome channel gating activity|down regulation of proteasome-activating ATPase activity Any process that stops, prevents or reduces the frequency, rate or extent of proteasome-activating ATPase activity. GO:1902883 negative regulation of response to oxidative stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902883 down regulation of response to oxidative stress|inhibition of response to oxidative stress|down-regulation of response to oxidative stress|downregulation of response to oxidative stress Any process that stops, prevents or reduces the frequency, rate or extent of response to oxidative stress. GO:1902884 positive regulation of response to oxidative stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902884 upregulation of response to oxidative stress|up-regulation of response to oxidative stress|activation of response to oxidative stress|up regulation of response to oxidative stress Any process that activates or increases the frequency, rate or extent of response to oxidative stress. GO:1902881 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902881 GO:1902882 regulation of response to oxidative stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902882 Any process that modulates the frequency, rate or extent of response to oxidative stress. GO:1902890 regulation of root hair elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902890 Any process that modulates the frequency, rate or extent of root hair elongation. GO:0034187 obsolete apolipoprotein E binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034187 apolipoprotein E binding OBSOLETE. Interacting selectively and non-covalently with apolipoprotein E. UBERON:0000071 death stage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000071 death End of the life of an organism. GO:0034188 apolipoprotein A-I receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034188 Combining with apolipoprotein A-I and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:1902891 negative regulation of root hair elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902891 down-regulation of root hair elongation|downregulation of root hair elongation|down regulation of root hair elongation|inhibition of root hair elongation Any process that stops, prevents or reduces the frequency, rate or extent of root hair elongation. UBERON:0000072 proximo-distal subdivision of respiratory tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000072 respiratory tract|subdivision of respiratory tract An section of a respiratory tract. GO:0034189 very-low-density lipoprotein particle binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034189 very-low-density lipoprotein binding|VLDL binding Interacting selectively and non-covalently with a very-low-density lipoprotein particle, a triglyceride-rich lipoprotein particle that is typically composed of APOB100, APOE and APOCs and has a density of about 1.006 g/ml and a diameter of between 20-80 nm. UBERON:0000073 regional part of nervous system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000073 part of nervous system Any part or collection of parts of the central or peripheral nervous system. Parts may span both CNS and PNS. UBERON:0000074 renal glomerulus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000074 glomerular capillary tuft|Malpighian glomerulus|glomerulus|Malphigian glomerulus|renal corpuscle|glomerular tuft|renal glomeruli|Malpighian tuft|glomerulus renis A capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney[GO]. GO:0097708 intracellular vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097708 Any vesicle that is part of the intracellular region. GO:0097709 connective tissue replacement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097709 The series of events leading to growth of connective tissue when loss of tissues that are incapable of regeneration occurs, or when fibrinous exudate cannot be adequately cleared. GO:0097706 vascular endothelial cell response to oscillatory fluid shear stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097706 blood vessel endothelial cell response to oscillatory fluid shear stress Any response to oscillatory fluid shear stress that occurs in a vascular endothelial cell. UBERON:0000070 pupal stage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000070 chrysalis stage|chrysalides stage|pupa stage|aurelia stage A life cycle stage of holometabolous insects in which the organism is a pupa and starts with the larval-pupal apolysis and ends with pupal-adult apolysis. GO:0097707 ferroptosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097707 iron-dependent programmed cell death A programmed cell death characterized morphologically by the presence of smaller than normal mitochondria with condensed mitochondrial membrane densities, reduction or vanishing of mitochondria crista, and outer mitochondrial membrane rupture. Activation of mitochondrial voltage-dependent anion channels and mitogen-activated protein kinases, upregulation of endoplasmic reticulum stress, and inhibition of cystine/glutamate antiporter are involved in the induction of ferroptosis. This process is characterized by the accumulation of lipid peroxidation products and lethal reactive oxygen species (ROS) derived from iron metabolism. Glutathione peroxidase 4 (GPX4), heat shock protein beta-1, and nuclear factor erythroid 2-related factor 2 function as negative regulators of ferroptosis by limiting ROS production and reducing cellular iron uptake, respectively. In contrast, NADPH oxidase and p53 act as positive regulators of ferroptosis by promotion of ROS production and inhibition of expression of SLC7A11 (a specific light-chain subunit of the cystine/glutamate antiporter), respectively. Misregulated ferroptosis has been implicated in multiple physiological and pathological processes. GO:0097704 cellular response to oscillatory fluid shear stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097704 Any response to oscillatory fluid shear stress that occurs at the level of a cell. UBERON:0000079 male reproductive system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000079 male organism genitalia|male genital tract|male genitals|male genital organ|male reproductive tract|genitalia of male organism|male genital system|male organism reproductive system|male genitalia|reproductive system of male organism|systema genitale masculinum The organs associated with producing offspring in the gender that produces spermatozoa. GO:0097705 vascular endothelial cell response to pulsatile fluid shear stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097705 blood vessel endothelial cell response to pulsatile fluid shear stress Any response to pulsatile fluid shear stress that occurs in a vascular endothelial cell. GO:0034180 negative regulation of toll-like receptor 13 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034180 negative regulation of TLR13 signaling pathway|negative regulation of toll-like receptor 13 signalling pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 13 signaling pathway. GO:0097702 response to oscillatory fluid shear stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097702 Any response to fluid shear stress where the fluid is moving across a solid surface with an oscillatory flow. Disturbed flow patterns at the arterial bifurcations and curvatures may cause endothelial dysfunction, which initiates atherosclerosis. GO:0034181 positive regulation of toll-like receptor 13 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034181 positive regulation of TLR13 signaling pathway|positive regulation of toll-like receptor 13 signalling pathway Any process that activates or increases the frequency, rate, or extent of toll-like receptor 13 signaling pathway. GO:0097703 cellular response to pulsatile fluid shear stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097703 Any response to pulsatile fluid shear stress that occurs at the level of a cell. GO:0034182 regulation of maintenance of mitotic sister chromatid cohesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034182 Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle. GO:0097700 vascular endothelial cell response to laminar fluid shear stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097700 blood vessel endothelial cell response to laminar fluid shear stress Any response to laminar fluid shear stress in a vascular endothelial cell. UBERON:0000075 subdivision of skeletal system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000075 skeletal system part|skeletal system subdivision Anatomical cluster consisting of the skeletal elements and articular elements that are part of an individual subdivision of the organism. GO:0034183 negative regulation of maintenance of mitotic sister chromatid cohesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034183 Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle. GO:0097701 response to pulsatile fluid shear stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097701 Any response to fluid shear stress where the fluid is flowing across a solid surface with periodic variations. For example, the endothelium in straight parts of the artery tree is subjected to pulsatile shear stress with a significant forward direction, which is believed to be an important physiological stimulus enhancing vessel compliance and conferring anti-thrombotic, anti-adhesive, and anti-inflammatory effects. UBERON:0000076 external ectoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000076 surface (external) ectoderm|surface ectoderm The surface (external) layer of ectoderm which begins to proliferate shortly after separation from the neuroectoderm. GO:0034184 positive regulation of maintenance of mitotic sister chromatid cohesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034184 Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle. GO:0034185 apolipoprotein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034185 Interacting selectively and non-covalently with an apolipoprotein, the protein component of a lipoprotein complex. UBERON:0000077 mixed endoderm/mesoderm-derived structure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000077 An anatomical structure that develops from the endoderm and the mesoderm. GO:0034186 apolipoprotein A-I binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034186 Interacting selectively and non-covalently with apolipoprotein A-I. UBERON:0000078 mixed ectoderm/mesoderm/endoderm-derived structure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000078 An anatomical structure that develops from the ectoderm, mesoderm and endoderm. GO:0000960 regulation of mitochondrial RNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000960 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome. CHEBI:23399 coumarate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23399 UBERON_CORE:synapsed_by synapsed by biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/uberon/core#synapsed_by synapsed_by Relation between an anatomical structure (including cells) and a neuron that chemically synapses to it. GO:0000961 negative regulation of mitochondrial RNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000961 Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome. GO:0000962 positive regulation of mitochondrial RNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000962 Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome. GO:0000963 mitochondrial RNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000963 The conversion of a primary RNA molecule transcribed from a mitochondrial genome into one or more mature RNA molecules; occurs in the mitochondrion. GO:0048900 anterior lateral line neuromast primordium migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048900 ALL neuromast primordium migration The migration of a cluster of a relatively undifferentiated cell along the developing anterior lateral line, originating from cranial ectodermal placodes situated between the eye and the ear. The neuromast primordium deposits proneuromasts along the lateral line, from which the neuromasts will develop. GO:0048901 anterior lateral line neuromast development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048901 The process whose specific outcome is the progression of the anterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals. CHEBI:23392 corrins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23392 CHEBI:23390 cobalt-corrinoid hexaamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23390 CHEBI:23396 cortisol ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23396 UBERON:0000101 lobe of lung biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000101 lung lobe|pulmonary lobe|pulminory lobe A lung lobe is one of the rounded projections that compose the lung[GO]. GO:0048902 anterior lateral line neuromast deposition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048902 The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in the developing anterior lateral line. GO:0000968 tRNA exon ligation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000968 An RNA exon ligation process that rejoins two exons of a pre-tRNA which has had the intron removed. GO:0000969 tRNA exon ligation utilizing ATP as source of linkage phosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000969 A tRNA exon ligation process in which the splice junction phosphate is derived from exogenous ATP. This type of ligation to rejoin the 5' and 3' exons of a tRNA is observed in vertebrate species. GO:0048903 anterior lateral line neuromast hair cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048903 The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast hair cell. Neuromast hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons. UBERON:0000102 lung vasculature biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000102 lung vascular network|vasculature of lung|pulmonary vasculature|vascular network of lung The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs[GO]. GO:0048904 anterior lateral line neuromast cupula development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048904 The process whose specific outcome is the progression of the anterior lateral line neuromast cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter. UBERON:0000104 life cycle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000104 entire life cycle|lifespan|life|entire lifespan An entire span of an organism's life, commencing with the zygote stage and ending in the death of the organism. GO:0048905 anterior lateral line neuromast mantle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048905 The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast mantle cell. Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded. GO:0000964 mitochondrial RNA 5'-end processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000964 mitochondrial RNA 5' end processing Any process involved in forming the mature 5' end of an RNA molecule transcribed from a mitochondrial genome; occurs in the mitochondrion. GO:0048906 anterior lateral line neuromast support cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048906 The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells. GO:0048907 anterior lateral line ganglion development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048907 gALL development The process whose specific outcome is the progression of the anterior lateral line ganglion over time, from its formation to the mature structure. The anterior lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear. GO:0000965 mitochondrial RNA 3'-end processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000965 mitochondrial RNA 3' end processing Any process involved in forming the mature 3' end of an RNA molecule transcribed from a mitochondrial genome; occurs in the mitochondrion. GO:0000966 RNA 5'-end processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000966 RNA 5' end processing Any process involved in forming the mature 5' end of an RNA molecule. GO:0048908 anterior lateral line ganglion neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048908 The process in which a relatively unspecialized cell acquires specialized features of a neuron of the anterior lateral line ganglion. GO:0000967 rRNA 5'-end processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000967 rRNA 5' end processing Any process involved in forming the mature 5' end of an rRNA molecule. GO:0048909 anterior lateral line nerve development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048909 nALL development|ALLN development|rostral lateral line nerve development The process whose specific outcome is the progression of the anterior lateral line nerve over time, form its formation to the mature structure. The anterior lateral line nerve contains efferent axons that innervate hair cells of the ALL and afferent axons that project to an octavolateralis column in the hindbrain. The octavolateralis column consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus. GO:0000971 tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000971 A tRNA exon ligation process in which the splice junction phosphate is derived from the 2',3' cyclic phosphate at the 3'-end of the 5'-exon. This type of ligation to rejoin the 5' and 3' exons of a tRNA is observed in wheat, Chlamydomonas, and vertebrate species including humans. GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000972 The chromosome organization process in which the DNA sequence containing a gene transcribed by RNA polymerase II is maintained in a specific location at the nuclear periphery. In S. cerevisiae, this process involves cis-acting DNA sequences such as the TATA box and upstream activating sequence (UAS) elements, trans-acting transcriptional activators, and also the 3'-UTR of the transcript. CHEBI:47356 7-chloro-L-tryptophan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47356 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000973 The chromosome organization process in which the DNA sequence containing a gene transcribed by RNA polymerase II is maintained in a specific location at the nuclear periphery even after transcription has been repressed. GO:0000974 Prp19 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000974 Prp19/CDC5 complex|nineteen complex|NTC A protein complex consisting of Prp19 and associated proteins that is involved in the transition from the precatalytic spliceosome to the activated form that catalyzes step 1 of splicing, and which remains associated with the spliceosome through the second catalytic step. It is widely conserved, found in both yeast and mammals, though the exact composition varies. In S. cerevisiae, it contains Prp19p, Ntc20p, Snt309p, Isy1p, Syf2p, Cwc2p, Prp46p, Clf1p, Cef1p, and Syf1p. GO:0048910 afferent axon development in anterior lateral line nerve biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048910 The process whose specific outcome is the progression of an afferent axon in the anterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in the anterior lateral line nerve. GO:0048911 efferent axon development in anterior lateral line nerve biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048911 The process whose specific outcome is the progression of an efferent axon in the anterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in the anterior lateral line nerve. GO:0048912 glial cell migration in anterior lateral line nerve biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048912 The movement of a glial cell along the axons in the anterior lateral line nerve. GO:0000970 tRNA exon ligation utilizing GTP as source of linkage phosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000970 A tRNA exon ligation process in which the splice junction phosphate is derived from exogenous GTP. This type of ligation to rejoin the 5' and 3' exons of a tRNA is observed in the yeast Saccharomyces cerevisiae where the ligation reaction also produces a 2'-phosphate at the splice junction which is subsequently removed as part of the ligation process. CHEBI:86962 veratryl glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86962 CHEBI:86963 veratrylglycerol beta-guaiacyl ether biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86963 GO:0009300 antisense RNA transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009300 The synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA. GO:0009301 snRNA transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009301 The synthesis of small nuclear RNA (snRNA) from a DNA template. GO:0009302 sno(s)RNA transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009302 sRNA transcription|snoRNA transcription The synthesis of snoRNA class RNA (also referred to as sRNA in Archaea) from a DNA template. GO:0009303 rRNA transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009303 rRNA synthesis|rRNA biosynthetic process|rRNA biosynthesis The synthesis of ribosomal RNA (rRNA), any RNA that forms part of the ribosomal structure, from a DNA template. GO:0009304 tRNA transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009304 tRNA synthesis|tRNA biosynthetic process|tRNA biosynthesis The synthesis of transfer RNA (tRNA) from a DNA template. GO:0048913 anterior lateral line nerve glial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048913 The process in which a relatively unspecialized cell acquires specialized features of a glial cell in the anterior lateral line nerve. GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000979 Interacting selectively and non-covalently with a DNA sequence that is part of the core promoter of a RNA polymerase II-transcribed gene. GO:0009305 protein biotinylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009305 protein amino acid biotinylation The addition of biotin (vitamin B7 / vitamin H) to a protein amino acid. GO:0048914 myelination of anterior lateral line nerve axons biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048914 The formation of compact myelin sheaths around the axons of the anterior lateral line nerve. GO:0009306 protein secretion biolink:BiologicalProcess go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0009306 protein secretion resulting in cell fate commitment|protein secretion during cell fate commitment|glycoprotein secretion The controlled release of proteins from a cell. GO:0009307 DNA restriction-modification system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009307 DNA restriction A defense process found in many bacteria and archaea that protects the organism from invading foreign DNA by cleaving it with a restriction endonuclease. The organism's own DNA is protected by methylation of a specific nucleotide, which occurs immediately following replication, in the same target site as the restriction enzyme. GO:0048915 posterior lateral line system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048915 PLL The process whose specific outcome is the progression of the posterior lateral line system over time, from its formation to the mature structure. The posterior lateral line system develops from cranial ectodermal placodes, situated behind the ear, that give rise to both the neuromasts and the posterior lateral line sensory nerves that innervate the neuromasts. The posterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The posterior mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance. GO:0009308 amine metabolic process biolink:BiologicalProcess go-plus goslim_chembl|goslim_pir http://purl.obolibrary.org/obo/GO_0009308 amine metabolism The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. GO:0048916 posterior lateral line development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048916 PLL development The process whose specific outcome is the progression of the posterior lateral line over time, from its formation to the mature structure. The posterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the body and trunk of all fishes and most amphibians. The posterior lateral line develops from cranial ectodermal placodes situated behind the ear. GO:0048917 posterior lateral line ganglion development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048917 gPLL development The process whose specific outcome is the progression of the posterior lateral line ganglion over time, from its formation to the mature structure. The posterior lateral line ganglion develops from cranial ectodermal placodes situated behind the ear. GO:0000975 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000975 GO:0009309 amine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009309 amine biosynthesis|amine anabolism|amine synthesis|amine formation The chemical reactions and pathways resulting in the formation of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. GO:0048918 posterior lateral line nerve development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048918 caudal lateral line nerve development|PLLN development The process whose specific outcome is the progression of the posterior lateral line nerve over time, from its formation to the mature structure. The posterior lateral line nerve innervates hair cells of the PLL and projects to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus. GO:0000976 transcription regulatory region sequence-specific DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000976 transcription regulatory region DNA binding|regulatory region DNA binding Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon. GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000977 RNA polymerase II regulatory region DNA binding Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II. GO:0048919 posterior lateral line neuromast development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048919 The process whose specific outcome is the progression of the posterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals. GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II promoter proximal region sequence-specific DNA binding|RNA polymerase II proximal promoter sequence-specific DNA binding|RNA polymerase II upstream activating sequence (UAS) sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II. CHEBI:72344 alpha-D-kanosamine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72344 CHEBI:23377 copper molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23377 CHEBI:23378 copper cation biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_23378 GO:0000940 condensed chromosome outer kinetochore biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000940 outer kinetochore plate|outer kinetochore of condensed chromosome The region of a condensed chromosome kinetochore most external to centromeric DNA; this outer region mediates kinetochore-microtubule interactions. CHEBI:72346 roseoflavin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72346 CHEBI:23375 copalyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23375 GO:0000941 condensed nuclear chromosome inner kinetochore biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000941 inner kinetochore of condensed nuclear chromosome The region of a condensed nuclear chromosome kinetochore closest to centromeric DNA; this layer may help define underlying centromeric chromatin structure and position of the kinetochore on the chromosome. GO:0048920 posterior lateral line neuromast primordium migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048920 PLL neuromast primordium migration The migration of a relatively undifferentiated cell along the developing posterior lateral line, originating from cranial ectodermal placodes situated behind the ear. The neuromast primordium deposits proneuromasts along the lateral line, from which the neuromasts will develop. GO:0048921 posterior lateral line neuromast cupula development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048921 The process whose specific outcome is the progression of the posterior lateral line neuromast cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter. GO:0048922 posterior lateral line neuromast deposition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048922 The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in the developing posterior lateral line. GO:0048923 posterior lateral line neuromast hair cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048923 The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast hair cell. (N.B. This may be development of neuromast hair cell type or a set of cell of neuromast hair cell type. This will involve the change of a cell or set of cells from one cell identity to another). Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons. UBERON:0014720 interlobar duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014720 intralobular ductule A duct that is located between lobes, within conspicuous, thick connective tissue septa that separate lobes. All interlobar ducts are excretory. CHEBI:86990 N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86990 CHEBI:86991 (R)-fluoxetine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86991 CHEBI:86992 (S)-fluoxetine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86992 CHEBI:86993 (R)-fluoxetine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86993 CHEBI:86994 carboxyphosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86994 CHEBI:86995 (S)-fluoxetine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86995 UBERON:0014717 mucous acinus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014717 acinus of mucuous gland|mucus acinus The secretory unit of a mucous gland. The acinar portion is composed of mucous secreting cells. UBERON:0014719 intralobular duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014719 intralobular ductule A duct that is located within a lobule, with no more connective tissue intervening between ducts and secretory units (i.e., acini or tubules) than between adjacent secretory units. Intercalated and striated ducts are intralobular CHEBI:86999 1-acyl-2-palmitoylglycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86999 UBERON:0014716 interlobular duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014716 A duct that is located between lobules, within the thin connective tissue septa that separate lobules. All interlobular ducts are excretory. GO:0048924 posterior lateral line neuromast mantle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048924 The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast mantle cell. (N.B. This may be development of neuromast mantle cell type or a set of cells of neuromast mantle cell type. This will involve the change of a cell or set of cells from one cell identity to another). Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded. GO:0000946 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000946 GO:0000947 amino acid catabolic process to alcohol via Ehrlich pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000947 The chemical reactions and pathways involving the catabolism of amino acids to produce alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols. GO:0048925 lateral line system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048925 The process whose specific outcome is the progression of the lateral line system over time, from its formation to the mature structure. The lateral line system is a network of sensory organs (neuromasts) and lateral line nerves located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line system develops from cranial ectodermal placodes situated between the eye and ear. GO:0048926 electrosensory lateral line system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048926 The process whose specific outcome is the progression of the electrosensory lateral line system over time, from its formation to the mature structure. GO:0000948 amino acid catabolic process to carboxylic acid via Ehrlich pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000948 The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids. GO:0048927 posterior lateral line neuromast support cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048927 The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells. GO:0000949 aromatic amino acid family catabolic process to alcohol via Ehrlich pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000949 The chemical reactions and pathways involving the catabolism of aromatic amino acids to produce aromatic alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When an aromatic family amino acid, phenylalanine, tyrosine, or tryptophan, is used as the substrate, 2-phenylethanol, 4-hydroxyphenylethanol, or tryptophol, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols. GO:0048928 posterior lateral line ganglion neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048928 The process in which a relatively unspecialized cell acquires specialized features of a neuron of the posterior lateral line ganglion. GO:0000942 condensed nuclear chromosome outer kinetochore biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000942 outer kinetochore of condensed nuclear chromosome The region of a condensed nuclear chromosome kinetochore most external to centromeric DNA; this outer region mediates kinetochore-microtubule interactions. GO:0048929 efferent axon development in posterior lateral line nerve biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048929 The process whose specific outcome is the progression of an efferent axon in the posterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in the posterior lateral line nerve. GO:0000943 retrotransposon nucleocapsid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000943 Wikipedia:Virus-like_particle VLP|Virus-like particle A complex of the retrotransposon RNA genome, reverse transcriptase, integrase, and associated molecules required for reproduction and integration of the retrotransposon into the host genome; the main structural molecule of the nucleocapsid is often a gag protein homolog. GO:0000944 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000944 GO:0000945 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000945 CHEBI:72343 alpha-D-kanosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72343 CHEBI:23388 coproporphyrin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23388 CHEBI:23389 cobalt-corrinoid heptacarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23389 GO:0000950 branched-chain amino acid catabolic process to alcohol via Ehrlich pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000950 branched chain family amino acid catabolic process to alcohol via Ehrlich pathway The chemical reactions and pathways involving the catabolism of branched chain amino acids to produce branched chain alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When a branched chain family amino acid, leucine, isoleucine, or valine, is used as the substrate, 3-methylbutanol, 2-methylbutanol, or 2-methylpropanol, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols. GO:0000951 methionine catabolic process to 3-methylthiopropanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000951 The chemical reactions and pathways involving the catabolism of branched chain amino acids to produce branched chain alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When methionine is used as the substrate, 3-methylthiopropanol is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols. GO:0048930 glial cell migration in posterior lateral line nerve biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048930 The movement of a glial cell along the axons in the posterior lateral line nerve. GO:0000952 aromatic amino acid family catabolic process to carboxylic acid via Ehrlich pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000952 The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When an aromatic family amino acid, phenylalanine, tyrosine, or tryptophan, is used as the substrate, 2-phenylethanoate, 4-hydroxyphenylethanoate, or 2-(Indol-3-yl)-ethanoate, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids. GO:0048931 posterior lateral line nerve glial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048931 The process in which a relatively unspecialized cell acquires specialized features of a glial cell in the posterior lateral line nerve. GO:0048932 myelination of posterior lateral line nerve axons biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048932 The formation of compact myelin sheaths around the axons of the posterior lateral line nerve. GO:0048933 afferent axon development in posterior lateral line nerve biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048933 The process whose specific outcome is the progression of an afferent axon in the posterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in the posterior lateral line nerve. GO:0048934 peripheral nervous system neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048934 The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the peripheral nervous system. CHEBI:86980 diacylglycerol 36:1 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86980 CHEBI:86982 (2R)-2,6-dimethylheptanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86982 CHEBI:86983 (2S)-2,6-dimethylheptanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86983 UBERON:0014706 primitive renal collecting duct system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014706 metanephros primitive collecting ducts|primitive collecting duct CHEBI:86987 diacylglycerol 36:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_86987 UBERON:0014702 frontonasal process epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014702 A epithelium that is part of a frontonasal prominence. UBERON:0014703 anal membrane ectodermal component biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014703 A unilaminar epithelium that develops_from a ectoderm and is part of a anal region. UBERON:0014704 pleuroperitoneal canal lumen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014704 pleuro-peritoneal canal cavity A anatomical space that is enclosed by a pleuroperitoneal canal. UBERON:0014705 median lingual swelling epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014705 tuberculum impar epitheilium A epithelium that is part of a median lingual swelling. GO:0000957 mitochondrial RNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000957 The chemical reactions and pathways resulting in the breakdown of RNA transcribed from the mitochondrial genome and occurring in the mitochondrion. GO:0048935 peripheral nervous system neuron development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048935 The process whose specific outcome is the progression of a neuron whose cell body is located in the peripheral nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron. GO:0000958 mitochondrial mRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000958 The chemical reactions and pathways resulting in the breakdown of mRNA transcribed from the mitochondrial genome and occurring in the mitochondrion. GO:0048936 peripheral nervous system neuron axonogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048936 Generation of a long process from a neuron whose cell body resides in the peripheral nervous system. The axon carries action potential from the cell body towards target cells. GO:0048937 lateral line nerve glial cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048937 The process aimed at the progression of a lateral line glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. GO:0000959 mitochondrial RNA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000959 The chemical reactions and pathways involving RNA transcribed from the mitochondrial genome and occurring in the mitochondrion. GO:0048938 lateral line nerve glial cell morphogenesis involved in differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048938 The process in which the structure of a glial cell in a lateral line nerve is generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in a lateral line nerve. GO:0048939 anterior lateral line nerve glial cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048939 The process aimed at the progression of a glial cell in the anterior lateral line nerve over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. GO:0000953 branched-chain amino acid catabolic process to carboxylic acid via Ehrlich pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000953 branched chain family amino acid catabolic process to carboxylic acid via Ehrlich pathway The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When a branched chain family amino acid, leucine, isoleucine, or valine, is used as the substrate, 3-methylbutanoate, 2-methylbutanoate, or 2-methylpropanoate, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids. GO:0000954 methionine catabolic process to 3-methylthiopropanoate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000954 The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When methionine is used as the substrate, 3-methylthiopropanoate is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids. GO:0000955 amino acid catabolic process via Ehrlich pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000955 The chemical reactions and pathways involving the catabolism of amino acids to produce alcohols or carboxylic acids containing one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives, sometimes referred to as fusel acids, may be produced instead of alcohols. GO:0000956 nuclear-transcribed mRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000956 nuclear mRNA catabolism|nuclear mRNA degradation|nuclear mRNA breakdown The chemical reactions and pathways resulting in the breakdown of nuclear-transcribed mRNAs in eukaryotic cells. CHEBI:23356 S-substituted coenzyme M biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23356 GO:0048940 anterior lateral line nerve glial cell morphogenesis involved in differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048940 The process in which the structures of a glial cell in the anterior lateral line nerve are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in the anterior lateral line nerve. GO:0048941 posterior lateral line nerve glial cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048941 The process aimed at the progression of a glial cell in the posterior lateral line nerve over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. CHEBI:23354 coenzyme biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23354 GO:0048942 posterior lateral line nerve glial cell morphogenesis involved in differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048942 The process in which the structures of a glial cell in the posterior lateral line nerve are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in the posterior lateral line nerve. CHEBI:23357 cofactor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23357 UBERON:0014783 cloacal muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014783 Any muscle organ that is part of a cloaca. CHEBI:37996 organic thiosulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37996 CHEBI:37997 homopolymer macromolecule biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37997 GO:0000928 gamma-tubulin small complex, spindle pole body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000928 Tub4 complex A complex composed of two gamma-tubulin molecules and conserved non-tubulin proteins located in the spindle pole body and isolated by fractionation from cells. The complex, approximately 6S-9S, is analogous to the small complex in animal cells but contains fewer subunits, and is not thought to multimerize into larger functional units, like complexes in those organisms. An example of this structure is found in Saccharomyces cerevisiae. GO:0000929 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000929 CHEBI:37998 glycolithocholic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37998 GO:0000924 gamma-tubulin ring complex, centrosomal biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000924 gamma-tubulin large complex, centrosomal A centrosome-localized multiprotein complex composed of gamma-tubulin and other non-tubulin proteins assembled into a ring structure that is thought to be the unit of nucleation at the minus end of a microtubule. Gamma-tubulin small complexes are thought to be the core repeating units of the ring. GO:0000925 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000925 GO:0000926 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000926 GO:0000927 gamma-tubulin small complex, centrosomal biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000927 A centrosomal complex usually comprising two gamma-tubulin molecules, at least two conserved non-tubulin proteins that multimerize along with additional non-tubulin proteins in animal cells into larger functional complexes. Gamma-tubulin small complexes are thought to be the repeating unit making up the core of the gamma-tubulin ring complex. An example of this structure is found in Mus musculus. GO:0000920 septum digestion after cytokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000920 cell separation following cytokinesis|mitotic cytokinetic cell separation|cell separation after cytokinesis|cytokinetic cell separation|daughter cell separation The process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis. GO:0000921 septin ring assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000921 septin assembly and septum biosynthesis|septin assembly and septum formation The aggregation, arrangement and bonding together of septins and associated proteins to form an organized structure resembling a ring at the cell cortex. GO:0000922 spindle pole biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000922 Either of the ends of a spindle, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules. GO:0000923 equatorial microtubule organizing center biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000923 equatorial microtubule organising centre|EMTOC A microtubule organizing center formed by a band of gamma-tubulin that is recruited to a circumferential band of F-actin at the midpoint of a cell and which nucleates microtubules from the cell division site at the end of mitosis. CHEBI:23366 compatible osmolytes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23366 CHEBI:23367 molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23367 GO:0000930 gamma-tubulin complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0000930 A multiprotein complex composed of gamma-tubulin and other non-tubulin proteins. Gamma-tubulin complexes are localized to microtubule organizing centers, and play an important role in the nucleation of microtubules. The number and complexity of non-tubulin proteins associated with these complexes varies between species. UBERON:0014770 palpebral artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014770 An artery that supplies blood to an eyelid. UBERON:0000127 facial nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000127 facial nerve nucleus|facial VII motor nucleus|facial VII nucleus|nucleus of facial nerve the group of motor neurons residing in the pons that innervate the muscles of facial expression UBERON:0000128 olivary body biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000128 olivary nucleus|olive body|olive|oliva prominent oval structure in the medulla oblongata, present in pairs, the lower portion of the brainstem. They contain the olivary nuclei UBERON:0014775 prosomere biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014775 future prosencephalon|forebrain segment|forebrain neuromere|segment of forebrain A neuromere that is part of the presumptive forebrain UBERON:0014776 midbrain neuromere biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014776 neuromere of mesomere group|future mesencephalon|mesomere of nervous system|segment of midbrain|mesomere group|midbrain segment|mesomere A neuromere that is part of the presumptive midbrain UBERON:0014777 spinal neuromere biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014777 spinal neuromeres|spinal cord segment|spinal cord metameric segment A neuromere that is part of the presumptive spinal cord CHEBI:23360 colitose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_23360 GO:0000939 condensed chromosome inner kinetochore biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000939 inner centromere core complex|inner kinetochore plate|inner kinetochore of condensed chromosome The region of a condensed chromosome kinetochore closest to centromeric DNA; in mammals the CREST antigens (CENP proteins) are found in this layer; this layer may help define underlying centromeric chromatin structure and position of the kinetochore on the chromosome. UBERON:0014769 palpebral vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014769 venae palpebrales|palpebral veins A blood vessel that drains from from an eyelid. GO:0000935 division septum biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000935 complete septum|cell septum surface|divison septum|septum surface A cell septum which forms as part of the division site and functions in the compartmentalization of a cell into two daughter cells at division. A division septum spans a cell and does not allow exchange of organelles or cytoplasm between compartments. GO:0000936 primary cell septum biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000936 primary septum A cell septum that forms following nuclear division. GO:0000937 dolipore septum biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000937 A septum, or cross-wall, between two portions of a cell or hypha; contains a central pore around which the septum is swollen to form a barrel-shaped structure; pore is covered on each side of the septum by a septal pore cap (parenthosome). GO:0000938 GARP complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000938 Golgi associated retrograde protein complex|VFT tethering complex|Vps fifty three tethering complex A quatrefoil tethering complex required for retrograde traffic from the early endosome back to the late Golgi and biogenesis of cytoplasmic vesicles. GO:0000931 gamma-tubulin large complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000931 A complex of gamma tubulin and associated proteins thought to be formed by multimerization of gamma-tubulin small complexes. An example of this structure is found in Schizosaccharomyces pombe. GO:0000932 P-body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000932 Wikipedia:P_body cytoplasmic foci|cytoplasmic mRNA processing body|P body A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing. GO:0000933 adventitious septum biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000933 A cell septum whose formation is independent of nuclear division. GO:0000934 porous cell septum biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000934 porous septum A septum or cross wall which does not entirely span the space between two portions of cell wall and may contain a specialized central pore structure. A porous septum allows the movement of organelles and/or cytoplasm between compartments. CHEBI:72388 lysophosphatidylethanolamine zwitterion 18:1 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72388 CHEBI:23333 cob(III)alamins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23333 CHEBI:72389 lysophosphatidylethanolamine zwitterion 18:2 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72389 CHEBI:23334 cobalamins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23334 UBERON:0000116 lung saccule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000116 Primitive gas exchange portion of the lung composed of type I and type II cells[GO]. UBERON:0000117 respiratory tube biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000117 airway|segment of tracheobronchial tree|respiratory conducting tube|segment of tracheobronchial tree|tracheobronchial tree segment A tube in the respiratory system. Examples: bronchus, bronchiole, trachea. UBERON:0000118 lung bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000118 gemma respiratoria|gemma pulmonalis|respiratory diverticulum|lung bud|primary lung bud Structure derived from foregut that becomes a lung[GO]. UBERON:0000119 cell layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000119 sheath of cells|cell sheath|layer of cells|layer Portion of tissue, that consists of single layer of cells connected to each other by cell junctions. Examples: layer of glial cells; epithelium. CHEBI:23336 cobalt cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23336 UBERON:0014764 anatomical line along groove biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014764 groove|line delineating groove Anatomical line that delineates a furrow or depression in an organ or tissue. UBERON:0014765 crus of diaphragm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014765 crus of the diaphragm|diaphragm crura|crura of the diaphragm|diaphragmatic crura|crural diaphragm The domain of the diaphragm that is located dorsally and attaches to the vertebrae and surrounds the esophagus and aorta. UBERON:0014766 right crus of diaphragm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014766 crus dextrum diaphragmatis|external sphincter of esophagus|right crus of lumbar part of diaphragm|crus dextrum (Diaphragma)|right crus of diaphragm A crus of diaphragm that is in_the_right_side_of a diaphragm. UBERON:0014767 left crus of diaphragm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014767 left crus of diaphragm|crus sinistrum diaphragmatis|left crus of lumbar part of diaphragm|crus sinistrum (Diaphragma) A crus of diaphragm that is in_the_left_side_of a diaphragm. GO:0000906 6,7-dimethyl-8-ribityllumazine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000906 RHEA:26152|EC:2.5.1.78|MetaCyc:LUMAZINESYN-RXN lumazine synthase activity Catalysis of the reaction: 3,4-dihydroxy-2-butanone-4-phosphate + 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione = 6,7-dimethyl-8-ribityllumazine + phosphate. GO:0000907 sulfonate dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000907 sulfonate/alpha-ketoglutarate dioxygenase activity|sulphonate dioxygenase activity Catalysis of the reaction: sulfonate + 2-oxoglutarate + O2 = sulfite + aminoacetaldehyde + succinate + CO2. GO:0000908 taurine dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000908 EC:1.14.11.17|MetaCyc:RXN0-299|RHEA:15909|KEGG_REACTION:R05320 taurine, 2-oxoglutarate:O2 oxidoreductase (sulfite-forming)|2-aminoethanesulfonate dioxygenase activity|alpha-ketoglutarate-dependent taurine dioxygenase activity Catalysis of the reaction: 2-oxoglutarate + O(2) + taurine = aminoacetaldehyde + CO(2) + succinate + sulfite. GO:0000909 sporocarp development involved in sexual reproduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000909 perfect stage fruiting body development|fruiting body development involved in sexual reproduction|ascus development|fruiting body formation involved in sexual reproduction The process whose specific outcome is the progression of a fruiting body organ over time, from its formation to the mature structure. The fruiting body is a spore bearing structure. In fungi, the sporocarp (also known as fruiting body) is a multicellular structure on which spore-producing structures, such as basidia or asci, are borne. The fruiting body is part of the sexual phase of a fungal life cycle, with the rest of the life cycle being characterized by vegetative mycelial growth. The sporocarp of a basidiomycete is known as a basidiocarp, while the fruiting body of an ascomycete is known as an ascocarp. A significant range of different shapes and morphologies is found in both basidiocarps and ascocarps; these features play an important role in the identification and taxonomy of fungi. GO:0000902 cell morphogenesis biolink:BiologicalProcess go-plus goslim_generic|goslim_chembl|goslim_yeast|goslim_drosophila http://purl.obolibrary.org/obo/GO_0000902 cellular morphogenesis The developmental process in which the size or shape of a cell is generated and organized. CHEBI:72381 lysophosphatidylethanolamine zwitterion 14:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72381 GO:0000903 obsolete regulation of cell shape during vegetative growth phase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000903 cell morphogenesis during vegetative growth phase|regulation of cell morphogenesis during vegetative growth phase|cellular morphogenesis during vegetative growth OBSOLETE. Any process that modulates the surface configuration of a cell during the vegetative growth phase. The vegetative growth phase is the growth phase during which single celled organisms reproduce by budding or other asexual methods. GO:0000904 cell morphogenesis involved in differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000904 The change in form (cell shape and size) that occurs when relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. UBERON:0000125 neural nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000125 nervous system nucleus|nucleus of neuraxis|nucleus of CNS|nucleus|neuraxis nucleus|neuronal nucleus A spatially aggregated collection of nerve cell bodies in the CNS, consisting of one or more subpopulations that share cell type, chemical phenotype, and connections, and including nearby cells that share the same cell type, chemical phenotype, and connections. (CUMBO) GO:0000905 sporocarp development involved in asexual reproduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000905 fruiting body formation involved in asexual reproduction|imperfect stage fruiting body development|haploid fruiting|monokaryotic fruiting|conidium development|homokaryotic fruiting The formation of a spore-bearing structure by fungus where spores will arise from asexual reproduction. UBERON:0000126 cranial nerve nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000126 nucleus of cranial nerve|nucleus nervi cranialis|cranial neural nucleus Nucleus that receives projections from or contains neurons that send projections through one of the cranial nerves CHEBI:72384 lysophosphatidylethanolamine zwitterion 16:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72384 UBERON:0000120 blood brain barrier biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000120 BBB|blood-brain barrier Cell layer consisting of lining cells that separates the central nervous system and the bloodstream. The BBB may consist of endothelial cells or glial cells. An endothelial barrier may have arisen independently several times during evolution. In bichir and lungfish the barrier is formed by brain endothelial cells, while in sturgeon it is formed by a complex perivascular glial sheath, but with no detectable tight junctions. GO:0000900 translation repressor activity, mRNA regulatory element binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000900 translation repressor activity, nucleic acid binding Antagonizes the ribosome-mediated translation of mRNA into a polypeptide via direct binding (through a selective and non-covalent interaction) to nucleic acid. UBERON:0000122 neuron projection bundle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000122 funiculus|nerve fiber bundle|neural fiber bundle A fasciculated bundle of neuron projections (GO:0043005), largely or completely lacking synapses. CHEBI:72387 lysophosphatidylethanolamine zwitterion 18:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72387 GO:0000901 translation repressor activity, non-nucleic acid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000901 Antagonizes the ribosome-mediated translation of mRNA into a polypeptide but does not bind directly to nucleic acid. UBERON:0000109 gastrula stage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000109 trilaminar disk stage|trilaminar germ stage|blastocystis trilaminaris stage|trilaminar blastoderm stage|trilaminar blastocyst stage|trilaminar stage A stage defined by complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm. GO:1902807 negative regulation of cell cycle G1/S phase transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902807 down-regulation of cell cycle G1/S phase transition|downregulation of cell cycle G1/S phase transition|down regulation of cell cycle G1/S phase transition|inhibition of cell cycle G1/S phase transition Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle. GO:1902808 positive regulation of cell cycle G1/S phase transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902808 up-regulation of cell cycle G1/S phase transition|activation of cell cycle G1/S phase transition|up regulation of cell cycle G1/S phase transition|upregulation of cell cycle G1/S phase transition Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle. CHEBI:23345 cobyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23345 GO:1902805 positive regulation of synaptic vesicle transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902805 activation of synaptic vesicle transport|up-regulation of synaptic vesicle transport|upregulation of synaptic vesicle fission|up regulation of synaptic vesicle fusion|positive regulation of synaptic vesicle fusion|up-regulation of synaptic vesicle fission|activation of synaptic vesicle fusion|up regulation of synaptic vesicle transport|activation of synaptic vesicle fission|up-regulation of synaptic vesicle fusion|positive regulation of synaptic vesicle fission|up regulation of synaptic vesicle fission|upregulation of synaptic vesicle transport|upregulation of synaptic vesicle fusion Any process that activates or increases the frequency, rate or extent of synaptic vesicle transport. GO:1902806 regulation of cell cycle G1/S phase transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902806 Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle. GO:1902803 regulation of synaptic vesicle transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902803 regulation of synaptic vesicle fission|regulation of synaptic vesicle fusion Any process that modulates the frequency, rate or extent of synaptic vesicle transport. UBERON:0000105 life cycle stage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000105 developmental stage|stage A spatiotemporal region encompassing some part of the life cycle of an organism. UBERON:0000106 zygote stage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000106 zygote|fertilized egg stage|one-cell stage|zygotum|1-cell stage|one cell stage|fertilized egg stage A stage at which the organism is a single cell produced by means of sexual reproduction. GO:1902804 negative regulation of synaptic vesicle transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902804 inhibition of synaptic vesicle fission|down-regulation of synaptic vesicle transport|down-regulation of synaptic vesicle fusion|negative regulation of synaptic vesicle fusion|negative regulation of synaptic vesicle fission|down-regulation of synaptic vesicle fission|downregulation of synaptic vesicle transport|down regulation of synaptic vesicle transport|inhibition of synaptic vesicle fusion|inhibition of synaptic vesicle transport|downregulation of synaptic vesicle fission|down regulation of synaptic vesicle fusion|down regulation of synaptic vesicle fission|downregulation of synaptic vesicle fusion Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle transport. GO:1902801 regulation of heterochromatin island assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902801 regulation of heterochromatin island formation Any process that modulates the frequency, rate or extent of heterochromatin island assembly. UBERON:0000107 cleavage stage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000107 The first few specialized divisions of an activated animal egg; Stage consisting of division of cells in the early embryo. The zygotes of many species undergo rapid cell cycles with no significant growth, producing a cluster of cells the same size as the original zygote. The different cells derived from cleavage are called blastomeres and form a compact mass called the morula. Cleavage ends with the formation of the blastula. GO:1902802 regulation of heterochromatin domain assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902802 regulation of HOOD assembly|regulation of heterochromatin domain formation|regulation of HOOD formation Any process that modulates the frequency, rate or extent of heterochromatin domain assembly. UBERON:0000108 blastula stage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000108 An early stage of embryonic development in animals. It is produced by cleavage of a fertilized ovum and consists of a spherical layer of around 128 cells surrounding a central fluid-filled cavity called the blastocoel. The blastula follows the morula and precedes the gastrula in the developmental sequence. CHEBI:23347 coclaurine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23347 GO:1902800 positive regulation of phosphodiesterase I activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902800 positive regulation of 5'-nucleotide phosphodiesterase activity|up-regulation of oligonucleate 5'-nucleotidohydrolase activity|activation of PDE I activity|upregulation of 5'-PDase activity|positive regulation of 5'-NPDase activity|up regulation of 5'-nucleotide phosphodiesterase activity|upregulation of 5'-phosphodiesterase activity|activation of 5'NPDE activity|up regulation of 5'-NPDase activity|activation of alkaline phosphodiesterase activity|upregulation of exonuclease I activity|activation of 5'-PDE activity|upregulation of phosphodiesterase I activity|up regulation of 5'-exonuclease activity|upregulation of 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity|up regulation of orthophosphoric diester phosphohydrolase activity|positive regulation of 5'-exonuclease activity|upregulation of nucleotide pyrophosphatase/phosphodiesterase I activity|positive regulation of orthophosphoric diester phosphohydrolase activity|activation of orthophosphoric diester phosphohydrolase activity|up-regulation of alkaline phosphodiesterase activity|up-regulation of 5'NPDE activity|upregulation of oligonucleate 5'-nucleotidohydrolase activity|positive regulation of PDE I activity|up-regulation of 5'-PDE activity|up regulation of 5'-PDase activity|up regulation of PDE I activity|up regulation of 5'-phosphodiesterase activity|upregulation of 5'-nucleotide phosphodiesterase activity|positive regulation of 5'-PDase activity|up-regulation of exonuclease I activity|upregulation of 5'-NPDase activity|activation of 5'-exonuclease activity|up-regulation of phosphodiesterase I activity|positive regulation of 5'-phosphodiesterase activity|activation of phosphodiesterase I activity|up regulation of 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity|up regulation of nucleotide pyrophosphatase/phosphodiesterase I activity|upregulation of alkaline phosphodiesterase activity|activation of 5'-PDase activity|upregulation of 5'NPDE activity|activation of 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity|positive regulation of 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity|activation of exonuclease I activity|up-regulation of 5'-exonuclease activity|activation of 5'-phosphodiesterase activity|up regulation of oligonucleate 5'-nucleotidohydrolase activity|upregulation of 5'-PDE activity|positive regulation of nucleotide pyrophosphatase/phosphodiesterase I activity|activation of nucleotide pyrophosphatase/phosphodiesterase I activity|up-regulation of orthophosphoric diester phosphohydrolase activity|activation of oligonucleate 5'-nucleotidohydrolase activity|positive regulation of oligonucleate 5'-nucleotidohydrolase activity|up-regulation of 5'-nucleotide phosphodiesterase activity|up-regulation of 5'-NPDase activity|upregulation of PDE I activity|positive regulation of exonuclease I activity|up-regulation of 5'-PDase activity|up-regulation of 5'-phosphodiesterase activity|up regulation of exonuclease I activity|activation of 5'-nucleotide phosphodiesterase activity|up regulation of phosphodiesterase I activity|up regulation of alkaline phosphodiesterase activity|activation of 5'-NPDase activity|up regulation of 5'NPDE activity|upregulation of 5'-exonuclease activity|upregulation of orthophosphoric diester phosphohydrolase activity|up regulation of 5'-PDE activity|positive regulation of 5'NPDE activity|up-regulation of 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity|positive regulation of alkaline phosphodiesterase activity|positive regulation of 5'-PDE activity|up-regulation of PDE I activity|up-regulation of nucleotide pyrophosphatase/phosphodiesterase I activity Any process that activates or increases the frequency, rate or extent of phosphodiesterase I activity. CHEBI:23341 cobamides biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23341 CHEBI:37986 1-(3-O-sulfo-beta-D-galactosyl-(1->4)-beta-D-glucosyl)-N-acylsphingosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37986 GO:0000917 division septum assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000917 division septum formation|division septum assembly involved in cell cycle cytokinesis involved in mitotic cell cycle|septin assembly and septum formation involved in mitotic cell cycle|septin assembly and septum biosynthesis involved in mitotic cell cycle|formation of division septum|formation of division septum involved in mitotic cell cycle|division septum assembly involved in cell cycle cytokinesis|septin assembly and septum biosynthesis|division septum formation involved in cell cycle cytokinesis involved in mitotic cell cycle|septin assembly and septum formation|division septum formation involved in mitotic cell cycle|division septum formation involved in cell cycle cytokinesis|septation|mitotic division septum assembly The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material. GO:0000918 division septum site selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000918 septin assembly and septum formation|septum positioning|selection of site for barrier cell septum biosynthesis|selection of site for barrier cell septum formation|selection of site for division septum formation|septin assembly and septum biosynthesis The process of marking the site where a division septum will form. GO:0000919 cell plate assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000919 cell plate formation The process of assembly, maturation, and growth of the cell plate to the cell periphery in cells that divide by cell plate formation; often involves deposition of cell wall material in and around the phragmoplast. UBERON:0000112 sexually immature stage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000112 subadult stage|juvenile stage|immature stage GO:0000913 preprophase band assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000913 preprophase band formation The aggregation, arrangement and bonding together of a set of components to form the preprophase band, a dense band of microtubules that marks the position in the cell where cytokinesis will occur in cells that perform cytokinesis by cell plate formation. GO:0000914 phragmoplast assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000914 phragmoplast formation The formation of a structure composed of actin, myosin, and associated proteins that will function in cytokinesis in cells that perform cytokinesis by cell plate formation. The structure usually contains antiparallel microtubules and membrane (often visible as vesicles). UBERON:0000113 post-juvenile adult stage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000113 adult stage The stage of being a sexually mature adult animal. GO:0000915 actomyosin contractile ring assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000915 cytokinesis, actomyosin contractile ring assembly|cytokinesis, actomyosin contractile ring formation|cytokinesis, actomyosin ring formation|constriction ring assembly|contractile ring assembly|cytokinesis, actomyosin ring biosynthesis|cytokinesis, contractile ring assembly The process of assembly of a ring composed of actin, myosin, and associated proteins that will function in cytokinesis. UBERON:0000114 lung connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000114 pulmonary interstitial tissue|lung interstitial tissue|pulmonary interstitium|pulmonary connective tissue|lung interstitium|connective tissue of lung the connective tissue located between the respiratory (airway and alveolar) epithelium, the capillary endothelium and pleural mesothelium; it contains basement membrane composed of collagen, elastin, proteoglycans, and fibronectin GO:0000916 actomyosin contractile ring contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000916 cytokinesis, actomyosin ring contraction|contractile ring constriction|cytokinesis, contractile ring contraction|contractile ring contraction involved in cell cycle cytokinesis The process of an actomyosin ring getting smaller in diameter, in the context of cytokinesis that takes place as part of a cell cycle. UBERON:0000115 lung epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000115 pulmonary epithelium|epithelial tissue of lung|epithelium of lung|lung epithelial tissue The epithelial layer of the lung. GO:0000910 cytokinesis biolink:BiologicalProcess go-plus goslim_yeast|goslim_candida|gocheck_do_not_manually_annotate|goslim_aspergillus http://purl.obolibrary.org/obo/GO_0000910 Wikipedia:Cytokinesis cell cycle cytokinesis|cytokinesis involved in cell cycle The division of the cytoplasm and the plasma membrane of a cell and its partitioning into two daughter cells. GO:0000911 cytokinesis by cell plate formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000911 The process of dividing the cytoplasm of a parent cell where a structure forms in the cytoplasm and grows until reaching the plasma membrane, thereby completely separating the cytoplasms of adjacent progeny cells. An example of this is found in Arabidopsis thaliana. GO:1902809 regulation of skeletal muscle fiber differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902809 Any process that modulates the frequency, rate or extent of skeletal muscle fiber differentiation. UBERON:0000110 neurula stage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000110 Staged defined by the formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system. GO:0000912 assembly of actomyosin apparatus involved in cytokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000912 cytokinesis, formation of actomyosin apparatus|actomyosin apparatus assembly involved in cytokinesis|formation of actomyosin apparatus involved in cytokinesis The assembly and arrangement of an apparatus composed of actin, myosin, and associated proteins that will function in cytokinesis. UBERON:0000111 organogenesis stage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000111 segmentation stage A stage at which the ectoderm, endoderm, and mesoderm develop into the internal organs of the organism. GO:0034338 short-chain carboxylesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034338 butyrate esterase activity|propionyl esterase activity|methylbutyrate esterase activity|butyryl esterase activity|methylbutyrase activity|monobutyrase activity|short-chain esterase activity Catalysis of the reaction: a carboxylic ester + H2O = an alcohol + a carboxylic anion, where the carboxylic chain has 8 or fewer carbon atoms. GO:0034339 obsolete regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor OBSOLETE. Any process in which a ligand-bound hormone receptor acts in the nucleus to modulate the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:0010369 chromocenter biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0010369 A region in which centric, heterochromatic portions from more than one chromosomes form a compact structure. GO:0009380 excinuclease repair complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009380 excinuclease ABC complex|UvrABC excinuclease complex Any of the protein complexes formed by the UvrABC excinuclease system, which carries out nucleotide excision repair. Three different complexes are formed by the 3 proteins as they proceed through the excision repair process. First a complex consisting of two A subunits and two B subunits bind DNA and unwind it around the damaged site. Then, the A subunits disassociate leaving behind a stable complex between B subunits and DNA. Now, subunit C binds to this B+DNA complex and causes subunit B to nick the DNA on one side of the complex while subunit C nicks the DNA on the other side of the complex. DNA polymerase I and DNA ligase can then repair the resulting gap. GO:0009381 excinuclease ABC activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009381 Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid at sites flanking regions of damaged DNA to which the Uvr ABC excinuclease complexes bind. GO:0009382 imidazoleglycerol-phosphate synthase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009382 imidazoleglycerol phosphate synthase complex Complex that possesses imidazoleglycerol-phosphate synthase activity. GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009383 Reactome:R-HSA-6793057|Reactome:R-HSA-6790944 rRNA (cytosine-C5-967)-methyltransferase activity|rRNA m5C967 methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to cytosine to form 5-methylcytosine in small subunit ribosomal RNA. GO:0009384 N-acylmannosamine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009384 EC:2.7.1.60|Reactome:R-HSA-4085028|MetaCyc:N-ACYLMANNOSAMINE-KINASE-RXN|Reactome:R-HSA-4088322|RHEA:23832 acylmannosamine kinase (phosphorylating)|ATP:N-acetylmannosamine 6-phosphotransferase activity|N-acyl-D-mannosamine kinase activity|N-acetylmannosamine kinase activity|acetylmannosamine kinase activity|ATP:N-acyl-D-mannosamine 6-phosphotransferase activity|acetylamidodeoxymannokinase activity|acylaminodeoxymannokinase activity|acylmannosamine kinase activity Catalysis of the reaction: ATP + N-acyl-D-mannosamine = ADP + N-acyl-D-mannosamine 6-phosphate. GO:0034330 cell junction organization biolink:BiologicalProcess go-plus goslim_generic|goslim_chembl http://purl.obolibrary.org/obo/GO_0034330 cell junction biogenesis|cell junction organisation|cell junction assembly and maintenance A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell junction. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix. GO:0009374 biotin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009374 vitamin H binding|vitamin B7 binding Interacting selectively and non-covalently with biotin (cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid), the (+) enantiomer of which is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions. GO:0010363 regulation of plant-type hypersensitive response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010363 regulation of plant hypersensitive response|regulation of HR-PCD|regulation of HR Any endogenous process that modulates the frequency, rate or extent of the plant hypersensitive response. GO:0034331 cell junction maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034331 The organization process that preserves a cell junction in a stable functional or structural state. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix. GO:0009375 ferredoxin hydrogenase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009375 hydrogenase complex An enzyme complex that catalyzes the oxidation of reduced ferredoxin. Hydrogenase contains iron-sulfur clusters, and some contain nickel; it can use molecular hydrogen for the reduction of a variety of substances. CHEBI:62920 icosatetraenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62920 GO:0010364 regulation of ethylene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010364 Any process that modulates the frequency, rate, or extent of an ethylene biosynthetic process. GO:0010361 regulation of anion channel activity by blue light biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010361 regulation by blue light of anion channel activity Any process in which blue light modulates the frequency, rate or extent of anion channel activity. GO:0009376 HslUV protease complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009376 ClpYQ protease complex A protein complex that possesses ATP-dependent protease activity; consists of an ATPase large subunit with homology to other ClpX family ATPases and a peptidase small subunit related to the proteasomal beta-subunits of eukaryotes. In the E. coli complex, a double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. GO:0034332 adherens junction organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034332 adherens junction organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments. GO:0010362 negative regulation of anion channel activity by blue light biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010362 inhibition by blue light of anion channel activity|negative regulation by blue light of anion channel activity Any process in which blue light stops, prevents, or reduces the frequency, rate, or extent of the anion channel activity. GO:0034333 adherens junction assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034333 adherens junction formation The aggregation, arrangement and bonding together of a set of components to form an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments. GO:0009377 obsolete HslUV protease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009377 HslUV protease activity OBSOLETE. Catalysis of the ATP-dependent hydrolysis of peptide bonds in substrates including E. coli SulA and misfolded proteins. GO:0034334 adherens junction maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034334 The maintenance of an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments. GO:0009378 four-way junction helicase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009378 ATP-dependent four-way junction helicase activity|ATP-dependent four-way junction DNA helicase activity|ATP-dependent Holliday junction helicase activity|Holliday junction helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate, where this reaction drives the unwinding of the DNA helix of DNA containing four-way junctions, including Holliday junctions. CHEBI:62923 1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62923 GO:0010367 extracellular isoamylase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0010367 A protein complex whose composition varies amongst species; in rice it probably exists in a homo-tetramer to homo-hexamer form and in Gram negative bacteria as a dimer. Functions in the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages. Isoamylases in animals are localized in the extracellular space. GO:0010368 chloroplast isoamylase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0010368 A protein complex whose composition varies amongst species; in rice it probably exists in a homo-tetramer to homo-hexamer form and in Gram negative bacteria as a dimer. Functions in the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages. Isoamylases in plants are intracellular and probably chloroplast localized. GO:0009379 Holliday junction helicase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009379 A DNA helicase complex found at Holliday junctions where the helicase activity is involved in the migration of the junction branch point. The best-characterized example is the E. coli RuvAB complex, in which a hexamer of RuvB subunits possesses helicase activity that is modulated by association with RuvA. GO:0034335 DNA negative supercoiling activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034335 DNA-gyrase activity|DNA gyrase activity Catalytic introduction of negative supercoils into a DNA molecule or region thereof. In bacteria, negative supercoils are only introduced by DNA gyrase, a type II topoisomerase, but not all DNA gyrases are capable of introducing supercoils. In bacteria, the level of supercoiling varies widely between species and has been characterized properly in only a handful of organisms. The best characterized enzyme, from E.coli, is exceptionally proficient at supercoiling and this ability is not representative of all bacteria. CHEBI:62924 3,5-bis(diphospho)-1D-myo-inositol 1,2,4,6-tetrakisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62924 CHEBI:62921 (S,S,S)-nicotianamine monoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62921 GO:0034336 misfolded RNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034336 RNA chaperone Interacting selectively and non-covalently with an RNA molecule that has assumed an incorrect conformation. GO:0010365 positive regulation of ethylene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010365 Any process that activates or increases the frequency, rate or extent of an ethylene biosynthetic process. GO:0010366 negative regulation of ethylene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010366 Any process that stops, prevents, or reduces the frequency, rate or extent of an ethylene biosynthetic process. GO:0034337 RNA folding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034337 RNA chaperone The process of assisting in the covalent and noncovalent assembly of single or multimeric RNAs into the correct tertiary structure. CHEBI:62922 3-diphospho-1D-myo-inositol 1,2,4,5,6-pentakisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62922 CHEBI:139036 ent-Photinus luciferin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139036 CHEBI:139032 nerylneryl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139032 GO:0010360 negative regulation of anion channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010360 Any process that stops, prevents, or reduces the frequency, rate, or extent of the anion channel activity. CHEBI:139033 (-)-kolavenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139033 CHEBI:139034 (+)-kolavenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139034 CHEBI:139035 L-firefly luciferyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139035 CHEBI:139051 phytoceramide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139051 CHEBI:139052 inositol-1-phosphodihydroceramide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139052 CHEBI:139053 inositol-1-phosphophytoceramide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139053 GO:0034327 hexanoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034327 Catalysis of the transfer of a hexanoyl (CH3-[CH2]4-CO-) group to an acceptor molecule. GO:0034328 decanoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034328 Catalysis of the transfer of a decanoyl (CH3-[CH2]8-CO-) group to an acceptor molecule. GO:0034329 cell junction assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034329 A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a cell junction. GO:0009390 dimethyl sulfoxide reductase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009390 dimethyl sulphoxide reductase complex An enzyme complex that catalyzes the formation of dimethyl sulfide from dimethyl sulfoxide. GO:0009391 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009391 GO:0009392 N-acetyl-anhydromuramoyl-L-alanine amidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009392 MetaCyc:RXN0-5225 Catalysis of the reaction: GlcNAc-1,6-anhMurNAc-L-Ala-gamma-D-Glu-DAP-D-Ala + H2O glcNAc-1,6-anhMurNAc + L-Ala-gamma-D-Glu-DAP-D-Ala. GO:0009393 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009393 GO:0009394 2'-deoxyribonucleotide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009394 2'-deoxyribonucleotide metabolism The chemical reactions and pathways involving a 2'-deoxyribonucleotide, a compound consisting of 2'-deoxyribonucleoside (a base linked to a 2'-deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. GO:0009395 phospholipid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009395 phospholipid catabolism|phospholipid degradation|phospholipid breakdown The chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester. GO:0009385 N-acylmannosamine-6-phosphate 2-epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009385 EC:5.1.3.9|RHEA:25257|MetaCyc:NANE-RXN N-acylmannosamine-6-P epimerase activity Catalysis of the reaction: N-acetyl-D-mannosamine-6-phosphate = N-acetyl-D-glucosamine-6-phosphate. GO:0010374 stomatal complex development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010374 The process whose specific outcome is the progression of the stomatal complex over time from its formation to the mature structure. The stomatal complex is the stomatal guard cells and their associated epidermal cells. GO:0009386 translational attenuation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009386 Translational attenuation is a regulatory mechanism analogous to ribosome-mediated transcriptional attenuation. The system requires the presence of a short ORF, called a leader peptide, encoded in the mRNA upstream of the ribosome-binding site and start codon of the gene whose translation is to be regulated. Certain conditions, such as presence of the antibiotic tetracycline in bacteria or amino acid starvation, may cause slowing or stalling of the ribosome translating the leader peptide. The stalled ribosome masks a region of the mRNA and affects which of two alternative mRNA folded structures will form, therefore controlling whether or not a ribosome will bind and initiate translation of the downstream gene. Translational attenuation is analogous to ribosome-mediated transcriptional attenuation, in which mRNA remodeling caused by ribosome stalling regulates transcriptional termination rather than translational initiation. GO:0010375 stomatal complex patterning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010375 The regionalization process of establishing the non-random spatial arrangement of stomatal complex on the surface of a leaf. The stomatal complex is the stomatal guard cells and their associated epidermal cells. GO:0034320 alcohol O-hexanoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034320 Catalysis of the reaction: hexanoyl-CoA + an alcohol = CoA + a hexyl ester. GO:0010372 positive regulation of gibberellin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010372 positive regulation of gibberellic acid biosynthetic process Any process that activates, maintains or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins. GO:0009387 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009387 GO:0034321 alcohol O-octanoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034321 Catalysis of the reaction: octanoyl-CoA + an alcohol = CoA + an octyl ester. GO:0009388 obsolete antisense RNA biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009388 antisense RNA OBSOLETE. (Was not defined before being made obsolete). GO:0010373 negative regulation of gibberellin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010373 negative regulation of gibberellic acid biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins. GO:0034322 alcohol O-decanoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034322 Catalysis of the reaction: decanoyl-CoA + an alcohol = CoA + a decyl ester. GO:0009389 dimethyl sulfoxide reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009389 EC:1.8.99.-|UM-BBD_reactionID:r0207 dimethyl sulphoxide reductase activity Catalysis of the reaction: dimethyl sulfoxide + H+ = dimethyl sulfide + H2O. GO:0010378 temperature compensation of the circadian clock biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010378 regulation of the circadian clock by temperature The process in which the circadian clock maintains robust and accurate timing over a broad range of physiological temperatures. The circadian clock is an endogenous 24-h timer found in most eukaryotes and in photosynthetic bacteria. The clock drives rhythms in the physiology, biochemistry, and metabolism of the organisms. GO:0034323 O-butanoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034323 Catalysis of the transfer of a butyl group to an oxygen atom on the acceptor molecule. CHEBI:62934 discadenine(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62934 GO:0034324 O-hexanoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034324 Catalysis of the transfer of a hexyl group to an oxygen atom on the acceptor molecule. GO:0010379 phaseic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010379 MetaCyc:PWY-5271 The chemical reactions and pathways resulting in the formation of phaseic acid (PA), a catabolite of the plant hormone abscisic acid (ABA). GO:0034325 O-decanoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034325 Catalysis of the transfer of a decyl group to an oxygen atom on the acceptor molecule. GO:0010376 stomatal complex formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010376 The process that gives rise to the stomatal complex. This process pertains to the initial formation of a structure from unspecified parts. The stomatal complex is the stomatal guard cells and their associated epidermal cells. CHEBI:62932 mycophenolate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62932 GO:0010377 guard cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010377 stomatal cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a stomatal guard cell. Guard cells are located in the leaf epidermis and pairwise surround stomatal pores, which allow CO2 influx for photosynthetic carbon fixation and water loss via transpiration to the atmosphere. GO:0034326 butanoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034326 Catalysis of the transfer of a butanoyl (CH3-[CH2]2-CO-) group to an acceptor molecule. CHEBI:62933 oxylipin anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62933 CHEBI:62938 hepoxilin anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62938 CHEBI:139048 dihydroceramide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139048 CHEBI:62936 homomethioninate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62936 CHEBI:62937 icosanoid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62937 GO:0010370 perinucleolar chromocenter biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0010370 A chromocenter adjacent to the nucleolus. GO:0010371 regulation of gibberellin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010371 regulation of gibberellic acid biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins. CHEBI:139020 taurino group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139020 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034316 Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins. GO:0010349 L-galactose dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010349 MetaCyc:RXN-1884|RHEA:31559 L-galactose 1-dehydrogenase activity Catalysis of the reaction: L-galactose + NAD+ = L-galactono-1,4-lactone + NADH + H+. GO:0034317 nicotinic acid riboside kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034317 MetaCyc:RXN-8443 Catalysis of the reaction: ATP + nicotinic acid riboside = ADP + nicotinic acid mononucleotide. GO:0034318 alcohol O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034318 alcohol acyltransferase activity|acyl-CoA:alcohol O-acyltransferase activity|acyl-coenzymeA:alcohol O-acyltransferase activity|acyl-CoA:ethanol O-acyltransferase|acyl-coenzymeA:ethanol O-acyltransferase activity|AEATase activity Catalysis of the transfer of an acyl group to an oxygen atom on an alcohol acceptor molecule. GO:0010347 L-galactose-1-phosphate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010347 MetaCyc:RXNQT-4142|RHEA:26349 Catalysis of the reaction: L-galactose-1-phosphate + H2O = L-galactose + phosphate. GO:0034319 alcohol O-butanoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034319 Catalysis of the reaction: butanoyl-CoA + an alcohol = CoA + a butyl ester. GO:0010348 lithium:proton antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010348 lithium:hydrogen antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Li+(in) + H+(out) = Li+(out) + H+(in). GO:0009360 DNA polymerase III complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009360 DNA polymerase III holoenzyme complex The DNA polymerase III holoenzyme is a complex that contains 10 different types of subunits. These subunits are organized into 3 functionally essential sub-assemblies: the pol III core, the beta sliding clamp processivity factor and the clamp-loading complex. The pol III core carries out the polymerase and the 3'-5' exonuclease proofreading activities. The polymerase is tethered to the template via the sliding clamp processivity factor. The clamp-loading complex assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork. GO:0009361 succinate-CoA ligase complex (ADP-forming) biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009361 succinyl-CoA synthetase, ADP-forming A heterodimeric enzyme complex, composed of an alpha and beta chain, most usually found in (but not limited to) bacteria. Functions in the TCA cycle, hydrolyzing succinyl-CoA into succinate and CoA, thereby forming ATP. GO:0009362 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009362 GO:0009352 obsolete dihydrolipoyl dehydrogenase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009352 dihydrolipoyl dehydrogenase complex|dihydrolipoamide dehydrogenase complex OBSOLETE. Complex that possesses dihydrolipoyl dehydrogenase activity. CHEBI:62941 glycosylceramide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62941 GO:0010341 gibberellin carboxyl-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010341 Catalysis of the reaction: S-adenosyl-L-methionine + a gibberellin = S-adenosyl-L-homocysteine + a gibberellin methyl ester. GO:0010342 endosperm cellularization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010342 cellularization of endosperm The separation of the multi-nucleate endosperm into individual cells. In many plant species, the endosperm that nurtures the embryo in the seed initially develops as a syncytium. This syncytial phase ends with simultaneous partitioning of the multi-nucleate cytoplasm into individual cells, a process referred to as cellularization. CHEBI:62942 leukotriene anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62942 GO:0009353 mitochondrial oxoglutarate dehydrogenase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009353 A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix. An example of this complex is found in Mus musculus. GO:0034310 primary alcohol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034310 primary alcohol breakdown|monohydric alcohol catabolic process|primary alcohol catabolism|primary alcohol degradation The chemical reactions and pathways resulting in the breakdown of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it. GO:0009354 obsolete dihydrolipoamide S-succinyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009354 dihydrolipoamide S-succinyltransferase complex OBSOLETE. An enzyme complex that catalyzes the transfer of succinyl-CoA to dihydrolipoamide to form S-succinyldihydrolipoamide. The enzyme is a component of the multienzyme 2-oxoglutarate dehydrogenase complex. CHEBI:86910 N-acetylhistidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_86910 GO:0034311 diol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034311 dihydric alcohol metabolic process|diol metabolism The chemical reactions and pathways involving a diol, a compound that contains two hydroxy groups, generally assumed to be, but not necessarily, alcoholic. GO:0010340 carboxyl-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010340 Catalysis of the transfer of a methyl group to the carboxyl group of an acceptor molecule to form a methyl ester. GO:0009355 DNA polymerase V complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009355 A DNA polymerase complex that contains two UmuD' and one UmuC subunits, and acts in translesion DNA synthesis. GO:0034312 diol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034312 diol biosynthesis|dihydric alcohol biosynthetic process|diol anabolism|diol synthesis|diol formation The chemical reactions and pathways resulting in the formation of a diol, any alcohol containing two hydroxyl groups attached to saturated carbon atoms. CHEBI:62945 thromboxane anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62945 GO:0009356 aminodeoxychorismate synthase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009356 p-aminobenzoate synthetase complex|4-amino-4-deoxychorismate synthase complex|ADC synthase complex A heterodimeric protein complex that possesses 4-amino-4-deoxychorismate synthase activity. GO:0010345 suberin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010345 MetaCyc:PWY-1121 The chemical reactions and pathways resulting in the formation of suberin monomers and suberin polyesters. Suberin monomers are derived from fatty acids and trans-cinnamic acids. The monomers are then cross-linked with glycerols. GO:0034313 diol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034313 diol catabolism|dihydric alcohol catabolic process|diol degradation|diol breakdown The chemical reactions and pathways resulting in the breakdown of a diol, any alcohol containing two hydroxyl groups attached to saturated carbon atoms. GO:0009357 protein-N(PI)-phosphohistidine-sugar phosphotransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009357 An enzyme complex that catalyzes the transfer of a phosphate from protein N(PI)-phosphohistidine to a sugar molecule. It is enzyme II of the phosphotransferase system. GO:0010346 shoot axis formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010346 shoot formation The process that gives rise to a shoot axis. This process pertains to the initial formation of a structure from unspecified parts. CHEBI:139019 AZD1979 oxetane hydrolysis product biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139019 GO:0009358 polyphosphate kinase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009358 A protein complex that possesses polyphosphate kinase activity. GO:0034314 Arp2/3 complex-mediated actin nucleation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034314 branched actin filament nucleation|actin filament branch nucleation The actin nucleation process in which actin monomers combine to form a new branch on the side of an existing actin filament; mediated by the Arp2/3 protein complex and its interaction with other proteins. GO:0010343 singlet oxygen-mediated programmed cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010343 light-dependent programmed cell death|programmed cell death in response to singlet oxygen Programmed cell death induced by singlet oxygen. Programmed cell death is the cell death resulting from activation of endogenous cellular processes. CHEBI:62943 prostanoid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62943 GO:0009359 type II site-specific deoxyribonuclease complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009359 type II restriction enzyme complex A protein complex that functions as an endonuclease to cleave DNA at or near a specific recognition site, when that site is unmethylated. These complexes may be dimers or tetramers; it is also possible for the endonuclease to be in a complex with the corresponding methyltransferase that methylates the recognition site. DNA restriction systems such as this are used by bacteria to defend against phage and other foreign DNA that may enter a cell. GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034315 Any process that modulates the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins. CHEBI:62944 sialic acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62944 GO:0010344 seed oilbody biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010344 seed oil body organization|spherosome biogenesis|oleosome biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a seed oilbody. Seed oilbodies are simple organelles comprising a matrix of triglyceride surrounded by a phospholipid monolayer embedded and covered with unique proteins called oleosins. Seed oilbodies supply the energy requirements for the growth of the seedling after germination. GO:0034305 regulation of asexual sporulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034305 regulation of mitotic sporulation|regulation of asexual spore formation|regulation of mitotic spore formation Any process that modulates the frequency, rate or extent of spore formation from the products of mitosis. GO:0034306 regulation of sexual sporulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034306 regulation of sexual spore formation|regulation of meiotic sporulation|MAPKKK cascade during sporulation|regulation of meiotic spore formation Any process that modulates the frequency, rate or extent of spore formation from the products of meiosis. An example of this is found in Saccharomyces cerevisiae. GO:0010358 leaf shaping biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010358 leaf structural organization The developmental process that pertains to the organization of a leaf in three-dimensional space once the structure has initially formed. GO:0034307 regulation of ascospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034307 MAPKKK cascade during sporulation Any process that modulates the frequency, rate or extent of ascospore formation. An example of this process is found in Saccharomyces cerevisiae. GO:0010359 regulation of anion channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010359 Any process that modulates the frequency, rate or extent of anion channel activity. GO:0034308 primary alcohol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034308 primary alcohol metabolism|monohydric alcohol metabolic process The chemical reactions and pathways involving primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it. GO:0034309 primary alcohol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034309 primary alcohol anabolism|monohydric alcohol biosynthetic process|primary alcohol synthesis|primary alcohol formation|primary alcohol biosynthesis The chemical reactions and pathways resulting in the formation of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it. GO:0009370 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009370 GO:0009371 positive regulation of transcription by pheromones biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009371 upregulation of transcription by pheromones|up regulation of transcription by pheromones|activation of transcription by pheromones|stimulation of transcription by pheromones|up-regulation of transcription by pheromones Any process involving pheromones that activates or increases the rate of transcription. GO:0009372 quorum sensing biolink:BiologicalProcess go-plus goslim_pir|goslim_metagenomics http://purl.obolibrary.org/obo/GO_0009372 Wikipedia:Quorum_sensing cell-cell signaling involved in quorum sensing|detection of cell density by secreted molecule|quorum sensing system The cell-cell signaling process in which single-celled organisms carry out coordinated responses by monitoring their own population density, and often also that of other microbes, by producing small, diffusible, signal molecules, detecting the concentration of these molecules, and triggering a signal transduction pathway when a certain threshold is reached. Quorum sensing can occur amongst microbial communities in the environment or within host organisms. GO:0009373 regulation of transcription by pheromones biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009373 Any process involving pheromones that modulates the frequency, rate or extent of transcription. GO:0010352 lithium ion export across the plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010352 lithium ion efflux|lithium export|lithium ion export The directed movement of lithium ion out of a cell or organelle. GO:0010353 response to trehalose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010353 response to trehalose stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose stimulus. GO:0009364 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009364 GO:0009365 protein histidine kinase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009365 A complex that possesses protein histidine kinase activity. GO:0010350 cellular response to magnesium starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010350 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of magnesium. GO:0010351 lithium ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010351 lithium transport The directed movement of lithium ion into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0009366 enterobactin synthetase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009366 MetaCyc:ENTMULTI-CPLX enterochelin synthetase complex A multienzyme complex usually composed of four proteins, EntB, EntD, EntE and EntF. Plays a role in the enterobactin biosynthesis pathway. GO:0034300 sporangiospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034300 The process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm. GO:0034301 endospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034301 The process in which a cell gives rise to an endospore, a dormant, highly resistant spore with a thick wall that forms within the mother cell. Endospores are produced by some low G+C Gram-positive bacteria in response to harsh conditions. GO:0009367 obsolete prepilin peptidase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009367 prepilin peptidase complex OBSOLETE. An enzyme complex that catalyzes the cleavage of a Gly-Phe bond to release an N-terminal, basic peptide of 5-8 residues from type IV prepilin, and then N-methylates the new N-terminal amino group. GO:0010356 homogentisate geranylgeranyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010356 Catalysis of the reaction: homogentisic acid + geranylgeranyl diphosphate = 2-methyl-6-geranylgeranylplastoquinol. GO:0009368 endopeptidase Clp complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0009368 A protein complex comprised of members of the ClpX, ClpC, ClpD, ClpP or ClpR protein families. ClpPs are the proteolytic subunit of active complexes, and ClpA and ClpX form the regulatory subunits. Enzymatically active and inactive complexes can form. GO:0010357 homogentisate solanesyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010357 Catalysis of the reaction: homogentisic acid + all-trans-nonaprenyl diphosphate + 3 H+ = 2-methyl-6-solanyl-1,4-benzoquinonone + CO2 + diphosphate. 2-methyl-6-solanyl-1,4-benzoquinonone is also known as 2-methyl-6-solanesylplastoquinol and all-trans-nonaprenyl diphosphate as solanesyl diphosphate. GO:0034302 akinete formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034302 The process in which an akinete, a thick-walled (encysted) dormant cell derived from the enlargement of a vegetative cell, is formed. Akinetes typically have granular cytoplasm, are more resistant to environmental extremes than vegetative cells, and are characteristic of several groups of Cyanobacteria. GO:0009369 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009369 GO:0010354 homogentisate prenyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010354 Catalysis of the transfer of a prenyl group from one compound (donor) to homogentisic acid. GO:0034303 myxospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034303 The process in which differentiated, resting cells are formed, usually within a fruiting body by Myxobacteria. The myxospore is more resistant to high temperature, dessication, and UV than vegetative myxobacteria. GO:0010355 homogentisate farnesyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010355 Catalysis of the reaction: homogentisic acid + farnesyl diphosphate = 2-methyl-6-farnesylplastoquinol. GO:0034304 actinomycete-type spore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034304 The process in which differentiated, resting cells are formed from a substrate mycelium; characteristic of many members of the order Actinomycetales. CHEBI:139025 2-hydroxytetradecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139025 CHEBI:62958 N-acetyl-alpha-D-glucosaminyl-1-diphospho-ditrans,polycis-undecaprenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62958 CHEBI:62959 N-acetyl-alpha-D-glucosaminyl-1-diphospho-ditrans,polycis-undecaprenol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62959 CHEBI:139021 cis-alkene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139021 CHEBI:139022 2-hydroxyheptadecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139022 CHEBI:139023 2-hydroxyicosanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139023 CHEBI:139024 2-hydroxydodecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139024 GO:0010327 acetyl CoA:(Z)-3-hexen-1-ol acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010327 hexenol acetyltransferase Catalysis of the reaction: acetyl-CoA + (Z)-3-hexen-1-ol = CoA + (Z)-3-hexen-1-yl acetate. GO:0010328 auxin influx transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010328 auxin influx facilitator Enables the transfer of auxin, from one side of a membrane to the other, into a cell. GO:0010325 raffinose family oligosaccharide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010325 raffinose family oligosaccharide biosynthesis The chemical reactions and pathways resulting in the formation of raffinose family oligosaccharides (RFOs, such as raffinose, stachyose, verbascose and other molecules with a higher degree of galactosyl polymerization). GO:0010326 methionine-oxo-acid transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010326 MetaCyc:RXN-2201 Catalysis of the reaction: methionine + a 2-oxo acid = 2-oxo-4-methylthiobutanoate + an amino acid. UBERON:0014701 extraembryonic vascular system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014701 A vascular system that overlaps a umbilical cord and is part of a entire extraembryonic component. CHEBI:1729 4'-demethyldeoxypodophyllotoxin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_1729 GO:0010329 auxin efflux transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010329 auxin efflux carrier|auxin efflux facilitator Enables the transfer of auxin, from one side of a membrane to the other, out of a cell. GO:0009340 DNA topoisomerase IV complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009340 A heterodimeric enzyme, which in most bacterial species is composed of two subunits, ParC and ParE. Functions in chromosome segregation and can relax supercoiled DNA. GO:0009330 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009330 Complex that possesses DNA topoisomerase II (double strand cut, ATP-hydrolyzing) activity. GO:0009331 glycerol-3-phosphate dehydrogenase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009331 An enzyme complex that catalyzes the dehydrogenation of sn-glycerol 3-phosphate to form glycerone phosphate. GO:0010320 obsolete arginine/lysine endopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010320 arginine/lysine endopeptidase activity OBSOLETE. Catalysis of the hydrolysis of peptide linkages in oligopeptides or polypeptides by a reaction mechanism in which arginine or lysine residues act as nucleophiles. GO:0009332 glutamate-tRNA ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009332 An enzyme complex that catalyzes the ligation of glutamate and tRNA(Glu) to form glutamyl-tRNA(Glu). GO:0009333 cysteine synthase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009333 Cysteine synthase is a multienzyme complex made up, in E. coli, of the heteromeric hexamer serine acetyltransferase and the homodimer O-acetylserine (thiol)-lyase A. GO:0009334 3-phenylpropionate dioxygenase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009334 MetaCyc:HCAMULTI-CPLX Enzyme complex consisting of four proteins: the two subunits of the hydroxylase component (hcaE and hcaF), a ferredoxin (hcaC) and a ferredoxin reductase (hcaD). Converts 3-phenylpropionic acid (PP) into cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol). GO:0010323 negative regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010323 downregulation of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway|down regulation of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway|inhibition of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway|negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway|down-regulation of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of isopentenyl diphosphate produced via the methylerythritol (MEP) pathway (mevalonate-independent). GO:0010324 membrane invagination biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0010324 single-organism membrane invagination The infolding of a membrane. GO:0009335 obsolete holo-[acyl-carrier protein] synthase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009335 holo-[acyl-carrier protein] synthase complex|holo-ACP synthase complex OBSOLETE. An enzyme complex that catalyzes the formation of holo-[acyl-carrier protein] from CoA and apo-[acyl-carrier protein]. GO:0010321 regulation of vegetative phase change biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010321 Any process that modulates the frequency, rate or extent of vegetative phase change. Vegetative phase change is the set of post-embryonic processes involved in the transition of a plant from a juvenile phase of vegetative development to an adult phase of vegetative development. GO:0009336 sulfate adenylyltransferase complex (ATP) biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009336 sulphate adenylyltransferase complex (ATP) An enzyme complex that catalyzes the formation adenylylsulfate from sulfate and ATP. CHEBI:1722 3beta-hydroxy-Delta(5)-steroid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_1722 GO:0009337 sulfite reductase complex (NADPH) biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009337 sulphite reductase complex (NADPH) A multisubunit iron flavoprotein, which in yeast is composed of 2 alpha and 2 beta subunits. Catalyzes the reduction of sulfite to sulfide. GO:0010322 regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010322 regulation of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of isopentenyl diphosphate produced via the methylerythritol (MEP) pathway (mevalonate-independent). GO:0009338 exodeoxyribonuclease V complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009338 An enzyme complex that catalyzes exonucleolytic cleavage (in the presence of ATP) in either 5' to 3' or 3' to 5' direction to yield 5'-phosphooligonucleotides. Exodeoxyribonuclease V shows a preference for double-stranded DNA and possesses DNA-dependent ATPase activity. It acts endonucleolytically on single-stranded circular DNA. GO:0009339 glycolate oxidase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009339 An enzyme complex that catalyzes the oxidation of 2-hydroxy acid to form 2-oxo acid and hydrogen peroxide (H2O2). The enzyme is a flavoprotein (FMN). GO:0010338 leaf formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010338 The process that gives rise to a leaf. This process pertains to the initial formation of a structure from unspecified parts. GO:0010339 external side of cell wall biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0010339 The side of the cell wall that is opposite to the side that faces the cell and its contents. GO:0010336 gibberellic acid homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010336 gibberellin homeostasis Any biological process involved in the maintenance of an internal steady state of gibberellic acid; may involve transport, biosynthesis, catabolism or conjugation. GO:0010337 regulation of salicylic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010337 regulation of salicylic acid metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving salicylic acid. CHEBI:47395 devancoaminyl vancomycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47395 GO:0009350 ethanolamine ammonia-lyase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009350 An enzyme complex that catalyzes the breakdown of ethanolamine to form acetaldehyde and ammonia. GO:0009351 obsolete dihydrolipoamide S-acyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009351 dihydrolipoamide S-acyltransferase complex OBSOLETE. An enzyme complex that catalyzes the transfer of an acyl group from coenzyme A to dihydrolipoamide. GO:0010330 cellulose synthase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0010330 CESA complex A large, multimeric protein complex, organized in a rosette, which catalyzes the biosynthesis of cellulose for the plant cell wall. GO:0009341 beta-galactosidase complex biolink:CellularComponent go-plus goslim_metagenomics http://purl.obolibrary.org/obo/GO_0009341 A protein complex that possesses beta-galactosidase activity, i.e. catalyzes the hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides. In E. coli, the complex is a homotetramer; dimeric and hexameric beta-galactosidase complexes have been observed in other species. CHEBI:62974 cellotetraose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62974 GO:0009342 glutamate synthase complex (NADPH) biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009342 A complex that possesses glutamate synthase (NADPH) activity. GO:0010331 gibberellin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010331 gibberellic acid receptor|gibberellin receptor Interacting selectively and non-covalently with gibberellins, plant hormones that regulate aspects of plant growth. GO:0009343 biotin carboxylase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009343 An enzyme complex that catalyzes the formation of carboxybiotin-carboxyl-carrier protein from biotin-carboxyl-carrier protein and carbon dioxide (CO2). GO:0009344 nitrite reductase complex [NAD(P)H] biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009344 Complex that possesses nitrite reductase [NAD(P)H] activity. GO:0009345 glycine-tRNA ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009345 glycine-tRNA synthetase complex A multimeric enzyme complex which, in bacteria, is usually a tetramer of two alpha and two beta chains and in eukaryotes, is usually a homodimer. Functions in the ligation of glycine and tRNA(Gly) to form glycyl-tRNA(Gly). GO:0010334 sesquiterpene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010334 Catalysis of the reaction: trans,trans-farnesyl diphosphate = a sesquiterpene + diphosphate. Sesquiterpenes are terpenes containing three isoprene units, i.e. 15 carbons. CHEBI:62978 4-hydroxyprolinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62978 GO:0010335 response to non-ionic osmotic stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010335 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of non-ionic solutes (e.g. mannitol, sorbitol) in the environment. GO:0009346 citrate lyase complex biolink:CellularComponent go-plus goslim_metagenomics http://purl.obolibrary.org/obo/GO_0009346 Citrate lyase is a multienzyme complex with three constituents: the alpha subunit, citrate-ACP transferase; the beta subunit, citryl-ACP lyase; and the gamma subunit, an acyl-carrier protein which also carries the prosthetic group components. All three subunits are required for citrate lyase enzyme activity. CHEBI:62979 5-hydroxylysinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62979 GO:0010332 response to gamma radiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010332 response to gamma ray|response to gamma-ray photon Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum. CHEBI:62976 cellopentaose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62976 GO:0009347 aspartate carbamoyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009347 A multienzyme complex that catalyzes the formation N-carbamoyl-L-aspartate from carbamoyl phosphate and L-aspartate. It exhibits a variety of architectural organizations, but in all microorganisms the core catalytic component is a homotrimer of approximately 34 kDa polypeptides. GO:0010333 terpene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010333 Catalysis of the formation of cyclic terpenes through the cyclization of linear terpenes (e.g. isopentenyl-PP, geranyl-PP, farnesyl-PP and geranylgeranyl-PP) containing varying numbers of isoprene units. GO:0009348 ornithine carbamoyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009348 A homotrimeric protein complex that catalyzes the transfer of a carbamoyl group to ornithine, forming citrulline. GO:0009349 riboflavin synthase complex biolink:CellularComponent go-plus goslim_metagenomics http://purl.obolibrary.org/obo/GO_0009349 An flavoprotein that catalyzes the reaction the breakdown of dimethyl(ribityl)lumazine to form riboflavin and ribitylamino-amino-dihydroxypyrimidine. GO:0000982 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000982 GO:0000983 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000983 GO:0000984 bacterial-type RNA polymerase transcription regulatory region sequence-specific DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000984 eubacterial-type RNA polymerase regulatory region sequence-specific DNA binding|bacterial-type RNA polymerase regulatory region DNA binding|eubacterial-type RNA polymerase regulatory region DNA binding Interacting selectively and non-covalently with a sequence of DNA that is part of a regulatory region that controls the transcription of a gene or operon by a bacterial-type RNA polymerase. GO:0000985 bacterial-type RNA polymerase core promoter sequence-specific DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000985 eubacterial-type RNA polymerase core promoter sequence-specific DNA binding Interacting selectively and non-covalently with a DNA sequence that is part of the core promoter of a bacterial gene. GO:0000980 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000980 GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000981 transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding|transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding|sequence-specific distal enhancer binding RNA polymerase II transcription factor activity|sequence-specific DNA binding RNA polymerase II transcription factor activity|metal ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity|zinc ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II transcription factor activity, zinc ion regulated proximal promoter sequence-specific DNA binding|RNA polymerase II transcription factor activity, metal ion regulated sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|transcription factor|RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity|metal ion regulated sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II transcription factor activity, metal ion regulated proximal promoter sequence-specific DNA binding|copper ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity|sequence-specific transcription regulatory region DNA binding RNA polymerase II transcription factor recruiting transcription factor activity|RNA polymerase II transcription factor activity, metal ion regulated core promoter proximal region sequence-specific binding|RNA polymerase II transcription factor activity, zinc ion regulated core promoter proximal region sequence-specific DNA binding|RNA polymerase II transcription factor activity, copper ion regulated proximal promoter sequence-specific DNA binding|RNA polymerase II transcription factor activity, copper ion regulated core promoter proximal region sequence-specific binding|transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding|RNA polymerase II transcription factor activity, sequence-specific DNA binding A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II. GO:0010305 leaf vascular tissue pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010305 Vascular tissue pattern formation as it occurs in the leaf of vascular plants. GO:0010306 rhamnogalacturonan II biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010306 The chemical reactions and pathways resulting in the formation of rhamnogalacturonan II, a low molecular mass (5 - 10KDa) pectic polysaccharide, conserved in the primary walls of dicotyledenous and monocotyledenous plants and gymnosperms. GO:0010303 limit dextrinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010303 MetaCyc:3.2.1.142-RXN|MetaCyc:3.2.1.10-RXN|MetaCyc:RXN-1824|EC:3.2.1.142 amylopectin-1,6-glucosidase activity|dextrin alpha-1,6-glucanohydrolase activity|R-enzyme Catalysis of the hydrolysis of (1,6)-alpha-D-glucosidic linkages in alpha- and beta-limit dextrins of amylopectin and glycogen, and in amylopectin and pullulan. GO:0010304 PSII associated light-harvesting complex II catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010304 LHCII catabolism The chemical reactions and pathways resulting in the breakdown of one or more components of the light-harvesting complex of photosystem II. GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010309 KEGG_REACTION:R07364|EC:1.13.11.54|Reactome:R-HSA-1237119|RHEA:24504|MetaCyc:R147-RXN 2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase|acireductone dioxygenase activity|1,2-dihydroxy-5-(methylthio)pent-1-en-3-one:oxygen oxidoreductase (formate-forming)|ARD1|E-2'|1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase activity|acireductone dioxygenase (Fe2+-requiring) activity|ARD'|aci-reductone dioxygenase Catalysis of the reaction: 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O(2) = 4-methylthio-2-oxobutanoate + formate + H(+). CHEBI:62981 4-hydroxy-L-prolinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62981 OBA:0100001 cellular component attribute biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0100001 quality of cellular_component The quality of a cellular_component. GO:0010307 acetylglutamate kinase regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010307 Modulates the enzyme activity of acetylglutamate kinase. GO:0010308 acireductone dioxygenase (Ni2+-requiring) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010308 KEGG_REACTION:R07363|RHEA:14161|EC:1.13.11.53|MetaCyc:R146-RXN 2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase activity|acireductone dioxygenase activity|E-2 activity|1,2-dihydroxy-5-(methylthio)pent-1-en-3-one:oxygen oxidoreductase (formate- and CO-forming)|ARD activity Catalysis of the reaction: 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O(2) = 3-(methylthio)propanoate + CO + formate. CHEBI:62980 homoserinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62980 OBA:0100004 chemical entity attribute biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0100004 quality of chemical entity The quality of a chemical entity. OBA:0100005 protein attribute biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0100005 quality of protein The quality of a protein. OBA:0100002 biological process attribute biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0100002 quality of biological_process The quality of a biological_process. GO:0009310 amine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009310 amine catabolism|amine degradation|amine breakdown The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. OBA:0100003 anatomical entity attribute biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0100003 quality of anatomical entity The quality of a anatomical entity. GO:0009311 oligosaccharide metabolic process biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0009311 oligosaccharide metabolism|multicellular organismal oligosaccharide metabolic process The chemical reactions and pathways involving oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages. GO:0010301 xanthoxin dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010301 MetaCyc:1.1.1.288-RXN|EC:1.1.1.288|RHEA:12548|KEGG_REACTION:R06954 ABA2|xanthoxin:NAD+ oxidoreductase activity|xanthoxin oxidase activity Catalysis of the reaction: NAD(+) + xanthoxin = (+)-abscisic aldehyde + H(+) + NADH. GO:0009312 oligosaccharide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009312 oligosaccharide anabolism|oligosaccharide synthesis|oligosaccharide formation|oligosaccharide biosynthesis The chemical reactions and pathways resulting in the formation of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages. CHEBI:62989 chenodeoxycholoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62989 GO:0010302 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010302 GO:0009313 oligosaccharide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009313 oligosaccharide catabolism|oligosaccharide degradation|oligosaccharide breakdown|multicellular organismal oligosaccharide catabolic process The chemical reactions and pathways resulting in the breakdown of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages. GO:0009314 response to radiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009314 response to radiation stimulus|response to electromagnetic radiation stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation. GO:0010300 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010300 GO:0009315 obsolete drug resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009315 drug resistance OBSOLETE. (Was not defined before being made obsolete). GO:0009316 3-isopropylmalate dehydratase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009316 MetaCyc:3-ISOPROPYLMALISOM-CPLX isopropylmalate isomerase complex A heterodimeric enzyme complex composed of subunits leuC and leuD. Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate. GO:0009317 acetyl-CoA carboxylase complex biolink:CellularComponent go-plus goslim_pir|goslim_metagenomics http://purl.obolibrary.org/obo/GO_0009317 ACCase complex A protein complex that catalyzes the first step in long-chain fatty acid biosynthesis. For example, in E. coli the complex is heterohexameric and composed of biotin carbonyl carrier protein, biotin carboxylase and the acetate CoA-transferase complex. GO:0009318 exodeoxyribonuclease VII complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009318 An enzyme complex that catalyzes exonucleolytic cleavage in either 5' to 3' or 3' to 5' direction to yield nucleoside 5'-phosphates; it prefers single-stranded DNA. GO:0009319 cytochrome o ubiquinol oxidase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009319 MetaCyc:CYT-O-UBIOX-CPLX A protein complex that possesses cytochrome o ubiquinol oxidase activity; consists of four polypeptide subunits and associated prosthetic groups. GO:0000986 bacterial-type cis-regulatory region sequence-specific DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000986 bacterial-type RNA polymerase enhancer sequence-specific DNA binding|bacterial-type proximal promoter sequence-specific DNA binding|bacterial-type RNA polymerase upstream activating sequence (UAS) sequence-specific DNA binding|eubacterial-type RNA polymerase regulatory transcription factor sequence-specific DNA binding|bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding Interacting selectively and non-covalently with a specific upstream cis-regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the promoter of a bacterial gene (or cistron, or operon). GO:0000987 cis-regulatory region sequence-specific DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000987 core promoter proximal region DNA binding|core promoter proximal region sequence-specific DNA binding|promoter proximal region sequence-specific DNA binding|enhancer binding|cis-regulatory region binding|enhancer sequence-specific DNA binding|proximal promoter sequence-specific DNA binding Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by some RNA polymerase. The proximal promoter is in cis with and relatively close to the core promoter. GO:0000988 obsolete transcription factor activity, protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000988 transcription factor activity|protein binding transcription factor activity OBSOLETE. Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. GO:0000989 obsolete transcription factor activity, transcription factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000989 transcription factor binding transcription factor activity OBSOLETE. Interacting selectively and non-covalently with a specific transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. GO:0000993 RNA polymerase II complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000993 RNAP II core binding|RNA polymerase II core binding Interacting selectively and non-covalently with RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits. GO:0000994 RNA polymerase III core binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000994 Interacting selectively and non-covalently with RNA polymerase III core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of seventeen subunits. GO:0000995 RNA polymerase III general transcription initiation factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000995 RNA polymerase III transcription factor activity, sequence-specific DNA binding|transcription factor activity, core RNA polymerase III binding|RNA polymerase III general initiation factor activity|sequence-specific DNA binding RNA polymerase III transcription factor activity|core RNA polymerase III binding transcription factor activity A general transcription initiation factor activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase III. Factors required for RNA polymerase III transcription initiation include TFIIIA, TFIIIB and TFIIIC. A general transcription initiation factor activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase III. Factors required for RNA polymerase III transcription initiation include TFIIIA, TFIIIB and TFIIIC. RNA polymerase III transcribes genes encoding short RNAs, including tRNAs, 5S rRNA, U6 snRNA, the short ncRNA component of RNases P, the mitochondrial RNA processing (MRP) RNA, the signal recognition particle SRP RNA, and in higher eukaryotes a number of micro and other small RNAs, though there is some variability across species as to whether a given small noncoding RNA is transcribed by RNA polymerase II or RNA polymerase III. GO:0000996 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000996 GO:0000990 obsolete transcription factor activity, core RNA polymerase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000990 core RNA polymerase binding transcription factor activity OBSOLETE. Interacting selectively and non-covalently with an RNA polymerase in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. CHEBI:72316 virulence factor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72316 GO:0000991 obsolete transcription factor activity, core RNA polymerase II binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000991 core RNA polymerase II binding transcription factor activity OBSOLETE. Interacting selectively and non-covalently with an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. GO:0000992 RNA polymerase III cis-regulatory region sequence-specific DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000992 Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase III. The transcribed region might be contain a single gene or a cistron containing multiple genes. GO:0010316 pyrophosphate-dependent phosphofructokinase complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0010316 PFK complex Heterodimeric complex that catalyzes the pyrophosphate-dependent phosphorylation of D-fructose 6-phosphate into D-fructose 1,6-bisphosphate. GO:0010317 pyrophosphate-dependent phosphofructokinase complex, alpha-subunit complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0010317 PFK complex, alpha-subunit Refers to the alpha subunit of the heterodimeric complex that possesses pyrophosphate-dependent phosphofructokinase activity. GO:0010314 phosphatidylinositol-5-phosphate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010314 Interacting selectively and non-covalently with phosphatidylinositol-5-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 5' position. GO:0010315 auxin efflux biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010315 auxin export The process involved in the transport of auxin out of the cell. GO:0010318 pyrophosphate-dependent phosphofructokinase complex, beta-subunit complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0010318 PFK complex, beta-subunit Refers to the beta subunit of the heterodimeric complex that possesses pyrophosphate-dependent phosphofructokinase activity. GO:0010319 stromule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0010319 Wikipedia:Stromule Stroma-filled tubule Thin filamentous structure extending from the surface of all plastid types examined so far, including chloroplast, proplastid, etioplast, leucoplast, amyloplast, and chromoplast. In general, stromules are more abundant in tissues containing non-green plastids, and in cells containing smaller plastids. The primary function of stromules is still unresolved, although the presence of stromules markedly increases the plastid surface area, potentially increasing transport to and from the cytosol. Other functions of stromules, such as transfer of macromolecules between plastids and starch granule formation in cereal endosperm, may be restricted to particular tissues and cell types. GO:0009320 phosphoribosylaminoimidazole carboxylase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009320 A protein complex that possesses phosphoribosylaminoimidazole carboxylase activity. GO:0009321 alkyl hydroperoxide reductase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009321 An enzyme complex, usually a homodimer, which directly reduces cellular levels of organic hydroperoxides. GO:0009322 trimethylamine-N-oxide reductase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009322 An enzyme complex that catalyzes the reduction of trimethylamine N-oxide to trimethylamine. GO:0010312 detoxification of zinc ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010312 Any process that reduces or removes the toxicity of zinc ion. These include transport of zinc away from sensitive areas and to compartments or complexes whose purpose is sequestration of zinc ion. GO:0009323 ribosomal-protein-alanine N-acetyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009323 RHEA:43752|EC:2.3.1.128 An enzyme complex that catalyzes the transfer of an acetyl group to ribosomal-protein alanine, forming ribosomal-protein acetylalanine. GO:0009324 D-amino-acid dehydrogenase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009324 A protein complex that possesses D-amino-acid dehydrogenase activity. GO:0010313 phytochrome binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010313 Interacting selectively and non-covalently with phytochrome. GO:0010310 regulation of hydrogen peroxide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010310 regulation of hydrogen peroxide metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide. GO:0009325 nitrate reductase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009325 An enzyme complex that catalyzes the formation of nitrate from nitrite with the concomitant reduction of an acceptor. GO:0010311 lateral root formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010311 lateral root primordium development The process that gives rise to a lateral root. This process pertains to the initial formation of a structure from unspecified parts. A lateral root primordium represents an organized group of cells derived from the root pericycle that will differentiate into a new root, as opposed to the initiation of the main root from the embryo proper. GO:0009326 formate dehydrogenase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009326 EC:1.17.1.9 An enzyme complex that catalyzes the dehydrogenation of formate to produce carbon dioxide (CO2). GO:0009327 NAD(P)+ transhydrogenase complex (AB-specific) biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009327 A protein complex that possesses NAD(P)+ transhydrogenase (AB-specific) activity. Homodimeric, trimeric, and heterotetrameric complexes have been identified. GO:0009328 phenylalanine-tRNA ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009328 An enzyme complex that catalyzes the ligation of phenylalanine to tRNA(Phe), forming L-phenylalanyl-tRNA(Phe). GO:0009329 acetate CoA-transferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009329 A heterotetrameric enzyme complex made up of two alpha subunits and two beta subunits. Part of the acetyl-CoA carboxylase complex. Catalyzes the transfer of a carboxyl group to form malonyl-CoA. GO:0000997 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000997 GO:0000998 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000998 GO:0000999 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000999 GO:1902779 cellular response to alkane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902779 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkane stimulus. GO:1902777 6-sulfoquinovose(1-) catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902777 6-sulfoquinovose(1-) degradation|6-sulfoquinovose(1-) breakdown|6-sulfoquinovose(1-) catabolism The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-). GO:1902778 response to alkane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902778 process resulting in tolerance to alkane Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkane stimulus. GO:1902775 mitochondrial large ribosomal subunit assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902775 39S ribosomal subunit, mitochondrial formation|39S ribosomal subunit, mitochondrial assembly|mitochondrial large ribosomal subunit formation The aggregation, arrangement and bonding together of a set of components to form a mitochondrial large ribosomal subunit. GO:1902776 6-sulfoquinovose(1-) metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902776 6-sulfoquinovose(1-) metabolism The chemical reactions and pathways involving 6-sulfoquinovose(1-). GO:1902773 GTPase activator complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902773 A protein complex which is capable of GTPase activator activity. GO:1902774 late endosome to lysosome transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902774 prevacuolar compartment to lysosome transport The directed movement of substances from late endosome to lysosome. GO:1902771 positive regulation of choline O-acetyltransferase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902771 positive regulation of choline acetyltransferase activity|up-regulation of choline acetylase activity|activation of choline acetylase activity|up regulation of choline acetyltransferase activity|up regulation of choline O-acetyltransferase activity|up regulation of acetyl-CoA:choline O-acetyltransferase activity|activation of acetyl-CoA:choline O-acetyltransferase activity|positive regulation of acetyl-CoA:choline O-acetyltransferase activity|positive regulation of CHOACTase activity|up regulation of CHOACTase activity|positive regulation of choline acetylase activity|upregulation of choline acetyltransferase activity|up regulation of choline acetylase activity|upregulation of choline O-acetyltransferase activity|up-regulation of acetyl-CoA:choline O-acetyltransferase activity|up-regulation of choline acetyltransferase activity|upregulation of CHOACTase activity|activation of choline acetyltransferase activity|activation of choline O-acetyltransferase activity|upregulation of choline acetylase activity|up-regulation of choline O-acetyltransferase activity|upregulation of acetyl-CoA:choline O-acetyltransferase activity|up-regulation of CHOACTase activity|activation of CHOACTase activity Any process that activates or increases the frequency, rate or extent of choline O-acetyltransferase activity. GO:1902772 positive regulation of phosphorelay signal transduction system involved in hydrogen peroxide mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902772 up-regulation of two-component signal transduction involved in hydrogen peroxide mediated signalling pathway|upregulation of two-component signal transduction involved in H2O2 mediated signaling pathway|stimulation of two-component signal transduction involved in hydrogen peroxide mediated signaling pathway|up-regulation of two-component signal transduction involved in hydrogen peroxide mediated signaling pathway|positive regulation of phosphorelay signal transduction system involved in hydrogen peroxide mediated signalling pathway|activation of two-component signal transduction involved in hydrogen peroxide mediated signaling pathway|positive regulation of two-component signal transduction system (phosphorelay) involved in hydrogen peroxide mediated signaling pathway|positive regulation of histidyl-aspartyl phosphorelay involved in H2O2 mediated signaling pathway|upregulation of two-component signal transduction involved in hydrogen peroxide mediated signalling pathway|up regulation of two-component signal transduction involved in H2O2 mediated signaling pathway|positive regulation of two-component signal transduction system (phosphorelay) involved in H2O2 mediated signaling pathway|activation of two-component signal transduction involved in H2O2 mediated signaling pathway|stimulation of two-component signal transduction involved in H2O2 mediated signaling pathway|up regulation of two-component signal transduction involved in hydrogen peroxide mediated signaling pathway|positive regulation of histidyl-aspartyl phosphorelay involved in hydrogen peroxide mediated signalling pathway|positive regulation of histidyl-aspartyl phosphorelay involved in hydrogen peroxide mediated signaling pathway|up regulation of two-component signal transduction involved in hydrogen peroxide mediated signalling pathway|positive regulation of two-component signal transduction system (phosphorelay) involved in hydrogen peroxide mediated signalling pathway|activation of two-component signal transduction involved in hydrogen peroxide mediated signalling pathway|up-regulation of two-component signal transduction involved in H2O2 mediated signaling pathway|stimulation of two-component signal transduction involved in hydrogen peroxide mediated signalling pathway|upregulation of two-component signal transduction involved in hydrogen peroxide mediated signaling pathway|positive regulation of phosphorelay signal transduction system involved in H2O2 mediated signaling pathway Any positive regulation of phosphorelay signal transduction system that is involved in hydrogen peroxide mediated signaling pathway. GO:0034297 oidium formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034297 The process in which oidia, a type of asexual spore found in fungi, are formed. Oidia are borne a few at a time on very simple hyphae that protrude a short distance into the substrate, and are usually presumed not to constitute the main reproductive strategy of the fungus. GO:1902780 response to nonane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902780 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonane stimulus. GO:1902781 cellular response to nonane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902781 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonane stimulus. GO:0034298 arthrospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034298 arthroconidium formation The formation of conidia by the conversion of a pre-existing hypha. An arthrospore is produced by the last cell on a hypha breaking off and dispersing. Usually the walls thicken and the cell(s) separates before swelling of each spore. Sometimes further septa form in each cell prior to disarticulation. GO:0034299 reproductive blastospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034299 blastoconidium formation The formation of a spore following the marked enlargement of part of a cell before separation by a septum. Blastospores are a type of asexual spore found in some fungi, most notably the class Glomeromycota. GO:0034290 holin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034290 A compound function consisting of the regulated formation of a pore via oligomerisation of an existing pool of subunits in the plasma membrane. The resulting channel activity directly or indirectly allows murein hydrolyases to access their cell wall substrate. GO:0034291 canonical holin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034291 A compound function consisting of the regulated formation of a pore via oligomerisation of an existing pool of subunits in the plasma membrane. The resulting channel activity directly allows release of a fully-folded phage-encoded endolysin (murein-degradase) from the cell. GO:0034292 pinholin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034292 A compound function consisting of the regulated formation of a pore via oligomerisation of an existing pool of subunits in the plasma membrane. The resulting ion channel activity indirectly allows endolysin (murein hydrolyases) to access their cell wall substrate by collapsing the proton motive force (PMF) across the membrane, allowing the endolysin to fold to an active form and hydrolyze bonds in the peptidoglycan cell wall. GO:0034293 sexual sporulation biolink:BiologicalProcess go-plus goslim_aspergillus http://purl.obolibrary.org/obo/GO_0034293 meiotic spore formation|sexual spore formation|meiotic sporulation The formation of spores derived from the products of meiosis. GO:0034294 sexual spore wall assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034294 sexual spore wall formation The aggregation, arrangement and bonding together of a set of components to form a sexual spore wall, the specialized envelope lying outside the cell membrane of a spore derived from a product of meiosis. GO:0034295 basidiospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034295 The process in which spores form outside a specialized end cell known as a basidium. Basidia are characteristic of the basidiomycete fungi (phylum Basidiomycota), and give rise to spores that each contain a haploid nucleus that is the product of meiosis. The spores are usually attached to the basidium by short spikes called sterigmata (singular: sterigma). In most basidiomycetes there are four sterigmata (and four spores) to a basidium. GO:0034296 zygospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034296 The process in which zygospores are formed. Zygospores are characteristic of the zygomycete fungi (phylum Zygomycota) thick-walled and darkly colored, and usually heavily ornamented as well, with many spines or ridges. It is formed between two specialized organs called suspensors, which are themselves usually heavily ornamented, one from each mating partner. The zygospore forms between them and then breaks away. GO:1902788 response to isooctane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902788 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isooctane stimulus. GO:1902789 cellular response to isooctane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902789 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isooctane stimulus. GO:1902786 response to dodecane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902786 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dodecane stimulus. GO:1902787 cellular response to dodecane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902787 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dodecane stimulus. GO:1902784 response to undecane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902784 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an undecane stimulus. GO:1902785 cellular response to undecane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902785 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an undecane stimulus. GO:1902782 response to decane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902782 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a decane stimulus. GO:1902783 cellular response to decane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902783 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a decane stimulus. GO:0034286 response to maltose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034286 response to maltose stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a maltose stimulus. GO:1902791 undecan-2-one biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902791 undecan-2-one biosynthesis|undecan-2-one anabolism|undecan-2-one synthesis|undecan-2-one formation The chemical reactions and pathways resulting in the formation of undecan-2-one. GO:1902792 pyrroline-5-carboxylate reductase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902792 A protein complex which is capable of pyrroline-5-carboxylate reductase activity. GO:0034287 detection of monosaccharide stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034287 perception of monosaccharide stimulus The series of events in which a stimulus from a monosaccharide is received and converted into a molecular signal. GO:0034288 detection of disaccharide stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034288 perception of disaccharide stimulus The series of events in which a stimulus from a disaccharide is received and converted into a molecular signal. GO:1902790 undecan-2-one metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902790 undecan-2-one metabolism The chemical reactions and pathways involving undecan-2-one. GO:0034289 detection of maltose stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034289 perception of maltose stimulus The series of events in which a maltose stimulus is received by a cell and converted into a molecular signal. CHEBI:1774 (E)-4-(trimethylammonio)but-2-enoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_1774 GO:0034280 ent-sandaracopimaradiene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034280 MetaCyc:RXN-4884|EC:4.2.3.29|RHEA:25536|KEGG_REACTION:R09120 ent-copalyl-diphosphate diphosphate-lyase [ent-sandaracopimara-8(14),15-diene-forming] activity|ent-pimaradiene synthase activity Catalysis of the reaction: ent-copalyl diphosphate = ent-sandaracopimara-8(14),15-diene + diphosphate. GO:0034281 ent-isokaurene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034281 Catalysis of the reaction: ent-copalyl diphosphate = ent-isokaurene + diphosphate. GO:0034282 ent-pimara-8(14),15-diene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034282 MetaCyc:RXN-7788|EC:4.2.3.30|RHEA:25540|KEGG_REACTION:R09121 ent-copalyl-diphosphate diphosphate-lyase [ent-pimara-8(14),15-diene-forming] activity|ent-pimaradiene synthase activity Catalysis of the reaction: ent-copalyl diphosphate = ent-pimara-8(14),15-diene + diphosphate. GO:0034283 syn-stemod-13(17)-ene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034283 EC:4.2.3.34|RHEA:25556|MetaCyc:RXN-9291|KEGG_REACTION:R09116 stemodene synthase activity|stemod-13(17)-ene synthase activity|syn-stemodene synthase activity|9alpha-copalyl-diphosphate diphosphate-lyase [stemod-13(17)-ene-forming] activity|exo-stemodene synthase activity Catalysis of the reaction: 9-alpha-copalyl diphosphate = stemod-13(17)-ene + diphosphate. GO:0034284 response to monosaccharide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034284 response to monosaccharide stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus. GO:0034285 response to disaccharide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034285 response to disaccharide stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disaccharide stimulus. GO:1902799 regulation of phosphodiesterase I activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902799 regulation of PDE I activity|regulation of 5'NPDE activity|regulation of alkaline phosphodiesterase activity|regulation of 5'-PDE activity|regulation of exonuclease I activity|regulation of 5'-exonuclease activity|regulation of orthophosphoric diester phosphohydrolase activity|regulation of phosphodiesterase activity|regulation of 5'-PDase activity|regulation of 5'-phosphodiesterase activity|regulation of 5'-nucleotide phosphodiesterase activity|regulation of 5'-NPDase activity|regulation of 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity|regulation of nucleotide pyrophosphatase/phosphodiesterase I activity|regulation of oligonucleate 5'-nucleotidohydrolase activity Any process that modulates the frequency, rate or extent of phosphodiesterase I activity. GO:1902797 negative regulation of snoRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902797 down-regulation of snoRNA processing|inhibition of snoRNA processing|down regulation of snoRNA processing|downregulation of snoRNA processing Any process that stops, prevents or reduces the frequency, rate or extent of snoRNA processing. GO:1902798 positive regulation of snoRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902798 up-regulation of snoRNA processing|upregulation of snoRNA processing|up regulation of snoRNA processing|activation of snoRNA processing Any process that activates or increases the frequency, rate or extent of snoRNA processing. GO:1902795 heterochromatin domain assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902795 heterochromatin domain formation|HOOD formation|HOOD assembly The aggregation, arrangement and bonding together of a set of components to form a heterochromatin domain. GO:1902796 regulation of snoRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902796 Any process that modulates the frequency, rate or extent of snoRNA processing. GO:1902793 glutamate decarboxylase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902793 A protein complex which is capable of glutamate decarboxylase activity. GO:1902794 heterochromatin island assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902794 heterochromatin island formation The aggregation, arrangement and bonding together of a set of components to form a heterochromatin island. GO:0034275 kynurenic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034275 kynurenic acid metabolism|4-hydroxyquinoline-2-carboxylic acid metabolic process The chemical reactions and pathways involving kynurenic acid, 4-hydroxyquinoline-2-carboxylic acid. GO:0034276 kynurenic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034276 kynurenic acid synthesis|kynurenic acid biosynthesis|kynurenic acid formation|4-hydroxyquinoline-2-carboxylic acid biosynthetic process|kynurenic acid anabolism The chemical reactions and pathways resulting in the formation of kynurenic acid, 4-hydroxyquinoline-2-carboxylic acid. GO:0034277 ent-cassa-12,15-diene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034277 KEGG_REACTION:R09119|RHEA:25532|MetaCyc:RXN-4881|EC:4.2.3.28 ent-copalyl-diphosphate diphosphate-lyase (ent-cassa-12,15-diene-forming) activity Catalysis of the reaction: ent-copalyl diphosphate = ent-cassa-12,15-diene + diphosphate. GO:0034278 stemar-13-ene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034278 EC:4.2.3.33|RHEA:25552|KEGG_REACTION:R09115|MetaCyc:RXN-4882 9alpha-copalyl-diphosphate diphosphate-lyase (stemar-13-ene-forming) activity Catalysis of the reaction: 9-alpha-copalyl diphosphate = stemar-13-ene + diphosphate. GO:0034279 syn-pimara-7,15-diene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034279 EC:4.2.3.35|KEGG_REACTION:R09117|RHEA:25560|MetaCyc:RXN-4883 9alpha-copalyl-diphosphate diphosphate-lyase (9beta-pimara-7,15-diene-forming) activity Catalysis of the reaction: 9-alpha-copalyl diphosphate = 9-beta-pimara-7,15-diene + diphosphate. GO:0034270 Cvt complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034270 cytoplasm to vacuole targeting complex|cytoplasm-to-vacuole targeting complex A protein complex that is involved in the Cvt pathway. In budding yeast, the Cvt complex consists of multimers of preApe1p. GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034271 phosphatidylinositol 3-kinase complex I|autophagy-specific phosphatidylinositol 3-kinase (PtdIns3K) complex|PtdIns-3-kinase complex I A class III phosphatidylinositol 3-kinase complex that is involved in autophagy. In budding yeast, this complex consists of Vps30p, Vps34p, Apg14p and Vps15p. CHEBI:139098 alpha-D-galactosyl-(1->4)-beta-D-galactosyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139098 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type II biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034272 PtdIns-3-kinase complex II|phosphatidylinositol 3-kinase complex II A class III phosphatidylinositol 3-kinase complex that is involved in vacuolar protein sorting (VPS) via endosomes. In budding yeast, this complex consists of Vps30p, Vps34p, Vps38 and Vps15p. GO:0034273 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0034273 GO:0034274 Atg12-Atg5-Atg16 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034274 A protein complex required for the expansion of the autophagosomal membrane. In budding yeast, this complex consists of Atg12p, Atg5p and Atg16p. CHEBI:140083 O(3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl]-L-threonine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140083 CHEBI:140084 all-trans-retinyl octanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140084 CHEBI:140082 2-octanoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140082 CHEBI:140080 O(3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl]-L-serine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140080 CHEBI:140089 all-trans-retinyl dodecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140089 CHEBI:140087 O(3)-{N-acetyl-beta-D-glucosaminyl-(1->2)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-alpha-D-mannosyl}-L-threonine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140087 CHEBI:140088 2-dodecanoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140088 CHEBI:140085 O(3)-{N-acetyl-beta-D-glucosaminyl-(1->2)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-alpha-D-mannosyl}-L-serine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140085 CHEBI:140086 6,7-dichloro-L-tryptophan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_140086 GO:0034264 isopentenyl adenine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034264 isopentenyladenine metabolic process|isopentenyl adenine metabolism The chemical reactions and pathways involving the cytokinin 6-isopentenyladenine. GO:0034265 isopentenyl adenine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034265 isopentenyl adenine formation|isopentenyl adenine biosynthesis|isopentenyladenine biosynthetic process|isopentenyl adenine anabolism|isopentenyl adenine synthesis The chemical reactions and pathways resulting in the formation of the cytokinin 6-isopentenyladenine. GO:0034266 isopentenyl adenine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034266 isopentenyl adenine catabolism|isopentenyl adenine degradation|isopentenyladenine catabolic process|isopentenyl adenine breakdown The chemical reactions and pathways resulting in the breakdown of the cytokinin 6-isopentenyladenine. GO:0034267 discadenine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034267 discadenine metabolism The chemical reactions and pathways involving discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid. GO:0034268 discadenine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034268 discadenine anabolism|discadenine synthesis|discadenine formation|discadenine biosynthesis The chemical reactions and pathways resulting in the formation of discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid. GO:0034269 discadenine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034269 discadenine degradation|discadenine breakdown|discadenine catabolism The chemical reactions and pathways resulting in the breakdown of discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid. GO:0034260 negative regulation of GTPase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034260 down-regulation of Rho GTPase activity|negative regulation of Rho GTPase activity|downregulation of Rab GTPase activity|inhibition of Ras GTPase activity|inhibition of GTPase activity|negative regulation of Rab GTPase activity|inhibition of regulation of Ran GTPase activity|down regulation of Ras GTPase activity|down-regulation of Rab GTPase activity|inhibition of Rho GTPase activity|downregulation of Ras GTPase activity|down regulation of regulation of Ran GTPase activity|down regulation of GTPase activity|downregulation of regulation of Ran GTPase activity|down regulation of Rho GTPase activity|negative regulation of guanosinetriphosphatase activity|down-regulation of Ras GTPase activity|inhibition of Rab GTPase activity|downregulation of GTPase activity|negative regulation of Ras GTPase activity|downregulation of Rho GTPase activity|negative regulation of Ran GTPase activity|down-regulation of regulation of Ran GTPase activity|down regulation of Rab GTPase activity|down-regulation of GTPase activity Any process that stops or reduces the rate of GTP hydrolysis by a GTPase. GO:0034261 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0034261 GO:0034262 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0034262 GO:0034263 positive regulation of autophagy in response to ER overload biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034263 autophagy in response to ER stress|autophagy in response to endoplasmic reticulum overload The process in which the accumulation of misfolded proteins in the endoplasmic reticulum triggers a response that positively regulates autophagy. CHEBI:139083 (E)-hex-4-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139083 CHEBI:139085 (9R,13R)-1a,1b-dinor-10,11-dihydro-12-oxo-15-phytoenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139085 CHEBI:140077 6-chloro-L-tryptophan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_140077 GO:0009297 pilus assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009297 fimbria biogenesis|fimbriae biogenesis|fimbrium assembly|pilus biosynthesis|fimbria assembly|fimbriae assembly|pili biosynthetic process|pili biosynthesis|fimbrium biogenesis|fimbrial assembly|pilus formation|fimbrial biogenesis|pilus biogenesis The assembly of a pilus, a short filamentous structure on a bacterial cell, flagella-like in structure and generally present in many copies. Pili are variously involved in transfer of nucleic acids, adherence to surfaces, and formation of pellicles. Is required for bacterial conjugation, or can play a role in adherence to surfaces (when it is called a fimbrium), and in the formation of pellicles. GO:0034253 positive regulation of cellular amide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034253 positive regulation of amide catabolism|positive regulation of amide breakdown|positive regulation of amide degradation Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides. GO:0010286 heat acclimation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010286 thermotolerance Any process that increases heat tolerance of an organism in response to high temperatures. GO:0009298 GDP-mannose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009298 GDP-mannose synthesis|GDP-mannose formation|GDP-mannose biosynthesis|GDP-mannose anabolism The chemical reactions and pathways resulting in the formation of GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate. GO:0010287 plastoglobule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0010287 PG|plastoglobuli A lipoprotein particle present in chloroplasts. They are rich in non-polar lipids (triglycerides, esters) as well as in prenylquinones, plastoquinone and tocopherols. Plastoglobules are often associated with thylakoid membranes, suggesting an exchange of lipids with thylakoids. GO:0034254 regulation of urea catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034254 regulation of urea degradation|regulation of urea breakdown|regulation of urea catabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of urea. GO:0009299 mRNA transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009299 mRNA biosynthetic process|mRNA biosynthesis|mRNA synthesis|cellular mRNA transcription The cellular synthesis of messenger RNA (mRNA) from a DNA template. GO:0010284 lariciresinol reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010284 MetaCyc:RXN-8679|MetaCyc:RXN-8684 Catalysis of the reaction: lariciresinol + NADPH + H+ = secoisolariciresinol + NADP+. GO:0034255 regulation of urea metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034255 regulation of urea metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving urea. GO:0034256 chlorophyll(ide) b reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034256 EC:1.1.1.294|MetaCyc:RXN-7678 chlorophyll b reductase activity|Chl b reductase activity|chlorophyllide b reductase activity Catalysis of the reaction: 71-hydroxychlorophyll(ide) a + NAD(P)+ = chlorophyll(ide) b + NAD(P)H + H+. GO:0010285 L,L-diaminopimelate aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010285 MetaCyc:RXN-7737|RHEA:23988|KEGG_REACTION:R07613|EC:2.6.1.83 LL-diaminopimelate transaminase activity|LL-DAP-AT activity|LL-DAP aminotransferase activity|LL-2,6-diaminoheptanedioate:2-oxoglutarate aminotransferase activity|LL-diaminopimelate aminotransferase activity Catalysis of the reaction: 2-oxoglutarate + LL-2,6-diaminopimelate = (S)-2,3,4,5-tetrahydrodipicolinate + L-glutamate + H(2)O + H(+). GO:0034257 nicotinamide riboside transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034257 RHEA:33163 Enables the transfer of nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, from one side of a membrane to the other. GO:0034258 nicotinamide riboside transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034258 The directed movement of a nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0034259 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0034259 GO:0010288 response to lead ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010288 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus. GO:0010289 homogalacturonan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010289 MetaCyc:PWY-1061 The chemical reactions and pathways resulting in the formation of the pectidic homogalacturonan, characterized by a backbone of (1->4)-linked alpha-D-GalpA residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3. GO:0010282 senescence-associated vacuole biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0010282 senescence associated vacuole A lytic vacuole that is maintained at acidic pH and has different tonoplast composition compared to the central vacuole. Found during leaf senescence and develops in the peripheral cytoplasm of cells that contain chloroplast. GO:0034250 positive regulation of cellular amide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034250 positive regulation of amide metabolism Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amides. GO:0010283 pinoresinol reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010283 MetaCyc:RXN-8678|MetaCyc:RXN-8683 Catalysis of the reaction: pinoresinol + NADPH + H+ = lariciresinol + NADP+. GO:0034251 regulation of cellular amide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034251 regulation of amide degradation|regulation of amide breakdown|regulation of amide catabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides. GO:0010280 UDP-L-rhamnose synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010280 MetaCyc:RXN-5482 UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase-4-reductase activity Catalysis of the reaction: UDP-D-glucose + NADPH + H+ = UDP-L-rhamnose + NADP+ + H2O. GO:0034252 negative regulation of cellular amide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034252 negative regulation of amide catabolism|negative regulation of amide degradation|negative regulation of amide breakdown Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides. GO:0010281 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010281 CHEBI:139094 2'-deoxyribose 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139094 CHEBI:139095 2'-deoxyribose 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139095 CHEBI:139090 inositol phosphomannosylinositol-1-phospho-N-acylphytosphingosine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139090 GO:0010297 heteropolysaccharide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010297 heteroglycan binding Interacting selectively and non-covalently with heteropolysaccharides. A heteropolysaccharide is a glycan composed of more than one type of monosaccharide residue. GO:0034242 negative regulation of syncytium formation by plasma membrane fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034242 Any process that decreases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. GO:0010298 dihydrocamalexic acid decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010298 MetaCyc:RXN-8275|RHEA:34807 Catalysis of the reaction: dihydrocamalexic acid = camalexin + CO2 + H+. GO:0034243 regulation of transcription elongation from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034243 regulation of gene-specific transcription elongation from RNA polymerase II promoter|regulation of RNA elongation from RNA polymerase II promoter Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II. GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034244 negative regulation of gene-specific transcription elongation from RNA polymerase II promoter|negative regulation of RNA elongation from RNA polymerase II promoter Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II. GO:0010295 (+)-abscisic acid 8'-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010295 RHEA:12897|KEGG_REACTION:R07202|MetaCyc:1.14.13.93-RXN|EC:1.14.14.137 abscisate,NADPH:oxygen oxidoreductase (8'-hydroxylating)|ABA 8'-hydroxylase activity|(+)-ABA 8'-hydroxylase activity|ABA 8'-Hydroxylase activity, Abscisate 8'-hydroxylase activity|abscisic acid 8'-hydroxylase activity Catalysis of the reaction: (+)-abscisate + H(+) + NADPH + O(2) = (+)-8'-hydroxyabscisate + H(2)O + NADP(+). GO:0034245 mitochondrial DNA-directed RNA polymerase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034245 mitochondrial RNA polymerase holoenzyme complex|mitochondrial RNA polymerase complex A DNA-directed RNA polymerase complex located in the mitochondrion. Mitochondrial RNA polymerase is composed of two subunits, a catalytic core, which resembles the enzymes from bacteriophage T7 and T3, and a specificity factor required for promoter recognition, which is similar to members of the eubacterial sigma factor family. In S. cerevisiae, these are encoded by the nuclear genes RPO41 and MTF1 and the specificity factor, required for promoter recognition and initiation, is not present in the elongating form. GO:0010296 prenylcysteine methylesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010296 RHEA:48520|EC:3.1.1.-|MetaCyc:RXN-8409 Catalysis of the reaction: protein C-terminal S-farnesyl-L-cysteine methyl ester + H2O = protein C-terminal S-farnesyl-L-cysteine + methanol + H+. GO:0034246 mitochondrial transcription factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034246 transcription factor activity, mitochondrial proximal promoter sequence-specific binding|mitochondrial RNA polymerase transcription factor activity, sequence-specific DNA binding|mitochondrial transcription initiation factor activity|mitochondrial RNA polymerase binding promoter specificity activity|mitochondrial transcription factor activity|mitochondrial sequence-specific DNA binding transcription factor activity|mitochondrial RNA polymerase core promoter sequence-specific DNA binding transcription factor activity|mitochondrial RNA polymerase promoter specificity activity|mitochondrial DNA-binding transcription factor activity|mitochondrial sequence-specific DNA-binding transcription factor activity|mitochondrial RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding mitochondrial RNA polymerase transcription factor activity|mitochondrial polymerase transcription factor activity|transcription factor activity, mitochondrial RNA polymerase core promoter proximal region sequence-specific binding|transcription factor activity, mitochondrial RNA polymerase core promoter sequence-specific DNA binding Interacting with the mitochondrial promoter DNA to modulate transcription by the mitochondrial RNA polymerase. GO:0034247 snoRNA splicing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034247 The process of removing sections of a primary snoRNA transcript to remove sequences not present in the mature form of the snoRNA and joining the remaining sections to form the mature form of the snoRNA. GO:0034248 regulation of cellular amide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034248 regulation of amide metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides. GO:0010299 detoxification of cobalt ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010299 Any process that reduces or removes the toxicity of cobalt ion. These include transport of cobalt away from sensitive areas and to compartments or complexes whose purpose is sequestration of cobalt ion. GO:0034249 negative regulation of cellular amide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034249 negative regulation of amide metabolism Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides. GO:0010290 chlorophyll catabolite transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010290 Enables the directed movement of chlorophyll catabolites such as non-fluorescent chlorophyll catabolites (NCCs), from one side of a membrane to the other. GO:0010293 abscisic aldehyde oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010293 KEGG_REACTION:R06957|MetaCyc:1.2.3.14-RXN|RHEA:20529|EC:1.2.3.14 AOdelta|abscisic-aldehyde oxidase activity|AAO3|abscisic-aldehyde:oxygen oxidoreductase activity Catalysis of the reaction: (+)-abscisic aldehyde + H(2)O + O(2) = abscisate + H(2)O(2) + H(+). GO:0010294 abscisic acid glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010294 MetaCyc:RXN-8155|RHEA:31031 Catalysis of the reaction: (+)-abscisate + UDP-D-glucose = abscisic acid glucose ester + UDP. GO:0010291 carotene beta-ring hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010291 beta-carotene hydroxylase activity Catalysis of the reaction: a carotene + a reduced electron acceptor + O2 = C3-hydroxylated carotene + an oxidized electron acceptor + H2O. This is a general reaction to represent the C3 hydroxylation of the beta ring of a carotene. GO:0034240 negative regulation of macrophage fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034240 Any process that stops, prevents, or decreases the frequency, rate or extent of macrophage fusion. CHEBI:139089 N(6)-methyl-2'-deoxyadenosine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139089 GO:0034241 positive regulation of macrophage fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034241 Any process that activates or increases the frequency, rate or extent of macrophage fusion. GO:0010292 GTP:GDP antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010292 Catalysis of the reaction: GTP(out) + GDP(in) = GTP(in) + GDP(out). CHEBI:139064 (15Z)-12-oxophyto-10,15-dienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139064 GO:0034239 regulation of macrophage fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034239 Any process that modulates the frequency, rate or extent of macrophage fusion. GO:0009280 obsolete cell wall inner membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009280 cell wall inner membrane|cytoplasmic membrane OBSOLETE. In Gram-negative bacteria the membrane that separates the cytoplasm from the murein sacculus. GO:0009281 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009281 GO:0009282 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009282 GO:0009283 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009283 GO:0009284 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009284 GO:0009285 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009285 GO:0009275 Gram-positive-bacterium-type cell wall biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009275 20-80nm peptidoglycan-based cell wall|cell wall of Gram-positive Bacteria A layer of peptidoglycan found outside of the cytoplasmic membrane. The peptidoglycan is relatively thick (20-80nm) and retains the primary stain of the Gram procedure, thus cells appear blue after Gram stain. The cell walls often contain teichoic acids (acidic anionic polysaccharides) bound to the peptidoglycan. Examples of this component are found in Gram-positive bacteria. GO:0010264 myo-inositol hexakisphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010264 myo-inositol hexakisphosphate formation|myo-inositol hexakisphosphate biosynthesis|phytate biosynthetic process|phytate biosynthesis|myo-inositol hexakisphosphate anabolism|myo-inositol hexakisphosphate synthesis The chemical reactions and pathways resulting in the formation of phytic acid, myo-inositol hexakisphosphate, a regulator of intracellular signaling, a highly abundant animal anti-nutrient and a phosphate and mineral storage compound in plant seeds. GO:0034231 islet amyloid polypeptide processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034231 islet amyloid polypeptide formation|IAPP formation|islet amyloid peptide processing|islet amyloid peptide formation|IAPP processing The formation of mature islet amyloid polypeptide (IAPP) by posttranslational processing of pro-islet amyloid polypeptide (pro-IAPP). GO:0009276 Gram-negative-bacterium-type cell wall biolink:CellularComponent go-plus goslim_metagenomics http://purl.obolibrary.org/obo/GO_0009276 1-2nm peptidoglycan-based cell wall|cell wall inner membrane The peptidoglycan layer of the Gram-negative cell envelope. In Gram-negative cells the peptidoglycan is relatively thin (1-2nm) and is linked to the outer membrane by lipoproteins. In Gram-negative cells the peptidoglycan is too thin to retain the primary stain in the Gram staining procedure and therefore cells appear red after Gram stain. GO:0034232 ascospore wall chitin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034232 ascospore wall chitin breakdown|ascospore wall chitin catabolism|ascospore wall chitin degradation The chemical reactions and pathways resulting in the breakdown of ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores. GO:0010265 SCF complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010265 The aggregation, arrangement and bonding together of a set of components to form the SKP1-Cullin/Cdc53-F-box protein ubiquitin ligase (SCF) complex. GO:0009277 fungal-type cell wall biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009277 chitin-containing cell wall|beta-glucan-containing cell wall|chitin- and beta-glucan-containing cell wall A rigid yet dynamic structure surrounding the plasma membrane that affords protection from stresses and contributes to cell morphogenesis, consisting of extensively cross-linked glycoproteins and carbohydrates. The glycoproteins may be modified with N- or O-linked carbohydrates, or glycosylphosphatidylinositol (GPI) anchors; the polysaccharides are primarily branched glucans, including beta-linked and alpha-linked glucans, and may also include chitin and other carbohydrate polymers, but not cellulose or pectin. Enzymes involved in cell wall biosynthesis are also found in the cell wall. Note that some forms of fungi develop a capsule outside of the cell wall under certain circumstances; this is considered a separate structure. GO:0010262 somatic embryogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010262 Initiation of a somatic embryo-an embryo arising from previously differentiated somatic cells, rather than from fused haploid gametes. CHEBI:1784 biphenyl-4-amine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_1784 GO:0034233 regulation of cell wall chitin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034233 regulation of cell wall chitin catabolism|regulation of cell wall chitin degradation|regulation of cell wall chitin breakdown Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cell wall chitin. GO:0010263 tricyclic triterpenoid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010263 tricyclic triterpenoid anabolism|tricyclic triterpenoid synthesis|tricyclic triterpenoid formation|tricyclic triterpenoid biosynthesis The chemical reactions and pathways resulting in the formation of tricyclic triterpenoid compounds, terpenoids with 6 isoprene units and 3 carbon rings. GO:0009278 obsolete murein sacculus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009278 murein sacculus OBSOLETE. A peptidoglycan polymer that forms the shape-determining structure of the cell all of Gram-negative bacteria. GO:0034234 regulation of ascospore wall chitin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034234 regulation of ascospore wall chitin catabolism|regulation of ascospore wall chitin degradation|regulation of ascospore wall chitin breakdown Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of ascospore wall chitin. GO:0034235 GPI anchor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034235 glycosylphosphatidylinositol binding Interacting selectively and non-covalently with any glycosylphosphatidylinositol anchor. GPI anchors serve to attach membrane proteins to the lipid bilayer of cell membranes. GO:0009279 cell outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009279 outer membrane of cell A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures. GO:0010268 brassinosteroid homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010268 Any process involved in the maintenance of an internal steady state of brassinosteroids within an organism or cell. GO:0010269 response to selenium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010269 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from selenium ion. GO:0034236 protein kinase A catalytic subunit binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034236 PKA catalytic subunit binding Interacting selectively and non-covalently with one or both of the catalytic subunits of protein kinase A. GO:0010266 response to vitamin B1 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010266 response to thiamine|response to thiamin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B1 stimulus. GO:0034237 protein kinase A regulatory subunit binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034237 protein kinase A anchoring activity|PKA regulatory subunit binding Interacting selectively and non-covalently with one or both of the regulatory subunits of protein kinase A. GO:0034238 macrophage fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034238 The binding and fusion of a macrophage to one or more other cells to form a multinucleated cell. GO:0010267 production of ta-siRNAs involved in RNA interference biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010267 RNA interference, production of ta-siRNAs Cleavage of double-stranded RNA to form trans-acting small interfering RNA molecules (siRNAs) of 21-23 nucleotides. ta-siRNAs arise from PolII genes and function like miRNAs to guide cleavage of target mRNAs. GO:0010260 animal organ senescence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010260 The process that occurs in an animal organ near the end of its active life that is associated with the dismantling of cell components and membranes, and an overall decline in metabolism. GO:0010261 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010261 CHEBI:139057 pyridinium-3-carboxy-5-thiocarboxylic acid mononucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139057 GO:0034230 enkephalin processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034230 peptide enkephalin formation|enkephalin formation|peptide enkephalin processing The formation of mature enkephalin, a pentapeptide hormone involved in regulating pain and nociception in the body by proteolytic processing of enkephalin propeptide. CHEBI:139072 psilocybin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139072 CHEBI:139073 N(5)-phospho-L-glutamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139073 CHEBI:139070 norbaeocystin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139070 CHEBI:139071 baeocystin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139071 GO:0034228 ethanolamine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034228 RHEA:32747 monoethanolamine transmembrane transporter activity|ethanolamine permease activity|2-aminoethanol transmembrane transporter activity Enables the transfer of ethanolamine from one side of a membrane to the other. Ethanolamine (2-aminoethanol, monoethanolamine) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids, such as phosphatidylethanolamine. GO:0009290 DNA import into cell involved in transformation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009290 DNA import into cell|DNA transport into cell during transformation|DNA import into cell involved in transformation|cellular DNA uptake|cellular DNA import during transformation The directed movement of DNA into a cell that contributes to the process of transformation, the uptake of foreign genetic material into a cell. GO:0034229 ethanolamine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034229 2-aminoethanol transport|monoethanolamine transport The directed movement of ethanolamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ethanolamine (2-aminoethanol, monoethanolamine) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids, such as phosphatidylethanolamine. GO:0009291 unidirectional conjugation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009291 The process of unidirectional (polarized) transfer of genetic information involving direct cellular contact between a donor and recipient cell; the contact is followed by the formation of a cellular bridge that physically connects the cells; some or all of the chromosome(s) of one cell ('male') is then transferred into the other cell ('female'); unidirectional conjugation occurs between cells of different mating types. Examples of this process are found in prokaryotes. GO:0009292 genetic transfer biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0009292 genetic exchange In the absence of a sexual life cycle, the process involved in the introduction of genetic information to create a genetically different individual. GO:0009293 transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009293 Wikipedia:Transduction_(genetics) The transfer of genetic information to a bacterium from a bacteriophage or between bacterial or yeast cells mediated by a phage vector. GO:0009294 DNA mediated transformation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009294 DNA-mediated transformation The introduction and uptake of foreign genetic material (DNA or RNA) into a cell, and often the expression of that genetic material. GO:0009295 nucleoid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009295 Wikipedia:Nucleoid The region of a virus, bacterial cell, mitochondrion or chloroplast to which the nucleic acid is confined. GO:0009296 obsolete flagellum assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009296 flagellum biogenesis|flagella assembly|flagellum assembly|flagella biogenesis OBSOLETE. The assembly of a flagellum. In bacteria, this is a whiplike motility appendage present on the surface of some species; in eukaryotes, flagella are threadlike protoplasmic extensions used to propel flagellates and sperm. Flagella are composed of flagellin and have the same basic structure as cilia but are longer in proportion to the cell and present in much smaller numbers. GO:0010275 NAD(P)H dehydrogenase complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010275 NAD(P)H dehydrogenase complex (plastoquinone) assembly The aggregation, arrangement and bonding together of a set of components to form NAD(P)H dehydrogenase complex, which is involved in electron transport from an unidentified electron donor, possibly NAD(P)H or ferredoxin(Fd) to the plastoquinone pool. GO:0009286 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009286 GO:0034220 ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034220 ATP hydrolysis coupled ion transmembrane transport|transmembrane ion transport|ion membrane transport A process in which an ion is transported across a membrane. GO:0010276 phytol kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010276 MetaCyc:RXN-7683|RHEA:38055|EC:2.7.1.- Catalysis of the reaction: phytol + CTP = phytyl monophosphate + CDP + H+. GO:0034221 fungal-type cell wall chitin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034221 fungal-type cell wall chitin biosynthesis|fungal-type cell wall chitin anabolism|fungal-type cell wall chitin synthesis|fungal-type cell wall chitin formation The chemical reactions and pathways resulting in the formation of cell wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of fungal cells. GO:0009287 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009287 GO:0034222 regulation of cell wall chitin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034222 regulation of cell wall chitin metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chitin in a cell wall. GO:0010273 detoxification of copper ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010273 Any process that reduces or removes the toxicity of copper ion. These include transport of copper away from sensitive areas and to compartments or complexes whose purpose is sequestration of copper ion. GO:0009288 bacterial-type flagellum biolink:CellularComponent go-plus goslim_pir|goslim_metagenomics http://purl.obolibrary.org/obo/GO_0009288 flagellin-based flagellum A motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope. GO:0010274 hydrotropism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010274 Wikipedia:Hydrotropism Growth or movement in a sessile organism toward or away from water, as of the roots of a plant. GO:0009289 pilus biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0009289 Wikipedia:Pilus pili|fimbriae|fimbria|fimbrium A proteinaceous hair-like appendage on the surface of bacteria ranging from 2-8 nm in diameter. GO:0034223 regulation of ascospore wall chitin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034223 regulation of ascospore wall chitin anabolism|regulation of ascospore wall chitin synthesis|regulation of ascospore wall chitin formation|regulation of ascospore wall chitin biosynthesis Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ascospore wall chitin. CHEBI:62912 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62912 GO:0034224 cellular response to zinc ion starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034224 cellular response to zinc ion limitation|cellular response to zinc starvation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of zinc ions. GO:0010279 indole-3-acetic acid amido synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010279 IAA amino acid synthetase activity|IAA amino acid conjugate synthetase activity|IAA amido synthetase activity Catalysis of the reaction: indole-3-acetic acid + an amino acid = an indole-3-acetic acid amide conjugate. GO:0034225 obsolete regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034225 regulation of transcription from RNA polymerase II promoter in response to zinc ion limitation|regulation of transcription from RNA polymerase II promoter in response to zinc deficiency OBSOLETE. Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is deprived of zinc ions. CHEBI:62913 EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62913 GO:0010277 chlorophyllide a oxygenase [overall] activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010277 RHEA:30359|EC:1.14.13.122 chlorophyllide a:oxygen 7-oxidoreduction activity|chlorophyllide-a oxygenation activity|CAO activity|chlorophyll a oxygenation activity|chlorophyll b synthesis activity|chlorophyll-b synthesis activity Catalysis of the reactions: chlorophyllide a + O2 + NADPH + H+ = 7-hydroxychlorophyllide a + H2O + NADP+; and 7-hydroxychlorophyllide a + O2 + NADPH + H+ = chlorophyllide b + 2 H2O + NADP+. GO:0034226 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0034226 GO:0034227 tRNA thio-modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034227 MetaCyc:TRNA-S-TRANSFERASE-RXN|EC:2.8.1.4 tRNA sulfurtransferase activity|tRNA thiolation The addition a sulfur atom to a nucleotide in a tRNA molecule. CHEBI:62911 soyasaponin III(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62911 GO:0010278 chloroplast outer membrane translocon biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0010278 The protein transport machinery of the chloroplast outer membrane that contains at least three components Toc159, Toc75 and Toc34, interacts with precursor proteins which are imported into the chloroplast in a GTP dependant manner. CHEBI:62916 soyasaponin I(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62916 CHEBI:139069 4-hydroxytryptamine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139069 CHEBI:62915 sialyltransferase inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62915 GO:0010271 regulation of chlorophyll catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010271 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of chlorophyll. CHEBI:139065 mannosylinositol-1-phosphodihydroceramide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139065 GO:0010272 response to silver ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010272 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silver ion stimulus. CHEBI:139066 mannosylinositol-1-phosphophytoceramide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139066 CHEBI:139068 inositol phosphomannosylinositol-1-phosphophytoceramide(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139068 GO:0010270 photosystem II oxygen evolving complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010270 OEC (PSII) ASSEMBLY The aggregation, arrangement and bonding together of a set of components to form the oxygen evolving complex (OEC) of photosystem II on a thylakoid membrane. The OEC protects the calcium-4 manganese-5 oxide cluster which is bound to the D1 and CP43 proteins. The exact protein composition of the OEC varies between cyanobacteria and plants, and in plants consists of three extrinsic nuclear-encoded polypeptides: PsbO, PsbP and PsbQ. CHEBI:62919 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62919 GO:0048861 leukemia inhibitory factor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048861 leukemia inhibitory factor signalling pathway Any series of molecular signals initiated by the binding of leukemia inhibitory factor to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0048862 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048862 GO:0048863 stem cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048863 Wikipedia:Stem_cell_differentiation The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. GO:0048864 stem cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048864 The process whose specific outcome is the progression of the stem cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to its specific fate. GO:0048865 stem cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048865 The process in which the developmental fate of a cell becomes restricted such that it will develop into a stem cell. GO:0048866 stem cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048866 The process in which a cell becomes capable of differentiating autonomously into a stem cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. GO:0048867 stem cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048867 The process in which a cell becomes capable of differentiating autonomously into a stem cell regardless of its environment; upon determination, the cell fate cannot be reversed. GO:0048868 pollen tube development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048868 The process whose specific outcome is the progression of a pollen tube over time, from its initial formation to a mature structure. CHEBI:37958 dye biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37958 GO:0048860 glioblast division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048860 The process resulting in the physical partitioning and separation of a glioblast into daughter cells. CHEBI:37956 histamine antagonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37956 CHEBI:37957 histaminergic drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37957 CHEBI:37955 H1-receptor antagonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37955 GO:0048869 cellular developmental process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048869 A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition. NCBITaxon:34346 Schizosaccharomycetales organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_34346 GO:0048872 homeostasis of number of cells biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048872 homeostasis of cell number|cell population homeostasis Any biological process involved in the maintenance of the steady-state number of cells within a population of cells. GO:1902708 response to plumbagin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902708 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a plumbagin stimulus. GO:1902709 cellular response to plumbagin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902709 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a plumbagin stimulus. GO:0048873 homeostasis of number of cells within a tissue biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048873 Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in a tissue. GO:1902706 hexose catabolic process to acetate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902706 hexose breakdown to acetate|hexose catabolism to acetate|hexose degradation to acetate|acidogenesis The chemical reactions and pathways resulting in the breakdown of hexose to acetate. GO:0048874 host-mediated regulation of intestinal microbiota composition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048874 host-induced regulation of intestinal microbiota composition|homeostasis of number of cells in a free-living population The biological process involved in maintaining the steady-state number of cells within a population of free-living cells such as the bacteria in the gut. GO:1902707 hexose catabolic process to ethanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902707 hexose breakdown to ethanol|hexose catabolism to ethanol|solventogenesis|hexose degradation to ethanol The chemical reactions and pathways resulting in the breakdown of hexose to ethanol. GO:0048875 chemical homeostasis within a tissue biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048875 Any process involved in the maintenance of the internal steady state of the amount of a chemical at the level of the tissue. GO:0048876 chemical homeostasis within retina biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048876 Any process involved in the maintenance of the internal steady state of the amount of a chemical at the level of the retina. GO:1902704 hexose catabolic process to acetone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902704 hexose degradation to acetone|hexose catabolic process to 2-propanone|solventogenesis|hexose breakdown to acetone|hexose catabolism to acetone The chemical reactions and pathways resulting in the breakdown of hexose to acetone. GO:1902705 hexose catabolic process to butyrate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902705 hexose catabolism to butyrate|hexose breakdown to butyrate|acidogenesis|hexose degradation to butyrate The chemical reactions and pathways resulting in the breakdown of hexose to butyrate. GO:0048877 homeostasis of number of retina cells biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048877 Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in the retina. GO:1902702 hexose catabolic process to propan-2-ol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902702 hexose degradation to propan-2-ol|hexose catabolic process to isopropyl alcohol|solventogenesis|hexose catabolic process to isopropanol|hexose breakdown to propan-2-ol|hexose catabolism to propan-2-ol The chemical reactions and pathways resulting in the breakdown of hexose to propan-2-ol. GO:0048878 chemical homeostasis biolink:BiologicalProcess go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0048878 Any biological process involved in the maintenance of an internal steady state of a chemical. CHEBI:23324 citrullines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23324 GO:1902703 hexose catabolic process to butan-1-ol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902703 hexose catabolism to butan-1-ol|hexose catabolic process to butanol|hexose breakdown to butan-1-ol|solventogenesis|hexose catabolic process to 1-butanol|hexose degradation to butan-1-ol The chemical reactions and pathways resulting in the breakdown of hexose to butan-1-ol. GO:1902700 pentose catabolic process to butan-1-ol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902700 pentose catabolic process to butanol|pentose breakdown to butan-1-ol|solventogenesis|pentose catabolic process to 1-butanol|pentose degradation to butan-1-ol|pentose catabolism to butan-1-ol The chemical reactions and pathways resulting in the breakdown of pentose to butan-1-ol. GO:1902701 pentose catabolic process to propan-2-ol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902701 pentose degradation to propan-2-ol|pentose catabolic process to isopropyl alcohol|solventogenesis|pentose catabolic process to isopropanol|pentose breakdown to propan-2-ol|pentose catabolism to propan-2-ol The chemical reactions and pathways resulting in the breakdown of pentose to propan-2-ol. GO:0048870 cell motility biolink:BiologicalProcess go-plus goslim_drosophila|goslim_generic|goslim_chembl http://purl.obolibrary.org/obo/GO_0048870 cell locomotion|movement of a cell|cell movement Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another. GO:0048871 multicellular organismal homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048871 Any process involved in the maintenance of an internal steady state at the level of the multicellular organism. UBERON:0000170 pair of lungs biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000170 pulmones|lungs|lungs pair|set of lungs The pair of anatomical structures comprised of a left lung and right lung. CHEBI:37963 pyranone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37963 UBERON:0000171 respiration organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000171 breathing organ|apparatus respiratorius organ|organ of apparatus respiratorius|organ of respiratory system|respiratory organ|respiratory system organ|gas exchange organ Organ that functions in gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms. CHEBI:37962 adrenergic agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37962 CHEBI:37965 2H-pyran-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37965 CHEBI:72290 pyrithiamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72290 UBERON:0000178 blood biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000178 whole blood|portion of blood|vertebrate blood A fluid that is composed of blood plasma and erythrocytes. UBERON:0000179 haemolymphatic fluid biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000179 blood or blood analog|circulating fluid Circulating fluid that is part of the hemolymphoid system. Blood, lymph, interstitial fluid or its analogs. CHEBI:72293 monoterpene glycoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72293 UBERON:0000174 excreta biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000174 excretion|portion of excreted substance|waste substance|excreted substance A portion of organism substance that is the product of an excretion process that will be eliminated from the body. An excretion process is elimination by an organism of the waste products that arise as a result of metabolic activity GO:0048883 neuromast primordium migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048883 lateral line primordium migration The migration of a cluster of a relatively undifferentiated cell originating at specific cephalic placodes and depositing proneuromasts along a developing lateral line, from which the neuromasts will develop. GO:1902719 obsolete extracellular sequestering of copper ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902719 extracellular sequestering of copper ion OBSOLETE. The process of binding or confining copper ions in an extracellular area such that they are separated from other components of a biological system. GO:0048884 neuromast development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048884 The process whose specific outcome is the progression of the neuromast over time, from its formation to the mature structure. The neuromast is the sensory organ of the lateral line and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromasts are located superficially on the epithelium or in lateral line canals. GO:1902717 obsolete sequestering of iron ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902717 sequestering of iron ion OBSOLETE. Any process that modulates the frequency, rate or extent of sequestering of iron ion. GO:0048885 neuromast deposition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048885 The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in a developing lateral line. GO:0048886 neuromast hair cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048886 The process in which a relatively unspecialized cell acquires specialized features of a neuromast hair cell. Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons. GO:1902718 obsolete sequestering of copper ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902718 sequestering of copper ion OBSOLETE. Any process that modulates the frequency, rate or extent of sequestering of copper ion. GO:1902715 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902715 GO:0048887 cupula development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048887 The process whose specific outcome is the progression of the cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter. GO:1902716 cell cortex of growing cell tip biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902716 cell cortex of growing cell end Any cell cortex that is part of a growing cell tip. GO:0048888 neuromast mantle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048888 The process in which a relatively unspecialized cell acquires specialized features of a neuromast mantle cell. Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded. GO:0048889 neuromast support cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048889 The process in which a relatively unspecialized cell acquires specialized features of a neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells. GO:1902713 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902713 GO:1902714 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902714 GO:1902711 GABA-A receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902711 A protein complex which is capable of GABA-A receptor activity. In human, it is usually composed of either two alpha, two beta and one gamma chain of the GABA-A receptor subunits or 5 chains of the GABA-A receptor subunits rho1-3 (formally known as GABA-C receptor). GO:1902712 G protein-coupled GABA receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902712 G-protein coupled GABA receptor complex A protein complex which is capable of G protein-coupled GABA receptor activity. In human, it is usually a heterodimer composed of GABA-B receptor subunits 1 and 2. GO:1902710 GABA receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902710 gamma-aminobutyric acid receptor complex A protein complex which is capable of GABA receptor activity. Upon binding of gamma-aminobutyric acid (GABA) it transmits the signal from one side of the membrane to the other to initiate a change in cell activity. Major inhibitory receptor in vertebrate brain. Also found in other vertebrate tissues, invertebrates and possibly in plants. Effective benzodiazepine receptor. GO:0048880 sensory system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048880 The process whose specific outcome is the progression of a sensory system over time from its formation to the mature structure. GO:0048881 mechanosensory lateral line system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048881 LL system development The process whose specific outcome is the progression of the mechanosensory lateral line system over time, from its formation to the mature structure. The mechanosensory lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance. GO:0048882 lateral line development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048882 LL development The process whose specific outcome is the progression of the lateral line over time, from its formation to the mature structure. The lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line develops from cranial ectodermal placodes situated behind the ear and between the eye and ear. CHEBI:37930 phenothiazine antipsychotic drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37930 UBERON:0000160 intestine biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000160 intestinal tract|bowel Segment of the alimentary canal extending from the stomach to the anus and, in humans and other mammals, consists of two segments, the small intestine and the large intestine. CHEBI:37931 10H-phenothiazine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37931 UBERON:0000161 orifice biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000161 ostium|anatomical ostium|anatomical orifice|hilum Anatomical conduit that connects two adjacent body spaces (or a body space with the space surrounding the organism)[FMA,modified]. UBERON:0000162 cloaca biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000162 vent|cloacal chamber Common chamber into which the intestines and excretory system opens. Arises during development in all vertebrates, but in many it becomes subdivided, lost or incorporated into other structures CHEBI:37934 1H-phenothiazine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37934 CHEBI:37935 3H-phenothiazine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37935 CHEBI:37932 phenothiazine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37932 CHEBI:37933 4aH-phenothiazine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37933 UBERON:0000167 oral cavity biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000167 bucca|cavity of mouth|buccal cavity Anatomical cavity at the start of the digestive tract that that is enclosed by the mouth. The boundaries and contents vary depending on the species. In vertebrates, the boundaries are the oral opening, the cheeks, the palate and (if present) the palatoglossal arch - if this is not present then the mouth and pharynx form the oropharyngeal cavity. The buccal cavity contains the teeth, tongue and palate (when present) UBERON:0000168 proximal-distal subdivision of colon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000168 segment of colon A section dividing a colon along a proximal-distal axis. UBERON:0000163 embryonic cloaca biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000163 cloaca endoderm-lined chamber that develops as pouch-like dilation of the caudal end of the hindgut and receives the allantois ventrally and two mesonephric ducts laterally; caudally it ends blindly at the cloacal membrane formed by the union of proctodeal (anal pit) ectoderm and cloacal endoderm, with no intervening mesoderm[MP]. UBERON:0000164 primitive urogenital sinus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000164 sinus urogenitalis|fetal UGS|UGS|urogenital sinus the ventral part of the cloaca remaining after septation of the rectum, which further develops into part of the bladder, part of the prostatic part of the male urethra and the urethra and vestibule in females UBERON:0000165 mouth biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000165 adult mouth|cavital oralis|trophic apparatus|oral region|regio oralis|stomatodaeum|rima oris|stoma|cavum oris|vestibule of mouth|cavitas oris|vestibulum oris|oral vestibule|mouth cavity The proximal portion of the digestive tract, containing the oral cavity and bounded by the oral opening. In vertebrates, this extends to the pharynx and includes gums, lips, tongue and parts of the palate. Typically also includes the teeth, except where these occur elsewhere (e.g. pharyngeal jaws) or protrude from the mouth (tusks). UBERON:0000166 oral opening biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000166 oral part of face|mouth|oral orifice|oral fissure The orifice that connects the mouth to the exterior of the body. GO:0048894 efferent axon development in a lateral line nerve biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048894 The process whose specific outcome is the progression of an efferent axon in a lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in any lateral line nerve. UBERON:0014790 lingual septum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014790 median fibrous septum|tongue septum|septum of tongue|septum of tongue The lingual septum consists of a vertical layer of fibrous tissue, extending throughout the entire length of the median plane of the tongue, though not quite reaching the dorsum. It is thicker behind than in front, and occasionally contains a small fibrocartilage, about 6 mm. in length. It is well displayed by making a vertical section across the organ. UBERON_CORE:site_of site_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/uberon/core#site_of site_of capable_of_has_part c site_of p if c is the bearer of a disposition that is realized by a process that has p as part GO:0048895 lateral line nerve glial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048895 The process in which a relatively unspecialized cell acquires specialized features of a glial cell in a lateral line nerve. UBERON:0014791 musculature of forelimb stylopod biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014791 musculature of arm|muscle group of arm|arm musculature|set of muscles of arm Any collection of muscles that is part of the forelimb stylopod region [Automatically generated definition]. GO:0048896 lateral line nerve glial cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048896 glial cell migration in lateral line nerve The movement of a glial cell along the axons in a lateral line nerve. GO:1902728 positive regulation of growth factor dependent skeletal muscle satellite cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902728 Any process that activates or increases the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta. GO:1902729 negative regulation of proteoglycan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902729 negative regulation of proteoglycan anabolism|down-regulation of proteoglycan anabolism|down-regulation of proteoglycan biosynthetic process|down-regulation of proteoglycan biosynthesis|negative regulation of proteoglycan biosynthesis|negative regulation of proteoglycan synthesis|down-regulation of proteoglycan synthesis|negative regulation of proteoglycan formation|down-regulation of proteoglycan formation|inhibition of proteoglycan biosynthetic process|inhibition of proteoglycan biosynthesis|downregulation of proteoglycan anabolism|downregulation of proteoglycan synthesis|down regulation of proteoglycan anabolism|inhibition of proteoglycan anabolism|downregulation of proteoglycan formation|down regulation of proteoglycan synthesis|inhibition of proteoglycan synthesis|down regulation of proteoglycan formation|down regulation of proteoglycan biosynthesis|down regulation of proteoglycan biosynthetic process|inhibition of proteoglycan formation|downregulation of proteoglycan biosynthetic process|downregulation of proteoglycan biosynthesis Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. UBERON:0014792 musculature of pelvic complex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014792 musculature of lower limb|musculi membri inferioris|muscles of lower limb Any collection of muscles that is part of a pelvic complex. The pelvic complex comprises the pelvic girdle and the associated limb or fin. GO:0048897 myelination of lateral line nerve axons biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048897 The formation of compact myelin sheaths around the axons of a lateral line nerve. GO:1902726 positive regulation of skeletal muscle satellite cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902726 up regulation of satellite cell differentiation|upregulation of satellite cell differentiation|activation of satellite cell differentiation|up-regulation of satellite cell differentiation Any process that activates or increases the frequency, rate or extent of satellite cell differentiation. GO:0048898 anterior lateral line system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048898 ALL system development The process whose specific outcome is the progression of the anterior lateral line system over time, from its formation to the mature structure. The anterior lateral line system develops from cranial ectodermal placodes, situated between the eye and the ear, that give rise to both the neuromasts and the anterior lateral line sensory nerves that innervate the neuromasts. The anterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians and are innervated by several lateral line nerves, which project to the hindbrain. The anterior lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance. GO:1902727 negative regulation of growth factor dependent skeletal muscle satellite cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902727 Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta. GO:0048899 anterior lateral line development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048899 anterior LL development The process whose specific outcome is the progression of the anterior lateral line over time, from its formation to the mature structure. The anterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The anterior lateral line develops from cranial ectodermal placodes situated between the eye and ear. GO:1902724 positive regulation of skeletal muscle satellite cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902724 upregulation of satellite cell proliferation|up-regulation of satellite cell proliferation|activation of satellite cell proliferation|up regulation of satellite cell proliferation Any process that activates or increases the frequency, rate or extent of skeletal muscle satellite cell proliferation. GO:1902725 negative regulation of satellite cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902725 downregulation of satellite cell differentiation|down regulation of satellite cell differentiation|inhibition of satellite cell differentiation|down-regulation of satellite cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell differentiation. GO:1902722 positive regulation of prolactin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902722 upregulation of prolactin secretion|up regulation of prolactin secretion|activation of prolactin secretion|up-regulation of prolactin secretion Any process that activates or increases the frequency, rate or extent of prolactin secretion. CHEBI:37949 azacycloalkane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37949 GO:1902723 negative regulation of skeletal muscle satellite cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902723 inhibition of satellite cell proliferation|down-regulation of satellite cell proliferation|downregulation of satellite cell proliferation|down regulation of satellite cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell proliferation. GO:1902720 obsolete intracellular sequestering of copper ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902720 intracellular sequestering of copper ion OBSOLETE. The process of binding or confining copper ions in an intracellular area such that they are separated from other components of a biological system. CHEBI:37947 benzothiazoles biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37947 GO:1902721 negative regulation of prolactin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902721 down regulation of prolactin secretion|downregulation of prolactin secretion|down-regulation of prolactin secretion|inhibition of prolactin secretion Any process that stops, prevents or reduces the frequency, rate or extent of prolactin secretion. CHEBI:37948 oxaspiro compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37948 UBERON:0014793 musculature of pectoral complex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014793 musculature of upper limb|muscles of upper limb|upper limb musculature|musculi membri superioris|set of muscles of upper limb Any collection of muscles that is part of a pectoral complex. The pectoral complex comprises the pectoral girdle and the associated limb or fin. GO:0048890 lateral line ganglion development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048890 gLL ganglion development The process whose specific outcome is the progression of the lateral line ganglion over time, from its formation to the mature structure. The lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear and behind the ear. UBERON:0014794 pectoral appendage muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014794 Any muscle organ that is part of a pectoral appendage (forelimb or pectoral fin). GO:0048891 lateral line ganglion neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048891 gLL neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a lateral line ganglion neuron. GO:0048892 lateral line nerve development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048892 nLL development The process whose specific outcome is the progression of the lateral line nerve over time, form its formation to the mature structure. Lateral line nerves project primarily to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus. UBERON:0014795 pelvic appendage muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014795 Any muscle organ that is part of a pelvic appendage (hindlimb or pelvic fin). UBERON:0014796 common tendinous ring biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014796 annulus of Zinn|ligament of Zinn|common tendinous ring|annulus tendineus communis|common anular tendon|anulus of Zinn|tendon of Zinn|anulus tendineus communis|anulus tendineus|common annular tendon|anulus tendineus communis A ring of fibrous tissue surrounding the optic nerve at its entrance at the apex of the orbit. GO:0048893 afferent axon development in lateral line nerve biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048893 The process whose specific outcome is the progression of an afferent axon in a lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in any lateral line nerve. CHEBI:37941 clopidogrel biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37941 OBO:GOCHE_26155 substance with plant growth regulator role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_26155 CHEBI:13997 citramalate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_13997 CHEBI:37942 thienopyridine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37942 UBERON:0000151 pectoral fin biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000151 pectoral fins|forefin|omoptérygie@fr|thoracoptérygie@fr|nageoire pectorale@fr Paired fin that is located in the thoracic region of the body. CHEBI:37944 polysaccharide sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37944 UBERON:0000158 membranous layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000158 membranous organ component|membrane UBERON:0000159 anal canal biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000159 canalis analis|mesenteron|cloaca|anal canal|pars analis recti|anatomical anal canal|cloacal chamber|anus|anal pad|anal canal viewed anatomically The terminal part of the large intestine, continuous proximally with the rectum and distally terminates with the anus. UBERON:0000152 pelvic fin biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000152 pelvic fins|nageoire pelvienne@fr|ischioptérygie@fr Paired fin located in the abdominal position of the body. UBERON:0000153 anterior region of body biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000153 UBERON:0000154 posterior region of body biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0000154 GO:1902739 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902739 GO:1902737 dendritic filopodium biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902737 dendrite filopodium A small, membranous protrusion found primarily on dendritic stretches of developing neurons. May receive synaptic input, and can develop into dendritic spines. GO:1902738 regulation of chondrocyte differentiation involved in endochondral bone morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902738 Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage. GO:1902735 negative regulation of receptor-mediated virion attachment to host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902735 downregulation of receptor-mediated virion attachment to host cell|down regulation of receptor-mediated virion attachment to host cell|downregulation of virion attachment, binding of host cell surface receptor|inhibition of receptor-mediated virion attachment to host cell|down regulation of virion attachment, binding of host cell surface receptor|inhibition of virion attachment, binding of host cell surface receptor|down-regulation of receptor-mediated virion attachment to host cell|down-regulation of virion attachment, binding of host cell surface receptor|negative regulation of virion attachment, binding of host cell surface receptor Any process that stops, prevents or reduces the frequency, rate or extent of receptor-mediated virion attachment to host cell. GO:1902736 positive regulation of receptor-mediated virion attachment to host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902736 positive regulation of virion attachment, binding of host cell surface receptor|up regulation of virion attachment, binding of host cell surface receptor|upregulation of receptor-mediated virion attachment to host cell|upregulation of virion attachment, binding of host cell surface receptor|up-regulation of receptor-mediated virion attachment to host cell|activation of receptor-mediated virion attachment to host cell|up-regulation of virion attachment, binding of host cell surface receptor|activation of virion attachment, binding of host cell surface receptor|up regulation of receptor-mediated virion attachment to host cell Any process that activates or increases the frequency, rate or extent of receptor-mediated virion attachment to host cell. GO:1902733 regulation of growth plate cartilage chondrocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902733 Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the growth of a bone. A chondrocyte is a polymorphic cell that forms cartilage. GO:1902734 regulation of receptor-mediated virion attachment to host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902734 regulation of virion attachment, binding of host cell surface receptor Any process that modulates the frequency, rate or extent of receptor-mediated virion attachment to host cell. GO:1902731 negative regulation of chondrocyte proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902731 inhibition of chondrocyte proliferation|negative regulation of chondrocyte cell proliferation|down-regulation of chondrocyte cell proliferation|downregulation of cartilage cell proliferation|down regulation of cartilage cell proliferation|inhibition of cartilage cell proliferation|down regulation of chondrocyte proliferation|downregulation of chondrocyte cell proliferation|downregulation of chondrocyte proliferation|down regulation of chondrocyte cell proliferation|inhibition of chondrocyte cell proliferation|down-regulation of chondrocyte proliferation|down-regulation of cartilage cell proliferation|negative regulation of cartilage cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of the multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population. A chondrocyte is a polymorphic cell that forms cartilage. CHEBI:37914 27-hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37914 GO:1902732 positive regulation of chondrocyte proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902732 up-regulation of chondrocyte cell proliferation|activation of chondrocyte cell proliferation|positive regulation of cartilage cell proliferation|up-regulation of chondrocyte proliferation|up regulation of cartilage cell proliferation|positive regulation of chondrocyte cell proliferation|up regulation of chondrocyte cell proliferation|upregulation of chondrocyte proliferation|upregulation of cartilage cell proliferation|up regulation of chondrocyte proliferation|upregulation of chondrocyte cell proliferation|activation of chondrocyte proliferation|up-regulation of cartilage cell proliferation|activation of cartilage cell proliferation Any process that increases the frequency, rate or extent of the multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population. A chondrocyte is a polymorphic cell that forms cartilage. GO:1902730 positive regulation of proteoglycan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902730 upregulation of proteoglycan synthesis|upregulation of proteoglycan formation|up-regulation of proteoglycan anabolism|activation of proteoglycan anabolism|up regulation of proteoglycan biosynthetic process|up regulation of proteoglycan biosynthesis|up-regulation of proteoglycan synthesis|activation of proteoglycan biosynthesis|activation of proteoglycan biosynthetic process|positive regulation of proteoglycan biosynthesis|activation of proteoglycan synthesis|up-regulation of proteoglycan formation|activation of proteoglycan formation|positive regulation of proteoglycan anabolism|up regulation of proteoglycan anabolism|positive regulation of proteoglycan synthesis|up-regulation of proteoglycan biosynthetic process|up-regulation of proteoglycan biosynthesis|up regulation of proteoglycan synthesis|positive regulation of proteoglycan formation|up regulation of proteoglycan formation|upregulation of proteoglycan anabolism|upregulation of proteoglycan biosynthetic process|upregulation of proteoglycan biosynthesis Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. CHEBI:37919 aryl sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37919 CHEBI:13941 carbamate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_13941 CHEBI:37912 hydroxycoumarin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37912 CHEBI:37911 indane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37911 GO:1902748 positive regulation of lens fiber cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902748 up regulation of lens fibre cell differentiation|activation of lens fibre cell differentiation|positive regulation of lens fibre cell differentiation|up-regulation of lens fiber cell differentiation|up-regulation of lens fibre cell differentiation|upregulation of lens fiber cell differentiation|upregulation of lens fibre cell differentiation|up regulation of lens fiber cell differentiation|activation of lens fiber cell differentiation Any process that activates or increases the frequency, rate or extent of lens fiber cell differentiation. GO:1902749 regulation of cell cycle G2/M phase transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902749 Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle. GO:1902746 regulation of lens fiber cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902746 regulation of lens fibre cell differentiation Any process that modulates the frequency, rate or extent of lens fiber cell differentiation. GO:1902747 negative regulation of lens fiber cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902747 down-regulation of lens fiber cell differentiation|negative regulation of lens fibre cell differentiation|down-regulation of lens fibre cell differentiation|inhibition of lens fiber cell differentiation|inhibition of lens fibre cell differentiation|down regulation of lens fiber cell differentiation|downregulation of lens fiber cell differentiation|down regulation of lens fibre cell differentiation|downregulation of lens fibre cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of lens fiber cell differentiation. GO:1902744 negative regulation of lamellipodium organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902744 down-regulation of lamellipodium organization|downregulation of lamellipodium organization|down regulation of lamellipodium organization|inhibition of lamellipodium organization Any process that stops, prevents or reduces the frequency, rate or extent of lamellipodium organization. GO:1902745 positive regulation of lamellipodium organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902745 activation of lamellipodium organization|up regulation of lamellipodium organization|upregulation of lamellipodium organization|up-regulation of lamellipodium organization Any process that activates or increases the frequency, rate or extent of lamellipodium organization. GO:1902742 apoptotic process involved in development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902742 type I programmed cell death involved in development of an anatomical structure|apoptosis involved in development of an anatomical structure|apoptosis activator activity involved in development of an anatomical structure|induction of apoptosis involved in development of an anatomical structure|activation of apoptosis involved in development of an anatomical structure|programmed cell death by apoptosis involved in anatomical structure development|commitment to apoptosis involved in anatomical structure development|apoptotic programmed cell death involved in development of an anatomical structure|apoptotic process involved in development of an anatomical structure|apoptotic cell death involved in development of an anatomical structure|signaling (initiator) caspase activity involved in anatomical structure development|apoptotic program involved in anatomical structure development|induction of apoptosis by p53 involved in anatomical structure development|apoptotic process involved in anatomical structure development|apoptosis signaling involved in anatomical structure development|programmed cell death by apoptosis involved in development of an anatomical structure|commitment to apoptosis involved in development of an anatomical structure|type I programmed cell death involved in anatomical structure development|signaling (initiator) caspase activity involved in development of an anatomical structure|apoptosis activator activity involved in anatomical structure development|apoptosis involved in anatomical structure development|induction of apoptosis involved in anatomical structure development|apoptotic program involved in development of an anatomical structure|induction of apoptosis by p53 involved in development of an anatomical structure|activation of apoptosis involved in anatomical structure development|apoptotic programmed cell death involved in anatomical structure development|apoptotic cell death involved in anatomical structure development|apoptosis signaling involved in development of an anatomical structure Any apoptotic process that is involved in anatomical structure development. GO:1902743 regulation of lamellipodium organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902743 Any process that modulates the frequency, rate or extent of lamellipodium organization. GO:1902740 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902740 GO:1902741 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902741 CHEBI:37921 pyridazines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37921 GO:1902759 Mo(VI)-molybdopterin cytosine dinucleotide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902759 Mo(VI)-molybdopterin cytosine dinucleotide metabolism The chemical reactions and pathways involving Mo(VI)-molybdopterin cytosine dinucleotide. GO:1902757 bis(molybdopterin guanine dinucleotide)molybdenum metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902757 bis(molybdopterin guanine dinucleotide)molybdenum metabolism The chemical reactions and pathways involving bis(molybdopterin guanine dinucleotide)molybdenum. GO:1902758 bis(molybdopterin guanine dinucleotide)molybdenum biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902758 MetaCyc:PWY-5964 bis(molybdopterin guanine dinucleotide)molybdenum biosynthesis|bis(molybdopterin guanine dinucleotide)molybdenum anabolism|bis(molybdopterin guanine dinucleotide)molybdenum synthesis|bis(molybdopterin guanine dinucleotide)molybdenum formation|bis-Mo-molybdopterin-guanine dinucleotide cofactor biosynthetic process The chemical reactions and pathways resulting in the formation of bis(molybdopterin guanine dinucleotide)molybdenum. GO:1902755 sulfurated eukaryotic molybdenum cofactor(2-) metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902755 sulfurated eukaryotic molybdenum cofactor(2-) metabolism The chemical reactions and pathways involving sulfurated eukaryotic molybdenum cofactor(2-). GO:1902756 sulfurated eukaryotic molybdenum cofactor(2-) biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902756 Reactome:R-HSA-947581|MetaCyc:PWY-6476 sulfurated eukaryotic molybdenum cofactor(2-) anabolism|sulfurated eukaryotic molybdenum cofactor(2-) synthesis|sulfurated eukaryotic molybdenum cofactor(2-) formation|sulfurated eukaryotic molybdenum cofactor(2-) biosynthesis The chemical reactions and pathways resulting in the formation of sulfurated eukaryotic molybdenum cofactor(2-). GO:1902753 negative regulation of renal amino acid absorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902753 down regulation of renal amino acid absorption|downregulation of renal amino acid absorption|down-regulation of renal amino acid absorption|inhibition of renal amino acid absorption Any process that stops, prevents or reduces the frequency, rate or extent of renal amino acid absorption. GO:1902754 positive regulation of renal amino acid absorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902754 upregulation of renal amino acid absorption|up regulation of renal amino acid absorption|activation of renal amino acid absorption|up-regulation of renal amino acid absorption Any process that activates or increases the frequency, rate or extent of renal amino acid absorption. GO:1902751 positive regulation of cell cycle G2/M phase transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902751 upregulation of cell cycle G2/M phase transition|activation of cell cycle G2/M phase transition|up-regulation of cell cycle G2/M phase transition|up regulation of cell cycle G2/M phase transition Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle. GO:1902752 regulation of renal amino acid absorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902752 Any process that modulates the frequency, rate or extent of renal amino acid absorption. GO:1902750 negative regulation of cell cycle G2/M phase transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902750 down regulation of cell cycle G2/M phase transition|inhibition of cell cycle G2/M phase transition|down-regulation of cell cycle G2/M phase transition|downregulation of cell cycle G2/M phase transition Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle. NCBITaxon:34353 Dipodascaceae organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_34353 anamorphic Dipodascaceae GO:1902768 isoprenoid biosynthetic process via 1-deoxy-D-xylulose 5-phosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902768 isoprenoid formation via 1-deoxy-D-xylulose 5-phosphate|isoprenoid synthesis via 1-deoxy-D-xylulose 5-phosphate|isoprenoid anabolism via 1-deoxy-D-xylulose 5-phosphate|isoprenoid biosynthesis via 1-deoxy-D-xylulose 5-phosphate The chemical reactions and pathways resulting in the formation of isoprenoid via 1-deoxy-D-xylulose 5-phosphate. GO:1902769 regulation of choline O-acetyltransferase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902769 regulation of CHOACTase activity|regulation of choline acetylase activity|regulation of acetyl-CoA:choline O-acetyltransferase activity|regulation of choline acetyltransferase activity Any process that modulates the frequency, rate or extent of choline O-acetyltransferase activity. GO:1902766 skeletal muscle satellite cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902766 The orderly movement of a skeletal muscle satellite cell from one site to another. Migration of these cells is a key step in the process of growth and repair of skeletal muscle cells. GO:1902767 isoprenoid biosynthetic process via mevalonate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902767 isoprenoid formation via mevalonate|isoprenoid synthesis via mevalonate|isoprenoid anabolism via mevalonate|isoprenoid biosynthesis via mevalonate The chemical reactions and pathways resulting in the formation of isoprenoid via mevalonate. GO:1902764 positive regulation of embryonic skeletal joint development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902764 upregulation of embryonic skeletal joint development|up-regulation of embryonic skeletal joint development|activation of embryonic skeletal joint development|up regulation of embryonic skeletal joint development Any process that activates or increases the frequency, rate or extent of embryonic skeletal joint development. CHEBI:37903 lysyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37903 GO:1902765 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902765 CHEBI:37909 oligosaccharide sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37909 CHEBI:13956 ceramide 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_13956 GO:1902762 regulation of embryonic skeletal joint development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902762 Any process that modulates the frequency, rate or extent of embryonic skeletal joint development. GO:1902763 negative regulation of embryonic skeletal joint development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902763 downregulation of embryonic skeletal joint development|down regulation of embryonic skeletal joint development|inhibition of embryonic skeletal joint development|down-regulation of embryonic skeletal joint development Any process that stops, prevents or reduces the frequency, rate or extent of embryonic skeletal joint development. GO:1902760 Mo(VI)-molybdopterin cytosine dinucleotide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902760 MetaCyc:PWY-6476 Mo(VI)-molybdopterin cytosine dinucleotide anabolism|Mo(VI)-molybdopterin cytosine dinucleotide synthesis|Mo-molybdopterin-cytosine-dinucleotide cofactor biosynthetic process|Mo(VI)-molybdopterin cytosine dinucleotide formation|Mo(VI)-molybdopterin cytosine dinucleotide biosynthesis The chemical reactions and pathways resulting in the formation of Mo(VI)-molybdopterin cytosine dinucleotide. GO:1902761 positive regulation of chondrocyte development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902761 up-regulation of chondrocyte development|upregulation of chondrocyte development|up regulation of chondrocyte development|activation of chondrocyte development Any process that activates or increases the frequency, rate or extent of chondrocyte development. GO:1902770 negative regulation of choline O-acetyltransferase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902770 downregulation of acetyl-CoA:choline O-acetyltransferase activity|down-regulation of CHOACTase activity|downregulation of choline acetyltransferase activity|negative regulation of CHOACTase activity|down-regulation of choline acetylase activity|downregulation of choline O-acetyltransferase activity|negative regulation of choline acetylase activity|down regulation of choline acetyltransferase activity|down regulation of choline O-acetyltransferase activity|inhibition of choline acetyltransferase activity|down-regulation of acetyl-CoA:choline O-acetyltransferase activity|negative regulation of acetyl-CoA:choline O-acetyltransferase activity|inhibition of choline O-acetyltransferase activity|downregulation of CHOACTase activity|downregulation of choline acetylase activity|down regulation of CHOACTase activity|inhibition of acetyl-CoA:choline O-acetyltransferase activity|down regulation of choline acetylase activity|inhibition of CHOACTase activity|inhibition of choline acetylase activity|down-regulation of choline acetyltransferase activity|negative regulation of choline acetyltransferase activity|down-regulation of choline O-acetyltransferase activity|down regulation of acetyl-CoA:choline O-acetyltransferase activity Any process that stops, prevents or reduces the frequency, rate or extent of choline O-acetyltransferase activity. CHEBI:37902 methionyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37902 CHEBI:37900 threonyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37900 OBO:GOCHE_26115 substance with phytoalexin role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_26115 GO:0010404 cell wall hydroxyproline-rich glycoprotein metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010404 cell wall hydroxyproline-rich glycoprotein metabolism The chemical reactions and pathways involving a cell wall hydroxyproline-rich glycoprotein that consist of a core-protein backbone O-glycosylated by one or more complex carbohydrates. GO:0010405 arabinogalactan protein metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010405 arabinogalactan protein metabolism The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein, which is composed of a group of core protein of highly varying length and domain complexity. These are O-glycosylated at one or more hydroxyproline residues by arabinogalactan (AG) type II groups, which consist of (1->3)-beta-galactan and (1->6)-beta-linked galactan chains connected to each other by (1->3,1->6)-linked branch points, O-3 and O-6 positions substituted with terminal arabinosyl residues. Also, rhamnose, fucose, glucuronic and galacturonic acid can be present in the glycan structures. GO:0010402 pectic arabinan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010402 pectic arabinan metabolism The chemical reactions and pathways involving pectic arabinan, a polymer with an alpha-(1->5)-linked L-arabinofuranose (Araf) backbone that can be substituted with Araf-alpha-(1->2)-, Araf-alpha-(1->3)-, and/or Araf-alpha-(1->3)-Araf-alpha-(1->3)-side chains. Arabinan can be found as a side chain of the pectin rhamnogalacturonan I. GO:0010403 pectic arabinogalactan I metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010403 pectic arabinogalactan I metabolism The chemical reactions and pathways involving pectic arabinogalactan I, an alpha-(1,4)-linked D-galactopyranose backbone that is substituted with alpha-l-Araf residues via the O-3 of the D-galactose residues. Arabinogalactan I can be found as a side chain of rhamnogalacturonan I. GO:0010408 fasciclin-like arabinogalactan protein metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010408 fasciclin-like arabinogalactan protein metabolism The chemical reactions and pathways involving the cell wall arabinogalactan II glycoprotein variant which contains both an arabinogalactan protein (AGP) motif and a fasciclin domain. GO:0010409 extensin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010409 extensin metabolism The chemical reactions and pathways involving extensins, a group of 60-90 kDNA hydroxyproline (Hyp)-rich glycoproteins whose polypeptide backbone consists of many repeats of structural Ser(Hyp)4-6 motifs, with heavily glycosylated 1-4 arabinose residues O-linked to contiguous stretches of Hyp residues, with most of the Ser residues being O-galactosylated. GO:0010406 classical arabinogalactan protein metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010406 classical-arabinogalactan protein metabolism The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein, which is composed of a group of core protein containing Hyp, Ala, Ser, Thr and Gly as the major amino acid constituents, and the C-terminus is GPI anchored. GO:0010407 non-classical arabinogalactan protein metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010407 non-classical arabinogalactan protein metabolism The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein where other amino acids besides Hyp, Ala, Ser, Thr and Gly can be present and grouped into regions, such as a Cys-rich or Asn-rich domains. GO:0009410 response to xenobiotic stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009410 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xenobiotic compound stimulus. Xenobiotic compounds are compounds foreign to living organisms. CHEBI:62885 adenosine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62885 GO:0009411 response to UV biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009411 response to ultraviolet light stimulus|response to UV light stimulus|response to ultraviolet radiation stimulus|response to UV radiation stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers. GO:0010400 rhamnogalacturonan I side chain metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010400 rhamnogalacturonan I side chain metabolism The chemical reactions and pathways involving the side chains of the pectin, rhamnogalacturonan I. GO:0009412 obsolete response to heavy metal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009412 response to heavy metal OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heavy metal stimulus. Heavy metals are those metals that can form a coordination bond with a protein; this definition includes the following biologically relevant heavy metals: Cd, Co, Cu, Fe, Hg, Mn, Mo, Ni, V, W, Zn. GO:0010401 pectic galactan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010401 pectic galactan metabolism The chemical reactions and pathways involving galactan, a polymer of D-galactosyl units that can be found as a side chain of the pectin rhamnogalacturonan I. GO:0009413 response to flooding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009413 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating flooding, short-term immersion in water. GO:0009414 response to water deprivation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009414 response to drought|response to dehydration|drought tolerance|response to thirst Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water. CHEBI:62889 organic diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62889 GO:0009415 response to water biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009415 response to water stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water. GO:0009416 response to light stimulus biolink:BiologicalProcess go-plus goslim_plant http://purl.obolibrary.org/obo/GO_0009416 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light. GO:0009417 obsolete fimbrin biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009417 fimbrin OBSOLETE. A class of proteins that are the subunit components of fimbria. GO:0009418 pilus shaft biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009418 fimbrial shaft The long, slender, mid section of a pilus. GO:0009419 pilus tip biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009419 fimbrial tip The pointed extremity furthest from the cell of a pilus. GO:0010415 unsubstituted mannan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010415 unsubstituted mannan metabolism The chemical reactions and pathways involving the mannan backbone, the unsubstituted polymer of D-mannose units. GO:0010416 arabinoxylan-containing compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010416 arabinoxylan metabolism|arabinoxylan metabolic process The chemical reactions and pathways involving an arabinoxylan, a polymer containing a beta-1,4-linked D-xylose backbone decorated with arabinose side units. CHEBI:62890 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62890 GO:0010413 glucuronoxylan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010413 glucuronoxylan metabolism The chemical reactions and pathways involving xylan, a polymer containing a beta-(1->4)-linked D-xylose backbone decorated with glucuronic acid side units. GO:0010414 glucuronoarabinoxylan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010414 glucuronoarabinoxylan metabolism The chemical reactions and pathways involving xylan, a polymer containing a beta-(1->4)-linked D-xylose backbone decorated with glucuronic acid and arabinose side units. GO:0010419 rhamnogalacturonan II side chain metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010419 rhamnogalacturonan II side chain metabolism The chemical reactions and pathways involving the side chains of pectic rhamnogalacturonan II. A number of structurally distinct di- and oligosaccharides can be attached to the C-3 and C-2 of the backbone, respectively. CHEBI:62894 organic triphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62894 CHEBI:23286 cis-3,4-dihydrophenanthrene-3,4-diol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23286 GO:0010417 glucuronoxylan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010417 glucuronoxylan synthesis|glucuronoxylan formation|glucuronoxylan biosynthesis|glucuronoxylan anabolism The chemical reactions and pathways resulting in the formation of glucuronoxylan, a polymer containing a beta-1,4-linked D-xylose backbone substituted with glucuronic acid residues. GO:0010418 rhamnogalacturonan II backbone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010418 rhamnogalacturonan II backbone metabolism The chemical reactions and pathways involving the backbone structure of pectic rhamnogalacturonan II. The back bone contains at least 8 1,4-linked alpha-D-GalpA residues. CHEBI:62898 isopentenyl alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62898 GO:0009420 bacterial-type flagellum filament biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009420 flagellar filament|flagellin-based flagellum filament The long (approximately 20 nm), thin external structure of the bacterial-type flagellum, which acts as a propeller. GO:0009421 bacterial-type flagellum filament cap biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009421 flagellar filament cap|flagellin-based flagellum filament cap The proteinaceous structure at the distal tip of the bacterial-type flagellar filament. GO:0010411 xyloglucan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010411 xyloglucan metabolism The chemical reactions and pathways involving xyloglucan, the cross-linking glycan composed of (1->4)-beta-D-glucan backbone substituted at regular intervals with beta-D-xylosyl-(1->6) residues, which is present in the primary cell wall of most higher plants. GO:0009422 bacterial-type flagellum hook-filament junction biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009422 flagellar hook-filament junction The region of the bacterial-type flagellum where the hook and filament meet. GO:0009423 chorismate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009423 MetaCyc:ARO-PWY chorismate anabolism|chorismate synthesis|shikimate anabolism|chorismate formation|shikimate synthesis|shikimate pathway|chorismate biosynthesis|shikimate biosynthesis|shikimate biosynthetic process The chemical reactions and pathways resulting in the formation of the unsymmetrical ether derived from phosphoenolpyruvate and 5-phosphoshikimic acid formed as an intermediate in the biosynthesis of aromatic amino acids and many other compounds. GO:0010412 mannan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010412 mannan metabolism The chemical reactions and pathways involving mannan, a group of polysaccharides containing a backbone composed of a polymer of D-mannose units. GO:0009424 bacterial-type flagellum hook biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009424 flagellin-based flagellum hook|flagellar hook The portion of the bacterial-type flagellum that connects the filament to the basal body. CHEBI:62899 (R,Z)- 2-carboxylato-4-methyl-5-[(2-phosphonatooxy)ethylidene]-2,5-dihydrothiazole(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62899 GO:0009425 bacterial-type flagellum basal body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009425 flagellin-based flagellum basal body|flagellar basal body One of the three major substructures of the bacterial-type flagellum, the basal body is embedded in the cell envelope (the plasma membrane, peptidoglycan cell wall, and, if one is present, the outer membrane); it houses the secretion apparatus that exports the more distal components and the flagellar motor. GO:0010410 hemicellulose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010410 hemicellulose metabolism The chemical reactions and pathways involving hemicelluloses, plant cell wall polysaccharides that have a backbone of 1,4-linked beta-D-pyranosyl residues in which O4 is in the equatorial orientation. Many different hemicelluloses usually occur intermixed with each molecular type representing different degrees of polymerization and contain many different sugar monomers, which can include glucose, xylose, mannose, galactose, and arabinose. Hemicelluloses also contain most of the D-pentose sugars and occasionally small amounts of L-sugars as well. Xylose is always the sugar monomer present in the largest amount, but mannuronic acid and galacturonic acid also tend to be present. GO:0009426 bacterial-type flagellum basal body, distal rod biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009426 flagellar basal body, distal rod|flagellin-based flagellum basal body, distal rod The portion of the central rod of the bacterial-type flagellar basal body that is distal to the cell membrane; spans most of the distance between the inner and outer membranes. GO:0009427 bacterial-type flagellum basal body, distal rod, L ring biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009427 flagellar basal body, distal rod, L ring|flagellin-based flagellum basal body, distal rod, L ring One of the rings of the bacterial-type flagellar basal body; anchors the basal body to the outer membrane. GO:0009428 bacterial-type flagellum basal body, distal rod, P ring biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009428 flagellin-based flagellum basal body, distal rod, P ring|flagellar basal body, distal rod, P ring One of the rings of the bacterial-type flagellar basal body; anchors the basal body to the peptidoglycan layer. GO:0009429 bacterial-type flagellum basal body, proximal rod biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009429 flagellar basal body, proximal rod|flagellin-based flagellum basal body, proximal rod The portion of the central rod of the bacterial-type flagellar basal body that is proximal to the cell membrane; the proximal rod connects the distal rod to the flagellar motor. CHEBI:23252 cinnamic acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23252 CHEBI:37897 valyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37897 CHEBI:37898 tyrosyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37898 CHEBI:37890 alpha-adrenergic antagonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37890 CHEBI:47214 (23S)-23,25-dihydroxycalciol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47214 GO:0009400 obsolete signal transducer, downstream of receptor, with serine/threonine phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009400 receptor signaling protein serine/threonine phosphatase activity|receptor signalling protein serine/threonine phosphatase activity OBSOLETE. Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate. GO:0009401 phosphoenolpyruvate-dependent sugar phosphotransferase system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009401 PTS system The uptake and phosphorylation of specific carbohydrates from the extracellular environment; uptake and phosphorylation are coupled, making the PTS a link between the uptake and metabolism of sugars; phosphoenolpyruvate is the original phosphate donor; phosphoenolpyruvate passes the phosphate via a signal transduction pathway, to enzyme 1 (E1), which in turn passes it on to the histidine protein, HPr; the next step in the system involves sugar-specific membrane-bound complex, enzyme 2 (EII), which transports the sugar into the cell; it includes the sugar permease, which catalyzes the transport reactions; EII is usually divided into three different domains, EIIA, EIIB, and EIIC. GO:0009402 obsolete toxin resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009402 toxin resistance OBSOLETE. (Was not defined before being made obsolete). GO:0009403 toxin biosynthetic process biolink:BiologicalProcess go-plus goslim_metagenomics http://purl.obolibrary.org/obo/GO_0009403 toxin formation|toxin biosynthesis|toxin anabolism|toxin synthesis The chemical reactions and pathways resulting in the formation of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism. GO:0009404 toxin metabolic process biolink:BiologicalProcess go-plus goslim_pir|goslim_aspergillus http://purl.obolibrary.org/obo/GO_0009404 toxin metabolism The chemical reactions and pathways involving a toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism. GO:0009405 pathogenesis biolink:BiologicalProcess go-plus goslim_chembl|goslim_candida|goslim_aspergillus|goslim_metagenomics http://purl.obolibrary.org/obo/GO_0009405 virulence The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism. GO:0009406 obsolete virulence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009406 virulence OBSOLETE. (Was not defined before being made obsolete). GO:0009407 toxin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009407 toxin catabolism|toxin degradation|toxin breakdown The chemical reactions and pathways resulting in the breakdown of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism. GO:0009408 response to heat biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0009408 response to heat shock Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism. GO:0009409 response to cold biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009409 freezing tolerance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism. CHEBI:23232 chromenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23232 CHEBI:23238 chromones biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23238 CHEBI:23239 chromopeptide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23239 CHEBI:23237 chromium molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23237 CHEBI:23230 chromanes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23230 CHEBI:37875 acyl sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37875 CHEBI:37876 O-acylglucosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37876 CHEBI:37878 glucosamine sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37878 CHEBI:23245 cinnamaldehydes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23245 CHEBI:23243 cineole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23243 CHEBI:23247 cinnamamides biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23247 CHEBI:23248 cinnamate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_23248 CHEBI:23240 chromophore biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23240 CHEBI:37886 adrenergic agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37886 CHEBI:37887 adrenergic antagonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37887 CHEBI:37888 (1R,6S)-1,6-dihydroxycyclohexa-2,4-dienecarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37888 CHEBI:37889 (1S,6R)-1,6-dihydroxycyclohexa-2,4-dienecarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37889 CHEBI:541975 epiandrosterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_541975 CHEBI:23213 choline ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23213 CHEBI:23216 choline sulfates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23216 CHEBI:23217 cholines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23217 UBERON:0014401 renal venous blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014401 kidney venous blood vessel|kidney venous system|venous blood vessel of kidney Any member of the network of tubes that return blood from the renal tissues to the systemic circulation. UBERON:0014402 sex-specific anatomical structure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014402 gender-specific|sex-specific|gender-specific anatomical structure A part of the body present only in a specific gender. UBERON:0014403 male anatomical structure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014403 male-specific structure|male-specific A part of the body present only in males. CHEBI:37859 sulfenate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37859 UBERON:0014404 female anatomical structure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014404 A part of the body present only in females. UBERON:0014400 hepatic sinusoidal space biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014400 lumen of hepatic sinusoid A sinusoidal space that is part of a hepatic sinusoid. CHEBI:37852 organoammonium sulfate salt biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37852 CHEBI:37858 sulfenic acid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37858 CHEBI:23218 choloyl-CoAs biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23218 CHEBI:23219 bile acid taurine conjugate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23219 CHEBI:37864 thioperoxol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37864 CHEBI:37862 O-sulfoamino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37862 CHEBI:37863 chalcoperoxol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37863 CHEBI:37868 octanol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37868 CHEBI:23229 chromanol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23229 CHEBI:37861 nucleotide-sugar sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37861 GO:0034459 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0034459 GO:0009495 obsolete thioredoxin-like 2Fe-2S ferredoxin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009495 thioredoxin-like 2Fe-2S ferredoxin OBSOLETE. (Was not defined before being made obsolete). GO:0010484 H3 histone acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010484 Catalysis of the reaction: acetyl-CoA + histone H3 = CoA + acetyl-histone H3. GO:0034451 centriolar satellite biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034451 A small (70-100 nm) cytoplasmic granule that contains a number of centrosomal proteins; centriolar satellites traffic toward microtubule minus ends and are enriched near the centrosome. GO:0034452 dynactin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034452 Interacting selectively and non-covalently with any part of a dynactin complex; dynactin is a large protein complex that activates dynein-based motor activity. GO:0009496 plastoquinol--plastocyanin reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009496 RHEA:22148|EC:7.1.1.6|MetaCyc:PLASTOQUINOL--PLASTOCYANIN-REDUCTASE-RXN|KEGG_REACTION:R03817 plastoquinol/plastocyanin oxidoreductase activity|cytochrome b6f complex activity|cytochrome b6f|plastoquinol-plastocyanin reductase activity|plastoquinol:oxidized-plastocyanin oxidoreductase activity Catalysis of the reaction: 2 H(+)[side 1] + 2 oxidized plastocyanin + plastoquinol-1 = 2 H(+)[side 2] + 2 reduced plastocyanin + plastoquinone. This reaction involves the concomitant transfer of 2 H+ ions across a membrane. GO:0010485 H4 histone acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010485 Catalysis of the reaction: acetyl-CoA + histone H4 = CoA + acetyl-histone H4. GO:0009497 obsolete 3Fe-4S/4Fe-4S electron transfer carrier biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009497 3Fe-4S/4Fe-4S electron transfer carrier OBSOLETE. (Was not defined before being made obsolete). GO:0034453 microtubule anchoring biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034453 Any process in which a microtubule is maintained in a specific location in a cell. GO:0010482 regulation of epidermal cell division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010482 regulation of hypodermal cell division Any process that modulates the frequency, rate or extent of the physical partitioning and separation of an epidermal cell into daughter cells. An epidermal cell is any of the cells that make up the epidermis. GO:0009498 obsolete bacterial-type ferredoxin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009498 bacterial-type ferredoxin OBSOLETE. (Was not defined before being made obsolete). GO:0010483 pollen tube reception biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010483 Interaction between the pollen tube, part of the male gametophyte, and the ovule, part of the female gametophyte, that results in the arrest of pollen tube growth, rupture of the pollen tube and the release of the sperm cells. GO:0034454 microtubule anchoring at centrosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034454 Any process in which a microtubule is maintained in a specific location in a cell by attachment to a centrosome. GO:0009499 obsolete monocluster bacterial-type ferredoxin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009499 monocluster bacterial-type ferredoxin OBSOLETE. (Was not defined before being made obsolete). GO:0010488 UDP-galactose:N-glycan beta-1,3-galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010488 Catalysis of the reaction: UDP-galactose + N-glycan = galactose-beta-1,3-N-glycan + UDP. GO:0034455 t-UTP complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034455 Nan1p-containing subcomplex of 90S preribosome A protein complex that forms a subcomplex of the 90S preribosome and is required for the subsequent assembly of the rest of the preribosome. In S. cerevisiae, it is composed of Utp5p, Utp4p, Nan1p, Utp8p, Utp9p, Utp10 and Utp15p. CHEBI:62803 fuel additive biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62803 GO:0010489 UDP-4-keto-6-deoxy-glucose-3,5-epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010489 Catalysis of the reaction: UDP-4-keto-6-deoxyglucose = UDP-4-keto-rhamnose. GO:0034456 UTP-C complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034456 Rrp7p-containing subcomplex of 90S preribosome A protein complex that forms a subcomplex of the 90S preribosome. In S. cerevisiae, it is composed of Rrp7p, Utp22p, Ckb1p, Cka1p, Ckb2p and Cka2p. GO:0034457 Mpp10 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034457 A protein complex that forms a subcomplex of the 90S preribosome. In S. cerevisiae, it is composed of Mpp10p, Imp3p and Imp4p. GO:0010486 manganese:proton antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010486 manganese:hydrogen antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Mn2+(in) + H+(out) = Mn2+(out) + H+(in). GO:0034458 3'-5' RNA helicase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034458 3' to 5' RNA helicase activity|ATP-dependent 3' to 5' RNA helicase activity|ATP-dependent 3'-5' RNA helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix in the direction 3' to 5'. GO:0010487 thermospermine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010487 RHEA:30515|MetaCyc:RXN-11190|EC:2.5.1.79 Catalysis of the reaction: S-adenosyl-L-methioninamine + spermidine = S-methyl-5'-thioadenosine + thermospermine + H+. CHEBI:62804 metallochlorin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62804 CHEBI:62805 isooctane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62805 GO:0010480 microsporocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010480 pollen mother cell differentiation The process aimed at the progression of a microsporocyte cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A microsporocyte is a diploid (2n) cell that undergoes meiosis and forms four haploid (1n) microspores; also called microspore mother cell and, in seed plants, pollen mother cell. GO:0010481 epidermal cell division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010481 hypodermal cell division Any process resulting in the physical partitioning and separation of an epidermal cell, any of the cells making up the epidermis, into daughter cells. GO:0034450 ubiquitin-ubiquitin ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034450 Reactome:R-HSA-937050|Reactome:R-HSA-975122 E4 Isoenergetic transfer of ubiquitin from one protein to an existing ubiquitin chain via the reaction X-ubiquitin + Y-ubiquitin -> Y-ubiquitin-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue. GO:0034448 EGO complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034448 GTPase-containing complex for Gap1p sorting in the endosome|EGO-GSE complex|GSE complex A vacuolar membrane-associated protein complex that is required for activation of microautophagy during exit from rapamycin-induced growth arrest. In budding yeast, S. cerevisiae, this complex includes Gtr1p, Gtr2p, Meh1p, and Slm4p. GO:0034449 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0034449 GO:0010495 long-distance posttranscriptional gene silencing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010495 long-distance propagation of posttranscriptional gene silencing A posttranscriptional gene silencing process in which the silencing signal originates in a tissue separate from the tissue in which the silencing takes place. GO:0034440 lipid oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034440 The removal of one or more electrons from a lipid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen. GO:0010496 intercellular transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010496 single organism intercellular transport|single-organism intercellular transport The movement of substances between cells. GO:0034441 plasma lipoprotein particle oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034441 plasma lipoprotein oxidation The modification of a lipid or protein within a plasma lipoprotein particle by oxidation of the lipid or one or more amino acids. GO:0010493 Lewis a epitope biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010493 LE A biosynthetic process The chemical reactions and pathways resulting in the formation of a Lewis a epitope, a trisaccharide (Fuc-alpha-(1->4)[Gal-beta-(1->3)]GlcNAc) characteristic of plant protein N-linked oligosaccharides. GO:0034442 regulation of lipoprotein oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034442 Any process that modulates the frequency, rate or extent of lipoprotein oxidation. GO:0034443 negative regulation of lipoprotein oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034443 inhibition of lipoprotein oxidation Any process that stops, prevents, or reduces the frequency, rate or extent of lipoprotein oxidation. GO:0010494 cytoplasmic stress granule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0010494 Wikipedia:Stress_granule cytoplasmic mRNP granule|stress granule A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress. GO:0034444 regulation of plasma lipoprotein oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034444 regulation of plasma lipoprotein particle oxidation Any process that modulates the frequency, rate or extent of lipoprotein oxidation, occurring in the blood plasma. GO:0010499 proteasomal ubiquitin-independent protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010499 The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome but do not involve ubiquitin. GO:0034445 negative regulation of plasma lipoprotein oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034445 inhibition of plasma lipoprotein oxidation|negative regulation of plasma lipoprotein particle oxidation Any process that stops, prevents, or reduces the frequency, rate or extent of lipoprotein particle oxidation, occurring in the blood plasma. CHEBI:62814 heme d cis-diol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62814 GO:0034446 substrate adhesion-dependent cell spreading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034446 cell spreading during cell substrate adhesion|substrate adhesion dependent cell spreading The morphogenetic process that results in flattening of a cell as a consequence of its adhesion to a substrate. GO:0010497 plasmodesmata-mediated intercellular transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010497 plasmodesmata-mediated cell-to-cell transport|plasmodesma-mediated intercellular transport|plasmodesma-mediated cell-to-cell transport|single-organism plasmodesmata-mediated intercellular transport|single organism plasmodesmata-mediated intercellular transport The movement of substances between cells via plasmodesmata. Plasmodesmata is a fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell. CHEBI:62811 heme d cis-diol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62811 GO:0034447 very-low-density lipoprotein particle clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034447 VLDL clearance The process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. GO:0010498 proteasomal protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010498 proteasome-mediated protein catabolism|proteasome-mediated protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome. GO:0010491 UTP:arabinose-1-phosphate uridylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010491 Catalysis of the reaction: alpha-L-arabinose 1-phosphate + UTP = UDP-L-arabinose + diphosphate. GO:0010492 maintenance of shoot apical meristem identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010492 The process in which an organism retains a population of shoot apical meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate. GO:0010490 UDP-4-keto-rhamnose-4-keto-reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010490 Catalysis of the reaction: UDP-4-keto-rhamnose + NADPH = UDP-rhamnose + NADP+. GO:0034437 obsolete glycoprotein transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034437 glycoprotein transporter activity OBSOLETE. Enables the transfer of a glycoprotein from one side of a membrane to the other. GO:0034438 lipoprotein amino acid oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034438 The modification of a lipoprotein by oxidation of one or more amino acids in the protein. GO:0034439 lipoprotein lipid oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034439 The modification of a lipoprotein by oxidation of the lipid group. GO:0010468 regulation of gene expression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010468 Wikipedia:Regulation_of_gene_expression regulation of protein expression|regulation of gene product expression Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form. GO:0010469 regulation of signaling receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010469 regulation of signalling receptor activity|regulation of receptor activity Any process that modulates the frequency, rate or extent of a signaling receptor activity. Receptor activity is when a molecule combines with an extracellular or intracellular messenger to initiate a change in cell activity. GO:0009480 obsolete class IIb cytochrome c biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009480 class IIb cytochrome c OBSOLETE. (Was not defined before being made obsolete). GO:0009481 obsolete aa3-type cytochrome c oxidase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009481 aa3-type cytochrome c oxidase OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 4 ferrocytochrome c + O2 = 4 ferricytochrome c + 2 H2O. GO:0009482 obsolete ba3-type cytochrome c oxidase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009482 ba3-type cytochrome c oxidase OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 4 ferrocytochrome c + O2 = 4 ferricytochrome c + 2 H2O. GO:0009483 obsolete caa3-type cytochrome c oxidase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009483 caa3-type cytochrome c oxidase OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 4 ferrocytochrome c + O2 = 4 ferricytochrome c + 2 H2O. GO:0010462 regulation of light-activated voltage-gated calcium channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010462 Any process that modulates the frequency, rate or extent of light-activated voltage-gated calcium channel activity. GO:0009473 obsolete cytochrome c7 (triheme) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009473 cytochrome c7 (triheme) OBSOLETE. (Was not defined before being made obsolete). GO:0010463 mesenchymal cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010463 The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. GO:0034430 monolayer-surrounded lipid storage body outer lipid monolayer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034430 oleosome outer lipid monolayer|lipid droplet outer lipid monolayer|oil body outer lipid monolayer|lipid storage body surface lipid monolayer|spherosome outer lipid monolayer The single layer of phopholipids surrounding a lipid storage body. GO:0009474 obsolete nonaheme cytochrome c biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009474 nonaheme cytochrome c OBSOLETE. (Was not defined before being made obsolete). GO:0034431 bis(5'-adenosyl)-hexaphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034431 AP6A hydrolase activity|diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase activity|AP-6-A hydrolase activity|AP(6)A hydrolase activity Catalysis of the reaction: P1-P6-bis(5'-adenosyl) hexaphosphate + H2O = AMP + adenosine 5'-pentaphosphate. GO:0009475 obsolete high-molecular-weight cytochrome c (hexadecaheme) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009475 high-molecular-weight cytochrome c (hexadecaheme) OBSOLETE. (Was not defined before being made obsolete). GO:0010460 positive regulation of heart rate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010460 Any process that activates or increases the frequency or rate of heart contraction. GO:0034432 bis(5'-adenosyl)-pentaphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034432 AP5A hydrolase activity|diadenosine 5',5'''-P1,P6-pentaphosphate hydrolase activity|AP-5-A hydrolase activity|Ap5a pyrophosphohydrolase activity|AP(5)A hydrolase activity Catalysis of the reaction: P1-P6-bis(5'-adenosyl) pentaphosphate + H2O = AMP + adenosine 5'-tetraphosphate. GO:0009476 obsolete class IV cytochrome c biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009476 class IV cytochrome c OBSOLETE. (Was not defined before being made obsolete). GO:0010461 light-activated ion channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010461 Enables the transmembrane transfer of an ion by a channel that opens in response to a light stimulus. GO:0009477 obsolete cytochrome c1 biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009477 cytochrome c1 OBSOLETE. A cytochrome c that is an integral component of the mitochondrial respiratory complex III. Functions as an electron donor to cytochrome c. GO:0010466 negative regulation of peptidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010466 Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide bonds within proteins. GO:0034433 steroid esterification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034433 A lipid modification process in which a steroid ester is formed by the combination of a carboxylic acid (often a fatty acid) and a steroid molecule (e.g. cholesterol). GO:0010467 gene expression biolink:BiologicalProcess go-plus goslim_flybase_ribbon http://purl.obolibrary.org/obo/GO_0010467 Wikipedia:Gene_expression The process in which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form. GO:0034434 sterol esterification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034434 A lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and a sterol molecule (e.g. cholesterol). GO:0009478 obsolete cytochrome c554 biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009478 cytochrome c554 OBSOLETE. (Was not defined before being made obsolete). GO:0010464 regulation of mesenchymal cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010464 Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. GO:0009479 obsolete cytochrome f biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009479 cytochrome f OBSOLETE. A cytochrome c that is characteristic of green plants and transfers electrons to plastocyanin. GO:0034435 cholesterol esterification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034435 A lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and cholesterol. In the blood this process is associated with the conversion of free cholesterol into cholesteryl ester, which is then sequestered into the core of a lipoprotein particle. GO:0010465 nerve growth factor receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010465 beta-nerve growth factor receptor activity|NGF receptor activity Combining with nerve growth factor (NGF), to prevent apoptosis in neurons and promote nerve growth, or to initiate a change in cell activity. GO:0034436 glycoprotein transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034436 The directed movement of a glycoprotein, any protein that contains covalently bound glycose (i.e. monosaccharide) residues, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0034426 etioplast membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034426 Either of the lipid bilayers that surround a etioplast and form the etioplast envelope. GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034427 3'-5' exonucleolytic nuclear-transcribed mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of the mRNA transcript body that occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction. GO:0034428 nuclear-transcribed mRNA catabolic process, exonucleolytic, 5'-3' biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034428 5'-3' exonucleolytic nuclear-transcribed mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of the mRNA transcript body that occurs when the 5' end is not protected by a 5'-cap; degradation proceeds in the 5' to 3' direction. GO:0010479 stele development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010479 The process whose specific outcome is the progression of the stele over time, from its formation to the mature structure. The stele is the central column of primary vascular tissue in the root and any tissue that it surrounds. GO:0009490 obsolete mononuclear iron electron carrier biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009490 mononuclear iron electron carrier OBSOLETE. A mononuclear iron entity that serves as an electron acceptor and electron donor in an electron transport system. GO:0034429 tectobulbar tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034429 Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the optic tectum towards target cells in the premotor reticulospinal system in the hindbrain. GO:0009491 obsolete redox-active disulfide bond electron carrier biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009491 redox-active disulphide bond electron carrier|redox-active disulfide bond electron carrier OBSOLETE. (Was not defined before being made obsolete). GO:0009492 obsolete 2Fe-2S electron transfer carrier biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009492 2Fe-2S electron transfer carrier OBSOLETE. (Was not defined before being made obsolete). GO:0009493 obsolete adrenodoxin-type ferredoxin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009493 adrenodoxin-type ferredoxin OBSOLETE. (Was not defined before being made obsolete). GO:0009494 obsolete chloroplast-type ferredoxin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009494 chloroplast-type ferredoxin OBSOLETE. (Was not defined before being made obsolete). GO:0010473 GDP-galactose:myoinositol-1-phosphate guanylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010473 Catalysis of the reaction: GDP-L-galactose + myo-inositol 1-phosphate = alpha-L-galactose-1-phosphate + GDP-myoinositol. GO:0009484 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009484 GO:0010474 glucose-1-phosphate guanylyltransferase (GDP) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010474 GDP:glucose-1-phosphate guanyltransferase activity Catalysis of the reaction: GDP + D-glucose 1-phosphate = phosphate + GDP-glucose. GO:0009485 obsolete cbb3-type cytochrome c oxidase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009485 cbb3-type cytochrome c oxidase OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 4 ferrocytochrome c + O2 = 4 ferricytochrome c + 2 H2O. GO:0034420 co-translational protein acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034420 co-translational protein amino acid acetylation|cotranslational protein amino acid acetylation The addition of an acetyl group to one or more amino acids in a protein, occurring before the protein has been completely translated and released from the ribosome. GO:0010471 GDP-galactose:mannose-1-phosphate guanylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010471 MetaCyc:RXN4FS-12 GDP-L-galactose:mannose-1-phosphate guanylyltransferase activity|GDP-L-galactose phosphorylase activity Catalysis of the reaction: GDP-L-galactose + alpha-D-mannose 1-phosphate = GDP-alpha-D-mannose + alpha-L-galactose-1-phosphate. GO:0009486 cytochrome bo3 ubiquinol oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009486 EC:1.10.3.-|MetaCyc:RXN0-5268|RHEA:30251 Catalysis of the reaction: 2 ubiquinol + O2 + 4 H+ = 2 ubiquinone + 2 H2O + 4 H+ [periplasmic space]. GO:0034421 post-translational protein acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034421 posttranslational protein amino acid acetylation|post-translational protein amino acid acetylation The addition of an acetyl group to one or more amino acids in a protein, occurring after the protein has been completely translated and released from the ribosome. GO:0009487 obsolete glutaredoxin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009487 glutaredoxin OBSOLETE. A small disulfide-containing redox protein that serves as a glutathione-disulfide oxidoreductase. CHEBI:62830 dTDP-4-dehydro-beta-L-rhamnose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62830 GO:0010472 GDP-galactose:glucose-1-phosphate guanylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010472 MetaCyc:RXN4FS-13 GDP-L-galactose:glucose-1-phosphate guanylyltransferase activity|GDP-L-galactose phosphorylase activity Catalysis of the reaction: GDP-L-galactose + alpha-D-glucose 1-phosphate = alpha-L-galactose-1-phosphate + GDP-alpha-D-glucose. GO:0009488 obsolete amicyanin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009488 amicyanin OBSOLETE. A copper-containing protein that acts as an electron carrier between methylamine dehydrogenase and cytochrome c. GO:0010477 response to sulfur dioxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010477 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sulfur dioxide (SO2) stimulus. GO:0034422 aleurone grain lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034422 The volume enclosed by the membrane of an aleurone grain. GO:0009489 obsolete rubredoxin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009489 rubredoxin OBSOLETE. A low molecular weight mononuclear iron protein involved in electron transfer, with an iron tetrahedrally coordinated by the sulfurs of four conserved cysteine residues. GO:0010478 chlororespiration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010478 A respiratory electron flow (from NAD(P)H to plastoquinone (PQ) and O2) involving both a nonphotochemical reduction and re-oxidation of PQ pool. CHEBI:62836 2-methylthio-N(6)-(cis-4-hydroxy-Delta(2)-isopentenyl)adenosine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62836 GO:0034423 autophagosome lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034423 autophagic vacuole lumen The volume enclosed within the autophagosome double-membrane. GO:0034424 Vps55/Vps68 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034424 A membrane-associated protein complex that is required for a late stage of endosomal transport. In budding yeast, this complex consists of Vps55p and Vps68p proteins. GO:0010475 galactose-1-phosphate guanylyltransferase (GDP) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010475 GDP:galactose-1-phosphate guanyltransferase activity Catalysis of the reaction: GDP + L-galactose 1-phosphate = phosphate + GDP-galactose. CHEBI:62833 1-myristoyl-sn-glycerol 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62833 GO:0010476 gibberellin mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010476 gibberellin-mediated signalling The series of molecular signals generated as a consequence of gibberellin stimulus. GO:0034425 etioplast envelope biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034425 The double lipid bilayer enclosing the etioplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space. CHEBI:62834 1-linoleoyl-sn-glycerol 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62834 CHEBI:62837 1-oleoyl-sn-glycerol 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62837 GO:0010470 regulation of gastrulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010470 Any process that modulates the rate or extent of gastrulation. Gastrulation is the complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. GO:0034415 tRNA 3'-trailer cleavage, exonucleolytic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034415 tRNA 3'-end cleavage, exonucleolytic|exonucleolytic tRNA 3'-trailer cleavage|exonucleolytic tRNA 3'-end cleavage Exonucleolytic cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA. GO:0010448 vegetative meristem growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010448 The increase in size or mass of a vegetative meristem, a population of undifferentiated cells in a plant shoot which maintains a continuous balance between the production of stem cells and the incorporation of their derivatives into lateral organ primordia. GO:0034416 bisphosphoglycerate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034416 diphosphoglycerate phosphatase activity|2,3-diphosphoglyceric acid phosphatase activity|glycerate-2,3-diphosphate phosphatase activity|2,3-bisphosphoglycerate phosphatase activity|2,3-diphosphoglycerate phosphatase activity Catalysis of the reaction: 2,3-diphosphoglycerate + H2O = phosphoglycerate + phosphate. GO:0010449 root meristem growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010449 The increase in size or mass of a root meristem, a population of undifferentiated cells in a plant root which maintains a continuous balance between the production of stem cells and the incorporation of their derivatives into the growth of the root. GO:0034417 bisphosphoglycerate 3-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034417 KEGG_REACTION:R09532|RHEA:27381|MetaCyc:RXN-11102|EC:3.1.3.80 2,3-bisphospho-D-glycerate 3-phosphohydrolase activity Catalysis of the reaction: 2,3-diphosphoglycerate + H2O = 2-phospho-D-glycerate + phosphate. GO:0010446 response to alkaline pH biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010446 response to basic pH|response to alkalinity Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH > 7. pH is a measure of the acidity or basicity of an aqueous solution. GO:0034418 urate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034418 urate formation|uric acid biosynthetic process|urate biosynthesis|urate synthesis|urate anabolism The chemical reactions and pathways resulting in the formation of urate, the anion of uric acid, 2,6,8-trioxypurine. GO:0010447 response to acidic pH biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010447 response to acidity Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution. GO:0034419 L-2-hydroxyglutarate oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034419 Catalysis of the reaction: L-2-hydroxyglutarate + O2 = 2-oxoglutarate + hydrogen peroxide. GO:0009460 obsolete cytochrome b biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009460 cytochrome b OBSOLETE. A cytochrome containing noncovalently bound protoheme (iron protoporphyrin IX; heme b). GO:0009461 obsolete cytochrome c biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009461 OBSOLETE. A cytochrome containing heme bound to the protein by one or, more (commonly two) thioether bonds involving sulfhydryl groups of cysteine residues. GO:0010440 stomatal lineage progression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010440 The process in which an unspecialized epidermal cell progresses through a series of divisions that culminate in the production of a stomatal complex. GO:0009451 RNA modification biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0009451 Wikipedia:RNA_editing RNA editing The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically. GO:0010441 guard cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010441 The process whose specific outcome is the progression of the guard cell over time, from its formation to the mature structure. GO:0009452 7-methylguanosine RNA capping biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009452 m(7)G RNA capping|RNA capping The sequence of enzymatic reactions by which the 5' cap structure, an inverted 7-methylguanosine linked via a 5'-5' triphosphate bridge (m7G(5')ppp(5')X) to the first transcribed residue, is added to a nascent transcript. GO:0009453 energy taxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009453 energytaxis|taxis in response to energy source The directed movement of a motile cell or organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates. CHEBI:62840 1-lauroyl-sn-glycerol 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62840 GO:0009454 aerotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009454 taxis in response to atmospheric oxygen The directed movement of a motile cell or organism in response to environmental oxygen. GO:0034410 cell wall beta-glucan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034410 cell wall beta-glucan anabolism|cell wall beta-glucan synthesis|cell wall beta-glucan formation|cell wall beta-glucan biosynthesis The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of cells. GO:0034411 cell wall (1->3)-beta-D-glucan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034411 cell wall 1,3-beta-glucan synthesis|cell wall 1,3-beta-glucan formation|cell wall 1,3-beta-glucan biosynthesis|cell wall beta-1,3-glucan biosynthesis|cell wall beta-1,3-glucan anabolism|cell wall beta-1,3-glucan biosynthetic process|cell wall 1,3-beta-glucan biosynthetic process|cell wall beta-1,3-glucan synthesis|cell wall beta-1,3-glucan formation|cell wall 1,3-beta-D-glucan biosynthetic process|cell wall 1,3-beta-glucan anabolism The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells. GO:0009455 redox taxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009455 taxis in response to redox stimulus|taxis in response to redox potential|redoxtaxis The directed movement of a motile cell or organism in response to redox potential. GO:0010444 guard mother cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010444 The process in which a meristemoid acquires the specialized features of a guard mother cell. CHEBI:62846 4-hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62846 GO:0010445 nuclear dicing body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0010445 D body A small round nuclear body, measuring 0.2-0.8 microns in diameter that is diffusely distributed throughout the nucleoplasm. Several proteins known to be involved in miRNA processing have been localized to these structures. D-bodies are thought to be involved in primary-miRNA processing and/or storage/assembly of miRNA processing complexes. GO:0034412 ascospore wall beta-glucan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034412 ascospore wall beta-glucan anabolism|ascospore wall beta-glucan synthesis|ascospore wall beta-glucan formation|ascospore wall beta-glucan biosynthesis The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores. CHEBI:62847 6alpha-hydroxy-17beta-estradiol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62847 GO:0009456 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009456 GO:0034413 ascospore wall (1->3)-beta-D-glucan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034413 ascospore wall 1,3-beta-glucan anabolism|ascospore wall 1,3-beta-glucan biosynthesis|ascospore wall 1,3-beta-glucan synthesis|ascospore wall 1,3-beta-glucan formation|ascospore wall beta-1,3-glucan biosynthesis|ascospore wall beta-1,3-glucan biosynthetic process|ascospore wall 1,3-beta-glucan biosynthetic process|ascospore wall beta-1,3-glucan anabolism|ascospore wall 1,3-beta-D-glucan biosynthetic process|ascospore wall beta-1,3-glucan synthesis|ascospore wall beta-1,3-glucan formation The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores. GO:0010442 guard cell morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010442 guard cell morphogenesis during differentiation Generation and organization of the polarized cell that is capable of turgor driven movement. GO:0009457 obsolete flavodoxin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009457 flavodoxin OBSOLETE. A group of small electron carriers, characteristic of anaerobic bacteria, photosynthetic bacteria, cyanobacteria and eukaryotic algae. Contain flavin mononucleotide. GO:0034414 tRNA 3'-trailer cleavage, endonucleolytic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034414 tRNA 3'-end cleavage, endonucleolytic|endonucleolytic tRNA 3'-trailer cleavage|endonucleolytic tRNA 3'-end cleavage Endonucleolytic cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA. GO:0009458 obsolete cytochrome biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009458 cytochrome OBSOLETE. A hemeprotein whose characteristic mode of action involves transfer of reducing equivalents associated with a reversible change in oxidation state of the prosthetic group. This redox change involves a single electron, reversible equilibrium between the Fe(II) and Fe(III) states of the central iron atom. GO:0010443 meristemoid mother cell division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010443 meristemoid division The asymmetric cell division by which a meristemoid mother cells (MMC) give rise to a meristemoid and another cell. The other cell may itself become a MMC or may generate an epidermal cell. Any cell that undergoes this type of division is a MMC. CHEBI:62845 4-hydroxy-17beta-estradiol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62845 CHEBI:47291 3-chloro-D-alanine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47291 GO:0009459 obsolete cytochrome a biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009459 cytochrome a OBSOLETE. A cytochrome containing heme a. CHEBI:144940 L-alanyl-AMP zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_144940 GO:0034404 nucleobase-containing small molecule biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034404 nucleobase, nucleoside and nucleotide biosynthesis|nucleobase, nucleoside and nucleotide anabolism|nucleobase, nucleoside and nucleotide synthesis|nucleobase, nucleoside and nucleotide formation The chemical reactions and pathways resulting in the formation of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide. GO:0010459 negative regulation of heart rate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010459 Any process that stops, prevents or reduces the frequency or rate of heart contraction. GO:0034405 response to fluid shear stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034405 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface. GO:0010457 centriole-centriole cohesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010457 The cell cycle process in which the two centrioles within a centrosome remain tightly paired. GO:0034406 cell wall beta-glucan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034406 cell wall beta-glucan metabolism The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of cells. GO:0034407 cell wall (1->3)-beta-D-glucan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034407 cell wall 1,3-beta-glucan metabolism|cell wall beta-1,3 glucan metabolic process|cell wall 1,3-beta-glucan metabolic process|cell wall 1,3-beta-D-glucan metabolic process|cell wall beta-1,3 glucan metabolism The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells. CHEBI:1617 4-hydroxy-3-octaprenylbenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_1617 GO:0010458 exit from mitosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010458 exit from mitotic division|mitotic exit The cell cycle transition where a cell leaves M phase and enters a new G1 phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place. GO:0034408 ascospore wall beta-glucan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034408 ascospore wall beta-glucan metabolism The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores. GO:0009470 obsolete class IIa cytochrome c biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009470 class IIa cytochrome c OBSOLETE. (Was not defined before being made obsolete). GO:0034409 ascospore wall (1->3)-beta-D-glucan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034409 ascospore wall 1,3-beta-D-glucan metabolic process|ascospore wall beta-1,3 glucan metabolic process|ascospore wall 1,3-beta-glucan metabolic process|ascospore wall beta-1,3 glucan metabolism|ascospore wall 1,3-beta-glucan metabolism The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores. GO:0009471 obsolete class III cytochrome c biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009471 class III cytochrome c OBSOLETE. (Was not defined before being made obsolete). GO:0009472 obsolete cytochrome c3 (tetraheme) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009472 cytochrome c3 (tetraheme) OBSOLETE. (Was not defined before being made obsolete). GO:0009462 obsolete cytochrome d biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009462 cytochrome d OBSOLETE. A cytochrome in which the prosthetic group is a tetrapyrrolic chelate of iron in which the degree of conjugation of double bonds is less than in porphyrin. This definition would appear to include siroheme proteins (e.g. nitrite and sulfite reductases), but these are not cytochromes. GO:0010451 floral meristem growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010451 The increase in size or mass of a floral meristem, a population of undifferentiated cells in a plant that gives rise to a flower. GO:0009463 obsolete cytochrome b/b6 biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009463 cytochrome b/b6 OBSOLETE. Diheme cytochrome b; cytochrome b has the hemes b(562) and b(566) and is a component of the mitochondrial respiratory chain complex III. Cytochrome b6 is a component of bc complex acting between photosystems II and I of photosynthesis. GO:0010452 histone H3-K36 methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010452 histone lysine H3 K36 methylation|histone H3 K36 methylation|histone H3K36me The modification of histone H3 by addition of one or more methyl groups to lysine at position 36 of the histone. GO:0009464 obsolete cytochrome b5 biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009464 cytochrome b5 OBSOLETE. (Was not defined before being made obsolete). GO:0009465 obsolete soluble cytochrome b562 biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009465 soluble cytochrome b562 OBSOLETE. (Was not defined before being made obsolete). GO:0010450 inflorescence meristem growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010450 The increase in size or mass of an inflorescence meristem, a population of undifferentiated cells in a plant shoot which produces small leaves and then floral meristems, which will give rise to flowers. GO:0034400 gerontoplast biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034400 A plastid found in senescing, formerly green tissues that is derived from a chloroplast that undergoes an organized developmental program of senescence. GO:0010455 positive regulation of cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010455 Any process that activates, maintains or increases the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. GO:0009466 obsolete class I cytochrome c biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009466 class I cytochrome c OBSOLETE. (Was not defined before being made obsolete). CHEBI:62857 alpha-L-Fucp-(1->2)-D-Galp biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62857 GO:0034401 chromatin organization involved in regulation of transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034401 stimulation of global transcription from RNA polymerase II promoter by histone modification|regulation of transcription from RNA polymerase II promoter, global by histone modification|activation of global transcription from RNA polymerase II promoter by histone modification|activation of transcription from RNA polymerase II promoter by histone modification|positive regulation of global transcription from Pol II promoter by histone modification|stimulation of transcription from RNA polymerase II promoter by histone modification|positive regulation of transcription from RNA polymerase II promoter, global by histone modification|regulation of transcription from RNA polymerase II promoter by histone modification|up-regulation of transcription from RNA polymerase II promoter by histone modification|up regulation of global transcription from RNA polymerase II promoter by histone modification|positive regulation of transcription from Pol II promoter by histone modification|regulation of gene-specific transcription from RNA polymerase II promoter by histone modification|positive regulation of transcription from RNA polymerase II promoter by histone modification|upregulation of transcription from RNA polymerase II promoter by histone modification|upregulation of global transcription from RNA polymerase II promoter by histone modification|positive regulation of gene-specific transcription from RNA polymerase II promoter by histone modification|regulation of transcription from Pol II promoter by histone modification|regulation of transcription by chromatin organisation|up regulation of transcription from RNA polymerase II promoter by histone modification|up-regulation of global transcription from RNA polymerase II promoter by histone modification|establishment or maintenance of chromatin architecture during transcription|regulation of global transcription from Pol II promoter by histone modification|regulation of transcription by chromatin organization Any cellular process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin that modulates the rate, frequency or extent of DNA-dependent transcription. GO:0009467 obsolete monoheme class I cytochrome c biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009467 monoheme class I cytochrome c OBSOLETE. (Was not defined before being made obsolete). GO:0010456 cell proliferation in dorsal spinal cord biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010456 The multiplication or reproduction of cells, resulting in the expansion of the dorsal spinal cord cell population. CHEBI:62858 4,6-Me(COOH)C-beta-D-Man-(1->4)-beta-D-GlcA-(1->2)-alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-1-diphospho-ditrans,polycis-undecaprenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62858 GO:0010453 regulation of cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010453 Any process that modulates the frequency, rate or extent of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. GO:0009468 obsolete diheme class I cytochrome c biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009468 diheme class I cytochrome c OBSOLETE. (Was not defined before being made obsolete). GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034402 The process in which proteins required for 3'-end transcript processing become associated with the RNA polymerase II holoenzyme complex and the 3' end of a transcript. GO:0010454 negative regulation of cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010454 Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. GO:0009469 obsolete class II cytochrome c biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009469 class II cytochrome c OBSOLETE. (Was not defined before being made obsolete). GO:0034403 alignment of 3' and 5' splice sites of mRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034403 alignment of 3' and 5' splice sites of nuclear mRNA Recognition of both the 5' and 3'-splice sites and positioning them in the correct alignment with respect to each other so that the second catalytic step of nuclear mRNA splicing can occur. GO:0010426 DNA methylation on cytosine within a CHH sequence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010426 cytosine methylation within a CNN sequence|cytosine methylation within a CHH sequence|DNA methylation on cytosine within a CNN sequence The covalent transfer of a methyl group, to C-5 or N-4, of a cytosine located within an asymmetric CHH sequence in a DNA molecule. H stands for an adenine, cytosine, or thymine nucleotide. GO:0010427 abscisic acid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010427 abscisate binding|ABA binding Interacting selectively and non-covalently with abscisic acid, plant hormones that regulate aspects of plant growth. GO:0010424 DNA methylation on cytosine within a CG sequence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010424 cytosine methylation within a CG sequence The covalent transfer of a methyl group to C-5 or N-4 of a cytosine located within a CG sequence in a DNA molecule. GO:0010425 DNA methylation on cytosine within a CNG sequence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010425 cytosine methylation within a CNG sequence The covalent transfer of a methyl group, to C-5 or N-4, of a cytosine located within a CNG sequence in a DNA molecule. N stands for any nucleotide. CHEBI:62860 4,6-Me(COOH)C-beta-D-Man-(1->4)-beta-D-GlcA-(1->2)-alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-1-diphospho-ditrans,polycis-undecaprenol(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62860 GO:0010428 methyl-CpNpG binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010428 Interacting selectively and non-covalently with a methylated cytosine/unspecified/guanine trinucleotide. GO:0010429 methyl-CpNpN binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010429 Interacting selectively and non-covalently with a methylated cytosine/unspecified/unspecified trinucleotide. CHEBI:47266 hydrogen bromide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47266 GO:0009430 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009430 GO:0009431 bacterial-type flagellum basal body, MS ring biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009431 flagellin-based flagellum basal body, MS ring|flagellar basal body, mounting plate|flagellar basal body, MS ring One of the rings of the bacterial-type flagellar basal body; a double-flanged ring that anchors the basal body to the cytoplasmic membrane. GO:0009432 SOS response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009432 Wikipedia:SOS_response An error-prone process for repairing damaged microbial DNA. GO:0009433 bacterial-type flagellum basal body, C ring biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009433 flagellar basal body, C ring|flagellin-based flagellum basal body, C ring Cytoplasmic ring located at the base of the bacterial-type flagellar basal body; acts as a rotor; includes three switch proteins, which generate torque and can change their conformational state in a bimodal fashion, so that the motor direction can switch between clockwise and counterclockwise. GO:0010422 regulation of brassinosteroid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010422 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of brassinosteroids. CHEBI:62868 hepatoprotective agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62868 GO:0010423 negative regulation of brassinosteroid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010423 Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of brassinosteroids. GO:0009434 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009434 GO:0009435 NAD biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009435 reduced NAD biosynthesis|reduced NAD biosynthetic process|NAD biosynthesis|reduced nicotinamide adenine dinucleotide biosynthesis|reduced nicotinamide adenine dinucleotide biosynthetic process|nicotinamide adenine dinucleotide biosynthetic process|nicotinamide adenine dinucleotide biosynthesis|NADH biosynthetic process|NADH biosynthesis|NAD (oxidized) biosynthetic process|NAD (oxidized) biosynthesis|NAD anabolism|NAD (reduced) biosynthesis|NAD (reduced) biosynthetic process|oxidized NAD biosynthetic process|oxidized NAD biosynthesis|NAD synthesis|oxidized nicotinamide adenine dinucleotide biosynthesis|oxidized nicotinamide adenine dinucleotide biosynthetic process|NAD formation The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH. CHEBI:62866 2-methylthio-N(6)-(Delta(2)-isopentenyl)adenosine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62866 GO:0010420 3,4-dihydroxy-5-polyprenylbenzoic acid O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010420 MetaCyc:RXN-9281|RHEA:44452|EC:2.1.1.114 polyprenyldihydroxybenzoate methyltransferase activity Catalysis of the reaction: 3,4-dihydroxy-5-polyprenylbenzoic acid + S-adenosyl-L-methionine = 3-methoxy-4-hydroxy-5-polyprenylbenzoic acid + S-adenosyl-L-homocysteine + H+. GO:0010421 hydrogen peroxide-mediated programmed cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010421 programmed cell death in response to hydrogen peroxide Programmed cell death induced by hydrogen peroxide. Programmed cell death is the cell death resulting from activation of endogenous cellular processes. GO:0009436 glyoxylate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009436 MetaCyc:GLYOXDEG-PWY glyoxylate catabolism|glyoxylate degradation|glyoxylate breakdown The chemical reactions and pathways resulting in the breakdown of glyoxylate, the anion of glyoxylic acid, HOC-COOH. CHEBI:62867 soyasaponin III biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62867 GO:0009437 carnitine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009437 carnitine metabolism|vitamin Bt metabolism|vitamin Bt metabolic process The chemical reactions and pathways involving carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane. GO:0009438 methylglyoxal metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009438 MetaCyc:METHGLYUT-PWY methylglyoxal pathway|methylglyoxal bypass|methylglyoxal metabolism The chemical reactions and pathways involving methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid. GO:0009439 cyanate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009439 MetaCyc:CYANCAT-PWY cyanate metabolism The chemical reactions and pathways involving cyanate, NCO-, the anion of cyanic acid. GO:0010437 9,10 (9', 10')-carotenoid-cleaving dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010437 Catalysis of the oxidative cleavage of carotenoids at the (9, 10) and/or (9', 10') double bond. GO:0010438 cellular response to sulfur starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010438 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sulfur. GO:0010435 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010435 EC:6.2.1.-|MetaCyc:RXN-10695 OPC-8:0 CoA ligase activity|3-oxo-2-(2'-[Z]-pentenyl)cyclopentane-1-octanoate CoA ligase activity|3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid (OPC-8:0) CoA ligase activity Catalysis of the reaction: ATP + 3-oxo-2-(2'-pentenyl)-cyclopentane-1-octanoic acid + coenzyme A = AMP + diphosphate + 3-oxo-2-(2'-pentenyl)-cyclopentane-1-octanoyl-CoA + H+. 3-oxo-2-(2'-pentenyl)-cyclopentane-1-octanoic acid is also known as OPC-8:0. GO:0010436 carotenoid dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010436 carotenoid-cleaving dioxygenase Catalysis of the oxidative cleavage of carotenoids. CHEBI:62871 EC 4.3.1.24 (phenylalanine ammonia-lyase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62871 CHEBI:62872 EC 1.2.3.1 (aldehyde oxidase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62872 GO:0010439 regulation of glucosinolate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010439 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae. GO:0009450 gamma-aminobutyric acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009450 MetaCyc:4AMINOBUTMETAB-PWY GABA catabolism|GABA catabolic process|4-aminobutyrate catabolism|gamma-aminobutyric acid catabolism|4-aminobutanoate catabolic process|gamma-aminobutyric acid degradation|4-aminobutanoate catabolism|gamma-aminobutyric acid breakdown|4-aminobutyrate catabolic process The chemical reactions and pathways resulting in the breakdown of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms. CHEBI:62875 2-methylthio-N(6)-(Delta(2)-isopentenyl)adenosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62875 GO:0009440 cyanate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009440 cyanate catabolism|cyanate degradation|cyanate breakdown The chemical reactions and pathways resulting in the breakdown of cyanate, NCO-, the anion of cyanic acid. GO:0010430 fatty acid omega-oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010430 MetaCyc:PWY-2724 A fatty acid oxidation process in which the methyl group at the end of the fatty acid molecule (the omega carbon) is first oxidized to a hydroxyl group, then to an oxo group, and finally to a carboxyl group. The long chain dicarboxylates derived from omega-oxidation then enter the beta-oxidation pathway for further degradation. GO:0009441 glycolate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009441 MetaCyc:GLYCOLATEMET-PWY glycolate metabolism The chemical reactions and pathways involving glycolate, the anion of hydroxyethanoic acid (glycolic acid). GO:0009442 allantoin assimilation pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009442 MetaCyc:PWY0-41 allantoin catabolism via ureidoglycolate|allantoin degradation pathway|allantoin catabolic process via ureidoglycolate The pathways by which allantoin is processed and converted to ureidoglycolate, and then into metabolically useful substrates. E. coli are able to utilize allantoin as a sole nitrogen source under anaerobic conditions by converting it to ureidoglycolate; this may be further metabolized to produce glyoxylate and thence 3-phosphoglycerate, or alternatively oxidized to oxolureate, which can converted into oxamate and carbamoylphosphate. This may then be further metabolized to CO2, NH4+ and ATP. CHEBI:62873 odorant receptor agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62873 GO:0009443 pyridoxal 5'-phosphate salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009443 MetaCyc:PLPSAL-PWY pyridoxal 5' phosphate salvage Any process that generates pyridoxal 5'-phosphate, the active form of vitamin B6, from derivatives of it without de novo synthesis. CHEBI:62879 2-methylthio-N(6)-(cis-4-hydroxy-Delta(2)-isopentenyl)adenosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62879 GO:0009444 pyruvate oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009444 MetaCyc:PYRUVOX-PWY|Wikipedia:Pyruvate_decarboxylation The chemical reactions and pathways resulting in the conversion of pyruvate to acetylphosphate. GO:0010433 bract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010433 The process in which the anatomical structure of a bract are generated and organized. A bract is a leaf, usually different in form from the foliage leaves, subtending a flower or inflorescence. GO:0009445 putrescine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009445 putrescine metabolism The chemical reactions and pathways involving putrescine, 1,4-diaminobutane; putrescine can be formed by decarboxylation of ornithine and is the metabolic precursor of spermidine and spermine. GO:0010434 bract formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010434 The process that gives rise to a bract. This process pertains to the initial formation of a structure from unspecified parts. A bract is a leaf, usually different in form from the foliage leaves, subtending a flower or inflorescence. GO:0010431 seed maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010431 A process in seed development that occurs after embryogenesis by which a quiescent state is established in a seed. Seed maturation is characterized by storage compound accumulation, acquisition of desiccation tolerance, growth arrest and the entry into a dormancy period of variable length that is broken upon germination. CHEBI:62877 2-deoxy-D-ribofuranose 5-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62877 GO:0009446 putrescine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009446 putrescine anabolism|putrescine synthesis|putrescine formation|putrescine biosynthesis The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane; putrescine can be synthesized from arginine or ornithine and is the metabolic precursor of spermidine and spermine. GO:0009447 putrescine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009447 putrescine catabolism|putrescine degradation|putrescine breakdown The chemical reactions and pathways resulting in the breakdown of putrescine, 1,4-diaminobutane; putrescine is the metabolic precursor of spermidine and spermine. GO:0010432 bract development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010432 The process whose specific outcome is the progression of the bract over time, from its formation to the mature structure. A bract is a leaf, usually different in form from the foliage leaves, subtending a flower or inflorescence. GO:0009448 gamma-aminobutyric acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009448 4-aminobutyrate metabolism|gamma-aminobutyric acid metabolism|4-aminobutyrate metabolic process|4-aminobutanoate metabolism|GABA metabolic process|GABA metabolism|4-aminobutanoate metabolic process The chemical reactions and pathways involving gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms. GO:0009449 gamma-aminobutyric acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009449 gamma-aminobutyric acid biosynthesis|4-aminobutanoate biosynthesis|4-aminobutanoate biosynthetic process|gamma-aminobutyric acid anabolism|gamma-aminobutyric acid synthesis|GABA biosynthetic process|GABA biosynthesis|gamma-aminobutyric acid formation|4-aminobutyrate biosynthesis|4-aminobutyrate biosynthetic process The chemical reactions and pathways resulting in the formation of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms. GO:0034396 negative regulation of transcription from RNA polymerase II promoter in response to iron biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034396 inhibition of transcription from RNA polymerase II promoter in response to iron|negative regulation of transcription from Pol II promoter in response to iron|down regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of transcription from RNA polymerase II promoter in response to iron Any process that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter in response to an iron stimulus. GO:0034397 telomere localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034397 telomere localisation Any process in which a telomere is transported to, and/or maintained in, a specific location. GO:0034398 telomere tethering at nuclear periphery biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034398 The process in which a telomere is maintained in a specific location at the nuclear periphery. GO:0034399 nuclear periphery biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034399 The portion of the nuclear lumen proximal to the inner nuclear membrane. CHEBI:1624 3-oxo-5beta-steroid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_1624 GO:0034390 smooth muscle cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034390 smooth muscle cell programmed cell death by apoptosis|SMC apoptosis|apoptosis of smooth muscle cells|smooth muscle cell apoptosis|programmed cell death, smooth muscle cells|programmed cell death of smooth muscle cells by apoptosis Any apoptotic process in a smooth muscle cell. Smooth muscle consists of non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. GO:0034391 regulation of smooth muscle cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034391 regulation of smooth muscle cell apoptosis|regulation of SMC apoptosis Any process that modulates the frequency, rate, or extent of smooth muscle cell apoptotic process. GO:0034392 negative regulation of smooth muscle cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034392 inhibition of smooth muscle cell apoptosis|negative regulation of SMC apoptosis|negative regulation of smooth muscle cell apoptosis|down-regulation of smooth muscle cell apoptosis|downregulation of smooth muscle cell apoptosis|down regulation of smooth muscle cell apoptosis Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell apoptotic process. GO:0034393 positive regulation of smooth muscle cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034393 positive regulation of SMC apoptosis|upregulation of smooth muscle cell apoptosis|stimulation of smooth muscle cell apoptosis|up-regulation of smooth muscle cell apoptosis|activation of smooth muscle cell apoptosis|positive regulation of smooth muscle cell apoptosis|up regulation of smooth muscle cell apoptosis Any process that activates or increases the frequency, rate, or extent of smooth muscle cell apoptotic process. GO:0034394 protein localization to cell surface biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034394 protein localisation at cell surface|protein localization at cell surface A process in which a protein is transported to, or maintained in, a location within the external part of the cell wall and/or plasma membrane. GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034395 regulation of specific transcription from RNA polymerase II promoter in response to iron Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to an iron stimulus. GO:0034385 triglyceride-rich plasma lipoprotein particle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034385 triacylglycerol-rich lipoprotein particle|triglyceride-rich lipoprotein particle A plasma lipoprotein particle that has a hydrophobic core enriched in triglycerides surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins. Triglyceride-rich lipoprotein particles transport lipids, which are non-covalently associated with the particles, in the blood. GO:0034386 4-aminobutyrate:2-oxoglutarate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034386 MetaCyc:GABATRANSAM-RXN|EC:2.6.1.19 GABA-2-oxoglutarate transaminase activity|GABA-alpha-ketoglutarate transaminase activity|4-aminobutyrate-2-oxoglutarate transaminase activity|gamma-aminobutyrate:alpha-oxoglutarate aminotransferase activity|gamma-aminobutyric acid-2-oxoglutarate transaminase activity|4-aminobutyric acid 2-ketoglutaric acid aminotransferase activity|gamma-aminobutyrate-alpha-ketoglutarate transaminase activity|GABA-oxoglutarate aminotransferase activity|GABA-2-oxoglutarate aminotransferase activity|GABA-alpha-ketoglutaric acid transaminase activity|GABA-alpha-ketoglutarate aminotransferase activity|4-aminobutyrate-2-oxoglutarate aminotransferase activity|4-aminobutanoate:2-oxoglutarate aminotransferase activity|gamma-aminobutyric acid-alpha-ketoglutaric acid aminotransferase activity|gamma-aminobutyric acid-alpha-ketoglutarate transaminase activity|4-aminobutyrate-2-ketoglutarate aminotransferase activity|gamma-aminobutyrate-alpha-ketoglutarate aminotransferase activity|GABA-oxoglutarate transaminase activity|GABA-alpha-oxoglutarate aminotransferase activity Catalysis of the reaction: 4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate. GO:0034387 4-aminobutyrate:pyruvate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034387 EC:2.6.1.96|RHEA:32263|MetaCyc:RXN-6902 gamma-aminobutyric acid pyruvate transaminase activity Catalysis of the reaction: 4-aminobutanoate + pyruvate = succinate semialdehyde + alanine. GO:0034388 Pwp2p-containing subcomplex of 90S preribosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034388 25-30 S subcomplex of 90S preribosome|UTP-B complex A protein complex that forms a subcomplex of the 90S preribosome and can interact directly with the 5' External Transcribed Spacer (ETS) of the full length pre-rRNA transcript. In S. cerevisiae, it sediments at 25-30 S and is composed of Pwp2p, Dip2p, Utp21p, Utp13p, Utp18p, and Utp6p. GO:0034389 lipid droplet organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034389 lipid particle organisation|lipid particle organization and biogenesis|lipid body organization|lipid particle organization|adiposome organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lipid particle. GO:0034380 high-density lipoprotein particle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034380 HDL assembly The non-covalent aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle. GO:0034381 plasma lipoprotein particle clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034381 lipoprotein particle clearance The process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. GO:0034382 chylomicron remnant clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034382 The process in which a chylomicron remnant is removed from the blood via receptor-mediated endocytosis into liver cells and its constituent parts degraded. GO:0034383 low-density lipoprotein particle clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034383 LDL clearance The process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. GO:0034384 high-density lipoprotein particle clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034384 HDL clearance The process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. GO:0034374 low-density lipoprotein particle remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034374 LDL remodeling|small dense LDL formation|small dense low-density lipoprotein particle formation The acquisition, loss or modification of a protein or lipid within a low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL. GO:0034375 high-density lipoprotein particle remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034375 HDL remodeling The acquisition, loss or modification of a protein or lipid within a high-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL. GO:0034376 conversion of discoidal high-density lipoprotein particle to spherical high-density lipoprotein particle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034376 discoidal high-density lipoprotein remodeling|discoidal HDL remodeling|conversion of discoidal HDL to spherical HDL The process in which a discoidal high-density lipoprotein (HDL) particle acquires additional lipid or protein molecules, and cholesterol in the particle is converted to tightly bound cholesterol esters by the action of phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT), resulting in the formation of a spherical HDL particle. GO:0034377 plasma lipoprotein particle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034377 The non-covalent aggregation and arrangement of proteins and lipids to form a plasma lipoprotein particle. GO:0034378 chylomicron assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034378 The non-covalent aggregation and arrangement of proteins and lipids in the intestine to form a chylomicron. GO:0034379 very-low-density lipoprotein particle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034379 VLDL assembly The non-covalent aggregation and arrangement of proteins and lipids in the liver to form a very-low-density lipoprotein particle. GO:0034370 triglyceride-rich lipoprotein particle remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034370 triacylglycerol-rich lipoprotein particle remodeling The acquisition, loss or modification of a protein or lipid within a triglyceride-rich lipoprotein particle, including the hydrolysis of triglyceride by lipoprotein lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride from a triglyceride-rich lipoprotein particle. GO:0034371 chylomicron remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034371 chylomicron remnant formation The acquisition, loss or modification of a protein or lipid within a chylomicron, including the hydrolysis of triglyceride by lipoprotein lipase and the subsequent loss of free fatty acid. GO:0034372 very-low-density lipoprotein particle remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034372 IDL formation|intermediate-density lipoprotein particle formation|VLDL remodeling The acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid. GO:0034373 intermediate-density lipoprotein particle remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034373 LDL formation|low-density lipoprotein particle formation|IDL remodeling The acquisition, loss or modification of a protein or lipid within an intermediate-density lipoprotein particle. GO:0034363 intermediate-density lipoprotein particle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034363 IDL particle|intermediate-density lipoprotein complex|IDL complex A triglyceride-rich lipoprotein particle that typically contains APOB100, APOE and APOCs and has a density of 1.006-1.019 g/ml and a diameter of between 25-30 nm. IDL particles are found in blood and are formed by the delipidation of very-low-density lipoprotein particles (VLDL). IDL particles are removed from blood by the liver, following binding to the APOE receptor, or are converted to low-density lipoprotein (LDL). GO:0034364 high-density lipoprotein particle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034364 HDL particle|high-density lipoprotein class complex|HDL complex|HDL3|HDL2 A lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE; found in blood and carries lipids from body tissues to the liver as part of the reverse cholesterol transport process. GO:0034365 discoidal high-density lipoprotein particle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034365 nascent HDL|discoidal HDL|nascent high-density lipoprotein particle A newly formed high-density lipoprotein particle; consists of a phospholipid bilayer surrounded by two or more APOA1 molecules. The discoidal HDL particle is formed when lipid-free or lipid-poor APOA1 acquires phospholipids and unesterified cholesterol from either cell membranes or triglyceride-rich lipoproteins (undergoing lipolysis by lipoprotein lipase). GO:0034366 spherical high-density lipoprotein particle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034366 mature HDL|spherical HDL|mature high-density lipoprotein particle A mature high-density lipoprotein (HDL) particle, converted from discoidal HDL particles following the esterification of cholesterol in the particle by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT). GO:0034367 protein-containing complex remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034367 macromolecular complex remodeling The acquisition, loss, or modification of macromolecules within a complex, resulting in the alteration of an existing complex. GO:0034368 protein-lipid complex remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034368 The acquisition, loss or modification of a protein or lipid within a protein-lipid complex. GO:0034369 plasma lipoprotein particle remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034369 The acquisition, loss or modification of a protein or lipid within a plasma lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the esterification of cholesterol by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT). GO:0034360 chylomicron remnant biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034360 A lipoprotein particle that is derived from a mature chylomicron particle by the removal of triglycerides from the chylomicron core by lipoprotein lipase and the subsequent loss of surface components. It characteristically contains apolipoprotein E (APOE) and is cleared from the blood by the liver. GO:0034361 very-low-density lipoprotein particle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034361 very-low-density lipoprotein complex|VLDL complex|VLDL particle A triglyceride-rich lipoprotein particle that is typically composed of APOB100, APOE and APOCs and has a density of about 1.006 g/ml and a diameter of between 20-80 nm. It is found in blood and transports endogenous products (newly synthesized cholesterol and triglycerides) from the liver. GO:0034362 low-density lipoprotein particle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034362 LDL particle|low-density lipoprotein complex|LDL complex A lipoprotein particle, rich in cholesterol esters and low in triglycerides that is typically composed of APOB100 and APOE and has a density of 1.02-1.06 g/ml and a diameter of between 20-25 nm. LDL particles are formed from VLDL particles (via IDL) by the loss of triglyceride and gain of cholesterol ester. They transport endogenous cholesterol (and to some extent triglycerides) from peripheral tissues back to the liver. GO:0009396 folic acid-containing compound biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009396 folic acid and derivative biosynthesis|folic acid-containing compound biosynthesis|folic acid and derivative biosynthetic process|vitamin M and derivative biosynthetic process|vitamin M and derivative biosynthesis|folate-containing compound biosynthesis|folate-containing compound biosynthetic process|folate and derivative biosynthesis|folate and derivative biosynthetic process|folic acid-containing compound anabolism|folic acid-containing compound synthesis|vitamin B9 and derivative biosynthetic process|folic acid-containing compound formation|vitamin B9 and derivative biosynthesis The chemical reactions and pathways resulting in the formation of folic acid and its derivatives. GO:0034352 positive regulation of glial cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034352 positive regulation of glial cell apoptosis|up regulation of glial cell apoptosis|upregulation of glial cell apoptosis|stimulation of glial cell apoptosis|up-regulation of glial cell apoptosis|activation of glial cell apoptosis Any process that activates or increases the frequency, rate, or extent of glial cell apoptotic process. GO:0010385 double-stranded methylated DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010385 Interacting selectively and non-covalently with double-stranded methylated DNA. Methylation of cytosine or adenine in DNA is an important mechanism for establishing stable heritable epigenetic marks. GO:0009397 folic acid-containing compound catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009397 vitamin M and derivative catabolism|folate and derivative catabolic process|folate-containing compound catabolic process|folic acid-containing compound degradation|folic acid-containing compound breakdown|folate-containing compound catabolism|vitamin M and derivative catabolic process|folate and derivative catabolism|folic acid and derivative catabolic process|vitamin B9 and derivative catabolic process|vitamin B9 and derivative catabolism|folic acid and derivative catabolism|folic acid-containing compound catabolism The chemical reactions and pathways resulting in the breakdown of folic acid and its derivatives. GO:0010386 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010386 GO:0034353 RNA pyrophosphohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034353 Catalysis of the removal of a 5' terminal pyrophosphate from the 5'-triphosphate end of an RNA, leaving a 5'-monophosphate end. GO:0009398 FMN biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009398 FMN anabolism|FMN synthesis|FMN formation|FMN biosynthesis The chemical reactions and pathways resulting in the formation of FMN, the oxidized form of flavin mononucleotide (riboflavin 5'-(dihydrogen phosphate)), which acts as a coenzyme for a number of oxidative enzymes including NADH dehydrogenase. GO:0034354 'de novo' NAD biosynthetic process from tryptophan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034354 de novo NAD biosynthetic process from tryptophan The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH. GO:0010383 cell wall polysaccharide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010383 The chemical reactions and pathways involving cell wall polysaccharides. GO:0009399 nitrogen fixation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009399 MetaCyc:N2FIX-PWY|Wikipedia:Nitrogen_fixation The process in which nitrogen is taken from its relatively inert molecular form (N2) in the atmosphere and converted into nitrogen compounds useful for other chemical processes, such as ammonia, nitrate and nitrogen dioxide. GO:0034355 NAD salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034355 NAD salvage pathway Any process that generates nicotinamide adenine dinucleotide (NAD) from derivatives of it, without de novo synthesis; salvage is usually from the degradation products nicotinic acid (Na) and nicotinamide (Nam). GO:0010384 cell wall proteoglycan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010384 cell wall proteoglycan metabolism The chemical reactions and pathways involving cell wall peptidoglycan, a group of glycoproteins that consist of a core-protein backbone O-glycosylated by one or more complex carbohydrates. GO:0010389 regulation of G2/M transition of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010389 regulation of mitotic entry Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle. GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034356 nicotinamide riboside salvage pathway|NR salvage pathway The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD) from the vitamin precursor nicotinamide riboside. GO:0034357 photosynthetic membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034357 A membrane enriched in complexes formed of reaction centers, accessory pigments and electron carriers, in which photosynthetic reactions take place. GO:0034358 plasma lipoprotein particle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034358 A spherical particle with a hydrophobic core of triglycerides and/or cholesterol esters, surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins. Plasma lipoprotein particles transport lipids, which are non-covalently associated with the particles, in the blood or lymph. GO:0010387 COP9 signalosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010387 signalosome assembly The aggregation, arrangement and bonding together of a set of components to form a COP9 signalosome. GO:0034359 mature chylomicron biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034359 A chylomicron that contains apolipoprotein C2 (APOC2), a cofactor for lipoprotein lipase (LPL) activity, and has a mean diameter of 500 nm and density of 0.95g/ml. Mature chylomicron particles transport exogenous (dietary) lipids from the intestines to other body tissues, via the blood and lymph. GO:0010388 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010388 GO:0010381 peroxisome-chloroplast membrane tethering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010381 attachment of peroxisome to chloroplast The attachment of a peroxisome to a chloroplast via molecular tethers that physically bridge their respective membranes and attach them to each other. The tethering may facilitate exchange of metabolites between the organelles. GO:0010382 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010382 GO:0034350 regulation of glial cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034350 regulation of glial cell apoptosis Any process that modulates the frequency, rate, or extent of glial cell apoptotic process. GO:0010380 regulation of chlorophyll biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010380 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors. GO:0034351 negative regulation of glial cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034351 down-regulation of glial cell apoptosis|downregulation of glial cell apoptosis|down regulation of glial cell apoptosis|inhibition of glial cell apoptosis|negative regulation of glial cell apoptosis Any process that stops, prevents, or reduces the frequency, rate, or extent of glial cell apoptotic process. GO:0034349 glial cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034349 apoptosis of glia|programmed cell death of glia by apoptosis|glia apoptosis|glial cell apoptosis|glial cell programmed cell death by apoptosis|apoptosis of glial cells|programmed cell death of glial cells by apoptosis|programmed cell death, glia|programmed cell death, glial cells|glia programmed cell death by apoptosis Any apoptotic process in a glial cell, a non-neuronal cell of the nervous system. GO:0034341 response to interferon-gamma biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034341 response to immune interferon|response to type II interferon|response to type II IFN|response to gamma-interferon Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon-gamma is also known as type II interferon. GO:0010396 rhamnogalacturonan II metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010396 rhamnogalacturonan II metabolism The chemical reactions and pathways involving rhamnogalacturonan II, a low molecular mass (5-10KDa) pectic polysaccharide. The backbone of RG-II contains at least 8 1,4-linked alpha-D-GalpA residues. GO:0034342 response to type III interferon biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034342 response to type III IFN|response to interferon-lambda Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type III interferon stimulus. Interferon lambda is the only member of the type III interferon found so far. GO:0010397 apiogalacturonan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010397 apiogalacturonan metabolism The chemical reactions and pathways involving the pectic apiogalacturonan, characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues substituted with apiose and apiobiose (D-apiofuranosyl-beta-(1->3)-D-apiose) side chains via O-2 or O-3 links. GO:0034343 type III interferon production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034343 type III interferon secretion|type III IFN production The appearance of type III interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon lambda is the only member of the type III interferon found so far. GO:0010394 homogalacturonan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010394 homogalacturonan metabolism The chemical reactions and pathways involving homogalacturonan, a pectin characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3. GO:0034344 regulation of type III interferon production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034344 regulation of type III IFN production Any process that modulates the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far. GO:0010395 rhamnogalacturonan I metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010395 rhamnogalacturonan I metabolism|RGI metabolism The chemical reactions and pathways involving rhamnogalacturonan I (RGI), a branched pectin with a backbone of alternating alpha-(1->2)-linked rhamnose and alpha-(1->4)-linked D-galacturonic acid residues that carries neutral side-chains of predominantly beta-(1->4)-D-galactose and/or alpha-(1->5)-L-arabinose residues attached to the rhamnose residues of the RGI backbone. GO:0034345 negative regulation of type III interferon production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034345 downregulation of type III interferon production|down regulation of type III interferon production|inhibition of type III interferon production|negative regulation of type III IFN production|down-regulation of type III interferon production Any process that stops, prevents, or reduces the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far. GO:0034346 positive regulation of type III interferon production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034346 upregulation of type III interferon production|stimulation of type III interferon production|up-regulation of type III interferon production|activation of type III interferon production|positive regulation of type III IFN production|up regulation of type III interferon production Any process that activates or increases the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far. GO:0034347 type III interferon binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034347 interferon-lambda binding Interacting selectively and non-covalently with a type III interferon. Interferon lambda is the only member of the type III interferon found so far. GO:0010398 xylogalacturonan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010398 xylogalacturonan metabolism The chemical reactions and pathways involving xylogalacturonan, a pectin characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues substituted on C-3 with beta-D-xylopyranose residues. GO:0034348 type III interferon receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034348 interferon-lambda receptor activity Combining with a type III interferon and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Interferon lambda is the only member of the type III interferon found so far. GO:0010399 rhamnogalacturonan I backbone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010399 rhamnogalacturonan I backbone metabolism The chemical reactions and pathways involving the alternating alpha-(1->2)-linked rhamnose and alpha-(1->2)-linked B-galacturonic acid residues of the rhamnogalacturonan I backbone. GO:0010392 galactoglucomannan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010392 galactoglucomannan metabolism The chemical reactions and pathways involving galactoglucomannan, a polysaccharide composed of D-glucose, D-galactose and D-mannose. The mannose units form the backbone structure (a linear main chain) decorated with a mixture of D-glucose and D-galactose side-units. GO:0010393 galacturonan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010393 galacturonan metabolism The chemical reactions and pathways involving galacturonan, a pectin polymer containing a backbone of alpha-(1->4)-linked D-galacturonic acid residues. GO:0010390 histone monoubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010390 The modification of histones by addition of a single ubiquitin group. CHEBI:1670 3-ureidoisobutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_1670 GO:0010391 glucomannan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010391 glucomannan metabolism The chemical reactions and pathways involving glucomannan, a polysaccharide composed of D-glucose and D-mannose. The mannose units form the backbone structure (a linear main chain) with the D-glucose as single side-units. GO:0034340 response to type I interferon biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034340 response to type I IFN Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type I interferon stimulus. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. CHEBI:37839 heterocyclyl sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37839 CHEBI:37838 carboacyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37838 UBERON:0014463 cardiac ganglion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014463 cardiac ganglion of Wrisberg|ganglion of Wrisberg|ganglia cardiaca|Wrisberg ganglion|cardiac ganglia set|cardiac ganglia Any of the parasympathetic ganglia of the cardiac plexus between the arch of the aorta and the bifurcation of the pulmonary artery. UBERON:0014464 renal fat pad biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014464 perirenal fat pad Encapsulated adipose tissue associated with the kidney UBERON:0014466 subarachnoid fissure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014466 CHEBI:37830 pentane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37830 CHEBI:37835 alkatetraene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37835 CHEBI:13862 asparagusate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_13862 CHEBI:37834 (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37834 UBERON:0014450 pretectal nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014450 pretectal area nucleus|nucleus area pretectalis|pretectal nucleus|nucleus of the pretectal area|nucleus of pretectal area A neural nucleus of the pretectal area (between dorsal thalamus and optic tectum) that receives afferents primarily from the retina and the optic tectum and are involved in modulating motor behavior in response to visual input. UBERON:0014451 tongue taste bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014451 gustatory papillae taste bud|gustatory papilla taste bud A taste bud that is located on the tongue, situated on a gustatory papilla. CHEBI:23203 cholestenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23203 CHEBI:37848 plant hormone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37848 UBERON:0014452 gustatory epithelium of tongue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014452 lingual gustatory epithelium A gustatory epithelium that is part of a tongue. UBERON:0014453 gustatory epithelium of palate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014453 palatal gustatory epithelium A gustatory epithelium that is part of a roof of mouth. UBERON:0014454 visceral abdominal adipose tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014454 visceral fat|visceral adipose tissue|intra-abdominal adipose tissue|abdominal fat|organ fat|intra-abdominal fat Subcutaneous adipose tissue that is located in the peritoneal cavity. UBERON:0014455 subcutaneous abdominal adipose tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014455 abdominal subcutaneous adipose tissue|subcutaneous abdominal fat|subcutaneous fat of abdominal region Subcutaneous adipose tissue that is located in the abdominal region. CHEBI:37840 hydroxyflavone sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37840 CHEBI:37841 isoprenoid phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37841 CHEBI:37846 imidazo[1,2-a]pyrazine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37846 CHEBI:37847 imidazopyrazine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37847 CHEBI:13850 apoprotein biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_13850 CHEBI:37810 octadecatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37810 CHEBI:37814 dialkylglycerophosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37814 CHEBI:37812 dialkylglycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37812 CHEBI:37826 sulfuric acid derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37826 CHEBI:37827 thiosulfuric acid derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37827 OBO:chebi#has_functional_parent has functional parent biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/chebi#has_functional_parent CHEBI:37806 penicillanic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37806 CHEBI:37807 ethyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37807 CHEBI:37808 butane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37808 CHEBI:37809 trans-dec-3-enoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37809 UBERON:0014478 rib skeletal system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014478 set of all ribs|rib series|rib skeleton Subdivision of skeletal system that consists of all ribs and rib joints in an organism. In many vertebrates this consists of the combination of the rib cage and all rib joints, but some vertebrates have ribs outside the thoracic rib cage. UBERON:0014477 thoracic skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014477 skeleton of thorax|thoracic skeleton|thoracic part of axial skeleton Subdivision of skeletal system that consists of all skeletal elements in the thoracic region of the trunk. In most vertebrates this is the rib cage and sternum. CHEBI:23155 chlorophenylethylene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23155 CHEBI:23156 chlorophenylmethane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23156 GO:0010525 regulation of transposition, RNA-mediated biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010525 Any process that modulates the frequency, rate or extent of RNA-mediated transposition. RNA-mediated transposition is a type of transpositional recombination which occurs via an RNA intermediate. GO:0010526 negative regulation of transposition, RNA-mediated biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010526 Any process that decreases the frequency, rate or extent of RNA-mediated transposition. RNA-mediated transposition is a type of transpositional recombination which occurs via an RNA intermediate. CHEBI:23150 chlorophenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23150 GO:0010523 negative regulation of calcium ion transport into cytosol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010523 Any process that decreases the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components. GO:0010524 positive regulation of calcium ion transport into cytosol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010524 Any process that increases the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components. GO:0010529 negative regulation of transposition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010529 Any process that decreases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites. CHEBI:62761 tyrosine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62761 CHEBI:62762 (+)-2-epi-prezizaene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62762 CHEBI:23154 chlorophenylethane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23154 GO:0010527 positive regulation of transposition, RNA-mediated biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010527 Any process that increases the frequency, rate or extent of RNA-mediated transposition. RNA-mediated transposition is a type of transpositional recombination which occurs via an RNA intermediate. CHEBI:23151 chlorophenoxyacetate anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23151 CHEBI:23152 chlorophenoxyacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23152 GO:0010528 regulation of transposition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010528 Any process that modulates the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites. CHEBI:62760 (-)-beta-curcumene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62760 CHEBI:62765 beta-D-glucosyl crocetin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62765 CHEBI:37798 cyclic phosphorus acid anhydride biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37798 CHEBI:62766 beta-D-glucosyl crocetin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62766 GO:0009530 primary cell wall biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009530 A plant cell wall that is still able to expand, permitting cell growth. Primary cell walls contain more pectin than secondary walls and no lignin is present. GO:0009531 secondary cell wall biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009531 Wikipedia:Secondary_cell_wall A plant cell wall that is no longer able to expand and so does not permit growth. Secondary cell walls contain less pectin that primary cell walls. The secondary cell is mostly composed of cellulose and is strengthened with lignin. CHEBI:62764 reactive nitrogen species biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62764 GO:0010521 telomerase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010521 Stops, prevents or reduces the activity of a telomerase. Telomerase catalyzes the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes extension of the 3'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence. GO:0009532 plastid stroma biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009532 The proteinaceous ground substance of plastids. CHEBI:62769 beta-D-gentiobiosyl crocetin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62769 GO:0009533 chloroplast stromal thylakoid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009533 Unstacked thylakoids that connect the grana stacks through the stroma. GO:0010522 regulation of calcium ion transport into cytosol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010522 Any process that modulates the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components. GO:0009534 chloroplast thylakoid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009534 Sac-like membranous structures (cisternae) in a chloroplast combined into stacks (grana) and present singly in the stroma (stroma thylakoids or frets) as interconnections between grana. An example of this component is found in Arabidopsis thaliana. CHEBI:62767 crocetin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62767 GO:0009535 chloroplast thylakoid membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009535 The pigmented membrane of a chloroplast thylakoid. An example of this component is found in Arabidopsis thaliana. GO:0010520 regulation of reciprocal meiotic recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010520 Any process that modulates the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate. CHEBI:62768 bis(beta-D-glucosyl) crocetin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62768 GO:0009536 plastid biolink:CellularComponent go-plus goslim_chembl|goslim_plant|goslim_pir|goslim_generic http://purl.obolibrary.org/obo/GO_0009536 Wikipedia:Plastid Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid. GO:0009537 proplastid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009537 The precursor of other plastids. GO:0009538 photosystem I reaction center biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009538 photosystem I reaction centre A photochemical system containing P700, the chlorophyll a dimer that functions as a primary electron donor. Functioning as a light-dependent plastocyanin-ferredoxin oxidoreductase, it transfers electrons from plastocyanin to ferredoxin. GO:0009539 photosystem II reaction center biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009539 photosystem II reaction centre An integral membrane complex containing P680, the chlorophyll a molecule that functions as a primary electron donor. In the light, functioning as a water-plastoquinone oxidoreductase, it transfers electrons from water to plastoquinone. CHEBI:37794 aminosulfinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37794 CHEBI:37793 amino sulfonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37793 GO:0010536 positive regulation of activation of Janus kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010536 positive regulation of tyrosine phosphorylation of JAK2 protein|positive regulation of tyrosine phosphorylation of JAK1 protein|positive regulation of activation of JAK2 protein|positive regulation of activation of JAK protein|positive regulation of activation of JAK1 protein|positive regulation of activation of JAK2 kinase activity|positive regulation of activation of JAK1 kinase activity|positive regulation of tyrosine phosphorylation of JAK protein Any process that increases the frequency or rate of activation of JAK (Janus Activated Kinase) protein. The activation of JAK protein is the process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it. GO:0010537 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010537 GO:0010534 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010534 GO:0010535 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010535 GO:0010538 obsolete Hsp27 protein regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010538 Hsp27 protein regulator activity OBSOLETE. Modulates the activity of the Hsp27 molecular chaperone. CHEBI:23162 chloropropene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23162 CHEBI:62770 beta-D-gentiobiosyl crocetin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62770 GO:0010539 obsolete Hsp27 protein inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010539 Hsp27 protein inhibitor activity OBSOLETE. Stops, prevents or reduces the activity of the Hsp27 molecular chaperone. CHEBI:62771 beta-D-gentiobiosyl beta-D-glucosyl crocetin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62771 CHEBI:62776 (1->4)-beta-D-galactan biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62776 GO:0009540 zeaxanthin epoxidase [overall] activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009540 EC:1.14.13.90 zea-epoxidase activity|zeaxanthin,NAD(P)H:oxygen oxidoreductase activity Catalysis of the reactions: zeaxanthin + NAD(P)H + H+ + O2 = antheraxanthin + NAD(P)+ + H2O; and antheraxanthin + NAD(P)H + H+ + O2 = violaxanthin + NAD(P)+ + H2O. CHEBI:62777 maltotriulose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62777 GO:0009541 etioplast prolamellar body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009541 A three dimensional regular lattice found in etioplasts. It is composed of a continuous system of tubules but when exposed to light the symmetrical arrangement is rapidly lost as tubules become pinched off into two dimensional sections of lattice. These for perforated sheets of membrane that move apart, extend and increase, finally establishing the typical granal and intergranal lamellae of the mature chloroplast. GO:0009542 granum biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009542 Distinct stack of lamellae seen within chloroplasts. Grana contain the pigments, electron transfer compounds, and enzymes essential to the light-dependent reactions of photosynthesis. GO:0010532 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010532 GO:0009543 chloroplast thylakoid lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009543 The cavity enclosed within the chloroplast thylakoid membrane. An example of this component is found in Arabidopsis thaliana. GO:0010533 regulation of activation of Janus kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010533 regulation of activation of JAK protein|regulation of tyrosine phosphorylation of JAK2 protein|regulation of tyrosine phosphorylation of JAK protein|regulation of tyrosine phosphorylation of JAK1 protein|regulation of activation of JAK2 protein|regulation of activation of JAK1 protein|regulation of activation of JAK2 kinase activity|regulation of activation of JAK1 kinase activity Any process that modulates the frequency or rate of activation of JAK (Janus Activated Kinase) protein. The activation of JAK protein is the process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it. GO:0009544 chloroplast ATP synthase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009544 The protein complex that catalyzes the phosphorylation of ADP to ATP in chloroplasts. GO:0009545 elaioplast biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009545 Wikipedia:Elaioplast A leucoplast in which oil is stored. GO:0010530 positive regulation of transposition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010530 Any process that increases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites. GO:0009546 plasmodesmatal cytoplasmic sleeve biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009546 plasmodesmatal cytoplasmic annulus The space between the plasma membrane and the desmotubule of a plasmodesma. GO:0010531 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010531 GO:0009547 plastid ribosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009547 A ribosome contained within a plastid. GO:0009548 plasmodesmatal plasma membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009548 The portion of the plasma membrane surrounding a plasmodesma. GO:0009549 cellulose microfibril biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009549 A microfibril composed of cellulose arranged in orthogonal layers. Cellulose is a straight chain polysaccharide composed of B(14) linked glucose subunits. It is a major component of plant cell walls. Higher plant microfibrils are about 10nm in diameter and extremely long in relation to their width. The cellulose molecules are oriented parallel to the long axis of the microfibril in a paracrystalline array, which provides great tensile strength. The microfibrils are held in place by the wall matrix and their orientation is closely controlled by the cell. CHEBI:23135 chlorobenzophenone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23135 CHEBI:23136 chlorobenzoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23136 GO:0010509 polyamine homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010509 Any biological process involved in the maintenance of an internal steady state of a polyamine. CHEBI:23133 chlorobenzoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23133 CHEBI:23134 chlorobenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23134 CHEBI:23139 chlorocyclohexene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23139 CHEBI:23138 chlorocatechol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23138 GO:0010503 obsolete negative regulation of cell cycle arrest in response to nitrogen starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010503 OBSOLETE. Any process that stops, prevents or reduces the frequency or rate of cell cycle arrest in response to nitrogen starvation. GO:0010504 obsolete regulation of cell cycle arrest in response to nitrogen starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010504 OBSOLETE. Any process that modulates the frequency, rate or extent of cell cycle arrest in response to nitrogen starvation. CHEBI:62780 alpha-D-Glcp-(1->3)-alpha-D-Glcp-(1->3)-D-Glcp biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62780 GO:0010501 RNA secondary structure unwinding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010501 RNA duplex unwinding The process in which a secondary structure of RNA are broken or 'melted'. GO:0010502 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010502 GO:0010507 negative regulation of autophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010507 Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm. CHEBI:62783 beta-D-Xylp-(1->4)-beta-D-Xylp-(1->4)-D-Xylp biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62783 GO:0010508 positive regulation of autophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010508 Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm. CHEBI:23132 chlorobenzenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23132 GO:0010505 obsolete positive regulation of cell cycle arrest in response to nitrogen starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010505 OBSOLETE. Any process that increases the frequency or rate of cell cycle arrest in response to nitrogen starvation. CHEBI:62781 alpha-L-Araf-(1->5)-alpha-L-Araf-(1->5)-L-Araf biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62781 GO:0010506 regulation of autophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010506 Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm. CHEBI:23130 chloroaniline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23130 CHEBI:62787 1,5-dihydroflavin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62787 CHEBI:62788 3-nonaprenyl-4,5-dihydroxybenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62788 CHEBI:62785 beta-D-Manp-(1->4)-beta-D-Manp-(1->4)-D-Manp biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62785 GO:0009510 plasmodesmatal desmotubule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009510 desmotubule central rod A tightly wound cylinder of membrane that is located within the plasmodesmal pore and runs the length of the plasmodesma. The desmotubule likely provides a rigid stability to plasmodesmata and confers a fixed diameter and pore size to the plasmodesmal canal, and is linked to the endoplasmic reticulum in each of the adjacent cell. GO:0009511 plasmodesmatal endoplasmic reticulum biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009511 plasmodesmatal ER Endoplasmic reticulum found in plasmodesmata, junctions connecting the cytoplasm of adjacent plant cells. GO:0010500 transmitting tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010500 The process whose specific outcome is the progression of the transmitting tract over time, from its formation to the mature structure. The transmitting tissue is the tissue in the style of a carpel through which the pollen tube grows; it connects the stigma and the inside of ovary. GO:0009512 cytochrome b6f complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009512 Wikipedia:Cytochrome_b6f_complex cytochrome b6-f complex|cytochrome b6/f complex|cytochrome b(6)f complex|cyt b6f complex|cyt b6-f complex|cyt b6/f complex|cyt b(6)f complex Complex that transfers electrons from reduced plastoquinone to oxidized plastocyanin and translocates protons from the stroma to the lumen. The complex contains a core structure of three catalytic subunits: cytochrome b, the Rieske iron sulfur protein (ISP), and cytochrome f, which are arranged in an integral membrane-bound dimeric complex; additional subunits are present, and vary among different species. CHEBI:62789 3-nonaprenyl-4,5-dihydroxybenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62789 GO:0009513 etioplast biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009513 Wikipedia:Etioplast A plastid arrested in the development of chloroplasts from proplastids due to absence of light or low light conditions. GO:0009514 glyoxysome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009514 Wikipedia:Glyoxysome A specialized form of peroxisome that contains the enzymes of the glyoxylate pathway. The glyoxysome is found in some plant cells, notably the cells of germinating seeds. GO:0009515 granal stacked thylakoid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009515 chloroplast stacked thylakoid Appressed thylakoid membranes that are part of a granum (stacked regions). A characteristic of these appressed regions is the preferential localization of photosystem II. GO:0009516 leucoplast biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009516 Wikipedia:Leucoplast A colorless plastid involved in the synthesis of monoterpenes. GO:0009517 PSII associated light-harvesting complex II biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009517 LHCII Protein-pigment complex associated with photosystem II. GO:0009518 PSI associated light-harvesting complex I biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009518 LHCI Protein-pigment complex associated with photosystem I. CHEBI:37773 organic phosphoramidate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37773 GO:0009519 middle lamella biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009519 Wikipedia:Middle_lamella Layer of intercellular material, chiefly pectic substances, cementing together the primary walls of contiguous cells. CHEBI:23147 chlorohydroquinones biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23147 CHEBI:23148 chloromethanes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23148 CHEBI:62790 3-nonaprenyl-4-hydroxy-5-methoxybenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62790 GO:0010514 induction of conjugation with cellular fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010514 The process in which a cell initiates conjugation with cellular fusion. Conjugation with cellular fusion is the process that results in the union of cellular and genetic information from compatible mating types. CHEBI:62791 3-nonaprenyl-4-hydroxy-5-methoxybenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62791 GO:0010515 negative regulation of induction of conjugation with cellular fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010515 Any process that stops, prevents, or reduces the frequency or rate of initiation of conjugation with cellular fusion. GO:0010512 negative regulation of phosphatidylinositol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010512 Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol. GO:0010513 positive regulation of phosphatidylinositol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010513 Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol. GO:0010518 positive regulation of phospholipase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010518 Any process that increases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid. CHEBI:23142 chloroethenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23142 GO:0010519 negative regulation of phospholipase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010519 Any process that decreases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid. GO:0010516 negative regulation of cellular response to nitrogen starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010516 Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular response to nitrogen starvation. CHEBI:23140 chlorodienelactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23140 CHEBI:62793 3-decaprenyl-4,5-dihydroxybenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62793 GO:0010517 regulation of phospholipase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010517 Any process that modulates the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid. CHEBI:23141 chloroethanol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23141 CHEBI:37787 acyclic mixed acid anhydride biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37787 CHEBI:37788 O(4)-phospho-L-tyrosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37788 CHEBI:62796 3-decaprenyl-4-hydroxy-5-methoxybenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62796 CHEBI:37785 organosulfinate oxoanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37785 GO:0009520 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009520 CHEBI:37786 acyclic phosphorus acid anhydride biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37786 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010510 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate. GO:0009521 photosystem biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0009521 Wikipedia:Photosystem reaction centre|reaction center A complex located in a photosynthetic membrane that consists of a photoreaction center associated with accessory pigments and electron carriers. Examples of this component are found in Arabidopsis thaliana and in photosynthetic bacterial and archaeal species. GO:0010511 regulation of phosphatidylinositol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010511 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol. GO:0009522 photosystem I biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009522 A photosystem that contains an iron-sulfur reaction center associated with accessory pigments and electron carriers. In cyanobacteria and chloroplasts, photosystem I functions as a light-dependent plastocyanin-ferredoxin oxidoreductase, transferring electrons from plastocyanin to ferredoxin; in photosynthetic bacteria that have only a single type I photosystem, such as the green sulfur bacteria, electrons can go either to ferredoxin (Fd) -> NAD+ or to menaquinone (MK) -> Cytb/FeS -> Cytc555 -> photosystem I (cyclic photophosphorylation). GO:0009523 photosystem II biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009523 Wikipedia:Photosystem_II A photosystem that contains a pheophytin-quinone reaction center with associated accessory pigments and electron carriers. In cyanobacteria and chloroplasts, in the presence of light, PSII functions as a water-plastoquinone oxidoreductase, transferring electrons from water to plastoquinone, whereas other photosynthetic bacteria carry out anoxygenic photosynthesis and oxidize other compounds to re-reduce the photoreaction center. GO:0009524 phragmoplast biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009524 Wikipedia:Phragmoplast Fibrous structure (light microscope view) that arises between the daughter nuclei at telophase and within which the initial partition (cell plate), dividing the mother cell in two (cytokinesis), is formed. Appears at first as a spindle connected to the two nuclei, but later spreads laterally in the form of a ring. Consists of microtubules. GO:0009525 phragmosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009525 Wikipedia:Phragmosome A flattened membranous vesicle containing cell wall components. GO:0009526 plastid envelope biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009526 The double lipid bilayer enclosing a plastid and separating its contents from the rest of the cytoplasm; includes the intermembrane space. GO:0009527 plastid outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009527 The outer, i.e. cytoplasm-facing, lipid bilayer of the plastid envelope. GO:0009528 plastid inner membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009528 The inner, i.e. lumen-facing, lipid bilayer of the plastid envelope; also faces the plastid stroma. GO:0009529 plastid intermembrane space biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009529 plastid envelope lumen The region between the inner and outer lipid bilayers of the plastid envelope. CHEBI:37783 organosulfinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37783 CHEBI:37784 sulfinic acid derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37784 CHEBI:23114 chloride salt biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23114 CHEBI:23117 chlorine molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23117 CHEBI:23115 chlorohydrocarbon biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23115 CHEBI:23116 chlorine atom biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_23116 OBA:VT0015071 appendage morphology trait biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_VT0015071 morphology of appendage The morphology of a appendage. OBA:VT0015074 organ system trait biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_VT0015074 The quality when measured in anatomical system. UBERON:0014540 white matter lamina of cerebellum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014540 white lamina of cerebellum|laminae albae of cerebellar cortex|isthmus of the cingulate gyrus|laminae albae of cerebellar cortex|isthmus-2|isthmus gyri cinguli|lamina alba of cerebellar cortex|isthmus gyri cingulatus|white laminae of cerebellum|isthmus of gyrus fornicatus|isthmus cinguli The white laminae of cerebellum is subdivision of the cerebellar cortex comprised of myelinated axons lying deep to the granule cell layer of the cerebellar cortex. UBERON:0014541 thoracic division of spinal cord central canal biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014541 thoracic spinal cord central canal Part of spinal cord central canal contained in the thoracic spinal cord. It is continuous rostrally with the cervical spinal cord central canal and caudally with the lumbar spinal cord central canal. UBERON:0014542 cervical division of cord spinal central canal biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014542 cervical spinal cord central canal Part of central canal contained within the cervical spinal cord. It is continuous caudally with the thoracic spinal cord central canal and rostrally with the fourth ventricle of the brain via the obex CHEBI:37754 6-hydroxypseudooxynicotine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37754 CHEBI:37755 4-(methylamino)butyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37755 CHEBI:37753 pseudooxynicotine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37753 UBERON:0014538 subdivision of spinal cord central canal biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014538 regional part of spinal cord central canal A subdivision of the central canal of the spinal cord along its anterior-posterior axis. This is typically subdivided into cervical, thoracic, lumbar and sacral segments CHEBI:37757 iodoalkane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37757 CHEBI:37750 chlorine oxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37750 CHEBI:23123 chloroacetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_23123 CHEBI:23128 chloroalkane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23128 CHEBI:23129 chloroamino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23129 CHEBI:23127 chloroalanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23127 UBERON:0014530 white matter lamina of neuraxis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014530 neuraxis lamina|lamina of neuraxis UBERON:0014531 white matter lamina of diencephalon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014531 diencephalon lamina|lamina of diencephalon UBERON:0014532 white matter lamina of cerebral hemisphere biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014532 cerebral hemisphere lamina|lamina of cerebral hemisphere CHEBI:37763 elemental silicon biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37763 GO:0009500 obsolete dicluster bacterial-type ferredoxin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009500 dicluster bacterial-type ferredoxin OBSOLETE. (Was not defined before being made obsolete). GO:0009501 amyloplast biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009501 Wikipedia:Amyloplast A plastid whose main function is to synthesize and store starch. GO:0009502 obsolete photosynthetic electron transport chain biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009502 photosynthetic electron transport chain OBSOLETE. A series of membrane-linked oxidation-reduction reactions in which electrons are transferred from an initial electron donor through a series of intermediates to a final electron acceptor (usually oxygen). GO:0009503 thylakoid light-harvesting complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009503 A thylakoid membrane complex of chlorophylls a and b together with chlorophyll a-b binding proteins. In addition, LHCs contain a number of other proteins, the function of which is speculative, together with accessory pigments. The LHCs capture and transfer energy to photosystems I and II. An example of this is found in Arabidopsis thaliana. GO:0009504 cell plate biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009504 Wikipedia:Cell_plate The nascent cell membrane and cell wall structure that forms between two daughter nuclei near the center of a dividing plant cell. It develops at the equitorial region of the phragmoplast. It grows outwards to join with the lateral walls and form two daughter cells. GO:0009505 plant-type cell wall biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009505 plant cell wall|cellulose and pectin-containing cell wall A more or less rigid stucture lying outside the cell membrane of a cell and composed of cellulose and pectin and other organic and inorganic substances. GO:0009506 plasmodesma biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009506 Wikipedia:Plasmodesma plasmodesmata A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell. GO:0009507 chloroplast biolink:CellularComponent go-plus goslim_plant http://purl.obolibrary.org/obo/GO_0009507 Wikipedia:Chloroplast A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. GO:0009508 plastid chromosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009508 A circular DNA molecule containing plastid encoded genes. GO:0009509 chromoplast biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009509 Wikipedia:Chromoplast A plastid containing pigments other than chlorophyll, usually yellow and orange carotenoid pigments. CHEBI:37738 undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-L-lysyl-D-alanyl-D-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37738 CHEBI:37739 glycerophospholipid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37739 CHEBI:37733 EC 3.1.1.8 (cholinesterase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37733 CHEBI:37736 D-fructofuranose 1,6-bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37736 CHEBI:37737 5-phospho-beta-D-ribosylamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37737 CHEBI:37734 phosphoric ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37734 CHEBI:37735 phosphonic ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37735 CHEBI:23102 chitobiosyldiphosphodolichol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23102 CHEBI:23101 N,N'-diacetylchitobioses biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23101 CHEBI:37749 halogen oxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37749 CHEBI:37741 L-allopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37741 CHEBI:37742 allopyranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37742 CHEBI:37747 L-allose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37747 CHEBI:37748 aldehydo-allose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37748 CHEBI:13796 S-polyprenyl-L-cysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_13796 CHEBI:37746 aldehydo-L-allose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37746 CHEBI:13790 N-acetylarylamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_13790 CHEBI:13792 N-hydroxyarylamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_13792 CHEBI:37740 beta-L-allose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37740 GO:0034572 monodemethylisoproturon dimethylaminedehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034572 UM-BBD_reactionID:r0897|EC:1.5.99.- Catalysis of the reaction: monodemethylisoproturon + H2O = didemethylisoproturon + formaldehyde + 2 H+ + 2 e-. GO:0034573 didemethylisoproturon amidohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034573 UM-BBD_reactionID:r0898 Catalysis of the reaction: didemethylisoproturon + H2O = carbamic acid + 4-isopropylaniline. GO:0034574 didemethylisoproturon dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034574 UM-BBD_reactionID:r0899|EC:1.17.99.- Catalysis of the reaction: didemethylisoproturon + H2O = 4'-(2-hydroxyisopropyl)phenylurea + 2 H+ + 2 e-. GO:0034575 4-isopropylaniline dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034575 EC:1.17.99.-|UM-BBD_reactionID:r0901 Catalysis of the reaction: 4-isopropylaniline + H2O = 4'-(2-hydroxyisopropyl)phenylaniline + 2 H+ + 2 e-. GO:0034576 N-isopropylacetanilide amidohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034576 UM-BBD_reactionID:r0913 Catalysis of the reaction: N-isopropylacetanilide + OH- = N-isopropylaniline + acetate. GO:0034577 N-isopropylacetaniline monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034577 UM-BBD_reactionID:r0914|EC:1.14.15.- Catalysis of the reaction: N-isopropylacetanilide + 1/2 O2 = acetanilide + acetone. GO:0034578 limonene 8-hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034578 UM-BBD_reactionID:r0916 Catalysis of the reaction: limonene + H2O = alpha-terpineol. GO:0034579 (1-methylpentyl)succinate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034579 UM-BBD_reactionID:r0920 Catalysis of the reaction: fumarate + n-hexane = (1-methylpentyl)succinate. GO:0034570 hydroxymonomethylisoproturon dimethylaminedehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034570 EC:1.5.99.-|UM-BBD_reactionID:r0894 Catalysis of the reaction: hydroxymonodemethylisoproturon + H2O = formaldehyde + 4'-(2-hydroxyisopropyl)phenylurea + 2 H+ + 2 e-. GO:0034571 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034571 UM-BBD_reactionID:r0895 Catalysis of the reaction: 4'-(2-hydroxyisopropyl)phenylurea + H2O = 4'-(2-hydroxyisopropyl)phenylaniline + carbamic acid. GO:0034569 monodemethylisoproturon dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034569 EC:1.17.99.-|UM-BBD_reactionID:r0893 Catalysis of the reaction: monodemethylisoproturon + H2O = hydroxymonodemethylisoproturon + 2 H+ + 2 e-. GO:0034561 1,2-bis(4-hydroxyphenyl)-2-proponol dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034561 UM-BBD_reactionID:r0862 Catalysis of the reaction: 1,2-bis(4-hydroxyphenyl)-2-propanol = 4,4'-dihydroxy-alpha-methylstilbene + H2O. GO:0034562 2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034562 UM-BBD_reactionID:r0864 Catalysis of the reaction: 2,2-bis(4-hydroxyphenyl)-1-propanol + NADH + H+ + O2 = 2,3-bis(4-hydroxyphenyl)-1,2-propanediol + NAD+ + H2O. GO:0034563 2,3-bis(4-hydroxyphenyl)-1,2-propanediol dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034563 UM-BBD_reactionID:r0867 Catalysis of the reaction: 2,3-bis(4-hydroxyphenyl)-1,2-propanediol + O2 = 4-hydroxyphenacyl alcohol + 4-hydroxybenzoate + 2 H+ + 2 e-. GO:0034564 4,4'-dihydroxy-alpha-methylstilbene dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034564 UM-BBD_reactionID:r0866 Catalysis of the reaction: 4,4'-dihydroxy-alpha-methylstilbene + O2 = 4-hydroxybenzaldehyde + 4-hydroxyacetophenone + 2 H+ + 2 e-. GO:0034565 1-nitro-1,2-dihydro-1,3,5-triazine hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034565 EC:3.5.99.-|UM-BBD_reactionID:r0872 Catalysis of the reaction: 1-nitro-1,2-dihydro-1,3,5-triazine + 2 H2O = 1-nitro-1,3,5-triazinane-2,4-diol. GO:0034566 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0034566 GO:0034567 chromate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034567 EC:1.97.1.-|UM-BBD_reactionID:r0884 Catalysis of the reaction: chromate = chromium (III). GO:0034568 isoproturon dimethylaminedehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034568 EC:1.5.99.-|UM-BBD_reactionID:r0892 Catalysis of the reaction: isoproturon + H2O = formaldehyde + monodemethylisoproturon + 2 H+ + 2 e-. GO:0034560 bisphenol A hydroxylase A activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034560 EC:1.14.13.-|UM-BBD_reactionID:r0861 Catalysis of the reaction: bisphenol A + NADH + H+ + O2 = 2,2-bis(4-hydroxyphenyl)-1-propanol + NAD+ + H2O. GO:0034558 technetium (VII) reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034558 UM-BBD_reactionID:r0859 Catalysis of the reaction: pertechnetate ion + 3/2 H2 = technetium (IV) oxide + H2O + OH-. GO:0034559 bisphenol A hydroxylase B activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034559 UM-BBD_reactionID:r0860 Catalysis of the reaction: bisphenol A + NADH + H+ + O2 = 1,2-bis(4-hydroxyphenyl)-2-propanol + NAD+ + H2O. GO:0010589 leaf proximal/distal pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010589 The regionalization process within a leaf by which specific areas of cell differentiation are determined along a proximal/distal axis. GO:0034550 dimethylarsinate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034550 UM-BBD_reactionID:r0838|EC:1.97.1.- Catalysis of the reaction: dimethylarsinate + 3 H+ + 2 e- = dimethylarsinous acid + H2O. GO:0009594 detection of nutrient biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009594 detection of nutrients|perception of nutrients|nutrient sensing The series of events in which a nutrient stimulus is received by a cell and converted into a molecular signal. GO:0010583 response to cyclopentenone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010583 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclopentenone stimulus. Cyclopentenones are oxylipins derived from polyunsaturated fatty acids. They are structurally similar to jasmonic acid, but contain a reactive unsaturated carbonyl structure in the cyclo-ring. Cyclopentenones include phytoprostanes and 12-oxo-phytodienoic acid. GO:0034551 mitochondrial respiratory chain complex III assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034551 mitochondrial cytochrome bc(1) complex assembly The aggregation, arrangement and bonding together of a set of components to form the cytochrome bc(1) complex (also known as ubiquinol-cytochrome c reductase), in the mitochondrial inner membrane. GO:0009595 detection of biotic stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009595 perception of biotic stimulus The series of events in which a biotic stimulus, one caused or produced by a living organism, is received and converted into a molecular signal. GO:0010584 pollen exine formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010584 The formation of the pollen exine. The reticulate pollen wall pattern consists of two layers, exine and intine. GO:0010581 regulation of starch biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010581 An process which modulate the frequency, rate or extent of starch biosynthesis, the chemical reactions and pathways resulting in the formation of starch. GO:0034552 respiratory chain complex II assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034552 The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex II. GO:0009596 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009596 GO:0034553 mitochondrial respiratory chain complex II assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034553 The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex II, in the mitochondrial inner membrane. GO:0010582 floral meristem determinacy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010582 The process in which a floral meristem becomes determinate (i.e. ceases to produce lateral organs and may or may not terminally differentiate). GO:0009597 detection of virus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009597 perception of virus The series of events in which a stimulus from a virus is received and converted into a molecular signal. GO:0009598 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009598 GO:0010587 miRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010587 microRNA catabolic process The chemical reactions and pathways resulting in the breakdown of miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression. GO:0034554 3,3',5-tribromobisphenol A reductive dehalogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034554 EC:1.97.1.-|UM-BBD_reactionID:r0842 Catalysis of the reaction: 3,3',5-tribromobisphenol A + 2 H+ + 2 e- = 3,3'-dibromobisphenol A + HBr. GO:0009599 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009599 GO:0034555 3,3'-dibromobisphenol A reductive dehalogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034555 EC:1.97.1.-|UM-BBD_reactionID:r0844 Catalysis of the reaction: 3,3'-dibromobisphenol A + 2 H+ + 2 e- = 3-monobromobisphenol A + HBr. GO:0010588 cotyledon vascular tissue pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010588 Vascular tissue pattern formation as it occurs in the cotyledon of vascular plants. GO:0010585 glutamine secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010585 The controlled release of glutamine by a cell. GO:0034556 nitrobenzoate nitroreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034556 EC:1.7.1.-|UM-BBD_reactionID:r0849 Catalysis of the reaction: o-nitrobenzoate + NADPH + H+ = o-hydroxylaminobenzoate + NADP+. GO:0034557 2-hydroxylaminobenzoate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034557 UM-BBD_reactionID:r0850|MetaCyc:RXN-8848 o-hydroxylaminobenzoate nitroreductase activity Catalysis of the reaction: 2-hydroxylaminobenzoate + NAD(P)H = anthranilate + NAD(P)+ + H2O. GO:0010586 miRNA metabolic process biolink:BiologicalProcess go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0010586 microRNA metabolic process The chemical reactions and pathways involving miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression. GO:0010580 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010580 GO:0034547 N-cyclopropylmelamine deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034547 UM-BBD_reactionID:r0825|MetaCyc:RXN-8018 Catalysis of the reaction: cyromazine + H2O = N-cyclopropylammeline + NH3. GO:0034548 N-cyclopropylammeline deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034548 UM-BBD_reactionID:r0826|MetaCyc:RXN-8019 Catalysis of the reaction: N-cyclopropylammeline + H2O = N-cyclopropylammelide + NH3. GO:0034549 N-cyclopropylammelide alkylamino hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034549 UM-BBD_reactionID:r0827|MetaCyc:RXN-8020|KEGG_REACTION:R06972 Catalysis of the reaction: N-cyclopropylammelide + H2O = cyclopropylamine + cyanuric acid. GO:0010594 regulation of endothelial cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010594 Any process that modulates the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium. GO:0010595 positive regulation of endothelial cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010595 Any process that increases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium. GO:0034540 3-monobromobisphenol A reductive dehalogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034540 EC:1.97.1.-|UM-BBD_reactionID:r0824 Catalysis of the reaction: 3-monobromobisphenol A + 2 H+ + 2 e- = bisphenol A + HBr. GO:0034541 dimethylarsinite methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034541 UM-BBD_reactionID:r0806 Catalysis of the reaction: dimethylarsenous acid + R2S-CH3 = trimethylarsine oxide + R2SH. GO:0010592 positive regulation of lamellipodium assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010592 positive regulation of lamellipodium biogenesis Any process that increases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell. GO:0010593 negative regulation of lamellipodium assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010593 negative regulation of lamellipodium biogenesis Any process that decreases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell. GO:0034542 trimethylarsine oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034542 UM-BBD_reactionID:r0807|EC:1.97.1.- Catalysis of the reaction: trimethylarsine oxide + 2 H+ + 2 e- = trimethylarsine + H2O. GO:0034543 5-aminosalicylate dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034543 UM-BBD_reactionID:r0809|EC:1.13.11.- Catalysis of the reaction: 5-aminosalicylate + O2 = cis-4-amino-6-carboxy-2-oxo-hexa-3,5-dienoate. GO:0010598 NAD(P)H dehydrogenase complex (plastoquinone) biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0010598 Complex that possesses NAD(P)H dehydrogenase (plastoquinone) activity. The complex is one of the components of the electron transport chain. It is involved in electron transport from an unidentified electron donor, possibly NADH, NADPH or ferredoxin(Fd) to the plastoquinone pool. GO:0010599 production of lsiRNA involved in RNA interference biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010599 RNA interference, production of lsiRNA Cleavage of double-stranded RNA to form lsiRNA (long small interfering RNA), a class of siRNAs 30 to 40 nt in length. lsiRNAs are induced by pathogen infection or under specific growth conditions. GO:0034544 trans-ACOHDA hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034544 UM-BBD_reactionID:r0810|EC:3.5.99.- Catalysis of the reaction: trans-4-amino-6-carboxy-2-oxo-hexa-3,5-dienoate + H2O = fumarylpyruvate + NH3. GO:0010596 negative regulation of endothelial cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010596 Any process that decreases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium. GO:0034545 fumarylpyruvate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034545 UM-BBD_reactionID:r0811|EC:3.7.1.20|RHEA:26168 Catalysis of the reaction: fumarylpyruvate + H2O = fumarate + pyruvate + H+. GO:0034546 2,4-dichloroaniline reductive dehalogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034546 UM-BBD_reactionID:r0819|EC:1.97.1.- Catalysis of the reaction: 2,4-dichloroaniline + 2 H+ + 2 e- = 4-chloroaniline + HCl. GO:0010597 green leaf volatile biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010597 The chemical reactions and pathways resulting in the formation of volatile molecules emitted from green plants, such as hexenal, hexenol and hexenyl acetate, from linoleic acid or linolenic acid. GO:0010590 regulation of septum digestion after cytokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010590 regulation of cell separation after cytokinesis|regulation of cell separation following cytokinesis|regulation of mitotic cytokinetic cell separation Any process that modulates the rate, frequency or extent of the process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis. GO:0010591 regulation of lamellipodium assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010591 regulation of lamellipodium biogenesis Any process that modulates the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell. GO:0034536 2-hydroxy-8-methylchromene-2-carboxylate isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034536 EC:5.3.99.-|UM-BBD_reactionID:r0782 Catalysis of the reaction: 2-hydroxy-8-methylchromene-2-carboxylate = 2-hydroxy-3-methylbenzalpyruvate. GO:0010569 regulation of double-strand break repair via homologous recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010569 Any process that modulates the frequency, rate or extent of the error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. GO:0034537 2-hydroxy-3-methylbenzalpyruvate hydratase-aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034537 UM-BBD_reactionID:r0783|EC:4.1.2.- Catalysis of the reaction: 2-hydroxy-3-methylbenzalpyruvate + H2O = pyruvate + 3-methylsalicylaldehyde. GO:0034538 3-methylsalicylaldehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034538 UM-BBD_reactionID:r0784 Catalysis of the reaction: 3-methylsalicylaldehyde + NAD+ = 3-methylsalicylate + NADH + H+. GO:0010567 regulation of ketone catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010567 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a ketone, carried out by individual cells. GO:0010568 regulation of budding cell apical bud growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010568 Any process that modulates the frequency, rate or extent of growth at the tip of a bud, in a cell that reproduces by budding. GO:0034539 3,3',5,5'-tetrabromobisphenol A reductive dehalogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034539 UM-BBD_reactionID:r0821|EC:1.97.1.- Catalysis of the reaction: 3,3',5,5'-tetrabromobisphenol A + 2 H+ + 2 e- = 3,3',5-tribromobisphenol A + HBr. CHEBI:23197 cholestanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23197 GO:0009580 obsolete thylakoid (sensu Bacteria) biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009580 thylakoid (sensu Bacteria) OBSOLETE. (Was not defined before being made obsolete). GO:0009581 detection of external stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009581 perception of external stimulus The series of events in which an external stimulus is received by a cell and converted into a molecular signal. GO:0009582 detection of abiotic stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009582 perception of abiotic stimulus The series of events in which an (non-living) abiotic stimulus is received by a cell and converted into a molecular signal. GO:0010561 negative regulation of glycoprotein biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010561 Any process that decreases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. GO:0009572 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009572 GO:0009573 chloroplast ribulose bisphosphate carboxylase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009573 chloroplast RubisCO complex A complex, located in the chloroplast, containing either both large and small subunits or just small subunits which carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate. An example of this component is found in Arabidopsis thaliana. GO:0010562 positive regulation of phosphorus metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010562 Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus. GO:0009574 preprophase band biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009574 Wikipedia:Preprophase_band A dense band of microtubules, 1-3 pm wide, that appears just beneath the cell membrane before the start of cell division in the cells of higher plants. It precedes the onset of prophase and then disappears as mitosis begins, yet it somehow determines the plane of orientation of the new cell plate forming in late telophase and marks the zone of the parental cell wall where fusion with the growing cell plate ultimately occurs. GO:0034530 4-hydroxymethylsalicyaldehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034530 EC:1.2.1.-|UM-BBD_reactionID:r0767 Catalysis of the reaction: 4-hydroxymethylsalicylaldehyde + NAD+ + H2O = 4-hydroxymethylsalicylate + NADH + 2 H+. GO:0034531 2-hydroxy-4-hydroxymethylbenzalpyruvate hydratase-aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034531 UM-BBD_reactionID:r0766|EC:4.1.2.- Catalysis of the reaction: 2-hydroxy-4-hydroxymethylbenzalpyruvate + H2O = pyruvate + 4-hydroxymethylsalicylaldehyde. GO:0009575 chromoplast stroma biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009575 The space enclosed by the double membrane of a chromoplast but excluding the photosynthetic material. GO:0010560 positive regulation of glycoprotein biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010560 Any process that increases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. GO:0034532 2-hydroxy-7-hydroxymethylchromene-2-carboxylate isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034532 UM-BBD_reactionID:r0765|EC:5.3.99.- Catalysis of the reaction: 2-hydroxy-7-hydroxymethylchromene-2-carboxylate = 2-hydroxy-4-hydroxymethylbenzalpyruvate. GO:0009576 leucoplast stroma biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009576 The space enclosed by the double membrane of a leucoplast. GO:0010565 regulation of cellular ketone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010565 Any process that modulates the chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. GO:0009577 elaioplast stroma biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009577 The space enclosed by the double membrane of an elaioplast. GO:0034533 1,2-dihydroxy-7-hydroxymethylnaphthalene dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034533 UM-BBD_reactionID:r0764 Catalysis of the reaction: 1,2-dihydroxy-7-hydroxymethylnaphthalene + O2 = 2-hydroxy-7-hydroxymethylchromene-2-carboxylate. GO:0010566 regulation of ketone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010566 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a ketone, carried out by individual cells. GO:0034534 1-methylnaphthalene hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034534 EC:1.14.13.-|UM-BBD_reactionID:r0795 Catalysis of the reaction: 1-methylnaphthalene + NADH + H+ + O2 = 1-hydroxymethylnaphthalene + NAD+ + H2O. GO:0009578 etioplast stroma biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009578 The space enclosed by the double membrane of an etioplast but excluding the prothylakoid space. It contains the etioplast DNA. GO:0010563 negative regulation of phosphorus metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010563 Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus. GO:0009579 thylakoid biolink:CellularComponent go-plus goslim_plant|goslim_pir|goslim_metagenomics|goslim_generic|goslim_chembl http://purl.obolibrary.org/obo/GO_0009579 Wikipedia:Thylakoid photosynthetic membrane A membranous cellular structure that bears the photosynthetic pigments in plants, algae, and cyanobacteria. In cyanobacteria thylakoids are of various shapes and are attached to, or continuous with, the plasma membrane. In eukaryotes they are flattened, membrane-bounded disk-like structures located in the chloroplasts; in the chloroplasts of higher plants the thylakoids form dense stacks called grana. Isolated thylakoid preparations can carry out photosynthetic electron transport and the associated phosphorylation. GO:0010564 regulation of cell cycle process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010564 Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. GO:0034535 1,2-dihydroxy-8-methylnaphthalene dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034535 UM-BBD_reactionID:r0781 Catalysis of the reaction: 1,2-dihydroxy-8-methylnaphthalene + O2 = 2-hydroxy-8-methylchromene-2-carboxylate + H+. CHEBI:62729 3-(all-trans-polyprenyl)benzene-1,2-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62729 CHEBI:62727 molybdopterin adenine dinucleotide(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62727 CHEBI:62728 molybdopterin adenine dinucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62728 GO:0034525 1-naphthaldehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034525 UM-BBD_reactionID:r0787 Catalysis of the reaction: 1-naphthaldehyde + NAD+ + H2O = 1-naphthoic acid + NADH + H+. GO:0034526 2-methylnaphthalene hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034526 EC:1.14.13.-|UM-BBD_reactionID:r0788 Catalysis of the reaction: 2-methylnaphthalene + NADH + O2 + H+ = 2-hydroxymethylnaphthalene + NAD+ + H2O. GO:0034527 1,2-dihydroxy-8-carboxynaphthalene dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034527 UM-BBD_reactionID:r0790 Catalysis of the reaction: 1,2-dihydroxy-8-carboxynaphthalene + O2 = 2-carboxy-2-hydroxy-8-carboxychromene. GO:0010578 regulation of adenylate cyclase activity involved in G protein-coupled receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010578 regulation of adenylate cyclase activity involved in G-protein signaling pathway|regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway|regulation of adenylate cyclase activity involved in G-protein signalling Any process that modulates the frequency, rate or extent of adenylate cyclase (AC) activity that is an integral part of a G protein-coupled receptor signaling pathway. GO:0034528 2-carboxy-2-hydroxy-8-carboxychromene isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034528 EC:5.3.99.-|UM-BBD_reactionID:r0791 Catalysis of the reaction: 2-carboxy-2-hydroxy-8-carboxychromene = 2-hydroxy-3-carboxybenzalpyruvate. GO:0010579 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010579 GO:0034529 2-hydroxy-3-carboxy-benzalpyruvate hydratase-aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034529 EC:4.1.2.-|UM-BBD_reactionID:r0792 Catalysis of the reaction: 2-hydroxy-3-carboxybenzalpyruvate + H2O = 3-formylsalicylic acid + pyruvate. GO:0009590 detection of gravity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009590 perception of gravity The series of events in which a gravitational stimulus is received and converted into a molecular signal. GO:0009591 obsolete perception of mechanical stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009591 perception of mechanical stimulus OBSOLETE. The series of events by which a mechanical stimulus is received by a cell and converted into a molecular signal. GO:0009592 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009592 GO:0009593 detection of chemical stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009593 perception of chemical stimulus|detection of chemical substance|perception of chemical substance|chemoreception|chemoperception The series of events in which a chemical stimulus is received by a cell and converted into a molecular signal. GO:0010572 positive regulation of platelet activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010572 Any process that increases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. GO:0009583 detection of light stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009583 detection of light|perception of light The series of events in which a light stimulus (in the form of photons) is received and converted into a molecular signal. CHEBI:62732 aromatic ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62732 GO:0009584 detection of visible light biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009584 perception of visible light The series of events in which a visible light stimulus is received by a cell and converted into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm. GO:0010573 vascular endothelial growth factor production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010573 VEGF production The appearance of vascular endothelial growth factor production due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. CHEBI:62733 aromatic amide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62733 GO:0010570 regulation of filamentous growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010570 Any process that modulates the frequency, rate or extent of the process in which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape. GO:0009585 red, far-red light phototransduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009585 phytochrome signaling pathway|red-sensitive opsin The sequence of reactions within a cell required to convert absorbed photons from red or far-red light into a molecular signal; the red, far-red light range is defined as having a wavelength within the range 660-730 nm. GO:0034520 2-naphthaldehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034520 EC:1.2.1.-|UM-BBD_reactionID:r0772 Catalysis of the reaction: 2-naphthaldehyde + NAD+ + H2O = 2-naphthoate + NADH + H+. GO:0010571 positive regulation of nuclear cell cycle DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010571 positive regulation of DNA replication during S phase|positive regulation of DNA replication involved in S-phase|positive regulation of DNA replication involved in S phase Any process that activates or increases the frequency, rate or extent of The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle. CHEBI:62731 2-methoxy-6-(all-trans-polyprenyl)phenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62731 GO:0009586 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009586 GO:0009587 obsolete phototrophin mediated phototransduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009587 phototrophin mediated phototransduction OBSOLETE. (Was not defined before being made obsolete). GO:0034521 1-naphthoic acid dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034521 EC:1.14.12.-|UM-BBD_reactionID:r0773 Catalysis of the reaction: 1-naphthoic acid + NADH + O2 + H+ = cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene + NAD+. GO:0010576 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010576 CHEBI:62736 4,4'-diapophytoene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62736 GO:0009588 UV-A, blue light phototransduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009588 violet-sensitive opsin|blue-sensitive opsin|short-wave-sensitive opsin The sequence of reactions within a cell required to convert absorbed photons from UV-A or blue light into a molecular signal; the UV-A, blue light range is defined as having a wavelength within the range of 315 to 400 nm. GO:0034522 cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034522 UM-BBD_reactionID:r0774 Catalysis of the reaction: cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene = 1,2-dihydroxy-8-carboxynaphthalene + 2 H+ + 2 e-. GO:0010577 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010577 GO:0010574 regulation of vascular endothelial growth factor production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010574 Any process that modulates the frequency, rate, or extent of production of vascular endothelial growth factor. GO:0034523 3-formylsalicylate oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034523 UM-BBD_reactionID:r0777 Catalysis of the reaction: 3-formylsalicylic acid + O2 + H2O = 2-hydroxyisophthalic acid + hydrogen peroxide. GO:0009589 detection of UV biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009589 detection of UV light stimulus|detection of UV radiation stimulus|perception of UV|detection of ultraviolet light stimulus|detection of ultraviolet radiation stimulus The series of events in which an ultraviolet radiation (UV light) stimulus is received and converted into a molecular signal. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers. CHEBI:62734 2,7-dihydroxy-4'-methoxyisoflavanone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62734 GO:0010575 positive regulation of vascular endothelial growth factor production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010575 Any process that increases or activates the frequency, rate, or extent of production of vascular endothelial growth factor. GO:0034524 2-hydroxyisophthalate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034524 UM-BBD_reactionID:r0776 Catalysis of the reaction: 2-hydroxyisophthalic acid = salicylate + CO2. CHEBI:62735 lupan-3beta,20-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62735 CHEBI:62738 15-cis-4,4'-diapophytoene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62738 CHEBI:62739 4,4'-diapophytofluene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62739 CHEBI:23178 cholest-7-ene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_23178 GO:0010547 thylakoid membrane disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010547 thylakoid membrane degradation The controlled breakdown of the thylakoid membrane in the context of a normal process. GO:0034514 mitochondrial unfolded protein response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034514 mtUPR The series of molecular signals generated as a consequence of the presence of unfolded proteins in the mitochondrial matrix; results in transcriptional upregulation of nuclear genes encoding mitochondrial stress proteins. GO:0034515 proteasome storage granule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034515 PSG An aggregation of proteasome core protease (CP) and regulatory particle (RP) complexes that localizes in the cytoplasm as dot-like structures when cells are in a quiescent state. GO:0010548 regulation of thylakoid membrane disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010548 regulation of thylakoid membrane degradation Any process that modulates the frequency, rate or extent of thylakoid membrane disassembly. GO:0034516 response to vitamin B6 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034516 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B6 stimulus. Vitamin B6 encompasses pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate. GO:0010545 obsolete Hsp90 protein regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010545 Hsp90 protein regulator activity OBSOLETE. Binds to and modulates the activity of the molecular chaperone Hsp90. GO:0010546 obsolete Hsp90 protein inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010546 Hsp90 protein inhibitor activity OBSOLETE. Stops, prevents or reduces the activity of the Hsp90 molecular chaperone. GO:0034517 ribophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034517 The selective autophagy process in which cells degrade mature ribosomes under conditions of starvation. GO:0034518 RNA cap binding complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034518 Any protein complex that binds to a specialized RNA cap structure at any time in the lifetime of the RNA. GO:0034519 cytoplasmic RNA cap binding complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034519 A protein complex found in the cytoplasm that binds the 5' cap structure of an mRNA, and typically consists of the cap-binding protein eIF4E, the adaptor protein eIF4G, and a multi-factor complex comprising eIF1, eIF2, eIF3 and eIF5. This complex mediates recruitment of the 40S subunit to mRNA. CHEBI:62740 all-trans-4,4'-diapophytofluene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62740 GO:0010549 regulation of membrane disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010549 Any process that modulates the frequency, rate or extent of membrane disassembly. GO:0009560 embryo sac egg cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009560 female gamete generation|female gametophyte egg cell differentiation The process in which an uncellularized embryo sac nucleus cellularizes and acquires the specialized features of an egg cell. An example of this process is found in Arabidopsis thaliana. CHEBI:62743 4,4'-diaponeurosporene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62743 GO:0009550 primary plasmodesma biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009550 simple plasmodesma A plasmodesma that consists of a simple, single channel; found predominantly in young tissue and formed as a function of cell plate formation during cytokinesis. GO:0009551 secondary plasmodesma biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009551 A plasmodesma with a branched structure, often with many channels leading into a larger central cavity; found in older tissues and usually derived from preexisting primary plasmodesmata. GO:0010540 basipetal auxin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010540 The unidirectional movement of auxin from the apex to base of an organ, including the shoot, leaf, primary root, or lateral root. GO:0009552 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009552 CHEBI:62741 4,4'-diapo-zeta-carotene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62741 GO:0009553 embryo sac development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009553 female gametophyte development The process whose specific outcome is the progression of the embryo sac over time, from its formation to the mature structure. The process begins with the meiosis of the megasporocyte to form four haploid megaspores. Three of the megaspores disintegrate, and the fourth undergoes mitosis giving rise to a binucleate syncytial embryo sac. The two haploid nuclei migrate to the opposite poles of the embryo sac and then undergo two rounds of mitosis generating four haploid nuclei at each pole. One nucleus from each set of four migrates to the center of the cell. Cellularization occurs, resulting in an eight-nucleate seven-celled structure. This structure contains two synergid cells and an egg cell at the micropylar end, and three antipodal cells at the other end. A binucleate endosperm mother cell is formed at the center. The two polar nuclei fuse resulting in a mononucleate diploid endosperm mother cell. The three antipodal cells degenerate. CHEBI:62742 all-trans-4,4'-diapo-zeta-carotene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62742 GO:0009554 megasporogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009554 megaspore development|meiosis of the megasporocyte|megaspore mother cell meiosis|meiotic division of the megasporocyte The process in which the megasporocyte undergoes meiosis, giving rise to four haploid megaspores in the nucellus. GO:0034510 centromere separation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034510 The cell cycle process in which centromeres are physically detached from each other during chromosome separation. GO:0010543 regulation of platelet activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010543 Any process that modulates the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. CHEBI:62747 1-acyl-sn-glycero-3-phosphoglycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62747 GO:0009555 pollen development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009555 male gametophyte development|male gametophyte formation|microgametophyte development|formation of generative and vegetative cells|pollen grain formation The process whose specific outcome is the progression of the pollen grain over time, from its formation to the mature structure. The process begins with the meiosis of the microsporocyte to form four haploid microspores. The nucleus of each microspore then divides by mitosis to form a two-celled organism, the pollen grain, that contains a tube cell as well as a smaller generative cell. The pollen grain is surrounded by an elaborate cell wall. In some species, the generative cell immediately divides again to give a pair of sperm cells. In most flowering plants, however this division takes place later, in the tube that develops when a pollen grain germinates. GO:0034511 U3 snoRNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034511 Interacting selectively and non-covalently with U3 small nucleolar RNA. GO:0010544 negative regulation of platelet activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010544 Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. GO:0009556 microsporogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009556 microspore development The process in which the microsporocyte undergoes meiosis, giving rise to four haploid microspores. GO:0034512 box C/D RNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034512 box C/D sRNA binding|box C/D snoRNA binding Interacting selectively and non-covalently with box C/D small nucleolar RNA. CHEBI:62745 ammoniodiacetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62745 GO:0010541 acropetal auxin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010541 The unidirectional movement of auxin from the base towards the apex of an organ, including the shoot, leaf, primary root, or lateral root. GO:0009557 antipodal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009557 The process in which an uncellularized nucleus cellularizes and acquires the specialized features of an antipodal cell. GO:0010542 nitrate efflux transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010542 Enables the transfer of nitrate from the inside of the cell to the outside of the cell across a membrane. GO:0034513 box H/ACA snoRNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034513 Interacting selectively and non-covalently with box H/ACA small nucleolar RNA. CHEBI:62746 2-acyl-sn-glycero-3-phospho-D-myo-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62746 GO:0009558 embryo sac cellularization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009558 megagametophyte cellularization|female gametophyte cellularization|cellularization of the embryo sac The process in which the eight-nucleate single celled female gametophyte develops into the seven-celled female gametophyte. This mature structure contains two synergid cells and an egg cell at the micropylar end, and three antipodal cells at the other end. A binucleate endosperm mother cell is formed at the center. An example of this process is found in Arabidopsis thaliana. GO:0009559 embryo sac central cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009559 female gametophyte central cell differentiation|embryo sac endosperm mother cell differentiation The process in which the two uncellularized polar nuclei cellularize, fuse and acquire the specialized features of a mononucleate diploid central cell. CHEBI:62749 2-acylglycerophosphoinositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_62749 CHEBI:47136 pentachlorobenzene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47136 GO:0010558 negative regulation of macromolecule biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010558 Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. GO:0034503 protein localization to nucleolar rDNA repeats biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034503 protein localisation to nucleolar rDNA repeats|condensin localization to nucleolar rDNA repeats Any process in which a protein is transported to, or maintained at, the rDNA repeats on a chromosome in the nucleolus. GO:0034504 protein localization to nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034504 protein localization in cell nucleus|protein localization in nucleus|protein targeting to nucleus|protein localisation to nucleus A process in which a protein transports or maintains the localization of another protein to the nucleus. GO:0010559 regulation of glycoprotein biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010559 Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. GO:0010556 regulation of macromolecule biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010556 Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. GO:0034505 tooth mineralization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034505 tooth calcification The process in which calcium salts are deposited into calcareous tooth structures such as dental enamel, dentin and cementum. GO:0010557 positive regulation of macromolecule biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010557 Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. GO:0034506 chromosome, centromeric core domain biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034506 chromosome, centromeric core region|chromosome, centric core region The innermost portion of the centromeric region of a chromosome, encompassing the core region of a chromosome centromere and the proteins that bind to it. GO:0034507 chromosome, centromeric outer repeat region biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034507 chromosome, centric outer repeat region The portion of the centromeric region of a chromosome that flanks the core region, encompassing repeated regions of a chromosome centromere and the proteins that bind to it. GO:0034508 centromere complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034508 centromere assembly|chromosome, centromeric region assembly|centromere organization The aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex. Includes the formation of the chromatin structures which form a platform for the kinetochore, and assembly of the kinetochore onto this specialized chromatin. In fission yeast and higher eukaryotes this process also includes the formation of heterochromatin at the outer repeat (pericentric) regions of the centromere. GO:0009570 chloroplast stroma biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009570 The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis. GO:0034509 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0034509 CHEBI:47133 5'-chloro-5'-deoxyadenosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47133 GO:0009571 proplastid stroma biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009571 The space enclosed by the double membrane of a proplastid. GO:0010550 regulation of PSII associated light-harvesting complex II catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010550 regulation of LHCII degradation|regulation of LHCII catabolism Any process that modulates the chemical reactions and pathways resulting in the breakdown of one or more components of the light-harvesting complex of photosystem II. GO:0009561 megagametogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009561 Wikipedia:Megagametogenesis megagametophyte nucleus division|embryo sac development from the megaspore The process whose specific outcome is the progression of the embryo sac over time, from its formation as the megaspore to the mature structure. The process begins when three of the four haploid megaspores disintegrate, and the fourth undergoes mitosis giving rise to a binucleate syncytial embryo sac. The two haploid nuclei migrate to the opposite poles of the embryo sac and then undergo two rounds of mitosis generating four haploid nuclei at each pole. One nucleus from each set of four migrates to the center of the cell. Cellularization occurs, resulting in an eight-nucleate seven-celled structure. This structure contains two synergid cells and an egg cell at the micropylar end, and three antipodal cells at the other end. A binucleate endosperm mother cell is formed at the center. CHEBI:62755 alpha-bergamotene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62755 GO:0009562 embryo sac nuclear migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009562 megagametophyte nucleus migration|female gametophyte nucleus migration|megagametophyte nuclear migration|female gametophyte nuclear migration|embryo sac nucleus migration The directed movement of an embryo sac nucleus to the pole or center of the cell. GO:0010551 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010551 GO:0009563 synergid differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009563 synergid cell differentiation The process in which an uncellularized nucleus cellularizes and acquires the specialized features of a synergid cell. CHEBI:62753 alpha-longipinene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62753 GO:0009564 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009564 GO:0010554 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010554 GO:0009565 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009565 GO:0009566 fertilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009566 Wikipedia:Fertilisation syngamy The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy). GO:0010555 response to mannitol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010555 response to mannitol stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannitol stimulus. GO:0034500 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0034500 CHEBI:62759 beta-curcumene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62759 GO:0034501 protein localization to kinetochore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034501 protein localisation to kinetochore|condensin localization to kinetochore Any process in which a protein is transported to, or maintained at, the kinetochore. GO:0010552 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010552 GO:0009567 double fertilization forming a zygote and endosperm biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009567 double fertilization Fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the two polar nuclei to form the 3n primary endosperm nucleus and then develops into the endosperm. The ploidy level of the 2n zygote and 3n primary endosperm nucleus is determined by the ploidy level of the parents involved. An example of this component is found in Arabidopsis thaliana. CHEBI:62756 (-)-exo-alpha-bergamotene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_62756 GO:0009568 amyloplast starch grain biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009568 amyloplast starch granule Plant storage body for amylose and amylopectin, 1-100um in diameter, and located in amyloplasts. Also contains small amounts of enzymes, amino acids, lipids and nucleic acids. The shape of the grain varies widely amongst species, but is often spherical or disk-shaped. GO:0010553 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010553 GO:0034502 protein localization to chromosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034502 protein localisation to chromosome|condensin localization to chromosome Any process in which a protein is transported to, or maintained at, a specific location on a chromosome. GO:0009569 chloroplast starch grain biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009569 chloroplast starch granule Plant storage body for amylose and amylopectin, 1-100um in diameter, and located in chloroplasts. Also contains small amounts of enzymes, amino acids, lipids and nucleic acids. The shape of the grain varies widely amongst species, but is often spherical or disk-shaped. CHEBI:1506 3-fumarylpyruvic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_1506 GO:0034495 protein storage vacuole lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034495 The volume enclosed by the protein storage vacuole membrane. GO:0034496 multivesicular body membrane disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034496 MVB membrane disassembly The controlled breakdown of the membranes of multivesicular bodies. GO:0034497 protein localization to phagophore assembly site biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034497 protein localization to pre-autophagosomal structure|protein localization to PAS|protein localisation to phagophore assembly site Any process in which a protein is transported to, or maintained at, the phagophore assembly site (PAS). GO:0034498 early endosome to Golgi transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034498 PGE to Golgi transport|post-Golgi endosome to Golgi transport The directed movement of substances from early endosomes to the Golgi. GO:0034499 late endosome to Golgi transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034499 prevacuolar endosome to Golgi transport|PVE to Golgi transport The directed movement of substances from late endosomes to the Golgi. GO:0034490 basic amino acid transmembrane import into vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034490 The directed movement of basic amino acids into the vacuole across the vacuolar membrane. GO:0034491 neutral amino acid transmembrane import into vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034491 The directed movement of neutral amino acids into the vacuole across the vacuolar membrane. GO:0034492 hydrogenosome lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034492 The volume enclosed by the hydrogenosome membrane. GO:0034493 melanosome lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034493 The volume enclosed by the melanosome membrane. GO:0034494 microneme lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034494 The volume enclosed by the microneme membrane. GO:0034484 raffinose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034484 raffinose catabolism|raffinose degradation|raffinose breakdown The chemical reactions and pathways resulting in the breakdown of raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside. GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034485 MetaCyc:RXN-10036|Reactome:R-HSA-1675949|RHEA:25528 Catalysis of the reaction: phosphatidylinositol-3,4,5-trisphosphate + H2O = phosphatidylinositol-3,4-bisphosphate + phosphate. GO:0034486 vacuolar transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034486 vacuolar membrane transport The process in which a solute is transported from one side of the vacuolar membrane to the other. GO:0034487 vacuolar amino acid transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034487 vacuolar amino acid membrane transport The process in which an amino acid is transported from one side of the vacuolar membrane to the other. GO:0034488 basic amino acid transmembrane export from vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034488 The directed movement of basic amino acids out of the vacuole, across the vacuolar membrane. GO:0034489 neutral amino acid transmembrane export from vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034489 The directed movement of neutral amino acids out of the vacuole, across the vacuolar membrane. GO:0034480 phosphatidylcholine phospholipase C activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034480 EC:3.1.4.3|MetaCyc:PHOSPHOLIPASE-C-RXN|RHEA:10604 phospholipase C, acting on phosphatidylcholine|alpha-toxin|Clostridium oedematiens beta- and gamma-toxins activity|phosphatidylcholine cholinephosphohydrolase activity|Clostridium welchii alpha-toxin activity|heat-labile hemolysin|lipophosphodiesterase I activity Catalysis of the reaction: phosphatidylcholine + H2O = 1,2-diacylglycerol + a choline phosphate. GO:0034481 chondroitin sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034481 Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin sulfate. GO:0034482 chondroitin 2-O-sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034482 chondroitin 2-O-sulphotransferase activity|chondroitin 2-sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 2'-O-sulfate. Results in sulfation of glucuronic acid and iduronic acid residues. GO:0034483 heparan sulfate sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034483 Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + sulfated heparan sulfate. CHEBI:1549 3-hydroxymonocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_1549 GO:0034473 U1 snRNA 3'-end processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034473 U1 snRNA 3' end processing Any process involved in forming the mature 3' end of a U1 snRNA molecule. GO:0034474 U2 snRNA 3'-end processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034474 U2 snRNA 3' end processing Any process involved in forming the mature 3' end of a U2 snRNA molecule. GO:0034475 U4 snRNA 3'-end processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034475 U4 snRNA 3' end processing Any process involved in forming the mature 3' end of a U4 snRNA molecule. GO:0034476 U5 snRNA 3'-end processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034476 U5 snRNA 3' end processing Any process involved in forming the mature 3' end of a U5 snRNA molecule. GO:0034477 U6 snRNA 3'-end processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034477 U6 snRNA 3' end processing Any process involved in forming the mature 3' end of a U6 snRNA molecule. GO:0034478 phosphatidylglycerol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034478 phosphatidylglycerol degradation|phosphatidylglycerol breakdown|phosphatidylglycerol catabolism The chemical reactions and pathways resulting in the breakdown of phosphatidylglycerols, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol. GO:0034479 phosphatidylglycerol phospholipase C activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034479 Catalysis of the reaction: a phosphatidylglycerol + H2O = 1,2-diacylglycerol + glycerol 3-phosphate. CHEBI:1547 3-hydroxykynurenine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_1547 GO:0034470 ncRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034470 Any process that results in the conversion of one or more primary non-coding RNA (ncRNA) transcripts into one or more mature ncRNA molecules. GO:0034471 ncRNA 5'-end processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034471 ncRNA 5' end processing Any process involved in forming the mature 5' end of a non-coding RNA molecule. GO:0034472 snRNA 3'-end processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034472 snRNA 3' end processing Any process involved in forming the mature 3' end of an snRNA molecule. GO:0034462 small-subunit processome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034462 SSU processome assembly|small subunit processome assembly The aggregation, arrangement and bonding together of proteins and RNA molecules to form a small-subunit processome. GO:0034463 90S preribosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034463 The aggregation, arrangement and bonding together of proteins and RNA molecules to form a 90S preribosome. The 90S preribosome represents the complex that forms on the primary rRNA transcript before it splits into the small subunit and large subunit portions. GO:0034464 BBSome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034464 Bardet-Biedl syndrome complex A ciliary protein complex involved in cilium biogenesis. It consists of at least seven Bardet-Biedl syndrome (BBS) proteins and BBIP10. It moves in association with IFT trains through cilia (likely as an IFT-A/B adaptor or cargo), and is required for the integrity of IFT-A and IFT-B. GO:0034465 response to carbon monoxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034465 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon monoxide (CO) stimulus. GO:0034466 chromaffin granule lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034466 The volume enclosed by the membrane of a chromaffin granule. GO:0034467 esterosome lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034467 The volume enclosed by the membrane of an esterosome. GO:0034468 glycosome lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034468 The volume enclosed by the membrane of a glycosome. GO:0034469 Golgi stack lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034469 The volume enclosed by any of the membranes of the thin, flattened cisternae that form the central portion of the Golgi complex. GO:0034460 uropod assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034460 uropod formation The assembly of a uropod by rearrangement of the cytoskeleton and overlying membrane. GO:0034461 uropod retraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034461 The process in which a uropod detaches from the cell substrate and retracts the rear of a migrating cell. GO:1902939 negative regulation of intracellular calcium activated chloride channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902939 downregulation of intracellular calcium activated chloride channel activity|down-regulation of intracellular calcium activated chloride channel activity|inhibition of intracellular calcium activated chloride channel activity|down regulation of intracellular calcium activated chloride channel activity Any process that stops, prevents or reduces the frequency, rate or extent of intracellular calcium activated chloride channel activity. GO:1902937 inward rectifier potassium channel complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1902937 A protein complex which is capable of inward rectifier potassium channel activity. GO:1902938 regulation of intracellular calcium activated chloride channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902938 Any process that modulates the frequency, rate or extent of intracellular calcium activated chloride channel activity. GO:1902935 protein localization to septin ring biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902935 protein localisation to septin ring|protein localization in septin ring|protein localisation in septin ring A process in which a protein is transported to, or maintained in, a location within a septin ring. GO:1902936 phosphatidylinositol bisphosphate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1902936 Interacting selectively and non-covalently with phosphatidylinositol bisphosphate. GO:1902933 isopentenol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902933 isopentenol metabolism The chemical reactions and pathways involving isopentenol. GO:1902934 isopentenol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902934 isopentenol synthesis|isopentenol formation|isopentenol biosynthesis|isopentenol anabolism The chemical reactions and pathways resulting in the formation of isopentenol. GO:1902931 negative regulation of alcohol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902931 down regulation of alcohol anabolism|downregulation of alcohol biosynthesis|downregulation of alcohol biosynthetic process|down regulation of alcohol synthesis|downregulation of alcohol anabolism|down regulation of alcohol biosynthesis|down regulation of alcohol biosynthetic process|down regulation of alcohol formation|inhibition of alcohol biosynthesis|inhibition of alcohol biosynthetic process|downregulation of alcohol synthesis|downregulation of alcohol formation|down-regulation of alcohol anabolism|negative regulation of alcohol anabolism|negative regulation of solventogenesis|down-regulation of alcohol synthesis|negative regulation of alcohol synthesis|down-regulation of alcohol formation|negative regulation of alcohol formation|inhibition of alcohol anabolism|inhibition of alcohol synthesis|down-regulation of alcohol biosynthesis|down-regulation of alcohol biosynthetic process|negative regulation of alcohol biosynthesis|inhibition of alcohol formation Any process that stops, prevents or reduces the frequency, rate or extent of alcohol biosynthetic process. GO:1902932 positive regulation of alcohol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902932 positive regulation of alcohol biosynthesis|upregulation of alcohol anabolism|up regulation of alcohol biosynthesis|up regulation of alcohol biosynthetic process|upregulation of alcohol synthesis|upregulation of alcohol formation|up regulation of alcohol anabolism|upregulation of alcohol biosynthesis|upregulation of alcohol biosynthetic process|activation of alcohol anabolism|positive regulation of alcohol anabolism|up regulation of alcohol synthesis|activation of alcohol synthesis|positive regulation of solventogenesis|positive regulation of alcohol synthesis|up regulation of alcohol formation|activation of alcohol formation|positive regulation of alcohol formation|up-regulation of alcohol biosynthesis|up-regulation of alcohol biosynthetic process|activation of alcohol biosynthesis|activation of alcohol biosynthetic process|up-regulation of alcohol anabolism|up-regulation of alcohol synthesis|up-regulation of alcohol formation Any process that activates or increases the frequency, rate or extent of alcohol biosynthetic process. GO:1902930 regulation of alcohol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902930 regulation of alcohol anabolism|regulation of alcohol biosynthesis|regulation of solventogenesis|regulation of alcohol synthesis|regulation of alcohol formation Any process that modulates the frequency, rate or extent of alcohol biosynthetic process. CHEBI:37712 O-phosphoserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37712 CHEBI:37713 O-phospho-D-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37713 CHEBI:72058 phosphatidylserine 34:1(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72058 CHEBI:72059 phosphatidylserine 34:2(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72059 GO:1902948 negative regulation of tau-protein kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902948 negative regulation of TPK II|down-regulation of TPK II|down regulation of tau-protein kinase II activity|down regulation of GSK|inhibition of TPK I|down regulation of [Tau protein] kinase activity|down-regulation of tau-protein kinase I activity|negative regulation of tau-protein kinase I activity|down-regulation of TTK|downregulation of glycogen synthase kinase-3beta activity|negative regulation of TTK|down regulation of tau protein kinase activity|down-regulation of CDK5/p23|negative regulation of CDK5/p23|down regulation of protein tau kinase activity|negative regulation of STK31|down-regulation of STK31|inhibition of tau-protein kinase activity|negative regulation of brain protein kinase PK40erk activity|down-regulation of brain protein kinase PK40erk activity|downregulation of GSK|downregulation of [Tau protein] kinase activity|inhibition of tau-protein kinase II activity|down regulation of tau kinase activity|down-regulation of cdk5/p20|negative regulation of cdk5/p20|downregulation of protein tau kinase activity|down regulation of TPK I|downregulation of tau protein kinase activity|downregulation of TPK II|inhibition of TPK|downregulation of tau kinase activity|down-regulation of glycogen synthase kinase-3beta activity|negative regulation of glycogen synthase kinase-3beta activity|inhibition of tau-tubulin kinase activity|downregulation of TPK I|down regulation of TPK II|downregulation of CDK5/p23|inhibition of tau-protein kinase I activity|down-regulation of GSK|negative regulation of GSK|inhibition of TTK|negative regulation of [Tau protein] kinase activity|down-regulation of [Tau protein] kinase activity|downregulation of cdk5/p20|down regulation of tau-protein kinase activity|inhibition of STK31|down-regulation of protein tau kinase activity|inhibition of brain protein kinase PK40erk activity|negative regulation of protein tau kinase activity|down-regulation of tau protein kinase activity|negative regulation of tau protein kinase activity|down regulation of TPK|down regulation of CDK5/p23|inhibition of glycogen synthase kinase-3beta activity|down regulation of tau-tubulin kinase activity|negative regulation of tau-protein kinase II activity|down-regulation of tau-protein kinase II activity|inhibition of TPK II|down regulation of cdk5/p20|negative regulation of tau kinase activity|down-regulation of tau kinase activity|down-regulation of TPK I|down regulation of TTK|negative regulation of TPK I|down regulation of tau-protein kinase I activity|downregulation of TPK|downregulation of tau-protein kinase activity|downregulation of tau-tubulin kinase activity|inhibition of [Tau protein] kinase activity|inhibition of tau protein kinase activity|inhibition of CDK5/p23|down regulation of STK31|down regulation of brain protein kinase PK40erk activity|inhibition of protein tau kinase activity|downregulation of tau-protein kinase I activity|downregulation of TTK|inhibition of GSK|inhibition of tau kinase activity|inhibition of cdk5/p20|downregulation of tau-protein kinase II activity|downregulation of brain protein kinase PK40erk activity|downregulation of STK31|down regulation of glycogen synthase kinase-3beta activity|down-regulation of tau-protein kinase activity|down-regulation of TPK|negative regulation of TPK|negative regulation of tau-tubulin kinase activity|down-regulation of tau-tubulin kinase activity Any process that stops, prevents or reduces the frequency, rate or extent of tau-protein kinase activity. GO:1902949 positive regulation of tau-protein kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902949 upregulation of [Tau protein] kinase activity|up regulation of STK31|activation of TPK|activation of TPK II|activation of tau-tubulin kinase activity|up-regulation of cdk5/p20|positive regulation of brain protein kinase PK40erk activity|positive regulation of STK31|upregulation of protein tau kinase activity|upregulation of tau protein kinase activity|upregulation of tau-protein kinase II activity|activation of tau-protein kinase I activity|activation of CDK5/p23|activation of TTK|upregulation of tau kinase activity|positive regulation of TPK II|up-regulation of tau-protein kinase activity|up-regulation of tau-tubulin kinase activity|up regulation of glycogen synthase kinase-3beta activity|up-regulation of TPK|upregulation of TPK I|activation of brain protein kinase PK40erk activity|activation of cdk5/p20|up regulation of TPK II|activation of glycogen synthase kinase-3beta activity|activation of STK31|positive regulation of glycogen synthase kinase-3beta activity|up regulation of GSK|up-regulation of tau-protein kinase I activity|positive regulation of CDK5/p23|up regulation of [Tau protein] kinase activity|up-regulation of TTK|up regulation of CDK5/p23|activation of [Tau protein] kinase activity|positive regulation of GSK|up-regulation of brain protein kinase PK40erk activity|up regulation of tau protein kinase activity|up regulation of protein tau kinase activity|positive regulation of cdk5/p20|positive regulation of [Tau protein] kinase activity|up-regulation of tau-protein kinase II activity|activation of tau protein kinase activity|up-regulation of STK31|activation of protein tau kinase activity|positive regulation of protein tau kinase activity|positive regulation of tau protein kinase activity|up regulation of cdk5/p20|upregulation of tau-tubulin kinase activity|upregulation of tau-protein kinase activity|up regulation of tau kinase activity|upregulation of TPK|up regulation of TPK I|activation of tau kinase activity|activation of GSK|upregulation of TPK II|positive regulation of tau kinase activity|positive regulation of TPK I|upregulation of tau-protein kinase I activity|activation of tau-protein kinase II activity|upregulation of TTK|up-regulation of glycogen synthase kinase-3beta activity|upregulation of CDK5/p23|upregulation of brain protein kinase PK40erk activity|upregulation of STK31|up-regulation of GSK|up-regulation of [Tau protein] kinase activity|positive regulation of tau-protein kinase II activity|activation of TPK I|upregulation of cdk5/p20|up regulation of tau-protein kinase II activity|up-regulation of tau protein kinase activity|up regulation of TPK|up-regulation of protein tau kinase activity|up regulation of tau-tubulin kinase activity|up regulation of tau-protein kinase activity|activation of tau-protein kinase activity|up-regulation of TPK II|positive regulation of TPK|positive regulation of tau-tubulin kinase activity|upregulation of glycogen synthase kinase-3beta activity|up-regulation of tau kinase activity|up regulation of tau-protein kinase I activity|up regulation of TTK|up-regulation of TPK I|positive regulation of tau-protein kinase I activity|up-regulation of CDK5/p23|upregulation of GSK|up regulation of brain protein kinase PK40erk activity|positive regulation of TTK Any process that activates or increases the frequency, rate or extent of tau-protein kinase activity. GO:1902946 protein localization to early endosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902946 protein localisation to early endosome|protein localisation in early endosome|protein localization in early endosome A process in which a protein is transported to, or maintained in, a location within an early endosome. GO:1902947 regulation of tau-protein kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902947 regulation of glycogen synthase kinase-3beta activity|regulation of GSK|regulation of ATP:tau-protein O-phosphotransferase activity|regulation of [Tau protein] kinase activity|regulation of protein tau kinase activity|regulation of tau protein kinase activity|regulation of tau kinase activity|regulation of TPK I|regulation of TPK II|regulation of CDK5/p23|regulation of cdk5/p20|regulation of TPK|regulation of tau-tubulin kinase activity|regulation of tau-protein kinase I activity|regulation of TTK|regulation of brain protein kinase PK40erk activity|regulation of STK31|regulation of tau-protein kinase II activity Any process that modulates the frequency, rate or extent of tau-protein kinase activity. GO:1902944 aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1902944 aspartate protease activity involved in APP catabolic process|aspartate protease activity involved in amyloid precursor protein catabolism|aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|carboxyl protease activity involved in APP catabolic process|aspartic endopeptidase activity involved in amyloid precursor protein catabolism|aspartic protease activity involved in amyloid precursor protein breakdown|aspartyl protease activity involved in APP catabolism|aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|aspartyl protease activity involved in amyloid precursor protein degradation|aspartic endopeptidase activity involved in APP catabolic process|aspartic protease activity involved in amyloid precursor protein catabolic process|aspartyl protease activity involved in amyloid precursor protein breakdown|aspartyl protease activity involved in amyloid precursor protein catabolism|aspartic protease activity involved in APP catabolism|aspartic protease activity involved in APP catabolic process|aspartyl protease activity involved in amyloid precursor protein catabolic process|aspartic-type endopeptidase activity involved in APP catabolic process|aspartate protease activity involved in amyloid precursor protein degradation|aspartic protease activity involved in amyloid precursor protein catabolism|aspartic-type endopeptidase activity involved in APP catabolism|carboxyl protease activity involved in amyloid precursor protein degradation|aspartyl protease activity involved in APP catabolic process|aspartate protease activity involved in amyloid precursor protein breakdown|carboxyl protease activity involved in APP catabolism|aspartic endopeptidase activity involved in amyloid precursor protein degradation|carboxyl protease activity involved in amyloid precursor protein breakdown|aspartate protease activity involved in amyloid precursor protein catabolic process|aspartate protease activity involved in APP catabolism|aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|carboxyl protease activity involved in amyloid precursor protein catabolism|aspartic endopeptidase activity involved in APP catabolism|carboxyl protease activity involved in amyloid precursor protein catabolic process|aspartic endopeptidase activity involved in amyloid precursor protein breakdown|aspartic protease activity involved in amyloid precursor protein degradation Any aspartic-type endopeptidase activity that is involved in amyloid precursor protein catabolic process. GO:1902945 metalloendopeptidase activity involved in amyloid precursor protein catabolic process biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1902945 Reactome:R-HSA-9010034 metalloendoproteinase activity involved in amyloid precursor protein catabolic process|metalloendoprotease activity involved in amyloid precursor protein breakdown|metalloendoprotease activity involved in amyloid precursor protein catabolic process|metalloendoproteinase activity involved in APP catabolic process|metalloendopeptidase activity involved in APP catabolism|metalloendoprotease activity involved in APP catabolic process|metalloendopeptidase activity involved in amyloid precursor protein catabolism|metalloendoprotease activity involved in APP catabolism|metalloendopeptidase activity involved in amyloid precursor protein degradation|metalloendoproteinase activity involved in APP catabolism|metalloendopeptidase activity involved in amyloid precursor protein breakdown|metalloendoprotease activity involved in amyloid precursor protein catabolism|metalloendoproteinase activity involved in amyloid precursor protein degradation|metalloendoproteinase activity involved in amyloid precursor protein catabolism|metalloendoproteinase activity involved in amyloid precursor protein breakdown|metalloendoprotease activity involved in amyloid precursor protein degradation|metalloendopeptidase activity involved in APP catabolic process Any metalloendopeptidase activity that is involved in amyloid precursor protein catabolic process. GO:1902942 negative regulation of voltage-gated chloride channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902942 downregulation of voltage-dependent chloride channel activity|down-regulation of voltage gated chloride channel activity|down regulation of voltage-gated chloride channel activity|negative regulation of voltage gated chloride channel activity|downregulation of voltage-gated chloride channel activity|inhibition of voltage gated chloride channel activity|negative regulation of voltage-dependent chloride channel activity|down-regulation of voltage-dependent chloride channel activity|inhibition of voltage-dependent chloride channel activity|down-regulation of voltage-gated chloride channel activity|down regulation of voltage gated chloride channel activity|inhibition of voltage-gated chloride channel activity|downregulation of voltage gated chloride channel activity|down regulation of voltage-dependent chloride channel activity Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated chloride channel activity. GO:1902943 positive regulation of voltage-gated chloride channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902943 upregulation of voltage-gated chloride channel activity|up regulation of voltage-dependent chloride channel activity|activation of voltage-dependent chloride channel activity|positive regulation of voltage-dependent chloride channel activity|up-regulation of voltage gated chloride channel activity|up regulation of voltage-gated chloride channel activity|activation of voltage-gated chloride channel activity|up-regulation of voltage-dependent chloride channel activity|upregulation of voltage gated chloride channel activity|up-regulation of voltage-gated chloride channel activity|upregulation of voltage-dependent chloride channel activity|up regulation of voltage gated chloride channel activity|activation of voltage gated chloride channel activity|positive regulation of voltage gated chloride channel activity Any process that activates or increases the frequency, rate or extent of voltage-gated chloride channel activity. GO:1902940 positive regulation of intracellular calcium activated chloride channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902940 upregulation of intracellular calcium activated chloride channel activity|up regulation of intracellular calcium activated chloride channel activity|activation of intracellular calcium activated chloride channel activity|up-regulation of intracellular calcium activated chloride channel activity Any process that activates or increases the frequency, rate or extent of intracellular calcium activated chloride channel activity. GO:1902941 regulation of voltage-gated chloride channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902941 regulation of voltage gated chloride channel activity|regulation of voltage-dependent chloride channel activity Any process that modulates the frequency, rate or extent of voltage-gated chloride channel activity. CHEBI:37721 D-fructofuranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37721 CHEBI:37722 fructofuranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37722 CHEBI:37725 L-fructofuranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37725 CHEBI:37723 keto-fructose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37723 CHEBI:37724 keto-L-fructose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_37724 GO:1902959 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902959 regulation of carboxyl protease activity involved in APP catabolism|regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process|regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|regulation of aspartic protease activity involved in amyloid precursor protein degradation|regulation of aspartate protease activity involved in amyloid precursor protein catabolic process|regulation of aspartate protease activity involved in amyloid precursor protein catabolism|regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|regulation of carboxyl protease activity involved in amyloid precursor protein catabolism|regulation of carboxyl protease activity involved in APP catabolic process|regulation of aspartic protease activity involved in amyloid precursor protein breakdown|regulation of aspartyl protease activity involved in amyloid precursor protein degradation|regulation of aspartate protease activity involved in APP catabolic process|regulation of aspartic endopeptidase activity involved in APP catabolic process|regulation of aspartic protease activity involved in amyloid precursor protein catabolic process|regulation of aspartic-type endopeptidase activity involved in APP catabolic process|regulation of aspartyl protease activity involved in APP catabolism|regulation of aspartyl protease activity involved in amyloid precursor protein breakdown|regulation of aspartic protease activity involved in APP catabolic process|regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process|regulation of aspartyl protease activity involved in amyloid precursor protein catabolism|regulation of aspartic protease activity involved in APP catabolism|regulation of carboxyl protease activity involved in amyloid precursor protein degradation|regulation of aspartyl protease activity involved in APP catabolic process|regulation of aspartic-type endopeptidase activity involved in APP catabolism|regulation of aspartate protease activity involved in amyloid precursor protein degradation|regulation of aspartic protease activity involved in amyloid precursor protein catabolism|regulation of aspartic endopeptidase activity involved in APP catabolism|regulation of carboxyl protease activity involved in amyloid precursor protein breakdown|regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|regulation of aspartate protease activity involved in APP catabolism|regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|regulation of aspartate protease activity involved in amyloid precursor protein breakdown|regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation Any process that modulates the frequency, rate or extent of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process. GO:1902957 negative regulation of mitochondrial electron transport, NADH to ubiquinone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902957 inhibition of oxidative phosphorylation, NADH to ubiquinone|down regulation of complex I (NADH to ubiquinone)|inhibition of complex I (NADH to ubiquinone)|down-regulation of mitochondrial electron transport, NADH to ubiquinone|down regulation of oxidative phosphorylation, NADH to ubiquinone|downregulation of oxidative phosphorylation, NADH to ubiquinone|downregulation of mitochondrial electron transport, NADH to ubiquinone|negative regulation of complex I (NADH to ubiquinone)|down-regulation of complex I (NADH to ubiquinone)|down regulation of mitochondrial electron transport, NADH to ubiquinone|inhibition of mitochondrial electron transport, NADH to ubiquinone|down-regulation of oxidative phosphorylation, NADH to ubiquinone|negative regulation of oxidative phosphorylation, NADH to ubiquinone|downregulation of complex I (NADH to ubiquinone) Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone. GO:1902958 positive regulation of mitochondrial electron transport, NADH to ubiquinone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902958 up-regulation of oxidative phosphorylation, NADH to ubiquinone|up-regulation of mitochondrial electron transport, NADH to ubiquinone|activation of mitochondrial electron transport, NADH to ubiquinone|upregulation of complex I (NADH to ubiquinone)|upregulation of oxidative phosphorylation, NADH to ubiquinone|up-regulation of complex I (NADH to ubiquinone)|up regulation of mitochondrial electron transport, NADH to ubiquinone|activation of complex I (NADH to ubiquinone)|up regulation of oxidative phosphorylation, NADH to ubiquinone|positive regulation of oxidative phosphorylation, NADH to ubiquinone|activation of oxidative phosphorylation, NADH to ubiquinone|positive regulation of complex I (NADH to ubiquinone)|upregulation of mitochondrial electron transport, NADH to ubiquinone|up regulation of complex I (NADH to ubiquinone) Any process that activates or increases the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone. GO:1902955 positive regulation of early endosome to recycling endosome transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902955 up-regulation of early endosome to recycling endosome transport|activation of early endosome to recycling endosome transport|up regulation of early endosome to recycling endosome transport|upregulation of early endosome to recycling endosome transport Any process that activates or increases the frequency, rate or extent of early endosome to recycling endosome transport. GO:1902956 regulation of mitochondrial electron transport, NADH to ubiquinone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902956 regulation of oxidative phosphorylation, NADH to ubiquinone|regulation of complex I (NADH to ubiquinone) Any process that modulates the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone. GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902953 positive regulation of endoplasmic reticulum to Golgi transport|up regulation of endoplasmic reticulum to Golgi transport|up regulation of ER to Golgi vesicle-mediated transport|up-regulation of rough ER to cis-Golgi transport|up-regulation of rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport|upregulation of rough endoplasmic reticulum to cis-Golgi transport|upregulation of rough ER to cis-Golgi vesicle-mediated transport|upregulation of ER to Golgi transport|upregulation of endoplasmic reticulum to Golgi vesicle-mediated transport|upregulation of endoplasmic reticulum to Golgi transport|upregulation of ER to Golgi vesicle-mediated transport|upregulation of rough ER to cis-Golgi transport|upregulation of rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport|up-regulation of rough endoplasmic reticulum to cis-Golgi transport|activation of rough endoplasmic reticulum to cis-Golgi transport|up-regulation of rough ER to cis-Golgi vesicle-mediated transport|activation of rough ER to cis-Golgi vesicle-mediated transport|up regulation of ER to Golgi transport|up regulation of endoplasmic reticulum to Golgi vesicle-mediated transport|positive regulation of ER to Golgi transport|activation of ER to Golgi transport|positive regulation of endoplasmic reticulum to Golgi vesicle-mediated transport|activation of endoplasmic reticulum to Golgi vesicle-mediated transport|up-regulation of endoplasmic reticulum to Golgi transport|activation of endoplasmic reticulum to Golgi transport|up-regulation of ER to Golgi vesicle-mediated transport|activation of ER to Golgi vesicle-mediated transport|up regulation of rough ER to cis-Golgi transport|up regulation of rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport|positive regulation of rough ER to cis-Golgi transport|positive regulation of rough endoplasmic reticulum to cis-Golgi transport|activation of rough ER to cis-Golgi transport|activation of rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport|positive regulation of rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport|positive regulation of rough ER to cis-Golgi vesicle-mediated transport|up regulation of rough endoplasmic reticulum to cis-Golgi transport|up regulation of rough ER to cis-Golgi vesicle-mediated transport|up-regulation of ER to Golgi transport|up-regulation of endoplasmic reticulum to Golgi vesicle-mediated transport Any process that activates or increases the frequency, rate or extent of ER to Golgi vesicle-mediated transport. GO:1902954 regulation of early endosome to recycling endosome transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902954 Any process that modulates the frequency, rate or extent of early endosome to recycling endosome transport. GO:1902951 negative regulation of dendritic spine maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902951 inhibition of dendritic spine maintenance|down regulation of dendritic spine maintenance|downregulation of dendritic spine maintenance|down-regulation of dendritic spine maintenance Any process that stops, prevents or reduces the frequency, rate or extent of dendritic spine maintenance. GO:1902952 positive regulation of dendritic spine maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902952 up-regulation of dendritic spine maintenance|upregulation of dendritic spine maintenance|up regulation of dendritic spine maintenance|activation of dendritic spine maintenance Any process that activates or increases the frequency, rate or extent of dendritic spine maintenance. CHEBI:13769 aminohydroquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_13769 GO:1902950 regulation of dendritic spine maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902950 Any process that modulates the frequency, rate or extent of dendritic spine maintenance. CHEBI:72065 phosphatidylserine 36:1(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72065 CHEBI:72066 phosphatidylserine 36:2(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72066 CHEBI:72067 phosphatidylserine 36:3(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72067 CHEBI:72068 phosphatidylserine 36:4(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72068 GO:1902968 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1902968 GO:1902969 mitotic DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902969 DNA replication involved in S phase involved in mitotic cell cycle|mitotic cell cycle DNA replication|DNA replication during S phase involved in mitotic cell cycle|mitotic nuclear cell cycle DNA replication|nuclear cell cycle DNA replication involved in mitotic cell cycle|DNA replication involved in S-phase involved in mitotic cell cycle Any nuclear DNA replication that is involved in a mitotic cell cycle. GO:1902966 positive regulation of protein localization to early endosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902966 activation of protein localization to early endosome|up-regulation of protein localization to early endosome|upregulation of protein localization in early endosome|activation of protein localisation in early endosome|up-regulation of protein localisation in early endosome|positive regulation of protein localisation to early endosome|up regulation of protein localisation to early endosome|up-regulation of protein localization in early endosome|activation of protein localization in early endosome|up regulation of protein localization to early endosome|positive regulation of protein localisation in early endosome|upregulation of protein localisation to early endosome|up regulation of protein localisation in early endosome|positive regulation of protein localization in early endosome|upregulation of protein localization to early endosome|up regulation of protein localization in early endosome|up-regulation of protein localisation to early endosome|activation of protein localisation to early endosome|upregulation of protein localisation in early endosome Any process that activates or increases the frequency, rate or extent of protein localization to early endosome. GO:1902967 protein localization to mitotic spindle midzone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902967 protein localisation to mitotic spindle midzone|protein localization in mitotic spindle midzone|protein localisation in mitotic spindle midzone A process in which a protein is transported to, or maintained in, a location within a mitotic spindle midzone. GO:1902964 positive regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902964 up-regulation of metalloendopeptidase activity involved in APP catabolic process|up-regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|up regulation of metalloendoproteinase activity involved in amyloid precursor protein degradation|up-regulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|activation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|up-regulation of metalloendoproteinase activity involved in APP catabolic process|activation of metalloendoproteinase activity involved in APP catabolic process|upregulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process|positive regulation of metalloendoprotease activity involved in amyloid precursor protein degradation|positive regulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|up regulation of metalloendopeptidase activity involved in amyloid precursor protein degradation|up-regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|upregulation of metalloendoproteinase activity involved in APP catabolism|activation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|upregulation of metalloendoprotease activity involved in amyloid precursor protein catabolism|activation of metalloendopeptidase activity involved in amyloid precursor protein degradation|up regulation of metalloendoprotease activity involved in amyloid precursor protein degradation|up regulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|positive regulation of metalloendopeptidase activity involved in amyloid precursor protein degradation|up-regulation of metalloendoprotease activity involved in APP catabolic process|activation of metalloendoprotease activity involved in APP catabolic process|positive regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|up regulation of metalloendoprotease activity involved in APP catabolism|positive regulation of metalloendopeptidase activity involved in APP catabolism|upregulation of metalloendopeptidase activity involved in APP catabolic process|up regulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|positive regulation of metalloendoprotease activity involved in amyloid precursor protein breakdown|activation of metalloendoprotease activity involved in APP catabolism|upregulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|up regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|activation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|up regulation of metalloendopeptidase activity involved in APP catabolism|positive regulation of metalloendoprotease activity involved in APP catabolism|upregulation of metalloendoproteinase activity involved in amyloid precursor protein degradation|positive regulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|up regulation of metalloendoprotease activity involved in amyloid precursor protein breakdown|positive regulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|up regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process|up regulation of metalloendoproteinase activity involved in APP catabolism|positive regulation of metalloendoproteinase activity involved in APP catabolic process|activation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process|up regulation of metalloendoprotease activity involved in amyloid precursor protein catabolism|activation of metalloendoproteinase activity involved in APP catabolism|up regulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|positive regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|upregulation of metalloendoprotease activity involved in amyloid precursor protein degradation|upregulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|positive regulation of metalloendoproteinase activity involved in APP catabolism|activation of metalloendoprotease activity involved in amyloid precursor protein catabolism|up regulation of metalloendoproteinase activity involved in APP catabolic process|up-regulation of metalloendopeptidase activity involved in amyloid precursor protein degradation|positive regulation of metalloendoprotease activity involved in amyloid precursor protein catabolism|up regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|positive regulation of metalloendoprotease activity involved in APP catabolic process|up regulation of metalloendopeptidase activity involved in APP catabolic process|upregulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|up-regulation of metalloendoproteinase activity involved in amyloid precursor protein degradation|up regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|activation of metalloendopeptidase activity involved in APP catabolic process|activation of metalloendoproteinase activity involved in amyloid precursor protein degradation|upregulation of metalloendopeptidase activity involved in APP catabolism|positive regulation of metalloendopeptidase activity involved in APP catabolic process|up regulation of metalloendoprotease activity involved in APP catabolic process|activation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|upregulation of metalloendoprotease activity involved in amyloid precursor protein breakdown|up-regulation of metalloendoprotease activity involved in APP catabolism|up-regulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|positive regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|upregulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|activation of metalloendoprotease activity involved in amyloid precursor protein degradation|activation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|up-regulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|up-regulation of metalloendoprotease activity involved in amyloid precursor protein degradation|up-regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process|upregulation of metalloendopeptidase activity involved in amyloid precursor protein degradation|upregulation of metalloendoproteinase activity involved in APP catabolic process|up-regulation of metalloendoproteinase activity involved in APP catabolism|upregulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|up-regulation of metalloendoprotease activity involved in amyloid precursor protein catabolism|activation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|up-regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|up-regulation of metalloendopeptidase activity involved in APP catabolism|up-regulation of metalloendoprotease activity involved in amyloid precursor protein breakdown|activation of metalloendoprotease activity involved in amyloid precursor protein breakdown|activation of metalloendopeptidase activity involved in APP catabolism|upregulation of metalloendoprotease activity involved in APP catabolism|upregulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|upregulation of metalloendoprotease activity involved in APP catabolic process|positive regulation of metalloendoproteinase activity involved in amyloid precursor protein degradation Any process that activates or increases the frequency, rate or extent of metalloendopeptidase activity involved in amyloid precursor protein catabolic process. GO:1902965 regulation of protein localization to early endosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902965 regulation of protein localisation to early endosome|regulation of protein localisation in early endosome|regulation of protein localization in early endosome Any process that modulates the frequency, rate or extent of protein localization to early endosome. CHEBI:37708 altrose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37708 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902962 regulation of metalloendoprotease activity involved in APP catabolism|regulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|regulation of metalloendoproteinase activity involved in amyloid precursor protein degradation|regulation of metalloendoproteinase activity involved in APP catabolism|regulation of metalloendoprotease activity involved in amyloid precursor protein catabolism|regulation of metalloendoprotease activity involved in amyloid precursor protein degradation|regulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|regulation of metalloendopeptidase activity involved in APP catabolic process|regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|regulation of metalloendopeptidase activity involved in APP catabolism|regulation of metalloendoprotease activity involved in amyloid precursor protein breakdown|regulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|regulation of metalloendoproteinase activity involved in APP catabolic process|regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|regulation of metalloendoprotease activity involved in APP catabolic process|regulation of metalloendopeptidase activity involved in amyloid precursor protein degradation Any process that modulates the frequency, rate or extent of metalloendopeptidase activity involved in amyloid precursor protein catabolic process. GO:1902963 negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902963 downregulation of metalloendopeptidase activity involved in amyloid precursor protein degradation|inhibition of metalloendoproteinase activity involved in amyloid precursor protein catabolism|down regulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|down regulation of metalloendoprotease activity involved in APP catabolism|negative regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|down-regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|downregulation of metalloendoproteinase activity involved in amyloid precursor protein degradation|down-regulation of metalloendoprotease activity involved in amyloid precursor protein breakdown|down-regulation of metalloendopeptidase activity involved in APP catabolism|negative regulation of metalloendopeptidase activity involved in APP catabolism|negative regulation of metalloendoprotease activity involved in amyloid precursor protein breakdown|downregulation of metalloendoprotease activity involved in APP catabolism|downregulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|down regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process|down regulation of metalloendoproteinase activity involved in APP catabolism|down regulation of metalloendoprotease activity involved in amyloid precursor protein catabolism|down regulation of metalloendoproteinase activity involved in amyloid precursor protein degradation|negative regulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|down-regulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|downregulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|downregulation of metalloendoprotease activity involved in amyloid precursor protein degradation|negative regulation of metalloendoproteinase activity involved in APP catabolic process|inhibition of metalloendoproteinase activity involved in amyloid precursor protein degradation|downregulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process|negative regulation of metalloendopeptidase activity involved in amyloid precursor protein degradation|down-regulation of metalloendopeptidase activity involved in amyloid precursor protein degradation|down-regulation of metalloendoproteinase activity involved in APP catabolic process|down-regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|downregulation of metalloendoproteinase activity involved in APP catabolism|downregulation of metalloendoprotease activity involved in amyloid precursor protein catabolism|down regulation of metalloendopeptidase activity involved in APP catabolic process|downregulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|down regulation of metalloendoprotease activity involved in amyloid precursor protein degradation|down regulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|down regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|downregulation of metalloendoprotease activity involved in amyloid precursor protein breakdown|downregulation of metalloendopeptidase activity involved in APP catabolism|negative regulation of metalloendoprotease activity involved in APP catabolic process|inhibition of metalloendoprotease activity involved in amyloid precursor protein degradation|inhibition of metalloendoproteinase activity involved in amyloid precursor protein breakdown|negative regulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|down-regulation of metalloendoprotease activity involved in APP catabolic process|down-regulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|negative regulation of metalloendoprotease activity involved in APP catabolism|down-regulation of metalloendoprotease activity involved in APP catabolism|downregulation of metalloendopeptidase activity involved in APP catabolic process|inhibition of metalloendopeptidase activity involved in amyloid precursor protein degradation|downregulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|down regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|downregulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|down regulation of metalloendopeptidase activity involved in APP catabolism|down regulation of metalloendoprotease activity involved in amyloid precursor protein breakdown|inhibition of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|down-regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process|downregulation of metalloendoproteinase activity involved in APP catabolic process|down-regulation of metalloendoproteinase activity involved in APP catabolism|negative regulation of metalloendoproteinase activity involved in APP catabolism|inhibition of metalloendoprotease activity involved in amyloid precursor protein breakdown|downregulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|inhibition of metalloendopeptidase activity involved in APP catabolism|negative regulation of metalloendoprotease activity involved in amyloid precursor protein catabolism|down-regulation of metalloendoprotease activity involved in amyloid precursor protein catabolism|inhibition of metalloendoprotease activity involved in APP catabolism|inhibition of metalloendopeptidase activity involved in amyloid precursor protein breakdown|down regulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|down regulation of metalloendoproteinase activity involved in APP catabolic process|downregulation of metalloendoprotease activity involved in APP catabolic process|inhibition of metalloendoprotease activity involved in amyloid precursor protein catabolic process|down regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|inhibition of metalloendoproteinase activity involved in APP catabolic process|negative regulation of metalloendopeptidase activity involved in APP catabolic process|down-regulation of metalloendopeptidase activity involved in APP catabolic process|inhibition of metalloendopeptidase activity involved in amyloid precursor protein catabolic process|inhibition of metalloendopeptidase activity involved in amyloid precursor protein catabolism|negative regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|down-regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|down-regulation of metalloendoproteinase activity involved in amyloid precursor protein degradation|negative regulation of metalloendoproteinase activity involved in amyloid precursor protein degradation|inhibition of metalloendoproteinase activity involved in APP catabolism|down regulation of metalloendoprotease activity involved in APP catabolic process|inhibition of metalloendoprotease activity involved in amyloid precursor protein catabolism|down regulation of metalloendopeptidase activity involved in amyloid precursor protein degradation|inhibition of metalloendoprotease activity involved in APP catabolic process|inhibition of metalloendopeptidase activity involved in APP catabolic process|down-regulation of metalloendoprotease activity involved in amyloid precursor protein degradation|down-regulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|negative regulation of metalloendoprotease activity involved in amyloid precursor protein degradation|negative regulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown Any process that stops, prevents or reduces the frequency, rate or extent of metalloendopeptidase activity involved in amyloid precursor protein catabolic process. GO:1902960 negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902960 downregulation of aspartyl protease activity involved in APP catabolic process|down regulation of aspartic-type endopeptidase activity involved in APP catabolism|down-regulation of aspartic endopeptidase activity involved in APP catabolic process|negative regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|inhibition of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|downregulation of aspartyl protease activity involved in amyloid precursor protein catabolism|negative regulation of aspartic endopeptidase activity involved in APP catabolic process|down-regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|downregulation of aspartic protease activity involved in APP catabolism|inhibition of carboxyl protease activity involved in amyloid precursor protein catabolism|negative regulation of aspartic protease activity involved in amyloid precursor protein degradation|down-regulation of aspartic protease activity involved in amyloid precursor protein degradation|negative regulation of aspartate protease activity involved in amyloid precursor protein catabolism|down regulation of aspartate protease activity involved in amyloid precursor protein degradation|down-regulation of aspartate protease activity involved in amyloid precursor protein catabolism|down regulation of aspartic protease activity involved in amyloid precursor protein catabolism|negative regulation of aspartyl protease activity involved in APP catabolism|downregulation of aspartic endopeptidase activity involved in APP catabolism|down regulation of carboxyl protease activity involved in amyloid precursor protein degradation|down-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|down-regulation of aspartyl protease activity involved in APP catabolism|downregulation of aspartic-type endopeptidase activity involved in APP catabolism|downregulation of carboxyl protease activity involved in amyloid precursor protein breakdown|down regulation of aspartyl protease activity involved in APP catabolic process|inhibition of aspartate protease activity involved in APP catabolic process|inhibition of carboxyl protease activity involved in amyloid precursor protein degradation|down regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|downregulation of aspartate protease activity involved in APP catabolism|inhibition of aspartyl protease activity involved in APP catabolic process|down-regulation of carboxyl protease activity involved in APP catabolic process|negative regulation of carboxyl protease activity involved in APP catabolic process|down regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|inhibition of aspartic endopeptidase activity involved in APP catabolic process|down-regulation of aspartic protease activity involved in amyloid precursor protein breakdown|negative regulation of aspartic protease activity involved in amyloid precursor protein breakdown|downregulation of aspartate protease activity involved in amyloid precursor protein degradation|down regulation of aspartate protease activity involved in amyloid precursor protein breakdown|downregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|down regulation of aspartic endopeptidase activity involved in APP catabolism|down-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process|downregulation of aspartic protease activity involved in amyloid precursor protein catabolism|down-regulation of aspartyl protease activity involved in amyloid precursor protein degradation|inhibition of aspartic endopeptidase activity involved in APP catabolism|downregulation of carboxyl protease activity involved in amyloid precursor protein catabolic process|down regulation of carboxyl protease activity involved in APP catabolism|down regulation of carboxyl protease activity involved in amyloid precursor protein breakdown|negative regulation of aspartyl protease activity involved in amyloid precursor protein degradation|downregulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|inhibition of carboxyl protease activity involved in amyloid precursor protein breakdown|down-regulation of aspartyl protease activity involved in amyloid precursor protein catabolism|down regulation of aspartate protease activity involved in APP catabolism|negative regulation of aspartyl protease activity involved in amyloid precursor protein catabolism|down regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|downregulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|inhibition of aspartyl protease activity involved in APP catabolism|downregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|negative regulation of aspartic protease activity involved in amyloid precursor protein catabolic process|down-regulation of aspartic protease activity involved in APP catabolism|negative regulation of aspartic protease activity involved in APP catabolism|down-regulation of aspartic protease activity involved in amyloid precursor protein catabolic process|downregulation of aspartic protease activity involved in amyloid precursor protein degradation|inhibition of aspartate protease activity involved in APP catabolism|down regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|down regulation of aspartate protease activity involved in amyloid precursor protein catabolic process|downregulation of aspartate protease activity involved in amyloid precursor protein breakdown|downregulation of aspartate protease activity involved in amyloid precursor protein catabolism|downregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|inhibition of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|downregulation of carboxyl protease activity involved in APP catabolism|down regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process|down regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|downregulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|negative regulation of aspartyl protease activity involved in amyloid precursor protein breakdown|negative regulation of aspartic-type endopeptidase activity involved in APP catabolic process|inhibition of carboxyl protease activity involved in amyloid precursor protein catabolic process|negative regulation of aspartic-type endopeptidase activity involved in APP catabolism|down regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|down-regulation of aspartyl protease activity involved in amyloid precursor protein breakdown|down-regulation of aspartic-type endopeptidase activity involved in APP catabolic process|down-regulation of aspartic-type endopeptidase activity involved in APP catabolism|down regulation of carboxyl protease activity involved in amyloid precursor protein catabolism|down regulation of aspartic protease activity involved in amyloid precursor protein degradation|downregulation of carboxyl protease activity involved in APP catabolic process|inhibition of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|down regulation of aspartate protease activity involved in amyloid precursor protein catabolism|inhibition of aspartic protease activity involved in amyloid precursor protein degradation|down-regulation of aspartate protease activity involved in amyloid precursor protein degradation|inhibition of aspartyl protease activity involved in amyloid precursor protein catabolism|downregulation of aspartic protease activity involved in amyloid precursor protein breakdown|downregulation of aspartate protease activity involved in amyloid precursor protein catabolic process|negative regulation of aspartate protease activity involved in amyloid precursor protein degradation|negative regulation of aspartic protease activity involved in amyloid precursor protein catabolism|negative regulation of aspartic protease activity involved in APP catabolic process|inhibition of aspartate protease activity involved in amyloid precursor protein catabolism|inhibition of aspartic protease activity involved in APP catabolism|down-regulation of aspartic protease activity involved in amyloid precursor protein catabolism|down regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|down-regulation of aspartic protease activity involved in APP catabolic process|downregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process|negative regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|down-regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|inhibition of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|downregulation of aspartyl protease activity involved in amyloid precursor protein degradation|down-regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process|down regulation of aspartate protease activity involved in APP catabolic process|downregulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|negative regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process|downregulation of carboxyl protease activity involved in amyloid precursor protein catabolism|down regulation of carboxyl protease activity involved in APP catabolic process|inhibition of carboxyl protease activity involved in APP catabolic process|down-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|down regulation of aspartic protease activity involved in amyloid precursor protein breakdown|inhibition of aspartic-type endopeptidase activity involved in APP catabolism|down regulation of aspartic endopeptidase activity involved in APP catabolic process|downregulation of aspartic protease activity involved in amyloid precursor protein catabolic process|negative regulation of aspartate protease activity involved in amyloid precursor protein breakdown|down-regulation of aspartate protease activity involved in amyloid precursor protein breakdown|down regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process|inhibition of aspartic protease activity involved in amyloid precursor protein breakdown|inhibition of aspartate protease activity involved in amyloid precursor protein degradation|inhibition of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process|down regulation of aspartyl protease activity involved in amyloid precursor protein degradation|downregulation of aspartate protease activity involved in APP catabolic process|down-regulation of carboxyl protease activity involved in APP catabolism|negative regulation of carboxyl protease activity involved in APP catabolism|down regulation of aspartyl protease activity involved in APP catabolism|negative regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|inhibition of aspartic protease activity involved in amyloid precursor protein catabolism|inhibition of aspartyl protease activity involved in amyloid precursor protein degradation|down-regulation of carboxyl protease activity involved in amyloid precursor protein degradation|negative regulation of carboxyl protease activity involved in amyloid precursor protein degradation|downregulation of aspartyl protease activity involved in amyloid precursor protein breakdown|down-regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|downregulation of aspartic-type endopeptidase activity involved in APP catabolic process|down-regulation of aspartyl protease activity involved in APP catabolic process|negative regulation of aspartyl protease activity involved in APP catabolic process|down regulation of aspartic protease activity involved in amyloid precursor protein catabolic process|inhibition of aspartic endopeptidase activity involved in amyloid precursor protein degradation|downregulation of aspartic endopeptidase activity involved in APP catabolic process|negative regulation of aspartate protease activity involved in amyloid precursor protein catabolic process|down-regulation of aspartate protease activity involved in amyloid precursor protein catabolic process|inhibition of aspartic protease activity involved in amyloid precursor protein catabolic process|downregulation of aspartic protease activity involved in APP catabolic process|inhibition of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|down-regulation of aspartic endopeptidase activity involved in APP catabolism|downregulation of aspartyl protease activity involved in amyloid precursor protein catabolic process|negative regulation of aspartic endopeptidase activity involved in APP catabolism|down regulation of aspartyl protease activity involved in amyloid precursor protein breakdown|downregulation of aspartyl protease activity involved in APP catabolism|inhibition of aspartate protease activity involved in amyloid precursor protein breakdown|down-regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|negative regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|down regulation of aspartic-type endopeptidase activity involved in APP catabolic process|negative regulation of carboxyl protease activity involved in amyloid precursor protein catabolism|negative regulation of carboxyl protease activity involved in amyloid precursor protein breakdown|down-regulation of carboxyl protease activity involved in amyloid precursor protein catabolism|inhibition of carboxyl protease activity involved in APP catabolism|inhibition of aspartic-type endopeptidase activity involved in APP catabolic process|inhibition of aspartyl protease activity involved in amyloid precursor protein breakdown|down-regulation of carboxyl protease activity involved in amyloid precursor protein breakdown|down-regulation of aspartate protease activity involved in APP catabolism|down regulation of aspartyl protease activity involved in amyloid precursor protein catabolism|inhibition of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|negative regulation of aspartate protease activity involved in APP catabolism|down regulation of aspartic protease activity involved in APP catabolic process|down regulation of aspartic protease activity involved in APP catabolism|inhibition of aspartate protease activity involved in amyloid precursor protein catabolic process|down-regulation of aspartate protease activity involved in APP catabolic process|negative regulation of aspartate protease activity involved in APP catabolic process|down-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|down regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process|negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|inhibition of aspartic protease activity involved in APP catabolic process|down-regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process|inhibition of aspartyl protease activity involved in amyloid precursor protein catabolic process|downregulation of carboxyl protease activity involved in amyloid precursor protein degradation|negative regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process. GO:1902961 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902961 up regulation of aspartic endopeptidase activity involved in APP catabolism|up-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process|upregulation of aspartic protease activity involved in amyloid precursor protein catabolism|activation of aspartic protease activity involved in amyloid precursor protein breakdown|upregulation of aspartic protease activity involved in APP catabolic process|positive regulation of aspartate protease activity involved in APP catabolism|up-regulation of aspartyl protease activity involved in amyloid precursor protein degradation|upregulation of aspartyl protease activity involved in amyloid precursor protein catabolic process|upregulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|up-regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|activation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process|up regulation of carboxyl protease activity involved in amyloid precursor protein breakdown|up regulation of aspartate protease activity involved in APP catabolism|positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|activation of aspartyl protease activity involved in amyloid precursor protein degradation|up-regulation of carboxyl protease activity involved in amyloid precursor protein catabolism|up-regulation of aspartic protease activity involved in amyloid precursor protein catabolic process|positive regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process|up regulation of aspartyl protease activity involved in amyloid precursor protein catabolism|upregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|up regulation of aspartic protease activity involved in APP catabolism|positive regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|up regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|upregulation of aspartate protease activity involved in amyloid precursor protein breakdown|activation of aspartic protease activity involved in amyloid precursor protein catabolic process|positive regulation of aspartic protease activity involved in amyloid precursor protein degradation|positive regulation of aspartyl protease activity involved in amyloid precursor protein catabolism|activation of aspartyl protease activity involved in amyloid precursor protein catabolism|up-regulation of aspartate protease activity involved in APP catabolic process|up regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process|upregulation of carboxyl protease activity involved in APP catabolism|up regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|positive regulation of aspartate protease activity involved in amyloid precursor protein catabolism|up-regulation of aspartic-type endopeptidase activity involved in APP catabolic process|upregulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|up-regulation of aspartyl protease activity involved in amyloid precursor protein breakdown|upregulation of carboxyl protease activity involved in amyloid precursor protein degradation|activation of aspartic protease activity involved in APP catabolism|positive regulation of aspartic protease activity involved in APP catabolism|positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|up regulation of aspartic protease activity involved in amyloid precursor protein degradation|upregulation of aspartyl protease activity involved in APP catabolic process|activation of aspartyl protease activity involved in amyloid precursor protein breakdown|up-regulation of aspartic endopeptidase activity involved in APP catabolic process|up regulation of aspartic-type endopeptidase activity involved in APP catabolism|activation of aspartic-type endopeptidase activity involved in APP catabolic process|up regulation of aspartate protease activity involved in amyloid precursor protein catabolism|upregulation of aspartate protease activity involved in amyloid precursor protein catabolic process|positive regulation of carboxyl protease activity involved in APP catabolic process|positive regulation of aspartic-type endopeptidase activity involved in APP catabolism|up regulation of aspartate protease activity involved in amyloid precursor protein degradation|up-regulation of aspartic protease activity involved in APP catabolic process|up regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|activation of aspartic-type endopeptidase activity involved in APP catabolism|upregulation of aspartic endopeptidase activity involved in APP catabolism|positive regulation of aspartic protease activity involved in amyloid precursor protein breakdown|up-regulation of aspartyl protease activity involved in APP catabolism|activation of aspartic protease activity involved in APP catabolic process|up-regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process|upregulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|up regulation of aspartic protease activity involved in amyloid precursor protein catabolism|positive regulation of aspartate protease activity involved in amyloid precursor protein degradation|upregulation of carboxyl protease activity involved in amyloid precursor protein breakdown|up regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|activation of aspartate protease activity involved in amyloid precursor protein degradation|activation of aspartyl protease activity involved in amyloid precursor protein catabolic process|up regulation of carboxyl protease activity involved in APP catabolic process|upregulation of carboxyl protease activity involved in amyloid precursor protein catabolism|upregulation of aspartate protease activity involved in APP catabolism|up regulation of aspartic protease activity involved in amyloid precursor protein breakdown|activation of aspartic protease activity involved in amyloid precursor protein catabolism|positive regulation of aspartyl protease activity involved in amyloid precursor protein degradation|positive regulation of aspartic protease activity involved in amyloid precursor protein catabolism|positive regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|up regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|activation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|up regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process|upregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|upregulation of aspartate protease activity involved in APP catabolic process|up regulation of aspartyl protease activity involved in amyloid precursor protein degradation|positive regulation of aspartic protease activity involved in amyloid precursor protein catabolic process|up regulation of aspartate protease activity involved in amyloid precursor protein breakdown|activation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|up-regulation of carboxyl protease activity involved in amyloid precursor protein degradation|up regulation of carboxyl protease activity involved in APP catabolism|upregulation of carboxyl protease activity involved in amyloid precursor protein catabolic process|positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|activation of carboxyl protease activity involved in amyloid precursor protein degradation|up regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|up-regulation of aspartyl protease activity involved in APP catabolic process|up regulation of aspartic protease activity involved in amyloid precursor protein catabolic process|upregulation of aspartic endopeptidase activity involved in APP catabolic process|upregulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|activation of aspartate protease activity involved in amyloid precursor protein breakdown|positive regulation of aspartate protease activity involved in amyloid precursor protein breakdown|up-regulation of aspartyl protease activity involved in amyloid precursor protein catabolism|upregulation of aspartic protease activity involved in amyloid precursor protein degradation|up-regulation of aspartic protease activity involved in APP catabolism|activation of carboxyl protease activity involved in APP catabolism|positive regulation of aspartyl protease activity involved in amyloid precursor protein breakdown|activation of aspartyl protease activity involved in APP catabolic process|positive regulation of carboxyl protease activity involved in APP catabolism|positive regulation of aspartic-type endopeptidase activity involved in APP catabolic process|up regulation of aspartate protease activity involved in amyloid precursor protein catabolic process|upregulation of aspartate protease activity involved in amyloid precursor protein catabolism|activation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|positive regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|upregulation of aspartyl protease activity involved in APP catabolism|upregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|up-regulation of aspartic endopeptidase activity involved in APP catabolism|up regulation of aspartyl protease activity involved in amyloid precursor protein breakdown|up regulation of aspartic-type endopeptidase activity involved in APP catabolic process|positive regulation of aspartate protease activity involved in amyloid precursor protein catabolic process|up-regulation of aspartic-type endopeptidase activity involved in APP catabolism|up-regulation of carboxyl protease activity involved in amyloid precursor protein breakdown|up regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|activation of aspartate protease activity involved in amyloid precursor protein catabolic process|activation of aspartic endopeptidase activity involved in APP catabolism|positive regulation of aspartic protease activity involved in APP catabolic process|up-regulation of aspartate protease activity involved in APP catabolism|activation of carboxyl protease activity involved in amyloid precursor protein breakdown|positive regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process|upregulation of carboxyl protease activity involved in APP catabolic process|up regulation of carboxyl protease activity involved in amyloid precursor protein catabolism|activation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|positive regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|up regulation of aspartic protease activity involved in APP catabolic process|activation of aspartate protease activity involved in APP catabolism|up-regulation of aspartate protease activity involved in amyloid precursor protein degradation|upregulation of aspartic protease activity involved in amyloid precursor protein breakdown|upregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process|activation of carboxyl protease activity involved in amyloid precursor protein catabolism|up-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|positive regulation of carboxyl protease activity involved in amyloid precursor protein catabolism|up regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process|up-regulation of aspartic protease activity involved in amyloid precursor protein catabolism|up regulation of aspartate protease activity involved in APP catabolic process|up-regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|up-regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process|upregulation of aspartyl protease activity involved in amyloid precursor protein degradation|activation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|upregulation of aspartyl protease activity involved in amyloid precursor protein catabolism|activation of carboxyl protease activity involved in amyloid precursor protein catabolic process|up-regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|upregulation of aspartic protease activity involved in amyloid precursor protein catabolic process|up-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|positive regulation of carboxyl protease activity involved in amyloid precursor protein degradation|activation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|upregulation of aspartic protease activity involved in APP catabolism|up-regulation of aspartic protease activity involved in amyloid precursor protein degradation|activation of aspartate protease activity involved in APP catabolic process|up regulation of aspartic endopeptidase activity involved in APP catabolic process|positive regulation of aspartate protease activity involved in APP catabolic process|positive regulation of aspartyl protease activity involved in APP catabolic process|up-regulation of aspartate protease activity involved in amyloid precursor protein breakdown|up-regulation of aspartate protease activity involved in amyloid precursor protein catabolism|activation of aspartic protease activity involved in amyloid precursor protein degradation|up-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|positive regulation of aspartic endopeptidase activity involved in APP catabolic process|up regulation of carboxyl protease activity involved in amyloid precursor protein degradation|up-regulation of carboxyl protease activity involved in APP catabolism|activation of aspartic endopeptidase activity involved in APP catabolic process|activation of aspartate protease activity involved in amyloid precursor protein catabolism|up regulation of aspartyl protease activity involved in APP catabolism|up regulation of aspartyl protease activity involved in APP catabolic process|upregulation of aspartic-type endopeptidase activity involved in APP catabolism|activation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|up-regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|upregulation of aspartyl protease activity involved in amyloid precursor protein breakdown|upregulation of aspartic-type endopeptidase activity involved in APP catabolic process|up-regulation of carboxyl protease activity involved in APP catabolic process|positive regulation of aspartic endopeptidase activity involved in APP catabolism|positive regulation of aspartyl protease activity involved in APP catabolism|activation of carboxyl protease activity involved in APP catabolic process|up-regulation of aspartate protease activity involved in amyloid precursor protein catabolic process|up-regulation of aspartic protease activity involved in amyloid precursor protein breakdown|upregulation of aspartate protease activity involved in amyloid precursor protein degradation|positive regulation of carboxyl protease activity involved in amyloid precursor protein breakdown|activation of aspartyl protease activity involved in APP catabolism Any process that activates or increases the frequency, rate or extent of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process. CHEBI:13759 alkylamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_13759 CHEBI:37700 EC 2.7.11.13 (protein kinase C) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37700 CHEBI:13757 n-alk-2-enal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_13757 CHEBI:37702 aldonate ester phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_37702 CHEBI:72075 phosphatidylserine 38:4(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72075 CHEBI:72076 phosphatidylserine 38:5(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72076 CHEBI:72077 phosphatidylserine 38:6(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72077 CHEBI:589779 piperidinium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_589779 GO:1902979 mitotic DNA replication termination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902979 DNA replication termination involved in mitotic cell cycle DNA replication Any DNA replication termination involved in mitotic cell cycle DNA replication. GO:1902977 mitotic DNA replication preinitiation complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902977 DNA replication preinitiation complex formation involved in mitotic cell cycle|pre-IC complex assembly involved in mitotic cell cycle Any DNA replication preinitiation complex assembly that is involved in mitotic cell cycle. GO:1902978 premeiotic DNA replication termination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902978 DNA replication termination involved in meiotic DNA replication|DNA replication termination involved in meiotic cell cycle DNA replication Any DNA replication termination involved in meiotic cell cycle DNA replication. GO:1902975 mitotic DNA replication initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902975 DNA replication initiation involved in mitotic cell cycle DNA replication Any DNA replication initiation involved in mitotic cell cycle DNA replication. GO:1902976 premeiotic DNA replication preinitiation complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902976 pre-IC complex assembly involved in meiotic cell cycle|DNA replication preinitiation complex formation involved in meiotic cell cycle Any DNA replication preinitiation complex assembly that is involved in meiotic cell cycle. GO:1902973 mitotic DNA replication DNA ligation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902973 DNA ligation involved in mitotic cell cycle DNA replication|DNA ligation involved in mitotic DNA replication Any DNA ligation involved in mitotic cell cycle DNA replication. GO:1902974 meiotic DNA replication initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902974 premeiotic DNA replication initiation|DNA replication initiation involved in meiotic cell cycle DNA replication|meiotic DNA replication initiation|initiation of premeiotic DNA synthesis|initiation of premeiotic DNA replication|initiation of meiotic DNA synthesis|DNA replication initiation involved in meiotic DNA replication Any DNA replication initiation involved in meiotic cell cycle DNA replication. GO:1902971 mitotic DNA replication DNA duplex unwinding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902971 DNA duplex unwinding involved in mitotic DNA replication|DNA duplex unwinding involved in mitotic cell cycle DNA replication Any DNA duplex unwinding involved in mitotic cell cycle DNA replication. GO:1902972 premeiotic DNA replication DNA ligation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902972 DNA ligation involved in meiotic DNA replication|DNA ligation involved in meiotic cell cycle DNA replication Any DNA ligation involved in meiotic cell cycle DNA replication. CHEBI:13705 acetoacetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_13705 GO:1902970 premeiotic DNA replication DNA duplex unwinding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902970 DNA duplex unwinding involved in meiotic DNA replication|DNA duplex unwinding involved in meiotic cell cycle DNA replication Any DNA duplex unwinding involved in meiotic cell cycle DNA replication. CHEBI:72084 phosphatidylserine 40:6(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72084 GO:1902988 neurofibrillary tangle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902988 neurofibrillary tangle formation|star-shaped neurofibrillary tangle assembly|flame-shaped neurofibrillary tangle assembly|flame-shaped neurofibrillary tangle formation|star-shaped neurofibrillary tangle formation The aggregation, arrangement and bonding together of a set of components to form a neurofibrillary tangle. GO:1902989 meiotic telomere maintenance via semi-conservative replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902989 telomeric fork progression involved in meiotic cell cycle|equal telomere replication involved in meiotic cell cycle|telomeric replication fork progression involved in meiotic cell cycle Any telomere maintenance via semi-conservative replication that is involved in meiotic cell cycle. GO:1902986 regulation of lysine biosynthetic process via aminoadipic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902986 regulation of lysine biosynthesis, aminoadipic pathway|regulation of lysine biosynthetic process, aminoadipic pathway|regulation of lysine biosynthetic process, aminoadipic acid pathway|regulation of lysine biosynthesis, aminoadipic acid pathway|regulation of lysine formation via aminoadipic acid|regulation of lysine synthesis via aminoadipic acid|regulation of lysine anabolism via aminoadipic acid Any process that modulates the frequency, rate or extent of lysine biosynthetic process via aminoadipic acid. GO:1902987 negative regulation of lysine biosynthetic process via aminoadipic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902987 negative regulation of lysine synthesis via aminoadipic acid|down-regulation of lysine synthesis via aminoadipic acid|inhibition of lysine formation via aminoadipic acid|down-regulation of lysine anabolism via aminoadipic acid|negative regulation of lysine anabolism via aminoadipic acid|downregulation of lysine biosynthesis, aminoadipic pathway|downregulation of lysine biosynthetic process, aminoadipic pathway|down regulation of lysine biosynthesis, aminoadipic acid pathway|inhibition of lysine synthesis via aminoadipic acid|down regulation of lysine biosynthetic process, aminoadipic acid pathway|down-regulation of lysine biosynthetic process via aminoadipic acid|down regulation of lysine biosynthesis, aminoadipic pathway|down regulation of lysine biosynthetic process, aminoadipic pathway|inhibition of lysine anabolism via aminoadipic acid|downregulation of lysine biosynthetic process, aminoadipic acid pathway|downregulation of lysine biosynthesis, aminoadipic acid pathway|inhibition of lysine biosynthesis, aminoadipic pathway|inhibition of lysine biosynthetic process, aminoadipic pathway|down regulation of lysine formation via aminoadipic acid|downregulation of lysine biosynthetic process via aminoadipic acid|down regulation of lysine synthesis via aminoadipic acid|down-regulation of lysine biosynthesis, aminoadipic acid pathway|negative regulation of lysine biosynthetic process, aminoadipic acid pathway|downregulation of lysine formation via aminoadipic acid|down-regulation of lysine biosynthetic process, aminoadipic acid pathway|negative regulation of lysine biosynthesis, aminoadipic acid pathway|down regulation of lysine biosynthetic process via aminoadipic acid|downregulation of lysine synthesis via aminoadipic acid|down regulation of lysine anabolism via aminoadipic acid|inhibition of lysine biosynthetic process via aminoadipic acid|downregulation of lysine anabolism via aminoadipic acid|inhibition of lysine biosynthetic process, aminoadipic acid pathway|inhibition of lysine biosynthesis, aminoadipic acid pathway|negative regulation of lysine biosynthesis, aminoadipic pathway|negative regulation of lysine biosynthetic process, aminoadipic pathway|down-regulation of lysine biosynthetic process, aminoadipic pathway|down-regulation of lysine biosynthesis, aminoadipic pathway|negative regulation of lysine formation via aminoadipic acid|down-regulation of lysine formation via aminoadipic acid Any process that stops, prevents or reduces the frequency, rate or extent of lysine biosynthetic process via aminoadipic acid. GO:1902984 pre-replicative complex assembly involved in premeiotic DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902984 nuclear pre-replicative complex assembly involved in meiotic cell cycle|pre-replicative complex assembly involved in meiosis|pre-RC complex assembly involved in meiosis|pre-replicative complex assembly involved in meiotic cell cycle DNA replication|pre-replicative complex formation involved in meiosis Any pre-replicative complex assembly involved in meiotic cell cycle DNA replication. GO:1902985 mitotic pre-replicative complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902985 pre-replicative complex assembly involved in mitotic cell cycle DNA replication|nuclear pre-replicative complex assembly involved in mitotic cell cycle Any pre-replicative complex assembly involved in mitotic cell cycle DNA replication. GO:1902982 DNA strand elongation involved in premeiotic DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902982 DNA strand elongation involved in meiotic cell cycle DNA replication Any DNA strand elongation involved in meiotic cell cycle DNA replication. GO:1902983 DNA strand elongation involved in mitotic DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902983 DNA strand elongation involved in mitotic cell cycle DNA replication Any DNA strand elongation involved in mitotic cell cycle DNA replication. GO:1902980 synthesis of RNA primer involved in premeiotic DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902980 synthesis of RNA primer involved in meiotic cell cycle DNA replication Any synthesis of RNA primer involved in meiotic cell cycle DNA replication. GO:1902981 synthesis of RNA primer involved in mitotic DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902981 synthesis of RNA primer involved in mitotic cell cycle DNA replication Any synthesis of RNA primer involved in mitotic cell cycle DNA replication. GO:1902990 mitotic telomere maintenance via semi-conservative replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902990 telomeric replication fork progression involved in mitotic cell cycle|telomeric fork progression involved in mitotic cell cycle|equal telomere replication involved in mitotic cell cycle Any telomere maintenance via semi-conservative replication that is involved in mitotic cell cycle. GO:1902999 negative regulation of phospholipid efflux biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902999 down regulation of phospholipid export|downregulation of phospholipid export|down regulation of phospholipid efflux|negative regulation of phospholipid export|down-regulation of phospholipid export|downregulation of phospholipid efflux|inhibition of phospholipid export|down-regulation of phospholipid efflux|inhibition of phospholipid efflux Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid efflux. GO:1902997 negative regulation of neurofibrillary tangle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902997 inhibition of neurofibrillary tangle assembly|down-regulation of flame-shaped neurofibrillary tangle formation|negative regulation of flame-shaped neurofibrillary tangle formation|inhibition of star-shaped neurofibrillary tangle assembly|downregulation of flame-shaped neurofibrillary tangle assembly|negative regulation of star-shaped neurofibrillary tangle formation|down-regulation of star-shaped neurofibrillary tangle formation|down regulation of flame-shaped neurofibrillary tangle assembly|down regulation of star-shaped neurofibrillary tangle assembly|down regulation of neurofibrillary tangle assembly|downregulation of star-shaped neurofibrillary tangle assembly|down-regulation of neurofibrillary tangle formation|negative regulation of neurofibrillary tangle formation|inhibition of flame-shaped neurofibrillary tangle formation|inhibition of flame-shaped neurofibrillary tangle assembly|downregulation of neurofibrillary tangle assembly|downregulation of star-shaped neurofibrillary tangle formation|down regulation of star-shaped neurofibrillary tangle formation|down regulation of flame-shaped neurofibrillary tangle formation|down-regulation of star-shaped neurofibrillary tangle assembly|negative regulation of star-shaped neurofibrillary tangle assembly|downregulation of neurofibrillary tangle formation|down-regulation of neurofibrillary tangle assembly|downregulation of flame-shaped neurofibrillary tangle formation|inhibition of star-shaped neurofibrillary tangle formation|negative regulation of flame-shaped neurofibrillary tangle assembly|down regulation of neurofibrillary tangle formation|down-regulation of flame-shaped neurofibrillary tangle assembly|inhibition of neurofibrillary tangle formation Any process that stops, prevents or reduces the frequency, rate or extent of neurofibrillary tangle assembly. GO:1902998 positive regulation of neurofibrillary tangle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902998 positive regulation of flame-shaped neurofibrillary tangle assembly|upregulation of neurofibrillary tangle formation|up-regulation of star-shaped neurofibrillary tangle formation|up regulation of flame-shaped neurofibrillary tangle assembly|up-regulation of neurofibrillary tangle assembly|activation of flame-shaped neurofibrillary tangle formation|activation of star-shaped neurofibrillary tangle formation|upregulation of star-shaped neurofibrillary tangle assembly|activation of neurofibrillary tangle formation|up-regulation of neurofibrillary tangle formation|up-regulation of flame-shaped neurofibrillary tangle formation|upregulation of neurofibrillary tangle assembly|upregulation of flame-shaped neurofibrillary tangle assembly|positive regulation of star-shaped neurofibrillary tangle formation|up regulation of star-shaped neurofibrillary tangle formation|up regulation of star-shaped neurofibrillary tangle assembly|positive regulation of star-shaped neurofibrillary tangle assembly|upregulation of flame-shaped neurofibrillary tangle formation|positive regulation of neurofibrillary tangle formation|up regulation of neurofibrillary tangle assembly|up-regulation of flame-shaped neurofibrillary tangle assembly|up regulation of neurofibrillary tangle formation|activation of neurofibrillary tangle assembly|activation of star-shaped neurofibrillary tangle assembly|upregulation of star-shaped neurofibrillary tangle formation|activation of flame-shaped neurofibrillary tangle assembly|up regulation of flame-shaped neurofibrillary tangle formation|up-regulation of star-shaped neurofibrillary tangle assembly|positive regulation of flame-shaped neurofibrillary tangle formation Any process that activates or increases the frequency, rate or extent of neurofibrillary tangle assembly. GO:1902995 positive regulation of phospholipid efflux biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902995 upregulation of phospholipid efflux|up regulation of phospholipid export|activation of phospholipid export|positive regulation of phospholipid export|up regulation of phospholipid efflux|activation of phospholipid efflux|up-regulation of phospholipid export|upregulation of phospholipid export|up-regulation of phospholipid efflux Any process that activates or increases the frequency, rate or extent of phospholipid efflux. GO:1902996 regulation of neurofibrillary tangle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902996 regulation of flame-shaped neurofibrillary tangle assembly|regulation of star-shaped neurofibrillary tangle assembly|regulation of star-shaped neurofibrillary tangle formation|regulation of flame-shaped neurofibrillary tangle formation|regulation of neurofibrillary tangle formation Any process that modulates the frequency, rate or extent of neurofibrillary tangle assembly. GO:1902993 positive regulation of amyloid precursor protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902993 positive regulation of amyloid precursor protein breakdown|activation of amyloid precursor protein breakdown|up-regulation of amyloid precursor protein catabolism|up regulation of amyloid precursor protein catabolic process|activation of amyloid precursor protein catabolism|activation of amyloid precursor protein catabolic process|positive regulation of APP catabolism|up-regulation of amyloid precursor protein degradation|up regulation of APP catabolism|up regulation of APP catabolic process|positive regulation of APP catabolic process|activation of APP catabolic process|up-regulation of amyloid precursor protein breakdown|positive regulation of amyloid precursor protein catabolism|up regulation of amyloid precursor protein catabolism|up-regulation of amyloid precursor protein catabolic process|upregulation of amyloid precursor protein degradation|upregulation of APP catabolism|upregulation of amyloid precursor protein breakdown|up-regulation of APP catabolic process|upregulation of amyloid precursor protein catabolic process|upregulation of amyloid precursor protein catabolism|up regulation of amyloid precursor protein degradation|positive regulation of amyloid precursor protein degradation|up-regulation of APP catabolism|activation of amyloid precursor protein degradation|activation of APP catabolism|up regulation of amyloid precursor protein breakdown|upregulation of APP catabolic process Any process that activates or increases the frequency, rate or extent of amyloid precursor protein catabolic process. GO:1902994 regulation of phospholipid efflux biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902994 regulation of phospholipid export Any process that modulates the frequency, rate or extent of phospholipid efflux. GO:1902991 regulation of amyloid precursor protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902991 regulation of APP catabolic process|regulation of APP catabolism|regulation of amyloid precursor protein catabolism|regulation of amyloid precursor protein degradation|regulation of amyloid precursor protein breakdown Any process that modulates the frequency, rate or extent of amyloid precursor protein catabolic process. GO:1902992 negative regulation of amyloid precursor protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1902992 down regulation of APP catabolic process|negative regulation of APP catabolism|down-regulation of APP catabolism|down-regulation of amyloid precursor protein breakdown|negative regulation of amyloid precursor protein breakdown|downregulation of APP catabolic process|inhibition of amyloid precursor protein degradation|negative regulation of amyloid precursor protein catabolism|down-regulation of amyloid precursor protein catabolic process|down-regulation of amyloid precursor protein catabolism|downregulation of APP catabolism|inhibition of amyloid precursor protein breakdown|down-regulation of APP catabolic process|negative regulation of APP catabolic process|inhibition of amyloid precursor protein catabolic process|down regulation of APP catabolism|downregulation of amyloid precursor protein catabolism|inhibition of APP catabolism|down regulation of amyloid precursor protein degradation|inhibition of APP catabolic process|down regulation of amyloid precursor protein catabolism|downregulation of amyloid precursor protein degradation|inhibition of amyloid precursor protein catabolism|down regulation of amyloid precursor protein breakdown|down regulation of amyloid precursor protein catabolic process|downregulation of amyloid precursor protein breakdown|downregulation of amyloid precursor protein catabolic process|down-regulation of amyloid precursor protein degradation|negative regulation of amyloid precursor protein degradation Any process that stops, prevents or reduces the frequency, rate or extent of amyloid precursor protein catabolic process. OBO:GOCHE_26348 substance with prosthetic group role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_26348 CHEBI:13719 acetylsalicylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_13719 CHEBI:13714 1-O-acetylmaltose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_13714 CHEBI:13711 acetyl phosphate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_13711 UBERON:0004819 kidney epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004819 epithelium of kidney|kidney epithelial tissue|renal epithelium|epithelial tissue of kidney the cellular avascular layer of the kidney luminar surfaces UBERON:0004817 lacrimal gland epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004817 epithelial tissue of lacrimal gland|epithelium of lacrimal gland|lacrimal gland epithelial tissue An epithelium that is part of a lacrimal gland [Automatically generated definition]. UBERON:0004815 lower respiratory tract epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004815 epithelial tissue of lower respiratory tract|lower respiratory tract epithelial tissue|epithelium of lower respiratory tract An epithelium that is part of a lower respiratory tract [Automatically generated definition]. UBERON:0004816 larynx epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004816 laryngeal epithelium|epithelial tissue of larynx|epithelium of larynx|larynx epithelial tissue An epithelium that is part of a larynx [Automatically generated definition]. UBERON:0004813 seminiferous tubule epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004813 male germinal epithelium|seminiferous epithelium|epithelium of seminiferous tubule of testis|epithelial tissue of seminiferous tubule of testis|testis germinal epithelium|epithelium of seminiferous tubule|epithelial tissue of seminiferous tubule|wall of seminiferous tubule|germinal epithelium (male)|seminiferous tubule epithelial tissue the stratified epithelial lining of the seminiferous tubules, consisting of the developing spermatozoa and the supporting Sertoli cells, which are tall, columnar type cells that line the tubule UBERON:0004814 upper respiratory tract epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004814 upper respiratory tract epithelial tissue|epithelium of upper respiratory tract|epithelial tissue of upper respiratory tract An epithelium that is part of a upper respiratory tract [Automatically generated definition]. GO:0034613 cellular protein localization biolink:BiologicalProcess go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0034613 channel localizer activity|cellular protein localisation Any process in which a protein is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell. GO:0010646 regulation of cell communication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010646 Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. CHEBI:140311 FMNH(.)(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140311 GO:0034614 cellular response to reactive oxygen species biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034614 cellular response to reactive oxygen intermediate|cellular response to AOS|cellular response to ROS|cellular response to active oxygen species|cellular response to reactive oxidative species|cellular response to ROI Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals. CHEBI:57290 hydroxyacetone phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57290 GO:0010647 positive regulation of cell communication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010647 Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. CHEBI:140312 [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-N-(beta-D-Asp)-L-Lys-D-Ala-D-Ala)]n polyanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140312 GO:0010644 cell communication by electrical coupling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010644 The process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels. GO:0034615 GCH1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034615 GTP cyclohydrolase I complex A protein complex that possesses GTP cyclohydrolase I activity. In E. coli and human, the complex is a homodecamer, and monomers are catalytically inactive. GO:0034616 response to laminar fluid shear stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034616 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a laminar fluid shear stress stimulus. Laminar fluid flow is the force acting on an object in a system where the fluid is moving across a solid surface in parallel layers. As an example, laminar shear stress can be seen where blood flows against the luminal side of blood vessel walls. GO:0010645 regulation of cell communication by chemical coupling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010645 Any process that modulates the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels. CHEBI:140310 phenyl acetates biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140310 GO:0034617 tetrahydrobiopterin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034617 sapropterin binding|H4biopterin binding|BH4 binding Interacting selectively and non-covalently with a tetrahydrobiopterin, 5,6,7,8-tetrahydrobiopterin or a derivative thereof; tetrahydrobiopterins are enzyme cofactors that carry electrons in redox reactions. GO:0034618 arginine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034618 Arg binding|aminopentanoic acid binding Interacting selectively and non-covalently with 2-amino-5-(carbamimidamido)pentanoic acid. GO:0010648 negative regulation of cell communication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010648 Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. GO:0034619 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0034619 GO:0010649 regulation of cell communication by electrical coupling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010649 Any process that modulates the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels. CHEBI:57286 acetoacetyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57286 CHEBI:139319 S-disulfanyl-L-cysteine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139319 GO:0009650 UV protection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009650 ultraviolet tolerance|UV resistance|ultraviolet protection|ultraviolet resistance|UV tolerance Any process in which an organism or cell protects itself from ultraviolet radiation (UV), which may also result in resistance to repeated exposure to UV. CHEBI:57287 coenzyme A(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57287 GO:0009651 response to salt stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009651 salinity response|response to ionic osmotic stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. CHEBI:140317 phenyl sulfate oxoanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140317 CHEBI:57284 5-hydroxy-2-(4-methoxyphenyl)-4-oxo-4H-chromen-7-olate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57284 GO:0009652 thigmotropism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009652 Wikipedia:Thigmotropism The movement of an organism, or part of an organism, such as leaves or tendrils, in response to a touch stimulus, usually toward or away from it. GO:0009653 anatomical structure morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009653 Wikipedia:Morphogenesis morphogenesis|anatomical structure organization|embryogenesis and morphogenesis The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form. GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010642 negative regulation of platelet-derived growth factor receptor signalling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway. GO:0034610 oligodeoxyribonucleotidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034610 DNA oligonucleotidase activity Catalysis of the exonucleolytic cleavage of oligodeoxyribonucleotides to yield deoxyribonucleoside 5'-phosphates. GO:0010643 cell communication by chemical coupling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010643 The process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels. GO:0009654 photosystem II oxygen evolving complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009654 Wikipedia:Oxygen_evolving_complex oxygen evolving complex|OEC (PSII) complex A complex, composed of a cluster of manganese, calcium and chloride ions bound to extrinsic proteins, that catalyzes the splitting of water to O2 and 4 H+. In cyanobacteria there are five extrinsic proteins in OEC (PsbO, PsbP-like, PsbQ-like, PsbU and PsbV), while in plants there are only three (PsbO, PsbP and PsbQ). CHEBI:57283 N(alpha)-methyl-L-tryptophan zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57283 CHEBI:57280 N(6)-lipoyl-L-lysinium(1+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57280 GO:0009655 PSII associated light-harvesting complex II, core complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009655 PSII associated light-harvesting complex II, core complex, LHCIIa subcomplex|PSII associated light-harvesting complex II, core complex, LHCIIc subcomplex|PSII associated light-harvesting complex II, core complex, LHCIId subcomplex The pigment-protein complex primarily associated to PSII in higher plants, green algae and cyanobacteria that directly transfers electrons to the reaction center. GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010640 regulation of platelet-derived growth factor receptor signalling pathway Any process that modulates the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway. GO:0034611 oligoribonucleotidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034611 Reactome:R-HSA-9615042|Reactome:R-HSA-9009950 RNA oligonucleotidase activity Catalysis of the exonucleolytic cleavage of oligoribonucleotides to yield ribonucleoside 5'-phosphates. GO:0009656 PSII associated light-harvesting complex II, peripheral complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009656 Pigment-protein complex primarily associated to PSII in plants, green algae and cyanobacteria. Involved in state transitions that cause migration to PSI under certain environmental conditions such as high light. CHEBI:57281 N(6)-(S(8)-ammoniomethyldihydrolipoyl)-L-lysinium(2+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57281 GO:0034612 response to tumor necrosis factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034612 response to TNF Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus. GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010641 positive regulation of platelet-derived growth factor receptor signalling pathway Any process that increases the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway. CHEBI:140314 5'-triphosphoadenylyl-(2'->5')-adenosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_140314 GO:0009657 plastid organization biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0009657 plastid organisation|plastid organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plastid. UBERON:0004822 extrahepatic bile duct epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004822 epithelial tissue of extrahepatic bile duct|epithelium of extrahepatic bile duct|extrahepatic bile duct epithelial tissue An epithelium that is part of a extrahepatic bile duct [Automatically generated definition]. UBERON:0004823 intrahepatic bile duct epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004823 epithelial tissue of intrahepatic bile duct|epithelium of intrahepatic bile duct|intrahepatic bile duct epithelial tissue An epithelium that is part of a intrahepatic bile duct [Automatically generated definition]. GO:0009658 chloroplast organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009658 chloroplast organisation|chloroplast organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the chloroplast. GO:0009659 leucoplast organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009659 leucoplast organisation|leucoplast organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a leucoplast. A leucoplast is a colorless plastid involved in the synthesis of monoterpenes. UBERON:0004820 bile duct epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004820 epithelium of bile duct|epithelium of biliary duct|biliary duct epithelium Any epithelium that lines one of the bile ducts. UBERON:0004821 pulmonary alveolus epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004821 pulmonary alveolus epithelium|alveolus epithelium|epithelial tissue of alveolus|epithelium of alveolus|pulmonary alveolar epithelium|epithelium of pulmonary alveolus|alveolus epithelial tissue|alveolar epithelium The epithelial layer of the alveoli[MP]. The layer of cells covering the lining of the tiny air sacs at the end of the bronchioles[BTO]. CHEBI:57288 acetyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57288 CHEBI:57289 blasticidin S(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57289 UBERON:0004808 gastrointestinal system epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004808 epithelium of gastrointestinal system|epithelial tissue of gastrointestinal system|gastrointestinal system epithelial tissue|epithelial tissue of digestive system|digestive system epithelium|epithelium of digestive system|digestive system epithelial tissue An epithelium that is part of a digestive system [Automatically generated definition]. UBERON:0004809 salivary gland epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004809 epithelium of salivary gland|salivary gland epithelial tissue|epithelial tissue of salivary gland An epithelium that is part of a salivary gland [Automatically generated definition]. UBERON:0004806 vas deferens epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004806 deferent duct epithelium|vas deferens epithelial tissue|epithelium of deferent duct|epithelial tissue of deferent duct|deferent duct epithelial tissue|epithelial tissue of sperm duct|epithelium of vas deferen|epithelium of sperm duct|ductus deferens epithelium|epithelial tissue of vas deferen|vas deferen epithelial tissue|sperm duct epithelial tissue|sperm duct epithelium|epithelium of ductus deferens|epithelial tissue of ductus deferens|vas deferen epithelium|epithelial tissue of vas deferens|ductus deferens epithelial tissue|epithelium of vas deferens An epithelium that is part of a vas deferens [Automatically generated definition]. UBERON:0004807 respiratory system epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004807 epithelial tissue of respiratory system|epithelium of respiratory system|respiratory system epithelial tissue|apparatus respiratorius epithelium|epithelium of apparatus respiratorius|epithelial tissue of apparatus respiratorius|apparatus respiratorius epithelial tissue An epithelium that is part of a respiratory system [Automatically generated definition]. UBERON:0004804 oviduct epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004804 columnar epithelium of the fallopian tube|epithelium of fallopian tube|fallopian tube epithelium|epithelium of oviduct|epithelial tissue of oviduct|oviduct epithelial tissue|columnar epithelium of the oviduct|epithelium of uterine tube An epithelium that is part of a oviduct [Automatically generated definition]. UBERON:0004805 seminal vesicle epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004805 epithelium of seminal vesicle|epithelial tissue of seminal vesicle|seminal vesicle epithelial tissue|epithelium of seminal gland|seminal gland epithelium|epithelial tissue of seminal gland|seminal gland epithelial tissue An epithelium that is part of a seminal vesicle [Automatically generated definition]. UBERON:0004802 respiratory tract epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004802 respiratory epithelium|epithelium of respiratory tract|epithelial tissue of respiratory tract|respiratory tract epithelial tissue|airway epithelium the pseudostratified ciliated epithelium that lines much of the conducting portion of the airway, including part of the nasal cavity and larynx, the trachea, and bronchi UBERON:0004803 penis epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004803 epithelium of penis|epithelial tissue of penis|penis epithelial tissue An epithelium that is part of a penis [Automatically generated definition]. GO:0034602 oxoglutarate dehydrogenase (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034602 EC:1.2.1.-|KEGG_REACTION:R08549|MetaCyc:2OXOGLUTARATEDEH-RXN|RHEA:27786|Reactome:R-HSA-71401|Reactome:R-HSA-71037 Catalysis of the reaction: 2-oxoglutarate + CoA + NAD+ = succinyl-CoA + CO2 + NADH. GO:0010657 muscle cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010657 muscle cell apoptosis A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a muscle cell and result in its death. A muscle cell is a mature contractile cell, commonly known as a myocyte, that forms one of three kinds of muscle. GO:0010658 striated muscle cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010658 striated muscle cell apoptosis A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a striated muscle cell and result in its death. Striated muscle cells make up striated muscle fibers which are divided by transverse bands into striations. GO:0034603 pyruvate dehydrogenase [NAD(P)+] activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034603 Catalysis of the reaction: pyruvate + CoA + NAD(P)+ = acetyl-CoA + CO2 + NAD(P)H. CHEBI:140301 7-hydroxyisoflavones 7-O-beta-D-glucoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140301 GO:0034604 pyruvate dehydrogenase (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034604 RHEA:28042|KEGG_REACTION:R00209|MetaCyc:PYRUVDEH-RXN Catalysis of the reaction: pyruvate + CoA + NAD+ = acetyl-CoA + CO2 + NADH. GO:0010655 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010655 GO:0010656 negative regulation of muscle cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010656 negative regulation of muscle cell apoptosis Any process that decreases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death. GO:0034605 cellular response to heat biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034605 cellular response to heat stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism. GO:0034606 response to hermaphrodite contact biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034606 The response by the male to a hermaphrodite after initial contact following mate finding. The male stops forward locomotion, presses the ventral side of his tail against his partner's body, and begins moving backward along the hermaphrodite. Male response behavior is initiated when sensory neurons located in the rays of his tail contact a potential mate. GO:0034607 turning behavior involved in mating biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034607 turning behavior during mating The sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail. GO:0010659 cardiac muscle cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010659 cardiac muscle cell apoptosis A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a cardiac muscle cell and result in its death. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. GO:0034608 vulval location biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034608 Location, by the male, of his partner's vulva when backing along the ventral side of the hermaphrodite during mating. The male stops at the vulva, coordinates his movements to the hermaphrodite's, and positions his tail precisely over the vulva so that he may insert his spicules and ejaculate. GO:0034609 spicule insertion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034609 Insertion of the male copulatory spicules into the hermaphrodite. Spicule insertion behavior initiates when the male cloaca contacts the vulva. During most mating encounters, the spicule tips will prod the vulva continuously until they partially penetrate, which then causes the protractors to contract completely so that the spicules extend through the vulva. GO:0009670 triose-phosphate:phosphate antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009670 triose phosphate antiporter|triose phosphate translocator|TPT|dihydroxyacetone phosphate:phosphate antiporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: triose-phosphate(out) + phosphate(in) = triose-phosphate(in) + phosphate(out). GO:0009660 amyloplast organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009660 amyloplast organization and biogenesis|amyloplast organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an amyloplast. An amyloplast is a plastid whose main function is to synthesize and store starch. CHEBI:57275 dTDP-D-galactose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57275 CHEBI:140308 alpha-N-acetylneuraminyl-(2->3)-beta-D-galactoside(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140308 GO:0009661 chromoplast organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009661 chromoplast organization and biogenesis|chromoplast organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the chromoplast. A chromoplast is a plastid containing pigments other than chlorophyll, usually yellow and orange carotenoid pigments. CHEBI:57276 feruloyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57276 CHEBI:140309 alpha-N-acetylneuraminyl-(2->8)-alpha-N-acetylneuraminyl-(2->3)-beta-D-galactoside(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140309 GO:0010650 positive regulation of cell communication by electrical coupling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010650 Any process that increases the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels. CHEBI:57273 GDP-beta-L-fucose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57273 GO:0009662 etioplast organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009662 etioplast organisation|etioplast organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an etioplast. An etioplast is a plastid arrested in the development of chloroplasts from proplastids due to absence of light or low light conditions. CHEBI:140306 2'-hydroxygenistein(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140306 CHEBI:57274 3,5-dibromo-4-oxidobenzoate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57274 GO:0009663 plasmodesma organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009663 plasmodesmata organization and biogenesis|plasmodesma organization and biogenesis|plasmodesma organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasmodesma, a fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell. CHEBI:140304 beta-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->4)]-N-acetyl-beta-D-glucosaminide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140304 GO:0010653 negative regulation of cell communication by chemical coupling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010653 Any process that decreases the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels. GO:0009664 plant-type cell wall organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009664 cellulose and pectin-containing cell wall organization and biogenesis|cell wall organization and biogenesis|plant-type cell wall organisation|plant-type cell wall organization and biogenesis A process that results in the assembly and arrangement of constituent parts of the cellulose and pectin-containing cell wall, or in the disassembly of the cellulose and pectin-containing cell wall. This process is carried out at the cellular level. An example of this process is found in Arabidopsis thaliana. CHEBI:57271 indol-3-ylacetyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57271 GO:0009665 plastid inheritance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009665 The partitioning of plastids between daughter cells at cell division. GO:0010654 apical cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010654 The process in which the developmental fate of a cell becomes restricted such that it will develop into an apical cell. The apical cell is the upper cell formed after the first division of the zygote. CHEBI:140305 genistein 7-O-beta-D-glucoside(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140305 GO:0009666 plastid outer membrane organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009666 plastid outer membrane organization and biogenesis|plastid outer membrane organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the outer membrane of a plastid. CHEBI:140302 beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140302 GO:0034600 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0034600 GO:0010651 negative regulation of cell communication by electrical coupling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010651 Any process that decreases the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels. GO:0010652 positive regulation of cell communication by chemical coupling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010652 Any process that increases the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels. GO:0009667 plastid inner membrane organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009667 plastid inner membrane organization and biogenesis|plastid inner membrane organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the inner membrane of a plastid. GO:0034601 oxoglutarate dehydrogenase [NAD(P)+] activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034601 EC:1.2.1.52 Catalysis of the reaction: 2-oxoglutarate + CoA + NAD(P)+ = succinyl-CoA + CO2 + NAD(P)H. CHEBI:140303 beta-D-galactosyl-(1->4)-beta-D-glucoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140303 CHEBI:57270 N,N-dihydroxy-L-tyrosinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57270 GO:0009668 plastid membrane organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009668 plastid membrane organisation|plastid membrane organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of either of the lipid bilayers surrounding a plastid. UBERON:0004811 endometrium epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004811 epithelium of endometrium|epithelial tissue of endometrium|endometrium epithelial tissue|epithelium of tunica mucosa of endometrium|uterine epithelium An epithelium that is part of an endometrium [Automatically generated definition]. CHEBI:139323 coelenterazine 2-hydroperoxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139323 GO:0009669 sucrose:cation symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009669 sucrose:monovalent cation symporter activity|sucrose permease activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sucrose(out) + monovalent cation(out) = sucrose(in) + monovalent cation(in). CHEBI:139324 coelenterazine dioxetanone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139324 UBERON:0004810 nephron tubule epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004810 kidney tubule epithelium the cellular avascular layer of the renal tubule luminar surfaces CHEBI:57279 3-ammonio-2-oxopropyl phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57279 CHEBI:57277 3-(3-hydroxyphenyl)propanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57277 CHEBI:139321 S-(sulfosulfanyl)-L-cysteine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139321 CHEBI:57278 3-acylpyruvate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57278 GO:0010624 regulation of Schwann cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010624 Any process that modulates the frequency or rate of multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system. GO:0010625 positive regulation of Schwann cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010625 Any process that increases the frequency or rate of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system. GO:0010622 specification of ovule identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010622 The regionalization process in which the identity of an ovule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized. GO:0010623 programmed cell death involved in cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010623 programmed cell death involved in development|developmental programmed cell death The activation of endogenous cellular processes that result in the death of a cell as part of its development. GO:0010628 positive regulation of gene expression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010628 Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form. GO:0010629 negative regulation of gene expression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010629 Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form. GO:0010626 negative regulation of Schwann cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010626 Any process that decreases the frequency or extent of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system. GO:0010627 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010627 CHEBI:57264 4-fluoro-L-threonine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57264 CHEBI:57265 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57265 CHEBI:57262 3-sn-phosphatidyl-L-serine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57262 CHEBI:33299 alkaline earth molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33299 GO:0009630 gravitropism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009630 Wikipedia:Gravitropism geotropism The orientation of plant parts under the stimulation of gravity. CHEBI:57263 4-carboxylatomethylenebut-2-en-4-olide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57263 GO:0010620 negative regulation of transcription by transcription factor catabolism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010620 Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the catabolism of a sequence-specific DNA-binding transcription factor by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome. CHEBI:57260 2-methylbut-2-enoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57260 GO:0009631 cold acclimation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009631 Any process that increases freezing tolerance of an organism in response to low, nonfreezing temperatures. GO:0009632 obsolete freezing tolerance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009632 freezing tolerance OBSOLETE. (Was not defined before being made obsolete). CHEBI:57261 3,3',5'-triiodo-L-thyronine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57261 GO:0010621 negative regulation of transcription by transcription factor localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010621 negative regulation of transcription by transcription factor localisation Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the localization of a transcription factor. GO:0009633 obsolete drought tolerance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009633 drought tolerance OBSOLETE. (Was not defined before being made obsolete). GO:0009634 obsolete heavy metal sensitivity/resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009634 heavy metal sensitivity/resistance OBSOLETE. (Was not defined before being made obsolete). GO:0009635 response to herbicide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009635 herbicide susceptibility/resistance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a herbicide stimulus. Herbicides are chemicals used to kill or control the growth of plants. UBERON:0004801 cervix epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004801 cervical epithelium|cervical canal epithelial tissue|epithelium of cervix|cervical canal epithelium|cervix epithelial tissue An epithelium that is part of a uterine cervix [Automatically generated definition]. GO:0009636 response to toxic substance biolink:BiologicalProcess go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0009636 detoxification response|toxin resistance|toxin susceptibility/resistance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus. GO:0009637 response to blue light biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009637 response to blue light stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a blue light stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm. CHEBI:33292 fuel biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33292 GO:0009638 phototropism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009638 Wikipedia:Phototropism The movement of an organism, or part of an organism, in response to a light stimulus, usually toward or away from it. GO:0009639 response to red or far red light biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009639 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red or far red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs. CHEBI:57268 beta-L-fucose 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57268 CHEBI:57269 N,N'-diacetylchitobiosyldiphosphonatodolichol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57269 CHEBI:57266 (-)-usnic acid(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57266 CHEBI:33295 diagnostic agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33295 CHEBI:33296 alkali metal molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33296 CHEBI:57267 beta-D-fructofuranose 2-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57267 GO:0010635 regulation of mitochondrial fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010635 Any process that modulates the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment. GO:0010636 positive regulation of mitochondrial fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010636 Any process that increases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment. GO:0010633 negative regulation of epithelial cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010633 Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell migration. GO:0010634 positive regulation of epithelial cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010634 Any process that activates or increases the frequency, rate or extent of epithelial cell migration. GO:0010639 negative regulation of organelle organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010639 negative regulation of organelle organisation|negative regulation of organelle organization and biogenesis Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. GO:0010637 negative regulation of mitochondrial fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010637 Any process that decreases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment. GO:0010638 positive regulation of organelle organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization and biogenesis|positive regulation of organelle organisation Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. CHEBI:57253 (R)-2-benzylsuccinyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57253 CHEBI:57254 (R)-phenyllactoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57254 GO:0009640 photomorphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009640 Wikipedia:Photomorphogenesis plant development in response to light The control of plant growth, development, and differentiation by the duration and nature of light, independent of photosynthesis. CHEBI:57251 (3S)-3-hydroxy-L-aspartate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57251 CHEBI:57252 (E)-cinnamoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57252 GO:0009641 shade avoidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009641 Wikipedia:Shade_avoidance Shade avoidance is a set of responses that plants display when they are subjected to the shade of another plant. It often includes elongation, altered flowering time, increased apical dominance and altered partitioning of resources. Plants are able to distinguish between the shade of an inanimate object (e.g. a rock) and the shade of another plant due to the altered balance between red and far-red light in the shade of a plant; this balance between red and far-red light is perceived by phytochrome. GO:0009642 response to light intensity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009642 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light intensity stimulus. CHEBI:139304 2-hydroxyhexanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139304 GO:0010631 epithelial cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010631 The orderly movement of an epithelial cell from one site to another, often during the development of a multicellular organism. GO:0009643 photosynthetic acclimation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009643 light acclimatization|photoacclimation A response to light intensity in which exposure to medium-intensity light results in increased tolerance to high-intensity light. GO:0010632 regulation of epithelial cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010632 Any process that modulates the frequency, rate or extent of epithelial cell migration. GO:0009644 response to high light intensity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009644 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus. GO:0009645 response to low light intensity stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009645 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low light intensity stimulus. Low light intensity is defined as a level of electromagnetic radiation at or below 0.1 micromols/m2. GO:0010630 regulation of transcription, start site selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010630 Any process that modulates the frequency, rate or extent of the synthesis of either RNA on a template of DNA or DNA on a template of RNA by a mechanism that selects the start site along that template. GO:0009646 response to absence of light biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009646 response to darkness Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an absence of light stimuli. CHEBI:139300 (+)-jasmonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139300 CHEBI:139301 N-[(3R)-12-hydroxyjasmonyl]-L-isoleucine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139301 GO:0009647 skotomorphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009647 etiolation The control of plant growth, development, and differentiation in response to growth in darkness. GO:0009648 photoperiodism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009648 Wikipedia:Photoperiodism response to night length|response to day length|response to photoperiod Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a period of light or dark of a given length, measured relative to a particular duration known as the 'critical day length'. The critical day length varies between species. CHEBI:57259 2-deoxy-alpha-D-ribose 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57259 CHEBI:139302 N-[(3R)-jasmonyl]-L-isoleucine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139302 GO:0009649 entrainment of circadian clock biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009649 regulation of circadian rhythm phase The synchronization of a circadian rhythm to environmental time cues such as light. CHEBI:139303 2-hydroxybutanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139303 CHEBI:57257 1L-myo-inositol 1,2,3,4,6-pentakisphosphate(10-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57257 CHEBI:57258 2-amino-5-formylamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57258 CHEBI:57255 5-(2-carboxylatoethyl)-4-oxo-4,5-dihydro-1H-imidazol-5-ide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_57255 GO:0010608 posttranscriptional regulation of gene expression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010608 Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript. GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010609 mRNA localisation resulting in posttranscriptional regulation of gene expression|posttranscriptional regulation of gene expression by mRNA localisation|posttranscriptional regulation of gene expression by mRNA localization Any process that modulates the frequency, rate or extent of gene expression after the production of a mRNA transcript by its transport into, or maintainance in, a specific location within the cell. UBERON:0004859 eye gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004859 gland of eye|eye-associated gland A gland that is part of a eye. The eye is a compound unit which depending on the species may consist of an eyeballs plus associated ducts and integumentary structures. Eye glands therefore include the various types of lacrimal gland, the various types of apocrine and sebaceous glands associated with the eyelid. UBERON:0004857 skeletal muscle connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004857 skeletal muscle tissue connective tissue|portion of connective tissue of skeletal muscle tissue|skeletal muscle tissue portion of connective tissue|connective tissue of skeletal muscle|textus connectivus of skeletal muscle tissue|skeletal muscle tissue textus connectivus|skeletal muscle interstitum|skeletal muscle portion of connective tissue|textus connectivus of skeletal muscle|connective tissue of skeletal muscle tissue|skeletal muscle interstitial tissue|portion of connective tissue of skeletal muscle|skeletal muscle textus connectivus A connective tissue that surrounds a skeletal muscle tissue. GO:0010602 regulation of 1-aminocyclopropane-1-carboxylate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010602 Regulation of the chemical reactions and pathways involving 1-aminocyclopropane-1-carboxylate, the anion of 1-aminocyclopropane-1-carboxylic acid, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants. GO:0010603 regulation of cytoplasmic mRNA processing body assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010603 Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body. GO:0010600 regulation of auxin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010600 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth. GO:0010601 positive regulation of auxin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010601 Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth. GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010606 Any process that increases the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body. GO:0010607 negative regulation of cytoplasmic mRNA processing body assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010607 Any process that decreases the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body. GO:0010604 positive regulation of macromolecule metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010604 Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. GO:0010605 negative regulation of macromolecule metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010605 Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. CHEBI:33275 beta-tocotrienol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33275 CHEBI:33276 delta-tocotrienol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33276 CHEBI:33277 gamma-tocotrienol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33277 CHEBI:33279 vitamin D5 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33279 GO:0009610 response to symbiotic fungus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009610 response to symbiotic fungi Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a symbiotic fungus, a fungus living in close physical association with another organism. GO:0009611 response to wounding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009611 physiological response to wounding Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism. GO:0009612 response to mechanical stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009612 chemi-mechanical coupling|mechanical stimulus response Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus. GO:0009613 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009613 GO:0009614 obsolete disease resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009614 disease resistance OBSOLETE. (Was not defined before being made obsolete). UBERON:0004867 orbital cavity biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004867 orbit Anatomical cavity bounded by the orbital region of the cranium and forming the location of some or all of the eye. UBERON:0004864 vasculature of retina biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004864 vasa sanguinea retinae|set of blood vessels of retina|retina vasculature of camera-type eye|retinal blood vessels set|retinal blood vessels|retina vasculature|set of retinal blood vessels|retinal vasculature A vasculature that is part of a retina [Automatically generated definition]. GO:0009615 response to virus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009615 response to viruses Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus. CHEBI:57248 echinocandin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_57248 GO:0009616 RNAi-mediated antiviral immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009616 RNAi-mediated antiviral immunity|viral gene silencing in virus induced gene silencing|virus induced gene silencing|VIGS|virus-induced gene silencing|viral triggering of virus induced gene silencing RNA-mediated post-transcriptional gene silencing mechanism that protects against foreign organism invasion by restricting viral replication and dissemination. CHEBI:33270 alpha-tocotrienol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33270 UBERON:0004862 left lung alveolus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004862 alveolus of lobe of left lung|alveolus of left lung An alveolus that is part of a left lung [Automatically generated definition]. GO:0009617 response to bacterium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009617 response to bacteria Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium. GO:0009618 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009618 UBERON:0004863 thoracic sympathetic nerve trunk biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004863 sympathetic nerve trunk of thorax|thoracic sympathetic chain|nerve trunk of sympathetic nervous system of thorax|thorax sympathetic nerve trunk|nerve trunk of sympathetic part of autonomic division of nervous system of thorax|thoracic part of sympathetic trunk|thorax nerve trunk of sympathetic nervous system|sympathetic nervous system nerve trunk of thorax|thorax sympathetic nervous system nerve trunk|thorax nerve trunk of sympathetic part of autonomic division of nervous system|thoracic sympathetic trunk A sympathetic nerve trunk that is part of a thorax [Automatically generated definition]. CHEBI:33272 ketimine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33272 GO:0009619 obsolete resistance to pathogenic bacteria biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009619 resistance to pathogenic bacteria OBSOLETE. (Was not defined before being made obsolete). CHEBI:33273 polyatomic anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33273 UBERON:0004861 right lung alveolus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004861 alveolus of right lung An alveolus that is part of a right lung [Automatically generated definition]. GO:0010619 adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010619 glucose-sensing PKA pathway|activation of adenylate cyclase activity by glucose-triggered G-protein signaling pathway|activation of adenylate cyclase activity by glucose-triggered G-protein signalling pathway|activation of adenylate cyclase activity by glucose involved in G-protein signaling|adenylate cyclase-activating glucose-activated G-protein coupled receptor signaling pathway The series of molecular signals generated as a consequence of glucose binding to a G protein-coupled receptor, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP). UBERON:0004848 respiratory system arterial endothelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004848 artery endothelium of apparatus respiratorius|respiratory system artery endothelium|endothelium of artery of respiratory system|endothelium of artery of apparatus respiratorius|respiratory system endothelium of artery|artery endothelium of respiratory system|arterial endothelium of respiratory system|apparatus respiratorius artery endothelium|apparatus respiratorius endothelium of artery|arterial endothelium of apparatus respiratorius|apparatus respiratorius arterial endothelium An endothelium of artery that is part of a respiratory system [Automatically generated definition]. UBERON:0004849 respiratory system venous endothelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004849 respiratory system endothelium of vein|vein endothelium of respiratory system|venous endothelium of apparatus respiratorius|venous endothelium of respiratory system|vein endothelium of apparatus respiratorius|apparatus respiratorius vein endothelium|apparatus respiratorius endothelium of vein|apparatus respiratorius venous endothelium|endothelium of vein of apparatus respiratorius|respiratory system vein endothelium|endothelium of vein of respiratory system An endothelium of vein that is part of a respiratory system [Automatically generated definition]. GO:0010613 positive regulation of cardiac muscle hypertrophy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010613 Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division. GO:0010614 negative regulation of cardiac muscle hypertrophy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010614 Any process that decreases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division. GO:0010611 regulation of cardiac muscle hypertrophy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010611 Any process that modulates the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division. GO:0010612 regulation of cardiac muscle adaptation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010612 Any process that modulates the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. GO:0010617 circadian regulation of calcium ion oscillation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010617 circadian regulation of Ca2+ oscillation|circadian regulation of cytosolic calcium ion homeostasis|circadian regulation of cytosolic free calcium ion oscillation|circadian regulation of [Ca2+]cyt oscillation Any process that modulates the concentration of cytosolic free calcium ion [Ca2+]cyt with a regularity of approximately 24 hours. GO:0010618 aerenchyma formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010618 The process that gives rise to aerenchyma, parenchyma tissue containing particularly large intercellular spaces of schizogenous or lysigenous origin. This process pertains to the initial formation of a structure from unspecified parts. GO:0010615 positive regulation of cardiac muscle adaptation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010615 Any process that increases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. GO:0010616 negative regulation of cardiac muscle adaptation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010616 Any process that decreases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. CHEBI:33286 agrochemical biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33286 CHEBI:33287 fertilizer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33287 CHEBI:33288 rodenticide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33288 CHEBI:33289 avicide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33289 GO:0009620 response to fungus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009620 response to fungi Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus. GO:0010610 regulation of mRNA stability involved in response to stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010610 Any process that modulates the propensity of mRNA molecules to degradation that is part of a change in state or activity of a cell as a result of an exogenous disturbance. GO:0009621 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009621 GO:0009622 obsolete resistance to pathogenic fungi biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009622 resistance to pathogenic fungi OBSOLETE. (Was not defined before being made obsolete). GO:0009623 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009623 GO:0009624 response to nematode biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009624 response to nematodes Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a nematode. GO:0009625 response to insect biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009625 response to insects Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an insect. CHEBI:33280 molecular messenger biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33280 GO:0009626 plant-type hypersensitive response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009626 HR-PCD|plant hypersensitive response|HR The rapid, localized death of plant cells in response to invasion by a pathogen. GO:0009627 systemic acquired resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009627 Wikipedia:Systemic_acquired_resistance salicylic acid-dependent systemic resistance The salicylic acid mediated response to a pathogen which confers broad spectrum resistance. UBERON:0004854 gastrointestinal system mesentery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004854 mesentery of digestive system|digestive system mesentery|mesentery of gastrointestinal system A mesentery that is part of a digestive system [Automatically generated definition]. CHEBI:33281 antimicrobial agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33281 GO:0009628 response to abiotic stimulus biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate|goslim_plant|goslim_metagenomics http://purl.obolibrary.org/obo/GO_0009628 response to abiotic stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (not derived from living organisms) stimulus. UBERON:0004851 aorta endothelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004851 adult aorta endothelium|aortic endothelium|endothelium of aorta|endothelium of trunk of aortic tree|trunk of systemic arterial tree endothelium|endothelium of adult aorta|trunk of aortic tree endothelium|endothelium of trunk of systemic arterial tree the thin layer of flat cells that line the aorta and form a barrier between circulating blood in the lumen and the rest of the vessel wall CHEBI:33282 antibacterial agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33282 UBERON:0004852 cardiovascular system endothelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004852 endothelia|vascular endothelia An endothelium that is part of the cardiovascular system. GO:0009629 response to gravity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009629 response to gravitational stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus. CHEBI:33284 nutrient biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33284 UBERON:0004850 lymph node endothelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004850 endothelium of lymph node An endothelium that is part of a lymph node [Automatically generated definition]. CHEBI:33285 heteroorganic entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33285 UBERON:0004835 epididymis smooth muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004835 epididymis non-striated muscle|epididymis smooth muscle tissue|involuntary muscle of epididymis|epididymis involuntary muscle|non-striated muscle of epididymis|smooth muscle of epididymis|smooth muscle tissue of epididymis A portion of smooth muscle tissue that is part of a epididymis [Automatically generated definition]. GO:0044005 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044005 GO:0044006 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044006 GO:0044003 modulation by symbiont of host process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044003 modification by symbiont of host morphology or physiology|regulation by symbiont of host system process|modification by symbiont of host biological process|disruption by symbiont of host cell|modulation by symbiont of host system process The process in which a symbiont organism effects a change in the structure or processes of its host organism. GO:0044004 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044004 GO:0044001 migration in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044001 migration within host The directional movement of an organism from one place to another within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0044002 acquisition of nutrients from host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044002 The process that begins with the production and formation of structures and molecules in an organism that are required for the acquisition and utilization of nutrients from its host organism, and the ends with the acquirement of the nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0044000 movement in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044000 movement of symbiont in host|symbiont movement within host|movement of symbiont within host|movement within host|symbiont movement in host The process in which an organism or its progeny spreads from one location to another within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:33253 nucleon biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33253 CHEBI:33255 alkylmercury compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33255 CHEBI:33256 primary amide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33256 GO:0044009 obsolete viral transmission by vector biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044009 OBSOLETE. The transfer of virions by means of an organism (often an insect or other animal) in order to create new infection. CHEBI:33257 secondary amide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33257 GO:0044007 obsolete dissemination or transmission of symbiont from host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044007 dissemination or transmission of organism from host OBSOLETE. The movement of an organism from a host to another host or from a host to another place in the environment. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:33259 elemental molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33259 GO:0044008 obsolete dissemination or transmission of symbiont from host by vector biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044008 dissemination or transmission of organism from host by vector OBSOLETE. The movement of an organism from one host to another (or another place in the environment) by means of a third organism (often an insect or other animal). The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:33250 atom biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33250 CHEBI:33251 monoatomic hydrogen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33251 CHEBI:33252 atomic nucleus biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33252 CHEBI:47896 pyridine nucleoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47896 UBERON:0004829 urethra skeletal muscle tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004829 skeletal muscle tissue of urethra|urethral skeletal muscle|skeletal muscle of urethra|urethra skeletal muscle tissue|urethra skeletal muscle A portion of skeletal muscle tissue that is part of a urethra [Automatically generated definition]. CHEBI:47898 4'-epidoxorubicin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47898 UBERON:0004827 thyroid gland medulla biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004827 thyroid follicle medulla|thyroid medulla|medulla of thyroid gland|medulla of thyroid gland follicle|thyroid gland follicle medulla|medulla of thyroid follicle|medulla of thyroid A medulla that is part of a thyroid [Automatically generated definition]. CHEBI:47899 red chlorophyll catabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47899 GO:0044016 histone acetyltransferase activity (H3-K4 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044016 histone lysine N-acetyltransferase activity (H3-K4 specific) Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 4) = CoA + histone H3 N6-acetyl-L-lysine (position 4). GO:0044017 histone acetyltransferase activity (H3-K27 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044017 histone lysine N-acetyltransferase activity (H3-K27 specific) Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 27) = CoA + histone H3 N6-acetyl-L-lysine (position 27). GO:0044014 histone acetyltransferase activity (H2B-K5 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044014 histone lysine N-acetyltransferase activity (H2B-K5 specific) Catalysis of the reaction: acetyl-CoA + histone H2B L-lysine (position 5) = CoA + histone H2B N6-acetyl-L-lysine (position 5). GO:0044015 histone acetyltransferase activity (H2B-K12 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044015 histone lysine N-acetyltransferase activity (H2B-K12 specific) Catalysis of the reaction: acetyl-CoA + histone H2B L-lysine (position 12) = CoA + histone H2B N6-acetyl-L-lysine (position 12). GO:0044012 histone acetyltransferase activity (H2A-K9 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044012 histone lysine N-acetyltransferase activity (H2A-K9 specific) Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine (position 9) = CoA + histone H2A N6-acetyl-L-lysine (position 9). GO:0044013 H2B histone acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044013 H2B histone lysine N-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + histone H2B L-lysine = CoA + histone H2B N6-acetyl-L-lysine. CHEBI:47891 steroid acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47891 GO:0044010 single-species biofilm formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044010 bfp-dependent aggregation|bundle-forming pili-dependent aggregation|type IV pili-dependent aggregation|bundle-forming fimbriae-dependent aggregation|auto-aggregation|tfp-dependent aggregation A process in which planktonically growing microorganisms of the same species grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription. CHEBI:47892 4'-O-beta-D-glucosyl-cis-p-coumarate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47892 GO:0044011 single-species biofilm formation on inanimate substrate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044011 A process in which microorganisms of the same species attach to and grow on an inanimate surface such as a rock or pipe, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in an alteration in the phenotype of the organisms with respect to growth rate and gene transcription. CHEBI:47893 4-O-beta-D-glucosyl-4-coumarate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47893 CHEBI:33264 monoatomic oxygen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33264 CHEBI:33265 triatomic oxygen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33265 CHEBI:33266 diatomic nitrogen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33266 CHEBI:33267 elemental nitrogen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33267 GO:0044018 histone acetyltransferase activity (H3-K36 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044018 histone lysine N-acetyltransferase activity (H3-K36 specific) Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 36) = CoA + histone H3 N6-acetyl-L-lysine (position 36). GO:0009600 detection of nematode biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009600 perception of nematode The series of events in which a stimulus from a nematode is received and converted into a molecular signal. GO:0009601 detection of insect biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009601 perception of insect The series of events in which a stimulus from an insect is received and converted into a molecular signal. GO:0044019 histone acetyltransferase activity (H3-K72 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044019 histone lysine N-acetyltransferase activity (H3-K72 specific) Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 72) = CoA + histone H3 N6-acetyl-L-lysine (position 72). GO:0009602 detection of symbiont biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009602 perception of symbiont|recognition of symbiont The series of events in which a stimulus from a symbiont (an organism living in close physical association with an organism of a different species) is received and converted into a molecular signal. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. UBERON:0004833 lip skeletal muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004833 skeletal muscle tissue of lip|lip skeletal muscle tissue|skeletal muscle of lip A portion of skeletal muscle tissue that is part of a lip [Automatically generated definition]. GO:0009603 detection of symbiotic fungus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009603 perception of symbiotic fungi|perception of symbiotic fungus|detection of symbiotic fungi The series of events in which a stimulus from a symbiotic fungus, a fungus living in close physical association with another organism, is received and converted into a molecular signal. UBERON:0004834 hepatic duct smooth muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004834 Smooth muscle tissue in all or part of a hepatic duct. GO:0009604 detection of symbiotic bacterium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009604 detection of symbiotic bacteria|perception of symbiotic bacteria|perception of symbiotic bacterium The series of events in which a stimulus from a symbiotic bacterium, a bacterium living in close physical association with another organism, is received and converted into a molecular signal. UBERON:0004831 esophagus skeletal muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004831 skeletal muscle of esophagus|esophagus skeletal muscle tissue A portion of skeletal muscle tissue that is part of a esophagus [Automatically generated definition]. UBERON:0004832 anal region skeletal muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004832 skeletal muscle tissue of anal region|skeletal muscle of anal part of perineum|anal triangle skeletal muscle tissue|skeletal muscle of anal region|skeletal muscle tissue of anal triangle|anal part of perineum skeletal muscle|anal region skeletal muscle tissue|skeletal muscle of anal triangle|anal part of perineum skeletal muscle tissue|skeletal muscle tissue of anal part of perineum|anal triangle skeletal muscle A portion of skeletal muscle tissue that is part of an anal region [Automatically generated definition]. GO:0009605 response to external stimulus biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate|goslim_plant|goslim_drosophila http://purl.obolibrary.org/obo/GO_0009605 response to environmental stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus. GO:0009606 tropism biolink:BiologicalProcess go-plus goslim_plant http://purl.obolibrary.org/obo/GO_0009606 Wikipedia:Tropism The movement of an organism, or part of an organism, in response to an external source of stimulus, usually toward or away from it. CHEBI:33260 elemental hydrogen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33260 UBERON:0004830 respiratory system skeletal muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004830 skeletal muscle of respiratory system|skeletal muscle tissue of apparatus respiratorius|skeletal muscle tissue of respiratory system|skeletal muscle of apparatus respiratorius|respiratory system skeletal muscle tissue A portion of skeletal muscle tissue that is part of a respiratory system [Automatically generated definition]. GO:0009607 response to biotic stimulus biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate|goslim_plant|goslim_metagenomics http://purl.obolibrary.org/obo/GO_0009607 response to biotic stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism. CHEBI:33261 organosulfur compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33261 GO:0009608 response to symbiont biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009608 response of host to symbiont Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a symbiont, an organism living with an organism of a different species in close physical association. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:33262 elemental oxygen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33262 CHEBI:33263 diatomic oxygen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33263 GO:0009609 response to symbiotic bacterium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009609 response to symbiotic bacteria Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a symbiotic bacterium, a bacterium living in close physical association with another organism. CHEBI:140391 (3R)-3-{[(3R)-3-{[(3R)-3-{[(3R)-3-{[(3R)-3-hydroxybutanoyl]oxy}butanoyl]oxy}butanoyl]oxy}butanoyl]oxy}butanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_140391 GO:0019063 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019063 GO:0019064 fusion of virus membrane with host plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019064 VZ:987 viral envelope fusion|viral envelope fusion with host membrane|viral envelope fusion with host plasma membrane|viral envelope fusion with host cell membrane|viral penetration via membrane fusion|viral entry into host cell via membrane fusion with the plasma membrane|viral-cell fusion molecule activity Fusion of a viral membrane with the host cell membrane during viral entry. Results in release of the virion contents into the cytoplasm. CHEBI:72840 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72840 CHEBI:140392 (3R)-3-hydroxybutanoic acid oligomer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_140392 GO:0019061 uncoating of virus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019061 viral uncoating The process by which an incoming virus is disassembled in the host cell to release a replication-competent viral genome. CHEBI:72841 1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72841 GO:0019062 virion attachment to host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019062 VZ:956 viral attachment to host cell|viral absorption|virion attachment to host cell surface receptor The process by which a virion protein binds to molecules on the host cellular surface or host cell surface projection. CHEBI:140390 (3R)-3-{[(3R)-3-{[(3R)-3-{[(3R)-3-hydroxybutanoyl]oxy}butanoyl]oxy}butanoyl]oxy}butanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_140390 GO:0019060 intracellular transport of viral protein in host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019060 intracellular transport of viral proteins in host cell|intracellular viral protein transport|viral capsid transport in host cell nucleus|nuclear viral capsid transport|intracellular transport of viral capsid in host cell|cytoplasmic viral capsid transport|intracellular viral capsid transport|viral capsid transport in host cell cytoplasm|intracellular transport of viral capsid protein in host cell The directed movement of a viral protein within the host cell. CHEBI:72845 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72845 CHEBI:140399 specialised pro-resolving mediator biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_140399 CHEBI:140395 poly(nucleoside 5'-monophosphate) polyanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140395 GO:0034693 U11/U12 snRNP biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034693 snRNP U11/U12|18S U11/U12 snRNP A ribonucleoprotein complex that is formed by the association of the U11 and U12 small nuclear ribonucleoproteins. GO:0034694 response to prostaglandin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034694 response to prostaglandin stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin stimulus. GO:0034695 response to prostaglandin E biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034695 response to prostaglandin E stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus. GO:0034696 response to prostaglandin F biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034696 response to prostaglandin F stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin F stimulus. GO:0034697 response to prostaglandin I biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034697 response to prostaglandin I stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin I stimulus. GO:0034698 response to gonadotropin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034698 response to gonadotropin stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus. GO:0034699 response to luteinizing hormone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034699 response to luteinizing hormone stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a luteinizing hormone stimulus. CHEBI:139399 N-hexadecanoyl-O-(1-octadecanoyl-sn-glycero-3-phospho)-L-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139399 GO:0019058 viral life cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019058 viral assembly, maturation, egress, and release|lytic viral life cycle|viral replication|viral infectious cycle A set of processes which all viruses follow to ensure survival; includes attachment and entry of the virus particle, decoding of genome information, translation of viral mRNA by host ribosomes, genome replication, and assembly and release of viral particles containing the genome. GO:0019059 obsolete initiation of viral infection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019059 initiation of viral infection OBSOLETE. The set of processes involved in the start of virus infection of cells. GO:0019056 modulation by virus of host transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019056 viral perturbation of host cell transcription|modification by virus of host transcription Any process in which a virus modulates the frequency, rate or extent of its host's transcription. GO:0019057 modulation by virus of host translation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019057 regulation of host translation by virus|regulation of host mRNA translation by virus|modulation of host translation by virus|host cell protein synthesis shutoff|viral host shutoff protein|viral perturbation of host cell mRNA translation|regulation of translation in host by virus|modification by virus of host cell mRNA translation|host cell shutoff Any process in which a virus modulates the frequency, rate or extent of translation of host mRNA. GO:0034690 integrin alphaD-beta2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034690 alphaD-beta2 integrin complex|Itgad-Itgb2 complex An integrin complex that comprises one alphaD subunit and one beta2 subunit. CHEBI:139396 CDP-4-dehydro-6-deoxy-alpha-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139396 GO:0019054 modulation by virus of host cellular process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019054 regulation of cellular process in host by virus|regulation by virus of host cellular process|regulation of host cellular process by virus|modification by virus of host cellular process|modulation of cellular process in host by virus|modulation by virus of host process|viral host cell process manipulation The process in which a virus effects a change in the processes and activities of its host organism. GO:0034691 integrin alphaE-beta7 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034691 Itgae-Itgb7 complex An integrin complex that comprises one alphaE subunit and one beta7 subunit. CHEBI:139397 N-hexadecanoyl-O-(1-octadecanoyl-2-oleoyl-sn-glycero-3-phospho)-L-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139397 GO:0019055 modification by virus of host cell cycle regulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019055 viral perturbation of cell cycle regulation Interactions, directly with the host cell macromolecular machinery, to allow a virus to modulate the rate of the host cell cycle to facilitate virus replication. GO:0034692 E.F.G complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034692 A protein complex that comprises three core spliceosomal proteins, designated E, F, and G. Formation of the E.F.G complex is essential but not sufficient for the formation of a stable U1 snRNP complex. CHEBI:139398 N-acyl-O-(3-sn-phosphatidyl)-L-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139398 GO:0019074 viral RNA genome packaging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019074 The packaging of viral RNA (single-stranded or double-stranded) into a nucleocapsid. CHEBI:140380 an aldono-1,5-lactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140380 CHEBI:72850 icosadienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72850 GO:0019075 virus maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019075 bacteriophage maturation|viral maturation The refolding and structural rearrangements of virion parts to transition from the intermediate virion to the more mature virion. Maturation usually involves proteolysis events and changes in the folding of the virion proteins. Can occur inside the host cell or after release. GO:0019072 viral genome packaging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019072 The encapsulation of the viral genome within the capsid. CHEBI:72852 EpETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72852 CHEBI:72853 17(18)-EpETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72853 GO:0019073 viral DNA genome packaging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019073 The packing of viral DNA into a capsid. GO:0019070 viral genome maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019070 The processes involved in creating a mature, stable viral genome. Begins after genome replication with a newly synthesized nucleic acid and ends when the genome is ready to be packaged. Includes the addition of proteins to the newly synthesized genome, and DNA repair processes. CHEBI:72854 EC 1.13.11.52 (indoleamine 2,3-dioxygenase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72854 CHEBI:72855 (4Z,7Z,10Z,13Z,19Z)-16,17-epoxydocosapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72855 GO:0019071 viral DNA cleavage involved in viral genome maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019071 The cleavage of viral DNA into singular functional units. CHEBI:72857 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72857 CHEBI:140388 (3R)-3-{[(3R)-3-{[(3R)-3-hydroxybutanoyl]oxy}butanoyl]oxy}butanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_140388 CHEBI:72858 1-hexadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72858 CHEBI:72859 1,2-dihexadecanoyl-sn-glycerol-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72859 CHEBI:140384 (3R)-3-{[(3R)-3-{[(3R)-3-{[(3R)-3-hydroxybutanoyl]oxy}butanoyl]oxy}butanoyl]oxy}butanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140384 CHEBI:140385 (3R)-3-{[(3R)-3-{[(3R)-3-hydroxybutanoyl]oxy}butanoyl]oxy}butanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140385 CHEBI:140383 (3R)-3-{[(3R)-3-{[(3R)-3-{[(3R)-3-{[(3R)-3-hydroxybutanoyl]oxy}butanoyl]oxy}butanoyl]oxy}butanoyl]oxy}butanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140383 GO:0034682 integrin alphav-beta1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034682 alphav-beta1 integrin complex|ITGAV-ITGB1 complex An integrin complex that comprises one alphav subunit and one beta1 subunit. GO:0034683 integrin alphav-beta3 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034683 ITGAV-ITGB3 complex|alphav-beta3 integrin complex An integrin complex that comprises one alphav subunit and one beta3 subunit. GO:0034684 integrin alphav-beta5 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034684 alphav-beta5 integrin complex|ITGAV-ITGB5 complex An integrin complex that comprises one alphav subunit and one beta5 subunit. GO:0034685 integrin alphav-beta6 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034685 alphav-beta6 integrin complex|ITGAV-ITGB6 complex An integrin complex that comprises one alphav subunit and one beta6 subunit. GO:0034686 integrin alphav-beta8 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034686 ITGAV-ITGB8 complex|alphav-beta8 integrin complex An integrin complex that comprises one alphav subunit and one beta8 subunit. GO:0034687 integrin alphaL-beta2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034687 alphaL-beta2 integrin complex|Itgal-Itgb2 complex An integrin complex that comprises one alphaL subunit and one beta2 subunit. GO:0034688 integrin alphaM-beta2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034688 alphaM-beta2 integrin complex|Itgam-Itgb2 complex An integrin complex that comprises one alphaM subunit and one beta2 subunit. GO:0034689 integrin alphaX-beta2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034689 alphaX-beta2 integrin complex|Itgax-Itgb2 complex An integrin complex that comprises one alphaX subunit and one beta2 subunit. GO:0019069 viral capsid assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019069 The assembly of a virus capsid from its protein subunits. GO:0019067 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019067 GO:0019068 virion assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019068 virus assembly|bacteriophage assembly|phage assembly|viral particle assembly|virion organization|virion assembly and maintenance|virus particle assembly|viral assembly A late phase of the viral life cycle during which all the components necessary for the formation of a mature virion collect at a particular site in the cell and the basic structure of the virus particle is formed. GO:0019065 receptor-mediated endocytosis of virus by host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019065 viral receptor mediated endocytosis|receptor mediated endocytosis of virus particle by host|receptor mediated endocytosis by host of virus particle|receptor-mediated endocytosis of virus by host|virus receptor-mediated endocytosis by host|viral entry into host cell via receptor-mediated endocytosis|receptor mediated endocytosis of virus by host Any receptor-mediated endocytosis that is involved in the uptake of a virus into a host cell; successive instances of virus endocytosis result in the accumulation of virus particles within the cell. GO:0034680 integrin alpha10-beta1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034680 ITGA10-ITGB1 complex|alpha10-beta1 integrin complex An integrin complex that comprises one alpha10 subunit and one beta1 subunit. GO:0034681 integrin alpha11-beta1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034681 ITGA11-ITGB1 complex|alpha11-beta1 integrin complex An integrin complex that comprises one alpha11 subunit and one beta1 subunit. GO:0019066 obsolete translocation of virus into host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019066 viral translocation|translocation of virus into host cell OBSOLETE. The translocation of an entire virus particle across the host cell plasma membrane. GO:0020030 infected host cell surface knob biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0020030 Protrusion that develops in the plasma membrane of a parasitized erythrocyte. An example of this component is found in Plasmodium species. GO:0019041 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019041 GO:0019042 viral latency biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019042 phage lysogeny|viral dormancy|latent virus infection The process by which, after initial infection, a virus lies dormant within a cell and viral production ceases. The process ends when the virus switches from latency and starts to replicate. GO:0020031 polar ring of apical complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0020031 anterior polar ring of apical complex|upper polar ring of apical complex An electron dense ring at the most anterior position of the apical complex, from which the conoid fibers originate; formed during an invasive life cycle stage of an apicomplexan parasite. GO:0020032 basal ring of apical complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0020032 preconoidal ring of apical complex|posterior polar ring of apical complex|lower polar ring of apical complex An electron dense ring at the most posterior position of the apical complex, from which the subpellicular microtubules originate; formed during an invasive life cycle stage of an apicomplexan parasite. GO:0020033 antigenic variation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0020033 Wikipedia:Antigenic_variation surface antigen variation Any process involved in the biological strategy of changing antigenic determinants on the surface that are exposed to another organism's immune system. CHEBI:72864 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72864 GO:0019040 obsolete viral host shutoff protein biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019040 viral host shutoff protein OBSOLETE. (Was not defined before being made obsolete). GO:0020034 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0020034 CHEBI:72865 (5Z,8Z,11Z)-icosatrienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72865 GO:0020035 cytoadherence to microvasculature, mediated by symbiont protein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0020035 parasite-protein-mediated cytoadherence to microvasculature|cytoadherence to microvasculature, mediated by parasite protein|symbiont-protein-mediated cytoadherence to microvasculature|heterophilic cell adhesion involved in cytoadherence to microvasculature, mediated by parasite protein The adherence of symbiont-infected erythrocytes to microvascular endothelium via symbiont proteins embedded in the membrane of the erythrocyte. GO:0020036 Maurer's cleft biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0020036 Maurers cleft A disk-like structure that appears at the periphery of a red blood cell infected by an apicomplexan parasite, characterized by a translucent lumen and an electron-dense coat of variable thickness; often appears to be tethered to the host cell membrane by fibrous connections with the erythrocyte cytoskeleton. GO:0020037 heme binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0020037 haem binding Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring. CHEBI:72868 dihydroxyicosatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72868 GO:0034679 integrin alpha9-beta1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034679 alpha9-beta1 integrin complex|ITGA9-ITGB1 complex An integrin complex that comprises one alpha9 subunit and one beta1 subunit. CHEBI:140377 (2S)-flavan-4-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140377 CHEBI:140374 3-diphospho-1D-myo-inositol 1,2,4,5,6-pentakisphosphate(13-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140374 CHEBI:140371 N(4)-[6-phospho-alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-glycan]-L-asparagine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140371 CHEBI:140372 3,5-bis(diphospho)-1D-myo-inositol 1,2,4,6-tetrakisphosphate(13-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140372 GO:0034671 retinoic acid receptor signaling pathway involved in pronephros anterior/posterior pattern specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034671 retinoic acid receptor signalling pathway involved in pronephros anterior-posterior patterning|retinoic acid receptor signaling pathway involved in pronephric kidney anterior/posterior pattern specification The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that results in the spatial identity of regions along the anterior-posterior axis of the pronephros. GO:0034672 anterior/posterior pattern specification involved in pronephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034672 anterior/posterior pattern specification involved in pronephric kidney development The developmental process that results in the creation of defined areas or spaces within the pronephros along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate. GO:0034673 inhibin-betaglycan-ActRII complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034673 A protein complex that consists of inhibin, type III transforming growth factor beta receptor (also known as betaglycan), and the type II activin receptor ActRII. The complex is thought to negatively regulate the activity of activin B. GO:0034674 integrin alpha5-beta1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034674 ITGA5-ITGB1 complex|VLA-5 complex|alpha5-beta1 integrin complex An integrin complex that comprises one alpha5 subunit and one beta1 subunit. GO:0034675 integrin alpha6-beta1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034675 ITGA6-ITGB1 complex|alpha6-beta1 integrin complex|VLA-6 complex An integrin complex that comprises one alpha6 subunit and one beta1 subunit. GO:0034676 integrin alpha6-beta4 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034676 ITGA6-ITGB4 complex|alpha6-beta4 integrin complex An integrin complex that comprises one alpha6 subunit and one beta4 subunit. GO:0034677 integrin alpha7-beta1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034677 ITGA7-ITGB1 complex|alpha7-beta1 integrin complex An integrin complex that comprises one alpha7 subunit and one beta1 subunit. CHEBI:140379 an aldopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140379 GO:0034678 integrin alpha8-beta1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034678 ITGA8-ITGB1 complex|alpha8-beta1 integrin complex An integrin complex that comprises one alpha8 subunit and one beta1 subunit. GO:0019038 obsolete provirus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019038 Wikipedia:Provirus OBSOLETE. The name given to a viral genome after it has been integrated into the host genome; particularly applies to retroviruses and is a required part of the retroviral replication cycle. GO:0020038 subpellicular network biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0020038 A mechanically stable cytoskeletal structure associated with the cytoplasmic face of the pellicle and surrounding the microtubule-based cytoskeleton. GO:0020039 pellicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0020039 The structure enclosing certain parasite cells such as certain apicomplexa and Euglenozoa; consists of the cell membrane with its associated infrastructure of microtubules, microfilaments and other organelles. GO:0019039 obsolete viral-cell fusion molecule activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019039 viral-cell fusion molecule activity OBSOLETE. (Was not defined before being made obsolete). GO:0019036 viral transcriptional complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019036 Specific locations and structures in the virus infected cell involved in transcribing the viral genome. GO:0019037 viral assembly intermediate biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019037 Specific locations and structures in the virus infected cell involved in assembling new virions. GO:0019034 viral replication complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019034 Specific locations and structures in the virus infected cell involved in replicating the viral genome. GO:0019035 viral integration complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019035 pre-integration complex|PIC A nucleoprotein complex containing viral genetic material and associated viral and host proteins, which is capable of inserting a viral genome into a host genome. GO:0019032 obsolete viral glycoprotein biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019032 viral glycoprotein OBSOLETE. (Was not defined before being made obsolete). CHEBI:139375 (R)-2-hydroxyhexadecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139375 GO:0019033 viral tegument biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019033 Wikipedia:Viral_tegument A structure lying between the capsid and envelope of a virus, varying in thickness and often distributed asymmetrically. GO:0034670 chemotaxis to arachidonic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034670 The directed movement of a motile cell or organism in response to the presence of arachidonic acid. CHEBI:139376 2-hydroxy-3-methyldodecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139376 CHEBI:72860 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72860 GO:0019052 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019052 GO:0019053 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019053 GO:0020020 food vacuole biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0020020 digestive vacuole Vacuole within a parasite used for digestion of the host cell cytoplasm. An example of this component is found in the Apicomplexa. CHEBI:139392 3-methyldodecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139392 GO:0020021 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0020021 GO:0019050 suppression by virus of host apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019050 suppression by virus of host apoptosis|negative regulation by virus of host apoptosis|negative regulation of apoptosis by virus|suppression of apoptosis in host by virus Any viral process that inhibits apoptosis of infected host cells, facilitating prolonged cell survival during viral replication. GO:0020022 acidocalcisome biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0020022 volutin granule|metachromatic granule|polyphosphate vacuole An electron-dense acidic membrane-bounded organelle which contains a matrix of pyrophosphate and polyphosphates with bound calcium and other cations. GO:0019051 induction by virus of host apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019051 activation by virus of host apoptosis|activation by virus of host apoptotic programmed cell death|activation of apoptosis in host by virus|induction by virus of host apoptosis|induction by virus of host apoptotic programmed cell death|induction of apoptosis in host by virus The set of viral processes that induce an apoptotic process in infected host cells, facilitating release and spread of progeny virions. CHEBI:139394 alpha-D-galactosyl ditrans,octacis-undecaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139394 GO:0020023 kinetoplast biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0020023 Wikipedia:Kinetoplast A sub-structure within the large single mitochondrion of kinetoplastid parasites and which is closely associated with the flagellar pocket and basal body of the flagellum. GO:0020025 subpellicular microtubule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0020025 Singlet microtubule that lie underneath the inner membrane pellicle complex and emanate from the basal ring of the conoid. GO:0020026 merozoite dense granule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0020026 dense body Electron-dense organelle with a granular internal matrix found throughout the merozoite life cycle stage of apicomplexan parasites; contains proteins destined to be secreted into the parasitophorous vacuole following parasite invasion of a host cell. GO:0034668 integrin alpha4-beta1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034668 alpha4-beta1 integrin complex|VLA-4 complex|ITGA4-ITGB1 complex An integrin complex that comprises one alpha4 subunit and one beta1 subunit. GO:0034669 integrin alpha4-beta7 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034669 ITGA4-ITGB7 complex|alpha4-beta7 integrin complex An integrin complex that comprises one alpha4 subunit and one beta7 subunit. GO:0034660 ncRNA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034660 ncRNA metabolism The chemical reactions and pathways involving non-coding RNA transcripts (ncRNAs). GO:0034661 ncRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034661 ncRNA breakdown|ncRNA catabolism|ncRNA degradation The chemical reactions and pathways resulting in the breakdown of non-coding RNA transcripts (ncRNAs). Includes the breakdown of cryptic unstable transcripts (CUTs). GO:0034662 CFTR-NHERF-ezrin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034662 A protein complex that contains ezrin, Na+/H+ exchanger regulatory factor (NHERF, also called EBP50), and two copies of the cystic fibrosis transmembrane conductance regulator (CFTR). The CFTR molecules interact with NHERF via their cytoplasmic tail domains; the complex is thought to link the CFTR channel to the actin cytoskeleton and contribute to the regulation of channel activity. GO:0034663 endoplasmic reticulum chaperone complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034663 endoplasmic reticulum network complex|ER network complex|ER chaperone complex A protein complex that is located in the endoplasmic reticulum and is composed of chaperone proteins, including BiP, GRP94; CaBP1, protein disulfide isomerase (PDI), ERdj3, cyclophilin B, ERp72, GRP170, UDP-glucosyltransferase, and SDF2-L1. GO:0034664 Ig heavy chain-bound endoplasmic reticulum chaperone complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034664 Ig heavy chain-bound ER chaperone complex|immunoglobulin heavy chain-bound endoplasmic reticulum chaperone complex A protein complex that is located in the endoplasmic reticulum (ER) and is formed by the association of an immunoglobulin heavy chain with the proteins of the ER chaperone complex; the latter include BiP, GRP94; CaBP1, protein disulfide isomerase (PDI), ERdj3, cyclophilin B, ERp72, GRP170, UDP-glucosyltransferase, and SDF2-L1. GO:0034665 integrin alpha1-beta1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034665 alpha1-beta1 integrin complex|VLA-1 complex|ITGA1-ITGB1 complex An integrin complex that comprises one alpha1 subunit and one beta1 subunit. GO:0034666 integrin alpha2-beta1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034666 ITGA2-ITGB1 complex|VLA-2 complex An integrin complex that comprises one alpha2 subunit and one beta1 subunit. CHEBI:140369 N(4)-[6-(N-acetyl-alpha-D-glucosaminyl-1-phospho)-alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-glycan]-L-asparagine residue(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140369 GO:0034667 integrin alpha3-beta1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034667 ITGA3-ITGB1 complex|alpha3-beta1 integrin complex|VLA-3 complex An integrin complex that comprises one alpha3 subunit and one beta1 subunit. GO:0019049 mitigation of host defenses by virus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019049 evasion of host defenses by virus|viral host defence evasion|evasion or tolerance of host defenses by virus|viral host defense evasion A process by which a virus avoids or tolerates the effects of its host organism's defenses. Host defenses may be induced by the presence of the virus or may be preformed (e.g. physical barriers). The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0020027 hemoglobin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0020027 haemoglobin metabolism|haemoglobin metabolic process|hemoglobin metabolism The chemical reactions and pathways involving hemoglobin, including its uptake and utilization. GO:0020028 endocytic hemoglobin import into cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0020028 endocytic hemoglobin import|hemoglobin uptake|haemoglobin uptake The directed movement of hemoglobin into a cell by receptor-mediated endocytosis. GO:0020029 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0020029 GO:0019047 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019047 GO:0019048 modulation by virus of host process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019048 VZ:886 modulation by virus of host morphology or physiology|viral-host process|modulation by virus of host anatomy or process|disruption by virus of host cell|host-virus interaction|virus-host process|viral interaction with host|modulation by virus of host anatomical structure or process|virus-host interaction The process in which a virus effects a change in the structure or processes of its host organism. GO:0019045 latent virus replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019045 Any process required for latent viral replication in a cell. GO:0019046 release from viral latency biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019046 The process by which a virus begins to replicate following a latency replication decision (switch). GO:0019043 establishment of viral latency biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019043 lysogenic commitment|phage lysogeny A process by which a virus establishes a latent state within its host, either as an integrated provirus within the host genome or as an episome, where viral genome remains in the cytoplasm or nucleus as distinct objects. GO:0019044 maintenance of viral latency biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019044 prophage maintenance|provirus maintenance|latent virus maintenance The perpetuation of a latent state, generally by repressing the viruses own lytic genes expression and ensuring expression of viral genes which function to keep the viral genome from being detected by the host defense mechanisms. GO:0019020 obsolete multipartite viral genome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019020 OBSOLETE. A segmented viral genome consisting of more than three sub-genomic nucleic acids but each nucleic acid is packaged into a different virion. GO:0020010 conoid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0020010 A spiral cytoskeletal structure located at the apical end of the apical complex in some apicomplexan parasites. Fibers form a left-handed spiral, and are comprised of tubulin protofilaments organized in a ribbon-like structure that differs from the conventional tubular structure characteristic of microtubules. GO:0020011 apicoplast biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0020011 Wikipedia:Apicoplast The plastid organelle found in apicomplexans. GO:0020012 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0020012 GO:0020013 modulation by symbiont of host erythrocyte aggregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0020013 Wikipedia:Rosetting rosetting Any process in which a symbiont organism modulates the frequency, rate or extent of erythrocyte aggregation in its host organism, e.g. the binding of parasite-infected erythrocytes to uninfected erythrocytes. GO:0020014 schizogony biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0020014 Wikipedia:Protozoal_merogony Cell division by multiple fission in which nuclei and other organelles in the parent cell divide repeatedly and move to the cell periphery before internal membranes develop around them, producing a large number of daughter cells simultaneously. GO:0020015 glycosome biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0020015 Wikipedia:Glycosome A membrane-bounded organelle found in organisms from the order Kinetoplastida that houses the enzymes of glycolysis. GO:0034657 GID complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034657 A protein complex with ubiquitin ligase activity that is involved in proteasomal degradation of fructose-1,6-bisphosphatase (FBPase) and phosphoenolpyruvate carboxykinase during the transition from gluconeogenic to glycolytic growth conditions. In S. cerevisiae, the GID (Glucose Induced degradation Deficient) complex consists of Vid30p, Rmd5p, Vid24p, Vid28p, Gid7p, Gid8p, and Fyv10p. CHEBI:82207 (4S)-7-hydroxy-4-isopropenyl-7-methyloxepan-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82207 GO:0034658 isopropylmalate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034658 Enables the transfer of isopropylmalate from one side of a membrane to the other. CHEBI:140356 7-methoxyisoflavones biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140356 GO:0010688 negative regulation of ribosomal protein gene transcription by RNA polymerase II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010688 negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II. CHEBI:82204 (4R)-7-hydroxy-4-isopropenyl-7-methyloxepan-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_82204 GO:0034659 isopropylmalate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034659 The directed movement of isopropylmalate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:140353 phosphatidic acid 40:6 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_140353 GO:0010689 negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to chemical stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010689 Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a chemical stimulus. CHEBI:140354 phosphatidic acid 38:4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_140354 GO:0009693 ethylene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009693 MetaCyc:ETHYL-PWY ethylene biosynthesis from L-methionine|ethylene biosynthetic process from L-methionine|ethene biosynthetic process|ethene biosynthesis|ethylene anabolism|ethene biosynthetic process from L-methionine|ethene biosynthesis from L-methionine|ethylene synthesis|ethylene formation|ethylene biosynthesis The chemical reactions and pathways resulting in the formation of ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator. GO:0010682 obsolete cinnamic acid biosynthetic process involved in flavonoid metabolism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010682 OBSOLETE. The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid, which is then utilized in the metabolism of flavonoids. GO:0010683 tricyclic triterpenoid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010683 tricyclic triterpenoid metabolism The chemical reactions and pathways involving tricyclic triterpenoid compounds, terpenoids with six isoprene units and 3 rings. GO:0009694 jasmonic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009694 jasmonic acid metabolism The chemical reactions and pathways involving jasmonic acid, a fatty acid derivative with the formula (1R-(1 alpha, 2 beta(Z)))-3-oxo-2-(2-pentenyl)cyclopentaneacetic acid. GO:0034650 cortisol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034650 cortisol metabolism The chemical reactions and pathways involving cortisol, the steroid hormone 11-beta-17,21-trihydroxypregn-4-ene-3,20-dione. Cortisol is synthesized from cholesterol in the adrenal gland and controls carbohydrate, fat and protein metabolism and has anti-inflammatory properties. GO:0034651 cortisol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034651 cortisol formation|cortisol biosynthesis|cortisol anabolism|cortisol synthesis The chemical reactions and pathways resulting in the formation of cortisol, the steroid hormone 11-beta-17,21-trihydroxypregn-4-ene-3,20-dione. Cortisol is synthesized from cholesterol in the adrenal gland and controls carbohydrate, fat and protein metabolism and has anti-inflammatory properties. GO:0009695 jasmonic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009695 MetaCyc:PWY-735 jasmonic acid biosynthesis|jasmonic acid anabolism|jasmonic acid synthesis|jasmonic acid formation The chemical reactions and pathways resulting in the formation of jasmonic acid, a fatty acid derivative. GO:0010680 obsolete cinnamic acid biosynthetic process involved in coumarin metabolism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010680 OBSOLETE. The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid, which is then utilized in the metabolism of coumarin. GO:0034652 extrachromosomal circular DNA localization involved in cell aging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034652 extrachromosomal circular DNA localization during cell ageing|extrachromosomal circular DNA localization during cell aging|extrachromosomal circular DNA localisation involved in cell aging A process in which extrachromosomal circular DNA molecules are transported to, or maintained in, a specific location in cells contributing to their aging. GO:0009696 salicylic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009696 salicylic acid metabolism The chemical reactions and pathways involving of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid. GO:0010681 obsolete cinnamic acid biosynthetic process involved in stilbene metabolism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010681 OBSOLETE. The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid, which is then utilized in the metabolism of stilbene. GO:0010686 tetracyclic triterpenoid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010686 tetracyclic triterpenoid biosynthesis The chemical reactions and pathways resulting in the formation of tetracyclic triterpenoid compounds, terpenoids with six isoprene units and 4 carbon rings. GO:0034653 retinoic acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034653 retinoic acid degradation|vitamin A1 acid catabolic process|retinoic acid breakdown|retinoic acid catabolism The chemical reactions and pathways resulting in the breakdown of retinoic acid, one of the three components that makes up vitamin A. GO:0009697 salicylic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009697 MetaCyc:PWY-981 salicylic acid biosynthesis|salicylic acid anabolism|salicylic acid synthesis|salicylic acid formation|salicylate biosynthetic process The chemical reactions and pathways resulting in the formation of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid. CHEBI:140359 UDP-monosaccharide(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140359 GO:0034654 nucleobase-containing compound biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034654 nucleobase, nucleoside, nucleotide and nucleic acid synthesis|nucleobase, nucleoside, nucleotide and nucleic acid anabolism|nucleobase, nucleoside, nucleotide and nucleic acid formation|nucleobase, nucleoside, nucleotide and nucleic acid biosynthesis The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids. GO:0010687 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010687 GO:0009698 phenylpropanoid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009698 MetaCyc:PWY1F-467 phenylpropanoid metabolism The chemical reactions and pathways involving aromatic derivatives of trans-cinnamic acid. GO:0009699 phenylpropanoid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009699 phenylpropanoid anabolism|phenylpropanoid synthesis|phenylpropanoid formation|phenylpropanoid biosynthesis The chemical reactions and pathways resulting in the formation of aromatic derivatives of trans-cinnamic acid. GO:0010684 tricyclic triterpenoid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010684 tricyclic triterpenoid catabolism The chemical reactions and pathways resulting in the breakdown of tricyclic triterpenoid compounds, terpenoids with six isoprene units and 3 rings. GO:0019018 obsolete bipartite viral genome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019018 OBSOLETE. A segmented viral genome consisting of two sub-genomic nucleic acids but each nucleic acid is packaged into a different virion. GO:0034655 nucleobase-containing compound catabolic process biolink:BiologicalProcess go-plus goslim_generic|goslim_chembl http://purl.obolibrary.org/obo/GO_0034655 nucleobase, nucleoside, nucleotide and nucleic acid catabolic process|nucleobase, nucleoside, nucleotide and nucleic acid breakdown|nucleobase, nucleoside, nucleotide and nucleic acid catabolism|nucleobase, nucleoside, nucleotide and nucleic acid degradation The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids. CHEBI:140357 N(4)-[alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-glycan]-L-asparagine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140357 GO:0034656 nucleobase-containing small molecule catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034656 nucleobase, nucleoside and nucleotide catabolism|nucleobase, nucleoside and nucleotide degradation|nucleobase, nucleoside and nucleotide breakdown The chemical reactions and pathways resulting in the breakdown of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide. CHEBI:140358 monosaccharide 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140358 GO:0010685 tetracyclic triterpenoid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010685 tetracyclic triterpenoid metabolism The chemical reactions and pathways involving tetracyclic triterpenoid compounds, terpenoids with six isoprene units and 4 carbon rings. GO:0019019 obsolete tripartite viral genome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019019 OBSOLETE. A segmented viral genome consisting of three sub-genomic nucleic acids but each nucleic acid is packaged into a different virion. GO:0020016 ciliary pocket biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0020016 flagellar pocket|cilial pocket|cilium pocket Invagination of the plasma membrane from which a cilium (also called flagellum) protrudes. GO:0019016 obsolete non-segmented viral genome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019016 OBSOLETE. A viral genome that consists of one continuous nucleic acid molecule. GO:0019017 obsolete segmented viral genome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019017 OBSOLETE. A viral genome that is divided into two or more physically separate molecules of nucleic acid and packaged into a single virion. GO:0020017 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0020017 GO:0020018 ciliary pocket membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0020018 cilium pocket membrane|cilial pocket membrane|flagellar pocket membrane That part of the plasma membrane found in the ciliary pocket (also called flagellar pocket). GO:0019014 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019014 GO:0019015 obsolete viral genome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019015 OBSOLETE. The whole of the genetic information of a virus, contained as either DNA or RNA. GO:0019012 virion biolink:CellularComponent go-plus goslim_pir|goslim_metagenomics|goslim_chembl http://purl.obolibrary.org/obo/GO_0019012 Wikipedia:Virus complete virus particle The complete fully infectious extracellular virus particle. GO:0019013 viral nucleocapsid biolink:CellularComponent go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0019013 nucleocapsid|core The complete protein-nucleic acid complex that is the packaged form of the genome in a virus particle. GO:0019010 farnesoic acid O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019010 S-adenosyl-methionine:farnesoic acid O-methyltransferase activity Catalysis of the reaction: farnesoic acid + S-adenosyl-methionine = methyl farnesoate + S-adenosyl-L-homocysteine. GO:0019011 obsolete DNA replication accessory factor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019011 DNA replication accessory factor OBSOLETE. (Was not defined before being made obsolete). GO:0019030 icosahedral viral capsid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019030 quasispherical viral capsid The protein coat that surrounds the infective nucleic acid in some virus particles; the subunits are arranged to form an icosahedron, a solid with 20 faces and 12 vertices. Icosahedral capsids have 12 pentamers plus 10(T-1) hexamers, where T is the triangulation number. Tobacco satellite necrosis virus has such a capsid structure. GO:0019031 viral envelope biolink:CellularComponent go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0019031 Wikipedia:Viral_envelope viral outside membrane|viral glycoprotein The lipid bilayer of a virion that surrounds the protein capsid. May also contain glycoproteins. CHEBI:139371 aryl sulfate oxoanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139371 CHEBI:72896 cardiolipin 72:4(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72896 CHEBI:139372 3-methylnonanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139372 GO:0020002 host cell plasma membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0020002 The plasma membrane surrounding a host cell. CHEBI:72899 cardiolipin 72:7(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72899 GO:0020003 symbiont-containing vacuole biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0020003 pathogen-occupied vacuole|SCV|Salmonella-containing vacuole|parasitophorous vacuole|bacterium-containing vacuole Membrane-bounded vacuole within a host cell in which a symbiont organism resides. The vacuole membrane is derived from both the host and symbiont. GO:0020004 symbiont-containing vacuolar space biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0020004 symbiont-containing vacuole space|parasitophorous vacuolar space The space between a symbiont plasma membrane and the symbiont-containing vacuole membrane. GO:0034646 organelle-enclosing lipid monolayer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034646 A lipid monolayer that surrounds and encloses an organelle. CHEBI:140345 hydroxy polyunsaturated fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_140345 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034647 EC:1.14.11.67 histone demethylase activity (H3-K4-me3 specific) Catalysis of the removal of a methyl group from trimethylated lysine at position 4 of the histone H3 protein. GO:0010699 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010699 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034648 histone demethylase activity (H3-K4-me2 specific) Catalysis of the removal of a methyl group from dimethylated lysine at position 4 of the histone H3 protein. GO:0034649 histone demethylase activity (H3-monomethyl-K4 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034649 histone demethylase activity (H3-K4-me1 specific) Catalysis of the reaction: histone H3 N6-methyl-L-lysine (position 4) + O2 + FAD + H2O = histone H3 L-lysine (position 4) + H2O2 + formaldehyde + FADH2. This reaction is the removal of a methyl group from monomethylated lysine at position 4 of the histone H3 protein. GO:0010693 negative regulation of alkaline phosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010693 Any process that decreases the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum. GO:0010694 positive regulation of alkaline phosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010694 Any process that increases the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum. GO:0034640 establishment of mitochondrion localization by microtubule attachment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034640 mitochondrial migration by microtubule attachment|mitochondrial localization by microtubule attachment|mitochondrion migration by microtubule attachment|establishment of mitochondrion localisation by microtubule attachment The directed movement of a mitochondrion by attachment to a microtubule, followed by elongation of the microtubule by tubulin polymerization. GO:0010691 negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010691 Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a stimulus reflecting the presence, absence, or concentration of nutrients. GO:0034641 cellular nitrogen compound metabolic process biolink:BiologicalProcess go-plus goslim_chembl|goslim_generic http://purl.obolibrary.org/obo/GO_0034641 cellular nitrogen compound metabolism The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells. GO:0010692 regulation of alkaline phosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010692 Any process that modulates the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum. GO:0010697 negative regulation of mitotic spindle pole body separation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010697 negative regulation of SPB separation Any process that decreases the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane. GO:0034642 mitochondrion migration along actin filament biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034642 mitochondrial migration along actin filament|mitochondrial migration, actin-mediated|mitochondrial migration along microfilament|mitochondrion migration along microfilament|mitochondrion transport along actin filament The directed movement of a mitochondrion along a microfilament, mediated by motor proteins. GO:0010698 acetyltransferase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010698 acetyltransferase stimulator activity Binds to and increases the activity of an acetyltransferase, an enzyme which catalyzes the transfer of an acetyl group to an acceptor molecule. GO:0034643 establishment of mitochondrion localization, microtubule-mediated biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034643 microtubule-mediated mitochondrion localization|mitochondrial localization, microtubule-mediated|establishment of mitochondrion localisation, microtubule-mediated The directed movement of the mitochondrion to a specific location, by a process involving microtubules. GO:0019029 helical viral capsid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019029 The protein coat that surrounds the infective nucleic acid in some virus particles; the subunits are arranged to form a protein helix with the genetic material contained within. Tobacco mosaic virus has such a capsid structure. GO:0034644 cellular response to UV biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034644 cellular response to ultraviolet light stimulus|cellular response to ultraviolet radiation stimulus|cellular response to UV light stimulus|cellular response to UV radiation stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers. GO:0010695 regulation of mitotic spindle pole body separation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010695 regulation of SPB separation Any process that modulates the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane. GO:0010696 positive regulation of mitotic spindle pole body separation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010696 positive regulation of SPB separation Any process that increases the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane. GO:0034645 cellular macromolecule biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034645 cellular macromolecule anabolism|cellular biopolymer biosynthetic process|cellular macromolecule biosynthesis|cellular macromolecule synthesis|cellular macromolecule formation The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells. CHEBI:140347 substituted beta-amino acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140347 GO:0020005 symbiont-containing vacuole membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0020005 parasitophorous vacuolar membrane The lipid bilayer surrounding a symbiont-containing vacuole, derived from both the host and symbiont. GO:0019027 obsolete ambisense viral genome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019027 OBSOLETE. A RNA genome that contains coding regions that are either positive sense or negative sense on the same RNA molecule. GO:0020006 symbiont-containing vacuolar membrane network biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0020006 tubulovesicular network|symbiont-containing vacuole membrane network|parasitophorous vacuolar membrane network Tubular network of extensions from the symbiont-containing vacuole membrane that protrude into the host cytoplasm. GO:0019028 viral capsid biolink:CellularComponent go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0019028 Wikipedia:Capsid The protein coat that surrounds the infective nucleic acid in some virus particles. It comprises numerous regularly arranged subunits, or capsomeres. GO:0019025 obsolete positive sense viral genome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019025 OBSOLETE. A single stranded RNA genome with the same nucleotide polarity as mRNA. GO:0020007 apical complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0020007 A group of cytoskeletal structures and associated membrane-bounded organelles found at the anterior end of adult obligate intracellular protozoan parasites in the phylum Apicomplexa. The apical complex is involved in attachment to and penetration of the host cell, and in parasite proliferation. GO:0020008 rhoptry biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0020008 Wikipedia:Rhoptry paired organelles|toxoneme A large, club-shaped secretory organelle that forms part of the apical complex of an apicomplexan parasite, and consists of a bulbous body and a narrow electron-dense neck that extends through the conoid at the apical tip of the parasite. The rhoptry necks serve as ducts through which the contents of the rhoptries are secreted after attachment to the host has been completed and at the commencement of invasion. Rhoptry proteins function in the biogenesis and host organellar association of the parasitophorous vacuole. GO:0019026 obsolete negative sense viral genome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019026 OBSOLETE. A single stranded RNA genome with the opposite nucleotide polarity as mRNA. GO:0019023 obsolete dsRNA viral genome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019023 OBSOLETE. A viral genome composed of double stranded RNA. GO:0020009 microneme biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0020009 Wikipedia:Microneme sarconeme A small, elongated secretory organelle that forms part of the apical complex, located along the main axis of an apicomplexan parasite cell within the extreme apical region and at the periphery under the inner membrane complex. Of the specialized secretory compartments identified in apicomplexans, micronemes discharge their contents first, during initial contact of the parasite's apical pole with the host cell surface. Micronemal proteins function during parasite attachment and penetration into the target cell. CHEBI:139362 2-hydroxy-3-methylundecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139362 GO:0010690 negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010690 Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a disturbance in organismal or cellular homeostasis. GO:0019024 obsolete ssRNA viral genome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019024 OBSOLETE. A viral genome composed of single stranded RNA of either positive or negative sense. CHEBI:139363 2-hydroxy-3-methylnonanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139363 GO:0019021 obsolete DNA viral genome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019021 OBSOLETE. A viral genome composed of deoxyribonucleic acid. CHEBI:72892 cardiolipin 70:6(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72892 GO:0019022 obsolete RNA viral genome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019022 OBSOLETE. A viral genome composed of ribonucleic acid. This results in genome replication and expression of genetic information being inextricably linked. GO:0034635 glutathione transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034635 The directed movement of glutathione, the tripeptide glutamylcysteinylglycine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0010668 ectodermal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010668 The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an ectodermal cell. Differentiation includes the processes involved in commitment of a cell to a specific fate. GO:0034636 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0034636 GO:0010669 epithelial structure maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010669 A tissue homeostatic process required for the maintenance of epithelial structure. GO:0034637 cellular carbohydrate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034637 The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, carried out by individual cells. GO:0010666 positive regulation of cardiac muscle cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010666 positive regulation of cardiac muscle cell apoptosis Any process that increases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death. CHEBI:140331 4'-hydroxyflavanones biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140331 GO:0034638 phosphatidylcholine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034638 phosphatidylcholine breakdown|phosphatidylcholine catabolism|phosphatidylcholine degradation The chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. GO:0010667 negative regulation of cardiac muscle cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010667 down regulation of cardiac muscle cell apoptosis|downregulation of cardiac muscle cell apoptosis|down-regulation of cardiac muscle cell apoptosis|negative regulation of cardiac muscle cell apoptosis|inhibition of cardiac muscle cell apoptosis Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death. CHEBI:140332 4'-methoxyflavanones biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140332 GO:0034639 L-amino acid efflux transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034639 L-amino acid export transporter activity|L-amino acid efflux permease activity Enables the transfer of an L-amino acid from the inside of the cell to the outside of the cell across a membrane. CHEBI:140330 (13R)-13-dihydrocarminomycin(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140330 GO:0009680 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009680 GO:0009681 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009681 GO:0010660 regulation of muscle cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010660 regulation of muscle cell apoptosis Any process that modulates the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death. GO:0009671 nitrate:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009671 nitrate:hydrogen symporter activity|nitrate(chlorate):hydrogen symporter activity|nitrate(chlorate):proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nitrate(out) + H+(out) = nitrate(in) + H+(in). GO:0010661 positive regulation of muscle cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010661 positive regulation of muscle cell apoptosis Any process that increases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death. GO:0009672 auxin:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009672 auxin:hydrogen symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: auxin(out) + H+(out) = auxin(in) + H+(in). GO:0009673 low-affinity phosphate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009673 low affinity phosphate transmembrane transporter activity Enables the transfer of phosphate from one side of a membrane to the other. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations. GO:0034630 RITS complex localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034630 establishment and maintenance of RITS complex localization|RITS complex localisation Any process in which a RITS complex is transported to, or maintained in, a specific location. GO:0009674 potassium:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009674 high affinity potassium transporter Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + Na+(out) = K+(in) + Na+(in). GO:0009675 high-affinity sulfate:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009675 high affinity sulfate:hydrogen symporter activity|high affinity sulfate:proton symporter activity|high affinity sulphate:hydrogen symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + H+(out) = sulfate(in) + H+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. GO:0010664 negative regulation of striated muscle cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010664 down-regulation of striated muscle cell apoptosis|negative regulation of striated muscle cell apoptosis|downregulation of striated muscle cell apoptosis|down regulation of striated muscle cell apoptosis|inhibition of striated muscle cell apoptosis Any process that decreases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death. GO:0034631 microtubule anchoring at spindle pole body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034631 microtubule anchoring at SPB|attachment of spindle microtubules to spindle pole body|attachment of spindle microtubules to SPB Any process in which a microtubule is maintained in a specific location in a cell by attachment to a spindle pole body. Microtubules attach to spindle pole bodies at the minus end. CHEBI:139337 (4Z,8Z)-4,8-dimethyl-12-oxotrideca-4,8-dienal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139337 GO:0009676 low-affinity sulfate:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009676 low affinity sulphate:hydrogen symporter activity|low affinity sulfate:hydrogen symporter activity|low affinity sulfate:proton symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + H+(out) = sulfate(in) + H+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations. GO:0034632 retinol transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034632 Reactome:R-HSA-1467466|Reactome:R-HSA-2466749|Reactome:R-HSA-2466802 vitamin A1 transporter activity|retinol transporter activity Enables the transfer of retinol from one side of a membrane to the other. Retinol is vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A. CHEBI:139338 EC 1.14.17.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen and with reduced ascorbate as one donor, and incorporation of one atom of oxygen) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139338 GO:0010665 regulation of cardiac muscle cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010665 regulation of cardiac muscle cell apoptosis Any process that modulates the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death. CHEBI:139339 EC 1.14.17.1 (dopamine beta-monooxygenase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139339 GO:0034633 retinol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034633 vitamin A1 transport The directed movement of retinol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Retinol is vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A. GO:0010662 regulation of striated muscle cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010662 regulation of striated muscle cell apoptosis Any process that modulates the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death. GO:0009677 double fertilization forming two zygotes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009677 Rudimentary double fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the ventral canal cell nucleus to form a second zygote, which soon degenerates. An example of this process is found in the Gnetophytes, such as Welwitschia mirabilis. CHEBI:140335 glucuronoxylan D-glucuronate polyanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140335 GO:0009678 pyrophosphate hydrolysis-driven proton transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009678 TC:3.A.10|MetaCyc:TRANS-RXN-370|RHEA:13973|EC:7.1.3.1 proton-pumping diphosphatase|proton-pumping pyrophosphatase|proton-translocating pyrophosphatase activity|PP(i) hydrolysis-driven proton transmembrane transporter activity|H(+)-exporting diphosphatase|hydrogen-translocating pyrophosphatase activity|diphosphate hydrolysis-driven proton transmembrane transporter activity Enables the transmembrane transport of one proton (H+), driven by the hydrolysis of pyrophosphate, and generating a proton motive force. GO:0034634 glutathione transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034634 Enables the transfer of glutathione, the tripeptide glutamylcysteinylglycine, from one side of a membrane to the other. GO:0010663 positive regulation of striated muscle cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010663 positive regulation of striated muscle cell apoptosis Any process that increases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death. CHEBI:140336 glucuronoxylan 4-O-methyl-D-glucuronate polyanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140336 GO:0009679 hexose:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009679 hexose:hydrogen symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexose(out) + H+(out) = hexose(in) + H+(in). CHEBI:139335 6-chloro-L-tryptophan zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139335 CHEBI:139336 6,7-dichloro-L-tryptophan zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139336 CHEBI:139332 5-chloro-L-tryptophan zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139332 GO:0034624 obsolete DNA recombinase assembly involved in gene conversion at mating-type locus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034624 OBSOLETE. The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) into higher order oligomers on single-stranded DNA, involved in the conversion of the mating-type locus from one allele to another. GO:0010679 obsolete cinnamic acid biosynthetic process involved in salicylic acid metabolism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010679 OBSOLETE. The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid, which is then utilized in the metabolism of salicylic acid. GO:0034625 fatty acid elongation, monounsaturated fatty acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034625 Elongation of a fatty acid chain into which one C-C double bond has been introduced. GO:0034626 fatty acid elongation, polyunsaturated fatty acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034626 Elongation of a fatty acid chain into which two or more C-C double bonds have been introduced. GO:0010677 negative regulation of cellular carbohydrate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010677 Any process that decreases the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells. GO:0034627 'de novo' NAD biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034627 de novo NAD biosynthetic process The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan or aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH. GO:0010678 negative regulation of cellular carbohydrate metabolic process by negative regulation of transcription, DNA-templated biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010678 negative regulation of cellular carbohydrate metabolic process by transcriptional repression|negative regulation of cellular carbohydrate metabolic process by repression of transcription|negative regulation of cellular carbohydrate metabolic process by negative regulation of transcription, DNA-dependent Any cellular process that decreases the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates carried out by repression of transcription. GO:0034628 'de novo' NAD biosynthetic process from aspartate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034628 de novo NAD biosynthetic process from aspartate The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH. GO:0034629 cellular protein-containing complex localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034629 cellular protein complex localisation|cellular protein complex localization|establishment and maintenance of cellular protein complex localization A protein complex localization process that takes place at the cellular level; as a result, a protein complex is transported to, or maintained in, a specific location within a cell. GO:0009690 cytokinin metabolic process biolink:BiologicalProcess go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0009690 cytokinin metabolism The chemical reactions and pathways involving cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators. GO:0009691 cytokinin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009691 cytokinin synthesis|cytokinin formation|cytokinin biosynthesis|cytokinin anabolism The chemical reactions and pathways resulting in the formation of cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators. GO:0009692 ethylene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009692 ethylene metabolism|ethene metabolic process|ethene metabolism The chemical reactions and pathways involving ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator. CHEBI:57297 ent-kaur-16-en-19-oate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57297 GO:0010671 obsolete negative regulation of oxygen and reactive oxygen species metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010671 negative regulation of oxygen and reactive oxygen species metabolic process OBSOLETE. Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving dioxygen (O2), or any of the reactive oxygen species, e.g. superoxide anions (O2-), hydrogen peroxide (H2O2), and hydroxyl radicals (-OH). GO:0009682 induced systemic resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009682 A response to non-pathogenic bacteria that confers broad spectrum systemic resistance to disease that does not depend upon salicylic acid signaling. GO:0009683 indoleacetic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009683 IAA metabolic process|indoleacetic acid metabolism|indole acetic acid metabolic process|indole acetic acid metabolism The chemical reactions and pathways involving indole-3-acetic acid, a compound which functions as a growth regulator in plants. GO:0010672 regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010672 regulation of meiosis by regulation of transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter, meiotic Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle. CHEBI:57298 ent-7alpha-hydroxykaur-16-en-19-oate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57298 GO:0009684 indoleacetic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009684 indole-3-acetate biosynthesis|indole-3-acetate biosynthetic process|IAA biosynthetic process|indoleacetic acid biosynthesis|indoleacetic acid anabolism|indole-acetic acid biosynthesis|indoleacetic acid synthesis|indoleacetic acid formation|indole-acetic acid biosynthetic process|indole acetic acid biosynthetic process|indole acetic acid biosynthesis The chemical reactions and pathways resulting in the formation of indole-3-acetic acid, a compound which functions as a growth regulator in plants. CHEBI:140328 alpha-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140328 CHEBI:57295 (-)-ephedrinium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57295 GO:0009685 gibberellin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009685 gibberellin metabolism|gibberellic acid metabolism|gibberellic acid metabolic process The chemical reactions and pathways involving gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators. CHEBI:57296 (-)-ureidoglycolate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57296 CHEBI:140329 13-deoxycarminomycin(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140329 GO:0010670 obsolete positive regulation of oxygen and reactive oxygen species metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010670 positive regulation of oxygen and reactive oxygen species metabolic process OBSOLETE. Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving dioxygen (O2), or any of the reactive oxygen species, e.g. superoxide anions (O2-), hydrogen peroxide (H2O2), and hydroxyl radicals (-OH). GO:0009686 gibberellin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009686 MetaCyc:PWY-5036|MetaCyc:PWY-5035|MetaCyc:PWY-5052|MetaCyc:PWY-5070 gibberellic acid anabolism|gibberellic acid synthesis|gibberellic acid biosynthesis|gibberellic acid biosynthetic process|gibberellic acid formation|gibberellin biosynthesis The chemical reactions and pathways resulting in the formation of gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators. GO:0034620 cellular response to unfolded protein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034620 heat shock protein activity Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus. GO:0010675 regulation of cellular carbohydrate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010675 Any process that modulates the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells. GO:0019009 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019009 CHEBI:140326 tertiary carboxamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140326 CHEBI:57293 (+)-bornyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57293 GO:0009687 abscisic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009687 abscisic acid metabolism The chemical reactions and pathways involving abscisic acid, 5-(1-hydroxy-2,6,6,trimethyl-4-oxocyclohex-2-en-1-y1)-3-methylpenta-2,4-dienoic acid. CHEBI:140327 alpha-L-fucosyl-(1->2)-beta-D-galactoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140327 CHEBI:57294 (+)-dihydrokaempferol 7-oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_57294 GO:0034621 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0034621 GO:0010676 positive regulation of cellular carbohydrate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010676 Any process that increases the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells. GO:0009688 abscisic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009688 MetaCyc:PWY-695 abscisic acid biosynthesis|abscisic acid anabolism|abscisic acid synthesis|abscisic acid formation The chemical reactions and pathways resulting in the formation of abscisic acid, 5-(1-hydroxy-2,6,6,trimethyl-4-oxocyclohex-2-en-1-y1)-3-methylpenta-2,4-dienoic acid. GO:0010673 positive regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010673 up regulation of meiosis by positive regulation of transcription from RNA polymerase II promoter|activation of meiosis by positive regulation of transcription from RNA polymerase II promoter|stimulation of meiosis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of meiosis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter, meiotic|positive regulation of meiosis by positive regulation of transcription from RNA polymerase II promoter|upregulation of meiosis by positive regulation of transcription from RNA polymerase II promoter Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle. GO:0034622 cellular protein-containing complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034622 cellular macromolecule complex assembly|cellular protein complex assembly The aggregation, arrangement and bonding together of a set of components to form a protein complex, occurring at the level of an individual cell. OBA:VT0015108 neurite morphology trait biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_VT0015108 morphology of neuron projection The morphology of a neuron projection. CHEBI:140324 primary carboxamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140324 CHEBI:57291 3-oxopristanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57291 GO:0019007 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019007 GO:0019008 molybdopterin synthase complex biolink:CellularComponent go-plus goslim_metagenomics http://purl.obolibrary.org/obo/GO_0019008 molybdopterin converting factor complex A protein complex that possesses molybdopterin synthase activity. In E. coli, the complex is a heterotetramer consisting of two MoaD and two MoaE subunits. GO:0009689 induction of phytoalexin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009689 induction of phytoalexin anabolism|induction of phytoalexin synthesis|induction of phytoalexin formation|induction of phytoalexin biosynthesis The activation of the chemical reactions and pathways resulting in the formation of phytoalexins, low-molecular mass, lipophilic antimicrobial compounds that accumulate rapidly at sites of incompatible pathogen infection. GO:0010674 negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010674 up regulation of meiosis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter, meiotic|activation of meiosis by negative regulation of transcription from RNA polymerase II promoter|stimulation of meiosis by negative regulation of transcription from RNA polymerase II promoter|up-regulation of meiosis by negative regulation of transcription from RNA polymerase II promoter|positive regulation of meiosis by negative regulation of transcription from RNA polymerase II promoter|upregulation of meiosis by negative regulation of transcription from RNA polymerase II promoter Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle. CHEBI:140325 secondary carboxamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140325 CHEBI:57292 succinyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_57292 GO:0034623 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0034623 GO:0019005 SCF ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019005 Wikipedia:SCF_complex CDL1 complex|Skp1/Cul1/F-box protein complex|cullin-RING ligase 1|SCF complex substrate recognition subunit|SCF complex|CRL1 complex|Cul1-RING ubiquitin ligase complex A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1). GO:0019006 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019006 GO:0019003 GDP binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019003 Interacting selectively and non-covalently with GDP, guanosine 5'-diphosphate. CHEBI:139346 all-trans-4-hydroxyretinal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139346 GO:0019004 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019004 CHEBI:139340 1,3-dihydroimidazole-2-thiones biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139340 GO:0019001 guanyl nucleotide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019001 Reactome:R-HSA-156909 Interacting selectively and non-covalently with guanyl nucleotides, any compound consisting of guanosine esterified with (ortho)phosphate. GO:0019002 GMP binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019002 Interacting selectively and non-covalently with GMP, guanosine monophosphate. CHEBI:57299 ATP(3-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_57299 GO:0019000 obsolete endonuclease G activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019000 endonuclease G activity OBSOLETE. (Was not defined before being made obsolete). CHEBI:47804 dibenzoazepine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47804 CHEBI:47805 25-hydroxy-24-oxocalciol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47805 CHEBI:47806 oxocalciol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47806 CHEBI:23843 disaccharide phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23843 CHEBI:23849 diterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23849 UBERON:0014283 piriform cortex layer 3 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014283 piriform cortex layer 3|layer 3 of piriform cortex|layer 3 of piriform cortex Deepest of 3 cytoarchitecturally defined layers of the piriform cortex characterized by a moderately high density of pyramidal cells and large numbers of basal dendrites descending from pyramidal cells in layer 2. CHEBI:23812 dimethylmaleic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23812 CHEBI:23818 dimethylxanthine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23818 CHEBI:23816 dimethylsilanediol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_23816 CHEBI:23822 dinitrotoluene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23822 CHEBI:23825 dibenzodioxine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23825 CHEBI:23824 diol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23824 CHEBI:72800 sphinga-4E,8E-dienine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72800 CHEBI:72801 5-HEPE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72801 CHEBI:72802 18-HEPE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72802 CHEBI:1449 3-amino-2-oxopropyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_1449 CHEBI:72804 HOTrE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72804 CHEBI:72805 2-alkyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72805 CHEBI:1447 3-acylpyruvic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_1447 CHEBI:72810 2'-deoxynebularine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72810 CHEBI:72812 oxooctadecadienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72812 CHEBI:72813 exopolysaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72813 CHEBI:23809 dimethylbenzimidazole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23809 CHEBI:23806 dimethylaniline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23806 CHEBI:72823 glycerophosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72823 CHEBI:72824 1-(Z-alk-1-enyl)-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72824 CHEBI:1427 3-(3-hydroxyphenyl)propanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_1427 CHEBI:72826 1-tetradecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72826 CHEBI:72827 1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72827 CHEBI:72828 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72828 CHEBI:72829 1,2-dipalmitoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72829 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034594 Catalysis of the reaction: phosphatidylinositol trisphosphate + H2O = phosphatidylinositol bisphosphate + phosphate. GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034595 phosphoinositide 5-phosphatase activity|polyphosphoinositol lipid 5-phosphatase activity Catalysis of the removal of the 5-phosphate group of a phosphatidylinositol phosphate. GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034596 Reactome:R-HSA-1676133|Reactome:R-HSA-8849969|Reactome:R-HSA-1675988|Reactome:R-HSA-1676124 inositol 4-phosphatase|phosphoinositide 4-phosphatase activity|PtdIns4P-phosphatase activity|PI(4)P-phosphatase activity|PI4P-phosphatase activity Catalysis of the removal of the 4-phosphate group of a phosphatidylinositol phosphate. GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034597 Reactome:R-HSA-6810410|MetaCyc:3.1.3.66-RXN|EC:3.1.3.66 phosphatidyl-myo-inositol-4,5-bisphosphate 4-phosphohydrolase activity|inositol polyphosphate 4-phosphatase type II activity|1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 4-phosphohydrolase activity Catalysis of the reaction: 1-phosphatidyl-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate. GO:0034598 phosphothreonine lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034598 Catalysis of the removal of the phosphate group from phosphothreonine by cleavage of the C-OP bond with the concomitant abstraction of the alpha proton, generating a double bond-containing product. GO:0034599 cellular response to oxidative stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034599 adaptive response to oxidative stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. GO:0034590 L-hydroxyproline transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034590 Reactome:R-HSA-6784213 4-hydroxyproline transmembrane transporter activity Enables the transfer of L-hydroxyproline from one side of a membrane to the other. GO:0034591 rhoptry lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034591 The volume enclosed by the rhoptry membrane. GO:0034592 synaptic vesicle lumen biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0034592 The volume enclosed by the synaptic vesicle membrane. GO:0034593 phosphatidylinositol bisphosphate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034593 triphosphoinositide phosphomonoesterase activity|phosphatidylinositol-bisphosphatase activity|diphosphoinositide phosphatase activity|triphosphoinositide phosphatase activity|phosphatidyl-inositol-bisphosphate phosphatase activity Catalysis of the reaction: phosphatidylinositol bisphosphate + H2O = phosphatidylinositol phosphate + phosphate. CHEBI:72830 2-hexadecanoyl-1-tetradecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72830 CHEBI:72831 2-hexadecanoyl-1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72831 CHEBI:72832 1-[(9Z)-octadec-9-enoyl]-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72832 CHEBI:72833 1-hexadecanoyl-sn--glycero-3-phospho-D-myo-inositol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72833 CHEBI:72834 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-icosatetraenoyl)-sn-glycero-3-phospho-D-myo-inositol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72834 CHEBI:72835 1,2-dihexadecanoyl-sn-glycero-3-phospho-D-myo-inositol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72835 CHEBI:72836 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phospho-D-myo-inositol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72836 CHEBI:1438 3-(methylthio)propionic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_1438 CHEBI:72837 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-D-myo-inositol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72837 CHEBI:72838 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-D-myo-inositol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72838 CHEBI:72839 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72839 GO:0034583 21U-RNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034583 Interacting selectively and non-covalently with a 21U-RNA, a 21-nucleotide RNA characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome. GO:0034584 piRNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034584 Piwi-associated RNA binding Interacting selectively and non-covalently with a piRNA, a Piwi-associated RNA, a 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism. GO:0034585 21U-RNA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034585 21U-RNA metabolism The chemical reactions and pathways involving 21U-RNAs, a class of single-stranded RNA molecules of about 21 nucleotides in length characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome. GO:0034586 21U-RNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034586 21U-RNA degradation|21U-RNA breakdown|21U-RNA catabolism The chemical reactions and pathways resulting in the breakdown of 21U-RNAs, a class of single-stranded RNA molecules of about 21 nucleotides in length characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome. GO:0034587 piRNA metabolic process biolink:BiologicalProcess go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0034587 piRNA metabolism|Piwi-associated RNA metabolic process The chemical reactions and pathways involving piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism. GO:0034588 piRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034588 piRNA degradation|piRNA breakdown|Piwi-associated RNA catabolic process|piRNA catabolism The chemical reactions and pathways resulting in the breakdown of piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism. GO:0034589 hydroxyproline transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034589 L-hydroxyproline transport|4-hydroxyproline transport The directed movement of hydroxyproline into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0034580 4-methyloctanoyl-CoA dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034580 UM-BBD_reactionID:r0924|EC:1.3.99.- Catalysis of the reaction: 4-methyloctanoyl-CoA = 4-methyloct-2-enoyl-CoA + 2 H+ + 2 e-. GO:0034581 4-methyloct-2-enoyl-CoA hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034581 UM-BBD_reactionID:r0925 Catalysis of the reaction: 4-methyloct-2-enoyl-CoA + H2O = 3-hydroxy-4-methyloctanoyl-CoA. GO:0034582 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034582 UM-BBD_reactionID:r0926 Catalysis of the reaction: 3-hydroxy-4-methyloctanoyl-CoA = 4-methyl-3-oxooctanoyl-CoA + 2 H+ + 2 e-. CHEBI:47885 dinucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47885 CHEBI:47880 steroid ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47880 CHEBI:47881 3-oxo monocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47881 CHEBI:47882 cyclic polypyrrole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47882 CHEBI:33231 antitubercular agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33231 CHEBI:33232 application biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33232 CHEBI:33233 fundamental particle biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33233 CHEBI:33234 vitamin E biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33234 CHEBI:33235 tocotrienol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33235 CHEBI:33237 vitamin D4 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33237 CHEBI:33238 monoatomic entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33238 CHEBI:47877 hexose 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47877 CHEBI:47878 hexose phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47878 CHEBI:47879 3-hydroxymethylcephalosporin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47879 CHEBI:47870 (methylthio)acetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47870 CHEBI:47871 mercaptopropanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47871 CHEBI:33242 inorganic hydride biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33242 CHEBI:33245 organic fundamental parent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33245 CHEBI:33246 inorganic group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33246 CHEBI:33247 organic group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33247 CHEBI:33248 hydrocarbyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33248 CHEBI:33249 organyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33249 UBERON:0004895 alveolar smooth muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004895 Alveolar smooth muscle is a type of non-striated muscle, found within the walls of the alveolus CHEBI:33240 coordination entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33240 UBERON:0004893 interalveolar septum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004893 septum interalveolare|alveolar septum A the thin septum that separates adjacent pulmonary alveoli, containing connective tissue constituents of the respiratory tissue and the capillary network of the blood supply of the lung. UBERON:0004894 alveolar wall biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004894 alveolus wall|pulmonary interalveolar septum|wall of pulmonary alveolus|pulmonary alveolar wall A wall that contains the alveoli CHEBI:33241 oxoacid derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33241 CHEBI:23895 ecdysteroid ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23895 CHEBI:23899 icosanoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23899 CHEBI:47867 indicator biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47867 CHEBI:47868 photosensitizing agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47868 CHEBI:23897 ecdysteroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23897 UBERON:0004880 chordamesoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004880 presumptive notochord|chorda mesoderm|axial chorda mesoderm|dorsal mesoderm The central region of trunk mesoderm. This tissue forms the notochord CHEBI:1467 (2S)-2-isopropyl-3-oxosuccinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_1467 CHEBI:33216 bisphenol A biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33216 CHEBI:47869 thioglycolate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47869 UBERON:0004889 lobar bronchus vasculature biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004889 Vasculature that is composed of the tubule structures that carry blood or lymph in the lungs UBERON:0004884 lobar bronchus mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004884 mesenchyme of lobar bronchus The mass of tissue composed of mesenchymal cells in the lobar bronchus.. CHEBI:1461 3-butynoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_1461 UBERON:0004883 lung mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004883 pulmonary mesenchyme|lung-associated mesenchyme|mesenchyme of lung The mass of tissue made up of mesenchymal cells in the lung. UBERON:0004869 parietal organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004869 third eye|parietal eye A part of the epithalamus present in some animal species. The eye may be photoreceptive and is usually associated with the pineal gland, regulating circadian rhythmicity and hormone production for thermoregulation. The parietal eye is a part of the epithalamus, which can be divided into two major parts; the epiphysis (the pineal organ, or pineal gland if mostly endocrine) and the parietal organ (often called the parietal eye, or third eye if it is photoreceptive). It arises as an anterior evagination of the pineal organ or as a separate outgrowth of the roof of the diencephalon. In some species, it protrudes through the skull.[4] The parietal eye uses a different biochemical method of detecting light than rod cells or cone cells in a normal vertebrate eye[WP]. CHEBI:47857 ureas biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47857 CHEBI:33229 vitamin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33229 CHEBI:33221 corrin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33221 CHEBI:33224 chromane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33224 CHEBI:33227 (E)-cinnamyl alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33227 CHEBI:47858 1-piperideine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47858 UBERON:0004875 nephrogenic cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004875 chorda nephrogenica A portion of the urogenital ridge which is the source of much of the urinary system[WP]. UBERON:0004876 urogenital fold biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004876 urethral fold|urogenital ridge|urogenital fold One of of the pair of folds derived from the cloacal folds which give rise to a portion of the external genitalia; in male embryos they close over the urethral plate and fuse to form the spongy (penile) urethra and ventral aspect of the penis, not including the glans; failure of fusion of the urethral folds leads to hypospadias; in female embryos they fuse only anterior to the anus and form the labia minora[MP]. UBERON:0004873 splanchnopleure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004873 ventral splanchnic mesoderm A structure created during embryogenesis when the lateral mesoderm splits into two layers - the inner (or splanchnic) layer adheres to the endoderm, and with it forms the splanchnopleure[WP]. UBERON:0004874 somatopleure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004874 A structure created during embryogenesis when the lateral mesoderm splits into two layers - the outer (or somatic) layer becomes applied to the inner surface of the ectoderm, and with it forms the somatopleure.[WP]. UBERON:0004871 somatic layer of lateral plate mesoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004871 outer layer of lateral plate mesoderm|somatic mesoderm|parietal mesoderm Layer of lateral plate mesoderm that forms the future body wall - underlies the ectoderm[WP]. CHEBI:1472 3-chloro-cis,cis-muconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_1472 UBERON:0004872 splanchnic layer of lateral plate mesoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004872 inner layer of lateral plate mesoderm|visceral mesoderm|splanchnic mesoderm Layer of lateral plate mesoderm that forms the circulatory system and future gut wall - overlies endoderm[WP]. CHEBI:23872 dodecyl sulfate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_23872 CHEBI:47843 dithiane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47843 CHEBI:47844 1,2-dithiane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47844 CHEBI:23875 dolichol phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23875 CHEBI:47830 hydroxyarginine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47830 CHEBI:47833 methionine sulfoximine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47833 CHEBI:23888 drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23888 CHEBI:33203 (Z)-24-ethylidenelophenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33203 CHEBI:47836 oxo seco-steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47836 CHEBI:47820 (1S)-1-hydroxy-23-oxo-24,25,26,27-tetranorcalciol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47820 CHEBI:47821 N(5)-[(E)-amino(hydroxyimino)methyl]-L-ornithine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47821 CHEBI:47822 N(5)-[(Z)-amino(hydroxyimino)methyl]-L-ornithine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47822 CHEBI:47823 N(omega)-hydroxyarginine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47823 CHEBI:23853 dithiol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23853 CHEBI:23858 behenate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_23858 CHEBI:47825 N(5)-[(E)-amino(hydroxyimino)methyl]ornithine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47825 CHEBI:47826 N(5)-[amino(hydroxyimino)methyl]ornithine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47826 CHEBI:47827 N(5)-[(hydroxyamino)(imino)methyl]ornithine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47827 CHEBI:47828 calcitroic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47828 CHEBI:23866 dodecanols biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23866 CHEBI:47811 penamcarboxylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47811 CHEBI:47812 (1S)-1,25-dihydroxy-24-oxocalciol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47812 CHEBI:47813 (1S)-1,23,25-trihydroxy-24-oxocalciol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47813 CHEBI:23869 dodecenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23869 CHEBI:23867 dodecenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23867 CHEBI:47818 (1S)-1,23-dihydroxy-24,25,26,27-tetranorcalciol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47818 CHEBI:47819 N(5)-[amino(hydroxyimino)methyl]-L-ornithine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47819 UBERON:0004938 submucosa of biliary tree biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004938 biliary tree submucosa|biliary tract submucosa|submucosa of biliary tract A submucosa that is part of a biliary tree [Automatically generated definition]. UBERON:0004939 submucosa of common bile duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004939 common bile ductal submucosa|ductus choledochus (biliaris) submucosa|common bile duct submucosa|submucosa of ductus choledochus (biliaris) A submucosa that is part of a common bile duct [Automatically generated definition]. UBERON:0004936 submucosa of pyloric antrum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004936 stomach pyloric antrum submucosa|antrum of stomach submucosa|submucosa of antrum of stomach|submucosa of stomach pyloric antrum|pyloric antrum submucosa A submucosa that is part of a pyloric antrum [Automatically generated definition]. UBERON:0004937 submucosa of pylorus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004937 submucosa of stomach pyloric region|stomach pyloric region submucosa|pyloric part of stomach submucosa|pylorus submucosa|pyloric submucosa|submucosa of pyloric part of stomach A submucosa that is part of a pylorus [Automatically generated definition]. UBERON:0004934 submucosa of body of stomach biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004934 stomach body submucosa|submucosa of gastric body|gastric body submucosa|corpus gastricum (ventriculare) submucosa|submucosa of stomach body|submucosa of corpus gastricum (ventriculare)|body of stomach submucosa A submucosa that is part of a body of stomach [Automatically generated definition]. GO:0010767 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010767 Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a UV damage stimulus. CHEBI:140432 [(9Z)-hexadecenoyl]-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140432 GO:0034734 transcription factor TFIIIC1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034734 A transcription factor complex that forms part of the TFIIIC complex, observed in human. The complex is poorly characterized, but contains the 250-kDa form of HsBdp1, and is thought to include nuclear factor 1 (NF1). It stimulates binding by human TFIIIC2 and is required for transcription activity. GO:0010768 negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010768 Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a UV damage stimulus. CHEBI:140433 GDP-6-deoxy-alpha-D-altrose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140433 GO:0034735 transcription factor TFIIIC2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034735 A transcription factor complex that forms part of the TFIIIC complex, observed in human; composed of five subunits (GTF3C1/hTFIIIC220/TFIIICalpha, GTF3C2/hTFIIIC110/TFIIICbeta, GTF3C3/hTFIIIC102/TFIIICgamma, GTF3C4/hTFIIIC90/TFIIICdelta and GTF3C5/hTFIIIC63/TFIIICepsilon in human) that together recognize the type 2 RNA polymerase III promoter. GO:0034736 cholesterol O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034736 MetaCyc:STEROL-O-ACYLTRANSFERASE-RXN|EC:2.3.1.26|RHEA:17729|KEGG_REACTION:R01461|Reactome:R-HSA-8876696 cholesterol ester synthetase activity|cholesterol acyltransferase activity|cholesteryl ester synthetase activity|ACAT activity|acyl coenzyme A-cholesterol-O-acyltransferase activity|acyl-CoA:cholesterol acyltransferase activity|acylcoenzyme A:cholesterol O-acyltransferase activity|acyl-CoA:cholesterol O-acyltransferase activity Catalysis of the reaction: acyl-CoA + cholesterol = a cholesterol ester + CoA. GO:0010765 positive regulation of sodium ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010765 Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0010766 negative regulation of sodium ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010766 Any process that decreases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0034737 ergosterol O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034737 Catalysis of the reaction: acyl-CoA + ergosterol = CoA + ergosterol ester. GO:0034738 lanosterol O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034738 Catalysis of the reaction: acyl-CoA + lanosterol = CoA + lanosterol ester. GO:0034739 histone deacetylase activity (H4-K16 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034739 Catalysis of the reaction: histone H4 N6-acetyl-L-lysine (position 16) + H2O = histone H4 L-lysine (position 16) + acetate. This reaction represents the removal of an acetyl group from lysine at position 16 of the histone H4 protein. GO:0010769 regulation of cell morphogenesis involved in differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010769 Any process that modulates the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. GO:0009780 photosynthetic NADP+ reduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009780 An NADPH regeneration process that contributes to the light reactions of photosynthesis. The light reactions of photosynthesis use energy from photons to generate high-energy electrons. These electrons are used directly to reduce NADP+ to NADPH. NADPH is a relatively stable molecule and can pass on its hydrogen atom to other molecules in chemical reactions. CHEBI:33198 D-gluconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33198 GO:0009770 primary charge separation in photosystem I biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009770 Energized reaction-center P700 chlorophylls on photosystem I donate an electron to a loosely bound Quinone acceptor molecule X, on the stromal surface of the thylakoid membrane. The result is charge separation; a negative charge on the stromal side of the thylakoid membrane and a positive charge on the luminal side. GO:0009771 primary charge separation in photosystem II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009771 Energized reaction-center P680 chlorophylls on photosystem II donate an electron to a loosely bound acceptor molecule, the quinone Q, on the stromal surface of the thylakoid membrane. The result is charge separation; a negative charge on the stromal side of the thylakoid membrane and a positive charge on the luminal side. GO:0010760 negative regulation of macrophage chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010760 Any process that decreases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus. CHEBI:33199 propynoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33199 GO:0009772 photosynthetic electron transport in photosystem II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009772 A photosynthetic electron transport chain in which electrons move from the primary electron acceptor (Quinone, Q) through a chain of electron transport molecules in the thylakoid membrane until they reach the ultimate electron acceptor of Photosystem II, which is plastocyanin (PC). The electron is then passed to the P700 chlorophyll a molecules of the reaction centre of photosystem I. CHEBI:140439 3-geranyl-3-[(Z)-2-isocyanovinyl]-3H-indole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140439 GO:0009773 photosynthetic electron transport in photosystem I biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009773 A photosynthetic electron transport chain in which electrons move from the primary electron acceptor (Quinone, X) through a chain of electron transport molecules in the thylakoid membrane until they reach ferredoxin which passes the electron to the ultimate electron acceptor; NADP. GO:0010763 positive regulation of fibroblast migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010763 positive regulation of fibroblast cell migration Any process that increases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium. GO:0034730 SmD-containing SMN-Sm protein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034730 SMN-containing protein complex An SMN-Sm protein complex formed by the association of the methylated Sm proteins B/B', D1, D2, D3, E, F, and G with the SMN complex. GO:0009774 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009774 GO:0034731 Lsm-containing SMN-Sm protein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034731 SMN-containing protein complex An SMN-Sm protein complex formed by the association of the methylated Sm proteins B/B', D3, E, F, and G, and Lsm10 and Lsm11, with the SMN complex. This complex forms Sm cores on U7 snRNA. GO:0010764 negative regulation of fibroblast migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010764 negative regulation of fibroblast cell migration Any process that decreases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium. GO:0009775 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009775 GO:0010761 fibroblast migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010761 fibroblast cell migration Cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium. A fibroblast is a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. GO:0009776 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009776 CHEBI:140434 3-[(Z)-2-isocyanovinyl]indole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140434 GO:0034732 transcription factor TFIIIB-alpha complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034732 A transcription factor TFIIIB-beta complex that contains the TATA-binding protein (TBP), B'' and a specialized homolog of the conserved subunit BRF referred to as BRFU or TFIIIB50, which found in human but not conserved in yeast; the complex is involved in the regulation of transcription from type 3 (upstream) RNA polymerase III promoters. GO:0034733 transcription factor TFIIIB-beta complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034733 A transcription factor TFIIIB-beta complex that contains the TATA-binding protein (TBP), B'' and BRF, and is involved in the regulation of transcription from type 2 RNA polymerase III promoters. GO:0009777 photosynthetic phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009777 photosynthetic ATP synthesis Any metabolic process in which photosynthetic organisms use light energy to convert ADP to ATP without the concomitant reduction of dioxygen (O2) to water that occurs in phosphorylation. GO:0010762 regulation of fibroblast migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010762 regulation of fibroblast cell migration Any process that modulates the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium. GO:0009778 cyclic photosynthetic phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009778 A photosynthetic phosphorylation process in which ATP synthesis is driven by a proton gradient generated across the thylakoid membrane. Involves only photosystem I. UBERON:0004943 submucosa of urinary bladder biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004943 tela submucosa vesicae|bladder submucosa|tela submucosa vesicae urinariae|submucous layer of urinary bladder|submucosa of bladder|tela submucosa (vesica urinaria)|urinary bladder submucosa The submucous layer of the wall of the urinary bladder. CHEBI:33190 3-oxopropanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33190 GO:0009779 noncyclic photosynthetic phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009779 A photosynthetic phosphorylation process in which ATP synthesis is linked to the transport of electrons from water to NADP+ with the production of NADPH and dioxygen (O2). Involves photosystem I and photosystem II. UBERON:0004941 submucosa of right hepatic duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004941 right hepatic duct submucosa|right hepatic ductal submucosa A submucosa that is part of a right hepatic duct [Automatically generated definition]. OBO:GOCHE_26645 substance with semiochemical role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_26645 UBERON:0004942 submucosa of left hepatic duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004942 left hepatic ductal submucosa|left hepatic duct submucosa A submucosa that is part of a left hepatic duct [Automatically generated definition]. UBERON:0004940 submucosa of common hepatic duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004940 common hepatic ductal submucosa|hepatic duct submucosa|common hepatic duct submucosa|submucosa of hepatic duct A submucosa that is part of a common hepatic duct [Automatically generated definition]. CHEBI:33196 (3R)-3-hydroxy-L-aspartate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33196 CHEBI:33197 (R)-10-hydroxyoctadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33197 UBERON:0004929 submucosa of ascending colon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004929 ascending colon submucosa A submucosa that is part of an ascending colon [Automatically generated definition]. UBERON:0004927 submucosa of cecum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004927 submucosa of intestinum crassum caecum|submucosa of caecum|cecum submucosa|intestinum crassum caecum submucosa|caecum submucosa A submucosa that is part of a cecum [Automatically generated definition]. UBERON:0004926 submucosa of cystic duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004926 cystic ductal submucosa|cystic duct submucosa A submucosa that is part of a cystic duct [Automatically generated definition]. UBERON:0004923 organ component layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004923 A part of a wall of an organ that forms a layer. UBERON:0004924 submucosa of pharynx biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004924 tela submucosa pharyngea|pharyngeal submucosa|submucous layer of pharynx|submucous coat of pharynx|pharyngobasilar fascia|pharynx submucosa|tela submucosa pharyngis The tissue underlying the tunica mucosa of the pharynx. GO:0034723 DNA replication-dependent nucleosome organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034723 DNA replication-dependent nucleosome organisation The formation or destruction of chromatin structures on newly replicated DNA, coupled to strand elongation. GO:0010778 meiotic DNA repair synthesis involved in reciprocal meiotic recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010778 The synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate. GO:0034724 DNA replication-independent nucleosome organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034724 DNA replication-independent nucleosome organisation The formation or destruction of chromatin structures, occurring outside the context of DNA replication. GO:0010779 meiotic DNA repair synthesis involved in meiotic gene conversion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010779 The synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another. PR:000008476 orexin biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000008476 hypocretin|PPORX|OX|PPOX|HCRT|Hcrt A protein that is a translation product of the human HCRT gene or a 1:1 ortholog thereof. GO:0010776 meiotic mismatch repair involved in meiotic gene conversion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010776 A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another. GO:0034725 DNA replication-dependent nucleosome disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034725 The controlled breakdown of nucleosomes on newly replicated DNA, coupled to strand elongation. GO:0034726 DNA replication-independent nucleosome disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034726 The controlled breakdown of nucleosomes outside the context of DNA replication. GO:0010777 meiotic mismatch repair involved in reciprocal meiotic recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010777 A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate. GO:0034727 piecemeal microautophagy of the nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034727 PMN Degradation of a cell nucleus by lysosomal microautophagy. GO:0034728 nucleosome organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034728 nucleosome organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of one or more nucleosomes. GO:0034729 histone H3-K79 methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034729 histone H3 K79 methylation|histone H3K79me|histone lysine H3 K79 methylation The modification of histone H3 by addition of a methyl group to lysine at position 79 of the histone. GO:0009790 embryo development biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate|goslim_plant|goslim_generic|goslim_chembl http://purl.obolibrary.org/obo/GO_0009790 Wikipedia:Embryogenesis embryogenesis and morphogenesis|embryonal development|embryogenesis The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant. GO:0009791 post-embryonic development biolink:BiologicalProcess go-plus goslim_plant http://purl.obolibrary.org/obo/GO_0009791 The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development. GO:0009781 obsolete photosynthetic water oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009781 photosynthetic water oxidation OBSOLETE. Processes by which a molecule of water is oxidized during photosynthesis. P680+, the photochemically oxidized reaction-center chlorophyll of PSII, is a strong biological oxidant. The reduction potential of P680+ is more positive than that of water, and thus it can oxidize water to give O2 and H+ ions. The oxygen escapes as a gas while the H+ ions remain in solution inside the thylakoid vesicle. GO:0010770 positive regulation of cell morphogenesis involved in differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010770 Any process that increases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. GO:0009782 photosystem I antenna complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009782 The antenna complex of photosystem I. A photosystem has two closely linked components, an antenna containing light-absorbing pigments and a reaction center. Each antenna contains one or more light-harvesting complexes (LHCs). GO:0010771 negative regulation of cell morphogenesis involved in differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010771 Any process that decreases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. GO:0009783 photosystem II antenna complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009783 The antenna complex of photosystem II. A photosystem has two closely linked components, an antenna containing light-absorbing pigments and a reaction center. Each antenna contains one or more light-harvesting complexes (LHCs). GO:0009784 transmembrane receptor histidine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009784 Combining with a signal and transmitting the signal from one side of a membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-histidine = ADP + a protein-L-histidine phosphate. GO:0019108 aryl-aldehyde dehydrogenase (NAD) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019108 MetaCyc:ARYL-ALDEHYDE-DEHYDROGENASE-RXN|RHEA:11804|UM-BBD_reactionID:r0394|EC:1.2.1.29 aryl-aldehyde:NAD+ oxidoreductase activity Catalysis of the reaction: an aromatic aldehyde + NAD+ + H2O = an aromatic acid + NADH + H+. GO:0010774 meiotic strand invasion involved in reciprocal meiotic recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010774 The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate. GO:0009785 blue light signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009785 blue light signalling pathway The series of molecular signals initiated upon sensing of blue light by photoreceptor molecule, at a wavelength between 400nm and 470nm. CHEBI:140426 2,4,6-trichlorophenolate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140426 GO:0034720 histone H3-K4 demethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034720 H3K4 demethylation (me1 me2 and me3) The modification of histone H3 by the removal of a methyl group from lysine at position 4 of the histone. GO:0010775 meiotic strand invasion involved in meiotic gene conversion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010775 The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate resulting in meiotic recombination. GO:0009786 regulation of asymmetric cell division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009786 Any process that modulates the frequency, rate or extent of asymmetric cell division. GO:0019109 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019109 GO:0009787 regulation of abscisic acid-activated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009787 regulation of abscisic acid mediated signalling|regulation of abscisic acid mediated signaling pathway Any process that modulates the frequency, rate or extent of abscisic acid (ABA) signaling. GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034721 H3K4 demethylation (me3)|histone H3-K4 tridemethylation The modification of histone H3 by the removal of a methyl group from a trimetylated lysine at position 4 of the histone. GO:0019106 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019106 GO:0010772 meiotic DNA recombinase assembly involved in reciprocal meiotic recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010772 The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate. GO:0009788 negative regulation of abscisic acid-activated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009788 negative regulation of abscisic acid mediated signaling pathway|down-regulation of abscisic acid mediated signaling|negative regulation of abscisic acid mediated signalling|downregulation of abscisic acid mediated signaling|down regulation of abscisic acid mediated signaling|inhibition of abscisic acid mediated signaling Any process that stops, prevents, or reduces the frequency, rate or extent of abscisic acid (ABA) signaling. GO:0034722 gamma-glutamyl-peptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034722 RHEA:56784|EC:3.4.19.9|MetaCyc:3.4.19.9-RXN gamma-glutamyl hydrolase activity Catalysis of the cleavage of a gamma-linked glutamate bond. GO:0019107 myristoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019107 Reactome:R-HSA-162914|Reactome:R-HSA-141367 Catalysis of the transfer of a myristoyl (CH3-[CH2]12-CO-) group to an acceptor molecule. GO:0010773 meiotic DNA recombinase assembly involved in meiotic gene conversion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010773 The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another. GO:0019104 DNA N-glycosylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019104 Reactome:R-HSA-110251|Reactome:R-HSA-9629483|Reactome:R-HSA-110248|Reactome:R-HSA-5649673|Reactome:R-HSA-9629497|Reactome:R-HSA-5649658|Reactome:R-HSA-9635996|Reactome:R-HSA-9636008|Reactome:R-HSA-9629470|Reactome:R-HSA-9629149|Reactome:R-HSA-110219|EC:3.2.2.-|Reactome:R-HSA-110246|Reactome:R-HSA-110231|Reactome:R-HSA-9629499|Reactome:R-HSA-5220959|Reactome:R-HSA-9629492|Reactome:R-HSA-110234|Reactome:R-HSA-9629216|Reactome:R-HSA-5649664|Reactome:R-HSA-110218|Reactome:R-HSA-5221061|Reactome:R-HSA-5649681|Reactome:R-HSA-110250|Reactome:R-HSA-110232 DNA glycosylase activity|endonuclease VIII activity Catalysis of the removal of damaged bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site. GO:0009789 positive regulation of abscisic acid-activated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009789 positive regulation of abscisic acid mediated signaling pathway|positive regulation of abscisic acid mediated signalling|up regulation of abscisic acid mediated signaling|upregulation of abscisic acid mediated signaling|stimulation of abscisic acid mediated signaling|activation of abscisic acid mediated signaling|up-regulation of abscisic acid mediated signaling Any process that activates or increases the frequency, rate or extent of abscisic acid (ABA) signaling. UBERON:0004932 submucosa of sigmoid colon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004932 sigmoid colon submucosa A submucosa that is part of a sigmoid colon [Automatically generated definition]. GO:0019105 N-palmitoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019105 Catalysis of the transfer of a palmitoyl group to a nitrogen atom on the acceptor molecule. GO:0019102 male somatic sex determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019102 The determination of sex and sexual phenotypes in a male organism's soma. UBERON:0004930 submucosa of transverse colon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004930 transverse colon submucosa A submucosa that is part of a transverse colon [Automatically generated definition]. UBERON:0004931 submucosa of descending colon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004931 descending colon submucosa A submucosa that is part of a descending colon [Automatically generated definition]. GO:0019103 pyrimidine nucleotide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019103 Interacting selectively and non-covalently with pyrimidine nucleotide, any compound consisting of a pyrimidine nucleoside esterified with (ortho)phosphate. CHEBI:139446 Man-1-2-Ins-1-P-Cer(d18:0) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139446 GO:0019100 male germ-line sex determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019100 The determination of sex and sexual phenotype in a male organism's germ line. GO:0019101 female somatic sex determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019101 The determination of sex and sexual phenotypes in a female organism's soma. UBERON:0004916 anal sphincter biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004916 sphincter analia|anal region sphincter A sphincter muscle that is part of a anal region. UBERON:0004917 urethral sphincter biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004917 urethral sphincter muscle|sphincter muscle of urethra|sphincter of urethra|sphincter urethrae A sphincter muscle surrounding the urethra. UBERON:0004914 duodenal papilla biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004914 papilla duodenalis|papilla duodeni|papilla of duodenum One of the two small elevations on the mucosa of the duodenum, the major at the entrance of the conjoined pancreatic and common bile ducts and the minor at the entrance of the accessory pancreatic duct. UBERON:0004915 sphincter of hepatopancreatic ampulla biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004915 musculus sphincter ampullae|hepatopancreatic ampullary sphincter|sphincter of ampulla of vater|Oddi's sphincter|sphincter of Oddi|musculus sphincter ampullae hepatopancreatica muscular valve that controls the flow of digestive juices (bile and pancreatic juice) through the ampulla of Vater into the second part of the duodenum. Relaxed by the hormone Cholecystokinin (CCK) via vasoactive intestinal polypeptide (VIP).[WP]. UBERON:0004912 biliary bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004912 hepatic diverticulum UBERON:0004913 hepatopancreatic ampulla biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004913 ampulla of Vater|ampulla hepatopancreatica|papilla Vateri|Vater's ampulla|ampulla biliaropancreatica|biliaropancreatic ampulla|ampulla of bile duct|papilla duodeni major|ampulla Vaterii A dilation of the duodenal papilla that is the opening of the juncture of the common bile duct and the main pancreatic duct. GO:0010745 negative regulation of macrophage derived foam cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010745 Any process that decreases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions. GO:0034712 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0034712 GO:0034713 type I transforming growth factor beta receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034713 baboon receptor ligand|transforming growth factor beta receptor type I binding|TGF-beta type I binding|babo binding|baboon binding|sax binding|saxophone binding|tkv ligand|thickveins ligand|transforming growth factor beta ligand binding to type I receptor|thickveins binding|type I TGF-beta binding|saxophone ligand|tkv binding|sax ligand|baboon ligand|babo ligand Interacting selectively and non-covalently with a type I transforming growth factor beta receptor. GO:0010746 regulation of long-chain fatty acid import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010746 regulation of plasma membrane long-chain fatty acid transport Any process that modulates the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22. GO:0010743 regulation of macrophage derived foam cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010743 Any process that modulates the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions. GO:0034714 type III transforming growth factor beta receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034714 TGF-beta type III binding|transforming growth factor beta receptor type III binding|transforming growth factor beta ligand binding to type III receptor|betaglycan binding|type IIII TGF-beta binding Interacting selectively and non-covalently with a type III transforming growth factor beta receptor. GO:0034715 pICln-Sm protein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034715 6S pICln complex A protein complex that contains pICln (CLNS1A) and several Sm proteins, including SmD1, SmD2, SmE, SmF, and SmG. GO:0010744 positive regulation of macrophage derived foam cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010744 Any process that increases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions. GO:0010749 regulation of nitric oxide mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010749 regulation of nitric oxide-mediated signal transduction Any process that modulates the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is a series of molecular signals mediated by the detection of nitric oxide (NO). GO:0034716 Gemin3-Gemin4-Gemin5 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034716 A protein complex that contains Gemin3 (DDX20), Gemin4, and Gemin5, and can bind to snRNAs; may be an intermediate in SMN complex assembly. GO:0034717 Gemin6-Gemin7-unrip complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034717 A protein complex that contains Gemin6, Gemin7, and unrip (STRAP), and can bind to snRNAs; may play a role in snRNP assembly. GO:0034718 SMN-Gemin2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034718 A protein complex that contains the survival motor neuron (SMN) protein and Gemin2; may form the stable core of the larger SMN complex. GO:0010747 positive regulation of long-chain fatty acid import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010747 positive regulation of plasma membrane long-chain fatty acid transport Any process that increases the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22. GO:0034719 SMN-Sm protein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034719 SMN-containing protein complex A protein complex formed by the association of several methylated Sm proteins with the SMN complex; the latter contains the survival motor neuron (SMN) protein and at least eight additional integral components, including the Gemin2-8 and unrip proteins; additional proteins, including galectin-1 and galectin-3, are also found in the SMN-SM complex. The SMN-Sm complex is involved in spliceosomal snRNP assembly in the cytoplasm. GO:0010748 negative regulation of long-chain fatty acid import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010748 negative regulation of plasma membrane long-chain fatty acid transport Any process that decreases the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane. CHEBI:139419 beta-D-fructofuranose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139419 GO:0009750 response to fructose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009750 response to fructose stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus. GO:0009751 response to salicylic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009751 response to salicylic acid stimulus|response to salicylate Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salicylic acid stimulus. GO:0009752 detection of salicylic acid stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009752 perception of salicylic acid stimulus The series of events in which a salicylic acid stimulus is received by a cell and converted into a molecular signal. GO:0010741 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010741 GO:0009753 response to jasmonic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009753 response to jasmonic acid stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus. GO:0010742 macrophage derived foam cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010742 The process in which a monocyte acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions. GO:0009754 detection of jasmonic acid stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009754 perception of jasmonic acid stimulus The series of events in which a jasmonic acid stimulus is received by a cell and converted into a molecular signal. Series of events required for a jasmonic acid stimulus to be detected and converted to a signal molecule. GO:0034710 inhibin complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034710 Interacting selectively and non-covalently with an inhibin complex, a dimer of one inhibin-alpha subunit and one inhibin-beta subunit. GO:0034711 inhibin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034711 inhibin monomer binding|inhibin beta-B binding|inhibin beta-A binding|inhibin alpha binding Interacting selectively and non-covalently with an inhibin monomer, any of the polypeptides that combine to form activin and inhibin dimers. GO:0009755 hormone-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009755 hormone mediated signalling A series of molecular signals mediated by the detection of a hormone. GO:0010740 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010740 UBERON:0004921 subdivision of digestive tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004921 alimentary system subdivision|subdivision of alimentary system|intestinal tract|segment of intestinal tract A proximal-distal subdivision of the digestive tract. GO:0009756 carbohydrate mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009756 carbohydrate mediated signalling A series of molecular signals mediated by the detection of carbohydrate. UBERON:0004922 postnatal subventricular zone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004922 subventricular zone|SEZ|adult subventricular zone|postnatal subependymal zone|brain subventricular zone|subependymal plate|subventricular zone of brain|subependymal layer|postnatal subventricular zone|subependymal zone|SVZ|postnatal subependymal plate|postnatal subependymal layer A mitotically active layer of cells surrounding the brain ventricles in the adult that consists of migrating neuroblasts, astrocytes and transitory amplifying progenitor cells[MP]. GO:0009757 hexose mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009757 hexose mediated signalling A series of molecular signals mediated by the detection of hexose. GO:0009758 carbohydrate utilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009758 sugar utilization A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary carbohydrate sources,usually glucose, and then activates genes to scavenge the last traces of the primary carbohydrate source and to transport and metabolize alternate carbohydrate sources. The utilization process begins when the cell or organism detects carbohydrate levels, includes the activation of genes whose products detect, transport or metabolize carbohydrates, and ends when the carbohydrate is incorporated into the cell or organism's metabolism. GO:0009759 indole glucosinolate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009759 indole glucosinolate anabolism|indole glucosinolate synthesis|indole glucosinolate formation|indole glucosinolate biosynthesis The chemical reactions and pathways resulting in the formation of indole glucosinolates, sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan. CHEBI:139413 1-oleoyl-2-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139413 CHEBI:33173 benzimidazolide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33173 UBERON:0004907 lower digestive tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004907 lower gastrointestinal tract|gut|lower GI tract The region of the digestive tract extending from the beginning of the intestines to the anus[GO - gut definition]. GO:0034709 methylosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034709 20S methyltransferase complex|20S methylosome A large (20 S) protein complex that possesses protein arginine methyltransferase activity and modifies specific arginines to dimethylarginines in the arginine- and glycine-rich domains of several spliceosomal Sm proteins, thereby targeting these proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein (snRNP) core particles. Proteins found in the methylosome include the methyltransferase JBP1 (PRMT5), pICln (CLNS1A), MEP50 (WDR77), and unmethylated forms of SM proteins that have RG domains. UBERON:0004908 upper digestive tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004908 upper GI tract|upper gastrointestinal tract The region of the digestive tract extending from the mouth cavity through pharynx esophagus stomach and duodenum. UBERON:0004905 articulation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004905 joint Anatomical cluster that connects two or more adjacent skeletal elements or hardened body parts. UBERON:0004906 ectodermal part of digestive tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004906 gut ectoderm|ectodermal gut A portion of the gut that is derived from ectoderm. UBERON:0004904 neuron projection bundle connecting eye with brain biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004904 optic nerve (generic)|optic nerve A neuron projection bundle that connects the retina or its analog in the eye with the brain. This includes the vertebrate optic nerve (not truly a nerve) as well as analogous structures such as the Bolwig nerve in Drosophila UBERON:0004901 right lung lobar bronchus mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004901 The right lung lobar bronchus mesenchyme is a type of tissue made up of loosely-packed mesenchymal cells in the right lung lobar bronchus UBERON:0004902 urogenital sinus epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004902 epithelium of urogenital sinus|UGE The fetal urogenital sinus (from which the prostate derives) is a simple cylinder of stratified basal epithelium, surrounded by mesenchyme and positioned between the embryonic bladder and pelvic urethra GO:0034701 tripeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034701 EC:3.4.13.-|MetaCyc:3.4.11.4-RXN Catalysis of the hydrolysis of a tripeptide. GO:0010756 positive regulation of plasminogen activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010756 Any process that increases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin. GO:0010757 negative regulation of plasminogen activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010757 inhibition of plasminogen activation Any process that decreases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin. GO:0034702 ion channel complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034702 A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient. GO:0034703 cation channel complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034703 An ion channel complex through which cations pass. GO:0010754 negative regulation of cGMP-mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010754 negative regulation of cGMP-mediated signalling Any process that decreases the rate, frequency or extent of cGMP-mediated signaling. cGMP-mediated signaling is a series of molecular signals in which a cell uses cyclic GMP to convert an extracellular signal into a response. GO:0010755 regulation of plasminogen activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010755 Any process that modulates the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin. GO:0034704 calcium channel complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034704 An ion channel complex through which calcium ions pass. GO:0034705 potassium channel complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034705 An ion channel complex through which potassium ions pass. GO:0034706 sodium channel complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034706 An ion channel complex through which sodium ions pass. GO:0034707 chloride channel complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034707 An ion channel complex through which chloride ions pass. GO:0010758 regulation of macrophage chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010758 Any process that modulates the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus. UBERON:0004909 epithelium of gonad biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004909 gonadal epithelium|gonadal sheath|gonad epithelium An epithelium surrounding a gonad. GO:0034708 methyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034708 A protein complex that possesses methyltransferase activity. GO:0010759 positive regulation of macrophage chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010759 Any process that increases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus. CHEBI:33187 oxomalononitrile biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33187 OBO:GOCHE_26672 substance with siderophore role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_26672 GO:0009760 C4 photosynthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009760 Wikipedia:C4_carbon_fixation The combination of atmospheric CO2 with a 3-carbon molecule phosphoenol pyruvate (PEP) in the mesophyll cells to make a 4-carbon acid which is immediately converted to malic acid. The malic acid is then passed across to the bundle sheath cells where it is broken down again to pyruvic acid and CO2. The acid is passed back to the mesophyll cells to be used again, while the CO2 is fed into the reductive pentose-phosphate cycle (Calvin cycle) and converted into sugar and starch. CHEBI:33189 hydrazonomalononitrile biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33189 GO:0009761 CAM photosynthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009761 Wikipedia:Crassulacean_acid_metabolism The combination of atmospheric CO2 with a 3-carbon molecule phosphoenol pyruvate (PEP) to make malic acid. The malic acid is then passed into the vacuole where it is stored until daylight, when it is shuttled back out to be used as a substrate in the light reaction of photosynthesis. GO:0009762 NADP-malic enzyme C4 photosynthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009762 MetaCyc:PWY-241 The process of C4 photosynthesis, as it occurs in plants in which the enzyme decarboxylating C4 acids in the bundle sheath is NADP-malic enzyme. CHEBI:140403 N-acyl-1-[(1Z)-alkenyl]-sn-glycero-3-phosphoethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140403 GO:0010752 regulation of cGMP-mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010752 regulation of cGMP-mediated signalling Any process that modulates the rate, frequency or extent of cGMP-mediated signaling. cGMP-mediated signaling is a series of molecular signals in which a cell uses cyclic GMP to convert an extracellular signal into a response. GO:0009763 NAD-malic enzyme C4 photosynthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009763 The process of C4 photosynthesis, as it occurs in plants in which the enzyme decarboxylating C4 acids in the bundle sheath is NAD-malic enzyme. GO:0010753 positive regulation of cGMP-mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010753 positive regulation of cGMP-mediated signalling Any process that increases the rate, frequency or extent of cGMP-mediated signaling. cGMP-mediated signaling is a series of molecular signals in which a cell uses cyclic GMP to convert an extracellular signal into a response. GO:0009764 PEP carboxykinase C4 photosynthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009764 The process of C4 photosynthesis, as it occurs in plants in which the enzyme decarboxylating C4 acids in the bundle sheath is phosphoenolpyruvate carboxykinase (PEPCK). GO:0009765 photosynthesis, light harvesting biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009765 energy dissipation Absorption and transfer of the energy absorbed from light photons between photosystem reaction centers. GO:0010750 positive regulation of nitric oxide mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010750 positive regulation of nitric oxide-mediated signal transduction Any process that increases the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is a series of molecular signals mediated by the detection of nitric oxide (NO). GO:0010751 negative regulation of nitric oxide mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010751 negative regulation of nitric oxide-mediated signal transduction Any process that decreases the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is a series of molecular signals mediated by the detection of nitric oxide (NO). GO:0009766 primary charge separation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009766 In the photosynthetic reaction centers, primary charge separation is initiated by the excitation of a molecule followed by the transfer of an electron to an electron acceptor molecule following energy transfer from light harvesting complexes. GO:0034700 allulose 6-phosphate 3-epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034700 RHEA:28426|MetaCyc:RXN0-304 Catalysis of the reaction: D-allulose 6-phosphate = D-fructose 6-phosphate. GO:0009767 photosynthetic electron transport chain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009767 photosynthetic electron transport in plastoquinone|photosynthetic electron transport in cytochrome b6/f|electron carrier, chlorophyll electron transport system|photosynthetic electron transport in plastocyanin A process, occurring as part of photosynthesis, in which light provides the energy for a series of electron carriers to operate together to transfer electrons and generate a transmembrane electrochemical gradient. UBERON:0004910 epithelium of male gonad biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004910 testis sheath|testis epithelium An epithelium surrounding a testis. UBERON:0004911 epithelium of female gonad biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004911 ovarian sheath|ovarian epithelium|ovary epithelium An epithelium surrounding an ovary. GO:0009768 photosynthesis, light harvesting in photosystem I biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009768 After a photon of light is absorbed by one of the many chlorophyll molecules, in one of the light-harvesting complexes of an antenna on photosystem I, some of the absorbed energy is transferred to the pair of chlorophyll molecules in the reaction center. GO:0009769 photosynthesis, light harvesting in photosystem II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009769 After a photon of light is absorbed by one of the many chlorophyll molecules, in one of the light-harvesting complexes of an antenna on photosystem II, some of the absorbed energy is transferred to the pair of chlorophyll molecules in the reaction center. CHEBI:33184 long-chain fatty acyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33184 CHEBI:33186 malononitrile biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33186 GO:0010729 positive regulation of hydrogen peroxide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010729 positive regulation of hydrogen peroxide biosynthesis Any process that increases the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA. GO:0044104 2,5-dioxovalerate dehydrogenase (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044104 2,5-dioxopentanoate dehydrogenase (NAD+) activity|2,5-dioxopentanoate:NAD+ 5-oxidoreductase activity Catalysis of the reaction: 2,5-dioxopentanoate + NAD+ + H2O = 2-oxoglutarate + NADH + H+. GO:0010723 positive regulation of transcription from RNA polymerase II promoter in response to iron biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010723 Any process that increases the rate of transcription from an RNA polymerase II promoter in response to an iron stimulus. GO:0010724 regulation of definitive erythrocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010724 regulation of definitive erythropoiesis|regulation of definitive RBC differentiation|regulation of definitive red blood cell differentiation Any process that modulates the rate, frequency, or extent of definitive erythrocyte differentiation. Definitive erythrocyte differentiation occurs as part of the process of definitive hemopoiesis. GO:0044105 L-xylulose reductase (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044105 EC:1.1.1.10 Catalysis of the reaction: xylitol + NAD+ = L-xylulose + NADH + H+. GO:0044102 purine deoxyribosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044102 purine 2'-deoxyribosyltransferase activity|PTD Catalysis of deoxyribose exchange between purine deoxyribonucleoside as a donor and purine base as an acceptor. GO:0010721 negative regulation of cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010721 Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. GO:0010722 regulation of ferrochelatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010722 Any process that modulates the frequency, rate or extent of ferrochelatase activity; catalysis of the reaction: protoporphyrin + Fe2+ = protoheme + 2 H+. GO:0044103 L-arabinose 1-dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044103 EC:1.1.1.376 Catalysis of the reaction: L-arabinose + NADP+ = L-arabinono-1,4-lactone + NADPH + H+. GO:0044100 sporoplasm biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044100 The complex infective apparatus corresponding to the central mass of cytoplasm within a spore that is injected into a host cell by various parasitic microorganisms. GO:0010727 negative regulation of hydrogen peroxide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010727 negative regulation of hydrogen peroxide metabolism Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide. GO:0010728 regulation of hydrogen peroxide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010728 regulation of hydrogen peroxide biosynthesis Any process that modulates the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA. GO:0044101 (R)-citramalyl-CoA lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044101 EC:4.1.3.46|MetaCyc:RXN-8967 R-citramalyl-CoA lyase activity|Ccl Catalysis of the reaction: (R)-citramalyl-CoA = pyruvate + acetyl-CoA. GO:0010725 regulation of primitive erythrocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010725 regulation of primitive erythropoeisis|regulation of primitive RBC differentiation|regulation of primitive red blood cell differentiation Any process that modulates the rate, frequency, or extent of primitive erythrocyte differentiation. Primitive erythrocyte differentiation occurs as part of the process of primitive hemopoiesis. GO:0010726 positive regulation of hydrogen peroxide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010726 positive regulation of hydrogen peroxide metabolism Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide. UBERON:0004980 mucosa of ureter biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004980 tunica mucosa (ureter)|ureter mucosa of organ|ureteral mucosa|mucosal layer of ureter|tunica mucosa ureteris|ureter mucous membrane|ureter organ mucosa|organ mucosa of ureter|ureteric mucosa|ureter mucosa|mucosa of organ of ureter|mucous membrane of ureter A mucosa that is part of a ureter [Automatically generated definition]. GO:0009730 detection of carbohydrate stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009730 perception of carbohydrate stimulus The series of events in which a carbohydrate stimulus is received by a cell and converted into a molecular signal. GO:0044108 cellular alcohol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044108 The chemical reactions and pathways resulting in the formation of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom, carried out at the level of an individual cell. GO:0010720 positive regulation of cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010720 Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. GO:0044109 cellular alcohol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044109 The chemical reactions and pathways resulting in the breakdown of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom, occurring at the level of the individual cell. GO:0009731 detection of sucrose stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009731 perception of sucrose stimulus The series of events in which a sucrose stimulus is received by a cell and converted into a molecular signal. GO:0044106 cellular amine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044106 The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group, as carried out by individual cells. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. GO:0009732 detection of hexose stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009732 perception of hexose stimulus The series of events in which a stimulus from a hexose is received and converted into a molecular signal. GO:0044107 cellular alcohol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044107 The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom, as carried out by individual cells. GO:0009733 response to auxin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009733 response to auxin stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus. GO:0009734 auxin-activated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009734 auxin-regulated transcription|auxin mediated signalling|auxin signal transduction|auxin signaling|auxin mediated signaling pathway A series of molecular signals generated by the binding of the plant hormone auxin to a receptor, and ending with modulation of a downstream cellular process, e.g. transcription. GO:0009735 response to cytokinin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009735 response to cytokinin stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokinin stimulus. UBERON:0004988 mucosa of cystic duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004988 mucosa of organ of cystic duct|cystic duct organ mucosa|organ mucosa of cystic duct|cystic duct mucosa of organ|cystic duct mucous membrane|cystic duct mucosa|mucous membrane of cystic duct|cystic ductal mucosa A mucosa that is part of a cystic duct [Automatically generated definition]. UBERON:0004985 mucosa of ejaculatory duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004985 ejaculatory duct mucosa of organ|ejaculatory duct mucous membrane|ejaculatory ductal mucosa|organ mucosa of ejaculatory duct|ejaculatory duct organ mucosa|mucosa of organ of ejaculatory duct|mucous membrane of ejaculatory duct|ejaculatory duct mucosa A mucosa that is part of a ejaculatory duct [Automatically generated definition]. GO:0009736 cytokinin-activated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009736 cytokinin mediated signalling|cytokinin mediated signaling pathway|cytokinin signaling A series of molecular signals generated by the binding of a cytokinin to a receptor, and ending with regulation of a downstream cellular process, e.g. transcription. UBERON:0004986 mucosa of deferent duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004986 vas deferen mucous membrane|sperm duct mucosa|tunica mucosa (ductus deferens)|vas deferens organ mucosa|sperm duct mucous membrane|vas deferen mucosa|mucosa of organ of vas deferens|mucous membrane of deferent duct|ductus deferens mucosa of organ|organ mucosa of ductus deferens|mucosa of vas deferens|mucosa of organ of deferent duct|mucous membrane of vas deferens|ductus deferens organ mucosa|organ mucosa of sperm duct|deferent duct mucosa|mucous membrane of vas deferen|ductus deferens mucous membrane|mucosa of vas deferen|vas deferens mucosa of organ|mucosa of organ of vas deferen|sperm duct organ mucosa|vas deferens mucosa|vas deferens mucous membrane|organ mucosa of deferent duct|deferent duct mucosa of organ|mucosa of organ of sperm duct|vas deferen organ mucosa|mucous membrane of ductus deferens|deferent ductal mucosa|mucosa of ductus deferens|tunica mucosa ductus deferentis|mucosa of sperm duct|ductus deferens mucosa|organ mucosa of vas deferens|deferent duct mucous membrane|organ mucosa of vas deferen|mucosa of organ of ductus deferens|mucous membrane of sperm duct|vas deferen mucosa of organ|deferent duct organ mucosa|sperm duct mucosa of organ A mucosa that is part of a vas deferens [Automatically generated definition]. GO:0009737 response to abscisic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009737 response to abscisic acid stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus. UBERON:0004983 mucosa of vagina biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004983 vagina mucosa|vagina mucous membrane|organ mucosa of vagina|vaginal mucosa|vagina organ mucosa|mucosa of organ of vagina|tunica mucosa vaginae|mucous membrane of vagina|vagina mucosa of organ A mucosa that is part of a vagina [Automatically generated definition]. GO:0009738 abscisic acid-activated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009738 abscisic acid mediated signalling|abscisic acid-mediated signaling pathway|abscisic acid signal transduction|ABA signal transduction|ABA signaling A series of molecular signals generated by the binding of the plant hormone abscisic acid (ABA) to a receptor, and ending with modulation of a cellular process, e.g. transcription. UBERON:0004984 mucosa of seminal vesicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004984 organ mucosa of seminal gland|seminal gland mucosa of organ|seminal vesicle mucous membrane|seminal vesicle mucosa|seminal gland mucous membrane|mucous membrane of seminal vesicle|seminal gland organ mucosa|mucosa of organ of seminal vesicle|mucous membrane of seminal gland|tunica mucosa glandulae vesiculosae|mucosa of seminal gland|seminal vesicle organ mucosa|mucosa of organ of seminal gland|seminal vesicle mucosa of organ|organ mucosa of seminal vesicle|seminal gland mucosa A mucosa that is part of a seminal vesicle [Automatically generated definition]. GO:0009739 response to gibberellin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009739 response to gibberellin stimulus|response to gibberellic acid stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gibberellin stimulus. CHEBI:47795 (R)-dihydrocamalexic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47795 CHEBI:47796 (S)-dihydrocamalexic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47796 CHEBI:47798 xi-progoitrin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47798 CHEBI:47799 calcitetrol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47799 GO:0044115 development of symbiont involved in interaction with host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044115 development of symbiont during interaction with host The progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0010734 negative regulation of protein glutathionylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010734 negative regulation of protein amino acid glutathionylation Any process that decreases the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage. GO:0010735 positive regulation of transcription via serum response element binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010735 Any process that increases the frequency, rate or extent of the specifically regulated synthesis of RNA from DNA encoding a specific set of genes as a result of a transcription factor interacting with a serum response element (SRE). A serum response element is a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum. GO:0044116 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044116 GO:0010732 regulation of protein glutathionylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010732 regulation of protein amino acid glutathionylation Any process that modulates the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage. GO:0044113 development in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044113 development in other organism during symbiotic interaction The progression of an organism from an initial condition to a later condition, occurring within the cells or tissues of a second organism, where the two organisms are in a symbiotic interaction. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down the tissue of the second organism. GO:0044114 development of symbiont in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044114 development of symbiont in host intercellular space|development of symbiont in host vascular tissue The progression of an organism from an initial condition to a later condition, occurring within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down host tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0010733 positive regulation of protein glutathionylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010733 positive regulation of protein amino acid glutathionylation Any process that increases the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage. CHEBI:47790 furofuran biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47790 GO:0010738 regulation of protein kinase A signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010738 regulation of PKA signaling cascade|regulation of protein kinase A signalling cascade|regulation of protein kinase A signaling cascade Any process that modulates the rate, frequency, or extent of protein kinase A signaling. PKA signaling is the series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound. CHEBI:47791 phenylacetaldehyde oxime biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47791 GO:0044111 development involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044111 development on or near surface of other organism involved in symbiotic interaction|development during symbiotic interaction|development on or near surface of other organism during symbiotic interaction The progression of an organism from an initial condition to a later condition, occurring when the organism is in a symbiotic interaction. GO:0044112 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044112 GO:0010739 positive regulation of protein kinase A signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010739 positive regulation of PKA signaling cascade|positive regulation of protein kinase A signaling cascade|positive regulation of protein kinase A signalling cascade Any process that increases the rate, frequency, or extent of protein kinase A signaling. PKA signaling is the series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound. GO:0010736 serum response element binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010736 Interacting selectively and non-covalently with the serum response element (SRE), a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum. CHEBI:47793 (E)-phenylacetaldehyde oxime biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47793 GO:0010737 protein kinase A signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010737 protein kinase A signaling cascade|PKA signaling cascade|protein kinase A signal transduction|protein kinase A signalling cascade A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound. GO:0044110 obsolete growth involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044110 growth on or near surface of other organism involved in symbiotic interaction|growth on or near surface of other organism during symbiotic interaction|growth during symbiotic interaction OBSOLETE. The increase in size or mass of an organism occurring when the organism is in a symbiotic interaction. CHEBI:47794 dihydrocamalexic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47794 GO:0009740 gibberellic acid mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009740 gibberellic acid signaling|GA-signaling|gibberellic acid mediated signalling A series of molecular signals mediated by the detection of gibberellic acid. GO:0010730 negative regulation of hydrogen peroxide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010730 negative regulation of hydrogen peroxide biosynthesis Any process that decreases the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA. GO:0009741 response to brassinosteroid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009741 response to brassinosteroid stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brassinosteroid stimulus. GO:0044119 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044119 GO:0010731 protein glutathionylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010731 protein amino acid glutathionylation The protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage. GO:0009742 brassinosteroid mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009742 brassinosteroid mediated signalling A series of molecular signals mediated by the detection of brassinosteroid. GO:0044117 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044117 GO:0009743 response to carbohydrate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009743 response to carbohydrate stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus. GO:0009744 response to sucrose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009744 response to sucrose stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus. GO:0044118 development of symbiont in host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044118 The progression of the symbiont from an initial condition to a later condition, occurring in its host's cell. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0009745 sucrose mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009745 sucrose mediated signalling A series of molecular signals mediated by the detection of sucrose. GO:0009746 response to hexose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009746 response to hexose stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus. CHEBI:139400 N-acyllysophosphatidyl-L-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139400 CHEBI:139401 N-hexadecanoyl-1-[(1Z)-octadecenoyl]-2-oleoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139401 GO:0009747 hexokinase-dependent signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009747 hexokinase-dependent signalling A series of molecular signals mediated by hexose and dependent on the detection of hexokinase. GO:0009748 hexokinase-independent signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009748 hexokinase-independent signalling A series of molecular signals mediated by hexose and independent of hexokinase. GO:0009749 response to glucose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009749 response to glucose stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus. CHEBI:33163 dec-9-enoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33163 GO:0010709 heteroduplex formation involved in double-strand break repair via synthesis-dependent strand annealing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010709 The formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules resulting in the error-free repair of a double-strand break without the exchange of adjacent sequences. CHEBI:47784 nucleotide conjugate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47784 GO:0010707 globoside biosynthetic process via lactosylceramide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010707 globoside biosynthesis via lactosylceramide biosynthesis|biosynthesis of lactosylceramide precursor to globoside|lactosylceramide biosynthesis leading to globoside|lactosylceramide biosynthetic process leading to globoside The chemical reactions and pathways resulting in the formation of globosides that begins with the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. CHEBI:47786 16-oxo steroid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47786 GO:0010708 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010708 CHEBI:47787 11-oxo steroid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47787 CHEBI:47788 3-oxo steroid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47788 CHEBI:47789 7-oxo steroid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47789 GO:0010701 positive regulation of norepinephrine secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010701 Any process that increases the frequency, rate or extent of the regulated release of norepinephrine. GO:0044126 obsolete regulation of growth of symbiont in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044126 OBSOLETE. Any process in which the symbiont regulates the increase in its size or mass within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down. The host is defined as the larger of the organisms involved in the symbiotic interaction. GO:0044127 regulation of development of symbiont in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044127 Any process in which the symbiont regulates its progression from an initial condition to a later condition, within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down. The host is defined as the larger of the organisms involved in the symbiotic interaction. GO:0010702 obsolete regulation of histolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010702 OBSOLETE. Any process that modulates the rate, frequency or extent of the breakdown of tissues; usually, if not always, accompanied by cell death. GO:0044124 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044124 GO:0044125 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044125 GO:0010700 negative regulation of norepinephrine secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010700 Any process that decreases the frequency, rate or extent of the regulated release of norepinephrine. GO:0010705 meiotic DNA double-strand break processing involved in reciprocal meiotic recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010705 The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang occurs resulting in double strand break formation and repair through a double Holliday junction intermediate. GO:0044122 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044122 GO:0044123 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044123 GO:0010706 ganglioside biosynthetic process via lactosylceramide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010706 biosynthesis of lactosylceramide precursor to ganglioside|ganglioside biosynthesis via lactosylceramide biosynthesis|lactosylceramide biosynthetic process leading to ganglioside|lactosylceramide biosynthesis leading to ganglioside The chemical reactions and pathways resulting in the formation of gangliosides that begins with the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. CHEBI:47781 desipramine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47781 GO:0044120 development of symbiont in host vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044120 development of symbiont in host organelle The progression of the symbiont from an initial condition to a later condition, occurring in a host vacuole. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0010703 obsolete negative regulation of histolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010703 inhibition of histolysis|down-regulation of histolysis|downregulation of histolysis|down regulation of histolysis OBSOLETE. Any process that decreases the rate, frequency or extent of the breakdown of tissues; usually, if not always, accompanied by cell death. GO:0044121 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044121 GO:0010704 meiotic DNA double-strand break processing involved in meiotic gene conversion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010704 The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang resulting in the transfer of genetic information from one helix to another. CHEBI:47783 cyclopentafuran biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47783 GO:0009710 tropane alkaloid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009710 tropane alkaloid anabolism|tropane alkaloid synthesis|tropane alkaloid formation|tropane alkaloid biosynthesis The chemical reactions and pathways resulting in the breakdown of tropane alkaloids, compounds containing the 8-methyl-8-azabicyclo(3.2.1)octane ring system. GO:0044128 obsolete positive regulation of growth of symbiont in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044128 OBSOLETE. Any process in which the symbiont activates, maintains or increases its size or mass within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction. GO:0009711 purine alkaloid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009711 purine alkaloid formation|purine alkaloid anabolism|purine alkaloid synthesis|purine alkaloid biosynthesis The chemical reactions and pathways resulting in the breakdown of purine alkaloids, compounds derived from purine and composed of an N-containing double ring structure. GO:0044129 positive regulation of development of symbiont in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044129 Any process in which the symbiont activates or maintains its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction. GO:0009712 catechol-containing compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009712 catechol metabolism|catechol metabolic process The chemical reactions and pathways involving a compound containing a pyrocatechol (1,2-benzenediol) nucleus or substituent. GO:0009713 catechol-containing compound biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009713 catechol formation|catechol biosynthesis|catechol biosynthetic process|catechol anabolism|catechol synthesis The chemical reactions and pathways resulting in the formation of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent. GO:0009714 chalcone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009714 chalcone metabolism The chemical reactions and pathways involving chalcones, phenyl steryl ketone or its hydroxylated derivatives. GO:0009715 chalcone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009715 chalcone biosynthesis|chalcone anabolism|chalcone synthesis|chalcone formation The chemical reactions and pathways resulting in the formation of chalcone, phenyl steryl ketone or its hydroxylated derivatives. GO:0009716 flavonoid phytoalexin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009716 flavonoid phytoalexin formation|flavonoid phytoalexin biosynthesis|flavonoid phytoalexin anabolism|flavonoid phytoalexin synthesis The chemical reactions and pathways resulting in the formation of flavonoid phytoalexins, a group of water-soluble phenolic derivatives containing a flavan skeleton, which possess antibiotic activity and are produced by plant tissues in response to infection. GO:0009717 isoflavonoid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009717 isoflavonoid biosynthesis|isoflavonoid synthesis|isoflavonoid formation|isoflavonoid anabolism The chemical reactions and pathways resulting in the formation of isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids. GO:0009718 anthocyanin-containing compound biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009718 anthocyanin biosynthesis|anthocyanin biosynthetic process|anthocyanin anabolism|anthocyanin synthesis|anthocyanin formation The chemical reactions and pathways resulting in the formation of anthocyanins, any member of a group of intensely colored soluble glycosides of anthocyanidins. GO:0009719 response to endogenous stimulus biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate|goslim_plant http://purl.obolibrary.org/obo/GO_0009719 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism. CHEBI:47773 very-low-density lipoprotein cholesterol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47773 GO:0044130 obsolete negative regulation of growth of symbiont in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044130 OBSOLETE. Any process in which the symbiont stops, prevents or reduces its increase in size or mass within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction. CHEBI:47774 low-density lipoprotein cholesterol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47774 GO:0010718 positive regulation of epithelial to mesenchymal transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010718 Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. CHEBI:47775 high-density lipoprotein cholesterol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47775 GO:0010719 negative regulation of epithelial to mesenchymal transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010719 Any process that decreases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. CHEBI:47776 very-low-density lipoprotein triglyceride biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47776 CHEBI:47777 1,3-diglyceride biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47777 CHEBI:47778 glyceride biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47778 UBERON:0004945 submucosa of neck of urinary bladder biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004945 submucosa of bladder neck|neck of urinary bladder submucosa|submucosa of vesical neck|submucosa of urinary bladder neck|neck of bladder submucosa|bladder neck submucosa|vesical neck submucosa|urinary bladder neck submucosa|submucosa of neck of bladder A submucosa that is part of a neck of urinary bladder [Automatically generated definition]. CHEBI:47779 aminoglycoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47779 GO:0044137 obsolete growth of symbiont on or near host rhizosphere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044137 OBSOLETE. The increase in size or mass of symbiont occurring on or near its host rhizosphere. The host rhizosphere is defined as total below-ground surfaces of a plant as a habitat for its symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0010712 regulation of collagen metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010712 regulation of collagen metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. GO:0044138 obsolete modulation of development of symbiont on or near host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044138 OBSOLETE. Any process in which the symbiont regulates its progression from an initial condition to a later condition, on or near the cells or tissues of the host organism. GO:0010713 negative regulation of collagen metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010713 Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. GO:0044135 obsolete growth of symbiont on or near host phyllosphere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044135 OBSOLETE. The increase in size or mass of symbiont occurring on or near its host phyllosphere. The host phyllosphere is defined as total above-ground surfaces of a plant as a habitat for symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0010710 regulation of collagen catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010710 regulation of collagen degradation|regulation of collagen breakdown|regulation of collagen catabolism Any process that modulates the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix. GO:0010711 negative regulation of collagen catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010711 negative regulation of collagen breakdown|down-regulation of collagen catabolic process|negative regulation of collagen catabolism|downregulation of collagen catabolic process|down regulation of collagen catabolic process|inhibition of collagen catabolic process|negative regulation of collagen degradation Any process that decreases the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix. GO:0044136 obsolete development of symbiont on or near host rhizosphere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044136 OBSOLETE. The progression of the symbiont from an initial condition to a later condition, occurring on or near its host rhizosphere. The host rhizosphere is defined as total below-ground surfaces of a plant as a habitat for its symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0044133 obsolete growth of symbiont on or near host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044133 OBSOLETE. The increase in size or mass of a symbiont within the cells or tissues of its host organism. GO:0010716 negative regulation of extracellular matrix disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010716 down-regulation of extracellular matrix disassembly|downregulation of extracellular matrix disassembly|down regulation of extracellular matrix disassembly|inhibition of extracellular matrix disassembly|negative regulation of extracellular matrix degradation|negative regulation of extracellular matrix breakdown Any process that decreases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix. GO:0044134 obsolete development of symbiont on or near host phyllosphere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044134 OBSOLETE. The progression of the symbiont from an initial condition to a later condition, occurring on or near its host phyllosphere. The host phyllosphere is defined as total above-ground surfaces of a plant as a habitat for symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0010717 regulation of epithelial to mesenchymal transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010717 Any process that modulates the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. GO:0044131 negative regulation of development of symbiont in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044131 Any process in which the symbiont stops, prevents or reduces its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction. CHEBI:47771 beta-tocopherol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47771 GO:0010714 positive regulation of collagen metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010714 positive regulation of collagen metabolism Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. CHEBI:47772 delta-tocopherol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47772 GO:0010715 regulation of extracellular matrix disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010715 regulation of extracellular matrix breakdown|regulation of extracellular matrix degradation Any process that modulates the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix. GO:0044132 obsolete development of symbiont on or near host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044132 OBSOLETE. The progression of a symbiont from an initial condition to a later condition, within the cells or tissues of its host organism. CHEBI:33143 chromic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33143 CHEBI:33144 hydrogenchromate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33144 CHEBI:33145 boron oxoacid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33145 GO:0009720 detection of hormone stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009720 perception of hormone stimulus The series of events in which a hormone stimulus is received by a cell and converted into a molecular signal. GO:0044139 obsolete modulation of growth of symbiont on or near host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044139 OBSOLETE. Any process in which the symbiont regulates the increase in its size or mass on or near the cells or tissues of the host organism. GO:0009721 detection of auxin stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009721 perception of auxin stimulus The series of events in which an auxin stimulus is received by a cell and converted into a molecular signal. GO:0009722 detection of cytokinin stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009722 perception of cytokinin stimulus The series of events in which a cytokinin stimulus is received by a cell and converted into a molecular signal. GO:0009723 response to ethylene biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009723 response to ethylene stimulus|response to ethene stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus. GO:0009724 detection of abscisic acid stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009724 perception of abscisic acid stimulus The series of events in which an abscisic acid stimulus is received by a cell and converted into a molecular signal. UBERON:0004952 submucosa of bronchiole biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004952 submucosa of lobular bronchiole|bronchiole submucosa|lobular bronchiole submucosa A submucosa that is part of a bronchiole [Automatically generated definition]. GO:0009725 response to hormone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009725 response to hormone stimulus|growth regulator Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus. GO:0009726 detection of endogenous stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009726 perception of endogenous stimulus The series of events in which an endogenous stimulus is received by a cell and converted into a molecular signal. UBERON:0004950 submucosa of lobar bronchus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004950 lobar bronchial submucosa|submucosa of secondary bronchus|lobar bronchus submucosa|secondary bronchus submucosa A submucosa that is part of a lobar bronchus [Automatically generated definition]. GO:0009727 detection of ethylene stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009727 detection of ethene stimulus|perception of ethene stimulus|perception of ethylene stimulus The series of events in which an ethylene (ethene) stimulus is received by a cell and converted into a molecular signal. GO:0009728 detection of gibberellic acid stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009728 perception of gibberellic acid stimulus The series of events in which a gibberellic acid stimulus is received by a cell and converted into a molecular signal. UBERON:0004951 submucosa of segmental bronchus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004951 segmental bronchus submucosa|submucosa of tertiary bronchus|tertiary bronchus submucosa|segmental bronchial submucosa A submucosa that is part of a segmental bronchus [Automatically generated definition]. CHEBI:33140 pyrazolium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33140 GO:0009729 detection of brassinosteroid stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009729 perception of brassinosteroid stimulus The series of events in which a brassinosteroid stimulus is received by a cell and converted into a molecular signal. GO:0019184 nonribosomal peptide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019184 non-ribosomal peptide biosynthesis|non-ribosomal peptide biosynthetic process|non-ribosomal peptide synthesis|non-ribosomal peptide formation|nonribosomal peptide anabolism|nonribosomal peptide biosynthesis|nonribosomal peptide synthesis|nonribosomal peptide formation|nonribosomal peptide synthetase The biosynthetic process in which peptide bond formation occurs in the absence of the translational machinery. Examples include the synthesis of antibiotic peptides, and glutathione. GO:0019185 snRNA-activating protein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019185 SNAPc A protein complex that recognizes the proximal sequence element of RNA polymerase II and III snRNA promoters. GO:0019182 histamine-gated chloride channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019182 Enables the transmembrane transfer of a chloride ion by a channel that opens when histamine has been bound by the channel complex or one of its constituent parts. CHEBI:72720 flavonoid oligomer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72720 GO:0019183 histamine-gated chloride channel complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019183 A protein complex that forms a transmembrane channel through which chloride ions may pass in response to histamine binding to the channel complex or one of its constituent parts. GO:0019180 dTDP-4-amino-4,6-dideoxygalactose transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019180 MetaCyc:2.6.1.59-RXN|EC:2.6.1.59|KEGG_REACTION:R04438|RHEA:10368 thymidine diphosphoaminodideoxygalactose aminotransferase activity|dTDP-4-amino-4,6-dideoxygalactose aminotransferase activity|dTDP-4,6-dideoxy-D-galactose:2-oxoglutarate aminotransferase activity|dTDP-fucosamine aminotransferase activity|thymidine diphosphate 4-keto-6-deoxy-D-glucose transaminase activity Catalysis of the reaction: 2-oxoglutarate + dTDP-4-amino-4,6-dideoxy-D-galactose = L-glutamate + dTDP-4-dehydro-6-deoxy-D-galactose. GO:0019181 halohydrin hydrogen-halide-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019181 Catalysis of the reaction: a halohydrin = an epoxide + a hydrogen halide. CHEBI:72725 3-amino-3-deoxy-D-glucopyranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72725 CHEBI:72726 hydroxypalmitic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72726 CHEBI:72728 D-kanosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72728 GO:0019179 dTDP-4-amino-4,6-dideoxy-D-glucose transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019179 EC:2.6.1.33|MetaCyc:2.6.1.33-RXN|RHEA:19085 thymidine diphospho-4-amino-4,6-dideoxyglucose aminotransferase activity|TDP-4-oxo-6-deoxy-D-glucose transaminase activity|dTDP-4-amino-4,6-dideoxy-D-glucose:2-oxoglutarate aminotransferase activity|TDP-4-keto-6-deoxy-D-glucose transaminase activity|thymidine diphospho-4-keto-6-deoxy-D-glucose-glutamic transaminase activity|thymidine diphospho-4-keto-6-deoxy-D-glucose transaminase activity|dTDP-4-amino-4,6-dideoxy-D-glucose aminotransferase activity|thymidine diphospho-4-amino-6-deoxyglucose aminotransferase activity Catalysis of the reaction: dTDP-4-amino-4,6-dideoxy-D-glucose + 2-oxoglutarate = dTDP-4-dehydro-6-deoxy-D-glucose + L-glutamate. GO:0019177 dihydroneopterin triphosphate pyrophosphohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019177 MetaCyc:H2NEOPTERINP3PYROPHOSPHOHYDRO-RXN|RHEA:25302 Catalysis of the reaction: dihydroneopterin triphosphate = dihydroneopterin phosphate + diphosphate. GO:0019178 NADP phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019178 MetaCyc:NADPPHOSPHAT-RXN Catalysis of the reaction: H2O + NADP+ = NAD+ + phosphate. GO:0019175 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019175 GO:0019176 dihydroneopterin monophosphate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019176 RHEA:25306|MetaCyc:DIHYDRONEOPTERIN-MONO-P-DEPHOS-RXN dihydroneopterin monophosphate dephosphorylase activity Catalysis of the reaction: dihydroneopterin monophosphate = dihydroneopterin + phosphate. GO:0019195 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019195 GO:0019196 galactosamine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019196 galactosamine porter activity Enables the transfer of galactosamine from one side of a membrane to the other. Galactosamine is an aminodeoxysugar; D-galactosamine is a constituent of some glycolipids and glycosaminoglycans, commonly as its N-acetyl derivative. CHEBI:72730 flavanone glycoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72730 GO:0019193 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019193 CHEBI:72732 3-amino-3-deoxy-D-glucopyranose(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72732 GO:0019194 sorbose transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019194 sorbose porter activity Enables the transfer of sorbose from one side of a membrane to the other. Sorbose is the ketohexose xylo-2-hexulose; L-sorbose is formed by bacterial oxidation of sorbitol. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid. GO:0019191 cellobiose transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019191 cellobiose permease activity Enables the transfer of cellobiose from one side of a membrane to the other. Cellobiose, or 4-O-beta-D-glucopyranosyl-D-glucose, is a disaccharide that represents the basic repeating unit of cellulose. GO:0019192 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019192 CHEBI:72735 lysophosphatidylethanolamine 20:3 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72735 GO:0019190 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019190 CHEBI:72737 lysophosphatidylcholine 17:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72737 CHEBI:72739 hydroxyisoflavanone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72739 GO:0019188 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019188 GO:0019189 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019189 GO:0019186 acyl-CoA N-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019186 Catalysis of the transfer of an acyl group from acyl-CoA to a nitrogen atom on an acceptor molecule. CHEBI:237958 ({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(9H-purin-9-yl)oxolan-2-yl]methyl phosphonato}oxy)(phosphonatooxy)phosphinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_237958 GO:0019187 beta-1,4-mannosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019187 Catalysis of the transfer of a mannose residue to an oligosaccharide, forming a beta-(1->4) linkage. GO:0019162 pyridoxamine-oxaloacetate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019162 MetaCyc:PYROXALTRANSAM-RXN|KEGG_REACTION:R01713|RHEA:10844|EC:2.6.1.31 pyridoxamine:oxaloacetate aminotransferase activity|pyridoxamine--oxaloacetate aminotransferase activity|pyridoxamine-oxaloacetate aminotransferase activity Catalysis of the reaction: oxaloacetate + pyridoxamine = L-aspartate + pyridoxal. CHEBI:72740 methoxyisoflavanone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72740 GO:0019163 pyridoxamine-phosphate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019163 RHEA:15877|EC:2.6.1.54|MetaCyc:PYRDAMPTRANS-RXN pyridoxamine 5'-phosphate-alpha-ketoglutarate transaminase activity|pyridoxamine-phosphate aminotransferase activity|pyridoxamine 5'-phosphate transaminase activity|pyridoxamine-5'-phosphate:2-oxoglutarate aminotransferase (D-glutamate-forming)|pyridoxamine phosphate aminotransferase activity Catalysis of the reaction: pyridoxamine 5'-phosphate + 2-oxoglutarate = pyridoxal 5'-phosphate + D-glutamate. CHEBI:72741 2-arachidonyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72741 GO:0019160 NMN nucleosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019160 RHEA:23140|KEGG_REACTION:R01270|EC:3.2.2.14|MetaCyc:NMNNUCLEOSID-RXN NMNGhase activity|NMNase activity|nicotinamide-nucleotide phosphoribohydrolase activity|NMN glycohydrolase activity|nicotinamide mononucleotidase activity|nicotinamide mononucleotide nucleosidase activity Catalysis of the reaction: H(2)O + nicotinamide mononucleotide = D-ribose 5-phosphate + H(+) + nicotinamide. GO:0019161 diamine transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019161 EC:2.6.1.29|MetaCyc:DIAMTRANSAM-RXN|RHEA:18217 amine transaminase activity|diamine:2-oxoglutarate aminotransferase activity|amine-ketoacid transaminase activity|diamine aminotransferase activity|diamine-ketoglutaric transaminase activity Catalysis of the reaction: an alpha,omega-diamine + 2-oxoglutarate = an omega-aminoaldehyde + L-glutamate. CHEBI:72744 1-hexadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72744 CHEBI:72745 (E)-hexadec-2-enoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72745 CHEBI:72748 3-amino-3-deoxy-6-O-phosphono-D-glucopyranose(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72748 CHEBI:140498 dihydro-ferroheme d1(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140498 CHEBI:140497 12,18-didecarboxysiroheme(6-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140497 CHEBI:140494 O(3)-(beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-2-O-phospho-xylosyl)-L-serine(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140494 CHEBI:140495 O(3)-(beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-2-O-phospho-xylosyl)-L-serine(3-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140495 GO:0034792 hypophosphite dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034792 UM-BBD_reactionID:r1058 Catalysis of the reaction: hypophosphite + 2-oxoglutarate + O2 = succinate + phosphite + CO2. GO:0034793 cyclopropanecarboxylate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034793 UM-BBD_reactionID:r1056 Catalysis of the reaction: cyclopropanecarboxylate + CoASH = cyclopropanecarboxyl-CoA + OH-. GO:0034794 cyclopropanecarboxyl-CoA decyclase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034794 UM-BBD_reactionID:r1057|EC:5.5.1.- Catalysis of the reaction: cyclopropanecarboxyl-CoA = crotonoyl-CoA. GO:0034795 cyclohexane monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034795 MetaCyc:RXN-8697|UM-BBD_reactionID:r1059|KEGG_REACTION:R06945|EC:1.14.15.- cyclohexane hydroxylase activity|butane monooxygenase activity Catalysis of the reaction: cyclohexane + O2 + NAD(P)H + H+ = cyclohexanol + NAD(P)+ + H2O. GO:0034796 adipate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034796 UM-BBD_reactionID:r1060 Catalysis of the reaction: adipate + CoASH = adipyl-CoA + OH-. GO:0034797 fosfomycin 2-glutathione ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034797 UM-BBD_reactionID:r1073 Catalysis of the reaction: hydrogen (2R,3S)-3-methyloxiran-2-ylphosphonic acid + glutathione = hydrogen (1R,2R)-1-glutathio-2-hydroxypropylphosphonic acid. GO:0034798 fosfomycin 2-L-cysteine ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034798 UM-BBD_reactionID:r1074 Catalysis of the reaction: hydrogen (2R,3S)-3-methyloxiran-2-ylphosphonic acid + L-cysteine = hydrogen (1R,2R)-1-L-cysteine-2-hydroxypropylphosphonic acid. GO:0034799 dihydride TNP tautomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034799 UM-BBD_reactionID:r1070 Catalysis of the reaction: TNP dihydride Meisenheimer complex (aci form) = TNP dihydride Meisenheimer complex (nitro form). GO:0019159 nicotinamide-nucleotide amidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019159 RHEA:12400|EC:3.5.1.42|MetaCyc:NMNAMIDOHYDRO-RXN NMN deamidase activity|nicotinamide mononucleotide amidohydrolase activity|NMN amidohydrolase|nicotinamide-D-ribonucleotide amidohydrolase activity|nicotinamide mononucleotide deamidase activity Catalysis of the reaction: beta-nicotinamide D-ribonucleotide + H2O = beta-nicotinate D-ribonucleotide + NH3. CHEBI:139498 N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-Asn residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139498 CHEBI:139499 N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-Asn residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139499 GO:0019157 obsolete malate oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019157 malic dehydrogenase II|malic oxidase activity|(S)-malate:oxygen oxidoreductase activity|FAD-dependent malate oxidase activity OBSOLETE. Catalysis of the reaction: (S)-malate + O(2) = H(2)O(2) + oxaloacetate. GO:0019158 mannokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019158 RHEA:11028|EC:2.7.1.7|MetaCyc:MANNKIN-RXN ATP:D-mannose 6-phosphotransferase activity|mannokinase (phosphorylating)|D-fructose (D-mannose) kinase activity Catalysis of the reaction: ATP + D-mannose = ADP + D-mannose 6-phosphate. GO:0019155 3-(imidazol-5-yl)lactate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019155 MetaCyc:IMILACTDEHYDROG-RXN|EC:1.1.1.111 imidazol-5-yl lactate dehydrogenase activity|(S)-3-(imidazol-5-yl)lactate:NAD(P)+ oxidoreductase activity Catalysis of the reaction: (S)-3-(imidazol-5-yl)lactate + NADP+ = 3-(imidazol-5-yl)pyruvate + NADPH + H+. GO:0019156 isoamylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019156 MetaCyc:RXN-12280|EC:3.2.1.68|MetaCyc:RXN-14380|MetaCyc:3.2.1.68-RXN glycogen alpha-1,6-glucanohydrolase activity|debranching enzyme activity Catalysis of the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages in glycogen, amylopectin and their beta-limits dextrins. GO:0019153 protein-disulfide reductase (glutathione) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019153 MetaCyc:PRODISULFREDUCT-RXN|EC:1.8.4.2|RHEA:21064 glutaredoxin reductase|protein-disulfide interchange enzyme|protein-disulphide reductase (glutathione) activity|thiol:protein-disulfide oxidoreductase activity|protein disulfide transhydrogenase activity|glutathione:protein-disulfide oxidoreductase activity|protein disulfide reductase (glutathione)|glutathione-insulin transhydrogenase activity|protein-disulfide isomerase/oxidoreductase activity|glutathione-protein disulfide oxidoreductase activity|insulin reductase activity|thiol-protein disulphide oxidoreductase activity|glutathione--insulin transhydrogenase activity|GSH-insulin transhydrogenase activity|reductase, protein disulfide (glutathione) Catalysis of the reaction: 2 glutathione + protein-disulfide = oxidized glutathione + protein-dithiol. GO:0034790 3,4-dihydroxy-3,4-dihydrofluorene dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034790 UM-BBD_reactionID:r1043 Catalysis of the reaction: (+)-(3S,4R)-cis-3,4-dihydroxy-3,4-dihydrofluorene = 3,4-dihydroxyfluorene + 2 H+ + 2 e-. CHEBI:139497 N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-Asn residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139497 GO:0019154 glycolate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019154 EC:1.1.99.14|MetaCyc:GLYCOLATEDEHYDRO-RXN|KEGG_REACTION:R00476|RHEA:21264 glycolic acid dehydrogenase activity|glycolate oxidoreductase activity|glycolate:acceptor 2-oxidoreductase activity|glycolate:(acceptor) 2-oxidoreductase activity Catalysis of the reaction: A + glycolate = AH(2) + glyoxylate. GO:0034791 isobutylamine N-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034791 UM-BBD_reactionID:r1053|EC:1.14.13.- Catalysis of the reaction: isobutylamine + NADPH + O2 = isobutylhydroxylamine + NADP+ + H2O. GO:0019173 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019173 GO:0019174 tetrahydrothiophene 1-oxide reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019174 MetaCyc:THTOREDUCT-RXN Catalysis of the reaction: tetrahydrothiophene 1-oxide + reduced acceptor = tetrahydrothiophene + acceptor. GO:0019171 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019171 EC:4.2.1.59|MetaCyc:3-HYDROXYDECANOYL-ACP-DEHYDR-RXN|RHEA:13097 3-hydroxyacyl-[acyl-carrier protein] dehydratase activity|3-hydroxyacyl-ACP dehydratase activity Catalysis of the reaction: a (3R)-3-hydroxyacyl-[acyl-carrier protein] = H2O + a trans-delta2-enoyl-acyl-[acyl-carrier protein]. GO:0019172 glyoxalase III activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019172 RHEA:27754|EC:4.2.1.130|MetaCyc:GLYOXIII-RXN (R)-lactate hydro-lyase|D-lactate dehydratase|glutathione-independent glyoxalase activity Catalysis of the reaction: methylglyoxal + H2O = D-lactate. CHEBI:72755 kanamycin C(4+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72755 GO:0019170 methylglyoxal reductase (NADH-dependent) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019170 EC:1.1.1.78|RHEA:24528|MetaCyc:D-LACTALDEHYDE-DEHYDROGENASE-RXN D-lactaldehyde dehydrogenase activity|methylglyoxal reductase activity|(R)-lactaldehyde:NAD+ oxidoreductase activity Catalysis of the reaction: (R)-lactaldehyde + NAD+ = methylglyoxal + NADH + H+. CHEBI:72756 kanamycin X(3+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72756 CHEBI:72757 2'-oxokanamycin(4+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72757 CHEBI:72758 sphinga-4E,8E-dienine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72758 GO:0034789 2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034789 UM-BBD_reactionID:r1042 Catalysis of the reaction: 2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate + H2O = cis-2-hydroxypenta-2,4-dienoate + phthalate + H+. GO:0034781 N-cyclohexylformamide amidohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034781 UM-BBD_reactionID:r1030 Catalysis of the reaction: N-cyclohexylformamide + OH- = cyclohexylamine + formate. GO:0034782 dimethylmalonate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034782 UM-BBD_reactionID:r1031 Catalysis of the reaction: dimethylmalonate + H+ = isobutyrate + CO2. GO:0034783 pivalate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034783 UM-BBD_reactionID:r1032 Catalysis of the reaction: pivalate + H+ + HSCoA + ATP = pivalyl-CoA + PPi + AMP. GO:0034784 pivalyl-CoA mutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034784 EC:5.4.99.-|UM-BBD_reactionID:r1033 Catalysis of the reaction: pivalyl-CoA = 3-methylbutyryl-CoA. GO:0034785 salicylate 5-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034785 MetaCyc:RXN-10446|EC:1.14.13.-|RHEA:35307|UM-BBD_reactionID:r1034 Catalysis of the reaction: salicylate + O2 + NAD(P)H + H+ = gentisate + H2O + NAD(P)+. GO:0034786 9-fluorenone-3,4-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034786 UM-BBD_reactionID:r1039 Catalysis of the reaction: 9-fluorenone + O2 + 2 H+ + 2 e- = 1-hydro-1,1a-dihydroxy-9-fluorenone. GO:0034787 1-hydro-1,1a-dihydroxy-9-fluorenone dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034787 UM-BBD_reactionID:r1040 Catalysis of the reaction: 1-hydro-1,1a-dihydroxy-9-fluorenone + H2O = 2,3-dihydroxy-2'-carboxybiphenyl + 3 H+ + 2 e-. CHEBI:140489 tropomyosin-related kinase B receptor agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_140489 GO:0034788 2,3-dihydroxy-2'-carboxybiphenyl 1,2-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034788 UM-BBD_reactionID:r1041 Catalysis of the reaction: 2,3-dihydroxy-2'-carboxybiphenyl + O2 = 2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate + H+. GO:0019168 2-octaprenylphenol hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019168 MetaCyc:2-OCTAPRENYLPHENOL-HYDROX-RXN|RHEA:27790 Catalysis of the reaction: 2-octaprenylphenol + NADPH + O2 + H+ = 2-octaprenyl-6-hydroxyphenol + NADP+ + H2O. GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019166 Reactome:R-HSA-6786720|MetaCyc:TRANSENOYLCOARED-RXN|EC:1.3.1.38|Reactome:R-HSA-6809810|Reactome:R-HSA-8952873|RHEA:33763 acyl-CoA:NADP+ trans-2-oxidoreductase activity|reductase, trans-enoyl coenzyme A|NADPH-dependent trans-2-enoyl-CoA reductase activity Catalysis of the reaction: acyl-CoA + NADP+ = trans-2,3-dehydroacyl-CoA + NADPH + H+. GO:0019167 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019167 GO:0019164 pyruvate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019164 MetaCyc:PYRUFLAVREDUCT-RXN|KEGG_REACTION:R01196|EC:1.2.7.1|RHEA:12765 pyruvate:ferredoxin oxidoreductase activity|pyruvate-ferredoxin reductase activity|PFOR|pyruvic-ferredoxin oxidoreductase activity|pyruvate synthetase activity|pyruvate:ferredoxin 2-oxidoreductase (CoA-acetylating)|pyruvate oxidoreductase activity Catalysis of the reaction: pyruvate + CoA + 2 oxidized ferredoxin = acetyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+. GO:0019165 thiamine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019165 RHEA:12012|MetaCyc:THIKIN-RXN|EC:2.7.1.89|KEGG_REACTION:R02134 ATP:thiamin phosphotransferase activity|thiamin phosphokinase activity|thiamin kinase (phosphorylating)|ATP:thiamine phosphotransferase activity|thiamin kinase activity Catalysis of the reaction: ATP + thiamine = ADP + 2 H(+) + thiamine phosphate. GO:0034780 glyphosate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034780 UM-BBD_reactionID:r0073 Catalysis of the reaction: glyphosate + OH- = glyoxylate + aminomethylphosphonic acid + H+ + 2 e-. CHEBI:72750 neosartoricin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72750 GO:0019140 inositol 3-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019140 EC:2.7.1.64|MetaCyc:MYO-INOSITOL-1-KINASE-RXN|RHEA:21804 inositol-1-kinase (phosphorylating)|inositol 1-kinase activity|ATP:myo-inositol 1-phosphotransferase activity|myoinositol kinase activity|myo-inositol 1-kinase activity|myo-inositol 3-kinase activity Catalysis of the reaction: ATP + myo-inositol = ADP + 1D-myo-inositol 3-phosphate. CHEBI:72762 6-hydroxytryprostatin B biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72762 GO:0019141 2-dehydropantolactone reductase (B-specific) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019141 EC:1.1.1.214|MetaCyc:DEHYDROPANTLACRED-RXN (R)-pantolactone:NADP+ oxidoreductase (B-specific)|2-oxopantoyl lactone reductase|ketopantoyl lactone reductase activity|2-ketopantoyl lactone reductase activity|2-dehydropantoyl-lactone reductase (B-specific) activity Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+. The reaction is B-specific (i.e. the pro-S hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NADP+. CHEBI:139480 (+)-O-methylkolavelool biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139480 CHEBI:72763 fumitremorgin C biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72763 CHEBI:72764 12,13-dihydroxyfumitremorgin C biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72764 CHEBI:139481 5-chloro-L-tryptophan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139481 CHEBI:72765 verruculogen biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72765 CHEBI:72766 fumitremorgin A biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72766 CHEBI:72767 demethoxyfumitremorgin C biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72767 CHEBI:72768 aryl hydrocarbon receptor agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72768 CHEBI:72769 2'-oxokanamycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72769 GO:0034778 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034778 UM-BBD_reactionID:r1003 Catalysis of the reaction: 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA = 4-isopropenyl-2-ketocyclohexane-1-carboxyl-CoA + 2 H+ + 2 e-. GO:0034779 4-isopropenyl-2-ketocyclohexane-1-carboxyl-CoA hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034779 UM-BBD_reactionID:r1004 Catalysis of the reaction: 4-isopropenyl-2-ketocyclohexane-1-carboxyl-CoA + H2O = 3-isopropenylpimelyl-CoA. CHEBI:140471 triricinolein biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140471 GO:0034770 histone H4-K20 methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034770 histone lysine H4 K20 methylation|histone H4 K20 methylation|histone H4K20me The modification of histone H4 by addition of one or more methyl groups to lysine at position 20 of the histone. GO:0034771 histone H4-K20 monomethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034771 histone lysine H4 K20 monomethylation|histone H4 K20 monomethylation The modification of histone H4 by addition of one methyl group to lysine at position 20 of the histone. GO:0034772 histone H4-K20 dimethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034772 histone lysine H4 K20 dimethylation|histone H4 K20 dimethylation The modification of histone H4 by addition of two methyl groups to lysine at position 20 of the histone. GO:0034773 histone H4-K20 trimethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034773 histone lysine H4 K20 trimethylation|histone H4 K20 trimethylation The modification of histone H4 by addition of three methyl groups to lysine at position 20 of the histone. GO:0034774 secretory granule lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034774 The volume enclosed by the membrane of a secretory granule. GO:0034775 glutathione transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034775 glutathione membrane transport|transmembrane glutathione transport A process in which glutathione is transported across a membrane. GO:0019139 cytokinin dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019139 EC:1.5.99.12|MetaCyc:PWY-2841|RHEA:13625|MetaCyc:1.5.99.12-RXN 6-N-dimethylallyladenine:acceptor oxidoreductase activity|cytokinin oxidase activity|N6-dimethylallyladenine:(acceptor) oxidoreductase activity|N6-dimethylallyladenine:acceptor oxidoreductase activity Catalysis of the reaction: N6-dimethylallyladenine + acceptor + H2O = adenine + 3-methylbut-2-enal + reduced electron acceptor. GO:0034776 response to histamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034776 response to histamine stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter. GO:0034777 recycling endosome lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034777 The volume enclosed by the membranes of a recycling endosome. GO:0019137 thioglucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019137 MetaCyc:RXN-9946|EC:3.2.1.147 sinigrinase activity|sinigrase activity|thioglucoside glucohydrolase activity|myrosinase activity Catalysis of the reaction: a thioglucoside + H2O = a thiol + a sugar. GO:0019138 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019138 CHEBI:139477 mogroside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139477 GO:0019135 deoxyhypusine monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019135 MetaCyc:DEOXYHYPUSINE-MONOOXYGENASE-RXN|Reactome:R-HSA-204662|RHEA:14101|EC:1.14.99.29 deoxyhypusine dioxygenase activity|deoxyhypusine,hydrogen-donor:oxygen oxidoreductase (2-hydroxylating)|DOHH activity|deoxyhypusine hydroxylase activity Catalysis of the reaction: protein N6-(4-aminobutyl)-L-lysine + donor-H2 + O2 = protein N6-((R)-4-amino-2-hydroxybutyl)-L-lysine + acceptor + H2O. CHEBI:139478 nerylneryl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139478 GO:0019136 deoxynucleoside kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019136 MetaCyc:2.7.1.145-RXN|EC:2.7.1.145|RHEA:12140 ms-dNK|D. melanogaster deoxynucleoside kinase activity|multisubstrate deoxyribonucleoside kinase activity|multispecific deoxynucleoside kinase activity|Ms-dNK activity|multifunctional deoxynucleoside kinase activity|ATP:deoxynucleoside 5'-phosphotransferase activity|Dm-dNK Catalysis of the reaction: ATP + 2'-deoxynucleoside = ADP + 2'-deoxynucleoside 5'-phosphate. CHEBI:139479 norbaeocystin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139479 CHEBI:139472 (4S)-2,3-dehydroleucopelargonidin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139472 GO:0019133 choline monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019133 MetaCyc:RXN1F-357|RHEA:17769|EC:1.14.15.7 choline,reduced-ferredoxin:oxygen oxidoreductase activity Catalysis of the reaction: choline + 2 reduced ferredoxin + O2 + 2 H+ = betaine aldehyde hydrate + 2 oxidized ferredoxin + H2O. GO:0019134 glucosamine-1-phosphate N-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019134 RHEA:13725|MetaCyc:2.3.1.157-RXN|KEGG_REACTION:R05332|EC:2.3.1.157 acetyl-CoA:D-glucosamine-1-phosphate N-acetyltransferase activity|acetyl-CoA:alpha-D-glucosamine-1-phosphate N-acetyltransferase activity Catalysis of the reaction: alpha-D-glucosamine 1-phosphate + acetyl-CoA = N-acetyl-alpha-D-glucosamine 1-phosphate + CoA + H(+). CHEBI:72760 tryprostatin B biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72760 GO:0019131 obsolete tripeptidyl-peptidase I activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019131 tripeptidyl aminopeptidase activity|tripeptidyl peptidase activity|tripeptidyl-peptidase I activity OBSOLETE. Catalysis of the release of an N-terminal tripeptide from a polypeptide; requires acid pH. GO:0019132 obsolete C-terminal processing peptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019132 protease Re|CtpA gene product (Synechocystis sp.)|Tsp protease|photosystem II D1 protein processing peptidase|tail-specific protease activity|C-terminal processing peptidase activity OBSOLETE. Catalysis of the cleavage of peptides after specific recognition of a C-terminal tripeptide, Xaa-Yaa-Zaa, in which Xaa is preferably Ala or Leu, Yaa is preferably Ala or Tyr, and Zaa is preferably Ala. Cleavage is at a variable distance from the C-terminus; a typical cleavage is -Ala-Ala-Arg-Ala-Ala-Lys-Glu-Asn-Tyr-Ala-Leu-Ala-Ala. CHEBI:72761 tryprostatin A biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72761 GO:0019151 galactose 1-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019151 EC:1.1.1.48|MetaCyc:GALACTODEHYDROG-RXN|RHEA:21296 D-galactose dehydrogenase activity|NAD-dependent D-galactose dehydrogenase activity|D-galactose:NAD+ 1-oxidoreductase activity|beta-galactose dehydrogenase activity|D-galactose 1-dehydrogenase activity Catalysis of the reaction: D-galactose + NAD+ = D-galactono-1,4-lactone + NADH + H+. GO:0019152 acetoin dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019152 KEGG_REACTION:R02343|MetaCyc:ACETOINDEHYDROG-RXN|EC:1.1.1.304|EC:1.1.1.303 diacetyl reductase activity Catalysis of the reaction: acetoin + NAD+ = diacetyl + NADH + H+. CHEBI:72775 methyl benzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72775 CHEBI:139492 sensitiser biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139492 GO:0019150 D-ribulokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019150 EC:2.7.1.47|RHEA:17601|MetaCyc:D-RIBULOKIN-RXN ATP:D-ribulose 5-phosphotransferase activity|D-ribulokinase (phosphorylating) Catalysis of the reaction: ATP + D-ribulose = ADP + D-ribulose 5-phosphate. CHEBI:72776 kunzeaol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72776 CHEBI:139493 N(4)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc]-L-Asn residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139493 CHEBI:72777 7,8-dihydroneopterin 2'-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72777 CHEBI:72778 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72778 GO:0034767 positive regulation of ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034767 up-regulation of transmembrane ion transport|upregulation of transmembrane ion transport|up regulation of transmembrane ion transport|activation of transmembrane ion transport|positive regulation of transmembrane ion transport|stimulation of transmembrane ion transport|positive regulation of ion membrane transport Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other. GO:0034768 (E)-beta-ocimene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034768 EC:4.2.3.106|RHEA:32691|MetaCyc:RXN-5109 Catalysis of the reaction: geranyl diphosphate = (E)-beta-ocimene + diphosphate. CHEBI:140466 hederagenin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140466 GO:0034769 basement membrane disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034769 basal lamina disassembly The controlled breakdown of the basement membrane in the context of a normal process such as imaginal disc eversion. GO:0034760 negative regulation of iron ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034760 negative regulation of transmembrane iron ion transport|down-regulation of transmembrane iron ion transport|negative regulation of transmembrane iron transport|downregulation of transmembrane iron ion transport|down regulation of transmembrane iron ion transport|negative regulation of iron ion membrane transport|inhibition of transmembrane iron ion transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore. GO:0034761 positive regulation of iron ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034761 stimulation of transmembrane iron ion transport|positive regulation of transmembrane iron ion transport|up-regulation of transmembrane iron ion transport|activation of transmembrane iron ion transport|up regulation of transmembrane iron ion transport|positive regulation of iron ion membrane transport|positive regulation of transmembrane iron transport|upregulation of transmembrane iron ion transport Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore. GO:0034762 regulation of transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034762 regulation of membrane transport Any process that modulates the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other. GO:0034763 negative regulation of transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034763 down-regulation of transmembrane transport|inhibition of transmembrane transport|negative regulation of membrane transport|down regulation of transmembrane transport|downregulation of transmembrane transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other. GO:0034764 positive regulation of transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034764 activation of transmembrane transport|stimulation of transmembrane transport|up-regulation of transmembrane transport|upregulation of transmembrane transport|positive regulation of membrane transport|up regulation of transmembrane transport Any process that activates or increases the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other. GO:0034765 regulation of ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034765 regulation of ion membrane transport|regulation of transmembrane ion transport Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other. CHEBI:140467 gypsogenin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140467 GO:0034766 negative regulation of ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034766 inhibition of transmembrane ion transport|down regulation of transmembrane ion transport|negative regulation of transmembrane ion transport|downregulation of transmembrane ion transport|negative regulation of ion membrane transport|down-regulation of transmembrane ion transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other. CHEBI:140468 gypsogenate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140468 GO:0019148 D-cysteine desulfhydrase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019148 RHEA:11268|MetaCyc:DCYSDESULF-RXN|EC:4.4.1.15 D-cysteine lyase activity|D-cysteine sulfide-lyase (deaminating; pyruvate-forming)|D-cysteine sulfide-lyase (deaminating) Catalysis of the reaction: D-cysteine + H2O = sulfide + NH3 + pyruvate. GO:0019149 3-chloro-D-alanine dehydrochlorinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019149 EC:4.5.1.2|RHEA:18873|MetaCyc:3-CHLORO-D-ALANINE-DEHYDROCHLORINASE-RXN beta-chloro-D-alanine dehydrochlorinase activity|3-chloro-D-alanine chloride-lyase (deaminating; pyruvate-forming)|3-chloro-D-alanine chloride-lyase (deaminating) Catalysis of the reaction: 3-chloro-D-alanine + H2O = pyruvate + chloride + NH3. GO:0019146 arabinose-5-phosphate isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019146 RHEA:23104|KEGG_REACTION:R01530|MetaCyc:DARAB5PISOM-RXN|EC:5.3.1.13 phosphoarabinoisomerase activity|D-arabinose-5-phosphate ketol-isomerase activity|arabinose phosphate isomerase activity|D-arabinose-5-phosphate aldose-ketose-isomerase activity Catalysis of the reaction: D-arabinose 5-phosphate = D-ribulose 5-phosphate + 2 H(+). GO:0019147 (R)-aminopropanol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019147 RHEA:16517|MetaCyc:AMINOPROPDEHYDROG-RXN|KEGG_REACTION:R03759|EC:1.1.1.75 (R)-1-aminopropan-2-ol:NAD+ oxidoreductase activity|L(+)-1-aminopropan-2-ol:NAD+ oxidoreductase activity|1-aminopropan-2-ol-NAD+ dehydrogenase activity|DL-1-aminopropan-2-ol: NAD+ dehydrogenase activity|L(+)-1-aminopropan-2-ol-NAD/NADP oxidoreductase activity|1-aminopropan-2-ol-dehydrogenase activity|L-aminopropanol dehydrogenase activity Catalysis of the reaction: (R)-1-aminopropan-2-ol + NAD(+) = aminoacetone + H(+) + NADH. GO:0019144 ADP-sugar diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019144 EC:3.6.1.21|MetaCyc:ADPSUGPPHOSPHAT-RXN nucleoside diphosphate-sugar hydrolase activity|ADP-sugar sugarphosphohydrolase activity|ADPsugar pyrophosphatase activity|adenosine diphosphosugar pyrophosphatase activity|ADP-sugar pyrophosphatase activity Catalysis of the reaction: ADP-sugar + H2O = AMP + sugar 1-phosphate. GO:0019145 aminobutyraldehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019145 MetaCyc:AMINOBUTDEHYDROG-RXN|RHEA:19105|EC:1.2.1.19 ABAL dehydrogenase activity|4-aminobutyraldehyde dehydrogenase activity|4-aminobutanal dehydrogenase activity|gamma-aminobutyraldehyde dehydroganase activity|4-aminobutanal:NAD+ 1-oxidoreductase activity Catalysis of the reaction: 4-aminobutanal + NAD+ + H2O = 4-aminobutanoate + NADH + 2 H+. GO:0019142 2-hydroxyglutarate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019142 MetaCyc:HYDGLUTSYN-RXN|RHEA:19185|KEGG_REACTION:R00932|EC:2.3.3.11 propanoyl-CoA:glyoxylate C-propanoyltransferase (thioester-hydrolysing, 2-carboxyethyl-forming)|2-hydroxyglutaric synthetase activity|hydroxyglutarate synthase activity|2-hydroxyglutaratic synthetase activity|2-hydroxyglutarate glyoxylate-lyase (CoA-propanoylating) activity|alpha-hydroxyglutarate synthase activity Catalysis of the reaction: glyoxylate + H(2)O + propanoyl-CoA = 2-hydroxyglutarate + CoA + H(+). CHEBI:72771 breast cancer resistance protein inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72771 GO:0019143 3-deoxy-manno-octulosonate-8-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019143 KEGG_REACTION:R03350|MetaCyc:KDO-8PPHOSPHAT-RXN|EC:3.1.3.45|RHEA:11500 3-deoxy-D-manno-octulosonate-8-phosphate 8-phosphohydrolase activity Catalysis of the reaction: 8-phospho-3-deoxy-D-manno-oct-2-ulosonate + H(2)O = 3-deoxy-D-manno-octulosonate + phosphate. CHEBI:72772 beta-leucine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72772 CHEBI:72784 7,8-dihydroneopterin 2'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72784 CHEBI:72787 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72787 CHEBI:72788 7,8-dihydromethanopterin(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72788 GO:0034756 regulation of iron ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034756 regulation of Fe transport|regulation of iron ion import|regulation of iron transport|regulation of iron import Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:140454 O-[S-(5-bromopyrrole-2-carbonyl)pantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140454 GO:0010789 meiotic sister chromatid cohesion involved in meiosis I biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010789 The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis I. GO:0034757 negative regulation of iron ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034757 down-regulation of iron ion transport|negative regulation of iron transport|downregulation of iron ion transport|down regulation of iron ion transport|inhibition of iron ion transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:140455 O-[S-(4,5-dibromopyrrole-2-carbonyl)pantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140455 GO:0034758 positive regulation of iron ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034758 up-regulation of iron ion transport|activation of iron ion transport|up regulation of iron ion transport|positive regulation of iron transport|upregulation of iron ion transport|stimulation of iron ion transport Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0010787 COPI coating of Golgi vesicle, inter-Golgi cisterna biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010787 The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of inter-Golgi cisterna transport vesicles, forming a vesicle coat. CHEBI:140452 1-[(1Z)-octadecenyl]-2-oleoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140452 GO:0034759 regulation of iron ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034759 regulation of transmembrane iron ion transport|regulation of iron ion membrane transport|regulation of transmembrane iron transport|regulation of transmembrane Fe transport Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) from one side of a membrane to the other by means of some agent such as a transporter or pore. GO:0010788 COPI coating of Golgi vesicle, cis-Golgi to rough ER biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010788 The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of cis-Golgi to rough ER transport vesicles, forming a vesicle coat. CHEBI:140451 N-acyl-1-[(1Z)-alkenyl]-2-acyl-sn-glycero-3-phosphoethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140451 GO:0009792 embryo development ending in birth or egg hatching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009792 embryogenesis The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell. GO:0010781 meiotic DNA double-strand break formation involved in meiotic gene conversion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010781 The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another. GO:0009793 embryo development ending in seed dormancy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009793 embryogenesis The process whose specific outcome is the progression of the embryo over time, from zygote formation to the end of seed dormancy. An example of this process is found in Arabidopsis thaliana. GO:0010782 proboscis morphogenesis, labial disc-derived biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010782 The process in which the anatomical structures of the proboscis that are derived from the labial disc are generated and organized. GO:0009794 regulation of mitotic cell cycle, embryonic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009794 regulation of progression through embryonic mitotic cell cycle|embryonic mitotic cell cycle modulation|regulation of embryonic mitotic cell cycle progression|modulation of embryonic mitotic cell cycle progression|regulation of embryonic mitotic cell cycle|embryonic mitotic cell cycle regulation|embryonic mitotic cell cycle regulator Any process that modulates the frequency, rate or extent of replication and segregation of genetic material in the embryo. GO:0034750 Scrib-APC-beta-catenin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034750 hScrib-APC-beta-catenin complex A protein complex that contains the Scribble protein (a cell polarity determinant), the tumor suppressor protein adenomatous polyposis coli (APC), and beta-catenin; may be involved in the control of cell proliferation. GO:0034751 aryl hydrocarbon receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034751 AhR complex|AHRC A protein complex that acts as an aryl hydrocarbon (Ah) receptor. Cytosolic and nuclear Ah receptor complexes have different subunit composition, but both contain the ligand-binding subunit AhR. GO:0009795 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009795 GO:0010780 meiotic DNA double-strand break formation involved in reciprocal meiotic recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010780 The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate. GO:0019119 phenanthrene-9,10-epoxide hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019119 Catalysis of the reaction: phenanthrene-9,10-oxide + H2O = trans-9,10-dihydrodiolphenanthrene. GO:0034752 cytosolic aryl hydrocarbon receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034752 cytosolic AhR complex|9S-cytosolic aryl hydrocarbon (Ah) receptor non-ligand activated complex|cytosolic AHRC An aryl hydrocarbon receptor complex found in the cytosol, in which the ligand-binding subunit AhR is not bound to ligand; consists of AhR, two molecules of HSP90, the protein kinase c-Src, and the immunophilin XAP2/AIP. GO:0009796 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009796 GO:0010785 clathrin coating of Golgi vesicle, plasma membrane to endosome targeting biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010785 The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles that will move from the plasma membrane to the endosome, forming a vesicle coat. GO:0009797 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009797 GO:0010786 clathrin coating of Golgi vesicle, trans-Golgi to endosome targeting biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010786 The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles that will move from the trans-Golgi to the endosome, forming a vesicle coat. GO:0034753 nuclear aryl hydrocarbon receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034753 nuclear AHRC|6S-nuclear aryl hydrocarbon (Ah) receptor ligand-activated complex|nuclear AhR complex An aryl hydrocarbon receptor (AhR) complex found in the nucleus; ; consists of ligand-bound AhR and the aryl hydrocarbon receptor nuclear translocator (ARNT). GO:0009798 axis specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009798 axis determination The establishment, maintenance and elaboration of a pattern along a line or around a point. GO:0010783 proboscis morphogenesis, eye-antennal disc-derived biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010783 The process in which the anatomical structures of the proboscis that are derived from the eye-antennal disc are generated and organized. CHEBI:140456 O-[S-(3,4,5-tribromopyrrole-2-carbonyl)pantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140456 GO:0034754 cellular hormone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034754 The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone, as carried out by individual cells. GO:0019117 dihydroxyfluorene dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019117 EC:1.13.11.- Catalysis of the reaction: a dihydroxyfluorene + O2 = the corresponding 2-hydroxy-4-(oxo-1,3-dihydro-2H-inden-ylidene) but-2-enoic acid. GO:0019118 phenanthrene-epoxide hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019118 EC:3.3.2.- Catalysis of the reaction: a phenanthrene dioxide + H2O = a dihydrodiolphenanthrene. GO:0034755 iron ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034755 iron(2+) transmembrane transport|high affinity iron ion transport|low-affinity iron ion transmembrane transport|transmembrane iron transport|high-affinity ferrous ion transmembrane transport|high-affinity iron ion transport|iron ion membrane transport|low affinity iron ion transport|high-affinity iron ion transmembrane transport|high affinity ferrous ion transmembrane transport|ferrous iron transmembrane transport|ferrous ion transmembrane transport|low-affinity iron ion transport A process in which an iron ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. GO:0009799 specification of symmetry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009799 determination of symmetry The establishment of an organism's body plan or part of an organism such that a similar arrangement in form and relationship of parts around a common axis, or around each side of a plane is created. GO:0010784 proboscis morphogenesis, clypeo-labral disc-derived biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010784 The process in which the anatomical structures of the proboscis that are derived from the clypeo-labral disc are generated and organized. GO:0019115 benzaldehyde dehydrogenase [NAD(P)+] activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019115 EC:1.2.1.- Catalysis of the reaction: benzaldehyde + NAD(P)+ + H2O = benzoate + NAD(P)H + H+. GO:0019116 hydroxy-nicotine oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019116 EC:1.5.3.6 Catalysis of the reaction: 6-hydroxynicotine + H2O + O2 = 1-(6-hydroxypyrid-3-yl)-4-(methylamino)butan-1-one + hydrogen peroxide. GO:0019113 limonene monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019113 EC:1.14.13.- Catalysis of a monooxygenase reaction in which oxygen is incorporated into limonene. GO:0019114 catechol dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019114 EC:1.13.11.- Catalysis of the reaction: catechol + O2 = a muconate. CHEBI:72780 cobalt-precorrin-6B(7-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72780 GO:0019111 phenanthrol sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019111 phenanthrol sulphotransferase activity Catalysis of the reaction: phenanthrol + X-SO3(-) = HX + phenanthrylsulfate. GO:0019112 phenanthrol glycosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019112 Catalysis of the reaction: phenanthrol + glucose = phenanthryl-beta-D-glucopyranoside + H2O. CHEBI:72781 6-tuliposide A biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72781 CHEBI:72782 methyl (indol-3-yl)acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72782 GO:0019110 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019110 CHEBI:72783 12-HHTrE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72783 GO:0019130 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019130 CHEBI:72797 kanamycin X biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72797 CHEBI:139471 (4S)-2,3-dehydroleucocyanidin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139471 CHEBI:72799 HEPE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72799 GO:0034745 APC-IQGAP1-Rac1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034745 A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), the small GTPase Rac1, and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization and cell migration. GO:0034746 APC-IQGAP1-CLIP-170 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034746 A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), the small GTPase Cdc42, and CLIP-170; may play a role in cytoskeleton organization and cell migration. CHEBI:140444 linoleoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140444 GO:0034747 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0034747 GO:0010798 regulation of multivesicular body size involved in ubiquitin-dependent protein catabolism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010798 Any process that modulates the volume of a multivesicular body as part of the chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin. CHEBI:140441 12-epi-hapalindole U biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140441 GO:0034748 Par3-APC-KIF3A complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034748 A protein complex that contains Par3, the tumor suppressor protein adenomatous polyposis coli (APC), and the kinesin-related protein KIF3A; involved in establishing neuronal cell polarity. GO:0010799 regulation of peptidyl-threonine phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010799 Any process that modulates the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine. CHEBI:140442 12-epi-fischerindole U biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140442 GO:0034749 Scrib-APC complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034749 hScrib-APC complex A protein complex that contains the Scribble protein (a cell polarity determinant) and the tumor suppressor protein adenomatous polyposis coli (APC); may be involved in the control of cell proliferation. CHEBI:140440 hapalindole H biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140440 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010792 The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang that results in the repair of a double strand break via single-strand annealing. GO:0010793 regulation of mRNA export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010793 Any process that modulates the frequency, rate or extent of the directed movement of mRNA from the nucleus to the cytoplasm. GO:0010790 meiotic sister chromatid cohesion involved in meiosis II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010790 The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis II. GO:0010791 DNA double-strand break processing involved in repair via synthesis-dependent strand annealing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010791 The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang that results in the repair of a double strand break via synthesis-dependent strand annealing. GO:0034740 TFIIIC-TOP1-SUB1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034740 TFIIIC-Topoisomerase 1-PC4 complex A protein complex that contains TFIIIC, topoisomerase 1, and Sub1/PC4. Characterized in human, the complex is involved in regulating transcription from RNA polymerase III (Pol III) promoters. Topoisomerase 1 and Sub1 enhance the accuracy of transcription termination, and promote reinitiation by Pol III. GO:0010796 regulation of multivesicular body size biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010796 Any process that modulates the volume of a multivesicular body, a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles. GO:0034741 APC-tubulin-IQGAP1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034741 60S APC complex A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), alpha-tubulin, gamma-tubulin, and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization. GO:0034742 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0034742 GO:0010797 regulation of multivesicular body size involved in endosome transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010797 Any process that modulates the volume of a multivesicular body as part of the directed movement of substances from endosomes to lysosomes or vacuoles. CHEBI:140445 alpha-linolenoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140445 GO:0019128 peptidyl-tryptophan racemization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019128 RESID:AA0198 The racemization of peptidyl-tryptophan. GO:0034743 APC-IQGAP complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034743 A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC) and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization and cell migration. GO:0010794 regulation of dolichol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010794 Any process that modulates the frequency, rate or extent of dolichol biosynthesis. Dolichol biosynthesis consists of the chemical reactions and pathways resulting in the formation of dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units. GO:0010795 regulation of ubiquinone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010795 Any process that modulates the frequency, rate or extent of ubiquinone biosynthesis. Ubiquinone biosynthesis consists of the chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme. GO:0019129 peptidyl-leucine racemization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019129 RESID:AA0197 The racemization of peptidyl-leucine. GO:0034744 APC-IQGAP1-Cdc42 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034744 A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), the small GTPase Cdc42, and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization and cell migration. CHEBI:140446 ricinoleoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140446 GO:0019126 peptidyl-serine racemization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019126 RESID:AA0195 The racemization of peptidyl-serine. GO:0019127 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019127 GO:0019124 peptidyl-isoleucine racemization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019124 RESID:AA0192 The racemization of peptidyl-isoleucine. GO:0019125 peptidyl-phenylalanine racemization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019125 RESID:AA0194 The racemization of peptidyl-phenylalanine. CHEBI:72790 hydroxydocosahexaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72790 GO:0019122 peptidyl-D-alanine racemization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019122 RESID:AA0191 alanine racemization The formation of peptidyl-D-alanine, by either racemization or from peptidyl-L-serine. GO:0019123 peptidyl-methionine racemization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019123 RESID:AA0193 The racemization of peptidyl-methionine. GO:0019120 hydrolase activity, acting on acid halide bonds, in C-halide compounds biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019120 EC:3.8.1.-|Reactome:R-HSA-9011595 Catalysis of the hydrolysis of any acid halide bond in substances containing halogen atoms in organic linkage. CHEBI:72793 HETrE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72793 GO:0019121 peptidoglycan-protein cross-linking via N6-mureinyl-L-lysine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019121 RESID:AA0218 The process of linking a protein to peptidoglycan via the epsilon amino group of lysine to the diaminopimelic acid of the peptidoglycan. CHEBI:23711 diethyl 2-methyl-3-hydroxysuccinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_23711 UBERON:0014393 sweat of axilla biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014393 axillary sweat Sweat that is produced by the glands of the axilla. UBERON:0014394 uterine fat pad biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014394 periuterine fat pad|uterine fat depot|peri-uterine fat pad Encapsulated adipose tissue associated with the uterus UBERON:0014395 proximal mesopodial bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014395 A proximal mesopodial endochondral element that is composed primarily of a bone tissue. CHEBI:23700 dichlorohydroquinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23700 UBERON:0014398 respiratory muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014398 Muscle that is part of the respiratory system. UBERON:0014399 sinusoidal space biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014399 lumen of sinusoid|sinusoid lumen A anatomical space that is enclosed by a sinusoid. CHEBI:23702 dichlorophenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23702 CHEBI:23703 dideoxyhexose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23703 GO:0019098 reproductive behavior biolink:BiologicalProcess go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0019098 reproductive behavior in a multicellular organism|reproductive behaviour|multicellular organism reproductive behavior|single-organism reproductive behavior The specific behavior of an organism that is associated with reproduction. GO:0019099 female germ-line sex determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019099 sex determination, female germ-line determination The determination of sex and sexual phenotype in a female organism's germ line. GO:0019085 early viral transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019085 immediate early viral mRNA transcription The first phase of viral transcription that occurs after entry of the virus into the host cell, but prior to viral genome replication. It involves the transcription of genes for non-structural proteins, and for lytic viruses, the early gene products are involved in establishing control over the host cell. GO:0019086 late viral transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019086 late viral mRNA transcription The transcription of the final group of viral genes of the viral life cycle, following middle transcription, or where middle transcription doesn't occur, following early transcription. Involves the transcription of genes encoding structural proteins. GO:0019083 viral transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019083 The process by which a viral genome, or part of a viral genome, is transcribed within the host cell. GO:0019084 middle viral transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019084 (delayed) early viral mRNA transcription The viral transcription that takes place after early transcription in the viral life cycle, and which involves the transcription of genes required for replication. GO:0019081 viral translation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019081 viral protein biosynthetic process|viral protein anabolism|viral protein synthesis|viral protein biosynthesis|viral protein formation A process by which viral mRNA is translated into viral protein, using the host cellular machinery. CHEBI:72700 2-oxopimelic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72700 GO:0019082 viral protein processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019082 Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a viral protein. CHEBI:72701 2-oxopimelate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72701 GO:0019080 viral gene expression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019080 viral genome expression A process by which a viral gene is converted into a mature gene product or products (proteins or RNA). This includes viral transcription, processing to produce a mature RNA product, and viral translation. CHEBI:72704 chromenyliums biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72704 CHEBI:72705 cyanidin 3-O-[6-O-(4-O-beta-D-glucosyl-p-coumaroyl)-2-O-(beta-D-xylosyl)-beta-D-glucosyl]-5-O-(6-O-malonyl-beta-D-glucoside) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72705 CHEBI:72707 (2S)-versicolorone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72707 GO:0019078 obsolete lytic viral budding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019078 lytic viral budding OBSOLETE. A form of viral release in which the viral particles bud out through cellular membranes, resulting in cell lysis. It is also a form of viral envelopment. GO:0019079 viral genome replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019079 sigma virus replication|viral replication Any process involved directly in viral genome replication, including viral nucleotide metabolism. GO:0019076 viral release from host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019076 VZ:1076 virus exit from host cell|viral exit|viral release|release of virus from host|viral shedding The dissemination of mature viral particles from the host cell, e.g. by cell lysis or the budding of virus particles from the cell membrane. GO:0019077 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019077 GO:0019096 pole plasm mitochondrial lrRNA localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019096 oocyte pole plasm mitochondrial lrRNA localization|pole plasm mitochondrial lrRNA localisation|establishment and maintenance of mitochondrial lrRNA localization in pole plasm Any process in which mitochondrial large ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster. GO:0019097 pole plasm mitochondrial srRNA localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019097 oocyte pole plasm mitochondrial srRNA localization|pole plasm mitochondrial srRNA localisation|establishment and maintenance of mitochondrial localization in pole plasm Any process in which mitochondrial small ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster. GO:0019094 pole plasm mRNA localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019094 pole plasm mRNA localisation|pole granule RNA localization|oocyte pole plasm mRNA localization|establishment and maintenance of mRNA localization in pole plasm|establishment and maintenance of pole plasm mRNA localization Any process in which mRNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster. GO:0019095 pole plasm mitochondrial rRNA localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019095 establishment and maintenance of mitochondrial rRNA localization in pole plasm|pole plasm mitochondrial rRNA localisation|oocyte pole plasm mitochondrial rRNA localization Any process in which mitochondrial ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster. GO:0019092 mitochondrial srRNA export from mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019092 mitochondrial srRNA export from mitochondria|mitochondrial srRNA transport from mitochondrion|mitochondrial srRNA, mitochondrial export|export of mitochondrial srRNA|mitochondrial srRNA export out of mitochondrion|mitochondrial srRNA export The process in which a srRNA, small subunit ribosomal ribonucleic acid, is transported from the mitochondrial matrix into the cytosol. GO:0019093 mitochondrial RNA localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019093 mtRNA localization|establishment and maintenance of mitochondrial RNA localization|mitochondrial RNA localisation Any process in which mitochondrial RNA is transported to, or maintained in, a specific location. GO:0019090 mitochondrial rRNA export from mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019090 mitochondrial rRNA export out of mitochondrion|export of mitochondrial rRNA|mitochondrial rRNA transport from mitochondrion|mitochondrial rRNA export|mitochondrial rRNA, mitochondrial export|mitochondrial rRNA export from mitochondria The process in which a rRNA, ribosomal ribonucleic acid, is transported from the mitochondrial matrix into the cytosol. GO:0019091 mitochondrial lrRNA export from mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019091 mitochondrial lrRNA export out of mitochondrion|mitochondrial lrRNA transport from mitochondrion|mitochondrial lrRNA export|mitochondrial lrRNA, mitochondrial export|export of mitochondrial lrRNA|mitochondrial lrRNA export from mitochondria The process in which a lrRNA, large subunit ribosomal ribonucleic acid, is transported from the mitochondrial matrix into the cytosol. CHEBI:72714 tetracosahexaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72714 CHEBI:72718 N-dodecanoylsphingosine 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72718 GO:0019089 obsolete transmission of virus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019089 viral transmission OBSOLETE. The transfer of virions in order to create new infection. GO:0019087 transformation of host cell by virus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019087 Wikipedia:Viral_transformation viral transformation of host cell|host cell transformation|immortalization of host cell by virus|host cell immortalization|transformation of host cell|immortalization of host cell|viral transformation|viral immortalization A virus-induced cellular transformation resulting in immortalized cells, or cells capable of indefinite replication. GO:0019088 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019088 CHEBI:47762 phosphoethanolamine-Kdo2-lipid A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47762 CHEBI:47763 beta-L-Ara4N-lipid A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47763 GO:0044020 histone methyltransferase activity (H4-R3 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044020 histone-arginine N-methyltransferase activity (H4-R3 specific)|histone methylase activity (H4-R3 specific) Catalysis of the reaction: S-adenosyl-L-methionine + (histone H4)-arginine (position 3) = S-adenosyl-L-homocysteine + (histone H4)-N-methyl-arginine (position 3). This reaction is the addition of a methyl group to arginine at position 3 of histone H4. CHEBI:23796 diiodotyrosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23796 CHEBI:23793 dihydroxypyridine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23793 CHEBI:23798 dimethoxyflavone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23798 GO:0044027 hypermethylation of CpG island biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044027 DNA hypermethylation of CpG island An increase in the epigenetic methylation of cytosine and adenosine residues in a CpG island in DNA. CpG islands are genomic regions that contain a high frequency of the CG dinucleotide and are often associated with the transcription start site of genes. CHEBI:33118 boric acid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33118 GO:0044028 DNA hypomethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044028 An decrease in the epigenetic methylation of cytosine and adenosine residues in DNA. GO:0044025 histone kinase activity (H2B-S14 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044025 histone-serine kinase activity (H2B-S14 specific)|histone serine kinase activity (H2B-S14 specific) Catalysis of the transfer of a phosphate group to the serine-14 or an equivalent residue of the N-terminal tail of histone H2B. GO:0044026 DNA hypermethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044026 An increase in the epigenetic methylation of cytosine and adenosine residues in DNA. GO:0044023 histone kinase activity (H4-S1 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044023 histone-serine kinase activity (H4-S1 specific)|histone serine kinase activity (H4-S1 specific) Catalysis of the transfer of a phosphate group to the serine-1 residue of the N-terminal tail of histone H4. GO:0044024 histone kinase activity (H2A-S1 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044024 histone serine kinase activity (H2A-S1 specific)|histone-serine kinase activity (H2A-S1 specific) Catalysis of the transfer of a phosphate group to the serine-1 residue of the N-terminal tail of histone H2A. CHEBI:23792 dihydroxypteridine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23792 GO:0044021 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044021 GO:0044022 histone kinase activity (H3-S28 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044022 histone serine kinase activity (H3-S28 specific)|histone-serine kinase activity (H3-S28 specific) Catalysis of the transfer of a phosphate group to the serine-28 residue of the N-terminal tail of histone H3. CHEBI:33113 tetrathionate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33113 CHEBI:33114 disulfane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33114 GO:0044029 hypomethylation of CpG island biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044029 DNA hypomethylation of CpG island An decrease in the epigenetic methylation of cytosine and adenosine residues in a CpG island in DNA. CpG islands are genomic regions that contain a high frequency of the CG dinucleotide and are often associated with the transcription start site of genes. GO:0009709 terpenoid indole alkaloid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009709 terpenoid indole alkaloid biosynthesis|terpenoid indole alkaloid anabolism|terpenoid indole alkaloid synthesis|terpenoid indole alkaloid formation The chemical reactions and pathways resulting in the formation of terpenoid indole alkaloids, compounds formed from the condensation of tryptamine (derived from tryptophan) and secologanin (derived from geranyl pyrophosphate). GO:0044030 regulation of DNA methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044030 Any process that modulates the frequency, rate or extent of the covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine. GO:0044031 modification by symbiont of host protein by phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044031 The process in which an organism adds a phosphate group to a protein of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0044038 cell wall macromolecule biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044038 cell wall macromolecule biosynthesis|cell wall macromolecule anabolism|cell wall macromolecule synthesis|cell wall macromolecule biosynthetic process at cellular level|cellular cell wall macromolecule biosynthetic process The chemical reactions and pathways resulting in the formation of a macromolecule destined to form part of a cell wall. GO:0044039 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044039 GO:0044036 cell wall macromolecule metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044036 cellular cell wall macromolecule metabolic process|cellular cell wall macromolecule metabolism The chemical reactions and pathways involving macromolecules forming, or destined to form, part of the cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. GO:0044037 multi-organism cell wall macromolecule metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044037 multi-organism cell wall macromolecule metabolism The chemical reactions and pathways involving macromolecules forming, or destined to form, part of a cell wall, involving more than one organism. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. GO:0044034 obsolete multi-organism biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044034 multi-organism biosynthesis|multi-organismal biosynthesis|multi-organismal biosynthetic process OBSOLETE. A biosynthetic process - chemical reactions and pathways resulting in the formation of substances - which involves more than one organism. GO:0044035 multi-organism catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044035 multi-organismal catabolic process|multi-organism catabolism|multi-organismal catabolism A catabolic process - chemical reactions and pathways resulting in the breakdown of substances - which involves more than one organism. GO:0044032 modulation by symbiont of indole acetic acid levels in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044032 modulation by symbiont of IAA levels in host|modulation by symbiont of auxin levels in host The alteration by an organism of the levels of indole acetic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0044033 multi-organism metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044033 multi-organism metabolism|multi-organismal metabolism|multi-organismal metabolic process A metabolic process - chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances - which involves more than one organism. GO:0009700 indole phytoalexin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009700 indole phytoalexin biosynthesis|indole phytoalexin anabolism|indole phytoalexin synthesis|indole phytoalexin formation The chemical reactions and pathways resulting in the formation of indole phytoalexins, any indole compound produced by plants as part of their defense response. GO:0009701 isoflavonoid phytoalexin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009701 isoflavonoid phytoalexin biosynthesis|isoflavonoid phytoalexin anabolism|isoflavonoid phytoalexin synthesis|isoflavonoid phytoalexin formation The chemical reactions and pathways resulting in the formation of isoflavonoid phytoalexins, a group of water-soluble phenolic derivatives isomeric with flavonoids that possess antibiotic activity and are produced by plant tissues in response to infection. GO:0009702 L-arabinokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009702 KEGG_REACTION:R01754|EC:2.7.1.46|RHEA:20153|MetaCyc:L-ARABINOKINASE-RXN L-arabinokinase (phosphorylating)|ATP:L-arabinose 1-phosphotransferase activity Catalysis of the reaction: L-arabinose + ATP = beta-L-arabinose 1-phosphate + ADP + 2 H(+). GO:0009703 nitrate reductase (NADH) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009703 RHEA:17913|MetaCyc:NITRATE-REDUCTASE-NADH-RXN|EC:1.7.1.1 assimilatory NADH: nitrate reductase activity|assimilatory nitrate reductase activity|assimilatory NADH:nitrate reductase activity|NADH:nitrate reductase activity|NADH:nitrate oxidoreductase activity|nitrite:NAD+ oxidoreductase activity|NADH-dependent nitrate reductase activity|nitrate reductase (NADH(2)) activity|NADH-nitrate reductase activity|nitrate reductase (NADH2) Catalysis of the reaction: nitrite + NAD+ + H2O = nitrate + NADH + H+. GO:0009704 de-etiolation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009704 The greening response of plants grown in the dark (etiolated) as a result of chloroplast biogenesis and the accumulation of chlorophyll. GO:0009705 plant-type vacuole membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009705 tonoplast|membrane of vacuole with cell cycle-independent morphology|vacuolar membrane The lipid bilayer surrounding a vacuole that retains the same shape regardless of cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this component is found in Arabidopsis thaliana. GO:0009706 chloroplast inner membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009706 chloroplast inner envelope The inner, i.e. lumen-facing, lipid bilayer of the chloroplast envelope; also faces the chloroplast stroma. CHEBI:1372 1-pyrroline-5-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_1372 GO:0009707 chloroplast outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009707 chloroplast outer envelope The outer, i.e. cytoplasm-facing, lipid bilayer of the chloroplast envelope. GO:0009708 benzyl isoquinoline alkaloid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009708 benzyl isoquinoline alkaloid anabolism|benzyl isoquinoline alkaloid synthesis|benzyl isoquinoline alkaloid biosynthesis|benzyl isoquinoline alkaloid formation The chemical reactions and pathways resulting in the formation of benzyl isoquinoline alkaloids, compounds with bicyclic N-containing aromatic rings. GO:0044041 multi-organism carbohydrate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044041 multi-organism carbohydrate degradation|multi-organism carbohydrate breakdown|multi-organism carbohydrate catabolism The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, involving more than one organism. GO:0044042 glucan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044042 glucan metabolism The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues. GO:0044040 multi-organism carbohydrate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044040 main pathways of carbohydrate metabolic process|main pathways of carbohydrate metabolism|multi-organism carbohydrate metabolism The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, that involve more than one organism. CHEBI:23778 dihydroxybenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23778 CHEBI:23775 dihydroxy-5beta-cholanic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23775 CHEBI:23776 dihydroxyacetophenone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23776 GO:0044049 obsolete interaction with host via protein secreted by type VI secretion system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044049 OBSOLETE. An interaction with the host organism mediated by a substance secreted by the other (symbiont) organism via a type VI secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0044047 obsolete interaction with host via protein secreted by type I secretion system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044047 OBSOLETE. An interaction with the host organism mediated by a substance secreted by the other (symbiont) organism via a type I secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0044048 obsolete interaction with host via protein secreted by type V secretion system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044048 OBSOLETE. An interaction with the host organism mediated by a substance secreted by the other (symbiont) organism via a type V secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0044045 obsolete interaction with host via substance in symbiont cell outer membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044045 OBSOLETE. An interaction with the host organism mediated by a substance in the symbiont cell outer membrane - a lipid bilayer that forms the outermost layer of the symbiont cell envelope. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0044046 obsolete interaction with host via substance released outside of symbiont biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044046 interaction with host via substance released outside of symbiont cells OBSOLETE. An interaction with the host organism mediated by a substance that is released by the other organism. This includes substances that are released via pathogen cell lysis. GO:0044043 multi-organism glucan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044043 multi-organism glucan metabolism The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues, involving more than one organism. GO:0044044 obsolete interaction with host via substance in symbiont surface biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044044 OBSOLETE. An interaction with the host organism mediated by a substance on the surface of the other (symbiont) organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0044052 obsolete interaction with host via substance released by membrane budding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044052 interaction with host via substance released by symbiont membrane budding OBSOLETE. An interaction with the host organism mediated by a substance released via symbiont membrane budding, the evagination of a membrane resulting in formation of a vesicle. GO:0044053 translocation of peptides or proteins into host cell cytoplasm biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044053 transport of peptides or proteins into host cell cytoplasm|translocation of symbiont peptides or proteins into host cell cytoplasm The directed movement of peptides or proteins produced by a symbiont organism to a location within the host cell cytoplasm. GO:0044050 obsolete interaction with host via substance released by sporangium lysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044050 interaction with host via substance released by lysis of symbiont sporangium|interaction with host via substance released by sporangia lysis OBSOLETE. An interaction with the host organism mediated by a substance released via rupture of symbiont sporangia, structures producing and containing spores. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0044051 obsolete interaction with host via substance released by symbiont cytolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044051 interaction with host via substance released by cytolysis of symbiont OBSOLETE. An interaction with the host organism mediated by a substance released via cytolysis of symbiont cells. Cytolysis is the rupture of cell membranes and the loss of cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:23783 naphthalenediols biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23783 GO:0044058 regulation of digestive system process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044058 Any process that modulates the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. GO:0044059 modulation by symbiont of host endocrine process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044059 regulation by symbiont of host endocrine process The alteration by a symbiont organism of the functioning of a endocrine process, any of the hormonal, neural, and secretory processes that release products into the blood or lymph, in the host organism. GO:0044056 modulation by symbiont of host digestive system process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044056 regulation by symbiont of host digestive system process The alteration by a symbiont organism of the functioning of a digestive system process, a physical, chemical, or biochemical process carried out by the host organism to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. GO:0044057 regulation of system process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044057 Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system. CHEBI:23781 dihydroxyindole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23781 GO:0044054 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044054 GO:0044055 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044055 UBERON:0004990 mucosa of ascending colon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004990 mucous membrane of ascending colon|ascending colon mucosa|mucosa of organ of ascending colon|organ mucosa of ascending colon|ascending colon mucosa of organ|ascending colon organ mucosa|ascending colon mucous membrane A mucosa that is part of an ascending colon [Automatically generated definition]. UBERON:0004991 mucosa of transverse colon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004991 transverse colon mucous membrane|organ mucosa of transverse colon|transverse colon organ mucosa|mucosa of organ of transverse colon|transverse colon mucosa|mucous membrane of transverse colon|transverse colon mucosa of organ A mucosa that is part of a transverse colon [Automatically generated definition]. CHEBI:33101 nitrogen dioxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33101 UBERON:0004998 mucosa of pylorus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004998 stomach pyloric region mucosa of organ|organ mucosa of pyloric part of stomach|pyloric part of stomach mucosa of organ|stomach pyloric region mucous membrane|pylorus organ mucosa|pyloric part of stomach mucous membrane|pylorus mucosa of organ|organ mucosa of pylorus|organ mucosa of stomach pyloric region|pyloric part of stomach organ mucosa|pylorus mucous membrane|stomach pyloric region organ mucosa|antropyloric mucosa|mucous membrane of pyloric part of stomach|mucosa of pyloric part of stomach|pylorus mucosa|mucosa of organ of pyloric part of stomach|mucosa of organ of stomach pyloric region|mucous membrane of pylorus|mucosa of stomach pyloric region|mucous membrane of stomach pyloric region|pyloric part of stomach mucosa|stomach pyloric region mucosa|mucosa of organ of pylorus A mucosa that is part of a pylorus [Automatically generated definition]. UBERON:0004999 mucosa of biliary tree biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004999 organ mucosa of biliary tree|mucous membrane of biliary tract|mucosa of biliary tract|biliary tract mucosa|mucosa of organ of biliary tree|mucosa of organ of biliary tract|biliary tree mucosa|mucous membrane of biliary tree|biliary tree mucosa of organ|organ mucosa of biliary tract|biliary tract mucosa of organ|biliary tree mucous membrane|biliary tract mucous membrane|biliary tract organ mucosa|biliary tree organ mucosa A mucosa that is part of a biliary tree [Automatically generated definition]. UBERON:0004997 mucosa of pyloric antrum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004997 mucosa of organ of pyloric antrum|mucous membrane of antrum of stomach|mucosa of antrum of stomach|pyloric antrum organ mucosa|mucous membrane of pyloric antrum|antral mucosa|mucosa of organ of antrum of stomach|mucosa of organ of stomach pyloric antrum|gastric antrum mucosa|pyloric antrum mucosa of organ|mucosa of stomach pyloric antrum|antrum of stomach mucosa|stomach pyloric antrum mucosa|mucous membrane of stomach pyloric antrum|pyloric antrum mucous membrane|stomach pyloric antrum mucosa of organ|organ mucosa of antrum of stomach|antrum of stomach mucosa of organ|pyloric antrum mucosa|organ mucosa of pyloric antrum|stomach pyloric antrum mucous membrane|antrum of stomach mucous membrane|organ mucosa of stomach pyloric antrum|antrum of stomach organ mucosa|stomach pyloric antrum organ mucosa A mucosa that is part of a pyloric antrum [Automatically generated definition]. UBERON:0004995 mucosa of body of stomach biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004995 mucous membrane of body of stomach|gastric body mucous membrane|gastric body mucosa|corpus gastricum (ventriculare) mucosa of organ|organ mucosa of corpus gastricum (ventriculare)|mucosa of organ of body of stomach|organ mucosa of gastric body|corpus gastricum (ventriculare) mucous membrane|mucosa of organ of stomach body|corpus gastricum (ventriculare) organ mucosa|stomach body mucosa|body of stomach mucosa|mucosa of stomach body|mucous membrane of stomach body|body of stomach mucosa of organ|organ mucosa of body of stomach|stomach body mucosa of organ|gastric body organ mucosa|mucous membrane of corpus gastricum (ventriculare)|mucosa of organ of gastric body|mucosa of corpus gastricum (ventriculare)|body of stomach mucous membrane|mucosa of gastric body|stomach body mucous membrane|mucosa of organ of corpus gastricum (ventriculare)|mucous membrane of gastric body|corpus gastricum (ventriculare) mucosa|gastric body mucosa of organ|stomach body organ mucosa|body of stomach organ mucosa|organ mucosa of stomach body A mucosa that is part of a body of stomach [Automatically generated definition]. UBERON:0004992 mucosa of descending colon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004992 organ mucosa of descending colon|descending colon mucosa|mucosa of organ of descending colon|mucous membrane of descending colon|descending colon mucosa of organ|descending colon organ mucosa|descending colon mucous membrane A mucosa that is part of a descending colon [Automatically generated definition]. UBERON:0004993 mucosa of sigmoid colon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004993 sigmoid colon mucous membrane|sigmoid colon organ mucosa|mucous membrane of sigmoid colon|mucosa of organ of sigmoid colon|sigmoid colon mucosa|sigmoid colon mucosa of organ|organ mucosa of sigmoid colon A mucosa that is part of a sigmoid colon [Automatically generated definition]. UBERON:0014382 collection of hairs on head or neck biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014382 A collection of hairs that is part of a craniocervical region. GO:0044063 modulation by symbiont of host nervous system process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044063 modulation by symbiont of host neurological system process|regulation by symbiont of host neurological system process The alteration by a symbiont organism of the functioning of a host neurophysiological process, an organ system process carried out by any of the organs or tissues of neurological system. GO:0044064 modulation by symbiont of host respiratory system process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044064 regulation by symbiont of host respiratory system process The alteration by a symbiont organism of the functioning of a respiratory system process, an organ system process carried out by any of the organs or tissues of the respiratory system. GO:0044061 modulation by symbiont of host excretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044061 regulation by symbiont of host excretion The alteration by a symbiont organism of the functioning of excretion, the elimination by the host organism of the waste products that arise as a result of metabolic activity. CHEBI:23750 S-substituted dihydrolipoamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23750 GO:0044062 regulation of excretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044062 Any process that modulates the frequency, rate, or extent of excretion, the elimination by an organism of the waste products that arise as a result of metabolic activity. GO:0044060 regulation of endocrine process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044060 regulation of endocrine system process Any process that modulates the frequency, rate or extent of an endocrine process, a process involving the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system. CHEBI:47724 vancomycin aglycone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47724 GO:0044069 modulation by symbiont of host anion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044069 modification of host anion transport by symbiont The process in which a symbiont organism modulates the anion transport, the directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, of its host organism. GO:0044067 modification by symbiont of host intercellular junctions biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044067 modification of host intercellular junctions by symbiont The process in which a symbiont organism effects a change in the structure or function of its host intercellular junction, a specialized region of connection between two cells. GO:0044068 modulation by symbiont of host cellular process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044068 modulation of host cellular process by symbiont|regulation by symbiont of host cellular process|regulation of host cellular process by symbiont Any process in which a symbiont organism modulates the frequency, rate or extent of a cellular process, any process that is carried out at the cellular level, but not necessarily restricted to a single cell, in its host organism. UBERON:0014387 mesenchyme derived from neural crest biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014387 neural crest derived mesenchyme|mesenchyme from neural crest|neural crest mesenchyme Mesenchyme that develops_from the neural crest[Automatically generated definition]. UBERON:0014388 kidney collecting duct epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014388 epithelium of collecting duct of renal tubule|collecting duct of renal tubule epithelium|epithelium of renal collecting tubule The simple cuboidal epithelium lining the lumen of kidney collecting ducts. GO:0044065 regulation of respiratory system process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044065 Any process that modulates the frequency, rate or extent of a respiratory system process, an organ system process carried out by any of the organs or tissues of the respiratory system. UBERON:0014389 gustatory papilla of tongue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014389 gustatory papillae|taste papillae|taste papilla|gustatory papilla A papilla that contain taste buds, including the fungiform, foliate, and circumvallate papillae. GO:0044066 modification by symbiont of host cell nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044066 modification of host cell nucleus by symbiont|modification by symbiont of host nucleus|modification of host nucleus by symbiont The process in which a symbiont organism effects a change in the structure or function of its host cell nucleus. GO:0044074 negative regulation by symbiont of host translation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044074 negative regulation of host translation by symbiont The process in which a symbiont organism stops, prevents, or reduces the frequency, rate or extent of translation, the chemical reactions and pathways resulting in the formation of a protein, in its host organism. UBERON:0014371 future telencephalon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0014371 presumptive telencephalon Embryonic structure that gives rise to the telencephalon. GO:0044075 modulation by symbiont of host vacuole organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044075 modulation of host vacuole organization by symbiont|regulation by symbiont of host vacuole organization|modulation by symbiont of host vacuole biogenesis|modulation by symbiont of host vacuole organisation Any process in which a symbiont organism modulates the frequency, rate or extent of vacuole organization in its host organism. CHEBI:23763 pyrroline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23763 GO:0044072 negative regulation by symbiont of host cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044072 The process in which a symbiont organism stops, prevents or reduces the rate or extent of its host's progression through its cell cycle via direct interactions with the host cell macromolecular machinery. GO:0044073 modulation by symbiont of host translation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044073 regulation by symbiont of host translation|modification by symbiont of host translation|modulation of host translation by symbiont The process in which a symbiont organism effects a change in translation, the chemical reactions and pathways resulting in the formation of a protein, in its host organism. GO:0044070 regulation of anion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044070 Any process that modulates the frequency, rate or extent of the directed movement of anions, atoms or small molecules with a net negative charge into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0044071 modulation by symbiont of host cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044071 regulation by symbiont of host cell cycle|modulation of host cell cycle by symbiont|modification by symbiont of host cell cycle The process in which a symbiont organism effects a change in its host's cell cycle through direct interactions with the host cell macromolecular machinery. CHEBI:23765 quinolone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23765 GO:0044078 positive regulation by symbiont of host receptor-mediated endocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044078 positive regulation of host receptor-mediated endocytosis by symbiont Any process in which a symbiont organism activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport, in its host organism. GO:0044079 modulation by symbiont of host neurotransmitter secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044079 regulation by symbiont of host neurotransmitter secretion|modification by symbiont of host neurotransmitter secretion|modulation of host neurotransmitter secretion by symbiont Any process in which a symbiont organism modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell in its host organism. GO:0044076 positive regulation by symbiont of host vacuole organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044076 positive regulation by symbiont of host vacuole biogenesis|positive regulation by symbiont of host vacuole organisation|positive regulation of host vacuole organization by symbiont The process in which a symbiont organism activates or increases the frequency, rate or extent of vacuole organization in its host organism. GO:0044077 modulation by symbiont of host receptor-mediated endocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044077 regulation by symbiont of host receptor-mediated endocytosis|modulation of host receptor-mediated endocytosis by symbiont The process in which a symbiont organism modulates the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport, in its host organism. GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0093001 The chemical reactions and pathways resulting in the breakdown of a storage polysaccharide into pyruvate through a glucose-1-phosphate intermediate, with the concomitant production of a small amount of ATP and the reduction of NAD to NADH. GO:0093002 response to nematicide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0093002 response to nematocide|response to antihelmintic Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nematicide stimulus. Nematicides are chemicals used to kill nematodes. GO:0044085 cellular component biogenesis biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0044085 cellular component biogenesis at cellular level A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component. GO:0044086 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044086 CHEBI:23730 5-oxo-2-furylacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23730 GO:0044083 modulation by symbiont of host Rho protein signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044083 modulation of host Rho protein signaling by symbiont|modulation of host Rho protein signal transduction by symbiont|modulation by symbiont of host Rho protein mediated signal transduction|modulation of host Rho protein signalling by symbiont|regulation by symbiont of host Rho protein signal transduction|modulation by symbiont of host Rho protein-mediated signal transduction Any process in which a symbiont organism modulates the frequency, rate or extent of Rho protein signal transduction in its host organism. GO:0044084 host cell membrane pore complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044084 pore complex in host cell membrane Any small opening in a host cell membrane that allows the passage of gases and/or liquids, composed of host proteins. GO:0044081 modulation by symbiont of host nitric oxide-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044081 modulation by symbiont of host nitric oxide mediated signal transduction|regulation by symbiont of host nitric oxide-mediated signal transduction|modulation of host nitric oxide-mediated signaling by symbiont|modulation of host nitric oxide-mediated signal transduction by symbiont|modulation of host nitric oxide-mediated signalling by symbiont Any process in which a symbiont organism modulates the rate, frequency or extent of nitric oxide mediated signal transduction in its host organism. Nitric oxide mediated signal transduction is a series of molecular signals mediated by the detection of nitric oxide (NO). CHEBI:23733 dihydrocarvone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_23733 GO:0044082 modulation by symbiont of host small GTPase mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044082 regulation by symbiont of host small GTPase mediated signal transduction|modulation of host small GTPase mediated signal transduction by symbiont Any process in which a symbiont organism modulates the frequency, rate or extent of small GTPase mediated signal transduction in its host organism. GO:0044080 modulation by symbiont of host cGMP-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044080 modulation by symbiont of host cGMP-mediated signal transduction pathway|modulation by symbiont of host cGMP-mediated signalling|modulation by symbiont of host cGMP-mediated signaling|modulation of host cGMP-mediated signal transduction by symbiont|regulation by symbiont of host cGMP-mediated signal transduction Any process in which a symbiont organism modulates the rate, frequency or extent of cGMP-mediated signaling in its host organism. cGMP-mediated signaling is a series of molecular signals in which a cell uses cyclic GMP to convert an extracellular signal into a response. GO:0044089 positive regulation of cellular component biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044089 Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. GO:0044087 regulation of cellular component biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044087 Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. GO:0044088 regulation of vacuole organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044088 regulation of vacuole biogenesis|regulation of vacuole organisation Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole. CHEBI:1387 3,4-dihydroxyphenylethyleneglycol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_1387 CHEBI:23738 dihydrophenanthrenediol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23738 CHEBI:23736 4,5-dihydrocortisone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_23736 GO:0044096 type IV pilus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044096 type IV fimbriae|type 4 pilus|TFP A short filamentous structure on the surface of a bacterial cell distinguished from other pili by post-translational N-methylation of the pilin monomers. GO:0044097 secretion by the type IV secretion system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044097 secretion via the type IV secretion system The controlled release of proteins or DNA by a cell, via the type IV secretion system. CHEBI:23741 dihydrodipicolinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23741 GO:0044094 host cell nuclear part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044094 Any constituent part of a host cell's nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. The host is the larger of the organisms involved in a symbiotic interaction. GO:0044095 host cell nucleoplasm biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044095 That part of a host cell's nuclear content other than the chromosomes or the nucleolus. The host is the larger of the organisms involved in a symbiotic interaction. GO:0044092 negative regulation of molecular function biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044092 Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. GO:0044093 positive regulation of molecular function biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044093 Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. GO:0044090 positive regulation of vacuole organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044090 positive regulation of vacuole biogenesis|positive regulation of vacuole organisation Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole. GO:0044091 membrane biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044091 A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a membrane. CHEBI:23743 dihydrofolic acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23743 GO:0044098 DNA secretion by the type IV secretion system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044098 DNA secretion via the type IV secretion system The controlled release of DNA by a cell, via the type IV secretion system. GO:0044099 polar tube biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044099 A highly specialized structure unique to microsporidia that is required for host cell invasion. In the spore, the polar tube is connected at the anterior end, and then coils around the sporoplasm. Upon appropriate environmental stimulation, the polar tube rapidly discharges out of the spore, pierces a cell membrane and serves as a conduit for sporoplasm passage into the new host cell. CHEBI:1395 3,5-dibromo-4-hydroxybenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_1395 CHEBI:72687 bacilysin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72687 GO:0010888 negative regulation of lipid storage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010888 Any process that decreases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development. GO:0034855 4-AD 9alpha-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034855 UM-BBD_reactionID:r1153|EC:1.14.15.- Catalysis of the reaction: androst-4-ene-3,17-dione + O2 + 2 H+ + 2 e- = 9alpha-hydroxy-4-androstene-3,17-dione + H2O. GO:0010889 regulation of sequestering of triglyceride biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010889 regulation of sequestering of triacylglycerol|regulation of triacylglycerol sequestration Any process that modulates the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system. GO:0034856 2-hydroxyhexa-2,4-dienoate hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034856 RHEA:32535|UM-BBD_reactionID:r1281|EC:4.2.1.132 Catalysis of the reaction: (2E,4E)-2-hydroxyhexa-2,4-dienoate + H2O = 4-hydroxy-2-oxohexanoate. GO:0010886 positive regulation of cholesterol storage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010886 positive regulation of cholesterol sequestration Any process that increases the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. GO:0034857 2-(methylthio)benzothiazole monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034857 UM-BBD_reactionID:r1287 Catalysis of the reaction: 2-(methylthio)benzothiazole + 1/2 O2 = 2-(methylsulfinyl)benzothiazole. GO:0010887 negative regulation of cholesterol storage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010887 negative regulation of cholesterol sequestration Any process that decreases the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. GO:0034858 2-hydroxybenzothiazole monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034858 UM-BBD_reactionID:r1291 Catalysis of the reaction: 2-hydroxybenzothiazole + 1/2 O2 = 2,6-dihydroxybenzothiazole. GO:0034859 benzothiazole monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034859 UM-BBD_reactionID:r1292 Catalysis of the reaction: benzothiazole + 1/2 O2 = 2-hydroxybenzothiazole. GO:0009891 positive regulation of biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009891 up regulation of biosynthetic process|positive regulation of anabolism|upregulation of biosynthetic process|positive regulation of synthesis|positive regulation of formation|stimulation of biosynthetic process|activation of biosynthetic process|up-regulation of biosynthetic process|positive regulation of biosynthesis Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances. GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010880 Any process that modulates the rate, frequency or extent of release of sequestered calcium ion into cytosol by the sarcoplasmic reticulum, the process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels. GO:0009892 negative regulation of metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009892 negative regulation of multicellular organismal metabolic process|inhibition of metabolic process|down regulation of metabolic process|inhibition of organismal metabolic process|negative regulation of organismal metabolism|downregulation of metabolic process|negative regulation of metabolism|down-regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010881 Any process that modulates the frequency, rate or extent of cardiac muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction. GO:0009893 positive regulation of metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolism|up-regulation of metabolic process|positive regulation of multicellular organismal metabolic process|positive regulation of organismal metabolism|upregulation of metabolic process|up-regulation of organismal metabolic process|up regulation of metabolic process|activation of metabolic process|stimulation of organismal metabolic process|stimulation of metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. GO:0009894 regulation of catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolism|regulation of degradation|regulation of breakdown Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances. GO:0034850 isooctane monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034850 EC:1.13.12.-|UM-BBD_reactionID:r1269 Catalysis of the reaction: isooctane + 1/2 O2 = 2,4,4-trimethyl-1-pentanol. GO:0009895 negative regulation of catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009895 negative regulation of breakdown|down-regulation of catabolic process|inhibition of catabolic process|negative regulation of catabolism|down regulation of catabolic process|negative regulation of degradation|downregulation of catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances. GO:0034851 2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034851 UM-BBD_reactionID:r1274 Catalysis of the reaction: 2,4,4-trimethyl-3-oxopentanoyl-CoA + CoASH = pivalyl-CoA + propanoyl-CoA. GO:0010884 positive regulation of lipid storage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010884 positive regulation of lipid sequestration Any process that increases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development. GO:0019218 regulation of steroid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019218 regulation of steroid metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving steroids. GO:0009896 positive regulation of catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009896 up regulation of catabolic process|activation of catabolic process|stimulation of catabolic process|up-regulation of catabolic process|upregulation of catabolic process|positive regulation of degradation|positive regulation of catabolism|positive regulation of breakdown Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances. GO:0019219 regulation of nucleobase-containing compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism|regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. GO:0034852 4,4-dimethyl-3-oxopentanal dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034852 UM-BBD_reactionID:r1309 Catalysis of the reaction: 4,4-dimethyl-3-oxopentanal + H2O = 4,4-dimethyl-3-oxopentanoate + 3 H+ + 2 e-. GO:0010885 regulation of cholesterol storage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010885 Any process that modulates the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. GO:0009897 external side of plasma membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009897 juxtamembrane|outer surface of cytoplasmic membrane|external leaflet of plasma membrane The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface. GO:0034853 2,4,4-trimethyl-3-oxopentanoate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034853 UM-BBD_reactionID:r1278 Catalysis of the reaction: 2,4,4-trimethyl-3-oxopentanoate + H+ = 2,2-dimethyl-3-pentanone + CO2. GO:0019216 regulation of lipid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019216 regulation of lipid metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids. GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010882 regulation of cardiac muscle contraction by calcium ion signalling Any process that modulates the frequency, rate or extent of cardiac muscle contraction by changing the calcium ion signals that trigger contraction. GO:0009898 cytoplasmic side of plasma membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009898 juxtamembrane|internal leaflet of plasma membrane|internal side of plasma membrane The leaflet the plasma membrane that faces the cytoplasm and any proteins embedded or anchored in it or attached to its surface. GO:0010883 regulation of lipid storage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010883 regulation of lipid sequestration Any process that modulates the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development. GO:0019217 regulation of fatty acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019217 regulation of fatty acid metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving fatty acids. GO:0034854 4,4-dimethyl-3-oxopentanoate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034854 UM-BBD_reactionID:r1280 Catalysis of the reaction: 4,4-dimethyl-3-oxopentanoate + H+ = 3,3-dimethyl-2-butanone + CO2. GO:0009899 ent-kaurene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009899 MetaCyc:4.2.3.19-RXN|KEGG_REACTION:R05092|EC:4.2.3.19|RHEA:22220 ent-kaurene synthase B activity|ent-copalyl-diphosphate diphosphate-lyase (cyclizing)|ent-kaurene synthetase B activity|ent-copalyl-diphosphate diphosphate-lyase (cyclizing, ent-kaurene-forming) Catalysis of the reaction: ent-copalyl diphosphate = ent-kaur-16-ene + diphosphate. GO:0019214 obsolete surfactant activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019214 surfactant activity OBSOLETE. The action of reducing the surface tension of a liquid. PO:0008016 vegetative shoot apical meristem biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0008016 meristema vegetativo apical del epiblasto (epiblastema) (Spanish, exact)|vegetative meristem (related)|栄養シュート頂端分裂組織 (Japanese, exact) A shoot apical meristem (PO:0020148) that gives rise to the apical growth of vegetative tissues and organs. CHEBI:33070 indole-3-butyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33070 GO:0019215 intermediate filament binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019215 Interacting selectively and non-covalently with an intermediate filament, a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of higher eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. GO:0019212 phosphatase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019212 Stops, prevents or reduces the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule. GO:0019213 deacetylase activity biolink:MolecularActivity go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0019213 Reactome:R-HSA-5689000 Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule. CHEBI:72681 (3S)-versiconol acetate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72681 GO:0019210 kinase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019210 Stops, prevents or reduces the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule. CHEBI:72682 1-lauroyl-sn-glycerol 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72682 GO:0019211 phosphatase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019211 Increases the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule. CHEBI:72683 1-myristoyl-sn-glycerol 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72683 CHEBI:33076 D-mannonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33076 CHEBI:72696 cyanidin 3-O-[6-O-(4-O-beta-D-glucosyl-p-coumaroyl)-2-O-(2-O-sinapoyl-beta-D-xylosyl)-beta-D-glucosyl]-5-O-(6-O-malonyl-beta-D-glucoside) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72696 CHEBI:72697 (2R)-dihomocitrate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72697 CHEBI:72698 (2R)-trihomocitric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72698 CHEBI:72699 (2R)-trihomocitrate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72699 GO:0010899 regulation of phosphatidylcholine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010899 Any process that modulates the rate, frequency or extent of phosphatidylcholine catabolism. Phosphatidylcholine catabolic processes are the chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. GO:0034844 naphthyl-2-methyl-succinate CoA-transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034844 UM-BBD_reactionID:r1256 Catalysis of the reaction: naphthyl-2-methyl-succinate + succinyl-CoA = naphthyl-2-methyl-succinyl-CoA + succinate. GO:0034845 naphthyl-2-methyl-succinyl-CoA dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034845 EC:1.3.99.-|UM-BBD_reactionID:r1258 Catalysis of the reaction: naphthyl-2-methyl-succinyl-CoA = naphthyl-2-methylene-succinyl-CoA + 2 H+ + 2 e-. GO:0010897 negative regulation of triglyceride catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010897 negative regulation of triacylglycerol catabolic process Any process that decreases the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride. GO:0034846 naphthyl-2-methylene-succinyl-CoA lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034846 UM-BBD_reactionID:r1259 Catalysis of the reaction: naphthyl-2-methylene-succinyl-CoA + H2O = naphthyl-2-hydroxymethyl-succinyl-CoA. GO:0010898 positive regulation of triglyceride catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010898 positive regulation of triacylglycerol catabolic process Any process that increases the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride. GO:0034847 naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034847 UM-BBD_reactionID:r1260 Catalysis of the reaction: naphthyl-2-hydroxymethyl-succinyl-CoA = naphthyl-2-oxomethyl-succinyl-CoA + 2 H+ + 2 e-. GO:0034848 naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034848 UM-BBD_reactionID:r1261 Catalysis of the reaction: naphthyl-2-oxomethyl-succinyl-CoA + CoASH = 2-naphthoyl-CoA + succinyl-CoA. GO:0034849 2-naphthoate CoA-transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034849 UM-BBD_reactionID:r1262 Catalysis of the reaction: 2-naphthoyl-CoA + OH- = 2-naphthoate + CoASH. GO:0010891 negative regulation of sequestering of triglyceride biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010891 negative regulation of sequestering of triacylglycerol|negative regulation of triglyceride sequestration Any process that decreases the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system. GO:0010892 positive regulation of mitochondrial translation in response to stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010892 Any process that activates or increases the frequency, rate or extent of mitochondrial translation as a result of a stimulus indicating the organism is under stress. GO:0010890 positive regulation of sequestering of triglyceride biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010890 positive regulation of triglyceride sequestration|positive regulation of sequestering of triacylglycerol Any process that increases the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system. GO:0019229 regulation of vasoconstriction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019229 Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels. GO:0010895 negative regulation of ergosterol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010895 Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol. GO:0034840 3-hydroxymenthone dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034840 UM-BBD_reactionID:r1185 Catalysis of the reaction: (5R)-3-hydroxymenthone + NAD+ = mentha-1,3-dione + NADH + H+. GO:0034841 mentha-1,3-dione-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034841 UM-BBD_reactionID:r1186 Catalysis of the reaction: mentha-1,3-dione + CoASH = 3,7-dimethyl-5-oxo-octyl-CoA. GO:0010896 regulation of triglyceride catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010896 regulation of triacylglycerol catabolic process Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride. GO:0034842 thiophene-2-carboxylate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034842 UM-BBD_reactionID:r1234 Catalysis of the reaction: thiophene-2-carboxylate + ATP + CoASH = thiophene-2-carboxyl-CoA + AMP + PPi. GO:0010893 positive regulation of steroid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010893 Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. GO:0019227 neuronal action potential propagation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019227 The propagation of an action potential along an axon, away from the soma. GO:0010894 negative regulation of steroid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010894 Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. GO:0034843 2-oxoglutaryl-CoA thioesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034843 UM-BBD_reactionID:r1238 Catalysis of the reaction: 2-oxoglutaryl-CoA + OH- = 2-oxoglutarate + CoASH. GO:0019228 neuronal action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019228 generation of action potential An action potential that occurs in a neuron. GO:0019225 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019225 GO:0019226 transmission of nerve impulse biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019226 conduction of nerve impulse|signal transmission along a neuron The neurological system process in which a signal is transmitted through the nervous system by a combination of action potential propagation and synaptic transmission. GO:0019223 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019223 CHEBI:33082 phenalene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33082 GO:0019224 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019224 GO:0019221 cytokine-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019221 cytokine and chemokine mediated signaling pathway|cytokine mediated signalling pathway A series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. CHEBI:72692 polyunsaturated fatty aldehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72692 GO:0019222 regulation of metabolic process biolink:BiologicalProcess go-plus goslim_metagenomics http://purl.obolibrary.org/obo/GO_0019222 regulation of organismal metabolic process|regulation of metabolism|regulation of multicellular organismal metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. CHEBI:72694 (2R)-dihomocitric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72694 GO:0019220 regulation of phosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019220 regulation of phosphate metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates. CHEBI:72695 organic molecule biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72695 GO:0010866 regulation of triglyceride biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010866 regulation of triacylglycerol biosynthetic process Any process that modulates the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol. GO:0044203 host cell nuclear lamina biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044203 The fibrous, electron-dense layer lying on the nucleoplasmic side of the inner membrane of a host cell nucleus, composed of lamin filaments. GO:0034833 geranylate CoA-transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034833 UM-BBD_reactionID:r1165 Catalysis of the reaction: geranylate + CoASH = trans-geranyl-CoA + OH-. GO:0044204 host cell nuclear matrix biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044204 The dense fibrillar network lying on the inner side of the host nuclear membrane. GO:0034834 2-mercaptobenzothiazole dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034834 EC:1.13.11.-|UM-BBD_reactionID:r1177 Catalysis of the reaction: 2-mercaptobenzothiazole + O2 + 2 H+ + 2 e- = 2-mercaptobenzothiazole-cis-6,7-dihydrodiol. GO:0010867 positive regulation of triglyceride biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010867 positive regulation of triacylglycerol biosynthetic process Any process that increases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol. GO:0034835 2-mercaptobenzothiazole monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034835 EC:1.13.12.-|UM-BBD_reactionID:r1178 Catalysis of the reaction: 2-mercaptobenzothiazole + 1/2 O2 = 6-hydroxy-2-mercaptobenzothiazole. GO:0010864 positive regulation of protein histidine kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010864 Any process that increases the frequency, rate or extent of protein histidine kinase activity. GO:0044201 host cell nuclear inner membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044201 The inner, i.e. lumen-facing, lipid bilayer of the host nuclear envelope. GO:0034836 6-hydroxy-2-mercaptobenzothiazole monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034836 EC:1.13.12.-|UM-BBD_reactionID:r1181 Catalysis of the reaction: 6-hydroxy-2-mercaptobenzothiazole + 1/2 O2 = 6,7-dihydroxy-2-mercaptobenzothiazole. GO:0044202 host cell nuclear outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044202 The outer, i.e. cytoplasm-facing, lipid bilayer of the host nuclear envelope; continuous with the endoplasmic reticulum of the host cell and sometimes studded with ribosomes. GO:0010865 stipule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010865 The process whose specific outcome is the progression of the stipule over time, from its formation to the mature structure. A stipule is one of (usually) a pair of appendages at the bases of leaves in many broad-leaved angiosperms. GO:0034837 2-mercaptobenzothiazole-cis-6,7-dihydrodiol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034837 UM-BBD_reactionID:r1179 Catalysis of the reaction: 2-mercaptobenzothiazole-cis-6,7-dihydrodiol = 6,7-dihydroxy-2-mercaptobenzothiazole + 2 H+ + 2 e-. GO:0034838 menthone dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034838 UM-BBD_reactionID:r1183 Catalysis of the reaction: (-)-(2S,5R)-menthone + NAD+ = (5R)-menth-2-enone + NADH + H+. GO:0044200 host cell nuclear membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044200 Either of the lipid bilayers that surround the host nucleus and form the nuclear envelope; excludes the intermembrane space. GO:0010868 negative regulation of triglyceride biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010868 negative regulation of triacylglycerol biosynthetic process Any process that decreases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol. GO:0034839 menth-2-enone hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034839 UM-BBD_reactionID:r1184 Catalysis of the reaction: (5R)-menth-2-enone + H2O = (5R)-3-hydroxymenthone. GO:0010869 obsolete regulation of receptor biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010869 OBSOLETE. Any process that modulates the frequency or rate of receptor biosynthesis. Receptor biosynthesis is the collection of chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. GO:0009870 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009870 CHEBI:1189 2-methoxyestrone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_1189 GO:0044209 AMP salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044209 AMP biosynthetic process via salvage pathway|adenosine monophosphate salvage The chemical reactions and pathways resulting in the formation of adenosine monophosphate (AMP) from derivatives of it (either adenine, ADP or adenosine 3',5'-bisphosphate) without de novo synthesis. GO:0009871 jasmonic acid and ethylene-dependent systemic resistance, ethylene mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009871 jasmonic acid and ethene-dependent systemic resistance, ethene mediated signaling pathway|jasmonic acid/ethylene-dependent systemic resistance, ethylene mediated signaling pathway|jasmonic acid/ethene-dependent systemic resistance, ethene mediated signaling pathway|jasmonic acid/ethene-dependent systemic resistance, ethene mediated signalling pathway|ethene mediated signaling pathway (jasmonic acid/ethene-dependent systemic resistance)|ethylene mediated signaling pathway (jasmonic acid/ethylene-dependent systemic resistance)|jasmonic acid/ethylene-dependent systemic resistance, ethylene mediated signalling pathway The series of molecular signals mediated by ethylene (ethene) involved in jasmonic acid/ethylene dependent systemic resistance. GO:0009872 obsolete gametophytic self-incompatibility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009872 gametophytic self-incompatibility OBSOLETE. A mechanism that functions to prevent self-fertilization in flowering plants that is determined by the diploid genotype of the parent plant. In sporophytic incompatibility the pollen does not germinate, consequently fertilization does not take place. GO:0009873 ethylene-activated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009873 ethylene mediated signalling pathway|ethylene mediated signaling pathway|ethene mediated signalling pathway|ethylene signaling pathway|ethene mediated signaling pathway|ethylene signal transduction A series of molecular signals generated by the reception of ethylene (ethene, C2H4) by a receptor and ending with modulation of a cellular process, e.g. transcription. GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010862 Any process that increases the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways. GO:0044207 translation initiation ternary complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044207 Met-tRNA/eIF2.GTP ternary complex|translation initiation (ternary) complex A ribonucleoprotein complex that contains aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator). GO:0044208 'de novo' AMP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044208 The chemical reactions and pathways resulting in the formation of adenosine monophosphate (AMP) from inosine 5'-monophosphate (IMP). GO:0034830 (2Z)-2,4-dihydroxydec-2-enedioate aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034830 UM-BBD_reactionID:r1174|EC:4.1.3.- Catalysis of the reaction: (2Z)-2,4-dihydroxydec-2-enedioate = pyruvate + 7-oxoheptanoate. GO:0010863 positive regulation of phospholipase C activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010863 Any process that increases the rate of phospholipase C activity. GO:0009874 obsolete sporophytic self-incompatibility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009874 sporophytic self-incompatibility OBSOLETE. A mechanism that functions to prevent self-fertilization in flowering plants that is determined by the diploid genotype of the parent plant. In sporophytic incompatibility the pollen does not germinate, consequently fertilization does not take place. GO:0044205 'de novo' UMP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044205 'de novo' UMP biosynthesis The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate, starting with the synthesis of (S)-dihydroorotate from bicarbonate; UMP biosynthesis may either occur via reduction by quinone, NAD(+) or oxygen. GO:0034831 (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034831 UM-BBD_reactionID:r1176 Catalysis of the reaction: (R)-1,2,3,4-tetrahydronaphthol = 1,2,3,4-tetrahydronaphthalone + 2 H+ + 2 e-. GO:0010860 obsolete proteasome regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010860 proteasome regulator activity OBSOLETE. Modulates the activity of the proteasome complex. The proteasome complex performs regulated ubiquitin-dependent cytosolic and nuclear proteolysis. GO:0009875 pollen-pistil interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009875 pollen-gynoecium interaction The interaction between a pollen grain and pistil. GO:0044206 UMP salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044206 UMP biosynthesis via nucleoside salvage pathway|UMP biosynthetic process via nucleoside salvage pathway Any process which produces UMP, uridine monophosphate, from derivatives of it (e.g. cytidine, uridine, cytosine) without de novo synthesis. GO:0034832 geranial dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034832 UM-BBD_reactionID:r1164 Catalysis of the reaction: geranial + NAD+ + OH- = geranylate + NADH + H+. GO:0010861 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010861 GO:0009876 pollen adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009876 The process in which pollen deposited on the stigma adheres to cells of the stigma. GO:0009877 nodulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009877 nodule morphogenesis|nodule development|nodule formation The formation of nitrogen-fixing root nodules on plant roots. GO:0009878 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009878 GO:0009879 determination of radial symmetry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009879 determination of radial asymmetry The establishment of an organism's body plan or a part of an organism such that it is symmetric around a central axis. CHEBI:1184 maleylacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_1184 GO:0034822 citronellal dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034822 UM-BBD_reactionID:r1156 Catalysis of the reaction: citronellal + NAD+ + OH- = citronellate + NADH + H+. GO:0010877 lipid transport involved in lipid storage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010877 The directed movement of lipids into cells that is part of their accumulation and maintenance. GO:0044214 spanning component of plasma membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044214 transmembrane|fully spanning plasma membrane The component of the plasma membrane consisting of gene products and protein complexes that have some part that spans both leaflets of the membrane. GO:0034823 citronellyl-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034823 KEGG_REACTION:R08088|UM-BBD_reactionID:r1157 Catalysis of the reaction: citronellate + CoASH + ATP = citronellyl-CoA + AMP + PPi. GO:0010878 cholesterol storage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010878 cholesterol sequestration|sequestration of cholesterol The accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. GO:0044215 obsolete other organism biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044215 OBSOLETE. A secondary organism with which the first organism is interacting. GO:0034824 citronellyl-CoA dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034824 UM-BBD_reactionID:r1159 Catalysis of the reaction: citronellyl-CoA + NAD+ = cis-geranyl-CoA + NADH + H+. GO:0010875 positive regulation of cholesterol efflux biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010875 Any process that increases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle. GO:0044212 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044212 GO:0034825 tetralin ring-hydroxylating dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034825 EC:1.14.12.-|UM-BBD_reactionID:r1169 Catalysis of the reaction: tetralin + O2 + NADH + H+ = cis-1,2-dihydroxy-1,2,5,6,7,8-hexahydronaphthalene + NAD+. GO:0010876 lipid localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010876 lipid localisation Any process in which a lipid is transported to, or maintained in, a specific location. GO:0044213 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044213 GO:0034826 1,2-dihydroxy-1,2,5,6,7,8-hexyhadronaphthalene dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034826 UM-BBD_reactionID:r1170 Catalysis of the reaction: cis-1,2-dihydroxy-1,2,5,6,7,8-hexahydronaphthalene + NAD+ = 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene + NADH + H+. GO:0044210 'de novo' CTP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044210 'de novo' cytidine 5'-triphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of cytidine 5'-triphosphate (CTP) from simpler components. GO:0044211 CTP salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044211 cytidine 5'-triphosphate salvage|CTP biosynthetic process via salvage pathway Any process which produces cytidine 5'-triphosphate (CTP) from derivatives of it, without de novo synthesis. GO:0034827 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene extradiol dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034827 UM-BBD_reactionID:r1171|EC:1.13.11.- Catalysis of the reaction: 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene + O2 = 4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate + H+. CHEBI:47693 keto-D-tagatose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47693 GO:0034828 4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034828 UM-BBD_reactionID:r1172 Catalysis of the reaction: 4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate + H2O = 2-hydroxydec-2,4-diene-1,10-dioate + H+. GO:0010879 cholesterol transport involved in cholesterol storage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010879 The directed movement of cholesterol into cells that is part of their accumulation and maintenance. GO:0009890 negative regulation of biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009890 downregulation of biosynthetic process|down regulation of biosynthetic process|inhibition of biosynthetic process|negative regulation of anabolism|negative regulation of synthesis|negative regulation of formation|down-regulation of biosynthetic process|negative regulation of biosynthesis Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances. GO:0034829 2-hydroxydec-2,4-diene-1,10-dioate hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034829 UM-BBD_reactionID:r1172 Catalysis of the reaction: 2-hydroxydec-2,4-diene-1,10-dioate + H2O = (2Z)-2,4-dihydroxydec-2-enedioate. GO:0009880 embryonic pattern specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009880 embryonic pattern formation|ventral/lateral system|embryonic pattern biosynthesis The process that results in the patterns of cell differentiation that will arise in an embryo. GO:0010870 obsolete positive regulation of receptor biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010870 OBSOLETE. Any process that increases the frequency or rate of receptor biosynthesis. Receptor biosynthesis is the collection of chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. GO:0009881 photoreceptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009881 short-wave-sensitive opsin|long-wave-sensitive opsin|green-sensitive opsin|UV-sensitive opsin|violet-sensitive opsin|blue-sensitive opsin|opsin|red-sensitive opsin The function of absorbing and responding to incidental electromagnetic radiation, particularly visible light. The response may involve a change in conformation. GO:0019209 kinase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019209 Binds to and increases the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule. GO:0009882 blue light photoreceptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009882 The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 400-470nm. The response may involve a change in conformation. GO:0009883 red or far-red light photoreceptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009883 red/far-red light photoreceptor activity The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 660-730nm. The response may involve a change in conformation. GO:0010873 positive regulation of cholesterol esterification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010873 Any process that increases the frequency, rate or extent of cholesterol esterification. Cholesterol esterification is the lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and cholesterol. In the blood this process is associated with the conversion of free cholesterol into cholesteryl ester, which is then sequestered into the core of a lipoprotein particle. GO:0009884 cytokinin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009884 Combining with a cytokinin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0019207 kinase regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019207 Modulates the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule. GO:0044218 other organism cell membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044218 foreign membrane|other organism membrane The cell membrane of a secondary organism with which the first organism is interacting. GO:0010874 regulation of cholesterol efflux biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010874 Any process that modulates the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle. GO:0019208 phosphatase regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019208 Modulates the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule. GO:0044219 host cell plasmodesma biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044219 A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one host cell to that of an adjacent host cell. GO:0009885 transmembrane histidine kinase cytokinin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009885 Combining with a cytokinin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-histidine = ADP + a protein-L-histidine phosphate. GO:0044216 other organism cell biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044216 A cell of a secondary organism with which the first organism is interacting. GO:0010871 obsolete negative regulation of receptor biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010871 OBSOLETE. Any process that decreases the frequency or rate of receptor biosynthesis. Receptor biosynthesis is the collection of chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. GO:0034820 4,9-DSHA hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034820 UM-BBD_reactionID:r1152 Catalysis of the reaction: (3E,1Z)-4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate + H2O = (2E,4E)-2-hydroxyhexa-2,4-dienoate + 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oate + H+. GO:0019205 nucleobase-containing compound kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019205 nucleobase, nucleoside, nucleotide kinase activity Catalysis of the transfer of a phosphate group, usually from ATP or GTP, to a nucleobase, nucleoside, nucleotide or polynucleotide substrate. GO:0009886 post-embryonic animal morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009886 post-embryonic morphogenesis of an anatomical structure The process, occurring after animal embryonic development, by which anatomical structures are generated and organized. GO:0034821 citronellol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034821 UM-BBD_reactionID:r1155 Catalysis of the reaction: citronellol + NAD+ = citronellal + NADH + H+. GO:0010872 regulation of cholesterol esterification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010872 Any process that modulates the frequency, rate or extent of cholesterol esterification. Cholesterol esterification is the lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and cholesterol. In the blood this process is associated with the conversion of free cholesterol into cholesteryl ester, which is then sequestered into the core of a lipoprotein particle. GO:0019206 nucleoside kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019206 Reactome:R-HSA-110138|Reactome:R-HSA-109903|Reactome:R-HSA-73632|Reactome:R-HSA-110137|Reactome:R-HSA-74207|Reactome:R-HSA-73598|Reactome:R-HSA-109671|Reactome:R-HSA-73599|Reactome:R-HSA-109759 Catalysis of the reaction: ATP + nucleoside = ADP + nucleoside monophosphate. GO:0009887 animal organ morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009887 histogenesis and organogenesis Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. GO:0044217 other organism part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0044217 Any constituent part of a secondary organism with which the first organism is interacting. GO:0009888 tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009888 Wikipedia:Histogenesis histogenesis and organogenesis|histogenesis The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure. GO:0019203 carbohydrate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019203 Reactome:R-HSA-3781011|Reactome:R-HSA-3791349|Reactome:R-HSA-3781018 Catalysis of the reaction: carbohydrate phosphate + H2O = carbohydrate + phosphate. GO:0019204 obsolete nucleotide phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019204 nucleotide phosphatase activity OBSOLETE. Catalysis of the reaction: phosphopolynucleotide + H2O = polynucleotide + phosphate. GO:0009889 regulation of biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009889 regulation of anabolism|regulation of synthesis|regulation of biosynthesis|regulation of formation Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances. GO:0019201 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019201 GO:0019202 amino acid kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019202 Catalysis of the transfer of a phosphate group, usually from ATP, to an amino acid substrate. GO:0019200 carbohydrate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019200 Reactome:R-HSA-8931653 Catalysis of the transfer of a phosphate group, usually from ATP, to a carbohydrate substrate molecule. GO:0034819 3-HSA hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034819 EC:1.14.13.-|UM-BBD_reactionID:r1150 Catalysis of the reaction: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + NADPH + H+ + O2 = 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + NADP+ + H2O. GO:0010844 recombination hotspot binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010844 DNA binding, recombination hotspot Interacting selectively and non-covalently with a region in a genome which promotes recombination. GO:0034811 benzo(a)pyrene 9,10-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034811 EC:1.13.11.-|UM-BBD_reactionID:r1132 Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-9,10-dihydrodiol. GO:0044225 apical pole of neuron biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044225 NIF_Subcellular:sao1186862860 Portion of a neuron cell soma closest to the point where the apical dendrite emerges. GO:0010845 positive regulation of reciprocal meiotic recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010845 positive regulation of meiotic recombination Any process that increases the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate. GO:0034812 9,10-dihydroxybenzo(a)pyrene dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034812 EC:1.13.11.-|UM-BBD_reactionID:r1134 Catalysis of the reaction: 9,10-dihydroxybenzo(a)pyrene + O2 = cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate. GO:0044226 basal pole of neuron biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044226 NIF_Subcellular:sao1186862860 Portion of a neuron cell soma closest to the point where the basilar dendrite emerges. GO:0044223 pirellulosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044223 A cytoplasmic structure found in bacterial phyla Planctomycetes and Verrucomicrobia containing a condensed nucleoid and ribosomes and surrounded by an intracytoplasmic membrane. It is surrounded by ribosome-free cytoplasm, in a compartment called the paryphoplasm. GO:0034813 benzo(a)pyrene 7,8-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034813 EC:1.13.11.-|UM-BBD_reactionID:r1137 Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-7,8-dihydrodiol. GO:0010842 retina layer formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010842 retinal layer formation|retinal lamination The process in which the vertebrate retina is organized into three laminae: the outer nuclear layer (ONL), which contains photoreceptor nuclei; the inner nuclear layer (INL), which contains amacrine, bipolar and horizontal cells; and the retinal ganglion cell (RGC) layer. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells. The inner plexiform layer (IPL) is positioned between the INL and the ganglion cell layer and contains the dendrites of RGCs and processes of bipolar and amacrine cells. Spanning all layers of the retina are the radially oriented Mueller glia. GO:0010843 obsolete promoter binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010843 DNA binding, transcription promoter|promoter binding OBSOLETE. Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for transcription factor complexes of the basal transcription machinery. GO:0044224 juxtaparanode region of axon biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044224 NIF_Subcellular:sao758620702 juxtaparanodal region|juxtaparanode|juxta paranode axon A region of an axon near a node of Ranvier that is between the paranode and internode regions. GO:0034814 7,8-dihydroxy benzo(a)pyrene dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034814 EC:1.13.11.-|UM-BBD_reactionID:r1138 Catalysis of the reaction: benzo(a)pyrene-cis-7,8-dihydrodiol + O2 = cis-4-(7-hydroxypyren-8-yl)-2-oxobut-3-enoate. GO:0044221 host cell synapse biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044221 The junction between a nerve fiber of one host neuron and another host neuron or muscle fiber or glial cell; the site of interneuronal communication. GO:0034815 cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034815 UM-BBD_reactionID:r1135|EC:4.1.3.- Catalysis of the reaction: cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate = 10-oxabenzo(def)chrysen-9-one + formate + H+. GO:0010848 regulation of chromatin disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010848 Any process that modulates the frequency, rate or extent of chromatin disassembly. Chromatin disassembly is the controlled breakdown of chromatin from a higher order structure into its simpler subcomponents, DNA, histones, and other proteins. GO:0044222 anammoxosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044222 An intracytoplasmic membrane-bounded compartment in anaerobic ammonium oxidation (anammox) bacteria, is the site of anammox catabolism. GO:0010849 regulation of proton-transporting ATPase activity, rotational mechanism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010849 regulation of V-type ATPase activity|regulation of hydrogen ion transporting ATPase activity, rotational mechanism Any process that modulates the rate of ATP hydrolysis by an ATPase. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism. GO:0034816 anthracene 9,10-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034816 UM-BBD_reactionID:r1141 Catalysis of the reaction: anthracene + 2 H2O = cis-9,10-dihydroanthracene-9,10-diol. GO:0034817 cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034817 UM-BBD_reactionID:r1144 Catalysis of the reaction: cis-9,10-dihydroanthracene-9,10-diol = 9,10-anthraquinone + 4 H+ + 4 e-. GO:0010846 activation of reciprocal meiotic recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010846 activation of meiotic recombination Any process that starts the inactive process of reciprocal meiotic recombination. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate. GO:0044220 host cell perinuclear region of cytoplasm biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044220 The host cell cytoplasm situated near, or occurring around, the host nucleus. GO:0034818 ADD 9alpha-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034818 EC:1.14.15.-|UM-BBD_reactionID:r1149 Catalysis of the reaction: androsta-1,4-diene-3,17-dione + reduced ferredoxin + O2 = 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + H2O + oxidized ferredoxin. GO:0010847 regulation of chromatin assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010847 Any process the modulates the frequency, rate or extent of chromatin assembly. Chromatin assembly is the assembly of DNA, histone proteins, and other associated proteins into chromatin structure, beginning with the formation of the basic unit, the nucleosome, followed by organization of the nucleosomes into higher order structures, ultimately giving rise to a complex organization of specific domains within the nucleus. CHEBI:33033 2-oxopentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33033 GO:0009850 auxin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009850 auxin metabolism The chemical reactions and pathways involving auxins, a group of plant hormones that regulate aspects of plant growth. GO:0044229 host cell periplasmic space biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044229 The region between the inner (cytoplasmic) and outer host membrane (Gram-negative Bacteria) or inner host membrane and host cell wall (Fungi). GO:0010840 regulation of circadian sleep/wake cycle, wakefulness biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010840 Any process that modulates the rate, frequency, or extent of the wakeful phase of the circadian sleep/wake cycle. The wakeful phase is the part of the circadian sleep/wake cycle where the organism is not asleep. GO:0009851 auxin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009851 auxin biosynthesis|auxin anabolism|auxin synthesis|auxin formation The chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth. GO:0009852 auxin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009852 auxin breakdown|auxin catabolism|auxin degradation The chemical reactions and pathways resulting in the breakdown of auxins, a group of plant hormones that regulate aspects of plant growth. GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010841 Any process that increases the frequency, or extent of the wakeful phase of the circadian sleep/wake cycle. The wakeful phase is the part of the circadian sleep/wake cycle where the organism is not asleep. GO:0009853 photorespiration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009853 MetaCyc:PWY-181|Wikipedia:Photorespiration A light-dependent catabolic process occurring concomitantly with photosynthesis in plants (especially C3 plants) whereby dioxygen (O2) is consumed and carbon dioxide (CO2) is evolved. The substrate is glycolate formed in large quantities in chloroplasts from 2-phosphoglycolate generated from ribulose 1,5-bisphosphate by the action of ribulose-bisphosphate carboxylase; the glycolate enters the peroxisomes where it is converted by glycolate oxidase to glyoxylate which undergoes transamination to glycine. This then passes into the mitochondria where it is decarboxylated forming one molecule of serine for every two molecules of glycine. This pathway also exists in photosynthetic bacteria. GO:0044227 methane-oxidizing organelle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044227 methanotroph intracytoplasmic membrane-bound compartment|methane-oxidizing compartment A cytoplasmic, membrane-bounded compartment found within Methanotrophic bacteria that contains enzymes and electron transfer proteins for methane catabolism. This structure is analogous to the thylakoid of Cyanobacteria and the anammoxosome of anaerobic ammonium oxidation organisms. GO:0034810 4,5-dihydroxybenzo(a)pyrene dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034810 EC:1.13.11.-|UM-BBD_reactionID:r1128 Catalysis of the reaction: 4,5-dihydroxybenzo(a)pyrene + O2 = 4,5-chrysenedicarboxylate. GO:0044228 host cell surface biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044228 The external part of the host cell wall and/or host plasma membrane. GO:0009854 oxidative photosynthetic carbon pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009854 The reactions of the C2 pathway bring about the metabolic conversion of two molecules of 2-phosphoglycolate to one molecule of 3-phosphoglycerate, which can be used by the C3 cycle, and one molecule of carbon dioxide (CO2). GO:0009855 determination of bilateral symmetry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009855 determination of bilateral asymmetry The establishment of an organism's body plan or part of an organism with respect to a single longitudinal plane. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry. GO:0009856 pollination biolink:BiologicalProcess go-plus goslim_plant http://purl.obolibrary.org/obo/GO_0009856 Wikipedia:Pollination The cascade of biological processes occurring in plants beginning when the pollen lands on the female reproductive organs of a plant and continuing up to, but not including, fertilization, as defined by sperm-egg cell fusion. GO:0009857 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009857 GO:0009858 obsolete compatible pollen-pistil interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009858 compatible pollen-pistil interaction OBSOLETE. An interaction between a pollen grain and pistil that results in unimpeded growth of the pollen tube through the stigma and style. GO:0009859 pollen hydration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009859 The process in which water is taken up by pollen. GO:0034808 benzo(a)pyrene 4,5-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034808 EC:1.13.11.-|UM-BBD_reactionID:r1126 Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-4,5-dihydrodiol. GO:0034809 benzo(a)pyrene-cis-4,5-dihydrodiol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034809 UM-BBD_reactionID:r1127 Catalysis of the reaction: benzo(a)pyrene-cis-4,5-dihydrodiol = 4,5-dihydroxybenzo(a)pyrene + H2. GO:0034800 trinitrophenol dihydride denitratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034800 EC:1.7.99.-|UM-BBD_reactionID:r1067 2,4,6-trinitrophenol dihydride denitratase activity|TNP dihydride denitratase activity Catalysis of the reaction: trinitrophenol dihydride Meisenheimer complex (aci form) = 2,4-dinitrophenol hydride Meisenheimer complex + NO2. Trinitrophenol is also known as TNP and dinitrophenol is also known as DNP. GO:0010855 adenylate cyclase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010855 Decreases the activity of the enzyme that catalyzes the reaction: ATP = 3',5'-cyclic AMP + diphosphate. GO:0044236 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044236 GO:0034801 2,4-dinitrocyclohexanone hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034801 UM-BBD_reactionID:r1069 Catalysis of the reaction: 2,4-dinitrocyclohexanone + OH- = 4,6-dinitrohexanoate. GO:0044237 cellular metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044237 intermediary metabolism|cellular metabolism The chemical reactions and pathways by which individual cells transform chemical substances. GO:0010856 adenylate cyclase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010856 Increases the activity of the enzyme that catalyzes the reaction: ATP = 3',5'-cyclic AMP + diphosphate. GO:0034802 branched-chain dodecylbenzene sulfonate monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034802 EC:1.14.13.-|UM-BBD_reactionID:r1079 Catalysis of the reaction: branched-chain dodecylbenzene sulfonate + 1/2 O2 + H+ = sulfurous acid + branched-chain dodecyl-4-hydroxy-benzene + sulfite. GO:0010853 cyclase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010853 Increases the activity of an enzyme that catalyzes a ring closure reaction. GO:0044234 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044234 GO:0010854 adenylate cyclase regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010854 Modulates the activity of the enzyme that catalyzes the reaction: ATP = 3',5'-cyclic AMP + diphosphate. GO:0034803 3-hydroxy-2-naphthoate 2,3-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034803 EC:1.13.11.-|UM-BBD_reactionID:r1104 Catalysis of the reaction: 3-hydroxy-2-naphthoate + O2 = (3E)-3-[(6Z)-6-(carboxymethylene)cyclohexa-2,4-dien-1-ylidene]-2-oxopropanate. GO:0044235 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044235 GO:0034804 benzo(a)pyrene 11,12-epoxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034804 UM-BBD_reactionID:r1119|EC:1.14.99.- Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-11,12-epoxide. GO:0044232 organelle membrane contact site biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044232 interorganelle junction|MCS|inter-organelle junction A zone of apposition between the membranes of an organelle with another membrane, either another membrane of the same organelle, a membrane of another organelle, or the plasma membrane. Membrane contact sites (MCSs) are structured by bridging complexes. They are specialized for communication, including the efficient traffic of small molecules such as Ca2+ ions and lipids, as well as enzyme-substrate interactions. GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010859 Stops, prevents or reduces the activity of a calcium-dependent cysteine-type endopeptidase, any enzyme that hydrolyzes peptide bonds in polypeptides by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile in a calcium-dependent manner. GO:0044233 mitochondria-associated endoplasmic reticulum membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044233 mitochondria-associated ER membrane|mitochondria-endoplasmic reticulum (ER) contact|endoplasmic reticulum-mitochondrion membrane contact site|MAM|ER-mitochondrion membrane contact site|mitochondria-associated membrane|Mitochondria-associated Membrane A zone of apposition between endoplasmic-reticulum and mitochondrial membranes, structured by bridging complexes. These contact sites are thought to facilitate inter-organelle calcium and phospholipid exchange. GO:0034805 benzo(a)pyrene-trans-11,12-dihydrodiol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034805 UM-BBD_reactionID:r1121 Catalysis of the reaction: benzo(a)pyrene-trans-11,12-dihydrodiol = 11,12-dihydroxybenzo(a)pyrene + 2 H+ + 2 e-. GO:0010857 calcium-dependent protein kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010857 Reactome:R-HSA-8986937|Reactome:R-HSA-9005561 Calcium-dependent catalysis of the reaction: a protein + ATP = a phosphoprotein + ADP. GO:0044230 host cell envelope biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044230 An envelope that surrounds a bacterial host cell and includes the host cytoplasmic membrane and everything external, encompassing the host periplasmic space, host cell wall, and host outer membrane if present. GO:0034806 benzo(a)pyrene 11,12-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034806 EC:1.13.11.-|UM-BBD_reactionID:r1124 Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-11,12-dihydrodiol. GO:0034807 4,5-dihydroxybenzo(a)pyrene methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034807 UM-BBD_reactionID:r1131 Catalysis of the reaction: 4,5-dihydroxybenzo(a)pyrene + C1 unit = hydroxymethoxybenzo(a)pyrene. GO:0044231 host cell presynaptic membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044231 other organism presynaptic membrane|other organism pre-synaptic membrane|host cell pre-synaptic membrane A specialized area of membrane of the host axon terminal that faces the plasma membrane of the host neuron or muscle fiber with which the axon terminal establishes a synaptic junction; many host synaptic junctions exhibit structural presynaptic characteristics, such as conical, electron-dense internal protrusions, that distinguish it from the remainder of the axon plasma membrane. GO:0010858 calcium-dependent protein kinase regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010858 Modulates the activity of a calcium-dependent protein kinase, an enzyme which phosphorylates a protein in a calcium-dependent manner. GO:0009860 pollen tube growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009860 Growth of pollen via tip extension of the intine wall. GO:0009861 jasmonic acid and ethylene-dependent systemic resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009861 jasmonic acid/ethylene-dependent systemic resistance|jasmonic acid and ethene-dependent systemic resistance The jasmonic acid and ethylene (ethene) dependent process that confers broad spectrum systemic resistance to disease in response to wounding or a pathogen. GO:0009862 systemic acquired resistance, salicylic acid mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009862 systemic acquired resistance, salicylic acid mediated signalling pathway|salicylic acid mediated signaling pathway (systemic acquired resistance) The series of molecular signals mediated by salicylic acid involved in systemic acquired resistance. GO:0010851 cyclase regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010851 Modulates the activity of an enzyme that catalyzes a ring closure reaction. GO:0009863 salicylic acid mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009863 salicylic acid mediated signalling pathway|salicylic acid-mediated signaling pathway|salicylic acid mediated signal transduction A series of molecular signals mediated by salicylic acid. GO:0010852 cyclase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010852 Decreases the activity of an enzyme that catalyzes a ring closure reaction. GO:0044238 primary metabolic process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0044238 primary metabolism The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. GO:0009864 induced systemic resistance, jasmonic acid mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009864 jasmonic acid mediated signaling pathway (induced systemic resistance)|induced systemic resistance, jasmonic acid mediated signalling pathway The series of molecular signals mediated by jasmonic acid involved in induced systemic resistance. GO:0010850 regulation of blood pressure by chemoreceptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010850 regulation of blood pressure by chemoreceptor signalling pathway A series of reactions within the cell that occur as a result of a single trigger reaction or compound interacting with a chemoreceptor resulting in a modulation of the force with which blood travels through the circulatory system. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions. GO:0009865 pollen tube adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009865 The process in which the pollen tube adheres to cells of the stigma and style. GO:0044239 obsolete salivary polysaccharide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044239 salivary polysaccharide degradation|salivary polysaccharide breakdown|salivary polysaccharide catabolism OBSOLETE. The chemical reactions and pathways resulting in the breakdown of polysaccharides by salivary amylase. Salivary amylase is released by salivary glands, usually in the mouth. GO:0009866 induced systemic resistance, ethylene mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009866 induced systemic resistance, ethylene mediated signalling pathway|ethylene mediated signaling pathway (induced systemic resistance)|induced systemic resistance, ethene mediated signalling pathway|ethene mediated signaling pathway (induced systemic resistance)|induced systemic resistance, ethene mediated signaling pathway The series of molecular signals mediated by ethylene (ethene) involved in induced systemic resistance. GO:0009867 jasmonic acid mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009867 jasmonate signaling|jasmonic acid mediated signalling pathway|JA signaling A series of molecular signals mediated by jasmonic acid. GO:0009868 jasmonic acid and ethylene-dependent systemic resistance, jasmonic acid mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009868 jasmonic acid/ethene-dependent systemic resistance, jasmonic acid mediated signalling pathway|jasmonic acid/ethene-dependent systemic resistance, jasmonic acid mediated signaling pathway|jasmonic acid mediated signaling pathway (jasmonic acid/ethylene-dependent systemic resistance)|jasmonic acid and ethene-dependent systemic resistance, jasmonic acid mediated signaling pathway|jasmonic acid/ethylene-dependent systemic resistance, jasmonic acid mediated signalling pathway|jasmonic acid/ethylene-dependent systemic resistance, jasmonic acid mediated signaling pathway|jasmonic acid mediated signaling pathway (jasmonic acid/ethene-dependent systemic resistance) The series of molecular signals mediated by jasmonic acid involved in jasmonic acid/ethylene (ethene) dependent systemic resistance. GO:0009869 obsolete incompatible pollen-pistil interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009869 incompatible pollen-pistil interaction OBSOLETE. An interaction between a pollen grain and pistil that results in inhibition of pollen germination/growth. CHEBI:23696 dichloroaniline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23696 GO:0044240 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044240 CHEBI:23697 dichlorobenzene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23697 GO:0010828 positive regulation of glucose transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010828 positive regulation of glucose transport Any process that increases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0010829 negative regulation of glucose transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010829 negative regulation of glucose transport Any process that decreases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:23698 dichlorobenzoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23698 CHEBI:23699 dichlorocatechol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23699 GO:0044247 cellular polysaccharide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044247 cellular polysaccharide degradation|cellular polysaccharide breakdown|cellular polysaccharide catabolism The chemical reactions and pathways resulting in the breakdown of polysaccharides, polymers of many (typically more than 10) monosaccharide residues linked glycosidically, as carried out by individual cells. CHEBI:33019 diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33019 GO:0010822 positive regulation of mitochondrion organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010822 positive regulation of mitochondrion organisation Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion. GO:0044248 cellular catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044248 cellular catabolism|cellular degradation|cellular breakdown The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells. GO:0010823 negative regulation of mitochondrion organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010823 negative regulation of mitochondrion organisation Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion. GO:0010820 positive regulation of T cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010820 Any process that increases the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus. GO:0044245 polysaccharide digestion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044245 The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested polysaccharides into components that may be easily absorbed and directed into metabolism. GO:0044246 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044246 GO:0010821 regulation of mitochondrion organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010821 regulation of mitochondrion organisation Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion. GO:0044243 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044243 GO:0010826 negative regulation of centrosome duplication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010826 Any process that decreases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized. GO:0044244 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044244 GO:0010827 regulation of glucose transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010827 regulation of glucose transport Any process that modulates the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0044241 lipid digestion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044241 The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested lipids into components that may be easily absorbed and directed into metabolism. GO:0010824 regulation of centrosome duplication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010824 Any process that modulates the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized. CHEBI:23690 dicarboxylic acid amide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23690 GO:0044242 cellular lipid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044242 cellular lipid degradation|cellular lipid breakdown|cellular lipid catabolism The chemical reactions and pathways resulting in the breakdown of lipids, as carried out by individual cells. GO:0010825 positive regulation of centrosome duplication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010825 Any process that increases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized. PO:0008030 trichome cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0008030 毛（毛茸、糸状体）細胞 (Japanese, exact)|célula del tricoma (Spanish, exact) A plant cell (PO:0009002) that is part of a multicellular trichome (PO:0000282). GO:0009830 cell wall modification involved in abscission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009830 cell wall modification during abscission A cellular process that results in the breakdown of the cell wall that contributes to the process of abscission. GO:0009831 plant-type cell wall modification involved in multidimensional cell growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009831 cell wall modification during cell expansion|cellulose and pectin-containing cell wall modification during multidimensional cell growth The series of events that occur during cell growth that result in chemical or structural changes to existing cell walls of the type composed chiefly of cellulose and pectin. An example of this is found in Arabidopsis thaliana. CHEBI:33017 diphosphate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33017 GO:0044249 cellular biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044249 cellular biosynthesis|cellular anabolism|cellular synthesis|cellular formation The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. GO:0009832 plant-type cell wall biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009832 cell wall formation|cellulose and pectin-containing cell wall biogenesis|cell wall biosynthetic process|cell wall anabolism|cell wall assembly|cell wall synthesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellulose and pectin-containing cell wall. An example of this is found in Arabidopsis thaliana. GO:0009833 plant-type primary cell wall biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009833 primary cell wall formation|cellulose and pectin-containing primary cell wall biogenesis|primary cell wall anabolism|primary cell wall biosynthetic process|primary cell wall biogenesis|primary cell wall synthesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of cellulose and pectin-containing cell walls that form adjacent to the middle lamella following cell division and during cell expansion. An example of this is found in Arabidopsis thaliana. GO:0009834 plant-type secondary cell wall biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009834 secondary cell wall anabolism|secondary cell wall biosynthetic process|secondary cell wall synthesis|secondary cell wall biogenesis|secondary cell wall formation|cellulose and pectin-containing secondary cell wall biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of inextensible cellulose- and pectin-containing cell walls that are formed between the plasma membrane and primary cell wall after cell expansion is complete. An example of this is found in Arabidopsis thaliana. GO:0009835 fruit ripening biolink:BiologicalProcess go-plus goslim_plant http://purl.obolibrary.org/obo/GO_0009835 Wikipedia:Ripening fruit senescence|fruit maturation An aging process that has as participant a fruit. Ripening causes changes in one or more characteristics of a fruit (color, aroma, flavor, texture, hardness, cell wall structure) and may make it more attractive to animals and aid in seed dispersal. GO:0009836 fruit ripening, climacteric biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009836 A fruit ripening process that involves a burst of respiration and ethylene (ethene) evolution at the onset. GO:0009837 fruit ripening, non-climacteric biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009837 A fruit ripening process that does not involve a respiratory burst. GO:0009838 abscission biolink:BiologicalProcess go-plus goslim_plant http://purl.obolibrary.org/obo/GO_0009838 Wikipedia:Abscission The controlled shedding of a body part. GO:0009839 obsolete SCF complex substrate recognition subunit biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009839 SCF complex substrate recognition subunit OBSOLETE. The portion of the SCF ubiquitin ligase complex that contains sites required for recognition (and recruitment) of the substrate to the complex. CHEBI:33010 chromide(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33010 GO:0044250 negative regulation of metabolic activity involved in hibernation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044250 down regulation of metabolic activity during hibernation|downregulation of metabolic activity during hibernation|negative regulation of metabolic activity during hibernation|down-regulation of metabolic activity during hibernation|inhibition of metabolic activity during hibernation The slowing of metabolic processes to very low levels in order to conserve energy as a part of hibernation. GO:0044251 obsolete protein catabolic process by pepsin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044251 protein degradation by pepsin|protein breakdown by pepsin OBSOLETE. The chemical reactions and pathways resulting in the breakdown of a protein by pepsin in the stomach. Pepsin is generated from its precursor pepsinogen, which is activated by hydrolchloric acid (gastric acid). GO:0010839 negative regulation of keratinocyte proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010839 Any process that decreases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. GO:0044258 intestinal lipid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044258 intestinal lipid breakdown|intestinal lipid degradation|intestinal lipid catabolism The chemical reactions and pathways resulting in the breakdown into fatty acids and monoglycerides of lipids in the small intestine. Lipids are broken down by lipases released by the pancreas. GO:0010833 telomere maintenance via telomere lengthening biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010833 Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins and lengthening the telomeric DNA. GO:0044259 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044259 GO:0010834 obsolete telomere maintenance via telomere shortening biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010834 telomere maintenance via telomere shortening OBSOLETE. Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins and shortening the telomeric DNA. GO:0044256 protein digestion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044256 The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested proteins into components that may be easily absorbed and directed into metabolism. GO:0010831 positive regulation of myotube differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010831 Any process that activates, maintains or increases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. GO:0010832 negative regulation of myotube differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010832 Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. GO:0044257 cellular protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044257 cellular protein degradation|cellular protein breakdown|cellular protein catabolism The chemical reactions and pathways resulting in the breakdown of a protein by individual cells. GO:0044254 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044254 GO:0010837 regulation of keratinocyte proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010837 Any process that modulates the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. GO:0044255 cellular lipid metabolic process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0044255 cellular lipid metabolism The chemical reactions and pathways involving lipids, as carried out by individual cells. GO:0010838 positive regulation of keratinocyte proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010838 Any process that increases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. GO:0010835 regulation of protein ADP-ribosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010835 regulation of protein amino acid ADP-ribosylation Any process that modulates the frequency, rate or extent of protein ADP-ribosylation. Protein ADP-ribosylation is the transfer, from NAD, of ADP-ribose to protein amino acids. GO:0044252 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044252 GO:0010836 negative regulation of protein ADP-ribosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010836 negative regulation of protein amino acid ADP-ribosylation Any process that decreases the frequency, rate or extent of protein ADP-ribosylation. Protein ADP-ribosylation is the transfer, from NAD, of ADP-ribose to protein amino acids. GO:0044253 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044253 GO:0009840 chloroplastic endopeptidase Clp complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009840 A Clp endopeptidase complex located in the chloroplast. GO:0010830 regulation of myotube differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010830 Any process that modulates the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. GO:0009841 mitochondrial endopeptidase Clp complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009841 A Clp endopeptidase complex located in the mitochondrion. GO:0009842 cyanelle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009842 muroplast|cyanoplast A plastid that contains unstacked, phycobilisome-bearing thylakoid membranes and is surrounded by a double membrane with a peptidoglycan layer in the intermembrane space between the two envelope membranes. Cyanelles are characteristic of algae in the class Glaucophyta, and may represent an ancestral form of plastid. GO:0009843 cyanelle thylakoid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009843 A thylakoid found in a cyanelle, which is a type of plastid found in certain algae. The cyanelle contains a photosynthetic membrane resembling that of cyanobacteria. GO:0009844 obsolete germination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009844 germination OBSOLETE. The physiological and developmental changes by a seed, spore, pollen grain (microspore), or zygote that occur after release from dormancy, and encompassing events prior to and including the first visible indications of growth. GO:0009845 seed germination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009845 Wikipedia:Germination#Seed_germination The physiological and developmental changes that occur in a seed commencing with water uptake (imbibition) and terminating with the elongation of the embryonic axis. GO:0009846 pollen germination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009846 The physiological and developmental changes that occur in a heterosporous plant pollen grain, beginning with hydration and terminating with the emergence of the pollen tube through the aperture. PO:0008028 reproductive shoot apical meristem biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0008028 生殖シュート頂端 分裂組織 (Japanese, exact)|meristema apical reproductivo del epiblasto (epiblastema) (Spanish, exact) A shoot apical meristem (PO:0020148) that gives rise to the apical growth of reproductive tissues and organs. GO:0009847 spore germination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009847 spore germination on or near host The physiological and developmental changes that occur in a spore following release from dormancy up to the earliest signs of growth (e.g. emergence from a spore wall). GO:0009848 indoleacetic acid biosynthetic process via tryptophan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009848 MetaCyc:PWY-581 indoleacetic acid formation via tryptophan|indoleacetic acid synthesis via tryptophan|indoleacetic acid anabolism via tryptophan|IAA biosynthetic process via tryptophan The chemical reactions and pathways resulting in the formation of indole-3-acetic acid that occurs through metabolism of L-tryptophan. GO:0009849 tryptophan-independent indoleacetic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009849 MetaCyc:PWY-581 tryptophan-independent indoleacetic acid biosynthesis|tryptophan-independent IAA biosynthetic process|tryptophan-independent indoleacetic acid synthesis|tryptophan-independent indoleacetic acid formation|indoleacetic acid biosynthetic process, tryptophan-independent|indoleacetic acid biosynthesis, tryptophan-independent|tryptophan-independent indoleacetic acid anabolism The chemical reactions and pathways resulting in the formation of indoleacetic acid, independent of tryptophan. CHEBI:33020 kojibiose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33020 CHEBI:139160 1-(4-methoxyphenyl)-N-methyl-N-[(3-methyloxetan-3-yl)methyl]methanamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139160 CHEBI:139161 1-(4-methoxyphenyl)-N-methyl-N-[(3-methyloxetan-3-yl)methyl]methanamine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139161 CHEBI:139162 oleuropein aglycone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139162 CHEBI:139163 2-{[(4-methoxybenzyl)(methyl)amino]methyl}-2-methylpropane-1,3-diol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139163 CHEBI:72600 spiroketal biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72600 CHEBI:140157 8-carboxy-8-demethylriboflavin 5'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_140157 CHEBI:72606 11-HETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72606 CHEBI:72608 (4Z,7Z,10Z,14E,16Z,19Z)-13-hydroxydocosahexaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72608 CHEBI:140156 8-formyl-8-demethylriboflavin 5'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_140156 CHEBI:140153 (9Z,12R)-12-hydroxyoctadec-9-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_140153 CHEBI:140159 D-hexose phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140159 CHEBI:139157 (S,S)-2-oleoylglycero-1-phospho-1'-glycerol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139157 CHEBI:139158 [(1->2)-alpha-L-rhamnosyl-(1->4)-alpha-D-galacturonosyl]n polyanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139158 CHEBI:139159 alpha-D-galacturonosyl-[(1->2)-alpha-L-rhamnosyl-(1->4)-alpha-D-galacturonosyl]n polyanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139159 GO:0019298 coenzyme B biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019298 MetaCyc:P241-PWY coenzyme B anabolism|coenzyme B synthesis|coenzyme B formation|coenzyme B biosynthesis The chemical reactions and pathways resulting in the formation of coenzyme B (7-mercaptoheptanoylthreonine phosphate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes. CHEBI:139154 AZD1979 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139154 GO:0019299 rhamnose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019299 rhamnose metabolism The chemical reactions and pathways involving rhamnose, the hexose 6-deoxy-L-mannose. Rhamnose occurs commonly as a compound of plant glycosides, in polysaccharides of gums and mucilages, and in bacterial polysaccharides. It is also a component of some plant cell wall polysaccharides and frequently acts as the sugar components of flavonoids. GO:0019296 coenzyme M metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019296 coenzyme M metabolism The chemical reactions and pathways involving coenzyme M (2-thioethansulfonate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes. CHEBI:139155 melanin-concentrating hormone receptor antagonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139155 CHEBI:139156 (S,S)-bis-(2-oleoylglycero)-1-phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139156 GO:0019297 coenzyme B metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019297 coenzyme B metabolism The chemical reactions and pathways involving coenzyme B (7-mercaptoheptanoylthreonine phosphate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes. CHEBI:139171 N(2)-[(3R)-3-(2-hydroxyacyloxy)acyl]-L-ornithine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139171 CHEBI:139164 2-{[(4-methoxybenzyl)(methyl)amino]methyl}-2-methylpropane-1,3-diol(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139164 CHEBI:139166 secoiridoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139166 GO:0019283 L-methionine biosynthetic process from O-phospho-L-homoserine and cystathionine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019283 L-methionine anabolism from O-phospho-L-homoserine and cystathionine|L-methionine synthesis from O-phospho-L-homoserine and cystathionine|L-methionine formation from O-phospho-L-homoserine and cystathionine|methionine biosynthetic process from O-phospho-L-homoserine and cystathionine The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including O-phospho-L-homoserine and cystathionine. GO:0019284 L-methionine salvage from S-adenosylmethionine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019284 L-methionine synthesis from S-adenosylmethionine|L-methionine formation from S-adenosylmethionine The chemical reactions and pathways resulting in the formation of L-methionine from S-adenosylmethionine. GO:0019281 L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019281 MetaCyc:MET-SAM-PWY L-methionine anabolism from homoserine via O-succinyl-L-homoserine and cystathionine|L-methionine synthesis from homoserine via O-succinyl-L-homoserine and cystathionine|L-methionine formation from homoserine via O-succinyl-L-homoserine and cystathionine|methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including homoserine, via the intermediates O-succinyl-L-homoserine and cystathionine. GO:0019282 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019282 GO:0103100 UDP-glucose: 6-methylthiohexylhydroximate S-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103100 EC:2.4.1.195|MetaCyc:RXNQT-4325 Catalysis of the reaction: UDP-alpha-D-glucose + 6-methylthiohexylhydroximate <=> H+ + 5-methylthiopentyldesulfoglucosinolate + UDP(3-). GO:0103101 UDP-glucose:7-methylthioheptylhydroximate S-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103101 EC:2.4.1.195|MetaCyc:RXNQT-4326 Catalysis of the reaction: UDP-alpha-D-glucose + 7-methylthioheptylhydroximate <=> H+ + 6-methylthiohexyldesulfoglucosinolate + UDP. GO:0019280 L-methionine biosynthetic process from homoserine via O-acetyl-L-homoserine and cystathionine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019280 MetaCyc:HSERMETANA-PWY methionine biosynthetic process from homoserine via O-acetyl-L-homoserine and cystathionine|L-methionine anabolism from homoserine via O-acetyl-L-homoserine and cystathionine|L-methionine synthesis from homoserine via O-acetyl-L-homoserine and cystathionine|L-methionine formation from homoserine via O-acetyl-L-homoserine and cystathionine The chemical reactions and pathways resulting in the formation of methionine from other compounds, including homoserine, via the intermediates O-acetyl-L-homoserine and cystathionine. GO:0103104 6-methylthiohexyldesulfoglucosinolate sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103104 MetaCyc:RXNQT-4331 Catalysis of the reaction: 6-methylthiohexyldesulfoglucosinolate + 3'-phosphonato-5'-adenylyl sulfate <=> adenosine 3',5'-bismonophosphate + H+ + 6-methylthiohexylglucosinolate. CHEBI:140135 8-amino-8-demethylriboflavin 5'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_140135 CHEBI:72627 15-HEPE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72627 GO:0103105 2-oxo-6-methylthiohexanoate aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103105 MetaCyc:RXNQT-4345 Catalysis of the reaction: 2-oxo-6-methylthiohexanoate + a standard alpha amino acid <=> dihomomethionine + a 2-oxo carboxylate. GO:0103102 UDP-glucose:8-methylthiooctylhydroximate S-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103102 EC:2.4.1.195|MetaCyc:RXNQT-4327 Catalysis of the reaction: UDP-alpha-D-glucose + 8-methylthiooctylhydroximate <=> H+ + 7-methylthioheptyldesulfoglucosinolate + UDP. GO:0103103 UDP-glucose: 9-methylthiononylhydroximate S-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103103 EC:2.4.1.195|MetaCyc:RXNQT-4328 Catalysis of the reaction: UDP-alpha-D-glucose + 9-methylthiononylhydroximate <=> 8-methylthiooctyldesulfoglucosinolate + UDP + H+. GO:0103106 brassinolide 23-O-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103106 MetaCyc:RXNQT-4397 Catalysis of the reaction: brassinolide + UDP-alpha-D-glucose <=> brassinolide-23-O-glucoside + UDP + H+. GO:0103107 castasterone 23-O-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103107 MetaCyc:RXNQT-4398 Catalysis of the reaction: castasterone + UDP-alpha-D-glucose <=> castasterone-23-O-glucoside + UDP + H+. GO:0019278 UDP-N-acetylgalactosamine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019278 UDP-N-acetylgalactosamine catabolism|UDP-N-acetylgalactosamine degradation|UDP-N-acetylgalactosamine breakdown The chemical reactions and pathways resulting in the breakdown of UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate. GO:0019279 L-methionine biosynthetic process from L-homoserine via cystathionine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019279 MetaCyc:HOMOSER-METSYN-PWY methionine biosynthetic process from L-homoserine via cystathionine|L-methionine anabolism from L-homoserine via cystathionine|L-methionine synthesis from L-homoserine via cystathionine|L-methionine formation from L-homoserine via cystathionine The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including L-homoserine, via the intermediate cystathionine. GO:0019276 UDP-N-acetylgalactosamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019276 UDP-N-acetylgalactosamine metabolism The chemical reactions and pathways involving UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate. GO:0019277 UDP-N-acetylgalactosamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019277 MetaCyc:UDPNACETYLGALSYN-PWY UDP-N-acetylgalactosamine biosynthesis|UDP-N-acetylgalactosamine anabolism|UDP-N-acetylgalactosamine synthesis|UDP-N-acetylgalactosamine formation The chemical reactions and pathways resulting in the formation of UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate. GO:0019274 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019274 GO:0019275 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019275 GO:0019294 keto-3-deoxy-D-manno-octulosonic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019294 MetaCyc:KDOSYN-PWY keto-3-deoxy-D-manno-octulosonic acid synthesis|keto-3-deoxy-D-manno-octulosonic acid formation|ketodeoxyoctanoate biosynthetic process|keto-3-deoxy-D-manno-octulosonic acid biosynthesis|KDO biosynthetic process|KDO biosynthesis|keto-3-deoxy-D-manno-octulosonic acid anabolism The chemical reactions and pathways resulting in the formation of keto-3-deoxy-D-manno-octulosonic acid, an acidic sugar present in lipopolysaccharides of the outer membranes of some Gram-negative bacteria. GO:0019295 coenzyme M biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019295 MetaCyc:P261-PWY coenzyme M formation|coenzyme M biosynthesis|coenzyme M anabolism|coenzyme M synthesis The chemical reactions and pathways resulting in the formation of coenzyme M (2-thioethansulfonate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes. CHEBI:139150 (S,S)-bis-(3-oleoylglycero)-1-phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139150 CHEBI:139151 ADP-5-ethyl-4-methylthiazole-2-carboxylate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139151 GO:0019292 tyrosine biosynthetic process from chorismate via 4-hydroxyphenylpyruvate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019292 MetaCyc:TYRSYN tyrosine biosynthetic process from chorismate via p-hydroxyphenylpyruvate|tyrosine anabolism from chorismate via 4-hydroxyphenylpyruvate|tyrosine synthesis from chorismate via 4-hydroxyphenylpyruvate|tyrosine formation from chorismate via 4-hydroxyphenylpyruvate The chemical reactions and pathways resulting in the formation of tyrosine from other compounds, including chorismate, via the intermediate 4-hydroxyphenylpyruvate. GO:0019293 tyrosine biosynthetic process, by oxidation of phenylalanine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019293 tyrosine anabolism, by oxidation of phenylalanine|tyrosine anabolism from chorismate via L-phenylalanine|tyrosine synthesis from chorismate via L-phenylalanine|tyrosine formation, by oxidation of phenylalanine|tyrosine formation from chorismate via L-phenylalanine|tyrosine synthesis, by oxidation of phenylalanine|tyrosine biosynthetic process from chorismate via L-phenylalanine The chemical reactions and pathways resulting in the formation of tyrosine by the oxidation of phenylalanine. CHEBI:139152 (S,S)-3-oleoylglycero-1-phospho-1'-glycerol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139152 GO:0019290 siderophore biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019290 siderophore formation|siderochrome biosynthesis|siderochrome biosynthetic process|siderophore biosynthetic process, peptide formation|siderophore biosynthetic process, peptide modification|siderophore biosynthesis|siderophore anabolism|siderophore synthesis The chemical reactions and pathways resulting in the formation of siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action. GO:0103111 D-glucosamine PTS permease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103111 EC:2.7.1.69|MetaCyc:TRANS-RXN-167A|RHEA:37359 Catalysis of the reaction: a [PTS enzyme I]-Npi-phospho-L-histidine + D-glucosamine <=> D-glucosamine 6-phosphate + a [PTS enzyme I]-L-histidine. GO:0019291 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019291 CHEBI:72637 (4Z,7Z,10Z,13Z,15E,19Z)-17-hydroxydocosahexaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72637 GO:0103115 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0103115 GO:0103116 ABC-type D-galactofuranose transporter biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103116 MetaCyc:TRANS-RXN0-491|RHEA:61716|EC:7.5.2.9 ATP-dependent alpha-D-galactofuranose transporter activity|ATPase-coupled alpha-D-galactofuranose transporter activity|alpha-D-galactofuranose transporter activity Catalysis of the reaction: alpha-D-galactofuranose + ATP + H2O <=> alpha-D-galactofuranose + hydrogenphosphate + ADP + H+. CHEBI:72639 13-HODE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72639 GO:0103113 obsolete glucosyl-oleandomycin-exporting ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103113 MetaCyc:TRANS-RXN-220 OBSOLETE. Catalysis of the reaction: glucosyl-oleandomycin + ATP + H2O <=> glucosyl-oleandomycin + ADP + hydrogenphosphate + H+. GO:0103117 UDP-3-O-acyl-N-acetylglucosamine deacetylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103117 MetaCyc:UDPACYLGLCNACDEACETYL-RXN|RHEA:25209|EC:3.5.1.108 Catalysis of the reaction: UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-N-acetylglucosamine(2-) + H2O <=> UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine(1-) + acetate. GO:0103118 UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103118 EC:2.3.1.191|MetaCyc:UDPHYDROXYMYRGLUCOSAMNACETYLTRANS-RXN|RHEA:17817 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity Catalysis of the reaction: UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine(1-) + an (3R)-3-hydroxymyristoyl-[acp] <=> UDP-2,3-bis[O-(3R)-3-hydroxymyristoyl]-alpha-D-glucosamine + H+ + a holo-[acyl-carrier protein]. CHEBI:139146 4-O-({poly[2-N-acetyl-beta-D-glucosaminyl-1-D-ribitylphosphonato]}-di{[2R]-1-glycerylphosphonato})-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl ditrans,octacis-undecaprenyl diphosphate polyanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139146 CHEBI:139147 mannose-1D-myo-inositol 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139147 GO:0019289 rhizobactin 1021 biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019289 MetaCyc:PWY-761 rhizobactin 1021 anabolism|rhizobactin 1021 synthesis|rhizobactin 1021 formation|rhizobactin 1021 biosynthetic process, peptide modification|rhizobactin 1021 biosynthesis|rhizobactin 1021 biosynthetic process, peptide formation The chemical reactions and pathways resulting in the formation of rhizobactin 1021, (E)-4-((3-(acetylhydroxyamino)propyl)-amino)-2-hydroxy-(2-(2-(3-(hydroxy(1-oxo-2-decenyl)amino)propyl)amino)-2-oxoethyl)-4-oxobutanoic acid, a siderophore produced by Sinorhizobium meliloti. CHEBI:139148 mannose-(1D-myo-inositol 1-phosphate)2(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139148 CHEBI:139149 4-O-[poly(2-beta-D-glucosyl-1-D-ribitylphosphonato)-1-D-ribitylphosphonato-(2R)-1-glycerylphosphonato]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl ditrans,octacis-undecaprenyl diphosphate polyanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139149 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019287 isopentenyl diphosphate biosynthetic process via mevalonate|isopentenyl diphosphate anabolism, mevalonate pathway|acetate-mevalonate pathway|isopentenyl diphosphate synthesis, mevalonate pathway|isopentenyl diphosphate formation, mevalonate pathway|Ac-MVA pathway The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, via the intermediate mevalonate. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl diphosphate (IPP), the fundamental unit in isoprenoid biosynthesis, through a series of mevalonate intermediates. GO:0019288 isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019288 MetaCyc:NONMEVIPP-PWY isopentenyl diphosphate formation, mevalonate-independent pathway|isopentenyl diphosphate biosynthetic process, MEP pathway|isopentenyl diphosphate biosynthetic process via 1-deoxy-D-xylulose 5-phosphate|isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway|isopentenyl diphosphate biosynthetic process, mevalonate-independent|isopentenyl diphosphate anabolism, mevalonate-independent pathway|isopentenyl diphosphate biosynthesis, mevalonate-independent|non-MVA pathway|mevalonate-independent isopentenyl diphosphate biosynthetic process|mevalonate-independent isopentenyl diphosphate biosynthesis|isopentenyl diphosphate biosynthetic process, non-mevalonate pathway|isopentenyl diphosphate biosynthesis, non-mevalonate pathway|isopentenyl diphosphate synthesis, mevalonate-independent pathway The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate-independent pathway. Isopentenyl diphosphate (IPP) is the fundamental unit in isoprenoid biosynthesis and is biosynthesized from pyruvate and glyceraldehyde 3-phosphate via intermediates, including 1-deoxy-D-xylulose 5-phosphate. GO:0019285 glycine betaine biosynthetic process from choline biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019285 MetaCyc:P542-PWY|MetaCyc:BETSYN-PWY|MetaCyc:CHOLINE-BETAINE-ANA-PWY glycine betaine formation from choline|glycine betaine synthesis from choline|glycine betaine anabolism from choline|choline oxidation|N-trimethylglycine biosynthetic process from choline|N-trimethylglycine biosynthesis from choline The chemical reactions and pathways resulting in the formation of betaine (N-trimethylglycine) from the oxidation of choline. GO:0019286 glycine betaine biosynthetic process from glycine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019286 MetaCyc:P541-PWY N-trimethylglycine biosynthetic process from glycine|N-trimethylglycine biosynthesis from glycine|glycine betaine formation from glycine|glycine betaine synthesis from glycine|glycine betaine anabolism from glycine The chemical reactions and pathways resulting in the formation of glycine betaine from other compounds, including glycine. CHEBI:139145 4-O-({poly[2-N-acetyl-alpha-D-glucosaminyl-1-D-ribitylphosphonato]}-di{[2R]-1-glycerylphosphonato})-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl ditrans,octacis-undecaprenyl diphosphate polyanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139145 GO:0019261 1,4-dichlorobenzene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019261 MetaCyc:14DICHLORBENZDEG-PWY 1,4-dichlorobenzene degradation|1,4-dichlorobenzene breakdown|1,4-dichlorobenzene catabolism The chemical reactions and pathways resulting in the breakdown of 1,4-dichlorobenzene (p-dichlorobenzene or paramoth), a derivative of benzene with two chlorine atoms attached at opposite positions on the ring. GO:0019262 N-acetylneuraminate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019262 MetaCyc:P441-PWY N-acetylneuraminate degradation|N-acetylneuraminate breakdown|N-acetylneuraminate catabolism The chemical reactions and pathways resulting in the breakdown of N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid. CHEBI:72643 8-HETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72643 GO:0019260 1,2-dichloroethane catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019260 MetaCyc:12DICHLORETHDEG-PWY 1,2-dichloroethane catabolism|1,2-dichloroethane degradation|1,2-dichloroethane breakdown The chemical reactions and pathways resulting in the breakdown of 1,2-dichloroethane, a major commodity chemical used, for example, in the manufacture of vinyl chloride. CHEBI:72646 (3R,4R)-7,2'-dihydroxy-4'-methoxyisoflavanol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72646 CHEBI:72647 14-HDoHE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72647 CHEBI:72648 (3R)-7,2'-dihydroxy-4'-methoxyisoflavanol 4-oxonium cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72648 GO:0034899 trimethylamine monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034899 EC:1.14.13.148|UM-BBD_reactionID:r1407|RHEA:31979|KEGG_REACTION:R05623 Catalysis of the reaction: N,N,N-trimethylamine + NADPH + H+ + O2 = N,N,N-trimethylamine N-oxide + NADP+ + H2O. CHEBI:72649 cyanidin 3-O-[6-O-(4-O-beta-D-glucosyl-p-coumaroyl)-2-O-(2-O-sinapoyl-beta-D-xylosyl)-beta-D-glucosyl]-5-O-(6-O-malonyl-beta-D-glucoside)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72649 GO:0034891 endosulfan diol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034891 UM-BBD_reactionID:r1388 Catalysis of the reaction: endosulfan diol = endosulfan hydroxyether + 2 H+ + 2 e-. GO:0034892 endosulfan lactone lactonase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034892 UM-BBD_reactionID:r1389 Catalysis of the reaction: endosulfan lactone + H2O = endosulfan hydroxycarboxylate + H+. GO:0034893 N-nitrodimethylamine hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034893 UM-BBD_reactionID:r1395 Catalysis of the reaction: N-nitrodimethylamine + O2 + 2 H+ + 2 e- = N-nitromethylamine + formaldehyde + H2O. GO:0034894 4-hydroxypyridine-3-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034894 EC:1.14.13.-|UM-BBD_reactionID:r1397 Catalysis of the reaction: 4-hydroxypyridine + O2 + H+ + NADPH = pyridine-3,4-diol + H2O + NADP+. GO:0034895 pyridine-3,4-diol dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034895 EC:1.13.11.-|UM-BBD_reactionID:r1398 Catalysis of the reaction: pryidine-3,4-diol + O2 = 3-(N-formyl)-formiminopyruvate. PR:000008534 hepatocyte growth factor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000008534 HPTA|HGF|hepatopoeitin-A|SF|scatter factor A protein that is a translation product of the human HGF gene or a 1:1 ortholog thereof. GO:0034896 3-formiminopyruvate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034896 UM-BBD_reactionID:r1400|EC:3.5.99.- Catalysis of the reaction: 3-formiminopyruvate + H2O = 3-formylpyruvate + HN3. GO:0034897 4-(1-ethyl-1,4-dimethyl-pentyl)phenol monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034897 UM-BBD_reactionID:r1358 Catalysis of the reaction: 4-(1-ethyl-1,4-dimethyl-pentyl)phenol + O2 + 2 H+ + 2 e- = hydroquinone + 3,6-dimethylheptan-3-ol. GO:0034898 hexadecyltrimethylammonium chloride monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034898 UM-BBD_reactionID:r1373|EC:1.13.12.- Catalysis of the reaction: hexadecyltrimethylammonium chloride + NAD(P)H + H+ + O2 = trimethylamine + hexadecanal + NAD(P)+ + H2O. GO:0019258 4-nitrotoluene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019258 MetaCyc:P421-PWY 4-nitrotoluene degradation|4-nitrotoluene breakdown|4NT catabolic process|4NT catabolism|4-nitrotoluene catabolism The chemical reactions and pathways resulting in the breakdown of 4-nitrotoluene, 1-methyl-4-nitrobenzene. GO:0019259 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019259 CHEBI:139114 carotenoid psi-end group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139114 GO:0019256 acrylonitrile catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019256 MetaCyc:P344-PWY acrylonitrile catabolism|acrylonitrile degradation|acrylonitrile breakdown The chemical reactions and pathways resulting in the breakdown of acrylonitrile, a colorless, volatile liquid with a pungent odor. Acrylonitrile is used in the production of acrylic fibers, plastics, and synthetic rubbers. CHEBI:139115 carotenoid epsilon-end group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139115 GO:0019257 4-nitrotoluene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019257 4NT metabolism|4-nitrotoluene metabolism|4NT metabolic process The chemical reactions and pathways involving 4-nitrotoluene, 1-methyl-4-nitrobenzene. It is a light yellow liquid with a weak aromatic odor. GO:0019254 carnitine metabolic process, CoA-linked biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019254 MetaCyc:CARNMET-PWY carnitine metabolism, CoA-linked The chemical reactions and pathways involving carnitine, where metabolism is linked to CoA. GO:0019255 glucose 1-phosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019255 MetaCyc:GLUCOSE1PMETAB-PWY glucose 1-phosphate utilization|glucose 1-phosphate metabolism The chemical reactions and pathways involving glucose 1-phosphate, a monophosphorylated derivative of glucose with the phosphate group attached to C-1. CHEBI:139110 (R,R)-3-(3-hydroxydecanoyloxy)decanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139110 GO:0019252 starch biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019252 MetaCyc:PWY-622 starch anabolism|starch synthesis|starch formation|starch biosynthesis The chemical reactions and pathways resulting in the formation of starch, the most important reserve polysaccharide in plants. GO:0019253 reductive pentose-phosphate cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019253 MetaCyc:CALVIN-PWY Calvin cycle|C3 photosynthesis The fixation of carbon dioxide (CO2) as glucose in the chloroplasts of C3 plants; uses ATP and NADPH formed in the light reactions of photosynthesis; carbon dioxide reacts with ribulose 1,5-bisphosphate (catalyzed by the function of ribulose-bisphosphate carboxylase) to yield two molecules of 3-phosphoglycerate; these are then phosphorylated by ATP to 1,3-bisphosphateglyceraldehyde which, in turn, is then reduced by NADPH to glyceraldehyde 3-phosphate. The glyceraldehyde 3-phosphate is converted to fructose 5-phosphate and ribulose 5-phosphate by aldolase and other enzymes; the ribulose 5-phosphate is phosphorylated by ATP to ribulose 1,5-bisphosphate. GO:0034890 endosulfan diol hydrolyase (cyclizing) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034890 UM-BBD_reactionID:r1386 Catalysis of the reaction: endosulfan diol = endosulfan ether + H2O. GO:0019272 L-alanine biosynthetic process from pyruvate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019272 MetaCyc:ALANINE-SYN2-PWY|MetaCyc:ALANINE-VALINESYN-PWY L-alanine anabolism from pyruvate|L-alanine synthesis from pyruvate|L-alanine formation from pyruvate The chemical reactions and pathways resulting in the formation of alanine from other compounds, including pyruvate. CHEBI:72653 (4Z,7Z,10Z,13Z,16Z)-19,20-epoxydocosapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72653 GO:0019273 L-alanine biosynthetic process via ornithine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019273 L-alanine anabolism via ornithine|L-alanine synthesis via ornithine|L-alanine formation via ornithine The chemical reactions and pathways resulting in the formation of L-alanine, via the intermediate ornithine. GO:0019270 aerobactin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019270 MetaCyc:AEROBACTINSYN-PWY aerobactin synthesis|aerobactin formation|aerobactin biosynthesis|aerobactin anabolism The chemical reactions and pathways resulting in the formation of aerobactin (C22H36N4O13), a hydroxamate iron transport compound. It is a conjugate of 6-(N-acetyl-N-hydroxylamine)-2-aminohexanoic acid and citric acid. CHEBI:72654 epoxydocosapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72654 CHEBI:139130 carotenoid chi-end group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139130 GO:0019271 aerobactin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019271 The directed movement of the hydroxamate iron transport compound aerobactin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aerobactin (C22H36N4O13) is a conjugate of 6-(N-acetyl-N-hydroxylamine)-2-aminohexanoic acid and citric acid. CHEBI:72659 epoxyoctadecenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72659 GO:0034888 endosulfan monooxygenase I activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034888 UM-BBD_reactionID:r1382 Catalysis of the reaction: endosulfan + O2 + 2 H+ + 2 e- = endosulfan sulfate + H2O. GO:0034889 endosulfan hemisulfate sulfatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034889 UM-BBD_reactionID:r1384 Catalysis of the reaction: endosulfan hemisulfate + H2O = endosulfan monoalcohol + 2 H+ + sulfate. GO:0034880 citrazinate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034880 UM-BBD_reactionID:r1339 Catalysis of the reaction: citrazinate + H2O = 2,3,6-trihydroxyisonicotinate + 2 H+ + 2 e-. GO:0034881 citrazinate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034881 UM-BBD_reactionID:r1343 Catalysis of the reaction: citrazinate + H2O = cis-aconitamide. GO:0034882 cis-aconitamide amidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034882 UM-BBD_reactionID:r1344 Catalysis of the reaction: cis-aconitamide + H2O = cis-aconitate + HN3. GO:0034883 obsolete isonicotinate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034883 isonicotinate reductase activity OBSOLETE. Catalysis of the reaction: isonicotinate + 2 H+ + 2 e- = 1,4-dihydroisonicotinate. GO:0034884 obsolete gamma-N-formylaminovinylacetaldehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034884 gamma-N-formylaminovinylacetaldehyde dehydrogenase activity OBSOLETE. Catalysis of the reaction: gamma-N-formylaminovinylacetaldehyde + H2O = gamma-N-formylaminovinylacetate + 2 H+ + 2 e-. CHEBI:139129 carotenoid phi-end group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139129 GO:0034885 gamma-N-formylaminovinylacetate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034885 UM-BBD_reactionID:r1350 Catalysis of the reaction: gamma-N-formylaminovinylacetate + H2O = gamma-aminovinylacetate + HCOOH. GO:0034886 gamma-aminovinylacetate deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034886 EC:3.5.99.-|UM-BBD_reactionID:r1351 Catalysis of the reaction: gamma-aminovinylacetate + H2O = succinic semialdehyde + NH3. GO:0034887 obsolete 1,4-dihydroisonicotinate 2,3-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034887 1,4-dihydroisonicotinate 2,3-dioxygenase activity OBSOLETE. Catalysis of the reaction: 1,4-dihydroisonicotinate + O2 = gamma-N-formylaminovinylacetaldehyde + CO2. GO:0019269 obsolete glutamate biosynthetic process, using glutamate synthase (NADPH) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019269 glutamate formation, using glutamate synthase (NADPH)|glutamate biosynthetic process, using glutamate synthase (NADPH)|glutamate anabolism, using glutamate synthase (NADPH)|glutamate synthesis, using glutamate synthase (NADPH) OBSOLETE. The chemical reactions and pathways resulting in the formation of glutamate, catalyzed by the enzyme glutamate synthase (NADPH). CHEBI:139124 (3R)-1,2-didehydro-3-hydroxy-2,3-dihydrotabersonine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139124 GO:0019267 asparagine biosynthetic process from cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019267 MetaCyc:ASPSYNII-PWY asparagine anabolism from cysteine|asparagine synthesis from cysteine|asparagine formation from cysteine The chemical reactions and pathways resulting in the formation of asparagine from other compounds, including cysteine. CHEBI:139126 C-terminal S-carbamoyl-L-cysteinate residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139126 GO:0019268 obsolete glutamate biosynthetic process, using glutamate dehydrogenase (NAD(P)+) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019268 glutamate anabolism, using glutamate dehydrogenase (NAD(P)+)|glutamate biosynthetic process, using glutamate dehydrogenase (NAD(P)+)|glutamate formation, using glutamate dehydrogenase (NAD(P)+)|glutamate synthesis, using glutamate dehydrogenase (NAD(P)+) OBSOLETE. The chemical reactions and pathways resulting in the formation of glutamate, catalyzed by the enzyme glutamate dehydrogenase (NADP+). CHEBI:139127 C-terminal S-cyano-L-cysteinate residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139127 GO:0019265 glycine biosynthetic process, by transamination of glyoxylate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019265 glycine formation, by transamination of glyoxylate|glycine synthesis, by transamination of glyoxylate|glycine anabolism, by transamination of glyoxylate The chemical reactions and pathways resulting in the formation of glycine by the transamination of glyoxylate. CHEBI:139120 carotenoid beta-end group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139120 GO:0019266 asparagine biosynthetic process from oxaloacetate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019266 MetaCyc:ASPARAGINE-BIOSYNTHESIS asparagine anabolism from oxaloacetate|asparagine synthesis from oxaloacetate|asparagine formation from oxaloacetate The chemical reactions and pathways resulting in the formation of asparagine from other compounds, including oxaloacetate. CHEBI:139121 (3E,5Z)-dodecadienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139121 GO:0019263 adamantanone catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019263 MetaCyc:P481-PWY adamantanone catabolism|adamantanone degradation|adamantanone breakdown The chemical reactions and pathways resulting in the breakdown of adamantanone, tricyclo(3.3.1.13,7)decanone, a white crystalline solid used as an intermediate for microelectronics in the production of photoresists. CHEBI:139122 (3R)-3-hydroxy-2,3-dihydrotabersonine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139122 CHEBI:72650 cyanidin 3-O-[6-O-(4-O-beta-D-glucosyl-p-coumaroyl)-2-O-(beta-D-xylosyl)-beta-D-glucosyl]-5-O-(6-O-malonyl-beta-D-glucoside)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72650 GO:0019264 glycine biosynthetic process from serine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019264 MetaCyc:GLYSYN-PWY glycine anabolism from serine|glycine synthesis from serine|glycine formation from serine The chemical reactions and pathways resulting in the formation of glycine from other compounds, including serine. CHEBI:72651 9-HODE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72651 CHEBI:72663 9,10-DiHOME biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72663 GO:0019240 citrulline biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019240 MetaCyc:CITRULBIO-PWY citrulline formation|citrulline biosynthesis|citrulline anabolism|citrulline synthesis The chemical reactions and pathways resulting in the formation of citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins. CHEBI:72665 12,13-DiHOME biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72665 GO:0034877 isonicotinate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034877 UM-BBD_reactionID:r1337 Catalysis of the reaction: isonicotinate + acceptor + H2O = 2-hydroxyisonicotinate + reduced acceptor. GO:0034878 2-hydroxyisonicotinate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034878 UM-BBD_reactionID:r1338 Catalysis of the reaction: 2-hydroxyisonicotinate + acceptor + H2O = citrazinate + reduced acceptor. GO:0034879 2,3,6-trihydroxyisonicotinate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034879 UM-BBD_reactionID:r1340 Catalysis of the reaction: 2,3,6-trihydroxyisonicotinate = 2,3,6-trihydroxypyridine + CO2. GO:0034870 pinacolone 5-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034870 UM-BBD_reactionID:r12979 Catalysis of the reaction: 2,2-dimethyl-3-pentanone + 1/2 O2 = 1-hydroxy-4,4-dimethylpentan-3-one. GO:0034871 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034871 UM-BBD_reactionID:r1308 Catalysis of the reaction: 1-hydroxy-4,4-dimethylpentan-3-one = 4,4-dimethyl-3-oxopentanal + 2 H+ + 2 e-. GO:0034872 trans-geranyl-CoA isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034872 EC:5.2.1.-|UM-BBD_reactionID:r1310 Catalysis of the reaction: trans-geranyl-CoA = cis-geranyl-CoA. GO:0034873 thioacetamide S-oxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034873 UM-BBD_reactionID:r1312 Catalysis of the reaction: thioacetamide + O2 + 2 H+ + 2 e- = thioacetamide S-oxide + H2O. GO:0034874 thioacetamide S-oxide S-oxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034874 UM-BBD_reactionID:r1313 Catalysis of the reaction: thioacetamide S-oxide + O2 + 2 H+ + 2 e- = thioacetamide S,S-dioxide + H2O. GO:0034875 caffeine oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034875 EC:1.17.5.-|UM-BBD_reactionID:r1321 Catalysis of the reaction: caffeine + O2 + 2 H+ + 2 e- = 1,3,7-trimethyluric acid + H2O. GO:0019238 cyclohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019238 Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2, in a reaction that involves the opening of a ring. GO:0034876 isonicotinic acid hydrazide hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034876 UM-BBD_reactionID:r1336 Catalysis of the reaction: isoniazid + H2O = isonicotinate + hydrazine. GO:0019239 deaminase activity biolink:MolecularActivity go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0019239 Reactome:R-HSA-9014641 Catalysis of the removal of an amino group from a substrate, producing ammonia (NH3). GO:0019236 response to pheromone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019236 pheromone response Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus. GO:0019237 centromeric DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019237 centromere binding Interacting selectively and non-covalently with a centromere, a region of chromosome where the spindle fibers attach during mitosis and meiosis. GO:0019234 sensory perception of fast pain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019234 The series of events required for an organism to receive a fast pain stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. Fast pain is often subjectively described as a sharp or stabbing pain; in humans, the signals from a fast pain stimulus are perceived and relayed along myelinated A-delta fibers to the central nervous system, reaching their target in about 0.1 seconds. GO:0019235 sensory perception of slow pain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019235 The series of events required for an organism to receive a slow pain stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. Slow pain is often subjectively described as an aching or throbbing pain; in humans, the signals from a slow pain stimulus are perceived and relayed along unmyelinated C fibers to the central nervous system, reaching their target in about 1 second. Slow pain is often associated with tissue destruction. CHEBI:33094 (S)-3-aminoisobutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_33094 GO:0019232 perception of rate of movement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019232 kinesthesia The series of events by which an organism senses the speed and direction of movement of the body and its parts. GO:0019233 sensory perception of pain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019233 Wikipedia:Nociception nociception|perception of physiological pain The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process. GO:0019230 proprioception biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019230 Wikipedia:Proprioception The series of events by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception is mediated by proprioceptors, sensory nerve terminals found in muscles, tendons, and joint capsules, which give information concerning movements and position of the body. The receptors in the labyrinth are sometimes also considered proprioceptors. GO:0019231 perception of static position biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019231 The perception of the orientation of different parts of the body with respect to one another. CHEBI:72662 DiHOME biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72662 CHEBI:72674 versicolorin B biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72674 GO:0019250 aerobic cobalamin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019250 MetaCyc:P381-PWY cobalamin biosynthesis, aerobic|cobalamin biosynthetic process, aerobic|aerobic cobalamin anabolism|aerobic cobalamin synthesis|aerobic cobalamin biosynthesis|aerobic cobalamin formation|aerobic vitamin B12 biosynthetic process|aerobic vitamin B12 biosynthesis|vitamin B12 biosynthetic process, aerobic|vitamin B12 biosynthesis, aerobic The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12) in the presence of oxygen. GO:0019251 anaerobic cobalamin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019251 MetaCyc:COBALSYN-PWY anaerobic cobalamin biosynthesis|anaerobic vitamin B12 biosynthetic process|anaerobic vitamin B12 biosynthesis|vitamin B12 biosynthetic process, anaerobic|vitamin B12 biosynthesis, anaerobic|cobalamin biosynthesis, anaerobic|cobalamin biosynthetic process, anaerobic|anaerobic cobalamin anabolism|anaerobic cobalamin synthesis|anaerobic cobalamin formation The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12) in the absence of oxygen. CHEBI:72676 versicolorin A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72676 CHEBI:72677 dihydrosterigmatocystin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72677 CHEBI:72678 8-O-methyldihydrosterigmatocystin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72678 GO:0034866 2,4,4-trimethylpentanoyl-CoA dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034866 UM-BBD_reactionID:r1276 Catalysis of the reaction: 2,4,4-trimethylpentanoyl-CoA = 2,4,4-trimethylpent-2-enoyl-CoA + 2 H+ + 2 e-. GO:0034867 2,4,4-trimethylpent-2-enoyl-CoA hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034867 UM-BBD_reactionID:r1277 Catalysis of the reaction: 2,4,4-trimethylpent-2-enoyl-CoA + H2O = 2,4,4-trimethyl-3-hydroxypentanoyl-CoA. GO:0034868 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034868 UM-BBD_reactionID:r1273 Catalysis of the reaction: 2,4,4-trimethyl-3-hydroxypentanoyl-CoA = 2,4,4-trimethyl-3-oxopentanoyl-CoA + 2 H+ + 2 e-. GO:0034869 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034869 UM-BBD_reactionID:r1307 Catalysis of the reaction: 2,4,4-trimethyl-3-oxopentanoyl-CoA + OH- = 2,4,4-trimethyl-3-oxopentanoate + CoASH. GO:0034860 2-mercaptobenzothiazole desulfurase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034860 UM-BBD_reactionID:r1288|EC:4.4.1.- Catalysis of the reaction: 2-mercaptobenzothiazole + reduced acceptor = benzothiazole + hydrogen sulfide + oxidized acceptor. GO:0034861 benzothiazole-2-sulfonate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034861 EC:3.13.1.-|UM-BBD_reactionID:r1290 Catalysis of the reaction: benzothiazole-2-sulfonate + H2O = 2-hydroxybenzothiazole + HSO3-. GO:0034862 2,6-dihydroxybenzothiazole monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034862 UM-BBD_reactionID:r1294 Catalysis of the reaction: 2,6-dihydroxybenzothiazole + 1/2 O2 = 2,6,7-trihydroxybenzothiazole. GO:0034863 2,4,4-trimethyl-1-pentanol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034863 UM-BBD_reactionID:r1270 Catalysis of the reaction: 2,4,4-trimethyl-1-pentanol = 2,4,4-trimethylpentanal + 2 H+ + 2 e-. CHEBI:139107 (9S,13S)-1a,1b-dinor-12-oxo-10,15-phytodienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139107 CHEBI:139108 hexadecanoyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139108 GO:0019249 lactate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019249 lactate anabolism|lactate biosynthesis|lactate synthesis|lactate formation The chemical reactions and pathways resulting in the formation of lactate, the anion of lactic acid. GO:0034864 2,4,4-trimethylpentanal dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034864 UM-BBD_reactionID:r1275 Catalysis of the reaction: 2,4,4-trimethylpentanal + H2O = 2,4,4-trimethylpentanoate + 3 H+ + 2 e-. GO:0034865 2,4,4-trimethylpentanoate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034865 UM-BBD_reactionID:r1271 Catalysis of the reaction: 2,4,4-trimethylpentanoate + CoASH = 2,4,4-trimethylpentanoyl-CoA + OH-. GO:0019247 lactate racemization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019247 Partial conversion of one lactate enantiomer into another so that the specific optical rotation is decreased, or even reduced to zero, in the resulting mixture. GO:0019248 D-lactate biosynthetic process from methylglyoxal via (R)-lactaldehyde biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019248 MetaCyc:MGLDLCTANA-PWY D-lactate formation from methylglyoxal via (R)-lactaldehyde|D-lactate anabolism from methylglyoxal via (R)-lactaldehyde|D-lactate synthesis from methylglyoxal via (R)-lactaldehyde The chemical reactions and pathways resulting in the formation of D-lactate from methylglyoxal, via the intermediate (R)-lactaldehyde. GO:0019245 D(-)-lactate biosynthetic process from pyruvate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019245 D(-)-lactate anabolism from pyruvate|D(-)-lactate synthesis from pyruvate|D(-)-lactate formation from pyruvate The chemical reactions and pathways resulting in the formation of D(-)-lactate from other compounds, including pyruvate. CHEBI:139104 (R,R)-3-(3-hydroxydecanoyloxy)decanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139104 GO:0019246 L(+)-lactate biosynthetic process from pyruvate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019246 MetaCyc:PWY-5481 S-lactate biosynthetic process from pyruvate|L(+)-lactate anabolism from pyruvate|L(+)-lactate synthesis from pyruvate|L(+)-lactate formation from pyruvate The chemical reactions and pathways resulting in the formation of L(+)-lactate from other compounds, including pyruvate. CHEBI:139105 (9S,13S)-1a,1b-dinor-10,11-dihydro-12-oxo-15-phytoenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139105 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019243 MetaCyc:PWY-5386 D-lactate biosynthetic process from methylglyoxal|D-lactate biosynthesis from methylglyoxal|glyoxalase system|methylglyoxal detoxification|methylglyoxal catabolism to D-lactate via S-lactoyl-glutathione|methylglyoxal breakdown to D-lactate|methylglyoxal degradation to D-lactate The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into D-lactate via the intermediate S-lactoyl-glutathione. Glutathione is used in the first step of the pathway and then regenerated in the second step. CHEBI:72670 (2S)-versicolorone(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72670 GO:0019244 lactate biosynthetic process from pyruvate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019244 Reactome:R-HSA-71849.1 lactate anabolism from pyruvate|lactate synthesis from pyruvate|lactate formation from pyruvate|pyruvate fermentation to lactate The chemical reactions and pathways resulting in the formation of lactate from other compounds, including pyruvate. CHEBI:72671 (2S,3S)-versiconal hemiacetal acetate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72671 GO:0019241 citrulline catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019241 MetaCyc:CITRULLINE-DEG-PWY citrulline catabolism|citrulline degradation|citrulline breakdown The chemical reactions and pathways resulting in the breakdown of citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins. CHEBI:72672 (2S-3S)-versiconal hemiacetal biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72672 GO:0019242 methylglyoxal biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019242 methylglyoxal anabolism|methylglyoxal synthesis|methylglyoxal formation|methylglyoxal biosynthesis The chemical reactions and pathways resulting in the formation of methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid. CHEBI:72673 (3S)-versiconol acetate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72673 CHEBI:140195 21-phosphorifampicin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140195 CHEBI:139197 2-hydroxy fatty acid anion 24:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139197 CHEBI:139198 hydroxy fatty acid anion 24:0 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139198 CHEBI:139199 2-hydroxy fatty acid anion 26:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139199 CHEBI:140182 hydroxyalbendazole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140182 CHEBI:140183 (3R)-2'-hydroxyisoflavanones biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140183 CHEBI:140181 (3R,4R)-4,2'-dihydroxyisoflavans biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140181 CHEBI:140188 2alpha-hydroxy-ent-isokaurene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140188 CHEBI:140189 omega-hydroxy-beta-dihydromenaquinone-9 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140189 CHEBI:140184 hydroxyfenbendazole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140184 CHEBI:139182 4-(beta-D-glucopyranuronosyloxy)retinoate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139182 CHEBI:139183 5,6-epoxyretinoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139183 CHEBI:139184 1-O-(5,6-epoxyretinoyl)-beta-D-glucuronate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139184 CHEBI:140170 N(4)-{beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-[beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-[beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-Asn residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140170 CHEBI:139185 1-O-(4-oxoretinoyl)-beta-D-glucuronate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139185 CHEBI:139181 1-O-(all-trans-retinoyl)-beta-D-glucuronate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139181 CHEBI:140179 3'-L-prolyl-AMP(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140179 CHEBI:139179 4,4'-diapolycopen-4-oic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139179 GO:0019199 transmembrane receptor protein kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019199 Reactome:R-HSA-8983059|Reactome:R-HSA-8983063 Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: a protein + ATP = a phosphoprotein + ADP. GO:0019197 phosphoenolpyruvate-dependent sugar phosphotransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0019197 Includes phosphoenolpyruvate-protein phosphatase (enzyme I of the phosphotransferase system) and protein-N(PI)-phosphohistidine-sugar phosphotransferase (enzyme II of the phosphotransferase system). GO:0019198 transmembrane receptor protein phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0019198 Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. CHEBI:139193 2-hydroxy fatty acid anion 20:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139193 CHEBI:139194 hydroxy fatty acid anion 20:0 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139194 CHEBI:140161 phosphatidylcholine (20:4/16:0) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140161 CHEBI:139195 2-hydroxy fatty acid anion 22:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139195 CHEBI:139196 hydroxy fatty acid anion 22:0 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139196 CHEBI:139190 hydroxy fatty acid anion 16:0 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139190 CHEBI:139191 2-hydroxy fatty acid anion 18:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139191 CHEBI:139192 hydroxy fatty acid anion 18:0 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139192 CHEBI:140168 N(4)-{alpha-Neu5Ac-(2->6)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-[beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-[beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-Asn(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140168 CHEBI:140169 N(4)-{beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-[beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-[beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-Asn(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140169 CHEBI:140165 Brassica napus metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_140165 OBA:1001065 cell morphology biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_1001065 morphology of cell The morphology of a cell. CHEBI:139186 retinoid glucosiduronic acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139186 CHEBI:139187 2-hydroxy fatty acid anion 14:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139187 CHEBI:139188 hydroxy fatty acid anion 14:0 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139188 CHEBI:139189 2-hydroxy fatty acid anion 16:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139189 GO:0044140 obsolete negative regulation of growth of symbiont on or near host surface biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044140 OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the increase in the symbiont's size or mass on or near the cells or tissues of the host organism. GO:0010808 positive regulation of synaptic vesicle priming biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010808 Any process that increases the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion. GO:0009819 drought recovery biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009819 drought tolerance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of prolonged deprivation of water that restores that organism to a normal (non-stressed) condition. GO:0044141 obsolete negative regulation of development of symbiont on or near host surface biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044141 OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the symbiont's progression from an initial condition to a later condition, on or near the cells or tissues of the host organism. GO:0010809 negative regulation of synaptic vesicle priming biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010809 Any process that decreases the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion. GO:0010806 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010806 CHEBI:23673 2,6-diaminopimelic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23673 GO:0010807 regulation of synaptic vesicle priming biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0010807 Any process that modulates the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion. CHEBI:23677 diazole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23677 GO:0044148 obsolete positive regulation of growth of symbiont involved in interaction with host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044148 positive regulation of growth of symbiont during interaction with host OBSOLETE. Any process that activates or increases the frequency, rate or extent of the increase in size or mass of an organism occurring in, on or near the exterior of its host organism. GO:0010800 positive regulation of peptidyl-threonine phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010800 Any process that increases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine. GO:0044149 positive regulation of development of symbiont involved in interaction with host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044149 positive regulation of development of symbiont during interaction with host Any process that activates or increases the frequency, rate or extent of the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism. GO:0010801 negative regulation of peptidyl-threonine phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010801 Any process that decreases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine. GO:0044146 obsolete negative regulation of growth of symbiont involved in interaction with host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044146 negative regulation of growth of symbiont during interaction with host OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the increase in size or mass of an organism occurring in, on or near the exterior of its host organism. GO:0044147 negative regulation of development of symbiont involved in interaction with host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044147 negative regulation of development of symbiont during interaction with host Any process that stops, prevents, or reduces the frequency, rate or extent of the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism. GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010804 negative regulation of TNF-mediated signaling pathway|negative regulation of tumor necrosis factor-mediated signalling pathway|negative regulation of TNF signaling Any process that decreases the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor. GO:0044144 obsolete modulation of growth of symbiont involved in interaction with host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044144 modulation of growth of symbiont during interaction with host OBSOLETE. Any process that modulates the frequency, rate or extent of the increase in size or mass of an organism occurring in, on or near the exterior of its host organism. GO:0044145 modulation of development of symbiont involved in interaction with host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044145 modulation of development of symbiont during interaction with host Any process that modulates the frequency, rate or extent of the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism. GO:0010805 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010805 CHEBI:23671 2,6-diaminopimelate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23671 GO:0044142 obsolete positive regulation of growth of symbiont on or near host surface biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044142 OBSOLETE. Any process that activates or increases the frequency, rate or extent of the symbiont's increase in size or mass on or near the cells or tissues of the host organism. GO:0010802 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010802 GO:0044143 obsolete positive regulation of development of symbiont on or near host surface biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044143 OBSOLETE. Any process that activates or increases the frequency, rate or extent of the symbiont's progression from an initial condition to a later condition, on or near the cells or tissues of the host organism. GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010803 regulation of tumor necrosis factor-mediated signalling pathway|regulation of TNF signaling|regulation of TNF-mediated signaling pathway Any process that modulates the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor. GO:0009810 stilbene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009810 stilbene metabolism The chemical reactions and pathways involving stilbenes, a class of polyketides formed from a molecule of cinnamic acid and three molecules of malonyl-CoA. GO:0009811 stilbene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009811 stilbene synthesis|stilbene formation|stilbene biosynthesis|stilbene anabolism The chemical reactions and pathways resulting in the formation of stilbenes, a class of polyketide compounds formed from cinnamic acid and three molecules of malonyl CoA. UBERON:0004668 fourth ventricle aperture biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004668 aperture of fourth ventricle|aperture of 4th ventricle One of: the 4th ventricle median or lateral apertures. GO:0009812 flavonoid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009812 flavonoid metabolism The chemical reactions and pathways involving flavonoids, a group of water-soluble phenolic derivatives containing a flavan skeleton including flavones, flavonols and flavanoids, and anthocyanins. UBERON:0004666 interventricular septum membranous part biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004666 membranous part of interventricular septum|membranous septum|ventricular membranous septum|membranous interventricular septum|pars membranacea (septi interventricularis)|membranous part interventricular septum|membranous interventricular septum|membranous portion of interventricular septum|ventricle membranous septum|pars membranacea septi interventricularis|cardiac ventricular membranous septum The membranous portion of the wall between the two lower chambers of the heart GO:0009813 flavonoid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009813 Wikipedia:Flavonoid|MetaCyc:PWY1F-FLAVSYN flavonoid anabolism|flavonoid synthesis|flavonoid formation|flavonoid biosynthesis The chemical reactions and pathways resulting in the formation of flavonoids, a group of phenolic derivatives containing a flavan skeleton. UBERON:0004667 interventricular septum muscular part biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004667 cardiac ventricular muscular septum|muscular interventricular septum|muscular septum|pars muscularis septi interventricularis|muscular part interventricular septum|septum membranaceum|pars muscularis (septi interventricularis)|muscular part of interventricular septum|ventricular muscular septum|muscular interventricular septum The muscular portion of the wall between the two lower chambers of the heart GO:0009814 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009814 UBERON:0004664 aorta tunica adventitia biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004664 tunica adventitia of aorta the outermost layer of the aorta wall, containing connective tissue and collagen and elastic fibers GO:0009815 1-aminocyclopropane-1-carboxylate oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009815 RHEA:23640|KEGG_REACTION:R07214|EC:1.14.17.4|MetaCyc:ETHYL-RXN ethylene-forming enzyme|aminocyclopropanecarboxylate oxidase activity|ethene-forming enzyme|ACC oxidase activity|1-aminocyclopropane-1-carboxylate oxygenase (ethylene-forming) Catalysis of the reaction: 1-aminocyclopropane-1-carboxylate + L-ascorbate + O(2) = CO(2) + dehydroascorbate + ethylene + 2 H(2)O + hydrogen cyanide. Ethene is also known as ethylene. UBERON:0004665 muscular coat of seminal vesicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004665 muscular layer of seminal gland|tunica muscularis glandulae vesiculosae|muscle layer of seminal vesicle|muscular coat of seminal gland|tunica muscularis (vesicula seminalis) A muscular coat that is part of a seminal vesicle [Automatically generated definition]. GO:0009816 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009816 GO:0009817 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009817 UBERON:0004663 aorta wall biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004663 aortic wall|wall of aorta An anatomical wall that is part of an aorta, enclosing the luminal space. GO:0009818 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009818 GO:0044151 obsolete growth of host on or near symbiont surface biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044151 growth of organism on or near symbiont surface OBSOLETE. The increase in size or mass of an organism occurring on or near the exterior of its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0010819 regulation of T cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010819 Any process that modulates the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus. GO:0044152 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044152 GO:0010817 regulation of hormone levels biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010817 Any process that modulates the levels of hormone within an organism or a tissue. A hormone is any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. CHEBI:23683 dibenzothiophene 5-oxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_23683 GO:0010818 T cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010818 T-cell chemotaxis The directed movement of a T cell in response to an external stimulus. A T cell is a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex. GO:0044150 obsolete development of host on or near symbiont surface biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044150 development of organism on or near symbiont surface OBSOLETE. The progression of an organism from an initial condition to a later condition, occurring on or near the exterior of its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:23684 dibenzothiophenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23684 UBERON:0004649 sphenoid bone pterygoid process biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004649 processus pterygoideus|pterygoid process of sphenoid bone|processus pterygoideus ossis sphenoidalis|pterygoid process of sphenoid bone|pterygoid processes|processus pterygoideus ossis sphenoidalis|pterygoid plate|pterygoid process|pterygoid process of sphenoid|pterygoid process|pterygoid processus the process projecting downward from either side of the sphenoid bone, in vertebrates divided into two plates, an inner and an outer (sometimes called the lateral and medial); the posterior nares pass through the space, called the pterygoid fossa, between the processes GO:0044159 host thylakoid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044159 A membranous cellular structure within the host cell that bears the photosynthetic pigments in plants, algae, and cyanobacteria. In cyanobacteria thylakoids are of various shapes and are attached to, or continuous with, the host plasma membrane. In eukaryotic host cells they are flattened, membrane-bounded disk-like structures located in the chloroplasts; in the chloroplasts of higher plants the thylakoids form dense stacks called grana. Isolated thylakoid preparations can carry out photosynthetic electron transport and the associated phosphorylation. GO:0010811 positive regulation of cell-substrate adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010811 Any process that increases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules. GO:0010812 negative regulation of cell-substrate adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010812 Any process that decreases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules. GO:0044157 host cell projection biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044157 A prolongation or process extending from a host cell, e.g. a flagellum or axon. GO:0010810 regulation of cell-substrate adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010810 Any process that modulates the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules. GO:0044158 host cell wall biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044158 The rigid or semi-rigid envelope lying outside the host cell membrane of plant, fungal, and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan. GO:0044155 host caveola biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044155 A small pit, depression, or invagination, such as any of the minute pits or incuppings of the host cell membrane formed during pinocytosis, that communicates with the outside of a host cell and extends inward, indenting the host cytoplasm and the host cell membrane. Such caveolae may be pinched off to form free vesicles within the host cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:23681 dibenzothiophene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_23681 GO:0010815 bradykinin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010815 The chemical reactions and pathways resulting in the breakdown of the peptide bradykinin. GO:0010816 calcitonin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010816 The chemical reactions and pathways resulting in the breakdown of the peptide calcitonin. GO:0044156 host cell junction biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044156 A plasma membrane part that forms a specialized region of connection between two host cells or between a host cell and the host extracellular matrix. At a host cell junction, anchoring proteins extend through the host plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix. GO:0010813 neuropeptide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010813 The chemical reactions and pathways resulting in the breakdown of neuropeptides. Neuropeptides are signaling peptides that travel across a synaptic junction. GO:0044153 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044153 GO:0044154 histone H3-K14 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044154 histone H3K14 acetylation|histone H3 acetylation at K14 The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 14 of the histone. GO:0010814 substance P catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010814 The chemical reactions and pathways resulting in the breakdown of the neuropeptide substance P. UBERON:0004650 tongue keratinized epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004650 keratinized epithelium of tongue A keratinized stratified squamous epithelium that is part of a tongue. GO:0009820 alkaloid metabolic process biolink:BiologicalProcess go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0009820 alkaloid metabolism The chemical reactions and pathways involving alkaloids, nitrogen containing natural products which are not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases). GO:0009821 alkaloid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009821 UM-BBD_enzymeID:e0711 alkaloid anabolism|alkaloid synthesis|alkaloid formation|alkaloid biosynthesis The chemical reactions and pathways resulting in the formation of alkaloids, nitrogen-containing natural products which are not otherwise classified as nonprotein amino acids, amines, peptides, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones, or primary metabolite (such as purine or pyrimidine bases). CHEBI:33007 chromium(6+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_33007 GO:0009822 alkaloid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009822 alkaloid breakdown|alkaloid catabolism|alkaloid degradation The chemical reactions and pathways resulting in the breakdown of alkaloids, nitrogen containing natural products not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases). GO:0009823 cytokinin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009823 cytokinin catabolism|cytokinin degradation|cytokinin breakdown The chemical reactions and pathways resulting in the breakdown of cytokinins, a class of adenine-derived compounds that can function in plants as plant growth regulators. GO:0009824 AMP dimethylallyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009824 MetaCyc:RXN-4307|EC:2.5.1.27|KEGG_REACTION:R04038|RHEA:15285 2-isopentenyl-diphosphate:AMP delta2-isopentenyltransferase activity|2-isopentenyl-diphosphate:AMP 2-isopentenyltransferase activity|isopentenyltransferase activity|cytokinin synthase activity|dimethylallyl-diphosphate:AMP dimethylallyltransferase activity|adenylate isopentenyltransferase activity|adenylate dimethylallyltransferase activity Catalysis of the reaction: AMP + dimethylallyl diphosphate = N(6)-(dimethylallyl)adenosine 5'-phosphate + diphosphate. GO:0009825 multidimensional cell growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009825 cell growth in three dimensions|cell growth in two dimensions The process in which a cell irreversibly increases in size in two or three [spatial] dimensions or along two or three axes. GO:0009826 unidimensional cell growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009826 polar cell growth|cell growth along one axis|cell elongation|polarized cell growth|cell growth in one dimension|cell morphogenesis by unidimensional growth The process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis, resulting in the morphogenesis of the cell. GO:0009827 plant-type cell wall modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009827 cellulose and pectin-containing cell wall modification The series of events leading to chemical and structural alterations of an existing cellulose and pectin-containing cell wall that can result in loosening, increased extensibility or disassembly. An example of this is found in Arabidopsis thaliana. GO:0009828 plant-type cell wall loosening biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009828 cellulose and pectin-containing cell wall loosening The series of events causing chemical and structural alterations of an existing cellulose and pectin-containing cell wall that results in greater extensibility of the wall. An example of this is found in Arabidopsis thaliana. UBERON:0004652 humerus diaphysis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004652 shaft of the humerus|corpus humeri|humeral diaphysis|medial humerus|body of the humerus|diaphysis of humerus|shaft of humerus|body of humerus The body or shaft of the humerus is almost cylindrical in the upper half of its extent, prismatic and flattened below, and has three borders and three surfaces. GO:0009829 cell wall modification involved in fruit ripening biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009829 cell wall modification during ripening The series of events resulting in chemical or structural alterations of existing cell walls that contribute to fruit ripening. GO:0044162 host cell cytoplasmic vesicle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044162 The lipid bilayer surrounding a host cell cytoplasmic vesicle. CHEBI:23652 dextrins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23652 GO:0044163 host cytoskeleton biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044163 Any of the various filamentous elements that form the internal framework of host cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the host cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the host cell. The various elements of the host cytoskeleton not only serve in the maintenance of host cellular shape but also have roles in other host cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles. GO:0044160 host thylakoid membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044160 The pigmented membrane of any host thylakoid. GO:0044161 host cell cytoplasmic vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044161 A vesicle formed of membrane or protein, found in the cytoplasm of a host cell. CHEBI:47622 acetate ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47622 UBERON:0004637 otic capsule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004637 otic capsule skeletal element|periotic capsule|otic region|otic capsule|otic capsule element|periotic|auditory capsule|otic capsule endochondral element The capsule surrounding the inner ear mechanism. UBERON:0004638 blood vessel endothelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004638 An endothelium that lines the blood vasculature. Other endothelia may line lymph vessels, the heart GO:0044168 host cell rough endoplasmic reticulum biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044168 host rough endoplasmic reticulum The irregular network of unit membranes, visible only by electron microscopy, that occurs in the host cell cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The host rough ER has ribosomes adhering to the outer surface. GO:0044169 host cell rough endoplasmic reticulum membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044169 host rough endoplasmic reticulum membrane The lipid bilayer surrounding the host cell rough endoplasmic reticulum. GO:0044166 host cell endoplasmic reticulum lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044166 host endoplasmic reticulum lumen The volume enclosed by the membranes of the host cell endoplasmic reticulum. GO:0044167 host cell endoplasmic reticulum membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044167 host endoplasmic reticulum membrane The lipid bilayer surrounding the host cell endoplasmic reticulum. GO:0044164 host cell cytosol biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044164 host cytosol The part of the host cell cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. GO:0044165 host cell endoplasmic reticulum biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044165 host endoplasmic reticulum The irregular network of unit membranes, visible only by electron microscopy, that occurs in the host cell cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The host ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). UBERON:0004647 liver lobule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004647 lobuli hepatis|lobuli hepatici|lobules of liver|lobulus hepaticus|hepatic lobule the polygonal structure of the liver that consists of hepatocytes radiating outward from a hepatic vein UBERON:0004645 urinary bladder urothelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004645 urothelium of urinary bladder|urothelium|transitional epithelium|bladder transitional cell epithelium|transitional epithelium of urinary bladder|urinary bladder transitional epithelium|epithelium of bladder The epithelial lining of the luminal space of the urinary bladder. UBERON:0004641 spleen capsule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004641 tunica fibrosa splenica|capsula splenica|splenic capsule|tunica fibrosa (splen)(lien)|capsule of spleen|Malpighian capsule|fibrous capsule of spleen|fibroelastic coat of spleen the connective tissue that surrounds the spleen GO:0044173 host cell endoplasmic reticulum-Golgi intermediate compartment membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044173 host endoplasmic reticulum-Golgi intermediate compartment membrane|host cell ER-Golgi intermediate compartment membrane|host ER-Golgi intermediate compartment membrane The lipid bilayer surrounding any of the compartments of the host cell ER-Golgi intermediate compartment system. GO:0009808 lignin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009808 lignin metabolism The chemical reactions and pathways involving lignins, a class of polymers of phenylpropanoid units. GO:0009809 lignin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009809 MetaCyc:PWY-361 lignin biosynthesis|lignin anabolism|lignin synthesis|lignin formation The chemical reactions and pathways resulting in the formation of lignins, a class of polymers formed by the dehydrogenetive radical polymerization of various phenylpropanoid monomers. GO:0044174 host cell endosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044174 host endosome A membrane-bounded organelle that carries materials newly ingested by endocytosis. It passes many of the materials to host cell lysosomes for degradation. GO:0044171 host cell smooth endoplasmic reticulum membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044171 host smooth endoplasmic reticulum membrane The lipid bilayer surrounding the host cell smooth endoplasmic reticulum. GO:0044172 host cell endoplasmic reticulum-Golgi intermediate compartment biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044172 host ER-Golgi intermediate compartment|host cell ER-Golgi intermediate compartment A complex system of membrane-bounded compartments located between host cell endoplasmic reticulum (ER) and the host Golgi complex, with a distinctive membrane protein composition; involved in ER-to-Golgi transport. GO:0044170 host cell smooth endoplasmic reticulum biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044170 host smooth endoplasmic reticulum The irregular network of unit membranes, visible only by electron microscopy, that occurs in the host cell cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The host smooth ER has no ribosomes adhering to the outer surface. CHEBI:23666 diamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23666 GO:0044179 hemolysis in other organism biolink:BiologicalProcess go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0044179 hemolysis of red blood cells in other organism|hemolysis of RBCs in other organism|hemolysis of erythrocytes in other organism|hemolysis of cells in other organism The cytolytic destruction of red blood cells, with the release of intracellular hemoglobin, in one organism by another. GO:0044177 host cell Golgi apparatus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044177 host Golgi apparatus A compound membranous cytoplasmic organelle of eukaryotic host cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. GO:0044178 host cell Golgi membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044178 host Golgi membrane The lipid bilayer surrounding any of the compartments of the host cell Golgi apparatus. GO:0044175 host cell endosome membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044175 host endosome membrane The lipid bilayer surrounding a host cell endosome. GO:0044176 host cell filopodium biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044176 host filopodium Thin, stiff protrusion extended by the leading edge of a motile host cell such as a crawling fibroblast or amoeba, or an axonal growth cone; usually approximately 0.1 um wide, 5-10 um long, can be up to 50 um long in axon growth cones; contains a loose bundle of about 20 actin filaments oriented with their plus ends pointing outward. CHEBI:1233 3-(all-trans-octaprenyl)benzene-1,2-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_1233 CHEBI:1235 2-methoxy-6-(all-trans-octaprenyl)phenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_1235 GO:0009800 cinnamic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009800 cinnamic acid synthesis|cinnamic acid formation|cinnamic acid biosynthesis|phenylpropenoic acid biosynthetic process|phenylacrylic acid biosynthesis|phenylacrylic acid biosynthetic process|phenylpropenoic acid biosynthesis|cinnamylic acid biosynthetic process|cinnamylic acid biosynthesis|cinnamic acid anabolism The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid. GO:0009801 cinnamic acid ester metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009801 cinnamic acid ester metabolism The chemical reactions and pathways involving ester derivatives of cinnamic acid, phenylpropenoic acid. GO:0009802 cinnamic acid ester biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009802 phenylacrylic acid ester biosynthesis|phenylacrylic acid ester biosynthetic process|cinnamic acid ester anabolism|cinnamylic acid ester biosynthetic process|cinnamylic acid ester biosynthesis|cinnamic acid ester synthesis|cinnamic acid ester formation|cinnamic acid ester biosynthesis The chemical reactions and pathways resulting in the formation of ester derivatives of cinnamic acid, phenylpropenoic acid. GO:0009803 cinnamic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009803 cinnamylic acid metabolic process|cinnamic acid metabolism|phenylacrylic acid metabolic process|phenylpropenoic acid metabolic process|phenylacrylic acid metabolism|phenylpropenoic acid metabolism|cinnamylic acid metabolism The chemical reactions and pathways involving cinnamic acid, 3-phenyl-2-propenoic acid. GO:0009804 coumarin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009804 coumarin metabolism The chemical reactions and pathways involving coumarins, compounds derived from the phenylacrylic skeleton of cinnamic acids. GO:0009805 coumarin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009805 MetaCyc:PWY-5176 coumarin anabolism|coumarin biosynthesis|coumarin synthesis|coumarin formation The chemical reactions and pathways resulting in the formation of coumarins, a class of compounds derived from the phenylacrylic skeleton of cinnamic acids. CHEBI:1230 sophorose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_1230 GO:0009806 lignan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009806 lignan metabolism The chemical reactions and pathways involving lignans, any member of a class of plant metabolites related to lignins. Lignans are usually found as phenylpropanoid dimers in which the phenylpropanoid units are linked tail to tail and thus having a 2,3 dibenzylbutane skeleton, but higher oligomers can also exist. GO:0009807 lignan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009807 lignan synthesis|lignan formation|lignan biosynthesis|lignan anabolism The chemical reactions and pathways resulting in the formation of lignans, any member of a class of plant metabolites related to lignins. Lignans are usually found as phenylpropanoid dimers in which the phenylpropanoid units are linked tail to tail and thus having a 2,3 dibenzylbutane skeleton, but higher oligomers can also exist. GO:0044184 host cell late endosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044184 A prelysosomal endocytic organelle differentiated from host early endosomes by lower lumenal pH and different protein composition. Host late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center. CHEBI:23630 deoxyinosine phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23630 GO:0044185 host cell late endosome membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044185 The lipid bilayer surrounding a host cell late endosome. GO:0044182 filamentous growth of a population of unicellular organisms biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044182 The process in which a group of unicellular organisms grow in a threadlike, filamentous shape. GO:0044183 protein folding chaperone biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0044183 Reactome:R-HSA-9018785 protein binding involved in protein folding|chaperone activity Binding to a protein or a protein-containing complex to assist the protein folding process. CHEBI:47600 purvalanol A biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_47600 GO:0044180 filamentous growth of a unicellular organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044180 The process in which a unicellular organism grows in a threadlike, filamentous shape. CHEBI:23634 deoxyaldopentose phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23634 CHEBI:23635 deoxypentose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23635 GO:0044181 filamentous growth of a multicellular organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044181 The process in which a multicellular organism grows in a threadlike, filamentous shape. GO:0044188 host cell lysosomal membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044188 The lipid bilayer surrounding the host cell lysosome and separating its contents from the host cell cytoplasm. GO:0044189 obsolete host cell microsome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044189 host cell microsomal membrane|host cell microsome OBSOLETE. Any of the small, heterogeneous, artifactual, vesicular particles, 50-150 nm in diameter, that are formed when some eukaryotic host cells are homogenized and that sediment on centrifugation at 100000 g. GO:0044186 host cell lipid droplet biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044186 host cell lipid adiposome|host cell lipid particle|host cell lipid body Any particle of coalesced lipids in the cytoplasm of a host cell. May include associated proteins. GO:0044187 host cell lysosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044187 A small lytic vacuole that has cell cycle-independent morphology and is found in most host animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and host cell lysosomes have a great variety of morphologies and functions. CHEBI:23638 deoxyribulose phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23638 CHEBI:23639 deoxy sugar biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23639 CHEBI:23636 deoxyribonucleoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23636 GO:0044195 nucleoplasmic reticulum biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044195 nuclear channels Long, dynamic tubular channels, formed by invagination of the nuclear envelope, that extend deep into the nucleoplasm. The channels have an underlying lamina and are implicated in functioning in signaling and transport. CHEBI:23641 deoxyuridine phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23641 GO:0044196 host cell nucleolus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044196 A small, dense body one or more of which are present in the nucleus of eukaryotic host cells. GO:0044193 host cell mitochondrial outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044193 The outer, i.e. cytoplasm-facing, lipid bilayer of the host cell mitochondrial envelope. GO:0044194 cytolytic granule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044194 A specialized secretory lysosome that is present in cells with cytolytic capability such as cytotoxic T lymphocytes and natural killer cells. Cytolytic granules mediate the storage and regulated excretion of lytic molecules for killing of target cells. GO:0044191 host cell mitochondrial membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044191 Either of the lipid bilayers that surround the host cell mitochondrion and form the host cell mitochondrial envelope. GO:0044192 host cell mitochondrial inner membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044192 The inner, i.e. lumen-facing, lipid bilayer of the host cell mitochondrial envelope. It is highly folded to form cristae. CHEBI:23643 depsipeptide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23643 GO:0044190 host cell mitochondrial envelope biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044190 The double lipid bilayer enclosing the host cell mitochondrion and separating its contents from the host cell cytoplasm; includes the intermembrane space. GO:0044199 host cell nuclear envelope biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044199 The double lipid bilayer enclosing the host nucleus and separating its contents from the rest of the host cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space). GO:0044197 Rel homology domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044197 RHD binding Interacting selectively and non-covalently with a Rel Homology Domain (RHD) of a protein. The RHD is found in a family of eukaryotic transcription factors, which includes NF-kappaB, Dorsal, Relish and NFAT. GO:0044198 zf-TRAF domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044198 zinc-finger-TRAF domain binding|zinc finger TRAF-type domain binding|TRAF-type zinc finger domain binding Interacting selectively and non-covalently with a TRAF-type zinc finger domain of a protein. UBERON:0004693 Peyer's patch epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004693 peyer's patch epithelium the specialized epithelium of the Peyer's patch UBERON:0004694 Harderian gland epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004694 epithelium of harderian gland|harderian gland epithelium An epithelium that is part of a Harderian gland [Automatically generated definition]. UBERON:0004692 external naris epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004692 An epithelium that is part of an external naris [Automatically generated definition]. UBERON:0004699 outflow tract endothelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004699 An endothelium that is part of a outflow tract [Automatically generated definition]. UBERON:0004697 Peyer's patch germinal center biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004697 Area of the Peyer's patch where B cells proliferate and differentiate into plasma cells CHEBI:1294 (20R,22R)-20,22-dihydroxycholesterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_1294 UBERON:0004698 vena cava endothelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004698 An endothelium that is part of a vena cava [Automatically generated definition]. UBERON:0004695 arterial system smooth muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004695 A portion of smooth muscle tissue that is part of an arterial system [Automatically generated definition]. UBERON:0004696 venous system smooth muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004696 A portion of smooth muscle tissue that is part of a venous system [Automatically generated definition]. CHEBI:23612 deoxyadenosine phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23612 NCBITaxon:68459 Giardiinae organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_68459 UBERON:0004681 vestibular system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004681 vestibular system|vestibulomotor system|vestibular organ system|equilibrioception system The sensory system for the sense of balance. CHEBI:1269 2-polyprenylphenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_1269 CHEBI:23614 deoxycholate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_23614 UBERON:0004688 costo-cervical trunk biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004688 costocervical trunk|truncus costocervicalis|trunk of costocervical artery The costocervical trunk arises from the upper and back part of the subclavian artery, behind the scalenus anterior on the right side, and medial to that muscle on the left side. Passing backward, it splits into the deep cervical artery and the supreme intercostal artery (or the Highest intercostal artery), which descends behind the pleura in front of the necks of the first and second ribs, and anastomoses with the first aortic intercostal (3rd posterior intercostal artery). As it crosses the neck of the first rib it lies medial to the anterior division of the first thoracic nerve, and lateral to the first thoracic ganglion of the sympathetic trunk. In the first intercostal space, it gives off a branch which is distributed in a manner similar to the distribution of the aortic intercostals. The branch for the second intercostal space usually joins with one from the highest aortic intercostal artery. This branch is not constant, but is more commonly found on the right side; when absent, its place is supplied by an intercostal branch from the aorta. Each intercostal gives off a posterior branch which goes to the posterior vertebral muscles, and sends a small spinal branch through the corresponding intervertebral foramen to the medulla spinalis and its membranes. [WP,unvetted]. UBERON:0004684 raphe nuclei biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004684 nuclei raphes|raphe of mesenchephalon|nuclei raphes|set of raphe nuclei|raphe nuclei set|raphe nuclei|raphe cluster|raphe nucleus The raphe nuclei are thin plates of cells in and immediately adjacent to the sagittal plane. CHEBI:23618 deoxycortisol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23618 CHEBI:23623 deoxyglucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23623 CHEBI:23621 deoxycytidine phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23621 CHEBI:23622 deoxygalactose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23622 CHEBI:23627 deoxyaldohexose phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23627 UBERON:0004679 dentate gyrus molecular layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004679 molecular layer of the dentate gyrus|dentate gyrus molecular layer|molecular layer of dentate gyrus|stratum moleculare gyri dentati The molecular layer of the dentate gyrus that is bounded by the pial surface superficially and the dentate gyrus granule cell layer deep. It is divided into 2 or more sublayers. CHEBI:23628 deoxyhexose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23628 CHEBI:23625 deoxyguanosine phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23625 UBERON:0004675 hypoglossal nerve root biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004675 hypoglossal nerve fibers|hypoglossal nerve root|fibrae nervi hypoglossi|central part of hypoglossal nerve|hypoglossal nerve fiber bundle|root of hypoglossal nerve|hypoglossal nerve tract|central part of hypoglossal nerve|root of hypoglossal nerve|hypoglossal nerve/ root|hypoglossal nerve fibers A nerve root that extends_fibers_into a hypoglossal nerve. UBERON:0004673 trigeminal nerve root biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004673 radix descendens nervi trigemini|root of trigeminal nerve|trigeminal nerve root|descending trigeminal root|root of trigeminal V nerve|trigeminal neural root A nerve root that extends_fibers_into a trigeminal nerve. UBERON:0004674 facial nerve root biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004674 facial nerve/root|facial nerve fibers|fibrae nervi facialis|facial neural root|facial nerve root|facial nerve or its root|root of facial nerve|central part of facial nerve A nerve root that extends_fibers_into a facial nerve. CHEBI:72564 temozolomide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72564 CHEBI:72565 imidazotetrazine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72565 GO:0034976 response to endoplasmic reticulum stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034976 cellular response to endoplasmic reticulum stress|response to ER stress|ER stress response Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen. GO:0044302 dentate gyrus mossy fiber biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044302 NIF_Subcellular:nlx_subcell_20090601 dentate gyrus mossy fibre|granule cell axon Distinctive, unmyelinated axons produced by granule cells. GO:0044303 axon collateral biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044303 NIF_Subcellular:sao1470140754 Any of the smaller branches of an axon that emanate from the main axon cylinder. GO:0034977 ABIN2-NFKB1-MAP3K8 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034977 ABIN2-NFKB1-TPL-1 complex A protein complex that contains the precursor form of NF-kappaB (p105), the NF-kappaB inhibitor ABIN-2, and the kinase TPL-2 (MAP3K8); the complex stabilizes TPL-2 and is involved in signaling in lipopolysaccharide (LPS)-stimulated macrophages. GO:0044300 cerebellar mossy fiber biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044300 NIF_Subcellular:nlx_subcell_20090209 cerebellar mossy fibre An axon arising from cerebellar projecting cells in the cochlea, vestibular nuclei, spinal cord, reticular formation, cerebellar nuclei and basilar pontine nuclei. Mossy fibers enter through all three cerebellar peduncles and send collaterals to the deep cerebellar nuclei, then branch in the white matter and terminate in the granule cell layer. Through this branching, a given mossy fiber can innervate several folia. Mossy fibers synapse on granule cells. The synaptic contacts are made at enlargements along the length of the mossy fiber called mossy fiber rosettes. The enlargements of the rosettes give the axons a mossy-looking appearance in Golgi stained preparations. GO:0034978 PDX1-PBX1b-MRG1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034978 acinar cell-specific C complex A protein complex that contains the homeodomain proteins PDX1, PBX1b and MRG1 (MEIS2) and is involved in the transcriptional regulation of pancreatic acinar cell-specific genes. GO:0044301 climbing fiber biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044301 NIF_Subcellular:nlx_subcell_20090203 climbing fibre The axon of inferior olive neuron that projects to the cerebellar cortex, largely via the inferior cerebellar peduncle. They range in diameter from 1-3 um and are myelinated until they enter the granule cell layer. They give off collaterals to the deep cerebellar nuclei. They synapse extensively with the dendrites of Purkinje cells in the molecular layer, where each fiber branches repeatedly to climb along the Purkinje cell dendritic tree. Each Purkinje cell is innervated by only a single climbing fiber. GO:0034979 NAD-dependent protein deacetylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034979 Reactome:R-HSA-5685953|Reactome:R-HSA-3371467|Reactome:R-HSA-9620532|Reactome:R-HSA-9667952|Reactome:R-HSA-5688289|Reactome:R-HSA-5688294|Reactome:R-HSA-5211239 Catalysis of the removal of one or more acetyl groups from a protein, requiring NAD. GO:0034970 histone H3-R2 methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034970 histone H3R2me|histone H3 R2 methylation|histone lysine H3 R2 methylation The modification of histone H3 by addition of a methyl group to arginine at position 2 of the histone. GO:0044308 axonal spine biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044308 NIF_Subcellular:sao18239917 axon spine A spine that originates from the axon, usually from the initial segment. GO:0044309 neuron spine biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044309 NIF_Subcellular:sao1145756102 spine A small membranous protrusion, often ending in a bulbous head and attached to the neuron by a narrow stalk or neck. GO:0034971 histone H3-R17 methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034971 histone H3 R17 methylation|histone H3R17me|histone lysine H3 R17 methylation The modification of histone H3 by addition of a methyl group to arginine at position 17 of the histone. GO:0034972 histone H3-R26 methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034972 histone lysine H3 R26 methylation|histone H3 R26 methylation|histone H3R26me The modification of histone H3 by addition of a methyl group to arginine at position 26 of the histone. GO:0044306 neuron projection terminus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044306 neuron terminal specialization|neuron projection terminal|nerve terminal The specialized, terminal region of a neuron projection such as an axon or a dendrite. GO:0019339 parathion catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019339 MetaCyc:PARATHION-DEGRADATION-PWY parathion catabolism|parathion degradation|parathion breakdown The chemical reactions and pathways resulting in the breakdown of parathion, a highly toxic organophosphate compound. Degradation of parathion by sunlight or liver enzymes can result in the formation of the active compound paraoxon which interferes with the nervous system through cholinesterase inhibition. GO:0044307 dendritic branch biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044307 NIF_Subcellular:sao884265541 dendrite branch|secondary dendrite A dendrite arising from another dendrite. GO:0034973 Sid2-Mob1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034973 Sid2-Mob1 kinase complex|Sid2p-Mob1p complex|Dbf2p-Mob1p complex A protein complex that contains a protein kinase (Sid2 in S. pombe) and its regulatory subunit (Mob1). The Sid2p-Mob1p kinase complex is a component of the septation initiation network in fission yeast (called the mitotic exit network in S. cerevisiae) and is required for cytokinesis. The analogous complex in S. cerevisiae is called Dbf2p-Mob1p complex. GO:0044304 main axon biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044304 NIF_Subcellular:sao1596975044 axon shaft|axonal shaft|axon trunk The main axonal trunk, as opposed to the collaterals; i.e., excluding collaterals, terminal, spines, or dendrites. GO:0019337 tetrachloroethylene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019337 MetaCyc:PCEDEG-PWY tetrachloroethylene catabolism|tetrachloroethylene breakdown|tetrachloroethene catabolic process|tetrachloroethene catabolism|tetrachloroethylene degradation The chemical reactions and pathways resulting in the breakdown of tetrachloroethylene, a derivative of ethene with the hydrogen atoms replaced by chlorines. GO:0034974 Swi5-Swi2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034974 Swi5 complex A protein complex involved that contains proteins known in Schizosaccharomyces as Swi5 monomers and Swi2, and is involved in mating type switching. GO:0019338 pentachlorophenol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019338 MetaCyc:PCPDEG-PWY pentachlorophenol breakdown|pentachlorophenol catabolism|pentachlorophenol degradation The chemical reactions and pathways resulting in the breakdown of pentachlorophenol, a chlorinated insecticide and fungicide used primarily to protect timber from fungal rot and wood boring insects. Pentachlorophenol is significantly toxic to mammals, plants, and many microorganisms. GO:0034975 protein folding in endoplasmic reticulum biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034975 oxidative protein folding|protein folding in ER A protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation). GO:0044305 calyx of Held biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044305 NIF_Subcellular:sao1684283879 The terminal specialization of a calyciferous axon which forms large synapses in the mammalian auditory central nervous system. GO:0019335 3-methylquinoline catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019335 MetaCyc:PWY-721 3-methylquinoline degradation|3-methylquinoline breakdown|3-methylquinoline catabolism The chemical reactions and pathways resulting in the breakdown of 3-methylquinoline, C10H9N, an aromatic compound composed of a benzene ring and a heterocyclic N-containing ring. UBERON:0004701 venous system endothelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004701 An endothelium that is part of a venous system [Automatically generated definition]. UBERON:0004702 respiratory system blood vessel endothelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004702 A blood vessel endothelium that is part of a respiratory system [Automatically generated definition]. GO:0019336 phenol-containing compound catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019336 MetaCyc:PHENOLDEG-PWY phenol-containing compound catabolism|phenol-containing compound degradation|phenol-containing compound breakdown The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring. GO:0019333 denitrification pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019333 MetaCyc:DENITRIFICATION-PWY The reduction of nitrate to dinitrogen by four reactions; each intermediate is transformed to the next lower oxidation state; also part of cellular bioenergetics; the nitrogen compounds can serve as terminal acceptors for electron transport phosphorylation in place of oxygen. UBERON:0004700 arterial system endothelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004700 An endothelium that is part of an arterial system [Automatically generated definition]. GO:0019334 p-cymene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019334 MetaCyc:PWY-741 p-cymene degradation|p-cymene breakdown|p-cymene catabolism The chemical reactions and pathways resulting in the breakdown of p-cymene, 1-methyl-4-isopropylbenzene, one of the alkyl-substituted aromatic hydrocarbons found in volatile oils from over 100 plants. GO:0019331 anaerobic respiration, using ammonium as electron donor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019331 MetaCyc:P303-PWY|Wikipedia:Anammox anammox|anaerobic ammonium oxidation The oxidation of ammonium (NH4) to nitrogen (N2) in the absence of oxygen, using nitrite (NO2) as the electron acceptor. It is suggested that hydroxylamine and ammonium are combined to yield hydrazine, which is subsequently oxidized to N2. GO:0019332 aerobic respiration, using nitrite as electron donor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019332 MetaCyc:P282-PWY nitrite oxidation The oxidation of nitrite (NO2) to nitrate (NO3), using oxygen (O2) as the electron acceptor. Nitrite oxidation is the final step in nitrification, the oxidation of ammonia to nitrate, and nitrite oxidoreductase (NOR) is the key enzyme complex that catalyzes the conversion of nitrite to nitrate in nitrite oxidizing species. GO:0019330 aldoxime metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019330 MetaCyc:P345-PWY aldoxime metabolism The chemical reactions and pathways involving aldoximes, compounds derived by the reaction of an aldose with hydroxylamine, thus containing the aldoxime group -HC=NOH. CHEBI:72575 alarm pheromone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72575 GO:0019350 teichoic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019350 MetaCyc:TEICHOICACID-PWY teichoic acid formation|teichoic acid biosynthesis|teichoic acid anabolism|teichoic acid synthesis The chemical reactions and pathways resulting in the formation of teichoic acid, any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues. CHEBI:72576 aurones biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72576 CHEBI:72579 tetrahydrochromenochromene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72579 GO:0044313 protein K6-linked deubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044313 A protein deubiquitination process in which a K6-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 6 of the ubiquitin monomers, is removed from a protein. GO:0034965 intronic box C/D RNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034965 intronic box C/D snoRNA processing|intronic box C/D sRNA processing Any process involved in the conversion of a primary box C/D type small nucleolar RNA (snoRNA) transcript that resides within, and is processed from, the intron of a pre-mRNA into a mature box C/D snoRNA. GO:0044314 protein K27-linked ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044314 protein K27-linked polyubiquitination A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 27 of the ubiquitin monomers, is added to a protein. GO:0034966 intronic box H/ACA snoRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034966 Any process involved in the conversion of a primary box H/ACA type small nucleolar RNA (snoRNA) transcript that resides within, and is processed from, the intron of a pre-mRNA into a mature box H/ACA snoRNA. GO:0044311 exoneme biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044311 A dense granule-like organelle of the apical complex of merozoites, released into the parasitophorous vacuole, mediating protease-dependent rupture and parasite exit from the infected erythrocyte. GO:0034967 Set3 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034967 SET3C|HDAC3 complex A histone deacetylase complex that is involved in transcriptional regulation. In S. cerevisiae, this complex consists of Set3p, Snt1p, Hos4p, Sif2p, Cpr1p, Hos2p, and Hst1p. GO:0034968 histone lysine methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034968 The modification of a histone by addition of one or more methyl groups to a lysine residue. GO:0044312 crystalloid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044312 A transient, cytoplasmic organelle found in Plasmodium species that resembles a cytoplasmic inclusion body and whose function is poorly understood. Crystalloids form in ookinetes and disappear after ookinete-to-oocyst transformation. GO:0034969 histone arginine methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034969 The modification of a histone by addition of a methyl group to an arginine residue. GO:0044310 osmiophilic body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044310 A membrane-bounded vesicle found predominantly in Plasmodium female gametocytes, that becomes progressively more abundant as the gametocyte reaches full maturity. These vesicles lie beneath the subpellicular membrane of the gametocyte, and the release of their contents into the parasitophorous vacuole has been postulated to aid in the escape of gametocytes from the erythrocyte after ingestion by the mosquito. GO:0044319 wound healing, spreading of cells biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044319 cell migration involved in wound healing epiboly The migration of a cell along or through a wound gap that contributes to the reestablishment of a continuous surface. GO:0034960 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0034960 GO:0044317 rod spherule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044317 rod photoreceptor spherule|rod cell spherule A specialized neuron projection which is the site of synaptic transmission produced by retinal rod cells. Rod spherules are small round enlargements of the axon (3-5 micrometers diameter) or even extensions of the cell body. GO:0034961 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0034961 GO:0044318 L-aspartate:fumarate oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044318 EC:1.4.3.16 Catalysis of the reaction: L-aspartate + fumarate = alpha-iminosuccinate + succinate. GO:0034962 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0034962 GO:0019348 dolichol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019348 dolichol metabolism The chemical reactions and pathways involving dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units. GO:0044315 protein secretion by the type VII secretion system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044315 The process in which proteins are transferred into the extracellular milieu or directly into host cells, via the type VII protein secretion system. GO:0034963 box C/D RNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034963 box C/D snoRNA processing|box C/D sRNA processing Any process involved in the conversion of a primary box C/D type small RNA transcript into a mature box C/D RNA. GO:0044316 cone cell pedicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044316 cone pedicle A specialized axon terminus which is produced by retinal cone cells. Pedicles are large, conical, flat end-feet (8-10 micrometers diameter) of the retinal cone axon that lie more or less side by side on the same plane at the outer edge of the outer plexiform layer (OPL). GO:0034964 box H/ACA RNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034964 box H/ACA snoRNA processing|box H/ACA sRNA processing Any process involved in the conversion of a primary box H/ACA type small RNA transcript into a mature box H/ACA RNA. GO:0019349 ribitol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019349 ribitol metabolism The chemical reactions and pathways involving ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose. It occurs free in some plants and is a component of riboflavin. GO:0019346 transsulfuration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019346 MetaCyc:PWY-801|Wikipedia:Transsulfuration_pathway transsulphuration|homocysteine-cysteine interconversion The interconversion of homocysteine and cysteine via cystathionine. In contrast with enteric bacteria and mammals, Saccharomyces cerevisiae has two transsulfuration pathways employing two separate sets of enzymes. GO:0019347 GDP-alpha-D-mannosylchitobiosyldiphosphodolichol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019347 MetaCyc:MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS GDP-alpha-D-mannosylchitobiosyldiphosphodolichol anabolism|GDP-alpha-D-mannosylchitobiosyldiphosphodolichol synthesis|GDP-alpha-D-mannosylchitobiosyldiphosphodolichol formation|GDP-alpha-D-mannosylchitobiosyldiphosphodolichol biosynthesis The chemical reactions and pathways resulting in the formation of GDP-alpha-D-mannosylchitobiosyldiphosphodolichol, a substance composed of mannosylchitobiosyldiphosphodolichol in glycosidic linkage with guanosine diphosphate. GO:0019344 cysteine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019344 cysteine anabolism|cysteine synthesis|cysteine formation|cysteine biosynthesis The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid. GO:0019345 cysteine biosynthetic process via S-sulfo-L-cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019345 cysteine formation via S-sulfo-L-cysteine|cysteine synthesis via S-sulfo-L-cysteine|cysteine anabolism via S-sulfo-L-cysteine|cysteine biosynthetic process via S-sulpho-L-cysteine|cysteine biosynthesis via S-sulpho-L-cysteine The chemical reactions and pathways resulting in the formation of cysteine, via the intermediate S-sulfo-L-cysteine. GO:0019342 trypanothione biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019342 MetaCyc:TRYPANOSYN-PWY trypanothione anabolism|trypanothione synthesis|trypanothione formation|trypanothione biosynthesis The chemical reactions and pathways resulting in the formation of trypanothione (N1,N6,-bis(glutathionyl)spermidine) in two steps from glutathione and spermidine via an N1- or N8-glutathionylspermidine intermediate. Trypanothione appears to be an essential redox intermediate in intracellular thiol redox regulation. It also plays a role in protecting against oxidative stress. CHEBI:72571 pro-angiogenic agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72571 CHEBI:72572 isoflavans biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72572 GO:0019343 cysteine biosynthetic process via cystathionine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019343 cysteine anabolism via cystathionine|cysteine synthesis via cystathionine|cysteine formation via cystathionine The chemical reactions and pathways resulting in the formation of cysteine, via the intermediate cystathionine. GO:0019340 dibenzofuran catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019340 MetaCyc:P662-PWY dibenzofuran breakdown|dibenzofuran degradation|dibenzofuran catabolism The chemical reactions and pathways resulting in the breakdown of dibenzofuran, a substance composed of two benzene rings linked by one ether bond and one carbon-carbon bond. CHEBI:72573 triazene derivative biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72573 GO:0019341 dibenzo-p-dioxin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019341 MetaCyc:P661-PWY dibenzo-p-dioxin catabolism|dibenzo-p-dioxin degradation|dibenzo-p-dioxin breakdown The chemical reactions and pathways resulting in the breakdown of dibenzo-p-dioxin, a substance composed of two benzene rings linked by two ether bonds. CHEBI:139200 hydroxy fatty acid anion 26:0 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139200 CHEBI:72587 (R)-noradrenaline(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72587 CHEBI:72588 semisynthetic derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72588 GO:0034954 diphenyl ether 2,3-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034954 EC:1.14.12.-|UM-BBD_reactionID:r1450 Catalysis of the reaction: diphenyl ether + O2 = 2,3-dihydroxydiphenyl ether. GO:0010987 negative regulation of high-density lipoprotein particle clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010987 Any process that decreases the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. GO:0044324 regulation of transcription involved in anterior/posterior axis specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044324 Any process that modulates the frequency, rate or extent of transcription that contributes to the specification of the anterior/posterior axis. GO:0034955 2,3-dihydroxydiphenyl ether dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034955 EC:1.13.11.-|UM-BBD_reactionID:r1451 Catalysis of the reaction: 2,3-dihydroxydiphenyl ether + O2 + H2O = 2-hydroxymuconate + phenol. GO:0010988 regulation of low-density lipoprotein particle clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010988 Any process that modulates the rate, frequency or extent of low-density lipoprotein particle clearance. Low-density lipoprotein particle clearance is the process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. GO:0044325 ion channel binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0044325 Interacting selectively and non-covalently with one or more specific sites on an ion channel, a protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient. GO:0044322 endoplasmic reticulum quality control compartment biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044322 ERQC|ER quality control compartment|ER-derived quality control compartment A subcompartment of the endoplasmic reticulum in which proteins with improper or incorrect folding accumulate. Enzymes in this compartment direct proteins with major folding problems to translocation to the cytosol and degradation, and proteins with minor folding problems to the ER, to interact with chaperon proteins. GO:0034956 diphenyl ether 1,2-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034956 EC:1.13.11.-|UM-BBD_reactionID:r1453 Catalysis of the reaction: diphenyl ether + NADH + O2 + H+ = phenol + catechol + NAD+. GO:0010985 negative regulation of lipoprotein particle clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010985 Any process that decreases the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. GO:0044323 retinoic acid-responsive element binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044323 RARE binding Interacting selectively and non-covalently with a retinoic acid-responsive element, a variable direct repeat of the sequence PuGGTCA spaced by five nucleotides (DR5) found in the promoters of retinoic acid-responsive genes, to which retinoic acid receptors bind. GO:0034957 3-nitrophenol nitroreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034957 UM-BBD_reactionID:r1495 Catalysis of the reaction: 3-nitrophenol + 2 NADH + 2 H+ = 3-hydroxyaminophenol + 2 NAD+ + H2O. GO:0010986 positive regulation of lipoprotein particle clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010986 Any process that increases the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. GO:0044320 cellular response to leptin stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044320 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptin stimulus. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body. It plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism. GO:0034958 aminohydroquinone monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034958 EC:3.5.99.-|UM-BBD_reactionID:r1497 Catalysis of the reaction: aminohydroquinone + 2 e- + 2 H+ + 1/2 O2 = 1,2,4-benzenetriol + NH3. GO:0044321 response to leptin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044321 response to leptin stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptin stimulus. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body. It plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism]. GO:0034959 endothelin maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034959 The process leading to the attainment of the full functional capacity of endothelin by conversion of Big-endothelin substrate into mature endothelin. GO:0010989 negative regulation of low-density lipoprotein particle clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010989 Any process that decreases the rate, frequency or extent of low-density lipoprotein particle clearance. Low-density lipoprotein particle clearance is the process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. GO:0009990 contact guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009990 Cell recognition involving the deposition of specific pathways in the extracellular matrix that guide migrating cells. GO:0010980 positive regulation of vitamin D 24-hydroxylase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010980 Any process that increases the rate, frequency or extent of vitamin D 24-hydroxylase activity. Vitamin D 24-hydroxylase activity catalyzes the hydroxylation of C-24 of any form of vitamin D. GO:0009991 response to extracellular stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009991 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus. GO:0019319 hexose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019319 hexose biosynthesis|hexose anabolism|hexose synthesis|hexose formation The chemical reactions and pathways resulting in the formation of hexose, any monosaccharide with a chain of six carbon atoms in the molecule. GO:0009992 cellular water homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009992 cellular osmoregulation Any process involved in the maintenance of an internal steady state of water within a cell. GO:0009993 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009993 GO:0034950 phenylboronic acid monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034950 UM-BBD_reactionID:r1020 Catalysis of the reaction: phenylboronic acid + O2 + 2 H+ + 2 e- = phenol + B(OH)3. GO:0019317 fucose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019317 MetaCyc:FUCCAT-PWY fucose breakdown|fucose catabolism|fucose degradation The chemical reactions and pathways resulting in the breakdown of fucose (6-deoxygalactose). GO:0010983 positive regulation of high-density lipoprotein particle clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010983 Any process that increases the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. GO:0044328 canonical Wnt signaling pathway involved in positive regulation of endothelial cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044328 canonical Wnt receptor signalling pathway involved in positive regulation of endothelial cell migration|canonical Wnt receptor signaling pathway involved in positive regulation of endothelial cell migration The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the positive regulation of endothelial cell migration. GO:0009994 oocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009994 oocyte cell differentiation The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete. GO:0019318 hexose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019318 hexose metabolism The chemical reactions and pathways involving a hexose, any monosaccharide with a chain of six carbon atoms in the molecule. GO:0010984 regulation of lipoprotein particle clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010984 Any process that modulates the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. GO:0044329 canonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044329 canonical Wnt receptor signalling pathway involved in positive regulation of cell-cell adhesion|canonical Wnt-activated signaling pathway involved in positive regulation of cell-cell adhesion|canonical Wnt receptor signaling pathway involved in positive regulation of cell-cell adhesion The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the positive regulation of cell to cell adhesion. GO:0034951 o-hydroxylaminobenzoate mutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034951 MetaCyc:RXN-8846|UM-BBD_reactionID:r1026|EC:5.4.99.- Catalysis of the reaction: o-hydroxylaminobenzoate = 3-hydroxyanthranilate. GO:0009995 soluble molecule recognition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009995 The recognition of soluble molecules in the environment. GO:0009996 negative regulation of cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009996 downregulation of cell fate specification|down-regulation of cell fate specification|suppression of cell fate|inhibition of cell fate specification|down regulation of cell fate specification Any process that restricts, stops or prevents a cell from adopting a specific cell fate. GO:0010981 regulation of cell wall macromolecule metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010981 Any process that modulates the rate, frequency or extent of cell wall macromolecule metabolism. Cell wall macromolecule metabolic processes are the chemical reactions and pathways involving macromolecules forming, or destined to form, part of the cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. GO:0044326 dendritic spine neck biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044326 NIF_Subcellular:sao1642908940 pedicle|neck|spine neck Part of the dendritic spine that connects the dendritic shaft to the head of the dendritic spine. GO:0019315 D-allose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019315 D-allose biosynthesis|D-allose anabolism|D-allose synthesis|D-allose formation The chemical reactions and pathways resulting in the formation of D-allose, the D-enantiomer of allo-hexose, an aldohexose similar to glucose. GO:0034952 malonate semialdehyde decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034952 UM-BBD_reactionID:r0266 Catalysis of the reaction: malonate semialdehyde + H+ = acetaldehyde + CO2. GO:0034953 perillyl-CoA hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034953 UM-BBD_reactionID:r1002 Catalysis of the reaction: perillyl-CoA + H2O = 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA. GO:0009997 negative regulation of cardioblast cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009997 downregulation of cardioblast cell fate specification|down-regulation of cardioblast cell fate specification|suppression of cardioblast cell fate|inhibition of cardioblast cell fate specification|down regulation of cardioblast cell fate specification Any process that restricts, stops or prevents a cell from specifying into a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. GO:0044327 dendritic spine head biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044327 NIF_Subcellular:sao952643730 spine head Distal part of the dendritic spine, that carries the post-synaptic density. GO:0019316 D-allose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019316 MetaCyc:PWY0-44 D-allose breakdown|D-allose catabolism|D-allose degradation The chemical reactions and pathways resulting in the breakdown of D-allose, the D-enantiomer of allo-hexose, an aldohexose similar to glucose. GO:0010982 regulation of high-density lipoprotein particle clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010982 Any process that modulates the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. GO:0009998 negative regulation of retinal cone cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009998 suppression of retinal cone cell fate|negative regulation of retina cone cell fate specification|suppression of retina cone cell fate|downregulation of retinal cone cell fate specification|down regulation of retinal cone cell fate specification|inhibition of retinal cone cell fate specification|down-regulation of retinal cone cell fate specification Any process that restricts, stops or prevents a cell from specifying into a retinal cone cell. GO:0019313 allose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019313 allose metabolism The chemical reactions and pathways involving allose, allo-hexose, an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3. GO:0009999 negative regulation of auditory receptor cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009999 downregulation of auditory receptor cell fate specification|negative regulation of auditory hair cell fate specification|down-regulation of auditory receptor cell fate specification|suppression of auditory receptor cell fate|inhibition of auditory receptor cell fate specification|suppression of hair cell fate|down regulation of auditory receptor cell fate specification Any process that restricts, stops or prevents a cell from specifying into an auditory hair cell. GO:0019314 D-allose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019314 D-allose metabolism The chemical reactions and pathways involving D-allose, the D-enantiomer of allo-hexose, an aldohexose similar to glucose. CHEBI:1060 2-dehydro-3-deoxy-D-arabinonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_1060 GO:0019311 sorbose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019311 sorbose metabolism The chemical reactions and pathways involving sorbose, the ketohexose xylo-2-hexulose. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid. GO:0019312 L-sorbose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019312 MetaCyc:P302-PWY L-sorbose metabolism The chemical reactions and pathways involving sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose. L-sorbose is formed by bacterial oxidation of sorbitol. CHEBI:72581 rotenones biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72581 CHEBI:72582 Man-1-2-Ins-1-P-Cer(t18:0)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72582 GO:0019310 inositol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019310 MetaCyc:P562-PWY inositol catabolism|myo-inositol catabolic process|vitamin Bh catabolism|myo-inositol catabolism|inositol degradation|inositol breakdown|vitamin Bh catabolic process The chemical reactions and pathways resulting in the breakdown of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms. CHEBI:72584 pentahydroxyflavan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72584 GO:0034943 trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034943 UM-BBD_reactionID:r0989 Catalysis of the reaction: trans-2-methyl-5-isopropylhexa-2,5-dienoic acid + ATP + CoASH = trans-2-methyl-5-isopropylhexa-2,5-dienoyl-CoA + AMP + PPi. GO:0044335 canonical Wnt signaling pathway involved in neural crest cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044335 canonical Wnt receptor signalling pathway involved in neural crest cell differentiation|canonical Wnt receptor signaling pathway involved in neural crest cell differentiation|canonical Wnt-activated signaling pathway involved in neural crest cell differentiation The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in neural crest cell differentiation. GO:0010998 regulation of translational initiation by eIF2 alpha phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010998 eIF2 alpha phosphorylation in response to stress|regulation of translational initiation by eIF2 alpha phosphorylation in response to stress Any process that modulates the frequency, rate or extent of translation initiation in response to stress by the phosphorylation of eIF2 alpha. GO:0010999 regulation of eIF2 alpha phosphorylation by heme biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010999 Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a result of heme levels. GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044336 canonical Wnt receptor signaling pathway involved in negative regulation of apoptosis|canonical Wnt receptor signaling pathway involved in negative regulation of apoptotic process|canonical Wnt receptor signalling pathway involved in negative regulation of apoptosis The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the negative regulation of apoptotic process. GO:0034944 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034944 UM-BBD_reactionID:r0986 Catalysis of the reaction: 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA + NAD+ = 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA + NADH+ + H+. GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044333 Wnt receptor signalling pathway involved in digestive tract morphogenesis|Wnt receptor signaling pathway involved in digestive tract morphogenesis|Wnt-activated signaling pathway involved in digestive tract morphogenesis The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell contributing to the generation and the organization of the digestive tract. GO:0034945 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034945 UM-BBD_reactionID:r0987|EC:2.3.1.- Catalysis of the reaction: 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA + CoASH = 3-isopropylbut-3-enoyl-CoA + propanoyl-CoA. GO:0010996 response to auditory stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010996 response to sound stimulus|response to sound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auditory stimulus. GO:0010997 anaphase-promoting complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010997 APC binding Interacting selectively and non-covalently with an anaphase-promoting complex. A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. GO:0044334 canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044334 canonical Wnt receptor signalling pathway involved in positive regulation of epithelial to mesenchymal transition|canonical Wnt-activated signaling pathway involved in positive regulation of epithelial to mesenchymal transition|canonical Wnt receptor signaling pathway involved in positive regulation of epithelial to mesenchymal transition The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the positive regulation of epithelial cell to mesenchymal cell transition. GO:0034946 3-isopropylbut-3-enoyl-CoA thioesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034946 UM-BBD_reactionID:r0994 Catalysis of the reaction: 3-isopropylbut-3-enoyl-CoA + H2O = 3-isopropylbut-3-enoic acid + CoASH. GO:0044331 cell-cell adhesion mediated by cadherin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044331 The attachment of one cell to another cell via a cadherin, transmembrane proteins having repeating extracellular calcium ion binding domains. CHEBI:47571 N-acetyl-alpha-D-muramic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47571 GO:0034947 terephthalate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034947 UM-BBD_reactionID:r0321 Catalysis of the reaction: terephthalate + H2O = benzoate + HCO3-. GO:0044332 Wnt signaling pathway involved in dorsal/ventral axis specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044332 Wnt receptor signalling pathway involved in dorsal/ventral axis specification|Wnt receptor signaling pathway involved in dorsal/ventral axis specification|Wnt-activated signaling pathway involved in dorsal/ventral axis specification The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell contributing to the establishment, maintenance and elaboration of the dorsal/ventral axis. GO:0034948 2,6-dihydroxypseudooxynicotine hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034948 UM-BBD_reactionID:r0482|EC:3.7.1.- Catalysis of the reaction: 2,6-dihydroxypseudooxynicotine + H2O = 2,6-dihydroxypyridine + 4-methylaminobutyrate. GO:0034949 1,1-dichloroethane reductive dehalogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034949 EC:1.97.1.-|UM-BBD_reactionID:r1008 Catalysis of the reaction: 1,1-dichloroethane + 2 H+ + 2 e- = chloroethane + HCl. GO:0044330 canonical Wnt signaling pathway involved in positive regulation of wound healing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044330 canonical Wnt receptor signaling pathway involved in positive regulation of wound healing|canonical Wnt receptor signalling pathway involved in positive regulation of wound healing|canonical Wnt-activated signaling pathway involved in positive regulation of wound healing The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in positive regulation of wound healing. GO:0010990 regulation of SMAD protein complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010990 Any process that modulates the rate, frequency, or extent of SMAD protein complex assembly. SMAD protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex that contains SMAD proteins. GO:0010991 negative regulation of SMAD protein complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010991 Any process that decreases the rate, frequency, or extent of SMAD protein complex assembly. SMAD protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex that contains SMAD proteins. GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044339 canonical Wnt receptor signalling pathway involved in osteoblast differentiation|canonical Wnt-activated signaling pathway involved in osteoblast differentiation|canonical Wnt receptor signaling pathway involved in osteoblast differentiation The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in osteoblast differentiation. GO:0010994 free ubiquitin chain polymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010994 The process of creating free ubiquitin chains, compounds composed of a large number of ubiquitin monomers. These chains are not conjugated to a protein. GO:0019328 anaerobic gallate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019328 MetaCyc:P3-PWY anaerobic gallic acid catabolism|anaerobic gallic acid catabolic process|gallate fermentation|anaerobic gallate degradation|anaerobic gallate catabolism|anaerobic gallate breakdown The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, in the absence of oxygen. GO:0034940 5-oxo-4,5-dihydropyrrole-2-carboxylate amidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034940 UM-BBD_reactionID:r0984 Catalysis of the reaction: 5-oxo-4,5-dihydropyrrole-2-carboxylate + 2 H2O = 2-oxoglutarate + NH3. GO:0010995 free ubiquitin chain depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010995 The process in which free ubiquitin chains, compounds composed of a large number of ubiquitin monomers, are broken down. GO:0019329 ammonia oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019329 The chemical reactions and pathways by which ammonia or ammonium is converted to molecular nitrogen or another nitrogen compound, with accompanying loss of electrons. GO:0044337 canonical Wnt signaling pathway involved in positive regulation of apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044337 canonical Wnt receptor signaling pathway involved in positive regulation of apoptotic process|canonical Wnt receptor signalling pathway involved in positive regulation of apoptosis|canonical Wnt-activated signaling pathway involved in positive regulation of apoptotic process|canonical Wnt receptor signaling pathway involved in positive regulation of apoptosis The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the positive regulation of apoptotic process. GO:0034941 pyrrole-2-carboxylate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034941 UM-BBD_reactionID:r0970|EC:4.1.1.93 Catalysis of the reaction: pryrole-2-carboxylate + H+ = pyrrole + CO2. GO:0010992 ubiquitin recycling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010992 ubiquitin homeostasis|regulation of ubiquitin homeostasis Any process involved in the maintenance of an internal steady state of ubiquitin monomers and free ubiquitin chains at the level of the cell by recycling ubiquitin from proteasome-bound ubiquitinated intermediates. GO:0019326 nitrotoluene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019326 nitrotoluene metabolism The chemical reactions and pathways involving nitrotoluene, any methylbenzene molecule with NO2 group(s) attached. GO:0019327 lead sulfide oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019327 MetaCyc:P301-PWY lead sulphide oxidation|oxidation of lead sulfide|oxidation of galena The chemical reactions and pathways resulting in the conversion of lead sulfide to lead sulfate. GO:0044338 canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044338 canonical Wnt receptor signalling pathway involved in mesenchymal stem cell differentiation|canonical Wnt-activated signaling pathway involved in mesenchymal stem cell differentiation|canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in mesenchymal stem cell differentiation. GO:0034942 cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034942 UM-BBD_reactionID:r0988 Catalysis of the reaction: cis-2-methyl-5-isopropylhexa-2,5-dienoic acid + ATP + CoASH = cis-2-methyl-5-isopropylhexa-2,5-dienoyl-CoA + AMP + PPi. GO:0010993 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010993 GO:0019324 L-lyxose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019324 MetaCyc:LYXMET-PWY L-lyxose metabolism The chemical reactions and pathways involving L-lyxose, the L-enantiomer of aldopentose lyxo-pentose, the C-2 epimer of xylose. GO:0019325 anaerobic fructose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019325 MetaCyc:ANAEROFRUCAT-PWY anaerobic fructose breakdown|anaerobic fructose catabolism|anaerobic fructose degradation The chemical reactions and pathways resulting in the breakdown of fructose that occurs in the absence of oxygen. GO:0019322 pentose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019322 pentose synthesis|pentose formation|pentose biosynthesis|pentose anabolism The chemical reactions and pathways resulting in the formation of a pentose, any monosaccharide with a chain of five carbon atoms in the molecule. GO:0019323 pentose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019323 pentose degradation|pentose catabolism|pentose breakdown The chemical reactions and pathways resulting in the breakdown of a pentose, any monosaccharide with a chain of five carbon atoms in the molecule. GO:0019320 hexose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019320 hexose degradation|hexose catabolism|hexose breakdown The chemical reactions and pathways resulting in the breakdown of hexose, any monosaccharide with a chain of six carbon atoms in the molecule. CHEBI:72593 15-ketoprostaglandin F1alpha biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72593 GO:0019321 pentose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019321 pentose metabolism The chemical reactions and pathways involving a pentose, any monosaccharide with a chain of five carbon atoms in the molecule. CHEBI:72596 papulacandin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72596 UBERON:0004738 metanephric juxtaglomerular apparatus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004738 juxtaglomerular apparatus of metanephros juxtaglomerular apparatus of the mature vertebrate kidney, or metanephros. UBERON:0004739 pronephric glomerulus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004739 corpuscle|pronephric glomeruli|glomera|pronephric glomus|glomerulus of pronephros|glomus|pronephric glomera The glomus forms from the splanchnic intermediate mesoderm and is the vascularized filtration unit, filtering the blood before it enters the tubules. The glomus is external to the nephron and extends over more than one body segment. UBERON:0004736 metanephric glomerulus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004736 glomerulus of metanephros glomerulus of the mature vertebrate kidney, or metanephros. UBERON:0004737 metanephric collecting duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004737 collecting duct of metanephros|metanephric collecting tubule A collecting duct of renal tubule that is part of a metanephros [Automatically generated definition]. GO:0034932 1-methoxypyrene 6,7-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034932 UM-BBD_reactionID:r0954 Catalysis of the reaction: 1-methoxypyrene + O2 + 2 H+ + 2 e- = 1-methoxypyrene-6,7-oxide + H2O. GO:0010965 regulation of mitotic sister chromatid separation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010965 Any process that modulates the frequency, rate or extent of mitotic sister chromatid separation. Mitotic sister chromatid separation is the process in which sister chromatids are physically detached from each other during mitosis. GO:0044346 fibroblast apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044346 fibroblast apoptosis Any apoptotic process in a fibroblast, a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. GO:0044347 cell wall polysaccharide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044347 cell wall polysaccharide breakdown The chemical reactions and pathways resulting in the breakdown of cell wall polysaccharides. GO:0034933 1-hydroxy-6-methoxypyrene methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034933 UM-BBD_reactionID:r0956 Catalysis of the reaction: 1-hydroxy-6-methoxypyrene + XCH3 = 1,6-dimethoxypyrene + HX. GO:0010966 regulation of phosphate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010966 Any process that modulates the frequency, rate or extent of phosphate transport. Phosphate transport is the directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0034934 phenanthrene-4-carboxylate dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034934 UM-BBD_reactionID:r0939|EC:1.13.11.- Catalysis of the reaction: phenanthrene-4-carboxylate + 2 H+ + 2 e- + O2 = cis-3,4-phenanthrenedihydrodiol-4-carboxylate. GO:0044344 cellular response to fibroblast growth factor stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044344 cellular response to FGF stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an fibroblast growth factor stimulus. GO:0010963 regulation of L-arginine import biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010963 Any process that modulates the frequency, rate or extent of L-arginine import. L-arginine import is the directed movement of L-arginine, the L-enantiomer of 2-amino-5-guanidinopentanoic acid, into a cell or organelle. GO:0034935 tetrachlorobenzene dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034935 UM-BBD_reactionID:r0957|EC:1.13.11.- Catalysis of the reaction: 2,4-dichlorotoluene + NADH + H+ + O2 = 4,6-dichloro-3-methyl-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+. GO:0010964 regulation of heterochromatin assembly by small RNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010964 regulation of chromatin silencing by small RNA|regulation of RNAi-mediated heterochromatin assembly Any process that modulates the frequency, rate or extent of heterochromatin assembly by small RNA. GO:0044345 stromal-epithelial cell signaling involved in prostate gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044345 stromal-epithelial cell signalling involved in prostate gland development The process of transferring information from a stromal cell to an epithelial cell where it is received and interpreted, as part of prostate gland development. GO:0034936 4,6-dichloro-3-methylcatechol 1,2-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034936 UM-BBD_reactionID:r0959|EC:1.13.11.- Catalysis of the reaction: 4,6-dichloro-3-methylcatechol + O2 = 3,5-dichloro-3-methyl-cis,cis-muconate + 2 H+. GO:0044342 type B pancreatic cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044342 pancreatic beta cell proliferation|pancreatic B cell proliferation The multiplication or reproduction of pancreatic B cells, resulting in the expansion of an pancreatic B cell population. Pancreatic B cell are cells of the pancreas that secrete insulin. GO:0010969 regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010969 Any process that modulates the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion. GO:0044343 canonical Wnt signaling pathway involved in regulation of type B pancreatic cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044343 canonical Wnt receptor signalling pathway involved in regulation of type B pancreatic cell proliferation|canonical Wnt-activated signaling pathway involved in regulation of type B pancreatic cell proliferation|canonical Wnt receptor signaling pathway involved in pancreatic beta cell proliferation|canonical Wnt receptor signalling pathway involved in regulation of pancreatic B cell proliferation|canonical Wnt receptor signaling pathway involved in regulation of type B pancreatic cell proliferation|canonical Wnt receptor signaling pathway involved in regulation of pancreatic B cell proliferation The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that modulates the rate or frequency of pancreatic B cell proliferation. Pancreatic B cell are cells of the pancreas that secrete insulin. GO:0034937 perchlorate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034937 EC:1.97.1.-|UM-BBD_reactionID:r0980 Catalysis of the reaction: perchlorate + 2 H+ + 2 e- = chlorate + H2O. GO:0010967 regulation of polyamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010967 Any process that modulates the frequency, rate or extent of polyamine biosynthesis. Polyamine biosynthesis is the chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups. GO:0044340 canonical Wnt signaling pathway involved in regulation of cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044340 canonical Wnt receptor signaling pathway involved in regulation of cell proliferation|canonical Wnt receptor signalling pathway involved in regulation of cell proliferation|canonical Wnt-activated signaling pathway involved in regulation of cell proliferation The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to modulating the rate or frequency of cell proliferation. GO:0034938 pyrrole-2-carboxylate monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034938 UM-BBD_reactionID:r0968|EC:1.14.14.- Catalysis of the reaction: pryrole-2-carboxylate + NADH + O2 + H+ = 5-hydroxypyrrole-2-carboxylate + NAD+ + H2O. CHEBI:23591 dehydroamino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23591 GO:0034939 5-hydroxypyrrole-2-carboxylate tautomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034939 UM-BBD_reactionID:r0969 Catalysis of the reaction: 5-hydroxypyrrole-2-carboxylate = 5-oxo-4,5-dihydropyrrole-2-carboxylate. GO:0010968 regulation of microtubule nucleation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010968 Any process that modulates the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell. GO:0044341 sodium-dependent phosphate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044341 The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore, by a mechanism dependent upon sodium ions. GO:0009970 cellular response to sulfate starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009970 cellular response to sulphate starvation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sulfate. GO:0009971 anastral spindle assembly involved in male meiosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009971 The aggregation, arrangement and bonding together of a set of components to form the anastral spindle in male meiotic cells. GO:0009972 cytidine deamination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009972 The removal of amino group in the presence of water. GO:0010961 cellular magnesium ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010961 Any process involved in the maintenance of an internal steady state of magnesium ions at the level of a cell. GO:0010962 regulation of glucan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010962 Any process that modulates the rate, frequency, or extent of glucan biosynthesis. Glucan biosynthetic processes are the chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues. GO:0009973 adenylyl-sulfate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009973 EC:1.8.99.2|RHEA:24240|MetaCyc:ADENYLYLSULFATE-REDUCTASE-RXN AMP, sulfite:acceptor oxidoreductase (adenosine-5'-phosphosulfate-forming)|APS-reductase|AMP, sulfite:(acceptor) oxidoreductase (adenosine-5'-phosphosulfate-forming)|APS reductase activity|adenylyl-sulphate reductase activity|adenosine phosphosulfate reductase activity|adenosine 5'-phosphosulfate reductase Catalysis of the reaction: AMP + sulfite + acceptor = adenylyl sulfate + reduced acceptor. GO:0034930 1-hydroxypyrene sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034930 UM-BBD_reactionID:r0952 Catalysis of the reaction: 1-hydroxypyrene + XSO3- = 1-pyrenylsulfate + HX. GO:0009974 zeinoxanthin epsilon hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009974 MetaCyc:RXN-5962|EC:1.14.99.-|RHEA:57352 Catalysis of the reaction: zeinoxanthin + NADPH + O2 + H+ = lutein + NADP+ + H2O. Adds a hydroxyl group to the epsilon ring of the alpha-carotene. GO:0044348 plant-type cell wall cellulose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044348 plant-type cell wall polysaccharide breakdown The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, which forms part of the cell wall. GO:0044349 DNA excision biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044349 The removal of a section of DNA from a larger DNA molecule by the making of dual incisions that flank the section to be excised. GO:0034931 1-hydroxypyrene methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034931 UM-BBD_reactionID:r0953 Catalysis of the reaction: 1-hydroxypyrene + XCH3 = 1-methoxypyrene + HX. GO:0009975 cyclase activity biolink:MolecularActivity go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0009975 Catalysis of a ring closure reaction. GO:0010960 magnesium ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010960 Any process involved in the maintenance of an internal steady state of magnesium ions within an organism or cell. UBERON:0004745 parasphenoid biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004745 parabasale|keilbein|os sphenoideum|os parasphenoidale A tooth- or denticle-covered plate which is attached to the sphenoid stem[Palaeos]. GO:0009976 tocopherol cyclase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009976 Catalysis of the reaction: alkene group + alcohol group on same molecule = cyclic ether. Substrates are 2-methyl-6-phytyl-1,4- hydroquinone (forms delta-tocopherol) and 2,3-dimethyl-5-phytyl-1,4-hydroquinone (forms gamma-tocopherol). GO:0009977 proton motive force dependent protein transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009977 delta-pH-dependent protein transporter activity|pH-dependent protein transporter activity|arginine targeting transmembrane transporter activity|twin-arginine targeting transmembrane transporter activity Catalysis of the transfer of proteins from one side of a membrane to the other. Transportation is dependent on pH gradient across the membrane. GO:0009978 allene oxide synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009978 MetaCyc:RXN1F-19|RHEA:25074 linoleate hydroperoxide isomerase|(9Z,11E,14Z)-(13S)-hydroperoxyoctadeca-9,11,14-trienoate 12,13-hydro-lyase [(9Z)-(13S)-12,13-epoxyoctadeca-9,11-dienoate-forming]|HPI|linoleic acid hydroperoxide isomerase Catalysis of the reaction: 13(S)-hydroperoxylinolenate = 12,13(S)-epoxylinolenate + H2O. GO:0009979 16:0 monogalactosyldiacylglycerol desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009979 Catalysis of the introduction of an omega-3 double bond into an unsaturated 16-carbon fatty acid in a monogalactosyldiacylglycerol molecule. UBERON:0004742 dentary biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004742 dentaries|os dentale|dentale|sur-angulaire|dentary bone The dentary is a dermal bone that forms the antero-lateral part of the lower jaw in fishes and amphibians, extending to the whole lower jaw in mammals[VHOG,modified]. GO:0034929 1-hydroxypyrene 7,8-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034929 UM-BBD_reactionID:r0949 Catalysis of the reaction: 1-hydroxypyrene + O2 + 2 H+ + 2 e- = 1-hydroxypyrene-7,8-oxide + H2O. GO:0044350 micropinocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044350 clathrin-independent pinocytosis|single-organism micropinocytosis An endocytosis process that results in the uptake of liquid material by cells from their external environment by invagination of the plasma membrane to form uncoated micropinosomes, differentiated from macropinosomes by their smaller size, on average 95 nm. UBERON:0004729 nematode larval stage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004729 Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew. UBERON:0004727 cochlear nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004727 auditory nerve|vestibulocochlear VIII nerve cochlear component|vestibulocochlear nerve cochlear component|cochlear root of acoustic nerve|cochlear component|cochlear root of eighth cranial nerve|nervus vestibulocochlearis A nerve in the head that carries signals from the cochlea of the inner ear to the brain. It is part of the vestibulocochlear nerve, the 8th cranial nerve which is found in higher vertebrates; the other portion of the 8th cranial nerve is the vestibular nerve which carries spatial orientation information from the semicircular canals. The cochlear nerve is a sensory nerve, one which conducts to the brain information about the environment, in this case acoustic energy impinging on the tympanic membrane. The cochlear nerve arises from within the cochlea and extends to the brainstem, where its fibers make contact with the cochlear nucleus, the next stage of neural processing in the auditory system[WP]. UBERON:0004725 piriform cortex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004725 paleopallium|regio praepiriformis|pyriform lobe|cortex piriformis|eupalaeocortex|olfactory pallium|pyriform cortex|primary olfactory areas|piriform area|piriform lobe|primary olfactory cortex|palaeocortex II|area prepiriformis the subdivision of the laminated olfactory cortex with only three main layers that receive monosynaptic input from the olfactory bulb via the lateral olfactory tract; it is located bilaterally in the ventrolateral forebrain and is commonly divided into anterior and posterior regions GO:0034921 cis-4,5-dihydroxy-4,5-dihydropyrene dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034921 UM-BBD_reactionID:r0935 Catalysis of the reaction: cis-4,5-dihydroxy-4,5-dihydropyrene = 4,5-dihydroxypyrene + 2 H+ + 2 e-. GO:0010976 positive regulation of neuron projection development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010976 positive regulation of neurite biosynthesis|positive regulation of neurite formation|positive regulation of neurite growth|positive regulation of neurite development Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). GO:0044357 regulation of rRNA stability biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044357 regulation of ribosomal RNA stability Any process that modulates the propensity of rRNA molecules to degradation. Includes processes that both stabilize and destabilize rRNAs. GO:0044358 envenomation resulting in hemorrhagic damage to other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044358 A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with vascular damage and hemorrhage in the bitten organism. GO:0034922 4,5-dihydroxypyrene dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034922 UM-BBD_reactionID:r0936|EC:1.13.11.- Catalysis of the reaction: 4,5-dihydroxypyrene + O2 = phenanthrene-4,5-dicarboxylate + 2 H+. GO:0010977 negative regulation of neuron projection development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010977 negative regulation of neurite biosynthesis|negative regulation of neurite development|negative regulation of neurite growth|growth cone collapse|negative regulation of neurite formation Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). GO:0034923 phenanthrene-4,5-dicarboxylate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034923 UM-BBD_reactionID:r0937 Catalysis of the reaction: phenanthrene-4,5-dicarboxylate + H+ = phenanthrene-4-carboxylate + CO2. GO:0010974 negative regulation of division septum assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010974 negative regulation of division septum formation|inhibition of division septum assembly involved in cell cycle cytokinesis Any process that decreases the frequency, rate or extent of division septum formation. division septum formation is he assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. GO:0044355 clearance of foreign intracellular DNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044355 clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine A defense process that protects an organism from invading foreign DNA. GO:0010975 regulation of neuron projection development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010975 regulation of neurite formation|regulation of neurite biosynthesis|regulation of neurite growth|regulation of neurite development Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). GO:0044356 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044356 GO:0034924 cis-3,4-phenanthrenedihydrodiol-4-carboxylate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034924 UM-BBD_reactionID:r0940 Catalysis of the reaction: cis-3,4-phenanthrenedihydrodiol-4-carboxylate = 3,4-dihydroxyphenanthrene + H+ + 2 e- + CO2. GO:0034925 pyrene 4,5-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034925 UM-BBD_reactionID:r0941 Catalysis of the reaction: pyrene + O2 + 2 H+ + 2 e- = pyrene-4,5-oxide + H2O. GO:0044353 micropinosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044353 A membrane-bounded, uncoated intracellular vesicle formed by the process of micropinocytosis. GO:0044354 macropinosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044354 A membrane-bounded, uncoated intracellular vesicle formed by the process of macropinocytosis. GO:0034926 pyrene-4,5-epoxide hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034926 UM-BBD_reactionID:r0942 Catalysis of the reaction: pyrene-4,5-oxide + H2O = trans-4,5-dihydroxy-4,5-dihydropyrene. GO:0044351 macropinocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044351 clathrin-independent pinocytosis|single-organism macropinocytosis An endocytosis process that results in the uptake of liquid material by cells from their external environment by the 'ruffling' of the cell membrane to form heterogeneously sized intracellular vesicles called macropinosomes, which can be up to 5 micrometers in size. GO:0010978 obsolete gene silencing involved in chronological cell aging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010978 OBSOLETE. Any transcriptional or post-transcriptional process, arising in non-dividing cells as they age, carried out at the cellular level that results in long-term gene inactivation. GO:0034927 pyrene 1,2-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034927 UM-BBD_reactionID:r0943 Catalysis of the reaction: pyrene + O2 + 2 H+ + 2 e- = pyrene-1,2-oxide + H2O. GO:0010979 regulation of vitamin D 24-hydroxylase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010979 Any process that modulates the rate, frequency or extent of vitamin D 24-hydroxylase activity. Vitamin D 24-hydroxylase activity catalyzes the hydroxylation of C-24 of any form of vitamin D. GO:0044352 pinosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044352 NIF_Subcellular:sao1925368674 pinocytic vesicle A membrane-bounded, uncoated intracellular vesicle formed by the process of pinocytosis. GO:0034928 1-hydroxypyrene 6,7-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034928 UM-BBD_reactionID:r0946 Catalysis of the reaction: 1-hydroxypyrene + O2 + 2 H+ + 2 e- = 1-hydroxypyrene-6,7-oxide + H2O. GO:0009980 obsolete glutamate carboxypeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009980 N-pteroyl-L-glutamate hydrolase activity|carboxypeptidase G activity|carboxypeptidase G1 activity|carboxypeptidase G2 activity|glutamate carboxypeptidase activity|glutamyl carboxypeptidase activity OBSOLETE. Catalysis of the release of C-terminal glutamate residues from a wide range of N-acylating groups, including peptidyl, aminoacyl, benzoyl, benzyloxycarbonyl, folyl and pteroyl groups. GO:0009981 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009981 GO:0019308 dTDP-mannose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019308 dTDP-mannose anabolism|dTDP-mannose synthesis|dTDP-mannose biosynthesis|dTDP-mannose formation The chemical reactions and pathways resulting in the formation of dTDP-mannose, a substance composed of mannose in glycosidic linkage with deoxyribosylthymine diphosphate. GO:0019309 mannose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019309 MetaCyc:MANNCAT-PWY mannose catabolism|mannose degradation|mannose breakdown The chemical reactions and pathways resulting in the breakdown of mannose, the aldohexose manno-hexose, the C-2 epimer of glucose. GO:0009982 pseudouridine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009982 Reactome:R-HSA-6782381|Reactome:R-HSA-6790905|Reactome:R-HSA-8870289|Reactome:R-HSA-6787566|Reactome:R-HSA-6786583 Catalysis of the reaction: RNA uridine = RNA pseudouridine. Conversion of uridine in an RNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5. GO:0010972 negative regulation of G2/M transition of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010972 negative regulation of mitotic entry Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle. GO:0009983 obsolete tyrosine aminopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009983 tyrosine aminopeptidase activity OBSOLETE. Catalysis of the release of N-terminal tyrosine from a peptide. GO:0019306 GDP-D-rhamnose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019306 MetaCyc:GDPRHAMSYN-PWY GDP-D-rhamnose biosynthesis|GDP-D-rhamnose anabolism|GDP-D-rhamnose synthesis|GDP-D-rhamnose formation The chemical reactions and pathways resulting in the formation of GDP-D-rhamnose, a substance composed of rhamnose in glycosidic linkage with guanosine diphosphate. GO:0019307 mannose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019307 mannose synthesis|mannose biosynthesis|mannose formation|mannose anabolism The chemical reactions and pathways resulting in the formation of mannose, the aldohexose manno-hexose, the C-2 epimer of glucose. GO:0009984 obsolete adenylate forming enzyme activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009984 adenylate forming enzyme activity OBSOLETE. Catalysis of the reaction: substrate + ATP = substrate-AMP + diphosphate. GO:0010973 positive regulation of division septum assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010973 positive regulation of division septum formation involved in cell cycle cytokinesis|positive regulation of division septum formation|upregulation of mitotic division septum assembly Any process that increases the frequency, rate or extent of division septum formation. division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. GO:0009985 obsolete dihydroflavonol(thiole) lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009985 dihydroflavonol(thiole) lyase activity OBSOLETE. (Was not defined before being made obsolete). GO:0044359 modulation of molecular function in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044359 The process in which an organism effects a change in the function of proteins in a second organism. GO:0010970 transport along microtubule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010970 movement along microtubule|microtubule-based transport|establishment of localization by movement along microtubule The movement of organelles or other particles from one location in the cell to another along microtubules, driven by motor activity. GO:0019304 anaerobic rhamnose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019304 anaerobic rhamnose degradation|anaerobic rhamnose breakdown|anaerobic rhamnose catabolism The chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose, that occurs in the absence of oxygen. GO:0009986 cell surface biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0009986 cell associated|cell bound The external part of the cell wall and/or plasma membrane. GO:0019305 dTDP-rhamnose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019305 MetaCyc:DTDPRHAMSYN-PWY|MetaCyc:PWY-3221 dTDP-rhamnose anabolism|dTDP-rhamnose synthesis|dTDP-rhamnose formation|dTDP-rhamnose biosynthesis The chemical reactions and pathways resulting in the formation of dTDP-rhamnose, a substance composed of rhamnose in glycosidic linkage with deoxyribosylthymine diphosphate. GO:0010971 positive regulation of G2/M transition of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010971 positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle|positive regulation of mitotic entry Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle. GO:0034920 pyrene dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034920 UM-BBD_reactionID:r0934|EC:1.13.11.- Catalysis of the reaction: pyrene + 2 H+ + 2 e- + O2 = cis-4,5-dihydroxy-4,5-dihydropyrene. GO:0009987 cellular process biolink:BiologicalProcess go-plus goslim_plant http://purl.obolibrary.org/obo/GO_0009987 cell physiology|cellular physiological process|single-organism cellular process|cell growth and/or maintenance Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. UBERON:0004734 gastrula biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004734 trilaminar germ|blastocystis trilaminaris|trilaminar disc|tri-laminar disk|trilaminar blastoderm|trilaminar blastocyst|tri-laminar disc|gastrula embryo|trilaminar disk Organism at the gastrula stage. GO:0019302 D-ribose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019302 D-ribose anabolism|D-ribose synthesis|D-ribose formation|D-ribose biosynthesis The chemical reactions and pathways resulting in the formation of D-ribose, (ribo-pentose). GO:0009988 cell-cell recognition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009988 Cell recognition between cells. May involve the formation of specialized cell junctions. GO:0019303 D-ribose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019303 MetaCyc:RIBOKIN-PWY D-ribose catabolism|D-ribose degradation|D-ribose breakdown The chemical reactions and pathways resulting in the breakdown of D-ribose (ribo-pentose). UBERON:0004732 segmental subdivision of nervous system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004732 neuromere Any segmental subdivision of a nervous system. Includes metameric developmental segments, such as vertebrates neuromeres. GO:0019300 rhamnose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019300 rhamnose biosynthesis|rhamnose anabolism|rhamnose synthesis|rhamnose formation The chemical reactions and pathways resulting in the formation of rhamnose, the hexose 6-deoxy-L-mannose. GO:0009989 cell-matrix recognition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009989 Cell recognition that involves the interaction of the cell with the extracellular matrix. UBERON:0004733 segmental subdivision of hindbrain biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004733 hindbrain segment|segment of hindbrain An organ subunit that is part of a hindbrain [Automatically generated definition]. GO:0019301 rhamnose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019301 MetaCyc:RHAMCAT-PWY rhamnose degradation|rhamnose catabolism|rhamnose breakdown The chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose. UBERON:0004731 neuromere biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004731 neural segment|neuromeres|neural metamere|neural tube metameric segment|neuromere|neural tube segment A transverse unitary subdivision of the neural tube that shares a common dorsoventral structure (floor, basal, alar, and roof plates), but each having differential molecular identities and fates; they comprise the secondary prosencephalon, diencephalon (prosomeres), the midbrain (mesomeres), and the hindbrain (rhombomeres). GO:0044360 modulation of voltage-gated potassium channel activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044360 Any process in which an organism effects a change in the frequency, rate or extent of the activity of a voltage-gated potassium channel in another organism. GO:0034918 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034918 UM-BBD_reactionID:r0930 Catalysis of the reaction: 3-hydroxy-2-methylhexanoyl-CoA = 2-methyl-3-oxohexanoyl-CoA + 2 H+ + 2 e-. GO:0044361 negative regulation of voltage-gated potassium channel activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044361 Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated potassium channel in another organism. GO:0034919 butyryl-CoA 2-C-propionyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034919 UM-BBD_reactionID:r0931 Catalysis of the reaction: 2-methyl-3-oxohexanoyl-CoA + CoA = propanoyl-CoA + butyryl-CoA. GO:0010949 negative regulation of intestinal phytosterol absorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010949 Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of phytosterols into the blood by absorption from the small intestine. UBERON:0004716 conceptus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004716 embryo plus adnexa The embryo and its adnexa (appendages or adjunct parts) or associated membranes (i.e. the products of conception) The conceptus includes all structures that develop from the zygote, both embryonic and extraembryonic. It includes the embryo as well as the embryonic part of the placenta and its associated membranes - amnion, chorion (gestational sac), and yolk sac[WP]. GO:0034910 6-hydroxy-3-succinoylpyridine hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034910 UM-BBD_reactionID:r1442 Catalysis of the reaction: 6-hydroxy-3-succinoylpyridine + H2O = succinic semialdehyde + 2,5-dihydroxypyridine. GO:0010943 NADPH pyrophosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010943 Catalysis of the reaction: NADPH + H2O = NMNH + ADP. GO:0044368 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044368 GO:0034911 phthalate 3,4-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034911 EC:1.14.12.-|UM-BBD_reactionID:r1444 Catalysis of the reaction: phthalate + O2 + NADH + H+ = phthalate 3,4-cis-dihydrodiol + NAD+. GO:0010944 negative regulation of transcription by competitive promoter binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010944 Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves direct competition for interaction with a promoter binding site. GO:0044369 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044369 GO:0034912 phthalate 3,4-cis-dihydrodiol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034912 MetaCyc:RXN5F9-56|UM-BBD_reactionID:r1445 Catalysis of the reaction: phthalate 3,4-cis-dihydrodiol + NAD+ = 3,4-dihydroxyphthalate + NADH + H+. GO:0010941 regulation of cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010941 Any process that modulates the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death. GO:0044366 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044366 GO:0034913 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0034913 GO:0010942 positive regulation of cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010942 Any process that increases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death. GO:0044367 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044367 GO:0010947 negative regulation of meiotic joint molecule formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010947 Any process that decreases the frequency, rate or extent of meiotic joint molecule formation. Meiotic joint molecule formation is the conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination. GO:0034914 trinitrophenol hydride denitratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034914 UM-BBD_reactionID:r1448|EC:1.7.99.- 2,4,6-trinitrophenol hydride denitratase activity|TNP hydride denitratase activity Catalysis of the reaction: trinitrophenol hydride Meisenheimer complex = 2,4-dinitrophenol + nitrite. Trinitrophenol is also known as TNP. GO:0044364 disruption of cells of other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044364 A process in which an organism has a negative effect on the functioning of the second organism's cells. GO:0044365 envenomation resulting in modulation of platelet aggregation in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044365 envenomation resulting in regulation of platelet aggregation in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change to the frequency, rate or extent of platelet aggregation in the bitten organism. GO:0034915 2-methylhexanoyl-CoA C-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034915 EC:2.3.1.-|UM-BBD_reactionID:r0927 Catalysis of the reaction: 4-methyl-3-oxooctanoyl-CoA + CoA = acetyl-CoA + 2-methylhexanoyl-CoA. GO:0010948 negative regulation of cell cycle process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010948 Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. GO:0044362 negative regulation of molecular function in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044362 Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the function of proteins in a second organism. GO:0010945 CoA pyrophosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010945 Reactome:R-HSA-6809354|Reactome:R-HSA-6810474 conezyme A pyrophosphatase activity Catalysis of the reaction: coenzyme A or its derivatives + H2O = 3',5'-ADP + 4'-phosphopantetheine. GO:0034916 2-methylhexanoyl-CoA dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034916 UM-BBD_reactionID:r0928|EC:1.3.99.- Catalysis of the reaction: 2-methylhexanoyl-CoA = 2-methylhex-2-enoyl-CoA + 2 H+ + e-. GO:0044363 modulation of potassium channel activity in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044363 Any process in which an organism effects a change in the frequency, rate or extent of the activity of a potassium channel in another organism. GO:0010946 regulation of meiotic joint molecule formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010946 Any process that modulates the frequency, rate or extent of meiotic joint molecule formation. Meiotic joint molecule formation is the conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination. GO:0034917 2-methylhex-2-enoyl-CoA hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034917 UM-BBD_reactionID:r0929 Catalysis of the reaction: 2-methylhex-2-enoyl-CoA + H2O = 3-hydroxy-2-methylhexanoyl-CoA. GO:0009950 dorsal/ventral axis specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009950 dorsoventral axis specification|dorsal-ventral axis specification|dorsal/ventral axis determination The establishment, maintenance and elaboration of the dorsal/ventral axis. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism. GO:0009951 polarity specification of dorsal/ventral axis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009951 polarity specification of dorsoventral axis|polarity specification of dorsal-ventral axis Any process resulting in the establishment of polarity along the dorsal/ventral axis. GO:0010940 positive regulation of necrotic cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010940 Any process that increases the rate, frequency or extent of necrotic cell death. Necrotic cell death is a cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents. GO:0009952 anterior/posterior pattern specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009952 anterior/posterior pattern formation The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism. GO:0009953 dorsal/ventral pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009953 dorsal-ventral pattern formation|dorsal/ventral pattern specification|dorsoventral pattern formation The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism. GO:0009954 proximal/distal pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009954 proximal/distal pattern specification The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end). GO:0009955 adaxial/abaxial pattern specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009955 adaxial/abaxial pattern formation The regionalization process in which differences in cell differentiation along the adaxial/abaxial are generated. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure. GO:0009956 radial pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009956 radial pattern specification The regionalization process that results in defined areas around a point in which specific types of cell differentiation will occur. GO:0009957 epidermal cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009957 hypodermal cell fate specification The process in which a cell becomes capable of differentiating autonomously into an epidermal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. GO:0009958 positive gravitropism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009958 root gravitropism The orientation of plant parts towards gravity. GO:0009959 negative gravitropism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009959 shoot gravitropism The orientation of plant parts away from gravity. GO:0044371 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044371 GO:0034907 acetanilide 1,2-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034907 UM-BBD_reactionID:r0723|EC:1.14.12.- Catalysis of the reaction: acetanilide + O2 + 2 H+ + NADH = catechol + NAD+ + acetamide. UBERON:0004709 pelvic appendage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004709 hindlimb/pelvic fin|posterior paired appendage|pelvic appendage|posterior appendage|pelvic limb/fin|posterior limb/fin Paired appendage that consists of the posterior appendicular skeleton and associated soft and hard tissues, but excludes the pelvic girdle and its associated soft and hard tissues. GO:0044372 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044372 GO:0034908 2-chloro-N-isopropylacetanilide 1,2-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034908 UM-BBD_reactionID:r0724|EC:1.14.12.- Catalysis of the reaction: 2-chloro-N-isopropylacetanilide + O2 + 2 H+ + NADH = 2-chloro-N-isopropylacetamide + catechol + NAD+. GO:0034909 6-hydroxypseudooxynicotine dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034909 EC:1.5.99.14|UM-BBD_reactionID:r1441|RHEA:34223 Catalysis of the reaction: 6-hydroxypseudooxynicotine + H2O + OH- = 6-hydroxy-3-succinoylpyridine + 4 H+ + 4 e- + methylamine. UBERON:0004707 pharyngula stage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004707 phylotypic stage|pharyngula A stage that follows the blastula, gastrula and neurula stages. At the pharyngula stage, all vertebrate embryos show remarkable similarities. GO:0044370 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044370 UBERON:0004708 paired limb/fin biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004708 girdle-associated appendage|paired appendage|limb or fin|jointed paired lateral appendage|pelvic/pectoral appendage|pectoral or pelvic appendage|limb/fin An appendage that is part of an appendage girdle complex. UBERON:0004706 bulbus cordis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004706 primitive right ventricle endocardium a transient fetal dilation of the distal (or cranial) heart tube located where the arterial trunk joins the ventral roots of the aortic arches UBERON:0004703 dorsal thalamus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004703 thalamus proper|dorsal thalamus (Anthoney)|dorsal tier of thalamus|thalamus dorsalis|dorsal thalamus|thalamus, pars dorsalis CHEBI:47537 L-glucaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_47537 UBERON:0004704 bone fossa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004704 fossae|depressions|depression|groove|concavity|concavities|fossa A depression or hollow in a bone[WP]. GO:0010954 positive regulation of protein processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010954 positive regulation of protein maturation by peptide bond cleavage Any process that increases the rate, frequency or extent of protein maturation by peptide bond cleavage. GO:0044379 protein localization to actin cortical patch biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044379 protein localisation to actin cortical patch A process in which a protein is transported to, or maintained in, an actin cortical patch. GO:0010955 negative regulation of protein processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010955 negative regulation of protein maturation by peptide bond cleavage Any process that decreases the rate, frequency or extent of protein maturation by peptide bond cleavage. GO:0034900 3-(N-formyl)-formiminopyruvate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034900 EC:3.5.99.-|UM-BBD_reactionID:r1399 Catalysis of the reaction: 3-(N-formyl)-formiminopyruvate + H2O = 3-formiminopyruvate + formate. GO:0044377 RNA polymerase II cis-regulatory region sequence-specific DNA binding, bending biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044377 RNA polymerase II proximal promoter sequence-specific DNA binding, bending|RNA polymerase II proximal promoter region sequence-specific DNA binding, bending|RNA polymerase II promoter proximal region sequence-specific DNA binding, bending|RNA polymerase II core promoter proximal region sequence-specific DNA binding, bending Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II, and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence. GO:0010952 positive regulation of peptidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010952 Any process that increases the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins. GO:0034901 endosulfan hydroxyether dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034901 UM-BBD_reactionID:r1411 Catalysis of the reaction: endosulfan hydroxyether = endosulfan lactone + 2 H+ + 2 e-. GO:0044378 non-sequence-specific DNA binding, bending biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044378 DNA bending involving non-sequence-specific DNA binding The activity of binding selectively and non-covalently to DNA in a sequence-independent manner and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence. GO:0010953 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010953 GO:0034902 endosulfan sulfate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034902 UM-BBD_reactionID:r1387 Catalysis of the reaction: endosulfan sulfate + H2O = endosulfan diol + sulfite. GO:0010958 regulation of amino acid import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010958 regulation of amino acid import Any process that modulates the frequency, rate or extent of amino acid import into a cell. GO:0034903 endosulfan ether monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034903 UM-BBD_reactionID:r1413 Catalysis of the reaction: endosulfan ether + O2 + 2 H+ + 2 e- = endosulfan hydroxyether + H2O. GO:0044375 regulation of peroxisome size biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044375 Any process that modulates the volume of a peroxisome, a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules. CHEBI:23582 defoliant biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23582 GO:0044376 obsolete RNA polymerase II complex import to nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044376 DNA-directed RNA polymerase II core complex localization to nucleus|DNA-directed RNA polymerase II core complex import into nucleus|RNA polymerase II complex import into nucleus|RNA polymerase II complex localisation to nucleus OBSOLETE. The directed movement of the DNA-directed RNA polymerase II core complex from the cytoplasm into the nucleus. GO:0010959 regulation of metal ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010959 Any process that modulates the frequency, rate, or extent of metal ion transport. Metal ion transport is the directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0034904 5-chloro-2-oxopent-4-enoate hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034904 UM-BBD_reactionID:r1436 Catalysis of the reaction: 5-chloro-2-oxopent-4-enoate + H2O = 5-chloro-4-hydroxy-2-oxopentanate. GO:0034905 5-chloro-4-hydroxy-2-oxopentanate aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034905 EC:4.1.3.-|UM-BBD_reactionID:r1437 Catalysis of the reaction: 5-chloro-4-hydroxy-2-oxopentanate = pyruvate + chloroacetaldehyde. GO:0044373 cytokinin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044373 Interacting selectively and non-covalently with a cytokinin, any of a class of adenine-derived compounds that can function in plants as growth regulators. GO:0010956 negative regulation of calcidiol 1-monooxygenase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010956 Any process that decreases the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is the catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O. GO:0034906 N-isopropylaniline 1,2-dixoxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034906 EC:1.14.12.-|UM-BBD_reactionID:r0721 Catalysis of the reaction: N-isopropylaniline + O2 + 2 H+ + NADH = catechol + NAD+ + isopropylamine. GO:0044374 sequence-specific DNA binding, bending biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0044374 DNA bending involving sequence-specific DNA binding The activity of binding selectively and non-covalently to DNA in a sequence-specific manner and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence. GO:0010957 negative regulation of vitamin D biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010957 Any process that decreases the rate, frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3). GO:0009960 endosperm development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009960 The process whose specific outcome is the progression of the endosperm over time, from its formation to the mature structure. The endosperm is formed during fertilization and provides nutrients to the developing embryo. GO:0010950 positive regulation of endopeptidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010950 Any process that increases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins. GO:0009961 response to 1-aminocyclopropane-1-carboxylic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009961 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-aminocyclopropane-1-carboxylic acid stimulus. GO:0009962 regulation of flavonoid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009962 regulation of flavonoid biosynthesis|regulation of flavonoid formation|regulation of flavonoid anabolism|regulation of flavonoid synthesis Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids. GO:0010951 negative regulation of endopeptidase activity biolink:BiologicalProcess go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0010951 Any process that decreases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins. GO:0009963 positive regulation of flavonoid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009963 positive regulation of flavonoid anabolism|upregulation of flavonoid biosynthetic process|positive regulation of flavonoid synthesis|positive regulation of flavonoid formation|stimulation of flavonoid biosynthetic process|up-regulation of flavonoid biosynthetic process|activation of flavonoid biosynthetic process|positive regulation of flavonoid biosynthesis|up regulation of flavonoid biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids. GO:0009964 negative regulation of flavonoid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009964 down regulation of flavonoid biosynthetic process|inhibition of flavonoid biosynthetic process|negative regulation of flavonoid anabolism|negative regulation of flavonoid synthesis|negative regulation of flavonoid formation|down-regulation of flavonoid biosynthetic process|negative regulation of flavonoid biosynthesis|downregulation of flavonoid biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids. GO:0009965 leaf morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009965 The process in which the anatomical structures of the leaf are generated and organized. GO:0009966 regulation of signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009966 regulation of signaling pathway|regulation of signalling pathway Any process that modulates the frequency, rate or extent of signal transduction. GO:0009967 positive regulation of signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009967 up-regulation of signal transduction|upregulation of signal transduction|positive regulation of signaling pathway|up regulation of signal transduction|activation of signal transduction|positive regulation of signalling pathway|stimulation of signal transduction Any process that activates or increases the frequency, rate or extent of signal transduction. UBERON:0004710 pectoral appendage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004710 anterior appendage|forelimb or pectoral fin|anterior paired appendage|forelimb - pectoral fin|forelimb/pectoral fin|pectoral limb/fin|anterior limb/fin Paired appendage that consists of the anterior appendicular skeleton and associated soft and hard tissues, but excludes the pectoral girdle and its associated soft and hard tissues. GO:0009968 negative regulation of signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009968 inhibition of signal transduction|down regulation of signal transduction|negative regulation of signaling pathway|downregulation of signal transduction|negative regulation of signalling pathway|down-regulation of signal transduction Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction. UBERON:0004711 jugular vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004711 vena jugularis|jugular The jugular veins are veins that bring deoxygenated blood from the head back to the heart via the superior vena cava. GO:0009969 xyloglucan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009969 xyloglucan biosynthesis|xyloglucan anabolism|xyloglucan synthesis|xyloglucan formation The chemical reactions and pathways resulting in the formation of xyloglucan, the cross-linking glycan composed of (1->4)-beta-D glucan backbone substituted at regular intervals with beta-D-xylosyl-(1->6) residues, which is present in the primary cell wall of most higher plants. CHEBI:140278 5-hydroxyanthocyanin O-beta-D-glucoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140278 CHEBI:140276 21-phosphorifampicin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_140276 CHEBI:140277 5-hydroxyanthocyanidin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140277 CHEBI:140275 2alpha,3alpha-dihydroxy-ent-isokaurene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140275 CHEBI:139278 calcidiol 3-O-(beta-D-glucuronate) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139278 CHEBI:139274 calcitriol 25-O-(beta-D-glucuronate) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139274 CHEBI:139277 calcidiol 25-O-(beta-D-glucuronate) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139277 CHEBI:139292 chlorophyllide(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139292 CHEBI:140260 (4Z,7Z,10Z,13Z,15E,19Z)-17-hydroxydocosahexaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140260 CHEBI:139291 chlorophyll(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139291 PR:000008630 high mobility group protein B1 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000008630 high mobility group protein 1|HMGB1|HMG1|HMG-1 A protein that is a translation product of the human HMGB1 gene or a 1:1 ortholog thereof. CHEBI:139289 [(2->6)-alpha-D-glucosyl-(1->4)-N,O(9)-diacetyl-alpha-D-neuraminosyl]n polyanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139289 CHEBI:139285 [(2->8)-N,O(7)-diacetyl-alpha-D-neuraminosyl]n polyanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139285 CHEBI:139286 [(2->8)-N,O(9)-diacetyl-alpha-D-neuraminosyl]n polyanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139286 CHEBI:139287 [(2->6)-alpha-D-glucosyl-(1->4)-N-acetyl-alpha-D-neuraminosyl]n polyanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139287 CHEBI:139288 [(2->6)-alpha-D-glucosyl-(1->4)-N,O(7)-diacetyl-alpha-D-neuraminosyl]n polyanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139288 CHEBI:140259 sordaricin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_140259 CHEBI:139258 all-trans-18-hydroxyretinoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139258 GO:0019399 cyclohexanol oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019399 MetaCyc:CYCLOHEXANOL-OXIDATION-PWY The cyclohexanol metabolic process in which cyclohexanol is converted to adipate. GO:0019397 gallate catabolic process via 2-pyrone-4,6-dicarboxylate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019397 MetaCyc:GALLATE-DEGRADATION-I-PWY gallate breakdown via 2-pyrone-4,6-dicarboxylate|gallate degradation via 2-pyrone-4,6-dicarboxylate|gallic acid catabolic process via 2-pyrone-4,6-dicarboxylate|gallic acid catabolism via 2-pyrone-4,6-dicarboxylate The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, via the intermediate 2-pyrone-4,6-dicarboxylate. CHEBI:139252 [8)-alpha-Neu5Ac-(2->]n polyanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139252 GO:0019398 gallate catabolic process via gallate dioxygenase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019398 MetaCyc:GALLATE-DEGRADATION-II-PWY gallate degradation via 4-carboxy-2-hydroxhexa-2,3-dienedioate|gallic acid catabolism via 4-carboxy-2-hydroxhexa-2,3-dienedioate|gallic acid catabolic process via 4-carboxy-2-hydroxhexa-2,3-dienedioate|gallate catabolic process via 4-carboxy-2-hydroxhexa-2,3-dienedioate|gallate breakdown via 4-carboxy-2-hydroxhexa-2,3-dienedioate The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, where the first step is the conversion of gallate to (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate catalyzed by gallate dioxygenase. GO:0019395 fatty acid oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019395 MetaCyc:FAO-PWY The removal of one or more electrons from a fatty acid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen. GO:0019396 gallate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019396 gallate degradation|gallate breakdown|gallate catabolism|gallic acid catabolism|gallic acid catabolic process The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid (3,4,5-trihydroxybenzoic acid). CHEBI:139270 (S)-3-hydroxypentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139270 CHEBI:139271 6beta-hydroxycortisol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139271 CHEBI:139272 3-hydroxypentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139272 CHEBI:139273 4-O-methylxanthohumol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139273 CHEBI:72513 sphingomyelin 34:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72513 CHEBI:72514 sphingomyelin 34:1 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72514 CHEBI:72518 sphingomyelin 36:1 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72518 CHEBI:140241 3-bromo-4-hydroxybenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_140241 CHEBI:140242 3-bromo-4,5-dihydroxybenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_140242 CHEBI:139267 [(3S)-4-(6-methylheptanoyl)-5-oxooxolan-3-yl]methyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139267 CHEBI:139268 (S)-3-hydroxypentanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139268 CHEBI:139269 6beta-hydroxycortisone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139269 GO:0019382 carbon tetrachloride catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019382 carbon tetrachloride degradation|carbon tetrachloride breakdown|carbon tetrachloride catabolism The chemical reactions and pathways resulting in the breakdown of carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations. It is also used as grain fumigant and a chemical intermediate in the production of refrigerants. GO:0019383 (+)-camphor catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019383 MetaCyc:P601-PWY (+)-camphor catabolism|(+)-camphor degradation|(+)-camphor breakdown The chemical reactions and pathways resulting in the breakdown of (+)-camphor, a bicyclic monoterpene ketone. GO:0019380 3-phenylpropionate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019380 MetaCyc:HCAMHPDEG-PWY|MetaCyc:P281-PWY 3-phenylpropionate degradation|3-phenylpropionate breakdown|3-phenylpropionate catabolism The chemical reactions and pathways resulting in the breakdown of 3-phenylpropionate, the anion of phenylpropanoic acid. GO:0019381 atrazine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019381 MetaCyc:P141-PWY atrazine degradation|atrazine breakdown|atrazine catabolism The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide. CHEBI:139240 7(1)-hydroxybacteriochlorophyllide d(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139240 CHEBI:140232 sordaricin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140232 CHEBI:140233 4'-O-demethylsordarin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140233 CHEBI:139239 (R)-3-hydroxypentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139239 GO:0019379 sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019379 MetaCyc:SO4ASSIM-PWY sulphate assimilation, phosphoadenylyl sulphate reduction by a phosphoadenylyl-sulphate reductase (thioredoxin) The pathway by which inorganic sulfate is processed and incorporated into sulfated compounds, where the phosphoadenylyl sulfate reduction step is catalyzed by the enzyme phosphoadenylyl-sulfate reductase (thioredoxin) (EC:1.8.4.8). CHEBI:139235 (3E,5Z)-dodecadienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139235 GO:0019377 glycolipid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019377 glycolipid catabolism|glycolipid degradation|glycolipid breakdown The chemical reactions and pathways resulting in the breakdown of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). CHEBI:139236 (R)-3-hydroxypentanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139236 GO:0019378 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0019378 CHEBI:139237 bacteriochlorophyllide f(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139237 GO:0019375 galactolipid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019375 galactolipid anabolism|galactolipid synthesis|galactolipid formation|galactolipid biosynthesis The chemical reactions and pathways resulting in the formation of galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine. CHEBI:139230 (R,R)-2-oleoylglycero-1-phospho-1'-glycerol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139230 GO:0019376 galactolipid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019376 galactolipid breakdown|galactolipid catabolism|galactolipid degradation The chemical reactions and pathways resulting in the breakdown of galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine. CHEBI:139231 5-methyldeoxycytidine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139231 GO:0019373 epoxygenase P450 pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019373 The chemical reactions and pathways by which arachidonic acid is converted to other compounds including epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids. GO:0019374 galactolipid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019374 galactolipid metabolism The chemical reactions and pathways involving galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine. GO:0019393 glucarate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019393 glucarate biosynthesis|glucarate anabolism|glucarate synthesis|glucarate formation The chemical reactions and pathways resulting in the formation of glucarate, the anion of glucaric acid. GO:0019394 glucarate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019394 MetaCyc:GLUCARDEG-PWY glucarate degradation|glucarate breakdown|glucarate catabolism The chemical reactions and pathways resulting in the breakdown of glucarate, the anion of glucaric acid. GO:0019391 glucuronoside catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019391 MetaCyc:GLUCUROCAT-PWY glucuronoside degradation|glucuronoside breakdown|glucuronoside catabolism|glucuronide catabolic process|glucuronide catabolism The chemical reactions and pathways resulting in the breakdown of glucuronosides, compound composed of a hydroxy compound linked to a glucuronate residue. CHEBI:72533 sphingomyelin 42:1 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72533 GO:0019392 glucarate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019392 glucarate metabolism The chemical reactions and pathways involving glucarate, the dianion of glucaric acid, an aldaric acid derived from either glucose or gulose. There are two enantiomers L- and D-glucarate. CHEBI:72534 sphingomyelin 42:2 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_72534 GO:0019390 glucuronoside biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019390 glucuronoside biosynthesis|glucuronide biosynthetic process|glucuronide biosynthesis|glucuronoside anabolism|glucuronoside synthesis|glucuronoside formation The chemical reactions and pathways resulting in the formation of glucuronosides, compound composed of a hydroxy compound linked to a glucuronate residue. CHEBI:140221 O-[S-(5-chloropyrrole-2-carbonyl)pantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140221 GO:0019388 galactose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019388 MetaCyc:GALDEG-PWY galactose catabolism|galactose degradation|galactose breakdown The chemical reactions and pathways resulting in the breakdown of galactose, the aldohexose galacto-hexose. GO:0019389 glucuronoside metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019389 glucuronoside metabolism|glucuronide metabolism|glucuronide metabolic process The chemical reactions and pathways involving glucuronosides, any compound formed by combination in glycosidic linkage of a hydroxy compound with the anomeric carbon atom of a glucuronate. CHEBI:139248 [4-(6-methylheptanoyl)-5-oxo-2,5-dihydrofuran-3-yl]methyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139248 GO:0019386 methanogenesis, from carbon dioxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019386 MetaCyc:METHANOGENESIS-PWY methane biosynthesis from carbon dioxide|methane biosynthetic process from carbon dioxide The chemical reactions and pathways resulting in the formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other compounds, including carbon dioxide (CO2). GO:0019387 methanogenesis, from methanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019387 MetaCyc:METHFORM-PWY methane biosynthesis from methanol|methane biosynthetic process from methanol The formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other components, including methanol. CHEBI:139242 7(1),7(1)-dihydroxybacteriochlorophyllide d(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139242 GO:0019384 caprolactam catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019384 MetaCyc:P621-PWY caprolactam catabolism|caprolactam degradation|caprolactam breakdown The chemical reactions and pathways resulting in the breakdown of caprolactam, hexahydro-2h-azepin-2-one, a cyclic amide of caproic acid. GO:0019385 methanogenesis, from acetate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019385 MetaCyc:METH-ACETATE-PWY methane biosynthetic process from acetate|methane biosynthesis from acetate The formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other components, including acetate. GO:0019360 nicotinamide nucleotide biosynthetic process from niacinamide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019360 nicotinamide nucleotide formation from niacinamide|nicotinamide nucleotide synthesis from niacinamide|nicotinamide nucleotide anabolism from niacinamide The chemical reactions and pathways resulting in the formation of nicotinamide nucleotide from other compounds, including niacinamide. GO:0019361 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019361 MetaCyc:P2-PWY 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA anabolism|2'-(5''-triphosphoribosyl)-3'-dephospho-CoA synthesis|2'-(5''-triphosphoribosyl)-3'-dephospho-CoA formation|2'-(5''-triphosphoribosyl)-3'-dephospho-CoA biosynthesis The chemical reactions and pathways resulting in the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA, a derivative of coenzyme A. CHEBI:72544 flavonoids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_72544 GO:0034998 oligosaccharyltransferase I complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034998 OSTCI An oligosaccharyltransferase (OST) complex that contains at least seven polypeptides and is the major OST complex in mammalian cells. Of the three forms of mammalian OST complex identified, the OSTI complex has the weakest affinity for ribosomes. GO:0034999 oligosaccharyltransferase II complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034999 OSTCII An oligosaccharyltransferase (OST) complex that contains the seven polypeptides found in OST complex I, plus heterotrimeric Sec61alpha-beta-gamma. Of the three forms of mammalian OST complexes identified, the OSTII complex has intermediate affinity for ribosomes. CHEBI:140211 3-bromo-4,5-dihydroxybenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140211 PR:000008636 3-hydroxy-3-methylglutaryl-coenzyme A reductase biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000008636 HMGCR|HMG-CoA reductase A protein that is a translation product of the human HMGCR gene or a 1:1 ortholog thereof. GO:0034990 nuclear mitotic cohesin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034990 A cohesin complex that mediates sister chromatid cohesion in the nucleus during mitosis; has a subunit composition distinct from that of the meiotic cohesin complex. GO:0034991 nuclear meiotic cohesin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034991 A cohesin complex that mediates sister chromatid cohesion in the nucleus during meiosis; has a subunit composition distinct from that of the mitotic cohesin complex. GO:0034992 microtubule organizing center attachment site biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034992 microtubule organising centre attachment site|MAS|MTOC attachment site A region of the nuclear envelope to which a microtubule organizing center (MTOC) attaches; protein complexes embedded in the nuclear envelope mediate direct or indirect linkages between the microtubule cytoskeleton and the nuclear envelope. GO:0034993 meiotic nuclear membrane microtubule tethering complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034993 SUN-KASH complex|LINC complex|LInker of Nucleoskeleton and Cytoskeleton complex A nuclear membrane protein complex which connects the nuclear outer and inner membranes together, and links links the nuclear lumen to cytoplasmic microtubules during meiosis. CHEBI:140219 O-[S-(4,5-dichloropyrrole-2-carbonyl)pantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140219 GO:0034994 microtubule organizing center attachment site organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034994 MTOC attachment site organization|MAS organization|microtubule organising centre attachment site organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microtubule organizing center attachment site. A microtubule organizing center attachment site is a region of the nuclear envelope to which a microtubule organizing center (MTOC) attaches. GO:0034995 SC5b-7 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034995 A protein complex that consist of complement components C5b6 and C7 stably inserted in a cell membrane. Formation of the SC5b-7 complex is the first phase of membrane attack complex assembly. CHEBI:139217 4-hydroxytryptamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139217 GO:0019359 nicotinamide nucleotide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019359 nicotinamide nucleotide biosynthesis|nicotinamide nucleotide anabolism|nicotinamide nucleotide synthesis|nicotinamide nucleotide formation The chemical reactions and pathways resulting in the formation of nicotinamide nucleotides, any nucleotide that contains combined nicotinamide. CHEBI:139218 secondary nitroalkane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139218 GO:0034996 RasGAP-Fyn-Lyn-Yes complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034996 p21(ras)GAP-Fyn-Lyn-Yes complex, thrombin stimulated A protein complex that consists of a GTPase activator protein (GAP) for Ras and three Src family protein tyrosine kinases, Fyn, Lyn and Yes. The complex is involved in signaling upon platelet activation. CHEBI:140214 3,5-dibromocatechol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140214 GO:0034997 alphav-beta5 integrin-vitronectin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034997 ITGAV-ITGB5-VTN complex A protein complex that comprises one integrin alphav subunit, one integrin beta5 subunit, and vitronectin. GO:0019357 nicotinate nucleotide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019357 nicotinate nucleotide synthesis|nicotinate nucleotide formation|nicotinate nucleotide biosynthesis|nicotinate nucleotide anabolism The chemical reactions and pathways resulting in the formation of nicotinamide nucleotides, any nucleotide that contains combined nicotinate (pyridine 3-carboxylic acid). GO:0019358 nicotinate nucleotide salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019358 MetaCyc:PWY-5381|MetaCyc:PYRIDNUCSAL-PWY nicotinate nucleotide biosynthetic process, salvage pathway|nicotinate nucleotide biosynthesis, salvage pathway The generation of nicotinate nucleotide without de novo synthesis. GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019355 nicotinamide nucleotide formation from aspartate|nicotinamide nucleotide synthesis from aspartate|nicotinamide nucleotide anabolism from aspartate The chemical reactions and pathways resulting in the formation of nicotinamide nucleotide from other compounds, including aspartate. GO:0019356 nicotinate nucleotide biosynthetic process from tryptophan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019356 nicotinate nucleotide anabolism from tryptophan|nicotinate nucleotide synthesis from tryptophan|nicotinate nucleotide formation from tryptophan The chemical reactions and pathways resulting in the formation of nicotinate nucleotide from other compounds, including tryptophan. CHEBI:139215 cochalic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139215 GO:0019353 protoporphyrinogen IX biosynthetic process from glutamate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019353 protoporphyrinogen IX formation from glutamate|protoporphyrinogen IX synthesis from glutamate|protoporphyrinogen IX anabolism from glutamate The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX from other compounds, including glutamate. GO:0019354 siroheme biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019354 MetaCyc:PWY-5194 siroheme biosynthesis|siroheme anabolism|siroheme synthesis|siroheme synthase activity|siroheme formation|sirohaem biosynthesis|sirohaem biosynthetic process The chemical reactions and pathways resulting in the formation of siroheme, a tetrahydroporphyrin with adjacent, reduced pyrrole rings. GO:0019351 dethiobiotin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019351 dethiobiotin anabolism|dethiobiotin synthesis|dethiobiotin biosynthesis|dethiobiotin formation|desthiobiotin biosynthetic process|desthiobiotin biosynthesis The chemical reactions and pathways resulting in the formation of dethiobiotin, a derivative of biotin in which the sulfur atom has been replaced by two hydrogen atoms. GO:0019352 protoporphyrinogen IX biosynthetic process from glycine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019352 protoporphyrinogen IX formation from glycine|protoporphyrinogen IX synthesis from glycine|protoporphyrinogen IX anabolism from glycine The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX from other compounds, including glycine. GO:0019371 cyclooxygenase pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019371 The chemical reactions and pathways by which prostaglandins are formed from arachidonic acid, and in which prostaglandin-endoperoxide synthase (cyclooxygenase) catalyzes the committed step in the conversion of arachidonic acid to the prostaglandin-endoperoxides PGG2 and PGH2. GO:0019372 lipoxygenase pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019372 The chemical reactions and pathways by which an unsaturated fatty acid (such as arachidonic acid or linolenic acid) is converted to other compounds, and in which the first step is hydroperoxide formation catalyzed by lipoxygenase. GO:0019370 leukotriene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019370 Wikipedia:Leukotriene#Leukotriene_synthesis leukotriene biosynthesis|leukotriene anabolism|leukotriene synthesis|leukotriene formation The chemical reactions and pathways resulting in the formation of leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid. GO:0034987 immunoglobulin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034987 Fc receptor binding Interacting selectively and non-covalently with one or more specific sites on an immunoglobulin receptor molecule. GO:0034988 Fc-gamma receptor I complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034988 Interacting selectively and non-covalently with one or more specific sites on the Fc-gamma receptor I complex. The complex functions primarily as an activating receptor for IgG. GO:0034989 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0034989 GO:0034980 FHL2-CREB complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034980 A protein complex that contains CREB and FHL2, and is involved in transcriptional regulation. GO:0034981 FHL3-CREB complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034981 A protein complex that contains CREB and FHL3, and is involved in transcriptional regulation. GO:0034982 mitochondrial protein processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034982 mitochondrial protein modification The peptide cleavage of mitochondrial proteins, including cleavage contributing to their import. GO:0034983 peptidyl-lysine deacetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034983 protein lysine acetylation The removal of an acetyl group from an acetylated lysine residue in a peptide or protein. GO:0034984 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0034984 CHEBI:139228 (R,R)-bis(2-oleoylglycero)-3-phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_139228 GO:0034985 Ecsit-NDUFAF1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034985 Any large protein complex that contains Ecsit and NDUFAF1, is located in the mitochondrion, and is involved in the assembly of complex I of the oxidative phosphorylation system. In mammalian cells, three complexes of approximately 500, 600, and 850 kDa containing the 45 kDa isoform of Ecsit and NDUFAF1 have been observed. CHEBI:140203 3-bromo-4-hydroxybenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140203 GO:0034986 iron chaperone activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034986 Directly binding to and delivering iron ions to a target protein. GO:0019368 fatty acid elongation, unsaturated fatty acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019368 MetaCyc:PWY0-862 Elongation of a fatty acid chain into which one or more C-C double bonds have been introduced. GO:0019369 arachidonic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019369 Wikipedia:Arachidonic_acid arachidonic acid metabolism The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer. GO:0019367 fatty acid elongation, saturated fatty acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019367 MetaCyc:FASYN-ELONG-PWY Elongation of a saturated fatty acid chain. GO:0019364 pyridine nucleotide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019364 pyridine nucleotide catabolism|pyridine nucleotide degradation|pyridine nucleotide breakdown The chemical reactions and pathways resulting in the breakdown of a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base. GO:0019365 pyridine nucleotide salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019365 pyridine nucleotide cycling Any process that generates a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base, from derivatives of them without de novo synthesis. GO:0019362 pyridine nucleotide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019362 pyridine nucleotide metabolism The chemical reactions and pathways involving a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base. GO:0019363 pyridine nucleotide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0019363 MetaCyc:PYRIDNUCSYN-PWY pyridine nucleotide anabolism|pyridine nucleotide synthesis|pyridine nucleotide formation|pyridine nucleotide biosynthesis The chemical reactions and pathways resulting in the formation of a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base. GO:0103041 thiosulfate-thioredoxin sulfurtransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103041 MetaCyc:RXN0-6385 Catalysis of the reaction: hydroxidodioxidosulfidosulfate + a reduced thioredoxin = sulfite + hydrogen sulfide + H+ + an oxidized thioredoxin. GO:0103042 4-hydroxy-L-threonine aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103042 MetaCyc:RXN0-6563|RHEA:28779 Catalysis of the reaction: 4-hydroxy-L-threonine <=> glycolaldehyde + glycine. GO:0103040 aldose sugar dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103040 MetaCyc:RXN0-6371 Catalysis of the reaction: H2O + an aldose + an oxidized electron acceptor = H+ + an aldonate + a reduced electron acceptor. GO:0103045 methione N-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103045 RHEA:44144|EC:2.3.1.1|MetaCyc:RXN0-6948 Catalysis of the reaction: L-methionine + acetyl-CoA = N-acetyl-L-methionine + coenzyme A + H+. GO:0103046 alanylglutamate dipeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103046 MetaCyc:RXN0-6981|EC:3.4.13.18 Catalysis of the reaction: L-alanyl-L-glutamate + H2O <=> L-alanine + L-glutamate. GO:0103043 5-phospho-alpha-D-ribosyl 1,2-cyclic phosphate phosphodiesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103043 MetaCyc:RXN0-6710|EC:3.1.4.55|RHEA:34795 Catalysis of the reaction: 5-phosphonato-alpha-D-ribose cyclic-1,2-phosphate + H2O <=> H+ + alpha-D-ribose 1,5-bisphosphate. GO:0103044 ribosomal protein S6 glutamate-glutamate ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103044 MetaCyc:RXN0-6726 Catalysis of the reaction: L-glutamate + ATP + a [protein] C-terminal L-glutamate = ADP + hydrogenphosphate + H+ + a [protein] with C-terminal alpha-L-glutamate-alpha-L-glutamate. GO:0103047 methyl beta-D-glucoside 6-phosphate glucohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103047 MetaCyc:RXN0-6994|EC:3.2.1.86 Catalysis of the reaction: methyl beta-D-glucoside 6-phosphate + H2O = beta-D-glucose 6-phosphate + methanol. GO:0103048 tRNA m2A37 methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103048 MetaCyc:RXN0-7007 Catalysis of the reaction: 2 S-adenosyl-L-methionine + an adenine37 in tRNA <=> S-adenosyl-L-homocysteine + L-methionine + 5'-deoxyadenosine + a 2-methyladenine37 in tRNA. GO:0103052 N3-methylcytosine demethylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103052 MetaCyc:RXN0-985 Catalysis of the reaction: N3-methylcytosine + O2 + 2-oxoglutarate <=> H+ + cytosine + carbon dioxide + formaldehyde + succinate. GO:0103053 1-ethyladenine demethylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103053 EC:1.14.11.33|RHEA:30299|MetaCyc:RXN0-986 Catalysis of the reaction: 1-ethyladenine + O2 + 2-oxoglutarate(2-) <=> adenine + carbon dioxide + acetaldehyde + succinate. GO:0103050 isobutyraldehyde reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103050 MetaCyc:RXN0-7119 Catalysis of the reaction: isobutanol + NADP <=> isobutyraldehyde + NADPH + H+. GO:0103051 N1-methyladenine demethylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103051 MetaCyc:RXN0-984 Catalysis of the reaction: 1-methyladenine + O2 + 2-oxoglutarate <=> adenine + carbon dioxide + formaldehyde + succinate. GO:0103056 gibberellin A53, 2-oxoglutarate:oxygen oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103056 RHEA:60800|MetaCyc:RXN1F-167 Catalysis of the reaction: gibberellin A53 + O2 + 2-oxoglutarate <=> gibberellin A44 diacid + carbon dioxide + succinate. GO:0103057 gibberellin A19, 2-oxoglutarate:oxygen oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103057 MetaCyc:RXN1F-169 Catalysis of the reaction: gibberellin A19 + O2 + 2-oxoglutarate <=> H+ + gibberellin A20 + 2 carbon dioxide + succinate. GO:0103054 gibberellin A12, 2-oxoglutarate:oxygen oxidoreductase activity (gibberellin A15-forming) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103054 RHEA:60776|MetaCyc:RXN1F-162 Catalysis of the reaction: gibberellin A12 + O2 + 2-oxoglutarate <=> gibberellin A15 + carbon dioxide + succinate. GO:0103055 gibberelli A15, 2-oxoglutarate:oxygen oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103055 RHEA:60780|MetaCyc:RXN1F-163 Catalysis of the reaction: gibberellin A15 + 2-oxoglutarate + O2 <=> gibberellin A24 + succinate + carbon dioxide + H2O. GO:0103058 kaempferol 3-glucoside 7-O-rhamnosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103058 MetaCyc:RXN1F-443 Catalysis of the reaction: kaempferol 3-O-glucoside + UDP-L-rhamnose <=> kaempferol-3-glucoside-7-rhamnoside + UDP. GO:0103059 UDP-L-rhamnose:kaempferol 3-O-rhamnosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103059 MetaCyc:RXN1F-474|RHEA:61164 Catalysis of the reaction: kaempferol oxoanion + UDP-L-rhamnose <=> H+ + kaempferol-3-rhamnoside + UDP(3-). GO:0103060 kaempferol 3-rhamnoside 7-O-rhamnosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103060 MetaCyc:RXN1F-475 Catalysis of the reaction: kaempferol-3-rhamnoside + UDP-L-rhamnose <=> kaempferol-3-rhamnoside-7-rhamnoside + UDP. GO:0103063 trans-keto-C61-meroacyl-AMP ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103063 MetaCyc:RXN1G-4143 Catalysis of the reaction: ATP(4-) + H2O + a trans-keto-C61-meroacyl-[acp] <=> diphosphoric acid + a trans-keto-meroacyl-adenylate + a holo-[acyl-carrier protein]. GO:0103064 inositol phosphorylceramide mannosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103064 RHEA:61496|MetaCyc:RXN3O-663 Catalysis of the reaction: GDP-alpha-D-mannose + an inositol-phospho-alpha hydroxyphytoceramide = H+ + GDP + a mannosyl-inositol-phospho-alpha hydroxyphytoceramide. GO:0103061 trans-methoxy-C60-meroacyl-AMP ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103061 MetaCyc:RXN1G-4141 Catalysis of the reaction: ATP(4-) + H2O + a trans-methoxy-C60-meroacyl-[acp] <=> diphosphoric acid + a trans-methoxy-meroacyl-adenylate + a holo-[acyl-carrier protein]. GO:0103062 cis-keto-C60-meroacyl-AMP ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103062 MetaCyc:RXN1G-4142 Catalysis of the reaction: ATP(4-) + H2O + a cis-keto-C60-meroacyl-[acp] <=> diphosphoric acid + a cis-keto-meroacyl-adenylate + a holo-[acyl-carrier protein]. GO:0103067 4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-dehydrogenase (decarboxylating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103067 RHEA:33447|MetaCyc:RXN66-23|EC:1.1.1.170 Catalysis of the reaction: 4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol + NAD(P) = 5alpha-cholesta-8-en-3-one + carbon dioxide + NAD(P)H. GO:0103068 leukotriene C4 gamma-glutamyl transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103068 EC:2.3.2.2|MetaCyc:RXN66-336 Catalysis of the reaction: leukotriene C4 + a standard alpha amino acid = leukotriene D4 + an (gamma-L-glutamyl)-L-amino acid. GO:0103066 4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-oxidoreductase (decarboxylating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103066 MetaCyc:RXN66-18|EC:1.1.1.170 Catalysis of the reaction: 4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol + NAD(P) = 4alpha-methyl-5alpha-cholesta-8-en-3-one + carbon dioxide + NAD(P)H. GO:0103069 17-hydroxyprogesterone 21-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103069 MetaCyc:RXN66-356|RHEA:50308 Catalysis of the reaction: 17alpha-hydroxyprogesterone + O2 + reduced [NADPH--hemoprotein reductase] = 11-deoxycortisol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]. GO:0103071 2-hydroxy-3-methyl-branched 2,3,4-saturated fatty acyl-CoA lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103071 MetaCyc:RXN66-471 Catalysis of the reaction: a 2-hydroxy-3-methyl-branched 2,3,4-saturated fatty acyl-CoA <=> formyl-CoA + a 2-methyl branched 2,3,4-saturated fatty aldehyde. GO:0103074 glucose-6-phosphate 3-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103074 EC:1.1.1.361|MetaCyc:RXN8J2-136|RHEA:37547 Catalysis of the reaction: NAD + D-glucopyranose 6-phosphate = NADH + H+ + 3-dehydro-D-glucose 6-phosphate. GO:0103075 indole-3-pyruvate monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103075 EC:1.14.13.168|RHEA:34331|MetaCyc:RXNDQC-2 Catalysis of the reaction: 3-(indol-3-yl)pyruvate + NADPH + O2 + H+ <=> indole-3-acetate + carbon dioxide + NADP + H2O. GO:0103072 straight chain (R)-2-hydroxy fatty acyl-CoA lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103072 MetaCyc:RXN66-475 Catalysis of the reaction: a (R)-2-hydroxy even numbered straight chain 2,3,4-saturated fatty acyl CoA = formyl-CoA + an odd numbered straight chain 2,3,4-saturated fatty aldehyde. GO:0103073 anandamide amidohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103073 MetaCyc:RXN6666-2|EC:3.5.1.99|RHEA:26136 Catalysis of the reaction: anandamide + H2O <=> arachidonate + ethanolaminium(1+). GO:0103078 quercetin 3-rhamnoside 7-O-rhamnosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103078 MetaCyc:RXNQT-4162|RHEA:61184 Catalysis of the reaction: H+ + quercetin 3-O-rhamnoside + UDP-L-rhamnose <=> quercetin-3-rhamnoside-7-rhamnoside + UDP. GO:0103079 2-(3'-methylthio)propylmalate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103079 RHEA:25605|MetaCyc:RXNQT-4163 Catalysis of the reaction: 5-methylthio-2-oxopentanoate + acetyl-CoA + H2O <=> H+ + 2-(3-methylthiopropyl)malate + coenzyme A. GO:0103077 quercetin 3-glucoside 7-O-rhamnosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103077 RHEA:61188|MetaCyc:RXNQT-4161 Catalysis of the reaction: quercetin-3-glucoside + UDP-L-rhamnose <=> quercetin-3-O-glucoside-7-O-rhamnoside + UDP. GO:0103081 methylthiopropylmalate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103081 MetaCyc:RXNQT-4165 Catalysis of the reaction: 3-(3'-methylthio)propylmalate <=> H+ + 2-oxo-6-methylthiohexanoate + carbon dioxide. GO:0103082 2-(4'-methylthio)butylmalate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103082 MetaCyc:RXNQT-4166 Catalysis of the reaction: 2-oxo-6-methylthiohexanoate + acetyl-CoA + H2O <=> H+ + 2-(4'-methylthio)butylmalate + coenzyme A. GO:0103080 methylthiopropylmalate isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103080 RHEA:50644|MetaCyc:RXNQT-4164 Catalysis of the reaction: 2-(3-methylthiopropyl)malate(2-) <=> 3-(3'-methylthio)propylmalate. GO:0103001 dimethylsulfoxide oxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103001 MetaCyc:RXN-9767|RHEA:57956 Catalysis of the reaction: dimethyl sulfoxide + O2 + NADPH + H+ <=> sulfonyldimethane + H2O + NADP. GO:0103002 16-hydroxypalmitate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103002 MetaCyc:RXN-9802 Catalysis of the reaction: 16-hydroxypalmitate + NADP <=> H+ + 16-oxo-palmitate + NADPH. GO:0103000 UDP-glucose:4-hydroxylamino-2,6-dinitrotoluene-O-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103000 MetaCyc:RXN-9748 Catalysis of the reaction: UDP-alpha-D-glucose + 4-hydroxylamino-2,6-dinitrotoluene <=> 4-hydroxylamino-2,6-dinitrotoluene-O-glucoside + UDP + H+. GO:0103005 9,10-epoxystearate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103005 MetaCyc:RXN-9806 Catalysis of the reaction: 9,10-epoxystearate + H2O <=> (9R,10S)-dihydroxystearate. GO:0103006 9,10-dihydroxystearate hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103006 MetaCyc:RXN-9807 Catalysis of the reaction: H+ + (9R,10S)-dihydroxystearate + O2 + NADPH <=> 9,10,18-trihydroxystearate + H2O + NADP. GO:0103003 oleate peroxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103003 MetaCyc:RXN-9804 Catalysis of the reaction: oleate + a lipid hydroperoxide <=> 9,10-epoxystearate + a lipid alcohol. GO:0103004 9,10-epoxystearate hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103004 MetaCyc:RXN-9805 Catalysis of the reaction: H+ + 9,10-epoxystearate + O2 + NADPH <=> 9,10-epoxy-18-hydroxystearate + H2O + NADP. GO:0103009 3-chlorotoluene monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103009 MetaCyc:RXN-9908 Catalysis of the reaction: H+ + 3-chlorotoluene + NADH + O2 <=> 3-chlorobenzyl alcohol + NAD + H2O. GO:0103007 indole-3-acetate carboxyl methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103007 MetaCyc:RXN-9825|RHEA:36131|EC:2.1.1.278 Catalysis of the reaction: indole-3-acetate + S-adenosyl-L-methionine <=> methyl (indol-3-yl)acetate + S-adenosyl-L-homocysteine. GO:0103008 4-chloro-2-methylphenoxyacetate oxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103008 MetaCyc:RXN-9864 Catalysis of the reaction: 4-chloro-2-methylphenoxyacetate + 2-oxoglutarate + O2 <=> 4-chloro-2-methylphenol + 2-oxo monocarboxylic acid anion + succinate + carbon dioxide. GO:0103012 ferredoxin-thioredoxin reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103012 MetaCyc:RXN-9944|RHEA:42336|EC:1.8.7.2 ferredoxin:thioredoxin reductase activity Catalysis of the reaction: 2 H+ + 2 a reduced ferredoxin + an oxidized thioredoxin = 2 an oxidized ferredoxin + a reduced thioredoxin, involving a 4Fe-4S cluster and an adjacent active-site disulfide. GO:0103010 gibberellin A53,2-oxoglutarate:oxygen oxidoreductase activity (GA97-forming) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103010 MetaCyc:RXN-991 Catalysis of the reaction: gibberellin A53 + 2-oxoglutarate + O2 = gibberellin A97 + succinate + carbon dioxide. GO:0103011 mannosylfructose-phosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103011 RHEA:26039|EC:2.4.1.246|MetaCyc:RXN-9935 Catalysis of the reaction: GDP-alpha-D-mannose + beta-D-fructofuranose 6-phosphate <=> mannosylfructose-phosphate + GDP. GO:0103016 tRNA-specific 2-thiouridylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103016 MetaCyc:RXN0-2023 Catalysis of the reaction: ATP + H+ + a tRNA uridine34 + a [TusE sulfur carrier protein]-S-sulfanylcysteine = AMP + diphosphoric acid + a tRNA 2-thiouridine34 + a [TusE sulfur carrier protein]-L-cysteine. GO:0103014 beta-keto ester reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103014 MetaCyc:RXN0-1941 Catalysis of the reaction: ethyl-(2R)-methyl-(3S)-hydroxybutanoate + NADP = ethyl-2-methylacetoacetate + NADPH + H+. GO:0103015 4-amino-4-deoxy-L-arabinose transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103015 RHEA:35371|MetaCyc:RXN0-2001|EC:2.4.2.43 Catalysis of the reaction: (Kdo)2-lipid A + 2 4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,poly-cis-undecaprenyl phosphate = (beta-L-Ara4N)2-(KDO)2-lipid A + 2 ditrans,polycis-undecaprenyl phosphate. GO:0103019 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0103019 GO:0103020 1-deoxy-D-xylulose kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103020 RHEA:27990|MetaCyc:RXN0-382 Catalysis of the reaction: 1-deoxy-D-xylulose + ATP <=> H+ + 1-deoxy-D-xylulose 5-phosphate + ADP. GO:0103023 ITPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103023 MetaCyc:RXN0-5073|RHEA:28330 Catalysis of the reaction: ITP + H2O <=> H+ + IDP + hydrogenphosphate. GO:0103024 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0103024 GO:0103027 FMN phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103027 MetaCyc:RXN0-5187 Catalysis of the reaction: FMN + H2O = riboflavin + hydrogenphosphate. GO:0103028 murein hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103028 MetaCyc:RXN0-5190 Catalysis of the reaction: a peptidoglycan dimer (generic) = a lipid II + GlcNAc-1,6-anhydro-MurNAc-pentapeptide. GO:0103025 alpha-amylase activity (releasing maltohexaose) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103025 MetaCyc:RXN0-5181|EC:3.2.1.1 Catalysis of the reaction: n H2O + a 1,4-alpha-D-glucan = alpha-maltohexaose + a 1,4-alpha-D-glucan. GO:0103026 fructose-1-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103026 RHEA:35603|MetaCyc:RXN0-5186 Catalysis of the reaction: beta-D-fructofuranose 1-phosphate + H2O <=> beta-D-fructofuranose + hydrogenphosphate. CHEBI:140297 4'-O-demethylsordarin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_140297 CHEBI:140294 5'-triphosphoadenylyl-(2'->5')-adenosine(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140294 OBO:go/extensions/ro_pending#results_in_transport_through obsolete results_in_transport_through biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/go/extensions/ro_pending#results_in_transport_through CHEBI:139296 D-alanyl-AMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_139296 GO:0103030 ethylglyoxal reductase (NADH-dependent, hydroxyacetone-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103030 MetaCyc:RXN0-5213|RHEA:35615 Catalysis of the reaction: H+ + methylglyoxal + NADH = hydroxyacetone + NAD. GO:0103031 L-Ala-D/L-Glu epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103031 RHEA:28394|MetaCyc:RXN0-5228 Catalysis of the reaction: L-alanyl-D-glutamate = L-alanyl-L-glutamate. GO:0103035 NAD(P)H:methyl-1,4-benzoquinone oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103035 MetaCyc:RXN0-5387 Catalysis of the reaction: 3 H+ + methyl-1,4-benzoquinone + NADPH = methyl-1,4-benzoquinol + NADP. GO:0103032 tartronate semialdehyde reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103032 MetaCyc:RXN0-5289|RHEA:18845 Catalysis of the reaction: D-glycerate + NAD <=> H+ + 2-hydroxy-3-oxopropanoate + NADH. GO:0103033 beta-galactosidase activity (lactose isomerization) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103033 MetaCyc:RXN0-5363 Catalysis of the reaction: alpha-lactose = beta-(1->6)-galactobiose. GO:0103039 protein methylthiotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103039 RHEA:37087|MetaCyc:RXN0-6366|EC:2.8.4.4 Catalysis of the reaction: 2 S-adenosyl-L-methionine + a [ribosomal protein S12] L-aspartate89 + a sulfurated [sulfur carrier] + a reduced electron acceptor = S-adenosyl-L-homocysteine + L-methionine + 5'-deoxyadenosine + 2 H+ + a [ribosomal protein S12] 3-methylthio-L-aspartate89 + an unsulfurated [sulfur carrier] + an oxidized electron acceptor. GO:0103036 NADH:menaquinone oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103036 MetaCyc:RXN0-5388 Catalysis of the reaction: 5 H+ + NADH + a menaquinone <=> 4 H+ + NAD + a menaquinol. GO:0103037 L-glyceraldehyde 3-phosphate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103037 MetaCyc:RXN0-5410 Catalysis of the reaction: sn-glycerol 3-phosphate + NADP = H+ + L-glyceraldehyde 3-phosphate + NADPH. CHEBI:140286 deoxyribonucleoside 5'-methylphosphate residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140286 CHEBI:140284 deoxyribonucleotide residue(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_140284 GO:0010929 positive regulation of auxin mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010929 positive regulation of auxin mediated signalling pathway Any process that increases the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin. GO:0044261 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044261 GO:0044262 cellular carbohydrate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044262 cellular carbohydrate metabolism|main pathways of carbohydrate metabolic process|main pathways of carbohydrate metabolism The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells. GO:0010927 cellular component assembly involved in morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010927 The cellular component assembly that is part of the initial shaping of the component during its developmental progression. GO:0044260 cellular macromolecule metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044260 cellular biopolymer metabolic process|cellular macromolecule metabolism The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells. GO:0010928 regulation of auxin mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010928 regulation of auxin mediated signalling pathway Any process that modulates the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin. CHEBI:23557 dTDP-sugar biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23557 GO:0044269 glycerol ether catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044269 glycerol ether degradation|glycerol ether breakdown|glycerol ether catabolism The chemical reactions and pathways resulting in the breakdown of glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol. GO:0010921 regulation of phosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010921 Any process that modulates the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate. GO:0010922 positive regulation of phosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010922 Any process that increases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate. GO:0044267 cellular protein metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044267 cellular protein metabolism The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes cellular protein modification. GO:0044268 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044268 GO:0010920 negative regulation of inositol phosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010920 negative regulation of inositol phosphate biosynthesis Any process that decreases the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached. GO:0044265 cellular macromolecule catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044265 cellular macromolecule degradation|cellular macromolecule breakdown|cellular biopolymer catabolic process|cellular macromolecule catabolism The chemical reactions and pathways resulting in the breakdown of a macromolecule, any large molecule including proteins, nucleic acids and carbohydrates, as carried out by individual cells. GO:0010925 positive regulation of inositol-polyphosphate 5-phosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010925 Any process that increases the rate or frequency of inositol-polyphosphate 5-phosphatase activity, the catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate. GO:0010926 obsolete anatomical structure formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010926 anatomical structure formation OBSOLETE. The process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structure is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. GO:0044266 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044266 GO:0010923 negative regulation of phosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010923 Any process that decreases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate. GO:0044263 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044263 GO:0044264 cellular polysaccharide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044264 cellular glycan metabolism|cellular glycan metabolic process|cellular polysaccharide metabolism The chemical reactions and pathways involving polysaccharides, polymers of more than 10 monosaccharide residues joined by glycosidic linkages, as carried out by individual cells. GO:0010924 regulation of inositol-polyphosphate 5-phosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010924 Any process that modulates the rate or frequency of inositol-polyphosphate 5-phosphatase activity, the catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate. UBERON:0004781 gall bladder lamina propria biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004781 lamina propria of gallbladder|gall bladder lamina propria mucosa|lamina propria of gall bladder|lamina propria mucosa of gallbladder|biliary lamina propria|gallbladder lamina propria|gallbladder lamina propria mucosa|lamina propria mucosa of gall bladder A lamina propria that is part of a gallbladder [Automatically generated definition]. UBERON:0004782 gastrointestinal system serosa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004782 gastrointestinal system serous membrane|serosa of gastrointestinal system|serous membrane of digestive system|digestive system serosa|serosa of digestive system|digestive system serous membrane|serous membrane of gastrointestinal system A serous membrane that is part of a digestive system [Automatically generated definition]. UBERON:0004780 gastrointestinal system lamina propria biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004780 A lamina propria that is part of a gastrointestinal system. GO:0009930 longitudinal side of cell surface biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009930 The side of the cell parallel to the zygotic axis. GO:0009931 calcium-dependent protein serine/threonine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009931 Calcium-dependent catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate. UBERON:0004789 larynx mucous gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004789 mucous gland of larynx A mucous gland that is part of a larynx [Automatically generated definition]. GO:0009932 cell tip growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009932 Growth that occurs specifically at the tip of a cell. GO:0009933 meristem structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009933 meristem organisation|meristem organization Organization of a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation, thereby effecting growth and development of a plant by giving rise to more meristem or specialized tissue. GO:0009934 regulation of meristem structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009934 regulation of meristem organisation|regulation of meristem organization Any process that modulates the frequency, rate or extent of meristem organization. UBERON:0004787 urethra urothelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004787 urothelium of urethra|uroepithelium of urethra|urethra uroepithelium An urothelium that is part of a urethra [Automatically generated definition]. UBERON:0004788 kidney pelvis urothelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004788 transitional epithelium of kidney pelvis|pelvic urothelium|kidney pelvis transitional epithelium|transitional epithelium of renal pelvis|renal pelvis urothelium|urothelium of kidney pelvis|uroepithelium of pelvis of ureter|renal pelvis transitional epithelium|uroepithelium of kidney pelvis|pelvis of ureter urothelium|urothelium of pelvis of ureter|kidney pelvis uroepithelium|uroepithelium of renal pelvis|pelvis of ureter uroepithelium|urothelium of renal pelvis|renal pelvis uroepithelium the epithelial lining of the luminal space of the kidney pelvis GO:0009935 obsolete nutrient import biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009935 nutrient import|nutrient uptake OBSOLETE. The directed movement of nutrients into a cell or organelle. UBERON:0004785 respiratory system mucosa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004785 laryngeal mucous membrane|mucosa of organ of respiratory system|respiratory mucosa|mucous membrane of apparatus respiratorius|mucosa of respiratory system|mucosa of apparatus respiratorius|mucous membrane of respiratory system|mucosa of organ of apparatus respiratorius|respiratory system mucosa of organ|apparatus respiratorius mucosa|respiratory system mucous membrane|apparatus respiratorius mucosa of organ|respiratory tract mucosa|apparatus respiratorius mucous membrane the mucous membrane lining the respiratory tract GO:0009936 obsolete expansin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009936 expansin OBSOLETE. A group of proteins located within the cell walls of plants, both dicots and grasses, that play an essential role in loosening cell walls during cell growth. They are hydrophobic, non glycosylated proteins of about 30kDa. UBERON:0004786 gastrointestinal system mucosa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004786 mucosa of gut|gut mucuous membrane|digestive tract mucosa|gut mucosa A mucosa that is part of a gastrointestinal system. GO:0009937 regulation of gibberellic acid mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009937 regulation of gibberellic acid mediated signalling Any process that modulates the frequency, rate or extent of gibberellic acid mediated signaling. GO:0009938 negative regulation of gibberellic acid mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009938 downregulation of gibberellic acid mediated signaling|down-regulation of gibberellic acid mediated signaling|negative regulation of gibberellic acid mediated signalling|inhibition of gibberellic acid mediated signaling|down regulation of gibberellic acid mediated signaling Any process that stops, prevents, or reduces the frequency, rate or extent of gibberellic acid mediated signaling activity. UBERON:0004783 gall bladder serosa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004783 tunica serosa (vesica biliaris)|biliary serosa|gallbladder serosa|gallbladder serous membrane|serous coat of gallbladder|serous membrane of gall bladder|gall bladder serous membrane|serosa of gall bladder|serosa of gallbladder|serous membrane of gallbladder|tunica serosa vesicae biliaris A serous membrane that is part of a gallbladder [Automatically generated definition]. UBERON:0004784 heart ventricle wall biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004784 wall of cardiac ventricle|wall of ventricle|ventricle of heart anatomical wall|cardiac ventricle anatomical wall|wall of lower chamber of heart|anatomical wall of lower chamber of heart|lower chamber of heart wall|ventricular wall|anatomical wall of heart ventricle|lower chamber of heart anatomical wall|wall of heart ventricle|wall of ventricle of heart|cardiac ventricle wall|heart ventricle anatomical wall|anatomical wall of ventricle of heart|ventricle of heart wall|anatomical wall of cardiac ventricle An anatomical wall that is part of a cardiac ventricle [Automatically generated definition]. GO:0009939 positive regulation of gibberellic acid mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009939 up regulation of gibberellic acid mediated signaling|activation of gibberellic acid mediated signaling|stimulation of gibberellic acid mediated signaling|up-regulation of gibberellic acid mediated signaling|positive regulation of gibberellic acid mediated signalling|upregulation of gibberellic acid mediated signaling Any process that activates or increases the frequency, rate or extent of gibberellic acid mediated signaling activity. GO:0044272 sulfur compound biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044272 sulfur compound anabolism|sulfur compound synthesis|sulfur compound formation|sulfur compound biosynthesis|sulfur biosynthesis|sulfur biosynthetic process The chemical reactions and pathways resulting in the formation of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione. GO:0044273 sulfur compound catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044273 sulfur compound catabolism|sulfur catabolic process|sulfur catabolism|sulfur compound degradation|sulfur compound breakdown The chemical reactions and pathways resulting in the breakdown of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione. GO:0044270 cellular nitrogen compound catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044270 nitrogen compound degradation|nitrogen compound breakdown|nitrogen compound catabolism The chemical reactions and pathways resulting in the breakdown of organic and inorganic nitrogenous compounds. GO:0010938 cytoplasmic microtubule depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010938 The removal of tubulin heterodimers from one or both ends of a cytoplasmic microtubule. GO:0044271 cellular nitrogen compound biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044271 nitrogen compound biosynthesis|nitrogen compound anabolism|nitrogen compound synthesis|nitrogen compound formation The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds. GO:0010939 regulation of necrotic cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010939 Any process that modulates the rate, frequency or extent of necrotic cell death. Necrotic cell death is a cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents. UBERON:0004769 diaphysis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004769 long bone diaphysis|body of long bone|shaft of long bone Subdivision of long bone which forms the part of the bone between the two epiphyses, excluding the metaphyses[FMA,modified]. GO:0010932 regulation of macrophage tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010932 Any process that modulates the frequency, rate, or extent of macrophage tolerance induction. GO:0010933 positive regulation of macrophage tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010933 Any process that increases the frequency, rate, or extent of B cell tolerance induction. GO:0044278 cell wall disruption in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044278 A process carried out by an organism that results in the breakdown of the cell wall of a second organism. GO:0010930 negative regulation of auxin mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010930 negative regulation of auxin mediated signalling pathway Any process that decreases the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin. GO:0010931 macrophage tolerance induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010931 A process involving any mechanism for tolerance induction in macrophages. GO:0044279 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044279 GO:0010936 negative regulation of macrophage cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010936 Any process that decreases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0044276 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044276 GO:0044277 cell wall disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044277 cellular cell wall disassembly A process that results in the breakdown of the cell wall. GO:0010937 regulation of cytoplasmic microtubule depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010937 Any process that modulates the frequency, rate or extent of cytoplasmic microtubule depolymerization. GO:0044274 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044274 GO:0010934 macrophage cytokine production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0010934 The appearance of a macrophage cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0044275 cellular carbohydrate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044275 cellular carbohydrate degradation|cellular carbohydrate breakdown|cellular carbohydrate catabolism The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells. GO:0010935 regulation of macrophage cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010935 Any process that modulates the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. UBERON:0004770 articular system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004770 joint system|set of all joints of body|set of joints of body|set of all joints Anatomical system that consists of all the joints of the body. UBERON:0004771 posterior nasal aperture biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004771 posterior choana|posterior naris|choana|internal naris|nasopharyngeal naris|choanae|posterior nasal apperture Opening/conduit between the nasal cavity and the nasopharynx[AAO] The choanae are separated by the vomer[WP]. CHEBI:1135 2-hydroxy-6-(2-hydroxyphenyl)-6-oxo-cis,cis-hexa-2,4-dienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_1135 GO:0009940 amino-terminal vacuolar sorting propeptide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009940 Interacting selectively and non-covalently with an amino terminal propeptide, which functions as a sorting signal to sort away the soluble vacuolar protein from Golgi to lytic vacuole via clathrin-coated vesicles. GO:0009941 chloroplast envelope biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009941 The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space. GO:0009942 longitudinal axis specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009942 longitudinal axis determination|apical-basal pattern specification The establishment, maintenance and elaboration of the longitudinal axis. In plants, this is the axis that runs from the shoot to the root. GO:0009943 adaxial/abaxial axis specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009943 adaxial/abaxial determination The establishment, maintenance and elaboration of the adaxial / abaxial axis. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure. UBERON:0004778 larynx submucosa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004778 laryngeal submucosa|submucosa of larynx A submucosa that is part of a larynx [Automatically generated definition]. GO:0009944 polarity specification of adaxial/abaxial axis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009944 The process resulting in the establishment of polarity along the adaxial/abaxial axis. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure. UBERON:0004779 respiratory system lamina propria biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004779 lamina propria of apparatus respiratorius|lamina propria mucosa of respiratory system|respiratory system lamina propria mucosa|lamina propria mucosa of apparatus respiratorius|lamina propria of respiratory system|apparatus respiratorius lamina propria mucosa|apparatus respiratorius lamina propria A lamina propria that is part of a respiratory system [Automatically generated definition]. GO:0009945 radial axis specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009945 The establishment, maintenance and elaboration of an axis that initiates at a point and radiates outward from the point. GO:0009946 proximal/distal axis specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009946 proximodistal axis specification|proximal/distal axis determination The establishment, maintenance and elaboration of the proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end). UBERON:0004777 respiratory system submucosa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004777 apparatus respiratorius submucosa|submucosa of apparatus respiratorius|submucosa of respiratory system A submucosa that is part of a respiratory system [Automatically generated definition]. GO:0009947 centrolateral axis specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009947 centrolateral axis determination|mediolateral axis specification The establishment, maintenance and elaboration of the centrolateral axis. In plants, this axis is duplicated and runs from the midrib to the margin of the leaf. GO:0009948 anterior/posterior axis specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009948 anterior/posterior axis determination The establishment, maintenance and elaboration of the anterior/posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism. GO:0009949 polarity specification of anterior/posterior axis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009949 Any process resulting in the establishment of polarity along the anterior/posterior axis. UBERON:0004772 eyelid tarsus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004772 tarsus palpebralis|tarsi|tarsal plate|tarsal plate of eyelid|eyelid tarsi The tarsi (tarsal plates) are two comparatively thick, elongated plates of dense connective tissue, about 2.5 cm. in length; one is found in each eyelid, and contributes to its form and support. They directly abut the lid margins. GO:0009918 sterol delta7 reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009918 MetaCyc:RXN-707 sterol delta-7 reductase activity Catalysis of the reaction: 5-dehydroepisterol = 24-methylenecholesterol. GO:0010907 positive regulation of glucose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010907 positive regulation of glucose metabolism Any process that increases the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. GO:0044283 small molecule biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044283 small molecule biosynthesis The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule. GO:0009919 obsolete cytokinesis (sensu Viridiplantae) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009919 cytokinesis (sensu Viridiplantae) OBSOLETE. The division of a cell into two daughter cells with cell walls. GO:0044284 mitochondrial crista junction biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044284 cristae junction|crista junction A tubular structure of relatively uniform size that connects a mitochondrial crista to the mitochondrial inner boundary membrane. GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010908 Any process that modulates the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis. Heparan sulfate proteoglycan biosynthetic processes are the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues. GO:0044281 small molecule metabolic process biolink:BiologicalProcess go-plus goslim_generic|goslim_flybase_ribbon|goslim_chembl|goslim_metagenomics http://purl.obolibrary.org/obo/GO_0044281 small molecule metabolism The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule. GO:0010905 negative regulation of UDP-glucose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010905 negative regulation of UDP-glucose catabolism Any process that decreases the rate, frequency or extent of UDP-glucose catabolism. UDP-glucose catabolic processes are the chemical reactions and pathways resulting in the breakdown of UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate. GO:0044282 small molecule catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0044282 small molecule catabolism The chemical reactions and pathways resulting in the breakdown of small molecules, any low molecular weight, monomeric, non-encoded molecule. GO:0010906 regulation of glucose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010906 regulation of glucose metabolism Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. CHEBI:23530 cytokinin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23530 GO:0044280 subplasmalemmal coating biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044280 NIF_Subcellular:sao1938587839 Electron dense material observed coating the cytoplasmic face of the plasma membrane in certain regions of a neuron, e.g., the axon initial segment; the nodal membrane at the Node of Ranvier. UBERON:0004758 salt gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004758 An organ for excreting excess salts. It is found in elasmobranchs, seabirds, and some reptiles.[WP]. GO:0010909 positive regulation of heparan sulfate proteoglycan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010909 Any process that increases the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis. Heparan sulfate proteoglycan biosynthetic processes are the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues. UBERON:0004759 cranial salt gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004759 A salt gland located in the cranium or head region. GO:0010900 negative regulation of phosphatidylcholine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010900 Any process that decreases the rate, frequency or extent of phosphatidylcholine catabolism. Phosphatidylcholine catabolic processes are the chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. CHEBI:1109 2-hexaprenyl-6-methoxyphenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_1109 GO:0044289 mitochondrial inner-outer membrane contact site biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044289 contact site|bridge contact site Sites of close apposition of the inner and outer mitochondrial membrane. GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010903 negative regulation of VLDL remodeling Any process that decreases the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid. GO:0044287 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044287 GO:0044288 puncta adhaerentia biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044288 NIF_Subcellular:sao257629430 A small version of the zonula adherens type junction, characterized by a symmetrical adherent point between two cells. GO:0010904 regulation of UDP-glucose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010904 regulation of UDP-glucose catabolism Any process that modulates the rate, frequency or extent of UDP-glucose catabolism. UDP-glucose catabolic processes are the chemical reactions and pathways resulting in the breakdown of UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate. GO:0010901 regulation of very-low-density lipoprotein particle remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010901 regulation of VLDL remodeling Any process that modulates the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid. GO:0044285 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0044285 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010902 positive regulation of VLDL remodeling Any process that increases the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid. GO:0044286 peg and socket contact biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044286 NIF_Subcellular:sao1943947957 ball and socket contact A cell-cell contact zone that consists of membrane invaginations extending from either cell, which contain tight-, gap-, and adherens junctions. Peg and socket contacts form between endothelial cells and pericytes, and between lens fiber cells. UBERON:0004760 gland of anal canal biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004760 rectal gland|gland of anal canal|anal sac|anal gland|gland of anus A gland that is part of an anal canal [Automatically generated definition]. CHEBI:1107 2-hexaprenyl-6-hydroxyphenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_1107 GO:0009910 negative regulation of flower development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009910 down regulation of flower development|inhibition of flower development|down-regulation of flower development|downregulation of flower development Any process that stops, prevents, or reduces the frequency, rate or extent of flower development. UBERON:0004767 vomerine tooth biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004767 A tooth that is on the vomer. GO:0009911 positive regulation of flower development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009911 upregulation of flower development|stimulation of flower development|up-regulation of flower development|activation of flower development|up regulation of flower development Any process that activates or increases the frequency, rate or extent of flower development. UBERON:0004768 bone of lower jaw biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004768 lower jaw bone Any bone that is part of the lower jaw skeleton. This includes (when present): the dentary/mandible, the articular, the splenial, the suprangular GO:0009912 auditory receptor cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009912 auditory hair cell fate commitment The process in which the cellular identity of auditory hair cells is acquired and determined. UBERON:0004765 skeletal element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004765 Organ consisting of skeletal tissue. Encompasses whole bones, fused bones, cartilaginious elements, teeth, dermal denticles. UBERON:0004766 cranial bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004766 cranium bone A bone that is part of a cranium. GO:0009913 epidermal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009913 hypodermal cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an epidermal cell, any of the cells making up the epidermis. GO:0009914 hormone transport biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0009914 The directed movement of hormones into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UBERON:0004763 endochondral bone tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004763 Replacement bone tissue that forms within cartilage[VSAO, modified]. UBERON:0004764 intramembranous bone tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004764 Bone tissue that forms directly within mesenchyme, and does not replace other tissues[TAO]. Intramembranous ossification is the formation of bone in which osteoblasts secrete a collagen-proteoglycan matrix that binds calcium salts and becomes calcified[GO]. Intramembranous ossification is the way flat bones and the shell of a turtle are formed[GO]. Unlike endochondral ossification, cartilage is not present during intramembranous ossification[WP]. GO:0009915 phloem sucrose loading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009915 The process of loading sucrose into the sieve tube or companion cell of the phloem for long distance transport from source to sink. UBERON:0004761 cartilaginous neurocranium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004761 cartilaginous skull|cartilaginous chondocranium|chondocranium|cartiligionous skeletal structure of skull|embryonic chondocranium|neurocranium The primitive cartilagionous skeletal structure of the fetal skull that grows to envelop the rapidly growing embyonic brain. In humans, the chondrocranium begins forming at 28 days from mesenchymal condensations and is fully formed between week 7 and 9 of fetal development. While the majority of the chondrocranium is succeeded by the bony skull in most higher vertebrates, some components do persist into adulthood.[1] In Cartilagious fishes and Agnathans, the chondrocranium persist throughout life.[2] Embryologically, the chondrocranium represent the basal cranial structure, and lay the base for the formation of the endocranium in higher vertebrates[WP]. GO:0009916 alternative oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009916 Catalysis of the oxidation of ubiquinol by diverting electrons from the standard electron transfer chain, transferring them from ubiquinol to oxygen and generating water as the product. GO:0009917 sterol 5-alpha reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009917 Catalysis of the removal of a C-5 double bond in the B ring of a sterol. GO:0010918 positive regulation of mitochondrial membrane potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010918 elevation of mitochondrial membrane potential Any process that activates or increases the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. GO:0044294 dendritic growth cone biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044294 NIF_Subcellular:sao1594955670 dendrite growth cone The migrating motile tip of a growing nerve cell dendrite. GO:0009929 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009929 GO:0010919 regulation of inositol phosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010919 regulation of inositol phosphate biosynthesis Any process that modulates the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached. GO:0044295 axonal growth cone biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044295 NIF_Subcellular:sao203987954|NIF_Subcellular:sao1594955670 axon growth cone The migrating motile tip of a growing nerve cell axon. GO:0010916 negative regulation of very-low-density lipoprotein particle clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010916 negative regulation of VLDL particle clearance|negative regulation of VLDL clearance Any process that decreases the rate, frequency or extent of very-low-density lipoprotein particle clearance. Very-low-density lipoprotein particle clearance is the process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. GO:0044292 dendrite terminus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044292 NIF_Subcellular:sao28175134 dendrite terminal specialization|dendrite terminal|terminal specialization of a dendrite|terminal specialization A structure at the distal end of a dendrite adapted to carry out a specific function, e.g. dendriole. GO:0010917 negative regulation of mitochondrial membrane potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010917 reduction of mitochondrial membrane potential Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. GO:0044293 dendriole biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044293 NIF_Subcellular:sao28175134|NIF_Subcellular:sao295057932 Small dendrites that makes up a brush structure found as the terminal specialization of a dendrite of a unipolar brush cell (UBC). GO:0044290 mitochondrial intracristal space biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044290 NIF_Subcellular:sao508958414 The space bounded by the mitochondrial cristae membranes, continuous with the intermembrane space. UBERON:0004749 blastodisc biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004749 germ disc|embryonic disc|gastrodisk|germinal disc A small, circular, white spot (approximately 2-3 mm across) on the surface of the yellow yolk of an egg that has been laid. The nucleus of the egg is in the germinal disc. GO:0044291 cell-cell contact zone biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044291 NIF_Subcellular:sao1299635018 cell cell contact zone Extended zone of intimate apposition between two cells containing one or more types of intercellular junctions, e.g., the intercalated disk of muscle. GO:0010910 positive regulation of heparan sulfate proteoglycan biosynthesis by positive regulation of epimerase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010910 Any process that increases the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis by an increase in epimerase activity. This epimerase activity catalyzes the reaction that converts D-glucuronate into its diastereoisomer in heparan sulfate. GO:0010911 regulation of isomerase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010911 Any process that modulates the activity of an isomerase. An isomerase catalyzes the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5. GO:0010914 positive regulation of sterigmatocystin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010914 Any process that increases the rate, frequency, or extent of sterigmatocystin biosynthesis. Sterigmatocystin biosynthetic processes are the chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds. GO:0044298 cell body membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044298 cell soma membrane The plasma membrane of a cell that bears surface projections such as axons, dendrites, cilia, or flagella, excluding the plasma membrane on cell projections. GO:0044299 C-fiber biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044299 NIF_Subcellular:nlx_subcell_20090210 C-fibre The axon of a dorsal root ganglion cell that are responsive to pain and temperature. C-fibers are small in diameter (0.2-1.5 um) and unmyelinated. GO:0010915 regulation of very-low-density lipoprotein particle clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010915 regulation of VLDL particle clearance|regulation of VLDL clearance Any process that modulates the rate, frequency or extent of very-low-density lipoprotein particle clearance. Very-low-density lipoprotein particle clearance is the process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. GO:0010912 positive regulation of isomerase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010912 Any process that increases the activity of an isomerase. An isomerase catalyzes the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5. GO:0044296 dendritic tuft biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044296 NIF_Subcellular:sao1340260079 dendrite tuft The terminal specialization found in some types of dendrites which consists of numerous small terminal branches, giving the dendrite a tufted appearance. GO:0044297 cell body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0044297 Wikipedia:Cell_body|FMA:67301|FBbt:00005107 cell soma The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections. GO:0010913 regulation of sterigmatocystin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010913 Any process that modulates the rate, frequency, or extent of sterigmatocystin biosynthesis. Sterigmatocystin biosynthetic processes are the chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds. CHEBI:1113 cis-2-hydroxypenta-2,4-dienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_1113 OBO:GOCHE_75763 substance with eukaryotic metabolite role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_75763 GO:0009920 cell plate formation involved in plant-type cell wall biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009920 cell plate formation involved in cellulose and pectin-containing cell wall biogenesis The cell cycle process in which the cell plate is formed at the equator of the spindle in the dividing cells during early telophase. An example of this is found in Arabidopsis thaliana. UBERON:0004756 dermal skeletal element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004756 dermal element dermis-derived entity that is made of skeletal tissue. GO:0009921 auxin efflux carrier complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009921 The protein complex associated with the plasma membrane of certain plant cells (e.g. root cortex, epidermal cells) that functions to transport auxin out of the cell. GO:0009922 fatty acid elongase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009922 MetaCyc:ICOSANOYL-COA-SYNTHASE-RXN|Reactome:R-HSA-548830|Reactome:R-HSA-2046095|Reactome:R-HSA-2046088|Reactome:R-HSA-2046083|Reactome:R-HSA-2046090|Reactome:R-HSA-548814|Reactome:R-HSA-548800|Reactome:R-HSA-2046100|Reactome:R-HSA-548815|Reactome:R-HSA-2046094 Catalysis of the reaction: fatty acid (C-16 or longer) + 2-C = fatty acid (C-16 or longer + 2-C). UBERON:0004757 rectal salt gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004757 digitiform gland|rectal gland|glandula rectalis An evagination of the terminal portion of the intestine that is capable of secreting high concentrations of excess sodium chloride. GO:0009923 fatty acid elongase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009923 A tetrameric complex of four different subunits which catalyzes the elongation of fatty acids chains 2 carbon units at a time in the synthesis of very long chain fatty acids. GO:0009924 octadecanal decarbonylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009924 RHEA:30415|MetaCyc:OCTADECANAL-DECARBONYLASE-RXN|EC:4.1.99.5 octadecanal alkane-lyase activity Catalysis of the reaction: octadecanal = heptadecane + CO. UBERON:0004755 skeletal tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004755 A specialized form of connective tissue in which the extracellular matrix is firm, providing the tissue with resilience, and/or mineralized and that functions in mechanical and structural support.[VSAO] GO:0009925 basal plasma membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0009925 The region of the plasma membrane located at the basal end of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis. UBERON:0004753 scapulocoracoid biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004753 coraco-scapular cartilage|scapulocoracoideum|scapulocoracoid cartilage|scapulo-coracoid cartilage Skeletal element that consists of the scapula and the coracoid[VSAO, modified]. GO:0009926 auxin polar transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009926 The unidirectional movement of auxin in the stem from tip to base along the vector of gravity or basipetally. UBERON:0004750 blastoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004750 membrana germinativa|germinal membrane A layer of cells formed at one pole of macrolecithal eggs such as the yolky egg of birds. The yolk prevents the division from taking place through the egg, resulting in meroblastic cleavage during the many cleavage divisions. At the animal pole (containing less yolk than the vegetal pole), the zygote divides and subdivides, forming the blastoderm, which gradually spreads around the yolk and forms the embryo. The blastoderm is composed of two layers, the epiblast and the hypoblast, which enclose the fluid-filled blastocoel cavity. GO:0009927 histidine phosphotransfer kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009927 Serves as a phospho-His intermediate enabling the transfer of phospho group between a hybrid kinase and a response regulator. CHEBI:1110 2-hexaprenylphenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_1110 GO:0009928 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009928 GO:0103085 2-(5'-methylthio)pentylmalate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103085 MetaCyc:RXNQT-4169 Catalysis of the reaction: 2-oxo-7-methylthioheptanoate + acetyl-CoA + H2O <=> H+ + 2-(5'-methylthio)pentylmalate + coenzyme A. GO:0103086 methylthiopentylmalate isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103086 MetaCyc:RXNQT-4170 Catalysis of the reaction: 2-(5'-methylthio)pentylmalate <=> 3-(5'-methylthio)pentylmalate. GO:0103083 methylthiobutylmalate isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103083 MetaCyc:RXNQT-4167 Catalysis of the reaction: 2-(4'-methylthio)butylmalate <=> 3-(4'-methylthio)butylmalate. GO:0103084 methylthiobutylmalate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103084 MetaCyc:RXNQT-4168 Catalysis of the reaction: 3-(4'-methylthio)butylmalate <=> H+ + 2-oxo-7-methylthioheptanoate + carbon dioxide. GO:0103089 methylthiohexylmalate isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103089 MetaCyc:RXNQT-4173 Catalysis of the reaction: 2-(6'-methylthio)hexylmalate <=> 3-(6'-methylthio)hexylmalate. CHEBI:23511 cysteinyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23511 GO:0103087 methylthiopentylmalate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103087 MetaCyc:RXNQT-4171 Catalysis of the reaction: 3-(5'-methylthio)pentylmalate <=> H+ + 2-oxo-8-methylthiooctanoate + carbon dioxide. GO:0103088 2-(6'-methylthio)hexylmalate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103088 MetaCyc:RXNQT-4172 Catalysis of the reaction: 2-oxo-8-methylthiooctanoate + acetyl-CoA + H2O <=> H+ + 2-(6'-methylthio)hexylmalate + coenzyme A. CHEBI:23518 cytidine 3'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23518 GO:0103092 methylthioalkylmalate isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103092 MetaCyc:RXNQT-4176 Catalysis of the reaction: 2-(7'-methylthio)heptylmalate <=> 3-(7'-methylthio)heptylmalate. GO:0103093 methylthioalkylmalate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103093 MetaCyc:RXNQT-4178 Catalysis of the reaction: 3-(7'-methylthio)heptylmalate <=> H+ + 2-oxo-10-methylthiodecanoate + carbon dioxide. GO:0103090 methylthiohexylmalate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103090 MetaCyc:RXNQT-4174 Catalysis of the reaction: 3-(6'-methylthio)hexylmalate <=> H+ + 2-oxo-9-methylthiononanoate + carbon dioxide. GO:0103091 2-(7'-methylthio)heptylmalate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103091 MetaCyc:RXNQT-4175 Catalysis of the reaction: 2-oxo-9-methylthiononanoate + acetyl-CoA + H2O <=> H+ + 2-(7'-methylthio)heptylmalate + coenzyme A. GO:0103096 CYP79F1 dihomomethionine monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103096 MetaCyc:RXNQT-4309|RHEA:32719 Catalysis of the reaction: dihomomethionine + 2 O2 + 2 NADPH + 2 H+ <=> 5-methylthiopentanaldoxime + 3 H2O + carbon dioxide + 2 NADP. GO:0009907 response to photoperiod, red light biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009907 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light photoperiod stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. GO:0103097 CYP79F1 trihomomethionine monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103097 MetaCyc:RXNQT-4310|RHEA:32723 Catalysis of the reaction: trihomomethionine + 2 O2 + 2 NADPH + 2 H+ <=> 3 H2O + carbon dioxide + 2 NADP + 6-methylthiohexanaldoxime. GO:0009908 flower development biolink:BiologicalProcess go-plus goslim_plant http://purl.obolibrary.org/obo/GO_0009908 The process whose specific outcome is the progression of the flower over time, from its formation to the mature structure. The flower is the reproductive structure in a plant, and its development begins with the transition of the vegetative or inflorescence meristem into a floral meristem. CHEBI:23521 cytidine 5'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23521 GO:0009909 regulation of flower development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009909 Any process that modulates the frequency, rate or extent of flower development. GO:0103095 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0103095 CHEBI:23524 cytidines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23524 GO:0103098 CYP79F1 tetrahomomethionine monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103098 MetaCyc:RXNQT-4311 Catalysis of the reaction: 2 H+ + tetrahomomethionine + 2 O2 + 2 NADPH <=> 3 H2O + carbon dioxide + 2 NADP + 7-methylthioheptanaldoxime. GO:0103099 UDP-glucose:5-methylthiopentylhydroximate S-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0103099 EC:2.4.1.195|MetaCyc:RXNQT-4324 Catalysis of the reaction: UDP-alpha-D-glucose + 5-methylthiopentylhydroximate <=> H+ + 4-methylthiobutyldesulfoglucosinolate + UDP. CHEBI:23523 cytidine phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23523 CHEBI:1178 (2S)-2-isopropylmalate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_1178 CHEBI:23528 cytochalasin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23528 GO:0009900 dehiscence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009900 Wikipedia:Dehiscence_(botany) The opening of an anther, fruit or other structure, which permits the escape of reproductive bodies contained within it. GO:0009901 anther dehiscence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009901 The dehiscence of an anther to release the pollen grains contained within it. CHEBI:1171 2-hydroxypropylphosphonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_1171 GO:0009902 chloroplast relocation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009902 chloroplast movement The process in which chloroplasts in photosynthetic cells migrate toward illuminated sites to optimize photosynthesis and move away from excessively illuminated areas to protect the photosynthetic machinery. CHEBI:23527 cytochalasin B biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_23527 GO:0009903 chloroplast avoidance movement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009903 high-fluence-rate response The relocation process in which chloroplasts in photosynthetic cells avoid strong light and move away from it in order to preserve the photosynthetic machinery. GO:0009904 chloroplast accumulation movement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009904 low-fluence-rate response The relocation process in which chloroplasts in photosynthetic cells move toward a brighter area in a cell to optimize photosynthesis. GO:0009905 ent-copalyl diphosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009905 EC:5.5.1.13|KEGG_REACTION:R02068|RHEA:14841|MetaCyc:5.5.1.13-RXN ent-kaurene synthetase A activity|ent-copalyl-diphosphate lyase (decyclizing)|ent-kaurene synthase A activity|diterpene cyclase activity Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = ent-copalyl diphosphate. GO:0009906 response to photoperiod, blue light biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009906 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a blue light photoperiod stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm. CHEBI:1148 2-hydroxybutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_1148 CHEBI:23503 4-amino-1,2-oxazolidin-3-one biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23503 CHEBI:23500 cyclopropanecarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23500 UBERON:0004792 secretion of endocrine pancreas biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004792 endocrine pancreas secretion|pars endocrina pancreatis secretion|pancreatic endocrine secretion|secretion of pars endocrina pancreatis A secretion that is part of a endocrine pancreas [Automatically generated definition]. UBERON:0004793 secretion of exocrine pancreas biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004793 pancreatic exocrine secretion|secretion of pars exocrina pancreatis|pars exocrina pancreatis secretion|exocrine pancreas secretion A secretion that is part of a exocrine pancreas [Automatically generated definition]. CHEBI:1156 2-hydroxyestrone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_1156 UBERON:0004790 skin mucous gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004790 mucous gland of entire skin|skin of body mucous gland|mucous gland of skin of body|skin mucus gland A mucous gland that is part of the skin. CHEBI:1157 isethionic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_1157 UBERON:0004791 thymus trabecula biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004791 thymus gland trabecula|trabecula of thymus|thymic trabecula|trabecula of thymus gland the thymic connective tissue which extends into the parenchyma CHEBI:1159 2-hydroxyethylphosphonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_1159 CHEBI:23505 cystathionines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23505 UBERON:0004796 prostate gland secretion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004796 prostate fluid|secretion of prostate|prostatic fluid|prostate secretion|secretion of prostate gland A bodily secretion that is produced by the prostate gland. UBERON:0004797 blood vessel layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004797 Any of the tissue layers that comprise a blood vessel. Examples: tunica media, tunica adventitia. UBERON:0004794 esophagus secretion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004794 oesophagus secretion|secretion of gullet|secretion of esophagus|gullet secretion|secretion of oesophagus|esophageal secretion A secretion that is part of a esophagus [Automatically generated definition]. CHEBI:23509 cysteine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_23509 UBERON:0004795 pancreas secretion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0004795 pancreatic secretion|secretion of pancreas A secretion that is part of a pancreas [Automatically generated definition]. UBERON:0011591 tract of diencephalon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011591 diencephalon tract An axon tract that is part of a diencephalon. UBERON:0011590 commissure of diencephalon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011590 diencephalon commissure A commissure that is part of a diencephalon. UBERON:0011595 jaw region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011595 A subdivision of the head that corresponds to the jaw skeleton, containing both soft tissue, skeleton and teeth (when present). The jaw region is divided into upper and lower regions. UBERON:0011594 dentary tooth biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011594 tooth of dentary|mandibular teeth|mandibular tooth Tooth that is attached to a dentary/mandible[TAO,modified]. UBERON:0011593 maxillary tooth biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011593 maxillary teeth A tooth that is attached to a maxilla[TAO,modified]. UBERON:0011592 future upper lip biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011592 upper jaw future lip UBERON:0011597 bone of upper jaw biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011597 upper jaw bone Any bone that is part of the upper jaw skeleton. This includes (when present): the maxilla, the quadrate (in some species). UBERON:0011596 future lower lip biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011596 lower jaw future lip UBERON:0011589 non-mineralized cartilage tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011589 Cartilage tissue that is not mineralized. CHEBI:38522 pyrrolizines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38522 CHEBI:38526 quinolizidine alkaloid fundamental parent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38526 CHEBI:38521 pyrrolizine alkaloid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38521 UBERON:0035570 tectothalamic tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035570 tectothalamic tract|tectothalamic pathway|tectothalamic fibers|fibre tettotalamiche@it|tectothalamic fibers|ttp UBERON:0011584 zeugopodial skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011584 zygopodium|zeugopod skeleton|mesomere 2 skeleton|epipodium|mesomere 2|skeleton of zeugopod|epipodial skeleton Section of the forelimb skeleton located between the stylopodium and the autopodium. UBERON:0011583 stylopodial skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011583 stylopodium skeleton|stylopodium|proximal metapterygial mesomere|propodial skeleton|mesomere 1|stylopod|propodium Proximal element of a free limb skeleton consisting of the femur and humerus in the forelimb stylopodium and hindlimb stylopodium respectively[VSAO, modified]. UBERON:0011582 paired limb/fin skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011582 skeletal parts of limb/fin|skeleton of limb/fin|limb/fin skeleton The collection of all skeletal elements in an individual limb or fin. UBERON:0011588 pre-enamel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011588 pre-enamel tissue|preenamel tissue Odontogenic tissue that is avascular non-mineralized matrix that is deposited by preameloblast and ameloblasts that are excluded from the matrix. UBERON:0011587 pre-dentine biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011587 pre-dentine tissue|predentine tissue|predentin Odontogenic tissue that is collagen-rich and characteristic of vertebrate teeth and tooth-like structures (e.g., odontodes) deposited by preodontoblasts and odontoblasts that are typically excluded from the matrix. UBERON:0011585 cell condensation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011585 Anatomical structure that is an aggregation of similar cells from which cartilages and bones form, and from which chondrogenesis and osteogenesis are initiated during repair and/or regeneration. (Hall and Miyake 1995). CHEBI:38532 hydrazone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38532 CHEBI:38530 quinazolines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38530 CHEBI:63510 EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63510 UBERON:0011574 mesonephric duct lumen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011574 cavity of nephric duct|nephric duct lumen A tube lumen that is part of a mesonephric duct. CHEBI:38503 EC 1.6.5.3 [NADH:ubiquinone reductase (H(+)-translocating)] inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38503 CHEBI:38500 EC 1.9.3.1 (cytochrome c oxidase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38500 UBERON:0035597 profundal placode biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035597 ophthalmic lobe of trigeminal placode complex|profundus placode|ophthalmic lobe of trigeminal placode|ophthalmic placode An embryonic structure positioned halfway between the prospective eye and ear, adjacent to the future midbrain-hindbrain boundary. The profundal and the trigeminal ganglia are separate distally but fused at their proximal end as they condense around NF stage 24. UBERON:0011566 lumen of esophagus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011566 cavity of eosophagus|esophageal lumen|cavity of esophagus|eosophageal lumen|eosophagus lumen|eosophageal cavity|esophagus lumen|esophageal cavity An anatomical cavity that is part of a esophagus. UBERON:0011565 lumen of gastrointestinal system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011565 gastrointestinal tract lumen|cavity of gastrointestinal tract|cavity of digestive tract|lumen of gastrointestinal tract CHEBI:63525 D-mannosyl-D-glycerate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63525 CHEBI:63524 5-hydroxyectoinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63524 CHEBI:63523 fructosyllysinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63523 CHEBI:38512 dibenzoquinolizine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38512 CHEBI:38518 benzophenanthridine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38518 CHEBI:63529 guanyl deoxyribonucleotide oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63529 CHEBI:38517 benzophenanthridine alkaloid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38517 CHEBI:63528 dTMP(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63528 CHEBI:63527 TTP(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63527 CHEBI:38515 isoquinoline alkaloid fundamental parent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38515 CHEBI:63526 platinum cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63526 UBERON:0035523 anterior surface of prostate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035523 anterior surface of prostate gland|facies anterior (prostatae)|facies anterior prostatae The aspect of the prostate facing the pubic symphysis. CHEBI:63534 monoamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63534 CHEBI:87504 (2Z,4Z)-2-hydroxyhepta-2,4-dienedioate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87504 CHEBI:87507 (4Z)-2-oxohept-4-enedioate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87507 CHEBI:63539 (5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63539 CHEBI:87509 (2R,3E)-5-oxopent-3-ene-1,2,5-tricarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87509 CHEBI:63543 (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63543 CHEBI:63542 (8Z,11Z,14Z,17Z)-icosatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63542 CHEBI:63541 (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63541 CHEBI:63540 (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63540 CHEBI:63547 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63547 CHEBI:63546 (6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63546 CHEBI:63545 (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63545 CHEBI:63544 (7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63544 UBERON:0035529 left common iliac artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035529 trunk of left common iliac arterial tree CHEBI:63548 (9Z,12Z,15Z,18Z)-tetracosatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63548 CHEBI:63550 TTP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63550 CHEBI:63553 2-hydroxy-1-phenyl-1-propanone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63553 UBERON:0035546 uveal vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035546 ciliary vein CHEBI:63552 1-phenyl-1,2-propanedione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63552 UBERON:0035545 deep lymphatic vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035545 deep lymph vessel The tubules that carry lymph throughout the body that are in the interior of the body or limbs. CHEBI:63551 carbohydrate acid derivative anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63551 CHEBI:87522 (S)-4-hydroxy-2-oxoheptanedioate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87522 CHEBI:63558 DIBOA biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63558 UBERON:0035539 esophageal artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035539 oesophageal artery|aortic esophageal artery Any of several arteries that arise from the aorta and supply blood to the esophagus. CHEBI:63559 HBOA biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63559 UBERON:0035551 deep vasculature biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035551 deep part of circulatory system The part of the circulatory system that lies deep beneath the subcutaneous tissue layers away from the surface of the skin. CHEBI:63561 ketoaldonate derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63561 UBERON:0035550 superficial vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035550 superficial veins|superficial vessels|superfical vein Any of the veins carrying deoxygenated blood from the subcutaneous tissue layers. UBERON:0035553 left cardiac chamber biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035553 Any chamber of the left side of the heart UBERON:0035552 deep vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035552 deep veins|deep vessels A blood vessel carrying deoxygenated blood far beneath the skin usually accompanying an artery. UBERON:0035555 lateral line sense organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035555 UBERON:0035554 right cardiac chamber biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035554 Any chamber of the right side of the heart CHEBI:63563 oligosaccharide derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63563 UBERON:0035548 colic artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035548 CHEBI:63567 tetrasaccharide derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63567 UBERON:0035549 vasculature of integument biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035549 vasculature of skin|hypodermis vasculature|skin vasculature|subcutaneous vasculature|superficial vasculature|dermis vasculature|superficial part of circulatory system The part of the circulatory system that lies within the subcutaneous tissue layers close to the surface of the skin. CHEBI:63566 pentasaccharide derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63566 CHEBI:87518 ADP(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87518 GO:1903349 omegasome membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1903349 Any membrane that is part of an omegasome. GO:1903348 positive regulation of bicellular tight junction assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903348 up-regulation of tight junction formation|activation of tight junction formation|up-regulation of tight junction assembly|upregulation of tight junction assembly|positive regulation of tight junction formation|up regulation of tight junction formation|up regulation of tight junction assembly|activation of tight junction assembly|upregulation of tight junction formation Any process that activates or increases the frequency, rate or extent of tight junction assembly. GO:1903347 negative regulation of bicellular tight junction assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903347 down-regulation of tight junction assembly|inhibition of tight junction assembly|down-regulation of tight junction formation|negative regulation of tight junction formation|down regulation of tight junction assembly|downregulation of tight junction formation|downregulation of tight junction assembly|down regulation of tight junction formation|inhibition of tight junction formation Any process that stops, prevents or reduces the frequency, rate or extent of tight junction assembly. GO:1903346 positive regulation of protein polyglycylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903346 up regulation of protein polyglycylation|activation of protein polyglycylation|up-regulation of protein polyglycylation|upregulation of protein polyglycylation Any process that activates or increases the frequency, rate or extent of protein polyglycylation. GO:1903345 negative regulation of protein polyglycylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903345 down-regulation of protein polyglycylation|inhibition of protein polyglycylation|down regulation of protein polyglycylation|downregulation of protein polyglycylation Any process that stops, prevents or reduces the frequency, rate or extent of protein polyglycylation. UBERON:0011510 cloacal bursa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011510 An evagination of the cloaca. In Testudines these are hypothesized to function in different physiological roles, primarily in respiration. CHEBI:133618 leukotriene F4(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133618 GO:1903344 regulation of protein polyglycylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903344 Any process that modulates the frequency, rate or extent of protein polyglycylation. GO:1903343 positive regulation of meiotic DNA double-strand break formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903343 upregulation of meiotic DNA double-strand break formation|up regulation of meiotic DNA double-strand break formation|activation of meiotic DNA double-strand break formation|up-regulation of meiotic DNA double-strand break formation Any process that activates or increases the frequency, rate or extent of meiotic DNA double-strand break formation. GO:1903353 regulation of nucleus organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903353 regulation of nucleus organization and biogenesis|regulation of nuclear organisation|regulation of nuclear morphology|regulation of nuclear organization and biogenesis|regulation of nuclear organization Any process that modulates the frequency, rate or extent of nucleus organization. GO:1903352 L-ornithine transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903352 The directed movement of L-ornithine across a membrane. GO:1903351 cellular response to dopamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903351 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus. GO:1903350 response to dopamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903350 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus. CHEBI:7101 N(5)-[(Z)-amino(hydroxyimino)methyl]ornithine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_7101 GO:1903359 lateral cortical node assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903359 lateral cortical node formation|Skb1-containing cortical node formation|Skb1-containing cortical node assembly The aggregation, arrangement and bonding together of a set of components to form a lateral cortical node. GO:1903358 regulation of Golgi organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903358 regulation of Golgi organisation|regulation of Golgi organization and biogenesis Any process that modulates the frequency, rate or extent of Golgi organization. GO:1903357 regulation of transcription initiation from RNA polymerase I promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903357 regulation of transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript Any process that modulates the frequency, rate or extent of transcription initiation from RNA polymerase I promoter. GO:1903356 positive regulation of distal tip cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903356 up-regulation of distal tip cell migration|upregulation of distal tip cell migration|up regulation of distal tip cell migration|activation of distal tip cell migration Any process that activates or increases the frequency, rate or extent of distal tip cell migration. GO:1903355 negative regulation of distal tip cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903355 inhibition of distal tip cell migration|down regulation of distal tip cell migration|downregulation of distal tip cell migration|down-regulation of distal tip cell migration Any process that stops, prevents or reduces the frequency, rate or extent of distal tip cell migration. GO:1903354 regulation of distal tip cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903354 Any process that modulates the frequency, rate or extent of distal tip cell migration. GO:1903364 positive regulation of cellular protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903364 positive regulation of cellular protein degradation|up regulation of cellular protein degradation|up regulation of cellular protein catabolism|activation of cellular protein catabolism|positive regulation of cyclin catabolism|positive regulation of cellular protein breakdown|positive regulation of cellular protein catabolism|up regulation of cellular protein breakdown|up regulation of cellular protein catabolic process|upregulation of cellular protein degradation|up-regulation of cellular protein catabolism|positive regulation of cyclin degradation|upregulation of cellular protein breakdown|up-regulation of cellular protein degradation|upregulation of cellular protein catabolic process|activation of cellular protein degradation|positive regulation of cyclin breakdown|upregulation of cellular protein catabolism|activation of cellular protein breakdown|up-regulation of cellular protein breakdown|positive regulation of degradation of cyclin|positive regulation of cyclin catabolic process|activation of cellular protein catabolic process|up-regulation of cellular protein catabolic process Any process that activates or increases the frequency, rate or extent of cellular protein catabolic process. GO:1903363 negative regulation of cellular protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903363 downregulation of cellular protein catabolism|negative regulation of degradation of cyclin|negative regulation of cellular protein breakdown|down-regulation of cellular protein breakdown|downregulation of cellular protein degradation|down-regulation of cellular protein catabolic process|negative regulation of cyclin catabolism|down-regulation of cellular protein catabolism|negative regulation of cellular protein catabolism|down regulation of cellular protein degradation|downregulation of cellular protein breakdown|inhibition of cellular protein degradation|down regulation of cellular protein breakdown|downregulation of cellular protein catabolic process|negative regulation of cyclin degradation|inhibition of cellular protein catabolism|inhibition of cellular protein breakdown|down regulation of cellular protein catabolic process|negative regulation of cyclin breakdown|inhibition of cellular protein catabolic process|negative regulation of cyclin catabolic process|down regulation of cellular protein catabolism|down-regulation of cellular protein degradation|negative regulation of cellular protein degradation Any process that stops, prevents or reduces the frequency, rate or extent of cellular protein catabolic process. GO:1903362 regulation of cellular protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903362 regulation of cyclin catabolic process|regulation of cellular protein degradation|regulation of cellular protein breakdown|regulation of degradation of cyclin|regulation of cyclin degradation|regulation of cyclin breakdown|regulation of cellular protein catabolism|regulation of cyclin catabolism Any process that modulates the frequency, rate or extent of cellular protein catabolic process. GO:1903361 protein localization to basolateral plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903361 protein localisation to basolateral plasma membrane|basolateral protein localization|protein localization in basolateral plasma membrane|protein localisation in basolateral plasma membrane Any process in which a protein is transported to, or maintained in, basolateral regions of the plasma membrane. GO:1903360 protein localization to lateral cortical node biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903360 protein localisation to lateral cortical node|protein localization in lateral cortical node|protein localisation in lateral cortical node A process in which a protein is transported to, or maintained in, a location within a lateral cortical node. GO:1903369 negative regulation of foraging behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903369 down regulation of foraging behavior|downregulation of foraging behavior|down-regulation of foraging behavior|inhibition of foraging behavior Any process that stops, prevents or reduces the frequency, rate or extent of foraging behavior. GO:1903368 regulation of foraging behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903368 Any process that modulates the frequency, rate or extent of foraging behavior. GO:1903367 positive regulation of fear response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903367 up-regulation of fear response|up regulation of physiological fear response|activation of physiological fear response|positive regulation of physiological fear response|upregulation of fear response|up-regulation of physiological fear response|up regulation of fear response|activation of fear response|upregulation of physiological fear response Any process that activates or increases the frequency, rate or extent of fear response. GO:1903366 negative regulation of fear response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903366 downregulation of physiological fear response|inhibition of fear response|negative regulation of physiological fear response|down-regulation of physiological fear response|down regulation of fear response|inhibition of physiological fear response|downregulation of fear response|down-regulation of fear response|down regulation of physiological fear response Any process that stops, prevents or reduces the frequency, rate or extent of fear response. GO:1903365 regulation of fear response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903365 regulation of physiological fear response Any process that modulates the frequency, rate or extent of fear response. GO:1903375 facioacoustic ganglion development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903375 facio-acoustic VII-VIII ganglion complex development|acousticofacial ganglion development|acoustico-facial VII-VIII ganglion complex development|facio-acoustic ganglion development|facio-acoustic ganglion complex VII-VIII development The process whose specific outcome is the progression of an acoustico-facial VII-VIII ganglion complex over time, from its formation to the mature structure. GO:1903374 subarachnoid space development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903374 subarachnoid cavity development|spatium subarachnoideum development|cavitas subarachnoidea development|cavum subarachnoideale development|spatium leptomeningeum development The process whose specific outcome is the progression of a subarachnoid space over time, from its formation to the mature structure. GO:1903373 positive regulation of endoplasmic reticulum tubular network organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903373 upregulation of endoplasmic reticulum tubular network organization|up-regulation of endoplasmic reticulum tubular network organisation|activation of endoplasmic reticulum tubular network organisation|up regulation of ER tubular network organization|positive regulation of ER tubular network organization|activation of ER tubular network organization|up-regulation of endoplasmic reticulum tubular network organization|activation of endoplasmic reticulum tubular network organization|up-regulation of ER tubular network organisation|positive regulation of endoplasmic reticulum tubular network organisation|up regulation of endoplasmic reticulum tubular network organisation|up-regulation of ER tubular network organization|upregulation of ER tubular network organisation|up regulation of endoplasmic reticulum tubular network organization|upregulation of endoplasmic reticulum tubular network organisation|upregulation of ER tubular network organization|up regulation of ER tubular network organisation|activation of ER tubular network organisation|positive regulation of ER tubular network organisation Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum tubular network organization. GO:1903372 negative regulation of endoplasmic reticulum tubular network organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903372 downregulation of ER tubular network organization|down-regulation of ER tubular network organisation|negative regulation of ER tubular network organisation|down-regulation of endoplasmic reticulum tubular network organisation|negative regulation of endoplasmic reticulum tubular network organisation|negative regulation of ER tubular network organization|inhibition of ER tubular network organisation|down-regulation of ER tubular network organization|down-regulation of endoplasmic reticulum tubular network organization|inhibition of ER tubular network organization|downregulation of endoplasmic reticulum tubular network organisation|down regulation of ER tubular network organisation|down regulation of endoplasmic reticulum tubular network organisation|inhibition of endoplasmic reticulum tubular network organisation|downregulation of endoplasmic reticulum tubular network organization|downregulation of ER tubular network organisation|down regulation of endoplasmic reticulum tubular network organization|down regulation of ER tubular network organization|inhibition of endoplasmic reticulum tubular network organization Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum tubular network organization. GO:1903371 regulation of endoplasmic reticulum tubular network organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903371 regulation of endoplasmic reticulum tubular network organisation|regulation of ER tubular network organisation|regulation of ER tubular network organization Any process that modulates the frequency, rate or extent of endoplasmic reticulum tubular network organization. GO:1903370 positive regulation of foraging behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903370 up-regulation of foraging behavior|upregulation of foraging behavior|up regulation of foraging behavior|activation of foraging behavior Any process that activates or increases the frequency, rate or extent of foraging behavior. CHEBI:38582 difluorobenzene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38582 CHEBI:38584 1,3-difluorobenzene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38584 CHEBI:133603 methanesulfinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133603 CHEBI:133606 1-octadecanoyl-2-arachidonoyl-sn-glycero-3-phospho-D-myo-inositol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133606 GO:1903379 regulation of mitotic chromosome condensation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903379 Any process that modulates the frequency, rate or extent of mitotic chromosome condensation. GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903378 positive regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|up-regulation of neuron apoptosis in response to oxidative stress|activation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|up-regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|activation of neuron apoptosis in response to oxidative stress|positive regulation of neuron apoptosis in response to oxidative stress|up regulation of neuron apoptosis in response to oxidative stress|up regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|upregulation of neuron apoptosis in response to oxidative stress|upregulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress Any process that activates or increases the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway. GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903377 negative regulation of oxidative stress-induced neuron apoptosis|negative regulation of neuron apoptosis in response to oxidative stress|down-regulation of neuron apoptosis in response to oxidative stress|down-regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|protection against oxidative stress-induced neuronal apoptosis|downregulation of neuron apoptosis in response to oxidative stress|downregulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|neuroprotection against oxidative stress-induced apoptosis|protection against oxidative stress-induced neuron apoptosis|down regulation of neuron apoptosis in response to oxidative stress|down regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|inhibition of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|negative regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|inhibition of neuron apoptosis in response to oxidative stress Any process that stops, prevents or reduces the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway. GO:1903376 regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903376 regulation of oxidative stress-induced neuron apoptosis|regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|regulation of neuron apoptosis in response to oxidative stress|regulation of oxidative stress-induced neuronal apoptosis Any process that modulates the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway. GO:1903386 negative regulation of homophilic cell adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903386 downregulation of homophilic cell adhesion|down regulation of homophilic cell adhesion|inhibition of homophilic cell adhesion|down-regulation of homophilic cell adhesion Any process that stops, prevents or reduces the frequency, rate or extent of homophilic cell adhesion. GO:1903385 regulation of homophilic cell adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903385 Any process that modulates the frequency, rate or extent of homophilic cell adhesion. GO:1903384 negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903384 down regulation of neuron apoptosis in response to hydrogen peroxide|down-regulation of neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide|downregulation of neuron apoptosis in response to hydrogen peroxide|down regulation of H2O2-induced neuron intrinsic apoptotic signaling pathway|downregulation of neuron intrinsic apoptotic signaling pathway in response to H2O2|protection against hydrogen peroxide-induced neuron apoptosis|inhibition of neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide|downregulation of H2O2-induced neuron intrinsic apoptotic signaling pathway|down regulation of neuron intrinsic apoptotic signaling pathway in response to H2O2|inhibition of neuron intrinsic apoptotic signaling pathway in response to H2O2|negative regulation of neuron apoptosis in response to hydrogen peroxide|down-regulation of neuron apoptosis in response to hydrogen peroxide|negative regulation of neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide|down-regulation of H2O2-induced neuron intrinsic apoptotic signaling pathway|negative regulation of H2O2-induced neuron intrinsic apoptotic signaling pathway|down regulation of neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide|inhibition of neuron apoptosis in response to hydrogen peroxide|downregulation of neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide|inhibition of H2O2-induced neuron intrinsic apoptotic signaling pathway|protection against H2O2-induced neuron apoptosis|down-regulation of neuron intrinsic apoptotic signaling pathway in response to H2O2|negative regulation of neuron intrinsic apoptotic signaling pathway in response to H2O2 Any process that stops, prevents or reduces the frequency, rate or extent of a hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway. GO:1903383 regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903383 regulation of hydrogen peroxide-induced neuron apoptosis|regulation of neuron apoptosis in response to hydrogen peroxide|regulation of neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide|regulation of H2O2-induced neuron intrinsic apoptotic signaling pathway|regulation of neuron intrinsic apoptotic signaling pathway in response to H2O2|regulation of H2O2-induced neuron apoptosis|regulation of hydrogen peroxide-induced neuronal apoptosis Any process that modulates the frequency, rate or extent of a hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway. CHEBI:38599 4H-pyrazole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38599 GO:1903382 negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903382 inhibition of ER stress-induced neuron intrinsic apoptotic signaling pathway|downregulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway|down-regulation of neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|down-regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway|downregulation of neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|negative regulation of ER stress-induced neuron intrinsic apoptotic signaling pathway|down-regulation of ER stress-induced neuron intrinsic apoptotic signaling pathway|inhibition of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway|down regulation of neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|inhibition of neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|negative regulation of neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|downregulation of ER stress-induced neuron intrinsic apoptotic signaling pathway|down regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway|down regulation of ER stress-induced neuron intrinsic apoptotic signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of an endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway. GO:1903381 regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903381 regulation of neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|regulation of ER stress-induced neuron apoptosis|regulation of endoplasmic reticulum stress-induced neuron apoptosis|regulation of ER stress-induced neuron intrinsic apoptotic signaling pathway Any process that modulates the frequency, rate or extent of an endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway. GO:1903380 positive regulation of mitotic chromosome condensation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903380 up-regulation of mitotic chromosome condensation|upregulation of mitotic chromosome condensation|up regulation of mitotic chromosome condensation|activation of mitotic chromosome condensation Any process that activates or increases the frequency, rate or extent of mitotic chromosome condensation. CHEBI:38597 triazole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38597 CHEBI:38596 pyrazolide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38596 CHEBI:38595 3H-pyrazole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38595 GO:1903389 negative regulation of synaptic vesicle uncoating biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903389 down regulation of synaptic vesicle uncoating|inhibition of synaptic vesicle uncoating|negative regulation of synaptic vesicle coat depolymerization|down-regulation of synaptic vesicle coat depolymerization|negative regulation of synaptic vesicle coat protein depolymerization|down-regulation of synaptic vesicle coat protein depolymerization|downregulation of synaptic vesicle coat depolymerization|downregulation of synaptic vesicle coat protein depolymerization|down regulation of synaptic vesicle coat depolymerization|down-regulation of synaptic vesicle uncoating|inhibition of synaptic vesicle coat depolymerization|down regulation of synaptic vesicle coat protein depolymerization|inhibition of synaptic vesicle coat protein depolymerization|downregulation of synaptic vesicle uncoating Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle uncoating. GO:1903388 regulation of synaptic vesicle uncoating biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903388 regulation of synaptic vesicle coat depolymerization|regulation of synaptic vesicle coat protein depolymerization Any process that modulates the frequency, rate or extent of synaptic vesicle uncoating. GO:1903387 positive regulation of homophilic cell adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903387 up regulation of homophilic cell adhesion|upregulation of homophilic cell adhesion|up-regulation of homophilic cell adhesion|activation of homophilic cell adhesion Any process that activates or increases the frequency, rate or extent of homophilic cell adhesion. GO:1903397 positive regulation of secondary cell septum biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903397 up regulation of secondary cell septum biogenesis|upregulation of secondary cell septum biogenesis|up-regulation of secondary cell septum biogenesis|activation of secondary cell septum biogenesis Any process that activates or increases the frequency, rate or extent of secondary cell septum biogenesis. GO:1903396 negative regulation of secondary cell septum biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903396 downregulation of secondary cell septum biogenesis|down regulation of secondary cell septum biogenesis|inhibition of secondary cell septum biogenesis|down-regulation of secondary cell septum biogenesis Any process that stops, prevents or reduces the frequency, rate or extent of secondary cell septum biogenesis. GO:1903395 regulation of secondary cell septum biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903395 Any process that modulates the frequency, rate or extent of secondary cell septum biogenesis. GO:1903394 protein localization to kinetochore involved in kinetochore assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903394 condensin localization to kinetochore involved in kinetochore formation|condensin localization to kinetochore involved in centromere and kinetochore complex maturation|protein localisation to kinetochore involved in kinetochore assembly|protein localization to kinetochore involved in centromere/kinetochore complex maturation|condensin localization to kinetochore involved in chromosome-kinetochore attachment|protein localization to kinetochore involved in kinetochore formation|protein localization to kinetochore involved in centromere and kinetochore complex maturation|protein localisation to kinetochore involved in centromere/kinetochore complex maturation|condensin localization to kinetochore involved in kinetochore assembly|protein localisation to kinetochore involved in centromere and kinetochore complex maturation|protein localisation to kinetochore involved in kinetochore formation|protein localization to kinetochore involved in chromosome-kinetochore attachment|condensin localization to kinetochore involved in centromere/kinetochore complex maturation|protein localisation to kinetochore involved in chromosome-kinetochore attachment Any protein localization to kinetochore that is involved in kinetochore assembly. GO:1903393 positive regulation of adherens junction organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903393 positive regulation of adherens junction organisation|up regulation of adherens junction organisation|up regulation of adherens junction organization|positive regulation of adherens junction assembly and maintenance|up regulation of adherens junction assembly and maintenance|upregulation of adherens junction organisation|upregulation of adherens junction organization|up-regulation of adherens junction organisation|activation of adherens junction organisation|upregulation of adherens junction assembly and maintenance|up-regulation of adherens junction organization|activation of adherens junction organization|up-regulation of adherens junction assembly and maintenance|activation of adherens junction assembly and maintenance Any process that activates or increases the frequency, rate or extent of adherens junction organization. GO:1903392 negative regulation of adherens junction organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903392 down-regulation of adherens junction organization|downregulation of adherens junction organisation|negative regulation of adherens junction assembly and maintenance|down-regulation of adherens junction assembly and maintenance|down regulation of adherens junction organisation|inhibition of adherens junction organisation|downregulation of adherens junction organization|downregulation of adherens junction assembly and maintenance|down regulation of adherens junction organization|inhibition of adherens junction organization|down regulation of adherens junction assembly and maintenance|inhibition of adherens junction assembly and maintenance|negative regulation of adherens junction organisation|down-regulation of adherens junction organisation Any process that stops, prevents or reduces the frequency, rate or extent of adherens junction organization. CHEBI:14597 methylarsonite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_14597 GO:1903391 regulation of adherens junction organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903391 regulation of adherens junction organisation|regulation of adherens junction assembly and maintenance Any process that modulates the frequency, rate or extent of adherens junction organization. GO:1903390 positive regulation of synaptic vesicle uncoating biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903390 upregulation of synaptic vesicle coat depolymerization|upregulation of synaptic vesicle coat protein depolymerization|up regulation of synaptic vesicle uncoating|up-regulation of synaptic vesicle coat depolymerization|activation of synaptic vesicle coat depolymerization|up-regulation of synaptic vesicle coat protein depolymerization|activation of synaptic vesicle coat protein depolymerization|upregulation of synaptic vesicle uncoating|positive regulation of synaptic vesicle coat depolymerization|up regulation of synaptic vesicle coat depolymerization|up-regulation of synaptic vesicle uncoating|positive regulation of synaptic vesicle coat protein depolymerization|activation of synaptic vesicle uncoating|up regulation of synaptic vesicle coat protein depolymerization Any process that activates or increases the frequency, rate or extent of synaptic vesicle uncoating. CHEBI:38560 simple protein biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38560 GO:1903399 positive regulation of m7G(5')pppN diphosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903399 upregulation of decapase activity|up regulation of M(7)G(5')pppN pyrophosphatase activity|positive regulation of m7G(5')pppN pyrophosphatase activity|up regulation of m7G(5')pppN pyrophosphatase activity|up regulation of m7G(5')pppN diphosphatase activity|upregulation of 7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase activity|up regulation of decapase activity|upregulation of M(7)G(5')pppN pyrophosphatase activity|positive regulation of decapase activity|upregulation of m7G(5')pppN pyrophosphatase activity|upregulation of m7G(5')pppN diphosphatase activity|up-regulation of 7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase activity|activation of 7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase activity|activation of decapase activity|up-regulation of M(7)G(5')pppN pyrophosphatase activity|activation of M(7)G(5')pppN pyrophosphatase activity|up-regulation of m7G(5')pppN pyrophosphatase activity|activation of m7G(5')pppN pyrophosphatase activity|up-regulation of m7G(5')pppN diphosphatase activity|up-regulation of decapase activity|activation of m7G(5')pppN diphosphatase activity|positive regulation of 7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase activity|up regulation of 7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase activity|positive regulation of M(7)G(5')pppN pyrophosphatase activity Any process that activates or increases the frequency, rate or extent of m7G(5')pppN diphosphatase activity. GO:1903398 regulation of m7G(5')pppN diphosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903398 regulation of 7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase activity|regulation of M(7)G(5')pppN pyrophosphatase activity|regulation of decapase activity|regulation of m7G(5')pppN pyrophosphatase activity Any process that modulates the frequency, rate or extent of m7G(5')pppN diphosphatase activity. CHEBI:38579 peptide pheromone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38579 CHEBI:38574 ferriheme biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38574 CHEBI:38573 ferroheme biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38573 CHEBI:7125 2-acetamido-2-deoxy-D-glucopyranose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_7125 CHEBI:157662 N-(omega-linoleoyloxy-ultra-long chain fatty acyl)sphingosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_157662 CHEBI:133697 4-amino-4-de(dimethylamino)anhydrotetracycline zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133697 CHEBI:133696 desmethylanhydrotetracycline zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133696 CHEBI:157669 carbocyclic fatty acyl-CoA(4-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_157669 CHEBI:157668 carbocyclic fatty acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_157668 CHEBI:157663 N-(omega-hydroxy-ultra-long chain fatty acyl)sphingosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_157663 CHEBI:87491 (2R,3E)-5-oxopent-3-ene-1,2,5-tricarboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87491 CHEBI:143018 ultra-long-chain fatty acyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_143018 CHEBI:143017 ultra-long-chain fatty acyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_143017 CHEBI:143005 ultra-long-chain fatty acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_143005 CHEBI:143004 ultra-long-chain fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_143004 CHEBI:133673 glyphosate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133673 PR:000001240 motilin receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001240 GPR38|G-protein coupled receptor 38|MTLR|MLNR|MTLR1 A growth hormone secretagogue/motilin receptor that is a translation product of the human MLNR gene or a 1:1 ortholog thereof. The preferred ligand is motilin, an intestinal peptide that stimulates contraction of gut smooth muscle. CHEBI:133674 (aminomethyl)phosphonate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133674 PR:000001245 rhodopsin biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001245 OPN2|opsin-2|RHO An animal opsin that is a translation product of the human RHO gene or a 1:1 ortholog thereof. PR:000001255 C-C chemokine receptor type 3 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001255 CC-CKR-3|Cmkbr1l2|CCR3|CMKBR3|chemokine receptor CCR3|eosinophil eotaxin receptor|CCR-3|macrophage inflammatory protein 1-alpha receptor-like 2|MIP-1 alpha RL2|CD193|CKR3|C-C CKR-3 A chemokine receptor CCR1/3/1L that is a translation product of the human CCR3 gene or a 1:1 ortholog thereof. GO:1903309 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1903309 GO:1903308 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1903308 GO:1903307 positive regulation of regulated secretory pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903307 up regulation of regulated secretory pathway|activation of regulated secretory pathway|up-regulation of regulated secretory pathway|upregulation of regulated secretory pathway Any process that activates or increases the frequency, rate or extent of regulated secretory pathway. GO:1903306 negative regulation of regulated secretory pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903306 downregulation of regulated secretory pathway|down-regulation of regulated secretory pathway|inhibition of regulated secretory pathway|down regulation of regulated secretory pathway Any process that stops, prevents or reduces the frequency, rate or extent of regulated secretory pathway. GO:1903305 regulation of regulated secretory pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903305 Any process that modulates the frequency, rate or extent of regulated secretory pathway. GO:1903304 positive regulation of pyruvate kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903304 up-regulation of pyruvate kinase activity|activation of pyruvate kinase activity|up regulation of phosphoenol transphosphorylase activity|activation of phosphoenol transphosphorylase activity|positive regulation of phosphoenol transphosphorylase activity|up-regulation of ATP:pyruvate 2-O-phosphotransferase activity|activation of ATP:pyruvate 2-O-phosphotransferase activity|up-regulation of phosphoenolpyruvate kinase activity|up regulation of pyruvate kinase activity|up-regulation of phosphoenol transphosphorylase activity|positive regulation of ATP:pyruvate 2-O-phosphotransferase activity|upregulation of phosphoenolpyruvate kinase activity|up regulation of ATP:pyruvate 2-O-phosphotransferase activity|upregulation of pyruvate kinase activity|upregulation of phosphoenol transphosphorylase activity|up regulation of phosphoenolpyruvate kinase activity|upregulation of ATP:pyruvate 2-O-phosphotransferase activity|positive regulation of phosphoenolpyruvate kinase activity|activation of phosphoenolpyruvate kinase activity Any process that activates or increases the frequency, rate or extent of pyruvate kinase activity. GO:1903303 negative regulation of pyruvate kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903303 negative regulation of phosphoenolpyruvate kinase activity|down-regulation of phosphoenolpyruvate kinase activity|down-regulation of pyruvate kinase activity|negative regulation of phosphoenol transphosphorylase activity|down-regulation of phosphoenol transphosphorylase activity|inhibition of phosphoenolpyruvate kinase activity|negative regulation of ATP:pyruvate 2-O-phosphotransferase activity|down-regulation of ATP:pyruvate 2-O-phosphotransferase activity|inhibition of phosphoenol transphosphorylase activity|downregulation of pyruvate kinase activity|down regulation of pyruvate kinase activity|down regulation of phosphoenolpyruvate kinase activity|inhibition of pyruvate kinase activity|downregulation of ATP:pyruvate 2-O-phosphotransferase activity|downregulation of phosphoenolpyruvate kinase activity|down regulation of ATP:pyruvate 2-O-phosphotransferase activity|inhibition of ATP:pyruvate 2-O-phosphotransferase activity|down regulation of phosphoenol transphosphorylase activity|downregulation of phosphoenol transphosphorylase activity Any process that stops, prevents or reduces the frequency, rate or extent of pyruvate kinase activity. GO:1903302 regulation of pyruvate kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903302 regulation of phosphoenolpyruvate kinase activity|regulation of ATP:pyruvate 2-O-phosphotransferase activity|regulation of phosphoenol transphosphorylase activity Any process that modulates the frequency, rate or extent of pyruvate kinase activity. GO:1903301 positive regulation of hexokinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903301 activation of hexokinase type II activity|upregulation of hexokinase type IV glucokinase activity|upregulation of hexokinase type III activity|upregulation of hexokinase type I activity|up regulation of glucose ATP phosphotransferase activity|activation of hexokinase D|up-regulation of hexokinase type IV (glucokinase) activity|up-regulation of hexokinase activity|upregulation of hexokinase type IV|positive regulation of glucose ATP phosphotransferase activity|activation of glucose ATP phosphotransferase activity|up-regulation of hexokinase type II activity|positive regulation of ATP:D-hexose 6-phosphotransferase activity|upregulation of hexokinase (phosphorylating)|positive regulation of hexokinase D|up regulation of ATP:D-hexose 6-phosphotransferase activity|up regulation of ATP-dependent hexokinase activity|up regulation of hexokinase D|up regulation of hexokinase type IV glucokinase activity|up-regulation of hexokinase type I activity|activation of ATP-dependent hexokinase activity|up-regulation of hexokinase type III activity|positive regulation of ATP-dependent hexokinase activity|positive regulation of hexokinase type IV glucokinase activity|activation of hexokinase type IV glucokinase activity|upregulation of hexokinase type IV (glucokinase) activity|up-regulation of hexokinase type IV|upregulation of hexokinase activity|upregulation of hexokinase type II activity|up-regulation of glucose ATP phosphotransferase activity|up-regulation of hexokinase (phosphorylating)|activation of hexokinase type III activity|activation of hexokinase (phosphorylating)|activation of hexokinase type I activity|upregulation of ATP:D-hexose 6-phosphotransferase activity|activation of hexokinase type IV|upregulation of hexokinase D|positive regulation of hexokinase type III activity|positive regulation of hexokinase type I activity|up-regulation of ATP-dependent hexokinase activity|up-regulation of hexokinase type IV glucokinase activity|up regulation of hexokinase activity|up regulation of hexokinase type III activity|up regulation of hexokinase type I activity|up regulation of hexokinase type IV (glucokinase) activity|up regulation of hexokinase type II activity|positive regulation of hexokinase type IV|upregulation of glucose ATP phosphotransferase activity|activation of hexokinase activity|positive regulation of hexokinase type IV (glucokinase) activity|positive regulation of hexokinase type II activity|positive regulation of hexokinase (phosphorylating)|up regulation of hexokinase type IV|up-regulation of ATP:D-hexose 6-phosphotransferase activity|up regulation of hexokinase (phosphorylating)|up-regulation of hexokinase D|activation of ATP:D-hexose 6-phosphotransferase activity|activation of hexokinase type IV (glucokinase) activity|upregulation of ATP-dependent hexokinase activity Any process that activates or increases the frequency, rate or extent of hexokinase activity. GO:1903300 negative regulation of hexokinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903300 down regulation of ATP-dependent hexokinase activity|down regulation of hexokinase type IV|down regulation of hexokinase type IV glucokinase activity|down-regulation of ATP:D-hexose 6-phosphotransferase activity|negative regulation of ATP:D-hexose 6-phosphotransferase activity|down regulation of hexokinase (phosphorylating)|down-regulation of hexokinase D|negative regulation of hexokinase D|inhibition of hexokinase activity|inhibition of hexokinase (phosphorylating)|downregulation of ATP-dependent hexokinase activity|inhibition of hexokinase type I activity|inhibition of hexokinase type III activity|downregulation of hexokinase type IV glucokinase activity|negative regulation of glucose ATP phosphotransferase activity|inhibition of hexokinase type IV|down-regulation of glucose ATP phosphotransferase activity|inhibition of hexokinase type IV (glucokinase) activity|inhibition of hexokinase type II activity|downregulation of ATP:D-hexose 6-phosphotransferase activity|downregulation of hexokinase D|down-regulation of ATP-dependent hexokinase activity|negative regulation of ATP-dependent hexokinase activity|negative regulation of hexokinase type IV glucokinase activity|inhibition of glucose ATP phosphotransferase activity|down regulation of ATP:D-hexose 6-phosphotransferase activity|down-regulation of hexokinase type IV glucokinase activity|down regulation of hexokinase type IV (glucokinase) activity|down regulation of hexokinase D|down regulation of hexokinase activity|negative regulation of hexokinase type I activity|down-regulation of hexokinase type I activity|negative regulation of hexokinase type III activity|inhibition of ATP:D-hexose 6-phosphotransferase activity|down-regulation of hexokinase type III activity|down regulation of hexokinase type II activity|downregulation of hexokinase type IV (glucokinase) activity|negative regulation of hexokinase type IV|downregulation of hexokinase activity|down-regulation of hexokinase type IV|downregulation of hexokinase type II activity|inhibition of ATP-dependent hexokinase activity|inhibition of hexokinase type IV glucokinase activity|down-regulation of hexokinase (phosphorylating)|negative regulation of hexokinase (phosphorylating)|inhibition of hexokinase D|downregulation of hexokinase type I activity|downregulation of hexokinase type III activity|down regulation of glucose ATP phosphotransferase activity|down-regulation of hexokinase activity|negative regulation of hexokinase type IV (glucokinase) activity|downregulation of hexokinase type IV|down-regulation of hexokinase type IV (glucokinase) activity|negative regulation of hexokinase type II activity|down regulation of hexokinase type III activity|down regulation of hexokinase type I activity|down-regulation of hexokinase type II activity|downregulation of hexokinase (phosphorylating)|downregulation of glucose ATP phosphotransferase activity Any process that stops, prevents or reduces the frequency, rate or extent of hexokinase activity. CHEBI:133653 hydroperoxy(hydroxy)icosapentaenoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133653 CHEBI:133652 hydroperoxy(epoxy)icosatrienoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133652 CHEBI:133654 hydroxydocosapentaenoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133654 CHEBI:157625 alpha-D-mannopyranuronate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_157625 GO:1903319 positive regulation of protein maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903319 upregulation of protein maturation|up-regulation of protein maturation|activation of protein maturation|up regulation of protein maturation Any process that activates or increases the frequency, rate or extent of protein maturation. GO:1903318 negative regulation of protein maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903318 down regulation of protein maturation|inhibition of protein maturation|down-regulation of protein maturation|downregulation of protein maturation Any process that stops, prevents or reduces the frequency, rate or extent of protein maturation. GO:1903317 regulation of protein maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903317 Any process that modulates the frequency, rate or extent of protein maturation. GO:1903316 positive regulation of nitrogen cycle metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903316 up-regulation of nitrogen cycle metabolic process|activation of nitrogen cycle metabolic process|up regulation of nitrogen cycle metabolic process|upregulation of nitrogen cycle metabolic process Any process that activates or increases the frequency, rate or extent of nitrogen cycle metabolic process. GO:1903315 negative regulation of nitrogen cycle metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903315 down-regulation of nitrogen cycle metabolic process|downregulation of nitrogen cycle metabolic process|down regulation of nitrogen cycle metabolic process|inhibition of nitrogen cycle metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of nitrogen cycle metabolic process. GO:1903314 regulation of nitrogen cycle metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903314 Any process that modulates the frequency, rate or extent of nitrogen cycle metabolic process. GO:1903313 positive regulation of mRNA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903313 upregulation of mRNA metabolism|up-regulation of mRNA metabolic process|activation of mRNA metabolic process|up regulation of mRNA metabolism|positive regulation of mRNA metabolism|activation of mRNA metabolism|up regulation of mRNA metabolic process|up-regulation of mRNA metabolism|upregulation of mRNA metabolic process Any process that activates or increases the frequency, rate or extent of mRNA metabolic process. CHEBI:167047 mannosyl-alpha-1->6-inositol-1-phosphodihydroceramide(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_167047 GO:1903312 negative regulation of mRNA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903312 down regulation of mRNA metabolism|downregulation of mRNA metabolism|down-regulation of mRNA metabolic process|down-regulation of mRNA metabolism|negative regulation of mRNA metabolism|downregulation of mRNA metabolic process|down regulation of mRNA metabolic process|inhibition of mRNA metabolism|inhibition of mRNA metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of mRNA metabolic process. GO:1903311 regulation of mRNA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903311 regulation of mRNA metabolism Any process that modulates the frequency, rate or extent of mRNA metabolic process. GO:1903310 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1903310 GO:1903320 regulation of protein modification by small protein conjugation or removal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903320 Any process that modulates the frequency, rate or extent of protein modification by small protein conjugation or removal. CHEBI:133661 hyocholate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133661 CHEBI:167056 polyprenol diphosphate(3-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_167056 CHEBI:167055 Jasmonate derivatives biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_167055 CHEBI:157606 sphinga-(4E,8Z)-dienine(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_157606 GO:1903329 regulation of iron-sulfur cluster assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903329 Any process that modulates the frequency, rate or extent of iron-sulfur cluster assembly. GO:1903328 positive regulation of tRNA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903328 up-regulation of tRNA metabolism|up regulation of tRNA metabolic process|upregulation of tRNA metabolism|upregulation of tRNA metabolic process|up regulation of tRNA metabolism|activation of tRNA metabolism|positive regulation of tRNA metabolism|up-regulation of tRNA metabolic process|activation of tRNA metabolic process Any process that activates or increases the frequency, rate or extent of tRNA metabolic process. GO:1903327 negative regulation of tRNA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903327 inhibition of tRNA metabolism|down-regulation of tRNA metabolic process|downregulation of tRNA metabolic process|down regulation of tRNA metabolism|down regulation of tRNA metabolic process|inhibition of tRNA metabolic process|downregulation of tRNA metabolism|down-regulation of tRNA metabolism|negative regulation of tRNA metabolism Any process that stops, prevents or reduces the frequency, rate or extent of tRNA metabolic process. GO:1903326 regulation of tRNA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903326 regulation of tRNA metabolism Any process that modulates the frequency, rate or extent of tRNA metabolic process. GO:1903325 positive regulation of snoRNA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903325 up-regulation of snoRNA metabolism|up regulation of snoRNA metabolic process|upregulation of snoRNA metabolism|upregulation of snoRNA metabolic process|up regulation of snoRNA metabolism|activation of snoRNA metabolism|positive regulation of snoRNA metabolism|up-regulation of snoRNA metabolic process|activation of snoRNA metabolic process Any process that activates or increases the frequency, rate or extent of snoRNA metabolic process. GO:1903324 negative regulation of snoRNA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903324 inhibition of snoRNA metabolism|down-regulation of snoRNA metabolic process|downregulation of snoRNA metabolic process|down regulation of snoRNA metabolism|down regulation of snoRNA metabolic process|downregulation of snoRNA metabolism|inhibition of snoRNA metabolic process|negative regulation of snoRNA metabolism|down-regulation of snoRNA metabolism Any process that stops, prevents or reduces the frequency, rate or extent of snoRNA metabolic process. GO:1903323 regulation of snoRNA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903323 regulation of snoRNA metabolism Any process that modulates the frequency, rate or extent of snoRNA metabolic process. CHEBI:167057 Monolysocardiolipin(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_167057 GO:1903322 positive regulation of protein modification by small protein conjugation or removal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903322 up-regulation of protein modification by small protein conjugation or removal|activation of protein modification by small protein conjugation or removal|up regulation of protein modification by small protein conjugation or removal|upregulation of protein modification by small protein conjugation or removal Any process that activates or increases the frequency, rate or extent of protein modification by small protein conjugation or removal. GO:1903321 negative regulation of protein modification by small protein conjugation or removal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903321 down-regulation of protein modification by small protein conjugation or removal|downregulation of protein modification by small protein conjugation or removal|down regulation of protein modification by small protein conjugation or removal|inhibition of protein modification by small protein conjugation or removal Any process that stops, prevents or reduces the frequency, rate or extent of protein modification by small protein conjugation or removal. GO:1903331 positive regulation of iron-sulfur cluster assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903331 upregulation of iron-sulfur cluster biosynthesis|upregulation of iron-sulfur cluster assembly|up regulation of iron-sulphur cluster assembly|activation of iron-sulphur cluster assembly|positive regulation of iron-sulphur cluster assembly|up-regulation of iron-sulfur cluster biosynthesis|up-regulation of iron-sulfur cluster assembly|activation of iron-sulfur cluster assembly|activation of iron-sulfur cluster biosynthesis|up-regulation of iron-sulphur cluster assembly|positive regulation of iron-sulfur cluster biosynthesis|up regulation of iron-sulfur cluster biosynthesis|up regulation of iron-sulfur cluster assembly|upregulation of iron-sulphur cluster assembly Any process that activates or increases the frequency, rate or extent of iron-sulfur cluster assembly. GO:1903330 negative regulation of iron-sulfur cluster assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903330 down regulation of iron-sulphur cluster assembly|down regulation of iron-sulfur cluster biosynthesis|down regulation of iron-sulfur cluster assembly|inhibition of iron-sulfur cluster assembly|downregulation of iron-sulphur cluster assembly|inhibition of iron-sulfur cluster biosynthesis|down-regulation of iron-sulphur cluster assembly|negative regulation of iron-sulphur cluster assembly|inhibition of iron-sulphur cluster assembly|down-regulation of iron-sulfur cluster biosynthesis|negative regulation of iron-sulfur cluster biosynthesis|down-regulation of iron-sulfur cluster assembly|downregulation of iron-sulfur cluster biosynthesis|downregulation of iron-sulfur cluster assembly Any process that stops, prevents or reduces the frequency, rate or extent of iron-sulfur cluster assembly. CHEBI:133631 1-palmitoyl-2-icosatrienoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133631 GO:1903339 negative regulation of cell wall organization or biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903339 down-regulation of cell wall organization or biogenesis|downregulation of cell wall organisation or biogenesis|negative regulation of cell wall organization or biogenesis at cellular level|inhibition of cellular cell wall organisation or biogenesis|down-regulation of cell wall organization or biogenesis at cellular level|negative regulation of cellular cell wall organization or biogenesis|down-regulation of cellular cell wall organization or biogenesis|down regulation of cell wall organisation or biogenesis|inhibition of cell wall organisation or biogenesis|downregulation of cell wall organization or biogenesis|inhibition of cellular cell wall organization or biogenesis|down regulation of cell wall organization or biogenesis|inhibition of cell wall organization or biogenesis|downregulation of cell wall organization or biogenesis at cellular level|down regulation of cellular cell wall organisation or biogenesis|down regulation of cell wall organization or biogenesis at cellular level|inhibition of cell wall organization or biogenesis at cellular level|downregulation of cellular cell wall organisation or biogenesis|negative regulation of cell wall organisation or biogenesis|down regulation of cellular cell wall organization or biogenesis|down-regulation of cell wall organisation or biogenesis|downregulation of cellular cell wall organization or biogenesis|down-regulation of cellular cell wall organisation or biogenesis|negative regulation of cellular cell wall organisation or biogenesis Any process that stops, prevents or reduces the frequency, rate or extent of cell wall organization or biogenesis. GO:1903338 regulation of cell wall organization or biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903338 regulation of cell wall organisation or biogenesis|regulation of cell wall organization or biogenesis at cellular level|regulation of cellular cell wall organisation or biogenesis|regulation of cellular cell wall organization or biogenesis Any process that modulates the frequency, rate or extent of cell wall organization or biogenesis. GO:1903337 positive regulation of vacuolar transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903337 upregulation of vacuolar transport|up-regulation of vacuolar transport|activation of vacuolar transport|up regulation of vacuolar transport Any process that activates or increases the frequency, rate or extent of vacuolar transport. GO:1903336 negative regulation of vacuolar transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903336 inhibition of vacuolar transport|down-regulation of vacuolar transport|downregulation of vacuolar transport|down regulation of vacuolar transport Any process that stops, prevents or reduces the frequency, rate or extent of vacuolar transport. GO:1903335 regulation of vacuolar transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903335 Any process that modulates the frequency, rate or extent of vacuolar transport. GO:1903334 positive regulation of protein folding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903334 positive regulation of glycoprotein-specific chaperone activity|activation of co-chaperonin activity|up regulation of chaperonin-mediated tubulin folding|up regulation of glycoprotein-specific chaperone activity|up-regulation of co-chaperone activity|positive regulation of chaperonin-mediated tubulin folding|positive regulation of beta-tubulin folding|positive regulation of chaperone activity|up regulation of beta-tubulin folding|positive regulation of co-chaperonin activity|up-regulation of chaperonin ATPase activity|up-regulation of protein folding|up regulation of chaperone activity|up-regulation of protein complex assembly, multichaperone pathway|upregulation of non-chaperonin molecular chaperone ATPase activity|up regulation of alpha-tubulin folding|up regulation of co-chaperonin activity|activation of chaperonin-mediated tubulin folding|positive regulation of alpha-tubulin folding|upregulation of co-chaperone activity|activation of chaperonin ATPase activity|upregulation of glycoprotein-specific chaperone activity|activation of protein complex assembly, multichaperone pathway|upregulation of protein folding|activation of alpha-tubulin folding|up-regulation of chaperonin-mediated tubulin folding|upregulation of beta-tubulin folding|up-regulation of non-chaperonin molecular chaperone ATPase activity|positive regulation of chaperonin ATPase activity|upregulation of chaperone activity|upregulation of co-chaperonin activity|positive regulation of protein complex assembly, multichaperone pathway|up regulation of chaperonin ATPase activity|up regulation of protein complex assembly, multichaperone pathway|up-regulation of alpha-tubulin folding|up-regulation of glycoprotein-specific chaperone activity|up regulation of co-chaperone activity|activation of non-chaperonin molecular chaperone ATPase activity|upregulation of chaperonin-mediated tubulin folding|positive regulation of co-chaperone activity|up-regulation of beta-tubulin folding|up regulation of protein folding|up-regulation of chaperone activity|activation of protein folding|up-regulation of co-chaperonin activity|positive regulation of non-chaperonin molecular chaperone ATPase activity|activation of glycoprotein-specific chaperone activity|upregulation of chaperonin ATPase activity|activation of co-chaperone activity|upregulation of protein complex assembly, multichaperone pathway|upregulation of alpha-tubulin folding|up regulation of non-chaperonin molecular chaperone ATPase activity|activation of beta-tubulin folding|activation of chaperone activity Any process that activates or increases the frequency, rate or extent of protein folding. GO:1903333 negative regulation of protein folding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903333 downregulation of non-chaperonin molecular chaperone ATPase activity|negative regulation of chaperone activity|down regulation of alpha-tubulin folding|down-regulation of chaperone activity|inhibition of chaperonin ATPase activity|negative regulation of co-chaperonin activity|inhibition of protein complex assembly, multichaperone pathway|down-regulation of co-chaperonin activity|inhibition of protein folding|down regulation of non-chaperonin molecular chaperone ATPase activity|downregulation of alpha-tubulin folding|downregulation of glycoprotein-specific chaperone activity|inhibition of co-chaperone activity|down-regulation of chaperonin-mediated tubulin folding|negative regulation of chaperonin-mediated tubulin folding|downregulation of beta-tubulin folding|down regulation of glycoprotein-specific chaperone activity|downregulation of chaperone activity|downregulation of co-chaperonin activity|inhibition of non-chaperonin molecular chaperone ATPase activity|negative regulation of chaperonin ATPase activity|down-regulation of chaperonin ATPase activity|down regulation of beta-tubulin folding|negative regulation of alpha-tubulin folding|down-regulation of protein complex assembly, multichaperone pathway|down-regulation of alpha-tubulin folding|down regulation of chaperone activity|negative regulation of protein complex assembly, multichaperone pathway|down regulation of co-chaperonin activity|down regulation of co-chaperone activity|down regulation of protein folding|inhibition of glycoprotein-specific chaperone activity|downregulation of co-chaperone activity|inhibition of chaperonin-mediated tubulin folding|inhibition of beta-tubulin folding|downregulation of protein folding|inhibition of chaperone activity|downregulation of chaperonin ATPase activity|inhibition of co-chaperonin activity|downregulation of protein complex assembly, multichaperone pathway|negative regulation of non-chaperonin molecular chaperone ATPase activity|down-regulation of non-chaperonin molecular chaperone ATPase activity|down regulation of chaperonin ATPase activity|inhibition of alpha-tubulin folding|down regulation of chaperonin-mediated tubulin folding|down regulation of protein complex assembly, multichaperone pathway|down-regulation of co-chaperone activity|negative regulation of co-chaperone activity|down-regulation of glycoprotein-specific chaperone activity|negative regulation of glycoprotein-specific chaperone activity|down-regulation of protein folding|downregulation of chaperonin-mediated tubulin folding|down-regulation of beta-tubulin folding|negative regulation of beta-tubulin folding Any process that stops, prevents or reduces the frequency, rate or extent of protein folding. GO:1903332 regulation of protein folding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903332 regulation of alpha-tubulin folding|regulation of non-chaperonin molecular chaperone ATPase activity|regulation of glycoprotein-specific chaperone activity|regulation of beta-tubulin folding|regulation of chaperone activity|regulation of co-chaperonin activity|regulation of co-chaperone activity|regulation of chaperonin ATPase activity|regulation of protein complex assembly, multichaperone pathway|regulation of chaperonin-mediated tubulin folding Any process that modulates the frequency, rate or extent of protein folding. GO:1903342 negative regulation of meiotic DNA double-strand break formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903342 down regulation of meiotic DNA double-strand break formation|downregulation of meiotic DNA double-strand break formation|down-regulation of meiotic DNA double-strand break formation|inhibition of meiotic DNA double-strand break formation Any process that stops, prevents or reduces the frequency, rate or extent of meiotic DNA double-strand break formation. GO:1903341 regulation of meiotic DNA double-strand break formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903341 Any process that modulates the frequency, rate or extent of meiotic DNA double-strand break formation. GO:1903340 positive regulation of cell wall organization or biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903340 upregulation of cellular cell wall organization or biogenesis|up-regulation of cell wall organization or biogenesis|up regulation of cellular cell wall organisation or biogenesis|activation of cell wall organization or biogenesis|activation of cellular cell wall organisation or biogenesis|positive regulation of cellular cell wall organisation or biogenesis|positive regulation of cell wall organisation or biogenesis|up-regulation of cell wall organization or biogenesis at cellular level|activation of cell wall organization or biogenesis at cellular level|up regulation of cell wall organisation or biogenesis|up regulation of cellular cell wall organization or biogenesis|activation of cellular cell wall organization or biogenesis|positive regulation of cellular cell wall organization or biogenesis|up regulation of cell wall organization or biogenesis|up-regulation of cellular cell wall organisation or biogenesis|positive regulation of cell wall organization or biogenesis at cellular level|upregulation of cell wall organisation or biogenesis|up regulation of cell wall organization or biogenesis at cellular level|up-regulation of cellular cell wall organization or biogenesis|upregulation of cellular cell wall organisation or biogenesis|upregulation of cell wall organization or biogenesis|activation of cell wall organisation or biogenesis|up-regulation of cell wall organisation or biogenesis|upregulation of cell wall organization or biogenesis at cellular level Any process that activates or increases the frequency, rate or extent of cell wall organization or biogenesis. NCBITaxon:1445966 Gnetidae organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_1445966 CHEBI:87420 lipid A 4'-(2-aminoethyl diphosphate) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87420 CHEBI:63455 tetronic acid derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63455 CHEBI:63454 pentonic acid derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63454 CHEBI:87424 lipid A 1,4'-bis(2-aminoethyl diphosphate) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87424 CHEBI:63459 shionone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63459 CHEBI:87425 juvenile hormone I acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87425 CHEBI:63458 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63458 CHEBI:143098 Gp[2'-5']Ap[3'](3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_143098 CHEBI:143097 Gp[2'-5']Ap[3'] biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_143097 CHEBI:143095 10-hydroxyoctadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_143095 CHEBI:143093 2'-3'-cGAMP(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_143093 CHEBI:143092 1-palmitoyl-2-(9,10-epoxyoctadecanoyl)-sn-glycero-3-phospho-L-serine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_143092 CHEBI:63462 glutinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63462 CHEBI:63461 achilleol B biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63461 CHEBI:63460 parkeol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63460 CHEBI:63466 beta-seco-amyrin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63466 CHEBI:63465 marneral biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63465 CHEBI:87410 N-docosanoylglycinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87410 CHEBI:63464 alpha-seco-amyrin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63464 CHEBI:63463 baccharis oxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63463 CHEBI:87415 7-O-[(2-aminoethyl)phosphoryl]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87415 CHEBI:63469 3-hydroxy-3-phenylpropionate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63469 CHEBI:87414 N-hexacosanoylglycinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87414 CHEBI:63468 tirucalla-7,24-dien-3beta-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63468 CHEBI:63467 delta-amyrin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63467 CHEBI:143087 1-stearoyl-2-(9,10-epoxyoctadecanoyl)-sn-glycero-3-phospho-L-serine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_143087 CHEBI:143084 organometalloidal compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_143084 CHEBI:143081 D-homoserine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_143081 CHEBI:143080 D-norleucine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_143080 CHEBI:63473 aromatic amino-acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63473 CHEBI:63471 branched-chain amino-acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63471 CHEBI:63470 sulfur-containing amino-acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63470 CHEBI:63477 iodothyroninate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63477 CHEBI:63476 4-carboxylato-4'-sulfonatoazobenzene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63476 CHEBI:143089 10-hydroxyoctadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_143089 CHEBI:63475 ectoinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63475 CHEBI:63474 arsonoacetic acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63474 CHEBI:87447 5-epi-valiolone 7-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87447 CHEBI:87449 trans-caffeoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87449 CHEBI:63488 beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAcl-(1->4)-beta-D-GlcNAc-yl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63488 CHEBI:87433 (R)-2-hydroxy-4-methylpentanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87433 CHEBI:143079 D-leucine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_143079 CHEBI:87435 11-cis-retinoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87435 CHEBI:87436 4-methylpent-2-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87436 CHEBI:87438 lithocholyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87438 CHEBI:63490 explosive biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63490 CHEBI:87460 6-hydroxy-N-methylmyosmine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87460 CHEBI:87467 prenyl-FMNH2(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87467 CL:1001225 kidney collecting duct cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001225 PR:000001221 endothelin-1 receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001221 ETA-R|Gpcr10|ET-AR|ETA|endothelin receptor A|endothelin A receptor|EDNRA|ETRA|ET-A An endothelin receptor that is a translation product of the human EDNRA gene or a 1:1 ortholog thereof. The active form binds endothelin 1 (ET-1) and ET-2 with much higher affinity than ET-3. PR:000001223 gastrin-releasing peptide receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001223 GRP-preferring bombesin receptor|GRPR|GRP-R A bombesin receptor that is a translation product of the human GRPR gene or a 1:1 ortholog thereof. The preferred ligand is gastrin releasing peptide. PR:000001225 growth hormone secretagogue receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001225 GHS-R|GH-releasing peptide receptor|GHSR|GHRP|ghrelin receptor A growth hormone secretagogue/motilin receptor that is a translation product of the human GHSR gene or a 1:1 ortholog thereof. Although its preferred ligand is ghrelin, it also binds other growth hormone releasing peptides and some nonpeptide ligands. CHEBI:87451 dihydrocaffeoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87451 CHEBI:157698 glucohexaose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_157698 CHEBI:87488 short-chain 2,3-trans-enoyl CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87488 CHEBI:87487 short-chain 3-substituted propanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87487 PR:000001203 C-C chemokine receptor type 7 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001203 CCR-7|CDw197|EVI1|EBV-induced G-protein coupled receptor 1|CD197|C-C CKR-7|BLR2|CC-CKR-7|MIP-3 beta receptor|EBI1|CCR7|epstein-Barr virus-induced G-protein coupled receptor 1|CMKBR7|chemokine receptor CCR7|Ebi1h A chemokine receptor that is a translation product of the human CCR7 gene or a 1:1 ortholog thereof. The preferred ligands are CCL19 and CCL21. PR:000001202 C-C chemokine receptor type 6 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001202 CCR-6|GPR-CY4|LARC receptor|STRL22|GPRCY4|chemokine receptor-like 3|CD196|C-C CKR-6|G-protein coupled receptor 29|CKRL3|DRY6|GPR29|CKR-L3|CC-CKR-6|KY411|CCR6|CMKBR6|chemokine receptor CCR6 A chemokine receptor that is a translation product of the human CCR6 gene or a 1:1 ortholog thereof. The preferred ligand is CCL20. PR:000001206 CX3C chemokine receptor 1 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001206 V28|fractalkine receptor|CMK-BRL-1|CMKBRL1|C-X3-C CKR-1|G-protein coupled receptor 13|GPR13|CX3CR1|CMK-BRL1|beta chemokine receptor-like 1|chemokine receptor CX3CR1 A chemokine receptor that is a translation product of the human CX3CR1 gene or a 1:1 ortholog thereof. The preferred ligand is CX3CL1. PR:000001208 C-X-C chemokine receptor type 4 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001208 pre-B-cell-derived chemokine receptor|Cmkar4|FB22|LESTR|leukocyte-derived seven transmembrane domain receptor|LCR1|chemokine receptor CXCR4|stromal cell-derived factor 1 receptor|Sdf1r|NPYRL|CXCR4|PB-CKR|CD184|CXCR-4|fusin|HM89|SDF-1 receptor|CXC-R4 A chemokine receptor that is a translation product of the human CXCR4 gene or a 1:1 ortholog thereof. The preferred ligand is CXCL12. CHEBI:157685 primary alkyl sulfate ester(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_157685 CHEBI:87475 (R)-2-hydroxybutanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87475 CHEBI:87474 (R)-2-hydroxybutanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87474 CHEBI:87476 (25R)-7alpha,26-dihydroxycholest-4-en-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87476 PR:000001212 chemokine XC receptor 1 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001212 SCM1 receptor|GPR5|CCXCR1|chemokine receptor XCR1|lymphotactin receptor|G-protein coupled receptor 5|XC chemokine receptor 1|XCR1 A chemokine receptor that is a translation product of the human XCR1 gene or a 1:1 ortholog thereof. The preferred ligands are XCL1 and XCL2. GO:0097079 selenite:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097079 selenite:hydrogen symporter activity|selenite:H+ symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: selenite(out) + H+(out) = selenite(in) + H+(in). GO:0097078 FAL1-SGD1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097078 A protein complex involved in the 18S rRNA biogenesis. In S. cerevisiae this complex consists of Fal1p and Sgd1p and in humans this complex consists of NOM1 and eIF4AIII subunits. GO:0097075 interferon regulatory factor 3-interferon regulatory factor 7 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097075 IRF3:IRF7 complex An interferon regulatory factor complex that consists of a heterodimer of interferon regulatory factor 3 and interferon regulatory factor 7. GO:0097074 interferon regulatory factor 7 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097074 IRF7:IRF7 complex An interferon regulatory factor complex that consists of a homodimer of interferon regulatory factor 7. GO:0097077 copper ion sensor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097077 Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of copper(I) (Cu+). GO:0097076 transforming growth factor beta activated kinase 1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097076 TAK1 kinase complex A protein complex that possesses protein kinase activity and activates the I-kappa B kinase complex (IKK) and mitogen-activated protein (MAP) kinases in response to TRAF6 signaling. It comprises the catalytic subunit TAK1 complexed to the regulatory subunits, termed TABs (TAK1-binding subunits). GO:0097071 interferon regulatory factor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097071 IRF complex A protein complex that consists of two interferon regulatory proteins (IRFs); may be homodimeric or heterodimeric. The activation of a latent closed conformation of IRF in the cytoplasm is triggered by phosphorylation of Ser/Thr residues in a C-terminal region. Phosphorylation stimulates the C-terminal autoinhibitory domain to attain a highly extended conformation triggering dimerization through extensive contacts to a second subunit. GO:0097070 ductus arteriosus closure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097070 The morphogenesis process in which the ductus arteriosus changes to no longer permit blood flow after birth. The ductus arteriosus is the shunt between the aorta and the pulmonary artery which allows blood to bypass the fetus' lungs. GO:0097073 interferon regulatory factor 5 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097073 IRF5:IRF5 complex An interferon regulatory factor complex that consists of a homodimer of interferon regulatory factor 5. CHEBI:38409 2,4-dichloromuconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38409 GO:0097072 interferon regulatory factor 3 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097072 IRF3:IRF3 complex An interferon regulatory factor complex that consists of a homodimer of interferon regulatory factor 3. CHEBI:38408 chloromuconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38408 CHEBI:38407 muconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38407 CHEBI:14434 imidazole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_14434 GO:0097089 methyl-branched fatty acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097089 methyl-branched fatty acid metabolism The chemical reactions and pathways involving methyl-branched fatty acids, aliphatic monocarboxylic acids with methyl branches on the main chain. GO:0097086 amniotic stem cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097086 The process whereby a relatively unspecialized cell acquires specialized features of an amniotic stem cell. An amniotic stem cell is a mesenchymal stem cell extracted from amniotic fluid. Amniotic stem cells are able to differentiate into various tissue types such as skin, cartilage, cardiac tissue, nerves, muscle, and bone. GO:0097085 interferon regulatory factor 3-interferon regulatory factor 5 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097085 IRF3:IRF5 complex An interferon regulatory factor complex that consists of a heterodimer of interferon regulatory factor 3 and interferon regulatory factor 5. GO:0097088 interleukin-17F production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0097088 IL-17F production The appearance of interleukin-17F due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0097087 interleukin-17A production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0097087 IL-17A production|interleukin-17A biosynthetic process The appearance of interleukin-17A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0097082 vascular associated smooth muscle cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097082 vascular smooth muscle cell fate specification The process in which a cell becomes capable of differentiating autonomously into a vascular smooth muscle cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels. GO:0097081 vascular associated smooth muscle cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097081 vascular smooth muscle cell fate commitment The commitment of cells to a vascular smooth muscle cell fate and their capacity to differentiate into vascular smooth muscle cells. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels. GO:0097084 vascular associated smooth muscle cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097084 vascular smooth muscle cell development The process aimed at the progression of a vascular smooth muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels. GO:0097083 vascular associated smooth muscle cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097083 vascular smooth muscle cell fate determination The process in which a cell becomes capable of differentiating autonomously into a vascular smooth muscle cell regardless of its environment; upon determination, the cell fate cannot be reversed. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels. GO:0097080 plasma membrane selenite transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097080 plasma membrane hydrogenselenite transport The directed movement of inorganic selenite (HSeO3-1 at physiological pH) across a plasma membrane. CHEBI:14428 hyponitrous acid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_14428 CHEBI:38412 2,4-dichloromuconate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38412 CHEBI:38419 saturated organic heterobicyclic parent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38419 CHEBI:38418 1,3-thiazoles biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38418 CHEBI:38411 chlorocarboxylic acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38411 GO:0097057 TRAF2-GSTP1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097057 A protein complex comprising tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and glutathione S-transferase pi 1 (GSTP1). This complex is thought to disrupt the TNF signaling cascade, thus down-regulating inflammatory responses. GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097056 selenocysteinyl-tRNA(Sec) anabolism|selenocysteinyl-tRNA(Sec) biosynthesis|selenocysteinyl-tRNA(Sec) synthesis|selenocysteinyl-tRNA(Sec) formation The chemical reactions and pathways resulting in the formation of selenocysteinyl-tRNA(Sec). This process occurs through the following steps: a unique serine-tRNA with a UGA recognizing anticodon is first aminoacylated with serine; this is then phosphorylated by phosphoseryl-tRNA[Ser]Sec kinase; lastly, selenium is swapped for the phosphate on the serine. GO:0097059 CNTFR-CLCF1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097059 sCNTFR-CLC complex A protein complex that is composed of two soluble ciliary neurotrophic factor receptor alpha subunits (product of the CNTFR gene) and two molecules of cardiotrophin-like cytokine factor 1 (product of the CLCF1 gene). The complex is secreted into the extracellular space. GO:0097058 CRLF-CLCF1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097058 CLF-CLC complex A heterodimeric protein complex that is composed of cardiotrophin-like cytokine factor 1 (product of the CLCF1 gene) and cytokine receptor-like factor 1 (product of the CRLF gene) and is secreted into the extracellular space. The CRLF-CLCF1 complex is a ligand for the ciliary neurotrophic factor (CNTF) receptor complex. GO:0097053 L-kynurenine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097053 L-kynurenine degradation|L-kynurenine breakdown|L-kynurenine catabolism The chemical reactions and pathways resulting in the breakdown of L-kynurenine, the L-enantiomer of the amino acid kynurenine (3-(2-aminobenzoyl)-alanine). GO:0097052 L-kynurenine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097052 L-kynurenine metabolism The chemical reactions and pathways involving L-kynurenine, the L-enantiomer of the amino acid kynurenine (3-(2-aminobenzoyl)-alanine). GO:0097055 agmatine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097055 agmatine anabolism|agmatine synthesis|agmatine formation|agmatine biosynthesis The chemical reactions and pathways resulting in the formation of agmatine ((4-aminobutyl)guanidine, NH2-CH2-CH2-CH2-CH2-NH-C(-NH2)(=NH)). Agmatine is the decarboxylation product of the amino acid arginine and is an intermediate in polyamine biosynthesis. It is synthesized in the brain, stored in synaptic vesicles, accumulated by uptake, released by membrane depolarization, and inactivated by agmatinase. GO:0097054 L-glutamate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097054 L-glutamate anabolism|L-glutamate synthesis|L-glutamate formation|L-glutamate biosynthesis The chemical reactions and pathways resulting in the formation of L-glutamate, the L enantiomer anion of 2-aminopentanedioic acid. UBERON:0011693 extraembryonic portion of umbilical artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011693 extraembryonic umbilical artery GO:0097051 establishment of protein localization to endoplasmic reticulum membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097051 establishment of protein localisation in endoplasmic reticulum membrane|establishment of protein localization in endoplasmic reticulum membrane The directed movement of a protein to a specific location in the endoplasmic reticulum membrane. GO:0097050 type B pancreatic cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097050 type B pancreatic cell apoptosis|pancreatic B cell apoptosis|pancreatic beta cell apoptosis Any apoptotic process in a type B pancreatic cell, a cell located towards center of the islets of Langerhans that secretes insulin. UBERON:0011697 right extraembryonic umbilical artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011697 extraembryonic umbilical artery right UBERON:0011696 left extraembryonic umbilical artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011696 extraembryonic umbilical artery left UBERON:0011695 embryonic cardiovascular system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011695 conceptus cardiovascular system|embryonic circulatory system|fetal circulatory system A cardiovascular system that is part of a conceptus. CL:1001320 urethra cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001320 GO:0097068 response to thyroxine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097068 response to T4|response to T4 stimulus|response to thyroxine stimulus A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroxine stimulus. GO:0097067 cellular response to thyroid hormone stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097067 A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus. GO:0097069 cellular response to thyroxine stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097069 cellular response to T4 stimulus A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroxine stimulus. GO:0097064 ncRNA export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097064 non-coding RNA export from nucleus The directed movement of a non-coding RNA transcript (ncRNA) from the nucleus to the cytoplasm. GO:0097063 cadmium ion sensor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097063 Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of cadmium (Cd++). GO:0097066 response to thyroid hormone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097066 response to thyroid hormone stimulus A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus. GO:0097065 anterior head development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097065 The process whose specific outcome is the progression of the anterior part of the head over time, from its formation to the mature structure. GO:0097060 synaptic membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0097060 A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. GO:0097062 dendritic spine maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097062 The organization process that preserves a dendritic spine in a stable functional or structural state. A dendritic spine is a specialized protrusion from a neuronal dendrite and is involved in synaptic transmission. CL:1001319 bladder cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001319 GO:0097061 dendritic spine organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097061 dendritic spine organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dendritic spine. A dendritic spine is a specialized protrusion from a neuronal dendrite and is involved in synaptic transmission. CL:1001318 renal interstitial pericyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001318 UBERON:0011679 proximal tarsal bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011679 A tarsal bone that connected_to a hindlimb zeugopod skeleton. CHEBI:63403 sedoheptulose derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63403 CHEBI:63402 ketose derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63402 UBERON:0011677 trunk vertebra biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011677 thoracolumbar vertebra|presacral vertebra A vertebra in the trunk region. For tetrapods, includes lumbar and thoracic vertebrae. Excludes caudal/coccygeal vertebra, which are located posteriorly. In tetrapods this includes thoracic, lumbar and sacral vertebrae, and excludes the cervical vertebrae, which are located anteriorly. CHEBI:63401 ketooctose derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63401 CHEBI:63407 ketotriose derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63407 CHEBI:63405 ketopentose derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63405 CHEBI:63409 pentose derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63409 UBERON:0035642 laryngeal nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035642 Any nerve that innervates the larynx. CHEBI:63410 all-trans-retinyl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63410 CHEBI:63415 glycodiaosylceramide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63415 CHEBI:63413 triose derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63413 UBERON:0035639 ocular adnexa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035639 appendages of the eye|set of accessory visual structures|adnexa oculi|appendage of eye|accessory parts of orbital region|structurae oculi accessoriae|accessory visual structures set|accessory visual structures|eye adnexa|adnexal parts of orbital region The parts of the orbital region that are outside of the the eyeball, including the lacrimal apparatus, the extraocular muscles and the eyelids, eyelashes, eyebrows and the conjunctiva CHEBI:63417 UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altrose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63417 CHEBI:63416 4-amino-5-ammoniomethyl-2-methylpyrimidine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63416 UBERON:0035650 nerve of clitoris biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035650 clitoral nerve|clitoris nerve Any nerve that innervates the clitoris. UBERON:0035651 glans biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035651 CHEBI:63422 UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altrose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63422 CHEBI:63421 beta-L-altrose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63421 CHEBI:63420 UDP-4-amino-4,6-dideoxy-L-N-acetyl-beta-L-altrosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63420 CHEBI:63426 glucosylglycerol derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63426 CHEBI:63425 galactosylglycerol derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63425 UBERON:0035649 nerve of penis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035649 penile nerve|penis nerve Any nerve that innervates the penis. CHEBI:63424 glycosyl alditol derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63424 UBERON:0035648 nerve innervating pinna biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035648 auricular nerve Any nerve that innervates the pinna. CHEBI:63423 alditol derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63423 CHEBI:63428 digalactosylglycerol derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63428 CHEBI:63427 glycosylglycerol derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63427 OBO:GOCHE_78295 substance with food component role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_78295 GO:0097097 nasal suture morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097097 internasal suture morphogenesis The process in which the nasal suture is generated and organized. GO:0097096 facial suture morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097096 The process in which any suture between facial bones is generated and organized. GO:0097099 structural constituent of albumen biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097099 structural constituent of egg white The action of a molecule that contributes to the structural integrity of albumen (also called egg white). Albumen is the clear liquid contained within an egg and consists of water and proteins, among which are ovomucin and ovomucoid. It protects the egg yolk and provides additional nutrition for the growth of the embryo. GO:0097098 DNA/RNA hybrid annealing activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097098 Facilitates the base-pairing of single-stranded RNA to double-stranded DNA resulting in the formation of R-loops. GO:0097093 polyacyltrehalose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097093 polyacyltrehalose biosynthesis|polyacyltrehalose anabolism|polyacyltrehalose synthesis|polyacyltrehalose formation The chemical reactions and pathways resulting in the formation of polyacyltrehalose, a pentaacylated, trehalose-based glycolipid. GO:0097092 polyacyltrehalose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097092 polyacyltrehalose metabolism The chemical reactions and pathways involving polyacyltrehalose, a pentaacylated, trehalose-based glycolipid. GO:0097095 frontonasal suture morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097095 nasofrontal suture morphogenesis The process in which the frontonasal suture, between frontal and nasal bones, is generated and organized. GO:0097094 craniofacial suture morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097094 The process in which any suture between cranial and/or facial bones is generated and organized. CHEBI:63432 galactitol derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63432 GO:0097091 synaptic vesicle clustering biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0097091 The process that results in grouping synaptic vesicles in presynaptic structures. GO:0097090 presynaptic membrane organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097090 presynaptic membrane organisation|pre-synaptic membrane organization A process which results in the assembly, arrangement of constituent parts, or disassembly of a presynaptic membrane, including any proteins associated with the membrane, but excluding other cellular components. A presynaptic membrane is a specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction. CHEBI:63430 hexitol derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63430 CHEBI:63437 aldaric acid derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63437 CHEBI:63436 carbohydrate acid derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63436 CHEBI:63435 tetritol derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63435 CHEBI:63434 pentitol derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63434 CHEBI:63438 hexaric acid derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63438 CHEBI:63444 viridiflorene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63444 CHEBI:63443 alpha-guaiene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63443 CHEBI:63442 hexonic acid derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63442 CHEBI:63441 aldonic acid derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63441 CHEBI:63447 delta-guaiene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63447 CHEBI:63446 (-)-cubebol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63446 CHEBI:63445 5-epi-alpha-selinene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63445 GO:0048068 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048068 GO:0048067 cuticle pigmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048067 Establishment of a pattern of pigment in the cuticle of an organism. GO:0048066 developmental pigmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048066 pigmentation during development The developmental process that results in the deposition of coloring matter in an organism, tissue or cell. GO:0048065 male courtship behavior, veined wing extension biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048065 male courtship behaviour, veined wing extension|male courtship behavior, wing extension|male courtship behaviour, wing extension The process during courtship where the male insect extends his wings. An example of this process is found in Drosophila melanogaster. GO:0048064 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048064 GO:0048063 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048063 GO:0048062 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048062 GO:0048061 positive gravitaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048061 positive geotactic behavior|positive geotactic behaviour|positive taxis in response to gravity|positive taxis in response to gravitytaxis in response to gravitational stimulus|positive gravitactic behavior|positive gravitactic behaviour The directed movement of a motile cell or organism towards the source of gravity. GO:1903229 xanthosine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903229 xanthosine anabolism|xanthosine synthesis|xanthosine formation|xanthosine biosynthesis The chemical reactions and pathways resulting in the formation of xanthosine. GO:0014728 regulation of the force of skeletal muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014728 Any process that modulates the frequency, rate or extent of the force of skeletal muscle contraction. The force of skeletal muscle contraction is produced by acto-myosin interaction processes through the formation of cross bridges. GO:1903228 xanthosine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903228 xanthosine catabolism|xanthosine degradation|xanthosine breakdown The chemical reactions and pathways resulting in the breakdown of xanthosine. GO:0014727 positive regulation of extraocular skeletal muscle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014727 Any process that activates, maintains or increases the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. GO:1903227 xanthosine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903227 xanthosine metabolism The chemical reactions and pathways involving xanthosine. GO:0014726 negative regulation of extraocular skeletal muscle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014726 Any process that stops, prevents, or reduces the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. CHEBI:133738 2-hydroxyhexanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133738 GO:0014725 regulation of extraocular skeletal muscle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014725 Any process that modulates the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. GO:1903226 positive regulation of endodermal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903226 up regulation of endoderm cell differentiation|upregulation of endodermal cell differentiation|activation of endoderm cell differentiation|positive regulation of endoderm cell differentiation|up regulation of endodermal cell differentiation|activation of endodermal cell differentiation|up-regulation of endoderm cell differentiation|upregulation of endoderm cell differentiation|up-regulation of endodermal cell differentiation Any process that activates or increases the frequency, rate or extent of endodermal cell differentiation. GO:1903225 negative regulation of endodermal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903225 down regulation of endodermal cell differentiation|negative regulation of endoderm cell differentiation|down-regulation of endoderm cell differentiation|downregulation of endodermal cell differentiation|inhibition of endoderm cell differentiation|down-regulation of endodermal cell differentiation|inhibition of endodermal cell differentiation|down regulation of endoderm cell differentiation|downregulation of endoderm cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of endodermal cell differentiation. GO:1903224 regulation of endodermal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903224 regulation of endoderm cell differentiation Any process that modulates the frequency, rate or extent of endodermal cell differentiation. GO:1903223 positive regulation of oxidative stress-induced neuron death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903223 up-regulation of neuron death in response to oxidative stress|activation of neuron death in response to oxidative stress|upregulation of neuronal cell death in response to oxidative stress|up regulation of oxidative stress-induced neuron death|activation of oxidative stress-induced neuron death|up regulation of neuronal cell death in response to oxidative stress|positive regulation of neuron death in response to oxidative stress|up regulation of neuron death in response to oxidative stress|positive regulation of neuronal cell death in response to oxidative stress|activation of neuronal cell death in response to oxidative stress|up-regulation of oxidative stress-induced neuron death|upregulation of neuron death in response to oxidative stress|upregulation of oxidative stress-induced neuron death|up-regulation of neuronal cell death in response to oxidative stress|sensitization of neuron to oxidative stress-induced cell death Any process that activates or increases the frequency, rate or extent of oxidative stress-induced neuron death. GO:0048069 eye pigmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048069 Wikipedia:Eye_color Establishment of a pattern of pigment in the eye of an organism. GO:1903222 quinolinic acid transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903222 The process in which quinolinic acid is transported across a membrane. GO:0014729 regulation of the velocity of shortening of skeletal muscle modulating contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014729 regulation of the velocity of shortening of skeletal muscle during contraction Any process that modulates velocity of shortening of a skeletal muscle contraction. The shortening leads to reduction of the length of muscle fibers and sarcomeres. GO:1903232 melanosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903232 melanosome formation The aggregation, arrangement and bonding together of a set of components to form a melanosome, a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. GO:0014720 tonic skeletal muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014720 A process in which force is generated within tonic skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The tonic skeletal muscle is characterized by long lasting contractile responses and high resistance to fatigue. GO:1903231 mRNA binding involved in posttranscriptional gene silencing biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1903231 mRNA binding involved in quelling|mRNA binding involved in post-transcriptional gene silencing|mRNA binding involved in cosuppression|mRNA binding involved in PTGS Any mRNA binding that is involved in posttranscriptional gene silencing. GO:1903230 obsolete miRNA binding involved in posttranscriptional gene silencing biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1903230 microRNA binding involved in PTGS|microRNA binding involved in post-transcriptional gene silencing|microRNA binding involved in cosuppression|miRNA binding involved in PTGS|microRNA binding involved in quelling|miRNA binding involved in posttranscriptional gene silencing|miRNA binding involved in quelling|microRNA binding involved in posttranscriptional gene silencing|miRNA binding involved in post-transcriptional gene silencing|miRNA binding involved in cosuppression OBSOLETE. Any miRNA binding that is involved in posttranscriptional gene silencing. GO:0014724 regulation of twitch skeletal muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014724 Any process that modulates the frequency, rate or extent of twitch skeletal muscle contraction. GO:0014723 regulation of skeletal muscle contraction by modulation of calcium ion sensitivity of myofibril biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014723 regulation of calcium ion sensitivity of myofibril involved in skeletal muscle contraction Any process that modulates the frequency, rate or extent of skeletal muscle contraction by changing calcium ion binding affinity of the myofibril. UBERON:0011628 early premaxilla biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011628 future premaxilla GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014722 regulation of skeletal muscle contraction by calcium ion signalling Any process that modulates the frequency, rate or extent of skeletal muscle contraction by changing the calcium ion signals that trigger contraction. GO:0014721 twitch skeletal muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014721 A process in which force is generated within twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The twitch skeletal muscle responds to neurostimulations with a contraction followed by a relaxation. CHEBI:38484 ergoline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38484 GO:0048071 sex-specific pigmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048071 Establishment of a pattern of pigment in one sex that is not observed in the other sex. GO:0048070 regulation of developmental pigmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048070 regulation of pigmentation during development Any process that modulates the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism. CHEBI:38482 indole alkaloid fundamental parent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38482 CHEBI:38481 alkaloid ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38481 GO:0097002 mitochondrial inner boundary membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097002 NIF_Subcellular:sao18461326 inner bounding mitochondrial membrane The portion of the mitochondrial inner membrane that is not invaginated to form cristae. The inner boundary membrane lies parallel to the outer membrane. GO:0048079 regulation of cuticle pigmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048079 Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism. GO:0048078 positive regulation of compound eye pigmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048078 upregulation of eye pigmentation|up-regulation of eye pigmentation|stimulation of eye pigmentation|activation of eye pigmentation|positive regulation of eye pigmentation|up regulation of eye pigmentation Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the compound eye. GO:0097001 ceramide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097001 Interacting selectively and non-covalently with any ceramide, a class of lipids that is composed of sphingosine linked to a fatty acid. Ceramides are a major component of cell membranes. GO:0048077 negative regulation of compound eye pigmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048077 downregulation of eye pigmentation|down regulation of eye pigmentation|inhibition of eye pigmentation|down-regulation of eye pigmentation|negative regulation of eye pigmentation Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the compound eye. GO:0097004 adipokinetic hormone binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097004 AKH binding Interacting selectively and non-covalently with an adipokinetic hormone. Adipokinetic hormones (AKHs) are peptide hormones that are involved in the mobilization of sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis. GO:0048076 regulation of compound eye pigmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048076 Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the compound eye. GO:0097003 adipokinetic hormone receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097003 AKH receptor activity Combining with an adipokinetic hormone to initiate a change in cell activity. Adipokinetic hormones (AKHs) are protein or peptide hormones that are important for sugar and fat homeostasis in metazoa. In insects, they mobilize sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis. GO:0048075 positive regulation of eye pigmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048075 stimulation of eye pigmentation|up-regulation of eye pigmentation|activation of eye pigmentation|up regulation of eye pigmentation|upregulation of eye pigmentation Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism. GO:0048074 negative regulation of eye pigmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048074 down-regulation of eye pigmentation|downregulation of eye pigmentation|down regulation of eye pigmentation|inhibition of eye pigmentation Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism. GO:0048073 regulation of eye pigmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048073 Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism. GO:0048072 compound eye pigmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048072 Establishment of a pattern of pigment in the compound eye. GO:0014739 positive regulation of muscle hyperplasia biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014739 Any process that activates or increases the frequency, rate or extent of muscle hyperplasia. GO:0014738 regulation of muscle hyperplasia biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014738 Any process that modulates the frequency, rate or extent of muscle hyperplasia. GO:1903239 obsolete regulation of positive regulation of the force of heart contraction by chemical signal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903239 regulation of positive regulation of the force of heart muscle contraction by chemical signal|regulation of positive regulation of the force of heart contraction by chemical signal OBSOLETE. Any process that modulates the frequency, rate or extent of positive regulation of the force of heart contraction by chemical signal. GO:0014737 positive regulation of muscle atrophy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014737 Any process that activates or increases the frequency, rate or extent of muscle atrophy. GO:1903238 positive regulation of leukocyte tethering or rolling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903238 up regulation of leukocyte tethering or rolling|upregulation of leukocyte tethering or rolling|activation of leukocyte tethering or rolling|up-regulation of leukocyte tethering or rolling Any process that activates or increases the frequency, rate or extent of leukocyte tethering or rolling. GO:1903237 negative regulation of leukocyte tethering or rolling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903237 down-regulation of leukocyte tethering or rolling|downregulation of leukocyte tethering or rolling|down regulation of leukocyte tethering or rolling|inhibition of leukocyte tethering or rolling Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte tethering or rolling. GO:0014736 negative regulation of muscle atrophy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014736 Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle atrophy. CHEBI:133748 citrate anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133748 GO:1903236 regulation of leukocyte tethering or rolling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903236 Any process that modulates the frequency, rate or extent of leukocyte tethering or rolling. GO:1903235 positive regulation of calcium ion-dependent exocytosis of neurotransmitter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903235 up-regulation of calcium ion-dependent exocytosis of neurotransmitter|activation of calcium ion-dependent exocytosis of neurotransmitter|up regulation of calcium ion-dependent exocytosis of neurotransmitter|upregulation of calcium ion-dependent exocytosis of neurotransmitter Any process that activates or increases the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter. GO:1903234 negative regulation of calcium ion-dependent exocytosis of neurotransmitter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903234 down-regulation of calcium ion-dependent exocytosis of neurotransmitter|downregulation of calcium ion-dependent exocytosis of neurotransmitter|down regulation of calcium ion-dependent exocytosis of neurotransmitter|inhibition of calcium ion-dependent exocytosis of neurotransmitter Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter. GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903233 Any process that modulates the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter. GO:0014731 spectrin-associated cytoskeleton biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0014731 The part of the cytoskeleton composed of spectrin, protein 4.1 and ankyrin. Spectrin-associated cytoskeleton is associated with the plasma membrane. GO:1903243 negative regulation of cardiac muscle hypertrophy in response to stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903243 downregulation of cardiac muscle hypertrophy in response to stress|down regulation of cardiac muscle hypertrophy in response to stress|inhibition of cardiac muscle hypertrophy in response to stress|down-regulation of cardiac muscle hypertrophy in response to stress Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle hypertrophy in response to stress. GO:1903242 regulation of cardiac muscle hypertrophy in response to stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903242 Any process that modulates the frequency, rate or extent of cardiac muscle hypertrophy in response to stress. GO:0014730 skeletal muscle regeneration at neuromuscular junction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014730 The regrowth of muscle tissue to repair injured or damaged muscle fibers in the postnatal stage at the neuromuscular junction. Regeneration of neuromuscular junctions occurs in an orderly way and relies on communication between nerve and muscle. Skeletal myofibers regenerate after injury and form neuro-muscular junctions with motor axons similar to normal ones. Regenerating myofibers develop within the basal lamina sheaths (satellite cells) of original myofibers. GO:1903241 U2-type prespliceosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903241 major prespliceosome assembly|GT-AG prespliceosome formation|mammalian U2-type spliceosomal complex A assembly|yeast U2-type spliceosomal complex B formation|yeast U2-type spliceosomal complex B assembly|mammalian U2-type spliceosomal complex A formation|GT-AG prespliceosome assembly|U2-type prespliceosome formation|major prespliceosome formation The aggregation, arrangement and bonding together of a set of components to form an U2-type prespliceosome. CHEBI:133741 (E)-dodec-2-enal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133741 GO:1903240 obsolete negative regulation of positive regulation of the force of heart contraction by chemical signal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903240 down-regulation of positive regulation of the force of heart contraction by chemical signal|downregulation of positive regulation of the force of heart contraction by chemical signal|down regulation of positive regulation of the force of heart muscle contraction by chemical signal|down regulation of positive regulation of the force of heart contraction by chemical signal|downregulation of positive regulation of the force of heart muscle contraction by chemical signal|inhibition of positive regulation of the force of heart contraction by chemical signal|negative regulation of positive regulation of the force of heart contraction by chemical signal|down-regulation of positive regulation of the force of heart muscle contraction by chemical signal|negative regulation of positive regulation of the force of heart muscle contraction by chemical signal|inhibition of positive regulation of the force of heart muscle contraction by chemical signal OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of positive regulation of the force of heart contraction by chemical signal. GO:0014735 regulation of muscle atrophy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014735 Any process that modulates the frequency, rate or extent of muscle atrophy. UBERON:0035606 cartilage of external acoustic meatus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035606 cartilage of auditory canal|cartilago meatus acustici|external acoustic meatus cartilage|cartilage of acoustic meatus GO:0014734 skeletal muscle hypertrophy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014734 The enlargement or overgrowth of all or part of an organ due to an increase in size (not length) of individual muscle fibers without cell division. In the case of skeletal muscle cells this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils. GO:0014733 regulation of skeletal muscle adaptation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014733 regulation of skeletal muscle plasticity Any process in which skeletal muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities. UBERON:0035608 dura mater lymph vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035608 dural lymph vessel|dural lymph vasculature Any lymph vessel that is located in the dura mater of the brain. GO:0014732 skeletal muscle atrophy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014732 A process, occurring in skeletal muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse. GO:0048082 regulation of adult chitin-containing cuticle pigmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048082 Any process that modulates the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism. GO:0048081 positive regulation of cuticle pigmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048081 up regulation of cuticle pigmentation|upregulation of cuticle pigmentation|stimulation of cuticle pigmentation|up-regulation of cuticle pigmentation|activation of cuticle pigmentation Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism. GO:0097009 energy homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097009 negative regulation of energy homeostasis|positive regulation of energy homeostasis|regulation of energy homeostasis Any process involved in the balance between food intake (energy input) and energy expenditure. GO:0048080 negative regulation of cuticle pigmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048080 downregulation of cuticle pigmentation|down regulation of cuticle pigmentation|inhibition of cuticle pigmentation|down-regulation of cuticle pigmentation Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism. GO:0097006 regulation of plasma lipoprotein particle levels biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097006 plasma lipoprotein particle homeostasis Any process involved in the maintenance of internal levels of plasma lipoprotein particles within an organism. GO:0097005 adipokinetic hormone receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097005 AKH receptor binding Interacting selectively and non-covalently with an adipokinetic hormone receptor. Adipokinetic hormones (AKHs) are peptide hormones that are involved in the mobilization of sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis. CHEBI:38498 mitochondrial NADH:ubiquinone reductase inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38498 GO:0097008 (3E)-4,8-dimethyl-1,3,7-nonatriene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097008 MetaCyc:RXN-8619 (3E)-4,8-dimethylnona-1,3,7-triene synthase activity|DNMT synthase activity Catalysis of the reaction: (E)-nerolidol + NADPH + O2 = (3E)-4,8-dimethylnona-1,3,7-triene + NADP+ + 2 H2O. It is unknown whether this reaction proceeds by the direct release of the 4-carbon compound but-1-en-3-one, or whether the substrate is first degraded to C11-geranylacetone and then cleaved to produce (3E)-4,8-dimethylnona-1,3,7-triene (DMNT) and acetone. CHEBI:38497 respiratory-chain inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38497 GO:0097007 4,8,12-trimethyltrideca-1,3,7,11-tetraene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097007 MetaCyc:RXN-8620|RHEA:13545 TMTT synthase activity|4,8,12-trimethyl-1,3,7,11-tridecatetraene synthase activity Catalysis of the reaction: (EE)-geranyllinalool + NADPH + O2 = 4,8,12-trimethyl-1,3,7,11-tridecatetraene + NADP+ + 2 H2O. It is unknown whether this reaction proceeds by the direct release of the 4-carbon compound but-1-en-3-one, or whether the substrate is first degraded to C18-farnesylacetone and then cleaved to produce 4,8,12-trimethyl-1,3,7,11-tridecatetraene (TMTT) and acetone. CHEBI:38496 electron-transport chain inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38496 CHEBI:167098 N-(fatty acyl)-amine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_167098 GO:0048089 regulation of female pigmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048089 Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in females. CHEBI:167097 trihexosylceramide sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_167097 GO:0048088 regulation of male pigmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048088 Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in males. GO:0048087 positive regulation of developmental pigmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048087 up regulation of developmental pigmentation|upregulation of developmental pigmentation|stimulation of developmental pigmentation|up-regulation of developmental pigmentation|activation of developmental pigmentation Any process that increases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism. GO:0048086 negative regulation of developmental pigmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048086 down-regulation of developmental pigmentation|downregulation of developmental pigmentation|down regulation of developmental pigmentation|inhibition of pigmentation Any process that decreases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism. CHEBI:167094 medium-chain 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_167094 GO:0048085 adult chitin-containing cuticle pigmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048085 adult cuticle pigmentation Establishment of the adult pattern of pigmentation in the chitin-containing cuticle of an organism. An example of this is the adult cuticle pigmentation process in Drosophila melanogaster. GO:0048084 positive regulation of adult chitin-containing cuticle pigmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048084 up regulation of adult chitin-containing cuticle pigmentation|upregulation of adult chitin-containing cuticle pigmentation|stimulation of adult chitin-containing cuticle pigmentation|up-regulation of adult chitin-containing cuticle pigmentation|activation of adult chitin-containing cuticle pigmentation Any process that activates or increases the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism. GO:0048083 negative regulation of adult chitin-containing cuticle pigmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048083 downregulation of adult chitin-containing cuticle pigmentation|down regulation of adult chitin-containing cuticle pigmentation|inhibition of adult chitin-containing cuticle pigmentation|down-regulation of adult chitin-containing cuticle pigmentation Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism. CHEBI:167095 secondary fatty alcohol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_167095 GO:0014706 striated muscle tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014706 The process whose specific outcome is the progression of a striated muscle over time, from its formation to the mature structure. Striated muscle contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. Skeletal muscle myoblasts fuse to form myotubes and eventually multinucleated muscle fibers. The fusion of cardiac cells is very rare and can only form binucleate cells. GO:0014705 C zone biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0014705 A region of the A band in which myosin-binding protein C is located and that can be seen by electron microscopy. This is a functional zone that also includes myosin. GO:1903249 negative regulation of citrulline biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903249 negative regulation of citrulline biosynthesis|down-regulation of citrulline biosynthesis|down-regulation of citrulline biosynthetic process|negative regulation of citrulline formation|down-regulation of citrulline formation|downregulation of citrulline anabolism|down regulation of citrulline anabolism|downregulation of citrulline synthesis|inhibition of citrulline biosynthesis|inhibition of citrulline biosynthetic process|inhibition of citrulline anabolism|downregulation of citrulline formation|down regulation of citrulline synthesis|inhibition of citrulline synthesis|down regulation of citrulline formation|inhibition of citrulline formation|down regulation of citrulline biosynthetic process|down regulation of citrulline biosynthesis|downregulation of citrulline biosynthetic process|downregulation of citrulline biosynthesis|negative regulation of citrulline anabolism|down-regulation of citrulline anabolism|negative regulation of citrulline synthesis|down-regulation of citrulline synthesis Any process that stops, prevents or reduces the frequency, rate or extent of citrulline biosynthetic process. CHEBI:133716 N-acetyl-L-valinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133716 GO:0014704 intercalated disc biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0014704 Wikipedia:Intercalated_disc intercalated disk A complex cell-cell junction at which myofibrils terminate in cardiomyocytes; mediates mechanical and electrochemical integration between individual cardiomyocytes. The intercalated disc contains regions of tight mechanical attachment (fasciae adherentes and desmosomes) and electrical coupling (gap junctions) between adjacent cells. GO:1903248 regulation of citrulline biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903248 regulation of citrulline anabolism|regulation of citrulline synthesis|regulation of citrulline formation|regulation of citrulline biosynthesis Any process that modulates the frequency, rate or extent of citrulline biosynthetic process. GO:0014703 oscillatory muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014703 A process in which force is generated within oscillatory skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Oscillatory muscle contraction occurs in insect wing muscles and is characterized by asynchrony between action potential and contraction and by stretch activation. GO:1903247 obsolete positive regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903247 activation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|upregulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|up regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate|up-regulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|activation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|activation of adrenergic receptor signaling pathway involved in positive regulation of heart rate|upregulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|up regulation of activation of funny current by beta-adrenergic receptor signaling pathway|upregulation of If activation by beta-adrenergic receptor signaling pathway|up-regulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|positive regulation of activation of funny current by beta-adrenergic receptor signaling pathway|positive regulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|positive regulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|up regulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|up-regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate|up regulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|activation of activation of funny current by beta-adrenergic receptor signaling pathway|up-regulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|activation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|up regulation of If activation by beta-adrenergic receptor signaling pathway|positive regulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|up-regulation of activation of funny current by beta-adrenergic receptor signaling pathway|positive regulation of If activation by beta-adrenergic receptor signaling pathway|activation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|upregulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate|upregulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|up regulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|upregulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|activation of If activation by beta-adrenergic receptor signaling pathway|positive regulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|up regulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|upregulation of activation of funny current by beta-adrenergic receptor signaling pathway|up-regulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|up-regulation of If activation by beta-adrenergic receptor signaling pathway OBSOLETE. Any process that activates or increases the frequency, rate or extent of adrenergic receptor signaling pathway involved in positive regulation of heart rate. GO:1903246 obsolete negative regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903246 down regulation of activation of funny current by beta-adrenergic receptor signaling pathway|down regulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|inhibition of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|downregulation of activation of funny current by beta-adrenergic receptor signaling pathway|inhibition of If activation by beta-adrenergic receptor signaling pathway|down-regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate|negative regulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|down-regulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|down-regulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|negative regulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|inhibition of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|down regulation of If activation by beta-adrenergic receptor signaling pathway|inhibition of adrenergic receptor signaling pathway involved in positive regulation of heart rate|down-regulation of activation of funny current by beta-adrenergic receptor signaling pathway|negative regulation of activation of funny current by beta-adrenergic receptor signaling pathway|downregulation of If activation by beta-adrenergic receptor signaling pathway|downregulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|downregulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|negative regulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|down-regulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|down regulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|down regulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|negative regulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|down-regulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|inhibition of adrenergic receptor signalling pathway involved in positive regulation of heart rate|inhibition of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|negative regulation of If activation by beta-adrenergic receptor signaling pathway|down-regulation of If activation by beta-adrenergic receptor signaling pathway|down regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate|inhibition of activation of funny current by beta-adrenergic receptor signaling pathway|downregulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|downregulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|down regulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|downregulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of adrenergic receptor signaling pathway involved in positive regulation of heart rate. GO:0014709 positive regulation of somitomeric trunk muscle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014709 Any process that activates, maintains or increases the frequency, rate or extent of somitomeric trunk muscle development. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. GO:1903245 obsolete regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903245 regulation of activation of funny current by beta-adrenergic receptor signaling pathway|regulation of If activation by beta-adrenergic receptor signaling pathway|regulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|regulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|regulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|regulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate OBSOLETE. Any process that modulates the frequency, rate or extent of adrenergic receptor signaling pathway involved in positive regulation of heart rate. GO:0014708 regulation of somitomeric trunk muscle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014708 Any process that modulates the frequency, rate or extent of somitomeric trunk muscle development. GO:1903244 positive regulation of cardiac muscle hypertrophy in response to stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903244 upregulation of cardiac muscle hypertrophy in response to stress|activation of cardiac muscle hypertrophy in response to stress|up-regulation of cardiac muscle hypertrophy in response to stress|up regulation of cardiac muscle hypertrophy in response to stress Any process that activates or increases the frequency, rate or extent of cardiac muscle hypertrophy in response to stress. GO:0014707 branchiomeric skeletal muscle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014707 The process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. The branchiomeric muscle is derived from cranial mesoderm and controls facial expression, pharyngeal and laryngeal function, operating the jaw. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. Branchiomeric muscles of mammals correspond to the gill musculature of fish. CHEBI:133719 hydroxyoctanoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133719 GO:1903254 hercynylselenocysteine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903254 hercynylselenocysteine metabolism The chemical reactions and pathways involving hercynylselenocysteine. UBERON:0011602 gingiva of lower jaw biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011602 lower jaw gum|lower gum|lower jaw gingiva|lower gingiva|gum of lower jaw|mandibular gum|gum of mandible A gingiva that is part of a lower jaw region. GO:1903253 hercynylcysteine sulfoxide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903253 hercynylcysteine sulfoxide anabolism|hercynylcysteine sulfoxide synthesis|hercynylcysteine sulfoxide biosynthesis|hercynylcysteine sulfoxide formation The chemical reactions and pathways resulting in the formation of hercynylcysteine sulfoxide. GO:1903252 hercynylcysteine sulfoxide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903252 hercynylcysteine sulfoxide metabolism The chemical reactions and pathways involving hercynylcysteine sulfoxide. UBERON:0011601 gingiva of upper jaw biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011601 maxillary gum|upper gum|upper jaw gingiva|upper gingiva|gum of upper jaw|gum of maxilla A gingiva that is part of a upper jaw region. CHEBI:38468 indol-3-yl carboxylic acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38468 GO:1903251 multi-ciliated epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903251 multiciliate cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a multi-ciliated epithelial cell. CHEBI:38467 indolyl alcohol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38467 GO:1903250 positive regulation of citrulline biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903250 up-regulation of citrulline synthesis|activation of citrulline synthesis|up regulation of citrulline biosynthesis|up regulation of citrulline biosynthetic process|up-regulation of citrulline formation|activation of citrulline formation|activation of citrulline biosynthesis|positive regulation of citrulline biosynthesis|activation of citrulline biosynthetic process|positive regulation of citrulline anabolism|up regulation of citrulline anabolism|positive regulation of citrulline synthesis|up regulation of citrulline synthesis|positive regulation of citrulline formation|up-regulation of citrulline biosynthetic process|up-regulation of citrulline biosynthesis|up regulation of citrulline formation|upregulation of citrulline anabolism|upregulation of citrulline synthesis|upregulation of citrulline biosynthesis|upregulation of citrulline biosynthetic process|upregulation of citrulline formation|up-regulation of citrulline anabolism|activation of citrulline anabolism Any process that activates or increases the frequency, rate or extent of citrulline biosynthetic process. GO:0014702 free sarcoplasmic reticulum membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0014702 The part of the sarcoplasmic reticulum membrane that contains calcium pumps and is devoted to calcium uptake. The free sarcoplasmic reticulum membrane consists of the longitudinal sarcoplasmic reticulum membrane and the non-junctional region of the terminal cisterna membrane. GO:0014701 junctional sarcoplasmic reticulum membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0014701 The part of the sarcoplasmic reticulum membrane that contains calcium release channels, is devoted to calcium release and is juxtaposed to transverse tubule membrane. The junctional sarcoplasmic reticulum membrane consists of the junctional region of the terminal cisterna membrane. GO:0048093 positive regulation of male pigmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048093 up-regulation of male pigmentation|upregulation of male pigmentation|up regulation of male pigmentation|activation of male pigmentation|stimulation of male pigmentation Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in males. CHEBI:38462 EC 3.1.1.7 (acetylcholinesterase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38462 GO:0048092 negative regulation of male pigmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048092 inhibition of male pigmentation|down regulation of male pigmentation|downregulation of male pigmentation|down-regulation of male pigmentation Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in males. GO:0048091 positive regulation of female pigmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048091 up-regulation of female pigmentation|upregulation of female pigmentation|up regulation of female pigmentation|activation of female pigmentation|stimulation of female pigmentation Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in females. CHEBI:38460 methylindole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38460 GO:0048090 negative regulation of female pigmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048090 inhibition of female pigmentation|down regulation of female pigmentation|downregulation of female pigmentation|down-regulation of female pigmentation Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in females. CHEBI:38466 imidazolyl carboxylic acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38466 GO:0048099 anterior/posterior lineage restriction, imaginal disc biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048099 Formation and/or maintenance of a lineage boundary between anterior and posterior compartments that cells cannot cross, thus separating the populations of cells in each compartment. GO:0048098 antennal joint development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048098 The process whose specific outcome is the progression of the antennal joint over time, from its formation to the mature structure. The antennal joint is the joint between antennal segments. GO:0048097 long-term maintenance of gene activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048097 Any mechanism, at the level of transcription or post-transcription, maintaining gene activation in the long-term. GO:0048096 chromatin-mediated maintenance of transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048096 Maintenance of transcription by remodelling of chromatin into an 'open configuration'. Once established, this regulation is mitotically stable and is maintained over many cell divisions. It is also heritable. GO:0048095 female pigmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048095 Establishment of a pattern of pigment in females. GO:0048094 male pigmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048094 Establishment of a pattern of pigment in males. GO:0014717 regulation of satellite cell activation involved in skeletal muscle regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014717 Any process that modulates the frequency, rate or extent of satellite cell activation. The satellite cell activation is the process that initiates satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate. GO:0014716 skeletal muscle satellite stem cell asymmetric division involved in skeletal muscle regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014716 satellite cell asymmetric division involved in skeletal muscle regeneration Skeletal muscle satellite cell asymmetric division that occurs during a process in which damaged muscle tissue is being rebuilt. GO:0014715 myoblast fate commitment in trunk biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014715 The process taking place in the trunk whereby the developmental fate of a cell becomes restricted such that it will develop into a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. GO:1903259 exon-exon junction complex disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903259 EJC disassembly The disaggregation of an exon-exon junction complex into its constituent components. GO:0014714 myoblast fate commitment in head biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014714 The process, taking place in the head, whereby the developmental fate of a cell becomes restricted such that it will develop into a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. GO:1903258 sorbose import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903258 sorbose import into cell The process in which sorbose is transported from outside of a cell, across the plasma membrane and into the cytosol. GO:1903257 selenoneine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903257 L-selenoneine biosynthetic process|selenoneine anabolism|selenoneine synthesis|selenoneine biosynthesis|selenoneine formation The chemical reactions and pathways resulting in the formation of selenoneine. GO:1903256 selenoneine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903256 selenoneine metabolism|L-selenoneine metabolic process The chemical reactions and pathways involving selenoneine. GO:0014719 skeletal muscle satellite cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014719 The change of a skeletal muscle satellite cell from a mitotically quiescent to a mitotically active state following exposure to some activating factor such as a cellular or soluble ligand. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage. GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014718 Any process that activates, maintains or increases the frequency, rate or extent of activation of satellite cell involved in skeletal muscle regeneration. The activation of satellite cell is the process that initiates satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate. GO:1903255 hercynylselenocysteine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903255 hercynylselenocysteine synthesis|hercynylselenocysteine formation|hercynylselenocysteine biosynthesis|hercynylselenocysteine anabolism The chemical reactions and pathways resulting in the formation of hercynylselenocysteine. GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903265 positive regulation of tumor necrosis factor alpha-mediated signaling pathway|upregulation of TNF-alpha-mediated signaling pathway|up regulation of tumor necrosis factor alpha-mediated signaling pathway|up regulation of adipocytokine signaling pathway|up-regulation of tumor necrosis factor-mediated signalling pathway|positive regulation of adipocytokine signaling pathway|up regulation of tumor necrosis factor-mediated signaling pathway|up-regulation of TNF-alpha-mediated signaling pathway|activation of adipocytokine signaling pathway|upregulation of tumor necrosis factor alpha-mediated signaling pathway|upregulation of tumor necrosis factor-mediated signalling pathway|activation of TNF-alpha-mediated signaling pathway|up-regulation of adipocytokine signaling pathway|upregulation of tumor necrosis factor-mediated signaling pathway|positive regulation of TNF-alpha-mediated signaling pathway|up-regulation of tumor necrosis factor alpha-mediated signaling pathway|up regulation of TNF-alpha-mediated signaling pathway|up regulation of tumor necrosis factor-mediated signalling pathway|upregulation of adipocytokine signaling pathway|positive regulation of tumor necrosis factor-mediated signalling pathway|activation of tumor necrosis factor alpha-mediated signaling pathway|activation of tumor necrosis factor-mediated signalling pathway|up-regulation of tumor necrosis factor-mediated signaling pathway|activation of tumor necrosis factor-mediated signaling pathway Any process that activates or increases the frequency, rate or extent of tumor necrosis factor-mediated signaling pathway. GO:1903264 nitrate reductase activity involved in anaerobic electron transport chain biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1903264 respiratory nitrate reductase activity involved in anaerobic electron transport chain|nitrite:acceptor oxidoreductase involved in anaerobic electron transport chain|nitrate reductase (acceptor) involved in anaerobic electron transport chain|nitrite:(acceptor) oxidoreductase involved in anaerobic electron transport chain Any nitrate reductase activity that is involved in anaerobic electron transport chain. GO:1903263 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1903263 GO:1903262 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1903262 GO:0014713 negative regulation of branchiomeric skeletal muscle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014713 Any process that stops, prevents, or reduces the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. GO:1903261 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1903261 GO:1903260 protein localization to mating projection tip biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903260 protein localization in mating projection tip|protein localization to conjugation tube tip|protein localisation in mating projection tip|protein localization to shmoo tip|protein localisation to mating projection tip A process in which a protein is transported to, or maintained in, a location within a mating projection tip. CHEBI:133720 glycochenodeoxycholic acid sulfate anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133720 GO:0014712 positive regulation of branchiomeric skeletal muscle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014712 Any process that activates, maintains or increases the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. CHEBI:133723 naphthalene-1,2,4,8-tetrol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133723 GO:0014711 regulation of branchiomeric skeletal muscle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014711 Any process that modulates the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. GO:0014710 negative regulation of somitomeric trunk muscle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014710 Any process that stops, prevents, or reduces the frequency, rate or extent of somitomeric trunk muscle development. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. CHEBI:38472 acetonitrile biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38472 GO:0097035 regulation of membrane lipid distribution biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097035 Any process that modulates the proportions or spatial arrangement of lipids in a cellular membrane. GO:0097034 obsolete mitochondrial respiratory chain complex IV biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097034 mitochondrial cytochrome c oxidase complex biogenesis OBSOLETE. The biogenesis of a mitochondrial respiratory chain complex IV (also known as cytochrome c oxidase complex), a protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Includes the synthesis of constituent proteins and their aggregation, arrangement and bonding together. GO:0097037 heme export biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097037 The directed movement of heme out of a cell or organelle. GO:0097036 regulation of plasma membrane sterol distribution biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097036 Any process that modulates the proportions or spatial arrangement of sterols in the plasma membrane. GO:0097031 obsolete mitochondrial respiratory chain complex I biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097031 OBSOLETE. The biogenesis of a mitochondrial respiratory chain complex I, a protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Includes the synthesis of constituent proteins and their aggregation, arrangement and bonding together. GO:0097030 CENP-A containing nucleosome binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097030 centromeric nucleosome binding|centromere-specific nucleosome binding Interacting selectively and non-covalently with a centromere-specific nucleosome, a form of nucleosome located only at the centromere, in which the histone H3 is replaced by the variant form CENP-A (sometimes known as CenH3). GO:0097033 obsolete mitochondrial respiratory chain complex III biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097033 mitochondrial cytochrome bc(1) complex biogenesis OBSOLETE. The biogenesis of a mitochondrial respiratory chain complex III (also known as cytochrome bc(1) complex or ubiquinol-cytochrome c reductase), a protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Includes the synthesis of constituent proteins and their aggregation, arrangement and bonding together. NCBITaxon:2157 Archaea organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_2157 Monera|archaea|prokaryotes|Procaryotae|Metabacteria|Mendosicutes|prokaryote|Prokaryotae|Prokaryota|Archaebacteria GO:0097032 obsolete mitochondrial respiratory chain complex II biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097032 OBSOLETE. The biogenesis of a mitochondrial respiratory chain complex II, a protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Includes the synthesis of constituent proteins and their aggregation, arrangement and bonding together. UBERON:0011676 subdivision of organism along main body axis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011676 axial subdivision of organism|main body segment|body segment A major subdivision of an organism that divides an organism along its main body axis (typically anterio-posterior axis). In vertebrates, this is based on the vertebral column. GO:1903269 ornithine carbamoyltransferase inhibitor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1903269 ornithine carbamoyltransferase arginase complex|OTC-ARGI complex A protein complex which is capable of ornithine carbamoyltransferase inhibitor activity. GO:1903268 positive regulation of ornithine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903268 positive regulation of ornithine catabolism|activation of ornithine degradation|positive regulation of ornithine degradation|up regulation of ornithine catabolism|up regulation of ornithine breakdown|activation of ornithine breakdown|positive regulation of ornithine breakdown|up regulation of ornithine catabolic process|activation of ornithine catabolic process|up-regulation of ornithine degradation|upregulation of ornithine catabolism|up-regulation of ornithine breakdown|activation of ornithine catabolism|up-regulation of ornithine catabolism|up-regulation of ornithine catabolic process|upregulation of ornithine degradation|upregulation of ornithine breakdown|upregulation of ornithine catabolic process|up regulation of ornithine degradation Any process that activates or increases the frequency, rate or extent of ornithine catabolic process. GO:1903267 negative regulation of ornithine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903267 down regulation of ornithine catabolic process|downregulation of ornithine breakdown|downregulation of ornithine catabolism|negative regulation of ornithine degradation|downregulation of ornithine catabolic process|down-regulation of ornithine degradation|down regulation of ornithine catabolism|negative regulation of ornithine breakdown|down-regulation of ornithine breakdown|inhibition of ornithine catabolism|inhibition of ornithine degradation|down-regulation of ornithine catabolic process|inhibition of ornithine breakdown|inhibition of ornithine catabolic process|down regulation of ornithine degradation|downregulation of ornithine degradation|down-regulation of ornithine catabolism|negative regulation of ornithine catabolism|down regulation of ornithine breakdown Any process that stops, prevents or reduces the frequency, rate or extent of ornithine catabolic process. GO:1903266 regulation of ornithine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903266 regulation of ornithine catabolism|regulation of ornithine degradation|regulation of ornithine breakdown Any process that modulates the frequency, rate or extent of ornithine catabolic process. GO:1903276 regulation of sodium ion export across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903276 regulation of sodium ion export from cell|regulation of sodium export|regulation of sodium ion export Any process that modulates the frequency, rate or extent of sodium ion export across the plasma membrane. CHEBI:38448 trichloromuconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38448 GO:1903275 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1903275 GO:1903274 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1903274 CHEBI:38445 chromenone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38445 GO:1903273 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1903273 GO:1903272 positive regulation of cytoplasmic translational elongation through polyproline stretches biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903272 up-regulation of cytoplasmic translational elongation through polyproline stretches|activation of cytoplasmic translational elongation through polyproline stretches|up regulation of cytoplasmic translational elongation through polyproline stretches|upregulation of cytoplasmic translational elongation through polyproline stretches Any process that activates or increases the frequency, rate or extent of cytoplasmic translational elongation through polyproline stretches. GO:1903271 negative regulation of cytoplasmic translational elongation through polyproline stretches biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903271 down-regulation of cytoplasmic translational elongation through polyproline stretches|downregulation of cytoplasmic translational elongation through polyproline stretches|down regulation of cytoplasmic translational elongation through polyproline stretches|inhibition of cytoplasmic translational elongation through polyproline stretches Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational elongation through polyproline stretches. GO:1903270 regulation of cytoplasmic translational elongation through polyproline stretches biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903270 Any process that modulates the frequency, rate or extent of cytoplasmic translational elongation through polyproline stretches. GO:0097039 protein linear polyubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097039 M1 linkage A protein ubiquitination process in which a linear polymer of ubiquitin, formed by the amino-terminal methionine (M1) of one ubiquitin molecule and by the carboxy-terminal glycine (G76) of the next, is added to a protein. CHEBI:38444 2-benzopyran biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38444 GO:0097038 perinuclear endoplasmic reticulum biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097038 perinuclear ER The portion of endoplasmic reticulum, the intracellular network of tubules and cisternae, that occurs near the nucleus. The lumen of the perinuclear endoplasmic reticulum is contiguous with the nuclear envelope lumen (also called perinuclear space), the region between the inner and outer nuclear membranes. CHEBI:38443 1-benzopyran biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38443 CHEBI:7027 2-amino-3-O-[(R)-1-carboxyethyl]-2-deoxy-D-glucopyranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_7027 GO:0097046 replication fork progression beyond termination site biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097046 Regulation of DNA replication by a mechanism that allows a DNA replication fork to progress beyond a termination site, which is a region containing fork pausing elements that influence the progression and merging of DNA replication forks. GO:0097045 phosphatidylserine exposure on blood platelet biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097045 A phospholipid scrambling process that results in the appearance of phosphatidylserine on the surface of activated blood platelets, and triggers the clotting system. GO:0097048 dendritic cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097048 dendritic cell apoptosis Any apoptotic process in a dendritic cell, a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. GO:0097047 DNA replication termination region biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097047 TER A chromosomal region that contains fork pausing elements influencing the progression and merging of DNA replication forks. GO:0097042 extrinsic component of fungal-type vacuolar membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097042 extrinsic to fungal-type vacuolar membrane The component of a fungal-type vacuolar membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:0097041 phenolic phthiocerol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097041 phenolphthiocerol biosynthesis|phenolic phthiocerol anabolism|phenolic phthiocerol synthesis|phenolic phthiocerol formation|phenolic phthiocerol biosynthesis The chemical reactions and pathways resulting in the formation of phenolic phthiocerol, a phthiocerol derivative having a 4-hydroxyphenyl substituent at the 29-position. GO:0097044 histone H3-K56 acetylation in response to DNA damage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097044 The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 56 of the histone as a result of the detection of DNA damage within a cell. GO:0097043 histone H3-K56 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097043 The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 56 of the histone. GO:0097040 phthiocerol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097040 phthiocerol anabolism|phthiocerol biosynthesis|phthiocerol synthesis|phthiocerol formation The chemical reactions and pathways resulting in the formation of phthiocerol, a lipid-based 1,3-glycol consisting of (3S,4R)-3-methoxy-4-methylnonacosane having (9R)- and (11S)-hydroxy substituents. GO:1903279 regulation of calcium:sodium antiporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903279 regulation of sodium:calcium exchange|regulation of mitochondrial sodium/calcium ion exchange|regulation of sodium/calcium exchanger Any process that modulates the frequency, rate or extent of calcium:sodium antiporter activity. GO:1903278 positive regulation of sodium ion export across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903278 up-regulation of sodium ion export|upregulation of sodium export|up-regulation of sodium ion export from cell|positive regulation of sodium ion export|activation of sodium export|positive regulation of sodium ion export from cell|upregulation of sodium ion export|up regulation of sodium export|upregulation of sodium ion export from cell|positive regulation of sodium export|activation of sodium ion export|up regulation of sodium ion export|up regulation of sodium ion export from cell|up-regulation of sodium export|activation of sodium ion export from cell Any process that activates or increases the frequency, rate or extent of sodium ion export across the plasma membrane. GO:1903277 negative regulation of sodium ion export across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903277 inhibition of sodium ion export from cell|down regulation of sodium export|downregulation of sodium export|negative regulation of sodium ion export|down regulation of sodium ion export|negative regulation of sodium ion export from cell|down regulation of sodium ion export from cell|downregulation of sodium ion export|negative regulation of sodium export|down-regulation of sodium export|inhibition of sodium export|downregulation of sodium ion export from cell|down-regulation of sodium ion export|inhibition of sodium ion export|down-regulation of sodium ion export from cell Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion export across the plasma membrane. GO:1903287 negative regulation of potassium ion import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903287 down regulation of potassium import|inhibition of potassium ion uptake|downregulation of potassium ion import|downregulation of potassium ion uptake|down regulation of potassium ion import|down regulation of potassium ion uptake|negative regulation of potassium ion import|negative regulation of potassium import|down-regulation of potassium import|inhibition of potassium import|down-regulation of potassium ion import|downregulation of potassium import|down-regulation of potassium ion uptake|negative regulation of potassium ion uptake|inhibition of potassium ion import Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion import across the plasma membrane. CHEBI:38459 oxindoles biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38459 CHEBI:14469 isomethyleugenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_14469 GO:1903286 regulation of potassium ion import biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903286 regulation of potassium import|regulation of potassium ion uptake Any process that modulates the frequency, rate or extent of potassium ion import. GO:1903285 positive regulation of hydrogen peroxide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903285 activation of detoxification of hydrogen peroxide|up regulation of hydrogen peroxide removal|up-regulation of H2O2 scavenging|upregulation of hydrogen peroxide catabolic process|activation of detoxification of H2O2|positive regulation of hydrogen peroxide removal|up regulation of hydrogen peroxide degradation|activation of hydrogen peroxide degradation|positive regulation of hydrogen peroxide degradation|activation of hydrogen peroxide catabolism|up-regulation of hydrogen peroxide catabolism|up-regulation of detoxification of hydrogen peroxide|up-regulation of H2O2 catabolic process|activation of H2O2 catabolic process|upregulation of hydrogen peroxide scavenging|positive regulation of detoxification of H2O2|up regulation of hydrogen peroxide breakdown|activation of hydrogen peroxide removal|activation of hydrogen peroxide breakdown|up regulation of detoxification of H2O2|positive regulation of hydrogen peroxide breakdown|upregulation of H2O2 scavenging|up regulation of hydrogen peroxide catabolic process|activation of hydrogen peroxide catabolic process|upregulation of detoxification of hydrogen peroxide|up-regulation of hydrogen peroxide removal|up-regulation of hydrogen peroxide scavenging|up-regulation of hydrogen peroxide degradation|positive regulation of hydrogen peroxide catabolism|positive regulation of H2O2 catabolic process|up regulation of hydrogen peroxide catabolism|upregulation of detoxification of H2O2|up regulation of H2O2 catabolic process|activation of hydrogen peroxide scavenging|up regulation of H2O2 scavenging|up-regulation of hydrogen peroxide breakdown|upregulation of hydrogen peroxide removal|positive regulation of H2O2 scavenging|up regulation of detoxification of hydrogen peroxide|upregulation of hydrogen peroxide degradation|up-regulation of hydrogen peroxide catabolic process|positive regulation of detoxification of hydrogen peroxide|positive regulation of hydrogen peroxide scavenging|upregulation of hydrogen peroxide catabolism|activation of H2O2 scavenging|up-regulation of detoxification of H2O2|up regulation of hydrogen peroxide scavenging|upregulation of H2O2 catabolic process|upregulation of hydrogen peroxide breakdown Any process that activates or increases the frequency, rate or extent of hydrogen peroxide catabolic process. GO:1903284 positive regulation of glutathione peroxidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903284 up-regulation of GSH peroxidase activity|up regulation of selenium-glutathione peroxidase activity|upregulation of glutathione:hydrogen-peroxide oxidoreductase activity|up regulation of glutathione peroxidase activity|up-regulation of non-selenium glutathione peroxidase activity|up regulation of reduced glutathione peroxidase activity|activation of glutathione peroxidase activity|positive regulation of reduced glutathione peroxidase activity|activation of reduced glutathione peroxidase activity|activation of non-selenium glutathione peroxidase activity|upregulation of GSH peroxidase activity|upregulation of selenium-glutathione peroxidase activity|up regulation of glutathione:hydrogen-peroxide oxidoreductase activity|positive regulation of non-selenium glutathione peroxidase activity|positive regulation of glutathione:hydrogen-peroxide oxidoreductase activity|activation of glutathione:hydrogen-peroxide oxidoreductase activity|up-regulation of glutathione peroxidase activity|up regulation of non-selenium glutathione peroxidase activity|up-regulation of reduced glutathione peroxidase activity|up-regulation of selenium-glutathione peroxidase activity|up regulation of GSH peroxidase activity|activation of selenium-glutathione peroxidase activity|positive regulation of GSH peroxidase activity|activation of GSH peroxidase activity|upregulation of glutathione peroxidase activity|enhancement of GPX activity|upregulation of non-selenium glutathione peroxidase activity|up-regulation of glutathione:hydrogen-peroxide oxidoreductase activity|upregulation of reduced glutathione peroxidase activity|positive regulation of selenium-glutathione peroxidase activity Any process that activates or increases the frequency, rate or extent of glutathione peroxidase activity. GO:1903283 negative regulation of glutathione peroxidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903283 inhibition of GSH peroxidase activity|downregulation of reduced glutathione peroxidase activity|downregulation of selenium-glutathione peroxidase activity|down regulation of glutathione:hydrogen-peroxide oxidoreductase activity|down regulation of selenium-glutathione peroxidase activity|negative regulation of non-selenium glutathione peroxidase activity|down-regulation of glutathione peroxidase activity|down-regulation of non-selenium glutathione peroxidase activity|inhibition of selenium-glutathione peroxidase activity|downregulation of glutathione:hydrogen-peroxide oxidoreductase activity|negative regulation of reduced glutathione peroxidase activity|down-regulation of reduced glutathione peroxidase activity|down regulation of GSH peroxidase activity|inhibition of glutathione peroxidase activity|inhibition of reduced glutathione peroxidase activity|downregulation of GSH peroxidase activity|downregulation of non-selenium glutathione peroxidase activity|negative regulation of glutathione:hydrogen-peroxide oxidoreductase activity|down-regulation of glutathione:hydrogen-peroxide oxidoreductase activity|down regulation of non-selenium glutathione peroxidase activity|inhibition of glutathione:hydrogen-peroxide oxidoreductase activity|down-regulation of GSH peroxidase activity|negative regulation of GSH peroxidase activity|negative regulation of selenium-glutathione peroxidase activity|down-regulation of selenium-glutathione peroxidase activity|down regulation of glutathione peroxidase activity|inhibition of non-selenium glutathione peroxidase activity|down regulation of reduced glutathione peroxidase activity|downregulation of glutathione peroxidase activity Any process that stops, prevents or reduces the frequency, rate or extent of glutathione peroxidase activity. GO:1903282 regulation of glutathione peroxidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903282 regulation of selenium-glutathione peroxidase activity|regulation of glutathione:hydrogen-peroxide oxidoreductase activity|regulation of GSH peroxidase activity|regulation of non-selenium glutathione peroxidase activity|regulation of reduced glutathione peroxidase activity Any process that modulates the frequency, rate or extent of glutathione peroxidase activity. GO:1903281 positive regulation of calcium:sodium antiporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903281 upregulation of calcium:sodium antiporter activity|activation of sodium:calcium exchange|upregulation of sodium/calcium exchanger|up regulation of mitochondrial sodium/calcium ion exchange|positive regulation of mitochondrial sodium/calcium ion exchange|up-regulation of sodium:calcium exchange|activation of mitochondrial sodium/calcium ion exchange|up-regulation of calcium:sodium antiporter activity|activation of calcium:sodium antiporter activity|up-regulation of sodium/calcium exchanger|activation of sodium/calcium exchanger|up-regulation of mitochondrial sodium/calcium ion exchange|upregulation of sodium:calcium exchange|positive regulation of sodium/calcium exchanger|up regulation of calcium:sodium antiporter activity|upregulation of mitochondrial sodium/calcium ion exchange|up regulation of sodium/calcium exchanger|up regulation of sodium:calcium exchange|positive regulation of sodium:calcium exchange Any process that activates or increases the frequency, rate or extent of calcium:sodium antiporter activity. GO:1903280 negative regulation of calcium:sodium antiporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903280 negative regulation of mitochondrial sodium/calcium ion exchange|down-regulation of mitochondrial sodium/calcium ion exchange|inhibition of sodium:calcium exchange|down-regulation of calcium:sodium antiporter activity|negative regulation of sodium/calcium exchanger|down-regulation of sodium/calcium exchanger|down regulation of sodium:calcium exchange|inhibition of mitochondrial sodium/calcium ion exchange|downregulation of sodium:calcium exchange|downregulation of calcium:sodium antiporter activity|down regulation of mitochondrial sodium/calcium ion exchange|downregulation of sodium/calcium exchanger|down regulation of calcium:sodium antiporter activity|downregulation of mitochondrial sodium/calcium ion exchange|down regulation of sodium/calcium exchanger|down-regulation of sodium:calcium exchange|negative regulation of sodium:calcium exchange|inhibition of calcium:sodium antiporter activity|inhibition of sodium/calcium exchanger Any process that stops, prevents or reduces the frequency, rate or extent of calcium:sodium antiporter activity. GO:0097049 motor neuron apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097049 motor neuron apoptosis|motoneuron apoptosis Any apoptotic process in a motor neuron, an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement. GO:0097013 phagocytic vesicle lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097013 The volume enclosed by the membrane of a phagocytic vesicle. GO:0097012 response to granulocyte macrophage colony-stimulating factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097012 response to granulocyte macrophage colony-stimulating factor stimulus|response to GM-CSF Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte macrophage colony-stimulating factor stimulus. GO:0097015 obsolete bacterial-type flagellar cytoplasm biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097015 bacterial-type flagellum cytoplasm OBSOLETE. All of the contents of a bacterial-type flagellum, excluding the plasma membrane surrounding the flagellum. GO:0097014 ciliary plasm biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097014 microtubule-based flagellar cytoplasm|microtubule-based flagellar matrix|cilium cytoplasm|microtubule-based flagellum matrix|cilium plasm|cilial cytoplasm|microtubule-based flagellum cytoplasm|ciliary cytoplasm All of the contents of a cilium, excluding the plasma membrane surrounding the cilium. GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097011 cellular response to GM-CSF stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte macrophage colony-stimulating factor stimulus. GO:0097010 eukaryotic translation initiation factor 4F complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097010 eIF4F assembly|eIF-4F assembly The aggregation, arrangement and bonding together of a set of components to form the eukaryotic translation initiation factor 4F complex. GO:1903289 obsolete regulation of ATP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903289 regulation of ATP degradation|regulation of ATP breakdown|regulation of ATP catabolism|regulation of ATP hydrolysis OBSOLETE. Any process that modulates the frequency, rate or extent of ATP catabolic process. UBERON:2001950 inter-premaxillary joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_2001950 Joint that articulates the left and right premaxillary bones. Inter-premaxillary joint is unpaired. GO:1903288 positive regulation of potassium ion import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903288 upregulation of potassium ion import|up-regulation of potassium import|activation of potassium import|upregulation of potassium ion uptake|up-regulation of potassium ion import|activation of potassium ion import|up-regulation of potassium ion uptake|positive regulation of potassium import|activation of potassium ion uptake|up regulation of potassium import|positive regulation of potassium ion import|up regulation of potassium ion import|positive regulation of potassium ion uptake|upregulation of potassium import|up regulation of potassium ion uptake Any process that activates or increases the frequency, rate or extent of potassium ion import across the plasma membrane. GO:1903298 negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903298 protection against hypoxia-induced apoptosis|down regulation of intrinsic apoptotic signaling pathway in response to hypoxia|inhibition of intrinsic apoptotic signaling pathway in response to hypoxia|negative regulation of hypoxic stress-induced intrinsic apoptotic signaling pathway|down-regulation of intrinsic apoptotic signaling pathway in response to hypoxia|negative regulation of intrinsic apoptotic signaling pathway in response to hypoxia|negative regulation of hypoxia-induced apoptosis|downregulation of intrinsic apoptotic signaling pathway in response to hypoxia Any process that stops, prevents or reduces the frequency, rate or extent of hypoxia-induced intrinsic apoptotic signaling pathway. CHEBI:38426 (2E,4Z)-5-carboxy-2,4,5-trichloropenta-2,4-dienoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38426 GO:1903297 regulation of hypoxia-induced intrinsic apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903297 regulation of intrinsic apoptotic signaling pathway in response to hypoxia|regulation of hypoxia-induced apoptosis|regulation of hypoxic stress-induced intrinsic apoptotic signaling pathway Any process that modulates the frequency, rate or extent of hypoxia-induced intrinsic apoptotic signaling pathway. CHEBI:38425 2,5-dichloromuconate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38425 GO:1903296 positive regulation of glutamate secretion, neurotransmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903296 upregulation of glutamate secretion, neurotransmission|up-regulation of glutamate secretion, neurotransmission|activation of glutamate secretion, neurotransmission|up regulation of glutamate secretion, neurotransmission Any process that activates or increases the frequency, rate or extent of glutamate secretion, where glutamate acts as a neurotransmitter. CHEBI:38424 dichloromuconate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38424 GO:1903295 negative regulation of glutamate secretion, neurotransmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903295 down regulation of glutamate secretion, neurotransmission|inhibition of glutamate secretion, neurotransmission|down-regulation of glutamate secretion, neurotransmission|downregulation of glutamate secretion, neurotransmission Any process that stops, prevents or reduces the frequency, rate or extent of glutamate secretion, neurotransmission. GO:1903294 regulation of glutamate secretion, neurotransmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903294 Any process that modulates the frequency, rate or extent of glutamate secretion, neurotransmission. GO:1903293 phosphatase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1903293 A protein complex which is capable of phosphatase activity. CHEBI:38429 monochloromuconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38429 GO:1903292 protein localization to Golgi membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903292 protein localization in Golgi membrane|protein localisation to Golgi membrane|protein localisation in Golgi membrane A process in which a protein is transported to, or maintained in, a location within a Golgi membrane. CHEBI:38428 3-chloromuconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38428 GO:1903291 obsolete positive regulation of ATP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903291 up regulation of ATP catabolic process|positive regulation of ATP hydrolysis|activation of ATP catabolic process|up regulation of ATP hydrolysis|upregulation of ATP catabolism|up-regulation of ATP degradation|up-regulation of ATP breakdown|up-regulation of ATP catabolism|activation of ATP catabolism|upregulation of ATP hydrolysis|up-regulation of ATP catabolic process|upregulation of ATP degradation|upregulation of ATP breakdown|up-regulation of ATP hydrolysis|upregulation of ATP catabolic process|positive regulation of ATP catabolism|up regulation of ATP degradation|up regulation of ATP catabolism|positive regulation of ATP degradation|activation of ATP degradation|activation of ATP hydrolysis|up regulation of ATP breakdown|activation of ATP breakdown|positive regulation of ATP breakdown OBSOLETE. Any process that activates or increases the frequency, rate or extent of ATP catabolic process. UBERON:0011648 jaw muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011648 mandibular muscles|mandibular muscle CHEBI:38427 2,3,5-trichloro-cis,cis-muconate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38427 GO:1903290 obsolete negative regulation of ATP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903290 inhibition of ATP catabolism|down-regulation of ATP breakdown|negative regulation of ATP breakdown|inhibition of ATP degradation|downregulation of ATP hydrolysis|down-regulation of ATP catabolic process|down regulation of ATP hydrolysis|inhibition of ATP breakdown|inhibition of ATP catabolic process|down regulation of ATP degradation|inhibition of ATP hydrolysis|down-regulation of ATP catabolism|negative regulation of ATP catabolism|downregulation of ATP degradation|down regulation of ATP breakdown|down regulation of ATP catabolic process|downregulation of ATP breakdown|downregulation of ATP catabolism|negative regulation of ATP hydrolysis|down-regulation of ATP hydrolysis|down-regulation of ATP degradation|negative regulation of ATP degradation|downregulation of ATP catabolic process|down regulation of ATP catabolism OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of ATP catabolic process. GO:0097017 renal protein absorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097017 A renal system process in which proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686). CHEBI:38422 dichloromuconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38422 GO:0097016 L27 domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097016 Interacting selectively and non-covalently with a L27 domain of a protein. L27 is composed of conserved negatively charged amino acids and a conserved aromatic amino acid. L27 domains can assemble proteins involved in signaling and establishment and maintenance of cell polarity into complexes by interacting in a heterodimeric manner. CHEBI:38421 2,5-dichloromuconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38421 GO:0097019 neurotransmitter receptor catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097019 neurotransmitter receptor degradation|neurotransmitter receptor catabolism|neurotransmitter receptor breakdown The chemical reactions and pathways resulting in the breakdown of neurotransmitter receptors. GO:0097018 renal albumin absorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097018 A renal system process in which albumin is taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. GO:0097024 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0097024 GO:0097023 fructose 6-phosphate aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097023 RHEA:28002 Catalysis of the reaction: D-fructose-6-phosphate = dihydroxyacetone + D-glyceraldehyde-3-phosphate. GO:0097026 dendritic cell dendrite assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097026 dendritic extension Formation of dendrites, branched cellular projections (or cytoplasmic extension) that are extended from the surface of a dendritic immune cell, and which enable the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells. GO:0097025 MPP7-DLG1-LIN7 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097025 A heterotrimeric protein complex formed by the association of MMP7, DLG1 and either LIN7A or LIN7C; regulates the stability and localization of DLG1 to cell junctions. GO:0097020 COPII receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097020 Binding specifically to a substance (cargo) to deliver it to a COPII transport vesicle. Cargo receptors span a membrane (either the plasma membrane or a vesicle membrane), binding simultaneously to cargo molecules and coat adaptors, to efficiently recruit soluble proteins to nascent vesicles. GO:0097022 lymphocyte migration into lymph node biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097022 lymphocyte homing The movement of a lymphocyte within the lymphatic system into a lymph node, and its subsequent positioning within defined functional compartments such as sites of cell activation by antigen. GO:0097021 lymphocyte migration into lymphoid organs biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097021 lymphocyte homing The movement of a lymphocyte within the lymphatic system into lymphoid organs such as lymph nodes, spleen or Peyer's patches, and its subsequent positioning within defined functional compartments such as sites of cell activation by antigen. UBERON:0011642 oral epithelium from ectoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011642 An epithelium that develops_from a ectoderm and is part of a oral epithelium. GO:1903299 regulation of hexokinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903299 regulation of hexokinase type IV (glucokinase) activity|regulation of hexokinase type II activity|regulation of hexokinase type I activity|regulation of hexokinase type III activity|regulation of glucose ATP phosphotransferase activity|regulation of hexokinase type IV|regulation of hexokinase (phosphorylating)|regulation of ATP-dependent hexokinase activity|regulation of hexokinase type IV glucokinase activity|regulation of hexokinase D|regulation of ATP:D-hexose 6-phosphotransferase activity Any process that modulates the frequency, rate or extent of hexokinase activity. CHEBI:38436 muconic semialdehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38436 UBERON:0011634 ectopterygoid bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011634 ectopterygoids|ectopterygoid A palatal bone which -- like many palatal bones -- may originally have developed as a dermal bone replacing part of the palatoquadrate, the primitive upper jaw. Like the palatine (also called dermopalatine), the ectopterygoid replaces the middle part of the autopalatine. It may be serially homologous with the palatine(s), but is somewhat specialized, being the last (most posterior in palatal view) of the series and bordering the fossa for the jaw muscles. In a typical tetrapod it abuts the palatine anteriorly, the maxilla laterally, the pterygoid or the fossa mandubuaris medially, and the fossa posteriorly CHEBI:38434 2-chloromuconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38434 GO:0097028 dendritic cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097028 The process in which a precursor cell type acquires the specialized features of a dendritic cell. A dendritic cell is a leukocyte of dendritic lineage specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. GO:0097027 ubiquitin-protein transferase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097027 Increases the activity of a ubiquitin-protein transferase, an enzyme that catalyzes the covalent attachment of ubiquitin to lysine in a substrate protein. GO:0097029 mature conventional dendritic cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097029 The process in which antigen-activated dendritic cells acquire the specialized features of a mature conventional dendritic cell. Mature conventional dendritic cells upregulate the surface expression of MHC molecules, chemokine receptors and adhesion molecules, and increase the number of dendrites (cytoplasmic protrusions) in preparation for migration to lymphoid organs where they present antigen to T cells. GO:0000046 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000046 GO:0000045 autophagosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000045 autophagic vacuole formation|PAS formation|autophagic vacuole assembly|autophagosome biosynthesis|autophagosome formation The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm. GO:0000044 obsolete ascorbate stabilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000044 vitamin C stabilization|ascorbate stabilization OBSOLETE. The reduction of the ascorbate free radical to a stable form. GO:0000043 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000043 GO:0000049 tRNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000049 base pairing with tRNA Interacting selectively and non-covalently with transfer RNA. GO:0000048 peptidyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000048 EC:2.3.2.12|Reactome:R-HSA-156912|MetaCyc:PEPTIDYLTRANSFERASE-RXN peptidyl-tRNA:aminoacyl-tRNA N-peptidyltransferase activity Catalysis of the reaction: peptidyl-tRNA(1) + aminoacyl-tRNA(2) = tRNA(1) + peptidylaminoacyl-tRNA(2). GO:0000047 obsolete Rieske iron-sulfur protein biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000047 Rieske iron-sulfur protein|Rieske iron-sulphur protein OBSOLETE. (Was not defined before being made obsolete). CHEBI:167116 oxidized 1-acyl-sn-glycero-3-phosphocholine zwitterion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_167116 CHEBI:167119 oxidized 2-acyl-sn-glycero-3-phosphocholine zwitterion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_167119 CHEBI:167118 oxidized N-(fatty acyl)-ethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_167118 PR:000001391 interleukin-4 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001391 B-cell stimulatory factor 1|binetrakin|IL-4|IGG1 induction factor|B-cell growth factor 1|lymphocyte stimulatory factor 1|BSF-1|pitrakinra|B-cell IgG differentiation factor|IL4 A protein that is a translation product of the human IL4 gene or a 1:1 ortholog thereof. GO:0000042 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000042 GO:0000041 transition metal ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000041 transition metal transport The directed movement of transition metal ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver. PR:000001393 interleukin-6 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001393 CTL differentiation factor|hybridoma growth factor|B-cell stimulatory factor 2|IL-6|CDF|interferon beta-2|interleukin HP-1|B-cell hybridoma growth factor|IFNB2|BSF-2|IL6|IFN-beta-2 A protein that is a translation product of the human IL6 gene or a 1:1 ortholog thereof. GO:0000040 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000040 CHEBI:167115 oxidized glycerophosphocholine zwitterion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_167115 PR:000001392 interleukin-5 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001392 eosinophil differentiation factor|BCGF-II|B-cell growth factor II|cytotoxic T-lymphocyte inducer|IL-5|TRF|B-cell differentiation factor I|T-cell replacing factor|IL5 A protein that is a translation product of the human IL5 gene or a 1:1 ortholog thereof. CHEBI:167114 2-hydroxydicarboxylate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_167114 PR:000001383 interleukin-22 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001383 IL-10-related T-cell-derived-inducible factor|Il22a|cytokine Zcyto18|IL-22a|Iltifa|ZCYTO18|IL-22|ILTIF|IL-TIF|IL-TIF alpha|interleukin-22a|IL22 A protein that is a translation product of the human IL22 gene or a 1:1 ortholog thereof. SO:0000837 UTR_region biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000837 UTR region A region of UTR. PR:000001387 interleukin-3 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001387 Csfmu|MCGF|multipotential colony-stimulating factor|IL3|mast cell growth factor|hematopoietic growth factor|P-cell-stimulating factor|IL-3 A protein that is a translation product of the human IL3 gene or a 1:1 ortholog thereof. SO:0000836 mRNA_region biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000836 mRNA region A region of an mRNA. SO:0000839 polypeptide_region biolink:SequenceFeature go-plus biosapiens|SOFA http://purl.obolibrary.org/obo/SO_0000839 site|region or site annotation|positional|positional polypeptide feature|region Biological sequence region that can be assigned to a specific subsequence of a polypeptide. PR:000001389 interleukin-33 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001389 NF-HEV|IL33|IL-1F11|NFHEV|interleukin-1 family member 11|IL1F11|C9orf26|nuclear factor from high endothelial venules|IL-33 A protein that is a translation product of the human IL33 gene or a 1:1 ortholog thereof. SO:0000833 transcript_region biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000833 transcript region A region of a transcript. SO:0000835 primary_transcript_region biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000835 primary transcript region A part of a primary transcript. SO:0000834 mature_transcript_region biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000834 mature transcript region A region of a mature transcript. SO:0000831 gene_member_region biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000831 gene member region A region of a gene. SO:0000830 chromosome_part biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000830 chromosome part|chromosomal_region|chromosomal region A region of a chromosome. GO:0000057 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000057 CHEBI:167120 oxidized 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine zwitterion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_167120 GO:0000056 ribosomal small subunit export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000056 ribosomal small subunit-nucleus export|ribosomal small subunit export out of nucleus|40S ribosomal subunit export from nucleus|30S ribosomal subunit export from nucleus|ribosomal small subunit export from cell nucleus|ribosomal small subunit transport from nucleus to cytoplasm The directed movement of a ribosomal small subunit from the nucleus into the cytoplasm. GO:0000055 ribosomal large subunit export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000055 ribosomal large subunit transport from nucleus to cytoplasm|ribosomal large subunit export from cell nucleus|60S ribosomal subunit export from nucleus|50S ribosomal subunit export from nucleus|ribosomal large subunit export out of nucleus|ribosomal large subunit-nucleus export The directed movement of a ribosomal large subunit from the nucleus into the cytoplasm. GO:0000054 ribosomal subunit export from nucleus biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0000054 ribosomal subunit transport from nucleus to cytoplasm|ribosomal subunit export out of nucleus|ribosomal subunit export from cell nucleus|ribosome export from nucleus|ribosomal subunit-nucleus export The directed movement of a ribosomal subunit from the nucleus into the cytoplasm. CHEBI:167121 oxidized 2-acyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_167121 GO:0000059 obsolete protein import into nucleus, docking biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000059 protein docking during protein-nucleus import|protein docking during protein import into nucleus|protein-nucleus import, docking|protein transport from cytoplasm to nucleus, docking|protein docking during protein transport from cytoplasm to nucleus OBSOLETE. A protein complex assembly process that contributes to protein import into the nucleus, and that results in the association of a cargo protein, a carrier protein such as an importin alpha/beta heterodimer, and a nucleoporin located at the periphery of the nuclear pore complex. GO:0000058 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000058 CHEBI:87373 pentyl propanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87373 CHEBI:143136 succinamate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_143136 GO:0000053 argininosuccinate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000053 argininosuccinate metabolism The chemical reactions and pathways involving argininosuccinate, 2-(N(omega)-arginino)succinate, an intermediate in the ornithine-urea cycle, where it is synthesized from citrulline and aspartate. GO:0000052 citrulline metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000052 citrulline metabolism The chemical reactions and pathways involving citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins. GO:0000051 obsolete urea cycle intermediate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000051 urea cycle intermediate metabolic process|urea cycle intermediate metabolism OBSOLETE. The chemical reactions and pathways involving any of the intermediate compounds involved in the urea cycle, a cyclic metabolic pathway that converts waste nitrogen in the form of ammonium to urea. GO:0000050 urea cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000050 Wikipedia:Urea_cycle ornithine cycle|urea biosynthesis|urea biosynthetic process The sequence of reactions by which arginine is synthesized from ornithine, then cleaved to yield urea and regenerate ornithine. The overall reaction equation is NH3 + CO2 + aspartate + 3 ATP + 2 H2O = urea + fumarate + 2 ADP + 2 phosphate + AMP + diphosphate. PR:000001395 interleukin-8 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001395 IL8|IL-8|protein 3-10C|emoctakin|neutrophil-activating protein 1|C-X-C motif chemokine 8|NAP-1|monocyte-derived neutrophil chemotactic factor|MONAP|MDNCF|monocyte-derived neutrophil-activating peptide|CXCL8|T-cell chemotactic factor|granulocyte chemotactic protein 1|GCP-1 A protein that is a translation product of the human CXCL8 gene or a 1:1 ortholog thereof. CHEBI:157772 epoxydocosatetraenoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_157772 CHEBI:157771 hydroperoxydocosapentaenoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_157771 PR:000025350 HSPC protein biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000025350 HSP90 An Hsp70 family chaperone that contains an ATPase and HSP90 domains. PR:000001397 interleukin-9 receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001397 IL-9 receptor|IL-9R|IL9R|CD129 A protein that is a translation product of the human IL9R gene or a 1:1 ortholog thereof. CHEBI:157770 short-chain primary fatty alcohol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_157770 PR:000001396 interleukin-9 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001396 IL-9|T-cell growth factor P40|IL9|cytokine P40 A protein that is a translation product of the human IL9 gene or a 1:1 ortholog thereof. CHEBI:157775 N-acyl-beta-D-galactosylphytosphingosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_157775 CHEBI:157774 epoxydocosahexaenoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_157774 CHEBI:157773 epoxydocosapentaenoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_157773 GO:0000024 maltose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000024 maltose anabolism|malt sugar biosynthesis|malt sugar biosynthetic process|maltose synthesis|maltose formation|maltose biosynthesis The chemical reactions and pathways resulting in the formation of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose). GO:0048002 antigen processing and presentation of peptide antigen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048002 peptide antigen processing and presentation|antigen presentation, peptide antigen The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC protein complex on its cell surface, including proteolysis and transport steps for the peptide antigen both prior to and following assembly with the MHC protein complex. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein. GO:0048001 erythrose-4-phosphate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048001 KEGG_REACTION:R01825|EC:1.2.1.72|RHEA:12056|MetaCyc:ERYTH4PDEHYDROG-RXN E4P dehydrogenase activity|GapB|erythrose 4-phosphate dehydrogenase activity|D-erythrose 4-phosphate:NAD+ oxidoreductase activity|E4PDH|Epd dehydrogenase activity Catalysis of the reaction: D-erythrose 4-phosphate + H(2)O + NAD(+) = 4-phospho-D-erythronate + 2 H(+) + NADH. GO:0000023 maltose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000023 malt sugar metabolism|malt sugar metabolic process|maltose metabolism The chemical reactions and pathways involving the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose), an intermediate in the catabolism of glycogen and starch. GO:0000022 mitotic spindle elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000022 microtubule sliding involved in mitotic spindle elongation|spindle elongation during mitosis The cell cycle process in which the distance is lengthened between poles of the mitotic spindle. Mitotic spindle elongation begins during mitotic prophase and ends during mitotic anaphase B. GO:0048000 isoflavone 3'-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048000 EC:1.14.14.88|MetaCyc:RXN-3762|RHEA:22960 isoflavone 3'-monooxygenase activity|formononetin,NADPH:oxygen oxidoreductase (3'-hydroxylating) Catalysis of the reaction: formononetin + NADPH + O2 = calycosin + NADP+ + H2O. GO:0000021 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000021 GO:0000028 ribosomal small subunit assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000028 30S ribosomal subunit assembly|40S ribosomal subunit assembly The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the small ribosomal subunit. GO:0000027 ribosomal large subunit assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000027 50S ribosomal subunit assembly|60S ribosomal subunit assembly The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit. GO:0000026 alpha-1,2-mannosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000026 Reactome:R-HSA-4720478|Reactome:R-HSA-4551297|Reactome:R-HSA-446187|Reactome:R-HSA-446215|Reactome:R-HSA-446216|Reactome:R-HSA-9035514 Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->2) linkage. CHEBI:7051 myosmine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_7051 GO:0000025 maltose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000025 MetaCyc:MALTOSECAT-PWY maltose hydrolysis|malt sugar catabolism|malt sugar catabolic process|maltose degradation|maltose breakdown The chemical reactions and pathways resulting in the breakdown of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose). GO:0048009 insulin-like growth factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048009 IGF receptor signaling pathway|IGF receptor signalling pathway The series of molecular signals generated as a consequence of the insulin-like growth factor receptor binding to one of its physiological ligands. GO:0048008 platelet-derived growth factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048008 PDGF receptor signalling pathway|PDGF receptor signaling pathway|PDGFR signaling pathway The series of molecular signals generated as a consequence of a platelet-derived growth factor receptor binding to one of its physiological ligands. GO:0048007 antigen processing and presentation, exogenous lipid antigen via MHC class Ib biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048007 antigen presentation, exogenous peptide antigen|exogenous lipid antigen processing and presentation via MHC class Ib The process in which an antigen-presenting cell expresses lipid antigen of exogenous origin in association with an MHC class Ib protein complex on its cell surface. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family. GO:0048006 antigen processing and presentation, endogenous lipid antigen via MHC class Ib biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048006 endogenous lipid antigen processing and presentation via MHC class Ib|antigen presentation, endogenous lipid antigen The process in which an antigen-presenting cell expresses lipid antigen of endogenous origin in association with an MHC class Ib protein complex on its cell surface. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family. GO:0000020 obsolete negative regulation of recombination within rDNA repeats biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000020 negative regulation of recombination within rDNA repeats OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination within the DNA of the genes coding for ribosomal RNA. GO:0048005 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048005 GO:0048004 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048004 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048003 antigen presentation, lipid antigen|lipid antigen processing and presentation via MHC class Ib The process in which an antigen-presenting cell expresses lipid antigen in association with an MHC class Ib protein complex on its cell surface, including lipid extraction, degradation, and transport steps for the lipid antigen both prior to and following assembly with the MHC protein complex. The lipid antigen may originate from an endogenous or exogenous source of lipid. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family. PR:000001370 interleukin-13 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001370 NC30|IL-13|T-cell activation protein P600|IL13 A protein that is a translation product of the human IL13 gene or a 1:1 ortholog thereof. Interleukin-13 is a pleiotropic cytokine which may be important in the regulation of the inflammatory and immune responses. It inhibits inflammatory cytokine production and synergises with IL-2 in regulating interferon-gamma synthesis. The sequences of IL-4 and IL-13 are distantly related. CHEBI:133793 prostaglandin G1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133793 CHEBI:133796 (4Z,7Z,10Z,13Z,15E,17S)-17-hydroperoxydocosapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133796 CHEBI:133795 (4Z,7Z,10Z,13Z,15E,17S,19Z)-17-hydroperoxydocosahexaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133795 PR:000001366 interleukin-11 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001366 IL11|adipogenesis inhibitory factor|AGIF|IL-11|oprelvekin A protein that is a translation product of the human IL11 gene or a 1:1 ortholog thereof. CHEBI:133798 (7Z,10Z,12E,16Z,19Z)-14-hydroperoxydocosapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133798 CHEBI:133797 (7Z,10Z,13Z,15E,19Z)-17-hydroperoxydocosapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133797 PR:000001368 interleukin-12 subunit alpha biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001368 IL-12 subunit p35|NKSF1|cytotoxic lymphocyte maturation factor 35 kDa subunit|IL12A|IL-12A|NK cell stimulatory factor chain 1|CLMF p35 A protein that is a translation product of the human IL12A gene or a 1:1 ortholog thereof. It associates with interleukin-12 subunit beta to form the interleukin-23. Interleukin-12 subunit alpha associates with interleukin-27 subunit beta to form the interleukin-35. CHEBI:133799 (4Z,7Z,10Z,12E,16Z)-14-hydroperoxydocosapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133799 CHEBI:143129 primary fatty amide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_143129 PR:000001369 interleukin-12 subunit beta biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001369 NKSF2|IL12B|IL-12 subunit p40|cytotoxic lymphocyte maturation factor 40 kDa subunit|IL-12B|NK cell stimulatory factor chain 2|CLMF p40 A protein that is a translation product of the human IL12B gene or a 1:1 ortholog thereof. Interleukin-12 subunit beta associates with interleukin-12 subunit alpha or interleukin-23 subunit alpha to form the interleukin-23. CHEBI:157766 2-hydroxy-fatty acyl-CoA(4-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_157766 GO:0000029 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000029 CHEBI:133790 linolenate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133790 CHEBI:133792 erythronate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133792 CHEBI:157763 polyprenol phosphate anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_157763 CHEBI:133791 2-hydroxybutyrates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133791 GO:0048013 ephrin receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048013 Eph receptor signalling pathway|Eph receptor signaling pathway The series of molecular signals generated as a consequence of an ephrin receptor binding to an ephrin. GO:0000035 acyl binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000035 acyl-CoA or acyl binding Interacting selectively and non-covalently with an acyl group, any group formally derived by removal of the hydroxyl group from the acid function of a carboxylic acid. GO:0000034 adenine deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000034 RHEA:23688|EC:3.5.4.2|MetaCyc:ADENINE-DEAMINASE-RXN adenine aminohydrolase activity|adenase activity|ADase activity|adenine aminase activity Catalysis of the reaction: adenine + H2O = hypoxanthine + NH3. GO:0048012 hepatocyte growth factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048012 Met signaling pathway|HGF receptor signaling pathway|HGF receptor signalling pathway The series of molecular signals generated as a consequence of the hepatocyte growth factor receptor binding to one of its physiological ligands. GO:0048011 neurotrophin TRK receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048011 tropomyosin-receptor-kinase signaling|TrkB signaling pathway|TrkA signaling pathway|TrkC signaling pathway A series of molecular signals initiated by the binding of a neurotrophin to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0000033 alpha-1,3-mannosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000033 Reactome:R-HSA-446208|Reactome:R-HSA-4720473|Reactome:R-HSA-4549368|Reactome:R-HSA-446188 Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->3) linkage. GO:0000032 cell wall mannoprotein biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000032 cell wall mannoprotein formation|cell wall mannoprotein biosynthesis|cell wall mannoprotein anabolism|cell wall mannoprotein synthesis The chemical reactions and pathways resulting in the formation of cell wall mannoproteins, any cell wall protein that contains covalently bound mannose residues. GO:0048010 vascular endothelial growth factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048010 VEGFR signaling pathway|VEGF receptor signalling pathway|VEGF receptor signaling pathway Any series of molecular signals initiated by the binding of an extracellular ligand to a vascular endothelial growth factor receptor (VEGFR) located on the surface of the receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0000039 obsolete plasma membrane long-chain fatty acid transporter biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000039 plasma membrane long-chain fatty acid transporter OBSOLETE. (Was not defined before being made obsolete). GO:0000038 very long-chain fatty acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000038 very-long-chain fatty acid metabolism|very long chain fatty acid metabolic process|very-long-chain fatty acid metabolic process The chemical reactions and pathways involving a fatty acid which has a chain length greater than C22. CHEBI:87391 N-icosanoylglycinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87391 GO:0000037 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000037 GO:0000036 acyl carrier activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000036 ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process Binding an acyl group and presenting it for processing or offloading to a cognate enzyme. Covalently binds the acyl group via a phosphopantetheine prosthetic group and mediates protein-protein interactions with the enzyme conferring specificity. The acyl carrier protein (ACP) presents substrates to enzymes involved in fatty acid biosynthesis or in polyketide secondary metabolite biosynthesis. CHEBI:157759 glycosylmonoacylglycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_157759 GO:0048019 receptor antagonist activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048019 receptor ligand activity The activity of a gene product that interacts with a receptor to decrease the ability of the receptor agonist to bind and activate the receptor. GO:0048018 receptor ligand activity biolink:MolecularActivity go-plus goslim_drosophila|goslim_chembl http://purl.obolibrary.org/obo/GO_0048018 receptor agonist activity|signaling molecule|signaling receptor ligand activity|vitamin D receptor activator activity The activity of a gene product that interacts with a receptor to effect a change in the activity of the receptor. Ligands may be produced by the same, or different, cell that expresses the receptor. Ligands may diffuse extracellularly from their point of origin to the receiving cell, or remain attached to an adjacent cell surface (e.g. Notch ligands). GO:0048017 inositol lipid-mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048017 inositol lipid-mediated signal transduction|inositol lipid-mediated signalling|inositol phospholipid-mediated signaling A series of molecular signals in which a cell uses an inositol-containing lipid to convert a signal into a response. Inositol lipids include the phosphoinositides (phosphatidylinositol and its phosphorylated derivatives), ceramides containing inositol, and inositol glycolipids. GO:0000031 mannosylphosphate transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000031 Catalysis of the transfer of a mannosylphosphate group from one compound to another. GO:0000030 mannosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000030 Reactome:R-HSA-162797|Reactome:R-HSA-162830|Reactome:R-HSA-446198|Reactome:R-HSA-4720497 Catalysis of the transfer of a mannosyl group to an acceptor molecule, typically another carbohydrate or a lipid. GO:0048016 inositol phosphate-mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048016 inositol phosphate-mediated signalling Any intracellular signal transduction in which the signal is passed on within the cell via an inositol phosphate. Includes production of the inositol phosphate, and downstream effectors that further transmit the signal within the cell. Inositol phosphates are a group of mono- to poly-phosphorylated inositols, and include inositol monophosphate (IP), inositol trisphosphate (IP3), inositol pentakisphosphate (IP5) and inositol hexaphosphate (IP6). GO:0048015 phosphatidylinositol-mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048015 inositol phospholipid-mediated signaling|phosphatidylinositol-mediated signalling|phosphatidylinositol-mediated signal transduction|phosphoinositide-mediated signalling|phosphoinositide-mediated signaling A series of molecular signals in which a cell uses a phosphatidylinositol-mediated signaling to convert a signal into a response. Phosphatidylinositols include phosphatidylinositol (PtdIns) and its phosphorylated derivatives. PR:000001382 interleukin-21 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001382 IL-21|Za11|IL21 A protein that is a translation product of the human IL21 gene or a 1:1 ortholog thereof. CHEBI:167148 1-linoleoyl-2-acyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_167148 GO:0048014 Tie signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048014 Tie receptor signaling pathway|angiopoietin-Tie signaling pathway|Tek receptor signaling|Tie receptor signalling pathway|angiopoietin/Tie signaling pathway The series of molecular signals generated as a consequence of a Tie protein (a receptor) binding to one of its physiological ligands (an angiopoietin). PR:000001373 interleukin-15 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001373 IL-15|IL15 A protein that is a translation product of the human IL15 gene or a 1:1 ortholog thereof. CHEBI:157750 heparan sulfate polyanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_157750 PR:000001374 interleukin-16 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001374 IL16 A protein that is a translation product of the human IL16 gene or a 1:1 ortholog thereof. PR:000001376 interleukin-18 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001376 IL-18|IL-1 gamma|IL18|interferon gamma-inducing factor|interleukin-1 gamma|IFN-gamma-inducing factor|IL1F4|IGIF|iboctadekin A protein that is a translation product of the human IL18 gene or a 1:1 ortholog thereof. PR:000001379 interleukin-2 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001379 IL2|TCGF|IL-2|T-cell growth factor|aldesleukin A protein that is a translation product of the human IL2 gene or a 1:1 ortholog thereof. Interleukin-2 has a dual role in maintaining tolerance and contributing to immunity. CHEBI:157758 1-acyl-2-hydroxy-sn-glycero-3-phospho-(N-acyl)-serine(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_157758 CHEBI:157757 1,2-diacyl-sn-glycero-3-phospho-(N-acyl)-serine(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_157757 SO:0000842 gene_component_region biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000842 gene component region A region of a gene that has a specific function. GO:0048024 regulation of mRNA splicing, via spliceosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048024 regulation of pre-mRNA splicing|regulation of nuclear mRNA splicing via U2-type spliceosome|regulation of nuclear mRNA splicing, via spliceosome Any process that modulates the frequency, rate or extent of mRNA splicing via a spliceosomal mechanism. GO:0000002 mitochondrial genome maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000002 The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome. GO:0000001 mitochondrion inheritance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000001 mitochondrial inheritance The distribution of mitochondria, including the mitochondrial genome, into daughter cells after mitosis or meiosis, mediated by interactions between mitochondria and the cytoskeleton. GO:0048023 positive regulation of melanin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048023 upregulation of melanin biosynthetic process|stimulation of melanin biosynthetic process|activation of melanin biosynthetic process|up-regulation of melanin biosynthetic process|positive regulation of melanin anabolism|positive regulation of melanin biosynthesis|positive regulation of melanin synthesis|up regulation of melanin biosynthetic process|positive regulation of melanin formation Any process that activates or increases the rate or extent of the chemical reactions and pathways resulting in the formation of melanin. GO:0048022 negative regulation of melanin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048022 negative regulation of melanin formation|down regulation of melanin biosynthetic process|inhibition of melanin biosynthetic process|negative regulation of melanin biosynthesis|down-regulation of melanin biosynthetic process|negative regulation of melanin anabolism|negative regulation of melanin synthesis|downregulation of melanin biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin. GO:0048021 regulation of melanin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048021 regulation of melanin biosynthesis|regulation of melanin anabolism|regulation of melanin synthesis|regulation of melanin formation Any process that alters the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin. GO:0000006 high-affinity zinc transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000006 high-affinity zinc uptake transmembrane transporter activity|high affinity zinc uptake transmembrane transporter activity Enables the transfer of zinc ions (Zn2+) from one side of a membrane to the other, probably powered by proton motive force. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. GO:0048020 CCR chemokine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048020 CCR chemokine receptor ligand|beta chemokine receptor ligand|beta chemokine receptor binding Interacting selectively and non-covalently with a CCR chemokine receptor. GO:0000005 obsolete ribosomal chaperone activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000005 ribosomal chaperone activity OBSOLETE. Assists in the correct assembly of ribosomes or ribosomal subunits in vivo, but is not a component of the assembled ribosome when performing its normal biological function. GO:0000004 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000004 GO:0000003 reproduction biolink:BiologicalProcess go-plus goslim_plant|goslim_pir|goslim_generic|goslim_flybase_ribbon|goslim_chembl|goslim_agr http://purl.obolibrary.org/obo/GO_0000003 Wikipedia:Reproduction reproductive physiological process The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms. GO:0048029 monosaccharide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048029 Interacting selectively and non-covalently with any monosaccharide. Monosaccharides are the simplest carbohydrates; they are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H[CHOH]nC(=O)[CHOH]mH with three or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides. GO:0048028 galacturonan binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048028 polygalacturonide binding Interacting selectively and non-covalently with any simple or complex galacturonan. Galacturonan is any glycan composed solely of galacturonic acid residues, a specific type of glycuronan, and a constituent of some pectins. GO:0048027 mRNA 5'-UTR binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048027 mRNA 5' UTR binding Interacting selectively and non-covalently with the 5' untranslated region of an mRNA molecule. GO:0048026 positive regulation of mRNA splicing, via spliceosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048026 up regulation of nuclear mRNA splicing via U2-type spliceosome|up regulation of nuclear mRNA splicing, via spliceosome|positive regulation of pre-mRNA splicing|positive regulation of nuclear mRNA splicing via U2-type spliceosome|activation of nuclear mRNA splicing via U2-type spliceosome|stimulation of nuclear mRNA splicing via U2-type spliceosome|upregulation of nuclear mRNA splicing, via spliceosome|up-regulation of nuclear mRNA splicing via U2-type spliceosome|positive regulation of nuclear mRNA splicing, via spliceosome|stimulation of nuclear mRNA splicing, via spliceosome|up-regulation of nuclear mRNA splicing, via spliceosome|activation of nuclear mRNA splicing, via spliceosome|upregulation of nuclear mRNA splicing via U2-type spliceosome Any process that activates or increases the rate or extent of mRNA splicing via a spliceosomal mechanism. GO:0048025 negative regulation of mRNA splicing, via spliceosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048025 down regulation of nuclear mRNA splicing via U2-type spliceosome|down-regulation of nuclear mRNA splicing, via spliceosome|downregulation of nuclear mRNA splicing via U2-type spliceosome|downregulation of nuclear mRNA splicing, via spliceosome|negative regulation of nuclear mRNA splicing via U2-type spliceosome|negative regulation of pre-mRNA splicing|down-regulation of nuclear mRNA splicing via U2-type spliceosome|down regulation of nuclear mRNA splicing, via spliceosome|negative regulation of nuclear mRNA splicing, via spliceosome|inhibition of nuclear mRNA splicing, via spliceosome|inhibition of nuclear mRNA splicing via U2-type spliceosome Any process that stops, prevents or reduces the rate or extent of mRNA splicing via a spliceosomal mechanism. CHEBI:133772 (S)-PGJ2-S-glutathione conjugate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133772 CHEBI:133771 (R)-PGJ2-S-glutathione conjugate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133771 CHEBI:133773 pimelate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133773 CHEBI:133775 dimethylargininium(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133775 CHEBI:133778 1alpha-hydroxyandrost-4-ene-3,17-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133778 GO:0000009 alpha-1,6-mannosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000009 EC:2.4.1.232|Reactome:R-HSA-449718 1,6-alpha-mannosyltransferase activity Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->6) linkage. GO:0000008 obsolete thioredoxin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000008 thioredoxin OBSOLETE. A small disulfide-containing redox protein that serves as a general protein disulfide oxidoreductase. Interacts with a broad range of proteins by a redox mechanism, based on the reversible oxidation of 2 cysteine thiol groups to a disulfide, accompanied by the transfer of 2 electrons and 2 protons. The net result is the covalent interconversion of a disulfide and a dithiol. GO:0000007 low-affinity zinc ion transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000007 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Zn2+ = Zn2+, probably powered by proton motive force. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations. CHEBI:157740 N-(fatty acyl)-dopamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_157740 GO:0048035 heme o catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048035 heme o breakdown|haem o catabolism|haem o catabolic process|heme o catabolism|heme o degradation The chemical reactions and pathways resulting in the breakdown of heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle. GO:0000013 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000013 GO:0048034 heme O biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048034 heme O biosynthesis|heme O anabolism|haem O biosynthesis|haem O biosynthetic process|heme O synthesis|heme O formation The chemical reactions and pathways resulting in the formation of heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle. GO:0000012 single strand break repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000012 The repair of single strand breaks in DNA. Repair of such breaks is mediated by the same enzyme systems as are used in base excision repair. GO:0048033 heme o metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048033 heme o metabolism|haem o metabolism|haem o metabolic process The chemical reactions and pathways involving heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle. GO:0000011 vacuole inheritance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000011 The distribution of vacuoles into daughter cells after mitosis or meiosis, mediated by interactions between vacuoles and the cytoskeleton. SO:0000871 polyadenylated_mRNA biolink:SequenceFeature go-plus http://purl.obolibrary.org/obo/SO_0000871 polyadenylated mRNA An mRNA that is polyadenylated. GO:0048032 galacturonate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048032 galacturonic acid binding Interacting selectively and non-covalently with any galacturonate. Galacturonate is the anion of galacturonic acid, the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group. GO:0000010 trans-hexaprenyltranstransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000010 RHEA:20836 Catalysis of the reaction: all-trans-hexaprenyl diphosphate + isopentenyl diphosphate = all-trans-heptaprenyl diphosphate + diphosphate. GO:0048031 trisaccharide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048031 Interacting selectively and non-covalently with any trisaccharide. Trisaccharides are sugars composed of three monosaccharide units. GO:0000017 alpha-glucoside transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000017 The directed movement of alpha-glucosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alpha-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in an alpha configuration. GO:0048030 disaccharide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048030 Interacting selectively and non-covalently with any disaccharide. Disaccharides are sugars composed of two monosaccharide units. GO:0000016 lactase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000016 Reactome:R-HSA-189062|EC:3.2.1.108|RHEA:10076|Reactome:R-HSA-5658001|MetaCyc:LACTASE-RXN lactose galactohydrolase activity|lactase-phlorizin hydrolase activity Catalysis of the reaction: lactose + H2O = D-glucose + D-galactose. GO:0000015 phosphopyruvate hydratase complex biolink:CellularComponent go-plus goslim_metagenomics http://purl.obolibrary.org/obo/GO_0000015 enolase complex A multimeric enzyme complex, usually a dimer or an octamer, that catalyzes the conversion of 2-phospho-D-glycerate to phosphoenolpyruvate and water. GO:0000014 single-stranded DNA endodeoxyribonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000014 ssDNA-specific endodeoxyribonuclease activity|single-stranded DNA specific endodeoxyribonuclease activity Catalysis of the hydrolysis of ester linkages within a single-stranded deoxyribonucleic acid molecule by creating internal breaks. GO:0048039 ubiquinone binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048039 coenzyme Q6 binding|coenzyme Q binding Interacting selectively and non-covalently with ubiquinone, a quinone derivative with a tail of isoprene units. GO:0048038 quinone binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048038 Interacting selectively and non-covalently with a quinone, any member of a class of diketones derivable from aromatic compounds by conversion of two CH groups into CO groups with any necessary rearrangement of double bonds. GO:0048037 obsolete cofactor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048037 OBSOLETE. Interacting selectively and non-covalently with a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate. GO:0048036 central complex development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048036 central body development The process whose specific outcome is the progression of the central complex over time, from its formation to the mature structure. The central complex region of the insect brain is thought to be crucial for control of locomotive behavior. Located in the middle of the two protocerebral hemispheres, it comprises four neuropilar regions, the fan-shaped body, the ellipsoid body, the protocerebral bridge and the paired noduli. GO:0000019 regulation of mitotic recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000019 regulation of recombination within rDNA repeats Any process that modulates the frequency, rate or extent of DNA recombination during mitosis. GO:0000018 regulation of DNA recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000018 Any process that modulates the frequency, rate or extent of DNA recombination, a DNA metabolic process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. SO:0000862 capped_mRNA biolink:SequenceFeature go-plus http://purl.obolibrary.org/obo/SO_0000862 capped mRNA An mRNA that is capped. GO:0048046 apoplast biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0048046 Wikipedia:Apoplast The cell membranes and intracellular regions in a plant are connected through plasmodesmata, and plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it. GO:0048045 trans-pentaprenyltranstransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048045 KEGG_REACTION:R05613|RHEA:22632 all-trans-hexaprenyl-diphosphate synthase activity|hexaprenyl diphosphate synthase activity|hexaprenyl pyrophosphate synthetase activity|all-trans-pentaprenyl-diphosphate:isopentenyl-diphosphate pentaprenyltranstransferase activity Catalysis of the reaction: all-trans-pentaprenyl diphosphate + isopentenyl diphosphate = all-trans-hexaprenyl diphosphate + diphosphate. CHEBI:7091 N-(5-phospho-beta-D-ribosyl)anthranilic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_7091 GO:0048044 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048044 GO:0048043 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048043 GO:0048042 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048042 GO:0048041 focal adhesion assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048041 adhesion plaque assembly|focal adhesion formation The aggregation and bonding together of a set of components to form a focal adhesion, a complex of intracellular signaling and structural proteins that provides a structural link between the internal actin cytoskeleton and the ECM, and also function as a locus of signal transduction activity. GO:0048040 UDP-glucuronate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048040 EC:4.1.1.35|KEGG_REACTION:R01384|MetaCyc:UDP-GLUCURONATE-DECARBOXYLASE-RXN|RHEA:23916 uridine-diphosphoglucuronate decarboxylase activity|UDP-D-glucuronate carboxy-lyase activity|UDPglucuronate decarboxylase activity|UDP-glucuronic acid decarboxylase activity|UDP-D-glucuronate carboxy-lyase (UDP-D-xylose-forming) Catalysis of the reaction: H(+) + UDP-alpha-D-glucuronate = CO(2) + UDP-alpha-D-xylose. GO:1903209 positive regulation of oxidative stress-induced cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903209 enhancement of oxidative stress-induced cell death|up regulation of cell death in response to oxidative stress|upregulation of cell death in response to oxidative stress|positive regulation of cell death in response to oxidative stress|activation of cell death in response to oxidative stress|up-regulation of cell death in response to oxidative stress Any process that activates or increases the frequency, rate or extent of oxidative stress-induced cell death. CHEBI:38390 9,11,15-octadecatrienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38390 GO:1903208 negative regulation of hydrogen peroxide-induced neuron death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903208 down regulation of neuron death in response to H2O2|inhibition of neuron death in response to H2O2|protection against hydrogen peroxide-induced neuron death|down-regulation of hydrogen peroxide-induced neuron death|downregulation of neuronal cell death in response to hydrogen peroxide|down-regulation of neuron death in response to hydrogen peroxide|down regulation of neuronal cell death in response to hydrogen peroxide|negative regulation of neuron death in response to hydrogen peroxide|inhibition of neuronal cell death in response to hydrogen peroxide|downregulation of hydrogen peroxide-induced neuron death|neuroprotection against H2O2-induced cell death|inhibition of neuron death in response to hydrogen peroxide|down regulation of hydrogen peroxide-induced neuron death|inhibition of hydrogen peroxide-induced neuron death|negative regulation of neuron death in response to H2O2|down-regulation of neuron death in response to H2O2|neuroprotection against hydrogen peroxide|protection against H2O2-induced neuron death|down regulation of neuron death in response to hydrogen peroxide|downregulation of neuron death in response to H2O2|down-regulation of neuronal cell death in response to hydrogen peroxide|negative regulation of neuronal cell death in response to hydrogen peroxide|downregulation of neuron death in response to hydrogen peroxide Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide-induced neuron death. GO:1903207 regulation of hydrogen peroxide-induced neuron death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903207 regulation of neuronal cell death in response to hydrogen peroxide|regulation of neuron death in response to H2O2|regulation of neuron death in response to hydrogen peroxide Any process that modulates the frequency, rate or extent of hydrogen peroxide-induced neuron death. GO:1903206 negative regulation of hydrogen peroxide-induced cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903206 downregulation of hydrogen peroxide-mediated cell death|negative regulation of cell death in response to H2O2|down-regulation of cell death in response to H2O2|protection against H2O2-induced cell death|down regulation of cell death in response to hydrogen peroxide|negative regulation of hydrogen peroxide-mediated cell death|down-regulation of hydrogen peroxide-mediated cell death|downregulation of cell death in response to H2O2|downregulation of cell death in response to hydrogen peroxide|down regulation of cell death in response to H2O2|inhibition of cell death in response to H2O2|protection against hydrogen peroxide-induced cell death|inhibition of hydrogen peroxide-mediated cell death|down-regulation of cell death in response to hydrogen peroxide|negative regulation of cell death in response to hydrogen peroxide|inhibition of cell death in response to hydrogen peroxide|down regulation of hydrogen peroxide-mediated cell death Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide-induced cell death. GO:1903205 regulation of hydrogen peroxide-induced cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903205 regulation of cell death in response to hydrogen peroxide|regulation of cell death in response to H2O2|protection against hydrogen peroxide-mediated cell death|regulation of hydrogen peroxide-mediated cell death Any process that modulates the frequency, rate or extent of hydrogen peroxide-induced cell death. GO:1903204 negative regulation of oxidative stress-induced neuron death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903204 down regulation of oxidative stress-induced neuron death|downregulation of oxidative stress-induced neuron death|down regulation of neuronal cell death in response to oxidative stress|neuronal protection under oxidative stress|down-regulation of neuron death in response to oxidative stress|neuroprotection against oxidative stress|downregulation of neuronal cell death in response to oxidative stress|down-regulation of oxidative stress-induced neuron death|downregulation of neuron death in response to oxidative stress|inhibition of oxidative stress-induced neuron death|negative regulation of neuronal cell death in response to oxidative stress|down-regulation of neuronal cell death in response to oxidative stress|down regulation of neuron death in response to oxidative stress|inhibition of neuron death in response to oxidative stress|inhibition of neuronal cell death in response to oxidative stress Any process that stops, prevents or reduces the frequency, rate or extent of oxidative stress-induced neuron death. GO:1903203 regulation of oxidative stress-induced neuron death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903203 regulation of neuronal cell death in response to oxidative stress|regulation of neuron death in response to oxidative stress Any process that modulates the frequency, rate or extent of oxidative stress-induced neuron death. GO:1903202 negative regulation of oxidative stress-induced cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903202 downregulation of cell death in response to oxidative stress|down regulation of cell death in response to oxidative stress|inhibition of cell death in response to oxidative stress|protection against oxidative stress-induced cell death|down-regulation of cell death in response to oxidative stress|negative regulation of cell death in response to oxidative stress Any process that stops, prevents or reduces the frequency, rate or extent of oxidative stress-induced cell death. GO:0048049 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048049 GO:1903201 regulation of oxidative stress-induced cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903201 regulation of cell death in response to oxidative stress Any process that modulates the frequency, rate or extent of oxidative stress-induced cell death. GO:0048048 embryonic eye morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048048 The process occurring in the embryo by which the anatomical structures of the post-embryonic eye are generated and organized. GO:1903200 positive regulation of L-dopa decarboxylase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903200 up-regulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity|upregulation of DOPA decarboxylase activity|upregulation of L-dopa decarboxylase activity|upregulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity|upregulation of DDC activity|up regulation of DOPA decarboxylase activity|up regulation of L-dopa decarboxylase activity|activation of DOPA decarboxylase activity|activation of DDC activity|positive regulation of DOPA decarboxylase activity|activation of L-dopa decarboxylase activity|up-regulation of DDC activity|up regulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity|activation of 4-dihydroxyl-L-phenylalanine decarboxylase activity|positive regulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity|positive regulation of DDC activity|up-regulation of DOPA decarboxylase activity|up-regulation of L-dopa decarboxylase activity|up regulation of DDC activity Any process that activates or increases the frequency, rate or extent of L-dopa decarboxylase activity. GO:0048047 mating behavior, sex discrimination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048047 mating behaviour, sex discrimination The behavior of individuals for the purpose of discriminating between the sexes, for the purpose of finding a suitable mating partner. GO:1903210 glomerular visceral epithelial cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903210 glomerular podocyte apoptosis|glomerular podocyte apoptotic process|podocyte apoptosis|podocyte apoptotic process|glomerular visceral epithelial cell apoptosis Any apoptotic process in a glomerular visceral epithelial cell. CHEBI:133752 epsilon-(gamma-glutamyl)lysine dizwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133752 CHEBI:38382 9,11,13-octadecatrienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38382 CHEBI:38387 9,11,15-octadecatrienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38387 GO:0048057 R3/R4 development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048057 The process whose specific outcome is the progression of the R3 and R4 pair of photoreceptors in the eye over time, from their formation to the mature structures. R3 and R4 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster. GO:0048056 R3/R4 cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048056 The process in which relatively unspecialized cells acquire the specialized features of R3 and R4 photoreceptors. An example of this process is found in Drosophila melanogaster. GO:0048055 R2/R5 development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048055 The process whose specific outcome is the progression of the R2 and R5 pair of photoreceptors in the eye over time, from their formation to the mature structures. R2 and R5 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster. GO:0048054 R2/R5 cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048054 The process in which relatively unspecialized cells acquire the specialized features of R2 and R5 photoreceptors. An example of this process is found in Drosophila melanogaster. GO:0048053 R1/R6 development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048053 The process whose specific outcome is the progression of the R1 and R6 pair of photoreceptors in the eye over time, from their formation to the mature structures. R1 and R6 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster. GO:0048052 R1/R6 cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048052 The process in which relatively unspecialized cells acquire the specialized features of R1 and R6 photoreceptors. An example of this process is found in Drosophila melanogaster. GO:0048051 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048051 GO:1903219 negative regulation of malate dehydrogenase (decarboxylating) (NADP+) activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903219 downregulation of 'malic' enzyme|downregulation of NADP-linked decarboxylating malic enzyme|down-regulation of malate dehydrogenase (decarboxylating) (NADP+) activity|inhibition of NADP-specific malic enzyme|down regulation of NADP-specific malate dehydrogenase activity|down-regulation of NADP-malic enzyme activity|negative regulation of NADP-malic enzyme activity|down regulation of 'malic' enzyme|down regulation of NADP-linked decarboxylating malic enzyme|downregulation of NADP-specific malate dehydrogenase activity|inhibition of malate dehydrogenase (decarboxylating) (NADP+) activity|down-regulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|down-regulation of malate dehydrogenase (NADP, decarboxylating)|negative regulation of malate dehydrogenase (NADP, decarboxylating)|negative regulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|down regulation of L-malate:NADP oxidoreductase activity|inhibition of 'malic' enzyme|inhibition of NADP-linked decarboxylating malic enzyme|downregulation of NADP-malic enzyme activity|negative regulation of NADP-specific malic enzyme|down-regulation of NADP-specific malic enzyme|downregulation of L-malate:NADP oxidoreductase activity|down-regulation of NADP-specific malate dehydrogenase activity|negative regulation of NADP-specific malate dehydrogenase activity|negative regulation of malate dehydrogenase (decarboxylating, NADP)|down-regulation of malate dehydrogenase (decarboxylating, NADP)|down regulation of NADP-malic enzyme activity|inhibition of NADP-malic enzyme activity|downregulation of malate dehydrogenase (NADP, decarboxylating)|downregulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|down regulation of malate dehydrogenase (decarboxylating) (NADP+) activity|inhibition of NADP-specific malate dehydrogenase activity|downregulation of NADP-specific malic enzyme|down-regulation of 'malic' enzyme|down regulation of malate dehydrogenase (NADP, decarboxylating)|down regulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|negative regulation of 'malic' enzyme|downregulation of malate dehydrogenase (decarboxylating) (NADP+) activity|inhibition of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|down-regulation of NADP-linked decarboxylating malic enzyme|negative regulation of L-malate:NADP oxidoreductase activity|negative regulation of NADP-linked decarboxylating malic enzyme|inhibition of malate dehydrogenase (NADP, decarboxylating)|down-regulation of L-malate:NADP oxidoreductase activity|downregulation of malate dehydrogenase (decarboxylating, NADP)|down regulation of NADP-specific malic enzyme|down regulation of malate dehydrogenase (decarboxylating, NADP)|inhibition of L-malate:NADP oxidoreductase activity|inhibition of malate dehydrogenase (decarboxylating, NADP) Any process that stops, prevents or reduces the frequency, rate or extent of malate dehydrogenase (decarboxylating) (NADP+) activity. GO:0048050 post-embryonic eye morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048050 The process, occurring after embryonic development, by which the anatomical structures of the eye are generated and organized. The eye is the organ of sight. GO:1903218 regulation of malate dehydrogenase (decarboxylating) (NADP+) activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903218 regulation of 'malic' enzyme|regulation of NADP-linked decarboxylating malic enzyme|regulation of NADP-specific malate dehydrogenase activity|regulation of L-malate:NADP oxidoreductase activity|regulation of NADP-malic enzyme activity|regulation of malate dehydrogenase (NADP, decarboxylating)|regulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|regulation of NADP-specific malic enzyme|regulation of malate dehydrogenase (decarboxylating, NADP) Any process that modulates the frequency, rate or extent of malate dehydrogenase (decarboxylating) (NADP+) activity. CHEBI:133769 (S)-PGA2-S-glutathione conjugate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133769 GO:1903217 negative regulation of protein processing involved in protein targeting to mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903217 inhibition of protein processing involved in protein targeting to mitochondrion|inhibition of mitochondrial protein processing during import|down regulation of protein processing involved in protein targeting to mitochondrion|downregulation of protein processing involved in protein targeting to mitochondrion|negative regulation of mitochondrial protein processing during import|down-regulation of mitochondrial protein processing during import|down-regulation of protein processing involved in protein targeting to mitochondrion|downregulation of mitochondrial protein processing during import|down regulation of mitochondrial protein processing during import Any process that stops, prevents or reduces the frequency, rate or extent of protein processing involved in protein targeting to mitochondrion. CHEBI:133768 (R)-PGA2-S-glutathione conjugate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133768 GO:1903216 regulation of protein processing involved in protein targeting to mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903216 regulation of mitochondrial processing|regulation of mitochondrial protein processing during import Any process that modulates the frequency, rate or extent of protein processing involved in protein targeting to mitochondrion. GO:1903215 negative regulation of protein targeting to mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903215 down regulation of mitochondrial translocation|down-regulation of mitochondrial protein import|negative regulation of mitochondrial protein import|downregulation of mitochondrial translocation|inhibition of protein-mitochondrial targeting|down regulation of protein import into mitochondrion|down regulation of protein targeting to mitochondria|downregulation of protein import into mitochondrion|downregulation of mitochondrial protein import|negative regulation of mitochondrial translocation|downregulation of protein targeting to mitochondria|down-regulation of mitochondrial translocation|down-regulation of protein targeting to mitochondrion|down regulation of mitochondrial protein import|down regulation of protein-mitochondrial targeting|down-regulation of protein import into mitochondrion|negative regulation of protein import into mitochondrion|downregulation of protein-mitochondrial targeting|down-regulation of protein targeting to mitochondria|inhibition of mitochondrial protein import|negative regulation of protein targeting to mitochondria|downregulation of protein targeting to mitochondrion|inhibition of mitochondrial translocation|inhibition of protein import into mitochondrion|down regulation of protein targeting to mitochondrion|inhibition of protein targeting to mitochondrion|inhibition of protein targeting to mitochondria|negative regulation of protein-mitochondrial targeting|down-regulation of protein-mitochondrial targeting Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to mitochondrion. GO:1903214 regulation of protein targeting to mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903214 regulation of mitochondrial translocation|regulation of protein import into mitochondrion|regulation of protein targeting to mitochondria|regulation of mitochondrial protein import|regulation of protein-mitochondrial targeting Any process that modulates the frequency, rate or extent of protein targeting to mitochondrion. GO:1903213 protein localization to subtelomeric heterochromatin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903213 protein localisation in subtelomeric heterochromatin|protein localization in subtelomeric heterochromatin|protein localization to telomeric heterochromatin|protein localisation to telomeric heterochromatin|protein localisation to subtelomeric heterochromatin A process in which a protein is transported to, or maintained in, a location within a subtelomeric heterochromatin. GO:1903212 protein localization to mating-type region heterochromatin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903212 protein localisation to mating-type region heterochromatin|protein localisation in mating-type region heterochromatin|protein localization in mating-type region heterochromatin A process in which a protein is transported to, or maintained in, a location within a mating-type region heterochromatin. GO:0048059 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048059 GO:1903211 mitotic recombination involved in replication fork processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903211 mitotic recombination involved in replication fork restart|mitotic recombination involved in replication restart|mitotic recombination involved in collapsed replication fork processing|mitotic recombination involved in recovery from replication fork arrest|mitotic recombination involved in recovery from replication fork stalling Any mitotic recombination that is involved in replication fork processing. GO:0048058 compound eye corneal lens development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048058 The process whose specific outcome is the progression of the corneal lens in the compound eye over time, from its formation to the mature structure. The corneal lens is a chitinous extracellular secretion of the four underlying cone cells and the pigment cells. GO:1903221 regulation of mitotic recombination involved in replication fork processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903221 regulation of mitotic recombination involved in recovery from replication fork stalling|regulation of mitotic recombination involved in replication restart|regulation of mitotic recombination involved in collapsed replication fork processing|prevention of genomic instability induced by DNA replication fork arrest|regulation of mitotic recombination involved in replication fork restart|regulation of mitotic recombination involved in recovery from replication fork arrest Any process that modulates the frequency, rate or extent of mitotic recombination involved in replication fork processing. Regulation of mitotic recombination contributes to replication fork processing by preventing recombination between inappropriate homologous sequences. GO:1903220 positive regulation of malate dehydrogenase (decarboxylating) (NADP+) activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903220 up-regulation of NADP-specific malate dehydrogenase activity|up regulation of malate dehydrogenase (decarboxylating, NADP)|activation of 'malic' enzyme|activation of NADP-linked decarboxylating malic enzyme|upregulation of malate dehydrogenase (NADP, decarboxylating)|upregulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|positive regulation of 'malic' enzyme|up regulation of malate dehydrogenase (decarboxylating) (NADP+) activity|activation of malate dehydrogenase (decarboxylating) (NADP+) activity|activation of NADP-malic enzyme activity|up-regulation of NADP-malic enzyme activity|positive regulation of NADP-linked decarboxylating malic enzyme|up regulation of 'malic' enzyme|upregulation of NADP-specific malic enzyme|up regulation of NADP-linked decarboxylating malic enzyme|up-regulation of L-malate:NADP oxidoreductase activity|upregulation of NADP-specific malate dehydrogenase activity|upregulation of malate dehydrogenase (decarboxylating, NADP)|activation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|up-regulation of malate dehydrogenase (NADP, decarboxylating)|up-regulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|activation of malate dehydrogenase (NADP, decarboxylating)|up-regulation of NADP-specific malic enzyme|upregulation of 'malic' enzyme|positive regulation of NADP-malic enzyme activity|upregulation of L-malate:NADP oxidoreductase activity|upregulation of NADP-linked decarboxylating malic enzyme|up-regulation of malate dehydrogenase (decarboxylating) (NADP+) activity|up-regulation of malate dehydrogenase (decarboxylating, NADP)|up regulation of NADP-malic enzyme activity|activation of malate dehydrogenase (decarboxylating, NADP)|up regulation of NADP-specific malate dehydrogenase activity|activation of NADP-specific malate dehydrogenase activity|positive regulation of NADP-specific malate dehydrogenase activity|activation of NADP-specific malic enzyme|positive regulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|positive regulation of malate dehydrogenase (NADP, decarboxylating)|up regulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|up regulation of malate dehydrogenase (NADP, decarboxylating)|up-regulation of 'malic' enzyme|up-regulation of NADP-linked decarboxylating malic enzyme|upregulation of malate dehydrogenase (decarboxylating) (NADP+) activity|positive regulation of NADP-specific malic enzyme|up regulation of L-malate:NADP oxidoreductase activity|activation of L-malate:NADP oxidoreductase activity|up regulation of NADP-specific malic enzyme|upregulation of NADP-malic enzyme activity|positive regulation of L-malate:NADP oxidoreductase activity|positive regulation of malate dehydrogenase (decarboxylating, NADP) Any process that activates or increases the frequency, rate or extent of malate dehydrogenase (decarboxylating) (NADP+) activity. GO:0048060 negative gravitaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048060 negative taxis in response to gravity|negative gravitactic behavior|negative geotactic behaviour|negative taxis in response to gravitytaxis in response to gravitational stimulus|negative geotactic behavior|negative gravitactic behaviour The directed movement of a motile cell or organism away from the source of gravity. CHEBI:38393 octadeca-9,11-dienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38393 CHEBI:77979 aclacinomycin T zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77979 CHEBI:77978 2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77978 CHEBI:77977 noreugenin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77977 CHEBI:77976 versicolorin A(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77976 CHEBI:63330 sodium-dependent Pi-transporter inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63330 CHEBI:87300 2-O-(alpha-D-glucosyl)-sn-glycerol 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87300 CHEBI:63332 EC 3.1.3.1 (alkaline phosphatase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63332 CHEBI:63331 9(R)-HPODE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63331 CHEBI:87305 trans-feruloyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87305 CHEBI:63338 deoxy sugar derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63338 CHEBI:87306 (7R)-6-deoxy-D-manno-oct-7-ulosuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87306 CHEBI:63339 deoxy oligosaccharide derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63339 CHEBI:77971 raising agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77971 CHEBI:77970 food thickening agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77970 CHEBI:77975 (2S,3S)-versiconal hemiacetal acetate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77975 CHEBI:77974 food packaging gas biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77974 CHEBI:77989 luteolin 7-O-[(beta-D-glucosiduronate)-(1->2)-(beta-D-glucosiduronate)](3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77989 CHEBI:77988 methyl aklanonate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77988 CHEBI:77987 aklanonate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77987 CHEBI:63340 deoxyhexose derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63340 CHEBI:63349 trideoxyhexose derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63349 CHEBI:63347 dideoxyhexose derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63347 CHEBI:63346 deoxymannose derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63346 CHEBI:77982 tetracenomycin F2(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77982 PR:000001315 frizzled-like G-protein coupled receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001315 class F G-protein coupled receptor|fam:frizzled A G-protein coupled receptor with core architecture consisting of an Fz domain (Pfam:PF01392), also known as Frizzled CRD (cysteine rich domain), followed by a Frizzled/Smoothened family membrane region (Pfam:PF01534), which includes 7 transmembrane helices, and a cytoplasmic domain containing the motif Lys-Thr-x-x-x-Trp. They generally function as cell-surface receptors for Wnts. CHEBI:77981 vancomycin aglycone(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77981 CHEBI:77980 aclacinomycin A zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77980 PR:000001317 interleukin-7 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001317 IL7|IL-7 A protein that is a translation product of the human IL7 gene or a 1:1 ortholog thereof. CHEBI:77985 aclacinomycin Y zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77985 CHEBI:77984 quercetin 3,3',7-trissulfate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77984 CHEBI:77983 1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate(13-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77983 CHEBI:77999 1(3)-O-(alk-1-enyl)-2-acylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77999 CHEBI:77998 1(3)-O-(alk-1-enyl)-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77998 CHEBI:63352 deoxyaldohexose derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63352 CHEBI:63351 deoxyketopentose derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63351 CHEBI:63350 deoxyketohexose derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63350 CHEBI:63355 deoxypentose derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63355 CHEBI:63353 disaccharide derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63353 CHEBI:77992 calycosin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77992 CHEBI:77991 aclacinomycin N zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77991 CHEBI:77990 tetracenomycin D3(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77990 CHEBI:77997 1(3)-O-alkylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77997 CHEBI:77996 N-oleoylsphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77996 CHEBI:77994 aklaviketone(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77994 CHEBI:143197 culmorin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_143197 CHEBI:63361 glycosylglucose derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63361 CHEBI:63360 glycosylgalactose derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63360 CHEBI:63367 monosaccharide derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63367 CHEBI:87313 8-amino-3,8-dideoxy-alpha-D-manno-oct-2-ulosonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87313 CHEBI:63369 D-aldose derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63369 CHEBI:63368 aldose derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63368 GO:0000089 mitotic metaphase biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0000089 The cell cycle phase, following prophase, during which chromosomes become aligned on the equatorial plate of the cell as part of a mitotic cell cycle. GO:0000088 mitotic prophase biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0000088 The cell cycle phase which is the first stage of M phase of mitosis and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell. GO:0000087 mitotic M phase biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0000087 M-phase of mitotic cell cycle|M phase of mitotic cell cycle A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a mitotic cell cycle. GO:0000082 G1/S transition of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000082 The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated. CHEBI:63373 aldopentose derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63373 GO:0000081 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000081 GO:0000080 mitotic G1 phase biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0000080 G1 phase of mitotic cell cycle The cell cycle 'gap' phase which is the interval between the completion of DNA segregation by mitosis and the beginning of DNA synthesis. GO:0000086 G2/M transition of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000086 mitotic G2/M transition The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex. CHEBI:63378 anhydro sugar derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63378 GO:0000085 mitotic G2 phase biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0000085 G2 phase of mitotic cell cycle The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation by mitosis. GO:0000084 mitotic S phase biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0000084 S phase of mitotic cell cycle|S-phase of mitotic cell cycle The cell cycle phase, following G1, during which DNA synthesis takes place as part of a mitotic cell cycle. GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000083 Any process that regulates transcription such that the target genes are involved in the transition between G1 and S phase of the mitotic cell cycle. CHEBI:63379 anhydrohexose derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63379 PR:000001348 erythrocyte membrane protein Rh biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001348 A protein that is a stand alone version of the Ammonium Transporter Family domain in vertebrates. This protein is related to the ammonium transporters in fungi and bacteria. In mammals, this protein defines the Rh blood group antigens. PR:000001349 fibroblast growth factor receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001349 A protein with an extracellular region containing three copies of the Immunoglobulin domain (Pfam:PF00047), a single transmembrane region, and an intracellular region containing a Protein tyrosine kinase domain (Pfam:PF07714). Its active form binds fibroblast growth factor (FGF). FGFs and its receptor comprise a signaling system that is conserved throughout metazoan evolution. GO:0000099 sulfur amino acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000099 sulfur amino acid transporter activity|sulphur amino acid transmembrane transporter activity|sulphur amino acid transporter activity Enables the transfer of sulfur amino acids from one side of a membrane to the other. Sulphur amino acids contain sulfur in the form of cystine, methionine or their derivatives. GO:0000098 sulfur amino acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000098 sulfur amino acid breakdown|sulphur amino acid catabolic process|sulphur amino acid catabolism|sulfur amino acid degradation|sulfur amino acid catabolism The chemical reactions and pathways resulting in the breakdown of amino acids containing sulfur, comprising cysteine, methionine and selenocysteine. CHEBI:63385 hexose derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63385 GO:0000093 mitotic telophase biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0000093 The cell cycle phase which follows anaphase during M phase of mitosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts. CHEBI:63384 ketoheptose derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63384 GO:0000092 mitotic anaphase B biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0000092 The cell cycle phase during which the polar microtubules elongate and the two poles of the spindle move farther apart as part of mitosis. GO:0000091 mitotic anaphase A biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0000091 The cell cycle phase during which the kinetochore microtubules shorten as chromosomes move toward the spindle poles as part of mitosis. CHEBI:63383 heptose derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63383 CHEBI:87331 17beta-hydroxy-5beta-androst-1-en-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87331 GO:0000090 mitotic anaphase biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0000090 The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of a mitotic cell cycle. GO:0000097 sulfur amino acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000097 sulfur amino acid biosynthesis|sulfur amino acid anabolism|sulfur amino acid synthesis|sulfur amino acid formation|sulphur amino acid biosynthesis|sulphur amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of amino acids containing sulfur, comprising cysteine, methionine and selenocysteine. CHEBI:63389 UDP-4-amino-4,6-dideoxy-L-N-acetyl-beta-L-altrosamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63389 CHEBI:87333 17beta-hydroxy-5beta-estran-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87333 GO:0000096 sulfur amino acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000096 sulfur amino acid metabolism|sulphur amino acid metabolic process|sulphur amino acid metabolism The chemical reactions and pathways involving amino acids containing sulfur, comprising cysteine, homocysteine, methionine and selenocysteine. GO:0000095 S-adenosyl-L-methionine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000095 Reactome:R-HSA-8855062 SAM transmembrane transporter activity|S-adenosylmethionine transmembrane transporter activity|S-adenosyl methionine permease activity|S-adenosylmethionine permease activity|S-adenosyl methionine transporter activity|S-adenosylmethionine transporter activity Enables the transfer of S-adenosylmethionine from one side of a membrane to the other. S-adenosylmethionine is S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism. GO:0000094 obsolete septin assembly and septum formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000094 septin assembly and septum formation OBSOLETE. (Was not defined before being made obsolete). PR:000001353 granulocyte colony-stimulating factor receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001353 G-CSF-R|CSF3R|CD114|G-CSF receptor|GCSFR|Csfgr A protein that is a translation product of the human CSF3R gene or a 1:1 ortholog thereof. The active receptor is a homodimer which can bind G-CSF and transduce G-CSF-triggered growth signals into cells. Its extracellular domain contains a sequence of about 200 amino acids which can be found in various cytokine receptors. In addition, it contains an immunoglobulin-like domain and three fibronectin type III domains. CHEBI:87339 lipid A 1-(2-aminoethyl diphosphate) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87339 PR:000001357 intercellular adhesion molecule 1/3 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001357 ICAM A protein with a core domain architecture consisting of an Intercellular adhesion molecule (ICAM), N-terminal domain (Pfam:PF03921), a type of Ig-like domain, and four copies of the Immunoglobulin domain (Pfam:PF00047), most of which are not detected by Pfam. GO:0000068 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000068 GO:0000067 obsolete DNA replication and chromosome cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000067 DNA replication and chromosome cycle OBSOLETE. (Was not defined before being made obsolete). GO:0000066 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000066 GO:0000065 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000065 CHEBI:63391 ketohexose derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63391 PR:000015975 sperm motility kinase Tcr mutant form biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000015975 responder protein Smok-Tcr|Tcr|dominant negative form of Smok|Smoktcr|SmokTcr A protein that is a translation product of the mouse Smoktcr gene or a 1:1 ortholog thereof. GO:0000069 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000069 GO:0000060 obsolete protein import into nucleus, translocation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000060 protein translocation during protein import into nucleus|protein import into cell nucleus, translocation|protein-nucleus import, translocation|protein transport from cytoplasm to nucleus, translocation|protein translocation during protein transport from cytoplasm to nucleus|protein translocation during protein-nucleus import OBSOLETE. A protein transport process that contributes to protein import into the nucleus, and that results in the vectorial transfer of a cargo-carrier protein complex through the nuclear pore complex from the cytoplasmic side to the nucleoplasmic side of the nuclear envelope. CHEBI:87362 pentyl acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87362 CHEBI:63394 ketoaldonic acid derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63394 GO:0000064 L-ornithine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000064 Reactome:R-HSA-70634 histidine/arginine/lysine/ornithine porter activity|L-ornithine transporter activity Enables the transfer of L-ornithine from one side of a membrane to the other. L-ornithine is 2,5-diaminopentanoic acid. GO:0000063 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000063 GO:0000062 fatty-acyl-CoA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000062 fatty-acyl-coenzyme A binding|fatty-acyl binding Interacting selectively and non-covalently with a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty acyl group. GO:0000061 obsolete protein import into nucleus, substrate release biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000061 protein substrate release during protein transport from cytoplasm to nucleus|protein-nucleus import, substrate release|protein transport from cytoplasm to nucleus, substrate release|protein substrate release during protein import into nucleus|protein substrate release during protein-nucleus import|protein import into cell nucleus, substrate release OBSOLETE. A protein complex disassembly process that contributes to protein import into the nucleus, and that results in the dissociation of the cargo protein and the carrier (such as an importin alpha/beta heterodimer) from each other and from the nuclear pore complex. PR:000001327 cadherin biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001327 A protein that has a core domain structure of signal sequence, propeptide, five Cadherin domains (Pfam:PF00028), a transmembrane region, and a Cadherin cytoplasmic region (Pfam:PF01049). Cadherins function as adhesion molecules that mediate Ca2+-dependent cell-cell adhesion in solid tissues. GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000079 regulation of cyclin-dependent protein kinase activity|regulation of CDK activity Any process that modulates the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity. GO:0000078 obsolete cytokinesis after mitosis checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000078 cell shape checkpoint|cell morphogenesis checkpoint OBSOLETE. A mitotic cell cycle checkpoint that detects whether chromosome segregation is complete and negatively regulates cytokinesis following mitosis. GO:0000077 DNA damage checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000077 Wikipedia:Postreplication_checkpoint|Wikipedia:DNA_damage_checkpoint DNA damage response, signal transduction resulting in cell cycle arrest A cell cycle checkpoint that regulates progression through the cell cycle in response to DNA damage. A DNA damage checkpoint may blocks cell cycle progression (in G1, G2 or metaphase) or slow the rate at which S phase proceeds. GO:0000076 DNA replication checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000076 A cell cycle checkpoint that prevents the initiation of nuclear division until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome. GO:0000071 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000071 CHEBI:167106 androstane conjugate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_167106 GO:0000070 mitotic sister chromatid segregation biolink:BiologicalProcess go-plus goslim_pombe http://purl.obolibrary.org/obo/GO_0000070 mitotic sister-chromatid adhesion release|mitotic chromosome segregation The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets. CHEBI:167105 cholestane conjugate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_167105 CHEBI:167108 pregnane conjugate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_167108 CHEBI:167107 estrane conjugate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_167107 GO:0000075 cell cycle checkpoint biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0000075 Wikipedia:Cell_cycle_checkpoint G1/S transition checkpoint|G2/M checkpoint|G2/M transition checkpoint|G1/S checkpoint A cell cycle process that controls cell cycle progression by monitoring the integrity of specific cell cycle events. A cell cycle checkpoint begins with detection of deficiencies or defects and ends with signal transduction. CHEBI:87356 (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E)-decaprenyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87356 GO:0000074 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000074 GO:0000073 initial mitotic spindle pole body separation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000073 The release of duplicated mitotic spindle pole bodies (SPBs) that begins with the nucleation of microtubules from each SPB within the nucleus, leading to V-shaped spindle microtubules. Interpolar microtubules that elongate from each pole are interconnected, forming overlapping microtubules. Capturing and antiparallel sliding apart of microtubules promotes the initial separation of the SPB. CHEBI:167104 seco-cholestane conjugate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_167104 GO:0000072 obsolete M phase specific microtubule process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000072 M-phase specific microtubule process|M phase specific microtubule process OBSOLETE. A microtubule-based process that occurs only during M phase of the cell cycle. CHEBI:167109 acyl sugars biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_167109 PR:000001335 class 2 cytokine, IL-10 type biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001335 A protein with a core domain architecture consisting of an N-terminal Interleukin 10 (Pfam:PF00726) domain. CHEBI:28968 N'-phosphoguanidinoethyl methyl hydrogen phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28968 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097199 initiator caspase activity|apical caspase activity|activator caspase activity|cysteine-type endopeptidase activity involved in apoptotic signalling pathway Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic signaling pathway. CHEBI:28969 N,N-dimethyltryptamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28969 GO:0097196 Shu complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097196 A protein complex involved in error-free DNA post-replication repair (PRR). In Saccharomyces cerevisiae the complex contains Csm2p, Psy3p, Shu1p, and Shu2p. GO:0097195 pilomotor reflex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097195 horripilation|goosebump reflex|piloerection The reflex process in which the arrectores pilorum (hair follicle) muscles contract and cause the hair to stand erect. CHEBI:28963 amino sugar biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28963 GO:0097198 histone H3-K36 trimethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097198 The modification of histone H3 by addition of three methyl groups to lysine at position 36 of the histone. CHEBI:28966 chlorophyll biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28966 GO:0097197 tetraspanin-enriched microdomain biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097197 membrane tetraspanin-enriched microdomain|TEM A pre-organized unit composed either of adhesion molecules (mainly integrins and members of the Ig superfamily), signaling receptors and/or enzyme-enriched plasma membrane domains that compartmentalizes cellular processes. Tetraspanin-enriched microdomains might be specially suited for the regulation of avidity of adhesion receptors and the compartmentalization of enzymatic activities. CHEBI:28965 dicarboxylic acid dianion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28965 GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097192 extrinsic apoptotic signalling pathway in absence of ligand|dependence receptor signaling pathway|extrinsic apoptosis in absence of ligand A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with withdrawal of a ligand from a cell surface receptor, and ends when the execution phase of apoptosis is triggered. GO:0097191 extrinsic apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097191 extrinsic apoptotic signaling pathway in presence of ligand|extrinsic apoptosis|death receptor-mediated apoptosis|extrinsic apoptotic signalling pathway|extrinsic apoptotic pathway A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with either a ligand binding to a cell surface receptor, or a ligand being withdrawn from a cell surface receptor (e.g. in the case of signaling by dependence receptors), and ends when the execution phase of apoptosis is triggered. GO:0097194 execution phase of apoptosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097194 apoptosis|execution phase of apoptotic process A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. UBERON:0035322 right common iliac artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035322 trunk of right common iliac arterial tree GO:0097193 intrinsic apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097193 mitochondrial-mediated apoptotic pathway|intrinsic apoptotic signalling pathway|induction of apoptosis by intracellular signals|intrinsic apoptosis|intrinsic apoptotic pathway A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway starts with reception of an intracellular signal (e.g. DNA damage, endoplasmic reticulum stress, oxidative stress etc.), and ends when the execution phase of apoptosis is triggered. The intrinsic apoptotic signaling pathway is crucially regulated by permeabilization of the mitochondrial outer membrane (MOMP). CHEBI:28961 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28961 GO:0097190 apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097190 apoptotic signalling pathway|induction of apoptosis by extracellular signals A series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered. UBERON:0035316 prostatic capsule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035316 capsule of prostate gland|capsule of prostate The membrane the surrounds the prostate gland. CHEBI:14314 D-glucose 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_14314 CHEBI:77901 anthocyanidin 3-O-[2-O-(4-coumaroyl)-alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] 5-O-beta-D-glucoside betaine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77901 CHEBI:77900 (1'S,5'S)-5'-hydroxyaverantin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77900 CHEBI:77906 minocycline zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77906 CHEBI:28975 2,5-dichloro-2,5-cyclohexadiene-1,4-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28975 CHEBI:77904 norsolorinic acid anthrone(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77904 CHEBI:28977 2-hydroxy-3-carboxylato-6-oxo-7-methylocta-2,4-dienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28977 CHEBI:28976 carbonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28976 CHEBI:28972 (R)-propane-1,2-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28972 CHEBI:77907 hydroxyversicolorone(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77907 GO:0097178 ruffle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097178 membrane ruffling|membrane ruffle formation The aggregation, arrangement and bonding together of a set of components to form a ruffle, a projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork. The formation of ruffles (also called membrane ruffling) is thought to be controlled by a group of enzymes known as Rho GTPases, specifically RhoA, Rac1 and cdc42. CHEBI:28946 theobromine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28946 CHEBI:77913 9(R)-HPETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77913 GO:0097177 mitochondrial ribosome binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097177 Interacting selectively and non-covalently with any part of a mitochondrial ribosome, a ribosome found in the mitochondrion of a eukaryotic cell. CHEBI:28948 gramine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28948 GO:0097179 protease inhibitor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097179 peptidase inhibitor complex A heterodimeric protein complex that contains a protease inhibitor and a protease; formation of the complex inhibits protease activity. CHEBI:28947 (5-oxo-2-sulfo-2,5-dihydrofuran-2-yl)acetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28947 GO:0097174 1,6-anhydro-N-acetyl-beta-muramic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097174 1,6-anhydro-N-acetylmuramic acid metabolic process|1,6-anhydro-N-acetyl-beta-muramate metabolic process|1,6-anhydro-N-acetyl-beta-muramic acid metabolism|1,6-anhydro-N-acetyl-beta-muramate metabolism|1,6-anhydro-N-acetylmuramic acid metabolism The chemical reactions and pathways involving 1,6-anhydro-N-acetyl-beta-muramic acid, the 1,6-anhydro-derivative of N-acetyl-beta-muramic acid. CHEBI:28942 CDP-alpha-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28942 GO:0097173 N-acetylmuramic acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097173 N-acetylmuramate breakdown|N-acetylmuramic acid catabolism|N-acetylmuramate catabolic process|N-acetylmuramic acid degradation|N-acetylmuramic acid breakdown|N-acetylmuramate catabolism|N-acetylmuramate degradation The chemical reactions and pathways resulting in the breakdown of N-acetylmuramic acid (MurNAc), a monosaccharide derivative of N-acetylglucosamine. CHEBI:28941 docosanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28941 GO:0097176 epoxide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097176 epoxide metabolism The chemical reactions and pathways involving epoxides, compounds in which an oxygen atom is directly attached to two adjacent or non-adjacent carbon atoms of a carbon chain or ring system; thus cyclic ethers. CHEBI:28944 N-acetyl-7-O-acetylneuraminate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28944 CHEBI:77914 3-methylbut-1-ene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77914 GO:0097175 1,6-anhydro-N-acetyl-beta-muramic acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097175 1,6-anhydro-N-acetylmuramate catabolism|1,6-anhydro-N-acetyl-beta-muramic acid catabolism|1,6-anhydro-N-acetylmuramic acid degradation|1,6-anhydro-N-acetyl-beta-muramate degradation|1,6-anhydro-N-acetylmuramic acid breakdown|1,6-anhydro-N-acetyl-beta-muramate breakdown|1,6-anhydro-N-acetylmuramic acid catabolic process|1,6-anhydro-N-acetyl-beta-muramate catabolic process|1,6-anhydro-N-acetyl-beta-muramate catabolism|1,6-anhydro-N-acetylmuramic acid catabolism|1,6-anhydro-N-acetyl-beta-muramic acid degradation|1,6-anhydro-N-acetylmuramate degradation|1,6-anhydro-N-acetyl-beta-muramic acid breakdown|1,6-anhydro-N-acetylmuramate breakdown|1,6-anhydro-N-acetylmuramate catabolic process The chemical reactions and pathways resulting in the breakdown of 1,6-anhydro-N-acetylmuramic acid, the 1,6-anhydro-derivative of N-acetyl-beta-muramic acid. CHEBI:28943 N-acylsphingosine 1-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28943 GO:0097170 ADP-L-glycero-beta-D-manno-heptose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097170 ADP-L-glycero-beta-D-manno-heptose metabolism The chemical reactions and pathways involving ADP-L-glycero-beta-D-manno-heptose, an ADP-L-glycero-D-manno-heptose having beta-configuration at the anomeric centre of the heptose. ADP-L-glycero-beta-D-manno-heptose (also called ADP-L-beta-D-heptose or ADP-L-glycero-D-manno-heptose) is a nucleotide-sugar precursor of the inner core lipopolysaccharide (LPS) from D-glycero-beta-D-manno-heptose 7-phosphate. GO:0097172 N-acetylmuramic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097172 N-acetylmuramic acid metabolism|N-acetylmuramate metabolism|N-acetylmuramate metabolic process The chemical reactions and pathways involving N-acetylmuramic acid (MurNAc), a monosaccharide derivative of N-acetylglucosamine. CHEBI:77919 (7R)-hydroxy-(5S,6S)-epoxy-(8Z,11Z,14Z)-icosatrienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77919 CHEBI:28940 calciol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28940 GO:0097171 ADP-L-glycero-beta-D-manno-heptose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097171 ADP-L-glycero-beta-D-manno-heptose formation|ADP-L-glycero-beta-D-manno-heptose biosynthesis|ADP-L-glycero-beta-D-manno-heptose anabolism|ADP-L-glycero-beta-D-manno-heptose synthesis The chemical reactions and pathways resulting in the formation of ADP-L-glycero-beta-D-manno-heptose, an ADP-L-glycero-D-manno-heptose having beta-configuration at the anomeric centre of the heptose. ADP-L-glycero-beta-D-manno-heptose (also called ADP-L-beta-D-heptose or ADP-L-glycero-D-manno-heptose) is a nucleotide-sugar precursor of the inner core lipopolysaccharide (LPS) from D-glycero-beta-D-manno-heptose 7-phosphate. UBERON:0011332 extrinsic tongue pre-muscle mass biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011332 CHEBI:14336 glycerol 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_14336 GO:0097189 apoptotic body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097189 apoptotic bleb|apoptotic vesicle A vesicle containing parts of a dying cell. Apoptotic bodies can be formed during the execution phase of the apoptotic process, when the cell's cytoskeleton breaks up and causes the membrane to bulge outward. These bulges may separate from the cell, taking a portion of cytoplasm with them, to become apoptotic bodies. These are then engulfed by phagocytic cells, and their components recycled. Apoptotic bodies may range in size from 0.8 to 5um. GO:0097188 dentin mineralization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097188 dentine mineralization The process in which calcium salts are deposited into the calcareous tooth structure known as dentin. CHEBI:28956 cobinamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28956 CHEBI:77922 isopentenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77922 GO:0097185 cellular response to azide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097185 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an azide stimulus. UBERON:0001997 olfactory epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001997 MOE|sensory olfactory epithelium|olfactory sensory epithelium|nasal sensory epithelium|nasal epithelium|nasal cavity olfactory epithelium|olfactory membrane|pseudostratified main olfactory epithelium|main olfactory epithelium A sensory epithelium inside the nasal cavity that is responsible for detecting odors[WP]. CHEBI:28952 5alpha-pregnane-3,20-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28952 CHEBI:77927 nonan-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77927 GO:0097184 response to azide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097184 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an azide stimulus. GO:0097187 dentinogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097187 dentine development|dentin development The process whose specific outcome is the formation of dentin, the mineralized tissue that constitutes the major bulk of teeth. Dentin may be one of three types: primary dentin, secondary dentin, and tertiary dentin. CHEBI:28955 2-methoxy-17beta-estradiol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28955 GO:0097186 amelogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097186 enamel development The process whose specific outcome is the formation of tooth enamel, occurring in two stages: secretory stage and maturation stage. GO:0097181 protein C inhibitor-coagulation factor V complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097181 protein C inhibitor-F5 complex|PCI-coagulation factor V complex|serpin A5-coagulation factor V complex|plasma serine protease inhibitor-coagulation factor V complex|SERPINA5-coagulation factor V complex A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and coagulation factor V (F5); formation of the complex inhibits the serine protease activity of coagulation factor V. GO:0097180 serine protease inhibitor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097180 serine-type endopeptidase inhibitor complex|serpin complex A heterodimeric protein complex that contains a serine protease inhibitor and a protease; formation of the complex inhibits serine protease activity. GO:0097183 protein C inhibitor-coagulation factor XI complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097183 PCI-coagulation factor XI complex|protein C inhibitor-F11 complex|SERPINA5-coagulation factor XI complex|plasma serine protease inhibitor-coagulation factor XI complex|serpin A5-coagulation factor XI complex A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and coagulation factor XI (F11); formation of the complex inhibits the serine protease activity of coagulation factor XI. CHEBI:28951 (9S,10S)-9,10-dihydrophenanthrene-9,10-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28951 GO:0097182 protein C inhibitor-coagulation factor Xa complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097182 serpin A5-coagulation factor Xa complex|PCI-coagulation factor Xa complex|SERPINA5-coagulation factor Xa complex|plasma serine protease inhibitor-coagulation factor Xa complex A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and coagulation factor Xa (F10); formation of the complex inhibits the serine protease activity of coagulation factor Xa. CHEBI:14321 glutamate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_14321 CHEBI:77935 cyanidin 3-O-beta-D-galactoside(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77935 CHEBI:77933 (S)-5'-oxoaverantin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77933 CHEBI:77932 tetracycline zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77932 CHEBI:77939 oroxylin A(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77939 CHEBI:77938 barbiturate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77938 CHEBI:28928 angelicin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28928 CHEBI:77931 cyanidin 3-O-{6-O-[6-O-(4-coumaroyl)-beta-D-glucosyl]-2-O-beta-D-xylosyl-beta-D-galactoside}(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77931 CHEBI:28927 sakuranetin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28927 CHEBI:28935 (E)-hexadec-2-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28935 CHEBI:77946 anthocyanidin 3-O-sophoroside betaine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77946 CHEBI:77945 anthocyanidin 3-O-beta-D-sambubioside betaine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77945 CHEBI:28934 vitamin D2 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28934 CHEBI:77944 anthocyanidin 5-O-beta-D-glucoside 3-O-beta-D-sambubioside betaine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77944 CHEBI:28937 (-)-abscisic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28937 CHEBI:77943 anthocyanidin 3-glucoside 5-[(6-O-4-hydroxycinnamoyl)glucoside] betaine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77943 CHEBI:28936 2-acyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28936 CHEBI:28931 3'-AMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28931 CHEBI:77948 isoliquiritigenin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77948 CHEBI:77947 (S)-versiconol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77947 CHEBI:63300 osmoregulated periplasmic glucan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63300 CHEBI:63305 dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63305 CHEBI:63304 dTDP-D-ravidosamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63304 CHEBI:63303 dTDP-3-dehydro-6-deoxy-alpha-D-galactose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63303 CHEBI:63302 dTDP-3-dehydro-6-deoxy-alpha-D-galactose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63302 CHEBI:63309 mycinamicin cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63309 CHEBI:63308 mycinamicin III(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63308 CHEBI:63307 10-deoxymethymycin(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63307 CHEBI:28939 N-acetyl-L-cysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28939 CHEBI:77941 EC 3.5.1.4 (amidase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77941 CHEBI:28938 ammonium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28938 CHEBI:28902 N-phenylhydroxylamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28902 CHEBI:77956 L-erythro-sphingosine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77956 CHEBI:28903 decan-1-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28903 UBERON:0011370 transverse process of atlas biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011370 A transverse process of vertebra that is part of a vertebral bone 1. UBERON_CORE:proximally_connected_to proximally connected to biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/uberon/core#proximally_connected_to proximally_connected_to x proximally_connected_to y iff the proximal part of x is connected to y. i.e. x connected_to y and x distal_to y. CHEBI:28900 N-alkylphthalic monoamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28900 CHEBI:63311 mycinamicin VI(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63311 CHEBI:63310 mycinamicin IV(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63310 CHEBI:63319 D-erythritol 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63319 CHEBI:28909 iprodione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28909 CHEBI:28905 prop-2-yn-1-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28905 CHEBI:77951 versicolorin B(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77951 CHEBI:28907 2,3-bisphosphoglyceric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28907 CHEBI:77950 (2S-3S)-versiconal hemiacetal(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77950 CHEBI:28913 (2E)-hexenal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28913 CHEBI:77968 humectant biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77968 CHEBI:77966 food stabiliser biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77966 CHEBI:28915 fosfomycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28915 CHEBI:77965 food anticaking agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77965 CHEBI:28914 1-acyl-sn-glycero-3-phospho-D-myo-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28914 CHEBI:28911 cob(III)alamin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28911 CHEBI:77969 food humectant biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77969 UBERON:0011363 cranial lymph vasculature biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011363 cranial lymphatics|set of cranial lymphatic vessels|cranial lymph vessels|cranial lymph vessel|set of lymphatic vessels of head A lymph vasculature that is part of a head. UBERON:0011362 cranial blood vasculature biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011362 set of blood vessels of head|cranial blood vessels|cranial blood vessel A blood vasculature that is part of a head. CHEBI:63323 9(R)-HPODE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63323 CHEBI:63322 (S)-2-hydroxy-3-oxo-4-(phosphonooxy)butanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63322 CHEBI:63325 (2R,3S)-2,4',7-trihydroxyisoflavanone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63325 CHEBI:63324 (8E,10R,12Z)-10-hydroperoxy-8,12-octadecadienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63324 CHEBI:63328 4'-hydroxyisoflavones biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63328 CHEBI:77964 anticaking agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77964 CHEBI:77962 food antioxidant biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77962 CHEBI:28919 estrone 3-O-(beta-D-glucuronide) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28919 CHEBI:28918 (R)-adrenaline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28918 CHEBI:77961 1,2-dioctanoyl-sn-glycerol 3-diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77961 GO:0000200 inactivation of MAPK activity involved in cell wall organization or biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000200 termination of MAPK activity during cell wall biogenesis|inactivation of MAPK activity involved in cell wall organization or biogenesis|cell wall biogenesis, termination of MAPK activity|inactivation of MAPK activity involved in cell wall integrity|cell wall biogenesis, inactivation of MAPK activity Any process that terminates the activity of the active enzyme MAP kinase in the context of cell wall organization or biogenesis. GO:0097112 gamma-aminobutyric acid receptor clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097112 GABA receptor clustering The receptor clustering process in which gamma-aminobutyric acid (GABA) receptors are localized to distinct domains in the cell membrane. GO:0048189 Lid2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0048189 A protein complex that is thought to be involved in regulation of chromatin remodeling. In Schizosaccharomyces the complex contains Lid1p, Ash2p, Ecm5p, Snt2p, and Sdc1p. GO:0048188 Set1C/COMPASS complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0048188 Set1C|Set1/COMPASS complex|COMPASS complex A conserved protein complex that catalyzes methylation of histone H3. In Saccharomyces the complex contains Shg1p, Sdc1p, Swd1p, Swd2p, Swd3p, Spp1p, Bre2p, and the trithorax-related Set1p; in mammals it contains the catalytic subunit (SETD1A or SETD1B), WDR5, WDR82, RBBP5, ASH2L/ASH2, CXXC1/CFP1, HCFC1 and DPY30. GO:0097111 endoplasmic reticulum-Golgi intermediate compartment organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097111 ERGIC organization|endoplasmic reticulum-Golgi intermediate compartment organisation|endoplasmic reticulum-Golgi intermediate compartment organization and biogenesis|ER-Golgi intermediate compartment organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER)-Golgi intermediate compartment. UBERON:0001946 inferior colliculus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001946 posterior corpus quadrigeminum|corpus bigeminalis caudalis|corpus bigeminum posterioris|inferior colliculi|caudal colliculus|colliculus caudalis|corpus quadrigeminum inferius|colliculus inferior|posterior colliculus Part of the midbrain tectum, consisting of paired predominantly gray matter elevations on the dorsal aspect of the midbrain, located caudal to the superior colliculus, dorsal to the periaqueductal gray of the cerebral aqueduct and rostral to the cerebellum. According to Neuronames, the inferior colliculus comprises the central, pericentral and external nucleus and two predominantly white matter structures, the brachium of the inferior colliculus and the commissure of the inferior colliculus (MM). GO:0097114 NMDA glutamate receptor clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097114 N-methyl-D-aspartate receptor clustering|NMDA receptor clustering The receptor clustering process in which N-methyl-D-aspartate (NMDA) receptors are localized to distinct domains in the cell membrane. GO:0048187 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048187 UBERON:0001949 gingival epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001949 gingiva epithelium|epithelium of gingiva|epithelial tissue of gingiva|gingiva epithelial tissue A stratified squamous epithelium consisting of a basal layer; it is keratinized or parakeratinized[BTO]. GO:0048186 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048186 GO:0097113 AMPA glutamate receptor clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097113 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|AMPA receptor clustering The glutamate receptor clustering process in which alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors are localized to distinct domains in the cell membrane. UBERON:0001948 regional part of spinal cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001948 spinal cord part A multi-tissue structure that is part of a spinal cord. UBERON:0001943 midbrain tegmentum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001943 MTg|tegmentum mesencephali|mesencephalic tegmentum|tegmentum of midbrain|tegmentum mesencephalicum|tegmentum Ventral part of the midbrain, separated from the hindbrain by the isthmus[ISBN:0471888893]. Subdivision of the midbrain lying anterior to the tectum and posterior to the substantia nigra and cerebral peduncle[FMA] The part of the midbrain extending from the substantia nigra to the cerebral aqueduct in a horizontal section of the midbrain. It forms the floor of the midbrain that surrounds the cerebral aqueduct[WP]. GO:0000204 obsolete activation of MAPKK during sporulation (sensu Saccharomyces) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000204 activation of MAPKK during sporulation (sensu Saccharomyces) OBSOLETE. Upregulation of a MAP kinase kinase in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930). GO:0048185 activin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048185 Interacting selectively and non-covalently with activin, a dimer of inhibin-beta subunits. GO:0000203 obsolete activation of MAPKKK during sporulation (sensu Saccharomyces) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000203 activation of MAPKKK during sporulation (sensu Saccharomyces) OBSOLETE. Upregulation of MAPKKK activity in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930). GO:0048184 obsolete follistatin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048184 follistatin binding OBSOLETE. Interacting selectively and non-covalently with the peptide hormone follistatin. GO:0000202 obsolete MAPKKK cascade during sporulation (sensu Saccharomyces) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000202 MAPKKK cascade during sporulation (sensu Saccharomyces) OBSOLETE. MAPKKK cascade involved in transduction of signal promoting sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930). UBERON:0001945 superior colliculus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001945 colliculus cranialis|colliculus bigeminalis oralis|tectum|tectal lobe|optic lobe|dorsal midbrain|strata (grisea et alba) colliculi superioris|colliculus superior|corpus quadrigeminum superius|optic tectum|layers of the superior colliculus|nates|optic tectum|anterior colliculus|cranial colliculus|lobus opticus|strata (grisea et alba) colliculi cranialis|colliculus rostralis|anterior corpus quadrigeminum|corpora bigemina|tectum opticum Part of the midbrain tecturm consisting of paired bodies that sit caudal to the thalamus and surround the pineal gland in the mesencephalon of vertebrate brains. It comprises the rostral aspect of the midbrain, posterior to the periaqueductal gray and adjacent superior the inferior colliculus. The inferior and superior colliculi are known collectively as the corpora quadrigemina (Latin, quadruplet bodies). It consists of several identified cellular layers and also comprises the brachium of the superior colliculus and commissure of supeior colliculus from Wikipedia.org and Neuronames (MM). GO:0048183 activin AB complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0048183 inhibin beta-B|inhibin beta-A A nonsteroidal regulator, composed of two covalently linked inhibin beta subunits (sometimes known as activin beta or activin/inhibin beta), inhibin beta-A and inhibin beta-B. GO:0097110 scaffold protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097110 Interacting selectively and non-covalently with a scaffold protein. Scaffold proteins are crucial regulators of many key signaling pathways. Although not strictly defined in function, they are known to interact and/or bind with multiple members of a signaling pathway, tethering them into complexes. GO:0000201 obsolete MAPK import into nucleus involved in cell wall organization or biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000201 cell wall biogenesis, MAPK import into nucleus|nuclear translocation of MAPK involved in cell wall biogenesis|nuclear translocation of MAPK involved in cell wall integrity|MAPK import into nucleus involved in cell wall integrity|MAPK import into nucleus involved in cell wall biogenesis|cell wall biogenesis, nuclear translocation of MAPK OBSOLETE. The directed movement of a MAP kinase to the nucleus that occurs in the context of cell wall organization or biogenesis. UBERON:0001944 pretectal region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001944 nuclei pretectales|regio pretectalis|area praetectalis|area pretectalis|nucleus praetectalis|pretectal nuclei|pretectal area|pretectum|praetectum Nuclear complex between dorsal thalamus and optic tectum whose nuclei receive afferents primarily from the retina and the optic tectum and are involved in modulating motor behavior in response to visual input. GO:0048182 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048182 GO:0014849 ureter smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014849 A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the ureter. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder. GO:0014848 urinary tract smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014848 A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary tract. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary tract consists of organs of the body that produce and discharge urine. These include the kidneys, ureters, bladder, and urethra. GO:0014847 proximal stomach smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014847 A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the proximal stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The proximal stomach, composed of the fundus and upper body, shows low frequency, sustained tonic contractions that are responsible for generating a basal pressure within the stomach. GO:1903589 positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903589 up regulation of blood vessel endothelial cell proliferation during sprouting angiogenesis|positive regulation of blood vessel endothelial cell proliferation during sprouting angiogenesis|up regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis|activation of blood vessel endothelial cell proliferation during sprouting angiogenesis|upregulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis|up-regulation of blood vessel endothelial cell proliferation during sprouting angiogenesis|up-regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis|upregulation of blood vessel endothelial cell proliferation during sprouting angiogenesis|activation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis Any process that activates or increases the frequency, rate or extent of blood vessel endothelial cell proliferation involved in sprouting angiogenesis. GO:0014846 esophagus smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014846 oesophagus smooth muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the esophagus. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The esophagus is the muscular membranous segment between the pharynx and the stomach in the upper gastrointestinal tract. GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903588 down regulation of blood vessel endothelial cell proliferation during sprouting angiogenesis|downregulation of blood vessel endothelial cell proliferation during sprouting angiogenesis|down-regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis|down-regulation of blood vessel endothelial cell proliferation during sprouting angiogenesis|downregulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis|negative regulation of blood vessel endothelial cell proliferation during sprouting angiogenesis|down regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis|inhibition of blood vessel endothelial cell proliferation involved in sprouting angiogenesis|inhibition of blood vessel endothelial cell proliferation during sprouting angiogenesis Any process that stops, prevents or reduces the frequency, rate or extent of blood vessel endothelial cell proliferation involved in sprouting angiogenesis. GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903587 regulation of blood vessel endothelial cell proliferation during sprouting angiogenesis Any process that modulates the frequency, rate or extent of blood vessel endothelial cell proliferation involved in sprouting angiogenesis. GO:1903586 positive regulation of histone deubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903586 up-regulation of histone deubiquitinylation|activation of histone deubiquitinylation|upregulation of histone deubiquitination|positive regulation of histone deubiquitylation|up regulation of histone deubiquitylation|positive regulation of histone deubiquitinylation|activation of histone deubiquitination|up regulation of histone deubiquitinylation|up-regulation of histone deubiquitination|upregulation of histone deubiquitylation|upregulation of histone deubiquitinylation|up regulation of histone deubiquitination|up-regulation of histone deubiquitylation|activation of histone deubiquitylation Any process that activates or increases the frequency, rate or extent of histone deubiquitination. GO:1903585 negative regulation of histone deubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903585 down regulation of histone deubiquitination|down-regulation of histone deubiquitylation|negative regulation of histone deubiquitylation|inhibition of histone deubiquitination|down-regulation of histone deubiquitinylation|negative regulation of histone deubiquitinylation|downregulation of histone deubiquitylation|down regulation of histone deubiquitylation|downregulation of histone deubiquitinylation|inhibition of histone deubiquitylation|down regulation of histone deubiquitinylation|down-regulation of histone deubiquitination|inhibition of histone deubiquitinylation|downregulation of histone deubiquitination Any process that stops, prevents or reduces the frequency, rate or extent of histone deubiquitination. GO:1903595 positive regulation of histamine secretion by mast cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903595 up-regulation of histamine secretion by mast cell|activation of histamine secretion by mast cell|up regulation of histamine secretion by mast cell|upregulation of histamine secretion by mast cell Any process that activates or increases the frequency, rate or extent of histamine secretion by mast cell. GO:0014841 skeletal muscle satellite cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014841 The multiplication or reproduction of satellite cells, resulting in the expansion of the cell population. Satellite cells are quiescent cells that are located between the basal lamina and the plasmalemma of the muscle fiber, which are the main contributors to postnatal muscle growth. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage. GO:1903594 negative regulation of histamine secretion by mast cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903594 down-regulation of histamine secretion by mast cell|downregulation of histamine secretion by mast cell|down regulation of histamine secretion by mast cell|inhibition of histamine secretion by mast cell Any process that stops, prevents or reduces the frequency, rate or extent of histamine secretion by mast cell. GO:1903593 regulation of histamine secretion by mast cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903593 Any process that modulates the frequency, rate or extent of histamine secretion by mast cell. GO:1903592 positive regulation of lysozyme activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903592 upregulation of lysozyme activity|activation of lysozyme g|upregulation of muramidase activity|up-regulation of PR1-lysozyme|up regulation of 1,4-N-acetylmuramidase activity|upregulation of peptidoglycan N-acetylmuramoylhydrolase activity|positive regulation of 1,4-N-acetylmuramidase activity|positive regulation of lysozyme g|activation of 1,4-N-acetylmuramidase activity|up-regulation of globulin G|up-regulation of L-7001|up regulation of lysozyme g|upregulation of N,O-diacetylmuramidase activity|up regulation of globulin G1|up regulation of mucopeptide glucohydrolase activity|upregulation of mucopeptide N-acetylmuramoylhydrolase activity|activation of PR1-lysozyme|positive regulation of mucopeptide glucohydrolase activity|activation of mucopeptide glucohydrolase activity|positive regulation of globulin G1|up regulation of lysozyme activity|activation of lysozyme activity|up regulation of muramidase activity|activation of L-7001|up-regulation of peptidoglycan N-acetylmuramoylhydrolase activity|activation of globulin G|activation of peptidoglycan N-acetylmuramoylhydrolase activity|positive regulation of muramidase activity|activation of muramidase activity|positive regulation of PR1-lysozyme|activation of globulin G1|up-regulation of 1,4-N-acetylmuramidase activity|up regulation of PR1-lysozyme|upregulation of lysozyme g|positive regulation of globulin G|up regulation of N,O-diacetylmuramidase activity|positive regulation of L-7001|up-regulation of mucopeptide N-acetylmuramoylhydrolase activity|activation of N,O-diacetylmuramidase activity|positive regulation of N,O-diacetylmuramidase activity|up regulation of L-7001|up regulation of globulin G|activation of mucopeptide N-acetylmuramoylhydrolase activity|up-regulation of globulin G1|up-regulation of mucopeptide glucohydrolase activity|up-regulation of lysozyme activity|positive regulation of peptidoglycan N-acetylmuramoylhydrolase activity|up regulation of peptidoglycan N-acetylmuramoylhydrolase activity|up-regulation of muramidase activity|upregulation of 1,4-N-acetylmuramidase activity|upregulation of PR1-lysozyme|up-regulation of lysozyme g|upregulation of L-7001|upregulation of globulin G|positive regulation of mucopeptide N-acetylmuramoylhydrolase activity|upregulation of mucopeptide glucohydrolase activity|upregulation of globulin G1|up-regulation of N,O-diacetylmuramidase activity|up regulation of mucopeptide N-acetylmuramoylhydrolase activity Any process that activates or increases the frequency, rate or extent of lysozyme activity. GO:1903591 negative regulation of lysozyme activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903591 down regulation of globulin G1|inhibition of globulin G|inhibition of L-7001|down regulation of mucopeptide glucohydrolase activity|down-regulation of lysozyme g|negative regulation of lysozyme g|downregulation of mucopeptide N-acetylmuramoylhydrolase activity|inhibition of peptidoglycan N-acetylmuramoylhydrolase activity|down regulation of lysozyme activity|down regulation of muramidase activity|downregulation of mucopeptide glucohydrolase activity|downregulation of globulin G1|down regulation of mucopeptide N-acetylmuramoylhydrolase activity|downregulation of lysozyme activity|inhibition of mucopeptide N-acetylmuramoylhydrolase activity|negative regulation of 1,4-N-acetylmuramidase activity|down-regulation of 1,4-N-acetylmuramidase activity|downregulation of muramidase activity|negative regulation of PR1-lysozyme|down-regulation of PR1-lysozyme|down regulation of N,O-diacetylmuramidase activity|downregulation of lysozyme g|down-regulation of globulin G|down-regulation of L-7001|negative regulation of globulin G|negative regulation of L-7001|down-regulation of mucopeptide glucohydrolase activity|negative regulation of globulin G1|negative regulation of mucopeptide glucohydrolase activity|down-regulation of globulin G1|downregulation of N,O-diacetylmuramidase activity|down regulation of lysozyme g|inhibition of 1,4-N-acetylmuramidase activity|down-regulation of lysozyme activity|negative regulation of muramidase activity|down-regulation of muramidase activity|down-regulation of peptidoglycan N-acetylmuramoylhydrolase activity|downregulation of PR1-lysozyme|negative regulation of peptidoglycan N-acetylmuramoylhydrolase activity|inhibition of mucopeptide glucohydrolase activity|inhibition of lysozyme g|downregulation of L-7001|downregulation of globulin G|inhibition of lysozyme activity|negative regulation of N,O-diacetylmuramidase activity|down-regulation of N,O-diacetylmuramidase activity|down regulation of PR1-lysozyme|down-regulation of mucopeptide N-acetylmuramoylhydrolase activity|negative regulation of mucopeptide N-acetylmuramoylhydrolase activity|inhibition of muramidase activity|down regulation of L-7001|down regulation of globulin G|inhibition of globulin G1|downregulation of peptidoglycan N-acetylmuramoylhydrolase activity|down regulation of 1,4-N-acetylmuramidase activity|inhibition of PR1-lysozyme|inhibition of N,O-diacetylmuramidase activity|down regulation of peptidoglycan N-acetylmuramoylhydrolase activity|downregulation of 1,4-N-acetylmuramidase activity Any process that stops, prevents or reduces the frequency, rate or extent of lysozyme activity. GO:0014845 stomach body smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014845 A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the body of stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The body of stomach is the part of the stomach that lies between the fundus above and the pyloric antrum below; its boundaries are poorly defined. GO:1903590 regulation of lysozyme activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903590 regulation of mucopeptide glucohydrolase activity|regulation of globulin G1|regulation of mucopeptide N-acetylmuramoylhydrolase activity|regulation of muramidase activity|regulation of lysozyme g|regulation of N,O-diacetylmuramidase activity|regulation of PR1-lysozyme|regulation of L-7001|regulation of globulin G|regulation of peptidoglycan N-acetylmuramoylhydrolase activity|regulation of 1,4-N-acetylmuramidase activity Any process that modulates the frequency, rate or extent of lysozyme activity. GO:0014844 myoblast proliferation involved in skeletal muscle regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014844 The multiplication or reproduction of myoblasts, resulting in the expansion of the cell population. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. GO:0014843 growth factor dependent regulation of skeletal muscle satellite cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014843 Any process that modulates the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta. GO:0014842 regulation of skeletal muscle satellite cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014842 Any process that modulates the frequency, rate or extent of skeletal muscle satellite cell proliferation. GO:0048192 obsolete peptide antigen stabilization activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048192 peptide antigen stabilization activity OBSOLETE. Strengthening of a bond with a peptide antigen; a fragment of a foreign protein derived by proteolysis within the cell. UBERON:0001950 neocortex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001950 neocortex (isocortex)|iso-cortex|nucleus hypoglossalis|nonolfactory cortex|homotypical cortex|neopallium|neopallial cortex|homogenetic cortex|isocortex|cerebral neocortex|isocortex (sensu lato) An area of cerebral cortex defined on the basis of cytoarchitecture that have six layers. Starting from the cortical surface the layers are: molecular layer (I), external granular layer (II), external pyramidal layer (III), internal granular layer (IV), internal pyramidal layer (V), and multiform layer (VI). Neocortex is most prominent in the frontal lobe, the parietal lobe, the temporal lobe and the occipital lobe, less so in the cingulate gyrus, the parahippocampal gyrus and the insula. It is composed of two subdivisions: true isocortex and proisocortex (Carpenter-83)(NN) GO:0000208 obsolete MAPK import into nucleus involved in osmosensory signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000208 MAPK import into nucleus involved in osmosensory signalling pathway|osmolarity sensing, MAPK import into nucleus|osmolarity sensing, nuclear translocation of MAPK|nuclear translocation of MAPK during osmolarity sensing|MAPK import into nucleus during osmolarity sensing|nuclear translocation of MAPK involved in osmosensory signalling pathway|nuclear translocation of MAPK involved in osmosensory signaling pathway OBSOLETE. The directed movement of a MAP kinase to the nucleus during osmolarity sensing. GO:0000207 obsolete nuclear translocation of MAPK during sporulation (sensu Saccharomyces) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000207 nuclear translocation of MAPK during sporulation (sensu Saccharomyces) OBSOLETE. Movement of a MAP kinase to the nucleus in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930). GO:0097119 postsynaptic density protein 95 clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097119 PSD-95 clustering|post-synaptic density protein 95 clustering|Dlg4 clustering The clustering process in which postsynaptic density protein 95 (PSD-95) molecules are localized to distinct domains in the cell membrane. PSD-95 is mostly located in the post synaptic density of neurons, and is involved in anchoring synaptic proteins. GO:0048191 obsolete peptide stabilization activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048191 peptide stabilization activity OBSOLETE. Strengthening of a bond between peptides. Peptides are compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. UBERON_CORE:transitively_connected_to transitively_connected to biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/uberon/core#transitively_connected_to transitively_connected_to GO:0048190 wing disc dorsal/ventral pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048190 wing disc dorsal-ventral pattern formation|wing disc dorsoventral pattern formation The establishment, maintenance and elaboration of the dorsal/ventral axis of the wing disc, a precursor to the adult wing. GO:0000206 obsolete inactivation of MAPK during sporulation (sensu Saccharomyces) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000206 inactivation of MAPK during sporulation (sensu Saccharomyces) OBSOLETE. Downregulation of MAP kinase activity in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930). GO:0000205 obsolete activation of MAPK during sporulation (sensu Saccharomyces) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000205 activation of MAPK during sporulation (sensu Saccharomyces) OBSOLETE. Upregulation of MAP kinase activity in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930). UBERON:0001951 epithelium of nasopharynx biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001951 rhinopharynx epithelium|nasal part of pharynx epithelium|nasopharynx epithelium|epithelial tissue of rhinopharynx|epithelial tissue of nasopharynx|epithelium of nasal part of pharynx|epithelium of rhinopharynx|epithelial tissue of nasal part of pharynx|nasopharynx epithelial tissue|nasal part of pharynx epithelial tissue|rhinopharynx epithelial tissue|nasopharyngeal epithelium An epithelium that is part of a nasopharynx [Automatically generated definition]. GO:0097116 gephyrin clustering involved in postsynaptic density assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097116 Geph clustering The clustering process in which gephyrin molecules are localized to distinct domains in the postsynaptic density as part of postsynaptic density assembly. Gephyrin is a component of the postsynaptic protein network of inhibitory synapses. GO:0097115 neurexin clustering involved in presynaptic membrane assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097115 presynaptic neurexin clustering|neurexin clustering|Nrxn clustering The receptor clustering process involved in assembly of the presynaptic membrane in which neurexins are localized to distinct domains in the cell membrane. Neurexins are synaptic cell surface proteins which act as cell recognition molecules at nerve terminals. GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097118 Nlgn clustering|postsynaptic neuroligin clustering|neuroligin clustering The receptor clustering process involved in assembly of the postsynaptic membrane in which neuroligins are localized to distinct domains in the cell membrane. Neuroligins are neuronal cell surface proteins on the postsynaptic membrane that mediate synapse formation between neurons. GO:0000209 protein polyubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000209 polyubiquitin|protein polyubiquitylation|protein polyubiquitinylation Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain. GO:0097117 guanylate kinase-associated protein clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097117 GKAP clustering The clustering process in which guanylate kinase-associated proteins (GKAPs) are localized to distinct domains in the cell membrane. GKAP facilitates assembly of the post synaptic density of neurons. GO:0000211 obsolete protein degradation tagging activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000211 protein degradation tagging activity OBSOLETE. Covalent addition of polyubiquitin to another protein, targeting the tagged protein for destruction. GO:0097123 cyclin A1-CDK2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097123 A protein complex consisting of cyclin A1 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. GO:0048199 vesicle targeting, to, from or within Golgi biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048199 Golgi vesicle targeting|dictyosome vesicle targeting|vesicle targeting, to, from or within dictyosome The process in which vesicles are directed to specific destination membranes during transport to, from or within the Golgi apparatus; mediated by the addition of specific coat proteins, including COPI and COPII proteins and clathrin, to the membrane during vesicle formation. GO:0000210 NAD+ diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000210 RHEA:11800|EC:3.6.1.22|MetaCyc:NADPYROPHOSPHAT-RXN NAD pyrophosphatase activity|NAD diphosphatase activity|nicotinamide adenine dinucleotide pyrophosphatase activity|NAD(+) pyrophosphatase activity|NAD+ pyrophosphatase activity|NAD+ phosphohydrolase activity|NADH pyrophosphatase activity|NADP pyrophosphatase activity Catalysis of the reaction: NAD+ + H2O = AMP + NMN. GO:0097122 cyclin A2-CDK1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097122 A protein complex consisting of cyclin A2 and cyclin-dependent kinase 1 (CDK1). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. GO:0048198 Golgi vesicle bud deformation and release biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048198 Golgi-derived vesicle bud deformation and release|dictyosome vesicle bud deformation The process in which cytosolic coat proteins fit together in a basketlike convex framework to form a coated deformed region on the cytoplasmic surface of the membrane. The deformed region forms into a complete vesicle and is released. GO:0097125 cyclin B1-CDK1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097125 A protein complex consisting of cyclin B1 and cyclin-dependent kinase 1 (CDK1). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. GO:0048197 Golgi membrane coat protein complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048197 dictyosome membrane binding by cytosolic coat proteins|Golgi membrane bud coat oligomerisation|dictyosome membrane bud coat oligomerisation The aggregation, arrangement and bonding together of priming complexes to form a coat on a Golgi membrane. Priming complexes associate laterally and additional coat proteins are recruited from the cytosol to the forming coat. Cargo proteins diffuse into the budding site and become trapped by their interactions with the coat. GO:0097124 cyclin A2-CDK2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097124 A protein complex consisting of cyclin A2 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. GO:0000215 tRNA 2'-phosphotransferase activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0000215 RHEA:23324|MetaCyc:2.7.1.160-RXN|EC:2.7.1.160 2'-phosphotransferase activity|2'-phospho-[ligated tRNA]:NAD+ phosphotransferase activity|yeast 2'-phosphotransferase activity|2'-phospho-tRNA:NAD+ phosphotransferase activity|Tpt1|Tpt1p Catalysis of the reaction: 2'-phospho-[ligated tRNA] + NAD+ = mature tRNA + ADP ribose 1'',2''-phosphate + nicotinamide + H2O. This reaction is the transfer of the splice junction 2-phosphate from ligated tRNA to NAD+ to produce ADP-ribose 1'-2' cyclic phosphate. GO:0048196 obsolete plant extracellular matrix biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0048196 plant extracellular matrix|middle lamella-containing extracellular matrix OBSOLETE. The matrix external to the plant plasma membrane, composed of the cell wall and middle lamella. GO:0000214 tRNA-intron endonuclease complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000214 tRNA splicing endonuclease complex|SEN complex A protein complex that catalyzes the endonucleolytic cleavage of pre-tRNA, producing 5'-hydroxyl and 2',3'-cyclic phosphate termini, and specifically removing the intron. GO:0048195 Golgi membrane priming complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048195 formation of dictyosome membrane priming complex|formation of Golgi membrane priming complex The aggregation, arrangement and bonding together of a set of components to form a membrane priming complex. An incoming coat component recognizes both GTPase and a membrane protein to form the priming complex. GO:0000213 tRNA-intron endonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000213 MetaCyc:3.1.27.9-RXN|EC:3.1.27.9 splicing endonuclease activity|tRNA-splicing endonuclease activity|tRNA-intron endoribonuclease activity|transfer splicing endonuclease activity|transfer ribonucleate intron endoribonuclease activity|tRNA splicing endonuclease activity|tRNATRPintron endonuclease activity Catalysis of the endonucleolytic cleavage of pre-tRNA, producing 5'-hydroxyl and 2',3'-cyclic phosphate termini, and specifically removing the intron. GO:0048194 Golgi vesicle budding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048194 dictyosome vesicle budding|Golgi-derived vesicle budding The evagination of the Golgi membrane, resulting in formation of a vesicle. GO:0097121 cyclin A1-CDK1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097121 A protein complex consisting of cyclin A1 and cyclin-dependent kinase 1 (CDK1). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. GO:0048193 Golgi vesicle transport biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0048193 Golgi-derived vesicle transport The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles. GO:0097120 receptor localization to synapse biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097120 receptor localisation to synapse Any process in which a receptor is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. GO:0000212 meiotic spindle organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000212 meiotic spindle organization and biogenesis|meiotic spindle organisation|meiotic spindle stabilization|spindle organization during meiosis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a meiotic cell cycle. GO:0014859 negative regulation of skeletal muscle cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014859 Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle cell proliferation. GO:0014858 positive regulation of skeletal muscle cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014858 Any process that activates or increases the frequency, rate or extent of skeletal muscle cell proliferation. GO:0014857 regulation of skeletal muscle cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014857 Any process that modulates the frequency, rate or extent of skeletal muscle cell proliferation. GO:1903599 positive regulation of autophagy of mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903599 up regulation of mitochondrion degradation|activation of mitochondrion degradation|up-regulation of mitophagy|upregulation of mitophagy|up-regulation of mitochondrion degradation|up regulation of mitophagy|upregulation of mitochondrion degradation|positive regulation of mitochondrial degradation|activation of mitophagy Any process that activates or increases the frequency, rate or extent of mitochondrion degradation by autophagy. GO:1903598 positive regulation of gap junction assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903598 up-regulation of gap junction assembly|upregulation of gap junction assembly|up regulation of gap junction assembly|activation of gap junction assembly Any process that activates or increases the frequency, rate or extent of gap junction assembly. GO:1903597 negative regulation of gap junction assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903597 inhibition of gap junction assembly|down regulation of gap junction assembly|downregulation of gap junction assembly|down-regulation of gap junction assembly Any process that stops, prevents or reduces the frequency, rate or extent of gap junction assembly. GO:1903596 regulation of gap junction assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903596 Any process that modulates the frequency, rate or extent of gap junction assembly. GO:0014852 regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014852 Any process that modulates the frequency, rate or extent of skeletal muscle contraction by variation of the pattern of stimulation by nervous system. GO:0014850 response to muscle activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014850 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus. GO:0014856 skeletal muscle cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014856 The multiplication or reproduction of skeletal muscle cells, resulting in the expansion of a cell population. GO:0014855 striated muscle cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014855 The multiplication or reproduction of striated muscle cells, resulting in the expansion of a cell population. Striated muscles contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. GO:0014854 response to inactivity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014854 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inactivity stimulus. GO:0014853 regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014853 regulation of excitatory post-synaptic membrane potential involved in skeletal muscle contraction Any process, involved in skeletal muscle contraction, that modulates the establishment or extent of the excitatory postsynaptic potential (EPSP). Excitatory postsynaptic potential (EPSP) is a temporay increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential. GO:0000219 obsolete vacuolar hydrogen-transporting ATPase biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000219 V-ATPase|vacuolar hydrogen-transporting ATPase OBSOLETE. (Was not defined before being made obsolete). GO:0000218 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000218 CHEBI:38373 3-dodecenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38373 GO:0000217 DNA secondary structure binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000217 Interacting selectively and non-covalently with DNA containing secondary structure elements such as four-way junctions, bubbles, loops, Y-form DNA, or double-strand/single-strand junctions. GO:0000216 obsolete M/G1 transition of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000216 M/G1 transition of mitotic cell cycle OBSOLETE. Progression from M phase to G1 phase of the mitotic cell cycle. CHEBI:38371 2-dodecenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38371 GO:0097127 cyclin B3-CDK2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097127 A protein complex consisting of cyclin B3 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. GO:0097126 cyclin B2-CDK1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097126 A protein complex consisting of cyclin B2 and cyclin-dependent kinase 1 (CDK1). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. GO:0097129 cyclin D2-CDK4 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097129 A protein complex consisting of cyclin D2 and cyclin-dependent kinase 4 (CDK4). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. GO:0097128 cyclin D1-CDK4 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097128 A protein complex consisting of cyclin D1 and cyclin-dependent kinase 4 (CDK4). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. UBERON:0001926 lateral geniculate body biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001926 corpus geniculatum laterales|external geniculate body|corpus geniculatus lateralis|corpus geniculatum laterale|lateral geniculate nucleus|nucleus corporis geniculati lateralis|lateral geniculate complex|LGN|nucleus geniculatus lateralis|LGB|corpus geniculatum externum the group of neurons that serve as the primary processor of visual information received from the retina via the optic tract and send processed information to the visual cortex of the occipital lobe GO:0014827 intestine smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014827 A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the intestine. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The intestine is the section of the alimentary canal from the stomach to the anal canal. It includes the large intestine and small intestine. GO:0014826 vein smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014826 A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the vein. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The vein is a vessel carrying blood away from the capillary beds. GO:0014825 stomach fundus smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014825 A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the fundus of stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The fundus is the portion of the stomach that lies above the cardiac notch. GO:0014824 artery smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014824 A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the artery. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The artery is a vessel carrying blood away from the heart. GO:0014829 vascular associated smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014829 vascular smooth muscle contraction A process, occurring in the vascular tissue, whereby actin/myosin complex activity generates force through ATP hydrolysis resulting in a change in smooth muscle geometry. This process is always coupled to chemo-mechanical energy conversion. GO:0014828 distal stomach smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014828 A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the distal stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The distal stomach is composed of the lower body and antrum and develops strong peristaltic phasic contractions that increase in amplitude as they propagate toward the pylorus. GO:0014823 response to activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014823 response to exercise Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an activity stimulus. GO:0014822 detection of wounding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014822 detection of injury The series of events by which an injury stimulus is received and converted into a molecular signal. GO:0014821 phasic smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014821 A process in which force is generated within phasic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the phasic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Phasic smooth muscle contraction occurs in a series of discrete contractions and relaxations. GO:0014820 tonic smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014820 A process in which force is generated within tonic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the tonic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Tonic smooth muscle contraction occurs as a sustained continuous contraction. CHEBI:38340 hydroxypyrimidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38340 CHEBI:38342 L-sorbose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38342 GO:0097101 blood vessel endothelial cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097101 The process involved in the specification of identity of a blood vessel endothelial cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. A blood vessel endothelial cell is an endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels. UBERON:0001913 milk biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001913 mammary gland milk An emulsion of fat globules within a fluid that is secreted by the mammary gland during lactation. GO:0097100 supercoiled DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097100 Interacting selectively and non-covalently with supercoiled DNA. For example, during replication and transcription, template DNA is negatively supercoiled in the receding downstream DNA and positively supercoiled in the approaching downstream DNA. GO:0097103 endothelial stalk cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097103 angiogenic stalk cell fate specification The process involved in the specification of identity of an endothelial stalk cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. An endothelial stalk cell is a specialized endothelial cell which follows behind the tip cell of an angiogenic sprout. UBERON:0001916 endothelium of arteriole biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001916 arteriole endothelium An endothelium that is part of an arteriole [Automatically generated definition]. GO:0097102 endothelial tip cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097102 angiogenic tip cell fate specification The process involved in the specification of identity of an endothelial tip cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. An endothelial tip cell is a specialized endothelial cell localized to the leading edge of an angiogenic sprout that senses extracellular signals and guides the directed growth of blood vessels. UBERON:0001915 endothelium of capillary biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001915 capillary endothelium|endothelium of capillary vessel|blood capillary endothelium|capillary vessel endothelium|endothelium of blood capillary An endothelium that is part of a capillary [Automatically generated definition]. UBERON:0001912 lobule of mammary gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001912 mammary gland lobule|lactiferous acinus|lactiferous gland lobule|acinus of mammary gland|lobule of lactiferous gland|lactiferous lobule|mammary acinus|lobule of mammary gland Organ component of the mammary gland which consists of an aggregate of mammary alveoli that communicate with a lobular lactiferous duct.[FMA] UBERON:0001911 mammary gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001911 milk patch|mamma|glandula mammaria|lobe of breast|glandula mammaria|mammae|lobe of mammary gland|Brustdruese|dug|lactiferous gland A specialized accessory gland of the skin of mammals that secretes milk. The gland is typically only developed in females, and regresses in males. GO:0014838 myoblast fate specification involved in skeletal muscle regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014838 The process in which a satellite cell becomes capable of differentiating autonomously into a myoblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. GO:0014837 myoblast fate determination involved in skeletal muscle regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014837 The process in which a satellite cell becomes capable of differentiating autonomously into a myoblast regardless of its environment; upon determination, the cell fate cannot be reversed. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. GO:0014836 myoblast fate commitment involved in skeletal muscle regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014836 The process in which the developmental fate of a satellite cell becomes restricted such that it will develop into a myoblast. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. GO:0014835 myoblast differentiation involved in skeletal muscle regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014835 The process in which a relatively unspecialized satellite cell acquires specialized features of a myoblast. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. UBERON:0001918 endothelium of venule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001918 venule endothelium An endothelium that is part of a venule [Automatically generated definition]. UBERON:0001917 endothelium of artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001917 artery endothelium|arterial endothelium An endothelium that is part of an artery [Automatically generated definition]. UBERON:0001919 endothelium of vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001919 vein endothelium|veinous endothelium|venous endothelium An endothelium that is part of a vein [Automatically generated definition]. GO:0014839 myoblast migration involved in skeletal muscle regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014839 mononucleate cell migration involved in skeletal muscle regeneration The process in which a myoblast migrates along an entire fiber to the site of injury. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. GO:0014830 arteriole smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014830 A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the arteriole. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The arteriole is the smallest division of the artery located between the muscular arteries and the capillaries. CHEBI:38358 (2E,4E)-hexa-2,4-dienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38358 GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014834 satellite cell self-renewal|satellite cell compartment self-renewal involved in skeletal muscle regeneration|satellite cell population maintenance Any process by which the number of skeletal muscle satellite cells in a skeletal muscle is maintained during muscle regeneration. There are at least three mechanisms by which this is achieved. Skeletal muscle satellite stem cell asymmetric division ensures satellite stem cell numbers are kept constant. Symmetric division of these cells amplifies the number of skeletal muscle satellite stem cells. Some adult skeletal muscle myoblasts (descendants of activated satellite cells) can develop back into quiescent satellite cells, replenishing the overall pool of satellite cells. GO:0014833 skeletal muscle satellite stem cell asymmetric division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014833 satellite cell asymmetric division The asymmetric division of a skeletal muscle satellite stem cell to produce two daughter cells, one of which is destined to differentiate and the other to be a quiescent cell that restocks the satellite cell pool. GO:0014832 urinary bladder smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014832 A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary bladder. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary bladder is a musculomembranous sac along the urinary tract. GO:0014831 gastro-intestinal system smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014831 A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the gastro-intestinal system. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The gastro-intestinal system generally refers to the digestive structures stretching from the mouth to anus, but does not include the accessory glandular organs (liver, pancreas and biliary tract). GO:0097109 neuroligin family protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097109 Interacting selectively and non-covalently with a member of the neuroligin protein family, neuronal cell surface proteins that mediate synapse formation. GO:0097108 hedgehog family protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097108 Interacting selectively and non-covalently with a member of the hedgehog protein family, signaling proteins involved in development. GO:0097105 presynaptic membrane assembly biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0097105 pre-synaptic membrane assembly The aggregation, arrangement and bonding together of a set of components to form a presynaptic membrane, including any proteins associated with the membrane, but excluding other cellular components. A presynaptic membrane is a specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction. CHEBI:38356 trans-hex-4-enoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38356 GO:0097104 postsynaptic membrane assembly biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0097104 post-synaptic membrane assembly The aggregation, arrangement and bonding together of a set of components to form a postsynaptic membrane, a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). CHEBI:38355 hex-4-enoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38355 GO:0097107 postsynaptic density assembly biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0097107 post synaptic density assembly|PSD assembly|post-synaptic density assembly The aggregation, arrangement and bonding together of a set of components to form a postsynaptic density, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse. GO:0097106 postsynaptic density organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097106 PSD organization|post-synaptic density organization|postsynaptic density organisation|post synaptic density organization A process that results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic density, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse. GO:0097156 fasciculation of motor neuron axon biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097156 The collection of motor neuron axons into a bundle of rods, known as a fascicle. GO:0097155 fasciculation of sensory neuron axon biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097155 The collection of sensory neuron axons into a bundle of rods, known as a fascicle. GO:0097158 pre-mRNA intronic pyrimidine-rich binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097158 pre-messenger RNA intronic pyrimidine-rich binding Interacting selectively and non-covalently with a pyrimidine-rich (CU-rich) intronic sequence of a pre-messenger RNA (pre-mRNA). GO:0097157 pre-mRNA intronic binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097157 pre-messenger RNA intronic binding Interacting selectively and non-covalently with an intronic sequence of a pre-messenger RNA (pre-mRNA). UBERON:0001987 placenta biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001987 allantoic placenta|eutherian placenta organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin[GO]. The fetal portion of the placenta is known as the villous chorion. The maternal portion is known as the decidua basalis. The two portions are held together by anchoring villi that are anchored to the decidua basalis by the cytotrophoblastic shell. GO:0097152 mesenchymal cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097152 mesenchymal cell apoptosis Any apoptotic process in a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types. UBERON:0001986 endothelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001986 A layer of epithelium that lines the heart, blood vessels (endothelium, vascular), lymph vessels (endothelium, lymphatic), and the serous cavities of the body[MESH]. Simple squamous epithelium which lines blood and lymphatic vessels and the heart[FMA] GO:0097151 positive regulation of inhibitory postsynaptic potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097151 positive regulation of inhibitory post-synaptic membrane potential|positive regulation of IPSP Any process that activates or increases the frequency, rate or extent of inhibitory postsynaptic potential (IPSP). IPSP is a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential. GO:0097154 GABAergic neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097154 The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic neuron. UBERON:0001988 feces biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001988 matières fécales@fr|fecal matter|portion of excrement|spoor|merde@fr|dung|partie de la merde@fr|droppings|teil der fäkalien@de|stool|portion of guano|fewmet|spraint|scat|portion of fecal material|faeces|portionem cacas|excreta|cow dung|ordure|portion of feces|portion of fecal matter|portion of dung|excrement|frass|guano|portion of scat|fecal material|portion of faeces|piece of shit|porción de mierda@es|cow pat Portion of semisolid bodily waste discharged through the anus[MW,modified] GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097153 Reactome:R-HSA-6800797 caspase activity|metacaspase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic process. GO:0014805 smooth muscle adaptation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014805 smooth muscle plasticity Any process in which smooth muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities. GO:0014804 terminal cisterna lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0014804 The region between the inner and outer lipid bilayers of the terminal cisterna envelope. This space is enriched in calsequestrin. GO:0014803 longitudinal sarcoplasmic reticulum lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0014803 The region between the inner and outer lipid bilayers of the longitudinal sarcoplasmic reticulum envelope. The longitudinal sarcoplasmic reticulum lumen is continuous with the lumen contained within the terminal cisternae. GO:0097150 neuronal stem cell population maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097150 Any process in by an organism or tissue maintains a population of neuronal stem cells. GO:0014802 terminal cisterna biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0014802 Wikipedia:Terminal_cisterna The portion of sarcoplasmic reticulum devoted to calcium ion storage and calcium ion release. GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014809 Any process that modulates the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction. GO:0014808 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014808 release of sequestered calcium ion by sarcoplasmic reticulum into cytosol The process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels. GO:0014807 regulation of somitogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014807 Any process that modulates the frequency, rate or extent of somitogenesis. GO:0014806 smooth muscle hyperplasia biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014806 A process, occurring in smooth muscle, in which there is an increase in cell number by cell division, often leading to an increase in the size of an organ. CHEBI:38326 thiazine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38326 CHEBI:38325 muscarinic agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38325 CHEBI:38324 cholinergic agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38324 GO:0014801 longitudinal sarcoplasmic reticulum biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0014801 The portion of the free sarcoplasmic reticulum consisting of longitudinal tubules that connect terminal cisternae. CHEBI:38329 oxazolidines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38329 UBERON:0001994 hyaline cartilage tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001994 chondroid cartilage|hyaline cartilage Cartilage tissue primarily composed of type II collagen (thin fibrils) and a glassy appearance. UBERON:0001996 elastic cartilage tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001996 yellow elastic cartilage tissue|reticular cartilage|elastic cartilage tissue|elastic cartilage|yellow cartilage|yellow elastic cartilage Cartilage tissue that is flexible and contains abundant elastic fibers. UBERON:0001995 fibrocartilage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001995 fibrocartilage tissue|stratified cartilage tissue Cartilage tissue intermediate between hyaline cartilage and dense connective tissue; contains of abundant collagen fibers; chondrocytes often arranged in columns. CHEBI:38323 cholinergic drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38323 GO:0097159 organic cyclic compound binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097159 Interacting selectively and non-covalently with an organic cyclic compound, any molecular entity that contains carbon arranged in a cyclic molecular structure. CHEBI:38320 (+)-usnic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38320 GO:0097167 circadian regulation of translation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097167 regulation of mRNA translation in response to circadian clock Any process that modulates the frequency, rate or extent of mRNA translation with a regularity of approximately 24 hours. UBERON:0001979 venule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001979 venula One of the minute vessels that collect deoxygenated blood from the capillary plexuses returns it to the veins GO:0097166 lens epithelial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097166 The multiplication or reproduction of lens epithelial cells, resulting in the expansion of a cell population. Lens epithelial cells make up the lens epithelium, which is located in the anterior portion of the lens between the lens capsule and the lens fibers and is a simple cuboidal epithelium. The epithelial cells of the lens regulate most of the homeostatic functions of the lens such as osmolarity and liquid volume. The lens epithelial cells also serve as the progenitors for new lens fibers. The lens epithelium constantly lays down fibers in the embryo, fetus, infant, and adult, and continues to lay down fibers for lifelong growth. GO:0097169 AIM2 inflammasome complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097169 A protein complex that consists of AIM2, ASC, and caspase-1. AIM2 is a member of the HN-200 protein family that appears to be the sensor of cytosolic double-stranded DNA. GO:0097168 mesenchymal stem cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097168 MSC proliferation The multiplication or reproduction of mesenchymal stem cells, resulting in the expansion of a stem cell population. A mesenchymal stem cell, or MSC, is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells. GO:0097163 sulfur carrier activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097163 Covalently binding to sulfur and delivering it to an acceptor molecule. UBERON:0001976 epithelium of esophagus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001976 epithelial tissue of oesophagus|epithelium of oesophagus|oesophagus epithelial tissue|esophageal epithelium|oesophagus epithelium|epithelial tissue of gullet|epithelium of gullet|gullet epithelium|esophagus epithelium|epithelial tissue of esophagus|gullet epithelial tissue|esophagus epithelial tissue the epithelial layer that lines the luminal space of the esophagus UBERON:0001975 serosa of esophagus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001975 gullet serous membrane|esophagus serous membrane|serosa of gullet|esophagus serosa|gullet serosa|serous membrane of oesophagus|tunica serosa oesophageae|oesophagus serous membrane|serosa of oesophagus|serous membrane of esophagus|serosa of abdominal part of esophagus|serous membrane of gullet|oesophagus serosa|serous coat of oesophagus A serous membrane that is part of a esophagus [Automatically generated definition]. GO:0097162 MADS box domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097162 Interacting selectively and non-covalently with a MADS box domain, a protein domain that encodes the DNA-binding MADS domain. The MADS domain binds to DNA sequences of high similarity to the motif CC[A/T]6GG termed the CArG-box. MADS-domain proteins are generally transcription factors. The length of the MADS-box is in the range of 168 to 180 base pairs. GO:0097165 nuclear stress granule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097165 A dense aggregation in the nucleus composed of proteins and RNAs that appear when the cell is under stress. UBERON:0001978 parenchyma of pancreas biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001978 pancreatic parenchyma|pancreas parenchyma GO:0097164 ammonium ion metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097164 ammonium ion metabolism|ammonium metabolic process The chemical reactions and pathways involving the ammonium ion. GO:0014816 skeletal muscle satellite cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014816 The process in which a relatively unspecialized cell acquires specialized features of a satellite cell. GO:0014815 initiation of skeletal muscle satellite cell activation by growth factor signaling, involved in skeletal muscle regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014815 Signalling between growth factors and their receptors that results in the activation of satellite cell, where this process is involved in skeletal muscle regeneration. Satellite cells are quiescent cells that are located between the basal lamina and the plasmalemma of the muscle fiber, which are the main contributors to postnatal muscle growth. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage. GO:0097161 DH domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097161 Interacting selectively and non-covalently with a DH (Dbl homology) domain of a protein. The DH domain contains three structurally conserved regions separated by more variable regions. It is composed of 11 alpha helices that are folded into a flattened, elongated alpha-helix bundle in which two of the three conserved regions, conserved region 1 (CR1) and conserved region 3 (CR3), are exposed near the centre of one surface. CR1 and CR3, together with a part of alpha-6 and the DH/PH (pleckstrin homology) junction site, constitute the Rho GTPase interacting pocket. GO:0014814 axon regeneration at neuromuscular junction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014814 The regrowth of axons following their loss or damage at the neuromuscular junction. Motor axons regenerate after injury and they form neuro-muscular junctions with skeletal myofibers similar to normal ones. GO:0097160 polychlorinated biphenyl binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097160 PCB binding|polychlorobiphenyl binding Interacting selectively and non-covalently with a polychlorinated biphenyl (PCB), a biphenyl compound containing between 2 and 10 chlorine atoms attached to the two benzene rings. GO:0014813 skeletal muscle satellite cell commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014813 The process in which the developmental fate of a cell becomes restricted such that it will develop into a satellite cell. GO:0014819 regulation of skeletal muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014819 Any process that modulates the frequency, rate or extent of skeletal muscle contraction. GO:0014818 skeletal muscle satellite cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014818 The process in which a cell becomes capable of differentiating autonomously into a skeletal muscle satellite cell regardless of its environment; upon determination, the cell fate cannot be reversed. UBERON:0011300 gray matter of telencephalon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011300 predominantly gray regional part of telencephalon A portion of gray matter that is part of a telencephalon. GO:0014817 skeletal muscle satellite cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014817 The process in which a cell becomes capable of differentiating autonomously into a skeletal muscle satellite cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. CHEBI:38338 aminopyrimidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38338 CHEBI:38337 pyrimidone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38337 CHEBI:38336 dithiolanecarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38336 CHEBI:38335 dithiolane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38335 GO:0014812 muscle cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014812 The orderly movement of a muscle cell from one site to another, often during the development of a multicellular organism. GO:0014811 negative regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014811 Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction. GO:0014810 positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014810 Any process that activates, maintains or increases the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction. CHEBI:38339 formamidopyrimidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38339 UBERON:0001982 capillary biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001982 blood capillary|capillary vessel Any of the smallest blood vessels connecting arterioles with venules. UBERON:0001985 corneal endothelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001985 endothelium of cornea|epithelium posterius corneae|cornea endothelium A monolayer of specialized, flattened, mitochondria-rich cells that lines the posterior surface of the cornea and faces the anterior chamber of the eye[WP]. CHEBI:38333 thiazolidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38333 UBERON:0001981 blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001981 region of vascular tree organ|vascular tree organ region|vas sanguineum|vascular element A vessel through which blood circulates in the body. CHEBI:38332 pyrancarbaldehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38332 UBERON:0001980 arteriole biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001980 arteriola The smallest division of the artery located between the muscular arteries and the capillaries[GO]. CHEBI:38331 11-tetradecenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38331 UBERON:0001969 blood plasma biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001969 plasma|portion of plasma|blood plasm|portion of blood plasma The liquid component of blood, in which erythrocytes are suspended. GO:0097134 cyclin E1-CDK2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097134 A protein complex consisting of cyclin E1 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. GO:0097133 cyclin D3-CDK6 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097133 A protein complex consisting of cyclin D3 and cyclin-dependent kinase 6 (CDK6). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. UBERON:0001968 semen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001968 ejaculate|sperm Organism substance that is composed of sperm cells suspended in seminal fluid. CHEBI:28989 2,4,5-trichlorocyclohexa-2,5-dien-1-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28989 GO:0097136 Bcl-2 family protein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097136 A protein complex that consists of members of the Bcl-2 family of anti- and proapoptotic regulators. Bcl-2 proteins respond to cues from various forms of intracellular stress, such as DNA damage or cytokine deprivation, and interact with opposing family members to determine whether or not the caspase proteolytic cascade should be unleashed. GO:0097135 cyclin E2-CDK2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097135 A protein complex consisting of cyclin E2 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. GO:0097130 cyclin D3-CDK4 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097130 A protein complex consisting of cyclin D3 and cyclin-dependent kinase 4 (CDK4). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. CHEBI:28985 (R)-1,2-epoxypropane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28985 GO:0097132 cyclin D2-CDK6 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097132 A protein complex consisting of cyclin D2 and cyclin-dependent kinase 6 (CDK6). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. GO:0097131 cyclin D1-CDK6 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097131 A protein complex consisting of cyclin D1 and cyclin-dependent kinase 6 (CDK6). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner. CHEBI:28987 abietic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28987 CHEBI:28982 (S)-1,2-epoxypropane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28982 CHEBI:28984 aluminium atom biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28984 CHEBI:38305 gibberellin monocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38305 CHEBI:38304 diazolidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38304 CHEBI:38303 azirinopyrroloindole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38303 CHEBI:38308 N-acylimidazole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38308 CHEBI:38307 imidazolyl carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38307 CHEBI:38306 imidazole-4-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38306 UBERON:0001972 submucosa of esophagus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001972 tela submucosa esophagi|tela submucosa oesophageae|esophagus submucosa|gullet submucosa|tela submucosa oesophagi|submucosa of oesophagus|esophageal submucosa|submucosa of esophagus|oesophagus submucosa|submucous layer of esophagus|tela submucosa of esophagus|tela submucosa (oesophagus)|submucosa of gullet A submucosa that is part of a esophagus [Automatically generated definition]. UBERON:0001971 gastric juice biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001971 stomach secretion|succus gastricus . UBERON:0001974 lamina propria of esophagus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001974 lamina propria of oesophagus|oesophagus lamina propria mucosae|lamina propria mucosa of gullet|lamina propria mucosa of esophagus|oesophagus lamina propria|esophageal lamina propria|gullet lamina propria mucosa|lamina propria mucosae of gullet|esophagus lamina propria mucosa|esophagus lamina propria mucosae|gullet lamina propria mucosae|lamina propria of gullet|lamina propria mucosa of oesophagus|gullet lamina propria|esophagus lamina propria|lamina propria mucosae of esophagus|lamina propria mucosae of oesophagus|oesophagus lamina propria mucosa A lamina propria that is part of a esophagus [Automatically generated definition]. GO:0097138 BAD-BCL-2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097138 A heterodimeric protein complex consisting of BAD and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators. GO:0097137 BAD-BCL-xl complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097137 A heterodimeric protein complex consisting of BAD and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators. UBERON:0001970 bile biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001970 gall|fel vital aqueous secretion of the liver that is formed by hepatocytes and modified down stream by absorptive and secretory properties of the bile duct epithelium. GO:0097139 BID-BCL-2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097139 A heterodimeric protein complex consisting of BID and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators. UBERON:0001958 terminal bronchiole epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001958 epithelium of bronchiolus terminalis|epithelium of terminal bronchiole|epithelial tissue of terminal bronchiole|terminal bronchiole epithelial tissue|bronchiolus terminalis epithelial tissue|bronchiolus terminalis epithelium|terminal bronchiole epithelium|epithelial tissue of bronchiolus terminalis An epithelium that lines a terminal bronchiole. GO:0097145 BAK complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097145 An oligomeric protein complex consisting of BAK, a member of the Bcl-2 family of anti- and proapoptotic regulators. UBERON:0001957 submucosa of bronchus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001957 submucous layer of bronchi|bronchial submucosa|tela submucosa bronchi|bronchi submucosa|bronchial trunk submucosa|bronchus submucosa|submucosa of bronchi|submucosa of bronchial trunk A submucosa that is part of a bronchus [Automatically generated definition]. GO:0097144 BAX complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097144 An oligomeric protein complex consisting of BAX, a member of the Bcl-2 family of anti- and proapoptotic regulators. GO:0097147 NOXA-BCL-2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097147 A heterodimeric protein complex consisting of NOXA and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators. GO:0097146 NOXA-BCL-xl complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097146 A heterodimeric protein complex consisting of NOXA and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators. UBERON:0001959 white pulp of spleen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001959 spleen white pulp|white pulp|pulpa alba|splenic white pulp|noduli lymphoidei splenici the parenchymatous tissue of the spleen that surrounds splenic blood vessels, consists of compact masses of lymphatic cells and is where foreign material removed from the blood is used to initiate an immune reaction that results in the production of antibodies UBERON:0001954 Ammon's horn biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001954 hippocampus major|ammon horn|hippocampus proper|ammon gyrus|Ammon's horn|cornu ammonis|Ammon horn fields|Ammons horn|hippocampus proprius|hippocampus A part of the brain consisting of a three layered cortex located in the forebrain bordering the medial surface of the lateral ventricle. The term hippocampus is often used synonymously with hippocampal formation which consists of the hippocampus proper or Cornu Ammonis, the dentate gyrus and the subiculum. GO:0097141 BIM-BCL-2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097141 A heterodimeric protein complex consisting of BIM and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators. CHEBI:28997 2'-deoxyinosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28997 GO:0097140 BIM-BCL-xl complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097140 A heterodimeric protein complex consisting of BIM and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators. CHEBI:28999 N-acetyl-9-O-acetylneuraminate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28999 GO:0097143 PUMA-BCL-xl complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097143 A heterodimeric protein complex consisting of PUMA and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators. UBERON:0001956 cartilage of bronchus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001956 bronchial cartilage|bronchial cartilage ring|bronchi cartilage|bronchial trunk cartilage|cartilage of bronchi|cartilage of bronchial trunk|bronchus cartilage|cartilagines bronchiales The hyaline cartilaginous structures that support the bronchi, present as irregular rings in the larger bronchi (and not as regular as in the trachea), and as small plates and islands in the smaller bronchi; as the branching continues through the bronchial tree, the amount of hyaline cartilage in the walls decreases until it is absent in the smallest bronchioles[MP]. GO:0097142 PUMA-BCL-2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097142 A heterodimeric protein complex consisting of PUMA and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators. CHEBI:28992 2-hydroxychromene-2-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28992 CHEBI:28995 2,4-dichlorobenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28995 CHEBI:28991 (2S,3R)-aldono-1,5-lactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28991 CHEBI:28990 2-hydroxy-6-(2-hydroxyphenoxy)-6-oxo-cis,cis-hexa-2,4-dienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28990 CHEBI:38316 pyrimidinecarboxylate anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38316 CHEBI:38315 beta-D-arabinoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38315 CHEBI:38314 pyrazines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38314 CHEBI:38313 diazines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38313 CHEBI:38319 usnic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38319 CHEBI:38317 EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38317 UBERON:0001961 mucosa-associated lymphoid tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001961 epithelio-lymphoid tissue|mucosa-associated lymphoid tissue|MALT|mucosal-associated lymphoid tissue|mucosa associated lymphatic tissue|mucosa associated lymphoid tissue|mucosal-associated lymphatic tissue diffuse system of small concentrations of lymphoid tissue found in various sites of the body such as the gastrointestinal tract, thyroid, breast, lung, salivary glands, eye, and skin[WP]. Mucosal-associated lymphoid tissue is typically found as nodules associated with mucosal epithelia with distinct internal structures including B- and T-zones for the activation of lymphocytes[GO]. UBERON:0001960 periarterial lymphatic sheath biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001960 periarteriolar sheath|splenic periarteriolar lymphoid sheath|spleen periarteriolar lymphatic sheath|periarterial lymphoid sheath|T cell domain of the splenic white pulp|PALS The area of the spleen in which T cells surround the central arteriole UBERON:0001963 bronchial-associated lymphoid tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001963 bronchus associated lymphoid tissue|BALT A diffuse collection of lymphpoid cells that participate in airway immune responses UBERON:0001962 gut-associated lymphoid tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001962 gut associated lymphoid tissue|GALT Mucosa-associated lymphoid tissue in digestive tract. includes Peyer's patches, appendix, and solitary lymph nodules[GO]. GO:0097149 centralspindlin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097149 A heterotetrameric protein complex playing a key role in the formation of the central spindle in mitosis. Made up of two molecules each of a mitotic kinesin (ZEN-4 in Caenorhabditis elegans or MKLP1 in mammals) and of two molecules each of a GTPase activating protein (GAP) factor (CYK-4 in Caenorhabditis elegans or MgcRacGAP in mammals). GO:0097148 BCL-2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097148 A homodimeric protein complex consisting of BCL-2, a member of the Bcl-2 family of anti- and proapoptotic regulators. CHEBI:38311 cephem biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38311 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048101 calcium- and calmodulin-regulated cGMP-specific phosphodiesterase activity|calcium- and calmodulin-regulated cGMP phosphodiesterase activity|calcium- and calmodulin-regulated cyclic-GMP phosphodiesterase activity|calcium/calmodulin-regulated cGMP-specific phosphodiesterase activity Catalysis of the reaction: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate. The reaction is calmodulin and calcium-sensitive. GO:0000167 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000167 GO:0048100 wing disc anterior/posterior pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048100 The establishment, maintenance and elaboration of the anterior/posterior axis of the wing disc, a precursor to the wing. GO:0000166 nucleotide binding biolink:MolecularActivity go-plus goslim_pir|goslim_plant|goslim_metagenomics|goslim_chembl http://purl.obolibrary.org/obo/GO_0000166 Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose. GO:0000165 MAPK cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000165 Wikipedia:MAPK_cascade|Wikipedia:Mitogen-activated_protein_kinase MAPK signalling|mitogen-activated protein kinase cascade|MAPK signaling|MAPKKK cascade|MAPKKK cascade during sporulation|MAP kinase cascade|MAP kinase kinase kinase cascade|MAPK signal transduction|ERK/MAPK cascade An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tiers: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell. GO:0000164 protein phosphatase type 1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000164 A protein complex that possesses magnesium-dependent protein serine/threonine phosphatase (AMD phosphatase) activity, and consists of a catalytic subunit and one or more regulatory subunits that dictates the phosphatase's substrate specificity, function, and activity. GO:1903509 liposaccharide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903509 liposaccharide metabolism The chemical reactions and pathways involving liposaccharide. GO:1903508 positive regulation of nucleic acid-templated transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903508 activation of nucleic acid-templated transcription|up-regulation of nucleic acid-templated transcription|up regulation of nucleic acid-templated transcription|upregulation of nucleic acid-templated transcription Any process that activates or increases the frequency, rate or extent of nucleic acid-templated transcription. CHEBI:87260 O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87260 GO:1903507 negative regulation of nucleic acid-templated transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903507 down-regulation of nucleic acid-templated transcription|downregulation of nucleic acid-templated transcription|down regulation of nucleic acid-templated transcription|inhibition of nucleic acid-templated transcription Any process that stops, prevents or reduces the frequency, rate or extent of nucleic acid-templated transcription. GO:1903506 regulation of nucleic acid-templated transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903506 Any process that modulates the frequency, rate or extent of nucleic acid-templated transcription. GO:0000169 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000169 GO:1903505 regulation of establishment of actomyosin contractile ring localization involved in mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903505 Any process that modulates the frequency, rate or extent of establishment of actomyosin contractile ring localization involved in mitotic cell cycle. GO:0000168 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000168 GO:0048109 peptide cross-linking via 2-amino-3-isothiazolidinone-L-serine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048109 RESID:AA0344 The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl serine cross-link through a process of forming first an intermediate cysteine sulfenic acid by peroxide oxidation, followed by condensation with the alpha-amido of the following serine residue and the release of water. GO:1903504 regulation of mitotic spindle checkpoint biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_1903504 regulation of mitotic cell cycle spindle checkpoint Any process that modulates the frequency, rate or extent of mitotic spindle checkpoint. CL:0011027 skeletal muscle fibroblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0011027 skeleton muscle fibroblast Any fibroblast that is part of skeletal muscle tissue. GO:0048108 peptide cross-linking via 4-amino-3-isothiazolidinone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048108 The formation of 4-amino-3-isothiazolinone cross-links by the formation of a sulfenylamide bond between cysteine or cysteine sulfenic acid, and the alpha-amido of the following residue. GO:1903503 ATPase inhibitor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1903503 A protein complex which is capable of ATPase inhibitor activity. CL:0011026 progenitor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0011026 A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses. GO:1903502 translation repressor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1903502 A protein complex which is capable of translation repressor activity. GO:0048107 4-amino-3-isothiazolidinone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048107 4-amino-3-isothiazolidinone synthesis|4-amino-3-isothiazolidinone formation|4-amino-3-isothiazolidinone biosynthesis|4-amino-3-isothiazolidinone anabolism The chemical reactions and pathways resulting in the formation of 4-amino-3-isothiazolinone, five-membered saturated heterocyclic ring structures containing a sulfur and a nitrogen in the 1-position and 2-positions respectively. GO:1903501 positive regulation of mitotic actomyosin contractile ring assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903501 upregulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|upregulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis|up regulation of contractile ring assembly involved in mitotic cytokinesis|activation of contractile ring assembly involved in mitotic cytokinesis|up regulation of mitotic actomyosin contractile ring assembly|positive regulation of contractile ring assembly involved in mitotic cytokinesis|up regulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|activation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|positive regulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|activation of actomyosin contractile ring assembly involved in cytokinesis after mitosis|up-regulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis|positive regulation of mitotic cytokinesis, actomyosin contractile ring assembly|upregulation of mitotic actomyosin contractile ring assembly|up-regulation of contractile ring assembly involved in mitotic cytokinesis|up-regulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|positive regulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis|up regulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis|activation of mitotic actomyosin contractile ring assembly|up-regulation of mitotic actomyosin contractile ring assembly|upregulation of contractile ring assembly involved in mitotic cytokinesis Any process that activates or increases the frequency, rate or extent of mitotic actomyosin contractile ring assembly. GO:0048106 establishment of thoracic bristle planar orientation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048106 establishment of body bristle planar orientation Orientation along the body surface of bristles, sensory organs originating from a sensory organ precursor cell, such that they all point in a uniform direction. CL:0011024 double negative T regulatory cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0011024 double-negative alpha-beta regulatory T cell|CD4-negative, CD8-negative, alpha-beta regulatory T cells|DN Treg A double negative thymocyte that is CD3-positive, CD4-negative, CD8-negative, that that are present in the periphery in very low numbers and predominantly produce INF-gamma, TNF-alpha, and a low amount of TGF-beta, but not IL-2, IL-4, IL-10 or IL-13 upon activation. GO:1903500 negative regulation of mitotic actomyosin contractile ring assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903500 down regulation of contractile ring assembly involved in mitotic cytokinesis|down regulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis|down-regulation of mitotic actomyosin contractile ring assembly|inhibition of actomyosin contractile ring assembly involved in cytokinesis after mitosis|down regulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|downregulation of contractile ring assembly involved in mitotic cytokinesis|downregulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|downregulation of mitotic actomyosin contractile ring assembly|down-regulation of contractile ring assembly involved in mitotic cytokinesis|negative regulation of contractile ring assembly involved in mitotic cytokinesis|down regulation of mitotic actomyosin contractile ring assembly|down-regulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|negative regulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|inhibition of mitotic actomyosin contractile ring assembly|negative regulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis|inhibition of contractile ring assembly involved in mitotic cytokinesis|down-regulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis|negative regulation of mitotic cytokinesis, actomyosin contractile ring assembly|inhibition of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|downregulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis Any process that stops, prevents or reduces the frequency, rate or extent of mitotic actomyosin contractile ring assembly. GO:0048105 establishment of body hair planar orientation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048105 Orientation of body hairs, projections from the surface of an organism, such that the hairs all point in a uniform direction along the surface. GO:0000163 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000163 GO:0000162 tryptophan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000162 MetaCyc:TRPSYN-PWY tryptophan anabolism|tryptophan synthesis|tryptophan formation|aromatic amino acid family biosynthetic process, anthranilate pathway|tryptophan biosynthesis The chemical reactions and pathways resulting in the formation of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid; tryptophan is synthesized from chorismate via anthranilate. GO:0048104 establishment of body hair or bristle planar orientation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048104 Orientation of hairs or sensory bristles that cover the body surface of an adult, such that they all point in a uniform direction along the plane of the epithelium from which they project. GO:0000161 osmosensory signaling MAPK cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000161 osmolarity sensing, activation of MAP kinase kinase activity|osmolarity sensing, activation of MAPKK activity|MAPKKK cascade involved in osmosensory signalling pathway|activation of MAPKKK activity during osmolarity sensing|Hog1/Sty1 stress-activated MAPK cascade|MAPKKK cascade during osmolarity sensing|activation of MAPK activity involved in osmosensory signaling pathway|activation of MAPKKK activity involved in osmosensory signaling pathway|MAPK cascade involved in osmosensory signaling pathway|inactivation of MAPK activity involved in osmosensory signaling pathway|termination of MAPK activity during osmolarity sensing|osmolarity sensing, MAPKKK cascade|activation of MAPKK activity during osmolarity sensing|osmolarity sensing, activation of MAP kinase kinase kinase activity|activation of Pbs2 kinase|Hog1 MAPK pathway|MAPKKK cascade involved in osmosensory signaling pathway|activation of MAPKK activity involved in osmosensory signaling pathway|High Osmolarity Glycerol (HOG) MAPK pathway|osmolarity sensing, activation of MAPKKK activity|osmolarity sensing, activation of MAPK activity A series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays one or more of the signals, containing at least a Hog1/Sty1 family MAPK, a Pbs2/Wis1 family MAPKK and a Ssk2/Win1 family MAP3K. GO:0048103 somatic stem cell division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048103 somatic stem cell renewal The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line. CHEBI:63299 carbohydrate derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63299 GO:0048102 autophagic cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048102 autophagic death|type II programmed cell death|programmed cell death by macroautophagy|autosis|programmed cell death by autophagy A form of programmed cell death that is accompanied by the formation of autophagosomes. Autophagic cell death is characterized by lack of chromatin condensation and massive vacuolization of the cytoplasm, with little or no uptake by phagocytic cells. GO:0000160 phosphorelay signal transduction system biolink:BiologicalProcess go-plus goslim_metagenomics http://purl.obolibrary.org/obo/GO_0000160 phosphorelay signal transduction system|histidyl-aspartyl phosphorelay A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins. CL:0011020 neural progenitor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0011020 An undifferentiated cell that originates from a neural stem cell and has the capacity to generate multiple types of lineage-restricted progenitors but not to self-renew. CHEBI:133452 (5R)-5-[(alpha-D-glucosyl-(1->2)-beta-D-galactosyl)oxy]-L-lysine(1+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133452 CHEBI:133455 (2E)-dec-2-enal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133455 CHEBI:133457 (3E)-3-nonen-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133457 CHEBI:133450 (2E)-enoyl-L-carnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133450 GO:0000178 exosome (RNase complex) biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0000178 exosome (ribonucleasease complex)|exosome multienzyme ribonuclease complex A ribonuclease complex that has 3-prime to 5-prime exoribonuclease activity and possibly endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured. GO:0048112 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048112 GO:0000177 cytoplasmic exosome (RNase complex) biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000177 prokaryotic exosome multienzyme ribonuclease complex|cytoplasmic exosome (ribonuclease complex)|cytoplasmic exosome multienzyme ribonuclease complex A ribonuclease complex that has 3-prime to 5-prime processive hydrolytic exoribonuclease activity producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured. GO:0048111 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048111 GO:0000176 nuclear exosome (RNase complex) biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000176 eukaryotic exosome multienzyme ribonuclease complex|nuclear exosome (ribonuclease complex)|nuclear exosome multienzyme ribonuclease complex A ribonuclease complex that has 3-prime to 5-prime processive and distributive hydrolytic exoribonuclease activity and endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured. GO:0048110 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048110 GO:0000175 3'-5'-exoribonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000175 Reactome:R-HSA-9694632|Reactome:R-HSA-6791222|EC:3.1.13.-|Reactome:R-HSA-430028|Reactome:R-HSA-6791227|Reactome:R-HSA-9682603 3'-5' exoribonuclease activity Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule. GO:1903519 regulation of mammary gland involution biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903519 Any process that modulates the frequency, rate or extent of mammary gland involution. GO:1903518 positive regulation of single strand break repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903518 up regulation of single strand break repair|upregulation of single strand break repair|up-regulation of single strand break repair|activation of single strand break repair Any process that activates or increases the frequency, rate or extent of single strand break repair. GO:1903517 negative regulation of single strand break repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903517 down-regulation of single strand break repair|downregulation of single strand break repair|down regulation of single strand break repair|inhibition of single strand break repair Any process that stops, prevents or reduces the frequency, rate or extent of single strand break repair. CHEBI:87251 monoacylglycerol 16:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87251 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000179 Reactome:R-HSA-6790994|Reactome:R-HSA-6793066 dimethyladenosine transferase activity|18S rRNA dimethylase activity|S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase activity Catalysis of the dimethylation of two adjacent adenine residues in a rRNA, using S-adenosyl-L-methionine as a methyl donor. GO:1903516 regulation of single strand break repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903516 Any process that modulates the frequency, rate or extent of single strand break repair. CL:0011016 flagellated sperm cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0011016 A motile sperm cell that contains a slender threadlike microscopic appendage that enables motion. GO:0000170 sphingosine hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000170 Reactome:R-HSA-428260 Catalysis of the hydroxylation of sphingolipid long chain bases. GO:1903515 calcium ion transport from cytosol to endoplasmic reticulum biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903515 The directed movement of calcium ion from cytosol to endoplasmic reticulum. GO:0048119 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048119 GO:1903514 release of sequestered calcium ion into cytosol by endoplasmic reticulum biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903514 calcium ion transport from endoplasmic reticulum to cytosol The directed movement of calcium ion from endoplasmic reticulum to cytosol. CL:0011015 amoeboid sperm cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0011015 A motile sperm cell that contain no F-actin, and their motility is powered by a dynamic filament system. GO:0048118 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048118 CHEBI:87255 monoacylglycerol 18:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87255 CL:0011014 non-motile sperm cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0011014 A sperm cell that is not cabaple of motion (motility). GO:1903513 endoplasmic reticulum to cytosol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903513 ER to cytosol transport The directed movement of substances from endoplasmic reticulum to cytosol. CL:0011013 motile sperm cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0011013 A sperm cell that is cabaple of motion (motility). GO:0048117 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048117 GO:1903512 phytanic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903512 phytanic acid metabolism The chemical reactions and pathways involving phytanic acid. GO:1903511 orotic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903511 orotic acid metabolism The chemical reactions and pathways involving orotic acid. CHEBI:87257 monoacylglycerol 18:2 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87257 GO:0000174 obsolete inactivation of MAPK (mating sensu Saccharomyces) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000174 inactivation of MAPK (mating sensu Saccharomyces) OBSOLETE. Downregulation of MAP kinase activity in the context of transduction of mating pheromone signal, as described for Saccharomyces. CL:0011012 neural crest cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0011012 A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells. GO:0048116 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048116 GO:1903510 mucopolysaccharide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903510 mucopolysaccharide metabolism The chemical reactions and pathways involving mucopolysaccharide. CHEBI:87256 monoacylglycerol 18:1 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87256 GO:0000173 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000173 GO:0048115 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048115 GO:0000172 ribonuclease MRP complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000172 RNase MRP complex|ribonuclease mitochondrial RNA processing complex A ribonucleoprotein complex that contains an RNA molecule of the snoRNA family, and cleaves the rRNA precursor as part of rRNA transcript processing. It also has other roles: In S. cerevisiae it is involved in cell cycle-regulated degradation of daughter cell-specific mRNAs, while in mammalian cells it also enters the mitochondria and processes RNAs to create RNA primers for DNA replication. CHEBI:87259 (E)-2-methylpentadec-2-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87259 GO:0048114 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048114 GO:0000171 ribonuclease MRP activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000171 Wikipedia:RNase_MRP RNase MRP Catalysis of the site-specific cleavage of RNA by a catalytic RNA-mediated mechanism; substrates include the A3 site in the ITS1 of pre-rRNA. GO:0048113 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048113 CL:0011019 mesothelial cell of epicardium biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0011019 A mesothelial cell that is part of the epicardium. GO:0000145 exocyst biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000145 Wikipedia:Exocyst exocyst complex|Sec6/8 complex A protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse. At least eight complex components are conserved between yeast and mammals. GO:0048123 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048123 GO:0048122 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048122 GO:0000144 cellular bud neck septin ring biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000144 A ring-shaped structure that forms at the site of cytokinesis in the bud neck of a budding cell; composed of members of the conserved family of filament forming proteins called septins as well as septin-associated proteins. In S. cerevisiae, this structure forms at the time of bud emergence and the septins show a high rate of exchange. GO:0000143 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000143 GO:0048121 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048121 GO:0000142 cellular bud neck contractile ring biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000142 neck ring A contractile ring, i.e. a cytoskeletal structure composed of actin filaments and myosin, that forms beneath the plasma membrane at the mother-bud neck in mitotic cells that divide by budding in preparation for completing cytokinesis. An example of this structure is found in Saccharomyces cerevisiae. GO:0048120 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048120 GO:0000149 SNARE binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0000149 Reactome:R-HSA-210430|Reactome:R-HSA-376364|Reactome:R-HSA-380905|Reactome:R-HSA-9023173|Reactome:R-HSA-374899|Reactome:R-HSA-380901|Reactome:R-HSA-380869|Reactome:R-HSA-888589|Reactome:R-HSA-210426|Reactome:R-HSA-372505|Reactome:R-HSA-917744|Reactome:R-HSA-374922|Reactome:R-HSA-265166|Reactome:R-HSA-376357|Reactome:R-HSA-376369|Reactome:R-HSA-372529|Reactome:R-HSA-380574 SNAP receptor binding Interacting selectively and non-covalently with a SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) protein. GO:1903529 negative regulation of dCDP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903529 down-regulation of dCDP anabolism|negative regulation of dCDP anabolism|down-regulation of dCDP synthesis|negative regulation of dCDP synthesis|inhibition of dCDP biosynthetic process|inhibition of dCDP biosynthesis|down-regulation of dCDP formation|negative regulation of dCDP formation|downregulation of dCDP anabolism|down regulation of dCDP anabolism|downregulation of dCDP synthesis|inhibition of dCDP anabolism|downregulation of dCDP formation|down regulation of dCDP biosynthesis|down regulation of dCDP synthesis|down regulation of dCDP biosynthetic process|inhibition of dCDP synthesis|down regulation of dCDP formation|downregulation of dCDP biosynthetic process|downregulation of dCDP biosynthesis|inhibition of dCDP formation|down-regulation of dCDP biosynthetic process|down-regulation of dCDP biosynthesis|negative regulation of dCDP biosynthesis Any process that stops, prevents or reduces the frequency, rate or extent of dCDP biosynthetic process. GO:0000148 1,3-beta-D-glucan synthase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000148 (1->3)-beta-glucan synthase complex|1,3-beta-glucan synthase complex A protein complex that catalyzes the transfer of a glucose group from UDP-glucose to a (1->3)-beta-D-glucan chain. GO:0000147 actin cortical patch assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000147 Assembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane of fungal cells. GO:1903528 regulation of dCDP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903528 regulation of dCDP anabolism|regulation of dCDP synthesis|regulation of dCDP formation|regulation of dCDP biosynthesis Any process that modulates the frequency, rate or extent of dCDP biosynthetic process. GO:1903527 positive regulation of membrane tubulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903527 upregulation of membrane tubulation|upregulation of plasma membrane tubulation|up regulation of membrane tubulation|activation of plasma membrane tubulation|up-regulation of plasma membrane tubulation|activation of membrane tubulation|positive regulation of plasma membrane tubulation|up-regulation of membrane tubulation|up regulation of plasma membrane tubulation Any process that activates or increases the frequency, rate or extent of membrane tubulation. GO:0000146 microfilament motor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000146 Reactome:R-HSA-9023171|Reactome:R-HSA-2316352|Reactome:R-HSA-432237 actin filament motor activity|muscle motor activity|actin-filament motor activity|myosin ATPase activity Catalysis of movement along a microfilament, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP). GO:1903526 negative regulation of membrane tubulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903526 down regulation of plasma membrane tubulation|inhibition of plasma membrane tubulation|down regulation of membrane tubulation|downregulation of membrane tubulation|down-regulation of membrane tubulation|down-regulation of plasma membrane tubulation|negative regulation of plasma membrane tubulation|inhibition of membrane tubulation|downregulation of plasma membrane tubulation Any process that stops, prevents or reduces the frequency, rate or extent of membrane tubulation. CL:0011005 GABAergic interneuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0011005 GABAergic inhibitory interneuron An interneuron that uses GABA as a vesicular neurotransmitter. These interneurons are inhibitory GO:1903525 regulation of membrane tubulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903525 regulation of plasma membrane tubulation|regulation of vesicle scission Any process that modulates the frequency, rate or extent of membrane tubulation. CL:0011004 lens fiber cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0011004 lens fibre cell A vetebrate lens cell that is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye. GO:1903524 positive regulation of blood circulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903524 up-regulation of blood circulation|activation of hemolymph circulation|up-regulation of hemolymph circulation|upregulation of blood circulation|upregulation of hemolymph circulation|up regulation of blood circulation|activation of blood circulation|up regulation of hemolymph circulation|positive regulation of hemolymph circulation Any process that activates or increases the frequency, rate or extent of blood circulation. GO:0048129 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048129 GO:1903523 negative regulation of blood circulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903523 down-regulation of hemolymph circulation|negative regulation of hemolymph circulation|inhibition of blood circulation|inhibition of hemolymph circulation|down regulation of blood circulation|downregulation of blood circulation|down regulation of hemolymph circulation|downregulation of hemolymph circulation|down-regulation of blood circulation Any process that stops, prevents or reduces the frequency, rate or extent of blood circulation. CL:0011002 lateral motor column neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0011002 A motor neuron that is generated only on limb levels and send axons into the limb mesenchyme. GO:0048128 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048128 CHEBI:87287 4beta-methylzymosterol-4-carbaldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87287 CL:0011001 spinal cord motor neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0011001 A motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement. GO:0000141 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000141 GO:1903522 regulation of blood circulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903522 regulation of hemolymph circulation Any process that modulates the frequency, rate or extent of blood circulation. GO:0048127 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048127 GO:1903521 positive regulation of mammary gland involution biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903521 activation of mammary gland involution|up-regulation of mammary gland involution|up regulation of mammary gland involution|upregulation of mammary gland involution Any process that activates or increases the frequency, rate or extent of mammary gland involution. GO:0048126 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048126 GO:0000140 acylglycerone-phosphate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000140 RHEA:17341|Reactome:R-HSA-75883|MetaCyc:ACYLGLYCERONE-PHOSPHATE-REDUCTASE-RXN|EC:1.1.1.101 1-acyldihydroxyacetone-phosphate reductase activity|acyldihydroxyacetone phosphate reductase activity|palmitoyldihydroxyacetone-phosphate reductase activity|palmitoyl dihydroxyacetone phosphate reductase activity|palmitoyl-dihydroxyacetone-phosphate reductase activity|1-palmitoylglycerol-3-phosphate:NADP+ oxidoreductase activity Catalysis of the reaction: 1-palmitoylglycerol-3-phosphate + NADP+ = palmitoylglycerone phosphate + NADPH + H(+). CL:0011000 dorsal horn interneuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0011000 dorsal spinal cord interneuron A CNS interneuron located in the dorsal horn of the spinal cord. CHEBI:87289 4alpha-hydroxymethyl-4beta-methylzymosterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87289 GO:1903520 negative regulation of mammary gland involution biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903520 down-regulation of mammary gland involution|downregulation of mammary gland involution|down regulation of mammary gland involution|inhibition of mammary gland involution Any process that stops, prevents or reduces the frequency, rate or extent of mammary gland involution. GO:0048125 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048125 GO:0048124 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048124 PR:000001489 neuromedin-U receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001489 neuromedin U receptor|fam:NMU_R A rhodopsin-like G-protein coupled receptor that is a translation product of the human NMUR1 or NMUR2 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. PR:000001488 muscarinic acetylcholine receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001488 A rhodopsin-like G-protein coupled receptor that is a translation product of the human CHRM1 to CHRM5 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. CL:0011006 Lugaro cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0011006 An inhibitory GABAergic interneuron found in the cerebellar cortex. GO:0048134 germ-line cyst formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048134 germline cyst formation Formation of a group of interconnected cells derived from a single gonial founder cell. GO:0000156 phosphorelay response regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000156 two-component response regulator activity Responds to a phosphorelay sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response. GO:0048133 male germ-line stem cell asymmetric division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048133 male germ-line stem cell renewal The self-renewing division of a germline stem cell in the male gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the male gametes. GO:0000155 phosphorelay sensor kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000155 EC:2.7.3.- two-component sensor activity|two-component sensor molecule|two-component system sensor activity Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response. GO:0000154 rRNA modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000154 rRNA editing The covalent alteration of one or more nucleotides within an rRNA molecule to produce an rRNA molecule with a sequence that differs from that coded genetically. GO:0048132 female germ-line stem cell asymmetric division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048132 female germ-line stem cell renewal The self-renewing division of a germline stem cell in the female gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the female gametes. GO:0000153 cytoplasmic ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000153 A ubiquitin ligase complex found in the cytoplasm. GO:0048131 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048131 GO:0048130 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048130 GO:0000159 protein phosphatase type 2A complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000159 protein phosphatase 2 complex A protein complex that has protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic, scaffolding, and regulatory subunits. The catalytic and scaffolding subunits form the core enzyme, and the holoenzyme also includes the regulatory subunit. GO:0000158 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000158 GO:1903539 protein localization to postsynaptic membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903539 protein localization in postsynaptic membrane|protein localisation in postsynaptic membrane|protein localisation to postsynaptic membrane A process in which a protein is transported to, or maintained in, a location within a postsynaptic membrane. GO:1903538 regulation of meiotic cell cycle process involved in oocyte maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903538 regulation of meiosis involved in oocyte maturation Any process that modulates the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation. GO:0000157 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000157 GO:1903537 meiotic cell cycle process involved in oocyte maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903537 meiosis involved in oocyte maturation Any meiotic cell cycle process that is involved in oocyte maturation. GO:1903536 positive regulation of lactose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903536 up-regulation of lactose anabolism|positive regulation of lactose biosynthesis|up-regulation of lactose synthesis|up regulation of lactose biosynthetic process|up regulation of lactose biosynthesis|up-regulation of lactose formation|upregulation of lactose anabolism|upregulation of lactose synthesis|upregulation of lactose biosynthetic process|upregulation of lactose biosynthesis|upregulation of lactose formation|up regulation of lactose anabolism|activation of lactose anabolism|positive regulation of lactose anabolism|up regulation of lactose synthesis|up-regulation of lactose biosynthetic process|up-regulation of lactose biosynthesis|activation of lactose synthesis|positive regulation of lactose synthesis|activation of lactose biosynthesis|activation of lactose biosynthetic process|up regulation of lactose formation|activation of lactose formation|positive regulation of lactose formation Any process that activates or increases the frequency, rate or extent of lactose biosynthetic process. CHEBI:133449 hydroxy-fatty acyl-L-carnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133449 GO:1903535 negative regulation of lactose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903535 negative regulation of lactose formation|down-regulation of lactose formation|inhibition of lactose synthesis|inhibition of lactose formation|downregulation of lactose biosynthetic process|downregulation of lactose biosynthesis|down regulation of lactose biosynthesis|down regulation of lactose biosynthetic process|down regulation of lactose anabolism|inhibition of lactose biosynthesis|inhibition of lactose biosynthetic process|downregulation of lactose anabolism|down regulation of lactose synthesis|down regulation of lactose formation|downregulation of lactose synthesis|downregulation of lactose formation|negative regulation of lactose anabolism|down-regulation of lactose anabolism|negative regulation of lactose synthesis|down-regulation of lactose synthesis|inhibition of lactose anabolism|negative regulation of lactose biosynthesis|down-regulation of lactose biosynthesis|down-regulation of lactose biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of lactose biosynthetic process. CHEBI:87277 3beta-hydroxy-4beta-methyl-5alpha-cholest-8-ene-4alpha-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87277 GO:1903534 regulation of lactose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903534 regulation of lactose biosynthesis|regulation of lactose anabolism|regulation of lactose synthesis|regulation of lactose formation Any process that modulates the frequency, rate or extent of lactose biosynthetic process. GO:0048139 female germ-line cyst encapsulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048139 Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the female gonad. GO:0000152 nuclear ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000152 A ubiquitin ligase complex found in the nucleus. GO:1903533 regulation of protein targeting biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903533 regulation of protein sorting along secretory pathway|regulation of nascent polypeptide association Any process that modulates the frequency, rate or extent of protein targeting. GO:0048138 germ-line cyst encapsulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048138 Formation of a single follicular epithelium around the germ-line derived cells of a cyst. GO:1903532 positive regulation of secretion by cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903532 up regulation of secretion by cell|activation of secretion by cell|up-regulation of cellular secretion|activation of cellular secretion|up-regulation of secretion by cell|positive regulation of cellular secretion|up regulation of cellular secretion|upregulation of secretion by cell|upregulation of cellular secretion Any process that activates or increases the frequency, rate or extent of secretion by cell. GO:0048137 spermatocyte division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048137 spermatocyte cell division The meiotic divisions undergone by the primary and secondary spermatocytes to produce haploid spermatids. GO:0000151 ubiquitin ligase complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0000151 A protein complex that includes a ubiquitin-protein ligase and enables ubiquitin protein ligase activity. The complex also contains other proteins that may confer substrate specificity on the complex. GO:1903531 negative regulation of secretion by cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903531 down-regulation of secretion by cell|down-regulation of cellular secretion|negative regulation of cellular secretion|inhibition of secretion by cell|downregulation of cellular secretion|down regulation of cellular secretion|down regulation of secretion by cell|inhibition of cellular secretion|downregulation of secretion by cell Any process that stops, prevents or reduces the frequency, rate or extent of secretion by cell. GO:0048136 male germ-line cyst formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048136 male germline cyst formation Formation of a group of interconnected cells derived from a single male gonial founder cell. GO:0000150 recombinase activity biolink:MolecularActivity go-plus goslim_metagenomics http://purl.obolibrary.org/obo/GO_0000150 Reactome:R-HSA-912458 strand transferase Catalysis of the identification and base-pairing of homologous sequences between single-stranded DNA and double-stranded DNA. GO:0048135 female germ-line cyst formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048135 female germline cyst formation Formation of a group of interconnected cells derived from a single female gonial founder cell. GO:1903530 regulation of secretion by cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903530 regulation of cellular secretion Any process that modulates the frequency, rate or extent of secretion by cell. GO:1903540 establishment of protein localization to postsynaptic membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903540 establishment of protein localisation to postsynaptic membrane|establishment of protein localization in postsynaptic membrane|establishment of protein localisation in postsynaptic membrane The directed movement of a protein to a specific location in a postsynaptic membrane. CHEBI:133442 (5R)-5-hydroxy-L-lysine(1+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133442 CHEBI:133444 1-O-acylceramide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133444 CHEBI:133443 (5R)-5-(beta-D-galactosyloxy)-L-lysine(1+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133443 PR:000001498 pyroglutamylated RF-amide peptide receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001498 GPR103|SP9155|AQ27|orexigenic neuropeptide QRFP receptor|G-protein coupled receptor 103|QRFPR A rhodopsin-like G-protein coupled receptor that is a translation product of the human QRFPR gene or a 1:1 ortholog thereof. CHEBI:133446 monounsaturated fatty acyl-L-carnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133446 PR:000001497 opioid receptor protein biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001497 A rhodopsin-like G-protein coupled receptor that is a translation product of the human OPRD1, OPRK1, OPRM1, or OPRL1 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. CHEBI:133445 saturated fatty acyl-L-carnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133445 CHEBI:133448 oxo-fatty acyl-L-carnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133448 PR:000001499 orexin receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001499 hypocretin receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human HCRTR1 or HCRTR2 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. CHEBI:133447 methyl-branched fatty acyl-L-carnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133447 GO:0000123 histone acetyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000123 histone acetylase complex A protein complex that possesses histone acetyltransferase activity. GO:0048145 regulation of fibroblast proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048145 Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells. GO:0000122 negative regulation of transcription by RNA polymerase II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000122 down-regulation of global transcription from RNA polymerase II promoter|negative regulation of transcription from Pol II promoter|negative regulation of global transcription from Pol II promoter|inhibition of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter, global|downregulation of global transcription from RNA polymerase II promoter|down regulation of global transcription from RNA polymerase II promoter|down regulation of transcription from RNA polymerase II promoter|downregulation of transcription from RNA polymerase II promoter|inhibition of global transcription from RNA polymerase II promoter|negative regulation of gene-specific transcription from RNA polymerase II promoter|down-regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. GO:0048144 fibroblast proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048144 The multiplication or reproduction of fibroblast cells, resulting in the expansion of the fibroblast population. GO:0000121 glycerol-1-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000121 EC:3.1.3.21|RHEA:11476|MetaCyc:GLYCEROL-1-PHOSPHATASE-RXN glycerol-3-phosphate phosphatase activity|glycerol 3-phosphate phosphohydrolase activity|alpha-glycerophosphatase activity|glycerol 3-phosphatase activity|glycerol-1-phosphate phosphohydrolase activity|alpha-glycerol phosphatase activity Catalysis of the reaction: glycerol-1-phosphate + H2O = glycerol + phosphate. GO:0048143 astrocyte activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048143 A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. GO:0048142 germarium-derived cystoblast division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048142 germarium-derived cystoblast cell division The four rounds of incomplete mitosis undergone by a cystoblast to form a 16-cell cyst of interconnected cells within a germarium. Within the cyst, one cell differentiates into an oocyte while the rest become nurse cells. An example of this process is found in Drosophila melanogaster. GO:0000120 RNA polymerase I transcription regulator complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000120 RNA polymerase I transcription factor complex A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase I. GO:0048141 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048141 GO:0000127 transcription factor TFIIIC complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000127 A heterotrimeric transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIC contains three conserved subunits that associate with the proximal Pol III promoter element, and additional subunits that associate with sequence elements downstream of the promoter and are more diverged among species. It also functions as a boundary element to partition genome content into distinct domains outside Pol III promoter regions. GO:0048140 male germ-line cyst encapsulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048140 Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the male gonad. GO:0000126 transcription factor TFIIIB complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000126 A transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIB contains the TATA-binding protein (TBP) and two Pol III-specific proteins, B'' and BRF. GO:0000125 PCAF complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000125 PCAF histone acetylase-associated complex|SPT3-TAF9-PCAF acetylase complex A large multiprotein complex that possesses histone acetyltransferase activity and is involved in regulation of transcription. The composition is similar to that of the SAGA complex, but includes fewer Spt and Ada proteins, and more TAFs. CHEBI:38291 dihydrostreptomycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38291 GO:1903549 positive regulation of growth hormone activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903549 up-regulation of placental growth hormone activity|upregulation of growth hormone activity|up regulation of GH activity|up regulation of pituitary growth hormone activity|activation of GH activity|positive regulation of GH activity|upregulation of placental growth hormone activity|positive regulation of pituitary growth hormone activity|activation of pituitary growth hormone activity|up regulation of growth hormone activity|activation of growth hormone activity|up regulation of placental growth hormone activity|up-regulation of GH activity|up-regulation of pituitary growth hormone activity|positive regulation of placental growth hormone activity|activation of placental growth hormone activity|upregulation of GH activity|up-regulation of growth hormone activity|upregulation of pituitary growth hormone activity Any process that activates or increases the frequency, rate or extent of growth hormone activity. GO:0000124 SAGA complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000124 Spt-Ada-Gcn5-acetyltransferase complex A SAGA-type histone acetyltransferase complex that contains Spt8 (in budding yeast) or a homolog thereof; additional polypeptides include Spt group, consisting of Spt7, Spt3, and Spt20/Ada5, which interact with the TATA-binding protein (TBP); the Ada group, consisting of Ada1, Ada2, Ada3, Ada4/Gcn5, and Ada5/Spt20, which is functionally linked to the nucleosomal HAT activity; Tra1, an ATM/PI-3 kinase-related protein that targets DNA-bound activators for recruitment to promoters; the TBP-associated factor (TAF) proteins, consisting of Taf5, Taf6, Taf9, Taf10, and Taf12, which mediate nucleosomal HAT activity and are thought to help recruit the basal transcription machinery; the ubiquitin specifc protease Ubp-8. CHEBI:38290 L-ascorbate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38290 GO:1903548 negative regulation of growth hormone activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903548 down regulation of GH activity|down regulation of pituitary growth hormone activity|downregulation of GH activity|inhibition of placental growth hormone activity|downregulation of pituitary growth hormone activity|down regulation of growth hormone activity|down regulation of placental growth hormone activity|down-regulation of GH activity|negative regulation of GH activity|downregulation of growth hormone activity|down-regulation of pituitary growth hormone activity|negative regulation of pituitary growth hormone activity|downregulation of placental growth hormone activity|inhibition of GH activity|down-regulation of growth hormone activity|negative regulation of placental growth hormone activity|down-regulation of placental growth hormone activity|inhibition of pituitary growth hormone activity|inhibition of growth hormone activity Any process that stops, prevents or reduces the frequency, rate or extent of growth hormone activity. CHEBI:133417 O-[S-(18-carbamoyl-3,5,7,9,11,13,15,17-octaoxooctadecanoyl)pantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133417 GO:1903547 regulation of growth hormone activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903547 regulation of GH activity|regulation of pituitary growth hormone activity|regulation of placental growth hormone activity Any process that modulates the frequency, rate or extent of growth hormone activity. GO:1903546 protein localization to photoreceptor outer segment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903546 protein localisation to photoreceptor outer segment|protein localization in photoreceptor outer segment|protein localisation in photoreceptor outer segment A process in which a protein is transported to, or maintained in, a location within a photoreceptor outer segment. CHEBI:133419 2-isobutyrylphloroglucinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133419 GO:1903545 cellular response to butyrate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903545 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butyrate stimulus. CL:0001658 visual pigment cell (sensu Nematoda and Protostomia) biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001658 GO:1903544 response to butyrate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903544 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butyrate stimulus. GO:0048149 behavioral response to ethanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048149 behavioural response to ethanol Any process that results in a change in the behavior of an organism as a result of an ethanol stimulus. GO:1903543 positive regulation of exosomal secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903543 positive regulation of exosomal protein secretion|upregulation of extracellular vesicular exosome secretion|up regulation of exosomal protein secretion|activation of exosomal secretory pathway|up-regulation of exosomal secretory pathway|up-regulation of secretion of exosome|activation of secretion of exosome|up regulation of extracellular vesicular exosome secretion|up regulation of exosomal secretion|upregulation of exosomal protein secretion|activation of extracellular vesicular exosome secretion|positive regulation of extracellular vesicular exosome secretion|positive regulation of exosomal secretory pathway|positive regulation of secretion of exosome|up regulation of exosomal secretory pathway|up regulation of secretion of exosome|up-regulation of exosomal protein secretion|upregulation of exosomal secretion|up-regulation of extracellular vesicular exosome secretion|activation of exosomal protein secretion|upregulation of exosomal secretory pathway|upregulation of secretion of exosome|up-regulation of exosomal secretion|activation of exosomal secretion Any process that activates or increases the frequency, rate or extent of exosomal secretion. GO:0048148 behavioral response to cocaine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048148 behavioural response to cocaine Any process that results in a change in the behavior of an organism as a result of a cocaine stimulus. GO:1903542 negative regulation of exosomal secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903542 down regulation of extracellular vesicular exosome secretion|down-regulation of exosomal secretion|downregulation of exosomal protein secretion|downregulation of extracellular vesicular exosome secretion|down regulation of exosomal protein secretion|down-regulation of exosomal secretory pathway|negative regulation of exosomal secretory pathway|negative regulation of secretion of exosome|downregulation of exosomal secretion|down-regulation of secretion of exosome|negative regulation of extracellular vesicular exosome secretion|inhibition of exosomal protein secretion|down-regulation of extracellular vesicular exosome secretion|down regulation of exosomal secretion|inhibition of exosomal secretion|downregulation of exosomal secretory pathway|downregulation of secretion of exosome|inhibition of extracellular vesicular exosome secretion|down regulation of exosomal secretory pathway|down regulation of secretion of exosome|inhibition of exosomal secretory pathway|inhibition of secretion of exosome|negative regulation of exosomal protein secretion|down-regulation of exosomal protein secretion Any process that stops, prevents or reduces the frequency, rate or extent of exosomal secretion. GO:0048147 negative regulation of fibroblast proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048147 down-regulation of fibroblast proliferation|downregulation of fibroblast proliferation|down regulation of fibroblast proliferation|inhibition of fibroblast proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells. GO:0048146 positive regulation of fibroblast proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048146 activation of fibroblast proliferation|up regulation of fibroblast proliferation|upregulation of fibroblast proliferation|stimulation of fibroblast proliferation|up-regulation of fibroblast proliferation Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells. GO:1903541 regulation of exosomal secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903541 regulation of extracellular vesicular exosome secretion|regulation of exosomal protein secretion|regulation of exosomal secretory pathway|regulation of secretion of exosome Any process that modulates the frequency, rate or extent of exosomal secretion. GO:1903551 regulation of extracellular exosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903551 regulation of extracellular vesicular exosome assembly Any process that modulates the frequency, rate or extent of extracellular vesicular exosome assembly. CHEBI:133411 13,14-dihydro-15-keto-PGF1alpha(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133411 CHEBI:133415 O-(S-malonamoylpantetheine-4'-phosphoryl)serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133415 CHEBI:133414 N-acetyl-L-methionyl residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133414 GO:0000129 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000129 GO:0000128 flocculation biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0000128 Wikipedia:Flocculation coflocculation via lectin-mannose interaction|co-flocculation|cell-cell adhesion involved in flocculation|cell-cell adhesion involved in flocculation via cell wall protein-carbohydrate interaction|coflocculation|flocculation via extracellular polymer|coflocculation via protein-carbohydrate interaction|flocculation via cell wall protein-carbohydrate interaction The reversible, non-sexual aggregation of single-celled organisms in suspension to form aggregates of many cells known as flocs. GO:0000134 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000134 GO:0048156 tau protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048156 Interacting selectively and non-covalently with tau protein. tau is a microtubule-associated protein, implicated in Alzheimer's disease, Down Syndrome and ALS. GO:0000133 polarisome biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0000133 Protein complex that plays a role in determining cell polarity by directing the localized assembly of actin filaments at polarization sites; in Saccharomyces the polarisome includes Bni1p, Spa2p, Pea2p, and Bud6p. GO:0048155 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048155 GO:0000132 establishment of mitotic spindle orientation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000132 establishment of spindle orientation during mitosis|mitotic spindle orientation|establishment of spindle orientation involved in mitotic cell cycle|orienting of mitotic spindle A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures. GO:0048154 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048154 GO:0048153 obsolete S100 alpha biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048153 S100 alpha anabolism|S100 alpha biosynthesis|S100 alpha synthesis|S100 alpha formation OBSOLETE. The chemical reactions and pathways resulting in the formation of S100 alpha protein. S100 is a small calcium and zinc binding protein produced in astrocytes that is implicated in Alzheimer's disease, Down Syndrome and ALS. GO:0000131 incipient cellular bud site biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000131 The portion of the budding yeast plasma membrane where a daughter cell will emerge. The yeast marks this spot with bud-site selection proteins before bud emergence occurs. Actin is polarized to this spot just prior to and during bud emergence. GO:0000138 Golgi trans cisterna biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000138 late Golgi The Golgi cisterna farthest from the endoplasmic reticulum; the final processing compartment through which proteins pass before exiting the Golgi apparatus; the compartment in which N-linked protein glycosylation is completed. GO:0048152 obsolete S100 beta biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048152 S100 beta anabolism|S100 beta synthesis|S100 beta formation|S100 beta biosynthesis OBSOLETE. The chemical reactions and pathways resulting in the formation of S100 beta protein. S100 is a small calcium and zinc binding protein produced in astrocytes that is implicated in Alzheimer's disease, Down Syndrome and ALS. CHEBI:87293 3beta-hydroxy-5alpha-cholest-8-ene-4alpha-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87293 GO:0000137 Golgi cis cisterna biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000137 The Golgi cisterna closest to the endoplasmic reticulum; the first processing compartment through which proteins pass after export from the ER. GO:0048151 obsolete hyperphosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048151 hyperphosphorylation OBSOLETE. The excessive phosphorylation of a protein, as a result of activation of kinases, deactivation of phosphatases, or both. GO:0000136 mannan polymerase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000136 alpha-1,6-mannosyltransferase complex A protein complex with alpha-(1->6)-mannosyltransferase activity, located in the cis Golgi membrane; adds mannan to N-linked glycans on proteins. GO:0048150 behavioral response to ether biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048150 behavioural response to ether Any process that results in a change in the behavior of an organism as a result of an ether stimulus. GO:0000135 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000135 GO:1903559 3-cyano-L-alanine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903559 3-cyano-L-alanine catabolism|3-cyano-L-alanine degradation|3-cyano-L-alanine breakdown The chemical reactions and pathways resulting in the breakdown of 3-cyano-L-alanine. GO:1903558 3-cyano-L-alanine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903558 3-cyano-L-alanine metabolism The chemical reactions and pathways involving 3-cyano-L-alanine. CHEBI:133427 omega-ammonioaldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133427 GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903557 activation of TNF superfamily production|up regulation of tumor necrosis factor superfamily cytokine production|upregulation of TNFSF cytokine production|activation of tumor necrosis factor superfamily cytokine production|positive regulation of TNF superfamily production|up regulation of TNF superfamily production|up regulation of TNFSF cytokine production|activation of TNFSF cytokine production|positive regulation of TNFSF cytokine production|up-regulation of tumor necrosis factor superfamily cytokine production|upregulation of TNF superfamily production|upregulation of tumor necrosis factor superfamily cytokine production|up-regulation of TNF superfamily production|up-regulation of TNFSF cytokine production Any process that activates or increases the frequency, rate or extent of tumor necrosis factor superfamily cytokine production. GO:1903556 negative regulation of tumor necrosis factor superfamily cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903556 downregulation of tumor necrosis factor superfamily cytokine production|down-regulation of TNF superfamily production|negative regulation of TNF superfamily production|down regulation of TNFSF cytokine production|down-regulation of tumor necrosis factor superfamily cytokine production|downregulation of TNF superfamily production|downregulation of TNFSF cytokine production|down regulation of TNF superfamily production|inhibition of tumor necrosis factor superfamily cytokine production|negative regulation of TNFSF cytokine production|down-regulation of TNFSF cytokine production|inhibition of TNF superfamily production|inhibition of TNFSF cytokine production|down regulation of tumor necrosis factor superfamily cytokine production Any process that stops, prevents or reduces the frequency, rate or extent of tumor necrosis factor superfamily cytokine production. GO:1903555 regulation of tumor necrosis factor superfamily cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903555 regulation of TNFSF cytokine production|regulation of TNF superfamily production Any process that modulates the frequency, rate or extent of tumor necrosis factor superfamily cytokine production. GO:0000130 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000130 GO:1903554 G protein-coupled receptor signaling pathway involved in defense response to Gram-negative bacterium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903554 G-protein coupled receptor protein signaling pathway involved in defense response to Gram-negative bacterium|G-protein coupled receptor protein signal transduction involved in Gram-negative antibacterial peptide activity|GPCR signalling pathway involved in defence response to Gram-negative bacterium|G-protein-coupled receptor protein signaling pathway involved in defence response to Gram-negative bacterium|GPCR signaling pathway involved in defence response to Gram-negative bacteria|G protein coupled receptor protein signaling pathway involved in Gram-negative antibacterial peptide activity|G-protein-coupled receptor protein signalling pathway involved in defence response to Gram-negative bacteria|G-protein coupled receptor signalling pathway involved in defense response to Gram-negative bacteria|G-protein-coupled receptor protein signalling pathway involved in defense response to Gram-negative bacterium|G protein coupled receptor protein signalling pathway involved in Gram-negative antibacterial peptide activity|G-protein coupled receptor signalling pathway involved in defence response to Gram-negative bacterium|GPCR signaling pathway involved in defense response to Gram-negative bacterium|G-protein coupled receptor signaling pathway involved in defence response to Gram-negative bacteria|GPCR signalling pathway involved in defense response to Gram-negative bacteria|G-protein coupled receptor protein signaling pathway involved in defence response to Gram-negative bacteria|GPCR signaling pathway involved in Gram-negative antibacterial peptide activity|G protein coupled receptor protein signalling pathway involved in defense response to Gram-negative bacterium|G-protein coupled receptor protein signal transduction involved in defense response to Gram-negative bacteria|G-protein-coupled receptor protein signalling pathway involved in Gram-negative antibacterial peptide activity|G protein coupled receptor protein signaling pathway involved in defense response to Gram-negative bacteria|G protein coupled receptor protein signaling pathway involved in defense response to Gram-negative bacterium|G-protein coupled receptor signaling pathway involved in Gram-negative antibacterial peptide activity|G protein coupled receptor protein signalling pathway involved in defense response to Gram-negative bacteria|G-protein coupled receptor protein signal transduction involved in defense response to Gram-negative bacterium|G-protein coupled receptor protein signaling pathway involved in Gram-negative antibacterial peptide activity|G-protein coupled receptor protein signaling pathway involved in defence response to Gram-negative bacterium|GPCR signalling pathway involved in defense response to Gram-negative bacterium|G-protein coupled receptor signaling pathway involved in defence response to Gram-negative bacterium|GPCR signaling pathway involved in defense response to Gram-negative bacteria|G-protein-coupled receptor protein signaling pathway involved in defense response to Gram-negative bacterium|G-protein coupled receptor signalling pathway involved in defence response to Gram-negative bacteria|G-protein-coupled receptor protein signalling pathway involved in defense response to Gram-negative bacteria|G-protein coupled receptor signalling pathway involved in defense response to Gram-negative bacterium|G-protein-coupled receptor protein signalling pathway involved in defence response to Gram-negative bacterium|G-protein coupled receptor signaling pathway involved in defense response to Gram-negative bacteria|G-protein-coupled receptor protein signaling pathway involved in defence response to Gram-negative bacteria|GPCR signaling pathway involved in defence response to Gram-negative bacterium|GPCR signalling pathway involved in defence response to Gram-negative bacteria|G-protein coupled receptor protein signaling pathway involved in defense response to Gram-negative bacteria|G protein coupled receptor protein signalling pathway involved in defence response to Gram-negative bacterium|G-protein coupled receptor protein signal transduction involved in defence response to Gram-negative bacteria|G-protein coupled receptor signalling pathway involved in Gram-negative antibacterial peptide activity|G protein coupled receptor protein signaling pathway involved in defence response to Gram-negative bacteria|G protein coupled receptor protein signaling pathway involved in defence response to Gram-negative bacterium|G-protein-coupled receptor protein signaling pathway involved in Gram-negative antibacterial peptide activity|G protein coupled receptor protein signalling pathway involved in defence response to Gram-negative bacteria|G-protein coupled receptor protein signal transduction involved in defence response to Gram-negative bacterium|GPCR signalling pathway involved in Gram-negative antibacterial peptide activity Any G protein-coupled receptor signaling pathway that is involved in defense response to Gram-negative bacterium. GO:0048159 primary oocyte stage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048159 mammalian oogenesis stage 2 The stage in oogenesis when the oocyte has a nucleus slightly larger than those of the adjacent cells and is surrounded by a layer of loose squamous epithelial cells. GO:1903553 positive regulation of extracellular exosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903553 upregulation of extracellular vesicular exosome assembly|up-regulation of extracellular vesicular exosome assembly|activation of extracellular vesicular exosome assembly|positive regulation of extracellular vesicular exosome assembly|up regulation of extracellular vesicular exosome assembly Any process that activates or increases the frequency, rate or extent of extracellular vesicular exosome assembly. GO:0048158 oogonium stage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048158 mammalian oogenesis stage 1 The stage in mammalian oogenesis when the primordial germ cell is hardly distinguishable from other cortical cells of the ovary. GO:1903552 negative regulation of extracellular exosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903552 down regulation of extracellular vesicular exosome assembly|inhibition of extracellular vesicular exosome assembly|negative regulation of extracellular vesicular exosome assembly|down-regulation of extracellular vesicular exosome assembly|downregulation of extracellular vesicular exosome assembly Any process that stops, prevents or reduces the frequency, rate or extent of extracellular vesicular exosome assembly. GO:0048157 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048157 GO:1903562 microtubule bundle formation involved in mitotic spindle midzone assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903562 microtubule bundle formation involved in mitotic spindle midzone formation|microtubule bundle formation involved in spindle midzone assembly involved in mitosis|microtubule bundling involved in mitotic spindle midzone assembly|microtubule bundling involved in spindle midzone formation involved in mitosis|microtubule bundling involved in spindle midzone assembly involved in mitosis|microtubule bundling involved in spindle midzone biogenesis involved in mitosis|microtubule bundling involved in mitotic spindle midzone formation|microtubule bundle formation involved in mitotic spindle midzone assembly Any microtubule bundle formation that is involved in spindle midzone assembly involved in mitosis. GO:1903561 extracellular vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1903561 microparticle Any vesicle that is part of the extracellular region. GO:1903560 3-cyano-L-alanine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903560 3-cyano-L-alanine anabolism|3-cyano-L-alanine biosynthesis|3-cyano-L-alanine synthesis|3-cyano-L-alanine formation The chemical reactions and pathways resulting in the formation of 3-cyano-L-alanine. CHEBI:133421 prostaglandin F1alpha (1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133421 CHEBI:133424 13,14-dihydro-Delta(12)-prostaglandin J2(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133424 CHEBI:38297 thiabicycloalkane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38297 CHEBI:38295 azabicycloalkane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38295 GO:0000139 Golgi membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000139 The lipid bilayer surrounding any of the compartments of the Golgi apparatus. CHEBI:38299 vernolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38299 CHEBI:38298 benzodioxoles biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38298 GO:0000101 sulfur amino acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000101 sulphur amino acid transport The directed movement of amino acids containing sulfur (cystine, methionine and their derivatives) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0048167 regulation of synaptic plasticity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048167 A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers. GO:0000100 S-methylmethionine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000100 S-methylmethionine transporter activity|S-methylmethionine permease activity Enables the transfer of S-methylmethionine from one side of a membrane to the other. GO:0048166 mature follicle stage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048166 mammalian oogenesis stage 9 The stage in oogenesis when the antrum is swollen with follicular fluid. The ovum is ready to erupt from the ovary and is arrested at metaphase of the second meiotic division. GO:0048165 fused antrum stage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048165 mammalian oogenesis stage 8 The stage in oogenesis when the antral spaces fuse to form a single antral space. The oocyte is suspended in the cumulus oophorous and the first polar body in the perivitelline space. GO:0048164 distinct antral spaces stage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048164 mammalian oogenesis stage 7 The stage in oogenesis when the antral spaces become distinct and the first polar body forms. GO:0000105 histidine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000105 MetaCyc:HISTSYN-PWY histidine anabolism|histidine synthesis|histidine formation|histidine biosynthesis The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid. GO:0048163 scattered antral spaces stage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048163 mammalian oogenesis stage 6 The stage in oogenesis when antral spaces begin to form in the follicle cells. Mitochondria form centers for yolk concentration. GO:0000104 succinate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000104 MetaCyc:SUCC-FUM-OXRED-RXN|RHEA:16357 fumarate dehydrogenase activity|succinate:acceptor oxidoreductase activity|succinic dehydrogenase activity|fumarate reductase activity|fumaric hydrogenase activity|succinate oxidoreductase activity|succinodehydrogenase activity|succinyl dehydrogenase activity|succinate:(acceptor) oxidoreductase activity|succinic acid dehydrogenase activity Catalysis of the reaction: succinate + acceptor = fumarate + reduced acceptor. GO:0048162 multi-layer follicle stage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048162 mammalian oogenesis stage 5 The stage in oogenesis when many layers of follicle cells surround the oocyte. There is a yolk nucleus (Balbiani's Body) near the germinal vesicle. GO:0000103 sulfate assimilation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000103 sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor|sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor|sulphate assimilation The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds. GO:0048161 double layer follicle stage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048161 mammalian oogenesis stage 4 The stage in oogenesis when a double layer of distinct follicle cells surrounds the oocyte. An example of this process is found in Mus musculus. GO:0048160 primary follicle stage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048160 mammalian oogenesis stage 3 The stage in oogenesis when a single layer of cuboidal follicle cells surrounds the oocyte. The oocyte nucleus is large. GO:0000102 L-methionine secondary active transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000102 L-methionine porter activity Enables the transfer of L-methionine from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. GO:1903569 positive regulation of protein localization to ciliary membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903569 positive regulation of protein localization in ciliary membrane|upregulation of protein localization to ciliary membrane|up regulation of protein localization in ciliary membrane|activation of protein localisation to ciliary membrane|up-regulation of protein localisation to ciliary membrane|upregulation of protein localisation in ciliary membrane|up-regulation of protein localization to ciliary membrane|activation of protein localization to ciliary membrane|upregulation of protein localization in ciliary membrane|up-regulation of protein localisation in ciliary membrane|activation of protein localisation in ciliary membrane|positive regulation of protein localisation to ciliary membrane|up regulation of protein localisation to ciliary membrane|up-regulation of protein localization in ciliary membrane|activation of protein localization in ciliary membrane|up regulation of protein localization to ciliary membrane|positive regulation of protein localisation in ciliary membrane|up regulation of protein localisation in ciliary membrane|upregulation of protein localisation to ciliary membrane Any process that activates or increases the frequency, rate or extent of protein localization to ciliary membrane. GO:1903568 negative regulation of protein localization to ciliary membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903568 inhibition of protein localization to ciliary membrane|down regulation of protein localisation in ciliary membrane|inhibition of protein localisation in ciliary membrane|downregulation of protein localization in ciliary membrane|down regulation of protein localization in ciliary membrane|negative regulation of protein localisation to ciliary membrane|inhibition of protein localization in ciliary membrane|down-regulation of protein localisation to ciliary membrane|down-regulation of protein localization to ciliary membrane|downregulation of protein localisation to ciliary membrane|down-regulation of protein localisation in ciliary membrane|negative regulation of protein localisation in ciliary membrane|down regulation of protein localisation to ciliary membrane|inhibition of protein localisation to ciliary membrane|downregulation of protein localization to ciliary membrane|down-regulation of protein localization in ciliary membrane|negative regulation of protein localization in ciliary membrane|downregulation of protein localisation in ciliary membrane|down regulation of protein localization to ciliary membrane Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to ciliary membrane. GO:0014748 negative regulation of tonic skeletal muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014748 Any process that stops, prevents, or reduces the frequency, rate or extent of tonic skeletal muscle contraction. GO:1903567 regulation of protein localization to ciliary membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903567 regulation of protein localisation in ciliary membrane|regulation of protein localization in ciliary membrane|regulation of protein localisation to ciliary membrane Any process that modulates the frequency, rate or extent of protein localization to ciliary membrane. GO:0014747 positive regulation of tonic skeletal muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014747 Any process that activates or increases the frequency, rate or extent of tonic skeletal muscle contraction. GO:1903566 positive regulation of protein localization to cilium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903566 up regulation of protein localization to cilium|upregulation of protein localization to cilium|up-regulation of protein localization to cilium|activation of protein localization to cilium Any process that activates or increases the frequency, rate or extent of protein localization to cilium. GO:1903565 negative regulation of protein localization to cilium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903565 down-regulation of protein localization to cilium|downregulation of protein localization to cilium|down regulation of protein localization to cilium|inhibition of protein localization to cilium Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cilium. GO:0048169 regulation of long-term neuronal synaptic plasticity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048169 A process that modulates long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers. GO:1903564 regulation of protein localization to cilium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903564 Any process that modulates the frequency, rate or extent of protein localization to cilium. GO:1903563 microtubule bundle formation involved in horsetail-astral microtubule organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903563 microtubule bundling involved in horsetail-astral microtubule organization|microtubule bundle formation involved in horsetail-astral microtubule array organization|microtubule bundle formation involved in horsetail-astral microtubule organisation|microtubule bundling involved in horsetail-astral microtubule organisation|microtubule bundling involved in horsetail-astral microtubule array organization Any microtubule bundle formation that is involved in horsetail-astral microtubule organization. GO:0048168 regulation of neuronal synaptic plasticity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048168 A process that modulates neuronal synaptic plasticity, the ability of neuronal synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers. GO:1903573 negative regulation of response to endoplasmic reticulum stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903573 down-regulation of response to ER stress|negative regulation of cellular response to endoplasmic reticulum stress|down-regulation of cellular response to endoplasmic reticulum stress|negative regulation of response to ER stress|downregulation of response to endoplasmic reticulum stress|inhibition of response to ER stress|down regulation of response to endoplasmic reticulum stress|inhibition of cellular response to endoplasmic reticulum stress|inhibition of response to endoplasmic reticulum stress|down-regulation of ER stress response|negative regulation of ER stress response|down regulation of response to ER stress|down regulation of cellular response to endoplasmic reticulum stress|downregulation of ER stress response|downregulation of response to ER stress|downregulation of cellular response to endoplasmic reticulum stress|down regulation of ER stress response|down-regulation of response to endoplasmic reticulum stress|inhibition of ER stress response Any process that stops, prevents or reduces the frequency, rate or extent of a response to endoplasmic reticulum stress. GO:0014742 positive regulation of muscle hypertrophy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014742 Any process that activates or increases the frequency, rate or extent of muscle hypertrophy. GO:1903572 positive regulation of protein kinase D signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903572 positive regulation of PKD signal transduction|up regulation of protein kinase D signaling cascade|upregulation of PKD signaling cascade|up-regulation of protein kinase D signalling cascade|activation of protein kinase D signaling|up-regulation of protein kinase D signaling|activation of protein kinase D signal transduction|up-regulation of protein kinase D signal transduction|upregulation of protein kinase D signalling cascade|upregulation of protein kinase D signaling cascade|up-regulation of PKD signal transduction|up regulation of PKD signaling cascade|positive regulation of PKD signaling cascade|up regulation of protein kinase D signaling|positive regulation of protein kinase D signal transduction|activation of PKD signaling cascade|up regulation of protein kinase D signal transduction|up-regulation of protein kinase D signaling cascade|upregulation of PKD signal transduction|up regulation of protein kinase D signalling cascade|positive regulation of protein kinase D signalling cascade|up-regulation of PKD signaling cascade|activation of protein kinase D signaling cascade|upregulation of protein kinase D signaling|activation of protein kinase D signalling cascade|upregulation of protein kinase D signal transduction|positive regulation of protein kinase D signaling cascade|up regulation of PKD signal transduction|activation of PKD signal transduction Any process that activates or increases the frequency, rate or extent of protein kinase D signaling. GO:0014741 negative regulation of muscle hypertrophy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014741 Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hypertrophy. GO:1903571 negative regulation of protein kinase D signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903571 downregulation of protein kinase D signaling cascade|down regulation of PKD signaling cascade|negative regulation of PKD signal transduction|down-regulation of PKD signal transduction|inhibition of protein kinase D signalling cascade|down regulation of protein kinase D signaling cascade|downregulation of PKD signaling cascade|down-regulation of protein kinase D signaling|inhibition of PKD signal transduction|negative regulation of protein kinase D signal transduction|down regulation of protein kinase D signalling cascade|down-regulation of protein kinase D signal transduction|inhibition of protein kinase D signaling cascade|down-regulation of PKD signaling cascade|negative regulation of PKD signaling cascade|downregulation of protein kinase D signalling cascade|downregulation of protein kinase D signaling|downregulation of protein kinase D signal transduction|down regulation of protein kinase D signaling|down regulation of PKD signal transduction|inhibition of protein kinase D signaling|negative regulation of protein kinase D signalling cascade|down regulation of protein kinase D signal transduction|down-regulation of protein kinase D signalling cascade|negative regulation of protein kinase D signaling cascade|down-regulation of protein kinase D signaling cascade|downregulation of PKD signal transduction|inhibition of protein kinase D signal transduction|inhibition of PKD signaling cascade Any process that stops, prevents or reduces the frequency, rate or extent of protein kinase D signaling. GO:0014740 negative regulation of muscle hyperplasia biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014740 Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hyperplasia. GO:1903570 regulation of protein kinase D signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903570 regulation of protein kinase D signaling cascade|regulation of PKD signaling cascade|regulation of protein kinase D signalling cascade|regulation of protein kinase D signal transduction|regulation of PKD signal transduction Any process that modulates the frequency, rate or extent of protein kinase D signaling. GO:0014746 regulation of tonic skeletal muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014746 Any process that modulates the frequency, rate or extent of tonic skeletal muscle contraction. GO:0014745 negative regulation of muscle adaptation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014745 negative regulation of muscle plasticity Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle adaptation. GO:0014744 positive regulation of muscle adaptation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014744 positive regulation of muscle plasticity Any process that activates or increases the frequency, rate or extent of muscle adaptation. GO:0014743 regulation of muscle hypertrophy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014743 Any process that modulates the frequency, rate or extent of muscle hypertrophy. GO:0048170 positive regulation of long-term neuronal synaptic plasticity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048170 up regulation of long-term neuronal synaptic plasticity|upregulation of long-term neuronal synaptic plasticity|stimulation of long-term neuronal synaptic plasticity|up-regulation of long-term neuronal synaptic plasticity|activation of long-term neuronal synaptic plasticity A process that increases long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers. GO:0000109 nucleotide-excision repair complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0000109 UvrB-UvrC complex|UvrBC complex Any complex formed of proteins that act in nucleotide-excision repair. CHEBI:38264 2-amino-3-methylpentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38264 GO:0000108 obsolete repairosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000108 repairosome OBSOLETE. A stable complex of proteins that carry out the DNA damage recognition and incision reactions characteristic of nucleotide excision repair (NER), such as DNA damage recognition, DNA helix unwinding, and endonucleolytic cleavage at sites flanking damaged DNA; includes TFIIH subunits and additional polypeptides; may form in the absence of DNA damage. CHEBI:38263 2-amino-3-hydroxybutanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38263 CHEBI:38262 allothreonine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38262 GO:0000107 imidazoleglycerol-phosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000107 MetaCyc:GLUTAMIDOTRANS-RXN|RHEA:24795 imidazole-glycerol-phosphate synthase activity|glutamine amidotransferase:cyclase activity|imidazoleglycerol phosphate synthase activity|imidazole glycerol phosphate synthase activity Catalysis of the reaction: phosphoribulosylformimino-AICAR-P + L-glutamine = D-erythro-imidazole-glycerol-phosphate + aminoimidazole carboxamide ribonucleotide + L-glutamate + 2 H(+). CHEBI:38261 imidazolidines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38261 GO:0000106 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000106 CHEBI:38266 O-beta-D-glucosyl-trans-zeatin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38266 CHEBI:38265 carvone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38265 GO:0000112 nucleotide-excision repair factor 3 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000112 NEF3 complex One of several protein complexes involved in nucleotide-excision repair; possesses endodeoxynuclease and DNA helicase activities. In S. cerevisiae, it is composed of Rad2p and the core TFIIH-Ssl2p complex (core TFIIH is composed of Rad3p, Tfb1p, Tfb2p, Ssl1p, Tfb4p and Tfb5p. Note that Ssl2p is also called Rad25p). GO:0048178 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048178 GO:0000111 nucleotide-excision repair factor 2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000111 NEF2 complex One of several protein complexes involved in nucleotide-excision repair; possesses damaged DNA binding activity. In S. cerevisiae, it is composed of Rad4p and Rad23p. GO:0048177 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048177 GO:0000110 nucleotide-excision repair factor 1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000110 XPA-ERCC1-ERCC4 complex|NEF1 complex One of several protein complexes involved in nucleotide-excision repair; possesses DNA damage recognition and endodeoxynuclease activities. In S. cerevisiae, it is composed of Rad1p, Rad10p, and Rad14p; in human the subunits are ERCC4/XPF, ERCC1 and XPA, respectively. GO:0048176 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048176 GO:0048175 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048175 GO:0048174 negative regulation of short-term neuronal synaptic plasticity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048174 inhibition of short-term neuronal synaptic plasticity|down regulation of short-term neuronal synaptic plasticity|downregulation of short-term neuronal synaptic plasticity|down-regulation of short-term neuronal synaptic plasticity A process that decreases short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity. GO:0000116 obsolete regulation of transcription involved in G2-phase of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000116 regulation of transcription from RNA polymerase II during G2-phase of mitotic cell cycle|regulation of transcription involved in G2-phase of mitotic cell cycle|G2-specific transcription in mitotic cell cycle OBSOLETE. Any process that regulates transcription such that the target genes are transcribed as part of the G2 phase of the mitotic cell cycle. GO:0000115 obsolete regulation of transcription involved in S phase of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000115 S-specific transcription in mitotic cell cycle|regulation of transcription involved in S phase of mitotic cell cycle|regulation of transcription involved in S-phase of mitotic cell cycle|S-phase-specific transcription in mitotic cell cycle|regulation of transcription from RNA polymerase II promoter during S-phase of mitotic cell cycle OBSOLETE. A cell cycle process that regulates transcription such that the target genes are transcribed as part of the S phase of the mitotic cell cycle. GO:0048173 positive regulation of short-term neuronal synaptic plasticity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048173 up-regulation of short-term neuronal synaptic plasticity|upregulation of short-term neuronal synaptic plasticity|up regulation of short-term neuronal synaptic plasticity|activation of short-term neuronal synaptic plasticity|stimulation of short-term neuronal synaptic plasticity A process that increases short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity. GO:0000114 obsolete regulation of transcription involved in G1 phase of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000114 regulation of transcription involved in G1 phase of mitotic cell cycle|regulation of transcription from RNA polymerase II promoter during G1 phase of cell cycle|G1-specific transcription in mitotic cell cycle OBSOLETE. Any process that regulates transcription such that the target genes are transcribed as part of the G1 phase of the mitotic cell cycle. GO:0048172 regulation of short-term neuronal synaptic plasticity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048172 A process that modulates short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity. GO:0048171 negative regulation of long-term neuronal synaptic plasticity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048171 downregulation of long-term neuronal synaptic plasticity|down regulation of long-term neuronal synaptic plasticity|inhibition of long-term neuronal synaptic plasticity|down-regulation of long-term neuronal synaptic plasticity A process that decreases long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers. GO:0000113 nucleotide-excision repair factor 4 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000113 NEF4 complex One of several protein complexes involved in nucleotide-excision repair; possesses DNA damage recognition and DNA-dependent ATPase activities. In S. cerevisiae, it is composed of Rad7p and Rad16p. CHEBI:133406 N-acetyl-L-methionyl-L-lysyl(1+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133406 CHEBI:133405 L-methionyl-L-threonyl(1+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133405 CHEBI:133408 13,14-dihydro-15-oxoprostaglandin E1(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133408 GO:1903579 negative regulation of ATP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903579 down-regulation of ATP metabolic process|downregulation of ATP metabolism|down regulation of ATP metabolism|inhibition of ATP metabolism|inhibition of ATP metabolic process|down regulation of ATP metabolic process|downregulation of ATP metabolic process|down-regulation of ATP metabolism|negative regulation of ATP metabolism Any process that stops, prevents or reduces the frequency, rate or extent of ATP metabolic process. CHEBI:133407 L-methionyl-L-lysyl(2+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133407 GO:1903578 regulation of ATP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903578 regulation of ATP metabolism Any process that modulates the frequency, rate or extent of ATP metabolic process. GO:1903577 cellular response to L-arginine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903577 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-arginine stimulus. GO:1903576 response to L-arginine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903576 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-arginine stimulus. CHEBI:133409 15-oxoprostaglandin F2alpha(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133409 GO:1903575 cornified envelope assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903575 cornified envelope formation The aggregation, arrangement and bonding together of a set of components to form a cornified envelope. GO:1903574 negative regulation of cellular response to amino acid starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903574 inhibition of cellular response to amino acid starvation|down-regulation of cellular response to amino acid starvation|downregulation of cellular response to amino acid starvation|down regulation of cellular response to amino acid starvation Any process that stops, prevents or reduces the frequency, rate or extent of a cellular response to amino acid starvation. GO:0048179 activin receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0048179 A protein complex that acts as an activin receptor. Heterodimeric activin receptors, comprising one Type I activin receptor and one Type II receptor polypeptide, and heterotrimeric receptors have been observed. GO:1903584 regulation of histone deubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903584 regulation of histone deubiquitylation|regulation of histone deubiquitinylation Any process that modulates the frequency, rate or extent of histone deubiquitination. GO:1903583 positive regulation of basophil degranulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903583 up regulation of basophil degranulation|upregulation of basophil degranulation|up-regulation of basophil degranulation|activation of basophil degranulation Any process that activates or increases the frequency, rate or extent of basophil degranulation. GO:1903582 negative regulation of basophil degranulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903582 downregulation of basophil degranulation|down regulation of basophil degranulation|inhibition of basophil degranulation|down-regulation of basophil degranulation Any process that stops, prevents or reduces the frequency, rate or extent of basophil degranulation. CHEBI:133400 N-acetyl-L-methionyl-L-seryl residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133400 GO:1903581 regulation of basophil degranulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903581 Any process that modulates the frequency, rate or extent of basophil degranulation. GO:1903580 positive regulation of ATP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903580 upregulation of ATP metabolic process|up-regulation of ATP metabolism|activation of ATP metabolism|up regulation of ATP metabolic process|positive regulation of ATP metabolism|activation of ATP metabolic process|up regulation of ATP metabolism|up-regulation of ATP metabolic process|upregulation of ATP metabolism Any process that activates or increases the frequency, rate or extent of ATP metabolic process. CHEBI:133402 N-acetyl-L-methionyl-L-valyl residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133402 CHEBI:133401 L-methionyl-L-seryl(1+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133401 CHEBI:133404 N-acetyl-L-methionyl-L-threonyl residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133404 CHEBI:133403 L-methionyl-L-valyl(1+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133403 GO:0048181 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048181 CHEBI:38275 pyrrolidinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38275 GO:0000119 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000119 GO:0048180 activin complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0048180 A nonsteroidal regulator, composed of two covalently linked inhibin beta subunits, inhibin beta-A and inhibin beta-B (sometimes known as activin beta or activin/inhibin beta). There are three forms of activin complex, activin A, which is composed of 2 inhibin beta-A subunits, activin B, which is composed of 2 inhibin beta-B subunits, and activin AB, which is composed of an inhibin beta-A and an inhibin beta-B subunit. GO:0000118 histone deacetylase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000118 HDAC complex A protein complex that possesses histone deacetylase activity. GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000117 regulation of transcription from RNA polymerase II promoter during G2/M transition of mitotic cell cycle|G2/M-specific transcription in mitotic cell cycle Any process that regulates transcription such that the target genes are transcribed as part of the G2/M transition of the mitotic cell cycle. NCBITaxon:Union_0000002 Viridiplantae or Cyanobacteria organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_Union_0000002 The union of the taxa Viridiplantae and Cyanobacteria. CHEBI:77858 4-hydroxycoumarin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77858 CHEBI:77857 cyanidin 3-O-beta-D-glucoside(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77857 NCBITaxon:Union_0000004 Prokaryota organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_Union_0000004 NCBITaxon:Union_0000003 Myxininae or Petromyzontidae organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_Union_0000003 NCBITaxon:Union_0000006 Viridiplantae or Archaea or Bacteria organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_Union_0000006 NCBITaxon:Union_0000005 obsolete Nematoda or Protostomia organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_Union_0000005 Invertebrata NCBITaxon:Union_0000008 Viridiplantae or Euglenozoa organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_Union_0000008 CHEBI:77859 2-ammoniomuconate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77859 NCBITaxon:Union_0000007 Viridiplantae or Bacteria or Euglenozoa organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_Union_0000007 CHEBI:63212 2-hydroxy-dAMP(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63212 CHEBI:63211 2-hydroxy-dAMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63211 CHEBI:63217 5(S),8(R)-DiHODE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63217 CHEBI:63216 5(S),8(R)-DiHODE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63216 PR:000001423 histamine H2 receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001423 HH2R|H2 histamine receptor|gastric receptor I|HRH2|H2R A histamine receptor that is a translation product of the human HRH2 gene or a 1:1 ortholog thereof. The preferred ligand is histamine. This receptor mediates smooth muscle relaxation, gastric acid secretion, and other diverse effects. PR:000001422 histamine H1 receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001422 H1 histamine receptor|HH1R|Bphs|HRH1|H1R A histamine receptor that is a translation product of the human HRH1 gene or a 1:1 ortholog thereof. PR:000001426 KiSS-1 receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001426 GPR54|KISS1R|hypogonadotropin-1|AXOR12|metastin receptor|KiSS-1R|OT7T175|G-protein coupled receptor OT7T175|kisspeptins receptor|G-protein coupled receptor 54 A rhodopsin-like G-protein coupled receptor that is a translation product of the human KISS1R gene or a 1:1 ortholog thereof. The preferred ligands are peptides of 10-54 residues derived from the metastasis-suppressor KiSS-1 protein. CHEBI:77853 persistent organic pollutant biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77853 CHEBI:77852 9(S)-HODE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77852 CHEBI:77851 (2S)-2-ammonio-3-oxo-4-(phosphonatooxy)butanoate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77851 CHEBI:77869 (E,E)-sorbate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77869 CHEBI:63220 8-oxo-dGTP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63220 CHEBI:63224 8-oxo-dGMP(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63224 CHEBI:63223 8-oxo-dGMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63223 CHEBI:63222 8-oxo-dGTP(3-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63222 PR:000001431 N-formyl peptide receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001431 formylpeptide receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human FPR1, FPR2, or FPR3 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds N-formyl methionyl peptides. CHEBI:77860 3-cyano-L-alanine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77860 PR:000001439 adenosine receptor protein biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001439 A rhodopsin-like G-protein coupled receptor that is a translation product of the human ADORA1, ADORA2A, ADORA2B, or ADORA3 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds adenosine. NCBITaxon:Union_0000000 Viridiplantae or Bacteria organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_Union_0000000 CHEBI:77862 gossypetin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77862 NCBITaxon:Union_0000024 Unikonta organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_Union_0000024 unikonts The unikonts have a triple-gene fusion that is lacking in the bikonts. The three genes that are fused together in the unikonts but not bacteria or bikonts encode enzymes for synthesis of the pyrimidine nucleotides: carbamoyl phosphate synthase, dihydroorotase, aspartate carbamoyltransferase. This must have involved a double fusion, a rare pair of events, supporting the shared ancestry of Opisthokonta and Amoebozoa. NCBITaxon:Union_0000023 Fungi or Bacteria or Archaea organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_Union_0000023 CHEBI:77877 3,3'-biflaviolin(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77877 NCBITaxon:Union_0000025 Archaea or Eukaryota organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_Union_0000025 archaea-eukaryota CHEBI:87200 dicarboximide antifungal agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87200 CHEBI:63239 (10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63239 CHEBI:63238 (10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63238 CHEBI:63237 (9R,10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63237 CHEBI:77872 precorrin-6A(7-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77872 CHEBI:77871 precorrin-5(7-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77871 CHEBI:77870 precorrin-3B(6-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77870 CHEBI:77876 biochanin A 7-O-beta-D-glucoside 6''-O-malonate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77876 NCBITaxon:Union_0000031 Stramenopiles or Cryptophyta organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_Union_0000031 CHEBI:77875 iminoaspartate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77875 NCBITaxon:Union_0000030 cellular organisms or viruses organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_Union_0000030 CHEBI:77874 hydrogenobyrinic acid a,c-diamide(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77874 CHEBI:77873 hydrogenobyrinate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77873 CHEBI:77889 N-[omega-(9R)-hydroperoxy(10E,12Z)-octadecadienoyloxy]acylsphin-4-enine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77889 CHEBI:77888 N-[omega-(linoleoyloxy)]acylsphin-4-enine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77888 CHEBI:63241 (9R,10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63241 CHEBI:63245 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63245 CHEBI:63244 pentalen-13-al biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63244 CHEBI:63243 pentalen-13-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63243 CHEBI:63249 (Z)-2-methylureidoperacrylic acid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63249 CHEBI:63248 oxidising agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63248 CHEBI:63247 reducing agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63247 CHEBI:77881 EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77881 NCBITaxon:Union_0000020 Fungi or Bacteria organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_Union_0000020 CHEBI:77887 delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77887 CHEBI:77886 demethylsulochrin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77886 CHEBI:77885 nocardicin E(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77885 NCBITaxon:Union_0000022 Fungi or Dictyostelium organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_Union_0000022 NCBITaxon:Union_0000021 Viridiplantae or Bacteria or Euglenozoa or Archaea organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_Union_0000021 CHEBI:77899 (S)-averantin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77899 CHEBI:63253 3-oxo-5,6-dehydrosuberyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63253 CHEBI:63252 2-oxepin-2(3H)-ylideneacetyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63252 CHEBI:63251 2-oxepin-2(3H)-ylideneacetyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63251 PR:000025433 nodal protein proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000025433 NODAL/ClvPrd A nodal protein that has been processed by proteolytic cleavage. CHEBI:63250 (Z)-2-methyl-3-aminoperacrylic acid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63250 CHEBI:63257 3,8-dioxooct-5-enoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63257 CHEBI:63256 3,8-dioxooct-5-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63256 CHEBI:63255 3-oxo-5,6-dehydrosuberyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63255 CHEBI:133497 3-(2-methylthioethyl)malate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133497 CHEBI:87228 sulfonamide antibiotic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87228 CHEBI:133496 3-(omega-methylthio)alkylmalate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133496 PR:000001463 glycoprotein hormone receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001463 A rhodopsin-like G-protein coupled receptor that is a translation product of the human FSHR, LHCGR, or TSHR genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds glycoprotein hormones (thyrotropin, follitropin, lutropin, choriogonadotropin). CHEBI:133499 2-(2-methylthio)ethylmaleate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133499 CHEBI:133498 2-(omega-methylthio)alkylmaleate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133498 CHEBI:77890 1-O-palmitoyl-2-O-(5-oxovaleryl)-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77890 PR:000001464 gonadotropin-releasing hormone receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001464 A rhodopsin-like G-protein coupled receptor that is a translation product of the human GNRHR or GNRHR2 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds gonadotropin-releasing hormone I or II. CHEBI:77894 aci-nitroethane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77894 PR:000001468 intercellular adhesion molecule 3 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001468 CD50|CDw50|ICAM3|ICAM-3|ICAM-R An intercellular adhesion molecule 1/3 that is a translation product of the human ICAM3 gene or a 1:1 ortholog thereof. CHEBI:77893 3-(4-oxo-4,5-dihydro-1H-imidazol-5-yl)propanoate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77893 CHEBI:133491 alpha-D-Gal-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133491 CHEBI:133490 saturated fatty acyl-AMP(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133490 CHEBI:77891 N-[omega-(9R,10R)-epoxy-(13R)-hydroxy-(11E)-octadecenoyloxy]sphing-4-enine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77891 CHEBI:133493 omega-(methylthio)-2-oxocarboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133493 CHEBI:133492 polyunsaturated dicarboxylic acid dianion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133492 CHEBI:77897 2-hydroxy-dATP(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77897 CHEBI:77896 8-oxo-dGTP(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77896 CHEBI:77895 9(R)-HODE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77895 CHEBI:133494 2-(omega-methylthio)alkylmalate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133494 UBERON:0035371 retroperitoneal lymph node biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035371 retroperitoneal node A lymph node located in the retroperitoneal space. CHEBI:63260 dTDP-alpha-D-desosamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63260 CHEBI:63264 dTDP-3-amino-3,6-dideoxy-alpha-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63264 CHEBI:63263 beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GalpNAc(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63263 CHEBI:63262 dTDP-3-azaniumyl-3,4,6-trideoxy-alpha-D-glucose(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63262 CHEBI:63268 dTDP-alpha-D-mycaminose(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63268 CHEBI:63267 beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GalpNAc6S(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63267 CHEBI:63266 4-deoxy-Delta(4)-beta-D-GlcpA-(1->3)-beta-D-GalpNAc6S biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63266 CHEBI:87215 N-terminal 5-oxo-L-proline residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87215 CHEBI:63265 dTDP-3-azaniumyl-3,6-dideoxy-alpha-D-glucose(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63265 PR:000001472 interleukin-19 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001472 NG.1|ZMDA1|melanoma differentiation-associated protein-like protein|IL-19|IL19 A class 2 cytokine, IL-10 type that is a translation product of the human IL19 gene or a 1:1 ortholog thereof. PR:000001471 interleukin-10 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001471 IL10|cytokine synthesis inhibitory factor|CSIF|IL-10 A class 2 cytokine, IL-10 type that is a translation product of the human IL10 gene or a 1:1 ortholog thereof. Active interleukin-10 inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T cells. Structurally, IL-10 is a protein of about 160 amino acids that contains four conserved cysteines involved in disulfide bonds. PR:000001474 interleukin-24 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001474 MDA7|IL24|melanoma differentiation-associated gene 7 protein|ST16|Th2-specific cytokine FISP|MDA-7|suppression of tumorigenicity 16 protein|IL-24|IL-4-induced secreted protein A class 2 cytokine, IL-10 type that is a translation product of the human IL24 gene or a 1:1 ortholog thereof. PR:000001473 interleukin-20 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001473 IL-20|ZCYTO10|IL20|cytokine Zcyto10 A class 2 cytokine, IL-10 type that is a translation product of the human IL20 gene or a 1:1 ortholog thereof. CHEBI:63269 dTDP-3-dehydro-6-deoxy-alpha-D-glucose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63269 PR:000001475 interleukin-26 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001475 IL26|AK155|IL-26|protein AK155 A class 2 cytokine, IL-10 type that is a translation product of the human IL26 gene or a 1:1 ortholog thereof. GO:0000189 obsolete MAPK import into nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000189 nuclear translocation of MAPK OBSOLETE. The directed movement of a MAP kinase to the nucleus upon activation. GO:0000188 inactivation of MAPK activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000188 termination of MAPK activity|inactivation of MAPK during sporulation Any process that terminates the activity of the active enzyme MAP kinase. GO:0000187 activation of MAPK activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000187 MAPK activation|activation of MAP kinase|activation of MAPK activity during sporulation The initiation of the activity of the inactive enzyme MAP kinase (MAPK). GO:0000186 activation of MAPKK activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000186 activation of MAP/ERK kinase kinase|activation of MAP2K activity|positive regulation of MAPKK activity|activation of MAPKK activity during sporulation|activation of MAP kinase kinase activity The initiation of the activity of the inactive enzyme MAP kinase kinase (MAPKK). CHEBI:63271 4-deoxy-Delta(4)-beta-D-GlcpA2S-(1->3)-beta-D-GalpNAc biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63271 CHEBI:63270 N-acetyl-beta-D-galactosamine 6-sulfate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63270 UBERON:0035383 lateral wall of nasopharynx biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035383 lateral nasopharynx GO:0000181 obsolete cytosolic small ribosomal subunit biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000181 cytosolic small ribosomal subunit OBSOLETE. (Was not defined before being made obsolete). CHEBI:87242 palmitoyllipid A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87242 CHEBI:63275 5-dehydro-4-deoxy-2-O-sulfo-D-glucuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63275 GO:0000180 obsolete cytosolic large ribosomal subunit biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000180 cytosolic large ribosomal subunit OBSOLETE. (Was not defined before being made obsolete). CHEBI:63274 4-deoxy-Delta(4)-beta-D-GlcpA2S-(1->3)-beta-D-GalpNAc(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63274 CHEBI:63273 UDP-2-acetamido-4-amino-2,4,6-trideoxy-alpha-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63273 CHEBI:87244 lipid IVB biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87244 GO:0000185 activation of MAPKKK activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000185 activation of MAP3K activity|activation of MAP kinase kinase kinase|activation of MAPKKK activity during sporulation|positive regulation of MAP kinase kinase kinase activity|positive regulation of MAPKKK activity Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase (MAPKKK). GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000184 Wikipedia:Nonsense-mediated_mRNA_decay|Wikipedia:Nonsense-mediated_decay mRNA breakdown, nonsense-mediated decay|mRNA degradation, nonsense-mediated decay|nonsense-mediated mRNA decay|mRNA catabolic process, nonsense-mediated|nuclear mRNA catabolic process, nonsense-mediated decay|mRNA catabolism, nonsense-mediated The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins. CHEBI:87245 lipid IIB biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87245 CHEBI:63278 5-dehydro-4-deoxy-2-O-sulfo-D-glucuronic acid(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63278 GO:0000183 rDNA heterochromatin assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000183 rDNA chromatin silencing|chromatin silencing at ribosomal DNA|heterochromatic silencing at rDNA|chromatin silencing at rDNA The assembly of chromatin characterized by the modified histone H3K9me3, into heterochromatin, resulting in the repression of transcription of rDNA. CHEBI:63277 UDP-2-acetamido-4-azaniumyl-2,4,6-trideoxy-alpha-D-glucose(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63277 GO:0000182 rDNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000182 ribosomal DNA binding Interacting selectively and non-covalently with DNA sequences encoding ribosomal RNA. CHEBI:63276 mycinamicin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63276 CHEBI:133476 hydantoin-5-propionate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133476 CHEBI:133479 S-(long-chain fatty acyl)-L-cysteine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133479 PR:000001442 blood group Rh(D) polypeptide biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001442 RhPII|CD240D|rhesus D antigen|RHD|Rh polypeptide 2|blood group RhD polypeptide|RHXIII An erythrocyte membrane protein Rh that is a translation product of the human RHD gene or a 1:1 ortholog thereof. PR:000001449 fibroblast growth factor receptor 2 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001449 K-sam|Ect1|FGFR-2|CD332|KSAM|keratinocyte growth factor receptor|FGFR2|BEK|KGFR A fibroblast growth factor receptor that is a translation product of the human FGFR2 gene or a 1:1 ortholog thereof. CHEBI:133470 beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133470 CHEBI:495505 dATP(3-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_495505 GO:0000199 activation of MAPK activity involved in cell wall organization or biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000199 cell wall biogenesis, activation of MAPK activity|activation of MAPK activity involved in cell wall integrity|activation of MAPK activity involved in cell wall biogenesis Any process that initiates the activity of the inactive enzyme MAP kinase in the context of cell wall biogenesis, the assembly and arrangement of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells. GO:0000198 activation of MAPKK activity involved in cell wall organization or biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000198 activation of MAPKK activity involved in cell wall integrity|activation of MAP kinase kinase activity during cell wall biogenesis|activation of MAPKK activity involved in cell wall biogenesis|cell wall biogenesis, activation of MAPKK activity|cell wall biogenesis, activation of MAP kinase kinase activity Any process that initiates the activity of the inactive enzyme MAP kinase kinase in the context of cell wall organization or biogenesis. GO:0000197 activation of MAPKKK activity involved in cell wall organization or biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000197 cell wall biogenesis, activation of MAP kinase kinase kinase activity|cell wall biogenesis, activation of MAPKKK activity|activation of MAPKKK activity involved in cell wall biogenesis|activation of MAPKKK activity involved in cell wall integrity|activation of MAP kinase kinase kinase activity during cell wall biogenesis Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase in the context of cell wall organization or biogenesis. CHEBI:63282 pseudaminate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63282 CHEBI:63281 pseudaminic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63281 CHEBI:63280 beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GlcpNAc(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63280 GO:0000192 obsolete activation of MAPKK (pseudohyphal growth) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000192 activation of MAPKK (pseudohyphal growth) OBSOLETE. Upregulation of a MAP kinase kinase in the context of regulating pseudohyphal or invasive growth. CHEBI:63286 dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63286 CHEBI:63285 mycinamicin VI biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63285 GO:0000191 obsolete activation of MAPKKK (pseudohyphal growth) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000191 activation of MAPKKK (pseudohyphal growth) OBSOLETE. Upregulation of MAPKKK activity in the context of regulating pseudohyphal or invasive growth. CHEBI:87230 nitrofuran antibiotic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87230 GO:0000190 obsolete MAPKKK cascade (pseudohyphal growth) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000190 MAPKKK cascade (pseudohyphal growth) OBSOLETE. MAPKKK cascade involved in transduction of signal promoting pseudohyphal or invasive growth. CHEBI:63284 mycinamicin IV biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63284 CHEBI:63283 2,4-diacetamido-2,4,6-trideoxy-beta-L-altrose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63283 UBERON:0035398 branch of external carotid artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035398 subdivision of external carotid artery|external carotid arterial subdivision GO:0000196 cell wall integrity MAPK cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000196 PMK1-MAPK signal transduction pathway|Mpk1 cascade|cell wall biogenesis, MAPKKK cascade|Pmk1 MAPK cell integrity signaling|MAPKKK cascade involved in cell wall biogenesis|MAPK cascade involved in cell wall biogenesis|cell integrity MAPK pathway|MAPK cascade involved in cell wall organization or biogenesis|Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|Slt2 cascade A MAPK cascade that contributes to cell wall organization or biogenesis. GO:0000195 obsolete nuclear translocation of MAPK (pseudohyphal growth) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000195 nuclear translocation of MAPK (pseudohyphal growth) OBSOLETE. Movement of a MAP kinase to the nucleus in the context of regulating pseudohyphal or invasive growth. GO:0000194 obsolete inactivation of MAPK (pseudohyphal growth) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000194 inactivation of MAPK (pseudohyphal growth) OBSOLETE. Downregulation of MAP kinase activity in the context of regulating pseudohyphal or invasive growth. GO:0000193 obsolete activation of MAPK (pseudohyphal growth) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000193 activation of MAPK (pseudohyphal growth) OBSOLETE. Upregulation of MAP kinase activity in the context of regulating pseudohyphal or invasive growth. CHEBI:63287 3-amino-3,6-dideoxy-alpha-D-galactopyranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63287 PR:000001457 galanin receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001457 A rhodopsin-like G-protein coupled receptor that is a translation product of the human GALR1 to GALR3 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds the neuropeptide galanin. CHEBI:28847 D-fucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28847 CHEBI:28846 dCDP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28846 CHEBI:28843 5-amino-1-(5-phospho-D-ribosyl)imidazole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28843 CHEBI:28842 octadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28842 CHEBI:53800 4-hydroxy-2-oxohexanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_53800 CHEBI:28858 1D-myo-inositol 3,4-bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28858 CHEBI:28857 (Z)-hex-3-en-1-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28857 CHEBI:28859 5alpha-androstane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28859 CHEBI:28854 2,4-D biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28854 CHEBI:28853 isopimpinellin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28853 CHEBI:28856 p-toluate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28856 CHEBI:28855 enterobactin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28855 CHEBI:28850 dUDP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28850 CHEBI:28852 prostaglandin F1alpha biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28852 CHEBI:28851 phenanthrene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28851 GO:0097299 obsolete cysteine-type endopeptidase activity involved in plant-type hypersensitive response biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097299 metacaspase activity involved in plant-type hypersensitive response OBSOLETE. Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to plant-type hypersensitive response, the rapid, localized death of plant cells in response to invasion by a pathogen. GO:0097298 regulation of nucleus size biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097298 regulation of nuclear volume|regulation of nuclear size Any process that modulates the size of the nucleus. CHEBI:28824 stigmasterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28824 CHEBI:28827 sparteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28827 CHEBI:28826 fluoromethane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28826 GO:0097295 morphine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097295 morphine biosynthesis|morphine anabolism|morphine synthesis|morphine formation The chemical reactions and pathways resulting in the formation of morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum. CHEBI:28821 piperine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28821 GO:0097294 'de novo' XMP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097294 'de novo' XMP synthesis|'de novo' XMP formation|'de novo' XMP biosynthesis|'de novo' XMP anabolism The chemical reactions and pathways resulting in the formation of XMP, xanthosine monophosphate, from simpler precursors. GO:0097297 activation of cysteine-type endopeptidase activity involved in execution phase of apoptosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097297 activation of effector caspase activity Any process that initiates the activity of an inactive cysteine-type endopeptidase involved in the execution phase of apoptosis. CHEBI:28823 2'-deoxyinosine-5'-diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28823 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signalling pathway|activation of initiator caspase activity Any process that initiates the activity of an inactive cysteine-type endopeptidase involved in the apoptotic signaling pathway. CHEBI:28822 icosanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28822 GO:0097291 renal phosphate ion absorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097291 renal phosphate absorption A renal system process in which phosphate ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures. GO:0097290 alpha-ribazole biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097290 alpha-ribazole formation|alpha-ribazole biosynthesis|alpha-ribazole anabolism|alpha-ribazole synthesis The chemical reactions and pathways resulting in the formation of alpha-ribazole, the benzimidazole nucleoside in adenosyl cobalamin (vitamin B12). GO:0097293 XMP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097293 XMP anabolism|XMP biosynthesis|XMP synthesis|XMP formation The chemical reactions and pathways resulting in the formation of XMP, xanthosine monophosphate. GO:0097292 XMP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097292 XMP metabolism The chemical reactions and pathways involving XMP, xanthosine monophosphate. CHEBI:14216 erythrulose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_14216 CHEBI:28829 aminophenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28829 CHEBI:77803 2-ammonio-3-(3-oxoprop-1-enyl)but-2-enedioate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77803 CHEBI:28835 testosterone 17-glucosiduronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28835 CHEBI:77802 uridine 2'-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77802 CHEBI:28838 lutein biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28838 CHEBI:28837 octanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28837 CHEBI:77800 2'-hydroxydaidzein(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77800 CHEBI:28831 propan-1-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28831 CHEBI:77805 enterobactin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77805 CHEBI:28834 deoxycholic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28834 UBERON:0035471 posterior surface of kidney biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035471 facies posterior renis|facies posterior (Ren) CHEBI:28833 gibberellin A3 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28833 CHEBI:77804 biochanin A 7-O-beta-D-glucoside(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77804 CHEBI:28839 3-disulfanyl-L-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28839 CHEBI:28803 pyridoxine 5'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28803 CHEBI:28802 flavonols biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28802 CHEBI:77812 9-oxononanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77812 CHEBI:28804 D-2-aminopentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28804 CHEBI:77811 1-acyl-2-hexadecenoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77811 CHEBI:28800 N-acetylgalactosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28800 UBERON:0035401 posterior wall of nasopharynx biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035401 posterior nasopharynx UBERON:0035403 hypophysial artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035403 An artery that supplies the pituitary gland. CHEBI:77810 2-16:1-lysophosphatidate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77810 CHEBI:28807 dITP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28807 CHEBI:28806 2'-deoxyinosine-5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28806 CHEBI:28808 mannan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28808 CHEBI:77825 luteolin 7-O-[(beta-D-glucosyluronate)-(1->2)-(beta-D-glucosiduronate)] 4'-O-beta-D-glucosiduronate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77825 CHEBI:28813 sinapyl alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28813 CHEBI:77824 cyanidin 3-O-(2-O-beta-D-glucuronosyl)-beta-D-glucoside(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77824 CHEBI:28815 heparan sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28815 CHEBI:77828 guanosine 3',5'-bis(diphosphate)(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77828 CHEBI:28812 (aminomethyl)phosphonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28812 CHEBI:77827 2-arylethylammomium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77827 CHEBI:77826 mugineate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77826 PR:000001631 nociceptin receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001631 OPRL1|Oprl|KOR-3|OOR|kappa-type 3 opioid receptor|ORL1|ORGC|orphanin FQ receptor|K3 opiate receptor An opioid receptor protein that is a translation product of the human OPRL1 gene or a 1:1 ortholog thereof. The preferred ligand is nociceptin. PR:000001635 oxytocin receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001635 OT-R|OXTR A vasopressin/oxytocin receptor that is a translation product of the human OXTR gene or a 1:1 ortholog thereof. The preferred ligand is oxytocin. CHEBI:28818 (24R)-24,25-dihydroxycalciol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28818 CHEBI:28817 dodecane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28817 CHEBI:77836 N-[omega-(acylyloxy)]acylsphin-4-enine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77836 CHEBI:77833 1-palmitoyl-2-valeroyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77833 CHEBI:77838 delphinidin 3-O-beta-D-glucoside-5-O-beta-D-glucoside betaine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77838 CHEBI:77832 1-palmitoyl-2-butanoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77832 CHEBI:77831 1-palmitoyl-2-propionyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77831 CHEBI:77830 2-arachidonoyl-sn-glycero-3-phospho-L-serine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77830 CHEBI:77847 glycerol 1-phosphodiester(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77847 CHEBI:77846 dehydroglycine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77846 CHEBI:77844 delphinidin 3,3',5-tri-O-beta-D-glucoside betaine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77844 CHEBI:77848 3-(3,4-dihydroxypyridinium-1-yl)-L-alanine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77848 UBERON:0035431 mediastinal pleura biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035431 pars mediastinalis (pleurae)|mediastinal part of parietal pleura|pars mediastinalis pleurae parietalis The parietal pleura that lines the mediastinum. CHEBI:63202 dTDP-D-ravidosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63202 UBERON:0035435 right suprarenal vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035435 vena suprarenalis (adrenalis) dextra A vein that drains blood from the right adrenal gland into the inferior vena cava. CHEBI:63205 (+)-gamma-cadinene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63205 CHEBI:63203 (-)-gamma-cadinene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63203 CHEBI:63209 2-hydroxy-dATP(3-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63209 CHEBI:63208 2-hydroxy-dATP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63208 CHEBI:63207 mycinamicin III biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63207 PR:000001612 mu-type opioid receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001612 MOR1|mu opiate receptor|Oprm|OPRM1|mu-opioid receptor|MOR-1|MOP|Mor|M-OR-1|mu opioid receptor An opioid receptor protein that is a translation product of the human OPRM1 gene or a 1:1 ortholog thereof. The preferred ligands are beta-endorphin and enkephalins. CHEBI:77843 thymidine 3'-monophosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77843 CHEBI:77842 stipitatate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77842 CHEBI:77840 3,8'-biflaviolin 2,7,2'-triolate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77840 GO:0097233 alveolar lamellar body membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097233 The lipid bilayer surrounding an alveolar lamellar body, a specialized secretory organelle found in type II pneumocytes and involved in the synthesis, secretion, and reutilization of pulmonary surfactant. GO:0000321 re-entry into mitotic cell cycle after pheromone arrest biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000321 The resumption of the mitotic cell division cycle by pheromone-arrested cells that have not mated. An example of this process is found in Saccharomyces cerevisiae. GO:0097232 lamellar body membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097232 The lipid bilayer surrounding a lamellar body. A lamellar body is a membrane-bounded organelle, specialized for the storage and secretion of various substances (surfactant phospholipids, glycoproteins and acid phosphates) which are arranged in the form of tightly packed, concentric, membrane sheets or lamellae. Has some similar properties to, but is distinct from, a lysosome. GO:0000320 re-entry into mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000320 The resumption of the mitotic cell division cycle by cells that were in a quiescent or other non-dividing state. GO:0097235 obsolete positive regulation of fatty acid beta-oxidation by positive regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097235 OBSOLETE. Any process that activates or increases the frequency, rate or extent of fatty acid beta-oxidation by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. CHEBI:14280 formyl phosphate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_14280 GO:0097234 epidermal lamellar body membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097234 The lipid bilayer surrounding an epidermal lamellar body, a specialized secretory organelle found in keratinocytes and involved in the formation of an impermeable, lipid-containing membrane that serves as a water barrier and is required for correct skin barrier function. GO:0000325 plant-type vacuole biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000325 vacuole, cell cycle-independent morphology A closed structure that is completely surrounded by a unit membrane, contains liquid, and retains the same shape regardless of cell cycle phase. An example of this structure is found in Arabidopsis thaliana. GO:0000324 fungal-type vacuole biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000324 vacuole, cell cycle-correlated morphology A vacuole that has both lytic and storage functions. The fungal vacuole is a large, membrane-bounded organelle that functions as a reservoir for the storage of small molecules (including polyphosphate, amino acids, several divalent cations (e.g. calcium), other ions, and other small molecules) as well as being the primary compartment for degradation. It is an acidic compartment, containing an ensemble of acid hydrolases. At least in S. cerevisiae, there are indications that the morphology of the vacuole is variable and correlated with the cell cycle, with logarithmically growing cells having a multilobed, reticulated vacuole, while stationary phase cells contain a single large structure. GO:0097231 cell motility in response to calcium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097231 Ca2+ facilitation of cell motility|calcium ion facilitation of cell motility Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another as a result of a calcium ion stimulus. GO:0000323 lytic vacuole biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000323 A vacuole that is maintained at an acidic pH and which contains degradative enzymes, including a wide variety of acid hydrolases. GO:0097230 cell motility in response to potassium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097230 K+ facilitation of cell motility|potassium ion facilitation of cell motility Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another as a result of a potassium ion stimulus. GO:0000322 storage vacuole biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000322 A vacuole that functions primarily in the storage of materials, including nutrients, pigments, waste products, and small molecules. GO:1903469 removal of RNA primer involved in mitotic DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903469 DNA replication, removal of RNA primer involved in mitotic nuclear cell cycle DNA replication|Okazaki initiator RNA removal involved in DNA replication involved in S phase involved in mitotic cell cycle|DNA replication, removal of RNA primer involved in DNA replication involved in S phase involved in mitotic cell cycle|DNA replication, removal of RNA primer involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|Okazaki initiator RNA removal involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|DNA replication, removal of RNA primer involved in DNA replication during S phase involved in mitotic cell cycle|Okazaki initiator RNA removal involved in mitotic cell cycle DNA replication|Okazaki initiator RNA removal involved in DNA replication during S phase involved in mitotic cell cycle|Okazaki initiator RNA removal involved in DNA replication involved in S-phase involved in mitotic cell cycle|DNA replication, removal of RNA primer involved in DNA replication involved in S-phase involved in mitotic cell cycle|Okazaki initiator RNA removal involved in mitotic nuclear cell cycle DNA replication Any DNA replication, removal of RNA primer that is involved in mitotic cell cycle DNA replication. GO:1903468 positive regulation of DNA replication initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903468 positive regulation of DNA replication initiation involved in mitotic cell cycle DNA replication|activation of DNA replication initiation involved in mitotic cell cycle DNA replication|upregulation of DNA replication initiation involved in mitotic DNA replication|up-regulation of DNA replication initiation involved in mitotic cell cycle DNA replication|up-regulation of DNA replication initiation involved in mitotic DNA replication|activation of DNA replication initiation involved in mitotic DNA replication|upregulation of DNA replication initiation involved in mitotic cell cycle DNA replication|up regulation of DNA replication initiation involved in mitotic DNA replication|up regulation of DNA replication initiation involved in mitotic cell cycle DNA replication Any process that activates or increases the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication. GO:1903467 negative regulation of mitotic DNA replication initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903467 down regulation of DNA replication initiation involved in mitotic DNA replication|inhibition of DNA replication initiation involved in mitotic DNA replication|negative regulation of DNA replication initiation involved in mitotic cell cycle DNA replication|down-regulation of DNA replication initiation involved in mitotic cell cycle DNA replication|inhibition of DNA replication initiation involved in mitotic cell cycle DNA replication|down-regulation of DNA replication initiation involved in mitotic DNA replication|down regulation of DNA replication initiation involved in mitotic cell cycle DNA replication|downregulation of DNA replication initiation involved in mitotic cell cycle DNA replication|downregulation of DNA replication initiation involved in mitotic DNA replication Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication. GO:1903466 regulation of mitotic DNA replication initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903466 regulation of DNA replication initiation involved in mitotic cell cycle DNA replication Any process that modulates the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication. GO:1903465 positive regulation of mitotic cell cycle DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903465 activation of DNA replication during S phase involved in mitotic cell cycle|upregulation of mitotic cell cycle DNA replication|upregulation of DNA replication involved in S-phase involved in mitotic cell cycle|positive regulation of DNA replication involved in S phase involved in mitotic cell cycle|up-regulation of DNA replication during S phase involved in mitotic cell cycle|upregulation of mitotic nuclear cell cycle DNA replication|up regulation of DNA replication involved in S phase involved in mitotic cell cycle|upregulation of nuclear cell cycle DNA replication involved in mitotic cell cycle|up-regulation of mitotic cell cycle DNA replication|activation of mitotic cell cycle DNA replication|up-regulation of DNA replication involved in S-phase involved in mitotic cell cycle|activation of DNA replication involved in S-phase involved in mitotic cell cycle|upregulation of DNA replication during S phase involved in mitotic cell cycle|up-regulation of mitotic nuclear cell cycle DNA replication|activation of mitotic nuclear cell cycle DNA replication|upregulation of DNA replication involved in S phase involved in mitotic cell cycle|up regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle|positive regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle|up regulation of mitotic cell cycle DNA replication|positive regulation of DNA replication involved in S-phase involved in mitotic cell cycle|up regulation of DNA replication during S phase involved in mitotic cell cycle|activation of nuclear cell cycle DNA replication involved in mitotic cell cycle|up regulation of DNA replication involved in S-phase involved in mitotic cell cycle|up-regulation of DNA replication involved in S phase involved in mitotic cell cycle|positive regulation of mitotic nuclear cell cycle DNA replication|activation of DNA replication involved in S phase involved in mitotic cell cycle|positive regulation of DNA replication during S phase involved in mitotic cell cycle|up regulation of mitotic nuclear cell cycle DNA replication|up-regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle Any process that activates or increases the frequency, rate or extent of mitotic cell cycle DNA replication. GO:1903464 negative regulation of mitotic cell cycle DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903464 downregulation of mitotic nuclear cell cycle DNA replication|down regulation of DNA replication involved in S-phase involved in mitotic cell cycle|down-regulation of DNA replication involved in S phase involved in mitotic cell cycle|negative regulation of DNA replication involved in S phase involved in mitotic cell cycle|inhibition of DNA replication involved in S-phase involved in mitotic cell cycle|inhibition of nuclear cell cycle DNA replication involved in mitotic cell cycle|down regulation of mitotic nuclear cell cycle DNA replication|inhibition of mitotic nuclear cell cycle DNA replication|downregulation of DNA replication involved in S phase involved in mitotic cell cycle|inhibition of DNA replication during S phase involved in mitotic cell cycle|down regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle|down regulation of DNA replication involved in S phase involved in mitotic cell cycle|inhibition of DNA replication involved in S phase involved in mitotic cell cycle|downregulation of nuclear cell cycle DNA replication involved in mitotic cell cycle|down-regulation of mitotic cell cycle DNA replication|down regulation of DNA replication during S phase involved in mitotic cell cycle|down-regulation of DNA replication involved in S-phase involved in mitotic cell cycle|negative regulation of DNA replication involved in S-phase involved in mitotic cell cycle|downregulation of DNA replication during S phase involved in mitotic cell cycle|negative regulation of mitotic nuclear cell cycle DNA replication|down-regulation of mitotic nuclear cell cycle DNA replication|negative regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle|down-regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle|downregulation of mitotic cell cycle DNA replication|downregulation of DNA replication involved in S-phase involved in mitotic cell cycle|down regulation of mitotic cell cycle DNA replication|negative regulation of DNA replication during S phase involved in mitotic cell cycle|inhibition of mitotic cell cycle DNA replication|down-regulation of DNA replication during S phase involved in mitotic cell cycle Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle DNA replication. GO:1903474 obsolete anchoring of the mitotic actomyosin contractile ring to the plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903474 maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|cytokinetic ring anchoring involved in mitotic cell cycle|maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle OBSOLETE. A process that maintains the mitotic actinomyosin contractile ring at the plasma membrane. GO:1903473 positive regulation of mitotic actomyosin contractile ring contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903473 activation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle|positive regulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle|upregulation of mitotic actomyosin contractile ring contraction|up-regulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|activation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|up-regulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle|up regulation of mitotic actomyosin contractile ring contraction|positive regulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|activation of mitotic actomyosin contractile ring contraction|up regulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|upregulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle|up-regulation of mitotic actomyosin contractile ring contraction|upregulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|up regulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle Any process that activates or increases the frequency, rate or extent of mitotic actomyosin contractile ring contraction. CHEBI:38249 (1S,4R)-1-hydroxylimonen-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38249 GO:1903472 negative regulation of mitotic actomyosin contractile ring contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903472 negative regulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle|down-regulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle|down regulation of mitotic actomyosin contractile ring contraction|downregulation of mitotic actomyosin contractile ring contraction|negative regulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|down-regulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|inhibition of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle|down-regulation of mitotic actomyosin contractile ring contraction|downregulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|down regulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|down regulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle|inhibition of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|inhibition of mitotic actomyosin contractile ring contraction|downregulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle Any process that stops, prevents or reduces the frequency, rate or extent of mitotic actomyosin contractile ring contraction. GO:1903471 regulation of mitotic actomyosin contractile ring contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903471 regulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|regulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring contraction. CHEBI:38247 (R)-3-hydroxypalmitic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38247 GO:1903470 obsolete actomyosin contractile ring assembly involved in mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903470 contractile ring assembly involved in mitotic cell cycle|cytokinesis, actomyosin ring formation involved in mitotic cell cycle|constriction ring assembly involved in mitotic cell cycle|cytokinesis, actomyosin contractile ring formation involved in mitotic cell cycle|cytokinesis, actomyosin ring biosynthesis involved in mitotic cell cycle|cytokinesis, contractile ring assembly involved in mitotic cell cycle|cytokinesis, actomyosin contractile ring assembly involved in mitotic cell cycle OBSOLETE. Any actomyosin contractile ring assembly that is involved in mitotic cell cycle. GO:0000329 fungal-type vacuole membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000329 membrane of vacuole with cell cycle-correlated morphology|fungal-type vacuolar membrane The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae. GO:0000328 fungal-type vacuole lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000328 lumen of vacuole with cell cycle-correlated morphology The volume enclosed within the vacuolar membrane of a vacuole, the shape of which correlates with cell cycle phase. An example of this structure is found in Saccharomyces cerevisiae. GO:0000327 lytic vacuole within protein storage vacuole biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000327 A membrane-bounded compartment containing crystals of phytic acid and proteins characteristic of a lytic vacuole, found within a storage vacuole. GO:0000326 protein storage vacuole biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000326 A storage vacuole that contains a lytic vacuole; identified in plants. GO:0097237 cellular response to toxic substance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097237 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus. GO:0097236 obsolete positive regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097236 OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of zinc ions. GO:0097239 positive regulation of transcription from RNA polymerase II promoter in response to methylglyoxal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097239 Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to a methylglyoxal stimulus. GO:0097238 cellular response to methylglyoxal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097238 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. Methylglyoxal is a 2-oxoaldehyde derived from propanal. CHEBI:14272 fluoroacetaldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_14272 GO:0097244 flavonol binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097244 Interacting selectively and non-covalently with a flavonol, a flavonoid that contains a 3-hydroxy-2-phenylchromen-4-one backbone. GO:0000332 template for synthesis of G-rich strand of telomere DNA activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000332 telomerase, template|telomerase RNA Provision of the template used by reverse transcriptase to synthesize the G-rich strand of telomeric DNA. GO:0000331 contractile vacuole biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000331 Wikipedia:Contractile_vacuole central vacuole|central bladder A specialized vacuole of eukaryotic cells, especially Protozoa, that fills with water from the cytoplasm and then discharges this externally by the opening of contractile vacuole pores. One of its functions is osmoregulatory. GO:0097243 flavonoid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097243 Interacting selectively and non-covalently with a flavonoid, a compound containing two or more aromatic rings, each bearing at least one aromatic hydroxyl and connected with a carbon bridge. GO:0097246 catechin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097246 Interacting selectively and non-covalently with a catechin, a polyphenolic antioxidant plant metabolite with a flavonoid or flavan-3-ol structure. GO:0000330 plant-type vacuole lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000330 lumen of vacuole with cell cycle-independent morphology The volume enclosed within the vacuolar membrane of a vacuole that retains the same shape regardless of cell cycle phase. An example of this is found in Arabidopsis thaliana. GO:0097245 flavanol binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097245 flavan-3-ol binding Interacting selectively and non-covalently with a flavanol. GO:0000336 positive regulation of transposition, DNA-mediated biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000336 up regulation of DNA transposition|activation of DNA transposition|stimulation of DNA transposition|up-regulation of DNA transposition|positive regulation of DNA transposition|upregulation of DNA transposition Any process that activates or increases the frequency, rate or extent of DNA transposition. GO:0097240 chromosome attachment to the nuclear envelope biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097240 attachment of chromatin to nuclear envelope The process in which chromatin is anchored to the nuclear envelope. CHEBI:38260 pyrrolidines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38260 GO:0000335 negative regulation of transposition, DNA-mediated biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000335 down-regulation of DNA transposition|inhibition of DNA transposition|negative regulation of DNA transposition|down regulation of DNA transposition|downregulation of DNA transposition Any process that stops, prevents, or reduces the frequency, rate or extent of DNA transposition. GO:0000334 3-hydroxyanthranilate 3,4-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000334 KEGG_REACTION:R02665|RHEA:17953|Reactome:R-HSA-71218|MetaCyc:1.13.11.6-RXN|EC:1.13.11.6|UM-BBD_reactionID:r1027 3-hydroxyanthranilic oxygenase activity|3-hydroxyanthranilate oxygenase activity|3-hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing)|3-hydroxyanthranilic acid dioxygenase activity|3HAO|3-hydroxyanthranilic acid oxygenase activity Catalysis of the reaction: 3-hydroxyanthranilate + O(2) = cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate + H(+). GO:0097242 amyloid-beta clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097242 beta-amyloid clearance The process in which amyloid-beta is removed from extracellular brain regions by mechanisms involving cell surface receptors. GO:0097241 hematopoietic stem cell migration to bone marrow biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097241 hemopoietic stem cell migration to bone marrow|hematopoietic stem cell homing|progenitor cell homing The orderly movement of a hematopoietic stem cell into the bone marrow, and its subsequent positioning within defined functional compartments in that microenvironment. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. GO:0000333 telomerase catalytic core complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000333 TERT-TERC complex The minimal catalytic core of telomerase is a ribonucleoprotein complex composed of a catalytic reverse transcriptase subunit and an RNA subunit that provides the template for telomeric DNA addition. CHEBI:133507 beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133507 GO:1903479 mitotic actomyosin contractile ring assembly actin filament organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903479 actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|actin filament organisation involved in mitotic actomyosin contractile ring assembly|actin filament organization involved in mitotic actomyosin contractile ring assembly Any actin filament organization that is involved in mitotic actomyosin contractile ring assembly. CHEBI:133506 beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133506 CHEBI:133509 alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133509 GO:1903478 actin filament bundle convergence involved in mitotic contractile ring assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903478 actin filament bundle convergence involved in contractile ring assembly involved in mitotic cytokinesis|actin filament bundle convergence involved in cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|actin filament bundle convergence involved in mitotic actomyosin contractile ring assembly|actin filament bundle convergence involved in actomyosin contractile ring assembly involved in cytokinesis after mitosis Any actin filament bundle convergence that is involved in mitotic actomyosin contractile ring assembly. GO:1903477 mitotic contractile ring actin filament bundle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903477 actin filament bundle assembly involved in mitotic actomyosin contractile ring assembly Any actin filament bundle assembly that is involved in mitotic actomyosin contractile ring assembly. GO:1903476 protein localization to cell division site involved in mitotic actomyosin contractile ring assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903476 protein localization to cell division site involved in contractile ring assembly involved in mitotic cytokinesis|protein localisation to cell division site involved in mitotic actomyosin contractile ring assembly|protein localization to cell division site involved in actomyosin contractile ring assembly involved in cytokinesis after mitosis Any protein localization to cell division site that is involved in mitotic actomyosin contractile ring assembly. GO:1903475 mitotic actomyosin contractile ring assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903475 actomyosin contractile ring assembly involved in cytokinesis after mitosis|cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|contractile ring assembly involved in mitotic cytokinesis Any actomyosin contractile ring assembly that is involved in mitotic cytokinesis. GO:1903485 obsolete positive regulation of maintenance of mitotic actomyosin contractile ring localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903485 positive regulation of cytokinetic ring anchoring involved in mitotic cell cycle|up regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle|upregulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|positive regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle|up-regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|activation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|activation of cytokinetic ring anchoring involved in mitotic cell cycle|up regulation of maintenance of mitotic actomyosin contractile ring localization|activation of maintenance of mitotic actomyosin contractile ring localization|activation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle|up-regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|up-regulation of cytokinetic ring anchoring involved in mitotic cell cycle|activation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|positive regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|up-regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle|up regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|up-regulation of maintenance of mitotic actomyosin contractile ring localization|upregulation of cytokinetic ring anchoring involved in mitotic cell cycle|positive regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|up regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|upregulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle|upregulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|upregulation of maintenance of mitotic actomyosin contractile ring localization|up regulation of cytokinetic ring anchoring involved in mitotic cell cycle OBSOLETE. Any process that activates or increases the frequency, rate or extent of maintenance of mitotic actomyosin contractile ring localization. GO:1903484 obsolete negative regulation of maintenance of mitotic actomyosin contractile ring localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903484 inhibition of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|down regulation of maintenance of mitotic actomyosin contractile ring localization|negative regulation of cytokinetic ring anchoring involved in mitotic cell cycle|downregulation of maintenance of mitotic actomyosin contractile ring localization|down-regulation of cytokinetic ring anchoring involved in mitotic cell cycle|down-regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle|negative regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle|negative regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|down-regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|down-regulation of maintenance of mitotic actomyosin contractile ring localization|inhibition of cytokinetic ring anchoring involved in mitotic cell cycle|down-regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|negative regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|inhibition of maintenance of mitotic actomyosin contractile ring localization|downregulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|inhibition of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle|down regulation of cytokinetic ring anchoring involved in mitotic cell cycle|down regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|inhibition of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|downregulation of cytokinetic ring anchoring involved in mitotic cell cycle|down regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle|downregulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|down regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|downregulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic actomyosin contractile ring localization. GO:1903483 obsolete regulation of maintenance of mitotic actomyosin contractile ring localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903483 regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|regulation of cytokinetic ring anchoring involved in mitotic cell cycle|regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle OBSOLETE. Any process that modulates the frequency, rate or extent of maintenance of mitotic actomyosin contractile ring localization. CHEBI:38259 divinyl chlorophyllide a biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38259 GO:1903482 positive regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903482 upregulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|upregulation of actin filament organization involved in mitotic actomyosin contractile ring assembly|upregulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly|up-regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly|up regulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|activation of actin filament organization involved in mitotic actomyosin contractile ring assembly|activation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|positive regulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|up-regulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly|activation of actin filament organisation involved in mitotic actomyosin contractile ring assembly|up regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly|up-regulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|positive regulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly|up regulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly Any process that activates or increases the frequency, rate or extent of actin filament organization involved in mitotic actomyosin contractile ring assembly. GO:1903481 negative regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903481 downregulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly|down regulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|down regulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly|inhibition of actin filament organisation involved in mitotic actomyosin contractile ring assembly|downregulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|down-regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly|negative regulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|down-regulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|inhibition of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|negative regulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly|down-regulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly|downregulation of actin filament organization involved in mitotic actomyosin contractile ring assembly|down regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly|inhibition of actin filament organization involved in mitotic actomyosin contractile ring assembly Any process that stops, prevents or reduces the frequency, rate or extent of actin filament organization involved in mitotic actomyosin contractile ring assembly. CHEBI:14268 flavonol 3-O-glycoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_14268 CHEBI:133501 3-(3-methylthio)propylmalate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133501 GO:1903480 regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903480 regulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly|regulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis Any process that modulates the frequency, rate or extent of actin filament organization involved in mitotic actomyosin contractile ring assembly. CHEBI:133500 2-(2-methylthio)propylmaleate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133500 CHEBI:133503 beta-D-GalpNAc-(1->4)-[alpha-Neup5Gc-(2->3)]-beta-D-Galp biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133503 GO:0000339 RNA cap binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000339 snRNA cap binding|binding to mRNA cap|mRNA cap binding Interacting selectively and non-covalently with a 7-methylguanosine (m7G) group or derivative located at the 5' end of an RNA molecule. CHEBI:38252 phorbines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38252 GO:0000338 protein deneddylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000338 cullin deneddylation The removal of a ubiquitin-like protein of the NEDD8 type from a protein. CHEBI:38251 magnesium tetrapyrrole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38251 GO:0000337 regulation of transposition, DNA-mediated biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000337 regulation of DNA transposition Any process that modulates the frequency, rate or extent of DNA transposition, the process of transposing (moving to a different location) a segment of a chromosome or a piece of a DNA molecule. GO:0097248 maintenance of protein location in cell cortex of cell tip biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097248 A process in which a protein or protein complex is maintained in a specific location in the cell cortex of a cell tip, and is prevented from moving elsewhere. The cell cortex of a cell tip is the region directly beneath the plasma membrane at either end of the longest axis of a cylindrical or elongated cell. CHEBI:38257 pheophorbide a biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38257 GO:0097247 epigallocatechin 3-gallate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097247 catechin gallate binding|EGCG binding Interacting selectively and non-covalently with epigallocatechin 3-gallate, a compound that is a gallic acid ester of a catechin. CHEBI:14261 feruloyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_14261 CHEBI:38254 pheophorbide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38254 GO:0097249 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0097249 GO:0097211 cellular response to gonadotropin-releasing hormone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097211 cellular response to gonadotrophin-releasing hormone|cellular response to GnRH Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin-releasing hormone stimulus. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus. GO:0097210 response to gonadotropin-releasing hormone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097210 response to GnRH Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin-releasing hormone stimulus. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus. GO:0097213 regulation of lysosomal membrane permeability biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097213 regulation of lysosome membrane permeability Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane. GO:0097212 lysosomal membrane organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097212 lysosome membrane organization|lysosomal membrane organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosomal membrane. A lysosomal membrane is the lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm. GO:0000303 response to superoxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000303 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion. GO:0000302 response to reactive oxygen species biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000302 response to AOS|response to reactive oxidative species|response to reactive oxygen intermediate|response to ROS|response to active oxygen species|response to ROI Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals. GO:0000301 retrograde transport, vesicle recycling within Golgi biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000301 retrograde (vesicle recycling within Golgi) transport The retrograde movement of substances within the Golgi, mediated by COP I vesicles. Cis-Golgi vesicles are constantly moving forward through the Golgi stack by cisternal progression, eventually becoming trans-Golgi vesicles. They then selectively transport membrane and luminal proteins from the trans- to the medial-Golgi while leaving others behind in the trans-Golgi cisternae; similarly, they selectively move proteins from the medial- to the cis-Golgi. GO:0000300 obsolete peripheral to membrane of membrane fraction biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000300 peripheral to membrane of membrane fraction OBSOLETE. Peripheral to that fraction of cells, prepared by disruptive biochemical methods, that includes the plasma and other membranes; can be extracted from membrane fraction with high concentrations of salt or high pH. GO:1903489 positive regulation of lactation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903489 upregulation of lactation|up regulation of lactation|activation of lactation|up-regulation of lactation Any process that activates or increases the frequency, rate or extent of lactation. GO:1903488 negative regulation of lactation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903488 down regulation of lactation|downregulation of lactation|down-regulation of lactation|inhibition of lactation Any process that stops, prevents or reduces the frequency, rate or extent of lactation. GO:1903487 regulation of lactation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903487 Any process that modulates the frequency, rate or extent of lactation. GO:1903486 establishment of mitotic actomyosin contractile ring localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903486 establishment of actomyosin contractile ring localization involved in mitotic cell cycle Any establishment of actomyosin contractile ring localization that is involved in mitotic cell cycle. GO:1903496 response to 11-deoxycorticosterone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903496 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 11-deoxycorticosterone stimulus. GO:1903495 cellular response to dehydroepiandrosterone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903495 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dehydroepiandrosterone stimulus. GO:1903494 response to dehydroepiandrosterone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903494 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dehydroepiandrosterone stimulus. CHEBI:38226 1,2-dithiolane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38226 GO:1903493 response to clopidogrel biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903493 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a clopidogrel stimulus. Clopidogrel is a is an oral, thienopyridine-class antiplatelet agent used to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease. GO:1903492 response to acetylsalicylate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903492 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aspirin (acetylsalicylate) stimulus. Aspirin is a non-steroidal anti-inflammatory drug with moA cyclooxygenase inhibitor activity. GO:1903491 response to simvastatin biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_1903491 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a simvastatin stimulus. Simvastatin is a statin used as a cholesterol-lowering and anti-cardiovascular disease drug. GO:1903490 positive regulation of mitotic cytokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903490 upregulation of cytokinesis after mitosis|up-regulation of mitotic cytokinesis|up regulation of cytokinesis after mitosis|upregulation of mitotic cytokinesis|positive regulation of cytokinesis after mitosis|activation of cytokinesis after mitosis|up regulation of mitotic cytokinesis|up-regulation of cytokinesis after mitosis|activation of mitotic cytokinesis Any process that activates or increases the frequency, rate or extent of mitotic cytokinesis. CHEBI:38229 solanapyrone A biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38229 GO:0000307 cyclin-dependent protein kinase holoenzyme complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0000307 CDK holoenzyme Cyclin-dependent protein kinases (CDKs) are enzyme complexes that contain a kinase catalytic subunit associated with a regulatory cyclin partner. GO:0097219 compound sieve plate biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097219 A sieve plate that contains several specialized sieve areas in either a scalariform or reticulate arrangement. GO:0000306 extrinsic component of vacuolar membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000306 extrinsic to vacuolar membrane The component of a vacuolar membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:0097218 sieve plate biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097218 A part of the cell wall of a sieve tube member that bears one or more highly specialized sieve areas. GO:0000305 response to oxygen radical biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000305 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion. GO:0000304 response to singlet oxygen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000304 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a singlet oxygen stimulus. Singlet oxygen is a dioxygen (O2) molecule in which two 2p electrons have similar spin. Singlet oxygen is more highly reactive than the form in which these electrons are of opposite spin, and it is produced in mutant chloroplasts lacking carotenoids and by leukocytes during metabolic burst. GO:0097215 negative regulation of lysosomal membrane permeability biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097215 negative regulation of lysosome membrane permeability Any process that decreases the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane. CHEBI:38224 fumonisin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38224 GO:0097214 positive regulation of lysosomal membrane permeability biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097214 positive regulation of lysosome membrane permeability Any process that increases the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane. GO:0000309 nicotinamide-nucleotide adenylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000309 RHEA:21360|MetaCyc:2.7.7.1-RXN|Reactome:R-HSA-8939959|EC:2.7.7.1 ATP:nicotinamide-nucleotide adenylyltransferase activity|NAD(+) pyrophosphorylase activity|nicotinamide adenine dinucleotide pyrophosphorylase activity|NAD(+) diphosphorylase activity|adenosine triphosphate-nicotinamide mononucleotide transadenylase activity|nicotinamide mononucleotide adenylyltransferase activity|NMNAT activity|NMN adenylyltransferase activity|NAD+ pyrophosphorylase activity|NAD+ diphosphorylase activity|diphosphopyridine nucleotide pyrophosphorylase activity|ATP:NMN adenylyltransferase activity Catalysis of the reaction: ATP + nicotinamide nucleotide = diphosphate + NAD+. GO:0097217 sieve area biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097217 A pit-like area in the cell wall of a sieve element; contains pores lined with callose and occupied by strands of protoplasmic material that interconnect the protoplasts of contiguous sieve elements. CHEBI:38222 hydrocarbyl anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38222 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000308 CDK holoenzyme Cyclin-dependent protein kinase (CDK) complex found in the cytoplasm. GO:0097216 guanosine tetraphosphate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097216 5'-ppGpp-3' binding Interacting selectively and non-covalently with guanosine tetraphosphate (5'-ppGpp-3'), a guanosine bisphosphate having diphosphate groups at both the 3' and 5'-positions. CHEBI:38221 fumonisin B1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38221 GO:0000310 xanthine phosphoribosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000310 RHEA:10800|EC:2.4.2.22|MetaCyc:XANPRIBOSYLTRAN-RXN XMP pyrophosphorylase activity|xanthine-guanine phosphoribosyltransferase activity|xanthosine 5'-phosphate pyrophosphorylase activity|Xan phosphoribosyltransferase activity|5-phospho-alpha-D-ribose-1-diphosphate:xanthine phospho-D-ribosyltransferase activity|xanthylic pyrophosphorylase activity|xanthylate pyrophosphorylase activity|XMP:diphosphate 5-phospho-alpha-D-ribosyltransferase activity Catalysis of the reaction: 5-phospho-alpha-D-ribose 1-diphosphate + xanthine = (9-D-ribosylxanthine)-5'-phosphate + diphosphate. GO:0097222 mitochondrial mRNA polyadenylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097222 The enzymatic addition of a sequence of 40-60 adenylyl residues at the 3' end of a eukaryotic mitochondrial mRNA primary transcript. Mitochondria contain both stabilizing and destabilizing poly(A) tails. GO:0097221 M/G1 phase-specific MADS box-forkhead transcription factor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097221 pombe cell cycle box binding factor complex|PCB binding factor complex|PBF transcription complex|PBF complex A protein complex that contains a MADS-box protein and two forkhead domain proteins, and binds to and regulates transcription from promoters of genes transcribed during the M/G1 transition of the cell cycle. In Schizosaccharomyces pombe, the complex contains the MADS-box protein Mbx1 and two forkhead proteins, Sep1 and Fkh2. GO:0097224 sperm connecting piece biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097224 The segment of the sperm flagellum that attaches to the implantation fossa of the nucleus in the sperm head; from the remnant of the centriole at this point, the axoneme extends throughout the length of the flagellum. GO:0097223 obsolete sperm part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0097223 OBSOLETE. Any constituent part of a sperm, a mature male germ cell that develops from a spermatid. GO:0000314 organellar small ribosomal subunit biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000314 The smaller of the two subunits of an organellar ribosome. GO:0000313 organellar ribosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000313 A ribosome contained within a subcellular membrane-bounded organelle. GO:0097220 simple sieve plate biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097220 A sieve plate that contains a single specialized sieve area. GO:0000312 plastid small ribosomal subunit biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000312 The smaller of the two subunits of a plastid ribosome. GO:0000311 plastid large ribosomal subunit biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000311 The larger of the two subunits of a plastid ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site). GO:1903499 regulation of mitotic actomyosin contractile ring assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903499 regulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis|regulation of contractile ring assembly involved in mitotic cytokinesis|regulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|regulation of mitotic cytokinesis, actomyosin contractile ring assembly Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring assembly. GO:1903498 bundle sheath cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903498 The process in which a relatively unspecialized cell acquires the specialized features of a bundle sheath cell. GO:1903497 cellular response to 11-deoxycorticosterone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903497 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 11-deoxycorticosterone stimulus. CHEBI:38238 prosolanapyrone II biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38238 CHEBI:38237 prosolanapyrone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38237 GO:0000318 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000318 CHEBI:38231 phytotoxin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38231 CHEBI:38230 solanapyrone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38230 GO:0000317 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000317 GO:0097229 sperm end piece biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097229 The short tip of the sperm flagellum, adjacent to the sperm principal piece and furthest from the sperm head, which contains only the axoneme surrounded by the plasma membrane. GO:0000316 sulfite transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000316 sulphite transport The directed movement of sulfite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0000315 organellar large ribosomal subunit biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000315 The larger of the two subunits of an organellar ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site). GO:0097226 sperm mitochondrial sheath biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097226 The tightly packed helical sheath of ATP-producing mitochondria restricted to the midpiece of the sperm flagellum. GO:0097225 sperm midpiece biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097225 The highly organized segment of the sperm flagellum which begins at the connecting piece and is characterized by the presence of 9 outer dense fibers (ODFs) that lie outside each of the 9 outer axonemal microtubule doublets and by a sheath of mitochondria that encloses the ODFs and the axoneme; the midpiece terminates about one-fourth of the way down the sperm flagellum at the annulus, which marks the beginning of the principal piece. CHEBI:38234 DNA polymerase inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38234 GO:0097228 sperm principal piece biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097228 The segment of the sperm flagellum where the mitochondrial sheath ends, and the outer dense fibers (ODFs) associated with outer axonemal doublets 3 and 8 are replaced by the 2 longitudinal columns of the fibrous sheath (FS) which run the length of the principal piece and are stabilized by circumferential ribs. The principal piece makes up ~2/3 of the length of the sperm flagellum and is defined by the presence of the FS and of only 7 (rather than 9) ODFs which taper and then terminate near the distal end of the principal piece. GO:0097227 sperm annulus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097227 The ring-like, filamentous structure located at the distal end of the midpiece of the sperm flagellum; the annulus is thought to form a diffusion barrier between the midpiece and the principal piece and serve as a stabilizing structure for tail rigidity. GO:0000319 sulfite transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000319 sulphite transporter activity Enables the transfer of sulfite ions from one side of a membrane to the other. GO:0097277 cellular urea homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097277 Any biological process involved in the maintenance of an internal steady state of urea at the level of the cell. GO:0097276 cellular creatinine homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097276 Any biological process involved in the maintenance of an internal steady state of creatinine at the level of the cell. GO:0097279 histamine secretion mediated by IgE immunoglobulin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097279 Ig-mediated histamine release|histamine secretion mediated by IgE antibody Histamine release triggered by the binding of an antigen to an IgE immunoglobulin bound to the cell surface. An example is mast cell histamine degranulation as a result of exposure of mast cell-bound IgE to alder tree pollen. GO:0097278 complement-dependent cytotoxicity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097278 Cell killing caused by the membrane attack complex formed following complement activation. CHEBI:28887 dimethyl ether biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28887 GO:0097273 creatinine homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097273 Any biological process involved in the maintenance of an internal steady state of creatinine. GO:0097272 ammonium homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097272 ammonia homeostasis Any biological process involved in the maintenance of an internal steady state of ammonium. GO:0097275 cellular ammonium homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097275 cellular ammonia homeostasis Any biological process involved in the maintenance of an internal steady state of ammonium at the level of the cell. CHEBI:28889 5,6,7,8-tetrahydropteridine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28889 GO:0097274 urea homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097274 Any biological process involved in the maintenance of an internal steady state of urea. GO:0097271 protein localization to bud neck biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097271 protein localization to cellular bud neck|protein localisation to bud neck A process in which a protein is transported to, or maintained at, a location within a cellular bud neck. CHEBI:28885 butan-1-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28885 GO:0097270 dishabituation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097270 The temporary recovery of response to a stimulus when a novel stimulus is added. CHEBI:28884 N-phenylacetamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28884 CHEBI:28881 2-acetamido-3-O-[(1R)-1-carboxylatoethyl]-2-deoxy-D-glucopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28881 CHEBI:28880 (S)-mevalonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28880 CHEBI:38206 chlorophyllide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38206 CHEBI:38209 chlorophyllide b biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38209 CHEBI:38208 aminoacylpyridine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38208 CHEBI:38201 bacteriochlorophyll biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38201 GO:0097288 7-cyano-7-deazaguanine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097288 7-cyano-7-deazaguanine anabolism|7-cyano-7-deazaguanine biosynthesis|7-cyano-7-deazaguanine synthesis|7-cyano-7-deazaguanine formation The chemical reactions and pathways resulting in the formation of the Q nucleoside precursor 7-cyano-7-deazaguanine, also known as 2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile or preQo. GO:0097287 7-cyano-7-deazaguanine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097287 7-cyano-7-deazaguanine metabolism The chemical reactions and pathways involving the Q nucleoside precursor 7-cyano-7-deazaguanine, also known as 2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile or preQo. GO:0097289 alpha-ribazole metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097289 alpha-ribazole metabolism The chemical reactions and pathways involving alpha-ribazole, the benzimidazole nucleoside in adenosyl cobalamin (vitamin B12). GO:0097284 hepatocyte apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097284 hepatocyte apoptosis Any apoptotic process in a hepatocyte, the main structural component of the liver. CHEBI:28898 P(1),P(5)-bis(5'-adenosyl) pentaphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28898 GO:0097283 keratinocyte apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097283 keratinocyte apoptosis Any apoptotic process in a keratinocyte. A keratinocyte is an epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. CHEBI:28897 pentadecane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28897 GO:0097286 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0097286 GO:0097285 obsolete cell-type specific apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097285 cell-type specific apoptosis OBSOLETE. Any apoptotic process in a specific cell type. GO:0097280 histamine secretion mediated by immunoglobulin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097280 Histamine release triggered by the binding of an antigen to an immunoglobulin bound to the cell surface. CHEBI:28894 1-O-alkyl-2-O-arachidonoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28894 GO:0097282 immunoglobulin-mediated neutralization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097282 antibody-mediated neutralization The inhibition of an antigen's biological effects by antibody binding to it. An example is neutralization of diphtheria toxin by preventing its entry into human cells via the binding of antibody specific for diphtheria toxin. GO:0097281 immune complex formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097281 antibody-mediated agglutination The process that gives rise to an immune complex. Immune complexes are clusters of antibodies bound to antigen, to which complement may also be fixed, and which may precipitate or remain in solution. Examples are the clumping of cells such as bacteria or red blood cells in the presence of an antibody, precipitation of a toxin after an antibody binds to it, and clumping of viral particles as a result of antibody binding to the virus. CHEBI:28895 3'-UMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28895 CHEBI:28890 coenzyme B biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28890 CHEBI:28892 ganglioside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28892 CHEBI:28891 oxanthrene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28891 CHEBI:38215 calcium channel blocker biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38215 GO:0097255 R2TP complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097255 A highly conserved protein complex comprised of two ATP-dependent DNA helicases (Rvb1p and Rvb2p in yeast, Pontin52 and Reptin52 in humans), Pih1p in yeast or PIH1D1 in humans, and Tah1 in yeast or RPAP3 in humans. The complex associates with Hsp90 and is thought to have a role in assembly of large protein or protein/nucleic acid complexes. In this role it is involved in multiple processes such as box C/D snoRNP biogenesis, phosphatidylinositol-3 kinase-related protein kinase (PIKK) signaling, RNA polymerase II assembly, and others. CHEBI:28869 menadione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28869 GO:0097254 renal tubular secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097254 Secretion of substances from peritubular capillaries into the renal tubules to be incorporated subsequently into the urine. Substances that are secreted include organic anions, ammonia, potassium and drugs. CHEBI:28868 fatty acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28868 GO:0097257 leukotriene B4 12-hydroxy dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097257 Reactome:R-HSA-2161567|RHEA:50608 leukotriene B4 12-hydroxydehydrogenase activity Catalysis of the reaction: leukotriene B4 + NADP(+) = 12-oxo-leukotriene B4 + NADPH + H(+). GO:0097256 phenyllactate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097256 Catalysis of the oxidation of phenyllactate to produce phenylpyruvate. GO:0014909 smooth muscle cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014909 The orderly movement of a smooth muscle cell from one site to another, often during the development of a multicellular organism. GO:0097251 leukotriene B4 biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097251 leukotriene B4 biosynthesis|LTB4 formation|leukotriene B4 anabolism|leukotriene B4 synthesis|LTB4 anabolism|leukotriene B4 formation|LTB4 biosynthesis|LTB4 synthesis The chemical reactions and pathways resulting in the formation of leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents. CHEBI:28865 taurocholic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28865 GO:0097250 mitochondrial respirasome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097250 mitochondrial respiratory chain supercomplex assembly|mitochondrial respiratory supercomplex assembly The aggregation, arrangement and bonding together of a set of respiratory enzyme complexes of the mitochondrial inner membrane (including, for example, complex II, complex III, complex IV) to form a large supercomplex. CHEBI:28864 tobramycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28864 CHEBI:28867 O-propanoylcarnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28867 GO:0097253 beta-hydroxybutyrate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097253 (R)-3-hydroxybutyrate transmembrane transporter activity|3-hydroxybutanoic acid transmembrane transporter activity Enables the transfer of beta-hydroxybutyrate from one side of a membrane to the other. Beta-hydroxybutyrate is the conjugate base of (R)-3-hydroxybutyric acid. GO:0097252 oligodendrocyte apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097252 oligodendrocyte apoptosis Any apoptotic process in an oligodendrocyte. Oligodendrocytes belong to a class of large neuroglial (macroglial) cells in the central nervous system, where they form the insulating myelin sheath of axons. CHEBI:28866 tetracosanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28866 GO:0014904 myotube cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014904 The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. CHEBI:28861 gibberellin A8 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28861 CHEBI:28860 beta-D-glucuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28860 GO:0014902 myotube differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014902 The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. CHEBI:28863 flavanones biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28863 GO:0014901 satellite cell activation involved in skeletal muscle regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014901 The process that initiates skeletal muscle satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage. CHEBI:28862 dGDP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28862 GO:0014908 myotube differentiation involved in skeletal muscle regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014908 The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. This process occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. GO:0014906 myotube cell development involved in skeletal muscle regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014906 The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. This occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. GO:0014905 myoblast fusion involved in skeletal muscle regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014905 A process in which non-proliferating myoblasts, after migrating to the site of injury, fuse into existing damaged fibers or fuse to myotubes to form new fibers, as part of the process of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. GO:0014900 muscle hyperplasia biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014900 A muscle system process that results in an increase in cell number by cell division, often leading to an increase in the size of an organ. GO:0097259 20-aldehyde-leukotriene B4 20-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097259 Reactome:R-HSA-2161792|Reactome:R-HSA-2161979 Catalysis of the reaction: 20-aldehyde-leukotriene B4 + O2 + NADPH + H(+) = 20-carboxy-leukotriene B4 + H2O + NADP(+). GO:0097258 20-hydroxy-leukotriene B4 omega oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097258 Reactome:R-HSA-2161745 20-hydroxy-leukotriene B4 omega-oxidation|20-hydroxy-leukotriene B4 omega-oxidase activity Catalysis of the reaction: 20-hydroxy-leukotriene B4 + O2 + NADPH + H(+) = 20-aldehyde-leukotriene B4 + 2H2O + NADP(+). GO:0097266 phenylacetyl-CoA 1,2-epoxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097266 KEGG_REACTION:R09838|RHEA:32171|EC:1.14.13.149 phenylacetyl-CoA epoxidase activity|ring 1,2-phenylacetyl-CoA epoxidase activity|phenylacetyl-CoA monooxygenase activity Catalysis of the reaction: phenylacetyl-CoA + H(+) + NADPH + O2 = 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + H2O + NADP(+). GO:0097265 5(S)-hydroxyeicosatetraenoic acid dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097265 Reactome:R-HSA-2161776 5-HETE dehydrogenase activity|5(S)-HETE dehydrogenase activity|5-hydroxy-eicosatetraenoic acid dehydrogenase activity Catalysis of the reaction: 5-HETE + NADP(+) = 5-oxo-ETE + NADPH + H(+). CHEBI:28879 9-O-acetylneuraminic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28879 GO:0097268 cytoophidium biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097268 A subcellular filamentary structure where CTP synthase is compartmentalized in a range of organisms including bacteria, yeast, fruit fly, rat and human. GO:0097267 omega-hydroxylase P450 pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097267 P450 omega-hydroxylase pathway The chemical reactions and pathways by which arachidonic acid is converted to other compounds initially by omega-hydroxylation. GO:0097262 eoxin D4 synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097262 Reactome:R-HSA-2161945 Catalysis of the reaction: eoxin C4 = eoxin D4 + 5-L-glutamyl amino acid. GO:0097261 eoxin C4 synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097261 Reactome:R-HSA-2161768 Catalysis of the reaction: eoxin A4 + glutathione = eoxin C4. CHEBI:28875 tetradecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28875 CHEBI:28878 dodecan-1-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28878 GO:0097264 self proteolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097264 autolysis|self-proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds. GO:0097263 eoxin E4 synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097263 Reactome:R-HSA-2161868 Catalysis of the reaction: eoxin D4 + H20 = eoxin E4 + glycine. GO:0014915 regulation of muscle filament sliding speed involved in regulation of the velocity of shortening in skeletal muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014915 Any process that modulates the velocity of muscle filament sliding, and consequently contributes to the regulation of the velocity of shortening of skeletal muscle contraction. GO:0014914 myoblast maturation involved in muscle regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014914 A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast cell to attain its fully functional state involved in muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. GO:0097260 eoxin A4 synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097260 Reactome:R-HSA-2162019 Catalysis of the reaction: leukotriene A4 = eoxin A4. CHEBI:28874 phosphatidylinositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28874 GO:0014912 negative regulation of smooth muscle cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014912 Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration. CHEBI:28873 cis-2-coumaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28873 GO:0014918 obsolete positive regulation of natriuresis by pressure natriuresis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014918 positive regulation of natriuresis by pressure natriuresis OBSOLETE. The process in which pressure natriuresis increases rate of natriuresis. GO:0014917 obsolete positive regulation of diuresis by pressure natriuresis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014917 positive regulation of diuresis by pressure natriuresis OBSOLETE. The process in which pressure natriuresis increases the rate of diuresis. CHEBI:28870 1-O-all-trans-retinoyl-beta-glucuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28870 GO:0014916 regulation of lung blood pressure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014916 regulation of pulmonary blood pressure The process that modulates the force with which blood travels through the lungs. The process is controlled by a balance of processes that increase pressure and decrease pressure. GO:0014911 positive regulation of smooth muscle cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014911 Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration. GO:0014910 regulation of smooth muscle cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014910 Any process that modulates the frequency, rate or extent of smooth muscle cell migration. GO:0097269 all-trans-decaprenyl-diphosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097269 Reactome:R-HSA-2162253|RHEA:27802|EC:2.5.1.91 (2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase activity|2-trans,6-trans-farnesyl diphosphate activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + all-trans-decaprenyl diphosphate. GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000288 nuclear mRNA catabolic process, deadenylation-dependent decay|mRNA catabolic process, deadenylation-dependent|mRNA catabolism, deadenylation-dependent|mRNA breakdown, deadenylation-dependent decay|mRNA degradation, deadenylation-dependent decay|mRNA catabolic process, deadenylylation-dependent|deadenylation-dependent mRNA decay|mRNA catabolism, deadenylylation-dependent A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability. GO:0048222 glycoprotein network biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0048222 Wikipedia:Extensin extensin An extracellular matrix part that consists of cross-linked glycoproteins. GO:0000287 magnesium ion binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000287 magnesium binding Interacting selectively and non-covalently with magnesium (Mg) ions. GO:0048221 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048221 GO:0000286 alanine dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000286 EC:1.4.1.1|MetaCyc:ALANINE-DEHYDROGENASE-RXN|RHEA:18405 L-alanine dehydrogenase activity|NAD-dependent alanine dehydrogenase activity|NADH-dependent alanine dehydrogenase activity|alanine oxidoreductase activity|alpha-alanine dehydrogenase activity|NAD-linked alanine dehydrogenase activity|AlaDH|L-alanine:NAD+ oxidoreductase (deaminating) Catalysis of the reaction: L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH + H(+). GO:0048220 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048220 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000285 Reactome:R-HSA-1676168|EC:2.7.1.150|Reactome:R-HSA-1675921|Reactome:R-HSA-1676134|Reactome:R-HSA-1675910|RHEA:13609|KEGG_REACTION:R05802|MetaCyc:2.7.1.150-RXN type III PIP kinase activity|phosphatidylinositol-3-phosphate 5-kinase activity|phosphatidylinositol 3-phosphate 5-kinase activity|ATP:1-phosphatidyl-1D-myo-inositol-3-phosphate 5-phosphotransferase activity Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + ADP + 2 H(+). CHEBI:63171 mononitrotoluene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63171 CHEBI:87141 3-oxocholesta-4,24-dien-26-oyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87141 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000289 nuclear mRNA poly(A) tail shortening|3' to 5' mRNA deadenylation|mRNA deadenylation Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length. GO:0000280 nuclear division biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0000280 karyokinesis The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei. GO:0048229 gametophyte development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048229 gametogenesis The process whose specific outcome is the progression of the gametophyte over time, from its formation to the mature structure. The gametophyte is the gamete-producing individual or phase in the life cycle having alternation of generations. An example of this process is found in Arabidopsis thaliana. CHEBI:87142 N-myristoylglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87142 GO:0048228 obsolete actin cortical patch distribution biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048228 actin cortical patch distribution OBSOLETE. Any process that establishes the spatial arrangement of actin cortical patches. An actin cortical patch is a discrete actin-containing structure found at the plasma membrane in fungal cells. GO:0048227 plasma membrane to endosome transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048227 Transport of a vesicle from the plasma membrane to the endosome. CHEBI:63173 T-cell proliferation inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63173 GO:0000284 obsolete shmoo orientation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000284 shmoo orientation OBSOLETE. (Was not defined before being made obsolete). GO:0048226 Casparian strip biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0048226 Wikipedia:Casparian_strip Region of plant cell wall specialised to act as a seal to prevent back leakage of secreted material (analogous to tight junction between epithelial cells). Found particularly where root parenchymal cells secrete solutes into xylem vessels. The barrier is composed of suberin; a fatty substance, containing long chain fatty acids and fatty esters, also found in the cell walls of cork cells (phellem) in higher plants. GO:0048225 suberin network biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0048225 An extracellular matrix part that consists of fatty acid-derived polymers, including both aromatic and aliphatic components. The suberin network is found in specialized plant cell walls, where it is laid down between the primary wall and plasma membrane, forms protective and wound-healing layers, and provides a water-impermeable diffusion barrier. GO:0000283 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000283 GO:0000282 cellular bud site selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000282 bud site selection/establishment of cell polarity The specification of the site where a daughter cell will form, in organisms that reproduce by budding. An example of this process is found in Saccharomyces cerevisiae. GO:0048224 lignin network biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0048224 An extracellular matrix part that consists of lignin in the form of a three-dimensional polymeric network. Lignins are complex racemic aromatic heteropolymers derived from a variety of phenylpropane monomers coupled together by an assortment of carbon-carbon and ether linkages. Lignin is crucial for structural integrity of the cell wall and stiffness and strength of the stem. In addition, lignin waterproofs the cell wall, enabling transport of water and solutes through the vascular system, and plays a role in protecting plants against pathogens. CHEBI:63178 (13R)-edaxadiene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63178 GO:0000281 mitotic cytokinesis biolink:BiologicalProcess go-plus goslim_pombe http://purl.obolibrary.org/obo/GO_0000281 cytokinesis after mitosis A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells. GO:0048223 hemicellulose network biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0048223 Network composed of hemicelluloses; members of a class of plant cell wall polysaccharide that cannot be extracted from the wall by hot water or chelating agents, but can be extracted by aqueous alkali. Includes xylan, glucuronoxylan, arabinoxylan, arabinogalactan II, glucomannan, xyloglucan and galactomannan. CHEBI:63177 11alpha-hydroxy-beta-amyrin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63177 CHEBI:133574 5-hydroxylysinium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133574 CHEBI:133575 N-acyl-gamma-aminobutyrate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133575 CHEBI:133577 2-hydroxy-4-methylvalerate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133577 GO:0048233 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048233 GO:0000299 obsolete integral to membrane of membrane fraction biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000299 integral to membrane of membrane fraction OBSOLETE. Integral to that fraction of cells, prepared by disruptive biochemical methods, that includes the plasma and other membranes; require detergents, such as Triton X-100, to be released from membranes. GO:0048232 male gamete generation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048232 Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction. GO:0000298 endopolyphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000298 EC:3.6.1.10|RHEA:22452|MetaCyc:ENDOPOLYPHOSPHATASE-RXN polyphosphatase activity|metaphosphatase activity|polyphosphate polyphosphohydrolase activity|polyphosphate depolymerase activity|polymetaphosphatase activity Catalysis of the reaction: polyphosphate + n H2O = (n+1) oligophosphate. The product contains 4 or 5 phosphate residues. GO:0048231 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048231 GO:0000297 spermine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000297 Enables the transfer of spermine from one side of a membrane to the other. Spermine is a polybasic amine found in human sperm, in ribosomes and in some viruses, which is involved in nucleic acid packaging. Synthesis is regulated by ornithine decarboxylase which plays a key role in control of DNA replication. GO:0000296 spermine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000296 The directed movement of spermine, N,N-bis(3-aminopropyl)-1,4-diaminobutane, a polyamine formed by the transfer of a propylamine group from decarboxylated S-adenosylmethionine to spermidine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0048230 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048230 CHEBI:63180 (13S)-edaxadiene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63180 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000291 nuclear mRNA catabolic process, exonucleolytic|mRNA degradation, exonucleolytic|mRNA breakdown, exonucleolytic|exonucleolytic degradation of mRNA The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 5'-cap or the 3'-poly(A) tail. GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000290 deadenylation-dependent decapping of nuclear mRNA|deadenylylation-dependent decapping Cleavage of the 5'-cap of a nuclear mRNA triggered by shortening of the poly(A) tail to below a minimum functional length. CHEBI:87131 O-(S-L-2-amino-6-adipoylpantetheine-4'-phosphoryl)-L-serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87131 GO:0048239 negative regulation of DNA recombination at telomere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048239 downregulation of telomeric recombination at telomere|negative regulation of telomeric recombination at telomere|suppression of telomeric recombination at telomere|down-regulation of telomeric recombination at telomere|inhibition of telomeric recombination at telomere|down regulation of telomeric recombination at telomere Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination within the telomere. CHEBI:63184 11-oxo-beta-amyrin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63184 GO:0048238 smooth endoplasmic reticulum lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0048238 NIF_Subcellular:sao927884761 SER lumen|smooth ER lumen The volume enclosed by the membranes of the smooth endoplasmic reticulum. CHEBI:87133 7-methyl-GTP(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87133 GO:0048237 rough endoplasmic reticulum lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0048237 NIF_Subcellular:sao1819509473 RER lumen|rough ER lumen The volume enclosed by the membranes of the rough endoplasmic reticulum. CHEBI:87136 trans-caffeoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87136 GO:0000295 adenine nucleotide transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000295 Reactome:R-HSA-389652 Enables the transfer of adenine nucleotides (AMP, ADP, and ATP) from one side of a membrane to the other. GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000294 nuclear mRNA catabolic process, endonucleolytic cleavage-dependent decay|mRNA catabolic process, endonucleolytic|mRNA catabolism, endonucleolytic|endonucleolytic mRNA decay|mRNA degradation, endonucleolytic cleavage-dependent decay|mRNA breakdown, endonucleolytic cleavage-dependent decay A minor degradation pathway nuclear-transcribed mRNAs that begins with an endonucleolytic cleavage to generate unprotected ends. GO:0048236 plant-type sporogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048236 plant spore formation The formation of plant spores derived from the products of meiosis. The spore gives rise to gametophytes. GO:0048235 pollen sperm cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048235 male gametophyte sperm cell differentiation|sperm cell differentiation|male gamete generation The process in which a relatively unspecialized cell acquires specialized features of a haploid sperm cell within the plant gametophyte. GO:0000293 ferric-chelate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000293 EC:1.16.1.7|RHEA:15061|MetaCyc:FERRIC-CHELATE-REDUCTASE-RXN NADH:Fe(3+) oxidoreductase activity|iron chelate reductase activity|NADH:Fe(3+)-EDTA reductase activity|NADH:Fe3+ oxidoreductase activity|ferric chelate reductase activity|NADH:Fe3+-EDTA reductase activity|NADH2:Fe3+ oxidoreductase activity|Fe(II):NAD+ oxidoreductase activity Catalysis of the reaction: 2 Fe2+ + NAD+ = 2 Fe3+ + NADH + H(+). GO:0000292 RNA fragment catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000292 RNA fragment breakdown|RNA fragment catabolism|group I intron catabolic process|RNA fragment degradation The chemical reactions and pathways resulting in the breakdown of a fragment of RNA, such as excised introns or sequences removed from ribosomal RNA during processing. GO:0048234 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048234 CHEBI:87137 dihydrocaffeoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87137 CHEBI:133585 epoxyoctadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133585 CHEBI:87139 3-oxochol-4-en-24-oyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87139 CHEBI:133586 epoxyoctadecenoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133586 GO:0000266 mitochondrial fission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000266 mitochondrial division|mitochondrial proliferation The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments. GO:0048244 phytanoyl-CoA dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048244 MetaCyc:1.14.11.18-RXN|KEGG_REACTION:R05722|Reactome:R-HSA-389639|EC:1.14.11.18|RHEA:16065 phytanoyl-CoA hydroxylase activity|phytanoyl-CoA 2-hydroxylase activity|phytanoyl-CoA 2 oxoglutarate dioxygenase activity|phytanoyl-CoA, 2-oxoglutarate:oxygen oxidoreductase (2-hydroxylating)|phytanoyl-CoA alpha-hydroxylase activity Catalysis of the reaction: 2-oxoglutarate + O(2) + phytanoyl-CoA = 2-hydroxyphytanoyl-CoA + CO(2) + succinate. CHEBI:63190 (+)-beta-caryophyllene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63190 GO:0048243 norepinephrine secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048243 noradrenaline secretion The regulated release of norepinephrine by a cell. Norepinephrine is a catecholamine and it acts as a hormone and as a neurotransmitter of most of the sympathetic nervous system. GO:0000265 obsolete heterotrimeric G-protein GTPase, gamma-subunit biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000265 heterotrimeric G-protein GTPase, gamma-subunit OBSOLETE. Smallest subunit of a heterotrimeric G-protein GTPase; associates tightly with the beta subunit. GO:0000264 obsolete heterotrimeric G-protein GTPase, beta-subunit biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000264 heterotrimeric G-protein GTPase, beta-subunit OBSOLETE. Subunit of a heterotrimeric G-protein GTPase; associates tightly with the gamma subunit. GO:0048242 epinephrine secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048242 adrenaline secretion The regulated release of epinephrine by a cell. Epinephrine is a catecholamine hormone secreted by the adrenal medulla and a neurotransmitter, released by certain neurons and active in the central nervous system. GO:0000263 obsolete heterotrimeric G-protein GTPase, alpha-subunit biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000263 heterotrimeric G-protein GTPase, alpha-subunit OBSOLETE. Subunit of a heterotrimeric G-protein GTPase that contains the guanine nucleotide binding site and possesses GTPase activity. GO:0048241 epinephrine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048241 adrenaline transport The directed movement of epinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:1903409 reactive oxygen species biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903409 ROS generation|reactive oxygen species biosynthesis|reactive oxygen species generation|reactive oxygen species anabolism|reactive oxygen species synthesis|reactive oxygen species formation|ROS formation The chemical reactions and pathways resulting in the formation of reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. GO:0048240 sperm capacitation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048240 sperm activation A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium. CHEBI:87161 dihydrobisanhydrobacterioruberin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87161 CHEBI:63194 D-ravidosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63194 CHEBI:38194 5alpha-hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38194 GO:1903408 positive regulation of sodium:potassium-exchanging ATPase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903408 upregulation of Na,K-pump|activation of Na+,K+ pump|up regulation of sodium/potassium-exchanging ATPase activity|upregulation of (Na+ + K+)-activated ATPase activity|upregulation of Na+,K+-ATPase activity|positive regulation of sodium/potassium-exchanging ATPase activity|up-regulation of sodium:potassium-exchanging ATPase activity|activation of sodium/potassium-exchanging ATPase activity|up regulation of sodium:potassium exchanging ATPase activity|activation of sodium:potassium exchanging ATPase activity|positive regulation of sodium:potassium exchanging ATPase activity|up-regulation of Na(+)/K(+)-exchanging ATPase activity|positive regulation of (Na+ + K+)-ATPase activity|up-regulation of Na+,K+ pump|up-regulation of Na+/K+-exchanging ATPase activity|positive regulation of Na,K-activated ATPase activity|upregulation of ATP phosphohydrolase (Na+/K+-exchanging)|up-regulation of Na+/K+-ATPase activity|up regulation of sodium/potassium-transporting ATPase activity|up-regulation of Na(+)/K(+)-ATPase activity|up regulation of (Na+ + K+)-ATPase activity|up regulation of Na,K-activated ATPase activity|activation of Na(+)/K(+)-ATPase activity|activation of Na+/K+-ATPase activity|up-regulation of (Na+ + K+)-activated ATPase activity|up regulation of Na,K-pump|activation of sodium/potassium-transporting ATPase activity|positive regulation of sodium/potassium-transporting ATPase activity|up-regulation of Na+,K+-ATPase activity|activation of (Na+ + K+)-activated ATPase activity|positive regulation of Na,K-pump|activation of Na+,K+-ATPase activity|upregulation of sodium:potassium-exchanging ATPase activity|up-regulation of sodium/potassium-exchanging ATPase activity|upregulation of Na+/K+-exchanging ATPase activity|upregulation of Na+,K+ pump|upregulation of Na(+)/K(+)-exchanging ATPase activity|up-regulation of sodium:potassium exchanging ATPase activity|up-regulation of ATP phosphohydrolase (Na+/K+-exchanging)|activation of Na,K-pump|upregulation of (Na+ + K+)-ATPase activity|activation of ATP phosphohydrolase (Na+/K+-exchanging)|positive regulation of Na+/K+-ATPase activity|upregulation of Na,K-activated ATPase activity|positive regulation of Na(+)/K(+)-ATPase activity|positive regulation of (Na+ + K+)-activated ATPase activity|up regulation of Na+/K+-ATPase activity|up-regulation of sodium/potassium-transporting ATPase activity|up regulation of Na(+)/K(+)-ATPase activity|positive regulation of Na+,K+-ATPase activity|up regulation of sodium:potassium-exchanging ATPase activity|up regulation of (Na+ + K+)-activated ATPase activity|upregulation of sodium/potassium-exchanging ATPase activity|up-regulation of Na,K-pump|activation of sodium:potassium-exchanging ATPase activity|up regulation of Na+,K+-ATPase activity|up regulation of Na+,K+ pump|upregulation of sodium:potassium exchanging ATPase activity|up regulation of Na(+)/K(+)-exchanging ATPase activity|up regulation of Na+/K+-exchanging ATPase activity|up-regulation of (Na+ + K+)-ATPase activity|activation of Na+/K+-exchanging ATPase activity|positive regulation of Na(+)/K(+)-exchanging ATPase activity|activation of Na(+)/K(+)-exchanging ATPase activity|positive regulation of Na+,K+ pump|positive regulation of Na+/K+-exchanging ATPase activity|activation of (Na+ + K+)-ATPase activity|up-regulation of Na,K-activated ATPase activity|positive regulation of ATP phosphohydrolase (Na+/K+-exchanging)|activation of Na,K-activated ATPase activity|upregulation of sodium/potassium-transporting ATPase activity|up regulation of ATP phosphohydrolase (Na+/K+-exchanging)|upregulation of Na+/K+-ATPase activity|upregulation of Na(+)/K(+)-ATPase activity Any process that activates or increases the frequency, rate or extent of sodium:potassium-exchanging ATPase activity. GO:0000269 toxin export channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000269 Enables the energy independent passage of toxins, sized less than 1000 Da, across a membrane towards the outside of the cell. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria. GO:1903407 negative regulation of sodium:potassium-exchanging ATPase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903407 down regulation of sodium/potassium-transporting ATPase activity|inhibition of Na+,K+-ATPase activity|downregulation of ATP phosphohydrolase (Na+/K+-exchanging)|negative regulation of (Na+ + K+)-ATPase activity|down-regulation of (Na+ + K+)-ATPase activity|down-regulation of Na,K-activated ATPase activity|down regulation of Na,K-pump|negative regulation of Na,K-activated ATPase activity|inhibition of sodium:potassium-exchanging ATPase activity|downregulation of sodium/potassium-transporting ATPase activity|down regulation of ATP phosphohydrolase (Na+/K+-exchanging)|inhibition of Na+/K+-exchanging ATPase activity|inhibition of Na(+)/K(+)-exchanging ATPase activity|downregulation of Na,K-pump|inhibition of ATP phosphohydrolase (Na+/K+-exchanging)|negative regulation of sodium/potassium-exchanging ATPase activity|down-regulation of sodium/potassium-exchanging ATPase activity|negative regulation of sodium:potassium exchanging ATPase activity|down-regulation of sodium:potassium exchanging ATPase activity|downregulation of (Na+ + K+)-ATPase activity|inhibition of Na+,K+ pump|downregulation of Na,K-activated ATPase activity|inhibition of sodium/potassium-exchanging ATPase activity|negative regulation of sodium/potassium-transporting ATPase activity|down-regulation of sodium/potassium-transporting ATPase activity|negative regulation of Na(+)/K(+)-ATPase activity|down-regulation of Na(+)/K(+)-ATPase activity|down-regulation of Na+/K+-ATPase activity|down regulation of sodium:potassium-exchanging ATPase activity|negative regulation of Na+/K+-ATPase activity|down regulation of (Na+ + K+)-ATPase activity|down regulation of Na,K-activated ATPase activity|down-regulation of Na,K-pump|inhibition of sodium:potassium exchanging ATPase activity|negative regulation of Na,K-pump|down-regulation of (Na+ + K+)-activated ATPase activity|negative regulation of (Na+ + K+)-activated ATPase activity|inhibition of (Na+ + K+)-ATPase activity|down regulation of Na+/K+-exchanging ATPase activity|negative regulation of Na+,K+-ATPase activity|down regulation of Na+,K+ pump|down regulation of Na(+)/K(+)-exchanging ATPase activity|down-regulation of Na+,K+-ATPase activity|inhibition of Na,K-activated ATPase activity|downregulation of sodium:potassium-exchanging ATPase activity|inhibition of sodium/potassium-transporting ATPase activity|downregulation of Na+/K+-exchanging ATPase activity|downregulation of Na+,K+ pump|downregulation of Na(+)/K(+)-exchanging ATPase activity|downregulation of Na+/K+-ATPase activity|down-regulation of ATP phosphohydrolase (Na+/K+-exchanging)|negative regulation of ATP phosphohydrolase (Na+/K+-exchanging)|downregulation of Na(+)/K(+)-ATPase activity|down regulation of sodium/potassium-exchanging ATPase activity|downregulation of (Na+ + K+)-activated ATPase activity|downregulation of Na+,K+-ATPase activity|down regulation of Na(+)/K(+)-ATPase activity|down regulation of Na+/K+-ATPase activity|inhibition of Na,K-pump|down regulation of sodium:potassium exchanging ATPase activity|down-regulation of sodium:potassium-exchanging ATPase activity|downregulation of sodium/potassium-exchanging ATPase activity|inhibition of Na+/K+-ATPase activity|inhibition of Na(+)/K(+)-ATPase activity|down regulation of (Na+ + K+)-activated ATPase activity|down-regulation of Na+/K+-exchanging ATPase activity|down-regulation of Na+,K+ pump|negative regulation of Na+,K+ pump|negative regulation of Na(+)/K(+)-exchanging ATPase activity|down-regulation of Na(+)/K(+)-exchanging ATPase activity|negative regulation of Na+/K+-exchanging ATPase activity|down regulation of Na+,K+-ATPase activity|inhibition of (Na+ + K+)-activated ATPase activity|downregulation of sodium:potassium exchanging ATPase activity Any process that stops, prevents or reduces the frequency, rate or extent of sodium:potassium-exchanging ATPase activity. CHEBI:87163 dihydroisopentenyldehydrorhodopin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87163 GO:0000268 peroxisome targeting sequence binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000268 peroxisome targeting signal receptor|PTS binding|PTS receptor Interacting selectively and non-covalently with a peroxisomal targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome. GO:0000267 obsolete cell fraction biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000267 cell fraction OBSOLETE. A generic term for parts of cells prepared by disruptive biochemical techniques. CHEBI:87162 isopentenyldehydrorhodopin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87162 CHEBI:63191 beta-caryophyllene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63191 GO:1903406 regulation of sodium:potassium-exchanging ATPase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903406 regulation of sodium/potassium-transporting ATPase activity|regulation of ATP phosphohydrolase (Na+/K+-exchanging)|regulation of Na,K-pump|regulation of (Na+ + K+)-ATPase activity|regulation of Na,K-activated ATPase activity|regulation of Na(+)/K(+)-exchanging ATPase activity|regulation of Na+/K+-exchanging ATPase activity|regulation of Na+,K+ pump|regulation of Na(+)/K(+)-ATPase activity|regulation of Na+/K+-ATPase activity|regulation of (Na+ + K+)-activated ATPase activity|regulation of sodium/potassium-exchanging ATPase activity|regulation of Na+,K+-ATPase activity|regulation of sodium:potassium exchanging ATPase activity|regulation of sodium pump Any process that modulates the frequency, rate or extent of sodium:potassium-exchanging ATPase activity. GO:1903405 protein localization to nuclear body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903405 protein localization in nuclear body|protein localisation to nuclear body|protein localisation in nuclear body A process in which a protein is transported to, or maintained in, a location within a nuclear body. CHEBI:87165 C50 carotenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87165 GO:1903404 positive regulation of renal phosphate excretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903404 upregulation of renal phosphate excretion|up regulation of renal phosphate ion excretion|activation of renal phosphate ion excretion|positive regulation of renal phosphate ion excretion|up regulation of renal phosphate excretion|activation of renal phosphate excretion|up-regulation of renal phosphate ion excretion|up-regulation of renal phosphate excretion|upregulation of renal phosphate ion excretion Any process that activates or increases the frequency, rate or extent of renal phosphate excretion. CHEBI:87164 6-hydroxy-N-methylmyosmine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87164 GO:1903403 negative regulation of renal phosphate excretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903403 downregulation of renal phosphate ion excretion|down regulation of renal phosphate excretion|downregulation of renal phosphate excretion|down-regulation of renal phosphate ion excretion|negative regulation of renal phosphate ion excretion|inhibition of renal phosphate ion excretion|down-regulation of renal phosphate excretion|inhibition of renal phosphate excretion|down regulation of renal phosphate ion excretion Any process that stops, prevents or reduces the frequency, rate or extent of renal phosphate excretion. CHEBI:87167 S-[(2E,6E)-farnesyl]-L-cysteine methyl ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87167 CHEBI:63196 (+)-caryolan-1-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63196 GO:0048249 high-affinity phosphate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048249 high affinity phosphate transmembrane transporter activity Enables the transfer of phosphate from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. GO:1903402 regulation of renal phosphate excretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903402 regulation of renal phosphate ion excretion Any process that modulates the frequency, rate or extent of renal phosphate excretion. GO:1903401 L-lysine transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903401 The directed movement of L-lysine across a membrane. CHEBI:87169 S-sulfo-L-cysteine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87169 GO:0000262 mitochondrial chromosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000262 NIF_Subcellular:sao1186327184 mtDNA|mitochondrial DNA|mitochondrial genome A chromosome found in the mitochondrion of a eukaryotic cell. GO:0048248 CXCR3 chemokine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048248 Interacting selectively and non-covalently with a the CXCR3 chemokine receptor. GO:1903400 L-arginine transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903400 The directed movement of L-arginine across a membrane. GO:0000261 obsolete sodium-translocating V-type ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000261 sodium-translocating V-type ATPase activity OBSOLETE. Catalysis of the reaction: ATP + H2O + Na+(in) = ADP + phosphate + Na+(out). Found in vacuoles of eukaryotes and in bacteria. GO:0048247 lymphocyte chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048247 The directed movement of a lymphocyte in response to an external stimulus. CHEBI:87168 C45 carotenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87168 GO:0000260 obsolete hydrogen-translocating V-type ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000260 hydrogen-translocating V-type ATPase activity OBSOLETE. Catalysis of the reaction: ATP + H2O + H(+)(in) = ADP + phosphate + H+(out). Found in vacuoles of eukaryotes and in bacteria. GO:0048246 macrophage chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048246 The movement of a macrophage in response to an external stimulus. GO:0048245 eosinophil chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048245 The movement of an eosinophil in response to an external stimulus. CHEBI:133556 oxooctadecadienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133556 CHEBI:133558 hydroperoxyoctadecatrienoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133558 CHEBI:133557 hydroperoxyoctadecenoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133557 CHEBI:38187 pyridinecarbaldehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38187 CHEBI:38186 isonicotinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38186 CHEBI:38184 picolinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38184 CHEBI:38189 pyridine N-oxides biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38189 CHEBI:38188 pyridinium salt biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38188 GO:0000277 [cytochrome c]-lysine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000277 RHEA:24312|MetaCyc:2.1.1.59-RXN|EC:2.1.1.59 cytochrome c-specific protein methylase III activity|cytochrome c methyltransferase activity|cytochrome c-specific protein-lysine methyltransferase activity|cytochrome c (lysine) methyltransferase activity|cytochrome c-lysine N-methyltransferase activity|S-adenosyl-L-methionine:cytochrome c-L-lysine 6-N-methyltransferase activity|S-adenosyl-L-methionine:cytochrome c-L-lysine N6-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + cytochrome c L-lysine = S-adenosyl-L-homocysteine + cytochrome c N6-methyl-L-lysine. This is the addition of a methyl group to the N6 atom of a lysine residue in cytochrome c. GO:0048255 mRNA stabilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048255 Prevention of degradation of mRNA molecules. In the absence of compensating changes in other processes, the slowing of mRNA degradation can result in an overall increase in the population of active mRNA molecules. GO:0048254 snoRNA localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048254 snoRNA localisation|small nucleolar RNA localization|establishment and maintenance of snoRNA localization Any process in which small nucleolar RNA is transported to, or maintained in, a specific location. GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000276 All non-F1 subunits of the mitochondrial hydrogen-transporting ATP synthase, including integral and peripheral mitochondrial inner membrane proteins. GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1) biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000275 hydrogen-transporting ATP synthase, F1 sector|proton-transporting ATP synthase complex, catalytic core F(1) The catalytic sector of the mitochondrial hydrogen-transporting ATP synthase; it comprises the catalytic core and central stalk, and is peripherally associated with the mitochondrial inner membrane when the entire ATP synthase is assembled. GO:0048253 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048253 GO:0000274 mitochondrial proton-transporting ATP synthase, stator stalk biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000274 mitochondrial proton-transporting ATP synthase, peripheral stalk One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the mitochondrial membrane-associated F0 proteins; is thought to prevent futile rotation of the catalytic core. GO:0048252 lauric acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048252 n-dodecanoic acid metabolic process|lauric acid metabolism|n-dodecanoic acid metabolism The chemical reactions and pathways involving lauric acid, a fatty acid with the formula CH3(CH2)10COOH. Derived from vegetable sources. GO:0048251 elastic fiber assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048251 elastin fiber assembly|elastin fibre assembly|elastic fibre assembly Assembly of the extracellular matrix fibers that enables the matrix to recoil after transient stretching. GO:1903419 protein localization to cortical endoplasmic reticulum biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903419 protein localisation in cortical endoplasmic reticulum|protein localization in cortical endoplasmic reticulum|protein localization to cortical ER|protein localisation to cortical endoplasmic reticulum A process in which a protein is transported to, or maintained in, a location within a cortical endoplasmic reticulum. GO:0048250 iron import into the mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048250 mitochondrial iron ion transport|mitochondrial iron transport|mitochondrial iron ion transmembrane transport|mitochondrial iron cation transmembrane transport The process in which iron is transported from the cytosol, into the mitochondrial matrix. GO:1903418 protein localization to plasma membrane of cell tip biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903418 protein localisation to plasma membrane of cell tip|protein localization in plasma membrane of cell tip|protein localisation in plasma membrane of cell tip A process in which a protein is transported to, or maintained in, a location within a plasma membrane of cell tip. GO:0000279 M phase biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0000279 Wikipedia:M_phase M-phase A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase. GO:0000278 mitotic cell cycle biolink:BiologicalProcess go-plus goslim_chembl|goslim_yeast|goslim_drosophila|goslim_generic http://purl.obolibrary.org/obo/GO_0000278 Wikipedia:Mitosis mitosis Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent. GO:1903416 response to glycoside biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903416 cellular response to ouabain Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoside stimulus. GO:1903415 flavonoid transport from endoplasmic reticulum to plant-type vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903415 flavonoid accumulation in vacuole The directed movement of flavonoid from endoplasmic reticulum to plant-type vacuole. GO:1903414 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1903414 GO:1903413 cellular response to bile acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903413 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus. GO:0048259 regulation of receptor-mediated endocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048259 regulation of receptor mediated endocytosis Any process that modulates the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport. GO:1903412 response to bile acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903412 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus. GO:0000273 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000273 GO:0000272 polysaccharide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000272 multicellular organismal polysaccharide catabolic process|polysaccharide degradation|polysaccharide breakdown|polysaccharide catabolism The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. GO:1903411 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1903411 GO:0048258 3-ketoglucose-reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048258 MetaCyc:KETOGLUCOSE-REDUCTASE-RXN Catalysis of the reaction: NADP+ + 3-dehydro-alpha-D-glucose = NADPH + alpha-D-glucose. GO:0000271 polysaccharide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000271 glycan biosynthesis|glycan biosynthetic process|polysaccharide anabolism|polysaccharide biosynthesis|polysaccharide synthesis|polysaccharide formation The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. GO:1903410 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1903410 GO:0048257 3'-flap endonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048257 3' flap endonuclease activity Catalysis of the cleavage of a 3' flap structure in DNA, but not other DNA structures; processes the 3' ends of Okazaki fragments in lagging strand DNA synthesis. GO:0048256 flap endonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048256 Catalysis of the cleavage of a flap structure in DNA, but not other DNA structures; processes the ends of Okazaki fragments in lagging strand DNA synthesis. GO:0000270 peptidoglycan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000270 peptidoglycan metabolism|murein metabolism|murein metabolic process The chemical reactions and pathways involving peptidoglycans, any of a class of glycoconjugates found only in bacterial cell walls and consisting of strands of glycosaminoglycan cross-linked by oligopeptides to form a huge and rigid network. CHEBI:38198 aminoalkylpyridine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38198 CHEBI:38197 furopyridine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38197 CHEBI:38196 hydroxymethylpyridine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38196 GO:0048266 behavioral response to pain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048266 behavioural response to pain Any process that results in a change in the behavior of an organism as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli. GO:0000244 spliceosomal tri-snRNP complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000244 spliceosomal tri-snRNP assembly|snRNP recycling|assembly of spliceosomal tri-snRNP U4atac/U6atac.U5|assembly of spliceosomal tri-snRNP U4/U6.U5|spliceosomal tri-snRNP U4/U6.U5 assembly|spliceosomal tri-snRNP U4atac/U6atac.U5 assembly|assembly of spliceosomal tri-snRNP The formation of a tri-snRNP complex containing U4 and U6 (or U4atac and U6atac) snRNAs and U5 snRNAs and associated proteins. This includes reannealing of U4 and U6 (or U4atac and U6atac) snRNAs released from previous rounds of splicing to reform the U4/U6 snRNP (or U4atac/U6atac snRNP) as well as the subsequent association of the U5 snRNP with the U4/U6 snRNP (or U4atac/U6atac snRNP) to form a tri-snRNP that is ready to reassemble into another spliceosome complex. GO:0000243 commitment complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000243 mammalian spliceosomal E complex|yeast spliceosomal complex CC|mammalian spliceosomal complex E A spliceosomal complex that is formed by association of the U1 snRNP with the 5' splice site of an unspliced intron in an RNA transcript. GO:0048265 response to pain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048265 physiological response to pain Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli. GO:0000242 pericentriolar material biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000242 A network of small fibers that surrounds the centrioles in cells; contains the microtubule nucleating activity of the centrosome. GO:0048264 determination of ventral identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048264 determination of abaxial identity The regionalization process that results in the determination of the identity of part of an organism or organ where those parts are of the type that occur in the ventral region. Identity is considered to be the aggregate of characteristics by which a structure is recognized. CHEBI:87181 (2R)-2,6-dimethylheptanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87181 GO:0000241 diakinesis biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0000241 Wikipedia:Meiosis#Diakinesis|Wikipedia:Diakinesis The cell cycle phase which follows diplotene during prophase I of meiosis, the separation of homologous chromosomes is complete and crossing over has occurred. GO:0048263 determination of dorsal identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048263 determination of adaxial identity Determination of the identity of part of an organism or organ where those parts are of the type that occur in the dorsal region. Identity is considered to be the aggregate of characteristics by which a structure is recognized. CHEBI:38172 monohydroxy-1,3,5-triazine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38172 GO:0048262 determination of dorsal/ventral asymmetry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048262 determination of dorsal-ventral asymmetry|determination of dorsoventral asymmetry|determination of adaxial/abaxial asymmetry Determination of asymmetry from the dorsal to the ventral side; as, the dorsoventral axis. GO:0000248 C-5 sterol desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000248 Reactome:R-HSA-6807053|Reactome:R-HSA-195664 sterol-C5-desaturase activity Catalysis of the reaction: 5,7,24(28)-ergostatrienol + O2 + NADPH = 5,7,22,24(28)-ergostatetraenol + 2 H2O + NADP+. GO:0048261 negative regulation of receptor-mediated endocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048261 down regulation of receptor mediated endocytosis|downregulation of receptor mediated endocytosis|down-regulation of receptor mediated endocytosis|negative regulation of receptor mediated endocytosis|inhibition of receptor mediated endocytosis Any process that stops, prevents, or reduces the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport. GO:0000247 C-8 sterol isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000247 delta-8-delta-7 sterol isomerase activity Catalysis of the reaction which results in unsaturation at C-7 in the B ring of sterols. CHEBI:87182 (2S)-2,6-dimethylheptanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87182 GO:1903429 regulation of cell maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903429 regulation of functional differentiation Any process that modulates the frequency, rate or extent of cell maturation. GO:0048260 positive regulation of receptor-mediated endocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048260 positive regulation of receptor mediated endocytosis|up regulation of receptor mediated endocytosis|activation of receptor mediated endocytosis|stimulation of receptor mediated endocytosis|up-regulation of receptor mediated endocytosis|upregulation of receptor mediated endocytosis Any process that activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport. GO:0000246 delta24(24-1) sterol reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000246 KEGG_REACTION:R05641|RHEA:18501|MetaCyc:1.3.1.71-RXN|EC:1.3.1.71 sterol delta-24(28) reductase activity|ergosterol:NADP+ delta24(241)-oxidoreductase activity|sterol delta24(28)-methylene reductase activity|delta24(241)-sterol reductase activity|sterol delta24(28)-reductase activity|sterol Delta(24(28))-methylene reductase activity|D24(24-1)-sterol reductase activity|sterol Delta(24(28))-reductase activity|C-24(28) sterol reductase activity|sterol delta-24(28) methylene reductase activity Catalysis of the reaction: ergosterol + NADP(+) = ergosta-5,7,22,24(24(1))-tetraen-3beta-ol + H(+) + NADPH. CHEBI:38170 diamino-1,3,5-triazine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38170 GO:1903428 positive regulation of reactive oxygen species biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903428 upregulation of ROS generation|up regulation of ROS formation|positive regulation of reactive oxygen species generation|upregulation of reactive oxygen species synthesis|up regulation of reactive oxygen species generation|positive regulation of ROS formation|upregulation of reactive oxygen species formation|up regulation of reactive oxygen species anabolism|activation of ROS formation|positive regulation of reactive oxygen species biosynthesis|up-regulation of ROS generation|positive regulation of reactive oxygen species anabolism|activation of reactive oxygen species anabolism|up regulation of reactive oxygen species biosynthesis|up regulation of reactive oxygen species biosynthetic process|up regulation of reactive oxygen species synthesis|upregulation of reactive oxygen species generation|positive regulation of reactive oxygen species synthesis|up-regulation of ROS formation|activation of reactive oxygen species synthesis|activation of ROS generation|up regulation of reactive oxygen species formation|positive regulation of reactive oxygen species formation|activation of reactive oxygen species formation|positive regulation of ROS generation|upregulation of reactive oxygen species biosynthetic process|upregulation of reactive oxygen species biosynthesis|up-regulation of reactive oxygen species anabolism|up-regulation of reactive oxygen species generation|up regulation of ROS generation|upregulation of ROS formation|up-regulation of reactive oxygen species synthesis|up-regulation of reactive oxygen species formation|activation of reactive oxygen species generation|up-regulation of reactive oxygen species biosynthetic process|up-regulation of reactive oxygen species biosynthesis|upregulation of reactive oxygen species anabolism|activation of reactive oxygen species biosynthetic process|activation of reactive oxygen species biosynthesis Any process that activates or increases the frequency, rate or extent of reactive oxygen species biosynthetic process. GO:0000245 spliceosomal complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000245 spliceosome assembly The aggregation, arrangement and bonding together of a spliceosomal complex, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions. GO:1903427 negative regulation of reactive oxygen species biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903427 prevention of ROS generation|down regulation of reactive oxygen species anabolism|down-regulation of reactive oxygen species biosynthetic process|down-regulation of reactive oxygen species biosynthesis|inhibition of ROS generation|negative regulation of reactive oxygen species biosynthesis|down regulation of reactive oxygen species synthesis|downregulation of reactive oxygen species anabolism|downregulation of reactive oxygen species generation|down-regulation of ROS formation|negative regulation of ROS formation|down regulation of reactive oxygen species formation|downregulation of reactive oxygen species synthesis|down regulation of reactive oxygen species generation|downregulation of reactive oxygen species formation|downregulation of reactive oxygen species biosynthesis|downregulation of reactive oxygen species biosynthetic process|down-regulation of reactive oxygen species anabolism|negative regulation of reactive oxygen species anabolism|negative regulation of ROS generation|down-regulation of ROS generation|down regulation of reactive oxygen species biosynthesis|down regulation of reactive oxygen species biosynthetic process|inhibition of reactive oxygen species generation|down-regulation of reactive oxygen species synthesis|negative regulation of reactive oxygen species synthesis|inhibition of reactive oxygen species biosynthetic process|inhibition of reactive oxygen species biosynthesis|inhibition of ROS formation|inhibition of reactive oxygen species anabolism|down-regulation of reactive oxygen species formation|negative regulation of reactive oxygen species formation|inhibition of reactive oxygen species synthesis|downregulation of ROS generation|down regulation of ROS formation|inhibition of reactive oxygen species formation|negative regulation of reactive oxygen species generation|down-regulation of reactive oxygen species generation|down regulation of ROS generation|downregulation of ROS formation Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species biosynthetic process. CHEBI:133538 L-lysine zwitterion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133538 GO:1903426 regulation of reactive oxygen species biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903426 regulation of reactive oxygen species anabolism|regulation of reactive oxygen species synthesis|regulation of reactive oxygen species generation|regulation of reactive oxygen species formation|regulation of reactive oxygen species biosynthesis|regulation of ROS generation|regulation of ROS formation Any process that modulates the frequency, rate or extent of reactive oxygen species biosynthetic process. GO:1903425 fluoride transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1903425 Enables the transfer of fluoride from one side of a membrane to the other. GO:1903424 fluoride transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903424 transmembrane fluoride transport|fluoride membrane transport The process in which fluoride is transported across a membrane. CHEBI:133539 hydroxyicosatrienoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133539 GO:0000240 diplotene biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0000240 Wikipedia:Diplotene|Wikipedia:Meiosis#Diplotene The cell cycle phase which follows pachytene during prophase I of meiosis, during which the homologous chromosomes begin to separate and the synaptonemal complex dissolves. GO:1903423 positive regulation of synaptic vesicle recycling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903423 up regulation of kiss-and-run synaptic vesicle recycling|activation of kiss-and-stay synaptic vesicle recycling|positive regulation of kiss-and-run synaptic vesicle recycling|activation of synaptic vesicle recycling|up-regulation of synaptic vesicle recycling|positive regulation of kiss-and-stay synaptic vesicle recycling|activation of kiss-and-run synaptic vesicle recycling|up regulation of kiss-and-stay synaptic vesicle recycling|up-regulation of kiss-and-run synaptic vesicle recycling|up regulation of synaptic vesicle recycling|upregulation of kiss-and-stay synaptic vesicle recycling|upregulation of kiss-and-run synaptic vesicle recycling|upregulation of synaptic vesicle recycling|up-regulation of kiss-and-stay synaptic vesicle recycling Any process that activates or increases the frequency, rate or extent of synaptic vesicle recycling. GO:1903422 negative regulation of synaptic vesicle recycling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903422 downregulation of kiss-and-run synaptic vesicle recycling|negative regulation of kiss-and-stay synaptic vesicle recycling|down-regulation of kiss-and-stay synaptic vesicle recycling|negative regulation of kiss-and-run synaptic vesicle recycling|down-regulation of kiss-and-run synaptic vesicle recycling|down-regulation of synaptic vesicle recycling|downregulation of kiss-and-stay synaptic vesicle recycling|down regulation of kiss-and-stay synaptic vesicle recycling|downregulation of synaptic vesicle recycling|inhibition of kiss-and-run synaptic vesicle recycling|down regulation of synaptic vesicle recycling|inhibition of kiss-and-stay synaptic vesicle recycling|inhibition of synaptic vesicle recycling|down regulation of kiss-and-run synaptic vesicle recycling Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle recycling. GO:0048269 methionine adenosyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0048269 MAT complex A multimeric enzyme complex composed of variable numbers of catalytic alpha subunits, and noncatalytic beta subunits. The beta subunits are believed to have a regulatory function. The enzyme complex catalyzes the synthesis of S-adenosylmethionine (AdoMet), which is the major methyl group donor, participating in the methylation of proteins, DNA, RNA, phospholipids, and other small molecules. GO:0048268 clathrin coat assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048268 clathrin cage assembly The process that results in the assembly of clathrin triskelia into the ordered structure known as a clathrin cage. GO:1903421 regulation of synaptic vesicle recycling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903421 regulation of kiss-and-stay synaptic vesicle recycling|regulation of kiss-and-run synaptic vesicle recycling Any process that modulates the frequency, rate or extent of synaptic vesicle recycling. GO:1903420 protein localization to endoplasmic reticulum tubular network biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903420 protein localisation to endoplasmic reticulum tubular network|protein localization in endoplasmic reticulum tubular network|protein localization to tubular ER|protein localisation in endoplasmic reticulum tubular network A process in which a protein is transported to, or maintained in, a location within an endoplasmic reticulum tubular network. GO:0048267 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048267 GO:1903430 negative regulation of cell maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903430 down regulation of functional differentiation|inhibition of cell maturation|inhibition of functional differentiation|down regulation of cell maturation|down-regulation of functional differentiation|negative regulation of functional differentiation|downregulation of cell maturation|downregulation of functional differentiation|down-regulation of cell maturation Any process that stops, prevents or reduces the frequency, rate or extent of cell maturation. GO:0014885 detection of injury involved in regulation of muscle adaptation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014885 detection of injury involved in regulation of muscle plasticity The series of events by which an injury stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation. GO:0014884 detection of muscle inactivity involved in regulation of muscle adaptation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014884 The series of events in which a muscle inactivity stimulus is received by a cell and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation. GO:0014883 transition between fast and slow fiber biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014883 transition fast-slow fibre|transition fast-slow fiber|transition between fast and slow fibre The process of conversion of fast-contracting muscle fibers to a slower character. This may involve slowing of contractile rate, slow myosin gene induction, increase in oxidative metabolic properties, altered electrophysiology and altered innervation. This process also regulates skeletal muscle adapatation. GO:0014882 regulation of myofibril number biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014882 change of myofibril number Any process that modulates the number of myofibrils. A myofibril is the contractile element of skeletal and cardiac muscle. It is a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism. NCBITaxon:2058185 Dictyosteliaceae organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_2058185 GO:0014889 muscle atrophy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014889 Wikipedia:Muscle_atrophy A process, occurring in the muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse. GO:0014888 striated muscle adaptation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014888 striated muscle plasticity Any process in which striated muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities. GO:0014887 cardiac muscle adaptation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014887 cardiac muscle plasticity The process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. GO:0014886 transition between slow and fast fiber biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014886 transition between slow and fast fibre|transition slow-fast fibre|transition slow-fast fiber The process of conversion of slow-contracting muscle fibers to a faster character. This may involve increasing of contractile rate, fast myosin gene induction, increase in glycolytic metabolic properties, altered electrophysiology and altered innervation. This process also regulates skeletal muscle adapatation. CHEBI:38165 organic heterooctacyclic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38165 CHEBI:38164 organic heteropentacyclic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38164 CHEBI:38163 organic heterotetracyclic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38163 GO:0000249 C-22 sterol desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000249 Catalysis of the formation of the C-22(23) double bond in the sterol side chain. An example reaction: 5,7,24(28)-ergostatrienol + O2 + NADPH = 5,7,22,24(28)-ergostatetraenol + 2 H2O + NADP+. CHEBI:38169 monoamino-1,3,5-triazine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38169 GO:0014881 regulation of myofibril size biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014881 change of myofibril size Any process that modulates the size of myofibrils. A myofibril is the contractile element of skeletal and cardiac muscle. It is a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism. GO:0014880 regulation of muscle filament sliding involved in regulation of the velocity of shortening in skeletal muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014880 Any process that modulates the frequency, rate or extent of muscle filament sliding, and consequently contributes to the regulation of the velocity of shortening of skeletal muscle contraction. CHEBI:38168 chloro-1,3,5-triazine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38168 CHEBI:38166 organic heteropolycyclic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38166 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097200 executioner caspase activity|effector caspase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the execution phase of apoptosis. GO:0048277 obsolete nonexocytotic vesicle docking biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048277 non-exocytotic vesicle docking|nonexocytotic vesicle docking OBSOLETE. The initial attachment of a transport vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane, during a non-exocytotic process. GO:0000255 allantoin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000255 allantoin metabolism The chemical reactions and pathways involving allantoin, (2,5-dioxo-4-imidazolidinyl)urea, an intermediate or end product of purine catabolism. GO:0000254 C-4 methylsterol oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000254 Reactome:R-HSA-194641|RHEA:55220|MetaCyc:1.14.13.72-RXN|EC:1.14.18.9|Reactome:R-HSA-194669 methylsterol monooxygenase activity|4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,NAD(P)H:oxygen oxidoreductase (hydroxylating)|methylsterol hydroxylase activity|4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,hydrogen-donor:oxygen oxidoreductase (hydroxylating)|4-methylsterol oxidase activity Catalysis of the reaction: 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol + NAD(P)H + H(+) + O2 = 4-beta-hydroxymethyl-4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-beta-ol + NAD(P)+ + H2O. GO:0048276 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048276 GO:0097202 activation of cysteine-type endopeptidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097202 activation of caspase activity|activation of metacaspase activity Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase. GO:0000253 3-keto sterol reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000253 RHEA:18409|MetaCyc:RXN66-319|Reactome:R-HSA-194689|MetaCyc:RXN66-19|MetaCyc:RXN66-314|MetaCyc:1.1.1.270-RXN|Reactome:R-HSA-194632|MetaCyc:RXN66-24|EC:1.1.1.270|MetaCyc:RXN3O-4110 3-KSR activity|3-keto-steroid reductase activity|3beta-hydroxy-steroid:NADP+ 3-oxidoreductase Catalysis of the reaction: a 3-beta-hydroxyl sterol + NADP+ = a 3-keto sterol + NADPH + H(+). CHEBI:87170 2-thiouridine 5'-phosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87170 GO:0048275 N-terminal peptidyl-arginine acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048275 RESID:AA0354 The acetylation of the N-terminal arginine of proteins; catalyzed by an uncharacterized arginyl-peptide alpha-N-acetyltransferase. GO:0000252 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000252 Reactome:R-HSA-194642|Reactome:R-HSA-194718|EC:1.1.1.170 C-3 sterol dehydrogenase (C-4 decarboxylase) activity|3beta-hydroxy-4beta-methylcholestenoate dehydrogenase activity|C-3 sterol dehydrogenase activity|sterol 4alpha-carboxylic decarboxylase activity|3beta-hydroxy-4alpha-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating)|sterol-4alpha-carboxylate 3-dehydrogenase (decarboxylating)|3beta-hydroxy-4beta-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating)|3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate:NAD(P)+ 3-oxidoreductase (decarboxylating)|sterol-4-carboxylate 3-dehydrogenase (decarboxylating) activity Catalysis of the reaction: 3-beta-hydroxy-4-beta-methyl-5-alpha-cholesta-8,24-dien-4-alpha-carboxylate + NAD(P)+ = 4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-one + CO2 + NAD(P)H. GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097201 Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). GO:0048274 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048274 GO:0048273 mitogen-activated protein kinase p38 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048273 MAPK p38 binding Interacting selectively and non-covalently with mitogen-activated protein kinase p38, an enzyme that catalyzes the transfer of phosphate from ATP to hydroxyl side chains on proteins in response to mitogen activation. GO:0000259 obsolete intracellular nucleoside transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000259 intracellular nucleoside transmembrane transporter activity OBSOLETE. Enables the directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose (a deoxyribonucleotide) within a cell. CHEBI:87172 5-taurinomethyluridine 5'-phosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87172 CHEBI:38183 pyridone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38183 CHEBI:87171 5-taurinomethyl-2-thiouridine 5'-phosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87171 GO:0000258 obsolete isoleucine/valine:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000258 isoleucine/valine:sodium symporter activity OBSOLETE. Catalysis of the reaction: (isoleucine or valine)(out) + Na+(out) = (isoleucine or valine)(in) + Na+(in). GO:0048272 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048272 CHEBI:38182 monohydroxypyridine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38182 GO:0000257 nitrilase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000257 UM-BBD_enzymeID:e0283|RHEA:21724|MetaCyc:3.5.5.1-RXN|KEGG_REACTION:R00540|EC:3.5.5.1 nitrile aminohydrolase activity|benzonitrilase activity|acetonitrilase activity Catalysis of the reaction: a nitrile + H2O = a carboxylate + NH3. Acts on a wide range of aromatic nitriles including (indole-3-yl)-acetonitrile and some aliphatic nitriles, and on the corresponding acid amides. GO:0048271 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048271 CHEBI:38181 pyridinemonocarboxylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38181 CHEBI:87173 (2R)-2-methyltetradecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87173 GO:1903439 calcitonin family receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1903439 A protein complex which is capable of calcitonin family receptor activity. Calcitonin family receptors may form dimers, trimers or tetramers; adrenomedullin and amylin receptors have only been observed as dimers so far. GO:0048270 methionine adenosyltransferase regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048270 MAT regulator activity Modulates the activity of methionine adenosyltransferase. GO:0000256 allantoin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000256 allantoin degradation|allantoin breakdown|allantoin catabolism The chemical reactions and pathways resulting in the breakdown of allantoin, (2,5-dioxo-4-imidazolidinyl)urea. CHEBI:38180 polycyclic heteroarene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38180 CHEBI:133549 N-acetyl-L-threoninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133549 GO:1903438 positive regulation of mitotic cytokinetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903438 up regulation of mitotic cytokinetic process|activation of mitotic cytokinetic process|up-regulation of mitotic cytokinetic process|upregulation of mitotic cytokinetic process Any process that activates or increases the frequency, rate or extent of mitotic cytokinetic process. GO:1903437 negative regulation of mitotic cytokinetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903437 downregulation of mitotic cytokinetic process|down-regulation of mitotic cytokinetic process|inhibition of mitotic cytokinetic process|down regulation of mitotic cytokinetic process Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cytokinetic process. GO:1903436 regulation of mitotic cytokinetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903436 Any process that modulates the frequency, rate or extent of mitotic cytokinetic process. GO:1903435 positive regulation of constitutive secretory pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903435 up regulation of constitutive secretory pathway|upregulation of constitutive secretory pathway|up-regulation of constitutive secretory pathway|activation of constitutive secretory pathway Any process that activates or increases the frequency, rate or extent of constitutive secretory pathway. GO:1903434 negative regulation of constitutive secretory pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903434 downregulation of constitutive secretory pathway|down regulation of constitutive secretory pathway|inhibition of constitutive secretory pathway|down-regulation of constitutive secretory pathway Any process that stops, prevents or reduces the frequency, rate or extent of constitutive secretory pathway. GO:0000251 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000251 GO:1903433 regulation of constitutive secretory pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903433 Any process that modulates the frequency, rate or extent of constitutive secretory pathway. GO:0000250 lanosterol synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000250 MetaCyc:LANOSTEROL-SYNTHASE-RXN|RHEA:14621|KEGG_REACTION:R03199|Reactome:R-HSA-191366|EC:5.4.99.7 2,3-oxidosqualene-lanosterol cyclase activity|oxidosqualene-lanosterol cyclase activity|squalene 2,3-epoxide:lanosterol cyclase activity|oxidosqualene:lanosterol cyclase activity|2,3-oxidosqualene sterol cyclase activity|oxidosqualene--lanosterol cyclase activity|2,3-epoxysqualene--lanosterol cyclase activity|OSC|lanosterol 2,3-oxidosqualene cyclase activity|squalene-2,3-oxide-lanosterol cyclase activity|2,3-epoxysqualene lanosterol cyclase activity|squalene epoxidase-cyclase activity|(S)-2,3-epoxysqualene mutase (cyclizing, lanosterol-forming)|2,3-epoxysqualene-lanosterol cyclase activity Catalysis of the reaction: (S)-2,3-epoxysqualene = lanosterol. This is a cyclization reaction that forms the sterol nucleus. GO:0048279 vesicle fusion with endoplasmic reticulum biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048279 vesicle fusion with ER The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the endoplasmic reticulum. GO:1903432 regulation of TORC1 signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903432 regulation of TORC1 signal transduction Any process that modulates the frequency, rate or extent of TORC1 signaling. GO:1903431 positive regulation of cell maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903431 upregulation of functional differentiation|up-regulation of cell maturation|upregulation of cell maturation|up-regulation of functional differentiation|activation of functional differentiation|up regulation of cell maturation|positive regulation of functional differentiation|activation of cell maturation|up regulation of functional differentiation Any process that activates or increases the frequency, rate or extent of cell maturation. GO:0048278 vesicle docking biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048278 vesicle to membrane docking The initial attachment of a transport vesicle membrane to the target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane. Docking requires only that the two membranes come close enough for these proteins to interact and adhere. GO:0014896 muscle hypertrophy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014896 Wikipedia:Muscle_hypertrophy The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy. GO:1903441 protein localization to ciliary membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903441 protein localization in ciliary membrane|protein localisation to ciliary membrane|protein localisation in ciliary membrane A process in which a protein is transported to, or maintained in, a location within a ciliary membrane. GO:1903440 amylin receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1903440 A protein complex which is capable of amylin receptor activity. GO:0014895 smooth muscle hypertrophy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014895 The enlargement or overgrowth of all or part of an organ due to an increase in size of its smooth muscle cells without cell division. Physiological hypertrophy is a normal process during development, and can also occur in mature structures on demand. In the uterus, smooth muscle cells undergo hypertrophy during pregnancy. GO:0014894 response to denervation involved in regulation of muscle adaptation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014894 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a denervation stimulus. This process occurs as part of the regulation of muscle adaptation. GO:0014893 response to rest involved in regulation of muscle adaptation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014893 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rest stimulus. This process occurs as part of the regulation of muscle adaptation. GO:0014899 cardiac muscle atrophy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014899 A process, occurring in the heart, in which a decrease in cell mass and then in heart size occurs due to shrinking of the individual cells. The shrinkage is caused by protein degradation. GO:0014898 cardiac muscle hypertrophy in response to stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014898 The physiological enlargement or overgrowth of all or part of the heart muscle due to an increase in size (not length) of individual cardiac muscle fibers, without cell division, as a result of a disturbance in organismal or cellular homeostasis. GO:0014897 striated muscle hypertrophy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014897 The enlargement or overgrowth of all or part of an organ due to an increase in size of muscle cells without cell division. In the case of striated muscle, this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils. GO:0097208 alveolar lamellar body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097208 A specialized secretory organelle found in type II pneumocytes and involved in the synthesis, secretion, and reutilization of pulmonary surfactant. GO:0048280 vesicle fusion with Golgi apparatus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048280 The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi. GO:0097207 bud dormancy process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097207 bud dormancy A dormancy process in which dormancy (sometimes called a dormant state) is induced, maintained or broken in a bud. Bud dormancy is a suspension of most physiological activity and growth that can be reactivated. It may be a response to environmental conditions such as seasonality or extreme heat, drought, or cold. The exit from bud dormancy is marked by the resumed growth of the bud. CHEBI:38175 triamino-1,3,5-triazine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38175 CHEBI:53794 (4-hydroxy-3-nitrophenyl)acetate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53794 CHEBI:38173 dihydroxy-1,3,5-triazine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38173 GO:0097209 epidermal lamellar body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097209 A specialized secretory organelle found in keratinocytes and involved in the formation of an impermeable, lipid-containing membrane that serves as a water barrier and is required for correct skin barrier function. GO:0097204 phagocytic cup base biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097204 The older part of the phagocytic cup where the actin cytoskeleton disassembles, allowing early incoming and outgoing vesicular trafficking. GO:0097203 phagocytic cup lip biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097203 The tip or margin of the progressing circular lamella that engulfs a particle during phagocytosis. When the two lips of the cup fuse it is converted into a phagosome. CHEBI:38179 monocyclic heteroarene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38179 GO:0014891 striated muscle atrophy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014891 A process, occurring in striated muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse. GO:0097206 nephrocyte filtration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097206 The process by which hemolymph is filtered based on size and charge through a nephrocyte filtration barrier formed by the basement membrane and nephrocyte diaphragm. GO:0014890 smooth muscle atrophy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014890 A process, occurring in smooth muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse. GO:0097205 renal filtration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097205 A renal system process in which fluid circulating through the body is filtered through a barrier system. GO:0000222 plasma membrane proton-transporting V-type ATPase, V0 domain biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000222 plasma membrane hydrogen ion-transporting ATPase V0 domain The V0 domain of a proton-transporting V-type ATPase found in the plasma membrane. GO:0048288 nuclear membrane fusion involved in karyogamy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048288 nuclear membrane fusion during karyogamy The joining of 2 or more lipid bilayer membranes that surround the nucleus during the creation of a single nucleus from multiple nuclei. GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000221 vacuolar hydrogen ion-transporting ATPase V1 domain The V1 domain of a proton-transporting V-type ATPase found in the vacuolar membrane. GO:0048287 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048287 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000220 vacuolar hydrogen ion-transporting ATPase V0 domain The V0 domain of a proton-transporting V-type ATPase found in the vacuolar membrane. GO:0048286 lung alveolus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048286 alveolarization|alveologenesis The process whose specific outcome is the progression of the alveolus over time, from its formation to the mature structure. The alveolus is a sac for holding air in the lungs; formed by the terminal dilation of air passageways. GO:0048285 organelle fission biolink:BiologicalProcess go-plus goslim_yeast|goslim_pir http://purl.obolibrary.org/obo/GO_0048285 The creation of two or more organelles by division of one organelle. GO:0000226 microtubule cytoskeleton organization biolink:BiologicalProcess go-plus goslim_drosophila|goslim_pombe http://purl.obolibrary.org/obo/GO_0000226 microtubule dynamics|microtubule cytoskeleton organisation|microtubule cytoskeleton organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. GO:0048284 organelle fusion biolink:BiologicalProcess go-plus goslim_yeast|goslim_pir http://purl.obolibrary.org/obo/GO_0048284 The creation of a single organelle from two or more organelles. CHEBI:38150 enterobactin(6-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38150 GO:0000225 N-acetylglucosaminylphosphatidylinositol deacetylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000225 RHEA:11660|MetaCyc:3.1.1.69-RXN|EC:3.5.1.89|Reactome:R-HSA-162857 N-acetylglucosaminylphosphatidylinositol de-N-acetylase activity|GlcNAc-PI deacetylase activity|N-acetyl-D-glucosaminylphosphatidylinositol acetylhydrolase activity|GlcNAc-PI de-N-acetylase activity|acetylglucosaminylphosphatidylinositol deacetylase activity|6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol acetylhydrolase activity Catalysis of the reaction: N-acetyl-D-glucosaminylphosphatidylinositol + H2O = D-glucosaminylphosphatidylinositol + acetate. This reaction is the second step of the biosynthesis of glycosylphosphatidylinositol (GPI), used to anchor various eukaryotic proteins to the cell-surface membrane. GO:0048283 indeterminate inflorescence morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048283 The process in which the anatomical structures of determinate inflorescences are generated and organized. A determinate inflorescence is one that can produce an undefined number of floral meristems. GO:0000224 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000224 EC:3.5.1.52|Reactome:R-HSA-8850594|MetaCyc:3.5.1.52-RXN glycopeptidase activity|N-linked-glycopeptide-(N-acetyl-beta-D-glucosaminyl)-L-asparagine amidohydrolase activity|PNGase|peptide:N-glycanase|N-oligosaccharide glycopeptidase activity|N-glycanase activity|glycopeptide N-glycosidase activity|PNGase F|jack-bean glycopeptidase|PNGase A Catalysis of the reaction: 4-N-(N-acetyl-D-glucosaminyl)-protein + H2O = N-acetyl-beta-D-glucosaminylamine + peptide L-aspartate. This reaction is the hydrolysis of an N4-(acetyl-beta-D-glucosaminyl)asparagine residue in which the N-acetyl-D-glucosamine residue may be further glycosylated, to yield a (substituted) N-acetyl-beta-D-glucosaminylamine and the peptide containing an aspartic residue. GO:0048282 determinate inflorescence morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048282 The process in which the anatomical structures of determinate inflorescences are generated and organized. A determinate inflorescence is one that can only produce a predetermined number of floral meristems. GO:0000223 plasma membrane proton-transporting V-type ATPase, V1 domain biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000223 plasma membrane hydrogen ion-transporting ATPase V1 domain The V1 domain of a proton-transporting V-type ATPase found in the plasma membrane. GO:0048281 inflorescence morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048281 The process in which the anatomical structures of inflorescences are generated and organized. An inflorescence is the part of a seed plant body that is usually above ground and that can bear flowers. GO:1903449 androst-4-ene-3,17-dione biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903449 androst-4-ene-3,17-dione synthesis|androst-4-ene-3,17-dione formation|androstenedione biosynthetic process|androst-4-ene-3,17-dione biosynthesis|androst-4-ene-3,17-dione anabolism The chemical reactions and pathways resulting in the formation of androst-4-ene-3,17-dione. GO:1903448 geraniol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903448 geraniol biosynthesis|geraniol anabolism|geraniol synthesis|geraniol formation The chemical reactions and pathways resulting in the formation of geraniol. GO:0014869 detection of muscle inactivity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014869 The series of events in which a muscle inactivity stimulus is received by a cell and converted into a molecular signal. GO:1903447 geraniol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903447 geraniol breakdown|geraniol degradation|geraniol catabolism The chemical reactions and pathways resulting in the breakdown of geraniol. CHEBI:133518 (E)-3-methylglutaconate anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133518 GO:1903446 geraniol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903446 geraniol metabolism The chemical reactions and pathways involving geraniol. CHEBI:133517 5alpha-androstane-3alpha,17beta-diol 17-glucosiduronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133517 GO:0014868 cross bridge cycling involved in regulation of the velocity of shortening in skeletal muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014868 A process in which cross bridges are broken and reformed during filament sliding as part of the regulation of the velocity of shortening in skeletal muscle contraction. GO:1903445 protein transport from ciliary membrane to plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903445 The directed movement of protein from ciliary membrane to plasma membrane. GO:1903444 negative regulation of brown fat cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903444 down-regulation of brown adipocyte cell differentiation|negative regulation of brown adipocyte cell differentiation|inhibition of brown adipocyte differentiation|downregulation of brown adipocyte cell differentiation|down regulation of brown adipocyte cell differentiation|down regulation of brown adipocyte differentiation|down-regulation of brown fat cell differentiation|inhibition of brown adipocyte cell differentiation|downregulation of brown adipocyte differentiation|downregulation of brown fat cell differentiation|negative regulation of brown adipocyte differentiation|down-regulation of brown adipocyte differentiation|down regulation of brown fat cell differentiation|inhibition of brown fat cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of brown fat cell differentiation. CHEBI:133519 5alpha-androstane-3alpha,17beta-diol 17-glucosiduronate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133519 GO:1903443 cellular response to lipoic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903443 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoic acid stimulus. GO:1903442 response to lipoic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903442 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoic acid stimulus. GO:0048289 isotype switching to IgE isotypes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048289 class switching to IgE isotypes|class switch recombination to IgE isotypes|isotype switch recombination to IgE isotypes The switching of activated B cells from IgM biosynthesis to IgE biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgE constant region gene segments in the immunoglobulin heavy chain locus. GO:1903452 positive regulation of G1 to G0 transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903452 positive regulation of cell cycle quiescence|positive regulation of establishment of cell quiescence|up regulation of establishment of cell quiescence|activation of cell cycle quiescence|upregulation of G1 to G0 transition|up-regulation of stationary phase|activation of G1/G0 transition|up-regulation of G1/G0 transition|up-regulation of cell cycle quiescence|activation of stationary phase|upregulation of establishment of cell quiescence|up regulation of G1 to G0 transition|positive regulation of stationary phase|activation of G1 to G0 transition|up regulation of stationary phase|positive regulation of G1/G0 transition|upregulation of cell cycle quiescence|up regulation of G1/G0 transition|up-regulation of establishment of cell quiescence|activation of establishment of cell quiescence|up-regulation of G1 to G0 transition|upregulation of stationary phase|up regulation of cell cycle quiescence|upregulation of G1/G0 transition Any process that activates or increases the frequency, rate or extent of G1 to G0 transition. GO:0014863 detection of inactivity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014863 The series of events in which a inactivity stimulus is received by a cell or organism and converted into a molecular signal. GO:1903451 negative regulation of G1 to G0 transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903451 down-regulation of cell cycle quiescence|negative regulation of cell cycle quiescence|downregulation of establishment of cell quiescence|down regulation of G1 to G0 transition|down regulation of establishment of cell quiescence|negative regulation of stationary phase|inhibition of establishment of cell quiescence|down-regulation of stationary phase|downregulation of G1 to G0 transition|down-regulation of G1/G0 transition|negative regulation of G1/G0 transition|inhibition of cell cycle quiescence|down-regulation of G1 to G0 transition|downregulation of stationary phase|down regulation of cell cycle quiescence|downregulation of G1/G0 transition|down regulation of stationary phase|downregulation of cell cycle quiescence|inhibition of G1 to G0 transition|down regulation of G1/G0 transition|negative regulation of establishment of cell quiescence|down-regulation of establishment of cell quiescence|inhibition of G1/G0 transition|inhibition of stationary phase Any process that stops, prevents or reduces the frequency, rate or extent of G1 to G0 transition. GO:0014862 regulation of skeletal muscle contraction by chemo-mechanical energy conversion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014862 Any process that modulates the frequency, rate or extent of skeletal muscle contraction by regulating force and velocity of shortening. The force of skeletal muscle contraction is produced by acto-myosin interaction processes through formation of cross bridges. The shortening leads to reduction of length of muscle fiber and sarcomeres. GO:0014861 regulation of skeletal muscle contraction via regulation of action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014861 regulation of skeletal muscle contraction via membrane action potential Any process that modulates the frequency, rate or extent of skeletal muscle contraction by depolarization of muscle membrane and ionic fluxes. CHEBI:38149 19-oxo steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38149 GO:1903450 regulation of G1 to G0 transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903450 regulation of establishment of cell quiescence|regulation of stationary phase|regulation of cell cycle quiescence|regulation of G1/G0 transition Any process that modulates the frequency, rate or extent of G1 to G0 transition. CHEBI:133510 alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133510 GO:0014860 neurotransmitter secretion involved in regulation of skeletal muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014860 neurotransmitter secretion involved in control of skeletal muscle contraction The regulated release of neurotransmitter into the synaptic cleft involved in skeletal muscle contraction. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin. GO:0014866 skeletal myofibril assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014866 The process whose specific outcome is the progression of the skeletal myofibril over time, from its formation to the mature structure. A skeletal myofibril is a myofibril specific to skeletal muscle cells. CHEBI:133511 3-hydroxyoctanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133511 GO:0014865 detection of activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014865 The series of events in which an activity stimulus is received by a cell and converted into a molecular signal. CHEBI:133514 2-hydroxyoctanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133514 CHEBI:133513 3-methylglutaconate anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133513 GO:0014864 detection of muscle activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014864 The series of events in which a muscle activity stimulus is received by a cell and converted into a molecular signal. CHEBI:53784 antispasmodic drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53784 GO:0048291 isotype switching to IgG isotypes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048291 isotype switch recombination to IgG isotypes|class switching to IgG isotypes The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgG isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgG constant region gene segments in the immunoglobulin heavy chain locus. CHEBI:38142 1,2-dihydronaphthalene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38142 GO:0000229 cytoplasmic chromosome biolink:CellularComponent go-plus goslim_generic|goslim_chembl http://purl.obolibrary.org/obo/GO_0000229 cytoplasmic interphase chromosome A chromosome found in the cytoplasm. GO:0048290 isotype switching to IgA isotypes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048290 class switching to IgA isotypes|isotype switch recombination to IgA isotypes The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgA isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgA constant region gene segments in the immunoglobulin heavy chain locus. GO:0000228 nuclear chromosome biolink:CellularComponent go-plus goslim_generic|goslim_chembl http://purl.obolibrary.org/obo/GO_0000228 nuclear interphase chromosome A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact. CHEBI:38141 dihydronaphthalene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38141 GO:0000227 oxaloacetate secondary active transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000227 oxaloacetate carrier activity Enables the transfer of oxaloacetate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. CHEBI:38147 cardiotonic drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38147 GO:0048299 regulation of isotype switching to IgD isotypes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048299 regulation of class switching to IgD isotypes|regulation of class switch recombination to IgD isotypes|regulation of isotype switch recombination to IgD isotypes Any process that modulates the frequency, rate or extent of isotype switching to IgD isotypes. GO:0000233 obsolete cytoplasmic interphase chromosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000233 cytoplasmic interphase chromosome OBSOLETE. A chromosome found in the cytoplasm during interphase. GO:0048298 positive regulation of isotype switching to IgA isotypes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048298 positive regulation of class switch recombination to IgA isotypes|stimulation of isotype switching to IgA isotypes|positive regulation of class switching to IgA isotypes|positive regulation of isotype switch recombination to IgA isotypes|up-regulation of isotype switching to IgA isotypes|upregulation of isotype switching to IgA isotypes|up regulation of isotype switching to IgA isotypes|activation of isotype switching to IgA isotypes Any process that activates or increases the frequency, rate or extent of isotype switching to IgA isotypes. GO:0000232 obsolete nuclear interphase chromosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000232 nuclear interphase chromosome OBSOLETE. A chromosome found in the nucleus during interphase. GO:0000231 obsolete cytoplasmic mitotic chromosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000231 cytoplasmic mitotic chromosome OBSOLETE. A chromosome found in the cytoplasm during mitosis. GO:0048297 negative regulation of isotype switching to IgA isotypes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048297 down-regulation of isotype switching to IgA isotypes|negative regulation of isotype switch recombination to IgA isotypes|inhibition of isotype switching to IgA isotypes|negative regulation of class switching to IgA isotypes|down regulation of isotype switching to IgA isotypes|downregulation of isotype switching to IgA isotypes|negative regulation of class switch recombination to IgA isotypes Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgA isotypes. GO:0048296 regulation of isotype switching to IgA isotypes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048296 regulation of class switch recombination to IgA isotypes|regulation of isotype switch recombination to IgA isotypes|regulation of class switching to IgA isotypes Any process that modulates the frequency, rate or extent of isotype switching to IgA isotypes. GO:0000230 obsolete nuclear mitotic chromosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000230 nuclear mitotic chromosome OBSOLETE. A chromosome found in the nucleus during mitosis. GO:0048295 positive regulation of isotype switching to IgE isotypes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048295 up regulation of isotype switching to IgE isotypes|activation of isotype switching to IgE isotypes|positive regulation of class switch recombination to IgE isotypes|stimulation of isotype switching to IgE isotypes|positive regulation of class switching to IgE isotypes|positive regulation of isotype switch recombination to IgE isotypes|up-regulation of isotype switching to IgE isotypes|upregulation of isotype switching to IgE isotypes Any process that activates or increases the frequency, rate or extent of isotype switching to IgE isotypes. GO:0000237 leptotene biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0000237 Wikipedia:Leptotene|Wikipedia:Meiosis#Leptotene The cell cycle phase which is the first stage of prophase I in meiosis, and during which the chromosomes first become visible. CHEBI:38161 chelator biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38161 GO:0048294 negative regulation of isotype switching to IgE isotypes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048294 down-regulation of isotype switching to IgE isotypes|negative regulation of isotype switch recombination to IgE isotypes|inhibition of isotype switching to IgE isotypes|negative regulation of class switching to IgE isotypes|down regulation of isotype switching to IgE isotypes|downregulation of isotype switching to IgE isotypes|negative regulation of class switch recombination to IgE isotypes Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgE isotypes. GO:0000236 mitotic prometaphase biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0000236 The cell cycle phase in higher eukaryotes which follows mitotic prophase and during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region. Kinetochores mature on each centromere and attach to some of the spindle microtubules. Kinetochore microtubules begin the process of aligning chromosomes in one plane halfway between the poles. CHEBI:38160 3''-deamino-3''-oxonicotianamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38160 GO:0048293 regulation of isotype switching to IgE isotypes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048293 regulation of class switching to IgE isotypes|regulation of class switch recombination to IgE isotypes|regulation of isotype switch recombination to IgE isotypes Any process that modulates the frequency, rate or extent of isotype switching to IgE isotypes. GO:0000235 astral microtubule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000235 Any of the spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell. GO:0048292 isotype switching to IgD isotypes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048292 isotype switch recombination to IgD isotypes|class switching to IgD isotypes The switching of activated B cells from IgM biosynthesis to IgD biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgD constant region gene segments in the immunoglobulin heavy chain locus. GO:0000234 phosphoethanolamine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000234 RHEA:20365|KEGG_REACTION:R02037|MetaCyc:2.1.1.103-RXN|EC:2.1.1.103 S-adenosyl-L-methionine:ethanolamine-phosphate N-methyltransferase activity|phosphoethanolamine methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + ethanolamine phosphate = S-adenosyl-L-homocysteine + N-methylethanolamine phosphate. CHEBI:87195 dicarboximide fungicide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87195 GO:1903459 mitotic DNA replication lagging strand elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903459 lagging strand elongation involved in mitotic nuclear cell cycle DNA replication|lagging strand elongation involved in DNA replication involved in S phase involved in mitotic cell cycle|lagging strand elongation involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|lagging strand elongation involved in mitotic DNA replication|lagging strand elongation involved in DNA replication during S phase involved in mitotic cell cycle|lagging strand elongation involved in DNA replication involved in S-phase involved in mitotic cell cycle Any lagging strand elongation that is involved in mitotic cell cycle DNA replication. CHEBI:133526 oxodocosahexaenoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133526 CHEBI:87197 dichlorophenyl dicarboximide fungicide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87197 GO:1903458 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1903458 GO:1903457 lactate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903457 lactate degradation|lactate breakdown|lactate catabolism The chemical reactions and pathways resulting in the breakdown of lactate. GO:0014879 detection of electrical stimulus involved in regulation of muscle adaptation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014879 The series of events by which an electrical stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation. GO:1903456 positive regulation of androst-4-ene-3,17-dione biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903456 upregulation of androst-4-ene-3,17-dione formation|up-regulation of androst-4-ene-3,17-dione biosynthetic process|up-regulation of androst-4-ene-3,17-dione anabolism|up-regulation of androst-4-ene-3,17-dione biosynthesis|activation of androst-4-ene-3,17-dione anabolism|up-regulation of androst-4-ene-3,17-dione synthesis|activation of androst-4-ene-3,17-dione synthesis|positive regulation of androstenedione biosynthetic process|up-regulation of androst-4-ene-3,17-dione formation|activation of androst-4-ene-3,17-dione formation|up regulation of androstenedione biosynthetic process|upregulation of androst-4-ene-3,17-dione biosynthetic process|upregulation of androst-4-ene-3,17-dione biosynthesis|positive regulation of androst-4-ene-3,17-dione anabolism|up regulation of androst-4-ene-3,17-dione anabolism|positive regulation of androst-4-ene-3,17-dione synthesis|up regulation of androst-4-ene-3,17-dione synthesis|activation of androstenedione|upregulation of androstenedione biosynthetic process|positive regulation of androst-4-ene-3,17-dione formation|up regulation of androst-4-ene-3,17-dione biosynthetic process|up regulation of androst-4-ene-3,17-dione biosynthesis|up regulation of androst-4-ene-3,17-dione formation|positive regulation of androst-4-ene-3,17-dione biosynthesis|activation of androst-4-ene-3,17-dione biosynthesis|activation of androst-4-ene-3,17-dione biosynthetic process|upregulation of androst-4-ene-3,17-dione anabolism|upregulation of androst-4-ene-3,17-dione synthesis|up-regulation of androstenedione biosynthetic process Any process that activates or increases the frequency, rate or extent of androst-4-ene-3,17-dione biosynthetic process. GO:1903455 negative regulation of androst-4-ene-3,17-dione biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903455 inhibition of androstenedione|inhibition of androst-4-ene-3,17-dione formation|inhibition of androst-4-ene-3,17-dione biosynthetic process|inhibition of androst-4-ene-3,17-dione biosynthesis|negative regulation of androstenedione biosynthetic process|down-regulation of androstenedione biosynthetic process|negative regulation of androst-4-ene-3,17-dione anabolism|down-regulation of androst-4-ene-3,17-dione anabolism|downregulation of androstenedione biosynthetic process|negative regulation of androst-4-ene-3,17-dione synthesis|down-regulation of androst-4-ene-3,17-dione synthesis|down regulation of androst-4-ene-3,17-dione biosynthesis|down regulation of androst-4-ene-3,17-dione biosynthetic process|negative regulation of androst-4-ene-3,17-dione formation|down-regulation of androst-4-ene-3,17-dione formation|down regulation of androstenedione biosynthetic process|downregulation of androst-4-ene-3,17-dione anabolism|downregulation of androst-4-ene-3,17-dione biosynthetic process|downregulation of androst-4-ene-3,17-dione biosynthesis|downregulation of androst-4-ene-3,17-dione synthesis|down regulation of androst-4-ene-3,17-dione anabolism|inhibition of androst-4-ene-3,17-dione anabolism|downregulation of androst-4-ene-3,17-dione formation|down regulation of androst-4-ene-3,17-dione synthesis|down-regulation of androst-4-ene-3,17-dione biosynthetic process|down-regulation of androst-4-ene-3,17-dione biosynthesis|negative regulation of androst-4-ene-3,17-dione biosynthesis|inhibition of androst-4-ene-3,17-dione synthesis|down regulation of androst-4-ene-3,17-dione formation Any process that stops, prevents or reduces the frequency, rate or extent of androst-4-ene-3,17-dione biosynthetic process. GO:1903454 regulation of androst-4-ene-3,17-dione biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903454 regulation of androstenedione biosynthetic process|regulation of androst-4-ene-3,17-dione biosynthesis|regulation of androst-4-ene-3,17-dione anabolism|regulation of androst-4-ene-3,17-dione synthesis|regulation of androst-4-ene-3,17-dione formation Any process that modulates the frequency, rate or extent of androst-4-ene-3,17-dione biosynthetic process. GO:1903453 obsolete RNA interference involved in olfactory learning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903453 RNAi involved in olfactory learning|posttranscriptional gene silencing by siRNA involved in olfactory learning OBSOLETE. Any RNA interference that is involved in olfactory learning. GO:0014874 response to stimulus involved in regulation of muscle adaptation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014874 response to stimulus involved in regulation of muscle plasticity Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. This occurs as part of the regulation of muscle adaptation. GO:1903463 regulation of mitotic cell cycle DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903463 regulation of mitotic nuclear cell cycle DNA replication|regulation of DNA replication involved in S phase involved in mitotic cell cycle|regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle|regulation of DNA replication during S phase involved in mitotic cell cycle|regulation of DNA replication involved in S-phase involved in mitotic cell cycle Any process that modulates the frequency, rate or extent of mitotic cell cycle DNA replication. GO:0014873 response to muscle activity involved in regulation of muscle adaptation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014873 response to fatigue|response to muscle activity involved in regulation of muscle plasticity Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus. This process occurs as part of the regulation of muscle adaptation. GO:1903461 Okazaki fragment processing involved in mitotic DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903461 DNA replication, Okazaki fragment processing involved in DNA replication involved in S-phase involved in mitotic cell cycle|DNA replication, Okazaki fragment processing involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|DNA replication, Okazaki fragment processing involved in mitotic nuclear cell cycle DNA replication|DNA replication, Okazaki fragment processing involved in DNA replication during S phase involved in mitotic cell cycle|DNA replication, Okazaki fragment processing involved in DNA replication involved in S phase involved in mitotic cell cycle Any DNA replication, Okazaki fragment processing that is involved in mitotic cell cycle DNA replication. GO:0014872 myoblast division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014872 The process resulting in the physical partitioning and separation of a myoblast into daughter cells. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. GO:1903460 mitotic DNA replication leading strand elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903460 leading strand elongation involved in DNA replication involved in S-phase involved in mitotic cell cycle|leading strand elongation involved in mitotic nuclear cell cycle DNA replication|leading strand elongation involved in mitotic DNA replication|leading strand elongation involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|leading strand elongation involved in DNA replication during S phase involved in mitotic cell cycle|leading strand elongation involved in DNA replication involved in S phase involved in mitotic cell cycle Any leading strand elongation that is involved in mitotic cell cycle DNA replication. CHEBI:38159 3-epi-3-hydroxy-2'-deoxymugineic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38159 CHEBI:133520 N-acetyl-L-alaninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133520 GO:0014871 cross bridge formation involved in regulation of the velocity of shortening in skeletal muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014871 The process in which actin and myosin interact, split ATP and generate force during skeletal muscle contraction. This process is one of the components of the regulation of the force of skeletal muscle contraction. GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014878 response to electrical stimulus involved in regulation of muscle plasticity Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. This process occurs as part of the regulation of muscle adaptation. GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014877 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle inactivity stimulus. This process occurs as part of the regulation of muscle adaptation. GO:0014876 response to injury involved in regulation of muscle adaptation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014876 response to injury involved in regulation of muscle plasticity Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a injury. This process occurs as part of the regulation of muscle adaptation. CHEBI:133525 N-acylphytosphingosine 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133525 GO:0014875 detection of muscle activity involved in regulation of muscle adaptation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014875 detection of fatigue The series of events by which a muscle activity stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation. GO:0000239 pachytene biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0000239 Wikipedia:Pachytene|Wikipedia:Meiosis#Pachytene The cell cycle phase which follows zygotene during prophase I of meiosis, and during which crossing over occurs between a chromatid in one partner and another chromatid in the homologous chromosome. GO:0000238 zygotene biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0000238 Wikipedia:Meiosis#Zygotene|Wikipedia:Zygotene The cell cycle phase which follows leptotene during prophase I of meiosis, and during which each chromosome pairs with its homolog; the two become aligned and crossing over may occur. CHEBI:38151 ferrienterobactin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38151 GO:0014870 response to muscle inactivity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014870 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle inactivity stimulus. CHEBI:38157 iron chelator biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38157 CHEBI:38155 phytosiderophore biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38155 PR:000025513 modified amino-acid residue biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000025513 modified amino acid chain residue|modified protein residue An organic group that results from covalent modification or chemical alteration to the side chain or backbone atoms of an amino acid residue or derivative thereof, where such alteration maintains the integrity of the amino acid chain containing the residue. PR:000001546 prolactin-releasing peptide receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001546 PRLHR|PrRPR|Gm339|G-protein coupled receptor 10|GPR10|GR3|PrRP receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human PRLHR gene or a 1:1 ortholog thereof. PR:000001548 prostaglandin E2 receptor EP4 subtype biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001548 Ptgerep4|PGE receptor EP4 subtype|prostanoid EP4 receptor|PTGER4|PTGER2|prostaglandin E2 receptor EP4|PGE2 receptor EP4 subtype A prostanoid receptor that is a translation product of the human PTGER4 gene or a 1:1 ortholog thereof. The preferred ligand is prostaglandin E2. This receptor is not closely related to other prostaglandin E2 receptors. PR:000001549 prostanoid receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001549 A rhodopsin-like G-protein coupled receptor that is a translation product of the human PTGDR, PTGDR2, PTGER1 to PTGER4, PTGFR, PTGIR, or TBXA2R genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds prostanoids (prostaglandins and thromboxanes). CHEBI:77746 human metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77746 CHEBI:77749 1-palmitoyl-2-(10-hydroperoxy-8E-octadecenoyl)-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77749 PR:000001550 proteinase-activated receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001550 fam:PAR A rhodopsin-like G-protein coupled receptor that is a translation product of the human F2R, or F2RL1 to F2RL3 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds trypsin-related proteinases. The proteinase cleaves the mature peptide, exposing a new amino end. The new N-terminal residues act as a tethered ligand that induces activity. PR:000001555 somatostatin receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001555 A rhodopsin-like G-protein coupled receptor that is a translation product of the human SSTR1 to SSTR5 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds somatostatin. PR:000001557 thyrotropin-releasing hormone receptor type 1 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001557 TRH-R1|TRHR|thyroliberin receptor|TRH-R A thyrotropin-releasing hormone receptor that is a translation product of the human TRHR gene or a 1:1 ortholog thereof. The preferred ligand is thyrotropin-releasing hormone. CHEBI:77740 adenosine 2'-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77740 CHEBI:77756 2-O-glutaroyl-1-O-palmitoyl-sn-glycero-3-phosphocholine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77756 CHEBI:63114 sphingosine-1-phosphate receptor agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63114 CHEBI:77755 10-hydroperoxy-8E-octadecenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77755 CHEBI:77754 9-hydroperoxy-10E-octadecenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77754 CHEBI:77753 1-palmitoyl-2-[(10E)-9-hydroperoxyoctadecenoyl]-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77753 CHEBI:77769 3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77769 CHEBI:77767 3,6-dichlorocatechol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77767 CHEBI:77766 cytidine 2'-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77766 CHEBI:77765 2,4,6-trihydroxybenzophenone(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77765 CHEBI:77764 daidzein(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77764 CHEBI:157597 N-tetracosenoyl-sphingoid base biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_157597 UBERON:0035480 surface of prostate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035480 surface of prostate gland|prostatic surface The external portion of the prostate including the anterior, inferolateral, lateral and posterior surfaces. UBERON:0035483 left suprarenal vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035483 A vein that drains blood from the left adrenal gland into the left renal artery. CHEBI:63131 EDTA(3-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63131 CHEBI:87101 triazole antifungal drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87101 PR:000001590 kappa-type opioid receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001590 kappa-opioid receptor|OPRK1|OPRK|KOR-1|K-OR-1|MSL-1 An opioid receptor protein that is a translation product of the human OPRK1 gene or a 1:1 ortholog thereof. The preferred ligand is dynorphin. CHEBI:87107 7-O-[(2-aminoethyl)phosphoryl]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA(6-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87107 CHEBI:87109 juvenile hormone I carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87109 CHEBI:63137 4-hydroxyproline zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63137 CHEBI:77771 cyanidin 3-O-(6-O-glucosyl-2-O-xylosylgalactoside) betaine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77771 CHEBI:77770 3',5-dihydroxy-3,4',7-trimethoxyflavone(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77770 PR:000001596 lutropin-choriogonadotropic hormone receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001596 LHR|LGR2|LHCGR|luteinizing hormone receptor|LSH-R|lutropin/choriogonadotropin receptor|LCGR|LH/CG-R|LHRHR A glycoprotein hormone receptor that is a translation product of the human LHCGR gene or a 1:1 ortholog thereof. The preferred ligands are lutropin (luteinizing hormone) and choriogonadotropin (choriogonadotropic hormone). CHEBI:77787 1-O-palmityl-2-desoxy-2-amino-sn-glycero-3-phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77787 CHEBI:231935 glycerol 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_231935 CHEBI:77786 1-hexadecyl-2-ammonio-2-deoxy-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77786 GO:0048200 Golgi transport vesicle coating biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048200 dictyosome transport vesicle coating The addition of specific coat proteins to Golgi membranes during the formation of transport vesicles. CHEBI:63150 D-rhamnose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63150 GO:0048208 COPII vesicle coating biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048208 COPII coating of ER-derived vesicle|COPII vesicle coat assembly|COPII vesicle coat formation The addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat. CHEBI:87121 bisanhydrobacterioruberin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87121 CHEBI:87120 4-methylpent-2-enoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87120 GO:0048207 vesicle targeting, rough ER to cis-Golgi biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048207 rough ER to cis-Golgi targeting|vesicle targeting, rough endoplasmic reticulum to cis-Golgi|rough endoplasmic reticulum to cis-Golgi targeting The process in which vesicles are directed to specific destination membranes during transport from the rough endoplasmic reticulum to the cis-Golgi. GO:0048206 vesicle targeting, cis-Golgi to rough endoplasmic reticulum biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048206 vesicle targeting, cis-Golgi to rough ER|vesicle targeting, cis-Golgi to rough endoplasmic reticulum|cis-Golgi to rough ER targeting|cis-Golgi to rough endoplasmic reticulum targeting The process in which vesicles are directed to specific destination membranes during transport from the cis-Golgi to the rough ER. CHEBI:87123 tulipalin B biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87123 CHEBI:87122 monoanhydrobacterioruberin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87122 GO:0048205 COPI coating of Golgi vesicle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048205 COPI vesicle coating|COPI coating of Golgi-derived vesicle The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of transport vesicles, forming a vesicle coat. CHEBI:63151 D-rhamnopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63151 GO:0048204 vesicle targeting, inter-Golgi cisterna biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048204 inter-Golgi cisterna targeting The process in which vesicles are directed to specific destination membranes during transport from one Golgi cisterna to another. CHEBI:63158 EC 2.3.1.21 (carnitine O-palmitoyltransferase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63158 CHEBI:87125 5-epi-valiolone 7-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87125 CHEBI:87124 6-tuliposide B biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87124 GO:0048203 vesicle targeting, trans-Golgi to endosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048203 trans-Golgi to endosome targeting The process in which vesicles are directed to specific destination membranes during transport from the trans-Golgi to the endosome. CHEBI:63157 EC 4.2.1.22 (cystathionine beta-synthase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63157 GO:0048202 clathrin coating of Golgi vesicle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048202 clathrin coating of Golgi-derived vesicle The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles, forming a vesicle coat. CHEBI:63156 EC 1.1.3.13 (alcohol oxidase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63156 GO:0048201 vesicle targeting, plasma membrane to endosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048201 plasma membrane to endosome targeting The process in which vesicles formed at the plasma membrane are directed to specific destinations in endosome membranes, mediated by molecules at the vesicle membrane and target membrane surfaces. PR:000001562 vasopressin/oxytocin receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001562 name: vasopressin and oxytocin receptor A rhodopsin-like G-protein coupled receptor that that is a translation product of the human AVPR1A, AVPR1B, AVPR2, or OXTR genes, 1:1 orthologs thereof, or a semi-ortholog thereof. These receptors bind vasopressin or oxytocin or related nonapeptides. CHEBI:133598 chlortetracycline(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133598 PR:000001564 histamine H3 receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001564 H3R|HH3R|H3 histamine receptor|G-protein coupled receptor 97|HRH3|GPCR97 A histamine receptor that is a translation product of the human HRH3 gene or a 1:1 ortholog thereof. The preferred ligand is histamine. This receptor mediates inhibition of gastric acid release, inhibition of neurotransmitter release, and other diverse effects. CHEBI:77791 luteolin 7-O-beta-D-glucoside(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77791 PR:000001565 H4 histamine receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001565 G-protein coupled receptor 105|GPRv53|H4R|HH4R|AXOR35|GPCR105|Pfi-013|HRH4|SP9144 A histamine receptor that is a translation product of the human HRH4 gene or a 1:1 ortholog thereof. The preferred ligand is histamine. This receptor is expressed primarily in the bone marrow and eosinophils but also in a wide variety of peripheral tissues, including the heart, kidney, liver, lung, pancreas, skeletal muscle, prostate, small intestine, spleen, testis, colon, fetal liver and lymph node. GO:0048209 regulation of vesicle targeting, to, from or within Golgi biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048209 regulation of Golgi vesicle targeting Any process that modulates the frequency, rate, or destination of vesicle-mediated transport to, from or within the Golgi apparatus. CHEBI:77798 melamine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77798 GO:0048211 Golgi vesicle docking biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048211 Golgi vesicle to membrane docking|dictyosome vesicle docking to target membrane|Golgi vesicle docking with target membrane|Golgi-derived vesicle docking The initial attachment of a Golgi transport vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the Golgi vesicle and the target membrane. GO:0048210 Golgi vesicle fusion to target membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048210 Golgi-derived vesicle fusion to target membrane|dictyosome vesicle fusion to target membrane The joining of the lipid bilayer membrane around a Golgi transport vesicle to the target lipid bilayer membrane. CHEBI:63161 glycosyl compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63161 GO:0048219 inter-Golgi cisterna vesicle-mediated transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048219 inter-Golgi cisterna transport The directed movement of substances from one Golgi cisterna to another, mediated by small transport vesicles. CHEBI:63165 ribonucleoside monophosphate oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63165 GO:0048218 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048218 CHEBI:63164 prosolanapyrone III biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63164 GO:0048217 pectic matrix biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0048217 The gel-like pectin matrix consists of the interlinked acidic and neutral pectin networks that are further cross-linked by calcium bridges. Pectins consist largely of long chains of mostly galacturonic acid units (typically 1,4 linkages and sometimes methyl esters). Three major pectic polysaccharides (homogalacturonan, rhamnogalacturonan I and rhamnogalacturonan II) are thought to occur in all primary cell walls. CHEBI:63163 L-cystine anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63163 GO:0048216 negative regulation of Golgi vesicle fusion to target membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048216 inhibition of Golgi vesicle fusion to target membrane|down regulation of Golgi vesicle fusion to target membrane|downregulation of Golgi vesicle fusion to target membrane|down-regulation of Golgi vesicle fusion to target membrane Any process that stops, prevents, or reduces the frequency, rate or extent of Golgi vesicle fusion to target membrane. CHEBI:87114 antibiotic fungicide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87114 GO:0048215 positive regulation of Golgi vesicle fusion to target membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048215 up-regulation of Golgi vesicle fusion to target membrane|upregulation of Golgi vesicle fusion to target membrane|up regulation of Golgi vesicle fusion to target membrane|activation of Golgi vesicle fusion to target membrane|stimulation of Golgi vesicle fusion to target membrane Any process that activates or increases the frequency, rate or extent of Golgi vesicle fusion to target membrane. CHEBI:63169 pyranopterin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63169 CHEBI:87113 antibiotic antifungal drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87113 GO:0048214 regulation of Golgi vesicle fusion to target membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048214 Any process that modulates the frequency, rate or extent of Golgi vesicle fusion to target membrane. CHEBI:63168 perakine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63168 GO:0048213 Golgi vesicle prefusion complex stabilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048213 Golgi vesicle prefusion complex assembly|Golgi-derived vesicle prefusion complex stabilization|dictyosome vesicle prefusion complex stabilisation The binding of specific proteins to the t-SNARE/v-SNARE/SNAP25 complex, by which the Golgi vesicle prefusion complex is stabilized. CHEBI:63167 raucaffrinoline biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63167 GO:0048212 Golgi vesicle uncoating biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048212 Golgi vesicle coat depolymerization|dictyosome vesicle coat depolymerization|Golgi vesicle coat protein depolymerization|Golgi-derived vesicle uncoating The process in which Golgi vesicle coat proteins are depolymerized, and released for reuse. CHEBI:63166 leukotriene D4(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63166 CHEBI:87119 (R)-2-hydroxy-4-methylpentanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87119 PR:000001579 delta-type opioid receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001579 OPRD1|D-OR-1|OPRD|K56|DOR-1|MSL-2|delta-opioid receptor An opioid receptor protein that is a translation product of the human OPRD1 gene or a 1:1 ortholog thereof. The preferred ligands are enkephalins. CHEBI:24367 glycinamide ribonucleotide(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24367 CHEBI:48337 pyrrolopyrazine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48337 UBERON:0001789 outer nuclear layer of retina biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001789 outer nuclear layer|retinal outer nuclear layer|stratum nucleare externum retinae|retina, outer nuclear layer|external nuclear layer|layer of outer granules|ONL|stratum nucleare externum (retina)|neural retina outer nuclear layer|retina outer nuclear layer|retinal outer nuclear layers The layer within the retina where the photoreceptor cell bodies reside. UBERON:0001788 outer limiting layer of retina biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001788 outer limiting membrane|outer limiting membranes|retina outer limiting membrane|stratum limitans externum (retina)|external limiting membrane of retina|external limiting membrane|blood retina barrier|stratum limitans externum retinae|BRB|retina external limiting lamina|external limiting lamina of retina|outer limiting membrane of retina The row of jucntional complexes between the plasma membranes of rod segments and the Muller glia cells; this barrier separates the layer of inner and outer segments of the rods and cones from the outer nuclear layer and forms a blood-retina barrier[MP]. CHEBI:24360 glycerophosphoglycerols biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24360 CHEBI:63970 (5Z,11Z,14Z)-8,9-dihydroxyicosatrienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63970 UBERON:0011112 tibiofibular joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011112 fibulatibial joint|tibiafibular joint|fibulotibial joint A joint that connects the tibia and the fibula. UBERON:0011108 synovial joint of pectoral girdle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011108 joint of shoulder girdle|pectoral girdle joint A synovial joint that is part of a pectoral girdle region. CHEBI:63976 13,14-dihydro-15-keto-PGF2alpha biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63976 UBERON:0011107 synovial joint of pelvic girdle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011107 joint of pelvic girdle|pelvic girdle joint A synovial joint that is part of a pelvic girdle region. UBERON:0001790 outer plexiform layer of retina biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001790 retinal outer plexiform layers|OPL|external plexiform layer|stratum plexiforme externum|outer plexiform layer|retina outer plexiform layer|retinal outer plexiform layer|stratum plexiforme externum retinae|retina, outer plexiform layer The layer within the retina where the bipolar cells synapse with the photoreceptor cells[ZFA]. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells[GO]. CHEBI:87947 9-ribosyl-trans-zeatin 5'-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87947 CHEBI:63979 20-oxoleukotriene B4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63979 CHEBI:63977 12S-HHTrE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63977 UBERON:0001796 aqueous humor of eyeball biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001796 aqueous humor|humor aquosus|aqueous humour A thick watery refractive medium that fills the space between the lens and the cornea[WP]. UBERON:0001795 inner plexiform layer of retina biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001795 retinal internal plexiform layer|retinal inner plexiform layer|retina, inner plexiform layer|stratum plexifome internum|IPL|internal plexiform layer of retina|stratum plexiforme internum retinae|retina inner plexiform layer|inner plexiform layer|stratum plexiforme internum Cytoarchitectural layer of the retina that is made up of a dense reticulum of fibrils formed by interlaced dendrites of retinal ganglion cells and cells of the inner nuclear layer (adapted from Wikipedia) UBERON:0001798 vitreous body biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001798 Gelatinous mucoid tissue that is composed of vitreous humor and fills the cavity behind the crystalline lens of the eye and in front of the retina[MP,modified] UBERON:0001797 vitreous humor biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001797 humor vitreous|humor vitreus|humoral fluid|vitreous humour|whole portion of vitreous humor|ocular fluid|portion of vitreous humor|vitreous fluid|vitreous A transparent, semigelatinous substance that fills the cavity behind the crystalline lens of the eye and in front of the retina UBERON:0001792 ganglionic layer of retina biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001792 retina, ganglion cell layer|retinal ganglion layer|ganglionic cell layer of retina|stratum ganglionicum retinae|retina ganglion layer|stratum ganglionicum (retina)|GCL layer|retina ganglion cell layer|RGC layer|ganglion cell layer|retinal ganglion cell layer Cytoarchitectural layer of retina that contains somata of retinal ganglion cells, bounded by the stratum opticum and the inner plexiform layer UBERON:0001791 inner nuclear layer of retina biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001791 stratum nucleare internum retinae|INL|inner nuclear layer|neural retina inner nuclear layer|retina inner nuclear layer|stratum nucleare internum|retinal inner nuclear layer|layer of inner granules|intermediate cell layer|retina, inner nuclear layer Cytoarchitectural layer of retina containing closely packed cell bodies, the majority of which are bipolar cells (adapted from Wikipedia). UBERON:0001794 inner limiting layer of retina biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001794 internal limiting membrane of retina|inner limiting membranes|inner limiting membrane of retina|stratum limitans internum retinae|inner limiting membrane|ILM|retina internal limiting lamina|internal limiting lamina of retina|retina inner limiting membrane The row of fused Muller cell processes and astrocytes that separates the retinal nerve fiber layer from the vitreous[MP]. UBERON:0001793 nerve fiber layer of retina biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001793 layer of nerve fibres of retina|stratum neurofibrarum (retina)|optic fiber layer|stratum neurofibrum retinae|stratum opticum of retina|optic fiber layer|neural retina nerve fibre layer|optic fiber layers|retina nerve fiber layer|stratum neurofibrarum retinae|nerve fiber layer|layer of nerve fibers of retina layer of the retina formed by expansion of the fibers of the optic nerve CHEBI:73301 tirucallane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73301 UBERON:0001778 ciliary epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001778 epithelium of ciliary body|ciliary body epithelium|ocular ciliary epithelium A double layer covering the ciliary body that produces aqueous humor. UBERON:0001777 substantia propria of cornea biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001777 substantia propria|corneal stroma|substantia propria corneae|stroma of cornea the lamellated connective tissue of the cornea between the Bowman and Descemet membranes dc:description description biolink:OntologyClass go-plus http://purl.org/dc/elements/1.1/description UBERON:0001779 iris stroma biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001779 stroma of iris|iridial stroma The delicate vascular connective tissue that lies between the anterior surface of the iris and the pars iridica retinae. CHEBI:73309 aromatic 2-oxo monocarboxylic acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73309 CHEBI:63983 eoxin A4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63983 CHEBI:63982 Delta(6)-trans-12-epi-leukotriene B4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63982 CHEBI:24373 glycine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24373 CHEBI:63981 6-trans-leukotriene B4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63981 CHEBI:24372 glycine cholesterol esters biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24372 CHEBI:63989 15(R)-HETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63989 UBERON:0001785 cranial nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001785 cranial neural tree organ|nervus cranialis|cranial nerves Cranial nerves are nerves that emerge directly from the brain, in contrast to spinal nerves, which emerge from segments of the spinal cord. UBERON:0001787 photoreceptor layer of retina biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001787 layer of rods and cones|retinal photoreceptor layers|retina photoreceptor layer|stratum segmentorum externorum et internorum retinae|stratum segmentorum externorum et internorum (retina)|retinal photoreceptor layer The layer within the retina where the photoreceptor cell receptor segments reside. UBERON:0001781 layer of retina biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001781 retinal layer|retinal neuronal layer|retina neuronal layer|retina layer Any of the layers that make up the retina[MP]. UBERON:0001780 spinal nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001780 nerve of backbone|nerve of vertebral column|spinal nerves|nerve of spinal column|backbone nerve|spinal column nerve|vertebral column nerve|nerve of spine|spine nerve|nervi spinales|spinal nerve tree the any of the paired peripheral nerves formed by the union of the dorsal and ventral spinal roots from each spinal cord segment[MP,modified] UBERON:0001782 pigmented layer of retina biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001782 RPE|stratum pigmentosum (retina)|pigment epithelium of retina|PRE|epithelium, retinal pigment|outer pigmented layer of retina|stratum pigmentosa retinae|pigmented epithelium|p. pigmentosa retinae|pigmented retina epithelium|stratum pigmentosum retinae|pigmented retinal epithelium|retinal pigmented epithelium|pigmented retina|retinal pigment epithelium|retinal pigment layer A monolayer of pigmented epithelium covering the neural retina; develops from the outer of the two layers of the optic cup[ZFA]. the pigmented cell layer just outside the neurosensory retina that nourishes retinal visual cells, and is firmly attached to the underlying choroid and overlying retinal visual cells[WP]. CHEBI:24346 phosphoglyceric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24346 CHEBI:48313 triphosphate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48313 CHEBI:48315 triphosphate(3-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48315 CHEBI:73315 1-alkylglycerone 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73315 CHEBI:24344 2-phosphoglyceric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24344 CHEBI:48314 triphosphate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48314 UBERON:0001766 anterior chamber of eyeball biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001766 camera anterior bulbi oculi|eye anterior chamber|anterior chamber|camera anterior|anterior chamber of eye|camera oculi anterior|camera anterior bulbi the space in the eye, filled with aqueous humor, and bounded anteriorly by the cornea and a small portion of the sclera and posteriorly by a small portion of the ciliary body, the iris, and part of the crystalline lens CHEBI:48316 triphosphate(4-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48316 CHEBI:73316 2'-deoxyribonucleoside 5'-diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73316 UBERON:0001769 iris biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001769 irides|anterior uvea|irises the adjustable membrane, composed of the stroma and pigmented epithelium, located just in front of the crystalline lens within the eye UBERON:0001768 uvea biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001768 uveal tract|tunica vasculosa of eyeball|tunica vasculosa bulbi|uvea|pars iridica retinae|vascular layer of eyeball|tunica vasculatis oculi the pigmented middle of the three concentric layers that make up an eye, consisting of the iris, ciliary body and choroid[WP,edited]. CHEBI:48318 fragrance biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48318 CHEBI:24347 glycerates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24347 UBERON:0035102 transverse process of caudal vertebra biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035102 A transverse process that is part of a caudal vertebra CHEBI:63994 16-HETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63994 CHEBI:63993 13,14-dihydro-15-oxolipoxin A4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63993 CHEBI:63992 15-oxolipoxin A4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63992 CHEBI:48310 apiitol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48310 CHEBI:63998 19-HETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63998 CHEBI:63995 17-HETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63995 UBERON:0001774 skeletal muscle of trunk biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001774 torso muscle organ|trunk muscle organ|muscle organ of trunk|body musculature|muscle organ of torso|trunk muscle|muscle of trunk|trunk musculature A skeletal muscle organ that is part of the trunk region. UBERON:0001773 sclera biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001773 scleral capsule Opaque fibrous outer layer of the eyeball[ZFA,Kardong,WP]. UBERON:0001776 optic choroid biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001776 choroidea|eye choroid|optic choroid|chorioid|choroid|choroidea|posterior uvea|choroid coat vascular layer containing connective tissue, of the eye lying between the retina and the sclera. The choroid provides oxygen and nourishment to the outer layers of the retina. Along with the ciliary body and iris, the choroid forms the uveal tract[WP]. UBERON:0001775 ciliary body biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001775 ciliary bodies|corpus ciliare|ocular ciliary body|anterior uvea the thickened portion of the vascular tunic, which lies between the choroid and the iris, composed of ciliary muscle and ciliary processes UBERON:0001772 corneal epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001772 epithelial tissue of cornea|epithelium of cornea|anterior endothelium of cornea|epithelium anterius (cornea)|cornea epithelial tissue|epithelium anterius corneae|endothelium camerae anterioris bulbi|external epithelium of cornea|epithelium corneæ anterior layer|anterior corneal epithelium|endothelium corneale|e. anterius corneae|cornea epithelium|epithelium posterius corneae|endothelium anterius corneae the smooth stratified squamous epithelium that covers the outer surface of the cornea CHEBI:73311 adenosine receptor agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73311 UBERON:0001759 vagus nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001759 nerve X|vagus X nerve|vagus|vagus nerve tree|vagus nerve or its root|cranial nerve X|nervus vagus [x]|tenth cranial nerve|CN-X|nervus vagus|vagal nerve|pneuomgastric nerve|10n|vagus nerve [X] Cranial nerve that branches into the lateral (to body sense organs) and the intestino-accessorial (to the skin, muscles of shoulder, hyoid, larynx, gut, lungs, and heart). CHEBI:24356 glycerone phosphates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24356 CHEBI:73325 1-(alk-1-enyl)-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73325 CHEBI:48306 2-aminobut-2-enoic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48306 UBERON:0001756 middle ear biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001756 auris media The middle ear is the air-filled cavity within the skull of vertebrates that lies between the outer ear and the inner ear. It is linked to the pharynx (and therefore to outside air) via the Eustachian tube and in mammals contains the three ear ossicles, which transmit auditory vibrations from the outer ear (via the tympanum) to the inner ear (via the oval window)[GO]. CHEBI:48305 2-aminobut-2-enoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48305 CHEBI:73327 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73327 UBERON:0001758 periodontium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001758 tooth supporting structure|paradentium|periodontal ligament|periodontal membrane The tissues that invest or help to invest and support the teeth, including the periodontal ligament, gingivae, cementum, and alveolar and supporting bone[BTO]. CHEBI:24358 glycerone derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24358 UBERON:0001757 pinna biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001757 auricle of ear|auricle of external ear|auricula (auris externa)|pinnae|auricula|auricle|pinna of ear The part of the ear that projects from the head, connecting to the external acoustic meatus. CHEBI:48307 L-apiitol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48307 CHEBI:87950 9-ribosyl-trans-zeatin 5'-diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87950 CHEBI:24353 glycerol ether biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24353 CHEBI:48300 D-threitol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48300 CHEBI:87953 9-ribosyl-trans-zeatin 5'-triphosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87953 CHEBI:38999 GABA-gated chloride channel antagonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38999 UBERON:0001763 odontogenic papilla biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001763 dentinal papilla|dental papilla|pharyngeal tooth mesenchyme|tooth mesenchyme|dermal papilla|papilla dentis|odontogenic condensation A condensation of odontoblasts that forms the part of a tooth germ that gives rise to dentin and pulp in the mature tooth. It lies below a cellular aggregation known as the enamel organ. CHEBI:48309 N-formyl-L-glutamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48309 UBERON:0001765 mammary duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001765 lactiferous tubule|galactophorous tubule|lactiferous duct|mammary gland duct|galactophorous duct|ductus lactiferi|lactiferous gland duct|mammilary duct Epithelial tube that transports milk[GO]. CHEBI:73320 1-(alk-1-enyl)-2-acyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73320 CHEBI:73322 1-(alk-1-enyl)-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73322 CHEBI:73335 ultraviolet filter biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73335 CHEBI:24323 glutamyl-L-amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24323 CHEBI:73336 vulnerary biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73336 CHEBI:24321 glutamo group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24321 CHEBI:24326 glutaramic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24326 CHEBI:24320 glutaminyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24320 UBERON:0011159 primary subdivision of cranial skeletal system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011159 UBERON:0011158 primary subdivision of skull biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011158 skull subdivision|subdivision of skull The skull can be divided into two: the neurocranium and the facial skeleton UBERON:0011156 facial skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011156 viscerocranium|facial skeleton|facial bone|ossa faciei|ossa facialia Subdivision of skull that consists of the facial bones. CHEBI:24329 glutarate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24329 CHEBI:73333 scabicide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73333 CHEBI:73332 1-alkyl-2-acyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73332 CHEBI:73346 trans-coumaryl acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73346 CHEBI:24335 glutathione conjugate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24335 CHEBI:24333 glutaryl-CoAs biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24333 CHEBI:24337 glutathione derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24337 UBERON:0011143 upper urinary tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011143 Subdivision of urinary system which consists of the kidney and the ureters. UBERON:0011142 axial ossicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011142 ossicle of postcranial-axial skeleton|vertebral ossicle|ossicle of axial skeleton Ossicle that is part of the axial skeleton. UBERON:0011141 appendicular ossicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011141 ossicle of appendicular skeleton Ossicle that is part of the appendicular skeleton. UBERON:0011148 submucosal gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011148 Gland of the lamina epithelialis mucosae which perforate the lamina muscularis, with their adenomeres located in the submucosal connective tissue. CL:1001611 cerebellar neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001611 cerebellum neuron Neuron of the cerebellum. CL:1001610 bone marrow hematopoietic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001610 bone marrow poietic cells|bone marrow hematopoietic cells Hematopoietic cells resident in the bone marrow. Include: hematopoietic stem cells (lymphoid stem cells and myeloid stem cells) and the precursor cells for thrombocytes, erythrocytes, basophils, neutrophils, eosinophils, monocytes and lymphocytes. CHEBI:38976 alkylbenzene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38976 CHEBI:38975 methylbenzene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38975 UBERON:0011139 synovial limb joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011139 synovial joint of free limb segment Any synovial joint that is part of a (free) limb. UBERON:0011138 postcranial axial skeletal system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011138 post-cranial axial skeletal system|axial skeletal system Subdivision of the skeletal system which consists of the postcranial axial skeleton plus associated joints. PR:000001753 transcription factor NF-kappa-B subunit biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001753 transcription factor NF-kappa-B A protein with a core domain composition consisting of a Rel homology domain (RHD) (Pfam:PF00554), an IPT/TIG domain (Pfam:PF01833), six copies of the Ankyrin repeat (Pfam:PF00023), a Death domain (Pfam:PF00531) and a C-terminal PEST region. PO:0025606 native plant cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025606 A plant cell (PO:0009002) that is either part of a multicellular whole plant (PO:0000003) 'in vivo' or a unicellular organism 'in natura' (i.e. part of a natural environment). CHEBI:73343 trans-anol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73343 CHEBI:24302 glucosiduronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24302 CHEBI:24301 glucuronolactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24301 CHEBI:73359 alpha-CH2-containing aldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73359 UBERON:0011133 intermetatarsal joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011133 A joint that connects two adjacent metatarsals UBERON:0011132 intercarpal joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011132 intercarpal|intercarpal articulation|carpal joint|midcarpal articulation A skeletal joint that connects two carpal bones. UBERON:0011131 intermetacarpal joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011131 intermetacarpal|intermetacarpal articulation A skeletal joint that connects two adjacent metacarpals[FMA,modified]. UBERON:0011137 axial skeletal system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011137 Subdivision of the skeletal system which consists of the axial skeleton plus associated joints. NCBITaxon:85512 Dicondylia organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_85512 UBERON:0011134 nonsynovial joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011134 solid joint Joint in which the articulating bones or cartilages are connected by ligaments or fibrocartilage without an intervening synovial cavity. Examples: sagittal suture, inferior tibiofibular syndesmosis, costochondral joint, pubic symphysis. CHEBI:38941 schistosomicide drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38941 CHEBI:24309 glutaconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24309 CHEBI:24313 glutamic semialdehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24313 CHEBI:24311 glutaconyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24311 CHEBI:24317 L-glutamine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24317 UBERON:0001799 vitreous chamber of eyeball biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001799 vitreous chamber|camera vitrea bulbi|camera vitrea|postremal chamber of eyeball|postremal chamber|camera postrema|camera postrema bulbi oculi The chamber in the eyeball enclosing the vitreous humor, bounded anteriorly by the lens and ciliary body and posteriorly by the posterior wall of the eyeball[BTO,modified]. CHEBI:24315 glutamic acid derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24315 CHEBI:87990 alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87990 CHEBI:87992 beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87992 UBERON:0011120 laryngeal joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011120 laryngeal articulation|joint of larynx A skeletal joint that connects a laryngeal cartilage. CHEBI:87994 alpha-Neup5Ac-(2->3)-beta-D-Galp-(1->3)-beta-D-GalpNAc-(1->4)-[alpha-Neup5Ac-(2->8)-alpha-Neup5Ac-(2->8)-alpha-Neup5Ac-(2->3)]-beta-D-Galp-(1->4)-beta-D-Glcp-(1<->1')-Cer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87994 CHEBI:87996 3-(m-hydroxyphenyl)propanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87996 UBERON:0011119 carpometacarpal joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011119 articulationes carpometacarpeæ|carpometacarpal articulation|CMJ|carpometacarpal The carpometacarpal joints (CMC) are joints in the wrist that articulates the distal row of carpal bones and the proximal bases of the metacarpal bones. UBERON:0011118 tarsometatarsal joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011118 tarso-metatarsal join|tarsometatarsal articulation|cuboideometatarsal|tarsometatarsal|Lisfranc joint|articulationes tarsometatarsales The tarsometatarsal articulations are arthrodial joints in the pes. CHEBI:87997 3-aminobutyrate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87997 CHEBI:38958 indole alkaloid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38958 CHEBI:38956 ectoparasiticide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38956 CHEBI:73360 EC 3.4.11.18 (methionyl aminopeptidase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73360 CHEBI:24319 EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24319 CHEBI:73361 methionine aminopeptidase 2 inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73361 CHEBI:24318 glutamine family amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24318 UBERON:0001705 nail biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001705 claw|talon|nail/claw A horn-like keratin structure covering the dorsal aspect of the terminal phalanges of fingers and toes[WP]. GO:0000442 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000442 GO:0097354 prenylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097354 The covalent attachment of a prenyl group to a molecule; geranyl, farnesyl, or geranylgeranyl groups may be added. GO:0000441 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000441 GO:0097353 centrolateral pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097353 mediolateral pattern formation The regionalization process in which the areas along the centrolateral axis are established that will lead to differences in cell differentiation, or in which cells interpret a specific environment. GO:0000440 core TFIIH complex portion of NEF3 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000440 SSL2-core TFIIH complex portion of NEF3 complex The core TFIIH complex when it is part of the nucleotide-excision repair factor 3 (NEF3). UBERON:0001707 nasal cavity biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001707 cavum nasi|cavity of nose|cavity of olfactory apparatus|nasal conduit space|cavitas nasi|olfactory chamber cavity|nasal canal|olfactory chamber|cavitas nasalis|olfactory cavity|olfactory pit|nasal fossa|nasal pit An anatomical cavity that is part of the olfactory apparatus. This includes the space bounded anteriorly by the nares and posteriorly by the choanae, when these structures are present. GO:0097356 perinucleolar compartment biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097356 perinucleolar region The perinucleolar compartment (PNC) is a subnuclear structure associated with, but structurally distinct from, the nucleolus. The PNC contains large amounts of the heterogeneous nuclear ribonucleoprotein complex (hnRNP) called hnRNP 1 (PTB). Many RNA binding proteins as well as RNA polymerase III transcripts are highly enriched in this compartment. PTB and pol III transcripts are required for the integrity of the PNC. GO:0097355 protein localization to heterochromatin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097355 protein localisation to heterochromatin Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into heterochromatin. GO:0000446 nucleoplasmic THO complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000446 The THO complex when it is acting as a nuclear complex that is required for transcription elongation through genes containing tandemly repeated DNA sequences. In S. cerevisiae, it is composed of four subunits: Hpr1, Tho2, Thp2, and Mft1, while the human complex is composed of 7 subunits. UBERON:0001701 glossopharyngeal ganglion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001701 petrosal ganglion|gIX|ganglion of glossopharyngeal nerve|glossopharyngeal IX ganglion|ganglion of glosspharyngeal nerve The group of neuron cell bodies associated with the ninth cranial nerve. GO:0097350 neutrophil clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097350 The selective elimination of senescent neutrophils from the body by autoregulatory mechanisms. UBERON:0001700 geniculate ganglion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001700 ganglion geniculi|gVII|facial VII ganglion|ganglion geniculi nervi facialis|geniculate|internal genu|facial ganglion|genicular ganglion|geniculate ganglion|ganglion genicularum the group of sensory neuron cell bodies associated with the facial nerve (seventh cranial nerve) GO:0000445 THO complex part of transcription export complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000445 THO complex part of TREX complex The THO complex when it is part of the TREX (TRanscription EXport) complex that is involved in coupling transcription to export of mRNAs to the cytoplasm. In S. cerevisiae, it is composed of four subunits: Hpr1, Tho2, Thp1, and Mft1, while the human complex is composed of 7 subunits. GO:0097352 autophagosome maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097352 autophagic vacuole fusion|autophagic vacuole maturation|autophagosome fusion Removal of PI3P and Atg8/LC3 after the closure of the phagophore and before the fusion with the endosome/lysosome (e.g. mammals and insects) or vacuole (yeast), and that very likely destabilizes other Atg proteins and thus enables their efficient dissociation and recycling. UBERON:0001703 neurocranium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001703 brain case|brain pan|brain box|braincase Subdivision of skeletal system that surrounds and protects the brain. Includes the skull base, sensory capsules and the central part of the skull roof. GO:0000444 MIS12/MIND type complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000444 Mis12 complex A multiprotein kinetochore subcomplex that binds to centromeric chromatin and forms part of the inner kinetochore. It helps to recruit outer kinetochore subunits that will bind to microtubules. In humans, it consists of MIS12, DSN1, NSL1 and PMF1. GO:0097351 toxin-antitoxin pair type II binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097351 Interacting selectively and non-covalently with a toxic protein, disabling its function. There may be more than one antitoxin to a toxic protein. Instances of this activity are known only in prokaryotes, where the toxic protein may be a ribonuclease, a DNA gyrase, or other. GO:0000443 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000443 UBERON:0001709 upper jaw region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001709 dorsal pharyngeal arch 1|maxillary part of mouth|upper pharyngeal jaws|palatoquadrate arch|maxillary part of mouth proper|dorsal mandibular arch|alveolodental arch of bimaxilla Subdivision of head that consists of the upper jaw skeletal elements plus associated soft tissue (skin, lips, muscle)[cjm]. UBERON:0001708 jaw skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001708 jaws|pharyngeal arch 1 skeleton|visceral arch 1|anterior splanchnocranium|mandibular arch|mandibular arch skeleton|jaw|jaw cartilage|oral jaw skeleton Subdivision of skeleton which includes upper and lower jaw skeletons. GO:0000449 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000449 Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. For example, primary ribosomal RNA transcripts containing three genes, in this order, are produced in E. coli and other prokaryotic species. Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript. GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000448 cleavage at C2|cleavage in ITS2 of tricistronic rRNA transcript to separate 5.8S and LSU rRNAs (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Endonucleolytic cleavage within ITS2 between the 5.8S rRNA and the LSU-rRNA of an rRNA molecule originally produced as a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. UBERON:0001710 lower jaw region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001710 mandibular part of mouth|mandibular series|lower part of mouth Subdivision of head that consists of the lower jaw skeletal elements plus associated soft tissue (skin, lips, muscle)[cjm]. GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000447 endonucleolytic cleavage at A2 Endonucleolytic cleavage between the SSU-rRNA and the 5.8S rRNA of an rRNA molecule originally produced as a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. GO:0097358 D-leucyl-tRNA(Leu) deacylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097358 Catalysis of the reaction: D-leucyl-tRNA(Leu) = D-leucine + tRNA(Leu). Hydrolysis of the removal of D-leucine from residues in charged tRNA(Leu). GO:0097357 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0097357 GO:0097359 UDP-glucosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097359 The covalent attachment of a UDP-glucose residue to a substrate molecule. GO:0000453 enzyme-directed rRNA 2'-O-methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000453 The addition of methyl groups to the 2'-oxygen atom of nucleotide residues in an rRNA molecule during ribosome biogenesis where the methylase specifies the site that becomes methylated without using a guide RNA. GO:0097365 stretch-activated, cation-selective, calcium channel activity involved in regulation of cardiac muscle cell action potential biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097365 Enables the transmembrane transfer of a calcium ion by a channel that opens in response to a mechanical stress in the form of stretching, and contributing to the regulation of action potential in a cardiac muscle cell. GO:0097364 stretch-activated, cation-selective, calcium channel activity involved in regulation of action potential biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097364 Enables the transmembrane transfer of a calcium ion by a channel that opens in response to a mechanical stress in the form of stretching, and contributing to the regulation of action potential. GO:0000452 snoRNA guided rRNA 2'-O-methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000452 snoRNA guided rRNA 2'-O-ribose methylation The posttranscriptional addition of methyl groups to the 2'-oxygen atom of nucleotide residues in an rRNA molecule during ribosome biogenesis using a snoRNA guide that targets the position of methylation. GO:0097367 carbohydrate derivative binding biolink:MolecularActivity go-plus goslim_mouse|goslim_agr http://purl.obolibrary.org/obo/GO_0097367 Interacting selectively and non-covalently with a carbohydrate derivative. GO:0000451 rRNA 2'-O-methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000451 The addition of a methyl group to the 2'-oxygen atom of a nucleotide residue in an rRNA molecule during ribosome biogenesis. GO:0000450 cleavage of bicistronic rRNA transcript (SSU-rRNA, LSU-rRNA) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000450 Endonucleolytic cleavage of pre-rRNAs originally produced as a bicistronic rRNA transcript that contains the SSU-rRNA and the LSU-rRNA in that order from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with two genes in this order are produced in Archaeal species. GO:0097366 response to bronchodilator biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0097366 response to bronchodilator agent|response to broncholytic agent Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bronchodilator stimulus. A bronchodilator is a chemical that causes an increase in the expansion of a bronchus or bronchial tubes. GO:0097361 CIA complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097361 cytosolic iron-sulfur protein assembly complex The cytosolic iron-sulfur protein assembly (CIA) complex mediates the incorporation of iron-sulfur clusters into apoproteins involved in DNA metabolism and genomic integrity. GO:0000457 endonucleolytic cleavage between SSU-rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000457 Endonucleolytic cleavage to separate a pre-SSU-rRNA from a pre-LSU-rRNA originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript. GO:0097360 chorionic trophoblast cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097360 The multiplication or reproduction of chorionic trophoblast cells, resulting in the expansion of their population. GO:0000456 obsolete dimethylation involved in SSU-rRNA maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000456 OBSOLETE. Dimethylation of the N6 amino groups of two consecutive adenosine residues near the 3'-end of the SSU rRNA. This process has been conserved from bacteria to eukaryotes. GO:0097363 protein O-GlcNAc transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097363 Reactome:R-HSA-9687828|EC:2.4.1.255 UDP-N-acetyl-D-glucosamine:protein-O-beta-N-acetyl-D-glucosaminyl transferase|O-linked N-acetylglucosaminyltransferase|O-GlcNAc transferase|OGTase Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + [protein]-L-serine = UDP + [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine, or UDP-N-acetyl-D-glucosamine + [protein]-L-threonine = UDP + [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine. GO:0000455 enzyme-directed rRNA pseudouridine synthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000455 The intramolecular conversion of uridine to pseudouridine during ribosome biogenesis where the enzyme specifies the site that becomes pseudouridylated without using a guide RNA. GO:0097362 MCM8-MCM9 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097362 A hexameric protein complex composed of MCM8 and MCM9 and involved in homologous recombination repair following DNA interstrand cross-links. GO:0000454 snoRNA guided rRNA pseudouridine synthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000454 The intramolecular conversion of uridine to pseudouridine in an rRNA molecule during ribosome biogenesis using a snoRNA guide that targets the position of pseudouridylation. CHEBI:63902 (+)-thujan-3-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63902 CHEBI:63900 3,16-dihydroxyhexadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63900 CHEBI:63906 cholest-5-en-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63906 GO:0000459 exonucleolytic trimming involved in rRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000459 exonucleolytic trimming during rRNA processing Exonucleolytic digestion of a pre-rRNA molecule in the process to generate a mature rRNA molecule. CHEBI:63904 3,16-dihydroxyhexadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63904 GO:0000458 endonucleolytic cleavage between LSU-rRNA and 5S rRNA of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000458 Endonucleolytic cleavage to separate a pre-LSU-rRNA from a pre-5S rRNA originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript. GO:0097369 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0097369 GO:0097368 establishment of Sertoli cell barrier biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097368 establishment of SCB|establishment of BTB|establishment of blood-testis barrier Establishment of a structure near the basement membrane in adjacent Sertoli cells of the seminiferous epithelium for maintaining spermatogenesis. The structure consists of tight junctions, basal ectoplasmic specializations, and desmosome-like junctions. GO:0097332 response to antipsychotic drug biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097332 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antipsychotic drug stimulus. Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. GO:0000420 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000420 GO:0097331 response to cytarabine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097331 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytarabine stimulus. GO:0097334 response to perphenazine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097334 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a perphenazine stimulus. Perphenazine is a phenothiazine derivative having a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at the N-10 position. GO:0097333 response to olanzapine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097333 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an olanzapine stimulus. GO:0000424 micromitophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000424 Degradation of a mitochondrion by lysosomal microautophagy. GO:0000423 mitophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000423 macromitophagy The selective autophagy process in which a mitochondrion is degraded by macroautophagy. GO:0000422 autophagy of mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000422 Wikipedia:Autophagy_(cellular)#Selective_autophagy|Wikipedia:Mitophagy mitochondrion autophagy|mitophagy The autophagic process in which mitochondria are delivered to a type of vacuole and degraded in response to changing cellular conditions. GO:0097330 response to 5-fluoro-2'-deoxyuridine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097330 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 5-fluoro-2'-deoxyuridine stimulus. 5-fluoro-2'-deoxyuridine is a pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; it is used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract. CL:1001609 muscle fibroblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001609 Fibroblast from muscle organ. GO:0000421 autophagosome membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000421 autophagic vacuole membrane The lipid bilayer surrounding an autophagosome, a double-membrane-bounded vesicle in which endogenous cellular material is sequestered. CL:1001603 lung macrophage biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001603 lung macrophages Circulating macrophages and tissue macrophages (alveolar macrophages) of lung. CL:1001602 cerebral cortex endothelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001602 endothelial cells of cerebral cortex|cerebral cortex endothelial cells Endothelial cells forming the walls of the capillaries within the cerebral cortex. CHEBI:48396 7(1)-hydroxychlorophyllide a biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48396 CL:1001601 adrenal gland glandular cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001601 suprarenal gland glandular cell|adrenal glandular cell|adrenal gland glandular cells Hormone secreting cell located in the cortex of adrenal gland. Glandular cells in the adrenal cortex secrete mineralocorticoids, glucocorticoids and androgens. CHEBI:48399 13(2)-carboxypyropheophorbide a biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48399 CHEBI:48398 pyropheophorbide a biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48398 CHEBI:63912 19-hydroxyprostaglandin H2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63912 GO:0000428 DNA-directed RNA polymerase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000428 A protein complex that possesses DNA-directed RNA polymerase activity. GO:0097339 glycolate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097339 glycolate membrane transport The process in which glycolate is transported across a membrane. Glycolate is the anion of hydroxyethanoic acid (glycolic acid). GO:0000427 plastid-encoded plastid RNA polymerase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000427 An RNA polymerase complex containing polypeptides encoded by the plastid genome. Plastid-encoded DNA-directed RNA polymerases resemble eubacterial multisubunit RNA polymerases, with a core composed of alpha, beta, and beta-prime subunits. Some forms contain multiple additional subunits. An additional sigma factor subunit is required for promoter recognition. GO:0000426 micropexophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000426 Degradation of a peroxisome by lysosomal microautophagy. GO:0000425 pexophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000425 macropexophagy The selective autophagy process in which a peroxisome is degraded by macroautophagy. GO:0097336 response to risperidone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097336 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a risperidone stimulus. GO:0097335 response to quetiapine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097335 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a quetiapine stimulus. GO:0097338 response to clozapine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097338 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a clozapine stimulus. GO:0000429 carbon catabolite regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000429 regulation of transcription from RNA polymerase II promoter by carbon catabolites A transcription regulation process in which the presence of one carbon source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources. GO:0097337 response to ziprasidone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097337 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ziprasidone stimulus. Ziprasidone is a piperazine compound having 1,2-benzothiazol-3-yl- and 2-(6-chloro-1,3-dihydro-2-oxindol-5-yl)ethyl substituents attached to the nitrogen atoms. GO:0097343 ripoptosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097343 The aggregation, arrangement and bonding together of a set of components to form a ripoptosome, a protein complex whose formation can induce an extrinsic apoptotic signaling pathway or a necroptotic signaling pathway. The composition of this protein complex may depend on several factors including nature of the signal, cell type and more. GO:0000431 regulation of transcription from RNA polymerase II promoter by galactose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000431 Any process involving galactose that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:0097342 ripoptosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097342 Tnfr1-CII|TNFR1 complex II|necrosome A protein complex whose core components are the receptor-interacting serine/threonine-protein kinases RIPK1 and RIPK3 (also called RIP1 and RIP3). Formation of the ripoptosome can induce an extrinsic apoptotic signaling pathway or a necroptotic signaling pathway. The composition of this protein complex may depend on several factors including nature of the signal, cell type and more. GO:0000430 regulation of transcription from RNA polymerase II promoter by glucose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000430 Any process involving glucose that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:0097345 mitochondrial outer membrane permeabilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097345 mitochondrial outer membrane permeabilization|mitochondrion outer membrane permeabilization|mitochondrial outer membrane permeabilization during apoptotic cell death|MOMP The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of the apoptotic signaling pathway. GO:0097344 Rix1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097344 IPI complex A protein complex that comprises Rix1p, Ipi1p and Ipi3p, and is required for processing of ITS2 sequences from 35S pre-rRNA. The Rix1 complex has been identified in budding yeast and fission yeast, and members of this complex are conserved in higher eukaryotes. GO:0000435 positive regulation of transcription from RNA polymerase II promoter by galactose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000435 stimulation of transcription from RNA polymerase II promoter by galactose|up-regulation of transcription from RNA polymerase II promoter by galactose|activation of transcription from RNA polymerase II promoter by galactose|up regulation of transcription from RNA polymerase II promoter by galactose|upregulation of transcription from RNA polymerase II promoter by galactose Any process involving galactose that activates or increases the rate of transcription from an RNA polymerase II promoter. GO:0000434 carbon catabolite repression of transcription from RNA polymerase II promoter by galactose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000434 down-regulation of transcription from RNA polymerase II promoter by galactose|downregulation of transcription from RNA polymerase II promoter by galactose|down regulation of transcription from RNA polymerase II promoter by galactose|inhibition of transcription from RNA polymerase II promoter by galactose Any process involving galactose that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter. GO:0097341 zymogen inhibition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097341 prevention of zymogen activation Any process that prevents the proteolytic processing of an inactive enzyme to an active form. GO:0000433 carbon catabolite repression of transcription from RNA polymerase II promoter by glucose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000433 downregulation of transcription from RNA polymerase II promoter by glucose|down regulation of transcription from RNA polymerase II promoter by glucose|inhibition of transcription from RNA polymerase II promoter by glucose|down-regulation of transcription from RNA polymerase II promoter by glucose A transcription regulation process in which the presence of glucose leads to a decrease in the frequency, rate, or extent of transcription of specific RNA polymerase II-transcribed genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances. GO:0097340 inhibition of cysteine-type endopeptidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097340 prevention of cysteine-type endopeptidase activity|inhibition of caspase activity|prevention of caspase activity Any process that prevents the activation of an inactive cysteine-type endopeptidase. GO:0000432 positive regulation of transcription from RNA polymerase II promoter by glucose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000432 up regulation of transcription from RNA polymerase II promoter by glucose|upregulation of transcription from RNA polymerase II promoter by glucose|stimulation of transcription from RNA polymerase II promoter by glucose|up-regulation of transcription from RNA polymerase II promoter by glucose|activation of transcription from RNA polymerase II promoter by glucose Any process involving glucose that activates or increases the rate of transcription from an RNA polymerase II promoter. GO:0000439 transcription factor TFIIH core complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0000439 core TFIIH complex|SSL2-core TFIIH complex The 7 subunit core of TFIIH that is a part of either the general transcription factor holo-TFIIH or the nucleotide-excision repair factor 3 complex. In S. cerevisiae/humans the complex is composed of: Ssl2/XPB, Tfb1/p62, Tfb2/p52, Ssl1/p44, Tfb4/p34, Tfb5/p8 and Rad3/XPD. GO:0000438 core TFIIH complex portion of holo TFIIH complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000438 SSL2-core TFIIH complex portion of holo TFIIH complex The core TFIIH complex when it is part of the general transcription factor TFIIH. GO:0000437 carbon catabolite repression of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000437 negative regulation of transcription from RNA polymerase II promoter by carbon catabolites A transcription regulation process in which the presence of one carbon source leads to a decrease in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources. GO:0000436 carbon catabolite activation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000436 positive regulation of transcription from RNA polymerase II promoter by carbon catabolites Any process involving carbon catabolites that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:0097347 TAM protein secretion complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097347 translocation and assembly module protein complex A heterooligomeric protein complex that spans the bacterial periplasm and enables the secretion of adhesin proteins in Gram-negative bacteria. In Citrobacter rodentium, Salmonella enterica and Escherichia coli, the TAM complex consists of an Omp85-family protein, TamA, in the outer membrane and TamB in the inner membrane. GO:0097346 INO80-type complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097346 A chromatin remodeling protein complex initially purified from S. cerevisiae and containing more than 10 subunits, including the SWR1-related complexes. INO80 (inositol requiring 80)-type complexes have diverse functions, including promoting transcriptional activation and DNA repair. GO:0097349 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0097349 GO:0097348 host cell endocytic vesicle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097348 The lipid bilayer surrounding a host cell endocytic vesicle. GO:0097398 cellular response to interleukin-17 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097398 cellular response to IL-17 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-17 stimulus. UBERON:0001749 parenchyma of parathyroid gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001749 parathyroid gland parenchyma|parathyroid parenchyma|parenchyma of parathyroid A parenchyma that is part of a parathyroid gland [Automatically generated definition]. CHEBI:48379 isourea biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48379 GO:0097397 cellular response to interleukin-32 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097397 cellular response to IL-32 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-32 stimulus. CHEBI:48378 carboximidic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48378 UBERON:0001748 capsule of parathyroid gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001748 parathyroid gland capsule The dense and irregular connective tissue capsule surrounding a parathyroid gland. GO:0097399 interleukin-32-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097399 IL-32-mediated signaling pathway|IL-32-mediated signalling pathway|interleukin-32-mediated signalling pathway A series of molecular signals initiated by the binding of interleukin-32 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. UBERON:0001745 secondary nodular lymphoid tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001745 peripheral lymphoid tissue|secondary lymphoid nodule|secondary lymphoid tissue A lymphoid follicle that contains a germinal center. GO:0097394 telomeric repeat-containing RNA transcription by RNA polymerase II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097394 telomeric repeat-containing RNA transcription from RNA pol II promoter|TERRA RNA transcription from RNA pol II promoter|telomeric RNA transcription from Pol II promoter The synthesis of telomeric repeat-containing RNA from a DNA template by RNA polymerase II (Pol II), originating at a Pol II promoter. GO:0000402 crossed form four-way junction DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000402 crossed form Holliday junction binding Interacting selectively and non-covalently with DNA containing the crossed form of a four-way junction, also known as a Holliday junction, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices. The crossed form of a four-way junction cannot be diagrammed without any of the strands crossing over, and instead contains a single crossover between two of the strands. GO:0000401 open form four-way junction DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000401 open form Holliday junction binding Interacting selectively and non-covalently with DNA containing the open form of a four-way junction, also known as a Holliday junction, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices. The open form of a four-way junction can be diagrammed without any of the strands crossing over. GO:0097393 telomeric repeat-containing RNA transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097393 TERRA transcription The synthesis of telomeric repeat-containing RNA from a DNA template. A telomere is a complex of DNA and proteins that seals the end of a chromosome. UBERON:0001744 lymphoid tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001744 lymphocytic tissue|lymphatic tissue Portion of connective tissue with various types of white blood cells enmeshed in it, most numerous being the lymphocytes[WP]. UBERON:0001747 parenchyma of thyroid gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001747 thyroid gland parenchyma|parenchyma of thyroid follicle|thyroid parenchyma|thyroid follicle parenchyma|parenchyma glandulae thyroideae|parenchyma of thyroid|parenchyma of thyroid gland follicle|thyroid gland follicle parenchyma A parenchyma that is part of a thyroid follicle [Automatically generated definition]. GO:0000400 four-way junction DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000400 forked DNA binding|Holliday junction binding Interacting selectively and non-covalently with DNA containing four-way junctions, also known as Holliday junctions, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices. GO:0097396 response to interleukin-17 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097396 response to IL-17 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-17 stimulus. UBERON:0001746 capsule of thyroid gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001746 capsula fibrosa glandulae thyroideae|thyroid capsule|fibrous capsule of thyroid gland|thyroid gland capsule GO:0097395 response to interleukin-32 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097395 response to IL-32 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-32 stimulus. GO:0097390 chemokine (C-X-C motif) ligand 12 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0097390 CXCL12 production The appearance of chemokine (C-X-C motif) ligand 12 (CXCL12) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0097392 chemokine (C-X-C motif) ligand 16 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0097392 CXCL16 production The appearance of chemokine (C-X-C motif) ligand 16 (CXCL16) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0097391 chemokine (C-X-C motif) ligand 13 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0097391 CXCL13 production The appearance of chemokine (C-X-C motif) ligand 13 (CXCL13) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. CHEBI:48377 imidic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48377 CHEBI:48376 carbamimidic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48376 CHEBI:63932 EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63932 CHEBI:63931 L-erythro-biopterin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63931 CHEBI:63933 Aroclor 1254 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63933 UBERON:0001752 enamel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001752 tooth enamel|enameloid|enamel tissue|enamel of tooth A dentine-like hypermineralized substance that covers the tooth tip. Enamel's primary mineral is hydroxylapatite, which is a crystalline calcium phosphate. Unlike dentin and bone, enamel does not contain collagen. Instead, it has two unique classes of proteins called amelogenins and enamelins[WP]. GO:0000406 double-strand/single-strand DNA junction binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000406 Interacting selectively and non-covalently with a region of DNA that contains double-stranded DNA flanked by a region of single-stranded DNA. UBERON:0001751 dentine biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001751 predentin|dentin|dentine of tooth Collagen-rich odontogenic tissue characteristic of teeth and tooth-like skeletal elements (e.g., odontodes); mature dentine is mineralized and develops from predentine tissue; often (but not always) tubular and acellular. GO:0000405 bubble DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000405 Interacting selectively and non-covalently with DNA that contains a bubble. A bubble occurs when DNA contains a region of unpaired, single-stranded DNA flanked on both sides by regions of paired, double-stranded DNA. GO:0000404 heteroduplex DNA loop binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000404 loop DNA binding Interacting selectively and non-covalently with DNA containing a loop. A loop occurs when DNA contains a large insertion or deletion that causes a region of unpaired single-stranded DNA to loop out, while the rest of the DNA is in a paired double-stranded configuration. GO:0000403 Y-form DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000403 forked DNA binding|splayed Y-form DNA binding Interacting selectively and non-covalently with segment of DNA shaped like a Y. This shape occurs when DNA contains a region of paired double-stranded DNA on one end and a region of unpaired DNA strands on the opposite end. GO:0000409 regulation of transcription by galactose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000409 Any process involving galactose that modulates the frequency, rate or extent or transcription. UBERON:0001750 lacrimal apparatus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001750 apparatus lacrimalis|lacrimal drainage system|lacrymal system|nasolacrimal system|nasolacrimal drainage system A network of orbital structures of the eye that secrete and drain tears from the surface of the eyeball into the nasal cavity; these parts include the lacrimal glands, lacrimal lake, lacrimal ducts, lacrimal canals, lacrimal sacs, nasolacrimal ducts, and lacrimal puncta. GO:0000408 EKC/KEOPS complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000408 KEOPS/EKC complex|endopeptidase-like kinase chromatin-associated protein complex|threonyl-carbamoly transferase complex|TCTC|kinase, putative endopeptidase and other proteins of small size protein complex A protein complex involved in t6A tRNA modification. For example, in Saccharomyces cerevisiae the complex contains Bud32p, Kae1p, Gon7p, Cgi121p, and Pcc1p. GO:0000407 phagophore assembly site biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000407 pre-autophagosomal structure|perivacuolar space|PAS Punctate structures proximal to the endoplasmic reticulum which are the sites where the Atg machinery assembles upon autophagy induction. UBERON:0001737 larynx biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001737 Kehlkopf@de A continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration. UBERON:0001739 laryngeal cartilage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001739 larynx cartilage|cartilage of larynx|cartilagines laryngeales The cartilaginous structures that support the larynx. GO:0000413 protein peptidyl-prolyl isomerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000413 protein proline isomerization The modification of a protein by cis-trans isomerization of a proline residue. GO:0000412 histone peptidyl-prolyl isomerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000412 histone proline isomerization The modification of a histone by cis-trans isomerization of a proline residue. UBERON:0001733 soft palate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001733 velum palatinum|muscular palate|velum|palatum molle The muscular, non-bony arch-shaped posterior portion of the palate extending from the posterior edge of the hard palate. UBERON:0001736 submandibular gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001736 mandibular gland|maxillary gland|submaxillary gland|glandula submandibularis|submandibular salivary gland|mandibular salivary gland Either of the paired compound tubuloalveolar (aka tubuloacinar) major salivary glands composed of both serous and mucous secretory cells and situated beneath the mandible. GO:0000411 positive regulation of transcription by galactose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000411 up regulation of transcription by galactose|upregulation of transcription by galactose|stimulation of transcription by galactose|activation of transcription by galactose|up-regulation of transcription by galactose Any process involving galactose that activates or increases the rate of transcription. GO:0000410 carbon catabolite repression of transcription by galactose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000410 down-regulation of transcription by galactose|downregulation of transcription by galactose|down regulation of transcription by galactose|inhibition of transcription by galactose A transcription regulation process in which the presence of galactose that leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances. CHEBI:48360 amphiprotic solvent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48360 CHEBI:48362 but-1-ene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48362 CHEBI:48361 butene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48361 CHEBI:63947 2,2'-disulfoazobenzene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63947 CHEBI:63944 macrocyclic lactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63944 GO:0000417 HIR complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000417 HIRA complex A protein complex proposed to be involved in replication-independent nucleosome assembly, by promoting histone deposition onto DNA. For example, in Saccharomyces, the complex contains Hir1p, Hir2p, Hir3p, and Hpc2p. GO:0000416 positive regulation of histone H3-K36 methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000416 stimulation of histone H3-K36 methylation|up-regulation of histone H3-K36 methylation|activation of histone H3-K36 methylation|up regulation of histone H3-K36 methylation|upregulation of histone H3-K36 methylation Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 36 of histone H3. UBERON:0001743 ligament of larynx biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001743 laryngeal ligament|larynx ligament A ligament that is part of a larynx and connexts the cartilages of the larynx GO:0000415 negative regulation of histone H3-K36 methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000415 down-regulation of histone H3-K36 methylation|downregulation of histone H3-K36 methylation|down regulation of histone H3-K36 methylation|inhibition of histone H3-K36 methylation Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 36 of histone H3. GO:0000414 regulation of histone H3-K36 methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000414 Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 36 of histone H3. GO:0000419 RNA polymerase V complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000419 DNA-directed RNA polymerase V complex|DNA-directed RNA polymerase IVb complex RNA polymerase V is a multisubunit RNA polymerase complex found in the nucleus of plants and involved in accumulation of siRNAs and in DNA methylation-dependent silencing of endogenous repeated sequences. Pol V is composed of subunits that are paralogous or identical to the 12 subunits of Pol II. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The second largest subunit is also found in RNA polymerase IVa, while the largest subunit is found only in the IVa complex and contains an extended C-terminal domain (CTD) that includes multiple repeats of a 16 amino-acid consensus sequence as well as other sequences. The remainder of the complex is composed of smaller subunits. GO:0000418 RNA polymerase IV complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000418 DNA-directed RNA polymerase IVa complex|DNA-directed RNA polymerase IV complex RNA polymerase IV is a multisubunit RNA polymerase complex found in the nucleus of plants and involved in accumulation of siRNAs and in DNA methylation-dependent silencing of endogenous repeated sequences. Pol IV is composed of subunits that are paralogous or identical to the 12 subunits of Pol II. The largest and second-largest subunits of Pol IV are the catalytic subunits and share similarity with the corresponding subunits of other eukaryotic and bacterial multisubunit RNA polymerases. The second largest subunit is also found in RNA polymerase V, while the largest subunit is found only in RNAP IV complex. UBERON:0001727 taste bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001727 tastebuds|taste buds|caliculus gustatorius|tastebud|taste-bud A specialized receptor organ that is a collection of cells spanning the gustatory epithelium. GO:0097376 interneuron axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097376 The process in which the migration of an axon growth cone of an interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. An interneuron is any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region, as contrasted with projection neurons which have axons projecting to other brain regions. CHEBI:48357 aprotic solvent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48357 GO:0097375 spinal sensory neuron axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097375 The process in which the migration of an axon growth cone of a spinal sensory neuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A spinal sensory neuron is a sensory neuron that project to the spinal cord. UBERON:0001726 papilla of tongue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001726 lingual papilla|tongue papilla CHEBI:48356 protic solvent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48356 GO:0097378 dorsal spinal cord interneuron axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097378 dorsal interneuron axon guidance The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A dorsal spinal cord interneuron is an interneuron located in the dorsal part of the spinal cord. CHEBI:48359 protophilic solvent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48359 UBERON:0001728 nasopharynx biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001728 nasal part of pharynx|Nasenrachenraum|rhinopharynx|epipharynx|pars nasalis pharyngis the section of the pharynx that lies above the soft palate GO:0097377 spinal cord interneuron axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097377 The process in which the migration of an axon growth cone of a spinal cord interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A spinal cord interneuron is a CNS interneuron located in the spinal cord. CHEBI:48358 polar aprotic solvent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48358 CHEBI:24387 glycolaldehydes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24387 GO:0097372 NAD-dependent histone deacetylase activity (H3-K18 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097372 Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 18) + H2O = histone H3 L-lysine (position 18) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 18 of the histone H3 protein. UBERON:0001723 tongue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001723 glossus A muscular organ in the floor of the mouth. GO:0097371 MDM2/MDM4 family protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097371 Interacting selectively and non-covalently with any isoform of the MDM2/MDM4 protein family, comprising negative regulators of p53. UBERON_CORE:distally_connected_to distally connected to biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/uberon/core#distally_connected_to distally_connected_to x distally_connected_to y iff the distal part of x is connected to y. i.e. x connected_to y and x proximal_to y. GO:0097374 sensory neuron axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097374 The process in which the migration of an axon growth cone of a sensory neuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A sensory neuron is an afferent neuron conveying sensory impulses. UBERON:0001725 cranial synchondrosis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001725 The cartilaginous joints of the skull; these include sphenoethmoidal synchondrosis, sphenooccipital synchondrosis, sphenopetrosal synchondrosis, petrooccipital synchondrosis, anterior intraoccipital synchondrosis and posterior intraoccipital synchondrosis. GO:0097373 MCM core complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097373 MCM4/6/7 complex A protein complex that contains Mcm4, Mcm6, and Mcm7 proteins, and possesses DNA helicase activity. In the heterohexameric MCM complex, the Mcm4/6/7 proteins form a stable core, and Mcm2, Mcm3, and Mcm5 are more peripherally associated. GO:0097370 protein O-GlcNAcylation via threonine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097370 The glycosylation of a protein by addition of N-acetylglucosamine via the O3 atom of peptidyl-threonine, forming O3-N-acetylglucosamine-L-threonine. CHEBI:63950 2,2'-disulfonatoazobenzene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63950 CHEBI:48353 serine proteinase inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48353 CHEBI:24385 glycoglycerolipid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24385 CHEBI:24384 glycogens biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24384 CHEBI:48355 non-polar solvent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48355 CHEBI:48354 polar solvent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48354 CHEBI:63954 ionomycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63954 CHEBI:63953 2-amino-6-chloro-4-(3-sulfoanilino)-1,3,5-triazine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63953 CHEBI:63951 estrogen receptor agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63951 CHEBI:63955 2-amino-6-chloro-4-(3-sulfonatoanilino)-1,3,5-triazine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63955 UBERON:0001731 cavity of pharynx biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001731 cavitas pharyngealis|pharyngeal cavity|lumen of pharynx|cavitas pharyngis A anatomical space that is enclosed by a pharynx. GO:0097379 dorsal spinal cord interneuron posterior axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097379 dorsal interneuron caudal axon projection The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in the posterior direction along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism. UBERON:0001716 secondary palate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001716 roof of mouth|palatum|palatum definitivum|palatum secundarium|palatum|definitive palate|palate|oral roof The part of the palate formed from the fusion of the two palatine shelves, extensions of the maxillary prominences. GO:0097387 capitate projection biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097387 Simple or compound process of epithelial glial cells with a spherical head that inserts into photoreceptor axons. Capitate projections have only been observed in Brachycera (flies). UBERON:0001715 oculomotor nuclear complex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001715 oculomotor nucleus|nucleus oculomotorius|nucleus of oculomotor nuclear complex|OM|third cranial nerve nucleus|nucleus of oculomotor nerve|nIII|nucleus nervi oculomotorii|oculomotor III nuclear complex|nucleus of third cranial nerve|oculomotor III nucleus|motor nucleus III|oculomotor motornucleus Nuclear complex containing subnuclei that give rise to the axons of the occulomotor nerve, both motor and parasympathetic fibers, situated at the midline at the level of the superior colliculus in the midbrain tegmentum (Brodal, Neurological Anatomy, 3rd ed., 1981, pg 533-534). GO:0097386 glial cell projection biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097386 glial projection|glial process A prolongation or process extending from a glial cell. CHEBI:48345 pyrazinecarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48345 UBERON:0001718 mesencephalic nucleus of trigeminal nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001718 trigeminal nerve mesencepahlic nucleus|mesencephalic trigeminal nucleus|trigeminal V mesencephalic nucleus|nucleus mesencephalicus nervi trigemini|mesencephalic nucleus of the trigeminal|mesencephalic trigeminal V nucleus|nucleus mesencephalicus nervi trigeminalis|mesencephalic nuclei of trigeminal nerves|midbrain trigeminal nucleus|nucleus of mesencephalic root of v|Me5|nucleus tractus mesencephalicus nervi trigemini|mesencephalic nucleus|trigeminal mesencephalic nucleus|nucleus tractus mesencephalici nervi trigemini|mesencephalic nucleus of the trigeminal nerve Elongated nucleus located in the midbrain tegmentum that receives proprioceptive input from both teh extraocular and the masticatory muscles. Contrary to the general rule, the cell bodies that give rise to these sensory fibers are located within the mesencephalic nucleus rather than in a peripheral ganglion. Some of the sensory fibers in the mesencephalic root give off collaterals to the trigeminal motor nucleus, thereby providing the anatomic basis for the monosynaptic jaw reflex. (Heimer, L. The Human Brain and Spinal Cord, 2nd ed. 1996, page 248). GO:0097389 chemokine (C-C motif) ligand 21 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0097389 CCL21 production The appearance of chemokine (C-C motif) ligand 21 (CCL21) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. CHEBI:24399 glycosaminyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24399 UBERON:0001717 spinal nucleus of trigeminal nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001717 trigeminal spinal sensory nucleus|spinal trigeminal nucleus|trigeminal nerve spinal tract nucleus|trigeminal v spinal sensory nucleus|spinal nucleus of cranial nerve v|nucleus spinalis nervi trigemini|trigeminal spinal nucleus|spinal nucleus of the trigeminal Nucleus extending from the upper spinal cord through the pontine tegmentum that receives sensory inputs from the trigeminal nerve. It is continuous caudally with the dorsal gray matter of the spinal cord. GO:0097388 chemokine (C-C motif) ligand 19 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0097388 CCL19 production|ELC production|EBI1 ligand chemokine production|macrophage inflammatory protein-3-beta production|MIP-3-beta production The appearance of chemokine (C-C motif) ligand 19 (CCL19) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0097383 dIDP diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097383 RHEA:35211|Reactome:R-HSA-2509793 deoxyinosine-diphosphatase activity Catalysis of the reaction: dIDP + H2O = dIMP + phosphate. UBERON:0001711 eyelid biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001711 blepharon|palpebra|palpebrae|eye lid|blephara A fold of skin that covers and protects part of the eyeball. Examples: upper eyelid, lower eyelid, nictitating membrane GO:0097382 deoxynucleoside-diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097382 Catalysis of the reaction: a deoxynucleoside diphosphate + H2O = a deoxynucleotide + phosphate. UBERON:0001714 cranial ganglion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001714 cranial ganglia|cranial ganglion part of peripheral nervous system|cranial ganglion|cranial ganglion/nerve|ganglion of cranial neural tree organ|presumptive cranial ganglia|cranial nerve ganglion|head ganglion|ganglion of cranial nerve|cranial neural ganglion|cranial neural tree organ ganglion the groups of nerve cell bodies associated with the twelve cranial nerves GO:0097385 programmed necrotic cell death in response to starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097385 necrotic cell death in response to starvation A programmed necrotic cell death occurring as a result of a starvation stimulus (deprivation of nourishment). GO:0097384 cellular lipid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097384 cellular lipid synthesis|cellular lipid formation|cellular lipid biosynthesis|cellular lipid anabolism The chemical reactions and pathways resulting in the formation of lipids, as carried out by individual cells. GO:0097381 photoreceptor disc membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097381 Stack of disc membranes located inside a photoreceptor outer segment, and containing densely packed molecules of photoreceptor proteins that traverse the lipid bilayer. Disc membranes arise as evaginations of the ciliary membrane during the development of the outer segment and may or may not remain contiguous with the ciliary membrane. GO:0097380 dorsal spinal cord interneuron anterior axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097380 dorsal interneuron rostral axon projection The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in the anterior direction along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism. CHEBI:24397 glycophospholipid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24397 UBERON:0001719 nucleus ambiguus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001719 ambiguous nucleus|ambiguus nucleus|Amb|nucleus innominatus A region of histologically disparate cells located just dorsal to the inferior olivary nucleus in the lateral portion of the upper medulla. It receives upper motor neuron innervation directly via the corticobulbar tract This nucleus gives rise to the efferent motor fibers of the vagus nerve terminating in the laryngeal and pharyngeal muscles, as well as to the efferent motor fibers of the glossopharyngeal nerve (CN IX) terminating in the stylopharyngeus. [WP,unvetted]. CHEBI:24396 glycopeptide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24396 CHEBI:48343 disulfide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48343 CHEBI:63962 Hsp90 inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63962 CHEBI:63969 (5Z,8Z,14Z)-11,12-dihydroxyicosatrienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63969 CHEBI:63966 (5Z,8Z,11Z)-14,15-dihydroxyicosatrienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63966 UBERON:0001720 cochlear nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001720 cochlear VIII nucleus|cochlear nucleus of acoustic nerve|statoacoustic (VIII) nucleus|nucleus of cochlear nerve|vestibulocochlear nucleus|cochlear nucleus of eighth cranial nerve Any of the nuclei of the cochlear nuclear complex. GO:0048343 paraxial mesodermal cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048343 The process in which a cell becomes committed to become a paraxial mesoderm cell. GO:0048342 paraxial mesodermal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048342 The process in which a relatively unspecialized cell acquires the specialized features of a paraxial mesoderm cell. GO:0048341 paraxial mesoderm formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048341 The process that gives rise to the paraxial mesoderm. This process pertains to the initial formation of the structure from unspecified parts. GO:0048340 paraxial mesoderm morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048340 The process in which the anatomical structures of the paraxial mesoderm are generated and organized. GO:1903749 positive regulation of establishment of protein localization to mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903749 up regulation of establishment of protein localization in mitochondrion|up-regulation of establishment of protein localisation to mitochondrion|activation of establishment of protein localisation to mitochondrion|upregulation of establishment of protein localization in mitochondrion|up regulation of establishment of protein localization to mitochondrion|positive regulation of establishment of protein localisation to mitochondrion|up regulation of establishment of protein localisation to mitochondrion|up-regulation of establishment of protein localization in mitochondrion|upregulation of establishment of protein localization to mitochondrion|activation of establishment of protein localization in mitochondrion|upregulation of establishment of protein localisation to mitochondrion|up-regulation of establishment of protein localization to mitochondrion|positive regulation of establishment of protein localization in mitochondrion|activation of establishment of protein localization to mitochondrion Any process that activates or increases the frequency, rate or extent of establishment of protein localization to mitochondrion. GO:1903748 negative regulation of establishment of protein localization to mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903748 downregulation of establishment of protein localization in mitochondrion|down-regulation of establishment of protein localization to mitochondrion|down regulation of establishment of protein localization in mitochondrion|inhibition of establishment of protein localization in mitochondrion|negative regulation of establishment of protein localisation to mitochondrion|down-regulation of establishment of protein localisation to mitochondrion|downregulation of establishment of protein localization to mitochondrion|down regulation of establishment of protein localization to mitochondrion|inhibition of establishment of protein localization to mitochondrion|downregulation of establishment of protein localisation to mitochondrion|down regulation of establishment of protein localisation to mitochondrion|inhibition of establishment of protein localisation to mitochondrion|down-regulation of establishment of protein localization in mitochondrion|negative regulation of establishment of protein localization in mitochondrion Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization to mitochondrion. GO:1903747 regulation of establishment of protein localization to mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903747 regulation of establishment of protein localization in mitochondrion|regulation of establishment of protein localisation to mitochondrion Any process that modulates the frequency, rate or extent of establishment of protein localization to mitochondrion. GO:1903746 positive regulation of pharyngeal pumping biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903746 up-regulation of pharyngeal pumping|activation of pharyngeal pumping|upregulation of pumping behavior|up regulation of pharyngeal pumping|up-regulation of pumping behavior|activation of pumping behavior|upregulation of pharyngeal pumping|positive regulation of pumping behavior|up regulation of pumping behavior Any process that activates or increases the frequency, rate or extent of pharyngeal pumping. GO:1903745 negative regulation of pharyngeal pumping biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903745 down regulation of pumping behavior|down-regulation of pharyngeal pumping|inhibition of pumping behavior|downregulation of pharyngeal pumping|down regulation of pharyngeal pumping|negative regulation of pumping behavior|down-regulation of pumping behavior|inhibition of pharyngeal pumping|downregulation of pumping behavior Any process that stops, prevents or reduces the frequency, rate or extent of pharyngeal pumping. GO:0048349 regulation of paraxial mesodermal cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048349 Any process that modulates the frequency, rate or extent of paraxial mesoderm cell fate specification. GO:1903744 positive regulation of anterograde synaptic vesicle transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903744 up-regulation of anterograde synaptic vesicle transport|activation of anterograde synaptic vesicle transport|up regulation of anterograde synaptic vesicle transport|upregulation of anterograde synaptic vesicle transport Any process that activates or increases the frequency, rate or extent of anterograde synaptic vesicle transport. GO:1903743 negative regulation of anterograde synaptic vesicle transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903743 down-regulation of anterograde synaptic vesicle transport|downregulation of anterograde synaptic vesicle transport|down regulation of anterograde synaptic vesicle transport|inhibition of anterograde synaptic vesicle transport Any process that stops, prevents or reduces the frequency, rate or extent of anterograde synaptic vesicle transport. GO:0048348 paraxial mesodermal cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048348 The process in which a cell becomes capable of differentiating autonomously into a paraxial mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. GO:1903742 regulation of anterograde synaptic vesicle transport biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_1903742 Any process that modulates the frequency, rate or extent of anterograde synaptic vesicle transport. GO:0048347 negative regulation of paraxial mesodermal cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048347 down-regulation of paraxial mesodermal cell fate determination|inhibition of paraxial mesodermal cell fate determination|down regulation of paraxial mesodermal cell fate determination|downregulation of paraxial mesodermal cell fate determination Any process that stops, prevents, or reduces the frequency, rate or extent of paraxial mesoderm cell fate determination. GO:1903741 negative regulation of phosphatidate phosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903741 down regulation of phosphatidate phosphatase activity|inhibition of phosphatidate phosphatase activity|down-regulation of phosphatidic acid phosphatase activity|downregulation of 3-sn-phosphatidate phosphohydrolase activity|negative regulation of phosphatidic acid phosphatase activity|downregulation of acid phosphatidyl phosphatase activity|inhibition of phosphatidate phosphohydrolase activity|down regulation of phosphatic acid phosphohydrolase activity|downregulation of phosphatic acid phosphatase activity|down regulation of 3-sn-phosphatidate phosphohydrolase activity|down regulation of acid phosphatidyl phosphatase activity|inhibition of acid phosphatidyl phosphatase activity|inhibition of 3-sn-phosphatidate phosphohydrolase activity|downregulation of phosphatic acid phosphohydrolase activity|down regulation of phosphatic acid phosphatase activity|inhibition of phosphatic acid phosphatase activity|downregulation of phosphatidic acid phosphatase activity|down regulation of phosphatidic acid phosphatase activity|down regulation of phosphatidate phosphohydrolase activity|inhibition of phosphatidic acid phosphatase activity|negative regulation of phosphatic acid phosphohydrolase activity|down-regulation of phosphatic acid phosphohydrolase activity|down-regulation of phosphatidate phosphatase activity|downregulation of phosphatidate phosphohydrolase activity|inhibition of phosphatic acid phosphohydrolase activity|down-regulation of acid phosphatidyl phosphatase activity|down-regulation of 3-sn-phosphatidate phosphohydrolase activity|negative regulation of 3-sn-phosphatidate phosphohydrolase activity|negative regulation of acid phosphatidyl phosphatase activity|downregulation of phosphatidate phosphatase activity|negative regulation of phosphatic acid phosphatase activity|negative regulation of phosphatidate phosphohydrolase activity|down-regulation of phosphatic acid phosphatase activity|down-regulation of phosphatidate phosphohydrolase activity Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidate phosphatase activity. GO:0048346 positive regulation of paraxial mesodermal cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048346 up regulation of paraxial mesodermal cell fate determination|activation of paraxial mesodermal cell fate determination|stimulation of paraxial mesodermal cell fate determination|up-regulation of paraxial mesodermal cell fate determination|upregulation of paraxial mesodermal cell fate determination Any process that activates or increases the frequency, rate or extent of paraxial mesoderm cell fate determination. GO:1903740 positive regulation of phosphatidate phosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903740 up regulation of 3-sn-phosphatidate phosphohydrolase activity|up regulation of acid phosphatidyl phosphatase activity|positive regulation of phosphatic acid phosphatase activity|upregulation of phosphatidate phosphatase activity|upregulation of phosphatic acid phosphohydrolase activity|up regulation of phosphatic acid phosphatase activity|up-regulation of phosphatidate phosphohydrolase activity|positive regulation of phosphatidic acid phosphatase activity|up regulation of phosphatidic acid phosphatase activity|upregulation of acid phosphatidyl phosphatase activity|upregulation of 3-sn-phosphatidate phosphohydrolase activity|up-regulation of phosphatidate phosphatase activity|up regulation of phosphatic acid phosphohydrolase activity|activation of phosphatidate phosphatase activity|positive regulation of phosphatic acid phosphohydrolase activity|upregulation of phosphatic acid phosphatase activity|upregulation of phosphatidate phosphohydrolase activity|activation of phosphatic acid phosphohydrolase activity|up-regulation of acid phosphatidyl phosphatase activity|upregulation of phosphatidic acid phosphatase activity|up-regulation of 3-sn-phosphatidate phosphohydrolase activity|activation of 3-sn-phosphatidate phosphohydrolase activity|activation of acid phosphatidyl phosphatase activity|up-regulation of phosphatic acid phosphatase activity|up regulation of phosphatidate phosphohydrolase activity|activation of phosphatic acid phosphatase activity|up regulation of phosphatidate phosphatase activity|up-regulation of phosphatic acid phosphohydrolase activity|positive regulation of phosphatidate phosphohydrolase activity|activation of phosphatidate phosphohydrolase activity|up-regulation of phosphatidic acid phosphatase activity|activation of phosphatidic acid phosphatase activity|positive regulation of 3-sn-phosphatidate phosphohydrolase activity|positive regulation of acid phosphatidyl phosphatase activity Any process that activates or increases the frequency, rate or extent of phosphatidate phosphatase activity. GO:0048345 regulation of paraxial mesodermal cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048345 Any process that modulates the frequency, rate or extent of paraxial mesoderm cell fate determination. GO:0048344 paraxial mesodermal cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048344 The process in which a cell becomes capable of differentiating autonomously into a paraxial mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed. GO:0048354 mucilage biosynthetic process involved in seed coat development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048354 mucilage formation during seed coat development|mucilage synthesis during seed coat development|mucilage anabolism during seed coat development|mucilage biosynthetic process during seed coat development The chemical reactions and pathways resulting in the formation of mucilage that occur as part of seed coat development; mucilage is normally synthesized during seed coat development. GO:0048353 primary endosperm nucleus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0048353 Nucleus resulting from the fusion of the male gamete and two polar nuclei in the central cell of the embryo sac. GO:0048352 paraxial mesoderm structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048352 paraxial mesoderm structural organisation The process that contributes to the act of creating the structural organization of the paraxial mesoderm. This process pertains to the physical shaping of a rudimentary structure. GO:0048351 negative regulation of paraxial mesodermal cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048351 down regulation of paraxial mesodermal cell fate specification|downregulation of paraxial mesodermal cell fate specification|down-regulation of paraxial mesodermal cell fate specification|inhibition of paraxial mesodermal cell fate specification Any process that stops, prevents, or reduces the frequency, rate or extent of paraxial mesoderm cell fate specification. GO:0048350 positive regulation of paraxial mesodermal cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048350 upregulation of paraxial mesodermal cell fate specification|up regulation of paraxial mesodermal cell fate specification|activation of paraxial mesodermal cell fate specification|stimulation of paraxial mesodermal cell fate specification|up-regulation of paraxial mesodermal cell fate specification Any process that activates or increases the frequency, rate or extent of paraxial mesoderm cell fate specification. GO:1903759 obsolete signal transduction involved in regulation of aerobic respiration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903759 signaling cascade involved in regulation of aerobic respiration|signalling pathway involved in regulation of aerobic respiration|signaling pathway involved in regulation of aerobic respiration|signalling cascade involved in regulation of aerobic respiration OBSOLETE. Any signal transduction that is involved in regulation of aerobic respiration. GO:1903758 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1903758 GO:1903757 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1903757 GO:1903756 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1903756 GO:1903755 positive regulation of SUMO transferase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903755 positive regulation of SMT3 conjugating enzyme|upregulation of SUMO conjugating enzyme activity|activation of SMT3 conjugating enzyme|up regulation of SUMO transferase activity|activation of SUMO transferase activity|up-regulation of SUMO conjugating enzyme activity|up-regulation of SMT3 conjugating enzyme|activation of SUMO conjugating enzyme activity|upregulation of SMT3 conjugating enzyme|up-regulation of SUMO transferase activity|positive regulation of SUMO conjugating enzyme activity|up regulation of SUMO conjugating enzyme activity|up regulation of SMT3 conjugating enzyme|upregulation of SUMO transferase activity Any process that activates or increases the frequency, rate or extent of SUMO transferase activity. GO:1903754 cortical microtubule plus-end biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1903754 cortical microtubule plus end The plus-end of a cortical microtubule. GO:0048359 mucilage metabolic process involved in seed coat development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048359 mucilage metabolism during seed coat development|mucilage metabolic process during seed coat development The chemical reactions and pathways involving mucilage that occur as part of seed coat development; mucilage is normally synthesized during seed coat development. GO:0048358 mucilage pectin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048358 mucilage pectin biosynthesis|mucilage pectin anabolism|mucilage pectin synthesis|mucilage pectin formation The chemical reactions and pathways resulting in the formation of the pectin component of mucilage. GO:1903753 negative regulation of p38MAPK cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903753 negative regulation of p38 MAPK cascade|down-regulation of p38 MAPK cascade|down-regulation of p38 cascade|negative regulation of p38 cascade|down regulation of p38MAPK cascade|inhibition of p38 cascade|downregulation of p38MAPK cascade|downregulation of p38 MAPK cascade|down regulation of p38 MAPK cascade|inhibition of p38 MAPK cascade|down-regulation of p38MAPK cascade|down regulation of p38 cascade|inhibition of p38MAPK cascade|downregulation of p38 cascade Any process that stops, prevents or reduces the frequency, rate or extent of p38MAPK cascade. GO:1903752 positive regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903752 activation of H2O2-induced intrinsic apoptotic signaling pathway|up regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide|positive regulation of H2O2-induced intrinsic apoptotic signaling pathway|upregulation of intrinsic apoptotic signaling pathway in response to H2O2|up regulation of H2O2-induced intrinsic apoptotic signaling pathway|up-regulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|upregulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide|up regulation of intrinsic apoptotic signaling pathway in response to H2O2|upregulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|upregulation of H2O2-induced intrinsic apoptotic signaling pathway|activation of intrinsic apoptotic signaling pathway in response to H2O2|positive regulation of intrinsic apoptotic signaling pathway in response to H2O2|up-regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide|activation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide|up-regulation of H2O2-induced intrinsic apoptotic signaling pathway|up regulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|activation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|up-regulation of intrinsic apoptotic signaling pathway in response to H2O2|positive regulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to hydrogen peroxide. GO:0048357 pedicel mucilage biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048357 pedicel mucilage formation|pedicel mucilage biosynthesis|pedicel mucilage anabolism|pedicel mucilage synthesis The chemical reactions and pathways resulting in the formation of mucilage that occur in the flower stem. GO:0048356 root epithelial mucilage biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048356 root epithelial mucilage biosynthesis|root epithelial mucilage anabolism|root epithelial mucilage synthesis|root epithelial mucilage formation The chemical reactions and pathways resulting in the formation of mucilage that occur in the root epithelium; mucilage is normally synthesized during root growth. GO:1903751 negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903751 negative regulation of H2O2-induced intrinsic apoptotic signaling pathway|down-regulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|down-regulation of H2O2-induced intrinsic apoptotic signaling pathway|negative regulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|downregulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide|inhibition of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|down regulation of intrinsic apoptotic signaling pathway in response to H2O2|down regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide|downregulation of H2O2-induced intrinsic apoptotic signaling pathway|inhibition of intrinsic apoptotic signaling pathway in response to hydrogen peroxide|downregulation of intrinsic apoptotic signaling pathway in response to H2O2|down regulation of H2O2-induced intrinsic apoptotic signaling pathway|down regulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|inhibition of H2O2-induced intrinsic apoptotic signaling pathway|negative regulation of intrinsic apoptotic signaling pathway in response to H2O2|down-regulation of intrinsic apoptotic signaling pathway in response to H2O2|downregulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|inhibition of intrinsic apoptotic signaling pathway in response to H2O2|down-regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to hydrogen peroxide. GO:0048355 root cap mucilage biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048355 root cap mucilage synthesis|root cap mucilage biosynthesis|root cap mucilage formation|root cap mucilage anabolism The chemical reactions and pathways resulting in the formation of mucilage that occur in the root cap; mucilage is normally synthesized during root growth. GO:1903750 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903750 regulation of intrinsic apoptotic signaling pathway in response to H2O2|regulation of H2O2-induced intrinsic apoptotic signaling pathway|regulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|regulation of hydrogen peroxide-induced apoptosis Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to hydrogen peroxide. GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903760 regulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|regulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|regulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|regulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential Any process that modulates the frequency, rate or extent of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization. GO:0000387 spliceosomal snRNP assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000387 spliceosomal snRNP biogenesis The aggregation, arrangement and bonding together of one or more snRNA and multiple protein components to form a ribonucleoprotein complex that is involved in formation of the spliceosome. GO:0048365 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048365 GO:0048364 root development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048364 The process whose specific outcome is the progression of the root over time, from its formation to the mature structure. The root is the water- and mineral-absorbing part of a plant which is usually underground, does not bear leaves, tends to grow downwards and is typically derived from the radicle of the embryo. GO:0000386 second spliceosomal transesterification activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000386 lariat formation, 5'-splice site cleavage|3'-splice site cleavage, exon ligation Catalysis of the second transesterification reaction of spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure. GO:0048363 mucilage pectin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048363 mucilage pectin metabolism The chemical reactions and pathways involving the pectin component of mucilage. GO:0000385 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000385 GO:0048362 pedicel mucilage metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048362 pedicel mucilage metabolism The chemical reactions and pathways involving mucilage that occur in the flower stem. GO:0000384 first spliceosomal transesterification activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000384 lariat formation, 5'-splice site cleavage Catalysis of the first transesterification reaction of spliceosomal mRNA splicing. The intron branch site adenosine is the nucleophile attacking the 5' splice site, resulting in cleavage at this position. In cis splicing, this is the step that forms a lariat structure of the intron RNA, while it is still joined to the 3' exon. GO:0048361 root epithelial mucilage metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048361 root epithelial mucilage metabolism The chemical reactions and pathways involving mucilage that occur in the root epithelium; mucilage is normally synthesized during root growth. GO:0048360 root cap mucilage metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048360 root cap mucilage metabolism The chemical reactions and pathways involving mucilage that occur in the root cap; mucilage is normally synthesized during root growth. GO:0000389 mRNA 3'-splice site recognition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000389 U12-type nuclear mRNA 3'-splice site recognition|nuclear mRNA 3'-splice site recognition|U2-type nuclear mRNA 3'-splice site recognition Recognition of the intron 3'-splice site by components of the assembling U2- or U12-type spliceosome. GO:0000388 spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000388 U12-type spliceosome conformational change to release U4atac and U11|spliceosomal A1 complex formation|spliceosomal B2 complex formation|U2-type spliceosome conformational change to release U4 and U1|3'-splice site cleavage, exon ligation|spliceosomal A1 complex biosynthesis|spliceosomal B2 complex biosynthesis Rearrangement of the pre-catalytic spliceosome containing U4 (or U4atac) and U1 (or U11) snRNPs to unpair U4 (or U4atac) from U6 (or U6atac) and release it from the spliceosomal complex along with U1 (or U11). GO:1903769 negative regulation of cell proliferation in bone marrow biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903769 down regulation of cell proliferation in bone marrow|downregulation of cell proliferation in bone marrow|down-regulation of bone marrow cell proliferation|negative regulation of bone marrow cell proliferation|down-regulation of cell proliferation in bone marrow|downregulation of bone marrow cell proliferation|inhibition of cell proliferation in bone marrow|down regulation of bone marrow cell proliferation|inhibition of bone marrow cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in bone marrow. GO:1903768 taste receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1903768 A protein complex which is capable of taste receptor activity. GO:1903767 sweet taste receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1903767 A protein complex which is capable of sweet taste receptor activity. GO:1903766 positive regulation of potassium ion export across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903766 upregulation of potassium export|up regulation of potassium ion export across plasma membrane|upregulation of potassium ion export|activation of potassium export|up-regulation of potassium export|positive regulation of potassium ion export|activation of potassium ion export across plasma membrane|up-regulation of potassium ion export across plasma membrane|up-regulation of potassium ion export|activation of potassium ion export|positive regulation of potassium export|up regulation of potassium export|upregulation of potassium ion export across plasma membrane|up regulation of potassium ion export Any process that activates or increases the frequency, rate or extent of potassium ion export across the plasma membrane. GO:1903765 negative regulation of potassium ion export across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903765 downregulation of potassium ion export|down regulation of potassium ion export|inhibition of potassium ion export|down-regulation of potassium ion export across plasma membrane|negative regulation of potassium ion export|down-regulation of potassium export|negative regulation of potassium export|inhibition of potassium export|inhibition of potassium ion export across plasma membrane|down-regulation of potassium ion export|downregulation of potassium export|down regulation of potassium ion export across plasma membrane|down regulation of potassium export|downregulation of potassium ion export across plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion export across the plasma membrane. GO:1903764 regulation of potassium ion export across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903764 regulation of potassium export across plasma membrane|regulation of potassium ion export|regulation of potassium export Any process that modulates the frequency, rate or extent of potassium ion export across the plasma membrane. GO:0048369 lateral mesoderm morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048369 lateral plate mesoderm morphogenesis The process in which the anatomical structures of the lateral mesoderm are generated and organized. GO:0000383 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000383 GO:0048368 lateral mesoderm development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048368 lateral plate mesoderm development The process whose specific outcome is the progression of the lateral mesoderm over time, from its formation to the mature structure. GO:1903763 gap junction channel activity involved in cell communication by electrical coupling biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1903763 innexin channel activity involved in cell communication by electrical coupling|innexin involved in cell communication by electrical coupling|connexin involved in cell communication by electrical coupling Any gap junction channel activity that is involved in cell communication by electrical coupling. GO:0000382 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000382 GO:0000381 regulation of alternative mRNA splicing, via spliceosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000381 regulation of alternative nuclear mRNA splicing, via spliceosome|splice site selection Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs. GO:1903762 positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903762 up-regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization|activation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization|up-regulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|upregulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|upregulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|up regulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|upregulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|positive regulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|up regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization|activation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|up-regulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|activation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|up regulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|activation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|up regulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|positive regulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|up-regulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|positive regulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|activation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|upregulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization|positive regulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|up regulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|upregulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|up-regulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential Any process that activates or increases the frequency, rate or extent of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization. GO:0048367 shoot system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048367 shoot development The process whose specific outcome is the progression of the shoot system over time, from its formation to the mature structure. GO:1903761 negative regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903761 inhibition of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|down regulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|down regulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|inhibition of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|downregulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|down-regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization|down regulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|negative regulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|down-regulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|down regulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|downregulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|downregulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization|downregulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|down regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization|inhibition of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization|down-regulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|negative regulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|down-regulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|negative regulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|inhibition of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|down-regulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|negative regulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|inhibition of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|downregulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization. GO:0048366 leaf development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048366 The process whose specific outcome is the progression of the leaf over time, from its formation to the mature structure. GO:0000380 alternative mRNA splicing, via spliceosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000380 splice site selection|alternative nuclear mRNA splicing, via spliceosome The process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition. GO:1903771 positive regulation of beta-galactosidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903771 upregulation of lactose hydrolysis|upregulation of lactozym|activation of S 2107|activation of beta-D-lactosidase activity|positive regulation of beta-D-lactosidase activity|activation of sumiklat|up-regulation of beta-D-galactoside galactohydrolase activity|up-regulation of hydrolact|activation of beta-D-galactoside galactohydrolase activity|up-regulation of oryzatym|up-regulation of maxilact|upregulation of beta-galactosidase activity|up-regulation of beta-D-galactanase activity|positive regulation of S 2107|up-regulation of trilactase activity|positive regulation of sumiklat|up-regulation of exo-(1->4)-beta-D-galactanase activity|up regulation of beta-lactosidase activity|up regulation of S 2107|activation of exo-(1->4)-beta-D-galactanase activity|up-regulation of lactozym|up-regulation of lactose hydrolysis|activation of oryzatym|up regulation of sumiklat|activation of maxilact|activation of beta-lactosidase activity|positive regulation of beta-lactosidase activity|upregulation of hydrolact|up-regulation of beta-D-lactosidase activity|upregulation of beta-D-galactanase activity|positive regulation of beta-D-galactoside galactohydrolase activity|positive regulation of maxilact|up regulation of beta-galactosidase activity|positive regulation of oryzatym|activation of lactose hydrolysis|activation of lactozym|up regulation of beta-D-galactoside galactohydrolase activity|upregulation of trilactase activity|activation of beta-galactosidase activity|up regulation of oryzatym|up regulation of maxilact|positive regulation of exo-(1->4)-beta-D-galactanase activity|upregulation of S 2107|upregulation of sumiklat|positive regulation of lactozym|up regulation of exo-(1->4)-beta-D-galactanase activity|positive regulation of lactose hydrolysis|upregulation of beta-D-lactosidase activity|up regulation of hydrolact|up-regulation of beta-lactosidase activity|up regulation of lactozym|up regulation of lactose hydrolysis|up regulation of beta-D-galactanase activity|positive regulation of hydrolact|up regulation of trilactase activity|upregulation of beta-D-galactoside galactohydrolase activity|activation of beta-D-galactanase activity|positive regulation of beta-D-galactanase activity|upregulation of oryzatym|upregulation of maxilact|positive regulation of trilactase activity|up-regulation of S 2107|up-regulation of beta-galactosidase activity|activation of trilactase activity|up-regulation of sumiklat|activation of hydrolact|upregulation of beta-lactosidase activity|upregulation of exo-(1->4)-beta-D-galactanase activity|up regulation of beta-D-lactosidase activity Any process that activates or increases the frequency, rate or extent of beta-galactosidase activity. GO:1903770 negative regulation of beta-galactosidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903770 down regulation of beta-lactosidase activity|down-regulation of S 2107|negative regulation of S 2107|negative regulation of sumiklat|down-regulation of sumiklat|inhibition of beta-D-galactanase activity|inhibition of lactozym|inhibition of lactose hydrolysis|negative regulation of beta-D-lactosidase activity|downregulation of beta-lactosidase activity|down-regulation of beta-D-lactosidase activity|inhibition of trilactase activity|down regulation of beta-galactosidase activity|inhibition of hydrolact|negative regulation of beta-D-galactoside galactohydrolase activity|down-regulation of beta-D-galactoside galactohydrolase activity|negative regulation of maxilact|down-regulation of maxilact|down-regulation of oryzatym|negative regulation of oryzatym|downregulation of beta-galactosidase activity|downregulation of S 2107|inhibition of beta-D-lactosidase activity|downregulation of sumiklat|down-regulation of beta-lactosidase activity|negative regulation of exo-(1->4)-beta-D-galactanase activity|down regulation of hydrolact|down-regulation of exo-(1->4)-beta-D-galactanase activity|negative regulation of beta-lactosidase activity|down regulation of S 2107|down-regulation of lactose hydrolysis|negative regulation of lactozym|down-regulation of lactozym|down regulation of beta-D-galactanase activity|negative regulation of lactose hydrolysis|down regulation of sumiklat|downregulation of beta-D-galactoside galactohydrolase activity|down regulation of trilactase activity|downregulation of hydrolact|downregulation of maxilact|downregulation of oryzatym|downregulation of beta-D-galactanase activity|down-regulation of beta-galactosidase activity|inhibition of beta-lactosidase activity|inhibition of S 2107|downregulation of trilactase activity|down regulation of beta-D-galactoside galactohydrolase activity|inhibition of sumiklat|downregulation of exo-(1->4)-beta-D-galactanase activity|down regulation of maxilact|down regulation of oryzatym|down regulation of beta-D-lactosidase activity|inhibition of beta-D-galactoside galactohydrolase activity|downregulation of lactozym|downregulation of lactose hydrolysis|down-regulation of hydrolact|inhibition of beta-galactosidase activity|negative regulation of hydrolact|down regulation of exo-(1->4)-beta-D-galactanase activity|downregulation of beta-D-lactosidase activity|down regulation of lactose hydrolysis|negative regulation of beta-D-galactanase activity|inhibition of exo-(1->4)-beta-D-galactanase activity|down regulation of lactozym|down-regulation of beta-D-galactanase activity|inhibition of oryzatym|inhibition of maxilact|negative regulation of trilactase activity|down-regulation of trilactase activity Any process that stops, prevents or reduces the frequency, rate or extent of beta-galactosidase activity. GO:0048376 positive regulation of lateral mesodermal cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048376 upregulation of lateral mesodermal cell fate determination|stimulation of lateral mesodermal cell fate determination|up-regulation of lateral mesodermal cell fate determination|activation of lateral mesodermal cell fate determination|positive regulation of lateral plate mesodermal cell fate determination|up regulation of lateral mesodermal cell fate determination Any process that activates or increases the frequency, rate or extent of lateral mesoderm cell fate determination. GO:0000398 mRNA splicing, via spliceosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000398 splicing GT-AG intron|mRNA splicing|nuclear mRNA splicing, via spliceosome|nuclear mRNA splicing via U2-type spliceosome|pre-mRNA splicing|nuclear mRNA splicing via U12-type spliceosome|splicing AT-AC intron The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced. GO:0000397 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000397 GO:0048375 negative regulation of lateral mesodermal cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048375 negative regulation of lateral plate mesodermal cell fate determination|down-regulation of lateral mesodermal cell fate determination|downregulation of lateral mesodermal cell fate determination|down regulation of lateral mesodermal cell fate determination|inhibition of lateral mesodermal cell fate determination Any process that stops, prevents, or reduces the frequency, rate or extent of lateral mesoderm cell fate determination. GO:0000396 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000396 GO:0048374 regulation of lateral mesodermal cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048374 regulation of lateral mesoderm cell fate determination|regulation of lateral plate mesodermal cell fate determination|regulation of lateral plate mesoderm cell fate determination Any process that modulates the frequency, rate or extent of lateral mesoderm cell fate determination. GO:0048373 lateral mesodermal cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048373 lateral plate mesodermal cell fate determination|lateral plate mesoderm cell fate determination|lateral mesoderm cell fate determination The process in which a cell becomes capable of differentiating autonomously into a lateral mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed. GO:0000395 mRNA 5'-splice site recognition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000395 U2-type nuclear mRNA 5'-splice site recognition|nuclear mRNA 5' splice site recognition|spliceosomal CC complex formation|U12-type nuclear mRNA 5' splice site recognition|spliceosomal commitment complex biosynthesis|spliceosomal E complex formation|spliceosomal E complex biosynthesis|spliceosomal commitment complex formation|U2-type nuclear mRNA 5' splice site recognition|U12-type nuclear mRNA 5'-splice site recognition|spliceosomal CC complex biosynthesis|nuclear mRNA 5'-splice site recognition Recognition of the intron 5'-splice site by components of the assembling spliceosome. GO:0048372 lateral mesodermal cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048372 lateral plate mesodermal cell fate commitment|lateral mesoderm cell fate commitment|lateral plate mesoderm cell fate commitment The process in which a cell becomes committed to become a lateral mesoderm cell. GO:0048371 lateral mesodermal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048371 lateral plate mesodermal cell differentiation|lateral mesoderm cell differentiation|lateral plate mesoderm cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a lateral mesoderm cell. GO:0048370 lateral mesoderm formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048370 lateral plate mesoderm formation|lateral plate mesoderm biosynthesis The process that gives rise to the lateral mesoderm. This process pertains to the initial formation of the structure from unspecified parts. GO:0000399 cellular bud neck septin structure biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000399 Any of a series of septin structures that are localized in the bud neck of a budding fungal cell during the cell cycle. GO:0000390 spliceosomal complex disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000390 U12-type spliceosome disassembly|spliceosome disassembly|spliceosome complex disassembly|U2-type spliceosome disassembly Disassembly of a spliceosomal complex with the ATP-dependent release of the product RNAs, one of which is composed of the joined exons. In cis splicing, the other product is the excised sequence, often a single intron, in a lariat structure. GO:1903779 regulation of cardiac conduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903779 Any process that modulates the frequency, rate or extent of cardiac conduction. GO:1903778 protein localization to vacuolar membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903778 protein localisation in vacuolar membrane|protein localisation to vacuolar membrane|protein localization in vacuolar membrane A process in which a protein is transported to, or maintained in, a location within a vacuolar membrane. GO:1903777 melibiose binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1903777 Interacting selectively and non-covalently with melibiose. GO:1903776 regulation of double-strand break repair via single-strand annealing, removal of nonhomologous ends biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903776 Any process that modulates the frequency, rate or extent of double-strand break repair via single-strand annealing, removal of nonhomologous ends. GO:1903775 regulation of DNA double-strand break processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903775 Any process that modulates the frequency, rate or extent of DNA double-strand break processing. GO:0000394 RNA splicing, via endonucleolytic cleavage and ligation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000394 mRNA splicing Splicing of RNA via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons. GO:1903774 positive regulation of viral budding via host ESCRT complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903774 up-regulation of viral budding via host ESCRT complex|activation of viral budding via host ESCRT complex|up-regulation of viral budding through the ESCRT machinery|upregulation of viral budding through the ESCRT machinery|up regulation of viral budding via host ESCRT complex|up regulation of viral budding through the ESCRT machinery|upregulation of viral budding via host ESCRT complex|positive regulation of viral budding through the ESCRT machinery|activation of viral budding through the ESCRT machinery Any process that activates or increases the frequency, rate or extent of viral budding via host ESCRT complex. GO:0000393 spliceosomal conformational changes to generate catalytic conformation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000393 3'-splice site cleavage, exon ligation Structural rearrangements of the spliceosome complex, containing RNA to be spliced, to generate a catalytic conformation. GO:0048379 positive regulation of lateral mesodermal cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048379 upregulation of lateral mesodermal cell fate specification|stimulation of lateral mesodermal cell fate specification|up-regulation of lateral mesodermal cell fate specification|activation of lateral mesodermal cell fate specification|positive regulation of lateral plate mesodermal cell fate specification|up regulation of lateral mesodermal cell fate specification Any process that activates or increases the frequency, rate or extent of lateral mesoderm cell fate specification. GO:1903773 negative regulation of viral budding via host ESCRT complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903773 down-regulation of viral budding via host ESCRT complex|inhibition of viral budding through the ESCRT machinery|down regulation of viral budding through the ESCRT machinery|downregulation of viral budding via host ESCRT complex|downregulation of viral budding through the ESCRT machinery|down regulation of viral budding via host ESCRT complex|inhibition of viral budding via host ESCRT complex|negative regulation of viral budding through the ESCRT machinery|down-regulation of viral budding through the ESCRT machinery Any process that stops, prevents or reduces the frequency, rate or extent of viral budding via host ESCRT complex. GO:0048378 regulation of lateral mesodermal cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048378 regulation of lateral plate mesodermal cell fate specification Any process that modulates the frequency, rate or extent of lateral mesoderm cell fate specification. GO:0000392 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000392 GO:1903772 regulation of viral budding via host ESCRT complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903772 regulation of host-assisted viral budding|regulation of viral budding through the ESCRT machinery Any process that modulates the frequency, rate or extent of viral budding via host ESCRT complex. GO:0048377 lateral mesodermal cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048377 lateral plate mesodermal cell fate specification|lateral plate mesoderm cell fate specification|lateral mesoderm cell fate specification The process in which a cell becomes capable of differentiating autonomously into a lateral mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. GO:0000391 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000391 GO:1903782 regulation of sodium ion import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903782 Any process that modulates the frequency, rate or extent of sodium ion import across the plasma membrane. GO:1903781 positive regulation of cardiac conduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903781 upregulation of cardiac conduction|up-regulation of cardiac conduction|activation of cardiac conduction|up regulation of cardiac conduction Any process that activates or increases the frequency, rate or extent of cardiac conduction. GO:1903780 negative regulation of cardiac conduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903780 down regulation of cardiac conduction|inhibition of cardiac conduction|down-regulation of cardiac conduction|downregulation of cardiac conduction Any process that stops, prevents or reduces the frequency, rate or extent of cardiac conduction. GO:0048387 negative regulation of retinoic acid receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048387 negative regulation of RAR signaling pathway|negative regulation of retinoic acid receptor signalling pathway|down-regulation of retinoic acid receptor signaling pathway|negative regulation of RAR signalling pathway|downregulation of retinoic acid receptor signaling pathway|down regulation of retinoic acid receptor signaling pathway|inhibition of retinoic acid receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of retinoic acid receptor signaling pathway activity. GO:0000365 mRNA trans splicing, via spliceosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000365 nuclear mRNA trans splicing, via spliceosome|nuclear mRNA trans splicing, via U2-type spliceosome The joining together of exons from two different primary transcripts of messenger RNA (mRNA) via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced. GO:0097310 cap2 mRNA methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097310 cap2 mRNA capping Methylation of the ribose of the first and second nucleotides of a 5'-capped mRNA. GO:0048386 positive regulation of retinoic acid receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048386 stimulation of retinoic acid receptor signaling pathway|positive regulation of RAR signaling pathway|positive regulation of retinoic acid receptor signalling pathway|up-regulation of retinoic acid receptor signaling pathway|activation of retinoic acid receptor signaling pathway|up regulation of retinoic acid receptor signaling pathway|upregulation of retinoic acid receptor signaling pathway Any process that activates or increases the frequency, rate or extent of retinoic acid receptor signaling pathway activity. GO:0000364 obsolete second U2-type spliceosomal transesterification activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000364 second U2-type spliceosomal transesterification activity|3'-splice site cleavage, exon ligation OBSOLETE. Catalysis of the second transesterification reaction of U2-type spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure. The catalytic site is thought to be formed by U6 and/or U2 snRNAs and/or associated proteins. GO:0097312 obsolete bacterial biofilm matrix component biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0097312 biofilm matrix part OBSOLETE. Any constituent part of the biofilm matrix, a structure lying external to bacterial cells. A biofilm is an aggregate of surface-associated bacteria, and the biofilm matrix is the envelope of polymeric substances that surrounds the bacteria. GO:0000363 obsolete first U12-type spliceosomal transesterification activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000363 first U12-type spliceosomal transesterification activity|lariat formation, 5'-splice site cleavage OBSOLETE. Catalysis of the first transesterification reaction of U12-type spliceosomal mRNA splicing. The intron branch site adenosine is the nucleophile attacking the 5' splice site, resulting in cleavage at this position. In cis splicing, this is the step that forms a lariat structure of the intron RNA, which is still joined to the 3' exon. The catalytic site is thought to be formed by U6atac snRNA and/or U2atac snRNA, and/or associated proteins. GO:0048385 regulation of retinoic acid receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048385 regulation of RAR signaling pathway|regulation of retinoic acid receptor signalling pathway Any process that modulates the frequency, rate or extent of retinoic acid receptor signaling pathway activity. GO:0097311 bacterial biofilm matrix biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097311 A structure lying external to bacterial cells. A biofilm is an aggregate of surface-associated bacteria, and the biofilm matrix is the envelope of polymeric substances that surrounds the bacteria. GO:0048384 retinoic acid receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048384 RAR signaling pathway|retinoic acid receptor signalling pathway The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands. GO:0000362 obsolete first U2-type spliceosomal transesterification activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000362 lariat formation, 5'-splice site cleavage|first U2-type spliceosomal transesterification activity OBSOLETE. Catalysis of the first transesterification reaction of U2-type spliceosomal mRNA splicing. The intron branch site adenosine is the nucleophile attacking the 5' splice site, resulting in cleavage at this position. In cis splicing, this is the step that forms a lariat structure of the intron RNA, which is still joined to the 3' exon. The catalytic site is thought to be formed by U6 and/or U2 snRNA, and/or associated proteins. GO:0048383 mesectoderm development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048383 The process whose specific outcome is the progression of the mesectoderm over time, from its formation to the mature structure. In animal embryos, mesectoderm development processes give rise to both mesoderm and ectoderm tissues. GO:0000369 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000369 GO:0048382 mesendoderm development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048382 The process whose specific outcome is the progression of the mesendoderm over time, from its formation to the mature structure. In animal embryos, mesendoderm development gives rise to both mesoderm and endoderm tissues. GO:0000368 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000368 GO:0000367 obsolete second U12-type spliceosomal transesterification activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000367 second U12-type spliceosomal transesterification activity|3'-splice site cleavage, exon ligation OBSOLETE. Catalysis of the second transesterification reaction of U12-type spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure. The catalytic site is thought to be formed by U6 and/or U2 snRNAs and/or associated proteins. GO:0048381 lateral mesoderm structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048381 lateral plate mesoderm structural organization|lateral mesoderm structural organisation The process that contributes to the act of creating the structural organization of the lateral mesoderm. This process pertains to the physical shaping of a rudimentary structure. GO:0048380 negative regulation of lateral mesodermal cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048380 downregulation of lateral mesodermal cell fate specification|down regulation of lateral mesodermal cell fate specification|inhibition of lateral mesodermal cell fate specification|negative regulation of lateral plate mesodermal cell fate specification|down-regulation of lateral mesodermal cell fate specification Any process that stops, prevents, or reduces the frequency, rate or extent of lateral mesoderm cell fate specification. GO:0000366 intergenic mRNA trans splicing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000366 intergenic nuclear mRNA trans splicing The joining together of two independently transcribed RNAs from two different genes, each of which also produces mRNA(s) via cis-splicing. GO:1903789 regulation of amino acid transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903789 regulation of amino acid membrane transport Any process that modulates the frequency, rate or extent of amino acid transmembrane transport. GO:1903788 positive regulation of glutathione biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903788 up-regulation of glutathione synthesis|up-regulation of glutathione formation|upregulation of glutathione anabolism|positive regulation of glutathione biosynthesis|up regulation of glutathione biosynthesis|up regulation of glutathione biosynthetic process|upregulation of glutathione synthesis|upregulation of glutathione formation|up regulation of glutathione anabolism|upregulation of glutathione biosynthetic process|activation of glutathione anabolism|upregulation of glutathione biosynthesis|positive regulation of glutathione anabolism|up regulation of glutathione synthesis|activation of glutathione synthesis|positive regulation of glutathione synthesis|up regulation of glutathione formation|activation of glutathione formation|positive regulation of glutathione formation|up-regulation of glutathione biosynthesis|up-regulation of glutathione biosynthetic process|activation of glutathione biosynthesis|activation of glutathione biosynthetic process|up-regulation of glutathione anabolism Any process that activates or increases the frequency, rate or extent of glutathione biosynthetic process. GO:1903787 negative regulation of glutathione biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903787 inhibition of glutathione synthesis|negative regulation of glutathione biosynthesis|down-regulation of glutathione biosynthetic process|down-regulation of glutathione biosynthesis|inhibition of glutathione formation|down regulation of glutathione anabolism|downregulation of glutathione biosynthesis|downregulation of glutathione biosynthetic process|down regulation of glutathione synthesis|downregulation of glutathione anabolism|down regulation of glutathione biosynthetic process|down regulation of glutathione biosynthesis|inhibition of glutathione biosynthesis|down regulation of glutathione formation|inhibition of glutathione biosynthetic process|downregulation of glutathione synthesis|downregulation of glutathione formation|down-regulation of glutathione anabolism|negative regulation of glutathione anabolism|down-regulation of glutathione synthesis|negative regulation of glutathione synthesis|inhibition of glutathione anabolism|down-regulation of glutathione formation|negative regulation of glutathione formation Any process that stops, prevents or reduces the frequency, rate or extent of glutathione biosynthetic process. GO:1903786 regulation of glutathione biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903786 regulation of glutathione anabolism|regulation of glutathione biosynthesis|regulation of glutathione synthesis|regulation of glutathione formation Any process that modulates the frequency, rate or extent of glutathione biosynthetic process. GO:0000361 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000361 GO:1903785 L-valine transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903785 The directed movement of L-valine across a membrane. GO:0000360 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000360 GO:0048389 intermediate mesoderm development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048389 The process whose specific outcome is the progression of the intermediate mesoderm over time, from its formation to the mature structure. The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads. GO:1903784 positive regulation of sodium ion import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903784 upregulation of sodium ion import across plasma membrane|up-regulation of sodium ion import across plasma membrane|activation of sodium ion import across plasma membrane|up regulation of sodium ion import across plasma membrane Any process that activates or increases the frequency, rate or extent of sodium ion import across the plasma membrane. GO:1903783 negative regulation of sodium ion import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903783 down regulation of sodium ion import across plasma membrane|inhibition of sodium ion import across plasma membrane|down-regulation of sodium ion import across plasma membrane|downregulation of sodium ion import across plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion import across the plasma membrane. GO:0048388 endosomal lumen acidification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048388 Any process that reduces the pH of the endosomal lumen, measured by the concentration of the hydrogen ion. GO:1903793 positive regulation of anion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903793 activation of anion transport|up-regulation of anion transport|upregulation of anion transport|up regulation of anion transport Any process that activates or increases the frequency, rate or extent of anion transport. GO:1903792 negative regulation of anion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903792 down-regulation of anion transport|inhibition of anion transport|down regulation of anion transport|downregulation of anion transport Any process that stops, prevents or reduces the frequency, rate or extent of anion transport. GO:1903791 uracil transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903791 The process in which uracil is transported across a membrane. GO:1903790 guanine nucleotide transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903790 guanyl nucleotide transmembrane transport The process in which a guanyl nucleotide is transported across a membrane. GO:0048390 intermediate mesoderm morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048390 The process in which the anatomical structures of the intermediate mesoderm are generated and organized. GO:0097318 invasive growth in response to abiotic stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097318 The growth of colonies in filamentous chains of cells as a result of a abiotic stimulus. An example of this process is found in Candida albicans. GO:0097317 invasive growth in response to biotic stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097317 The growth of colonies in filamentous chains of cells as a result of a biotic stimulus. An example of this is Candida albicans forming invasive filaments in agar medium in response to a serum stimulus. GO:0097319 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0097319 GO:0097314 apoptosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097314 apoptosome formation The aggregation, arrangement and bonding together of the apoptosome, a multisubunit protein complex involved in the signaling phase of the apoptotic process. GO:0097313 bacterial biofilm matrix surface biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097313 The external part of the biofilm matrix, a structure lying external to bacterial cells. A biofilm is an aggregate of surface-associated bacteria, and the biofilm matrix is the envelope of polymeric substances that surrounds the bacteria. GO:0097316 cellular response to N-acetyl-D-glucosamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097316 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an N-acetyl-D-glucosamine stimulus. GO:0097315 response to N-acetyl-D-glucosamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097315 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an N-acetyl-D-glucosamine stimulus. GO:0097321 cell growth mode switching, filamentous to budding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097321 The process in which a cell switches from growing as a filament (elongated cells attached end-to-end) to growing as a round budding cell. An example of this is observed in Candida albicans. GO:0000376 RNA splicing, via transesterification reactions with guanosine as nucleophile biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000376 Splicing of RNA via a series of two transesterification reactions with exogenous guanosine as the initiating nucleophile. GO:0048398 intermediate mesodermal cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048398 intermediate mesoderm cell fate specification The process in which a cell becomes capable of differentiating autonomously into an intermediate mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. GO:0000375 RNA splicing, via transesterification reactions biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0000375 spliceosomal catalysis|RNA splicing factor activity, transesterification mechanism|pre-mRNA splicing factor activity Splicing of RNA via a series of two transesterification reactions. GO:0097320 plasma membrane tubulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097320 vesicle scission|membrane tubulation A membrane tubulation process occurring in a plasma membrane. GO:0048397 positive regulation of intermediate mesodermal cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048397 up regulation of intermediate mesodermal cell fate determination|activation of intermediate mesodermal cell fate determination|stimulation of intermediate mesodermal cell fate determination|up-regulation of intermediate mesodermal cell fate determination|upregulation of intermediate mesodermal cell fate determination Any process that activates or increases the frequency, rate or extent of intermediate mesoderm cell fate determination. GO:0048396 negative regulation of intermediate mesodermal cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048396 downregulation of intermediate mesodermal cell fate determination|down-regulation of intermediate mesodermal cell fate determination|inhibition of intermediate mesodermal cell fate determination|down regulation of intermediate mesodermal cell fate determination Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate mesoderm cell fate determination. GO:0097323 B cell adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097323 The attachment of a B cell to another cell via adhesion molecules. GO:0000374 Group III intron splicing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000374 mRNA splicing The splicing of Group III introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group III introns, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions begun by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat. Though very similar in structure and mechanism to Group II introns, Group III introns are smaller and more streamlined and the splice site consensus sequences are not as well conserved. GO:0048395 regulation of intermediate mesodermal cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048395 Any process that modulates the frequency, rate or extent of intermediate mesoderm cell fate determination. GO:0097322 7SK snRNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097322 7SK small nuclear RNA binding Interacting selectively and non-covalently with a 7SK small nuclear RNA (7SK snRNA). GO:0000373 Group II intron splicing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000373 mRNA splicing The splicing of Group II introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group II introns and containing splice site consensus sequences, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions (mechanistically similar to those for splicing of nuclear mRNAs) initiated by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat. GO:0048394 intermediate mesodermal cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048394 intermediate mesoderm cell fate determination The process in which a cell becomes capable of differentiating autonomously into a intermediate mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed. GO:0048393 intermediate mesodermal cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048393 intermediate mesoderm cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into an intermediate mesoderm cell. GO:0000379 tRNA-type intron splice site recognition and cleavage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000379 RNA processing that begins when the tertiary structure of a tRNA type intron is recognized, and ends when the endonucleolytic cleavage of the RNA at both the 5' and 3' splice sites occurs. GO:0048392 intermediate mesodermal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048392 intermediate mesoderm cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an intermediate mesoderm cell. GO:0000378 RNA exon ligation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000378 The RNA metabolic process that joins two exons, each of which has free ends that were generated by endonucleolytic cleavages, by a ligation reaction. GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000377 lariat RNA biosynthesis|lariat RNA formation Splicing of RNA via a series of two transesterification reactions with a bulged adenosine residue from the intron branch point as the initiating nucleophile. When the initial RNA for the splicing reaction is a single molecule (cis splicing), the excised intron is released in a lariat structure. GO:0048391 intermediate mesoderm formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048391 The process that gives rise to the intermediate mesoderm. This process pertains to the initial formation of the structure from unspecified parts. GO:1903799 negative regulation of production of miRNAs involved in gene silencing by miRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903799 downregulation of microRNA metabolism|negative regulation of production of microRNAs involved in gene silencing by microRNA|down-regulation of production of microRNAs involved in gene silencing by microRNA|downregulation of production of miRNAs involved in gene silencing by miRNA|downregulation of miRNA-mediated gene silencing, production of miRNAs|inhibition of gene silencing by miRNA, production of miRNAs|down regulation of microRNA biogenesis|inhibition of microRNA metabolic process|negative regulation of microRNA biosynthesis|down-regulation of miRNA processing|down-regulation of microRNA biosynthesis|negative regulation of microRNA biosynthetic process|down regulation of production of miRNAs involved in gene silencing by miRNA|down-regulation of microRNA biosynthetic process|negative regulation of miRNA processing|inhibition of production of miRNAs involved in gene silencing by miRNA|downregulation of miRNA biogenesis|negative regulation of microRNA-mediated gene silencing, production of microRNAs|down-regulation of microRNA-mediated gene silencing, production of microRNAs|negative regulation of microRNA metabolism|downregulation of microRNA biogenesis|down-regulation of microRNA metabolism|downregulation of production of microRNAs involved in gene silencing by microRNA|down regulation of miRNA biogenesis|negative regulation of miRNA-mediated gene silencing, production of miRNAs|down-regulation of miRNA-mediated gene silencing, production of miRNAs|inhibition of microRNA-mediated gene silencing, production of microRNAs|down regulation of production of microRNAs involved in gene silencing by microRNA|inhibition of production of microRNAs involved in gene silencing by microRNA|downregulation of miRNA processing|negative regulation of microRNA metabolic process|down-regulation of microRNA metabolic process|inhibition of miRNA-mediated gene silencing, production of miRNAs|inhibition of miRNA biogenesis|down-regulation of microRNA biogenesis|inhibition of microRNA biosynthetic process|inhibition of microRNA biosynthesis|down regulation of gene silencing by miRNA, production of miRNAs|negative regulation of microRNA biogenesis|down regulation of miRNA processing|inhibition of miRNA processing|inhibition of microRNA metabolism|downregulation of gene silencing by miRNA, production of miRNAs|down regulation of microRNA biosynthetic process|down-regulation of production of miRNAs involved in gene silencing by miRNA|down regulation of microRNA biosynthesis|downregulation of microRNA metabolic process|down regulation of microRNA-mediated gene silencing, production of microRNAs|down regulation of microRNA metabolism|downregulation of microRNA biosynthetic process|downregulation of microRNA biosynthesis|negative regulation of miRNA biogenesis|down regulation of microRNA metabolic process|inhibition of microRNA biogenesis|down-regulation of miRNA biogenesis|negative regulation of gene silencing by miRNA, production of miRNAs|downregulation of microRNA-mediated gene silencing, production of microRNAs|down-regulation of gene silencing by miRNA, production of miRNAs|down regulation of miRNA-mediated gene silencing, production of miRNAs Any process that stops, prevents or reduces the frequency, rate or extent of production of miRNAs involved in gene silencing by miRNA. GO:1903798 regulation of production of miRNAs involved in gene silencing by miRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903798 regulation of miRNA-mediated gene silencing, production of miRNAs|regulation of microRNA biogenesis|regulation of miRNA biogenesis|regulation of production of microRNAs involved in gene silencing by microRNA|regulation of miRNA processing|regulation of gene silencing by miRNA, production of miRNAs|regulation of microRNA processing|regulation of microRNA biosynthesis|regulation of microRNA biosynthetic process|regulation of microRNA metabolic process|regulation of microRNA-mediated gene silencing, production of microRNAs|regulation of microRNA metabolism Any process that modulates the frequency, rate or extent of production of miRNAs involved in gene silencing by miRNA. GO:1903797 positive regulation of inorganic anion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903797 up regulation of inorganic anion transmembrane transport|up regulation of transmembrane inorganic anion transport|activation of inorganic anion transmembrane transport|activation of transmembrane inorganic anion transport|positive regulation of transmembrane inorganic anion transport|upregulation of inorganic anion membrane transport|up-regulation of inorganic anion membrane transport|activation of inorganic anion membrane transport|up-regulation of inorganic anion transmembrane transport|up-regulation of transmembrane inorganic anion transport|upregulation of inorganic anion transmembrane transport|upregulation of transmembrane inorganic anion transport|positive regulation of inorganic anion membrane transport|up regulation of inorganic anion membrane transport Any process that activates or increases the frequency, rate or extent of inorganic anion transmembrane transport. GO:0000372 Group I intron splicing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000372 mRNA splicing The splicing of Group I introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group I introns and involved in determining the locations of the splice sites (there do not appear to be consensus splice site sequences) as well as having a role in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions, generally with exogenous guanosine as the initiating nucleophile. The intron is excised as a linear piece (though it may subsequently circularize). GO:1903796 negative regulation of inorganic anion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903796 down regulation of inorganic anion membrane transport|inhibition of inorganic anion membrane transport|negative regulation of transmembrane inorganic anion transport|down-regulation of transmembrane inorganic anion transport|down-regulation of inorganic anion transmembrane transport|inhibition of transmembrane inorganic anion transport|inhibition of inorganic anion transmembrane transport|down-regulation of inorganic anion membrane transport|negative regulation of inorganic anion membrane transport|down regulation of transmembrane inorganic anion transport|down regulation of inorganic anion transmembrane transport|downregulation of inorganic anion membrane transport|downregulation of inorganic anion transmembrane transport|downregulation of transmembrane inorganic anion transport Any process that stops, prevents or reduces the frequency, rate or extent of inorganic anion transmembrane transport. GO:0000371 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000371 GO:0000370 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000370 GO:1903795 regulation of inorganic anion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903795 regulation of transmembrane inorganic anion transport|regulation of inorganic anion membrane transport Any process that modulates the frequency, rate or extent of inorganic anion transmembrane transport. GO:0048399 regulation of intermediate mesodermal cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048399 Any process that modulates the frequency, rate or extent of intermediate mesoderm cell fate specification. GO:1903794 cortisol binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1903794 Interacting selectively and non-covalently with cortisol. GO:0097329 response to antimetabolite biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097329 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimetabolite stimulus. An antimetabolite is a substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization. GO:0097328 response to carboplatin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097328 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carboplatin stimulus. GO:0097325 melanocyte proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097325 The multiplication or reproduction of melanocytes, resulting in the expansion of a cell population. A melanocyte is a pigment cell derived from the neural crest. It contains melanin-filled pigment granules, which give a brown to black appearance. GO:0097324 melanocyte migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097324 The orderly movement of melanocytes from one site to another, often during the development of a multicellular organism. A melanocyte is a pigment cell derived from the neural crest. It contains melanin-filled pigment granules, which give a brown to black appearance. GO:0097327 response to antineoplastic agent biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097327 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antineoplastic agent stimulus. An antineoplastic agent is a substance that inhibits or prevents the proliferation of neoplasms. GO:0097326 melanocyte adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097326 The attachment of a melanocyte to another cell via adhesion molecules. GO:0000343 plastid-encoded plastid RNA polymerase complex A biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000343 PEP-A A plastid-encoded DNA-directed RNA polymerase complex that resembles eubacterial multisubunit RNA polymerases, with a core composed of alpha, beta, and beta-prime subunits. An additional subunit, a sigma factor, is required for promoter recognition. PEP-A is generated from the PEP-B form during chloroplast maturation to generate a complex composed of at least thirteen polypeptides that is not sensitive to the antibiotic rifampicin, like its precursor form the PEP-B complex. GO:0000342 RNA cap 4 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000342 Interacting selectively and non-covalently with a hypermethylated cap structure consisting of 7-methylguanosine (m(7)G) followed by four methylated nucleotides (cap 4): 7-methylguanosine-ppp-N6, N6, 2'-O-trimethyladenosine-p-2'-O-methyladenosine-p-2'-O-methylcytosine-p-N3, 2'-O-dimethyluridine Such caps are known to be found at the 5' ends of SL RNAs of trypanosomatid protozoa. GO:0000341 RNA trimethylguanosine cap binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000341 RNA m2,2,7G cap binding Interacting selectively and non-covalently with the trimethylguanosine (m(3)(2,2,7)-GTP) group located at the 5' end of some RNA molecules. Such trimethylated cap structures, generally produced by posttranscriptional modification of a 7-methylguanosine cap, are often found on snRNAs and snoRNAs transcribed by RNA polymerase II, but have also be found on snRNAs transcribed by RNA polymerase III. They have also been found on a subset of the mRNA population in some species, e.g. C. elegans. GO:0000340 RNA 7-methylguanosine cap binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000340 RNA m7G cap binding Interacting selectively and non-covalently with the 7-methylguanosine group added cotranscriptionally to the 5' end of RNA molecules transcribed by polymerase II. GO:0000347 THO complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0000347 The THO complex is a nuclear complex that is required for transcription elongation through genes containing tandemly repeated DNA sequences. The THO complex is also part of the TREX (TRanscription EXport) complex that is involved in coupling transcription to export of mRNAs to the cytoplasm. In S. cerevisiae, it is composed of four subunits: Hpr1p, Tho2p, Thp1p, and Mft1p, while the human complex is composed of 7 subunits. GO:0000346 transcription export complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0000346 TREX complex The transcription export (TREX) complex couples transcription elongation by RNA polymerase II to mRNA export. The complex associates with the polymerase and travels with it along the length of the transcribed gene. TREX is composed of the THO transcription elongation complex as well as other proteins that couple THO to mRNA export proteins. The TREX complex is known to be found in a wide range of eukaryotes, including S. cerevisiae and metazoans. GO:0000345 cytosolic DNA-directed RNA polymerase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000345 The eubacterial DNA-directed RNA polymerase is a multisubunit complex with a core composed of the essential subunits beta-prime, beta, and two copies of alpha and a fifth nonessential subunit called omega. An additional subunit, a sigma factor, is required for promoter recognition and specificity. GO:0000344 plastid-encoded plastid RNA polymerase complex B biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000344 PEP-B A plastid-encoded DNA-directed RNA polymerase complex that resembles eubacterial multisubunit RNA polymerases with a core composed of alpha, beta, and beta-prime subunits. An additional subunit, a sigma factor, is required for promoter recognition. PEP-B is distinguished from PEP-A by its sensitivity to the antibiotic rifampicin. PEP-B is found in both etioplasts and chloroplasts, but is the predominate form in etioplasts. It forms the core of the PEP-A form; the conversion from PEP-B to PEP-A occurs during chloroplast maturation. GO:0000349 generation of catalytic spliceosome for first transesterification step biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000349 formation of catalytic spliceosome for first transesterification step|spliceosomal C1 complex biosynthesis|spliceosomal A2-2 complex biosynthesis|spliceosomal A2-2 complex formation|catalytic spliceosome assembly for first transesterification step|U2-type catalytic spliceosome formation for first transesterification step|spliceosomal C1 complex formation|U12-type catalytic spliceosome formation for first transesterification step Formation of a catalytic spliceosome complex ready to perform the first splicing reaction. This occurs by an ATP-dependent conformational change of the pre-catalytic spliceosome. GO:0000348 mRNA branch site recognition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000348 nuclear mRNA branch site recognition|spliceosomal A complex biosynthesis|spliceosomal B complex biosynthesis|spliceosomal B complex formation|spliceosomal A complex formation|U2-type nuclear mRNA branch site recognition|U12-type nuclear mRNA branch site recognition Recognition of the pre-mRNA branch site sequence by components of the assembling spliceosome. GO:0000354 cis assembly of pre-catalytic spliceosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000354 spliceosomal B1 complex formation|cis assembly of U12-type pre-catalytic spliceosome|formation of spliceosomal A2-1 complex|formation of spliceosomal B1 complex|cis assembly of U2-type pre-catalytic spliceosome|spliceosomal B1 complex biosynthesis|spliceosomal A2-1 complex biosynthesis|spliceosomal A2-1 complex formation Assembly of a spliceosomal complex containing the intact pre-mRNA and all of the spliceosomal snRNPs. This occurs when the tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner. GO:0000353 formation of quadruple SL/U4/U5/U6 snRNP biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000353 Formation of a quadruple snRNP complex composed of the spliced leader (SL) RNA along with the U4/U6-U5 tri-snRNP complex. Interactions that may facilitate this include a duplex between the SL and U6 RNAs and interactions between the U5 RNA and the exon sequence at the 5' splice site within the SL RNA. GO:0097301 regulation of potassium ion concentration by positive regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097301 potassium ion homeostasis by positive regulation of transcription from RNA polymerase II promoter|cellular potassium ion homeostasis by positive regulation of transcription from RNA polymerase II promoter Any process that regulates the internal concentration of potassium ions at the level of a cell by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:0000352 trans assembly of SL-containing precatalytic spliceosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000352 trans assembly of spliced leader-containing precatalytic spliceosome Assembly of a spliceosomal complex containing the SL RNA and the pre-mRNA to be joined, as well as all the spliceosomal snRNPs involved in trans leader splicing. Formation of the trans leader spliceosome brings together the quadruple SL/U4/U5/U6 snRNP and the complex of the U2 snRNP with the splice site of the pre-mRNA. GO:0097300 programmed necrotic cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097300 programmed cell death by necrosis|regulated necrosis A necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors. GO:0000351 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000351 GO:0000358 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000358 GO:0000357 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000357 GO:0000356 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000356 GO:0000355 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000355 GO:0000350 generation of catalytic spliceosome for second transesterification step biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000350 formation of spliceosomal A2-2 complex|formation of catalytic U2-type spliceosome for second transesterification step|formation of spliceosomal C1 complex|spliceosomal C2 complex biosynthesis|lariat formation, 5'-splice site cleavage|spliceosomal A2-3 complex formation|spliceosomal A2-3 complex biosynthesis|catalytic spliceosome assembly for second transesterification step|formation of catalytic spliceosome for second transesterification step|formation of catalytic U12-type spliceosome for second transesterification step|spliceosomal C2 complex formation Conformational rearrangement of the spliceosomal complex containing the RNA products from the 1st step of splicing to form the catalytic site for the second step of splicing. GO:0097307 response to farnesol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097307 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a farnesol stimulus. GO:0097306 cellular response to alcohol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097306 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus. GO:0097309 cap1 mRNA methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097309 cap1 mRNA capping Methylation of the ribose of the first nucleotide of a 5'-capped mRNA. GO:0000359 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000359 GO:0097308 cellular response to farnesol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097308 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a farnesol stimulus. GO:0097303 lipoprotein biosynthetic process via N-acyl transfer biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097303 lipoprotein biosynthesis (N-acyl transfer) The chemical reactions and pathways by which N-acyl transfer leads to formation of a water-soluble protein-lipid complex. GO:0097302 lipoprotein biosynthetic process via diacylglyceryl transfer biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097302 lipoprotein biosynthesis (diacylglyceryl transfer) The chemical reactions and pathways by which diacylglyceryl transfer leads to formation of a water-soluble protein-lipid complex. GO:0097305 response to alcohol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097305 process resulting in tolerance to alcohol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus. GO:0097304 lipoprotein biosynthetic process via signal peptide cleavage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097304 lipoprotein biosynthesis (signal peptide cleavage) The chemical reactions and pathways by which signal peptide cleavage leads to formation of a water-soluble protein-lipid complex. CHEBI:73258 gibberellin A34(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73258 CHEBI:73257 gibberellin A20 methyl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73257 CHEBI:73259 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73259 UBERON:0035165 posterior surface of prostate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035165 posterior surface of prostate gland|facies posterior (prostatae)|facies posterior prostatae The flattened aspect of the prostate with a slight furrow facing the rectum and anus. UBERON:0011198 muscle layer of large intestine biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011198 tunica muscularis intestini crassi|muscularis externa of large intestine|muscular layer of large intestine|muscular coat of large intestine A muscle layer that is part of a large intestine. UBERON:0011197 parathyroid epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011197 An epithelium that is part of a parathyroid gland. CL:0001055 CD14-positive, CD16-low monocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001055 intermediate monocyte, human An intermediate monocyte that is CD14-positive and with low amounts of CD16. CL:0001054 CD14-positive monocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001054 monocyte A monocyte that expresses CD14 and is negative for the lineage markers CD3, CD19, and CD20. CHEBI:38920 benzochromene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38920 PR:000001661 proteinase-activated receptor 1 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001661 coagulation factor II receptor|CF2R|TR|thrombin receptor|PAR1|F2R|PAR-1 A proteinase-activated receptor that is a translation product of the human F2R gene or a 1:1 ortholog thereof. It is activated by thrombin, which cleaves the mature peptide, exposing a new amino end. The new N-terminal residues act as a tethered ligand that induces activity. PR:000001660 prostaglandin F2-alpha receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001660 prostanoid FP receptor|PTGFR|PGF receptor|PGF2-alpha receptor A prostanoid receptor that is a translation product of the human PTGFR gene or a 1:1 ortholog thereof. The preferred ligand is prostaglandin F2a. This receptor is particularly prevalent in the corpus luteum, but is expressed in other tissues also. CL:0001059 common myeloid progenitor, CD34-positive biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001059 common myeloid precursor, CD34-positive|CFU-GEMM|CFU-S|pluripotent stem cell (bone marrow)|multipotential myeloid stem cell|myeloid stem cell|CMP|colony forming unit granulocyte, erythrocyte, macrophage, and megakaryocyte A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages. These cells are CD34-positive, and express Gata1, Gata2, C/EBPa, and Pu.1. CHEBI:38925 benzopteridine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38925 CHEBI:38922 dibenzofurans biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38922 CHEBI:73250 gibberellin A1 methyl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73250 CHEBI:73252 gibberellin A4 methyl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73252 CHEBI:73251 gibberellin A4(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73251 CL:0001051 CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001051 CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T lymphocyte|CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T-cell|non-Th1/Th17 CD4+ T cell|CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T-lymphocyte A CD4-positive, alpha-beta T cell that has the phenotype CXCR3-negative, CCR6-negative. CHEBI:73254 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73254 CL:0001050 effector CD8-positive, alpha-beta T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001050 effector CD8-positive, alpha-beta T-cell|effector CD8-positive, alpha-beta T-lymphocyte|effector CD8+ T cell|effector CD8-positive, alpha-beta T lymphocyte A CD8-positive, alpha-beta T cell with the phenotype CCR7-negative, CD45RA-positive. CHEBI:73253 gibberellin A3 methyl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73253 CL:0001053 IgD-negative memory B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001053 IgD- memory B cell A memory B cell that lacks expression of surface IgD. CHEBI:73256 gibberellin A9 methyl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73256 CL:0001052 CD8-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001052 non-Tc1/Tc17 CD8+ T cell|CD8-positive, CXCR3-negative, CCR6-negative, alpha-beta T-lymphocyte|CD8-positive, CXCR3-negative, CCR6-negative, alpha-beta T lymphocyte|CD8-positive, CXCR3-negative, CCR6-negative, alpha-beta T-cell A CD8-positive, alpha-beta T cell that has the phenotype CXCR3-negative, CCR6-negative. CHEBI:73255 gibberellin A9(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73255 CHEBI:73268 gibberellin ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73268 UBERON:0035174 right ear biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035174 The organ of hearing located on the right side of the head. UBERON:0011185 gastrointestinal sphincter biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011185 A sphincter muscle that is part of the gastrointestinal system CHEBI:14949 N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_14949 UBERON:0011189 lamina propria of large intestine biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011189 large intestine lamina propria|lamina propria of mucosa of large intestine|large intestinal lamina propria A lamina propria that is part of a large intestine. CL:0001066 erythroid progenitor cell, mammalian biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001066 blast forming unit erythroid|colony forming unit erythroid|burst forming unit erythroid|erythroid stem cell|CFU-E|BFU-E A progenitor cell committed to the erythroid lineage. This cell is ter119-positive but lacks expression of other hematopoietic lineage markers (lin-negative). CHEBI:38932 pyridopyrimidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38932 CL:0001065 innate lymphoid cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001065 A lymphocyte that lacks characteristic T cell, B cell, myeloid cell, and dendritic cell markers, that functions as part of the innate immune response to produce cytokines and other effector responses. CL:0001068 ILC1 biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001068 A group 1 innate lymphoid cell that is non-cytotoxic. CL:0001067 group 1 innate lymphoid cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001067 An innate lymphoid cell that is capable of producing the type 1 cytokine IFN-gamma, but not Th2 or Th17 cell-associated cytokines. CL:0001069 group 2 innate lymphoid cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001069 natural helper cell|ILC2|nuocyte An innate lymphoid cell that is capable of producing T-helper 2-cell associated cytokines upon stimulation. PR:000001676 thromboxane A2 receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001676 prostanoid TP receptor|TXA2-R|TBXA2R A prostanoid receptor that is a translation product of the human TBXA2R gene or a 1:1 ortholog thereof. The preferred ligand is thromboxane A2. This receptor is found mainly in vascular smooth muscle, where it mediates vasoconstriction, in platelets, where it mediates aggregation, and in airway smooth muscle. CHEBI:38934 purvalanol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38934 CHEBI:38933 3-aminopropane-1-thiol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38933 CHEBI:73260 gibberellin A34 methyl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73260 CL:0001060 hematopoietic oligopotent progenitor cell, lineage-negative biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001060 A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities. Cell lacks hematopoeitic lineage markers. CHEBI:73263 cyclooxygenase 3 inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73263 CHEBI:73262 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73262 CHEBI:73265 archaeosine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73265 CHEBI:73264 1-hexadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73264 CHEBI:73267 oxidative phosphorylation inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73267 UBERON:0011171 joint connecting upper and lower jaws biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011171 jaw joint|craniomandibular joint Synovial joint that articulates bones of upper and lower jaw. CL:0001033 hippocampal granule cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001033 Granule cell that is part of the hippocampus. CL:0001032 cortical granule cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001032 Granule cell that is part of the cerebral cortex. CL:0001035 bone cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001035 A connective tissue cell found in bone. CHEBI:14973 pyrazole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_14973 CHEBI:73271 archaeosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73271 CL:0001031 cerebellar granule cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001031 Granule cell that is part of the cerebellum. SO:0000577 centromere biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000577 http://en.wikipedia.org/wiki/Centromere INSDC_feature:centromere A region of chromosome where the spindle fibers attach during mitosis and meiosis. CL:0001030 CD117-positive common myeloid progenitor OR CD217-positive common lymphoid progenitor biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001030 UBERON:0011160 nasal suture biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011160 A suture joining a nasal bone to another bone. UBERON:0035198 superficial lymphatic vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035198 superficial lymph vessel The tubules that carry lymph throughout the body that are just beneath the surface of the skin. UBERON:0011164 neurocranium bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011164 chondrocranium bone A bone that is part of a neurocranium [Automatically generated definition]. CL:0001044 effector CD4-positive, alpha-beta T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001044 effector CD4-positive, alpha-beta T-lymphocyte|effector CD4+ T cell|effector CD4-positive, alpha-beta T lymphocyte|effector CD4-positive, alpha-beta T-cell A CD4-positive, alpha-beta T cell with the phenotype CCR7-negative, CD45RA-positive. CHEBI:73281 (2S)-versicolorone(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73281 PR:000001656 prostaglandin D2 receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001656 PGD2 receptor|PTGDR|PGD receptor|prostanoid DP receptor A prostanoid receptor that is a translation product of the human PTGDR gene or a 1:1 ortholog thereof. The preferred ligand is prostaglandin D2 (PGD2). This receptor is found mainly in blood platelets, vascular smooth muscle, and nervous tissue. It is the least upiquitous of the prostanoid receptors, almost always occurring in association with other prostanoid receptor types. PR:000001655 prostacyclin receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001655 PTGIR|PGI receptor|prostanoid IP receptor|PRIPR|PGI2 receptor|prostaglandin I2 receptor A prostanoid receptor that is a translation product of the human PTGIR gene or a 1:1 ortholog thereof. The preferred ligand is prostacyclin (prostaglandin I2, PGI2). This receptor is widely distributed in blood platelets, vascular smooth muscle and nerve cells. PR:000001658 prostaglandin E2 receptor EP2 subtype biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001658 Ptgerep2|PGE receptor EP2 subtype|prostanoid EP2 receptor|PTGER2|prostaglandin E2 receptor EP2|PGE2 receptor EP2 subtype A prostanoid receptor that is a translation product of the human PTGER2 gene or a 1:1 ortholog thereof. The preferred ligand is prostaglandin E2 (PGE2). This receptor is expressed mediates various effects, including relaxation of vascular smooth muscles, nonacid secretion from epithelial cells, inhibition of mediator release from mast cells and basophils, and activation of sensory afferent nerves. PR:000001657 prostaglandin E2 receptor EP1 subtype biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001657 Ptgerep1|PGE receptor EP1 subtype|prostanoid EP1 receptor|PTGER1|prostaglandin E2 receptor EP1|PGE2 receptor EP1 subtype A prostanoid receptor that is a translation product of the human PTGER1 gene or a 1:1 ortholog thereof. The preferred ligand is prostaglandin E2 (PGE2). This receptor has limited expression, although it is more evident in rodents than in other mammals. PR:000001659 prostaglandin E2 receptor EP3 subtype biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001659 Ptgerep3|PGE receptor EP3 subtype|PGE2-R|prostanoid EP3 receptor|PTGER3|prostaglandin E2 receptor EP3|PGE2 receptor EP3 subtype A prostanoid receptor that is a translation product of the human PTGER3 gene or a 1:1 ortholog thereof. The preferred ligand is prostaglandin E2 (PGE2). This receptor is the most ubiquitous of the prostaglandin E2 receptors, mediating contraction of gastrointestinal, uterine, and vascular smooth muscle, inhibition of neurotransmitter release from autonomic nerves, inhibition of lipolysis in adipocytes, inhibition of acid secretion from gastric mucosa, and inhibition of water reabsorption in kidney. CL:0001042 T-helper 22 cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001042 Th22 T-lymphocyte|Th22 T cell|Th22 T lymphocyte|Th22 cell|T(H)-22 cell|Th22 T-cell|helper T cell type 22 CD4-positive, alpha-beta T cell that produces IL-22. CL:0001041 CD8-positive, CXCR3-positive, alpha-beta regulatory T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001041 CD8-positive, CXCR3-positive, alpha-beta regulatory T lymphocyte|CD8+CXCR3+ T cell|CD8+CXCR3+ T lymphocyte|CD8+CXCR3+ T(reg)|CD8-positive, CXCR3-positive, T(reg)|CD8-positive, CXCR3-positive, alpha-beta regulatory T-cell|CD8+CXCR3+ Treg|CD8-positive, CXCR3-positive, Treg|CD8-positive, CXCR3-positive, alpha-beta regulatory T-lymphocyte|CD8+CXCR3+ T-cell A CD8-positive alpha-beta-positive T cell with the phenotype CXCR3-positive and having suppressor function. They are capable of producing IL-10, suppressing proliferation, and suppressing IFN-gamma production. GO:1903709 uterine gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903709 set of uterine glands development|glandular part of endometrium development|uterine glands set development|uterine glands development|endometrium gland development|glandulae uterinae development|endometrial gland development The process whose specific outcome is the progression of an uterine gland over time, from its formation to the mature structure. GO:1903708 positive regulation of hemopoiesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903708 positive regulation of haemopoiesis|up regulation of haemopoiesis|up regulation of blood cell biosynthesis|up regulation of hemopoiesis|positive regulation of blood cell biosynthesis|activation of blood cell biosynthesis|activation of hemopoiesis|upregulation of hematopoiesis|upregulation of blood cell formation|upregulation of haemopoiesis|up-regulation of blood cell biosynthesis|up regulation of hematopoiesis|up-regulation of hemopoiesis|up-regulation of blood cell formation|activation of blood cell formation|activation of hematopoiesis|positive regulation of hematopoiesis|up-regulation of haemopoiesis|activation of haemopoiesis|upregulation of blood cell biosynthesis|upregulation of hemopoiesis|positive regulation of blood cell formation|up-regulation of hematopoiesis|up regulation of blood cell formation Any process that activates or increases the frequency, rate or extent of hemopoiesis. GO:1903707 negative regulation of hemopoiesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903707 downregulation of blood cell formation|downregulation of hemopoiesis|down regulation of blood cell formation|downregulation of haemopoiesis|inhibition of blood cell formation|down-regulation of blood cell biosynthesis|negative regulation of blood cell biosynthesis|down-regulation of hemopoiesis|down regulation of hematopoiesis|down regulation of haemopoiesis|inhibition of haemopoiesis|downregulation of hematopoiesis|inhibition of blood cell biosynthesis|inhibition of hemopoiesis|down-regulation of hematopoiesis|negative regulation of hematopoiesis|down-regulation of blood cell formation|negative regulation of blood cell formation|down regulation of blood cell biosynthesis|down-regulation of haemopoiesis|down regulation of hemopoiesis|negative regulation of haemopoiesis|inhibition of hematopoiesis|downregulation of blood cell biosynthesis Any process that stops, prevents or reduces the frequency, rate or extent of hemopoiesis. GO:1903706 regulation of hemopoiesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903706 regulation of blood cell formation|regulation of haemopoiesis|regulation of hematopoiesis|regulation of blood cell biosynthesis Any process that modulates the frequency, rate or extent of hemopoiesis. GO:1903705 positive regulation of production of siRNA involved in RNA interference biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903705 up-regulation of RNA interference, production of guide RNAs|up regulation of production of siRNA involved in RNA interference|activation of RNA interference, production of guide RNAs|up-regulation of production of guide RNAs involved in RNA interference|up regulation of RNA interference, production of siRNA|positive regulation of RNA interference, production of siRNA|activation of RNA interference, production of siRNA|upregulation of production of siRNA involved in RNA interference|positive regulation of RNA interference, production of guide RNAs|upregulation of production of guide RNAs involved in RNA interference|up regulation of RNA interference, production of guide RNAs|up-regulation of RNA interference, production of siRNA|up-regulation of production of siRNA involved in RNA interference|activation of production of siRNA involved in RNA interference|upregulation of RNA interference, production of guide RNAs|up regulation of production of guide RNAs involved in RNA interference|positive regulation of production of guide RNAs involved in RNA interference|activation of production of guide RNAs involved in RNA interference|upregulation of RNA interference, production of siRNA Any process that activates or increases the frequency, rate or extent of production of siRNA involved in RNA interference. GO:1903704 negative regulation of production of siRNA involved in RNA interference biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903704 negative regulation of production of guide RNAs involved in RNA interference|down-regulation of production of guide RNAs involved in RNA interference|down regulation of RNA interference, production of siRNA|downregulation of RNA interference, production of siRNA|inhibition of production of guide RNAs involved in RNA interference|downregulation of production of siRNA involved in RNA interference|down-regulation of RNA interference, production of guide RNAs|down regulation of production of siRNA involved in RNA interference|negative regulation of RNA interference, production of guide RNAs|inhibition of production of siRNA involved in RNA interference|negative regulation of RNA interference, production of siRNA|down-regulation of RNA interference, production of siRNA|downregulation of RNA interference, production of guide RNAs|down regulation of production of guide RNAs involved in RNA interference|inhibition of RNA interference, production of siRNA|down regulation of RNA interference, production of guide RNAs|downregulation of production of guide RNAs involved in RNA interference|inhibition of RNA interference, production of guide RNAs|down-regulation of production of siRNA involved in RNA interference Any process that stops, prevents or reduces the frequency, rate or extent of production of siRNA involved in RNA interference. GO:1903703 enterocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903703 The process in which a relatively unspecialized cell acquires the specialized features of an enterocyte. GO:1903702 esophagus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903702 oesophagus development|esophageal development|gullet development The process whose specific outcome is the progression of an esophagus over time, from its formation to the mature structure. GO:0048307 ferredoxin-nitrite reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048307 MetaCyc:FERREDOXIN--NITRITE-REDUCTASE-RXN|EC:1.7.7.1|RHEA:18041 ammonia:ferredoxin oxidoreductase activity Catalysis of the reaction: NH3 + 2 H2O + 6 oxidized ferredoxin = nitrite + 6 reduced ferredoxin + 7 H+. CL:0001019 CD115-positive monocyte OR common dendritic progenitor biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001019 GO:1903701 substantia propria of cornea development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903701 corneal stroma development|substantia propria development|stroma of cornea development The process whose specific outcome is the progression of a substantia propria of cornea over time, from its formation to the mature structure. GO:0048306 calcium-dependent protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048306 Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in the presence of calcium. GO:1903700 caecum development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903700 blindgut development|caeca development|ceca development|intestinum caecum development|cecum development|blind intestine development|intestinum crassum caecum development|intestinum crassum cecum development The process whose specific outcome is the progression of a caecum over time, from its formation to the mature structure. GO:0048305 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048305 GO:0048304 positive regulation of isotype switching to IgG isotypes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048304 positive regulation of class switching to IgG isotypes|positive regulation of isotype switch recombination to IgG isotypes|up-regulation of isotype switching to IgG isotypes|upregulation of isotype switching to IgG isotypes|up regulation of isotype switching to IgG isotypes|activation of isotype switching to IgG isotypes|positive regulation of class switch recombination to IgG isotypes|stimulation of isotype switching to IgG isotypes Any process that activates or increases the frequency, rate or extent of isotype switching to IgG isotypes. CHEBI:14919 N(6)-lipoyl-L-lysine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_14919 GO:0048303 negative regulation of isotype switching to IgG isotypes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048303 inhibition of isotype switching to IgG isotypes|negative regulation of class switching to IgG isotypes|down regulation of isotype switching to IgG isotypes|downregulation of isotype switching to IgG isotypes|negative regulation of class switch recombination to IgG isotypes|down-regulation of isotype switching to IgG isotypes|negative regulation of isotype switch recombination to IgG isotypes Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgG isotypes. GO:0048302 regulation of isotype switching to IgG isotypes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048302 regulation of class switch recombination to IgG isotypes|regulation of isotype switch recombination to IgG isotypes|regulation of class switching to IgG isotypes Any process that modulates the frequency, rate or extent of isotype switching to IgG isotypes. GO:0048301 positive regulation of isotype switching to IgD isotypes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048301 up-regulation of isotype switching to IgD isotypes|upregulation of isotype switching to IgD isotypes|up regulation of isotype switching to IgD isotypes|activation of isotype switching to IgD isotypes|positive regulation of class switch recombination to IgD isotypes|stimulation of isotype switching to IgD isotypes|positive regulation of class switching to IgD isotypes|positive regulation of isotype switch recombination to IgD isotypes Any process that activates or increases the frequency, rate or extent of isotype switching to IgD isotypes. UBERON:0035128 manus cartilage element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035128 hand cartilage condensation GO:0048300 negative regulation of isotype switching to IgD isotypes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048300 negative regulation of class switching to IgD isotypes|down regulation of isotype switching to IgD isotypes|downregulation of isotype switching to IgD isotypes|negative regulation of class switch recombination to IgD isotypes|down-regulation of isotype switching to IgD isotypes|negative regulation of isotype switch recombination to IgD isotypes|inhibition of isotype switching to IgD isotypes Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgD isotypes. UBERON:0035127 suture of hard palate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035127 palatine suture Any of the sutures of the hard palate UBERON:0035118 material entity in digestive tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035118 ingested material entity|digestive tract contents Any material entity that is located in the digestive tract. This includes undigested food and liquid as well as unexcreted waste products. It also includes other entities such as ingested stones used to aid digestion. Any microbial cells or cell populations are also included. CL:0001012 CD7-negative lymphoid progenitor OR granulocyte monocyte progenitor biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001012 GO:0048309 endoplasmic reticulum inheritance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048309 ER inheritance The partitioning of endoplasmic reticulum between daughter cells at cell division. GO:0048308 organelle inheritance biolink:BiologicalProcess go-plus goslim_yeast|goslim_pir http://purl.obolibrary.org/obo/GO_0048308 The partitioning of organelles between daughter cells at cell division. CHEBI:73296 cholecystokinin antagonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73296 CHEBI:73299 cobalt(II)-factor III(8-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73299 GO:0048310 obsolete nucleus inheritance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048310 cell nucleus inheritance OBSOLETE. The partitioning of nuclei between daughter cells at cell division. SO:0000594 H_ACA_box_snoRNA biolink:SequenceFeature go-plus http://purl.obolibrary.org/obo/SO_0000594 H/ACA box snoRNA|box H/ACA snoRNA|H ACA box snoRNA Members of the box H/ACA family contain an ACA triplet, exactly 3 nt upstream from the 3' end and an H-box in a hinge region that links two structurally similar functional domains of the molecule. Both boxes are important for snoRNA biosynthesis and function. A few box H/ACA snoRNAs are involved in rRNA processing; most others are known or predicted to participate in selection of uridine nucleosides in rRNA to be converted to pseudouridines. Site selection is mediated by direct base pairing of the snoRNA with rRNA through one or both targeting domains. SO:0000593 C_D_box_snoRNA biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000593 C/D box snoRNA|box C/D snoRNA|C D box snoRNA Most box C/D snoRNAs also contain long (>10 nt) sequences complementary to rRNA. Boxes C and D, as well as boxes C' and D', are usually located in close proximity, and form a structure known as the box C/D motif. This motif is important for snoRNA stability, processing, nucleolar targeting and function. A small number of box C/D snoRNAs are involved in rRNA processing; most, however, are known or predicted to serve as guide RNAs in ribose methylation of rRNA. Targeting involves direct base pairing of the snoRNA at the rRNA site to be modified and selection of a rRNA nucleotide a fixed distance from box D or D'. GO:1903719 regulation of I-kappaB phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903719 regulation of IKB phosphorylation|regulation of IkappaB phosphorylation|regulation of inhibitor of NF-kappaB phosphorylation|regulation of inhibitor of kappaB phosphorylation Any process that modulates the frequency, rate or extent of I-kappaB phosphorylation. GO:1903718 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1903718 GO:1903717 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1903717 GO:1903716 guanine transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903716 The process in which guanine is transported across a membrane. GO:1903715 regulation of aerobic respiration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903715 Any process that modulates the frequency, rate or extent of aerobic respiration. UBERON:0035131 auditory ossicle cartilage element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035131 ossicle cartilage condensation UBERON:0035130 auditory ossicle endochondral element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035130 auditory skeletal element|ossicle element|ear ossicles element|ear ossicle element|ossicle element of ear|middle ear ossicle element|ossicular chain element|middle ear skeletal element|ossicle element of inner ear GO:1903714 isoleucine transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903714 The directed movement of isoleucine across a membrane. GO:0048318 axial mesoderm development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048318 The process whose specific outcome is the progression of the axial mesoderm over time, from its formation to the mature structure. The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord. GO:1903713 asparagine transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903713 The directed movement of asparagine across a membrane. UBERON:0035132 auditory ossicle pre-cartilage element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035132 ossicle pre-cartilage condensation CL:0001029 common dendritic progenitor biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001029 common dendritic precursor|pro-DCs|CDP Common dendritic precursor is a hematopoietic progenitor cell that is CD117-low, CD135-positive, CD115-positive and lacks plasma membrane parts for hematopoietic lineage markers. GO:1903712 cysteine transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903712 The directed movement of cysteine across a membrane. GO:0048317 seed morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048317 The process in which the anatomical structures of the seed are generated and organized. GO:0048316 seed development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048316 The process whose specific outcome is the progression of the seed over time, from its formation to the mature structure. A seed is a propagating organ formed in the sexual reproductive cycle of gymnosperms and angiosperms, consisting of a protective coat enclosing an embryo and food reserves. GO:1903711 spermidine transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903711 The process in which spermidine is transported across a membrane. GO:0048315 conidium formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048315 conidia formation|conidia biosynthesis The process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus. GO:1903710 spermine transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903710 The process in which spermine is transported across a membrane. GO:0048314 embryo sac morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048314 female gametophyte morphogenesis The process in which the anatomical structures of the embryo sac are generated and organized. The embryo sac develops from the megaspore in heterosporous plants. GO:0048313 Golgi inheritance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048313 Golgi division|Golgi partitioning The partitioning of Golgi apparatus between daughter cells at cell division. GO:0048312 intracellular distribution of mitochondria biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048312 mitochondria positioning within cell|mitochondrion positioning within cell Any process that establishes the spatial arrangement of mitochondria within the cell. GO:0048311 mitochondrion distribution biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048311 positioning of mitochondria|mitochondrial distribution|distribution of mitochondria Any process that establishes the spatial arrangement of mitochondria between and within cells. CL:0001022 CD115-positive monocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001022 CD115-positive monocyte is a monocyte that is CD115-positive and CD11b-positive. UBERON:0035129 pes cartilage element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035129 foot cartilage condensation CL:0001021 CD34-positive, CD38-positive common lymphoid progenitor biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001021 CD10-positive common lymphoid precursor|CD10-positive common lymphocyte progenitor|CD10-positive common lymphocyte precursor A common lymphoid progenitor that is CD10-positive, CD45RA-positive, CD34-positive and CD38-positive. CL:0001024 CD34-positive, CD38-negative hematopoietic stem cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001024 CD133-positive hematopoietic stem cell CD133-positive hematopoietic stem cell is a hematopoietic stem cell that is CD34-positive, CD90-positive, and CD133-positive. CL:0001023 Kit-positive, CD34-positive common myeloid progenitor biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001023 CD117-positive common myeloid precursor A common myeloid progenitor that is Kit-positive and CD34-positive, Il7ra-negative, and is SCA1-low and Fcgr2-low and Fcgr3-low. CL:0001026 CD34-positive, CD38-positive common myeloid progenitor biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001026 CD71-positive common myeloid precursor A common myeloid progenitor that is CD34-positive, CD38-positive, IL3ra-low, CD10-negative, CD7-negative, CD45RA-negative, and IL-5Ralpha-negative. CL:0001025 Kit-positive, Sca1-positive common lymphoid progenitor biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001025 CD217-positive common lymphocyte precursor|CD217-positive common lymphoid precursor|CD217-positive common lymphocyte progenitor A common lymphoid progenitor that is Kit-low, FLT3-positive, IL7ralpha-positive, and SCA1-low. CL:0001028 CD7-positive lymphoid progenitor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001028 CD7-positive lymphoid precursor CD7-positive lymphoid progenitor cell is a lymphoid progenitor cell that is CD34-positive, CD7-positive and is CD45RA-negative. CL:0001027 CD7-negative lymphoid progenitor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001027 CD7-negative lymphoid precursor CD7-negative lymphoid progenitor cell is a lymphoid progenitor cell that is CD34-positive, CD7-negative and CD45RA-negative. GO:0048319 axial mesoderm morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048319 The process in which the anatomical structures of the axial mesoderm are generated and organized. SO:0000587 group_I_intron biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000587 http://en.wikipedia.org/wiki/Group_I_intron group I intron Group I catalytic introns are large self-splicing ribozymes. They catalyze their own excision from mRNA, tRNA and rRNA precursors in a wide range of organisms. The core secondary structure consists of 9 paired regions (P1-P9). These fold to essentially two domains, the P4-P6 domain (formed from the stacking of P5, P4, P6 and P6a helices) and the P3-P9 domain (formed from the P8, P3, P7 and P9 helices). Group I catalytic introns often have long ORFs inserted in loop regions. SO:0000588 autocatalytically_spliced_intron biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000588 autocatalytically spliced intron|INSDC_qualifier:autocatalytically_spliced_intron|INSDC_feature:ncRNA A self spliced intron. GO:0048321 axial mesodermal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048321 axial mesoderm cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an axial mesoderm cell. GO:0048320 axial mesoderm formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048320 The process that gives rise to the axial mesoderm. This process pertains to the initial formation of the structure from unspecified parts. GO:1903729 regulation of plasma membrane organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903729 regulation of plasma membrane organisation|regulation of plasma membrane organization and biogenesis Any process that modulates the frequency, rate or extent of plasma membrane organization. GO:1903728 luteal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903728 lutein cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a luteal cell. Large luteal cells develop from granulosa cells. Small luteal cells develop from theca cells. GO:1903727 positive regulation of phospholipid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903727 upregulation of phospholipid metabolism|upregulation of phospholipid metabolic process|up regulation of phospholipid metabolism|activation of phospholipid metabolism|positive regulation of phospholipid metabolism|up-regulation of phospholipid metabolic process|activation of phospholipid metabolic process|up-regulation of phospholipid metabolism|up regulation of phospholipid metabolic process Any process that activates or increases the frequency, rate or extent of phospholipid metabolic process. GO:1903726 negative regulation of phospholipid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903726 down regulation of phospholipid metabolic process|inhibition of phospholipid metabolic process|down regulation of phospholipid metabolism|downregulation of phospholipid metabolism|negative regulation of phospholipid metabolism|down-regulation of phospholipid metabolism|down-regulation of phospholipid metabolic process|inhibition of phospholipid metabolism|downregulation of phospholipid metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid metabolic process. GO:1903725 regulation of phospholipid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903725 regulation of phospholipid metabolism Any process that modulates the frequency, rate or extent of phospholipid metabolic process. GO:0048329 negative regulation of axial mesodermal cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048329 inhibition of axial mesodermal cell fate specification|down-regulation of axial mesodermal cell fate specification|downregulation of axial mesodermal cell fate specification|down regulation of axial mesodermal cell fate specification Any process that stops, prevents, or reduces the frequency, rate or extent of axial mesoderm cell fate specification. GO:1903724 positive regulation of centriole elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903724 up regulation of centriole elongation|upregulation of centriole elongation|activation of centriole elongation|up-regulation of centriole elongation Any process that activates or increases the frequency, rate or extent of centriole elongation. GO:1903723 negative regulation of centriole elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903723 downregulation of centriole elongation|down regulation of centriole elongation|inhibition of centriole elongation|down-regulation of centriole elongation Any process that stops, prevents or reduces the frequency, rate or extent of centriole elongation. GO:0048328 regulation of axial mesodermal cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048328 Any process that modulates the frequency, rate or extent of axial mesoderm cell fate specification. GO:1903722 regulation of centriole elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903722 Any process that modulates the frequency, rate or extent of centriole elongation. GO:0048327 axial mesodermal cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048327 axial mesoderm cell fate specification The process in which a cell becomes capable of differentiating autonomously into an axial mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. GO:1903721 positive regulation of I-kappaB phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903721 upregulation of inhibitor of kappaB phosphorylation|up-regulation of IkappaB phosphorylation|up-regulation of IKB phosphorylation|up regulation of I-kappaB phosphorylation|positive regulation of inhibitor of NF-kappaB phosphorylation|upregulation of IkappaB phosphorylation|upregulation of IKB phosphorylation|up regulation of inhibitor of kappaB phosphorylation|up regulation of inhibitor of NF-kappaB phosphorylation|positive regulation of inhibitor of kappaB phosphorylation|activation of inhibitor of kappaB phosphorylation|upregulation of I-kappaB phosphorylation|up regulation of IKB phosphorylation|up regulation of IkappaB phosphorylation|upregulation of inhibitor of NF-kappaB phosphorylation|activation of IKB phosphorylation|positive regulation of IkappaB phosphorylation|activation of IkappaB phosphorylation|positive regulation of IKB phosphorylation|up-regulation of inhibitor of kappaB phosphorylation|up-regulation of I-kappaB phosphorylation|activation of I-kappaB phosphorylation|up-regulation of inhibitor of NF-kappaB phosphorylation|activation of inhibitor of NF-kappaB phosphorylation Any process that activates or increases the frequency, rate or extent of I-kappaB phosphorylation. GO:0048326 positive regulation of axial mesodermal cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048326 upregulation of axial mesodermal cell fate determination|stimulation of axial mesodermal cell fate determination|activation of axial mesodermal cell fate determination|up-regulation of axial mesodermal cell fate determination|up regulation of axial mesodermal cell fate determination Any process that activates or increases the frequency, rate or extent of axial mesoderm cell fate determination. GO:1903720 negative regulation of I-kappaB phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903720 inhibition of IKB phosphorylation|inhibition of IkappaB phosphorylation|down regulation of inhibitor of kappaB phosphorylation|down-regulation of I-kappaB phosphorylation|down-regulation of inhibitor of NF-kappaB phosphorylation|negative regulation of inhibitor of NF-kappaB phosphorylation|downregulation of inhibitor of kappaB phosphorylation|downregulation of I-kappaB phosphorylation|down regulation of IKB phosphorylation|down regulation of IkappaB phosphorylation|downregulation of inhibitor of NF-kappaB phosphorylation|down regulation of I-kappaB phosphorylation|negative regulation of inhibitor of kappaB phosphorylation|down-regulation of inhibitor of kappaB phosphorylation|downregulation of IkappaB phosphorylation|downregulation of IKB phosphorylation|inhibition of I-kappaB phosphorylation|down regulation of inhibitor of NF-kappaB phosphorylation|inhibition of inhibitor of NF-kappaB phosphorylation|inhibition of inhibitor of kappaB phosphorylation|negative regulation of IkappaB phosphorylation|down-regulation of IkappaB phosphorylation|negative regulation of IKB phosphorylation|down-regulation of IKB phosphorylation Any process that stops, prevents or reduces the frequency, rate or extent of I-kappaB phosphorylation. GO:0048325 negative regulation of axial mesodermal cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048325 down-regulation of axial mesodermal cell fate determination|downregulation of axial mesodermal cell fate determination|down regulation of axial mesodermal cell fate determination|inhibition of axial mesodermal cell fate determination Any process that stops, prevents, or reduces the frequency, rate or extent of axial mesoderm cell fate determination. GO:0048324 regulation of axial mesodermal cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048324 Any process that modulates the frequency, rate or extent of axial mesoderm cell fate determination. GO:0048323 axial mesodermal cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048323 axial mesoderm cell fate determination The process in which a cell becomes capable of differentiating autonomously into an axial mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed. GO:0048322 axial mesodermal cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048322 axial mesoderm cell fate commitment The process in which a cell becomes committed to become an axial mesoderm cell. GO:0048332 mesoderm morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048332 The process in which the anatomical structures of the mesoderm are generated and organized. GO:0048331 axial mesoderm structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048331 axial mesoderm structural organisation The process that contributes to the act of creating the structural organization of the axial mesoderm. This process pertains to the physical shaping of a rudimentary structure. GO:0048330 positive regulation of axial mesodermal cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048330 up regulation of axial mesodermal cell fate specification|upregulation of axial mesodermal cell fate specification|stimulation of axial mesodermal cell fate specification|up-regulation of axial mesodermal cell fate specification|activation of axial mesodermal cell fate specification Any process that activates or increases the frequency, rate or extent of axial mesoderm cell fate specification. CL:0001008 Kit and Sca1-positive hematopoietic stem cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001008 Sca1-positive hematopoietic stem cell|LSK stem cell A hematopoietic stem cell that has plasma membrane part Kit-positive, SCA-1-positive, CD150-positive and CD34-negative. GO:0048339 paraxial mesoderm development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048339 The process whose specific outcome is the progression of the paraxial mesoderm over time, from its formation to the mature structure. The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube. GO:0048338 mesoderm structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048338 mesoderm structural organisation The process that contributes to the act of creating the structural organization of the mesoderm. This process pertains to the physical shaping of a rudimentary structure. GO:0048337 positive regulation of mesodermal cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048337 up regulation of mesodermal cell fate specification|upregulation of mesodermal cell fate specification|stimulation of mesodermal cell fate specification|up-regulation of mesodermal cell fate specification|activation of mesodermal cell fate specification Any process that activates or increases the frequency, rate or extent of mesoderm cell fate specification. UBERON:0035159 entire surface of organism biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035159 surface of body Anatomical surface, which is the external surface of the whole body. Examples: There is only one body surface. GO:0048336 positive regulation of mesodermal cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048336 up regulation of mesodermal cell fate determination|upregulation of mesodermal cell fate determination|stimulation of mesodermal cell fate determination|activation of mesodermal cell fate determination|up-regulation of mesodermal cell fate determination Any process that activates or increases the frequency, rate or extent of mesoderm cell fate determination. GO:1903730 regulation of phosphatidate phosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903730 regulation of phosphatidic acid phosphatase activity|regulation of phosphatidate phosphohydrolase activity|regulation of acid phosphatidyl phosphatase activity|regulation of 3-sn-phosphatidate phosphohydrolase activity|regulation of phosphatic acid phosphohydrolase activity|regulation of phosphatic acid phosphatase activity Any process that modulates the frequency, rate or extent of phosphatidate phosphatase activity. GO:0048335 negative regulation of mesodermal cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048335 down-regulation of mesodermal cell fate determination|downregulation of mesodermal cell fate determination|down regulation of mesodermal cell fate determination|inhibition of mesodermal cell fate determination Any process that stops, prevents, or reduces the frequency, rate or extent of mesoderm cell fate determination. GO:0048334 regulation of mesodermal cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048334 Any process that modulates the frequency, rate or extent of mesoderm cell fate determination. GO:0048333 mesodermal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048333 mesoderm cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a mesoderm cell. CHEBI:48218 antiseptic drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48218 CHEBI:48219 disinfectant biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48219 CHEBI:48210 cyclopentafurofurochromene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48210 UBERON:0011234 fibrous membrane of synovial tendon sheath biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011234 UBERON:0011233 synovial membrane of synovial tendon sheath biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011233 synovium Synovial sac which surrounds parts of one or more tendons. Examples: synovial tendon sheath of manual digit 2, radial bursa. CHEBI:87824 methionine sulfone zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87824 CHEBI:87826 L-methionine sulfoximine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87826 CHEBI:87825 N-acetylmethionine sulfone(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87825 CHEBI:87828 N(6)-glutaryl-L-lysine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87828 CHEBI:63856 4,8-dimethylnonanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63856 CHEBI:87827 N-acetyl-L-methionine sulfoximine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87827 CHEBI:87829 2''-O-glutaryl-ADP-D-ribose(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87829 CHEBI:38884 diphenylmethane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38884 UBERON:0001899 epithalamus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001899 epithalamus|ETh Most dorsal part of the thalamus, comprising the pineal gland and habenular nuclei in most vertebrates. In a few vertebrates, it also includes the parietal eye. (Butler and Hodos, Comparative Vertebrate Neuroanatomy, 2nd ed, 2005, pg. 345-346. UBERON:0001898 hypothalamus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001898 Hy|preoptico-hypothalamic region|hypothalamus|preoptico-hypothalamic area A specialized brain region of the ventral diencephalon arising near the end of the segmentation period; the embryonic hypothalamic region will give rise to the posterior pituitary gland as well as a number of brain nuclei. [ZFA]. One of the most important functions of the hypothalamus is to link the nervous system to the endocrine system via the pituitary gland (hypophysis).[Wikipedia]. CHEBI:48206 fucopyranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48206 CHEBI:24250 gibberellin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24250 CHEBI:63862 3'-N-debenzoyltaxol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63862 UBERON:0011222 intra-ocular muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011222 intrinsic muscle of eyeball|intrinsic ocular muscle CHEBI:87810 3-methylmalate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87810 CHEBI:63864 4,8-dimethylnonanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63864 UBERON:0011216 organ system subdivision biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011216 A subdivision of an anatomical system. UBERON:0011215 central nervous system cell part cluster biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011215 cell part cluster of neuraxis|neuraxis layer A multi cell part structure that is part of a central nervous system. CHEBI:63863 3'-N-debenzoyltaxol(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63863 CHEBI:87817 D-ribitol 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87817 CHEBI:63867 N-(hexanoyl)sphing-4-enine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63867 PR:000001808 C/C-C motif small inducible chemokine biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001808 fam:C/C-C chemokine A protein with core architecture consisting of a Small cytokines (intecrine/chemokine), interleukin-8 like (Pfam:PF00048) domain. UBERON:0001888 lateral olfactory stria biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001888 olfactory tract|stria olfactoria lateralis|lateral olfactory tract|tractus olfactorius lateralis|LOT|lateral olfactory tract, body|tractus olfactorius lateralis|lateral olfactory stria|lateral olfactory tract. body White matter tract that contains projections from the olfactory bulb to the olfactory cortex (Maryann Martone). CHEBI:24229 geranylgeraniol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_24229 UBERON:0001887 internal capsule of telencephalon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001887 brain internal capsule|capsula interna|internal capsule radiations|internal capsule White matter regional part of brain which is flanked by nuclear masses, consisting of both afferent and efferent fibers projecting between the cerebral cortex and the brainstem and spinal cord. It consists of three distinct parts: an anterior limb, posterior limb, and genu. (Adapted from MSH by Maryann Martone). UBERON:0001889 trunk of phrenic nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001889 phrenic nerve trunk|phrenic neural trunk NCBITaxon:131221 Streptophytina organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_131221 Charophyta/Embryophyta group|charophyte/embryophyte group CHEBI:24221 3,7-dimethylocta-2,6-dien-1-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_24221 CHEBI:87840 cis-3-hydroxy-D-proline zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87840 UBERON:0011214 nucleus of midbrain tectum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011214 nucleus of tectum|tectal nucleus A neural nucleus that is part of a midbrain tectum. UBERON:0011213 root of vagus nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011213 vagal root|rX|vagus neural rootlet|vagus root|rootlet of vagus nerve|vagus nerve root A root of cranial nerve that is part of a vagus nerve. CHEBI:87842 1,4-naphthoquinone-2-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87842 CHEBI:87841 4-pregnen-20,21-diol-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87841 CHEBI:87844 2-phytyl-1,4-dihydroxynaphthalene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87844 CHEBI:87846 3-hydroxy-O,5-dimethyl-L-tyrosine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87846 CHEBI:38863 trans-decalin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38863 CHEBI:38869 general anaesthetic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38869 CHEBI:38867 anaesthetic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38867 UBERON:0001895 metencephalon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001895 epencephalon-2|epencephalon Rostral segment of the hindbrain that has as its parts the pons (where present) and the cerebellum[WP,modified]. UBERON:0001894 diencephalon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001894 mature diencephalon|betweenbrain|between brain|interbrain|thalamencephalon|DiE|diencephalon The division of the forebrain that develops from the foremost primary cerebral vesicle. UBERON:0001897 dorsal plus ventral thalamus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001897 wider thalamus|Th|thalamus|thalami|thalamencephalon|thalamus opticus Subcortical brain region consisting of paired gray matter bodies in the dorsal diencephalon and forming part of the lateral wall of the third ventricle of the brain. The thalamus represents the major portion of the diencephalon and is commonly divided into cellular aggregates known as nuclear groups.(MeSH). The dorsal topographic division of the interbrain. The macrodissected adult human thalamus was clearly illustrated by Vesalius in 1543 and the term as defined here was introduced by His in 1893. It includes the traditional epithalamus, dorsal thalamus, and ventral thalamus of Herrick (1910, pp. 494, 498). Also see Kuhlenbeck (1927, Ch. 9) and Jones (1985, p. 87). UBERON:0001896 medulla oblongata biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001896 bulbus|medulla oblonzata|bulb|metepencephalon|medulla Organ component of neuraxis that has as its parts the medullary reticular formation, inferior olivary complex and cochlear nuclear complex, among other structures[FMA]. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate[GO]. UBERON:0001891 midbrain biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001891 mesencephalon|MB The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles)[GO]. UBERON:0001890 forebrain biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001890 FB|prosencephalon The most anterior region the brain including both the telencephalon and diencephalon. UBERON:0001893 telencephalon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001893 cerebrum|endbrain|supratentorial region Part of the forebrain consisting of paired olfactory bulbs and cerebral hemispheres. UBERON:0001892 rhombomere biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001892 hindbrain segment|hindbrain neuromere|rhombomeres|future rhombencephalon|segment of hindbrain|hindbrain neuromeres|rhombomere A segment of the developing hindbrain[ZFA]. In the vertebrate embryo, a rhombomere is a transiently divided segment of the developing neural tube, within the hindbrain region (a neuromere) in the area that will eventually become the rhombencephalon. The rhombomeres appear as a series of slightly constricted swellings in the neural tube, caudal to the cephalic flexure.[WP]. CHEBI:73203 N-acylsphingosine 1-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73203 CHEBI:73202 ceramide phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73202 CHEBI:73205 1,2-palmitoyl-sn-glycero-3-phospho-(1'-sn-glycerol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73205 IAO:0100001 term replaced by biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/IAO_0100001 CHEBI:73204 ceramide phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73204 CHEBI:24233 geranylhydroquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_24233 CHEBI:73207 2-hexadecanoyl-1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73207 UBERON:0001876 amygdala biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001876 amygdaloid body|amygdaloid nuclear complex|corpus amygdaloideum|nucleus amygdalae|amygdaloid complex|amygdaloid nucleus|corpus amygdalae|amygdaloid nuclear groups|archistriatum|amygdaloid nuclear group|amygdaloid area Subcortical brain region lying anterior to the hippocampal formation in the temporal lobe and anterior to the temporal horn of the lateral ventricle in some species. It is usually subdivided into several groups. Functionally, it is not considered a unitary structure (MM). CHEBI:73206 1-[(9Z)-octadec-9-enoyl]-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73206 CHEBI:73209 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-icosatetraenoyl)-sn-glycero-3-phospho-D-myo-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73209 CHEBI:73208 2-hexadecanoyl-1-tetradecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73208 CHEBI:24232 geranylgeranylglycerol 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24232 UBERON:0011201 muscle layer of small intestine biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011201 muscular coat of small intestine|tunica muscularis intestini tenuis|small intestine muscularis propria|muscularis externa of small intestine|muscular layer of small intestine|tunica muscularis (intestinum tenue) A muscle layer that is part of a small intestine. CHEBI:87831 N(6)-malonyl-L-lysine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87831 CHEBI:87830 N(6)-succinyl-L-lysine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87830 UBERON:0035237 branch of internal carotid artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035237 subdivision of internal carotid artery|internal carotid arterial subdivision CHEBI:87833 2''-O-malonyl-ADP-D-ribose(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87833 CHEBI:38877 intravenous anaesthetic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38877 CHEBI:87832 2''-O-succinyl-ADP-D-ribose(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87832 CHEBI:63887 1,2-dioleoyl-3-beta-D-galactosylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63887 CHEBI:87835 framycetin(6+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87835 CHEBI:87834 (S)-4-hydroxy-1-pyrroline-2-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87834 CHEBI:87837 ketocytochalasin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87837 CHEBI:87836 2-O-[alpha-D-mannosyl-(1->2)-alpha-D-glucosyl]-D-glycerate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87836 CHEBI:87839 cytochalasin Z16 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87839 CHEBI:87838 iso-precytochalasin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87838 UBERON:0001884 phrenic nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001884 diaphragmatic nerve|phrenic|nervus phrenicus A nerve that arises from the caudal cervical nerves and is primarily the motor nerve of the diaphragm but also sends sensory fibers to the pericardium. PR:000001810 CSF-1/PDGF receptor-type tyrosine-protein kinase biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001810 A protein with core architecture consisting of asignal sequence, 5 Ig-like domains, followed by a transmembrane sequence, followed by a Protein tyrosine kinase domain (Pfam:PF07714). However, only 1-3 of the Ig domains are detected by the Pfam HMMs in most of the sequences. Pfam:PF00047 is most common, but other members of the Ig domain clan, Pfam:PF07679 and Pfam:PF07686 can be identified instead. The fourth Ig domain lacks the disulfide-bonded cysteines. UBERON:0001886 choroid plexus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001886 choroid plexus of cerebral hemisphere|plexus choroideus|plexus choroideus|ventricular choroid plexus|chorioid plexus|CP A network formed by blood vessels and the tela choroidea which secretes CSF into the ventricular spaces. PR:000001812 EGF receptor type tyrosine-protein kinase biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001812 A protein with core architecture consisting of a signal sequence, a Receptor L domain (Pfam:PF01030), a Furin-like cysteine rich region (Pfam:PF00757), another Receptor L domain, a transmembrane domain, and a Protein tyrosine kinase domain (Pfam:PF07714), that may be followed by up to two YLP motifs (Pfam:PF02757). UBERON:0001885 dentate gyrus of hippocampal formation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001885 gyrus dentatus|area dentata|fascia dentata|dentate area (dentate gyrus)|dentate gyrus|hippocampal dentate gyrus|dentate area Part of the hippocampal formation forming a 'V' or 'U' shaped structure with the opening bounded by hippocampal area CA3. It consists of 3 layers from superficial to deep: molecular, granule cell and polymorphic or hilar layer. PR:000001816 HGF/MSP receptor type tyrosine-protein kinase biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001816 A protein with core architecture consisting of a signal sequence, followed by a Sema domain (Pfam:PF01403), three IPT/TIG domains (Pfam:PF01833), a transmembrane region, and a Protein tyrosine kinase domain (Pfam:PF07714). UBERON:0001882 nucleus accumbens biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001882 accumbens nucleus|colliculus of caudate nucleus|nucleus accumbens septi|colliculus nuclei caudati A region of the brain consisting of a collection of neurons located in the forebrain ventral to the caudate and putamen. (caudoputamen in rodent) and continuous with these structures. There is no distinct boundary between the nucleus accumbens and the caudate/putamen, but in rodents, it can be identified by its lack of traversing fiber bundles in comparison to the dorsal striatum. Its principle neuron is the medium spiny neuron. Together with the neostriatum (caudate nucleus and putamen), the nucleus accumbens forms the striatum. CHEBI:73201 17alpha-(N-acetyl-alpha-D-glucosaminyl)estradiol 3-glucuronoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73201 CHEBI:38870 inhalation anaesthetic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38870 CHEBI:73200 1-(5-phospho-beta-D-ribosyl)-ATP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73200 CHEBI:73216 EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73216 CHEBI:73215 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-D-myo-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73215 UBERON:0011272 embryonic skin basal layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011272 basal cell layer of skin|outer epithelium of body NCBITaxon:131209 Zygnemophyceae organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_131209 Gamophyta|Gamophyceae|Conjugatophyceae|gamophytes|Zygnematophyceae CHEBI:73218 1-hexadecanoyl-sn-glycero-3-phospho-D-myo-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73218 UBERON:0011270 dorsal trunk biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011270 dorsal part of trunk|dorsum of trunk|back of trunk|trunk back The part of the trunk that is in the dorsum[cjm]. CHEBI:63891 3-oxopristanic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63891 CHEBI:63894 pivalate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63894 CHEBI:63893 8-hydroxy-alpha-humulene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63893 CHEBI:63892 zerumbone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63892 CHEBI:38846 phenoxyacetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38846 CHEBI:73212 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-D-myo-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73212 CHEBI:73229 1,2-dihexadecanoyl-sn-glycero-3-phospho-D-myo-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73229 CHEBI:24215 gentiobioside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24215 CHEBI:38853 decalin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38853 CHEBI:38856 halophenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38856 PR:000001876 leukemia inhibitory factor receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001876 CD118|LIF receptor|LIF-R|D-factor/LIF receptor|LIFR A protein that is a translation product of the human LIFR gene or a 1:1 ortholog thereof. CHEBI:73223 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phospho-D-myo-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73223 CHEBI:73238 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73238 UBERON:0011250 autopod bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011250 A bone that is part of a autopod region. Note that this incudes the carpal and tarsal bones. CHEBI:38828 nonionic surfactant biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38828 UBERON:0011249 appendicular skeletal system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011249 Subdivision of the skeletal system which consists of the appendicular skeleton plus associated joints. CHEBI:38825 tetrafluoromethane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38825 CHEBI:38824 fluorocarbon biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38824 CHEBI:73234 1-hexadecanoyl-2-[(9Z)-octadec-9-enoyl]-sn-glycero-3-phospho-(1'-sn-glycerol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73234 CHEBI:73246 1,2-dihexadecanoyl-sn-glycerol-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73246 UBERON:0011241 ethmoid region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011241 The most anterior region of the braincase. Provides structural support for peripheral olfactory organ. CHEBI:38831 2-benzofurans biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38831 CHEBI:38830 1-benzofurans biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38830 CHEBI:38836 1-benzothiophenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38836 CHEBI:38835 xanthenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38835 CHEBI:38834 benzofurochromene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38834 CHEBI:14885 prephytoene diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_14885 CHEBI:73241 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73241 PR:000001855 fractalkine biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001855 Cx3c|small-inducible cytokine D1|neurotactin|C-X3-C motif chemokine 1|SCYD1|CX3C membrane-anchored chemokine|CX3CL1|NTT|FKN A protein that is a translation product of the human CX3CL1 gene or a 1:1 ortholog thereof. CHEBI:73240 NF-kappaB inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73240 CHEBI:73242 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73242 CHEBI:73245 cucurbitane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73245 CHEBI:73244 methyl anthranilate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73244 GO:0097475 motor neuron migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097475 The orderly movement of a motor neuron from one site to another. A motor neuron is an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement. UBERON:0001826 nasal cavity mucosa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001826 tunica mucosa nasi|mucosa of nose|tunica mucosa nasalis|mucous membrane of nose|nasal mucosa The mucous membrane that lines the nasal cavity[MP]. GO:0097474 retinal cone cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097474 cone photoreceptor apoptotic process Any apoptotic process in a retinal cone cell, one of the two photoreceptor cell types of the vertebrate retina. GO:0097477 lateral motor column neuron migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097477 The orderly movement of a lateral motor column neuron from one site to another. A lateral motor column neuron is a motor neuron that is generated only on limb levels and send axons into the limb mesenchyme. UBERON:0001828 gingiva biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001828 gum tissue|gum|gums|gingival mucosa The fibrous investing tissue, covered by keratinized epithelium, that immediately surrounds a tooth and is contiguous with its periodontal ligament and with the mucosal tissues of the mouth[Glossary of Periodontal Terms 2001]. UBERON:0001827 secretion of lacrimal gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001827 tear fluid|tear|lacrimal fluid|lacrimal gland secretion|tears|lacrimal secretion Aqueous substance secreted by the lacrimal gland. GO:0097476 spinal cord motor neuron migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097476 The orderly movement of a spinal cord motor neuron from one site to another. A spinal cord motor neuron is a motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement. GO:0097471 mossy fiber rosette biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0097471 NIF_Subcellular:nlx_subcell_091021 cerebellar mossy fiber to granule cell synapse A synapse of a mossy fiber onto the dendrite of a granule cell; each mossy fiber can have up to 50 rosettes. UBERON:0001821 sebaceous gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001821 glandula sebacea|sebaceous follicle|glandula sebaceae A holocrine gland that secretes sebum into the hair follicles, or in hairless areas into ducts.[MP]. GO:0097470 ribbon synapse biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097470 NIF_Subcellular:sao1884931180 synapsis fasciolaris Type of synapse characterized by an electron-dense ribbon, lamella (bar) or spherical body in the presynaptic process cytoplasm. GO:0097473 retinal rod cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097473 rod photoreceptor apoptotic process Any apoptotic process in a retinal rod cell, one of the two photoreceptor cell types of the vertebrate retina. UBERON:0001824 mucosa of larynx biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001824 larynx mucous membrane|laryngeal mucosa|organ mucosa of larynx|larynx mucosa|tunica mucosa laryngis|laryngeal mucous membrane|mucosa of organ of larynx|mucous membrane of larynx|larynx mucosa of organ|larynx organ mucosa The mucous lining of the larynx, which is composed of squamous epithelium in the upper larynx and ciliated columnar epithelium in the lower larynx. GO:0097472 cyclin-dependent protein kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097472 Cyclin-dependent catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP. UBERON:0001823 nasal cartilage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001823 cartilage of nose One of the cartilage structures in the nose that provide form and support[WP]. UBERON:0001829 major salivary gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001829 One of the three largest glands of the oral cavity that secrete most of the saliva, including the parotid, submandibular, and sublingual glands. CHEBI:48299 butane-1,2,3,4-tetrol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48299 GO:0097479 synaptic vesicle localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097479 synaptic vesicle localisation|establishment and maintenance of synaptic vesicle position|establishment and maintenance of synaptic vesicle localization Any process in which a synaptic vesicle or vesicles are transported to, and/or maintained in, a specific location. GO:0097478 leaflet of membrane bilayer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097478 membrane leaflet Any of the two layers of lipid molecules that constitute a membrane. UBERON:0001815 lumbosacral nerve plexus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001815 lumbosacral plexus|plexus lumbosacralis|plexus lumbosacralis An arrangement of nerve fibers, running from the spine that travels to the pelvic appendage where it innervates skin and muscle. GO:0097486 multivesicular body lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097486 The volume enclosed by the outermost membrane of a multivesicular body. GO:0097485 neuron projection guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097485 neurite guidance|neuron process guidance|neuronal cell projection guidance|neuron protrusion guidance The process in which the migration of a neuron projection is directed to a specific target site in response to a combination of attractive and repulsive cues. UBERON:0001814 brachial nerve plexus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001814 plexus brachialis|brachial plexus An arrangement of nerve fibers, running from the spine where it proceeds through the neck then the axilla and into the arm where it innervates skin and muscle. [WP,modified]. UBERON:0001817 lacrimal gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001817 tear gland|glandula praeorbitalis|glandula lacrimalis|preorbital gland|lacrimal-preorbital gland The lacrimal glands are paired almond-shaped glands, located in or near the orbital region, that secrete the aqueous layer of the tear film.[WP]. GO:0097488 multivesicular body, internal vesicle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097488 The lipid bilayer surrounding a multivesicular body internal vesicle. UBERON:0001816 autonomic nerve plexus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001816 plexus visceralis|autonomic plexus|plexus nervosus visceralis|visceral plexus|visceral nerve plexus|plexus autonomicus A nerve plexus that is part of an autonomic nervous system [Automatically generated definition]. GO:0097487 multivesicular body, internal vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097487 A membrane-bounded vesicle wholly contained within a multivesicular body. GO:0097482 muscle cell postsynaptic specialization biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097482 muscle cell postsynaptic density|muscle fiber postsynaptic density A postsynaptic specialization that is part of a neuromuscular junction. GO:0000578 embryonic axis specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000578 embryonic axis determination The establishment, maintenance and elaboration of a pattern along a line or a point in an embryo. UBERON:0001811 conjunctiva biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001811 wall of conjunctival sac|conjunctivas|conjunctivae|tunica conjunctiva the mucous membrane that lines the inner surface of the eyelids and the front of the eyeball GO:0097481 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0097481 UBERON:0001810 nerve plexus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001810 plexus Anatomical junction where subdivisions of two or more neural trees interconnect with one another to form a network through which nerve fibers of the constituent nerve trees become regrouped; together with other nerve plexuses, nerves and ganglia, it constitutes the peripheral nervous system. Examples: cervical nerve plexus, brachial nerve plexus, sacral nerve plexus[FMA]. UBERON:0001813 spinal nerve plexus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001813 spinal nerve plexus|plexus of spinal nerves|somatic nerve plexus|plexus nervorum spinalium an intermingling of fiber fascicles from adjacent spinal nerves to form a network. GO:0097484 dendrite extension biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097484 Long distance growth of a single dendrite involved in cellular development. GO:0097483 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0097483 GO:0097480 establishment of synaptic vesicle localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097480 establishment of synaptic vesicle localisation The directed movement of a synaptic vesicle or vesicles to a specific location. CHEBI:143532 prostaglandin F2alpha-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_143532 UBERON:0001818 tarsal gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001818 Meibomian gland|tarsoconjunctival gland|palpebral gland|glandula tarsales|gland of Meibom A modified lobulated sebaceous gland at the rim of an eyelid, responsible for the supply of meibum. CHEBI:48289 2-O-sulfolactic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48289 CHEBI:48290 (R)-2-O-sulfolactic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48290 CHEBI:48291 (R)-3-sulfolactic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48291 UBERON:0001820 sweat gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001820 sudoriparous gland|glandula sudorifera|sudoriferous gland any of the coil glands of the skin that secrete sweat GO:0097489 multivesicular body, internal vesicle lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097489 The volume enclosed by the membrane of the multivesicular body internal vesicle. UBERON:0001804 capsule of lens biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001804 lens capsule|capsula lentis the elastic, clear, membrane-like structure, that is outer most layer of the lens GO:0097453 mesaxon biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097453 NIF_Subcellular:sao2127666702 mesaxon of Schwann cell Portion of the ensheathing process (either myelin or non-myelin) where the enveloping lips of the ensheathing cell come together so that their apposed plasma membranes run parallel to each other, separated by a cleft 12 nm wide. UBERON:0001803 epithelium of lens biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001803 lens epithelium|lens epithelial tissue|epithelium lentis|epithelial tissue of eye lens|epithelium of eye lens|eye lens epithelium|eye lens epithelial tissue|epithelial tissue of lens A layer of epithelial cells that is part of the eye. GO:0097452 GAIT complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097452 IFN-gamma-activated inhibitor of translation complex|gamma interferon-activated inhibitor of translation complex A protein complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. The complex binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs and suppresses their translation by blocking the recruitment of the 43S ribosomal complex to m7G cap-bound eIF4G. In humans it includes RPL13A, EPRS, SYNCRIP and GAPDH; mouse complexes lack SYNCRIP. CHEBI:48279 serotonergic antagonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48279 UBERON:0001806 sympathetic ganglion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001806 sympathetic part of autonomic division of nervous system ganglion|ganglion sympathicum|sympathetic nervous system ganglion|ganglion of sympathetic nervous system|ganglion sympatheticum|ganglion of sympathetic part of autonomic division of nervous system A ganglion of the sympathetic nervous system. Examples: paravertebral and the prevertebral ganglia, which include the sympathetic chain ganglia, the superior, middle, and inferior cervical ganglia, and the aorticorenal, celiac, and stellate ganglia GO:0097455 spiny bracelet of Nageotte biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097455 NIF_Subcellular:sao937871668 Paranodal terminations of Schwann cells that do not directly contact the paranodal axon membrane. Usually found in thicker myelin. UBERON:0001805 autonomic ganglion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001805 ganglion of visceral nervous system|autonomic nervous system ganglion|ganglion of autonomic nervous system|ganglion autonomicum|visceral nervous system ganglion ganglion that has dendrites that form a junction between autonomic nerves originating from the central nervous system and autonomic nerves innervating their target organs in the periphery. There are two subtypes, sympathetic ganglion and parasympathetic ganglion. GO:0097454 Schwann cell microvillus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097454 NIF_Subcellular:sao1890444066 Small finger-like extension of a Schwann cell that contacts the nodal membrane. UBERON:0001800 sensory ganglion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001800 ganglion sensorium The clusters of neurons in the somatic peripheral nervous system which contain the cell bodies of sensory nerve axons, interneurons and non-neuronal supporting cells. UBERON:0001802 posterior segment of eyeball biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001802 posterior segment of the eye|eye posterior segment|posterior segment eye|posterior eye segment|segmentum posterius bulbi oculi|segmentum posterius (bulbus oculi)|posterior segment of eye any of the parts of the eye that lie in back of, or dorsal to, the lens (but not inclusive) GO:0097451 glial limiting end-foot biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097451 NIF_Subcellular:sao181458425 glial limiting endfoot Terminal process of astrocyte that extends to the surface of the central nervous system. Together, glial limiting end-feet form the glial limiting membrane or glia limitans. GO:0097450 astrocyte end-foot biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097450 NIF_Subcellular:sao388182739 astrocyte endfoot Terminal process of astrocyte abutting non-neuronal surfaces in the brain. UBERON:0001801 anterior segment of eyeball biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001801 segmentum anterius bulbi oculi|anterior segment of eye|anterior segment eye|anterior eye segment|eye anterior segment|segmentum anterius (bulbus oculi)|anterior segment of the eye any of the parts of the eye that lie in front of, or ventral to, the lens (inclusive) CHEBI:48274 tryptamine alkaloid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48274 UBERON:0001808 parasympathetic ganglion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001808 ganglion parasympathicum Ganglion containing neurons that receive innervation from parasympathetic neurons in the central nervous system and subserves parasympathetic functions through innervation of smooth muscle, cardiac muscle and glands. UBERON:0001807 paravertebral ganglion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001807 ganglia of sympathetic trunk|ganglion trunci sympathetici|sympathetic chain ganglia|paravertebral ganglion|paravertebral ganglia|sympathetic chain ganglion|ganglion trunci sympathici|ganglia trunci sympathici|ganglion of sympathetic trunk Trunk ganglion which is part of a bilaterally paired set of sympathetic ganglia located anterior and lateral to the spinal cord. CHEBI:48278 serotonergic drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48278 UBERON:0001809 enteric ganglion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001809 intramural ganglion . CHEBI:143529 (2E)-decenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_143529 GO:0097457 hippocampal mossy fiber biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097457 NIF_Subcellular:nlx_subcell_100312 Axon of dentate gyrus granule cell projecting to hippocampal area CA3, characterized by expansions (mossy fiber expansions) giving the fibers a mossy appearance. These unmyelinated axons were first described by Ramon y Cajal. GO:0097456 terminal loop biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097456 NIF_Subcellular:sao924713546 terminal loop of Schwann cell Portion of myelin-forming Schwann cell consisting of terminal cytoplasmic extensions adhered to the axon at the beginning and end of the myelin sheath. GO:0097459 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0097459 GO:0097458 obsolete neuron part biolink:CellularComponent go-plus goslim_flybase_ribbon|gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0097458 OBSOLETE. Any constituent part of a neuron, the basic cellular unit of nervous tissue. A typical neuron consists of a cell body (often called the soma), an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system. GO:0097464 thorny excrescence biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097464 NIF_Subcellular:nlx_467 Large complex spine protruding from a dendrite. Each excrescence is formed by a cluster of spine heads. GO:0097463 gemmule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097463 NIF_Subcellular:nlx_subcell_1005003 Spine-like process found on some neurons, e.g., periglomerular cells of olfactory cortex. GO:0097466 ubiquitin-dependent glycoprotein ERAD pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097466 misfolded or incompletely synthesized glycoprotein catabolic process|glycoprotein ERAD|gpERAD|ER-associated glycoprotein degradation An ERAD pathway whereby endoplasmic reticulum (ER)-resident glycoproteins are targeted for degradation. Includes differential processing of the glycoprotein sugar chains, retrotranslocation to the cytosol and degradation by the ubiquitin-proteasome pathway. A glycoprotein is a compound in which a carbohydrate component is covalently bound to a protein component. GO:0097465 somatic spine biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097465 NIF_Subcellular:sao2048514053 Spine emanating from the cell soma of a neuron. GO:0097460 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0097460 GO:0097462 Lewy neurite biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097462 NIF_Subcellular:sao601362597 Elongated neuronal process, often with side branches and more than one branching point, described in brains of patients with Parkinson's disease. Lewy neurites stain positively for ubiquitin in brainstem and forebrain regions affected in Parkinson's disease. GO:0097461 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0097461 CHEBI:48262 D-erythrulose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48262 CHEBI:143516 ultra-long-chain 3-oxoacyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_143516 CHEBI:63803 (E)-2,3-didehydropristanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63803 CHEBI:63801 N(alpha)-citryl-N(epsilon)-acetyl-N(epsilon)-hydroxylysine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63801 GO:0097468 programmed cell death in response to reactive oxygen species biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097468 reactive oxygen species-mediated programmed cell death|PCD in response to oxidative stress|programmed cell death in response to oxidative stress|PCD in response to reactive oxygen species|reactive oxygen species-mediated PCD Cell death resulting from activation of endogenous cellular processes and occurring as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals. GO:0097467 type III terminal bouton biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097467 type III terminal button Terminal inflated portion of the axon of a non-glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters at a regulatory synapse. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it. Type III terminal boutons are larger than type II ones. GO:0097469 obsolete cyclin-dependent protein tyrosine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097469 cyclin-dependent protein tyrosine kinase activity OBSOLETE. Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate. This reaction requires the binding of a regulatory cyclin subunit. UBERON:0001869 cerebral hemisphere biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001869 hemispherium cerebri|hemisphere|medial amygdalar nucleus|cerebrum|nucleus medialis amygdalae|hemispheric regions|nucleus amygdaloideus medialis One of two bilateral, largely symmetrical organ subdivisions within the telencephalon which contain the cerebral cortex and cerebral white matter.[FMA] CHEBI:24289 glucosyl-N(6)-isopentenyladenine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24289 UBERON:0001866 sebum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001866 Fatty lubricant matter secreted by sebaceous glands, and made of made of triglyceride oils, wax, squalene, and metabolytes of fat-producing cells[BTO,WP]. UBERON:0001868 skin of chest biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001868 chest skin|anterior thoracic region zone of skin|zone of skin of anterior part of thorax|zone of skin of anterior thoracic region|zone of skin of anterior chest|front of thorax zone of skin|chest zone of skin|zone of skin of pectoral part of chest|zone of skin of anterolateral part of thorax|zone of skin of chest|zone of skin of front of thorax|anterolateral part of thorax zone of skin A zone of skin that is part of a chest [Automatically generated definition]. UBERON:0001867 cartilage of external ear biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001867 external ear cartilage A cartilage that is part of a external ear [Automatically generated definition]. CHEBI:48250 p-menthane-3,8-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48250 CHEBI:24282 glucosyl hydroxycinnamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24282 CHEBI:24281 glucosyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24281 CHEBI:48251 1alpha,3alpha,4beta-p-menthane-3,8-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48251 CHEBI:24280 D-glucosyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_24280 CHEBI:24287 glucosylglycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24287 CHEBI:24286 glucosylglycerol phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24286 CHEBI:63813 adenosine 5'-pentaphosphate(6-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63813 UBERON:0001873 caudate nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001873 nucleus caudatus|caudatus|caudatum|Ammon horn fields Subcortical nucleus of telecephalic origin consisting of an elongated gray mass lying lateral to and bordering the lateral ventricle. It is divided into a head, body and tail in some species. UBERON:0001872 parietal lobe biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001872 lobus parietalis|parietal region|regio parietalis Upper central part of the cerebral hemisphere. (MSH) CHEBI:63818 1-hexadecyl-sn-glycerol 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63818 UBERON:0001875 globus pallidus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001875 paleostriatum|globus pallidus (Burdach)|pallidum|pale body|nucleus pallidus|pallidium Subcortical nucleus, functionally part of the basal ganglia, which consists of two segments the external (or lateral) and internal (or medial) separated by the medial medullary lamina in primates. In rodents, The globus pallidus lateral is separated from the medial segment by the fibers of the internal capsule/cerebral peduncle. UBERON:0001874 putamen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001874 nucleus putamen Subcortical nucleus of telencephalic , which together with the caudate nucleus, forms the striatum. The putamen lies lateral to the internal capsule and medial to the external medullary lamina, and is separated from the caudate nucleus by the fibers of the internal capsule for most of its length, except at its anterior portion. UBERON:0001871 temporal lobe biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001871 temporal cortex|lobus temporalis Lower lateral part of the cerebral hemisphere. (MSH) UBERON:0001870 frontal cortex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001870 frontal neocortex|grey matter of frontal lobe|cortex of frontal lobe|gray matter of frontal lobe|frontal lobe cortex Anterior portion of the neocortex, lying anterior to the central sulcus in humans. It is bounded by the parietal cortex posteriorly and the temporal cortex laterally[NIFSTD,modified]. CHEBI:48249 1r,3c,4t-p-menthane-3,8-diol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48249 CHEBI:24298 glucuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24298 CHEBI:24297 glucuronate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24297 CHEBI:63821 (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63821 CHEBI:63823 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63823 UBERON:0001862 vestibular labyrinth biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001862 labyrinthus vestibularis|vestibular apparatus|vestibular component|inner ear vestibular component The part of the membranous labyrinth that includes the utricle and saccule lodged within the vestibule and the semicircular ducts lodged eccentrically in the corresponding canals. UBERON:0001848 auricular cartilage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001848 pinna cartilage|cartilage of pinna cartilage of the pinna and much of the external ear canal. GO:0097497 blood vessel endothelial cell delamination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097497 The process of negative regulation of cell adhesion that results in blood vessel endothelial cells splitting off from an existing endothelial sheet. CHEBI:24269 glucosamine phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24269 GO:0097496 blood vessel lumen ensheathment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097496 A blood vessel lumenization process that occurs by blood vessel endothelial cells delaminating and aligning along the inner surface of an existing luminal space, extending the open ended lumen, and joining to other blood vessels to form a complete blood vessel. CHEBI:24268 glucooligosaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24268 GO:0097499 protein localization to non-motile cilium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097499 protein localization to nonmotile primary cilium A process in which a protein is transported to, or maintained in, a location within a non-motile cilium. CHEBI:24267 gluconolactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24267 GO:0097498 endothelial tube lumen extension biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097498 Any endothelial tube morphogenesis process by which the tube is increased in length. CHEBI:24266 gluconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24266 UBERON:0001849 membranous labyrinth biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001849 labyrinthus membranaceus Organ with organ cavity which consists of the vestibular labyrinth and the cochlear labyrinth. The membranous labyrinth is lodged within the bony labyrinth and has the same general form; it is, however, considerably smaller and is partly separated from the bony walls by a quantity of fluid, the perilymph.[FMA, WP] GO:0000501 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000501 UBERON:0001844 cochlea biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001844 cochlear duct|cochlear part of bony labyrinth|cochleae|lagenas|cochlear organ|lagena the spiral-shaped bony canal in the inner ear containing the hair cells that transduce sound. Its core component is the Organ of Corti, the sensory organ of hearing, which is distributed along the partition separating fluid chambers in the coiled tapered tube of the cochlea. [WP,modified]. GO:0097493 structural molecule activity conferring elasticity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097493 The action of a molecule that contributes to the structural integrity of a complex or assembly within or outside a cell, providing elasticity and recoiling. GO:0000500 RNA polymerase I upstream activating factor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000500 RNA polymerase I upstream activation factor complex|UAF A complex required for the transcription of rDNA by RNA polymerase I. In yeast the complex consists of Rrrn5p, Rrn9p, Rrn10p, histones H3 and H4, and Uaf30p. UBERON:0001843 lateral semicircular canal biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001843 horizontal semicircular canal|lateral semicircular canals|lateral semicircular duct GO:0097492 sympathetic neuron axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097492 sympathetic neuron axon growth cone guidance|sympathetic neuron axon pathfinding|sympathetic neuron axon chemotaxis The chemotaxis process that directs the migration of a sympathetic neuron axon growth cone to a specific target site in response to a combination of attractive and repulsive cues. GO:0097495 H-NS-Hha complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097495 A trimeric protein complex made up of an H-NS homodimer and an Hha monomer. In Enterobacteriaceae, this complex negatively regulates transcription of a range of genes. UBERON:0001846 internal ear biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001846 otocyst|labyrinth|auris interna|inner ear Complex labyrinthine structure that comprises sensory endorgans specialized for vestibular, auditory, and acoustico-vestibular sensation. GO:0097494 regulation of vesicle size biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097494 Any process that modulates the size of a vesicle. CHEBI:24261 glucocorticoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24261 GO:0097491 sympathetic neuron projection guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097491 sympathetic neuron process guidance|sympathetic neurite guidance|sympathetic neuronal cell projection guidance|sympathetic neuron protrusion guidance The process in which the migration of a sympathetic neuron projection is directed to a specific target site in response to a combination of attractive and repulsive cues. CHEBI:48230 diphthine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48230 GO:0097490 sympathetic neuron projection extension biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097490 sympathetic neuron process extension|sympathetic neuron protrusion extension|sympathetic neurite extension|sympathetic neuronal cell projection extension Long distance growth of a single sympathetic neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite. CHEBI:24265 gluconate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24265 CHEBI:24262 glucoglycerolipid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24262 CHEBI:87802 alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87802 CHEBI:63837 pregn-5-ene-3,20-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63837 CHEBI:87804 3,3',5-trihydroxybibenzyl biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87804 CHEBI:87803 3-(m-hydroxyphenyl)propanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87803 CHEBI:87805 ethionamide S-oxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87805 CHEBI:87808 2-ethylhexyl sulfate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87808 UBERON:0001851 cortex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001851 cortex of organ|cortex Outermost layer of an organ[WP]. GO:0000505 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000505 GO:0000504 obsolete proteasome regulatory particle (sensu Bacteria) biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000504 26S proteasome|proteasome regulatory particle (sensu Bacteria) OBSOLETE. A multisubunit complex that recognizes and unfolds ubiquitinated proteins, and translocates them to the core complex in an ATP dependent manner. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2). GO:0000503 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000503 CHEBI:87809 2-ethylhexanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87809 GO:0000502 proteasome complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0000502 26S proteasome|proteasome A large multisubunit complex which catalyzes protein degradation, found in eukaryotes, archaea and some bacteria. In eukaryotes, this complex consists of the barrel shaped proteasome core complex and one or two associated proteins or complexes that act in regulating entry into or exit from the core. CHEBI:63838 (24S)-7alpha,24-dihydroxycholest-4-en-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63838 GO:0000509 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000509 GO:0000508 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000508 GO:0000507 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000507 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000506 GPI-GnT complex|GPI-N-acetylglucosaminyltransferase complex|GPI-GlcNAc transferase complex An enzyme complex that catalyzes the transfer of GlcNAc from UDP-GlcNAc to an acceptor phosphatidylinositol, the first step in the production of GPI anchors for cell surface proteins. The complex contains PIG-A, PIG-C, PIG-H, PIG-Q, PIG-P, and DPM2 in human, and Eri1p, Gpi1p, Gpi2p, Gpi15p, Gpi19p, and Spt14p in budding yeast. UBERON:0001837 duct of salivary gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001837 secretory duct|salivary gland duct|salivary duct The duct of a salivary gland. UBERON:0001836 saliva biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001836 saliva atomaris|sailva normalis|saliva molecularis|salivary gland secretion A fluid produced in the oral cavity by salivary glands, typically used in predigestion, but also in other functions. CHEBI:24279 glucosinolate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_24279 UBERON:0001839 bony labyrinth biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001839 osseous labyrinth|labyrinthus osseus|osseus labyrinth A system of fluid passages in the inner ear, including both the cochlea, which is part of the auditory system, and the vestibular system, which provides the sense of balance. The bony labyrinth, or osseous labyrinth, is the network of passages with bony walls lined with periosteum. The bony labyrinth is lined with the membranous labyrinth. There is a layer of perilymph between them. The three parts of the bony labyrinth are the vestibule of the ear, the semicircular canals, and the cochlea. The vestibular system is the region of the inner ear where the semicircular canals converge, close to the cochlea (the hearing organ). The vestibular system works with the visual system to keep objects in focus when the head is moving. Joint and muscle receptors also are important in maintaining balance. The brain receives, interprets, and processes the information from these systems that control our balance. [WP,unvetted]. CHEBI:24278 glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24278 UBERON:0001833 lip biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001833 labia oris|lips One of the two fleshy folds which surround the opening of the mouth. UBERON:0001835 lower lip biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001835 lower jaw lip|labium inferius oris Lip that covers the lower portion of the mouth.[TAO]. UBERON:0001834 upper lip biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001834 upper jaw lip|labium superius oris Lip that covers the upper portion of the mouth.[TAO]. CHEBI:24272 glucosaminyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24272 CHEBI:24271 glucosamines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24271 CHEBI:24275 glucosaminylphosphatidylinositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24275 CHEBI:24274 glucosaminylphosphodolichol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24274 CHEBI:24273 glucosaminylamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24273 CHEBI:63844 4-carboxyzymosterol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63844 UBERON:0001840 semicircular canal biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001840 semicircular ducts|ductus semicirculares|scc|canalis semicircularis|semicircular canals One of three half-circular, interconnected tubes located inside each ear[WP]. UBERON:0001842 posterior semicircular canal biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001842 pars superior of labyrinth|posterior semicircular duct|canalis semicircularis posterior|caudal vertical semicircular canal|posterior semicircular canals The posterior semicircular canal is a part of the vestibular system and detects rotations of the head in the sagittal plane. UBERON:0001841 anterior semicircular canal biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001841 anterior semicircular canals|superior semicircular canal|rostral vertical semicircular canal|anterior semicircular duct|canalis semircularis posterior GO:0048464 flower calyx development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048464 The process whose specific outcome is the progression of the flower calyx over time, from its formation to the mature structure. PR:000011194 beta-nerve growth factor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000011194 beta-NGF|NGFB|NGF A neurotrophin that is a translation product of the human NGF gene or a 1:1 ortholog thereof. GO:0048463 carpel structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048463 carpel structural organisation The process that contributes to the act of creating the structural organization of the carpel. This process pertains to the physical shaping of a rudimentary structure. GO:0048462 carpel formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048462 The process that gives rise to the carpel. This process pertains to the initial formation of a structure from unspecified parts. GO:0048461 flower structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048461 flower structural organisation The process that contributes to the act of creating the structural organization of the flower. This process pertains to the physical shaping of a rudimentary structure. GO:1903629 positive regulation of dUTP diphosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903629 up-regulation of dUTP diphosphatase activity|positive regulation of deoxyuridine-triphosphatase activity|positive regulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|up regulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|up regulation of deoxyuridine-triphosphatase activity|up-regulation of desoxyuridine 5'-triphosphatase activity|up-regulation of dUTPase activity|upregulation of dUTP pyrophosphatase activity|activation of dUTPase activity|up regulation of dUTP nucleotidohydrolase activity|activation of desoxyuridine 5'-triphosphatase activity|upregulation of dUTP diphosphatase activity|activation of dUTP nucleotidohydrolase activity|positive regulation of dUTP nucleotidohydrolase activity|upregulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|upregulation of deoxyuridine-triphosphatase activity|up regulation of dUTP pyrophosphatase activity|up regulation of dUTP diphosphatase activity|positive regulation of dUTPase activity|positive regulation of desoxyuridine 5'-triphosphatase activity|positive regulation of dUTP pyrophosphatase activity|activation of dUTP pyrophosphatase activity|up regulation of desoxyuridine 5'-triphosphatase activity|up regulation of dUTPase activity|activation of dUTP diphosphatase activity|up-regulation of dUTP nucleotidohydrolase activity|up-regulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|up-regulation of deoxyuridine-triphosphatase activity|activation of deoxyuridine-triphosphatase activity|activation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|upregulation of dUTPase activity|upregulation of dUTP nucleotidohydrolase activity|upregulation of desoxyuridine 5'-triphosphatase activity|up-regulation of dUTP pyrophosphatase activity Any process that activates or increases the frequency, rate or extent of dUTP diphosphatase activity. GO:0048460 flower formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048460 The process that gives rise to the flower. This process pertains to the initial formation of a structure from unspecified parts. GO:1903628 negative regulation of dUTP diphosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903628 down regulation of dUTP nucleotidohydrolase activity|downregulation of dUTP nucleotidohydrolase activity|downregulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|downregulation of deoxyuridine-triphosphatase activity|down regulation of dUTP pyrophosphatase activity|down regulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|down regulation of deoxyuridine-triphosphatase activity|inhibition of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|inhibition of deoxyuridine-triphosphatase activity|down regulation of dUTP diphosphatase activity|negative regulation of dUTP nucleotidohydrolase activity|negative regulation of desoxyuridine 5'-triphosphatase activity|down-regulation of dUTPase activity|down-regulation of desoxyuridine 5'-triphosphatase activity|negative regulation of dUTPase activity|downregulation of dUTP pyrophosphatase activity|down-regulation of dUTP nucleotidohydrolase activity|downregulation of dUTP diphosphatase activity|inhibition of dUTP nucleotidohydrolase activity|downregulation of desoxyuridine 5'-triphosphatase activity|down-regulation of dUTP pyrophosphatase activity|downregulation of dUTPase activity|negative regulation of dUTP pyrophosphatase activity|down-regulation of dUTP diphosphatase activity|down regulation of desoxyuridine 5'-triphosphatase activity|down regulation of dUTPase activity|inhibition of desoxyuridine 5'-triphosphatase activity|inhibition of dUTPase activity|down-regulation of deoxyuridine-triphosphatase activity|negative regulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|down-regulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|negative regulation of deoxyuridine-triphosphatase activity|inhibition of dUTP pyrophosphatase activity|inhibition of dUTP diphosphatase activity Any process that stops, prevents or reduces the frequency, rate or extent of dUTP diphosphatase activity. GO:1903627 regulation of dUTP diphosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903627 regulation of dUTP nucleotidohydrolase activity|regulation of deoxyuridine-triphosphatase activity|regulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|regulation of dUTP pyrophosphatase activity|regulation of desoxyuridine 5'-triphosphatase activity|regulation of dUTPase activity Any process that modulates the frequency, rate or extent of dUTP diphosphatase activity. GO:1903626 positive regulation of DNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903626 up-regulation of DNA breakdown|positive regulation of DNA catabolism|up regulation of DNA catabolism|upregulation of DNA degradation|up-regulation of DNA catabolic process|upregulation of DNA breakdown|upregulation of DNA catabolic process|upregulation of DNA catabolism|up regulation of DNA degradation|activation of DNA degradation|positive regulation of DNA degradation|up regulation of DNA breakdown|activation of DNA breakdown|positive regulation of DNA breakdown|up-regulation of DNA catabolism|activation of DNA catabolism|up regulation of DNA catabolic process|activation of DNA catabolic process|up-regulation of DNA degradation Any process that activates or increases the frequency, rate or extent of DNA catabolic process. GO:1903625 negative regulation of DNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903625 inhibition of DNA breakdown|inhibition of DNA catabolic process|downregulation of DNA catabolism|down regulation of DNA degradation|down regulation of DNA catabolism|downregulation of DNA degradation|down regulation of DNA breakdown|inhibition of DNA catabolism|down regulation of DNA catabolic process|downregulation of DNA breakdown|downregulation of DNA catabolic process|negative regulation of DNA degradation|down-regulation of DNA degradation|negative regulation of DNA breakdown|down-regulation of DNA breakdown|inhibition of DNA degradation|down-regulation of DNA catabolic process|down-regulation of DNA catabolism|negative regulation of DNA catabolism Any process that stops, prevents or reduces the frequency, rate or extent of DNA catabolic process. GO:1903624 regulation of DNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903624 regulation of DNA catabolism|regulation of DNA degradation|regulation of DNA breakdown Any process that modulates the frequency, rate or extent of DNA catabolic process. GO:1903623 negative regulation of RNA polymerase III activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903623 inhibition of DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter|downregulation of RNA polymerase III activity|down-regulation of RNA polymerase III activity|down regulation of DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter|inhibition of RNA polymerase III activity|downregulation of DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter|negative regulation of DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter|down-regulation of DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter|down regulation of RNA polymerase III activity Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase III activity. GO:1903622 regulation of RNA polymerase III activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903622 regulation of DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter Any process that modulates the frequency, rate or extent of RNA polymerase III activity. GO:0048469 cell maturation biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0048469 functional differentiation A developmental process, independent of morphogenetic (shape) change, that is required for a cell to attain its fully functional state. GO:0048468 cell development biolink:BiologicalProcess go-plus goslim_candida http://purl.obolibrary.org/obo/GO_0048468 terminal differentiation The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. GO:1903621 protein localization to photoreceptor connecting cilium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903621 protein localisation to photoreceptor connecting cilium|protein localization in photoreceptor connecting cilium|protein localisation in photoreceptor connecting cilium A process in which a protein is transported to, or maintained in, a location within a photoreceptor connecting cilium. GO:1903620 positive regulation of transdifferentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903620 upregulation of transdifferentiation|up-regulation of transdifferentiation|activation of transdifferentiation|up regulation of transdifferentiation Any process that activates or increases the frequency, rate or extent of transdifferentiation. GO:0048467 gynoecium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048467 pistil development The process whose specific outcome is the progression of the gynoecium over time, from its formation to the mature structure. The gynoecium is the collective name for the carpels of a flower. GO:0048466 androecium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048466 The process whose specific outcome is the progression of the androecium over time, from its formation to the mature structure. GO:0048465 corolla development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048465 The process whose specific outcome is the progression of the corolla over time, from its formation to the mature structure. GO:0048475 coated membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0048475 A single or double lipid bilayer with any of several different proteinaceous coats that can associate with membranes. Membrane coats include those formed by clathrin plus an adaptor complex, the COPI and COPII complexes. GO:0048474 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048474 GO:0048473 D-methionine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048473 The directed movement of D-methionine into, out of, within, or between cells. GO:0097400 interleukin-17-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097400 interleukin-17-mediated signalling pathway|IL-17-mediated signalling pathway|IL-17-mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-17 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0048472 threonine-phosphate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048472 EC:4.1.1.81|KEGG_REACTION:R06530|RHEA:11492|MetaCyc:4.1.1.81-RXN L-threonine O-3-phosphate carboxy-lyase [(R)-1-aminopropan-2-yl-phosphate-forming]|CobD|L-threonine O-3-phosphate carboxy-lyase activity|L-threonine-O-3-phosphate decarboxylase activity Catalysis of the reaction: O-phospho-L-threonine + H(+) = (R)-1-aminopropan-2-yl phosphate + CO(2). GO:0048471 perinuclear region of cytoplasm biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0048471 Cytoplasm situated near, or occurring around, the nucleus. GO:1903639 regulation of gastrin-induced gastric acid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903639 Any process that modulates the frequency, rate or extent of gastrin-induced gastric acid secretion. GO:0048470 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048470 GO:1903638 positive regulation of protein insertion into mitochondrial outer membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903638 up regulation of protein transport into mitochondrial outer membrane|positive regulation of protein transport into mitochondrial outer membrane|activation of protein transport into mitochondrial outer membrane|up regulation of mitochondrial outer membrane protein import|upregulation of protein import into mitochondrial outer membrane|activation of mitochondrial outer membrane protein import|positive regulation of mitochondrial outer membrane protein import|up-regulation of protein insertion into mitochondrial outer membrane|positive regulation of protein import into mitochondrial outer membrane|up-regulation of protein import into mitochondrial outer membrane|up-regulation of protein transport into mitochondrial outer membrane|activation of protein import into mitochondrial outer membrane|upregulation of protein insertion into mitochondrial outer membrane|up-regulation of mitochondrial outer membrane protein import|upregulation of protein transport into mitochondrial outer membrane|up regulation of protein import into mitochondrial outer membrane|upregulation of mitochondrial outer membrane protein import|up regulation of protein insertion into mitochondrial outer membrane|activation of protein insertion into mitochondrial outer membrane Any process that activates or increases the frequency, rate or extent of protein insertion into mitochondrial outer membrane. GO:1903637 negative regulation of protein insertion into mitochondrial outer membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903637 down-regulation of protein insertion into mitochondrial outer membrane|down regulation of protein import into mitochondrial outer membrane|downregulation of mitochondrial outer membrane protein import|inhibition of protein import into mitochondrial outer membrane|negative regulation of protein import into mitochondrial outer membrane|negative regulation of protein transport into mitochondrial outer membrane|down-regulation of protein transport into mitochondrial outer membrane|inhibition of protein insertion into mitochondrial outer membrane|negative regulation of mitochondrial outer membrane protein import|down-regulation of mitochondrial outer membrane protein import|inhibition of protein transport into mitochondrial outer membrane|inhibition of mitochondrial outer membrane protein import|down regulation of protein insertion into mitochondrial outer membrane|down-regulation of protein import into mitochondrial outer membrane|downregulation of protein insertion into mitochondrial outer membrane|down regulation of protein transport into mitochondrial outer membrane|downregulation of protein import into mitochondrial outer membrane|down regulation of mitochondrial outer membrane protein import|downregulation of protein transport into mitochondrial outer membrane Any process that stops, prevents or reduces the frequency, rate or extent of protein insertion into mitochondrial outer membrane. GO:1903636 regulation of protein insertion into mitochondrial outer membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903636 regulation of mitochondrial outer membrane protein import|regulation of protein import into mitochondrial outer membrane|regulation of protein transport into mitochondrial outer membrane Any process that modulates the frequency, rate or extent of protein insertion into mitochondrial outer membrane. GO:1903635 positive regulation of leucine-tRNA ligase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903635 up regulation of leucine-tRNA ligase activity|up regulation of leucyl-transfer ribonucleate synthetase activity|positive regulation of leucine translase activity|activation of L-leucine:tRNALeu ligase (AMP-forming)|up-regulation of L-leucine:tRNALeu ligase (AMP-forming)|activation of leucyl-transfer ribonucleic acid synthetase activity|up-regulation of leucyl-transfer ribonucleic acid synthetase activity|up regulation of leucine translase activity|upregulation of leucyl-tRNA synthetase activity|upregulation of leucyl-transfer RNA synthetase activity|upregulation of leucine-tRNA synthetase activity|upregulation of leucine-tRNA ligase activity|upregulation of leucyl-transfer ribonucleate synthetase activity|positive regulation of L-leucine:tRNALeu ligase (AMP-forming)|positive regulation of leucyl-transfer ribonucleic acid synthetase activity|upregulation of leucine translase activity|up regulation of L-leucine:tRNALeu ligase (AMP-forming)|up regulation of leucyl-tRNA synthetase activity|up regulation of leucyl-transfer ribonucleic acid synthetase activity|up regulation of leucyl-transfer RNA synthetase activity|activation of leucyl-tRNA synthetase activity|up-regulation of leucine-tRNA synthetase activity|positive regulation of leucyl-tRNA synthetase activity|activation of leucine-tRNA synthetase activity|activation of leucyl-transfer RNA synthetase activity|positive regulation of leucyl-transfer RNA synthetase activity|up-regulation of leucine-tRNA ligase activity|activation of leucine-tRNA ligase activity|up-regulation of leucyl-transfer ribonucleate synthetase activity|activation of leucyl-transfer ribonucleate synthetase activity|up-regulation of leucine translase activity|activation of leucine translase activity|upregulation of L-leucine:tRNALeu ligase (AMP-forming)|upregulation of leucyl-transfer ribonucleic acid synthetase activity|up-regulation of leucyl-tRNA synthetase activity|positive regulation of leucine-tRNA synthetase activity|up-regulation of leucyl-transfer RNA synthetase activity|up regulation of leucine-tRNA synthetase activity|positive regulation of leucyl-transfer ribonucleate synthetase activity Any process that activates or increases the frequency, rate or extent of leucine-tRNA ligase activity. GO:1903634 negative regulation of leucine-tRNA ligase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903634 downregulation of leucine-tRNA synthetase activity|downregulation of leucine-tRNA ligase activity|downregulation of leucyl-transfer ribonucleate synthetase activity|down regulation of leucine-tRNA synthetase activity|downregulation of leucine translase activity|down regulation of leucine-tRNA ligase activity|down regulation of leucyl-transfer ribonucleate synthetase activity|inhibition of leucine-tRNA synthetase activity|down-regulation of L-leucine:tRNALeu ligase (AMP-forming)|negative regulation of L-leucine:tRNALeu ligase (AMP-forming)|inhibition of leucine-tRNA ligase activity|down regulation of leucyl-tRNA synthetase activity|inhibition of leucyl-transfer ribonucleate synthetase activity|down regulation of leucyl-transfer RNA synthetase activity|negative regulation of leucyl-transfer ribonucleic acid synthetase activity|down-regulation of leucyl-transfer ribonucleic acid synthetase activity|down regulation of leucine translase activity|downregulation of leucyl-tRNA synthetase activity|inhibition of leucine translase activity|downregulation of leucyl-transfer RNA synthetase activity|downregulation of L-leucine:tRNALeu ligase (AMP-forming)|downregulation of leucyl-transfer ribonucleic acid synthetase activity|down-regulation of leucyl-tRNA synthetase activity|negative regulation of leucyl-tRNA synthetase activity|down regulation of L-leucine:tRNALeu ligase (AMP-forming)|down regulation of leucyl-transfer ribonucleic acid synthetase activity|down-regulation of leucyl-transfer RNA synthetase activity|negative regulation of leucyl-transfer RNA synthetase activity|inhibition of L-leucine:tRNALeu ligase (AMP-forming)|inhibition of leucyl-transfer ribonucleic acid synthetase activity|down-regulation of leucine-tRNA synthetase activity|negative regulation of leucine-tRNA synthetase activity|down-regulation of leucine-tRNA ligase activity|negative regulation of leucyl-transfer ribonucleate synthetase activity|down-regulation of leucyl-transfer ribonucleate synthetase activity|inhibition of leucyl-tRNA synthetase activity|inhibition of leucyl-transfer RNA synthetase activity|down-regulation of leucine translase activity|negative regulation of leucine translase activity Any process that stops, prevents or reduces the frequency, rate or extent of leucine-tRNA ligase activity. GO:1903633 regulation of leucine-tRNA ligase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903633 regulation of leucine-tRNA synthetase activity|regulation of leucyl-transfer ribonucleate synthetase activity|regulation of leucine translase activity|regulation of leucyl-tRNA synthetase activity|regulation of leucyl-transfer RNA synthetase activity|regulation of L-leucine:tRNALeu ligase (AMP-forming)|regulation of leucyl-transfer ribonucleic acid synthetase activity Any process that modulates the frequency, rate or extent of leucine-tRNA ligase activity. GO:1903632 positive regulation of aminoacyl-tRNA ligase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903632 upregulation of aminoacyl-tRNA synthetase activity|upregulation of aminoacyl-tRNA ligase activity|positive regulation of aminoacyl-tRNA synthetase auxiliary protein activity|up regulation of aminoacyl-tRNA synthetase auxiliary protein activity|up-regulation of aminoacyl-tRNA synthetase activity|activation of aminoacyl-tRNA synthetase activity|up-regulation of aminoacyl-tRNA ligase activity|activation of aminoacyl-tRNA ligase activity|upregulation of aminoacyl-tRNA synthetase auxiliary protein activity|positive regulation of aminoacyl-tRNA synthetase activity|up regulation of aminoacyl-tRNA synthetase activity|up-regulation of aminoacyl-tRNA synthetase auxiliary protein activity|up regulation of aminoacyl-tRNA ligase activity|activation of aminoacyl-tRNA synthetase auxiliary protein activity Any process that activates or increases the frequency, rate or extent of aminoacyl-tRNA ligase activity. GO:0048479 style development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048479 The process whose specific outcome is the progression of the style over time, from its formation to the mature structure. The style is an elongated part of a carpel, or group of fused carpels, and it lies between the ovary and the stigma. GO:1903631 negative regulation of aminoacyl-tRNA ligase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903631 inhibition of aminoacyl-tRNA ligase activity|downregulation of aminoacyl-tRNA synthetase auxiliary protein activity|down regulation of aminoacyl-tRNA synthetase auxiliary protein activity|down-regulation of aminoacyl-tRNA synthetase activity|negative regulation of aminoacyl-tRNA synthetase activity|down-regulation of aminoacyl-tRNA ligase activity|inhibition of aminoacyl-tRNA synthetase auxiliary protein activity|downregulation of aminoacyl-tRNA synthetase activity|downregulation of aminoacyl-tRNA ligase activity|down regulation of aminoacyl-tRNA synthetase activity|inhibition of aminoacyl-tRNA synthetase activity|down regulation of aminoacyl-tRNA ligase activity|negative regulation of aminoacyl-tRNA synthetase auxiliary protein activity|down-regulation of aminoacyl-tRNA synthetase auxiliary protein activity Any process that stops, prevents or reduces the frequency, rate or extent of aminoacyl-tRNA ligase activity. GO:0048478 replication fork protection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048478 replication fork stabilization|replication fork maintenance Any process that prevents the collapse of stalled replication forks. GO:1903630 regulation of aminoacyl-tRNA ligase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903630 regulation of aminoacyl-tRNA synthetase auxiliary protein activity|regulation of aminoacyl-tRNA synthetase activity Any process that modulates the frequency, rate or extent of aminoacyl-tRNA ligase activity. GO:0048477 oogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048477 Wikipedia:Oogenesis ovum development The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster. GO:0048476 Holliday junction resolvase complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0048476 Mus81-Eme2 complex|resolvasome|Mus81-Eme1 complex|Mus81-Eme1 holliday resolvase complex|Mus81-Eme2 holliday resolvase complex An endodeoxyribonuclease complex that resolves the 4-way DNA intermediates of a Holliday junction into two separate duplex DNA molecules. Can be branch-migration associated. GO:0097409 glial cytoplasmic inclusion biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097409 NIF_Subcellular:nlx_subcell_20090703 GCI|Papp-Lantos body Non-membrane-bound cytoplasmic inclusions composed of 10-40 nm granule-coated fibrils. These inclusions have an abnormal accumulation of alpha-synuclein protein and are found in association with multiple system atrophy. GO:0097406 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0097406 GO:0097405 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0097405 GO:0097408 fibrillary inclusion biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097408 NIF_Subcellular:sao967812059 Cellular inclusion consisting of circular areas filled with fine slender filaments about 10 nanometers in diameter, delimited by a wall of varying complexity (either a single continuous membrane or a tubular network consisting of a fine filamentous material giving the wall a honeycomb appearance). Fibrillary inclusions are found in the cytoplasm of giant cells of Dieters in the lateral vestibular nucleus of the rat; similar structures have been described in the ventral cochlear nucleus, spinal cord, and substantia nigra. GO:0097407 Bunina body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097407 NIF_Subcellular:nlx_subcell_20090101 Small granular inclusions (about 1-3 microns in diameter) found in the anterior horn cells, and appearing either singly or in a group. Sometimes they are arranged in small beaded chains. Bunina bodies express cystatin C and consist of electron-dense amorphous material that contains tubules or vesicular structures. The amorphous material frequently includes a cytoplasmic island containing neurofilaments and other micro-organelles. GO:0097402 neuroblast migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097402 The orderly movement of a neuroblast from one site to another, often during the development of a multicellular organism or multicellular structure. A neuroblast is any cell that will divide and give rise to a neuron. GO:0097401 synaptic vesicle lumen acidification biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0097401 synaptic vesicle lumen pH reduction|synaptic vesicle proton loading The acidification of the synaptic vesicle lumen via transport of protons into the vesicle. The resulting electrochemical gradient powers neurotransmitter loading. GO:0097404 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0097404 GO:0097403 cellular response to raffinose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097403 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a raffinose stimulus. GO:0048486 parasympathetic nervous system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048486 The process whose specific outcome is the progression of the parasympathetic nervous system over time, from its formation to the mature structure. The parasympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia. GO:0048485 sympathetic nervous system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048485 The process whose specific outcome is the progression of the sympathetic nervous system over time, from its formation to the mature structure. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter. GO:0048484 enteric nervous system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048484 The process whose specific outcome is the progression of the enteric nervous system over time, from its formation to the mature structure. The enteric nervous system is composed of two ganglionated neural plexuses in the gut wall which form one of the three major divisions of the autonomic nervous system. The enteric nervous system innervates the gastrointestinal tract, the pancreas, and the gall bladder. It contains sensory neurons, interneurons, and motor neurons. Thus the circuitry can autonomously sense the tension and the chemical environment in the gut and regulate blood vessel tone, motility, secretions, and fluid transport. The system is itself governed by the central nervous system and receives both parasympathetic and sympathetic innervation. GO:0048483 autonomic nervous system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048483 The process whose specific outcome is the progression of the autonomic nervous system over time, from its formation to the mature structure. The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands. GO:0048482 plant ovule morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048482 The process in which the anatomical structures of the ovule are generated and organized. The ovule is the structure in seed plants enclosing the female gametophyte, and is composed of the nucellus, one or two integuments, and the funiculus; it develops into the seed. GO:0048481 plant ovule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048481 The process whose specific outcome is the progression of the ovule over time, from its formation to the mature structure. The ovule is the structure in seed plants enclosing the female gametophyte, and is composed of the nucellus, one or two integuments, and the funiculus; it develops into the seed. GO:1903649 regulation of cytoplasmic transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903649 regulation of cytoplasmic streaming Any process that modulates the frequency, rate or extent of cytoplasmic transport. GO:0048480 stigma development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048480 The process whose specific outcome is the progression of the stigma over time, from its formation to the mature structure. The stigma is the pollen-receptive surface of a carpel or group of fused carpels, usually sticky. GO:1903648 positive regulation of chlorophyll catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903648 upregulation of chlorophyll breakdown|positive regulation of chlorophyll catabolism|up regulation of chlorophyll catabolism|upregulation of chlorophyll catabolic process|up regulation of chlorophyll degradation|activation of chlorophyll degradation|positive regulation of chlorophyll degradation|up regulation of chlorophyll breakdown|positive regulation of chlorophyll breakdown|activation of chlorophyll breakdown|upregulation of chlorophyll catabolism|up regulation of chlorophyll catabolic process|activation of chlorophyll catabolic process|up-regulation of chlorophyll degradation|up-regulation of chlorophyll catabolism|up-regulation of chlorophyll breakdown|activation of chlorophyll catabolism|upregulation of chlorophyll degradation|up-regulation of chlorophyll catabolic process Any process that activates or increases the frequency, rate or extent of chlorophyll catabolic process. GO:1903647 negative regulation of chlorophyll catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903647 negative regulation of chlorophyll catabolism|down-regulation of chlorophyll catabolism|down regulation of chlorophyll degradation|downregulation of chlorophyll degradation|down regulation of chlorophyll breakdown|downregulation of chlorophyll breakdown|down regulation of chlorophyll catabolic process|downregulation of chlorophyll catabolism|downregulation of chlorophyll catabolic process|down regulation of chlorophyll catabolism|negative regulation of chlorophyll degradation|down-regulation of chlorophyll degradation|inhibition of chlorophyll catabolism|negative regulation of chlorophyll breakdown|down-regulation of chlorophyll breakdown|inhibition of chlorophyll degradation|down-regulation of chlorophyll catabolic process|inhibition of chlorophyll breakdown|inhibition of chlorophyll catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of chlorophyll catabolic process. GO:1903646 positive regulation of chaperone-mediated protein folding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903646 upregulation of chaperone-mediated protein folding|up-regulation of chaperone-mediated protein folding|activation of chaperone-mediated protein folding|up regulation of chaperone-mediated protein folding Any process that activates or increases the frequency, rate or extent of chaperone-mediated protein folding. GO:1903645 negative regulation of chaperone-mediated protein folding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903645 downregulation of chaperone-mediated protein folding|down regulation of chaperone-mediated protein folding|inhibition of chaperone-mediated protein folding|down-regulation of chaperone-mediated protein folding Any process that stops, prevents or reduces the frequency, rate or extent of chaperone-mediated protein folding. GO:1903644 regulation of chaperone-mediated protein folding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903644 Any process that modulates the frequency, rate or extent of chaperone-mediated protein folding. GO:1903643 positive regulation of recombination hotspot binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903643 up-regulation of recombination hotspot binding|upregulation of DNA binding, recombination hotspot|upregulation of recombination hotspot binding|activation of DNA binding, recombination hotspot|up-regulation of DNA binding, recombination hotspot|up regulation of recombination hotspot binding|activation of recombination hotspot binding|positive regulation of DNA binding, recombination hotspot|up regulation of DNA binding, recombination hotspot Any process that activates or increases the frequency, rate or extent of recombination hotspot binding. GO:1903642 regulation of recombination hotspot binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903642 regulation of DNA binding, recombination hotspot Any process that modulates the frequency, rate or extent of recombination hotspot binding. GO:0048489 synaptic vesicle transport biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0048489 synaptic vesicle fusion|synaptic vesicle trafficking|synaptic vesicle fission The directed movement of synaptic vesicles. GO:0048488 synaptic vesicle endocytosis biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0048488 synaptic vesicle retrieval A vesicle-mediated transport process, in which the synaptic vesicle membrane constituents are retrieved from the presynaptic membrane on the axon terminal after neurotransmitter secretion by exocytosis. Synaptic vesicle endocytosis can occur via clathrin-dependent and clathrin-independent mechanisms. GO:1903641 positive regulation of gastrin-induced gastric acid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903641 up-regulation of gastrin-induced gastric acid secretion|activation of gastrin-induced gastric acid secretion|up regulation of gastrin-induced gastric acid secretion|upregulation of gastrin-induced gastric acid secretion Any process that activates or increases the frequency, rate or extent of gastrin-induced gastric acid secretion. GO:0048487 beta-tubulin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048487 beta tubulin binding Interacting selectively and non-covalently with the microtubule constituent protein beta-tubulin. GO:1903640 negative regulation of gastrin-induced gastric acid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903640 down-regulation of gastrin-induced gastric acid secretion|downregulation of gastrin-induced gastric acid secretion|down regulation of gastrin-induced gastric acid secretion|inhibition of gastrin-induced gastric acid secretion Any process that stops, prevents or reduces the frequency, rate or extent of gastrin-induced gastric acid secretion. GO:1903650 negative regulation of cytoplasmic transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903650 downregulation of cytoplasmic transport|downregulation of cytoplasmic streaming|down-regulation of cytoplasmic transport|down-regulation of cytoplasmic streaming|negative regulation of cytoplasmic streaming|inhibition of cytoplasmic transport|inhibition of cytoplasmic streaming|down regulation of cytoplasmic transport|down regulation of cytoplasmic streaming Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic transport. PR:000011167 nuclear factor of activated T-cells, cytoplasmic 4 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000011167 NFATC4|NFATc4|NF-ATc4|NF-AT3|T-cell transcription factor NFAT3|NFAT3 A protein that is a translation product of the human NFATC4 gene or a 1:1 ortholog thereof. PR:000011166 nuclear factor of activated T-cells, cytoplasmic 3 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000011166 NFATc3|NFATC3|NF-ATc3|NFATx|NF-AT4|T-cell transcription factor NFAT4|NFAT4 A protein that is a translation product of the human NFATC3 gene or a 1:1 ortholog thereof. PR:000011164 nuclear factor of activated T-cells, cytoplasmic 2 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000011164 NFATc2|NFATC2|NF-ATc2|NFAT pre-existing subunit|NF-ATp|T-cell transcription factor NFAT1|NFAT1|NFATP A protein that is a translation product of the human NFATC2 gene or a 1:1 ortholog thereof. CHEBI:143593 beta-galactosylceramide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_143593 GO:0048497 maintenance of floral organ identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048497 The process in which the identity of a floral organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized. GO:0048496 maintenance of animal organ identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048496 The process in which the identity of an animal organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized. GO:0048495 Roundabout binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048495 Roundabout receptor binding Interacting selectively and non-covalently with the Roundabout (ROBO) receptor, a transmembrane receptor. GO:0048494 chromatophore ribulose bisphosphate carboxylase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0048494 RubisCO complex A complex, located in the chromatophore, containing either both large and small subunits or just small subunits which carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate. GO:0048493 plasma membrane-derived thylakoid ribulose bisphosphate carboxylase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0048493 ribulose bisphosphate carboxylase complex|plasma membrane ribulose bisphosphate carboxylase complex|RubisCO complex A complex, located in the plasma membrane-derived thylakoid, containing either both large and small subunits or just small subunits. It carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate. GO:0048492 ribulose bisphosphate carboxylase complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0048492 RubisCO complex A complex containing either both large and small subunits or just small subunits which carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate. GO:0048491 retrograde synaptic vesicle transport biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0048491 retrograde axonal transport of synaptic vesicle The directed movement of synaptic vesicle along axonal microtubules from the presynapse to the cell body. GO:0048490 anterograde synaptic vesicle transport biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0048490 anterograde axonal transport of synaptic vesicle The directed movement of synaptic vesicle along axonal microtubules from the cell body to the presynapse. GO:1903659 regulation of complement-dependent cytotoxicity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903659 Any process that modulates the frequency, rate or extent of complement-dependent cytotoxicity. GO:1903658 positive regulation of type IV pilus biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903658 activation of type IV pilus biogenesis|up-regulation of type IV fimbria biogenesis|up regulation of type IV pilus biosynthesis|positive regulation of type IV fimbrial biogenesis|activation of type IV fimbrial biogenesis|activation of type IV fimbria biogenesis|upregulation of type IV fimbrium biogenesis|up-regulation of type 4 pilus biogenesis|positive regulation of TFP biogenesis|up-regulation of type IV fimbriae biogenesis|positive regulation of type IV fimbria assembly|up regulation of TFP biogenesis|up-regulation of type IV fimbrial assembly|up regulation of type IV fimbrium assembly|up regulation of type IV fimbria assembly|activation of type IV fimbrium assembly|upregulation of type IV fimbriae assembly|positive regulation of type IV fimbrium assembly|upregulation of type IV pilus biosynthesis|positive regulation of type IV fimbria biogenesis|up-regulation of type IV fimbrial biogenesis|up regulation of type IV fimbrium biogenesis|up regulation of type IV pilus biogenesis|up regulation of type IV fimbria biogenesis|upregulation of type 4 pilus biogenesis|upregulation of type IV fimbriae biogenesis|positive regulation of type IV fimbrium biogenesis|activation of type IV fimbrium biogenesis|upregulation of type IV fimbrial assembly|upregulation of TFP biogenesis|upregulation of type IV fimbria assembly|up regulation of type IV fimbriae assembly|up-regulation of type IV pilus biosynthesis|up-regulation of type IV fimbrium assembly|positive regulation of type IV fimbriae assembly|activation of type IV fimbriae assembly|activation of type IV pilus biosynthesis|upregulation of type IV fimbrial biogenesis|upregulation of type IV pilus biogenesis|up regulation of type 4 pilus biogenesis|upregulation of type IV fimbria biogenesis|up regulation of type IV fimbriae biogenesis|up regulation of type IV fimbrial assembly|activation of type 4 pilus biogenesis|up-regulation of TFP biogenesis|up-regulation of type IV fimbrium biogenesis|positive regulation of type 4 pilus biogenesis|activation of TFP biogenesis|positive regulation of type IV fimbriae biogenesis|up-regulation of type IV fimbria assembly|activation of type IV fimbriae biogenesis|positive regulation of type IV fimbrial assembly|activation of type IV fimbria assembly|activation of type IV fimbrial assembly|upregulation of type IV fimbrium assembly|positive regulation of type IV pilus biosynthesis|up-regulation of type IV pilus biogenesis|up-regulation of type IV fimbriae assembly|up regulation of type IV fimbrial biogenesis Any process that activates or increases the frequency, rate or extent of type IV pilus biogenesis. GO:1903657 negative regulation of type IV pilus biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903657 down-regulation of TFP biogenesis|negative regulation of TFP biogenesis|down-regulation of type IV fimbria assembly|negative regulation of type IV fimbria assembly|downregulation of type IV pilus biosynthesis|downregulation of type IV fimbrium assembly|inhibition of type 4 pilus biogenesis|inhibition of type IV fimbriae biogenesis|negative regulation of type IV fimbrial biogenesis|down regulation of type IV fimbrium biogenesis|down-regulation of type IV fimbrial biogenesis|inhibition of type IV fimbrial assembly|down-regulation of type IV pilus biogenesis|negative regulation of type IV fimbria biogenesis|down-regulation of type IV fimbria biogenesis|down regulation of type IV pilus biosynthesis|inhibition of type IV pilus biosynthesis|downregulation of type IV fimbrium biogenesis|downregulation of TFP biogenesis|downregulation of type IV fimbria assembly|inhibition of type IV fimbrial biogenesis|down regulation of type IV fimbriae assembly|down-regulation of type IV fimbrium assembly|negative regulation of type IV fimbrium assembly|down regulation of TFP biogenesis|down regulation of type IV fimbria assembly|inhibition of TFP biogenesis|inhibition of type IV fimbria assembly|downregulation of type IV pilus biogenesis|downregulation of type IV fimbriae assembly|downregulation of type IV fimbria biogenesis|down regulation of type 4 pilus biogenesis|down regulation of type IV fimbriae biogenesis|inhibition of type IV fimbrium assembly|down-regulation of type IV fimbrium biogenesis|down regulation of type IV fimbrial assembly|negative regulation of type IV fimbrium biogenesis|down regulation of type IV pilus biogenesis|inhibition of type IV pilus biogenesis|downregulation of type 4 pilus biogenesis|down regulation of type IV fimbria biogenesis|downregulation of type IV fimbriae biogenesis|inhibition of type IV fimbria biogenesis|downregulation of type IV fimbrial assembly|negative regulation of type IV fimbriae assembly|inhibition of type IV fimbrium biogenesis|down-regulation of type IV fimbriae assembly|down regulation of type IV fimbrial biogenesis|negative regulation of type IV pilus biosynthesis|down-regulation of type IV pilus biosynthesis|downregulation of type IV fimbrial biogenesis|negative regulation of type 4 pilus biogenesis|down-regulation of type 4 pilus biogenesis|negative regulation of type IV fimbriae biogenesis|down-regulation of type IV fimbriae biogenesis|inhibition of type IV fimbriae assembly|negative regulation of type IV fimbrial assembly|down regulation of type IV fimbrium assembly|down-regulation of type IV fimbrial assembly Any process that stops, prevents or reduces the frequency, rate or extent of type IV pilus biogenesis. GO:1903656 regulation of type IV pilus biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903656 regulation of type IV fimbrium assembly|regulation of type IV pilus biosynthesis|regulation of type IV fimbrium biogenesis|regulation of TFP biogenesis|regulation of type IV fimbria assembly|regulation of type IV fimbriae assembly|regulation of type IV fimbria biogenesis|regulation of type 4 pilus biogenesis|regulation of type IV fimbriae biogenesis|regulation of type IV fimbrial assembly|regulation of type IV fimbrial biogenesis Any process that modulates the frequency, rate or extent of type IV pilus biogenesis. GO:1903655 phosphorylation of RNA polymerase II C-terminal domain serine 2 residues involved in positive regulation of transcription elongation from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903655 Any phosphorylation of RNA polymerase II C-terminal domain serine 2 residues that is involved in positive regulation of transcription elongation from RNA polymerase II promoter. CHEBI:143597 pentanol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_143597 GO:1903654 phosphorylation of RNA polymerase II C-terminal domain serine 5 residues involved in positive regulation of transcription elongation from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903654 Any phosphorylation of RNA polymerase II C-terminal domain serine 5 residues that is involved in positive regulation of transcription elongation from RNA polymerase II promoter. GO:1903653 modulation by symbiont of host cell motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903653 modulation by symbiont of host cell movement|regulation by symbiont of host cell motility|modulation by symbiont of host cell locomotion Modulation of host cell motility by a symbiont of that host. GO:0048499 synaptic vesicle membrane organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048499 synaptic vesicle membrane organization and biogenesis|SLMV biogenesis|synaptic vesicle membrane organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the membrane surrounding a synaptic vesicle. GO:1903652 modulation by virus of host cytoplasmic transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903652 regulation by virus of host cytoplasmic transport|regulation by virus of host cytoplasmic streaming|viral modulation of host cytoplasmic trafficking Modulation by an infecting virus of host cytoplasmic transport. GO:0048498 establishment of petal orientation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048498 The process that determines the orientation of petals with reference to the central axis. GO:1903651 positive regulation of cytoplasmic transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903651 up regulation of cytoplasmic transport|up regulation of cytoplasmic streaming|activation of cytoplasmic transport|positive regulation of cytoplasmic streaming|activation of cytoplasmic streaming|up-regulation of cytoplasmic transport|up-regulation of cytoplasmic streaming|upregulation of cytoplasmic transport|upregulation of cytoplasmic streaming Any process that activates or increases the frequency, rate or extent of cytoplasmic transport. GO:1903661 positive regulation of complement-dependent cytotoxicity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903661 up-regulation of complement-dependent cytotoxicity|upregulation of complement-dependent cytotoxicity|up regulation of complement-dependent cytotoxicity|activation of complement-dependent cytotoxicity Any process that activates or increases the frequency, rate or extent of complement-dependent cytotoxicity. GO:1903660 negative regulation of complement-dependent cytotoxicity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903660 down regulation of complement-dependent cytotoxicity|downregulation of complement-dependent cytotoxicity|down-regulation of complement-dependent cytotoxicity|inhibition of complement-dependent cytotoxicity Any process that stops, prevents or reduces the frequency, rate or extent of complement-dependent cytotoxicity. GO:0097431 mitotic spindle pole biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097431 Either of the ends of a mitotic spindle, a spindle that forms as part of mitosis, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules. GO:0000486 cleavage between 5.8S rRNA and 2S rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000486 Endonucleolytic cleavage between the 5.8S rRNA and the 2S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. UBERON:0001902 epithelium of small intestine biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001902 epithelial tissue of small intestine|small intestine epithelial tissue|small intestine epithelium|mid intestine epithelium|small bowel epithelium|small intestinal epithelium|epithelium of small bowel|epithelial tissue of small bowel|small bowel epithelial tissue An epithelium that is part of a small intestine [Automatically generated definition]. GO:0000485 cleavage between 2S rRNA and LSU-rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000485 Endonucleolytic cleavage between the LSU-rRNA and the 2S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. GO:0097430 copper ion import across prospore membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097430 copper ion import across prospore membrane|copper ion import into ascospore-type prospore|copper ion transport into forespores The directed movement of copper ions from outside of a cell, across an ascospore-type prospore membrane and into the cytosol. UBERON:0001905 pineal body biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001905 frontal organ|pineal gland (Galen)|epiphysis cerebri|pineal|epiphysis|corpus pineale|Pi|glandula pinealis|pineal gland|pineal organ|conarium|stirnorgan A midline, cone like structure located in the dorso-caudal roof of the 3rd ventricle, attached by peduncles to the habenular and posterior commissures. The stalk contains nerve fibers, blood vessels, connective tissue and parenchymal cells (Paxinos, The Rat Central Nervous System, 2nd ed, pg 399). GO:0000484 cleavage between SSU-rRNA and 5.8S rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000484 Endonucleolytic cleavage between the SSU-rRNA and the 5.8S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. GO:0097433 dense body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097433 NIF_Subcellular:sao730872736 An electron dense body which may contain granules. UBERON:0001904 habenula biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001904 ganglion intercrurale|nuclei habenulares|habenular nuclei|pineal peduncle|nucleus habenularis|ganglion interpedunculare|Hb|habenulae|habenula complex|habenular complex A segment of the epithalamus that has as its parts the habenular nuclei and the habenular commissure[FMA,modified]. GO:0097432 hippocampal pyramidal neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097432 The process in which a relatively unspecialized cell acquires specialized features of a hippocampal pyramidal neuron, a pyramidal cell of the hippocampus. GO:0000483 endonucleolytic cleavage of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000483 Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with four genes, in this order, are produced in the nuclei of D. melanogaster as well as in those of other dipteran species. GO:0000489 maturation of SSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000489 Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. UBERON:0001901 epithelium of trachea biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001901 windpipe epithelium|epithelial tissue of trachea|trachea epithelial tissue|epithelial tissue of windpipe|epithelium of windpipe|trachea epithelium|tracheal epithelium|windpipe epithelial tissue the epithelial lining of the trachea which contains numerous ciliated cells GO:0000488 maturation of LSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000488 Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. UBERON:0001900 ventral thalamus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001900 thalamus ventralis|SbTh|perithalamus|subthalamic region|subthalamus|prethalamus|ventral thalamus Anterior part of the diencephalon that lies between the dorsal thalamus, hypothalamus, and tegmentum of the mesencephalon, including subthalamic nucleus, zona incerta, the fields of Forel, and the nucleus of ansa lenticularis[GO, modified]. GO:0000487 maturation of 5.8S rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000487 Any process involved in the maturation of a precursor 5.8S ribosomal RNA (rRNA) molecule into a mature 5.8S rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 8.8S rRNA, the 2S rRNA, and the Large Subunit (LSU) in that order from 5' to 3' along the primary transcript. GO:1903669 positive regulation of chemorepellent activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903669 up-regulation of chemorepellant activity|up-regulation of chemorepellent activity|upregulation of chemorepellant activity|upregulation of chemorepellent activity|up regulation of chemorepellant activity|activation of chemorepellant activity|positive regulation of chemorepellant activity|up regulation of chemorepellent activity|activation of chemorepellent activity Any process that activates or increases the frequency, rate or extent of chemorepellent activity. GO:1903668 negative regulation of chemorepellent activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903668 inhibition of chemorepellant activity|inhibition of chemorepellent activity|down regulation of chemorepellant activity|downregulation of chemorepellant activity|down regulation of chemorepellent activity|downregulation of chemorepellent activity|down-regulation of chemorepellant activity|negative regulation of chemorepellant activity|down-regulation of chemorepellent activity Any process that stops, prevents or reduces the frequency, rate or extent of chemorepellent activity. GO:1903667 regulation of chemorepellent activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903667 regulation of chemorepellant activity Any process that modulates the frequency, rate or extent of chemorepellent activity. GO:1903666 positive regulation of asexual reproduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903666 up regulation of asexual reproduction|upregulation of asexual reproduction|up-regulation of asexual reproduction|activation of asexual reproduction Any process that activates or increases the frequency, rate or extent of asexual reproduction. GO:0000482 maturation of 5S rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000482 Any process involved in the maturation of a precursor 5S ribosomal RNA (rRNA) molecule into a mature 5S rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. GO:1903665 negative regulation of asexual reproduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903665 downregulation of asexual reproduction|down regulation of asexual reproduction|inhibition of asexual reproduction|down-regulation of asexual reproduction Any process that stops, prevents or reduces the frequency, rate or extent of asexual reproduction. UBERON:0001906 subthalamic nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001906 Luy's body|corpus subthalamicum|nucleus of corpus luysii|subthalamic nucleus of Luys|nucleus of Luys|subthalamic nucleus (of Luys)|Luys' body|Luys' nucleus|nucleus subthalamicus|body of Luys|corpus Luysi|body of Forel The subthalamic nucleus is the lens-shaped nucleus located in the ventral part of the subthalamus on the inner aspect of the internal capsule that is concerned with the integration of somatic motor function[GO]. GO:1903664 regulation of asexual reproduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903664 Any process that modulates the frequency, rate or extent of asexual reproduction. GO:0000481 maturation of 5S rRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000481 Any process involved in the maturation of a precursor 5S ribosomal RNA (rRNA) molecule into a mature 5S rRNA molecule. UBERON:0001909 habenular commissure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001909 HBC|commissure habenularum|commissura habenularum|habenular commisure|commissura habenularis|habenular commissure (Haller) A brain commissure that is situated in front of the pineal gland and connects the habenular nucleus on one side of the diencephalon with that on the other side. GO:1903663 L-altrarate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903663 L-altrarate(1-) degradation|L-altrarate(1-) breakdown|L-altrarate(1-) catabolism The chemical reactions and pathways resulting in the breakdown of L-altrarate. GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000480 endonucleolytic cleavage at A0|endonucleolytic cleavage at A-prime Endonucleolytic cleavage within the 5'-External Transcribed Spacer (ETS) of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. Endonucleolytic cleavage within the 5'-ETS of the pre-RNA is conserved as one of the early steps of rRNA processing in all eukaryotes, but the specific position of cleavage is variable. UBERON:0001908 optic tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001908 tractus opticus|optic tracts|optic lemniscus|visual pathway|tractus optici Diencephalic white matter (tract) which is comprised of retinal ganglion cell axons after which they have passed through the optic chiasm[ZFA]. Predominantly white matter structure found in diencephalon consisting of fibers originating in the retina. The optic tract is considered to extend from the point of the optic chiasm and terminates largely, although not exclusively, in the lateral geniculate complex. Other fibers end in the superior colliculus and other structures in the diencephalon, midbrain and brainstem (MM)[NIF]. GO:1903662 L-altrarate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903662 L-altrarate(1-) metabolism The chemical reactions and pathways involving L-altrarate. GO:1903672 positive regulation of sprouting angiogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903672 up regulation of sprouting angiogenesis|upregulation of sprouting angiogenesis|up-regulation of sprouting angiogenesis|activation of sprouting angiogenesis Any process that activates or increases the frequency, rate or extent of sprouting angiogenesis. GO:1903671 negative regulation of sprouting angiogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903671 downregulation of sprouting angiogenesis|down regulation of sprouting angiogenesis|inhibition of sprouting angiogenesis|down-regulation of sprouting angiogenesis Any process that stops, prevents or reduces the frequency, rate or extent of sprouting angiogenesis. GO:1903670 regulation of sprouting angiogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903670 Any process that modulates the frequency, rate or extent of sprouting angiogenesis. GO:0097439 acquisition of desiccation tolerance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097439 The process in which tolerance to severe drying is acquired, before entering into a dry, either dormant or quiescent state. GO:0097438 exit from dormancy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097438 release from dormancy The dormancy process that results in exit from dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated. GO:0097435 supramolecular fiber organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097435 fibril organization|extracellular fibril organization and biogenesis|extracellular fibril organisation|fibril organisation|extracellular fibril organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a supramolecular fiber, a polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure. GO:0097434 succinate:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097434 succinate:hydrogen symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: succinate(out) + H+(out) = succinate(in) + H+(in). GO:0097437 maintenance of dormancy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097437 The dormancy process that results in an organism remaining in dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated. GO:0097436 entry into dormancy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097436 induction of dormancy The dormancy process that results in entry into dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated. GO:0097442 CA3 pyramidal cell dendrite biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097442 NIF_Subcellular:nlx_subcell_1005001 A dendrite of a hippocampal CA3 pyramidal cell. GO:0000497 DNA template activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000497 base pairing with DNA Interacting selectively and non-covalently with nucleic acid via hydrogen bonds between the bases of a gene product molecule and the bases of a target DNA molecule. GO:0097441 basal dendrite biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097441 NIF_Subcellular:sao1079900774 basilar dendrite A dendrite that emerges near the basal pole of a neuron. In bipolar neurons, basal dendrites are either on the same side of the soma as the axon, or project toward the axon. GO:0000496 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000496 GO:0097444 spine apparatus biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0097444 NIF_Subcellular:sao725931194 dense material A specialization of the endomembrane system found in some classes of dendritic spines consisting of two or more closely apposed lamellae with interspersed electron dense material. The endomembrane component is continuous with the smooth endoplasmic reticulum. GO:0000495 box H/ACA RNA 3'-end processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000495 box H/ACA RNA 3' end processing|box H/ACA sRNA 3'-end processing|box H/ACA snoRNA 3'-end processing Any process involved in forming the mature 3' end of a box H/ACA RNA molecule. GO:0097443 sorting endosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097443 NIF_Subcellular:sao1028571114 MVB-tubule complex A multivesicular body surrounded by and connected with multiple tubular compartments with associated vesicles. GO:0000494 box C/D RNA 3'-end processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000494 box C/D RNA 3' end processing|box C/D sRNA 3'-end processing|box C/D snoRNA 3'-end processing Any process involved in forming the mature 3' end of a box C/D RNA molecule. GO:0097440 apical dendrite biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097440 NIF_Subcellular:sao273773228 A dendrite that emerges near the apical pole of a neuron. In bipolar neurons, apical dendrites are located on the opposite side of the soma from the axon. GO:0000499 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000499 GO:0000498 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000498 GO:1903679 positive regulation of cap-independent translational initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903679 up regulation of cap-independent translational initiation|upregulation of cap-independent translational initiation|activation of cap-independent translational initiation|up-regulation of cap-independent translational initiation Any process that activates or increases the frequency, rate or extent of cap-independent translational initiation. GO:1903678 negative regulation of cap-independent translational initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903678 downregulation of cap-independent translational initiation|down regulation of cap-independent translational initiation|inhibition of cap-independent translational initiation|down-regulation of cap-independent translational initiation Any process that stops, prevents or reduces the frequency, rate or extent of cap-independent translational initiation. GO:1903677 regulation of cap-independent translational initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903677 Any process that modulates the frequency, rate or extent of cap-independent translational initiation. GO:1903676 positive regulation of cap-dependent translational initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903676 up regulation of cap-dependent translational initiation|upregulation of cap-dependent translational initiation|up-regulation of cap-dependent translational initiation|activation of cap-dependent translational initiation Any process that activates or increases the frequency, rate or extent of cap-dependent translational initiation. GO:0000493 box H/ACA snoRNP assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000493 box H/ACA small nucleolar ribonucleoprotein complex assembly The aggregation, arrangement and bonding together of proteins and a box H/ACA snoRNA to form a box H/ACA small nucleolar ribonucleoprotein (snoRNP) complex. GO:1903675 negative regulation of cap-dependent translational initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903675 down-regulation of cap-dependent translational initiation|downregulation of cap-dependent translational initiation|down regulation of cap-dependent translational initiation|inhibition of cap-dependent translational initiation Any process that stops, prevents or reduces the frequency, rate or extent of cap-dependent translational initiation. GO:0000492 box C/D snoRNP assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000492 box C/D small nucleolar ribonucleoprotein complex assembly The aggregation, arrangement and bonding together of proteins and a box C/D snoRNA to form a box C/D small nucleolar ribonucleoprotein (snoRNP) complex. GO:1903674 regulation of cap-dependent translational initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903674 Any process that modulates the frequency, rate or extent of cap-dependent translational initiation. GO:0000491 small nucleolar ribonucleoprotein complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000491 snoRNP assembly The aggregation, arrangement and bonding together of proteins and a snoRNA to form a small nucleolar ribonucleoprotein (snoRNP) complex. GO:1903673 mitotic cleavage furrow formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903673 cleavage furrow positioning involved in mitotic cell cycle Any cleavage furrow formation that is involved in mitotic cell cycle. GO:0000490 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000490 GO:1903683 positive regulation of epithelial cell-cell adhesion involved in epithelium migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903683 up regulation of epithelial cell-cell adhesion involved in epithelium migration|upregulation of epithelial cell-cell adhesion involved in epithelium migration|up-regulation of epithelial cell-cell adhesion involved in epithelium migration|activation of epithelial cell-cell adhesion involved in epithelium migration Any process that activates or increases the frequency, rate or extent of epithelial cell-cell adhesion involved in epithelium migration. GO:1903682 negative regulation of epithelial cell-cell adhesion involved in epithelium migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903682 downregulation of epithelial cell-cell adhesion involved in epithelium migration|down regulation of epithelial cell-cell adhesion involved in epithelium migration|inhibition of epithelial cell-cell adhesion involved in epithelium migration|down-regulation of epithelial cell-cell adhesion involved in epithelium migration Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell-cell adhesion involved in epithelium migration. GO:1903681 regulation of epithelial cell-cell adhesion involved in epithelium migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903681 Any process that modulates the frequency, rate or extent of epithelial cell-cell adhesion involved in epithelium migration. GO:1903680 acinar cell of sebaceous gland differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903680 sebocyte differentiation The process in which a relatively unspecialized cell acquires the specialized features of an acinar cell of sebaceous gland. GO:0097449 astrocyte projection biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097449 NIF_Subcellular:sao1630537580 peripheral astrocyte process|astrocyte process|vellous process A prolongation or process extending from the soma of an astrocyte and wrapping around neurons. GO:0097446 protein localization to eisosome filament biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097446 protein localization to linear eisosome A process in which a protein is transported to, and/or maintained in, a specific location in a eisosome filament (also called linear eisosome), a filamentous cortical structure formed, in S. pombe, by the eisosome component Pil1. GO:0097445 presynaptic active zone dense projection biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097445 NIF_Subcellular:sao494258938 active zone dense projection|pre-synaptic active zone dense projection Electron dense projection extending from the cytomatrix into the cytoplasm on which synaptic vesicles are tethered. GO:0097448 spine mat biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097448 NIF_Subcellular:sao2128156969 A configuration of neuron spines found on ciliary ganglion neurons in the embryonic and adult brain consisting of patches of closely spaced spines lying flat against the soma. GO:0097447 dendritic tree biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097447 NIF_Subcellular:sao172297168 The entire complement of dendrites for a neuron, consisting of each primary dendrite and all its branches. GO:0000464 endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000464 endonucleolytic cleavage at A3 Endonucleolytic cleavage within Internal Transcribed Spacer 1 (ITS1) upstream of the 5.8S rRNA derived from an originally tricistronic rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. In S. cerevisiae, this endonucleolytic cleavage within ITS1 initiates the maturation of the LSU and the 5.8S rRNAs. GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000463 Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript. GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000462 maturation of 18S rRNA Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and the Large Subunit (LSU) in that order from 5' to 3' along the primary transcript. GO:0097411 hypoxia-inducible factor-1alpha signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097411 HIF1alpha pathway|hypoxia-inducible factor-1alpha signalling pathway|hypoxia-inducible factor signaling A series of molecular signals mediated by hypoxia-inducible factor (HIF1) in response to lowered oxygen levels (hypoxia). Under hypoxic conditions, the oxygen-sensitive alpha-subunit of hypoxia-inducible factor (HIF)-1 dimerizes with a HIF1-beta subunit (also called ARNT or aryl-hydrocarbon-receptor nuclear translocator), translocates to the nucleus and activates transcription of genes whose products participate in responding to hypoxia. GO:0097410 hippocampal interneuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097410 The process in which a relatively unspecialized cell acquires specialized features of a hippocampal interneuron. GO:0000461 endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000461 endonucleolytic cleavage at site D Endonucleolytic cleavage at the 3'-end of the SSU-rRNA from an originally tricistronic rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript, to produce the mature end of the SSU-rRNA. GO:0000468 generation of mature 3'-end of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000468 processing at B2 Any process involved in generating the mature 3'-end of an LSU-rRNA derived from a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. GO:0000467 exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000467 Exonucleolytic digestion of a pre-rRNA molecule to generate the mature 3'-end of a 5.8S rRNA molecule derived from an originally tricistronic pre-rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000466 Any process involved in the maturation of an rRNA molecule originally produced as part of a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. GO:0000465 exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000465 Exonucleolytic digestion of a pre-rRNA molecule to generate the mature 5'-end of a 5.8S rRNA molecule derived from an originally tricistronic pre-rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. CHEBI:143566 3beta-hydroxy-4beta-hydroxymethyl-4alpha-methylsteroid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_143566 GO:1903689 regulation of wound healing, spreading of epidermal cells biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903689 Any process that modulates the frequency, rate or extent of wound healing, spreading of epidermal cells. GO:1903688 positive regulation of border follicle cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903688 activation of border follicle cell migration Any process that activates or increases the frequency, rate or extent of border follicle cell migration. GO:1903687 negative regulation of border follicle cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903687 inhibition of border follicle cell migration Any process that stops, prevents or reduces the frequency, rate or extent of border follicle cell migration. GO:0000460 maturation of 5.8S rRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000460 Any process involved in the maturation of a precursor 5.8S ribosomal RNA (rRNA) molecule into a mature 5.8S rRNA molecule. CHEBI:143563 3beta-hydroxy-4,4-dimethylsteroid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_143563 GO:1903684 regulation of border follicle cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903684 regulation of border cell migration Any process that modulates the frequency, rate or extent of border follicle cell migration. GO:1903694 positive regulation of mitotic G1 cell cycle arrest in response to nitrogen starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903694 up-regulation of G1 mitotic cell cycle arrest in response to nitrogen starvation|up regulation of mitotic G1 cell cycle arrest in response to nitrogen starvation|activation of mitotic G1 cell cycle arrest in response to nitrogen starvation|upregulation of G1 mitotic cell cycle arrest in response to nitrogen starvation|up-regulation of mitotic G1 cell cycle arrest in response to nitrogen starvation|up regulation of G1 mitotic cell cycle arrest in response to nitrogen starvation|activation of G1 mitotic cell cycle arrest in response to nitrogen starvation|positive regulation of G1 mitotic cell cycle arrest in response to nitrogen starvation|upregulation of mitotic G1 cell cycle arrest in response to nitrogen starvation Any process that activates or increases the frequency, rate or extent of mitotic G1 cell cycle arrest in response to nitrogen starvation. GO:1903693 regulation of mitotic G1 cell cycle arrest in response to nitrogen starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903693 regulation of G1 mitotic cell cycle arrest in response to nitrogen starvation Any process that modulates the frequency, rate or extent of mitotic G1 cell cycle arrest in response to nitrogen starvation. GO:1903692 methionine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903692 methionine import into cell|methionine import The directed movement of methionine from outside of a cell, across the plasma membrane and into the cytosol. GO:1903691 positive regulation of wound healing, spreading of epidermal cells biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903691 upregulation of wound healing, spreading of epidermal cells|up regulation of wound healing, spreading of epidermal cells|activation of wound healing, spreading of epidermal cells|up-regulation of wound healing, spreading of epidermal cells Any process that activates or increases the frequency, rate or extent of wound healing, spreading of epidermal cells. GO:1903690 negative regulation of wound healing, spreading of epidermal cells biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903690 down regulation of wound healing, spreading of epidermal cells|downregulation of wound healing, spreading of epidermal cells|down-regulation of wound healing, spreading of epidermal cells|inhibition of wound healing, spreading of epidermal cells Any process that stops, prevents or reduces the frequency, rate or extent of wound healing, spreading of epidermal cells. GO:0097417 nematosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097417 NIF_Subcellular:sao138430598 Cytoplasmic, ball-like inclusion resembling a nucleolus and consisting of a convoluted network of electron-opaque strands embedded in a less dense matrix. It measures approximately 0.9 microns and lacks a limiting membrane. Its strands (diameter = 400-600 A) appear to be made of an entanglement of tightly packed filaments and particles approximately 25-50 A thick. Cytochemical studies suggest the presence of nonhistone proteins and some RNA. Usually only one such structure is present in a cell, and it appears to occur in most ganglion cells. Although they can be seen anywhere in the cell body, nematosomes are typically located in the perinuclear cytoplasm, where they are often associated with smooth-surfaced and coated vesicles. GO:0097416 Lewy body-like hyaline inclusion biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097416 NIF_Subcellular:nlx_subcell_20090105 LBHI Cytoplasmic inclusion found in neurons. It consists of filaments and granular materials, exhibits a dense core with a rough peripheral halo and lacks a limiting membrane. The filaments of these inclusions are composed of approximately 15-25 nm granule-coated fibrils in association with normal 10-nm neurofilaments. GO:0097419 Pick body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097419 NIF_Subcellular:nlx_subcell_20090102 Cellular inclusion composed of numerous tau fibrils arranged in a disorderly array. Tau protein is a major component, though Pick bodies also contain ubiquitin, alpha-synuclein, and apolipoprotein E. GO:0000469 cleavage involved in rRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000469 cleavage during rRNA processing Any phosphodiester bond hydrolysis involved in the conversion of a primary ribosomal RNA (rRNA) transcript into a mature rRNA molecule. GO:0097418 neurofibrillary tangle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097418 NIF_Subcellular:nlx_subcell_20090202|NIF_Subcellular:nlx_subcell_20090201|NIF_Subcellular:sao2409833926 flame-shaped neurofibrillary tangle|star-shaped neurofibrillary tangle Intracellular mass of paired, helically wound protein filaments (also called PHF) lying in the cytoplasm of neuronal cell bodies and neuritic cell processes. Neurofibrillary tangles contain an abnormally phosphorylated form of a microtubule-associated protein, tau. The shape of these inclusions may resemble a flame or a star. GO:0097413 Lewy body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097413 NIF_Subcellular:sao4933778419 cytoplasmic inclusion Cytoplasmic, spherical inclusion commonly found in damaged neurons, and composed of abnormally phosphorylated, neurofilament proteins aggregated with ubiquitin and alpha-synuclein. GO:0097412 hyaline inclusion biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097412 NIF_Subcellular:nlx_subcell_20090104 pale body A glass-like, pale intracellular inclusion. SO:0000410 protein_binding_site biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000410 protein binding site|INSDC_feature:protein_bind A binding site that, in the molecule, interacts selectively and non-covalently with polypeptide molecules. GO:0097415 cortical Lewy body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097415 NIF_Subcellular:sao4040591221 Cytoplasmic inclusion similar to a classical Lewy body but lacking a halo of protein fibrils. GO:0097414 classical Lewy body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097414 NIF_Subcellular:sao4749542545 brainstem Lewy body Cytoplasmic inclusion, 5 to 15 micrometers in diameter, with a dense core surrounded by a halo of 10 to 20 nm wide radially oriented alpha-synuclein fibrils. GO:0097420 skein-like inclusion biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097420 NIF_Subcellular:nlx_subcell_20090103 Intracytoplasmic filamentous structure frequently encountered in preparations immunostained for ubiquitin. GO:0000475 maturation of 2S rRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000475 Any process involved in the maturation of a precursor 2S ribosomal RNA (rRNA) molecule into a mature 2S rRNA molecule. GO:0000474 maturation of SSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000474 Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8 S rRNA, 2S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript. GO:0000473 maturation of LSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000473 Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8 S rRNA, 2S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript. GO:0097422 tubular endosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097422 NIF_Subcellular:sao1570660411|NIF_Subcellular:sao694815499 coated tip A network of fine tubules in the vicinity of the Golgi complex and around the centriole. GO:0097421 liver regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097421 The regrowth of lost or destroyed liver. GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000472 endonucleolytic cleavage at A1 Endonucleolytic cleavage between the 5'-External Transcribed Spacer (5'-ETS) and the 5' end of the SSU-rRNA of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript, to produce the mature end of the SSU-rRNA. GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000479 Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with three genes, in this order, are produced in the nuclei of many eukaryotic species, including S. cerevisiae. GO:0000478 endonucleolytic cleavage involved in rRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000478 endonucleolytic cleavage during rRNA processing Any endonucleolytic cleavage involved in the conversion of a primary ribosomal RNA (rRNA) transcript into a mature rRNA molecule. Some endonucleolytic cleavages produce the mature end, while others are a step in the process of generating the mature end from the pre-rRNA. GO:0000477 generation of mature 5'-end of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000477 processing at C1 Cleavage within ITS2 to generate the mature 5'-end of an LSU-rRNA derived from a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. GO:0000476 maturation of 4.5S rRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000476 Any process involved in the maturation of a precursor 4.5S ribosomal RNA (rRNA) molecule into a mature 4.5S rRNA molecule. GO:1903699 tarsal gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903699 Meibomian gland development|tarsoconjunctival gland development|glandula tarsales development|gland of Meibom development The process whose specific outcome is the progression of a tarsal gland over time, from its formation to the mature structure. GO:1903698 positive regulation of microvillus assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903698 up-regulation of microvillus assembly|activation of microvillus assembly|upregulation of microvillus biogenesis|up-regulation of microvillus biogenesis|up regulation of microvillus assembly|activation of microvillus biogenesis|positive regulation of microvillus biogenesis|upregulation of microvillus assembly|up regulation of microvillus biogenesis Any process that activates or increases the frequency, rate or extent of microvillus assembly. GO:0000471 endonucleolytic cleavage in 3'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000471 Endonucleolytic cleavage within the 3'-External Transcribed Spacer (ETS) of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. In S. cerevisiae, endonucleolytic cleavage within the 3'-ETS of the pre-RNA, which may occur cotranscriptionally, is the first step in rRNA processing, and initiates a cascade of subsequent processing and modification events. GO:1903697 negative regulation of microvillus assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903697 down regulation of microvillus biogenesis|inhibition of microvillus biogenesis|down-regulation of microvillus assembly|downregulation of microvillus assembly|down-regulation of microvillus biogenesis|negative regulation of microvillus biogenesis|down regulation of microvillus assembly|inhibition of microvillus assembly|downregulation of microvillus biogenesis Any process that stops, prevents or reduces the frequency, rate or extent of microvillus assembly. GO:0000470 maturation of LSU-rRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000470 Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule. GO:1903696 protein localization to horsetail-astral microtubule array biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903696 protein localization in horsetail-astral microtubule array|protein localisation to horsetail-astral microtubule array|protein localisation in horsetail-astral microtubule array A process in which a protein is transported to, or maintained in, a location within a horsetail-astral microtubule array. GO:1903695 MAPK cascade involved in ascospore formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903695 MAPKKK cascade during sporulation involved in ascospore formation|MAPK signalling involved in ascospore biosynthesis|MAP kinase kinase kinase cascade involved in ascospore formation|MAP kinase cascade involved in ascospore formation|MAPKKK cascade during sporulation involved in ascospore biosynthesis|mitogen-activated protein kinase cascade involved in ascospore biosynthesis|ERK/MAPK cascade involved in ascospore formation|mitogen-activated protein kinase cascade involved in ascospore formation|MAP kinase cascade involved in ascospore biosynthesis|MAP kinase kinase kinase cascade involved in ascospore biosynthesis|MAPKKK cascade involved in ascospore biosynthesis|MAPK cascade involved in ascospore biosynthesis|MAPK signal transduction involved in ascospore biosynthesis|MAPK signalling involved in ascospore formation|MAPK signal transduction involved in ascospore formation|MAPK signaling involved in ascospore formation|MAPK signaling involved in ascospore biosynthesis|MAPKKK cascade involved in ascospore formation|ERK/MAPK cascade involved in ascospore biosynthesis Any MAPK cascade that is involved in ascospore formation. SO:0000409 binding_site biolink:SequenceFeature go-plus SOFA|biosapiens http://purl.obolibrary.org/obo/SO_0000409 http://en.wikipedia.org/wiki/Binding_site binding site|binding_or_interaction_site|INSDC_feature:misc_binding|site A biological_region of sequence that, in the molecule, interacts selectively and non-covalently with other molecules. A region on the surface of a molecule that may interact with another molecule. When applied to polypeptides: Amino acids involved in binding or interactions. It can also apply to an amino acid bond which is represented by the positions of the two flanking amino acids. GO:0097428 protein maturation by iron-sulfur cluster transfer biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097428 The transfer of an assembled iron-sulfur cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein. GO:0097427 microtubule bundle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097427 NIF_Subcellular:sao1872343973 microtubule fascicle An arrangement of closely apposed microtubules running parallel to each other. GO:0097429 amino acid ligation activity by nonribosomal peptide synthase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097429 Catalysis of the ligation of an amino acid to another amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate, carried out by a nonribosomal peptide synthase. GO:0097424 nucleolus-associated heterochromatin biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097424 NIF_Subcellular:sao1210952635 Dense particles of heterochromatin, consisting of a loosely twisted strand about 600 Angstrom thick, found associated with the nucleolus. GO:0097423 mitochondrion-associated adherens complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097423 NIF_Subcellular:sao1933817066 MAC|mitochondrial adhaerens complex An organelle arrangement comprised of the following elements: a mitochondrion positioned near the presynaptic membrane; an electron-dense mitochondrial plaque adjacent to the outer mitochondrial membrane that faces the presynaptic membrane; filament-like elements appearing to link the mitochondrial plaque to a cell-cell junction region (sometimes termed punctum adherens); tubular or vesicular-appearing membrane (also called vesicular chain) interposed among the filaments. Mitochondrion-associated adherens complexes were initially described in the dorsal horn of the spinal cord. They are found in calyces and other large terminals of the auditory brainstem, and in a variety of mammalian species including humans. GO:0097426 glial filament biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097426 NIF_Subcellular:sao1863852493 An intermediate filament composed of glial fibrillary acidic protein (GFAP) and found in astrocytes. GO:0097425 obsolete smooth endoplasmic reticulum part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0097425 NIF_Subcellular:sao184202831 SER subcomponent OBSOLETE. Any constituent part of the smooth endoplasmic reticulum (also called smooth ER, or SER). CHEBI:73136 EC 1.1.1.184 [carbonyl reductase (NADPH)] inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73136 CHEBI:87781 (3S)-3-hydroxyoleoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87781 CHEBI:38808 calcium channel modulator biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38808 CHEBI:38807 calcium channel agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38807 CHEBI:87783 (25R)-3beta-hydroxycholest-5-en-7-one-26-oic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87783 CHEBI:87785 beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87785 CHEBI:87787 alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNac-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87787 CHEBI:38809 ryanodine receptor modulator biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38809 CHEBI:87789 beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87789 CHEBI:87788 beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1->1')-Cer(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87788 CHEBI:73131 2,3-bis-O-phytanyl-sn-glycerol 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73131 CHEBI:73134 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73134 CHEBI:73148 (S)-4-hydroxy-2-oxopentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73148 UBERON:0035295 left ear biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035295 The organ of hearing located on the left side of the head[ncit,modified]. CHEBI:38818 N-methylcoclaurine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38818 CHEBI:87772 (4Z)-2-oxohept-4-enedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87772 CHEBI:87771 (2Z,4Z)-2-hydroxyhepta-2,4-dienedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87771 CHEBI:87774 16alpha-hydroxydehydroepiandrosterone 3-sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87774 CHEBI:87773 (S)-4-hydroxy-2-oxoheptanedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87773 PR:000011116 NEDD8 protein biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000011116 neddylin|NEDD-8|NEDD8|neural precursor cell expressed developmentally down-regulated protein 8|ubiquitin-like protein Nedd8 A protein that is a translation product of the human NEDD8 gene or a 1:1 ortholog thereof. CHEBI:73142 (S)-4-hydroxy-2-oxohexanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73142 CHEBI:73143 (S)-4-hydroxy-2-oxopentanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73143 CHEBI:73145 N-hexadecanoylsphingosine 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73145 GO:0048406 nerve growth factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048406 NGF binding|neurotrophin TRKA receptor activity|beta-nerve growth factor binding Interacting selectively and non-covalently with nerve growth factor (NGF). UBERON:0011298 submucosa of uterine tube biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011298 tela submucosa tubae uterinae|submucous layer of uterine tube|submucosa of fallopian tube|uterine submucosa The submucous layer of the wall of the uterine tube. GO:0048405 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048405 GO:0048404 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048404 GO:0048403 brain-derived neurotrophic factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048403 neurotrophin TRKB receptor activity|BDNF binding Interacting selectively and non-covalently with brain-derived neurotrophic factor. GO:0048402 intermediate mesoderm structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048402 intermediate mesoderm structural organisation The process that contributes to the act of creating the structural organization of the intermediate mesoderm. This process pertains to the physical shaping of a rudimentary structure. GO:0048401 negative regulation of intermediate mesodermal cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048401 inhibition of intermediate mesodermal cell fate specification|down regulation of intermediate mesodermal cell fate specification|downregulation of intermediate mesodermal cell fate specification|down-regulation of intermediate mesodermal cell fate specification Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate mesoderm cell fate specification. GO:0048400 positive regulation of intermediate mesodermal cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048400 up-regulation of intermediate mesodermal cell fate specification|upregulation of intermediate mesodermal cell fate specification|up regulation of intermediate mesodermal cell fate specification|activation of intermediate mesodermal cell fate specification|stimulation of intermediate mesodermal cell fate specification Any process that activates or increases the frequency, rate or extent of intermediate mesoderm cell fate specification. UBERON:0011299 white matter of telencephalon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011299 telencephalic tract/commissure|telencephalic tracts|telencephalic white matter|predominantly white regional part of telencephalon A partion of white matter that is part of a telencephalon. This can be further subdivided in some species, for example, into hemisphere white matter and the corpus callosum. GO:0048409 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048409 GO:0048408 epidermal growth factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048408 EGF binding Interacting selectively and non-covalently with epidermal growth factor. GO:0048407 platelet-derived growth factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048407 PDGF binding Interacting selectively and non-covalently with platelet-derived growth factor. CHEBI:73151 (S)-4-hydroxy-2-oxohexanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73151 CHEBI:73152 2,6-dimethyldeca-2,4,6,8-tetraenedial biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73152 CHEBI:73155 trienoic fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73155 CHEBI:87792 alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87792 GO:0048417 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048417 CHEBI:87791 alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87791 GO:0048416 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048416 GO:0048415 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048415 GO:0048414 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048414 GO:0048413 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048413 GO:0048412 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048412 GO:0048411 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048411 GO:0048410 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048410 GO:0048419 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048419 GO:0048418 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048418 GO:0048420 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048420 GO:0048428 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048428 GO:0048427 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048427 GO:0048426 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048426 GO:0048425 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048425 GO:0048424 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048424 GO:0048423 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048423 GO:0048422 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048422 GO:0048421 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048421 GO:0048429 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048429 GO:0048431 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048431 GO:0048430 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048430 GO:0048439 flower morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048439 The process in which the anatomical structures of the flower are generated and organized. GO:0048438 floral whorl development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048438 collective phyllome structure development The process whose specific outcome is the progression of a floral whorl over time, from its formation to the mature structure. A floral whorl is a circular arrangement of parts of a flower arising from a stem of a plant. GO:0048437 floral organ development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048437 The process whose specific outcome is the progression of the floral organ over time, from its formation to the mature structure. GO:0048436 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048436 GO:0048435 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048435 GO:0048434 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048434 GO:0048433 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048433 GO:0048432 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048432 CHEBI:73180 beta-L-arabinofuranosyl-(1->2)-beta-L-arabinofuranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73180 CHEBI:73182 plant activator biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73182 CHEBI:73181 EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73181 CHEBI:73184 2-amino-4-hydroxypteridine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73184 CHEBI:73183 1-(5-phospho-beta-D-ribosyl)-ATP(6-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73183 CHEBI:73186 2,4-dihydroxypteridine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73186 GO:0048442 sepal development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048442 The process whose specific outcome is the progression of the sepal over time, from its formation to the mature structure. GO:0048441 petal development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048441 The process whose specific outcome is the progression of the petal over time, from its formation to the mature structure. GO:1903609 negative regulation of inward rectifier potassium channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903609 negative regulation of Kir channel activity|down-regulation of Kir channel activity|down regulation of inward rectifier potassium channel activity|downregulation of Kir channel activity|downregulation of inward rectifier potassium channel activity|down regulation of Kir channel activity|inhibition of Kir channel activity|down-regulation of inward rectifier potassium channel activity|inhibition of inward rectifier potassium channel activity Any process that stops, prevents or reduces the frequency, rate or extent of inward rectifier potassium channel activity. GO:0048440 carpel development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048440 The process whose specific outcome is the progression of the carpel over time, from its formation to the mature structure. A carpel is an organ (generally believed to be a modified foliar unit) at the centre of a flower, bearing one or more ovules and having its margins fused together or with other carpels to enclose the ovule in an ovary, and consisting also of a stigma and usually a style. GO:1903608 protein localization to cytoplasmic stress granule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903608 protein localisation in cytoplasmic stress granule|protein localization in cytoplasmic stress granule|protein localization to stress granule|protein localisation to cytoplasmic stress granule A process in which a protein is transported to, or maintained in, a location within a cytoplasmic stress granule. GO:1903607 cytochrome c biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903607 cytochrome c anabolism|cytochrome c synthesis|cytochrome c formation|cytochrome c biosynthesis The chemical reactions and pathways resulting in the formation of cytochrome c. GO:1903606 cytochrome c metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903606 cytochrome c metabolism The chemical reactions and pathways involving cytochrome c. GO:1903605 cytochrome biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903605 cytochrome anabolism|cytochrome biosynthesis|cytochrome synthesis|cytochrome formation The chemical reactions and pathways resulting in the formation of a cytochrome. GO:1903604 cytochrome metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903604 cytochrome metabolism The chemical reactions and pathways involving a cytochrome. GO:1903603 thermospermine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903603 thermospermine synthesis|thermospermine formation|thermospermine biosynthesis|thermospermine anabolism The chemical reactions and pathways resulting in the formation of thermospermine. GO:0048449 floral organ formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048449 The process that gives rise to floral organs. This process pertains to the initial formation of a structure from unspecified parts. GO:1903602 thermospermine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903602 thermospermine catabolism|thermospermine degradation|thermospermine breakdown The chemical reactions and pathways resulting in the breakdown of thermospermine. UBERON:0035267 neck of gallbladder biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035267 gallbladder neck|cervix of gallbladder The narrowest portion of the gallbladder and distal to the cystic duct. GO:1903601 thermospermine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903601 thermospermine metabolism The chemical reactions and pathways involving thermospermine. GO:0048448 stamen morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048448 The process in which the anatomical structures of the stamen are generated and organized. GO:1903600 glutaminase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1903600 Sno1p-Snz1p A protein complex which is capable of glutaminase activity. GO:0048447 sepal morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048447 The process in which the anatomical structures of the sepal are generated and organized. GO:0048446 petal morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048446 The process in which the anatomical structures of the petal are generated and organized. GO:0048445 carpel morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048445 The process in which the anatomical structures of the carpel are generated and organized. GO:0048444 floral organ morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048444 The process in which the anatomical structures of the floral organ are generated and organized. GO:0048443 stamen development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048443 The process whose specific outcome is the progression of the stamen over time, from its formation to the mature structure. CHEBI:73191 abscisic acid receptor agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73191 CHEBI:73194 17alpha-(N-acetyl-alpha-D-glucosaminyl)estradiol 3-glucosiduronate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73194 GO:0048453 sepal formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048453 The process that gives rise to the sepal. This process pertains to the initial formation of a structure from unspecified parts. GO:0048452 petal structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048452 petal structural organisation The process that contributes to the act of creating the structural organization of the petal. This process pertains to the physical shaping of a rudimentary structure. GO:0048451 petal formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048451 The process that gives rise to the petal. This process pertains to the initial formation of a structure from unspecified parts. GO:1903619 negative regulation of transdifferentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903619 down-regulation of transdifferentiation|downregulation of transdifferentiation|down regulation of transdifferentiation|inhibition of transdifferentiation Any process that stops, prevents or reduces the frequency, rate or extent of transdifferentiation. GO:0048450 floral organ structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048450 floral organ structural organisation The process that contributes to the act of creating the structural organization of floral organs. This process pertains to the physical shaping of a rudimentary structure. GO:1903618 regulation of transdifferentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903618 Any process that modulates the frequency, rate or extent of transdifferentiation. GO:1903617 positive regulation of mitotic cytokinesis, site selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903617 Any process that activates or increases the frequency, rate or extent of mitotic cytokinesis, site selection. GO:1903616 MAPK cascade involved in axon regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903616 MAPK signalling involved in axon regeneration|MAPK signal transduction involved in axon regeneration|MAPK signaling involved in axon regeneration|MAPKKK cascade involved in axon regeneration|MAPKKK cascade during sporulation involved in axon regeneration|MAP kinase kinase kinase cascade involved in axon regeneration|MAP kinase cascade involved in axon regeneration|ERK/MAPK cascade involved in axon regeneration|mitogen-activated protein kinase cascade involved in axon regeneration Any MAPK cascade that is involved in axon regeneration. GO:1903615 positive regulation of protein tyrosine phosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903615 upregulation of tyrosine O-phosphate phosphatase activity|upregulation of phosphoprotein phosphatase (phosphotyrosine) activity|upregulation of protein phosphotyrosine phosphatase activity|upregulation of phosphotyrosine protein phosphatase activity|up-regulation of PTPase activity|upregulation of phosphotyrosine histone phosphatase activity|positive regulation of phosphotyrosylprotein phosphatase activity|up-regulation of protein-tyrosine-phosphate phosphohydrolase activity|activation of protein-tyrosine-phosphate phosphohydrolase activity|up-regulation of PPT-phosphatase activity|up regulation of phosphotyrosylprotein phosphatase activity|upregulation of [phosphotyrosine]protein phosphatase activity|activation of PPT-phosphatase activity|up-regulation of tyrosylprotein phosphatase activity|up regulation of protein-tyrosine-phosphatase activity|up regulation of protein tyrosine phosphatase activity|up-regulation of phosphotyrosine phosphatase activity|positive regulation of PTP-phosphatase activity|activation of phosphotyrosine phosphatase activity|activation of protein-tyrosine-phosphatase activity|positive regulation of protein-tyrosine-phosphatase activity|activation of protein tyrosine phosphatase activity|up regulation of PTP-phosphatase activity|up regulation of phosphoprotein phosphatase (phosphotyrosine) activity|up regulation of tyrosine O-phosphate phosphatase activity|up-regulation of phosphotyrosine protein phosphatase activity|up-regulation of protein phosphotyrosine phosphatase activity|activation of phosphoprotein phosphatase (phosphotyrosine) activity|up-regulation of phosphotyrosine histone phosphatase activity|activation of protein phosphotyrosine phosphatase activity|activation of tyrosine O-phosphate phosphatase activity|positive regulation of phosphoprotein phosphatase (phosphotyrosine) activity|upregulation of PTPase activity|activation of phosphotyrosine protein phosphatase activity|positive regulation of tyrosine O-phosphate phosphatase activity|activation of phosphotyrosine histone phosphatase activity|upregulation of phosphotyrosylprotein phosphatase activity|positive regulation of protein-tyrosine-phosphate phosphohydrolase activity|up regulation of [phosphotyrosine]protein phosphatase activity|upregulation of tyrosylprotein phosphatase activity|positive regulation of PPT-phosphatase activity|up regulation of protein-tyrosine-phosphate phosphohydrolase activity|activation of [phosphotyrosine]protein phosphatase activity|up regulation of PPT-phosphatase activity|positive regulation of [phosphotyrosine]protein phosphatase activity|positive regulation of phosphotyrosine phosphatase activity|up-regulation of protein-tyrosine-phosphatase activity|upregulation of PTP-phosphatase activity|up-regulation of protein tyrosine phosphatase activity|up regulation of phosphotyrosine phosphatase activity|positive regulation of protein phosphotyrosine phosphatase activity|positive regulation of phosphotyrosine protein phosphatase activity|up regulation of PTPase activity|up-regulation of tyrosine O-phosphate phosphatase activity|positive regulation of phosphotyrosine histone phosphatase activity|up-regulation of phosphoprotein phosphatase (phosphotyrosine) activity|up regulation of protein phosphotyrosine phosphatase activity|positive regulation of PTPase activity|activation of PTPase activity|up regulation of phosphotyrosine protein phosphatase activity|up-regulation of phosphotyrosylprotein phosphatase activity|up regulation of phosphotyrosine histone phosphatase activity|activation of phosphotyrosylprotein phosphatase activity|up regulation of tyrosylprotein phosphatase activity|upregulation of protein-tyrosine-phosphate phosphohydrolase activity|upregulation of PPT-phosphatase activity|positive regulation of tyrosylprotein phosphatase activity|activation of tyrosylprotein phosphatase activity|up-regulation of [phosphotyrosine]protein phosphatase activity|upregulation of protein-tyrosine-phosphatase activity|up-regulation of PTP-phosphatase activity|upregulation of protein tyrosine phosphatase activity|activation of PTP-phosphatase activity|upregulation of phosphotyrosine phosphatase activity Any process that activates or increases the frequency, rate or extent of protein tyrosine phosphatase activity. GO:1903614 negative regulation of protein tyrosine phosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903614 down regulation of protein tyrosine phosphatase activity|down-regulation of tyrosylprotein phosphatase activity|down regulation of phosphotyrosine histone phosphatase activity|negative regulation of tyrosylprotein phosphatase activity|down regulation of protein-tyrosine-phosphatase activity|inhibition of phosphotyrosine protein phosphatase activity|inhibition of protein phosphotyrosine phosphatase activity|inhibition of phosphotyrosine histone phosphatase activity|down regulation of tyrosine O-phosphate phosphatase activity|down regulation of phosphoprotein phosphatase (phosphotyrosine) activity|inhibition of PTPase activity|down-regulation of PTP-phosphatase activity|downregulation of protein tyrosine phosphatase activity|downregulation of protein-tyrosine-phosphatase activity|negative regulation of PTP-phosphatase activity|downregulation of tyrosine O-phosphate phosphatase activity|downregulation of phosphoprotein phosphatase (phosphotyrosine) activity|inhibition of tyrosylprotein phosphatase activity|downregulation of phosphotyrosylprotein phosphatase activity|down regulation of [phosphotyrosine]protein phosphatase activity|negative regulation of protein-tyrosine-phosphate phosphohydrolase activity|down-regulation of protein-tyrosine-phosphate phosphohydrolase activity|down regulation of phosphotyrosylprotein phosphatase activity|down-regulation of PPT-phosphatase activity|negative regulation of PPT-phosphatase activity|downregulation of PTP-phosphatase activity|downregulation of [phosphotyrosine]protein phosphatase activity|down-regulation of protein tyrosine phosphatase activity|negative regulation of protein-tyrosine-phosphatase activity|down-regulation of protein-tyrosine-phosphatase activity|inhibition of phosphotyrosylprotein phosphatase activity|down regulation of PTPase activity|negative regulation of phosphotyrosine phosphatase activity|down-regulation of phosphotyrosine phosphatase activity|down-regulation of phosphoprotein phosphatase (phosphotyrosine) activity|negative regulation of phosphoprotein phosphatase (phosphotyrosine) activity|down-regulation of tyrosine O-phosphate phosphatase activity|negative regulation of tyrosine O-phosphate phosphatase activity|down regulation of PTP-phosphatase activity|negative regulation of phosphotyrosine protein phosphatase activity|down-regulation of phosphotyrosine protein phosphatase activity|negative regulation of protein phosphotyrosine phosphatase activity|down-regulation of protein phosphotyrosine phosphatase activity|downregulation of PTPase activity|down-regulation of phosphotyrosine histone phosphatase activity|inhibition of PTP-phosphatase activity|negative regulation of phosphotyrosine histone phosphatase activity|down regulation of tyrosylprotein phosphatase activity|inhibition of protein-tyrosine-phosphatase activity|downregulation of protein-tyrosine-phosphate phosphohydrolase activity|inhibition of protein tyrosine phosphatase activity|downregulation of PPT-phosphatase activity|negative regulation of [phosphotyrosine]protein phosphatase activity|down-regulation of [phosphotyrosine]protein phosphatase activity|inhibition of phosphoprotein phosphatase (phosphotyrosine) activity|inhibition of tyrosine O-phosphate phosphatase activity|downregulation of tyrosylprotein phosphatase activity|downregulation of phosphotyrosine phosphatase activity|down regulation of protein-tyrosine-phosphate phosphohydrolase activity|down regulation of PPT-phosphatase activity|inhibition of protein-tyrosine-phosphate phosphohydrolase activity|downregulation of protein phosphotyrosine phosphatase activity|inhibition of PPT-phosphatase activity|downregulation of phosphotyrosine protein phosphatase activity|negative regulation of PTPase activity|downregulation of phosphotyrosine histone phosphatase activity|down regulation of phosphotyrosine phosphatase activity|down-regulation of PTPase activity|inhibition of [phosphotyrosine]protein phosphatase activity|inhibition of phosphotyrosine phosphatase activity|down regulation of protein phosphotyrosine phosphatase activity|negative regulation of phosphotyrosylprotein phosphatase activity|down regulation of phosphotyrosine protein phosphatase activity|down-regulation of phosphotyrosylprotein phosphatase activity Any process that stops, prevents or reduces the frequency, rate or extent of protein tyrosine phosphatase activity. GO:1903613 regulation of protein tyrosine phosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903613 regulation of protein-tyrosine-phosphatase activity|regulation of phosphoprotein phosphatase (phosphotyrosine) activity|regulation of tyrosine O-phosphate phosphatase activity|regulation of phosphotyrosylprotein phosphatase activity|regulation of [phosphotyrosine]protein phosphatase activity|regulation of PTP-phosphatase activity|regulation of PTPase activity|regulation of tyrosylprotein phosphatase activity|regulation of protein-tyrosine-phosphate phosphohydrolase activity|regulation of PPT-phosphatase activity|regulation of phosphotyrosine phosphatase activity|regulation of phosphotyrosine protein phosphatase activity|regulation of protein phosphotyrosine phosphatase activity|regulation of phosphotyrosine histone phosphatase activity Any process that modulates the frequency, rate or extent of protein tyrosine phosphatase activity. GO:0048459 floral whorl structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048459 floral whorl structural organisation The process that contributes to the act of creating the structural organization of the floral whorl. This process pertains to the physical shaping of a rudimentary structure. GO:1903612 positive regulation of calcium-dependent ATPase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903612 up regulation of calcium-dependent ATPase activity|activation of calcium-dependent ATPase activity|up-regulation of calcium-dependent ATPase activity|upregulation of calcium-dependent ATPase activity Any process that activates or increases the frequency, rate or extent of calcium-dependent ATPase activity. GO:1903611 negative regulation of calcium-dependent ATPase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903611 downregulation of calcium-dependent ATPase activity|down-regulation of calcium-dependent ATPase activity|inhibition of calcium-dependent ATPase activity|down regulation of calcium-dependent ATPase activity Any process that stops, prevents or reduces the frequency, rate or extent of calcium-dependent ATPase activity. GO:0048458 floral whorl formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048458 The process that gives rise to the floral whorl. This process pertains to the initial formation of a structure from unspecified parts. GO:1903610 regulation of calcium-dependent ATPase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903610 Any process that modulates the frequency, rate or extent of calcium-dependent ATPase activity. GO:0048457 floral whorl morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048457 The process in which the anatomical structures of the floral whorl are generated and organized. GO:0048456 stamen structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048456 stamen structural organisation The process that contributes to the act of creating the structural organization of the stamen. This process pertains to the physical shaping of a rudimentary structure. GO:0048455 stamen formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048455 The process that contributes to the act of giving rise to the stamen. This process pertains to the initial formation of a structure from unspecified parts. GO:0048454 sepal structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048454 sepal structural organisation The process that contributes to the act of creating the structural organization of the sepal. This process pertains to the physical shaping of a rudimentary structure. CHEBI:24129 furans biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24129 UBERON:0001549 dorsal metatarsal vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001549 venae metatarsales dorsales|metatarsal vein The dorsal metatarsal veins are veins which drain the metatarsus of the foot. [WP,unvetted]. CHEBI:24128 furanocoumarin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24128 CHEBI:24127 fungicide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24127 CHEBI:63730 7-methylguanosine 5'-diphosphate(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63730 CHEBI:24121 fucosyl oligoglycosylceramide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24121 CHEBI:87701 (2E,5Z)-tetradecadienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87701 CHEBI:38767 benzothiophenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38767 CHEBI:63734 ketone hydrate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63734 CHEBI:63733 aldehyde hydrate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63733 CHEBI:87700 (24E)-3alpha,7alpha-dihydroxy-5beta-cholest-24-en-26-oyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87700 CHEBI:63732 1,1-diol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63732 CHEBI:87702 (24R,25R)-3alpha,7alpha,24-trihydroxy-5beta-cholestan-26-oyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87702 CHEBI:63731 9beta-pimara-7,15-dien-19-oic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63731 CHEBI:87705 (3S,5Z)-3-hydroxytetradec-5-enoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87705 CHEBI:63738 diadenosyl tetraphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63738 UBERON:8300002 left forelimb biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_8300002 A forelimb that is on the left side of a pectoral complex. CHEBI:63737 diadenosyl pentaphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63737 UBERON:8300001 right forelimb biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_8300001 A forelimb that is on the right side of a pectoral complex. CHEBI:87704 3alpha,7alpha-dihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87704 CHEBI:87707 (5Z)-3-oxotetradecenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87707 UBERON:8300004 left hindlimb biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_8300004 A hindlimb that is on the left side of a pelvic complex. CHEBI:63736 diadenosyl hexaphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63736 CHEBI:63735 (2Z,4Z)-2-hydroxyhexa-2,4-dienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63735 UBERON:8300003 right hindlimb biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_8300003 A hindlimb that is on the right side of a pelvic complex. UBERON:0001554 skin of hip biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001554 zone of skin of regio coxae|hip skin|hip region zone of skin|regio coxae zone of skin|hip zone of skin|zone of skin of hip region|zone of skin of hip A zone of skin that is part of a hip region. UBERON:0001556 lower urinary tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001556 Subdivision of urinary system which consists of the urinary bladder and the urethra. UBERON:0001555 digestive tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001555 digestive tube|alimentary canal|digestive canal|alimentary tract|enteric tract|gut|gut tube A tube extending from the mouth to the anus. CHEBI:63739 diadenosyl triphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63739 PR:000001946 tumor necrosis factor ligand superfamily member 10/11 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001946 A protein with core architecture consisting of a fairly small cytoplasmic region, a transmembrane domain, and an extracellular domain containing a TNF(Tumour Necrosis Factor) family domain (Pfam:PF00229). CHEBI:38763 chromanone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38763 UBERON:0025525 motor system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0025525 motor system The part of the central nervous system that is involved with movement. CHEBI:38762 isochromanes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38762 CHEBI:38761 isochromenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38761 CHEBI:38760 mellein biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38760 UBERON:0001536 left common carotid artery plus branches biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001536 left common carotid artery|left common carotid artery|trunk of left common carotid tree The leftmost of the two common carotid arteries, originating from the aortic arch in the thorax. CHEBI:24138 galactaric acid derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24138 CHEBI:63741 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63741 CHEBI:63740 P(1),P(6)-bis(5'-adenosyl)hexaphosphate(6-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63740 CHEBI:38778 triazinanes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38778 CHEBI:38777 azetidines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38777 CHEBI:63743 dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactopyranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63743 CHEBI:63742 (1E,2Z)-3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63742 CHEBI:38775 monohydroxyquinoline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38775 CHEBI:63749 (+)-artemisinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63749 PR:000001951 tumor necrosis factor receptor superfamily member 10A/B biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001951 A death receptor with core architecture consisting of a signal sequence, an extracellular region containing three TNFR/NGFR cysteine-rich region domains (Pfam:PF00020), a transmembrane region, and an intracellular region containing a Death domain (Pfam:PF00531). There are two genes in human, TNFRSF10A and TNFRSF10B, more closely related to each other than to mouse TNFRSF10B. CHEBI:63746 TRIBOA biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63746 CHEBI:38779 1,3,5-triazinanes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38779 UBERON:0001543 popliteal lymph node biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001543 popliteal lymph node|popliteal lymph glands|popliteal glands the lymph nodes which drain the legs; contained in the popliteal fossa CHEBI:38774 hydroxyquinoline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38774 CHEBI:38773 quinolinemonocarboxylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38773 UBERON:0025533 proprioceptive system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0025533 proprioceptive system The sensory system for the sense of proprioception. UBERON:0001529 brachiocephalic artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001529 innominate artery|truncus brachiocephalicus|truncus brachiocephalicus|innominate|brachiocephalic trunk the short first aortic arch branch and divides into the right subclavian artery and the right common carotid artery CHEBI:24103 fructosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24103 CHEBI:24108 fructosylglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24108 CHEBI:63750 (5S,9S,10S,13E)-labda-7,13-dien-15-yl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63750 CHEBI:38745 pentahydroxyflavanone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38745 CHEBI:38744 hexahydroxyflavanone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38744 CHEBI:38742 tetrahydroxyflavanone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38742 CHEBI:38749 dihydroxyflavanone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38749 CHEBI:38748 monohydroxyflavanone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38748 CHEBI:38747 taxifolin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38747 CHEBI:87728 isolithocholate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87728 UBERON:0001532 internal carotid artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001532 arteria carotis interna|internal carotid|ICA|cranial carotid artery A terminal branch of the left or right common carotid artery which supplies oxygenated blood to the brain and eyes[MP] UBERON:0001531 right common carotid artery plus branches biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001531 right common carotid artery|right common carotid artery|trunk of right common carotid tree The rightmost of the two common carotid arteries, originating from in the neck from the brachiocephalic trunk. UBERON:0001534 right subclavian artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001534 arteria subclavia dextra The subclavian artery that supplies the right pectoral appendage UBERON:0001533 subclavian artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001533 pectoral artery|arterial tree of upper limb|subclavian arterial tree|PA|arteria subclavia|arteria subclavia One of two laterally paired arteries that supplies the pectoral appendages, usually branching from the dorsal aorta CHEBI:24109 fructosyllysine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24109 CHEBI:38741 isoflavanones biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38741 CHEBI:38740 isoflavan biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38740 UBERON:0001530 common carotid artery plus branches biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001530 carotid artery|common carotid artery|trunk of common carotid tree|carotid artery system|a. carotis communis A bilaterally paired branched artery that originates from the aortic arches and divides into and includes as parts the internal and external carotid arteries[cjm]. PR:000001926 semaphorin biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001926 A protein with core architecture consisting of a signal sequence,a Sema domain (Pfam:PF01403), a Plexin repeat (Pfam:PF01437), and an Ig-like domain (Pfam:PF00047, Pfam:PF07686, or Pfam:PF07679). UBERON:0001518 skin of wrist biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001518 zone of skin of wrist|zone of skin of carpal region|wrist skin|carpal region zone of skin|wrist zone of skin A zone of skin that is part of a wrist [Automatically generated definition]. NCBITaxon:2864 Dinophyceae organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_2864 Chromophyta|Dinophyta|Pyrrophyta|Dinophycidae|algae|Pyrrhophyta|Dinoflagellata|dinoflagellates|dinoflagellates|dinophytes CHEBI:24115 fuconate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24115 UBERON:0001517 skin of elbow biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001517 elbow skin|elbow zone of skin|zone of skin of cubital region|zone of skin of elbow|cubital region zone of skin A zone of skin that is part of a elbow [Automatically generated definition]. CHEBI:24113 fructuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24113 UBERON:0001519 skin of manus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001519 skin of hand|hand skin|manus skin|skin of fore-paw A zone of skin that is part of a manus [Automatically generated definition]. CHEBI:24112 fructuronate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24112 CHEBI:24119 fucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24119 UBERON:0001514 descending aorta biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001514 aorta descendens|pars descendens aortae|pars descendens aortae The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries[GO]. The descending aorta is part of the aorta, the largest artery in the body. The descending aorta is the part of the aorta beginning at the aortic arch that runs down through the chest and abdomen. The descending aorta is divided into two portions, the thoracic and abdominal, in correspondence with the two great cavities of the trunk in which it is situated. Within the abdomen, the descending aorta branches into the two common iliac arteries which serve the legs. [WP,unvetted]. UBERON:0001513 skin of pes biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001513 skin of foot|foot skin|skin of hind-paw A zone of skin that is part of a pes [Automatically generated definition]. UBERON:0001516 abdominal aorta biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001516 descending abdominal aorta|pars abdominalis aortae|aorta abdominalis|abdominal part of aorta|pars abdominalis aortae|abdominal part of aorta Abdominal part of aorta: the distal part of the descending aorta, which is the continuation of the thoracic part and gives rise to the inferior phrenic, lumbar, median sacral, superior and inferior mesenteric, middle suprarenal, renal, and testicular or ovarian arteries, and celiac trunk[BTO]. The abdominal aorta is the largest artery in the abdominal cavity. As part of the aorta, it is a direct continuation of descending aorta(of the thorax). [WP,unvetted]. UBERON:0001515 thoracic aorta biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001515 aorta thoracalis|pars thoracica aortae|thoracic part of aorta|aorta thoracica the part of the aorta that extends from the origin at the heart to the diaphragm, and from which arises numerous branches that supply oxygenated blood to the chest cage and the organs within the chest CHEBI:24116 fuconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24116 CHEBI:87710 (3E)-tetradecenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87710 CHEBI:38756 methoxyisoflavone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38756 CL:1001434 olfactory bulb interneuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001434 A neuron residing in the olfactory bulb that serve to process and refine signals arising from olfactory sensory neurons CHEBI:87712 (2E,4E)-tetradecadienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87712 CL:1001433 epithelial cell of exocrine pancreas biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001433 exocrine pancreas cell An epithelial cell of the exocrine pancreas. CHEBI:38755 hydroxyisoflavone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38755 CHEBI:38759 isocoumarin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38759 CHEBI:38758 isocoumarins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38758 CHEBI:87718 (3S,7Z)-3-hydroxyhexadecenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87718 CHEBI:87717 (2E,7Z)-hexadecadienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87717 CHEBI:38757 isoflavones biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38757 CHEBI:87719 (7Z)-3-oxohexadecenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87719 CHEBI:38751 triamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38751 NCBITaxon:131567 cellular organisms organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_131567 biota CHEBI:63778 CMP-pseudaminic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63778 CHEBI:87747 7alpha-hydroxy-3-oxochol-4-en-24-oate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87747 UBERON:0001592 bronchial vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001592 bronchial venous tree The bronchial veins are small vessels that return blood from the larger bronchi and structures at the roots of the lungs. The right side drains into the azygos vein, while the left side drains into the left superior intercostal vein or the accessory hemiazygos vein. The bronchial veins are counterparts to the bronchial arteries. The veins, however, do not return all of the blood supplied by the arteries; much of the blood that is carried in the bronchial arteries is returned to the heart via the pulmonary veins. [WP,unvetted]. UBERON:0001591 thymic vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001591 vena thymica|venae thymicae|thymic tributary of brachiocephalic vein A vein that drains blood from the thymus. CHEBI:63775 1,2-dioleoyl-3-beta-D-galactosyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63775 CHEBI:87748 3-oxochola-4,6-dien-24-oate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87748 CHEBI:63779 alpha-D-Gal-(1->2)-alpha-D-Glc-(1->3')-1,2-diacylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63779 CHEBI:14750 acetylacetone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_14750 UBERON:0001593 venous plexus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001593 plexus venosus|venous network|rete venosum A congregation of multiple veins. UBERON:0001579 olfactory nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001579 first cranial nerve|1n|olfactoria fila|nervus olfactorius|nerve I|fila olfactoria|cranial nerve I|olfactory fila|olfactory nerve [I]|CN-I|nervus olfactorius [i]|olfactory i nerve|olfactory I|nerve of smell Nerve that carries information from the olfactory epithelium to the olfactory bulb[Butler and Hodos]. CHEBI:38739 trihydroxyflavanone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38739 CHEBI:87730 3beta,7alpha-dihydroxy-5beta-cholan-24-oate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87730 CHEBI:87731 7alpha-hydroxy-3-oxo-5beta-cholan-24-oate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87731 CHEBI:87734 12alpha-hydroxy-3-oxo-5beta-cholan-24-oate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87734 CHEBI:63788 alpha-D-Glc-(1->2)-alpha-D-Glc-(1->3')-1,2-diacylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63788 CHEBI:87733 3beta,12alpha-dihydroxy-5beta-cholan-24-oate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87733 CHEBI:87736 7alpha,12alpha-dihydroxy-3-oxo-5beta-cholan-24-oate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87736 PR:000001991 C-C motif chemokine 19 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001991 macrophage inflammatory protein 3 beta|beta chemokine exodus-3|CK beta-11|MIP-3-beta|EBI1 ligand chemokine|MIP3B|ELC|SCYA19|epstein-Barr virus-induced molecule 1 ligand chemokine|small-inducible cytokine A19|CCL19 A C/C-C motif small inducible chemokine that is a translation product of the human CCL19 gene or a 1:1 ortholog thereof. CHEBI:63786 beta-D-Glc-(1->6)-beta-D-Glc-(1->3')-1,2-diacylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63786 CHEBI:87735 3beta,7alpha,12alpha-trihydroxy-5beta-cholan-24-oate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87735 PR:000001993 C-C motif chemokine 21 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001993 CCL21|small-inducible cytokine A21c|secondary lymphoid-tissue chemokine|SLC|small-inducible cytokine A21b|small-inducible cytokine A21a|Scya21c|Scya21b|beta chemokine exodus-2|thymus-derived chemotactic agent 4|6Ckine|TCA4|Ccl21c|SCYA21|Ccl21b|small-inducible cytokine A21 A C/C-C motif small inducible chemokine that is a translation product of the human CCL21 gene or a 1:1 ortholog thereof. CHEBI:38738 monomethoxyflavanone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38738 UBERON:0001586 internal jugular vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001586 vena jugularis interna|internal jugular venous tree|internal jugular One of two jugular veins that collect the blood from the brain, the superficial parts of the face, and the neck. [WP,unvetted]. UBERON:0001585 anterior vena cava biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001585 cranial vena cava|superior vena cava|vena maxima|precava|vena cava superior|superior caval vein A vein that carries deoxygenated blood from the upper half of the body into the right atrium of the heart. UBERON:0001584 left subclavian artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001584 arteria subclavia (sinistra) The subclavian artery that supplies the left pectoral appendage CHEBI:73117 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-icosatetraenoyl)-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73117 UBERON:0001568 muscle of larynx biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001568 musculi laryngeales|larynx muscle organ|laryngeal muscle|muscle organ of larynx|larynx muscle The muscles associated with the larynx. GO:0048604 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048604 GO:0048603 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048603 GO:0048602 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048602 CHEBI:63790 glyco-amino-acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63790 GO:0048601 oocyte morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048601 oocyte morphogenesis during differentiation The process in which the structures of an oocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of an oocyte. CHEBI:38706 pediculicide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38706 CHEBI:63796 N(alpha)-citryl-N(epsilon)-acetyl-N(epsilon)-hydroxylysine(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63796 GO:0048600 oocyte fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048600 The process in which the developmental fate of a cell becomes restricted such that it will develop into an oocyte. CHEBI:63795 all-trans-4-hydroxyretinoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63795 CHEBI:63794 retinoid X receptor agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63794 CHEBI:87765 L-ribonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87765 CHEBI:87764 N-docosanoylglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87764 CHEBI:38700 organic sodium salt biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38700 CHEBI:87769 lithocholyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87769 GO:0048609 multicellular organismal reproductive process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048609 reproductive process in a multicellular organism|organismal reproductive process The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs. CHEBI:87768 N-hexacosanoylglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87768 GO:0048608 reproductive structure development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048608 The reproductive developmental process whose specific outcome is the progression of structures that will be used in the process of creating new individuals from one or more parents, from their formation to the mature structures. GO:0048607 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048607 GO:0048606 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048606 CHEBI:38702 inorganic sodium salt biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38702 GO:0048605 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048605 UBERON:0001576 intrinsic muscle of tongue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001576 intrinsic lingual muscle|intrinsic tongue muscle The intrinsic tongue muscles are an integral part of the tongue and completely contained within the tongue that are innervated by Cranial Nerve XII. UBERON:0001575 extrinsic muscle of tongue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001575 extrinsic lingual muscle|extrinsic tongue muscle A muscle organ that attaches the tongue to some other structure. UBERON:0001577 facial muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001577 facial muscle proper|cranial-facial muscle|muscle organ of face|musculi faciei|face muscle organ|facial muscle|muscle of facil expression|craniofacial muscle|muscles of facial expression|facial nerve muscle|muscle of face|mimetic muscles|facial nerve innervated muscle|cranio-facial muscle|face muscle A muscle innervated by a facial nerve. UBERON:0001572 hyoglossus muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001572 hyoglossus|m. hyoglossus A muscle that attaches to the hyopid bone and to the tongue and is innervated by cranial nerve XII UBERON:0001571 genioglossus muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001571 musculus genioglossus|genioglossus|m. genioglossus Either of a pair of lingual muscles with origin in the mandible, with insertion to the lingual fascia below the mucous membrane and epiglottis, with nerve supply from the hypoglossal nerve, and whose action depresses and protrudes the tongue. CHEBI:73110 ganglioside GM1(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73110 CHEBI:73126 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73126 CHEBI:73125 2,3-bis-O-phytanyl-sn-glycerol 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73125 CHEBI:73127 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73127 UBERON:0001558 lower respiratory tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001558 lower respiratory system The segment of the respiratory tract that starts proximally with the trachea and includes all distal structures including the lungs[WP,modified] UBERON:0001557 upper respiratory tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001557 The segment of the respiratory tract that starts proximally with the nose and ends distally with the cricoid cartilage, before continuing to the trachea. GO:0048615 embryonic anterior midgut (ectodermal) morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048615 The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and organized, during the embryonic phase. GO:0048614 post-embryonic ectodermal digestive tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048614 post-embryonic ectodermal gut morphogenesis The process, occurring during the post-embryonic phase, by which the anatomical structures of the ectodermal gut are generated and organized. GO:0048613 embryonic ectodermal digestive tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048613 embryonic ectodermal gut morphogenesis The process, occurring during the embryonic phase, by which the anatomical structures of the ectodermal digestive tract are generated and organized. GO:0048612 post-embryonic ectodermal digestive tract development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048612 post-embryonic ectodermal gut development The process, occurring during the post-embryonic phase, whose specific outcome is the progression of the ectodermal gut over time, from its formation to the mature structure. CHEBI:38717 carboxylic acid trianion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38717 GO:0048611 embryonic ectodermal digestive tract development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048611 embryonic ectodermal gut development The process, occurring during the embryonic phase, whose specific outcome is the progression of the ectodermal gut over time, from its formation to the mature structure. CHEBI:87751 ocimene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87751 GO:0048610 obsolete cellular process involved in reproduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048610 reproductive cellular process|cellular process involved in reproduction OBSOLETE. A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular or single-celled organism. CHEBI:87753 D-gulonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87753 GO:0048619 embryonic hindgut morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048619 The process in which the anatomical structures of the hindgut are generated and organized, during the embryonic phase. CHEBI:38716 carboxylic acid dianion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38716 PR:000001971 vascular endothelial growth factor receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001971 A protein with core architecture consisting of a signal sequence, followed by 7 Ig-like domains (Pfam:PF00047, Pfam:PF07679, or Pfam:PF07686), a transmembrane region, and a cytoplasmic Protein tyrosine kinase domain. GO:0048618 post-embryonic foregut morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048618 The process in which the anatomical structures of the foregut are generated and organized, during the post-embryonic phase. GO:0048617 embryonic foregut morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048617 The process in which the anatomical structures of the foregut are generated and organized, during the embryonic phase. GO:0048616 post-embryonic anterior midgut (ectodermal) morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048616 The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and organized, during the post-embryonic phase. UBERON:0001560 neck of organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001560 organ neck CHEBI:73121 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73121 CHEBI:73124 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73124 GO:0097596 ventral disc supernumerary microtubule array biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097596 supernumerary microtubule array|ventral disk supernumerary microtubule array A partial left-handed spiral array of microtubules that lies generally dorsal to the main ventral disc microtubule array in Giardia species (trophozoite stage). GO:0097595 ventral disc crossbridge biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097595 crossbridge|ventral disk crossbridge Structure horizontally linking adjacent microribbons of the ventral disc in Giardia species (trophozoite stage). The composition of crossbridges is not fully known yet. GO:0097598 sperm cytoplasmic droplet biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097598 sperm residual cytoplasm A small amount of cytoplasm surrounded by a cell membrane that is generally retained in spermatozoa after spermiogenesis, when the majority of the cytoplasm is phagocytosed by Sertoli cells to produce what are called residual bodies. Initially, the droplet is located at the neck just behind the head of an elongated spermatid. During epididymal transit, the cytoplasmic droplet migrates caudally to the annulus at the end of the midpiece; the exact position and time varies by species. The cytoplasmic droplet consists of lipids, lipoproteins, RNAs, a variety of hydrolytic enzymes, receptors, ion channels, and Golgi-derived vesicles. The droplet may be involved in regulatory volume loss (RVD) at ejaculation, and in most species, though not in humans, the cytoplasmic droplet is lost at ejaculation. Note that the cytoplasmic droplet is distinct from 'excessive residual cytoplasm' that sometimes remains in epididymal spermatozoa, particularly when spermiogenesis has been disrupted. GO:0097597 ventral disc biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097597 ventral adhesive disc|ventral disk|adhesive disc Specialized organelle found in Giardia species (trophozoite stage) and characterized by a spiral array of microtubules and microtubule-associated structures including dorsal microribbons and crossbridges. The edge of the ventral disc narrows into a lateral crest. The ventral disk mediates mechanical attachment of the trophozoite to the host's intestinal wall, and contains the contractile proteins actinin, alpha-actinin, myosin, and tropomyosin working towards contraction of the disk involved in adherence. GO:0097592 ventral disc overlap zone biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097592 overlap zone|ventral disk overlap zone A region of the ventral disc of Giardia species (trophozoite stage) where two portions of the same array of microtubules overlap (the microtubule array makes a complete circle and overlaps on itself). GO:0097591 ventral disc lateral crest biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097591 lateral crest|ventral disk lateral crest Fibrillar repetitive structure surrounding the ventral disc edge in Giardia species (trophozoite stage). The composition of the lateral crest is not fully known yet. GO:0097594 ventral disc dorsal microribbon biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097594 ventral disk dorsal microribbon|dorsal ribbon|microribbon|dorsal microribbon Trilaminar structure extending perpendicularly into the cytoplasm along the length of ventral disc microtubules in Giardia species (trophozoite stage). Constituents of dorsal microribbons (also called dorsal ribbons or microribbons) include alpha-coiled-helix proteins approximately 29 to 38 kDa in size. These proteins line the edges of the microribbons but are not found in microtubules. Tubulins are not found in microribbons. GO:0009019 tRNA (guanine-N1-)-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009019 Reactome:R-HSA-6787591|Reactome:R-HSA-6786621|Reactome:R-HSA-6782859 S-adenosyl-L-methionine:tRNA (guanine-N1-)-methyltransferase activity|tRNA guanine 1-methyltransferase activity|S-adenosyl-L-methionine:tRNA (guanine-1-N-)-methyltransferase activity|transfer ribonucleate guanine 1-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N1-methylguanine. GO:0097593 ventral disc microtubule array biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097593 ventral disk microtubule array|spiral microtubule array|ventral disc spiral microtubule array A part of the ventral disc of Giardia species (trophozoite stage) consisting of a spiral array of microtubules linked to the ventral membrane. These microtubules form the base of the ventral disc dorsal microribbons that extend nearly perpendicular from the membrane. GO:0010007 magnesium chelatase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0010007 A heterotrimeric enzyme complex composed of three subunits, all of which are required for enzyme activity, which catalyzes the chelation of Mg by proto IX in an ATP-dependent manner. GO:0009018 sucrose phosphorylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009018 RHEA:24048|EC:2.4.1.7|MetaCyc:SUCROSE-PHOSPHORYLASE-RXN disaccharide glucosyltransferase activity|sucrose glucosyltransferase activity|sucrose:phosphate alpha-D-glucosyltransferase activity Catalysis of the reaction: sucrose + phosphate = D-fructose + alpha-D-glucose 1-phosphate. GO:0009017 succinylglutamate desuccinylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009017 KEGG_REACTION:R00411|EC:3.5.1.96|RHEA:15169|MetaCyc:SUCCGLUDESUCC-RXN AstE|SGDS|N2-succinylglutamate desuccinylase activity|N-succinyl-L-glutamate amidohydrolase activity Catalysis of the reaction: N-succinyl-L-glutamate + H(2)O = L-glutamate + succinate. GO:0010006 Toc complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0010006 Protein translocon complex at the chloroplast outer membrane. GO:0009016 succinyldiaminopimelate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009016 RHEA:11960|KEGG_REACTION:R04475|MetaCyc:SUCCINYLDIAMINOPIMTRANS-RXN|EC:2.6.1.17 succinyldiaminopimelate transferase activity|N-succinyl-L-diaminopimelic glutamic transaminase activity|N-succinyl-L-2,6-diaminoheptanedioate:2-oxoglutarate aminotransferase activity|succinyldiaminopimelate aminotransferase activity Catalysis of the reaction: 2-oxoglutarate + N-succinyl-LL-2,6-diaminopimelate = L-2-succinylamino-6-oxopimelate + L-glutamate. GO:0010009 cytoplasmic side of endosome membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0010009 external side of endosome membrane|external leaflet of endosome membrane The side (leaflet) of the endosome membrane that faces the cytoplasm. GO:0097590 archaeal-type flagellum-dependent cell motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097590 archaeal-type flagellar cell motility Cell motility due to the motion of one or more archaeal-type flagella. An archaeal-type flagellum (also called archaellum) is a non-membrane-bounded organelle superficially similar to a bacterial-type flagellum, but having a different molecular structure and lacking a central channel. GO:0009015 N-succinylarginine dihydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009015 EC:3.5.3.23|KEGG_REACTION:R04189|RHEA:19533|MetaCyc:SUCCARGDIHYDRO-RXN N2-succinyl-L-arginine iminohydrolase (decarboxylating)|SADH|arginine succinylhydrolase activity|2-N-succinyl-L-arginine iminohydrolase (decarboxylating)|succinylarginine dihydrolase activity|AstB|AruB|N2-succinylarginine dihydrolase activity Catalysis of the reaction: N(2)-succinyl-L-arginine + 2 H(2)O + 2 H(+) = N(2)-succinyl-L-ornithine + CO(2) + 2 NH(4)(+). GO:0010008 endosome membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0010008 NIF_Subcellular:sao978443756 endosomal membrane The lipid bilayer surrounding an endosome. GO:0009014 succinyl-diaminopimelate desuccinylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009014 RHEA:22608|EC:3.5.1.18|KEGG_REACTION:R02734|MetaCyc:SUCCDIAMINOPIMDESUCC-RXN N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase activity|N-succinyl-L-alpha,epsilon-diaminopimelic acid deacylase activity Catalysis of the reaction: N-succinyl-LL-2,6-diaminopimelate + H(2)O = LL-2,6-diaminopimelate + succinate. GO:0009013 succinate-semialdehyde dehydrogenase [NAD(P)+] activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009013 MetaCyc:SUCCSEMIALDDEHYDROG-RXN|UM-BBD_reactionID:r0371|EC:1.2.1.16 succinate-semialdehyde:NAD(P)+ oxidoreductase activity|succinate semialdehyde dehydrogenase (nicotinamide adenine dinucleotide (phosphate)) Catalysis of the reaction: succinate semialdehyde + NAD(P)+ + H2O = succinate + NAD(P)H + H+. GO:0009012 aminoglycoside 3''-adenylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009012 EC:2.7.7.47|MetaCyc:STREPTOMYCIN-3-ADENYLYLTRANSFERASE-RXN|KEGG_REACTION:R02226|RHEA:20245 AAD (3'')|ATP:streptomycin 3''-adenylyltransferase activity|streptomycin 3''-adenylyltransferase activity Catalysis of the reaction: ATP + streptomycin = 3''-adenylylstreptomycin + diphosphate + H(+). GO:0009011 starch synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009011 MetaCyc:GLYCOGENSYN-RXN|EC:2.4.1.21 ADP-glucose--starch glucosyltransferase activity|ADP-glucose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity|ADPG-starch glucosyltransferase activity|glycogen synthase activity|adenosine diphosphate glucose-starch glucosyltransferase activity|ADPG starch synthetase activity|ADP-glucose starch synthase activity|starch synthetase activity|ADPglucose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity|ADP-glucose transglucosylase activity|adenosine diphosphoglucose-starch glucosyltransferase activity|starch (bacterial glycogen) synthase activity|ADPglucose-starch glucosyltransferase activity Catalysis of the reaction: ADP-glucose + (1,4)-alpha-D-glucosyl(n) = ADP + (1,4)-alpha-D-glucosyl(n+1). GO:0009021 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009021 GO:0009020 tRNA (guanosine-2'-O-)-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009020 EC:2.1.1.34|Reactome:R-HSA-9024161|RHEA:20077|MetaCyc:2.1.1.34-RXN tRNA (Gm18) 2'-O-methyltransferase activity|tRNA (guanosine 2')-methyltransferase activity|S-adenosyl-L-methionine:tRNA (guanosine-2'-O-)-methyltransferase activity|transfer ribonucleate guanosine 2'-methyltransferase activity|tRNA guanosine 2'-methyltransferase activity|S-adenosyl-L-methionine:tRNA guanosine-2'-O-methyltransferase activity|tRNA (Gm18) methyltransferase activity|tRNA guanosine-2'-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 2'-O-methylguanosine. GO:0010001 glial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010001 neuroglia differentiation|glia cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a glial cell. GO:0010000 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010000 GO:0010003 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010003 GO:0010002 cardioblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010002 cardioblast cell differentiation|cardiomyocyte generation|cardiac precursor cell differentiation The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. GO:0010005 cortical microtubule, transverse to long axis biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0010005 Arrays of microtubules underlying and connected to the plasma membrane, in the cortical cytosol, oriented mainly with their axes transverse to the long axis of the cell (and root in plants). In plants it influences the direction of cellulose microfibril deposition. GO:0010004 gastrulation involving germ band extension biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010004 A complex and coordinated series of cellular movements, including germ band extension, that occurs at the end of cleavage during embryonic development. An example of this process is found in Drosophila melanogaster. GO:0097599 xylanase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097599 xylosidase activity Catalysis of the hydrolysis of xylans, homopolysaccharides composed of xylose residues. GO:0009029 tetraacyldisaccharide 4'-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009029 RHEA:20700|KEGG_REACTION:R04657|EC:2.7.1.130|MetaCyc:TETRAACYLDISACC4KIN-RXN lipid-A 4'-kinase activity|ATP:2,3,2',3'-tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-beta-D-1,6-glucosaminyl-beta-phosphate 4'-O-phosphotransferase activity Catalysis of the reaction: 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-(1->6)-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + ATP = ADP + 2 H(+) + lipid IV(a). GO:0010018 far-red light signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010018 far red signaling pathway|far red light signalling pathway|far-red light signal transduction The series of molecular signals initiated upon sensing of far red light by a photoreceptor molecule. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs. GO:0009028 tartronate-semialdehyde synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009028 EC:4.1.1.47|MetaCyc:GLYOCARBOLIG-RXN|RHEA:10136|KEGG_REACTION:R00013 glyoxylic carbo-ligase activity|glyoxylate carboligase activity|glyoxylate carbo-ligase activity|glyoxalate carboligase activity|hydroxymalonic semialdehyde carboxylase activity|tartronic semialdehyde carboxylase activity|glyoxylate carboxy-lyase (dimerizing; tartronate-semialdehyde-forming)|tartronate semialdehyde carboxylase activity|glyoxylate carboxy-lyase (dimerizing) Catalysis of the reaction: 2 glyoxylate + H(+) = 2-hydroxy-3-oxopropanoate + CO(2). GO:0010017 red or far-red light signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010017 red or far-red light signal transduction|phytochrome signaling pathway|red or far red light signaling pathway|red or far-red light signalling pathway|red/far red light signaling pathway The series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs. CHEBI:133867 4-O-[di(2R)-1-glycerylphosphonato]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl undecaprenyl diphosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133867 GO:0009027 tartrate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009027 RHEA:15209|EC:1.1.1.93|MetaCyc:TARTRATE-DEHYDROGENASE-RXN mesotartrate dehydrogenase activity|tartrate:NAD+ oxidoreductase activity Catalysis of the reaction: tartrate + NAD+ = oxaloglycolate + NADH + H+. GO:0009026 tagaturonate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009026 EC:1.1.1.58|KEGG_REACTION:R02555|RHEA:17813|MetaCyc:ALTRO-OXIDOREDUCT-RXN altronate oxidoreductase activity|D-tagaturonate reductase activity|altronic oxidoreductase activity|D-altronate:NAD+ 3-oxidoreductase activity|tagaturonate dehydrogenase activity|altronate dehydrogenase activity|TagUAR Catalysis of the reaction: D-altronate + NAD(+) = D-tagaturonate + H(+) + NADH. GO:0010019 chloroplast-nucleus signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010019 chloroplast-nucleus signalling pathway The process in which a molecular signal is transduced between the chloroplast and nucleus, such that expression of nuclear encoding photosynthetic proteins is coupled with chloroplast biogenesis. GO:0009025 tagatose-bisphosphate aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009025 MetaCyc:TAGAALDOL-RXN|RHEA:22948|KEGG_REACTION:R01069|EC:4.1.2.40 AgaZ|AgaY|D-tagatose-1,6-bisphosphate D-glyceraldehyde 3-phosphate-lyase (glycerone-phosphate-forming)|tagatose-1,6-bisphosphate aldolase 1|tagatose 1,6-diphosphate aldolase activity|D-tagatose-1,6-bisphosphate triosephosphate lyase activity|KbaY|D-tagatose-1,6-bisphosphate aldolase activity Catalysis of the reaction: D-tagatose 1,6-diphosphate = D-glyceraldehyde 3-phosphate + glycerone phosphate. GO:0009024 tagatose-6-phosphate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009024 MetaCyc:TAGAKIN-RXN|RHEA:12420|EC:2.7.1.144 phosphotagatokinase activity|ATP:D-tagatose-6-phosphate 1-phosphotransferase activity Catalysis of the reaction: ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate. GO:0009023 obsolete tRNA sulfurtransferase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009023 tRNA sulphurtransferase activity|tRNA sulfurtransferase OBSOLETE. Catalysis of the reaction: L-cysteine + activated-tRNA = L-serine + tRNA containing a thionucleotide. GO:0009022 tRNA nucleotidyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009022 RHEA:10628|EC:2.7.7.56|MetaCyc:TRNA-NUCLEOTIDYLTRANSFERASE-RXN RNase PH activity|phosphate-dependent exonuclease activity|tRNA:phosphate nucleotidyltransferase activity|ribonuclease PH activity Catalysis of the reaction: tRNA(n+1) + phosphate = tRNA(n) + a nucleoside diphosphate. GO:0009032 thymidine phosphorylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009032 RHEA:16037|EC:2.4.2.4|MetaCyc:THYM-PHOSPH-RXN deoxythymidine phosphorylase activity|thymidine:phosphate deoxy-alpha-D-ribosyltransferase activity|gliostatins|pyrimidine deoxynucleoside phosphorylase activity|blood platelet-derived endothelial cell growth factor|pyrimidine phosphorylase activity|thymidine-orthophosphate deoxyribosyltransferase activity|animal growth regulators, blood platelet-derived endothelial cell growth factors|thymidine:phosphate deoxy-D-ribosyltransferase activity Catalysis of the reaction: thymidine + phosphate = thymine + 2-deoxy-D-ribose 1-phosphate. CHEBI:133860 polyunsaturated hydroxylipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133860 GO:0010010 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010010 GO:0009031 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009031 GO:0009030 thiamine-phosphate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009030 MetaCyc:THI-P-KIN-RXN|KEGG_REACTION:R00617|RHEA:15913|EC:2.7.4.16 thiamin-phosphate kinase activity|thiamin-monophosphate kinase activity|thiamin monophosphatase activity|thiamine-monophosphate kinase activity|thiamin phosphate kinase activity|ATP:thiamine-phosphate phosphotransferase activity|thiamin monophosphokinase activity Catalysis of the reaction: ATP + thiamine phosphate = ADP + H(+) + thiamine diphosphate. GO:0010012 steroid 22-alpha hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010012 Catalysis of the reaction: 5-alpha-campestanaol + O2 = 6-deoxocathasterone + H2O. GO:0010011 auxin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010011 auxin receptor Interacting selectively and non-covalently with auxin, plant hormones that regulate aspects of plant growth. GO:0010014 meristem initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010014 Initiation of a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation, thereby effecting growth and development of a plant by giving rise to more meristem or specialized tissue. GO:0010013 N-1-naphthylphthalamic acid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0010013 Interacting selectively and non-covalently with N-1-naphthylphthalamic acid, an auxin transport inhibitor. GO:0010016 shoot system morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010016 shoot morphogenesis The process in which the anatomical structures of the shoot are generated and organized. The shoot is the part of a seed plant body that is usually above ground. GO:0010015 root morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010015 The process in which the anatomical structures of roots are generated and organized. The root is the usually underground part of a seed plant body that originates from the hypocotyl, functions as an organ of absorption, aeration, and food storage or as a means of anchorage and support. GO:0097574 lateral part of cell biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097574 The region of a polarized cell other than its tips or ends (in some cell types, one end may be called the apex and the other the base). For example, in a polarized epithelial cell, the lateral part includes the cell sides which interface adjacent cells. GO:0097573 glutathione oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097573 Catalysis of the reaction: protein-S-S-glutathione + glutathione-SH = protein-SH + glutathione-S-S-glutathione. GO:0097576 vacuole fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097576 Merging of two or more vacuoles, or of vacuoles and vesicles within a cell to form a single larger vacuole. GO:0097575 lateral cell cortex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097575 The region directly beneath the plasma membrane of the lateral portion of the cell. GO:0097570 cyst wall biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097570 The specialized envelope lying outside the cell membrane of a cyst. A cyst is a resting or dormant stage of a microorganism, usually a bacterium or a protist or rarely an invertebrate animal, that helps the organism to survive in unfavorable environmental conditions. In protists such as protozoan parasites alternating cystic- and non-cystic stages, the cyst wall is usually composed of carbohydrates and proteins. GO:0097572 right nucleus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097572 One of the two nuclei found in Giardia species (trophozoite stage). It is located on the right side of the cell when viewed from the dorsal side. GO:0097571 left nucleus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097571 One of the two nuclei found in Giardia species (trophozoite stage). It is located on the left side of the cell when viewed from the dorsal side. CHEBI:24183 galloyl beta-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24183 CHEBI:48153 D-erythrose 4-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48153 CHEBI:48154 sulfur oxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48154 CHEBI:24190 gamma-glutamyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24190 GO:0097578 sequestering of copper ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097578 retention of copper ion|storage of copper ion|copper ion sequestering|copper ion retention|sequestration of copper ion|copper ion storage|copper ion sequestration The process of binding or confining copper ions such that they are separated from other components of a biological system. GO:0097577 sequestering of iron ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097577 iron ion sequestration|retention of iron ion|iron ion sequestering|storage of iron ion|iron ion retention|sequestration of iron ion|iron ion storage The process of binding or confining iron ions such that they are separated from other components of a biological system. GO:0097579 extracellular sequestering of copper ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097579 extracellular copper ion retention|extracellular retention of copper ion|extracellular copper ion storage|extracellular storage of copper ion|extracellular copper ion sequestering|extracellular copper ion sequestration|extracellular sequestration of copper ion The process of binding or confining copper ions in an extracellular area such that they are separated from other components of a biological system. GO:0097585 dolichyl-phosphate-mannose-protein mannosyltransferase Pmt5p-Pmt3p dimer complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097585 Pmt5p-Pmt3p complex A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt5p-Pmt3p. GO:0097584 dolichyl-phosphate-mannose-protein mannosyltransferase Pmt5p-Pmt2p dimer complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097584 Pmt5p-Pmt2p complex A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt5p-Pmt2p. GO:0097587 MutLgamma complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097587 A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In S. cerevisiae the complex consists of two subunits, Mlh1 and Mlh3. GO:0097586 dolichyl-phosphate-mannose-protein mannosyltransferase Pmt4p homodimer complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097586 Pmt4p-Pmt4p complex|dolichyl-phosphate-mannose-protein mannosyltransferase Pmt4p dimer|dolichyl-phosphate-mannose-protein mannosyltransferase Pmt4p-Pmt4p dimer complex A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt4p. GO:0097581 lamellipodium organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097581 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lamellipodium. A lamellipodium is a thin sheetlike process extended by the leading edge of a crawling fibroblast; contains a dense meshwork of actin filaments. GO:0097580 intracellular sequestering of copper ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097580 intracellular copper ion storage|intracellular retention of copper ion|intracellular storage of copper ion|intracellular copper ion sequestration|intracellular copper ion sequestering|intracellular sequestration of copper ion|intracellular copper ion retention The process of binding or confining copper ions in an intracellular area such that they are separated from other components of a biological system. GO:0009009 site-specific recombinase activity biolink:MolecularActivity go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0009009 Catalysis of the formation of new phosphodiester bonds between a pair of short, unique DNA target sequences. GO:0097583 dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt3p dimer complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097583 Pmt1p-Pmt3p complex A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt1p-Pmt3p. GO:0097582 dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt2p dimer complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097582 Pmt1p-Pmt2p complex A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt1p-Pmt2p. GO:0009008 DNA-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009008 Reactome:R-HSA-5227490 DNA methylase|deoxyribonucleic acid modification methylase activity|DNA transmethylase activity|deoxyribonucleic acid methylase activity|deoxyribonucleate methyltransferase activity|DNA methyltransferase activity|deoxyribonucleate methylase activity|Type II DNA methylase|deoxyribonucleic acid methyltransferase activity Catalysis of the transfer of a methyl group to a DNA molecule. GO:0009007 site-specific DNA-methyltransferase (adenine-specific) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009007 MetaCyc:2.1.1.72-RXN|EC:2.1.1.72|RHEA:15197 modification methylase activity|restriction-modification system activity|DNA adenine methylase|N-6 adenine-specific DNA methylase activity|EcoRI methylase Catalysis of the reaction: S-adenosyl-L-methionine + DNA adenine = S-adenosyl-L-homocysteine + DNA 6-methylaminopurine. CHEBI:24195 gamma-glutamylcysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24195 GO:0009006 obsolete siroheme synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009006 siroheme synthase activity|sirohaem synthase activity OBSOLETE. (Was not defined before being made obsolete). GO:0009005 obsolete signal peptidase II activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009005 lipoprotein signal peptidase activity|signal peptidase II activity|premurein-leader peptidase activity|premurein leader proteinase activity|SPase II activity|prolipoprotein signal peptidase activity|leader peptidase II|prolipoprotein-signal peptidase activity OBSOLETE. Catalysis of the cleavage of N-terminal leader sequences from membrane prolipoproteins. Hydrolyzes the terminal bond of Xaa-Xbb-Xbb-Cys, in which Xaa is hydrophobic (preferably Leu), Xbb is often Ser or Ala, Xcc is often Gly or Ala, and the Cys is alkylated on sulfur with a diacylglyceryl group. GO:0009004 obsolete signal peptidase I activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009004 HOSP|signalase activity|signal peptidase I activity|bacterial leader peptidase 1|bacterial leader peptidase I activity|signal peptide hydrolase activity|leader peptide hydrolase activity|eukaryotic signal proteinase|propeptidase activity|prokaryotic signal proteinase|pilin leader peptidase|PuIO prepilin peptidase|leader peptidase I|SPase I activity|Escherichia coli leader peptidase|phage-procoat-leader peptidase activity|prokaryotic leader peptidase|prokaryotic signal peptidase|leader proteinase activity|leader peptidase activity|signal proteinase activity|SPC|eukaryotic signal peptidase OBSOLETE. Catalysis of the cleavage of N-terminal leader sequences from secreted and periplasmic proteins precursor. GO:0009003 obsolete signal peptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009003 signal peptidase activity OBSOLETE. Catalysis of the cleavage of a signal peptide from a protein precursor. CHEBI:48144 cyclosiloxane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48144 GO:0009002 serine-type D-Ala-D-Ala carboxypeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009002 EC:3.4.16.4|MetaCyc:3.4.16.4-RXN DD-transpeptidase activity|D-alanyl-D-alanine-carboxypeptidase activity|D-alanyl carboxypeptidase activity|D-alanyl-D-alanine-cleaving-peptidase activity|DD-carboxypeptidase|DD-peptidase activity|D-alanyl-D-alanine-cleaving peptidase activity|D-alanine carboxypeptidase|D-alanyl-D-alanine carboxypeptidase activity Catalysis of the reaction: (Ac)2-L-Lys-D-alanyl-D-alanine + H2O = (Ac)2-L-Lys-D-alanine + D-alanine. GO:0009001 serine O-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009001 MetaCyc:SERINE-O-ACETTRAN-RXN|KEGG_REACTION:R00586|EC:2.3.1.30|RHEA:24560 acetyl-CoA:L-serine O-acetyltransferase activity|serine acetyltransferase activity|L-serine acetyltransferase activity|serine transacetylase activity|SATase activity Catalysis of the reaction: L-serine + acetyl-CoA = O-acetyl-L-serine + CoA. CHEBI:48145 cyclotetrasiloxane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48145 GO:0009000 selenocysteine lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009000 EC:4.4.1.16|RHEA:11632|MetaCyc:SELENOCYSTEINE-LYASE-RXN|Reactome:R-HSA-2408524 L-selenocysteine selenide-lyase (L-alanine-forming)|selenocysteine reductase activity|selenocysteine beta-lyase activity Catalysis of the reaction: L-selenocysteine + reduced acceptor = hydrogen selenide + L-alanine + acceptor. GO:0009010 sorbitol-6-phosphate 2-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009010 EC:1.1.1.140|RHEA:19837|MetaCyc:SORB6PDEHYDROG-RXN D-sorbitol 6-phosphate dehydrogenase activity|sorbitol-6-P-dehydrogenase activity|glucitol-6-phosphate dehydrogenase activity|D-sorbitol-6-phosphate dehydrogenase activity|D-glucitol-6-phosphate dehydrogenase activity|D-sorbitol-6-phosphate:NAD+ 2-oxidoreductase activity|ketosephosphate reductase activity Catalysis of the reaction: D-sorbitol 6-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+. GO:0097589 archaeal-type flagellum biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097589 archaellum|archaeal flagellum|archaella A non-membrane-bounded organelle superficially similar to a bacterial-type flagellum; they both consist of filaments extending outside the cell, and rotate to propel the cell, but the archaeal flagella (also called archaella) have a unique structure which lacks a central channel. Similar to bacterial type IV pilins, the archaeal flagellins (archaellins) are made with class 3 signal peptides and they are processed by a type IV prepilin peptidase-like enzyme. The archaellins are typically modified by the addition of N-linked glycans which are necessary for proper assembly and/or function. GO:0097588 archaeal or bacterial-type flagellum-dependent cell motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097588 Cell motility due to movement of bacterial- or archaeal-type flagella. CHEBI:48136 xanthosines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48136 CHEBI:24168 galactosylglycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24168 UBERON:0001508 arch of aorta biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001508 aortic arch|arcus aortae|thoracic aorta the convex portion of the aorta between the ascending and descending parts of the aorta; branches from it include the brachiocephalic trunk, the left common carotid artery, and the left subclavian artery; the brachiocephalic trunk further splits to form the right subclavian artery and the right common carotid artery CHEBI:24167 galactosylglycerol phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24167 CHEBI:133812 5(S),6(S)-epoxy-18-hydroxy-(7E,9E,11Z,14Z,16E)-icosapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133812 CHEBI:48131 nonanedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48131 CHEBI:24160 galactosaminyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24160 CHEBI:48132 tetracenomycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48132 CHEBI:24164 galactosyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24164 CHEBI:133819 13-HODE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133819 CHEBI:24163 galactoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24163 UBERON:0001510 skin of knee biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001510 knee zone of skin|zone of skin of knee|knee skin A zone of skin that is part of a knee [Automatically generated definition]. UBERON:0001512 skin of ankle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001512 ankle skin|tarsal region skin|zone of skin of ankle|ankle zone of skin A zone of skin that is part of an ankle [Automatically generated definition]. UBERON:0001511 skin of leg biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001511 zone of skin of leg|leg skin|leg zone of skin A zone of skin that is part of a leg [Automatically generated definition]. PR:000001902 nuclear receptor ROR-gamma biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001902 RORG|nuclear receptor subfamily 1 group F member 3|thymus orphan receptor|nuclear receptor RZR-gamma|RZRG|TOR|NR1F3|Thor|retinoid-related orphan receptor-gamma|RORC A protein that is a translation product of the human RORC gene or a 1:1 ortholog thereof. CHEBI:48125 trihydrogensilicate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48125 CHEBI:48129 benzoisochromanequinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48129 CHEBI:48120 anthracycline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48120 CHEBI:48122 hydrogensilicate(3-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48122 CHEBI:48121 polyene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48121 CHEBI:48124 dihydrogensilicate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48124 CHEBI:24175 galacturonate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24175 CHEBI:24174 galacturonan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24174 CHEBI:48123 silicate ion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48123 CHEBI:63701 (-)-alpha-cuprenene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63701 CHEBI:133820 9-HODE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133820 CHEBI:63704 (+)-Tau-muurolol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63704 CHEBI:63703 (-)-delta-cadinene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63703 CHEBI:63702 avermitilol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63702 CHEBI:63709 bicyclogermacrene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63709 CHEBI:63708 isopimara-8(14),15-diene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63708 CHEBI:63707 syn-labda-8(17),12E,14-triene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63707 UBERON:0001500 muscle of manus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001500 manus muscle organ|muscle of hand|hand muscle|manus muscle|muscle organ of manus Any muscle organ that is part of a manus [Automatically generated definition]. CHEBI:24148 galactonate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24148 CHEBI:48117 1-glycosylimidazole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48117 CHEBI:48116 nucleotide-amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48116 CHEBI:24145 galactoglycerolipid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24145 CHEBI:24149 galactonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24149 CHEBI:24144 galactoglucomannan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24144 CHEBI:48110 trinitrobenzene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48110 CHEBI:48113 1,3,5-trinitrobenzene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48113 CHEBI:63712 baruol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63712 CHEBI:63711 sesquithujene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63711 CHEBI:63710 7-epi-sesquithujene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63710 CHEBI:63715 8-oxo-dGDP(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63715 NCBITaxon:71193 Elateroidea organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_71193 CHEBI:63714 7-methylguanosine 5'-diphosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63714 CHEBI:38785 morpholines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38785 CHEBI:38784 oxetanes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38784 CHEBI:24158 galactosaminoglycan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24158 CHEBI:24156 galactosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24156 CHEBI:48107 nitric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48107 CHEBI:48109 nitrobenzenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48109 CHEBI:24151 galactooligosaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24151 CHEBI:24150 galactonolactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24150 CHEBI:24155 galactosamine sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24155 CHEBI:24154 galactosamine phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24154 CHEBI:38797 dihydropterin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38797 CHEBI:63727 cis-4-hydroxy-L-proline zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63727 CHEBI:63726 neuroprotective agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63726 CHEBI:63729 7-methylguanosine 5'-diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63729 CHEBI:63728 8-oxo-dGDP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63728 CHEBI:38796 pteroates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38796 CHEBI:38795 pteroic acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38795 CHEBI:38794 pteroic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38794 CHEBI:38793 pteroate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38793 GO:0048585 negative regulation of response to stimulus biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0048585 downregulation of response to stimulus|down regulation of response to stimulus|inhibition of response to stimulus|down-regulation of response to stimulus Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. GO:0048584 positive regulation of response to stimulus biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0048584 upregulation of response to stimulus|stimulation of response to stimulus|up-regulation of response to stimulus|activation of response to stimulus|up regulation of response to stimulus Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. GO:0048583 regulation of response to stimulus biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0048583 Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. GO:0097510 base-excision repair, AP site formation via deaminated base removal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097510 A base-excision repair, AP site formation process occurring via excision of a deaminated base. GO:0048582 positive regulation of post-embryonic development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048582 upregulation of post-embryonic development|stimulation of post-embryonic development|up-regulation of post-embryonic development|activation of post-embryonic development|up regulation of post-embryonic development Any process that activates or increases the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. GO:0048581 negative regulation of post-embryonic development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048581 down-regulation of post-embryonic development|downregulation of post-embryonic development|down regulation of post-embryonic development|inhibition of post-embryonic development Any process that stops, prevents, or reduces the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. GO:0048580 regulation of post-embryonic development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048580 Any process that modulates the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. GO:1903989 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1903989 GO:1903988 iron ion export across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903988 iron cation export|ferrous iron export|iron(2+) export|ferrous iron export across plasma membrane The directed movement of iron ions from inside of a cell, across the plasma membrane and into the extracellular region. GO:1903985 regulation of intestinal D-glucose absorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903985 Any process that modulates the frequency, rate or extent of intestinal D-glucose absorption. GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903984 up-regulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|up-regulation of TRAIL-induced apoptotic signaling pathway|up-regulation of TRAIL-activated extrinsic apoptotic signaling pathway|upregulation of TRAIL-activated apoptotic signaling pathway|upregulation of TRAIL-induced apoptotic signaling pathway|upregulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|upregulation of TRAIL-activated extrinsic apoptotic signaling pathway|up regulation of TRAIL-activated apoptotic signaling pathway|activation of TRAIL-activated apoptotic signaling pathway|up regulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|up regulation of TRAIL-induced apoptotic signaling pathway|positive regulation of TRAIL-induced apoptotic signaling pathway|activation of TRAIL-induced apoptotic signaling pathway|positive regulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|activation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|up regulation of TRAIL-activated extrinsic apoptotic signaling pathway|positive regulation of TRAIL-activated extrinsic apoptotic signaling pathway|activation of TRAIL-activated extrinsic apoptotic signaling pathway|up-regulation of TRAIL-activated apoptotic signaling pathway Any process that activates or increases the frequency, rate or extent of TRAIL-activated apoptotic signaling pathway. GO:0048589 developmental growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048589 The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another. GO:0048588 developmental cell growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048588 developmental growth of a unicellular organism The growth of a cell, where growth contributes to the progression of the cell over time from one condition to another. GO:1903983 positive regulation of microvillus length biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903983 up regulation of regulation of microvillus length|upregulation of regulation of microvillus length|activation of regulation of microvillus length|up-regulation of regulation of microvillus length A process that increases the length of a microvillus. GO:0048587 regulation of short-day photoperiodism, flowering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048587 Any process that modulates the frequency, rate or extent of short-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase. GO:1903982 negative regulation of microvillus length biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903982 down-regulation of regulation of microvillus length|downregulation of regulation of microvillus length|down regulation of regulation of microvillus length|inhibition of regulation of microvillus length A process that decreases the length of a microvillus. GO:1903981 enterobactin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1903981 siderophore binding|enterochelin binding Interacting selectively and non-covalently with enterobactin. GO:0048586 regulation of long-day photoperiodism, flowering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048586 Any process that modulates the frequency, rate or extent of long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase. GO:1903991 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1903991 GO:1903990 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1903990 CHEBI:73092 1-tetradecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73092 GO:0097519 DNA recombinase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097519 A protein-DNA complex consisting of a higher-order oligomer of strand exchange proteins (recombinases) on single-stranded DNA. CHEBI:73091 1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73091 GO:0097516 microvillar actin bundle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097516 A parallel bundle of actin filaments at the core of a microvillus. GO:0097515 asexual spore wall biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097515 A specialized envelope lying outside the cell membrane of a spore derived from an asexual process. Examples of this process are found in bacterial and fungal species. SO:0000714 nucleotide_motif biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000714 nucleotide motif|INSDC_note:nucleotide_motif|INSDC_feature:misc_feature A region of nucleotide sequence corresponding to a known motif. GO:0097518 parallel actin filament bundle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097518 An actin filament bundle in which the filaments are tightly packed (approximately 10-20 nm apart) and oriented with the same polarity. GO:0097517 contractile actin filament bundle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097517 An actin filament bundle in which the filaments are loosely packed (approximately 30-60 nm apart) and arranged with opposing polarities; the loose packing allows myosin (usually myosin-II) to enter the bundle. SO:0000713 DNA_motif biolink:SequenceFeature go-plus http://purl.obolibrary.org/obo/SO_0000713 http://en.wikipedia.org/wiki/DNA_motif DNA motif A motif that is active in the DNA form of the sequence. GO:0097512 cardiac myofibril biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097512 A cardiac myofibril is a myofibril specific to cardiac muscle cells. GO:0097511 dendritic cell dendrite biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097511 A branched cellular projection (or cytoplasmic extension) that is extended from the surface of a dendritic immune cell, and which enables the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells. GO:0097514 sexual spore wall biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097514 A specialized envelope lying outside the cell membrane of a spore derived from a product of meiosis. PO:0025499 sepal epidermis giant cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025499 がく片表皮巨大細胞 (Japanese, exact)|giant cell (broad) An epidermal pavement cell (PO:0000332) that is part of sepal epidermis (PO:0006040) and is approximately one fifth the length of a sepal. GO:0097513 myosin II filament biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097513 A bipolar filament composed of myosin II molecules. PO:0025498 cardinal part of multi-tissue plant structure biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025498 複数の組織からなる植物構造の基本（主要）部分 (Japanese, exact)|parte cardinal de estructura vegetal con múltiples tejidos (Spanish, exact) A plant structure (PO:0009011) that is a proper part of a multi-tissue plant structure (PO:0025496) and includes portions of plant tissues (PO:0009007) of at least two different types. GO:0048596 embryonic camera-type eye morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048596 embryonic eye morphogenesis The process in which the anatomical structures of the eye are generated and organized during embryonic development. PO:0025497 collective plant structure biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025497 estructura vegetal colectiva (Spanish, exact)|集合的植物構造 (Japanese, exact) A plant structure (PO:0009011) that is a proper part of a whole plant (PO:0000003) and includes two or more adjacent plant organs (PO:0009008) or adjacent cardinal organ parts (PO:0025001), along with any associated portions of plant tissue (PO:0009007). GO:0048595 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048595 PO:0025496 multi-tissue plant structure biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025496 estructura vegetal con múltiples tejidos (Spanish, exact)|複数の組織からなる植物構造 (Japanese, exact) A plant structure (PO:0009011) that has as parts two or more portions of plant tissue (PO:0009007) of at least two different types and which through specific morphogenetic processes forms a single structural unit demarcated by primarily bona-fide boundaries from other structural units of different types. GO:0048594 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048594 GO:0097521 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0097521 GO:0097520 nucleotide-excision repair, preincision complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097520 UvrA(2)B(2) complex|UvrA(2)-UvrB(2) complex|UvrB dimer A multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage. GO:0048593 camera-type eye morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048593 camera-style eye morphogenesis The process in which the anatomical structures of the eye are generated and organized. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field. GO:0048592 eye morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048592 The process in which the anatomical structures of the eye are generated and organized. GO:0048591 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048591 GO:0048590 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048590 PO:0025490 plant ovary ovule biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025490 óvulo del ovario (Spanish, exact)|子房胚珠 (Japanese, exact) A plant ovule (PO:0020006) that is part of a plant ovary (PO:0009072). GO:1903999 negative regulation of eating behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903999 down regulation of eating behavior|inhibition of eating behaviour|downregulation of eating behavior|down-regulation of eating behavior|down-regulation of eating behaviour|negative regulation of eating behaviour|inhibition of eating behavior|downregulation of eating behaviour|down regulation of eating behaviour Any process that stops, prevents or reduces the frequency, rate or extent of eating behavior. GO:1903998 regulation of eating behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903998 regulation of eating behaviour Any process that modulates the frequency, rate or extent of eating behavior. GO:1903997 positive regulation of non-membrane spanning protein tyrosine kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903997 activation of janus kinase 1 activity|up regulation of p60c-src protein tyrosine kinase activity|activation of janus kinase 2 activity|activation of janus kinase 3 activity|activation of cytoplasmic protein tyrosine kinase activity|positive regulation of p60c-src protein tyrosine kinase activity|up-regulation of non-membrane spanning protein tyrosine kinase activity|activation of non-membrane spanning protein tyrosine kinase activity|up-regulation of janus kinase 1 activity|up-regulation of janus kinase 2 activity|positive regulation of cytoplasmic protein tyrosine kinase activity|upregulation of focal adhesion kinase activity|up regulation of Bruton's tyrosine kinase activity|up-regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|up-regulation of janus kinase 3 activity|activation of p60c-src protein tyrosine kinase activity|up-regulation of non-specific protein-tyrosine kinase activity|up regulation of cytoplasmic protein tyrosine kinase activity|positive regulation of Bruton's tyrosine kinase activity|up-regulation of p60c-src protein tyrosine kinase activity|activation of Bruton's tyrosine kinase activity|upregulation of janus kinase 1 activity|upregulation of janus kinase 2 activity|up-regulation of focal adhesion kinase activity|upregulation of janus kinase 3 activity|upregulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|up regulation of non-membrane spanning protein tyrosine kinase activity|upregulation of non-specific protein-tyrosine kinase activity|upregulation of cytoplasmic protein tyrosine kinase activity|up-regulation of Bruton's tyrosine kinase activity|activation of focal adhesion kinase activity|upregulation of p60c-src protein tyrosine kinase activity|up regulation of janus kinase 1 activity|up regulation of janus kinase 2 activity|up regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|positive regulation of janus kinase 1 activity|up regulation of janus kinase 3 activity|positive regulation of focal adhesion kinase activity|upregulation of non-membrane spanning protein tyrosine kinase activity|activation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|up regulation of non-specific protein-tyrosine kinase activity|positive regulation of janus kinase 2 activity|up-regulation of cytoplasmic protein tyrosine kinase activity|positive regulation of janus kinase 3 activity|positive regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|up regulation of focal adhesion kinase activity|activation of non-specific protein-tyrosine kinase activity|positive regulation of non-specific protein-tyrosine kinase activity|upregulation of Bruton's tyrosine kinase activity Any process that activates or increases the frequency, rate or extent of non-membrane spanning protein tyrosine kinase activity. GO:1903996 negative regulation of non-membrane spanning protein tyrosine kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903996 negative regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|down-regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|downregulation of focal adhesion kinase activity|negative regulation of janus kinase 2 activity|down-regulation of janus kinase 2 activity|negative regulation of non-specific protein-tyrosine kinase activity|negative regulation of janus kinase 3 activity|down-regulation of janus kinase 3 activity|down-regulation of non-specific protein-tyrosine kinase activity|down regulation of Bruton's tyrosine kinase activity|negative regulation of cytoplasmic protein tyrosine kinase activity|down-regulation of cytoplasmic protein tyrosine kinase activity|down regulation of focal adhesion kinase activity|downregulation of Bruton's tyrosine kinase activity|inhibition of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|negative regulation of p60c-src protein tyrosine kinase activity|down-regulation of p60c-src protein tyrosine kinase activity|inhibition of non-specific protein-tyrosine kinase activity|inhibition of focal adhesion kinase activity|down-regulation of non-membrane spanning protein tyrosine kinase activity|inhibition of janus kinase 1 activity|inhibition of janus kinase 2 activity|downregulation of cytoplasmic protein tyrosine kinase activity|inhibition of janus kinase 3 activity|negative regulation of Bruton's tyrosine kinase activity|down-regulation of Bruton's tyrosine kinase activity|down regulation of cytoplasmic protein tyrosine kinase activity|down regulation of janus kinase 1 activity|inhibition of p60c-src protein tyrosine kinase activity|down regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|down regulation of janus kinase 2 activity|down regulation of janus kinase 3 activity|down regulation of non-specific protein-tyrosine kinase activity|downregulation of non-membrane spanning protein tyrosine kinase activity|downregulation of janus kinase 1 activity|downregulation of janus kinase 2 activity|negative regulation of focal adhesion kinase activity|downregulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|down-regulation of focal adhesion kinase activity|inhibition of cytoplasmic protein tyrosine kinase activity|down regulation of non-membrane spanning protein tyrosine kinase activity|downregulation of janus kinase 3 activity|downregulation of non-specific protein-tyrosine kinase activity|down regulation of p60c-src protein tyrosine kinase activity|inhibition of Bruton's tyrosine kinase activity|inhibition of non-membrane spanning protein tyrosine kinase activity|downregulation of p60c-src protein tyrosine kinase activity|down-regulation of janus kinase 1 activity|negative regulation of janus kinase 1 activity Any process that stops, prevents or reduces the frequency, rate or extent of non-membrane spanning protein tyrosine kinase activity. GO:1903995 regulation of non-membrane spanning protein tyrosine kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903995 regulation of focal adhesion kinase activity|regulation of Bruton's tyrosine kinase activity|regulation of cytoplasmic protein tyrosine kinase activity|regulation of janus kinase 1 activity|regulation of janus kinase 2 activity|regulation of ATP:protein-tyrosine O-phosphotransferase activity|regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|regulation of janus kinase 3 activity|regulation of non-specific protein-tyrosine kinase activity|regulation of p60c-src protein tyrosine kinase activity Any process that modulates the frequency, rate or extent of non-membrane spanning protein tyrosine kinase activity. GO:1903994 obsolete positive regulation of protein stabilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903994 up regulation of protein sequestering|up-regulation of lysosomal protein stabilization|upregulation of protein stabilization|up-regulation of protein stabilization activity|positive regulation of positive regulation of protein stability|upregulation of lysosomal protein stabilization|upregulation of protein sequestering|up regulation of protein stabilization|up regulation of positive regulation of protein stability|activation of protein stabilization|activation of protein stabilization activity|up-regulation of protein sequestering|up regulation of lysosomal protein stabilization|positive regulation of protein stabilization activity|upregulation of positive regulation of protein stability|positive regulation of lysosomal protein stabilization|up regulation of protein stabilization activity|up-regulation of protein stabilization|activation of protein sequestering|activation of lysosomal protein stabilization|positive regulation of protein stabilization|positive regulation of protein sequestering|up-regulation of positive regulation of protein stability|upregulation of protein stabilization activity|activation of positive regulation of protein stability OBSOLETE. Any process that activates or increases the frequency, rate or extent of protein stabilization. GO:0048599 oocyte development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048599 The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. GO:1903993 obsolete negative regulation of protein stabilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903993 negative regulation of protein stabilization|inhibition of protein stabilization activity|downregulation of protein sequestering|down regulation of protein stabilization|inhibition of lysosomal protein stabilization|down-regulation of positive regulation of protein stability|negative regulation of positive regulation of protein stability|down regulation of protein sequestering|downregulation of protein stabilization|down regulation of lysosomal protein stabilization|downregulation of positive regulation of protein stability|inhibition of protein sequestering|negative regulation of protein stabilization activity|down-regulation of protein stabilization activity|downregulation of lysosomal protein stabilization|down-regulation of protein stabilization|down regulation of positive regulation of protein stability|inhibition of positive regulation of protein stability|inhibition of protein stabilization|negative regulation of lysosomal protein stabilization|down-regulation of lysosomal protein stabilization|downregulation of protein stabilization activity|down-regulation of protein sequestering|negative regulation of protein sequestering|down regulation of protein stabilization activity OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of protein stabilization. GO:0048598 embryonic morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048598 embryonic anatomical structure morphogenesis The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants. GO:1903992 obsolete regulation of protein stabilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903992 regulation of protein sequestering|regulation of lysosomal protein stabilization|regulation of positive regulation of protein stability|regulation of protein stabilization|regulation of protein stabilization activity OBSOLETE. Any process that modulates the frequency, rate or extent of protein stabilization. GO:0048597 post-embryonic camera-type eye morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048597 post-embryonic eye morphogenesis|post-embryonic camera-style eye morphogenesis The process in which the anatomical structures of the eye are generated and organized during post-embryonic development. GO:0097527 necroptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097527 necroptosis signaling pathway|necroptotic signal transduction|necroptotic signalling pathway|necroptosis signaling A series of molecular signals which triggers the necroptotic death of a cell. The pathway starts with reception of a signal, is characterized by activation of receptor-interacting serine/threonine-protein kinase 1 and/or 3 (RIPK1/3, also called RIP1/3), and ends when the execution phase of necroptosis is triggered. GO:0097526 spliceosomal tri-snRNP complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097526 A spliceosomal snRNP complex that is formed by the association of the U4/U6 (or U4atac/U6atac) snRNP with the U5 snRNP. GO:0097529 myeloid leukocyte migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097529 The movement of a myeloid leukocyte within or between different tissues and organs of the body. GO:0097528 execution phase of necroptosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097528 necroptotic execution phase|execution phase of necroptotic process|necroptosis A stage of the necroptotic process that starts after a necroptotic signal has been relayed to the execution machinery. Key steps of the execution phase are swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. The execution phase ends when the cell has died. GO:0097523 transcription ternary complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097523 transcription protein-DNA-RNA complex A protein-DNA-RNA complex composed of RNA polymerase, template DNA, and an RNA transcript. GO:0097522 protein-DNA ISRE complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097522 A protein-DNA complex formed through interaction of the protein(s) with an interferon-stimulated response element (ISRE) in the DNA. GO:0097525 spliceosomal snRNP complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097525 A small ribonucleoprotein complex involved in formation of the spliceosome. GO:0097524 sperm plasma membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097524 A plasma membrane that is part of a sperm cell. PO:0025487 bract primordium biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025487 portion of bract primordium tissue (exact)|primordio de la bráctea (Spanish, exact)|苞原基（可視的） (Japanese, exact)|bract primordia (exact, plural) A phyllome primordium (PO:0025487) that is committed to the development of a flower bract (PO:0009055). PO:0025486 stamen anlagen biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025486 anlagen del estambre (Spanish, exact)|雄蕊原基 (Japanese, exact) A phyllome anlagen (PO:0025430) that will give rise to a stamen primordium (PO:0004705) and is part of a peripheral zone (PO:000225) of a flower meristem (PO:0000229). PO:0025485 sepal anlagen biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025485 がく片原基 (Japanese, exact)|anlagen del sépalo (Spanish, exact) A phyllome anlagen (PO:0025430) that will give rise to a sepal primordium (PO:0004704) and is part of a peripheral zone (PO:000225) of a flower meristem (PO:0000229). PO:0025484 petal anlagen biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025484 花弁原基 (Japanese, exact)|anlagen del pétalo (Spanish, exact) A phyllome anlagen (PO:0025430) that will give rise to a petal primordium (PO:0000021) and is part of a peripheral zone (PO:000225) of a flower meristem (PO:0000229). PO:0025482 bract anlagen biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025482 anlagen de bráctea (Spanish, exact)|苞原基 (Japanese, exact) A phyllome anlagen (PO:0025430) that will give rise to a bract primordium (PO:0025487) and is part of a peripheral zone (PO:000225) of a reproductive shoot apical meristem (PO:0008028). PO:0025480 shoot-borne root primordium biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025480 primordio del eje del epiblasto de la raíz (Spanish, exact)|portion of shoot-borne root primordium tissue (exact)|adventitious root primordium (broad)|シュート細胞由来の根原基（可視的） (Japanese, exact) A root primordium (PO:0005029) that is committed to the development of a shoot-borne root (PO:0000042). PO:0025478 androecium primordium biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025478 雄蕊群原基(可視的） (Japanese, exact)|portion of androecium primordium tissue (exact)|primordium del androecio (Spanish, exact) A floral structure primordium (PO:0025477) that is committed to the development of an androecium (PO:0009061). PO:0025477 floral organ primordium biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025477 primordio de organo floral (Spanish, exact)|floral structure primordia (exact, plural)|花器官原基 (Japanese, exact)|portion of floral structure primordium tissue (exact) A primordium (PO:0025127) that is committed to the development of a floral organ (PO:0025395) and is part of a reproductive shoot apex (PO:0025222). CL:0001200 lymphocyte of B lineage, CD19-positive biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001200 A lymphocyte of B lineage that is CD19-positive. SO:0000727 CRM biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000727 TF module|transcription factor module|cis regulatory module A regulatory region where transcription factor binding sites are clustered to regulate various aspects of transcription activities. (CRMs can be located a few kb to hundreds of kb upstream of the core promoter, in the coding sequence, within introns, or in the untranslated regions (UTR) sequences, and even on a different chromosome). A single gene can be regulated by multiple CRMs to give precise control of its spatial and temporal expression. CRMs function as nodes in large, intertwined regulatory network. CL:0001202 CD86-positive plasmablast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001202 CD86-positive, CD20-negative plasmablast|CD86+ plasmablast A plasmablast that is CD86-positive. GO:0097509 oxanine DNA N-glycosylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097509 oxanine-DNA glycosylase activity DNA N-glycosylase activity acting on deaminated guanine where the resulting base (oxanine) is generated by NO- or HNO2-induced nitrosative deamination. GO:0097508 xanthine DNA N-glycosylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097508 xanthine-DNA glycosylase activity DNA N-glycosylase activity acting on deaminated guanine (xanthine). CL:0001201 B cell, CD19-positive biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001201 B lymphocyte, CD19-positive|CD19-positive B cell|B-lymphocyte, CD19-positive|CD19+ B cell|B-cell, CD19-positive A B cell that is CD19-positive. GO:0097505 Rad6-Rad18 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097505 A ubiquitin ligase complex found to be involved in post-replicative bypass of UV-damaged DNA and UV mutagenesis. In S. cerevisiae, the complex contains the ubiquitin conjugating enzyme Rad6 and Rad18, a protein containing a RING finger motif and a nucleotide binding motif. The yeast Rad6-Rad18 heterodimer has ubiquitin conjugating activity, binds single-stranded DNA, and possesses single-stranded DNA-dependent ATPase activity. GO:0097504 Gemini of coiled bodies biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097504 Gems Nuclear bodies frequently found near or associated with Cajal bodies (also called coiled bodies or CBs). Gemini of coiled bodies, or 'gems', are similar in size and shape to CBs, and often indistinguishable under the microscope. Unlike CBs, gems do not contain small nuclear ribonucleoproteins (snRNPs); they contain a protein called survivor of motor neurons (SMN) whose function relates to snRNP biogenesis. Gems are believed to assist CBs in snRNP biogenesis, and to play a role in the etiology of spinal muscular atrophy (SMA). GO:0097507 hypoxanthine DNA N-glycosylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097507 hypoxanthine-DNA glycosylase activity DNA N-glycosylase activity acting on deaminated adenine (hypoxanthine). GO:0097506 deaminated base DNA N-glycosylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097506 deaminated base DNA glycosylase activity|DNA glycosylase activity acting on deaminated bases DNA N-glycosylase activity acting on deaminated bases. GO:0097501 stress response to metal ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097501 response to metal toxicity|response to metal ion stress|response to metal ion toxicity|response to excess metal ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a metal ion stimulus. GO:0097500 receptor localization to non-motile cilium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097500 receptor localization to nonmotile primary cilium A process in which a receptor is transported to, or maintained in, a location within a non-motile cilium. GO:0097503 sialylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097503 The covalent attachment of sialic acid to a substrate molecule. GO:0097502 mannosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097502 The covalent attachment of a mannose residue to a substrate molecule. GO:0097552 mitochondrial double-strand break repair via homologous recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097552 mtDSB repair via homologous recombination The repair of a double-strand break in mitochondrial DNA in which the broken DNA molecule is repaired using homologous sequences. GO:0097551 mitochondrial double-strand break repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097551 mtDSB repair The repair of double-strand breaks in mitochondrial DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix. GO:0097554 left anterior flagellum biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097554 left anterior cilium A cilium (also called flagellum) found in Giardia species (trophozoite stage). It originates at the left anterior basal body, extends laterally through the cytoplasm, crosses the right anterior axoneme, and exits as a membrane-bound flagellum on the anterior left side of the cell. GO:0097553 calcium ion transmembrane import into cytosol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097553 calcium transmembrane import into cytosol A process in which a calcium ion is transported from one side of a membrane to the other into the cytosol by means of some agent such as a transporter or pore. GO:0097550 transcription preinitiation complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097550 transcription preinitiation complex|DNA-templated transcriptional preinitiation complex|transcriptional pre-initiation complex|preinitiation complex|PIC|transcriptional preinitiation complex A protein-DNA complex composed of proteins binding promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription. CHEBI:48096 D-glutamic acid residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48096 CHEBI:48095 keto-D-fructose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48095 CHEBI:48097 D-glutamine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48097 CHEBI:133892 4-O-[1-D-ribitylphosphonato-(2R)-1-glycerylphosphonato]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl ditrans,octacis-undecaprenyl diphosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133892 CHEBI:133894 4-O-[poly(1-D-ribitylphosphonato)-1-D-ribitylphosphonato-(2R)-1-glycerylphosphonato]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl ditrans,octacis-undecaprenyl diphosphate polyanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133894 CHEBI:133897 methanesulfinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133897 CHEBI:133896 4-O-({poly[1-D-ribitylphosphonato]}-di{[2R]-1-glycerylphosphonato})-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl ditrans,octacis-undecaprenyl diphosphate polyanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133896 CHEBI:133899 8(S),15(S)-DiHPETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133899 CHEBI:133898 chromopyrrolate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133898 GO:0097559 right ventral flagellum biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097559 right ventral cilium A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the right ventral basal body and exits the cell body proximally and dorsal to the ventral disc. GO:0097556 left posteriolateral flagellum biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097556 left posterolateral cilium|left posterolateral flagellum|left posteriolateral cilium A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the left posteriolateral basal body and extends cytoplasmically toward the cell posterior, marking the left anterior boundary of the lateral shield and the left lateral region of the funis before exiting at the left lateral region of the cell body. GO:0097555 right anterior flagellum biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097555 right anterior cilium A cilium (also called flagellum) found in Giardia species (trophozoite stage). It originates at the right anterior basal body, extends laterally through the cytoplasm, crosses the left anterior axoneme, and exits as a membrane-bound flagellum on the anterior right side of the cell. GO:0097558 left ventral flagellum biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097558 left ventral cilium A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the left ventral basal body and exits the cell body proximally and dorsal to the ventral disc. GO:0097557 right posteriolateral flagellum biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097557 right posterolateral flagellum|right posterolateral cilium|right posteriolateral cilium A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the right posteriolateral basal body and extends cytoplasmically toward the cell posterior, marking the right anterior boundary of the lateral shield and the right lateral region of the funis before exiting at the right lateral region of the cell body. GO:0097563 left middle basal body pair biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097563 Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the caudal and posteriolateral basal bodies located to the right of the left nucleus of the trophozoite when viewed dorsally. GO:0097562 left lateral basal body pair biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097562 Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the anterior and ventral basal bodies located to the right of the left nucleus of the trophozoite when viewed dorsally. GO:0097565 right middle basal body pair biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097565 Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the caudal and posteriolateral basal bodies located to the left of the right nucleus of the trophozoite when viewed dorsally. GO:0097564 right lateral basal body pair biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097564 Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the anterior and ventral basal bodies located to the left of the right nucleus of the trophozoite when viewed dorsally. GO:0097561 right caudal flagellum biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097561 right caudal cilium A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the right caudal basal body, extending cytoplasmically and exiting at the posterior end of the cell body. GO:0097560 left caudal flagellum biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097560 left caudal cilium A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the left caudal basal body, extending cytoplasmically and exiting at the posterior end of the cell body. CHEBI:48092 L-xylonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48092 CHEBI:48094 D-aspartic acid residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48094 CHEBI:48093 D-xylonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48093 GO:0097567 right tetrad biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097567 Set of four basal bodies found in Giardia species (trophozoite stage). It comprises the right lateral basal body pair and the right middle basal body pair (i.e. the anterior, ventral, caudal and posteriolateral basal bodies located to the left of the right nucleus of the trophozoite when viewed dorsally). GO:0097566 left tetrad biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097566 Set of four basal bodies found in Giardia species (trophozoite stage). It comprises the left lateral basal body pair and the left middle basal body pair (i.e. the anterior, ventral, caudal and posteriolateral basal bodies located to the right of the left nucleus of the trophozoite when viewed dorsally). GO:0097569 lateral shield biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097569 Region of the ventral side of the cell body found in Giardia species (trophozoite stage). It is located posterior on either side of the ventral groove; the upper boundary is the ventral disc, and the lower boundary is marked by the posteriolateral flagella. GO:0097568 median body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097568 parabasal body A non-membrane bound, semi-organized microtubule array of unknown function found in Giardia species (trophozoite stage). It is located on the dorsal side of the trophozoite, slightly posterior to the ventral disc. GO:0097530 granulocyte migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097530 The movement of a granulocyte within or between different tissues and organs of the body. GO:0097532 stress response to acid chemical biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097532 response to acid stress|stress response to acid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form. GO:0097531 mast cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097531 The movement of a mast cell within or between different tissues and organs of the body. CHEBI:133872 (2Z,4E)-4-hydroxy-6-oxoocta-2,4-dienedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133872 CHEBI:48081 bacteriocin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48081 CHEBI:48080 brefeldin A biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48080 GO:0097538 ciliary necklace biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097538 cilial necklace|cilium necklace A protein complex located on the cilium membrane in the ciliary transition zone; it is connected to the cilium axoneme via Y-shaped links. GO:0097537 Y-shaped link biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097537 Y-shaped assemblage|Y-shaped linker|Y-link|Y-shaped fibre|membrane-microtubule complex|Y-shaped fiber|Y-link structure A Y-shaped protein complex in the ciliary transition zone that connects the cilium axoneme to the ciliary necklace. Both protein sorting and protein gating occur at this point in the cilium allowing some, but not all proteins to enter the cilium. GO:0097539 ciliary transition fiber biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097539 cilial transition fiber|distal appendage of basal body|cilium transition fibre|centriolar distal appendage|cilium transition fiber|ciliary transition fibre|transition fibre|distal appendage of mother centriole|distal appendage of centriole|cilial transition fibre|transition fiber A nine-bladed, propeller-like protein complex that links the distal end of the basal body and the cilium to the plasma membrane. Functions in protein sorting and gating (i.e. active and passive transport of proteins in and out of the cilium). GO:0097534 lymphoid lineage cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097534 lymphoid lineage restricted progenitor cell migration The orderly movement of a lymphoid lineage cell from one site to another. A lymphoid lineage cell, also called a lymphoid lineage restricted progenitor cell, is a progenitor cell restricted to the lymphoid lineage. GO:0097533 cellular stress response to acid chemical biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097533 cellular response to acid stress|cellular stress response to acid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in cellular homeostasis caused by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form. GO:0097536 thymus epithelium morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097536 thymic epithelium morphogenesis The process in which the thymus epithelium is generated and organized. GO:0097535 lymphoid lineage cell migration into thymus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097535 lymphoid lineage restricted progenitor cell migration into thymus The movement of a lymphoid lineage cell (also called a lymphoid lineage restricted progenitor cell) into the thymus. Lymphoid lineage cells enter and exit the thymus several times as part of this process. GO:0097541 axonemal basal plate biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097541 axoneme basal plate|basal plate Part of the axoneme consisting of a highly electron-dense region at the distal end of the ciliary transition zone within the axonemal lumen at which the axonemal central pair of microtubules is connected to the rest of the axonemal structure. GO:0097540 axonemal central pair biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097540 central pair|axoneme microtubule central pair|central-pair microtubules|axonemal microtubule central pair|axoneme central pair Part of the axoneme consisting of the inner two microtubule doublets of the 9+2 axoneme occurring in most motile cilia. GO:0097543 ciliary inversin compartment biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097543 cilial inversin compartment|flagellum inversin compartment|Inv compartment of the cilium|cilium inversin compartment|flagellar inversin compartment|inversin compartment Proximal part of the ciliary shaft to which the inversin protein (also called Inv) specifically localizes. The inversin compartment appears to have a different protein composition than the rest of the cilium, although there is no structure that separates it form the distal part of the cilium. GO:0097542 ciliary tip biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097542 cilium tip|flagellum tip|cilial tip|flagellar tip Part of the cilium where the axoneme ends. The ciliary tip has been implicated in ciliary assembly and disassembly, as well as signal transduction. CHEBI:48066 D-mannopyranose 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48066 CHEBI:48069 (R)-5-oxo-2,5-dihydro-2-furylacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48069 CHEBI:48068 (S)-5-oxo-2,5-dihydro-2-furylacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48068 CHEBI:133886 FMNH2(3-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133886 CHEBI:48070 12-oxo steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48070 GO:0097549 chromatin organization involved in negative regulation of transcription biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0097549 negative regulation of gene-specific transcription from RNA polymerase II promoter by histone modification|negative regulation of global transcription from Pol II promoter by histone modification|negative regulation of transcription by chromatin organization|negative regulation of transcription from Pol II promoter by histone modification|negative regulation of transcription from RNA polymerase II promoter, global by histone modification|negative regulation of transcription from RNA polymerase II promoter by histone modification Any process that stops, prevents, or reduces the frequency, rate or extent of transcription by chromatin organization. GO:0097548 seed abscission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097548 The controlled shedding of a seed. GO:0097545 axonemal outer doublet biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097545 outer doublet|outer-doublet microtubules|axoneme outer doublet Part of an axoneme consisting in a doublet microtubule. Nine of these outer doublets form the 9+0 axoneme, while the 9+2 axoneme also contains a central pair. Dynein arms attached to the doublets provide the mechanism of movement of the cilium. GO:0097544 ciliary shaft biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097544 cilium shaft|flagellum shaft|cilial shaft|flagellar shaft The mid part of a cilium between the ciliary base and ciliary tip that extends into the extracellular space. GO:0097547 synaptic vesicle protein transport vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097547 STV A cytoplasmic vesicle composed of both tubulovesicular and clear core vesicles that transport synaptic vesicle-associated proteins. Proteins carried by synaptic vesicle protein transport vesicles (STVs) include synaptophysin, synapsin Ia, synaptotagmin and synaptobrevin/vesicle-associated membrane protein 2 (VAMP2). STVs are packaged via the trans-Golgi network before being transported through the axon. GO:0097546 ciliary base biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097546 cilium base|flagellar base|cilial base|flagellum base Area of the cilium (also called flagellum) where the basal body and the axoneme are anchored to the plasma membrane. The ciliary base encompasses the distal part of the basal body, transition fibers and transition zone and is structurally and functionally very distinct from the rest of the cilium. In this area proteins are sorted and filtered before entering the cilium, and many ciliary proteins localize specifically to this area. GO:1903908 positive regulation of plasma membrane raft polarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903908 up-regulation of plasma membrane raft polarization|upregulation of plasma membrane raft polarization|up regulation of plasma membrane raft polarization|activation of plasma membrane raft polarization Any process that activates or increases the frequency, rate or extent of plasma membrane raft polarization. GO:1903907 negative regulation of plasma membrane raft polarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903907 inhibition of plasma membrane raft polarization|down regulation of plasma membrane raft polarization|downregulation of plasma membrane raft polarization|down-regulation of plasma membrane raft polarization Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane raft polarization. GO:1903906 regulation of plasma membrane raft polarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903906 Any process that modulates the frequency, rate or extent of plasma membrane raft polarization. GO:1903905 positive regulation of establishment of T cell polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903905 up-regulation of T lymphocyte polarization|upregulation of establishment of T lymphocyte polarity|up-regulation of T cell polarization|up regulation of T-cell polarization|positive regulation of establishment of T-lymphocyte polarity|activation of T-cell polarization|positive regulation of T-cell polarization|up regulation of establishment of T-lymphocyte polarity|upregulation of establishment of T cell polarity|positive regulation of establishment of T-cell polarity|upregulation of T lymphocyte polarization|up regulation of establishment of T-cell polarity|up-regulation of establishment of T lymphocyte polarity|activation of establishment of T lymphocyte polarity|upregulation of T cell polarization|upregulation of establishment of T-lymphocyte polarity|activation of establishment of T cell polarity|up-regulation of establishment of T cell polarity|up-regulation of T-cell polarization|up regulation of T lymphocyte polarization|activation of T lymphocyte polarization|upregulation of establishment of T-cell polarity|positive regulation of T lymphocyte polarization|up regulation of T cell polarization|positive regulation of establishment of T lymphocyte polarity|activation of T cell polarization|positive regulation of T cell polarization|up-regulation of establishment of T-lymphocyte polarity|up regulation of establishment of T lymphocyte polarity|activation of establishment of T-lymphocyte polarity|upregulation of T-cell polarization|up-regulation of establishment of T-cell polarity|up regulation of establishment of T cell polarity|activation of establishment of T-cell polarity Any process that activates or increases the frequency, rate or extent of establishment of T cell polarity. CHEBI:73017 O-isobutyrylcarnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73017 GO:1903904 negative regulation of establishment of T cell polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903904 downregulation of T-cell polarization|inhibition of establishment of T lymphocyte polarity|negative regulation of establishment of T-cell polarity|down-regulation of establishment of T-cell polarity|down regulation of establishment of T cell polarity|inhibition of T cell polarization|inhibition of establishment of T cell polarity|downregulation of establishment of T-lymphocyte polarity|negative regulation of T-cell polarization|down-regulation of T-cell polarization|down regulation of T lymphocyte polarization|down regulation of establishment of T-lymphocyte polarity|downregulation of establishment of T-cell polarity|inhibition of establishment of T-lymphocyte polarity|down regulation of T cell polarization|downregulation of T lymphocyte polarization|down regulation of establishment of T-cell polarity|inhibition of T-cell polarization|down-regulation of establishment of T lymphocyte polarity|inhibition of establishment of T-cell polarity|negative regulation of establishment of T lymphocyte polarity|downregulation of T cell polarization|down-regulation of establishment of T cell polarity|down-regulation of T lymphocyte polarization|negative regulation of T lymphocyte polarization|downregulation of establishment of T lymphocyte polarity|negative regulation of T cell polarization|down regulation of T-cell polarization|down-regulation of T cell polarization|inhibition of T lymphocyte polarization|down-regulation of establishment of T-lymphocyte polarity|negative regulation of establishment of T-lymphocyte polarity|down regulation of establishment of T lymphocyte polarity|downregulation of establishment of T cell polarity Any process that stops, prevents or reduces the frequency, rate or extent of establishment of T cell polarity. GO:1903903 regulation of establishment of T cell polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903903 regulation of establishment of T-lymphocyte polarity|regulation of T lymphocyte polarization|regulation of establishment of T-cell polarity|regulation of T cell polarization|regulation of establishment of T lymphocyte polarity|regulation of T-cell polarization Any process that modulates the frequency, rate or extent of establishment of T cell polarity. GO:1903902 positive regulation of viral life cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903902 up-regulation of viral infectious cycle|activation of viral replication|activation of lytic viral life cycle|upregulation of viral assembly, maturation, egress, and release|up regulation of viral life cycle|activation of viral infectious cycle|positive regulation of lytic viral life cycle|up-regulation of viral replication|positive regulation of viral infectious cycle|up regulation of lytic viral life cycle|up regulation of viral infectious cycle|upregulation of viral life cycle|up regulation of viral assembly, maturation, egress, and release|positive regulation of viral assembly, maturation, egress, and release|upregulation of viral replication|upregulation of lytic viral life cycle|activation of viral assembly, maturation, egress, and release|upregulation of viral infectious cycle|up-regulation of viral life cycle|activation of viral life cycle|up regulation of viral replication|up-regulation of viral assembly, maturation, egress, and release|positive regulation of viral replication|up-regulation of lytic viral life cycle Any process that activates or increases the frequency, rate or extent of viral life cycle. GO:1903901 negative regulation of viral life cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903901 inhibition of viral assembly, maturation, egress, and release|down-regulation of viral replication|negative regulation of viral replication|down-regulation of lytic viral life cycle|negative regulation of lytic viral life cycle|down-regulation of viral infectious cycle|negative regulation of viral infectious cycle|down regulation of viral assembly, maturation, egress, and release|downregulation of viral life cycle|down regulation of viral life cycle|downregulation of viral assembly, maturation, egress, and release|downregulation of lytic viral life cycle|inhibition of viral life cycle|inhibition of viral replication|downregulation of viral infectious cycle|down regulation of lytic viral life cycle|down regulation of viral infectious cycle|down-regulation of viral assembly, maturation, egress, and release|down regulation of viral replication|negative regulation of viral assembly, maturation, egress, and release|downregulation of viral replication|inhibition of lytic viral life cycle|inhibition of viral infectious cycle|down-regulation of viral life cycle Any process that stops, prevents or reduces the frequency, rate or extent of viral life cycle. GO:1903900 regulation of viral life cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903900 regulation of viral assembly, maturation, egress, and release|regulation of lytic viral life cycle|regulation of viral infectious cycle|regulation of viral replication Any process that modulates the frequency, rate or extent of viral life cycle. GO:0048505 regulation of timing of cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048505 timing of cell differentiation The process controlling the activation and/or rate at which relatively unspecialized cells acquire specialized features. Any process that modulates the rate, frequency or extent of the XXX at a consistent predetermined time point during its development. CHEBI:63693 (2Z,4Z)-2-hydroxyhexa-2,4-dienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63693 GO:0048504 regulation of timing of animal organ formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048504 timing of organ formation|timing of organ biosynthesis Any process that modulates the rate, frequency or extent of animal organ formation at a consistent predetermined time point during development. CHEBI:63692 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63692 GO:0048503 obsolete GPI anchor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048503 GPI anchor binding|glycosylphosphatidylinositol binding OBSOLETE. Interacting selectively with any glycosylphosphatidylinositol anchor. GPI anchors serve to attach membrane proteins to the lipid bilayer of cell membranes. GO:0048502 ABC-type thiamine transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048502 TC:3.A.1.19.1|EC:7.6.2.15|RHEA:29811 thiamine pyrophosphate-transporting ATPase activity|thiamine-transporting ATPase activity|TPP transporting ATPase activity|thiamine ABC transporter|thiamin pyrophosphate ABC transporter|thiamin-transporting ATPase activity|thiamin pyrophosphate porter activity|thiamin pyrophosphate transporting ATPase activity|ATP-dependent thiamine transmembrane transporter activity|ATPase-coupled thiamine transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + thiamine(out) = ADP + H(+) + phosphate + thiamine(in). CHEBI:63690 (1E,2Z)-3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63690 GO:0048501 signal recognition particle, plasma membrane targeting biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0048501 A complex consisting of a protein and RNA component which binds the signal sequence of some proteins and facilitates their export to or across the plasma membrane. GO:0048500 signal recognition particle biolink:CellularComponent go-plus goslim_metagenomics|goslim_pir http://purl.obolibrary.org/obo/GO_0048500 Wikipedia:Signal_recognition_particle A complex of protein and RNA which facilitates translocation of proteins across membranes. CHEBI:63696 gamma-curcumene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63696 CHEBI:63694 D-synephrine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63694 GO:0048509 regulation of meristem development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048509 Any process that modulates the frequency, rate or extent of meristem development, the biological process whose specific outcome is the progression of the meristem over time, from its formation to the mature structure. GO:0048508 embryonic meristem development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048508 The process whose specific outcome is the progression of the embryonic meristem over time, from its formation to the mature structure. GO:0048507 meristem development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048507 The process whose specific outcome is the progression of the meristem over time, from its formation to the mature structure. GO:0048506 regulation of timing of meristematic phase transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048506 Any process that modulates the rate, frequency or extent of a change in identity of a meristem at a characteristic predetermined time point. PO:0025417 xylem vessel biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025417 vaso xilem&$225tico (Spanish, exact)|木質部導管 (Japanese, exact)|vessel (exact) A portion of xylem (PO:0005352) tissue that has as parts a tube-like series of vessel members (PO:0002003), the common walls of which have perforations. PO:0025416 sieve tube biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025416 師(篩）管 (Japanese, exact)|tubo criboso (Spanish, exact) A portion of phloem tissue (PO:0005417) that has as parts a series of sieve tube elements (PO:0000289) arranged end to end and interconnected through sieve plates. PO:0025415 sieve cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025415 célula cribosa (Spanish, exact)|師（篩）細胞 (Japanese, exact) A sieve element (PO:0025406) in which the sieve areas are not aggregated into sieve plates (GO:0097218). CHEBI:73011 germacranolide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73011 GO:1903909 regulation of receptor clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903909 Any process that modulates the frequency, rate or extent of receptor clustering. GO:1903919 negative regulation of actin filament severing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903919 inhibition of actin filament severing activity|down regulation of actin filament severing|down-regulation of barbed-end actin capping/severing activity|negative regulation of F-actin severing|negative regulation of barbed-end actin capping/severing activity|down-regulation of F-actin severing|downregulation of actin filament severing|down-regulation of actin filament severing activity|downregulation of F-actin severing|downregulation of barbed-end actin capping/severing activity|negative regulation of actin filament severing activity|down-regulation of actin filament severing|down regulation of F-actin severing|down regulation of barbed-end actin capping/severing activity|inhibition of F-actin severing|inhibition of actin filament severing|downregulation of actin filament severing activity|inhibition of barbed-end actin capping/severing activity|down regulation of actin filament severing activity Any process that stops, prevents or reduces the frequency, rate or extent of actin filament severing. GO:1903918 regulation of actin filament severing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903918 regulation of F-actin severing|regulation of barbed-end actin capping/severing activity|regulation of actin filament severing activity Any process that modulates the frequency, rate or extent of actin filament severing. CHEBI:73026 2-methylbutyrylcarnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73026 GO:1903917 positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903917 up regulation of eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|up regulation of eIF2alpha dephosphorylation in response to ER stress|activation of eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|up regulation of regulation of translation initiation by eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|activation of regulation of translation initiation by eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|positive regulation of regulation of translation initiation by eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|upregulation of eIF2alpha dephosphorylation in response to ER stress|up-regulation of eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|activation of eIF2alpha dephosphorylation in response to ER stress|up-regulation of eIF2alpha dephosphorylation in response to ER stress|up-regulation of regulation of translation initiation by eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|upregulation of eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|positive regulation of eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|positive regulation of ER stress-induced eIF2 alpha dephosphorylation|upregulation of regulation of translation initiation by eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|positive regulation of eIF2alpha dephosphorylation in response to ER stress Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum stress-induced eIF2alpha dephosphorylation. CHEBI:73029 maackiain biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73029 GO:1903916 regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903916 regulation of regulation of translation initiation by eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|regulation of ER stress-induced eIF2 alpha dephosphorylation|regulation of eIF2alpha dephosphorylation in response to ER stress|regulation of eIF2alpha dephosphorylation in response to endoplasmic reticulum stress Any process that modulates the frequency, rate or extent of endoplasmic reticulum stress-induced eIF2alpha dephosphorylation. GO:1903915 positive regulation of fusion of virus membrane with host plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903915 activation of viral-cell fusion molecule activity|upregulation of fusion of virus membrane with host plasma membrane|upregulation of viral envelope fusion with host cell membrane|upregulation of viral envelope fusion with host plasma membrane|upregulation of viral envelope fusion with host membrane|up-regulation of viral entry into host cell via membrane fusion with the plasma membrane|up-regulation of viral-cell fusion molecule activity|up regulation of viral penetration via membrane fusion|up-regulation of fusion of virus membrane with host plasma membrane|activation of fusion of virus membrane with host plasma membrane|positive regulation of viral penetration via membrane fusion|activation of viral penetration via membrane fusion|up regulation of viral envelope fusion with host plasma membrane|up regulation of viral envelope fusion with host cell membrane|upregulation of viral entry into host cell via membrane fusion with the plasma membrane|up-regulation of viral envelope fusion with host membrane|positive regulation of viral envelope fusion with host cell membrane|activation of viral envelope fusion with host membrane|activation of viral envelope fusion with host cell membrane|positive regulation of viral envelope fusion with host plasma membrane|activation of viral envelope fusion with host plasma membrane|upregulation of viral-cell fusion molecule activity|up-regulation of viral penetration via membrane fusion|up regulation of viral entry into host cell via membrane fusion with the plasma membrane|up regulation of fusion of virus membrane with host plasma membrane|positive regulation of viral envelope fusion with host membrane|up-regulation of viral envelope fusion with host cell membrane|positive regulation of viral entry into host cell via membrane fusion with the plasma membrane|up-regulation of viral envelope fusion with host plasma membrane|up regulation of viral-cell fusion molecule activity|up regulation of viral envelope fusion with host membrane|positive regulation of viral-cell fusion molecule activity|activation of viral entry into host cell via membrane fusion with the plasma membrane|upregulation of viral penetration via membrane fusion Any process that activates or increases the frequency, rate or extent of fusion of virus membrane with host plasma membrane. GO:1903914 negative regulation of fusion of virus membrane with host plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903914 down regulation of viral envelope fusion with host membrane|down regulation of viral penetration via membrane fusion|inhibition of viral envelope fusion with host membrane|down regulation of viral envelope fusion with host cell membrane|down regulation of viral envelope fusion with host plasma membrane|downregulation of viral penetration via membrane fusion|downregulation of viral envelope fusion with host plasma membrane|downregulation of viral envelope fusion with host cell membrane|inhibition of viral entry into host cell via membrane fusion with the plasma membrane|inhibition of viral-cell fusion molecule activity|negative regulation of viral penetration via membrane fusion|down-regulation of viral penetration via membrane fusion|down regulation of viral entry into host cell via membrane fusion with the plasma membrane|down-regulation of fusion of virus membrane with host plasma membrane|down-regulation of viral envelope fusion with host cell membrane|negative regulation of viral envelope fusion with host plasma membrane|negative regulation of viral envelope fusion with host cell membrane|down-regulation of viral envelope fusion with host plasma membrane|down regulation of viral-cell fusion molecule activity|downregulation of viral entry into host cell via membrane fusion with the plasma membrane|down-regulation of viral envelope fusion with host membrane|negative regulation of viral envelope fusion with host membrane|inhibition of viral penetration via membrane fusion|downregulation of viral-cell fusion molecule activity|inhibition of viral envelope fusion with host cell membrane|inhibition of viral envelope fusion with host plasma membrane|downregulation of fusion of virus membrane with host plasma membrane|downregulation of viral envelope fusion with host membrane|negative regulation of viral entry into host cell via membrane fusion with the plasma membrane|down-regulation of viral entry into host cell via membrane fusion with the plasma membrane|down regulation of fusion of virus membrane with host plasma membrane|inhibition of fusion of virus membrane with host plasma membrane|negative regulation of viral-cell fusion molecule activity|down-regulation of viral-cell fusion molecule activity Any process that stops, prevents or reduces the frequency, rate or extent of fusion of virus membrane with host plasma membrane. GO:1903913 regulation of fusion of virus membrane with host plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903913 regulation of viral penetration via membrane fusion|regulation of viral envelope fusion|regulation of viral envelope fusion with host plasma membrane|regulation of viral envelope fusion with host cell membrane|regulation of viral entry into host cell via membrane fusion with the plasma membrane|regulation of viral-cell fusion molecule activity|regulation of viral envelope fusion with host membrane Any process that modulates the frequency, rate or extent of fusion of virus membrane with host plasma membrane. GO:1903912 negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903912 downregulation of regulation of translation initiation by eiF2alpha phosphorylation in response to endoplasmic reticulum stress|downregulation of eiF2alpha phosphorylation in response to ER stress|down-regulation of eiF2alpha phosphorylation in response to endoplasmic reticulum stress|down regulation of eiF2alpha phosphorylation in response to ER stress|inhibition of eiF2alpha phosphorylation in response to ER stress|inhibition of eiF2alpha phosphorylation in response to endoplasmic reticulum stress|negative regulation of regulation of translation initiation by eiF2alpha phosphorylation in response to endoplasmic reticulum stress|down-regulation of regulation of translation initiation by eiF2alpha phosphorylation in response to endoplasmic reticulum stress|inhibition of regulation of translation initiation by eiF2alpha phosphorylation in response to endoplasmic reticulum stress|negative regulation of eiF2alpha phosphorylation in response to endoplasmic reticulum stress|negative regulation of ER stress-induced eIF2 alpha phosphorylation|down regulation of eiF2alpha phosphorylation in response to endoplasmic reticulum stress|down-regulation of eiF2alpha phosphorylation in response to ER stress|negative regulation of eiF2alpha phosphorylation in response to ER stress|downregulation of eiF2alpha phosphorylation in response to endoplasmic reticulum stress|down regulation of regulation of translation initiation by eiF2alpha phosphorylation in response to endoplasmic reticulum stress Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum stress-induced eiF2alpha phosphorylation. GO:1903911 positive regulation of receptor clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903911 upregulation of receptor clustering|up regulation of receptor clustering|activation of receptor clustering|up-regulation of receptor clustering Any process that activates or increases the frequency, rate or extent of receptor clustering. GO:0048516 obsolete trichome initiation (sensu Magnoliophyta) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048516 trichome initiation (sensu Magnoliophyta) OBSOLETE. Processes causing the differentiation of an epidermal cell into a trichome cell; as in, but not restricted to, the flowering plants (Magnoliophyta, ncbi_taxonomy_id:3398). GO:1903910 negative regulation of receptor clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903910 down regulation of receptor clustering|downregulation of receptor clustering|down-regulation of receptor clustering|inhibition of receptor clustering Any process that stops, prevents or reduces the frequency, rate or extent of receptor clustering. GO:0048515 spermatid differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048515 spermatid cell differentiation The process whose specific outcome is the progression of a spermatid over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. GO:0048514 blood vessel morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048514 The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood. GO:0048513 animal organ development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048513 Wikipedia:Organogenesis organogenesis|development of an organ Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. GO:0048512 circadian behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048512 circadian rhythm behavior The specific behavior of an organism that recurs with a regularity of approximately 24 hours. CHEBI:87653 (25R)-3beta,26-dihydroxycholest-5-en-7-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87653 GO:0048511 rhythmic process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0048511 rhythm Any process pertinent to the generation and maintenance of rhythms in the physiology of an organism. GO:0048510 regulation of timing of transition from vegetative to reproductive phase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048510 The process controlling the point in time during development when a vegetative meristem will change its identity to become an inflorescence or floral meristem, and/or the rate at which the change occurs. CHEBI:87657 octanoate ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87657 CHEBI:87656 hexanoate ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87656 CHEBI:87659 dodecanoate ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87659 CHEBI:87658 decanoate ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87658 GO:0048519 negative regulation of biological process biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0048519 down-regulation of biological process|downregulation of biological process|negative regulation of physiological process|down regulation of biological process|inhibition of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. GO:0048518 positive regulation of biological process biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0048518 up-regulation of biological process|activation of biological process|up regulation of biological process|positive regulation of physiological process|upregulation of biological process|stimulation of biological process Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. GO:0048517 obsolete positive regulation of trichome initiation (sensu Magnoliophyta) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048517 positive regulation of trichome initiation (sensu Magnoliophyta) OBSOLETE. Any process that activates or increases the frequency, rate or extent of trichome initiation; as in, but not restricted to, the flowering plants (Magnoliophyta, ncbi_taxonomy_id:3398). PO:0025406 sieve element biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025406 elemento criboso (Spanish, exact)|師(篩）要素 (Japanese, exact) A native plant cell (PO:0025606) that is part of a portion of phloem tissue (PO:0005417), has sieve areas in its walls, and lacks a nucleus in its mature protoplast. CHEBI:73025 O-isovalerylcarnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73025 CHEBI:73024 O-acetylcarnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73024 GO:1903929 primary palate development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903929 palatum primarium development|primitive palate development|processus palatinus medianus development|primary palate process development The process whose specific outcome is the progression of a primary palate over time, from its formation to the mature structure. GO:1903928 cellular response to cyanide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903928 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyanide stimulus. GO:1903927 response to cyanide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903927 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyanide stimulus. CHEBI:73039 O-octanoylcarnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73039 GO:1903926 cellular response to bisphenol A biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903926 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bisphenol A stimulus. GO:1903925 response to bisphenol A biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903925 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bisphenol A stimulus. GO:1903924 estradiol binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1903924 Interacting selectively and non-covalently with estradiol. GO:1903923 positive regulation of protein processing in phagocytic vesicle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903923 up regulation of protein maturation by peptide bond hydrolysis in phagosome|up-regulation of protein maturation by peptide bond cleavage in phagocytic vesicle|upregulation of protein maturation by proteolysis in phagosome|up-regulation of protein maturation by peptide bond cleavage in phagosome|up regulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|up-regulation of protein maturation by proteolysis in phagocytic vesicle|activation of protein maturation by peptide bond cleavage in phagosome|activation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|positive regulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|up-regulation of protein processing in phagocytic vesicle|upregulation of peptidolysis during protein maturation in phagosome|activation of protein processing in phagocytic vesicle|upregulation of protein processing in phagosome|upregulation of peptidolysis during protein maturation in phagocytic vesicle|upregulation of protein maturation by peptide bond cleavage in phagocytic vesicle|up-regulation of protein maturation by proteolysis in phagosome|upregulation of protein maturation by peptide bond hydrolysis in phagosome|upregulation of protein maturation by proteolysis in phagocytic vesicle|positive regulation of protein maturation by peptide bond cleavage in phagosome|up regulation of peptidolysis during protein maturation in phagosome|up-regulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|up regulation of protein maturation by peptide bond cleavage in phagosome|activation of protein maturation by proteolysis in phagosome|positive regulation of peptidolysis during protein maturation in phagosome|up regulation of protein processing in phagosome|up-regulation of peptidolysis during protein maturation in phagocytic vesicle|up regulation of protein processing in phagocytic vesicle|positive regulation of protein processing in phagosome|activation of protein processing in phagosome|up regulation of protein maturation by peptide bond cleavage in phagocytic vesicle|up-regulation of protein maturation by peptide bond hydrolysis in phagosome|activation of protein maturation by peptide bond hydrolysis in phagosome|positive regulation of protein maturation by proteolysis in phagosome|up regulation of protein maturation by proteolysis in phagocytic vesicle|activation of protein maturation by peptide bond cleavage in phagocytic vesicle|activation of peptidolysis during protein maturation in phagosome|positive regulation of protein maturation by peptide bond cleavage in phagocytic vesicle|up regulation of protein maturation by proteolysis in phagosome|activation of peptidolysis during protein maturation in phagocytic vesicle|upregulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|positive regulation of protein maturation by proteolysis in phagocytic vesicle|upregulation of protein maturation by peptide bond cleavage in phagosome|up-regulation of peptidolysis during protein maturation in phagosome|upregulation of protein processing in phagocytic vesicle|positive regulation of peptidolysis during protein maturation in phagocytic vesicle|activation of protein maturation by proteolysis in phagocytic vesicle|up regulation of peptidolysis during protein maturation in phagocytic vesicle|up-regulation of protein processing in phagosome|positive regulation of protein maturation by peptide bond hydrolysis in phagosome Any process that activates or increases the frequency, rate or extent of protein processing in phagocytic vesicle. GO:0048527 lateral root development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048527 The process whose specific outcome is the progression of the lateral root over time, from its formation to the mature structure. A lateral root is one formed from pericycle cells located on the xylem radius of the root, as opposed to the initiation of the main root from the embryo proper. GO:1903922 negative regulation of protein processing in phagocytic vesicle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903922 inhibition of protein maturation by proteolysis in phagosome|downregulation of protein maturation by peptide bond hydrolysis in phagosome|down regulation of peptidolysis during protein maturation in phagocytic vesicle|down regulation of peptidolysis during protein maturation in phagosome|inhibition of protein maturation by proteolysis in phagocytic vesicle|down regulation of protein maturation by peptide bond hydrolysis in phagosome|down-regulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|negative regulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|inhibition of protein maturation by peptide bond hydrolysis in phagosome|negative regulation of protein maturation by peptide bond cleavage in phagosome|down-regulation of protein maturation by peptide bond cleavage in phagosome|down regulation of protein processing in phagosome|inhibition of peptidolysis during protein maturation in phagocytic vesicle|downregulation of peptidolysis during protein maturation in phagosome|down-regulation of protein processing in phagocytic vesicle|down regulation of protein maturation by peptide bond cleavage in phagocytic vesicle|downregulation of protein processing in phagosome|down regulation of protein maturation by proteolysis in phagocytic vesicle|inhibition of protein maturation by peptide bond hydrolysis in phagocytic vesicle|down-regulation of protein maturation by proteolysis in phagosome|negative regulation of protein maturation by proteolysis in phagosome|downregulation of protein maturation by peptide bond cleavage in phagocytic vesicle|downregulation of protein maturation by proteolysis in phagocytic vesicle|downregulation of protein maturation by peptide bond cleavage in phagosome|negative regulation of peptidolysis during protein maturation in phagosome|down-regulation of peptidolysis during protein maturation in phagosome|downregulation of protein processing in phagocytic vesicle|down regulation of protein maturation by peptide bond cleavage in phagosome|down-regulation of peptidolysis during protein maturation in phagocytic vesicle|inhibition of protein maturation by peptide bond cleavage in phagosome|down-regulation of protein processing in phagosome|negative regulation of peptidolysis during protein maturation in phagocytic vesicle|negative regulation of protein processing in phagosome|downregulation of protein maturation by proteolysis in phagosome|down regulation of protein processing in phagocytic vesicle|negative regulation of protein maturation by peptide bond cleavage in phagocytic vesicle|inhibition of protein processing in phagocytic vesicle|down-regulation of protein maturation by peptide bond cleavage in phagocytic vesicle|negative regulation of protein maturation by proteolysis in phagocytic vesicle|down-regulation of protein maturation by proteolysis in phagocytic vesicle|down regulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|down-regulation of protein maturation by peptide bond hydrolysis in phagosome|negative regulation of protein maturation by peptide bond hydrolysis in phagosome|down regulation of protein maturation by proteolysis in phagosome|inhibition of protein processing in phagosome|downregulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|inhibition of peptidolysis during protein maturation in phagosome|downregulation of peptidolysis during protein maturation in phagocytic vesicle|inhibition of protein maturation by peptide bond cleavage in phagocytic vesicle Any process that stops, prevents or reduces the frequency, rate or extent of protein processing in phagocytic vesicle. GO:1903921 regulation of protein processing in phagocytic vesicle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903921 regulation of peptidolysis during protein maturation in phagocytic vesicle|regulation of protein maturation by peptide bond hydrolysis in phagosome|regulation of peptidolysis during protein maturation in phagosome|regulation of protein processing in phagosome|regulation of protein maturation by peptide bond cleavage in phagocytic vesicle|regulation of protein maturation by proteolysis in phagocytic vesicle|regulation of protein maturation by peptide bond cleavage in phagosome|regulation of protein maturation by proteolysis in phagosome|regulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle Any process that modulates the frequency, rate or extent of protein processing in phagocytic vesicle. GO:0048526 imaginal disc-derived wing expansion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048526 wing inflation|wing expansion The process of expanding or inflating the folded imaginal disc-derived pupal wing, and the adhering of the dorsal and ventral surfaces, to form the mature adult wing. GO:1903920 positive regulation of actin filament severing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903920 up regulation of actin filament severing activity|upregulation of barbed-end actin capping/severing activity|upregulation of F-actin severing|up-regulation of actin filament severing|activation of F-actin severing|upregulation of actin filament severing activity|up-regulation of F-actin severing|up-regulation of barbed-end actin capping/severing activity|upregulation of actin filament severing|activation of barbed-end actin capping/severing activity|up-regulation of actin filament severing activity|positive regulation of F-actin severing|positive regulation of barbed-end actin capping/severing activity|up regulation of actin filament severing|up regulation of barbed-end actin capping/severing activity|up regulation of F-actin severing|activation of actin filament severing|activation of actin filament severing activity|positive regulation of actin filament severing activity Any process that activates or increases the frequency, rate or extent of actin filament severing. GO:0048525 negative regulation of viral process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048525 negative regulation of viral reproduction|negative regulation of viral life cycle|down-regulation of viral life cycle|downregulation of viral life cycle|down regulation of viral life cycle|inhibition of viral life cycle Any process that stops, prevents, or reduces the frequency, rate or extent of a multi-organism process in which a virus is a participant. GO:0048524 positive regulation of viral process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048524 up-regulation of viral life cycle|stimulation of viral life cycle|positive regulation of viral reproduction|positive regulation of viral life cycle|activation of viral life cycle|up regulation of viral life cycle|upregulation of viral life cycle Any process that activates or increases the frequency, rate or extent of a multi-organism process in which a virus is a participant. GO:0048523 negative regulation of cellular process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048523 down-regulation of cellular process|downregulation of cellular process|down regulation of cellular process|inhibition of cellular process|negative regulation of cellular physiological process Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. GO:0048522 positive regulation of cellular process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048522 stimulation of cellular process|activation of cellular process|up-regulation of cellular process|up regulation of cellular process|upregulation of cellular process|positive regulation of cellular physiological process Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. CHEBI:14737 pantoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_14737 GO:0048521 negative regulation of behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048521 inhibition of behavior|down-regulation of behavior|downregulation of behavior|down regulation of behavior Any process that stops, prevents, or reduces the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli. GO:0048520 positive regulation of behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048520 upregulation of behavior|stimulation of behavior|up-regulation of behavior|activation of behavior|up regulation of behavior Any process that activates or increases the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli. CHEBI:87687 (3S)-3-hydroxyoleoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87687 GO:0048529 magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048529 EC:1.14.13.81|RHEA:33235 Mg-protoporphyrin IX monomethyl ester oxidative cyclase activity|magnesium-protoporphyrin-IX 13-monomethyl ester,NADPH:oxygen oxidoreductase (hydroxylating)|Mg-protoporphyrin IX monomethyl ester (oxidative) cyclase activity Catalysis of the reaction: magnesium protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 H+ + 3 O2 = divinylprotochlorophyllide + 3 NADP+ + 5 H2O. GO:0048528 post-embryonic root development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048528 The process whose specific outcome is the progression of the post-embryonic root over time, from its formation to the mature structure. PR:000001887 melanotransferrin biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001887 MELTF|membrane-bound transferrin-like protein p97|MTf|MFI2|CD228|MAP97|melanoma-associated antigen p97 A protein that is a translation product of the human MELTF gene or a 1:1 ortholog thereof. CHEBI:73030 (+)-maackiain biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73030 CHEBI:73036 4-hydroxy-2-oxoheptanedioate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73036 GO:0048530 fruit morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048530 The process in which the anatomical structures of a fruit are generated and organized. A fruit is a reproductive body of a seed plant. GO:1903939 regulation of TORC2 signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903939 regulation of TORC2 signal transduction Any process that modulates the frequency, rate or extent of TORC2 signaling. PR:000025848 type I interferon biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000025848 interferon type I|IFN type I A protein that consists solely of an Interferon alpha/beta domain (Pfam:PF00143) and which binds to a specific cell surface receptor complex known as the IFN-alpha receptor (IFNAR), a heterodimer of IFNAR1 and IFNAR2 chains. GO:1903938 cellular response to acrylamide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903938 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acrylamide stimulus. GO:1903937 response to acrylamide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903937 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acrylamide stimulus. GO:1903936 cellular response to sodium arsenite biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903936 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium arsenite stimulus. GO:1903935 response to sodium arsenite biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903935 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium arsenite stimulus. PR:000025845 ephrin receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000025845 A protein that consists of an Ephrin receptor ligand binding domain (Pfam:PF01404), two copies of the Fibronectin type III domain (Pfam:PF00041), and a copy of either type of SAM domain (Sterile alpha motif) (Pfam:PF00536 or Pfam:PF07647). GO:1903934 positive regulation of DNA primase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903934 upregulation of DNA primase activity|activation of DNA primase activity|up-regulation of DNA primase activity|up regulation of DNA primase activity Any process that activates or increases the frequency, rate or extent of DNA primase activity. GO:1903933 negative regulation of DNA primase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903933 downregulation of DNA primase activity|down regulation of DNA primase activity|inhibition of DNA primase activity|down-regulation of DNA primase activity Any process that stops, prevents or reduces the frequency, rate or extent of DNA primase activity. GO:0048538 thymus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048538 The process whose specific outcome is the progression of the thymus over time, from its formation to the mature structure. The thymus is a symmetric bi-lobed organ involved primarily in the differentiation of immature to mature T cells, with unique vascular, nervous, epithelial, and lymphoid cell components. GO:1903932 regulation of DNA primase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903932 Any process that modulates the frequency, rate or extent of DNA primase activity. GO:0048537 mucosa-associated lymphoid tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048537 nasopharyngeal-associated lymphoid tissue development|BALT development|bronchial-associated lymphoid tissue development|GALT development|gut-associated lymphoid tissue development|NALT development|mucosal-associated lymphoid tissue development The process whose specific outcome is the progression of mucosal-associated lymphoid tissue over time, from its formation to the mature structure. Mucosal-associated lymphoid tissue is typically found as nodules associated with mucosal epithelia with distinct internal structures including B- and T-zones for the activation of lymphocytes. GO:1903931 positive regulation of pyrimidine-containing compound salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903931 up-regulation of pyrimidine salvage|upregulation of pyrimidine-containing compound salvage|activation of pyrimidine salvage|up-regulation of pyrimidine-containing compound salvage|positive regulation of pyrimidine salvage|activation of pyrimidine-containing compound salvage|up regulation of pyrimidine salvage|upregulation of pyrimidine salvage|up regulation of pyrimidine-containing compound salvage Any process that activates or increases the frequency, rate or extent of pyrimidine-containing compound salvage. GO:0048536 spleen development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048536 The process whose specific outcome is the progression of the spleen over time, from its formation to the mature structure. The spleen is a large vascular lymphatic organ composed of white and red pulp, involved both in hemopoietic and immune system functions. CHEBI:87673 2-O-(alpha-D-mannopyranosyl)-1-phosphatidyl-1D-myo-inositol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87673 GO:1903930 regulation of pyrimidine-containing compound salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903930 regulation of pyrimidine salvage Any process that modulates the frequency, rate or extent of pyrimidine-containing compound salvage. GO:0048535 lymph node development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048535 lymph gland development The process whose specific outcome is the progression of lymph nodes over time, from their formation to the mature structure. A lymph node is a round, oval, or bean shaped structure localized in clusters along the lymphatic vessels, with a distinct internal structure including specialized vasculature and B- and T-zones for the activation of lymphocytes. GO:0048534 hematopoietic or lymphoid organ development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048534 hemopoietic or lymphoid organ development|haemopoietic or lymphoid organ development|haematopoietic or lymphoid organ development The process whose specific outcome is the progression of any organ involved in hematopoiesis (also known as hemopoiesis) or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation. GO:0048533 sporocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048533 sporocyte development|sporocyte morphogenesis The process in which a relatively unspecialized floral cell acquires the specialized features of a sporocyte. Sporocytes are the haploid spores of angiosperms. Once formed, they undergo meiotic divisions to form microspores and megaspores. GO:0048532 anatomical structure arrangement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048532 organization of an anatomical structure|anatomical structure structural organization|structural organization|anatomical structure organization The process that gives rise to the configuration of the constituent parts of an anatomical structure. This process pertains to the physical shaping of a rudimentary structure. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. CHEBI:87677 (25R)-3beta-hydroxycholest-5-en-7-one-26-al biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87677 GO:0048531 beta-1,3-galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0048531 Catalysis of the transfer of a galactose residue from a donor molecule to an oligosaccharide, forming a beta-1,3-linkage. CHEBI:87678 (25R)-3beta-hydroxycholest-5-en-7-one-26-oate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87678 GO:0048539 bone marrow development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048539 The process whose specific outcome is the progression of the bone marrow over time, from its formation to the mature structure. GO:0048541 Peyer's patch development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048541 GALT development|gut-associated lymphoid tissue development The process whose specific outcome is the progression of Peyer's patches over time, from their formation to the mature structure. Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes. GO:0048540 bursa of Fabricius development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048540 The process whose specific outcome is the progression of the bursa of Fabricius over time, from its formation to the mature structure. The bursa of Fabricius is an organ found in birds involved in B cell differentiation. GO:1903949 positive regulation of atrial cardiac muscle cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903949 up-regulation of atrial cardiac muscle cell action potential|upregulation of atrial cardiac muscle cell action potential|up regulation of atrial cardiac muscle cell action potential|activation of atrial cardiac muscle cell action potential Any process that activates or increases the frequency, rate or extent of atrial cardiac muscle cell action potential. GO:1903948 negative regulation of atrial cardiac muscle cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903948 inhibition of atrial cardiac muscle cell action potential|down regulation of atrial cardiac muscle cell action potential|downregulation of atrial cardiac muscle cell action potential|down-regulation of atrial cardiac muscle cell action potential Any process that stops, prevents or reduces the frequency, rate or extent of atrial cardiac muscle cell action potential. GO:1903947 positive regulation of ventricular cardiac muscle cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903947 up-regulation of ventricular cardiac muscle cell action potential|activation of ventricular cardiac muscle cell action potential|up regulation of ventricular cardiac muscle cell action potential|upregulation of ventricular cardiac muscle cell action potential Any process that activates or increases the frequency, rate or extent of ventricular cardiac muscle cell action potential. GO:1903946 negative regulation of ventricular cardiac muscle cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903946 down-regulation of ventricular cardiac muscle cell action potential|downregulation of ventricular cardiac muscle cell action potential|down regulation of ventricular cardiac muscle cell action potential|inhibition of ventricular cardiac muscle cell action potential Any process that stops, prevents or reduces the frequency, rate or extent of ventricular cardiac muscle cell action potential. GO:1903945 positive regulation of hepatocyte apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903945 up-regulation of hepatocyte apoptosis|up-regulation of hepatocyte apoptotic process|activation of hepatocyte apoptosis|activation of hepatocyte apoptotic process|positive regulation of hepatocyte apoptosis|up regulation of hepatocyte apoptosis|up regulation of hepatocyte apoptotic process|upregulation of hepatocyte apoptosis|upregulation of hepatocyte apoptotic process Any process that activates or increases the frequency, rate or extent of hepatocyte apoptotic process. GO:1903944 negative regulation of hepatocyte apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903944 down-regulation of hepatocyte apoptosis|negative regulation of hepatocyte apoptosis|down-regulation of hepatocyte apoptotic process|downregulation of hepatocyte apoptosis|down regulation of hepatocyte apoptosis|downregulation of hepatocyte apoptotic process|down regulation of hepatocyte apoptotic process|inhibition of hepatocyte apoptosis|inhibition of hepatocyte apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte apoptotic process. GO:0048549 positive regulation of pinocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048549 up regulation of pinocytosis|activation of pinocytosis|stimulation of pinocytosis|up-regulation of pinocytosis|upregulation of pinocytosis Any process that activates, maintains or increases the rate of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes. GO:0048548 regulation of pinocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048548 Any process that modulates the frequency, rate or extent of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes. GO:1903943 regulation of hepatocyte apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903943 regulation of hepatocyte apoptosis Any process that modulates the frequency, rate or extent of hepatocyte apoptotic process. GO:1903942 positive regulation of respiratory gaseous exchange biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903942 upregulation of respiratory gaseous exchange|up-regulation of respiratory gaseous exchange|activation of respiratory gaseous exchange|up regulation of respiratory gaseous exchange Any process that activates or increases the frequency, rate or extent of respiratory gaseous exchange. GO:0048547 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048547 GO:1903941 negative regulation of respiratory gaseous exchange biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903941 downregulation of respiratory gaseous exchange|down regulation of respiratory gaseous exchange|inhibition of respiratory gaseous exchange|down-regulation of respiratory gaseous exchange Any process that stops, prevents or reduces the frequency, rate or extent of respiratory gaseous exchange. GO:0048546 digestive tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048546 gastrointestinal tract morphogenesis|gut morphogenesis|digestive tube morphogenesis|intestinal morphogenesis|alimentary canal morphogenesis The process in which the anatomical structures of the digestive tract are generated and organized. The digestive tract is the anatomical structure through which food passes and is processed. GO:1903940 negative regulation of TORC2 signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903940 downregulation of TORC2 signaling|down regulation of TORC2 signal transduction|downregulation of TORC2 signal transduction|down-regulation of TORC2 signaling|negative regulation of TORC2 signal transduction|down-regulation of TORC2 signal transduction|inhibition of TORC2 signaling|inhibition of TORC2 signal transduction|down regulation of TORC2 signaling Any process that stops, prevents or reduces the frequency, rate or extent of TORC2 signaling. GO:0048545 response to steroid hormone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048545 response to steroid hormone stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus. GO:0048544 recognition of pollen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048544 pollen recognition|self incompatibility|recognition or rejection of self pollen The process, involving the sharing and interaction of the single locus incompatibility haplotypes, involved in the recognition or rejection of the self pollen by cells in the stigma. This process ensures out-breeding in certain plant species. GO:0048543 phytochrome chromophore biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048543 phytochrome chromophore anabolism|phytochrome chromophore biosynthesis|phytochrome chromophore synthesis|phytochrome chromophore formation The chemical reactions and pathways resulting in the formation of the phytochrome chromophore. The phytochrome chromophore is a linear tetrapyrrolic prosthetic group covalently attached to the large soluble protein phytochrome. Light absorption by the phytochrome chromophore triggers photoconversion between two spectrally distinct forms of the photoreceptor: Pr, the red light absorbing form, and Pfr, the far red light absorbing form. GO:0048542 lymph gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048542 haematopoietic organ development|hemopoietic organ development|hematopoietic organ development|haemopoietic organ development The process whose specific outcome is the progression of the lymph gland over time, from its formation to the mature structure. The lymph gland is one of the sites of hemocyte differentiation. It consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages. CHEBI:73054 O-dodecanoylcarnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73054 GO:0048552 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048552 GO:0048551 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048551 GO:0048550 negative regulation of pinocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048550 down regulation of pinocytosis|downregulation of pinocytosis|down-regulation of pinocytosis|inhibition of pinocytosis Any process that stops, prevents, or reduces the frequency, rate or extent of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes. PO:0025450 primary xylem vessel biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025450 vaso del xilema primario (Spanish, exact)|一次木質部導管 (Japanese, exact) A xylem vessel (PO:0025417) that is part of a primary xylem tissue (PO:0005849). GO:1903959 regulation of anion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903959 Any process that modulates the frequency, rate or extent of anion transmembrane transport. GO:1903958 nitric-oxide synthase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1903958 iNOS-S100A8/A9 complex A protein complex which is capable of nitric-oxide synthase activity. GO:1903957 cellular response to latrunculin B biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903957 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a latrunculin B stimulus. CHEBI:87691 tetradecanoate ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87691 GO:1903956 response to latrunculin B biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903956 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a latrunculin B stimulus. GO:1903955 positive regulation of protein targeting to mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903955 up regulation of protein-mitochondrial targeting|activation of protein-mitochondrial targeting|positive regulation of protein-mitochondrial targeting|up-regulation of protein import into mitochondrion|up-regulation of mitochondrial protein import|upregulation of mitochondrial translocation|up-regulation of protein targeting to mitochondria|upregulation of protein targeting to mitochondrion|activation of mitochondrial protein import|upregulation of protein import into mitochondrion|up-regulation of protein-mitochondrial targeting|positive regulation of mitochondrial protein import|upregulation of protein targeting to mitochondria|up regulation of mitochondrial translocation|up-regulation of protein targeting to mitochondrion|activation of protein targeting to mitochondrion|up regulation of mitochondrial protein import|positive regulation of mitochondrial translocation|up regulation of protein import into mitochondrion|activation of mitochondrial translocation|upregulation of protein-mitochondrial targeting|activation of protein import into mitochondrion|positive regulation of protein import into mitochondrion|up regulation of protein targeting to mitochondria|activation of protein targeting to mitochondria|positive regulation of protein targeting to mitochondria|upregulation of mitochondrial protein import|up-regulation of mitochondrial translocation|up regulation of protein targeting to mitochondrion Any process that activates or increases the frequency, rate or extent of protein targeting to mitochondrion. GO:1903954 positive regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903954 up-regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization|upregulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|upregulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization|up regulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|activation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|positive regulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|up regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization|activation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization|up-regulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization Any process that activates or increases the frequency, rate or extent of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization. GO:0048559 establishment of floral organ orientation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048559 The process that determines the orientation of the floral organs with reference to the central axis of the flower. GO:1903953 negative regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903953 inhibition of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization|down regulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|downregulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|down regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization|downregulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization|down-regulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|negative regulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|inhibition of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|down-regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization. GO:0048558 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048558 CHEBI:87695 3-oxooleoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87695 GO:0048557 embryonic digestive tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048557 embryonic gut morphogenesis The process in which the anatomical structures of the digestive tract are generated and organized during embryonic development. The digestive tract is the anatomical structure through which food passes and is processed. GO:1903952 regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903952 regulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization Any process that modulates the frequency, rate or extent of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization. GO:0048556 microsporocyte nucleus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0048556 pollen mother cell nucleus|microspore mother cell nucleus The nucleus of the microsporocyte. The microsporocyte is a diploid cell in which meiosis will occur, resulting in four microspores. A microspore is a spore that, in vascular plants, gives rise to a male gametophyte. GO:1903951 positive regulation of AV node cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903951 positive regulation of atrioventricular node cardiac muscle cell action potential|up-regulation of AV node cell action potential|up regulation of atrioventricular node cardiac muscle cell action potential|positive regulation of AV node cardiac muscle cell action potential|up regulation of AV node cardiac muscle cell action potential|upregulation of AV node cell action potential|upregulation of atrioventricular node cardiac muscle cell action potential|upregulation of AV node cardiac muscle cell action potential|up regulation of AV node cell action potential|activation of AV node cell action potential|up-regulation of atrioventricular node cardiac muscle cell action potential|activation of atrioventricular node cardiac muscle cell action potential|up-regulation of AV node cardiac muscle cell action potential|activation of AV node cardiac muscle cell action potential Any process that activates or increases the frequency, rate or extent of AV node cell action potential. GO:1903950 negative regulation of AV node cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903950 inhibition of AV node cell action potential|negative regulation of AV node cardiac muscle cell action potential|down-regulation of AV node cardiac muscle cell action potential|downregulation of atrioventricular node cardiac muscle cell action potential|down regulation of atrioventricular node cardiac muscle cell action potential|downregulation of AV node cardiac muscle cell action potential|inhibition of atrioventricular node cardiac muscle cell action potential|down regulation of AV node cell action potential|down regulation of AV node cardiac muscle cell action potential|inhibition of AV node cardiac muscle cell action potential|downregulation of AV node cell action potential|down-regulation of AV node cell action potential|negative regulation of atrioventricular node cardiac muscle cell action potential|down-regulation of atrioventricular node cardiac muscle cell action potential Any process that stops, prevents or reduces the frequency, rate or extent of AV node cell action potential. GO:0048555 generative cell nucleus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0048555 sperm cell nucleus|male germ cell nucleus The nucleus of the generative cell, a cell contained within the pollen grain that will divide to produce two haploid sperm cells. GO:0048554 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048554 GO:0048553 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048553 CHEBI:87698 (7Z)-hexadecenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87698 CL:1001451 sensory neuron of dorsal root ganglion biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001451 proprioceptive neuron A sensory neuron of the dorsal root ganglia that senses body position and sends information about how much the muscle is stretched to the spinal cord. CHEBI:73061 O-tetradecanoylcarnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73061 PO:0025448 primary xylem vessel member biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025448 primary xylem vessel element (exact)|elemento vaso del xilema primario (Spanish, exact)|一次木質部導管状要素 (Japanese, exact) A xylem vessel member (PO:0002003) that is part of a primary xylem tissue (PO:0005849). CHEBI:73067 O-palmitoylcarnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73067 GO:0048563 post-embryonic animal organ morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048563 Morphogenesis, during the post-embryonic phase, of an animal tissue or tissues that work together to perform a specific function or functions. Morphogenesis pertains to process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. CHEBI:143285 L-propargylglycine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_143285 GO:0048562 embryonic organ morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048562 Morphogenesis, during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. GO:0048561 establishment of animal organ orientation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048561 The process that determines the orientation of an animal organ or tissue with reference to an axis. GO:0048560 establishment of anatomical structure orientation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048560 The process that determines the orientation of an anatomical structure with reference to an axis. GO:1903969 regulation of response to macrophage colony-stimulating factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903969 regulation of response to macrophage colony-stimulating factor|regulation of response to M-CSF|regulation of response to macrophage colony-stimulating factor stimulus Any process that modulates the frequency, rate or extent of response to macrophage colony-stimulating factor. GO:1903968 cellular response to micafungin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903968 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a micafungin stimulus. GO:1903967 response to micafungin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903967 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a micafungin stimulus. GO:1903966 monounsaturated fatty acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903966 monounsaturated fatty acid biosynthesis|monounsaturated fatty acid anabolism|monounsaturated fatty acid synthesis|monounsaturated fatty acid formation The chemical reactions and pathways resulting in the formation of monounsaturated fatty acid. GO:1903965 monounsaturated fatty acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903965 monounsaturated fatty acid catabolism|monounsaturated fatty acid breakdown|monounsaturated fatty acid degradation The chemical reactions and pathways resulting in the breakdown of monounsaturated fatty acid. GO:0048569 post-embryonic animal organ development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048569 post-embryonic animal organogenesis Development, taking place during the post-embryonic phase of an animal tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. GO:1903964 monounsaturated fatty acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903964 monounsaturated fatty acid metabolism The chemical reactions and pathways involving monounsaturated fatty acid. GO:1903963 arachidonate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903963 arachidonic acid transport The directed movement of an arachidonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0048568 embryonic organ development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048568 embryonic organogenesis Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. GO:1903962 arachidonate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1903962 arachidonate transporter activity|arachidonic acid transporter activity Enables the transfer of arachidonate from one side of a membrane to the other. GO:0048567 ectodermal digestive tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048567 ectodermal gut morphogenesis The process in which the anatomical structures of the ectodermal digestive tract are generated and organized. The ectodermal digestive tract includes those portions of the digestive tract that are derived from ectoderm. GO:0048566 embryonic digestive tract development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048566 embryonic digestive tract development The process whose specific outcome is the progression of the gut over time, from its formation to the mature structure during embryonic development. The gut is the region of the digestive tract extending from the beginning of the intestines to the anus. GO:1903961 positive regulation of anion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903961 up regulation of anion transmembrane transport|activation of anion transmembrane transport|up-regulation of anion transmembrane transport|upregulation of anion transmembrane transport Any process that activates or increases the frequency, rate or extent of anion transmembrane transport. GO:1903960 negative regulation of anion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903960 down-regulation of anion transmembrane transport|inhibition of anion transmembrane transport|down regulation of anion transmembrane transport|downregulation of anion transmembrane transport Any process that stops, prevents or reduces the frequency, rate or extent of anion transmembrane transport. GO:0048565 digestive tract development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048565 gut development|intestine development|intestinal development The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed. GO:0048564 photosystem I assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048564 The aggregation, arrangement and bonding together of a set of components to form a photosystem I complex on the thylakoid membrane. CHEBI:73078 3''-deamino-3''-hydroxykanamycin C biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73078 PO:0025433 root anlagen biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025433 precursor de raí (Spanish, exact)|根原基 (Japanese, exact) A portion of meristem tissue (PO:0009013) that is committed to the development of a root primordium (PO:0005029). PO:0025432 cotyledon anlagen biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025432 precursor de cotiledón (Spanish, exact)|子葉原基 (Japanese, exact) A phyllome anlagen (PO:0025430) that will give rise to a cotyledon primordium (PO:0000015) and is part of a peripheral zone (PO:000225) of an embryo shoot apical meristem (PO:0006362). CHEBI:73079 kanamycin D biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73079 GO:0048574 long-day photoperiodism, flowering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048574 long-day photoperiodic control of flowering|long-day photoperiodic control of flowering time|response to long-day, flowering|response to short-night, flowering|long-day photoperiodic control of inflorescence development|short-night photoperiodism, flowering A change from the vegetative to the reproductive phase as a result of detection of, or exposure to, a period of light that exceeds the critical day length. The critical day length varies between species. Although the term is long-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness falls short of the number of hours defined by 24 minus the critical day length. PO:0025431 vascular leaf anlagen biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025431 leaf meristem (broad)|維管束系葉原基 (Japanese, exact) A phyllome anlagen (PO:0025430) that will give rise to a vascular leaf primordium (PO:0000017) and is part of a peripheral zone (PO:0000225) of a shoot apical meristem (PO:0020148). CHEBI:143274 indole-3-butyrate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_143274 GO:0048573 photoperiodism, flowering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048573 response to photoperiod, flowering|response to day length, flowering|response to night length, flowering|photoperiodic control of inflorescence development|photoperiodic control of flowering time A change from the vegetative to the reproductive phase as a result of detection of, or exposure to, a period of light or dark of a given length. The length of the period of light or dark required to initiate the change is set relative to a particular duration known as the 'critical day length'. The critical day length varies between species. PO:0025430 phyllome anlagen biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025430 phyllome meristem (broad)|フィロム原基 (Japanese, exact) A portion of meristem tissue (PO:0009013) that is part of a peripheral zone (PO:0000225) of a shoot apical meristem (PO:0020148) and will give rise to a phyllome primordium (PO:0025128). GO:0048572 short-day photoperiodism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048572 response to short-day|response to short-day photoperiod|response to long-night|long-night photoperiodism Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a day length that falls short of a particular duration known as the 'critical day length'. The critical day length varies between species. Although the term short-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness exceeds the number of hours defined by 24 hours minus the critical day length. GO:0048571 long-day photoperiodism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048571 response to short-night|response to long-day photoperiod|response to long-day|short-night photoperiodism Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a day length that exceeds a particular duration known as the 'critical day length'. The critical day length varies between species. Although the term long-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness falls short of the number of hours defined by 24 hours minus the critical day length. GO:0048570 notochord morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048570 The process in which the anatomical structures of the notochord are generated and organized. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column. GO:1903979 negative regulation of microglial cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903979 downregulation of microglial cell activation|down regulation of microglial cell activation|inhibition of microglial cell activation|down-regulation of microglial cell activation Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell activation. GO:1903978 regulation of microglial cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903978 Any process that modulates the frequency, rate or extent of microglial cell activation. GO:1903977 positive regulation of glial cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903977 up regulation of glial cell migration|activation of glia cell migration|positive regulation of glia cell migration|upregulation of glial cell migration|up-regulation of glia cell migration|up-regulation of glial cell migration|upregulation of glia cell migration|activation of glial cell migration|up regulation of glia cell migration Any process that activates or increases the frequency, rate or extent of glial cell migration. GO:1903976 negative regulation of glial cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903976 downregulation of glial cell migration|negative regulation of glia cell migration|down-regulation of glia cell migration|down regulation of glial cell migration|inhibition of glial cell migration|inhibition of glia cell migration|down regulation of glia cell migration|down-regulation of glial cell migration|downregulation of glia cell migration Any process that stops, prevents or reduces the frequency, rate or extent of glial cell migration. GO:1903975 regulation of glial cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903975 regulation of glia cell migration Any process that modulates the frequency, rate or extent of glial cell migration. GO:1903974 positive regulation of cellular response to macrophage colony-stimulating factor stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903974 up-regulation of cellular response to macrophage colony-stimulating factor stimulus|activation of cellular response to macrophage colony-stimulating factor stimulus|upregulation of cellular response to macrophage colony-stimulating factor|upregulation of cellular response to M-CSF stimulus|up regulation of cellular response to macrophage colony-stimulating factor|positive regulation of cellular response to macrophage colony-stimulating factor|up regulation of cellular response to macrophage colony-stimulating factor stimulus|activation of cellular response to macrophage colony-stimulating factor|up regulation of cellular response to M-CSF stimulus|positive regulation of cellular response to M-CSF stimulus|activation of cellular response to M-CSF stimulus|upregulation of cellular response to macrophage colony-stimulating factor stimulus|up-regulation of cellular response to macrophage colony-stimulating factor|up-regulation of cellular response to M-CSF stimulus Any process that activates or increases the frequency, rate or extent of cellular response to macrophage colony-stimulating factor stimulus. GO:0048579 negative regulation of long-day photoperiodism, flowering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048579 downregulation of long-day photoperiodism, flowering|down regulation of long-day photoperiodism, flowering|inhibition of long-day photoperiodism, flowering|down-regulation of long-day photoperiodism, flowering Any process that stops, prevents or reduces long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase. GO:1903973 negative regulation of cellular response to macrophage colony-stimulating factor stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903973 down regulation of cellular response to macrophage colony-stimulating factor|down-regulation of cellular response to macrophage colony-stimulating factor stimulus|downregulation of cellular response to macrophage colony-stimulating factor|down regulation of cellular response to M-CSF stimulus|downregulation of cellular response to M-CSF stimulus|downregulation of cellular response to macrophage colony-stimulating factor stimulus|down-regulation of cellular response to macrophage colony-stimulating factor|negative regulation of cellular response to macrophage colony-stimulating factor|down regulation of cellular response to macrophage colony-stimulating factor stimulus|inhibition of cellular response to macrophage colony-stimulating factor stimulus|negative regulation of cellular response to M-CSF stimulus|down-regulation of cellular response to M-CSF stimulus|inhibition of cellular response to macrophage colony-stimulating factor|inhibition of cellular response to M-CSF stimulus Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to macrophage colony-stimulating factor stimulus. GO:0048578 positive regulation of long-day photoperiodism, flowering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048578 up regulation of long-day photoperiodism, flowering|upregulation of long-day photoperiodism, flowering|stimulation of long-day photoperiodism, flowering|up-regulation of long-day photoperiodism, flowering|activation of long-day photoperiodism, flowering Any process that activates, maintains or increases long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase. GO:0048577 negative regulation of short-day photoperiodism, flowering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048577 inhibition of short-day photoperiodism, flowering|down regulation of short-day photoperiodism, flowering|downregulation of short-day photoperiodism, flowering|down-regulation of short-day photoperiodism, flowering Any process that stops, prevents or reduces short-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase. GO:1903972 regulation of cellular response to macrophage colony-stimulating factor stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903972 regulation of cellular response to macrophage colony-stimulating factor|regulation of cellular response to M-CSF stimulus Any process that modulates the frequency, rate or extent of cellular response to macrophage colony-stimulating factor stimulus. GO:1903971 positive regulation of response to macrophage colony-stimulating factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903971 up regulation of response to M-CSF|activation of response to M-CSF|positive regulation of response to M-CSF|up-regulation of response to macrophage colony-stimulating factor|activation of response to macrophage colony-stimulating factor|up regulation of response to macrophage colony-stimulating factor stimulus|activation of response to macrophage colony-stimulating factor stimulus|positive regulation of response to macrophage colony-stimulating factor stimulus|up-regulation of response to M-CSF|positive regulation of response to macrophage colony-stimulating factor|up regulation of response to macrophage colony-stimulating factor|up-regulation of response to macrophage colony-stimulating factor stimulus|upregulation of response to M-CSF|upregulation of response to macrophage colony-stimulating factor|upregulation of response to macrophage colony-stimulating factor stimulus Any process that activates or increases the frequency, rate or extent of response to macrophage colony-stimulating factor. GO:0048576 positive regulation of short-day photoperiodism, flowering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048576 up-regulation of short-day photoperiodism, flowering|upregulation of short-day photoperiodism, flowering|up regulation of short-day photoperiodism, flowering|activation of short-day photoperiodism, flowering|stimulation of short-day photoperiodism, flowering Any process that activates, maintains or increases short-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase. GO:0048575 short-day photoperiodism, flowering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048575 short-day photoperiodic control of flowering|response to long-night, flowering|short-day photoperiodic control of flowering time|short-day photoperiodic control of inflorescence development|response to short-day, flowering|long-night photoperiodism, flowering A change from vegetative to reproductive phase as a result of detection of, or exposure to, a period of light that falls short of the critical day length. The critical day length varies between species. Although the term is short-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness exceeds the number of hours defined by 24 minus the critical day length. GO:1903970 negative regulation of response to macrophage colony-stimulating factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903970 downregulation of response to macrophage colony-stimulating factor stimulus|down-regulation of response to M-CSF|negative regulation of response to M-CSF|negative regulation of response to macrophage colony-stimulating factor|down-regulation of response to macrophage colony-stimulating factor|down-regulation of response to macrophage colony-stimulating factor stimulus|negative regulation of response to macrophage colony-stimulating factor stimulus|inhibition of response to M-CSF|downregulation of response to macrophage colony-stimulating factor|inhibition of response to macrophage colony-stimulating factor stimulus|down regulation of response to macrophage colony-stimulating factor|inhibition of response to macrophage colony-stimulating factor|down regulation of response to M-CSF|downregulation of response to M-CSF|down regulation of response to macrophage colony-stimulating factor stimulus Any process that stops, prevents or reduces the frequency, rate or extent of response to macrophage colony-stimulating factor. GO:1903980 positive regulation of microglial cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903980 up-regulation of microglial cell activation|activation of microglial cell activation|up regulation of microglial cell activation|upregulation of microglial cell activation Any process that activates or increases the frequency, rate or extent of microglial cell activation. CL:1001474 medium spiny neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001474 medium-sized densely spiny neuron|striatal medium spiny neuron The inhibitory projection neurons located in the striatum that integrate glutamatergic signals arising from the cerebral cortex and thalamus. CHEBI:73081 O-(15-carboxypentadecanoyl)carnitine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73081 CHEBI:73080 hemiaminal biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73080 CHEBI:73083 (7,8-dihydropterin-6-yl)methyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73083 CHEBI:73084 N-[(7,8-dihydropterin-6-yl)methyl]-4-(beta-D-ribofuranosyl)aniline 5'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73084 CHEBI:73087 dihydrourocanic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73087 CHEBI:73089 4-hydroxy-2-oxoheptanedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73089 CHEBI:24002 ethylene releasers biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24002 UBERON:0001668 cerebellar vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001668 epencephalon-1 vein|vein of cerebellum|cerebellum vein|vein of epencephalon-1 A vein that drains the cerebellum. GO:0000721 (R,R)-butanediol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000721 RHEA:24340|EC:1.1.1.4|MetaCyc:RR-BUTANEDIOL-DEHYDROGENASE-RXN D-1-amino-2-propanol:NAD(2) oxidoreductase activity|aminopropanol oxidoreductase activity|(R)-2,3-butanediol dehydrogenase activity|D-1-amino-2-propanol dehydrogenase activity|D-butanediol dehydrogenase activity|D-aminopropanol dehydrogenase activity|(R)-diacetyl reductase activity|diacetyl (acetoin) reductase activity|butylene glycol dehydrogenase activity|D-(-)-butanediol dehydrogenase activity|2,3-butanediol dehydrogenase activity|1-amino-2-propanol oxidoreductase activity|1-amino-2-propanol dehydrogenase activity|butyleneglycol dehydrogenase activity Catalysis of the reversible reaction: (R,R)-butane-2,3-diol + NAD+ = (R)-acetoin + NADH + H(+). GO:0000720 pyrimidine dimer repair by nucleotide-excision repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000720 The repair of UV-induced T-T, C-T, and C-C dimers by the recognition and removal of the damaged DNA strand from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. NCBITaxon:2759 Eukaryota organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_2759 eukaryotes|eukaryotes|Eucaryotae|Eukaryotae|Eukarya|eucaryotes|Eucarya CHEBI:38646 O-beta-D-glucosylzeatin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38646 CHEBI:38645 N-glycosylzeatin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38645 CHEBI:38644 O-beta-D-glucosylzeatins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38644 CHEBI:38643 6-isopentenylaminopurine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38643 UBERON:0001675 trigeminal ganglion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001675 trigeminal V ganglion|fused trigeminal ganglion|trigeminus ganglion|trigeminal ganglia|Gasserian ganglion|Gasserian ganglia|ganglion trigeminale|ganglion of trigeminal complex|Gasser's ganglion|fifth ganglion|ganglion of trigeminal nerve|gV|ganglion semilunare|semilunar ganglion|5th ganglion The cranial ganglion that is associated with and extends fibers into the trigeminal nerve. GO:0000725 recombinational repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000725 Wikipedia:Recombinational_repair A DNA repair process that involves the exchange, reciprocal or nonreciprocal, of genetic material between the broken DNA molecule and a homologous region of DNA. GO:0000724 double-strand break repair via homologous recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000724 homologous recombinational repair|homology-directed repair|HDR|HRR|Rad51-dependent recombinational repair|Rhp51-dependent recombinational repair The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule. UBERON:0001677 sphenoid bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001677 os sphenoidum|os sphenoidale|sphenoidal bone|sphenoid complex|sphenoid|butterfly bone|os sphenoidale An unpaired bone situated at the base of the skull in front of the temporal bone and basilar part of the occipital bone. The sphenoid bone is one of the seven bones that articulate to form the orbit. Its shape somewhat resembles that of a butterfly or bat with its wings extended. GO:0000723 telomere maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000723 regulation of telomere length Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins, the length of telomeric DNA and the replication and repair of the DNA. These processes includes those that shorten, lengthen, replicate and repair the telomeric DNA sequences. CHEBI:63618 pravastatin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63618 GO:0000722 telomere maintenance via recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000722 telomerase-independent telomere maintenance Any recombinational process that contributes to the maintenance of proper telomeric length. UBERON:0001676 occipital bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001676 occipital complex|os occipitale|occipital squama the bone at the lower, posterior part of the skull GO:0000729 DNA double-strand break processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000729 The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang. GO:0000728 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000728 GO:0000727 double-strand break repair via break-induced replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000727 The error-free repair of a double-strand break in DNA in which the centromere-proximal end of a broken chromosome searches for a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template, and progresses to the end of the chromosome. GO:0000726 non-recombinational repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000726 A DNA repair process in which that does not require the exchange of genetic material between the broken DNA molecule and a homologous region of DNA. GO:0000732 strand displacement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000732 displacement loop dissociation|D-loop dissociation|displacement loop processing|D-loop processing The rejection of the broken 3' single-strand DNA molecule that formed heteroduplex DNA with its complement in an intact duplex DNA. The Watson-Crick base pairing in the original duplex is restored. The rejected 3' single-strand DNA molecule reanneals with its original complement to reform two intact duplex molecules. GO:0000731 DNA synthesis involved in DNA repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000731 DNA repair synthesis|mitotic DNA repair synthesis|DNA synthesis during DNA repair Synthesis of DNA that proceeds from the broken 3' single-strand DNA end and uses the homologous intact duplex as the template. GO:0000730 DNA recombinase assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000730 Rad51 nucleoprotein filament formation The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) into higher order oligomers on single-stranded DNA. CHEBI:24018 farnesyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24018 CHEBI:133901 3-aminobutyryl-CoA(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133901 CHEBI:133900 14(R),15(S)-DiHPETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133900 CHEBI:133903 8(S),15(S)-DiHETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133903 CHEBI:133902 dUMP residue(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133902 CHEBI:24012 farnesal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_24012 CHEBI:63624 telbivudine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63624 CHEBI:38656 organochlorine pesticide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38656 CHEBI:38655 (S)-2-methylbutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38655 GO:0000736 double-strand break repair via single-strand annealing, removal of nonhomologous ends biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000736 During DSBR via single-strand annealing, the removal of nonhomologous sequences at the broken 3' single-strand DNA end before DNA repair synthesis can occur. UBERON:0001663 cerebral vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001663 venae cerebri|venae encephali The cerebral veins are divisible into external and internal groups according to the outer surfaces or the inner parts of the hemispheres they drain into. The external veins are the superior cerebral veins, inferior cerebral veins, and middle cerebral vein. [WP,unvetted]. GO:0000735 removal of nonhomologous ends biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000735 The removal of nonhomologous sequences at the broken 3' single-strand DNA end before DNA repair synthesis can occur. GO:0000734 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000734 GO:0000733 DNA strand renaturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000733 The identification and annealing of complementary base pairs in single-strand DNA. CHEBI:38653 methylbutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38653 GO:0000739 obsolete DNA strand annealing activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000739 DNA strand annealing activity OBSOLETE. Facilitates the base-pairing of complementary single-stranded DNA. GO:0000738 DNA catabolic process, exonucleolytic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000738 exonucleolytic degradation of DNA|DNA degradation, exonucleolytic|DNA breakdown, exonucleolytic The chemical reactions and pathways resulting in the breakdown of DNA, involving the hydrolysis of terminal 3',5'-phosphodiester bonds in one or two strands of deoxyribonucleotides. GO:0000737 DNA catabolic process, endonucleolytic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000737 endonucleolytic DNA catabolism|DNA degradation, endonucleolytic|endonucleolytic degradation of DNA|DNA breakdown, endonucleolytic The chemical reactions and pathways resulting in the breakdown of DNA, involving the hydrolysis of internal 3',5'-phosphodiester bonds in one or two strands of deoxyribonucleotides. UBERON:0001649 glossopharyngeal nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001649 nervus glossopharyngeus [ix]|glossopharyngeal IX nerve|CN-IX|9n|ninth cranial nerve|glossopharyngeal nerve tree|cranial nerve IX|nervus glossopharyngeus|glossopharyngeal IX|nervus glossopharyngeus|nerve IX|glossopharyngeal nerve [IX] Cranial nerve that branches into the ramus communicans (to the skin), the pretrematic (to the walls of the pharynx and mouth, viscero-sensory fibers), and the larval post-trematic branch (lost in the adult). UBERON:0001646 abducens nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001646 nervus abducens|abducens nerve tree|sixth cranial nerve|lateral rectus nerve|CN-VI|nervus abducens [VI]|6n|cranial nerve VI|abducens nerve [VI]|abducent nerve [VI]|abducens nerve/root|abducens VI nerve|nerve VI|nervus abducens|abducent nerve|abducents VI nerve Cranial nerve that runs to the eye muscles. UBERON:0001645 trigeminal nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001645 fifth cranial nerve|trigeminal v nerve|cranial nerve V|nervus trigeminus [v]|CN-V|5n|nervus trigeminus|trigeminal V|nervus trigeminus|trigeminus|trigeminal nerve [V]|trigeminal nerve tree|nerve V Cranial nerve that has three branches - the ophthalmic (supplying the skin of the nose and upper jaw), the maxillary and the mandibular (supplying the lower jaw). UBERON:0001648 vestibulocochlear nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001648 eighth cranial nerve|vestibulocochlear nerve [VIII]|acoustic VIII nerve|CN-VIII|vestibulocochlear VIII nerve|nervus statoacusticus|cranial nerve VIII|cochlear-vestibular nerve|acoustic nerve|8n|vestibulocochlear nerve tree|acoustic nerve (Crosby)|VIIIth cranial nerve|nervus vestibulocochlearis|nervus octavus|octaval nerve|statoacoustic nerve|nervus vestibulocochlearis [viii]|cochleovestibular nerve|stato-acoustic nerve|VIII nerve Cranial nerve that transmits sound and equilibrium (balance) information from the inner ear to the brain. UBERON:0001647 facial nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001647 nerve VII|nervus facialis|facial nerve [VII]|facial nerve/root|cranial nerve VII|nerve of face|CN-VII|branchiomeric cranial nerve|7n|facial VII nerve|facial nerve or its root|facial nerve tree|face nerve|seventh cranial nerve|facial VII|nervus facialis [vii]|nervus facialis Cranial nerve that branches into the supraorbital (supplying the skin of the eye region and the lateral line organs here), the palatine (to the roof of the buccal cavity), and the hyomandibular (dividing into the jugular and mental branches). CL:1001569 hippocampal interneuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001569 An interneuron of the hippocampus. CL:1001568 pulmonary artery endothelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001568 PAEC cell CL:1001567 lung endothelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001567 pulmonary vessel endothelial cell|endothelial cell of lung CHEBI:87602 4-hydroxyestrone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87602 CHEBI:38623 EC 1.4.3.4 (monoamine oxidase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38623 GO:0000709 meiotic joint molecule formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000709 The conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination. These joint molecules contain Holliday junctions on either side of heteroduplex DNA. GO:0000708 meiotic strand invasion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000708 meiotic displacement loop biosynthesis|meiotic displacement loop formation|meiotic D-loop biosynthesis|meiotic D-loop formation The cell cycle process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules. This occurs during meiosis. CHEBI:87606 N-icosanoylglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87606 CHEBI:87605 6alpha-hydroxyestrone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87605 UBERON:0001653 facial vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001653 vena facialis anterior|anterior facial vein|vein of face|face vein The anterior facial vein (facial vein) commences at the side of the root of the nose, and is a direct continuation of the angular vein where it also receives a small nasal branch. It lies behind the facial artery and follows a less tortuous course. It receives blood from the external palatine vein before it either joins the anterior branch of the retromandibular vein to form the common facial vein, or drains directly into the internal jugular vein. [WP,unvetted]. GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000703 Reactome:R-HSA-110224|Reactome:R-HSA-110226|Reactome:R-HSA-110227 endonuclease III|DNA glycosylase/beta-lyase|endonuclease VIII activity|DNA glycosylase/AP-lyase|oxidized pyrimidine base lesion DNA N-glycosylase activity|bifunctional DNA glycosylase|endodeoxyribonuclease III|pyrimidine-specific oxidized base lesion DNA N-glycosylase activity Catalysis of the removal oxidized pyrimidine bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar. The reaction involves formation of a covalent enzyme-pyrimidine base intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apyrimidinic (AP) site. GO:0000702 oxidized base lesion DNA N-glycosylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000702 Catalysis of the removal of oxidized bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site. UBERON:0001652 left pulmonary artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001652 left pulmonary arterial tree|left main pulmonary artery|arteria pulmonalis sinistra The pulmonary artery that supplies the left lung. GO:0000701 purine-specific mismatch base pair DNA N-glycosylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000701 EC:3.2.2.- A/G-specific adenine DNA glycosylase activity Catalysis of the removal of purines present in mismatches, especially opposite oxidized purines, by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic (AP) site. GO:0000700 mismatch base pair DNA N-glycosylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000700 Catalysis of the removal of single bases present in mismatches by the cleavage the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site. GO:0000707 meiotic DNA recombinase assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000707 During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA. GO:0000706 meiotic DNA double-strand break processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000706 The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang occurs. This takes place during meiosis. GO:0000705 achiasmate meiosis I biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000705 achiasmate meiosis I nuclear division The first division of meiosis in which homologous chromosomes are paired and segregated from each other, occurring in the constitutive absence of chiasmata. UBERON:0001651 right pulmonary artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001651 right pulmonary arterial tree|arteria pulmonalis dextra|right main pulmonary artery The pulmonary artery that supplies the right lung. UBERON:0001650 hypoglossal nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001650 12n|hypoglossal nerve/ root|nerve XII|hypoglossal XII|cranial nerve XII|nervi hypoglossalis|twelfth cranial nerve|CN-XII|nervus hypoglossus [xii]|hypoglossal nerve tree|hypoglossal nerve [XII]|nervus hypoglossus|hypoglossal XII nerve Cranial nerve that innervates the muscles of the tongue. GO:0000704 pyrimidine dimer DNA N-glycosylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000704 Catalysis of the removal of pyrimidine dimers by removing the 5' pyrimidine of the dimer by cleaving the N-C1' glycosidic bond between the 5' pyrimidine of the dimer and the deoxyribose sugar. The reaction releases the 5' pyrimidine of the dimer and leaves an apurinic (AP) site. The reaction involves the formation of a covalent enzyme substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apyrimidinic (AP) site. UBERON:0001638 vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001638 venous subtree|venae|vena|venous vessel|vascular element|venous tree organ part Any of the tubular branching vessels that carry blood from the capillaries toward the heart. GO:0000710 meiotic mismatch repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000710 A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules. Correction of the mismatch can result in non-Mendelian segregation of alleles following meiosis. UBERON:0001637 artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001637 arterial vessel|arterial tree organ part|arteries|arterial system|arterial subtree An epithelial tube or tree of tibes that transports blood away from the heart[modified from AEO definition]. CHEBI:63641 9alpha-hydroxyandrosta-1,4-diene-3,17-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63641 CHEBI:63640 26-hydroxycholest-4-en-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63640 CHEBI:38633 sodium channel blocker biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38633 CHEBI:63644 9-hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63644 GO:0000719 photoreactive repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000719 pyrimidine-dimer repair by photolyase The repair of UV-induced T-T, C-T and C-C dimers by directly reversing the damage to restore the original pyrimidines. CHEBI:38632 membrane transport modulator biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38632 CHEBI:38637 tyrosine kinase inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38637 GO:0000714 meiotic strand displacement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000714 meiotic displacement loop processing|meiotic D-loop processing|meiotic displacement loop dissociation|meiotic D-loop dissociation The cell cycle process in which the broken 3' single-strand DNA molecule that formed heteroduplex DNA with its complement in an intact duplex DNA is rejected. The Watson-Crick base pairing in the original duplex is restored. The rejected 3' single-strand DNA molecule reanneals with its original complement to reform two intact duplex molecules. This occurs during meiosis. GO:0000713 meiotic heteroduplex formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000713 During meiosis, the formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules. UBERON:0001644 trochlear nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001644 trochlear IV nerve|trochlear nerve tree|pathetic nerve|nervus trochlearis [IV]|4n|superior oblique nerve|trochlear nerve [IV]|cranial nerve IV|CN-IV|trochlear nerve/root|nervus trochlearis|nerve IV|fourth cranial nerve|trochlear nerve or its root|trochlear A cranial nerve that runs to the eye muscles. GO:0000712 resolution of meiotic recombination intermediates biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000712 resolution of meiotic joint molecules as recombinants The cleavage and rejoining of intermediates, such as Holliday junctions, formed during meiotic recombination to produce two intact molecules in which genetic material has been exchanged. UBERON:0001643 oculomotor nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001643 nervus oculomotorius|3n|nerve III|oculomotor nerve or its root|oculomotor nerve [III]|third cranial nerve|occulomotor|cranial nerve III|oculomotor III nerve|oculomotor nerve tree|CN-III|nervus oculomotorius [III]|oculomotor III Cranial nerve which connects the midbrain to the extra-ocular and intra-ocular muscles. GO:0000711 meiotic DNA repair synthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000711 During meiosis, the synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template. GO:0000718 nucleotide-excision repair, DNA damage removal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000718 The removal of the oligonucleotide that contains the DNA damage. The oligonucleotide is formed by dual incisions that flank the site of DNA damage. CHEBI:38631 aminoalkylindole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38631 GO:0000717 nucleotide-excision repair, DNA duplex unwinding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000717 The unwinding, or local denaturation, of the DNA duplex to create a bubble around the site of the DNA damage. UBERON:0001640 celiac artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001640 arteria cœliaca|coeliac artery|celiac trunk|coeliac trunk|coeliac axis|coeliac trunck|truncus cœliacus|celiac tree|arteria coeliaca|truncus coeliacus The first major branch of the abdominal aorta. GO:0000716 transcription-coupled nucleotide-excision repair, DNA damage recognition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000716 pyrimidine-dimer repair, DNA damage recognition The identification of lesions on the actively transcribed strand of the DNA duplex as well as a small subset of lesions not recognized by the general nucleotide-excision repair pathway. GO:0000715 nucleotide-excision repair, DNA damage recognition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000715 pyrimidine-dimer repair, DNA damage recognition The identification of lesions in DNA, such as pyrimidine-dimers, intrastrand cross-links, and bulky adducts. The wide range of substrate specificity suggests the repair complex recognizes distortions in the DNA helix. CL:1001509 glycinergic neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001509 The neurons that utilize glycine as a neurotransmitter. GO:0048703 embryonic viscerocranium morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048703 embryonic pharyngeal skeleton morphogenesis The process in which the anatomical structures of the viscerocranium are generated and organized during the embryonic phase. The viscerocranium is the part of the skull comprising the facial bones. GO:0048702 embryonic neurocranium morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048702 embryonic chondrocranium morphogenesis|embryonic braincase morphogenesis The process in which the anatomical structures of the neurocranium are generated and organized during the embryonic phase. The neurocranium is the portion of the vertebrate skull surrounding the brain. CHEBI:38609 indolecarboxylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38609 GO:0048701 embryonic cranial skeleton morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048701 embryonic cranium morphogenesis The process in which the anatomical structures of the cranial skeleton are generated and organized during the embryonic phase. CHEBI:38608 dibenzazecine alkaloid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38608 GO:0048700 acquisition of desiccation tolerance in seed biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048700 acquisition of desiccation tolerance The process in which a seed acquires tolerance to severe drying, before entering into a dry, either dormant or quiescent state. CHEBI:38607 dibenzazecine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38607 CHEBI:87620 16beta-hydroxyestradiol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87620 CL:1001503 olfactory bulb tufted cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001503 The principal glutaminergic neuron located in the outer third of the external plexiform layer of the olfactory bulb; a single short primary dendrite traverses the outer external plexiform layer and terminates within an olfactory glomerulus in a tuft of branches, where it receives the input from olfactory receptor neuron axon terminals; axons of the tufted cells transfer information to a number of areas in the brain, including the piriform cortex, entorhinal cortex, olfactory tubercle, and amygdala. CHEBI:63656 9beta-pimara-7,15-dien-19-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63656 CHEBI:87623 methanediimine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87623 GO:0048709 oligodendrocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048709 The process in which a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system. CHEBI:38600 4H-pyrazol-4-ide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38600 CHEBI:87626 6beta-hydroxyestrone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87626 CHEBI:63655 (3R,5R)-7-[(1S,2S,6S,8S,8aR)-6,8-dihydroxy-2-methyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63655 GO:0048708 astrocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048708 The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function. GO:0048707 instar larval or pupal morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048707 The process, occurring during instar larval or pupal development, by which anatomical structures are generated and organized. CHEBI:38606 cyclopentapyran biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38606 GO:0048706 embryonic skeletal system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048706 embryonic skeletal development The process, occurring during the embryonic phase, whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. CHEBI:38605 phenethylamine alkaloid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38605 GO:0048705 skeletal system morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048705 skeletal morphogenesis The process in which the anatomical structures of the skeleton are generated and organized. CHEBI:63659 9beta-pimara-7,15-dien-19-oate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63659 GO:0048704 embryonic skeletal system morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048704 embryonic skeletal morphogenesis The process in which the anatomical structures of the skeleton are generated and organized during the embryonic phase. CHEBI:63658 9beta-pimara-7,15-dien-19-al biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63658 GO:0048714 positive regulation of oligodendrocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048714 up regulation of oligodendrocyte differentiation|activation of oligodendrocyte differentiation|stimulation of oligodendrocyte differentiation|up-regulation of oligodendrocyte differentiation|upregulation of oligodendrocyte differentiation Any process that activates or increases the frequency, rate or extent of oligodendrocyte differentiation. CHEBI:63660 pravastatin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63660 GO:0048713 regulation of oligodendrocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048713 Any process that modulates the frequency, rate or extent of oligodendrocyte differentiation. GO:0048712 negative regulation of astrocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048712 down regulation of astrocyte differentiation|downregulation of astrocyte differentiation|down-regulation of astrocyte differentiation|inhibition of astrocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of astrocyte differentiation. GO:0048711 positive regulation of astrocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048711 upregulation of astrocyte differentiation|up regulation of astrocyte differentiation|activation of astrocyte differentiation|stimulation of astrocyte differentiation|up-regulation of astrocyte differentiation Any process that activates or increases the frequency, rate or extent of astrocyte differentiation. GO:0048710 regulation of astrocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048710 Any process that modulates the frequency, rate or extent of astrocyte differentiation. CHEBI:63664 taxusin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63664 CHEBI:63663 10beta,14beta-dihydroxytaxa-4(20),11-dien-5alpha-yl acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63663 CHEBI:63662 11alpha-hydroxy-ent-cassa-12,15-diene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63662 CHEBI:63668 abieta-7,13-dien-18,18-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63668 CHEBI:63665 7beta-hydroxytaxusin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63665 GO:0048719 epistomal sclerite morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048719 The process in which the anatomical structures of the epistomal sclerite are generated and organized. GO:0048718 cibarial fish-trap bristle morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048718 fish trap bristle morphogenesis The process in which the anatomical structures of a cibarial fish-trap bristle are generated and organized. A cibarial fish-trap bristle is a sensory bristle on the anterior plate of the cibarium. GO:0048717 anterior cibarial plate morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048717 The process in which the anatomical structures of the anterior cibarial plate are generated and organized. GO:0048716 labrum morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048716 The process in which the anatomical structures of labrum are generated and organized. CHEBI:38615 cyclopiazonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38615 GO:0048715 negative regulation of oligodendrocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048715 downregulation of oligodendrocyte differentiation|down-regulation of oligodendrocyte differentiation|inhibition of oligodendrocyte differentiation|down regulation of oligodendrocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of oligodendrocyte differentiation. CHEBI:87618 15alpha-hydroxyestrone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87618 GO:0048725 cibarial fish-trap bristle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048725 fish-trap bristle development The process whose specific outcome is the progression of the cibarial fish-trap bristle over time, from its formation to the mature structure. A cibarial fish-trap bristle is a sensory bristle on the anterior plate of the cibarium. CHEBI:63671 TRIBOA beta-D-glucoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63671 GO:0048724 epistomal sclerite development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048724 The process whose specific outcome is the progression of the epistomal sclerite over time, from its formation to the mature structure. CHEBI:63670 DIBOA beta-D-glucoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63670 GO:0048723 clypeus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048723 The process whose specific outcome is the progression of the clypeus over time, from its formation to the mature structure. The clypeus is the shield-shaped plate on an insect's head. GO:0048722 anterior cibarial plate development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048722 The process whose specific outcome is the progression of the anterior cibarial plate over time, from their formation to the mature structure. GO:0048721 clypeus morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048721 The process in which the anatomical structures of the clypeus are generated and organized. GO:0048720 posterior cibarial plate morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048720 The process in which the anatomical structures of the posterior cibarial plate are generated and organized. CHEBI:63672 3-methoxy-4',5-dihydroxy-trans-stilbene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63672 CHEBI:63679 [4)-beta-D-GlcA-(1->4)-beta-D-GlcA2(or 3)Ac-(1->4)-beta-D-Glc-(1->4)-[(R)-4,6-CH3(COO(-))C-beta-D-Gal3(or 2)OHb-(1->3)-(S)-4,6-CH3(COO(-))C-beta-D-Glc-(1->4)-beta-D-Glc-(1->4)-beta-D-Glc-(1->6)]-alpha-DGlc2(or 3)Ac-(1->]n biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63679 PR:000011407 mineralocorticoid receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000011407 MR|NR3C2|nuclear receptor subfamily 3 group C member 2|MCR|MLR A protein that is a translation product of the human NR3C2 gene or a 1:1 ortholog thereof. UBERON:0001691 external ear biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001691 auricular region of head|outer ear|auricular region|auris externa Part of the ear external to the tympanum (eardrum). It typically consists of a tube (the external auditory meatus) that directs sound waves on to the tympanum, and may also include the external pinna, which extends beyond the skull[GO]. PR:000011406 glucocorticoid receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000011406 GR|NR3C1|GRL|nuclear receptor subfamily 3 group C member 1|Grl1 A protein that is a translation product of the human NR3C1 gene or a 1:1 ortholog thereof. CHEBI:63677 erythromycin D(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63677 CHEBI:63676 dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactopyranose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63676 UBERON:0001690 ear biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001690 auditory apparatus|auris Sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals. GO:0048729 tissue morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048729 The process in which the anatomical structures of a tissue are generated and organized. GO:0048728 proboscis development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048728 The process whose specific outcome is the progression of the proboscis over time, from its formation to the mature structure. GO:0048727 posterior cibarial plate development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048727 The process whose specific outcome is the progression of the posterior cibarial plate over time, from its formation to the mature structure. GO:0048726 labrum development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048726 The process whose specific outcome is the progression of the labrum over time, from its formation to the mature structure. UBERON:0001697 orbit of skull biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001697 eye socket|bony orbit|orbit of skull|orbit Subdivision of skeleton that is an anterolateral part of the cranium and structurally supports the eye. Includes bones formed and located in sclerotic layer of eyeball. CL:0001071 group 3 innate lymphoid cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001071 ILC3 An innate lymphoid cell that constituitively expresses RORgt and is capable of expressing IL17A and/or IL-22. UBERON:0001694 petrous part of temporal bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001694 petromastoid part of temporal bone|pars petrosa (os temporale)|petrosal bone|pars petrosa ossis temporalis|temporal bone petrous part|petrosal|petrous bone The petrous portion of the temporal bone or pyramid is pyramidal and is wedged in at the base of the skull between the sphenoid and occipital bones. Directed medially, forward, and a little upward, it presents for examination a base, an apex, three surfaces, and three angles, and contains, in its interior, the essential parts of the organ of hearing. The petrous portion is among the most basal elements of the skull and forms part of the endocranium.[WP,unvetted]. CHEBI:73005 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73005 CHEBI:73004 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73004 CHEBI:73007 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73007 CHEBI:73006 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73006 CHEBI:73009 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-icosatetraenoyl)-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73009 UBERON:0001679 ethmoid bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001679 ethmoidal bone|os ethmoidale|ethmoid A bone in the skull that separates the nasal cavity from the brain. As such, it is located at the roof of the nose, between the two orbits. The cubical bone is lightweight due to a spongy construction. The ethmoid bone is one of the bones that makes up the orbit of the eye[WP] UBERON:0001678 temporal bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001678 os temporale the large, irregular bone located at the base and side of the skull; consists of three parts at birth: squamous, tympanic, and petrous CHEBI:73008 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73008 GO:0048736 appendage development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048736 The process whose specific outcome is the progression of an appendage over time, from its formation to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch. CHEBI:63682 (5S,9S,10S,13E)-labda-7,13-dien-15-yl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63682 GO:0048735 haltere morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048735 The process in which the anatomical structures of a haltere are generated and organized. GO:0048734 proboscis morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048734 The process in which the anatomical structures of the proboscis are generated and organized. The proboscis is the trunk-like extension of the mouthparts on the adult head. CHEBI:63680 CMP-pseudaminate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63680 GO:0048733 sebaceous gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048733 The process whose specific outcome is the progression of the sebaceous gland over time, from its formation to the mature structure. GO:0048732 gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048732 The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion. CHEBI:87631 statin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87631 GO:0048731 system development biolink:BiologicalProcess go-plus goslim_mouse http://purl.obolibrary.org/obo/GO_0048731 The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process. UBERON:0011004 pharyngeal arch cartilage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011004 splanchnocranium cartilage|pharyngeal arch cartilages A cartilage element that is part of a splanchnocranium. CHEBI:14649 NMN(-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_14649 GO:0048730 epidermis morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048730 hypodermis morphogenesis The process in which the anatomical structures of the epidermis are generated and organized. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species. CHEBI:87633 statin (semi-synthetic) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87633 CHEBI:87632 statin (naturally occurring) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87632 CHEBI:63683 (13E)-labda-7,13-dien-15-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63683 CHEBI:63689 P(1),P(6)-bis(5'-adenosyl)hexaphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63689 CHEBI:14648 NMN(+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_14648 GO:0048739 cardiac muscle fiber development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048739 heart muscle fiber development|cardiac muscle fibre development The process whose specific outcome is the progression of cardiac muscle fiber over time, from its formation to the mature structure. GO:0048738 cardiac muscle tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048738 heart muscle development The process whose specific outcome is the progression of cardiac muscle over time, from its formation to the mature structure. GO:0048737 imaginal disc-derived appendage development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048737 The process whose specific outcome is the progression of an appendage over time, from its formation in the imaginal disc to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism. UBERON:0001686 auditory ossicle bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001686 ear ossicle|ossicular chain|middle ear ossicle|auditory bone|ear bone|ossicle of ear|ossicle of inner ear|auditory ossicle|ossicle|ear ossicles|middle ear bone One of 3 small bones contained within the middle ear space and serve to transmit sounds from the air to the fluid-filled labyrinth. The absence of the auditory ossicles would constitute a moderate-to-severe hearing loss. The term 'ossicles' literally means 'tiny bones' and commonly refers to the auditory ossicles, though the term may refer to any small bone throughout the body. [WP,unvetted]. UBERON:0001685 hyoid bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001685 hyoid bone|hyoideum|os hyoideum|lingual bone|hyoid A horseshoe shaped bone situated in the anterior midline of the neck between the chin and the thyroid cartilage. The hyoid bone provides attachment to the muscles of the floor of the mouth and the tongue above, the larynx below, and the epiglottis and pharynx behind. [WP,modified]. CL:0001082 immature innate lymphoid cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0001082 immature ILC An innate lyphoid cell with an immature phenotype. CHEBI:73001 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73001 UBERON:0001682 palatine bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001682 os palatinum|dermopalatine|palate bone|palatum|palatine A paired dermal bone situated in the mid-palate[Palaeos]. UBERON:0001681 nasal bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001681 os nasale|adnasal@fr|nasals|nasal@fr|nasal bones One of two small oblong bones, varying in size and form in different individuals; they are placed side by side at the middle and upper part of the face, and form, by their junction, 'the bridge' of the nose[WP]. Paired dermal bones, likened to a bone tube, positioned lateral to the supraethmoid. Nasal bones are transversed by the anterior most part of the supraorbital canals and bear one neuromast foramen in zebrafish[ZFA]. CHEBI:73000 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73000 CHEBI:73003 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73003 CHEBI:73002 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73002 GO:0010128 benzoate catabolic process via CoA ligation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010128 MetaCyc:PWY-283 anaerobic benzoate catabolism|anaerobic benzoate degradation|anaerobic benzoate breakdown|anaerobic benzoate catabolic process The chemical reactions and pathways resulting in the breakdown of benzoate, by its ligation to Coenzyme A to form benzoyl-CoA, which is then broken by an aerobic or anaerobic pathway. CHEBI:48052 2,3-dihydrodipicolinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48052 GO:0009139 pyrimidine nucleoside diphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009139 pyrimidine nucleoside diphosphate biosynthesis|pyrimidine nucleoside diphosphate anabolism|pyrimidine nucleoside diphosphate synthesis|pyrimidine nucleoside diphosphate formation The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar. CHEBI:24085 formimidoyltetrahydrofolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24085 GO:0010127 mycothiol-dependent detoxification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010127 MetaCyc:PWY1G-1|MetaCyc:PWY1G-170 mycothiol-dependent detoxification of alkylating agent The chemical reactions using mycothiol to convert an alkylating agent to an S-conjugate of mycothiol. The latter is cleaved to release mercapturic acid which is excreted from the cell. CHEBI:133977 S-(2,4-dinitrophenyl)glutathione(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133977 GO:0009138 pyrimidine nucleoside diphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009138 pyrimidine nucleoside diphosphate metabolism The chemical reactions and pathways involving pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar. GO:0009137 purine nucleoside diphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009137 purine nucleoside diphosphate degradation|purine nucleoside diphosphate catabolism|purine nucleoside diphosphate breakdown The chemical reactions and pathways resulting in the breakdown of purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar. GO:0010129 anaerobic cyclohexane-1-carboxylate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010129 MetaCyc:PWY-301 anaerobic cyclohexane-1-carboxylate breakdown|anaerobic cyclohexane-1-carboxylate catabolism|anaerobic cyclohexane-1-carboxylate degradation The chemical reactions and pathways resulting in the breakdown of cyclohexane-1-carboxylate, a alicyclic acid, in the absence of oxygen. CHEBI:133979 prostaglandin D2 2-glyceryl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133979 GO:0009136 purine nucleoside diphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009136 purine nucleoside diphosphate biosynthesis|purine nucleoside diphosphate anabolism|purine nucleoside diphosphate synthesis|purine nucleoside diphosphate formation The chemical reactions and pathways resulting in the formation of purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar. GO:0009135 purine nucleoside diphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009135 purine nucleoside diphosphate metabolism The chemical reactions and pathways involving purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar. GO:0009134 nucleoside diphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009134 nucleoside diphosphate degradation|nucleoside diphosphate breakdown|nucleoside diphosphate catabolism The chemical reactions and pathways resulting in the breakdown of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar. GO:0009133 nucleoside diphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009133 nucleoside diphosphate synthesis|nucleoside diphosphate formation|nucleoside diphosphate anabolism|nucleoside diphosphate biosynthesis The chemical reactions and pathways resulting in the formation of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar. CHEBI:48058 buten-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48058 GO:0009132 nucleoside diphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009132 nucleoside diphosphate metabolism The chemical reactions and pathways involving a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar. GO:0010120 camalexin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010120 MetaCyc:CAMALEXIN-SYN camalexin anabolism|camalexin synthesis|camalexin formation|camalexin biosynthesis The chemical reactions and pathways resulting in the formation of camalexin, an indole phytoalexin. GO:0009142 nucleoside triphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009142 nucleoside triphosphate biosynthesis|nucleoside triphosphate anabolism|nucleoside triphosphate synthesis|nucleoside triphosphate formation The chemical reactions and pathways resulting in the formation of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar. CHEBI:133970 N-retinylidene-N-retinylphosphatidylethanolamine betaine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133970 GO:0009141 nucleoside triphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009141 nucleoside triphosphate metabolism The chemical reactions and pathways involving a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar. GO:0010122 arginine catabolic process to alanine via ornithine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010122 MetaCyc:ARGORNPROST-PWY arginine breakdown to alanine via ornithine|arginine degradation to alanine via ornithine The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including alanine, via ornithine. CHEBI:133972 primary nitroalkane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133972 GO:0009140 pyrimidine nucleoside diphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009140 pyrimidine nucleoside diphosphate catabolism|pyrimidine nucleoside diphosphate degradation|pyrimidine nucleoside diphosphate breakdown The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar. GO:0010121 arginine catabolic process to proline via ornithine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010121 MetaCyc:ARGORNPROST-PWY arginine breakdown to proline via ornithine|arginine degradation to proline via ornithine The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including proline, via ornithine. GO:0010124 phenylacetate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010124 MetaCyc:PWY0-321 phenylacetate degradation|phenylacetate breakdown|phenylacetate catabolism The chemical reactions and pathways resulting in the breakdown of phenylacetate. CHEBI:133974 12-oxo-6-trans-leukotriene B4(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133974 GO:0010123 acetate catabolic process to butyrate, ethanol, acetone and butanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010123 MetaCyc:CENTFERM-PWY acetate fermentation to butyrate, ethanol, acetone and butanol The anaerobic chemical reactions and pathways resulting in the breakdown of acetate to form butyrate, ethanol, acetone and butanol. GO:0010126 mycothiol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010126 mycothiol metabolism The chemical reactions and pathways involving mycothiol, which consists of N-acetyl-L-cysteine linked to a pseudodisaccharide, D-glucosamine and myo-inositol. Mycothiol is produced in actinomycetes like mycobacteria and serves similar functions to glutathione. CHEBI:24090 formyl phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_24090 GO:0010125 mycothiol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010125 MetaCyc:PWY1G-0 mycothiol biosynthesis|mycothiol anabolism|mycothiol synthesis|mycothiol formation The chemical reactions and pathways resulting in the formation of mycothiol, which consists of N-acetyl-L-cysteine linked to a pseudodisaccharide, D-glucosamine and myo-inositol. Mycothiol is produced in actinomycetes like mycobacteria and serves similar functions to glutathione. CHEBI:133975 Delta(6)-trans-12-epi-leukotriene B4(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133975 CHEBI:48041 microcystin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48041 GO:0010139 pyrimidine deoxyribonucleotide salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010139 MetaCyc:PWY0-181 The pathway by which pyrimidine bases or pyrimidine deoxyribonucleotides from pyrimidine nucleotide breakdown are converted back to pyrimidine deoxyribonucleotides. The salvage pathway is important where there is no de novo pyrimidine deoxyribonucleotide biosynthesis. CHEBI:133989 (9Z,11R,12Z,15Z)-11-hydroperoxyoctadecatrienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133989 CHEBI:133988 (9Z,11R,12Z,15Z)-11-hydroperoxyoctadecatrienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133988 GO:0009149 pyrimidine nucleoside triphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009149 pyrimidine nucleoside triphosphate degradation|pyrimidine nucleoside triphosphate breakdown|pyrimidine nucleoside triphosphate catabolism The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar. GO:0010138 pyrimidine ribonucleotide salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010138 MetaCyc:PWY0-163 The pathway by which pyrimidine bases or pyrimidine ribonucleosides from pyrimidine nucleotide breakdown are converted back to pyrimidine ribonucleotides. The salvage pathway is important where there is no de novo pyrimidine nucleotide biosynthesis. CHEBI:48040 2,3-dihydroflavon-3-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48040 GO:0009148 pyrimidine nucleoside triphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009148 pyrimidine nucleoside triphosphate synthesis|pyrimidine nucleoside triphosphate formation|pyrimidine nucleoside triphosphate anabolism|pyrimidine nucleoside triphosphate biosynthesis The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar. CHEBI:48043 (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48043 GO:0009147 pyrimidine nucleoside triphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009147 pyrimidine nucleoside triphosphate metabolism The chemical reactions and pathways involving pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar. GO:0009146 purine nucleoside triphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009146 purine nucleoside triphosphate degradation|purine nucleoside triphosphate catabolism|purine nucleoside triphosphate breakdown The chemical reactions and pathways resulting in the breakdown of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar. GO:0009145 purine nucleoside triphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009145 purine nucleoside triphosphate anabolism|purine nucleoside triphosphate synthesis|purine nucleoside triphosphate formation|purine nucleoside triphosphate biosynthesis The chemical reactions and pathways resulting in the formation of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar. CHEBI:24099 formyltetrahydrofolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24099 GO:0009144 purine nucleoside triphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009144 purine nucleoside triphosphate metabolism The chemical reactions and pathways involving purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar. GO:0009143 nucleoside triphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009143 nucleoside triphosphate degradation|nucleoside triphosphate breakdown|nucleoside triphosphate catabolism The chemical reactions and pathways resulting in the breakdown of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar. GO:0009153 purine deoxyribonucleotide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009153 purine deoxyribonucleotide biosynthesis|purine deoxyribonucleotide anabolism|purine deoxyribonucleotide synthesis|purine deoxyribonucleotide formation The chemical reactions and pathways resulting in the formation of purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. GO:0010131 obsolete sucrose catabolic process, using invertase or sucrose synthase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010131 MetaCyc:PWY-3801|MetaCyc:PWY-621 sucrose catabolic process, using invertase or sucrose synthase|sucrose breakdown, using invertase or sucrose synthase|sucrose degradation, using invertase or sucrose synthase|sucrose catabolism, using invertase or sucrose synthase OBSOLETE. The chemical reactions and pathways resulting in the breakdown of sucrose by the enzymatic action of either invertase or sucrose synthase. GO:0009152 purine ribonucleotide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009152 purine ribonucleotide anabolism|purine ribonucleotide synthesis|purine ribonucleotide formation|purine ribonucleotide biosynthesis The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. GO:0010130 anaerobic ethylbenzene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010130 MetaCyc:PWY-481 anaerobic ethylbenzene catabolism|anaerobic ethylbenzene degradation|anaerobic ethylbenzene breakdown The chemical reactions and pathways resulting in the breakdown of ethylbenzene, a benzene derivative with an ethyl group attached to the ring, which occurs in the absence of oxygen. CHEBI:133980 oxidised coenzyme F420-(gamma-Glu)n polyanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133980 GO:0010133 proline catabolic process to glutamate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010133 MetaCyc:PROUT-PWY|MetaCyc:PWY-4561 proline breakdown to glutamate|proline degradation to glutamate|proline oxidation The chemical reactions and pathways resulting in the breakdown of proline into other compounds, including glutamate. GO:0009151 purine deoxyribonucleotide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009151 purine deoxyribonucleotide metabolism The chemical reactions and pathways involving purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. GO:0010132 dhurrin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010132 MetaCyc:PWY-861 dhurrin formation|dhurrin biosynthesis|dhurrin anabolism|dhurrin synthesis The chemical reactions and pathways resulting in the formation of dhurrin, a cyanogenic glucoside which functions as a plant defense compound. GO:0009150 purine ribonucleotide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009150 purine ribonucleotide metabolism The chemical reactions and pathways involving a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. GO:0010135 ureide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010135 ureide metabolism The chemical reactions and pathways involving ureide, allantoin and allantoate, which are the organic forms of nitrogen in nitrogen fixing and transporting plants. CHEBI:133985 13(R)-HPODE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133985 GO:0010134 sulfate assimilation via adenylyl sulfate reduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010134 MetaCyc:SULFMETII-PWY sulphate assimilation via adenylyl sulphate reduction The pathway by which inorganic sulfate is activated, reduced and incorporated into sulfated compounds, where the activated sulfate, adenylyl-sulfate, is reduced to sulfite by the activity of adenylyl-sulfate reductase. GO:0010137 ureide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010137 MetaCyc:URSIN-PWY ureide anabolism|ureide synthesis|ureide formation|ureide biosynthesis The chemical reactions and pathways resulting in the formation of ureide, the organic form of nitrogen in nitrogen fixing and transporting plants, from IMP, which is synthesized de novo during nitrogen fixation by roots. CHEBI:133987 (9Z,11E,13R,15Z)-13-hydroperoxyoctadecatrienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133987 GO:0010136 ureide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010136 MetaCyc:URDEGR-PWY ureide degradation|ureide breakdown|ureide catabolism The chemical reactions and pathways resulting in the breakdown of ureide, which is the organic form of nitrogen in nitrogen fixing and transporting plants with the release of ammonium. CHEBI:133986 (9Z,11E,13R,15Z)-13-hydroperoxyoctadecatrienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133986 GO:0000783 nuclear telomere cap complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000783 A complex of DNA and protein located at the end of a linear chromosome in the nucleus that protects and stabilizes a linear chromosome. GO:0097695 establishment of protein-containing complex localization to telomere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097695 establishment of macromolecular complex localisation to telomere|establishment of macromolecular complex localization to telomere The directed movement of a protein-containing macromolecular complex to a specific location in the telomeric region of a chromosome. GO:0000782 telomere cap complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0000782 A complex of DNA and protein located at the end of a linear chromosome that protects and stabilizes a linear chromosome. GO:0097694 establishment of RNA localization to telomere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097694 establishment of RNA localisation to telomere The directed movement of RNA to a specific location in the telomeric region of a chromosome. GO:0000781 chromosome, telomeric region biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000781 SO:0000624 nuclear chromosome, telomeric region|telomere|nuclear chromosome, telomere The end of a linear chromosome, required for the integrity and maintenance of the end. A chromosome telomere usually includes a region of telomerase-encoded repeats the length of which rarely exceeds 20 bp each and that permits the formation of a telomeric loop (T-loop). The telomeric repeat region is usually preceded by a sub-telomeric region that is gene-poor but rich in repetitive elements. Some telomeres only consist of the latter part (for eg. D. melanogaster telomeres). GO:0097697 tRNA 5-carboxymethoxyuridine methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097697 Catalysis of the transfer of a methyl group from S-adenosylmethionine to a 5-carboxymethoxy-modified uridine residue in a tRNA molecule. GO:0000780 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000780 CHEBI:48039 dihydroflavonols biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48039 GO:0097696 receptor signaling pathway via STAT biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097696 STAT signalling pathway|kinase-STAT cascade|kinase activated-STAT cascade An intracellular signal transduction process in which STAT proteins (Signal Transducers and Activators of Transcription) convey a signal to trigger a change in the activity or state of a cell. The STAT cascade begins with receptor activation followed by activation of STAT proteins by kinases. It proceeds through STA dimerization and subsequent nuclear translocation of STAT proteins, and ends with regulation of target gene expression by STAT proteins. CHEBI:24068 fluoroamino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24068 GO:0097691 bacterial extracellular vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097691 Small membrane vesicle (< 1 um) that buds off a prokaryotic cell plasma membrane, able to carry proteins, phospholipids, lipopolysaccharides, nucleic acids, viruses, and more. Important in intercellular communication and pathogenesis; can exist within host cells. GO:0000787 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000787 GO:0000786 nucleosome biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0000786 Wikipedia:Nucleosome cytoplasmic nucleosome|nuclear nucleosome A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures. GO:0097690 iron ion transmembrane transporter inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097690 iron channel inhibitor activity An activity that stops, prevents, or reduces the activity of an iron ion transmembrane transporter. GO:0097693 ocelloid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097693 Eye-like subcellular structure found in dinoflagellates (a large group of single-celled eukaryotes). Consists of subcellular analogues to a cornea, lens, iris, and retina. Ocelloids are built from pre-existing organelles, including a cornea-like layer made of mitochondria and a retinal body made of anastomosing plastids. GO:0000785 chromatin biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000785 NIF_Subcellular:sao1615953555 chromosome scaffold|cytoplasmic chromatin|nuclear chromatin The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome. GO:0009119 ribonucleoside metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009119 ribonucleoside metabolism The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule. GO:0009118 regulation of nucleoside metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009118 regulation of nucleoside metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleosides. GO:0000784 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000784 GO:0097692 histone H3-K4 monomethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097692 The modification of histone H3 by addition of one methyl group to lysine at position 4 of the histone. GO:0009117 nucleotide metabolic process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0009117 nucleotide metabolism The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates). GO:0010106 cellular response to iron ion starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010106 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of iron ions. CHEBI:48030 tetrapeptide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48030 GO:0010105 negative regulation of ethylene-activated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010105 inhibition of ethylene mediated signaling pathway|negative regulation of ethene mediated signalling pathway|negative regulation of ethene mediated signaling pathway|down regulation of ethylene mediated signaling pathway|downregulation of ethylene mediated signaling pathway|negative regulation of ethylene mediated signalling pathway|down-regulation of ethylene mediated signaling pathway|negative regulation of ethylene mediated signaling pathway Any process that stops or prevents ethylene (ethene) signal transduction. CHEBI:24062 fluorine molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24062 GO:0009116 nucleoside metabolic process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0009116 nucleoside metabolism The chemical reactions and pathways involving a nucleoside, a nucleobase linked to either beta-D-ribofuranose (a ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleoside), e.g. adenosine, guanosine, inosine, cytidine, uridine and deoxyadenosine, deoxyguanosine, deoxycytidine and thymidine (= deoxythymidine). GO:0010108 detection of glutamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010108 glutamine sensing|glutamine detection|glutamine perception The series of events in which a glutamine stimulus is received by a cell and converted into a molecular signal. GO:0009115 xanthine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009115 xanthine oxidation|xanthine degradation|xanthine catabolism|xanthine breakdown The chemical reactions and pathways resulting in the breakdown of xanthine, 2,6-dihydroxypurine, a purine formed in the metabolic breakdown of guanine but not present in nucleic acids. CHEBI:24061 fluorine atom biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_24061 CHEBI:48032 4-methylene-D-glutamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48032 GO:0009114 hypoxanthine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009114 hypoxanthine degradation|hypoxanthine breakdown|hypoxanthine catabolism|hypoxanthine oxidation The chemical reactions and pathways resulting in the breakdown of hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. Its ribonucleoside is known as inosine and its ribonucleotide as inosinate. GO:0010107 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0010107 CHEBI:48031 4-methylene-L-glutamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48031 GO:0009113 purine nucleobase biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009113 MetaCyc:PWY-841 purine base anabolism|purine base synthesis|purine base formation|purine base biosynthesis|purine base biosynthetic process The chemical reactions and pathways resulting in the formation of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine. CHEBI:48034 cob(III)yrinic acid a,c diamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48034 CHEBI:24067 fluoroalkane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24067 GO:0009112 nucleobase metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009112 nucleobase metabolism The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent of a nucleic acid, e.g. the purines: adenine, guanine, hypoxanthine, xanthine and the pyrimidines: cytosine, uracil, thymine. CHEBI:133959 4'-methoxyisoflavones biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133959 GO:0010109 regulation of photosynthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010109 Any process that modulates the frequency, rate or extent of photosynthesis. CHEBI:48033 cobyrinic acid a,c diamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48033 GO:0009111 vitamin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009111 vitamin catabolism|vitamin degradation|vitamin breakdown The chemical reactions and pathways resulting in the breakdown of a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. GO:0009110 vitamin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009110 vitamin biosynthesis|vitamin anabolism|vitamin synthesis|vitamin formation The chemical reactions and pathways resulting in the formation of a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. GO:0009120 deoxyribonucleoside metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009120 deoxyribonucleoside metabolism The chemical reactions and pathways involving any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside). CHEBI:133950 (7Z,11Z,13Z,15E,19Z)-10,17-bis(hydroperoxy)docosapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133950 GO:0010100 negative regulation of photomorphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010100 down-regulation of photomorphogenesis|downregulation of photomorphogenesis|down regulation of photomorphogenesis|inhibition of photomorphogenesis Any process that stops, reduces or prevents photomorphogenesis. GO:0010102 lateral root morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010102 The process in which the anatomical structures of a lateral root are generated and organized. A lateral root is one formed from pericycle cells located on the xylem radius of the root, as opposed to the initiation of the main root from the embryo proper. GO:0010101 post-embryonic root morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010101 The process in which the anatomical structures of the post-embryonic root are generated and organized. The post-embryonic root is the root formed after the embryonic phase has been completed. GO:0010104 regulation of ethylene-activated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010104 regulation of ethene mediated signaling pathway|regulation of ethylene mediated signalling pathway|regulation of ethene mediated signalling pathway|regulation of ethylene mediated signaling pathway Any process that modulates the frequency, rate or extent of ethylene (ethene) signal transduction. GO:0010103 stomatal complex morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010103 The process in which the anatomical structures of the stomatal complex are generated and organized. The stomatal complex is the stomatal guard cells and their associated epidermal cells. GO:0000789 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000789 GO:0000788 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000788 GO:0097699 vascular endothelial cell response to fluid shear stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097699 blood vessel endothelial cell response to fluid shear stress Any response to fluid shear stress in a vascular endothelial cell. GO:0097698 telomere maintenance via base-excision repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097698 A telomere maintenance process that occurs by base-excision repair of telomeric DNA in response to DNA damage. Telomeric sequences are particularly susceptible to oxidative DNA damage, due to their G-rich nature. GO:0000794 condensed nuclear chromosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000794 nuclear mitotic chromosome|meiotic chromosome A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct nuclear chromosome. GO:0000793 condensed chromosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000793 cytoplasmic mitotic chromosome|metaphase chromosome|mitotic chromosome A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure. GO:0000792 heterochromatin biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000792 Wikipedia:Heterochromatin|NIF_Subcellular:sao581845896 nuclear heterochromatin A compact and highly condensed form of chromatin. CHEBI:48029 4-methyleneglutamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48029 GO:0000791 euchromatin biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000791 Wikipedia:Euchromatin|NIF_Subcellular:sao445485807 nuclear euchromatin A dispersed and relatively uncompacted form of chromatin. CHEBI:24079 formamides biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24079 GO:0000798 nuclear cohesin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000798 A cohesin complex required for cohesion between sister chromatids that remain in the nucleus. GO:0000797 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000797 GO:0000796 condensin complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0000796 SMC complex|13S condensin complex|condensin I complex|nuclear condensin complex|Smc2-Smc4 complex|condensin core heterodimer|8S condensin complex A multisubunit protein complex that plays a central role in chromosome condensation in meiosis and mitosis. GO:0009129 pyrimidine nucleoside monophosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009129 pyrimidine nucleoside monophosphate metabolism The chemical reactions and pathways involving pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar. GO:0000795 synaptonemal complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000795 Wikipedia:Synaptonemal_complex A proteinaceous scaffold found between homologous chromosomes during meiosis. It consists of 2 lateral elements and a central element, all running parallel to each other. Transverse filaments connect the lateral elements to the central element. GO:0009128 purine nucleoside monophosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009128 purine nucleoside monophosphate degradation|purine nucleoside monophosphate breakdown|purine nucleoside monophosphate catabolism The chemical reactions and pathways resulting in the breakdown of purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar. GO:0010117 photoprotection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010117 Protection mechanism used by plants under conditions of excess energy absorption as a consequence of the light reactions of photosynthesis. GO:0010116 positive regulation of abscisic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010116 stimulation of abscisic acid biosynthetic process|up-regulation of abscisic acid biosynthetic process|activation of abscisic acid biosynthetic process|positive regulation of abscisic acid anabolism|positive regulation of abscisic acid synthesis|positive regulation of abscisic acid formation|positive regulation of abscisic acid biosynthesis|up regulation of abscisic acid biosynthetic process|upregulation of abscisic acid biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of abscisic acid. GO:0009127 purine nucleoside monophosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009127 purine nucleoside monophosphate anabolism|purine nucleoside monophosphate synthesis|purine nucleoside monophosphate formation|purine nucleoside monophosphate biosynthesis The chemical reactions and pathways resulting in the formation of purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar. GO:0009126 purine nucleoside monophosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009126 purine nucleoside monophosphate metabolism The chemical reactions and pathways involving purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar. CHEBI:133969 5'-(N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-purine-ribonucleotide)(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133969 GO:0010119 regulation of stomatal movement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010119 Any process that modulates the frequency, rate or extent of stomatal movement. CHEBI:133968 5'-(N(7)-methyl 5'-triphosphoguanosine)-(purine-ribonucleotide)(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133968 GO:0009125 nucleoside monophosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009125 nucleoside monophosphate breakdown|nucleoside monophosphate catabolism|nucleoside monophosphate degradation The chemical reactions and pathways resulting in the breakdown of a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar. GO:0010118 stomatal movement biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0010118 The process of opening or closing of stomata, which is directly related to the stomatal conductance (measuring rate of passage of either water vapor or carbon dioxide (CO2) through stomata). GO:0009124 nucleoside monophosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009124 nucleoside monophosphate anabolism|nucleoside monophosphate synthesis|nucleoside monophosphate biosynthesis|nucleoside monophosphate formation The chemical reactions and pathways resulting in the formation of a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar. GO:0000790 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000790 GO:0009123 nucleoside monophosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009123 nucleoside monophosphate metabolism The chemical reactions and pathways involving a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar. GO:0009122 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009122 CHEBI:48025 3',5'-dihydroxyflavanone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48025 GO:0009121 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009121 CHEBI:48024 3'-hydroxyflavanones biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48024 GO:0009131 pyrimidine nucleoside monophosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009131 pyrimidine nucleoside monophosphate catabolism|pyrimidine nucleoside monophosphate degradation|pyrimidine nucleoside monophosphate breakdown The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar. GO:0009130 pyrimidine nucleoside monophosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009130 pyrimidine nucleoside monophosphate biosynthesis|pyrimidine nucleoside monophosphate anabolism|pyrimidine nucleoside monophosphate synthesis|pyrimidine nucleoside monophosphate formation The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar. GO:0010111 glyoxysome organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010111 glyoxysome organisation|glyoxysome organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the glyoxysome. A glyoxysome is a microbody that contains the enzymes of the glyoxylate pathway. GO:0010110 regulation of photosynthesis, dark reaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010110 Any process that modulates the frequency, rate or extent of photosynthesis dark reaction. GO:0010113 negative regulation of systemic acquired resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010113 downregulation of systemic acquired resistance|down regulation of systemic acquired resistance|inhibition of systemic acquired resistance|down-regulation of systemic acquired resistance Any process that stops, prevents, or reduces the frequency, rate or extent of systemic acquired resistance. GO:0010112 regulation of systemic acquired resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010112 Any process that modulates the frequency, rate or extent of systemic acquired resistance. GO:0010115 regulation of abscisic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010115 regulation of abscisic acid synthesis|regulation of abscisic acid formation|regulation of abscisic acid biosynthesis|regulation of abscisic acid anabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of abscisic acid. GO:0010114 response to red light biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010114 response to red light stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs. GO:0000799 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0000799 UBERON:0001628 posterior communicating artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001628 PCS|caudal communicating segment|posterior communicating segment of the basilar artery|arteria cerebri communicans posterior|PCA One of a pair of right-sided and left-sided blood vessels in the circle of Willis. It connects the three cerebral arteries of the same side. Anteriorly, it is one portion of the terminal trifurcation of the internal carotid artery. The anterior cerebral artery and the middle cerebral artery are the other two branches of the trifurcation. Posteriorly, it communicates with the posterior cerebral artery. GO:0000761 conjugant formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000761 During conjugation without cellular fusion, the process that results in pairing complementary mating types. Localized morphological, cytological, and cytoskeletal changes connect the mating types without cytoplasmic mixing. GO:0000760 adaptation to pheromone regulating conjugation with mutual genetic exchange biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000760 desensitization to pheromone during conjugation without cellular fusion|adaptation to pheromone involved conjugation without cellular fusion In organisms that undergo conjugation without cellular fusion, the process resulting in desensitization following exposure to pheromone stimulus that act to down-regulate further stimulation or block initial conjugation responses. GO:0000765 response to pheromone regulating pheromone-induced unidirectional conjugation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000765 response to pheromone during pheromone-induced unidirectional Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus that regulates the process of pheromone-induced unidirectional conjugation. GO:0000764 obsolete cellular morphogenesis involved in pheromone-induced unidirectional conjugation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000764 cellular morphogenesis involved in pheromone-induced unidirectional conjugation|cellular morphogenesis during pheromone-induced unidirectional OBSOLETE. The change in form (cell shape and size) that contributes to sexual reproduction in order to facilitate direct contact between the compatible mating types in organisms that undergo pheromone-induced unidirectional conjugation. GO:0000763 obsolete cell morphogenesis involved in unidirectional conjugation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000763 cell morphogenesis involved in unidirectional conjugation OBSOLETE. The change in form (cell shape and size) that occurs during sexual reproduction in order to facilitate direct contact between the compatible mating types in organisms that undergo unidirectional conjugation. GO:0000762 pheromone-induced unidirectional conjugation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000762 The process of unidirectional (polarized) transfer of genetic information in response to a pheromone. It involves direct cellular contact between a donor and recipient cell; the contact is followed by the formation of a cellular bridge that physically connects the cells; some or all of the chromosome(s) of one cell ('male') is then transferred into the other cell ('female'); unidirectional conjugation occurs between cells of different mating types. CHEBI:133934 (4Z,7Z,13Z,16Z,19Z)-10,11-epoxydocosapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133934 CHEBI:24041 flavin mononucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24041 CHEBI:133933 (4Z,7Z,10Z,16Z,19Z)-13,14-epoxydocosapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133933 CHEBI:24040 flavin adenine dinucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24040 CHEBI:133936 (7Z,10Z,13Z,19Z)-16,17-epoxydocosatetraenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133936 CHEBI:133935 (7Z,10Z,13Z,16Z)-19,20-epoxydocosatetraenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133935 CHEBI:133938 (7Z,13Z,16Z,19Z)-10,11-epoxydocosatetraenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133938 CHEBI:133937 (7Z,10Z,16Z,19Z)-13,14-epoxydocosatetraenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133937 CHEBI:24043 flavones biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_24043 CHEBI:133939 (4Z,7Z,10Z,13Z,16Z)-20-hydroxydocosapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133939 CHEBI:38687 monohydroxyflavone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38687 CHEBI:133930 5alpha-androst-1-ene-3,17-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133930 CHEBI:133932 (4Z,7Z,10Z,13Z,19Z)-16,17-epoxydocosapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133932 CHEBI:133931 (4Z,7Z,10Z,13Z,16Z)-19,20-epoxydocosapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133931 GO:0000769 syncytium formation by mitosis without cytokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000769 syncytium formation by mitosis without cell division The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by one or more rounds of nuclear division without cytokinesis. GO:0000768 syncytium formation by plasma membrane fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000768 cell fusion The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. UBERON:0001630 muscle organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001630 muscle Organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work[GO]. GO:0000767 cell morphogenesis involved in conjugation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000767 The change in form (cell shape and size) that occurs during sexual reproduction in order to facilitate direct contact between the compatible mating types. GO:0000766 negative adaptation of signaling pathway by response to pheromone involved in pheromone-induced unidirectional conjugation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000766 desensitization to pheromone during pheromone-induced unidirectional conjugation|negative adaptation of signalling pathway by response to pheromone involved in pheromone-induced unidirectional conjugation|adaptation to pheromone during pheromone-induced unidirectional conjugation In organisms that undergo pheromone-induced unidirectional conjugation, the process involved in desensitization following exposure to pheromone stimulus that acts to down-regulate further stimulation or block initial conjugation responses. CHEBI:38686 dihydroxyflavone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38686 CHEBI:38685 1,2-epoxypropane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38685 CHEBI:38684 tetrahydroxyflavone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38684 GO:0000772 mating pheromone activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000772 The activity of binding to and activating specific cell surface receptors, thereby inducing a behavioral or physiological response(s) from a responding organism or cell that leads to the transfer or union of genetic material between organisms or cells. The mating pheromone can either be retained on the cell surface or secreted. CHEBI:48005 gamma-L-glutamylputrescine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48005 GO:0000771 agglutination involved in conjugation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000771 The aggregation or adhesion of compatible mating types via complementary cell-cell interactions prior to the formation of irreversible cellular contacts during conjugation. UBERON:0001616 maxillary artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001616 internal maxillary artery|arteria maxillaris An artery that supplies deep structures of the face. It comes just out behind the neck of the mandible. [WP,unvetted]. CHEBI:24059 fluorenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24059 GO:0000770 peptide pheromone export biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000770 a-factor export The directed movement of a peptide pheromone out of a cell by a secretion or export pathway used solely for the export of peptide pheromones. UBERON:0001619 ophthalmic artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001619 arteria ophthalmica|opthalmic artery The ophthalmic artery is a branch of the internal carotid artery which supplies branches to supply the eye and other structures in the orbit. It enters the orbit together with the Optic nerve through the Optic foramen/canal. [WP,modified]. CHEBI:48007 N-[(E)-4-aminobutylidene]propane-1,3-diamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48007 CHEBI:24057 fluoren-9-ones biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24057 CHEBI:48006 gamma-glutamylputrescine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48006 GO:0000776 kinetochore biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0000776 Wikipedia:Kinetochore A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules. GO:0000775 chromosome, centromeric region biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000775 SO:0000577 chromosome, centric region|centromere|chromosome, pericentric region|centromere complex The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome. GO:0009109 obsolete coenzyme catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009109 coenzyme degradation|coenzyme and prosthetic group catabolic process|coenzyme breakdown|coenzyme and prosthetic group catabolism|coenzyme catabolism OBSOLETE. The chemical reactions and pathways resulting in the breakdown of coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed. UBERON:0001612 facial artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001612 external maxillary artery|arteria maxillaris externa A branch of the external carotid artery that supplies structures of the face. [WP,unvetted]. GO:0009108 obsolete coenzyme biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009108 coenzyme anabolism|coenzyme and prosthetic group biosynthetic process|coenzyme and prosthetic group biosynthesis|coenzyme biosynthesis|coenzyme synthesis|coenzyme formation OBSOLETE. The chemical reactions and pathways resulting in the formation of coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed. GO:0000774 adenyl-nucleotide exchange factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000774 Reactome:R-HSA-5252079 Stimulates the hydrolysis and exchange of adenyl nucleotides by other proteins. GO:0009107 lipoate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009107 lipoate biosynthesis|lipoate anabolism|lipoate synthesis|lipoate formation|lipoic acid biosynthetic process|lipoic acid biosynthesis|lipoic acid anabolism|lipoic acid synthesis|lipoic acid formation The chemical reactions and pathways resulting in the formation of lipoate, 1,2-dithiolane-3-pentanoate, the anion derived from lipoic acid. GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0000773 RHEA:32735|EC:2.1.1.71|MetaCyc:2.1.1.71-RXN phosphatidylethanolamine methyltransferase I|methyltransferase II|phospholipid methyltransferase activity|S-adenosyl-L-methionine:phosphatidyl-N-methylethanolamine N-methyltransferase activity|PLMT|phosphatidyl-N-methylethanolamine methyltransferase activity|phosphatidylmonomethylethanolamine methyltransferase activity|phosphatidyl-N-monomethylethanolamine methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine = S-adenosyl-L-homocysteine + phosphatidyl-N-dimethylethanolamine. GO:0009106 lipoate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009106 lipoate metabolism|lipoic acid metabolic process|lipoic acid metabolism The chemical reactions and pathways involving lipoate, 1,2-dithiolane-3-pentanoate, the anion derived from lipoic acid. GO:0009105 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009105 GO:0009104 lipopolysaccharide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009104 lipopolysaccharide degradation|LPS catabolic process|lipopolysaccharide breakdown|lipopolysaccharide catabolism The chemical reactions and pathways resulting in the breakdown of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. GO:0009103 lipopolysaccharide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009103 KEGG_PATHWAY:map00540 lipopolysaccharide biosynthesis|lipopolysaccharide anabolism|LPS biosynthetic process|lipopolysaccharide synthesis|lipopolysaccharide formation The chemical reactions and pathways resulting in the formation of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. GO:0009102 biotin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009102 MetaCyc:BIOTIN-SYNTHESIS-PWY vitamin H biosynthesis|vitamin H biosynthetic process|vitamin B7 biosynthesis|vitamin B7 biosynthetic process|biotin anabolism|biotin synthesis|biotin formation|biotin biosynthesis The chemical reactions and pathways resulting in the formation of biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid. CHEBI:48001 protein synthesis inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48001 CHEBI:133949 (4Z,7Z,11Z,13Z,15E,17S)-10,17-bis(hydroperoxy)docosapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133949 GO:0009101 glycoprotein biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009101 glycoprotein biosynthesis|glycoprotein anabolism|glycoprotein synthesis|glycoprotein formation The chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. CHEBI:133948 (4Z,7Z,11Z,13Z,15E,17S,19Z)-10,17-bis(hydroperoxy)docosahexaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133948 CHEBI:48000 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48000 GO:0009100 glycoprotein metabolic process biolink:BiologicalProcess go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0009100 glycoprotein metabolism The chemical reactions and pathways involving glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. CHEBI:133941 (3S,5R,10R,12S,14S,15R,16R)-3,5,10,14,15-pentahydroxy-12,16-dimethylicosan-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133941 CHEBI:133940 lithocholate sulfate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133940 GO:0000779 condensed chromosome, centromeric region biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000779 condensed chromosome, pericentric region|condensed chromosome, centric region|condensed chromosome, centromere|condensed nuclear chromosome, centromeric region The region of a condensed chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome. CHEBI:38691 flavan biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38691 GO:0000778 condensed nuclear chromosome kinetochore biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000778 A multisubunit complex that is located at the centromeric region of a condensed nuclear chromosome and provides an attachment point for the spindle microtubules. UBERON:0001622 lacrimal artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001622 a. lacrimalis The lacrimal artery arises close to the optic foramen, and is one of the largest branches derived from the ophthalmic artery: not infrequently it is given off before the artery enters the orbit. It accompanies the lacrimal nerve along the upper border of the Lateral Rectus, supplies the lacrimal gland. [WP,unvetted]. UBERON:0001621 coronary artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001621 coronary vessel|coronary arterial tree An artery that supplies the myocardium. GO:0000777 condensed chromosome kinetochore biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0000777 A multisubunit complex that is located at the centromeric region of a condensed chromosome and provides an attachment point for the spindle microtubules. CHEBI:38697 anthocyanin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38697 CHEBI:38695 anthocyanidin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38695 UBERON:0001606 muscle of iris biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001606 iris muscle|muscle organ of iris|iris muscle organ . CHEBI:24027 fatty-acyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24027 UBERON:0001605 ciliary muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001605 Bowman`s muscles|ciliaris|musculus ciliaris|musculus ciliarus The ciliary muscle is a ring of smooth muscle in the middle layer of the eye that controls the eye's accommodation for viewing objects at varying distances and regulates the flow of aqueous humour through Schlemm's canal. [WP,unvetted]. CHEBI:24026 fatty alcohol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24026 UBERON:0001608 dilatator pupillae biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001608 pupillary dilator|pupillary muscle|iris dilator muscle|pupil dilator muscle|musculus dilatator pupillae|musculus dilator pupillae|dilator muscle of pupil|radial muscle of iris|radial muscle|dilator pupillae muscle|iris dilator|pupillary dilator muscle|dilator of pupil|radiating fibers|dilator pupillae muscle|pupil dilator|dilator pupillae|musculus dilatator pupillae A smooth muscle of the eye, running radially in the iris that functions as a dilator. [WP,unvetted]. UBERON:0001607 sphincter pupillae biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001607 circular fibers|sphincter muscle of pupil|spincter pupillae|iris sphincter|iris constrictor|sphincter pupillae muscle|pupillary sphincter muscle|pupillary constrictor muscle|M. sphincter pupillae|pupillary sphincter|iris sphincter muscle|constrictor pupillae|sphincter pupillae|m. sphincter pupillae|iris constrictor muscle|musculus sphincter pupillae A sphincter muscle that is part of the iris. GO:0000743 nuclear migration involved in conjugation with cellular fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000743 nuclear congression|nuclear migration during conjugation with cellular fusion The microtubule-based movement of nuclei towards one another as a prelude to karyogamy in organisms undergoing conjugation with cellular fusion. UBERON:0001602 medial rectus extraocular muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001602 musculus rectus medialis|medial rectus|musculus rectus medialis bulbi|medial rectus muscle|m. rectus medialis|medial rectus extraocular muscle|medial recti The medial rectus muscle is a muscle in the orbit. As with most of the muscles of the orbit, it is innervated by the inferior division of the oculomotor nerve (Cranial Nerve III). This muscle shares an origin with several other extrinsic eye muscles, the anulus tendineus, or common tendon. It is the largest of the extraocular muscles and its only action is adduction of the eyeball. [WP,unvetted]. GO:0000742 karyogamy involved in conjugation with cellular fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000742 karyogamy during conjugation with cellular fusion During sexual reproduction, the creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei. This occurs after cytogamy. UBERON:0001601 extra-ocular muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001601 musculi externi bulbi oculi|extraocular musculature|extra-ocular skeletal muscle|extrinsic muscle of eyeball|extrinsic ocular muscle|extrinsic eye muscle|extraocular muscle|extraocular skeletal muscle Skeletal muscle derived from cranial mesoderm and controls eye movements. GO:0000741 karyogamy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000741 Wikipedia:Karyogamy nuclear fusion|nuclear fusion during karyogamy The creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei. GO:0000740 nuclear membrane fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000740 The joining of 2 or more lipid bilayer membranes that surround the nucleus. UBERON:0001603 lateral rectus extra-ocular muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001603 lateral rectus extraocular muscle|lateral recti|musculus rectus lateralis|musculus rectus lateralis bulbi|lateral rectus|lateral extraocular muscle|lateral rectus muscle|posterior rectus|M. rectus lateralis The lateral rectus muscle is a muscle in the orbit. It is one of six extraocular muscles that control the movements of the eye (abduction in this case) and the only muscle innervated by the abducens nerve, cranial nerve VI. [WP,unvetted]. CHEBI:24028 iron(3+) chelator biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24028 CHEBI:133912 alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133912 CHEBI:133911 alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133911 CHEBI:133917 ochratoxin alpha biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133917 CHEBI:24020 fat-soluble vitamin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24020 CHEBI:38668 purinecarboxylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38668 CHEBI:38667 purinemonocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38667 CHEBI:133910 2-trans-abscisic acid D-glucosyl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133910 GO:0000747 conjugation with cellular fusion biolink:BiologicalProcess go-plus goslim_pombe http://purl.obolibrary.org/obo/GO_0000747 cell fusion|mating A conjugation process that results in the union of cellular and genetic information from compatible mating types. An example of this process is found in Saccharomyces cerevisiae. GO:0000746 conjugation biolink:BiologicalProcess go-plus goslim_yeast|goslim_candida|goslim_pir|goslim_aspergillus http://purl.obolibrary.org/obo/GO_0000746 Wikipedia:Conjugation The union or introduction of genetic information from compatible mating types that results in a genetically different individual. Conjugation requires direct cellular contact between the organisms. GO:0000745 nuclear migration involved in conjugation with mutual genetic exchange biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000745 nuclear exchange during conjugation without cellular fusion|nuclear migration involved in conjugation without cellular fusion The net movement of nuclei towards one another, leading to the bilateral transfer of genetic material in organisms undergoing conjugation without cellular fusion. GO:0000744 karyogamy involved in conjugation with mutual genetic exchange biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000744 karyogamy involved in conjugation without cellular fusion During sexual reproduction, the creation of a single nucleus from two nuclei as a result of fusing the nuclear envelopes that surround each nuclei. This takes place following the mutual exchange of one of the two nuclei produced by the mitosis that follows the second meiotic nuclear division. This occurs in ciliated protozoans such as Tetrahymena. UBERON:0001610 lingual artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001610 lingual branch of external carotid artery|arteria lingualis The lingual artery arises from the external carotid between the superior thyroid and facial artery[WP]. GO:0000749 response to pheromone triggering conjugation with cellular fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000749 response to pheromone during conjugation with cellular fusion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus that positively regulates the process of conjugation with cellular fusion. An example of this process is found in Saccharomyces cerevisiae. GO:0000748 conjugation with mutual genetic exchange biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000748 conjugation without cellular fusion A conjugation process that results in the mutual exchange and union of only genetic information between compatible mating types. Conjugation without cellular fusion requires direct cellular contact between the organisms without plasma membrane fusion. The organisms involved in conjugation without cellular fusion separate after nuclear exchange. GO:0000750 pheromone-dependent signal transduction involved in conjugation with cellular fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000750 transduction of mating signal A signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion. An example of this process is found in Saccharomyces cerevisiae. GO:0000754 adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000754 adaptation to pheromone during conjugation with cellular fusion|adaptation of signalling pathway by response to pheromone involved in conjugation with cellular fusion|desensitization to pheromone during conjugation with cellular fusion In organisms that undergo conjugation with cellular fusion, the process resulting in desensitization following exposure to pheromone stimulus that act to down-regulate further stimulation or block initial conjugation responses. An example of this is the adaptation to pheromone during conjugation with cellular fusion in Saccharomyces cerevisiae. GO:0000753 cell morphogenesis involved in conjugation with cellular fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000753 shmooing|shmoo orientation The change in form (cell shape and size) that occurs during sexual reproduction in order to facilitate direct contact between the compatible mating types in organisms that undergo conjugation cellular fusion. GO:0000752 agglutination involved in conjugation with cellular fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000752 agglutination|cell-cell adhesion during conjugation with cellular fusion|cell-cell adhesion during mating The aggregation or adhesion of compatible mating types via complementary cell-cell interactions during conjugation with cellular fusion of a unicellular organism. An example of this process is agglutination in Saccharomyces cerevisiae. GO:0000751 mitotic cell cycle G1 arrest in response to pheromone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000751 cell cycle arrest in response to pheromone The cell cycle regulatory process in which the mitotic cell cycle is halted during G1 as a result of a pheromone stimulus. An example of this process is found in Saccharomyces cerevisiae. CHEBI:133927 glycolaldehyde phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133927 CHEBI:133929 3,4-bis(7-chloroindol-3-yl)-2,5-diiminiohexanedioate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133929 CHEBI:24031 ferulic acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24031 CHEBI:133928 2,5-diiminio-3,4-bis(indol-3-yl)hexanedioate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133928 CHEBI:38679 fluorobiphenyl biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38679 CHEBI:63606 (6S)-5-formyltetrahydrofolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63606 GO:0000758 agglutination involved in conjugation with mutual genetic exchange biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000758 sexual flocculation|agglutination involved in conjugation without cellular fusion The aggregation or adhesion of compatible mating types via complementary cell-cell interactions during conjugation without cellular fusion of a unicellular organism. GO:0000757 obsolete signal transduction involved in regulation of conjugation with mutual genetic exchange biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000757 signal transduction involved in conjugation without cellular fusion OBSOLETE. A signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation without cellular fusion. CHEBI:38670 pyrrolopyrimidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38670 GO:0000756 response to pheromone regulating conjugation with mutual genetic exchange biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000756 response to pheromone triggering conjugation without cellular fusion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus regulating the process of conjugation without cellular fusion. GO:0000755 cytogamy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000755 zygote formation During conjugation with cellular fusion, the process resulting in creating a single cell from complementary mating types. The localized remodeling and dissolution of external protective structures allow the fusion of the plasma membranes and cytoplasmic mixing. An example of this process is found in Saccharomyces cerevisiae. CHEBI:38674 chromenemonocarboxylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38674 CHEBI:38672 flavans biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38672 GO:0000759 obsolete cell morphogenesis involved in conjugation with mutual genetic exchange biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0000759 cellular morphogenesis involved in conjugation without cellular fusion OBSOLETE. The change in form (cell shape and size) that occurs during sexual reproduction in order to facilitate direct contact between the compatible mating types in organisms that undergo conjugation without cellular fusion. GO:0097631 integral component of omegasome membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097631 omegasome integral membrane protein|integral to omegasome membrane The component of the omegasome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0097630 intrinsic component of omegasome membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097630 intrinsic to omegasome membrane The component of the omegasome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:1903869 negative regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903869 down-regulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|downregulation of 5,10-CH(2)-H(4)folate reductase activity|down regulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|negative regulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|down regulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|downregulation of N5,N10-methylenetetrahydrofolate reductase activity|downregulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|inhibition of 5,10-methylenetetrahydropteroylglutamate reductase activity|down regulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|downregulation of methylenetetrahydrofolate reductase (NADPH(2)) activity|inhibition of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|inhibition of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|down regulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|downregulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|down regulation of MetF|down-regulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|negative regulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|down regulation of 5,10-CH(2)-H(4)folate reductase activity|downregulation of 5,10-CH2-H4folate reductase activity|downregulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|downregulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|downregulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|down regulation of methylenetetrahydrofolate reductase [NAD(P)H]|downregulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|down regulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|inhibition of 5,10-CH(2)-H(4)folate reductase activity|inhibition of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|negative regulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|down regulation of 5,10-CH2-H4folate reductase activity|inhibition of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|down-regulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|down regulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|down regulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|inhibition of MetF|negative regulation of methylenetetrahydrofolate reductase (NADPH(2)) activity|negative regulation of methylenetetrahydrofolate reductase (NADPH2)|down-regulation of methylenetetrahydrofolate reductase (NADPH(2)) activity|negative regulation of N5,10-methylenetetrahydrofolate reductase activity|down-regulation of N5,10-methylenetetrahydrofolate reductase activity|down-regulation of methylenetetrahydrofolate reductase (NADPH2)|negative regulation of N5,N10-methylenetetrahydrofolate reductase activity|down-regulation of N5,N10-methylenetetrahydrofolate reductase activity|down-regulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|inhibition of 5,10-CH2-H4folate reductase activity|downregulation of methylenetetrahydrofolate reductase [NAD(P)H]|negative regulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|inhibition of 5,10-methylenetetrahydrofolate reductase (FADH) activity|down-regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity|downregulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|negative regulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|down-regulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|downregulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|down regulation of 5,10-methylenetetrahydropteroylglutamate reductase activity|down-regulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|negative regulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|down-regulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|down-regulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|negative regulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|negative regulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|down-regulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|negative regulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|down regulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|downregulation of 5,10-methylenetetrahydropteroylglutamate reductase activity|inhibition of N5,N10-methylenetetrahydrofolate reductase activity|inhibition of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|inhibition of methylenetetrahydrofolate reductase (NADPH(2)) activity|downregulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|inhibition of 5-methyltetrahydrofolate:NAD oxidoreductase activity|down-regulation of methylenetetrahydrofolate reductase [NAD(P)H]|downregulation of N5,10-methylenetetrahydrofolate reductase activity|down-regulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|negative regulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|down regulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|downregulation of methylenetetrahydrofolate reductase (NADPH2)|negative regulation of methylenetetrahydrofolate reductase [NAD(P)H]|downregulation of methylenetetrahydrofolate reductase (NAD(P)H) activity|negative regulation of MetF|down regulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|inhibition of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|down-regulation of MetF|negative regulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|downregulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|down-regulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|inhibition of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|down regulation of N5,10-methylenetetrahydrofolate reductase activity|inhibition of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|down-regulation of 5,10-CH(2)-H(4)folate reductase activity|downregulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|negative regulation of 5,10-CH(2)-H(4)folate reductase activity|downregulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|down regulation of methylenetetrahydrofolate reductase (NADPH2)|inhibition of methylenetetrahydrofolate reductase (NADPH2)|negative regulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|down-regulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|down regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity|inhibition of N5,10-methylenetetrahydrofolate reductase activity|negative regulation of 5,10-methylenetetrahydropteroylglutamate reductase activity|inhibition of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|down regulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|down-regulation of 5,10-methylenetetrahydropteroylglutamate reductase activity|down-regulation of 5,10-CH2-H4folate reductase activity|down regulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|inhibition of methylenetetrahydrofolate reductase (NAD(P)H) activity|negative regulation of 5,10-CH2-H4folate reductase activity|down-regulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|inhibition of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|negative regulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|downregulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|inhibition of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|down regulation of methylenetetrahydrofolate reductase (NADPH(2)) activity|down regulation of N5,N10-methylenetetrahydrofolate reductase activity|down regulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|downregulation of MetF|inhibition of methylenetetrahydrofolate reductase [NAD(P)H] Any process that stops, prevents or reduces the frequency, rate or extent of methylenetetrahydrofolate reductase (NAD(P)H) activity. GO:1903868 regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903868 regulation of MetF|regulation of 5,10-CH(2)-H(4)folate reductase activity|regulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|regulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|regulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|regulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|regulation of 5,10-CH2-H4folate reductase activity|regulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|regulation of methylenetetrahydrofolate reductase [NAD(P)H]|regulation of 5,10-methylenetetrahydrofolic acid reductase activity|regulation of methylenetetrahydrofolate reductase activity|regulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|regulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|regulation of MTHFR activity|regulation of 5,10-methylenetetrahydropteroylglutamate reductase activity|regulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|regulation of N(5),N(10)-methylenetetrahydrofolate reductase activity|regulation of methylenetetrahydrofolate reductase (NADPH2)|regulation of N5,10-methylenetetrahydrofolate reductase activity|regulation of N(5,10)-methylenetetrahydrofolate reductase activity|regulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|regulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|regulation of 5,10-methylenetetrahydrofolate reductase activity|regulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|regulation of methylenetetrahydrofolic acid reductase activity|regulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|regulation of methylenetetrahydrofolate reductase (NADPH(2)) activity|regulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|regulation of N5,N10-methylenetetrahydrofolate reductase activity Any process that modulates the frequency, rate or extent of methylenetetrahydrofolate reductase (NAD(P)H) activity. GO:1903867 extraembryonic membrane development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903867 The process whose specific outcome is the progression of an extraembryonic membrane over time, from its formation to the mature structure. GO:1903866 palisade mesophyll development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903866 palisade parenchyma development The process whose specific outcome is the progression of a palisade mesophyll over time, from its formation to the mature structure. GO:1903865 sigma factor antagonist complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1903865 A protein complex which is capable of sigma factor antagonist activity. GO:1903864 P granule disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903864 polar granule disassembly|germline granule disassembly The disaggregation of a P granule into its constituent components. GO:1903863 P granule assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903863 germline granule formation|polar granule assembly|polar granule formation|germline granule assembly|P granule formation The aggregation, arrangement and bonding together of a set of components to form a P granule. GO:1903862 positive regulation of oxidative phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903862 up regulation of oxidative phosphorylation|activation of oxidative phosphorylation|up regulation of respiratory-chain phosphorylation|positive regulation of respiratory-chain phosphorylation|activation of respiratory-chain phosphorylation|up-regulation of oxidative phosphorylation|up-regulation of respiratory-chain phosphorylation|upregulation of oxidative phosphorylation|upregulation of respiratory-chain phosphorylation Any process that activates or increases the frequency, rate or extent of oxidative phosphorylation. GO:1903861 positive regulation of dendrite extension biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903861 upregulation of dendrite extension|activation of dendrite extension|up-regulation of dendrite extension|up regulation of dendrite extension Any process that activates or increases the frequency, rate or extent of dendrite extension. GO:1903860 negative regulation of dendrite extension biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903860 downregulation of dendrite extension|up-regulation of dendrite retraction|down regulation of dendrite extension|inhibition of dendrite extension|up regulation of dendrite retraction|down-regulation of dendrite extension Any process that stops, prevents or reduces the frequency, rate or extent of dendrite extension. GO:0009099 valine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009099 MetaCyc:VALSYN-PWY valine anabolism|valine synthesis|valine formation|valine biosynthesis The chemical reactions and pathways resulting in the formation of valine, 2-amino-3-methylbutanoic acid. GO:1903870 positive regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903870 positive regulation of 5,10-methylenetetrahydropteroylglutamate reductase activity|activation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|up-regulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|activation of 5,10-methylenetetrahydropteroylglutamate reductase activity|positive regulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|upregulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|up regulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|positive regulation of MetF|upregulation of N5,N10-methylenetetrahydrofolate reductase activity|upregulation of methylenetetrahydrofolate reductase (NADPH(2)) activity|up regulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|upregulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|up-regulation of methylenetetrahydrofolate reductase [NAD(P)H]|upregulation of N5,10-methylenetetrahydrofolate reductase activity|upregulation of methylenetetrahydrofolate reductase (NADPH2)|up regulation of MetF|positive regulation of 5,10-CH(2)-H(4)folate reductase activity|positive regulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|upregulation of methylenetetrahydrofolate reductase (NAD(P)H) activity|up-regulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|activation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|up-regulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|up regulation of 5,10-CH(2)-H(4)folate reductase activity|activation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|positive regulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|upregulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|upregulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|upregulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|upregulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|up regulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|upregulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|positive regulation of 5,10-CH2-H4folate reductase activity|positive regulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|up-regulation of 5,10-methylenetetrahydropteroylglutamate reductase activity|up regulation of 5,10-CH2-H4folate reductase activity|up-regulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|activation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|up regulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|upregulation of methylenetetrahydrofolate reductase [NAD(P)H]|up-regulation of N5,10-methylenetetrahydrofolate reductase activity|upregulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|up-regulation of methylenetetrahydrofolate reductase (NADPH2)|up regulation of N5,N10-methylenetetrahydrofolate reductase activity|up regulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|activation of methylenetetrahydrofolate reductase (NADPH2)|up regulation of methylenetetrahydrofolate reductase (NADPH(2)) activity|activation of N5,10-methylenetetrahydrofolate reductase activity|upregulation of MetF|up-regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity|activation of methylenetetrahydrofolate reductase (NAD(P)H) activity|activation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|activation of methylenetetrahydrofolate reductase (NADPH(2)) activity|upregulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|positive regulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|activation of N5,N10-methylenetetrahydrofolate reductase activity|positive regulation of methylenetetrahydrofolate reductase (NADPH(2)) activity|up-regulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|positive regulation of N5,N10-methylenetetrahydrofolate reductase activity|activation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|up-regulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|positive regulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|upregulation of 5,10-CH(2)-H(4)folate reductase activity|up-regulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|up regulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|up regulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|up regulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|up regulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|upregulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|activation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|positive regulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|upregulation of 5,10-methylenetetrahydropteroylglutamate reductase activity|positive regulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|upregulation of 5,10-CH2-H4folate reductase activity|positive regulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|activation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|positive regulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|up-regulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|upregulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|activation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|activation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|up regulation of methylenetetrahydrofolate reductase [NAD(P)H]|up regulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|positive regulation of N5,10-methylenetetrahydrofolate reductase activity|up-regulation of MetF|positive regulation of methylenetetrahydrofolate reductase (NADPH2)|activation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|positive regulation of methylenetetrahydrofolate reductase [NAD(P)H]|up-regulation of 5,10-CH(2)-H(4)folate reductase activity|up regulation of methylenetetrahydrofolate reductase (NADPH2)|up regulation of N5,10-methylenetetrahydrofolate reductase activity|upregulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|up regulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|activation of 5,10-CH(2)-H(4)folate reductase activity|up-regulation of methylenetetrahydrofolate reductase (NADPH(2)) activity|positive regulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|up-regulation of N5,N10-methylenetetrahydrofolate reductase activity|up-regulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|activation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|positive regulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|positive regulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|up regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity|up-regulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|activation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|upregulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|up regulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|up-regulation of 5,10-CH2-H4folate reductase activity|activation of methylenetetrahydrofolate reductase [NAD(P)H]|activation of MetF|up regulation of 5,10-methylenetetrahydropteroylglutamate reductase activity|up regulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|up-regulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|up-regulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|up-regulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|activation of 5,10-CH2-H4folate reductase activity Any process that activates or increases the frequency, rate or extent of methylenetetrahydrofolate reductase (NAD(P)H) activity. GO:0010087 phloem or xylem histogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010087 vascular tissue histogenesis|vascular tissue development The process whose specific outcome is the progression of phloem and/or xylem over time, from formation to the mature structure. An example of this process is found in Arabidopsis thaliana. GO:0034054 suppression by symbiont of host defense-related programmed cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034054 suppression of HR|negative regulation by symbiont of host defense-related programmed cell death|inhibition of host defense-related PCD|suppression by symbiont of host defense-related programmed cell death|negative regulation by symbiont of host defense-related PCD|down-regulation by symbiont of host defense-related programmed cell death|inhibition of HR|negative regulation by symbiont of plant hypersensitive response|downregulation by symbiont of host defense-related programmed cell death|inhibition by symbiont of host defense-related PCD|down regulation by symbiont of host defense-related programmed cell death|inhibition by symbiont of host defense-related programmed cell death|negative regulation by symbiont of plant HR|inhibition of hypersensitive response Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of defense-related programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0034053 modulation by symbiont of host defense-related programmed cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034053 modulation by symbiont of host defense-related PCD|modulation by symbiont of host hypersensitive response|modulation by symbiont of plant HR|modulation by symbiont of host HR|modulation by symbiont of plant hypersensitive response Any process in which a symbiont modulates the frequency, rate or extent of defense-related programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0010086 embryonic root morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010086 The process in which the anatomical structures of the embryonic root are generated and organized. GO:0010089 xylem development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010089 xylem histogenesis The formation of the principal water-conducting tissue of a vascular plant. GO:0034052 positive regulation of plant-type hypersensitive response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034052 up regulation of plant-type hypersensitive response|positive regulation of plant hypersensitive response|positive regulation of HR|positive regulation of HR-PCD|upregulation of plant-type hypersensitive response|stimulation of plant-type hypersensitive response|activation of plant-type hypersensitive response|up-regulation of plant-type hypersensitive response Any process that activates or increases the frequency, rate or extent of the hypersensitive response in a plant. GO:0010088 phloem development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010088 phloem histogenesis The formation of the principal food-conducting tissue of a vascular plant. GO:0034051 negative regulation of plant-type hypersensitive response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034051 negative regulation of HR-PCD|downregulation of plant-type hypersensitive response|negative regulation of HR|down regulation of plant-type hypersensitive response|negative regulation of plant hypersensitive response|inhibition of plant-type hypersensitive response|down-regulation of plant-type hypersensitive response Any process that stops, prevents, or reduces the frequency, rate or extent of the hypersensitive response in a plant. GO:0034050 programmed cell death induced by symbiont biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034050 'host programmed cell death induced by symbiont' Cell death resulting from activation of endogenous cellular processes after interaction with a symbiont (defined as the smaller of two, or more, organisms engaged in symbiosis, a close interaction encompassing mutualism through parasitism). This can be triggered by direct interaction with the organism, for example, contact with penetrating hyphae of a fungus; or an indirect interaction such as symbiont-secreted molecules. GO:0097637 integral component of autophagosome membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097637 autophagic vacuole integral membrane protein|integral to autophagic vacuole membrane|integral component of autophagic vacuole membrane The component of the autophagosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0097636 intrinsic component of autophagosome membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097636 intrinsic to autophagic vacuole membrane|intrinsic component of autophagic vacuole membrane The component of the autophagosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0097639 L-lysine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097639 L-lysine import into cell The directed movement of L-lysine from outside of a cell, across the plasma membrane and into the cytosol. GO:0010081 regulation of inflorescence meristem growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010081 regulation of inflorescence meristem size Any process involved in maintaining the size and shape of an inflorescence meristem. GO:0010080 regulation of floral meristem growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010080 regulation of floral meristem size Any process involved in maintaining the size and shape of a floral meristem. GO:0097638 L-arginine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097638 L-arginine import into cell|arginine import The directed movement of L-arginine from outside of a cell, across the plasma membrane and into the cytosol. GO:0034059 response to anoxia biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034059 response to anoxic stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%. GO:0034058 endosomal vesicle fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034058 endosome vesicle fusion The homotypic fusion of endocytic vesicles to form or add to an early endosome. GO:0010083 regulation of vegetative meristem growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010083 regulation of vegetative meristem size Any process involved in maintaining the size and shape of a vegetative meristem. GO:0097633 intrinsic component of phagophore assembly site membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097633 intrinsic to phagophore assembly site membrane The component of the phagophore assembly site membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0097632 extrinsic component of phagophore assembly site membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097632 extrinsic component of pre-autophagosomal structure membrane|extrinsic to phagophore assembly site membrane|phagophore assembly site peripheral membrane The component of the phagophore assembly site membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:0034057 RNA strand-exchange activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034057 Facilitates the displacement of one strand of an RNA-RNA duplex and its replacement with a different strand of higher complementarity. GO:0010082 regulation of root meristem growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010082 regulation of root meristem size Any process involved in maintaining the size and shape of a root meristem. GO:0097635 extrinsic component of autophagosome membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097635 autophagic vacuole peripheral membrane|extrinsic to autophagic vacuole membrane|extrinsic component of autophagic vacuole membrane The component of the autophagosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:0010085 polarity specification of proximal/distal axis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010085 Any process resulting in the establishment of polarity along the proximal/distal axis. GO:0034056 estrogen response element binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034056 ERE binding Interacting selectively and non-covalently with the estrogen response element (ERE), a conserved sequence found in the promoters of genes whose expression is regulated in response to estrogen. GO:0097634 integral component of phagophore assembly site membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097634 phagophore assembly site integral membrane protein|integral to phagophore assembly site membrane The component of the phagophore assembly site membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0034055 effector-mediated induction of programmed cell death in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034055 stimulation by symbiont of host defense-related programmed cell death|up-regulation by symbiont of host defense-related programmed cell death|activation by symbiont of host defense-related programmed cell death|positive regulation by symbiont of host defense-related PCD|enhancement by symbiont of host defense-related programmed cell death|positive regulation by symbiont of host defense-related programmed cell death|up regulation by symbiont of host defense-related programmed cell death|upregulation by symbiont of host defense-related programmed cell death A symbiont process in which a molecule secreted by the symbiont activates a programmed cell death pathway in the host to suppress the host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0010084 specification of animal organ axis polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010084 The process in which the polarity of an animal organ axis is specified. GO:0097640 L-ornithine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097640 L-ornithine import into cell The directed movement of L-ornithine from outside of a cell, across the plasma membrane and into the cytosol. GO:0097642 calcitonin family receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097642 Combining with any member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)) to initiate a change in cell activity. GO:0097641 alpha-ketoglutarate-dependent xanthine dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097641 RHEA:43120 alpha-ketoglutarate- and Fe(II)-dependent xanthine hydroxylase activity|2-oxoglutarate-dependent xanthine dioxygenase activity|alpha-ketoglutarate- and Fe(II)-dependent xanthine dioxygenase activity Catalysis of the reaction: 2-oxoglutarate (alpha-ketoglutarate) + O2 + xanthine = CO2 + succinate + urate. GO:1903879 11beta-hydroxyprogesterone binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1903879 Interacting selectively and non-covalently with 11beta-hydroxyprogesterone. GO:1903878 11-deoxycorticosterone binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1903878 Interacting selectively and non-covalently with 11-deoxycorticosterone. GO:1903877 21-deoxycortisol binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1903877 Interacting selectively and non-covalently with 21-deoxycortisol. GO:1903876 11-deoxycortisol binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1903876 Interacting selectively and non-covalently with 11-deoxycortisol. GO:1903875 corticosterone binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1903875 Interacting selectively and non-covalently with corticosterone. GO:1903874 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1903874 GO:1903873 negative regulation of DNA recombinase mediator complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903873 down regulation of DNA recombinase mediator complex assembly|down-regulation of DNA recombinase mediator complex formation|negative regulation of DNA recombinase mediator complex formation|downregulation of DNA recombinase mediator complex assembly|downregulation of DNA recombinase mediator complex formation|down-regulation of DNA recombinase mediator complex assembly|down regulation of DNA recombinase mediator complex formation|inhibition of DNA recombinase mediator complex formation|inhibition of DNA recombinase mediator complex assembly Any process that stops, prevents or reduces the frequency, rate or extent of DNA recombinase mediator complex assembly. GO:1903872 regulation of DNA recombinase mediator complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903872 regulation of DNA recombinase mediator complex formation Any process that modulates the frequency, rate or extent of DNA recombinase mediator complex assembly. GO:1903871 DNA recombinase mediator complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903871 DNA recombinase mediator complex formation The aggregation, arrangement and bonding together of a set of components to form a DNA recombinase mediator complex. GO:0034043 5-hydroxymethyluracil DNA N-glycosylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034043 5-hmU DNA N-glycosylase activity Catalysis of the removal of 5-hydroxymethyluracil bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar. GO:0010098 suspensor development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010098 The process whose specific outcome is the progression of the suspensor over time, from its formation to the mature structure. The suspensor is the extension at the base of the embryo that anchors the embryo in the embryo sac and pushes it into the endosperm. GO:1903881 regulation of interleukin-17-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903881 regulation of IL-17-mediated signalling pathway|regulation of IL-17-mediated signaling pathway|regulation of interleukin-17-mediated signalling pathway Any process that modulates the frequency, rate or extent of interleukin-17-mediated signaling pathway. GO:0034042 5-formyluracil DNA N-glycosylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034042 5-foU DNA N-glycosylase activity Catalysis of the removal of 5-formyluracil bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar. GO:1903880 17alpha-hydroxyprogesterone binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1903880 Interacting selectively and non-covalently with 17alpha-hydroxyprogesterone. GO:0010097 specification of stamen identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010097 The process in which a floral organ primordium acquires stamen or staminode identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized. GO:0034041 ABC-type sterol transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034041 ATPase-coupled sterol transmembrane transporter activity|sterol-transporting ATPase activity|ATP-coupled sterol transmembrane transporter activity|ATP-dependent sterol transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + sterol(in) = ADP + phosphate + sterol(out). GO:0010099 regulation of photomorphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010099 Any process that modulates the rate or extent of photomorphogenesis. GO:0034040 ATPase-coupled lipid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034040 lipid-transporting ATPase activity|ATP-dependent lipid transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + lipid(in) = ADP + phosphate + lipid(out). GO:0097648 G protein-coupled receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097648 G-protein coupled receptor complex A protein complex that contains G protein-coupled receptors. GO:0010090 trichome morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010090 trichome cell morphogenesis during differentiation The process in which the structures of a hair cell (trichome) cell are generated and organized. This process occurs while the initially relatively unspecialized epidermal cell is acquiring the specialized features of a hair cell. An example of this process is found in Arabidopsis thaliana. GO:0097647 amylin receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097647 amilyn receptor signalling pathway A series of molecular signals initiated by an extracellular amylin combining with a dimeric amylin receptor on the surface of the target cell. GO:0010092 specification of animal organ identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010092 The regionalization process in which the identity of an animal organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized. GO:0034049 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0034049 GO:0097649 A axonemal microtubule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097649 A tubule A complete microtubule with 13 protofilaments that fuses with an incomplete microtubule called B tubule (containing 10 protofilaments only) to form an axonemal outer doublet. Inner and outer dynein arms, as well as the radial spoke, are attached to the A tubule. GO:0010091 trichome branching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010091 Any process involved in the formation of branches in plant hair cells. An example of this process is found in Arabidopsis thaliana. GO:0034048 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0034048 GO:0097644 calcitonin family binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097644 Interacting selectively and non-covalently with any member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)). GO:0010094 specification of carpel identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010094 The process in which a floral organ primordium acquires the carpel identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized. GO:0034047 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0034047 GO:0097643 amylin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097643 Combining with amylin to initiate a change in cell activity. GO:0034046 poly(G) binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034046 poly(rG) binding|poly(G) binding, within an RNA molecule Interacting selectively and non-covalently with a sequence of guanine residues in an RNA molecule. GO:0010093 specification of floral organ identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010093 The process in which the identity of a floral organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized. GO:0097646 calcitonin family receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097646 calcitonin family receptor signalling pathway A series of molecular signals initiated by an extracellular member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)) combining with a calcitonin family receptor on the surface of the target cell. Calcitonin family receptors may form dimers, trimers or tetramers; adrenomedullin and amylin receptors have only been observed as dimers so far. GO:0034045 phagophore assembly site membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034045 PAS membrane|phagophore|pre-autophagosomal structure membrane|isolation membrane A cellular membrane associated with the phagophore assembly site. GO:0010096 specification of sepal identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010096 The process in which a floral organ primordium acquires sepal identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized. GO:0097645 amylin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097645 Interacting selectively and non-covalently with amylin. GO:0010095 specification of petal identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010095 The process in which a floral organ primordium acquires petal identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized. GO:0034044 exomer complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034044 A protein complex that forms a coat structure on vesicles involved in exocytosis of proteins from the trans-Golgi network to the cell surface; in Saccharomyces, the complex contains Chs5p, Chs6p, and Chs6p paralogues. GO:1903889 negative regulation of plant epidermal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903889 down-regulation of plant epidermal cell differentiation|downregulation of plant epidermal cell differentiation|down regulation of plant epidermal cell differentiation|inhibition of plant epidermal cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of plant epidermal cell differentiation. GO:1903888 regulation of plant epidermal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903888 Any process that modulates the frequency, rate or extent of plant epidermal cell differentiation. GO:1903887 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1903887 GO:1903886 positive regulation of chemokine (C-C motif) ligand 20 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903886 activation of CCL20 production|up-regulation of chemokine (C-C motif) ligand 20 production|activation of chemokine (C-C motif) ligand 20 production|upregulation of CCL-20 production|upregulation of C-C motif chemokine 20 production|positive regulation of CCL20 production|up regulation of CCL20 production|up regulation of C-C motif chemokine 20 production|up regulation of CCL-20 production|positive regulation of CCL-20 production|up regulation of chemokine (C-C motif) ligand 20 production|activation of C-C motif chemokine 20 production|positive regulation of C-C motif chemokine 20 production|activation of CCL-20 production|upregulation of CCL20 production|upregulation of chemokine (C-C motif) ligand 20 production|up-regulation of CCL-20 production|up-regulation of C-C motif chemokine 20 production|up-regulation of CCL20 production Any process that activates or increases the frequency, rate or extent of chemokine (C-C motif) ligand 20 production. GO:1903885 negative regulation of chemokine (C-C motif) ligand 20 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903885 down-regulation of CCL20 production|negative regulation of CCL20 production|down regulation of CCL-20 production|down regulation of C-C motif chemokine 20 production|down-regulation of chemokine (C-C motif) ligand 20 production|downregulation of CCL-20 production|downregulation of C-C motif chemokine 20 production|downregulation of CCL20 production|down regulation of CCL20 production|inhibition of CCL20 production|downregulation of chemokine (C-C motif) ligand 20 production|down-regulation of C-C motif chemokine 20 production|negative regulation of CCL-20 production|down-regulation of CCL-20 production|negative regulation of C-C motif chemokine 20 production|down regulation of chemokine (C-C motif) ligand 20 production|inhibition of chemokine (C-C motif) ligand 20 production|inhibition of CCL-20 production|inhibition of C-C motif chemokine 20 production Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-C motif) ligand 20 production. GO:1903884 regulation of chemokine (C-C motif) ligand 20 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903884 regulation of C-C motif chemokine 20 production|regulation of CCL-20 production|regulation of CCL20 production Any process that modulates the frequency, rate or extent of chemokine (C-C motif) ligand 20 production. GO:0009079 pyruvate family amino acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009079 pyruvate family amino acid anabolism|pyruvate family amino acid synthesis|pyruvate family amino acid formation|pyruvate family amino acid biosynthesis The chemical reactions and pathways resulting in the formation of any amino acid that requires pyruvate for its synthesis, e.g. alanine. GO:0009078 pyruvate family amino acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009078 pyruvate family amino acid metabolism The chemical reactions and pathways involving any amino acid that requires pyruvate for its synthesis, e.g. alanine. GO:1903883 positive regulation of interleukin-17-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903883 upregulation of interleukin-17-mediated signaling pathway|upregulation of IL-17-mediated signalling pathway|positive regulation of IL-17-mediated signaling pathway|positive regulation of interleukin-17-mediated signalling pathway|up regulation of IL-17-mediated signaling pathway|up regulation of interleukin-17-mediated signalling pathway|up regulation of interleukin-17-mediated signaling pathway|activation of interleukin-17-mediated signaling pathway|up regulation of IL-17-mediated signalling pathway|activation of IL-17-mediated signalling pathway|positive regulation of IL-17-mediated signalling pathway|upregulation of IL-17-mediated signaling pathway|upregulation of interleukin-17-mediated signalling pathway|up-regulation of interleukin-17-mediated signaling pathway|up-regulation of IL-17-mediated signalling pathway|activation of IL-17-mediated signaling pathway|up-regulation of IL-17-mediated signaling pathway|up-regulation of interleukin-17-mediated signalling pathway|activation of interleukin-17-mediated signalling pathway Any process that activates or increases the frequency, rate or extent of interleukin-17-mediated signaling pathway. GO:0009077 obsolete histidine family amino acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009077 histidine family amino acid degradation|histidine family amino acid breakdown|histidine family amino acid catabolic process|histidine family amino acid catabolism OBSOLETE. The chemical reactions and pathways resulting in the breakdown of amino acids of the histidine family. GO:1903882 negative regulation of interleukin-17-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903882 negative regulation of IL-17-mediated signaling pathway|down-regulation of IL-17-mediated signaling pathway|down-regulation of interleukin-17-mediated signalling pathway|negative regulation of interleukin-17-mediated signalling pathway|down regulation of interleukin-17-mediated signaling pathway|down regulation of IL-17-mediated signalling pathway|downregulation of interleukin-17-mediated signaling pathway|downregulation of IL-17-mediated signalling pathway|downregulation of IL-17-mediated signaling pathway|downregulation of interleukin-17-mediated signalling pathway|down regulation of IL-17-mediated signaling pathway|down regulation of interleukin-17-mediated signalling pathway|down-regulation of interleukin-17-mediated signaling pathway|inhibition of IL-17-mediated signaling pathway|down-regulation of IL-17-mediated signalling pathway|negative regulation of IL-17-mediated signalling pathway|inhibition of interleukin-17-mediated signalling pathway|inhibition of interleukin-17-mediated signaling pathway|inhibition of IL-17-mediated signalling pathway Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-17-mediated signaling pathway. GO:1903892 negative regulation of ATF6-mediated unfolded protein response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903892 inhibition of UPR signaling by ATF6 stress sensor|inhibition of ATF6 branch of UPR|negative regulation of ATF6-alpha UPR branch|down regulation of activating transcription factor 6 signaling in unfolded protein response|down-regulation of ATF6-alpha UPR branch|inhibition of activating transcription factor 6 signaling in unfolded protein response|down-regulation of ATF6 signaling in response to endoplasmic reticulum stress|negative regulation of ATF6 signaling in response to endoplasmic reticulum stress|inhibition of ATF6-mediated unfolded protein response|negative regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling|down-regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling|down-regulation of ATF6-beta UPR branch|negative regulation of ATF6-beta UPR branch|downregulation of ATF6 signaling in response to endoplasmic reticulum stress|down regulation of UPR signaling by ATF6 stress sensor|inhibition of ATF6-alpha UPR branch|inhibition of endoplasmic reticulum unfolded protein response; ATF6 signaling|down regulation of ATF6 signaling in response to endoplasmic reticulum stress|downregulation of UPR signaling by ATF6 stress sensor|down-regulation of ATF6 branch of UPR|negative regulation of ATF6 branch of UPR|down regulation of ATF6-mediated unfolded protein response|downregulation of ATF6-beta UPR branch|down regulation of ATF6-alpha UPR branch|down-regulation of activating transcription factor 6 signaling in unfolded protein response|negative regulation of activating transcription factor 6 signaling in unfolded protein response|downregulation of ATF6-mediated unfolded protein response|inhibition of ATF6 signaling in response to endoplasmic reticulum stress|down regulation of ATF6-beta UPR branch|downregulation of ATF6-alpha UPR branch|down-regulation of UPR signaling by ATF6 stress sensor|negative regulation of UPR signaling by ATF6 stress sensor|down regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling|downregulation of ATF6 branch of UPR|downregulation of activating transcription factor 6 signaling in unfolded protein response|downregulation of endoplasmic reticulum unfolded protein response; ATF6 signaling|down regulation of ATF6 branch of UPR|inhibition of ATF6-beta UPR branch|down-regulation of ATF6-mediated unfolded protein response Any process that stops, prevents or reduces the frequency, rate or extent of the ATF6-mediated unfolded protein response. GO:0009087 methionine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009087 UM-BBD_pathwayID:met methionine catabolism|methionine degradation|methionine breakdown The chemical reactions and pathways resulting in the breakdown of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins. GO:0010065 primary meristem tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010065 primary meristem histogenesis The process whose specific outcome is the progression of the primary meristem over time, from formation to the mature structure, as it occurs during plant embryogenesis. The primary meristem tissue is the protoderm, ground meristem and procambium. GO:0034032 purine nucleoside bisphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034032 purine nucleoside bisphosphate metabolism The chemical reactions and pathways involving a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar. GO:1903891 regulation of ATF6-mediated unfolded protein response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903891 regulation of ATF6 signaling in response to endoplasmic reticulum stress|regulation of UPR signaling by ATF6 stress sensor|regulation of ATF6 signal transduction pathway|regulation of ATF6-beta UPR branch|regulation of ATF6-alpha UPR branch|regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling|regulation of ATF6 branch of UPR|regulation of activating transcription factor 6 signaling in unfolded protein response Any process that modulates the frequency, rate or extent of the ATF6-mediated unfolded protein response. GO:0009086 methionine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009086 methionine biosynthesis|methionine anabolism|methionine synthesis|methionine formation The chemical reactions and pathways resulting in the formation of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins. GO:0010064 embryonic shoot morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010064 primary shoot system morphogenesis The process in which the anatomical structures of embryonic shoot are generated and organized. GO:0034031 ribonucleoside bisphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034031 ribonucleoside bisphosphate degradation|ribonucleoside bisphosphate breakdown|ribonucleoside bisphosphate catabolism The chemical reactions and pathways resulting in the breakdown of a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar. GO:1903890 positive regulation of plant epidermal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903890 up-regulation of plant epidermal cell differentiation|activation of plant epidermal cell differentiation|up regulation of plant epidermal cell differentiation|upregulation of plant epidermal cell differentiation Any process that activates or increases the frequency, rate or extent of plant epidermal cell differentiation. GO:0034030 ribonucleoside bisphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034030 ribonucleoside bisphosphate anabolism|ribonucleoside bisphosphate synthesis|ribonucleoside bisphosphate biosynthesis|ribonucleoside bisphosphate formation The chemical reactions and pathways resulting in the formation of a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar. GO:0009085 lysine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009085 MetaCyc:PWY-5097 lysine synthesis|lysine formation|lysine anabolism|lysine biosynthesis The chemical reactions and pathways resulting in the formation of lysine, 2,6-diaminohexanoic acid. GO:0010067 procambium histogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010067 The formation of the primary meristem or meristematic tissue that gives rise to the primary vascular tissue. GO:0009084 glutamine family amino acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009084 glutamine family amino acid anabolism|glutamine family amino acid biosynthesis|glutamine family amino acid synthesis|glutamine family amino acid formation The chemical reactions and pathways resulting in the formation of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline. GO:0010066 ground meristem histogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010066 The formation of the primary meristem or meristematic tissue that gives rise to the ground tissues. GO:0009083 branched-chain amino acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009083 branched chain family amino acid catabolic process|branched chain family amino acid degradation|branched chain family amino acid breakdown|branched chain family amino acid catabolism The chemical reactions and pathways resulting in the breakdown of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine. GO:0097619 PTEX complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097619 Plasmodium translocon of exported proteins A protein complex that acts as a protein trafficking machinery and is responsible for the export of proteins across the parasitophorous (symbiont-containing) vacuolar membrane and into the human host cell. The PTEX complex is located in the vacuole membrane. It is ATP-powered, and comprises heat shock protein 101 (HSP101; a ClpA/B-like ATPase from the AAA+ superfamily, of a type commonly associated with protein translocons), a parasite protein termed PTEX150, and exported protein 2 (EXP2). EXP2 is the potential channel, as it is the membrane-associated component of the core PTEX complex. Two other proteins, PTEX88 and thioredoxin 2 (TRX2), were also identified as PTEX components. GO:0010069 zygote asymmetric cytokinesis in embryo sac biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010069 The division of the zygote in a plane perpendicular to the long axis of the embryo sac to produce a larger basal cell near the micropyle and a small terminal cell close to what was the central cell and is now the developing endosperm. An example of this process is found in Arabidopsis thaliana. GO:0009082 branched-chain amino acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009082 branched chain family amino acid biosynthesis|branched chain family amino acid formation|branched chain family amino acid biosynthetic process|branched chain family amino acid anabolism|branched chain family amino acid synthesis The chemical reactions and pathways resulting in the formation of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine. GO:0097618 dinoflagellate sulcal notch biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097618 sulcal notch|dinoflagellate sulcus notch A dinoflagellate sulcus that extends all the way to the posterior end of the cell (also known as antapex). The presence of a sulcal notch makes the dinoflagellate hypocone appear bilobed. GO:0010068 protoderm histogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010068 The formation of the primary meristem or meristematic tissue that gives rise to the epidermis. GO:0009081 branched-chain amino acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009081 branched chain family amino acid metabolism The chemical reactions and pathways involving amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine. GO:0009080 pyruvate family amino acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009080 pyruvate family amino acid catabolism|pyruvate family amino acid degradation|pyruvate family amino acid breakdown The chemical reactions and pathways resulting in the breakdown of any amino acid that requires pyruvate for its synthesis, e.g. alanine. SO:0000613 bacterial_RNApol_promoter biolink:SequenceFeature go-plus http://purl.obolibrary.org/obo/SO_0000613 bacterial RNApol promoter A DNA sequence to which bacterial RNA polymerase binds, to begin transcription. GO:0097615 modulation by host of symbiont type IV pilus-dependent motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097615 modulation by host of bacterial type IV pilus-dependent motility The process in which an organism effects a change in the type IV pilus-dependent motility of a symbiont organism (i.e. the controlled movement of a bacterial cell which is dependent on the presence of type IV pili, and which includes social gliding motility and twitching motility). The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0097614 dinoflagellate hypocone biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097614 hypocone|hyposome|hypotheca The part of a dinoflagellate cell below the cingulum; also referred to as the posterior portion of a dinoflagellate cell. It is separated from the epicone by the cingulum. GO:0034039 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034039 8-oxoG DNA N-glycosylase activity Catalysis of the removal of 8-oxo-7,8-dihydroguanine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar. GO:0097617 annealing activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097617 Reactome:R-HSA-5686642 renaturation A nucleic acid binding activity that brings together complementary sequences of nucleic acids so that they pair by hydrogen bonds to form a double-stranded polynucleotide. GO:0034038 deoxyhypusine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034038 RHEA:33299|MetaCyc:2.5.1.46-RXN|Reactome:R-HSA-204617|Reactome:R-HSA-204647|EC:2.5.1.46 eIF5A-precursor-lysine:spermidine 4-aminobutyltransferase (propane-1,3-diamine-forming) activity|spermidine:eIF5A-lysine 4-aminobutyltransferase (propane-1,3-diamine-forming) activity|eIF-5A-deoxyhypusine synthase activity Catalysis of the reaction: [eIF5A-precursor]-lysine + spermidine = [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine. Four sub-reactions have been identified,in which the intermediates remain tightly associated with the enzyme: spermidine + NAD+ = dehydrospermidine + NADH; dehydrospermidine + [enzyme]-lysine = N-(4-aminobutylidene)-[enzyme]-lysine + propane-1,3-diamine; N-(4-aminobutylidene)-[enzyme]-lysine + [eIF5A-precursor]-lysine = N-(4-aminobutylidene)-[eIF5A-precursor]-lysine + [enzyme]-lysine; N-(4-aminobutylidene)-[eIF5A-precursor]-lysine + NADH + H+ = [eIF5A-precursor]-deoxyhypusine + NAD+. GO:0097616 positive regulation by host of symbiont type IV pilus-dependent motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097616 positive regulation by host of bacterial type IV pilus-dependent motility Any process in which an organism activates, maintains or increases the frequency, rate or extent of the type IV pilus-dependent motility of a symbiont organism (i.e. the controlled movement of a bacterial cell which is dependent on the presence of type IV pili, and which includes social gliding motility and twitching motility). The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0034037 purine ribonucleoside bisphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034037 purine ribonucleoside bisphosphate catabolism|purine ribonucleoside bisphosphate degradation|purine ribonucleoside bisphosphate breakdown The chemical reactions and pathways resulting in the breakdown of a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar. GO:0097611 dinoflagellate cingulum biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097611 cingulum|transverse groove|girdle A cell surface furrow that wraps around a dinoflagellate cell; the transverse flagellum lies in it. GO:0034036 purine ribonucleoside bisphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034036 purine ribonucleoside bisphosphate anabolism|purine ribonucleoside bisphosphate synthesis|purine ribonucleoside bisphosphate formation|purine ribonucleoside bisphosphate biosynthesis The chemical reactions and pathways resulting in the formation of a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar. GO:0010061 regulation of trichoblast fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010061 Any process that modulates trichoblast fate specification. GO:0097610 cell surface furrow biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097610 cell surface groove|groove|furrow A furrow that may be found on the cell surface. Examples include the cingulum and sulcus found in some dinoflagellates. GO:0010060 negative regulation of atrichoblast fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010060 down-regulation of atrichoblast fate|inhibition of atrichoblast fate|down regulation of atrichoblast fate|downregulation of atrichoblast fate Any process that suppresses atrichoblast fate specification. GO:0034035 purine ribonucleoside bisphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034035 purine ribonucleoside bisphosphate metabolism The chemical reactions and pathways involving a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar. GO:0034034 purine nucleoside bisphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034034 purine nucleoside bisphosphate catabolism|purine nucleoside bisphosphate degradation|purine nucleoside bisphosphate breakdown The chemical reactions and pathways resulting in the breakdown of a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar. GO:0010063 positive regulation of trichoblast fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010063 stimulation of trichoblast fate|up-regulation of trichoblast fate|activation of trichoblast fate|up regulation of trichoblast fate|upregulation of trichoblast fate Any process that induces or promotes trichoblast fate specification. GO:0097613 dinoflagellate epicone biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097613 epicone|episome|epitheca The part of a dinoflagellate cell above the cingulum; also referred to as the anterior portion of a dinoflagellate cell. It is separated from the hypocone by the cingulum. GO:0097612 dinoflagellate sulcus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097612 longitudinal groove|sulcus|longitudinal furrow A cell surface furrow that occurs on the ventral side of a dinoflagellate cell. It partially houses the longitudinal flagellum. The sulcus intersects with the cingulum on the ventral side of a dinoflagellate cell. GO:0010062 negative regulation of trichoblast fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010062 down-regulation of trichoblast fate|downregulation of trichoblast fate|down regulation of trichoblast fate|inhibition of trichoblast fate Any process that suppresses trichoblast fate specification. GO:0034033 purine nucleoside bisphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034033 purine nucleoside bisphosphate anabolism|purine nucleoside bisphosphate synthesis|purine nucleoside bisphosphate formation|purine nucleoside bisphosphate biosynthesis The chemical reactions and pathways resulting in the formation of a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar. GO:0097620 (R)-mandelate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097620 RHEA:43112 D-mandelate dehydrogenase activity Catalysis of the reaction: (R)-2-hydroxy-2-phenylacetate + acceptor = phenylglyoxylate + reduced acceptor. PO:0025594 ground meristem biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025594 A portion of meristem tissue (PO:0009013) that gives rise to a portion of ground tissue (PO:0025059). GO:1903899 positive regulation of PERK-mediated unfolded protein response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903899 up regulation of PERK signaling in response to endoplasmic reticulum stress|upregulation of UPR signaling by PERK stress sensor|up-regulation of PERK branch of UPR|activation of PERK branch of UPR|activation of PKR-like ER kinase signal transduction|up-regulation of PKR-like ER kinase signal transduction|up-regulation of endoplasmic reticulum unfolded protein response; PERK signaling|up regulation of PERK-mediated unfolded protein response|activation of PERK-mediated unfolded protein response|positive regulation of EIF2AK3-mediated unfolded protein response|upregulation of PERK signaling in response to endoplasmic reticulum stress|up regulation of UPR signaling by PERK stress sensor|activation of UPR signaling by PERK stress sensor|positive regulation of PERK branch of UPR|positive regulation of UPR signaling by PERK stress sensor|positive regulation of PKR-like ER kinase signal transduction|upregulation of endoplasmic reticulum unfolded protein response; PERK signaling|up regulation of PERK branch of UPR|up regulation of PKR-like ER kinase signal transduction|up-regulation of PERK signaling in response to endoplasmic reticulum stress|up-regulation of PERK-mediated unfolded protein response|up regulation of endoplasmic reticulum unfolded protein response; PERK signaling|up-regulation of UPR signaling by PERK stress sensor|activation of PERK signaling in response to endoplasmic reticulum stress|upregulation of PERK branch of UPR|activation of endoplasmic reticulum unfolded protein response; PERK signaling|positive regulation of endoplasmic reticulum unfolded protein response; PERK signaling|upregulation of PKR-like ER kinase signal transduction|upregulation of PERK-mediated unfolded protein response|positive regulation of PERK signaling in response to endoplasmic reticulum stress Any process that activates or increases the frequency, rate or extent of the PERK-mediated unfolded protein response. GO:1903898 negative regulation of PERK-mediated unfolded protein response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903898 down regulation of PERK-mediated unfolded protein response|downregulation of PERK signaling in response to endoplasmic reticulum stress|downregulation of PERK-mediated unfolded protein response|negative regulation of EIF2AK3-mediated unfolded protein response|down regulation of UPR signaling by PERK stress sensor|inhibition of endoplasmic reticulum unfolded protein response; PERK signaling|down regulation of PERK signaling in response to endoplasmic reticulum stress|downregulation of UPR signaling by PERK stress sensor|down-regulation of PERK branch of UPR|negative regulation of PERK branch of UPR|down-regulation of PKR-like ER kinase signal transduction|negative regulation of PKR-like ER kinase signal transduction|down-regulation of PERK-mediated unfolded protein response|inhibition of PERK signaling in response to endoplasmic reticulum stress|down regulation of endoplasmic reticulum unfolded protein response; PERK signaling|down-regulation of UPR signaling by PERK stress sensor|negative regulation of UPR signaling by PERK stress sensor|downregulation of PERK branch of UPR|inhibition of PERK-mediated unfolded protein response|downregulation of PKR-like ER kinase signal transduction|downregulation of endoplasmic reticulum unfolded protein response; PERK signaling|down regulation of PERK branch of UPR|down regulation of PKR-like ER kinase signal transduction|inhibition of UPR signaling by PERK stress sensor|inhibition of PERK branch of UPR|inhibition of PKR-like ER kinase signal transduction|negative regulation of PERK signaling in response to endoplasmic reticulum stress|down-regulation of PERK signaling in response to endoplasmic reticulum stress|negative regulation of endoplasmic reticulum unfolded protein response; PERK signaling|down-regulation of endoplasmic reticulum unfolded protein response; PERK signaling Any process that stops, prevents or reduces the frequency, rate or extent of the PERK-mediated unfolded protein response. GO:1903897 regulation of PERK-mediated unfolded protein response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903897 regulation of PERK signaling in response to endoplasmic reticulum stress|regulation of UPR signaling by PERK stress sensor|regulation of PERK signal transduction pathway|regulation of EIF2AK3-mediated unfolded protein response|regulation of endoplasmic reticulum unfolded protein response; PERK signaling|regulation of PERK branch of UPR|regulation of PKR-like ER kinase signal transduction Any process that modulates the frequency, rate or extent of the PERK-mediated unfolded protein response. GO:1903896 positive regulation of IRE1-mediated unfolded protein response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903896 up-regulation of IRE1p unfolded protein response|upregulation of IRE1-mediated unfolded protein response|upregulation of inositol-requiring transmembrane kinase/endonuclease signal transduction|upregulation of IRE1 signaling in response to endoplasmic reticulum stress|up regulation of UPR signaling by IRE1 stress sensor|activation of UPR signaling by IRE1 stress sensor|up regulation of IRE1alpha unfolded protein response|positive regulation of IRE1 branch of UPR|positive regulation of UPR signaling by IRE1 stress sensor|upregulation of endoplasmic reticulum unfolded protein response; IRE1 signaling|positive regulation of IRE1alpha unfolded protein response|up regulation of IRE1 branch of UPR|upregulation of IRE1p unfolded protein response|up-regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction|up-regulation of IRE1 signaling in response to endoplasmic reticulum stress|activation of IRE1alpha unfolded protein response|up regulation of IRE1-mediated unfolded protein response|activation of IRE1-mediated unfolded protein response|up-regulation of UPR signaling by IRE1 stress sensor|up regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling|activation of IRE1 signaling in response to endoplasmic reticulum stress|upregulation of IRE1 branch of UPR|activation of inositol-requiring transmembrane kinase/endonuclease signal transduction|activation of endoplasmic reticulum unfolded protein response; IRE1 signaling|positive regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling|up-regulation of IRE1alpha unfolded protein response|up regulation of IRE1p unfolded protein response|positive regulation of IRE1p unfolded protein response|positive regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction|positive regulation of IRE1 signaling in response to endoplasmic reticulum stress|up regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction|up regulation of IRE1 signaling in response to endoplasmic reticulum stress|up-regulation of IRE1-mediated unfolded protein response|upregulation of UPR signaling by IRE1 stress sensor|positive regulation of ERN1-mediated unfolded protein response|up-regulation of IRE1 branch of UPR|activation of IRE1p unfolded protein response|upregulation of IRE1alpha unfolded protein response|activation of IRE1 branch of UPR|up-regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling Any process that activates or increases the frequency, rate or extent of the IRE1-mediated unfolded protein response. GO:1903895 negative regulation of IRE1-mediated unfolded protein response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903895 down regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction|down regulation of IRE1 signaling in response to endoplasmic reticulum stress|downregulation of UPR signaling by IRE1 stress sensor|negative regulation of IRE1 branch of UPR|downregulation of IRE1alpha unfolded protein response|down-regulation of IRE1 branch of UPR|inhibition of IRE1p unfolded protein response|down regulation of IRE1-mediated unfolded protein response|inhibition of inositol-requiring transmembrane kinase/endonuclease signal transduction|inhibition of IRE1 signaling in response to endoplasmic reticulum stress|negative regulation of UPR signaling by IRE1 stress sensor|down-regulation of UPR signaling by IRE1 stress sensor|downregulation of IRE1-mediated unfolded protein response|down regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling|negative regulation of IRE1alpha unfolded protein response|downregulation of IRE1 branch of UPR|down-regulation of IRE1alpha unfolded protein response|down regulation of IRE1p unfolded protein response|downregulation of endoplasmic reticulum unfolded protein response; IRE1 signaling|down regulation of IRE1 branch of UPR|inhibition of IRE1 branch of UPR|inhibition of UPR signaling by IRE1 stress sensor|downregulation of IRE1p unfolded protein response|negative regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction|down-regulation of IRE1-mediated unfolded protein response|down-regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction|down-regulation of IRE1 signaling in response to endoplasmic reticulum stress|negative regulation of IRE1 signaling in response to endoplasmic reticulum stress|negative regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling|inhibition of IRE1alpha unfolded protein response|down-regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling|inhibition of IRE1-mediated unfolded protein response|negative regulation of IRE1p unfolded protein response|down-regulation of IRE1p unfolded protein response|downregulation of inositol-requiring transmembrane kinase/endonuclease signal transduction|downregulation of IRE1 signaling in response to endoplasmic reticulum stress|down regulation of UPR signaling by IRE1 stress sensor|inhibition of endoplasmic reticulum unfolded protein response; IRE1 signaling|down regulation of IRE1alpha unfolded protein response|negative regulation of ERN1-mediated unfolded protein response Any process that stops, prevents or reduces the frequency, rate or extent of the IRE1-mediated unfolded protein response. GO:1903894 regulation of IRE1-mediated unfolded protein response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903894 regulation of IRE1alpha unfolded protein response|regulation of IRE1 signal transduction pathway|regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling|regulation of IRE1 branch of UPR|regulation of IRE1p unfolded protein response|regulation of ERN1-mediated unfolded protein response|regulation of IRE1 signaling in response to endoplasmic reticulum stress|regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction|regulation of UPR signaling by IRE1 stress sensor Any process that modulates the frequency, rate or extent of the IRE1-mediated unfolded protein response. GO:0009089 lysine biosynthetic process via diaminopimelate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009089 lysine anabolism via diaminopimelate|lysine synthesis via diaminopimelate|diaminopimelic acid pathway|lysine formation via diaminopimelate|lysine biosynthesis via diaminopimelic acid|lysine biosynthetic process via diaminopimelic acid|diaminopimelate pathway The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate. GO:0009088 threonine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009088 MetaCyc:HOMOSER-THRESYN-PWY|MetaCyc:THRESYN-PWY threonine anabolism|threonine biosynthesis|threonine synthesis|threonine formation The chemical reactions and pathways resulting in the formation of threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins. GO:1903893 positive regulation of ATF6-mediated unfolded protein response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903893 up-regulation of UPR signaling by ATF6 stress sensor|up regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling|activation of ATF6-alpha UPR branch|upregulation of ATF6 branch of UPR|activation of endoplasmic reticulum unfolded protein response; ATF6 signaling|activation of ATF6 signaling in response to endoplasmic reticulum stress|up-regulation of ATF6-beta UPR branch|positive regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling|upregulation of activating transcription factor 6 signaling in unfolded protein response|up-regulation of ATF6-mediated unfolded protein response|positive regulation of ATF6 signaling in response to endoplasmic reticulum stress|up-regulation of ATF6-alpha UPR branch|activation of ATF6-beta UPR branch|up regulation of ATF6 signaling in response to endoplasmic reticulum stress|upregulation of UPR signaling by ATF6 stress sensor|activation of ATF6 branch of UPR|up-regulation of ATF6 branch of UPR|activation of activating transcription factor 6 signaling in unfolded protein response|up-regulation of activating transcription factor 6 signaling in unfolded protein response|positive regulation of ATF6-beta UPR branch|up-regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling|upregulation of ATF6-mediated unfolded protein response|upregulation of ATF6-alpha UPR branch|up regulation of ATF6-beta UPR branch|upregulation of ATF6 signaling in response to endoplasmic reticulum stress|up regulation of UPR signaling by ATF6 stress sensor|activation of UPR signaling by ATF6 stress sensor|positive regulation of ATF6 branch of UPR|positive regulation of UPR signaling by ATF6 stress sensor|upregulation of endoplasmic reticulum unfolded protein response; ATF6 signaling|up regulation of ATF6 branch of UPR|positive regulation of activating transcription factor 6 signaling in unfolded protein response|up regulation of ATF6-mediated unfolded protein response|upregulation of ATF6-beta UPR branch|activation of ATF6-mediated unfolded protein response|up regulation of ATF6-alpha UPR branch|up regulation of activating transcription factor 6 signaling in unfolded protein response|up-regulation of ATF6 signaling in response to endoplasmic reticulum stress|positive regulation of ATF6-alpha UPR branch Any process that activates or increases the frequency, rate or extent of the ATF6-mediated unfolded protein response. GO:0034021 response to silicon dioxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034021 response to silox|response to silica Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silicon dioxide stimulus. GO:0009098 leucine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009098 MetaCyc:LEUSYN-PWY leucine biosynthesis|leucine anabolism|leucine synthesis|leucine formation The chemical reactions and pathways resulting in the formation of leucine, 2-amino-4-methylpentanoic acid. GO:0010076 maintenance of floral meristem identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010076 The process in which an organism retains a population of floral meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate. GO:0034020 neoxanthin synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034020 EC:5.3.99.9|KEGG_REACTION:R06948|RHEA:10128|MetaCyc:RXN1F-155 violaxanthin-neoxanthin isomerase (epoxide-opening) activity|NSY Catalysis of the reaction: all-trans-violaxanthin = all-trans-neoxanthin. GO:0009097 isoleucine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009097 MetaCyc:ILEUSYN-PWY isoleucine biosynthesis|isoleucine anabolism|isoleucine synthesis|isoleucine formation The chemical reactions and pathways resulting in the formation of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid. GO:0010075 regulation of meristem growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010075 regulation of meristem size Any process involved in maintaining the size and shape of a meristem. GO:0010078 maintenance of root meristem identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010078 The process in which an organism retains a population of root meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate. GO:0009096 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009096 GO:0009095 aromatic amino acid family biosynthetic process, prephenate pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009095 aromatic amino acid family formation, prephenate pathway|aromatic amino acid family biosynthetic process via prephenate(2-)|aromatic amino acid family biosynthetic process via prephenate|aromatic amino acid family anabolism, prephenate pathway|aromatic amino acid family synthesis, prephenate pathway The chemical reactions and pathways resulting in the formation of phenylalanine and tyrosine from other compounds, including chorismate, via the intermediate prephenate. GO:0010077 maintenance of inflorescence meristem identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010077 The process in which an organism retains a population of inflorescence meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate. GO:0009094 L-phenylalanine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009094 L-phenylalanine biosynthesis|phenylalanine biosynthetic process, shikimate pathway|phenylalanine biosynthesis|phenylalanine biosynthetic process|L-phenylalanine anabolism|L-phenylalanine synthesis|L-phenylalanine formation|phenylalanine biosynthetic process, prephenate pathway The chemical reactions and pathways resulting in the formation of L-phenylalanine, the L-enantiomer of 2-amino-3-phenylpropanoic acid, i.e. (2S)-2-amino-3-phenylpropanoic acid. GO:0009093 cysteine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009093 Wikipedia:Cysteine cysteine catabolism|cysteine degradation|cysteine breakdown The chemical reactions and pathways resulting in the breakdown of cysteine, 2-amino-3-mercaptopropanoic acid. GO:0097629 extrinsic component of omegasome membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097629 omegasome peripheral membrane|extrinsic to omegasome membrane The component of the omegasome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:0010079 maintenance of vegetative meristem identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010079 The process in which an organism retains a population of vegetative meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate. GO:0009092 homoserine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009092 homoserine metabolism The chemical reactions and pathways involving homoserine, alpha-amino-gamma-hydroxybutyric acid, an intermediate in the biosynthesis of cystathionine, threonine and methionine. GO:0009091 homoserine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009091 MetaCyc:HOMOCYSDEGR-PWY homoserine degradation|homoserine breakdown|homoserine catabolism The chemical reactions and pathways resulting in the breakdown of homoserine, alpha-amino-gamma-hydroxybutyric acid. GO:0009090 homoserine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009090 MetaCyc:HOMOSERSYN-PWY homoserine synthesis|homoserine formation|homoserine biosynthesis|homoserine anabolism The chemical reactions and pathways resulting in the formation of homoserine, alpha-amino-gamma-hydroxybutyric acid. GO:0097626 low-affinity L-arginine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097626 low affinity L-arginine transmembrane transporter activity Enables the transfer of L-arginine from one side of a membrane to the other. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations. GO:0034029 2-oxoglutarate carboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034029 MetaCyc:RXN-8457|RHEA:20425|EC:6.4.1.7|KEGG_REACTION:R08201 oxalosuccinate synthetase activity|OGC|carboxylating factor for ICDH|CFI Catalysis of the reaction: 2-oxoglutarate + ATP + bicarbonate = ADP + 2 H(+) + oxalosuccinate + phosphate. GO:0097625 low-affinity basic amino acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097625 low affinity basic amino acid transmembrane transporter activity Enables the transfer of basic amino acids from one side of a membrane to the other. Basic amino acids have a pH above 7. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations. GO:0034028 5-(carboxyamino)imidazole ribonucleotide synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034028 EC:6.3.4.18|KEGG_REACTION:R07404|RHEA:19317|MetaCyc:RXN0-742 PurK|5-amino-1-(5-phospho-D-ribosyl)imidazole:carbon-dioxide ligase (ADP-forming) activity|N5-CAIR synthetase activity|N5-carboxyaminoimidazole ribonucleotide synthetase activity Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole + ATP + bicarbonate = 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + 3 H(+) + phosphate. GO:0010070 zygote asymmetric cell division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010070 zygote asymmetric cytokinesis The division of the zygote into two daughter cells that will adopt developmentally distinct potentials. GO:0097628 distal tip cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097628 The orderly movement of a distal tip cell. GO:0034027 (carboxyethyl)arginine beta-lactam-synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034027 MetaCyc:6.3.3.4-RXN|RHEA:23620|KEGG_REACTION:R05467|EC:6.3.3.4 beta-lactam synthetase activity|L-N2-(2-carboxyethyl)arginine cyclo-ligase (AMP-forming) activity|L-2-N-(2-carboxyethyl)arginine cyclo-ligase (AMP-forming) activity Catalysis of the reaction: N(2)-(2-carboxyethyl)-L-arginine + ATP = AMP + deoxyamidinoproclavaminate + diphosphate + 2 H(+). GO:0097627 high-affinity L-ornithine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097627 high affinity L-ornithine transmembrane transporter activity Enables the transfer of L-ornithine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. GO:0034026 L-amino-acid alpha-ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034026 EC:6.3.2.49|RHEA:44332|MetaCyc:6.3.2.28-RXN YwfE|L-amino acid alpha-ligase activity|bacilysin synthetase activity|L-amino acid ligase activity Catalysis of the reaction: ATP + an L-amino acid + an L-amino acid = ADP + phosphate + L-aminoacyl-L-amino acid. GO:0034025 D-aspartate ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034025 MetaCyc:6.3.1.12-RXN|RHEA:10752|EC:6.3.1.12 aslfm|D-aspartate:[beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n ligase (ADP-forming) activity|D-aspartic acid-activating enzyme|UDP-MurNAc-pentapeptide:D-aspartate ligase activity Catalysis of the reaction: ATP + D-aspartate + [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n = [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-6-N-(beta-D-Asp)-L-Lys-D-Ala-D-Ala)]n + ADP + phosphate. GO:0097622 cytoplasmic translational elongation through polyproline stretches biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097622 The successive addition of amino acid residues to a nascent polypeptide chain, proceeding through regions of multiple repeated proline codons, during protein biosynthesis in the cytoplasm. GO:0010072 primary shoot apical meristem specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010072 embryo shoot apical meristem specification The specification of the meristem which will give rise to all post-embryonic above-ground structures of the plant as well as the non-root below-ground structures, such as rhizomes and tubers. GO:0034024 glutamate-putrescine ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034024 MetaCyc:RXN0-3901|RHEA:13633|EC:6.3.1.11|KEGG_REACTION:R07414 gamma-glutamylputrescine synthetase activity|L-glutamate:putrescine ligase (ADP-forming) activity|YcjK Catalysis of the reaction: L-glutamate + ATP + putrescine = gamma-L-glutamylputrescine + ADP + 2 H(+) + phosphate. GO:0097621 monoamine oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097621 RHEA:26414 amine:oxygen oxidoreductase (deaminating) activity Catalysis of the reaction: RCH2NHR' + H2O + O2 = RCHO + R'NH2 + H2O2. GO:0010071 root meristem specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010071 The specification of a meristem which will give rise to a primary or lateral root. GO:0034023 5-(carboxyamino)imidazole ribonucleotide mutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034023 MetaCyc:5.4.99.18-RXN|EC:5.4.99.18|RHEA:13193 PurE|class I PurE|N5-CAIR mutase activity|N5-carboxyaminoimidazole ribonucleotide mutase activity|5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole carboxymutase activity Catalysis of the reaction: 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate. GO:0010074 maintenance of meristem identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010074 meristem cell maintenance|maintenance of meristem cell identity The process in which an organism retains a population of meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate. GO:0097624 UDP-galactose transmembrane import into Golgi lumen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097624 UDP-galactose import into Golgi lumen The directed movement of UDP-galactose into the Golgi lumen across the Golgi membrane. GO:0097623 potassium ion export across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097623 potassium export|potassium export across plasma membrane|potassium ion export from cell|potassium ion export The directed movement of potassium ions from inside of a cell, across the plasma membrane and into the extracellular region. GO:0034022 3-(hydroxyamino)phenol mutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034022 UM-BBD_enzymeID:e0953|MetaCyc:5.4.4.3-RXN|RHEA:20577|KEGG_REACTION:R06988|EC:5.4.4.3 3-hydroxylaminophenol mutase activity|3HAP mutase activity|3-(hydroxyamino)phenol hydroxymutase activity Catalysis of the reaction: 3-hydroxyaminophenol = aminohydroquinone. GO:0010073 meristem maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010073 Any process involved in maintaining the identity, size and shape of a meristem. GO:0097673 SCF-Ucc1 ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097673 SCF-YLR224W ubiquitin ligase complex An SCF ubiquitin ligase complex in which the F-box protein is YLR224W in S. cerevisiae. GO:0097672 SCF-Pof5 ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097672 SCF-YDR306C ubiquitin ligase complex An SCF ubiquitin ligase complex in which the F-box protein is Pof5 in S. pombe (YDR306C in S. cerevisiae). UBERON:0035083 transverse process-bearing vertebra biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035083 pygal vertebra|TP vertebra A vertebra that has a transverse process. GO:0097675 SCF-Hrt3/Pof7 ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097675 An SCF ubiquitin ligase complex in which the F-box protein is Hrt3 in S. cerevisiae (Pof7 in S. pombe). GO:0097674 SCF-YLR352W ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097674 An SCF ubiquitin ligase complex in which the F-box protein is YLR352W in S. cerevisiae. GO:0097671 SCF-YDR131C ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097671 An SCF ubiquitin ligase complex in which the F-box protein is YDR131C in S. cerevisiae. GO:0034019 obsolete capsanthin/capsorubin synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034019 capsanthin-capsorubin synthase activity|CCS|violaxanthin-capsorubin isomerase (ketone-forming) activity|ketoxanthophyll synthase activity|capsanthin/capsorubin synthase activity OBSOLETE. Catalysis of the reactions: violaxanthin = capsorubin, and antheraxanthin = capsanthin. GO:0097670 SCF-Ufo1/Pof10 ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097670 An SCF ubiquitin ligase complex in which the F-box protein is Ufo1 in S. cerevisiae (Pof10 in S. pombe). GO:0009059 macromolecule biosynthetic process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0009059 macromolecule synthesis|macromolecule formation|biopolymer biosynthetic process|macromolecule biosynthesis|macromolecule anabolism The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. GO:0009058 biosynthetic process biolink:BiologicalProcess go-plus goslim_plant|goslim_metagenomics|goslim_generic|goslim_chembl http://purl.obolibrary.org/obo/GO_0009058 Wikipedia:Anabolism formation|anabolism|multicellular organismal biosynthetic process|synthesis|single-organism biosynthetic process|biosynthesis The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones. GO:0009057 macromolecule catabolic process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0009057 biopolymer catabolic process|macromolecule catabolism|macromolecule degradation|macromolecule breakdown|multicellular organismal macromolecule catabolic process The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. GO:0009056 catabolic process biolink:BiologicalProcess go-plus goslim_plant|goslim_generic|goslim_chembl|goslim_agr http://purl.obolibrary.org/obo/GO_0009056 Wikipedia:Catabolism degradation|breakdown|multicellular organismal catabolic process|single-organism catabolic process|catabolism The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism. GO:0009055 electron transfer activity biolink:MolecularActivity go-plus goslim_pir|goslim_metagenomics http://purl.obolibrary.org/obo/GO_0009055 Reactome:R-HSA-2564826|Reactome:R-HSA-169260 electron carrier|electron transporter activity|electron donor activity|electron acceptor activity Any molecular entity that serves as an electron acceptor and electron donor in an electron transport chain. An electron transport chain is a process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient. GO:0034010 sulfolactate sulfo-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034010 EC:4.4.1.24|KEGG_REACTION:R07633|MetaCyc:4.4.1.24-RXN|RHEA:21428 3-sulfolactate bisulfite-lyase activity|3-sulfolactate bisulfite-lyase (pyruvate-forming) activity|SuyAB|Suy Catalysis of the reaction: 3-sulfolactate = pyruvate + sulfite. GO:0009065 glutamine family amino acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009065 glutamine family amino acid degradation|glutamine family amino acid breakdown|glutamine family amino acid catabolism The chemical reactions and pathways resulting in the breakdown of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline. GO:0010043 response to zinc ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010043 response to zinc Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus. GO:0010042 response to manganese ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010042 response to manganese Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus. GO:0009064 glutamine family amino acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009064 glutamine family amino acid metabolism The chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline. GO:0010045 response to nickel cation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010045 response to nickel Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nickel cation stimulus. GO:0009063 cellular amino acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009063 amino acid catabolic process|cellular amino acid degradation|cellular amino acid catabolism|cellular amino acid breakdown The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents. GO:0009062 fatty acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009062 Wikipedia:Fatty_acid_degradation fatty acid catabolism|fatty acid degradation|fatty acid breakdown The chemical reactions and pathways resulting in the breakdown of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes. GO:0010044 response to aluminum ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010044 response to aluminium ion|response to aluminum Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aluminum ion stimulus. GO:0009061 anaerobic respiration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009061 Wikipedia:Anaerobic_respiration|MetaCyc:ANARESP1-PWY|Wikipedia:Cellular_respiration#Anaerobic_respiration The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which uses compounds other than oxygen (e.g. nitrate, sulfate) as the terminal electron acceptor. GO:0010047 fruit dehiscence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010047 The process leading to the spontaneous opening of the fruit permitting the escape of seeds. GO:0010046 response to mycotoxin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010046 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycotoxin stimulus. A mycotoxin is a toxic chemical substance produced by fungi. GO:0009060 aerobic respiration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009060 MetaCyc:PWY-3781|Wikipedia:Cellular_respiration#Aerobic_respiration The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor. GO:0010049 acquisition of plant reproductive competence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010049 acquisition of reproductive competence The process in which a plant acquires the ability to respond to a floral inductive signal. GO:0010048 vernalization response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010048 The process of thermal induction in plants in which flowering is promoted by exposure to low temperatures. GO:0034018 ascopyrone tautomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034018 RHEA:22568|EC:5.3.2.7|MetaCyc:5.3.3.15-RXN ascopyrone P tautomerase activity|APTM|1,5-anhydro-D-glycero-hex-3-en-2-ulose tautomerase activity|1,5-anhydro-D-glycero-hex-3-en-2-ulose delta3-delta1-isomerase activity|ascopyrone isomerase activity|APM tautomerase activity|ascopyrone intramolecular oxidoreductase activity Catalysis of the reaction: 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose = 1,5-anhydro-4-deoxy-D-glycero-hex-1-en-3-ulose. GO:0034017 trans-2-decenoyl-acyl-carrier-protein isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034017 RHEA:23568|EC:5.3.3.14|MetaCyc:5.3.3.14-RXN trans-2, cis-3 decenoyl-ACP isomerase activity|FabM|trans-2,cis-3-decenoyl-ACP isomerase activity|trans-2-cis-3-decenoyl-ACP isomerase activity|decenoyl-acyl-carrier-protein delta2-trans-delta3-cis-isomerase activity|trans-2, cis-3 decenoyl-[acyl-carrier-protein] isomerase activity|trans-2-decenoyl-ACP isomerase activity|beta-hydroxydecanoyl thioester dehydrase activity Catalysis of the reaction: trans-dec-2-enoyl-[acyl-carrier protein] = cis-dec-3-enoyl-[acyl-carrier protein]. GO:0034016 polyenoic fatty acid isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034016 RHEA:14889|EC:5.3.3.13|KEGG_REACTION:R06502|MetaCyc:5.3.3.13-RXN PFI|eicosapentaenoate cis-delta5,8,11,14,17-eicosapentaenoate cis-delta5-trans-delta7,9-cis-delta14,17 isomerase activity|(5Z,8Z,11Z,14Z,17Z)-icosapentaenoate delta8,11-delta7,9-isomerase (trans-double-bond-forming) activity|(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate delta8,11-delta7,8-isomerase activity|(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate delta8,11-delta7,9-isomerase (trans-double-bond-forming) activity Catalysis of the reaction: all-cis-icosa-5,8,11,14,17-pentaenoate = (5Z,7E,9E,14Z,17Z)-icosapentaenoate. GO:0034015 L-ribulose-5-phosphate 3-epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034015 MetaCyc:LXULRU5P-RXN|EC:5.1.3.22|RHEA:18497 L-xylulose 5-phosphate 3-epimerase activity|SgaU|UlaE Catalysis of the reaction: L-ribulose 5-phosphate = L-xylulose 5-phosphate. GO:0097677 STAT family protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097677 signal transducers and activators of transcription family protein binding Interacting selectively and non-covalently with any member of the signal transducers and activators of transcription (STAT) protein family. STATs are, as the name indicates, both signal transducers and transcription factors. STATs are activated by cytokines and some growth factors and thus control important biological processes including cell growth, cell differentiation, apoptosis and immune responses. GO:0034014 response to triglyceride biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034014 response to triacylglyceride|response to triacylglycerol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triglyceride stimulus. GO:0034013 aliphatic aldoxime dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034013 RHEA:11316|EC:4.99.1.5|MetaCyc:4.99.1.5-RXN aliphatic aldoxime hydro-lyase activity|aliphatic aldoxime hydro-lyase (aliphatic-nitrile-forming) activity|OxdA Catalysis of the reaction: an aliphatic aldoxime = an aliphatic nitrile + H2O. GO:0097676 histone H3-K36 dimethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097676 The modification of histone H3 by addition of two methyl groups to lysine at position 36 of the histone. GO:0010041 response to iron(III) ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010041 response to iron(III) Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(III) ion stimulus. GO:0034012 FAD-AMP lyase (cyclizing) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034012 EC:4.6.1.15|RHEA:13729 FAD AMP-lyase (riboflavin-cyclic-4',5'-phosphate-forming) activity|FAD AMP-lyase (cyclic-FMN-forming) activity|FMN cyclase activity Catalysis of the reaction: FAD = AMP + riboflavin cyclic-4',5'-phosphate. GO:0097679 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0097679 GO:0097678 SOCS family protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097678 suppressor of cytokine signaling family protein binding Interacting selectively and non-covalently with any member of the suppressor of cytokine signaling (SOCS) family of proteins. SOCS represent an important mechanism to extinguish cytokine and growth factor receptor signaling. Individual SOCS proteins are typically induced by specific cytokines and growth factors, thereby generating a negative feedback loop. SOCS proteins have important functions in development and homeostasis, and in disease, particularly tumor suppression and anti-inflammatory functions. GO:0034011 L-cysteate sulfo-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034011 KEGG_REACTION:R07634|RHEA:13441|MetaCyc:4.4.1.25-RXN|EC:4.4.1.25 L-cysteate sulfo-lyase (deaminating) activity|L-cysteate bisulfite-lyase (deaminating; pyruvate-forming) activity|CuyA Catalysis of the reaction: L-cysteate + H(2)O = NH(4)(+) + pyruvate + sulfite. GO:0010040 response to iron(II) ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010040 response to iron(II) Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(II) ion stimulus. GO:0097684 dinoflagellate antapex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097684 antapex The anterior most point of a dinoflagellate hypocone. GO:0097683 dinoflagellate apex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097683 apex The anterior most point of a dinoflagellate epicone. UBERON:0035091 extrinsic post-anal tail muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035091 A post-anal tail that attaches outside the tail. GO:0097686 dinoflagellate apical horn biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097686 A horn-shaped dinoflagellate apex found in thecate species. GO:0097685 dinoflagellate apical groove biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097685 apical groove A cell surface furrow (or groove) found on a dinoflagellate apex. It typically loops around the apex. GO:0097680 double-strand break repair via classical nonhomologous end joining biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097680 canonical nonhomologous end joining|C-NHEJ An instance of double-strand break repair via nonhomologous end joining that requires a number of factors important for V(D)J recombination, including the KU70/80 heterodimer (KU), XRCC4, ligase IV, and DNA-PKcs in mammals. It does not produce translocations (as opposed to the alternative nonhomologous end joining). GO:0034009 isoprene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034009 MetaCyc:4.2.3.27-RXN|KEGG_REACTION:R08199|EC:4.2.3.27|RHEA:13369 dimethylallyl-diphosphate diphosphate-lyase (isoprene-forming) activity|ISPC|ISPS Catalysis of the reaction: dimethylallyl diphosphate = diphosphate + isoprene. GO:0097682 intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097682 Enables the transmembrane transfer of cations by a channel that opens when phosphatidylinositol-3,5-bisphosphate has been bound by the channel complex or one of its constituent parts. GO:0034008 R-linalool synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034008 MetaCyc:4.2.3.26-RXN|RHEA:15809|EC:4.2.3.26|KEGG_REACTION:R07632 (3R)-linalool synthase activity|geranyl-diphosphate diphosphate-lyase [(3R)-linalool-forming] activity|(-)-3R-linalool synthase activity Catalysis of the reaction: geranyl diphosphate + H(2)O = (R)-linalool + diphosphate. GO:0097681 double-strand break repair via alternative nonhomologous end joining biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097681 A-NHEJ|MMEJ|alt-NHEJ|double-strand break repair via microhomology-mediated end joining An instance of double-strand break repair via nonhomologous end joining that is independent of factors important for V(D)J recombination (as opposed to classical nonhomologous end joining). It often results in a deletion with microhomology (i.e. 5-25bp homology) at the repair junction. Among different subclasses of nonhomologous end joining (NHEJ), alternative NHEJ appears to play a significant role in the etiology of mutations that arise during cancer development and treatment. GO:0009069 serine family amino acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009069 serine family amino acid metabolism The chemical reactions and pathways involving amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine. GO:0009068 aspartate family amino acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009068 aspartate family amino acid degradation|aspartate family amino acid breakdown|aspartate family amino acid catabolism The chemical reactions and pathways resulting in the breakdown of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine. GO:0009067 aspartate family amino acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009067 aspartate family amino acid biosynthesis|aspartate family amino acid anabolism|aspartate family amino acid synthesis|aspartate family amino acid formation The chemical reactions and pathways resulting in the formation of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine. GO:0009066 aspartate family amino acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009066 aspartate family amino acid metabolism The chemical reactions and pathways involving amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine. GO:0009076 obsolete histidine family amino acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009076 histidine family amino acid anabolism|histidine family amino acid synthesis|histidine family amino acid formation|histidine family amino acid biosynthetic process|histidine family amino acid biosynthesis OBSOLETE. The chemical reactions and pathways resulting in the formation of amino acids of the histidine family. GO:0010054 trichoblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010054 trichoblast cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a trichoblast, a root epidermal cell that will give rise to a root hair. GO:0009075 obsolete histidine family amino acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009075 histidine family amino acid metabolic process|histidine family amino acid metabolism OBSOLETE. The chemical reactions and pathways involving amino acids of the histidine family. GO:0010053 root epidermal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010053 The process in which a relatively unspecialized cell in the root epidermis acquires the specialized features of a trichoblast or atrichoblast. GO:0009074 aromatic amino acid family catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009074 aromatic amino acid family breakdown|aromatic amino acid family catabolism|aromatic amino acid family degradation The chemical reactions and pathways resulting in the breakdown of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan). GO:0010056 atrichoblast fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010056 The process involved in the specification of an atrichoblast. GO:0010055 atrichoblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010055 The process in which a relatively unspecialized cell acquires the specialized features of an atrichoblast, a root epidermal cell that will not give rise to a root hair. GO:0009073 aromatic amino acid family biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009073 MetaCyc:COMPLETE-ARO-PWY aromatic amino acid family biosynthetic process, shikimate pathway|aromatic amino acid family anabolism|aromatic amino acid family synthesis|aromatic amino acid family formation|aromatic amino acid family biosynthesis The chemical reactions and pathways resulting in the formation of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan). GO:0009072 aromatic amino acid family metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009072 aromatic amino acid family metabolism The chemical reactions and pathways involving aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan). GO:0010058 regulation of atrichoblast fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010058 Any process that modulates atrichoblast fate specification. SO:0000628 chromosomal_structural_element biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000628 chromosomal structural element Regions of the chromosome that are important for structural elements. GO:0009071 serine family amino acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009071 serine family amino acid degradation|serine family amino acid breakdown|serine family amino acid catabolism The chemical reactions and pathways resulting in the breakdown of amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine. GO:0010057 trichoblast fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010057 The process involved in the specification of a trichoblast. SO:0000627 insulator biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000627 http://en.wikipedia.org/wiki/Insulator_(genetics) INSDC_feature:regulatory|INSDC_qualifier:insulator|insulator element A regulatory region that 1) when located between a CRM and a gene's promoter prevents the CRM from modulating that genes expression and 2) acts as a chromatin boundary element or barrier that can block the encroachment of condensed chromatin from an adjacent region. GO:0009070 serine family amino acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009070 serine family amino acid anabolism|serine family amino acid biosynthesis|serine family amino acid synthesis|serine family amino acid formation The chemical reactions and pathways resulting in the formation of amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine. GO:0010059 positive regulation of atrichoblast fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010059 up-regulation of atrichoblast fate|upregulation of atrichoblast fate|up regulation of atrichoblast fate|activation of atrichoblast fate|stimulation of atrichoblast fate Any process that induces or promotes atrichoblast fate specification. GO:0034007 S-linalool synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034007 MetaCyc:4.2.3.25-RXN|EC:4.2.3.25|RHEA:24116|KEGG_REACTION:R07631 LIS|3S-linalool synthase activity|geranyl-diphosphate diphosphate-lyase [(3S)-linalool-forming] activity Catalysis of the reaction: geranyl diphosphate + H(2)O = (S)-linalool + diphosphate. SO:0000624 telomere biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000624 http://en.wikipedia.org/wiki/Telomere telomeric sequence|telomeric DNA|INSDC_feature:telomere A specific structure at the end of a linear chromosome, required for the integrity and maintenance of the end. GO:0034006 amorpha-4,11-diene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034006 MetaCyc:4.2.3.24-RXN|MetaCyc:RXN-8046|EC:4.2.3.24|RHEA:18325|KEGG_REACTION:R07630 2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (amorpha-4,11-diene-forming) activity|amorphadiene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = amorpha-4,11-diene + diphosphate. GO:0034005 germacrene-A synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034005 MetaCyc:4.2.3.23-RXN|RHEA:12516|KEGG_REACTION:R07649|EC:4.2.3.23 (+)-germacrene A synthase activity|germacrene A synthase activity|GAS|(+)-(10R)-germacrene A synthase activity|2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase [(+)-germacrene-A-forming] activity|2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (germacrene-A-forming) activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (+)-(R)-germacrene A + diphosphate. SO:0000625 silencer biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000625 http://en.wikipedia.org/wiki/Silencer_(DNA) INSDC_feature:regulatory|INSDC_qualifier:silencer A regulatory region which upon binding of transcription factors, suppress the transcription of the gene or genes they control. GO:0034004 germacradienol synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034004 MetaCyc:RXN-8648|RHEA:22436|EC:4.2.3.22|KEGG_REACTION:R07647 2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase [(1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol-forming] activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + H2O = (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + diphosphate. GO:0097688 glutamate receptor clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097688 glutamatergic receptor clustering The neurotransmitter-gated ion channel clustering process in which glutamate receptors are localized to distinct domains in the cell membrane. GO:0034003 vetispiradiene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034003 MetaCyc:RXN-4823|EC:4.2.3.21|KEGG_REACTION:R06523|RHEA:10340 vetispiradiene-forming farnesyl pyrophosphate cyclase activity|vetispiradiene cyclase activity|trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, vetispiradiene-forming) activity|pemnaspirodiene synthase activity|HVS Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + vetispiradiene. GO:0010050 vegetative phase change biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010050 Any process involved in the transition of a plant from a juvenile phase of vegetative development to an adult phase of vegetative development. GO:0097687 dinoflagellate antapical horn biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097687 A horn-shaped dinoflagellate antapex found in thecate species. GO:0034002 (R)-limonene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034002 MetaCyc:4.2.3.20-RXN|RHEA:10940|EC:4.2.3.20|KEGG_REACTION:R06120 geranyl-diphosphate diphosphate-lyase [cyclizing, (+)-(4R)-limonene-forming] activity|(+)-limonene synthase activity|geranyldiphosphate diphosphate lyase [(+)-(R)-limonene-forming] activity Catalysis of the reaction: geranyl diphosphate = (4R)-limonene + diphosphate. GO:0034001 chondroitin-sulfate-ABC exolyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034001 MetaCyc:4.2.2.21-RXN|EC:4.2.2.21 chondroitinase activity|chondroitinase ABC activity|chondroitin sulfate ABC lyase activity|chondroitin ABC eliminase activity|ChS ABC lyase activity|chondroitin sulfate ABC exoeliminase activity|chondroitin sulfate ABC exolyase activity|ChS ABC lyase II activity Catalysis of the exolytic cleavage of disaccharide residues from the non-reducing ends of both polymeric chondroitin sulfates and their oligosaccharide fragments. GO:0010052 guard cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010052 stomatal cell differentiation The process in which a guard mother cell acquires the specialized features of a guard cell. GO:0034000 chondroitin-sulfate-ABC endolyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034000 MetaCyc:4.2.2.20-RXN|EC:4.2.2.20 chondroitinase ABC activity|chondroitin sulfate ABC lyase activity|chondroitin sulfate ABC endoeliminase activity|chondroitin sulfate ABC endolyase activity|chondroitin ABC eliminase activity|ChS ABC lyase activity|ChS ABC lyase I activity|chondroitinase activity Catalysis of the endolytic cleavage of beta-1,4-galactosaminic bonds between N-acetylgalactosamine and either D-glucuronic acid or L-iduronic acid to produce a mixture of Delta4-unsaturated oligosaccharides of different sizes that are ultimately degraded to Delta4-unsaturated tetra- and disaccharides. GO:0097689 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0097689 GO:0010051 xylem and phloem pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010051 vascular tissue pattern formation The regionalization process that gives rise to the patterning of the conducting tissues. An example of this process is found in Arabidopsis thaliana. GO:0097651 phosphatidylinositol 3-kinase complex, class I biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097651 class I PI3K complex|class I phosphatidylinositol 3-kinase complex A phosphatidylinositol 3-kinase complex that contains a catalytic and a regulatory subunit of a phosphatidylinositol 3-kinase (PI3K) enzyme, plus one or more adaptor proteins. Class I PI3Ks phosphorylate phosphatidylinositol [PI], phosphatidylinositol-4-phosphate [PI(4)P] and phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2], and are divided into subclasses A and B according to the type of adaptor subunit with which they associate. The class I PI3K subfamily of genes comprises members in vertebrates, worm and fly, but none in yeast. GO:0097650 B axonemal microtubule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097650 B tubule An incomplete microtubule containing 10 protofilaments that fuses with a complete microtubule called A tubule (containing 13 protofilaments) to form an axonemal outer doublet. GO:0097653 unencapsulated part of cell biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097653 non-encapsulated part of cell The part of a cell encompassing the intracellular environment and the plasma membrane; it excludes any external encapsulating structures. GO:0097652 phosphatidylinositol 3-kinase complex, class II biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097652 class II PI3K complex|class II phosphatidylinositol 3-kinase complex A phosphatidylinositol 3-kinase complex that contains a catalytic subunit of a phosphatidylinositol 3-kinase (PI3K) enzyme and one or more adaptor proteins. There is no known obligatory regulatory subunit. The class II PI3K (PI3KC2) subfamily of genes has members in vertebrates, worm and fly, but none in yeast. GO:0010029 regulation of seed germination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010029 Any process that modulates the frequency, rate or extent of seed germination. GO:0009039 urease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009039 UM-BBD_reactionID:r0120|EC:3.5.1.5|MetaCyc:UREASE-RXN|RHEA:20557 urea amidohydrolase activity Catalysis of the reaction: urea + H2O = CO2 + 2 NH3. GO:0010028 xanthophyll cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010028 Wikipedia:Xanthophyll#Xanthophyll_cycle|MetaCyc:PWY-1141 A cyclic series of interconversions involving three xanthophylls, violoxanthin, antheraxanthin, and zeaxanthin. The xanthophyll cycle is involved in regulating energy dissipation in light harvesting complex II. CHEBI:133999 alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133999 GO:0009038 undecaprenol kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009038 EC:2.7.1.66 C55-isoprenyl alcohol phosphokinase activity|polyisoprenol kinase activity|isoprenoid alcohol phosphokinase activity|isoprenoid alcohol kinase (phosphorylating)|isoprenoid-alcohol kinase activity|ATP:undecaprenol phosphotransferase activity|C55-isoprenoid alcohol phosphokinase activity|C55-isoprenoid alcohol kinase activity|isoprenoid alcohol kinase activity Catalysis of the reaction: ATP + undecaprenol = ADP + undecaprenyl phosphate. GO:0009037 tyrosine-based site-specific recombinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009037 site-specific tyrosine recombinase activity|tyrosine recombinase Catalysis of the formation of new phosphodiester bonds between a pair of short, unique DNA target sequences; occurs through a phosphotyrosyl intermediate in which the target sequence is first cleaved by the nucleophilic attack by a tyrosine in the active site. GO:0009036 type II site-specific deoxyribonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009036 EC:3.1.21.4|MetaCyc:3.1.21.4-RXN type II restriction enzyme activity Catalysis of the endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates and 3' hydroxyls. Cleavage is dependent on the presence in the DNA of a specific recognition site; cleavage occurs at or very near this recognition site. GO:0009035 type I site-specific deoxyribonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009035 MetaCyc:3.1.21.3-RXN|EC:3.1.21.3 deoxyribonuclease (adenosine triphosphate-hydrolyzing)|type I restriction enzyme activity|adenosine triphosphate-dependent deoxyribonuclease activity|type I site-specific deoxyribonuclease activity|deoxyribonuclease (ATP- and S-adenosyl-L-methionine-dependent)|ATP-dependent DNase activity Catalysis of the endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5' or 3' protrusions; ATP is simultaneously hydrolyzed. Cleavage is dependent on the presence in the DNA of a specific recognition site. Cleavage may occur hundreds or thousands of base pairs away from the recognition site due to translocation of DNA. GO:0009034 tryptophanase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009034 MetaCyc:TRYPDEG-PWY|RHEA:19553|MetaCyc:TRYPTOPHAN-RXN|EC:4.1.99.1|UniPathway:UPA00332|KEGG_REACTION:R00673 L-tryptophanase activity|L-tryptophan indole-lyase (deaminating) activity|L-tryptophan indole-lyase activity|tryptophan catabolic process, using tryptophanase|L-tryptophan indole-lyase (deaminating; pyruvate forming) activity|TNase activity|tryptophan catabolism, using tryptophanase Catalysis of the reaction: L-tryptophan + H(2)O = indole + NH(4)(+) + pyruvate. GO:0009033 trimethylamine-N-oxide reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009033 RHEA:22024|MetaCyc:TMAOREDUCT-RXN trimethylamine oxide reductase|trimethylamine oxidase activity|NADH:trimethylamine-N-oxide oxidoreductase|trimethylamine N-oxide reductase Catalysis of the reaction: NADH + H+ + trimethylamine-N-oxide = NAD+ + trimethylamine + H2O. GO:0009043 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009043 CHEBI:133992 N-oleoylglycinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133992 GO:0010021 amylopectin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010021 amylopectin anabolism|amylopectin biosynthesis|amylopectin synthesis|amylopectin formation The chemical reactions and pathways resulting in the formation of amylopectin, the (1->4) linked alpha glucose units with alpha-(1->6) linkages. GO:0009042 valine-pyruvate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009042 RHEA:22912|KEGG_REACTION:R01215|EC:2.6.1.66|MetaCyc:VALINE-PYRUVATE-AMINOTRANSFER-RXN alanine-oxoisovalerate aminotransferase activity|valine--pyruvate aminotransferase activity|L-valine:pyruvate aminotransferase activity|transaminase C activity|alanine--valine transaminase activity|valine-pyruvate aminotransferase activity Catalysis of the reaction: L-valine + pyruvate = 3-methyl-2-oxobutanoate + L-alanine. CHEBI:133991 (9S,10E,12Z,14E,16S)-9,16-bis(hydroperoxy)octadecatrienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133991 GO:0010020 chloroplast fission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010020 chloroplast division The division of a chloroplast within a cell to form two or more separate chloroplast compartments. This division occurs independently of mitosis. GO:0010023 proanthocyanidin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010023 MetaCyc:PWY-641 proanthocyanidin anabolism|proanthocyanidin synthesis|proanthocyanidin formation|proanthocyanidin biosynthesis The chemical reactions and pathways resulting in the formation of proanthocyanidin. GO:0009041 uridylate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009041 EC:2.7.4.22 Catalysis of the reaction: ATP + (d)UMP = ADP + (d)UDP. CHEBI:133994 alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133994 GO:0010022 meristem determinacy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010022 The process in which a meristem becomes determinate (i.e. ceases to produce lateral organs and may or may not terminally differentiate). GO:0009040 ureidoglycolate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009040 MetaCyc:R165-RXN|EC:1.1.1.154 (S)-ureidoglycolate:NAD(P)+ oxidoreductase activity Catalysis of the reaction: (S)-ureidoglycolate + NAD(P)+ = oxalureate + NAD(P)H + H+. CHEBI:133993 4'-O-methylnorbelladine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133993 GO:0010025 wax biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010025 MetaCyc:PWY-282 wax synthesis|wax formation|wax biosynthesis|wax anabolism The chemical reactions and pathways resulting in the formation of wax, which includes C16 and C18 fatty acids. CHEBI:133996 (4aR,10bS)-noroxomaritidine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133996 GO:0010024 phytochromobilin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010024 phytochromobilin biosynthesis|phytochromobilin anabolism|phytochromobilin synthesis|phytochromobilin formation The chemical reactions and pathways resulting in the formation of phytochromobilin, which involves the oxidative cleavage of heme by a heme oxygenase(HO) to form biliverdin IX alpha. CHEBI:133995 (4aS,10bR)-noroxomaritidine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133995 GO:0010027 thylakoid membrane organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010027 thylakoid membrane organisation|thylakoid membrane organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the thylakoid membrane. CHEBI:133998 alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133998 GO:0010026 trichome differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010026 trichome cell differentiation The process in which a relatively unspecialized epidermal cell acquires the specialized features of a trichome cell. An example of this process is found in Arabidopsis thaliana. GO:0097659 nucleic acid-templated transcription biolink:BiologicalProcess go-plus goslim_mouse|gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0097659 The cellular synthesis of RNA on a template of nucleic acid (DNA or RNA). SO:0000657 repeat_region biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000657 INSDC_qualifier:other|repeat region|INSDC_feature:repeat_region A region of sequence containing one or more repeat units. GO:0097658 Asi complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097658 A nuclear ubiquitin ligase multiprotein complex located in the inner nuclear membrane (INM) that recognizes and ubiquitinates misfolded INM proteins and also some proteins involved in sterol biosynthesis, during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligases Asi1p and Asi3p. CHEBI:456215 adenosine 5'-monophosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_456215 GO:0097655 serpin family protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097655 SERPIN family protein binding Interacting selectively and non-covalently with any member of the serpin protein family (serine protease inhibitors or classified inhibitor family I4). Serpins are a broadly distributed family of protease inhibitors that use a conformational change to inhibit target enzymes. They are central in controlling many important proteolytic cascades. The majority of serpins inhibit serine proteases, but serpins that inhibit caspases and papain-like cysteine proteases have also been identified. Rarely, serpins perform a non-inhibitory function; for example, several human serpins function as hormone transporters and certain serpins function as molecular chaperones or tumor suppressors. GO:0097654 platelet SNARE complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097654 A SNARE complex that is capable of fusing intracellular vesicles to the plasma membrane of platelets for exocytosis of alpha-granules or dense granules. Contains isoforms of VAMP, SNAP and syntaxin proteins. Ternary SNARE complexes interact in a circular array to form ring complexes or channels around the membrane fusion. A common composition in human is VAMP-8, SNAP-23 and syntaxin-2 or -4. GO:0097657 3',5'-nucleotide bisphosphate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097657 RHEA:43532 Catalysis of the reaction: 3',5'-nucleotide bisphosphate + H20 = 5'-nucleotide monophosphate + phosphate. SO:0000655 ncRNA biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000655 http://www.gencodegenes.org/gencode_biotypes.html|http://en.wikipedia.org/wiki/NcRNA INSDC_qualifier:other|noncoding RNA|known_ncrna An RNA transcript that does not encode for a protein rather the RNA molecule is the gene product. CHEBI:133990 (9S,10E,12Z,14E,16S)-9,16-bis(hydroperoxy)octadecatrienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133990 CHEBI:456216 ADP(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_456216 GO:0097656 cell-cell self recognition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097656 kin recognition|kin discrimination|self recognition A cell-cell recognition process by which a cell distinguishes between self and non self during cooperative behavior, such as early development. GO:0097662 SCF-Das1 ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097662 An SCF ubiquitin ligase complex in which the F-box protein is Das1 in S. cerevisiae. GO:0097661 SCF-Ctf13 ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097661 An SCF ubiquitin ligase complex in which the F-box protein is Ctf13 in S. cerevisiae. SO:0000651 large_subunit_rRNA biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000651 LSU RNA|LSU rRNA|large subunit rRNA Ribosomal RNA transcript that structures the large subunit of the ribosome. GO:0097664 SCF-Grr1/Pof2 ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097664 An SCF ubiquitin ligase complex in which the F-box protein is Grr1 in S. cerevisiae (Pof2 in S. pombe). GO:0097663 SCF-Dia2/Pof3 ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097663 An SCF ubiquitin ligase complex in which the F-box protein is Dia2 in S. cerevisiae (Pof3 in S. pombe). GO:0097660 SCF-Cdc4 ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097660 An SCF ubiquitin ligase complex in which the F-box protein is Cdc4 in S. cerevisiae. GO:0010039 response to iron ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010039 response to iron Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus. GO:0009049 obsolete aspartic-type signal peptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009049 aspartic-type signal peptidase activity OBSOLETE. Catalysis of the cleavage of a signal peptide from a protein precursor by an aspartic endopeptidase mechanism. GO:0009048 dosage compensation by inactivation of X chromosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009048 Wikipedia:X-inactivation chromosome inactivation|Barr body formation|X chromosome inactivation Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex. GO:0009047 dosage compensation by hyperactivation of X chromosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009047 Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global hyperactivation of all, or most of, the genes on the X-chromosome in the heterogametic sex, leading to a two-fold increase in gene expression from this chromosome. An example of this is found in Drosophila melanogaster. GO:0009046 zinc D-Ala-D-Ala carboxypeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009046 MetaCyc:3.4.17.14-RXN|EC:3.4.17.14 DD-carboxypeptidase|Zn2+ G peptidase activity|G enzyme|DD-carboxypeptidase-transpeptidase activity|D-alanyl-D-alanine hydrolase activity|Zn(2+) G peptidase activity|D-alanyl-D-alanine-cleaving carboxypeptidase activity Catalysis of the cleavage of the D-alanyl-D-alanine bond in (Ac)2-L-lysyl-D-alanyl-D-alanine. GO:0009045 xylose isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009045 RHEA:22816|EC:5.3.1.5|MetaCyc:XYLISOM-RXN D-xylose aldose-ketose-isomerase activity|D-xylose isomerase activity|D-xylose ketol-isomerase activity|D-xylose ketoisomerase activity Catalysis of the reaction: D-xylose = D-xylulose. GO:0009044 xylan 1,4-beta-xylosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0009044 EC:3.2.1.37|MetaCyc:3.2.1.37-RXN 1,4-beta-D-xylan xylohydrolase activity|exo-1,4-beta-xylosidase activity|beta-xylosidase activity|beta-D-xylopyranosidase activity|xylobiase activity|exo-1,4-beta-D-xylosidase activity|exo-1,4-xylosidase activity Catalysis of the hydrolysis of (1->4)-beta-D-xylans so as to remove successive D-xylose residues from the non-reducing termini. GO:0009054 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009054 GO:0010032 meiotic chromosome condensation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010032 chromosome condensation involved in meiotic cell cycle Compaction of chromatin structure prior to meiosis in eukaryotic cells. GO:0009053 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0009053 GO:0010031 circumnutation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010031 The organismal movement by which the tip of a plant organ follows a spiral pattern as a consequence of growth. GO:0009052 pentose-phosphate shunt, non-oxidative branch biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009052 MetaCyc:P21-PWY|MetaCyc:NONOXIPENT-PWY pentose phosphate pathway, non-oxidative branch|pentose phosphate shunt, non-oxidative branch|pentose-phosphate pathway, non-oxidative branch The branch of the pentose-phosphate shunt which does not involve oxidation reactions. It comprises a series of sugar phosphate interconversions, starting with ribulose 5-P and producing fructose 6-P and glyceraldehyde 3-P. GO:0010034 response to acetate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010034 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus. GO:0010033 response to organic substance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010033 process resulting in tolerance to organic substance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus. GO:0009051 pentose-phosphate shunt, oxidative branch biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009051 MetaCyc:OXIDATIVEPENT-PWY pentose phosphate pathway, oxidative branch|pentose phosphate shunt, oxidative branch|oxidative branch, pentose pathway|pentose-phosphate pathway, oxidative branch|oxidative pentose phosphate pathway The branch of the pentose-phosphate shunt which involves the oxidation of glucose 6-P and produces ribulose 5-P, reduced NADP+ and carbon dioxide (CO2). GO:0010036 response to boron-containing substance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010036 response to boron Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a boron-containing substance stimulus. GO:0009050 glycopeptide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0009050 glycopeptide catabolism|glycopeptide degradation|glycopeptide breakdown The chemical reactions and pathways resulting in the breakdown of glycopeptides, any compound in which carbohydrate is covalently attached to an oligopeptide composed of residues of L and/or D-amino acids. The term usually denotes a product of proteolytic degradation of a glycoprotein but includes glycated peptide. GO:0010035 response to inorganic substance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010035 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus. GO:0010038 response to metal ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010038 response to heavy metal|response to metal|heavy metal sensitivity/resistance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus. GO:0010037 response to carbon dioxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010037 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus. SO:0000646 siRNA biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000646 http://en.wikipedia.org/wiki/SiRNA small interfering RNA|INSDC_feature:ncRNA|INSDC_qualifier:siRNA A small RNA molecule that is the product of a longer exogenous or endogenous dsRNA, which is either a bimolecular duplex or very long hairpin, processed (via the Dicer pathway) such that numerous siRNAs accumulate from both strands of the dsRNA. SRNAs trigger the cleavage of their target molecules. GO:0097669 SCF-Skp2 ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097669 An SCF ubiquitin ligase complex in which the F-box protein is Skp2 in S. cerevisiae. GO:0097666 SCF-Met30/Pof1 ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097666 An SCF ubiquitin ligase complex in which the F-box protein is Met30 in S. cerevisiae (Pof1 in S pombe). GO:0097665 SCF-Mdm30 ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097665 An SCF ubiquitin ligase complex in which the F-box protein is Mdm30 in S. cerevisiae. SO:0000644 antisense_RNA biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000644 http://en.wikipedia.org/wiki/Antisense_RNA antisense RNA|INSDC_qualifier:antisense_RNA|INSDC_feature:ncRNA Antisense RNA is RNA that is transcribed from the coding, rather than the template, strand of DNA. It is therefore complementary to mRNA. GO:0010030 positive regulation of seed germination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0010030 stimulation of seed germination|up-regulation of seed germination|activation of seed germination|up regulation of seed germination|upregulation of seed germination Any process that activates or increase the rate of seed germination. GO:0097668 SCF-Saf1/Pof9 ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097668 An SCF ubiquitin ligase complex in which the F-box protein is Saf1 in S. cerevisiae (Pof9 in S. pombe). GO:0097667 SCF-Rcy1/Pof6 ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097667 An SCF ubiquitin ligase complex in which the F-box protein is Rcy1 in S. cerevisiae (Pof6 in S. pombe). PO:0025541 bundle sheath cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025541 celula de la vaina del haz vascular (Spanish, exact)|維管束鞘細胞 (Japanese, exact) A ground tissue cell (PO:0000076) that is part of a bundle sheath (PO:0006023). GO:0048626 myoblast fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048626 The process in which a cell becomes capable of differentiating autonomously into a myoblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. CHEBI:63571 trisaccharide derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63571 UBERON:0035044 olfactory cortex layer 3 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035044 Deepest layer of olfactory cortex GO:0048625 myoblast fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048625 The process in which the developmental fate of a cell becomes restricted such that it will develop into a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. GO:0048624 plantlet formation on parent plant biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048624 vegetative vivipary|vivipary The process in which a new plantlet develops from a meristem on the plant body. As part of this process, when the plantlet is large enough to live independently, the physical connection between the new plantlet and the main plant is severed. GO:0048623 seed germination on parent plant biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048623 non-vegetative vivipary|vivipary|pre-harvest sprouting The process in which a seed germinates before being shed from the parent plant. GO:0048622 obsolete reproductive sporulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048622 reproductive sporulation OBSOLETE. The formation of reproductive spores. CHEBI:63576 maltose 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63576 UBERON:0035049 excretory duct of salivary gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035049 Any of the interlobular excretory ducts of a salivary gland which are found in the connective tissue septa and formed by the union of several intralobular striated (secretory) ducts[MP,generalized]. GO:0048621 post-embryonic digestive tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048621 post-embryonic gut morphogenesis The process, occurring during the post-embryonic phase, by which the anatomical structures of the digestive tract are generated and organized. The digestive tract is the anatomical structure through which food passes and is processed. GO:0048620 post-embryonic hindgut morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048620 The process in which the anatomical structures of the hindgut are generated and organized, during the post-embryonic phase. CHEBI:63573 guanyl deoxyribonucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63573 CHEBI:63579 18-HETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63579 GO:0048629 trichome patterning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048629 trichome spacing|trichome pattern formation|trichome pattern specification|trichome pattern biosynthesis|trichome distribution The regionalization process of establishing the non-random spatial arrangement of trichomes on the surface and margin of a leaf. Process involves signaling between adjacent epidermal cells that results in differentiation of some epidermal cells into trichomes. GO:0048628 myoblast maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048628 A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast to attain its fully functional state. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. GO:0048627 myoblast development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048627 The process whose specific outcome is the progression of the myoblast over time, from its formation to the mature structure. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. PO:0025530 reproductive shoot system development stage biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025530 A shoot system development stage (PO:0025527) that has as primary participant a reproductive shoot system (PO:0025082). SO:0000673 transcript biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000673 http://en.wikipedia.org/wiki/RNA INSDC_feature:misc_RNA An RNA synthesized on a DNA or RNA template by an RNA polymerase. UBERON:0035050 excretory duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035050 UBERON:0035053 interlobular duct of salivary gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035053 GO:0048637 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048637 CHEBI:63582 1-palmitoylglycerol 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63582 GO:0048636 positive regulation of muscle organ development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048636 up regulation of muscle development|upregulation of muscle development|stimulation of muscle development|up-regulation of muscle development|activation of muscle development Any process that activates, maintains or increases the rate of muscle development. GO:0048635 negative regulation of muscle organ development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048635 downregulation of muscle development|down regulation of muscle development|inhibition of muscle development|down-regulation of muscle development Any process that stops, prevents, or reduces the frequency, rate or extent of muscle development. CHEBI:63580 ribavirin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63580 GO:0048634 regulation of muscle organ development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048634 Any process that modulates the frequency, rate or extent of muscle development. GO:0048633 positive regulation of skeletal muscle tissue growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048633 upregulation of skeletal muscle growth|stimulation of skeletal muscle growth|up-regulation of skeletal muscle growth|activation of skeletal muscle growth|up regulation of skeletal muscle growth Any process that activates, maintains or increases the rate of skeletal muscle growth. GO:0048632 negative regulation of skeletal muscle tissue growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048632 downregulation of skeletal muscle growth|down regulation of skeletal muscle growth|inhibition of skeletal muscle growth|down-regulation of skeletal muscle growth Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle growth. CHEBI:87531 prenyl-FMNH2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87531 GO:0048631 regulation of skeletal muscle tissue growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048631 Any process that modulates the frequency, rate or extent of skeletal muscle growth. GO:0048630 skeletal muscle tissue growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048630 The increase in size or mass of a skeletal muscle. This may be due to a change in the fiber number or size. CHEBI:87538 16alpha-hydroxydehydroepiandrosterone 3-sulfate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87538 GO:0048639 positive regulation of developmental growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048639 up-regulation of developmental growth|activation of developmental growth|up regulation of developmental growth|upregulation of developmental growth|stimulation of developmental growth Any process that activates, maintains or increases the rate of developmental growth. PO:0025528 bud development stage biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025528 A shoot system development stage (PO:0025527) that has as primary participant a bud (PO:0009006). GO:0048638 regulation of developmental growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048638 Any process that modulates the frequency, rate or extent of developmental growth. PO:0025527 shoot system development stage biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025527 A collective plant organ structure development stage (PO:0025338) that begins with the onset of the plant organ development stage (PO:0025339) and ends with either gametophyte senescent stage (PO:0025343) or sporophyte senescent stage (PO:0007017) or death. PO:0025526 body cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025526 gymnosperm generative cell (exact) A spermatogenous cell (PO:0025525) of the microgametophyte (PO:0025280) that divides to produce a vegetative cell (PO:0020099) and the pollen sperm cell (PO:0025121). PO:0025525 spermatogenous cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025525 A native plant cell (PO:0025606) that gives rise to one or more plant sperm cells (PO:0000084). GO:0048640 negative regulation of developmental growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048640 down regulation of developmental growth|inhibition of developmental growth|down-regulation of developmental growth|downregulation of developmental growth Any process that stops, prevents, or reduces the frequency, rate or extent of developmental growth. GO:1903809 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1903809 GO:1903808 L-tyrosine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903808 L-tyrosine import|L-tyrosine uptake|L-tyrosine import into cell The directed movement of L-tyrosine from outside of a cell, across the plasma membrane and into the cytosol. GO:1903807 L-threonine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903807 L-threonine import into cell|L-threonine import|L-threonine uptake The directed movement of L-threonine from outside of a cell, across the plasma membrane and into the cytosol. GO:1903806 L-isoleucine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903806 L-isoleucine import into cell|isoleucine import|L-isoleucine import The directed movement of L-isoleucine from outside of a cell, across the plasma membrane and into the cytosol. GO:1903805 L-valine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903805 valine import|L-valine import into cell The directed movement of L-valine from outside of a cell, across the plasma membrane and into the cytosol. CHEBI:63590 18-HETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63590 GO:1903804 glycine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903804 glycine import|glycine import into cell The directed movement of glycine from outside of a cell, across the plasma membrane and into the cytosol. PR:000049989 glucagon-like receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000049989 glucagon receptor A secretin-like G-protein coupled receptor that is a translation product of the human GHRHR, GIPR, GLP1R, GLP2R, GCGR, or SCTR genes, 1:1 orthologs thereof, or a semi-ortholog thereof. GO:1903803 L-glutamine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903803 L-glutamine import|L-glutamine uptake|L-glutamine import into cell The directed movement of L-glutamine from outside of a cell, across the plasma membrane and into the cytosol. GO:1903802 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1903802 GO:1903801 L-leucine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903801 L-leucine uptake|L-leucine import into cell|leucine uptake|L-leucine import|leucine import The directed movement of L-leucine from outside of a cell, across the plasma membrane and into the cytosol. GO:0048648 caste determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048648 The process in which individuals, having the potential to develop any of several distinct developmental paths, have their individual developmental fate determined in response to environmental and/or genetic cues. Individuals with distinct developmental fates perform different functions in a colony of social insects. CHEBI:63594 1-ribosyltriazole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63594 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903800 positive regulation of microRNA biogenesis|upregulation of miRNA biogenesis|upregulation of gene silencing by miRNA, production of miRNAs|up-regulation of microRNA-mediated gene silencing, production of microRNAs|up-regulation of microRNA metabolism|activation of microRNA metabolic process|upregulation of production of microRNAs involved in gene silencing by microRNA|up-regulation of production of miRNAs involved in gene silencing by miRNA|activation of production of miRNAs involved in gene silencing by miRNA|activation of microRNA biogenesis|up-regulation of miRNA-mediated gene silencing, production of miRNAs|positive regulation of microRNA metabolic process|upregulation of microRNA biosynthesis|upregulation of miRNA processing|upregulation of microRNA biosynthetic process|up regulation of microRNA metabolic process|up-regulation of miRNA biogenesis|upregulation of microRNA-mediated gene silencing, production of microRNAs|up regulation of gene silencing by miRNA, production of miRNAs|upregulation of microRNA metabolism|up-regulation of microRNA biogenesis|activation of production of microRNAs involved in gene silencing by microRNA|activation of gene silencing by miRNA, production of miRNAs|up-regulation of production of microRNAs involved in gene silencing by microRNA|positive regulation of gene silencing by miRNA, production of miRNAs|upregulation of miRNA-mediated gene silencing, production of miRNAs|activation of miRNA biogenesis|up regulation of production of miRNAs involved in gene silencing by miRNA|up-regulation of miRNA processing|activation of miRNA processing|up regulation of microRNA biosynthetic process|up regulation of microRNA biosynthesis|upregulation of microRNA metabolic process|upregulation of microRNA biogenesis|positive regulation of microRNA biosynthesis|up regulation of microRNA-mediated gene silencing, production of microRNAs|positive regulation of microRNA biosynthetic process|positive regulation of miRNA biogenesis|activation of microRNA-mediated gene silencing, production of microRNAs|up regulation of microRNA metabolism|up regulation of miRNA biogenesis|positive regulation of microRNA-mediated gene silencing, production of microRNAs|positive regulation of production of microRNAs involved in gene silencing by microRNA|positive regulation of microRNA metabolism|up-regulation of gene silencing by miRNA, production of miRNAs|up regulation of miRNA-mediated gene silencing, production of miRNAs|activation of microRNA biosynthetic process|activation of microRNA biosynthesis|activation of miRNA-mediated gene silencing, production of miRNAs|up regulation of production of microRNAs involved in gene silencing by microRNA|positive regulation of miRNA-mediated gene silencing, production of miRNAs|upregulation of production of miRNAs involved in gene silencing by miRNA|activation of microRNA metabolism|positive regulation of miRNA processing|up-regulation of microRNA metabolic process|up regulation of miRNA processing|up regulation of microRNA biogenesis|up-regulation of microRNA biosynthetic process|up-regulation of microRNA biosynthesis Any process that activates or increases the frequency, rate or extent of production of miRNAs involved in gene silencing by miRNA. GO:0048647 polyphenic determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048647 The process in which individuals that have the potential to develop any of several possible distinct developmental paths have their individual developmental fates determined in response to environmental and/or genetic cues. CHEBI:63593 1-glycosyltriazole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63593 GO:0048646 anatomical structure formation involved in morphogenesis biolink:BiologicalProcess go-plus goslim_chembl|goslim_generic http://purl.obolibrary.org/obo/GO_0048646 formation of an anatomical structure involved in morphogenesis The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. CHEBI:63592 maltose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63592 GO:0048645 animal organ formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048645 initiation of an animal organ primordium|animal organ primordium initiation The process pertaining to the initial formation of an animal organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. Organs are a natural part or structure in an animal or a plant, capable of performing some special action (termed its function), which is essential to the life or well-being of the whole. The heart and lungs are organs of animals, and the petal and leaf are organs of plants. In animals the organs are generally made up of several tissues, one of which usually predominates, and determines the principal function of the organ. GO:0048644 muscle organ morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048644 The process in which the anatomical structures of muscle are generated and organized. GO:0048643 positive regulation of skeletal muscle tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048643 up-regulation of skeletal muscle development|upregulation of skeletal muscle development|up regulation of skeletal muscle development|activation of skeletal muscle development|stimulation of skeletal muscle development Any process that activates, maintains or increases the rate of skeletal muscle tissue development. GO:0048642 negative regulation of skeletal muscle tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048642 inhibition of skeletal muscle development|down regulation of skeletal muscle development|downregulation of skeletal muscle development|down-regulation of skeletal muscle development Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle tissue development. GO:0048641 regulation of skeletal muscle tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048641 Any process that modulates the frequency, rate or extent of skeletal muscle tissue development. GO:0048649 caste determination, influence by genetic factors biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048649 The process in which individuals, having the potential to develop any of several distinct developmental paths, have their individual developmental fate determined in response to genetic cues. Individuals with distinct developmental fates perform different functions in a colony of social insects. SO:0000699 junction biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000699 boundary|breakpoint A sequence_feature with an extent of zero. GO:0048651 polyphenic determination, influence by environmental factors biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048651 The process in which individuals that have the potential to develop any of several possible distinct developmental paths have their individual developmental fates determined in response to environmental cues. GO:1903819 detection of stimulus involved in mitotic cytokinesis checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903819 stimulus sensing involved in mitotic cytokinesis checkpoint|perception of stimulus involved in mitotic cytokinesis checkpoint|stimulus detection involved in mitotic cytokinesis checkpoint Any detection of stimulus that is involved in a mitotic cytokinesis checkpoint. GO:0048650 caste determination, influence by environmental factors biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048650 The process in which individuals, having the potential to develop any of several distinct developmental paths, have their individual developmental fate determined in response to environmental cues. Individuals with distinct developmental fates perform different functions in a colony of social insects. GO:1903818 positive regulation of voltage-gated potassium channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903818 upregulation of voltage-sensitive potassium channel|activation of voltage-gated potassium channel activity|upregulation of voltage gated potassium channel activity|up-regulation of voltage-dependent potassium channel activity|activation of voltage-dependent potassium channel activity|up-regulation of voltage-gated potassium ion channel activity|activation of voltage-gated potassium ion channel activity|up regulation of voltage-sensitive potassium channel|positive regulation of voltage-sensitive potassium channel|up-regulation of voltage gated potassium channel activity|activation of voltage-sensitive potassium channel|up regulation of voltage-gated potassium channel activity|activation of voltage gated potassium channel activity|positive regulation of voltage-dependent potassium channel activity|positive regulation of voltage-gated potassium ion channel activity|up regulation of voltage-dependent potassium channel activity|up regulation of voltage-gated potassium ion channel activity|upregulation of voltage-gated potassium channel activity|up-regulation of voltage-sensitive potassium channel|positive regulation of voltage gated potassium channel activity|up regulation of voltage gated potassium channel activity|upregulation of voltage-dependent potassium channel activity|upregulation of voltage-gated potassium ion channel activity|up-regulation of voltage-gated potassium channel activity Any process that activates or increases the frequency, rate or extent of voltage-gated potassium channel activity. GO:1903817 negative regulation of voltage-gated potassium channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903817 down regulation of voltage gated potassium channel activity|inhibition of voltage gated potassium channel activity|down regulation of voltage-sensitive potassium channel|down-regulation of voltage-gated potassium channel activity|downregulation of voltage-sensitive potassium channel|negative regulation of voltage-dependent potassium channel activity|down-regulation of voltage-dependent potassium channel activity|negative regulation of voltage-gated potassium ion channel activity|down-regulation of voltage-gated potassium ion channel activity|downregulation of voltage-gated potassium channel activity|negative regulation of voltage-sensitive potassium channel|down-regulation of voltage-sensitive potassium channel|down-regulation of voltage gated potassium channel activity|negative regulation of voltage gated potassium channel activity|down regulation of voltage-gated potassium channel activity|downregulation of voltage-dependent potassium channel activity|inhibition of voltage-gated potassium channel activity|downregulation of voltage-gated potassium ion channel activity|inhibition of voltage-sensitive potassium channel|down regulation of voltage-dependent potassium channel activity|down regulation of voltage-gated potassium ion channel activity|inhibition of voltage-dependent potassium channel activity|downregulation of voltage gated potassium channel activity|inhibition of voltage-gated potassium ion channel activity Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated potassium channel activity. GO:1903816 positive regulation of collecting lymphatic vessel constriction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903816 up-regulation of lymphatic vessel myogenic constriction|activation of lymphatic vessel myogenic constriction|up-regulation of collecting lymphatic vessel constriction|activation of collecting lymphatic vessel constriction|positive regulation of lymphatic vessel myogenic constriction|up regulation of lymphatic vessel myogenic constriction|up regulation of collecting lymphatic vessel constriction|upregulation of lymphatic vessel myogenic constriction|upregulation of collecting lymphatic vessel constriction Any process that activates or increases the frequency, rate or extent of collecting lymphatic vessel constriction. UBERON:0035074 duct of apocrine sweat gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035074 ductal part of apocrine sweat gland GO:1903815 negative regulation of collecting lymphatic vessel constriction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903815 down-regulation of lymphatic vessel myogenic constriction|negative regulation of lymphatic vessel myogenic constriction|down-regulation of collecting lymphatic vessel constriction|downregulation of lymphatic vessel myogenic constriction|downregulation of collecting lymphatic vessel constriction|down regulation of lymphatic vessel myogenic constriction|inhibition of lymphatic vessel myogenic constriction|down regulation of collecting lymphatic vessel constriction|inhibition of collecting lymphatic vessel constriction Any process that stops, prevents or reduces the frequency, rate or extent of collecting lymphatic vessel constriction. GO:1903814 regulation of collecting lymphatic vessel constriction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903814 regulation of lymphatic vessel myogenic constriction Any process that modulates the frequency, rate or extent of collecting lymphatic vessel constriction. UBERON:0035075 thymus subunit biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035075 lobe or lobule of thymus GO:1903813 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1903813 GO:1903812 L-serine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903812 L-serine import into cell The directed movement of L-serine into a cell. GO:0048659 smooth muscle cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048659 SMC proliferation The multiplication or reproduction of smooth muscle cells, resulting in the expansion of a cell population. PR:000049997 leukotriene receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000049997 A rhodopsin-like G-protein coupled receptor that is a translation product of the human LTB4R, LTB4R2, CYSLTR1, CYSLTR2, or OXER1 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. GO:1903811 L-asparagine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903811 L-asparagine import into cell|asparagine import The directed movement of L-asparagine from outside of a cell, across the plasma membrane and into the cytosol. GO:0048658 anther wall tapetum development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048658 tapetal layer development|tapetum development The process whose specific outcome is the progression of the anther wall tapetum over time, from its formation to the mature structure. GO:1903810 L-histidine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903810 L-histidine import|histidine import|L-histidine import into cell The directed movement of L-histidine from outside of a cell, across the plasma membrane and into the cytosol. GO:0048657 anther wall tapetum cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048657 tapetal cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an anther cell wall tapetum cell. The tapetum is a layer of cells that provides a source of nutrition for the pollen grains as they mature. GO:0048656 anther wall tapetum formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048656 tapetal layer formation|tapetum formation The process that gives rise to the anther wall tapetum. This process pertains to the initial formation of a structure from unspecified parts. The anther wall tapetum is a layer of cells that provides a source of nutrition for the pollen grains as they mature. GO:0048655 anther wall tapetum morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048655 tapetal layer morphogenesis|differentiation of tapetal layer|tapetum morphogenesis The process in which the anatomical structures of the anther wall tapetum are generated and organized. The anther wall tapetum is a layer of cells that provides a source of nutrition for the pollen grains as they mature. GO:0048654 anther morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048654 The process in which the anatomical structures of the anther are generated and organized. GO:0048653 anther development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048653 The process whose specific outcome is the progression of the anther over time, from its formation to the mature structure. PR:000049994 histamine receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000049994 A rhodopsin-like G-protein coupled receptor that is a translation product of the human HRH1 to HRH4 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. GO:0048652 polyphenic determination, influence by genetic factors biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048652 The process in which individuals that have the potential to develop any of several possible distinct developmental paths have their individual developmental fates determined in response to genetic cues. GO:0048662 negative regulation of smooth muscle cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048662 down-regulation of smooth muscle cell proliferation|downregulation of smooth muscle cell proliferation|down regulation of smooth muscle cell proliferation|inhibition of smooth muscle cell proliferation|negative regulation of SMC proliferation Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation. GO:0048661 positive regulation of smooth muscle cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048661 up regulation of smooth muscle cell proliferation|positive regulation of SMC proliferation|upregulation of smooth muscle cell proliferation|stimulation of smooth muscle cell proliferation|up-regulation of smooth muscle cell proliferation|activation of smooth muscle cell proliferation Any process that activates or increases the rate or extent of smooth muscle cell proliferation. GO:1903829 positive regulation of cellular protein localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903829 up regulation of channel localizer activity|upregulation of cellular protein localization|up regulation of cellular protein localisation|positive regulation of cellular protein localisation|activation of cellular protein localisation|upregulation of channel localizer activity|up regulation of cellular protein localization|activation of cellular protein localization|up-regulation of cellular protein localisation|up-regulation of channel localizer activity|activation of channel localizer activity|up-regulation of cellular protein localization|upregulation of cellular protein localisation|positive regulation of channel localizer activity Any process that activates or increases the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell. GO:0048660 regulation of smooth muscle cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048660 regulation of SMC proliferation Any process that modulates the frequency, rate or extent of smooth muscle cell proliferation. GO:1903828 negative regulation of cellular protein localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903828 downregulation of cellular protein localisation|downregulation of channel localizer activity|down regulation of cellular protein localization|down regulation of channel localizer activity|downregulation of cellular protein localization|negative regulation of cellular protein localisation|down-regulation of cellular protein localisation|inhibition of channel localizer activity|inhibition of cellular protein localisation|down-regulation of cellular protein localization|inhibition of cellular protein localization|down-regulation of channel localizer activity|negative regulation of channel localizer activity|down regulation of cellular protein localisation Any process that stops, prevents or reduces the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell. GO:1903827 regulation of cellular protein localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903827 regulation of channel localizer activity|regulation of cellular protein localisation Any process that modulates the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell. GO:1903826 arginine transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903826 The directed movement of arginine across a membrane. GO:1903825 organic acid transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903825 The process in which an organic acid is transported across a membrane. GO:1903824 negative regulation of telomere single strand break repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903824 downregulation of telomere single strand break repair|down regulation of single strand break repair in telomere|down regulation of telomere SSBR|inhibition of single strand break repair in telomere|downregulation of telomere SSBR|down-regulation of telomere single strand break repair|down regulation of telomere single-strand break repair|downregulation of telomere single-strand break repair|down-regulation of telomere SSBR|down-regulation of telomeric single strand break repair|negative regulation of telomere SSBR|negative regulation of telomeric single strand break repair|inhibition of telomere single strand break repair|negative regulation of single strand break repair in telomere|down-regulation of single strand break repair in telomere|negative regulation of telomere single-strand break repair|down-regulation of telomere single-strand break repair|downregulation of telomeric single strand break repair|inhibition of telomere SSBR|down regulation of telomeric single strand break repair|inhibition of telomeric single strand break repair|down regulation of telomere single strand break repair|inhibition of telomere single-strand break repair|downregulation of single strand break repair in telomere Any process that stops, prevents or reduces the frequency, rate or extent of telomere single strand break repair. GO:1903823 telomere single strand break repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903823 telomere SSBR|telomere single-strand break repair|single strand break repair in telomere|telomeric single strand break repair Single strand break repair that takes place in a telomere. GO:1903822 signal transduction involved in morphogenesis checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903822 signalling cascade involved in septin checkpoint|signaling cascade involved in morphogenesis checkpoint|signaling cascade involved in septin checkpoint|signalling cascade involved in morphogenesis checkpoint|signalling pathway involved in septin checkpoint|signaling pathway involved in septin checkpoint|signaling pathway involved in morphogenesis checkpoint|signalling pathway involved in morphogenesis checkpoint|signal transduction involved in septin checkpoint Any signal transduction that is involved in morphogenesis checkpoint. GO:0048669 collateral sprouting in absence of injury biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048669 The process in which outgrowths develop from the axons of intact undamaged neurons. GO:0048668 collateral sprouting biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048668 axon branching The process in which outgrowths develop from the shafts of existing axons. GO:1903821 detection of stimulus involved in morphogenesis checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903821 perception of stimulus involved in septin checkpoint|detection of stimulus involved in septin checkpoint|stimulus sensing involved in septin checkpoint|stimulus detection involved in morphogenesis checkpoint|stimulus detection involved in septin checkpoint|stimulus sensing involved in morphogenesis checkpoint|perception of stimulus involved in morphogenesis checkpoint Any detection of stimulus that is involved in morphogenesis checkpoint. GO:0048667 cell morphogenesis involved in neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048667 neuron morphogenesis involved in differentiation The process in which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron. GO:1903820 signal transduction involved in mitotic cytokinesis checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903820 signaling cascade involved in mitotic cytokinesis checkpoint|signaling pathway involved in mitotic cytokinesis checkpoint|signalling cascade involved in mitotic cytokinesis checkpoint|signalling pathway involved in mitotic cytokinesis checkpoint Any signal transduction that is involved in a mitotic cytokinesis checkpoint. CHEBI:87584 N(2)-acyl-L-glutaminate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87584 GO:0048666 neuron development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048666 The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. GO:0048665 neuron fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048665 The process in which a cell becomes capable of differentiating autonomously into a neuron in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. GO:0048664 neuron fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048664 The process in which a cell becomes capable of differentiating autonomously into a neuron regardless of its environment; upon determination, the cell fate cannot be reversed. GO:0048663 neuron fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048663 neuron lineage restriction|neuronal lineage restriction The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron. GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034098 Cdc48p-Npl4p-Ufd1p AAA ATPase complex|p97-Ufd1-Npl4 complex A multiprotein ATPase complex required for the efficient dislocation of ER-lumenal degradation substrates, and their subsequent proteolysis by the proteasome. In budding yeast, this complex includes Cdc48p, Npl4p and Ufd1p proteins. In mammals, this complex includes a hexamer of VCP/p97 (a cytosolic ATPase) and trimers of each of its cofactors UFD1L and NPL4 (NPLOC4) (e.g. a 6:3:3 stoichiometry). CL:1001588 colon glandular cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001588 colon glandular cells Glandular cell of colon epithelium. Example: Goblet cells; enterocytes or absorptive cells; enteroendocrine and M cells. CL:1001587 uterine cervix glandular cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001587 cervix glandular cell|cervix, uterine glandular cell|cervix, uterine glandular cells Glandular cell of uterine cervix epithelium. GO:0034097 response to cytokine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034097 response to cytokine stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus. CL:1001586 mammary gland glandular cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001586 mammary glandular cell|breast glandular cell|breast glandular cells Glandular cell of mammary epithelium. Example: glandular cells of large and intermediate ducts, glandular cells in terminal ducts. GO:0034096 positive regulation of maintenance of meiotic sister chromatid cohesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034096 Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle. GO:0034095 negative regulation of maintenance of meiotic sister chromatid cohesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034095 Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle. GO:0034094 regulation of maintenance of meiotic sister chromatid cohesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034094 Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle. GO:0034093 positive regulation of maintenance of sister chromatid cohesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034093 Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained. GO:0034092 negative regulation of maintenance of sister chromatid cohesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034092 Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained. CL:1001582 lateral ventricle neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001582 lateral ventricle neuronal cell|lateral ventricle neural cell|lateral ventricle neuronal cells Neuron of lateral ventricle. CL:1001581 lateral ventricle glial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001581 lateral ventricle glial cells Glial cell of lateral ventricle. GO:0034091 regulation of maintenance of sister chromatid cohesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034091 Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained. CL:1001580 hippocampus glial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001580 hippocampus glial cells|hippocampus neuroglial cell|hippocampal glial cell Glial cell of hippocampus. PR:000011387 neuropeptide Y biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000011387 NPY A protein that is a translation product of the human NPY gene or a 1:1 ortholog thereof. GO:0034099 luminal surveillance complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034099 A multiprotein complex that recognizes ERAD-luminal misfolded substrates and brings them to the ubiquitination/extraction machinery. In yeast, this complex consists of Yos9p, Kar2p and Hrd3p proteins. GO:0048673 collateral sprouting of intact axon in response to injury biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048673 The process in which outgrowths develop from the axons of intact undamaged neurons as a result of injury to an axon. The collateral sprouts typically appear from undamaged axons in a tissue which has had part of its nerve supply removed, and they can often innervate successfully any cells that have lost some or all of their original synaptic input. GO:0048672 positive regulation of collateral sprouting biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048672 up regulation of collateral sprouting|upregulation of collateral sprouting|stimulation of collateral sprouting|up-regulation of collateral sprouting|activation of collateral sprouting Any process that activates or increases the frequency, rate or extent of collateral sprouting. GO:0048671 negative regulation of collateral sprouting biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048671 downregulation of collateral sprouting|down regulation of collateral sprouting|inhibition of collateral sprouting|down-regulation of collateral sprouting Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting. GO:1903839 positive regulation of mRNA 3'-UTR binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903839 activation of mRNA 3'-UTR binding|upregulation of mRNA 3' UTR binding|up-regulation of mRNA 3'-UTR binding|up regulation of mRNA 3' UTR binding|positive regulation of mRNA 3' UTR binding|activation of mRNA 3' UTR binding|upregulation of mRNA 3'-UTR binding|up-regulation of mRNA 3' UTR binding|up regulation of mRNA 3'-UTR binding Any process that activates or increases the frequency, rate or extent of mRNA 3'-UTR binding. GO:0048670 regulation of collateral sprouting biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048670 Any process that modulates the frequency, rate or extent of collateral sprouting. GO:1903838 negative regulation of mRNA 3'-UTR binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903838 down-regulation of mRNA 3'-UTR binding|inhibition of mRNA 3'-UTR binding|down regulation of mRNA 3' UTR binding|downregulation of mRNA 3' UTR binding|down-regulation of mRNA 3' UTR binding|negative regulation of mRNA 3' UTR binding|down regulation of mRNA 3'-UTR binding|downregulation of mRNA 3'-UTR binding|inhibition of mRNA 3' UTR binding Any process that stops, prevents or reduces the frequency, rate or extent of mRNA 3'-UTR binding. GO:1903837 regulation of mRNA 3'-UTR binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903837 regulation of mRNA 3' UTR binding Any process that modulates the frequency, rate or extent of mRNA 3'-UTR binding. GO:1903835 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1903835 GO:1903834 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1903834 GO:0034090 maintenance of meiotic sister chromatid cohesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034090 The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle. GO:1903833 positive regulation of cellular response to amino acid starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903833 upregulation of cellular response to amino acid starvation|up-regulation of cellular response to amino acid starvation|activation of cellular response to amino acid starvation|up regulation of cellular response to amino acid starvation Any process that activates or increases the frequency, rate or extent of cellular response to amino acid starvation. CHEBI:87571 6beta-hydroxyandrost-4-ene-3,17-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87571 GO:0048679 regulation of axon regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048679 Any process that modulates the frequency, rate or extent of axon regeneration. GO:1903832 regulation of cellular response to amino acid starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903832 Any process that modulates the frequency, rate or extent of cellular response to amino acid starvation. GO:0048678 response to axon injury biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048678 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an axon injury stimulus. GO:1903831 signal transduction involved in cellular response to ammonium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903831 signalling pathway involved in cellular response to ammonium ion|signaling pathway involved in cellular response to ammonium ion|signalling cascade involved in cellular response to ammonium ion|signaling cascade involved in cellular response to ammonium ion Any signal transduction that is involved in cellular response to ammonium ion. GO:0048677 axon extension involved in regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048677 Long distance growth of a single axon process involved in regeneration of the neuron. GO:1903830 magnesium ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903830 The directed movement of magnesium ion across a membrane. UBERON:0035016 tactile mechanoreceptor biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035016 contact receptor GO:0048676 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0048676 CL:1001579 cerebral cortex glial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001579 brain cortex glial cell|cerebral cortex glial cells|cerebrum cortex glial cell Glial cell of cerebral cortex. GO:0048675 axon extension biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048675 axon extension involved in development Long distance growth of a single axon process involved in cellular development. UBERON:0035018 thermoreceptor biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035018 thermoreceptor Cellular receptors which mediate the sense of temperature. Thermoreceptors in vertebrates are mostly located under the skin. In mammals there are separate types of thermoreceptors for cold and for warmth and NOCICEPTORS which detect cold or heat extreme enough to cause pain. UBERON:0035017 nociceptor biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035017 nociceptor|pain receptor Peripheral receptors for pain. Nociceptors include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli. All nociceptors are free nerve endings. GO:0048674 collateral sprouting of injured axon biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048674 The process resulting in reformation of a growth cone by the tip of an injured axon, or in collateral sprouting of the axon. Collateral sprouting is the process in which outgrowths develop from the shafts of existing axons. CL:1001578 vagina squamous cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001578 vaginal squamous epithelial cell|vaginal squamous cell|vagina squamous epithelial cells|vagina squamous epithelial cell Squamous cell of vaginal epithelium. GO:0034087 establishment of mitotic sister chromatid cohesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034087 The process in which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase during a mitotic cell cycle. GO:0034086 maintenance of sister chromatid cohesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034086 The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate. CL:1001575 uterine cervix squamous cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001575 uterine cervix squamous epithelial cells|cervix squamous epithelial cell|uterine cervix squamous epithelial cell|cervix, uterine squamous epithelial cells|cervix squamous cell Squamous cell of uterine cervix epithelium. GO:0034085 establishment of sister chromatid cohesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034085 The process in which the sister chromatids of a replicated chromosome become associated with each other during S phase. GO:0034084 steryl deacetylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034084 sterol deacetylase activity Catalysis of the hydrolysis of an acetyl group or groups from an acetylated sterol. GO:0097608 transverse flagellum biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097608 transverse cilium A motile cilium found in dinoflagellates. It coils around the cell and provides the forward thrust for motility. It is often contained in a furrow called the cingulum, and emerges from a flagellar pore located in the cingulum. GO:0034083 type III polyketide synthase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034083 type III PKS complex|type III polyketide synthase|type III PKS A polyketide synthase complex that consists of two identical ketosynthase polypeptides. CL:1001572 colon endothelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001572 colonic endothelial cell|colon endothelial cells A vascular endothelial cell found in colon blood vessels. GO:0034082 type II polyketide synthase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034082 type II PKS complex|type II polyketide synthase|type II PKS A polyketide synthase complex that consists of several different polypeptide chains, each of which catalyzes a single reaction. GO:0097607 obsolete negative regulation of nuclear envelope permeability biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097607 negative regulation of nuclear membrane permeability OBSOLETE. Any process that decreases the frequency, rate or extent of the passage or uptake of molecules by the nuclear envelope. GO:0034081 polyketide synthase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034081 PKS|PKS complex A protein complex that carries out enzymatic reactions involved in the biosynthesis of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones. CL:1001571 hippocampal pyramidal neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001571 hippocampus (CA) pyramidal cell|hippocampus (CA) pyramidal neuron A pyramidal neuron of the hippocampus. GO:0034080 CENP-A containing nucleosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034080 centromere specific nucleosome exchange|DNA replication-independent nucleosome assembly at centromere|CENP-A loading|centromere-specific histone exchange|CENP-A deposition|CENP-A containing nucleosome assembly at centromere|CenH3-containing nucleosome assembly at centromere|centromeric DNA replication-independent nucleosome assembly The formation of nucleosomes containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres, and the central core in modular centromeres. GO:0097609 longitudinal flagellum biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0097609 longitudinal cilium A motile cilium found in dinoflagellates. It trails the cell and acts as a steering rudder. It is often partially contained in a furrow called the sulcus, and emerges from a flagellar pore located in the sulcus. GO:0097604 temperature-gated cation channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097604 heat-activated cation channel activity|temperature-activated cation channel activity|temperature gated cation channel activity|temperature-dependent cation channel activity Enables the transmembrane transfer of a cation by a channel that opens in response to a temperature stimulus (e.g. exposure to a temperature range different than the optimal temperature for that organism). GO:0097603 temperature-gated ion channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097603 temperature gated ion channel activity|heat-activated ion channel activity|temperature-activated ion channel activity|temperature-dependent ion channel activity Enables the transmembrane transfer of an ion by a channel that opens in response to a temperature stimulus (e.g. exposure to a temperature range different than the optimal temperature for that organism). GO:0097606 obsolete positive regulation of nuclear envelope permeability biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097606 positive regulation of nuclear membrane permeability OBSOLETE. Any process that increases the frequency, rate or extent of the passage or uptake of molecules by the nuclear envelope. GO:0097605 obsolete regulation of nuclear envelope permeability biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097605 regulation of nuclear membrane permeability OBSOLETE. Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by the nuclear envelope. GO:0097600 exoxylanase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097600 A xylanase activity that acts on one of the ends of a xylan polymer which does not contain side chains. GO:0097602 cullin family protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0097602 cullin binding Interacting selectively and non-covalently with any member of the cullin family, hydrophobic proteins that act as scaffolds for ubiquitin ligases (E3). GO:0034089 establishment of meiotic sister chromatid cohesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034089 The process in which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase during a meiotic cell cycle. GO:0097601 retina blood vessel maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0097601 maintenance of retinal blood vessel|maintenance of retina blood vessel|maintenance of choriocapillaris A retina homeostatic process preventing the degeneration of a retina blood vessel. GO:0034088 maintenance of mitotic sister chromatid cohesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034088 mitotic cohesion stability The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle. UBERON:0011092 right pelvic girdle region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011092 right pelvic girdle A pelvic girdle region that is in the right side of a multicellular organism. GO:0048684 positive regulation of collateral sprouting of intact axon in response to injury biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048684 up regulation of collateral sprouting of intact axon in response to injury|activation of collateral sprouting of intact axon in response to injury|stimulation of collateral sprouting of intact axon in response to injury|up-regulation of collateral sprouting of intact axon in response to injury|upregulation of collateral sprouting of intact axon in response to injury Any process that activates, maintains or increases the rate of collateral sprouting of an intact axon as a result of injury to an axon. UBERON:0011091 skeleton of left pelvic girdle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011091 A skeleton of pelvic girdle that is part of a left pelvic girdle region. GO:0048683 regulation of collateral sprouting of intact axon in response to injury biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048683 Any process that modulates the frequency, rate or extent of collateral sprouting of an intact axon as a result of injury to an axon. GO:0048682 sprouting of injured axon biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048682 The process involved in sprouting of an injured axon. UBERON:0011090 skeleton of right pelvic girdle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011090 A skeleton of pelvic girdle that is part of a right pelvic girdle region. GO:0048681 negative regulation of axon regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048681 down regulation of axon regeneration|downregulation of axon regeneration|down-regulation of axon regeneration|inhibition of axon regeneration Any process that stops, prevents, or reduces the frequency, rate or extent of axon regeneration. UBERON:0011096 lacrimal nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011096 nervus lacrimalis The lacrimal nerve is the smallest of the three branches of the ophthalmic division of the trigeminal nerve. GO:1903849 positive regulation of aorta morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903849 up regulation of aorta morphogenesis|activation of aorta morphogenesis|up-regulation of aorta morphogenesis|upregulation of aorta morphogenesis Any process that activates or increases the frequency, rate or extent of aorta morphogenesis. GO:0048680 positive regulation of axon regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048680 upregulation of axon regeneration|up regulation of axon regeneration|activation of axon regeneration|stimulation of axon regeneration|up-regulation of axon regeneration Any process that activates, maintains or increases the rate of axon regeneration. UBERON:0011095 vertebra pre-cartilage condensation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011095 vertebral pre-cartilage condensation The pre-cartilaginous form of a vertebral element, a skeletal element that forms around the notochord and is part of the vertebral column. GO:1903848 negative regulation of aorta morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903848 down-regulation of aorta morphogenesis|inhibition of aorta morphogenesis|down regulation of aorta morphogenesis|downregulation of aorta morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of aorta morphogenesis. UBERON:0011094 vertebra cartilage element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011094 vertebral cartilage condensation The cartilaginous form of a vertebral element, a skeletal element that forms around the notochord and is part of the vertebral column. UBERON:0035021 right vagus X nerve trunk biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035021 trunk of right vagus|posterior vagus X nerve trunk|right vagus neural trunk GO:1903847 regulation of aorta morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903847 Any process that modulates the frequency, rate or extent of aorta morphogenesis. GO:1903846 positive regulation of cellular response to transforming growth factor beta stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903846 up regulation of cellular response to TGFbeta stimulus|activation of cellular response to TGFbeta stimulus|positive regulation of cellular response to TGFbeta stimulus|up-regulation of cellular response to TGF-beta stimulus|activation of cellular response to TGF-beta stimulus|upregulation of cellular response to transforming growth factor beta stimulus|positive regulation of cellular response to TGF-beta stimulus|up-regulation of cellular response to TGFbeta stimulus|up regulation of cellular response to transforming growth factor beta stimulus|up regulation of cellular response to TGF-beta stimulus|activation of cellular response to transforming growth factor beta stimulus|upregulation of cellular response to TGFbeta stimulus|upregulation of cellular response to TGF-beta stimulus|up-regulation of cellular response to transforming growth factor beta stimulus Any process that activates or increases the frequency, rate or extent of cellular response to transforming growth factor beta stimulus. UBERON:0035020 left vagus X nerve trunk biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035020 left vagus neural trunk|anterior vagus X nerve trunk|trunk of left vagus UBERON:0011093 left pelvic girdle region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011093 left pelvic girdle A pelvic girdle region that is in the left side of a multicellular organism. GO:1903845 negative regulation of cellular response to transforming growth factor beta stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903845 negative regulation of cellular response to TGFbeta stimulus|down-regulation of cellular response to TGFbeta stimulus|down regulation of cellular response to transforming growth factor beta stimulus|down-regulation of cellular response to TGF-beta stimulus|negative regulation of cellular response to TGF-beta stimulus|downregulation of cellular response to transforming growth factor beta stimulus|inhibition of cellular response to TGFbeta stimulus|downregulation of cellular response to TGF-beta stimulus|down-regulation of cellular response to transforming growth factor beta stimulus|down regulation of cellular response to TGF-beta stimulus|inhibition of cellular response to TGF-beta stimulus|down regulation of cellular response to TGFbeta stimulus|inhibition of cellular response to transforming growth factor beta stimulus|downregulation of cellular response to TGFbeta stimulus Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to transforming growth factor beta stimulus. GO:1903844 regulation of cellular response to transforming growth factor beta stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903844 regulation of cellular response to TGF-beta stimulus|regulation of cellular response to TGFbeta stimulus Any process that modulates the frequency, rate or extent of cellular response to transforming growth factor beta stimulus. GO:1903843 cellular response to arsenite ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903843 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite ion stimulus. GO:1903842 response to arsenite ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903842 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite ion stimulus. GO:0048689 formation of growth cone in injured axon biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048689 The formation of a growth cone in an injured axon. GO:0048688 negative regulation of sprouting of injured axon biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048688 down-regulation of sprouting of injured axon|inhibition of sprouting of injured axon|down regulation of sprouting of injured axon|downregulation of sprouting of injured axon Any process that stops, prevents, or reduces the frequency, rate or extent of sprouting of an injured axon. GO:1903841 cellular response to arsenite(3-) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903841 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite(3-) stimulus. GO:0048687 positive regulation of sprouting of injured axon biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048687 activation of sprouting of injured axon|stimulation of sprouting of injured axon|up-regulation of sprouting of injured axon|upregulation of sprouting of injured axon|up regulation of sprouting of injured axon Any process that activates, maintains or increases the rate of sprouting of an injured axon. GO:1903840 response to arsenite(3-) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903840 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite(3-) stimulus. GO:0048686 regulation of sprouting of injured axon biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048686 Any process that modulates the frequency, rate or extent of sprouting of an injured axon. GO:0048685 negative regulation of collateral sprouting of intact axon in response to injury biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048685 down-regulation of collateral sprouting of intact axon in response to injury|inhibition of collateral sprouting of intact axon in response to injury|down regulation of collateral sprouting of intact axon in response to injury|downregulation of collateral sprouting of intact axon in response to injury Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting of an intact axon as a result of injury to an axon. GO:0034076 cucurbitadienol synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034076 Catalysis of the reaction: oxidosqualene = cucurbitadienol. GO:0034075 arabidiol synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034075 EC:4.2.1.124|MetaCyc:RXN-9684|RHEA:31035 Catalysis of the reaction: oxidosqualene + H2O = arabidiol ((13R,14R,17E)-malabarica-17,21-diene-3beta,14-diol). GO:0034074 marneral synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034074 MetaCyc:RXN-9664|RHEA:31875 Catalysis of the reaction: oxidosqualene = marneral. GO:0034073 tetrahymanol cyclase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034073 Catalysis of the reaction: squalene = tetrahymanol. GO:0034072 squalene cyclase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034072 Catalysis of the reaction: squalene = triterpene. GO:0034071 aminoglycoside phosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034071 EC:2.7.1.- aminoglycoside kinase activity Catalysis of the reaction: ATP + aminoglycoside = ADP + phosphoaminoglycoside. GO:0034070 aminoglycoside 1-N-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034070 Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + 1-N-acetylaminoglycoside. This is acetylation of the 1-amino group of the central deoxystreptamine ring. GO:0034079 butanediol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034079 MetaCyc:P125-PWY butylene glycol biosynthesis|butylene glycol biosynthetic process|butanediol biosynthesis|butanediol anabolism|butanediol synthesis|butanediol formation The chemical reactions and pathways resulting in the formation of butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3. GO:0034078 butanediol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034078 butylene glycol catabolic process|butanediol degradation|butanediol breakdown|butanediol utilization|butanediol catabolism|butylene glycol catabolism The chemical reactions and pathways resulting in the breakdown of butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3. GO:0034077 butanediol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034077 butylene glycol metabolic process|butylene glycol metabolism|butanediol metabolism The chemical reactions and pathways involving butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3. GO:0048695 negative regulation of collateral sprouting of injured axon biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048695 downregulation of collateral sprouting of injured axon|down regulation of collateral sprouting of injured axon|inhibition of collateral sprouting of injured axon|down-regulation of collateral sprouting of injured axon Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting of an injured axon. GO:0048694 positive regulation of collateral sprouting of injured axon biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048694 up regulation of collateral sprouting of injured axon|upregulation of collateral sprouting of injured axon|stimulation of collateral sprouting of injured axon|up-regulation of collateral sprouting of injured axon|activation of collateral sprouting of injured axon Any process that activates, maintains or increases the rate of collateral sprouting of an injured axon. GO:0048693 regulation of collateral sprouting of injured axon biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048693 Any process that modulates the frequency, rate or extent of collateral sprouting of an injured axon. GO:0048692 negative regulation of axon extension involved in regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048692 inhibition of axon extension involved in regeneration|down regulation of axon extension involved in regeneration|downregulation of axon extension involved in regeneration|down-regulation of axon extension involved in regeneration Any process that stops, prevents, or reduces the frequency, rate or extent of axon extension involved in regeneration. UBERON:0011085 palatoquadrate arch biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011085 dorsal pharyngeal arch 1|palatoquadrate arch|upper pharyngeal jaw|dorsal visceral arch 1|upper pharyngeal jaw|dorsal visceral arch 1|dorsal mandibular arch|upper jaw The dorsal portion of the first pharyngeal arch, comprising the upper jaw[ZFIN,VHOG]. GO:0048691 positive regulation of axon extension involved in regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048691 up-regulation of axon extension involved in regeneration|upregulation of axon extension involved in regeneration|up regulation of axon extension involved in regeneration|activation of axon extension involved in regeneration|stimulation of axon extension involved in regeneration Any process that activates, maintains or increases the rate of axon extension involved in regeneration. GO:0048690 regulation of axon extension involved in regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048690 Any process that modulates the frequency, rate or extent of axon extension involved in regeneration. GO:1903859 regulation of dendrite extension biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903859 Any process that modulates the frequency, rate or extent of dendrite extension. GO:1903858 protein localization to old growing cell tip biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903858 protein localisation to old growing cell tip|protein localisation in old growing cell tip|protein localization in old growing cell tip A process in which a protein is transported to, or maintained in, a location within an old growing cell tip. GO:1903857 negative regulation of cytokinin dehydrogenase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903857 negative regulation of 6-N-dimethylallyladenine:acceptor oxidoreductase activity|down regulation of N6-dimethylallyladenine:acceptor oxidoreductase activity|down-regulation of 6-N-dimethylallyladenine:acceptor oxidoreductase activity|down regulation of cytokinin oxidase activity|inhibition of cytokinin dehydrogenase activity|inhibition of N6-dimethylallyladenine:acceptor oxidoreductase activity|inhibition of 6-N-dimethylallyladenine:acceptor oxidoreductase activity|inhibition of cytokinin oxidase activity|negative regulation of N6-dimethylallyladenine:(acceptor) oxidoreductase activity|down-regulation of N6-dimethylallyladenine:(acceptor) oxidoreductase activity|downregulation of N6-dimethylallyladenine:(acceptor) oxidoreductase activity|down-regulation of cytokinin dehydrogenase activity|negative regulation of N6-dimethylallyladenine:acceptor oxidoreductase activity|down regulation of 6-N-dimethylallyladenine:acceptor oxidoreductase activity|down-regulation of N6-dimethylallyladenine:acceptor oxidoreductase activity|down-regulation of cytokinin oxidase activity|negative regulation of cytokinin oxidase activity|down regulation of N6-dimethylallyladenine:(acceptor) oxidoreductase activity|downregulation of 6-N-dimethylallyladenine:acceptor oxidoreductase activity|inhibition of N6-dimethylallyladenine:(acceptor) oxidoreductase activity|downregulation of cytokinin dehydrogenase activity|downregulation of N6-dimethylallyladenine:acceptor oxidoreductase activity|downregulation of cytokinin oxidase activity|down regulation of cytokinin dehydrogenase activity Any process that stops, prevents or reduces the frequency, rate or extent of cytokinin dehydrogenase activity. GO:1903856 regulation of cytokinin dehydrogenase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903856 regulation of N6-dimethylallyladenine:(acceptor) oxidoreductase activity|regulation of 6-N-dimethylallyladenine:acceptor oxidoreductase activity|regulation of N6-dimethylallyladenine:acceptor oxidoreductase activity|regulation of cytokinin oxidase activity Any process that modulates the frequency, rate or extent of cytokinin dehydrogenase activity. UBERON:0035034 eyelid epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035034 An epithelium that is part of an eyelid [Automatically generated definition]. GO:1903855 positive regulation of stress response to copper ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903855 up-regulation of response to copper ion stress|upregulation of stress response to copper ion|upregulation of response to copper toxicity|upregulation of response to copper ion stress|up regulation of stress response to copper ion|up regulation of response to copper toxicity|positive regulation of response to copper toxicity|activation of stress response to copper ion|up regulation of response to copper ion stress|activation of response to copper toxicity|positive regulation of response to copper ion stress|activation of response to copper ion stress|up-regulation of stress response to copper ion|up-regulation of response to copper toxicity Any process that activates or increases the frequency, rate or extent of stress response to copper ion. UBERON:0011088 ligament of knee joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011088 knee joint ligament A ligament that is part of a knee joint. CHEBI:87593 15alpha-hydroxyestradiol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87593 GO:1903854 negative regulation of stress response to copper ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903854 inhibition of response to copper ion stress|down regulation of response to copper toxicity|down regulation of stress response to copper ion|downregulation of stress response to copper ion|downregulation of response to copper toxicity|down regulation of response to copper ion stress|downregulation of response to copper ion stress|down-regulation of response to copper toxicity|down-regulation of stress response to copper ion|negative regulation of response to copper toxicity|down-regulation of response to copper ion stress|negative regulation of response to copper ion stress|inhibition of stress response to copper ion|inhibition of response to copper toxicity Any process that stops, prevents or reduces the frequency, rate or extent of stress response to copper ion. UBERON:0035036 naris epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035036 An epithelium that is part of a naris [Automatically generated definition]. GO:1903853 regulation of stress response to copper ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903853 regulation of response to copper toxicity|regulation of response to copper ion stress|regulation of stress response to copper Any process that modulates the frequency, rate or extent of stress response to copper ion. GO:0048699 generation of neurons biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048699 neuron generation The process in which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons. CHEBI:87598 7alpha-hydroxyestradiol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87598 GO:1903852 positive regulation of cristae formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903852 upregulation of cristae formation|up regulation of cristae formation|activation of cristae formation|up-regulation of cristae formation Any process that activates or increases the frequency, rate or extent of cristae formation. UBERON:0035037 jaw epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035037 GO:0048698 negative regulation of collateral sprouting in absence of injury biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048698 down-regulation of collateral sprouting in the absence of injury|inhibition of collateral sprouting in the absence of injury|down regulation of collateral sprouting in the absence of injury|downregulation of collateral sprouting in the absence of injury Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting in the absence of injury. GO:1903851 negative regulation of cristae formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903851 down regulation of cristae formation|downregulation of cristae formation|down-regulation of cristae formation|inhibition of cristae formation Any process that stops, prevents or reduces the frequency, rate or extent of cristae formation. GO:0048697 positive regulation of collateral sprouting in absence of injury biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048697 up regulation of collateral sprouting in the absence of injury|activation of collateral sprouting in the absence of injury|stimulation of collateral sprouting in the absence of injury|up-regulation of collateral sprouting in the absence of injury|upregulation of collateral sprouting in the absence of injury Any process that activates or increases the frequency, rate or extent of collateral sprouting in the absence of injury. GO:1903850 regulation of cristae formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903850 Any process that modulates the frequency, rate or extent of cristae formation. GO:0048696 regulation of collateral sprouting in absence of injury biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0048696 Any process that modulates the frequency, rate or extent of collateral sprouting in the absence of injury. UBERON:0035039 rectal artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035039 hemorrhoidal artery CL:1001599 pancreas exocrine glandular cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001599 pancreas exocrine glandular cells|exocrine pancreas glandular cell Glandular cell of exocrine pancreas epithelium. Example: pancreatic acinar cell, glandular cells in pancreatic canaliculi, glandular cells in pancreatic ducts. GO:0034065 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0034065 GO:0034064 Tor2-Mei2-Ste11 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034064 A protein complex that contains the transcription factor Ste11 and the RNA binding protein Mei2; involved in regulation of conjugation in fission yeast. CL:1001598 small intestine glandular cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001598 small intestine glandular cells|small bowel glandular cell|small intestinal glandular cell A glandular cell found in the epithelium of the small intestine. Example: Enterocytes, Goblet cells, enteroendocrine cells; Paneth cells; M cells; Somatostatin-secreting Cells (D-cells) . CL:1001597 seminal vesicle glandular cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001597 seminal vesicle glandular cells Glandular cell of seminal vesicle epithelium. GO:0034063 stress granule assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034063 SG assembly The aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule. GO:0034062 5'-3' RNA polymerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034062 Reactome:R-HSA-6786881|Reactome:R-HSA-5696807 transcriptase|ribonucleic polymerase activity|RNA nucleotidyltransferase activity|ribonucleate nucleotidyltransferase activity|RNA transcriptase activity|ribonucleate polymerase activity|ribonucleic acid nucleotidyltransferase|ribonucleic transcriptase activity|RNA polymerase activity|C ribonucleic acid formation factors|ribonucleic acid transcriptase activity|C RNA formation factors|ribonucleic acid polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template, via extension of the 3'-end. CL:1001596 salivary gland glandular cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001596 salivary gland glandular cells Glandular cell of salivary gland. Example: Serous cells, mucous cells, cuboidal epithelial cells of the intercalated ducts, simple cuboidal epithelium of the striated ducts, epithelial cells of excretory ducts. GO:0034061 DNA polymerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034061 deoxynucleate polymerase activity|deoxyribonucleic acid polymerase activity|deoxyribonucleic polymerase activity|DNA nucleotidyltransferase activity|deoxyribonucleate nucleotidyltransferase activity Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a nucleic acid template and a 3'hydroxyl group. GO:0034060 cyanelle stroma biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034060 The space enclosed by the double membrane of a cyanelle. CL:1001593 parathyroid glandular cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001593 parathyroid gland glandular cells|parathyroid gland glandular cell Glandular cell of parathyroid epithelium. Example: Parathyroid chief cell and parathyroid oxyphil cells. CL:1001592 gall bladder glandular cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001592 gallbladder glandular cell|gallbladder glandular cells|gall bladder glandular cells Glandular cell of gall bladder epithelium. CL:1001591 oviduct glandular cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001591 fallopian tube glandular cell|uterine tube glandular cell|fallopian tube glandular cells Glandular cell of oviduct epithelium. Example: peg cells, ciliated cells. CL:1001590 epididymis glandular cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1001590 epididymis glandular cells|epididymal glandular cell Glandular cell of epididymal epithelium. PR:000011374 atrial natriuretic factor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000011374 NPPA|CDD-ANF|atrial natriuretic peptide|ANP|PND|prepronatriodilatin|ANF A protein that is a translation product of the human NPPA gene or a 1:1 ortholog thereof. PO:0025545 anther wall tapetum cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025545 célula de la pared del tapete de la antera (Spanish, exact)|葯壁絨毯細胞 (Japanese, exact)|anther wall tapetal cell (exact) A microsporangium tapetum cell (PO:0025544) that is part of the anther wall tapetum (PO:0009071). GO:0034069 aminoglycoside N-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034069 kanamycin acetyltransferase activity Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + N-acetylaminoglycoside. GO:0034068 aminoglycoside nucleotidyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0034068 streptomycin adenylylase activity|streptomycin adenyltransferase activity|streptomycin adenylate synthetase activity|aminoglycoside adenylyltransferase activity|streptomycin-spectinomycin adenylyltransferase activity|streptomycin adenylyltransferase activity Catalysis of the reaction: nucleoside triphosphate + aminoglycoside = diphosphate + nucleotidylaminoglycoside. PO:0025544 microsporangium tapetum cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025544 célula del tapete del microsporangio (Spanish, exact)|小胞子嚢タペート細胞 (Japanese, exact)|microsporangium tapetal cell (exact) A tapetum cell (PO:0025543) that is part of a microsporangium tapetum (PO:0025314). GO:0034067 protein localization to Golgi apparatus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0034067 establishment of protein localization in Golgi|protein localization in Golgi apparatus|establishment of protein localization to Golgi apparatus|establishment of protein localization to Golgi|protein localisation in Golgi apparatus|protein-Golgi targeting|protein targeting to Golgi|establishment of protein localisation to Golgi A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus. PO:0025543 tapetum cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025543 tapetal cell (exact)|célula del tapete (Spanish, exact)|タペート細胞 (Japanese, exact) A native plant cell (PO:0025606) that is part of the tapetum (PO:0025313). GO:0034066 Ric1-Rgp1 guanyl-nucleotide exchange factor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0034066 IntAct:EBI-9517136 Ric1p-Rgp1p complex A protein complex that acts as a nucleotide exchange factor for the GTPase Ypt6p, and is required for fusion of endosome-derived vesicles with the Golgi. NCBITaxon:2058949 Dictyosteliales organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_2058949 GO:0102870 7-hydroxyflavone-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102870 MetaCyc:RXN-8355 Catalysis of the reaction: UDP-alpha-D-glucose + 7-hydroxyflavone <=> 7-O-beta-D-glucosyl-7-hydroxyflavone + UDP + H+. GO:0102872 1-16:0-2-18:2-phosphatidylcholine desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102872 EC:1.14.19.25|MetaCyc:RXN-8361 Catalysis of the reaction: 1-palmitoyl-2-linoleoyl-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-16:0-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor. GO:0102871 1-16:0-2-18:1-phosphatidylcholine desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102871 EC:1.14.19.22|MetaCyc:RXN-8360 Catalysis of the reaction: 1-16:0-2-18:1-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-palmitoyl-2-linoleoyl-phosphatidylcholine + 2 H2O + an oxidized electron acceptor. GO:0102874 1-16:0-2-18:2-digalactosyldiacylglycerol desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102874 EC:1.14.19.35|MetaCyc:RXN-8365 Catalysis of the reaction: 1-16:0-2-18:2-digalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-16:0-2-18:3-digalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. GO:0102873 1-18:1-2-16:0-digalactosyldiacylglycerol desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102873 EC:1.14.19.23|MetaCyc:RXN-8363 Catalysis of the reaction: 1-18:1-2-16:0-digalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-16:0-digalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. GO:0102876 psoralen synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102876 RHEA:19281|EC:1.14.14.141|MetaCyc:RXN-8386 Catalysis of the reaction: (+)-marmesin + NADPH + H+ + O2 <=> psoralen + NADP + acetone + 2 H2O. GO:0102875 1-18:2-2-18:2-monogalactosyldiacylglycerol desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102875 EC:1.14.19.35|MetaCyc:RXN-8366 Catalysis of the reaction: 1-18:2-2-18:2-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-18:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. CHEBI:18918 1,3-dichloropropene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18918 GO:0102878 (+)-alpha-barbatene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102878 MetaCyc:RXN-8417|EC:4.2.3.69|RHEA:29499 Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (+)-alpha-barbatene + diphosphoric acid. CHEBI:18917 1,3-dichloropropan-2-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18917 GO:0102877 alpha-copaene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102877 MetaCyc:RXN-8416|RHEA:33991|EC:4.2.3.133 Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> alpha-copaene + diphosphoric acid. GO:0102879 (+)-thujopsene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102879 MetaCyc:RXN-8418|EC:4.2.3.79|RHEA:30375 Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (+)-thujopsene + diphosphoric acid. CHEBI:18913 (1->3)-alpha-D-mannooligosaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18913 GO:0102881 (+)-beta-barbatene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102881 MetaCyc:RXN-8421 Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (+)-beta-barbatene + diphosphoric acid. GO:0102880 isobazzanene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102880 MetaCyc:RXN-8419 Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> isobazzanene + diphosphoric acid. GO:0102883 (+)-beta-chamigrene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102883 EC:4.2.3.78|MetaCyc:RXN-8424|RHEA:30379 Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (+)-beta-chamigrene + diphosphoric acid. GO:0102882 beta-acoradiene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102882 MetaCyc:RXN-8423 Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> beta-acoradiene + diphosphoric acid. GO:0102885 alpha-cuprenene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102885 RHEA:32027|EC:4.2.3.95|MetaCyc:RXN-8426 Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (-)-alpha-cuprenene + diphosphoric acid. GO:0102884 alpha-zingiberene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102884 EC:4.2.3.65|RHEA:28643|MetaCyc:RXN-8425 Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> zingiberene + diphosphoric acid. GO:0102887 beta-sesquiphellandrene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102887 MetaCyc:RXN-8430|RHEA:32699|EC:4.2.3.123 Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> beta-sesquiphellandrene + diphosphoric acid. GO:0102886 alpha-chamigrene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102886 MetaCyc:RXN-8428 Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> alpha-chamigrene + diphosphoric acid. GO:0102889 beta-elemene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102889 MetaCyc:RXN-8432 Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> beta-elemene + diphosphoric acid. GO:0102888 delta-cuprenene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102888 MetaCyc:RXN-8431 Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> delta-cuprenene + diphosphoric acid. CHEBI:18904 (3R,6R)-1,3,4,6-tetrachlorocyclohexa-1,4-diene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18904 GO:0102890 naringenin chalcone 4'-O-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102890 MetaCyc:RXN-8453|RHEA:34291|EC:2.4.1.286 Catalysis of the reaction: UDP-alpha-D-glucose + 2',4,4',6'-tetrahydroxychalcone <=> UDP + 2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside + H+. GO:0102892 betanidin 5-O-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102892 MetaCyc:RXN-8479 Catalysis of the reaction: UDP-alpha-D-glucose + betanidin <=> H+ + betanin + UDP. GO:0102891 2'4'6'34-pentahydroxychalcone 4'-O-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102891 MetaCyc:RXN-8455|RHEA:34295|EC:2.4.1.286 Catalysis of the reaction: UDP-alpha-D-glucose + 2',3,4,4',6'-pentahydroxychalcone <=> H+ + 2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside + UDP. GO:0102894 UDPG:cyclo-DOPA 5-O-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102894 MetaCyc:RXN-8481 Catalysis of the reaction: UDP-alpha-D-glucose + leucodopachrome <=> H+ + cyclo-dopa 5-O-glucoside + UDP. GO:0102893 betanidin 6-O-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102893 MetaCyc:RXN-8480 Catalysis of the reaction: UDP-alpha-D-glucose + betanidin <=> H+ + gomphrenin I + UDP. GO:0102896 colnelenate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102896 MetaCyc:RXN-8498|RHEA:28178 Catalysis of the reaction: (10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoate <=> colnelenate + H2O. GO:0102895 colneleate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102895 MetaCyc:RXN-8496|EC:4.2.1.121|RHEA:28174 Catalysis of the reaction: 9(S)-HPODE <=> colneleate + H2O. GO:0102898 levopimaradienol hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102898 MetaCyc:RXN-8517 Catalysis of the reaction: H+ + levopimaradienol + NADPH + O2 <=> levopiramadiene-diol + NADP + H2O. GO:0102897 abietadienal hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102897 RHEA:56928|MetaCyc:RXN-8510 Catalysis of the reaction: abietal + NADPH + O2 <=> abietate + NADP + H2O. GO:0102899 dehydroabietadienol hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102899 MetaCyc:RXN-8532 Catalysis of the reaction: H+ + dehydroabietadienol + NADPH + O2 <=> dehydroabietadiene-diol + NADP + H2O. GO:0102830 verbascose synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102830 MetaCyc:RXN-8286 Catalysis of the reaction: 2 stachyose <=> verbascose + raffinose. GO:0102832 verbascose galactinol:ajugose galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102832 MetaCyc:RXN-8288 Catalysis of the reaction: verbascose + alpha-D-galactosyl-(1->3)-1D-myo-inositol <=> ajugose + myo-inositol. GO:0102831 stachyose synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102831 MetaCyc:RXN-8287 Catalysis of the reaction: 2 raffinose <=> stachyose + sucrose. GO:0102834 1-18:1-2-16:0-monogalactosyldiacylglycerol acyl-lipid omega-6 desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102834 EC:1.14.19.23|MetaCyc:RXN-8294 Catalysis of the reaction: 1-18:1-2-16:0-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-16:0-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. GO:0102833 sequoyitol galactinol:D-galactosylononitol galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102833 MetaCyc:RXN-8292 Catalysis of the reaction: 1D-5-O-methyl-myo-inositol + alpha-D-galactosyl-(1->3)-1D-myo-inositol <=> D-galactosylononitol + myo-inositol. GO:0102836 1-18:1-2-16:1-monogalactosyldiacylglyceroldesaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102836 EC:1.14.19.23|MetaCyc:RXN-8296 Catalysis of the reaction: 1-18:1-2-16:1-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-16:1-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. GO:0102835 1-18:2-2-16:0-monogalactosyldiacylglycerol desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102835 EC:1.14.19.35|MetaCyc:RXN-8295 Catalysis of the reaction: 1-18:2-2-16:0-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:0-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. GO:0102838 1-18:1-2-16:2-monogalactosyldiacylglycerol desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102838 EC:1.14.19.23|MetaCyc:RXN-8298 Catalysis of the reaction: 1-18:1-2-16:2-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. GO:0102837 1-18:2-2-16:1-monogalactosyldiacylglycerol desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102837 EC:1.14.19.35|MetaCyc:RXN-8297 Catalysis of the reaction: 1-18:2-2-16:1-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:1-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. GO:0102839 1-18:2-2-16:2-monogalactosyldiacylglycerol desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102839 EC:1.14.19.35|MetaCyc:RXN-8299 Catalysis of the reaction: 1-18:2-2-16:2-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. GO:0102841 1-18:1-2-16:2-monogalactosyldiacylglycerol synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102841 EC:1.14.19.23|MetaCyc:RXN-8302 Catalysis of the reaction: 1-18:1-2-16:1-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:1-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. GO:0102840 1-18:2-2-16:3-monogalactosyldiacylglycerol desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102840 MetaCyc:RXN-8301|EC:1.14.19.35 Catalysis of the reaction: 1-18:2-2-16:3-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:3-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. GO:0102843 1-18:2-2-16:0-monogalactosyldiacylglycerol desaturase activity (SN2-16:1 forming) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102843 MetaCyc:RXN-8304|EC:1.14.19.42|RHEA:46756 Catalysis of the reaction: 1-18:2-2-16:0-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor = 1-18:2-2-16:1-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. GO:0102842 1-18:1-2-16:2-monogalactosyldiacylglycerol desaturase activity (SN2-16:3 forming) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102842 MetaCyc:RXN-8303|RHEA:46412|EC:1.14.19.35 Catalysis of the reaction: 1-18:1-2-16:2-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor = 1-18:1-2-16:3-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. GO:0102845 1-18:3-2-16:0-monogalactosyldiacylglycerol desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102845 MetaCyc:RXN-8307 Catalysis of the reaction: 1-18:3-2-16:0-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:1-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. GO:0102844 1-18:2-2-16:1-monogalactosyldiacylglycerol desaturase activity (SN2-16:2 forming) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102844 EC:1.14.19.23|MetaCyc:RXN-8305 Catalysis of the reaction: 1-18:2-2-16:1-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor = 1-18:2-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. GO:0102847 1-18:3-2-16:2-monogalactosyldiacylglycerol desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102847 MetaCyc:RXN-8309 Catalysis of the reaction: 1-18:3-2-16:2-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:3-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. GO:0102846 1-18:3-2-16:1-monogalactosyldiacylglycerol desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102846 MetaCyc:RXN-8308 Catalysis of the reaction: 1-18:3-2-16:1-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. GO:0102849 1-18:2-2-18:3-digalactosyldiacylglycerol desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102849 EC:1.14.19.35|MetaCyc:RXN-8314 Catalysis of the reaction: 1-18:2-2-18:3-digalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-18:3-digalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. GO:0102848 1-18:2-2-18:2-digalactosyldiacylglycerol desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102848 EC:1.14.19.35|MetaCyc:RXN-8310 Catalysis of the reaction: 1-18:2-2-18:2-digalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-18:2-digalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. CHEBI:147369 glucotetraose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_147369 GO:0004385 guanylate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004385 EC:2.7.4.8|Reactome:R-HSA-110133|RHEA:20780|MetaCyc:GUANYL-KIN-RXN|Reactome:R-HSA-73788 ATP:GMP phosphotransferase activity|guanosine monophosphate kinase activity|membrane-associated guanylate kinase|deoxyguanylate kinase activity|ATP:(d)GMP phosphotransferase activity|5'-GMP kinase activity|GMP kinase activity Catalysis of the reaction: ATP + GMP = ADP + GDP. GO:0102850 1-18:1-2-16:0-phosphatidylglycerol omega-6 desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102850 MetaCyc:RXN-8316|EC:1.14.19.23|RHEA:46376 Catalysis of the reaction: 1-[(9Z)-octadec-9-enoyl]-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) + O2 + a reduced electron acceptor <=> 1-18:2-2-16:0-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor. GO:0004384 obsolete membrane-associated guanylate kinase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004384 MAGUK|membrane-associated guanylate kinase OBSOLETE. Catalysis of the reaction: ATP + GMP = ADP + GDP, associated with the cell membrane. GO:0102852 1-18:3-2-16:0-phosphatidylglycerol desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102852 MetaCyc:RXN-8319 Catalysis of the reaction: 1-18:3-2-16:0-phosphatidylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-trans-16:1-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor. GO:0004386 helicase activity biolink:MolecularActivity go-plus goslim_yeast|goslim_candida|goslim_pir|goslim_aspergillus|goslim_generic|goslim_chembl http://purl.obolibrary.org/obo/GO_0004386 Reactome:R-HSA-5686410|Reactome:R-HSA-169468|Reactome:R-HSA-169461|Reactome:R-HSA-5690996 ATP-dependent helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix. GO:0102851 1-18:2-2-16:0-phosphatidylglycerol desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102851 MetaCyc:RXN-8318|EC:1.14.19.43 Catalysis of the reaction: 1-18:2-2-16:0-phosphatidylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-trans-16:1-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor. GO:0004381 fucosylgalactoside 3-alpha-galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004381 RHEA:14349|MetaCyc:2.4.1.37-RXN|Reactome:R-HSA-9033961|EC:2.4.1.37|Reactome:R-HSA-9034053 UDPgalactose:alpha-L-fucosyl-(1,2)-D-galactoside 3-alpha-D-galactosyltransferase activity|UDPgalactose:O-alpha-L-fucosyl(1->2)D-galactose alpha-D-galactosyltransferase activity|histo-blood substance beta-dependent galactosyltransferase activity|glycoprotein-fucosylgalactoside alpha-galactosyltransferase activity|UDPgalactose:glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose 3-alpha-D-galactosyltransferase activity|[blood group substance] alpha-galactosyltransferase activity|B transferase activity|UDPgalactose:alpha-L-fucosyl-(1->2)-D-galactoside 3-alpha-D-galactosyltransferase activity|blood-group substance beta-dependent galactosyltransferase activity|histo-blood substance B-dependent galactosyltransferase activity|UDP-galactose:alpha-L-fucosyl-(1,2)-D-galactoside 3-alpha-D-galactosyltransferase activity|fucosylglycoprotein 3-alpha-galactosyltransferase activity|UDP-galactose:alpha-L-fucosyl-(1->2)-D-galactoside 3-alpha-D-galactosyltransferase activity|blood-group substance B-dependent galactosyltransferase activity|histo-blood group B transferase activity|UDPgalactose:O-alpha-L-fucosyl(1,2)D-galactose alpha-D-galactosyltransferase activity Catalysis of the reaction: UDP-galactose + glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose = UDP + glycoprotein-alpha-D-galactosyl-(1,3)-(alpha-L-fucosyl-(1,2))-D-galactose. GO:0102854 1-18:2-2-18:1-phosphatidylcholine desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102854 MetaCyc:RXN-8321 Catalysis of the reaction: 1-18:2-2-18:1-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-18:3-2-18:1-phosphatidylcholine + 2 H2O + an oxidized electron acceptor. GO:0004380 glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004380 EC:2.4.1.40|RHEA:19021|Reactome:R-HSA-9034042|Reactome:R-HSA-9033959|MetaCyc:2.4.1.40-RXN fucosylgalactose alpha-N-acetylgalactosaminyltransferase activity|UDP-N-acetyl-D-galactosamine:alpha-L-fucosyl-1,2-D-galactose 3-N-acetyl-D-galactosaminyltransferase activity|A transferase activity|blood-group substance A-dependent acetylgalactosaminyltransferase activity|histo-blood group A acetylgalactosaminyltransferase activity|UDP-N-acetyl-D-galactosamine:glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose 3-N-acetyl-D-galactosaminyltransferase activity|blood-group substance alpha-acetyltransferase activity|histo-blood group A glycosyltransferase (Fucalpha1->2Galalpha1->3-N-acetylgalactosaminyltransferase)|fucosylgalactose acetylgalactosaminyltransferase activity|alpha-3-N-acetylgalactosaminyltransferase activity|UDP-GalNAc:Fucalpha1->2Galalpha1->3-N-acetylgalactosaminyltransferase activity|fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase activity|A-transferase activity|histo-blood group A transferase activity Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose = UDP + glycoprotein-N-acetyl-alpha-D-galactosaminyl-(1,3)-(alpha-L-fucosyl-(1,2))-D-galactose. GO:0102853 1-18:1-2-18:1-sn-glycerol-3-phosphocholine desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102853 MetaCyc:RXN-8320 Catalysis of the reaction: 1-18:1-2-18:1-sn-glycerol-3-phosphocholine + O2 + a reduced electron acceptor <=> 1-18:2-2-18:1-phosphatidylcholine + 2 H2O + an oxidized electron acceptor. GO:0102856 1-18:2-2-18:2-sn-glycerol-3-phosphocholine desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102856 EC:1.14.19.25|MetaCyc:RXN-8323 Catalysis of the reaction: 1-18:2-2-18:2-sn-glycerol-3-phosphocholine + O2 + a reduced electron acceptor <=> 1-18:3-2-18:2-phosphatidylcholine + 2 H2O + an oxidized electron acceptor. GO:0004383 guanylate cyclase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004383 RHEA:13665|MetaCyc:GUANYLCYC-RXN|EC:4.6.1.2|Reactome:R-HSA-74885|Reactome:R-HSA-392152 GTP diphosphate-lyase (cyclizing) activity|receptor guanylate cyclase activity|guanylyl cyclase activity|guanyl cyclase activity|GTP diphosphate-lyase (cyclizing; 3',5'-cyclic-GMP-forming) activity Catalysis of the reaction: GTP = 3',5'-cyclic GMP + diphosphate. GO:0102855 1-18:1-2-18:2-phosphatidylcholine desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102855 EC:1.14.19.22|MetaCyc:RXN-8322|RHEA:46332 Catalysis of the reaction: 1-18:1-2-18:2-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-18:2-2-18:2-sn-glycerol-3-phosphocholine + 2 H2O + an oxidized electron acceptor. GO:0004382 guanosine-diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004382 RHEA:22156|EC:3.6.1.42|MetaCyc:GUANOSINE-DIPHOSPHATASE-RXN GDP phosphohydrolase activity|guanosine 5'-diphosphatase activity|guanosine diphosphatase activity|GDPase activity Catalysis of the reaction: GDP + H2O = GMP + phosphate. GO:0102858 1-18:2-2-18:3-phosphatidylcholine desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102858 MetaCyc:RXN-8325 Catalysis of the reaction: 1-18:2-2-18:3-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-18:3-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor. GO:0102857 1-18:1-2-18:3-phosphatidylcholinedesaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102857 EC:1.14.19.22|MetaCyc:RXN-8324 Catalysis of the reaction: 1-18:1-2-18:3-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-18:2-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor. GO:0102859 1-18:1-2-18:2-phosphatidylcholine desaturase activity (SN2-18:3 forming) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102859 EC:1.14.19.25|MetaCyc:RXN-8326|RHEA:46404 Catalysis of the reaction: 1-18:1-2-18:2-phosphatidylcholine + O2 + a reduced electron acceptor = 1-18:1-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor. GO:0004399 histidinol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004399 MetaCyc:HISTOLDEHYD-RXN|EC:1.1.1.23|MetaCyc:HISTALDEHYD-RXN|RHEA:20641 Catalysis of the reaction: L-histidinol + NAD+ = L-histidine + NADH + H+. GO:0004396 hexokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004396 RHEA:22740|EC:2.7.1.1|MetaCyc:HEXOKINASE-RXN ATP:D-hexose 6-phosphotransferase activity|hexokinase type III activity|hexokinase type I activity|glucose ATP phosphotransferase activity|hexokinase type IV|ATP-dependent hexokinase activity|hexokinase type IV glucokinase activity|hexokinase (phosphorylating)|hexokinase type IV (glucokinase) activity|hexokinase type II activity|hexokinase D Catalysis of the reaction: ATP + D-hexose = ADP + D-hexose 6-phosphate. GO:0102861 1-18:2-2-18:1-phosphatidylcholine desaturase activity (SN2-18:2 forming) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102861 MetaCyc:RXN-8328|EC:1.14.19.22 Catalysis of the reaction: 1-18:2-2-18:1-phosphatidylcholine + O2 + a reduced electron acceptor = 1-18:2-2-18:2-sn-glycerol-3-phosphocholine + 2 H2O + an oxidized electron acceptor. GO:0004395 hexaprenyldihydroxybenzoate methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004395 MetaCyc:2.1.1.114-RXN|RHEA:14121|EC:2.1.1.114 S-adenosyl-L-methionine:3-hexaprenyl-4,5-dihydroxylate O-methyltransferase activity|DHHB methyltransferase activity|3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase activity|dihydroxyhexaprenylbenzoate methyltransferase activity|DHHB-Mt activity Catalysis of the reaction: S-adenosyl-L-methionine + 3-hexaprenyl-4,5-dihydroxybenzoate = S-adenosyl-L-homocysteine + 3-hexaprenyl-4-hydroxy-5-methoxybenzoate. GO:0102860 1-18:1-2-18:2-phosphatidylcholine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102860 MetaCyc:RXN-8327|EC:1.14.19.22 Catalysis of the reaction: 1-18:1-2-18:1-sn-glycerol-3-phosphocholine + O2 + a reduced electron acceptor <=> 1-18:1-2-18:2-phosphatidylcholine + 2 H2O + an oxidized electron acceptor. GO:0102863 1-18:3-2-18:1-phosphatidylcholine desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102863 MetaCyc:RXN-8330 Catalysis of the reaction: 1-18:3-2-18:1-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-18:3-2-18:2-phosphatidylcholine + 2 H2O + an oxidized electron acceptor. GO:0004398 histidine decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004398 Reactome:R-HSA-977301|EC:4.1.1.22|RHEA:20840|MetaCyc:HISTIDINE-DECARBOXYLASE-RXN L-histidine carboxy-lyase activity|L-histidine carboxy-lyase (histamine-forming)|L-histidine decarboxylase activity Catalysis of the reaction: L-histidine = histamine + CO2. GO:0102862 1-18:2-2-18:2-sn-glycerol-3-phosphocholine desaturase activity (SN2-18:3 forming) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102862 MetaCyc:RXN-8329|EC:1.14.19.25 Catalysis of the reaction: 1-18:2-2-18:2-sn-glycerol-3-phosphocholine + O2 + a reduced electron acceptor = 1-18:2-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor. GO:0004397 histidine ammonia-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004397 Reactome:R-HSA-70899|MetaCyc:HISTIDINE-AMMONIA-LYASE-RXN|RHEA:21232|EC:4.3.1.3 histidinase activity|L-histidine ammonia-lyase (urocanate-forming)|L-histidine ammonia-lyase activity|histidine alpha-deaminase activity|histidase activity Catalysis of the reaction: L-histidine = urocanate + NH3. GO:0004392 heme oxygenase (decyclizing) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004392 Reactome:R-HSA-189398|RHEA:21764|MetaCyc:HEME-OXYGENASE-DECYCLIZING-RXN|EC:1.14.14.18 haem oxygenase (decyclizing) activity|heme oxidase activity|heme oxygenase activity|ORP33 proteins|haem oxidase activity|haem oxygenase activity|heme,hydrogen-donor:oxygen oxidoreductase (alpha-methene-oxidizing, hydroxylating) Catalysis of the reaction: heme + 3 donor-H2 + 3 O2 = biliverdin + Fe2+ + CO + 3 acceptor + 3 H2O. GO:0102865 Delta6-acyl-lipid desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102865 MetaCyc:RXN-8343 Catalysis of the reaction: O2 + a lipid linoleoyl group + a reduced electron acceptor <=> 2 H2O + a lipid gamma-linolenoyl group + an oxidized electron acceptor. GO:0102864 1-18:3-2-18:2-phosphatidylcholine desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102864 MetaCyc:RXN-8331 Catalysis of the reaction: 1-18:3-2-18:2-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-18:3-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor. GO:0102867 molybdenum cofactor sulfurtransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102867 RHEA:42636|EC:2.8.1.9|MetaCyc:RXN-8351 Catalysis of the reaction: 2 H+ + MoO2-molybdopterin cofactor(2-) + L-cysteine <=> thio-molybdenum cofactor + L-alanine + H2O. GO:0004394 heparan sulfate 2-O-sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004394 Reactome:R-HSA-2076508|EC:2.8.2.- heparin-sulphate 2-sulphotransferase activity|heparan-sulfate 2-O-sulphotransferase activity|heparin 2-sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + heparan sulfate 2-O-sulfate; results in 2-O-sulfation of iduronic acid residues in heparan sulfate. GO:0004393 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004393 GO:0102866 di-homo-gamma-linolenate Delta5 desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102866 RHEA:46260|MetaCyc:RXN-8346 Catalysis of the reaction: all-cis-icosa-8,11,14-trienoate + O2 + a reduced electron acceptor <=> arachidonate + 2 H2O + an oxidized electron acceptor. GO:0102869 6-hydroxyflavone-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102869 MetaCyc:RXN-8354 Catalysis of the reaction: UDP-alpha-D-glucose + 6-hydroxyflavone <=> 6-O-beta-D-glucosyl-6-hydroxyflavone + UDP + H+. GO:0102868 24-epi-campsterol desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102868 MetaCyc:RXN-8352 Catalysis of the reaction: 24-epi-campesterol + NADPH + H+ + O2 <=> brassicasterol + NADP + 2 H2O. CHEBI:28325 (S)-3-hydroxydecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28325 CHEBI:28328 D-galactosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28328 GO:0043971 histone H3-K18 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043971 histone H3K18 acetylation|histone H3 acetylation at K18 The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 18 of the histone. GO:0043970 histone H3-K9 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043970 histone H3 acetylation at K9|histone H3K9 acetylation The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 9 of the histone. GO:0043973 histone H3-K4 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043973 histone H3 acetylation at K4|histone H3K4 acetylation The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 4 of the histone. CHEBI:28324 11-deoxycortisol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28324 CHEBI:28323 3,4-dihydroxycinnamaldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28323 GO:0043972 histone H3-K23 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043972 histone H3K23 acetylation|histone H3 acetylation at K23 The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 23 of the histone. CHEBI:228 (4R,7R)-4-isopropenyl-7-methyloxepan-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_228 CHEBI:77292 1-(1Z)-hexadecenyl-2-arachidonoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77292 GO:0043979 histone H2B-K5 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043979 histone H2B acetylation at K5 The modification of histone H2B by the addition of an acetyl group to a lysine residue at position 5 of the histone. GO:0043978 histone H2A-K9 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043978 histone H2A acetylation at K9 The modification of histone H2A by the addition of an acetyl group to a lysine residue at position 9 of the histone. CHEBI:77291 1-(Z)-alk-1-enyl-2-oleoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77291 CHEBI:77290 1-(Z)-alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77290 CHEBI:77296 1-(Z)-alk-1-enyl-2-acyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77296 CHEBI:43967 N(2),N(2)-dimethylguanosine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_43967 GO:0043975 histone H3-K36 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043975 histone H3K36 acetylation|histone H3 acetylation at K36 The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 36 of the histone. CHEBI:227 (-)-cis-carveol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_227 GO:0043974 histone H3-K27 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043974 histone H3K27 acetylation|histone H3 acetylation at K27 The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 27 of the histone. CHEBI:43966 melagatran biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_43966 CHEBI:77295 1-(Z)-alk-1-enyl-2-arachidonoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77295 GO:0043977 histone H2A-K5 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043977 histone H2A acetylation at K5 The modification of histone H2A by the addition of an acetyl group to a lysine residue at position 5 of the histone. CHEBI:77294 1-(Z)-alk-1-enyl-2-oleoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77294 CHEBI:77293 (E)-2,3-didehydropristanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77293 GO:0043976 histone H3-K79 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043976 histone H3K79 acetylation|histone H3 acetylation at K79 The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 79 of the histone. CHEBI:77297 1-(Z)-alk-1-enyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77297 CHEBI:28339 lactose 6'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28339 GO:0043982 histone H4-K8 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043982 histone H4 acetylation at K8 The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 8 of the histone. GO:0043981 histone H4-K5 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043981 histone H4 acetylation at K5 The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 5 of the histone. GO:0043984 histone H4-K16 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043984 histone H4 acetylation at K16 The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 16 of the histone. GO:0043983 histone H4-K12 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043983 histone H4 acetylation at K12 The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 12 of the histone. GO:0043980 histone H2B-K12 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043980 histone H2B acetylation at K12 The modification of histone H2B by the addition of an acetyl group to a lysine residue at position 12 of the histone. CHEBI:28331 erythromycin D biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28331 CHEBI:28330 4-hydroxy-L-threonine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28330 GO:0043989 histone H4-S1 phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043989 histone H4 phosphorylation at S1|histone H4S1 phosphorylation The modification of histone H4 by the addition of an phosphate group to a serine residue at position 1 of the histone. CHEBI:233 (4S,7R)-4-isopropenyl-7-methyloxepan-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_233 CHEBI:232 (+)-cis-carveol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_232 GO:0043986 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043986 GO:0043985 histone H4-R3 methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043985 histone H4 methylation at R3|histone H4R3me|histone H4 R3 methylation The modification of histone H4 by addition of a methyl group to arginine at position 3 of the histone. GO:0043988 histone H3-S28 phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043988 histone H3S28 phosphorylation|histone H3 phosphorylation at S28 The modification of histone H3 by the addition of an phosphate group to a serine residue at position 28 of the histone. GO:0043987 histone H3-S10 phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043987 histone H3S10 phosphorylation|histone H3 phosphorylation at S10 The modification of histone H3 by the addition of an phosphate group to a serine residue at position 10 of the histone. CHEBI:28307 precorrin-3A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28307 CHEBI:28304 heparin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28304 CHEBI:28303 2-chlorobenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28303 GO:0043993 histone acetyltransferase activity (H3-K18 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043993 histone lysine N-acetyltransferase activity (H3-K18 specific) Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 18) = CoA + histone H3 N6-acetyl-L-lysine (position 18). CHEBI:28300 glutamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28300 GO:0043992 histone acetyltransferase activity (H3-K9 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043992 histone lysine N-acetyltransferase activity (H3-K9 specific) Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 9) = CoA + histone H3 N6-acetyl-L-lysine (position 9). GO:0043995 histone acetyltransferase activity (H4-K5 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043995 histone lysine N-acetyltransferase activity (H4-K5 specific) Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 5) = CoA + histone H4 N6-acetyl-L-lysine (position 5). CHEBI:28302 glucuronoarabinoxylan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28302 GO:0043994 histone acetyltransferase activity (H3-K23 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043994 histone lysine N-acetyltransferase activity (H3-K23 specific) Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 23) = CoA + histone H3 N6-acetyl-L-lysine (position 23). GO:0043991 histone H2B-S14 phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043991 histone H2BS14 phosphorylation|histone H2B phosphorylation at S14 The modification of histone H2B by the addition of an phosphate group to a serine residue at position 14 of the histone. GO:0043990 histone H2A-S1 phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043990 histone H2A phosphorylation at S1|histone H2AS1 phosphorylation The modification of histone H2A by the addition of an phosphate group to a serine residue at position 1 of the histone. GO:0043997 histone acetyltransferase activity (H4-K12 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043997 histone lysine N-acetyltransferase activity (H4-K12 specific) Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 12) = CoA + histone H4 N6-acetyl-L-lysine (position 12). GO:0043996 histone acetyltransferase activity (H4-K8 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043996 histone lysine N-acetyltransferase activity (H4-K8 specific) Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 8) = CoA + histone H4 N6-acetyl-L-lysine (position 8). GO:0043999 histone acetyltransferase activity (H2A-K5 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043999 histone lysine N-acetyltransferase activity (H2A-K5 specific) Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine (position 5) = CoA + histone H2A N6-acetyl-L-lysine (position 5). CHEBI:412516 5-hydroxymethylfurfural biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_412516 GO:0043998 H2A histone acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043998 H2A histone lysine N-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine = CoA + histone H2A N6-acetyl-L-lysine. CHEBI:28319 L-fucopyranose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28319 CHEBI:28318 3,6-dichlorocatechol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28318 PO:0025197 stele biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025197 estela (Spanish, exact)|中心柱, central cylinder (Japanese, exact) A cardinal organ part (PO:0025001) that is the central column of a plant axis that consists of the primary vascular tissue and associated ground tissue. PO:0025195 pollen tube cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025195 花粉管細胞 (Japanese, exact)|célula del tubo polínico (Spanish, exact) A native plant cell (PO:0025606) that develops from a microgametophyte vegetative cell (PO:0020099) and forms a tubular extension of the pollen (PO:0025281). CHEBI:28317 3-aminobutyryl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28317 CHEBI:28311 indol-3-ylacetaldehyde oxime biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28311 CHEBI:28310 1D-3-O-methyl-myo-inositol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28310 UBERON:0006135 myelinated nerve fiber biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006135 Axons of neurons encased in a lipoproteinaceous material called myelin. (MeSH) UBERON:0006134 nerve fiber biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006134 nerve fibre|nerve fibers|neurofibra|neurofibra|neurofibrum A threadlike extension of a nerve cell and consists of an axon and myelin sheath (if it is myelinated) in the nervous system. There are nerve fibers in the central nervous system and peripheral nervous system. A nerve fiber may be myelinated and/or unmyelinated. In the central nervous system (CNS), myelin by oligodendroglia cells is formed. Schwann cells form myelin in the peripheral nervous system (PNS). Schwann cells also make a thin covering in an axon without myelin (in the PNS). A peripheral nerve fiber contains an axon, myelin sheath, schwann cells and its endoneurium. There are no endoneurium and schwann cells in the central nervous system. UBERON:0006133 funiculus of neuraxis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006133 The cerebrospinal nerves consist of numerous nerve fibers collected together and enclosed in membranous sheaths. A small bundle of fibers, enclosed in a tubular sheath, is called a funiculus; if the nerve is of small size, it may consist only of a single funiculus; but if large, the funiculi are collected together into larger bundles or fasciculi, which are bound together in a common membranous investment. Examples include: Anterior funiculus of the spinal cord Lateral funiculus of the spinal cord Posterior funiculus of the spinal cord Funiculus solitarius of the medulla Funiculus separans UBERON:0006136 unmyelinated nerve fiber biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006136 non-myelinated nerve fiber UBERON:0006192 mesonephric proximal tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006192 The mesonephric proximal tubule extends from the capsule to the distal tubule UBERON:0006190 mesonephric distal tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006190 The mesonephric distal tubule is a mesonephric nephron tubule that begins at the macula densa and extends to the mesonephric connecting tubule CHEBI:18946 delta-lactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18946 UBERON:0006196 mesonephric sinus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006196 A renal sinus that is part of a mesonephros. UBERON:0006195 renal sinus of left kidney biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006195 left renal sinus A renal sinus that is part of a left kidney. UBERON:0006194 renal sinus of right kidney biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006194 right renal sinus A renal sinus that is part of a right kidney. UBERON:0006182 mesonephric glomerular mesangium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006182 The mesonephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the mesonephros, which helps to support the capillary loops in a renal glomerulus UBERON:0006189 mesonephric connecting tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006189 The mesonephric connecting tubule is a tubular segment of the mesonephric nephron; it connects the distal tubule to the collecting duct in the mesonephros UBERON:0006183 mesonephric glomerular capillary biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006183 . UBERON:0006171 renal sinus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006171 A hollowed out area on the medial margin of the kidney. The renal sinus opens at the renal hilum; it contains the renal aa. and vv., major calyces and renal pelvis, perirenal fat UBERON:0006170 mesonephric capsule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006170 The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. UBERON:0006175 pronephric distal tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006175 UBERON:0006174 pronephric sinus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006174 The pronephric sinus is an ill-defined capillary network that lies between the pronephric tubules UBERON:0006173 pronephric proximal tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006173 pronephros proximal tubule UBERON:0006172 rectal diverticulum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006172 rectal diverticula The rectal diverticulum is an outgrowth of the cloaca and links the pronephric kidney to the exterior CHEBI:77219 (9Z,12Z)-hexadecadienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77219 CHEBI:77218 (23Z,26Z,29Z,32Z,35Z)-octatriacontapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77218 CHEBI:77217 (18Z,21Z,24Z,27Z,30Z,33Z)-hexatriacontahexaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77217 PO:0025262 plant ovary septum biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025262 carpel synonym (related)|ovary dissepiment (broad)|子房隔壁 (Japanese, exact)|septo del ovario (Spanish, exact)|ovary septa (exact, plural) A septum (PO:0000030) that divides a multilocular plant ovary (PO:0009072). GO:0018928 methyl ethyl ketone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018928 UM-BBD_pathwayID:mek methyl ethyl ketone metabolism|MEK metabolic process|2-butanone metabolic process|MEK metabolism|2-butanone metabolism The chemical reactions and pathways involving methyl ethyl ketone, a clear, colorless liquid with a fragrant, mint-like odor. It is used as a solvent and in making plastics, textiles and paints. GO:0018927 obsolete methionine and threonine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018927 methionine and threonine metabolic process OBSOLETE. (Was not defined before being made obsolete). GO:0018929 methyl fluoride metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018929 UM-BBD_pathwayID:mf methyl fluoride metabolism The chemical reactions and pathways involving methyl fluoride, fluorine-substituted methane, a gaseous halogenated hydrocarbon that has been investigated as an inhibitor of methanotrophy and nitrification in soils. CHEBI:28286 cyclohexane-1,4-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28286 GO:0018924 mandelate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018924 UM-BBD_pathwayID:mca mandelate metabolism|mandelic acid metabolism|mandelic acid metabolic process The chemical reactions and pathways involving mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic. GO:0018923 limonene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018923 UM-BBD_pathwayID:lim limonene metabolism The chemical reactions and pathways involving limonene (4-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene. CHEBI:28291 3-hydroxyisovaleryl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28291 GO:0018926 methanesulfonic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018926 UM-BBD_pathwayID:msa methanesulphonic acid metabolic process|methanesulfonic acid metabolism|methanesulphonic acid metabolism The chemical reactions and pathways involving methanesulfonic acid, a strong acid produced by the oxidation of dimethyl sulfide. CHEBI:28294 dTDP-4-acetamido-4,6-dideoxy-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28294 GO:0018925 m-cresol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018925 MetaCyc:M-CRESOL-DEGRADATION-PWY|UM-BBD_pathwayID:mcr m-cresol metabolism|3-hydroxytoluene metabolism|meta-cresol metabolism|meta-cresol metabolic process|3-hydroxytoluene metabolic process The chemical reactions and pathways involving m-cresol (3-hydroxytoluene), the meta-isoform of cresol. Used to produce agricultural chemicals, and in specialty resins, pharmaceuticals and pressure-sensitive dyes. CHEBI:28293 (S)-1-aminopropan-2-yl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28293 GO:0018920 glyphosate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018920 UM-BBD_pathwayID:gly Roundup metabolic process|glyphosate metabolism|Roundup metabolism The chemical reactions and pathways involving glyphosate, a broad-spectrum herbicide also known by the trade name Roundup. It is a member of a broad class of compounds known as phosphonic acids, which contain a direct carbon-to-phosphorus (C-P) bond. GO:0018922 iprodione metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018922 UM-BBD_pathwayID:ipd iprodione metabolism The chemical reactions and pathways involving prodione, a colorless, odorless crystal. It is used as a dicarboximide contact fungicide to control a wide variety of crop diseases by inhibiting the germination of spores and the growth of the fungal mat (mycelium). GO:0018921 3-hydroxybenzyl alcohol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018921 UM-BBD_pathwayID:mcr 3-hydroxybenzyl alcohol metabolism The chemical reactions and pathways involving 3-hydroxybenzyl alcohol, an aromatic compound which is an intermediate in several metabolic pathways, including the biosynthesis of patulin, a toxin and antiviral agent produced by some moulds such as Penicillium patulinum. CHEBI:77212 (17Z,20Z,23Z,26Z,29Z)-dotriacontapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77212 CHEBI:77211 (12Z,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77211 UBERON:0006208 auditory hillocks biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006208 auditory hillock of Hiss|auditory tubercles|hillock of Hiss|auricular hillock A collection of protruberances derived from pharyngeal arches 1 and 2 that develop into the folds of the pinna and gradually shift upwards and backwards to their final position on the head. UBERON:0006207 aortico-pulmonary spiral septum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006207 septum aorticopulmonale|aortic septum|spiral septum|aortico-pulmonary septum|aorticopulmonary septum The spiral septum that separates the truncus arteriosus into a ventral pulmonary trunk and the dorsal aorta[MP]. The aorticopulmonary septum is developmentally formed from neural crest, specifically the cardiac neural crest, and actively separates the aorta and pulmonary arteries and fuses with the interventricular septum within the heart during development. The actual mechanism of septation of the outflow tract is poorly understood, but is recognized as a dynamic process with contributions from contractile, hemodynamic, and extracellular matrix interactions. UBERON:0006206 iridocorneal angle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006206 anterior chamber angle Acute angle occurring between the iris and the cornea at the periphery of the anterior chamber of the eye[MP]. CHEBI:77216 (21Z,24Z,27Z,30Z,33Z)-hexatriacontapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77216 CHEBI:77215 (16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77215 CHEBI:77214 (19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77214 CHEBI:53242 vinyl polymer macromolecule biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_53242 CHEBI:77213 (14Z,17Z,20Z,23Z,26Z,29Z)-dotriacontahexaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77213 CHEBI:77229 (11Z,14Z,17Z,20Z)-hexacosatetraenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77229 CHEBI:77228 (6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77228 GO:0018939 n-octane metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018939 UM-BBD_pathwayID:oct n-octane metabolism The chemical reactions and pathways involving n-octane, the 8 carbon straight chain alkane used in organic syntheses, calibrations, and azeotropic distillations. It is a common component of gasoline and other petroleum products and the engine fuel antiknocking properties of an isomer of n-octane are used as a comparative standard in the Octane Rating System. CHEBI:28296 L-alpha-glutamyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28296 GO:0018938 2-nitropropane metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018938 MetaCyc:PWY-723|UM-BBD_pathwayID:npp 2-nitropropane metabolism The chemical reactions and pathways involving 2-nitropropane, a clear, colorless liquid with a mild, fruity odor. 2-nitropropane is used principally as a solvent and chemical intermediate. As a solvent, it is used in inks, paints, adhesives, varnishes, polymers, and synthetic materials. It is a feedstock for the manufacture of 2-nitro-2-methyl-1-propanol and 2-amino-2-methyl-1-propanol. CHEBI:28295 2-deoxystreptamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28295 CHEBI:28297 hydantoin-5-propionic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28297 GO:0043902 positive regulation of multi-organism process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043902 Any process that activates or increases the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species. GO:0018935 aerobic nitrilotriacetate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018935 aerobic nitrilotriacetate metabolism The chemical reactions and pathways involving nitrilotriacetate, the aminotricarboxylic acid N(CH2COO-)3, that occur in the presence of oxygen. GO:0018934 nitrilotriacetate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018934 UM-BBD_pathwayID:nta nitrilotriacetate metabolism The chemical reactions and pathways involving nitrilotriacetate, an aminotricarboxylic acid that binds bivalent metal ions in a ratio of 1:1. As an important industrial chelating agent, NTA has been widely used for various radionuclide processing and decontamination procedures, such as textile, paper and pulp processing and water treatment. GO:0043901 negative regulation of multi-organism process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043901 Any process that stops, prevents, or reduces the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species. GO:0043904 isochorismate pyruvate lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043904 MetaCyc:RXN-1981|RHEA:27874|EC:4.2.99.21 isochorismate-pyruvate lyase activity|IPL Catalysis of the reaction: isochorismate = salicylate + pyruvate. GO:0018937 nitroglycerin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018937 UM-BBD_pathwayID:ng|MetaCyc:P201-PWY NG metabolic process|nitroglycerin metabolism|NG metabolism The chemical reactions and pathways involving nitroglycerin, a well-known nitrate ester and an important component of dynamite and other propellants. Toxic to algae, invertebrate, and vertebrates. GO:0043903 regulation of biological process involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043903 regulation of symbiosis, encompassing mutualism through parasitism|regulation of interspecies interactions between organisms|regulation of symbiotic process Any process that modulates the frequency, rate or extent of symbiosis, an interaction between two organisms living together in more or less intimate association. GO:0018936 anaerobic nitrilotriacetate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018936 anaerobic nitrilotriacetate metabolism The chemical reactions and pathways involving nitrilotriacetate, the aminotricarboxylic acid N(CH2COO-)3, that occur in the absence of oxygen. GO:0018931 naphthalene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018931 UM-BBD_pathwayID:naph naphthalene metabolism The chemical reactions and pathways involving naphthalene, a fused ring bicyclic aromatic hydrocarbon commonly found in crude oil and oil products. Naphthalene is familiar as the compound that gives mothballs their odor; it is used in the manufacture of plastics, dyes, solvents, and other chemicals, as well as being used as an antiseptic and insecticide. GO:0018930 3-methylquinoline metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018930 UM-BBD_pathwayID:mqn 3-methylquinoline metabolism The chemical reactions and pathways involving 3-methylquinoline, C10H9N, an aromatic compound composed of a benzene ring and a heterocyclic N-containing ring. GO:0018933 nicotine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018933 nicotine metabolism The chemical reactions and pathways involving nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine. GO:0043900 regulation of multi-organism process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043900 Any process that modulates the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species. GO:0018932 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018932 CHEBI:77223 (11Z,14Z,17Z)-icosatrienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77223 GO:0043909 N-acetylcitrulline deacetylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043909 RHEA:61092 acetylcitrulline deacetylase activity|N-acetyl-L-citrulline deacetylase activity Catalysis of the reaction: N-acetyl-L-citrulline + H2O = citrulline + acetate. CHEBI:77222 (6Z,9Z,12Z,15Z)-octadecatetraenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77222 CHEBI:77221 (17Z)-hexacosenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77221 CHEBI:77220 (11Z,14Z)-icosadienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77220 GO:0043906 Ala-tRNA(Pro) hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043906 EC:3.1.1.- Ala-tRNAPro hydrolase activity Catalysis of the hydrolysis of misacylated Ala-tRNA(Pro). CHEBI:77227 (9Z,12Z,15Z,18Z)-tetracosatetraenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77227 GO:0043905 Ser-tRNA(Thr) hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043905 EC:3.1.1.- Ser-tRNAThr hydrolase activity Catalysis of the hydrolysis of misacylated Ser-tRNA(Thr). CHEBI:77226 (4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77226 GO:0043908 Ser(Gly)-tRNA(Ala) hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043908 EC:3.1.1.- Ser(Gly)-tRNAAla hydrolase activity Catalysis of the hydrolysis of misacylated Ser-tRNA(Ala) and Gly-tRNA(Ala). CHEBI:77225 all-cis-docosa-7,10,13,16-tetraenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77225 CHEBI:77224 (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77224 GO:0043907 Cys-tRNA(Pro) hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043907 EC:3.1.1.- Cys-tRNAPro hydrolase activity|Cys-tRNA(Pro) deacetylase activity Catalysis of the hydrolysis of misacylated Cys-tRNA(Pro). CHEBI:77239 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77239 NCBITaxon:6656 Arthropoda organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_6656 arthropods|arthropods CHEBI:53226 polyethylene macromolecule biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53226 CHEBI:28266 fluorene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28266 GO:0018909 dodecyl sulfate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018909 UM-BBD_pathwayID:dds dodecyl sulfate metabolism|dodecyl sulphate metabolic process|dodecyl sulphate metabolism The chemical reactions and pathways involving dodecyl sulfate, commonly found as sodium dodecyl sulfate (SDS), a component of a variety of synthetic surfactants. GO:0018906 methyl tert-butyl ether metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018906 UM-BBD_pathwayID:mtb methyl tert-butyl ether metabolism The chemical reactions and pathways involving methyl tert-butyl ether, 2-methoxy-2-methylpropane. Methyl tert-butyl ether is a synthetic chemical which is mixed with gasoline for use in reformulated gasoline. It was first introduced as an additive for unleaded gasoline in the 1980s. It is also used as a laboratory reagent and a pharmaceutical agent. CHEBI:28262 dimethyl sulfoxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28262 GO:0018905 dimethyl ether metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018905 UM-BBD_pathwayID:dme methyl ether metabolic process|methyl ether metabolism|dimethyl ether metabolism The chemical reactions and pathways involving dimethyl ether, CH3-O-CH3, the simplest ether. Dimethyl ether, also known wood ether and methyl ether, is a colorless gas that has been used in refrigeration applications. GO:0018908 organosulfide cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018908 UM-BBD_pathwayID:sulf organosulphide cycle A cyclic series of interconversions involving dimethyl sulfide, methanethiol and hydrogen sulfide. Dimethylsulfoxide can also be converted to dimethyl sulfide, which enters the cycle. CHEBI:28265 coenzyme F430 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28265 GO:0018907 dimethyl sulfoxide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018907 UM-BBD_pathwayID:sulf dimethyl sulphoxide metabolism|DMSO metabolic process|DMSO metabolism|dimethyl sulfoxide metabolism|dimethyl sulphoxide metabolic process The chemical reactions and pathways involving dimethyl sulfoxide, DMSO (C2H6OS), an alkyl sulfoxide that is practically odorless in its purified form. As a highly polar organic liquid, it is a powerful solvent. Its biological activities include the ability to penetrate plant and animal tissues and to preserve living cells during freezing. CHEBI:28264 3-oxooctanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28264 GO:0043913 obsolete chromosome segregation-directing complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043913 MreBCD complex|chromosome segregation directing complex|longitudinal peptidoglycan synthesis-directing complex OBSOLETE. A trimeric protein complex which in E. coli is composed of the subunits MreB, MreC and MreD. The complex directs longitudinal cell wall synthesis, maintaining cell morphology. GO:0018902 1,3-dichloro-2-propanol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018902 UM-BBD_pathwayID:dcp DCP metabolic process|1,3-dichloro-2-propanol metabolism|DCP metabolism The chemical reactions and pathways involving 1,3-dichloro-2-propanol (DCP), a halohydrin suspected of being carcinogenic, mutagenic and genotoxic. DCP is used as a general solvent, as an intermediate in organic synthesis and in paints, varnishes, lacquers, water colors, binders and photographic lacquers. GO:0043912 D-lysine oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043912 EC:1.4.3.- Catalysis of the reaction: D-lysine + O2 + H2O = 6-amino-2-oxohexanoate + NH3 + hydrogen peroxide. GO:0018901 2,4-dichlorophenoxyacetic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018901 UM-BBD_pathwayID:2,4-d 2,4-D metabolic process|2,4-dichlorophenoxyacetic acid metabolism|2,4-D metabolism The chemical reactions and pathways involving 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds. GO:0043915 L-seryl-tRNA(Sec) kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043915 EC:2.7.1.164|MetaCyc:RXN-10038|RHEA:25037 O-phosphoseryl-tRNA(Sec) kinase activity Catalysis of the reaction: ATP + L-seryl-tRNA(Sec) = ADP + O-phospho-L-seryl-tRNA(Sec). GO:0018904 ether metabolic process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0018904 organic ether metabolic process|ether metabolism|organic ether metabolism The chemical reactions and pathways involving organic ethers, any anhydride of the general formula R1-O-R2, formed between two identical or nonidentical organic hydroxy compounds. CHEBI:28272 beta-L-arabinofuranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28272 GO:0043914 NADPH:sulfur oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043914 EC:1.8.1.18 coenzyme A-dependent NAD(P)H sulfur oxidoreductase activity|NAD(P)H sulfur oxidoreductase activity|NAD(P)H:sulfur oxidoreductase activity|NAD(P)H elemental sulfur oxidoreductase activity|CoA-dependent NAD(P)H sulfur oxidoreductase activity|NAD(P)H sulphur oxidoreductase activity|NSR|NADPH:sulphur oxidoreductase activity Catalysis of the reaction: NADPH + H+ + sulfur = hydrogen sulfide + NADP+. GO:0018903 1,3-dichloropropene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018903 UM-BBD_pathwayID:cpr 1,3-dichloropropene metabolism|gamma-chloroallylchloride metabolic process|1,3-dichloropropylene metabolic process|1,3-dichloropropylene metabolism|gamma-chloroallylchloride metabolism The chemical reactions and pathways involving members of the 1,3-dichloropropene family, which includes cis- and trans-1,3-dichloropropene. The 1,3-dichloropropenes are chlorinated hydrocarbons and the major active ingredients of commercial products for control of plant-parasitic nematodes. GO:0043911 D-lysine transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043911 D-lysine aminotransferase activity Catalysis of the reaction: D-lysine + 2-oxoglutarate = L-glutamate + 6-amino-2-oxohexanoate. GO:0018900 dichloromethane metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018900 UM-BBD_pathwayID:dcm dichloromethane metabolism The chemical reactions and pathways involving dichloromethane, a dichlorinated derivative of methane. It is a colorless organic liquid with a sweet, chloroform-like odor, often used as a paint remover. GO:0043910 ATP:coenzyme F420 adenylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043910 MetaCyc:RXN-9385 ATP:coenzyme F420 adenyltransferase activity|coenzyme F390-A synthetase activity Catalysis of the reaction: ATP + factor gamma-F420-2 + H+ = coenzyme F390-A + diphosphate. CHEBI:77234 (19Z,22Z,25Z,28Z)-tetratriacontatetraenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77234 CHEBI:77233 (17Z,20Z,23Z,26Z)-dotriacontatetraenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77233 CHEBI:53225 poly(alkylene) macromolecule biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53225 CHEBI:77232 (15Z,18Z,21Z,24Z)-triacontatetraenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77232 NCBITaxon:89593 Craniata organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_89593 Craniata CHEBI:53224 poly(amide) macromolecule biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53224 CHEBI:77231 (13Z,16Z,19Z,22Z)-octacosatetraenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77231 GO:0043917 ribose 1,5-bisphosphate isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043917 MetaCyc:RXN-8801|EC:5.3.1.29|RHEA:32243 ribose-1,5-bisphosphate isomerase activity Catalysis of the reaction: D-ribose 1,5-bisphosphate = D-ribulose 1,5-bisphosphate. GO:0043916 DNA-7-methylguanine glycosylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043916 MetaCyc:3.2.2.21-RXN|EC:3.2.2.21 Catalysis of the reaction: DNA containing 7-methylguanine + H2O = DNA with abasic site + 7-methylguanine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 7-methylguanine and the deoxyribose sugar to remove the 7-methylguanine, leaving an abasic site. CHEBI:77237 O-hexadecanedioyl-L-carnitine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77237 GO:0043919 agmatine aminopropyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043919 EC:2.5.1.104 agmatine aminopropyl transferase activity Catalysis of the reaction: agmatine + S-adenosylmethioninamine = N1-aminopropylagmatine + 5'-methylthioadenosine. CHEBI:77236 (23Z,26Z,29Z,32Z)-octatriacontatetraenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77236 GO:0043918 cadaverine aminopropyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043918 EC:2.5.1.104 cadaverine aminopropyl transferase activity Catalysis of the reaction: S-adenosylmethioninamine + cadaverine = 5'-methylthioadenosine + N-(3-aminopropyl)cadaverine. CHEBI:77235 (21Z,24Z,27Z,30Z)-hexatriacontatetraenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77235 PO:0025233 portion of embryo plant tissue biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025233 portion of embryo tissue (broad)|tejido embriónico vegetal (Spanish, exact)|植物胚性組織 の一部 (Japanese, exact)|portion of embryonic plant tissue (exact) A portion of plant tissue (PO:0009007) that is part of a plant embryo (PO:0009009). CHEBI:43896 alpha-D-mannose 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_43896 CHEBI:28279 6-methylthiopurine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28279 GO:0018917 fluorene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018917 UM-BBD_pathwayID:flu fluorene metabolism The chemical reactions and pathways involving fluorene, a tricyclic polycyclic aromatic hydrocarbon containing a five-membered ring. It is a major component of fossil fuels and their derivatives and is also a by-product of coal-conversion and energy-related industries. It is commonly found in vehicle exhaust emissions, crude oils, motor oils, coal and oil combustion products, waste incineration, and industrial effluents. GO:0018916 nitrobenzene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018916 UM-BBD_pathwayID:nb nitrobenzene metabolism The chemical reactions and pathways involving nitrobenzene (nitrobenzol), a derivative of benzene with an NO2 group attached to the ring. It is a yellow aromatic liquid used in perfumery and manufactured in large quantities in the preparation of aniline. CHEBI:28273 aldehydo-N-acetyl-D-mannosamine 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28273 GO:0018919 gamma-1,2,3,4,5,6-hexachlorocyclohexane metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018919 UM-BBD_pathwayID:ghch|MetaCyc:GAMMAHEXCHLORDEG-PWY gamma-1,2,3,4,5,6-hexachlorocyclohexane metabolism The chemical reactions and pathways involving gamma-1,2,3,4,5,6-hexachlorocyclohexane (also known as Lindane), the most common form of hexachlorohexane, a halogenated organic insecticide that has been used worldwide for agriculture and public health. CHEBI:28276 (S)-3-hydroxyhexanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28276 GO:0018918 gallate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018918 UM-BBD_pathwayID:gal gallic acid metabolism|gallate metabolism|gallic acid metabolic process The chemical reactions and pathways involving gallate, the anion of gallic acid (3,4,5-trihydroxybenzoic acid). The esters and polyesters are widely distributed in angiosperms. GO:0043924 suramin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043924 Germanin binding Interacting selectively and non-covalently with suramin, a naphthalenesulfonic acid compound which is used in the treatment of diseases caused by trypanosomes and worms. GO:0018913 anaerobic ethylbenzene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018913 UM-BBD_pathwayID:ethb anaerobic ethylbenzene metabolism The chemical reactions and pathways involving ethylbenzene (phenylethane), a benzene derivative with an ethyl group attached to the ring, that occur in the absence of oxygen. GO:0043923 positive regulation by host of viral transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043923 positive regulation of viral transcription by host Any process in which a host organism activates or increases the frequency, rate or extent of viral transcription, the synthesis of either RNA on a template of DNA or DNA on a template of RNA. GO:0018912 1,4-dichlorobenzene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018912 UM-BBD_pathwayID:dcz 1,4-dichlorobenzene metabolism The chemical reactions and pathways involving 1,4-dichlorobenzene (p-dichlorobenzene or paramoth), a derivative of benzene with two chlorine atoms attached at opposite positions on the ring. It forms white crystals at room temperature and is used as an insecticidal fumigant, particularly in mothballs. CHEBI:28283 capsidiol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28283 GO:0018915 ethylbenzene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018915 UM-BBD_pathwayID:ethb2 ethylbenzene metabolism The chemical reactions and pathways involving ethylbenzene (phenylethane), a benzene derivative with an ethyl group attached to the ring. It is a colorless liquid with a pungent odor used as a solvent and as a component of automotive and aviation fuels. GO:0043926 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043926 GO:0018914 chlorobenzene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018914 UM-BBD_pathwayID:cb chlorobenzene metabolism The chemical reactions and pathways involving chlorobenzene, a derivative of benzene with a chlorine atoms attached to the ring. It is a colorless liquid that is manufactured for use as a solvent. It quickly evaporates in the air and is degraded by hydroxyl radicals that are produced photochemically. The gas acts as a source of ClOx, which helps in the breakdown of stratospheric ozone. CHEBI:28282 N-benzyloxycarbonyl-L-leucine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28282 GO:0043925 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043925 CHEBI:77241 1-icosanoyl-2-arachidonoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77241 GO:0043920 aminopropylagmatine ureohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043920 RHEA:35828 Catalysis of the reaction: N1-aminopropylagmatine + H2O = spermidine + urea. CHEBI:77240 alpha-L-Fucp-(1->3)-[beta-D-Galp-(1->4)]-beta-D-GlcpNAc-(1->3)-beta-D-Galp-(1->4)-beta-D-Glcp-(1<->1')-Cer biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77240 GO:0043922 negative regulation by host of viral transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043922 negative regulation of viral transcription by host Any process in which a host organism stops, prevents, or reduces the frequency, rate or extent of viral transcription. GO:0018911 1,2,4-trichlorobenzene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018911 UM-BBD_pathwayID:tbz 1,2,4-trichlorobenzene metabolism The chemical reactions and pathways involving 1,2,4-trichlorobenzene, a derivative of benzene with chlorine atoms attached to positions 1, 2 and 4 of the ring. It is a colorless liquid used as a solvent in chemical manufacturing, in dyes and intermediates, dielectric fluid, synthetic transformer oils, lubricants, heat-transfer medium and insecticides. GO:0018910 benzene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018910 benzene metabolism The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation. GO:0043921 modulation by host of viral transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043921 regulation of viral transcription by host|regulation by host of viral transcription Any process in which a host organism modulates the frequency, rate or extent of viral transcription. PO:0025228 valve biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025228 valva (Spanish, exact)|弁 (Japanese, exact) A cardinal organ part that is a part of a plant structure that splits apart when the structure dehisces. GO:0043928 exonucleolytic catabolism of deadenylated mRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043928 The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 3'-poly(A) tail. GO:0043927 exonucleolytic nuclear-transcribed mRNA catabolic process involved in endonucleolytic cleavage-dependent decay biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043927 The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 5'-cap. CHEBI:77248 1-stearoyl-2-linoleoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77248 CHEBI:53210 O-propanoyl-L-carnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_53210 GO:0043929 primary ovarian follicle growth involved in double layer follicle stage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043929 primary ovarian follicle growth during double layer follicle stage Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle), as part of the double layer follicle stage of oogenesis. PO:0025223 vegetative shoot apex biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025223 ápice vegetativo del epiblasto (epiblastema) (Spanish, exact)|栄養シュート頂、栄養枝頂 (Japanese, exact) A shoot apex PO:0000037) that has as part a vegetative shoot apical meristem (PO:0008016). CHEBI:28245 (S)-2-amino-6-oxopimelic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28245 CHEBI:28247 11beta-hydroxyprogesterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28247 UBERON:0006245 humerus cartilage element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006245 humeral cartilage condensation A humerus endochondral element that is composed primarily of cartilage tissue. GO:0043935 sexual sporulation resulting in formation of a cellular spore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043935 The formation of spores derived from the products of meiosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction. GO:0043934 sporulation biolink:BiologicalProcess go-plus goslim_metagenomics|goslim_yeast http://purl.obolibrary.org/obo/GO_0043934 Wikipedia:Spore The process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. A spore is a structure that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction. CHEBI:28250 6-O-acetyl-beta-D-galactoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28250 PR:000005663 ciliary neurotrophic factor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000005663 CNTF A protein that is a translation product of the human CNTF gene or a 1:1 ortholog thereof. GO:0043937 regulation of sporulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043937 Any process that modulates the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. GO:0043936 asexual sporulation resulting in formation of a cellular spore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043936 asexual sporulation resulting in the formation of a viable spore|asexual reproduction resulting in the formation of a cellular spore The formation of a cellular spore derived from the products of mitosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction. UBERON:0006242 gall bladder primordium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006242 A sac-like cavity ventral to the liver, lying in the sub-mesodermal space and closed by a thin sheet of ectodermal cells, from which the future gall bladder develops. GO:0043931 ossification involved in bone maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043931 ossification involved in skeletal development|ossification involved in bone modeling The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in the progression of the skeleton from its formation to its mature state. UBERON:0006241 future spinal cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006241 presumptive spinal cord neural keel|presumptive spinal cord|presumptive spinal cord neural plate|presumptive spinal cord neural rod CHEBI:77252 1,2-diarachidonoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77252 UBERON:0006240 future forebrain biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006240 future prosencephalon|prosencephalon|presumptive prosencephalon|presumptive forebrain A presumptive structure that has the potential to develop into a forebrain. CHEBI:77251 (25S)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77251 GO:0043930 primary ovarian follicle growth involved in primary follicle stage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043930 primary ovarian follicle growth during primary follicle stage Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle) as part of the primary follicle stage of oogenesis. GO:0043933 protein-containing complex subunit organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043933 cellular macromolecular complex organization|cellular macromolecular complex subunit organization|protein complex subunit organisation|macromolecular complex subunit organisation|protein complex subunit organization|macromolecular complex organization|macromolecular complex subunit organization|cellular macromolecular complex subunit organisation Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex. CHEBI:77250 pristanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77250 GO:0043932 ossification involved in bone remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043932 ossification involved in bone remodelling The formation or growth of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in response to injury or other physical, physiological or environmental stress stimuli. CHEBI:77256 1,1'-dioleyl 2,2'-dilysocardiolipin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77256 CHEBI:77255 EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77255 CHEBI:77254 1,2-dilinoleoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77254 CHEBI:77253 tetraoleoyl cardiolipin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77253 GO:0043939 negative regulation of sporulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043939 Any process that stops, prevents, or reduces the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. GO:0043938 positive regulation of sporulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043938 Any process that activates, maintains or increases the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. CHEBI:77259 trioleoyl 2-monolysocardiolipin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77259 CHEBI:77258 1-stearoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77258 CHEBI:77257 (2S)-2-methylpentadecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77257 UBERON:0006246 humerus pre-cartilage condensation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006246 humeral pre-cartilage condensation A humerus endochondral element that is composed primarily of a pre-cartilage condensation. PO:0025297 seedling radicle biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025297 radícula de la plántula (Spanish, exact)|実生幼根 (Japanese, exact) A radicle (PO:0020031) that is part of a whole plant (PO:0000003) in the seedling development stage (PO:0007131). PO:0025296 plant embryo radicle biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025296 胚幼根 (Japanese, exact)|radícula del embrión (Spanish, exact)|embryonic radicle (exact) A radicle (PO:0020031) that is part of a plant embryo (PO:0009009). CHEBI:28259 (S)-3-hydroxyisobutyryl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28259 GO:0043940 regulation of sexual sporulation resulting in formation of a cellular spore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043940 Any process that modulates the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis. CHEBI:28258 vomifoliol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28258 CHEBI:28257 N-acetyl-alpha-D-galactosaminide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28257 GO:0043946 positive regulation of catalytic activity in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043946 up-regulation of enzyme activity in other organism during symbiotic interaction|activation of enzyme activity in other organism|up regulation of enzyme activity in other organism during symbiotic interaction|positive regulation of catalytic activity in other organism during symbiotic interaction|upregulation of enzyme activity in other organism during symbiotic interaction|activation of enzyme activity in other organism during symbiotic interaction Any process in which an organism activates, maintains or increases the frequency, rate or extent of enzyme activity in a second organism, where the two organisms are in a symbiotic interaction. UBERON:0006234 femur pre-cartilage condensation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006234 femoral pre-cartilage condensation A femur endochondral element that is composed primarily of a pre-cartilage condensation. GO:0043945 positive regulation of asexual sporulation resulting in formation of a cellular spore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043945 Any process that activates, maintains or increases the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis. UBERON:0006233 female genital tubercle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006233 genital tubercle of female A differentiated genital tubercle that is part of a female reproductive system. GO:0043948 induction by symbiont of host catalytic activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043948 upregulation by symbiont of host enzyme activity|up-regulation by symbiont of host enzyme activity|activation by symbiont of host enzyme activity|positive regulation by symbiont of host catalytic activity|positive regulation by symbiont of host enzyme activity|up regulation by symbiont of host enzyme activity|activation of host enzyme activity Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of host enzyme activity. The host is defined as the larger of the organisms involved in a symbiotic interaction. UBERON:0006232 facio-acoustic VII-VIII preganglion complex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006232 facio-acoustic preganglion complex CHEBI:28261 (+)-alpha-pinene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28261 GO:0043947 positive regulation by host of symbiont catalytic activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043947 up-regulation by host of symbiont enzyme activity|activation by host of symbiont enzyme activity|positive regulation by host of symbiont enzyme activity|up regulation by host of symbiont enzyme activity|activation of symbiont enzyme activity|upregulation by host of symbiont enzyme activity Any process in which an organism activates, maintains or increases the frequency, rate or extent of symbiont enzyme activity. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:28260 galactose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28260 GO:0043942 negative regulation of sexual sporulation resulting in formation of a cellular spore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043942 Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis. CHEBI:77263 6-deoxy-6-sulfo-D-fructofuranose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77263 UBERON:0006230 extrinsic ocular pre-muscle mass biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006230 GO:0043941 positive regulation of sexual sporulation resulting in formation of a cellular spore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043941 Any process that activates, maintains or increases the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis. GO:0043944 negative regulation of asexual sporulation resulting in formation of a cellular spore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043944 Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis. CHEBI:77261 6-deoxy-6-sulfo-D-fructofuranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77261 GO:0043943 regulation of asexual sporulation resulting in formation of a cellular spore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043943 Any process that modulates the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis. CHEBI:77267 3-sulfopropanediol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77267 CHEBI:77265 3-sulfolactaldehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77265 UBERON:0006239 future central tendon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006239 cranial derivative of septum transversum|cranial part of septum transversum A tendon that has the potential to develop into a central tendon. UBERON:0006238 future brain biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006238 encephalon|brain rudiment|embryonic brain|presumptive brain The embryonic precursor of the brain. GO:0043949 regulation of cAMP-mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043949 regulation of cAMP-mediated signalling Any process which modulates the frequency, rate or extent of cAMP-mediated signaling, a series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response. UBERON:0006236 tetrapod frontal bone primordium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006236 frontal bone primordium CHEBI:77269 dTDP-beta-L-evernitrose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77269 UBERON:0006235 foregut-midgut junction biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006235 An anatomical junctions that overlaps the foregut and midgut. CHEBI:77268 pristanate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77268 CHEBI:28229 N(omega)-methyl-L-arginine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28229 PO:0025281 pollen biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025281 pollen grain (exact)|polen (Spanish, exact)|花粉 (Japanese, exact) A microgametophyte (PO:0025280) that develops from a microspore (PO:0020048) is located in a pollen sac (PO:0025277). CHEBI:28228 S-acetylphosphopantotheine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28228 CHEBI:28223 adenosine 2'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28223 PO:0025280 microgametophyte biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025280 microgametofito (Spanish, exact)|小配偶体 (Japanese, exact)|male gametophyte (exact) A whole plant (PO:0000003) in the gametophyte development stage (PO:0028003) that produces plant sperm cells (PO:0000084). CHEBI:28222 1,2,4-trichlorobenzene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28222 CHEBI:28225 D-leucine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28225 GO:0043951 negative regulation of cAMP-mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043951 negative regulation of cAMP-mediated signalling Any process which stops, prevents, or reduces the frequency, rate or extent of cAMP-mediated signaling, a series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response. GO:0043950 positive regulation of cAMP-mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043950 positive regulation of cAMP-mediated signalling Any process which activates, maintains or increases the frequency, rate or extent of cAMP-mediated signaling, a series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response. CHEBI:28220 2,6-dihydroxypseudooxynicotine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28220 GO:0043957 acryloyl-CoA reductase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043957 KEGG_REACTION:R00919|MetaCyc:RXN-9087|EC:1.3.1.84|RHEA:26456 acryloyl-CoA reductase (NADPH) activity|AMP-dependent synthetase and ligase|AMP-dependent synthetase and ligase:enoyl-CoA hydratase/isomerase|acrylyl-CoA reductase (NADPH) activity|acetyl-coenzyme A synthetase/GroES-like domain|acetyl-coenzyme A synthetase|enoyl-CoA hydratase/isomerase Catalysis of the reaction: acryloyl-CoA + NADPH + H+ = propionyl-CoA + NADP+. UBERON:0006222 future diencephalon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006222 presumptive diencephalon The foremost region of the future forebrain that develops into the diencephalon. GO:0043956 3-hydroxypropionyl-CoA dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043956 RHEA:26518|MetaCyc:RXN-6383|EC:4.2.1.116 3-hydroxy propionyl-CoA dehydratase activity|AMP-dependent synthetase and ligase|AMP-dependent synthetase and ligase:Enoyl-CoA hydratase/isomerase|acetyl-coenzyme A synthetase/GroES-like domain|acetyl-coenzyme A synthetase|enoyl-CoA hydratase/isomerase Catalysis of the reaction: 3-hydroxypropionyl-CoA = acrylyl-CoA + H2O. GO:0043959 L-erythro-3-methylmalyl-CoA lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043959 EC:4.1.3.24 HpcH/HpaI aldolase Catalysis of the reaction: propionyl-CoA + glyoxylate = L-erythro-3-methylmalyl-CoA. GO:0043958 acryloyl-CoA reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043958 EC:1.3.99.3|MetaCyc:RXN-8568|RHEA:34471 acryloyl-coenzyme A reductase activity|propionyl-CoA dehydrogenase|acrylyl-CoA reductase (NADH) Catalysis of the reaction: acryloyl-CoA + NADH + H+ + a reduced electron-transfer flavoprotein = propionyl-CoA + NAD+ + an oxidized electron-transfer flavoprotein. CHEBI:77274 1-alkyl-3-acyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77274 GO:0043953 protein transport by the Tat complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043953 twin-arginine translocation pathway|protein secretion by the TAT complex|protein translocation by the TAT complex|protein translocation by the twin-arginine translocation complex The process in which folded proteins are transported across cytoplasmic membranes of bacteria and membranes of organelles derived from bacteria (chloroplasts and mitochondria) by the TAT complex. GO:0043952 protein transport by the Sec complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043952 protein secretion by the Sec complex|protein translocation by the Sec complex The process in which unfolded proteins are transported across the cytoplasmic membrane in Gram-positive and Gram-negative bacteria by the Sec complex, in a process involving proteolytic cleavage of an N-terminal signal peptide. CHEBI:77272 1,3-diacyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77272 GO:0043955 3-hydroxypropionyl-CoA synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043955 EC:6.2.1.36|RHEA:26534 3-hydroxy propionyl-CoA synthetase activity|acetyl-coenzyme A synthetase/GroES-like domain|AMP-dependent synthetase and ligase|AMP-dependent synthetase and ligase:Enoyl-CoA hydratase/isomerase|acetyl-coenzyme A synthetase|enoyl-CoA hydratase/isomerase Catalysis of the reaction: 3-hydroxypropionate + ATP + CoA = 3-hydroxypropionyl-CoA + AMP + diphosphate. GO:0043954 cellular component maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043954 cellular component maintenance at cellular level The organization process that preserves a cellular component in a stable functional or structural state. CHEBI:77271 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-1D-myo-inositol 4-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77271 CHEBI:77277 1-stearoyl-2-oleoyl-sn-glycero-3-phospho-1D-myo-inositol 4-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77277 CHEBI:77276 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-1D-myo-inositol 4,5-biphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77276 CHEBI:77275 (2R)-pristanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77275 UBERON:0006227 ethmoid bone primordium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006227 PO:0025279 megagametophyte biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025279 megagametofito (Spanish, exact)|female gametophyte (exact)|大配偶体 (Japanese, exact) A whole plant in the gametophyte development stage (PO:0028003) that produces only plant egg cells (PO:0020094). CHEBI:77279 1-stearoyl-2-oleoyl-sn-glycero-3-phospho-1D-myo-inositol 4,5-biphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77279 UBERON:0006224 elbow joint primordium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006224 PO:0025277 pollen sac biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025277 saco polínico (Spanish, exact)|Zea microsporangium (narrow)|花粉のう (Japanese, exact)|Poaceae microsporangium (narrow)|anther lobe (narrow) A microsporangium that is part of a sporophyll and where the pollen grains develop and are located after they develop. PO:0025275 procambium biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025275 procambio (Spanish, exact)|前形成層 (Japanese, exact) A portion of meristem tissue (PO:0009013) that undergoes differentiation to form the primary vascular tissue (PO:0025408). PO:0025272 plant ovary replum biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025272 placental septum (exact)|子房隔膜 (Japanese, exact)|false ovary septum (exact)|ovary dissepiment (broad)|replo (replum) del ovario (Spanish, exact) A portion of ovary placenta tissue (PO:0020001) which divides a plant ovary (PO:0009072) into two or more chambers, and develops from contact of the placental tissue from opposite sides of the plant ovary early in gynoecium development (GO:0048467). GO:0043960 L-erythro-3-methylmalyl-CoA dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043960 Catalysis of the reaction: L-erythro-3-methylmalyl-CoA = mesaconyl-CoA + H2O. CHEBI:28233 2,4,6-trihydroxybenzophenone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28233 GO:0043962 obsolete negative regulation by host of symbiont adenylate cyclase-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043962 OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0043961 succinyl-CoA:(R)-citramalate CoA-transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043961 RHEA:38279|EC:2.8.3.20|MetaCyc:RXN-8966 succinyl-CoA:R-citramalate CoA transferase|succinyl-CoA:(R)-citramalate CoA transferase activity|L-carnitine dehydratase/bile acid-inducible protein F Catalysis of the reaction: succinyl-CoA + (R)-citramalate = succinate + (R)-citramalyl-CoA. CHEBI:28230 hesperetin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28230 CHEBI:28232 D-ribose 5-triphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28232 GO:0043968 histone H2A acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043968 The modification of histone H2A by the addition of an acetyl group. CHEBI:77281 dTDP-N-hydroxy-beta-L-evernosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77281 GO:0043967 histone H4 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043967 The modification of histone H4 by the addition of an acetyl group. CHEBI:77280 dTDP-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitroso-beta-L-arabino-hexopyranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77280 CHEBI:211 (3S)-3-isopropenyl-6-oxoheptanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_211 UBERON:0006211 buccopharyngeal membrane biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006211 pharyngeal membrane|oral membrane|oral plate|oropharyngeal membrane The thin bilaminar membrane derived from the prechordal plate that is devoid of mesoderm and formed by the apposition of the stomodeal ectoderm with the foregut endoderm; after the embryonic head fold has evolved it lies at the caudal limit of the stomodeum, forming a septum between the primitive mouth and pharynx; the membrane eventually disappears, and thus a communication is established between the mouth and the future pharynx. UBERON:0006210 body-wall mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006210 GO:0043969 histone H2B acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043969 The modification of histone H2B by the addition of an acetyl group. CHEBI:43858 L-vinylglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_43858 GO:0043964 induction by symbiont of host adenylate cyclase-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043964 positive regulation by symbiont of host adenylate cyclase-mediated signal transduction Any process in which an organism activates, maintains or increases the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:77285 dTDP-beta-L-evernosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77285 GO:0043963 modulation by symbiont of host adenylate cyclase-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043963 Any process in which the symbiont modulates the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:77284 1-(Z)-alk-1-enyl-2-acyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77284 GO:0043966 histone H3 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043966 The modification of histone H3 by the addition of an acetyl group. CHEBI:77283 1-(Z)-alk-1-enyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77283 GO:0043965 suppression by symbiont of host adenylate cyclase-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043965 negative regulation by symbiont of host adenylate cyclase-mediated signal transduction Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. UBERON:0006219 deltoid pre-muscle mass biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006219 CHEBI:77288 1-(Z)-alk-1-enyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77288 CHEBI:77287 1-(Z)-alk-1-enyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77287 UBERON:0006218 common atrial chamber biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006218 CHEBI:77286 1-(Z)-alk-1-enyl-2-acyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77286 UBERON:0006217 cloacal membrane biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006217 membrana cloacalis|embryonic cloacal membrane The membrane that covers the embryonic cloaca, formed by the union of proctodeal (anal pit) ectoderm and cloacal endoderm, with no intervening mesoderm; the urorectal septum joins the cloacal membrane and divides it into an anal membrane and a urogenital membrane; the point where the urorectal septum intersects the cloacal membrane is the future site of the perineal body; proliferation of mesoderm and ectoderm around the cloacal membrane produces primordial tissues of the external genitalia in both sexes: the genital tubercle, genital folds, and genital swellings. PO:0025269 collective organ part structure biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025269 órgano colectivo de una parte de la estructura (Spanish, exact)|集合的器官の部分構造 (Japanese, exact) A collective plant structure (PO:0025497) composed of two or more cardinal organ parts (PO:0025001) that are part of adjacent plant organs (PO:0009008) and any associated portions of plant tissue (PO:0009007). UBERON:0006215 rhombic lip biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006215 cerebellar primordium|rostral rhombic lip|cerebellar anlage|cerebellum primordium|future cerebellum|dorsal part of alar plate of metencephalon|presumptive cerebellum the posterior section of the developing metencephalon recognized transiently within the vertebrate embryo; the rhombic lip extends posteriorly from the roof of the fourth ventricle to dorsal neuroepithelial cell and can be divided into eight structural units based on rhombomeres 1-8 (r1-r8), recognized at early stages of hindbrain development; producing granule cells and five brainstem nuclei, the rhombic lip plays an important role in developing a complex cerebellar neural system UBERON:0006214 carpus pre-cartilage condensation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006214 carpal pre-cartilage condensation A pre-cartilage condensation that has the potential to develop into a carpal bone. PO:0025268 fruit septum biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025268 septo del fruto (Spanish, exact)|fruit dissepiment (broad)|果実隔壁 (Japanese, exact) A septum that divides a cavity or mass of tissue in a fruit and develops from an ovary septum. PO:0025267 fruit replum biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025267 果実隔膜 (Japanese, exact)|replum del fruto (Spanish, exact)|fruit dissepiment (broad) A portion of fruit placenta tissue (PO:0004535) that divides a fruit (PO:0009001) into two or more chambers and develops from a plant ovary replum (PO:0025272). UBERON:0006213 carpus cartilage element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006213 carpal cartilage condensation A cartilaginous condensation that has the potential to develop into a carpal bone. GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004367 KEGG_REACTION:R00842|MetaCyc:1.1.1.8-RXN|Reactome:R-HSA-75889|EC:1.1.1.8|RHEA:11092 glycerol-3-phosphate dehydrogenase (NAD) activity|L-glycerophosphate dehydrogenase activity|NAD-dependent glycerol phosphate dehydrogenase activity|NAD-alpha-glycerophosphate dehydrogenase activity|glycerol phosphate dehydrogenase (NAD) activity|alpha-glycerophosphate dehydrogenase (NAD) activity|glycerol 1-phosphate dehydrogenase activity|L-glycerol phosphate dehydrogenase activity|hydroglycerophosphate dehydrogenase activity|L-alpha-glycerophosphate dehydrogenase activity|alpha-glycerol phosphate dehydrogenase (NAD) activity|NAD-linked glycerol 3-phosphate dehydrogenase activity|NADH-dihydroxyacetone phosphate reductase activity|glycerophosphate dehydrogenase (NAD) activity|L-alpha-glycerol phosphate dehydrogenase activity|NAD-L-glycerol-3-phosphate dehydrogenase activity|NAD-dependent glycerol-3-phosphate dehydrogenase activity Catalysis of the reaction: sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH + H+. GO:0004366 glycerol-3-phosphate O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004366 Reactome:R-HSA-549112|MetaCyc:RXN-1381|RHEA:15325|Reactome:R-HSA-75886|Reactome:R-HSA-1482695|EC:2.3.1.15 sn-glycerol-3-phosphate acyltransferase activity|3-glycerophosphate acyltransferase activity|acyl-CoA:sn-glycerol-3-phosphate 1-O-acyltransferase activity|glycerophosphate acyltransferase activity|glycerol phosphate transacylase activity|sn-glycerol 3-phosphate acyltransferase activity|ACP:sn-glycerol-3-phosphate acyltransferase activity|glycerol phosphate acyltransferase activity|glycerophosphate transacylase activity|alpha-glycerophosphate acyltransferase activity|glycerol 3-phosphate acyltransferase activity Catalysis of the reaction: acyl-CoA + sn-glycerol 3-phosphate = CoA + 1-acyl-sn-glycerol 3-phosphate. GO:0004369 glycerol-3-phosphate oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004369 KEGG_REACTION:R00846|EC:1.1.3.21|RHEA:18369|MetaCyc:GLYCEROL-3-PHOSPHATE-OXIDASE-RXN sn-glycerol-3-phosphate:oxygen 2-oxidoreductase activity|glycerol-1-phosphate oxidase activity|glycerol phosphate oxidase activity|alpha-glycerophosphate oxidase activity|L-alpha-glycerophosphate oxidase activity|L-alpha-glycerol-3-phosphate oxidase activity Catalysis of the reaction: sn-glycerol 3-phosphate + O(2) = glycerone phosphate + H(2)O(2). GO:0004368 glycerol-3-phosphate dehydrogenase (quinone) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004368 MetaCyc:RXN0-5260|RHEA:18977|EC:1.1.5.3|Reactome:R-HSA-188467|MetaCyc:RXN-9927 FAD-dependent glycerol-3-phosphate dehydrogenase|flavin-linked glycerol-3-phosphate dehydrogenase|sn-glycerol-3-phosphate dehydrogenase activity|glycerol-3-phosphate CoQ reductase|glycerophosphate dehydrogenase activity|sn-glycerol-3-phosphate:quinone oxidoreductase activity|L-glycerophosphate dehydrogenase activity Catalysis of the reaction: sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol. GO:0004363 glutathione synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004363 MetaCyc:GLUTATHIONE-SYN-RXN|Reactome:R-HSA-174394|RHEA:13557|KEGG_REACTION:R00497|EC:6.3.2.3|Reactome:R-HSA-5602901 GSH synthetase activity|glutathione synthetase activity|gamma-L-glutamyl-L-cysteine:glycine ligase (ADP-forming) Catalysis of the reaction: L-gamma-glutamyl-L-cysteine + ATP + glycine = ADP + glutathione + 2 H(+) + phosphate. GO:0004362 glutathione-disulfide reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004362 EC:1.8.1.7|RHEA:11740|Reactome:R-HSA-3323079|MetaCyc:GLUTATHIONE-REDUCT-NADPH-RXN|Reactome:R-HSA-71682 GSSG reductase activity|oxidized glutathione reduction|NADPH-GSSG reductase activity|NADPH-glutathione reductase activity|glutathione-disulphide reductase activity|NADPH:oxidized-glutathione oxidoreductase activity|glutathione reductase activity|glutathione S-reductase activity|glutathione:NADP+ oxidoreductase activity|glutathione reductase (NADPH) activity|GSH reductase activity Catalysis of the reaction: 2 glutathione + NADP+ = glutathione disulfide + NADPH + H+. GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004365 EC:1.2.1.12|Reactome:R-HSA-70449|Reactome:R-HSA-70482|RHEA:10300|MetaCyc:GAPOXNPHOSPHN-RXN GAPDH activity|triosephosphate dehydrogenase activity|NADH-glyceraldehyde phosphate dehydrogenase activity|NAD-dependent glyceraldehyde-3-phosphate dehydrogenase activity|glyceraldehyde phosphate dehydrogenase (NAD)|phosphoglyceraldehyde dehydrogenase activity|NAD-dependent glyceraldehyde phosphate dehydrogenase activity|glyceraldehyde-3-P-dehydrogenase activity|D-glyceraldehyde-3-phosphate:NAD+ oxidoreductase (phosphorylating)|3-phosphoglyceraldehyde dehydrogenase activity|dehydrogenase, glyceraldehyde phosphate Catalysis of the reaction: D-glyceraldehyde 3-phosphate + phosphate + NAD+ = 3-phospho-D-glyceroyl phosphate + NADH + H+. GO:0004364 glutathione transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004364 Reactome:R-HSA-176054|MetaCyc:GSHTRAN-RXN|Reactome:R-HSA-9026901|Reactome:R-HSA-9026780|Reactome:R-HSA-3301943|Reactome:R-HSA-9026911|Reactome:R-HSA-5423653|Reactome:R-HSA-176059|Reactome:R-HSA-9026777|EC:2.5.1.18 glutathione S-aryltransferase activity|S-(hydroxyalkyl)glutathione lyase activity|glutathione S-transferase activity|glutathione S-alkyltransferase activity|glutathione conjugation reaction|RX:glutathione R-transferase activity|glutathione S-alkyl transferase activity|glutathione S-aralkyltransferase activity Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. GO:0004361 glutaryl-CoA dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004361 UM-BBD_reactionID:r0198|EC:1.3.8.6|RHEA:13389|MetaCyc:GLUTARYL-COA-DEHYDROGENASE-RXN|Reactome:R-HSA-71046 glutaryl-CoA:acceptor 2,3-oxidoreductase (decarboxylating)|glutaryl coenzyme A dehydrogenase activity|glutaryl-CoA:(acceptor) 2,3-oxidoreductase (decarboxylating) Catalysis of the reaction: glutaryl-CoA + acceptor = crotonoyl-CoA + CO2 + reduced acceptor. GO:0102911 (-)-secoisolariciresinol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102911 MetaCyc:RXN-8680 Catalysis of the reaction: (-)-secoisolariciresinol + NAD <=> H+ + (-)-lactol + NADH. GO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004360 Reactome:R-HSA-449715|RHEA:13237|MetaCyc:L-GLN-FRUCT-6-P-AMINOTRANS-RXN|Reactome:R-HSA-4085027|KEGG_REACTION:R00768|EC:2.6.1.16 L-glutamine-D-fructose-6-phosphate amidotransferase activity|glucosamine-6-phosphate synthase activity|glucosamine-6-phosphate isomerase (glutamine-forming) activity|glucosamine--fructose-6-phosphate aminotransferase (isomerizing) activity|L-glutamine:D-fructose-6-phosphate isomerase (deaminating)|GlcN6P synthase activity|hexosephosphate aminotransferase activity|glucosamine 6-phosphate synthase activity|D-fructose-6-phosphate amidotransferase activity|glucosaminephosphate isomerase Catalysis of the reaction: beta-D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate. GO:0102910 dirigent protein activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102910 MetaCyc:RXN-8677 Catalysis of the reaction: 2 H+ + 2 coniferol + O2 <=> (+)-pinoresinol + 2 H2O. GO:0102913 3-aminomethylindole N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102913 MetaCyc:RXN-8686|RHEA:52268 Catalysis of the reaction: indol-3-ylmethylamine + S-adenosyl-L-methionine = H+ + N-methyl-3-aminomethylindole + S-adenosyl-L-homocysteine. GO:0102912 (-)-lactol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102912 MetaCyc:RXN-8681 Catalysis of the reaction: (-)-lactol + NAD <=> H+ + (-)-matairesinol + NADH. GO:0102915 piperitol synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102915 MetaCyc:RXN-8695 Catalysis of the reaction: H+ + (+)-pinoresinol + NADPH + O2 <=> (+)-piperitol + NADP + 2 H2O. GO:0102914 N-methyl-3-aminomethylindole N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102914 MetaCyc:RXN-8687|RHEA:52272 Catalysis of the reaction: N-methyl-3-aminomethylindole + S-adenosyl-L-methionine = H+ + gramine + S-adenosyl-L-homocysteine. GO:0102917 (S)-reticuline 7-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102917 EC:2.1.1.291|MetaCyc:RXN-8700|RHEA:10444 Catalysis of the reaction: (S)-reticulinium(1+) + S-adenosyl-L-methionine <=> H+ + laudanine(1+) + S-adenosyl-L-homocysteine. GO:0102916 sesamin synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102916 MetaCyc:RXN-8696 Catalysis of the reaction: H+ + (+)-piperitol + NADPH + O2 <=> (+)-sesamin + NADP + 2 H2O. GO:0102919 5,6-dimethylbenzimidazole synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102919 EC:1.13.11.79|MetaCyc:RXN-8771|RHEA:27345 Catalysis of the reaction: FMNH2 + O2 <=> 5,6-dimethylbenzimidazole + D-erythrose 4-phosphate + dialuric acid. GO:0102918 (R)-reticuline 7-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102918 EC:2.1.1.291|MetaCyc:RXN-8701|RHEA:38907 Catalysis of the reaction: (R)-reticulinium(1+) + S-adenosyl-L-methionine <=> (R)-laudanine(1+) + S-adenosyl-L-homocysteine + H+. GO:0004378 GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004378 EC:2.4.1.132|RHEA:29515|MetaCyc:2.4.1.132-RXN GDP-D-mannose:D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol 3-alpha-mannosyltransferase activity|guanosine diphosphomannose-oligosaccharide-lipid II mannosyltransferase activity|glycolipid 3-alpha-mannosyltransferase activity|mannosyltransferase II activity|GDP-mannose:glycolipid 1,3-alpha-D-mannosyltransferase activity|GDP-mannose-oligosaccharide-lipid mannosyltransferase II Catalysis of the reaction: beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + GDP-alpha-D-mannose = alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + GDP + H+. This reaction is the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->3)-D-mannosyl-D-mannose linkage. GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004377 EC:2.4.1.131|RHEA:29523|MetaCyc:2.4.1.131-RXN guanosine diphosphomannose-oligosaccharide-lipid mannosyltransferase activity|GDP-D-mannose:D-Man-alpha-(1->3)-[D-Man-alpha-(1->6)]-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol alpha-1,2-mannosyltransferase activity|glycolipid 2-alpha-mannosyltransferase activity|GDP-mannose:glycolipid 1,2-alpha-D-mannosyltransferase activity|oligosaccharide-lipid mannosyltransferase activity|GDP-mannose-oligosaccharide-lipid mannosyltransferase activity Catalysis of the reaction: an alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + 2 GDP-alpha-D-mannose = an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + 2 GDP + 2 H+. This reaction is the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->2)-D-mannosyl-D-mannose linkage. GO:0004379 glycylpeptide N-tetradecanoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004379 MetaCyc:2.3.1.97-RXN|Reactome:R-HSA-2534087|EC:2.3.1.97|RHEA:15521|Reactome:R-HSA-184392 myristoylating enzymes|myristoyl-coenzyme A:protein N-myristoyl transferase activity|myristoyl-CoA-protein N-myristoyltransferase activity|peptide N-tetradecanoyltransferase activity|peptide N-myristoyltransferase activity|tetradecanoyl-CoA:glycylpeptide N-tetradecanoyltransferase activity|protein N-myristoyltransferase activity|N-myristoyltransferase activity Catalysis of the reaction: tetradecanoyl-CoA + glycyl-peptide = CoA + N-tetradecanoylglycyl-peptide. GO:0004374 obsolete glycine cleavage system biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004374 glycine synthase|glycine cleavage system OBSOLETE. Catalysis of the reactions: glycine + lipoylprotein = S-aminomethyldihydrolipoylprotein + carbon dioxide (CO2), followed by S-aminomethyldihydrolipoylprotein + (6S)-tetrahydrofolate = dihydrolipoylprotein + (6R)-5,10-methylenetetrahydrofolate + ammonia. Made up of two components, aminomethyltransferase and glycine dehydrogenase (decarboxylating). GO:0004373 glycogen (starch) synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004373 MetaCyc:2.4.1.11-RXN|Reactome:R-HSA-3322009|Reactome:R-HSA-3322041|Reactome:R-HSA-3322001|Reactome:R-HSA-3828061|EC:2.4.1.11|RHEA:18549|Reactome:R-HSA-3858506 glycogen (starch) synthetase activity|UDPG-glycogen synthetase activity|UDP-glucose:glycogen 4-alpha-D-glucosyltransferase activity|UDP-glucose-glycogen glucosyltransferase activity|UDP-glycogen synthase activity|UDPG-glycogen transglucosylase activity|UDPglucose:glycogen 4-alpha-D-glucosyltransferase activity|uridine diphosphoglucose-glycogen glucosyltransferase activity Catalysis of the reaction: UDP-glucose + (1,4)-alpha-D-glucosyl(n) = UDP + (1,4)-alpha-D-glucosyl(n+1). GO:0004376 glycolipid mannosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004376 Reactome:R-HSA-162821|Reactome:R-HSA-162873 glycolipid mannosyl transferase activity Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-D-mannosyl-D-mannose linkage. GO:0004375 glycine dehydrogenase (decarboxylating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004375 RHEA:24304|EC:1.4.4.2|MetaCyc:GCVP-RXN|Reactome:R-HSA-5693967 glycine-cleavage complex|glycine decarboxylase activity|P-protein|glycine-cleavage complex P-protein activity|glycine:H-protein-lipoyllysine oxidoreductase (decarboxylating, acceptor-amino-methylating)|glycine:lipoylprotein oxidoreductase (decarboxylating and acceptor-aminomethylating)|protein P1|glycine cleavage system P-protein activity Catalysis of the reaction: glycine + lipoylprotein = S-aminomethyldihydrolipoylprotein + CO2. GO:0004370 glycerol kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004370 KEGG_REACTION:R00847|Reactome:R-HSA-75887|RHEA:21644|EC:2.7.1.30|MetaCyc:GLYCEROL-KIN-RXN glycerokinase activity|glycerol kinase (phosphorylating)|ATP:glycerol-3-phosphotransferase activity|GK|glyceric kinase activity|ATP:glycerol 3-phosphotransferase activity Catalysis of the reaction: ATP + glycerol = sn-glycerol 3-phosphate + ADP + 2 H(+). GO:0102920 acyl coenzyme A: isopenicillin N acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102920 MetaCyc:RXN-8809|EC:2.3.1.164 Catalysis of the reaction: octanoyl-CoA + isopenicillin N + H2O <=> H+ + coenzyme A + penicillin K + L-2-aminoadipate. GO:0102922 phenylpropanoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102922 RHEA:42488|MetaCyc:RXN-8857 Catalysis of the reaction: baccatin III + (3R)-3-amino-3-phenylpropanoyl-CoA = N-debenzoyl-(3'-RS)-2'-deoxytaxol + coenzyme A. GO:0004372 glycine hydroxymethyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004372 Reactome:R-HSA-200735|Reactome:R-HSA-5694137|MetaCyc:GLYOHMETRANS-RXN|Reactome:R-HSA-200651|Reactome:R-HSA-71249|RHEA:15481|EC:2.1.2.1 serine aldolase activity|serine hydroxymethylase activity|serine transhydroxymethylase activity|5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase activity|allothreonine aldolase activity|L-serine hydroxymethyltransferase activity|serine hydroxymethyltransferase activity Catalysis of the reaction: 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine. GO:0004371 glycerone kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004371 EC:2.7.1.29|MetaCyc:GLYCERONE-KINASE-RXN|KEGG_REACTION:R01011|RHEA:15773 acetol kinase (phosphorylating)|acetol kinase activity|dihydroxyacetone kinase activity|ATP:glycerone phosphotransferase activity Catalysis of the reaction: ATP + glycerone = ADP + glycerone phosphate + 2 H(+). GO:0102921 mannosylglycerate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102921 EC:2.4.1.269|MetaCyc:RXN-8849|RHEA:30639 Catalysis of the reaction: GDP-alpha-D-mannose + D-glycerate <=> H+ + 2-(alpha-D-mannosyl)-D-glycerate + GDP. GO:0102924 gibberellin A44,2-oxoglutarate:oxygen oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102924 MetaCyc:RXN-886 Catalysis of the reaction: 2 H+ + gibberellin A44 + 2-oxoglutarate + O2 = gibberellin A98 + succinate + carbon dioxide. GO:0102923 3'-N-debenzoyl-2'-deoxytaxol N-benzoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102923 RHEA:33687|MetaCyc:RXN-8859 Catalysis of the reaction: 3'-N-debenzoyltaxol + benzoyl-CoA = H+ + paclitaxel + coenzyme A. GO:0102926 solanidine glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102926 MetaCyc:RXN-8882 Catalysis of the reaction: UDP-alpha-D-glucose + solanidine = H+ + gamma-chaconine + UDP. GO:0102925 solanine UDP-galactose galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102925 MetaCyc:RXN-8875 Catalysis of the reaction: UDP-D-galactose + solanidine = H+ + gamma-solanine + UDP. GO:0102928 beta-solanine rhamnosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102928 MetaCyc:RXN-8884 Catalysis of the reaction: beta-solanine + UDP-L-rhamnose = solanine + UDP. GO:0102927 beta-chaconine rhamnosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102927 MetaCyc:RXN-8883 Catalysis of the reaction: beta-chaconine + UDP-L-rhamnose = H+ + alpha-chaconine + UDP. GO:0102929 lachrymatory factor synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102929 MetaCyc:RXN-8911 Catalysis of the reaction: 1-propenylsulfenate = propanethiol S-oxide. GO:0004349 glutamate 5-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004349 MetaCyc:GLUTKIN-RXN|KEGG_REACTION:R00239|RHEA:14877|EC:2.7.2.11 gamma-glutamyl kinase activity|ATP:L-glutamate 5-phosphotransferase activity|glutamate kinase activity|gamma-glutamate kinase activity|ATP:gamma-L-glutamate phosphotransferase activity|ATP-L-glutamate 5-phosphotransferase activity Catalysis of the reaction: L-glutamate + ATP = L-glutamyl 5-phosphate + ADP + H(+). GO:0004348 glucosylceramidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004348 Reactome:R-HSA-1861789|MetaCyc:GLUCOSYLCERAMIDASE-RXN|EC:3.2.1.45|RHEA:13269|Reactome:R-HSA-1861788|Reactome:R-HSA-1605591 glucocerebrosidase activity|glucosphingosine glucosylhydrolase activity|psychosine hydrolase activity|beta-D-glucocerebrosidase activity|GlcCer-beta-glucosidase activity|glucosylsphingosine beta-D-glucosidase activity|beta-glucosylceramidase activity|D-glucosyl-N-acylsphingosine glucohydrolase activity|glucosylcerebrosidase activity|acid beta-glucosidase activity|glucosylsphingosine beta-glucosidase activity|ceramide glucosidase activity|beta-glucocerebrosidase activity Catalysis of the reaction: D-glucosyl-N-acylsphingosine + H2O = D-glucose + N-acylsphingosine. GO:0004345 glucose-6-phosphate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004345 MetaCyc:GLU6PDEHYDROG-RXN|RHEA:15841|Reactome:R-HSA-70377|EC:1.1.1.49 NADP-dependent glucose 6-phosphate dehydrogenase activity|Zwischenferment|glucose 6-phosphate dehydrogenase (NADP) activity|6-phosphoglucose dehydrogenase activity|glucose-6-phosphate 1-dehydrogenase activity|D-glucose 6-phosphate dehydrogenase activity|zwischenferment|D-glucose-6-phosphate:NADP+ 1-oxidoreductase activity|GDH|G6PDH|6-phosphoglucose dehydrogenas|NADP-glucose-6-phosphate dehydrogenase activity|G6PD activity|Entner-doudoroff enzyme Catalysis of the reaction: D-glucose 6-phosphate + NADP+ = D-glucono-1,5-lactone 6-phosphate + NADPH + H+. GO:0004344 glucose dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004344 KEGG_REACTION:R00305|MetaCyc:GLUCOSE-DEHYDROGENASE-ACCEPTOR-RXN|RHEA:24540|EC:1.1.99.10 glucose dehydrogenase (Aspergillus) activity|glucose dehydrogenase (decarboxylating)|D-glucose:(acceptor) 1-oxidoreductase|D-glucose:acceptor 1-oxidoreductase|glucose dehydrogenase (acceptor) activity Catalysis of the reaction: D-glucose + acceptor = D-glucono-1,5-lactone + reduced acceptor. GO:0004347 glucose-6-phosphate isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004347 RHEA:11816|MetaCyc:PGLUCISOM-RXN|Reactome:R-HSA-70475|EC:5.3.1.9|Reactome:R-HSA-70471 oxoisomerase activity|hexosephosphate isomerase activity|phosphohexomutase activity|D-glucose-6-phosphate aldose-ketose-isomerase activity|phosphoglucoisomerase activity|hexose phosphate isomerase activity|phosphohexose isomerase activity|hexose monophosphate isomerase activity|D-glucose-6-phosphate ketol-isomerase activity|glucose phosphate isomerase activity|phosphosaccharomutase activity|phosphoglucose isomerase activity|phosphohexoisomerase activity Catalysis of the reaction: D-glucose 6-phosphate = D-fructose 6-phosphate. GO:0004346 glucose-6-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004346 Reactome:R-HSA-3266566|Reactome:R-HSA-3282876|KEGG_REACTION:R00303|Reactome:R-HSA-3274540|Reactome:R-HSA-3262512|RHEA:16689|EC:3.1.3.9|Reactome:R-HSA-71825|MetaCyc:GLUCOSE-6-PHOSPHATASE-RXN D-glucose-6-phosphate phosphohydrolase activity|glucose 6-phosphate phosphatase activity Catalysis of the reaction: D-glucopyranose 6-phosphate + H2O = D-glucose + phosphate. D-glucopyranose is also known as D-glucose 6-phosphate. GO:0004341 gluconolactonase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004341 MetaCyc:GLUCONOLACT-RXN|RHEA:10440|EC:3.1.1.17 lactonase activity|aldonolactonase activity|D-glucono-1,5-lactone lactonohydrolase activity|gulonolactonase activity|glucono-delta-lactonase activity Catalysis of the reaction: D-glucono-1,5-lactone + H2O = D-gluconate. GO:0004340 glucokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004340 Reactome:R-HSA-70420|RHEA:17825|EC:2.7.1.2|Reactome:R-HSA-5621918|MetaCyc:GLUCOKIN-RXN|Reactome:R-HSA-5621888 glucokinase (phosphorylating)|glucose kinase activity|ATP:D-glucose 6-phosphotransferase activity Catalysis of the reaction: ATP + D-glucose = ADP + D-glucose-6-phosphate. GO:0004343 glucosamine 6-phosphate N-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004343 Reactome:R-HSA-449734|KEGG_REACTION:R02058|EC:2.3.1.4|RHEA:10292|MetaCyc:GLUCOSAMINEPNACETYLTRANS-RXN N-acetylglucosamine-6-phosphate synthase activity|phosphoglucosamine transacetylase activity|aminodeoxyglucosephosphate acetyltransferase activity|acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase activity|D-glucosamine-6-P N-acetyltransferase activity|glucosamine-6-phosphate acetylase activity|phosphoglucosamine acetylase activity|phosphoglucosamine N-acetylase activity|glucosamine 6-phosphate acetylase activity|glucosamine-phosphate N-acetyltransferase activity Catalysis of the reaction: D-glucosamine 6-phosphate + acetyl-CoA = N-acetyl-D-glucosamine 6-phosphate + CoA + H(+). GO:0004342 glucosamine-6-phosphate deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004342 KEGG_REACTION:R00765|Reactome:R-HSA-6799604|MetaCyc:GLUCOSAMINE-6-P-DEAMIN-RXN|RHEA:12172|EC:3.5.99.6 2-amino-2-deoxy-D-glucose-6-phosphate aminohydrolase (ketol isomerizing)|glucosamine-6-phosphate isomerase activity|glucosaminephosphate isomerase|phosphoglucosaminisomerase activity|glucosamine phosphate deaminase activity|aminodeoxyglucosephosphate isomerase activity|phosphoglucosamine isomerase activity|GlcN6P deaminase activity Catalysis of the reaction: D-glucosamine 6-phosphate + H(2)O = beta-D-fructose 6-phosphate + NH(4)(+). GO:0102931 (Z,E)-alpha- farnesene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102931 MetaCyc:RXN-8931 Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (Z,E)-alpha-farnesene + diphosphoric acid. GO:0102930 4-hydroxybenzoate geranyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102930 MetaCyc:RXN-8920|RHEA:27854|EC:2.5.1.93 Catalysis of the reaction: geranyl diphosphate + 4-hydroxybenzoic acid = 3-geranyl-4-hydroxybenzoate + diphosphoric acid. GO:0102933 GDP-4-dehydro-6-deoxy-D-mannose-4-aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102933 MetaCyc:RXN-8953|RHEA:36779|EC:2.6.1.102 Catalysis of the reaction: GDP-4-amino-4,6-dideoxy-alpha-D-mannose + 2-oxoglutarate = GDP-4-dehydro-6-deoxy-alpha-D-mannose + L-glutamate. GO:0102932 pterocarpan reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102932 MetaCyc:RXN-8936 Catalysis of the reaction: H+ + (-)-medicarpin + NADPH = (+)-vestitol + NADP. GO:0102935 gypsogenin-UDP-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102935 MetaCyc:RXN-9012 Catalysis of the reaction: UDP-alpha-D-glucose + gypsogenin = gypsogenin-28-beta-D-glucoside + UDP. GO:0102934 costunolide synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102934 EC:1.14.14.150|MetaCyc:RXN-8971|RHEA:28230 Catalysis of the reaction: germacra-1(10),4,11(13)-trien-12-oate + O2 + NADPH + 2 H+ = costunolide + 2 H2O + NADP. GO:0018989 apolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018989 Wikipedia:Apolysis The first process of molting, characterized by the detachment of the old cuticle from the underlying epidermal cells. GO:0102937 16-alpha-hydroxygypsogenate-UDP-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102937 MetaCyc:RXN-9014 Catalysis of the reaction: UDP-alpha-D-glucose + 16-alpha-hydroxygypsogenate = 16-alpha-hydroxygypsogenate-28-beta-D-glucoside + UDP. GO:0102936 gypsogenate-UDP-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102936 MetaCyc:RXN-9013 Catalysis of the reaction: UDP-alpha-D-glucose + gypsogenate = gypsogenate-28-beta-D-glucoside + UDP. GO:0102939 3-methoxy-5-hydroxytoluene O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102939 MetaCyc:RXN-9018 Catalysis of the reaction: 3-methoxy-5-hydroxytoluene + S-adenosyl-L-methionine = H+ + 3,5-dimethoxytoluene + S-adenosyl-L-homocysteine. GO:0018986 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018986 GO:0102938 orcinol O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102938 MetaCyc:RXN-9017|EC:2.1.1.6 Catalysis of the reaction: orcinol + S-adenosyl-L-methionine = H+ + 3-methoxy-5-hydroxytoluene + S-adenosyl-L-homocysteine. GO:0018985 pronuclear envelope synthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018985 Synthesis and ordering of the envelope of pronuclei. GO:0018988 obsolete molting cycle, protein-based cuticle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018988 protein-based cuticle molting cycle OBSOLETE. The periodic shedding of part or all of a protein-based cuticle, which is then replaced by a new protein-based cuticle. A cuticle is the outer layer of an animal which acts to prevent water loss. GO:0018987 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018987 GO:0018982 vanillin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018982 UM-BBD_pathwayID:van vanillic aldehyde metabolic process|vanillin metabolism|vanillic aldehyde metabolism The chemical reactions and pathways involving vanillin, an aromatic hydrocarbon which occurs naturally in black vanilla bean pods and can be obtained as a by-product of the pulp and paper industry by the oxidative breakdown of lignin. GO:0018981 triethanolamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018981 UM-BBD_pathwayID:tea triethanolamine metabolism The chemical reactions and pathways involving triethanolamine, a combustible, hygroscopic, colorless liquid commonly used in dry-cleaning solutions, cosmetics, detergents, textile processing, wool scouring, and as a corrosion inhibitor and pharmaceutical alkalizing agent. GO:0018984 naphthalenesulfonate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018984 UM-BBD_pathwayID:nphs naphthalenesulphonate metabolic process|naphthalenesulphonate metabolism|naphthalenesulfonate metabolism The chemical reactions and pathways involving naphthalenesulfonate, sulfonated derivatives of naphthalene. GO:0018983 Z-phenylacetaldoxime metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018983 UM-BBD_pathwayID:pao Z-phenylacetaldoxime metabolism The chemical reactions and pathways involving Z-phenylacetaldoxime, a member of the glucosinolate group of compounds, a class of natural products that are gaining increasing interest as cancer-preventing agents and crop protectants. GO:0018980 2,4,5-trichlorophenoxyacetic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018980 UM-BBD_pathwayID:2,4,5-t 2,4,5-trichlorophenoxyacetic acid metabolism|2,4,5-T metabolism|2,4,5-T metabolic process The chemical reactions and pathways involving 2,4,5-trichlorophenoxyacetic acid, a chlorinated aromatic compound which is widely used as a herbicide, often as a weed killer for home lawns. GO:0004359 glutaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004359 EC:3.5.1.2|MetaCyc:GLUTAMIN-RXN|Reactome:R-HSA-70609|RHEA:15889 L-glutaminase activity|L-glutamine amidohydrolase activity|glutaminase I|glutamine aminohydrolase activity Catalysis of the reaction: L-glutamine + H2O = L-glutamate + NH3. GO:0004356 glutamate-ammonia ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004356 MetaCyc:GLUTAMINESYN-RXN|Reactome:R-HSA-70606|KEGG_REACTION:R00253|RHEA:16169|EC:6.3.1.2 L-glutamate:ammonia ligase (ADP-forming)|glutamylhydroxamic synthetase activity|L-glutamine synthetase activity|glutamine synthetase activity Catalysis of the reaction: L-glutamate + ATP + NH(3) = L-glutamine + ADP + 2 H(+) + phosphate. GO:0004355 glutamate synthase (NADPH) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004355 MetaCyc:GLUGLNSYN-PWY|MetaCyc:GLUTSYN-PWY|MetaCyc:GLUTAMATESYN-RXN|EC:1.4.1.13|KEGG_REACTION:R00114|RHEA:15501 L-glutamate:NADP+ oxidoreductase (transaminating)|glutamine-ketoglutaric aminotransferase activity|L-glutamate synthetase activity|NADPH GOGAT|glutamate (reduced nicotinamide adenine dinucleotide phosphate) synthase activity|L-glutamine:2-oxoglutarate aminotransferase, NADPH oxidizing activity|NADPH-linked glutamate synthase|GOGAT activity|NADPH-glutamate synthase activity|NADPH-dependent glutamate synthase activity|glutamate synthetase (NADP) activity|L-glutamate synthase activity|glutamine amide-2-oxoglutarate aminotransferase (oxidoreductase, NADP) activity Catalysis of the reaction: 2 L-glutamate + NADP(+) = 2-oxoglutarate + L-glutamine + H(+) + NADPH. This is a two-step reaction: (a) L-glutamate + NH3 = L-glutamine + H2O, (b) L-glutamate + NADP+ + H2O = NH3 + 2-oxoglutarate + NADPH + H+. GO:0004358 glutamate N-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004358 KEGG_REACTION:R02282|MetaCyc:GLUTAMATE-N-ACETYLTRANSFERASE-RXN|EC:2.3.1.35|RHEA:15349 glutamate acetyltransferase activity|acetylglutamate synthetase activity|2-N-acetyl-L-ornithine:L-glutamate N-acetyltransferase activity|acetylglutamate-acetylornithine transacetylase activity|N-acetylglutamate synthetase activity|acetylornithine glutamate acetyltransferase activity|ornithine acetyltransferase activity|N-acetyl-L-glutamate synthetase activity|N2-acetyl-L-ornithine:L-glutamate N-acetyltransferase activity|ornithine transacetylase activity|acetylglutamic synthetase activity|acetylglutamic-acetylornithine transacetylase activity|acetylornithinase activity|N-acetylglutamate synthase activity|alpha-N-acetyl-L-ornithine:L-glutamate N-acetyltransferase activity Catalysis of the reaction: N(2)-acetyl-L-ornithine + L-glutamate = N-acetyl-L-glutamate + L-ornithine. GO:0004357 glutamate-cysteine ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004357 RHEA:13285|MetaCyc:GLUTCYSLIG-RXN|Reactome:R-HSA-5602892|KEGG_REACTION:R00894|Reactome:R-HSA-174367|EC:6.3.2.2 gamma-glutamyl-L-cysteine synthetase activity|L-glutamate:L-cysteine gamma-ligase (ADP-forming) activity|gamma-glutamylcysteinyl synthetase activity|gamma-glutamylcysteine synthetase activity Catalysis of the reaction: L-cysteine + L-glutamate + ATP = L-gamma-glutamyl-L-cysteine + ADP + 2 H(+) + phosphate. GO:0004352 glutamate dehydrogenase (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004352 EC:1.4.1.2|MetaCyc:GLUTAMATE-DEHYDROGENASE-RXN|RHEA:15133 NAD-dependent glutamate dehydrogenase activity|NAD-glutamate dehydrogenase activity|NAD-dependent glutamic dehydrogenase activity|NAD:glutamate oxidoreductase activity|glutamate dehydrogenase (NAD)|L-glutamate:NAD+ oxidoreductase (deaminating)|NAD-specific glutamate dehydrogenase activity|glutamic dehydrogenase activity|L-glutamate dehydrogenase|NADH-linked glutamate dehydrogenase activity|NAD-linked glutamic dehydrogenase activity|NAD-linked glutamate dehydrogenase activity|NAD-specific glutamic dehydrogenase activity|glutamic acid dehydrogenase|glutamate oxidoreductase activity Catalysis of the reaction: L-glutamate + H2O + NAD+ = 2-oxoglutarate + NH3 + NADH + H+. GO:0004351 glutamate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004351 EC:4.1.1.15|Reactome:R-HSA-888572|MetaCyc:GLUTDECARBOX-RXN|Reactome:R-HSA-888577|RHEA:17785 gamma-glutamate decarboxylase activity|L-glutamate 1-carboxy-lyase (4-aminobutanoate-forming)|L-glutamic decarboxylase activity|L-aspartate-alpha-decarboxylase activity|L-glutamate alpha-decarboxylase activity|L-glutamic acid decarboxylase activity|cysteic acid decarboxylase activity|aspartic alpha-decarboxylase|L-glutamate 1-carboxy-lyase activity Catalysis of the reaction: L-glutamate = 4-aminobutanoate + CO2. GO:0004354 glutamate dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004354 EC:1.4.1.4|MetaCyc:GLUTSYNIII-PWY|MetaCyc:GLUTDEHYD-RXN|RHEA:11612 NAD(P)-glutamate dehydrogenase activity|L-glutamate:NADP+ oxidoreductase (deaminating)|NAD(P)H-dependent glutamate dehydrogenase activity|L-glutamate dehydrogenase|glutamic dehydrogenase activity|L-glutamic acid dehydrogenase activity|dehydrogenase, glutamate (nicotinamide adenine dinucleotide (phosphate))|glutamic acid dehydrogenase Catalysis of the reaction: L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH + H+. GO:0102940 phloroglucinol O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102940 MetaCyc:RXN-9020 Catalysis of the reaction: phloroglucinol + S-adenosyl-L-methionine = H+ + 3,5-dihydroxyanisole + S-adenosyl-L-homocysteine. GO:0004353 glutamate dehydrogenase [NAD(P)+] activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004353 EC:1.4.1.3|Reactome:R-HSA-70589|MetaCyc:GLUTAMATE-DEHYDROGENASE-NADP+-RXN|MetaCyc:GLUTAMATE-SYN2-PWY|Reactome:R-HSA-70600 glutamic dehydrogenase activity|L-glutamate:NAD(P)+ oxidoreductase (deaminating)|glutamate biosynthesis, using glutamate dehydrogenase (NAD(P)+)|glutamate biosynthetic process, using glutamate dehydrogenase (NAD(P)+) Catalysis of the reaction: L-glutamate + H2O + NAD(P)+ = 2-oxoglutarate + NH3 + NAD(P)H + H+. GO:0102942 3,5-dimethoxyphenol O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102942 MetaCyc:RXN-9022 Catalysis of the reaction: 3,5-dimethoxyphenol + S-adenosyl-L-methionine = H+ + 1,3,5-trimethoxybenzene + S-adenosyl-L-homocysteine. GO:0102941 3,5-dihydroxyanisole O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102941 MetaCyc:RXN-9021 Catalysis of the reaction: 3,5-dihydroxyanisole + S-adenosyl-L-methionine = H+ + 3,5-dimethoxyphenol + S-adenosyl-L-homocysteine. GO:0004350 glutamate-5-semialdehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004350 RHEA:19541|MetaCyc:GLUTSEMIALDEHYDROG-RXN|EC:1.2.1.41|KEGG_REACTION:R03313 glutamyl-gamma-semialdehyde dehydrogenase activity|glutamate-phosphate reductase activity|glutamate-gamma-semialdehyde dehydrogenase activity|gamma-glutamylphosphate reductase activity|glutamylphosphate reductase activity|L-glutamate-5-semialdehyde:NADP+ 5-oxidoreductase (phosphorylating)|glutamate semialdehyde dehydrogenase activity|beta-glutamylphosphate reductase activity|gamma-glutamyl phosphate reductase activity Catalysis of the reaction: L-glutamate 5-semialdehyde + NADP(+) + phosphate = L-glutamyl 5-phosphate + H(+) + NADPH. GO:0102944 medicagenate UDP-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102944 MetaCyc:RXN-9035 Catalysis of the reaction: UDP-alpha-D-glucose(2-) + medicagenate <=> UDP(3-) + a medicagenate monoglucoside. GO:0102943 trans-2,3-dihydro-3-hydroxy-anthranilate isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102943 RHEA:28182|EC:5.3.3.17|MetaCyc:RXN-9031 Catalysis of the reaction: (2S,3S)-2,3-dihydro-3-hydroxyanthranilic acid = (1R,6S)-6-ammonio-5-oxocyclohex-2-ene-1-carboxylate. GO:0102946 soyasapogenol E UDP-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102946 MetaCyc:RXN-9038 Catalysis of the reaction: UDP-alpha-D-glucose + soyasapogenol E <=> UDP + a soyasapogenol E monoglucoside. GO:0102945 soyasapogenol B UDP-glucosyl transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102945 MetaCyc:RXN-9037 Catalysis of the reaction: UDP-alpha-D-glucose(2-) + soyasapogenol B <=> UDP(3-) + a soyasapogenol B monoglucoside. CHEBI:53291 2-halophenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_53291 GO:0102948 luteolin C-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102948 MetaCyc:RXN-9081 Catalysis of the reaction: 2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxo-4H-chromen-7-olate luteolin-7-olate + a glucosylated glucose acceptor = isoorientin + a non glucosylated glucose acceptor. GO:0102947 (+)-delta-cadinene-8-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102947 MetaCyc:RXN-9045 Catalysis of the reaction: H+ + (+)-delta-cadinene + NADPH + O2 <=> 8-hydroxy-(+)-delta-cadinene + NADP + H2O. GO:0018997 obsolete electron transfer carrier biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018997 electron transfer carrier OBSOLETE. (Was not defined before being made obsolete). GO:0018996 molting cycle, collagen and cuticulin-based cuticle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018996 collagen and cuticulin-based cuticle molting cycle The periodic shedding of part or all of a collagen and cuticulin-based cuticle, which is then replaced by a new collagen and cuticulin-based cuticle. An example of this is found in the Nematode worm, Caenorhabditis elegans. GO:0102949 1,2-rhamnosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102949 MetaCyc:RXN-9082 Catalysis of the reaction: isoorientin + an L-rhamonsylated rhamnosyl acceptor = isoorientin 2'-O-rhamnoside + a non rhamnosylated rhamnosyl acceptor. GO:0018999 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018999 GO:0018998 obsolete metaxin biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0018998 metaxin OBSOLETE. (Was not defined before being made obsolete). GO:0018993 somatic sex determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018993 The determination of sex and sexual phenotypes in an organism's soma. GO:0018992 germ-line sex determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018992 The determination of sex and sexual phenotype in an organism's germ line. GO:0018995 host cellular component biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0018995 Wikipedia:Host_(biology) host organism Any cellular component of a host cell. The host is an organism in which another organism, for instance a parasite or symbiont, spends part or all of its life cycle and from which it obtains nourishment and/or protection. GO:0018994 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018994 GO:0018991 oviposition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018991 Wikipedia:Oviposition egg laying|post-mating oviposition|egg-laying The deposition of eggs (either fertilized or not) upon a surface or into a medium such as water. GO:0018990 ecdysis, chitin-based cuticle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018990 The shedding of the old chitin-based cuticlar fragments during the molting cycle. An example of this is found in Drosophila melanogaster. PO:0025222 reproductive shoot apex biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025222 ápice reproductivo del epiblasto (epiblastema) (Spanish, exact)|生殖シュート頂、茎頂 (Japanese, exact) A shoot apex that has as part a reproductive shoot apical meristem. GO:0004327 obsolete formaldehyde dehydrogenase (glutathione) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004327 formaldehyde dehydrogenase (glutathione) activity OBSOLETE. Catalysis of the reaction: formaldehyde + glutathione + NAD+ = S-formylglutathione + NADH + H+. GO:0004326 tetrahydrofolylpolyglutamate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004326 Reactome:R-HSA-200682|Reactome:R-HSA-197958|EC:6.3.2.17|Reactome:R-HSA-200681|RHEA:10580|MetaCyc:FOLYLPOLYGLUTAMATESYNTH-RXN folylpolyglutamate synthase activity|FPGS activity|tetrahydropteroyl-[gamma-polyglutamate]:L-glutamate gamma-ligase (ADP-forming)|folate polyglutamate synthetase activity|folylpolyglutamyl synthetase activity|folylpoly-gamma-glutamate synthetase-dihydrofolate synthetase activity|folylpoly(gamma-glutamate) synthase activity|folylpoly-gamma-glutamate synthase activity|formyltetrahydropteroyldiglutamate synthetase activity|N10-formyltetrahydropteroyldiglutamate synthetase activity|folylpolyglutamate synthetase activity|tetrahydrofolyl-[gamma-Glu]n:L-glutamate gamma-ligase (ADP-forming)|N(10)-formyltetrahydropteroyldiglutamate synthetase activity|tetrahydrofolate synthase activity|tetrahydrofolate:L-glutamate gamma-ligase (ADP-forming) activity Catalysis of the reaction: ATP + tetrahydrofolyl-(Glu)(n) + L-glutamate = ADP + phosphate + tetrahydrofolyl-(Glu)(n+1). GO:0004329 formate-tetrahydrofolate ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004329 Reactome:R-HSA-5696839|MetaCyc:FORMATETHFLIG-RXN|RHEA:20221|EC:6.3.4.3|Reactome:R-HSA-6801456|Reactome:R-HSA-200711 10-formyltetrahydrofolate synthetase activity|tetrahydrofolic formylase activity|formyltetrahydrofolate synthetase activity|tetrahydrofolate formylase activity|formate:tetrahydrofolate ligase (ADP-forming)|10-formyl-THF synthetase activity Catalysis of the reaction: ATP + formate + tetrahydrofolate = ADP + phosphate + 10-formyltetrahydrofolate. GO:0004328 formamidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004328 RHEA:21948|EC:3.5.1.49|MetaCyc:FORMAMIDASE-RXN|KEGG_REACTION:R00524|UM-BBD_reactionID:r0873 formamide amidohydrolase activity|formamide hydrolase activity Catalysis of the reaction: formamide + H(2)O = formate + NH(4)(+). GO:0004323 obsolete multicopper ferroxidase iron transport mediator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004323 multicopper ferroxidase iron transport mediator activity OBSOLETE. Catalysis of the reaction: 4 Fe2+ + 4 H+ + O2 = 4 Fe3+ + 2 H2O. GO:0004322 ferroxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004322 Reactome:R-HSA-1562603|Reactome:R-HSA-917891|MetaCyc:RXN0-1483|RHEA:11149|Reactome:R-HSA-5691107|Reactome:R-HSA-917933|Reactome:R-HSA-5621402|EC:1.16.3.1|Reactome:R-HSA-1562626|Reactome:R-HSA-1562604 ferroxidase I|Fe(II):oxygen oxidoreductase activity|multicopper ferroxidase iron transport mediator activity|hephaestin|ceruloplasmin|iron(II): oxygen oxidoreductase activity|HEPH|ferro:O2 oxidoreductase activity|ferroxidase, iron II:oxygen oxidoreductase activity|caeruloplasmin Catalysis of the reaction: 4 Fe2+ + 4 H+ + O2 = 4 Fe3+ + 2 H2O. GO:0004325 ferrochelatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004325 Reactome:R-HSA-189465|KEGG_REACTION:R00310|RHEA:22584|MetaCyc:PROTOHEMEFERROCHELAT-RXN|EC:4.99.1.1 protoheme ferro-lyase (protoporphyrin-forming)|protoheme ferro-lyase activity|ferro-protoporphyrin chelatase activity|heme synthetase activity|protoheme ferrolyase activity|iron chelatase activity|heme synthase activity Catalysis of the reaction: protoheme = Fe(2+) + protoporphyrin IX. GO:0004324 ferredoxin-NADP+ reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004324 MetaCyc:1.18.1.2-RXN|RHEA:20125|EC:1.18.1.2 reduced nicotinamide adenine dinucleotide phosphate-adrenodoxin reductase activity|ferredoxin-NADP-oxidoreductase activity|TPNH-ferredoxin reductase activity|ferredoxin-NADP reductase activity|ferredoxin-nicotinamide-adenine dinucleotide phosphate (oxidized) reductase activity|NADP:ferredoxin oxidoreductase activity|ferredoxin-TPN reductase activity|ferredoxin-nicotinamide adenine dinucleotide phosphate reductase activity|ferredoxin-NADP oxidoreductase activity|ferredoxin:NADP+ oxidoreductase activity|NADPH:ferredoxin oxidoreductase activity Catalysis of the reaction: reduced ferredoxin + NADP+ = oxidized ferredoxin + NADPH + H+. GO:0004321 fatty-acyl-CoA synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004321 EC:2.3.1.86|RHEA:22896|MetaCyc:FATTY-ACYL-COA-SYNTHASE-RXN yeast fatty acid synthase activity|fatty acyl CoA synthase activity|acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl- reducing) Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADH + 2n NADPH + 4n H+ = a long-chain acyl-CoA + n CoA + n CO2 + 2n NAD+ + 2n NADP+. GO:0004320 oleoyl-[acyl-carrier-protein] hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004320 EC:3.1.2.14|MetaCyc:PWY-5142|RHEA:15057|MetaCyc:3.1.2.14-RXN oleoyl-acyl-carrier-protein hydrolase|oleoyl-acyl carrier protein thioesterase activity|oleoyl-ACP thioesterase activity|oleoyl-[acyl-carrier protein] hydrolase activity|oleoyl-ACP hydrolase activity Catalysis of the reaction: oleoyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + oleate. GO:0018968 tetrahydrofuran metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018968 UM-BBD_pathwayID:thf THF metabolism|tetrahydrofuran metabolism|THF metabolic process The chemical reactions and pathways involving tetrahydrofuran, a cyclic 4 carbon ether. It is one of the most polar ethers and is a widely used solvent for polar reagents. Since THF is very soluble in water and has a relatively low boiling point, significant amounts are often released into the environment, causing contamination problems. GO:0018967 tetrachloroethylene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018967 UM-BBD_pathwayID:tce2 tetrachloroethylene metabolism|tetrachloroethene metabolic process|tetrachloroethene metabolism The chemical reactions and pathways involving tetrachloroethylene (tetrachloroethene), a derivative of ethene with the hydrogen atoms replaced by chlorines. Tetrachloroethene has been used primarily as a solvent in dry-cleaning industries and to a lesser extent as a degreasing solvent. GO:0018969 thiocyanate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018969 UM-BBD_pathwayID:thc|MetaCyc:P581-PWY thiocyanic acid metabolic process|thiocyanic acid metabolism|thiocyanate metabolism The chemical reactions and pathways involving thiocyanate, the anion of thiocyanic acid, a toxic cyanide derivative commonly formed as a by-product in the production of gas for fuel, coke, and substances for chemical industries. GO:0018964 propylene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018964 UM-BBD_pathwayID:pro propylene metabolism The chemical reactions and pathways involving propylene, an alkene produced by catalytic or thermal cracking of hydrocarbons or as a by-product of petroleum refining. It is used mainly in the preparation of alkylates for gasoline and in the production of polypropylene, acrylonitrile, propylene oxide and a number of other industrial chemicals. GO:0018963 phthalate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018963 UM-BBD_pathwayID:pth phthalic acid metabolism|phthalic acid metabolic process|phthalate metabolism The chemical reactions and pathways involving phthalate, the anion of phthalic acid. Phthalic acid diesters are used industrially in the production of a variety of household and consumer goods including plastic polymers, lubricating oils, and carriers for perfumes in cosmetics, while phthalic acid itself is used industrially as a plasticizer. Terephthalate is used in the synthesis of polyethylene terephthalate (polyethene terephthlate, abbreviated PET or PETE), a plastic polymer with many commercial uses. GO:0018966 styrene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018966 UM-BBD_pathwayID:sty styrene metabolism The chemical reactions and pathways involving styrene, an aromatic hydrocarbon liquid soluble in ether and alcohol. When heated, exposed to light or added to a peroxide catalyst, it undergoes polymerization to form polystyrene, a versatile material used in the manufacture of plastics, synthetic rubber, thermal insulation, and packaging. Styrene is a classified mutagen and a suspected carcinogen. GO:0018965 s-triazine compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018965 UM-BBD_pathwayID:tria s-triazine compound metabolism The chemical reactions and pathways involving any s-triazine compound. These compounds include many pesticides of widespread use in agriculture, and are characterized by a symmetrical hexameric ring consisting of alternating carbon and nitrogen atoms. GO:0018960 4-nitrophenol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018960 UM-BBD_pathwayID:nphe p-nitrophenol metabolic process|p-nitrophenol metabolism|4-nitrophenol metabolism The chemical reactions and pathways involving 4-nitrophenol, a nitroaromatic compound which is used in the production of dyes, leather treatment agents, fungicides and as an intermediate in the production of the insecticide parathion. GO:0018962 3-phenylpropionate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018962 UM-BBD_pathwayID:ppa phenylpropanoate metabolic process|hydrocinnamic acid metabolism|hydrocinnamic acid metabolic process|phenylpropanoate metabolism|3-phenylpropionate metabolism The chemical reactions and pathways involving 3-phenylpropionate, the anion of phenylpropanoic acid. It is produced from putrefaction of proteins in soil or breakdown of several constituents of plants, such as lignin, various oils and resins. GO:0018961 pentachlorophenol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018961 UM-BBD_pathwayID:pcp pentachlorophenol metabolism|PCP metabolic process|PCP metabolism The chemical reactions and pathways involving pentachlorophenol, a chlorinated insecticide and fungicide used primarily to protect timber from fungal rot and wood boring insects. Pentachlorophenol is significantly toxic to mammals, plants, and many microorganisms. PO:0025212 leaf pavement cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025212 葉被蓋細胞 (Japanese, exact)|célula de pavimento de la hoja (Spanish, exact) An epidermal pavement cell that is part of a leaf epidermis. GO:0004338 glucan exo-1,3-beta-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004338 MetaCyc:3.2.1.58-RXN|EC:3.2.1.58 glucan 1,3-beta-glucosidase activity|exo-beta-1,3-D-glucanase activity|exo-1,3-beta-glucosidase activity|exo (1->3)-beta-glucanase activity|exo-beta-1,3-glucanase activity|exo-1,3-beta-D-glucanase activity|beta-1,3-glucan exo-hydrolase activity|exo-beta-(1->3)-glucanohydrolase activity|1,3-beta-glucan glucohydrolase activity|exo-beta-(1->3)-D-glucanase activity|exo-1,3-beta-glucanase activity Catalysis of the successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1->3)-beta-D-glucans, releasing alpha-glucose. GO:0004337 geranyltranstransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004337 Reactome:R-HSA-191303|Reactome:R-HSA-8870469|RHEA:19361|MetaCyc:FPPSYN-RXN|EC:2.5.1.10|KEGG_REACTION:R02003 farnesylpyrophosphate synthetase activity|geranyl transferase I|farnesyl-diphosphate synthase activity|geranyltransferase activity|farnesyl diphosphate synthetase activity|farnesyl pyrophosphate synthetase activity|FPP synthetase activity|geranyl-diphosphate:isopentenyl-diphosphate geranyltranstransferase activity Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = 2-trans,6-trans-farnesyl diphosphate + diphosphate. GO:0004339 glucan 1,4-alpha-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004339 MetaCyc:3.2.1.3-RXN|EC:3.2.1.3 exo-1,4-alpha-glucosidase activity|gamma-amylase activity|1,4-alpha-D-glucan glucohydrolase activity|amyloglucosidase activity|gamma-1,4-glucan glucohydrolase activity|glucoamylase activity|glucose amylase activity|lysosomal alpha-glucosidase activity Catalysis of the hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D-glucose. GO:0004334 fumarylacetoacetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004334 Reactome:R-HSA-71181|EC:3.7.1.2|UM-BBD_reactionID:r0107|MetaCyc:FUMARYLACETOACETASE-RXN|RHEA:10244|KEGG_REACTION:R01364 fumarylacetoacetate hydrolase activity|beta-diketonase activity|4-fumarylacetoacetate fumarylhydrolase activity Catalysis of the reaction: 4-fumarylacetoacetate + H(2)O = acetoacetate + fumarate + H(+). GO:0004333 fumarate hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004333 MetaCyc:FUMHYDR-RXN|RHEA:12460|Reactome:R-HSA-451033|KEGG_REACTION:R01082|EC:4.2.1.2|Reactome:R-HSA-70982 (S)-malate hydro-lyase activity|(S)-malate hydro-lyase (fumarate-forming)|L-malate hydro-lyase activity|fumarase activity Catalysis of the reaction: (S)-malate = fumarate + H(2)O. GO:0004336 galactosylceramidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004336 RHEA:14297|Reactome:R-HSA-1606564|MetaCyc:GALACTOSYLCERAMIDASE-RXN|EC:3.2.1.46 galactocerebrosidase activity|ceramide galactosidase activity|D-galactosyl-N-acylsphingosine galactohydrolase activity|galactocerebroside beta-galactosidase activity|galactocerebroside galactosidase activity|galactocerebroside-beta-D-galactosidase activity|lactosylceramidase I|beta-galactosylceramidase activity|galactosylceramide beta-galactosidase activity|galactosylceramidase I|galcerase activity|cerebroside galactosidase activity|cerebroside beta-galactosidase activity|galactosylcerebrosidase activity|lactosylceramidase activity|beta-galactocerebrosidase activity Catalysis of the reaction: D-galactosyl-N-acylsphingosine + H2O = D-galactose + N-acylsphingosine. GO:0004335 galactokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004335 KEGG_REACTION:R01092|Reactome:R-HSA-70355|Reactome:R-HSA-5610026|MetaCyc:GALACTOKIN-RXN|EC:2.7.1.6|RHEA:13553 ATP:D-galactose 1-phosphotransferase activity|galactokinase (phosphorylating)|ATP:D-galactose-1-phosphotransferase activity Catalysis of the reaction: D-galactose + ATP = alpha-D-galactose 1-phosphate + ADP + 2 H(+). OBO:ddanat#develops_from develops_from biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/ddanat#develops_from develops_from GO:0004330 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004330 GO:0004332 fructose-bisphosphate aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004332 Reactome:R-HSA-71496|Reactome:R-HSA-71495|RHEA:14729|MetaCyc:F16ALDOLASE-RXN|EC:4.1.2.13 aldolase activity|fructose-1,6-bisphosphate triosephosphate-lyase activity|phosphofructoaldolase activity|fructose 1,6-diphosphate aldolase activity|D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase activity|1,6-diphosphofructose aldolase activity|fructoaldolase activity|ketose 1-phosphate aldolase activity|fructose 1-phosphate aldolase activity|fructose 1-monophosphate aldolase activity|D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase (glycerone-phosphate-forming)|zymohexase activity|fructose diphosphate aldolase activity|SMALDO|diphosphofructose aldolase activity Catalysis of the reaction: D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde-3-phosphate. GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004331 Reactome:R-HSA-5628905|RHEA:17289|MetaCyc:3.1.3.46-RXN|Reactome:R-HSA-70262|EC:3.1.3.46 beta-D-fructose-2,6-bisphosphate 2-phosphohydrolase activity|fructose-2,6-bisphosphatase activity|D-fructose-2,6-bisphosphate 2-phosphohydrolase activity Catalysis of the reaction: D-fructose 2,6-bisphosphate + H2O = D-fructose-6-phosphate + phosphate. GO:0018979 trichloroethylene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018979 UM-BBD_pathwayID:tce TCE metabolic process|trichloroethene metabolic process|trichloroethene metabolism|TCE metabolism|trichloroethylene metabolism The chemical reactions and pathways involving trichloroethylene, a toxic, colorless, photoreactive, chlorinated hydrocarbon liquid, commonly used as a metal degreaser and solvent. GO:0018978 anaerobic 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018978 UM-BBD_pathwayID:ddt2 anaerobic DDT metabolism|anaerobic DDT metabolic process|anaerobic 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolism The chemical reactions and pathways involving 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated, broad spectrum, contact insecticide, in the absence of oxygen. GO:0018975 anaerobic 2,4,6-trinitrotoluene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018975 UM-BBD_pathwayID:tnt2 anaerobic 2,4,6-trinitrotoluene metabolism The chemical reactions and pathways involving 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid, that occur in the absence of oxygen. GO:0018974 2,4,6-trinitrotoluene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018974 TNT metabolism|2,4,6-trinitrotoluene metabolism|TNT metabolic process The chemical reactions and pathways involving 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid. It is prepared from toluene treated with concentrated sulfuric and nitric acids and is used in shells, bombs, and blasting explosives. GO:0018977 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018977 UM-BBD_pathwayID:ddt DDT metabolic process|1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolism|DDT metabolism The chemical reactions and pathways involving 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated broad spectrum contact insecticide. GO:0018976 1,2,3-tribromopropane metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018976 UM-BBD_pathwayID:tbp 1,2,3-tribromopropane metabolism The chemical reactions and pathways involving 1,2,3-tribromopropane, a toxic and volatile organic compound commonly used as a nematocide in agriculture. GO:0018971 anaerobic toluene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018971 UM-BBD_pathwayID:tol2 anaerobic toluene metabolism The chemical reactions and pathways involving toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products, that occur in the absence of oxygen. GO:0018970 toluene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018970 methylbenzene metabolic process|toluene metabolism|methylbenzene metabolism The chemical reactions and pathways involving toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products such as gasoline and commonly used as a paint thinning agent and in other solvent applications. GO:0018973 trinitrotoluene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018973 UM-BBD_pathwayID:tnt trinitrotoluene metabolism The chemical reactions and pathways involving trinitrotoluene, a methylated benzene molecule with three NO2 groups attached to it. This includes the explosive TNT, 1-methyl-2,4,6-trinitrobenzene. GO:0018972 toluene-4-sulfonate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018972 MetaCyc:TOLSULFDEG-PWY|UM-BBD_pathwayID:tsa 4-toluenesulfonate metabolism|toluene-4-sulphonate metabolism|4-methylbenzenesulfonate metabolism|4-methylbenzenesulfonate metabolic process|toluene-4-sulphonate metabolic process|toluene-4-sulfonate metabolism|4-toluenesulfonate metabolic process The chemical reactions and pathways involving toluene-4-sulfonate, the anion of 4-toluene sulfonic acid, a white crystalline solid which is highly hygroscopic and soluble in water. PO:0025202 microsporangium biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025202 microsporangia (exact, plural)|macrosporangia (related)|megasporangia (exact, plural)|小胞子嚢 (Japanese, exact)|macrosporangium (related)|microsporangio (Spanish, exact) A sporangium (PO:0025094) in which microspores (PO:0020048) are produced. PO:0025201 megasporangium biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025201 大胞子嚢 (Japanese, exact)|megasporangio (Spanish, exact) A sporangium in which megaspores are produced. GO:0004305 ethanolamine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004305 Reactome:R-HSA-1483222|KEGG_REACTION:R01468|RHEA:13069|MetaCyc:ETHANOLAMINE-KINASE-RXN|EC:2.7.1.82 ATP:ethanolamine O-phosphotransferase activity|ethanolamine phosphokinase activity|ethanolamine kinase (phosphorylating) Catalysis of the reaction: ATP + ethanolamine = ADP + 2 H(+) + phosphoethanolamine. GO:0004304 estrone sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004304 MetaCyc:ESTRONE-SULFOTRANSFERASE-RXN|EC:2.8.2.4|RHEA:15973|Reactome:R-HSA-176664 oestrogen sulphotransferase activity|3'-phosphoadenylyl sulfate-estrone 3-sulfotransferase activity|estrone sulphotransferase activity|estrogen sulphotransferase activity|estrogen sulfotransferase|3'-phosphoadenylylsulfate:oestrone sulfotransferase activity|3'-phosphoadenylyl-sulfate:estrone 3-sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + estrone = adenosine 3',5'-bisphosphate + estrone 3-sulfate. GO:0004307 ethanolaminephosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004307 Reactome:R-HSA-1482962|RHEA:32943|EC:2.7.8.1|MetaCyc:ETHANOLAMINEPHOSPHOTRANSFERASE-RXN phosphorylethanolamine-glyceride transferase activity|CDPethanolamine diglyceride phosphotransferase activity|EPT|CDP-ethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase activity|diacylglycerol ethanolaminephosphotransferase activity Catalysis of the reaction: CDP-ethanolamine + 1,2-diacylglycerol = CMP + a phosphatidylethanolamine. GO:0004306 ethanolamine-phosphate cytidylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004306 MetaCyc:2.7.7.14-RXN|EC:2.7.7.14|RHEA:24592|Reactome:R-HSA-1483190 CTP:phosphoethanolamine cytidylyltransferase activity|ethanolamine phosphate cytidylyltransferase activity|ET|phosphoethanolamine cytidylyltransferase activity|phosphorylethanolamine transferase activity|CTP-phosphoethanolamine cytidylyltransferase activity|CTP:ethanolamine-phosphate cytidylyltransferase activity Catalysis of the reaction: CTP + ethanolamine phosphate = diphosphate + CDP-ethanolamine. GO:0004301 epoxide hydrolase activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0004301 Reactome:R-HSA-9026000|UM-BBD_enzymeID:e0397|Reactome:R-HSA-9026008|Reactome:R-HSA-9020257|Reactome:R-HSA-9018877|Reactome:R-HSA-9025998|EC:3.3.2.10|Reactome:R-HSA-9020258|Reactome:R-HSA-9018862|Reactome:R-HSA-2161961|RHEA:19037|Reactome:R-HSA-9020253|Reactome:R-HSA-9020252|Reactome:R-HSA-9024973|Reactome:R-HSA-9020270|Reactome:R-HSA-9024993|Reactome:R-HSA-9024890|MetaCyc:3.3.2.10-RXN aryl epoxide hydrase activity|soluble epoxide hydrolase activity|sEH|trans-stilbene oxide hydrolase activity|epoxide hydratase activity|arene-oxide hydratase activity|cytosolic epoxide hydrolase activity|epoxide hydrase activity Catalysis of the reaction: an epoxide + H2O = a glycol. GO:0004300 enoyl-CoA hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004300 UM-BBD_enzymeID:e0014|Reactome:R-HSA-70870|EC:4.2.1.17|Reactome:R-HSA-77325|Reactome:R-HSA-77333|Reactome:R-HSA-77344|MetaCyc:ENOYL-COA-HYDRAT-RXN|RHEA:16105|Reactome:R-HSA-77301|Reactome:R-HSA-77314|Reactome:R-HSA-77256|Reactome:R-HSA-70830|Reactome:R-HSA-77277 short-chain enoyl-CoA hydratase activity|D-3-hydroxyacyl-CoA dehydratase|acyl coenzyme A hydrase activity|2-octenoyl coenzyme A hydrase activity|enoyl hydrase activity|enol-CoA hydratase activity|(3S)-3-hydroxyacyl-CoA hydro-lyase activity|enoyl coenzyme A hydratase activity|short chain enoyl coenzyme A hydratase activity|crotonyl hydrase activity|enoyl coenzyme A hydrase (D)|enoyl coenzyme A hydrase (L)|unsaturated acyl-CoA hydratase activity|trans-2-enoyl-CoA hydratase activity|beta-hydroxyacid dehydrase activity|beta-hydroxyacyl-CoA dehydrase activity|ECH|hydratase, enoyl coenzyme A|2-enoyl-CoA hydratase activity Catalysis of the reaction: (3S)-3-hydroxyacyl-CoA = trans-2-enoyl-CoA + H2O. GO:0004303 estradiol 17-beta-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004303 Reactome:R-HSA-804969|Reactome:R-HSA-6810594|Reactome:R-HSA-8862137|EC:1.1.1.62|MetaCyc:ESTRADIOL-17-BETA-DEHYDROGENASE-RXN|Reactome:R-HSA-5693390|Reactome:R-HSA-5696822 17beta-estradiol dehydrogenase activity|17-beta-estradiol dehydrogenase activity|17beta-hydroxysteroid dehydrogenase activity|17-beta-hydroxysteroid dehydrogenase activity|17beta,20alpha-hydroxysteroid dehydrogenase activity|estradiol 17beta-dehydrogenase activity|estrogen 17-oxidoreductase activity|estradiol-17beta:NAD(P)+ 17-oxidoreductase activity|estradiol dehydrogenase activity|17-beta-HSD activity|20alpha-hydroxysteroid dehydrogenase|17beta-HSD Catalysis of the reaction: estradiol-17-beta + NADP+ = estrone + NADPH + H+. GO:0004302 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004302 GO:0018949 m-xylene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018949 UM-BBD_pathwayID:mxy meta-xylene metabolism|meta-xylene metabolic process|m-xylene metabolism The chemical reactions and pathways involving m-xylene, (1,3-dimethylbenzene) a colorless, liquid aromatic hydrocarbon. GO:0018946 aerobic organosilicon metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018946 UM-BBD_pathwayID:osi aerobic organosilicon metabolism|aerobic organosilicone metabolic process|aerobic organosilicone metabolism The chemical reactions and pathways involving organosilicons, organic compounds that contain silicon, in the presence of oxygen. GO:0018945 organosilicon metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018945 UM-BBD_pathwayID:osi organosilicon metabolism|organosilicone metabolic process|organosilicone metabolism The chemical reactions and pathways involving any organosilicon, organic compounds that contain silicon, a nonmetal element analogous to carbon. GO:0018948 xylene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018948 xylene metabolism The chemical reactions and pathways involving xylene, a mixture of three colorless, aromatic hydrocarbon liquids, ortho-, meta- and para-xylene. GO:0018947 anaerobic organosilicon metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018947 UM-BBD_pathwayID:osi anaerobic organosilicon metabolism|anaerobic organosilicone metabolic process|anaerobic organosilicone metabolism The chemical reactions and pathways involving organosilicons, organic compounds that contain silicon, in the absence of oxygen. GO:0018942 organometal metabolic process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0018942 organometal metabolism The chemical reactions and pathways involving organometals, any metal-containing organic compound, especially one in which the metal atom is linked directly to one of more carbon atoms. GO:0018941 organomercury metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018941 UM-BBD_pathwayID:ogm organomercury metabolism The chemical reactions and pathways involving organomercury compound, any organic compound containing a mercury atom. GO:0018944 tri-n-butyltin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018944 UM-BBD_pathwayID:tbt tri-n-butyltin metabolism The chemical reactions and pathways involving tri-n-butyltin, an organometallic compound composed of three butyl chains attached to a tin atom. Tri-n-butyltin is used as an antifouling agent in ship bottom paints and can be toxic to many marine organisms. GO:0018943 organotin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018943 organotin metabolism The chemical reactions and pathways involving organotin, an organic compound containing a tin atom. GO:0018940 orcinol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018940 UM-BBD_pathwayID:orc|MetaCyc:P342-PWY orcin metabolic process|orcinol metabolism|orcin metabolism The chemical reactions and pathways involving orcinol (5-methyl-1,3-benzenediol), an aromatic compound derived from the fermentation of lichen, and synthesized, probably as a fungicide, by some higher plants. GO:0004309 exopolyphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004309 RHEA:21528|MetaCyc:EXOPOLYPHOSPHATASE-RXN|EC:3.6.1.11 acid phosphoanhydride phosphohydrolase activity|Gra-Pase activity|polyphosphate phosphohydrolase activity|exopolypase activity|metaphosphatase activity Catalysis of the reaction: polyphosphate(n) + H2O = polyphosphate(n-1) + phosphate. GO:0004308 exo-alpha-sialidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004308 Reactome:R-HSA-9638120|Reactome:R-HSA-1605723|EC:3.2.1.18|Reactome:R-HSA-1605724|Reactome:R-HSA-168870|Reactome:R-HSA-1605768|Reactome:R-HSA-4084999|Reactome:R-HSA-4341669|MetaCyc:3.2.1.18-RXN|Reactome:R-HSA-4085029|Reactome:R-HSA-4084994 alpha-neuraminidase activity|acetylneuraminidase activity|neuraminidase activity|acetylneuraminyl hydrolase activity|sialidase activity|N-acylneuraminate glycohydrolase activity Catalysis of the hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)-glycosidic linkages of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates. GO:0004316 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004316 MetaCyc:3-OXOACYL-ACP-REDUCT-RXN|RHEA:17397|EC:1.1.1.100|Reactome:R-HSA-8862152 beta-ketoacyl-acyl carrier protein reductase activity|3-oxoacyl-[acyl-carrier protein] reductase activity|beta-ketoacyl-acyl-carrier protein(ACP) reductase activity|3-oxoacyl-ACPreductase activity|beta-ketoacyl thioester reductase activity|(3R)-3-hydroxyacyl-acyl-carrier-protein:NADP+ oxidoreductase activity|3-oxoacyl-acyl-carrier-protein reductase activity|beta-ketoacyl reductase activity|beta-ketoacyl-ACP reductase activity|beta-ketoacyl acyl carrier protein (ACP) reductase activity|3-ketoacyl acyl carrier protein reductase activity|NADPH-specific 3-oxoacyl-acylcarrier proteinreductase activity|3-oxoacyl-ACP reductase activity Catalysis of the reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+. GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004315 MetaCyc:3-OXOACYL-ACP-SYNTH-RXN|RHEA:22836|EC:2.3.1.41 beta-ketoacyl-acyl carrier protein synthase activity|beta-ketoacyl synthetase activity|KASI|3-oxoacyl:ACP synthase I|fatty acid condensing enzyme activity|beta-ketoacyl-acyl-carrier-protein synthase I|condensing enzyme activity|3-oxoacyl-[acyl-carrier protein] synthase activity|ketoacyl-ACP synthase activity|beta-ketoacyl acyl carrier protein synthase activity|beta-ketoacyl-acyl carrier protein synthetase activity|FabB|acyl-acyl-carrier-protein:malonyl-acyl-carrier-protein C-acyltransferase (decarboxylating)|3-oxoacyl-ACP synthase activity|3-oxoacyl-acyl-carrier-protein synthase activity|acyl-malonyl(acyl-carrier-protein)-condensing enzyme activity|acyl-malonyl acyl carrier protein-condensing enzyme activity|beta-ketoacyl-ACP synthase I activity|KAS I activity|FabF1|3-ketoacyl-acyl carrier protein synthase activity|beta-ketoacylsynthase activity|beta-ketoacyl-[acyl carrier protein] synthase activity|beta-ketoacyl-ACP synthetase activity Catalysis of the reaction: acyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxoacyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]. CHEBI:77208 hexadecanedioyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77208 GO:0004318 enoyl-[acyl-carrier-protein] reductase (NADH) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004318 EC:1.3.1.9|MetaCyc:ENOYL-ACP-REDUCT-NADH-RXN NADH-enoyl acyl carrier protein reductase activity|enoyl-acyl-carrier-protein reductase (NADH)|enoyl-ACP reductase (NADH) activity|enoyl-[acyl-carrier protein] reductase (NADH) activity|NADH-specific enoyl-ACP reductase activity|acyl-acyl-carrier-protein:NAD+ oxidoreductase Catalysis of the reaction: acyl-[acyl-carrier protein] + NAD+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH + H+. CHEBI:77207 tetradecanedioyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77207 CHEBI:77206 (13Z,16Z,19Z,22Z,25Z)-octacosapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77206 GO:0004317 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004317 KEGG_REACTION:R04462|RHEA:41908|MetaCyc:4.2.1.61-RXN|EC:4.2.1.59 beta-hydroxypalmitoyl-acyl carrier protein dehydrase activity|D-3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity|3-hydroxypalmitoyl-ACP dehydratase activity|(3R)-3-hydroxypalmitoyl-[acyl-carrier-protein] hydro-lyase activity|beta-hydroxypalmitoyl thioester dehydratase activity|D-3-hydroxypalmitoyl-acyl-carrier-protein dehydratase activity|(3R)-3-hydroxypalmitoyl-acyl-carrier-protein hydro-lyase activity|(3R)-3-hydroxypalmitoyl-acyl-carrier-protein hydro-lyase (hexadec-2-enoyl-acyl-carrier protein-forming)|3-hydroxypalmitoyl-acyl-carrier-protein dehydratase activity|beta-hydroxypalmityl-ACP dehydrase activity|3-hydroxypalmitoyl-[acyl-carrier protein] dehydratase activity Catalysis of the reaction: (3R)-3-hydroxypalmitoyl-[acyl-carrier protein] = 2-hexadecenoyl-[acyl-carrier protein] + H2O. GO:0004312 fatty acid synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004312 Reactome:R-HSA-75872|RHEA:14993|MetaCyc:FATTY-ACID-SYNTHASE-RXN|EC:2.3.1.85 fatty-acid synthase activity|acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing) Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ = long-chain fatty acid + n+1 CoA + n CO2 + 2n NADP+. GO:0004311 farnesyltranstransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004311 RHEA:17653|MetaCyc:FARNESYLTRANSTRANSFERASE-RXN|KEGG_REACTION:R02061|EC:2.5.1.29 geranylgeranyl-PP synthetase activity|trans,trans-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase activity|geranylgeranyl pyrophosphate synthase activity|geranylgeranyl-diphosphate synthase activity|geranylgeranyl pyrophosphate synthetase activity|farnesyltransferase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + isopentenyl diphosphate = diphosphate + geranylgeranyl diphosphate. CHEBI:53259 poly(ethylene terephthalate) macromolecule biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_53259 GO:0004314 [acyl-carrier-protein] S-malonyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004314 MetaCyc:MALONYL-COA-ACP-TRANSACYL-RXN|Reactome:R-HSA-8933547|EC:2.3.1.39 malonyl-CoA:acyl-carrier-protein S-malonyltransferase activity|malonyl coenzyme A-acyl carrier protein transacylase activity|malonyl-CoA:acyl carrier protein transacylase activity|ACP S-malonyltransferase activity|acyl-carrier-protein S-malonyltransferase activity|MCAT activity|malonyl-CoA-acyl carrier protein transacylase activity|acyl carrier protein malonyltransferase activity|acyl carrier proteinmalonyltransferase activity|malonyl-CoA:AcpM transacylase activity|MAT|[acyl-carrier protein] S-malonyltransferase activity|malonyl-CoA:ACP transacylase activity|malonyl transacylase activity|FabD|malonyl transferase activity Catalysis of the reaction: malonyl-CoA + [acyl-carrier protein] = CoA + malonyl-[acyl-carrier protein]. GO:0004313 [acyl-carrier-protein] S-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004313 MetaCyc:ACP-S-ACETYLTRANSFER-RXN|EC:2.3.1.38|RHEA:41788 acyl-carrier-protein acetyltransferase activity|ACAT activity|acetyl coenzyme A-acyl-carrier-protein transacylase activity|acyl-carrier-protein S-acetyltransferase activity|[acyl-carrier protein] S-acetyltransferase activity|acetyl-CoA:acyl-carrier-protein S-acetyltransferase activity|acyl-carrier-proteinacetyltransferase activity|ACP S-acetyltransferase activity|ACP acetyltransferase activity|ACPacetyltransferase activity Catalysis of the reaction: acetyl-CoA + [acyl-carrier protein] = CoA + acetyl-[acyl-carrier protein]. GO:0004310 farnesyl-diphosphate farnesyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004310 Reactome:R-HSA-191402|Reactome:R-HSA-191405|MetaCyc:2.5.1.21-RXN|EC:2.5.1.21 farnesyl-diphosphate:farnesyl-diphosphate farnesyltransferase activity|presqualene-diphosphate synthase activity|presqualene synthase activity Catalysis of the reaction: 2 farnesyl diphosphate = diphosphate + presqualene diphosphate. GO:0102900 dehydroabietadienal hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102900 MetaCyc:RXN-8534 Catalysis of the reaction: dehydroabietadienal + NADPH + O2 <=> dehydroabietic acid + NADP + H2O. GO:0102902 isopimaradienal hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102902 MetaCyc:RXN-8538 Catalysis of the reaction: isopimaradienal + NADPH + O2 <=> isopimaric acid + NADP + H2O. GO:0018957 phenanthrene catabolic process via trans-9(S),10(S)-dihydrodiolphenanthrene biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018957 UM-BBD_pathwayID:pha2 phenanthrene breakdown via trans-9(S),10(S)-dihydrodiolphenanthrene|phenanthrene degradation via trans-9(S),10(S)-dihydrodiolphenanthrene The chemical reactions and pathways resulting in the breakdown of phenanthrene, a tricyclic aromatic hydrocarbon, where trans-9(S),10(S)-dihydrodiolphenanthrene is the principal intermediate metabolite. GO:0102901 isopimaradienol hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102901 MetaCyc:RXN-8536 Catalysis of the reaction: H+ + isopimaradienol + NADPH + O2 <=> isopimaradiene-diol + NADP + H2O. GO:0018956 phenanthrene catabolic process via trans-9(R),10(R)-dihydrodiolphenanthrene biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018956 UM-BBD_pathwayID:pha3 phenanthrene breakdown via trans-9(R),10(R)-dihydrodiolphenanthrene|phenanthrene degradation via trans-9(R),10(R)-dihydrodiolphenanthrene The chemical reactions and pathways resulting in the breakdown of phenanthrene, a tricyclic aromatic hydrocarbon, where trans-9(R),10(R)-dihydrodiolphenanthrene is the principal intermediate metabolite. GO:0018959 aerobic phenol-containing compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018959 UM-BBD_pathwayID:pba aerobic phenol-containing compound metabolism The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen. GO:0102904 germacrene C synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102904 MetaCyc:RXN-8561|RHEA:28302|EC:4.2.3.60 Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = germacrene C + diphosphoric acid. GO:0102903 gamma-terpinene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102903 RHEA:32559|EC:4.2.3.114|MetaCyc:RXN-8547 Catalysis of the reaction: geranyl diphosphate = gamma-terpinene + diphosphoric acid. GO:0018958 phenol-containing compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018958 UM-BBD_pathwayID:phe carbolic acid metabolic process|phenol-containing compound metabolism|carbolic acid metabolism|hydroxybenzene metabolism|hydroxybenzene metabolic process The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring. GO:0018953 p-cymene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018953 UM-BBD_pathwayID:pcy p-cymene metabolism The chemical reactions and pathways involving p-cymene, 1-methyl-4-isopropylbenzene, one of the alkyl-substituted aromatic hydrocarbons found in volatile oils from over 100 plants. GO:0102906 7-epi-alpha-selinene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102906 EC:4.2.3.86|RHEA:30383|MetaCyc:RXN-8609 Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> (-)-7-epi-alpha-selinene + diphosphoric acid. GO:0018952 parathion metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018952 UM-BBD_pathwayID:pthn parathion metabolism The chemical reactions and pathways involving parathion, a highly toxic organophosphate compound formerly used as a broad spectrum insecticide, acaricide, fumigant and nematocide. Degradation of parathion by sunlight or liver enzymes can result in the formation of the active compound paraoxon which interferes with the nervous system through cholinesterase inhibition. GO:0102905 valencene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102905 EC:4.2.3.73|RHEA:29511|MetaCyc:RXN-8608 Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> (+)-valencene + diphosphoric acid. GO:0018955 phenanthrene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018955 UM-BBD_pathwayID:pha phenanthrene metabolism The chemical reactions and pathways involving phenanthrene, a tricyclic aromatic hydrocarbon used in explosives and in the synthesis of dyes and drugs. Although phenanthrene is not mutagenic or carcinogenic, it has been shown to be toxic to marine diatoms, gastropods, mussels, crustaceans, and fish. GO:0102908 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0102908 GO:0102907 sesquisabinene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102907 MetaCyc:RXN-8622 Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> diphosphoric acid + sesquisabinene. GO:0018954 pentaerythritol tetranitrate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018954 UM-BBD_pathwayID:petn pentaerythritol tetranitrate metabolism The chemical reactions and pathways involving pentaerythritol tetranitrate, C(CH2-O-NO2)4, a substance produced for use as an explosive and a vasodilator. CHEBI:77201 (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77201 GO:0102909 alpha-ketoglutarate reductase activity (NADH-dependent) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102909 MetaCyc:RXN-8645 Catalysis of the reaction: NAD + 2-hydroxyglutarate = H+ + 2-oxoglutarate + NADH. CHEBI:77200 (10E,12Z)-octadecadienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77200 GO:0018951 p-xylene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018951 UM-BBD_pathwayID:pxy p-xylene metabolism|para-xylene metabolism|para-xylene metabolic process The chemical reactions and pathways involving p-xylene, (1,4-dimethylbenzene) a colorless, liquid aromatic hydrocarbon. GO:0018950 o-xylene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018950 UM-BBD_pathwayID:oxy o-xylene metabolism|ortho-xylene metabolic process|ortho-xylene metabolism The chemical reactions and pathways involving o-xylene, (1,2-dimethylbenzene) a colorless, liquid aromatic hydrocarbon. CHEBI:77205 (8Z,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77205 GO:0004319 enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004319 MetaCyc:ENOYL-ACP-REDUCT-NADPH-RXN|EC:1.3.1.10 acyl-acyl-carrier-protein:NADP+ oxidoreductase (B-specific)|NADPH 2-enoyl Co A reductase activity|enoyl-[acyl-carrier protein] reductase (NADPH, B-specific) activity|enoyl-ACP reductase (NADPH, B-specific) activity|enoyl-acyl-carrier-protein reductase (NADPH2, B-specific)|enoyl-acyl-carrier-protein reductase (NADPH, B-specific)|reductase, enoyl-acyl carrier protein (reduced nicotinamide adenine dinucleotide phosphate)|enoyl acyl-carrier-protein reductase activity Catalysis of the reaction: acyl-[acyl-carrier protein] + NADP+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NADPH + H+. CHEBI:77203 (11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77203 CHEBI:77202 (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77202 GO:0102751 UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102751 RHEA:56560|EC:2.4.1.186|MetaCyc:RXN-7667 Catalysis of the reaction: UDP-alpha-D-glucose + a glucosyl-glycogenin = (1,4-alpha-D-glucosyl)n-glucosyl glucogenin + UDP + H+. GO:0102750 tetrahydrogeranylgeranyl-chlorophyll a reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102750 MetaCyc:RXN-7666 Catalysis of the reaction: chlorophyll a + NADP = tetrahydrogeranylgeranyl-chlorophyll a + NADPH + H+. GO:0102753 chlorophyllide b:geranyl-geranyl diphosphate geranyl-geranyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102753 MetaCyc:RXN-7673 Catalysis of the reaction: H+ + chlorophyllide b(1-) + 2-trans,6-trans,10-trans-geranylgeranyl diphosphate <=> geranylgeranyl-chlorophyll b + diphosphoric acid. GO:0102752 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102752 MetaCyc:RXN-7669|EC:2.4.1.18 Catalysis of the reaction: a glucosylated glycogenin = a glycogen. GO:0102755 gibberellin-15(closed lactone form),2-oxoglutarate:oxygen oxidoreductase (3beta-hydroxylating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102755 MetaCyc:RXN-7680 Catalysis of the reaction: gibberellin A15 (closed lactone form) + O2 + 2-oxoglutarate = gibberellin A37 (closed lactone form) + succinate + carbon dioxide. GO:0102754 chlorophyllide-b:phytyl-diphosphate phytyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102754 MetaCyc:RXN-7674 Catalysis of the reaction: H+ + chlorophyllide b + (E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate <=> chlorophyll b + diphosphoric acid. GO:0102757 NADPH phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102757 MetaCyc:RXN-7703|RHEA:60664 Catalysis of the reaction: NADPH + H2O = NADH + hydrogenphosphate. GO:0102756 very-long-chain 3-ketoacyl-CoA synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102756 EC:2.3.1.199|RHEA:32727|MetaCyc:RXN-7697 Catalysis of the reaction: malonyl-CoA + a very-long-chain 2,3,4-saturated fatty acyl CoA = carbon dioxide + coenzyme A + a very-long-chain oxoacyl-CoA. GO:0102759 campestanol hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102759 MetaCyc:RXN-773 Catalysis of the reaction: H+ + campestanol + O2 + NADPH <=> 6-deoxycathasterone + H2O + NADP. GO:0102758 very-long-chain enoyl-CoA reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102758 EC:1.3.1.93|RHEA:14473|MetaCyc:RXN-7711 Catalysis of the reaction: NADP(3-) + a very-long-chain 2,3,4-saturated fatty acyl CoA <=> NADPH(4-) + H+ + a very-long-chain trans-2,3-dehydroacyl-CoA. GO:0102760 6-deoxocathasterone hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102760 MetaCyc:RXN-774 Catalysis of the reaction: 6-deoxycathasterone + O2 + a reduced electron acceptor <=> 6-deoxoteasterone + H2O + an oxidized electron acceptor. GO:0102762 eriodictyol 4'-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102762 MetaCyc:RXN-7754 Catalysis of the reaction: eriodictyol + S-adenosyl-L-methionine <=> H+ + hesperetin(1-) + S-adenosyl-L-homocysteine. GO:0102761 eriodictyol 3'-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102761 RHEA:60948|MetaCyc:RXN-7753 Catalysis of the reaction: eriodictyol + S-adenosyl-L-methionine <=> H+ + homoeriodictyol + S-adenosyl-L-homocysteine. GO:0102764 6-deoxotyphasterol C-23 hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102764 MetaCyc:RXN-777 Catalysis of the reaction: 6-deoxotyphasterol + O2 + a reduced electron acceptor = 6-deoxocastasterone + H2O + an oxidized electron acceptor. GO:0102763 phytyl-P kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102763 MetaCyc:RXN-7763|RHEA:38099 Catalysis of the reaction: phytyl phosphate(2-) + a nucleoside triphosphate <=> (E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate + a nucleoside diphosphate. GO:0102766 naringenin 7-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102766 RHEA:31539|MetaCyc:RXN-7773|EC:2.1.1.232 Catalysis of the reaction: (S)-naringenin(1-) + S-adenosyl-L-methionine <=> sakuranetin + S-adenosyl-L-homocysteine + H+. GO:0102765 UDP-D-apiose synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102765 MetaCyc:RXN-7770 Catalysis of the reaction: H+ + UDP-alpha-D-glucuronate = UDP-alpha-D-apiose + carbon dioxide. GO:0102768 anthocyanidin synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102768 MetaCyc:RXN-7785 Catalysis of the reaction: flavan-3,3',4,4',5,5',7-heptol + O2 + 2-oxoglutarate = H+ + delphinidin + 2 H2O + carbon dioxide + succinate. GO:0102767 flavanone 4'-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102767 EC:2.1.1.231|MetaCyc:RXN-7777|RHEA:31743 Catalysis of the reaction: (S)-naringenin + S-adenosyl-L-methionine = 2 H+ + ponciretin + S-adenosyl-L-homocysteine. GO:0102769 dihydroceramide glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102769 MetaCyc:RXN-7793|EC:2.4.1.80 Catalysis of the reaction: UDP-alpha-D-glucose + a dihydroceramide = UDP + H+ + a D-glucosyl-N-acylsphinganine. CHEBI:7872 oxytocin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_7872 GO:0102771 sphingolipid very long chain fatty acid alpha-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102771 MetaCyc:RXN-7796|RHEA:46512 Catalysis of the reaction: O2 + NADPH + H+ + a dihydroceramide = NADP + H2O + an alpha hydroxydihydroceramide. GO:0102770 inositol phosphorylceramide synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102770 MetaCyc:RXN-7795 Catalysis of the reaction: an L-1-phosphatidyl-inositol + a dihydroceramide = an inositol phosphodihydroceramide + a 1,2-diacyl-sn-glycerol. GO:0102773 dihydroceramide kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102773 EC:2.7.1.138|MetaCyc:RXN-7799 Catalysis of the reaction: ATP + a dihydroceramide = ADP + H+ + a dihydroceramide 1-phosphate. GO:0102772 sphingolipid long-chain base 4-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102772 MetaCyc:RXN-7797 Catalysis of the reaction: O2 + H+ + a dihydroceramide + NAD(P)H = H2O + a phytoceramide + NAD(P). GO:0102775 6-(4-methyl-2-oxopentyl)-4-hydroxy-2-pyrone synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102775 MetaCyc:RXN-7826 Catalysis of the reaction: 2 H+ + isovaleryl-CoA + 3 malonyl-CoA = 6-(4-methyl-2-oxopentyl)-4-hydroxy-2-pyrone + 4 coenzyme A + 3 carbon dioxide. GO:0102774 p-coumaroyltriacetic acid lactone synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102774 MetaCyc:RXN-7822 Catalysis of the reaction: 2 H+ + 4-coumaryl-CoA + 3 malonyl-CoA( <=> p-coumaroyltriacetic acid lactone + 4 coenzyme A + 3 carbon dioxide. GO:0102777 caffeoyl-CoA:pelargonidin-3,5-diglucoside 5-O-glucoside-6-O-hydroxycinnamoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102777 EC:2.3.1.153|MetaCyc:RXN-7842 Catalysis of the reaction: anthocyanidin 3,5-di-O-beta-D-glucoside + caffeoyl-CoA <=> pelargonidin-3,5-diglucoside-5-O-caffeoylglucoside + coenzyme A(4-). GO:0102776 UDP-D-glucose:pelargonidin-3-O-beta-D-glucoside 5-O-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102776 MetaCyc:RXN-7828 Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + UDP-alpha-D-glucose <=> anthocyanidin 3,5-di-O-beta-D-glucoside + UDP + H+. GO:0102779 cannabidiolate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102779 RHEA:34411|EC:1.21.3.8|MetaCyc:RXN-7855 Catalysis of the reaction: cannabigerolate + O2 <=> cannabidiolate + hydrogen peroxide. GO:0102778 Delta9-tetrahydrocannabinolate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102778 RHEA:34143|EC:1.21.3.7|MetaCyc:RXN-7854 Catalysis of the reaction: cannabigerolate + O2 <=> Delta(9)-tetrahydrocannabinolic acid + hydrogen peroxide. GO:0102780 sitosterol hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102780 MetaCyc:RXN-7876 Catalysis of the reaction: H+ + sitosterol + O2 + NADPH <=> (22alpha)-hydroxy-sitosterol + H2O + NADP. GO:0102782 cholestanol hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102782 MetaCyc:RXN-7878 Catalysis of the reaction: H+ + epidihydrocholesterin + O2 + NADPH = (22alpha)-hydroxy-cholestanol + H2O + NADP. GO:0102781 isofucosterol hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102781 MetaCyc:RXN-7877 Catalysis of the reaction: H+ + isofucosterol + O2 + NADPH <=> (22alpha)-hydroxy-isofucosterol + H2O + NADP. GO:0102784 lutein oxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102784 MetaCyc:RXN-7884 Catalysis of the reaction: lutein + 2 O2 = 3-hydroxy-beta-ionone + 3-hydroxy-alpha-ionone + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial. GO:0102783 beta-carotene oxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102783 MetaCyc:RXN-7883 Catalysis of the reaction: beta-carotene + 2 O2 = 2 beta-ionone + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial. GO:0102786 stearoyl-[acp] desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102786 RHEA:11776|EC:1.14.19.2|MetaCyc:RXN-7903 Catalysis of the reaction: O2 + a stearoyl-[acp] + a reduced ferredoxin = 2 H2O + an oleoyl-[acp] + an oxidized ferredoxin. GO:0102785 violaxanthin oxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102785 MetaCyc:RXN-7886 Catalysis of the reaction: violaxanthin + 2 O2 = 2 5,6-epoxy-3-hydroxy-9-apo-beta-caroten-9-one + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial. GO:0102788 4-coumaroyl-CoA:pelargonidin-3-O-beta-D-glucoside-6''-O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102788 MetaCyc:RXN-7998 Catalysis of the reaction: 4-coumaryl-CoA + pelargonidin 3-O-beta-D-glucoside = pelargonidin 3-O-beta-D-p-coumaroylglucoside + coenzyme A. GO:0102787 caffeoyl-CoA:pelargonidin-3-O-beta-D-glucoside-6''-O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102787 MetaCyc:RXN-7997 Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + caffeoyl-CoA = pelargonidin 3-O-beta-D-caffeoylglucoside + coenzyme A. GO:0102789 UDP-D-glucose:cyanidin 5-O-beta-D-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102789 MetaCyc:RXN-8005 Catalysis of the reaction: UDP-alpha-D-glucose + cyanidin = H+ + cyanidin 5-O-beta-D-glucoside + UDP. GO:0102711 gibberellin A25,oxoglutarate:oxygen oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102711 MetaCyc:RXN-6541 Catalysis of the reaction: gibberellin A25 + 2-oxoglutarate + O2 <=> gibberellin A13 + succinate + carbon dioxide. GO:0102710 D-inositol-3-phosphate glycosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102710 RHEA:26188|EC:2.4.1.250|MetaCyc:RXN-6501 Catalysis of the reaction: UDP-N-acetyl-alpha-D-glucosamine + 1D-myo-inositol 3-phosphate = 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside 3-phosphate + UDP + H+. GO:0102713 gibberellin A25 hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102713 MetaCyc:RXN-6543 Catalysis of the reaction: gibberellin A25 + 2-oxoglutarate(2-) + O2 <=> gibberellin A46 + succinate(2-) + carbon dioxide. GO:0102712 gibberellin A13,oxoglutarate:oxygen oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102712 MetaCyc:RXN-6542 Catalysis of the reaction: gibberellin A13 + 2-oxoglutarate + O2 <=> gibberellin A43 + succinate + carbon dioxide. GO:0102715 gibberellin A17,oxoglutarate:oxygen oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102715 MetaCyc:RXN-6546 Catalysis of the reaction: gibberellin A17 + 2-oxoglutarate + O2 <=> gibberellin A28 + succinate + carbon dioxide. GO:0102714 gibberellin A12,oxoglutarate:oxygen oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102714 MetaCyc:RXN-6544 Catalysis of the reaction: gibberellin A12 + 2-oxoglutarate + O2 <=> gibberellin A14 + succinate + carbon dioxide. GO:0102717 DIBOA-glucoside oxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102717 MetaCyc:RXN-6685|RHEA:32115|EC:1.14.11.59 Catalysis of the reaction: DIBOA-beta-D-glucoside + O2 + 2-oxoglutarate <=> TRIBOA-beta-D-glucoside + succinate + carbon dioxide. GO:0102716 gibberellin A28,oxoglutarate:oxygen oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102716 MetaCyc:RXN-6547 Catalysis of the reaction: gibberellin A28 + 2-oxoglutarate + O2 <=> (2betaOH)-gibberellin28 + succinate + carbon dioxide. GO:0102719 S-adenosyl-L-methionine:eugenol-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102719 MetaCyc:RXN-6741|EC:2.1.1.146 Catalysis of the reaction: eugenol + S-adenosyl-L-methionine = H+ + O-methyleugenol + S-adenosyl-L-homocysteine. GO:0102718 TRIBOA-glucoside methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102718 MetaCyc:RXN-6687|RHEA:32099|EC:2.1.1.241 Catalysis of the reaction: TRIBOA-beta-D-glucoside + S-adenosyl-L-methionine <=> (2R)-DIMBOA glucoside + S-adenosyl-L-homocysteine + H+. GO:0102720 acetyl-coenzyme A:acetyl alcohol acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102720 MetaCyc:RXN-6762|RHEA:36147|EC:2.3.1.224 Catalysis of the reaction: benzyl alcohol + acetyl-CoA = benzyl acetate + coenzyme A. GO:0102722 gamma-hydroxybutyrate dehydrogenase activity (NAD(P)-dependent biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102722 MetaCyc:RXN-6903 Catalysis of the reaction: 4-hydroxybutyrate + NAD(P) = 4-oxobutanoate + H+ + NAD(P)H. GO:0102721 ubiquinol:oxygen oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102721 MetaCyc:RXN-6883|EC:1.10.3.11|RHEA:30255 Catalysis of the reaction: O2 + 2 an ubiquinol = 2 H2O + 2 an ubiquinone. GO:0102724 UDP-glucose:curcumin monoglucoside glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102724 MetaCyc:RXN-7063 Catalysis of the reaction: UDP-alpha-D-glucose + curcumin monoglucoside = H+ + curcumin diglucoside + UDP. GO:0102723 UDP-glucose:curcumin glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102723 MetaCyc:RXN-7062 Catalysis of the reaction: UDP-alpha-D-glucose + curcumin = curcumin monoglucoside + UDP + H+. GO:0102726 DIMBOA glucoside beta-D-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102726 EC:3.2.1.182|RHEA:33975|MetaCyc:RXN-7082 Catalysis of the reaction: (2R)-DIMBOA glucoside + H2O = H+ + DIMBOA + beta-D-glucose. GO:0102725 24-methyldesmosterol reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102725 MetaCyc:RXN-708 Catalysis of the reaction: H+ + 24-methyldesmosterol + NADPH = campesterol + NADP. GO:0102728 campest-4-en-3-one,NADPH:steroid 5alpha-reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102728 MetaCyc:RXN-711|RHEA:54416 Catalysis of the reaction: (5alpha)-campestan-3-one + NADP = H+ + campest-4-en-3-one + NADPH. GO:0102727 3beta-hydroxysteroid dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102727 MetaCyc:RXN-710 Catalysis of the reaction: campest-4-en-3beta-ol + NAD = campest-4-en-3-one + NADH + H+. GO:0102729 6-oxocampestanol hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102729 MetaCyc:RXN-715 Catalysis of the reaction: H+ + 6-oxocampestanol + O2 + NADPH = cathasterone + H2O + NADP. GO:0102731 D-myo-inositol (1,3,4,6)-tetrakisphosphate 2-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102731 MetaCyc:RXN-7185 Catalysis of the reaction: myo-inositol 1,3,4,6-tetrakisphosphate(8-) + ATP = H+ + 1L-myo-inositol 1,2,3,4,6-pentakisphosphate(10-) + ADP. GO:0102730 cathasterone hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102730 MetaCyc:RXN-716 Catalysis of the reaction: cathasterone + O2 + a reduced electron acceptor <=> teasterone + H2O + an oxidized electron acceptor. GO:0102733 typhasterol C-23 hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102733 MetaCyc:RXN-719 Catalysis of the reaction: typhasterol + O2 + a reduced electron acceptor = castasterone + H2O + an oxidized electron acceptor. GO:0102732 myo-inositol-1,2,3,4,6-heptakisphosphate 5-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102732 MetaCyc:RXN-7186|EC:2.7.1.140 Catalysis of the reaction: 1L-myo-inositol 1,2,3,4,6-pentakisphosphate(10-) + ATP = H+ + myo-inositol hexakisphosphate(12-) + ADP. GO:0102735 trihydroxybenzophenone synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102735 MetaCyc:RXN-7481|RHEA:35143|EC:2.3.1.220 Catalysis of the reaction: benzoyl-CoA + 3 malonyl-CoA + 3 H+ = 2,4,6-trihydroxybenzophenone + 4 coenzyme A + 3 carbon dioxide. GO:0102734 brassinolide synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102734 MetaCyc:RXN-720 Catalysis of the reaction: H+ + castasterone + NADPH + O2 <=> brassinolide + NADP + H2O. GO:0102737 p-coumaroyltriacetic acid synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102737 MetaCyc:RXN-7577 Catalysis of the reaction: 2 H+ + 4-coumaryl-CoA + H2O + 3 malonyl-CoA <=> 4 coenzyme A + 3 carbon dioxide + p-coumaroyltriacetate. GO:0102739 (gibberellin-36), 2-oxoglutarate:oxygen oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102739 MetaCyc:RXN-7591 Catalysis of the reaction: gibberellin A36 + O2 + 2-oxoglutarate <=> H+ + gibberellin A4 + succinate + 2 carbon dioxide. GO:0102738 (gibberellin-14), 2-oxoglutarate:oxygen oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102738 MetaCyc:RXN-7589 Catalysis of the reaction: gibberellin A14 + O2 + 2-oxoglutarate <=> gibberellin A37 + carbon dioxide + succinate. GO:0102740 theobromine:S-adenosyl-L-methionine 1-N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102740 EC:2.1.1.160|MetaCyc:RXN-7599|RHEA:20944 Catalysis of the reaction: theobromine + S-adenosyl-L-methionine <=> H+ + caffeine + S-adenosyl-L-homocysteine. GO:0102742 R(+)-3,4-dihydroxyphenyllactate:NADP+ oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102742 MetaCyc:RXN-7632|EC:1.1.1.237 Catalysis of the reaction: H+ + 3,4-dihydroxyphenylpyruvate + NADPH <=> (2R)-3-(3,4-dihydroxyphenyl)lactate + NADP. GO:0102741 paraxanthine:S-adenosyl-L-methionine 3-N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102741 EC:2.1.1.160|MetaCyc:RXN-7601|RHEA:10280 Catalysis of the reaction: 1,7-dimethylxanthine + S-adenosyl-L-methionine <=> H+ + caffeine + S-adenosyl-L-homocysteine. GO:0102744 all-trans-geranyl-geranyl diphosphate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102744 MetaCyc:RXN-7658 Catalysis of the reaction: H+ + 2-trans,6-trans,10-trans-geranylgeranyl diphosphate + NADPH = dihydrogeranylgeranyl-PP + NADP. GO:0102743 eriodictyol,NADPH:oxygen oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102743 MetaCyc:RXN-7653 Catalysis of the reaction: H+ + eriodictyol + NADPH + O2 <=> 2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxo-4H-chromen-7-olate luteolin-7-olate(1-) + NADP + 2 H2O. GO:0102746 tetrahydrogeranylgeranyl-PP reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102746 MetaCyc:RXN-7660 Catalysis of the reaction: H+ + tetrahydrogeranylgeranyl-PP + NADPH = (E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate + NADP. GO:0102745 dihydrogeranylgeranyl-PP reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102745 MetaCyc:RXN-7659 Catalysis of the reaction: H+ + dihydrogeranylgeranyl-PP + NADPH = tetrahydrogeranylgeranyl-PP + NADP. GO:0102748 geranylgeranyl-chlorophyll a reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102748 MetaCyc:RXN-7664 Catalysis of the reaction: H+ + geranylgeranyl-chlorophyll a + NADPH = dihydrogeranylgeranyl-chlorophyll a + NADP. GO:0102747 chlorophyllide-a:geranyl-geranyl diphosphate geranyl-geranyl transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102747 MetaCyc:RXN-7663 Catalysis of the reaction: H+ + chlorophyllide a(1-) + 2-trans,6-trans,10-trans-geranylgeranyl diphosphate(3-) <=> geranylgeranyl-chlorophyll a + diphosphoric acid. GO:0102749 dihydrogeranylgeranyl-chlorophyll a reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102749 MetaCyc:RXN-7665 Catalysis of the reaction: H+ + dihydrogeranylgeranyl-chlorophyll a + NADPH = tetrahydrogeranylgeranyl-chlorophyll a + NADP. CHEBI:7896 hexadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_7896 CHEBI:28209 5(S)-HETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28209 CHEBI:28205 phaseic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28205 CHEBI:28207 D-galactosamine 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28207 CHEBI:28206 2'-hydroxyisoflavones biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28206 CHEBI:28201 rotenone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28201 CHEBI:28200 2-chloroethanol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28200 CHEBI:28203 N-acetyl-D-phenylalanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28203 UBERON:0006289 rib pre-cartilage condensation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006289 A rib endochondral element that is composed primarily of a pre-cartilage condensation. UBERON:0006288 rib cartilage element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006288 A rib endochondral element that is composed primarily of cartilage tissue. CHEBI:77170 (2E)-tetradecenedioyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77170 CHEBI:100 (-)-medicarpin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_100 UBERON:0006284 early prosencephalic vesicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006284 prosencephalic ventricle|forebrain vesicle|preevaginated forebrain vesicle|prosencephalic vesicle|forebrain ventricle future brain vesicle that gives rise to telencephalic ventricle/lateral ventricles and 3rd ventricle UBERON:0006283 future cardiac ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006283 early heart ventricle|future heart ventricle|primitive ventricle|embryonic heart ventricle|primordial ventricle|presumptive cardiac ventricle heart tube|primitive ventricle of heart|primordial cardiac ventricle|embryonic ventricle Multi-tissue structure that is part of the heart tube and will become the cardiac ventricle. CHEBI:77172 3-oxotetradecanedioyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77172 CHEBI:77179 4-O-methylrhodomycin D biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77179 CHEBI:77178 histological dye biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77178 CHEBI:28217 acrylonitrile biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28217 CHEBI:28211 gibberellin A44 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28211 CHEBI:119 D-synephrine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_119 CHEBI:28214 undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-D-glutaminyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28214 CHEBI:77182 food colouring biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77182 CHEBI:77181 crystal violet cation biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77181 UBERON:0006274 tetrapod parietal bone primordium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006274 parietal bone primordium CHEBI:77186 1-palmityl-2-arachidonoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77186 CHEBI:77185 1-palmityl-2-oleoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77185 UBERON:0006273 otic pit biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006273 otic cup the pair of depressions of thickened otic placode epithelium, that further develops into the otic vesicles CHEBI:77184 1-palmityl-2-arachidonoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77184 UBERON:0006271 orbital fissure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006271 Either of two openings transmitting nerves and blood vessels to or from the orbit. CHEBI:77183 (2E)-hexadecenedioyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77183 CHEBI:77189 (3R)-hydroxyhexadecanedioyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77189 CHEBI:77187 1-palmityl-2-oleoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77187 UBERON:0006279 pleuroperitoneal canal biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006279 pleuroperitoneal channel Each of the canals that links the peritoneal cavity and the caudal part of a pleural cavity. CHEBI:129 (-)-beta-phellandrene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_129 UBERON:0006267 notochordal plate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006267 The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord. CHEBI:122 (-)-usnic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_122 CHEBI:77191 3-oxohexadecanedioyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77191 CHEBI:77190 CDP-dipalmitoyl-sn-glycerol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77190 UBERON:0006264 mouth-foregut junction biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006264 An anatomical junctions that overlaps the mouth and foregut. CHEBI:128 (S)-(-)-alpha-terpineol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_128 CHEBI:77195 10-carboxy-13-deoxydaunorubicin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77195 UBERON:0006261 male genital tubercle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006261 genital tubercle of male|penis anlage A differentiated genital tubercle that is part of a male reproductive system. UBERON:0006260 lingual swellings biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006260 lingual swelling CHEBI:77194 EC 2.7.1.33 (pantothenate kinase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77194 CHEBI:77199 (3S)-hydroxyhexadecanedioyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77199 CHEBI:77198 6-sulfo-D-quinovose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77198 UBERON:0006268 notochordal process biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006268 chordamesoderm|presumptive notochord A midline cellular cord formed from the migration of mesenchymal cells from the primitive knot UBERON:0006256 knee joint primordium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006256 CHEBI:18887 cyclohexa-3,5-diene-1,2-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18887 GO:0102791 sulfuretin synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102791 EC:1.21.3.6|MetaCyc:RXN-8008 Catalysis of the reaction: butein 4'-beta-D-glucoside + O2 + 2 H+ = sulfuretin 6-glucoside + 2 H2O. GO:0102790 cyanidin 5,3-O-glycosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102790 MetaCyc:RXN-8006 Catalysis of the reaction: cyanidin 5-O-beta-D-glucoside + UDP-alpha-D-glucose = cyanin betaine + UDP. GO:0102793 soyasapogenol B glucuronosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102793 EC:2.4.1.262|MetaCyc:RXN-8086|RHEA:31475 Catalysis of the reaction: UDP-alpha-D-glucuronate + soyasapogenol B <=> H+ + UDP + soyasapogenol B 3-O-beta-glucuronate. GO:0102792 sinapaldehyde:NAD(P)+ oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102792 MetaCyc:RXN-8014 Catalysis of the reaction: sinapoyl aldehyde + NADP + H2O <=> 2 H+ + trans-sinapate + NADPH. GO:0102795 1-naphthaldehyde:oxygen oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102795 MetaCyc:RXN-8090|EC:1.2.3.9 Catalysis of the reaction: 1-naphthaldehyde + O2 + H2O = H+ + 1-naphthoate + hydrogen peroxide. GO:0102794 cinnamaldehyde:oxygen oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102794 MetaCyc:RXN-8089|EC:1.2.3.9 Catalysis of the reaction: cinnamaldehyde + O2 + H2O = H+ + trans-cinnamate + hydrogen peroxide. GO:0102797 geranial:oxygen oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102797 MetaCyc:RXN-8093|EC:1.2.3.1 Catalysis of the reaction: geranial + O2 + H2O = H+ + geranate + hydrogen peroxide. GO:0102796 protocatechualdehyde:oxygen oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102796 EC:1.2.3.9|MetaCyc:RXN-8091 Catalysis of the reaction: 3,4-dihydroxybenzaldehyde + O2 + H2O <=> H+ + 3,4-dihydroxybenzoate + hydrogen peroxide. GO:0102799 glucosinolate glucohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102799 EC:3.2.1.147|MetaCyc:RXN-8134 Catalysis of the reaction: H2O + a glucosinolate = alpha-D-glucose + a thiohydroximate-O-sulfate. Glucosinolates are a subclass of thioglucosides. GO:0102798 heptaldehyde:oxygen oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102798 MetaCyc:RXN-8094|EC:1.2.3.1 Catalysis of the reaction: heptanal + O2 + H2O = H+ + heptanoate + hydrogen peroxide. CHEBI:149 (-)-dihydrocarveol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_149 CHEBI:155 (-)-isodihydrocarvone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_155 CHEBI:154 (+)-dihydrocarvone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_154 CHEBI:18822 (Z,Z,Z)-geranylgeraniol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18822 CHEBI:158 (-)-neodihydrocarveol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_158 CHEBI:153 (-)-neoisodihydrocarveol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_153 CHEBI:152 (+)-neodihydrocarveol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_152 CHEBI:151 D-threo-isocitric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_151 CHEBI:150 (-)-isodihydrocarveol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_150 CHEBI:168 (-)-dihydrocarvone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_168 CHEBI:18859 1,2,3-tribromopropane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18859 CHEBI:166 (+)-isodihydrocarvone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_166 CHEBI:165 (1S,4R)-fenchone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_165 CHEBI:160 D-erythro-isocitric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_160 UBERON:0006292 shoulder joint primordium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006292 UBERON:0006291 scapula pre-cartilage condensation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006291 A scapula endochondral element that is composed primarily of a pre-cartilage condensation. UBERON:0006290 scapula cartilage element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006290 A scapula endochondral element that is composed primarily of cartilage tissue. UBERON:0006298 submandibular gland primordium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006298 submaxillary gland primordium A primordium that has the potential to develop into a submandibular gland. UBERON:0006293 spleen primordium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006293 spleen mesenchyme|splenic mesenchyme|left spleen primordium|splenic primordium A dense syncitial-like mesenchymal thickening in the dorsal mesogastrium[ISBN]. the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing spleen[MP]. GO:0004404 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004404 GO:0004403 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004403 GO:0004406 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004406 GO:0004405 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004405 GO:0004400 histidinol-phosphate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004400 RHEA:23744|EC:2.6.1.9|MetaCyc:HISTAMINOTRANS-RXN imidazoleacetol phosphate transaminase activity|glutamic-imidazoleacetol phosphate transaminase activity|imidazolylacetolphosphate aminotransferase activity|IAP transaminase activity|imidazole acetol-phosphate transaminase activity|L-histidinol phosphate aminotransferase activity|histidinol phosphate aminotransferase activity|L-histidinol-phosphate:2-oxoglutarate aminotransferase activity|imidazolylacetolphosphate transaminase activity|histidine:imidazoleacetol phosphate transaminase activity|histidinol-phosphate aminotransferase activity Catalysis of the reaction: L-histidinol-phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate. CHEBI:53128 Se-methylselenocysteinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53128 GO:0004402 histone acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004402 Reactome:R-HSA-3318413|Reactome:R-HSA-3451147|Reactome:R-HSA-3321975|Reactome:R-HSA-3301345|RHEA:21992|Reactome:R-HSA-5250938|Reactome:R-HSA-3662318|Reactome:R-HSA-3697920|MetaCyc:HISTONE-ACETYLTRANSFERASE-RXN|Reactome:R-HSA-5144542|Reactome:R-HSA-3321805|Reactome:R-HSA-3697008|Reactome:R-HSA-3318486|Reactome:R-HSA-3318415|Reactome:R-HSA-3301237|Reactome:R-HSA-3321883|Reactome:R-HSA-3662335|EC:2.3.1.48 acetyl-CoA:histone acetyltransferase activity|H2A/H2B histone acetyltransferase activity|histone transacetylase activity|histone acetokinase activity|H4/H2 histone acetyltransferase activity|nucleosome-histone acetyltransferase activity|H4/H2A acetyltransferase activity|H3/H4 histone acetyltransferase activity|histone acetylase activity|histone lysine acetyltransferase activity Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone. CHEBI:53129 Se-methyl-D-selenocysteinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53129 GO:0004401 histidinol-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004401 KEGG_REACTION:R03013|RHEA:14465|MetaCyc:HISTIDPHOS-RXN|EC:3.1.3.15 histidinol phosphate phosphatase activity|L-histidinol phosphate phosphatase activity|HPpase activity|L-histidinol-phosphate phosphohydrolase activity|histidinolphosphate phosphatase activity|histidinolphosphatase activity Catalysis of the reaction: L-histidinol phosphate + H(2)O = L-histidinol + phosphate. CHEBI:28168 6-oxocyclohex-1-ene-1-carbonyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28168 CHEBI:28164 cholesterol beta-epoxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28164 CHEBI:28163 iron(III) hydroxamate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28163 UBERON:0006322 inferior rectus extraocular muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006322 m. rectus inferior|ventral rectus|inferior rectus muscle|ventral rectus extraocular muscle|musculus rectus inferior|ventral recti|musculus rectus inferior bulbi|inferior rectus A muscle in the orbit that depresses, adducts, and helps extort (rotate laterally) the eye. The inferior rectus muscle is the only muscle that is capable of depressing the pupil when it is in a fully abducted position. CHEBI:28171 5-hydroxytryptophan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28171 UBERON:0006321 superior oblique extraocular muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006321 dorsal oblique extraocular muscle|obliquus oculi superior|M. obliquus superior|dorsal oblique extraocular muscles|superior oblique muscle|musculus obliquus superior|musculus obliquus superior bulbi|superior oblique|obliquus superior The superior oblique muscle, or obliquus oculi superior, is a fusiform muscle in the upper, medial side of the orbit whose primary action is downward, lateral rotation of the eye. One of the extraocular muscles, the superior oblique is the only muscle innervated by the trochlear nerve (the fourth cranial nerve). CHEBI:28173 sorbose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28173 CHEBI:53126 Se-methyl-L-selenocysteinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53126 CHEBI:53125 Se-methyl-D-selenocysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53125 GO:0004408 holocytochrome-c synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004408 EC:4.4.1.17|RHEA:22648|MetaCyc:HOLOCYTOCHROME-C-SYNTHASE-RXN holocytochrome-c apocytochrome-c-lyase (heme-forming)|cytochrome c heme-lyase activity|holocytochrome-c apocytochrome-c-lyase activity|cytochrome c synthase activity|holocytochrome c synthetase activity Catalysis of the reaction: holocytochrome c = apocytochrome c + heme. GO:0004407 histone deacetylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004407 Reactome:R-HSA-3782655|Reactome:R-HSA-2545203|EC:3.5.1.98|Reactome:R-HSA-433672|RHEA:58196|Reactome:R-HSA-3782637|Reactome:R-HSA-6805650|Reactome:R-HSA-2545253|MetaCyc:3.5.1.98-RXN|Reactome:R-HSA-427514|Reactome:R-HSA-3769447|Reactome:R-HSA-3777129 Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction represents the removal of an acetyl group from a histone, a class of proteins complexed to DNA in chromatin and chromosomes. GO:0004409 homoaconitate hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004409 EC:4.2.1.36|RHEA:15485|KEGG_REACTION:R04371|MetaCyc:HOMOACONITATE-HYDRATASE-RXN 2-hydroxybutane-1,2,4-tricarboxylate hydro-lyase activity|(1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate hydro-lyase [(Z)-but-1-ene-1,2,4-tricarboxylate-forming]|homoaconitase activity|cis-homoaconitase activity|Lys4|HACN activity|LysF Catalysis of the reaction: (-)-homoisocitrate = cis-homoaconitate + H(2)O. CHEBI:53121 adenosine A2A receptor antagonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53121 GO:0004415 hyalurononglucosaminidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004415 Reactome:R-HSA-5693356|Reactome:R-HSA-9036077|Reactome:R-HSA-2160892|EC:3.2.1.35|Reactome:R-HSA-2160874|Reactome:R-HSA-1793209|Reactome:R-HSA-2318585|MetaCyc:3.2.1.35-RXN hyaluronoglucosidase activity|chondroitinase activity|chondroitinase I activity|hyaluronoglucosaminidase activity|hyaluronate 4-glycanohydrolase activity|hyaluronidase activity Catalysis of the random hydrolysis of (1->4) linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate. GO:0004414 homoserine O-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004414 KEGG_REACTION:R01776|MetaCyc:HOMOSERINE-O-ACETYLTRANSFERASE-RXN|EC:2.3.1.31|RHEA:13701 homoserine acetyltransferase activity|L-homoserine O-acetyltransferase activity|homoserine O-trans-acetylase activity|acetyl-CoA:L-homoserine O-acetyltransferase activity|homoserine transacetylase activity|homoserine-O-transacetylase activity Catalysis of the reaction: L-homoserine + acetyl-CoA = O-acetyl-L-homoserine + CoA. CHEBI:77109 EC 1.21.3.* (oxidoreductase acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77109 GO:0004417 hydroxyethylthiazole kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004417 MetaCyc:THIAZOLSYN3-RXN|KEGG_REACTION:R04448|RHEA:24212|EC:2.7.1.50 ATP:4-methyl-5-(2-hydroxyethyl)thiazole 2-phosphotransferase activity|hydroxyethylthiazole kinase (phosphorylating)|4-methyl-5-(beta-hydroxyethyl)thiazole kinase activity Catalysis of the reaction: 5-(2-hydroxyethyl)-4-methylthiazole + ATP = 4-methyl-5-(2-phosphoethyl)-thiazole + ADP + 2 H(+). CHEBI:77108 EC 1.1.1.141 [15-hydroxyprostaglandin dehydrogenase (NAD(+))] inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77108 GO:0004416 hydroxyacylglutathione hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004416 Reactome:R-HSA-6783221|RHEA:25245|MetaCyc:GLYOXII-RXN|EC:3.1.2.6 glyoxalase II activity|S-(2-hydroxyacyl)glutathione hydrolase activity|S-2-hydroxylacylglutathione hydrolase activity|acetoacetylglutathione hydrolase activity Catalysis of the reaction: (S)-(2-hydroxyacyl)glutathione + H2O = glutathione + a 2-hydroxy carboxylate. CHEBI:77107 3-[(1-carboxyvinyl)oxy]benzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77107 GO:0004411 homogentisate 1,2-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004411 Reactome:R-HSA-71164|EC:1.13.11.5|KEGG_REACTION:R02519|UM-BBD_reactionID:r0105|RHEA:15449|MetaCyc:HOMOGENTISATE-12-DIOXYGENASE-RXN homogentisicase activity|homogentisic oxygenase activity|homogentisate:oxygen 1,2-oxidoreductase (decyclizing)|homogentisate dioxygenase activity|homogentisate oxidase activity|homogentisate oxygenase activity|homogentisic acid oxidase activity|homogentisic acid oxygenase activity Catalysis of the reaction: homogentisate + O(2) = 4-maleylacetoacetate + H(+). GO:0004410 homocitrate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004410 RHEA:12929|EC:2.3.3.14|MetaCyc:HOMOCITRATE-SYNTHASE-RXN|KEGG_REACTION:R00271 acetyl-coenzyme A:2-ketoglutarate C-acetyl transferase activity|2-hydroxybutane-1,2,4-tricarboxylate 2-oxoglutarate-lyase (CoA-acetylating)|acetyl-CoA:2-oxoglutarate C-acetyltransferase (thioester-hydrolysing, carboxymethyl forming)|2-hydroxybutane-1,2,4-tricarboxylate 2-oxoglutarate-lyase (CoA- acetylating) activity|homocitrate synthetase activity Catalysis of the reaction: 2-oxoglutarate + acetyl-CoA + H(2)O = CoA + H(+) + homocitrate. GO:0004413 homoserine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004413 EC:2.7.1.39|RHEA:13985|KEGG_REACTION:R01771|MetaCyc:HOMOSERKIN-RXN homoserine kinase (phosphorylating)|HSK|ATP:L-homoserine O-phosphotransferase activity Catalysis of the reaction: L-homoserine + ATP = O-phospho-L-homoserine + ADP + 2 H(+). GO:0004412 homoserine dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004412 EC:1.1.1.3|MetaCyc:HOMOSERDEHYDROG-RXN|RHEA:15761 Catalysis of the reaction: L-homoserine + NADP+ = L-aspartate-4-semialdehyde + NADPH + H+. CHEBI:43797 L-propargylglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_43797 CHEBI:43796 (S)-lipoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_43796 CHEBI:28175 beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28175 CHEBI:28177 theophylline biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28177 UBERON:0006311 chamber of eyeball biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006311 eye chamber|eyeball chamber|chamber of eye A segment of the eyeball that is filled with refractive media CHEBI:28181 2',3'-cyclic GMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28181 CHEBI:28180 but-3-ynal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28180 CHEBI:43799 butan-1-amine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_43799 CHEBI:77102 EC 1.3.5.* (oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77102 CHEBI:53112 AMP 3'-end residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53112 GO:0004419 hydroxymethylglutaryl-CoA lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004419 MetaCyc:HYDROXYMETHYLGLUTARYL-COA-LYASE-RXN|Reactome:R-HSA-74180|RHEA:24404|Reactome:R-HSA-6788597|EC:4.1.3.4|KEGG_REACTION:R01360 3-hydroxy-3-methylglutaryl CoA cleaving enzyme|hydroxymethylglutaryl coenzyme A-cleaving enzyme|(S)-3-hydroxy-3-methylglutaryl-CoA acetoacetate-lyase (acetyl-CoA-forming)|hydroxymethylglutaryl coenzyme A lyase activity|3-hydroxy-3-methylglutaryl coenzyme A lyase activity|3-hydroxy-3-methylglutarate-CoA lyase activity|3-hydroxy-3-methylglutaryl-CoA lyase activity|(S)-3-hydroxy-3-methylglutaryl-CoA acetoacetate-lyase activity|HMG-CoA lyase activity Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA. GO:0004418 hydroxymethylbilane synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004418 Reactome:R-HSA-189406|EC:2.5.1.61|MetaCyc:OHMETHYLBILANESYN-RXN|KEGG_REACTION:R00084|RHEA:13185 porphobilinogen:(4-[2-carboxyethyl]-3-[carboxymethyl]pyrrol-2-yl)methyltransferase (hydrolysing)|uroporphyrinogen synthetase activity|pre-uroporphyrinogen synthase activity|(4-(2-carboxyethyl)-3-(carboxymethyl)pyrrol-2-yl)methyltransferase (hydrolyzing) activity|uroporphyrinogen I synthetase activity|uroporphyrinogen synthase activity|(4-[2-carboxyethyl]-3-[carboxymethyl]pyrrol-2-yl)methyltransferase (hydrolysing)|HMB-synthase activity|porphobilinogen deaminase activity|porphobilinogen ammonia-lyase (polymerizing)|uroporphyrinogen I synthase activity Catalysis of the reaction: H(2)O + 4 porphobilinogen = hydroxymethylbilane + 4 NH(4)(+). UBERON:0006314 bodily fluid biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006314 body fluid|fluid Liquid components of living organisms. includes fluids that are excreted or secreted from the body as well as body water that normally is not. UBERON:0006312 ocular refractive media biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006312 Body substance in a liquid or semi-solid state in the eyeball which serves to refract light. CHEBI:77119 EC 1.1.1.189 (prostaglandin-E2 9-reductase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77119 CHEBI:77118 EC 3.5.5.1 (nitrilase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77118 CHEBI:28146 L-xylonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28146 CHEBI:28145 dibenzofuran biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28145 CHEBI:43786 D-glycero-alpha-D-manno-heptose 7-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_43786 CHEBI:28147 N(2')-acetylgentamycin C1a biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28147 CHEBI:28151 5beta,9alpha,10alpha-labda-8(20),13-dien-15-yl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28151 CHEBI:77113 EC 2.7.11.10 (IkappaB kinase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77113 CHEBI:77111 EC 2.1.1.116 [3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase] inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77111 CHEBI:77110 EC 1.21.3.3 (reticuline oxidase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77110 UBERON:0006304 future trigeminal ganglion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006304 trigeminal preganglion|trigeminal V preganglion CHEBI:77117 EC 3.5.5.* (hydrolase acting on C-N bonds in nitriles) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77117 CHEBI:53100 GMP 5'-end residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53100 CHEBI:77115 EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77115 CHEBI:77129 1-stearoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77129 CHEBI:28159 D-asparagine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28159 CHEBI:28161 beta-D-xylose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28161 CHEBI:77124 (4Z,7Z,10Z,13Z,16Z,19Z)-22-hydroxydocosahexaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77124 CHEBI:77122 1-palmitoyl-2-lauroyl-sn-glycero-3-phospho-(1'-sn-glycerol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77122 CHEBI:77121 1-oleoyl-2-lauroyl-sn-glycero-3-phospho-(1'-sn-glycerol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77121 CHEBI:77128 1,2-dilinoleoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77128 CHEBI:77127 1,2-dilinoleoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77127 CHEBI:77126 1,2-diarachidonoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77126 CHEBI:77125 1,2-diarachidonoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77125 OBO:ddanat#part_of part of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/ddanat#part_of part_of CHEBI:28129 all-trans-phytofluene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28129 CHEBI:28125 all-cis-docosa-4,7,10,13,16,19-hexaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28125 CHEBI:28120 L-fructose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28120 CHEBI:28122 p-cumic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28122 CHEBI:77131 sinapic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77131 CHEBI:77130 1-stearoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77130 CHEBI:77135 3-sulfolactaldehyde(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77135 CHEBI:77134 6-deoxy-6-sulfo-D-fructofuranose 1-phosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77134 CHEBI:77133 6-deoxy-6-sulfo-D-fructofuranose(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77133 CHEBI:77132 6-sulfo-D-quinovose(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77132 CHEBI:77139 1-stearoyl-2-oleoyl-sn-glycero-3-phospho-1D-myo-inositol 4-phosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77139 CHEBI:77138 3-sulfopropanediol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77138 CHEBI:77137 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-1D-myo-inositol 4,5-biphosphate(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77137 CHEBI:77136 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-1D-myo-inositol 4-phosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77136 CHEBI:18790 (S)-mevalonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18790 CHEBI:28138 undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28138 CHEBI:28134 ammelide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28134 CHEBI:28137 D-glycero-D-manno-heptose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28137 CHEBI:28130 13,14-dihydro-Delta(12)-prostaglandin J2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28130 CHEBI:28133 S-alkyl-L-cysteine S-oxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28133 UBERON:0006355 superior vesical vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006355 CHEBI:28140 D-quinovose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28140 CHEBI:77142 dTDP-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitroso-beta-L-arabino-hexopyranose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77142 CHEBI:77141 dTDP-beta-L-evernitrose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77141 CHEBI:77140 1-stearoyl-2-oleoyl-sn-glycero-3-phospho-1D-myo-inositol 4,5-biphosphate(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77140 CHEBI:77146 ginsenoside C-K biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77146 CHEBI:77144 dTDP-beta-L-evernosamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77144 CHEBI:77143 dTDP-N-hydroxy-beta-L-evernosamine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77143 CHEBI:77149 notoginsenoside R1 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77149 CHEBI:77148 ginsenoside Re biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77148 CHEBI:28107 2-isopropylmalate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28107 CHEBI:28102 amylose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28102 CHEBI:28101 N(1),N(12)-diacetylspermine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28101 CHEBI:28100 (1->3)-alpha-D-glucan biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28100 UBERON:0006340 fourth ventricle choroid plexus stroma biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006340 A choroid plexus stroma that is part of a fourth ventricle. CHEBI:77152 ginsenoside Rb2 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77152 CHEBI:77150 ginsenoside F1 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77150 CHEBI:77157 ginsenoside C-Y biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77157 CHEBI:77156 gypenoside LXXV biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77156 UBERON:0006347 communicating artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006347 An artery that connects two larger arteries. CHEBI:77159 1-stearoyl-2-linoleoyl-sn-glycero-3-phospho-1D-myo-inositol 5-phosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77159 CHEBI:77158 1-stearoyl-2-linoleoyl-sn-glycero-3-phospho-1D-myo-inositol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77158 PO:0025395 floral organ biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025395 flower organ (exact)|花器官 (Japanese, exact)|órgano floral (Spanish, exact) A plant organ (PO:0009008) that is part of a flower (PO:0009046). CHEBI:28116 5-guanidino-2-oxopentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28116 CHEBI:28119 2,3,7,8-tetrachlorodibenzodioxine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28119 CHEBI:28118 muramic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28118 CHEBI:28113 24,25-dihydrolanosterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28113 CHEBI:43732 thiazole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_43732 CHEBI:28112 nickel atom biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28112 CHEBI:28115 methylcobalamin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28115 CHEBI:77160 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-1D-myo-inositol 5-phosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77160 UBERON:0006331 brainstem nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006331 brain stem nucleus A nucleus of brain that is part of a brainstem. CHEBI:77164 1-stearoyl-2-oleoyl-sn-glycero-3-phospho-1D-myo-inositol 5-phosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77164 CHEBI:77163 1-stearoyl-2-oleoyl-sn-glycero-3-phospho-1D-myo-inositol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77163 CHEBI:77168 14-hydroxymyristic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77168 CHEBI:77167 1,2-dilinoleoyl-sn-glycero-3-phospho-1D-myo-inositol 5-phosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77167 UBERON:0006339 third ventricle choroid plexus stroma biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006339 A choroid plexus stroma that is part of a third ventricle. CHEBI:77166 3-oxo-Delta(1),Delta(4)-steroid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77166 CHEBI:77165 1,2-dilinoleoyl-sn-glycero-3-phospho-1D-myo-inositol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77165 UBERON:0006338 lateral ventricle choroid plexus stroma biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006338 A choroid plexus stroma that is part of a lateral ventricle. UBERON:0006334 posterior lateral line biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006334 pll One of eight distinct lateral lines in the 4-day larva. A sensory system on the surface of the fish, consisting of small sensory patches (neuromasts) distributed in discrete lines over the body surface. The lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance. CHEBI:77169 (3S)-hydroxytetradecanedioyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77169 GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004488 RHEA:22812|KEGG_REACTION:R01220|MetaCyc:METHYLENETHFDEHYDROG-NADP-RXN|EC:1.5.1.5 5,10-methylenetetrahydrofolate:NADP oxidoreductase activity|5,10-methylenetetrahydrofolate:NADP+ oxidoreductase activity Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NADP(+) = 5,10-methenyltetrahydrofolate + NADPH. GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004487 MetaCyc:1.5.1.15-RXN|Reactome:R-HSA-6801462|EC:1.5.1.15|KEGG_REACTION:R01218|RHEA:22892 5,10-methylenetetrahydrofolate dehydrogenase activity|5,10-methylenetetrahydrofolate:NAD+ oxidoreductase Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NAD(+) = 5,10-methenyltetrahydrofolate + NADH. GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004489 MetaCyc:1.5.1.20-RXN|EC:1.5.1.20|KEGG_REACTION:R01224|Reactome:R-HSA-200676|KEGG_REACTION:R07168 5,10-methylenetetrahydrofolic acid reductase activity|5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|5,10-CH(2)-H(4)folate reductase activity|methylenetetrahydrofolate reductase activity|5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|5,10-methylenetetrahydrofolate reductase (FADH2) activity|5,10-CH2-H4folate reductase activity|5,10-methylenetetrahydrofolate reductase (FADH) activity|MTHFR activity|5,10-methylenetetrahydropteroylglutamate reductase activity|N(5),N(10)-methylenetetrahydrofolate reductase activity|5,10-methylenetetrahydrofolate reductase activity|5-methyltetrahydrofolate:NAD oxidoreductase activity|5,10-methylenetetrahydrofolate reductase (NADPH) activity|N(5,10)-methylenetetrahydrofolate reductase activity|5-methyltetrahydrofolate:NADP+ oxidoreductase activity|methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|methylenetetrahydrofolic acid reductase activity|N5,10-methylenetetrahydrofolate reductase activity|methylenetetrahydrofolate reductase (NADPH2)|5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|5-methyltetrahydrofolate:NAD+ oxidoreductase activity|methylenetetrahydrofolate reductase (NADPH(2)) activity|N5,N10-methylenetetrahydrofolate reductase activity|MetF|methylenetetrahydrofolate reductase [NAD(P)H]|5-methyltetrahydrofolate:(acceptor) oxidoreductase activity Catalysis of the reaction: 5-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H + H+. GO:0004484 mRNA guanylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004484 Reactome:R-HSA-77081|EC:2.7.7.50|MetaCyc:MRNA-GUANYLYLTRANSFERASE-RXN|Reactome:R-HSA-77083|RHEA:54592 messenger RNA guanylyltransferase activity|protein lambda2|GTP:mRNA guanylyltransferase activity|mRNA capping enzyme activity|GTP--RNA guanylyltransferase activity Catalysis of the reaction: GTP + (5')pp-Pur-mRNA = diphosphate + G(5')ppp-Pur-mRNA; G(5')ppp-Pur-mRNA is mRNA containing a guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue. GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004483 Reactome:R-HSA-9694721|Reactome:R-HSA-9694499|Reactome:R-HSA-9694521|EC:2.1.1.57|Reactome:R-HSA-9684033|Reactome:R-HSA-9684032|Reactome:R-HSA-9684030|MetaCyc:2.1.1.57-RXN S-adenosyl-L-methionine:mRNA (nucleoside-2'-O-)-methyltransferase activity|messenger RNA (nucleoside-2'-)-methyltransferase activity|mRNA (adenosine-2'-O-)-methyltransferase activity|messenger ribonucleate nucleoside 2'-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + m7G(5')pppR-RNA = S-adenosyl-L-homocysteine + m7G(5')pppRm-RNA. R may be guanosine or adenosine. GO:0004486 methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004486 Reactome:R-HSA-200644|Reactome:R-HSA-200718|EC:1.5.1.5 5,10-methylene-THF dehydrogenase activity|N5,N10-methylenetetrahydrofolate dehydrogenase activity Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NAD(P)+ = 5,10-methenyltetrahydrofolate + NAD(P)H + H+. GO:0004485 methylcrotonoyl-CoA carboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004485 Reactome:R-HSA-508308|MetaCyc:METHYLCROTONYL-COA-CARBOXYLASE-RXN|RHEA:13589|Reactome:R-HSA-70773|KEGG_REACTION:R04138|EC:6.4.1.4 methylcrotonyl coenzyme A carboxylase activity|beta-methylcrotonyl-CoA carboxylase activity|beta-methylcrotonyl coenzyme A carboxylase activity|methylcrotonyl-CoA carboxylase activity|beta-methylcrotonyl CoA carboxylase activity|MCCC activity|3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming) Catalysis of the reaction: 3-methylbut-2-enoyl-CoA + ATP + bicarbonate = trans-3-methylglutaconyl-CoA + ADP + 2 H(+) + phosphate. GO:0004480 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004480 GO:0004482 mRNA (guanine-N7-)-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004482 Reactome:R-HSA-9694737|Reactome:R-HSA-77090|Reactome:R-HSA-9684016|Reactome:R-HSA-9694476|Reactome:R-HSA-9684018|EC:2.1.1.56|Reactome:R-HSA-9684017|MetaCyc:MRNA-GUANINE-N7--METHYLTRANSFERASE-RXN|Reactome:R-HSA-9694492 messenger ribonucleate guanine 7-methyltransferase activity|guanine-7-methyltransferase activity|S-adenosyl-L-methionine:mRNA (guanine-N7-)-methyltransferase activity|messenger RNA guanine 7-methyltransferase activity|S-adenosyl-L-methionine:mRNA (guanine-7-N-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + G(5')pppR-RNA = S-adenosyl-L-homocysteine + m7G(5')pppR-RNA. m7G(5')pppR-RNA is mRNA containing an N7-methylguanine cap; R may be guanosine or adenosine. GO:0004481 methylene-fatty-acyl-phospholipid synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004481 EC:2.1.1.16|RHEA:17549|MetaCyc:2.1.1.16-RXN cyclopropane synthetase activity|S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (methenylating)|unsaturated-phospholipid methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-L-homocysteine + phospholipid methylene fatty acid. GO:0004499 N,N-dimethylaniline monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004499 RHEA:24468|Reactome:R-HSA-217255|MetaCyc:1.14.13.8-RXN|EC:1.14.13.8|Reactome:R-HSA-5602966|Reactome:R-HSA-139970 mixed-function amine oxidase activity|dimethylaniline monooxygenase (N-oxide-forming) activity|flavin monooxygenase activity|flavin-containing monooxygenase activity|methylphenyltetrahydropyridine N-monooxygenase activity|dimethylaniline oxidase activity|dimethylaniline N-oxidase activity|FAD-containing monooxygenase activity|FMO5|Ziegler's enzyme|FMO4|FMO3|FMO2|1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine:oxygen N-oxidoreductase activity|FMO1|DMA oxidase activity|FMO activity|FMO-II|FMO-I|flavin mixed function oxidase activity|N,N-dimethylaniline,NADPH:oxygen oxidoreductase (N-oxide-forming) Catalysis of the reaction: N,N-dimethylaniline + NADPH + H+ + O2 = N,N-dimethylaniline N-oxide + NADP+ + H2O. GO:0004498 calcidiol 1-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004498 KEGG_REACTION:R03610|Reactome:R-HSA-209868|RHEA:20573|MetaCyc:CALCIDIOL-1-MONOOXYGENASE-RXN|EC:1.14.15.18|Reactome:R-HSA-5602186 cytochrome P450 CYP27B|25-hydroxyvitamin D-1 alpha hydroxylase activity|25-hydroxycholecalciferol 1-monooxygenase activity|25-OHD-1 alpha-hydroxylase activity|25-hydroxy vitamin D3 1-alpha-hydroxylase activity|25-hydroxyvitamin D3 1alpha-hydroxylase activity|1-hydroxylase-25-hydroxyvitamin D3 activity|calcidiol,NADPH:oxygen oxidoreductase (1-hydroxylating)|25-hydroxy D3-1alpha-hydroxylase activity|25-hydroxycholecalciferol 1alpha-hydroxylase activity|25-hydroxycholecalciferol 1-hydroxylase activity|25-hydroxycholecalciferol-1-hydroxylase activity Catalysis of the reaction: calcidiol + H(+) + NADPH + O(2) = calcitriol + H(2)O + NADP(+). GO:0004495 mevaldate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004495 Catalysis of the reaction: (R)-mevalonate + acceptor = mevaldate + reduced acceptor. GO:0004494 methylmalonyl-CoA mutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004494 RHEA:22888|Reactome:R-HSA-71010|Reactome:R-HSA-3322971|MetaCyc:METHYLMALONYL-COA-MUT-RXN|UM-BBD_reactionID:r0922|EC:5.4.99.2|KEGG_REACTION:R00833 (R)-methylmalonyl-CoA CoA-carbonylmutase activity|methylmalonyl-CoA CoA-carbonyl mutase activity|(S)-methylmalonyl-CoA mutase activity|methylmalonyl coenzyme A mutase activity|methylmalonyl coenzyme A carbonylmutase activity|(R)-2-methyl-3-oxopropanoyl-CoA CoA-carbonylmutase activity Catalysis of the reaction: (R)-methylmalonyl-CoA = succinyl-CoA. GO:0004497 monooxygenase activity biolink:MolecularActivity go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0004497 Reactome:R-HSA-5423678|Reactome:R-HSA-5662662|Reactome:R-HSA-211962|Reactome:R-HSA-5602295|Reactome:R-HSA-76416|Reactome:R-HSA-212005|Reactome:R-HSA-211959|Reactome:R-HSA-76434|Reactome:R-HSA-211951|Reactome:R-HSA-76426|Reactome:R-HSA-211960|Reactome:R-HSA-5662692|Reactome:R-HSA-215526|Reactome:R-HSA-9027042|Reactome:R-HSA-211919|Reactome:R-HSA-9027302|Reactome:R-HSA-5605147|Reactome:R-HSA-76354|Reactome:R-HSA-9018874|Reactome:R-HSA-9027321|Reactome:R-HSA-211948|Reactome:R-HSA-76397|Reactome:R-HSA-5423664|Reactome:R-HSA-6786239|Reactome:R-HSA-2161814|Reactome:R-HSA-211991|Reactome:R-HSA-211882|Reactome:R-HSA-9027043|Reactome:R-HSA-2161899|Reactome:R-HSA-5423647|Reactome:R-HSA-8865107|Reactome:R-HSA-9027044|Reactome:R-HSA-212004|Reactome:R-HSA-2162191|Reactome:R-HSA-211910|Reactome:R-HSA-76373|Reactome:R-HSA-211904|Reactome:R-HSA-2161890|Reactome:R-HSA-5423672|Reactome:R-HSA-5602242|Reactome:R-HSA-156526|Reactome:R-HSA-211929|Reactome:R-HSA-2161795|Reactome:R-HSA-9037761|Reactome:R-HSA-76472|Reactome:R-HSA-217258|Reactome:R-HSA-213175|Reactome:R-HSA-143468|Reactome:R-HSA-211924|Reactome:R-HSA-211988|Reactome:R-HSA-5602272|Reactome:R-HSA-76466|Reactome:R-HSA-2161940|Reactome:R-HSA-76475|Reactome:R-HSA-76386|Reactome:R-HSA-76456|Reactome:R-HSA-5663050|Reactome:R-HSA-211968 hydroxylase activity Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water. GO:0004496 mevalonate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004496 MetaCyc:MEVALONATE-KINASE-RXN|EC:2.7.1.36|Reactome:R-HSA-191380|KEGG_REACTION:R02245|RHEA:17065 mevalonate 5-phosphotransferase activity|ATP:mevalonate 5-phosphotransferase activity|mevalonic kinase activity|mevalonate phosphokinase activity|mevalonic acid kinase activity|mevalonate kinase (phosphorylating)|MVA kinase activity|ATP:(R)-mevalonate 5-phosphotransferase activity Catalysis of the reaction: (R)-mevalonate + ATP = (R)-5-phosphomevalonate + ADP + 2 H(+). GO:0004491 methylmalonate-semialdehyde dehydrogenase (acylating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004491 MetaCyc:1.2.1.27-RXN|Reactome:R-HSA-70893|EC:1.2.1.27|RHEA:20804 MMSA dehydrogenase activity|2-methyl-3-oxopropanoate:NAD+ 3-oxidoreductase (CoA-propanoylating)|MSDH activity Catalysis of the reaction: 2-methyl-3-oxopropanoate + CoA + NAD+ = propanoyl-CoA + CO2 + NADH + H+. GO:0004490 methylglutaconyl-CoA hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004490 KEGG_REACTION:R02085|MetaCyc:METHYLGLUTACONYL-COA-HYDRATASE-RXN|Reactome:R-HSA-70785|EC:4.2.1.18|RHEA:21536 methylglutaconyl coenzyme A hydratase activity|(S)-3-hydroxy-3-methylglutaryl-CoA hydro-lyase activity|3-methylglutaconyl CoA hydratase activity|methylglutaconase activity|(S)-3-hydroxy-3-methylglutaryl-CoA hydro-lyase (trans-3-methylglutaconyl-CoA-forming) Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA = trans-3-methylglutaconyl-CoA + H(2)O. GO:0004493 methylmalonyl-CoA epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004493 KEGG_REACTION:R02765|RHEA:20553|Reactome:R-HSA-71020|MetaCyc:METHYLMALONYL-COA-EPIM-RXN|EC:5.1.99.1 methylmalonyl coenzyme A racemase activity|2-methyl-3-oxopropanoyl-CoA 2-epimerase activity|methylmalonyl-CoA racemase activity|DL-methylmalonyl-CoA racemase activity|methylmalonyl-CoA 2-epimerase activity Catalysis of the reaction: (R)-methylmalonyl-CoA = (S)-methylmalonyl-CoA. GO:0102801 anthocyanin 5-O-glucoside-4'''-O-malonyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102801 MetaCyc:RXN-8139|RHEA:35515|EC:2.3.1.214 Catalysis of the reaction: 4'''-demalonylsalvianin + malonyl-CoA = salvianin + coenzyme A. GO:0004492 methylmalonyl-CoA decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004492 EC:7.2.4.3|RHEA:21396|MetaCyc:METHYLMALONYL-COA-DECARBOXYLASE-RXN (S)-methylmalonyl-CoA carboxy-lyase (propanoyl-CoA-forming)|(S)-2-methyl-3-oxopropanoyl-CoA carboxy-lyase activity|methylmalonyl-coenzyme A decarboxylase activity|(S)-methylmalonyl-CoA carboxy-lyase activity Catalysis of the reaction: (S)-2-methyl-3-oxopropanoyl-CoA = propanoyl-CoA + CO2. GO:0102800 caffeoyl-CoA:pelargonidin-3,5-diglucoside-6''-O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102800 MetaCyc:RXN-8138 Catalysis of the reaction: anthocyanidin 3,5-di-O-beta-D-glucoside + caffeoyl-CoA = pelargonidin 3-O-(6-O-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside + coenzyme A. GO:0102803 thebane O-demethylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102803 EC:1.14.11.32|MetaCyc:RXN-8149 Catalysis of the reaction: thebaine + 2-oxoglutarate + O2 <=> oripavine + formaldehyde + succinate + carbon dioxide. GO:0102802 thebaine 6-O-demethylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102802 EC:1.14.11.31|MetaCyc:RXN-8147|RHEA:27477 Catalysis of the reaction: thebaine + 2-oxoglutarate + O2 <=> neopinone + formaldehyde + succinate + carbon dioxide. GO:0102805 codeine O-demethylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102805 EC:1.14.11.32|MetaCyc:RXN-8152|RHEA:27413 Catalysis of the reaction: codeine + 2-oxoglutarate + O2 <=> morphine + formaldehyde + succinate + carbon dioxide. GO:0102804 oripavine 6-O-demethylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102804 EC:1.14.11.31|MetaCyc:RXN-8151 Catalysis of the reaction: oripavine + 2-oxoglutarate + O2 <=> morphinone + formaldehyde + succinate + carbon dioxide. CHEBI:7916 pantothenic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_7916 GO:0102807 cyanidin 3-O-glucoside 2''-O-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102807 MetaCyc:RXN-8176 Catalysis of the reaction: UDP-alpha-D-glucose + cyanidin 3-O-beta-D-glucoside betaine <=> cyanidin 3-O-sophoroside + UDP + H+. GO:0102806 4-coumaroyl-CoA:cyanidin-3,5-diglucoside-6''-O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102806 MetaCyc:RXN-8170 Catalysis of the reaction: 4-coumaryl-CoA + cyanin betaine <=> shisonin + coenzyme A. GO:0102809 delphinidin 3-O-glucoside 2''-O-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102809 MetaCyc:RXN-8178 Catalysis of the reaction: UDP-alpha-D-glucose + delphinidin 3-O-beta-D-glucoside <=> H+ + delphinidin 3-O-sophoroside + UDP. GO:0102808 pelargonidin 3-O-glucoside 2''-O-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102808 MetaCyc:RXN-8177 Catalysis of the reaction: UDP-alpha-D-glucose + pelargonidin 3-O-beta-D-glucoside <=> H+ + pelargonidin 3-O-sophoroside + UDP. GO:0004469 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004469 GO:0004466 long-chain-acyl-CoA dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004466 RHEA:17721|MetaCyc:LONG-CHAIN-ACYL-COA-DEHYDROGENASE-RXN|EC:1.3.8.8 long-chain acyl-coenzyme A dehydrogenase activity|palmitoyl-coenzyme A dehydrogenase activity|long-chain-acyl-CoA:(acceptor) 2,3-oxidoreductase activity|long-chain-acyl-CoA:acceptor 2,3-oxidoreductase activity|palmitoyl-CoA dehydrogenase activity Catalysis of the reaction: acyl-CoA + ETF = 2,3-dehydroacyl-CoA + reduced ETF. GO:0004465 lipoprotein lipase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004465 Reactome:R-HSA-174757|Reactome:R-HSA-2395768|Reactome:R-HSA-8979996|Reactome:R-HSA-8980228|Reactome:R-HSA-1482811|MetaCyc:LIPOPROTEIN-LIPASE-RXN|EC:3.1.1.34|Reactome:R-HSA-6789310 clearing factor lipase activity|diacylglycerol hydrolase activity|triacylglycero-protein acylhydrolase activity|diacylglycerol lipase activity|lipemia-clearing factor|postheparin esterase activity|postheparin lipase activity|diglyceride lipase activity Catalysis of the reaction: triacylglycerol + H2O = diacylglycerol + a carboxylate, where the triacylglycerol is part of a lipoprotein. GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004468 Reactome:R-HSA-5693001|MetaCyc:LYSINE-N-ACETYLTRANSFERASE-RXN|Reactome:R-HSA-5618328|RHEA:14417|EC:2.3.1.32 lysine N6-acetyltransferase activity|lysine N(6)-acetyltransferase activity|acetyl-phosphate:L-lysine 6-N-acetyltransferase activity|lysine acetyltransferase activity|LAT activity|acetyl-phosphate:L-lysine N6-acetyltransferase activity Catalysis of the reaction: acetyl phosphate + L-lysine = phosphate + N6-acetyl-L-lysine. GO:0004467 long-chain fatty acid-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004467 MetaCyc:PWY-5143|RHEA:15421|EC:6.2.1.3|Reactome:R-HSA-193766|Reactome:R-HSA-193727|Reactome:R-HSA-5696004|Reactome:R-HSA-201035|Reactome:R-HSA-192137|Reactome:R-HSA-159425|Reactome:R-HSA-193401|UM-BBD_enzymeID:e0025|Reactome:R-HSA-193407|Reactome:R-HSA-2046098|MetaCyc:ACYLCOASYN-RXN|Reactome:R-HSA-2046085|Reactome:R-HSA-193711|Reactome:R-HSA-548843|Reactome:R-HSA-193424|Reactome:R-HSA-193743 long-chain fatty acyl coenzyme A synthetase activity|long chain fatty acyl-CoA synthetase activity|long-chain fatty acid activation|acyl-CoA ligase activity|long-chain acyl CoA synthetase activity|stearoyl-CoA synthetase|pristanoyl-CoA synthetase|thiokinase|lignoceroyl-CoA synthase activity|long-chain acyl-coenzyme A synthetase activity|fatty acid thiokinase (long-chain) activity|long-chain-fatty-acid-CoA ligase activity|LCFA synthetase activity|long-chain acyl-CoA synthetase activity|long-chain-fatty-acyl-CoA synthetase activity|acyl-activating enzyme activity|acyl-CoA synthetase activity Catalysis of the reaction: ATP + a long-chain fatty acid + CoA = AMP + diphosphate + an acyl-CoA; a long-chain fatty acid is a fatty acid with a chain length between C13 and C22. GO:0004462 lactoylglutathione lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004462 RHEA:19069|MetaCyc:GLYOXI-RXN|Reactome:R-HSA-5694071|KEGG_REACTION:R02530|EC:4.4.1.5 (R)-S-lactoylglutathione methylglyoxal-lyase (isomerizing) activity|aldoketomutase activity|glyoxalase I activity|glyoxylase I|(R)-S-lactoylglutathione methylglyoxal-lyase (isomerizing; glutathione-forming)|ketone-aldehyde mutase activity|methylglyoxalase activity Catalysis of the reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal. GO:0004461 lactose synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004461 MetaCyc:LACTOSE-SYNTHASE-RXN|Reactome:R-HSA-5653878|RHEA:12404|EC:2.4.1.22 UDP-galactose:D-glucose 4-beta-D-galactotransferase activity|UDP-galactose-glucose galactosyltransferase activity|lactose synthetase activity|UDPgalactose:D-glucose 4-beta-D-galactotransferase activity|UDPgalactose-glucose galactosyltransferase activity|uridine diphosphogalactose-glucose galactosyltransferase activity Catalysis of the reaction: UDP-galactose + D-glucose = UDP + lactose. GO:0004464 leukotriene-C4 synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004464 MetaCyc:LEUKOTRIENE-C4-SYNTHASE-RXN|Reactome:R-HSA-266050|RHEA:17617|KEGG_REACTION:R03059|EC:4.4.1.20 (7E,9E,11Z,14Z)-(5S,6R)-6-(glutathion-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate glutathione-lyase (epoxide-forming)|LTC4 synthetase activity|LTC(4) synthase activity|(7E,9E,11Z,14Z)-(5S,6R)-5,6-epoxyicosa-7,9,11,14-tetraenoate:glutathione leukotriene-transferase (epoxide-ring-opening)|leukotriene A4:glutathione S-leukotrienyltransferase activity|LTC4 synthase activity|leukotriene C(4) synthetase activity|leukotriene-C4 glutathione-lyase (leukotriene-A4-forming)|leukotriene A(4):glutathione S-leukotrienyltransferase activity|LTC(4) synthetase activity|leukotriene C4 synthetase activity Catalysis of the reaction: leukotriene C(4) = glutathione + leukotriene A(4). GO:0004463 leukotriene-A4 hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004463 MetaCyc:LEUKOTRIENE-A4-HYDROLASE-RXN|Reactome:R-HSA-266072|RHEA:22324|KEGG_REACTION:R03057|EC:3.3.2.6 LTA4 hydrolase activity|(7E,9E,11Z,14Z)-(5S,6S)-5,6-epoxyicosa-7,9,11,14-tetraenoate hydrolase activity|LTA-4 hydrolase activity|leukotriene A4 hydrolase activity|LTA4H|leukotriene A(4) hydrolase activity Catalysis of the reaction: H(2)O + leukotriene A(4) = leukotriene B(4). GO:0102810 glutarate-semialdehyde dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102810 MetaCyc:RXN-8182|RHEA:57832 Catalysis of the reaction: 5-oxopentanoate + NADP + H2O = glutarate + NADPH + 2 H+. GO:0004460 L-lactate dehydrogenase (cytochrome) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004460 EC:1.1.2.3|MetaCyc:L-LACTATE-DEHYDROGENASE-CYTOCHROME-RXN|RHEA:19909 lactic acid dehydrogenase activity|lactate dehydrogenase (cytochrome)|cytochrome b2|cytochrome b2 (flavin-free derivative of flavocytochrome b2)|flavocytochrome b2|dehydrogenase, lactate (cytochrome)|(S)-lactate:ferricytochrome-c 2-oxidoreductase activity|L-lactate cytochrome c reductase activity|L(+)-lactate:cytochrome c oxidoreductase activity|lactic cytochrome c reductase activity|L-lactate ferricytochrome c oxidoreductase activity|L-lactate cytochrome c oxidoreductase activity Catalysis of the reaction: (S)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c. GO:0102812 4-coumaroyl-CoA:cyanidin-3-O-beta-D-glucoside-6''-O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102812 MetaCyc:RXN-8204 Catalysis of the reaction: 4-coumaryl-CoA + cyanidin 3-O-beta-D-glucoside betaine <=> cyanidin 3-(p-coumaroyl)-glucoside + coenzyme A. GO:0102811 geraniol 10-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102811 RHEA:32495|EC:1.14.14.83|MetaCyc:RXN-8197 Catalysis of the reaction: geraniol + O2 + NADPH + H+ <=> (6E)-8-hydroxygeraniol + NADP + H2O. GO:0102814 caffeoyl-CoA:delphinidin-3,5,3'-triglucoside 5-O-glucoside-6-O-hydroxycinnamoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102814 MetaCyc:RXN-8232 Catalysis of the reaction: delphinidin 3,3',5-tri-O-beta-D-glucoside betaine + caffeoyl-CoA <=> delphinidin 3-O-glucosyl-5-O-(caffeoylglucoside-3'-O-glucoside) + coenzyme A. GO:0102813 UDP-D-glucose:cyanidin 3-(p-coumaroyl)-glucoside 5-O-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102813 MetaCyc:RXN-8205 Catalysis of the reaction: UDP-alpha-D-glucose + cyanidin 3-(p-coumaroyl)-glucoside = shisonin + UDP + H+. GO:0102816 UDP-D-glucose:delphinidin 3-O-glucosyl-5-O-caffeoylglucoside -O-beta-D-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102816 RHEA:35423|EC:2.4.1.298|MetaCyc:RXN-8234 Catalysis of the reaction: UDP-alpha-D-glucose + delphinidin 3-O-glucosyl-5-O-caffeoylglucoside <=> H+ + delphinidin 3-O-glucosyl-5-O-(caffeoylglucoside-3'-O-glucoside) + UDP. GO:0102815 caffeoyl-CoA:delphinidin-3,5-diglucoside 5-O-glucoside-6-O-hydroxycinnamoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102815 EC:2.3.1.153|MetaCyc:RXN-8233 Catalysis of the reaction: delphinidin 3-O-beta-D-glucoside-5-O-beta-D-glucoside betaine + caffeoyl-CoA <=> delphinidin 3-O-glucosyl-5-O-caffeoylglucoside + coenzyme A. CHEBI:53183 apo carotenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53183 GO:0102818 lycopene cleavage oxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102818 MetaCyc:RXN-8236 Catalysis of the reaction: lycopene + 2 O2 <=> 2 sulcatone + bixin aldehyde. GO:0102817 caffeoyl-CoA:3-O-glucosyl-5-O-(caffeoylglucoside-3'-O-glucoside) 3'-O-hydroxycinnamoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102817 MetaCyc:RXN-8235 Catalysis of the reaction: delphinidin 3-O-glucosyl-5-O-(caffeoylglucoside-3'-O-glucoside) + caffeoyl-CoA <=> gentiodelphin + coenzyme A. GO:0102819 bixin aldehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102819 MetaCyc:RXN-8237 Catalysis of the reaction: bixin aldehyde + O2 + NAD <=> norbixin + NADH + H+. CHEBI:53186 apo carotenoid diterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53186 CHEBI:53185 apo carotenoid C35 terpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53185 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004477 Reactome:R-HSA-200661|MetaCyc:METHENYLTHFCYCLOHYDRO-RXN|EC:3.5.4.9|RHEA:23700|Reactome:R-HSA-200740|Reactome:R-HSA-6801328 citrovorum factor cyclodehydrase activity|formyl-methenyl-methylenetetrahydrofolate synthetase (combined)|5,10-methenyltetrahydrofolate 5-hydrolase (decyclizing)|5,10-methenyl-THF cyclohydrolase activity Catalysis of the reaction: 5,10-methenyltetrahydrofolate + H2O = 10-formyltetrahydrofolate. GO:0004476 mannose-6-phosphate isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004476 Reactome:R-HSA-532549|MetaCyc:MANNPISOM-RXN|EC:5.3.1.8|RHEA:12356|Reactome:R-HSA-3781832 D-mannose-6-phosphate aldose-ketose-isomerase activity|phosphohexomutase activity|phosphomannoisomerase activity|D-mannose-6-phosphate ketol-isomerase activity|mannose phosphate isomerase activity|phosphomannose isomerase activity|phosphohexoisomerase activity Catalysis of the reaction: D-mannose 6-phosphate = D-fructose 6-phosphate. GO:0004479 methionyl-tRNA formyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004479 EC:2.1.2.9|RHEA:24380|Reactome:R-HSA-5389841|MetaCyc:METHIONYL-TRNA-FORMYLTRANSFERASE-RXN N10-formyltetrahydrofolic-methionyl-transfer ribonucleic transformylase activity|methionyl-tRNA Met formyltransferase activity|formylmethionyl-transfer ribonucleic synthetase activity|mitochondrial N-terminal peptidyl-methionine N-formylation|N(10)-formyltetrahydrofolic-methionyl-transfer ribonucleic transformylase activity|methionyl-transfer ribonucleic transformylase activity|methionyl-transfer ribonucleate methyltransferase activity|conversion of mitochondrial met-tRNAf to fmet-tRNA|methionyl-tRNA transformylase activity|methionyl-transfer RNA transformylase activity|10-formyltetrahydrofolate:L-methionyl-tRNA N-formyltransferase activity|methionyl ribonucleic formyltransferase activity|N-terminal peptidyl-methionine N-formylation|conversion of met-tRNAf to fmet-tRNA Catalysis of the reaction: 10-formyltetrahydrofolate + L-methionyl-tRNA + H2O = tetrahydrofolate + N-formylmethionyl-tRNA. GO:0004478 methionine adenosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004478 Reactome:R-HSA-5603114|Reactome:R-HSA-174391|EC:2.5.1.6|Reactome:R-HSA-5603087|RHEA:21080|MetaCyc:S-ADENMETSYN-RXN adenosylmethionine synthetase activity|S-adenosylmethionine synthetase activity|methionine-activating enzyme|ATP:L-methionine S-adenosyltransferase activity|methionine S-adenosyltransferase activity|S-adenosyl-L-methionine synthetase activity|S-adenosylmethionine synthase activity|AdoMet synthetase activity|ATP-methionine adenosyltransferase activity Catalysis of the reaction: ATP + L-methionine + H2O = phosphate + diphosphate + S-adenosyl-L-methionine. GO:0004473 malate dehydrogenase (decarboxylating) (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004473 KEGG_REACTION:R00216|EC:1.1.1.40|MetaCyc:MALIC-NADP-RXN|Reactome:R-HSA-9012349|Reactome:R-HSA-9012036|RHEA:18253 NADP-malic enzyme activity|NADP-specific malic enzyme|(S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|malate dehydrogenase (NADP, decarboxylating)|malate dehydrogenase (decarboxylating, NADP)|'malic' enzyme|NADP-specific malate dehydrogenase activity|NADP-linked decarboxylating malic enzyme|L-malate:NADP oxidoreductase activity Catalysis of the reaction: (S)-malate + NADP+ = pyruvate + CO2 + NADPH + H+. GO:0004472 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004472 GO:0004475 mannose-1-phosphate guanylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004475 Reactome:R-HSA-446221|KEGG_REACTION:R00885|RHEA:15229|EC:2.7.7.13|MetaCyc:2.7.7.13-RXN PIM-GMP (phosphomannose isomerase-guanosine 5'-diphospho-D-mannose pyrophosphorylase)|GTP-mannose-1-phosphate guanylyltransferase activity|guanosine 5'-diphospho-D-mannose pyrophosphorylase activity|mannose 1-phosphate guanylyltransferase (guanosine triphosphate)|GDP-mannose pyrophosphorylase activity|GTP:mannose-1-phosphate guanylyltransferase activity|guanosine diphosphomannose pyrophosphorylase activity|GTP:alpha-D-mannose-1-phosphate guanylyltransferase activity|guanosine triphosphate-mannose 1-phosphate guanylyltransferase activity Catalysis of the reaction: alpha-D-mannose 1-phosphate + GTP = diphosphate + GDP-alpha-D-mannose. GO:0004474 malate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004474 EC:2.3.3.9|KEGG_REACTION:R00472|MetaCyc:MALSYN-RXN|RHEA:18181 L-malate glyoxylate-lyase (CoA-acetylating) activity|acetyl-CoA:glyoxylate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)|malate condensing enzyme activity|glyoxylate transacetylase activity|malic-condensing enzyme activity|malate synthetase activity|glyoxylic transacetase activity|malic synthetase activity|glyoxylate transacetase activity Catalysis of the reaction: acetyl-CoA + glyoxylate + H(2)O = (S)-malate + CoA + H(+). GO:0102821 bixin methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102821 MetaCyc:RXN-8239 Catalysis of the reaction: bixin + S-adenosyl-L-methionine <=> bixin dimethyl ester + S-adenosyl-L-homocysteine. GO:0102820 norbixin methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102820 MetaCyc:RXN-8238 Catalysis of the reaction: norbixin + S-adenosyl-L-methionine <=> bixin + S-adenosyl-L-homocysteine. GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004471 KEGG_REACTION:R00214|RHEA:12653|MetaCyc:1.1.1.39-RXN|Reactome:R-HSA-9012268|MetaCyc:MALIC-NAD-RXN|EC:1.1.1.39|EC:1.1.1.38 NAD-specific malic enzyme|NAD-malic enzyme activity|(S)-malate:NAD+ oxidoreductase (oxaloacetate-decarboxylating)|NAD-linked malic enzyme|malate dehydrogenase (decarboxylating) activity|(S)-malate:NAD+ oxidoreductase (decarboxylating)|'malic' enzyme|malate dehydrogenase (oxaloacetate-decarboxylating) activity Catalysis of the reaction: (S)-malate + NAD+ = pyruvate + CO2 + NADH + H+. GO:0102823 kaempferol-3-rhamnoside-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102823 MetaCyc:RXN-8266 Catalysis of the reaction: UDP-alpha-D-glucose + kaempferol-3-rhamnoside <=> kaempferol 3-O-rhamnoside-7-O-glucoside + UDP. GO:0004470 malic enzyme activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004470 pyruvic-malic carboxylase activity Catalysis of the oxidative decarboxylation of malate with the concomitant production of pyruvate. GO:0102822 quercetin 3'-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102822 EC:2.1.1.42|MetaCyc:RXN-8262|RHEA:55332 Catalysis of the reaction: quercetin-7-olate + S-adenosyl-L-methionine = H+ + isorhamnetin + S-adenosyl-L-homocysteine. CHEBI:53171 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_53171 GO:0102825 quercetin 3-O-rhamnoside-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102825 MetaCyc:RXN-8268 Catalysis of the reaction: UDP-alpha-D-glucose(2-) + quercetin 3-O-rhamnoside <=> quercetin 3-O-rhamnoside-7-O-glucoside + UDP. GO:0102824 UDP-L-rhamnose:quercetin 3-O-rhamnosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102824 MetaCyc:RXN-8267|RHEA:61160 Catalysis of the reaction: quercetin-7-olate + UDP-L-rhamnose <=> H+ + quercetin 3-O-rhamnoside + UDP. GO:0102827 galactosylononitol-raffinose galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102827 MetaCyc:RXN-8282 Catalysis of the reaction: raffinose + D-galactosylononitol = stachyose + 1D-4-O-methyl-myo-inositol. CHEBI:53173 (3R)-hydroxy-beta-ionone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_53173 GO:0102826 kaempferol-3-glucoside-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102826 MetaCyc:RXN-8270 Catalysis of the reaction: UDP-alpha-D-glucose + kaempferol 3-O-glucoside <=> kaempferol 3,7-O-diglucoside + UDP. GO:0102829 ajugose synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102829 MetaCyc:RXN-8285 Catalysis of the reaction: 2 verbascose <=> ajugose + stachyose. GO:0102828 stachyose galactinol:verbascose galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102828 MetaCyc:RXN-8284 Catalysis of the reaction: stachyose + alpha-D-galactosyl-(1->3)-1D-myo-inositol <=> verbascose + myo-inositol. CHEBI:53175 13-apo-beta-carotenone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_53175 CHEBI:53177 beta-cyclocitral biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_53177 CHEBI:53176 4-methylocta-2,4,6-trienedial biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_53176 GO:0004448 isocitrate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004448 MetaCyc:ISOCITDEH-RXN isocitric dehydrogenase activity|IDP activity|oxalosuccinate decarboxylase activity|oxalosuccinate carboxylase activity|oxalsuccinic decarboxylase activity|beta-ketoglutaric-isocitric carboxylase activity|isocitric acid dehydrogenase activity|IDH activity|IDP3|IDP2|IDP1 Catalysis of the reaction: isocitrate + acceptor = 2-oxoglutarate + CO2 + reduced acceptor. GO:0004447 iodide peroxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004447 EC:1.11.1.8|MetaCyc:IODIDE-PEROXIDASE-RXN|RHEA:23336 monoiodotyrosine deiodinase activity|iodinase activity|iodide:hydrogen-peroxide oxidoreductase activity|iodotyrosine deiodinase activity|TPO activity|thyroperoxidase activity|thyroid peroxidase activity|iodotyrosine deiodase activity|iodide peroxidase-tyrosine iodinase activity|iodoperoxidase (heme type)|tyrosine iodinase activity Catalysis of the reaction: iodide + hydrogen peroxide = iodine + 2 H2O. GO:0004449 isocitrate dehydrogenase (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004449 RHEA:23632|MetaCyc:ISOCITRATE-DEHYDROGENASE-NAD+-RXN|Reactome:R-HSA-70967|EC:1.1.1.41 nicotinamide adenine dinucleotide isocitrate dehydrogenase activity|NAD isocitric dehydrogenase activity|NAD-linked isocitrate dehydrogenase activity|NAD isocitrate dehydrogenase activity|NAD dependent isocitrate dehydrogenase activity|NAD-specific isocitrate dehydrogenase activity|isocitrate:NAD+ oxidoreductase (decarboxylating)|isocitrate dehydrogenase (NAD) activity Catalysis of the reaction: isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH + H+. GO:0004444 obsolete inositol-1,4,5-trisphosphate 1-phosphatase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004444 inositol-1,4,5-trisphosphate 1-phosphatase OBSOLETE. The removal of a phosphate group from the carbon-1 position of D-myo-inositol 1,4,5-trisphosphate. GO:0004443 obsolete inositol-1,4,-bisphosphate 4-phosphatase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004443 inositol-1,4,-bisphosphate 4-phosphatase OBSOLETE. Catalysis of the reaction: D-myo-inositol 3,4-bisphosphate + H2O = D-myo-inositol 3-monophosphate + phosphate. GO:0004446 inositol-hexakisphosphate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004446 EC:3.1.3.62|MetaCyc:RXN-7920 inositol tetrakisphosphate phosphomonoesterase activity|multiple inositol-polyphosphate phosphatase activity|MIPP activity|1D-myo-inositol-hexakisphosphate 5-phosphohydrolase activity Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = myo-inositol pentakisphosphate (mixed isomers) + phosphate. GO:0004445 inositol-polyphosphate 5-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004445 EC:3.1.3.56 type I inositol-polyphosphate phosphatase activity|myo-inositol-1,4,5-trisphosphate 5-phosphatase activity|D-myo-inositol 1,4,5-triphosphate 5-phosphatase activity|InsP(3)/Ins(1,3,4,5)P(4) 5-phosphatase activity|InsP3/Ins(1,3,4,5)P4 5-phosphatase activity|inositol trisphosphate phosphomonoesterase activity|inositol polyphosphate-5-phosphatase activity|inositol triphosphate 5-phosphomonoesterase activity|inosine triphosphatase activity|inositol-1,4,5-trisphosphate/1,3,4,5-tetrakisphosphate 5-phosphatase activity|Ins(1,4,5)P3 5-phosphatase activity|inositol 1,4,5-trisphosphate phosphatase activity|L-myo-inositol 1,4,5-trisphosphate-monoesterase activity|type II inositol polyphosphate 5-phosphatase activity|type II inositol-1,4,5-trisphosphate 5-phosphatase activity|1D-myo-inositol-1,4,5-trisphosphate 5-phosphohydrolase activity|Ins(1,4,5)P(3) 5-phosphatase activity|D-myo-inositol 1,4,5-trisphosphate 5-phosphatase activity|inositol-1,4,5-trisphosphate 5-phosphatase activity|5PTase activity|inositol phosphate 5-phosphomonoesterase activity|D-myo-inositol(1,4,5)/(1,3,4,5)-polyphosphate 5-phosphatase activity|Ins(1,4,5)P3/Ins(1,3,4,5)P4 5-phosphatase activity Catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate. GO:0004440 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004440 GO:0004442 obsolete inositol-1,4,-bisphosphate 3-phosphatase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004442 inositol-1,4,-bisphosphate 3-phosphatase OBSOLETE. Catalysis of the reaction: D-myo-inositol 1,3-bisphosphate + H2O = D-myo-inositol 1-monophosphate + phosphate. GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004441 RHEA:15553|MetaCyc:3.1.3.57-RXN|EC:3.1.3.57|Reactome:R-HSA-1855208 inositol-polyphosphate 1-phosphatase activity|inositol polyphosphate 1-phosphatase activity|1D-myo-inositol-1,4-bisphosphate 1-phosphohydrolase activity Catalysis of the reaction: 1D-myo-inositol 1,4-bisphosphate + H2O = 1D-myo-inositol 4-phosphate + phosphate. CHEBI:53167 hydroxy-beta-cyclocitral biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_53167 PO:0025338 collective plant organ structure development stage biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025338 etapa de desarrollo de una estructura colectiva de la planta (Spanish, exact)|集合的植物構造の発生過程 (Japanese, exact) A plant structure development stage (PO:0009012) that has as primary participant a collective plant structure (PO:0025497). PO:0025337 life of whole plant stage biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025337 植物体の一生 (Japanese, exact)|vida de la planta entera (Spanish, exact) A maximal whole plant development stage. CHEBI:7940 patchouli alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_7940 CHEBI:53166 crocetin dialdehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_53166 GO:0004459 L-lactate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004459 MetaCyc:L-LACTATE-DEHYDROGENASE-RXN|EC:1.1.1.27|Reactome:R-HSA-6807826|Reactome:R-HSA-71849|RHEA:23444|Reactome:R-HSA-70510 L-lactic acid dehydrogenase activity|L-lactic dehydrogenase activity Catalysis of the reaction: (S)-lactate + NAD+ = pyruvate + NADH + H+. GO:0004458 D-lactate dehydrogenase (cytochrome) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004458 RHEA:13521|EC:1.1.2.4|MetaCyc:D-LACTATE-DEHYDROGENASE-CYTOCHROME-RXN (R)-lactate:ferricytochrome-c 2-oxidoreductase activity|D-lactate (cytochrome) dehydrogenase activity|cytochrome-dependent D-(-)-lactate dehydrogenase activity|lactic acid dehydrogenase activity|D-lactate-cytochrome c reductase activity|D-lactate ferricytochrome c oxidoreductase activity|D-(-)-lactic cytochrome c reductase activity Catalysis of the reaction: (R)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c. GO:0004455 ketol-acid reductoisomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004455 EC:1.1.1.86|MetaCyc:ACETOLACTREDUCTOISOM-RXN|RHEA:22068 acetolactate reductoisomerase activity|acetohydroxy acid isomeroreductase activity|acetohydroxy acid reductoisomerase activity|ketol acid reductoisomerase activity|alpha-keto-beta-hydroxylacyl reductoisomerase activity|dihydroxyisovalerate (isomerizing) dehydrogenase activity|reductoisomerase activity|dihydroxyisovalerate dehydrogenase (isomerizing) activity|isomeroreductase activity|2-hydroxy-3-keto acid reductoisomerase activity|(R)-2,3-dihydroxy-3-methylbutanoate:NADP+ oxidoreductase (isomerizing) Catalysis of the reaction: (R)-2,3-dihydroxy-3-methylbutanoate + NADP+ = (S)-2-hydroxy-2-methyl-3-oxobutanoate + NADPH + H+. GO:0004454 ketohexokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004454 MetaCyc:KETOHEXOKINASE-RXN|Reactome:R-HSA-5656459|EC:2.7.1.3|RHEA:18145|Reactome:R-HSA-70333 ATP:D-fructose 1-phosphotransferase activity|hepatic fructokinase activity|ketohexokinase (phosphorylating) Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 1-phosphate. GO:0004457 lactate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004457 Catalysis of the reaction: lactate + NAD+ = H+ + NADH + pyruvate. GO:0004456 phosphogluconate dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004456 EC:4.2.1.12|KEGG_REACTION:R02036|RHEA:17277|MetaCyc:PGLUCONDEHYDRAT-RXN 6-phospho-D-gluconate hydro-lyase (2-dehydro-3-deoxy-6-phospho-D-gluconate-forming)|6-phospho-D-gluconate hydro-lyase activity|gluconate-6-phosphate dehydratase activity|6-phosphogluconate dehydratase activity|6-phosphogluconic dehydrase activity|gluconate 6-phosphate dehydratase activity|6-phosphogluconate dehydrase activity Catalysis of the reaction: 6-phospho-D-gluconate = 2-dehydro-3-deoxy-6-phospho-D-gluconate + H(2)O. GO:0004451 isocitrate lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004451 KEGG_REACTION:R00479|RHEA:13245|EC:4.1.3.1|MetaCyc:ISOCIT-CLEAV-RXN isocitrate glyoxylate-lyase (succinate-forming)|isocitrase activity|isocitrate glyoxylate-lyase activity|ICL activity|isocitratase activity|threo-DS-isocitrate glyoxylate-lyase activity|isocitritase activity Catalysis of the reaction: isocitrate = glyoxylate + succinate. GO:0004450 isocitrate dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004450 Reactome:R-HSA-450984|EC:1.1.1.42|RHEA:19629|Reactome:R-HSA-389540|Reactome:R-HSA-389550|MetaCyc:ISOCITDEH-RXN NADP isocitric dehydrogenase activity|NADP-linked isocitrate dehydrogenase activity|isocitrate dehydrogenase (NADP-dependent) activity|isocitrate (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity|triphosphopyridine nucleotide-linked isocitrate dehydrogenase activity|NADP-specific isocitrate dehydrogenase activity|NADP(+)-linked isocitrate dehydrogenase activity|NADP(+)-ICDH activity|NADP-dependent isocitric dehydrogenase activity|NADP(+)-IDH activity|isocitrate dehydrogenase (NADP) activity|dual-cofactor-specific isocitrate dehydrogenase activity|isocitrate:NADP+ oxidoreductase (decarboxylating)|NADP-dependent isocitrate dehydrogenase activity|isocitrate (NADP) dehydrogenase activity Catalysis of the reaction: isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH + H+. GO:0004453 juvenile-hormone esterase activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0004453 EC:3.1.1.59|MetaCyc:JUVENILE-HORMONE-ESTERASE-RXN|RHEA:16393 JH-esterase activity|juvenile hormone carboxyesterase activity|JH esterase activity|methyl-(2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate acylhydrolase activity|juvenile hormone analog esterase activity Catalysis of the reaction: methyl (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate + H2O = (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate + methanol. A carboxylesterase that hydrolyzes the ester linkage of juvenile hormone. GO:0004452 isopentenyl-diphosphate delta-isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004452 Reactome:R-HSA-191382|KEGG_REACTION:R01123|EC:5.3.3.2|RHEA:23284|MetaCyc:IPPISOM-RXN isopentenyl-diphosphate D-isomerase activity|isopentenyl-diphosphate delta3-delta2-isomerase activity|isopentenylpyrophosphate delta-isomerase activity|IPP isomerase activity|methylbutenylpyrophosphate isomerase activity|isopentenylpyrophosphate isomerase activity Catalysis of the reaction: isopentenyl diphosphate = dimethylallyl diphosphate. CHEBI:53157 4'-apo-beta-carotenal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_53157 CHEBI:53156 polychlorobiphenyl biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53156 CHEBI:53159 (3R)-3-hydroxy-8'-apo-beta-carotenal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_53159 CHEBI:53153 10'-apo-beta-carotenal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_53153 CHEBI:53152 palmitoleoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53152 CHEBI:53155 2,6-dimethylocta-2,4,6-trienedial biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_53155 CHEBI:53154 8'-apo-beta,psi-caroten-8'-al biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_53154 GO:0004426 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004426 GO:0004425 indole-3-glycerol-phosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004425 RHEA:23476|MetaCyc:IGPSYN-RXN|EC:4.1.1.48 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate carboxy-lyase [cyclizing; 1-C-(3-indolyl)-glycerol-3-phosphate-forming]|1-(2-carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate carboxy-lyase (cyclizing)|indoleglycerol phosphate synthetase activity|indole-3-glycerophosphate synthase activity|indoleglycerol phosphate synthase activity Catalysis of the reaction: 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O. GO:0004428 obsolete inositol or phosphatidylinositol kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004428 inositol/phosphatidylinositol kinase activity|inositol or phosphatidylinositol kinase activity OBSOLETE. Catalysis of the phosphorylation of myo-inositol (1,2,3,5/4,6-cyclohexanehexol) or a phosphatidylinositol. GO:0004427 inorganic diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004427 KEGG_REACTION:R00004|Reactome:R-HSA-449937|Reactome:R-HSA-71732|RHEA:24576|EC:3.6.1.1|Reactome:R-HSA-6788912|MetaCyc:INORGPYROPHOSPHAT-RXN inorganic pyrophosphatase activity|diphosphate phosphohydrolase activity|pyrophosphate phosphohydrolase activity Catalysis of the reaction: diphosphate + H(2)O = H(+) + 2 phosphate. GO:0004422 hypoxanthine phosphoribosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004422 EC:2.4.2.8|KEGG_REACTION:R01132|RHEA:17973|Reactome:R-HSA-74215|MetaCyc:HYPOXANPRIBOSYLTRAN-RXN HPRT|guanine-hypoxanthine phosphoribosyltransferase activity|inosinate pyrophosphorylase activity|inosinic pyrophosphorylase activity|IMP-GMP pyrophosphorylase activity|6-hydroxypurine phosphoribosyltransferase activity|IMP pyrophosphorylase activity|inosine 5'-phosphate pyrophosphorylase activity|IMP diphosphorylase activity|IMP:diphosphate phospho-D-ribosyltransferase activity|hypoxanthine-guanine phosphoribosyltransferase activity|inosinic acid pyrophosphorylase activity|6-mercaptopurine phosphoribosyltransferase activity|HGPRTase activity|purine-6-thiol phosphoribosyltransferase activity|Transphosphoribosidase activity Catalysis of the reaction: IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate. GO:0004421 hydroxymethylglutaryl-CoA synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004421 EC:2.3.3.10|RHEA:10188|Reactome:R-HSA-73918|KEGG_REACTION:R01978|MetaCyc:HYDROXYMETHYLGLUTARYL-COA-SYNTHASE-RXN|Reactome:R-HSA-191323 (S)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-acetylating)|3-hydroxy-3-methylglutaryl coenzyme A synthase activity|hydroxymethylglutaryl coenzyme A-condensing enzyme|hydroxymethylglutaryl coenzyme A synthase activity|beta-hydroxy-beta-methylglutaryl-CoA synthase activity|acetyl-CoA:acetoacetyl-CoA C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)|hydroxymethylglutaryl coenzyme alpha-condensing enzyme activity|HMG-CoA synthase activity|(s)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA- acetylating) activity|acetoacetyl coenzyme A transacetase activity|3-hydroxy-3-methylglutaryl coenzyme A synthetase activity|3-hydroxy-3-methylglutaryl-coenzyme A synthase activity|3-hydroxy-3-methylglutaryl-CoA synthase activity|3-hydroxy-3-methylglutaryl CoA synthetase activity Catalysis of the reaction: acetoacetyl-CoA + acetyl-CoA + H(2)O = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H(+). GO:0004424 imidazoleglycerol-phosphate dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004424 KEGG_REACTION:R03457|RHEA:11040|MetaCyc:IMIDPHOSDEHYD-RXN|EC:4.2.1.19 imidazoleglycerol phosphate dehydratase activity|D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate hydro-lyase activity|D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate hydro-lyase [3-(imidazol-4-yl)-2-oxopropyl-phosphate-forming]|IGP dehydratase activity Catalysis of the reaction: D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H(2)O. GO:0004423 iduronate-2-sulfatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004423 EC:3.1.6.13|Reactome:R-HSA-1678650|Reactome:R-HSA-9036046|Reactome:R-HSA-1793182|Reactome:R-HSA-2262743|MetaCyc:3.1.6.13-RXN chondroitinsulfatase|iduronate sulfatase activity|sulfo-L-iduronate sulfatase activity|iduronide-2-sulfate sulfatase activity|iduronate-2-sulphatase activity|L-iduronosulfatase activity|iduronate-2-sulfate sulfatase activity|2-sulfo-L-iduronate 2-sulfatase activity|L-idurono sulfate sulfatase activity|idurono-2-sulfatase activity|iduronate sulfate sulfatase activity|L-iduronate-2-sulfate 2-sulfohydrolase activity|L-iduronate 2-sulfate sulfatase activity|sulfoiduronate sulfohydrolase activity Catalysis of the hydrolysis of the 2-sulfate groups of the L-iduronate 2-sulfate units of dermatan sulfate, heparan sulfate and heparin. CHEBI:28189 isomaltose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28189 GO:0004420 hydroxymethylglutaryl-CoA reductase (NADPH) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004420 MetaCyc:1.1.1.34-RXN|KEGG_REACTION:R02082|Reactome:R-HSA-191352|EC:1.1.1.34|RHEA:15989 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity|HMG-CoA reductase activity Catalysis of the reaction: (R)-mevalonate + CoA + 2 NADP(+) = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADPH. CHEBI:28185 kanamycin C biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28185 CHEBI:28193 lupanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28193 CHEBI:28192 2-demethylmenaquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28192 CHEBI:28195 3alpha-hydroxy-5beta-androstan-17-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28195 CHEBI:28194 petroselinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28194 CHEBI:28191 6-alpha-maltosylglucose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28191 CHEBI:53146 (2Z,4E)-2-hydroxymuconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53146 PO:0025314 microsporangium tapetum biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025314 小胞子嚢絨毯組織（タペート組織） (Japanese, exact)|tapeto del microsporangio (Spanish, exact) An tapetum (PO:0025313) that is part of a microsporangium wall (PO:0025307). PO:0025313 tapetum biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025313 tapeto (Spanish, exact)|絨毯組織、タペート組織 (Japanese, exact) A portion of ground tissue (PO:0025059) that is the inner-most layer of a sporangium wall (PO:0025306). GO:0004429 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004429 GO:0004437 obsolete inositol or phosphatidylinositol phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004437 inositol/phosphatidylinositol phosphatase activity|inositol or phosphatidylinositol phosphatase activity OBSOLETE. Catalysis of the removal of a phosphate group from phosphorylated myo-inositol (1,2,3,5/4,6-cyclohexanehexol) or a phosphatidylinositol. GO:0004436 phosphatidylinositol diacylglycerol-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004436 MetaCyc:3.1.4.10-RXN|RHEA:17093|EC:4.6.1.13 1-phosphatidyl-1D-myo-inositol diacylglycerol-lyase (1,2-cyclic-phosphate-forming)|1-phosphatidyl-D-myo-inositol inositolphosphohydrolase (cyclic-phosphate-forming)|1-phosphatidylinositol phosphodiesterase activity|1-phosphatidyl-1D-myo-inositol diacyl-sn-glycerol-lyase (1D-myo-inositol-1,2-cyclic-phosphate-forming)|monophosphatidylinositol phosphodiesterase activity Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol = D-myo-inositol 1,2-cyclic phosphate + diacylglycerol. GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004439 Reactome:R-HSA-1675824|Reactome:R-HSA-1676177|EC:3.1.3.36|MetaCyc:PHOSPHATIDYLINOSITOL-BISPHOSPHATASE-RXN|KEGG_REACTION:R04404|RHEA:22764|Reactome:R-HSA-8868648 triphosphoinositide phosphomonoesterase activity|phosphatidylinositol-bisphosphatase activity|phosphatidylinositol 4,5-bisphosphate phosphatase activity|PtdIns(4,5)P(2) 5-phosphatase activity|PI(4,5)P2 5-phosphatase activity|triphosphoinositide phosphatase activity|PtdIns(4,5)P2 5-phosphatase activity|phosphatidyl-myo-inositol-4,5-bisphosphate phosphatase activity Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate. GO:0004438 phosphatidylinositol-3-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004438 Reactome:R-HSA-1676141|Reactome:R-HSA-6809975|MetaCyc:PHOSPHATIDYLINOSITOL-3-PHOSPHATASE-RXN|Reactome:R-HSA-6809777|Reactome:R-HSA-6809325|Reactome:R-HSA-1675795|Reactome:R-HSA-1675994|RHEA:12316|Reactome:R-HSA-1676114|EC:3.1.3.64|Reactome:R-HSA-6809720 inositol-1,3-bisphosphate 3-phosphatase activity|inositol-1,4,-bisphosphate 3-phosphatase activity|inositol 1,3-bisphosphate phosphatase activity|1-phosphatidyl-1D-myo-inositol-3-phosphate 3-phosphohydrolase activity|D-myo-inositol-1,3-bisphosphate 3-phosphohydrolase activity|inositol-polyphosphate 3-phosphatase activity|phosphatidyl-3-phosphate 3-phosphohydrolase activity Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3-phosphate + H2O = 1-phosphatidyl-1D-myo-inositol + phosphate. GO:0004433 obsolete 1-phosphatidylinositol-4-phosphate kinase, class IB biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004433 1-phosphatidylinositol-4-phosphate kinase, class IB OBSOLETE. A class I PI3K activated via heterotrimeric G-proteins. GO:0004432 obsolete 1-phosphatidylinositol-4-phosphate kinase, class IA biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004432 1-phosphatidylinositol-4-phosphate kinase, class IA OBSOLETE. A class I PI3K activated by tyrosine phosphorylation events. GO:0004435 phosphatidylinositol phospholipase C activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004435 Reactome:R-HSA-111879|Reactome:R-HSA-2730847|Reactome:R-HSA-1855214|Reactome:R-HSA-202407|EC:3.1.4.11|Reactome:R-HSA-9032478|KEGG_REACTION:R03435|Reactome:R-HSA-1855221|RHEA:33179|Reactome:R-HSA-5607735|Reactome:R-HSA-167686|Reactome:R-HSA-1855177|Reactome:R-HSA-622382|MetaCyc:3.1.4.11-RXN monophosphatidylinositol phosphodiesterase activity|PI-PLC activity|phosphoinositide phospholipase C activity|phosphatidylinositol-4,5-bisphosphate hydrolysis|1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase activity|1-phosphatidyl-D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase activity|phosphoinositidase C activity|triphosphoinositide phosphodiesterase activity|1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase activity Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1,2-diacylglycerol + 1D-myo-inositol 1,4,5-trisphosphate + H(+). GO:0004434 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004434 GO:0004431 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004431 GO:0004430 1-phosphatidylinositol 4-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004430 MetaCyc:1-PHOSPHATIDYLINOSITOL-KINASE-RXN|Reactome:R-HSA-1675813|EC:2.7.1.67|Reactome:R-HSA-1675883|Reactome:R-HSA-1675974|RHEA:19877|Reactome:R-HSA-1676185|KEGG_REACTION:R03361|Reactome:R-HSA-1675780 PI4-kinase activity|phosphatidylinositol 4-kinase activity|PtdIns-4-kinase activity|type II phosphatidylinositol kinase activity|PI 4-kinase activity|phosphatidylinositol kinase activity|PI4K|PI4K-alpha activity|ATP:1-phosphatidyl-1D-myo-inositol 4-phosphotransferase activity|phosphatidylinositol kinase (phosphorylating) activity|PI kinase activity Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = 1-phosphatidyl-1D-myo-inositol 4-phosphate + ADP + 2 H(+). CHEBI:28197 daidzein biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28197 CHEBI:28196 erythromycin B biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28196 CHEBI:28199 ferrienterobactin(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28199 CHEBI:7934 paromomycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_7934 CHEBI:7933 paromamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_7933 PO:0025307 microsporangium wall biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025307 pared del microsporangio (Spanish, exact)|小胞子嚢壁 (Japanese, exact) A sporangium wall (PO:0025306) that is part of a microsporangium (PO:0025202). PO:0025306 sporangium wall biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025306 pared del esporangio (Spanish, exact)|sporangium jacket layers (exact)|sporangium jacket layer (exact)|胞子嚢壁 (Japanese, exact) A cardinal organ part (PO:0025001) that is composed of the outer layers of a sporangium (PO:0025094) and bounds the archesporium (PO:0030074) or plant spores (PO:0025017). CHEBI:53131 Se-methyl-D-selenocysteinium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53131 CHEBI:53130 Se-methyl-L-selenocysteinium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53130 CHEBI:53132 Se-methylselenocysteinium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53132 CHEBI:7747 oleuropein biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_7747 CHEBI:7754 oligonucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_7754 CHEBI:7735 olanzapine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_7735 CHEBI:7794 phosphate monoester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_7794 CHEBI:137799 deoxycholic acid 24-O-(beta-D-glucuronide) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137799 CHEBI:137791 cholic acid 24-O-(beta-D-glucuronide) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137791 CHEBI:137790 chenodeoxycholic acid 24-O-(beta-D-glucuronide) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137790 CHEBI:137796 2,5,6-triamino-4-hydroxypyrimidine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137796 CHEBI:53091 carbodiimide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53091 CHEBI:7775 ononin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_7775 CHEBI:77050 (S,S)-pavine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77050 CHEBI:468 poly[(1->4)-beta-D-mannuronic acid] biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_468 CHEBI:43722 isomyristic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_43722 CHEBI:77051 2,3,8,9-tetramethoxy-5,6,11,12-tetrahydro-5,11-epiminodibenzo[a,e][8]annulene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77051 CHEBI:77055 argemonine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77055 CHEBI:77059 (+)-argemonine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77059 CHEBI:77061 4,8-dimethylnonanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77061 CHEBI:77060 2,3,8,9-tetramethoxy-13-methyl-5,6,11,12-tetrahydro-5,11-epiminodibenzo[a,e][8]annulene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77060 CHEBI:77065 beta-citrylglutamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77065 CHEBI:77064 Ac-Asp-Glu-Glu biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77064 CHEBI:77063 4,8-dimethylnonanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77063 CHEBI:43711 (R)-dihydrolipoamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_43711 CHEBI:18743 (S)-2-trans-abscisic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18743 CHEBI:77068 sphingoid 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77068 CHEBI:43703 beta-L-fructofuranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_43703 CHEBI:77076 10-carboxy-13-deoxydaunorubicin zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77076 CHEBI:77075 (2E)-hexadecenedioyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77075 CHEBI:77074 4-O-methylrhodomycin D(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77074 CHEBI:77073 rhodomycin D(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77073 CHEBI:488 1,2-campholide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_488 CHEBI:77079 (3R)-hydroxyhexadecanedioyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77079 CHEBI:77077 10-carboxy-13-deoxycarminomycin zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77077 CHEBI:77090 EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77090 CHEBI:77081 3-oxohexadecanedioyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77081 CHEBI:77080 (3S)-hydroxyhexadecanedioyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77080 CHEBI:77087 O-hexadecanedioyl-L-carnitine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77087 CHEBI:77086 O-lauroyl-L-carnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77086 CHEBI:77085 hexadecanedioyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77085 CHEBI:77084 tetradecanedioyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77084 CHEBI:77089 EC 2.5.1.49 (O-acetylhomoserine aminocarboxypropyltransferase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77089 CHEBI:77094 1-icosanoyl-2-arachidonoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77094 CHEBI:77093 1-icosanoyl-2-arachidonoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77093 CHEBI:77092 fenbendazole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77092 CHEBI:77091 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77091 CHEBI:77098 1-stearoyl-2-linoleoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77098 CHEBI:77097 1-stearoyl-2-linoleoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77097 CHEBI:77096 1-palmitoyl-2-arachidonoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77096 CHEBI:77099 (2S)-pristanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77099 CHEBI:18703 D-pipecolate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18703 PR:000015288 smoothened biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000015288 SMO|protein Gx|SMOH A frizzled-like G-protein coupled receptor that is a translation product of the human SMO gene or a 1:1 ortholog thereof. CHEBI:18723 nicotine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18723 GO:0004525 ribonuclease III activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004525 Reactome:R-HSA-426464|EC:3.1.26.3|Reactome:R-HSA-203893|MetaCyc:3.1.26.3-RXN|Reactome:R-HSA-203862 pre-mRNA 3'-end processing endonuclease|RNase III activity|ribonuclease 3 activity Catalysis of the endonucleolytic cleavage of RNA with 5'-phosphomonoesters and 3'-OH termini; makes two staggered cuts in both strands of dsRNA, leaving a 3' overhang of 2 nt. GO:0004524 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004524 PO:0025023 collective phyllome structure biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025023 floral whorl (narrow)|phyllome whorl (related)|whorl (narrow)|verticil (broad)|cycle (broad)|estructura colectiva del filoma (Spanish, exact)|葉的器官が集まった構造 (Japanese, exact) A collective plant organ structure (PO:0025007) that consists of two or more phyllomes (PO:0006001) originating from the same node or from one or more adjacent nodes with compressed shoot internodes (PO:0005005). GO:0004527 exonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004527 exonuclease IX activity Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end. GO:0004526 ribonuclease P activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004526 EC:3.1.26.5|MetaCyc:3.1.26.5-RXN|Reactome:R-HSA-5696810|Wikipedia:RNase_P tRNA 5' leader endonuclease activity|RNase P Catalysis of the endonucleolytic cleavage of RNA, removing 5' extra nucleotides from tRNA precursor. GO:0004521 endoribonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004521 Reactome:R-HSA-9009941|Reactome:R-HSA-927836|Reactome:R-HSA-426520|Reactome:R-HSA-425923|Reactome:R-HSA-9023909|Reactome:R-HSA-6814555|Reactome:R-HSA-9023912|Reactome:R-HSA-5601910|Reactome:R-HSA-9009936|Reactome:R-HSA-5601887|Reactome:R-HSA-6791223 endonuclease G activity Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks. GO:0004520 endodeoxyribonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004520 Reactome:R-HSA-9023941|Reactome:R-HSA-5693608|Reactome:R-HSA-6782224|Reactome:R-HSA-5690988|Reactome:R-HSA-110359|Reactome:R-HSA-6782204|Reactome:R-HSA-5686657|Reactome:R-HSA-5687464|Reactome:R-HSA-5693584|Reactome:R-HSA-5686440 DNA nicking activity|endonuclease G activity Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks. GO:0004523 RNA-DNA hybrid ribonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004523 EC:3.1.26.4|Reactome:R-HSA-164528|Reactome:R-HSA-164519|Reactome:R-HSA-173769|MetaCyc:3.1.26.4-RXN|Reactome:R-HSA-182859|Reactome:R-HSA-182795 RNase H1 activity|RNase H2 activity|RNase H3 activity|hybrid nuclease activity|RNA*DNA hybrid ribonucleotidohydrolase activity|hybrid ribonuclease activity|ribonuclease H activity|calf thymus ribonuclease H activity|endoribonuclease H (calf thymus)|RNase H activity|hybridase (ribonuclease H)|ribonuclease H1 activity|endoribonuclease H|ribonuclease H2 activity|ribonuclease H3 activity|hybridase activity|endoribonuclease0 H activity Catalysis of the endonucleolytic cleavage of RNA in RNA-DNA hybrids to 5'-phosphomonoesters. GO:0004522 ribonuclease A activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004522 EC:4.6.1.18|MetaCyc:3.1.27.5-RXN|Wikipedia:Ribonuclease_A gene S locus-specific glycoproteins|alkaline ribonuclease activity|ribonuclease I activity|endoribonuclease I|pancreatic ribonuclease activity|ribonucleic phosphatase activity|SLSG glycoproteins|ribonucleate 3'-pyrimidino-oligonucleotidohydrolase activity|gene S glycoproteins|RNase A activity|S-genotype-assocd. glycoproteins|RNase activity|pancreatic RNase activity|RNase I activity|ceratitis capitata alkaline ribonuclease activity Catalysis of the endonucleolytic cleavage of RNA to 3'-phosphomononucleotides and 3'-phosphooligonucleotides ending in C-P or U-P with 2',3'-cyclic phosphate intermediates. CHEBI:28047 5beta-cholestane-3alpha,7alpha-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28047 CHEBI:137818 7-oxoglycolithocholate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137818 CHEBI:137817 hyocholic acid 24-O-(beta-D-glucuronide) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137817 PR:000005870 corticotropin-releasing factor receptor 2 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000005870 CRF2R|corticotropin-releasing hormone receptor 2|CRF-RB|CRH-R-2|CRF-R-2|CRFR-2|CRHR2|CRF-R2|CRH2R|CRH-R2 A corticotropin-releasing factor receptor that is a translation product of the human CRHR2 gene or a 1:1 ortholog thereof. CHEBI:28045 (2,2,3-trimethyl-5-oxocyclopent-3-en-1-yl)acetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28045 CHEBI:28044 phenylalanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28044 CHEBI:137811 phenolic radical biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137811 CHEBI:137812 hyodeoxycholic acid 24-O-(beta-D-glucuronide) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137812 PR:000005869 corticotropin-releasing factor receptor 1 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000005869 corticotropin-releasing hormone receptor 1|CRH-R-1|CRF-R-1|CRFR-1|CRHR1|CRFR|CRF-R1|CRHR|CRH-R1|CRFR1 A corticotropin-releasing factor receptor that is a translation product of the human CRHR1 gene or a 1:1 ortholog thereof. GO:0004529 exodeoxyribonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004529 Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a DNA molecule. PO:0025017 plant spore biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025017 espora (Spanish, exact)|diaspore (broad)|spore (broad)|植物胞子 (Japanese, exact) A whole plant (PO:0000003) that arises through meiosis and is contained in a spore wall. GO:0004528 phosphodiesterase I activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004528 EC:3.1.4.1|MetaCyc:3.1.4.1-RXN alkaline phosphodiesterase activity|5'NPDE activity|5'-PDE activity|PDE I activity|5'-exonuclease activity|exonuclease I activity|5'-PDase activity|orthophosphoric diester phosphohydrolase activity|5'-phosphodiesterase activity|phosphodiesterase activity|5'-nucleotide phosphodiesterase activity|5'-NPDase activity|5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity|nucleotide pyrophosphatase/phosphodiesterase I activity|oligonucleate 5'-nucleotidohydrolase activity Catalysis of the sequential hydrolytic removal of 5'-nucleotides from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides. CHEBI:53000 epitope biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53000 GO:0004536 deoxyribonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004536 Reactome:R-HSA-6785986|Reactome:R-HSA-211247|Reactome:R-HSA-5685994 caspase-activated deoxyribonuclease activity Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid. GO:0004535 poly(A)-specific ribonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004535 MetaCyc:3.1.13.4-RXN|Reactome:R-HSA-430021|Reactome:R-HSA-429992|Reactome:R-HSA-429955|EC:3.1.13.4 2',3'-exoribonuclease activity|poly(A)-specific RNase activity|3'-exoribonuclease activity Catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP. GO:0004537 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004537 GO:0004532 exoribonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004532 Reactome:R-HSA-429961 Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of an RNA molecule. GO:0004531 deoxyribonuclease II activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004531 MetaCyc:3.1.22.1-RXN|EC:3.1.22.1 deoxyribonucleate 3'-nucleotidohydrolase activity|DNase II activity|lysosomal DNase II activity|pancreatic DNase II|acid DNase activity|acid deoxyribonuclease activity Catalysis of the endonucleolytic cleavage of DNA to 3'-phosphodinucleotide and 3'-phosphooligonucleotide end products. GO:0004534 5'-3' exoribonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004534 EC:3.1.13.-|Reactome:R-HSA-429845 Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of an RNA molecule. GO:0004533 exoribonuclease H activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004533 MetaCyc:3.1.13.2-RXN|EC:3.1.13.2 retroviral reverse transcriptase RNaseH Catalysis of the exonucleolytic cleavage of RNA to 5'-phosphomonoester oligonucleotides in both 5' to 3' and 3' to 5' directions. CHEBI:28058 alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28058 CHEBI:137829 hyocholic acid 6-O-(beta-D-glucuronide) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137829 CHEBI:28057 amylopectin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28057 GO:0004530 deoxyribonuclease I activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004530 MetaCyc:3.1.21.1-RXN|EC:3.1.21.1 Escherichia coli endonuclease I|deoxyribonuclease (pancreatic)|thymonuclease activity|DNA endonuclease activity|DNAase activity|deoxyribonuclease A|DNase I|alkaline DNase activity|DNase activity|pancreatic DNase activity|alkaline deoxyribonuclease activity|DNA nuclease activity|deoxyribonucleic phosphatase activity|endodeoxyribonuclease I|dornava|pancreatic deoxyribonuclease|DNA depolymerase activity|dornavac|pancreatic dornase|thymonuclease, dornase activity Catalysis of the endonucleolytic cleavage of DNA to 5'-phosphodinucleotide and 5'-phosphooligonucleotide end products. CHEBI:28059 cis-1,2-dithiane-4,5-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28059 CHEBI:28054 o-cresol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28054 CHEBI:28053 melibiose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28053 CHEBI:137822 hyodeoxycholic acid 6-O-(beta-D-glucuronide) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137822 CHEBI:28061 alpha-D-galactose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28061 UBERON_CORE:subdivision_of subdivision of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/uberon/core#subdivision_of subdivision_of CHEBI:28063 o-xylene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28063 CHEBI:137820 7-oxotaurodeoxycholate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137820 CHEBI:137824 7-oxoglycodeoxycholate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137824 PO:0025007 collective plant organ structure biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025007 集合植物器官構造 (Japanese, exact)|estructura vegetal colectiva de órgano (Spanish, exact) A collective plant structure (PO:0025497) that is a proper part of a whole plant (PO:0000003), and is composed of two or more adjacent plant organs (PO:0009008) and the associated portions of plant tissue (PO:0009007). PO:0025006 plant gamete biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025006 配偶子 (Japanese, exact)|gameta (Spanish, exact) A native plant cell (PO:0025606) that has half the chromosome complement of the sporophyte and is capable of fertilization to create a plant zygote (PO:0000423). PO:0025004 plant axis biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025004 植物軸（軸柱） (Japanese, exact)|plant axes (exact, plural)|eje de la planta (Spanish, exact) An axial plant organ (PO:0009008). GO:0004503 monophenol monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004503 EC:1.14.18.1|MetaCyc:MONOPHENOL-MONOOXYGENASE-RXN|RHEA:18117 cresolase activity|prophenoloxidase activity|phenolase activity|tyrosinase activity|o-diphenol oxidoreductase|monophenol dihydroxyphenylalanine:oxygen oxidoreductase activity|monophenol,L-dopa:oxygen oxidoreductase activity|L-tyrosine monooxygenase activity|dopa oxidase|chlorogenic acid oxidase activity|polyphenolase activity|phenol oxidase activity|tyrosine-dopa oxidase activity|catecholase|prophenol oxidase activity|monophenol monooxidase activity|pyrocatechol oxidase|monophenol, dihydroxy-L-phenylalanine oxygen oxidoreductase activity|o-diphenol oxidase activity|monophenol oxidase activity|monophenolase activity|monophenol oxygenase|chlorogenic oxidase activity|N-acetyl-6-hydroxytryptophan oxidase activity|o-diphenol:oxygen oxidoreductase|o-diphenol:O2 oxidoreductase activity|polyaromatic oxidase activity Catalysis of the reaction: L-tyrosine + L-DOPA + O2 = L-DOPA + DOPAquinone + H2O. GO:0004502 kynurenine 3-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004502 EC:1.14.13.9|RHEA:20545|MetaCyc:KYNURENINE-3-MONOOXYGENASE-RXN|Reactome:R-HSA-71200|KEGG_REACTION:R01960 kynurenine 3-hydroxylase activity|L-kynurenine,NADPH:oxygen oxidoreductase (3-hydroxylating)|L-kynurenine-3-hydroxylase activity|kynurenine hydroxylase activity Catalysis of the reaction: L-kynurenine + H(+) + NADPH + O(2) = 3-hydroxy-L-kynurenine + H(2)O + NADP(+). PO:0025001 cardinal organ part biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025001 基本的な（主要な）器官部 (Japanese, exact)|parte de un órgano cardinal (Spanish, exact)|cardinal part of plant organ (exact) A cardinal part of multi-tissue plant structure (PO:0025498) that is a proper part of a plant organ (PO:0009008) and includes portions of plant tissue (PO:0009007) of at least two different types. GO:0004505 phenylalanine 4-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004505 RHEA:20273|MetaCyc:PHENYLALANINE-4-MONOOXYGENASE-RXN|Reactome:R-HSA-5649483|Reactome:R-HSA-71118|EC:1.14.16.1 L-phenylalanine,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating)|phenylalanine hydroxylase activity|phenylalaninase activity|phenylalanine 4-hydroxylase activity|PAH activity Catalysis of the reaction: L-phenylalanine + tetrahydrobiopterin + O2 = L-tyrosine + 4-alpha-hydroxytetrahydrobiopterin. GO:0004504 peptidylglycine monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004504 EC:1.14.17.3|MetaCyc:PEPTIDYLGLYCINE-MONOOXYGENASE-RXN|RHEA:21452 peptide alpha-amide synthase activity|peptidylglycine 2-hydroxylase activity|peptide alpha-amidating enzyme|synthase, peptide alpha-amide|PAM activity|peptidylglycine,ascorbate:oxygen oxidoreductase (2-hydroxylating)|PAM-B|PAM-A|peptidyl alpha-amidating enzyme activity|peptidylglycine alpha-hydroxylase activity|peptidylglycine alpha-amidating monooxygenase activity|peptide-alpha-amide synthetase activity Catalysis of the reaction: peptidyl-glycine + ascorbate + O2 = peptidyl(2-hydroxyglycine) + dehydroascorbate + H2O. GO:0004501 ecdysone 20-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004501 RHEA:14021|EC:1.14.99.22|MetaCyc:ECDYSONE-20-MONOOXYGENASE-RXN|KEGG_REACTION:R02374 ecdysone,hydrogen-donor:oxygen oxidoreductase (20-hydroxylating)|alpha-ecdysone C-20 hydroxylase activity|ecdysone 20-hydroxylase activity|ecdysone modification Catalysis of the reaction: AH(2) + Ecdysone + O(2) = 20-hydroxyecdysone + A + H(2)O. GO:0004500 dopamine beta-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004500 EC:1.14.17.1|MetaCyc:DOPAMINE-BETA-MONOOXYGENASE-RXN|KEGG_REACTION:R02535|Reactome:R-HSA-209891|RHEA:19117 phenylamine beta-hydroxylase activity|dopa beta-hydroxylase activity|SDBH (soluble dopamine beta-monooxygenase)|dopamine beta-oxidase activity|MDBH (membrane-associated dopamine beta-monooxygenase)|dopamine hydroxylase activity|4-(2-aminoethyl)pyrocatechol beta-oxidase activity|dopamine beta-hydroxylase activity|dopamine b-hydroxylase activity|dopamine-B-hydroxylase activity|3,4-dihydroxyphenethylamine beta-oxidase activity|(3,4-dihydroxyphenethylamine)beta-mono-oxygenase activity|oxygenase, dopamine beta-mono-|3,4-dihydroxyphenethylamine,ascorbate:oxygen oxidoreductase (beta-hydroxylating) Catalysis of the reaction: L-ascorbate + dopamine + O(2) = (R)-noradrenaline + dehydroascorbate + H(2)O. CHEBI:28024 cyanic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28024 CHEBI:28026 plastoquinol-9 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28026 CHEBI:28030 L-2-amino-4-(hydroxymethylphosphinoyl)butanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28030 GO:0004507 steroid 11-beta-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004507 EC:1.14.15.4|MetaCyc:STEROID-11-BETA-MONOOXYGENASE-RXN|Reactome:R-HSA-193997|Reactome:R-HSA-5580292|RHEA:15629|Reactome:R-HSA-5600598|Reactome:R-HSA-194017 steroid 11beta-monooxygenase activity|cytochrome P450 CYP11B2|cytochrome P450 CYP11B1|steroid 11beta-hydroxylase activity|cytochrome p450 XIB1 activity|steroid 11-beta/18-hydroxylase activity|steroid 11beta/18-hydroxylase activity|oxygenase, steroid 11beta -mono-|steroid,reduced-adrenal-ferredoxin:oxygen oxidoreductase (11beta-hydroxylating)|steroid 11-beta-hydroxylase activity Catalysis of the reaction: a steroid + reduced adrenal ferredoxin + O2 = an 11-beta-hydroxysteroid + oxidized adrenal ferredoxin + H2O. GO:0004506 squalene monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004506 Reactome:R-HSA-191299|RHEA:25282|EC:1.14.14.17|KEGG_REACTION:R02874|MetaCyc:SQUALENE-MONOOXYGENASE-RXN squalene,NADPH:oxygen oxidoreductase (2,3-epoxidizing) activity|squalene-2,3-epoxidase activity|squalene epoxidase activity|squalene oxydocyclase activity|squalene 2,3-oxidocyclase activity|squalene-2,3-epoxide cyclase activity|squalene hydroxylase activity Catalysis of the reaction: H(+) + NADPH + O(2) + squalene = (S)-2,3-epoxysqualene + H(2)O + NADP(+). GO:0004509 steroid 21-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004509 Reactome:R-HSA-193981|MetaCyc:STEROID-21-MONOOXYGENASE-RXN|EC:1.14.14.16|Reactome:R-HSA-193964|Reactome:R-HSA-5601976 steroid,hydrogen-donor:oxygen oxidoreductase (21-hydroxylating)|cytochrome P450 CYP21A1|steroid 21-hydroxylase activity|cytochrome p450 XXIA1 activity|21-hydroxylase activity Catalysis of the reaction: A C(21) steroid + [reduced NADPH--hemoprotein reductase] + O(2) = a 21-hydroxy-C(21)-steroid + [oxidized NADPH--hemoprotein reductase] + H(2)O. GO:0004508 steroid 17-alpha-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004508 Reactome:R-HSA-193068|EC:1.14.14.19|Reactome:R-HSA-9035956|Reactome:R-HSA-9035954|Reactome:R-HSA-193099|Reactome:R-HSA-193070|MetaCyc:STEROID-17-ALPHA-MONOOXYGENASE-RXN|Reactome:R-HSA-5601843|Reactome:R-HSA-193072 17alpha-hydroxylase-C17,20 lyase activity|steroid 17-alpha-hydroxylase activity|steroid 17alpha-monooxygenase activity|steroid 17-alpha-hydroxylase-C17-20 lyase activity|steroid,hydrogen-donor:oxygen oxidoreductase (17alpha-hydroxylating)|steroid 17alpha-hydroxylase activity|steroid 17alphahydroxylase/17,20 lyase activity|steroid 17-alpha-hydroxylase/17,20 lyase activity|cytochrome P450 CYP17|cytochrome P-450 (P-45017alpha,lyase)|cytochrome P45017alpha|cytochrome p450 XVIIA1 activity Catalysis of the reaction: a steroid + AH2 + O2 = a 17a-hydroxysteroid + A + H2O. GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004514 KEGG_REACTION:R03348|RHEA:12733|Reactome:R-HSA-197268|MetaCyc:QUINOPRIBOTRANS-RXN|EC:2.4.2.19 nicotinate-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase (carboxylating)|QAPRTase activity|NAD pyrophosphorylase activity|quinolinate phosphoribosyltransferase (decarboxylating) activity|quinolinic acid phosphoribosyltransferase activity|nicotinate-nucleotide pyrophosphorylase (carboxylating) activity|quinolinic phosphoribosyltransferase activity|nicotinate mononucleotide pyrophosphorylase (carboxylating) Catalysis of the reaction: CO(2) + diphosphate + nicotinate D-ribonucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + 2 H(+) + quinolinate. GO:0004513 neolactotetraosylceramide alpha-2,3-sialyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004513 RHEA:18913|MetaCyc:2.4.99.10-RXN|EC:2.4.99.10 cytidine monophosphoacetylneuraminate-neolactotetraosylceramide sialyltransferase activity|CMP-N-acetylneuraminate:neolactotetraosylceramide alpha-2,3-sialyltransferase activity|SAT-3|sialyltransferase 3 Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide = CMP + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-D-glucosylceramide. GO:0004516 nicotinate phosphoribosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004516 KEGG_REACTION:R01724|EC:6.3.4.21|RHEA:13393|Reactome:R-HSA-197186|MetaCyc:NICOTINATEPRIBOSYLTRANS-RXN niacin ribonucleotidase activity|nicotinic acid mononucleotide pyrophosphorylase activity|nicotinic acid phosphoribosyltransferase activity|nicotinate-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase activity|nicotinic acid mononucleotide glycohydrolase activity Catalysis of the reaction: diphosphate + nicotinate D-ribonucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + H(+) + nicotinate. CHEBI:77009 5-O-beta-D-mycaminosyl-20-oxotylonolide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77009 GO:0004515 nicotinate-nucleotide adenylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004515 EC:2.7.7.18|RHEA:22860|Reactome:R-HSA-197235|Reactome:R-HSA-200512|Reactome:R-HSA-200474|MetaCyc:NICONUCADENYLYLTRAN-RXN ATP:nicotinate-ribonucleotide adenylyltransferase activity|deamido-NAD(+) pyrophosphorylase activity|deamido-NAD(+) diphosphorylase activity|deamido-NAD+ pyrophosphorylase activity|NaMN-ATase activity|nicotinate mononucleotide adenylyltransferase activity|deamidonicotinamide adenine dinucleotide pyrophosphorylase activity|nicotinic acid mononucleotide adenylyltransferase|ATP:nicotinate-nucleotide adenylyltransferase activity Catalysis of the reaction: ATP + nicotinate ribonucleotide = diphosphate + deamido-NAD+. GO:0004510 tryptophan 5-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004510 RHEA:16709|MetaCyc:TRYPTOPHAN-5-MONOOXYGENASE-RXN|EC:1.14.16.4|Reactome:R-HSA-209828 tryptophan hydroxylase activity|tryptophan 5-hydroxylase activity|L-tryptophan,tetrahydrobiopterin:oxygen oxidoreductase (5-hydroxylating)|indoleacetic acid-5-hydroxylase activity|L-tryptophan hydroxylase activity Catalysis of the reaction: L-tryptophan + tetrahydrobiopterin + O2 = 5-hydroxy-L-tryptophan + 4-alpha-hydroxytetrahydrobiopterin + H2O. GO:0004512 inositol-3-phosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004512 Reactome:R-HSA-1855178|EC:5.5.1.4|KEGG_REACTION:R07324|MetaCyc:MYO-INOSITOL-1-PHOSPHATE-SYNTHASE-RXN|RHEA:10716 glucose 6-phosphate cyclase activity|glucose-6-phosphate inositol monophosphate cycloaldolase activity|glucocycloaldolase activity|inositol 1-phosphate synthatase activity|1L-myo-inositol-1-phosphate lyase (isomerizing)|inositol 1-phosphate synthetase activity|D-glucose 6-phosphate cycloaldolase activity Catalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. This reaction requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form. GO:0004511 tyrosine 3-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004511 MetaCyc:TYROSINE-3-MONOOXYGENASE-RXN|RHEA:18201|Reactome:R-HSA-209823|EC:1.14.16.2 tyrosine hydroxylase activity|L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|tyrosine 3-hydroxylase activity|L-tyrosine hydroxylase activity Catalysis of the reaction: L-tyrosine + tetrahydrobiopterin + O2 = 3,4-dihydroxy-L-phenylalanine + 4-alpha-hydroxytetrahydrobiopterin + H2O. CHEBI:137807 lithocholic acid 24-O-(beta-D-glucuronide) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137807 CHEBI:28038 5-formyl-3-hydroxy-2-methylpyridine-4-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28038 CHEBI:28037 N-acetyl-D-galactosamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28037 CHEBI:28032 4'-hydroxyacetophenone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28032 CHEBI:28031 prostaglandin E3 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28031 CHEBI:28034 beta-D-galactoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28034 CHEBI:77002 methoxyisoflavan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77002 CHEBI:77001 1-palmitoyl-2-lauroyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77001 CHEBI:77000 1-oleoyl-2-lauroyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77000 GO:0004518 nuclease activity biolink:MolecularActivity go-plus goslim_chembl|goslim_yeast|goslim_plant|goslim_drosophila|goslim_generic http://purl.obolibrary.org/obo/GO_0004518 Catalysis of the hydrolysis of ester linkages within nucleic acids. GO:0004517 nitric-oxide synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004517 Reactome:R-HSA-418436|Reactome:R-HSA-202127|MetaCyc:NITRIC-OXIDE-SYNTHASE-RXN|RHEA:19897|EC:1.14.13.39 L-arginine,NADPH:oxygen oxidoreductase (nitric-oxide-forming) activity|nitric oxide synthase activity|nitric oxide synthetase activity|NO synthase activity|endothelium-derived relaxing factor synthase activity|NADPH-diaphorase activity|nitric-oxide synthetase activity|endothelium-derived relaxation factor-forming enzyme activity Catalysis of the reaction: L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+. GO:0004519 endonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004519 Reactome:R-HSA-5358518|Reactome:R-HSA-72180|Reactome:R-HSA-5693533|Reactome:R-HSA-5358512|Reactome:R-HSA-5690990 Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks. PO:0025066 stalk biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025066 tallo de alto orden (secundario, terciario, etc) (Spanish, exact)|stipe (related)|柄 (Japanese, exact) A cardinal organ part (PO:0025001) that is elongated and sub-cylindrical to cylindrical and supports another cardinal organ part. CHEBI:77019 EC 1.10.99.* (oxidoreductases acting on diphenols and related substances as donors, other acceptors) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77019 CHEBI:28005 cyclohex-1-ene-1-carbonyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28005 CHEBI:28001 vancomycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28001 CHEBI:28000 N-acetyl-D-hexosaminide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28000 UBERON:0006003 integumentary adnexa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006003 skin adnexa|skin appendage|body hair or bristle|skin adnexal structure|adnexae cutis Anatomical structure embedded in or located in the integument that is part of the integumental system. Examples: hair, follicles, skin glands, claws, nails, feathers. UBERON:0006002 vitelline artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006002 The paired arteries that carry blood to the yolk sac from the dorsal aorta CHEBI:422 (S)-lactic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_422 UBERON:0006009 cusp of cardiac valve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006009 cardiac valve cusp|semilunar valvule|cardial valve cusp|cardiac valvule|cardiac valvular cusp The part of the heart valves that serves to seal the heart valves when closed. There are three cusps for each valve except for the mitral valve, which has only two (hence its alternate name, 'bicuspid valve'). 'Nodules' are located at the tip of the valve, to form a tighter seal[WP]. UBERON:0006008 fibrous ring of heart biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006008 annulus fibrosus cordis|fibrous ring of heart|coronary tendon|Lower's ring|aortic annulus|atrioventricular ring|anulus fibrosus cordis|anulus fibrosus of heart A ring of ribrous tissue that surrounds the atrioventricular and arterial orifices CHEBI:77011 5-O-mycaminosyltylonolide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77011 PO:0025059 portion of ground tissue biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025059 基本組織の一部 (Japanese, exact)|porción del tejido fundamental (Spanish, exact)|fundamental tissue (exact) Any portion of plant tissue (PO:0009007) other than epidermis (PO:0005679) or vascular tissue (PO:0009015). CHEBI:77016 (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77016 CHEBI:77015 (4Z,7Z,10Z,13Z,16Z,19Z)-22-hydroxydocosahexaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77015 CHEBI:28018 3,3',4',5,7-pentahydroxy-8-methoxyflavone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28018 CHEBI:28017 starch biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28017 CHEBI:28013 beta-D-fructofuranose 1,6-bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28013 CHEBI:28011 2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28011 CHEBI:77021 cellobionic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77021 CHEBI:77020 EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77020 CHEBI:77024 EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77024 PO:0001097 plant zygote stage biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0001097 zygote in Arabidopsis (related)|one cell stage (related)|zygote stage (broad)|embryo stage EM1 (related) A sporophyte development stage (PO:0007134) that occurs during the interval between fertilization and the first cell division of the plant zygote (PO:0000423). CHEBI:77029 3-(5-oxoisoxazolin-2-yl)-L-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77029 CHEBI:77027 7-deoxyloganetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77027 CHEBI:77031 (2S,3S)-beta-methylphenylalanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77031 CHEBI:77030 3-(5-oxoisoxazolin-4-yl)-L-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77030 CHEBI:77036 A41030A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77036 CHEBI:77035 expectorant biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77035 CHEBI:77034 mucolytic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77034 CHEBI:18697 (R)-pantoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18697 CHEBI:77033 14-hydroxymyristate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77033 PO:0001083 inflorescence development stage biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0001083 panicle development (related) A reproductive shoot system development stage (PO:0025530) that has as primary participant a inflorescence (PO:0009049). CHEBI:77039 (2E)-tetradecenedioyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77039 CHEBI:77038 (3S)-hydroxytetradecanedioyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77038 CHEBI:77037 N,N-dimethyl-L-alanyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77037 PO:0025034 leaf biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025034 hoja (Spanish, exact)|葉 (Japanese, exact) A phyllome (PO:0006001) that is not associated with a reproductive structure. PO:0025030 ground tissue cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025030 基本組織細胞 (Japanese, exact)|célula del tejido fundamental (Spanish, exact)|fundamental tissue cell (exact) A native plant cell (PO:0025606) that is part of a portion of ground tissue (PO:0025059). CHEBI:43619 icosane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_43619 CHEBI:43615 2H-imidazol-4-ylacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_43615 CHEBI:77042 N,N-dimethyl-L-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77042 CHEBI:77041 3-oxotetradecanedioyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77041 CHEBI:77047 tylosin(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77047 CHEBI:77046 isopimarane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77046 PO:0025029 shoot axis biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025029 caullome (exact)|shoot (related)|eje del epiblasto (epiblastema) (Spanish, exact)|シュート軸 (Japanese, exact) A plant axis (PO:0025004) that is part of a shoot system (PO:0009006). PO:0025028 embryo plant cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025028 embryo cell (broad)|embryonic plant cell (exact)|胚性植物細胞 (Japanese, exact)|célula embriónica vegetal (Spanish, exact)|embryonic cell (broad) A native plant cell (PO:0025606) that is part of a plant embryo (PO:0009009). PO:0025026 embryo sac cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025026 embryo sac cell (related)|célula megagametofítica (Spanish, exact)|胚嚢細胞 (Japanese, exact)|megagametophytic cell (exact) A native plant cell (PO:0025606) that is part of an embryo sac (PO:0025074). CHEBI:77049 (R,R)-pavine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77049 PO:0025025 root system biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025025 根系 (Japanese, exact)|sistema de raíz (Spanish, exact)|root (broad) A collective plant organ structure (PO:0025007) that produces root meristems (PO:0006085), the plant structures (PO:0009011) that arise from them and the parts thereof. CHEBI:77048 pavine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77048 CHEBI:137899 phosphatidic acid 44:6 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137899 CHEBI:137898 phosphatidic acid 43:5 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137898 CHEBI:53082 prostaglandin H2 1-ethanolamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_53082 CHEBI:137897 phosphatidic acid 41:5 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137897 CHEBI:137896 phosphatidic acid 41:3 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137896 CHEBI:53081 prostaglandin F2alpha 1-ethanolamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_53081 CHEBI:137891 phosphatidic acid 39:1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137891 CHEBI:137890 phosphatidic acid 38:0 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137890 CHEBI:137895 phosphatidic acid 41:2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137895 CHEBI:137894 phosphatidic acid 41:1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137894 CHEBI:137893 phosphatidic acid 40:2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137893 CHEBI:137892 phosphatidic acid 39:2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137892 CHEBI:53072 beta-L-galactose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53072 CHEBI:53071 L-galactonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_53071 CHEBI:53079 lysine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53079 GO:0004587 ornithine-oxo-acid transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004587 Reactome:R-HSA-70654|MetaCyc:ORNITHINE--OXO-ACID-AMINOTRANSFERASE-RXN|EC:2.6.1.13|RHEA:13877|Reactome:R-HSA-70666 L-ornithine:alpha-ketoglutarate delta-aminotransferase activity|ornithine 5-aminotransferase activity|L-ornithine 5-aminotransferase activity|ornithine aminotransferase activity|L-ornithine aminotransferase activity|L-ornithine:2-oxo-acid aminotransferase activity|ornithine--alpha-ketoglutarate aminotransferase activity|ornithine--keto acid transaminase activity|ornithine delta-transaminase activity|GabT|ornithine-oxo-acid aminotransferase activity|ornithine--oxo acid aminotransferase activity|ornithine ketoacid aminotransferase activity|ornithine:alpha-oxoglutarate transaminase activity|ornithine--oxo-acid transaminase activity|ornithine transaminase activity|OAT|ornithine--2-oxoacid aminotransferase activity|ornithine--keto acid aminotransferase activity|ornithine--ketoglutarate aminotransferase activity Catalysis of the reaction: L-ornithine + a 2-oxo acid = L-glutamate 5-semialdehyde + an L-amino acid. GO:0004586 ornithine decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004586 EC:4.1.1.17|Reactome:R-HSA-70692|RHEA:22964|MetaCyc:ORNDECARBOX-RXN|KEGG_REACTION:R00670 SpeC|L-ornithine carboxy-lyase (putrescine-forming)|L-ornithine carboxy-lyase activity Catalysis of the reaction: L-ornithine + H(+) = CO(2) + putrescine. GO:0004589 orotate reductase (NADH) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004589 MetaCyc:OROTATE-REDUCTASE-NADH-RXN|KEGG_REACTION:R01869|EC:1.3.1.14|RHEA:13513 (S)-dihydroorotate:NAD+ oxidoreductase activity Catalysis of the reaction: (S)-dihydroorotate + NAD(+) = H(+) + NADH + orotate. GO:0004588 orotate phosphoribosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004588 Reactome:R-HSA-73567|MetaCyc:OROPRIBTRANS-RXN|EC:2.4.2.10|RHEA:10380 orotidylic acid phosphorylase activity|orotidine-5'-phosphate pyrophosphorylase activity|orotidine-5'-phosphate diphosphorylase activity|orotidylic phosphorylase activity|orotidine monophosphate pyrophosphorylase activity|orotic acid phosphoribosyltransferase activity|orotidylate phosphoribosyltransferase activity|orotate phosphoribosyl pyrophosphate transferase activity|orotidine phosphoribosyltransferase activity|orotidylate pyrophosphorylase activity|OPRT activity|orotidine-5'-phosphate:diphosphate phospho-alpha-D-ribosyl-transferase activity|orotidine 5'-monophosphate pyrophosphorylase activity|OPRTase activity|orotidylic acid pyrophosphorylase activity|orotidylic pyrophosphorylase activity Catalysis of the reaction: orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate. GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004583 Reactome:R-HSA-446194|MetaCyc:RXN-5472|Reactome:R-HSA-4724330|Reactome:R-HSA-4724291|Reactome:R-HSA-446202|Reactome:R-HSA-446189 Catalysis of the transfer of an alpha-D-glucosyl residue from dolichyl-phosphate D-glucose into a membrane lipid-linked oligosaccharide. GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004582 Reactome:R-HSA-4719375|Reactome:R-HSA-4719354|EC:2.4.1.83|RHEA:21184|Reactome:R-HSA-162721|Reactome:R-HSA-4717406|MetaCyc:2.4.1.83-RXN DPM synthase activity|dolichyl-phosphate mannose synthase activity|dolichyl phosphate mannosyltransferase activity|guanosine diphosphomannose-dolichol phosphate mannosyltransferase activity|mannosylphosphodolichol synthase activity|dolichol-phosphate-mannose synthase activity|GDPMan:DolP mannosyltransferase activity|GDP-mannose:dolichyl-phosphate beta-D-mannosyltransferase activity|GDP-mannose-dolichol phosphate mannosyltransferase activity|dolichol phosphate mannose synthase activity|GDPmannose-dolichylmonophosphate mannosyltransferase activity|dolichyl-phospho-mannose synthase activity|GDPmannose:dolichyl-phosphate mannosyltransferase activity|dolichyl mannosyl phosphate synthase activity|dolichol-phosphate mannose synthase activity|mannosylphosphoryldolichol synthase activity|dolichol-phosphate mannosyltransferase activity Catalysis of the reaction: GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate. GO:0004585 ornithine carbamoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004585 MetaCyc:RXN-13482|Reactome:R-HSA-70560|RHEA:19513|EC:2.1.3.3|MetaCyc:ORNCARBAMTRANSFER-RXN L-ornithine carbamyltransferase activity|ornithine carbamyltransferase activity|carbamylphosphate-ornithine transcarbamylase activity|ornithine transcarbamylase activity|L-ornithine transcarbamylase activity|L-ornithine carbamoyltransferase activity|carbamoyl-phosphate:L-ornithine carbamoyltransferase activity|OTCase activity|citrulline phosphorylase activity|OTC activity Catalysis of the reaction: carbamoyl phosphate + L-ornithine = phosphate + L-citrulline. GO:0004584 obsolete dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004584 MetaCyc:2.4.1.130-RXN|EC:2.4.1.130 dolichyl-phosphate-D-mannose:glycolipid alpha-D-mannosyltransferase activity|dolichol phosphomannose-oligosaccharide-lipid mannosyltransferase activity|oligomannosylsynthase activity OBSOLETE. Catalysis of the transfer of an alpha-D-mannosyl residue from dolichyl-phosphate D-mannose into membrane lipid-linked oligosaccharide. GO:0004581 dolichyl-phosphate beta-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004581 MetaCyc:2.4.1.117-RXN|RHEA:15401|EC:2.4.1.117|Reactome:R-HSA-446214 UDP-glucose:dolichol phosphate glucosyltransferase activity|uridine diphosphoglucose-dolichol glucosyltransferase activity|polyprenyl phosphate:UDP-D-glucose glucosyltransferase activity|UDP-glucose:dolicholphosphoryl glucosyltransferase activity|UDP-glucose dolichyl-phosphate glucosyltransferase activity|UDP-glucose:dolichyl-phosphate beta-D-glucosyltransferase activity|UDP-glucose:dolichyl monophosphate glucosyltransferase activity|UDP-glucose:dolichyl phosphate glucosyltransferase activity|UDPglucose:dolichyl-phosphate beta-D-glucosyltransferase activity Catalysis of the reaction: UDP-glucose + dolichyl phosphate = UDP + dolichyl beta-D-glucosyl phosphate. GO:0004580 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004580 GO:0004598 peptidylamidoglycolate lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004598 EC:4.3.2.5|RHEA:20924|MetaCyc:PEPTIDYLAMIDOGLYCOLATE-LYASE-RXN HGAD|peptidyl-alpha-hydroxyglycine alpha-amidating lyase activity|PAL|peptidylamidoglycolate peptidylamide-lyase activity|peptidylamidoglycolate peptidylamide-lyase (glyoxylate-forming)|PGL|alpha-hydroxyglycine amidating dealkylase activity Catalysis of the reaction: peptidylamidoglycolate = peptidyl amide + glyoxylate. GO:0004597 peptide-aspartate beta-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004597 EC:1.14.11.16|MetaCyc:PEPTIDE-ASPARTATE-BETA-DIOXYGENASE-RXN aspartylpeptide beta-dioxygenase activity|peptide-L-aspartate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity|aspartyl/asparaginyl beta-hydroxylase activity|aspartate beta-hydroxylase activity Catalysis of the reaction: peptide L-aspartate + 2-oxoglutarate + O2 = peptide 3-hydroxy-L-aspartate + succinate + CO2. GO:0004594 pantothenate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004594 RHEA:16373|Reactome:R-HSA-199203|Reactome:R-HSA-196857|MetaCyc:PANTOTHENATE-KIN-RXN|EC:2.7.1.33 ATP:(R)-pantothenate 4'-phosphotransferase activity|pantothenate kinase (phosphorylating) activity|pantothenic acid kinase activity|D-pantothenate kinase activity|ATP:pantothenate 4'-phosphotransferase activity Catalysis of the reaction: ATP + pantothenate = ADP + D-4'-phosphopantothenate. GO:0004593 pantothenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004593 RHEA:12448|EC:3.5.1.22|MetaCyc:PANTOTHENASE-RXN|KEGG_REACTION:R02474 pantothenate amidohydrolase activity|pantothenate hydrolase activity|(R)-pantothenate amidohydrolase activity Catalysis of the reaction: (R)-pantothenate + H(2)O = (R)-pantoate + beta-alanine. GO:0004596 peptide alpha-N-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004596 Reactome:R-HSA-6814090|MetaCyc:PEPTIDE-ALPHA-N-ACETYLTRANSFERASE-RXN nalpha-acetyltransferase activity|amino-terminal amino acid-acetylating enzyme activity|acetyl-CoA:peptide alpha-N-acetyltransferase activity|peptide acetyltransferase activity|protein N-terminal acetyltransferase activity|beta-endorphin acetyltransferase activity|N(alpha)-acetyltransferase activity|acetyl-CoA:peptide nalpha-acetyltransferase activity|NAT activity Catalysis of the reaction: acetyl-CoA + peptide = CoA + N-alpha-acetylpeptide. This reaction is the acetylation of the N-terminal amino acid residue of a peptide or protein. GO:0004595 pantetheine-phosphate adenylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004595 Reactome:R-HSA-196754|EC:2.7.7.3|MetaCyc:PANTEPADENYLYLTRAN-RXN|KEGG_REACTION:R03035|RHEA:19801 ATP:pantetheine-4'-phosphate adenylyltransferase activity|ATP:pantetheine-phosphate adenylyltransferase activity|3'-dephospho-CoA pyrophosphorylase activity|pantetheine phosphate adenylyltransferase activity|PPAT activity|phosphopantetheine adenylyltransferase activity|dephospho-coenzyme A pyrophosphorylase activity|dephospho-CoA pyrophosphorylase activity|dephospho-CoA diphosphorylase activity Catalysis of the reaction: ATP + pantetheine 4'-phosphate = 3'-dephospho-CoA + diphosphate. GO:0004590 orotidine-5'-phosphate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004590 MetaCyc:OROTPDECARB-RXN|Reactome:R-HSA-73564|KEGG_REACTION:R00965|EC:4.1.1.23|RHEA:11596 ODCase activity|orotodylate decarboxylase activity|orotic decarboxylase activity|orotate monophosphate decarboxylase activity|orotidine 5'-phosphate decarboxylase activity|orotidine-5'-phosphate carboxy-lyase activity|orotate decarboxylase activity|OMP-DC|orotidylic acid decarboxylase activity|orotidine-5'-monophosphate decarboxylase activity|orotidylic decarboxylase activity|orotidine-5'-phosphate carboxy-lyase (UMP-forming)|OMP decarboxylase activity|UMP synthase activity|uridine 5'-monophosphate synthase activity|orotidine monophosphate decarboxylase activity|OMPdcase activity|orotidine phosphate decarboxylase activity Catalysis of the reaction: H(+) + orotidine 5'-phosphate = CO(2) + UMP. GO:0004592 pantoate-beta-alanine ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004592 MetaCyc:PANTOATE-BETA-ALANINE-LIG-RXN|RHEA:10912|EC:6.3.2.1 pantoic-activating enzyme activity|pantoate-activating enzyme activity|(R)-pantoate:beta-alanine ligase (AMP-forming)|pantothenate synthetase activity|D-pantoate:beta-alanine ligase (AMP-forming) Catalysis of the reaction: ATP + (R)-pantoate + beta-alanine = AMP + diphosphate + (R)-pantothenate. GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004591 EC:1.2.4.2|MetaCyc:2OXOGLUTDECARB-RXN|RHEA:12188 2-oxoglutarate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-succinylating) activity|2-oxoglutarate: lipoate oxidoreductase activity|ketoglutaric dehydrogenase activity|OGDC activity|alpha-oxoglutarate dehydrogenase activity|2-oxoglutarate:dihydrolipoyllysine-residue succinyltransferase-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-succinylating)|alpha-ketoglutaric acid dehydrogenase activity|oxoglutarate decarboxylase activity|2-ketoglutarate dehydrogenase activity|AKGDH activity|oxoglutarate dehydrogenase (lipoamide) activity|2-oxoglutarate dehydrogenase activity|alpha-ketoglutaric dehydrogenase activity|oxoglutarate dehydrogenase activity|alpha-ketoglutarate dehydrogenase activity Catalysis of the reaction: 2-oxoglutarate + lipoamide = S-succinyldihydrolipoamide + CO2. CHEBI:137886 3alpha,7beta-dihydroxy-12-oxo-5beta-cholanate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137886 CHEBI:137880 ursocholate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137880 CHEBI:137882 7beta-hydroxy-3,12-dioxo-5beta-cholanate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137882 CHEBI:137881 3,7,12-trioxo-5beta-cholan-24-oate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137881 GO:0004569 glycoprotein endo-alpha-1,2-mannosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004569 EC:3.2.1.130|RHEA:54824|Reactome:R-HSA-964759|MetaCyc:3.2.1.130-RXN glycoprotein glucosylmannohydrolase activity|glucosyl mannosidase activity|endomannosidase activity|glucosylmannosidase activity|endo-alpha-mannosidase activity Catalysis of the hydrolysis of the terminal alpha-glucosyl-(1,3)-mannosyl unit from Glc-Man(9)-(GlcNAc)(2) oligosaccharide component of the glycoprotein produced in the Golgi membrane. GO:0004568 chitinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004568 EC:3.2.1.14|Reactome:R-HSA-6786421|MetaCyc:3.2.1.14-RXN poly[1,4-(N-acetyl-beta-D-glucosaminide)] glycanohydrolase activity|poly-beta-glucosaminidase activity|1,4-beta-poly-N-acetylglucosaminidase activity|chitodextrinase activity|beta-1,4-poly-N-acetyl glucosamidinase activity Catalysis of the hydrolysis of (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. GO:0004565 beta-galactosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004565 MetaCyc:BGALACT-PWY|Reactome:R-HSA-9036061|EC:3.2.1.23|Reactome:R-HSA-2265534|Reactome:R-HSA-1630306|Reactome:R-HSA-1605624|Reactome:R-HSA-1793217|MetaCyc:3.2.1.23-RXN|Reactome:R-HSA-1606312|Reactome:R-HSA-2090079 exo-(1->4)-beta-D-galactanase activity|beta-lactosidase activity|hydrolact|S 2107|sumiklat|beta-D-galactanase activity|trilactase activity|maxilact|oryzatym|beta-D-galactoside galactohydrolase activity|beta-D-lactosidase activity|lactozym|lactose hydrolysis Catalysis of the hydrolysis of terminal, non-reducing beta-D-galactose residues in beta-D-galactosides. GO:0004564 beta-fructofuranosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004564 MetaCyc:RXN-9985|EC:3.2.1.26 beta-D-fructofuranoside fructohydrolase activity|beta-fructosidase activity|alkaline invertase activity|maxinvert L 1000 activity|beta-h-fructosidase activity|acid invertase activity|invertin activity|invertase activity|glucosucrase activity|saccharase activity|fructosylinvertase activity Catalysis of the reaction: a fructofuranosylated fructofuranosyl acceptor + H2O = a non fructofuranosylated fructofuranosyl acceptor + a beta-D-fructofuranoside. GO:0004567 beta-mannosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004567 Reactome:R-HSA-8853710|EC:3.2.1.25|MetaCyc:3.2.1.25-RXN beta-D-mannoside mannohydrolase activity|mannanase activity|beta-D-mannosidase activity|exo-beta-D-mannanase activity|mannase activity|beta-mannoside mannohydrolase activity Catalysis of the hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-mannosides. GO:0004566 beta-glucuronidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004566 Reactome:R-HSA-2162226|Reactome:R-HSA-9036070|MetaCyc:BETA-GLUCURONID-RXN|EC:3.2.1.31|Reactome:R-HSA-9036068|RHEA:17633|Reactome:R-HSA-2162227|Reactome:R-HSA-2318373|Reactome:R-HSA-1678854 exo-beta-D-glucuronidase activity|beta-glucuronide glucuronohydrolase activity|ketodase activity|glucuronidase activity|beta-D-glucuronoside glucuronosohydrolase activity Catalysis of the reaction: a beta-D-glucuronoside + H2O = an alcohol + D-glucuronate. GO:0004561 alpha-N-acetylglucosaminidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004561 EC:3.2.1.50|Reactome:R-HSA-1678742|Reactome:R-HSA-9036052|Reactome:R-HSA-2090038|Reactome:R-HSA-2263496|MetaCyc:3.2.1.50-RXN alpha-N-acetyl-D-glucosaminide N-acetylglucosaminohydrolase activity|alpha-D-2-acetamido-2-deoxyglucosidase activity|N-acetyl-alpha-glucosaminidase activity|alpha-acetylglucosaminidase activity|N-acetyl-alpha-D-glucosaminidase activity|NAG activity Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides. GO:0004560 alpha-L-fucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004560 EC:3.2.1.51|RHEA:12288|Reactome:R-HSA-5693807|MetaCyc:ALPHA-L-FUCOSIDASE-RXN alpha-L-fucoside fucohydrolase activity|alpha-fucosidase activity Catalysis of the reaction: an alpha-L-fucoside + H2O = an alcohol + L-fucose. GO:0004563 beta-N-acetylhexosaminidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004563 Reactome:R-HSA-3656259|Reactome:R-HSA-1605595|Reactome:R-HSA-9638078|Reactome:R-HSA-2105001|Reactome:R-HSA-1605632|Reactome:R-HSA-9638075|Reactome:R-HSA-9035982|Reactome:R-HSA-9638076|EC:3.2.1.52|Reactome:R-HSA-1638053|Reactome:R-HSA-9035978|Reactome:R-HSA-9035983|Reactome:R-HSA-9035976|Reactome:R-HSA-2162225|MetaCyc:3.2.1.52-RXN|Reactome:R-HSA-3662344 N-acetyl-beta-hexosaminidase activity|N-acetyl-beta-glucosaminidase activity|beta-N-acetyl-D-hexosaminidase activity|beta-acetylhexosaminidinase activity|N-acetyl-beta-D-hexosaminidase activity|beta-hexosaminidase activity|beta-N-acetyl-D-hexosaminide N-acetylhexosaminohydrolase activity|hexosaminidase A|beta-acetylaminodeoxyhexosidase activity|N-acetylhexosaminidase activity|beta-D-hexosaminidase activity|beta-D-N-acetylhexosaminidase activity Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides. GO:0004562 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004562 CHEBI:28087 glycogen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28087 CHEBI:28089 N-hydroxytyrosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28089 CHEBI:28088 genistein biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28088 CHEBI:28093 borneol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28093 CHEBI:53041 dodecaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53041 CHEBI:28096 S-methyl-5-thio-D-ribulose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28096 CHEBI:137852 phosphatidylcholine 14:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137852 CHEBI:53040 tridecaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53040 CHEBI:137856 5alpha-dihydrotestosterone 17-O-[beta-D-glucuronosyl-(1->2)-glucuronide] biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137856 CHEBI:53047 hexaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53047 CHEBI:53046 heptaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53046 CHEBI:53048 pentaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53048 CHEBI:53043 decaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53043 CHEBI:53042 undecaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53042 CHEBI:53045 octaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53045 CHEBI:53044 nonaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53044 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004579 RHEA:22980|EC:2.4.99.18|Reactome:R-HSA-9694793|Reactome:R-HSA-446209|MetaCyc:2.4.1.119-RXN dolichyl-diphosphooligosaccharide-protein glycosyltransferase activity|oligomannosyltransferase activity|asparagine N-glycosyltransferase activity|dolichyldiphosphooligosaccharide-protein oligosaccharyltransferase activity|dolichylpyrophosphodiacetylchitobiose-protein glycosyltransferase activity|dolichyldiphosphooligosaccharide-protein glycosyltransferase activity|dolichyldiphosphoryloligosaccharide-protein oligosaccharyltransferase activity|dolichyl-diphosphooligosaccharide:protein-L-asparagine oligopolysaccharidotransferase activity Catalysis of the reaction: dolichyl diphosphooligosaccharide + protein L-asparagine = dolichyl diphosphate + a glycoprotein with the oligosaccharide chain attached by glycosylamine linkage to protein L-asparagine. GO:0004576 oligosaccharyl transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004576 oligosaccharide transferase activity Catalysis of the transfer of a oligosaccharyl group to an acceptor molecule, typically another carbohydrate or a lipid. GO:0004575 sucrose alpha-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004575 Reactome:R-HSA-189069|Reactome:R-HSA-5659926|MetaCyc:RXN-1461|EC:3.2.1.48|KEGG_REACTION:R00802|RHEA:33795 sucrose alpha-D-glucohydrolase activity|sucrase-isomaltase activity|sucrase(invertase)|sucrase activity|sucrose hydrolysis|intestinal sucrase activity|alpha-D-glucopyranosyl beta-D-fructofuranoside hydrolysis|sucrose-alpha-D-glucohydrolase activity|beta-D-fructofuranosyl alpha-D-glucopyranoside hydrolysis|sucrose alpha-glucohydrolase activity Catalysis of the reaction: sucrose + H2O = alpha-D-glucose + beta-D-fructose. CHEBI:53039 tetradecaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53039 GO:0004578 chitobiosyldiphosphodolichol beta-mannosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004578 Reactome:R-HSA-446218|MetaCyc:2.4.1.142-RXN|Reactome:R-HSA-4549382|EC:2.4.1.142|RHEA:13865 guanosine diphosphomannose-dolichol diphosphochitobiose mannosyltransferase activity|GDP-mannose-dolichol diphosphochitobiose mannosyltransferase activity|GDP-mannose:chitobiosyldiphosphodolichol beta-D-mannosyltransferase activity Catalysis of the reaction: GDP-mannose + chitobiosyldiphosphodolichol = GDP + beta-D-mannosylchitobiosyldiphosphodolichol. GO:0004577 N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004577 MetaCyc:2.4.1.141-RXN|RHEA:23380|EC:2.4.1.141|Reactome:R-HSA-446207|Reactome:R-HSA-5633241 UDP-GlcNAc:dolichyl-pyrophosphoryl-GlcNAc GlcNAc transferase activity|UDP-N-acetyl-D-glucosamine:N-acetyl-D-glucosaminyl-diphosphodolichol N-acetyl-D-glucosaminyltransferase activity|N,N'-diacetylchitobiosylpyrophosphoryldolichol synthase activity|uridine diphosphoacetylglucosamine-dolichylacetylglucosamine pyrophosphate acetylglucosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + N-acetyl-D-glucosaminyl-diphosphodolichol = UDP + N,N''-diacetylchitobiosyldiphosphodolichol. GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004572 MetaCyc:3.2.1.114-RXN|EC:3.2.1.114|RHEA:56052|Reactome:R-HSA-975814 ManII activity|GlcNAc transferase I-dependent alpha1,3[alpha1,6]mannosidase activity|mannosidase II activity|alpha-(1,3/6)-mannosidase activity|alpha-D-mannosidase II|exo-1,3-1,6-alpha-mannosidase activity|1,3-(1,6-)mannosyl-oligosaccharide alpha-D-mannohydrolase activity|alpha-mannosidase II|mannosyl-oligosaccharide (1->3,6)-alpha-mannosidase activity|mannosyl-oligosaccharide (1->3/6)-alpha-mannosidase activity|Golgi alpha-mannosidase II|mannosyl-oligosaccharide (1->3)-(1->6)-alpha-mannosidase activity Catalysis of the hydrolysis of the terminal (1->3)- and (1->6)-linked alpha-D-mannose residues in the mannosyl-oligosaccharide Man(5)(GlcNAc)(3). GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004571 Reactome:R-HSA-901039|MetaCyc:3.2.1.113-RXN|KEGG_REACTION:R05982|Reactome:R-HSA-901024|EC:3.2.1.113|Reactome:R-HSA-9696807|Reactome:R-HSA-9036012|Reactome:R-HSA-9036011|Reactome:R-HSA-6782685|Reactome:R-HSA-964825|Reactome:R-HSA-964737|Reactome:R-HSA-964830|Reactome:R-HSA-901036|Reactome:R-HSA-9036008|KEGG_REACTION:R06722|Reactome:R-HSA-901074|Reactome:R-HSA-4793949 1,2-alpha-mannosidase|glycoprotein processing mannosidase I|exo-alpha-1,2-mannanase activity|1,2-alpha-mannosyl-oligosaccharide alpha-D-mannohydrolase activity|mannose-9 processing alpha-mannosidase activity|ManI activity|mannosidase 1A activity|mannosidase I|mannosidase 1B activity|Man9-mannosidase activity|man9-mannosidase activity Catalysis of the hydrolysis of the terminal (1->2)-linked alpha-D-mannose residues in an oligo-mannose oligosaccharide. GO:0004574 oligo-1,6-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004574 MetaCyc:3.2.1.10-RXN|EC:3.2.1.10 exo-oligo-1,6-glucosidase activity|dextrin 6-glucanohydrolase activity|dextrin 6alpha-glucanohydrolase activity|oligosaccharide alpha-1,6-glucohydrolase activity|alpha-limit dextrinase activity|isomaltase activity|oligosaccharide alpha-1,6-glucosidase activity|alpha-methylglucosidase activity|limit dextrinase|sucrase-isomaltase activity Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in some oligosaccharides produced from starch and glycogen by alpha-amylase, and in isomaltose. Releases a free alpha-D-glucose. GO:0004573 mannosyl-oligosaccharide glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004573 EC:3.2.1.106|Reactome:R-HSA-9694364|RHEA:55988|Reactome:R-HSA-532678|Reactome:R-HSA-4793947|MetaCyc:3.2.1.106-RXN Glc3Man9NAc2 oligosaccharide glucosidase activity|mannosyl-oligosaccharide glucohydrolase activity|trimming glucosidase I|processing A-glucosidase I activity|mannosyl-oligosaccharide glucosidase (processing A-glucosidase I) activity Catalysis of the exohydrolysis of the non-reducing terminal glucose residue in the mannosyl-oligosaccharide Glc(3)Man(9)GlcNAc(2). CHEBI:28098 kanamycin B biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28098 CHEBI:28097 chlorobenzene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28097 CHEBI:28099 prostaglandin B2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28099 CHEBI:53030 oxysterol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53030 GO:0004549 tRNA-specific ribonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004549 Reactome:R-HSA-5696813|Reactome:R-HSA-6785722|Reactome:R-HSA-6786854|Reactome:R-HSA-5696815 tRNA-specific RNase activity Catalysis of the hydrolysis of phosphodiester bonds in tRNA molecules. CHEBI:53028 4-deoxy-4-formamido-alpha-L-arabinopyranosyl ditrans,polycis-undecaprenyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53028 CHEBI:28068 all-trans-zeta-carotene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28068 GO:0004540 ribonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004540 Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA. CHEBI:28064 cyanidin 3-O-rutinoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28064 CHEBI:28066 gentiobiose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28066 CHEBI:28072 guanosine 3'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28072 CHEBI:28071 (indol-3-ylacetyl)-myo-inositol 3-L-arabinoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28071 CHEBI:28073 chromium atom biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28073 CHEBI:137837 2-hydroxy-17beta-estradiol 3-O-(beta-D-glucuronide) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137837 CHEBI:137836 alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(36:1) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137836 CHEBI:28070 uridine 2'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28070 CHEBI:53025 L-galactose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53025 GO:0004558 alpha-1,4-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004558 Reactome:R-HSA-5659899|EC:3.2.1.20|Reactome:R-HSA-191116|MetaCyc:MALTODEXGLUCOSID-RXN|Reactome:R-HSA-189102|Reactome:R-HSA-191108|Reactome:R-HSA-5659922|Reactome:R-HSA-5659861|Reactome:R-HSA-189053|Reactome:R-HSA-5659879|Reactome:R-HSA-191101 alpha-1,4-glucosidase activity|glucosidoinvertase activity|alpha-D-glucoside glucohydrolase activity|glucoinvertase activity|alpha-glucosidase II|glucosidosucrase activity|alpha-D-glucosidase activity|alpha-glucopyranosidase activity|lysosomal alpha-glucosidase activity|maltase-glucoamylase activity|acid maltase activity|alpha-glucoside hydrolase activity Catalysis of the hydrolysis of terminal, non-reducing alpha-(1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose. GO:0004557 alpha-galactosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004557 MetaCyc:ALPHAGALACTOSID-RXN|RHEA:28663|Reactome:R-HSA-1605736|EC:3.2.1.22 alpha-D-galactosidase activity|alpha-galactosidase A|alpha-galactoside galactohydrolase activity|melibiase activity|alpha-D-galactoside galactohydrolase activity Catalysis of the hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactohydrolase. GO:0004559 alpha-mannosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004559 Reactome:R-HSA-6799545|MetaCyc:3.2.1.24-RXN|Reactome:R-HSA-8853686|Reactome:R-HSA-9694656|EC:3.2.1.24 exo-alpha-mannosidase activity|alpha-D-mannopyranosidase activity|alpha-D-mannoside mannohydrolase activity|p-nitrophenyl-alpha-mannosidase activity|1,2-alpha-D-mannosidase activity|alpha-D-mannosidase activity|1,2-alpha-mannosidase Catalysis of the hydrolysis of terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides. GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004553 Reactome:R-HSA-9661820|EC:3.2.1.-|Reactome:R-HSA-5694563|Reactome:R-HSA-6786652 O-glucosyl hydrolase activity Catalysis of the hydrolysis of any O-glycosyl bond. GO:0004556 alpha-amylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004556 Reactome:R-HSA-188979|MetaCyc:RXN-1825|EC:3.2.1.1|MetaCyc:RXN-1823|MetaCyc:ALPHA-AMYL-RXN|Reactome:R-HSA-191114 alpha amylase activity|1,4-alpha-D-glucan glucanohydrolase activity|endoamylase activity|taka-amylase A|glycogenase activity Catalysis of the endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more alpha-(1->4)-linked D-glucose units. GO:0004555 alpha,alpha-trehalase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004555 Reactome:R-HSA-188985|MetaCyc:TREHALA-RXN|EC:3.2.1.28|RHEA:20868 alpha,alpha-trehalose glucohydrolase activity Catalysis of the reaction: alpha,alpha-trehalose + H2O = 2 D-glucose. GO:0004550 nucleoside diphosphate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004550 Reactome:R-HSA-2162096|Reactome:R-HSA-482812|Reactome:R-HSA-6806877|MetaCyc:NUCLEOSIDE-DIP-KIN-RXN|Reactome:R-HSA-482619|Reactome:R-HSA-482621|Reactome:R-HSA-482804|EC:2.7.4.6 UDP kinase activity|uridine diphosphate kinase activity|nucleoside-diphosphate kinase activity|nucleoside diphosphate (UDP) kinase activity|nucleoside diphosphokinase activity|ATP:nucleoside-diphosphate phosphotransferase activity|NDK activity|nucleotide phosphate kinase activity|nucleoside 5'-diphosphate kinase activity|nucleoside 5'-diphosphate phosphotransferase activity Catalysis of the reaction: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate. GO:0004552 octanol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004552 RHEA:24620|MetaCyc:OCTANOL-DEHYDROGENASE-RXN|KEGG_REACTION:R02878|EC:1.1.1.73 1-octanol dehydrogenase activity|octanol:NAD+ oxidoreductase activity Catalysis of the reaction: 1-octanol + NAD(+) = 1-octanal + H(+) + NADH. GO:0004551 nucleotide diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004551 Reactome:R-HSA-196955|MetaCyc:NUCLEOTIDE-PYROPHOSPHATASE-RXN|EC:3.6.1.9 dinucleotide nucleotidohydrolase activity|nucleotide pyrophosphatase activity|nucleotide-sugar pyrophosphatase activity Catalysis of the reaction: a dinucleotide + H2O = 2 mononucleotides. CHEBI:137849 phosphatidic acid 32:5 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137849 CHEBI:28077 rifampicin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28077 CHEBI:28082 5alpha-cholestane-3beta,5,6beta-triol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28082 CHEBI:7815 oxalosuccinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_7815 CHEBI:28080 (2Z,4E)-2-hydroxymuconate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28080 CHEBI:53013 3'-CMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53013 CHEBI:53010 nucleoside 2'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53010 CHEBI:53012 xanthosine 5'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53012 GO:0102991 myristoyl-CoA hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102991 EC:3.1.2.2|MetaCyc:RXN-9626|RHEA:40119 Catalysis of the reaction: myristoyl-CoA + H2O <=> H+ + tetradecanoate + coenzyme A. GO:0102990 5-n-alk(en)ylresorcinol O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102990 RHEA:26325|MetaCyc:RXN-9619 Catalysis of the reaction: 5-(pentadeca-8,11,14-trien-1-yl)resorcinol + S-adenosyl-L-methionine <=> H+ + 5-(pentadeca-8,11,14-trien-1-yl)resorcinol monomethyl ether + S-adenosyl-L-homocysteine. GO:0102993 linolenate Delta15 desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102993 MetaCyc:RXN-9667|RHEA:46408 Catalysis of the reaction: O2 + a lipid linoleoyl group + a reduced electron acceptor <=> 2 H2O + a lipid alpha-linolenoyl group + an oxidized electron acceptor. GO:0102992 2-methylbutyronitrile hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102992 RHEA:51948|MetaCyc:RXN-9642 Catalysis of the reaction: H+ + 2-methylbutyronitrile + NADPH + O2 <=> H2O + NADP + 2-hydroxy-2-methylbutyronitrile. GO:0102995 angelicin synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102995 RHEA:27481|EC:1.14.14.148|MetaCyc:RXN-9689 Catalysis of the reaction: columbianetin + NADPH + O2 + H+ <=> angelicin + acetone + NADP + 2 H2O. GO:0102997 progesterone 5beta- reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102997 MetaCyc:RXN-9726 Catalysis of the reaction: H+ + progesterone + NADPH <=> 5beta-pregnane-3,20-dione + NADP. GO:0102996 beta,beta digalactosyldiacylglycerol galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102996 EC:2.4.1.184|MetaCyc:RXN-9721 Catalysis of the reaction: a 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + a beta,beta digalactosyldiacylglycerol <=> a trigalactosyldiacylglycerol + a 1,2-diacyl-sn-glycerol. GO:0102999 UDP-glucose:2-hydroxylamino-4,6-dinitrotoluene-O-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102999 MetaCyc:RXN-9743 Catalysis of the reaction: UDP-alpha-D-glucose + 2-hydroxylamino-4,6-dinitrotoluene <=> 2-hydroxylamino-4,6-dinitrotoluene-O-glucoside + UDP + H+. GO:0102998 4-sulfomuconolactone hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102998 RHEA:33711|EC:3.1.1.92|MetaCyc:RXN-9733 Catalysis of the reaction: (5-oxo-2-sulfonato-2,5-dihydrofuran-2-yl)acetate + H2O <=> maleylacetate + sulfite + 2 H+. GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038096 Fc gamma receptor-dependent phagocytosis|Fcgamma receptor-mediated phagocytosis|Fc-gamma receptor signalling pathway involved in phagocytosis|IgG-mediated phagocytosis An Fc-gamma receptor signaling pathway that contributes to the endocytic engulfment of external particulate material by phagocytes. GO:0038095 Fc-epsilon receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038095 Fc-epsilon receptor signalling pathway A series of molecular signals initiated by the binding of the Fc portion of immunoglobulin E (IgE) to an Fc-epsilon receptor on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region. GO:0038098 sequestering of BMP from receptor via BMP binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038098 extracellular sequestering of BMP|extracellular sequestering of bone morphogenetic protein Binding to a bone morphogenetic protein (BMP) in the extracellular region, and inhibiting BMP signaling by preventing BMP from binding to its cell surface receptor. GO:0038097 positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038097 positive regulation of mast cell activation by Fc-epsilon receptor signalling pathway|Fc epsilon RI-dependent mast cell activation|Fc epsilon RI-mediated mast cell activation An Fc-epsilon receptor signaling pathway that results in the change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors. GO:0038099 nodal receptor complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038099 nodal receptor complex formation|ActRIIB.ALK4.EGF-CFC complex formation The aggregation, arrangement and bonding together of a set of components to form a complex containing a type II activin receptor, a type I activin receptor, and a coreceptor of the EGF-CFC family (e.g. Cripto or Cryptic, in mammals). CHEBI:7621 norajmaline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_7621 GO:0038090 positive regulation of cell migration by VEGF-activated platelet derived growth factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038090 positive regulation of cell migration by VEGF/PDGFR signaling pathway|VEGF/PDGFR-induced cell migration|positive regulation of cell migration by VEGF-activated platelet derived growth factor receptor signalling pathway A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a platelet-derived growth factor receptor (PDGFR) on the surface of a cell, which activates or increases the frequency, rate or extent of the orderly movement of a cell from one site to another. GO:0038092 nodal signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038092 nodal signalling pathway|nodal signaling A series of molecular signals initiated by the binding of a nodal protein to an activin receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0038091 positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038091 VEGF-A-induced cell proliferation|positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signalling pathway|positive regulation of cell proliferation by VEGF/PDGFR signaling pathway A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a platelet-derived growth factor receptor (PDGFR) on the surface of a cell, which activates or increases the frequency, rate or extent of cell proliferation. GO:0038094 Fc-gamma receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038094 Fc-gamma receptor signalling pathway A series of molecular signals initiated by the binding of the Fc portion of immunoglobulin G (IgG) to an Fc-gamma receptor on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region. GO:0038093 Fc receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038093 Fc receptor signalling pathway A series of molecular signals initiated by the binding of the Fc portion of an immunoglobulin to an Fc receptor on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region. CHEBI:147297 omega-hydroxy-ultra-long-chain fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_147297 GO:0038085 vascular endothelial growth factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038085 VEGF binding Interacting selectively and non-covalently with a vascular endothelial growth factor. GO:0038084 vascular endothelial growth factor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038084 vascular endothelial growth factor signalling pathway|VEGF-activated signaling pathway|VEGF signaling A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0038087 VEGF-activated platelet-derived growth factor receptor-alpha signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038087 VEGF-A/PDGFRalpha signaling|VEGF-activated PDGFRalpha signalling pathway|VEGF/PDGFRalpha signaling pathway|vascular endothelial growth factor-activated platelet-derived growth factor receptor-alpha signaling pathway|VEGF-activated platelet-derived growth factor receptor-alpha signalling pathway A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to an alpha-type platelet-derived growth factor receptor (PDGFR) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0038086 VEGF-activated platelet-derived growth factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038086 vascular endothelial growth factor-activated platelet-derived growth factor receptor signaling pathway|VEGF-activated platelet-derived growth factor receptor signalling pathway|VEGF-activated PDGFR signalling pathway|VEGF/PDGFR signaling pathway|VEGF-A/PDGFR signaling A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a platelet-derived growth factor receptor (PDGFR) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0038089 positive regulation of cell migration by vascular endothelial growth factor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038089 positive regulation of cell migration by vascular endothelial growth factor signalling pathway|VEGF-A-induced cell migration|positive regulation of cell migration by VEGF signaling pathway|VEGF-induced cell migration A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a receptor on the surface of a cell, which activates or increases the frequency, rate or extent of the orderly movement of a cell from one site to another. GO:0038088 VEGF-activated platelet-derived growth factor receptor-beta signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038088 VEGF-activated platelet-derived growth factor receptor-beta signalling pathway|VEGF-A/PDGFRbeta signaling|vascular endothelial growth factor-activated platelet-derived growth factor receptor-beta signaling pathway|VEGF-activated PDGFRbeta signalling pathway|VEGF/PDGFRbeta signaling pathway A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a beta-type platelet-derived growth factor receptor (PDGFR) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0038081 obsolete MAP kinase kinase kinase activity involved in osmosensory signaling pathway biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038081 MAP kinase kinase kinase activity involved in osmosensory signalling pathway|MAPKKK activity involved in osmosensory signaling pathway|MAP3K activity involved in osmosensory signaling pathway OBSOLETE. Catalysis of the phosphorylation and activation of a MAP kinase kinase (MAPKK), as part of a MAPK signaling cascade that passes on a signal within an osmosensory signaling pathway. GO:0038080 obsolete MAP kinase kinase activity involved in osmosensory signaling pathway biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038080 MAP2K activity involved in osmosensory signaling pathway|MAPKK activity involved in osmosensory signaling pathway|MAP kinase kinase activity involved in osmosensory signalling pathway OBSOLETE. Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate, as part of a MAPK signaling cascade that passes on a signal within an osmosensory signaling pathway. GO:0038083 peptidyl-tyrosine autophosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038083 tyrosine autophosphorylation|receptor tyrosine kinase autophosphorylation|RTK autophosphorylation The phosphorylation by a protein of one or more of its own tyrosine amino acid residues, or a tyrosine residue on an identical protein. GO:0038082 obsolete MAP kinase phosphatase activity involved in regulation of osmosensory signaling pathway biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038082 MAPK phosphatase activity involved in regulation of osmosensory signaling pathway|MAP kinase phosphatase activity involved in regulation of osmosensory signalling pathway|Hog1 phosphatase activity OBSOLETE. Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate, where the MAP kinase (MAPK) is part of a MAPK signaling cascade that passes on a signal within an osmosensory signaling pathway. CHEBI:147288 omega-hydroxy-ultra-long-chain fatty acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_147288 GO:0038074 obsolete MAP kinase phosphatase activity involved in regulation of conjugation with cellular fusion biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038074 MAPK phosphatase activity involved in regulation of conjugation with cellular fusion OBSOLETE. Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate, where the MAP kinase (MAPK) is part of a MAPK signaling cascade that contributes to conjugation with cellular fusion. GO:0038073 obsolete MAP kinase kinase kinase activity involved in conjugation with cellular fusion biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038073 MAPKKK activity involved in conjugation with cellular fusion|MAP3K activity involved in conjugation with cellular fusion OBSOLETE. Catalysis of the phosphorylation and activation of a MAP kinase kinase (MAPKK), as part of a MAPK signaling cascade that contributes to cell wall biogenesis. GO:0038076 obsolete MAP kinase kinase activity involved in innate immune response biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038076 MAPKK activity involved in innate immune response|MAP2K activity involved in innate immune response OBSOLETE. Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate, as part of a MAPK signaling cascade that contributes to an innate immune response. GO:0038075 obsolete MAP kinase activity involved in innate immune response biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038075 MAPK activity involved in innate immune response OBSOLETE. Catalysis of the reaction: protein + ATP = protein phosphate + ADP by a mitogen-activated protein kinase, as part of a MAPK signaling cascade that contributes to an innate immune response. GO:0038078 MAP kinase phosphatase activity involved in regulation of innate immune response biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038078 MAPK phosphatase activity involved in regulation of innate immune response Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate, where the MAP kinase (MAPK) is part of a MAPK signaling cascade that contributes to an innate immune response. GO:0038077 obsolete MAP kinase kinase kinase activity involved in innate immune response biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038077 MAPKKK activity involved in innate immune response|MAP3K activity involved in innate immune response OBSOLETE. Catalysis of the phosphorylation and activation of a MAP kinase kinase (MAPKK), as part of a MAPK signaling cascade that contributes to an innate immune response. GO:0038079 obsolete MAP kinase activity involved in osmosensory signaling pathway biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038079 MAPK activity involved in osmosensory signaling pathway|MAP kinase activity involved in osmosensory signalling pathway OBSOLETE. Catalysis of the reaction: protein + ATP = protein phosphate + ADP by a mitogen-activated protein kinase, as part of a MAPK signaling cascade that passes on a signal within an osmosensory signaling pathway. GO:0038070 obsolete MAP kinase kinase kinase activity involved in cell wall organization or biogenesis biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038070 MAP3K activity involved in cell wall integrity|MAP kinase kinase kinase activity involved in cell wall biogenesis|MAPKKK activity involved in cell wall integrity OBSOLETE. Catalysis of the phosphorylation and activation of a MAP kinase kinase (MAPKK), as part of a MAPK signaling cascade that contributes to cell wall organization or biogenesis. GO:0038072 obsolete MAP kinase kinase activity involved in conjugation with cellular fusion biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038072 MAPKK activity involved in conjugation with cellular fusion|MAP2K activity involved in conjugation with cellular fusion OBSOLETE. Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate, as part of a MAPK signaling cascade that contributes to conjugation with cellular fusion. GO:0038071 obsolete MAP kinase activity involved in conjugation with cellular fusion biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038071 MAPK activity involved in conjugation with cellular fusion OBSOLETE. Catalysis of the reaction: protein + ATP = protein phosphate + ADP by a mitogen-activated protein kinase, as part of a MAPK signaling cascade that contributes to conjugation with cellular fusion. UBERON:0006098 basal nuclear complex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006098 ganglia basales|corpus striatum (Savel'ev)|basal nuclei|basal ganglia (anatomic)|basal nuclei of the forebrain|basal ganglia The deep nuclei of telencephalic origin found in the basal region of the forebrain GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038063 DDR signaling pathway|discoidin domain receptor signaling pathway|collagen-activated RTK signaling pathway|collagen-activated tyrosine kinase receptor signalling pathway A series of molecular signals initiated by the binding of collagen to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity. The pathway ends with regulation of a downstream cellular process, e.g. transcription. GO:0038062 protein tyrosine kinase collagen receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038062 collagen RTK activity|discoidin domain receptor Combining with collagen and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate. GO:0038065 collagen-activated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038065 collagen-activated signalling pathway A series of molecular signals initiated by collagen binding to a cell surface receptor, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0038064 collagen receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038064 transmembrane collagen receptor activity Combining with a collagen and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0038067 obsolete MAP kinase activity involved in cell wall organization or biogenesis biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038067 MAP kinase activity involved in cell wall integrity|MAP kinase activity involved in cell wall biogenesis|MAPK activity involved in cell wall biogenesis OBSOLETE. Catalysis of the reaction: protein + ATP = protein phosphate + ADP by a mitogen-activated protein kinase, as part of a MAPK signaling cascade that contributes to cell wall organization or biogenesis. GO:0038066 p38MAPK cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038066 p38 MAPK cascade|p38 cascade An intracellular protein kinase cascade containing at least a p38 MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell. GO:0038069 obsolete MAP kinase phosphatase activity involved in regulation of cell wall biogenesis biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038069 Mpk1 phosphatase activity|Slt2 phosphatase activity OBSOLETE. Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate, where the MAP kinase (MAPK) is part of a MAPK signaling cascade that contributes to cell wall biogenesis. GO:0038068 obsolete MAP kinase kinase activity involved in cell wall organization or biogenesis biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038068 MAP kinase kinase activity involved in cell wall biogenesis|MAP2K activity involved in cell wall integrity|MAPKK activity involved in cell wall integrity OBSOLETE. Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate, as part of a MAPK signaling cascade that contributes to cell wall organization or biogenesis. GO:0038061 NIK/NF-kappaB signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038061 noncanonical NF-kappaB signaling|p52-dependent NF-kappaB signaling|noncanonical nuclear factor kappaB (NF-kappaB) pathway|NIK/NF-kappaB signal transduction|non-canonical NF-KB signaling|NIK/NF-kappaB cascade The process in which a signal is passed on to downstream components within the cell through the NIK-dependent processing and activation of NF-KappaB. Begins with activation of the NF-KappaB-inducing kinase (NIK), which in turn phosphorylates and activates IkappaB kinase alpha (IKKalpha). IKKalpha phosphorylates the NF-Kappa B2 protein (p100) leading to p100 processing and release of an active NF-KappaB (p52). GO:0038060 nitric oxide-cGMP-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038060 NO-cGMP signaling pathway|canonical nitric oxide signaling|nitric oxide-cGMP-mediated signalling pathway|classical nitric oxide signaling Any intracellular signal transduction in which the signal is passed on within the cell by nitric oxide (NO) activating soluble guanylyl cyclase (sGC). Includes synthesis of nitric oxide, guanylyl cyclase activity, and downstream effectors that further transmit the signal within the cell following activation by cGMP. GO:0102951 indole-3-acetyl-phenylalanine synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102951 MetaCyc:RXN-9084 Catalysis of the reaction: indole-3-acetate + L-phenylalanine + ATP = H+ + indole-3-acetyl-phenylalanine + AMP + diphosphoric acid. GO:0102950 indole-3-acetyl-valine synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102950 MetaCyc:RXN-9083 Catalysis of the reaction: indole-3-acetate + L-valine + ATP = H+ + indole-3-acetyl-valine + AMP + diphosphoric acid. GO:0102953 hypoglycin A gamma-glutamyl transpeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102953 MetaCyc:RXN-9157|EC:2.3.2.2 Catalysis of the reaction: glutathionate + hypoglycin A = L-cysteinylglycine + hypoglycin B. GO:0102952 UDP-glucose:coniferaldehyde 4-beta-D-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102952 RHEA:57708|MetaCyc:RXN-91 Catalysis of the reaction: UDP-alpha-D-glucose + coniferyl aldehyde = H+ + coniferaldehyde glucoside + UDP. GO:0102955 S-adenosylmethionine:2-demethylmenaquinol-7 methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102955 RHEA:33255|MetaCyc:RXN-9191|EC:2.1.1.163 Catalysis of the reaction: 2-demethylmenaquinol-7 + S-adenosyl-L-methionine = menaquinol-7 + S-adenosyl-L-homocysteine + H+. GO:0102954 dalcochinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102954 MetaCyc:RXN-9162 Catalysis of the reaction: dalcochinin-8'-O-beta-glucoside + H2O <=> dalcochinin + D-glucopyranose. GO:0038059 IKKalpha-IKKalpha complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0038059 IkappaB kinase alpha homodimer|IKKalpha homodimeric complex|IKKalpha homodimer|IKKalpha-IKKalpha protein complex|IkappaB kinase-alpha homodimer A homodimeric protein complex containing two IkappaB kinase (IKK) alpha subunits. GO:0102956 UDP-glucose:sinapaldehyde 4-beta-D-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102956 MetaCyc:RXN-92|RHEA:57712 Catalysis of the reaction: UDP-alpha-D-glucose + sinapoyl aldehyde = H+ + sinapaldehyde glucoside + UDP. GO:0038052 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0038052 GO:0038051 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0038051 GO:0038054 G protein-coupled estrogen receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038054 G-protein coupled estrogen receptor activity Combining with estrogen and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. GO:0038053 obsolete transcription factor activity, estrogen-activated RNA polymerase II transcription factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038053 estrogen-activated RNA polymerase II transcription factor binding transcription factor activity|estrogen nuclear receptor activity OBSOLETE. Combining with estrogen and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. For example, estrogen-bound receptors can bind to transcription factor complexes to regulate transcription of genes whose promoters do not contain estrogen response elements. GO:0038056 negative regulation of BMP signaling pathway by negative regulation of BMP secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038056 negative regulation of BMP signalling pathway by negative regulation of BMP secretion|negative regulation of BMP signaling pathway by negative regulation of bone morphogenetic protein secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway by stopping, preventing or reducing the frequency, rate or extent of secretion of a member of the BMP family of proteins from the signaling cell. GO:0038055 BMP secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038055 bone morphogenetic protein secretion|BMP protein secretion The controlled release of a member of the BMP family of proteins from a cell. GO:0038058 TNFSF11 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038058 tumor necrosis factor ligand superfamily member 11 receptor activity|RANKL receptor activity Combining with a tumor necrosis factor ligand superfamily member 11 (TNFSF11) and transmitting the signal across the cell membrane to initiate a change in cell activity or function. GO:0038057 TNFSF11 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038057 osteoclast differentiation factor binding|receptor activator of nuclear factor kappa-B ligand binding|tumor necrosis factor (ligand) superfamily member 11 binding|tumor necrosis factor superfamily member 11 binding|tumor necrosis factor ligand superfamily member 11 binding|OPGL binding|RANKL binding|TNF-related activation-induced cytokine binding|osteoprotegerin ligand binding|ODF binding|CD254 binding|TRANCE binding Interacting selectively and non-covalently with tumor necrosis factor ligand superfamily member 11 (TNFSF11), a member of the tumor necrosis factor (TNF) cytokine family. GO:0038050 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0038050 GO:0102960 momilactone-A synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102960 EC:1.1.1.295|RHEA:25367|MetaCyc:RXN-9290 Catalysis of the reaction: 3beta-hydroxy-9beta-pimara-7,15-diene-19,6beta-olide + NAD(P) = momilactone A + H+ + NAD(P)H. GO:0102962 4,4'-diapo-zeta-carotene desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102962 MetaCyc:RXN-9305|RHEA:31403 Catalysis of the reaction: all-trans-4,4'-diapo-zeta-carotene + FAD + H+ = 4,4'-diaponeurosporene + FADH2. GO:0102961 4,4'-diapophytofluene desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102961 MetaCyc:RXN-9304|RHEA:31399 Catalysis of the reaction: all-trans-4,4'-diapophytofluene + FAD + H+ = all-trans-4,4'-diapo-zeta-carotene + FADH2. GO:0102964 S-adenosyl-L-methionine:(S)-corytuberine-N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102964 MetaCyc:RXN-9315|RHEA:51524 Catalysis of the reaction: (S)-corytuberine + S-adenosyl-L-methionine <=> H+ + magnoflorine + S-adenosyl-L-homocysteine. GO:0102963 (S)-corytuberine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102963 MetaCyc:RXN-9314|EC:1.14.19.51|RHEA:51540 Catalysis of the reaction: H+ + (S)-reticulinium(1+) + NADPH + O2 <=> (S)-corytuberine + NADP + 2 H2O. GO:0102966 arachidoyl-CoA:1-dodecanol O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102966 MetaCyc:RXN-9356|EC:2.3.1.75 Catalysis of the reaction: icosanoyl-CoA + dodecan-1-ol = arachidoyl dodecanoate + coenzyme A. GO:0102965 alcohol-forming fatty acyl-CoA reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102965 RHEA:52716|MetaCyc:RXN-9344|EC:1.2.1.84 Catalysis of the reaction: 2 NADPH + 2 H+ + a long-chain acyl-CoA = coenzyme A + 2 NADP + a long-chain alcohol. GO:0102968 10-hydroxygeranial oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102968 MetaCyc:RXN-9369|RHEA:32611 Catalysis of the reaction: (6E)-8-hydroxygeranial + NADP <=> (6E)-8-oxogeranial + NADPH + H+. GO:0038049 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0038049 GO:0038048 dynorphin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038048 kappa-opioid receptor activity Combining with a dynorphin peptide, and transmitting the signal across the membrane by activating an associated G-protein. Dynorphin is any opioid peptide that is generated by cleavage of the precursor protein prodynorphin. GO:0102967 10-hydroxygeraniol oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102967 RHEA:32607|MetaCyc:RXN-9367 Catalysis of the reaction: (6E)-8-hydroxygeraniol + NADP <=> (6E)-8-hydroxygeranial + NADPH + H+. GO:0102969 10-oxogeraniol oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102969 RHEA:32615|MetaCyc:RXN-9370 Catalysis of the reaction: (6E)-8-oxogeraniol + NADP <=> (6E)-8-oxogeranial + NADPH + H+. GO:0038041 cross-receptor inhibition within G protein-coupled receptor heterodimer biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038041 cross-receptor inhibition within G-protein coupled receptor heterodimer Inhibition of one protomer of a G protein-coupled receptor (GPCR) heterodimer by the associated subunit. For example, agonist activation of one cytokine receptor can prevent activation of its associated cytokine receptor subunit. GO:0038040 obsolete cross-receptor activation within G-protein coupled receptor heterodimer biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038040 OBSOLETE. Activation of one protomer of a consequence of a G protein-coupled (GPCR) heterodimer by the associated subunit. For example, agonist occupancy in one protomer of a GPCR dimer may activate the associated promoter. GO:0038043 interleukin-5-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038043 IL-5-mediated signaling pathway|interleukin-5-mediated signalling pathway A series of molecular signals initiated by the binding of interleukin-5 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. CHEBI:7671 O-acetylhomoserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_7671 GO:0038042 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0038042 GO:0038045 large latent transforming growth factor-beta complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0038045 LLC|large latent complex A protein complex containing latency-associated proteins (LAPs), mature disulphide-linked dimeric TGF-beta, and latent TGF-beta binding proteins (LTBPs). TGF-beta is mostly secreted as part of the large latent complex, and must be subsequently released from the LLC in order to bind to cell surface receptors. CHEBI:7676 O-butanoylcarnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_7676 GO:0038044 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0038044 GO:0038047 morphine receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038047 mu-opioid receptor activity Combining with morphine (17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol), and transmitting the signal across the membrane by activating an associated G-protein. GO:0038046 enkephalin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038046 delta-opioid receptor activity Combining with an enkephalin, and transmitting the signal across the membrane by activating an associated G-protein. A enkephalin is a pentapeptide (Tyr-Gly-Gly-Phe-Met or Tyr-Gly-Gly-Phe-Leu) involved in regulating nociception in the body. GO:0014070 response to organic cyclic compound biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014070 response to organic cyclic substance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus. GO:0102971 phosphinothricin N-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102971 MetaCyc:RXN-9382|RHEA:12597|EC:2.3.1.183 Catalysis of the reaction: acetyl-CoA + phosphinothricin <=> H+ + coenzyme A(4-) + N-acetylphosphinatothricinate. GO:0102970 7-deoxyloganetic acid glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102970 MetaCyc:RXN-9372|RHEA:39895|EC:2.4.1.323 Catalysis of the reaction: UDP-alpha-D-glucose + 7-deoxyloganetate <=> H+ + 7-deoxyloganate + UDP. GO:0102973 norsolorinate anthrone synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102973 MetaCyc:RXN-9479|RHEA:35179|EC:2.3.1.221 norsolorinic acid synthase Catalysis of the reaction: 7 malonyl-CoA + 5 H+ + a hexanoyl-[acyl-carrier-protein] = norsolorinate anthrone + 7 coenzyme A + 7 carbon dioxide + 2 H2O + a holo-[acyl-carrier protein]. GO:0102972 gibberellin A12,2-oxoglutarate:oxygen oxidoreductase activity (gibberellin A110-forming) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102972 MetaCyc:RXN-947 Catalysis of the reaction: gibberellin A12 + 2-oxoglutarate + O2 = gibberellin A110 + succinate + carbon dioxide. GO:0102975 versiconal hemiacetal acetate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102975 MetaCyc:RXN-9490|RHEA:35695|EC:1.1.1.353 Catalysis of the reaction: versiconol acetate + NADP <=> versiconal hemiacetal acetate + NADPH. GO:0102974 hydroxyversicolorone reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102974 MetaCyc:RXN-9489|RHEA:35691|EC:1.1.1.353 Catalysis of the reaction: versicolorone + NADP = hydroxyversicolorone + NADPH. GO:0102977 nitrilotriacetate monooxygenase activity (FMN-dependent) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102977 RHEA:31359|MetaCyc:RXN-9508|EC:1.14.14.10 Catalysis of the reaction: nitrilotriacetate + O2 + FMNH2 = ammoniodiacetate + 2-oxo monocarboxylic acid anion + H2O + FMN. GO:0102976 versiconal reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102976 RHEA:35699|MetaCyc:RXN-9491|EC:1.1.1.353 Catalysis of the reaction: versiconol + NADP <=> versiconal hemiacetal + NADPH + H+. GO:0038038 G protein-coupled receptor homodimeric complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0038038 G-protein coupled receptor homodimer|GPCR homodimer|G-protein coupled receptor homodimeric complex A protein complex that contains two G protein-coupled receptors (GPCRs) of the same subtype. Formation of a GPCR homodimer may be important for the transport of newly formed receptors to the cell surface, and the function of the receptor. GO:0102979 homofuraneol oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102979 RHEA:53944|MetaCyc:RXN-9564 Catalysis of the reaction: homofuraneol + NADP <=> (2E)-2-ethylidene-4-hydroxy-5-methyl-3(2H)-furanone + NADPH + H+. GO:0038037 G protein-coupled receptor dimeric complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0038037 G-protein coupled receptor dimer|GPCR dimer|G-protein coupled receptor dimeric complex A protein complex that contains two G protein-coupled receptors. GO:0102978 furaneol oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102978 MetaCyc:RXN-9563|EC:1.3.1.105|RHEA:39111 Catalysis of the reaction: 4-hydroxy-2,5-dimethylfuran-3-one + NADP <=> 4-hydroxy-5-methyl-2-methylenefuran-3-one + NADPH + H+. GO:0014069 postsynaptic density biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0014069 Wikipedia:Postsynaptic_density|NIF_Subcellular:sao1196688972 neuronal postsynaptic density|post-synaptic density|postsynaptic density of dendrite|post synaptic density An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components. GO:0038039 G protein-coupled receptor heterodimeric complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0038039 GPCR heterodimer|G-protein coupled receptor heterodimer|G-protein coupled receptor heterodimeric complex A protein complex that contains two G protein-coupled receptors (GPCRs) of different subtypes. Formation of a GPCR heterodimer may alter the functional property of the GPCR. GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014068 up regulation of phosphatidylinositol 3-kinase cascade|stimulation of phosphatidylinositol 3-kinase cascade|positive regulation of phosphatidylinositol 3-kinase cascade|up-regulation of phosphatidylinositol 3-kinase cascade|positive regulation of PI3K cascade|positive regulation of PI 3-kinase cascade|upregulation of phosphatidylinositol 3-kinase cascade|activation of phosphoinositide 3-kinase cascade|positive regulation of phosphoinositide 3-kinase cascade Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade. GO:0014063 negative regulation of serotonin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014063 positive regulation of serotonin release|down regulation of serotonin secretion|downregulation of serotonin secretion|down-regulation of serotonin secretion|inhibition of serotonin secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of serotonin. GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038030 non-canonical Wnt receptor signaling pathway via MAPKKK cascade|non-canonical Wnt receptor signaling pathway via MAPK signaling|non-canonical Wnt-activated signaling pathway via MAPK cascade|non-canonical Wnt receptor signalling pathway via MAPKKK cascade|non-canonical Wnt receptor signaling pathway via MAPK cascade The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, where the signal is passed on via the MAPKKK cascade. GO:0014062 regulation of serotonin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014062 regulation of serotonin release Any process that modulates the frequency, rate or extent of the regulated release of serotonin. GO:0014061 regulation of norepinephrine secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014061 regulation of noradrenaline secretion Any process that modulates the frequency, rate or extent of the regulated release of norepinephrine. GO:0038032 termination of G protein-coupled receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038032 termination of G-protein coupled receptor signalling pathway|termination of GPCR signaling pathway|termination of G-protein coupled receptor signaling pathway The signaling process in which G protein-coupled receptor signaling is brought to an end. For example, through the action of GTPase-activating proteins (GAPs) that act to accelerate hydrolysis of GTP to GDP on G-alpha proteins, thereby terminating the transduced signal. GO:0014060 regulation of epinephrine secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014060 regulation of adrenaline secretion Any process that modulates the frequency, rate or extent of the regulated release of epinephrine. GO:0038031 non-canonical Wnt signaling pathway via JNK cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038031 non-canonical Wnt-activated signaling pathway via JNK cascade|non-canonical Wnt receptor signaling pathway via JNK cascade|non-canonical Wnt receptor signalling pathway via JNK cascade The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, where the signal is passed on via the JNK cascade. GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014067 negative regulation of phosphoinositide 3-kinase cascade|downregulation of phosphatidylinositol 3-kinase cascade|down-regulation of phosphatidylinositol 3-kinase cascade|negative regulation of phosphatidylinositol 3-kinase cascade|inhibition of phosphatidylinositol 3-kinase cascade|negative regulation of PI3K cascade|negative regulation of PI 3-kinase cascade|down regulation of phosphatidylinositol 3-kinase cascade Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade. GO:0038034 signal transduction in absence of ligand biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038034 basal signaling|dependence receptor signaling pathway|signal transduction in absence of agonist|non-classical signal transduction|addiction receptor signaling pathway|negative signal transduction A series of molecular signals initiated by the absence of a ligand or the withdrawal of a ligand from a receptor. GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signalling pathway|VEGF-mediated chemotactic endothelial cell migration|positive regulation of endothelial cell chemotaxis by VEGF/VEGFR signaling pathway|vascular endothelial growth factor receptor signaling pathway involved in endothelial cell chemotaxis|VEGF-VEGFR-induced endothelial cell chemotaxis A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a VEGFR on the surface of a cell, which activates or increases the frequency, rate or extent of endothelial cell chemotaxis. GO:0014066 regulation of phosphatidylinositol 3-kinase signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014066 regulation of phosphatidylinositol 3-kinase cascade|regulation of phosphoinositide 3-kinase cascade|regulation of PI 3-kinase cascade|regulation of PI3K cascade Any process that modulates the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade. GO:0014065 phosphatidylinositol 3-kinase signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014065 phosphoinositide 3-kinase cascade|PI3K cascade|phosphatidylinositol 3-kinase signal transduction|PI3K signaling|PI3K signal transduction|phosphatidylinositol 3-kinase cascade|PI 3-kinase cascade A series of reactions within the signal-receiving cell, mediated by the intracellular phosphatidylinositol 3-kinase (PI3K). Many cell surface receptor linked signaling pathways signal through PI3K to regulate numerous cellular functions. GO:0038036 sphingosine-1-phosphate receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038036 S1P receptor activity Combining with the sphingolipid sphingosine-1-phosphate (S1P), and transmitting the signal across the membrane by activating an associated G-protein. GO:0014064 positive regulation of serotonin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014064 positive regulation of serotonin release|upregulation of serotonin secretion|up regulation of serotonin secretion|activation of serotonin secretion|stimulation of serotonin secretion|up-regulation of serotonin secretion Any process that activates or increases the frequency, rate or extent of the regulated release of serotonin. GO:0038035 G protein-coupled receptor signaling in absence of ligand biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038035 basal G-protein coupled receptor signaling|G-protein coupled receptor signaling in absence of ligand|G-protein coupled receptor signaling in absence of agonist|G-protein coupled receptor signalling in absence of ligand A series of molecular signals beginning with a consequence of a G protein-coupled receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex, where the G protein-coupled receptor is not bound to an agonist. GO:0102980 2-butyl-4-hydroxy-5-methyl-3(2H)-furanoneoxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102980 MetaCyc:RXN-9565 Catalysis of the reaction: 2-butyl-4-hydroxy-5-methyl-3(2H)-furanone + NADP <=> (2E)-2-butylidene-4-hydroxy-5-methyl-3(2H)-furanone + NADPH + H+. GO:0102982 UDP-3-dehydro-alpha-D-glucose dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102982 MetaCyc:RXN-9578|RHEA:35755 Catalysis of the reaction: UDP-alpha-D-glucose + NAD <=> H+ + UDP-3-keto-alpha-D-glucose + NADH. GO:0102981 4-hydroxy-5-methyl-2-propyl-3(2H)-furanone oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102981 MetaCyc:RXN-9567 Catalysis of the reaction: 4-hydroxy-5-methyl-2-propyl-3(2H)-furanone + NADP <=> (2E)-4-hydroxy-5-methyl-2-propylidene-3(2H)-furanone + NADPH + H+. GO:0102984 sulfoacetaldehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102984 RHEA:25637|EC:1.2.1.73|MetaCyc:RXN-9592 Catalysis of the reaction: sulfonatoacetaldehyde + H2O + NAD <=> sulfonatoacetate + NADH + 2 H+. GO:0102983 xylogalacturonan beta-1,3-xylosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102983 MetaCyc:RXN-9589|EC:2.4.2.41 Catalysis of the reaction: UDP-alpha-D-xylose + a homogalacturonan <=> UDP + 4 H+ + a xylogalacturonan. GO:0102986 trehalose synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102986 EC:2.4.1.245|MetaCyc:RXN-9603|RHEA:47416 Catalysis of the reaction: an NDP-alpha-D-glucose + D-glucopyranose <=> alpha,alpha-trehalose + H+ + a nucleoside diphosphate. GO:0102985 Delta12-fatty-acid desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102985 EC:1.14.19.6|MetaCyc:RXN-9601|RHEA:25856 Catalysis of the reaction: oleoyl-CoA + O2 + a reduced electron acceptor <=> linoleoyl-CoA + 2 H2O + an oxidized electron acceptor. GO:0102988 9,12-cis-hexadecadienoic acid delta 15 desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102988 MetaCyc:RXN-9617|RHEA:46232 Catalysis of the reaction: (9Z,12Z)-hexadecadienoyl-CoA + O2 + a reduced electron acceptor <=> 9,12,15-cis-hexadecatrienoyl-CoA + 2 H2O + an oxidized electron acceptor. GO:0102987 palmitoleic acid delta 12 desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102987 RHEA:45096|MetaCyc:RXN-9616 Catalysis of the reaction: palmitoleoyl-CoA + O2 + a reduced electron acceptor <=> (9Z,12Z)-hexadecadienoyl-CoA + 2 H2O + an oxidized electron acceptor. GO:0038027 apolipoprotein A-I-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038027 apolipoprotein A-I-mediated signalling pathway A series of molecular signals initiated by the binding of apolipoprotein A-I to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0038026 reelin-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038026 reelin-mediated signalling pathway|reeler-mediated signaling pathway|reelin-mediated signal transduction pathway A series of molecular signals initiated by the binding of reelin (a secreted glycoprotein) to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0102989 5-pentadecatrienylresorcinol synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102989 MetaCyc:RXN-9618 Catalysis of the reaction: 3 H+ + 9,12,15-cis-hexadecatrienoyl-CoA + 3 malonyl-CoA(5-) <=> 5-(pentadeca-8,11,14-trien-1-yl)resorcinol + 4 coenzyme A + 4 carbon dioxide. GO:0038029 epidermal growth factor receptor signaling pathway via MAPK cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038029 EGFR signaling via MAPKKK cascade|epidermal growth factor receptor signaling pathway via MAPKKK cascade|EGFR/MAPK signaling|EGFR signaling pathway via MAPKKK cascade|epidermal growth factor receptor signalling pathway via MAPKKK cascade The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to one of its physiological ligands, where the signal is passed on via the MAPKKK cascade. GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038028 insulin receptor signaling pathway via PI3K cascade|insulin receptor signalling pathway via phosphatidylinositol 3-kinase cascade|insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade|insulin receptor signaling via PI3K The series of molecular signals generated as a consequence of the insulin receptor binding to its physiological ligand, where the signal is passed on via the phosphatidylinositol 3-kinase cascade. GO:0014074 response to purine-containing compound biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014074 response to purine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purine-containing compound stimulus. GO:0014073 response to tropane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014073 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tropane stimulus. Tropane is a nitrogenous bicyclic organic compound mainly known for a group of alkaloids derived from it (called tropane alkaloids), which include, among others, atropine and cocaine. GO:0014072 response to isoquinoline alkaloid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014072 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isoquinoline alkaloid stimulus. An isoquinoline alkaloid is any member of a group of compounds with the heterocyclic ring structure of benzo(c)pyridine which is a structure characteristic of the group of opium alkaloids. GO:0038021 leptin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038021 Combining with the fat-cell specific hormone leptin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0038020 insulin receptor recycling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038020 The process that results in the return of an insulin receptor to an active state at the plasma membrane. An active state is when the receptor is ready to receive an insulin signal. Internalized insulin receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation. GO:0014071 response to cycloalkane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014071 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloalkane stimulus. A cycloalkane is a cyclic saturated hydrocarbon having the general formula CnH2n. GO:0038023 signaling receptor activity biolink:MolecularActivity go-plus goslim_flybase_ribbon|goslim_chembl|goslim_mouse|goslim_agr|goslim_pir|goslim_plant|goslim_drosophila|goslim_metagenomics http://purl.obolibrary.org/obo/GO_0038023 receptor activity involved in signal transduction|signalling receptor activity|receptor activity Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response. GO:0038022 G protein-coupled olfactory receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038022 odorant receptor activity, G-protein coupled|G-protein coupled olfactory receptor activity|G-protein coupled odorant receptor activity|olfactory receptor activity, G-protein coupled Combining with an odorant and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. GO:0038025 reelin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038025 reeler receptor activity Combining with the secreted glycoprotein reelin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0014076 response to fluoxetine biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0014076 response to selective serotonin reuptake inhibitor|response to SSRI Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor. GO:0038024 cargo receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038024 Reactome:R-HSA-3000122|Reactome:R-HSA-350168 receptor activity|transport receptor activity|endocytic receptor activity|receptor activity involved in receptor-mediated endocytosis Binding specifically to a substance (cargo) to deliver it to a transport vesicle. Cargo receptors span a membrane (either the plasma membrane or a vesicle membrane), binding simultaneously to cargo molecules and coat adaptors, to efficiently recruit soluble proteins to nascent vesicles. GO:0014075 response to amine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014075 response to amine stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups. CHEBI:18634 (L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18634 PO:0025099 embryo plant structure biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025099 胚性植物構造 (Japanese, exact)|embryonic plant structure (exact)|estructura vegetal embriónica (Spanish, exact) A plant structure (PO:0009011) that is part of an plant embryo (PO:0009009). PO:0025097 stamen epidermis biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025097 雄蕊表皮 (Japanese, exact)|epidermis del estambre (Spanish, exact) A portion of phyllome epidermis (PO:0025157) that is part of a stamen (PO:0009029). PO:0025096 carpel epidermis biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025096 心皮 表皮 (Japanese, exact)|A portion of carpel epidermis (PO:0025096) that covers the abaxial surface of a carpel (PO:0009030). " (broad)|epidermis del carpelo (Spanish, exact) A portion of phyllome epidermis (PO:0025157) that is part of a carpel (PO:0009030). PO:0025095 root parenchyma biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025095 根柔組織 (Japanese, exact)|parénquima de la raíz (Spanish, exact) A portion of parenchyma tissue (PO:0005421) that is part of a root (PO:0009005). PO:0025094 sporangium biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025094 moss capsule (exact)|spore case (exact)|esporangio (Spanish, exact)|sporangia (exact, plural)|胞子嚢 (Japanese, exact)|spore capsule (exact) A plant organ (PO:0009008) in which plant spores (PO:0025017) are produced. PO:0025092 dehiscence zone biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025092 裂開帯 (Japanese, exact)|zona de dehiscencia (Spanish, exact) A portion of plant tissue (PO:0009007) that is part of a plant structure and consists of a narrow band of cells that undergoes dehiscence upon maturation of the structure. NCBITaxon:41665 Neopterygii organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_41665 Neopterygi PO:0025082 reproductive shoot system biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025082 生殖シュート 系、苗条系 (Japanese, exact)|sistema de brote reproductivo (Spanish, exact) A shoot system (PO:0009006) in the sporophytic phase that has as part at least one sporangium (PO:0025094). CHEBI:18657 (R)-2-trans-abscisic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18657 PO:0025078 placenta biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025078 placentas (exact, plural)|placenta (Spanish, exact)|portion of placenta tissue (exact)|胎座 (Japanese, exact)|placentae (exact, plural) A portion of plant tissue (PO:0009007) at the interface between two plant structures, one of which is in a gametophyte development stage (PO:0028003) and one of which is in a sporophyte development stage (PO:0028002), and that has as parts transfer cells (PO:0000078). PO:0025074 embryo sac biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025074 胚嚢 (Japanese, exact)|saco embrionario (Spanish, exact) A megagametophyte (PO:0025279) that is located in a plant ovary ovule (PO:0025490). CHEBI:371 (S)-1-pyrroline-5-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_371 UBERON:0006072 cervical region of vertebral column biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006072 cervical vertebrae series|cervical skeleton|cervical vertebral column|axial skeleton cervical region|skeletal system of neck|cervical spinal column|cervical spine That portion of the spine comprising the cervical vertebrae. The neck area of the spine. UBERON:0006071 caudal region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006071 post-anal tail region|tail region|post-anal caudal region|postsacral region Subdivision of an organism along anterior-posterior axis that is the posteriormost region, extending past the anus (or cloaca, if present), consisting of a tail in some fully formed chordates (or a tail bud in embryos). In animals that have a sacral region, this is the region immediately posterior to this. UBERON:0006077 subdivision of vertebral column biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006077 vertebral series|vertebral region|vertebral subdivision|subdivision of vertebral skeleton|vertebral column subdivision|vertebrae series A collection of all skeletal elements in some subdivision of the vertebral column. UBERON:0006076 caudal region of vertebral column biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006076 postsacral region|tail region|caudal vertebrae series|caudal region|caudal skeleton|axial skeleton tail region Subdivision of vertebral column that corresponds to the caudal subdivision of the body, containing the caudal vertebrae. UBERON:0006073 thoracic region of vertebral column biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006073 thoracic vertebrae series|thoracic spine|thoracic vertebral column|axial skeleton thoracic region|columna vertebralis thoracicus That part of the spine comprising the thoracic vertebrae. UBERON:0006061 process of vertebra biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006061 vertebra process|spinous process|vertebral process A process projection from a part of the vertebra such as centrum or arches. Examples: transverse process, diapophyses, parapophyses, and zygapophyses (both the cranial zygapophyses and the caudal zygapophyses). UBERON:0006068 bone of tail biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006068 tail bone|tail vertebra A bone that is part of a post-anal tail. UBERON:0006067 musculature of hindlimb zeugopod biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006067 muscle group of leg|leg musculature|set of muscles of leg Any collection of muscles that is part of a hindlimb zeugopod. UBERON:0006063 cartilaginous neural arch biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006063 neural arch primordium One of the cartilaginous structures surrounding the embryonic spinal cord, formed by the dorsal growth of the dorsolateral arcualia; it is the primordium of the vertebral arch. CHEBI:18608 5-methyltetrahydrofolate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_18608 UBERON:0006058 multi-limb segment region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006058 A collection of two or more connected limb segments. Examples: arm (comprising stylopod and zeugopod regions). UBERON:0006056 posterior surface of head biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006056 GO:0004646 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004646 GO:0004645 1,4-alpha-oligoglucan phosphorylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004645 EC:2.4.1.1|MetaCyc:RXN-1826 starch phosphorylase|granulose phosphorylase|muscle phosphorylase a and b activity|muscle phosphorylase|1,4-alpha-glucan phosphorylase activity|amylophosphorylase activity|potato phosphorylase|1,4-alpha-D-glucan:phosphate alpha-D-glucosyltransferase activity|glucosan phosphorylase|glucan phosphorylase|polyphosphorylase activity|alpha-glucan phosphorylase|myophosphorylase|amylopectin phosphorylase Catalysis of the reaction: 1,4-alpha-D-glucosyl(n) + phosphate = 1,4-alpha-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate. The name should be qualified in each instance by adding the name of the natural substrate, e.g. maltodextrin phosphorylase, starch phosphorylase, glycogen phosphorylase. GO:0004648 O-phospho-L-serine:2-oxoglutarate aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004648 Reactome:R-HSA-977333|RHEA:14329|MetaCyc:PSERTRANSAM-RXN|EC:2.6.1.52 phosphohydroxypyruvate transaminase activity|phosphoserine aminotransferase activity|hydroxypyruvic phosphate--glutamic transaminase activity|phosphohydroxypyruvic--glutamic transaminase activity|phosphoserine transaminase activity|3-phosphoserine aminotransferase activity|3-O-phospho-L-serine:2-oxoglutarate aminotransferase activity|SerC|L-phosphoserine aminotransferase activity|PdxC|3PHP transaminase activity|PSAT activity Catalysis of the reaction: O-phospho-L-serine + 2-oxoglutarate = 3-phosphonooxypyruvate + L-glutamate. GO:0004647 phosphoserine phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004647 MetaCyc:PSERPHOSPHA-RXN|EC:3.1.3.3|Reactome:R-HSA-977324 O-phosphoserine phosphohydrolase activity Catalysis of the reaction: L(or D)-O-phosphoserine + H2O = L(or D)-serine + phosphate. GO:0004642 phosphoribosylformylglycinamidine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004642 Reactome:R-HSA-73812|EC:6.3.5.3|RHEA:17129|KEGG_REACTION:R04463|MetaCyc:FGAMSYN-RXN phosphoribosylformylglycinamidine synthetase activity|2-N-formyl-1-N-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming)|phosphoribosylformylglycineamidine synthetase activity|FGARAT activity|N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming)|FGAM synthase activity|FGAR amidotransferase activity|formylglycinamide ribonucloetide amidotransferase activity|5'-phosphoribosylformylglycinamide:L-glutamine amido-ligase (ADP-forming)|formylglycinamide ribotide amidotransferase activity|FGAM synthetase activity Catalysis of the reaction: N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + ATP + H(2)O = 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate + ADP + 2 H(+) + phosphate. GO:0004641 phosphoribosylformylglycinamidine cyclo-ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004641 KEGG_REACTION:R04208|EC:6.3.3.1|RHEA:23032|Reactome:R-HSA-73810|MetaCyc:AIRS-RXN 5'-aminoimidazole ribonucleotide synthetase activity|2-(formamido)-1-N-(5-phosphoribosyl)acetamidine cyclo-ligase (ADP-forming)|AIRS activity|2-(formamido)-N1-(5-phosphoribosyl)acetamidine cyclo-ligase (ADP-forming)|AIR synthase activity|phosphoribosylaminoimidazole synthetase activity|phosphoribosyl-aminoimidazole synthetase activity|AIR synthetase activity Catalysis of the reaction: 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + ATP = 5-amino-1-(5-phospho-D-ribosyl)imidazole + ADP + 2 H(+) + phosphate. GO:0004644 phosphoribosylglycinamide formyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004644 Reactome:R-HSA-73813|MetaCyc:GART-RXN|RHEA:15053|EC:2.1.2.2 2-amino-N-ribosylacetamide 5'-phosphate transformylase activity|GAR formyltransferase activity|glycinamide ribonucleotide transformylase activity|5'-phosphoribosylglycinamide transformylase activity|GAR TFase activity|GART activity|GAR transformylase activity|10-formyltetrahydrofolate:5'-phosphoribosylglycinamide N-formyltransferase activity|5,10-methenyltetrahydrofolate:2-amino-N-ribosylacetamide ribonucleotide transformylase activity Catalysis of the reaction: 10-formyltetrahydrofolate + N1-(5-phospho-D-ribosyl)glycinamide = tetrahydrofolate + N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide. GO:0004643 phosphoribosylaminoimidazolecarboxamide formyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004643 MetaCyc:AICARTRANSFORM-RXN|RHEA:22192|EC:2.1.2.3|Reactome:R-HSA-73798 AICAR transformylase activity|10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazole-carboxamide N-formyltransferase activity|5-amino-1-ribosyl-4-imidazolecarboxamide 5'-phosphate transformylase activity|5-amino-4-imidazolecarboxamide ribotide transformylase activity|5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase activity|aminoimidazolecarboxamide ribonucleotide transformylase activity|5-amino-4-imidazolecarboxamide ribonucleotide transformylase activity|10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase activity|AICAR formyltransferase activity Catalysis of the reaction: 10-formyltetrahydrofolate + 5'-phosphoribosyl-5-amino-4-imidazolecarboxamide = tetrahydrofolate + 5'-phosphoribosyl-5-formamido-4-imidazolecarboxamide. GO:0004640 phosphoribosylanthranilate isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004640 MetaCyc:PRAISOM-RXN|EC:5.3.1.24|RHEA:21540|KEGG_REACTION:R03509 PRA isomerase activity|N-(5'-phosphoribosyl)anthranilate isomerase activity|IGPS:PRAI (indole-3-glycerol-phosphate synthetase/N-5'-phosphoribosylanthranilate isomerase complex)|N-(5-phospho-beta-D-ribosyl)anthranilate aldose-ketose-isomerase activity|PRAI activity|N-(5-phospho-beta-D-ribosyl)anthranilate ketol-isomerase activity Catalysis of the reaction: N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. CHEBI:137932 5-dehydro-L-gluconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137932 CHEBI:137931 TDP-alpha-D-glucose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137931 CHEBI:137935 S-polyprenyl-L-cysteine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137935 CHEBI:137934 polyprenal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137934 CHEBI:137933 N(4)-methyl-dCMP(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137933 GO:0004649 poly(ADP-ribose) glycohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004649 Reactome:R-HSA-5651828|RHEA:52216|Reactome:R-HSA-8952903|MetaCyc:3.2.1.143-RXN|EC:3.2.1.143 Catalysis of the hydrolysis of poly(ADP-ribose) at glycosidic (1''-2') linkage of ribose-ribose bond to produce free ADP-ribose. GO:0004657 proline dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004657 Reactome:R-HSA-6784224|Reactome:R-HSA-70670|EC:1.5.99.8|Reactome:R-HSA-8955817|MetaCyc:RXN-7181|RHEA:23784 L-proline:(acceptor) oxidoreductase activity|L-proline:acceptor oxidoreductase activity|L-proline dehydrogenase activity Catalysis of the reaction: L-proline + acceptor = (S)-1-pyrroline-5-carboxylate + reduced acceptor. GO:0004656 procollagen-proline 4-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004656 MetaCyc:1.14.11.2-RXN|EC:1.14.11.2|KEGG_REACTION:R03219|RHEA:18945|Reactome:R-HSA-1650808 procollagen-proline,2-oxoglutarate-4-dioxygenase activity|protocollagen hydroxylase activity|protocollagen proline 4-hydroxylase activity|peptidyl proline hydroxylase activity|protocollagen prolyl hydroxylase activity|hydroxylase, collagen proline activity|prolylprotocollagen hydroxylase activity|prolyl-glycyl-peptide, 2-oxoglutarate:oxygen oxidoreductase, 4-hydroxylating activity|prolyl hydroxylase activity|protocollagen proline dioxygenase activity|procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) activity|collagen proline hydroxylase activity|prolyl 4-hydroxylase activity|proline,2-oxoglutarate 4-dioxygenase activity|proline, 2-oxoglutarate dioxygenase activity|protocollagen proline hydroxylase activity|proline protocollagen hydroxylase activity|prolylprotocollagen dioxygenase activity|proline hydroxylase activity Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + CO2. GO:0004659 prenyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004659 Reactome:R-HSA-6806674|MetaCyc:GPPSYN-RXN Catalysis of the transfer of a prenyl group from one compound (donor) to another (acceptor). GO:0004658 propionyl-CoA carboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004658 MetaCyc:PROPIONYL-COA-CARBOXY-RXN|Reactome:R-HSA-71031|RHEA:23720|EC:6.4.1.3 propanoyl-CoA:carbon-dioxide ligase (ADP-forming)|propionyl coenzyme A carboxylase activity|PCCase activity Catalysis of the reaction: ATP + propanoyl-CoA + HCO3- = ADP + phosphate + (S)-methylmalonyl-CoA. PO:0025131 plant anatomical entity biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025131 entidad anatómica vegetal (Spanish, exact)|植物 解剖学（形態）的実体 (Japanese, exact) An anatomical entity that is or was part of a plant. GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004653 MetaCyc:2.4.1.41-RXN|Reactome:R-HSA-9683760|Reactome:R-HSA-913675|Reactome:R-HSA-5096532|EC:2.4.1.41|Reactome:R-HSA-5096537|Reactome:R-HSA-8851619|Reactome:R-HSA-9694438 UDP-N-acetylgalactosamine-glycoprotein N-acetylgalactosaminyltransferase activity|UDP-acetylgalactosamine-glycoprotein acetylgalactosaminyltransferase activity|polypeptide-N-acetylgalactosamine transferase activity|UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase activity|UDP-N-acetylgalactosamine:kappa-casein polypeptide N-acetylgalactosaminyltransferase activity|UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyl-transferase activity|protein-UDP acetylgalactosaminyltransferase activity|UDP-N-acetylgalactosamine-protein N-acetylgalactosaminyltransferase activity|uridine diphosphoacetylgalactosamine-glycoprotein acetylgalactosaminyltransferase activity|UDP-GalNAc:polypeptide N-acetylgalactosaminyl transferase activity|glycoprotein acetylgalactosaminyltransferase activity|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase activity|UDP-N-acetylgalactosamine:protein N-acetylgalactosaminyl transferase activity|UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferase activity|UDP-acetylgalactosamine:peptide-N-galactosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + polypeptide = UDP + N-acetyl-D-galactosaminyl-polypeptide. This reaction is the modification of serine or threonine residues in polypeptide chains by the transfer of a N-acetylgalactose from UDP-N-acetylgalactose to the hydroxyl group of the amino acid; it is the first step in O-glycan biosynthesis. GO:0004652 polynucleotide adenylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004652 Reactome:R-HSA-72185|MetaCyc:POLYNUCLEOTIDE-ADENYLYLTRANSFERASE-RXN|EC:2.7.7.19|RHEA:11332 ATP:polynucleotidylexotransferase activity|RNA adenylating enzyme activity|AMP polynucleotidylexotransferase activity|polyadenylic acid polymerase activity|ATP:polynucleotide adenylyltransferase activity|terminal riboadenylate transferase activity|polyadenylate nucleotidyltransferase activity|poly(A) hydrolase activity|NTP polymerase activity|polyadenylate polymerase activity|adenosine triphosphate:ribonucleic acid adenylyltransferase activity|polyadenylic polymerase activity|poly(A) polymerase activity|polyadenylate synthetase activity|ATP-polynucleotide adenylyltransferase activity|RNA formation factors, PF1|poly(A) synthetase activity|poly-A polymerase activity Catalysis of the template-independent extension of the 3'- end of an RNA or DNA strand by addition of one adenosine molecule at a time. Cannot initiate a chain 'de novo'. The primer, depending on the source of the enzyme, may be an RNA or DNA fragment, or oligo(A) bearing a 3'-OH terminal group. GO:0004655 porphobilinogen synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004655 EC:4.2.1.24|KEGG_REACTION:R00036|MetaCyc:PORPHOBILSYNTH-RXN|Reactome:R-HSA-189439|RHEA:24064 delta-aminolevulinic dehydratase activity|delta-aminolevulinic acid dehydratase activity|aminolevulinate dehydratase activity|aminolevulinic dehydratase activity|5-aminolevulinate hydro-lyase (adding 5-aminolevulinate and cyclizing)|5-aminolevulinate hydro-lyase (adding 5-aminolevulinate and cyclizing; porphobilinogen-forming)|5-levulinic acid dehydratase activity|delta-aminolevulinate dehydratase activity|delta-aminolevulinic acid dehydrase activity Catalysis of the reaction: 2 5-aminolevulinate = 2 H(2)O + H(+) + porphobilinogen. GO:0004654 polyribonucleotide nucleotidyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004654 MetaCyc:2.7.7.8-RXN|EC:2.7.7.8|RHEA:22096 polyribonucleotide phosphorylase activity|nucleoside diphosphate:polynucleotidyl transferase activity|polyribonucleotide:phosphate nucleotidyltransferase activity|polynucleotide phosphorylase activity Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate. GO:0004651 polynucleotide 5'-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004651 MetaCyc:POLYNUCLEOTIDE-5-PHOSPHATASE-RXN|RHEA:11008|EC:3.1.3.33|Reactome:R-HSA-77078 polynucleotide 5'-phosphohydrolase activity|polynucleotide 5'-triphosphatase activity|5'-polynucleotidase activity Catalysis of the reaction: 5'-phosphopolynucleotide + H2O = polynucleotide + phosphate. CHEBI:137949 O(3)-(beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl)-L-serine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137949 GO:0004650 polygalacturonase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004650 MetaCyc:RXN-2103|EC:3.2.1.15 endo-polygalacturonase activity|endo-D-galacturonase activity|endopolygalacturonase activity|pectolase activity|pectin depolymerase activity|poly-alpha-1,4-galacturonide glycanohydrolase activity|pectin polygalacturonase activity|poly(1,4-alpha-D-galacturonide) glycanohydrolase activity|endogalacturonase activity|pectinase activity|pectin hydrolase activity Catalysis of the random hydrolysis of (1->4)-alpha-D-galactosiduronic linkages in pectate and other galacturonans. CHEBI:137948 N-carbamoyl-D-methionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137948 CHEBI:137942 alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[alpha-N-acetylneuraminosyl-(2->6)]-N-acetyl-beta-D-galactosaminide(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137942 CHEBI:137941 beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-glucosaminide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137941 CHEBI:137945 N-carbamoyl-L-methionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137945 PO:0025128 phyllome primordium biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025128 phyllome primordia (exact, plural)|portion of phyllome primordium tissue (exact)|フィロム原基（可視的） (Japanese, exact)|primordio del filoma (Spanish, exact) A primordium (PO:0025127) that develops from a phyllome anlagen (PO:0025430) and is part of a shoot apex (PO:0000037) and is committed to the development of a phyllome (PO:0006001). PO:0025127 primordium biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025127 portion of primordial tissue (exact)|primordia (exact, plural)|primordio (Spanish, exact)|portion of primordium tissue (exact)|原基（可視的） (Japanese, exact) A portion of meristem tissue (PO:0009013) that has as parts protoderm (PO:0006210) and sub-epidermal meristematic tissue and is committed to the development of a particular plant structure (PO:0009011). CHEBI:18584 (5-L-glutamyl)-L-amino acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_18584 PO:0025123 embryo sac egg cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025123 胚嚢卵細胞 (Japanese, exact)|oocélula del saco embrionario (Spanish, exact) A plant egg cell (PO:0020094) that is part of an egg apparatus (PO:0020096). GO:0004624 obsolete secreted phospholipase A2 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004624 secreted phospholipase A2 activity OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a fatty acid anion. GO:0004623 phospholipase A2 activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0004623 Reactome:R-HSA-1482759|Reactome:R-HSA-1482816|Reactome:R-HSA-1482900|Reactome:R-HSA-1482778|Reactome:R-HSA-1482679|Reactome:R-HSA-1482887|Reactome:R-HSA-1482856|Reactome:R-HSA-1482897|MetaCyc:PHOSPHOLIPASE-A2-RXN|Reactome:R-HSA-1602417|Reactome:R-HSA-1482884|Reactome:R-HSA-1482771|Reactome:R-HSA-1602446|Reactome:R-HSA-1482907|RHEA:15801|Reactome:R-HSA-1482825|Reactome:R-HSA-1482868|Reactome:R-HSA-1602399|Reactome:R-HSA-1602374|Reactome:R-HSA-1482745|Reactome:R-HSA-1602398|EC:3.1.1.4|Reactome:R-HSA-1602368|Reactome:R-HSA-1482656|Reactome:R-HSA-1482604|Reactome:R-HSA-8848484|Reactome:R-HSA-1482776|Reactome:R-HSA-1602377 cytosolic phospholipase A2 activity|secreted phospholipase A2 activity|phosphatidolipase activity|phosphatidylcholine 2-acylhydrolase activity|phosphatidase activity|phospholipase A|lecithinase A activity Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. GO:0004626 obsolete cytosolic phospholipase A2 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004626 cytosolic phospholipase A2 activity OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a fatty acid anion. PO:0025121 pollen sperm cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025121 花粉精子細胞 (Japanese, exact)|célula espermática polínica (Spanish, exact) A plant sperm cell (PO:0000084) that is part of the pollen (PO:0025281). GO:0004625 obsolete calcium-dependent secreted phospholipase A2 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004625 calcium-dependent secreted phospholipase A2 activity OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a fatty acid anion. GO:0004620 phospholipase activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0004620 Reactome:R-HSA-6786650|Reactome:R-HSA-6792445|EC:3.1.1.- Catalysis of the hydrolysis of a glycerophospholipid. GO:0004622 lysophospholipase activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0004622 Reactome:R-HSA-1482612|Reactome:R-HSA-6814766|Reactome:R-HSA-6814778|Reactome:R-HSA-1482685|Reactome:R-HSA-8847912|RHEA:15177|EC:3.1.1.5|Reactome:R-HSA-1482629|Reactome:R-HSA-1482545|Reactome:R-HSA-6814254|MetaCyc:LYSOPHOSPHOLIPASE-RXN|Reactome:R-HSA-1482571|Reactome:R-HSA-1482696 2-lysophosphatidylcholine acylhydrolase activity|lysophosphatidase activity|lysophospholipase A1|lysolecithinase activity|lysophopholipase L2|lysophosphatidylcholine hydrolase activity|lecitholipase activity|phosphatidase B|lecithinase B activity|phospholipase B activity Catalysis of the reaction: 2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate. GO:0004621 glycosylphosphatidylinositol phospholipase D activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004621 MetaCyc:GLYCOPROTEIN-PHOSPHOLIPASE-D-RXN|Reactome:R-HSA-8940388|RHEA:10832|EC:3.1.4.50 phosphatidylinositol-glycan-specific phospholipase D activity|GPI-PLD activity|phosphatidylinositol phospholipase D activity|glycoprotein phospholipase D activity|phosphatidylinositol-specific phospholipase D activity|glycoprotein-phosphatidylinositol phosphatidohydrolase activity Catalysis of the reaction: glycoprotein phosphatidylinositol + H2O = phosphatidate + glycoprotein inositol. CHEBI:137917 4-hydroxy-17beta-estradiol 4-O-(beta-D-glucuronide) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137917 CHEBI:137911 4-hydroxy-17beta-estradiol 3-O-(beta-D-glucuronide) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137911 PO:0025117 plant anatomical space biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025117 lacunae (narrow)|lumen (narrow)|lumina (narrow)|lacuna (narrow)|espacio anatómico vegetal (Spanish, exact)|植物 解剖学（形態）的空間 (Japanese, exact) An anatomical space that is part of a plant. GO:0004628 obsolete calcium-independent cytosolic phospholipase A2 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004628 calcium-independent cytosolic phospholipase A2 activity OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a fatty acid anion. GO:0004627 obsolete calcium-dependent cytosolic phospholipase A2 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004627 calcium-dependent cytosolic phospholipase A2 activity OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a fatty acid anion. GO:0004629 phospholipase C activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004629 Reactome:R-HSA-5362553|MetaCyc:PHOSPHOLIPASE-C-RXN|Reactome:R-HSA-399998|Reactome:R-HSA-114688|Reactome:R-HSA-114689|Reactome:R-HSA-398193|EC:3.1.4.3|Reactome:R-HSA-1112666 phosphatidase C|lecithinase C activity|lipophosphodiesterase C Catalysis of the reaction: a phospholipid + H2O = 1,2-diacylglycerol + a phosphatidate. GO:0004635 phosphoribosyl-AMP cyclohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004635 MetaCyc:HISTCYCLOHYD-RXN|EC:3.5.4.19|RHEA:20049|KEGG_REACTION:R04037 1-(5-phospho-D-ribosyl)-AMP 1,6-hydrolase activity|phosphoribosyladenosine monophosphate cyclohydrolase activity|PRAMP-cyclohydrolase activity Catalysis of the reaction: 1-(5-phosphonatoribosyl)-5'-AMP + H(2)O = 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide. GO:0004634 phosphopyruvate hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004634 MetaCyc:2PGADEHYDRAT-RXN|EC:4.2.1.11|Reactome:R-HSA-71660|RHEA:10164|Reactome:R-HSA-70494 gamma-enolase activity|2-phospho-D-glycerate-hydrolase activity|2-phospho-D-glycerate hydro-lyase activity|phosphoenolpyruvate hydratase activity|14-3-2-protein|enolase activity|2-phospho-D-glycerate hydro-lyase (phosphoenolpyruvate-forming)|nervous-system specific enolase|2-phosphoglyceric dehydratase activity|2-phosphoglycerate dehydratase activity|2-phosphoglycerate enolase activity Catalysis of the reaction: 2-phospho-D-glycerate = phosphoenolpyruvate + H2O. GO:0004637 phosphoribosylamine-glycine ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004637 KEGG_REACTION:R04144|RHEA:17453|Reactome:R-HSA-73814|MetaCyc:GLYRIBONUCSYN-RXN|EC:6.3.4.13 5-phospho-D-ribosylamine:glycine ligase (ADP-forming)|GAR synthetase activity|phosphoribosylglycineamide synthetase activity|GAR|GARS activity|glycinamide ribonucleotide synthetase activity|5'-phosphoribosylglycinamide synthetase activity|glycineamide ribonucleotide synthetase activity|phosphoribosylglycinamide synthetase activity|2-amino-N-ribosylacetamide 5'-phosphate kinosynthase activity Catalysis of the reaction: 5-phospho-D-ribosylamine + ATP + glycine = N(1)-(5-phospho-D-ribosyl)glycinamide + ADP + 2 H(+) + phosphate. GO:0004636 phosphoribosyl-ATP diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004636 MetaCyc:HISTPRATPHYD-RXN|RHEA:22828|EC:3.6.1.31|KEGG_REACTION:R04035 phosphoribosyladenosine triphosphate pyrophosphatase activity|1-(5-phosphoribosyl)-ATP diphosphohydrolase activity|phosphoribosyl-ATP pyrophosphatase activity Catalysis of the reaction: 1-(5-phospho-D-ribosyl)-ATP + H(2)O = 1-(5-phosphonatoribosyl)-5'-AMP + diphosphate + H(+). GO:0004631 phosphomevalonate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004631 RHEA:16341|Reactome:R-HSA-191422|MetaCyc:PHOSPHOMEVALONATE-KINASE-RXN|KEGG_REACTION:R03245|EC:2.7.4.2 5-phosphomevalonate kinase activity|mevalonate phosphate kinase activity|ATP:5-phosphomevalonate phosphotransferase activity|mevalonate-5-phosphate kinase activity|mevalonic acid phosphate kinase activity|ATP:(R)-5-phosphomevalonate phosphotransferase activity Catalysis of the reaction: (R)-5-phosphomevalonate + ATP = (R)-5-diphosphomevalonate + ADP + H(+). GO:0004630 phospholipase D activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0004630 Reactome:R-HSA-2029471|Reactome:R-HSA-1483142|Reactome:R-HSA-1483182|MetaCyc:PHOSCHOL-RXN|RHEA:14445|EC:3.1.4.4 lipophosphodiesterase II activity|lecithinase D activity|phosphatidylcholine phosphatidohydrolase activity|choline phosphatase activity Catalysis of the reaction: a phosphatidylcholine + H2O = choline + a phosphatidate. GO:0004633 phosphopantothenoylcysteine decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004633 RHEA:16793|MetaCyc:P-PANTOCYSDECARB-RXN|Reactome:R-HSA-196840|EC:4.1.1.36|KEGG_REACTION:R03269 N-[(R)-4'-phosphopantothenoyl]-L-cysteine carboxy-lyase activity|N-((R)-4'-phosphopantothenoyl)-L-cysteine carboxy-lyase activity|4-phosphopantothenoyl-L-cysteine decarboxylase activity|PPC-decarboxylase activity|N-[(R)-4'-phosphopantothenoyl]-L-cysteine carboxy-lyase (pantotheine-4'-phosphate-forming)|4-phosphopantotheoylcysteine decarboxylase activity Catalysis of the reaction: N-[(R)-4-phosphonatopantothenoyl]-L-cysteinate + H(+) = CO(2) + pantetheine 4'-phosphate. GO:0004632 phosphopantothenate--cysteine ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004632 RHEA:19397|Reactome:R-HSA-196753|MetaCyc:P-PANTOCYSLIG-RXN|EC:6.3.2.5 phosphopantothenoylcysteine synthetase activity|phosphopantothenate-cysteine ligase activity|(R)-4'-phosphopantothenate:L-cysteine ligase activity Catalysis of the reaction: CTP + (R)-4'-phosphopantothenate + L-cysteine = CMP + diphosphate + (R)-4'-phosphopantothenoyl-L-cysteine. Cysteine can be replaced by some of its derivatives. CHEBI:137927 CDP-alpha-D-glucose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137927 CHEBI:137921 lithocholic acid 3-O-(beta-D-glucuronide) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137921 CHEBI:137924 2-hydroxyestrone 3-O-(beta-D-glucuronide) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137924 CHEBI:137923 5'-end ribonucleotide(1-) residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137923 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004639 KEGG_REACTION:R04591|MetaCyc:SAICARSYN-RXN|RHEA:22628|Reactome:R-HSA-73805|EC:6.3.2.6 4-(N-succinocarboxamide)-5-aminoimidazole synthetase activity|5-aminoimidazole-4-N-succinocarboxamide ribonucleotide synthetase activity|SAICAR synthetase activity|phosphoribosylaminoimidazolesuccinocarboxamide synthetase activity|phosphoribosylaminoimidazole-succinocarboxamide synthetase activity|5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate:L-aspartate ligase (ADP-forming)|4-[(N-succinylamino)carbonyl]-5-aminoimidazole ribonucleotide synthetase activity|PurC|SAICARs activity|SAICAR synthase activity|4-((N-succinylamino)carbonyl)-5-aminoimidazole ribonucleotide synthetase activity|phosphoribosylaminoimidazole-succinocarboxamide synthase activity Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate + ATP = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate + ADP + 2 H(+) + phosphate. GO:0004638 phosphoribosylaminoimidazole carboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004638 MetaCyc:AIRCARBOXY-RXN|KEGG_REACTION:R04209|EC:4.1.1.21|Reactome:R-HSA-73806|RHEA:10792 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate carboxy-lyase activity|AIR carboxylase activity|5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate carboxy-lyase [5-amino-1-(5-phospho-D-ribosyl)imidazole-forming]|ADE2|class II PurE|5-amino-1-ribosylimidazole 5-phosphate carboxylase activity|5-phosphoribosyl-5-aminoimidazole carboxylase activity|1-(5-phosphoribosyl)-5-amino-4-imidazolecarboxylate carboxy-lyase activity Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + 2 H(+) = 5-amino-1-(5-phospho-D-ribosyl)imidazole + CO(2). GO:0004602 glutathione peroxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004602 Reactome:R-HSA-2161959|Reactome:R-HSA-2161999|Reactome:R-HSA-6799695|Reactome:R-HSA-3341277|Reactome:R-HSA-3341397|RHEA:16833|Reactome:R-HSA-3323013|Reactome:R-HSA-2161946|EC:1.11.1.9|Reactome:R-HSA-71676|Reactome:R-HSA-2161791|Reactome:R-HSA-3343700|MetaCyc:GLUTATHIONE-PEROXIDASE-RXN reduced glutathione peroxidase activity|non-selenium glutathione peroxidase activity|glutathione:hydrogen-peroxide oxidoreductase activity|selenium-glutathione peroxidase activity|GSH peroxidase activity Catalysis of the reaction: 2 glutathione + hydrogen peroxide = oxidized glutathione + 2 H2O. GO:0004601 peroxidase activity biolink:MolecularActivity go-plus goslim_metagenomics http://purl.obolibrary.org/obo/GO_0004601 EC:1.11.1.-|Reactome:R-HSA-1222346|Reactome:R-HSA-2559639|Reactome:R-HSA-6789126|Reactome:R-HSA-3341296|Reactome:R-HSA-140359|KEGG_REACTION:R03532|Reactome:R-HSA-6789031|MetaCyc:PEROXID-RXN|Reactome:R-HSA-209815|Reactome:R-HSA-2309773|Reactome:R-HSA-8855490|Reactome:R-HSA-5631885|Reactome:R-HSA-8933635|Reactome:R-HSA-350901|Reactome:R-HSA-209840|Reactome:R-HSA-209973|Reactome:R-HSA-209925 horseradish peroxidase (HRP)|protoheme peroxidase|lactoperoxidase activity|peroxidase reaction|scopoletin peroxidase|donor:hydrogen-peroxide oxidoreductase activity|secretory plant peroxidase activity|bacterial catalase-peroxidase activity|extensin peroxidase|MPO|myeloperoxidase activity|verdoperoxidase|heme peroxidase|thiocyanate peroxidase|guaiacol peroxidase|pyrocatechol peroxidase|oxyperoxidase activity|japanese radish peroxidase|eosinophil peroxidase activity Catalysis of the reaction: donor + hydrogen peroxide = oxidized donor + 2 H2O. GO:0004604 phosphoadenylyl-sulfate reductase (thioredoxin) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004604 MetaCyc:1.8.4.8-RXN|RHEA:11724|EC:1.8.4.8|KEGG_REACTION:R02021 PAPS reductase, thioredoxin-dependent activity|phosphoadenosine-phosphosulfate reductase activity|adenosine 3',5'-bisphosphate,sulfite:thioredoxin-disulfide oxidoreductase (3'-phosphoadenosine-5'-phosphosulfate-forming)|PAPS reductase activity|phosphoadenylyl-sulphate reductase (thioredoxin) activity|PAdoPS reductase activity|thioredoxin:adenosine 3'-phosphate 5'-phosphosulfate reductase activity|3'-phosphoadenylylsulfate reductase activity|PAPS sulfotransferase activity|adenosine 3',5'-bisphosphate,sulfite:oxidized-thioredoxin oxidoreductase (3'-phosphoadenosine-5'-phosphosulfate-forming)|thioredoxin:3'-phospho-adenylylsulfate reductase activity Catalysis of the reaction: adenosine 3',5'-diphosphate + H(+) + sulfite + thioredoxin disulfide = 3'-phospho-5'-adenylyl sulfate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin; 3'-phosphoadenosine 5'-phosphosulfate is also known as PAPS. GO:0004603 phenylethanolamine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004603 EC:2.1.1.28|MetaCyc:2.1.1.28-RXN|RHEA:12176|Reactome:R-HSA-209903 norepinephrine methyltransferase activity|norepinephrine N-methyltransferase activity|S-adenosyl-L-methionine:phenylethanolamine N-methyltransferase activity|noradrenaline N-methyltransferase activity|phenethanolamine methyltransferase activity|phenethanolamine N-methyltransferase activity|noradrenalin N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + phenylethanolamine = S-adenosyl-L-homocysteine + N-methylphenylethanolamine. GO:0004600 obsolete cyclophilin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004600 cyclophilin OBSOLETE. A protein to which cyclosporin A (an immunosuppressant) binds. Possesses peptidyl-prolyl isomerase activity. CHEBI:231086 Octadec-9-enoic acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_231086 CHEBI:300 (R)-(+)-alpha-terpineol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_300 GO:0004609 phosphatidylserine decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004609 Reactome:R-HSA-1483212|RHEA:20828|EC:4.1.1.65|MetaCyc:PHOSPHASERDECARB-RXN|KEGG_REACTION:R02055 phosphatidyl-L-serine carboxy-lyase activity|phosphatidyl-L-serine carboxy-lyase (phosphatidylethanolamine-forming)|PS decarboxylase activity Catalysis of the reaction: H(+) + phosphatidyl-L-serine = CO(2) + phosphatidylethanolamine. GO:0004606 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004606 GO:0004605 phosphatidate cytidylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004605 Reactome:R-HSA-1483121|Reactome:R-HSA-1483165|MetaCyc:CDPDIGLYSYN-RXN|RHEA:16229|EC:2.7.7.41 CDP diglyceride pyrophosphorylase activity|CDP-diglyceride synthetase activity|CTP:1,2-diacylglycerophosphate-cytidyl transferase activity|DAG synthetase activity|CTP-diacylglycerol synthetase activity|phosphatidic acid cytidylyltransferase activity|phosphatidate cytidyltransferase activity|CDP-DG|CDP-diacylglycerol synthase activity|CDP-diacylglyceride synthetase activity|cytidine diphosphoglyceride pyrophosphorylase activity|CTP:phosphatidate cytidylyltransferase activity|CDP-diglyceride synthase activity|CDP-diglyceride pyrophosphorylase activity|CDP-diglyceride diphosphorylase activity Catalysis of the reaction: CTP + phosphatidate = diphosphate + CDP-diacylglycerol. UBERON:0006127 funiculus of spinal cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006127 spinal cord funiculus|white column of spinal cord A funiculus of neuraxis that is part of a spinal cord. GO:0004608 phosphatidylethanolamine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004608 EC:2.1.1.17|MetaCyc:2.1.1.17-RXN|KEGG_REACTION:R02056|RHEA:11164|Reactome:R-HSA-1483174 phosphatidylethanolamine-N-methylase activity|phosphatidylethanolamine methyltransferase activity|phosphatidylethanolamine-S-adenosylmethionine methyltransferase activity|PEMT|S-adenosyl-L-methionine:phosphatidylethanolamine N-methyltransferase activity|lipid methyl transferase activity|LMTase activity Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidylethanolamine = S-adenosyl-L-homocysteine + H(+) + phosphatidyl-N-methylethanolamine. GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004607 Reactome:R-HSA-264695|RHEA:21204|EC:2.3.1.43|MetaCyc:2.3.1.43-RXN phospholipid--cholesterol acyltransferase activity|phosphatidylcholine:sterol O-acyltransferase activity|lecithin:cholesterol acyltransferase activity|LCAT (lecithin-cholesterol acyltransferase)|lecithin--cholesterol acyltransferase activity|LCAT activity Catalysis of the reaction: phosphatidylcholine + a sterol = a sterol ester + 1-acylglycerophosphocholine. GO:0004613 phosphoenolpyruvate carboxykinase (GTP) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004613 Reactome:R-HSA-70241|MetaCyc:4.1.1.32-RXN|Reactome:R-HSA-372819|EC:4.1.1.32|RHEA:10388 GTP:oxaloacetate carboxy-lyase (transphosphorylating)|phosphoenolpyruvate carboxylase (GTP)|phosphoenolpyruvic carboxykinase|phosphopyruvate (guanosine triphosphate) carboxykinase activity|phosphoenolpyruvic carboxylase (GTP)|phosphopyruvate carboxylase (GTP)|GTP:oxaloacetate carboxy-lyase (adding GTP; phosphoenolpyruvate-forming)|phosphoenolpyruvic carboxykinase (GTP) Catalysis of the reaction: GTP + oxaloacetate = GDP + phosphoenolpyruvate + CO2. GO:0004612 phosphoenolpyruvate carboxykinase (ATP) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004612 EC:4.1.1.49|MetaCyc:PEPCARBOXYKIN-RXN|RHEA:18617|KEGG_REACTION:R00341 PEPK|ATP:oxaloacetate carboxy-lyase (transphosphorylating)|phosphoenolpyruvate carboxylase (ATP)|phosphoenolpyruvic carboxykinase|phosphopyruvate carboxykinase|phosphopyruvate carboxylase (ATP)|PEPCK (ATP)|ATP:oxaloacetate carboxy-lyase (transphosphorylating; phosphoenolpyruvate-forming)|phosphopyruvate carboxykinase (adenosine triphosphate) Catalysis of the reaction: ATP + oxaloacetate = ADP + CO(2) + H(+) + phosphoenolpyruvate. GO:0004615 phosphomannomutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004615 RHEA:11140|Reactome:R-HSA-3781926|Reactome:R-HSA-446201|MetaCyc:PHOSMANMUT-RXN|KEGG_REACTION:R01818|EC:5.4.2.8 alpha-D-mannose 1,6-phosphomutase activity|mannose phosphomutase activity|D-mannose 1,6-phosphomutase activity|phosphomannose mutase activity Catalysis of the reaction: alpha-D-mannose 1-phosphate = D-mannose 6-phosphate. GO:0004614 phosphoglucomutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004614 EC:5.4.2.2|Reactome:R-HSA-9638125|Reactome:R-HSA-5609939|Reactome:R-HSA-70272|Reactome:R-HSA-9638127|RHEA:23536|Reactome:R-HSA-70427|MetaCyc:PHOSPHOGLUCMUT-RXN glucose phosphomutase activity|phosphoglucose mutase activity|alpha-D-glucose 1,6-phosphomutase activity Catalysis of the reaction: alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. GO:0004611 phosphoenolpyruvate carboxykinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004611 EC:4.1.1.32 PEPCK activity|phosphopyruvate carboxylase activity|PEP carboxykinase activity Catalysis of the reaction: source of phosphate + oxaloacetate = phosphoenolpyruvate + CO2 + other reaction products. GO:0004610 phosphoacetylglucosamine mutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004610 EC:5.4.2.3|KEGG_REACTION:R08193|MetaCyc:PHOSACETYLGLUCOSAMINEMUT-RXN|RHEA:23804|Reactome:R-HSA-446185 N-acetyl-alpha-D-glucosamine 1,6-phosphomutase activity|N-acetyl-D-glucosamine 1,6-phosphomutase activity|acetylaminodeoxyglucose phosphomutase activity|acetylglucosamine phosphomutase activity|N-acetylglucosamine-phosphate mutase activity|phospho-N-acetylglucosamine mutase activity Catalysis of the reaction: N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate. CHEBI:137907 2-hydroxy-17beta-estradiol 2-O-(beta-D-glucuronide) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137907 GO:0004617 phosphoglycerate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004617 RHEA:12641|Reactome:R-HSA-977348|MetaCyc:PGLYCDEHYDROG-RXN|EC:1.1.1.95 3PHP reductase activity|glycerate-1,3-phosphate dehydrogenase activity|3-phosphoglycerate dehydrogenase activity|alpha-KG reductase activity|glycerate 3-phosphate dehydrogenase activity|D- and L-HGA|SerA|3-phosphoglycerate:NAD+ 2-oxidoreductase activity|D-3-phosphoglycerate dehydrogenase activity|alphaKG reductase activity|phosphoglycerate oxidoreductase activity|3-phosphoglyceric acid dehydrogenase activity|3-phospho-D-glycerate:NAD+ 2-oxidoreductase activity|PGDH activity|alpha-phosphoglycerate dehydrogenase activity|SerA 3PG dehydrogenase activity|D-3-phosphoglycerate:NAD+ oxidoreductase activity|phosphoglyceric acid dehydrogenase activity Catalysis of the reaction: 3-phosphoglycerate + NAD+ = 3-phosphohydroxypyruvate + NADH + H+. GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004616 Reactome:R-HSA-71299|EC:1.1.1.44|MetaCyc:6PGLUCONDEHYDROG-RXN|RHEA:10116 6-phospho-D-gluconate dehydrogenase activity|6-phosphogluconic dehydrogenase activity|phosphogluconic acid dehydrogenase activity|6-phospho-D-gluconate:NADP+ 2-oxidoreductase (decarboxylating)|6-phosphogluconate dehydrogenase (decarboxylating)|6PGD activity|6-phosphogluconic carboxylase activity Catalysis of the reaction: 6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH + H+. GO:0004619 phosphoglycerate mutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004619 EC:5.4.2.1|Reactome:R-HSA-71445|Reactome:R-HSA-71654|MetaCyc:3PGAREARR-RXN|RHEA:15901 monophosphoglycerate mutase activity|GriP mutase|D-phosphoglycerate 2,3-phosphomutase activity|PGA mutase activity|phosphoglycerate phosphomutase activity|diphosphoglycomutase|phosphoglyceromutase activity|PGM|monophosphoglyceromutase activity|PGAM activity|bisphosphoglyceromutase|MPGM Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D-glycerate. GO:0004618 phosphoglycerate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004618 EC:2.7.2.3|Reactome:R-HSA-71850|MetaCyc:PHOSGLYPHOS-RXN|Reactome:R-HSA-70486|KEGG_REACTION:R01512|RHEA:14801 glycerate 3-phosphate kinase activity|3-phosphoglyceric kinase activity|3-phosphoglycerate kinase activity|ATP:D-3-phosphoglycerate 1-phosphotransferase activity|phosphoglyceric kinase activity|3-phosphoglycerate phosphokinase activity|3-PGK|phosphoglyceric acid kinase activity|glycerophosphate kinase activity|phosphoglycerokinase activity|PGK|3-phosphoglyceric acid kinase activity|3-phosphoglyceric acid phosphokinase activity|ATP-3-phospho-D-glycerate-1-phosphotransferase activity|ATP:3-phospho-D-glycerate 1-phosphotransferase activity Catalysis of the reaction: 3-phospho-D-glycerate + ATP = 3-phospho-D-glyceroyl phosphate + ADP + H(+). PO:0025166 papilla cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025166 乳頭細胞 (Japanese, exact)|célula papilosa (Spanish, exact) An epidermal pavement cell with a short protuberance. PO:0025165 shoot epidermal cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025165 célula epidérmica del epiblasto (epiblastema) (Spanish, exact)|シュート表皮 細胞 (Japanese, exact) An epidermal cell that is part of a shoot epidermis. PO:0025164 root epidermal cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025164 根表皮細胞 (Japanese, exact)|célula epidérmica de la raíz (Spanish, exact) An epidermal cell that is part of a root epidermis. PO:0025162 multicellular trichome biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025162 non-glandular multicelluar trichome (narrow)|non-secretory multicellular trichome (narrow)|tricoma multicelular (Spanish, exact)|多細胞毛（毛茸、糸状体） (Japanese, exact) A portion of plant tissue (PO:0009007) that forms a non-sclerified outgrowth from the epidermis (PO:0005679). PO:0025158 bract epidermis biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025158 epidermis de la bráctea (Spanish, exact)|苞表皮 (Japanese, exact) A portion of phyllome epidermis (PO:0025157) that is part of a bract (PO:0009055). PO:0025157 phyllome epidermis biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0025157 epidermis del filoma (Spanish, exact)|フィロム表皮 (Japanese, exact) A portion of shoot system epidermis (PO:0006035) that is part of a phyllome (PO:0006001). PR:000029968 somatotropin hormone family member biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000029968 fam:GH1 A protein that is a standalone version of the Hormone_1 domain (Pfam:PF00103). In the immature form, the domain is preceded by a signal peptide. CHEBI:147345 (2S)-hydroperoxy fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_147345 CHEBI:147340 (2R)-2-hydroperoxy fatty acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_147340 CHEBI:147341 fumigermin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_147341 CHEBI:147344 (2R)-hydroperoxy fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_147344 CHEBI:147343 2-hydroperoxy fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_147343 GO:0038016 insulin receptor internalization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038016 insulin receptor endocytosis A receptor-mediated endocytosis process that results in the movement of an insulin receptor from the plasma membrane to the inside of the cell. GO:0014049 positive regulation of glutamate secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014049 up-regulation of glutamate secretion|upregulation of glutamate secretion|up regulation of glutamate secretion|activation of glutamate secretion|stimulation of glutamate secretion Any process that activates or increases the frequency, rate or extent of the controlled release of glutamate. GO:0014048 regulation of glutamate secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014048 Any process that modulates the frequency, rate or extent of the controlled release of glutamate. GO:0038015 positive regulation of insulin receptor signaling pathway by insulin receptor internalization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038015 positive regulation of insulin receptor signalling pathway by insulin receptor internalization Any process in which internalization of an insulin receptor activates or increases the frequency, rate or extent of the insulin receptor signaling pathway. Endocytosis of activated receptors can concentrate receptors within endosomes and allow the insulin receptor to phosphorylate substrates that are spatially distinct from those accessible at the plasma membrane. GO:0014047 glutamate secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014047 The controlled release of glutamate by a cell. The glutamate is the most abundant excitatory neurotransmitter in the nervous system. GO:0038018 Wnt receptor catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038018 Frizzled degradation|Wnt receptor catabolism|negative regulation of Wnt receptor signaling pathway by Wnt receptor degradation|Wnt receptor degradation|Wnt receptor breakdown The chemical reactions and pathways resulting in the breakdown of a Wnt receptor. Internalized Wnt receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation. GO:0014046 dopamine secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014046 The regulated release of dopamine by a cell. Dopamine is a catecholamine and a precursor of adrenaline and noradrenaline. It acts as a neurotransmitter in the central nervous system but it is also produced peripherally and acts as a hormone. GO:0038017 Wnt receptor internalization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038017 Wnt receptor endocytosis A receptor-mediated endocytosis process that results in the movement of a Wnt receptor from the plasma membrane to the inside of the cell. GO:0038019 Wnt receptor recycling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038019 Frizzled recycling The process that results in the return of a Wnt receptor to an active state at the plasma membrane. An active state is when the receptor is ready to receive a Wnt signal. Internalized Wnt receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation. GO:0014041 regulation of neuron maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014041 Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change. GO:0014040 positive regulation of Schwann cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014040 upregulation of Schwann cell differentiation|stimulation of Schwann cell differentiation|up-regulation of Schwann cell differentiation|activation of Schwann cell differentiation|up regulation of Schwann cell differentiation Any process that activates or increases the frequency, rate or extent of Schwann cell differentiation. GO:0038010 positive regulation of signal transduction by receptor internalization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038010 positive regulation of signaling pathway by receptor endocytosis Any process in which the internalization of a signaling receptor activates or increases the frequency, rate or extent of signal transduction. Receptor internalization can enhance signaling by concentrating signaling molecules in one location, or by moving a ligand-activated receptor to the location of downstream signaling proteins. Endosomes for example can serve as important intracellular signaling platforms. GO:0038012 negative regulation of Wnt signaling pathway by Wnt receptor internalization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038012 ligand-dependent internalization of Frizzled|negative regulation of Wnt receptor signalling pathway by Wnt receptor internalization|negative regulation of Wnt receptor signaling pathway by Wnt receptor endocytosis|negative regulation of Wnt receptor signaling pathway by Wnt receptor internalization|negative regulation of Wnt-activated signaling pathway by Wnt receptor internalization Any process in which internalization of a Wnt receptor stops, prevents, or reduces the frequency, rate or extent of Wnt signal transduction. GO:0014045 establishment of endothelial blood-brain barrier biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014045 establishment of endothelial BBB|establishment of endothelial blood/brain barrier Establishment of the endothelial barrier between the blood and the brain. The endothelial cells in the brain capillaries are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier. GO:0014044 Schwann cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014044 The process aimed at the progression of a Schwann cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function. GO:0038011 negative regulation of signal transduction by receptor internalization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038011 negative regulation of signaling pathway by receptor endocytosis Any process in which internalization of a signaling receptor stops, prevents, or reduces the frequency, rate or extent of signal transduction. Receptor internalization can attenuate or reduce the strength of signaling by reducing the concentration of cell surface receptors available to ligands. GO:0038014 negative regulation of insulin receptor signaling pathway by insulin receptor internalization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038014 agonist-stimulated insulin receptor internalization|negative regulation of insulin receptor signalling pathway by insulin receptor internalization Any process in which internalization of an insulin receptor stops, prevents, or reduces the frequency, rate or extent of insulin receptor signal transduction. Internalization of insulin in association with its receptor clears insulin from the circulation and is necessary for subsequent insulin dissociation from the receptor and insulin degradation. GO:0014043 negative regulation of neuron maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014043 down regulation of neuron maturation|downregulation of neuron maturation|down-regulation of neuron maturation|inhibition of neuron maturation Any process that stops, prevents, or reduces the frequency, rate or extent of neuron maturation. GO:0014042 positive regulation of neuron maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014042 upregulation of neuron maturation|up regulation of neuron maturation|activation of neuron maturation|stimulation of neuron maturation|up-regulation of neuron maturation Any process that activates or increases the frequency, rate or extent of neuron maturation. GO:0038013 positive regulation of Wnt signaling pathway by Wnt receptor internalization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038013 positive regulation of Wnt receptor signalling pathway by Wnt receptor endocytosis|positive regulation of Wnt receptor signaling pathway by Frizzled internalization|positive regulation of Wnt receptor signaling pathway by LRP6 internalization|positive regulation of Wnt-activated signaling pathway by Wnt receptor internalization|positive regulation of Wnt receptor signaling pathway by Wnt receptor internalization Any process in which internalization of a Wnt receptor activates or increases the frequency, rate or extent of the Wnt signaling pathway. CHEBI:147335 1-phosphatidyl-1D-myo-inositol-3-phosphate anion derivative biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_147335 CHEBI:147334 1-phosphatidyl-1D-myo-inositol anion derivative biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_147334 GO:0038005 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0038005 GO:0038004 epidermal growth factor receptor ligand maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038004 peptide bond cleavage involved in epidermal growth factor receptor ligand maturation|peptide bond cleavage involved in EGFR ligand maturation|EGFR ligand maturation by peptide bond cleavage|EGFR ligand maturation|EGFR ligand processing|epidermal growth factor receptor ligand processing Any process leading to the attainment of the full functional capacity of a ligand for an epidermal growth factor receptor. The ligand is functional when it can bind to and activate an epidermal growth factor receptor. GO:0014059 regulation of dopamine secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014059 Any process that modulates the frequency, rate or extent of the regulated release of dopamine. GO:0038007 netrin-activated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038007 netrin-activated signalling pathway|netrin-mediated signaling pathway|netrin signaling pathway|netrin-activated signal transduction pathway A series of molecular events initiated by the binding of a netrin protein to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Netrins can act as chemoattractant signals for some cells and chemorepellent signals for others. Netrins also have roles outside of cell and axon guidance. GO:0014058 negative regulation of acetylcholine secretion, neurotransmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014058 down regulation of acetylcholine secretion|downregulation of acetylcholine secretion|down-regulation of acetylcholine secretion|inhibition of acetylcholine secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of acetylcholine. GO:0014057 positive regulation of acetylcholine secretion, neurotransmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014057 upregulation of acetylcholine secretion|up regulation of acetylcholine secretion|activation of acetylcholine secretion|stimulation of acetylcholine secretion|up-regulation of acetylcholine secretion Any process that activates or increases the frequency, rate or extent of the regulated release of acetylcholine. GO:0038006 netrin receptor activity involved in chemoattraction biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038006 netrin receptor activity involved in positive chemotaxis|attractive netrin receptor activity Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to contribute to the directed movement of a motile cell towards a higher concentration of netrin. GO:0038009 regulation of signal transduction by receptor internalization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038009 regulation of signaling pathway by receptor endocytosis Any process that modulates the frequency, rate or extent of signal transduction by the movement of a signaling receptor from the plasma membrane to the inside of the cell. Receptor internalization can have a positive or negative effect on a signaling pathway. GO:0038008 TRAF-mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038008 tumor necrosis factor receptor-associated factor signaling|TRAF-mediated signalling|tumor necrosis factor receptor-associated factor signal transduction|TRAF signaling|TRAF-mediated intracellular signaling|TRAF-mediated signaling The intracellular process in which a signal is passed on to downstream components within the cell via a tumor necrosis factor receptor-associated factor (TRAF). TRAFs are directly or indirectly recruited to the intracellular domains of cell surface receptors, and engage other signaling proteins to transfer the signal from a cell surface receptor to other intracellular signaling components. GO:0014052 regulation of gamma-aminobutyric acid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014052 regulation of GABA secretion Any process that modulates the frequency, rate or extent of the regulated release of gamma-aminobutyric acid. GO:0014051 gamma-aminobutyric acid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014051 GABA secretion The regulated release of gamma-aminobutyric acid by a cell or a tissue. The gamma-aminobutyric acid is the principal inhibitory neurotransmitter in the brain but is also found in several extraneural tissues. GO:0014050 negative regulation of glutamate secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014050 downregulation of glutamate secretion|down-regulation of glutamate secretion|inhibition of glutamate secretion|down regulation of glutamate secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of glutamate. GO:0038001 paracrine signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038001 paracrine signalling The transfer of information from one cell to another, where the signal travels from the signal-producing cell to the receiving cell by passive diffusion or bulk flow in intercellular fluid. The signaling cell and the receiving cell are usually in the vicinity of each other. GO:0014056 regulation of acetylcholine secretion, neurotransmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014056 Any process that modulates the frequency, rate or extent of the regulated release of acetylcholine. GO:0014055 acetylcholine secretion, neurotransmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014055 The regulated release of acetylcholine by a cell. The acetylcholine acts as a neurotransmitter that acts in both the peripheral nervous system (PNS) and central nervous system (CNS). GO:0038003 opioid receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038003 opioid receptor signalling pathway The series of molecular signals generated as a consequence of an opioid receptor binding to one of its physiological ligands. GO:0014054 positive regulation of gamma-aminobutyric acid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014054 up regulation of gamma-aminobutyric acid secretion|activation of gamma-aminobutyric acid secretion|stimulation of gamma-aminobutyric acid secretion|up-regulation of gamma-aminobutyric acid secretion|positive regulation of GABA secretion|upregulation of gamma-aminobutyric acid secretion Any process that activates or increases the frequency, rate or extent of the regulated release of gamma-aminobutyric acid. GO:0038002 endocrine signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038002 endocrine signalling The transfer of information from one cell to another, where an endocrine hormone is transported from the signal-producing cell to the receiving cell via the circulatory system (via blood, lymph or cerebrospinal fluid). The signaling cell and the receiving cell are often distant to each other. GO:0014053 negative regulation of gamma-aminobutyric acid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014053 down regulation of gamma-aminobutyric acid secretion|downregulation of gamma-aminobutyric acid secretion|down-regulation of gamma-aminobutyric acid secretion|inhibition of gamma-aminobutyric acid secretion|negative regulation of GABA secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of gamma-aminobutyric acid. CHEBI:137998 O-{S-[4-(gamma-L-glutamylamino)butanoyl]pantetheine-4'-phosphoryl}serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137998 GO:0014027 secondary neural tube rod cavitation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014027 medullary rod cavitation The process of medullary cavitation, which is the formation of a lumen in the medullary cord during secondary neurulation, producing the neural tube. CHEBI:137997 O-[S-4-(aminobutanoyl)pantetheine-4'-phosphoryl]serine zwitterionic residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137997 GO:0014026 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0014026 CHEBI:137996 O-[S-(gamma-L-glutamyl)pantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137996 GO:0014025 neural keel formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014025 The formation of a thickened region of the neurectoderm that is roughly triangular in cross section. The neural keel develops from the neural plate and develops into the neural rod. Neural keel formation occurs during primary neurulation in teleosts. CHEBI:137995 2-ethyl-4-hydroxy-5-methyl-3(2H)-furanone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137995 GO:0014024 neural rod cavitation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014024 The process of rod cavitation, which is the formation of a lumen in the neural rod during primary neurulation, producing the neural tube. GO:0014029 neural crest formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014029 The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes. GO:0014028 notochord formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014028 The formation of the notochord from the chordamesoderm. The notochord is composed of large cells packed within a firm connective tissue sheath and is found in all chordates at the ventral surface of the neural tube. In vertebrates, the notochord contributes to the vertebral column. CHEBI:137999 O-[S-4-(gamma-L-glutamylamino)-(2S)-2-hydroxybutanoylpantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137999 CHEBI:137990 (beta-Asp-Arg)n-Asp(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137990 CHEBI:137994 (2E)-2-ethylidene-4-hydroxy-5-methyl-3(2H)-furanone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137994 GO:0014023 neural rod formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014023 The formation of a solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts. GO:0014022 neural plate elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014022 The process in which the neural plate is shaped by the intrinsic movement of the epidermal and neural plate regions. GO:0014021 secondary neural tube formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014021 neural rod formation|medullary cord formation|medullary cord biosynthesis|secondary neurulation The formation of the neural tube by coalescence of mesenchymal cells followed by their conversion to epithelial cells to form a solid cord that subsequently hollows out (cavitates) to create a hollow tube. Secondary neurulation is the typical mechanism of formation of the neural tube posterior to the posterior neuropore in mammals. GO:0014020 primary neural tube formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014020 primary neurulation|primary neural tube morphogenesis The formation of the neural tube from an epithelial cell sheet (the neuroepithelium or neural plate). In primary neurulation, the cells surrounding the neural plate direct the neural plate cells to proliferate, invaginate, and pinch off from the surface to form a hollow epithelial tube. Primary neurulation is the typical mechanism of formation of the anterior neural tube. CHEBI:137991 beta-Asp-Arg zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137991 GO:0014038 regulation of Schwann cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014038 Any process that modulates the frequency, rate or extent of Schwann cell differentiation. GO:0014037 Schwann cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014037 The process in which a relatively unspecialized cell acquires the specialized features of a Schwann cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function. GO:0014036 neural crest cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014036 The process in which a cell becomes capable of differentiating autonomously into a neural crest cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. GO:0014035 neural crest cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014035 The process in which a cell becomes capable of differentiating autonomously into a neural crest cell regardless of its environment; upon determination, the cell fate cannot be reversed. GO:0014039 negative regulation of Schwann cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014039 down-regulation of Schwann cell differentiation|downregulation of Schwann cell differentiation|down regulation of Schwann cell differentiation|inhibition of Schwann cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of Schwann cell differentiation. GO:0014030 mesenchymal cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014030 The process in which a cell becomes committed to become a mesenchymal cell. GO:0014034 neural crest cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014034 The process in which a cell becomes committed to become a neural crest cell. GO:0014033 neural crest cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014033 The process in which a relatively unspecialized cell acquires specialized features of a neural crest cell. GO:0014032 neural crest cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014032 The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. GO:0014031 mesenchymal cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014031 The process aimed at the progression of a mesenchymal cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. GO:0004689 phosphorylase kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004689 MetaCyc:2.7.11.19-RXN|EC:2.7.11.19|Reactome:R-HSA-453337|Reactome:R-HSA-71588|Reactome:R-HSA-71541 phosphorylase kinase (phosphorylating) activity|phosphorylase kinase, intrinsic catalyst activity|glycogen phosphorylase kinase activity|ATP:phosphorylase-b phosphotransferase activity|dephosphophosphorylase kinase activity|phosphorylase B kinase activity|PHK|STK17 Catalysis of the reaction: 4 ATP + 2 phosphorylase b = 4 ADP + phosphorylase a. GO:0004686 elongation factor-2 kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004686 MetaCyc:2.7.11.20-RXN|EC:2.7.11.20|RHEA:21436 eEF2K|EF2K|elongation factor 2 kinase activity|eEF2 kinase activity|Ca/CaM-kinase III activity|ATP:elongation factor 2 phosphotransferase activity|STK19|CaM kinase III activity|calmodulin-dependent protein kinase III activity|eEF-2 kinase activity|eukaryotic elongation factor 2 kinase activity Catalysis of the reaction: ATP + [elongation factor 2] = ADP + [elongation factor 2] phosphate. GO:0004685 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004685 GO:0004688 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004688 GO:0004687 myosin light chain kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004687 RHEA:22004|MetaCyc:2.7.11.18-RXN|Reactome:R-HSA-5668978|EC:2.7.11.18|Reactome:R-HSA-445813 MLCK|smooth-muscle-myosin-light-chain kinase activity|MLCkase activity|myosin kinase activity|myosin light-chain kinase (phosphorylating) activity|myosin light-chain kinase|myosin light chain protein kinase activity|myosin-light-chain kinase activity|ATP:myosin-light-chain O-phosphotransferase|calcium/calmodulin-dependent myosin light chain kinase activity|ATP:myosin-light-chain O-phosphotransferase activity|STK18|myosin light-chain kinase (phosphorylating)|myosin light-chain kinase activity Catalysis of the reaction: ATP + myosin-light-chain = ADP + myosin-light-chain phosphate. GO:0004682 obsolete protein kinase CK2 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004682 protein kinase CK2 activity|casein kinase II, catalytic activity|protein kinase CK2, intrinsic catalyst activity|casein kinase II activity OBSOLETE. Catalysis of the reaction: casein + ATP = phosphocasein + ADP. GO:0004681 obsolete casein kinase I activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004681 casein kinase I activity OBSOLETE. (Was not defined before being made obsolete). GO:0004684 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004684 GO:0004683 calmodulin-dependent protein kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004683 Reactome:R-HSA-9619355|Reactome:R-HSA-416320|MetaCyc:2.7.11.17-RXN|Reactome:R-HSA-9618750|EC:2.7.11.17|Reactome:R-HSA-9619125|Reactome:R-HSA-111912|Reactome:R-HSA-442749|Reactome:R-HSA-111915|Reactome:R-HSA-9619478|Reactome:R-HSA-9617583|Reactome:R-HSA-9619367|Reactome:R-HSA-9619783|Reactome:R-HSA-9006992 Ca2+/calmodulin-dependent protein kinase kinase beta activity|multifunctional calcium- and calmodulin-regulated protein kinase activity|calmodulin-dependent protein kinase I activity|microtubule-associated protein 2 kinase activity|Ca2+/calmodulin-dependent protein kinase 1 activity|Ca2+/calmodulin-dependent protein kinase II activity|CaMKKbeta|Ca2+/calmodulin-dependent protein kinase kinase activity|CaMKII|CaM kinase activity|calmodulin-dependent kinase II activity|ATP:caldesmon O-phosphotransferase activity|calcium/calmodulin-dependent protein kinase type II activity|CaM-regulated serine/threonine kinase activity|multifunctional calcium/calmodulin regulated protein kinase activity|calcium/calmodulin-dependent protein kinase activity|calmodulin regulated protein kinase activity|Ca2+/calmodulin-dependent microtubule-associated protein 2 kinase activity|Ca2+/calmodulin-dependent protein kinase IV activity|caldesmon kinase (phosphorylating) activity|ATP:protein phosphotransferase (Ca2+/calmodulin-dependent) activity|calcium- and calmodulin-dependent protein kinase activity|CaMKKalpha|CaMKI|CaM kinase II activity|Ca2+/CaM-dependent kinase activity|CAM PKII|Ca2+/calmodulin-dependent protein kinase activity|CaMKIV|STK20 Calmodulin-dependent catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate. GO:0004680 obsolete casein kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004680 casein kinase activity OBSOLETE. (Was not defined before being made obsolete). CHEBI:137976 S-acetyl-O-[2'-(5-phosphoribosyl)-3'-dephospho-CoA]-L-serine(3-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137976 GO:0014005 microglia development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014005 microglial cell development The process aimed at the progression of a microglial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. GO:0014004 microglia differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014004 microglial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a microglial cell. Microglia are glial cells that act as the immune cells of the central nervous system. They form part of the supporting structure of this system. GO:0014003 oligodendrocyte development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014003 oligodendrocyte cell development The process aimed at the progression of an oligodendrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An oligodendrocyte is a type of glial cell involved in myelinating the axons in the central nervous system. GO:0014002 astrocyte development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014002 astrocyte cell development The process aimed at the progression of an astrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function. GO:0014009 glial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014009 glia proliferation The multiplication or reproduction of glial cells by cell division, resulting in the expansion of their population. Glial cells exist throughout the nervous system, and include Schwann cells, astrocytes, and oligodendrocytes among others. GO:0014008 positive regulation of microglia differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014008 positive regulation of microglial cell differentiation|up-regulation of microglia differentiation|upregulation of microglia differentiation|up regulation of microglia differentiation|activation of microglia differentiation|stimulation of microglia differentiation Any process that activates, maintains or increases the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell. CHEBI:137979 D-galactosylglycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137979 GO:0014007 negative regulation of microglia differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014007 inhibition of microglia differentiation|negative regulation of microglial cell differentiation|down regulation of microglia differentiation|downregulation of microglia differentiation|down-regulation of microglia differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell. GO:0014006 regulation of microglia differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014006 regulation of microglial cell differentiation Any process that modulates the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell. CHEBI:147309 diarachidonoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_147309 GO:0014001 sclerenchyma cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014001 The process in which a relatively unspecialized cell acquires specialized features of a sclerenchyma cell. A sclerenchyma cell is a plant cell with thick lignified walls, normally dead at maturity and specialized for structural strength. Includes fiber cells, that are greatly elongated; and sclereids, that are more isodiametric. Intermediate types exist. Cells may or may not be devoid of protoplasm at maturity. Cell form and size are variable. GO:0004697 protein kinase C activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004697 Reactome:R-HSA-5625784|Reactome:R-HSA-1433508|Reactome:R-HSA-198314|Reactome:R-HSA-5623667|Reactome:R-HSA-429698|Reactome:R-HSA-450550|Reactome:R-HSA-2179413|Reactome:R-HSA-450533|Reactome:R-HSA-9010681|Reactome:R-HSA-5218823|Reactome:R-HSA-9632858|Reactome:R-HSA-9021357|Reactome:R-HSA-5218805|Reactome:R-HSA-374664|Reactome:R-HSA-927889|Reactome:R-HSA-909552|Reactome:R-HSA-8934446|Reactome:R-HSA-751040|Reactome:R-HSA-2730863|Reactome:R-HSA-5671749|Reactome:R-HSA-9626817|Reactome:R-HSA-5229194|MetaCyc:2.7.11.13-RXN|Reactome:R-HSA-5138432|Reactome:R-HSA-74615|EC:2.7.11.13|Reactome:R-HSA-193703 protein kinase Cepsilon activity|nPKCepsilon|PKCdelta|diacylglycerol-activated phospholipid-dependent protein kinase C activity|diacylglycerol-activated phospholipid-dependent PKC activity|STK24|PKC|Pkc1p|cPKC|nPKCtheta|PKCepsilon|cPKCgamma|PKCzeta|PKCgamma|nPKCdelta|PKC activity|nPKC|ATP:protein phosphotransferase (diacylglycerol-dependent) activity|cPKCalpha|PKCbeta|nPKCeta|PKCalpha|cPKCbeta Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylglycerol. GO:0004696 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004696 GO:0004699 calcium-independent protein kinase C activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004699 Reactome:R-HSA-5607740 calcium-independent PKC activity|novel protein kinase C activity Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylglycerol but not calcium. GO:0004698 calcium-dependent protein kinase C activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004698 Reactome:R-HSA-416639|Reactome:R-HSA-114684|Reactome:R-HSA-421007|EC:2.7.11.13|Reactome:R-HSA-114683 conventional protein kinase C activity|calcium-dependent PKC activity Calcium-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. GO:0004693 cyclin-dependent protein serine/threonine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004693 Reactome:R-HSA-5692755|Reactome:R-HSA-2245218|Reactome:R-HSA-380278|Reactome:R-HSA-68944|Reactome:R-HSA-9008412|Reactome:R-HSA-2468293|Reactome:R-HSA-180047|Reactome:R-HSA-2984220|Reactome:R-HSA-6793661|Reactome:R-HSA-2990882|Reactome:R-HSA-3788705|Reactome:R-HSA-187916|Reactome:R-HSA-9686521|Reactome:R-HSA-1912391|Reactome:R-HSA-2468287|Reactome:R-HSA-9009282|Reactome:R-HSA-69227|Reactome:R-HSA-174251|Reactome:R-HSA-5244669|Reactome:R-HSA-4086410|Reactome:R-HSA-187959|Reactome:R-HSA-4088024|Reactome:R-HSA-2172183|Reactome:R-HSA-2220971|MetaCyc:2.7.11.22-RXN|Reactome:R-HSA-6805109|Reactome:R-HSA-6797606|Reactome:R-HSA-1226095|Reactome:R-HSA-2430533|Reactome:R-HSA-187948|Reactome:R-HSA-2294600|Reactome:R-HSA-69005|Reactome:R-HSA-5195402|Reactome:R-HSA-9624800|Reactome:R-HSA-174132|Reactome:R-HSA-69756|Reactome:R-HSA-1226094|EC:2.7.11.22|Reactome:R-HSA-2514854|Reactome:R-HSA-188390|Reactome:R-HSA-174079|Reactome:R-HSA-187520|Reactome:R-HSA-69754|Reactome:R-HSA-174122 cyclin-dependent protein kinase activity|CDK|neuronal cdc2-like kinase activity|cyclin-dependent kinase-2 activity|cyclin D-cdk6 kinase activity|cdc2 kinase activity|cyclin-dependent kinase-4 activity|CDK, catalytic subunit activity|cyclin-A associated kinase activity|ATP:cyclin phosphotransferase activity|Cdk-activating protein kinase activity|cdk-activating kinase activity|cyclin E kinase activity|cyclin-dependent kinase activity|CDK activity|D-type cyclin kinase activity|cyclin-dependent kinase 6 activity|cyclin D-dependent kinase activity|cyclin-dependent protein kinase, intrinsic catalyst activity Cyclin-dependent catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. GO:0004692 cGMP-dependent protein kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004692 Reactome:R-HSA-418442|MetaCyc:2.7.11.12-RXN|Reactome:R-HSA-1475422|Reactome:R-HSA-1497853|Reactome:R-HSA-418549|EC:2.7.11.12 ATP:protein phosphotransferase (cGMP-dependent) activity|PKG 1beta|PKG|STK23|guanosine 3':5'-cyclic monophosphate-dependent protein kinase activity|PKG 1alpha|3':5'-cyclic GMP-dependent protein kinase activity|PKG II|cGMP-dependent protein kinase ibeta activity cGMP dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. GO:0004695 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004695 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004694 Catalysis of the reaction: ATP + [eukaryotic translation initiation factor 2 alpha subunit] = ADP + [eukaryotic translation initiation factor 2 alpha subunit] phosphate. CHEBI:7719 ochratoxin A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_7719 GO:0004691 cAMP-dependent protein kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004691 Reactome:R-HSA-5687088|Reactome:R-HSA-5610741|Reactome:R-HSA-5610720|Reactome:R-HSA-913451|Reactome:R-HSA-432232|Reactome:R-HSA-163773|Reactome:R-HSA-177284|Reactome:R-HSA-163676|Reactome:R-HSA-5617182|Reactome:R-HSA-177275|MetaCyc:2.7.11.11-RXN|Reactome:R-HSA-5617179|EC:2.7.11.11|Reactome:R-HSA-5610717|Reactome:R-HSA-163672 cAMP-dependent protein kinase, intrinsic catalyst activity|3',5' cAMP-dependent protein kinase activity|STK22|PKA C|ATP:protein phosphotransferase (cAMP-dependent) activity|protein kinase A activity|AMPK|PKA|3',5'-cAMP-dependent protein kinase activity|adenosine 3',5'-cyclophosphate-dependent protein kinase activity|cyclic AMP-dependent protein kinase activity cAMP-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. GO:0004690 cyclic nucleotide-dependent protein kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004690 cNMP-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. GO:0014016 neuroblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014016 The process in which a relatively unspecialized cell acquires specialized features of a neuroblast. There are at least four stages through which the pluripotent cells of epiblast or blastula become neuroblasts. CHEBI:137987 19-hydroxyprostaglandin I2(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137987 GO:0014015 positive regulation of gliogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014015 upregulation of gliogenesis|up regulation of gliogenesis|activation of gliogenesis|stimulation of gliogenesis|up-regulation of gliogenesis Any process that activates or increases the frequency, rate or extent of gliogenesis, the formation of mature glia. CHEBI:137986 (beta-Asp-Arg)n zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137986 GO:0014014 negative regulation of gliogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014014 down regulation of gliogenesis|downregulation of gliogenesis|down-regulation of gliogenesis|inhibition of gliogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of gliogenesis, the formation of mature glia. GO:0014013 regulation of gliogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014013 Any process that modulates the frequency, rate or extent of gliogenesis, the formation of mature glia. CHEBI:137984 methylated secondary ammonium ion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137984 GO:0014019 neuroblast development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014019 The process aimed at the progression of a neuroblast over time, from initial commitment of the cell to a specific state, to the mature neuroblast. It does not include processes where the neuroblast turns into a glial cell or a neuron. GO:0014018 neuroblast fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014018 The process in which a cell becomes capable of differentiating autonomously into a neuroblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. GO:0014017 neuroblast fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014017 The process in which the developmental fate of a cell becomes restricted such that it will differentiate into a neuroblast. CHEBI:137983 methylated tertiary amine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137983 GO:0014012 peripheral nervous system axon regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014012 axon regeneration in peripheral nervous system The regrowth of axons outside the central nervous system (outside the brain and spinal cord) following an axonal injury. CHEBI:137982 tertiary ammonium ion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137982 GO:0014011 Schwann cell proliferation involved in axon regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014011 The multiplication or reproduction of Schwann cells by cell division, resulting in the expansion of their population in response to an axonal lesion. The newly generated Schwann cells support subsequent axon regeneration in the peripheral nervous system. CHEBI:137981 5-amino-1-(5-phosphonato-beta-D-ribosyl)imidazol-3-ium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137981 GO:0014010 Schwann cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0014010 The multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system. CHEBI:137980 metalloid atom biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137980 GO:0004668 protein-arginine deiminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004668 EC:3.5.3.15|RHEA:18089|Reactome:R-HSA-1183128|Reactome:R-HSA-3247569|MetaCyc:PROTEIN-ARGININE-DEIMINASE-RXN protein-L-arginine iminohydrolase activity|peptidylarginine deiminase activity Catalysis of the reaction: protein L-arginine + H2O = protein L-citrulline + NH3. This reaction is calcium-dependent. GO:0004667 prostaglandin-D synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004667 RHEA:10600|KEGG_REACTION:R02266|Reactome:R-HSA-2161701|Reactome:R-HSA-2161620|MetaCyc:PROSTAGLANDIN-D-SYNTHASE-RXN|EC:5.3.99.2 prostaglandin-R-prostaglandin D isomerase activity|(5,13)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate D-isomerase activity|prostaglandin-H2 D-isomerase activity|prostaglandin D2 synthase activity|PGH-PGD isomerase activity|PGD2 synthase activity Catalysis of the reaction: prostaglandin H(2) = prostaglandin D(2). GO:0004664 prephenate dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004664 MetaCyc:PREPHENATEDEHYDRAT-RXN|EC:4.2.1.51|RHEA:21648 prephenate hydro-lyase (decarboxylating)|prephenate hydro-lyase (decarboxylating; phenylpyruvate-forming) Catalysis of the reaction: prephenate = phenylpyruvate + H2O + CO2. GO:0004663 Rab geranylgeranyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004663 EC:2.5.1.60|MetaCyc:RXN-3701|MetaCyc:2.5.1.60-RXN type II protein geranyl-geranyltransferase activity|GGTaseII activity|geranylgeranyl-diphosphate,geranylgeranyl-diphosphate:protein-cysteine geranyltransferase activity|GGTase-II activity|Rab-protein geranylgeranyltransferase activity|protein geranylgeranyltransferase type II activity|RabGGTase activity Catalysis of the reaction: 2 geranylgeranyl diphosphate + protein-cysteine = 2 S-geranylgeranyl-protein + 2 diphosphate. This reaction is the formation of two thioether linkages between the C-1 atom of the geranylgeranyl groups and two cysteine residues within the terminal sequence motifs XXCC, XCXC or CCXX. Known substrates include Ras-related GTPases of a single family and the Rab family. GO:0004666 prostaglandin-endoperoxide synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004666 MetaCyc:PROSTAGLANDIN-ENDOPEROXIDE-SYNTHASE-RXN|Reactome:R-HSA-140355|Reactome:R-HSA-2309787|EC:1.14.99.1|RHEA:23728 prostaglandin endoperoxide synthetase activity|(PG)H synthase activity|prostaglandin synthetase activity|fatty acid cyclooxygenase activity|PG synthetase activity|(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate,hydrogen-donor:oxygen oxidoreductase activity|prostaglandin synthase activity|prostaglandin G/H synthase activity Catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O. GO:0004665 prephenate dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004665 KEGG_REACTION:R01730|RHEA:21640|MetaCyc:PREPHENATE-DEHYDROGENASE-NADP+-RXN|EC:1.3.1.13 prephenate (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity|prephenate:NADP+ oxidoreductase (decarboxylating) Catalysis of the reaction: NADP(+) + prephenate = (4-hydroxyphenyl)pyruvate + CO(2) + NADPH. GO:0004660 protein farnesyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004660 RHEA:13345|MetaCyc:2.5.1.58-RXN|Reactome:R-HSA-2530501|Reactome:R-HSA-9647978|EC:2.5.1.58 CAAX farnesyltransferase activity|farnesyl-diphosphate:protein-cysteine farnesyltransferase activity|FTase activity|protein-cysteine farnesyltransferase activity Catalysis of the reaction: farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate. GO:0004662 CAAX-protein geranylgeranyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004662 MetaCyc:RXN-3701|MetaCyc:2.5.1.60-RXN|EC:2.5.1.59 GGTaseI activity|geranylgeranyl-diphosphate:protein-cysteine geranyltransferase activity|type I protein geranyl-geranyltransferase activity|geranylgeranyltransferase type I activity|GGTase-I activity|protein geranylgeranyltransferase type I Catalysis of the reaction: geranylgeranyl diphosphate + protein-cysteine = S-geranylgeranyl-protein + diphosphate. This reaction is the formation of a thioether linkage between the C-1 atom of the geranylgeranyl group and a cysteine residue fourth from the C-terminus of the protein. The protein substrates have the C-terminal sequence CA1A2X, where the terminal residue, X, is preferably leucine and A2 should not be aromatic. Known substrates include most g-subunits of heterotrimeric G proteins and Ras-related GTPases such as members of the Ras and Rac/Rho families. GO:0004661 protein geranylgeranyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004661 protein-cysteine geranylgeranyltransferase activity Catalysis of the covalent addition of a geranylgeranyl (20-carbon isoprenoid) group via thioether linkages to a cysteine residue at or near the C terminus of a protein. CHEBI:137954 N(6)-[(E)-but-2-enoyl]-L-lysine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137954 CHEBI:137952 UDP-2,3-diacyl-alpha-D-glucosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137952 CHEBI:137955 N(6)-butyryl-L-lysine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137955 CHEBI:137950 O(3)-(beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl)-L-threonine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137950 GO:0004679 AMP-activated protein kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004679 EC:2.7.11.11|Reactome:R-HSA-5673768|Reactome:R-HSA-6805470|Reactome:R-HSA-200423|Reactome:R-HSA-1592244|Reactome:R-HSA-447074|Reactome:R-HSA-163691|Reactome:R-HSA-380927 AMPK activity|5'-AMP-activated protein kinase activity|SNF1A/AMP-activated protein kinase activity Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of AMP. GO:0004678 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004678 GO:0004675 transmembrane receptor protein serine/threonine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004675 Reactome:R-HSA-198732|EC:2.7.11.30|Reactome:R-HSA-170868|RHEA:18673|Reactome:R-HSA-201476|MetaCyc:2.7.11.30-RXN activin receptor kinase activity|STK13|receptor type II serine/threonine protein kinase activity|TGF-beta kinase activity|receptor type I serine/threonine protein kinase activity|receptor serine/threonine protein kinase activity|receptor protein serine/threonine kinase activity|ATP:receptor-protein phosphotransferase activity Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. GO:0004674 protein serine/threonine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004674 Reactome:R-HSA-5357831|Reactome:R-HSA-165766|Reactome:R-HSA-165726|Reactome:R-HSA-9610153|Reactome:R-HSA-5635841|Reactome:R-HSA-3857328|Reactome:R-HSA-166286|Reactome:R-HSA-5683801|Reactome:R-HSA-211164|Reactome:R-HSA-5692779|Reactome:R-HSA-5624473|Reactome:R-HSA-198731|Reactome:R-HSA-202459|Reactome:R-HSA-195283|Reactome:R-HSA-450325|Reactome:R-HSA-2400001|Reactome:R-HSA-3371567|Reactome:R-HSA-6805285|Reactome:R-HSA-448955|Reactome:R-HSA-9683664|Reactome:R-HSA-5610718|Reactome:R-HSA-2430535|Reactome:R-HSA-8948039|Reactome:R-HSA-2028679|Reactome:R-HSA-5632672|Reactome:R-HSA-3222006|Reactome:R-HSA-8878054|Reactome:R-HSA-381091|Reactome:R-HSA-200421|Reactome:R-HSA-5674496|Reactome:R-HSA-109822|Reactome:R-HSA-9633008|Reactome:R-HSA-165758|Reactome:R-HSA-1549526|Reactome:R-HSA-199299|Reactome:R-HSA-5357477|Reactome:R-HSA-1168635|Reactome:R-HSA-2396007|Reactome:R-HSA-202222|Reactome:R-HSA-6801675|Reactome:R-HSA-209087|Reactome:R-HSA-5607732|Reactome:R-HSA-2028589|Reactome:R-HSA-442739|Reactome:R-HSA-446701|Reactome:R-HSA-6802935|Reactome:R-HSA-432110|Reactome:R-HSA-5684096|Reactome:R-HSA-9648883|Reactome:R-HSA-442832|Reactome:R-HSA-9032751|Reactome:R-HSA-5682026|Reactome:R-HSA-2028673|Reactome:R-HSA-5693540|Reactome:R-HSA-399950|Reactome:R-HSA-1362270|Reactome:R-HSA-5357472|Reactome:R-HSA-199935|Reactome:R-HSA-975874|Reactome:R-HSA-9013978|Reactome:R-HSA-2029454|Reactome:R-HSA-198371|Reactome:R-HSA-9612980|Reactome:R-HSA-8868567|Reactome:R-HSA-8878050|Reactome:R-HSA-9627089|Reactome:R-HSA-9648089|Reactome:R-HSA-170126|Reactome:R-HSA-109862|Reactome:R-HSA-199917|Reactome:R-HSA-198599|Reactome:R-HSA-2028555|Reactome:R-HSA-5685156|Reactome:R-HSA-8856813|Reactome:R-HSA-5218814|Reactome:R-HSA-3769394|Reactome:R-HSA-5260201|Reactome:R-HSA-5686578|Reactome:R-HSA-8940100|Reactome:R-HSA-8853419|Reactome:R-HSA-2730876|Reactome:R-HSA-75820|Reactome:R-HSA-2399969|Reactome:R-HSA-5672828|Reactome:R-HSA-156678|Reactome:R-HSA-2028598|Reactome:R-HSA-399951|Reactome:R-HSA-6805276|Reactome:R-HSA-2060328|Reactome:R-HSA-5687094|Reactome:R-HSA-419644|Reactome:R-HSA-195318|Reactome:R-HSA-975865|Reactome:R-HSA-2028675|Reactome:R-HSA-5672973|Reactome:R-HSA-5218916|Reactome:R-HSA-166284|Reactome:R-HSA-202500|Reactome:R-HSA-5672010|Reactome:R-HSA-75028|Reactome:R-HSA-1445144|Reactome:R-HSA-2990880|Reactome:R-HSA-2029469|Reactome:R-HSA-450827|Reactome:R-HSA-3857329|Reactome:R-HSA-202437|Reactome:R-HSA-419087|Reactome:R-HSA-8942836|Reactome:R-HSA-1168641|Reactome:R-HSA-451152|Reactome:R-HSA-419083|Reactome:R-HSA-5690250|Reactome:R-HSA-1168638|Reactome:R-HSA-188350|Reactome:R-HSA-6811454|Reactome:R-HSA-111919|Reactome:R-HSA-163418|Reactome:R-HSA-1449597|Reactome:R-HSA-193647|Reactome:R-HSA-176298|Reactome:R-HSA-4332358|Reactome:R-HSA-198613|Reactome:R-HSA-6802943|Reactome:R-HSA-8854908|Reactome:R-HSA-193705|Reactome:R-HSA-5632670|Reactome:R-HSA-1181156|Reactome:R-HSA-5693598|Reactome:R-HSA-109860|Reactome:R-HSA-3858480|Reactome:R-HSA-1458463|Reactome:R-HSA-170087|Reactome:R-HSA-392752|Reactome:R-HSA-8853444|Reactome:R-HSA-6805479|Reactome:R-HSA-3772435|Reactome:R-HSA-975861|Reactome:R-HSA-399952|Reactome:R-HSA-399944|Reactome:R-HSA-5610722|Reactome:R-HSA-9673346|Reactome:R-HSA-5679205|Reactome:R-HSA-5683792|Reactome:R-HSA-9694293|Reactome:R-HSA-2399966|Reactome:R-HSA-5687090|Reactome:R-HSA-170076|Reactome:R-HSA-198669|Reactome:R-HSA-4793911|Reactome:R-HSA-2529020|Reactome:R-HSA-8868344|Reactome:R-HSA-164151|Reactome:R-HSA-9032863|Reactome:R-HSA-8868573|Reactome:R-HSA-5668947|Reactome:R-HSA-9008480|Reactome:R-HSA-8933446|Reactome:R-HSA-8850945|Reactome:R-HSA-2028583|Reactome:R-HSA-5683425|Reactome:R-HSA-448948|Reactome:R-HSA-6805103|Reactome:R-HSA-5666160|EC:2.7.11.-|Reactome:R-HSA-8868118|Reactome:R-HSA-5672008|Reactome:R-HSA-5624492|Reactome:R-HSA-6805126|Reactome:R-HSA-166119|Reactome:R-HSA-912470|Reactome:R-HSA-3000310|Reactome:R-HSA-6804276|Reactome:R-HSA-429016|Reactome:R-HSA-5692768|Reactome:R-HSA-8868666|Reactome:R-HSA-5686704|Reactome:R-HSA-2399988|Reactome:R-HSA-9632868|Reactome:R-HSA-5685242|Reactome:R-HSA-5693536|Reactome:R-HSA-3371435|Reactome:R-HSA-165162|Reactome:R-HSA-9009208|Reactome:R-HSA-442724|Reactome:R-HSA-450499|Reactome:R-HSA-156682|Reactome:R-HSA-1592233|Reactome:R-HSA-5671763|Reactome:R-HSA-199839|Reactome:R-HSA-9645535|Reactome:R-HSA-2028670|Reactome:R-HSA-198609|Reactome:R-HSA-5687101|Reactome:R-HSA-109702|Reactome:R-HSA-199929|Reactome:R-HSA-419197|Reactome:R-HSA-3132737|Reactome:R-HSA-6804955|Reactome:R-HSA-198621|Reactome:R-HSA-5692775|Reactome:R-HSA-4332363|Reactome:R-HSA-5607742|Reactome:R-HSA-3249371|Reactome:R-HSA-198347|Reactome:R-HSA-2294580|Reactome:R-HSA-9008822|Reactome:R-HSA-2562526|Reactome:R-HSA-2399985|Reactome:R-HSA-201677|Reactome:R-HSA-3000327|Reactome:R-HSA-4411402|Reactome:R-HSA-8852306|Reactome:R-HSA-3928608|Reactome:R-HSA-2399941|Reactome:R-HSA-9656215|Reactome:R-HSA-3928577|Reactome:R-HSA-2399996|Reactome:R-HSA-156699|Reactome:R-HSA-6795290|Reactome:R-HSA-202541|Reactome:R-HSA-9624526|Reactome:R-HSA-2214351|Reactome:R-HSA-201691|Reactome:R-HSA-8877691|Reactome:R-HSA-6795460|Reactome:R-HSA-975180|Reactome:R-HSA-170116|Reactome:R-HSA-3371531|Reactome:R-HSA-5668984|Reactome:R-HSA-8944454|Reactome:R-HSA-374696|Reactome:R-HSA-2243938|Reactome:R-HSA-9023132|Reactome:R-HSA-450474|Reactome:R-HSA-9619843|Reactome:R-HSA-166245|Reactome:R-HSA-5693549|Reactome:R-HSA-5675868|Reactome:R-HSA-162363|Reactome:R-HSA-380272|Reactome:R-HSA-69891|Reactome:R-HSA-5627775|Reactome:R-HSA-112381|Reactome:R-HSA-5218826|Reactome:R-HSA-4551570|Reactome:R-HSA-6801666|Reactome:R-HSA-975170|Reactome:R-HSA-167084|Reactome:R-HSA-2399999|Reactome:R-HSA-75010|Reactome:R-HSA-5607726|Reactome:R-HSA-5684140|Reactome:R-HSA-2028591|Reactome:R-HSA-139918|Reactome:R-HSA-8870558|Reactome:R-HSA-934559|Reactome:R-HSA-9612509|Reactome:R-HSA-6805399|Reactome:R-HSA-5218906|Reactome:R-HSA-3928620|Reactome:R-HSA-9007539|Reactome:R-HSA-2028284|Reactome:R-HSA-349455|Reactome:R-HSA-975125|Reactome:R-HSA-975160|Reactome:R-HSA-6788392|Reactome:R-HSA-2993898|Reactome:R-HSA-381111|Reactome:R-HSA-9656214|Reactome:R-HSA-6802911|Reactome:R-HSA-5669250|Reactome:R-HSA-5682598|Reactome:R-HSA-195287|Reactome:R-HSA-199863|Reactome:R-HSA-5229343|Reactome:R-HSA-9634702|Reactome:R-HSA-170977|Reactome:R-HSA-936951|Reactome:R-HSA-168053|Reactome:R-HSA-2399977|Reactome:R-HSA-5693609|Reactome:R-HSA-5671919|Reactome:R-HSA-170055|Reactome:R-HSA-201717|Reactome:R-HSA-5635842|Reactome:R-HSA-5687121|Reactome:R-HSA-6799332|Reactome:R-HSA-377186|Reactome:R-HSA-450222|Reactome:R-HSA-937022|Reactome:R-HSA-5668545|Reactome:R-HSA-195300|Reactome:R-HSA-5213464|Reactome:R-HSA-2730856|Reactome:R-HSA-3229102|Reactome:R-HSA-8868340|Reactome:R-HSA-5228811|Reactome:R-HSA-199298|Reactome:R-HSA-3239019|Reactome:R-HSA-6805059|Reactome:R-HSA-2574840|Reactome:R-HSA-6795473|Reactome:R-HSA-5213466|Reactome:R-HSA-913996|Reactome:R-HSA-975878|Reactome:R-HSA-400382|Reactome:R-HSA-8852317|Reactome:R-HSA-5687183|Reactome:R-HSA-5693551|Reactome:R-HSA-5683964|Reactome:R-HSA-1638803|Reactome:R-HSA-6805640|Reactome:R-HSA-3928640|Reactome:R-HSA-5610732|Reactome:R-HSA-3928616|Reactome:R-HSA-8863007|Reactome:R-HSA-6800490|Reactome:R-HSA-163416|Reactome:R-HSA-174119|Reactome:R-HSA-2730868|Reactome:R-HSA-9619515|Reactome:R-HSA-165718|Reactome:R-HSA-429714|Reactome:R-HSA-5672978|Reactome:R-HSA-6805785|Reactome:R-HSA-6802926|Reactome:R-HSA-8948146|Reactome:R-HSA-5610730|Reactome:R-HSA-9681627|Reactome:R-HSA-3222020|Reactome:R-HSA-202510|Reactome:R-HSA-9604328|Reactome:R-HSA-450463|Reactome:R-HSA-918229|Reactome:R-HSA-5675194|Reactome:R-HSA-187688|Reactome:R-HSA-1358791|Reactome:R-HSA-5665868|Reactome:R-HSA-2029460|Reactome:R-HSA-163010|Reactome:R-HSA-451347|Reactome:R-HSA-9612501|Reactome:R-HSA-399939|Reactome:R-HSA-5693575|Reactome:R-HSA-9613530|Reactome:R-HSA-2243942|Reactome:R-HSA-9652165|Reactome:R-HSA-1632857|Reactome:R-HSA-5672948|Reactome:R-HSA-445072|Reactome:R-HSA-77071|Reactome:R-HSA-975853|Reactome:R-HSA-199895|Reactome:R-HSA-2399981|Reactome:R-HSA-195275|Reactome:R-HSA-3209160|Reactome:R-HSA-6799097|Reactome:R-HSA-8863895|Reactome:R-HSA-5082387|Reactome:R-HSA-6799246|Reactome:R-HSA-2466068|Reactome:R-HSA-9699579|Reactome:R-HSA-6804266|Reactome:R-HSA-156673|Reactome:R-HSA-8952289|Reactome:R-HSA-69608|Reactome:R-HSA-8863014|Reactome:R-HSA-2028629|Reactome:R-HSA-5578777|Reactome:R-HSA-5668932|Reactome:R-HSA-139908|Reactome:R-HSA-9648888|Reactome:R-HSA-9022314|Reactome:R-HSA-6798374|Reactome:R-HSA-5082405|Reactome:R-HSA-162657|Reactome:R-HSA-199910|Reactome:R-HSA-8868260|Reactome:R-HSA-165692|Reactome:R-HSA-198270|Reactome:R-HSA-9610156|Reactome:R-HSA-9662823|Reactome:R-HSA-1454699|Reactome:R-HSA-187949|Reactome:R-HSA-349444|Reactome:R-HSA-349426|Reactome:R-HSA-9012319|Reactome:R-HSA-2984258|Reactome:R-HSA-198640|Reactome:R-HSA-6814409|Reactome:R-HSA-3228469|Reactome:R-HSA-8948757|Reactome:R-HSA-156723|Reactome:R-HSA-5685230|Reactome:R-HSA-75809|Reactome:R-HSA-211583|Reactome:R-HSA-9626880|Reactome:R-HSA-2422927|Reactome:R-HSA-4411383|Reactome:R-HSA-165777|Reactome:R-HSA-2028661|Reactome:R-HSA-109823|Reactome:R-HSA-3229152|Reactome:R-HSA-933525|Reactome:R-HSA-2399982|Reactome:R-HSA-168140|Reactome:R-HSA-3928625|Reactome:R-HSA-428961|Reactome:R-HSA-446694|Reactome:R-HSA-69604|Reactome:R-HSA-6802919|Reactome:R-HSA-4332388|Reactome:R-HSA-6802973|Reactome:R-HSA-8939963|Reactome:R-HSA-167098|Reactome:R-HSA-1225894|Reactome:R-HSA-69685|Reactome:R-HSA-6810233|Reactome:R-HSA-8873929|Reactome:R-HSA-111970|Reactome:R-HSA-198611|Reactome:R-HSA-4608825|Reactome:R-HSA-174174|Reactome:R-HSA-4088134|Reactome:R-HSA-399978|Reactome:R-HSA-9633742|Reactome:R-HSA-211650|Reactome:R-HSA-198746|Reactome:R-HSA-5218821|Reactome:R-HSA-5684887|Reactome:R-HSA-937059|Reactome:R-HSA-6798372|Reactome:R-HSA-200143|Reactome:R-HSA-198756|Reactome:R-HSA-2730900|Reactome:R-HSA-2176475|Reactome:R-HSA-1181355|Reactome:R-HSA-1181149|Reactome:R-HSA-975134|Reactome:R-HSA-5675198|Reactome:R-HSA-2470508|Reactome:R-HSA-6802933|Reactome:R-HSA-9653503|Reactome:R-HSA-8863011|Reactome:R-HSA-5682983|Reactome:R-HSA-165182|Reactome:R-HSA-2730896|Reactome:R-HSA-8876446|Reactome:R-HSA-5682101|Reactome:R-HSA-5687086|Reactome:R-HSA-9610163|Reactome:R-HSA-5218854|Reactome:R-HSA-5694441|Reactome:R-HSA-2028635|Reactome:R-HSA-112342|Reactome:R-HSA-6799409|Reactome:R-HSA-450490|Reactome:R-HSA-176116|Reactome:R-HSA-389756|Reactome:R-HSA-3239014|Reactome:R-HSA-2399992|Reactome:R-HSA-2168079|Reactome:R-HSA-2984226|Reactome:R-HSA-5607722|Reactome:R-HSA-9620004|Reactome:R-HSA-9694620 protein-serine kinase activity|threonine-specific protein kinase activity|serine/threonine protein kinase activity|serine protein kinase activity|serine-specific protein kinase activity|protein phosphokinase activity|protein serine-threonine kinase activity|serine kinase activity|protein serine kinase activity|protein kinase (phosphorylating) activity|serine(threonine) protein kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. GO:0004677 DNA-dependent protein kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004677 DNA dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. GO:0004676 3-phosphoinositide-dependent protein kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004676 Reactome:R-HSA-437195 PDK activity|phosphatidylinositol-3-phosphate protein kinase activity Phosphatidylinositol-3-phosphate-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. GO:0004671 protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004671 Reactome:R-HSA-6788650|RHEA:21672|Reactome:R-HSA-9647977|KEGG_REACTION:R04496|MetaCyc:2.1.1.100-RXN|EC:2.1.1.100 prenylated protein carboxyl methyltransferase activity|S-adenosyl-L-methionine:protein-C-terminal-S-farnesyl-L-cysteine O-methyltransferase activity|isoprenylated protein methyltransferase activity|prenylcysteine carboxyl methyltransferase activity|farnesylated protein C-terminal O-methyltransferase activity|protein-S-isoprenylcysteine O-methyltransferase activity|S-farnesylcysteine methyltransferase activity|protein S-farnesylcysteine C-terminal methyltransferase activity|prenylcysteine carboxylmethyltransferase activity|protein C-terminal farnesylcysteine O-methyltransferase activity|isoprenylcysteine carboxylmethyltransferase activity|farnesyl cysteine C-terminal methyltransferase activity|prenylcysteine carboxymethyltransferase activity|prenylcysteine methyltransferase activity|farnesyl-protein carboxymethyltransferase activity|prenylated protein methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + protein C-terminal S-farnesyl-L-cysteine = S-adenosyl-L-homocysteine + protein C-terminal S-farnesyl-L-cysteine methyl ester. CHEBI:43577 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_43577 GO:0004673 protein histidine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004673 EC:2.7.13.3|MetaCyc:2.7.13.3-RXN HP165|histidine kinase (ambiguous)|histidine protein kinase (ambiguous)|protein histidine kinase (ambiguous)|Sln1p|ATP:protein-L-histidine N-phosphotransferase activity|histidine kinase activity|EnvZ|protein kinase (histidine) (ambiguous)|histidine protein kinase activity|protein-histidine kinase activity|protein kinase (histidine)|HK1 Catalysis of the reaction: ATP + protein L-histidine = ADP + protein phospho-L-histidine. GO:0004672 protein kinase activity biolink:MolecularActivity go-plus goslim_candida|goslim_aspergillus http://purl.obolibrary.org/obo/GO_0004672 Reactome:R-HSA-9673284|Reactome:R-HSA-9604606|MetaCyc:PROTEIN-KINASE-RXN|Reactome:R-HSA-975139|Reactome:R-HSA-156832|Reactome:R-HSA-937034 protamine kinase activity Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP. CHEBI:43572 kojic acid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_43572 CHEBI:137965 4-methoxyestrone 3-O-(beta-D-glucuronide) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137965 PR:000005932 granulocyte colony-stimulating factor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000005932 G-CSF|pluripoietin|Csfg|GCSF|lenograstim|CSF3|filgrastim A protein that is a translation product of the human CSF3 gene or a 1:1 ortholog thereof. PR:000005931 granulocyte-macrophage colony-stimulating factor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000005931 GM-CSF|colony-stimulating factor|GMCSF|CSF2|sargramostim|Csfgm|CSF|molgramostin A protein that is a translation product of the human CSF2 gene or a 1:1 ortholog thereof. CHEBI:137967 N(6)-acyl-L-lysine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137967 CHEBI:137966 4-methoxy-17beta-estradiol 3-O-(beta-D-glucuronide) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137966 CHEBI:137961 4-hydroxyestrone 4-O-(beta-D-glucuronide) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137961 CHEBI:137960 4-hydroxyestrone 3-O-(beta-D-glucuronide) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137960 CHEBI:28726 3-oxotetradecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28726 CHEBI:28725 N(6')-acetylkanamycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28725 CHEBI:28728 thromboxane B2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28728 CHEBI:28727 trans-vaccenic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28727 CHEBI:28721 ribulose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28721 CHEBI:28724 9,10-dihydroxyoctadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28724 CHEBI:28723 D-glycero-D-manno-heptose 7-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28723 CHEBI:7508 framycetin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_7508 CHEBI:7507 neomycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_7507 CHEBI:28729 alpha-D-mannose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28729 CHEBI:28733 1-linoleoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28733 CHEBI:28731 gibberellin A19 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28731 CHEBI:7510 neopinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_7510 CHEBI:28706 trans-hex-2-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28706 CHEBI:28700 20-hydroxy-leukotriene E4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28700 CHEBI:28701 chenodeoxycholoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28701 GO:0038195 urokinase plasminogen activator signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038195 uPA signaling pathway A series of molecular signals initiated by the binding of urokinase plasminogen activator to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0038194 thyroid-stimulating hormone signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038194 TSH signaling pathway|thyrotropin signaling pathway The series of molecular signals generated as a consequence of thyroid-stimulating hormone (thyrotropin) binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription. GO:0038197 type I interferon receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0038197 interferon-alpha/beta receptor complex A heterodimeric protein complex that binds a type I interferon and transmits the signal across the membrane into the cell. Consists of an alpha subunit (IFNAR1) and a beta subunit (IFNAR2). GO:0038196 type III interferon signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038196 type III interferon-activated signaling pathway|interferon lambda signaling pathway A series of molecular signals initiated by the binding of a type III interferon to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Interferon lambda is the only member of the type III interferon found so far. GO:0038199 ethylene receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038199 ethylene response sensor|C2H4 receptor activity Combining with ethylene and transmitting the signal in the cell to initiate a change in cell activity. GO:0038198 auxin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038198 Combining with auxin and transmitting the signal in the cell to initiate a change in cell activity. Auxin is a plant hormone (phytohormone). CHEBI:28715 5-hydroxykynurenamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28715 CHEBI:28717 O-decanoyl-L-carnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28717 CHEBI:28716 palmitoleic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28716 GO:0038191 neuropilin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038191 neuropilin-binding|Nrp binding|Nrp ligand Interacting selectively and non-covalently with a member of the neuropilin family. GO:0038190 VEGF-activated neuropilin signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038190 VEGF-Npn-1 signaling|vascular endothelial growth factor-activated neuropilin signaling pathway A series of molecular signals initiated by the binding of vascular endothelial growth factor (VEGF) to a neuropilin protein on the surface of a target cell, followed by transmission of the signal, and ending with regulation of a downstream cellular process, e.g. transcription. CHEBI:28710 3-hydroxy-3-methyl-2-oxopentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28710 GO:0038193 thromboxane A2 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038193 TXA(2) receptor signaling|TXA2 signaling The series of molecular signals generated as a consequence of thromboxane A2 binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription. GO:0038192 gastric inhibitory peptide signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038192 GIP signaling|glucose-dependent insulinotropic polypeptide signaling|gastric inhibitory polypeptide receptor signaling pathway The series of molecular signals generated as a consequence of a gastric inhibitory peptide (GIP) binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription. GO:0038184 cell surface bile acid receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038184 membrane bile acid receptor signaling pathway A series of molecular signals initiated by binding of a bile acid to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0038183 bile acid signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038183 A series of molecular signals initiated by the binding of a bile acid to a receptor, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0038186 lithocholic acid receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038186 LCA receptor activity Combining with lithocholic acid and transmitting the signal to initiate a change in cell activity. GO:0038185 intracellular bile acid receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038185 nuclear bile acid receptor signaling pathway A series of molecular signals initiated by a bile acid binding to an receptor located within a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0038188 cholecystokinin signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038188 CCK signaling|cholecystokinin receptor signaling pathway The series of molecular signals generated as a consequence of cholecystokinin binding to a receptor on the surface of the cell, and proceeding with the activated receptor transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity. Ends with regulation of a downstream cellular process, e.g. transcription. CHEBI:28719 4-hydroxyphenylglyoxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28719 GO:0038187 pattern recognition receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038187 PRR activity|pathogen associated molecular pattern receptor activity|MAMP receptor activity|PRR|signaling pattern recognition receptor activity|PAMP receptor activity|macrophage receptor activity|microbe-associated molecular pattern receptor activity Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species to initiate an innate immune response. CHEBI:28718 L-allothreonine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28718 GO:0038189 neuropilin signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038189 Npn signaling A series of molecular signals initiated by the binding of an extracellular ligand to a neuropilin protein on the surface of a target cell, followed by transmission of the signal, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0038180 nerve growth factor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038180 NGF signaling pathway|nerve growth factor signalling pathway A series of molecular signals initiated by the binding of nerve growth factor (NGF) to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0038182 G protein-coupled bile acid receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038182 Wikipedia:G_protein-coupled_bile_acid_receptor cell surface bile acid receptor|G-protein coupled bile acid receptor activity|membrane bile acid receptor activity Combining with an extracellular bile acid and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. GO:0038181 bile acid receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038181 Combining with a bile acid and transmitting the signal to initiate a change in cell activity. A bile acid is any member of a group of steroid carboxylic acids occurring in bile. GO:0038173 interleukin-17A-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038173 IL17A signaling pathway|IL-17A-mediated signaling pathway|interleukin-17A-mediated signalling pathway|interleukin-17A signaling pathway|IL17a signaling pathway A series of molecular signals initiated by the binding of interleukin-17A to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0038172 interleukin-33-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038172 IL-33-mediated signaling pathway|IL33 signaling pathway|interleukin-33-mediated signalling pathway|interleukin-33 signaling pathway A series of molecular signals initiated by the binding of interleukin-33 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. CHEBI:7540 neurosporaxanthin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_7540 GO:0038175 negative regulation of SREBP signaling pathway in response to increased oxygen levels biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038175 negative regulation of SREBP-mediated signaling pathway in response to increased oxygen levels|negative regulation of SREBP-mediated signaling pathway in presence of oxygen Any process that stops, prevents or reduces the frequency, rate or extent of the SREBP signaling pathway in response to an increase in oxygen levels. GO:0038174 interleukin-17A receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038174 Combining with the cytokine interleukin-17A and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0038177 death receptor agonist activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038177 death receptor activator activity Interacting with a death receptor such that the proportion of death receptors in an active form is increased. Ligand binding to a death receptor often induces a conformational change to activate the receptor. GO:0038176 positive regulation of SREBP signaling pathway in response to decreased oxygen levels biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038176 positive regulation of SREBP-mediated signaling pathway in absence of oxygen|positive regulation of SREBP-mediated signaling pathway in response to decreased oxygen levels Any process that activates or increases the frequency, rate or extent of the SREBP signaling pathway in response to a decrease in oxygen levels. GO:0038179 neurotrophin signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038179 neurotrophin receptor signaling pathway A series of molecular signals initiated by the binding of a neurotrophin to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Neurotrophins are a family of secreted growth factors that induce the survival, development, and function of neurons. GO:0038178 complement component C5a signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038178 complement component C5a-induced signaling pathway A series of molecular signals generated as a consequence of a the C5a component of the complement pathway binding to a complement receptor, and ending with regulation of a downstream cellular process. C5a is a peptide derived from the C5 complement factor. CHEBI:77703 EC 4.3.1.3 (histidine ammonia-lyase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77703 CHEBI:77706 EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77706 GO:0038171 cannabinoid signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038171 cannabinoid receptor signaling pathway|cannabinoid-mediated signaling pathway|cannabinoid-activated signaling pathway The series of molecular signals generated as a consequence of a cannabinoid binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription. Cannabinoids are a class of diverse chemical compounds that include the endocannabinoids and the phytocannabinoids. GO:0038170 somatostatin signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038170 somatostatin-activated somatostatin receptor signaling pathway|somatostatin signalling pathway|somatotrophin release inhibiting factor signaling pathway|somatostatin-mediated signaling pathway|SST signaling pathway|SRIF signaling pathway The series of molecular signals generated as a consequence of the peptide somatostatin (SST) binding to a somatostatin receptor (SSTR). The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription. CHEBI:77705 EC 3.4.19.* (omega-peptidase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77705 CHEBI:77709 alpha-N-acetylneuraminosyl-(2->3)-[beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')--N-acylsphingosine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77709 GO:0038169 somatostatin receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038169 SST receptor signaling pathway|SSTR signaling pathway The series of molecular signals generated as a consequence of a somatostatin receptor (SSTR) binding to one of its physiological ligands and transmitting the signal to a heterotrimeric G-protein complex. The pathway ends with regulation of a downstream cellular process, e.g. transcription. GO:0038162 erythropoietin-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038162 erythropoietin receptor signaling pathway|EPO-R signaling pathway A series of molecular signals initiated by the binding of erythropoietin (EPO) to the erythropoietin receptor (EPO-R) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0038161 prolactin signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038161 prolactin-mediated signaling pathway|PRL signaling pathway A series of molecular signals initiated by the binding of the peptide hormone prolactin to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0038164 thrombopoietin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038164 Combining with the glycoprotein thrombopoietin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0038163 thrombopoietin-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038163 thrombopoietin receptor signaling pathway|THPO signaling pathway|THPO/MPL signaling pathway A series of molecular signals initiated by the binding of a thrombopoietin to the thrombopoietin receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. CHEBI:77700 methyl acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77700 GO:0038166 angiotensin-activated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038166 angiotensin-mediated signaling pathway|angiotensin receptor signaling pathway|angiotensin II-mediated signaling pathway The series of molecular signals generated as a consequence of angiotensin II binding to an angiotensin receptor on the surface of the cell, and proceeding with the activated receptor transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity. Ends with regulation of a downstream cellular process, e.g. transcription. GO:0038165 oncostatin-M-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038165 oncostatin-M signaling pathway|OSM signaling pathway A series of molecular signals initiated by the binding of oncostatin-M (OSM) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. OSM can signal via at least two different receptors (a specific receptor and a LIF receptor) to activate different downstream signal transduction pathways. GO:0038168 epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038168 EGFR signaling pathway via IKK-dependent activation of NF-kappaB|EGFR signaling pathway via IKK/NF-kappaB cascade The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to one of its physiological ligands, where the signal is passed on within the cell via I-kappaB-kinase (IKK)-dependent activation of the transcription factor NF-kappaB. GO:0038167 epidermal growth factor receptor signaling pathway via positive regulation of NF-kappaB transcription factor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038167 epidermal growth factor receptor signalling pathway via positive regulation of NF-kappaB transcription factor activity|EGFR signaling pathway via activation of NF-kappaB The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to one of its physiological ligands, where the signal is passed on within the cell via activation of the transcription factor NF-kappaB. CHEBI:77715 nasal decongestant biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77715 CHEBI:77712 xanthoaphin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77712 CHEBI:77718 carboxamidinium ion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77718 GO:0038160 CXCL12-activated CXCR4 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038160 CXCL12-activated CXCR4 signalling pathway A series of molecular signals initiated by the binding of the C-X-C chemokine CXCL12 to a C-X-C chemokine type 4 receptor (CXCR4) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. CHEBI:77717 2,2'-lysobisphosphatidate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77717 GO:0038159 C-X-C chemokine receptor CXCR4 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038159 CXCR4 signaling pathway A series of molecular signals initiated by a the C-X-C chemokine type 4 receptor on the surface of a cell binding to one of it's physiological ligands, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0038158 granulocyte colony-stimulating factor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038158 CSF3 signaling pathway|G-CSF receptor signaling pathway|G-CSF signaling pathway|granulocyte colony-stimulating factor receptor signaling pathway|granulocyte colony-stimulating factor signalling pathway A series of molecular signals initiated by the binding of the cytokine granulocyte colony-stimulating factor (G-CSF) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. G-CSF binds to the receptor (CSF3R). CHEBI:7524 nerolidol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_7524 GO:0038151 CCL2-activated CCR2 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038151 CCL2/CCR2 signaling pathway A series of molecular signals initiated by the binding of the C-C chemokine CCL2 to a C-C chemokine type 2 receptor (CCR2) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0038150 C-C chemokine receptor CCR2 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038150 C-C chemokine receptor type 2 signaling pathway A series of molecular signals initiated by a the C-C chemokine type 2 receptor (CCR2) on the surface of a cell binding to one of it's physiological ligands, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0038153 CCL2-activated CCR4 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038153 CCL2/CCR4 signaling pathway A series of molecular signals initiated by the binding of the C-C chemokine CCL2 to a C-C chemokine type 4 receptor (CCR4) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0038152 C-C chemokine receptor CCR4 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038152 chemokine receptor CCR4 signaling pathway|C-C chemokine receptor type 4 signaling pathway A series of molecular signals initiated by a the C-C chemokine type 2 receptor (CCR4) on the surface of a cell binding to one of it's physiological ligands, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0038155 interleukin-23-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038155 interleukin-23-mediated signalling pathway|IL-23-mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-23 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. CHEBI:77711 licodione(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77711 GO:0038154 interleukin-11-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038154 interleukin-11-mediated signalling pathway|IL-11-mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-11 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. CHEBI:77710 3',4',5-trihydroxy-3,7-dimethoxyflavone(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77710 GO:0038157 granulocyte-macrophage colony-stimulating factor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038157 CSF2 signaling pathway|GM-CSF receptor signaling pathway|granulocyte-macrophage colony-stimulating factor receptor signaling pathway|GM-CSF signaling pathway|granulocyte-macrophage colony-stimulating factor signalling pathway A series of molecular signals initiated by the binding of the cytokine granulocyte macrophage colony-stimulating factor (GM-CSF) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GM-CSF binds to a heterodimer receptor (CSF2R) consisting of an alpha ligand-binding subunit, and a common beta subunit that is shared with other cytokine receptors. GO:0038156 interleukin-3-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038156 interleukin-3-mediated signalling pathway|IL-3-mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-3 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. CHEBI:77726 1-decanoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77726 CHEBI:77725 17-O-acetylnorajmaline(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77725 CHEBI:77724 1-decanoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77724 CHEBI:77728 bergaptol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77728 CHEBI:77727 delta-lactam biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77727 GO:0038148 chemokine (C-C motif) ligand 2 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038148 CCL2 signaling pathway A series of molecular signals initiated by the binding of the C-C chemokine CCL2 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0038147 C-X-C motif chemokine 12 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038147 CXCR7|CXCR4|stromal cell-derived factor-1 receptor activity|CXCL12 receptor activity|SDF-1 receptor activity Combining with the C-X-C motif chemokine 12 (CXCL12) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0038149 C-C motif chemokine 2 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038149 CCL2 receptor activity Combining with the C-C motif chemokine 2 (CCL2) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. CHEBI:7539 5-amino-3,5-dideoxy-D-glycero-D-galacto-non-2-ulopyranosonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_7539 GO:0038140 ERBB4-ERBB3 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0038140 ERBB3-ERBB4 complex|ERBB4:ERBB3 heterodimer A heterodimeric complex between the tyrosine kinase receptors ERBB4 (also called HER4) and ERBB3 (also called HER3). ERBB3 has impaired kinase activity so relies on the kinase activity of its heterodimer partner for activation and signal transmission. GO:0038142 EGFR:ERBB2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0038142 EGFR:ERBB2 heterodimer|EGF:EGFR:ERBB2 complex A heterodimeric complex between the tyrosine kinase receptor ERBB2 and a ligand-activated epidermal growth factor receptor (EGFR/ERBB1). ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as EGFR. GO:0038141 ERBB4-ERBB4 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0038141 ERBB4 homodimer A homodimeric complex containing two monomers of the tyrosine kinase receptor ERBB4 (also called HER4). GO:0038144 ERBB4:ERBB2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0038144 NRGs/EGFLs:ERBB4:ERBB2|ERBB4:ERBB2 heterodimer A heterodimeric complex between the tyrosine kinase receptor ERBB2 and a ligand-activated receptor ERBB4. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB4. CHEBI:77722 apigenin 7-O-beta-D-glucoside(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77722 GO:0038143 ERBB3:ERBB2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0038143 EGFR:ERBB2 heterodimer|NRG1/2:ERBB3:ERBB2 A heterodimeric complex between the tyrosine kinase receptor ERBB2 and a ligand-activated receptor ERBB3. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB3. GO:0038146 chemokine (C-X-C motif) ligand 12 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038146 SDF1 signaling pathway|stromal cell-derived factor-1 signaling pathway|CXCL12 signaling pathway|CXCL12-activated CXCR7 signaling pathway A series of molecular signals initiated by the binding of the chemokine CXCL12 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. CHEBI:77720 1,1'-lysobisphosphatidate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77720 GO:0038145 macrophage colony-stimulating factor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038145 M-CSF signaling pathway|macrophage colony-stimulating factor signalling pathway A series of molecular signals initiated by the binding of the cytokine macrophage colony-stimulating factor (M-CSF) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0004800 thyroxine 5'-deiodinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004800 MetaCyc:THYROXINE-DEIODINASE-RXN|EC:1.21.99.4|Reactome:R-HSA-209772|Reactome:R-HSA-350869|RHEA:19745 type II iodothyronine deiodinase activity|outer ring-deiodinating pathway|type I iodothyronine deiodinase activity|iodothyronine outer ring monodeiodinase activity|thyroxine deiodinase activity|acceptor:3,5,3'-triiodo-L-thyronine oxidoreductase (iodinating)|diiodothyronine 5'-deiodinase activity|iodothyronine 5'-deiodinase activity|L-thyroxine iodohydrolase (reducing) activity|thyroxine 5' deiodinase activity Catalysis of the reaction: 3,5,3'-L-triiodo-L-thyronine + iodide + acceptor + H+ = L-thyroxine + donor-H2. GO:0004802 transketolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004802 EC:2.2.1.1|Reactome:R-HSA-163741|Reactome:R-HSA-163751|MetaCyc:1TRANSKETO-RXN|Reactome:R-HSA-71324|RHEA:10508|Reactome:R-HSA-71335 glycolaldehydetransferase activity|sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glycolaldehydetransferase activity|glycoaldehyde transferase activity|fructose 6-phosphate:D-glyceraldehyde-3-phosphate glycolaldehydetransferase activity Catalysis of the reversible transfer of a 2-carbon ketol group (CH2OH-CO-) from a ketose phosphate donor to an aldose phosphate acceptor. GO:0004801 sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004801 EC:2.2.1.2|RHEA:17053|Reactome:R-HSA-163764|MetaCyc:TRANSALDOL-RXN|Reactome:R-HSA-5659989|Reactome:R-HSA-71334|Reactome:R-HSA-5659998 dihydroxyacetone transferase activity|glycerone transferase activity|dihydroxyacetonetransferase activity|transaldolase activity Catalysis of the reaction: sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate. UBERON:0035956 epididymal lumen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035956 lumen of epididymis|epididymis lumen The lumen of the epididymis CHEBI:14158 dihydromonacolin L biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_14158 GO:0004808 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004808 RHEA:19569|MetaCyc:2.1.1.61-RXN|KEGG_REACTION:R00601|EC:2.1.1.61 S-adenosyl-L-methionine:tRNA (5-methylaminomethyl-2-thio-uridylate)-methyltransferase activity|tRNA 5-methylaminomethyl-2-thiouridylate 5'-methyltransferase activity|transfer ribonucleate 5-methylaminomethyl-2-thiouridylate 5-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA containing 5-aminomethyl-2-thiouridine = S-adenosyl-L-homocysteine + tRNA containing 5-methylaminomethyl-2-thiouridylate. GO:0004807 triose-phosphate isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004807 EC:5.3.1.1|RHEA:18585|MetaCyc:TRIOSEPISOMERIZATION-RXN|Reactome:R-HSA-70454|Reactome:R-HSA-70481|KEGG_REACTION:R01015 phosphotriose isomerase activity|triose phosphate mutase activity|D-glyceraldehyde-3-phosphate aldose-ketose-isomerase activity|triosephosphate mutase activity|D-glyceraldehyde-3-phosphate ketol-isomerase activity|triosephosphate isomerase activity|triose phosphoisomerase activity Catalysis of the reaction: D-glyceraldehyde 3-phosphate = glycerone phosphate. CHEBI:38120 but-3-en-4-olide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38120 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004809 Reactome:R-HSA-6782416|Reactome:R-HSA-6786501 tRNA 2,2-dimethylguanosine-26 methyltransferase activity|S-adenosyl-L-methionine:tRNA (guanine-N2-)-methyltransferase activity|tRNA(m(2,2)G26)dimethyltransferase activity|transfer RNA guanine 2-methyltransferase activity|transfer ribonucleate guanine N2-methyltransferase activity|S-adenosyl-L-methionine:tRNA (guanine-2-N-)-methyltransferase activity|transfer ribonucleate guanine 2-methyltransferase activity|tRNA(guanine-26,N2-N2) methyltransferase activity|tRNA(guanine-26,N(2)-N(2)) methyltransferase activity|guanine-N2-methylase activity|N2,N2-dimethylguanine tRNA methyltransferase activity|N(2),N(2)-dimethylguanine tRNA methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA containing guanine = S-adenosyl-L-homocysteine + tRNA containing N2-methylguanine. GO:0004804 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004804 CHEBI:38124 dialdehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38124 GO:0004803 transposase activity biolink:MolecularActivity go-plus goslim_pir|goslim_metagenomics http://purl.obolibrary.org/obo/GO_0004803 P-element encoded transposase activity Catalysis of the transposition of transposable elements or transposons. Transposases are involved in recombination required for transposition and are site-specific for the transposon/transposable element. GO:0004806 triglyceride lipase activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0004806 RHEA:12044|Reactome:R-HSA-8848339|Reactome:R-HSA-8848338|EC:3.1.1.3|MetaCyc:TRIACYLGLYCEROL-LIPASE-RXN|Reactome:R-HSA-1482777|Reactome:R-HSA-5694109|Reactome:R-HSA-163551 meito MY 30|triacetinase activity|heparin releasable hepatic lipase|butyrinase activity|meito sangyo OF lipase|amano AP|glycerol-ester hydrolase activity|amano B|cacordase activity|triolein hydrolase activity|triglyceride hydrolase activity|triacylglycerol acylhydrolase activity|salt-resistant post-heparin lipase|tween-hydrolyzing esterase activity|TAG activity|lipazin|tributyrinase activity|hepatic monoacylglycerol acyltransferase|tween hydrolase activity|takedo 1969-4-9|PPL|amano CE|glycerol ester hydrolase activity|triacylglycerol ester hydrolase activity|tributyrase activity|GEH|hepatic lipase|triacylglycerol lipase activity|post-heparin plasma protamine-resistant lipase|tweenase activity|GA 56|amano CES|amano P|steapsin|liver lipase|tweenesterase activity|tributyrin esterase activity|capalase L|amno N-AP|triglyceridase activity Catalysis of the reaction: triacylglycerol + H2O = diacylglycerol + a carboxylate. CHEBI:7587 nitroalkane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_7587 GO:0004805 trehalose-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004805 MetaCyc:TREHALOSEPHOSPHA-RXN|EC:3.1.3.12|RHEA:23420 trehalose 6-phosphate phosphatase activity|trehalose 6-phosphatase activity|trehalose-6-phosphate phosphohydrolase activity|trehalose phosphatase activity Catalysis of the reaction: trehalose 6-phosphate + H2O = trehalose + phosphate. CHEBI:38122 2-chloro-4-carboxymethylenebut-2-en-1,4-olide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38122 CHEBI:87091 8-amino-3,8-dideoxy-alpha-D-manno-oct-2-ulosonic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87091 GO:0004811 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004811 GO:0004810 tRNA adenylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004810 MetaCyc:TRNA-ADENYLYLTRANSFERASE-RXN|EC:2.7.7.72 transfer ribonucleic adenylyl (cytidylyl) transferase|tRNA-nucleotidyltransferase activity|transfer ribonucleate cytidylyltransferase|transfer ribonucleic-terminal trinucleotide nucleotidyltransferase|ATP:tRNA adenylyltransferase activity|tRNA CCA-pyrophosphorylase activity|tRNA CCA-diphosphorylase activity|transfer ribonucleate adenylyltransferase|transfer ribonucleate nucleotidyltransferase|CCA-adding enzyme activity|CTP(ATP):tRNA nucleotidyltransferase|transfer RNA adenylyltransferase|ribonucleic cytidylic cytidylic adenylic pyrophosphorylase|ATP (CTP):tRNA nucleotidyltransferase|-C-C-A pyrophosphorylase|transfer ribonucleate adenyltransferase activity|ribonucleic cytidylyltransferase|transfer-RNA nucleotidyltransferase|tRNA adenylyl(cytidylyl)transferase|ATP(CTP)-tRNA nucleotidyltransferase|transfer ribonucleic acid nucleotidyl transferase Catalysis of the reaction: ATP + tRNA(n) = diphosphate + tRNA(n+1). CHEBI:87090 (7R)-6-deoxy-D-manno-oct-7-ulosuronate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87090 GO:0004813 alanine-tRNA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004813 Reactome:R-HSA-379864|MetaCyc:ALANINE--TRNA-LIGASE-RXN|EC:6.1.1.7|RHEA:12540|Reactome:R-HSA-380177 alanine tRNA synthetase activity|alanine transfer RNA synthetase activity|Ala-tRNA synthetase activity|alanyl-transfer ribonucleate synthase activity|alanyl-transfer ribonucleic acid synthetase activity|alanyl-transfer ribonucleate synthetase activity|alanine-transfer RNA ligase activity|alanyl-transfer RNA synthetase activity|alanine translase activity|AlaRS|alanyl-tRNA synthetase activity|L-alanine:tRNAAla ligase (AMP-forming) Catalysis of the reaction: ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala). GO:0004812 aminoacyl-tRNA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004812 EC:6.1.1.- ligase activity, forming aminoacyl-tRNA and related compounds|aminoacyl-tRNA synthetase auxiliary protein activity|aminoacyl-tRNA synthetase activity Catalysis of the formation of aminoacyl-tRNA from ATP, amino acid, and tRNA with the release of diphosphate and AMP. CHEBI:87095 lipid A 1-(2-aminoethyl diphosphate)(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87095 CHEBI:87097 lipid A 4'-(2-aminoethyl diphosphate)(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87097 CHEBI:53756 HIV-1 reverse transcriptase inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53756 CHEBI:87096 lipid A 1,4'-bis(2-aminoethyl diphosphate)(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87096 UBERON:0011980 crurotarsal joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011980 crurotarsal A joint that connects the bones of the crus to the proximal tarsal bones UBERON:0011977 epiphysis of proximal phalanx of manus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011977 epiphysis of proximal phalanx of finger An epiphysis that is part of a proximal phalanx of manus. UBERON:0011976 epiphysis of distal phalanx of pes biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011976 epiphysis of distal phalanx of toe An epiphysis that is part of a distal phalanx of pes. UBERON:0035965 wall of blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035965 blood vessel wall|vascular wall CHEBI:38139 (1S,2R)-1,2-dihydronaphthalene-1,2-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38139 UBERON:0011975 epiphysis of middle phalanx of pes biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011975 epiphysis of middle phalanx of toe An epiphysis that is part of a middle phalanx of pes. UBERON:0011974 epiphysis of proximal phalanx of pes biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011974 epiphysis of proximal phalanx of toe An epiphysis that is part of a proximal phalanx of pes. UBERON:0011979 epiphysis of distal phalanx of manus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011979 epiphysis of distal phalanx of finger An epiphysis that is part of a distal phalanx of manus. CHEBI:14148 dihydrodipicolinate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_14148 UBERON:0011978 epiphysis of middle phalanx of manus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011978 epiphysis of middle phalanx of finger An epiphysis that is part of a middle phalanx of manus. GO:0004819 glutamine-tRNA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004819 EC:6.1.1.18|RHEA:20121|MetaCyc:GLUTAMINE--TRNA-LIGASE-RXN|Reactome:R-HSA-379982|Reactome:R-HSA-380241 glutaminyl-transfer RNA synthetase activity|L-glutamine:tRNAGln ligase (AMP-forming)|glutaminyl-transfer ribonucleate synthetase activity|glutamine-tRNA synthetase activity|glutamine translase activity|glutaminyl ribonucleic acid|GlnRS|glutaminyl-tRNA synthetase activity Catalysis of the reaction: ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln). CHEBI:38132 indanone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38132 GO:0004818 glutamate-tRNA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004818 EC:6.1.1.17|Reactome:R-HSA-379861|RHEA:23540|Reactome:R-HSA-380216|MetaCyc:GLURS-RXN glutamyl-transfer ribonucleate synthetase activity|L-glutamate:tRNAGlu ligase (AMP-forming) activity|glutamic acid translase activity|glutamyl-tRNA synthetase activity|glutamyl-transfer ribonucleic acid synthetase activity|glutamate-tRNA synthetase activity|glutamyl-transfer RNA synthetase activity Catalysis of the reaction: ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu). CHEBI:38131 lactol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38131 CHEBI:53753 triolein biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_53753 GO:0004815 aspartate-tRNA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004815 Reactome:R-HSA-379867|EC:6.1.1.12|RHEA:19649|MetaCyc:ASPARTATE--TRNA-LIGASE-RXN|Reactome:R-HSA-380229 aspartyl ribonucleate synthetase activity|aspartyl-tRNA synthetase activity|aspartyl-transfer RNA synthetase activity|aspartyl ribonucleic synthetase activity|L-aspartate:tRNAAsp ligase (AMP-forming)|aspartic acid translase activity|aspartyl-transfer ribonucleic acid synthetase activity Catalysis of the reaction: ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp). GO:0004814 arginine-tRNA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004814 RHEA:20301|Reactome:R-HSA-379993|MetaCyc:ARGININE--TRNA-LIGASE-RXN|Reactome:R-HSA-380224|EC:6.1.1.19 arginyl-transfer ribonucleate synthetase activity|arginyl transfer ribonucleic acid synthetase activity|arginine translase activity|arginyl-transfer RNA synthetase activity|L-arginine:tRNAArg ligase (AMP-forming)|arginyl-tRNA synthetase activity|arginine-tRNA synthetase activity Catalysis of the reaction: ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). GO:0004817 cysteine-tRNA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004817 Reactome:R-HSA-379887|EC:6.1.1.16|RHEA:17773|MetaCyc:CYSTEINE--TRNA-LIGASE-RXN|Reactome:R-HSA-380158 cysteinyl-transferRNA synthetase activity|cysteinyl-transfer ribonucleate synthetase activity|cysteine translase activity|cysteinyl-tRNA synthetase activity|L-cysteine:tRNACys ligase (AMP-forming) Catalysis of the reaction: ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys). GO:0004816 asparagine-tRNA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004816 KEGG_REACTION:R03648|EC:6.1.1.22|Reactome:R-HSA-379996|MetaCyc:ASPARAGINE--TRNA-LIGASE-RXN|RHEA:11180|Reactome:R-HSA-380227 asparagine translase activity|asparaginyl transfer RNA synthetase activity|L-asparagine:tRNAAsn ligase (AMP-forming)|asparaginyl-transfer ribonucleate synthetase activity|asparagyl-transfer RNA synthetase activity|asparaginyl transfer ribonucleic acid synthetase activity|asparaginyl-tRNA synthetase activity Catalysis of the reaction: L-asparagine + ATP + tRNA(Asn) = AMP + Asn-tRNA(Asn) + diphosphate + 2 H(+). CHEBI:38133 naphthalenediol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38133 CHEBI:7570 nigerose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_7570 CHEBI:28788 quinoline-3,4-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28788 CHEBI:28787 nitroglycerin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28787 CHEBI:53746 EC 1.1.1.205 (IMP dehydrogenase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53746 CHEBI:28789 L-glucitol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28789 CHEBI:28785 (+)-ureidoglycolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28785 UBERON:0011973 epiphysis of phalanx of pes biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011973 epiphysis of phalanx of toe An epiphysis that is part of a phalanx of a pes [Automatically generated definition]. UBERON:0011972 medial ligament of ankle joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011972 ligamentum collaterale mediale articulationis talocruralis|deltoid collateral ligament of ankle joint|medial collateral ligament of ankle joint|ligamentum deltoideum|ligamentum deltoideum (articulatio talocruralis)|ligamentum collaterale mediale (articulatio talocruralis)|deltoid ligament of ankle joint A skeletal ligament that connects a tibia and connects a tarsal skeleton. CHEBI:38107 trans-4-carboxymethylenebut-2-en-4-olide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38107 UBERON:0011965 saddle joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011965 articulation by reciprocal reception|sellar joint In a saddle joint (sellar joint, articulation by reciprocal reception) the opposing surfaces are reciprocally concave-convex. CHEBI:38106 organosulfur heterocyclic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38106 CHEBI:38104 oxacycle biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38104 CHEBI:38109 (R)-azetidine-2-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38109 CHEBI:38108 azetidine-2-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38108 CHEBI:14178 1D-myo-inositol bis(diphosphate) tetrakisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_14178 CHEBI:38102 triazines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38102 CHEBI:38101 organonitrogen heterocyclic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38101 CHEBI:28794 coumarin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28794 CHEBI:28797 D-alpha-aminobutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28797 CHEBI:28796 fructan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28796 CHEBI:28791 isoglutamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28791 CHEBI:28790 serotonin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28790 UBERON:0011960 articular capsule of glenohumeral joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011960 fibrous capsule of glenohumeral joint|articular capsule of humerus|glenohumeral joint capsule|articular capsule of shoulder joint|capsule of shoulder joint An articular capsule that is part of the glenohumeral joint. CHEBI:28793 beta-D-glucan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28793 CHEBI:28792 erucic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28792 CHEBI:38118 but-2-en-4-olide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38118 UBERON:0011955 left hepatic vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011955 A hepatic vein that is part of a left lobe of liver. UBERON:0011953 stomach glandular region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011953 glandular stomach A region of the stomach that is lined with glandular epithelium. UBERON:0011956 right hepatic vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011956 A hepatic vein that is part of a right lobe of liver. CHEBI:38113 (R,R,R)-nicotianamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38113 CHEBI:38111 benzoindole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38111 CHEBI:28766 uroporphyrinogen I biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28766 CHEBI:28765 phosphatidylinositol phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28765 CHEBI:28768 p-cymene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28768 CHEBI:28767 2-deoxy-D-ribose 1,5-bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28767 CHEBI:28761 N-acetyl-D-galactosaminide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28761 CHEBI:28763 4,4'-dichlorodiphenylmethane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28763 CHEBI:28777 liquiritigenin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28777 CHEBI:28775 hesperidin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28775 CHEBI:28774 3,3',5'-triiodothyronine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28774 CHEBI:28770 norlaudanosoline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28770 CHEBI:14105 deamido-NAD zwitterion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_14105 UBERON:0035927 sulcus of parietal lobe biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035927 parietal lobe sulci|parietal lobe sulcus|PLs CHEBI:28748 doxorubicin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28748 CHEBI:28747 picolinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28747 CHEBI:28749 aryl beta-D-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28749 CHEBI:28744 2-hydroxy-17beta-estradiol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28744 CHEBI:28743 alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1->1')-Cer biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28743 CHEBI:28745 L-xylo-hex-3-ulonolactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28745 CHEBI:28759 3-oxo-3-phenylpropionic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28759 CHEBI:28755 2,4,6-trichlorophenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28755 CHEBI:28757 fructose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28757 CHEBI:28751 biochanin A 7-O-beta-D-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28751 CHEBI:28750 17alpha-hydroxypregnenolone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28750 UBERON:0011997 coelom biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011997 schizocoelom|coelem|enterocoelom|coelomic cavity|haemocoelom The aggregate of the coelemic cavity lumen plus the membranes that line the lumen. GO:0004767 sphingomyelin phosphodiesterase activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0004767 RHEA:19253|Reactome:R-HSA-1640164|Reactome:R-HSA-193706|Reactome:R-HSA-1605797|EC:3.1.4.12|Reactome:R-HSA-1606288|MetaCyc:SPHINGOMYELIN-PHOSPHODIESTERASE-RXN|Reactome:R-HSA-1606273|KEGG_REACTION:R02541 sphingomyelin cholinephosphohydrolase activity|sphingomyelinase activity Catalysis of the reaction: H(2)O + sphingomyelin = ceramide + choline phosphate + H(+). CHEBI:38091 spirostanyl glycoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38091 GO:0004766 spermidine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004766 EC:2.5.1.16|MetaCyc:SPERMIDINESYN-RXN|RHEA:12721|Reactome:R-HSA-351215 spermidine synthetase activity|putrescine aminopropyltransferase activity|SpeE|aminopropyltransferase activity|S-adenosylmethioninamine:putrescine 3-aminopropyltransferase activity Catalysis of the reaction: S-adenosylmethioninamine + putrescine = 5'-methylthioadenosine + spermidine. CHEBI:38090 15beta-hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38090 GO:0004769 steroid delta-isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004769 EC:5.3.3.1|Reactome:R-HSA-193052|MetaCyc:STEROID-DELTA-ISOMERASE-RXN|Reactome:R-HSA-195690|Reactome:R-HSA-193961|RHEA:14709|Reactome:R-HSA-193073|Reactome:R-HSA-6807052 3-oxosteroid delta5-delta4-isomerase activity|3-oxosteroid isomerase activity|delta(5)-steroid isomerase activity|delta(5)-3-keto steroid isomerase activity|delta5-ketosteroid isomerase activity|delta(5)-3-oxosteroid isomerase activity|steroid D-isomerase activity|delta5-3-keto steroid isomerase activity|steroid isomerase activity|delta5-3-ketosteroid isomerase activity|delta5(or delta4)-3-keto steroid isomerase activity|delta5-3-oxosteroid isomerase activity|delta(5)-3-ketosteroid isomerase activity|hydroxysteroid isomerase activity|delta5-steroid isomerase activity Catalysis of the reaction: a 3-oxo-delta(5)-steroid = a 3-oxo-delta(4)-steroid. GO:0004768 stearoyl-CoA 9-desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004768 RHEA:19721|MetaCyc:1.14.19.1-RXN|EC:1.14.19.1|Reactome:R-HSA-8847579|Reactome:R-HSA-5690565 stearoyl-CoA,ferrocytochrome-b5:oxygen oxidoreductase (9,10-dehydrogenating)|stearoyl-CoA desaturase activity|delta-9 acyl-phospholipid desaturase activity|fatty acid desaturase activity|acyl-CoA desaturase activity|stearoyl-CoA, hydrogen-donor:oxygen oxidoreductase activity|delta9-desaturase activity|delta(9)-desaturase activity Catalysis of the reaction: stearoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ = oleoyl-CoA + 2 ferricytochrome b5 + H2O. GO:0004763 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004763 GO:0004762 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004762 GO:0004765 shikimate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004765 EC:2.7.1.71|MetaCyc:SHIKIMATE-KINASE-RXN|RHEA:13121|KEGG_REACTION:R02412 shikimate kinase (phosphorylating)|shikimate kinase II|ATP:shikimate 3-phosphotransferase activity Catalysis of the reaction: ATP + shikimate = 3-phosphoshikimate + ADP + 2 H(+). CHEBI:38093 phenothiazines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38093 GO:0004764 shikimate 3-dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004764 EC:1.1.1.282|EC:1.1.1.25|KEGG_REACTION:R06847|MetaCyc:SHIKIMATE-5-DEHYDROGENASE-RXN|RHEA:17737 shikimate oxidoreductase activity|shikimate:NADP(+) 5-oxidoreductase activity|dehydroshikimic reductase activity|5-dehydroshikimic reductase activity|DHS reductase activity|shikimate:NADP(+) oxidoreductase activity|5-dehydroshikimate reductase activity Catalysis of the reaction: shikimate + NADP+ = 3-dehydroshikimate + NADPH + H+. GO:0004761 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004761 CHEBI:87024 1-[(6Z,9Z,12Z,15Z)-octadec-6,9,12,15-tetraenoyl]-2-acylglycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87024 GO:0004760 serine-pyruvate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004760 MetaCyc:SERINE--PYRUVATE-AMINOTRANSFERASE-RXN|RHEA:22852|KEGG_REACTION:R00585|EC:2.6.1.51 hydroxypyruvate:L-alanine transaminase activity|SPT|serine-pyruvate aminotransferase activity|serine-pyruvate aminotransferase, type 1|serine-pyruvate aminotransferase, type 2B|serine-pyruvate aminotransferase, type 2A|serine--pyruvate aminotransferase activity|L-serine:pyruvate aminotransferase activity Catalysis of the reaction: L-serine + pyruvate = 3-hydroxypyruvate + L-alanine. CHEBI:87023 1-alpha-linolenoyl 2-acylglycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87023 CHEBI:63056 zinc cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63056 CHEBI:77696 2-hexadecyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77696 CHEBI:77695 1-arachidonyl-2-palmityl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77695 CHEBI:77694 1-arachidonoyl-2-palmitoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77694 CHEBI:77699 methyl formate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77699 CHEBI:38089 15-hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38089 GO:0004778 succinyl-CoA hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004778 KEGG_REACTION:R00407|RHEA:11516|EC:3.1.2.3|MetaCyc:SUCCINYL-COA-HYDROLASE-RXN succinyl coenzyme A hydrolase activity|succinyl coenzyme A deacylase activity|succinyl-CoA acylase activity Catalysis of the reaction: H(2)O + succinyl-CoA = CoA + H(+) + succinate. GO:0004777 succinate-semialdehyde dehydrogenase (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004777 EC:1.2.1.24|RHEA:13217|MetaCyc:SUCCINATE-SEMIALDEHYDE-DEHYDROGENASE-RXN|Reactome:R-HSA-888548 succinate-semialdehyde dehydrogenase activity|succinate semialdehyde dehydrogenase activity|succinate semialdehyde:NAD+ oxidoreductase activity|succinic semialdehyde dehydrogenase activity|succinyl semialdehyde dehydrogenase activity|succinate-semialdehyde:NAD+ oxidoreductase activity Catalysis of the reaction: succinate semialdehyde + NAD+ + H2O = succinate + NADH + H+. GO:0004779 sulfate adenylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004779 sulphate adenylyltransferase activity Catalysis of the transfer of an adenylyl group from an adenosine nucleotide (ATP or ADP) to sulfate, forming adenylylsulfate. GO:0004774 succinate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004774 Catalysis of the reaction: succinate + CoA + nucleotide triphosphate = nucleotide diphosphate + phosphate + succinyl-CoA. CHEBI:63062 aluminium cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63062 GO:0004773 steryl-sulfatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004773 Reactome:R-HSA-1606839|EC:3.1.6.2|MetaCyc:STERYL-SULFATASE-RXN|RHEA:19873 arylsulfatase C activity|steroid 3-sulfatase activity|3-beta-hydroxysteroid sulfate sulfatase activity|dehydroepiandrosterone sulfate sulfatase activity|sterol sulfatase activity|steryl-sulphatase activity|steroid sulfate sulfohydrolase activity|dehydroepiandrosterone sulfatase activity|phenolic steroid sulfatase activity|pregnenolone sulfatase activity|steryl-sulfate sulfohydrolase activity|steroid sulfatase activity Catalysis of the reaction: 3-beta-hydroxyandrost-5-en-17-one 3-sulfate + H2O = 3-beta-hydroxyandrost-5-en-17-one + sulfate. CHEBI:63061 UDP-rhamnose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63061 GO:0004776 succinate-CoA ligase (GDP-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004776 KEGG_REACTION:R00432|MetaCyc:SUCCINATE--COA-LIGASE-GDP-FORMING-RXN|EC:6.2.1.4|RHEA:22120|Reactome:R-HSA-71775 succinyl coenzyme A synthetase|succinyl coenzyme A synthetase (GDP-forming) activity|G-STK|SCS|succinate:CoA ligase (GDP-forming) activity|P-enzyme|succinate-phosphorylating enzyme|succinyl-CoA synthetase (GDP-forming) activity|succinic thiokinase|succinyl CoA synthetase activity|succinyl coenzyme A synthetase (guanosine diphosphate-forming) activity Catalysis of the reaction: GTP + succinate + CoA = GDP + succinyl-CoA + phosphate. GO:0004775 succinate-CoA ligase (ADP-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004775 KEGG_REACTION:R00405|Reactome:R-HSA-70997|EC:6.2.1.5|RHEA:17661|MetaCyc:SUCCCOASYN-RXN succinyl coenzyme A synthetase|succinyl-CoA synthetase activity|A-STK (adenin nucleotide-linked succinate thiokinase)|succinyl coenzyme A synthetase (adenosine diphosphate-forming) activity|succinate thiokinase activity|succinate:CoA ligase (ADP-forming) activity|A-SCS|succinyl-CoA synthetase (ADP-forming) activity|succinic thiokinase Catalysis of the reaction: ATP + succinate + CoA = ADP + succinyl-CoA + phosphate. GO:0004770 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004770 CHEBI:87010 1-linoleoyl-2-acylglycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87010 CHEBI:63065 1,1'-dihydroxy-1,1',2,2'-tetrahydrolycopene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63065 GO:0004772 sterol O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004772 sterol-ester synthetase activity|sterol-ester synthase activity Catalysis of the reaction: acyl-CoA + a sterol = CoA + a sterol ester. GO:0004771 sterol esterase activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0004771 MetaCyc:STEROL-ESTERASE-RXN|RHEA:10100|Reactome:R-HSA-8865667|Reactome:R-HSA-6813720|Reactome:R-HSA-192417|EC:3.1.1.13 sterol ester hydrolase activity|cholesterol ester hydrolase activity|cholesteryl esterase activity|cholesteryl ester synthase activity|triterpenol esterase activity|cholesterase activity|acylcholesterol lipase activity|cholesterol esterase activity|steryl-ester acylhydrolase activity|cholesterol ester synthase activity|cholesteryl ester hydrolase activity Catalysis of the reaction: a steryl ester + H2O = a sterol + a fatty acid. CHEBI:63063 cadmium cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63063 CHEBI:63069 neurosporaxanthin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63069 CHEBI:87017 1-gamma-linolenoyl 2-acylglycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87017 CHEBI:63068 octacarboxylic acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63068 CHEBI:63067 zeaxanthin bis(beta-D-glucoside) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63067 CHEBI:133221 2-oxindole-3-acetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133221 CHEBI:631 1-hydroxy-2-aminoethylphosphonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_631 CHEBI:133220 tuberonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133220 GO:0004745 retinol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004745 Reactome:R-HSA-2466832|RHEA:21284|EC:1.1.1.105|Reactome:R-HSA-2454081|Reactome:R-HSA-5362564|Reactome:R-HSA-5362721|Reactome:R-HSA-5362518|MetaCyc:RETINOL-DEHYDROGENASE-RXN microsomal retinol dehydrogenase activity|MDR|all-trans retinol dehydrogenase activity|retinol (vitamin A1) dehydrogenase activity|retinene reductase activity|retinol:NAD+ oxidoreductase activity|retinal reductase activity Catalysis of the reaction: retinol + NAD+ = retinal + NADH + H+. GO:0004744 retinal isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004744 RHEA:24124|KEGG_REACTION:R02126|MetaCyc:RETINAL-ISOMERASE-RXN all-trans-retinal 11-cis-trans-isomerase activity|retinene isomerase activity|retinoid isomerase activity Catalysis of the reaction: all-trans-retinal = 11-cis-retinal. GO:0004747 ribokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004747 RHEA:13697|Reactome:R-HSA-8955844|MetaCyc:RIBOKIN-RXN|EC:2.7.1.15 ATP:D-ribose 5-phosphotransferase activity|D-ribokinase activity|deoxyribokinase activity|ribokinase (phosphorylating) Catalysis of the reaction: ATP + D-ribose = ADP + D-ribose 5-phosphate. GO:0004746 riboflavin synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004746 KEGG_REACTION:R00066|MetaCyc:RIBOFLAVIN-SYN-RXN|RHEA:20772|EC:2.5.1.9 riboflavine synthetase activity|heavy riboflavin synthase|lumazine synthase activity|riboflavine synthase activity|vitamin B2 synthase activity|light riboflavin synthase|6,7-dimethyl-8-(1-D-ribityl)lumazine:6,7-dimethyl-8-(1-D-ribityl)lumazine 2,3-butanediyltransferase activity|riboflavin synthetase activity Catalysis of the reaction: 2 6,7-dimethyl-8-(1-D-ribityl)lumazine + H(+) = 5-amino-6-(D-ribitylamino)uracil + riboflavin. GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004741 Reactome:R-HSA-204169|MetaCyc:3.1.3.43-RXN|RHEA:12669|EC:3.1.3.43 pyruvate dehydrogenase phosphatase activity|pyruvate dehydrogenase (lipoamide)-phosphatase activity|[pyruvate dehydrogenase (lipoamide)] phosphatase, intrinsic catalyst activity|pyruvate dehydrogenase (lipoamide) phosphatase activity|phosphopyruvate dehydrogenase phosphatase activity|pyruvate dehydrogenase (lipoamide)-phosphate phosphohydrolase activity Catalysis of the reaction: [pyruvate dehydrogenase (lipoamide)] phosphate + H2O = [pyruvate dehydrogenase (lipoamide)] + phosphate. GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004740 MetaCyc:2.7.11.2-RXN|RHEA:23052|EC:2.7.11.2|Reactome:R-HSA-203946 [pyruvate dehydrogenase (lipoamide)] kinase activity|STK1|ATP:pyruvate dehydrogenase (acetyl-transferring) phosphotransferase activity|pyruvate dehydrogenase kinase activity|PDH kinase activity|PDK4|PDK3|PDK2|pyruvate dehydrogenase (lipoamide) kinase activity|pyruvate dehydrogenase kinase (phosphorylating) activity|PDK1|pyruvate dehydrogenase kinase activator protein activity|PDK|PDHK Catalysis of the reaction: ATP + pyruvate dehydrogenase (acetyl-transferring) = ADP + pyruvate dehydrogenase (acetyl-transferring) phosphate. CHEBI:63072 L-homocysteinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63072 GO:0004743 pyruvate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004743 EC:2.7.1.40|RHEA:18159|MetaCyc:PEPDEPHOS-RXN|Reactome:R-HSA-71670|Reactome:R-HSA-71670 phosphoenolpyruvate kinase activity|phosphoenol transphosphorylase activity|ATP:pyruvate 2-O-phosphotransferase activity Catalysis of the reaction: = ADP + H(+) + phosphoenolpyruvate => ATP + pyruvate. CHEBI:38071 1,3,5-triazine-2,4-diamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38071 GO:0004742 dihydrolipoyllysine-residue acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004742 EC:2.3.1.12 dihydrolipoic transacetylase activity|enzyme-dihydrolipoyllysine:acetyl-CoA S-acetyltransferase activity|acetyl-CoA: enzyme-6-N-(dihydrolipoyl)lysine S-acetyltransferase activity|lipoic acid acetyltransferase activity|acetyl-CoA:dihydrolipoamide S-acetyltransferase activity|dihydrolipoate acetyltransferase activity|thioltransacetylase A activity|lipoic transacetylase activity|acetyl-CoA: enzyme-N6-(dihydrolipoyl)lysine S-acetyltransferase activity|lipoate transacetylase activity|transacetylase X activity|lipoylacetyltransferase activity|lipoic acetyltransferase activity|lipoate acetyltransferase activity|dihydrolipoamide S-acetyltransferase activity|dihydrolipoyl acetyltransferase activity Catalysis of the reaction: acetyl-CoA + dihydrolipoamide = CoA + S-acetyldihydrolipoamide. CHEBI:38070 anti-arrhythmia drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38070 CHEBI:63070 beta-alaninate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63070 CHEBI:87044 4,4-dimethyl-5alpha-cholest-8-en-3beta-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87044 CHEBI:87046 4alpha-formyl-4beta-methyl-5alpha-8-cholesten-3beta-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87046 CHEBI:87045 4alpha-hydroxymethyl-4beta-methyl-5alpha-8-cholesten-3beta-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87045 CHEBI:87048 palmitoyllipid A(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87048 CHEBI:87047 3beta-hydroxy-4beta-methyl-5alpha-cholest-8-ene-4alpha-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87047 CHEBI:87049 lipid IVB(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87049 CHEBI:38063 quinolizines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38063 GO:0004749 ribose phosphate diphosphokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004749 EC:2.7.6.1|MetaCyc:PWY0-662|Reactome:R-HSA-111215|RHEA:15609|Reactome:R-HSA-73580|MetaCyc:PRPPSYN-RXN|KEGG_REACTION:R01049 PRPP synthetase activity|phosphoribosylpyrophosphate synthase activity|ribose-5-phosphate pyrophosphokinase activity|phosphoribosyl diphosphate synthetase activity|5-phosphoribosyl-alpha-1-pyrophosphate synthetase activity|phosphoribosyl pyrophosphate synthetase activity|ribophosphate pyrophosphokinase activity|phosphoribosyl-diphosphate synthetase activity|PP-ribose P synthetase activity|phosphoribosylpyrophosphate synthetase activity|pyrophosphoribosylphosphate synthetase activity|5-phosphoribosyl-1-pyrophosphate synthetase activity|5-phosphoribose pyrophosphorylase activity|ATP:D-ribose-5-phosphate diphosphotransferase activity|ribose-phosphate diphosphokinase activity|ribose-phosphate pyrophosphokinase activity|PPRibP synthetase activity Catalysis of the reaction: D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + 2 H(+). GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004748 Reactome:R-HSA-111804|EC:1.17.4.1|MetaCyc:RIBONUCLEOSIDE-DIP-REDUCTI-RXN|RHEA:23252|Reactome:R-HSA-111751 2'-deoxyribonucleoside-diphosphate:thioredoxin-disulfide 2'-oxidoreductase activity|2'-deoxyribonucleoside-diphosphate:oxidized-thioredoxin 2'-oxidoreductase activity Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin. CHEBI:38068 antimalarial biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38068 GO:0004756 selenide, water dikinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004756 UM-BBD_reactionID:r0833|MetaCyc:2.7.9.3-RXN|EC:2.7.9.3|RHEA:18737|KEGG_REACTION:R03595|Reactome:R-HSA-8959510 selenide,water dikinase activity|selenophosphate synthetase activity|selenophosphate synthase activity|selenium donor protein activity|ATP:selenide, water phosphotransferase activity Catalysis of the reaction: ATP + H(2)O + hydrogen selenide = AMP + 3 H(+) + phosphate + selenophosphorate. GO:0004755 saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004755 KEGG_REACTION:R02315|EC:1.5.1.10|RHEA:10020|MetaCyc:RXN3O-127 aminoadipate semialdehyde-glutamate reductase activity|6-N-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-glutamate-forming)|epsilon-N-(L-glutaryl-2)-L-lysine:NAD+(P) oxidoreductase (L-2-aminoadipate-semialdehyde forming)|aminoadipic semialdehyde-glutamate reductase activity|N6-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-glutamate-forming)|aminoadipic semialdehyde-glutamic reductase activity|saccharopine reductase activity|saccharopine (nicotinamide adenine dinucleotide phosphate, glutamate-forming) dehydrogenase activity Catalysis of the reaction: L-saccharopine + H(2)O + NADP(+) = L-allysine + L-glutamate + H(+) + NADPH. GO:0004758 serine C-palmitoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004758 EC:2.3.1.50|RHEA:14761|KEGG_REACTION:R01281|MetaCyc:SERINE-C-PALMITOYLTRANSFERASE-RXN|Reactome:R-HSA-428127 SPT|3-oxosphinganine synthetase activity|serine palmitoyltransferase|palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|acyl-CoA:serine C-2 acyltransferase decarboxylating Catalysis of the reaction: L-serine + H(+) + palmitoyl-CoA = 3-dehydrosphinganine + CO(2) + CoA. GO:0004757 sepiapterin reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004757 Reactome:R-HSA-1475414|RHEA:18953|MetaCyc:SEPIAPTERIN-REDUCTASE-RXN|Reactome:R-HSA-1497869|EC:1.1.1.153 7,8-dihydrobiopterin:NADP+ oxidoreductase activity Catalysis of the reaction: 7,8-dihydrobiopterin + NADP+ = sepiapterin + NADPH + H+. CHEBI:38084 sulfoximide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38084 GO:0004752 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004752 GO:0004751 ribose-5-phosphate isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004751 Reactome:R-HSA-5660015|RHEA:14657|KEGG_REACTION:R01056|EC:5.3.1.6|Reactome:R-HSA-177784|Reactome:R-HSA-5660013|Reactome:R-HSA-71306|MetaCyc:RIB5PISOM-RXN phosphoriboisomerase activity|D-ribose-5-phosphate ketol-isomerase activity|D-ribose 5-phosphate isomerase activity|phosphopentosisomerase activity|ribose phosphate isomerase activity|phosphopentoseisomerase activity|ribose 5-phosphate epimerase activity|D-ribose-5-phosphate aldose-ketose-isomerase activity|5-phosphoribose isomerase activity Catalysis of the reaction: D-ribose 5-phosphate = D-ribulose 5-phosphate. GO:0004754 saccharopine dehydrogenase (NAD+, L-lysine-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004754 KEGG_REACTION:R00715|MetaCyc:1.5.1.7-RXN|EC:1.5.1.7|RHEA:12440 6-N-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-lysine-forming)|dehydrogenase, saccharopine (nicotinamide adenine dinucleotide, lysine forming)|epsilon-N-(L-glutaryl-2)-L-lysine:NAD oxidoreductase (L-lysine forming)|N6-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-lysine-forming)|N6-(glutar-2-yl)-L-lysine:NAD oxidoreductase (L-lysine-forming) Catalysis of the reaction: L-saccharopine + H(2)O + NAD(+) = 2-oxoglutarate + L-lysine + H(+) + NADH. GO:0004753 saccharopine dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004753 lysine-ketoglutarate reductase activity|lysine-2-oxoglutarate reductase activity Catalysis of the cleavage of N6-(L-1,3-dicarboxypropyl)-L-lysine to release an amino acid (lysine or glutamate), with the concomitant reduction of an electron acceptor. CHEBI:87033 N-acyl-(4E,8E)-9-methylsphinga-4,8-dienine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87033 GO:0004750 ribulose-phosphate 3-epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004750 KEGG_REACTION:R01529|Reactome:R-HSA-199803|RHEA:13677|EC:5.1.3.1|Reactome:R-HSA-71303|MetaCyc:RIBULP3EPIM-RXN ribulose 5-phosphate 3-epimerase activity|D-ribulose 5-phosphate epimerase activity|erythrose-4-phosphate isomerase activity|phosphoketopentose epimerase activity|D-ribulose-5-P 3-epimerase activity|phosphoribulose epimerase activity|phosphoketopentose 3-epimerase activity|D-ribulose phosphate-3-epimerase activity|D-ribulose-5-phosphate epimerase activity|xylulose phosphate 3-epimerase activity|pentose-5-phosphate 3-epimerase activity|erythrose-4-phosphate epimerase activity|D-ribulose-5-phosphate 3-epimerase activity|D-xylulose-5-phosphate 3-epimerase activity Catalysis of the reaction: D-ribulose 5-phosphate = D-xylulose 5-phosphate. CHEBI:87034 aromatic fungicide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87034 CHEBI:87036 benzimidazole fungicide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87036 CHEBI:38077 polypyrrole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38077 CHEBI:38074 2-chloro-1,3,5-triazine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38074 GO:0004759 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004759 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004723 Reactome:R-HSA-2025882 calcineurin|calcium-dependent protein serine/threonine phosphatase, intrinsic catalyst activity Catalysis of the reactions: protein serine phosphate + H2O = protein serine + phosphate; and protein threonine phosphate + H2O = protein threonine + phosphate. These reactions require the presence of calcium ions. GO:0004722 protein serine/threonine phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004722 Reactome:R-HSA-199425|Reactome:R-HSA-8948139|Reactome:R-HSA-3002811|Reactome:R-HSA-429730|Reactome:R-HSA-380949|Reactome:R-HSA-9686524|Reactome:R-HSA-6792863|Reactome:R-HSA-3601585|Reactome:R-HSA-6811504|Reactome:R-HSA-5693153|Reactome:R-HSA-9660538|Reactome:R-HSA-163568|Reactome:R-HSA-9619449|Reactome:R-HSA-2187401|Reactome:R-HSA-201790|Reactome:R-HSA-2995388|Reactome:R-HSA-5687758|Reactome:R-HSA-5675431|Reactome:R-HSA-199959|Reactome:R-HSA-5672957|Reactome:R-HSA-4088141|Reactome:R-HSA-5675433|Reactome:R-HSA-9619467|Reactome:R-HSA-9660536|Reactome:R-HSA-209055|Reactome:R-HSA-5694421|Reactome:R-HSA-1295632|Reactome:R-HSA-4419948|Reactome:R-HSA-9658445|EC:3.1.3.16|Reactome:R-HSA-201787|Reactome:R-HSA-5679206|Reactome:R-HSA-5672961|Reactome:R-HSA-5692754|Reactome:R-HSA-9619430|Reactome:R-HSA-1638821|Reactome:R-HSA-5683405|Reactome:R-HSA-74948 protein phosphatase type 4, intrinsic catalyst activity|3-hydroxy 3-methylglutaryl coenzymeA reductase phosphatase|protein phosphatase X|phosphospectrin phosphatase|protein phosphatase type 2A, intrinsic catalyst activity|protein phosphatase type 2B, intrinsic catalyst activity|phosphatase 2B|phosphatase 2A|casein phosphatase|phosphatase IV|phosphopyruvate dehydrogenase phosphatase|phosphatase C-II|Aspergillus awamori acid protein phosphatase|BCKDH phosphatase|phosphatase H-II|protein phosphatase type 1 activity|phosphatase I|serine/threonine specific protein phosphatase activity|phosphatase III|phosphatase II|HMG-CoA reductase phosphatase|protein D phosphatase|protein phosphatase type 4 activity|phosphatase SP|polycation modulated (PCM-) phosphatase|calcineurin|protein phosphatase type 1, intrinsic catalyst activity|phosphatase IB|protein phosphatase type 2A activity|protein phosphatase type 2B activity|branched-chain alpha-keto acid dehydrogenase phosphatase|protein phosphatase type 2C activity Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate. GO:0004725 protein tyrosine phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004725 Reactome:R-HSA-8937767|Reactome:R-HSA-8864036|Reactome:R-HSA-74747|Reactome:R-HSA-997309|Reactome:R-HSA-8863804|Reactome:R-HSA-8867658|RHEA:10684|Reactome:R-HSA-8855381|Reactome:R-HSA-1169210|Reactome:R-HSA-8849435|Reactome:R-HSA-9636439|MetaCyc:PROTEIN-TYROSINE-PHOSPHATASE-RXN|Reactome:R-HSA-8864125|Reactome:R-HSA-377643|Reactome:R-HSA-8852200|Reactome:R-HSA-203797|Reactome:R-HSA-914036|Reactome:R-HSA-9698408|Reactome:R-HSA-202214|Reactome:R-HSA-997326|Reactome:R-HSA-997314|Reactome:R-HSA-6807027|Reactome:R-HSA-74748|Reactome:R-HSA-8864029|Reactome:R-HSA-997311|Reactome:R-HSA-74733|Reactome:R-HSA-9635461|Reactome:R-HSA-389758|Reactome:R-HSA-6807008|Reactome:R-HSA-8867047|Reactome:R-HSA-1549564|EC:3.1.3.48|Reactome:R-HSA-877308|Reactome:R-HSA-1169188|Reactome:R-HSA-9603719|Reactome:R-HSA-445089|Reactome:R-HSA-1169192|Reactome:R-HSA-391868|Reactome:R-HSA-5683967 phosphotyrosine histone phosphatase activity|phosphoprotein phosphatase (phosphotyrosine) activity|tyrosine O-phosphate phosphatase activity|[phosphotyrosine]protein phosphatase activity|phosphotyrosylprotein phosphatase activity|PTPase activity|PTP-phosphatase activity|tyrosylprotein phosphatase activity|protein-tyrosine-phosphate phosphohydrolase activity|PPT-phosphatase activity|phosphotyrosine phosphatase activity|protein-tyrosine-phosphatase activity|protein phosphotyrosine phosphatase activity|phosphotyrosine protein phosphatase activity Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate. GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004724 Catalysis of the reactions: protein serine phosphate + H2O = protein serine + phosphate; and protein threonine phosphate + H2O = protein threonine + phosphate. These reactions require the presence of magnesium. CHEBI:87061 carbamate fungicide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87061 GO:0004721 phosphoprotein phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004721 Reactome:R-HSA-174110|Reactome:R-HSA-1363276|Reactome:R-HSA-174124|Reactome:R-HSA-112383|MetaCyc:3.1.3.16-RXN|Reactome:R-HSA-167072|Reactome:R-HSA-178178|Reactome:R-HSA-2529015|Reactome:R-HSA-170161|Reactome:R-HSA-9636684|Reactome:R-HSA-170153|Reactome:R-HSA-170158|Reactome:R-HSA-1363274|Reactome:R-HSA-113503|Reactome:R-HSA-69199 protein phosphatase-2A activity|protein phosphatase-2B activity|protein phosphatase-2C activity|protein phosphatase-1 activity|protein phosphatase activity|phosphoprotein phosphohydrolase activity Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cell proteins and thereby provide an important mechanism for regulating cellular activity. CHEBI:87064 benzimidazolylcarbamate fungicide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87064 GO:0004720 protein-lysine 6-oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004720 RHEA:24544|Reactome:R-HSA-2395340|MetaCyc:PROTEIN-LYSINE-6-OXIDASE-RXN|EC:1.4.3.13|Reactome:R-HSA-2002466|Reactome:R-HSA-2129375 protein-L-lysine:oxygen 6-oxidoreductase (deaminating)|lysyl oxidase activity Catalysis of the reaction: peptidyl-L-lysyl-peptide + H2O + O2 = peptidyl-allysyl-peptide + NH3 + hydrogen peroxide. CHEBI:669 1-phenylethanol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_669 CHEBI:87068 imidazole fungicide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87068 CHEBI:87069 imidazole antifungal drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87069 GO:0004727 prenylated protein tyrosine phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004727 Catalysis of the reaction: prenylated-protein tyrosine phosphate + H2O = prenylated-protein tyrosine + phosphate. GO:0004726 non-membrane spanning protein tyrosine phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004726 Reactome:R-HSA-177924|Reactome:R-HSA-177923|Reactome:R-HSA-177926|Reactome:R-HSA-177935|Reactome:R-HSA-9635739 Catalysis of the reaction: non-membrane spanning protein tyrosine phosphate + H2O = non-membrane spanning protein tyrosine + phosphate. CHEBI:53680 dihalogenated L-tyrosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53680 GO:0004729 oxygen-dependent protoporphyrinogen oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004729 RHEA:25576|KEGG_REACTION:R03222|MetaCyc:PROTOPORGENOXI-RXN|EC:1.3.3.4|Reactome:R-HSA-189423 protoporphyrinogen-IX:oxygen oxidoreductase activity Catalysis of the reaction: 3 O(2) + protoporphyrinogen IX = 3 H(2)O(2) + protoporphyrin IX. GO:0004728 obsolete signal transducer, downstream of receptor, with protein tyrosine phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004728 receptor signaling protein tyrosine phosphatase activity|receptor signalling protein tyrosine phosphatase activity OBSOLETE. Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate. GO:0004734 pyrimidodiazepine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004734 RHEA:10720|MetaCyc:1.5.4.1-RXN|EC:1.5.4.1 PDA synthase activity|pyrimidodiazepine:glutathione-disulfide oxidoreductase (ring-opening, cyclizing) Catalysis of the reaction: a pyrimidodiazepine + oxidized glutathione = 6-pyruvoyltetrahydropterin + 2 glutathione. GO:0004733 pyridoxamine-phosphate oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004733 MetaCyc:PMPOXI-RXN|RHEA:15817|Reactome:R-HSA-965019|EC:1.4.3.5|Reactome:R-HSA-965079 pyridoxamine-5'-phosphate:oxygen oxidoreductase (deaminating)|pyridoxol-5'-phosphate:oxygen oxidoreductase (deaminating)|PMP oxidase activity|pyridoxine (pyridoxamine)phosphate oxidase activity|pyridoxine (pyridoxamine) 5'-phosphate oxidase activity|PdxH|pyridoxamine 5'-phosphate oxidase activity|pyridoxal 5'-phosphate synthase activity|pyridoxaminephosphate oxidase deaminating|pyridoxamine phosphate oxidase activity Catalysis of the reaction: pyridoxamine 5'-phosphate + H2O + O2 = pyridoxal 5'-phosphate + NH3 + hydrogen peroxide. GO:0004736 pyruvate carboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004736 Reactome:R-HSA-70501|RHEA:20844|MetaCyc:PYRUVATE-CARBOXYLASE-RXN|KEGG_REACTION:R00344|EC:6.4.1.1 pyruvate:carbon-dioxide ligase (ADP-forming)|pyruvic carboxylase activity Catalysis of the reaction: ATP + bicarbonate + pyruvate = ADP + 2 H(+) + oxaloacetate + phosphate. GO:0004735 pyrroline-5-carboxylate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004735 Reactome:R-HSA-6783939|Reactome:R-HSA-70664|RHEA:14109|Reactome:R-HSA-6783955|MetaCyc:PYRROLINECARBREDUCT-RXN|EC:1.5.1.2 L-proline-NAD(P)+ 5-oxidoreductase activity|1-pyrroline-5-carboxylate reductase activity|NADPH-L-delta1-pyrroline carboxylic acid reductase activity|L-proline:NAD(P)+ 5-oxidoreductase activity|L-proline oxidase activity|P5CR activity Catalysis of the reaction: L-proline + NADP+ = 1-pyrroline-5-carboxylate + NADPH + H+. CHEBI:87051 4alpha-methyl-5alpha-cholest-8-en-3beta-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87051 GO:0004730 pseudouridylate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004730 KEGG_REACTION:R01055|RHEA:18337|EC:4.2.1.70|MetaCyc:PSEUDOURIDYLATE-SYNTHASE-RXN pseudouridylate synthetase activity|pseudouridine monophosphate synthetase activity|pseudouridylic acid synthetase activity|pseudouridine-5'-phosphate glycosidase activity|uracil hydro-lyase (adding D-ribose 5-phosphate; pseudouridine-5'-phosphate-forming)|uracil hydrolyase activity|psiUMP synthetase activity|5-ribosyluracil 5-phosphate synthetase activity|pseudouridine monophosphate synthase activity|uracil hydro-lyase (adding D-ribose 5-phosphate) Catalysis of the reaction: D-ribose 5-phosphate + uracil = H(2)O + pseudouridine 5'-phosphate. CHEBI:87050 4alpha-methyl-5alpha-cholest-8-en-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87050 CHEBI:38060 triazine insecticide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38060 GO:0004732 pyridoxal oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004732 RHEA:23724|EC:1.2.3.8|MetaCyc:PYRIDOXAL-OXIDASE-RXN pyridoxal:oxygen 4-oxidoreductase activity Catalysis of the reaction: pyridoxal + H2O + O2 = 4-pyridoxate + hydrogen peroxide. CHEBI:87053 4alpha-hydroxymethyl-5alpha-cholest-8-en-3beta-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87053 GO:0004731 purine-nucleoside phosphorylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004731 Reactome:R-HSA-74242|Reactome:R-HSA-112034|Reactome:R-HSA-112033|RHEA:19805|Reactome:R-HSA-74249|EC:2.4.2.1|MetaCyc:PNP-RXN purine deoxyribonucleoside phosphorylase activity|PNPase activity|purine nucleoside phosphorylase activity|PUNPII|purine ribonucleoside phosphorylase activity|PUNPI|inosine-guanosine phosphorylase activity|inosine phosphorylase activity|purine-nucleoside:phosphate ribosyltransferase activity|purine deoxynucleoside phosphorylase activity Catalysis of the reaction: purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate. CHEBI:87055 3beta-hydroxy-5alpha-cholest-8-ene-4alpha-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87055 CHEBI:87054 4alpha-formyl-5alpha-cholest-8-en-3beta-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87054 CHEBI:87056 5alpha-cholest-8-en-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87056 CHEBI:87058 lipid IIB(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87058 GO:0004738 pyruvate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004738 MetaCyc:PYRUVOXID-RXN|MetaCyc:RXN0-1134|Reactome:R-HSA-71397 pyruvic acid dehydrogenase activity|pyruvic dehydrogenase activity Catalysis of the oxidative decarboxylation of pyruvate. GO:0004737 pyruvate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004737 RHEA:11628|MetaCyc:PYRUVATE-DECARBOXYLASE-RXN|EC:4.1.1.1 alpha-ketoacid carboxylase activity|pyruvic decarboxylase activity|2-oxo-acid carboxy-lyase (aldehyde-forming)|2-oxo-acid carboxy-lyase activity|alpha-carboxylase activity Catalysis of the reaction: a 2-oxo acid = an aldehyde + CO2. GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004739 RHEA:19189|EC:1.2.4.1 PDH|MtPDC (mitochondrial pyruvate dehydogenase complex) activity|pyruvate:dihydrolipoyllysine-residue acetyltransferase-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-acetylating)|pyruvate dehydrogenase complex activity|pyruvate dehydrogenase (lipoamide) activity|pyruvate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-acetylating) activity Catalysis of the reaction: pyruvate + lipoamide = S-acetyldihydrolipoamide + CO2. CHEBI:87080 N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-L-threonine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87080 GO:0004701 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004701 GO:0004700 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004700 GO:0004703 G protein-coupled receptor kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004703 RHEA:12008|EC:2.7.11.16 G-protein coupled receptor kinase activity|ATP:G-protein-coupled receptor phosphotransferase activity|G protein-coupled receptor kinase activity|GPCR kinase activity|GPCR phosphorylating protein kinase activity|G protein coupled receptor phosphorylating protein kinase activity|GRK6|GRK5|GRK4|G-protein-coupled receptor phosphorylating protein kinase activity|GPCRK|STK16 Catalysis of the reaction: ATP + G protein-coupled receptor = ADP + G protein-coupled receptor phosphate. CHEBI:87082 3-[beta-D-galactosyl-(1->6)-beta-D-galactosyl]-1,2-diacyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87082 GO:0004702 obsolete signal transducer, downstream of receptor, with serine/threonine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004702 EC:2.7.11.- receptor signaling protein serine/threonine kinase activity|receptor signalling protein serine/threonine kinase activity OBSOLETE. Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. CHEBI:53666 kaurane diterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53666 CHEBI:87089 2-O-(alpha-D-glucosyl)-sn-glycerol 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87089 CHEBI:685 1-organyl-2-acetyl-sn-glycero-3-phospholipid(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_685 CHEBI:38029 carbohydrate sulfonate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38029 CHEBI:38028 cyanuric acid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_38028 GO:0004709 MAP kinase kinase kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004709 Reactome:R-HSA-168184|Reactome:R-HSA-2730887|Reactome:R-HSA-450346|MetaCyc:2.7.11.25-RXN|Reactome:R-HSA-933530|Reactome:R-HSA-727819|EC:2.7.11.25|Reactome:R-HSA-450337|Reactome:R-HSA-451649|Reactome:R-HSA-392530 MAPK/ERK kinase kinase activity|MAP3K|MAPKKK activity|MEK kinase activity|MLK-like mitogen-activated protein triple kinase activity|MEKK3|REKS|MEKK2|MEKK1|MEKK|Mil/Raf|ATP:protein phosphotransferase (MAPKKKK-activated) activity|MLTK|cRaf|STK28|cMos|MLTKb|MEKK activity|mitogen-activated protein kinase kinase kinase activity|MLTKa Catalysis of the phosphorylation and activation of a MAP kinase kinase; each MAP kinase kinase can be phosphorylated by any of several MAP kinase kinase kinases. GO:0004708 MAP kinase kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004708 Reactome:R-HSA-3238999|Reactome:R-HSA-448951|MetaCyc:2.7.12.2-RXN|Reactome:R-HSA-450333|Reactome:R-HSA-5218804|Reactome:R-HSA-1247960|EC:2.7.12.2 MAPKK activity|MEK activity|MAP2K|MAPKK1|MAPKK|STK27|mitogen-activated protein kinase kinase activity|MKK|MKK7|MKK6|MAP kinase kinase 4 activity|ATP:protein phosphotransferase (MAPKKK-activated) activity|MKK4|MAP kinase kinase 7 activity|MAP kinase or ERK kinase activity|ERK activator kinase activity|MKK2|MAPK activator activity|MEK2|MEK1 Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate. CHEBI:53664 dehydroglycinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53664 GO:0004705 JUN kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004705 Reactome:R-HSA-204949|Reactome:R-HSA-205132|Reactome:R-HSA-9673789|Reactome:R-HSA-205075|Reactome:R-HSA-168136 SAPK1|JNK|JNK3alpha1|c-Jun N-terminal kinase activity Catalysis of the reaction: JUN + ATP = JUN phosphate + ADP. This reaction is the phosphorylation and activation of members of the JUN family, a gene family that encodes nuclear transcription factors. GO:0004704 NF-kappaB-inducing kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004704 NIK Catalysis of the phosphorylation of the alpha or beta subunit of the inhibitor of kappaB kinase complex (IKK). GO:0004707 MAP kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004707 Reactome:R-HSA-445079|Reactome:R-HSA-5654566|KEGG_REACTION:R00162|Reactome:R-HSA-73722|MetaCyc:2.7.11.24-RXN|Reactome:R-HSA-5654565|Reactome:R-HSA-9626832|Reactome:R-HSA-5654562|Reactome:R-HSA-451366|EC:2.7.11.24|Reactome:R-HSA-5654560|Reactome:R-HSA-111898|Reactome:R-HSA-198733 SAP kinase activity|MBP kinase I activity|ERK1|ERK2|SAPK|MBP kinase II activity|stress-activated protein kinase activity|myelin basic protein kinase activity|ERK|stress-activated kinase activity|MAPK|ATP:protein phosphotransferase (MAPKK-activated) activity|extracellular signal-regulated kinase activity|MAP kinase 1 activity|MAP kinase 2 activity|mitogen-activated protein kinase activity|mitogen activated kinase activity Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli. CHEBI:38024 carboxyalkyl sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38024 GO:0004706 JUN kinase kinase kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004706 JNKKK|JNK kinase kinase activity Catalysis of the reaction: JNKK + ATP = JNKK phosphate + ADP. This reaction is the phosphorylation and activation of JUN kinase kinases (JNKKs). CHEBI:38023 3-sulfolactic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38023 GO:0004712 protein serine/threonine/tyrosine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004712 Reactome:R-HSA-6802924|Reactome:R-HSA-6802927|Reactome:R-HSA-9656212|Reactome:R-HSA-6802918|EC:2.7.12.1|Reactome:R-HSA-6802921|Reactome:R-HSA-6802941|Reactome:R-HSA-6802910|Reactome:R-HSA-6802922|Reactome:R-HSA-5674373|Reactome:R-HSA-6802916|Reactome:R-HSA-5672969 dDYRK2|protein threonine/tyrosine kinase activity|dual-specificity kinase activity|dual-specificity protein kinase|Mps1p|ATP:protein phosphotransferase (Ser/Thr- and Tyr-phosphorylating) activity|Arabidopsis dual specificity kinase 1 activity|CLK1|ADK1 Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; ATP + a protein threonine = ADP + protein threonine phosphate; and ATP + a protein tyrosine = ADP + protein tyrosine phosphate. CHEBI:53659 EC 1.4.3.22 (diamine oxidase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53659 GO:0004711 ribosomal protein S6 kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004711 Catalysis of the reaction: ribosomal protein S6 + ATP = ribosomal protein S6 phosphate + ATP. GO:0004714 transmembrane receptor protein tyrosine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004714 Reactome:R-HSA-8950537|Reactome:R-HSA-8986994|Reactome:R-HSA-8983371|Reactome:R-HSA-177933|Reactome:R-HSA-169905|Reactome:R-HSA-8987042|Reactome:R-HSA-8987040|Reactome:R-HSA-8950591|Reactome:R-HSA-8950757|Reactome:R-HSA-8950453|Reactome:R-HSA-8983300|Reactome:R-HSA-8986995|Reactome:R-HSA-8987179|Reactome:R-HSA-8852552|Reactome:R-HSA-6784324|Reactome:R-HSA-8987096|EC:2.7.10.1|Reactome:R-HSA-8950364|Reactome:R-HSA-8987084|Reactome:R-HSA-74715|Reactome:R-HSA-198295|Reactome:R-HSA-8987129|Reactome:R-HSA-8983424|Reactome:R-HSA-8982163|Reactome:R-HSA-74711|Reactome:R-HSA-8950485|Reactome:R-HSA-8950423|Reactome:R-HSA-8983309|Reactome:R-HSA-8987070|RHEA:10596|Reactome:R-HSA-8986985|Reactome:R-HSA-74742|Reactome:R-HSA-8987012|Reactome:R-HSA-8987202|Reactome:R-HSA-8950354|Reactome:R-HSA-8950269|Reactome:R-HSA-8987150|Reactome:R-HSA-167683|Reactome:R-HSA-8950340|Reactome:R-HSA-8950405|Reactome:R-HSA-167019|Reactome:R-HSA-166544|Reactome:R-HSA-8853792|MetaCyc:2.7.10.1-RXN|Reactome:R-HSA-8987255|Reactome:R-HSA-8987141 neurite outgrowth regulating kinase activity|insulin receptor protein-tyrosine kinase activity|Drosophila Eph kinase activity|receptor protein tyrosine kinase activity|sevenless receptor activity|ATP:protein-L-tyrosine O-phosphotransferase (receptor-type) activity|neurotrophin TRKC receptor activity|anaplastic lymphoma kinase activity|neurotrophin TRKB receptor activity|neurotrophin TRKA receptor activity|ATP:protein-tyrosine O-phosphotransferase activity|neurotrophin TRK receptor activity|ephrin-B3 receptor tyrosine kinase activity|receptor protein-tyrosine kinase activity|novel oncogene with kinase-domain activity Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate. CHEBI:87071 conazole antifungal drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_87071 GO:0004713 protein tyrosine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004713 Reactome:R-HSA-983709|Reactome:R-HSA-3215391|Reactome:R-HSA-2038944|Reactome:R-HSA-8848606|Reactome:R-HSA-1250195|Reactome:R-HSA-5655270|Reactome:R-HSA-8875451|Reactome:R-HSA-8849042|Reactome:R-HSA-2130194|Reactome:R-HSA-1839098|Reactome:R-HSA-1839110|Reactome:R-HSA-2029453|Reactome:R-HSA-982807|Reactome:R-HSA-452097|Reactome:R-HSA-445076|Reactome:R-HSA-2586555|Reactome:R-HSA-354124|Reactome:R-HSA-9673756|Reactome:R-HSA-177930|Reactome:R-HSA-8847977|Reactome:R-HSA-373747|Reactome:R-HSA-9665411|Reactome:R-HSA-9680248|Reactome:R-HSA-3928610|Reactome:R-HSA-8848005|Reactome:R-HSA-5218828|Reactome:R-HSA-451942|Reactome:R-HSA-8849463|Reactome:R-HSA-9018572|Reactome:R-HSA-8956659|Reactome:R-HSA-2730858|Reactome:R-HSA-8948143|Reactome:R-HSA-1963581|Reactome:R-HSA-8848124|Reactome:R-HSA-429441|Reactome:R-HSA-1168394|Reactome:R-HSA-9706344|Reactome:R-HSA-2730886|Reactome:R-HSA-205289|Reactome:R-HSA-9665704|Reactome:R-HSA-6806974|Reactome:R-HSA-9613023|Reactome:R-HSA-9664278|Reactome:R-HSA-5218809|Reactome:R-HSA-1247844|Reactome:R-HSA-399934|Reactome:R-HSA-9026579|Reactome:R-HSA-2029268|Reactome:R-HSA-909730|Reactome:R-HSA-2671850|Reactome:R-HSA-389083|Reactome:R-HSA-429449|Reactome:R-HSA-428888|Reactome:R-HSA-909718|Reactome:R-HSA-9698003|Reactome:R-HSA-372693|Reactome:R-HSA-909732|Reactome:R-HSA-8875817|Reactome:R-HSA-1470009|Reactome:R-HSA-2023460|Reactome:R-HSA-182969|Reactome:R-HSA-2424484|Reactome:R-HSA-8848818|Reactome:R-HSA-9034875|Reactome:R-HSA-8874082|Reactome:R-HSA-9664261|Reactome:R-HSA-170156|Reactome:R-HSA-9606159|Reactome:R-HSA-391866|Reactome:R-HSA-1963586|Reactome:R-HSA-9670412|Reactome:R-HSA-2671829|Reactome:R-HSA-9670418|Reactome:R-HSA-9699578|Reactome:R-HSA-2424487|Reactome:R-HSA-391156|Reactome:R-HSA-388831|Reactome:R-HSA-5654149|Reactome:R-HSA-2404199|Reactome:R-HSA-191636|Reactome:R-HSA-5654655|Reactome:R-HSA-1839112|Reactome:R-HSA-5357429|Reactome:R-HSA-5607750|Reactome:R-HSA-9032426|Reactome:R-HSA-1433454|Reactome:R-HSA-9032854|Reactome:R-HSA-8848077|Reactome:R-HSA-374701|Reactome:R-HSA-8983872|Reactome:R-HSA-5654147|Reactome:R-HSA-2454208|Reactome:R-HSA-5654631|Reactome:R-HSA-3928583|Reactome:R-HSA-8937807|Reactome:R-HSA-9027272|Reactome:R-HSA-1248655|Reactome:R-HSA-1472121|Reactome:R-HSA-5624486|Reactome:R-HSA-4420117|Reactome:R-HSA-9028728|Reactome:R-HSA-2029459|Reactome:R-HSA-9027273|Reactome:R-HSA-5654407|Reactome:R-HSA-5218812|Reactome:R-HSA-8937728|Reactome:R-HSA-202168|Reactome:R-HSA-8964252|Reactome:R-HSA-8964242|Reactome:R-HSA-354073|Reactome:R-HSA-5654222|Reactome:R-HSA-1433542|Reactome:R-HSA-391865|Reactome:R-HSA-432129|Reactome:R-HSA-8876230|Reactome:R-HSA-9032601|Reactome:R-HSA-2012082|Reactome:R-HSA-202307|Reactome:R-HSA-112333|Reactome:R-HSA-2029989|Reactome:R-HSA-388833|Reactome:R-HSA-5655301|Reactome:R-HSA-873918|Reactome:R-HSA-8857925|Reactome:R-HSA-68954|Reactome:R-HSA-212710|Reactome:R-HSA-1225952|Reactome:R-HSA-391871|Reactome:R-HSA-8848758|Reactome:R-HSA-5218820|Reactome:R-HSA-9612996|Reactome:R-HSA-1839067|Reactome:R-HSA-2730862|Reactome:R-HSA-2730882|Reactome:R-HSA-190326|Reactome:R-HSA-5218851|Reactome:R-HSA-9606163|Reactome:R-HSA-177937|Reactome:R-HSA-5654428|Reactome:R-HSA-9703438|Reactome:R-HSA-508282|Reactome:R-HSA-5690702|Reactome:R-HSA-8853313|Reactome:R-HSA-879907|Reactome:R-HSA-1225960|Reactome:R-HSA-9665709|Reactome:R-HSA-4420128|Reactome:R-HSA-5654151|Reactome:R-HSA-2012087|Reactome:R-HSA-9665705|Reactome:R-HSA-9026890|Reactome:R-HSA-9664275|Reactome:R-HSA-5607745|Reactome:R-HSA-9625487|Reactome:R-HSA-202291|Reactome:R-HSA-2730888|Reactome:R-HSA-8849068|Reactome:R-HSA-418163|Reactome:R-HSA-3928594|Reactome:R-HSA-5654634|Reactome:R-HSA-5655243|Reactome:R-HSA-2395801|Reactome:R-HSA-377640|Reactome:R-HSA-443817|Reactome:R-HSA-5218640|Reactome:R-HSA-202165|Reactome:R-HSA-2029984|Reactome:R-HSA-1433506|Reactome:R-HSA-177934|Reactome:R-HSA-1888198|Reactome:R-HSA-1524186|Reactome:R-HSA-419646|Reactome:R-HSA-8874080|Reactome:R-HSA-380780|Reactome:R-HSA-2395412|Reactome:R-HSA-4420206|Reactome:R-HSA-1963582|Reactome:R-HSA-1433418|Reactome:R-HSA-5683930|Reactome:R-HSA-6790087|Reactome:R-HSA-2730884|Reactome:R-HSA-2730860|Reactome:R-HSA-2454239|Reactome:R-HSA-5655341|Reactome:R-HSA-202248|Reactome:R-HSA-202174|Reactome:R-HSA-418859|Reactome:R-HSA-373750|Reactome:R-HSA-2730833|Reactome:R-HSA-8874078|Reactome:R-HSA-445085|Reactome:R-HSA-8849102|Reactome:R-HSA-2424486|Reactome:R-HSA-5654408|Reactome:R-HSA-191062|Reactome:R-HSA-4093332|Reactome:R-HSA-418872|Reactome:R-HSA-9665032|Reactome:R-HSA-2033485|Reactome:R-HSA-5621355|Reactome:R-HSA-445091|Reactome:R-HSA-8937844|Reactome:R-HSA-9034714|Reactome:R-HSA-9695834|Reactome:R-HSA-9612085|Reactome:R-HSA-2586553|Reactome:R-HSA-399947|Reactome:R-HSA-8853309|EC:2.7.10.-|Reactome:R-HSA-8857583|Reactome:R-HSA-5654605|Reactome:R-HSA-5654628|Reactome:R-HSA-1169421|Reactome:R-HSA-190408|Reactome:R-HSA-9029155|Reactome:R-HSA-114600|Reactome:R-HSA-9664976|Reactome:R-HSA-2033488|Reactome:R-HSA-2038387|Reactome:R-HSA-2404193|Reactome:R-HSA-69195|Reactome:R-HSA-9603420|Reactome:R-HSA-9006323|Reactome:R-HSA-5654545|Reactome:R-HSA-202233|Reactome:R-HSA-9026464|Reactome:R-HSA-9634390|Reactome:R-HSA-8867041|Reactome:R-HSA-1671691|Reactome:R-HSA-2033486|Reactome:R-HSA-873919|Reactome:R-HSA-9037040|Reactome:R-HSA-5654418|Reactome:R-HSA-171011|Reactome:R-HSA-9032532|Reactome:R-HSA-8848873|Reactome:R-HSA-8857577|Reactome:R-HSA-452100|Reactome:R-HSA-8851933|Reactome:R-HSA-5621363|Reactome:R-HSA-3928604|Reactome:R-HSA-5637796|Reactome:R-HSA-9606162|Reactome:R-HSA-170070|Reactome:R-HSA-1433488|Reactome:R-HSA-9021609|Reactome:R-HSA-389086|Reactome:R-HSA-202216|Reactome:R-HSA-2428926|Reactome:R-HSA-8848975|Reactome:R-HSA-5654582|Reactome:R-HSA-2730843|Reactome:R-HSA-983707|Reactome:R-HSA-9026502|Reactome:R-HSA-5218642|Reactome:R-HSA-190429|Reactome:R-HSA-2197698|Reactome:R-HSA-389354|Reactome:R-HSA-912629|Reactome:R-HSA-6784319|Reactome:R-HSA-5654578|Reactome:R-HSA-9029151|Reactome:R-HSA-9006332|Reactome:R-HSA-9669911|Reactome:R-HSA-5654587|Reactome:R-HSA-3928580|Reactome:R-HSA-190427|Reactome:R-HSA-210291|Reactome:R-HSA-879925|Reactome:R-HSA-2201322|Reactome:R-HSA-909729|Reactome:R-HSA-9703437|Reactome:R-HSA-1839065|Reactome:R-HSA-983703|Reactome:R-HSA-9024726|Reactome:R-HSA-9669890|Reactome:R-HSA-2033490|Reactome:R-HSA-183058|Reactome:R-HSA-2023455|Reactome:R-HSA-9026510|Reactome:R-HSA-2012073|Reactome:R-HSA-186786|Reactome:R-HSA-2671742|Reactome:R-HSA-1251922|Reactome:R-HSA-452122|Reactome:R-HSA-5654575|Reactome:R-HSA-9665389|Reactome:R-HSA-5655268|Reactome:R-HSA-4420121|Reactome:R-HSA-1295609|Reactome:R-HSA-5686587|Reactome:R-HSA-8848776|Reactome:R-HSA-434836|Reactome:R-HSA-1982066|Reactome:R-HSA-170991|Reactome:R-HSA-873924|Reactome:R-HSA-190413|Reactome:R-HSA-1307963|Reactome:R-HSA-3928578|Reactome:R-HSA-445084|Reactome:R-HSA-2395439|Reactome:R-HSA-9033284|Reactome:R-HSA-174164|Reactome:R-HSA-2730851|Reactome:R-HSA-8848726|Reactome:R-HSA-5655278|Reactome:R-HSA-8857555|Reactome:R-HSA-2396594|Reactome:R-HSA-9604767|Reactome:R-HSA-8853315|Reactome:R-HSA-5218830|Reactome:R-HSA-5218806|Reactome:R-HSA-1248694|Reactome:R-HSA-5654397|Reactome:R-HSA-190388|Reactome:R-HSA-9027425|Reactome:R-HSA-1250348|Reactome:R-HSA-9011241|Reactome:R-HSA-5654653|Reactome:R-HSA-389762|Reactome:R-HSA-9034814|Reactome:R-HSA-873922|Reactome:R-HSA-8876948|Reactome:R-HSA-1250315|Reactome:R-HSA-8853325|Reactome:R-HSA-9666425|Reactome:R-HSA-9672175|Reactome:R-HSA-9664588|Reactome:R-HSA-8848436|Reactome:R-HSA-8855237|Reactome:R-HSA-5655284|Reactome:R-HSA-9672173|Reactome:R-HSA-9698005|Reactome:R-HSA-8851890|Reactome:R-HSA-202245|Reactome:R-HSA-2029449|Reactome:R-HSA-8942607|Reactome:R-HSA-190385|Reactome:R-HSA-3928627|Reactome:R-HSA-399946|Reactome:R-HSA-9673761|Reactome:R-HSA-210872|Reactome:R-HSA-1295540|Reactome:R-HSA-5654607|Reactome:R-HSA-9012650|Reactome:R-HSA-6784006|Reactome:R-HSA-5637795|Reactome:R-HSA-909726|Reactome:R-HSA-8849032|Reactome:R-HSA-8876246|Reactome:R-HSA-5621370|Reactome:R-HSA-879909|Reactome:R-HSA-9706350|Reactome:R-HSA-3928648 JAK|Janus kinase activity|protein-tyrosine kinase activity Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate. GO:0004710 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004710 CHEBI:87075 O-(N-acetyl-alpha-D-galactosaminyl)-L-threonine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87075 CHEBI:87079 N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-L-serine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87079 CHEBI:38038 sulfuric amide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38038 CHEBI:38033 acenaphthylenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38033 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004719 Reactome:R-HSA-5676966|RHEA:12705|EC:2.1.1.77|MetaCyc:2.1.1.77-RXN protein L-isoaspartyl methyltransferase activity|protein L-isoaspartate methyltransferase activity|protein D-aspartate methyltransferase activity|L-aspartyl/L-isoaspartyl protein methyltransferase activity|L-isoaspartyl protein carboxyl methyltransferase activity|D-aspartyl/L-isoaspartyl methyltransferase activity|protein beta-aspartate O-methyltransferase activity|protein (D-aspartate) methyltransferase activity|L-isoaspartyl/D-aspartyl protein carboxyl methyltransferase activity|protein-L-isoaspartate O-methyltransferase activity|S-adenosyl-L-methionine:protein-L-isoaspartate O-methyltransferase activity|protein O-methyltransferase (L-isoaspartate)|protein-beta-aspartate O-methyltransferase activity|protein-L-isoaspartate(D-aspartate) O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + protein L-beta-aspartate = S-adenosyl-L-homocysteine + protein L-beta-aspartate methyl ester. CHEBI:38032 carbotricyclic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38032 CHEBI:38031 carboxyalkanesulfonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38031 GO:0004716 obsolete signal transducer, downstream of receptor, with protein tyrosine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004716 EC:2.7.10.- receptor signalling protein tyrosine kinase activity|receptor signaling protein tyrosine kinase activity OBSOLETE. Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate. GO:0004715 non-membrane spanning protein tyrosine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004715 Reactome:R-HSA-1168459|Reactome:R-HSA-1295519|Reactome:R-HSA-1168423|Reactome:R-HSA-1112602|Reactome:R-HSA-453200|Reactome:R-HSA-432148|Reactome:R-HSA-437936|Reactome:R-HSA-6786095|EC:2.7.10.2|Reactome:R-HSA-1369115|Reactome:R-HSA-6786096|Reactome:R-HSA-1112703|Reactome:R-HSA-6788582|Reactome:R-HSA-1168767|Reactome:R-HSA-8871373|MetaCyc:2.7.10.2-RXN|Reactome:R-HSA-879910 focal adhesion kinase activity|cytoplasmic protein tyrosine kinase activity|janus kinase 1 activity|janus kinase 2 activity|janus kinase 3 activity|ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|ATP:protein-tyrosine O-phosphotransferase activity|non-specific protein-tyrosine kinase activity|p60c-src protein tyrosine kinase activity|Bruton's tyrosine kinase activity Catalysis of the reaction: ATP + protein L-tyrosine = ADP + protein L-tyrosine phosphate by a non-membrane spanning protein. CHEBI:38036 sulfobenzoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38036 CHEBI:14086 dTDP-D-galactose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_14086 GO:0004718 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004718 CHEBI:53650 guaiacylglycerol-beta-guaiacyl ether biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_53650 GO:0004717 obsolete focal adhesion kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004717 focal adhesion kinase activity|FAK OBSOLETE. (Was not defined before being made obsolete). CHEBI:38034 aminonaphthalene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38034 CHEBI:77619 1,3-dipalmitoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77619 CHEBI:77618 norajmaline(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77618 CHEBI:77617 senecionine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77617 GO:0038137 ERBB4-EGFR signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038137 ERBB4-EGFR signalling pathway|ERBB1-ERBB4 signaling pathway|HER1-HER4 signaling pathway A series of molecular signals transmitted by a heterodimeric complex of the tyrosine kinase receptors EGFR (epidermal growth factor receptor/ERBB1) and ERBB4. The pathway begins with binding of a ligand to either cell surface receptor, or the dimeric receptor complex, and ends with regulation of a downstream cellular process, e.g. transcription. GO:0038136 ERBB3-ERBB4 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038136 HER3-HER4 signaling pathway|ERBB3-ERBB4 signalling pathway A series of molecular signals transmitted by a heterodimeric complex of the tyrosine kinase receptors ERBB3 and ERBB4. The pathway begins with binding of a ligand to either cell surface receptor, or the dimeric receptor complex, and ends with regulation of a downstream cellular process, e.g. transcription. GO:0038139 ERBB4-EGFR complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0038139 ERBB4:EGFR heterodimer|EGFR-ERBB4 complex A heterodimeric complex between the tyrosine kinase receptors ERBB4 (also called HER4) and epidermal growth factor receptor (EGFR/ERBB1). GO:0038138 ERBB4-ERBB4 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038138 HER4-HER4 signaling pathway|ERBB4 homodimeric signaling pathway|ERBB4-ERBB4 signalling pathway A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB4, followed by ligand-induced homodimerization of ERBB4 and transmission of the signal into the cell by the homodimeric ERBB4 complex. The pathway ends with regulation of a downstream cellular process, e.g. transcription. CHEBI:133291 saturated dicarboxylic acid dianion(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133291 GO:0038131 neuregulin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038131 NRG receptor activity|NRG2 receptor activity|NRG1 receptor activity Combining with a neuregulin, a member of the EGF family of growth factors, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0038130 ERBB4 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038130 HER4 signaling pathway|receptor tyrosine-protein kinase erbB-4 signaling pathway|ERBB4 signalling pathway A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB4 on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription. CHEBI:133292 3-oxo fatty acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133292 CHEBI:77612 cis,cis-2-ammonio-3-(3-oxoprop-1-enyl)but-2-enedioate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77612 GO:0038133 ERBB2-ERBB3 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038133 ERBB2-ERBB3 signalling pathway|HER2-HER3 signaling pathway A series of molecular signals initiated by binding of a ligand to a ERBB3 receptor on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and ERBB3. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB3. ERBB3 also has impaired kinase activity and relies on ERBB2 for activation and signal transmission. CHEBI:77611 monoalk-1-enyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77611 GO:0038132 neuregulin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038132 Interacting selectively and non-covalently with a neuregulin, a member of the EGF family of growth factors. CHEBI:133294 oxo dicarboxylic acid dianion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133294 GO:0038135 ERBB2-ERBB4 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038135 HER2-HER4 signaling pathway|ERBB2-ERBB4 signalling pathway A series of molecular signals initiated by binding of a ligand to a ERBB4 receptor on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and ERBB4. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB4. GO:0038134 ERBB2-EGFR signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038134 EGFR-HER2 signaling pathway|ERBB2-EGFR signalling pathway A series of molecular signals initiated by binding of a ligand to an epidermal growth factor receptor (EGFR/ERBB1) on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and EGFR. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as EGFR. CHEBI:77624 1-palmitoyl-3-stearoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77624 GO:0038126 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0038126 GO:0038125 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0038125 GO:0038128 ERBB2 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038128 HER2 signaling pathway|ERBB2 signalling pathway|receptor tyrosine-protein kinase erbB-2 signaling pathway|NEU signaling A series of molecular signals initiated by binding of a ligand to a member of the ERBB family of receptors on the surface of a cell, where the signal is transmitted by ERBB2. The pathway ends with regulation of a downstream cellular process, e.g. transcription. ERBB2 receptors are themselves unable to bind to ligands, but act as a signal-amplifying tyrosine kinase within a heterodimeric pair. GO:0038127 ERBB signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038127 EGFR family signaling pathway|ErbB signaling|EGF receptor family signaling pathway|ERBB signalling pathway A series of molecular signals initiated by binding of a ligand to a member of the ERBB family of receptor tyrosine kinases on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0038129 ERBB3 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038129 ERBB3 signalling pathway|HER3 signaling pathway|receptor tyrosine-protein kinase erbB-3 signaling pathway A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB3 on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription. ERBB3 receptors have impaired kinase activity and rely on the kinase activity of the heterodimer partner for activation and signal transmission. GO:0038120 CCL21-activated CCR7 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038120 CCL21-activated CCR7 signalling pathway A series of molecular signals initiated by the binding of the C-C chemokine CCL21 to a C-C chemokine type 7 receptor (CCR7) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0038122 C-C motif chemokine 5 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038122 small inducible cytokine A5 receptor activity|RANTES receptor activity|CCL5 receptor activity Combining with the C-C motif chemokine 5 (CCL5) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. CHEBI:77623 1-palmitoyl-2-oleoyl-3-stearoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77623 GO:0038121 C-C motif chemokine 21 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038121 CCL21 receptor activity Combining with the C-C motif chemokine 21 (CCL21) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. CHEBI:77622 2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77622 GO:0038124 toll-like receptor TLR6:TLR2 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038124 toll-like receptor TLR6:TLR2 signalling pathway|TLR2:TLR6 signaling pathway A series of molecular signals initiated by the binding of a heterodimeric TLR6:TLR2 complex to one of it's physiological ligands, followed by transmission of the signal by the activated receptor, and ending with regulation of a downstream cellular process, e.g. transcription. CHEBI:77621 2',3,4,4',6'-pentahydroxychalcone(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77621 GO:0038123 toll-like receptor TLR1:TLR2 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038123 TLR2:TLR1 signaling pathway|toll-like receptor TLR1:TLR2 signalling pathway A series of molecular signals initiated by the binding of a heterodimeric TLR1:TLR2 complex to one of it's physiological ligands, followed by transmission of the signal by the activated receptor, and ending with regulation of a downstream cellular process, e.g. transcription. CHEBI:77620 5-oxido-6-methylpyridinium-3,4-dicarboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77620 CHEBI:77638 dihydrophloroglucinol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77638 CHEBI:77636 fatty acyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77636 CHEBI:77639 sulochrin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77639 GO:0038115 chemokine (C-C motif) ligand 19 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038115 CCL19-mediated signaling pathway|C-C chemokine receptor type 7 signaling pathway|chemokine (C-C motif) ligand 19 signalling pathway A series of molecular signals initiated by the binding of the C-C chemokine CCL19 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0038114 interleukin-21-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038114 interleukin-21-mediated signalling pathway|IL-21-mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-21 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0038117 C-C motif chemokine 19 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038117 CCL19 receptor activity Combining with the C-C motif chemokine 19 (CCL19) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0038116 chemokine (C-C motif) ligand 21 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038116 CCL21-mediated signaling pathway|chemokine (C-C motif) ligand 21 signalling pathway|C-C chemokine receptor type 7 signaling pathway A series of molecular signals initiated by the binding of the C-C chemokine CCL21 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0038119 CCL19-activated CCR7 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038119 CCL19-activated CCR7 signalling pathway A series of molecular signals initiated by the binding of the C-C chemokine CCL19 to a C-C chemokine type 7 receptor (CCR7) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0038118 C-C chemokine receptor CCR7 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038118 C-C chemokine receptor CCR7 signalling pathway|CCR7 signaling pathway A series of molecular signals initiated by a the C-C chemokine type 7 receptor on the surface of a cell binding to one of it's physiological ligands, and ending with regulation of a downstream cellular process, e.g. transcription. CHEBI:77630 trans-2-pentadecenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77630 GO:0038111 interleukin-7-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038111 interleukin-7-mediated signalling pathway|IL-7-mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-7 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. CHEBI:77634 2-aminomuconic 6-semialdehyde zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77634 GO:0038110 interleukin-2-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038110 interleukin-2-mediated signalling pathway|IL-2-mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-2 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. CHEBI:77633 isonocardicin A(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77633 GO:0038113 interleukin-9-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038113 IL-9-mediated signaling pathway|interleukin-9-mediated signalling pathway A series of molecular signals initiated by the binding of interleukin-9 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. CHEBI:77632 unsaturated fatty acyl-CoA(4-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77632 GO:0038112 interleukin-8-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038112 interleukin-8-mediated signalling pathway|IL-8-mediated signaling pathway A series of molecular signals initiated by the binding of interleukin-8 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. CHEBI:77631 1-piperideine-2-carboxylic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77631 CHEBI:77648 novapikromycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77648 CHEBI:77647 2,3',4,6-tetrahydroxybenzophenone(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77647 CHEBI:77646 2-oleoyl-sn-glycero-3-phosphoserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77646 CHEBI:63001 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_63001 GO:0038104 nodal receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0038104 ActRIIB.ALK4.EGF-CFC complex A protein complex containing at least a type II activin receptor, a type I activin receptor, and a coreceptor (EGF-CFC protein) such as Cripto or Cryptic. Nodal receptor complexes are capable of binding a nodal protein and transducing the signal into the cell. GO:0038103 activin receptor antagonist activity involved in negative regulation of nodal signaling pathway biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038103 nodal antagonist activity|activin receptor antagonist activity involved in negative regulation of nodal signalling pathway Interacting with an activin receptor to reduce the action of the agonist nodal. A receptor antagonist does not initiate signaling upon binding to a receptor, but instead blocks an agonist from binding to the receptor. GO:0038106 choriogonadotropin hormone binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038106 chorionic gonadotropin binding|chorionic gonadotrophin binding Interacting selectively and non-covalently with choriogonadotropin hormone, a heterodimer, with an alpha subunit identical to that of luteinizing hormone (LH), follicle-stimulating hormone (FSH) and thyroid-stimulating hormone (TSH), and a unique beta subunit. GO:0038105 sequestering of TGFbeta from receptor via TGFbeta binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038105 extracellular sequestering of transforming growth factor-beta|extracellular sequestering of TGFbeta Binding to a transforming growth factor-beta (TGFbeta) protein in the extracellular region, and inhibiting TGFbeta signaling by preventing TGFbeta from binding to its cell surface receptor. GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038108 reduction of appetite by leptin-mediated signaling|inhibition of appetite by leptin signaling|suppression of appetite by leptin-mediated signaling pathway|negative regulation of appetite by leptin-mediated signalling pathway A series of molecular signals initiated by the binding of leptin to a receptor on the surface of a cell, which reduces appetite, the desire or physical craving for food. GO:0038107 nodal signaling pathway involved in determination of left/right asymmetry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038107 nodal signalling pathway involved in determination of left/right asymmetry|regulation of transcription from RNA polymerase II promoter by nodal signaling pathway, involved in determination of left/right symmetry A series of molecular signals initiated by the binding of a nodal protein to an activin receptor on the surface of a target cell, which contributes to the establishment of an organism's body plan or part of an organism with respect to the left and right halves. GO:0038109 Kit signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038109 Kit signalling pathway|stem cell factor signaling pathway|SCF signaling pathway|stem cell factor receptor signaling pathway A series of molecular signals that starts with the binding of stem cell factor to the tyrosine kinase receptor KIT on the surface of a cell, and ends with regulation of a downstream cellular process, e.g. transcription. Stem cell factor (KIT ligand) binding to the receptor Kit mediates receptor dimerization, activation of its intrinsic tyrosine kinase activity and autophosphorylation. The activated receptor then phosphorylates various substrates, thereby activating distinct signaling cascades within the cell that trigger a change in state or activity of the cell. CHEBI:77641 anthocyanidin 3,5-diglucoside betaine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77641 CHEBI:77640 apiin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77640 GO:0038100 nodal binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038100 Interacting selectively and non-covalently with a nodal protein, a member of the transforming growth factor-beta superfamily. CHEBI:77645 2',4,4',6'-tetrahydroxychalcone(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77645 CHEBI:77644 5-L-glutamyl amino acid(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77644 CHEBI:77643 protoaphin aglucone(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77643 GO:0038102 activin receptor antagonist activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038102 Interacting with an activin receptor complex to reduce the action of another ligand, the agonist. A receptor antagonist does not initiate signaling upon binding to a receptor, but instead blocks an agonist from binding to the receptor. GO:0038101 sequestering of nodal from receptor via nodal binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038101 nodal antagonist activity|extracellular regulation of nodal|binding to and sequestering nodal Binding to a nodal protein in the extracellular region, and inhibiting nodal signaling by preventing nodal from binding to its cell surface receptor. CHEBI:77642 2'-O-methyllicodione(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77642 CHEBI:77659 emodin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77659 CHEBI:77658 nocardicin A(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77658 CHEBI:77657 5-amino-1-(5-phosphonato-D-ribosyl)imidazolium-4-carboxylate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77657 CHEBI:77652 novamethymycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77652 CHEBI:133251 3-hydroxydicarboxylate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133251 CHEBI:77656 4-oxoproline zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77656 CHEBI:77654 EC 1.1.1.267 (1-deoxy-D-xylulose-5-phosphate reductoisomerase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77654 CHEBI:77653 (3R)-3-carboxy-3-hydroxypropanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77653 CHEBI:77663 pulcherriminate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77663 CHEBI:77662 L-3-oxoalanine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77662 CHEBI:77660 pyrroloquinoline quinol(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77660 CHEBI:77667 2,4-divinyl protochlorophyllide a(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77667 GO:0004789 thiamine-phosphate diphosphorylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004789 MetaCyc:THI-P-SYN-RXN|RHEA:22328|KEGG_REACTION:R03223|EC:2.5.1.3 TMP pyrophosphorylase activity|thiamine-phosphate pyrophosphorylase activity|TMP diphosphorylase activity|thiamine monophosphate pyrophosphorylase activity|TMP-PPase activity|thiamine phosphate pyrophosphorylase activity|2-methyl-4-amino-5-hydroxymethylpyrimidine-diphosphate:4-methyl-5-(2-phosphoethyl)thiazole 2-methyl-4-aminopyrimidine-5-methenyltransferase activity|thiamin-phosphate pyrophosphorylase activity|thiamin-phosphate diphosphorylase activity|thiamine-phosphate synthase activity Catalysis of the reaction: 4-amino-2-methyl-5-diphosphomethylpyrimidine + 4-methyl-5-(2-phosphoethyl)-thiazole + H(+) = diphosphate + thiamine phosphate. GO:0004788 thiamine diphosphokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004788 MetaCyc:THIAMIN-PYROPHOSPHOKINASE-RXN|RHEA:11576|EC:2.7.6.2|Reactome:R-HSA-196761 thiaminokinase activity|thiamin pyrophosphotransferase activity|ATP:thiamine diphosphotransferase activity|thiamine pyrophosphokinase activity|TPTase activity|thiamin pyrophosphokinase activity|thiamin diphosphokinase activity|thiamin:ATP pyrophosphotransferase activity|ATP:thiamin pyrophosphotransferase activity Catalysis of the reaction: ATP + thiamine = AMP + thiamine diphosphate. CHEBI:77679 1-hexadecyl-2-acetyl-3-decanoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77679 GO:0004785 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004785 GO:0004784 superoxide dismutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004784 Reactome:R-HSA-3299680|MetaCyc:SUPEROX-DISMUT-RXN|Reactome:R-HSA-3299691|Reactome:R-HSA-3299682|Reactome:R-HSA-3777112|Reactome:R-HSA-1222469|RHEA:20696|Reactome:R-HSA-1222462|EC:1.15.1.1 nickel superoxide dismutase activity|erythrocuprein|hemocuprein|iron superoxide dismutase activity|cuprein|ferrisuperoxide dismutase activity|SOD-4|SOD-3|SOD-2|hepatocuprein|Cu-Zn superoxide dismutase activity|manganese superoxide dismutase activity|SOD-1|superoxide:superoxide oxidoreductase activity|SODS|Cu,Zn-SOD|SOD|nickel superoxide oxidoreductase|iron superoxide oxidoreductase|superoxide dismutase II|cytocuprein|superoxide dismutase I|zinc superoxide oxidoreductase|Mn, Fe superoxide dismutase|copper, zinc superoxide dismutase activity|SODF|Mn-SOD|manganese superoxide oxidoreductase|Fe-SOD Catalysis of the reaction: 2 superoxide + 2 H+ = O2 + hydrogen peroxide. GO:0004787 thiamine-diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004787 thiamin pyrophosphatase activity|thiaminpyrophosphatase activity|thiamin-pyrophosphatase activity|TPPase activity|thiamine pyrophosphatase activity Catalysis of the reaction: TDP + H2O = TMP + phosphate. GO:0004786 obsolete Mn, Fe superoxide dismutase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004786 Mn, Fe superoxide dismutase OBSOLETE. (Was not defined before being made obsolete). GO:0004781 sulfate adenylyltransferase (ATP) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004781 Reactome:R-HSA-174392|EC:2.7.7.4|MetaCyc:SULFATE-ADENYLYLTRANS-RXN|RHEA:18133|Reactome:R-HSA-3560794 ATP:sulfate adenylyltransferase activity|sulfate adenylate transferase activity|ATP-sulfurylase activity|adenosine-5'-triphosphate sulfurylase activity|sulphate adenylyltransferase (ATP) activity|ATP sulfurylase activity|adenylylsulfate pyrophosphorylase activity|sulfurylase activity|adenosinetriphosphate sulfurylase activity Catalysis of the reaction: ATP + sulfate = diphosphate + adenylylsulfate. CHEBI:87000 1-acyl-2-[(7Z)-hexadec-7-enoyl]-glycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87000 GO:0004780 sulfate adenylyltransferase (ADP) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004780 RHEA:16529|EC:2.7.7.5|KEGG_REACTION:R00530|MetaCyc:SULFATE-ADENYLYLTRANSFERASE-ADP-RXN adenosine diphosphate sulfurylase activity|sulfate (adenosine diphosphate) adenylyltransferase activity|ADP:sulfate adenylyltransferase activity|ADP-sulfurylase activity|sulphate adenylyltransferase (ADP) activity Catalysis of the reaction: ADP + H(+) + sulfate = 5'-adenylyl sulfate + phosphate. GO:0004783 sulfite reductase (NADPH) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004783 MetaCyc:SULFITE-REDUCT-RXN|RHEA:13801|EC:1.8.1.2 NADPH-dependent sulfite reductase activity|NADPH:sulfite reductase flavoprotein|NADPH-sulfite reductase activity|sulfite (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|hydrogen-sulfide:NADP+ oxidoreductase activity|sulphite reductase (NADPH) activity|H2S-NADP oxidoreductase activity Catalysis of the reaction: hydrogen sulfide + 3 NADP+ + 3 H2O = sulfite + 3 NADPH + 3 H+. CHEBI:87002 1-acyl-2-[(3E)-hexadec-3-enoyl]-glycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87002 GO:0004782 sulfinoalanine decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004782 EC:4.1.1.29|RHEA:16877|Reactome:R-HSA-1655443|MetaCyc:SULFINOALANINE-DECARBOXYLASE-RXN CSADCase activity|cysteinesulfinate decarboxylase activity|3-sulfino-L-alanine carboxy-lyase activity|3-sulfino-L-alanine carboxy-lyase (hypotaurine-forming)|cysteic decarboxylase activity|L-cysteinesulfinic acid decarboxylase activity|cysteinesulfinic acid decarboxylase activity|CSAD|CADCase/CSADCase activity|sulfoalanine decarboxylase activity|cysteine-sulfinate decarboxylase activity|sulphinoalanine decarboxylase activity Catalysis of the reaction: 3-sulfino-L-alanine = hypotaurine + CO2. CHEBI:87003 1-acyl-2-palmitoleoylglycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87003 CHEBI:87008 1-oleoyl-2-acylglycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87008 CHEBI:87007 1-stearoyl 2-acylglycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_87007 CHEBI:77670 primary fluorescent chlorophyll catabolite(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77670 CHEBI:77674 queuine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77674 CHEBI:77673 N-acyl-L-phenylalanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77673 CHEBI:77672 N-acyl-D-phenylalanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77672 CHEBI:77671 luteolin 7-O-beta-D-glucosiduronate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77671 CHEBI:77678 1-palmityl-2-acetyl-3-myristoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77678 CHEBI:77677 1-palmityl-2-acetyl-3-stearoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77677 CHEBI:77676 1-palmityl-2-acetyl-3-linoleoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77676 GO:0004799 thymidylate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004799 RHEA:12104|KEGG_REACTION:R02101|Reactome:R-HSA-73605|MetaCyc:THYMIDYLATESYN-RXN|EC:2.1.1.45 5,10-methylenetetrahydrofolate:dUMP C-methyltransferase activity|methylenetetrahydrofolate:dUMP C-methyltransferase activity|dTMP synthase activity|thymidylate synthetase activity|TMP synthetase activity Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP = 7,8-dihydrofolate + thymidylate. GO:0004796 thromboxane-A synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004796 KEGG_REACTION:R02268|RHEA:17137|Reactome:R-HSA-5603275|Reactome:R-HSA-76500|EC:5.3.99.5|MetaCyc:THROMBOXANE-A-SYNTHASE-RXN (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate thromboxane-A2-isomerase activity|cytochrome P450 CYP5|thromboxane synthetase activity|(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate isomerase activity|thromboxane synthase activity Catalysis of the reaction: prostaglandin H(2) = thromboxane A(2). GO:0004795 threonine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004795 RHEA:10840|MetaCyc:THRESYN-RXN|EC:4.2.3.1 threonine synthetase activity|O-phospho-L-homoserine phospho-lyase (adding water)|O-phospho-L-homoserine phospho-lyase (adding water; L-threonine-forming) Catalysis of the reaction: O-phospho-L-homoserine + H2O = L-threonine + phosphate. GO:0004798 thymidylate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004798 RHEA:13517|EC:2.7.4.9|MetaCyc:DTMPKI-RXN ATP:dTMP phosphotransferase activity|thymidine 5'-monophosphate kinase activity|thymidine monophosphate kinase activity|thymidylate monophosphate kinase activity|dTMP kinase activity|deoxythymidine 5'-monophosphate kinase activity|thymidylic kinase activity|TMPK activity|thymidylic acid kinase activity Catalysis of the reaction: ATP + thymidine 5'-phosphate = ADP + thymidine 5'-diphosphate. GO:0004797 thymidine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004797 MetaCyc:THYKI-RXN|EC:2.7.1.21|RHEA:19129 ATP:thymidine 5'-phosphotransferase activity|deoxythymidine kinase (phosphorylating)|thymidine kinase (phosphorylating)|2'-deoxythymidine kinase activity Catalysis of the reaction: ATP + thymidine = ADP + thymidine 5'-phosphate. GO:0004792 thiosulfate sulfurtransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004792 MetaCyc:THIOSULFATE-SULFURTRANSFERASE-RXN|Reactome:R-HSA-9013198|EC:2.8.1.1|RHEA:16881|KEGG_REACTION:R01931 thiosulphate sulphurtransferase activity|thiosulfate thiotransferase activity|thiosulfate cyanide transsulfurase activity|thiosulfate:cyanide sulfurtransferase activity|rhodanase activity|rhodanese activity Catalysis of the reaction: hydrogen cyanide + thiosulfate = H(+) + sulfite + thiocyanate. GO:0004791 thioredoxin-disulfide reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004791 RHEA:20345|Reactome:R-HSA-3323050|EC:1.8.1.9|KEGG_REACTION:R02016|Reactome:R-HSA-9617735|Reactome:R-HSA-1222485|MetaCyc:THIOREDOXIN-REDUCT-NADPH-RXN|Reactome:R-HSA-73646 NADP--thioredoxin reductase activity|NADPH2:oxidized thioredoxin oxidoreductase activity|NADPH:oxidized thioredoxin oxidoreductase activity|thioredoxin reductase (NADPH) activity|thioredoxin disulfide reductase activity|thioredoxin-disulphide reductase activity|NADPH--thioredoxin reductase activity|thioredoxin:NADP+ oxidoreductase activity Catalysis of the reaction: NADP(+) + thioredoxin = H(+) + NADPH + thioredoxin disulfide. CHEBI:615 1-carbapenem-3-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_615 GO:0004794 L-threonine ammonia-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004794 UM-BBD_reactionID:r0433|EC:4.3.1.19|MetaCyc:THREDEHYD-RXN|RHEA:22108 L-threonine hydro-lyase (deaminating) activity|L-threonine dehydratase activity|L-threonine deaminase activity|threonine deaminase activity|L-serine dehydratase activity|serine deaminase activity|threonine ammonia-lyase activity|threonine dehydrase activity|L-threonine ammonia-lyase (2-oxobutanoate-forming)|threonine dehydratase activity Catalysis of the reaction: L-threonine = 2-oxobutanoate + NH3. GO:0004793 threonine aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004793 RHEA:19625|EC:4.1.2.5|MetaCyc:THREONINE-ALDOLASE-RXN L-threonine aldolase activity|L-threonine acetaldehyde-lyase activity|L-threonine acetaldehyde-lyase (glycine-forming) Catalysis of the reaction: L-threonine = glycine + acetaldehyde. CHEBI:63048 1,3-thiazolium cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63048 CHEBI:63047 food emulsifier biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63047 GO:0004790 thioether S-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004790 RHEA:19613|KEGG_REACTION:R02572|MetaCyc:THIOETHER-S-METHYLTRANSFERASE-RXN|EC:2.1.1.96 thioether methyltransferase activity|S-adenosyl-L-methionine:thioether S-methyltransferase activity|S-adenosyl-L-methionine:dimethyl-sulfide S-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine(1+) + dimethyl sulfide = S-adenosyl-L-homocysteine + trimethylsulfonium. CHEBI:63046 emulsifier biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_63046 CHEBI:133243 O-[S-(long-chain fatty acyl)pantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133243 CHEBI:77681 1-palmityl-2-acetyl-3-lauroyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77681 CHEBI:77680 1-palmityl-2-acetyl-3-palmitoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77680 CHEBI:133249 saturated fatty aldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133249 CHEBI:77685 1,2-dioleoyl-3-lauroyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77685 CHEBI:77684 1,2-dioleoyl-3-myristoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77684 CHEBI:77683 1,2-dioleoyl-3-linoleoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77683 CHEBI:77682 1-palmityl-2-acetyl-3-capryloyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77682 CHEBI:77689 L-mimosine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77689 CHEBI:77688 formononetin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77688 CHEBI:133242 O-[S-(medium-chain fatty acyl)pantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133242 CHEBI:77687 2'-hydroxyformononetin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77687 CHEBI:133241 omega-carboxyacyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133241 CHEBI:77686 1,2-dioleoyl-3-stearoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77686 CHEBI:28607 coproporphyrinogen I biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28607 CHEBI:28600 farnesol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28600 CHEBI:28602 beta-D-fructofuranose 2,6-bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28602 CHEBI:28609 N-benzoyl-4-methoxyanthranilic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28609 CHEBI:28616 carbamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28616 CHEBI:28618 1,4-dichlorobenzene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28618 CHEBI:28610 1-O-oleoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28610 CHEBI:28619 acrylamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28619 CARO:0000000 anatomical entity biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/CARO_0000000 CARO:0000003 connected anatomical structure biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/CARO_0000003 CARO:0000007 immaterial anatomical entity biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/CARO_0000007 CARO:0000006 material anatomical entity biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/CARO_0000006 CHEBI:77609 monoalk-1-enyl-sn-glycerol 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77609 GO:0004921 interleukin-11 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004921 IL-11R|gp130|IL-11 receptor activity Combining with interleukin-11 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0004920 interleukin-10 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004920 IL-10R|IL-10 receptor activity Combining with interleukin-10 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0004923 leukemia inhibitory factor receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004923 leukemia inhibitory factor receptor beta-protein activity|LIF receptor activity Combining with leukemia inhibitory factor (LIF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. CHEBI:28689 dehydroepiandrosterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28689 CHEBI:53647 dehydroglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53647 CHEBI:28685 molybdenum atom biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28685 CHEBI:28684 4-acetamidobutanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28684 CHEBI:28681 N,N'-diacetylchitobiose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28681 CHEBI:28680 cytarabine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28680 CHEBI:28683 kynurenine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28683 GO:0004929 obsolete frizzled-2 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004929 frizzled-2 receptor activity OBSOLETE. Combining with to a member of the Wnt-family of signaling molecules to initiate a change in cell activity. NCBITaxon:6960 Hexapoda organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_6960 Atelocerata|Tracheata|insects|insects|Uniramia GO:0004928 obsolete frizzled receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004928 frizzled receptor activity OBSOLETE. Combining with a member of the Wnt-family of signaling molecules to initiate a change in cell activity. CHEBI:53643 phyllocladan-16alpha-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_53643 GO:0004925 prolactin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004925 Combining with prolactin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0004924 oncostatin-M receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004924 Combining with oncostatin-M and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0004927 obsolete sevenless receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004927 sevenless receptor activity OBSOLETE. (Was not defined before being made obsolete). CHEBI:7466 nandrolone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_7466 CHEBI:14030 crepenynate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_14030 GO:0004926 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004926 CHEBI:38001 2,6-diaminopurines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38001 GO:0004932 mating-type factor pheromone receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004932 Combining with a mating-type factor pheromone to initiate a change in cell activity. GO:0004931 extracellularly ATP-gated cation channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004931 Reactome:R-HSA-877187 P2X receptor|purinoceptor|purinoreceptor Enables the transmembrane transfer of a cation by a channel that opens when ATP is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane. GO:0004934 mating-type alpha-factor pheromone receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004934 class D G-protein coupled receptor activity|class D G-protein-coupled receptor activity|class D G protein coupled receptor activity|class D GPCR activity Combining with the mating-type alpha-factor pheromone to initiate a change in cell activity. GO:0004933 mating-type a-factor pheromone receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004933 class D G-protein coupled receptor activity|class D G-protein-coupled receptor activity|class D G protein coupled receptor activity|class D GPCR activity Combining with the mating-type a-factor pheromone to initiate a change in cell activity. CHEBI:53634 neomycin C biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53634 CHEBI:28699 cyclic 2,3-bisphospho-D-glyceric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28699 GO:0004930 G protein-coupled receptor activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0004930 Reactome:R-HSA-114552|Wikipedia:GPCR|Reactome:R-HSA-167408|Reactome:R-HSA-114558 orphan GPCR activity|Epstein-Barr Virus-induced receptor activity|G protein linked receptor activity|orphan G-protein coupled receptor activity|G protein coupled receptor activity|Mas proto-oncogene receptor activity|super conserved receptor expressed in brain receptor activity|RDC1 receptor activity|GPCR activity|ligand-dependent GPCR activity|G-protein coupled receptor activity|G-protein coupled receptor activity, unknown ligand|G-protein linked receptor activity|orphan G protein coupled receptor activity|EBV-induced receptor|receptor activity, G-protein coupled|SREB receptor Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. CHEBI:28697 21-deoxycortisol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28697 CHEBI:28691 alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1->1')-Cer biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28691 CHEBI:28694 copper atom biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28694 CHEBI:14027 corydaline biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_14027 CHEBI:598 1-alkyl-2-acylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_598 GO:0004939 beta-adrenergic receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004939 beta adrenoceptor Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta-adrenergic receptors; the activity involves transmitting the signal to the Gs alpha subunit of a heterotrimeric G protein. GO:0004936 alpha-adrenergic receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004936 alpha adrenoceptor Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of alpha-adrenergic receptors. GO:0004935 adrenergic receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004935 Wikipedia:Adrenergic_receptor adrenoceptor activity Combining with epinephrine or norepinephrine and transmitting the signal across the membrane by activating the alpha-subunit of an associated heterotrimeric G-protein complex. GO:0004938 alpha2-adrenergic receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004938 alpha2 adrenoceptor Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of alpha2-adrenergic receptors; the activity involves transmitting the signal to the Gi alpha subunit of a heterotrimeric G protein. GO:0004937 alpha1-adrenergic receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004937 alpha1 adrenoceptor Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of alpha1-adrenergic receptors; the activity involves transmitting the signal to the Gq alpha subunit of a heterotrimeric G protein. CHEBI:38012 aminoglycoside sulfate salt biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_38012 GO:0004901 granulocyte macrophage colony-stimulating factor receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004901 GMC-SF receptor activity|granulocyte macrophage colony stimulating factor receptor activity|GM-CSF receptor activity|CSF2R|CSF-2 receptor activity Combining with granulocyte macrophage colony-stimulating factor (GM-CSF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0004900 erythropoietin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004900 Combining with erythropoietin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. CHEBI:53628 2,6-dideoxy-alpha-D-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53628 CHEBI:28666 leukotriene D4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28666 CHEBI:28663 galactitol 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28663 CHEBI:28661 gamma-linolenic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28661 CHEBI:28660 (-)-alpha-pinene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28660 GO:0004907 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004907 GO:0004906 interferon-gamma receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004906 IFN-gamma receptor activity|type II interferon receptor activity|IFNG receptor activity Combining with interferon-gamma (a type II interferon) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0004909 interleukin-1, type I, activating receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004909 interleukin-1 type I receptor activity|IL-1 type I, activating receptor|interleukin-1, type I, activating binding|interleukin-1 activating receptor activity|IL-1 type I, activating binding Combining with interleukin-1 to initiate a change in cell activity via signaling pathways and mediated by adaptor proteins. GO:0004908 interleukin-1 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004908 Wikipedia:Interleukin-1_receptor IL-1 receptor activity|IL-1R Combining with interleukin-1 to initiate a change in cell activity. Interleukin-1 is produced mainly by activated macrophages and is involved in the inflammatory response. GO:0004903 growth hormone receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004903 Combining with a growth hormone and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0004902 granulocyte colony-stimulating factor receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004902 G-CSF receptor activity|CSF3R|granulocyte colony stimulating factor receptor activity Combining with granulocyte colony-stimulating factor (G-CSF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0004905 type I interferon receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004905 interferon-delta receptor activity|interferon-alpha/beta receptor activity|interferon-kappa receptor activity|interferon-epsilon receptor activity|interferon-tau receptor activity|interferon-zeta receptor activity|type I IFN receptor activity|interferon-omega receptor activity|interferon-beta receptor activity|interferon-alpha receptor activity Combining with a type I interferon and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Type I interferons include the interferon-alpha, beta, delta, epsilon, zeta, kappa, tau, and omega gene families. GO:0004904 interferon receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004904 IFN receptor activity Combining with an interferon and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0004910 interleukin-1, type II, blocking receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004910 interleukin-1, type II, blocking binding|IL-1 type II, blocking receptor|IL-1 type II, blocking binding|interleukin-1 blocking receptor activity|interleukin-1 type II receptor activity Combining with interleukin-1 to initiate a change in cell activity by inhibiting the activity of type I interleukin receptors. GO:0004912 interleukin-3 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004912 Wikipedia:Interleukin-3_receptor IL-3R|IL-3 receptor activity Combining with interleukin-3 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0004911 interleukin-2 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004911 IL-2 receptor activity|IL-2R Combining with interleukin-2 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. CHEBI:28673 3-oxopropanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28673 CHEBI:28675 dextrin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28675 GO:0004918 interleukin-8 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004918 IL-8R|IL-8 receptor activity Combining with interleukin-8 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0004917 interleukin-7 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004917 IL-7R|IL-7 receptor activity Combining with interleukin-7 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0004919 interleukin-9 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004919 IL-9R|IL-9 receptor activity Combining with interleukin-9 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0004914 interleukin-5 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004914 IL-5R|IL-5 receptor activity Combining with interleukin-5 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0004913 interleukin-4 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004913 IL-4R|IL-4 receptor activity Combining with interleukin-4 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0004915 interleukin-6 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004915 IL-6R|gp130|IL-6 receptor activity Combining with interleukin-6 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. CHEBI:28648 beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28648 CHEBI:53604 N-acetyl-alpha-D-galactosaminyl-L-serine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_53604 CHEBI:28645 beta-D-fructofuranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28645 CHEBI:28644 2-oxopentanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28644 CHEBI:28647 3-O-methylgallic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28647 CHEBI:28646 ammeline biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28646 CHEBI:28640 lipoteichoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28640 CHEBI:53609 O-(N-acetyl-alpha-D-galactosaminyl)-L-threonine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53609 CHEBI:53608 O-(N-acetyl-alpha-D-galactosaminyl)-L-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53608 CHEBI:28659 phosphorus atom biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28659 CHEBI:28651 (S)-norlaudanosoline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28651 CHEBI:28654 3-methyl-2-oxovalerate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28654 CHEBI:28629 precorrin-8X biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28629 CHEBI:28624 tetrahydrofolyl-poly(glutamic acid) macromolecule biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28624 CHEBI:28621 triethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28621 CHEBI:7489 neamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_7489 CHEBI:28638 isobutyronitrile biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28638 CHEBI:28637 2',3'-cyclic UMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28637 CHEBI:28639 UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28639 CHEBI:28636 3-methyl-6-methoxy-2-octaprenyl-1,4-benzoquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28636 CHEBI:28635 2-isopropylmalic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28635 CHEBI:28630 3-hydroxypyridin-4(1H)-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28630 CHEBI:28632 (S)-3-hydroxyoctanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28632 CHEBI:28631 3-phenylpropionic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28631 NCBITaxon:2 Bacteria organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_2 Prokaryotae|Prokaryota|eubacteria|Monera|prokaryotes|Procaryotae|prokaryote|bacteria NCBITaxon:1 root organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_1 all GO:0004888 transmembrane signaling receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004888 Reactome:R-HSA-193672 transmembrane signalling receptor activity|transmembrane receptor activity Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction. GO:0004887 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004887 GO:0004889 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004889 GO:0004884 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004884 GO:0004883 glucocorticoid receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004883 Combining with a glucocorticoid and transmitting the signal within the cell trigger a change in cell activity or function. GO:0004886 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004886 GO:0004880 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004880 GO:0004882 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004882 CHEBI:133331 metal oxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133331 CHEBI:77575 alkyl,acyl-sn-glycerol 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77575 CHEBI:77578 monoalkyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77578 CHEBI:77576 monoalkyl-sn-glycerol 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77576 GO:0004899 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004899 GO:0004898 obsolete gp130 biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004898 gp130 OBSOLETE. (Was not defined before being made obsolete). GO:0004895 cell adhesion receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004895 The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to the external substrate or to another cell and to initiate intracellular signaling. Cell adhesion receptors include integrins and cadherins. GO:0004894 obsolete T cell receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004894 T cell receptor activity OBSOLETE. (Was not defined before being made obsolete). GO:0004897 ciliary neurotrophic factor receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004897 gp130|CNTF receptor activity Combining with ciliary neurotrophic factor (CNTF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0004896 cytokine receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004896 IL receptor|interleukin receptor activity|hematopoietin/interferon-class (D200-domain) cytokine receptor activity Combining with a cytokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0004891 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004891 GO:0004890 GABA-A receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004890 ionotropic GABA receptor activity Combining with the amino acid gamma-aminobutyric acid (GABA, 4-aminobutyrate) to initiate a change in cell activity. GABA-A receptors function as chloride channels. GO:0004892 obsolete B cell receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004892 B cell receptor activity OBSOLETE. (Was not defined before being made obsolete). CHEBI:133345 10-HETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133345 CHEBI:513 1,3,4,6-tetrachlorocyclohexa-1,4-diene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_513 CHEBI:133346 12-oxo-20-hydroxyleukotriene B4(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133346 CHEBI:77580 1-hexadecyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77580 CHEBI:77583 (2S)-2-acetamido-4-aminobutanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77583 CHEBI:77589 monoacyl-sn-glycerol 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77589 CHEBI:77587 (2S)-2-acetamido-4-aminobutanoic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77587 GO:0004866 endopeptidase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004866 endoproteinase inhibitor|proteinase inhibitor|alpha-2 macroglobulin Stops, prevents or reduces the activity of an endopeptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides. GO:0004865 protein serine/threonine phosphatase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004865 Stops, prevents or reduces the activity of a serine/threonine protein phosphatase, an enzyme that catalyzes the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate. GO:0004868 obsolete serpin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004868 serpin OBSOLETE. A superfamily of proteins, many of which inhibit serine proteinases and exhibit a high degree of homology with classical serine proteinase inhibitors such as alpha1-antitrypsin or antithrombin. GO:0004867 serine-type endopeptidase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004867 Reactome:R-HSA-158800|Reactome:R-HSA-158795|Reactome:R-HSA-158893|Reactome:R-HSA-159005|Reactome:R-HSA-159001 serine proteinase inhibitor activity|serine protease inhibitor activity|serpin activity Stops, prevents or reduces the activity of serine-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; a serine residue (and a histidine residue) are at the active center of the enzyme. GO:0004862 cAMP-dependent protein kinase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004862 Reactome:R-HSA-180073 Stops, prevents or reduces the activity of a cAMP-dependent protein kinase. GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004861 Reactome:R-HSA-187934|Reactome:R-HSA-69562 cyclin-dependent kinase inhibitor|cyclin-dependent protein kinase inhibitor activity|CDK inhibitor|cyclin dependent protein kinase inhibitor activity|cyclin dependent kinase inhibitor Stops, prevents or reduces the activity of a cyclin-dependent protein serine/threonine kinase. GO:0004864 protein phosphatase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004864 phosphoprotein phosphatase inhibitor activity|protein phosphatase type 2A inhibitor activity|protein phosphatase 2 inhibitor activity Stops, prevents or reduces the activity of a protein phosphatase, an enzyme that hydrolyzes phosphate groups from phosphorylated proteins. GO:0004863 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004863 CHEBI:133318 hydroxy fatty aldehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133318 GO:0004860 protein kinase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004860 Stops, prevents or reduces the activity of a protein kinase, an enzyme which phosphorylates a protein. CHEBI:133319 10,11-dihydro-12-oxoleukotriene B4(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133319 CHEBI:77593 2-oleoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77593 CHEBI:77592 monacyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77592 GO:0004869 cysteine-type endopeptidase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004869 thiol protease inhibitor|cysteine protease inhibitor activity|cystatin Stops, prevents or reduces the activity of a cysteine-type endopeptidase, any enzyme that hydrolyzes peptide bonds in polypeptides by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile. GO:0004877 complement component C3b receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004877 Combining with the C3b product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0004876 complement component C3a receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004876 C3a anaphylatoxin receptor activity Combining with the C3a product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0004879 nuclear receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004879 calcitriol receptor activity|vitamin A receptor activity|9-cis retinoic acid receptor activity|juvenile hormone receptor activity|ecdysteroid hormone receptor activity|nuclear receptor activity|ligand-dependent nuclear receptor activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|1,25-(OH)2D3 receptor activity|ligand-dependent transcription factor activity|estrogen nuclear receptor activity|thyroid hormone receptor activity|nuclear hormone receptor|RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding|retinoid-X receptor activity|androgen receptor activity|retinoic acid receptor activity|RXR|RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding|vitamin D3 receptor activity|RNA polymerase II transcription factor activity, glucocorticoid-activated sequence-specific DNA binding|vitamin D receptor activity|glucocorticoid receptor activity A DNA-binding transcription factor activity regulated by binding to a ligand that modulates the transcription of specific gene sets transcribed by RNA polymerase II. Nuclear receptor ligands are usually lipid-based (such as a steroid hormone) and the binding of the ligand to its receptor often occurs in the cytoplasm, which leads to its tranlocation to the nucleus. GO:0004878 complement component C5a receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004878 C5a anaphylatoxin receptor activity Combining with the C5a product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0004873 asialoglycoprotein receptor activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0004873 Receiving an asialoglycoprotein, and delivering the asialoglycoprotein into the cell via endocytosis. An asialoglycoprotein is a plasma glycoproteins from which the terminal sialic acid residue on their complex carbohydrate groups has been removed. The asialoglycoprotein receptor recognizes the terminal galactose and N-acetylgalactosamine units of the asialoglycoprotein, the receptor-ligand complex is internalized and transported to a sorting organelle where disassociation occurs before the receptor is recycled to the cell membrane. GO:0004872 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004872 GO:0004875 complement receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004875 anaphylatoxin receptor activity Combining with any component or product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0004874 obsolete aryl hydrocarbon receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004874 OBSOLETE. Combining with an aryl hydrocarbon and transmitting the signal to initiate a change in cell activity. The aryl hydrocarbon receptor is a ligand-activated transcription factor which translocates to the nucleus to activate transcription upon ligand-binding. CL:0011115 precursor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0011115 A cell that, by division or terminal differentiation, can give rise to other cell types. GO:0004871 obsolete signal transducer activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004871 hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity|quorum sensing signal generator activity|quorum sensing response regulator activity OBSOLETE. Conveys a signal across a cell to trigger a change in cell function or state. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response. GO:0004870 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004870 CL:0011111 gonadotropin releasing neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0011111 GnRH neuron|GnRH-secreting neuron Neuroendocrine cells that are born in the nasal placode during embryonic development and migrate through the nose and forebrain to the hypothalamus, where they regulate reproduction. CL:0011110 histaminergic neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0011110 Neuron that secretes histamine. GO:0004844 uracil DNA N-glycosylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004844 Reactome:R-HSA-110215|Reactome:R-HSA-110217 uracil-DNA glycosylase activity Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases in DNA that result from the deamination of cytosine or the misincorporation of dUTP opposite an adenine. GO:0004843 thiol-dependent ubiquitin-specific protease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004843 Reactome:R-HSA-5696564|Reactome:R-HSA-5688797|Reactome:R-HSA-4641236|Reactome:R-HSA-5689972|Reactome:R-HSA-6781779|Reactome:R-HSA-6783177|Reactome:R-HSA-6782106|Reactome:R-HSA-3640872|Reactome:R-HSA-9033491|Reactome:R-HSA-8875443|Reactome:R-HSA-5696872|Reactome:R-HSA-6781764|Reactome:R-HSA-6782820|Reactome:R-HSA-5653770|Reactome:R-HSA-5690152|Reactome:R-HSA-5696465|Reactome:R-HSA-9653514|Reactome:R-HSA-5690159|Reactome:R-HSA-5696947|Reactome:R-HSA-5690759|Reactome:R-HSA-5696945|Reactome:R-HSA-5696997|Reactome:R-HSA-6786171|EC:3.4.19.12|Reactome:R-HSA-6782628|Reactome:R-HSA-5696534|Reactome:R-HSA-5655466|Reactome:R-HSA-3215310|Reactome:R-HSA-5697009|Reactome:R-HSA-1358795|Reactome:R-HSA-8865182|Reactome:R-HSA-5696968|Reactome:R-HSA-8853503|Reactome:R-HSA-3215295|Reactome:R-HSA-6781814|Reactome:R-HSA-8986083|Reactome:R-HSA-5689950|Reactome:R-HSA-5688837|Reactome:R-HSA-8873946|Reactome:R-HSA-5696605|Reactome:R-HSA-6782069|Reactome:R-HSA-5696914|Reactome:R-HSA-5690196|Reactome:R-HSA-5689973|Reactome:R-HSA-2179291|Reactome:R-HSA-5690319|Reactome:R-HSA-5691381|Reactome:R-HSA-5696958|Reactome:R-HSA-8853529|Reactome:R-HSA-6807206|Reactome:R-HSA-9033478|Reactome:R-HSA-8869456|Reactome:R-HSA-8853514|Reactome:R-HSA-5696600|Reactome:R-HSA-5690080|Reactome:R-HSA-5690157|Reactome:R-HSA-5690790|Reactome:R-HSA-8853515|Reactome:R-HSA-870437|Reactome:R-HSA-8862184|Reactome:R-HSA-6781897|Reactome:R-HSA-5696960|Reactome:R-HSA-5696627|Reactome:R-HSA-6807118 deubiquitinase activity|ubiquitin-specific protease activity|UCH2|ubiquitin hydrolase activity|thiol-dependent ubiquitinyl hydrolase activity|deubiquitylase|deubiquitinating enzyme|ubiquitinyl hydrolase activity|deubiquitinase|ubiquitinyl hydrolase 1 activity|UBP|ubiquitin C-terminal hydrolase Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ubiquitin and another protein. GO:0004846 urate oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004846 UM-BBD_reactionID:r1322|RHEA:21368|EC:1.7.3.3|MetaCyc:URATE-OXIDASE-RXN uric acid oxidase activity|uricase II activity|uricase activity|urate:oxygen oxidoreductase activity Catalysis of the reaction: urate + O2 + H2O = 5-hydroxyisourate + hydrogen peroxide. GO:0004845 uracil phosphoribosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004845 MetaCyc:URACIL-PRIBOSYLTRANS-RXN|KEGG_REACTION:R00966|RHEA:13017|EC:2.4.2.9 UPRTase activity|UMP:pyrophosphate phosphoribosyltransferase activity|UMP:diphosphate phospho-alpha-D-ribosyltransferase activity|UMP pyrophosphorylase activity|UMP diphosphorylase activity|uridine 5'-phosphate pyrophosphorylase activity|uridine monophosphate pyrophosphorylase activity|uridylic pyrophosphorylase activity|uridylate pyrophosphorylase activity Catalysis of the reaction: diphosphate + UMP = 5-phospho-alpha-D-ribose 1-diphosphate + uracil. GO:0004840 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004840 GO:0004842 ubiquitin-protein transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004842 Reactome:R-HSA-8956106|Reactome:R-HSA-936986|Reactome:R-HSA-983140|Reactome:R-HSA-2737728|Reactome:R-HSA-2730904|Reactome:R-HSA-174057|Reactome:R-HSA-183084|Reactome:R-HSA-400267|Reactome:R-HSA-179417|Reactome:R-HSA-5607728|Reactome:R-HSA-173545|Reactome:R-HSA-5607725|Reactome:R-HSA-5660753|Reactome:R-HSA-5610746|Reactome:R-HSA-5610745|Reactome:R-HSA-2172172|Reactome:R-HSA-168915|Reactome:R-HSA-2213017|Reactome:R-HSA-1169402|Reactome:R-HSA-450358|Reactome:R-HSA-5610742|Reactome:R-HSA-5684250|Reactome:R-HSA-451418|Reactome:R-HSA-3134804|Reactome:R-HSA-5693108|Reactome:R-HSA-5357757|Reactome:R-HSA-1980118|Reactome:R-HSA-918224|Reactome:R-HSA-5362412|Reactome:R-HSA-5205682|Reactome:R-HSA-211734|Reactome:R-HSA-182986|Reactome:R-HSA-174104|Reactome:R-HSA-1980074|Reactome:R-HSA-174144|Reactome:R-HSA-5483238|Reactome:R-HSA-9013974|Reactome:R-HSA-1358790|Reactome:R-HSA-975147|Reactome:R-HSA-9628444|Reactome:R-HSA-5655170|Reactome:R-HSA-5667107|Reactome:R-HSA-264444|Reactome:R-HSA-5652009|Reactome:R-HSA-183051|Reactome:R-HSA-1852623|Reactome:R-HSA-2769007|Reactome:R-HSA-870449|Reactome:R-HSA-3797226|Reactome:R-HSA-3249386|Reactome:R-HSA-2179276|Reactome:R-HSA-183036|Reactome:R-HSA-741386|Reactome:R-HSA-446877|Reactome:R-HSA-202534|Reactome:R-HSA-1169394|Reactome:R-HSA-8948709|Reactome:R-HSA-3781009|Reactome:R-HSA-3788724|Reactome:R-HSA-4332236|Reactome:R-HSA-5668534|KEGG_REACTION:R03876|Reactome:R-HSA-173542|Reactome:R-HSA-2186785|Reactome:R-HSA-174159|Reactome:R-HSA-3000335|Reactome:R-HSA-936412|Reactome:R-HSA-9645414|Reactome:R-HSA-1918095|Reactome:R-HSA-5667111|Reactome:R-HSA-180597|Reactome:R-HSA-1977296|Reactome:R-HSA-1234172|Reactome:R-HSA-1912357|Reactome:R-HSA-1169397|Reactome:R-HSA-2186747|Reactome:R-HSA-174227|Reactome:R-HSA-3134946|Reactome:R-HSA-75824|Reactome:R-HSA-1169395|Reactome:R-HSA-174195|Reactome:R-HSA-5675470|Reactome:R-HSA-983153|Reactome:R-HSA-209063|Reactome:R-HSA-205118|Reactome:R-HSA-69598|Reactome:R-HSA-983156|Reactome:R-HSA-936942|Reactome:R-HSA-202453|Reactome:R-HSA-1918092|Reactome:R-HSA-1912386|Reactome:R-HSA-2169050|Reactome:R-HSA-2187368|Reactome:R-HSA-1169406|Reactome:R-HSA-3780995|Reactome:R-HSA-183089|Reactome:R-HSA-2682349|Reactome:R-HSA-5691108|Reactome:R-HSA-1234163|Reactome:R-HSA-9701000|Reactome:R-HSA-1358792|Reactome:R-HSA-975118|Reactome:R-HSA-5607756|Reactome:R-HSA-1358789|Reactome:R-HSA-180540|Reactome:R-HSA-9645394|Reactome:R-HSA-182993|Reactome:R-HSA-1169398|Reactome:R-HSA-1363331|Reactome:R-HSA-5668454|Reactome:R-HSA-2900765|Reactome:R-HSA-9013069|Reactome:R-HSA-1169405|Reactome:R-HSA-9688831|Reactome:R-HSA-201425|Reactome:R-HSA-5607757|Reactome:R-HSA-9014342|Reactome:R-HSA-1253282|Reactome:R-HSA-187575 ubiquitin protein ligase activity|ubiquitin ligase activity|ubiquitin conjugating enzyme activity|anaphase-promoting complex activity|ubiquitin protein-ligase activity|ubiquitin-conjugating enzyme activity|E3|E2 Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages. GO:0004841 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004841 CL:0011103 sympathetic neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0011103 Sympathetic neurons are part of the sympathetic nervous system and are primarily adrenergic producing the neurotransmitter noradrenalin along with other neuropeptides. CL:0011101 chorionic trophoblast cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0011101 Cells of the uterine chorion that acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer. CL:0011109 hypocretin-secreting neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0011109 orexin A neuron that releases hypocretin as a neurotransmitter. CL:0011108 colon epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0011108 colonic epithelial cell Epithelial cell that is part of the colon epithelium. GO:0004848 ureidoglycolate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004848 EC:3.5.3.19|KEGG_REACTION:R00469|RHEA:19809|MetaCyc:UREIDOGLYCOLATE-HYDROLASE-RXN (S)-ureidoglycolate amidohydrolase (decarboxylating) Catalysis of the reaction: (S)-ureidoglycolate + H(2)O + 2 H(+) = CO(2) + glyoxylate + 2 NH(4)(+). GO:0004847 urea carboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004847 RHEA:20896|KEGG_REACTION:R00774|EC:6.3.4.6|MetaCyc:UREA-CARBOXYLASE-RXN urea carboxylase (hydrolyzing) activity|urease (ATP-hydrolysing)|urea:carbon-dioxide ligase (ADP-forming)|UCA activity|UALase activity|urea amidolyase activity|urease (ATP-hydrolyzing) activity|ATP--urea amidolyase activity|urea carboxylase (hydrolysing) Catalysis of the reaction: ATP + bicarbonate + urea = ADP + 2 H(+) + phosphate + urea-1-carboxylate. GO:0004849 uridine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004849 MetaCyc:URIDINEKIN-RXN|Reactome:R-HSA-8954327|EC:2.7.1.48|RHEA:16825 ATP:uridine 5'-phosphotransferase activity|uridine-cytidine kinase activity|uridine kinase reaction|uridine monophosphokinase activity|pyrimidine ribonucleoside kinase activity|uridine phosphokinase activity|uridine kinase (phosphorylating) Catalysis of the reaction: ATP + uridine = ADP + UMP. GO:0004855 xanthine oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004855 RHEA:21132|EC:1.17.3.2|MetaCyc:XANTHINE-OXIDASE-RXN|Reactome:R-HSA-74247|UM-BBD_enzymeID:e0781|Reactome:R-HSA-74258 xanthine:xanthine oxidase activity|Schardinger enzyme activity|xanthine:O(2) oxidoreductase activity|xanthine oxidoreductase activity|hypoxanthine-xanthine oxidase activity|xanthine:O2 oxidoreductase activity|xanthine:oxygen oxidoreductase activity|schardinger enzyme Catalysis of the reaction: xanthine + H2O + O2 = urate + hydrogen peroxide. GO:0004854 xanthine dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004854 RHEA:16669|EC:1.17.1.4|MetaCyc:RXN0-901 xanthine:NAD+ oxidoreductase activity|xanthine-NAD oxidoreductase activity|xanthine/NAD+ oxidoreductase activity|xanthine oxidoreductase activity|NAD-xanthine dehydrogenase activity|xanthine/NAD(+) oxidoreductase activity Catalysis of the reaction: xanthine + NAD+ + H2O = urate + NADH + H+. GO:0004857 enzyme inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004857 metalloenzyme inhibitor activity Binds to and stops, prevents or reduces the activity of an enzyme. GO:0004856 xylulokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004856 MetaCyc:XYLULOKIN-RXN|Reactome:R-HSA-5662466|KEGG_REACTION:R01639|EC:2.7.1.17|RHEA:10964 ATP:D-xylulose 5-phosphotransferase activity|xylulose kinase activity|xylulokinase (phosphorylating)|D-xylulokinase activity Catalysis of the reaction: D-xylulose + ATP = D-xylulose 5-phosphate + ADP + 2 H(+). GO:0004851 uroporphyrin-III C-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004851 MetaCyc:UROPORIIIMETHYLTRANSA-RXN|EC:2.1.1.107|RHEA:32459 SirA|S-adenosyl-L-methionine-dependent uroporphyrinogen III methylase activity|adenosylmethionine-uroporphyrinogen III methyltransferase activity|uroporphyrinogen-III C-methyltransferase activity|uroporphyrinogen III methylase activity|S-adenosyl-L-methionine:uroporphyrin-III C-methyltransferase activity|S-adenosyl-L-methionine:uroporphyrinogen-III C-methyltransferase activity|urogen III methylase activity|uroporphyrinogen-III methyltransferase activity|uroporphyrinogen methyltransferase activity|CobA|CysG|uroporphyrinogen-III methylase activity|SUMT activity Catalysis of the reaction: 2 S-adenosyl-L-methionine + uroporphyrin III = 2 S-adenosyl-L-homocysteine + precorrin-2. GO:0004850 uridine phosphorylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004850 RHEA:24388|MetaCyc:URPHOS-RXN|EC:2.4.2.3|Reactome:R-HSA-74372|Reactome:R-HSA-74376 uridine:phosphate alpha-D-ribosyltransferase activity|UPase activity|UPH|pyrimidine phosphorylase activity|UrdPase activity Catalysis of the reaction: uridine + phosphate = uracil + alpha-D-ribose 1-phosphate. GO:0004853 uroporphyrinogen decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004853 RHEA:19865|MetaCyc:UROGENDECARBOX-RXN|Reactome:R-HSA-190182|Reactome:R-HSA-189425|EC:4.1.1.37 porphyrinogen carboxy-lyase activity|uroporphyrinogen III decarboxylase activity|uroporphyrinogen-III carboxy-lyase activity|porphyrinogen decarboxylase activity|uroporphyrinogen-III carboxy-lyase (coproporphyrinogen-III-forming) Catalysis of the reaction: uroporphyrinogen-III = coproporphyrinogen + 4 CO2. GO:0004852 uroporphyrinogen-III synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004852 MetaCyc:UROGENIIISYN-RXN|Reactome:R-HSA-189488|RHEA:18965|KEGG_REACTION:R03165|EC:4.2.1.75 uroporphyrinogen III cosynthase activity|hydroxymethylbilane hydro-lyase (cyclizing) activity|porphobilinogenase activity|hydroxymethylbilane hydro-lyase (cyclizing; uroporphyrinogen-III-forming)|uroporphyrinogen-III cosynthase activity|URO-synthase activity|uroporphyrinogen isomerase activity|uroporphyrinogen-III cosynthetase activity Catalysis of the reaction: hydroxymethylbilane = H(2)O + uroporphyrinogen III. CHEBI:133309 12-dehydro-leukotriene B4(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133309 CHEBI:133301 O-{S-[19-(4-hydroxyphenyl)nonadecanoyl]pantetheine-4'-phosphoryl}serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133301 CHEBI:133300 O-{S-[17-(4-hydroxyphenyl)heptadecanoyl]pantetheine-4'-phosphoryl}serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133300 CHEBI:133304 S-anthraniloyl-L-cysteine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133304 GO:0004859 phospholipase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004859 Stops, prevents or reduces the activity of a phospholipase, an enzyme that catalyzes of the hydrolysis of a phospholipid. GO:0004858 dUTP pyrophosphatase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004858 Stops, prevents or reduces the activity of dUTP pyrophosphatase. GO:0004822 isoleucine-tRNA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004822 MetaCyc:ISOLEUCINE--TRNA-LIGASE-RXN|Reactome:R-HSA-380176|KEGG_REACTION:R03656|Reactome:R-HSA-379893|EC:6.1.1.5|RHEA:11060 L-isoleucine:tRNAIle ligase (AMP-forming)|isoleucine-tRNA synthetase activity|isoleucyl-transfer ribonucleate synthetase activity|isoleucine-transfer RNA ligase activity|isoleucine translase activity|isoleucyl-transfer RNA synthetase activity|isoleucyl-tRNA synthetase activity Catalysis of the reaction: L-isoleucine + ATP + tRNA(Ile) = L-isoleucyl-tRNA(Ile) + AMP + diphosphate + 2 H(+). GO:0004821 histidine-tRNA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004821 Reactome:R-HSA-380234|Reactome:R-HSA-379844|MetaCyc:HISTIDINE--TRNA-LIGASE-RXN|EC:6.1.1.21|RHEA:17313 histidyl-transfer ribonucleate synthetase activity|histidine translase activity|L-histidine:tRNAHis ligase (AMP-forming)|histidyl-tRNA synthetase activity Catalysis of the reaction: ATP + L-histidine + tRNA(His) = AMP + diphosphate + L-histidyl-tRNA(His). GO:0004824 lysine-tRNA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004824 Reactome:R-HSA-380008|Reactome:R-HSA-380233|MetaCyc:LYSINE--TRNA-LIGASE-RXN|RHEA:20792|EC:6.1.1.6 L-lysine:tRNALys ligase (AMP-forming)|lysine-tRNA synthetase activity|lysyl-transfer RNA synthetase activity|lysyl-transfer ribonucleate synthetase activity|L-lysine-transfer RNA ligase activity|lysyl-tRNA synthetase activity|lysine translase activity Catalysis of the reaction: ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys). GO:0004823 leucine-tRNA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004823 Reactome:R-HSA-380200|Reactome:R-HSA-379974|MetaCyc:LEUCINE--TRNA-LIGASE-RXN|KEGG_REACTION:R03657|RHEA:11688|EC:6.1.1.4 L-leucine:tRNALeu ligase (AMP-forming)|leucyl-transfer ribonucleic acid synthetase activity|leucine-tRNA synthetase activity|leucyl-transfer ribonucleate synthetase activity|leucyl-transfer RNA synthetase activity|leucine translase activity|leucyl-tRNA synthetase activity Catalysis of the reaction: L-leucine + ATP + tRNA(Leu) = AMP + diphosphate + 2 H(+) + Leu-tRNA(Leu). GO:0004820 glycine-tRNA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004820 Reactome:R-HSA-380240|EC:6.1.1.14|RHEA:16013|Reactome:R-HSA-380048|MetaCyc:GLYCINE--TRNA-LIGASE-RXN glycine:tRNAGly ligase (AMP-forming) activity|glycyl-transfer ribonucleic acid synthetase activity|glycyl-transfer RNA synthetase activity|glycyl translase activity|glycyl-transfer ribonucleate synthetase activity|glycyl-tRNA synthetase activity Catalysis of the reaction: ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). CHEBI:28586 verbascose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28586 CHEBI:28585 4-carboxy-4'-sulfoazobenzene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28585 CHEBI:28587 D-threose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28587 CHEBI:28581 UDP-N-acetyl-D-mannosaminouronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28581 CHEBI:28591 guaiacol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28591 GO:0004829 threonine-tRNA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004829 Reactome:R-HSA-380201|Reactome:R-HSA-380002|MetaCyc:THREONINE--TRNA-LIGASE-RXN|RHEA:24624|EC:6.1.1.3 threonyl-transfer ribonucleic acid synthetase activity|L-threonine:tRNAThr ligase (AMP-forming)|TRS|threonyl-transfer RNA synthetase activity|threonyl ribonucleic synthetase activity|threonine-transfer ribonucleate synthetase activity|threonyl-transfer ribonucleate synthetase activity|threonine translase activity|threonyl-tRNA synthetase activity Catalysis of the reaction: ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + L-threonyl-tRNA(Thr). GO:0004826 phenylalanine-tRNA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004826 MetaCyc:PHENYLALANINE--TRNA-LIGASE-RXN|Reactome:R-HSA-380203|Reactome:R-HSA-379848|EC:6.1.1.20|RHEA:19413 L-phenylalanine:tRNAPhe ligase (AMP-forming) activity|phenylalanine-tRNA synthetase activity|phenylalanyl-transfer ribonucleate synthetase activity|phenylalanine translase activity|phenylalanyl-transfer RNA synthetase activity|phenylalanyl-tRNA ligase activity|L-phenylalanyl-tRNA synthetase activity|phenylalanyl-tRNA synthetase activity|phenylalanyl-transfer RNA ligase activity Catalysis of the reaction: ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe). GO:0004825 methionine-tRNA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004825 EC:6.1.1.10|Reactome:R-HSA-380157|MetaCyc:METHIONINE--TRNA-LIGASE-RXN|Reactome:R-HSA-379994|RHEA:13481 methionyl-transfer ribonucleate synthetase activity|methionine translase activity|methionyl-tRNA synthetase activity|methionyl-transfer RNA synthetase activity|MetRS activity|methionyl-transfer ribonucleic acid synthetase activity|L-methionine:tRNAMet ligase (AMP-forming) Catalysis of the reaction: ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met). GO:0004828 serine-tRNA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004828 RHEA:12292|Reactome:R-HSA-379992|EC:6.1.1.11|MetaCyc:SERINE--TRNA-LIGASE-RXN|Reactome:R-HSA-380239 seryl-transfer ribonucleate synthetase activity|serine translase activity|seryl-transfer ribonucleic acid synthetase activity|seryl-tRNA synthetase activity|seryl-transfer RNA synthetase activity|L-serine:tRNASer ligase (AMP-forming)|SerRS activity Catalysis of the reaction: ATP + L-serine + tRNA(Ser) = AMP + diphosphate + L-seryl-tRNA(Ser). GO:0004827 proline-tRNA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004827 Reactome:R-HSA-380198|Reactome:R-HSA-379865|EC:6.1.1.15|MetaCyc:PROLINE--TRNA-LIGASE-RXN|RHEA:14305 prolyl-transferRNA synthetase activity|L-proline:tRNAPro ligase (AMP-forming)|prolyl-transfer ribonucleate synthetase activity|proline translase activity|prolyl-tRNA synthetase activity|prolyl-s-RNA synthetase activity|prolyl-transfer ribonucleic acid synthetase activity|prolinyl-tRNA ligase activity Catalysis of the reaction: ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro). GO:0004833 tryptophan 2,3-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004833 RHEA:24536|MetaCyc:TRYPTOPHAN-23-DIOXYGENASE-RXN|Reactome:R-HSA-71188|Reactome:R-HSA-198563|Reactome:R-HSA-888614|EC:1.13.11.11 TDO|L-tryptophan 2,3-dioxygenase activity|indolamine 2,3-dioxygenase activity|tryptophan peroxidase activity|L-tryptophan pyrrolase activity|tryptophan pyrrolase activity|indoleamine-pyrrole 2,3-dioxygenase activity|tryptamin 2,3-dioxygenase activity|L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing)|tryptophan oxygenase activity|tryptamine 2,3-dioxygenase activity Catalysis of the reaction: L-tryptophan + O2 = N-formyl-L-kynurenine. GO:0004832 valine-tRNA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004832 MetaCyc:VALINE--TRNA-LIGASE-RXN|KEGG_REACTION:R03665|EC:6.1.1.9|Reactome:R-HSA-380199|Reactome:R-HSA-380042|RHEA:10704 valyl-tRNA synthetase activity|L-valine:tRNAVal ligase (AMP-forming)|valyl-transfer ribonucleate synthetase activity|valine translase activity|valine transfer ribonucleate ligase activity|valyl-transfer ribonucleic acid synthetase activity|valyl-transfer RNA synthetase activity Catalysis of the reaction: L-valine + ATP + tRNA(Val) = L-valyl-tRNA(Val) + AMP + diphosphate + 2 H(+). GO:0004835 tubulin-tyrosine ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004835 EC:6.3.2.25|RHEA:17605|Reactome:R-HSA-8955706|MetaCyc:6.3.2.25-RXN tubulinyl-tyrosine ligase activity|TTL activity|alpha-tubulin:L-tyrosine ligase (ADP-forming) Catalysis of the reaction: ATP + detyrosinated alpha-tubulin + L-tyrosine = alpha-tubulin + ADP + phosphate. GO:0004834 tryptophan synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004834 KEGG_REACTION:R02722|EC:4.2.1.20|RHEA:10532|MetaCyc:TRYPSYN-RXN indoleglycerol phosphate aldolase activity|L-serine hydro-lyase [adding 1-C-(indol-3-yl)glycerol 3-phosphate; L-tryptophan and glyceraldehyde-3-phosphate-forming]|L-serine hydro-lyase (adding indoleglycerol-phosphate)|tryptophan desmolase activity|L-tryptophan synthetase activity|tryptophan synthetase activity Catalysis of the reaction: L-serine + (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = L-tryptophan + glyceraldehyde 3-phosphate + H2O. GO:0004831 tyrosine-tRNA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004831 RHEA:10220|EC:6.1.1.1|MetaCyc:TYROSINE--TRNA-LIGASE-RXN|Reactome:R-HSA-380170|KEGG_REACTION:R02918|Reactome:R-HSA-379980 L-tyrosine-tRNATyr ligase (AMP-forming)|tyrosyl-transfer ribonucleic acid synthetase activity|L-tyrosine-tRNA(Tyr) ligase (AMP-forming) activity|tyrosyl-transfer RNA synthetase activity|tyrosyl-tRNA ligase activity|tyrosine-transfer ribonucleate synthetase activity|tyrosyl-tRNA synthetase activity|tyrosyl-transfer ribonucleate synthetase activity|tyrosine-transfer RNA ligase activity|L-tyrosine:tRNATyr ligase (AMP-forming)|tyrosine translase activity|tyrosine tRNA synthetase activity Catalysis of the reaction: L-tyrosine + ATP + tRNA(Tyr) = L-tyrosyl-tRNA(Tyr) + AMP + diphosphate + 2 H(+). GO:0004830 tryptophan-tRNA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004830 Reactome:R-HSA-380222|EC:6.1.1.2|Reactome:R-HSA-379977|RHEA:24080|MetaCyc:TRYPTOPHAN--TRNA-LIGASE-RXN tryptophanyl-transfer ribonucleic synthetase activity|L-tryptophan-tRNA(Trp) ligase (AMP-forming) activity|tryptophanyl-transfer RNA synthetase activity|TrpRS activity|L-tryptophan-tRNATrp ligase (AMP-forming)|tryptophanyl ribonucleic synthetase activity|tryptophanyl-transfer ribonucleate synthetase activity|tryptophanyl-tRNA synthetase activity|tryptophanyl-tRNA synthase activity|tryptophan translase activity|tryptophanyl-transfer ribonucleic acid synthetase activity|L-tryptophan:tRNATrp ligase (AMP-forming) Catalysis of the reaction: ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophanyl-tRNA(Trp). CHEBI:28599 siroheme biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28599 CHEBI:28592 ricinoleic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28592 GO:0004837 tyrosine decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004837 RHEA:14345|MetaCyc:TYROSINE-DECARBOXYLASE-RXN|EC:4.1.1.25 L-tyrosine decarboxylase activity|L-tyrosine carboxy-lyase activity|L-(-)-tyrosine apodecarboxylase activity|L-tyrosine carboxy-lyase (tyramine-forming) Catalysis of the reaction: L-tyrosine = tyramine + CO2. GO:0004836 tyramine-beta hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004836 Catalysis of the hydroxylation of tyramine to form octopamine. GO:0004839 ubiquitin activating enzyme activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004839 EC:6.2.1.45|Reactome:R-HSA-8865090|Reactome:R-HSA-8852132|Reactome:R-HSA-8865050|Reactome:R-HSA-8852134|Reactome:R-HSA-8852133|Reactome:R-HSA-8865098 E1 ubiquitin-activating enzyme Catalysis of the reaction: E1 + ubiquitin + ATP--> E1-ubiquitin + AMP + PPi, where the E1-ubiquitin linkage is a thioester bond between the C-terminal glycine of Ub and a sulfhydryl side group of an E1 cysteine residue. This is the first step in a cascade of reactions in which ubiquitin is ultimately added to a protein substrate. GO:0004838 L-tyrosine:2-oxoglutarate aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004838 MetaCyc:TYROSINE-AMINOTRANSFERASE-RXN|Reactome:R-HSA-517444|EC:2.6.1.5|RHEA:15093|Reactome:R-HSA-71155 L-tyrosine aminotransferase activity|tyrosine-2-ketoglutarate aminotransferase activity|tyrosine-alpha-ketoglutarate transaminase activity|phenylalanine transaminase activity|tyrosine aminotransferase activity|L-phenylalanine 2-oxoglutarate aminotransferase activity|phenylpyruvic acid transaminase activity|glutamic phenylpyruvic aminotransferase activity|tyrosine transaminase activity|tyrosine-alpha-ketoglutarate aminotransferase activity|phenylalanine aminotransferase activity|glutamic-hydroxyphenylpyruvic transaminase activity|phenylalanine-alpha-ketoglutarate transaminase activity|phenylpyruvate transaminase activity|TyrAT activity Catalysis of the reaction: L-tyrosine + 2-oxoglutarate = 4-hydroxyphenylpyruvate + L-glutamate. CHEBI:77506 1-pentadecene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77506 CHEBI:77503 (23Z,26Z,29Z,32Z,35Z)-octatriacontapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77503 CHEBI:77500 (18Z,21Z,24Z,27Z,30Z,33Z)-hexatriacontahexaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77500 CHEBI:133398 L-methionyl-L-alanyl(1+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133398 CHEBI:133399 N-acetyl-L-methionyl-L-alanyl residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133399 CHEBI:133392 prostaglandin C2(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133392 CHEBI:133391 prostaglandin B2(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133391 CHEBI:133393 prostaglandin B1(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133393 CHEBI:133396 prostaglandin J2(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133396 CHEBI:77528 (11Z,14Z,17Z,20Z)-hexacosatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77528 CHEBI:77527 (6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77527 CHEBI:77526 (9Z,12Z,15Z,18Z)-tetracosatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77526 CHEBI:77525 (17Z)-hexacosenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77525 CHEBI:77524 hexadecadienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77524 CHEBI:77523 Maillard reaction product biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77523 CHEBI:77522 (9Z,12Z)-hexadecadienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77522 CHEBI:77521 thermal degradation product biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77521 CHEBI:77539 (23Z,26Z,29Z,32Z)-octatriacontatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77539 CHEBI:77538 (21Z,24Z,27Z,30Z)-hexatriacontatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77538 CHEBI:77537 trans-9-octadecenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77537 CHEBI:77536 (19Z,22Z,25Z,28Z)-tetratriacontatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77536 CHEBI:133375 N-acetyl-L-threonyl residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133375 CHEBI:133378 N-acetyl-L-methionyl-L-leucyl residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133378 CHEBI:133377 L-methionyl-L-leucyl(1+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133377 CHEBI:133379 N-acetyl-L-methionyl-L-isoleucyl residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133379 CHEBI:133370 prostaglandin A2(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133370 CHEBI:133372 N-acetyl-L-cysteinyl residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133372 CHEBI:77535 (17Z,20Z,23Z,26Z)-dotriacontatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77535 CHEBI:133371 N-acetyl-L-valyl residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133371 CHEBI:77534 (15Z,18Z,21Z,24Z)-triacontatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77534 CHEBI:133374 13,14-dihydro-15-keto-PGF2alpha(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133374 CHEBI:77532 (13Z,16Z,19Z,22Z)-octacosatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77532 CHEBI:77549 (2E,9Z)-hexadecadienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77549 CHEBI:77548 trans-2-undecenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77548 CHEBI:77547 undecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77547 GO:0038203 TORC2 signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038203 TORC2 signal transduction A series of intracellular molecular signals mediated by TORC2; TOR (rapamycin-insensitive companion of TOR) in complex with at least Rictor (regulatory-associated protein of TOR), or orthologs of, and other signaling components. CHEBI:133387 L-methionyl-L-tryptophyl(1+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133387 GO:0038202 TORC1 signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0038202 TORC1 signal transduction A series of intracellular molecular signals mediated by TORC1; TOR (target of rapamycin) in complex with at least Raptor (regulatory-associated protein of TOR), or orthologs of, and other signaling components. CHEBI:133386 N-acetyl-L-methionyl-L-tryptophyl residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133386 CHEBI:133381 9,10-epoxy-18-hydroxyoctadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133381 CHEBI:133380 L-methionyl-L-isoleucyl(1+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133380 CHEBI:133383 L-methionyl-L-phenylalanyl(1+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133383 CHEBI:77545 trans-2-pentadecenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77545 CHEBI:133382 N-acetyl-L-methionyl-L-phenylalanyl residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133382 GO:0038201 TOR complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0038201 target of rapamycin complex|mTOR complex|TOR signaling complex A protein complex that contains at least TOR (target of rapamycin) in complex with other signaling components. Mediates the phosphorylation and activation of downstream signaling components including PKB (AKT) or S6K. CHEBI:133385 L-methionyl-L-tyrosyl(1+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133385 GO:0038200 ethylene receptor histidine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0038200 Combining with ethylene and transmitting the signal within the cell to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-histidine = ADP + a protein-L-histidine phosphate. CHEBI:133384 N-acetyl-L-methionyl-L-tyrosyl residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133384 CHEBI:77559 (2E,4Z,7Z,10Z,13Z,16Z,19Z)-docosaheptaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77559 CHEBI:77558 (2E,9Z,12Z)-octadecatrienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77558 CHEBI:133356 L-methionyl-L-asparaginyl(1+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133356 CHEBI:133358 N(alpha)-acetyl-L-methionyl-L-asparaginyl residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133358 CHEBI:133359 L-methionyl-L-glutamyl zwitterionic residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133359 CHEBI:77553 (2E,9Z)-octadecadienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77553 CHEBI:77552 (2E,9E)-octadecadienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77552 CHEBI:77551 trans-2-heptadecenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77551 CHEBI:77550 (2R)-pristanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77550 CHEBI:77557 (2S)-2-methylpentadecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77557 CHEBI:133351 N-carbamoylglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133351 CHEBI:133367 resolvin D2(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133367 CHEBI:133369 N-acetylglycyl residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133369 CHEBI:77560 1,1'-dioleyl 2,2'-dilysocardiolipin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77560 CHEBI:77561 trioleoyl 2-monolysocardiolipin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77561 CHEBI:133361 L-methionyl-L-glutaminyl(1+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133361 CHEBI:133360 N(alpha)-acetyl-L-methionyl-L-glutamyl(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133360 CHEBI:133362 N-acetyl-L-methionyl-L-glutaminyl residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133362 GO:1903189 glyoxal metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903189 glyoxal metabolism The chemical reactions and pathways involving glyoxal. GO:1903199 negative regulation of L-dopa decarboxylase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903199 negative regulation of DOPA decarboxylase activity|down-regulation of DOPA decarboxylase activity|down-regulation of L-dopa decarboxylase activity|down-regulation of DDC activity|down-regulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity|negative regulation of DDC activity|negative regulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity|inhibition of DOPA decarboxylase activity|inhibition of L-dopa decarboxylase activity|inhibition of 4-dihydroxyl-L-phenylalanine decarboxylase activity|downregulation of DDC activity|down regulation of DDC activity|inhibition of DDC activity|down regulation of DOPA decarboxylase activity|down regulation of L-dopa decarboxylase activity|down regulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity|downregulation of DOPA decarboxylase activity|downregulation of L-dopa decarboxylase activity|downregulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity Any process that stops, prevents or reduces the frequency, rate or extent of L-dopa decarboxylase activity. GO:1903198 regulation of L-dopa decarboxylase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903198 regulation of DDC activity|regulation of DOPA decarboxylase activity|regulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity Any process that modulates the frequency, rate or extent of L-dopa decarboxylase activity. GO:1903197 positive regulation of L-dopa biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903197 positive regulation of L-dopa anabolism|up regulation of L-dopa anabolism|positive regulation of L-dopa synthesis|up-regulation of L-dopa biosynthetic process|up-regulation of L-dopa biosynthesis|up regulation of L-dopa synthesis|positive regulation of L-dopa formation|up regulation of L-dopa formation|upregulation of L-dopa anabolism|upregulation of L-dopa biosynthetic process|upregulation of L-dopa biosynthesis|upregulation of L-dopa synthesis|upregulation of L-dopa formation|up-regulation of L-dopa anabolism|activation of L-dopa anabolism|up regulation of L-dopa biosynthesis|up regulation of L-dopa biosynthetic process|activation of L-dopa biosynthesis|up-regulation of L-dopa synthesis|activation of L-dopa biosynthetic process|activation of L-dopa synthesis|positive regulation of L-dopa biosynthesis|up-regulation of L-dopa formation|activation of L-dopa formation Any process that activates or increases the frequency, rate or extent of L-dopa biosynthetic process. GO:1903196 negative regulation of L-dopa biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903196 negative regulation of L-dopa synthesis|down-regulation of L-dopa synthesis|negative regulation of L-dopa formation|down-regulation of L-dopa formation|downregulation of L-dopa anabolism|inhibition of L-dopa biosynthetic process|inhibition of L-dopa biosynthesis|downregulation of L-dopa synthesis|down regulation of L-dopa anabolism|inhibition of L-dopa anabolism|downregulation of L-dopa formation|down regulation of L-dopa synthesis|inhibition of L-dopa synthesis|down regulation of L-dopa formation|down regulation of L-dopa biosynthetic process|down regulation of L-dopa biosynthesis|inhibition of L-dopa formation|downregulation of L-dopa biosynthetic process|downregulation of L-dopa biosynthesis|negative regulation of L-dopa anabolism|down-regulation of L-dopa anabolism|negative regulation of L-dopa biosynthesis|down-regulation of L-dopa biosynthesis|down-regulation of L-dopa biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of L-dopa biosynthetic process. GO:1903195 regulation of L-dopa biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903195 regulation of L-dopa anabolism|regulation of L-dopa synthesis|regulation of L-dopa formation|regulation of L-dopa biosynthesis Any process that modulates the frequency, rate or extent of L-dopa biosynthetic process. GO:1903193 sesquarterpene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903193 sesquarterpene synthesis|sesquarterpene formation|sesquarterpene biosynthesis|sesquarterpene anabolism The chemical reactions and pathways resulting in the formation of sesquarterpene. GO:1903192 sesquarterpene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903192 sesquarterpene metabolism The chemical reactions and pathways involving sesquarterpene. GO:1903191 glyoxal biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903191 glyoxal biosynthesis|glyoxal anabolism|glyoxal synthesis|glyoxal formation The chemical reactions and pathways resulting in the formation of glyoxal. GO:1903190 glyoxal catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903190 glyoxal breakdown|glyoxal catabolism|glyoxal degradation The chemical reactions and pathways resulting in the breakdown of glyoxal. UBERON:0035764 pulmonary lymph node biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035764 intrapulmonary lymph node|pulmonary node UBERON:0035763 cavity of cardiac chamber biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035763 cardiac chamber cavity|heart lumen|heart cavity UBERON:0035767 intrapulmonary bronchus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035767 UBERON:0035784 seminal clot biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035784 seminal coagulum A portion of semen in a coagulated state. CHEBI:691622 1,3,7-trimethyluric acid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_691622 GO:1903109 positive regulation of mitochondrial transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903109 upregulation of mitochondrial transcription|up-regulation of transcription from mitochondrial promoter|up regulation of mitochondrial transcription|activation of mitochondrial transcription|positive regulation of transcription from mitochondrial promoter|positive regulation of mitochondrial transcription|upregulation of transcription from mitochondrial promoter|up-regulation of mitochondrial transcription|up regulation of transcription from mitochondrial promoter|activation of transcription from mitochondrial promoter Any process that activates or increases the frequency, rate or extent of transcription occuring in the mitochondrion. GO:1903108 regulation of mitochondrial transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903108 regulation of transcription from mitochondrial promoter|regulation of mitochondrial transcription Any process that modulates the frequency, rate or extent of transcription occuring in the mitochondrion. GO:1903107 insulin receptor signaling pathway involved in dauer larval development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903107 daf-2 receptor signaling pathway involved in dauer larval development|insulin receptor signalling pathway involved in dauer larval development Any insulin receptor signaling pathway that is involved in dauer larval development. CHEBI:28563 beta-D-mannose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28563 GO:1903106 positive regulation of insulin receptor signaling pathway involved in determination of adult lifespan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903106 activation of insulin receptor signaling pathway involved in determination of adult lifespan|upregulation of insulin receptor signaling pathway of determination of adult lifespan|up regulation of daf-2 receptor signaling pathway of determination of adult lifespan|positive regulation of daf-2 receptor signaling pathway of determination of adult lifespan|upregulation of insulin receptor signalling pathway of determination of adult lifespan|up regulation of insulin receptor signaling pathway involved in determination of adult lifespan|activation of daf-2 receptor signaling pathway of determination of adult lifespan|up regulation of insulin receptor signaling pathway of determination of adult lifespan|activation of insulin receptor signaling pathway of determination of adult lifespan|positive regulation of insulin receptor signaling pathway of determination of adult lifespan|up-regulation of insulin receptor signalling pathway of determination of adult lifespan|activation of insulin receptor signalling pathway of determination of adult lifespan|up-regulation of daf-2 receptor signaling pathway of determination of adult lifespan|upregulation of insulin receptor signaling pathway involved in determination of adult lifespan|upregulation of daf-2 receptor signaling pathway of determination of adult lifespan|up-regulation of insulin receptor signaling pathway of determination of adult lifespan|positive regulation of insulin receptor signalling pathway of determination of adult lifespan|up regulation of insulin receptor signalling pathway of determination of adult lifespan|up-regulation of insulin receptor signaling pathway involved in determination of adult lifespan Any process that activates or increases the frequency, rate or extent of insulin receptor signaling pathway involved in determination of adult lifespan. GO:1903105 negative regulation of insulin receptor signaling pathway involved in determination of adult lifespan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903105 downregulation of insulin receptor signalling pathway of determination of adult lifespan|downregulation of daf-2 receptor signaling pathway of determination of adult lifespan|down-regulation of insulin receptor signaling pathway involved in determination of adult lifespan|down regulation of insulin receptor signalling pathway of determination of adult lifespan|down regulation of insulin receptor signaling pathway of determination of adult lifespan|inhibition of insulin receptor signalling pathway of determination of adult lifespan|downregulation of insulin receptor signaling pathway of determination of adult lifespan|down-regulation of daf-2 receptor signaling pathway of determination of adult lifespan|negative regulation of daf-2 receptor signaling pathway of determination of adult lifespan|downregulation of insulin receptor signaling pathway involved in determination of adult lifespan|down regulation of insulin receptor signaling pathway involved in determination of adult lifespan|inhibition of insulin receptor signaling pathway involved in determination of adult lifespan|down-regulation of insulin receptor signaling pathway of determination of adult lifespan|negative regulation of insulin receptor signaling pathway of determination of adult lifespan|inhibition of daf-2 receptor signaling pathway of determination of adult lifespan|down-regulation of insulin receptor signalling pathway of determination of adult lifespan|negative regulation of insulin receptor signalling pathway of determination of adult lifespan|inhibition of insulin receptor signaling pathway of determination of adult lifespan|down regulation of daf-2 receptor signaling pathway of determination of adult lifespan Any process that stops, prevents or reduces the frequency, rate or extent of insulin receptor signaling pathway involved in determination of adult lifespan. GO:1903104 regulation of insulin receptor signaling pathway involved in determination of adult lifespan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903104 regulation of daf-2 receptor signaling pathway of determination of adult lifespan|regulation of insulin receptor signalling pathway of determination of adult lifespan|regulation of insulin receptor signaling pathway of determination of adult lifespan Any process that modulates the frequency, rate or extent of insulin receptor signaling pathway involved in determination of adult lifespan. GO:1903103 potassium:proton antiporter complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1903103 A protein complex which is capable of potassium:proton antiporter activity. GO:1903102 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903102 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate biosynthesis|1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate anabolism|1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate synthesis|1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate formation The chemical reactions and pathways resulting in the formation of 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate. GO:1903101 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903101 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate breakdown|1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate catabolism|1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate degradation The chemical reactions and pathways resulting in the breakdown of 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate. GO:1903111 negative regulation of single-strand break repair via homologous recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903111 inhibition of single-strand break repair via homologous recombination|down regulation of single-strand break repair via homologous recombination|downregulation of single-strand break repair via homologous recombination|down-regulation of single-strand break repair via homologous recombination Any process that stops, prevents or reduces the frequency, rate or extent of single-strand break repair via homologous recombination. GO:1903110 regulation of single-strand break repair via homologous recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903110 Any process that modulates the frequency, rate or extent of single-strand break repair via homologous recombination. UBERON:0011745 pulmonary valve leaflets biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011745 A cardiac valve leaflet that is part of a pulmonary valve. CHEBI:28579 epsilon-caprolactam biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28579 CHEBI:28578 2-hydroxyglutaryl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28578 GO:1903119 protein localization to actin cytoskeleton biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903119 protein localisation in actin cytoskeleton|protein localization in actin cytoskeleton|protein localisation to actin cytoskeleton A process in which a protein is transported to, or maintained in, the location of an actin cytoskeleton. GO:1903118 urate homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903118 Any process involved in the maintenance of an internal steady state of urate within an organism or cell. GO:1903117 regulation of actin filament organization involved in cytokinetic actomyosin contractile ring assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903117 regulation of actin filament organisation of constriction ring assembly|regulation of actin filament organization of contractile ring assembly|regulation of regulation of actin filament localization of cytokinesis, actomyosin ring formation|regulation of actin filament organization of cytokinesis, actomyosin contractile ring assembly|regulation of actin filament organization of cytokinesis, actomyosin contractile ring formation|regulation of actin filament organization of constriction ring assembly|regulation of regulation of actin filament localization of cytokinesis, actomyosin ring biosynthesis|regulation of actin filament organisation of contractile ring assembly|regulation of regulation of actin filament localization of cytokinesis, contractile ring assembly|regulation of actin filament organisation of cytokinesis, actomyosin contractile ring assembly|regulation of actin filament organisation of cytokinesis, actomyosin ring formation|regulation of regulation of actin filament localization of cytokinesis, actomyosin contractile ring formation|regulation of regulation of actin filament localization of constriction ring assembly|regulation of actin filament organization of cytokinesis, actomyosin ring biosynthesis|regulation of actin filament organization of cytokinesis, actomyosin ring formation|regulation of actin filament organisation of cytokinesis, contractile ring assembly|regulation of regulation of actin filament localization of contractile ring assembly|regulation of actin filament organisation of cytokinesis, actomyosin ring biosynthesis|regulation of regulation of actin filament localization of cytokinesis, actomyosin contractile ring assembly|regulation of actin filament organization of cytokinesis, contractile ring assembly|regulation of actin filament organisation of cytokinesis, actomyosin contractile ring formation Any process that modulates the frequency, rate or extent of actin filament organization involved in cytokinetic actomyosin contractile ring assembly. GO:1903116 positive regulation of actin filament-based movement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903116 upregulation of actin filament-based movement|up regulation of actin filament-based movement|activation of actin filament-based movement|up-regulation of actin filament-based movement Any process that activates or increases the frequency, rate or extent of actin filament-based movement. UBERON:0011742 aortic valve leaflet biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011742 aortic valve leaflets A cardiac valve leaflet that is part of a aortic valve. GO:1903115 regulation of actin filament-based movement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903115 Any process that modulates the frequency, rate or extent of actin filament-based movement. UBERON:0011741 cardiac valve leaflet biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011741 valve leaflet GO:1903114 silver ion transmembrane transporter complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1903114 A protein complex which is capable of silver ion transmembrane transporter activity. GO:1903113 copper ion transmembrane transporter complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1903113 A protein complex which is capable of copper ion transmembrane transporter activity. CHEBI:28573 (R)-3-hydroxyoctanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28573 GO:1903112 positive regulation of single-strand break repair via homologous recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903112 up-regulation of single-strand break repair via homologous recombination|upregulation of single-strand break repair via homologous recombination|up regulation of single-strand break repair via homologous recombination|activation of single-strand break repair via homologous recombination Any process that activates or increases the frequency, rate or extent of single-strand break repair via homologous recombination. GO:1903122 negative regulation of TRAIL-activated apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903122 negative regulation of TRAIL-activated extrinsic apoptotic signaling pathway|down-regulation of TRAIL-activated extrinsic apoptotic signaling pathway|inhibition of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|inhibition of TRAIL-induced apoptotic signaling pathway|inhibition of TRAIL-activated extrinsic apoptotic signaling pathway|down regulation of TRAIL-activated apoptotic signaling pathway|downregulation of TRAIL-activated apoptotic signaling pathway|down regulation of TRAIL-induced apoptotic signaling pathway|down regulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|downregulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|downregulation of TRAIL-induced apoptotic signaling pathway|down regulation of TRAIL-activated extrinsic apoptotic signaling pathway|downregulation of TRAIL-activated extrinsic apoptotic signaling pathway|down-regulation of TRAIL-activated apoptotic signaling pathway|negative regulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|down-regulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|down-regulation of TRAIL-induced apoptotic signaling pathway|negative regulation of TRAIL-induced apoptotic signaling pathway|inhibition of TRAIL-activated apoptotic signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of TRAIL-activated apoptotic signaling pathway. PR:000050043 lymphotoxin biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000050043 fam:LT A tumor necrosis factor, TNF-like that is a translation product of the human LTA or LTB genes, or 1:1 orthologs thereof. GO:1903121 regulation of TRAIL-activated apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903121 regulation of TRAIL-induced apoptotic signaling pathway|regulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|regulation of TRAIL-activated extrinsic apoptotic signaling pathway Any process that modulates the frequency, rate or extent of TRAIL-activated apoptotic signaling pathway. GO:1903120 protein localization to actin filament bundle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903120 protein localisation to actin filament bundle|protein localization to actin cable|protein localization in actin filament bundle|protein localisation in actin filament bundle A process in which a protein is transported to, or maintained in, the location of an actin filament bundle. CHEBI:7351 N(4)-acetyl-L-2,4-diaminobutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_7351 CHEBI:28549 3-(indol-3-yl)-2-oxobutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28549 CHEBI:53508 thyroxine sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53508 CHEBI:28548 D-pinitol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28548 CHEBI:28547 D-glucuronate 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28547 CHEBI:28542 2-deoxy-D-ribofuranose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28542 GO:1903129 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1903129 CHEBI:28541 N-acetylneuraminyl-(2->8)-N-acetylneuraminyl-(2->8)-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphingosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28541 PR:000001092 interleukin-17 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001092 IL17|fam:IL-17 A protein that is a T cell-derived cytokine that may play an important role in the initiation or maintenance of the proinflammatory response. Except for IL-17B, all other IL-17 family members are homodimers containing five highly conserved cysteine residues forming characteristic cystein-knot structure, similar to that found in the TGF-beta-like cystine-knot (PR:000000008). This class consists of six cytokines. Among them, interleukin 17A (IL-17) and IL-17F are expressed by a novel subset of CD4+ helper T (Th) cells and play a critical role in inflammation and autoimmunity. On the other hand, IL-17E, also called IL-25, has been associated with allergic responses. GO:1903128 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1903128 GO:1903127 positive regulation of centriole-centriole cohesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903127 upregulation of centriole-centriole cohesion|up-regulation of centriole-centriole cohesion|activation of centriole-centriole cohesion|up regulation of centriole-centriole cohesion Any process that activates or increases the frequency, rate or extent of centriole-centriole cohesion. PR:000001091 interleukin-1 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001091 A protein with a core domain composition consisting of a propeptide region and an Interleukin-1 / 18 domain. PR:000001094 rhodopsin-like G-protein coupled receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001094 fam:rhodopsin|class A G-protein coupled receptor|class 1 G-protein coupled receptor A G-protein coupled receptor that contains the 7 transmembrane receptor (rhodopsin family) domain (Pfam:PF00001), which includes 7 transmembrane helices (TMI-TM7) with 3 intracellular loops (IL1-IL3) and 3 extracellular loops (EL1-EL3) between the helices. The amino-terminal region is extracellular and the carboxyl-terminal region is intracellular. Rhodopsin-like G-protein coupled receptors (GPCRs) are unique among the several classes of GPCRs in that most have a very short amino-terminal segment and several characteristic sequence motifs, particularly NSxxNPxxY in TM7 and D/E-R-Y/F between TM3 and loop IL2. Most bind their ligands within a cavity between the TM regions. GO:1903126 negative regulation of centriole-centriole cohesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903126 down regulation of centriole-centriole cohesion|inhibition of centriole-centriole cohesion|down-regulation of centriole-centriole cohesion|downregulation of centriole-centriole cohesion Any process that stops, prevents or reduces the frequency, rate or extent of centriole-centriole cohesion. GO:1903125 negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903125 negative regulation of TPx activity by peptidyl-threonine phosphorylation|negative regulation of thiol peroxidase activity by peptidyl-threonine phosphorylation|negative regulation of TrxPx activity by peptidyl-threonine phosphorylation A peptidyl-threonine phosphorylation that results in negative regulation of thioredoxin peroxidase activity. PR:000001096 Toll-like receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001096 fam:TLR A protein with a core domain composition consisting of a signal peptide, an extracellular domain with multiple Leucine rich repeat (Pfam:PF13855) domain (LRR), a cysteine-rich region, a single-pass transmembrane domain and a C-terminal cytoplasmic tail containing a TIR domain (Pfam:PF01582). GO:1903124 negative regulation of thioredoxin peroxidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903124 inhibition of thiol peroxidase activity|down-regulation of TrxPx activity|negative regulation of TrxPx activity|downregulation of TPx activity|down-regulation of thioredoxin peroxidase activity|down regulation of TPx activity|inhibition of TPx activity|downregulation of TrxPx activity|inhibition of thioredoxin peroxidase activity|down regulation of thiol peroxidase activity|down regulation of TrxPx activity|inhibition of TrxPx activity|downregulation of thiol peroxidase activity|down-regulation of TPx activity|negative regulation of thiol peroxidase activity|down regulation of thioredoxin peroxidase activity|negative regulation of TPx activity|down-regulation of thiol peroxidase activity|downregulation of thioredoxin peroxidase activity Any process that stops, prevents or reduces the frequency, rate or extent of thioredoxin peroxidase activity. PR:000001095 secretin-like G-protein coupled receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001095 subfamily B1 G-protein coupled receptor|class 2 G-protein coupled receptor|class B G-protein coupled receptor|fam:secretin A G-protein coupled receptor that contains the 7 transmembrane receptor (secretin family) domain (Pfam:PF00002) and has an amino-terminal segment of about 50-80 residues that contains conserved disulfide bonds and participates in ligand binding. GO:1903123 regulation of thioredoxin peroxidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903123 regulation of TPx activity|regulation of TrxPx activity|regulation of thiol peroxidase activity Any process that modulates the frequency, rate or extent of thioredoxin peroxidase activity. GO:1903133 negative regulation of tube lumen cavitation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903133 inhibition of tube lumen cavitation Any process that stops, prevents or reduces the frequency, rate or extent of tube lumen cavitation. GO:1903132 regulation of tube lumen cavitation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903132 Any process that modulates the frequency, rate or extent of tube lumen cavitation. GO:1903131 mononuclear cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903131 The process in which a relatively unspecialized cell acquires the specialized features of a mononuclear cell. GO:1903130 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1903130 CHEBI:28557 cyclohexane-1-carbonyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28557 CHEBI:28556 biochanin A 7-O-(6-O-malonyl-beta-D-glucoside) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28556 CHEBI:28558 2,5-dichloro-cis,cis-muconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28558 GO:1903139 positive regulation of cell wall integrity MAPK cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903139 positive regulation of MAPK cascade involved in cell wall organization or biogenesis|upregulation of cell integrity MAPK pathway|positive regulation of Pmk1 MAPK cell integrity signaling|positive regulation of Mpk1 cascade|up regulation of Mpk1 cascade|up regulation of Pmk1 MAPK cell integrity signaling|upregulation of MAPK cascade involved in cell wall organization or biogenesis|up-regulation of PMK1-MAPK signal transduction pathway|up-regulation of MAPK cascade involved in cell wall biogenesis|up-regulation of Slt2 cascade|up regulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|up-regulation of cell wall biogenesis, MAPKKK cascade|activation of cell wall biogenesis, MAPKKK cascade|up-regulation of MAPKKK cascade involved in cell wall biogenesis|up regulation of cell integrity MAPK pathway|positive regulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|activation of cell integrity MAPK pathway|positive regulation of cell integrity MAPK pathway|upregulation of Mpk1 cascade|upregulation of PMK1-MAPK signal transduction pathway|upregulation of Pmk1 MAPK cell integrity signaling|activation of Slt2 cascade|up regulation of MAPK cascade involved in cell wall organization or biogenesis|upregulation of MAPK cascade involved in cell wall biogenesis|activation of MAPK cascade involved in cell wall organization or biogenesis|activation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|positive regulation of Slt2 cascade|positive regulation of cell wall biogenesis, MAPKKK cascade|upregulation of MAPKKK cascade involved in cell wall biogenesis|up regulation of Slt2 cascade|up regulation of cell wall biogenesis, MAPKKK cascade|up-regulation of Mpk1 cascade|up-regulation of Pmk1 MAPK cell integrity signaling|up-regulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|up regulation of PMK1-MAPK signal transduction pathway|up-regulation of cell integrity MAPK pathway|positive regulation of PMK1-MAPK signal transduction pathway|up regulation of MAPK cascade involved in cell wall biogenesis|up-regulation of MAPK cascade involved in cell wall organization or biogenesis|positive regulation of MAPK cascade involved in cell wall biogenesis|activation of Pmk1 MAPK cell integrity signaling|activation of Mpk1 cascade|activation of PMK1-MAPK signal transduction pathway|up regulation of MAPKKK cascade involved in cell wall biogenesis|upregulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|upregulation of Slt2 cascade|activation of MAPKKK cascade involved in cell wall biogenesis|activation of MAPK cascade involved in cell wall biogenesis|positive regulation of MAPKKK cascade involved in cell wall biogenesis|upregulation of cell wall biogenesis, MAPKKK cascade Any process that activates or increases the frequency, rate or extent of MAPK cascade involved in cell wall organization or biogenesis. GO:1903138 negative regulation of cell wall integrity MAPK cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903138 down regulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|inhibition of Slt2 cascade|negative regulation of MAPKKK cascade involved in cell wall biogenesis|down-regulation of MAPKKK cascade involved in cell wall biogenesis|down regulation of cell integrity MAPK pathway|downregulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|downregulation of Pmk1 MAPK cell integrity signaling|negative regulation of MAPK cascade involved in cell wall organization or biogenesis|downregulation of Mpk1 cascade|down regulation of MAPK cascade involved in cell wall organization or biogenesis|downregulation of cell integrity MAPK pathway|inhibition of PMK1-MAPK signal transduction pathway|down regulation of Mpk1 cascade|down regulation of Pmk1 MAPK cell integrity signaling|inhibition of MAPKKK cascade involved in cell wall biogenesis|inhibition of MAPK cascade involved in cell wall biogenesis|downregulation of MAPK cascade involved in cell wall organization or biogenesis|down-regulation of Slt2 cascade|down-regulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|negative regulation of Slt2 cascade|negative regulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|down regulation of PMK1-MAPK signal transduction pathway|inhibition of Pmk1 MAPK cell integrity signaling|down-regulation of cell wall biogenesis, MAPKKK cascade|negative regulation of cell wall biogenesis, MAPKKK cascade|inhibition of Mpk1 cascade|down regulation of MAPK cascade involved in cell wall biogenesis|negative regulation of cell integrity MAPK pathway|down-regulation of cell integrity MAPK pathway|downregulation of PMK1-MAPK signal transduction pathway|down-regulation of MAPK cascade involved in cell wall organization or biogenesis|downregulation of MAPK cascade involved in cell wall biogenesis|downregulation of Slt2 cascade|inhibition of cell integrity MAPK pathway|down regulation of MAPKKK cascade involved in cell wall biogenesis|downregulation of cell wall biogenesis, MAPKKK cascade|inhibition of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|inhibition of MAPK cascade involved in cell wall organization or biogenesis|downregulation of MAPKKK cascade involved in cell wall biogenesis|down regulation of Slt2 cascade|down-regulation of PMK1-MAPK signal transduction pathway|negative regulation of PMK1-MAPK signal transduction pathway|down-regulation of Pmk1 MAPK cell integrity signaling|negative regulation of Mpk1 cascade|down-regulation of Mpk1 cascade|negative regulation of Pmk1 MAPK cell integrity signaling|down regulation of cell wall biogenesis, MAPKKK cascade|down-regulation of MAPK cascade involved in cell wall biogenesis|inhibition of cell wall biogenesis, MAPKKK cascade|negative regulation of MAPK cascade involved in cell wall biogenesis Any process that stops, prevents or reduces the frequency, rate or extent of MAPK cascade involved in cell wall organization or biogenesis. CHEBI:28554 ajugose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28554 GO:1903137 regulation of cell wall integrity MAPK cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903137 regulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|regulation of cell integrity MAPK pathway|regulation of Mpk1 cascade|regulation of Pmk1 MAPK cell integrity signaling|regulation of PMK1-MAPK signal transduction pathway|regulation of MAPK cascade involved in cell wall biogenesis|regulation of MAPKKK cascade involved in cell wall biogenesis|regulation of MAPK cascade involved in cell wall organization or biogenesis|regulation of Slt2 cascade|regulation of cell wall biogenesis, MAPKKK cascade Any process that modulates the frequency, rate or extent of MAPK cascade involved in cell wall organization or biogenesis. GO:1903136 cuprous ion binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1903136 Cu(I) binding|copper(1+) binding|Cu(+) binding Interacting selectively and non-covalently with cuprous ion, copper(1+). GO:1903135 cupric ion binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1903135 Cu(II) binding|copper(2+)binding|Cu(2+) binding Interacting selectively and non-covalently with cupric ion, copper(2+). GO:1903134 obsolete trehalose catabolic process involved in cellular response to stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903134 mycose catabolic process involved in cellular response to stress|mycose catabolism involved in cellular response to stress|mykose catabolic process involved in cellular response to stress|trehalose degradation involved in cellular response to stress|trehalose catabolism involved in cellular response to stress|trehalose breakdown involved in cellular response to stress|mykose catabolism involved in cellular response to stress OBSOLETE. Any trehalose catabolic process that is involved in cellular response to stress. GO:1903144 actomyosin contractile ring actin filament biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1903144 actin filament of actomyosin contractile ring|actin filament of contractile actomyosin ring|actin filament of actomyosin ring|actin filament of cytokinetic ring|actin filament of CAR Any actin filament that is part of a actomyosin contractile ring. GO:1903143 adrenomedullin receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1903143 adrenomedullin receptor AM2 complex|adrenomedullin receptor AM1 complex A transmembrane, G protein-coupled signalling receptor complex which is capable of adrenomedullin receptor activity. GO:1903142 positive regulation of establishment of endothelial barrier biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903142 up-regulation of establishment of endothelial barrier|activation of establishment of endothelial barrier|up regulation of establishment of endothelial barrier|upregulation of establishment of endothelial barrier Any process that activates or increases the frequency, rate or extent of establishment of endothelial barrier. GO:1903141 negative regulation of establishment of endothelial barrier biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903141 down-regulation of establishment of endothelial barrier|downregulation of establishment of endothelial barrier|down regulation of establishment of endothelial barrier|inhibition of establishment of endothelial barrier Any process that stops, prevents or reduces the frequency, rate or extent of establishment of endothelial barrier. GO:1903140 regulation of establishment of endothelial barrier biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903140 Any process that modulates the frequency, rate or extent of establishment of endothelial barrier. CHEBI:28528 3-oxodecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28528 CHEBI:28526 (KDO)2-lipid IVA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28526 CHEBI:28522 4-hydroxybutyryl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28522 GO:1903149 obsolete adenine transmembrane transporter activity involved in adenine import into cell biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1903149 adenine transmembrane transporter activity involved in adenine import into cell OBSOLETE. Any adenine transmembrane transporter activity that is involved in adenine import into cell. GO:1903148 obsolete uracil transmembrane transporter activity involved in uracil import into cell biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1903148 uracil/uridine permease activity involved in uracil import into cell|uracil transmembrane transporter activity involved in uracil import into cell OBSOLETE. Any uracil transmembrane transporter activity that is involved in uracil import into cell. GO:1903147 negative regulation of autophagy of mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903147 down regulation of mitochondrion degradation|downregulation of mitochondrion degradation|inhibition of mitophagy|down-regulation of mitochondrion degradation|down-regulation of mitophagy|inhibition of mitochondrion degradation|down regulation of mitochondrial degradation Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrion degradation by autophagy. GO:1903146 regulation of autophagy of mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903146 regulation of mitochondrion degradation Any process that modulates the frequency, rate or extent of mitochondrion degradation by an autophagic process. GO:1903145 actin filament of cell cortex of cell tip biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1903145 microfilament of cell cortex of cell end|microfilament of cell cortex of cell tip|actin filament of cell cortex of cell end Any actin filament that is part of a cell cortex of cell tip. GO:1903155 obsolete glutathione transmembrane transporter activity involved in glutathione import into cell biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1903155 glutathione transmembrane transporter activity involved in glutathione uptake|glutathione transmembrane transporter activity involved in glutathione import into cell OBSOLETE. Any glutathione transmembrane transporter activity that is involved in glutathione import into cell. GO:1903154 obsolete glucose transmembrane transporter activity involved in glucose import into cell biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1903154 galactose/glucose (methylgalactoside) porter activity involved in glucose import into cell|glucose permease activity involved in glucose import into cell|glucose transmembrane transporter activity involved in glucose import into cell|lactose/glucose efflux transporter activity involved in glucose import into cell OBSOLETE. Any glucose transmembrane transporter activity that is involved in glucose import into cell. GO:1903153 obsolete ferrous iron transmembrane transporter activity involved in ferrous iron import into cell biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1903153 ferrous iron transmembrane transporter activity involved in ferrous ion import into cell|ferrous iron transmembrane transporter activity involved in ferrous iron import into cell OBSOLETE. Any ferrous iron transmembrane transporter activity that is involved in ferrous iron import into cell. GO:1903152 obsolete copper ion transmembrane transporter activity involved in copper ion import into cell biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1903152 copper ion transmembrane transporter activity involved in copper cation import into cell|copper ion transmembrane transporter activity involved in copper ion import into cell|plasma membrane copper transporter involved in copper ion import into cell|intracellular copper ion transporter involved in copper cation import into cell|intracellular copper ion transporter involved in copper ion import into cell|plasma membrane copper transporter involved in copper cation import into cell OBSOLETE. Any copper ion transmembrane transporter activity that is involved in copper ion import into cell. GO:1903151 obsolete carbohydrate transmembrane transporter activity involved in carbohydrate import into cell biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1903151 carbohydrate transmembrane transporter activity involved in carbohydrate import into cell|sugar transporter involved in carbohydrate import into cell OBSOLETE. Any carbohydrate transmembrane transporter activity that is involved in carbohydrate import into cell. GO:1903150 obsolete calcium ion transmembrane transporter activity involved in calcium ion import into cell biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1903150 calcium ion transmembrane transporter activity involved in calcium ion uptake into cell|calcium ion transmembrane transporter activity involved in calcium ion import into cell OBSOLETE. Any calcium ion transmembrane transporter activity that is involved in calcium ion import into cell. CHEBI:7386 4-acetamidobutanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_7386 CHEBI:28538 N(omega)-hydroxy-L-arginine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28538 CHEBI:28537 all-trans-dehydroretinal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28537 CHEBI:28536 3-hydroxyindolin-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28536 CHEBI:28531 cob(I)yrinic acid a,c diamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28531 CHEBI:28533 3alpha,7alpha-dihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28533 GO:1903159 obsolete malate transmembrane transporter activity involved in malate import into cell biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1903159 dicarboxylate (succinate/fumarate/malate) antiporter activity involved in malate import into cell|malate transmembrane transporter activity involved in malate import into cell OBSOLETE. Any malate transmembrane transporter activity that is involved in malate import into cell. GO:1903158 obsolete L-glutamate transmembrane transporter activity involved in L-glutamate import into cell biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1903158 glutamate/aspartate porter activity involved in L-glutamate import into cell|glutamate/aspartate:sodium symporter activity involved in L-glutamate import into cell|L-glutamate transmembrane transporter activity involved in L-glutamate import into cell OBSOLETE. Any L-glutamate transmembrane transporter activity that is involved in L-glutamate import into cell. GO:1903157 obsolete iron ion transmembrane transporter activity involved in iron ion import into cell biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1903157 transmembrane iron permease activity involved in iron import into cell|transmembrane iron permease activity involved in iron ion import into cell|iron ion transmembrane transporter activity involved in iron ion import into cell|iron transporter activity involved in iron import into cell|zinc, iron permease activity involved in iron import into cell|iron transporter activity involved in iron ion import into cell|iron ion transmembrane transporter activity involved in iron import into cell|multicopper ferroxidase iron transport mediator activity involved in iron import into cell|zinc, iron permease activity involved in iron ion import into cell|transmembrane iron ion permease activity involved in iron import into cell|transmembrane iron ion permease activity involved in iron ion import into cell|multicopper ferroxidase iron transport mediator activity involved in iron ion import into cell OBSOLETE. Any iron ion transmembrane transporter activity that is involved in iron ion import into cell. GO:1903156 obsolete guanine transmembrane transporter activity involved in guanine import into cell biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1903156 guanine transmembrane transporter activity involved in guanine import into cell OBSOLETE. Any guanine transmembrane transporter activity that is involved in guanine import into cell. GO:1903166 cellular response to polycyclic arene biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903166 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polycyclic arene stimulus. UBERON:0011779 nerve of head region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011779 head nerve|cephalic nerve A nerve that is part of a head. UBERON:0011778 motor nucleus of vagal nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011778 vagal lobe|nucleus motorius of nervi vagi|motor nucleus of X|motor nucleus X|nX GO:1903165 response to polycyclic arene biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903165 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polycyclic arene stimulus. UBERON:0011777 nucleus of spinal cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011777 spinal cord nucleus A neural nucleus that is part of the spinal cord. GO:1903164 obsolete succinate transmembrane transporter activity involved in succinate import into cell biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1903164 succinate transmembrane transporter activity involved in succinate import into cell|dicarboxylate (succinate/fumarate/malate) antiporter activity involved in succinate import into cell OBSOLETE. Any succinate transmembrane transporter activity that is involved in succinate import into cell. GO:1903163 obsolete sodium ion transmembrane transporter activity involved in sodium ion import into cell biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1903163 sodium transporter activity involved in sodium ion import into cell|sodium ion transmembrane transporter activity involved in sodium ion import into cell OBSOLETE. Any sodium ion transmembrane transporter activity that is involved in sodium ion import into cell. GO:1903162 obsolete serine transmembrane transporter activity involved in serine import into cell biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1903162 serine transmembrane transporter activity involved in serine import into cell OBSOLETE. Any serine transmembrane transporter activity that is involved in serine import into cell. GO:1903161 obsolete pantothenate transmembrane transporter activity involved in pantothenate import into cell biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1903161 pantothenate transmembrane transporter activity involved in pantothenate import into cell|vitamin B5 transmembrane transporter activity involved in pantothenate import into cell OBSOLETE. Any pantothenate transmembrane transporter activity that is involved in pantothenate import into cell. GO:1903160 obsolete nickel cation transmembrane transporter activity involved in nickel cation import into cell biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1903160 nickel cation transmembrane transporter activity involved in nickel cation import into cell|zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity involved in nickel cation import into cell OBSOLETE. Any nickel cation transmembrane transporter activity that is involved in nickel cation import into cell. CHEBI:28506 arsonoacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28506 CHEBI:28507 cytidine 2'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28507 UBERON:0011775 vagus nerve nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011775 nucleus of Xth nerve|vagal nucleus|nucleus of vagal nerve|vagal X nucleus|vagus nucleus|nucleus of vagal X nerve|nucleus of vagus nerve|tenth cranial nerve nucleus|nodosal nucleus A cranial nerve nucleus that is associated with a vagus nerve. GO:1903169 regulation of calcium ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903169 regulation of transmembrane calcium transport|regulation of calcium ion membrane transport Any process that modulates the frequency, rate or extent of calcium ion transmembrane transport. GO:1903168 positive regulation of pyrroline-5-carboxylate reductase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903168 up-regulation of L-proline oxidase activity|activation of L-proline oxidase activity|upregulation of L-proline-NAD(P)+ 5-oxidoreductase activity|up regulation of P5CR activity|upregulation of pyrroline-5-carboxylate reductase activity|positive regulation of P5CR activity|activation of P5CR activity|up-regulation of L-proline:NAD(P)+ 5-oxidoreductase activity|upregulation of NADPH-L-delta1-pyrroline carboxylic acid reductase activity|upregulation of 1-pyrroline-5-carboxylate reductase activity|positive regulation of L-proline oxidase activity|up regulation of L-proline-NAD(P)+ 5-oxidoreductase activity|up-regulation of pyrroline-5-carboxylate reductase activity|activation of pyrroline-5-carboxylate reductase activity|positive regulation of L-proline-NAD(P)+ 5-oxidoreductase activity|up regulation of L-proline oxidase activity|activation of L-proline-NAD(P)+ 5-oxidoreductase activity|upregulation of L-proline:NAD(P)+ 5-oxidoreductase activity|up-regulation of P5CR activity|up regulation of NADPH-L-delta1-pyrroline carboxylic acid reductase activity|up-regulation of 1-pyrroline-5-carboxylate reductase activity|activation of 1-pyrroline-5-carboxylate reductase activity|positive regulation of NADPH-L-delta1-pyrroline carboxylic acid reductase activity|activation of NADPH-L-delta1-pyrroline carboxylic acid reductase activity|upregulation of L-proline oxidase activity|up-regulation of L-proline-NAD(P)+ 5-oxidoreductase activity|upregulation of P5CR activity|up regulation of L-proline:NAD(P)+ 5-oxidoreductase activity|up regulation of pyrroline-5-carboxylate reductase activity|activation of L-proline:NAD(P)+ 5-oxidoreductase activity|positive regulation of L-proline:NAD(P)+ 5-oxidoreductase activity|positive regulation of 1-pyrroline-5-carboxylate reductase activity|up regulation of 1-pyrroline-5-carboxylate reductase activity|up-regulation of NADPH-L-delta1-pyrroline carboxylic acid reductase activity Any process that activates or increases the frequency, rate or extent of pyrroline-5-carboxylate reductase activity. UBERON:0011773 upper jaw opening biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011773 An anatomical space that is part of a bone of upper jaw. GO:1903167 regulation of pyrroline-5-carboxylate reductase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903167 regulation of 1-pyrroline-5-carboxylate reductase activity|regulation of L-proline-NAD(P)+ 5-oxidoreductase activity|regulation of NADPH-L-delta1-pyrroline carboxylic acid reductase activity|regulation of L-proline oxidase activity|regulation of L-proline:NAD(P)+ 5-oxidoreductase activity|regulation of P5CR activity Any process that modulates the frequency, rate or extent of pyrroline-5-carboxylate reductase activity. UBERON:0011772 lower jaw opening biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011772 An anatomical space that is part of a bone of lower jaw. GO:1903177 negative regulation of tyrosine 3-monooxygenase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903177 downregulation of tyrosine hydroxylase activity|down-regulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|downregulation of L-tyrosine hydroxylase activity|negative regulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|down regulation of tyrosine 3-hydroxylase activity|downregulation of tyrosine 3-hydroxylase activity|down-regulation of tyrosine 3-monooxygenase activity|negative regulation of tyrosine hydroxylase activity|down-regulation of tyrosine hydroxylase activity|down-regulation of L-tyrosine hydroxylase activity|negative regulation of L-tyrosine hydroxylase activity|downregulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|inhibition of tyrosine 3-monooxygenase activity|down regulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|down-regulation of tyrosine 3-hydroxylase activity|negative regulation of tyrosine 3-hydroxylase activity|inhibition of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|inhibition of tyrosine hydroxylase activity|inhibition of L-tyrosine hydroxylase activity|inhibition of tyrosine 3-hydroxylase activity|down regulation of tyrosine 3-monooxygenase activity|down regulation of tyrosine hydroxylase activity|down regulation of L-tyrosine hydroxylase activity|downregulation of tyrosine 3-monooxygenase activity Any process that stops, prevents or reduces the frequency, rate or extent of tyrosine 3-monooxygenase activity. GO:1903176 regulation of tyrosine 3-monooxygenase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903176 regulation of tyrosine 3-hydroxylase activity|regulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|regulation of tyrosine hydroxylase activity|regulation of L-tyrosine hydroxylase activity Any process that modulates the frequency, rate or extent of tyrosine 3-monooxygenase activity. UBERON:0011767 right recurrent laryngeal nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011767 vagus X nerve right recurrent laryngeal branch|right recurrent laryngeal nerve|right recurrent laryngeal branch GO:1903175 fatty alcohol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903175 fatty alcohol anabolism|fatty alcohol biosynthesis|fatty alcohol synthesis|fatty alcohol formation The chemical reactions and pathways resulting in the formation of fatty alcohol. UBERON:0011766 left recurrent laryngeal nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011766 left recurrent laryngeal branch|vagus X nerve left recurrent laryngeal branch|left recurrent laryngeal nerve GO:1903174 fatty alcohol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903174 fatty alcohol degradation|fatty alcohol breakdown|fatty alcohol catabolism The chemical reactions and pathways resulting in the breakdown of fatty alcohol. GO:1903173 fatty alcohol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903173 fatty alcohol metabolism The chemical reactions and pathways involving fatty alcohol. GO:1903172 cellular carbon dioxide homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903172 Any biological process involved in the maintenance of an internal steady state of carbon dioxide at the level of the cell. GO:1903171 carbon dioxide homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903171 Any process involved in the maintenance of an internal steady state of carbon dioxide within an organism or cell. UBERON:0011769 cartilaginous projection biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011769 cartilaginous process|cartilage process Anatomical projection that is composed of cartilage tissue. GO:1903170 negative regulation of calcium ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903170 inhibition of transmembrane calcium transport|down regulation of calcium ion transmembrane transport|negative regulation of calcium ion membrane transport|down-regulation of calcium ion membrane transport|downregulation of calcium ion transmembrane transport|down regulation of transmembrane calcium transport|downregulation of calcium ion membrane transport|downregulation of transmembrane calcium transport|down-regulation of calcium ion transmembrane transport|down regulation of calcium ion membrane transport|inhibition of calcium ion membrane transport|inhibition of calcium ion transmembrane transport|negative regulation of transmembrane calcium transport|down-regulation of transmembrane calcium transport Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transport. CHEBI:28517 biphenyl-2,2',3-triol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28517 CHEBI:28516 1,2-dihydronaphthalene-1,2-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28516 CHEBI:28518 alpha-D-xylose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28518 CHEBI:28514 N-acetyl-D-glucosaminyl-(1->4)-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28514 GO:1903179 regulation of dopamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903179 regulation of dopamine formation|regulation of dopamine biosynthesis|regulation of dopamine anabolism|regulation of dopamine synthesis Any process that modulates the frequency, rate or extent of dopamine biosynthetic process. GO:1903178 positive regulation of tyrosine 3-monooxygenase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903178 upregulation of tyrosine 3-hydroxylase activity|up regulation of tyrosine 3-monooxygenase activity|up regulation of tyrosine hydroxylase activity|activation of tyrosine 3-monooxygenase activity|up regulation of L-tyrosine hydroxylase activity|stimulation of TH activity|positive regulation of tyrosine hydroxylase activity|positive regulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|activation of tyrosine hydroxylase activity|positive regulation of L-tyrosine hydroxylase activity|activation of L-tyrosine hydroxylase activity|up regulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|up regulation of tyrosine 3-hydroxylase activity|positive regulation of tyrosine 3-hydroxylase activity|activation of tyrosine 3-hydroxylase activity|up-regulation of tyrosine 3-monooxygenase activity|up-regulation of tyrosine hydroxylase activity|up-regulation of L-tyrosine hydroxylase activity|upregulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|up-regulation of tyrosine 3-hydroxylase activity|upregulation of tyrosine 3-monooxygenase activity|upregulation of tyrosine hydroxylase activity|up-regulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|upregulation of L-tyrosine hydroxylase activity|activation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|positive regulation of TH activity Any process that activates or increases the frequency, rate or extent of tyrosine 3-monooxygenase activity. GO:1903188 positive regulation of vitellogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903188 up-regulation of vitellogenesis|activation of vitellogenesis|up-regulation of yolk production|upregulation of yolk production|up regulation of vitellogenesis|up regulation of yolk production|upregulation of vitellogenesis|positive regulation of yolk production|activation of yolk production Any process that activates or increases the frequency, rate or extent of vitellogenesis. UBERON:0011757 differentiated genital tubercle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011757 primordial phallus|phallus primordialis|phallus . GO:1903187 negative regulation of vitellogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903187 inhibition of yolk production|down-regulation of vitellogenesis|down regulation of yolk production|downregulation of vitellogenesis|downregulation of yolk production|down regulation of vitellogenesis|inhibition of vitellogenesis|negative regulation of yolk production|down-regulation of yolk production Any process that stops, prevents or reduces the frequency, rate or extent of vitellogenesis. GO:1903186 regulation of vitellogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903186 regulation of yolk production Any process that modulates the frequency, rate or extent of vitellogenesis. GO:1903185 L-dopa biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903185 L-dopa anabolism|L-dopa synthesis|L-dopa biosynthesis|L-dopa formation The chemical reactions and pathways resulting in the formation of L-dopa. GO:1903184 L-dopa metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903184 L-dopa metabolism The chemical reactions and pathways involving L-dopa. GO:1903183 negative regulation of SUMO transferase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903183 downregulation of SUMO ligase activity|downregulation of SUMO conjugating enzyme activity|downregulation of SMT3 conjugating enzyme|down regulation of SUMO ligase activity|inhibition of SUMO ligase activity|down regulation of SUMO conjugating enzyme activity|inhibition of SUMO conjugating enzyme activity|negative regulation of SMT3 conjugating enzyme|down-regulation of SMT3 conjugating enzyme|inhibition of SMT3 conjugating enzyme|down-regulation of SUMO ligase activity|negative regulation of SUMO conjugating enzyme activity|down-regulation of SUMO conjugating enzyme activity|down regulation of SMT3 conjugating enzyme Any process that stops, prevents or reduces the frequency, rate or extent of SUMO ligase activity. GO:1903182 regulation of SUMO transferase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903182 regulation of SMT3 conjugating enzyme|regulation of SUMO conjugating enzyme activity Any process that modulates the frequency, rate or extent of SUMO ligase activity. GO:1903181 positive regulation of dopamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903181 up regulation of dopamine anabolism|positive regulation of dopamine synthesis|up regulation of dopamine synthesis|positive regulation of dopamine formation|up-regulation of dopamine biosynthesis|up-regulation of dopamine biosynthetic process|up regulation of dopamine formation|upregulation of dopamine anabolism|upregulation of dopamine synthesis|upregulation of dopamine biosynthetic process|upregulation of dopamine biosynthesis|upregulation of dopamine formation|up-regulation of dopamine anabolism|activation of dopamine anabolism|up-regulation of dopamine synthesis|activation of dopamine synthesis|up regulation of dopamine biosynthesis|up regulation of dopamine biosynthetic process|up-regulation of dopamine formation|activation of dopamine formation|positive regulation of dopamine biosynthesis|activation of dopamine biosynthetic process|activation of dopamine biosynthesis|positive regulation of dopamine anabolism Any process that activates or increases the frequency, rate or extent of dopamine biosynthetic process. GO:1903180 negative regulation of dopamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903180 negative regulation of dopamine formation|down-regulation of dopamine formation|downregulation of dopamine anabolism|inhibition of dopamine biosynthetic process|inhibition of dopamine biosynthesis|down regulation of dopamine anabolism|downregulation of dopamine synthesis|inhibition of dopamine anabolism|downregulation of dopamine formation|down regulation of dopamine synthesis|inhibition of dopamine synthesis|down regulation of dopamine formation|inhibition of dopamine formation|down regulation of dopamine biosynthetic process|down regulation of dopamine biosynthesis|downregulation of dopamine biosynthesis|downregulation of dopamine biosynthetic process|negative regulation of dopamine anabolism|down-regulation of dopamine anabolism|negative regulation of dopamine synthesis|down-regulation of dopamine synthesis|negative regulation of dopamine biosynthesis|down-regulation of dopamine biosynthetic process|down-regulation of dopamine biosynthesis Any process that stops, prevents or reduces the frequency, rate or extent of dopamine biosynthetic process. PR:000050029 thyrotropin-releasing hormone receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000050029 A rhodopsin-like G-protein coupled receptor that has thyrotropin-releasing hormone receptor activity. CHEBI:77450 dicarboxylic acid monoamide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77450 CHEBI:864 (S)-2,3,4,5-tetrahydrodipicolinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_864 CHEBI:53487 all-cis-docosa-7,10,13,16-tetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53487 CHEBI:53486 all-cis-icosa-8,11,14-trienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53486 CHEBI:77452 2-deoxystreptamine cation biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77452 CHEBI:53488 (7Z,10Z,13Z,16Z,19Z)-docosapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53488 CHEBI:77456 2-iminopropanoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77456 CHEBI:77460 L-aminoacyl-L-amino acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77460 CHEBI:77465 1-oleylglycerone 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77465 CHEBI:77469 1-pentadecylglycerone 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77469 CHEBI:77468 pentadecan-1-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77468 CHEBI:77467 1-tetradecylglycerone 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77467 CHEBI:77466 1-dodecylglycerone 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77466 GO:0004987 obsolete kappa-opioid receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004987 Wikipedia:Kappa_Opioid_receptor kappa-opioid receptor activity OBSOLETE. Combining with an opioid to initiate a change in cell activity, with the pharmacological characteristics of kappa-opioid receptors, including high affinity for dynorphins. GO:0004986 obsolete delta-opioid receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004986 Wikipedia:Delta_Opioid_receptor delta-opioid receptor activity OBSOLETE. Combining with an opioid to initiate a change in cell activity, with the pharmacological characteristics of delta-opioid receptors, including the activity of enkephalins as ligands. GO:0004989 octopamine receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004989 Combining with the biogenic amine octopamine to initiate a change in cell activity. Octopamine is found in both vertebrates and invertebrates and can have properties both of a hormone and a neurotransmitter and acts as an adrenergic agonist. GO:0004988 obsolete mu-opioid receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004988 Wikipedia:Mu_Opioid_receptor mu-opioid receptor activity OBSOLETE. Combining with an opioid to initiate a change in cell activity, with the pharmacological characteristics of mu-opioid receptors, including high affinity for enkephalins and beta-endorphin but low affinity for dynorphins. GO:0004983 neuropeptide Y receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004983 Combining with neuropeptide Y to initiate a change in cell activity. GO:0004982 N-formyl peptide receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004982 Fmet-leu-phe receptor Combining with an N-formyl peptide to initiate a change in cell activity. GO:0004985 opioid receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004985 Combining with an opioid (any narcotic derived from or resembling opium), and transmitting the signal across the membrane by activating an associated G-protein. GO:0004984 olfactory receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004984 odorant receptor activity Combining with an odorant and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity in response to detection of smell. GO:0004981 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004981 GO:0004980 melanocyte-stimulating hormone receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004980 MSH receptor activity|melanocyte stimulating hormone receptor activity|melanophore-stimulating hormone receptor activity|MSHR activity Combining with melanocyte-stimulating hormone to initiate a change in cell activity. CHEBI:77472 1-octadecylglycerone 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77472 CHEBI:77471 1-heptadecylglycerone 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77471 CHEBI:77470 heptadecan-1-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77470 PR:000001004 CD4 molecule biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001004 T-cell surface glycoprotein CD4|T-cell surface antigen T4/Leu-3|T-cell differentiation antigen L3T4|CD4 A protein that is a translation product of the human CD4 gene or a 1:1 ortholog thereof. CD4 is an accessory protein for MHC class-II antigen/T-cell receptor interaction. It is the primary receptor for HIV-1. CD4 has four immunoglobulin-like domains in its extracellular region that share the same structure, but can differ in sequence. CHEBI:77475 1-(9Z,12Z,15Z)-octadecatrienylglycerone 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77475 CHEBI:77474 (9Z,12Z,15Z)-octadecatrien-1-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77474 CHEBI:77473 1-(9Z,12Z)-octadecadienylglycerone 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77473 CHEBI:53460 all-cis-icosa-11,14,17-trienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53460 CHEBI:53463 heptasaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53463 GO:0004998 transferrin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004998 Combining selectively with transferrin, and delivering transferrin into the cell via endocytosis. Transferrin is a major iron carrier protein in vertebrates. GO:0004997 thyrotropin-releasing hormone receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004997 Combining with thyrotropin-releasing hormone to initiate a change in cell activity. GO:0004999 vasoactive intestinal polypeptide receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004999 Combining with vasoactive intestinal polypeptide to initiate a change in cell activity. GO:0004994 somatostatin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004994 SRIF receptor activity|SST receptor activity|growth hormone-inhibiting hormone receptor activity|GHIH receptor activity|somatotrophin release inhibiting factor receptor activity Combining with somatostatin to initiate a change in cell activity. Somatostatin is a peptide hormone that regulates the endocrine system by signaling via G protein-coupled somatostatin receptors. Somatostatin has two active forms produced by proteolytic cleavage: a 14 amino acid peptide (SST-14) and a 28 amino acid peptide (SST-28). GO:0004993 G protein-coupled serotonin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004993 Wikipedia:5-HT_receptor 5-HT receptor|5-hydroxytryptamine receptor|G protein coupled serotonin receptor activity|G-protein coupled serotonin receptor activity Combining with the biogenic amine serotonin and transmitting the signal across the membrane by activating an associated G-protein. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates. GO:0004996 thyroid-stimulating hormone receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004996 Wikipedia:Thyrotropin_receptor TSH receptor activity|thyrotropin receptor|thyroid stimulating hormone receptor activity Combining with thyroid-stimulating hormone to initiate a change in cell activity. GO:0004995 tachykinin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004995 Combining with a tachykinin neuropeptide and transmitting the signal across the membrane by activating an associated G-protein. GO:0004990 oxytocin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004990 Combining with oxytocin to initiate a change in cell activity. GO:0004992 platelet activating factor receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004992 PAF receptor activity Combining with platelet activating factor to initiate a change in cell activity. GO:0004991 parathyroid hormone receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004991 Combining with parathyroid hormone to initiate a change in cell activity. CHEBI:77483 (4R)-4-hydroxy-L-lysine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77483 CHEBI:77482 (3S)-3-hydroxy-L-lysine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77482 CHEBI:77484 EC 1.1.1.25 (shikimate dehydrogenase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77484 CHEBI:53455 D-xylopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_53455 CHEBI:77488 (3S)-3-hydroxy-L-ornithine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77488 GO:0004965 G protein-coupled GABA receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004965 Reactome:R-HSA-1013013|Reactome:R-HSA-1013012 GABA-B receptor activity|G-protein coupled GABA receptor activity|metabotropic GABA receptor Combining with the amino acid gamma-aminobutyric acid (GABA, 4-aminobutyrate) and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. GO:0004964 luteinizing hormone receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004964 LH receptor|LHR|lutropin receptor|lutropin-choriogonadotropic hormone receptor Combining with luteinizing hormone (also called lutropin) to initiate a change in cell activity. GO:0004967 glucagon receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004967 Combining with glucagon and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. GO:0004966 galanin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004966 Combining with galanin to initiate a change in cell activity. GO:0004961 thromboxane A2 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004961 TXA2 receptor activity|TXA(2) receptor activity Combining with thromboxane A2 (TXA(2)) and transmitting the signal across the membrane to activate an associated G-protein. GO:0004960 thromboxane receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004960 TXA receptor activity Combining with a thromboxane (TXA) to initiate a change in cell activity. GO:0004963 follicle-stimulating hormone receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004963 FSH receptor activity|follicle stimulating hormone receptor activity Combining with follicle-stimulating hormone to initiate a change in cell activity. GO:0004962 endothelin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004962 endothelin-B receptor activity|endothelin-A receptor activity Combining with endothelin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. CHEBI:28488 m-xylene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28488 CHEBI:28484 isovaleric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28484 CHEBI:28490 L-methionine sulfoximine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28490 UBERON:0011823 dense connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011823 Dense connective tissue is mainly composed of collagen type I. Crowded between the collagen fibers are rows of fibroblasts, fiber-forming cells, that manufacture the fibers. Dense connective tissue forms strong, rope-like structures such as tendons and ligaments. Tendons attach skeletal muscles to bones; ligaments connect bones to bones at joints. Ligaments are more stretchy and contain more elastic fibers than tendons. Dense connective tissue also make up the lower layers of the skin (dermis), where it is arranged in sheets UBERON:0011822 dense irregular connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011822 typus irregularis (textus connectivus collagenosus compactus)|irregular dense connective tissue Irregular connective tissue is an irregular connective tissue, the intercellular matrix of which contains a dense irregular network of collagen and elastic fiber bundles. Examples: connective tissue of peritoneum, connective tissue of fibrous pericardium. UBERON:0011821 irregular connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011821 Connective tissue, which consists of a population of connective tissue cells, the intercellular matrix of which contains an irregular network of collagen and elastic fiber bundles. Examples: areolar tissue, mucoid tissue, connective tissue of peritoneum, connective tissue of fibrous pericardium. CHEBI:28492 5-methylbarbituric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28492 UBERON:0011820 atrioventricular region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011820 AV segment|atrial ventricular junction|AV region|atrioventricular junction|atrioventricular segment An anatomical junction that divides and overlaps with and atrium and a ventricle in the heart. CHEBI:77494 1-arachidonoylglycerone 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77494 CHEBI:77493 1-linoleoylglycerone 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77493 CHEBI:77492 1-oleoylglycerone 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77492 UBERON:0011825 loose connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011825 textus connectivus laxus|textus connectivus collagenosus laxus Irregular connective tissue, the intercellular matrix of which contains a sparse irregular network of collagen and elastic fiber bundles. Examples: areolar tissue, neuroglial tissue, mucoid tissue. UBERON:0011824 fibrous connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011824 CHEBI:77497 (16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77497 GO:0004969 histamine receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004969 Combining with histamine to initiate a change in cell activity. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. GO:0004968 gonadotropin-releasing hormone receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004968 GnRH receptor activity|gonadotrophin-releasing hormone receptor activity Combining with gonadotropin-releasing hormone to initiate a change in cell activity. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus. CHEBI:77499 (21Z,24Z,27Z,30Z,33Z)-hexatriacontapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77499 GO:0004976 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004976 GO:0004975 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004975 GO:0004978 corticotropin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004978 adrenocorticotropic hormone receptor activity|ACTH receptor activity|adrenocorticotropin receptor activity Combining with corticotropin to initiate a change in cell activity. GO:0004977 melanocortin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004977 Combining with melanocortin to initiate a change in cell activity. GO:0004972 NMDA glutamate receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004972 Wikipedia:NMDA_receptor N-methyl-D-aspartate selective glutamate receptor activity|NMDA receptor An cation channel that opens in response to binding by extracellular glutmate, but only if glycine is also bound and the membrane is depolarized. Voltage gating is indirect, due to ejection of bound magnesium from the pore at permissive voltages. GO:0004971 AMPA glutamate receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004971 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|AMPA receptor activity An ionotropic glutamate receptor activity that exhibits fast gating by glutamate and acts by opening a cation channel permeable to sodium, potassium, and, in the absence of a GluR2 subunit, calcium. GO:0004974 leukotriene receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004974 Combining with a leukotriene to initiate a change in cell activity. Leukotrienes are pharmacologically active substances with a set of three conjugated double bonds; some contain a peptide group based on cysteine. GO:0004973 obsolete N-methyl-D-aspartate receptor-associated protein activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004973 N-methyl-D-aspartate receptor-associated protein activity OBSOLETE. (Was not defined before being made obsolete). CHEBI:28498 acadesine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28498 CHEBI:28497 N-acetyl-beta-D-galactosamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28497 GO:0004970 ionotropic glutamate receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004970 Catalysis of the transmembrane transfer of an ion by a channel that opens when glutamate has been bound by the channel complex or one of its constituent parts. CHEBI:28499 kaempferol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28499 CHEBI:28494 cardiolipin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28494 CHEBI:28493 decanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28493 CHEBI:28496 N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28496 UBERON:0011814 non-neurogenic ectodermal placode biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011814 Ectodermal placode that does not develop into a component of the nervous system. UBERON:0011819 lumen of atrioventricular canal biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011819 AVC lumen|lumen of AVC|cavity of atrioventricular canal A tube lumen that is part of a atrioventricular canal. CHEBI:53431 chain carrier biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53431 UBERON:0011817 skin appendage placode biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011817 cutaneous appendage follicle placode|skin follicle placode An ectodermal placode that gives rise to any of the cutaneous appendages that protrude from the skin epidermis (heair, feathers, epidermal scales). GO:0004979 beta-endorphin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004979 mu-opioid receptor activity Combining with beta-endorphin, and transmitting the signal across the membrane by activating an associated G-protein. Beta-endorphin is a peptide, 31 amino acids long, resulting from processing of the precursor proopiomelanocortin (POMC). GO:0004943 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004943 GO:0004942 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004942 GO:0004945 angiotensin type II receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004945 An angiotensin receptor activity that acts via Gi protein coupling and cGMP (NO) generation, and may also act via additional signaling mechanisms. GO:0004944 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004944 CHEBI:28469 4-(hydroxyamino)quinoline N-oxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28469 CHEBI:28468 1-O-palmitoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28468 GO:0004941 beta2-adrenergic receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004941 beta2 adrenoceptor Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta2-adrenergic receptors. GO:0004940 beta1-adrenergic receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004940 beta1 adrenoceptor Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta1-adrenergic receptors. CHEBI:28465 acetaldehyde oxime biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28465 CHEBI:28464 4-hydroxy-6-methylpretetramide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28464 CHEBI:28461 4-amino-4-de(dimethylamino)anhydrotetracycline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28461 CHEBI:28460 maltotetraose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28460 CHEBI:28462 ajmaline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28462 CHEBI:28470 3,5-dihydro-4H-imidazol-4-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28470 GO:0004947 bradykinin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004947 Combining with bradykinin to initiate a change in cell activity. GO:0004946 bombesin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004946 Combining with bombesin to initiate a change in cell activity. GO:0004949 cannabinoid receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004949 cannaboid receptor|endocannabinoid receptor activity Combining with a cannabinoid to initiate a change in cell activity. Cannabinoids are a class of diverse chemical compounds that include the endocannabinoids and the phytocannabinoids. GO:0004948 calcitonin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004948 Combining with calcitonin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. GO:0004954 prostanoid receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004954 Combining with a prostanoid, any compound based on or derived from the prostanoate structure, to initiate a change in cell activity. GO:0004953 icosanoid receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004953 eicosanoid receptor activity Combining with an icosanoid to initiate a change in cell activity. GO:0004956 prostaglandin D receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004956 PGD receptor activity|PGD(2) receptor activity Combining with prostaglandin D (PGD(2)) to initiate a change in cell activity. GO:0004955 prostaglandin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004955 Combining with a prostaglandin (PG) to initiate a change in cell activity. GO:0004950 chemokine receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004950 Combining with a chemokine, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria. CHEBI:28479 D-tyrosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28479 GO:0004952 dopamine neurotransmitter receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004952 Combining with the neurotransmitter dopamine to initiate a change in cell activity. GO:0004951 cholecystokinin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004951 CCK receptor activity Combining with cholecystokinin and transmitting the signal across the membrane by activating an associated G-protein to initiate a change in cell activity. Cholecystokinin can act as a neuropeptide or as a gastrointestinal hormone. CHEBI:28478 (2-hydroxyphenyl)acetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28478 CHEBI:28477 7alpha,12alpha-dihydroxycholest-4-en-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28477 CHEBI:28471 alpha-D-GalNAc-(1->3)-[alpha-L-Fuc-(1->2)]-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1->1')-Cer biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28471 GO:1903100 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903100 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolism The chemical reactions and pathways involving 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate. CHEBI:28480 aldehydo-L-lyxose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28480 GO:0004958 prostaglandin F receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004958 PGF receptor activity|PGF(2-alpha) receptor activity Combining with prostaglandin F (PGF (2-alpha)) to initiate a change in cell activity. GO:0004957 prostaglandin E receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004957 PGE(2) receptor activity|PGE receptor activity Combining with prostaglandin E (PGE(2)) to initiate a change in cell activity. GO:0004959 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004959 CHEBI:133050 N-tetradecanoylglycyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133050 CHEBI:133063 N(alpha)-acetyl-L-methionyl-L-aspartyl(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133063 CHEBI:133039 1-(2-aminophenyl)decane-1,3-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133039 CHEBI:77404 (19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77404 CHEBI:77409 (3S)-3-hydroxy-L-lysine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77409 CHEBI:133045 L-methionyl-L-aspartyl zwitterionic residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133045 CHEBI:133042 L-leucyl-L-aspartyl zwitterionic residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133042 CHEBI:77403 (14Z,17Z,20Z,23Z,26Z,29Z)-dotriacontahexaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77403 CHEBI:133041 L-leucyl-L-glutamyl zwitterionic residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133041 CHEBI:133044 L-leucyl-L-arginyl(2+) group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133044 CHEBI:133043 L-leucyl-L-lysyl(2+) group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133043 CHEBI:77400 2-aminopentanenitrile biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77400 CHEBI:77417 tetradecan-1-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77417 CHEBI:133012 5a,11a-dehydrooxytetracycline zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133012 CHEBI:77410 (4R)-4-hydroxy-L-lysine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77410 CHEBI:133011 oxytetracycline zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133011 CHEBI:77411 (3S)-3-hydroxy-L-ornithine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77411 CHEBI:77429 1-palmitylglycerone 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77429 CHEBI:77427 (3R)-3-carboxy-3-hydroxypropanoyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77427 PO:0005849 primary xylem biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0005849 一次木部 (Japanese, exact)|portion of primary xylem tissue (exact)|xilema primario (Spanish, exact) A portion of xylem (PO:0005352) tissue that develops from the procambium (PO:0025275). CHEBI:133029 S-octanoyl-L-cysteine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133029 CHEBI:77425 EC 1.1.1.188 (prostaglandin-F synthase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77425 CHEBI:857 2,2'-iminodipropanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_857 CHEBI:519567 2'-O-methylisoliquiritigenin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_519567 CHEBI:133004 bisbenzylisoquinoline alkaloid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133004 CHEBI:133000 pregnenolone sulfate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133000 CHEBI:77444 1-undecene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77444 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903069 regulation of ERAD|regulation of ER-associated protein degradation|regulation of ER-associated protein catabolism|regulation of ER-associated protein breakdown|regulation of endoplasmic reticulum-associated protein catabolic process|regulation of endoplasmic reticulum-associated protein catabolism|regulation of ER-associated protein catabolic process Any process that modulates the frequency, rate or extent of ER-associated ubiquitin-dependent protein catabolic process. GO:1903068 positive regulation of protein localization to cell tip biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903068 up regulation of protein localization to cell tip|upregulation of protein localisation to cell tip|upregulation of protein localization to cell tip|up-regulation of protein localisation to cell tip|activation of protein localisation to cell tip|up-regulation of protein localization to cell tip|activation of protein localization to cell tip|positive regulation of protein localisation to cell tip|up regulation of protein localisation to cell tip Any process that activates or increases the frequency, rate or extent of protein localization to cell tip. GO:1903078 positive regulation of protein localization to plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903078 positive regulation of protein localisation in plasma membrane|activation of protein localisation in plasma membrane|activation of protein-plasma membrane targeting|up regulation of protein localization to plasma membrane|activation of protein targeting to plasma membrane|positive regulation of protein targeting to plasma membrane|activation of protein localization to plasma membrane|up-regulation of protein localization in plasma membrane|up regulation of protein-plasma membrane targeting|positive regulation of establishment of protein localization to plasma membrane|positive regulation of establishment of protein localisation in plasma membrane|positive regulation of protein-plasma membrane targeting|up-regulation of protein targeting to plasma membrane|up-regulation of protein localisation in plasma membrane|upregulation of protein localization in plasma membrane|up-regulation of protein localization to plasma membrane|up-regulation of protein-plasma membrane targeting|up regulation of protein targeting to plasma membrane|upregulation of protein localisation in plasma membrane|upregulation of protein localization to plasma membrane|up regulation of protein localization in plasma membrane|activation of protein localization in plasma membrane|positive regulation of protein localization in plasma membrane|upregulation of protein-plasma membrane targeting|upregulation of protein targeting to plasma membrane|up regulation of protein localisation in plasma membrane Any process that activates or increases the frequency, rate or extent of protein localization to plasma membrane. GO:1903077 negative regulation of protein localization to plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903077 negative regulation of establishment of protein localization to plasma membrane|downregulation of protein-plasma membrane targeting|negative regulation of establishment of protein localisation in plasma membrane|inhibition of protein localization in plasma membrane|down-regulation of protein localisation in plasma membrane|down-regulation of protein localization to plasma membrane|negative regulation of protein localisation in plasma membrane|negative regulation of protein-plasma membrane targeting|down-regulation of protein-plasma membrane targeting|inhibition of protein localisation in plasma membrane|inhibition of protein-plasma membrane targeting|inhibition of protein localization to plasma membrane|down-regulation of protein targeting to plasma membrane|down regulation of protein localization in plasma membrane|downregulation of protein localization in plasma membrane|negative regulation of establishment of protein localization in plasma membrane|inhibition of protein targeting to plasma membrane|down regulation of protein localisation in plasma membrane|downregulation of protein targeting to plasma membrane|down regulation of protein localization to plasma membrane|downregulation of protein localisation in plasma membrane|down regulation of protein targeting to plasma membrane|down-regulation of protein localization in plasma membrane|negative regulation of protein localization in plasma membrane|down regulation of protein-plasma membrane targeting|negative regulation of protein targeting to plasma membrane|downregulation of protein localization to plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to plasma membrane. GO:1903076 regulation of protein localization to plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903076 regulation of establishment of protein localization in plasma membrane|regulation of protein targeting to plasma membrane|regulation of establishment of protein localization to plasma membrane|regulation of establishment of protein localisation in plasma membrane|regulation of protein localization in plasma membrane|regulation of protein localisation in plasma membrane|regulation of protein-plasma membrane targeting Any process that modulates the frequency, rate or extent of protein localization to plasma membrane. GO:1903075 pyridoxine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903075 pyridoxine import into cell The directed movement of pyridoxine from outside of a cell, across the plasma membrane and into the cytosol. GO:1903074 TRAIL death-inducing signaling complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903074 TRAIL DISC assembly|TRAIL death-inducing signalling complex formation|TRAIL death-inducing signaling complex formation|TRAIL death-inducing signalling complex assembly|TRAIL DISC formation The aggregation, arrangement and bonding together of a set of components to form a TRAIL death-inducing signaling complex. GO:1903073 negative regulation of death-inducing signaling complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903073 down regulation of death-inducing signaling complex assembly|down regulation of death domain-mediated complex assembly involved in extrinsic apoptotic pathway|downregulation of DISC assembly|downregulation of death-inducing signalling complex assembly|down regulation of death domain-mediated complex assembly|downregulation of DISC formation|inhibition of death domain-mediated complex assembly involved in extrinsic apoptotic pathway|down regulation of death-inducing signaling complex formation|downregulation of death-inducing signaling complex assembly|inhibition of death domain-mediated complex assembly|inhibition of death-inducing signaling complex formation|down-regulation of DD-mediated complex assembly|negative regulation of DD-mediated complex assembly|down regulation of DISC formation|down regulation of death-inducing signalling complex assembly|inhibition of death-inducing signalling complex assembly|inhibition of DISC formation|negative regulation of DISC assembly|down-regulation of DISC assembly|down-regulation of death-inducing signaling complex assembly|downregulation of DD-mediated complex assembly|inhibition of DISC assembly|down regulation of DD-mediated complex assembly|negative regulation of death domain-mediated complex assembly involved in extrinsic apoptotic pathway|down-regulation of death domain-mediated complex assembly involved in extrinsic apoptotic pathway|inhibition of DD-mediated complex assembly|inhibition of death-inducing signaling complex assembly|negative regulation of death domain-mediated complex assembly|down-regulation of death domain-mediated complex assembly|down-regulation of death-inducing signaling complex formation|negative regulation of death-inducing signaling complex formation|down-regulation of DISC formation|down-regulation of death-inducing signalling complex assembly|negative regulation of DISC formation|negative regulation of death-inducing signalling complex assembly|downregulation of death domain-mediated complex assembly involved in extrinsic apoptotic pathway|down regulation of DISC assembly|downregulation of death domain-mediated complex assembly|downregulation of death-inducing signaling complex formation Any process that stops, prevents or reduces the frequency, rate or extent of death-inducing signaling complex assembly. GO:1903072 regulation of death-inducing signaling complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903072 regulation of death-inducing signaling complex formation|regulation of death-inducing signalling complex assembly|regulation of DISC formation|regulation of DD-mediated complex assembly|regulation of death domain-mediated complex assembly involved in extrinsic apoptotic pathway|regulation of DISC assembly|regulation of death domain-mediated complex assembly Any process that modulates the frequency, rate or extent of death-inducing signaling complex assembly. GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903071 upregulation of ER-associated protein breakdown|up regulation of endoplasmic reticulum-associated protein catabolic process|upregulation of ER-associated ubiquitin-dependent protein catabolic process|upregulation of endoplasmic reticulum-associated protein catabolism|upregulation of ER-associated protein catabolic process|up regulation of ER-associated protein degradation|up-regulation of ERAD|activation of ER-associated protein degradation|positive regulation of ER-associated protein degradation|upregulation of ER-associated protein catabolism|activation of ERAD|up regulation of ER-associated protein breakdown|upregulation of endoplasmic reticulum-associated protein catabolic process|positive regulation of ER-associated protein breakdown|activation of ER-associated protein breakdown|up regulation of ER-associated ubiquitin-dependent protein catabolic process|up regulation of endoplasmic reticulum-associated protein catabolism|positive regulation of endoplasmic reticulum-associated protein catabolism|activation of ER-associated ubiquitin-dependent protein catabolic process|up regulation of ER-associated protein catabolic process|activation of endoplasmic reticulum-associated protein catabolism|positive regulation of ER-associated protein catabolic process|activation of ER-associated protein catabolic process|up-regulation of ER-associated protein catabolism|activation of ER-associated protein catabolism|positive regulation of ERAD|up-regulation of ER-associated protein degradation|up-regulation of endoplasmic reticulum-associated protein catabolic process|activation of endoplasmic reticulum-associated protein catabolic process|up regulation of ERAD|up-regulation of ER-associated protein breakdown|up-regulation of endoplasmic reticulum-associated protein catabolism|up-regulation of ER-associated ubiquitin-dependent protein catabolic process|up-regulation of ER-associated protein catabolic process|upregulation of ER-associated protein degradation|positive regulation of ER-associated protein catabolism|positive regulation of endoplasmic reticulum-associated protein catabolic process|up regulation of ER-associated protein catabolism|upregulation of ERAD Any process that activates or increases the frequency, rate or extent of ER-associated ubiquitin-dependent protein catabolic process. GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903070 downregulation of ER-associated protein catabolism|downregulation of ER-associated protein degradation|down regulation of ER-associated protein breakdown|downregulation of endoplasmic reticulum-associated protein catabolic process|down regulation of ER-associated ubiquitin-dependent protein catabolic process|down regulation of ER-associated protein catabolism|down regulation of endoplasmic reticulum-associated protein catabolism|inhibition of ER-associated protein catabolism|down regulation of ER-associated protein catabolic process|down regulation of endoplasmic reticulum-associated protein catabolic process|downregulation of ER-associated protein breakdown|inhibition of endoplasmic reticulum-associated protein catabolic process|downregulation of ER-associated ubiquitin-dependent protein catabolic process|downregulation of endoplasmic reticulum-associated protein catabolism|negative regulation of ER-associated protein degradation|down-regulation of ER-associated protein degradation|downregulation of ER-associated protein catabolic process|down-regulation of ERAD|negative regulation of ERAD|down-regulation of ER-associated protein breakdown|negative regulation of ER-associated protein breakdown|inhibition of ER-associated protein degradation|negative regulation of endoplasmic reticulum-associated protein catabolism|down-regulation of ER-associated ubiquitin-dependent protein catabolic process|down-regulation of endoplasmic reticulum-associated protein catabolism|down-regulation of ER-associated protein catabolic process|negative regulation of ER-associated protein catabolic process|inhibition of ER-associated protein breakdown|downregulation of ERAD|inhibition of endoplasmic reticulum-associated protein catabolism|down-regulation of ER-associated protein catabolism|negative regulation of ER-associated protein catabolism|inhibition of ER-associated ubiquitin-dependent protein catabolic process|inhibition of ER-associated protein catabolic process|down-regulation of endoplasmic reticulum-associated protein catabolic process|negative regulation of endoplasmic reticulum-associated protein catabolic process|down regulation of ERAD|inhibition of ERAD|down regulation of ER-associated protein degradation Any process that stops, prevents or reduces the frequency, rate or extent of ER-associated ubiquitin-dependent protein catabolic process. GO:1903079 obsolete negative regulation of protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903079 down-regulation of protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|downregulation of protein localisation to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|down regulation of protein localisation to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|inhibition of protein localisation to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|downregulation of protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|down regulation of protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|inhibition of protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|negative regulation of protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|down-regulation of protein localisation to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|negative regulation of protein localisation to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape OBSOLETE. Any negative regulation of protein localization to cell tip that is involved in positive regulation of establishment of cell polarity regulating cell shape. GO:1903089 5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1903089 acadesine transporter activity Enables the transfer of 5-amino-1-ribofuranosylimidazole-4-carboxamide from one side of a membrane to the other. GO:1903088 5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903088 The process in which 5-amino-1-ribofuranosylimidazole-4-carboxamide is transported across a membrane. GO:1903087 mitotic spindle pole body duplication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903087 spindle pole body biosynthesis involved in mitotic cell cycle|spindle pole body replication involved in mitotic cell cycle|spindle pole body formation involved in mitotic cell cycle|spindle pole body duplication associated with nuclear envelope involved in mitotic cell cycle|spindle pole body biogenesis involved in mitotic cell cycle|spindle pole body duplication in cytoplasm involved in mitotic cell cycle|spindle pole body assembly involved in mitotic cell cycle|spindle pole body duplication involved in mitotic cell cycle Any spindle pole body duplication that is involved in the mitotic cell cycle. GO:1903086 negative regulation of sinapate ester biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903086 downregulation of sinapate ester anabolism|inhibition of sinapate ester biosynthesis|inhibition of sinapate ester biosynthetic process|downregulation of sinapate ester synthesis|down regulation of sinapate ester anabolism|inhibition of sinapate ester anabolism|downregulation of sinapate ester formation|down regulation of sinapate ester synthesis|inhibition of sinapate ester synthesis|down regulation of sinapate ester formation|inhibition of sinapate ester formation|down regulation of sinapate ester biosynthetic process|down regulation of sinapate ester biosynthesis|downregulation of sinapate ester biosynthesis|downregulation of sinapate ester biosynthetic process|down-regulation of sinapate ester anabolism|negative regulation of sinapate ester anabolism|down-regulation of sinapate ester synthesis|negative regulation of sinapate ester biosynthesis|down-regulation of sinapate ester biosynthetic process|negative regulation of sinapate ester synthesis|down-regulation of sinapate ester biosynthesis|down-regulation of sinapate ester formation|negative regulation of sinapate ester formation Any process that stops, prevents or reduces the frequency, rate or extent of sinapate ester biosynthesis. GO:1903085 regulation of sinapate ester biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903085 regulation of sinapate ester anabolism|regulation of sinapate ester synthesis|regulation of sinapate ester formation|regulation of sinapate ester biosynthesis Any process that modulates the frequency, rate or extent of sinapate ester biosynthesis. GO:1903084 protein localization to condensed nuclear chromosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903084 protein localisation in condensed nuclear chromosome|protein localization in condensed nuclear chromosome|protein localisation to condensed nuclear chromosome A process in which a protein is transported to, or maintained in, a location within a condensed nuclear chromosome. GO:1903083 protein localization to condensed chromosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903083 protein localisation in condensed chromosome|protein localization in condensed chromosome|protein localisation to condensed chromosome A process in which a protein is transported to, or maintained in, a location within a condensed chromosome. GO:1903082 positive regulation of C-C chemokine receptor CCR7 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903082 up-regulation of CCR7 signaling pathway|positive regulation of C-C chemokine receptor CCR7 signalling pathway|up regulation of C-C chemokine receptor CCR7 signalling pathway|up regulation of C-C chemokine receptor CCR7 signaling pathway|activation of CCR7 signaling pathway|activation of C-C chemokine receptor CCR7 signaling pathway|positive regulation of CCR7 signaling pathway|up regulation of CCR7 signaling pathway|upregulation of C-C chemokine receptor CCR7 signalling pathway|up-regulation of C-C chemokine receptor CCR7 signaling pathway|activation of C-C chemokine receptor CCR7 signalling pathway|up-regulation of C-C chemokine receptor CCR7 signalling pathway|upregulation of CCR7 signaling pathway|upregulation of C-C chemokine receptor CCR7 signaling pathway Any process that activates or increases the frequency, rate or extent of C-C chemokine receptor CCR7 signaling pathway. GO:1903081 negative regulation of C-C chemokine receptor CCR7 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903081 downregulation of C-C chemokine receptor CCR7 signaling pathway|downregulation of C-C chemokine receptor CCR7 signalling pathway|negative regulation of CCR7 signaling pathway|down-regulation of CCR7 signaling pathway|down regulation of C-C chemokine receptor CCR7 signalling pathway|down-regulation of C-C chemokine receptor CCR7 signaling pathway|inhibition of C-C chemokine receptor CCR7 signalling pathway|downregulation of CCR7 signaling pathway|inhibition of C-C chemokine receptor CCR7 signaling pathway|down regulation of CCR7 signaling pathway|inhibition of CCR7 signaling pathway|down-regulation of C-C chemokine receptor CCR7 signalling pathway|negative regulation of C-C chemokine receptor CCR7 signalling pathway|down regulation of C-C chemokine receptor CCR7 signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of C-C chemokine receptor CCR7 signaling pathway. GO:1903080 regulation of C-C chemokine receptor CCR7 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903080 regulation of C-C chemokine receptor CCR7 signalling pathway|regulation of CCR7 signaling pathway Any process that modulates the frequency, rate or extent of C-C chemokine receptor CCR7 signaling pathway. GO:1903099 positive regulation of CENP-A containing nucleosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903099 up regulation of centromere specific nucleosome exchange|upregulation of centromere-specific nucleosome assembly|up-regulation of CenH3-containing nucleosome assembly at centromere|positive regulation of centromere specific nucleosome exchange|upregulation of DNA replication-independent nucleosome assembly at centromere|up regulation of CENP-A deposition|activation of centromere-specific histone exchange|up-regulation of centromere-specific histone exchange|up-regulation of CENP-A loading|positive regulation of CENP-A deposition|up regulation of CENP-A containing nucleosome assembly at centromere|activation of CenH3-containing nucleosome assembly at centromere|activation of centromere specific nucleosome exchange|activation of CENP-A containing nucleosome assembly at centromere|up-regulation of centromeric DNA replication-independent nucleosome assembly|up regulation of centromere-specific nucleosome assembly|activation of CENP-A loading|activation of CENP-A deposition|activation of centromere-specific nucleosome assembly|positive regulation of CenH3-containing nucleosome assembly at centromere|up-regulation of centromere specific nucleosome exchange|up regulation of DNA replication-independent nucleosome assembly at centromere|positive regulation of centromere-specific nucleosome assembly|activation of DNA replication-independent nucleosome assembly at centromere|up regulation of CenH3-containing nucleosome assembly at centromere|positive regulation of DNA replication-independent nucleosome assembly at centromere|positive regulation of centromere-specific histone exchange|positive regulation of CENP-A loading|upregulation of centromeric DNA replication-independent nucleosome assembly|up-regulation of CENP-A deposition|up regulation of centromere-specific histone exchange|up regulation of CENP-A loading|up-regulation of CENP-A containing nucleosome assembly at centromere|upregulation of centromere specific nucleosome exchange|up-regulation of centromere-specific nucleosome assembly|upregulation of CenH3-containing nucleosome assembly at centromere|up-regulation of DNA replication-independent nucleosome assembly at centromere|upregulation of CENP-A deposition|up regulation of centromeric DNA replication-independent nucleosome assembly|activation of centromeric DNA replication-independent nucleosome assembly|upregulation of centromere-specific histone exchange|positive regulation of centromeric DNA replication-independent nucleosome assembly|upregulation of CENP-A loading|upregulation of CENP-A containing nucleosome assembly at centromere Any process that activates or increases the frequency, rate or extent of the formation of nucleosomes containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres, and the central core in modular centromeres. GO:1903098 negative regulation of CENP-A containing nucleosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903098 down regulation of CENP-A containing nucleosome assembly at centromere|negative regulation of centromeric DNA replication-independent nucleosome assembly|inhibition of CENP-A loading|down-regulation of centromeric DNA replication-independent nucleosome assembly|downregulation of CENP-A deposition|downregulation of CENP-A containing nucleosome assembly at centromere|down regulation of centromere-specific nucleosome assembly|down regulation of DNA replication-independent nucleosome assembly at centromere|down-regulation of centromere specific nucleosome exchange|negative regulation of centromere specific nucleosome exchange|down-regulation of CenH3-containing nucleosome assembly at centromere|negative regulation of CenH3-containing nucleosome assembly at centromere|inhibition of centromeric DNA replication-independent nucleosome assembly|downregulation of centromere-specific nucleosome assembly|downregulation of DNA replication-independent nucleosome assembly at centromere|negative regulation of CENP-A deposition|down-regulation of CENP-A deposition|down-regulation of centromere-specific histone exchange|negative regulation of centromere-specific histone exchange|down-regulation of CENP-A loading|negative regulation of CENP-A loading|down-regulation of CENP-A containing nucleosome assembly at centromere|downregulation of CenH3-containing nucleosome assembly at centromere|down-regulation of centromere-specific nucleosome assembly|negative regulation of centromere-specific nucleosome assembly|inhibition of centromere specific nucleosome exchange|down-regulation of DNA replication-independent nucleosome assembly at centromere|negative regulation of DNA replication-independent nucleosome assembly at centromere|down regulation of centromeric DNA replication-independent nucleosome assembly|inhibition of CENP-A containing nucleosome assembly at centromere|down regulation of CenH3-containing nucleosome assembly at centromere|downregulation of centromere-specific histone exchange|downregulation of CENP-A loading|inhibition of CENP-A deposition|downregulation of centromeric DNA replication-independent nucleosome assembly|inhibition of centromere-specific nucleosome assembly|down regulation of centromere-specific histone exchange|down regulation of centromere specific nucleosome exchange|inhibition of DNA replication-independent nucleosome assembly at centromere|down regulation of CENP-A loading|inhibition of centromere-specific histone exchange|inhibition of CenH3-containing nucleosome assembly at centromere|downregulation of centromere specific nucleosome exchange|down regulation of CENP-A deposition Any process that stops, prevents or reduces the frequency, rate or extent of the formation of nucleosomes containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres, and the central core in modular centromeres. GO:1903097 regulation of CENP-A containing nucleosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903097 regulation of CENP-A deposition|regulation of centromere-specific nucleosome assembly|regulation of DNA replication-independent nucleosome assembly at centromere|regulation of CenH3-containing nucleosome assembly at centromere|regulation of centromeric DNA replication-independent nucleosome assembly|regulation of centromere-specific histone exchange|regulation of CENP-A loading|regulation of centromere specific nucleosome exchange Any process that modulates the rate, frequency or extent of the formation of nucleosomes containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres, and the central core in modular centromeres. GO:1903096 protein localization to meiotic spindle midzone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903096 protein localization in meiotic spindle midzone|protein localisation in meiotic spindle midzone|protein localisation to meiotic spindle midzone A process in which a protein is transported to, or maintained in, a location within a meiotic spindle midzone. GO:1903095 ribonuclease III complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1903095 A protein complex which is capable of ribonuclease III activity. GO:1903094 negative regulation of protein K48-linked deubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903094 down-regulation of protein K48-linked deubiquitination|inhibition of protein K48-linked deubiquitination|down regulation of protein K48-linked deubiquitination|downregulation of protein K48-linked deubiquitination Any process that stops, prevents or reduces the frequency, rate or extent of protein K48-linked deubiquitination. GO:1903093 regulation of protein K48-linked deubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903093 Any process that modulates the frequency, rate or extent of protein K48-linked deubiquitination. GO:1903092 pyridoxine transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903092 The process in which pyridoxine is transported across a membrane. GO:1903091 pyridoxamine transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903091 The process in which pyridoxamine is transported across a membrane. GO:1903090 pyridoxal transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903090 The process in which pyridoxal is transported across a membrane. UBERON:0035881 ethmoidomaxillary suture biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035881 ethmoidomaxillary suture of skull|sutura ethmoidomaxillaris A suture between the orbital surface of the body of the maxilla with the orbital plate of the ethmoid bone. UBERON:0035882 sphenomaxillary suture biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035882 sutura sphenomaxillaris|sphenomaxillary suture of skull an inconstant suture between the pterygoid process of the sphenoid bone and the body of the maxilla. UBERON:0035884 maxillary-premaxillary suture biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035884 premaxillary suture|maxillary-premaxillary incisive suture|incisive suture A suture between the maxilla and premaxilla. CHEBI:133084 prostaglandin G1(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133084 CHEBI:53406 cis-1,4-polyisoprene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_53406 CHEBI:28446 3D-3,5/4-trihydroxycyclohexane-1,2-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28446 CHEBI:53405 poly(isoprene) macromolecule biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_53405 CHEBI:53404 poly(alkylene vinylene) macromolecule biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_53404 CHEBI:28442 15-oxoprostaglandin F2alpha biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28442 UBERON:0011871 nasomaxillary suture biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011871 articulation of the nasal bone with maxilla|nasomaxillary suture of skull A cranial suture that connects a nasal bone and connects a maxilla. UBERON:0011865 corneal stroma collagen fibril biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011865 The connective tissue bundles in the extracellular matrix of corneal stroma that are composed of collagen, and play a role in tissue strength and elasticity UBERON:0011864 tendon collagen fibril biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011864 The connective tissue bundles in the extracellular matrix of tendon tissue that are composed of collagen, and play a role in tissue strength and elasticity CHEBI:28459 D-alpha-glutamyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28459 CHEBI:28453 (20S)-20-hydroxypregn-4-en-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28453 CHEBI:28455 D-arabinitol 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28455 UBERON:0011863 bone collagen fibril biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011863 The connective tissue bundles in the extracellular matrix of bone tissue that are composed of collagen, and play a role in tissue strength and elasticity UBERON:0011862 pulmonary collagen fibril biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011862 The connective tissue bundles in the extracellular matrix of pulmonary tissue that are composed of collagen, and play a role in tissue strength and elasticity UBERON:0011861 aorta collagen fibril biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011861 The connective tissue bundles in the extracellular matrix of aorta tissue that are composed of collagen, and play a role in tissue strength and elasticity UBERON:0011860 collection of collagen fibrils biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011860 GO:1903001 negative regulation of lipid transport across blood-brain barrier biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903001 down-regulation of lipid transport across blood brain barrier|downregulation of lipid transport across blood brain barrier|down regulation of lipid transport across blood brain barrier|inhibition of lipid transport across blood brain barrier|negative regulation of lipid transport across blood brain barrier Any process that stops, prevents or reduces the frequency, rate or extent of lipid transport across blood-brain barrier. UBERON:0011856 acinus of lactiferous gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011856 lactiferous gland acinus An acinus that is part of a mammary gland. GO:1903000 regulation of lipid transport across blood-brain barrier biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903000 regulation of lipid transport across blood brain barrier Any process that modulates the frequency, rate or extent of lipid transport across blood-brain barrier. UBERON:0011858 acinus of exocrine gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011858 exocrine gland acinus An acinus that is part of a exocrine gland. UBERON:0011857 acinus of lacrimal gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011857 lacrimal gland acinus An acinus that is part of a lacrimal gland. CHEBI:28428 beta-hexachlorocyclohexane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28428 CHEBI:28425 alpha-carotene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28425 CHEBI:28424 alpha-Neu5NAc-(2->8)-alpha-Neu5NAc-(2->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28424 CHEBI:28427 arabinoxylan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28427 CHEBI:28426 cyanidin 3-O-beta-D-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28426 GO:1903009 proteasome complex disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903009 proteasome degradation|proteasome disassembly|26S proteasome disassembly The disaggregation of a proteasome complex into its constituent components. GO:1903008 organelle disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903008 organelle degradation The disaggregation of an organelle into its constituent components. CHEBI:28423 6-methoxy-2-octaprenyl-1,4-benzoquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28423 GO:1903007 positive regulation of Lys63-specific deubiquitinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903007 upregulation of Lys63-specific deubiquitinase activity|up-regulation of Lys63-specific deubiquitinase activity|activation of Lys63-specific deubiquitinase activity|up regulation of Lys63-specific deubiquitinase activity Any process that activates or increases the frequency, rate or extent of Lys63-specific deubiquitinase activity. GO:1903006 positive regulation of protein K63-linked deubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903006 up regulation of protein K63-linked deubiquitination|activation of protein K63-linked deubiquitination|up-regulation of protein K63-linked deubiquitination|upregulation of protein K63-linked deubiquitination Any process that activates or increases the frequency, rate or extent of protein K63-linked deubiquitination. CHEBI:28422 3-oxohexanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28422 GO:1903005 negative regulation of protein K63-linked deubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903005 down regulation of protein K63-linked deubiquitination|downregulation of protein K63-linked deubiquitination|down-regulation of protein K63-linked deubiquitination|inhibition of protein K63-linked deubiquitination Any process that stops, prevents or reduces the frequency, rate or extent of protein K63-linked deubiquitination. GO:1903004 regulation of protein K63-linked deubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903004 Any process that modulates the frequency, rate or extent of protein K63-linked deubiquitination. GO:1903003 positive regulation of protein deubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903003 up-regulation of protein deubiquitylation|activation of protein deubiquitylation|up-regulation of protein deubiquitinylation|upregulation of deubiquitination|activation of protein deubiquitinylation|upregulation of protein deubiquitination|positive regulation of protein deubiquitylation|up regulation of protein deubiquitylation|up-regulation of deubiquitination|positive regulation of protein deubiquitinylation|activation of deubiquitination|up-regulation of protein deubiquitination|up regulation of protein deubiquitinylation|activation of protein deubiquitination|upregulation of protein deubiquitylation|positive regulation of deubiquitination|upregulation of protein deubiquitinylation|up regulation of deubiquitination|up regulation of protein deubiquitination Any process that activates or increases the frequency, rate or extent of protein deubiquitination. UBERON:0011850 acinus of salivary gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011850 salivary gland acinus An acinus that is part of a salivary gland. GO:1903002 positive regulation of lipid transport across blood-brain barrier biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903002 positive regulation of lipid transport across blood brain barrier|activation of lipid transport across blood brain barrier|up-regulation of lipid transport across blood brain barrier|up regulation of lipid transport across blood brain barrier|upregulation of lipid transport across blood brain barrier Any process that activates or increases the frequency, rate or extent of lipid transport across blood-brain barrier. GO:1903012 positive regulation of bone development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903012 up-regulation of bone development|activation of bone development|up regulation of bone development|upregulation of bone development Any process that activates or increases the frequency, rate or extent of bone development. UBERON:0011845 duct of sebaceous gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011845 sebaceous gland duct A duct that is part of a sebaceous gland. GO:1903011 negative regulation of bone development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903011 down-regulation of bone development|downregulation of bone development|down regulation of bone development|inhibition of bone development Any process that stops, prevents or reduces the frequency, rate or extent of bone development. GO:1903010 regulation of bone development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903010 Any process that modulates the frequency, rate or extent of bone development. UBERON:0011846 acinus of sebaceous gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011846 sebaceous gland acinus An acinus that is part of a sebaceous gland. CHEBI:7203 N-acetylhexosamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_7203 CHEBI:28436 delphinidin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28436 GO:1903019 negative regulation of glycoprotein metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903019 down-regulation of glycoprotein metabolism|negative regulation of glycoprotein metabolism|down-regulation of glycoprotein metabolic process|inhibition of glycoprotein metabolism|downregulation of glycoprotein metabolic process|down regulation of glycoprotein metabolic process|inhibition of glycoprotein metabolic process|down regulation of glycoprotein metabolism|downregulation of glycoprotein metabolism Any process that stops, prevents or reduces the frequency, rate or extent of glycoprotein metabolic process. GO:1903018 regulation of glycoprotein metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903018 regulation of glycoprotein metabolism Any process that modulates the frequency, rate or extent of glycoprotein metabolic process. GO:1903017 positive regulation of exo-alpha-sialidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903017 upregulation of neuraminidase activity|upregulation of exo-alpha-sialidase activity|upregulation of sialidase activity|positive regulation of alpha-neuraminidase activity|up-regulation of acetylneuraminidase activity|activation of acetylneuraminidase activity|up regulation of acetylneuraminyl hydrolase activity|upregulation of N-acylneuraminate glycohydrolase activity|up regulation of alpha-neuraminidase activity|activation of acetylneuraminyl hydrolase activity|positive regulation of acetylneuraminyl hydrolase activity|up-regulation of neuraminidase activity|activation of neuraminidase activity|up-regulation of exo-alpha-sialidase activity|up-regulation of sialidase activity|activation of sialidase activity|activation of exo-alpha-sialidase activity|positive regulation of acetylneuraminidase activity|upregulation of alpha-neuraminidase activity|up regulation of N-acylneuraminate glycohydrolase activity|up regulation of acetylneuraminidase activity|activation of N-acylneuraminate glycohydrolase activity|up-regulation of acetylneuraminyl hydrolase activity|positive regulation of N-acylneuraminate glycohydrolase activity|positive regulation of neuraminidase activity|up regulation of neuraminidase activity|positive regulation of sialidase activity|up-regulation of alpha-neuraminidase activity|up regulation of exo-alpha-sialidase activity|up regulation of sialidase activity|activation of alpha-neuraminidase activity|upregulation of acetylneuraminidase activity|upregulation of acetylneuraminyl hydrolase activity|up-regulation of N-acylneuraminate glycohydrolase activity Any process that activates or increases the frequency, rate or extent of exo-alpha-sialidase activity. CHEBI:28433 phyllohydroquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28433 GO:1903016 negative regulation of exo-alpha-sialidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903016 negative regulation of alpha-neuraminidase activity|down regulation of exo-alpha-sialidase activity|down-regulation of alpha-neuraminidase activity|down regulation of sialidase activity|inhibition of exo-alpha-sialidase activity|inhibition of sialidase activity|downregulation of acetylneuraminyl hydrolase activity|down regulation of N-acylneuraminate glycohydrolase activity|downregulation of alpha-neuraminidase activity|negative regulation of acetylneuraminidase activity|down-regulation of acetylneuraminidase activity|negative regulation of acetylneuraminyl hydrolase activity|down-regulation of acetylneuraminyl hydrolase activity|downregulation of N-acylneuraminate glycohydrolase activity|down regulation of alpha-neuraminidase activity|inhibition of alpha-neuraminidase activity|negative regulation of neuraminidase activity|down-regulation of neuraminidase activity|inhibition of acetylneuraminyl hydrolase activity|negative regulation of sialidase activity|down-regulation of exo-alpha-sialidase activity|down-regulation of sialidase activity|downregulation of acetylneuraminidase activity|negative regulation of N-acylneuraminate glycohydrolase activity|down-regulation of N-acylneuraminate glycohydrolase activity|downregulation of neuraminidase activity|down regulation of acetylneuraminidase activity|inhibition of acetylneuraminidase activity|downregulation of exo-alpha-sialidase activity|downregulation of sialidase activity|inhibition of N-acylneuraminate glycohydrolase activity|down regulation of neuraminidase activity|inhibition of neuraminidase activity|down regulation of acetylneuraminyl hydrolase activity Any process that stops, prevents or reduces the frequency, rate or extent of exo-alpha-sialidase activity. GO:1903015 regulation of exo-alpha-sialidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903015 regulation of acetylneuraminyl hydrolase activity|regulation of alpha-neuraminidase activity|regulation of N-acylneuraminate glycohydrolase activity|regulation of acetylneuraminidase activity|regulation of neuraminidase activity|regulation of sialidase activity Any process that modulates the frequency, rate or extent of exo-alpha-sialidase activity. GO:1903014 cellular response to differentiation-inducing factor 1 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903014 cellular response to DIF1|cellular response to 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one|cellular response to DIF-1|DIF-1 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one stimulus. GO:1903013 response to differentiation-inducing factor 1 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903013 response to DIF1|DIF-1|response to 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one|response to DIF-1 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one stimulus. GO:1903023 regulation of ascospore-type prospore membrane formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903023 regulation of forespore membrane biosynthesis|regulation of forespore membrane formation|regulation of ascospore-type prospore membrane assembly|regulation of FSM biosynthesis|regulation of FSM formation|regulation of FSM assembly Any process that modulates the frequency, rate or extent of formation of an ascospore-type prospore membrane. GO:1903022 positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903022 upregulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands|up-regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands|activation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands|up regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands Any process that activates or increases the frequency, rate or extent of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands. GO:1903021 regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903021 Any process that modulates the frequency, rate or extent of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands. GO:1903020 positive regulation of glycoprotein metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903020 upregulation of glycoprotein metabolic process|up regulation of glycoprotein metabolism|activation of glycoprotein metabolism|positive regulation of glycoprotein metabolism|up-regulation of glycoprotein metabolic process|activation of glycoprotein metabolic process|up-regulation of glycoprotein metabolism|up regulation of glycoprotein metabolic process|upregulation of glycoprotein metabolism Any process that activates or increases the frequency, rate or extent of glycoprotein metabolic process. CHEBI:28408 4-de(dimethylamino)-4-oxoanhydrotetracycline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28408 CHEBI:28401 N-acetyl-D-glucosaminide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28401 GO:1903028 positive regulation of opsonization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903028 activation of opsonization|up-regulation of opsonization|up regulation of opsonization|upregulation of opsonization Any process that activates or increases the frequency, rate or extent of opsonization. GO:1903027 regulation of opsonization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903027 Any process that modulates the frequency, rate or extent of opsonization. GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903026 down-regulation of RNA polymerase II regulatory region sequence-specific DNA binding|inhibition of RNA polymerase II regulatory region sequence-specific DNA binding|down regulation of RNA polymerase II regulatory region sequence-specific DNA binding|downregulation of RNA polymerase II regulatory region sequence-specific DNA binding Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding. GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903025 Any process that modulates the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding. GO:1903024 positive regulation of ascospore-type prospore membrane formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903024 activation of FSM formation|positive regulation of FSM formation|positive regulation of forespore membrane formation|upregulation of forespore membrane biosynthesis|upregulation of FSM assembly|up regulation of ascospore-type prospore membrane assembly|up regulation of forespore membrane formation|activation of ascospore-type prospore membrane assembly|up-regulation of FSM biosynthesis|activation of FSM biosynthesis|up-regulation of FSM formation|up-regulation of FSM assembly|activation of FSM assembly|up regulation of forespore membrane biosynthesis|upregulation of forespore membrane formation|activation of forespore membrane biosynthesis|positive regulation of forespore membrane biosynthesis|up-regulation of ascospore-type prospore membrane assembly|positive regulation of FSM biosynthesis|up regulation of FSM biosynthesis|upregulation of FSM formation|positive regulation of FSM assembly|up-regulation of forespore membrane formation|activation of forespore membrane formation|up regulation of FSM assembly|up-regulation of forespore membrane biosynthesis|upregulation of ascospore-type prospore membrane assembly|positive regulation of ascospore-type prospore membrane assembly|upregulation of FSM biosynthesis|up regulation of FSM formation Any process that activates or increases the frequency, rate or extent of formation of an ascospore-type prospore membrane. GO:1903034 regulation of response to wounding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903034 regulation of physiological response to wounding Any process that modulates the frequency, rate or extent of response to wounding. GO:1903033 positive regulation of microtubule plus-end binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903033 up-regulation of microtubule plus-end binding|activation of microtubule plus-end binding|up regulation of microtubule plus-end binding|upregulation of microtubule plus-end binding Any process that activates or increases the frequency, rate or extent of microtubule plus-end binding. GO:1903032 negative regulation of microtubule plus-end binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903032 down-regulation of microtubule plus-end binding|downregulation of microtubule plus-end binding|down regulation of microtubule plus-end binding|inhibition of microtubule plus-end binding Any process that stops, prevents or reduces the frequency, rate or extent of microtubule plus-end binding. GO:1903031 regulation of microtubule plus-end binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903031 Any process that modulates the frequency, rate or extent of microtubule plus-end binding. CHEBI:28417 gentamycin C biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28417 CHEBI:28413 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28413 CHEBI:28416 5-hydroxyimidazole-4-acetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28416 GO:1903039 positive regulation of leukocyte cell-cell adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903039 up regulation of leukocyte adhesion|up-regulation of leukocyte cell-cell adhesion|activation of leukocyte cell-cell adhesion|up regulation of leukocyte cell adhesion|activation of leukocyte cell adhesion|positive regulation of leukocyte cell adhesion|upregulation of leukocyte adhesion|up regulation of leukocyte cell-cell adhesion|up-regulation of leukocyte cell adhesion|up-regulation of leukocyte adhesion|activation of leukocyte adhesion|upregulation of leukocyte cell-cell adhesion|upregulation of leukocyte cell adhesion|positive regulation of leukocyte adhesion Any process that activates or increases the frequency, rate or extent of leukocyte cell-cell adhesion. GO:1903038 negative regulation of leukocyte cell-cell adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903038 downregulation of leukocyte cell adhesion|downregulation of leukocyte adhesion|down-regulation of leukocyte cell-cell adhesion|down regulation of leukocyte adhesion|inhibition of leukocyte adhesion|down-regulation of leukocyte cell adhesion|negative regulation of leukocyte cell adhesion|downregulation of leukocyte cell-cell adhesion|inhibition of leukocyte cell adhesion|down regulation of leukocyte cell-cell adhesion|inhibition of leukocyte cell-cell adhesion|negative regulation of leukocyte adhesion|down-regulation of leukocyte adhesion|down regulation of leukocyte cell adhesion Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte cell-cell adhesion. GO:1903037 regulation of leukocyte cell-cell adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903037 regulation of leukocyte adhesion|regulation of leukocyte cell adhesion Any process that modulates the frequency, rate or extent of leukocyte cell-cell adhesion. GO:1903036 positive regulation of response to wounding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903036 upregulation of response to wounding|positive regulation of physiological response to wounding|up regulation of physiological response to wounding|up-regulation of response to wounding|activation of response to wounding|upregulation of physiological response to wounding|up regulation of response to wounding|up-regulation of physiological response to wounding|activation of physiological response to wounding Any process that activates or increases the frequency, rate or extent of response to wounding. GO:1903035 negative regulation of response to wounding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903035 inhibition of response to wounding|down-regulation of physiological response to wounding|negative regulation of physiological response to wounding|downregulation of physiological response to wounding|down regulation of physiological response to wounding|inhibition of physiological response to wounding|down-regulation of response to wounding|downregulation of response to wounding|down regulation of response to wounding Any process that stops, prevents or reduces the frequency, rate or extent of response to wounding. GO:1903045 neural crest cell migration involved in sympathetic nervous system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903045 Any neural crest cell migration that is involved in sympathetic nervous system development. GO:1903044 protein localization to membrane raft biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903044 protein localisation in membrane raft|protein localisation to membrane raft|protein localization in membrane raft A process in which a protein is transported to, or maintained in, a location within a membrane raft. UBERON:0011899 epimysium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011899 fascia of muscle organ|epimysia Epimysium is a layer of connective tissue which ensheaths the entire muscle. It is composed of dense irregular connective tissue. It is continuous with fascia and other connective tissue wrappings of muscle including the endomysium, and perimysium. It is also continuous with tendons where it becomes thicker and collagenous. GO:1903043 positive regulation of chondrocyte hypertrophy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903043 upregulation of chondrocyte hypertrophy|up regulation of chondrocyte hypertrophy|activation of chondrocyte hypertrophy|up-regulation of chondrocyte hypertrophy Any process that activates or increases the frequency, rate or extent of chondrocyte hypertrophy. GO:1903042 negative regulation of chondrocyte hypertrophy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903042 down regulation of chondrocyte hypertrophy|downregulation of chondrocyte hypertrophy|down-regulation of chondrocyte hypertrophy|inhibition of chondrocyte hypertrophy Any process that stops, prevents or reduces the frequency, rate or extent of chondrocyte hypertrophy. GO:1903041 regulation of chondrocyte hypertrophy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903041 Any process that modulates the frequency, rate or extent of chondrocyte hypertrophy. UBERON:0035805 muscle layer of sigmoid colon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035805 sigmoid colon muscularis propria|tunica muscularis colon sigmoideum|muscularis externa of sigmoid colon|sigmoideum muscularis|muscularis propria of sigmoid colon A muscle layer that is part of the sigmoid colon UBERON:0035804 future mouth biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035804 primordial mouth|primitive mouth The primordial mouth region of the developing head. GO:1903040 exon-exon junction complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903040 EJC formation|EJC assembly|exon-exon junction complex formation The aggregation, arrangement and bonding together of a set of components to form an exon-exon junction complex. UBERON:0035809 serous cavity biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035809 CHEBI:7274 N-formimidoyl-L-glutamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_7274 UBERON:0011892 anterior uvea biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011892 anterior vascular tunic of the eye|vasculosa oculi|Haller tunica vascula|anterior part of uveal tract|anterior vascular layer of the eyeball|anterior uveal tract|ciliary body and iris|tunica vasculosa bulbosa|ventral uveal tract Front (ventral) portion of the vascular, pigmentary, or middle coat of the eye, including the ciliary body and the iris. GO:1903049 negative regulation of acetylcholine-gated cation channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903049 down regulation of acetylcholine-gated cation channel activity|downregulation of acetylcholine-gated cation channel activity|down-regulation of acetylcholine-gated cation channel activity|inhibition of acetylcholine-gated cation channel activity Any process that stops, prevents or reduces the frequency, rate or extent of acetylcholine-gated cation channel activity. GO:1903048 regulation of acetylcholine-gated cation channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903048 Any process that modulates the frequency, rate or extent of acetylcholine-gated cation channel activity. GO:1903047 mitotic cell cycle process biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_1903047 A process that is part of the mitotic cell cycle. UBERON:0011894 lumen of vagina biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011894 vaginal lumen A organ cavity that is part of a vagina. GO:1903046 meiotic cell cycle process biolink:BiologicalProcess go-plus goslim_pombe|gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_1903046 A process that is part of the meiotic cell cycle. UBERON:0035820 peritoneal sac biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035820 peritoneal component A serous sac that is the aggregate of the peritoneum and the peritoneal cavity, located in the abdominal cavity. GO:1903056 regulation of melanosome organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903056 regulation of melanosome organization and biogenesis|regulation of melanosome organisation Any process that modulates the frequency, rate or extent of melanosome organization. GO:1903055 positive regulation of extracellular matrix organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903055 upregulation of extracellular matrix organization|up-regulation of extracellular matrix organization and biogenesis|up regulation of extracellular matrix organisation|activation of extracellular matrix organisation|positive regulation of extracellular matrix organisation|activation of extracellular matrix organization and biogenesis|up regulation of extracellular matrix organization|positive regulation of extracellular matrix organization and biogenesis|activation of extracellular matrix organization|up regulation of extracellular matrix organization and biogenesis|up-regulation of extracellular matrix organisation|up-regulation of extracellular matrix organization|upregulation of extracellular matrix organization and biogenesis|upregulation of extracellular matrix organisation Any process that activates or increases the frequency, rate or extent of extracellular matrix organization. GO:1903054 negative regulation of extracellular matrix organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903054 downregulation of extracellular matrix organisation|down regulation of extracellular matrix organization|downregulation of extracellular matrix organization|negative regulation of extracellular matrix organization and biogenesis|down-regulation of extracellular matrix organization and biogenesis|negative regulation of extracellular matrix organisation|down-regulation of extracellular matrix organisation|down-regulation of extracellular matrix organization|inhibition of extracellular matrix organisation|downregulation of extracellular matrix organization and biogenesis|down regulation of extracellular matrix organization and biogenesis|inhibition of extracellular matrix organization|inhibition of extracellular matrix organization and biogenesis|down regulation of extracellular matrix organisation Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix organization. UBERON:0035814 pericardial fat biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035814 The sum of epicardial and paracardial fat deposits. GO:1903053 regulation of extracellular matrix organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903053 regulation of extracellular matrix organisation|regulation of extracellular matrix organization and biogenesis Any process that modulates the frequency, rate or extent of extracellular matrix organization. GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903052 up regulation of peptidolysis involved in cellular protein catabolic process|up-regulation of proteolysis during cellular protein catabolic process|activation of proteolysis during cellular protein catabolism|up-regulation of peptidolysis during cellular protein catabolic process|activation of peptidolysis involved in cellular protein catabolic process|positive regulation of peptidolysis involved in cellular protein catabolic process|upregulation of peptidolysis during cellular protein catabolism|upregulation of proteolysis involved in cellular protein catabolic process|up-regulation of peptidolysis involved in cellular protein catabolism|positive regulation of proteolysis during cellular protein catabolism|activation of peptidolysis involved in cellular protein catabolism|activation of peptidolysis during cellular protein catabolic process|up regulation of proteolysis during cellular protein catabolism|upregulation of proteolysis during cellular protein catabolic process|positive regulation of peptidolysis during cellular protein catabolic process|up-regulation of proteolysis involved in cellular protein catabolic process|up-regulation of peptidolysis involved in cellular protein catabolic process|up regulation of peptidolysis during cellular protein catabolism|activation of proteolysis involved in cellular protein catabolic process|up regulation of peptidolysis during cellular protein catabolic process|positive regulation of peptidolysis during cellular protein catabolism|positive regulation of peptidolysis involved in cellular protein catabolism|upregulation of proteolysis during cellular protein catabolism|up regulation of peptidolysis involved in cellular protein catabolism|up regulation of proteolysis during cellular protein catabolic process|activation of peptidolysis during cellular protein catabolism|upregulation of peptidolysis involved in cellular protein catabolic process|positive regulation of proteolysis during cellular protein catabolic process|upregulation of peptidolysis during cellular protein catabolic process|up regulation of proteolysis involved in cellular protein catabolic process|up-regulation of proteolysis during cellular protein catabolism|activation of proteolysis during cellular protein catabolic process|up-regulation of peptidolysis during cellular protein catabolism|upregulation of peptidolysis involved in cellular protein catabolism Any process that activates or increases the frequency, rate or extent of proteolysis involved in cellular protein catabolic process. GO:1903051 negative regulation of proteolysis involved in cellular protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903051 inhibition of peptidolysis during cellular protein catabolism|down regulation of proteolysis involved in cellular protein catabolic process|inhibition of proteolysis involved in cellular protein catabolic process|negative regulation of proteolysis during cellular protein catabolism|down-regulation of proteolysis during cellular protein catabolism|negative regulation of peptidolysis involved in cellular protein catabolic process|down-regulation of peptidolysis involved in cellular protein catabolic process|inhibition of proteolysis during cellular protein catabolic process|down regulation of peptidolysis during cellular protein catabolism|negative regulation of peptidolysis during cellular protein catabolic process|down-regulation of peptidolysis during cellular protein catabolic process|downregulation of proteolysis during cellular protein catabolism|downregulation of peptidolysis during cellular protein catabolism|down-regulation of peptidolysis involved in cellular protein catabolism|negative regulation of peptidolysis involved in cellular protein catabolism|inhibition of peptidolysis involved in cellular protein catabolic process|down regulation of proteolysis during cellular protein catabolic process|down regulation of proteolysis during cellular protein catabolism|downregulation of proteolysis during cellular protein catabolic process|downregulation of peptidolysis during cellular protein catabolic process|down-regulation of peptidolysis during cellular protein catabolism|negative regulation of peptidolysis during cellular protein catabolism|down-regulation of proteolysis involved in cellular protein catabolic process|downregulation of peptidolysis involved in cellular protein catabolism|down regulation of peptidolysis during cellular protein catabolic process|inhibition of proteolysis during cellular protein catabolism|down regulation of peptidolysis involved in cellular protein catabolism|down regulation of peptidolysis involved in cellular protein catabolic process|inhibition of peptidolysis involved in cellular protein catabolism|negative regulation of proteolysis during cellular protein catabolic process|down-regulation of proteolysis during cellular protein catabolic process|inhibition of peptidolysis during cellular protein catabolic process|downregulation of peptidolysis involved in cellular protein catabolic process|downregulation of proteolysis involved in cellular protein catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of proteolysis involved in cellular protein catabolic process. UBERON:0035815 paracardial fat biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035815 intrathoracic fat Fat deposits in the mediastinum outside the parietal pericardium . GO:1903050 regulation of proteolysis involved in cellular protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903050 regulation of peptidolysis during cellular protein catabolism|regulation of proteolysis during cellular protein catabolism|regulation of proteolysis during cellular protein catabolic process|regulation of peptidolysis during cellular protein catabolic process|regulation of peptidolysis involved in cellular protein catabolism|regulation of peptidolysis involved in cellular protein catabolic process Any process that modulates the frequency, rate or extent of proteolysis involved in cellular protein catabolic process. UBERON:0035818 visceral fat biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035818 Any fat deposit surrounding a visceral organ. UBERON:0035819 abdominopelvic cavity biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035819 cavitas abdominis et pelvis The part of the ventral body cavity that is within the abdominal segment of the trunk, which encompasses the abdomen proper plus pelvic cavity. OBO:cl#has_low_plasma_membrane_amount has_low_plasma_membrane_amount biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/cl#has_low_plasma_membrane_amount has_low_plasma_membrane_amount A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617). GO:1903059 regulation of protein lipidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903059 regulation of lipid:protein modification|regulation of protein amino acid lipidation Any process that modulates the frequency, rate or extent of protein lipidation. GO:1903058 positive regulation of melanosome organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903058 upregulation of melanosome organization|upregulation of melanosome organization and biogenesis|up regulation of melanosome organisation|positive regulation of melanosome organisation|activation of melanosome organisation|up regulation of melanosome organization|up-regulation of melanosome organization and biogenesis|activation of melanosome organization|up-regulation of melanosome organisation|activation of melanosome organization and biogenesis|positive regulation of melanosome organization and biogenesis|up-regulation of melanosome organization|up regulation of melanosome organization and biogenesis|upregulation of melanosome organisation Any process that activates or increases the frequency, rate or extent of melanosome organization. GO:1903057 negative regulation of melanosome organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903057 downregulation of melanosome organisation|down regulation of melanosome organization|inhibition of melanosome organization and biogenesis|downregulation of melanosome organization|down-regulation of melanosome organisation|negative regulation of melanosome organisation|inhibition of melanosome organisation|down-regulation of melanosome organization|down-regulation of melanosome organization and biogenesis|negative regulation of melanosome organization and biogenesis|inhibition of melanosome organization|downregulation of melanosome organization and biogenesis|down regulation of melanosome organisation|down regulation of melanosome organization and biogenesis Any process that stops, prevents or reduces the frequency, rate or extent of melanosome organization. UBERON:0035831 costal diaphragm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035831 costal part of diaphragm|pars costalis diaphragmatis The domain of the diaphragm that is a thin domed sheet of muscle composed of a radial array of myofibers extending laterally from the ribs and medially to a central tendon. GO:1903067 negative regulation of protein localization to cell tip biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903067 down regulation of protein localisation to cell tip|inhibition of protein localisation to cell tip|downregulation of protein localization to cell tip|down regulation of protein localization to cell tip|inhibition of protein localization to cell tip|negative regulation of protein localisation to cell tip|down-regulation of protein localisation to cell tip|down-regulation of protein localization to cell tip|downregulation of protein localisation to cell tip Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell tip. UBERON:0011878 muscle layer of esophagus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011878 tela muscularis (oesophagus)|tunica muscularis oesophageae|muscular layer of oesophagus|muscle coat of esophagus|tunica muscularis esophagi|muscular coat of oesophagus A muscle layer that is part of a wall of esophagus. UBERON:0011877 margin of tongue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011877 tongue margin|margo linguae The lateral border that separates the dorsum from the inferior surface of the tongue on each side, the two borders meeting anteriorly at the apex.. GO:1903066 regulation of protein localization to cell tip biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903066 regulation of protein localisation to cell tip Any process that modulates the frequency, rate or extent of protein localization to cell tip. UBERON:0035825 left adrenal gland cortex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035825 left adrenal cortex|cortex of left suprarenal gland|cortex of left adrenal gland the thick outer layer of the adrenal gland that is in the left side of the abdomen GO:1903065 obsolete protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903065 protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|protein localisation to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape OBSOLETE. Any protein localization to cell tip that is involved in positive regulation of establishment of cell polarity regulating cell shape. GO:1903064 positive regulation of reverse cholesterol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903064 upregulation of reverse cholesterol transport|up regulation of reverse cholesterol transport|activation of reverse cholesterol transport|up-regulation of reverse cholesterol transport Any process that activates or increases the frequency, rate or extent of reverse cholesterol transport. UBERON:0011875 ligament of sternoclavicular joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011875 ligamentum sternoclavicularis|sternoclavicular joint ligament A skeletal ligament that is part of a sternoclavicular joint. UBERON:0035827 right adrenal gland cortex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035827 right adrenal cortex|cortex of right suprarenal gland|cortex of right adrenal gland the thick outer layer of the adrenal gland that is in the right side of the abdomen GO:1903063 negative regulation of reverse cholesterol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903063 down regulation of reverse cholesterol transport|downregulation of reverse cholesterol transport|down-regulation of reverse cholesterol transport|inhibition of reverse cholesterol transport Any process that stops, prevents or reduces the frequency, rate or extent of reverse cholesterol transport. UBERON:0035826 left adrenal gland medulla biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035826 left adrenal medulla|medulla of left adrenal gland|medulla of left suprarenal gland the adrenal gland medulla that is in the left side of the abdomen GO:1903062 regulation of reverse cholesterol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903062 Any process that modulates the frequency, rate or extent of reverse cholesterol transport. GO:1903061 positive regulation of protein lipidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903061 up-regulation of lipid:protein modification|activation of lipid:protein modification|up-regulation of protein lipidation|activation of protein lipidation|up-regulation of protein amino acid lipidation|positive regulation of lipid:protein modification|upregulation of protein amino acid lipidation|up regulation of lipid:protein modification|up regulation of protein lipidation|up regulation of protein amino acid lipidation|upregulation of lipid:protein modification|upregulation of protein lipidation|positive regulation of protein amino acid lipidation|activation of protein amino acid lipidation Any process that activates or increases the frequency, rate or extent of protein lipidation. GO:1903060 negative regulation of protein lipidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1903060 down-regulation of protein amino acid lipidation|negative regulation of protein amino acid lipidation|inhibition of protein amino acid lipidation|negative regulation of lipid:protein modification|down-regulation of lipid:protein modification|down-regulation of protein lipidation|down regulation of protein amino acid lipidation|downregulation of lipid:protein modification|downregulation of protein lipidation|downregulation of protein amino acid lipidation|down regulation of lipid:protein modification|down regulation of protein lipidation|inhibition of lipid:protein modification|inhibition of protein lipidation Any process that stops, prevents or reduces the frequency, rate or extent of protein lipidation. UBERON:0035828 right adrenal gland medulla biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0035828 medulla of right suprarenal gland|right adrenal medulla|medulla of right adrenal gland the adrenal gland medulla that is in the right side of the abdomen PR:000015794 syntaxin-2 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000015794 STX2|epimorphin|EPIM|STX2C|STX2B|STX2A A protein that is a translation product of the human STX2 gene or a 1:1 ortholog thereof. PR:000015795 syntaxin-3 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000015795 STX3|STX3A A protein that is a translation product of the human STX3 gene or a 1:1 ortholog thereof. PR:000015798 syntaxin-6 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000015798 STX6 A protein that is a translation product of the human STX6 gene or a 1:1 ortholog thereof. PR:000015797 syntaxin-5 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000015797 STX5A|STX5 A protein that is a translation product of the human STX5 gene or a 1:1 ortholog thereof. PR:000001150 tachykinin receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001150 A rhodopsin-like G-protein coupled receptor that is a translation product of the human TACR1 to TACR3 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. These receptors bind tachykinin peptides--neuropeptides of 10-12 amino acids derived from the translation products of the TAC1 and TAC3 genes. Tachykinin receptors are not specific but have different affinities for the various peptides. PR:000001141 interleukin-17D biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001141 IL17D|IL-17D|IL-27|IL27|interleukin-27 An interleukin-17 that is a translation product of the human IL17D gene or a 1:1 ortholog thereof. PR:000001146 melanocortin receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001146 A rhodopsin-like G-protein coupled receptor that is a translation product of the human MC1R to MC5R genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds one or more melanocortins, the pituitary peptides ACTH and alpha-, beta-, and gamma-melanocyte-stimulating hormone. CHEBI:77332 saturated fatty acyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77332 CHEBI:77331 monounsaturated fatty acyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77331 CHEBI:53368 ionic macromolecule biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53368 CHEBI:77330 polyunsaturated fatty acyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77330 CHEBI:77349 1,2-dilinoleoyl-sn-glycero-3-phospho-1D-myo-inositol 5-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77349 PR:000001153 Toll-like receptor 2 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001153 CD282|Toll/interleukin-1 receptor-like protein 4|TIL4|TLR2 A Toll-like receptor that is a translation product of the human TLR2 gene or a 1:1 ortholog thereof. PR:000001155 Toll-like receptor 4 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001155 CD284|Lps|TLR4|Toll A Toll-like receptor that is a translation product of the human TLR4 gene or a 1:1 ortholog thereof. CHEBI:133103 (3alpha,5alpha,17beta)-3-hydroxyandrostan-17-yl sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133103 CHEBI:133105 (3alpha,5alpha,17beta)-3-hydroxyandrostan-17-yl sulfate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133105 CHEBI:77344 1-stearoyl-2-linoleoyl-sn-glycero-3-phospho-1D-myo-inositol 5-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77344 CHEBI:77343 1-stearoyl-2-linoleoyl-sn-glycero-3-phospho-1D-myo-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77343 CHEBI:77342 2-oleoyl-sn-glycero-3-phosphoserine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77342 CHEBI:77348 1,2-dilinoleoyl-sn-glycero-3-phospho-1D-myo-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77348 CHEBI:77347 1-stearoyl-2-oleoyl-sn-glycero-3-phospho-1D-myo-inositol 5-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77347 CHEBI:77346 1-stearoyl-2-oleoyl-sn-glycero-3-phospho-1D-myo-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77346 CHEBI:53353 GHB receptor agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53353 CHEBI:77345 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-1D-myo-inositol 5-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77345 CHEBI:53348 benzenesulfonates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53348 CHEBI:769 16-methoxytabersonine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_769 CHEBI:28384 vitamin K biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28384 CHEBI:28383 alpha,omega-dicarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28383 CHEBI:28386 4-hydroxycinnamyl alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28386 PR:000001120 apelin receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001120 APLNR|APJ|G-protein coupled receptor APJ|angiotensin receptor-like 1|MSR|AGTRL1|G-protein coupled receptor HG11 A rhodopsin-like G-protein coupled receptor that is a translation product of the human APLNR gene or a 1:1 ortholog thereof. The preferred ligand is apelin. CHEBI:28390 (R)-1-aminopropan-2-yl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28390 CHEBI:28393 beta-D-glucosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28393 PR:000001122 bombesin receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001122 A rhodopsin-like G-protein coupled receptor that is a translation product of the human NMBR, GRPR, or BRS3 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds bombesin (a 14 amino acid peptide originally isolated from the skin of a frog) or its homologs. Mammalian homologs of bombesin include gastrin-releasing peptide and neuromedin-B. PR:000001121 beta adrenergic receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001121 An adrenoceptor protein whose active form binds adrenaline and related compounds and whose activity is mediated by G proteins that cause activation of adenylate cyclase. CHEBI:766 estriol 16-O-(beta-D-glucuronide) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_766 CHEBI:77351 novapikromycin(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77351 CHEBI:77350 neopikromycin(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77350 PR:000001123 bradykinin receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001123 A rhodopsin-like G-protein coupled receptor that is a translation product of the human BDKRB1 or BDKRB2 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds bradykinin. CHEBI:763 algestone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_763 CHEBI:77355 1-palmityl-2-arachidonoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77355 PR:000001128 chemokine receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001128 A rhodopsin-like G-protein coupled receptor that in active form binds to one or more chemokines. CHEBI:77354 novamethymycin(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77354 CHEBI:77353 neomethymycin(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77353 CHEBI:7285 N-(D-glucopyranosyl)nicotinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_7285 CHEBI:77352 methymycin(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77352 CHEBI:77358 CDP-dipalmitoyl-sn-glycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77358 CHEBI:77357 1-palmityl-2-oleoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77357 CHEBI:53339 olefinic fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53339 CHEBI:53338 3-hydroxy-3-methyl-2-oxopentanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_53338 CHEBI:28398 butan-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28398 CHEBI:28395 (+-)-trans-acenaphthene-1,2-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28395 CHEBI:28394 enol-oxaloacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28394 CHEBI:28397 cis-4-hydroxy-L-proline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28397 CHEBI:28396 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-1,2-diacyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28396 PR:000001131 cysteinyl leukotriene receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001131 A leukotriene receptor that in active form binds cysteinyl leukotriene. PR:000001130 cholecystokinin receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001130 fam:CCK_R A rhodopsin-like G-protein coupled receptor that is a translation product of the human CCKAR or CCKBR genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds cholecystokinin (CCK). PR:000001133 endothelin receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001133 A rhodopsin-like G-protein coupled receptor that is a translation product of the human EDNRA or EDNRB genes, 1:1 orthologs thereof, or pro-orthologs thereof. The active form binds endothelins. PR:000001135 interleukin-1 alpha biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001135 IL-1 alpha|hematopoietin-1|IL1F1|IL1A An interleukin-1 that is a translation product of the human IL1A gene or a 1:1 ortholog thereof. Critical mediator of the immune and inflammatory responses. CHEBI:776 16alpha-hydroxyestrone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_776 PR:000001134 growth hormone secretagogue/motilin receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001134 A rhodopsin-like G-protein coupled receptor whose active form binds either growth hormone secretagogues (principally ghrelin) or motilin. The motilin and ghrelin receptors are about 45% identical in amino acid sequence. CHEBI:77360 (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77360 PR:000001136 interleukin-1 beta biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001136 IL-1 beta|catabolin|IL1F2|IL1B An interleukin-1 that is a translation product of the human IL1B gene or a 1:1 ortholog thereof. CHEBI:77366 (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77366 CHEBI:53335 (S)-3-hydroxy-3-methyl-2-oxopentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53335 CHEBI:77369 1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77369 CHEBI:77368 (11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77368 CHEBI:28368 novobiocin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28368 PR:000001193 beta-2 adrenergic receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001193 beta(2)-adrenergic receptor|ADRB2|beta-2 adrenoreceptor|B2AR|ADRB2R|beta-2 adrenoceptor A beta adrenergic receptor that is a translation product of the human ADRB2 gene or a 1:1 ortholog thereof. PR:000001192 beta-1 adrenergic receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001192 beta-1 adrenoreceptor|ADRB1|B1AR|ADRB1R|beta-1 adrenoceptor A beta adrenergic receptor that is a translation product of the human ADRB1 gene or a 1:1 ortholog thereof. CHEBI:28364 all-cis-5,8,11,14,17-icosapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28364 PR:000001194 beta-3 adrenergic receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001194 ADRB3|beta-3 adrenoreceptor|B3bar|B3AR|ADRB3R|beta-3 adrenoceptor A beta adrenergic receptor that is a translation product of the human ADRB3 gene or a 1:1 ortholog thereof. PR:000001186 alpha-2A adrenergic receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001186 alpha-2A adrenoreceptor|alpha-2AAR|ADRA2R|alpha-2A adrenoceptor|ADRA2A|alpha-2 adrenergic receptor subtype C10|ADRAR An alpha-2 adrenergic receptor that is a translation product of the human ADRA2A gene or a 1:1 ortholog thereof. PR:000001185 alpha-1D adrenergic receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001185 alpha-1D adrenoreceptor|ADRA1D|alpha-adrenergic receptor 1a|alpha-1D adrenoceptor|ADRA1A|Gpcr8|alpha-1A adrenergic receptor An alpha-1 adrenergic receptor that is a translation product of the human ADRA1D gene or a 1:1 ortholog thereof. PR:000001188 alpha-2C adrenergic receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001188 alpha-2 adrenergic receptor subtype C4|alpha-2C adrenoreceptor|ADRA2RL2|alpha-2CAR|ADRA2C|ADRA2L2|alpha-2C adrenoceptor An alpha-2 adrenergic receptor that is a translation product of the human ADRA2C gene or a 1:1 ortholog thereof. PR:000001187 alpha-2B adrenergic receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001187 alpha-2B adrenoreceptor|ADRA2RL1|alpha-2 adrenergic receptor subtype C2|alpha-2BAR|ADRA2B|alpha-2B adrenoceptor|ADRA2L1 An alpha-2 adrenergic receptor that is a translation product of the human ADRA2B gene or a 1:1 ortholog thereof. CHEBI:77372 (13Z,16Z,19Z,22Z,25Z)-octacosapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77372 CHEBI:77371 (8Z,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77371 CHEBI:77370 1-palmitoyl-2-acyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77370 CHEBI:77377 (12Z,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77377 CHEBI:77379 (17Z,20Z,23Z,26Z,29Z)-dotriacontapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77379 CHEBI:28377 plastoquinone-9 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28377 CHEBI:28376 6-acetamido-2-oxohexanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28376 CHEBI:28379 (R)-3-methyl-2-oxovaleric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28379 CHEBI:43991 malonamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_43991 CHEBI:28375 dTDP-3-amino-3,4,6-trideoxy-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28375 PR:000001197 chemokine receptor CCR1/3/1L biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001197 A chemokine receptor that is a translation product of the human CCR1 or CCR3 genes, the mouse CCR1L1 gene, 1:1 orthologs thereof, or a semi-ortholog thereof. UBERON:0011932 pilosebaceous unit biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011932 pilosebaceous apparatus|pilo-sebaceous unit|fabrica pilosebacea|pilosebaceous gland|pilo-sebaceous apparatus An epidermal invagination that has as parts a hair follicle, a sebaceous gland, and arrector pili muscle PR:000001199 C-C chemokine receptor type 2 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001199 C-C CKR-2|MCP-1-R|CC-CKR-2|CCR2|MCP-1 receptor|CMKBR2|chemokine receptor CCR2|CCR-2|monocyte chemoattractant protein 1 receptor|JE/FIC receptor|CD192 A chemokine receptor that is a translation product of the human CCR2 gene or a 1:1 ortholog thereof. The preferred ligands include CCL2, CCL7, CCL8, CCL13. UBERON:0011931 nasal hair biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011931 hair of nose|hair of vestibular part of nose|nose hair Hair in the nose UBERON:0011930 preganglionic parasympathetic fiber biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011930 parasympathetic preganglionic fiber A cholinergic axonal fibers projecting from the CNS to a parasympathetic ganglion CHEBI:799 3,17-dioxoandrost-4-en-19-al biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_799 CHEBI:798 19-hydroxytestosterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_798 CHEBI:43997 N(6),N(6)-dimethyl-L-lysine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_43997 CHEBI:77388 tricaprin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77388 CHEBI:77387 2,3-dihexanoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77387 CHEBI:53310 copolymer macromolecule biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53310 CHEBI:77386 tricaproin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77386 CHEBI:791 17beta-estradiol 17-glucosiduronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_791 CHEBI:77389 trilaurin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77389 CHEBI:363227 6alpha,20xi-murideoxycholic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_363227 CHEBI:53309 polyanionic macromolecule biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53309 CHEBI:28349 alpha-L-fucoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28349 CHEBI:28343 3-O-alpha-mycarosylerythronolide B biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28343 PR:000001171 B1 bradykinin receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001171 B1R|BDKRB1|Bdkrb|BRADYB1|BK-1 receptor A bradykinin receptor that is a translation product of the human BDKRB1 gene or a 1:1 ortholog thereof. The preferred ligand is bradykinin. CHEBI:28340 L-2-aminobutyrate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28340 PR:000001172 B2 bradykinin receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001172 BKR2|B2R|BDKRB2|BK-2 receptor A bradykinin receptor that is a translation product of the human BDKRB2 gene or a 1:1 ortholog thereof. The preferred ligand is bradykinin. CHEBI:77391 trimyristin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77391 UBERON:0011921 connecting stalk blood islands biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011921 blood island of umbilical vesicle|insula sanguinea vesiculae umbilicalis CHEBI:77390 2,3-didodecanoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77390 UBERON:0011926 postganglionic sympathetic fiber biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011926 sympathetic postganglionic fiber|postganglionic sympathetic fiber A noradrenergic or adrenergic axonal fiber projecting from a sympathetic ganglion to an effector organ CHEBI:77395 2,3-distearoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77395 CHEBI:77394 2,3-dipalmitoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77394 UBERON:0011925 preganglionic autonomic fiber biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011925 preganglionic autonomic fibre|preganglionic nerve fiber Nerve fibers which project from the central nervous system to autonomic ganglia. In the sympathetic division most preganglionic fibers originate with neurons in the intermediolateral column of the spinal cord, exit via ventral roots from upper thoracic through lower lumbar segments, and project to the paravertebral ganglia; there they either terminate in synapses or continue through the splanchnic nerves to the prevertebral ganglia. In the parasympathetic division the fibers originate in neurons of the brain stem and sacral spinal cord. In both divisions the principal transmitter is acetylcholine but peptide cotransmitters may also be released. CHEBI:77393 tripalmitin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77393 UBERON:0011924 postganglionic autonomic fiber biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011924 postganglionic autonomic fibre|postganglionic nerve fiber Nerve fibers which project from cell bodies of autonomic ganglia to synapses on target organs. CHEBI:43986 N(6),N(6)-dimethyl-AMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_43986 CHEBI:77392 2,3-dimyristoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77392 CHEBI:77399 D-alpha-phenylglycine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77399 UBERON:0011929 postganglionic parasympathetic fiber biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011929 parasympathetic postganglionic fiber A cholinergic axonal fiber projecting from a parasympathetic ganglion to an effector organ CHEBI:77398 2-amino-2-phenylacetonitrile biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77398 UBERON:0011927 preganglionic sympathetic fiber biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011927 sympathetic preganglionic fiber A cholinergic axonal fiber projecting from the CNS to a sympathetic ganglion CHEBI:77396 long-chain primary fatty alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77396 CHEBI:28359 (-)-beta-pinene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28359 CHEBI:28358 rac-lactic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_28358 CHEBI:28354 1-deoxy-D-xylulose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28354 PR:000001182 adrenocorticotropic hormone receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001182 ACTHR|MC2R|melanocortin receptor 2|adrenocorticotropin receptor|ACTH receptor|MC2-R|ACTH-R A melanocortin receptor that is a translation product of the human MC2R gene or a 1:1 ortholog thereof. The preferred ligand is ACTH. PR:000001184 alpha-1B adrenergic receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001184 alpha-1B adrenoreceptor|ADRA1B|alpha-1B adrenoceptor An alpha-1 adrenergic receptor that is a translation product of the human ADRA1B gene or a 1:1 ortholog thereof. CHEBI:28353 4-hydroxycinnamaldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_28353 PR:000001183 alpha-1A adrenergic receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001183 alpha-1A adrenoreceptor|ADRA1A|alpha-1A adrenoceptor|alpha-1C adrenergic receptor|alpha-adrenergic receptor 1c|ADRA1C An alpha-1 adrenergic receptor that is a translation product of the human ADRA1A gene or a 1:1 ortholog thereof. UBERON:0011919 yolk sac blood island biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0011919 visceral yolk sac blood island|yolk sac blood islands masses of developing blood cells attached to endothelium in the yolk sac CHEBI:67939 erythrodiol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67939 CHEBI:133172 2-hydroxydecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133172 CHEBI:133174 2-hydroxydecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133174 CHEBI:133134 prostaglandin H3(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133134 CHEBI:133133 prostaglandin G3(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133133 CHEBI:133135 chromenochromene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133135 PR:000001105 C5a anaphylatoxin chemotactic receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001105 A complement peptide receptor whose active form binds C5a anaphylatoxin. CHEBI:133132 prostaglandin E3(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_133132 CHEBI:133131 spiro-epoxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_133131 CHEBI:77307 cardioprotective agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77307 CHEBI:77305 1-(Z)-alk-1-enyl-2-acylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77305 CHEBI:67987 ginsenoside Rg1 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67987 CHEBI:53391 poly(3-hydroxyvalerate) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_53391 CHEBI:53390 poly(hydroxyvalerate) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53390 CHEBI:53392 poly(5-hydroxyvalerate) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_53392 PR:000001113 interleukin-25 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001113 IL-17E|IL-25|IL25|interleukin-17E|IL17E An interleukin-17 that is a translation product of the human IL25 gene or a 1:1 ortholog thereof. CHEBI:67989 ginsenoside Rb1 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67989 CHEBI:67988 ginsenoside Rd biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67988 PR:000001115 alpha-1 adrenergic receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001115 An adrenoceptor protein whose active form binds adrenaline and related compounds and whose activity is mediated by G proteins that activate a phosphatidylinositol-calcium second messenger system. PR:000001116 alpha-2 adrenergic receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001116 An adrenoceptor protein whose active form binds adrenaline and related compounds and whose activity is mediated by G proteins that cause inhibition of adenylate cyclase. PR:000001119 animal opsin biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000001119 opsin receptor|type II opsin A rhodopsin-like G-protein coupled receptor that is a translation product of the human OPN1LW, OPN1MW, OPN1SW, RHO, OPN3, OPN4, or OPN5 genes, 1:1 orthologs thereof, or a semi-ortholog thereof in Metazoa. The active form binds a vitamin A-based retinaldehyde chromophore through a Schiff base linkage to a Lys residue in the seventh transmembrane alpha helix. CHEBI:77304 1-(Z)-alk-1-enyl-2-palmitoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77304 CHEBI:77303 1-(Z)-alk-1-enyl-2-palmitoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77303 CHEBI:77302 1-(Z)-alk-1-enyl-2-stearoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77302 CHEBI:77301 1-(Z)-alk-1-enyl-2-octanoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77301 CHEBI:77318 pregnane X receptor agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77318 CHEBI:67991 (20S)-ginsenoside Rg3 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_67991 CHEBI:53388 poly(hydroxybutyrate) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53388 CHEBI:77310 (E)-2-methylpentadec-2-enoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_77310 CHEBI:53387 poly(hydroxyalkanoate) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53387 CHEBI:732 5beta-dihydrocortisol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_732 CHEBI:53376 gamma-poly(glutamate) macromolecule biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53376 CHEBI:77326 androstane receptor agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_77326 CHEBI:53373 gamma-poly(glutamic acid) macromolecule biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_53373 GO:0033769 glyceollin synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033769 MetaCyc:2.5.1.36-RXN|EC:1.14.13.85 2-(or 4-)dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan,NADPH:oxygen oxidoreductase (cyclizing) activity|dimethylallyl-3,6a,9-trihydroxypterocarpan cyclase activity Catalysis of the reactions: 2-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan + NADPH + H+ + O2 = glyceollin + NADP+ + 2 H2O, and 4-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan + NADPH + H+ + O2 = glyceollin + NADP+ + 2 H2O. GO:0033768 SUMO-targeted ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033768 A nuclear ubiquitin ligase complex that specifically targets SUMOylated proteins; the complex is formed of homodimers or heterodimers of RNF4 family ubiquitin ligases and is conserved in eukaryotes. GO:0033767 4-hydroxyacetophenone monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033767 EC:1.14.13.84|RHEA:22916|UM-BBD_reactionID:r0756|MetaCyc:1.14.13.84-RXN|KEGG_REACTION:R06892 (4-hydroxyphenyl)ethan-1-one,NADPH:oxygen oxidoreductase (ester-forming) activity|HAPMO Catalysis of the reaction: 4'-hydroxyacetophenone + H(+) + NADPH + O(2) = 4-hydroxyphenyl acetate + H(2)O + NADP(+). GO:0033766 2-hydroxyquinoline 8-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033766 RHEA:22080|EC:1.14.13.61|KEGG_REACTION:R05158|MetaCyc:1.14.13.61-RXN 2-oxo-1,2-dihydroquinoline 8-monooxygenase activity|quinolin-2(1H)-one,NADH:oxygen oxidoreductase (8-oxygenating) activity Catalysis of the reaction: H(+) + NADH + O(2) + quinolin-2-ol = H(2)O + NAD(+) + quinoline-2,8-diol. GO:0018128 obsolete peptidyl-serine cyclase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018128 EC:4.2.1.- peptidyl-serine cyclase activity OBSOLETE. (Was not defined before being made obsolete). GO:0018127 NAD(P)-serine ADP-ribosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018127 Catalysis of the reaction: NAD(P)+ + L-serine = nicotinamide + N2-(ADP-D-ribosyl)-L-serine. GO:0018129 peptidyl-oxazoline dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018129 Catalysis of the reduction of a peptide-linked oxazoline to oxazole. CHEBI:138463 N-(12-oxojasmonyl)-L-alpha-amino acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138463 GO:0018124 peptide cross-linking via 5'-(N6-L-lysine)-L-topaquinone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018124 RESID:AA0233 The cross-linking of the epsilon-amino group of a peptidyl-lysine with peptidyl-topaquinone, a modified tyrosine residue. GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033765 Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor, and in which one substrate is a sterol derivative. GO:0018123 peptidyl-cysteine ADP-ribosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018123 RESID:AA0169 The transfer, from NAD, of ADP-ribose to peptidyl-cysteine to form peptidyl-S-(ADP-ribosyl)-L-cysteine. CHEBI:138462 (3R)-1,2-didehydro-3-hydroxy-2,3-dihydrotabersoninium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138462 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033764 Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative. GO:0033763 proline 3-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033763 EC:1.14.11.28|MetaCyc:1.14.11.28-RXN|RHEA:20265 P-3-H|L-proline,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity Catalysis of the reaction: L-proline + 2-oxoglutarate + O2 = cis-3-hydroxy-L-proline + succinate + CO2. CHEBI:138461 (3R)-3-hydroxy-2,3-dihydrotabersoninium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138461 GO:0018126 protein hydroxylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018126 protein amino acid hydroxylation The addition of a hydroxy group to a protein amino acid. GO:0018125 peptidyl-cysteine methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018125 RESID:AA0234 The methylation of peptidyl-cysteine to form peptidyl-S-methyl-L-cysteine. GO:0033762 response to glucagon biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033762 response to glucagon stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus. GO:0033761 mugineic-acid 3-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033761 EC:1.14.11.25|RHEA:14509|MetaCyc:RXN-7982|KEGG_REACTION:R07186 mugineic acid,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity|IDS2 Catalysis of the reactions: mugineic acid + 2-oxoglutarate + O2 = 3-epihydroxymugineic acid + succinate + CO2. GO:0018120 peptidyl-arginine ADP-ribosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018120 RESID:AA0168 The transfer, from NAD, of ADP-ribose to peptidyl-arginine to form omega-N-(ADP-ribosyl)-L-arginine. GO:0033760 2'-deoxymugineic-acid 2'-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033760 KEGG_REACTION:R07185|EC:1.14.11.24|MetaCyc:1.14.11.24-RXN|RHEA:12200 2'-deoxymugineic acid,2-oxoglutarate:oxygen oxidoreductase (2-hydroxylating) activity|IDS3 Catalysis of the reaction: 2'-deoxymugineate + 2-oxoglutarate + O(2) = CO(2) + H(+) + mugineate + succinate. GO:0018122 peptidyl-asparagine ADP-ribosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018122 RESID:AA0231 The transfer, from NAD, of ADP-ribose to peptidyl-asparagine to form peptidyl-N4-(ADP-ribosyl)-L-asparagine. GO:0018121 NAD(P)-asparagine ADP-ribosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018121 Catalysis of the reaction: NAD(P)+ + L-asparagine = nicotinamide + N2-(ADP-D-ribosyl)-L-asparagine. CHEBI:138464 N-(12-hydroxy-12-oxojasmonyl)-L-alpha-amino acid dianion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138464 GO:0018140 peptide cross-linking via L-cysteine thiazolecarboxylic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018140 RESID:AA0244 The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl cysteine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation. GO:0033759 flavone synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033759 EC:1.14.20.5|RHEA:10448|MetaCyc:RXN-8000 flavone synthase I activity|FNS I|flavanone,2-oxoglutarate:oxygen oxidoreductase (dehydrating) activity Catalysis of the reaction: a flavanone + 2-oxoglutarate + O2 = a flavone + succinate + CO2 + H2O. CHEBI:138481 N(5),N(5),N(5)-trimethyl-N(2)-[(3R)-3-(acyloxy)acyl]-L-ornithine betaine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138481 GO:0033758 clavaminate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033758 MetaCyc:1.14.11.21-RXN|RHEA:20021|EC:1.14.11.21 clavaminate synthase 2 activity|clavaminic acid synthase activity|deoxyamidinoproclavaminate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity Catalysis of the reactions: deoxyamidinoproclavaminate + 2-oxoglutarate + O2 = amidinoproclavaminate + succinate + CO2 + H2O; proclavaminate + 2-oxoglutarate + O2 = dihydroclavaminate + succinate + CO2 + 2 H2O; and dihydroclavaminate + 2-oxoglutarate + O2 = clavaminate + succinate + CO2 + 2 H2O. CHEBI:138480 N(5),N(5)-dimethyl-N(2)-[(3R)-3-(acyloxy)acyl]-L-ornithine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138480 GO:0033757 glucoside 3-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033757 RHEA:16589|Wikipedia:Glucoside_3-dehydrogenase|MetaCyc:GLUCOSIDE-3-DEHYDROGENASE-RXN|EC:1.1.99.13 hexopyranoside-cytochrome c oxidoreductase|D-aldohexopyranoside dehydrogenase|D-aldohexoside:cytochrome c oxidoreductase|D-aldohexoside:acceptor 3-oxidoreductase|D-aldohexoside:(acceptor) 3-oxidoreductase Catalysis of the reaction: sucrose + acceptor = 3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced acceptor. GO:0033756 Oplophorus-luciferin 2-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033756 RHEA:20417|MetaCyc:RXN-3361|EC:1.13.12.13 Oplophorus luciferase activity|Oplophorus-luciferin:oxygen 2-oxidoreductase (decarboxylating) activity Catalysis of the reaction: Oplophorus luciferin + O2 = oxidized Oplophorus luciferin + CO2 + hnu. GO:0033755 sulfur oxygenase/reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033755 RHEA:13957|MetaCyc:1.13.11.55-RXN|EC:1.13.11.55 sulfur:oxygen oxidoreductase (hydrogen-sulfide- and sulfite-forming) activity|sulfur oxygenase activity|sulphur oxygenase/reductase activity|SOR Catalysis of the reaction: 4 sulfur + 4 H2O + O2 = 2 hydrogen sulfide + 2 bisulfite + 2 H+. GO:0043102 amino acid salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043102 Any process which produces an amino acid from derivatives of it, without de novo synthesis. GO:0043101 purine-containing compound salvage biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0043101 purine salvage Any process that generates a purine-containing compound, any nucleobase, nucleoside, nucleotide or nucleic acid that contains a purine base, from derivatives of them without de novo synthesis. GO:0043104 positive regulation of GTP cyclohydrolase I activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043104 upregulation of GTP cyclohydrolase I activity|up regulation of GTP cyclohydrolase I activity|activation of GTP cyclohydrolase I activity|stimulation of GTP cyclohydrolase I activity|up-regulation of GTP cyclohydrolase I activity Any process that activates or increases the activity of the enzyme GTP cyclohydrolase I. GO:0043103 hypoxanthine salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043103 adenine, hypoxanthine and their nucleoside salvage|guanine, xanthine and their nucleoside salvage Any process that generates hypoxanthine, 6-hydroxy purine, from derivatives of it without de novo synthesis. GO:0043100 pyrimidine nucleobase salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043100 pyrimidine base salvage Any process that generates pyrimidine nucleobases, 1,3-diazine organic nitrogenous bases, from derivatives of them without de novo synthesis. GO:0043109 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043109 GO:0018139 peptide cross-linking via L-phenylalanine thiazolecarboxylic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018139 RESID:AA0243 The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl phenylalanine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation. GO:0043106 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043106 GO:0043105 negative regulation of GTP cyclohydrolase I activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043105 down regulation of GTP cyclohydrolase I activity|downregulation of GTP cyclohydrolase I activity|down-regulation of GTP cyclohydrolase I activity|inhibition of GTP cyclohydrolase I activity Any process that stops or reduces the activity of the enzyme GTP cyclohydrolase I. GO:0018138 peptide cross-linking via L-serine thiazolecarboxylic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018138 RESID:AA0242 The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl serine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation. GO:0043108 pilus retraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043108 The process of withdrawing a pilus back into a cell. GO:0043107 type IV pilus-dependent motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043107 social gliding motility|twitching motility|type four pilus-dependent motility|TFP-dependent motility|type 4 pilus-dependent motility|TFP-dependent movement Any process involved in the controlled movement of a bacterial cell which is dependent on the presence of type IV pili. Includes social gliding motility and twitching motility. GO:0033754 indoleamine 2,3-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033754 MetaCyc:RXN-8665|MetaCyc:RXN-8664|RHEA:14189|EC:1.13.11.52 IDO|D-tryptophan:oxygen 2,3-oxidoreductase (decyclizing) activity|tryptophan pyrrolase activity Catalysis of the reaction: tryptophan + O2 = N-formylkynurenine. The product of the reaction depends on the substrate; D-tryptophan produces N-formyl-D-kynurenine, and L-tryptophan produces N-formyl-L-kynurenine. GO:0018135 obsolete peptidyl-cysteine cyclase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018135 EC:4.2.1.- peptidyl-cysteine cyclase activity OBSOLETE. (Was not defined before being made obsolete). CHEBI:138473 N(2)-[(3R)-3-(2-saturated-acyloxy)acyl]-L-ornithine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138473 GO:0018134 peptide cross-linking via glycine oxazolecarboxylic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018134 RESID:AA0240 The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl glycine cross-link by the condensation of a serine hydroxyl with the carbonyl of the preceding residue and alpha-beta dehydrogenation. GO:0033753 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0033753 GO:0033752 acetylacetone-cleaving enzyme activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033752 RHEA:12877|EC:1.13.11.50 acetylacetone-cleaving enzyme|Dke1|acetylacetone dioxygenase activity|acetylacetone:oxygen oxidoreductase activity|diketone cleaving dioxygenase activity|diketone cleaving enzyme Catalysis of the reaction: pentane-2,4-dione + O2 = acetate + 2-oxopropanal. GO:0018137 peptide cross-linking via glycine thiazolecarboxylic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018137 RESID:AA0241 The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl glycine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation. GO:0033751 linoleate 8R-lipoxygenase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033751 RHEA:22392 linoleate diol synthase activity|7,8-linoleate diol synthase (bifunctional enzyme)|5,8-linoleate diol synthase (bifunctional enzyme) Catalysis of the reaction: linoleate + O2 = (9Z,12Z)-(7S,8S)-dihydroxyoctadeca-9,12-dienoate. GO:0018136 peptidyl-thiazoline dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018136 Catalysis of the reduction of a peptide-linked thiazoline to thiazole. GO:0018131 oxazole or thiazole biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018131 oxazole or thiazole anabolism|oxazole or thiazole synthesis|oxazole or thiazole biosynthesis|oxazole or thiazole formation The chemical reactions and pathways resulting in the formation of oxazole or thiazole, five-membered heterocyclic ring structures containing an oxygen and a sulfur, respectively, in the 1-position and a nitrogen in the 3-position. GO:0033750 ribosome localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033750 ribosome localisation|establishment of ribosome localisation|establishment of ribosome localization A process in which a ribosome is transported to, and/or maintained in, a specific location. CHEBI:138478 N(5)-methyl-N(2)-[(3R)-3-(acyloxy)acyl]-L-ornithine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138478 GO:0018130 heterocycle biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018130 heterocycle anabolism|heterocycle biosynthesis|heterocycle synthesis|heterocycle formation The chemical reactions and pathways resulting in the formation of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings). GO:0018133 peptide cross-linking via L-cysteine oxazolinecarboxylic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018133 RESID:AA0239 The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl cysteine cross-link by the condensation of a serine hydroxyl with the carbonyl of the preceding residue. GO:0018132 peptide cross-linking via L-cysteine oxazolecarboxylic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018132 RESID:AA0238 The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl cysteine cross-link by the condensation of a serine hydroxyl with the carbonyl of the preceding residue and alpha-beta dehydrogenation. GO:0033749 histone demethylase activity (H4-R3 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033749 Catalysis of the removal of a methyl group from arginine at position 3 of the histone H4 protein. GO:0033748 hydrogenase (acceptor) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033748 EC:1.12.99.6|MetaCyc:RXN0-5256|RHEA:12116|MetaCyc:RXN0-4141 uptake hydrogenase activity|hydrogen-lyase activity|H2 producing hydrogenase activity|hydrogen:(acceptor) oxidoreductase activity|hydrogenlyase activity|hydrogen:acceptor oxidoreductase activity Catalysis of the reaction: H2 + A = AH2. GO:0033747 obsolete versatile peroxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033747 polyvalent peroxidase activity|versatile peroxidase activity|reactive-black-5:hydrogen-peroxide oxidoreductase activity|VP|hybrid peroxidase activity OBSOLETE. Catalysis of the reactions: Reactive Black 5 + hydrogen peroxide = oxidized Reactive Black 5 + 2 H2O, and donor + hydrogen peroxide = oxidized donor + 2 H2O. GO:0033746 histone demethylase activity (H3-R2 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033746 Catalysis of the removal of a methyl group from arginine at position 2 of the histone H3 protein. GO:0033745 L-methionine-(R)-S-oxide reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033745 RHEA:21260|MetaCyc:1.8.4.14-RXN|EC:1.8.4.14 FRMsr|L-methionine:thioredoxin-disulfide S-oxidoreductase [L-methionine (R)-S-oxide-forming] activity|free-methionine (R)-S-oxide reductase activity|free met-R-(o) reductase activity Catalysis of the reaction: L-methionine + thioredoxin disulfide + H2O = L-methionine (R)-S-oxide + thioredoxin. GO:0008789 altronate dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008789 RHEA:15957|KEGG_REACTION:R01540|EC:4.2.1.7|MetaCyc:ALTRODEHYDRAT-RXN D-altronate hydro-lyase (2-dehydro-3-deoxy-D-galactonate-forming)|D-altronate hydro-lyase activity Catalysis of the reaction: D-altronate = 2-dehydro-3-deoxy-D-gluconate + H(2)O. GO:0008788 alpha,alpha-phosphotrehalase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008788 MetaCyc:TRE6PHYDRO-RXN|RHEA:23008|EC:3.2.1.93 trehalose-6-phosphate hydrolase activity|alpha,alpha-trehalose-6-phosphate phosphoglucohydrolase activity|phosphotrehalase activity Catalysis of the reaction: alpha,alpha-trehalose 6-phosphate + H2O = D-glucose + D-glucose 6-phosphate. GO:0033744 L-methionine:thioredoxin-disulfide S-oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033744 RHEA:19993|MetaCyc:1.8.4.13-RXN|KEGG_REACTION:R07606|EC:1.8.4.13 acetylmethionine sulfoxide reductase activity|L-methionine:oxidized-thioredoxin S-oxidoreductase activity|L-methionine-(S)-S-oxide reductase activity|methionine sulfoxide reductase activity|fSMsr|methionine-S-oxide reductase activity|free-methionine (S)-S-oxide reductase activity|methyl sulfoxide reductase I and II activity Catalysis of the reaction: L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. GO:0043113 receptor clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043113 The receptor metabolic process that results in grouping of a set of receptors at a cellular location, often to amplify the sensitivity of a signaling response. GO:0008787 allose kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008787 MetaCyc:ALLOSE-KINASE-RXN|RHEA:14805|EC:2.7.1.55 D-allokinase activity|D-allose-6-kinase activity|ATP:D-allose 6-phosphotransferase activity|allokinase activity|allokinase (phosphorylating) Catalysis of the reaction: ATP + D-allose = ADP + D-allose 6-phosphate. GO:0043112 receptor metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043112 receptor metabolism The chemical reactions and pathways involving a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. GO:0008786 allose 6-phosphate isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008786 RHEA:28430|MetaCyc:RXN0-303 Catalysis of the reaction: D-allose-6-phosphate = D-allulose-6-phosphate. GO:0043115 precorrin-2 dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043115 MetaCyc:DIMETHUROPORDEHYDROG-RXN|KEGG_REACTION:R03947|EC:1.3.1.76|RHEA:15613 dihydrosirohydrochlorin dehydrogenase activity|siroheme synthase activity|precorrin-2:NAD+ oxidoreductase activity|Met8p|CysG|SirC|precorrin-2 oxidase activity|1,3-dimethyluroporphyrinogen III dehydrogenase activity Catalysis of the reaction: NAD(+) + precorrin-2 = 2 H(+) + NADH + sirohydrochlorin. GO:0008785 alkyl hydroperoxide reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008785 Reactome:R-HSA-1222526|UM-BBD_reactionID:r0684 Catalysis of the reaction: octane hydroperoxide + NADH + H+ = H2O + NAD+ + 1-octanol. GO:0043114 regulation of vascular permeability biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043114 Any process that modulates the extent to which blood vessels can be pervaded by fluid. GO:0008784 alanine racemase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008784 RHEA:20249|KEGG_REACTION:R00401|EC:5.1.1.1|MetaCyc:ALARACECAT-RXN L-alanine racemase activity Catalysis of the reaction: L-alanine = D-alanine. GO:0008783 agmatinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008783 RHEA:13929|KEGG_REACTION:R01157|EC:3.5.3.11|Reactome:R-HSA-350604|MetaCyc:AGMATIN-RXN SpeB|agmatine ureohydrolase activity|agmatine amidinohydrolase Catalysis of the reaction: agmatine + H(2)O = putrescine + urea. GO:0008782 adenosylhomocysteine nucleosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008782 MetaCyc:ADENOSYLHOMOCYSTEINE-NUCLEOSIDASE-RXN|RHEA:17805|EC:3.2.2.9 AdoHcy/MTA nucleosidase activity|S-adenosylhomocysteine nucleosidase activity|5'-methyladenosine nucleosidase activity|S-adenosyl-L-homocysteine homocysteinylribohydrolase activity|S-adenosylhomocysteine/5'-methylthioadenosine nucleosidase activity|S-adenosylhomocysteine hydrolase activity Catalysis of the reaction: S-adenosyl-L-homocysteine + H2O = adenine + S-D-ribosyl-L-homocysteine. GO:0008781 N-acylneuraminate cytidylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008781 Reactome:R-HSA-4084982|MetaCyc:ACYLNEURAMINATE-CYTIDYLYLTRANSFERASE-RXN|RHEA:11344|EC:2.7.7.43 cytidine 5'-monophosphosialic acid synthetase activity|CMP-sialate synthetase activity|acetylneuraminate cytidylyltransferase activity|cytidine 5-monophosphate N-acetylneuraminic acid synthetase activity|CMP-N-acetylneuraminic acid synthase activity|cytidine 5'-monophospho-N-acetylneuraminic acid synthetase activity|acylneuraminate cytidyltransferase activity|cytidine monophosphosialic acid synthetase activity|CMP-N-acetylneuraminate synthetase activity|cytidine monophosphoacetylneuraminic synthetase activity|CMP-sialic synthetase activity|CMP-Neu5Ac synthetase activity|CMP-sialate pyrophosphorylase activity|CMP-sialate synthase activity|CMP-sialic acid synthetase activity|CMP-sialate diphosphorylase activity|CMP-NeuNAc synthetase activity|CMP-NeuAc synthetase activity|CTP:N-acylneuraminate cytidylyltransferase activity|CMP-N-acetylneuraminate synthase activity|CMP-N-acetylneuraminic acid synthetase activity|cytidine monophosphosialate pyrophosphorylase activity|cytidine monophosphosialate synthetase activity|CMP-NANA synthetase activity Catalysis of the reaction: CTP + N-acylneuraminate = diphosphate + CMP-N-acylneuraminate. GO:0043111 replication fork arrest biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043111 replication fork blocking|replication fork stalling|negative regulation of DNA replication at replication fork barrier Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication by impeding the progress of the DNA replication fork. Replication fork arrest is one of the 'quality control' processes ensuring that DNA-dependent DNA replication occurs correctly. DNA replication fork arrest during DNA-dependent DNA replication is not known to occur outside of cases where a replication error needs to be prevented or corrected. GO:0043110 rDNA spacer replication fork barrier binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043110 RFB binding Interacting selectively and non-covalently with replication fork barriers found in rDNA spacers, sites that inhibit replication forks in the direction opposite to rDNA transcription. GO:0008780 acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008780 RHEA:13925|MetaCyc:UDPNACETYLGLUCOSAMACYLTRANS-RXN|EC:2.3.1.129 UDP-N-acetylglucosamine acyltransferase activity|uridine diphosphoacetylglucosamine acyltransferase activity|acyl-ACP-UDP-N-acetylglucosamine O-acyltransferase activity|acyl-acyl-carrier-protein-UDP-N-acetylglucosamine O-acyltransferase|acyl-[acyl-carrier protein]-UDP-N-acetylglucosamine O-acyltransferase activity|(R)-3-hydroxytetradecanoyl-acyl-carrier-protein:UDP-N-acetylglucosamine 3-O-(3-hydroxytetradecanoyl)transferase activity Catalysis of the reaction: (R)-3-hydroxytetradecanoyl-[acyl-carrier protein] + UDP-N-acetylglucosamine = [acyl-carrier protein] + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine. GO:0008790 arabinose isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008790 MetaCyc:DARABISOM-RXN|EC:5.3.1.3|RHEA:13849 D-arabinose(L-fucose) isomerase activity|D-arabinose isomerase activity|D-arabinose aldose-ketose-isomerase activity|D-arabinose ketol-isomerase activity Catalysis of the reaction: D-arabinose = D-ribulose. GO:0018109 peptidyl-arginine phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018109 RESID:AA0222 The phosphorylation of peptidyl-arginine to form omega-N-phospho-L-arginine. GO:0018106 peptidyl-histidine phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018106 RESID:AA0036|RESID:AA0035 The phosphorylation of peptidyl-histidine to form peptidyl-1'-phospho-L-histidine (otherwise known as tau-phosphohistidine, tele-phosphohistidine) or peptidyl-3'-phospho-L-histidine (otherwise known as pi-phosphohistidine, pros-phosphohistidine). GO:0043117 positive regulation of vascular permeability biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043117 up regulation of vascular permeability|activation of vascular permeability|stimulation of vascular permeability|up-regulation of vascular permeability|upregulation of vascular permeability Any process that increases the extent to which blood vessels can be pervaded by fluid. GO:0018105 peptidyl-serine phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018105 RESID:AA0037 The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine. GO:0043116 negative regulation of vascular permeability biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043116 down regulation of vascular permeability|downregulation of vascular permeability|down-regulation of vascular permeability|inhibition of vascular permeability Any process that reduces the extent to which blood vessels can be pervaded by fluid. GO:0018108 peptidyl-tyrosine phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018108 RESID:AA0039 The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine. GO:0043119 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043119 GO:0018107 peptidyl-threonine phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018107 RESID:AA0038 The phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine. GO:0043118 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043118 GO:0033743 peptide-methionine (R)-S-oxide reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033743 RHEA:24164|MetaCyc:1.8.4.12-RXN|Reactome:R-HSA-5676917|KEGG_REACTION:R07607|EC:1.8.4.12 methionine S-oxide reductase (R-form oxidizing) activity|methionine sulfoxide reductase activity|peptide-methionine:thioredoxin-disulfide S-oxidoreductase [methionine (R)-S-oxide-forming] activity|methionine S-oxide reductase activity|SelX|pMSR|SelR|MsrB|pMRsr|methionine sulfoxide reductase B activity|PilB|selenoprotein R|protein-methionine-R-oxide reductase activity Catalysis of the reaction: peptide-L-methionine + H(2)O + thioredoxin disulfide = peptide-L-methionine (R)-S-oxide + thioredoxin. Can act on oxidized methionine in peptide linkage with specificity for the R enantiomer. Thioredoxin disulfide is the oxidized form of thioredoxin. CHEBI:138441 (3R,4R)-3-acyl-4-(hydroxymethyl)oxolan-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138441 GO:0018102 peptidyl-arginine hydroxylation to peptidyl-4-hydroxy-L-arginine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018102 RESID:AA0215 The hydroxylation of peptidyl-arginine to form peptidyl-4-hydroxy-L-arginine. GO:0018101 protein citrullination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018101 RESID:AA0214 peptidyl-citrulline biosynthetic process from peptidyl-arginine|peptidyl-citrulline synthesis from peptidyl-arginine|peptidyl-citrulline anabolism from peptidyl-arginine|deimination|peptidyl-citrulline formation from peptidyl-arginine The hydrolysis of peptidyl-arginine to form peptidyl-citrulline. GO:0033742 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0033742 CHEBI:138440 (3R,4R)-3-[(1S)-1-hydroxyalkyl]-4-(hydroxymethyl)oxolan-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138440 GO:0018104 peptidoglycan-protein cross-linking biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018104 The process of covalently linking peptidoglycan (murein) to proteins. GO:0033741 adenylyl-sulfate reductase (glutathione) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033741 RHEA:14141|MetaCyc:1.8.4.9-RXN|KEGG_REACTION:R05717|EC:1.8.4.9 5'-adenylylsulfate reductase activity|AMP,sulfite:glutathione-disulfide oxidoreductase (adenosine-5'-phosphosulfate-forming) activity|plant-type 5'-adenylylsulfate reductase activity|AMP,sulfite:oxidized-glutathione oxidoreductase (adenosine-5'-phosphosulfate-forming) activity Catalysis of the reaction: AMP + glutathione disulfide + H(+) + sulfite = 5'-adenylyl sulfate + 2 glutathione. GO:0033740 hydroxylamine oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033740 EC:1.7.2.8|MetaCyc:1.7.99.8-RXN|RHEA:23232 hydroxylamine:acceptor oxidoreductase activity Catalysis of the reactions: hydroxylamine + NH3 = hydrazine + H2O, and hydrazine + acceptor = N2 + reduced acceptor. GO:0018103 protein C-linked glycosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018103 RESID:AA0217 protein amino acid C-linked glycosylation A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via a C atom. CHEBI:138445 O(3)-(poly[beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)]-beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-serine polyanionic residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138445 CHEBI:138444 O(3)-(beta-D-GlcA-(1->3)-poly[beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)]-beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-serine polyanionic residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138444 CHEBI:138443 O(3)-(beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-serine(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138443 CHEBI:138442 O(3)-(beta-D-GlcA-(1->3)-beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-serine(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138442 GO:0033739 preQ1 synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033739 RHEA:13409|MetaCyc:RXN0-4022|EC:1.7.1.13|KEGG_REACTION:R07605 preQ0 oxidoreductase activity|queuine:NADP+ oxidoreductase activity|preQ0 reductase activity|YkvM|7-cyano-7-deazaguanine reductase activity|QueF|7-aminomethyl-7-carbaguanine:NADP+ oxidoreductase activity|queuine synthase activity Catalysis of the reaction: 7-aminomethyl-7-deazaguanine + 2 NADP(+) = 7-cyano-7-deazaguanine + 3 H(+) + 2 NADPH. GO:0033738 methylenetetrahydrofolate reductase (ferredoxin) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033738 RHEA:14229|MetaCyc:RXN-5061|EC:1.5.7.1 5-methyltetrahydrofolate:ferredoxin oxidoreductase activity|5,10-methylenetetrahydrofolate reductase activity Catalysis of the reaction: 5-methyltetrahydrofolate + oxidized ferredoxin = 5,10-methylenetetrahydrofolate + reduced ferredoxin. GO:0033737 1-pyrroline dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033737 EC:1.2.1.19|MetaCyc:1.5.1.35-RXN YdcW|gamma-aminobutyraldehyde dehydrogenase activity|1-pyrroline:NAD+ oxidoreductase activity|ABALDH Catalysis of the reaction: 1-pyrroline + NAD+ + 2 H2O = 4-aminobutanoate + NADH + 2 H+. GO:0033736 L-lysine 6-oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033736 RHEA:22548|EC:1.4.3.20|KEGG_REACTION:R07598|MetaCyc:1.4.3.20-RXN L-lysine-epsilon-oxidase activity|L-lysine:oxygen 6-oxidoreductase (deaminating) activity|marinocine|Lod|LodA Catalysis of the reaction: L-lysine + H(2)O + O(2) = allysine + H(2)O(2) + NH(4)(+). GO:0033735 aspartate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033735 EC:1.4.1.21|KEGG_REACTION:R07165|KEGG_REACTION:R07164|MetaCyc:1.4.1.21-RXN L-aspartate:NAD(P)+ oxidoreductase (deaminating) activity|NADP+-dependent aspartate dehydrogenase activity|NAD-dependent aspartate dehydrogenase activity|NADH2-dependent aspartate dehydrogenase activity Catalysis of the reaction: L-aspartate + H2O + NAD(P)+ = oxaloacetate + NH3 + NAD(P)H + H+. GO:0033734 (R)-benzylsuccinyl-CoA dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033734 RHEA:20876|UM-BBD_reactionID:r0330|EC:1.3.8.3 BbsG|(R)-benzylsuccinyl-CoA:acceptor oxidoreductase activity|(R)-benzylsuccinyl-CoA:(acceptor) oxidoreductase activity Catalysis of the reaction: (R)-2-benzylsuccinyl-CoA + 2 electron-transferring flavoprotein = (E)-2-benzylidenesuccinyl-CoA + 2 reduced electron-transferring flavoprotein. CHEBI:2290 7alpha-hydroxy-5beta-cholestan-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_2290 GO:0008799 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008799 GO:0033733 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0033733 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043124 negative regulation of I-kappaB kinase/NF-kappaB cascade|down regulation of I-kappaB kinase/NF-kappaB cascade|downregulation of I-kappaB kinase/NF-kappaB cascade|down-regulation of I-kappaB kinase/NF-kappaB cascade|inhibition of I-kappaB kinase/NF-kappaB cascade Any process that stops, prevents, or reduces the frequency, rate or extent of -kappaB kinase/NF-kappaB signaling. GO:0008798 beta-aspartyl-peptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008798 Reactome:R-HSA-5692495|EC:3.4.19.5|Reactome:R-HSA-5696365|MetaCyc:3.4.19.5-RXN beta-aspartyl peptidase activity|beta-aspartyl dipeptidase activity Catalysis of the cleavage of a beta-linked aspartic residue from the N-terminus of a polypeptide. GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043123 up-regulation of I-kappaB kinase/NF-kappaB cascade|upregulation of I-kappaB kinase/NF-kappaB cascade|stimulation of I-kappaB kinase/NF-kappaB cascade|up regulation of I-kappaB kinase/NF-kappaB cascade|activation of I-kappaB kinase/NF-kappaB cascade|positive regulation of I-kappaB kinase/NF-kappaB cascade Any process that activates or increases the frequency, rate or extent of I-kappaB kinase/NF-kappaB signaling. GO:0008797 aspartate ammonia-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008797 RHEA:16601|EC:4.3.1.1|MetaCyc:ASPARTASE-RXN L-aspartase activity|aspartase activity|L-aspartate ammonia-lyase activity|L-aspartate ammonia-lyase (fumarate-forming)|fumaric aminase activity Catalysis of the reaction: L-aspartate = fumarate + NH3. GO:0043126 regulation of 1-phosphatidylinositol 4-kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043126 regulation of PI4K activity Any process that modulates the activity of the enzyme 1-phosphatidylinositol 4-kinase. GO:0008796 bis(5'-nucleosyl)-tetraphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008796 EC:3.6.1.- Catalysis of the hydrolysis of P(1),P(4)-bis(5'-nucleosyl)tetraphosphate into two nucleotides. GO:0008795 NAD+ synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008795 EC:6.3.1.5|MetaCyc:NAD-SYNTH-NH3-RXN|RHEA:21188 deamido-NAD+:ammonia ligase (AMP-forming)|NAD synthase activity|diphosphopyridine nucleotide synthetase activity|NAD+ synthetase activity|NAD synthase (AMP-forming)|nicotinamide adenine dinucleotide synthetase activity|NAD(+) synthetase activity|NAD synthetase activity Catalysis of the reaction: ATP + deamido-NAD+ + NH3 = AMP + diphosphate + NAD+. GO:0043125 ErbB-3 class receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043125 HER3 receptor binding|Neu/ErbB-2 receptor activity Interacting selectively and non-covalently with the protein-tyrosine kinase receptor ErbB-3/HER3. GO:0008794 arsenate reductase (glutaredoxin) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008794 EC:1.20.4.1|MetaCyc:RXN-982|UM-BBD_reactionID:r0635|RHEA:22016 glutharedoxin:arsenate oxidoreductase activity Catalysis of the reaction: arsenate + reduced glutaredoxin = arsenite + oxidized glutaredoxin. Glutaredoxin functions as the electron donor for arsenate reduction. The electron flow therefore is ( NADPH -> glutathione reductase (EC:1.6.4.2) -> ) glutathione -> glutaredoxin -> arsenate reductase, i.e. glutathione is reduced by glutathione reductase and glutaredoxin is reduced by glutathione. GO:0043120 tumor necrosis factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043120 Interacting selectively and non-covalently with tumor necrosis factor, a proinflammatory cytokine produced by monocytes and macrophages. GO:0008793 aromatic-amino-acid:2-oxoglutarate aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008793 RHEA:17533|MetaCyc:2.6.1.57-RXN|EC:2.6.1.57|UM-BBD_reactionID:r0297 aromatic amino acid aminotransferase activity|aromatic amino acid transferase activity|ArAT|aromatic aminotransferase activity|aromatic-amino-acid transaminase activity Catalysis of the reaction: an aromatic amino acid + 2-oxoglutarate = an aromatic oxo acid + L-glutamate. GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043122 regulation of I-kappaB kinase/NF-kappaB cascade Any process that modulates I-kappaB kinase/NF-kappaB signaling. GO:0008792 arginine decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008792 RHEA:17641|Reactome:R-HSA-350598|EC:4.1.1.19|MetaCyc:ARGDECARBOX-RXN|KEGG_REACTION:R00566 L-arginine carboxy-lyase activity|L-arginine carboxy-lyase (agmatine-forming)|SpeA Catalysis of the reaction: L-arginine + H(+) = agmatine + CO(2). GO:0043121 neurotrophin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043121 neurotrophin TRK receptor activity|neurotrophic factor binding|neurotrophin-4/5 binding|NT 4/5 binding|neurotrophin-3 binding|NT-4/5 binding|NT5 binding|NT-5 binding|NT4 binding|NT-4 binding|NT3 binding|neurotrophin 4/5 binding|NT-3 binding|neurotrophin TRKC receptor activity|neurotrophin TRKB receptor activity|neurotrophin 3 binding|neurotrophin TRKA receptor activity Interacting selectively and non-covalently with a neurotrophin, any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth. GO:0008791 arginine N-succinyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008791 RHEA:15185|MetaCyc:ARGININE-N-SUCCINYLTRANSFERASE-RXN|EC:2.3.1.109 AOST activity|AstA|succinyl-CoA:L-arginine 2-N-succinyltransferase activity|arginine succinyltransferase activity|arginine and ornithine N2-succinyltransferase activity|AST activity|succinyl-CoA:L-arginine N2-succinyltransferase activity|arginine and ornithine N(2)-succinyltransferase activity Catalysis of the reaction: succinyl-CoA + L-arginine = CoA + N2-succinyl-L-arginine. CHEBI:2288 7alpha,12alpha-dihydroxy-5beta-cholestan-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_2288 GO:0043128 positive regulation of 1-phosphatidylinositol 4-kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043128 up regulation of 1-phosphatidylinositol 4-kinase activity|positive regulation of PI4K activity|upregulation of 1-phosphatidylinositol 4-kinase activity|stimulation of 1-phosphatidylinositol 4-kinase activity|up-regulation of 1-phosphatidylinositol 4-kinase activity|activation of 1-phosphatidylinositol 4-kinase activity Any process that activates or increases the activity of 1-phosphatidylinositol 4-kinase. GO:0018117 protein adenylylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018117 protein adenylation|protein AMPylation|protein amino acid adenylylation The addition of an adenylyl group (adenosine 5'-monophosphate; AMP) to a protein amino acid. GO:0043127 negative regulation of 1-phosphatidylinositol 4-kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043127 downregulation of 1-phosphatidylinositol 4-kinase activity|down regulation of 1-phosphatidylinositol 4-kinase activity|inhibition of 1-phosphatidylinositol 4-kinase activity|negative regulation of PI4K activity|down-regulation of 1-phosphatidylinositol 4-kinase activity Any process that stops or reduces the activity of the enzyme 1-phosphatidylinositol 4-kinase. GO:0018116 peptidyl-lysine adenylylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018116 RESID:AA0227 peptidyl-lysine adenylation The adenylylation of peptidyl-lysine to form peptidyl-N6-(phospho-5'-adenosine)-L-lysine. GO:0018119 peptidyl-cysteine S-nitrosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018119 RESID:AA0230 protein S-nitrosylation|S-nitrosylation The covalent addition of a nitric oxide (NO) group to the sulphur (S) atom of a cysteine residue in a protein, to form peptidyl-S-nitrosyl-L-cysteine. GO:0018118 peptidyl-L-cysteine glutathione disulfide biosynthetic process from peptidyl-cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018118 RESID:AA0229 peptidyl-L-cysteine glutathione disulfide synthesis from peptidyl-cysteine|peptidyl-L-cysteine glutathione disulphide biosynthetic process from peptidyl-cysteine|peptidyl-L-cysteine glutathione disulphide biosynthesis from peptidyl-cysteine|peptidyl-L-cysteine glutathione disulfide anabolism from peptidyl-cysteine|peptidyl-L-cysteine glutathione disulfide formation from peptidyl-cysteine The modification of peptidyl-cysteine by covalent addition of glutathione to form peptidyl-L-cysteine glutathione disulfide. GO:0043129 surfactant homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043129 Any process involved in the maintenance of a steady-state level of the surface-active lipoprotein mixture which coats the alveoli. GO:0033732 pyrroloquinoline-quinone synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033732 EC:1.3.3.11|RHEA:10692|KEGG_REACTION:R07353|MetaCyc:1.3.3.11-RXN PqqC|6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,5,6,7,8-octahydroquinoline-2,4-dicarboxylate:oxygen oxidoreductase (cyclizing) activity Catalysis of the reaction: 6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O(2) = 2 H(2)O + 2 H(2)O(2) + H(+) + pyrroloquinoline quinone. GO:0018113 lysine racemase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018113 MetaCyc:LYSINE-RACEMASE-RXN|RHEA:22864|EC:5.1.1.5 Catalysis of the reaction: L-lysine = D-lysine. GO:0033731 arogenate dehydrogenase [NAD(P)+] activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033731 EC:1.3.1.79|MetaCyc:1.3.1.79-RXN L-arogenate:NAD(P)+ oxidoreductase (decarboxylating) activity|arogenic dehydrogenase activity|pretyrosine dehydrogenase activity Catalysis of the reaction: L-arogenate + NAD(P)+ = L-tyrosine + NAD(P)H + CO2. GO:0018112 proline racemase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018112 MetaCyc:PROLINE-RACEMASE-RXN|KEGG_REACTION:R01255|RHEA:10680|EC:5.1.1.4 Catalysis of the reaction: L-proline = D-proline. GO:0018115 peptidyl-S-diphytanylglycerol diether-L-cysteine biosynthetic process from peptidyl-cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018115 RESID:AA0223 peptidyl-S-diphytanylglycerol diether-L-cysteine anabolism from peptidyl-cysteine|peptidyl-S-diphytanylglycerol diether-L-cysteine formation from peptidyl-cysteine|peptidyl-S-diphytanylglycerol diether-L-cysteine synthesis from peptidyl-cysteine The modification of cysteine to form peptidyl-S-diphytanylglycerol diether-L-cysteine. GO:0033730 arogenate dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033730 EC:1.3.1.78|RHEA:15417|MetaCyc:1.3.1.78-RXN TyrAa|TyrAAT2|arogenic dehydrogenase activity|TyrAAT1|pretyrosine dehydrogenase activity|L-arogenate:NADP+ oxidoreductase (decarboxylating) activity Catalysis of the reaction: L-arogenate + NADP+ = L-tyrosine + NADPH + CO2. GO:0018114 threonine racemase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018114 MetaCyc:THREONINE-RACEMASE-RXN|RHEA:13913|KEGG_REACTION:R01467|EC:5.1.1.6 Catalysis of the reaction: L-threonine = D-threonine. GO:0018111 methionine racemase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018111 KEGG_REACTION:R00655|MetaCyc:METHIONINE-RACEMASE-RXN|RHEA:12492|EC:5.1.1.2 Catalysis of the reaction: L-methionine = D-methionine. GO:0018110 histone arginine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018110 EC:2.7.3.- histone-arginine kinase activity Catalysis of the reaction: histone L-arginine + ATP = histone N(omega)-phospho-L-arginine + ADP + 2 H(+). GO:0033729 anthocyanidin reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033729 MetaCyc:1.3.1.77-RXN|EC:1.3.1.77 AtANR|ANR|MtANR|flavan-3-ol:NAD(P)+ oxidoreductase activity Catalysis of the reaction: a flavan-3-ol + 2 NAD(P)+ = an anthocyanidin + 2 NAD(P)H + H+. GO:0033728 divinyl chlorophyllide a 8-vinyl-reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033728 MetaCyc:RXN-5286|EC:1.3.1.75|RHEA:14449 chlorophyllide-a:NADP+ oxidoreductase activity|[4-vinyl]chlorophyllide a reductase activity|4VCR Catalysis of the reaction: chlorophyllide a + NADP+ = divinyl chlorophyllide a + NADPH + H+. GO:0033727 aldehyde dehydrogenase (FAD-independent) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033727 MetaCyc:1.2.99.3-RXN|MetaCyc:CARBOXYLATE-REDUCTASE-RXN|EC:1.2.99.7|MetaCyc:1.2.99.7-RXN aldehyde oxidoreductase activity|Mop|aldehyde:acceptor oxidoreductase (FAD-independent) activity|AORDd Catalysis of the reaction: an aldehyde + H2O + acceptor = a carboxylate + reduced acceptor. GO:0033726 aldehyde ferredoxin oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033726 EC:1.2.7.5|RHEA:16421|MetaCyc:1.2.7.5-RXN AOR|aldehyde:ferredoxin oxidoreductase activity|tungsten-containing aldehyde ferredoxin oxidoreductase activity Catalysis of the reaction: an aldehyde + H2O + 2 oxidized ferredoxin = an acid + 2 H+ + 2 reduced ferredoxin. GO:0008769 obsolete X-His dipeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008769 EC:3.4.13.3|MetaCyc:3.4.13.3-RXN aminoacyl-histidine dipeptidase activity|homocarnosinase activity|dipeptidase M|aminoacylhistidine dipeptidase activity|X-His dipeptidase activity|Xaa-His dipeptidase activity|carnosinase activity OBSOLETE. Catalysis of the hydrolysis of Xaa-His dipeptides. GO:0033725 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0033725 GO:0033724 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0033724 GO:0008768 UDP-sugar diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008768 EC:3.6.1.45|Reactome:R-HSA-6810464|MetaCyc:UDPSUGARHYDRO-RXN UDP-sugar pyrophosphatase activity|nucleosidediphosphate-sugar pyrophosphatase activity|nucleosidediphosphate-sugar diphosphatase activity|UDP-sugar sugarphosphohydrolase activity|UDP-sugar hydrolase activity Catalysis of the reaction: UDP-sugar + H2O = UMP + sugar 1-phosphate. GO:0008767 UDP-galactopyranose mutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008767 EC:5.4.99.9|MetaCyc:GALPMUT-RXN|RHEA:24132 UDP-D-galactopyranose furanomutase activity|UDPgalactopyranose mutase activity Catalysis of the reaction: UDP-D-galactopyranose = UDP-D-galacto-1,4-furanose. GO:0033723 fluoroacetaldehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033723 RHEA:16677|EC:1.2.1.69 fluoroacetaldehyde:NAD+ oxidoreductase activity Catalysis of the reaction: fluoroacetaldehyde + NAD+ + H2O = fluoroacetate + NADH + 2 H+. UBERON:0005705 primary palate mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005705 Mesenchyme that is part of a developing primary palate. UBERON:0005704 secondary palatal shelf mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005704 palatal shelf mesenchyme Mesenchyme that is part of a developing secondary palatal shelf. GO:0033722 malonate-semialdehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033722 EC:1.2.1.15|MetaCyc:MALONATE-SEMIALDEHYDE-DEHYDROGENASE-RXN malonic semialdehyde dehydrogenase activity|3-oxopropanoate:NAD(P)+ oxidoreductase activity Catalysis of the reaction: 3-oxopropanoate + NAD(P)+ + H2O = malonate + NAD(P)H + H+. GO:0008766 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008766 MetaCyc:UDP-NACMURALGLDAPAALIG-RXN|RHEA:28374|EC:6.3.2.- Catalysis of the reaction: ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminoheptanedioate + D-alanyl-D-alanine = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanyl-D-alanine. GO:0008765 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008765 MetaCyc:UDP-NACMURALGLDAPLIG-RXN|KEGG_REACTION:R02788|EC:6.3.2.13|RHEA:23676 UDP-N-acetylmuramyl-tripeptide synthetase activity|UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelate synthetase activity|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:(L)-meso-2,6-diaminoheptanedioate gamma-ligase (ADP-forming)|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:meso-2,6-diamino-heptanedioate ligase (ADP-forming) activity|MurE synthetase activity Catalysis of the reaction: meso-2,6-diaminopimelate + ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate = ADP + 2 H(+) + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioate. GO:0043135 5-phosphoribosyl 1-pyrophosphate pyrophosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043135 MetaCyc:RXN-10969 PRPP pyrophosphatase activity Catalysis of the reaction: 5-phospho-alpha-D-ribose 1-diphosphate + H2O = ribose 1,5 bisphosphate + phosphate + H+. GO:0008764 UDP-N-acetylmuramoylalanine-D-glutamate ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008764 MetaCyc:UDP-NACMURALA-GLU-LIG-RXN|EC:6.3.2.9|RHEA:16429|KEGG_REACTION:R02783 MurD synthetase activity|UDP-N-acetylmuramoyl-L-alanine:glutamate ligase (ADP-forming)|D-glutamate ligase activity|uridine diphospho-N-acetylmuramoylalanyl-D-glutamate synthetase activity|UDP-Mur-NAC-L-Ala:D-Glu ligase activity|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase activity|D-glutamate-adding enzyme activity Catalysis of the reaction: D-glutamate + ATP + UDP-N-acetylmuramoyl-L-alanine = ADP + 2 H(+) + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate. GO:0043134 regulation of hindgut contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043134 Any process that modulates the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine. GO:0008763 UDP-N-acetylmuramate-L-alanine ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008763 MetaCyc:UDP-NACMUR-ALA-LIG-RXN|EC:6.3.2.8|RHEA:23372|KEGG_REACTION:R03193 UDP-N-acetylmuramoyl-L-alanine synthetase activity|L-Ala ligase activity|UDP-acetylmuramyl-L-alanine synthetase activity|L-alanine-adding enzyme activity|alanine-adding enzyme activity|UDP-N-acetylmuramoylalanine synthetase activity|uridine diphospho-N-acetylmuramoylalanine synthetase activity|uridine diphosphate N-acetylmuramate:L-alanine ligase activity|uridine 5'-diphosphate-N-acetylmuramyl-L-alanine synthetase activity|UDP-N-acetylmuramyl:L-alanine ligase activity|uridine-diphosphate-N-acetylmuramate:L-alanine ligase activity|MurC synthetase activity|UDPMurNAc-L-alanine synthetase activity|UDP-MurNAc:L-alanine ligase activity|UDP-N-acetylmuramate:L-alanine ligase (ADP-forming) Catalysis of the reaction: L-alanine + ATP + UDP-N-acetylmuramate = ADP + 2 H(+) + phosphate + UDP-N-acetylmuramoyl-L-alanine. GO:0043137 DNA replication, removal of RNA primer biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043137 Okazaki initiator RNA removal Removal of the Okazaki RNA primer from the lagging strand of replicating DNA, by a combination of the actions of DNA polymerase, DNA helicase and an endonuclease. GO:0008762 UDP-N-acetylmuramate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008762 MetaCyc:UDPNACETYLMURAMATEDEHYDROG-RXN|EC:1.3.1.98|RHEA:12248 UDP-N-acetylenolpyruvoylglucosamine reductase activity|uridine diphospho-N-acetylglucosamine-enolpyruvate reductase activity|UDP-GlcNAc-enoylpyruvate reductase activity|UDP-N-acetylmuramate:NADP+ oxidoreductase activity|MurB reductase|UDP-N-acetylglucosamine-enoylpyruvate reductase activity|uridine diphosphoacetylpyruvoylglucosamine reductase activity|uridine-5'-diphospho-N-acetyl-2-amino-2-deoxy-3-O-lactylglucose:NADP-oxidoreductase activity Catalysis of the reaction: UDP-N-acetylmuramate + NADP+ = UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine + NADPH + H+. GO:0043136 glycerol-3-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043136 Reactome:R-HSA-8955794|MetaCyc:GLYCEROL-1-PHOSPHATASE-RXN Catalysis of the reaction: glycerol 3-phosphate + H2O = glycerol + phosphate. GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008761 Reactome:R-HSA-4088338|EC:5.1.3.14|MetaCyc:UDPGLCNACEPIM-RXN|RHEA:17213|Reactome:R-HSA-4085021 UDP-GlcNAc-2-epimerase activity|UDP-N-acetylglucosamine 2'-epimerase activity|UDP-N-acetyl-D-glucosamine 2-epimerase activity|uridine diphospho-N-acetylglucosamine 2'-epimerase activity|uridine diphosphate-N-acetylglucosamine-2'-epimerase activity|uridine diphosphoacetylglucosamine 2'-epimerase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-mannosamine. GO:0043131 erythrocyte enucleation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043131 The process in which nucleated precursor cells lose their nucleus during erythrocyte maturation. GO:0043130 ubiquitin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043130 Reactome:R-HSA-983152|Reactome:R-HSA-1169404|Reactome:R-HSA-205008 Interacting selectively and non-covalently with ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation. GO:0008760 UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008760 KEGG_REACTION:R00660|EC:2.5.1.7|MetaCyc:UDPNACETYLGLUCOSAMENOLPYRTRANS-RXN|RHEA:18681 MurA transferase activity|UDP-N-acetylglucosamine 1-carboxyvinyl-transferase activity|phosphoenolpyruvate:uridine-5'-diphospho-N-acetyl-2-amino-2-deoxyglucose 3-enolpyruvyltransferase activity|phosphopyruvate-uridine diphosphoacetylglucosamine pyruvatetransferase activity|phosphoenolpyruvate:uridine diphosphate N-acetylglucosamine enolpyruvyltransferase activity|phosphoenolpyruvate:UDP-N-acetyl-D-glucosamine 1-carboxyvinyltransferase activity|enoylpyruvate transferase activity|pyruvate-uridine diphospho-N-acetylglucosamine transferase activity|pyruvate-uridine diphospho-N-acetyl-glucosamine transferase activity|phosphoenolpyruvate-UDP-acetylglucosamine-3-enolpyruvyltransferase activity|pyruvate-UDP-acetylglucosamine transferase activity|phosphoenolpyruvate:UDP-2-acetamido-2-deoxy-D-glucose 2-enoyl-1-carboxyethyltransferase activity|pyruvic-uridine diphospho-N-acetylglucosaminyltransferase activity|UDP-N-acetylglucosamine enoylpyruvyltransferase activity Catalysis of the reaction: phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine. GO:0043133 hindgut contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043133 A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the hindgut. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The hindgut is the posterior part of the alimentary canal, including the rectum, and the large intestine. GO:0043132 NAD transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043132 reduced nicotinamide adenine dinucleotide transport|reduced NAD transport|oxidized nicotinamide adenine dinucleotide transport|oxidized NAD transport|NAD (reduced) transport|NAD (oxidized) transport|NADH transport|nicotinamide adenine dinucleotide transport The directed movement of nicotinamide adenine dinucleotide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore; transport may be of either the oxidized form, NAD, or the reduced form, NADH. GO:0043139 5'-3' DNA helicase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043139 Reactome:R-HSA-6782131 ATP-dependent 5'-3' DNA helicase activity|DNA helicase IV activity|ATP-dependent 5' to 3' DNA helicase activity|5' to 3' DNA helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate; drives the unwinding of the DNA helix in the direction 5' to 3'. GO:0043138 3'-5' DNA helicase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043138 Reactome:R-HSA-9684118|Reactome:R-HSA-75949|Reactome:R-HSA-9613498|Reactome:R-HSA-167097|Reactome:R-HSA-9613490|Reactome:R-HSA-9613494|Reactome:R-HSA-174438|Reactome:R-HSA-9613497 ATP-dependent 3' to 5' DNA helicase activity|ATP-dependent 3'-5' DNA helicase activity|3' to 5' DNA helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate; drives the unwinding of the DNA helix in the direction 3' to 5'. CHEBI:138429 isopimarane diterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138429 GO:0033721 aldehyde dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033721 EC:1.2.1.4|RHEA:11888|MetaCyc:ALDEHYDE-DEHYDROGENASE-NADP+-RXN NADP-acetaldehyde dehydrogenase activity|NADP-dependent aldehyde dehydrogenase activity|aldehyde:NADP+ oxidoreductase activity Catalysis of the reaction: an aldehyde + NADP+ + H2O = an acid + NADPH + H+. GO:0033720 (S)-mandelate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033720 EC:1.1.99.31|RHEA:15749|UM-BBD_reactionID:r1048|MetaCyc:MANDELATE-DEHYDROGENASE-RXN|MetaCyc:MANDELATE-OXY-RXN MDH|L(+)-mandelate dehydrogenase activity|(S)-2-hydroxy-2-phenylacetate:acceptor 2-oxidoreductase activity Catalysis of the reaction: (S)-2-hydroxy-2-phenylacetate + acceptor = 2-oxo-2-phenylacetate + reduced acceptor. UBERON:0005712 midgut duodenum mesentery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005712 A mesentery of duodenum that is part of a midgut. UBERON:0005711 foregut duodenum mesentery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005711 A mesentery of duodenum that is part of a foregut. GO:0033718 pyranose dehydrogenase (acceptor) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033718 MetaCyc:RXN-7966|MetaCyc:RXN-7965|MetaCyc:RXN-7963|MetaCyc:RXN-7962|MetaCyc:RXN-7961|EC:1.1.99.29 pyranose dehydrogenase activity|quinone-dependent pyranose dehydrogenase activity|pyranose-quinone oxidoreductase activity|pyranose:acceptor oxidoreductase activity|PDH Catalysis of the reactions: pyranose + acceptor = 2-dehydropyranose (or 3-dehydropyranose or 2,3-didehydropyranose) + reduced acceptor, and a pyranoside + acceptor = a 3-dehydropyranoside (or 3,4-didehydropyranoside) + reduced acceptor. GO:0033717 gluconate 2-dehydrogenase (acceptor) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033717 EC:1.1.99.3|MetaCyc:GLUCONATE-2-DEHYDROGENASE-RXN|RHEA:12769 gluconic acid dehydrogenase activity|D-gluconate dehydrogenase activity|D-gluconate dehydrogenase, 2-keto-D-gluconate-yielding activity|gluconate oxidase activity|2-ketogluconate reductase activity|D-gluconate:(acceptor) 2-oxidoreductase activity|gluconic dehydrogenase activity|D-gluconate:acceptor 2-oxidoreductase activity Catalysis of the reaction: D-gluconate + acceptor = 2-dehydro-D-gluconate + reduced acceptor. GO:0043140 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043140 GO:0033716 nucleoside oxidase (hydrogen peroxide-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033716 EC:1.1.3.39|RHEA:15489|MetaCyc:1.1.3.39-RXN nucleoside:oxygen 5'-oxidoreductase (hydrogen peroxide-forming) activity Catalysis of the reactions: adenosine + 2 O2 = 9-riburonosyladenine + 2 hydrogen peroxide. GO:0033715 nucleoside oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033715 EC:1.1.3.28|RHEA:28651|MetaCyc:NUCLEOSIDE-OXIDASE-RXN nucleoside:oxygen 5'-oxidoreductase activity Catalysis of the reactions: inosine + O2 = 9-riburonosylhypoxanthine + 2 H2O; (1a) 2 inosine + O2 = 2 5'-dehydroinosine + 2 H2O, and (1b) 2 5'-dehydroinosine + O2 = 2 9-riburonosylhypoxanthine + 2 H2O. GO:0033714 secondary-alcohol oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033714 EC:1.1.3.18|KEGG_REACTION:R02277|RHEA:23180|MetaCyc:SECONDARY-ALCOHOL-OXIDASE-RXN secondary-alcohol:oxygen oxidoreductase activity|secondary alcohol oxidase activity|polyvinyl alcohol oxidase activity Catalysis of the reaction: O(2) + secondary alcohol = H(2)O(2) + ketone. GO:0008779 acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008779 EC:2.3.1.40|MetaCyc:ACYLGPEACYLTRANS-RXN|RHEA:10304 acyl-ACP-phospholipid O-acyltransferase activity|acyl-acyl-carrier-protein-phospholipid O-acyltransferase activity|acyl-acyl-carrier-protein:O-(2-acyl-sn-glycero-3-phospho)-ethanolamine O-acyltransferase activity|acyl-[acyl-carrier protein]-phospholipid O-acyltransferase activity Catalysis of the reaction: acyl-[acyl-carrier protein] + O-(2-acyl-sn-glycero-3-phospho)ethanolamine = [acyl-carrier protein] + O-(1-beta-acyl-2-acyl-sn-glycero-3-phospho)ethanolamine. GO:0033713 choline:oxygen 1-oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033713 EC:1.1.3.17|RHEA:13505|MetaCyc:CHOLINE-OXIDASE-RXN choline oxidase activity Catalysis of the reaction: choline + O2 = betaine aldehyde + hydrogen peroxide. GO:0033712 1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033712 EC:1.1.1.292|RHEA:24208|KEGG_REACTION:R08194|MetaCyc:1.1.1.292-RXN 1,5-anhydro-D-mannitol:NADP+ oxidoreductase activity|AFR Catalysis of the reaction: 1,5-anhydro-D-mannitol + NADP(+) = 1,5-anhydro-D-fructose + H(+) + NADPH. GO:0008778 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008778 GO:0008777 acetylornithine deacetylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008777 RHEA:15941|MetaCyc:ACETYLORNDEACET-RXN|EC:3.5.1.16 acetylornithinase activity|N-acetylornithinase activity|N2-acetyl-L-ornithine amidohydrolase activity|2-N-acetyl-L-ornithine amidohydrolase activity Catalysis of the reaction: N2-acetyl-L-ornithine + H2O = acetate + L-ornithine. GO:0033711 4-phosphoerythronate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033711 EC:1.1.1.290|MetaCyc:ERYTHRON4PDEHYDROG-RXN|RHEA:18829|KEGG_REACTION:R04210 erythronate-4-phosphate dehydrogenase activity|4-O-phosphoerythronate dehydrogenase activity|PdxB|PdxB 4PE dehydrogenase activity|4PE dehydrogenase activity|4-phospho-D-erythronate:NAD+ 2-oxidoreductase activity Catalysis of the reaction: 4-phospho-D-erythronate + NAD(+) = (R)-3-hydroxy-2-oxo-4-phosphonooxybutanoate + H(+) + NADH. GO:0008776 acetate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008776 RHEA:11352|EC:2.7.2.1|MetaCyc:ACETATEKIN-RXN ATP:acetate phosphotransferase activity|AK activity|acetate kinase (phosphorylating) activity|AckA|acetic kinase activity|acetokinase activity Catalysis of the reaction: ATP + acetate = ADP + acetyl phosphate. GO:0043146 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043146 GO:0008775 acetate CoA-transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008775 RHEA:13381|MetaCyc:ACECOATRANS-RXN|Reactome:R-HSA-2066788|UM-BBD_enzymeID:e0012|EC:2.8.3.8 butyryl CoA:acetate CoA transferase activity|succinyl-CoA:acetate CoA transferase activity|acetate coenzyme A-transferase activity|butyryl coenzyme A transferase activity|acetyl-CoA:acetoacetate CoA transferase activity|acyl-CoA:acetate CoA-transferase activity Catalysis of the reaction: acyl-CoA + acetate = a fatty acid anion + acetyl-CoA. GO:0043145 sno(s)RNA 3'-end cleavage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043145 sRNA 3'-end cleavage|snoRNA 3'-end cleavage|sno(s)RNA 3' end cleavage The endonucleolytic cleavage of snoRNA 3' ends, which is required for mature snoRNAs to be functional. GO:0043148 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043148 GO:0008774 acetaldehyde dehydrogenase (acetylating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008774 MetaCyc:ACETALD-DEHYDROG-RXN|RHEA:23288|EC:1.2.1.10 acetaldehyde:NAD+ oxidoreductase (CoA-acetylating)|aldehyde dehydrogenase (acylating) activity|acylating acetaldehyde dehydrogenase activity|DmpF|ADA Catalysis of the reaction: acetaldehyde + CoA + NAD+ = acetyl-CoA + NADH + H+. PR:000020497 lactotransferrin proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000020497 LTF/ClvPrd A lactotransferrin that has been processed by proteolytic cleavage. GO:0043147 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043147 GO:0008773 [protein-PII] uridylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008773 EC:2.7.7.59|MetaCyc:URITRANS-RXN|RHEA:13673 uridyl removing enzyme|UTP:protein-PII uridylyltransferase activity|PII uridylyl-transferase activity|protein-PII uridylyltransferase activity|UTP:[protein-PII] uridylyltransferase activity|uridylyl removing enzyme activity Catalysis of the reaction: UTP + (protein-PII) = diphosphate + uridylyl-(protein-PII). GO:0008772 [isocitrate dehydrogenase (NADP+)] kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008772 RHEA:43540|MetaCyc:PHOSICITDEHASE-RXN|EC:2.7.11.5 IDH kinase/phosphatase activity|isocitrate dehydrogenase (NADP) kinase activity|isocitrate dehydrogenase (NADP+) kinase activity|IDH-K/P|ICDH kinase/phosphatase activity|isocitrate dehydrogenase kinase activity|isocitrate dehydrogenase kinase/phosphatase activity|ATP:isocitrate dehydrogenase (NADP+) phosphotransferase activity|isocitrate dehydrogenase kinase (phosphorylating) activity|IDHK/P|IDH kinase activity Catalysis of the reaction: ATP + (isocitrate dehydrogenase (NADP)) = ADP + (isocitrate dehydrogenase (NADP)) phosphate. GO:0043142 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043142 GO:0008771 [citrate (pro-3S)-lyase] ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008771 MetaCyc:CITC-RXN|KEGG_REACTION:R04449|RHEA:23788|EC:6.2.1.22 acetate:citrate-(pro-3S)-lyase(thiol-form) ligase (AMP-forming)|acetate: SH-acyl-carrier-protein enzyme ligase (AMP)|citrate lyase synthetase activity|citrate lyase ligase activity|citrate (pro-3S)-lyase ligase activity|acetate:HS-citrate lyase ligase activity Catalysis of the reaction: ATP + acetate + (citrate (pro-3S)-lyase) (thiol form) = AMP + diphosphate + (citrate (pro-3S)-lyase) (acetyl form). GO:0043141 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043141 GO:0008770 [acyl-carrier-protein] phosphodiesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008770 MetaCyc:3.1.4.14-RXN|RHEA:20537|EC:3.1.4.14 holo-acyl-carrier-protein 4'-pantetheine-phosphohydrolase activity|ACP hydrolyase activity|ACP phosphodiesterase activity|[acyl-carrier-protein] 4'-pantetheine-phosphohydrolase activity|AcpH|acyl-carrier-protein phosphodiesterase activity|[acyl-carrier protein] phosphodiesterase activity|acyl-carrier-protein 4'-pantetheine-phosphohydrolase activity Catalysis of the reaction: [acyl-carrier protein] + H2O = 4'-phosphopantetheine + apoprotein. GO:0043144 sno(s)RNA processing biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0043144 Any process involved in the conversion of a primary snoRNA family RNA transcript into a mature snoRNA (eukaryota) or sRNA (archaea). GO:0033719 2-oxo-acid reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033719 MetaCyc:1.1.99.30-RXN|EC:1.1.99.30|RHEA:23664 (2R)-hydroxy-carboxylate:acceptor oxidoreductase activity|HVOR|(2R)-hydroxycarboxylate-viologen-oxidoreductase activity|2-oxoacid reductase activity Catalysis of the reaction: a (2R)-hydroxy-carboxylate + acceptor = a 2-oxo-carboxylate + reduced acceptor. GO:0043143 regulation of translation by machinery localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043143 establishment and maintenance of translational protein localization|translational machinery localization|translational protein localization|establishment and maintenance of translational machinery localization|regulation of translation by machinery localisation Any process in which proteins and protein complexes involved in translation are transported to, or maintained in, a specific location. CHEBI:138437 (S)-3-hydroxytetradecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138437 CHEBI:138436 hexadecanoyl phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138436 GO:0043149 stress fiber assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043149 actin cable assembly|stress fibre biosynthesis|actin cable formation|stress fibre formation The aggregation, arrangement and bonding together of a set of components to form a stress fiber. A stress fiber is a contractile actin filament bundle that consists of short actin filaments with alternating polarity. CHEBI:138439 [alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)]n-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-ditrans,octacis-undecaprenol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138439 GO:0033710 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0033710 CHEBI:138430 (9R,13R)-1a,1b-dinor-10,11-dihydro-12-oxo-15-phytoenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138430 UBERON:0005702 optic eminence mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005702 Mesenchyme that is part of a optic eminence. CHEBI:138434 6-{(1S,5S)-4-oxo-5-[(2Z)-pent-2-en-1-yl]cyclopent-2-en-1-yl}hexanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138434 CHEBI:138433 (9S,13S)-1a,1b-dinor-12-oxo-10,15-phytodienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138433 CHEBI:138432 6-{(1S,5S)-4-oxo-5-[(2Z)-pent-2-en-1-yl]cyclopent-2-en-1-yl}hexanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138432 CHEBI:138431 (9S,13S)-1a,1b-dinor-10,11-dihydro-12-oxo-15-phytoenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138431 CHEBI:44395 N-acetyl-beta-D-galactosamine 6-sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_44395 GO:0033707 3''-deamino-3''-oxonicotianamine reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033707 MetaCyc:1.1.1.285-RXN|EC:1.1.1.285 2'-deoxymugineic acid:NAD(P)+ 3''-oxidoreductase activity Catalysis of the reaction: 2'-deoxymugineic acid + NAD(P)+ = 3''-deamino-3''-oxonicotianamine + NAD(P)H + H+. GO:0033706 obsolete quinate/shikimate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033706 quinate/shikimate dehydrogenase activity|L-quinate:NAD(P)+ 3-oxidoreductase activity|YdiB OBSOLETE. Catalysis of the reactions: L-quinate + NAD(P)+ = 3-dehydroquinate + NAD(P)H + H+, and shikimate + NAD(P)+ = 3-dehydroshikimate + NAD(P)H + H+. GO:0033705 GDP-4-dehydro-6-deoxy-D-mannose reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033705 MetaCyc:GDP-4-DEHYDRO-D-RHAMNOSE-REDUCTASE-RXN|EC:1.1.1.281 GDP-6-deoxy-D-lyxo-4-hexulose reductase activity|GDP-6-deoxy-D-mannose:NAD(P)+ 4-oxidoreductase (D-rhamnose-forming) activity|Rmd|GDP-4-keto-6-deoxy-D-mannose reductase activity Catalysis of the reaction: GDP-6-deoxy-D-mannose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-mannose + NAD(P)H + H+. GO:0008749 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008749 GO:0043151 DNA synthesis involved in double-strand break repair via single-strand annealing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043151 DNA synthesis during double-strand break repair via single-strand annealing The synthesis of DNA that contributes to the process of double-strand break repair via single-strand annealing. GO:0008748 N-ethylmaleimide reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008748 MetaCyc:RXN0-5101|RHEA:35523 Catalysis of the reaction: N-ethylmaleimide + NADPH + 2 H+ = N-ethylsuccinimide + NADP+. GO:0033704 3beta-hydroxy-5alpha-steroid dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033704 KEGG_REACTION:R07138|RHEA:18137|MetaCyc:1.1.1.278-RXN|EC:1.1.1.278 3beta-hydroxy-5alpha-steroid:NADP+ 3-oxidoreductase activity Catalysis of the reaction: 3beta-hydroxy-5alpha-pregnane-20-one + NADP(+) = 5alpha-pregnane-3,20-dione + H(+) + NADPH. GO:0043150 DNA synthesis involved in double-strand break repair via homologous recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043150 DNA synthesis during double-strand break repair via homologous recombination The synthesis of DNA that contributes to the process of double-strand break repair via homologous recombination. GO:0008747 N-acetylneuraminate lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008747 MetaCyc:ACNEULY-RXN|KEGG_REACTION:R01811|Reactome:R-HSA-4085217|RHEA:23296|EC:4.1.3.3 N-acetylneuraminate aldolase activity|sialate lyase activity|N-acetylneuraminate pyruvate-lyase activity|acetylneuraminate pyruvate-lyase activity|NALase activity|sialic acid aldolase activity|N-acetylneuraminic aldolase activity|neuraminic aldolase activity|N-acetylneuraminate pyruvate-lyase (N-acetyl-D-mannosamine-forming)|neuraminic acid aldolase activity|N-acetylneuraminic acid lyase activity|N-acetylneuraminic acid aldolase activity|sialic aldolase activity|NPL|N-acetylneuraminic lyase activity|NANA lyase activity|acetylneuraminate lyase activity|neuraminate aldolase activity Catalysis of the reaction: N-acetylneuraminate = N-acetyl-D-mannosamine + pyruvate. GO:0033703 3beta-hydroxy-5beta-steroid dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033703 KEGG_REACTION:R06166|MetaCyc:1.1.1.277-RXN|EC:1.1.1.277|RHEA:22944 3beta-hydroxysteroid 5beta-progesterone oxidoreductase activity|3beta-hydroxysteroid 5beta-oxidoreductase activity|3beta-hydroxy-5beta-steroid:NADP+ 3-oxidoreductase activity Catalysis of the reaction: 3beta-hydroxy-5beta-pregnane-20-one + NADP(+) = 5beta-pregnan-3,20-dione + H(+) + NADPH. GO:0008746 NAD(P)+ transhydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008746 EC:1.6.1.1|Reactome:R-HSA-450971|KEGG_REACTION:R00112|RHEA:11692 H+-thase|NADH transhydrogenase|energy-linked transhydrogenase|NADPH-NAD oxidoreductase|nicotinamide adenine dinucleotide (phosphate) transhydrogenase|NADH-NADP-transhydrogenase|NADPH:NAD+ transhydrogenase|NADPH-NAD transhydrogenase|pyridine nucleotide transferase|NAD transhydrogenase Catalysis of the reaction: NADPH + H+ + NAD+ = NADP+ + NADH + H+. GO:0033702 (+)-trans-carveol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033702 KEGG_REACTION:R06117|EC:1.1.1.275|RHEA:14825|MetaCyc:RXN-9397 (+)-trans-carveol:NAD+ oxidoreductase activity Catalysis of the reaction: (1R,5S)-carveol + NAD(+) = (S)-carvone + H(+) + NADH. GO:0033701 dTDP-galactose 6-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033701 MetaCyc:DTDP-GALACTOSE-6-DEHYDROGENASE-RXN|RHEA:12396|EC:1.1.1.186 dTDPgalactose 6-dehydrogenase activity|thymidine-diphosphate-galactose dehydrogenase activity|dTDP-D-galactose:NADP+ 6-oxidoreductase activity Catalysis of the reaction: dTDP-D-galactose + 2 NADP+ + H2O = dTDP-D-galacturonate + 2 NADPH + 2 H+. GO:0008745 N-acetylmuramoyl-L-alanine amidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008745 Reactome:R-HSA-6799977|EC:3.5.1.28|MetaCyc:3.5.1.28-RXN acetylmuramyl-L-alanine amidase activity|N-acetylmuramyl-L-alanine amidase activity|acetylmuramyl-alanine amidase activity|N-acetylmuramylalanine amidase activity|N-acetylmuramoyl-L-alanine amidase type II|acetylmuramoyl-alanine amidase activity|N-acylmuramyl-L-alanine amidase activity|N-acetylmuramoyl-L-alanine amidase type I|N-acetylmuramic acid L-alanine amidase activity Catalysis of the hydrolysis of the link between N-acetylmuramoyl residues and L-amino acid residues in certain bacterial cell-wall glycopeptides. GO:0008744 L-xylulokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008744 MetaCyc:LYXK-RXN|RHEA:18869|EC:2.7.1.53 L-xylulokinase (phosphorylating)|L-xylulose kinase activity|ATP:L-xylulose 5-phosphotransferase activity Catalysis of the reaction: ATP + L-xylulose = ADP + L-xylulose 5-phosphate. GO:0033700 phospholipid efflux biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033700 phospholipid export The directed movement of a phospholipid out of a cell or organelle. GO:0008743 L-threonine 3-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008743 RHEA:13161|EC:1.1.1.103|MetaCyc:THREODEHYD-RXN|KEGG_REACTION:R01465|Reactome:R-HSA-6798667 L-threonine:NAD+ oxidoreductase activity|threonine 3-dehydrogenase activity|L-threonine dehydrogenase activity|threonine dehydrogenase activity Catalysis of the reaction: L-threonine + NAD(+) = L-2-amino-3-oxobutanoate + CO(2) + NADH. GO:0043157 response to cation stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043157 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cation stress, an increase or decrease in the concentration of positively charged ions in the environment. GO:0008742 L-ribulose-phosphate 4-epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008742 RHEA:22368|MetaCyc:RIBULPEPIM-RXN|KEGG_REACTION:R05850|EC:5.1.3.4 phosphoribulose isomerase activity|ribulose phosphate 4-epimerase activity|AraD|L-ribulose-5-phosphate 4-epimerase|L-ru5P activity|L-ribulose 5-phosphate 4-epimerase activity|L-Ru5P Catalysis of the reaction: L-ribulose 5-phosphate = D-xylulose 5-phosphate. GO:0043156 chromatin remodeling in response to cation stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043156 Structural changes to eukaryotic chromatin occurring as a result of cation stress, an increase or decrease in the concentration of positively charged ions in the environment. GO:0008741 ribulokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008741 EC:2.7.1.16|MetaCyc:RIBULOKIN-RXN|RHEA:22072 L-ribulokinase activity|ribulokinase (phosphorylating)|ATP:L(or D)-ribulose 5-phosphotransferase activity Catalysis of the reaction: ATP + L(or D)-ribulose = ADP + L(or D)-ribulose 5-phosphate. GO:0043159 acrosomal matrix biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043159 A structural framework, or 'dense core' at the interior of an acrosome. May regulate the distribution of hydrolases within the acrosome and their release during the acrosome reaction. GO:0008740 L-rhamnose isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008740 MetaCyc:RHAMNISOM-RXN|KEGG_REACTION:R02437|EC:5.3.1.14|RHEA:23160 rhamnose isomerase activity|L-rhamnose aldose-ketose-isomerase activity|L-rhamnose ketol-isomerase activity Catalysis of the reaction: L-rhamnose = L-rhamnulose. GO:0043158 heterocyst differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043158 heterocyst formation|heterocyst biosynthesis|heterocyst cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a heterocyst, a differentiated cell in certain cyanobacteria whose purpose is to fix nitrogen. GO:0043153 entrainment of circadian clock by photoperiod biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043153 photoentrainment of circadian clock The synchronization of a circadian rhythm to photoperiod, the intermittent cycle of light (day) and dark (night). GO:0043152 induction of bacterial agglutination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043152 Any process in which infecting bacteria are clumped together by a host organism. GO:0043155 negative regulation of photosynthesis, light reaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043155 down regulation of photosynthesis, light reaction|inhibition of photosynthesis, light reaction|down-regulation of photosynthesis, light reaction|downregulation of photosynthesis, light reaction Any process that stops, prevents, or reduces the frequency, rate or extent of the light-dependent reaction of photosynthesis. GO:0033709 D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033709 KEGG_REACTION:R07144|MetaCyc:RXN-7972|RHEA:11868 D-arabinitol dehydrogenase 1 activity|D-arabinitol:NADP+ dehydrogenase activity|ARD1p|NADP+-dependent D-arabinitol dehydrogenase activity Catalysis of the reaction: D-arabinitol + NADP+ = D-ribulose + NADPH + H+. GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043154 down-regulation of caspase activity|inhibition of caspase activation|downregulation of caspase activity|negative regulation of caspase activity|down regulation of caspase activity|inhibition of caspase activity|negative regulation of caspase activation Any process that stops, prevents, or reduces the frequency, rate or extent of a cysteine-type endopeptidase activity involved in the apoptotic process. GO:0033708 isocitrate-homoisocitrate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033708 EC:1.1.1.286|MetaCyc:RXN-7969 PH1722|homoisocitrate-isocitrate dehydrogenase activity|isocitrate(homoisocitrate):NAD+ oxidoreductase (decarboxylating) activity Catalysis of the reactions: isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH, and (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate + NAD+ = 2-oxoadipate + CO2 + NADH + H+. CHEBI:138405 O-(S-(7Z)-tetradecenoylpantetheine-4'-phosphoryl)-L-serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138405 CHEBI:138404 (E)-hex-4-enoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138404 CHEBI:138403 O-[S-(2E,9Z)-hexadecadienoylpantetheine-4'-phosphoryl]-L-serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138403 CHEBI:138402 4,4'-disulfanyldibutanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138402 CHEBI:138408 isoprostane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138408 CHEBI:138407 O-[S-(3R)-hydroxy-(9Z)-hexadecenoylpantetheine-4'-phosphoryl]-L-serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138407 CHEBI:138406 O-{S-[(9Z)-3-oxohexadecenoylpantetheine]-4'-phosphoryl}-L-serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138406 CHEBI:138401 3alpha,7beta-dihydroxy-12-oxo-5beta-cholanic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138401 CHEBI:138400 4-sulfanylbutanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138400 GO:0043160 acrosomal lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043160 The volume enclosed within the acrosome membrane. GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043162 ubiquitin-dependent protein catabolic process via the MVB pathway|ubiquitin-dependent protein breakdown via the multivesicular body pathway|ubiquitin-dependent protein catabolism via the MVB pathway|ubiquitin-dependent protein degradation via the multivesicular body pathway The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the multivesicular body (MVB) sorting pathway; ubiquitin-tagged proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation. GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043161 proteasomal ubiquitin-dependent protein degradation|proteasomal pathway|proteasomal ubiquitin-dependent protein breakdown|proteasome pathway|proteasomal ubiquitin-dependent protein catabolic process|proteasomal processing|proteasomal ubiquitin-dependent protein catabolism The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome. GO:0008759 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008759 EC:3.5.1.108 Catalysis of the removal of an acetyl group from the 2-N position of glucosamine in the lipid A precursor UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine. GO:0008758 UDP-2,3-diacylglucosamine hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008758 RHEA:25213|MetaCyc:LIPIDXSYNTHESIS-RXN Catalysis of the reaction: H2O + UDP-2,3-bis(3-hydroxymyristoyl)glucosamine = 2,3-bis(3-hydroxymyristoyl)-beta-D-glucosaminyl 1-phosphate + UMP. GO:0008757 S-adenosylmethionine-dependent methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008757 S-adenosyl methionine-dependent methyltransferase activity|SAM-dependent methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate. GO:0008756 o-succinylbenzoate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008756 EC:6.2.1.26|RHEA:17009|KEGG_REACTION:R04030|MetaCyc:O-SUCCINYLBENZOATE-COA-LIG-RXN OSB-CoA synthetase activity|o-succinylbenzoyl-CoA synthetase activity|o-succinylbenzoyl-coenzyme A synthetase activity|2-succinylbenzoate:CoA ligase (AMP-forming)|o-succinylbenzoate:CoA ligase (AMP-forming) Catalysis of the reaction: 2-succinylbenzoate + ATP + CoA = 2-succinylbenzoyl-CoA + AMP + diphosphate. GO:0008755 O antigen polymerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008755 O-antigen polymerase activity Catalysis of the polymerization of o-antigen chains. O-antigens are tetra- and pentasaccharide repeat units of the cell walls of Gram-negative bacteria and are a component of lipopolysaccharide. GO:0043168 anion binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043168 Interacting selectively and non-covalently with anions, charged atoms or groups of atoms with a net negative charge. GO:0008754 O antigen ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008754 MetaCyc:RXN0-5294 Catalysis of the reaction: Lipid A-core + colanic acid = MLPS. GO:0043167 ion binding biolink:MolecularActivity go-plus goslim_pir|goslim_metagenomics|goslim_generic|goslim_chembl|goslim_yeast http://purl.obolibrary.org/obo/GO_0043167 atom binding Interacting selectively and non-covalently with ions, charged atoms or groups of atoms. GO:0008753 NADPH dehydrogenase (quinone) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008753 KEGG_REACTION:R07359|EC:1.6.5.10|MetaCyc:NADPH-DEHYDROGENASE-QUINONE-RXN|RHEA:46164 NADPH:(quinone-acceptor) oxidoreductase|reduced nicotinamide adenine dinucleotide phosphate (quinone) dehydrogenase|NADPH oxidase Catalysis of the reaction: NADPH + H+ + a quinone = NADP+ + a quinol. GO:0008752 FMN reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008752 EC:1.5.1.39 riboflavine mononucleotide reductase activity|riboflavin mononucleotide (reduced nicotinamide adenine dinucleotide (phosphate)) reductase activity|NAD(P)H2 dehydrogenase (FMN)|SsuE|NAD(P)H(2):FMN oxidoreductase activity|FMNH2:NAD(P)+ oxidoreductase activity|NAD(P)H(2) dehydrogenase (FMN) activity|NAD(P)H dehydrogenase (FMN) activity|NAD(P)H2:FMN oxidoreductase activity|flavine mononucleotide reductase activity|flavin mononucleotide reductase activity|NAD(P)H:FMN oxidoreductase activity|NAD(P)H-dependent FMN reductase activity|NAD(P)H-FMN reductase activity|NAD(P)H:flavin oxidoreductase activity|riboflavin mononucleotide reductase activity Catalysis of the reaction: FMNH2 + NAD(P)+ = FMN + NAD(P)H + H+. GO:0043169 cation binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043169 Interacting selectively and non-covalently with cations, charged atoms or groups of atoms with a net positive charge. GO:0008751 obsolete NAD(P)H dehydrogenase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008751 NAD(P)H dehydrogenase OBSOLETE. (Was not defined before being made obsolete). GO:0043164 Gram-negative-bacterium-type cell wall biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043164 1-2nm peptidoglycan-based cell wall biogenesis|cell wall biosynthetic process|cell wall anabolism|cell wall assembly|cell wall synthesis|cell wall formation A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall of the type found in Gram-negative bacteria. The cell wall is the rigid or semi-rigid envelope lying outside the cell membrane. GO:0008750 NAD(P)+ transhydrogenase (AB-specific) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008750 MetaCyc:1.6.1.2-RXN|EC:1.6.1.2 NAD(P) transhydrogenase (AB-specific) activity|transhydrogenase activity|NADPH:NAD+ oxidoreductase (AB-specific)|pyridine nucleotide transhydrogenase activity Catalysis of the reaction: NADPH + H+ + NAD+ = NADP+ + NADH + H+. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD+ and B-specific (i.e. the pro-S hydrogen is transferred) with respect to NADP+. GO:0043163 cell envelope organization biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0043163 cell envelope organization and biogenesis|cell envelope organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cell envelope, everything external to, but not including, the cytoplasmic membrane of bacteria, encompassing the periplasmic space, cell wall, and outer membrane if present. GO:0043166 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043166 GO:0043165 Gram-negative-bacterium-type cell outer membrane assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043165 cell outer membrane biogenesis The assembly of an outer membrane of the type formed in Gram-negative bacteria. This membrane is enriched in polysaccharide and protein, and the outer leaflet of the membrane contains specific lipopolysaccharide structures. CHEBI:83979 D-aspartic acid derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83979 CHEBI:83978 L-aspartic acid derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83978 CHEBI:83976 2-methyl fatty acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83976 CHEBI:83972 3-methyl fatty acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83972 GO:0102001 isoleucine N-monooxygenase (oxime forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102001 RHEA:28602|MetaCyc:1.14.13.117-RXN|EC:1.14.14.39 Catalysis of the reaction: L-isoleucine + 2 O2 + 2 NADPH(4-) + 2 H+ <=> (E)-2-methylbutanal oxime + 2 NADP(3-) + carbon dioxide + 3 H2O. GO:0102003 Delta8-sphingolipid desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102003 MetaCyc:1.14.19.4-RXN|EC:1.14.19.4 Catalysis of the reaction: phytosphingosine(1+) + O2 + a reduced electron acceptor <=> 4-hydroxy-trans-8-sphingenine + 2 H2O + an oxidized electron acceptor. CHEBI:83989 O-[S-(9Z)-hexadecenoylpantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83989 GO:0102002 valine N-monooxygenase (oxime forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102002 RHEA:28606|MetaCyc:1.14.13.118-RXN|EC:1.14.14.38 Catalysis of the reaction: L-valine + 2 O2 + 2 NADPH(4-) + 2 H+ <=> (E)-2-methylpropanal oxime + 2 NADP(3-) + carbon dioxide + 3 H2O. GO:0102005 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0102005 GO:0102004 2-octaprenyl-6-hydroxyphenol methylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102004 MetaCyc:2-OCTAPRENYL-6-OHPHENOL-METHY-RXN|RHEA:27770 Catalysis of the reaction: 3-(all-trans-octaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine <=> H+ + 2-methoxy-6-(all-trans-octaprenyl)phenol + S-adenosyl-L-homocysteine. GO:0102007 acyl-L-homoserine-lactone lactonohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102007 RHEA:22576|EC:3.1.1.81|Reactome:R-HSA-8932633|MetaCyc:3.1.1.81-RXN Catalysis of the reaction: H2O + an N-acyl-L-homoserine lactone <=> H+ + an N-acyl-L-homoserine. CHEBI:83985 N(2)-acylglutamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83985 GO:0102006 4-methyl-2-oxopentanoate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102006 RHEA:25177|MetaCyc:2KETO-4METHYL-PENTANOATE-DEHYDROG-RXN Catalysis of the reaction: 4-methyl-2-oxopentanoate + coenzyme A(4-) + NAD(1-) <=> isovaleryl-CoA(4-) + carbon dioxide + NADH(2-). CHEBI:83983 D-glutamic acid derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83983 GO:0102009 proline dipeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102009 MetaCyc:3.4.13.9-RXN|EC:3.4.13.9 Catalysis of the reaction: H2O + a dipeptide with proline at the C-terminal <=> L-proline + a standard alpha amino acid. CHEBI:83982 L-glutamic acid derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83982 GO:0102008 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0102008 CHEBI:83981 3-hydroxyaspartic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83981 CHEBI:83980 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1D-myo-inositol 3,4,5-triphosphate) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83980 GO:0018193 peptidyl-amino acid modification biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0018193 The alteration of an amino acid residue in a peptide. GO:0018192 obsolete enzyme active site formation via cysteine modification to L-cysteine persulfide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018192 enzyme active site formation via L-cysteine persulphide OBSOLETE. The formation of an enzyme active site via modification of peptidyl-cysteine to peptidyl-L-cysteine persulfide. GO:0018195 peptidyl-arginine modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018195 The modification of peptidyl-arginine. GO:0018194 peptidyl-alanine modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018194 The modification of peptidyl-alanine. GO:0018191 peptidyl-serine octanoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018191 RESID:AA0290 The octanoylation of peptidyl-serine to form peptidyl-O3-octanoyl-L-serine, typical of the protein ghrelin. GO:0018190 protein octanoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018190 protein amino acid octanoylation The modification of a protein amino acid by formation of an ester or amide with octanoic acid. GO:0102014 beta-D-galactose-importing ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102014 MetaCyc:ABC-18-RXN|RHEA:30011 Catalysis of the reaction: ATP(4-) + beta-D-galactoside + H2O <=> ADP(3-) + hydrogenphosphate + beta-D-galactoside + H+. GO:0102013 ATPase-coupled L-glutamate tranmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102013 MetaCyc:ABC-13-RXN L-glutamate-importing ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + L-glutamate(out) -> ADP + phosphate + L-glutamate(in). GO:0102016 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0102016 GO:0102017 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0102017 CHEBI:83992 beta-D-glucosylsphingosine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83992 CHEBI:83991 imidothioate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83991 GO:0018189 pyrroloquinoline quinone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018189 RESID:AA0283 pyrroloquinoline quinone synthesis|pyrroloquinoline quinone formation|pyrroloquinoline quinone biosynthesis|PQQ biosynthesis|PQQ biosynthetic process|coenzyme pyrroloquinoline-quinone biosynthetic process|coenzyme pyrroloquinoline-quinone biosynthesis|pyrroloquinoline-quinone biosynthetic process|pyrroloquinoline-quinone biosynthesis|pyrroloquinoline quinone anabolism The chemical reactions and pathways resulting in the formation of the cofactor pyrroloquinoline quinone (PQQ); it is synthesized from a small peptide containing tyrosine and glutamic acid; these amino acids in the peptide are multiply cross-linked and the rest of the peptide is removed. GO:0018186 peroxidase-heme linkage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018186 RESID:AA0280|RESID:AA0279 peroxidase-haem linkage The covalent linkage of heme to peroxidase. GO:0018185 poly-N-methyl-propylamination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018185 RESID:AA0278 The modification of peptidyl-lysine by the addition of an N6-propylamino and of propylmethylamino units, forming N6-(propylamino-poly(propylmethylamino)-propyldimethylamine)-L-lysine, typical of the silicate binding protein silaffin. GO:0018188 peptidyl-proline di-hydroxylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018188 RESID:AA0282 The modification of peptidyl-proline to form trans-2,3-cis-3,4-dihydroxy-L-proline. GO:0018187 molybdenum incorporation via L-cysteinyl molybdopterin guanine dinucleotide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018187 RESID:AA0281 The incorporation of molybdenum into a protein by L-cysteinyl molybdopterin guanine dinucleotide. UBERON:0015083 proximal tarsal bone pre-cartilage condensation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015083 A proximal tarsal endochondral element that is composed primarily of a pre-cartilage condensation. UBERON:0015082 proximal tarsal cartilage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015082 A proximal tarsal endochondral element that is composed primarily of cartilage tissue. GO:0102023 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0102023 GO:0102022 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0102022 GO:0102025 ABC-type thiosulfate transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102025 EC:7.3.2.3|RHEA:29871|MetaCyc:ABC-7-RXN ATPase-coupled thiosulfate transmembrane transporter activity|thiosulphate ABC transporter activity|thiosulfate transmembrane-transporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + thiosulfate(out) = ADP + phosphate + thiosulfate(in). GO:0102027 S-adenosylmethionine:2-demethylquinol-8 methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102027 RHEA:30063|EC:2.1.1.163|MetaCyc:ADOMET-DMK-METHYLTRANSFER-RXN Catalysis of the reaction: 2-demethylmenaquinol-8 + S-adenosyl-L-methionine <=> menaquinol-8 + H+ + S-adenosyl-L-homocysteine. GO:0102026 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0102026 GO:0102029 D-lactate dehydrogenase (quinone) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102029 MetaCyc:DLACTDEHYDROGFAD-RXN|RHEA:51468|EC:1.1.5.12 Catalysis of the reaction: (R)-lactate + an ubiquinone = pyruvate + an ubiquinol. GO:0102028 cystathionine gamma-synthase activity (acts on O-phosphohomoserine) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102028 EC:2.5.1.48|MetaCyc:CYSPH-RXN Catalysis of the reaction: L-cysteine + O-phosphonato-L-homoserine = L-cystathionine + hydrogenphosphate. UBERON:0015081 proximal tarsal endochondral element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015081 proximal tarsal A proximal mesopodial endochondral element that is part of a hindlimb. UBERON:0015080 proximal carpal bone pre-cartilage condensation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015080 A proximal carpal endochondral element that is composed primarily of a pre-cartilage condensation. GO:0018197 peptidyl-aspartic acid modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018197 The modification of peptidyl-aspartic acid. GO:0018196 peptidyl-asparagine modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018196 The modification of peptidyl-asparagine. GO:0018199 peptidyl-glutamine modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018199 The modification of peptidyl-glutamine. GO:0018198 peptidyl-cysteine modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018198 The modification of peptidyl-cysteine. GO:0018171 peptidyl-cysteine oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018171 RESID:AA0205|RESID:AA0262 The oxidation of peptidyl-cysteine to peptidyl-L-cysteine sulfinic acid or peptidyl-L-cysteine sulfenic acid. GO:0018170 C-terminal peptidyl-polyglutamic acid amidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018170 RESID:AA0261 The formation of a C-terminal peptidyl-polyglutamic acid to form a peptidyl-N-L-glutamyl-poly-L-glutamic acid C-terminus. GO:0018173 peptidyl-1-thioglycine biosynthetic process from peptidyl-glycine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018173 RESID:AA0265 peptidyl-1-thioglycine anabolism from peptidyl-glycine|peptidyl-1-thioglycine synthesis from peptidyl-glycine|peptidyl-1-thioglycine formation from peptidyl-glycine The chemical reactions and pathways resulting in the formation of peptidyl-1-thioglycine from other compounds, including peptidyl-glycine. GO:0018172 peptidyl-L-3',4',5'-trihydroxyphenylalanine biosynthetic process from peptidyl-tyrosine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018172 RESID:AA0263 peptidyl-L-3',4',5'-trihydroxyphenylalanine synthesis from peptidyl-tyrosine|peptidyl-L-3',4',5'-trihydroxyphenylalanine anabolism from peptidyl-tyrosine|peptidyl-L-3',4',5'-trihydroxyphenylalanine formation from peptidyl-tyrosine The modification of protein tyrosine to peptidyl-L-3',4',5'-dihydroxyphenylalanine. GO:0018168 protein-phycoerythrobilin linkage via S-phycoerythrobilin-L-cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018168 RESID:AA0132 The linkage of the chromophore phycoerythrobilin to phycoerythrocyanin via S-phycoerythrobilin-L-cysteine. GO:0018167 protein-phycoerythrobilin linkage via phycoerythrobilin-bis-L-cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018167 RESID:AA0259 The linkage of the chromophore phycoerythrobilin to phycoerythrin via phycoerythrobilin-bis-L-cysteine. GO:0018169 ribosomal S6-glutamic acid ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018169 Catalysis of the posttranslational transfer of one or more glutamic acid residues to the C-terminus of ribosomal protein S6. GO:0018164 protein-DNA covalent cross-linking via peptidyl-threonine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018164 RESID:AA0255 DNA-protein covalent cross-linking via peptidyl-threonine The formation of a covalent cross-link between DNA and a peptidyl-threonine residue by the formation of O-(phospho-5'-DNA)-L-threonine. GO:0018163 protein-DNA covalent cross-linking via the 5'-end to peptidyl-tyrosine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018163 RESID:AA0254 DNA-protein covalent cross-linking via the 5' end to peptidyl-tyrosine The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-5'-DNA)-L-tyrosine. GO:0018166 C-terminal protein-tyrosinylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018166 RESID:AA0257 The ATP-dependent addition of a tyrosine residue to the C-terminus of a protein; typically the addition of tyrosine to the C-terminus of detyrosinated alpha-tubulin by the enzyme tubulin-tyrosine ligase. GO:0018165 peptidyl-tyrosine uridylylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018165 RESID:AA0256 The uridylylation of peptidyl-tyrosine to form peptidyl-O4'-(phospho-5'-uridine)-L-tyrosine, found in glutamine synthetase. GO:0018182 protein-heme linkage via 3'-L-histidine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018182 RESID:AA0276 protein-haem linkage via 3'-L-histidine The covalent linkage of heme and a protein via 3'-L-histidine (otherwise known as pi-heme-histidine, pros-heme-histidine). GO:0018181 peptidyl-arginine C5-methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018181 RESID:AA0272 peptidyl-arginine 5-methylation The methylation of peptidyl-arginine on the carbon 5 (C5) residue to form peptidyl-5-methyl-L-arginine. GO:0018184 protein polyamination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018184 protein amino acid polyamination The modification of a protein amino acid by polyamination. GO:0018183 obsolete enzyme active site formation via S-selenyl-L-cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018183 enzyme active site formation via S-selenyl-L-cysteine OBSOLETE. The transient selenylation of peptidyl-cysteine to form S-selenyl-L-cysteine. GO:0018180 protein desulfurization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018180 protein amino acid desulfurization|protein amino acid desulphurisation|protein amino acid desulfurisation|protein amino acid desulphurization The removal of a sulfur group from a protein amino acid. GO:0033799 myricetin 3'-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033799 MetaCyc:RXN-8451|MetaCyc:RXN-13912|EC:2.1.1.267;|RHEA:25629|KEGG_REACTION:R06815 S-adenosyl-L-methionine:myricetin O-methyltransferase activity|CrCOMT2|myricetin 3-O-methyltransferase activity|flavonoid 3',5'-O-dimethyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + myricetin = S-adenosyl-L-homocysteine + laricitrin. GO:0033790 hydroxymethylfurfural reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033790 Catalysis of the reaction: 5-hydroxymethylfurfural + NAD(P)H + H+ = 2,5-bis-hydroxymethylfuran + NAD(P)+. GO:0033798 thyroxine 5-deiodinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033798 RHEA:18897|EC:1.21.99.3|MetaCyc:1.97.1.11-RXN diiodothyronine 5'-deiodinase activity|acceptor:3,3',5'-triiodo-L-thyronine oxidoreductase (iodinating) activity|iodothyronine inner ring monodeiodinase activity|type III iodothyronine deiodinase activity|inner ring-deiodinating pathway|iodothyronine 5-deiodinase activity Catalysis of the reaction: 3,3',5'-triiodo-L-thyronine + iodide + A + H+ = L-thyroxine + AH2. GO:0018179 obsolete peptidyl-cysteine desulfurization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018179 RESID:AA0269 peptidyl-cysteine desulphurization|peptidyl-cysteine desulfurization OBSOLETE. The desulfurization of peptidyl-L-cysteine to yield L-alanine and elemental sulfur; peptidyl-L-cysteine persulfide is an intermediate. GO:0033797 selenate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033797 KEGG_REACTION:R07229|EC:1.97.1.9|RHEA:14031|UM-BBD_reactionID:r0828|MetaCyc:RXN0-2101 selenite:reduced acceptor oxidoreductase activity Catalysis of the reaction: 2 e(-) + 2 H(+) + selenate = H(2)O + selenite. GO:0018178 peptidyl-threonine adenylylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018178 RESID:AA0267 peptidyl-threonine adenylation The adenylylation of peptidyl-threonine to form peptidyl-O-(phospho-5'-adenosine)-L-threonine. GO:0033796 sulfur reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033796 RHEA:35591|EC:1.12.98.4|MetaCyc:RXN-8269|MetaCyc:1.97.1.3-RXN (donor):sulfur oxidoreductase activity|sulphur reductase activity Catalysis of the reduction of elemental sulfur or polysulfide to hydrogen sulfide. GO:0033795 betaine reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033795 EC:1.21.4.4|RHEA:11848 acetyl-phosphate trimethylamine:thioredoxin disulfide oxidoreductase (N,N,N-trimethylglycine-forming) activity Catalysis of the reaction: acetyl phosphate + trimethylamine + thioredoxin disulfide = N,N,N-trimethylglycine + phosphate + thioredoxin. GO:0018175 protein nucleotidylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018175 protein amino acid nucleotidylation The addition of a nucleotide to a protein amino acid. GO:0033794 sarcosine reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033794 EC:1.21.4.3|RHEA:12825 acetyl-phosphate methylamine:thioredoxin disulfide oxidoreductase (N-methylglycine-forming) activity Catalysis of the reaction: acetyl phosphate + methylamine + thioredoxin disulfide = N-methylglycine + phosphate + thioredoxin. GO:0018174 protein-heme P460 linkage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018174 RESID:AA0266|RESID:AA0271 protein-haem P460 linkage The linkage of protein to heme P460. GO:0033793 aureusidin synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033793 2',4,4',6'-tetrahydroxychalcone:oxygen oxidoreductase activity Catalysis of the reactions: 2',4,4',6'-tetrahydroxychalcone + O2 = aureusidin + H2O, and 2',3,4,4',6'-pentahydroxychalcone + 1/2 O2 = aureusidin + H2O. GO:0018177 protein uridylylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018177 protein amino acid uridylylation The addition of phospho-uridine to a protein amino acid. GO:0033792 bile-acid 7alpha-dehydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033792 MetaCyc:RXN-8659|MetaCyc:RXN-8658|EC:1.17.99.5 bile acid 7-dehydroxylase activity|deoxycholate:NAD+ oxidoreductase activity|cholate 7alpha-dehydroxylase activity|deoxycholate:FAD oxidoreductase (7alpha-dehydroxylating) activity|7alpha-dehydroxylase activity Catalysis of the reactions: deoxycholate + FAD + H2O = cholate + FADH2, and lithocholate + FAD + H2O = chenodeoxycholate + FADH2. GO:0033791 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033791 RHEA:15733|MetaCyc:1.17.99.3-RXN|EC:1.17.99.3 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA oxidase activity|THC-CoA oxidase activity|THCA-CoA oxidase activity|(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA:acceptor 24-oxidoreductase (24R-hydroxylating) activity|trihydroxycoprostanoyl-CoA oxidase activity|3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate 24-hydroxylase activity Catalysis of the reaction: (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + H2O + acceptor = (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA + reduced acceptor. GO:0018176 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018176 GO:0018151 peptide cross-linking via L-histidyl-L-tyrosine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018151 The modification of peptidyl-histidine and peptidyl-tyrosine to form a protein cross-link. GO:0018150 peptide cross-linking via 3-(3'-L-histidyl)-L-tyrosine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018150 RESID:AA0250 The modification of peptidyl-histidine and peptidyl-tyrosine to form a 3-(3'-L-histidyl)-L-tyrosine protein cross-link. GO:0033789 phenylacetyl-CoA dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033789 MetaCyc:1.17.5.1-RXN|RHEA:15705|EC:1.17.5.1|KEGG_REACTION:R07222 phenylacetyl-CoA:quinone oxidoreductase activity|phenylacetyl-CoA:acceptor oxidoreductase activity Catalysis of the reaction: 2 1,4-benzoquinone + H(2)O + phenylacetyl-CoA = 2 hydroquinone + phenylglyoxylyl-CoA. GO:0033788 leucoanthocyanidin reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033788 MetaCyc:RXN-1484|RHEA:10616|EC:1.17.1.3 (2R,3S)-catechin:NADP+ 4-oxidoreductase activity|leucocyanidin reductase activity Catalysis of the reaction: (2R,3S)-catechin + NADP+ + H2O = 2,3-trans-3,4-cis-leucocyanidin + NADPH + H+. GO:0018149 peptide cross-linking biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018149 The formation of a covalent cross-link between or within protein chains. GO:0018146 keratan sulfate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018146 RESID:AA0247 keratan sulfate anabolism|keratan sulfate synthesis|keratan sulfate formation|keratan sulfate biosynthesis|keratan sulphate biosynthetic process|keratan sulphate biosynthesis The chemical reactions and pathways resulting in the formation of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues. GO:0033787 cyanocobalamin reductase (cyanide-eliminating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033787 Reactome:R-HSA-3149519|KEGG_REACTION:R02999|EC:1.16.1.6|RHEA:16113|MetaCyc:1.6.99.12-RXN cob(I)alamin, cyanide:NADP+ oxidoreductase activity|cyanocobalamin reductase (NADPH, cyanide-eliminating) activity|NADPH:cyanocob(III)alamin oxidoreductase (cyanide-eliminating) activity|NADPH2:cyanocob(III)alamin oxidoreductase (cyanide-eliminating) activity|cyanocobalamin reductase activity|cyanocobalamin reductase (NADPH; CN-eliminating) activity Catalysis of the reaction: cob(I)alamin + hydrogen cyanide + NADP(+) = cyanocob(III)alamin + H(+) + NADPH. GO:0033786 heptose-1-phosphate adenylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033786 MetaCyc:RXN0-4342|RHEA:27465 D-beta-D-heptose 1-phosphate adenylyltransferase activity|heptose 1-phosphate adenyltransferase activity Catalysis of the reaction: D-beta-D-heptose-1-phosphate + ATP = ADP-D-glycero-D-manno-heptose. GO:0018145 protein-DNA covalent cross-linking via peptidyl-serine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018145 RESID:AA0246 DNA-protein covalent cross-linking via peptidyl-serine The formation of a covalent cross-link between DNA and a peptidyl-serine residue by the formation of O-(phospho-5'-DNA)-L-serine. GO:0018148 RNA-protein covalent cross-linking via peptidyl-tyrosine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018148 RESID:AA0249 The formation of a covalent cross-link between RNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-5'-RNA)-L-tyrosine. CHEBI:138483 cis-3,4-dialkyloxetan-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138483 GO:0033785 heptose 7-phosphate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033785 MetaCyc:RXN0-4341|RHEA:27473|EC:2.7.1.- D-alpha,beta-D-heptose 7-phosphate 1-kinase activity Catalysis of the reaction: D-alpha,beta-D-heptose-7-phosphate + ATP = D-beta-D-heptose-1,7-bisphosphate + ADP. GO:0033784 senecionine N-oxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033784 MetaCyc:1.14.13.101-RXN|EC:1.14.13.101|RHEA:11420|KEGG_REACTION:R07373 senecionine,NADPH:oxygen oxidoreductase (N-oxide-forming) activity|SNO|senecionine monooxygenase (N-oxide-forming) activity Catalysis of the reaction: H(+) + NADPH + O(2) + senecionine = H(2)O + NADP(+) + senecionine N-oxide. CHEBI:138482 N(2)-[(3R)-hydroxy-acyl]-L-ornithine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138482 GO:0018147 molybdenum incorporation via L-selenocysteinyl molybdenum bis(molybdopterin guanine dinucleotide) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018147 RESID:AA0248 The incorporation of molybdenum into a protein via L-selenocysteinyl molybdenum bis(molybdopterin guanine dinucleotide). GO:0033783 25-hydroxycholesterol 7alpha-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033783 RHEA:19041|MetaCyc:RXN-7981|MetaCyc:RXN-7980|EC:1.14.14.29 CYP7B1|25-hydroxycholesterol 7alpha-monooxygenase activity|CYP7B1 oxysterol 7alpha-hydroxylase activity|cholest-5-ene-3beta,25-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) activity Catalysis of the reactions: cholest-5-ene-3beta,25-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,25-triol + NADP+ + H2O, and cholest-5-ene-3beta,27-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,27-triol + NADP+ + H2O. GO:0018142 protein-DNA covalent cross-linking biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018142 DNA-protein covalent cross-linking The formation of a covalent cross-link between DNA and a protein. GO:0033782 24-hydroxycholesterol 7alpha-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033782 RHEA:16093|EC:1.14.13.99|KEGG_REACTION:R07208|MetaCyc:1.14.13.99-RXN 24-hydroxycholesterol 7alpha-monooxygenase activity|CYP39A1 oxysterol 7alpha-hydroxylase activity|(24R)-cholest-5-ene-3beta,24-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) activity|CYP39A1 Catalysis of the reaction: (24R)-cholest-5-ene-3beta,24-diol + H(+) + NADPH + O(2) = (24R)-7alpha,24-dihydroxycholesterol + H(2)O + NADP(+). GO:0018141 peptide cross-linking via L-lysine thiazolecarboxylic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018141 RESID:AA0245 The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl lysine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation. GO:0033781 cholesterol 24-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033781 EC:1.14.14.25|RHEA:22716|KEGG_REACTION:R07207|MetaCyc:1.14.13.98-RXN|Reactome:R-HSA-192061 CYP46A1|cholesterol 24S-hydroxylase activity|cytochrome P450 46A1|CYP46|cholesterol,NADPH:oxygen oxidoreductase (24-hydroxylating) activity|cholesterol 24-monooxygenase activity Catalysis of the reaction: cholesterol + H(+) + NADPH + O(2) = (24S)-24-hydroxycholesterol + H(2)O + NADP(+). GO:0018144 RNA-protein covalent cross-linking biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018144 The formation of a covalent cross-link between RNA and a protein. GO:0033780 taurochenodeoxycholate 6alpha-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033780 MetaCyc:RXN-7977|EC:1.14.13.97|RHEA:23644 CYP4A21|taurochenodeoxycholate 6alpha-monooxygenase activity|taurochenodeoxycholate,NADPH:oxygen oxidoreductase (6alpha-hydroxylating) activity|CYP3A4 Catalysis of the reactions: taurochenodeoxycholate + NADPH + H+ + O2 = taurohyocholate + NADP+ + H2O, and lithocholate + NADPH + H+ + O2 = hyodeoxycholate + NADP+ + H2O. GO:0018143 nucleic acid-protein covalent cross-linking biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018143 The formation of a covalent cross-link between a nucleic acid and a protein. GO:0018160 peptidyl-pyrromethane cofactor linkage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018160 RESID:AA0252 peptidyl-pyrromethane cofactor linkage via dipyrrolylmethanemethyl-L-cysteine|dipyrromethane cofactor binding The covalent binding of a pyrromethane (dipyrrin) cofactor to protein via the sulfur atom of cysteine forming dipyrrolylmethanemethyl-L-cysteine. GO:0018162 peptide cross-linking via S-(2-aminovinyl)-3-methyl-D-cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018162 RESID:AA0253 The formation of a cross-link between peptidyl-cysteine and peptidyl-threonine via the formation of S-(2-aminovinyl)-3-methyl-D-cysteine. GO:0018161 dipyrrin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018161 dipyrromethane biosynthesis|dipyrromethane biosynthetic process|dipyrrin biosynthesis|dipyrrin anabolism|dipyrrin synthesis|dipyrrin formation The chemical reactions and pathways resulting in the formation of dipyrrins (pyrromethanes), compounds containing two pyrrole rings linked through a methine, -CH=, group. GO:0033779 5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033779 KEGG_REACTION:R07204|MetaCyc:1.14.13.96-RXN|RHEA:15261|EC:1.14.14.139 cytochrome P450 8B1|5beta-cholestane-3alpha,7alpha-diol 12alpha-monooxygenase activity|sterol 12alpha-hydroxylase activity|5beta-cholestane-3alpha,7alpha-diol,NADPH:oxygen oxidoreductase (12alpha-hydroxylating) activity|CYP8B1 Catalysis of the reaction: 5beta-cholestane-3alpha,7alpha-diol + H(+) + NADPH + O(2) = 5beta-cholestane-3alpha,7alpha,12alpha-triol + H(2)O + NADP(+). GO:0033778 7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033778 KEGG_REACTION:R04826|RHEA:10504|MetaCyc:1.14.13.95-RXN|Reactome:R-HSA-192157|Reactome:R-HSA-193845|Reactome:R-HSA-193709|EC:1.14.13.95 CYP12|7alpha-hydroxycholest-4-en-3-one,NADPH:oxygen oxidoreductase (12alpha-hydroxylating) activity|sterol 12alpha-hydroxylase activity|HCO 12alpha-hydroxylase activity|7alpha-hydroxy-4-cholesten-3-one 12alpha-monooxygenase activity Catalysis of the reaction: 7alpha-hydroxycholest-4-en-3-one + H(+) + NADPH + O(2) = 7alpha,12alpha-dihydroxycholest-4-en-3-one + H(2)O + NADP(+). GO:0033777 lithocholate 6beta-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033777 RHEA:18857|KEGG_REACTION:R07203|MetaCyc:1.14.13.94-RXN|EC:1.14.14.138 lithocholate,NADPH:oxygen oxidoreductase (6beta-hydroxylating) activity|6beta-hydroxylase activity|lithocholate 6beta-monooxygenase activity|CYP3A10|cytochrome P450 3A10/lithocholic acid 6beta-hydroxylase activity Catalysis of the reaction: H(+) + lithocholate + NADPH + O(2) = 6-beta-hydroxylithocholate + H(2)O + NADP(+). GO:0033776 phenylacetone monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033776 RHEA:10124|KEGG_REACTION:R07201|MetaCyc:1.14.13.92-RXN|EC:1.14.13.92 phenylacetone,NADPH:oxygen oxidoreductase activity|PAMO Catalysis of the reaction: H(+) + NADPH + O(2) + phenylacetone = benzyl acetate + H(2)O + NADP(+). GO:0018157 peptide cross-linking via an oxazole or thiazole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018157 peptide heterocycle formation|peptide heterocycle biosynthesis|peptide heterocycle synthesis|peptide heterocycle biosynthetic process The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl glycine, or peptidyl cysteine-peptidyl glycine cross-link by the condensation of the serine hydroxyl or cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation. GO:0033775 deoxysarpagine hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033775 RHEA:14237|MetaCyc:1.14.13.91-RXN|EC:1.14.14.136|KEGG_REACTION:R05828 DOSH|10-deoxysarpagine,NADPH:oxygen oxidoreductase (10-hydroxylating) activity Catalysis of the reaction: 10-deoxysarpagine + H(+) + NADPH + O(2) = H(2)O + NADP(+) + sarpagine. GO:0018156 peptide cross-linking via (2S,3S,6R)-3-methyl-lanthionine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018156 RESID:AA0112 The formation of a protein-protein cross-link between peptidyl-threonine and peptidyl-cysteine by the synthesis of (2S,3S,6R)-3-methyl-lanthionine (3-methyl-L-lanthionine). GO:0018159 peptidyl-methionine oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018159 RESID:AA0251 The oxidation of peptidyl-L-methionine to peptidyl-L-methionine sulfone. GO:0033774 basal labyrinth biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033774 A region in the lower half of some cells formed from extensive infoldings of the basal plasma membrane; includes cytoplasm adjacent to the infolded membrane. GO:0033773 isoflavone 2'-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033773 MetaCyc:ISOFLAVONE-2-HYDROXYLASE-RXN|EC:1.14.13.89 CYP81E1|isoflavone 2'-monooxygenase activity|CYP Ge-3|isoflavone,NADPH:oxygen oxidoreductase (2'-hydroxylating) activity Catalysis of the reaction: an isoflavone + NADPH + H+ + O2 = a 2'-hydroxyisoflavone + NADP+ + H2O. GO:0018158 protein oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018158 protein amino acid oxidation The modification of a protein amino acid by oxidation. GO:0033772 flavonoid 3',5'-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033772 RHEA:55448|MetaCyc:RXN-8671|MetaCyc:RXN-7783|EC:1.14.14.81 F3',5'H|F3'5'H|flavanone,NADPH:oxygen oxidoreductase activity Catalysis of the reactions: a flavanone + NADPH + H+ + O2 = a 3'-hydroxyflavanone + NADP+ + H2O, and a 3'-hydroxyflavanone + NADPH + H+ + O2 = a 3',5'-dihydroxyflavanone + NADP+ + H2O. GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018153 RESID:AA0124 The formation of an isopeptide cross-link between peptidyl-lysine and peptidyl-glutamine to produce N6-(L-isoglutamyl)-L-lysine. GO:0033771 licodione synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033771 MetaCyc:1.14.13.87-RXN|RHEA:15697|KEGG_REACTION:R07198|EC:1.14.14.140 liquiritigenin,NADPH:oxygen oxidoreductase (licodione-forming) activity|(2S)-flavanone 2-hydroxylase activity Catalysis of the reaction: H(+) + liquiritigenin + NADPH + O(2) = H(2)O + licodione + NADP(+). GO:0018152 peptide cross-linking via 3'-(1'-L-histidyl)-L-tyrosine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018152 RESID:AA0270 The modification of peptidyl-histidine and peptidyl-tyrosine to form a 3'-(1'-L-histidyl)-L-tyrosine protein cross-link. GO:0018155 peptide cross-linking via sn-(2S,6R)-lanthionine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018155 RESID:AA0111 The formation of a protein-protein cross-link between peptidyl-serine and peptidyl-cysteine by the synthesis of sn-(2S,6R)-lanthionine (meso-lanthione). GO:0033770 2-hydroxyisoflavanone synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033770 RHEA:14897|EC:1.14.13.86|MetaCyc:RXN-7750 2-HIS|apigenin,NADPH:oxygen oxidoreductase (isoflavanone-forming) activity Catalysis of the reaction: apigenin + 2 NADPH + 2 H+ + O2 = 2-hydroxy-2,3-dihydrogenistein + 2 NADP+ + H2O. GO:0018154 peptide cross-linking via (2R,6R)-lanthionine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018154 RESID:AA0110 The formation of a protein-protein cross-link between peptidyl-serine and peptidyl-cysteine by the synthesis of (2R,6R)-lanthionine (L-lanthionine). UBERON:0015153 medial gland of ocular region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015153 Harderian gland|medial orbital gland|medial ocular gland A gland that is located in the ocular region, nearer the inner canthi. Typically associated with or part of the nictitating membrane, when present GO:0102072 3-oxo-cis-Delta9-hexadecenoyl-[acp] reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102072 MetaCyc:RXN-10659 Catalysis of the reaction: NADP + a 3R-hydroxy cis Delta9-hexadecenoyl-[acp] <=> NADPH + H+ + a 3-oxo-cis-Delta9-hexadecenoyl-[acp]. GO:0102071 9,10-epoxy-18-hydroxystearate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102071 MetaCyc:RXN-1065 Catalysis of the reaction: 9,10-epoxy-18-hydroxystearate + H2O <=> 9,10,18-trihydroxystearate. UBERON:0015152 gland of ocular region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015152 ocular gland|orbital gland A gland that is typically found in or near the orbital region, in or around either the medial or lateral canthi, and is typically associated with secretions onto the eyeball or associated ducts. Includes the Harderian, nictitans and lacrimal glands. PO:0005656 portion of secretory tissue biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0005656 分泌組織の一部 (Japanese, exact)|porción del tejido secretor (Spanish, exact)|gland (related) A portion of plant tissue (PO:0009007) that form specialized structures producing a secretion. UBERON:0015155 conjunctival space biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015155 conjunctival sac cavity|subbrillar space|subconjunctival space|cavity of conjunctival sac A anatomical space that is enclosed by a conjunctiva. GO:0102074 OPC6-trans-2-enoyl-CoA hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102074 MetaCyc:RXN-10704 Catalysis of the reaction: OPC6-3-hydroxyacyl-CoA <=> OPC6-trans-2-enoyl-CoA + H2O. CHEBI:58939 2-(1-hydroxyethyl)thiamine diphosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58939 UBERON:0015154 lateral gland of orbital region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015154 lateral ocular gland|lateral orbital gland A gland that is located in or around the ocular region, nearer the outer canthi. GO:0102073 OPC8-trans-2-enoyl-CoA hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102073 MetaCyc:RXN-10697 Catalysis of the reaction: OPC8-3-hydroxyacyl-CoA <=> OPC8-trans-2-enoyl-CoA + H2O. CHEBI:58938 thiamine(1+) triphosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58938 GO:0102076 beta,beta-carotene-9',10'-cleaving oxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102076 EC:1.13.11.71|RHEA:26389|MetaCyc:RXN-10741 Catalysis of the reaction: beta-carotene + O2 <=> 10'-apo-beta-carotenal + beta-ionone. CHEBI:58937 thiamine(1+) diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58937 GO:0102075 OPC4-trans-2-enoyl-CoA hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102075 MetaCyc:RXN-10705 Catalysis of the reaction: OPC4-3-hydroxyacyl-CoA <=> OPC4-trans-2-enoyl-CoA + H2O. CHEBI:58936 2,4-dihydroxyhept-2-enedioate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58936 UBERON:0015151 Harderian gland duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015151 duct of Harderian gland|duct of Harder's gland|Harderian duct A duct that is part of a Harderian gland. opens into the conjunctival sac at the base of the nictitating membrane. GO:0102078 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0102078 CHEBI:58935 2,4-diazaniumylpentanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58935 UBERON:0015150 dorsal hair biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015150 back hair|dorsal coat hair|hair of back A strand of hair that is part of a dorsum. GO:0102077 oleamide hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102077 RHEA:26506|EC:3.5.1.99|MetaCyc:RXN-10756 Catalysis of the reaction: oleamide + H2O <=> oleate + ammonium. CHEBI:19327 2-hydroxy-6-(2-hydroxyphenoxy)-6-oxo-cis,cis-hexa-2,4-dienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_19327 CHEBI:58934 2,2'-iminodipropanoate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58934 CHEBI:58933 propanoyl phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58933 CHEBI:19324 2,3-bisphosphoglycerate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_19324 CHEBI:58931 oxalatosuccinate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58931 CHEBI:58930 16-methoxytabersoninium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58930 GO:0102081 homotaurine:2-oxoglutarate aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102081 MetaCyc:RXN-10822 Catalysis of the reaction: homotaurine + 2-oxoglutarate(2-) <=> 3-sulfopropanal + L-glutamate(1-). GO:0102080 phenylacetyl-coenzyme A:glycine N-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102080 RHEA:27850|MetaCyc:RXN-10821|EC:2.3.1.192 Catalysis of the reaction: phenylacetyl-CoA + glycine <=> H+ + phenylacetylglycine + coenzyme A. GO:0102083 7,8-dihydromonapterin aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102083 MetaCyc:RXN-10857 Catalysis of the reaction: 7,8-dihydromonapterin <=> glycolaldehyde + 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol. UBERON:0015142 falciform fat biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015142 falciform fat depot|falciform ligament fat pad A large fat pad that is located at the base of the abdominal wall, in the falciform ligament of the liver. GO:0102082 demethylrebeccamycin--D-glucose O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102082 MetaCyc:RXN-10847|RHEA:27353|EC:2.1.1.164 Catalysis of the reaction: 4'-demethylrebeccamycin + S-adenosyl-L-methionine <=> H+ + rebeccamycin + S-adenosyl-L-homocysteine. PO:0005645 leaf mesophyll biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0005645 葉の葉肉 (Japanese, exact) (exact)|foliage leaf mesophyll (related)|leaf parenchyma (related)|mesófilo de la hoja (Spanish, exact) The chloroplast-containing, photosynthetic parenchymatous tissue situated between the two epidermal layers of the foliage leaf. UBERON:0015144 autopod hair biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015144 hair of hand/foot|paw hair|hand/foot hair A strand of hair that is part of a autopod region. CHEBI:58929 N(4)-acetyl-L-2,4-diaminobutyric acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58929 GO:0102085 N-(4-aminobenzoyl)-L-glutamate synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102085 MetaCyc:RXN-10884 Catalysis of the reaction: 4-aminobenzoate + L-glutamate + ATP <=> H+ + p-aminobenzoyl glutamate + AMP + diphosphoric acid. GO:0102084 L-dopa O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102084 EC:2.1.1.6|MetaCyc:RXN-10870 Catalysis of the reaction: L-dopa + S-adenosyl-L-methionine <=> 3-O-methyldopa + S-adenosyl-L-homocysteine + H+. UBERON:0015143 mesenteric fat pad biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015143 mesenteric fat depot Encapsulated adipose tissue associated with the mesentery CHEBI:58928 N-formimidoyl-L-glutamate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58928 CHEBI:83905 UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83905 GO:0102087 N-benzoyl-L-glutamate synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102087 MetaCyc:RXN-10886 Catalysis of the reaction: benzoate + L-glutamate + ATP <=> H+ + N-benzoyl-L-glutamate + AMP + diphosphoric acid. CHEBI:58927 L-lupinic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58927 GO:0102086 N-vanillate-L-glutamate synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102086 MetaCyc:RXN-10885 Catalysis of the reaction: vanillate + L-glutamate(1-) + ATP <=> H+ + N-vanillate-L-glutamate + AMP + diphosphoric acid. CHEBI:83903 UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-gamma-glutamyl-L-lysinate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83903 PO:0005648 palisade mesophyll biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0005648 柵状葉肉 (Japanese, exact)|palisade parenchyma (related)|mesófilo en empalizada (Spanish, exact) Parenchyma containing closely packed elongated chlorenchymatous cells oriented perpendicular to the leaf surface and which are active in photosynthesis. GO:0102089 dehydroscoulerine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102089 MetaCyc:RXN-10888 Catalysis of the reaction: (S)-scoulerine + O2 = dehydroscoulerine + hydrogen peroxide + H+. CHEBI:58925 kaempferide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58925 GO:0102088 N-(4-hydroxybenzoyl)-L-glutamate synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102088 MetaCyc:RXN-10887 Catalysis of the reaction: 4-hydroxybenzoic acid + L-glutamate + ATP <=> H+ + N-(4-hydroxybenzoyl)-L-glutamate + AMP + diphosphoric acid. CHEBI:58924 isopimarate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58924 UBERON:0015149 ventral hair biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015149 ventral coat hair A strand of hair that is part of a ventrum. CHEBI:83900 UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83900 CHEBI:10986 (R)-4'-phosphonatopantothenate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_10986 UBERON:0015146 manus hair biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015146 hair of hand|front paw hair|hand hair A strand of hair that is part of a manus. UBERON:0015145 pes hair biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015145 hind foot hair|hind paw hair|hair of foot|foot hair A strand of hair that is part of a pes. UBERON:0015148 tail hair biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015148 A strand of hair that is part of a tail. UBERON:0015147 pinna hair biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015147 ear hair A strand of hair that is part of a pinna. CHEBI:10980 (R)-3-(4-hydroxyphenyl)lactate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_10980 CHEBI:10983 (R)-3-hydroxybutyrate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_10983 CHEBI:58923 lipoyl-AMP(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58923 CHEBI:58922 Ile(5)-angiotensin II (1-7) dizwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58922 CHEBI:58921 N-acyl-L-homoserinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58921 CHEBI:58920 (S)-piperazine-2-carboxylic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58920 GO:0102090 adrenaline O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102090 MetaCyc:RXN-10909 Catalysis of the reaction: (R)-adrenaline(1+) + S-adenosyl-L-methionine <=> metanephrine + S-adenosyl-L-homocysteine + H+. GO:0102092 5-diphosphoinositol pentakisphosphate 3-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102092 EC:2.7.4.24|MetaCyc:RXN-10979 Catalysis of the reaction: 5-diphospho-1D-myo-inositol pentakisphosphate + ATP = 3,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + ADP. GO:0102091 phosphatidylinositol-5-phosphate 5-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102091 MetaCyc:RXN-10962 Catalysis of the reaction: H2O + a 1-phosphatidyl-1D-myo-inositol 5-phosphate = hydrogenphosphate + an L-1-phosphatidyl-inositol. GO:0102094 S-adenosylmethionine:2-demethylmenaquinol methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102094 RHEA:26466|EC:2.1.1.163|MetaCyc:RXN-11046 Catalysis of the reaction: S-adenosyl-L-methionine + a demethylmenaquinol <=> S-adenosyl-L-homocysteine + H+ + a menaquinol. CHEBI:19351 (2,4-dichlorophenoxy)acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_19351 CHEBI:58919 (S)-piperazin-4-ium-2-carboxamide(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58919 UBERON:0015130 connective tissue of prostate gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015130 connective tissue of prostate A portion of connective tissue that is part of a prostate gland. GO:0102093 acrylate:acyl-coA CoA transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102093 MetaCyc:RXN-10985 Catalysis of the reaction: acryloyl-CoA + H2O <=> acrylate + coenzyme A + H+. GO:0102096 decaprenyl-N-acetyl-alpha-D-glucosaminyl-pyrophosphate:dTDP-alpha-L-rhamnose rhamnosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102096 MetaCyc:RXN-11070|RHEA:34487|EC:2.4.1.289 Catalysis of the reaction: dTDP-6-deoxy-beta-L-mannose + N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol <=> dTDP(3-) + alpha-L-Rhap-(1->3)-alpha-D-GlcpNAc-1-diphospho-trans,octacis-decaprenol + H+. CHEBI:58918 beta-alaninium amide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58918 CHEBI:58917 (R)-piperazine-2-carboxylic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58917 GO:0102098 D-galacturonate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102098 MetaCyc:RXN-11151|RHEA:26345|EC:1.1.1.365 Catalysis of the reaction: L-galactonate + NADP = aldehydo-D-galacturonate + NADPH + H+. CHEBI:58916 (R)-piperazin-4-ium-2-carboxamide(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58916 CHEBI:83916 omega-hydroxyphytanate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83916 CHEBI:58915 (2E)-but-2-ene-1,2,3-tricarboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58915 GO:0102097 (22S)-22-hydroxy-5alpha-campestan-3-one C-23 hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102097 RHEA:27325|EC:1.14.14.147|MetaCyc:RXN-11101 Catalysis of the reaction: (5alpha,22S,24R)-22-hydroxyergostan-3-one + O2 + NADPH + H+ <=> 3-dehydro-6-deoxoteasterone + NADP + H2O. CHEBI:58914 all-trans-polyprenyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58914 CHEBI:83914 omega-hydroxy-15-methylpalmitate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83914 GO:0102099 FAD-dependent urate hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102099 MetaCyc:RXN-11186|RHEA:27329|EC:1.14.13.113 Catalysis of the reaction: 7,9-dihydro-1H-purine-2,6,8(3H)-trione + NADH + H+ + O2 <=> 5-hydroxyisouric acid + NAD + H2O. CHEBI:58913 delphinidin-5-olate 3-O-(6''-O-carboxylatoacetyl)-beta-D-glucoside-3'-O-beta-D-glucoside(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58913 CHEBI:83912 N(6)-(UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-gamma-glutamyl)-D-lysine(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83912 CHEBI:58912 ternatin C5(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58912 CHEBI:58911 delphinidin-5-olate 3-O-(6''-O-carboxylatoacetyl)-beta-D-glucoside(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58911 CHEBI:58910 thyroxine sulfate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58910 CHEBI:58909 4-deoxy-4-formamido-alpha-L-arabinopyranosyl ditrans,polycis-undecaprenyl phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58909 CHEBI:58908 L-galactose 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58908 CHEBI:58907 precursor Z(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58907 CHEBI:58906 sphingosine-1-phosphocholine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58906 CHEBI:58905 S-sulfanylglutathionate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58905 CHEBI:83925 non-proteinogenic alpha-amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83925 CHEBI:58903 Delta(11)-fatty acyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58903 CHEBI:58902 beta-L-aspartylhydroxamic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58902 UBERON:0015128 subepicardial layer of epicardium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015128 subepicardial connective tissue|perimysial connective tissue of subepicardium CHEBI:83922 (R)-fenbuconazole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83922 CHEBI:83921 (S)-fenbuconazole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83921 UBERON:0015129 epicardial fat biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015129 epicardial adipose tissue|pericardial adipose tissue Visceral intrapericardial fat contiguous with the myocardial surface. CHEBI:83920 4-(4-chlorophenyl)-2-phenyl-2-(1,2,4-triazol-1-ylmethyl)butanenitrile biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83920 CHEBI:58901 2-(E)-O-feruloyl-D-galactarate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58901 CHEBI:58900 UDP-2-acetamido-2-deoxy-D-glucuronate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58900 CHEBI:19333 2,4,6-trichloroanisole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_19333 CHEBI:19331 (2,4,5-trichlorophenoxy)acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_19331 GO:0102030 dTDP-L-rhamnose synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102030 MetaCyc:DTDPRHAMSYNTHMULTI-RXN Catalysis of the reaction: dTDP-6-deoxy-beta-L-mannose + NAD+ <=> dTDP-4-dehydro-6-deoxy-alpha-D-glucose + NADH + H+. CHEBI:83939 1-acyl-2-stearoyl-sn-glycero-3-phospho-(1D-myo-inositol)(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83939 CHEBI:83938 14-hydroxypalmitate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83938 CHEBI:83937 14-hydroxypalmitic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83937 GO:0102031 4-acetamido-4,6-dideoxy-D-galactose transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102031 RHEA:28759|EC:2.4.1.325|MetaCyc:FUC4NACTRANS-RXN Catalysis of the reaction: dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose + beta-D-ManNAcA-(1->4)-alpha-D-GlcNAc-1-diphospho-ditrans,polycis-undecaprenol <=> H+ + alpha-D-FucNAc4-(1->4)-beta-D-ManNAcA-(1->4)-D-GlcNAc-undecaprenyl diphosphate + dTDP. CHEBI:83936 15-hydroxypalmitate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83936 CHEBI:83935 15-hydroxypalmitic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83935 GO:0102033 long-chain fatty acid omega-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102033 RHEA:56748|MetaCyc:RXN-16394|EC:1.14.14.80 cytochrome P450 fatty acid omega-hydroxylase activity Catalysis of the reaction: an omega-methyl-long-chain fatty acid + O2 + reduced [NADPH--hemoprotein reductase] = an omega-hydroxy-long-chain fatty acid + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]. GO:0102036 methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102036 MetaCyc:METHCOCLTH-RXN|RHEA:45200|EC:2.1.1.258 Catalysis of the reaction: a tetrahydrofolate + a [methyl-Co(III) corrinoid Fe-S protein] <=> an N5-methyl-tetrahydrofolate + a [Co(I) corrinoid Fe-S protein]. CHEBI:10956 (E)-cinnamoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_10956 GO:0102035 isobutyryl-CoA:FAD oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102035 MetaCyc:MEPROPCOA-FAD-RXN|EC:1.3.8.5 Catalysis of the reaction: H+ + isobutyryl-CoA + FAD <=> methacrylyl-CoA + FADH2. GO:0102038 4-nitrobenzyl alcohol oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102038 MetaCyc:R362-RXN Catalysis of the reaction: 4-nitrobenzyl alcohol + O2 <=> 4-nitrobenzaldehyde + hydrogen peroxide. GO:0102037 4-nitrotoluene monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102037 MetaCyc:R361-RXN Catalysis of the reaction: H+ + 4-nitrotoluene + NADH + O2 <=> 4-nitrobenzyl alcohol + NAD+ + H2O. GO:0102039 alkylhydroperoxide reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102039 EC:1.11.1.26|MetaCyc:R4-RXN Catalysis of the reaction: H2O + NAD + an alcohol <=> NADH + H+ + an organic hydroperoxide. GO:0102041 7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102041 RHEA:35951|EC:2.5.1.105|MetaCyc:RXN-10009 Catalysis of the reaction: 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate = N-[(7,8-dihydropterin-6-yl)methyl]-4-(beta-D-ribofuranosyl)aniline 5'-phosphate + diphosphoric acid. GO:0102040 fumarate reductase (menaquinone) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102040 RHEA:27834|EC:1.3.5.4|MetaCyc:R601-RXN Catalysis of the reaction: fumarate + a menaquinol = succinate + a menaquinone. GO:0102043 isopentenyl phosphate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102043 RHEA:33963|EC:2.7.4.26|MetaCyc:RXN-10068 Catalysis of the reaction: isopentenyl phosphate(2-) + ATP(4-) <=> isopentenyl diphosphate(3-) + ADP(3-). GO:0102042 dehydroquinate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102042 MetaCyc:RXN-10032|EC:1.4.1.24|RHEA:25956 Catalysis of the reaction: 2-amino-2,3,7-trideoxy-D-lyxo-hept-6-ulosonic acid + H2O + NAD = 3-dehydroquinate + ammonium + NADH + H+. UBERON:0015181 neck of tooth biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015181 cervix dentis|cervical zone of tooth|cervical margin of tooth|tooth neck|dental neck|cervix of tooth|collumn dentis The slightly constricted part of a tooth, between the crown and the root. GO:0102045 3-chlorobenzoate-3,4-oxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102045 MetaCyc:RXN-10422 Catalysis of the reaction: 3-chlorobenzoate + O2 + a reduced electron acceptor <=> 3-chlorobenzoate-cis-3,4-diol + an oxidized electron acceptor. GO:0102044 3-chlorobenzoate-4,5-oxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102044 MetaCyc:RXN-10421 Catalysis of the reaction: 3-chlorobenzoate + O2 + a reduced electron acceptor <=> 3-chlorobenzoate-cis-4,5-diol + an oxidized electron acceptor. CHEBI:83946 N-acyl-L-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83946 GO:0102047 indole-3-acetyl-glycine synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102047 MetaCyc:RXN-10429 Catalysis of the reaction: indole-3-acetate + glycine + ATP(4-) <=> H+ + indole-3-acetyl-glycine + AMP(2-) + diphosphoric acid. CHEBI:83944 D-alanine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83944 GO:0102046 3,4-dichlorobenzoate-4,5-oxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102046 MetaCyc:RXN-10427 Catalysis of the reaction: 3,4-dichlorobenzoate + O2 + a reduced electron acceptor <=> 3,4-dichlorobenzoate-cis-4,5-diol + an oxidized electron acceptor. CHEBI:83943 L-alanine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83943 GO:0102049 indole-3-acetyl-methionine synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102049 MetaCyc:RXN-10431 Catalysis of the reaction: indole-3-acetate + L-methionine + ATP(4-) <=> H+ + indole-3-acetyl-methionine + AMP(2-) + diphosphoric acid. CHEBI:83942 N(6)-(UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-gamma-glutamyl)-D-lysine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83942 GO:0102048 indole-3-acetyl-isoleucine synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102048 MetaCyc:RXN-10430 Catalysis of the reaction: indole-3-acetate + L-isoleucine + ATP(4-) <=> H+ + indole-3-acetyl-isoleucine + AMP(2-) + diphosphoric acid. CHEBI:83941 N-acetyl-D-muramoyl-L-alaninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83941 CHEBI:83940 1-stearoyl-2-acyl-sn-glycero-3-phospho-(1D-myo-inositol)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83940 CHEBI:34939 prostaglandin D3 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_34939 PO:0005679 epidermis biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0005679 portion of epidermal tissue (exact)|表皮 (Japanese, exact)|epidermides (exact, plural)|multiseriate epidermis (related)|dermal tissue (exact)|epidermises (exact, plural)|epidermal layer (exact)|epidermis (Spanish, exact) A portion of plant tissue (PO:0009007) composed of epidermal cells (PO:0004013) that develops from the protoderm (PO:0006210) and covers the surface of a plant structure (PO:0009011). GO:0102050 indole-3-acetyl-tyrosine synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102050 MetaCyc:RXN-10432 Catalysis of the reaction: indole-3-acetate + L-tyrosine + ATP(4-) <=> H+ + indole-3-acetyl-tyrosine + AMP(2-) + diphosphoric acid. GO:0102052 indole-3-acetyl-proline synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102052 MetaCyc:RXN-10434 Catalysis of the reaction: indole-3-acetate + L-proline + ATP(4-) <=> H+ + indole-3-acetyl-proline + AMP(2-) + diphosphoric acid. GO:0102051 indole-3-acetyl-tryptophan synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102051 MetaCyc:RXN-10433 Catalysis of the reaction: indole-3-acetate + L-tryptophan + ATP(4-) <=> H+ + indole-3-acetyl-tryptophan + AMP(2-) + diphosphoric acid. GO:0102054 maleylpyruvate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102054 RHEA:47956|MetaCyc:RXN-10447 Catalysis of the reaction: 3-maleylpyruvate(2-) + H2O <=> H+ + maleate(2-) + pyruvate. GO:0102053 (-)-jasmonoyl-isoleucine synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102053 MetaCyc:RXN-10435 Catalysis of the reaction: (-)-jasmonate + L-isoleucine + ATP(4-) <=> H+ + (-)-jasmonoyl-L-isoleucine + AMP(2-) + diphosphoric acid. GO:0102056 11-hydroxyjasmonate sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102056 MetaCyc:RXN-10453|RHEA:52732|EC:2.8.2.39 Catalysis of the reaction: 3'-phosphonato-5'-adenylyl sulfate + an 11-hydroxyjasmonate <=> adenosine 3',5'-bismonophosphate + H+ + an 11-hydroxyjasmonate sulfate. CHEBI:83958 (2E,6E,10E)-omega-hydroxyfarnesyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83958 CHEBI:83957 1-O-(1,2-saturated-alkyl)-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83957 UBERON:0015172 endometrial blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015172 blood vessel of endometrium A blood vessel that is part of a endometrium. GO:0102055 12-hydroxyjasmonate sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102055 MetaCyc:RXN-10451|RHEA:52728|EC:2.8.2.39 Catalysis of the reaction: 3'-phosphonato-5'-adenylyl sulfate + a 12-hydroxyjasmonate <=> adenosine 3',5'-bismonophosphate + a 12-hydroxyjasmonate sulfate. GO:0102058 jasmonoyl-leucine synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102058 MetaCyc:RXN-10459 Catalysis of the reaction: L-leucine + ATP(4-) + a jasmonic acid <=> AMP(2-) + diphosphoric acid + a jasmonoyl-leucine. CHEBI:83955 2-saturated fatty acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83955 GO:0102057 jasmonoyl-valine synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102057 MetaCyc:RXN-10457 Catalysis of the reaction: L-valine + ATP(4-) + a jasmonic acid <=> AMP(2-) + diphosphoric acid + a jasmonoyl-valine. CHEBI:83953 omega-hydroxygeranylgeraniol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83953 GO:0102059 2-cis,6-cis-farnesyl pyrophosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102059 MetaCyc:RXN-10481|RHEA:27810|EC:2.5.1.92 Catalysis of the reaction: prenyl diphosphate + 2 isopentenyl diphosphate <=> 2 diphosphoric acid + 2-cis,6-cis-farnesyl diphosphate. CHEBI:83952 (2E,6E,10E)-geranylgeranate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83952 UBERON:0015179 somite boundary epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015179 intersomitic epithelium|intersomitic membrane Epithelium located in the intersomitic region. CHEBI:34905 paraquat biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_34905 UBERON:0015178 somite border biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015178 intersomitic junction|intersomitic boundary|segmental border|inter-somited border|somite boundary|intersomitic fissure A region of somite adjacent to presomitic mesoderm. CHEBI:83951 (2E,6E,10E)-omega-hydroxyfarnesol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83951 CHEBI:10979 (R)-3-[(R)-3-hydroxybutanoyloxy]butanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_10979 CHEBI:10970 (R)-2-benzylsuccinyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_10970 GO:0102061 endo-beta-bergamontene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102061 MetaCyc:RXN-10483|RHEA:30467|EC:4.2.3.53 Catalysis of the reaction: 2-cis,6-cis-farnesyl diphosphate <=> (+)-endo-beta-bergamotene + diphosphoric acid. GO:0102060 endo-alpha-bergamontene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102060 RHEA:30471|MetaCyc:RXN-10482|EC:4.2.3.54 Catalysis of the reaction: 2-cis,6-cis-farnesyl diphosphate <=> (-)-endo-alpha-bergamotene + diphosphoric acid. GO:0102063 beta-curcumene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102063 MetaCyc:RXN-10598 Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> diphosphoric acid + (-)-beta-curcumene. GO:0102062 alpha-santalene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102062 EC:4.2.3.50|MetaCyc:RXN-10567|RHEA:30463 Catalysis of the reaction: 2-cis,6-cis-farnesyl diphosphate <=> (+)-alpha-santalene + diphosphoric acid. UBERON:0015165 multi-unit eye biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015165 An eye consisting of multiple light-sensing organs GO:0102065 patchoulene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102065 MetaCyc:RXN-10602 Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> diphosphoric acid + gamma-patchoulene. GO:0102064 gamma-curcumene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102064 EC:4.2.3.94|RHEA:32031|MetaCyc:RXN-10599 Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> gamma-curcumene + diphosphoric acid. GO:0102067 geranylgeranyl diphosphate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102067 RHEA:26229|EC:1.3.1.83|MetaCyc:RXN-10625 Catalysis of the reaction: (E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate + 3 NADP <=> 2-trans,6-trans,10-trans-geranylgeranyl diphosphate + 3 NADPH + 3 H+. CHEBI:83969 3-methylpalmitoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83969 UBERON:0015161 inferior branch of oculomotor nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015161 ventral ramus of occulomotor nerve|ventral ramus of oculomotor nerve|ramus inferior nervi oculomotorii|ramus inferior (nervus oculomotorius [III])|inferior ramus of oculomotor nerve|ramus inferior nervus oculomotorii|inferior division of oculomotor nerve|oculomotor nerve inferior division The inferior branch of the oculomotor nerve or the inferior division, the larger, divides into three branches. One passes beneath the optic nerve to the medial rectus. Another, to the inferior rectus. The third and longest runs forward between the inferior recti and lateralis to the inferior oblique. From the last a short thick branch is given off to the lower part of the ciliary ganglion, and forms its short root. All these branches enter the muscles on their ocular surfaces, with the exception of the nerve to the inferior oblique, which enters the muscle at its posterior border. GO:0102066 alpha-patchoulene synthase activityy biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102066 MetaCyc:RXN-10603 Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphoric acid + alpha-patchoulene. CHEBI:83968 3-methyl fatty acyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83968 GO:0102069 zerumbone synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102069 MetaCyc:RXN-10629|EC:1.1.1.326|RHEA:32327 Catalysis of the reaction: 8-hydroxy-alpha-humulene + NAD <=> zerumbone + NADH + H+. GO:0102068 alpha-humulene 10-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102068 MetaCyc:RXN-10628|RHEA:32491|EC:1.14.14.113 Catalysis of the reaction: (1E,4E,8E)-alpha-humulene + NADPH + O2 + H+ <=> 10-hydroxy-alpha-humulene + NADP + H2O. CHEBI:34911 permethrin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_34911 CHEBI:83966 D-arginine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83966 CHEBI:83965 L-arginine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83965 CHEBI:10965 (R)-2,3,4,5-tetrahydrodipicolinate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_10965 CHEBI:83963 2-acetamido-2-deoxy-3-O-(4-deoxy-alpha-L-threo-hex-4-enopyranosyluronate)-4-O-sulfonato-D-galactopyranose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83963 CHEBI:83960 N(omega)-alpha-(ADP-D-ribosyl)-L-arginine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83960 GO:0102070 18-hydroxyoleate peroxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102070 MetaCyc:RXN-1064 Catalysis of the reaction: 18-hydroxyoleate + a lipid hydroperoxide <=> 9,10-epoxy-18-hydroxystearate + a lipid alcohol. GO:0043050 pharyngeal pumping biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043050 pumping behavior The contraction and relaxation movements of the pharyngeal muscle that mediate feeding in nematodes. GO:0008729 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008729 GO:0008728 GTP diphosphokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008728 RHEA:22088|MetaCyc:GTPPYPHOSKIN-RXN|EC:2.7.6.5 GPSII|guanosine 3',5'-polyphosphate synthase activity|ppGpp synthetase I activity|GPSI|ATP:GTP 3'-diphosphotransferase activity|(p)ppGpp synthetase II|guanosine pentaphosphate synthetase activity|guanosine 5',3'-polyphosphate synthetase activity|stringent factor activity|GTP pyrophosphokinase activity|ATP-GTP 3'-diphosphotransferase activity|(p)ppGpp synthetase I Catalysis of the reaction: ATP + GTP = AMP + guanosine 3'-diphosphate 5'-triphosphate. GO:0008727 GDP-mannose mannosyl hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008727 RHEA:28102|MetaCyc:GDPMANMANHYDRO-RXN Catalysis of the reaction: GDP-alpha-D-mannose + H2O = GDP + D-mannose + H+. GO:0043052 thermotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043052 Wikipedia:Thermotaxis taxis in response to temperature stimulus The directed movement of a motile cell or organism in response to a temperature gradient. Movement may be towards either a higher or lower temperature. GO:0008726 alkanesulfonate monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008726 RHEA:23064|EC:1.14.14.5|MetaCyc:RXN0-280 FMNH(2)-dependent aliphatic sulfonate monooxygenase activity|alkanesulfonate, reduced-FMN:oxygen oxidoreductase activity|SsuD|alkanesulphonate monooxygenase activity|FMNH2-dependent aliphatic sulfonate monooxygenase activity|FMNH(2)-dependent alkanesulfonate monooxygenase activity|sulfate starvation-induced protein 6 activity Catalysis of the reaction: an alkanesulfonate + O2 + FMNH2 = an aldehyde + sulfite + H2O + FMN. GO:0043051 regulation of pharyngeal pumping biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043051 Any process that modulates the contraction and relaxation movements of the pharyngeal muscle that mediates feeding in nematodes. GO:0008725 DNA-3-methyladenine glycosylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008725 MetaCyc:3.2.2.21-RXN|MetaCyc:3.2.2.20-RXN|EC:3.2.2.21|EC:3.2.2.20 3-methyladenine DNA glycosylase I|alkylated-DNA glycohydrolase (releasing methyladenine and methylguanine)|DNA-3-methyladenine glycosidase I activity|deoxyribonucleate 3-methyladenine glycosidase I|DNA-3-methyladenine glycosylase I activity|DNA glycosidase I activity Catalysis of the reaction: DNA containing 3-methyladenine + H2O = DNA with abasic site + 3-methyladenine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methyladenine and the deoxyribose sugar to remove the 3-methyladenine, leaving an abasic site. GO:0008724 obsolete DNA topoisomerase IV activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008724 DNA topoisomerase IV activity OBSOLETE. Catalysis of the ATP-independent breakage of DNA, followed by passage and rejoining. It also catalyzes the relaxation of supercoiled DNA, and the decatenation and unknotting of DNA in vivo. GO:0008723 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008723 UBERON:0005749 glomerular tuft biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005749 glomerular capillary tuft|glomerulus The capillary loops of the kidney that normally function as a filtration unit[MP]. GO:0008722 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008722 GO:0008721 D-serine ammonia-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008721 Reactome:R-HSA-9034539|Reactome:R-HSA-9014741|MetaCyc:DSERDEAM-RXN|EC:4.3.1.18|RHEA:13977 D-serine ammonia-lyase (pyruvate-forming)|D-serine hydro-lyase (deaminating) activity|D-serine dehydratase activity|D-serine deaminase activity|D-hydroxyaminoacid dehydratase activity|D-serine dehydration activity|D-serine dehydrase activity|D-serine dehydratase (deaminating) activity|D-hydroxy amino acid dehydratase activity|D-serine hydrolase activity Catalysis of the reaction: D-serine = pyruvate + NH3. GO:0043058 regulation of backward locomotion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043058 Any process that modulates the speed, mechanical force, or rhythm of the posterior movement of an organism. GO:0008720 D-lactate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008720 MetaCyc:DLACTDEHYDROGNAD-RXN|EC:1.1.1.28|KEGG_REACTION:R00704|RHEA:16369 D-lactic acid dehydrogenase activity|D-lactic dehydrogenase activity Catalysis of the reaction: (R)-lactate + NAD(+) = H(+) + NADH + pyruvate. GO:0043057 backward locomotion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043057 Posterior movement of an organism, e.g. following the direction of the tail of an animal. GO:0043059 regulation of forward locomotion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043059 Any process that modulates the speed, mechanical force, or rhythm of the anterior movement of an organism. GO:0043054 dauer exit biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043054 exit from nematode dormancy Exit from the facultative diapause of the dauer (enduring) larval stage of nematode development. GO:0043053 dauer entry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043053 nematode entry into dormancy Entry into the facultative diapause of the dauer (enduring) larval stage of nematode development. GO:0043056 forward locomotion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043056 Anterior movement of an organism, following the direction of the head of the animal. GO:0043055 maintenance of dauer biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043055 maintenance of dormancy in the nematode Maintenance of a nematode during the facultative diapause of the dauer (enduring) larval stage of nematode development. UBERON:0005754 rostral part of nephrogenic cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005754 The initial renal anlage that develops from the most rostral part of the nephrogenic cord is termed the pronephros. UBERON:0005753 caudal part of nephrogenic cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005753 rear portion of nephrogenic cord|caudal portion of nephrogenic cord|caudal region of nephrogenic cord|rear part of nephrogenic cord The metanephros develops from the most caudal part of the nephrogenic cord that is itself derived from the intermediate plate mesoderm. GO:0043061 meiotic metaphase II plate congression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043061 The alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the meiotic spindle, during meiosis II. GO:0008739 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008739 GO:0043060 meiotic metaphase I plate congression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043060 The alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the meiotic spindle, during meiosis I. GO:0008738 L-fuculose-phosphate aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008738 EC:4.1.2.17|RHEA:12933|KEGG_REACTION:R02262|MetaCyc:FUCPALDOL-RXN L-fuculose-1-phosphate lactaldehyde-lyase activity|L-fuculose-1-phosphate S-lactaldehyde-lyase (glycerone-phosphate-forming)|L-fuculose 1-phosphate aldolase activity|fuculose aldolase activity Catalysis of the reaction: L-fuculose 1-phosphate = (S)-lactaldehyde + glycerone phosphate. GO:0043063 intercellular bridge organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043063 intercellular bridge organization and biogenesis|intercellular bridge organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the intracellular bridge. An intracellular bridge is a direct link between the cytoplasms of sister cells that allows cells to communicate with one another. GO:0008737 L-fuculokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008737 MetaCyc:FUCULOKIN-RXN|RHEA:12376|EC:2.7.1.51|KEGG_REACTION:R03241 L-fuculose kinase activity|ATP:L-fuculose 1-phosphotransferase activity|L-fuculokinase (phosphorylating) Catalysis of the reaction: L-fuculose + ATP = L-fuculose 1-phosphate + ADP + 2 H(+). GO:0043062 extracellular structure organization biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0043062 extracellular structure organisation|extracellular structure organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite. GO:0008736 L-fucose isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008736 EC:5.3.1.25|MetaCyc:FUCISOM-RXN|RHEA:17233 L-fucose ketol-isomerase activity|L-fucose aldose-ketose-isomerase activity Catalysis of the reaction: L-fucose = L-fuculose. GO:0008735 carnitine dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008735 KEGG_REACTION:R01925|EC:4.2.1.89|MetaCyc:CARNDEHYDRA-RXN|RHEA:14577 L-carnitine dehydratase activity|L-carnitine hydro-lyase activity|L-carnitine hydro-lyase [4-(trimethylammonio)but-2-enoate-forming] Catalysis of the reaction: (R)-carnitine = crotono-betaine + H(2)O. GO:0008734 L-aspartate oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008734 EC:1.4.3.16|MetaCyc:L-ASPARTATE-OXID-RXN|MetaCyc:RXN-9772|RHEA:25876 L-aspartate:oxygen oxidoreductase Catalysis of the reaction: L-aspartate + O2 = iminosuccinate + hydrogen peroxide. GO:0008733 L-arabinose isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008733 RHEA:14821|KEGG_REACTION:R01761|MetaCyc:ARABISOM-RXN|EC:5.3.1.4 L-arabinose aldose-ketose-isomerase activity|L-arabinose ketol-isomerase activity Catalysis of the reaction: L-arabinose = L-ribulose. GO:0008732 L-allo-threonine aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008732 RHEA:26209|EC:4.1.2.-|MetaCyc:LTAA-RXN L-allo-threonine acetaldehyde-lyase activity|LtaA Catalysis of the reaction: L-allo-threonine = glycine + acetaldehyde. GO:0043069 negative regulation of programmed cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043069 down-regulation of programmed cell death|inhibition of programmed cell death|down regulation of programmed cell death|negative regulation of non-apoptotic programmed cell death|downregulation of programmed cell death Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. GO:0043068 positive regulation of programmed cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043068 activation of programmed cell death|stimulation of programmed cell death|up-regulation of programmed cell death|upregulation of programmed cell death|positive regulation of non-apoptotic programmed cell death|up regulation of programmed cell death Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. GO:0008731 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008731 GO:0008730 L(+)-tartrate dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008730 EC:4.2.1.32|RHEA:15413|MetaCyc:LTARTDEHYDRA-RXN|KEGG_REACTION:R00339 L-(+)-tartaric acid dehydratase activity|(R,R)-tartrate hydro-lyase activity|tartrate dehydratase activity|L-tartrate dehydratase activity|(R,R)-tartrate hydro-lyase (oxaloacetate-forming)|tartaric acid dehydrase activity Catalysis of the reaction: L-tartrate = H(2)O + oxaloacetate. GO:0043065 positive regulation of apoptotic process biolink:BiologicalProcess go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0043065 pro-apoptosis|up-regulation of apoptosis|upregulation of apoptosis|positive regulation of apoptosis|up regulation of apoptosis|activation of apoptosis|stimulation of apoptosis Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process. GO:0043064 obsolete flagellum organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043064 flagellum organisation|flagellum organization|flagellum organization and biogenesis OBSOLETE. A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a flagellum, a long thin projection from a cell, used in movement. GO:0043067 regulation of programmed cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043067 regulation of non-apoptotic programmed cell death Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. GO:0043066 negative regulation of apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043066 down-regulation of apoptosis|apoptosis inhibitor activity|inhibition of apoptosis|anti-apoptosis|down regulation of apoptosis|downregulation of apoptosis|negative regulation of apoptosis|pro-survival Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process. CHEBI:138518 dialkyl phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138518 NCBITaxon:7147 Diptera organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_7147 flies|flies UBERON:0005745 optic foramen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005745 optic canal|optic nerve (II) foramen|optic nerve foramen|optic foramen|canalis opticus|foramen opticum ossis sphenoidalis An opening in the skull through which cranial nerve II passes.[MP]. UBERON:0005744 bone foramen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005744 foramina@fr|foramens@fr|foramen Anatomical space that is an opening in a bone, usually for passage of blood vessels or nerves. UBERON:0005742 adventitia biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005742 tunica advetitia|tunica externa An outermost connective tissue covering of an organ, vessel, or other structure[WP]. UBERON:0005740 tunica intima of artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005740 tunica interna (intima)(arteriae)|arterial intima A tunica intima that is part of a artery. GO:0008707 4-phytase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008707 MetaCyc:6-PHYT-RXN|EC:3.1.3.26|RHEA:20960 6-phytase activity|phytase activity|6-phytase (name based on 1L-numbering system and not 1D-numbering)|myo-inositol-hexakisphosphate 6-phosphohydrolase activity|phytate 6-phosphatase activity Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = 1-myo-inositol 1,2,3,4,5-pentakisphosphate + phosphate. GO:0043072 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043072 GO:0008706 6-phospho-beta-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008706 RHEA:10772|MetaCyc:6-PHOSPHO-BETA-GLUCOSIDASE-RXN|EC:3.2.1.86 6-phospho-beta-D-glucosyl-(1,4)-D-glucose glucohydrolase activity|phospho-beta-glucosidase activity|phospho-beta-glucosidase A|phosphocellobiase activity Catalysis of the reaction: 6-phospho-beta-D-glucoside-(1,4)-D-glucose + H2O = D-glucose 6-phosphate + glucose. GO:0043071 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043071 GO:0008705 methionine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008705 RHEA:11172|MetaCyc:HOMOCYSMETB12-RXN|Reactome:R-HSA-174374|KEGG_REACTION:R00946|EC:2.1.1.13|Reactome:R-HSA-3149539 vitamin B12 methyltransferase activity|methionine synthase (cobalamin-dependent) activity|N(5)-methyltetrahydrofolate--homocysteine cobalamin methyltransferase activity|5-methyltetrahydrofolate:L-homocysteine S-methyltransferase activity|MetH|methyltetrahydrofolate--homocysteine vitamin B12 methyltransferase activity|tetrahydropteroylglutamic methyltransferase activity|N5-methyltetrahydrofolic-homocysteine vitamin B12 transmethylase activity|5-methyltetrahydrofolate-homocysteine S-methyltransferase activity|5-methyltetrahydrofolate--homocysteine transmethylase activity|5-methyltetrahydrofolate--homocysteine S-methyltransferase activity|B12 N5-methyltetrahydrofolate homocysteine methyltransferase activity|N5-methyltetrahydrofolate-homocysteine cobalamin methyltransferase activity|N-methyltetrahydrofolate:L-homocysteine methyltransferase activity|N(5)-methyltetrahydrofolate methyltransferase activity|tetrahydrofolate methyltransferase activity|B12 N(5)-methyltetrahydrofolate homocysteine methyltransferase activity|cobalamin-dependent methionine synthase activity|tetrahydropteroylglutamate methyltransferase activity|N5-methyltetrahydrofolate methyltransferase activity|N(5)-methyltetrahydrofolic--homocysteine vitamin B12 transmethylase activity Catalysis of the reaction: (6S)-5-methyl-5,6,7,8-tetrahydrofolate + L-homocysteine = (6S)-5,6,7,8-tetrahydrofolate + L-methionine. GO:0043074 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043074 GO:0008704 5-carboxymethyl-2-hydroxymuconate delta-isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008704 EC:5.3.3.10|MetaCyc:5.3.3.10-RXN|UM-BBD_reactionID:r0366|RHEA:18813 hpaG1|2-hydroxyhepta-2,4-diene-1,7-dioate isomerase|5-carboxymethyl-2-hydroxymuconic acid isomerase activity|HHDD isomerase activity|5-carboxymethyl-2-hydroxymuconate delta2,Delta4-2-oxo,Delta3-isomerase activity|5-carboxymethyl-2-hydroxymuconate D-isomerase activity|hpaG-1|CHM isomerase activity Catalysis of the reaction: 5-carboxymethyl-2-hydroxymuconate = 5-carboxy-2-oxohept-3-enedioate. GO:0043073 germ cell nucleus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043073 germ-cell nucleus The nucleus of a germ cell, a reproductive cell in multicellular organisms. GO:0008703 5-amino-6-(5-phosphoribosylamino)uracil reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008703 MetaCyc:RIBOFLAVINSYNREDUC-RXN|EC:1.1.1.193|KEGG_REACTION:R03458|RHEA:17845 5-amino-6-(5-phosphoribitylamino)uracil:NADP+ 1'-oxidoreductase activity|aminodioxyphosphoribosylaminopyrimidine reductase activity|5-amino-6-(5'-phosphoribosylamino)uracil reductase activity Catalysis of the reaction: 5-amino-6-(5-phosphoribitylamino)uracil + NADP(+) = 5-amino-6-(5-phosphoribosylamino)uracil + H(+) + NADPH. UBERON:0005729 pectoral appendage field biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005729 pectoral appendage field of lateral plate mesoderm|pectoral fin field A limb/fin field that has the potential to develop into a pectoral appendage bud mesenchyme. GO:0008702 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008702 UBERON:0005728 extraembryonic mesoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005728 extraembryonic mesenchyme|extra-embryonic mesoderm . GO:0008701 4-hydroxy-2-oxovalerate aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008701 UM-BBD_enzymeID:e0077|EC:4.1.3.39|RHEA:22624|KEGG_REACTION:R00750|MetaCyc:MHPELY-RXN 4-hydroxy-2-oxopentanoate pyruvate-lyase activity|4-hydroxy-2-oxopentanoate pyruvate-lyase (acetaldehyde-forming) activity|4-hydroxy-2-oxovalerate pyruvate-lyase activity|DmpG|4-hydroxy-2-ketovalerate aldolase activity|HOA Catalysis of the reaction: 4-hydroxy-2-oxopentanoate = acetaldehyde + pyruvate. GO:0043070 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043070 GO:0008700 4-hydroxy-2-oxoglutarate aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008700 RHEA:18169|Reactome:R-HSA-6784423|EC:4.1.3.16|MetaCyc:4OH2OXOGLUTARALDOL-RXN KHG-aldolase activity|4-hydroxy-2-ketoglutarate aldolase activity|hydroxyketoglutarate aldolase activity|hydroxyketoglutaric aldolase activity|4-hydroxy-2-ketoglutaric aldolase activity|DL-4-hydroxy-2-ketoglutarate aldolase activity|2-keto-4-hydroxybutyrate aldolase activity|2-keto-4-hydroxyglutaric aldolase activity|4-hydroxy-2-oxoglutarate glyoxylate-lyase activity|2-oxo-4-hydroxyglutarate aldolase activity|2-oxo-4-hydroxyglutaric aldolase activity|2-keto-4-hydroxyglutarate aldolase activity|4-hydroxy-2-oxoglutarate glyoxylate-lyase (pyruvate-forming) Catalysis of the reaction: 4-hydroxy-2-oxoglutarate = pyruvate + glyoxylate. UBERON:0005726 chemosensory system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005726 GO:0043079 antipodal cell nucleus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043079 The nucleus of an antipodal cell, one of three cells of the embryo sac in angiosperms, found at the chalazal end of the embryo away from the point of entry of the pollen tube, and its descendents. GO:0043076 megasporocyte nucleus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043076 megaspore mother cell nucleus The nucleus of a megasporocyte, a diploid cell that undergoes meiosis to produce four megaspores, and its descendents. GO:0043075 obsolete sperm cell nucleus (sensu Magnoliophyta) biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043075 sperm cell nucleus (sensu Magnoliophyta)|pollen germ-cell nucleus|pollen germ cell nucleus OBSOLETE. The nucleus of a plant pollen cell, the male gamete, and its descendents. GO:0043078 polar nucleus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043078 Either of two nuclei located centrally in a flowering plant embryo sac that eventually fuse to form the endosperm nucleus. GO:0043077 initiation of acetate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043077 initiation of acetate degradation|initiation of acetate breakdown|initiation of acetate catabolism The activation of the chemical reactions and pathways resulting in the breakdown of acetate. CHEBI:2311 Oplophorus luciferin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_2311 UBERON:0005734 tunica adventitia of blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005734 tunica externa vasorum|external coat|tunica adventitia|tunica adventitia of vessel|tunica adventitia vasorum|adventitia externa The outermost layer of a blood vessel, composed mainly of fibrous tissue. UBERON:0005733 limb field biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005733 limb field of lateral plate mesoderm A ring of cells capable of forming a limb. UBERON:0005732 paired limb/fin field biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005732 limb/fin field of lateral plate mesoderm|paired limb/fin field A ring of cells capable of forming a limb or paired fin[Gilbert,modified]. UBERON:0005731 fin field biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005731 fin field of lateral plate mesoderm A limb/fin field that has_potential_to_developmentally_contribute_to a paired fin bud. GO:0008709 cholate 7-alpha-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008709 KEGG_REACTION:R02792|EC:1.1.1.159|MetaCyc:7-ALPHA-HYDROXYSTEROID-DEH-RXN|RHEA:19409 7alpha-hydroxysteroid:NAD+ 7-oxidoreductase activity|7alpha-HSDH|7alpha-hydroxy steroid dehydrogenase activity|7-alpha-hydroxysteroid dehydrogenase activity|7alpha-hydroxysteroid dehydrogenase activity Catalysis of the reaction: cholate + NAD(+) = 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate + H(+) + NADH. UBERON:0005730 pelvic appendage field biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005730 pelvic appendage field of lateral plate mesoderm|pelvic fin field A limb/fin field that has the potential to develop into a pelvic appendage bud mesenchyme. GO:0008708 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008708 GO:0043083 synaptic cleft biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0043083 NIF_Subcellular:sao243541954 The narrow gap that separates the presynaptic and postsynaptic membranes, into which neurotransmitter is released. GO:0008718 D-amino-acid dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008718 RHEA:18125|MetaCyc:DAADEHYDROG-RXN D-amino-acid:acceptor oxidoreductase (deaminating)|D-amino-acid:(acceptor) oxidoreductase (deaminating) Catalysis of the reaction: a D-amino acid + H2O + acceptor = a 2-oxo acid + NH3 + reduced acceptor. GO:0008717 obsolete D-alanyl-D-alanine endopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008717 penicillin-binding protein 8|penicillin-binding protein 7|D-alanyl-D-alanine endopeptidase activity OBSOLETE. (Was not defined before being made obsolete). GO:0043082 megagametophyte egg cell nucleus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043082 The nucleus of a plant egg cell. This nucleus is found at the micropylar end of the embryo. GO:0043085 positive regulation of catalytic activity biolink:BiologicalProcess go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0043085 up-regulation of metalloenzyme activity|stimulation of metalloenzyme activity|up-regulation of enzyme activity|activation of metalloenzyme activity|positive regulation of metalloenzyme activity|up regulation of metalloenzyme activity|upregulation of enzyme activity|positive regulation of enzyme activity|upregulation of metalloenzyme activity|up regulation of enzyme activity|activation of enzyme activity|stimulation of enzyme activity Any process that activates or increases the activity of an enzyme. GO:0008716 D-alanine-D-alanine ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008716 MetaCyc:DALADALALIG-RXN|RHEA:11224|EC:6.3.2.4|KEGG_REACTION:R01150 D-Ala-D-Ala synthetase activity|D-alanyl-D-alanine synthetase activity|alanine:alanine ligase (ADP-forming) activity|alanylalanine synthetase activity|D-alanylalanine synthetase activity|D-alanine:D-alanine ligase (ADP-forming) Catalysis of the reaction: 2 D-alanine + ATP = D-alanyl-D-alanine + ADP + 2 H(+) + phosphate. GO:0043084 penile erection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043084 Wikipedia:Erection#Penile_erection The hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow. GO:0008715 CDP-diacylglycerol diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008715 EC:3.6.1.26|KEGG_REACTION:R01797|MetaCyc:CDPDIGLYPYPHOSPHA-RXN|RHEA:15221 CDP-diacylglycerol phosphatidylhydrolase activity|CDP-diacylglycerol pyrophosphatase activity|cytidine diphosphodiacylglycerol pyrophosphatase activity|CDP diacylglycerol hydrolase activity Catalysis of the reaction: CDP-diacylglycerol + H(2)O = a phosphatidate + CMP + 2 H(+). UBERON:0005719 footplate apical ectodermal ridge biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005719 An apical ectodermal ridge that is part of a footplate. GO:0008714 AMP nucleosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008714 MetaCyc:AMP-NUCLEOSID-RXN|RHEA:20129|KEGG_REACTION:R00182|EC:3.2.2.4 adenylate nucleosidase activity|adenosine monophosphate nucleosidase activity|AMP phosphoribohydrolase activity Catalysis of the reaction: AMP + H(2)O = D-ribose 5-phosphate + adenine. GO:0008713 ADP-heptose-lipopolysaccharide heptosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008713 RHEA:28538|MetaCyc:RXN0-5061 ADP-heptose:LPS heptosyltransferase activity Catalysis of the reaction: heptosyl-KDO2-lipid A + ADP-L-glycero-beta-D-manno-heptose = heptosyl2-KDO2-lipid A + ADP + H+. GO:0008712 ADP-glyceromanno-heptose 6-epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008712 EC:5.1.3.20|RHEA:17577|KEGG_REACTION:R05176|MetaCyc:5.1.3.20-RXN ADPglyceromanno-heptose 6-epimerase activity|ADP-L-glycero-D-manno-heptose 6-epimerase activity Catalysis of the reaction: ADP-D-glycero-D-manno-heptose = ADP-L-glycero-D-manno-heptose. GO:0043081 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043081 GO:0008711 obsolete ADP-L-glycero-D-manno-heptose synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008711 ADP-L-glycero-D-manno-heptose synthase activity OBSOLETE. This term was not defined before being made obsolete. GO:0043080 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043080 GO:0008710 8-amino-7-oxononanoate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008710 EC:2.3.1.47|RHEA:20712|MetaCyc:7KAPSYN-RXN|KEGG_REACTION:R03210 8-amino-7-ketopelargonate synthase activity|AONS activity|7-KAP synthetase activity|6-carboxyhexanoyl-CoA:L-alanine C-carboxyhexanoyltransferase (decarboxylating)|7-keto-8-aminopelargonic synthetase activity|7-keto-8-amino-pelargonic acid synthetase activity|7-keto-8-aminopelargonic acid synthetase activity|8-amino-7-oxopelargonate synthase activity Catalysis of the reaction: L-alanine + H(+) + pimelyl-CoA = 8-amino-7-oxononanoate + CO(2) + CoA. CHEBI:44348 N-ethylsuccinimide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_44348 GO:0043087 regulation of GTPase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043087 regulation of Cdc42 GTPase activity|regulation of Ran GTPase activity|regulation of Ral GTPase activity|regulation of Rho GTPase activity|regulation of ARF GTPase activity|regulation of Rac GTPase activity|regulation of Rab GTPase activity|regulation of Ras GTPase activity|regulation of Rap GTPase activity Any process that modulates the rate of GTP hydrolysis by a GTPase. CHEBI:20391 4-hydroxy-L-lysine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20391 GO:0043086 negative regulation of catalytic activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043086 down-regulation of enzyme activity|inhibition of enzyme activity|negative regulation of metalloenzyme activity|down-regulation of metalloenzyme activity|downregulation of metalloenzyme activity|down regulation of enzyme activity|down regulation of metalloenzyme activity|downregulation of enzyme activity|negative regulation of enzyme activity|inhibition of metalloenzyme activity Any process that stops or reduces the activity of an enzyme. CHEBI:44343 (1R,2S)-1,2-dihydronaphthalene-1,2-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_44343 GO:0043089 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043089 GO:0043088 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043088 CHEBI:20392 4-hydroxyproline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20392 UBERON:0005725 olfactory system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005725 A sensory system that is capable of olfacttion (the sensory perception of smell). UBERON:0005724 roof plate spinal cord region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005724 spinal cord roof|roof plate spinal cord|roofplate spinal cord A tissue that is part of a spinal cord and is part of a roof plate. UBERON:0005723 floor plate spinal cord region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005723 floorplate spinal cord|spinal cord floor|floor plate spinal cord A multi-tissue structure that is part of a spinal cord and is part of a floor plate. UBERON:0005721 pronephric mesoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005721 pronephric bulge|pronephric mesenchyme|pronephric primordium|pronephric anlage A mesoderm that has the potential to develop into a pronephros. UBERON:0005720 hindbrain venous system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005720 rhombencephalon venous system A venous system that is part of a hindbrain. GO:0008719 dihydroneopterin triphosphate 2'-epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008719 MetaCyc:H2NTPEPIM-RXN|RHEA:28346|EC:5.1.99.7 D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase activity Catalysis of the reaction: dihydroneopterin triphosphate = dihydromonapterin-triphosphate. GO:0043094 cellular metabolic compound salvage biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0043094 Any process which produces a useful metabolic compound from derivatives of it without de novo synthesis, as carried out by individual cells. GO:0043093 FtsZ-dependent cytokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043093 Wikipedia:Binary_fission cytokinesis by binary fission|prokaryotic fission|prokaryote-type cytokinesis A cytokinesis process that involves a set of conserved proteins including FtsZ, and results in the formation of two similarly sized and shaped cells. CHEBI:20361 (4-deoxygluc-4-enosyluronic acid)-(1->3)-N-acetyl-D-galactosamine sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20361 GO:0043096 purine nucleobase salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043096 purine base salvage Any process that generates purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from derivatives of them without de novo synthesis. GO:0043095 regulation of GTP cyclohydrolase I activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043095 Any process that modulates the activity of the enzyme GTP cyclohydrolase I. GO:0043090 amino acid import biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043090 amino acid uptake The directed movement of amino acids into a cell or organelle. GO:0043092 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043092 GO:0043091 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043091 CHEBI:44337 N-acetyl-L-glutamate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_44337 GO:0043098 purine deoxyribonucleoside salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043098 Any process which produces a purine deoxyribonucleoside from derivatives of it, without de novo synthesis. GO:0043097 pyrimidine nucleoside salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043097 Any process that generates a pyrimidine nucleoside, one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose, from derivatives of it, without de novo synthesis. GO:0043099 pyrimidine deoxyribonucleoside salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043099 Any process that generates a pyrimidine deoxyribonucleoside from derivatives of it, without de novo synthesis. CHEBI:2376 acarbose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_2376 UBERON:0005792 nephric ridge biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005792 nephric cord Nephric tubules (nephrons) form embryonically along the nephric ridge. The ridge comprises three regions; anterior, middle and posterior. The functional kidney uses nephrons from only one or two regions of the ridge. A pronephric kidney uses only the nephrons from the anterior region of the ridge. A mesonephric kidney uses only the middle region, a metanephric kidney uses only the posterior region and an opisthonephric kidney uses the middle and posterior regions. UBERON:0005795 embryonic uterus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005795 fetal uterus UBERON:0005788 lamina rara interna biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005788 lamina interna of glomerular basement membrane|internal layer of glomerular basement membrane Layer of the glomerular basement membrane adjacent to the glomerular capillary. CHEBI:58961 N-arachidonoylglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58961 CHEBI:19391 2,6-dibromophenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19391 CHEBI:58958 organosulfate oxoanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58958 CHEBI:20346 cinnamyl alcohol beta-D-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20346 CHEBI:44313 N-acetyl-alpha-D-galactosamine 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_44313 CHEBI:44312 beta-muramic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_44312 CHEBI:58956 branched-chain saturated fatty acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58956 CHEBI:58955 branched-chain fatty acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58955 CHEBI:58954 straight-chain saturated fatty acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58954 UBERON:0005777 glomerular basement membrane biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005777 glomerular capillary basement membrane|GBM|glomerular filtration membrane the layer of extracellular matrix that lies between the endothelium of the glomerular capillaries and the podocytes of the inner or visceral layer of the Bowman capsule; it is a fusion of the endothelial cell and podocyte basal laminas and acts as a physical barrier and an ion-selective filter CHEBI:58953 saturated fatty acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58953 CHEBI:58951 short-chain fatty acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58951 CHEBI:58950 very long-chain fatty acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58950 CHEBI:58948 aryl(methyl)malonate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58948 CHEBI:58947 N-acylhomoserinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58947 CHEBI:58946 acyl-CoA oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58946 CHEBI:44303 L-m-tyrosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_44303 CHEBI:2365 (+)-abscisic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_2365 UBERON:0005769 basement membrane of epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005769 basement membrane|membrana basalis|basement membrane of connective tissue An acellular membrane that is part of the epithelium, lies adjacent to the epithelial cells, and is the fusion of the the basal lamina and the reticular lamina. CHEBI:58945 organophosphate oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58945 CHEBI:58944 dialkyl phosphate anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58944 CHEBI:58943 alpha-amino-acid cation residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58943 CHEBI:58942 amino-acid cation residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58942 CHEBI:58941 cyclic tetrapyrrole anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58941 UBERON:0005764 acellular membrane biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005764 A acellular anatomical structure that is the bounding layer of a anatomical structure. CHEBI:19375 2,5-dichloro-cis,cis-muconate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_19375 GO:0018250 peptidyl-dehydroalanine biosynthetic process from peptidyl-tyrosine or peptidyl-serine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018250 RESID:AA0181 peptidyl-dehydroalanine anabolism from peptidyl-tyrosine or peptidyl-serine|peptidyl-dehydroalanine synthesis from peptidyl-tyrosine or peptidyl-serine|peptidyl-dehydroalanine formation from peptidyl-tyrosine or peptidyl-serine The formation of peptidyl-dehydroalanine from either peptidyl-tyrosine by phenyl transfer, or from peptidyl-serine, which is coupled with the formation of 5-imidazolinone by the two neighboring residues, produces an 4-methylidene-imidazole-5-one active site of some amino acid ammonia-lyases; the 4-methylidene-imidazole-5-one, is formed autocatalytically by cyclization and dehydration of the sequence ASG. GO:0033889 N-sulfoglucosamine-3-sulfatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033889 EC:3.1.6.15|MetaCyc:3.1.6.15-RXN chondroitinsulfatase activity|N-sulfo-3-sulfoglucosamine 3-sulfohydrolase activity Catalysis of the hydrolysis of the 3-sulfate groups of the N-sulfo-D-glucosamine 3-O-sulfate units of heparin. GO:0033888 chondro-6-sulfatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033888 KEGG_REACTION:R03518|RHEA:10536|EC:3.1.6.10|MetaCyc:CHONDRO-6-SULFATASE-RXN 4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine-6-sulfate 6-sulfohydrolase activity Catalysis of the reaction: 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine 6-sulfate + H(2)O = 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine + H(+) + sulfate. GO:0033887 chondro-4-sulfatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033887 KEGG_REACTION:R03517|EC:3.1.6.9|RHEA:11444|MetaCyc:CHONDRO-4-SULFATASE-RXN 4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine-4-sulfate 4-sulfohydrolase activity Catalysis of the reaction: 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine 4-sulfate + H(2)O = 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine + H(+) + sulfate. GO:0043212 carbohydrate-exporting ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043212 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carbohydrate(in) -> ADP + phosphate + carbohydrate(out). GO:0043211 ATPase-coupled carbohydrate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043211 carbohydrate ABC transporter|carbohydrate-transporting ATPase activity|ATP-dependent carbohydrate transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of carbohydrates across a membrane. GO:0043214 ABC-type bacteriocin transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043214 ABC-type bacteriocin transmembrane transporter activity|ATPase-coupled bacteriocin transmembrane transporter activity|bacteriocin ABC transporter Enables the transfer of a bacteriocin from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate. GO:0043213 bacteriocin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043213 The directed movement of a bacteriocin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Bacteriocins are a group of antibiotics produced by bacteria and are encoded by a group of naturally occurring plasmids, e.g. Col E1. Bacteriocins are toxic to bacteria closely related to the bacteriocin producing strain. GO:0043210 alkanesulfonate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043210 Interacting selectively and non-covalently with alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group. CHEBI:2179 D-fucopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_2179 GO:0043219 lateral loop biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043219 NIF_Subcellular:sao1354781919|NIF_Subcellular:sao1067215520 paranodal loop|Schwann cell paranodal termination|oligodendrocyte paranodal termination Non-compact myelin located adjacent to the nodes of Ranvier in a myelin segment. These non-compact regions include cytoplasm from the cell responsible for synthesizing the myelin. Lateral loops are found in the paranodal region adjacent to the nodes of Ranvier, while Schmidt-Lantermann clefts are analogous structures found within the compact myelin internode. CHEBI:138589 pneumocysterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138589 GO:0018249 protein dehydration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018249 protein amino acid dehydration The removal of a water group from a protein amino acid. GO:0043216 obsolete ATPase-coupled daunorubicin transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043216 RHEA:33147 ATP-dependent daunorubicin transmembrane transporter activity|daunorubicin ABC transporter|daunorubicin-transporting ATPase activity OBSOLETE. Catalysis of the reaction: ATP + H2O + daunorubicin(in) = ADP + phosphate + daunorubicin(out). GO:0043215 daunorubicin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043215 The directed movement of daunorubicin, an anthracycline antibiotic produced by Streptomyces coeruleorubidus or S. peucetius and used as an antineoplastic into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0018248 obsolete enzyme active site formation via peptidyl cysteine sulfation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018248 enzyme active site formation via S-sulpho-L-cysteine OBSOLETE. The formation of an enzyme active site via transient sulfation of peptidyl-cysteine to form S-sulfo-L-cysteine. GO:0043218 compact myelin biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043218 NIF_Subcellular:sao1123256993 oligodendrocyte compact myelin|Schwann cell compact myelin The portion of the myelin sheath in which layers of cell membrane are tightly juxtaposed, completely excluding cytoplasm. The juxtaposed cytoplasmic surfaces form the major dense line, while the juxtaposed extracellular surfaces form the interperiod line visible in electron micrographs. GO:0043217 myelin maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043217 The process of preserving the structure and function of mature myelin. This includes maintaining the compact structure of myelin necessary for its electrical insulating characteristics as well as the structure of non-compact regions such as Schmidt-Lantermann clefts and paranodal loops. This does not include processes responsible for maintaining the nodes of Ranvier, which are not part of the myelin sheath. GO:0018245 protein O-linked glycosylation via tyrosine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018245 RESID:AA0157 protein amino acid O-linked glycosylation via tyrosine The glycosylation of protein via the O4' atom of peptidyl-tyrosine, O4'-glycosyl-L-tyrosine; the carbohydrate is glucose, the origin for glycogen. GO:0033886 cellulose-polysulfatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033886 MetaCyc:3.1.6.7-RXN|EC:3.1.6.7 cellulose-sulfate sulfohydrolase activity Catalysis of the hydrolysis of the 2- and 3-sulfate groups of the polysulfates of cellulose and charonin. GO:0033885 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033885 EC:3.1.3.76|RHEA:16537|KEGG_REACTION:R07582|MetaCyc:3.1.3.76-RXN sEH|hydroxy fatty acid phosphatase activity|(9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity|(9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate phosphohydrolase activity|soluble epoxide hydrolase activity|dihydroxy fatty acid phosphatase activity|hydroxy lipid phosphatase activity|lipid-phosphate phosphatase activity Catalysis of the reaction: (9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate + H(2)O = (9S,10S)-9,10-dihydroxyoctadecanoate + phosphate. GO:0018244 protein N-linked glycosylation via tryptophan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018244 RESID:AA0156 protein amino acid N-linked glycosylation via tryptophan The glycosylation of protein via peptidyl-tryptophan, 1'-glycosyl-L-tryptophan; results in the formation of an (S)-2-amino-3-(1-D-mannopyranosyloxy-1H-indol-3-yl)propanoic acid residue. CHEBI:138582 19-hydroxyprostaglandin I2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138582 GO:0033884 obsolete phosphoethanolamine/phosphocholine phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033884 phosphoethanolamine phosphohydrolase activity|phosphoethanolamine/phosphocholine phosphatase activity|3X11A|PHOSPHO1 OBSOLETE. Catalysis of the reactions: O-phosphoethanolamine + H2O = ethanolamine + phosphate, and phosphocholine + H2O = choline + phosphate. GO:0018247 protein-phosphoribosyl dephospho-coenzyme A linkage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018247 RESID:AA0167 The linkage of phosphoribosyl dephospho-coenzyme A to protein via peptidyl-serine, to form O-(phosphoribosyl dephospho-coenzyme A)-L-serine; it is uncertain whether the phosphoribosyl glycosidic attachment to the dephospho-coenzyme A is alpha or beta, and through the 2' or the 3' position. GO:0033883 pyridoxal phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033883 RHEA:20533|EC:3.1.3.74|MetaCyc:3.1.3.74-RXN vitamin B6 (pyridoxine) phosphatase activity|PNP phosphatase activity|PLP phosphatase activity|pyridoxal-5'-phosphate phosphohydrolase activity|vitamin B6-phosphate phosphatase activity Catalysis of the reaction: pyridoxal 5'-phosphate + H2O = pyridoxal + phosphate. GO:0018246 protein-coenzyme A linkage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018246 The formation of a linkage between a protein amino acid and coenzyme A. CHEBI:138588 (R)-3-hydroxypentanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138588 GO:0018241 protein O-linked glycosylation via hydroxylysine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018241 RESID:AA0153 protein amino acid O-linked glycosylation via hydroxylysine The glycosylation of protein via the O5 atom of peptidyl-hydroxylysine, forming O5-glycosyl-L-hydroxylysine; the most common form is galactosyl hydroxylysine. GO:0033882 choloyl-CoA hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033882 RHEA:14541|MetaCyc:3.1.2.27-RXN|EC:3.1.2.27 peroxisomal acyl-CoA thioesterase 2 activity|choloyl-coenzyme A thioesterase activity|PTE-2|chenodeoxycholoyl-coenzyme A thioesterase activity Catalysis of the reaction: choloyl-CoA + H2O = cholate + CoA. GO:0033881 bile-acid-CoA hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033881 MetaCyc:BACOAHYDRO-RXN|RHEA:17693|KEGG_REACTION:R07295|EC:3.1.2.26 bile acid-coenzyme A hydrolase activity|deoxycholoyl-CoA hydrolase activity Catalysis of the reaction: deoxycholoyl-CoA + H(2)O = CoA + deoxycholate + H(+). GO:0018240 protein S-linked glycosylation via cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018240 RESID:AA0152 protein amino acid S-linked glycosylation via cysteine The glycosylation of protein via the sulfur atom of peptidyl-cysteine, forming S-glycosyl-L-cysteine. CHEBI:138587 (R)-3-hydroxypentanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138587 GO:0033880 phenylacetyl-CoA hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033880 RHEA:15337|MetaCyc:3.1.2.25-RXN|KEGG_REACTION:R07294|EC:3.1.2.25 phenylglyoxylyl-CoA hydrolase activity Catalysis of the reaction: H(2)O + phenylglyoxylyl-CoA = CoA + H(+) + phenylglyoxylate. GO:0018243 protein O-linked glycosylation via threonine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018243 RESID:AA0155 protein amino acid O-linked glycosylation via threonine The glycosylation of protein via the O3 atom of peptidyl-threonine, forming O3-glycosyl-L-threonine; the most common forms are N-acetylgalactosaminyl, mannosyl, and galactosyl threonine. GO:0018242 protein O-linked glycosylation via serine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018242 RESID:AA0154 protein amino acid O-linked glycosylation via serine The glycosylation of protein via the O3 atom of peptidyl-serine, forming O3-glycosyl-L-serine; the most common forms are N-acetylgalactosaminyl, mannosyl, galactosyl, and xylosyl serine. GO:0018261 peptidyl-lysine guanylylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018261 RESID:AA0228 The guanylylation of peptidyl-lysine to form peptidyl-N6-(phospho-5'-guanosine)-L-lysine. GO:0018260 protein guanylylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018260 protein amino acid guanylylation The addition of phospho-guanosine to a protein amino acid. GO:0033879 acetylajmaline esterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033879 MetaCyc:RXN-8653|MetaCyc:RXN-8652|EC:3.1.1.80 AAE|17-O-acetylajmaline O-acetylhydrolase activity|2beta(R)-17-O-acetylajmalan:acetylesterase activity|acetylajmalan esterase activity Catalysis of the reactions: 17-O-acetylajmaline + H2O = ajmaline + acetate, and 17-O-acetylnorajmaline + H2O = norajmaline + acetate. GO:0033878 hormone-sensitive lipase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033878 MetaCyc:TRIACYLGLYCEROL-LIPASE-RXN|EC:3.1.1.79|MetaCyc:STEROL-ESTERASE-RXN HSL|diacylglycerol acylhydrolase activity Catalysis of the reactions: diacylglycerol + H2O = monoacylglycerol + a carboxylate; triacylglycerol + H2O = diacylglycerol + a carboxylate; and monoacylglycerol + H2O = glycerol + a carboxylate. GO:0033877 succinyl-CoA:(R)-benzylsuccinate CoA-transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033877 MetaCyc:RXN-864|UM-BBD_reactionID:r0329|EC:2.8.3.15|RHEA:16469|KEGG_REACTION:R05588 succinyl-CoA:(R)-2-benzylsuccinate CoA-transferase activity|benzylsuccinate CoA-transferase activity|succinyl-CoA:benzylsuccinate CoA-transferase activity Catalysis of the reaction: (R)-2-benzylsuccinate + succinyl-CoA = (R)-2-benzylsuccinyl-CoA + succinate. GO:0033876 glycochenodeoxycholate sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033876 KEGG_REACTION:R07289|MetaCyc:2.8.2.34-RXN|EC:2.8.2.34|RHEA:17689 3'-phosphoadenylyl-sulfate:glycochenodeoxycholate 7-sulfotransferase activity|BAST|bile acid:PAPS:sulfotransferase activity|bile acid:3'-phosphoadenosine-5'-phosphosulfate sulfotransferase activity Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + glycochenodeoxycholate = adenosine 3',5'-diphosphate + glycochenodeoxycholate 7-sulfate + H(+). GO:0043223 cytoplasmic SCF ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043223 cytoplasmic cullin complex|cytoplasmic Skp1/Cul1/F-box protein complex|cytoplasmic SCF complex A ubiquitin ligase complex, located in the cytoplasm, in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1). GO:0043222 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043222 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043225 Reactome:R-HSA-5690340|Reactome:R-HSA-1454916 anion transmembrane-transporting ATPase activity|anion-transporting ATPase activity|anion ABC transporter|ATPase-coupled anion transmembrane transporter activity|ATP-dependent anion transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + inorganic anion(out) = ADP + phosphate + inorganic anion(in). GO:0043224 nuclear SCF ubiquitin ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043224 nuclear cullin complex|nuclear Skp1/Cul1/F-box protein complex|nuclear SCF complex A ubiquitin ligase complex, located in the nucleus, in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1). GO:0043221 SMC family protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043221 structural maintenance of chromosomes family protein binding Interacting selectively and non-covalently with any protein from the structural maintenance of chromosomes (SMC) family, a group of chromosomal ATPases with a role in mitotic chromosome organization. GO:0043220 Schmidt-Lanterman incisure biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043220 NIF_Subcellular:sao254777664 Schmidt-Lanterman cleft Regions within compact myelin in which the cytoplasmic faces of the enveloping myelin sheath are not tightly juxtaposed, and include cytoplasm from the cell responsible for making the myelin. Schmidt-Lanterman incisures occur in the compact myelin internode, while lateral loops are analogous structures found in the paranodal region adjacent to the nodes of Ranvier. GO:0043227 membrane-bounded organelle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043227 NIF_Subcellular:sao414196390 membrane-enclosed organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. GO:0018259 RNA-protein covalent cross-linking via peptidyl-serine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018259 RESID:AA0213 The formation of a covalent cross-link between RNA and a peptidyl-serine residue by the formation of O-(phospho-5'-5NA)-L-serine. GO:0043226 organelle biolink:CellularComponent go-plus goslim_generic|goslim_chembl|goslim_pir http://purl.obolibrary.org/obo/GO_0043226 NIF_Subcellular:sao1539965131|Wikipedia:Organelle Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane. GO:0043229 intracellular organelle biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0043229 Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. GO:0043228 non-membrane-bounded organelle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043228 NIF_Subcellular:sao1456184038 non-membrane-enclosed organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes. GO:0018256 protein formylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018256 protein amino acid formylation The addition of a formyl group to a protein amino acid. CHEBI:138595 O-phosphocholine-L-serine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138595 GO:0033875 ribonucleoside bisphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033875 ribonucleoside bisphosphate metabolism The chemical reactions and pathways involving a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar. GO:0033874 scymnol sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033874 MetaCyc:2.8.2.32-RXN|KEGG_REACTION:R07798|EC:2.8.2.32|RHEA:15477 Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + 5beta-scymnol = 5beta-scymnol sulfate + adenosine 3',5'-diphosphate + H(+). CHEBI:2181 L-fucopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_2181 GO:0018255 peptide cross-linking via S-glycyl-L-cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018255 RESID:AA0206 The formation of S-(peptidyl-glycyl)-peptidyl-cysteine cross-links by the formation of a thiolester between cysteine and the carboxy-terminal glycine of ubiquitin and other proteins. GO:0033873 petromyzonol sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033873 MetaCyc:2.8.2.31-RXN|RHEA:16997|EC:2.8.2.31|KEGG_REACTION:R07797 PZ-SULT|3'-phosphoadenylyl-sulfate:5alpha-cholan-3alpha,7alpha,12alpha,24-tetrol sulfotransferase activity Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + 5alpha-cholane-3alpha,7alpha,12alpha,24-tetrol = 3alpha,7alpha,12alpha-trihydroxy-5alpha-cholan-24-yl sulfate + adenosine 3',5'-diphosphate + H(+). GO:0018258 protein O-linked glycosylation via hydroxyproline biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018258 RESID:AA0212 protein amino acid O-linked glycosylation via hydroxyproline The glycosylation of proteins via 04 atom of hydroxyproline to form O4-glycosyl-L-hydroxyproline; the most common form is arabinofuranosyl-4-proline. GO:0033872 [heparan sulfate]-glucosamine 3-sulfotransferase 3 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033872 MetaCyc:2.8.2.30-RXN|EC:2.8.2.30 3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine 3-sulfotransferase activity|3-OST-3|heparin-glucosamine 3-sulfotransferase 3 activity|heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A activity|glucosaminyl 3-O-sulfotransferase 3a, 3b activity|heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3 activity|glucosaminyl 3-O-sulfotransferase 3 activity|isoform/isozyme 3a and 3b (3-OST-3A, 3-OST-3B, HS3ST3A, HS3ST3B) Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate. GO:0018257 peptidyl-lysine formylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018257 RESID:AA0211 The modification of peptidyl-lysine to form peptidyl-N6-formyl-L-lysine. GO:0033871 [heparan sulfate]-glucosamine 3-sulfotransferase 2 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033871 MetaCyc:2.8.2.29-RXN|EC:2.8.2.29 heparin-glucosamine 3-sulfotransferase 2 activity|isoform/isozyme 2 (3-OST-2, HS3ST2)|3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine 3-sulfotransferase activity|3-OST-2|heparan sulfate D-glucosaminyl 3-O-sulfotransferase activity|glucosaminyl 3-O-sulfotransferase activity|heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2 activity|glucosaminyl 3-O-sulfotransferase 2 activity Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate; modifies selected glucosamine residues preceded by GlcA2S. GO:0018252 peptide cross-linking via L-seryl-5-imidazolinone glycine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018252 RESID:AA0184 biosynthetic process of protein-protein cross-link via L-seryl-5-imidazolinone glycine|biosynthesis of protein-protein cross-link via L-seryl-5-imidazolinone glycine The formation of the green fluorescent protein chromophore cross-link from the alpha-carboxyl carbon of residue n, a serine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons. CHEBI:138599 4,4'-diapolycopen-4-al biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138599 GO:0033870 thiol sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033870 MetaCyc:THIOL-SULFOTRANSFERASE-RXN|RHEA:14637|EC:2.8.2.16 PAPS sulfotransferase activity|3'-phosphoadenylyl-sulfate:thiol S-sulfotransferase activity|adenosine 3'-phosphate 5'-sulphatophosphate sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenylyl sulfate + a thiol = adenosine 3',5'-bisphosphate + an S-alkyl thiosulfate. GO:0018251 peptidyl-tyrosine dehydrogenation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018251 RESID:AA0183 The oxidation of the C alpha-C beta bond of peptidyl-tyrosine to form peptidyl-dehydrotyrosine coupled with cyclization of neighboring residues. GO:0018254 peptidyl-tyrosine adenylylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018254 RESID:AA0203 peptidyl-tyrosine adenylation The adenylylation of peptidyl-tyrosine to form peptidyl-O4'-(phospho-5'-adenosine)-L-tyrosine. CHEBI:138597 (4R,7R)-7-hydroxy-4-isopropenyl-7-methyloxepan-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138597 GO:0018253 peptide cross-linking via 5-imidazolinone glycine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018253 RESID:AA0188|RESID:AA0187|RESID:AA0184 biosynthesis of protein-protein cross-link via 5-imidazolinone glycine|biosynthetic process of protein-protein cross-link via 5-imidazolinone glycine The formation of a protein active site cross-link from the alpha-carboxyl carbon of residue n, an alanine, serine or cysteine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with an oxidation of residue n+1 to form an active aldehyde. CHEBI:138596 (4S,7S)-7-hydroxy-4-isopropenyl-7-methyloxepan-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138596 GO:0033869 nucleoside bisphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033869 nucleoside bisphosphate catabolism|nucleoside bisphosphate degradation|nucleoside bisphosphate breakdown The chemical reactions and pathways resulting in the breakdown of a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar. GO:0033868 obsolete Goodpasture-antigen-binding protein kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033868 MetaCyc:2.7.11.9-RXN|EC:2.7.11.9 ATP:Goodpasture antigen-binding protein phosphotransferase activity|GPBP kinase activity|GPBPK|Goodpasture antigen-binding protein kinase activity|STK11 OBSOLETE. Catalysis of the reaction: ATP + Goodpasture antigen-binding protein = ADP + Goodpasture antigen-binding phosphoprotein. GO:0033867 Fas-activated serine/threonine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033867 EC:2.7.11.8|MetaCyc:2.7.11.8-RXN FAST|ATP:Fas-activated serine/threonine protein phosphotransferase activity|FASTK|STK10 Catalysis of the reaction: ATP + Fas-activated serine/threonine protein = ADP + Fas-activated serine/threonine phosphoprotein. GO:0033866 nucleoside bisphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033866 nucleoside bisphosphate anabolism|nucleoside bisphosphate formation|nucleoside bisphosphate biosynthesis|nucleoside bisphosphatehate synthesis The chemical reactions and pathways resulting in the formation of a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar. GO:0033865 nucleoside bisphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033865 nucleoside bisphosphate metabolism The chemical reactions and pathways involving a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar. GO:0043234 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043234 GO:0043233 organelle lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043233 The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen. GO:0043236 laminin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043236 laminin-4 binding|laminin-2 binding Interacting selectively and non-covalently with laminins, glycoproteins that are major constituents of the basement membrane of cells. GO:0043235 receptor complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0043235 Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. GO:0043230 extracellular organelle biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0043230 Organized structure of distinctive morphology and function, occurring outside the cell. Includes, for example, extracellular membrane vesicles (EMVs) and the cellulosomes of anaerobic bacteria and fungi. GO:0043232 intracellular non-membrane-bounded organelle biolink:CellularComponent go-plus goslim_mouse|goslim_pir http://purl.obolibrary.org/obo/GO_0043232 intracellular non-membrane-enclosed organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes. GO:0043231 intracellular membrane-bounded organelle biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0043231 intracellular membrane-enclosed organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. CHEBI:138569 (3E,5Z)-dodecadienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138569 GO:0043238 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043238 GO:0018227 peptidyl-S-12-hydroxyfarnesyl-L-cysteine biosynthetic process from peptidyl-cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018227 RESID:AA0103 peptidyl-S-12-hydroxyfarnesyl-L-cysteine formation from peptidyl-cysteine|peptidyl-S-12-hydroxyfarnesyl-L-cysteine synthesis from peptidyl-cysteine|peptidyl-S-12-hydroxyfarnesyl-L-cysteine anabolism from peptidyl-cysteine The modification of peptidyl-cysteine to form S-12-hydroxyfarnesyl-L-cysteine; formation of S-farnesycysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CXXX motif and methyl esterification of the farnesylated cysteine. GO:0018226 peptidyl-S-farnesyl-L-cysteine biosynthetic process from peptidyl-cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018226 RESID:AA0102 peptidyl-S-farnesyl-L-cysteine formation from peptidyl-cysteine|peptidyl-S-farnesyl-L-cysteine synthesis from peptidyl-cysteine|peptidyl-S-farnesyl-L-cysteine anabolism from peptidyl-cysteine The modification of peptidyl-cysteine to form peptidyl-S-farnesyl-L-cysteine; formation of S-farnesycysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CXXX motif and methyl esterification of the farnesylated cysteine; the residue may be found at the first position in the sequence motif C-X-X-(SAQCMT)* where the second and third positions are usually aliphatic. GO:0043237 laminin-1 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043237 laminin-111 binding Interacting selectively and non-covalently with laminin-1, a glycoprotein trimer with the subunit composition alpha1, beta1, gamma1. GO:0018229 peptidyl-L-cysteine methyl ester biosynthetic process from peptidyl-cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018229 RESID:AA0105 peptidyl-L-cysteine methyl ester formation from peptidyl-cysteine|peptidyl-L-cysteine methyl ester synthesis from peptidyl-cysteine|peptidyl-L-cysteine methyl ester anabolism from peptidyl-cysteine The modification of a C-terminal peptidyl-cysteine to form peptidyl-L-cysteine methyl ester. GO:0043239 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043239 GO:0018228 peptidyl-S-geranylgeranyl-L-cysteine biosynthetic process from peptidyl-cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018228 RESID:AA0104 peptidyl-S-geranylgeranyl-L-cysteine formation from peptidyl-cysteine|peptidyl-S-geranylgeranyl-L-cysteine synthesis from peptidyl-cysteine|peptidyl-S-geranylgeranyl-L-cysteine anabolism from peptidyl-cysteine The modification of peptidyl-cysteine to form peptidyl-S-geranylgeranylcysteine; formation of S-geranylgeranyl-L-cysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CAAX motif and methyl esterification of the geranylgeranylated cysteine; methyl esterification but not cleavage occurs for the CXC motif. For the type II geranylgeranyltransferase the residue may be found at the first and final positions in the sequence motif C-X-C* or at the final position in the sequence motif C-C*. These motifs are necessary but not sufficient for modification. GO:0033864 positive regulation of NAD(P)H oxidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033864 upregulation of NAD(P)H oxidase activity|stimulation of NAD(P)H oxidase activity|up-regulation of NAD(P)H oxidase activity|activation of NAD(P)H oxidase activity|up regulation of NAD(P)H oxidase activity Any process that activates or increases the activity of the enzyme NAD(P)H oxidase. GO:0018223 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018223 GO:0018222 peptidyl-L-cysteine methyl disulfide biosynthetic process from peptidyl-cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018222 RESID:AA0101 peptidyl-L-cysteine methyl disulfide synthesis from peptidyl-cysteine|peptidyl-L-cysteine methyl disulphide biosynthetic process from peptidyl-cysteine|peptidyl-L-cysteine methyl disulphide biosynthesis from peptidyl-cysteine|peptidyl-L-cysteine methyl disulfide anabolism from peptidyl-cysteine|peptidyl-L-cysteine methyl disulfide formation from peptidyl-cysteine The modification of peptidyl-cysteine to form peptidyl-L-cysteine methyl disulfide. GO:0033863 ribose 1,5-bisphosphate phosphokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033863 RHEA:20109|KEGG_REACTION:R06836|EC:2.7.4.23|MetaCyc:2.7.4.23-RXN ATP:ribose-1,5-bisphosphate phosphotransferase activity|ribose 1,5-bisphosphokinase activity|PhnN Catalysis of the reaction: D-ribose 1,5-diphosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + ADP + H(+). GO:0033862 UMP kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033862 RHEA:24400|EC:2.7.4.22|MetaCyc:2.7.4.22-RXN UMPK|uridine monophosphate kinase activity|PyrH|ATP:UMP phosphotransferase activity|SmbA|UMP-kinase activity Catalysis of the reaction: ATP + UMP = ADP + UDP. CHEBI:138560 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138560 GO:0018225 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018225 CHEBI:2150 5beta-dihydrotestosterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_2150 GO:0033861 negative regulation of NAD(P)H oxidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033861 inhibition of NAD(P)H oxidase activity|down-regulation of NAD(P)H oxidase activity|downregulation of NAD(P)H oxidase activity|down regulation of NAD(P)H oxidase activity Any process that stops or reduces the activity of the enzyme NAD(P)H oxidase. GO:0018224 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018224 GO:0033860 regulation of NAD(P)H oxidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033860 Any process that modulates the activity of the enzyme NAD(P)H oxidase. GO:0018221 peptidyl-serine palmitoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018221 RESID:AA0080 peptidyl-serine O-palmitoylation The covalent attachment of a palmitoyl group to an oxygen (O) atom in a serine residue to form peptidyl-O-palmitoyl-L-serine. GO:0018220 peptidyl-threonine palmitoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018220 RESID:AA0079 peptidyl-threonine O-palmitoylation The covalent attachment of a palmitoyl group to an oxygen (O) atom in a threonine residue to form peptidyl-O-palmitoyl-L-threonine. GO:0033859 furaldehyde metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033859 The chemical reactions and pathways involving furaldehyde, a furan ring-containing aldehyde compound which can be formed from the thermal decomposition of biomass. GO:0033858 N-acetylgalactosamine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033858 EC:2.7.1.157|RHEA:12617|MetaCyc:2.7.1.157-RXN ATP:N-acetyl-D-galactosamine 1-phosphotransferase activity|GALK2|N-acetylgalactosamine (GalNAc)-1-phosphate kinase activity|GK2|GalNAc kinase activity Catalysis of the reaction: ATP + N-acetyl-D-galactosamine = ADP + N-acetyl-alpha-D-galactosamine 1-phosphate. GO:0033857 diphosphoinositol-pentakisphosphate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033857 EC:2.7.4.24 VIP2|VIP1|PPIP5K|PPIP5K2|PPIP5K1|PP-InsP5 kinase activity|PP-IP5 kinase activity|ATP:5-diphospho-1D-myo-inositol-pentakisphosphate phosphotransferase activity Catalysis of the reaction: ATP + 1D-myo-inositol 5-diphosphate pentakisphosphate = ADP + 1D-myo-inositol bisdiphosphate tetrakisphosphate. GO:0033856 pyridoxine 5'-phosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033856 RHEA:15265|EC:2.6.99.2|MetaCyc:PDXJ-RXN|KEGG_REACTION:R05838 PNP synthase activity|PdxJ|1-deoxy-D-xylulose-5-phosphate:3-amino-2-oxopropyl phosphate 3-amino-2-oxopropyltransferase (phosphate-hydrolysing; cyclizing) activity|pyridoxine 5-phosphate phospho lyase activity Catalysis of the reaction: 1-deoxy-D-xylulose 5-phosphate + 3-amino-2-oxopropyl phosphate = 2 H(2)O + H(+) + phosphate + pyridoxine 5'-phosphate. GO:0033855 nicotianamine aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033855 KEGG_REACTION:R07277|EC:2.6.1.80|MetaCyc:2.6.1.80-RXN|RHEA:22104 NAAT-I|NAAT-III|nicotianamine transaminase activity|NAAT-II|nicotianamine:2-oxoglutarate aminotransferase activity|NAAT Catalysis of the reaction: 2-oxoglutarate + nicotianamine = 3''-deamino-3''-oxonicotianamine + L-glutamate. GO:0033854 glutamate-prephenate aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033854 RHEA:22880|KEGG_REACTION:R07276|MetaCyc:PREPHENATE-TRANSAMINE-RXN|EC:2.6.1.79 L-glutamate:prephenate aminotransferase activity|PAT|prephenate transaminase activity|L-arogenate:2-oxoglutarate aminotransferase activity Catalysis of the reaction: 2-oxoglutarate + L-arogenate = L-glutamate + prephenate. GO:0043245 extraorganismal space biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043245 The environmental space outside of an organism; this may be a host organism in the case of parasitic and symbiotic organisms. GO:0043244 regulation of protein-containing complex disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043244 regulation of protein complex disassembly Any process that modulates the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components. GO:0043247 telomere maintenance in response to DNA damage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043247 DNA damage response, telomere maintenance Any process that occur in response to the presence of critically short or damaged telomeres. GO:0043246 megasome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043246 Large, cysteine proteinase rich lysosomes, often found in the amastigote (an intracytoplasmic, nonflagellated form of the parasite) stage of Leishmania species belonging to the mexicana complex. GO:0043241 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043241 GO:0043240 Fanconi anaemia nuclear complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043240 Fanconi anaemia complex|FA core complex|FA nuclear complex|FA complex A protein complex composed of the Fanconi anaemia (FA) proteins including A, C, E, G and F (FANCA-F). Functions in the activation of the downstream protein FANCD2 by monoubiquitylation, and is essential for protection against chromosome breakage. GO:0043243 positive regulation of protein-containing complex disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043243 upregulation of protein complex disassembly|up regulation of protein complex disassembly|activation of protein complex disassembly|stimulation of protein complex disassembly|positive regulation of protein complex disassembly|up-regulation of protein complex disassembly Any process that activates or increases the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components. GO:0043242 negative regulation of protein-containing complex disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043242 down regulation of protein complex disassembly|downregulation of protein complex disassembly|down-regulation of protein complex disassembly|negative regulation of protein complex disassembly|inhibition of protein complex disassembly Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components. GO:0043249 erythrocyte maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043249 RBC maturation|red blood cell maturation A developmental process, independent of morphogenetic (shape) change, that is required for an erythrocyte to attain its fully functional state. GO:0018238 peptidyl-lysine carboxyethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018238 RESID:AA0115 protein amino acid carboxyethylation The modification of peptidyl-lysine to form peptidyl-N6-1-carboxyethyl-L-lysine. GO:0043248 proteasome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043248 proteasome maturation|proteasome complex assembly|26S proteasome assembly The aggregation, arrangement and bonding together of a mature, active proteasome complex. GO:0018237 urease activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018237 urease activase activity Increases the activity of urease by promoting the incorporation of nickel into the active site. GO:0018239 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018239 GO:0018234 peptide cross-linking via 3'-(S-L-cysteinyl)-L-tyrosine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018234 RESID:AA0113 The thioether cross-linking of a cysteine residue to a tyrosine residue to form 3'-(S-L-cysteinyl)-L-tyrosine, found in galactose oxidase. GO:0033853 aspartate-prephenate aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033853 MetaCyc:PREPHENATE-ASP-TRANSAMINE-RXN|RHEA:20445|EC:2.6.1.78 L-arogenate:oxaloacetate aminotransferase activity|PAT|L-aspartate:prephenate aminotransferase activity|prephenate aspartate aminotransferase activity|prephenate transaminase activity Catalysis of the reaction: L-arogenate + oxaloacetate = prephenate + L-aspartate. GO:0033852 thyroid-hormone transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033852 RHEA:19133|EC:2.6.1.26|MetaCyc:THYROID-HORMONE-AMINOTRANSFERASE-RXN|KEGG_REACTION:R03952 thyroid hormone aminotransferase activity|3,5-dinitrotyrosine transaminase activity|thyroid-hormone aminotransferase activity|3,5-dinitrotyrosine aminotransferase activity|L-3,5,3'-triiodothyronine:2-oxoglutarate aminotransferase activity Catalysis of the reaction: 2-oxoglutarate + 3,5,3'-triiodo-L-thyronine = 3,5,3'-triiodothyropyruvate + L-glutamate. GO:0018233 peptide cross-linking via 2'-(S-L-cysteinyl)-L-histidine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018233 RESID:AA0109 The modification of peptidyl-histidine and peptidyl-cysteine to form a 2'-(S-L-cysteinyl)-L-histidine protein cross-link. GO:0033851 lavandulyl diphosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033851 KEGG_REACTION:R08950|MetaCyc:2.5.1.69-RXN|EC:2.5.1.69|RHEA:21676 dimethylallyl-diphosphate:dimethylallyl-diphosphate dimethylallyltransferase (lavandulyl-diphosphate-forming) activity|FDS-5 Catalysis of the reaction: 2 dimethylallyl diphosphate = diphosphate + lavandulyl diphosphate. GO:0018236 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018236 GO:0033850 Z-farnesyl diphosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033850 MetaCyc:2.5.1.68-RXN|EC:2.5.1.68|KEGG_REACTION:R08528|RHEA:23300 (Z)-farnesyl diphosphate synthase activity|geranyl-diphosphate:isopentenyl-diphosphate geranylcistransferase activity Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = 2-cis,6-trans-farnesyl diphosphate + diphosphate. GO:0018235 peptidyl-lysine carboxylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018235 RESID:AA0114 The modification of peptidyl-lysine to form peptidyl-N6-carboxy-L-lysine. GO:0018230 peptidyl-L-cysteine S-palmitoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018230 RESID:AA0106 peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|peptidyl-cysteine S-palmitoylation|peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine The covalent attachment of a palmitoyl group to a sulfur (S) atom within a cysteine residue to form peptidyl-S-palmitoyl-L-cysteine. CHEBI:2164 6-acetamido-3-aminohexanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_2164 GO:0018232 peptide cross-linking via S-(L-isoglutamyl)-L-cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018232 RESID:AA0108 The modification of peptidyl-glutamine and peptidyl-cysteine to form a S-(L-isoglutamyl)-L-cysteine protein cross-link. GO:0018231 peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018231 RESID:AA0107 peptidyl-S-diacylglycerol-L-cysteine formation from peptidyl-cysteine|peptidyl-S-diacylglycerol-L-cysteine synthesis from peptidyl-cysteine|peptidyl-S-diacylglycerol-L-cysteine anabolism from peptidyl-cysteine The modification of peptidyl-cysteine to form peptidyl-S-diacylglycerol-L-cysteine; the oleate and palmitate actually represent mixtures of saturated (generally at 3') and unsaturated (generally at 2') fatty acids. CHEBI:2165 6-acetamido-3-oxohexanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_2165 GO:0033849 chrysanthemyl diphosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033849 EC:2.5.1.67|KEGG_REACTION:R08948|RHEA:14009|MetaCyc:2.5.1.67-RXN CPPase activity|dimethylallyl-diphosphate:dimethylallyl-diphosphate dimethylallyltransferase (chrysanthemyl-diphosphate-forming) activity Catalysis of the reaction: 2 dimethylallyl diphosphate = (R,R)-chrysanthemyl diphosphate + diphosphate. GO:0043250 sodium-dependent organic anion transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043250 Enables the transfer of organic anions from one side of a membrane to the other, in a sodium dependent manner. GO:0033848 N2-(2-carboxyethyl)arginine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033848 RHEA:10556|EC:2.5.1.66|KEGG_REACTION:R05465|MetaCyc:2.5.1.66-RXN glyceraldehyde-3-phosphate:L-arginine N2-(2-hydroxy-3-oxopropyl) transferase (2-carboxyethyl-forming) activity|CEAS|N2-(2-carboxyethyl)arginine synthetase activity|glyceraldehyde-3-phosphate:L-arginine 2-N-(2-hydroxy-3-oxopropyl) transferase (2-carboxyethyl-forming) activity|CEA synthetase activity Catalysis of the reaction: D-glyceraldehyde 3-phosphate + L-arginine = N(2)-(2-carboxyethyl)-L-arginine + H(+) + phosphate. GO:0033847 O-phosphoserine sulfhydrylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033847 EC:2.5.1.65|RHEA:10252|MetaCyc:2.5.1.65-RXN O-phosphoserine(thiol)-lyase activity|O-phospho-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase activity Catalysis of the reaction: O-phospho-L-serine + hydrogen sulfide = L-cysteine + phosphate. GO:0033846 adenosyl-fluoride synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033846 MetaCyc:2.5.1.63-RXN|EC:2.5.1.63|RHEA:16661 fluorinase activity|S-adenosyl-L-methionine:fluoride adenosyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + fluoride = 5'-deoxy-5'-fluoroadenosine + L-methionine. GO:0008889 glycerophosphodiester phosphodiesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008889 EC:3.1.4.46|Reactome:R-HSA-1483107|Reactome:R-HSA-1483116|MetaCyc:GLYCPDIESTER-RXN|RHEA:12969 gene hpd protein|IgD-binding protein D|glycerophosphoryl diester phosphodiesterase activity|glycerophosphodiester glycerophosphohydrolase activity Catalysis of the reaction: a glycerophosphodiester + H2O = an alcohol + sn-glycerol 3-phosphate. GO:0033845 hydroxymethylfurfural reductase (NADPH) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033845 Catalysis of the reaction: 5-hydroxymethylfurfural + NADPH + H+ = 2,5-bis-hydroxymethylfuran + NADP+. UBERON:0005826 gracile fasciculus of spinal cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005826 gracile fascicle of spinal cord|spinal cord segment of fasciculus gracilis|spinal cord segment of gracile fasciculus|fasciculus gracilis (medulla spinalis) A gracile fasciculus that is part of a spinal cord. GO:0008888 glycerol dehydrogenase [NAD+] activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008888 RHEA:13769|KEGG_REACTION:R01034|EC:1.1.1.6|MetaCyc:GLYCDEH-RXN NAD-linked glycerol dehydrogenase activity|glycerol dehydrogenase activity Catalysis of the reaction: glycerol + NAD(+) = glycerone + H(+) + NADH. GO:0033844 galactose-6-sulfurylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033844 MetaCyc:2.5.1.5-RXN|EC:2.5.1.5 galactose-6-sulfatase activity|D-galactose-6-sulfate:alkyltransferase (cyclizing) activity|galactose 6-sulfatase activity|porphyran sulfatase activity Catalysis of the elimination of sulfate from the D-galactose 6-sulfate residues of porphyran, producing 3,6-anhydrogalactose residues. GO:0008887 glycerate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008887 RHEA:23516|KEGG_REACTION:R01514|EC:2.7.1.31|Reactome:R-HSA-6799495|MetaCyc:GLY3KIN-RXN D-glyceric acid kinase activity|GK|D-glycerate 3-kinase activity|glycerate-3-kinase activity|D-glycerate kinase activity|glycerate kinase (phosphorylating)|ATP:D-glycerate 2-phosphotransferase activity|ATP:(R)-glycerate 3-phosphotransferase activity Catalysis of the reaction: D-glycerate + ATP = 3-phospho-D-glycerate + ADP + 2 H(+). GO:0033843 xyloglucan 6-xylosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033843 EC:2.4.2.39|MetaCyc:2.4.2.39-RXN xyloglucan 6-alpha-D-xylosyltransferase activity|UDP-D-xylose:xyloglucan 1,6-alpha-D-xylosyltransferase activity|uridine diphosphoxylose-xyloglucan 6alpha-xylosyltransferase activity Catalysis of the transfer of an alpha-D-xylosyl residue from UDP-D-xylose to a glucose residue in xyloglucan, forming an alpha-1,6-D-xylosyl-D-glucose linkage. GO:0043256 laminin complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0043256 A large, extracellular glycoprotein complex composed of three different polypeptide chains, alpha, beta and gamma. Provides an integral part of the structural scaffolding of basement membranes. GO:0008886 glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008886 RHEA:14669|KEGG_REACTION:R01058|MetaCyc:1.2.1.9-RXN|EC:1.2.1.9 glyceraldehyde 3-phosphate dehydrogenase (NADP)|dehydrogenase, glyceraldehyde phosphate (nicotinamide adenine dinucleotide phosphate)|NADP-glyceraldehyde phosphate dehydrogenase|glyceraldehyde phosphate dehydrogenase (NADP)|glyceraldehyde-3-phosphate:NADP reductase activity|D-glyceraldehyde-3-phosphate:NADP+ oxidoreductase activity|nonphosphorylating glyceraldehyde-3-phosphate dehydrogenase activity|glyceraldehyde-3-phosphate dehydrogenase (NADP)|NADP-glyceraldehyde-3-phosphate dehydrogenase activity|triosephosphate dehydrogenase activity Catalysis of the reaction: D-glyceraldehyde 3-phosphate + H(2)O + NADP(+) = 3-phospho-D-glycerate + 2 H(+) + NADPH. GO:0043255 regulation of carbohydrate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043255 regulation of carbohydrate biosynthesis|regulation of carbohydrate anabolism|regulation of carbohydrate synthesis|regulation of carbohydrate formation Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of carbohydrates. GO:0008885 glutathionylspermidine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008885 EC:6.3.1.8|RHEA:21272|MetaCyc:GSPSYN-RXN GSP synthetase activity|gamma-L-glutamyl-L-cysteinyl-glycine:spermidine ligase (ADP-forming) activity|gamma-L-glutamyl-L-cysteinyl-glycine:spermidine ligase (ADP-forming) [spermidine is numbered so that atom N-1 is in the amino group of the aminopropyl part of the molecule]|glutathione:spermidine ligase (ADP-forming) activity|glutathionylspermidine synthetase activity Catalysis of the reaction: gamma-L-glutamyl-L-cysteinyl-glycine + spermidine + ATP = N1-(gamma-L-glutamyl-L-cysteinyl-glycyl)-spermidine + ADP + phosphate. GO:0008884 glutathionylspermidine amidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008884 EC:3.5.1.78|RHEA:17173|MetaCyc:GSPAMID-RXN gamma-L-glutamyl-L-cysteinyl-glycine:spermidine amidase activity|glutathionylspermidine amidohydrolase (spermidine-forming) activity|GSP amidase activity Catalysis of the reaction: N1-(gamma-L-glutamyl-L-cysteinyl-glycyl)-spermidine + H2O = gamma-L-glutamyl-L-cysteinyl-glycine + spermidine. GO:0043258 laminin-9 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043258 laminin-421 complex A laminin complex composed of alpha4, beta2 and gamma1 polypeptide chains. GO:0043257 laminin-8 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043257 laminin-411 complex A laminin complex composed of alpha4, beta1 and gamma1 polypeptide chains. GO:0008883 glutamyl-tRNA reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008883 EC:1.2.1.70|RHEA:12344|MetaCyc:GLUTRNAREDUCT-RXN|KEGG_REACTION:R04109 L-glutamate-semialdehyde: NADP+ oxidoreductase (L-glutamyl-tRNAGlu-forming) Catalysis of the reaction: (S)-4-amino-5-oxopentanoate + NADP(+) + tRNA(Glu) = L-glutamyl-tRNA(Glu) + H(+) + NADPH. GO:0008882 [glutamate-ammonia-ligase] adenylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008882 RHEA:18589|EC:2.7.7.42|MetaCyc:GSADENYLATION-RXN glutamate-ammonia-ligase adenylyltransferase activity|ATP:glutamine synthetase adenylyltransferase activity|ATP:L-glutamate:ammonia ligase (ADP-forming) adenylyltransferase activity|ATP:[glutamate-ammonia-ligase] adenylyltransferase activity|glutamine-synthetase adenylyltransferase activity|adenosine triphosphate:glutamine synthetase adenylyltransferase activity Catalysis of the reaction: ATP + [L-glutamate:ammonia ligase (ADP-forming)] = diphosphate + adenylyl-[L-glutamate:ammonia ligase (ADP-forming)]. GO:0043252 sodium-independent organic anion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043252 The directed, sodium-independent, movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0043251 sodium-dependent organic anion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043251 The directed, sodium-dependent, movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0008881 glutamate racemase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008881 KEGG_REACTION:R00260|EC:5.1.1.3|MetaCyc:GLUTRACE-RXN|RHEA:12813 Catalysis of the reaction: L-glutamate = D-glutamate. GO:0008880 glucuronate isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008880 EC:5.3.1.12|RHEA:13049|MetaCyc:GLUCUROISOM-RXN D-glucuronate ketol-isomerase activity|uronic acid isomerase activity|uronate isomerase activity|uronic isomerase activity|D-glucuronate aldose-ketose-isomerase activity|D-glucuronate isomerase activity Catalysis of the reaction: D-glucuronate = D-fructuronate. GO:0043254 regulation of protein-containing complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043254 regulation of protein complex assembly Any process that modulates the frequency, rate or extent of protein complex assembly. GO:0043253 chloroplast ribosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043253 A ribosome contained within a chloroplast. GO:0018209 peptidyl-serine modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018209 The modification of peptidyl-serine. GO:0018208 peptidyl-proline modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018208 The modification of peptidyl-proline. GO:0018205 peptidyl-lysine modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018205 The modification of peptidyl-lysine. GO:0043259 laminin-10 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043259 laminin-511 complex A laminin complex composed of alpha5, beta1 and gamma1 polypeptide chains. GO:0018204 peptidyl-leucine modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018204 The modification of peptidyl-leucine. GO:0018207 peptidyl-phenylalanine modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018207 The modification of peptidyl-phenylalanine. GO:0018206 peptidyl-methionine modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018206 The modification of peptidyl-methionine. GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033842 MetaCyc:2.4.1.244-RXN|RHEA:20493|EC:2.4.1.244 UDP-N-acetyl-D-galactosamine:N-acetyl-D-glucosaminyl-group beta-1,4-N-acetylgalactosaminyltransferase activity|beta1,4-N-acetylgalactosaminyltransferase III activity|beta4GalNAc-T4|beta4GalNAc-T3|beta1,4-N-acetylgalactosaminyltransferase IV activity|beta1,4-N-acetylgalactosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + N-acetyl-beta-D-glucosaminyl group = UDP + N-acetyl-beta-D-galactosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl group. UBERON:0005835 cuneate fasciculus of spinal cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005835 cuneate fasciculus|fasciculus cuneatus medullae spinalis|tract of Burdach|burdach's tract|fasciculus cuneatus|cuneate fascicle of spinal cord An axon tract in the spinal cord which primarily transmits information from the forelimb and trunk. It is part of the posterior column-medial lemniscus pathway. GO:0018201 peptidyl-glycine modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018201 The modification of peptidyl-glycine. GO:0033841 6G-fructosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033841 MetaCyc:2.4.1.243-RXN|EC:2.4.1.243 6G-FT|fructan:fructan 6G-fructosyltransferase activity|1F-oligo[beta-D-fructofuranosyl-(2->1)-]sucrose 6G-beta-D-fructotransferase activity|6G-FFT|6G-fructotransferase activity Catalysis of the reaction: [1-beta-D-fructofuranosyl-(2->1)-]m+1 alpha-D-glucopyranoside + [1-beta-D-fructofuranosyl-(2->1)-]n+1 alpha-D-glucopyranoside = [1-beta-D-fructofuranosyl-(2->1)-]m alpha-D-glucopyranoside + [1-beta-D-fructofuranosyl-(2->1)-]n+1 beta-D-fructofuranosyl-(2->6)-alpha-D-glucopyranoside (m > 0; n >= 0). GO:0018200 peptidyl-glutamic acid modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018200 The modification of peptidyl-glutamic acid. GO:0033840 NDP-glucose-starch glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033840 RHEA:15873|MetaCyc:2.4.1.242-RXN|EC:2.4.1.242 starch synthase II activity|waxy protein|GBSSI|granule-bound starch synthase activity|starch granule-bound nucleoside diphosphate glucose-starch glucosyltransferase activity|NDPglucose-starch glucosyltransferase activity|granule-bound starch synthase I activity|GBSS|GBSSII|NDP-glucose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity|granule-bound starch synthase II activity Catalysis of the reaction: NDP-glucose + (1,4-alpha-D-glucosyl)n = NDP + (1,4-alpha-D-glucosyl)n+1. GO:0018203 peptidyl-isoleucine modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018203 The modification of peptidyl-isoleucine. GO:0018202 peptidyl-histidine modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018202 The modification of peptidyl-histidine. UBERON:0005832 cuneate fasciculus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005832 cuneatus tract|fasciculus cuneus|cuneate column|fasciculus cuneatus|cuneate tract|cuneate fascicle An axon tract in the spinal cord and medulla which primarily transmits information from the forelimb and trunk. It is part of the dorsal column-medial lemniscus pathway. GO:0033839 flavonol-3-O-glycoside glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033839 RHEA:23544|MetaCyc:2.4.1.240-RXN|EC:2.4.1.240 UDP-glucose:flavonol-3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside 2'''-O-beta-D-glucosyltransferase activity Catalysis of the reaction: UDP-glucose + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside = UDP + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside. GO:0033838 flavonol-3-O-glucoside glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033838 MetaCyc:2.4.1.239-RXN|EC:2.4.1.239|RHEA:18893 UDP-glucose:flavonol-3-O-glucoside 2''-O-beta-D-glucosyltransferase activity Catalysis of the reaction: UDP-glucose + a flavonol 3-O-beta-D-glucoside = UDP + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside. GO:0043261 laminin-12 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043261 laminin-213 complex A laminin complex composed of alpha2, beta1 and gamma3 polypeptide chains. GO:0033837 anthocyanin 3'-O-beta-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033837 MetaCyc:2.4.1.238-RXN|EC:2.4.1.238|RHEA:35627 UDP-glucose:anthocyanin 3'-O-glucosyltransferase activity|UDP-glucose:anthocyanin 3'-O-beta-D-glucosyltransferase activity|3'GT Catalysis of the reaction: UDP-glucose + an anthocyanin = UDP + an anthocyanin 3'-O-beta-D-glucoside. GO:0033836 flavonol 7-O-beta-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033836 MetaCyc:2.4.1.237-RXN|EC:2.4.1.237|RHEA:23164 UDP-glucose:flavonol 7-O-glucosyltransferase activity|UDP-glucose:flavonol 7-O-beta-D-glucosyltransferase activity Catalysis of the reaction: UDP-glucose + a flavonol = UDP + a flavonol 7-O-beta-D-glucoside. GO:0043260 laminin-11 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043260 laminin-521 complex A laminin complex composed of alpha5, beta2 and gamma1 polypeptide chains. GO:0033835 flavanone 7-O-glucoside 2''-O-beta-L-rhamnosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033835 EC:2.4.1.236|RHEA:15473|MetaCyc:RXN-7759|MetaCyc:RXN-5004|MetaCyc:RXN-9699|MetaCyc:RXN-5002|MetaCyc:RXN-5001 UDP-rhamnose:flavanone-7-O-glucoside-2''-O-rhamnosyltransferase activity|1->2 UDP-rhamnosyltransferase activity|UDP-L-rhamnose:flavanone-7-O-glucoside 2''-O-beta-L-rhamnosyltransferase activity Catalysis of the reaction: UDP-L-rhamnose + a flavanone 7-O-glucoside = UDP + a flavanone 7-O-[beta-L-rhamnosyl-(1->2)-beta-D-glucoside]. GO:0033834 kaempferol 3-O-galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033834 MetaCyc:2.4.1.234-RXN|EC:2.4.1.234|RHEA:15709 UDP-galactose:kaempferol 3-O-beta-D-galactosyltransferase activity|F3GalTase activity Catalysis of the reaction: UDP-galactose + kaempferol = UDP + kaempferol 3-O-beta-D-galactoside. GO:0008899 homoserine O-succinyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008899 MetaCyc:HOMSUCTRAN-RXN|EC:2.3.1.46|KEGG_REACTION:R01777|RHEA:22008 homoserine O-transsuccinylase activity|succinyl-CoA:L-homoserine O-succinyltransferase activity|homoserine succinyltransferase activity Catalysis of the reaction: L-homoserine + succinyl-CoA = O-succinyl-L-homoserine + CoA. GO:0033833 hydroxymethylfurfural reductase (NADH) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033833 MetaCyc:RXN-10738 Catalysis of the reaction: 5-hydroxymethylfurfural + NADH + H+ = 2,5-bis-hydroxymethylfuran + NAD+. GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008898 RHEA:21820|MetaCyc:HOMOCYSTEINE-S-METHYLTRANSFERASE-RXN S-adenosyl-L-methionine:L-homocysteine methyltransferase activity|L-homocysteine S-methyltransferase activity|S-adenosyl-L-methionine:L-homocysteine S-methyltransferase activity|homocysteine transmethylase activity|S-adenosylmethionine homocysteine transmethylase activity|adenosylmethionine:homocysteine methyltransferase activity|S-adenosylmethionine:homocysteine methyltransferase activity|homocysteine methyltransferase activity|adenosylmethionine transmethylase activity|S-adenosylmethionine-homocysteine transmethylase activity Catalysis of the reaction: S-adenosyl-L-methionine + L-homocysteine = S-adenosyl-L-homocysteine + L-methionine. GO:0033832 alpha,alpha-trehalose phosphorylase (configuration-retaining) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033832 RHEA:16257|MetaCyc:RXN-4441 alpha,alpha-trehalose:phosphate alpha-D-glucosyltransferase activity|trehalose phosphorylase activity Catalysis of the reaction: alpha,alpha-trehalose + phosphate = alpha-D-glucose + alpha-D-glucose 1-phosphate. UBERON:0005814 arch of atlas biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005814 atlas arch A vertebral arch that is part of the first cervical vertebra GO:0008897 holo-[acyl-carrier-protein] synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008897 EC:2.7.8.7|Reactome:R-HSA-199202|RHEA:12068|MetaCyc:HOLO-ACP-SYNTH-RXN AcpS|alphaaminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase activity|holo-ACP synthase activity|phosphopantetheinyltransferase activity|alpha-aminoadipate reductase phosphopantetheinyl transferase activity|phosphopantetheinyl transferase|CoA:apo-acyl-carrier-protein pantetheinephosphotransferase activity|CoA-[4'-phosphopantetheine]:apo-acyl-carrier-protein 4'-pantetheinephosphotransferase activity|acyl carrier protein synthetase activity|acyl carrier protein holoprotein (holo-ACP) synthetase activity|alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase activity|P-pant transferase activity|holo-[peptidyl-carrier protein] synthase activity|holo-ACP synthetase activity|holo-acyl-carrier-protein synthase activity|holo-[acyl-carrier-protein] synthase activity|PPTase activity|coenzyme A:fatty acid synthetase apoenzyme 4'-phosphopantetheine transferase activity|holosynthase activity|4'-phosphopantetheinyl transferase activity|ACPS activity|L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase activity|acyl carrier protein synthase activity|4'-phosphopantetheinyltransferase activity Catalysis of the reaction: CoA + substrate-serine = adenosine 3',5'-bisphosphate + substrate-serine-4'-phosphopantetheine. The transfer of the 4'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form. GO:0043267 negative regulation of potassium ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043267 transmembrane conductance regulator activity|regulation of potassium conductance|negative regulation of potassium ion conductance|down regulation of potassium ion transport|downregulation of potassium ion transport|regulation of K+ conductance|down-regulation of potassium ion transport|negative regulation of K+ transport|inhibition of potassium ion transport|negative regulation of potassium transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0043266 regulation of potassium ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043266 regulation of K+ transport|regulation of potassium conductance|regulation of potassium transport|regulation of K+ conductance|regulation of potassium ion conductance Any process that modulates the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0008896 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008896 GO:0043269 regulation of ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043269 Any process that modulates the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0008895 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008895 GO:0008894 guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008894 EC:3.6.1.40|RHEA:13073|MetaCyc:PPPGPPHYDRO-RXN guanosine 5'-triphosphate-3'-diphosphate 5'-phosphohydrolase activity|guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase activity|guanosine 5'-triphosphate 3'-diphosphate 5'-phosphatase activity|guanosine-5'-triphosphate,3'-diphosphate 5'-phosphohydrolase activity|guanosine pentaphosphate phosphatase activity|guanosine pentaphosphate phosphohydrolase activity|guanosine pentaphosphatase activity|pppGpp 5'-phosphohydrolase activity Catalysis of the reaction: guanosine 5'-triphosphate,3'-diphosphate + H2O = guanosine 5'-diphosphate,3'-diphosphate + phosphate. GO:0043268 positive regulation of potassium ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043268 positive regulation of potassium ion conductance|upregulation of potassium ion transport|positive regulation of potassium conductance|positive regulation of K+ conductance|up regulation of potassium ion transport|activation of potassium ion transport|stimulation of potassium ion transport|positive regulation of potassium transport|positive regulation of K+ transport|up-regulation of potassium ion transport Any process that activates or increases the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0008893 guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008893 MetaCyc:PPGPPSYN-RXN|EC:3.1.7.2|RHEA:14253 guanosine-3',5'-bis(diphosphate) 3'-diphosphohydrolase activity|guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase activity|penta-phosphate guanosine-3'-diphosphohydrolase activity|penta-phosphate guanosine-3'-pyrophosphohydrolase activity|(ppGpp)ase activity|guanosine-3',5'-bis(diphosphate) 3'-pyrophosphatase activity|PpGpp-3'-pyrophosphohydrolase activity|PpGpp phosphohydrolase activity Catalysis of the reaction: guanosine 3',5'-bis(diphosphate) + H2O = guanosine 5'-diphosphate + diphosphate. GO:0043263 cellulosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043263 Wikipedia:Cellulosome scaffoldin complex An extracellular multi-enzyme complex containing up to 11 different enzymes aligned on a non-catalytic scaffolding glycoprotein. Functions to hydrolyze cellulose. GO:0043262 adenosine-diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043262 MetaCyc:APYRASE-RXN|RHEA:61436 ATP-diphosphatase activity|adenosine diphosphatase activity|ATP diphosphohydrolase activity|ADPase activity|ADPase Catalysis of the reaction: ADP + H2O = AMP + phosphate. GO:0008892 guanine deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008892 Reactome:R-HSA-74255|RHEA:14665|EC:3.5.4.3|MetaCyc:GUANINE-DEAMINASE-RXN guanase activity|guanine aminase activity|GAH activity|guanine aminohydrolase activity Catalysis of the reaction: guanine + H2O = xanthine + NH3. GO:0008891 glycolate oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008891 Reactome:R-HSA-389842|RHEA:25311|MetaCyc:RXN-969 Catalysis of the reaction: glycolate + O2 = glyoxylate + hydrogen peroxide. GO:0043265 ectoplasm biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043265 Granule free cytoplasm, lying immediately below the plasma membrane. GO:0043264 extracellular non-membrane-bounded organelle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043264 extracellular non-membrane-enclosed organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring outside the cell. GO:0008890 glycine C-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008890 EC:2.3.1.29|RHEA:20736|KEGG_REACTION:R00371|MetaCyc:AKBLIG-RXN 2-amino-3-ketobutyrate coenzyme A ligase activity|2-amino-3-ketobutyrate-CoA ligase activity|glycine acetyltransferase activity|acetyl-CoA:glycine C-acetyltransferase activity|aminoacetone synthase activity|2-amino-3-ketobutyrate CoA ligase activity Catalysis of the reaction: acetyl-CoA + glycine = L-2-amino-3-oxobutanoate + CoA + H(+). GO:0018219 peptidyl-cysteine S-acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018219 RESID:AA0056 The acetylation of peptidyl-cysteine to form peptidyl-S-acetyl-L-cysteine. CHEBI:138558 (3E,5Z)-dodecadienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138558 GO:0018216 peptidyl-arginine methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018216 The addition of a methyl group to an arginine residue in a protein. GO:0018215 protein phosphopantetheinylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018215 protein amino acid phosphopantetheinylation The modification of a protein amino acid by phosphopantetheinylation. GO:0018218 peptidyl-cysteine phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018218 RESID:AA0034 The phosphorylation of peptidyl-cysteine to form peptidyl-S-phospho-L-cysteine. GO:0018217 peptidyl-aspartic acid phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018217 The phosphorylation of peptidyl-aspartic acid. GO:0018212 peptidyl-tyrosine modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018212 The modification of peptidyl-tyrosine. GO:0033831 kojibiose phosphorylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033831 RHEA:11176|MetaCyc:2.4.1.230-RXN|KEGG_REACTION:R07264|EC:2.4.1.230 2-alpha-D-glucosyl-D-glucose:phosphate beta-D-glucosyltransferase activity Catalysis of the reaction: kojibiose + phosphate = beta-D-glucose 1-phosphate + D-glucose. GO:0033830 Skp1-protein-hydroxyproline N-acetylglucosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033830 EC:2.4.1.229|RHEA:17841 UDP-GlcNAc:Skp1-hydroxyproline GlcNAc-transferase activity|Skp1-HyPro GlcNAc-transferase activity|UDP-N-acetyl-D-glucosamine:Skp1-protein-hydroxyproline N-acetyl-D-glucosaminyl-transferase activity|UDP-GlcNAc:hydroxyproline polypeptide GlcNAc-transferase activity|UDP-N-acetylglucosamine (GlcNAc):hydroxyproline polypeptide GlcNAc-transferase activity Catalysis of the reaction: UDP-N-acetylglucosamine + Skp1-protein-hydroxyproline = UDP + Skp1-protein-O-(N-acetyl-D-glucosaminyl)hydroxyproline. GO:0018211 peptidyl-tryptophan modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018211 The chemical alteration of a tryptophan residue in a peptide. GO:0018214 protein carboxylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018214 protein amino acid carboxylation The addition of a carboxy group to a protein amino acid. UBERON:0005821 gracile fasciculus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005821 gracile column|f. gracilis medullae spinalis|gracilis tract|gracile fascicle|gracile tract|fasciculus gracilis|tract of Goll A group of axons that are from neurons involved in proprioception from the lower trunk and lower limb[GO]. The fasciculus gracilis (tract of Goll) is a bundle of axon fibres in the dorsomedial spinal cord that carries information about fine touch, vibrations, and conscious proprioception from the lower part of the body to the brain stem. It is part of the posterior column of the spinal cord, which also contains the fasciculus cuneatus, which carries the same information from the upper part of the body. This tract and its continuation in the brain stem is often referred to as the posterior column-medial lemniscus pathway. The fasciculus gracilis is wedge-shaped on transverse section and lies next the posterior median septum, its base being at the surface of the medulla spinalis, and its apex directed toward the posterior gray commissure. It increases in size from below upward, and consists of long thin fibers that are derived from the posterior nerve roots, and ascend as far as the medulla oblongata, where they end in the nucleus gracilis. The tract of Goll was named after Swiss neuroanatomist Friedrich Goll[WP]. GO:0018213 peptidyl-valine modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018213 The modification of peptidyl-valine. GO:0018210 peptidyl-threonine modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018210 The modification of peptidyl-threonine. GO:0043270 positive regulation of ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043270 upregulation of ion transport|up regulation of ion transport|activation of ion transport|stimulation of ion transport|up-regulation of ion transport Any process that activates or increases the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0033828 glucosylglycerol-phosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033828 KEGG_REACTION:R05328|MetaCyc:2.4.1.213-RXN|RHEA:12881|EC:2.4.1.213 ADP-glucose:sn-glycerol-3-phosphate 2-beta-D-glucosyltransferase activity|GG-phosphate synthase activity|glucosyl-glycerol-phosphate synthase activity|ADPglucose:sn-glycerol-3-phosphate 2-beta-D-glucosyltransferase activity|GGPS Catalysis of the reaction: sn-glycerol 3-phosphate + ADP-glucose = 2-O-(beta-D-glucosyl)-sn-glycerol 3-phosphate + ADP + H(+). GO:0033827 high-mannose-oligosaccharide beta-1,4-N-acetylglucosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033827 EC:2.4.1.197|MetaCyc:2.4.1.197-RXN acetylglucosamine-oligosaccharide acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-oligosaccharide acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:high-mannose-oligosaccharide beta-1,4-N-acetylglucosaminyltransferase activity|UDP-GlcNAc:oligosaccharide beta-N-acetylglucosaminyltransferase activity Catalysis of the transfer of an N-acetyl-D-glucosamine residue from UDP-N-acetyl-D-glucosamine to the 4-position of a mannose linked alpha-1,6 to the core mannose of high-mannose oligosaccharides produced by Dictyostelium discoideum. GO:0033826 xyloglucan 4-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033826 MetaCyc:2.4.1.168-RXN|EC:2.4.1.168 uridine diphosphoglucose-xyloglucan 4beta-glucosyltransferase activity|UDPglucose:xyloglucan 1,4-beta-D-glucosyltransferase activity|xyloglucan glucosyltransferase activity|UDP-glucose:xyloglucan 1,4-beta-D-glucosyltransferase activity|xyloglucan 4beta-D-glucosyltransferase activity Catalysis of the transfer of a beta-D-glucosyl residue from UDP-glucose on to a glucose residue in xyloglucan, forming a beta-1,4-D-glucosyl-D-glucose linkage. GO:0043272 ethylene biosynthesis involved in jasmonic acid and ethylene-dependent systemic resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043272 ethylene anabolism during jasmonic acid and ethylene-dependent systemic resistance|ethylene biosynthetic process during jasmonic acid and ethylene-dependent systemic resistance|ethylene synthesis during jasmonic acid and ethylene-dependent systemic resistance|ethylene formation during jasmonic acid and ethylene-dependent systemic resistance The chemical reactions and pathways resulting in the formation of ethylene (C2-H4, ethene), occurring as part of the process of jasmonic acid and ethylene-dependent systemic resistance. UBERON:0005808 bone tissue of long bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005808 osseous tissue of long bone A bone tissue that is part of a long bone. GO:0008869 galactonate dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008869 RHEA:18649|KEGG_REACTION:R03033|EC:4.2.1.6|MetaCyc:GALACTONDEHYDRAT-RXN D-galactonate dehydratase activity|D-galactonate hydro-lyase activity|D-galactonate hydro-lyase (2-dehydro-3-deoxy-D-galactonate-forming)|D-galactonate dehydrase activity Catalysis of the reaction: D-galactonate = 2-dehydro-3-deoxy-D-galactonate + H(2)O. GO:0033825 oligosaccharide 4-alpha-D-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033825 EC:2.4.1.161|MetaCyc:2.4.1.161-RXN 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity|1,4-alpha-glucan:1,4-alpha-glucan 4-alpha-glucosyltransferase activity|amylase III activity Catalysis of the transfer of the non-reducing terminal alpha-D-glucose residue from a 1,4-alpha-D-glucan to the 4-position of an alpha-D-glucan, thus bringing about the hydrolysis of oligosaccharides. GO:0043271 negative regulation of ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043271 down regulation of ion transport|downregulation of ion transport|down-regulation of ion transport|inhibition of ion transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0033824 alternansucrase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033824 EC:2.4.1.140|MetaCyc:2.4.1.140-RXN sucrose:1,6(1,3)-alpha-D-glucan 6(3)-alpha-D-glucosyltransferase activity|sucrose-1,6(3)-alpha-glucan 6(3)-alpha-glucosyltransferase activity|sucrose:1,6-, 1,3-alpha-D-glucan 3-alpha- and 6-alpha-D-glucosyltransferase activity Catalysis of the transfer of an alpha-D-glucosyl residue from sucrose to alternately the 6-position and the 3-position of the non-reducing terminal residue of an alpha-D-glucan, thus producing a glucan having alternating alpha-1,6- and alpha-1,3-linkages. GO:0008868 galactitol-1-phosphate 5-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008868 RHEA:15137|MetaCyc:1.1.1.251-RXN|EC:1.1.1.251 galactitol-1-phosphate:NAD+ oxidoreductase activity Catalysis of the reaction: galactitol-1-phosphate + NAD+ = D-tagatose 6-phosphate + NADH + H+. UBERON:0005806 portal system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005806 portal venous system In the circulatory system of animals, a portal venous system occurs when a capillary bed drains into another capillary bed through veins, without first going through the heart. Both capillary beds and the blood vessels that connect them are considered part of the portal venous system. They are relatively uncommon as the majority of capillary beds drain into veins which then drain into the heart, not into another capillary bed. Portal venous systems are considered venous because the blood vessels that join the two capillary beds are either veins or venules. Examples of such systems include the hepatic portal system and the hypophyseal portal system. Unqualified, 'portal venous system' often refers to the hepatic portal system. For this reason, 'portal vein' most commonly refers to the hepatic portal vein[WP]. GO:0008867 galactarate dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008867 KEGG_REACTION:R05608|EC:4.2.1.42|RHEA:16005|MetaCyc:GALACTARDEHYDRA-RXN D-galactarate hydro-lyase activity|D-galactarate hydro-lyase (5-dehydro-4-deoxy-D-glucarate-forming) Catalysis of the reaction: galactarate = 5-dehydro-4-deoxy-D-glucarate + H(2)O. GO:0033823 procollagen glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033823 EC:2.4.1.66|RHEA:12576|Reactome:R-HSA-1981157|MetaCyc:PROCOLLAGEN-GLUCOSYLTRANSFERASE-RXN galactosylhydroxylysine glucosyltransferase activity|uridine diphosphoglucose-collagen glucosyltransferase activity|UDP-glucose-collagenglucosyltransferase activity|collagen glucosyltransferase activity|UDPglucose:5-(D-galactosyloxy)-L-lysine-procollagen D-glucosyltransferase activity|galactosylhydroxylysyl glucosyltransferase activity|galactosylhydroxylysine-glucosyltransferase activity|UDP-glucose:5-(D-galactosyloxy)-L-lysine-procollagen D-glucosyltransferase activity|collagen hydroxylysyl glucosyltransferase activity Catalysis of the reaction: UDP-glucose + 5-(D-galactosyloxy)-L-lysine-procollagen = UDP + 1,2-D-glucosyl-5-D-(galactosyloxy)-L-lysine-procollagen. UBERON:0005805 dorsal aorta biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005805 DA|dorsal aortae|dorsal aorta root|aorta dorsalis|aortae dorsales|dorsal aortic root|dorsal aortæ The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once. GO:0033822 glucosyl-DNA beta-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033822 EC:2.4.1.28|MetaCyc:2.4.1.28-RXN T6-glucosyl-HMC-beta-glucosyl transferase activity|UDPglucose:D-glucosyl-DNA beta-D-glucosyltransferase activity|uridine diphosphoglucose-glucosyldeoxyribonucleate beta-glucosyltransferase activity|UDP-glucose:D-glucosyl-DNA beta-D-glucosyltransferase activity|T6-beta-glucosyl transferase activity Catalysis of the transfer of a beta-D-glucosyl residue from UDP-glucose to a glucosylhydroxymethylcytosine residue in DNA. GO:0008866 fructuronate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008866 RHEA:15729|KEGG_REACTION:R02454|MetaCyc:MANNONOXIDOREDUCT-RXN|EC:1.1.1.57 mannonate oxidoreductase activity|D-mannonate oxidoreductase activity|mannonic dehydrogenase activity|D-mannonate:NAD oxidoreductase activity|D-mannonate dehydrogenase activity|D-mannonate:NAD+ 5-oxidoreductase activity Catalysis of the reaction: D-mannonate + NAD(+) = D-fructuronate + H(+) + NADH. GO:0008865 fructokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008865 EC:2.7.1.4|RHEA:16125|MetaCyc:FRUCTOKINASE-RXN D-fructose(D-mannose)kinase activity|D-fructokinase activity|fructokinase (phosphorylating)|ATP:D-fructose 6-phosphotransferase activity Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 6-phosphate. GO:0033821 DNA beta-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033821 EC:2.4.1.27|MetaCyc:2.4.1.27-RXN UDPglucose:DNA beta-D-glucosyltransferase activity|uridine diphosphoglucose-deoxyribonucleate beta-glucosyltransferase activity|T4-HMC-beta-glucosyl transferase activity|UDP-glucose:DNA beta-D-glucosyltransferase activity|T4 phage beta-glucosyltransferase activity|T4-beta-glucosyl transferase activity|UDP glucose-DNA beta-glucosyltransferase activity Catalysis of the transfer of a beta-D-glucosyl residue from UDP-glucose to a hydroxymethylcytosine residue in DNA. GO:0008864 formyltetrahydrofolate deformylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008864 KEGG_REACTION:R00944|EC:3.5.1.10|RHEA:19833|MetaCyc:FORMYLTHFDEFORMYL-RXN formyltetrahydrofolate hydrolase activity|formyl-FH(4) hydrolase activity|10-formyltetrahydrofolate amidohydrolase activity Catalysis of the reaction: 10-formyltetrahydrofolate + H(2)O = (6S)-5,6,7,8-tetrahydrofolate + formate + H(+). GO:0043278 response to morphine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043278 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a morphine stimulus. Morphine is an opioid alkaloid, isolated from opium, with a complex ring structure. GO:0008863 formate dehydrogenase (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008863 UM-BBD_reactionID:r0103|MetaCyc:FORMATEDEHYDROG-RXN|EC:1.17.1.9|RHEA:15985|MetaCyc:1.2.1.2-RXN|KEGG_REACTION:R00519 formate hydrogenlyase|FDH I|formic acid dehydrogenase|formate:NAD+ oxidoreductase|N-FDH|formate benzyl-viologen oxidoreductase|NAD-formate dehydrogenase|NAD-dependent formate dehydrogenase|formate-NAD oxidoreductase|formate dehydrogenase (NAD)|formic hydrogen-lyase|FDH II|NAD-linked formate dehydrogenase Catalysis of the reaction: formate + NAD(+) = CO(2) + NADH. GO:0043277 apoptotic cell clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043277 apoptotic cell removal|efferocytosis|programmed cell clearance The recognition and removal of an apoptotic cell by a neighboring cell or by a phagocyte. GO:0008862 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008862 GO:0008861 formate C-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008861 RHEA:11844|EC:2.3.1.54|MetaCyc:PYRUVFORMLY-RXN acetyl-CoA:formate C-acetyltransferase activity|pyruvate formate:lyase activity|pyruvic formate-lyase activity|pyruvate formate-lyase activity|formate acetyltransferase activity|PFL Catalysis of the reaction: acetyl-CoA + formate = CoA + pyruvate. GO:0043279 response to alkaloid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043279 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active. GO:0043274 phospholipase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043274 Interacting selectively and non-covalently with any phospholipase, enzymes that catalyze of the hydrolysis of a glycerophospholipid. GO:0008860 ferredoxin-NAD+ reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008860 EC:1.18.1.3|RHEA:16521|MetaCyc:FERREDOXIN--NAD+-REDUCTASE-RXN NAD-ferredoxin reductase activity|ferredoxin-linked NAD reductase activity|ferredoxin:NAD+ oxidoreductase activity|NADH flavodoxin oxidoreductase activity|NADH-ferredoxin oxidoreductase activity|ferredoxin-nicotinamide adenine dinucleotide reductase activity|ferredoxin-NAD reductase activity|NADH2-ferredoxin oxidoreductase activity|reductase, reduced nicotinamide adenine dinucleotide-ferredoxin|NADH-ferredoxinTOL reductase (component of toluene dioxygenase)|NADH-ferredoxinNAP reductase (component of naphthalene dioxygenase multicomponent enzyme system)|NADH-ferredoxin reductase activity Catalysis of the reaction: reduced ferredoxin + NAD+ = oxidized ferredoxin + NADH + H+. CHEBI:44278 N-acetyl-alpha-D-glucosamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_44278 GO:0043273 CTPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043273 cytidine triphosphatase activity|single-stranded DNA-dependent CTPase activity|CTPase activity, coupled Catalysis of the reaction: CTP + H2O = CDP + phosphate. May or may not be coupled to another reaction. GO:0043276 anoikis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043276 Wikipedia:Anoikis suspension induced apoptosis|detachment induced cell death Apoptosis triggered by inadequate or inappropriate adherence to substrate e.g. after disruption of the interactions between normal epithelial cells and the extracellular matrix. GO:0043275 obsolete glutamate carboxypeptidase II activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043275 pteroylpolyglutamate hydrolase activity|glutamate carboxypeptidase II activity|membrane glutamate carboxypeptidase|NAALA dipeptidase activity|N-acetylated alpha-linked acidic dipeptidase activity|prostrate-specific membrane antigen|pteroylpoly-gamma-glutamate hydrolase activity|pteroylpolygammaglutamyl hydrolase activity|folate hydrolase activity|N-acetylated-gamma-linked-acidic dipeptidase activity|mGCP|prostate-specific membrane antigen|N-acetylated-gamma-linked-acidic dipeptidase (NAALADase)|N-acetylated-alpha-linked-amino dipeptidase activity|pteroylpolyglutamic acid hydrolase activity|pteroylpoly-gamma-glutamate carboxypeptidase activity|rat NAAG peptidase|NAALADase activity|folylpolyglutamate hydrolase activity|acetylaspartylglutamate dipeptidase activity|PSM antigen|PSMA|microsomal gamma-glutamyl carboxypeptidase OBSOLETE. Catalysis of the reaction: N-acetyl-L-Asp-L-Glu + H2O = N-acetyl-L-Asp + L-Glu. GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033829 Reactome:R-HSA-5096538|MetaCyc:2.4.1.222-RXN|Reactome:R-HSA-1912355|EC:2.4.1.222 O-fucosylpeptide beta-1,3-N-acetylglucosaminyltransferase activity|UDP-D-GlcNAc:O-L-fucosylpeptide 3-beta-N-acetyl-D-glucosaminyltransferase activity Catalysis of the transfer of a beta-D-GlcNAc residue from UDP-D-GlcNAc to the fucose residue of a fucosylated protein acceptor. UBERON:0005813 tubercle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005813 A round nodule, small eminence, or warty outgrowth found on bones, skin, or within the lungs in tuberculosis. They are also found on the leading edge of Humpback Whale's flippers, improving fluid flow over the flipper's surface[WP]. GO:0033820 DNA alpha-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033820 EC:2.4.1.26|MetaCyc:2.4.1.26-RXN T6-HMC-alpha-glucosyl transferase activity|T4-HMC-alpha-glucosyl transferase activity|T2-HMC-alpha-glucosyl transferase activity|uridine diphosphoglucose-deoxyribonucleate alpha-glucosyltransferase activity|UDP-glucose:DNA alpha-D-glucosyltransferase activity|UDPglucose-DNA alpha-glucosyltransferase activity Catalysis of the transfer of an alpha-D-glucosyl residue from UDP-glucose to a hydroxymethylcytosine residue in DNA. GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043281 regulation of caspase activation|regulation of caspase activity Any process that modulates the activity of a cysteine-type endopeptidase involved in apoptosis. GO:0033817 beta-ketoacyl-acyl-carrier-protein synthase II activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033817 RHEA:14565|MetaCyc:2.3.1.179-RXN|EC:2.3.1.179 KAS II|FabF|beta-ketoacyl-ACP synthase II activity|KASII|(Z)-hexadec-11-enoyl-acyl-carrier-protein:malonyl-acyl-carrier-protein C-acyltransferase (decarboxylating) activity|3-oxoacyl-acyl carrier protein synthase I activity Catalysis of the reaction: (Z)-hexadec-11-enoyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = (Z)-3-oxooctadec-13-enoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]. GO:0033816 diaminobutyrate acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033816 MetaCyc:R102-RXN|KEGG_REACTION:R06978|RHEA:16901|EC:2.3.1.178 acetyl-CoA:L-2,4-diaminobutanoate 4-N-acetyltransferase activity|diaminobutyric acid acetyltransferase activity|DAB acetyltransferase activity|2,4-diaminobutanoate acetyltransferase activity|L-2,4-diaminobutanoate acetyltransferase activity|DABA acetyltransferase activity|L-2,4-diaminobutyrate acetyltransferase activity|DABAcT|acetyl-CoA:L-2,4-diaminobutanoate N4-acetyltransferase activity|EctA Catalysis of the reaction: L-2,4-diaminobutyrate + acetyl-CoA = N(4)-acetyl-L-2,4-diaminobutyrate + CoA + H(+). GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043280 up regulation of caspase activity|positive regulation of caspase activity|upregulation of caspase activity|stimulation of caspase activity|activation of caspase activity|up-regulation of caspase activity Any process that activates or increases the activity of a cysteine-type endopeptidase involved in the apoptotic process. GO:0033815 biphenyl synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033815 MetaCyc:2.3.1.177-RXN|RHEA:22292|EC:2.3.1.177 malonyl-CoA:benzoyl-CoA malonyltransferase activity|BIS Catalysis of the reaction: 3 malonyl-CoA + benzoyl-CoA = 4 CoA + 3,5-dihydroxybiphenyl + 4 CO2. GO:0043283 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043283 GO:0033814 propanoyl-CoA C-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033814 RHEA:16865|MetaCyc:2.3.1.176-RXN|EC:2.3.1.176 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA:propanoyl-CoA C-acyltransferase activity|PTE-2|SCPchi|peroxisomal thiolase 2 activity|sterol carrier protein-chi|sterol carrier protein-X|SCP-X Catalysis of the reaction: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA + propanoyl-CoA = CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA. GO:0043282 pharyngeal muscle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043282 The process whose specific outcome is the progression of the pharyngeal muscle over time, from its formation to the mature structure. A pharyngeal muscle is any muscle that forms part of the pharynx. GO:0008879 glucose-1-phosphate thymidylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008879 MetaCyc:DTDPGLUCOSEPP-RXN|KEGG_REACTION:R02328|RHEA:15225|EC:2.7.7.24 glucose 1-phosphate thymidylyltransferase activity|dTDP-glucose synthase activity|dTTP:alpha-D-glucose-1-phosphate thymidylyltransferase activity|thymidine diphosphoglucose pyrophosphorylase activity|dTDP-glucose pyrophosphorylase activity|dTDP-glucose diphosphorylase activity|TDP-glucose pyrophosphorylase activity|thymidine diphosphate glucose pyrophosphorylase activity Catalysis of the reaction: alpha-D-glucose 1-phosphate + dTTP = diphosphate + dTDP-glucose. GO:0033813 deacetylcephalosporin-C acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033813 RHEA:23860|KEGG_REACTION:R03064|MetaCyc:2.3.1.175-RXN|EC:2.3.1.175 cefG|deacetylcephalosporin C acetyltransferase activity|DAC-AT|acetyl-CoA:deacetylcephalosporin-C acetyltransferase activity|acetyl-CoA:deacetylcephalosporin-C O-acetyltransferase activity|acetyl coenzyme A:DAC acetyltransferase activity|acetyl-CoA:DAC acetyltransferase activity|acetyl-CoA:DAC O-acetyltransferase activity|CPC acetylhydrolase activity|DAC acetyltransferase activity Catalysis of the reaction: acetyl-CoA + deacetylcephalosporin C = cephalosporin C + CoA. GO:0008878 glucose-1-phosphate adenylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008878 MetaCyc:GLUC1PADENYLTRANS-RXN|KEGG_REACTION:R00948|EC:2.7.7.27|RHEA:12120 ADGase activity|ADP-glucose pyrophosphorylase activity|ADP-glucose diphosphorylase activity|ADP:alpha-D-glucose-1-phosphate adenylyltransferase activity|ADP-glucose synthetase activity|adenosine diphosphate glucose pyrophosphorylase activity|ADP glucose pyrophosphorylase activity|ADPG pyrophosphorylase activity|ATP:alpha-D-glucose-1-phosphate adenylyltransferase activity|ATP:alpha-glucose-1-phosphate adenylyl transferase activity|glucose 1-phosphate adenylyltransferase activity|ADP-glucose synthase activity|adenosine diphosphoglucose pyrophosphorylase activity Catalysis of the reaction: alpha-D-glucose 1-phosphate + ATP = ADP-glucose + diphosphate. GO:0033812 3-oxoadipyl-CoA thiolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033812 EC:2.3.1.174|RHEA:19481|MetaCyc:RXN-3641 succinyl-CoA:acetyl-CoA C-succinyltransferase activity Catalysis of the reaction: succinyl-CoA + acetyl-CoA = CoA + 3-oxoadipyl-CoA. GO:0033811 flavonol-3-O-triglucoside O-coumaroyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033811 RHEA:22160|MetaCyc:2.3.1.173-RXN|EC:2.3.1.173 4-coumaroyl-CoA:flavonol-3-O-[beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside] 6'''-O-4-coumaroyltransferase activity Catalysis of the reaction: 4-coumaroyl-CoA + a flavonol 3-O-[beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside] = CoA + a flavonol 3-O-[6-(4-coumaroyl)-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside]. GO:0008877 glucose-1-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008877 KEGG_REACTION:R00304|MetaCyc:GLUCOSE-1-PHOSPHAT-RXN|EC:3.1.3.10|RHEA:19933 alpha-D-glucose-1-phosphate phosphohydrolase activity|D-glucose-1-phosphate phosphohydrolase activity Catalysis of the reaction: alpha-D-glucose 1-phosphate + H2O = D-glucose + phosphate. GO:0008876 quinoprotein glucose dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008876 MetaCyc:GLUCDEHYDROG-RXN|RHEA:22152|EC:1.1.5.2 D-glucose:(pyrroloquinoline-quinone) 1-oxidoreductase activity|D-glucose:ubiquinone oxidoreductase activity|glucose dehydrogenase (pyrroloquinoline-quinone) activity|glucose dehydrogenase (PQQ-dependent) activity|quinoprotein D-glucose dehydrogenase activity Catalysis of the reaction: D-glucose + ubiquinone = D-glucono-1,5-lactone + ubiquinol. GO:0033810 anthocyanin 5-O-glucoside 6'''-O-malonyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033810 MetaCyc:2.3.1.172-RXN|EC:2.3.1.172|RHEA:21988 malonyl-CoA:pelargonidin-3-O-(6-caffeoyl-beta-D-glucoside)-5-O-beta-D-glucoside 6'''-O-malonyltransferase activity|Ss5MaT1 Catalysis of the reaction: malonyl-CoA + pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside = CoA + 4'''-demalonylsalvianin. GO:0043289 apocarotenoid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043289 apocarotenoid synthesis|apocarotenoid formation|apocarotenoid biosynthesis|apo carotenoid biosynthetic process|apocarotenoid anabolism The chemical reactions and pathways resulting in the formation of apocarotenoids by the oxidative cleavage of carotenoids. Many apocarotenoids are biologically important e.g. retinal and abscisic acid. GO:0008875 gluconate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008875 Catalysis of the reaction: D-gluconate + NADP+ = dehydro-D-gluconate + NADPH + H+. GO:0043288 apocarotenoid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043288 apo carotenoid metabolic process|apocarotenoid metabolism The chemical reactions and pathways involving apocarotenoids, a class of compounds derived from the oxidative cleavage of carotenoids, many of which are biologically important e.g. retinal and abscisic acid. GO:0008874 gluconate 5-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008874 EC:1.1.1.69|MetaCyc:GLUCONATE-5-DEHYDROGENASE-RXN 5-ketogluconate reductase activity|5-ketogluconate 5-reductase activity|5-keto-D-gluconate reductase|D-gluconate:NAD(P)+ 5-oxidoreductase|5-keto-D-gluconate 5-reductase activity Catalysis of the reaction: D-gluconate + NADP+ = 5-dehydro-D-gluconate + NADPH + H+. GO:0008873 gluconate 2-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008873 MetaCyc:1.1.1.215-RXN|RHEA:16653|EC:1.1.1.215 2-keto-D-gluconate reductase activity|D-gluconate:NADP+ oxidoreductase activity|2-ketogluconate reductase activity Catalysis of the reaction: D-gluconate + NADP+ = 2-dehydro-D-gluconate + NADPH + H+. GO:0008872 glucarate dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008872 EC:4.2.1.40|RHEA:14573|MetaCyc:GLUCARDEHYDRA-RXN D-glucarate hydro-lyase (5-dehydro-4-deoxy-D-glucarate-forming)|D-glucarate dehydratase activity|D-glucarate hydro-lyase activity Catalysis of the reaction: D-glucarate = 5-dehydro-4-deoxy-D-glucarate + H2O. GO:0008871 aminoglycoside 2''-nucleotidyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008871 MetaCyc:2.7.7.46-RXN|EC:2.7.7.46 gentamicin 2''- adenylyltransferase activity|gentamicin 2''-nucleotidyltransferase activity|2''-aminoglycoside nucleotidyltransferase activity|NTP:gentamicin 2''-nucleotidyltransferase activity|gentamycin 2''-nucleotidyltransferase activity Catalysis of the reaction: nucleoside triphosphate + aminoglycoside = diphosphate + 2''-nucleotidylaminoglycoside. GO:0043285 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043285 GO:0008870 galactoside O-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008870 EC:2.3.1.18|RHEA:15713|MetaCyc:GALACTOACETYLTRAN-RXN galactoside acetyltransferase activity|thiogalactoside acetyltransferase activity|thiogalactoside transacetylase activity|acetyl-CoA:beta-D-galactoside 6-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + a beta-D-galactoside = CoA + a 6-acetyl-beta-D-galactoside. GO:0043284 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043284 GO:0043287 poly(3-hydroxyalkanoate) binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043287 PHA binding Interacting selectively and non-covalently with poly(3-hydroxyalkanoate)s, polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria. GO:0033819 lipoyl(octanoyl) transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033819 MetaCyc:RXN0-947|Reactome:R-HSA-6793590|EC:2.3.1.181 lipoyl (octanoyl)-acyl carrier protein:protein transferase activity|octanoyl-acyl carrier protein-protein N-octanoyltransferase activity|lipoyl (octanoyl)-acyl-carrier-protein-protein N-lipoyltransferase activity|octanoyl-acyl-carrier-protein-protein N-octanoyltransferase activity|lipoate/octanoate transferase activity|LipB|octanoyl-acyl-carrier-protein:protein N-octanoyltransferase activity Catalysis of the reaction: octanoyl-[acyl-carrier protein] + protein = protein N6-(octanoyl)lysine + acyl-carrier protein. GO:0033818 beta-ketoacyl-acyl-carrier-protein synthase III activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033818 RHEA:12080|MetaCyc:2.3.1.180-RXN|EC:2.3.1.180 acetyl-CoA:malonyl-acyl-carrier-protein C-acyltransferase activity|beta-ketoacyl (acyl carrier protein) synthase III activity|beta-ketoacyl-ACP synthase III activity|KASIII|3-ketoacyl-acyl carrier protein synthase III activity|KAS III|beta-ketoacyl-acyl carrier protein synthase III activity|3-oxoacyl:ACP synthase III activity|FabH Catalysis of the reaction: acetyl-CoA + malonyl-[acyl-carrier protein] = acetoacyl-[acyl-carrier protein] + CoA + CO2. GO:0043286 regulation of poly(3-hydroxyalkanoate) biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043286 regulation of poly(3-hydroxyalkanoate) formation|regulation of PHA|regulation of poly(3-hydroxyalkanoate) biosynthesis|regulation of poly(3-hydroxyalkanoate) anabolism|regulation of poly(3-hydroxyalkanoate) synthesis Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of poly(3-hydroxyalkanoates), polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria. CHEBI:138538 O-{S-[3-oxo-(11Z)-octadecenoyl]pantetheine-4'-phosphoryl}-L-serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138538 UBERON:0005800 section of aorta biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005800 portion of aorta|aortic segment|segment of aorta|aortic section Any portion of the aorta including the ascending and descending aorta, and aortic arch or a portion of the aortic orifice of the left ventricle. CHEBI:138532 lysophosphatidylethanolamine 17:0 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138532 CHEBI:83859 dalnigrein(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83859 CHEBI:83856 dalpatein(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83856 CHEBI:83866 N-acyl-D-galactosylsphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83866 CHEBI:83865 androst-5-ene-3,17-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83865 CHEBI:83864 (R)-lipoyl-AMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83864 CHEBI:83863 (25S)-3-ketocholest-4-en-26-al biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83863 CHEBI:83862 (25R)-3-ketocholest-4-en-26-al biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83862 CHEBI:83861 (25R)-26-hydroxycholest-4-en-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83861 CHEBI:83860 (25S)-26-hydroxycholest-4-en-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83860 CHEBI:246422 dUMP(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_246422 CHEBI:83876 cationic sphingoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83876 CHEBI:83875 N-acyl-(3-O-sulfo-D-galactosyl)sphingosine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83875 GO:0018292 molybdenum incorporation via L-cysteinyl molybdopterin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018292 RESID:AA0142 The incorporation of molybdenum into a protein via L-cysteinyl molybdopterin. GO:0018291 molybdenum incorporation into iron-sulfur cluster biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018291 molybdenum incorporation into iron-sulphur cluster The incorporation of molybdenum into an iron-sulfur cluster. GO:0018294 protein-FAD linkage via S-(8alpha-FAD)-L-cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018294 RESID:AA0143 The formation of a protein-FAD linkage via S-(8-alpha-FAD)-L-cysteine. GO:0018293 protein-FAD linkage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018293 The formation of a linkage between a protein amino acid and flavin-adenine dinucleotide (FAD). GO:0018290 iron and molybdenum incorporation into iron-molybdenum-sulfur cluster via L-cysteinyl homocitryl molybdenum-heptairon-nonasulfide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018290 RESID:AA0141 iron and molybdenum incorporation into iron-molybdenum-sulphur cluster via L-cysteinyl homocitryl molybdenum-heptairon-nonasulphide The incorporation of iron and molybdenum into a Mo-7Fe-8S iron-molybdenum-sulfur cluster via L-cysteinyl homocitryl molybdenum-heptairon-nonasulfide, found in nitrogenase. CHEBI:83898 UDP-N-acetyl-alpha-D-muramoyl-L-alaninate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83898 GO:0018289 molybdenum incorporation into metallo-sulfur cluster biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018289 molybdenum incorporation into metallo-sulphur cluster The incorporation of molybdenum into a metallo-sulfur cluster. GO:0018288 iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl tetrairon tetrasulfide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018288 RESID:AA0140 iron incorporation into iron-sulphur cluster via tetrakis-L-cysteinyl tetrairon tetrasulphide The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tetrakis-L-cysteinyl tetrairon tetrasulfide. GO:0018285 iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl diiron disulfide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018285 RESID:AA0137 iron incorporation into iron-sulphur cluster via tetrakis-L-cysteinyl diiron disulphide The incorporation of iron into a 2Fe-2S iron-sulfur cluster via tetrakis-L-cysteinyl diiron disulfide. GO:0018284 iron incorporation into protein via tetrakis-L-cysteinyl iron biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018284 RESID:AA0136 The incorporation of iron into a protein via tetrakis-L-cysteinyl iron (there is no exogenous sulfur, so this modification by itself does not produce an iron-sulfur protein). GO:0018287 iron incorporation into iron-sulfur cluster via tris-L-cysteinyl triiron tetrasulfide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018287 RESID:AA0139 iron incorporation into iron-sulphur cluster via tris-L-cysteinyl triiron tetrasulphide The incorporation of iron into a 3Fe-4S iron-sulfur cluster via tris-L-cysteinyl triiron tetrasulfide. GO:0018286 obsolete iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl triiron trisulfide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018286 iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl triiron trisulfide|iron incorporation into iron-sulphur cluster via tris-L-cysteinyl triiron trisulphide OBSOLETE. The incorporation of iron into a 3Fe-3S iron-sulfur cluster via hexakis-L-cysteinyl triiron trisulfide. The three-iron three-sulfur cluster probably does not exist except as an intermediate form. GO:0018299 iron incorporation into the Rieske iron-sulfur cluster via bis-L-cysteinyl bis-L-histidino diiron disulfide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018299 RESID:AA0225 iron incorporation into the Rieske iron-sulphur cluster via bis-L-cysteinyl bis-L-histidino diiron disulphide The incorporation of iron into a Rieske 4Fe-4S iron-sulfur cluster via bis-L-cysteinyl bis-L-histidino diiron disulfide. GO:0018296 protein-FAD linkage via O4'-(8alpha-FAD)-L-tyrosine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018296 RESID:AA0145 The formation of a protein-FAD linkage via O4'-(8-alpha-FAD)-L-tyrosine. GO:0018295 protein-FAD linkage via 3'-(8alpha-FAD)-L-histidine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018295 RESID:AA0144 The formation of a protein-FAD linkage via 3'-(8-alpha-FAD)-L-histidine. GO:0018298 protein-chromophore linkage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018298 The covalent or noncovalent attachment of a chromophore to a protein. GO:0018297 protein-FAD linkage via 1'-(8alpha-FAD)-L-histidine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018297 RESID:AA0221 The formation of a protein-FAD linkage via 1'-(8-alpha-FAD)-L-histidine. GO:0018270 GPI anchor biosynthetic process via N-alanyl-glycosylphosphatidylinositolethanolamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018270 RESID:AA0163 GPI anchor anabolism via N-alanyl-glycosylphosphatidylinositolethanolamine|GPI anchor synthesis via N-alanyl-glycosylphosphatidylinositolethanolamine|GPI anchor formation via N-alanyl-glycosylphosphatidylinositolethanolamine The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-alanine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of an alanyl-peptide bond in the carboxy-terminal region of a membrane-associated protein. GO:0018272 protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018272 RESID:AA0119 The modification of peptidyl-lysine to form N6-pyridoxal phosphate-L-lysine. GO:0018271 biotin-protein ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018271 EC:6.3.4.-|MetaCyc:BIOTINLIG-RXN|Reactome:R-HSA-9035987|Reactome:R-HSA-9035990|Reactome:R-HSA-2993814|Reactome:R-HSA-9035988|Reactome:R-HSA-2993447|Reactome:R-HSA-2993799|Reactome:R-HSA-4167511|Reactome:R-HSA-2993802|Reactome:R-HSA-3323184 biotin-apoprotein ligase activity Catalysis of the reaction: ATP + biotin + protein = AMP + diphosphate + biotin-protein. GO:0018267 GPI anchor biosynthetic process via N-cysteinyl-glycosylphosphatidylinositolethanolamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018267 RESID:AA0160 GPI anchor formation via N-cysteinyl-glycosylphosphatidylinositolethanolamine|GPI anchor synthesis via N-cysteinyl-glycosylphosphatidylinositolethanolamine|GPI anchor anabolism via N-cysteinyl-glycosylphosphatidylinositolethanolamine The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-cysteine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a cysteinyl-peptide bond in the carboxy-terminal region of a membrane-associated protein. GO:0018266 GPI anchor biosynthetic process via N-aspartyl-glycosylphosphatidylinositolethanolamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018266 RESID:AA0159 GPI anchor anabolism via N-aspartyl-glycosylphosphatidylinositolethanolamine|GPI anchor synthesis via N-aspartyl-glycosylphosphatidylinositolethanolamine|GPI anchor formation via N-aspartyl-glycosylphosphatidylinositolethanolamine The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-aspartic acid ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a aspartyl-peptide bond in the carboxy-terminal region of a membrane-associated protein. GO:0018269 GPI anchor biosynthetic process via N-seryl-glycosylphosphatidylinositolethanolamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018269 RESID:AA0162 GPI anchor anabolism via N-seryl-glycosylphosphatidylinositolethanolamine|GPI anchor formation via N-seryl-glycosylphosphatidylinositolethanolamine|GPI anchor synthesis via N-seryl-glycosylphosphatidylinositolethanolamine The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-serine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a seryl-peptide bond in the carboxy-terminal region of a membrane-associated protein. GO:0018268 GPI anchor biosynthetic process via N-glycyl-glycosylphosphatidylinositolethanolamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018268 RESID:AA0161 GPI anchor anabolism via N-glycyl-glycosylphosphatidylinositolethanolamine|GPI anchor synthesis via N-glycyl-glycosylphosphatidylinositolethanolamine|GPI anchor formation via N-glycyl-glycosylphosphatidylinositolethanolamine The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-glycine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a glycyl-peptide bond in the carboxy-terminal region of a membrane-associated protein. GO:0018263 isopeptide cross-linking via N-(L-isoaspartyl)-L-cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018263 RESID:AA0216 The formation of an isopeptide cross-link between peptidyl-asparagine and peptidyl-cysteine to produce N-(L-isoaspartyl)-L-cysteine. GO:0018262 isopeptide cross-linking biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018262 The formation of a covalent cross-link between or within peptide chains, where either the amino group or the carboxyl group, or both, are not attached to the alpha carbon. GO:0018265 GPI anchor biosynthetic process via N-asparaginyl-glycosylphosphatidylinositolethanolamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018265 RESID:AA0158 GPI anchor formation via N-asparaginyl-glycosylphosphatidylinositolethanolamine|GPI anchor synthesis via N-asparaginyl-glycosylphosphatidylinositolethanolamine|GPI anchor anabolism via N-asparaginyl-glycosylphosphatidylinositolethanolamine The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-asparagine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a asparaginyl-peptide bond in the carboxy-terminal region of a membrane-associated protein. GO:0018264 isopeptide cross-linking via N-(L-isoaspartyl)-glycine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018264 RESID:AA0126 The formation of an isopeptide cross-link between peptidyl-asparagine and peptidyl-glycine to produce N-(L-isoaspartyl)-glycine. GO:0018281 GSI anchor biosynthetic process via N-seryl-glycosylsphingolipidinositolethanolamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018281 RESID:AA0166 GSI anchor formation via N-seryl-glycosylsphingolipidinositolethanolamine|GSI anchor synthesis via N-seryl-glycosylsphingolipidinositolethanolamine|GSI anchor anabolism via N-seryl-glycosylsphingolipidinositolethanolamine The formation of a C-terminal peptidyl-serine ethanolamide-linked glycosylsphingolipidinositol (GSI) anchor following hydrolysis of a seryl-peptide bond in the carboxy-terminal region of a membrane-associated protein. GO:0018280 protein S-linked glycosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018280 protein amino acid S-linked glycosylation A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via a sulfur atom of a peptidyl-amino-acid such as cysteine or methionine. GO:0018283 iron incorporation into metallo-sulfur cluster biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018283 iron incorporation into metallo-sulphur cluster The incorporation of iron into a metallo-sulfur cluster. GO:0018282 metal incorporation into metallo-sulfur cluster biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018282 metal incorporation into metallo-sulphur cluster The formation of a cluster of several metal atoms, including iron, nickel, molybdenum, vanadium, or copper, with one or more bridging (mu-bond) sulfur atoms; amino acids residues in proteins that may ligate the metal sulfur cluster are cysteine, histidine, aspartate, glutamate, serine and cysteine persulfide. GO:0033899 ribonuclease U2 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033899 MetaCyc:3.1.27.4-RXN|EC:4.6.1.20 ribonuclease (purine) activity|pleospora RNase activity|purine-specific ribonuclease activity|trichoderma koningi RNase III activity|purine specific endoribonuclease activity|ribonuclease U2 activity|RNase U2 activity|purine-specific RNase activity Catalysis of the two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Ap or Gp with 2',3'-cyclic phosphate intermediates. GO:0033898 Bacillus subtilis ribonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033898 MetaCyc:3.1.27.2-RXN|EC:4.6.1.22 ribonucleate nucleotido-2'-transferase (cyclizing) activity|proteus mirabilis RNase activity Catalysis of the endonucleolytic cleavage to 2',3'-cyclic nucleotides. GO:0043201 response to leucine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043201 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leucine stimulus. GO:0043200 response to amino acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043200 response to amino acid stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups. GO:0043203 axon hillock biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043203 NIF_Subcellular:sao627227260|Wikipedia:Axon_hillock Portion of the neuronal cell soma from which the axon originates. GO:0043202 lysosomal lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043202 The volume enclosed within the lysosomal membrane. GO:0043209 myelin sheath biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043209 Wikipedia:Myelin|FMA:62983|NIF_Subcellular:sao593830697 astrocyte sheath|Schwann cell myelin sheath|oligodendrocyte myelin sheath An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system. GO:0043208 glycosphingolipid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043208 Interacting selectively and non-covalently with glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide. GO:0043205 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043205 GO:0043204 perikaryon biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043204 cell soma cytoplasm The portion of the cell soma (neuronal cell body) that excludes the nucleus. GO:0043207 response to external biotic stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043207 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things. GO:0043206 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043206 GO:0033897 ribonuclease T2 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033897 EC:4.6.1.19|MetaCyc:3.1.27.1-RXN ribonuclease II activity|RNase T2 activity|ribonucleate nucleotido-2'-transferase (cyclizing) activity|ribonuclease M activity|RNase Ms activity|RNase M activity|acid RNase activity|base-non-specific ribonuclease activity|RNase II activity|Escherichia coli ribonuclease I' ribonuclease PP2 activity|nonspecific RNase activity|ribonnuclease (non-base specific) activity|nonbase-specific RNase activity|RNAase CL activity|ribonuclease U4 activity|ribonuclease (non-base specific) activity|non-base specific ribonuclease activity|ribonucleate 3'-oligonucleotide hydrolase activity|ribonuclease N2 activity|ribonuclease PP3 activity|acid ribonuclease activity|RNase (non-base specific) activity|Escherichia coli ribonuclease II activity Catalysis of the two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates. GO:0018278 N-terminal peptidyl-threonine deamination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018278 RESID:AA0129 The deamination of N-terminal peptidyl-threonine to form peptidyl-2-oxobutanoic acid. GO:0018277 protein deamination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018277 protein amino acid deamination The removal of an amino group from a protein amino acid. GO:0033896 ribonuclease IX activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033896 MetaCyc:3.1.26.10-RXN|EC:3.1.26.10 poly(U)- and poly(C)-specific endoribonuclease activity Catalysis of the endonucleolytic cleavage of poly(U) or poly(C) to fragments terminated by 3'-hydroxy and 5'-phosphate groups. GO:0033895 ribonuclease [poly-(U)-specific] activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033895 EC:3.1.26.9 ribonuclease (uracil-specific) activity|uracil-specific endoribonuclease activity|uracil-specific RNase activity Catalysis of the endonucleolytic cleavage of poly(U) to fragments terminated by 3'-hydroxy and 5'-phosphate groups. GO:0033894 ribonuclease P4 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033894 EC:3.1.26.7|MetaCyc:3.1.26.7-RXN Catalysis of the endonucleolytic cleavage of RNA, removing 3'-extranucleotides from tRNA precursor. GO:0018279 protein N-linked glycosylation via asparagine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018279 protein amino acid N-linked glycosylation via asparagine The glycosylation of protein via the N4 atom of peptidyl-asparagine forming N4-glycosyl-L-asparagine; the most common form is N-acetylglucosaminyl asparagine; N-acetylgalactosaminyl asparagine and N4 glucosyl asparagine also occur. This modification typically occurs in extracellular peptides with an N-X-(ST) motif. Partial modification has been observed to occur with cysteine, rather than serine or threonine, in the third position; secondary structure features are important, and proline in the second or fourth positions inhibits modification. GO:0033893 ribonuclease IV activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033893 EC:3.1.26.6|MetaCyc:3.1.26.6-RXN endoribonuclease IV activity Catalysis of the endonucleolytic cleavage of poly(A) to fragments terminated by 3'-hydroxy and 5'-phosphate groups. GO:0018274 peptide cross-linking via L-lysinoalanine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018274 RESID:AA0123 The modification of peptidyl-lysine and peptidyl-serine to form a (2Xi,9S)-L-lysinoalanine cross-link. GO:0018273 protein-chromophore linkage via peptidyl-N6-retinal-L-lysine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018273 RESID:AA0120 The modification of peptidyl-lysine to form N6-retinal-L-lysine. GO:0033892 deoxyribonuclease (pyrimidine dimer) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033892 EC:3.1.25.1|MetaCyc:3.1.25.1-RXN T4 endonuclease V activity|bacteriophage T4 endodeoxyribonuclease V activity|endodeoxyribonuclease (pyrimidine dimer) activity Catalysis of the endonucleolytic cleavage near pyrimidine dimers to products with 5'-phosphate. GO:0018276 isopeptide cross-linking via N6-glycyl-L-lysine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018276 RESID:AA0125 The formation of an isopeptide cross-link between peptidyl-lysine and peptidyl-glycine to produce N6-glycyl-L-lysine. This is distinct from the formation of the thiolester intermediate, which occurs during ubiquitination. GO:0033891 CC-preferring endodeoxyribonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033891 EC:3.1.21.6|MetaCyc:3.1.21.6-RXN 5'-CC-3'-preferring endodeoxyribonuclease activity|Streptomyces glaucescens exocytoplasmic dodeoxyribonuclease activity|Streptomyces glaucescens exocytoplasmic endonuclease activity|Streptomyces glaucescens exocytoplasmic endodeoxyribonuclease activity Catalysis of the endonucleolytic cleavage to give 5'-phosphooligonucleotide end-products, with a preference for cleavage within the sequence CC. GO:0033890 ribonuclease D activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033890 EC:3.1.13.5|MetaCyc:3.1.13.5-RXN RNase D activity Catalysis of the exonucleolytic cleavage that removes extra residues from the 3'-terminus of tRNA to produce 5'-mononucleotides. GO:0018275 N-terminal peptidyl-cysteine acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018275 RESID:AA0043 peptidyl-cysteine N-acetylation The acetylation of the N-terminal cysteine of proteins to form the derivative N-acetyl-L-cysteine. CHEBI:58819 (R,R)-chrysanthemyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58819 CHEBI:58818 (1R,2S,5S,6S)-2-(3-carboxylatopropanoyl)-5-[(1-carboxylatovinyl)oxy]-6-hydroxycyclohex-3-ene-1-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58818 CHEBI:58817 2-(3-methylthiopropyl)malate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58817 CHEBI:58816 2-(2-methylthioethyl)malate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58816 CHEBI:58815 5-methylthio-2-oxopentanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58815 CHEBI:34848 mevastatin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_34848 CHEBI:58813 leachianone G(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58813 CHEBI:58812 sophoraflavanone B(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58812 CHEBI:19203 1H-pyrrole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_19203 CHEBI:58811 phenylglyoxylyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58811 CHEBI:58810 deoxycholoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58810 CHEBI:58809 3alpha,7alpha,12alpha-trihydroxy-5alpha-cholan-24-yl sulfate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58809 CHEBI:58808 5beta-scymnol sulfate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58808 CHEBI:58807 ascopyrone P(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58807 CHEBI:58806 ascopyrone M(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58806 CHEBI:58805 c-di-GMP(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58805 CHEBI:58804 12alpha-hydroxy-3-oxochola-4,6-dien-24-oate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58804 CHEBI:58803 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58803 CHEBI:995 cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_995 CHEBI:994 cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_994 CHEBI:58802 5-amino-2-oxopentanoic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58802 CHEBI:58801 3-hydroxycyclohexa-1,5-diene-1-carbonyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58801 CHEBI:58800 4-(L-gamma-glutamylamino)butanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58800 UBERON:0015251 modified sebaceous gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015251 UBERON:0015249 digit skin biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015249 A zone of skin that is part of a digit [Automatically generated definition]. CHEBI:19218 2',3'-cyclic pyrimidine nucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19218 CHEBI:19217 2',3'-cyclic purine nucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19217 CHEBI:83819 (25S)-3-oxocholest-4-en-26-oyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83819 CHEBI:83818 morphinane-like compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83818 CHEBI:83813 proteinogenic amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83813 CHEBI:83812 non-proteinogenic amino acid derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83812 CHEBI:83811 proteinogenic amino acid derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83811 CHEBI:10836 2',3,4,4',6'-pentahydroxychalcone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_10836 CHEBI:83828 DNA polyanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83828 CHEBI:83824 L-cysteine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83824 CHEBI:83822 non-proteinogenic L-alpha-amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83822 CHEBI:83821 amino acid derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83821 CHEBI:83820 non-proteinogenic amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83820 CHEBI:83836 UDP-beta-L-rhamnose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83836 CHEBI:83834 peptidylproline (omega=180) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83834 CHEBI:83833 peptidylproline (omega=0) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83833 UBERON:0015281 pancreas right lobe biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015281 A pancreatic lobule that is in_the_right_side_of a exocrine pancreas. UBERON:0015280 pancreas left lobe biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015280 A pancreatic lobule that is in_the_left_side_of a exocrine pancreas. GO:0033806 fluorothreonine transaldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033806 RHEA:11748|EC:2.2.1.8 fluoroacetaldehyde:L-threonine aldehydetransferase activity Catalysis of the reaction: L-threonine + fluoroacetaldehyde = acetaldehyde + 4-fluoro-L-threonine. GO:0043171 peptide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043171 peptide breakdown|peptide catabolism|peptide degradation The chemical reactions and pathways resulting in the breakdown of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. GO:0043170 macromolecule metabolic process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0043170 multicellular organismal macromolecule metabolic process|biopolymer metabolic process|organismal macromolecule metabolism|macromolecule metabolism The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. GO:0008849 enterochelin esterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008849 MetaCyc:RXN0-1661|RHEA:28018 enterobactin esterase activity Catalysis of the reaction: enterobactin + 3 H2O = 3 N-23-dihydroxybenzoyl-L-serine + 3 H+. GO:0033805 obsolete sarcosine/dimethylglycine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033805 SDMT|sarcosine dimethylglycine methyltransferase activity|sarcosine dimethylglycine N-methyltransferase activity|S-adenosyl-L-methionine:N,N-dimethylglycine N-methyltransferase activity|sarcosine/dimethylglycine N-methyltransferase activity|ApDMT OBSOLETE. Catalysis of the reactions: S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine + N,N-dimethylglycine, and S-adenosyl-L-methionine + N,N-dimethylglycine = S-adenosyl-L-homocysteine + betaine. GO:0033804 obsolete glycine/sarcosine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033804 glycine sarcosine N-methyltransferase activity|GSMT|GMT|S-adenosyl-L-methionine:sarcosine N-methyltransferase activity|glycine-sarcosine methyltransferase activity|ApGSMT|glycine/sarcosine N-methyltransferase activity OBSOLETE. Catalysis of the reactions: S-adenosyl-L-methionine + glycine = S-adenosyl-L-homocysteine + sarcosine, and S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine + N,N-dimethylglycine. GO:0043173 nucleotide salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043173 Wikipedia:Nucleotide_salvage Any process which produces a nucleotide, a compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety, from derivatives of it without de novo synthesis. GO:0008848 obsolete enterobactin synthetase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008848 enterochelin synthetase activity|nonribosomal peptide synthetase|enterobactin synthetase OBSOLETE. (Was not defined before being made obsolete). GO:0033803 kaempferol 4'-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033803 EC:2.1.1.155|KEGG_REACTION:R06807|RHEA:15105|MetaCyc:2.1.1.155-RXN F 4'-OMT|S-adenosyl-L-methionine:flavonoid 4'-O-methyltransferase activity|S-adenosyl-L-methionine:kaempferol 4'-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + kaempferol = S-adenosyl-L-homocysteine + H(+) + kaempferide. GO:0008847 Enterobacter ribonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008847 MetaCyc:3.1.27.6-RXN|EC:4.6.1.21 Enterobacter RNase activity|enterobacter ribonuclease activity Catalysis of the endonucleolytic cleavage to 3'-phosphomononucleotides and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates. GO:0043172 obsolete ferredoxin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043172 ferredoxin anabolism|ferredoxin biosynthesis|ferredoxin synthesis|ferredoxin formation OBSOLETE. The chemical reactions and pathways resulting in the formation of ferredoxin, any simple, nonenzymatic iron-sulfur protein that is characterized by having equal numbers of atoms of iron and labile sulfur. Iron and sulfur atoms are present in one or two clusters of two or four atoms of each. GO:0008846 obsolete endopeptidase La activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008846 PIM1 proteinase activity|gene lon protease activity|PIM1 protease activity|ATP-dependent serine proteinase activity|gene lon proteins|lon proteinase|endopeptidase La activity|Escherichia coli proteinase La|proteinase La|Escherichia coli serine proteinase La|protease La|serine protease La|ATP-dependent protease La activity|ATP-dependent lon proteinase OBSOLETE. Catalysis of the hydrolysis of large proteins such as globin, casein and denatured serum albumin, in presence of ATP. GO:0033802 isoliquiritigenin 2'-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033802 EC:2.1.1.154|MetaCyc:RXN-3501|RHEA:21608|KEGG_REACTION:R07242 CHMT|chalcone OMT|S-adenosyl-L-methionine:isoliquiritigenin 2'-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + isoliquiritigenin = 2'-O-methylisoliquiritigenin + S-adenosyl-L-homocysteine + H(+). GO:0008845 obsolete endonuclease VIII activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008845 endonuclease VIII activity OBSOLETE. (Was not defined before being made obsolete). GO:0033801 vitexin 2''-O-rhamnoside 7-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033801 EC:2.1.1.153|MetaCyc:RXN-4981|RHEA:11432 S-adenosyl-L-methionine:vitexin-2''-O-beta-L-rhamnoside 7-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + vitexin 2''-O-beta-L-rhamnoside = S-adenosyl-L-homocysteine + 7-O-methylvitexin 2''-O-beta-L-rhamnoside. GO:0033800 isoflavone 7-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033800 EC:2.1.1.150|MetaCyc:RXN-6241|RHEA:17933 S-adenosyl-L-methionine:hydroxyisoflavone 7-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + a 7-hydroxyisoflavone = S-adenosyl-L-homocysteine + a 7-methoxyisoflavone. GO:0008844 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008844 GO:0008843 endochitinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008843 Catalysis of the hydrolysis of nonterminal (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. Typically, endochitinases cleave randomly within the chitin chain. GO:0008842 diphosphate-purine nucleoside kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008842 MetaCyc:2.7.1.143-RXN|EC:2.7.1.143 diphosphate:purine nucleoside phosphotransferase activity|pyrophosphate-purine nucleoside kinase activity|pyrophosphate-dependent nucleoside kinase activity|diphosphate-dependent nucleoside kinase activity Catalysis of the reaction: diphosphate + a purine nucleoside = monophosphate + a purine mononucleotide. GO:0043179 rhythmic excitation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043179 Any process involved in the generation of rhythmic, synchronous excitatory synaptic inputs in a neural circuit. GO:0008841 dihydrofolate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008841 MetaCyc:DIHYDROFOLATESYNTH-RXN|EC:6.3.2.12|RHEA:23584 H(2)-folate synthetase activity|dihydrofolate synthetase-folylpolyglutamate synthetase activity|folylpoly-(gamma-glutamate) synthetase-dihydrofolate synthase activity|dihydrofolate synthetase activity|7,8-dihydropteroate:L-glutamate ligase (ADP-forming)|FHFS activity|DHFS activity|7,8-dihydropteroate:L-glutamate ligase (ADP) activity|FHFS/FPGS activity|dihydropteroate:L-glutamate ligase (ADP-forming) activity|H2-folate synthetase activity|7,8-dihydrofolate synthetase activity Catalysis of the reaction: ATP + dihydropterate + L-glutamate = ADP + phosphate + dihydrofolate. GO:0043178 alcohol binding biolink:MolecularActivity go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0043178 Interacting selectively and non-covalently with an alcohol, any of a class of alkyl compounds containing a hydroxyl group. GO:0008840 4-hydroxy-tetrahydrodipicolinate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008840 RHEA:14845|EC:4.3.3.7|KEGG_REACTION:R02292|MetaCyc:DIHYDRODIPICSYN-RXN L-aspartate-4-semialdehyde hydro-lyase (adding pyruvate and cyclizing)|L-aspartate-4-semialdehyde hydro-lyase [adding pyruvate and cyclizing; (S)-2,3-dihydropyridine-2,6-dicarboxylate-forming]|dihydrodipicolinate synthase activity|DHDPS activity|dihydrodipicolinic acid synthase activity|dihydrodipicolinate synthetase activity|dihydropicolinate synthetase activity Catalysis of the reaction: pyruvate + L-aspartate-4-semialdehyde = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O. GO:0043175 RNA polymerase core enzyme binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043175 Interacting selectively and non-covalently with an RNA polymerase core enzyme, containing a specific subunit composition defined as the core enzyme. GO:0033809 anthocyanin 6''-O-malonyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033809 MetaCyc:2.3.1.171-RXN|EC:2.3.1.171|RHEA:16025 3MaT|malonyl-coenzymeA:anthocyanidin-3-O-beta-D-glucoside 6''-O-malonyltransferase activity|malonyl-CoA:anthocyanidin-3-O-beta-D-glucoside 6''-O-malonyltransferase activity|Dv3MaT Catalysis of the reaction: malonyl-CoA + an anthocyanidin 3-O-beta-D-glucoside = CoA + an anthocyanidin 3-O-(6-O-malonyl-beta-D-glucoside). GO:0043174 nucleoside salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043174 Any process which produces a nucleotide, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose (a deoxyribonucleotide), from derivatives of it without de novo synthesis. GO:0033808 6'-deoxychalcone synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033808 EC:2.3.1.170|MetaCyc:RXN-3142|RHEA:10584 malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing, reducing) activity Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA + NADPH + H+ = 4 CoA + isoliquiritigenin + 3 CO2 + NADP+ + H2O. GO:0043177 organic acid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043177 Interacting selectively and non-covalently with an organic acid, any acidic compound containing carbon in covalent linkage. CHEBI:904 2,4-diaminopentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_904 GO:0033807 icosanoyl-CoA synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033807 MetaCyc:ICOSANOYL-COA-SYNTHASE-RXN|EC:2.3.1.119 acyl-CoA elongase activity|stearoyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing) activity|stearoyl-CoA elongase activity|C18-CoA elongase activity Catalysis of the reaction: stearoyl-CoA + malonyl-CoA + 2 NAD(P)H + 2 H+ = icosanoyl-CoA + CO2 + 2 NAD(P)+. GO:0043176 amine binding biolink:MolecularActivity go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0043176 Interacting selectively and non-covalently with any organic compound that is weakly basic in character and contains an amino or a substituted amino group. CHEBI:138625 (+)-jasmonic acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138625 CHEBI:58893 precorrin-1(8-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58893 CHEBI:58892 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58892 UBERON:0005870 olfactory pit biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005870 nasal pit An indentation of the olfactory placode which ends when the pits hollows out to form the nasopharynx[GO]. CHEBI:58891 6-(alpha-D-glucosaminyl)-1D-myo-inositol 1,2-cyclic phosphate zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58891 CHEBI:138623 O-[S-(pyrrole-2-carbonyl)pantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138623 CHEBI:58890 2,5-diamino-6-(1-D-ribitylamino)pyrimidin-4(3H)-one 5'-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58890 CHEBI:138622 O-(S-L-prolylpantetheine-4'-phosphoryl)serine zwitterionic residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138622 CHEBI:138628 2-hydroxybutanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138628 CHEBI:138627 N-[(3R)-jasmonyl]-L-isoleucinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138627 CHEBI:138626 N-[(3R)-12-hydroxyjasmonyl]-L-isoleucinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138626 UBERON:0005879 pharyngeal cleft biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005879 pharyngeal groove|branchial groove|pharyngeal groove ectoderm|Kiemenspalten|sulcus pharyngei|pharyngeal ectodermal cleft|pharyngeal slit|branchial cleft|gill cleft An external pocketing of pharyngeal ectoderm that contacts a region of endoderm (a pharyngeal pouch) and interdigitates in the anterior and posterior directions by the pharyngeal arches. CHEBI:58899 alpha-D-glucosiduronate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58899 CHEBI:58898 2-azaniumyl-4,5-dihydroxy-6-oxo-7-(phosphonatooxy)heptanoate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58898 UBERON:0005876 undifferentiated genital tubercle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005876 phallic tubercle|genital tubercle|tuberculum phallicum|tuberculum genitale|undifferentiated genital tubercle the embryonic anlage of the external genitalia, which emerges as paired swellings ventral to the cloacal membrane, is proposed to be derived from all three germ layers, and gives rise to the penis, clitoris, scrotum, labia, and foreskin CHEBI:58897 1,4-dihydroxy-2-naphthoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58897 UBERON:0005875 4th arch pharyngeal cleft biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005875 4th pharyngeal cleft|branchial groove of 4th arch|4th branchial cleft|4th pharyngeal groove|4th arch branchial groove|4th pharyngeal groove ectoderm|4th arch pharyngeal groove ectoderm A groove that is situated between the 4th and 5th pharyngeal arch. CHEBI:138621 [(3S,4R)-4-alkanoyl-5-oxooxolan-3-yl]methyl phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138621 UBERON:0005874 3rd arch pharyngeal cleft biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005874 3rd pharyngeal cleft|branchial groove of 3rd arch|3rd pharyngeal groove ectoderm|3rd branchial cleft|3rd pharyngeal groove|3rd arch branchial groove|3rd arch groove ectoderm A groove that is situated between the 3rd and 4th pharyngeal arch. CHEBI:58896 2-hydroxy carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58896 CHEBI:138620 O-[S-(D-alanyl)pantetheine-4'-phosphoryl]-L-serine zwitterionic residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138620 CHEBI:58895 2-carboxylato-4-methyl-5-[(2-phosphonatooxy)ethylidene]-2,5-dihydrothiazole(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58895 UBERON:0005873 2nd arch pharyngeal cleft biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005873 2nd pharyngeal cleft|branchial groove of 2nd arch|2nd branchial cleft|2nd pharyngeal groove|2nd arch branchial groove|2nd pharyngeal groove ectoderm|2nd arch groove ectoderm A groove that is situated between the 2nd and 3rd pharyngeal arch. CHEBI:58894 cob(II)yrinate(6-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58894 UBERON:0005872 1st arch pharyngeal cleft biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005872 1st pharyngeal groove|1st arch branchial groove|1st arch groove ectoderm|1st pharyngeal cleft|branchial groove of 1st arch|1st pharyngeal groove ectoderm|1st branchial cleft A groove that is situated between the 1st and 2nd pharyngeal arch. GO:0043182 vacuolar sequestering of sodium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043182 vacuolar sequestration of sodium ion (Na+)|vacuolar sequestering of sodium ion (Na+)|sodium ion (Na+) storage in vacuole|sequestration of sodium ion (Na+) in vacuole|sodium ion (Na+) retention in vacuole|vacuolar sodium ion (Na+) retention|vacuolar sodium ion (Na+) storage|sequestering of sodium ion (Na+) in vacuole The process of transporting sodium ions into, and confining within, a vacuole. GO:0043181 vacuolar sequestering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043181 vacuolar sequestration|sequestration in vacuole|storage in vacuole|retention in vacuole|sequestering in vacuole|vacuolar retention|vacuolar storage The process of transporting a substance into, and confining within, a vacuole. GO:0043184 vascular endothelial growth factor receptor 2 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043184 VEGF receptor 2 binding|VEGFR 2 binding|kinase domain region binding|KDR binding|Flk-1 binding Interacting selectively and non-covalently with vascular endothelial growth factor receptor 2. GO:0008859 exoribonuclease II activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008859 EC:3.1.13.1|MetaCyc:3.1.13.1-RXN ribonuclease Q|RNase II activity|ribonuclease II activity|5'-exoribonuclease activity|RNase II|BN ribonuclease activity|Escherichia coli exo-RNase II Catalysis of the reaction: RNA + H2O = 5'-phosphomononucleotides. Cleaves RNA in the 3' to 5' direction. GO:0043183 vascular endothelial growth factor receptor 1 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043183 VEGF receptor 1 binding|VEGFR 1 binding|Flt-1 binding Interacting selectively and non-covalently with vascular endothelial growth factor receptor 1. GO:0008858 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008858 CHEBI:19281 2,2'-bithiophenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19281 GO:0008857 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008857 GO:0008856 exodeoxyribonuclease X activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008856 EC:3.1.11.-|MetaCyc:3.1.22.5-RXN Escherichia coli endodeoxyribonuclease activity|deoxyribonuclease X activity|Escherichia coli endodeoxyribonuclease X activity Catalysis of the endonucleolytic cleavage of supercoiled plasma DNA to linear DNA duplexes. GO:0008855 exodeoxyribonuclease VII activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008855 EC:3.1.11.6|MetaCyc:3.1.11.6-RXN endodeoxyribonuclease VII|Escherichia coli exonuclease VII|E. coli exonuclease VII|E. coli exonuclease VII activity|exonuclease VII activity Catalysis of the exonucleolytic cleavage in either 5' to 3' or 3' to 5' direction to yield 5'-phosphomononucleotides. GO:0043180 rhythmic inhibition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043180 Any process involved in the generation of rhythmic, synchronous inhibitory synaptic inputs in a neural circuit. GO:0008854 exodeoxyribonuclease V activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008854 EC:3.1.11.5|MetaCyc:3.1.11.5-RXN Escherichia coli exonuclease V|gene recBCD enzymes|E. coli exonuclease V|gene recBC endoenzyme|RecBC deoxyribonuclease activity|E. coli exonuclease V activity|gene recBC DNase activity|exonuclease V activity Catalysis of the exonucleolytic cleavage (in the presence of ATP) in either 5' to 3' or 3' to 5' direction to yield 5'-phosphooligonucleotides. GO:0008853 exodeoxyribonuclease III activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008853 EC:3.1.11.2|MetaCyc:3.1.11.2-RXN exonuclease III activity|Escherichia coli exonuclease III|E. coli exonuclease III|endoribonuclease III|E. coli exonuclease III activity Catalysis of the degradation of double-stranded DNA. It acts progressively in a 3' to 5' direction, releasing 5'-phosphomononucleotides. GO:0008852 exodeoxyribonuclease I activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008852 EC:3.1.11.1|MetaCyc:3.1.11.1-RXN exonuclease I activity|Escherichia coli exonuclease I|E. coli exonuclease I|E. coli exonuclease I activity Catalysis of the degradation of single-stranded DNA. It acts progressively in a 3' to 5' direction, releasing 5'-phosphomononucleotides. GO:0043189 H4/H2A histone acetyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043189 H4/H2A HAT complex A multisubunit complex that catalyzes the acetylation of histones H4 and H2A. GO:0008851 ethanolamine ammonia-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008851 MetaCyc:ETHAMLY-RXN|RHEA:15313|EC:4.3.1.7 ethanolamine deaminase activity|ethanolamine ammonia-lyase (acetaldehyde-forming) activity Catalysis of the reaction: ethanolamine = acetaldehyde + NH3. CHEBI:44247 (15Z)-tetracosenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_44247 GO:0008850 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008850 CHEBI:44245 menaquinone-7 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_44245 GO:0043186 P granule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043186 nuage|polar granule|germline granule A small cytoplasmic, non-membranous RNA/protein complex aggregate in the primordial germ cells of many higher eukaryotes. GO:0043185 vascular endothelial growth factor receptor 3 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043185 VEGFR 3 binding|fms-like-tyrosine kinase (Flt)-4 binding|VEGF receptor 3 binding Interacting selectively and non-covalently with vascular endothelial growth factor receptor 3. GO:0043188 cell septum edging biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043188 The cell wall material that surrounds the septum in fungal cells. CHEBI:915 2,4-dihydroxyhept-2-enedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_915 GO:0043187 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043187 CHEBI:138636 2-hydroxy-3-methyldodecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138636 CHEBI:58882 phosphinothricin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58882 CHEBI:138635 (R)-2-hydroxyhexadecanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138635 CHEBI:58881 N-acetyl-D-hexosamine 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58881 CHEBI:138634 3-methylnonanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138634 CHEBI:138633 2-hydroxy-3-methylnonanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138633 CHEBI:2229 6-phospho-2-dehydro-D-gluconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_2229 CHEBI:138637 3-methyldodecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138637 UBERON:0005868 maxillary prominence biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005868 maxillary process|embryonic maxillary process|maxillary process of embryo|prominentia maxilaris the paired dorsal prominences formed by bifurcation of the first pharyngeal arches in the embryo that unite with the ipsilateral medial nasal process to form the upper jaw UBERON:0005867 mandibular prominence biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005867 mandibular process|prominentia mandibularis|mandibular swelling the paired ventral prominences formed by bifurcation of the first pharyngeal arches in the embryo; the two prominences unite ventrally and fuse to form the mandible and lower lip UBERON:0005866 pre-cartilage condensation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005866 pre-chondrogenic condensation|precartilagenous condensation|precartilage condensation|prechondrogenic condensation A delimited region of dense mesenchyme within looser mesenchyme whose cells are committed to become chondroblasts. UBERON:0005865 pre-muscle condensation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005865 pre muscle mass|premuscle mass CHEBI:58887 1D-myo-inositol 2-(L-cysteiniumylamino)-2-deoxy-alpha-D-glucopyranoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58887 CHEBI:138632 2-hydroxy-3-methylundecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138632 CHEBI:58886 1D-myo-inositol 2-ammonio-2-deoxy-alpha-D-glucopyranoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58886 CHEBI:138631 heptadecanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138631 UBERON:0005863 cartilaginous condensation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005863 cartilagenous condensation|cartilage condensation|chondrogenic condensation Cell condensation that is an aggregation of mesenchymal cells that are committed to differentiate into chondroblasts and chondrocytes. CHEBI:58885 UDP-alpha-D-glucose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58885 CHEBI:138630 2-hydroxyhexanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138630 CHEBI:58884 (2R)-homocitrate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58884 CHEBI:58883 flavonolate 7-O-beta-D-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58883 CHEBI:2220 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_2220 GO:0008828 dATP pyrophosphohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008828 MetaCyc:RXN0-384|Reactome:R-HSA-2395872|Reactome:R-HSA-2395818|EC:3.6.1.56|RHEA:31583 2-hydroxy-ATP pyrophosphatase activity|2-hydroxy-(deoxy)adenosine-triphosphate pyrophosphatase activity|2-hydroxy-adenosine triphosphate pyrophosphatase activity|2-hydroxy-(d)ATP pyrophosphatase activity Catalysis of the reaction: deoxy-ATP + H2O = dAMP + diphosphate. GO:0043193 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043193 CHEBI:44230 6-(alpha-D-glucosaminyl)-1D-myo-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_44230 GO:0008827 cytochrome o ubiquinol oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008827 EC:1.10.3.- Catalysis of the reaction: ubiquinol + O2 = ubiquinone + 2 H2O; cytochrome O is the electron acceptor. GO:0043192 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043192 GO:0008826 cysteine sulfinate desulfinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008826 RHEA:28278|MetaCyc:RXN0-279|EC:4.4.1.- cysteine sulphinate desulphinase activity Catalysis of the reaction: 3-sulfinoalanine = L-alanine + sulfite. GO:0043195 terminal bouton biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043195 NIF_Subcellular:sao187426937 presynaptic bouton|synaptic bouton|bouton|terminal button Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it. CHEBI:20265 lanostane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_20265 GO:0008825 cyclopropane-fatty-acyl-phospholipid synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008825 EC:2.1.1.79|RHEA:11988|MetaCyc:2.1.1.79-RXN cyclopropane fatty acid synthetase activity|cyclopropane synthase activity|unsaturated-phospholipid methyltransferase activity|CFA synthase activity|cyclopropane fatty acid synthase activity|S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (cyclizing)|cyclopropane synthetase activity Catalysis of the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid. GO:0043194 axon initial segment biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043194 NIF_Subcellular:sao256000789 initial segment Portion of the axon proximal to the neuronal cell body, at the level of the axon hillock. The action potentials that propagate along the axon are generated at the level of this initial segment. GO:0008824 cyanate hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008824 UM-BBD_reactionID:r0608|MetaCyc:R524-RXN|RHEA:11120|EC:4.2.1.104 cyanate lyase activity|carbamate hydro-lyase activity|cyanate hydrolase activity|cyanate aminohydrolase activity|cyanate C-N-lyase activity|cyanase activity Catalysis of the reaction: cyanate + H2O = carbamate. GO:0008823 cupric reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008823 MetaCyc:R170-RXN|EC:1.16.1.- Catalysis of the reaction: Cu+ + NAD+ + H+ = Cu2+ + NADH. GO:0008822 obsolete crotonobetaine/carnitine-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008822 crotonobetaine/carnitine-CoA ligase activity OBSOLETE. (Was not defined before being made obsolete). GO:0043191 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043191 GO:0008821 crossover junction endodeoxyribonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008821 EC:3.1.22.4|MetaCyc:3.1.22.4-RXN Holliday junction-cleaving endonuclease activity|endo X3|Hje endonuclease activity|SpCCe1 holliday junction resolvase|crossover junction endoribonuclease activity|SpCCe1 Holliday junction resolvase activity|endonuclease RuvC activity|Holliday junction-resolving endoribonuclease activity|RusA endonuclease activity|RuvC endonuclease activity|RusA Holliday junction resolvase activity|Endo X3 activity|endonuclease VII activity|endonuclease X3 activity|cruciform-cutting endonuclease activity|Holliday junction nuclease activity|endodeoxyribonuclease RUS activity|RusA holliday junction resolvase|Holliday junction endonuclease CCE1 activity|Holliday junction resolvase activity|resolving enzyme CCE1 activity Catalysis of the endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction). GO:0043190 ATP-binding cassette (ABC) transporter complex biolink:CellularComponent go-plus goslim_pir|goslim_metagenomics http://purl.obolibrary.org/obo/GO_0043190 ABC-type efflux permease complex|mating pheromone exporter|ABC-type efflux porter complex|ABC-type uptake permease complex A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter. GO:0008820 cobinamide phosphate guanylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008820 RHEA:22712|KEGG_REACTION:R05222|EC:2.7.7.62|MetaCyc:COBINPGUANYLYLTRANS-RXN CobU|GTP:adenosylcobinamide-phosphate guanylyltransferase activity|AdoCbi kinase/AdoCbi-phosphate guanylyltransferase|adenosylcobinamide-phosphate guanylyltransferase activity|GTP:cobinamide phosphate guanylyltransferase activity|adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase Catalysis of the reaction: adenosylcobinamide phosphate + GTP + 2 H(+) = adenosylcobinamide-GDP + diphosphate. CHEBI:138609 short-chain (R)-3-hydroxy fatty acyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138609 CHEBI:44236 (S)-NADHX biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_44236 CHEBI:138608 (S)-3-hydroxypentanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138608 GO:0043197 dendritic spine biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0043197 NIF_Subcellular:sao1799103720|Wikipedia:Dendritic_spine sessile dendritic spine|dendrite spine|branched dendritic spine|mushroom dendritic spine|stubby dendritic spine|thin dendritic spine A small, membranous protrusion from a dendrite that forms a postsynaptic compartment, typically receiving input from a single presynapse. They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable:they can be thin, stubby, mushroom, or branched, with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity. GO:0043196 varicosity biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043196 Non-terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. GO:0043199 sulfate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043199 Interacting selectively and non-covalently with sulfate, SO4(2-), a negatively charged small molecule. GO:0043198 dendritic shaft biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043198 NIF_Subcellular:sao2034472720 trunk Cylindric portion of the dendrite, directly stemming from the perikaryon, and carrying the dendritic spines. CHEBI:58871 3,3'-biflaviolin 2,2'-diolate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58871 CHEBI:138603 (4-alkanoyl-5-oxo-2,5-dihydrofuran-3-yl)methyl phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138603 CHEBI:58870 beta-D-fructofuranosyl alpha-D-mannopyranoside 6(F)-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58870 CHEBI:138600 4,4'-diapolycopen-4-oate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138600 CHEBI:920 2,4-dinitrotoluene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_920 CHEBI:138607 (S)-3-hydroxypentanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138607 CHEBI:138605 [(3S,4R)-4-(6-methylheptanoyl)-5-oxooxolan-3-yl]methyl phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138605 CHEBI:138604 [4-(6-methylheptanoyl)-5-oxo-2,5-dihydrofuran-3-yl]methyl phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138604 CHEBI:58879 N-acetylphosphinothricin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58879 CHEBI:58878 2-oxo-1,2-dihydroquinoline-4-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58878 UBERON:0005856 developing mesenchymal condensation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005856 mesenchyme condensation A delimited region of dense mesenchyme within looser mesenchyme. CHEBI:58877 glycochenodeoxycholate 7-sulfate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58877 CHEBI:58876 murideoxycholate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58876 CHEBI:58875 hyodeoxycholate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58875 CHEBI:58874 taurohyocholate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58874 GO:0008829 dCTP deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008829 EC:3.5.4.13|MetaCyc:DCTP-DEAM-RXN|RHEA:22680|Reactome:R-HSA-180632 5-methyl-dCTP deaminase activity|deoxycytidine triphosphate deaminase activity|dCTP aminohydrolase activity Catalysis of the reaction: dCTP + H2O = dUTP + NH3. CHEBI:58872 3,8'-biflaviolin 2,2'-diolate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58872 GO:0008839 4-hydroxy-tetrahydrodipicolinate reductase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008839 MetaCyc:DIHYDROPICRED-RXN|EC:1.17.1.8 dihydrodipicolinic acid reductase activity|2,3,4,5-tetrahydrodipicolinate:NAD(P)+ oxidoreductase activity|dihydrodipicolinate reductase activity Catalysis of the reaction: (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD(P)+ + H2O = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+. GO:0008838 diaminopropionate ammonia-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008838 RHEA:22084|MetaCyc:4.3.1.15-RXN|EC:4.3.1.15 2,3-diaminopropionate ammonia-lyase activity|alpha,beta-diaminopropionate ammonia-lyase activity|diaminopropionatase activity|2,3-diaminopropionate ammonia-lyase (adding H2O; pyruvate-forming) Catalysis of the reaction: 2,3-diaminopropionate + H2O = pyruvate + 2 NH3. GO:0008837 diaminopimelate epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008837 EC:5.1.1.7|RHEA:15393|MetaCyc:DIAMINOPIMEPIM-RXN|KEGG_REACTION:R02735 LL-2,6-diaminoheptanedioate 2-epimerase activity Catalysis of the reaction: LL-2,6-diaminopimelate = meso-2,6-diaminopimelate. GO:0008836 diaminopimelate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008836 KEGG_REACTION:R00451|RHEA:15101|MetaCyc:DIAMINOPIMDECARB-RXN|EC:4.1.1.20 meso-2,6-diaminoheptanedioate carboxy-lyase (L-lysine-forming)|diaminopimelic acid decarboxylase activity|meso-2,6-diaminoheptanedioate carboxy-lyase activity|DAP-decarboxylase activity|DAP decarboxylase activity|meso-diaminopimelate decarboxylase activity Catalysis of the reaction: meso-2,6-diaminopimelate + H(+) = L-lysine + CO(2). GO:0008835 diaminohydroxyphosphoribosylaminopyrimidine deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008835 MetaCyc:RIBOFLAVINSYNDEAM-RXN|RHEA:21868|KEGG_REACTION:R03459|EC:3.5.4.26 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine 2-aminohydrolase activity|2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate deaminase activity|2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 2-aminohydrolase activity Catalysis of the reaction: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H(2)O + H(+) = 5-amino-6-(5-phosphoribosylamino)uracil + NH(4)(+). UBERON:0005838 fasciculus of brain biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005838 brain fasciculus A fascicle that is part of a brain. GO:0008834 di-trans,poly-cis-decaprenylcistransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008834 RHEA:27551|MetaCyc:RXN-8999|EC:2.5.1.31 undecaprenyl pyrophosphate synthase activity|undecaprenyl diphosphate synthase activity|bactoprenyl-diphosphate synthase activity|UPP synthetase activity|undecaprenyl-diphosphate synthase activity|undecaprenyl diphosphate synthetase activity|undecaprenyl pyrophosphate synthetase activity|di-trans,poly-cis-undecaprenyl-diphosphate synthase activity|di-trans,poly-cis-decaprenyl-diphosphate:isopentenyl-diphosphate undecaprenylcistransferase activity Catalysis of the reaction: di-trans-poly-cis-decaprenyl diphosphate + isopentenyl diphosphate = diphosphate + di-trans-poly-cis-undecaprenyl diphosphate. GO:0008833 deoxyribonuclease IV (phage-T4-induced) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008833 MetaCyc:3.1.21.2-RXN|EC:3.1.21.2 endonuclease IV activity|Escherichia coli endonuclease II|deoxriboendonuclease activity|endonuclease II|deoxyribonuclease IV (phage T4-induced) activity|endodeoxyribonuclease IV (phage T(4)-induced) activity|redoxyendonuclease activity|E. coli endonuclease IV|DNA-adenine-transferase activity|endodeoxyribonuclease IV (phage T4-induced) activity Catalysis of the endonucleolytic cleavage to 5'-phosphooligonucleotide end-products. UBERON:0005837 fasciculus of spinal cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005837 spinal cord fasciculus A fascicle that is part of a spinal cord. GO:0008832 dGTPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008832 EC:3.1.5.1|RHEA:15193|MetaCyc:DGTPTRIPHYDRO-RXN|KEGG_REACTION:R01856 deoxy-GTPase activity|deoxyguanosine triphosphatase activity|deoxyguanosinetriphosphate triphosphohydrolase activity|deoxyguanosine 5-triphosphate triphosphohydrolase activity|dGTP triphosphohydrolase activity|deoxyguanosine triphosphate triphosphohydrolase activity Catalysis of the reaction: dGTP + H(2)O = 2'-deoxyguanosine + 2 H(+) + triphosphate. CHEBI:58869 N-(3-ammoniopropyl)-4-ammoniobutanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58869 GO:0008831 dTDP-4-dehydrorhamnose reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008831 EC:1.1.1.133|MetaCyc:DTDPDEHYRHAMREDUCT-RXN|KEGG_REACTION:R02777|RHEA:21796 dTDP-6-deoxy-L-mannose dehydrogenase activity|thymidine diphospho-4-ketorhamnose reductase activity|reductase, thymidine diphospho-4-ketorhamnose|dTDP-4-keto-L-rhamnose reductase activity|TDP-4-keto-rhamnose reductase activity|dTDP-4-ketorhamnose reductase activity|dTDP-6-deoxy-L-mannose:NADP+ 4-oxidoreductase activity Catalysis of the reaction: dTDP-6-deoxy-L-mannose + NADP(+) = dTDP-4-dehydro-6-deoxy-L-mannose + H(+) + NADPH. GO:0008830 dTDP-4-dehydrorhamnose 3,5-epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008830 MetaCyc:DTDPDEHYDRHAMEPIM-RXN|RHEA:16969|EC:5.1.3.13|KEGG_REACTION:R06514 dTDP-4-keto-6-deoxyglucose 3,5-epimerase activity|dTDP-4-dehydro-6-deoxy-D-glucose 3,5-epimerase activity|TDP-4-ketorhamnose 3,5-epimerase activity|TDP-4-keto-L-rhamnose-3,5-epimerase activity|thymidine diphospho-4-ketorhamnose 3,5-epimerase activity Catalysis of the reaction: dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-L-mannose. CHEBI:2208 purine-6-thiol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_2208 CHEBI:138619 D-alanyl-AMP zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138619 CHEBI:58860 hydroxypyruvaldehyde phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58860 CHEBI:138611 O-[S-(isoheptanoyl)pantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138611 CHEBI:58868 3,7-dideoxy-D-threo-hepto-2,6-diuolosonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58868 UBERON:0005845 caudal segment of spinal cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005845 segmenta coccygea medullae spinalis [1-3]|pars coccygea medullae spinalis|segmenta coccygea|coccygeal segment of spinal cord|coccygeal segments of spinal cord [1-3] A spinal cord segment that adjacent_to a caudal region. UBERON:0005844 spinal cord segment biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005844 spinal neuromeres|axial regional part of spinal cord|segment of spinal cord|axial part of spinal cord CHEBI:58866 (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58866 CHEBI:58865 N-carbamoyl-L-alpha-amino acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58865 CHEBI:138610 O-[S-(2E)-isoheptenoylpantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138610 CHEBI:58864 dehypoxanthine futalosinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58864 CHEBI:58863 futalosinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58863 CHEBI:58862 N(2)-(3-carboxylatopropionyl)-L-citrullinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58862 CHEBI:19298 2,3,5-trichloro-cis,cis-muconate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_19298 CHEBI:58861 1-deoxy-D-threo-hexo-2,5-diulose 6-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58861 GO:0008806 carboxymethylenebutenolidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008806 MetaCyc:CARBOXYMETHYLENEBUTENOLIDASE-RXN|UM-BBD_enzymeID:e0066|EC:3.1.1.45|RHEA:12372 carboxymethylene butenolide hydrolase activity|dienelactone hydrolase activity|4-carboxymethylenebut-2-en-4-olide lactonohydrolase activity|maleylacetate enol-lactonase activity Catalysis of the reaction: 4-carboxymethylenebut-2-en-4-olide + H2O = 4 oxohex-2-enedioate. CHEBI:19252 2'-deoxyribonucleoside 3'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19252 GO:0008805 carbon-monoxide oxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008805 UM-BBD_reactionID:r0650|Wikipedia:Carbon-monoxide_dehydrogenase_(cytochrome_b-561)|MetaCyc:1.2.2.4-RXN|RHEA:13981|EC:1.2.2.4 carbon monoxide:methylene blue oxidoreductase activity|carbon monoxide,water:cytochrome b-561 oxidoreductase activity|carbon monoxide oxygenase activity|carbon-monoxide dehydrogenase (cytochrome b-561)|carbon monoxide oxygenase (cytochrome b-561) activity|cytochrome b561|carbon monoxide oxidase activity Catalysis of the reaction: CO + H2O + ferrocytochrome b-561 = CO2 + 2 H+ + 2 ferricytochrome b-561. GO:0008804 carbamate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008804 EC:2.7.2.2|RHEA:10152|MetaCyc:CARBAMATE-KINASE-RXN carbamoyl phosphokinase activity|carbamyl phosphokinase activity|CKase activity|ATP:carbamate phosphotransferase activity Catalysis of the reaction: ATP + NH3 + CO2 = ADP + carbamoyl phosphate. GO:0008803 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008803 MetaCyc:3.6.1.41-RXN|KEGG_REACTION:R00125|EC:3.6.1.41|RHEA:24252 bis(5'-adenosyl) tetraphosphatase activity|diadenosine polyphosphate hydrolase activity|diadenosinetetraphosphatase (symmetrical) activity|symmetrical diadenosine tetraphosphate hydrolase activity|diadenosine tetraphosphate hydrolase activity|Ap4A hydrolase activity|adenosine tetraphosphate phosphodiesterase activity|diadenosine 5',5'''-P(1),P(4)-tetraphosphate pyrophosphohydrolase activity|dinucleosidetetraphosphate (symmetrical)|dinucleosidetetraphosphatase (symmetrical) activity|diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase activity|1-P,4-P-bis(5'-nucleosyl)-tetraphosphate nucleosidebisphosphohydrolase activity|diadenosine 5',5'''-P1,P4-tetraphosphatase activity|diadenosine tetraphosphatase (symmetrical)|Ap(4)A hydrolase activity|P1,P4-bis(5'-nucleosyl)-tetraphosphate nucleosidebisphosphohydrolase activity Catalysis of the reaction: P(1),P(4)-bis(5'-adenosyl) tetraphosphate + H(2)O = 2 ADP + 2 H(+). GO:0008802 betaine-aldehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008802 Reactome:R-HSA-6797955|MetaCyc:BADH-RXN|RHEA:15305|EC:1.2.1.8 betaine-aldehyde:NAD+ oxidoreductase activity|betaine aldehyde oxidase activity|BetB|betaine aldehyde dehydrogenase activity|BADH activity Catalysis of the reaction: betaine aldehyde + NAD+ + H2O = betaine + NADH + H+. GO:0008801 beta-phosphoglucomutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008801 KEGG_REACTION:R02728|MetaCyc:BETA-PHOSPHOGLUCOMUTASE-RXN|RHEA:20113|EC:5.4.2.6 beta-D-glucose 1,6-phosphomutase activity Catalysis of the reaction: beta-D-glucose 1-phosphate = beta-D-glucose 6-phosphate. CHEBI:58859 2-amino-2,3,7-trideoxy-D-lyxo-hept-6-ulosonic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58859 GO:0008800 beta-lactamase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008800 MetaCyc:BETA-LACTAMASE-RXN|RHEA:20401|EC:3.5.2.6 penicillinase I, II|neutrapen|exopenicillinase activity|cephalosporin-beta-lactamase activity|ampicillinase activity|beta-lactamase I-III|beta-lactam hydrolase activity|beta-lactamase A, B, C|beta-lactamase AME I|penicillin beta-lactamase activity|penicillin amido-beta-lactamhydrolase activity Catalysis of the reaction: a beta-lactam + H2O = a substituted beta-amino acid. CHEBI:58858 N-(3-acetamidopropyl)-4-ammoniobutanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58858 UBERON:0015238 pineal complex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015238 A cluster in the epithalamus that consists of the pineal body and any associated structures, such as the parapineal gland or the parietal organ. The complex is poorly developed in mammals. CHEBI:44215 NAD zwitterion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_44215 UBERON:0015234 nucleus of ventral thalamus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015234 ventral thalamic nucleus A nucleus of brain that is part of a ventral thalamus. UBERON:0015233 nucleus of dorsal thalamus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015233 nucleus of thalamus proper|dorsal thalamic nucleus A nucleus of brain that is part of a dorsal thalamus. CHEBI:2255 7beta-aminocephalosporanic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_2255 CHEBI:44219 (4-amino-2-methylpyrimidin-5-yl)methyl dihydrogen phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_44219 CHEBI:58856 2,3-trans-enoyl CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58856 CHEBI:58855 secondary aliphatic ammonium ion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58855 CHEBI:58854 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58854 CHEBI:58853 (2S,3S)-2-methylcitrate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58853 CHEBI:58852 5-deoxy-D-glucuronate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58852 CHEBI:2251 7,8-dihydromethanopterin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_2251 GO:0008809 carnitine racemase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008809 MetaCyc:CARNRACE-RXN Catalysis of the reaction: D-carnitine = L-carnitine. GO:0008808 cardiolipin synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008808 MetaCyc:CARDIOLIPSYN-RXN|RHEA:31451|EC:2.7.8.- cardiolipin synthetase activity|cardiolipin synthetase 2 activity|diphosphatidylglycerol synthase activity|cardiolipin synthase 2 activity Catalysis of the reaction: phosphatidylglycerol + phosphatidylglycerol = diphosphatidylglycerol (cardiolipin) + glycerol. CHEBI:58851 2-methyl-3-oxosuccinate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58851 GO:0008807 carboxyvinyl-carboxyphosphonate phosphorylmutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008807 MetaCyc:2.7.8.23-RXN|EC:2.7.8.23|RHEA:14045 CPEP phosphonomutase activity|1-carboxyvinyl carboxyphosphonate phosphorylmutase (decarboxylating)|carboxyphosphonoenolpyruvate phosphonomutase activity Catalysis of the reaction: 1-carboxyvinyl carboxyphosphonate = 3-(hydrohydroxyphosphoryl)pyruvate + CO2. CHEBI:58850 (3S)-3-hydroxy-L-asparagine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58850 GO:0008817 cob(I)yrinic acid a,c-diamide adenosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008817 Reactome:R-HSA-3322125|Reactome:R-HSA-3159253|EC:2.5.1.17|MetaCyc:COBALADENOSYLTRANS-RXN|RHEA:14725 ATP:corrinoid adenosyltransferase activity|vitamin B12s adenosyltransferase activity|CobA|ATP:cob(I)yrinic acid-a,c-diamide cobeta-adenosyltransferase activity|ATP:cob(I)alamin cobeta-adenosyltransferase activity|aquocob(I)alamin vitamin B12s adenosyltransferase activity|cob(I)alamin adenosyltransferase activity|aquacob(I)alamin adenosyltransferase activity|ATP:cob(I)alamin Co-beta-adenosyltransferase activity Catalysis of the reaction: ATP + cob(I)alamin + H2O = phosphate + diphosphate + adenosylcobalamin. GO:0008816 citryl-CoA lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008816 MetaCyc:CITRYLY-RXN|RHEA:20812|EC:4.1.3.34 (3S)-citryl-CoA oxaloacetate-lyase (acetyl-CoA-forming)|(3S)-citryl-CoA oxaloacetate-lyase activity Catalysis of the reaction: (3S)-citryl-CoA = acetyl-CoA + oxaloacetate. GO:0008815 citrate (pro-3S)-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008815 RHEA:10760|KEGG_REACTION:R00362|EC:4.1.3.6|MetaCyc:CITLY-RXN citrate oxaloacetate-lyase [(pro-3S)-CH2COO-->acetate]|citrase activity|citrate aldolase activity|citrate oxaloacetate-lyase activity|citridesmolase activity|citrate lyase activity|citratase activity|citric aldolase activity|citritase activity Catalysis of the reaction: citrate = acetate + oxaloacetate. GO:0008814 citrate CoA-transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008814 RHEA:19405|EC:2.8.3.10|MetaCyc:CITTRANS-RXN acetyl-CoA:citrate CoA-transferase activity Catalysis of the reaction: acetyl-CoA + citrate = acetate + (3S)-citryl-CoA. GO:0008813 chorismate lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008813 EC:4.1.3.40|MetaCyc:CHORPYRLY-RXN|KEGG_REACTION:R01302|RHEA:16505 CL|UbiC|CPL|chorismate pyruvate lyase activity|chorismate pyruvate-lyase (4-hydroxybenzoate-forming) activity|4-hydroxybenzoate synthetase activity Catalysis of the reaction: chorismate = 4-hydroxybenzoate + pyruvate. GO:0008812 choline dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008812 KEGG_REACTION:R01025|MetaCyc:CHD-RXN|RHEA:17433|EC:1.1.99.1|Reactome:R-HSA-6797961 choline-cytochrome c reductase activity|choline:(acceptor) 1-oxidoreductase activity|choline:(acceptor) oxidoreductase activity|choline:acceptor 1-oxidoreductase activity|choline oxidase activity Catalysis of the reaction: A + choline = AH(2) + betaine aldehyde. CHEBI:58849 N,N-dihydroxypentahomomethioninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58849 GO:0008811 chloramphenicol O-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008811 KEGG_REACTION:R03065|RHEA:18421|EC:2.3.1.28|MetaCyc:CHLORAMPHENICOL-O-ACETYLTRANSFERASE-RXN chloramphenicol transacetylase activity|chloramphenicol acetylase activity|CAT II|acetyl-CoA:chloramphenicol 3-O-acetyltransferase activity|CAT III|CAT I|chloramphenicol acetyltransferase activity Catalysis of the reaction: chloramphenicol + acetyl-CoA = chloramphenicol 3-acetate + CoA. CHEBI:58848 N,N-dihydroxytetrahomomethioninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58848 GO:0008810 cellulase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008810 EC:3.2.1.4|MetaCyc:RXN-2043 celludextrinase activity|endoglucanase D|celluase A|alkali cellulase activity|carboxymethyl cellulase activity|9.5 cellulase activity|avicelase activity|cellulase A 3|endo-1,4-beta-D-glucanase activity|1,4-(1,3;1,4)-beta-D-glucan 4-glucanohydrolase activity|cellulosin AP|beta-1,4-endoglucan hydrolase activity|pancellase SS|endoglucanase activity|endo-1,4-beta-D-glucanohydrolase activity|beta-1,4-glucanase activity|endo-1,4-beta-glucanase activity Catalysis of the endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans. CHEBI:58847 N,N-dihydroxytrihomomethioninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58847 UBERON:0015228 circulatory organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015228 circulatory vessel|heart or heart like organ|heart|cardiac pump|cardiac structure A hollow, muscular organ, which, by contracting rhythmically, contributes to the circulation of lymph, blood or analogs. Examples: a chambered vertebrate heart; the tubular peristaltic heart of ascidians; the dorsal vessel of an insect; the lymoh heart of a reptile. UBERON:0015225 atrial foramen intermedium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015225 ostium intermedium|interatrial ostium intermedium A anatomical conduit that is part of a atrial septum intermedium. UBERON:0015224 interventricular foramen intermedium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015224 interventricular ostium intermedium A anatomical conduit that is part of a ventricular septum intermedium. CHEBI:34892 nocodazole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_34892 CHEBI:44209 methylamino group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_44209 CHEBI:19239 2'-deoxyadenosine phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19239 CHEBI:58846 N,N-dihydroxydihomomethioninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58846 CHEBI:19237 2'-deoxyadenosine 5'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19237 CHEBI:58845 N,N-dihydroxyhexahomomethioninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58845 CHEBI:58844 N-hydroxyhexahomomethioninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58844 CHEBI:58843 N-hydroxypentahomomethioninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58843 CHEBI:2260 7-deoxyloganic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_2260 CHEBI:58842 N-hydroxytetrahomomethioninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58842 CHEBI:58841 N-hydroxytrihomomethioninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58841 CHEBI:58840 N-hydroxydihomomethioninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58840 GO:0008819 cobinamide kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008819 Catalysis of the reaction: cobinamide + ATP = cobinamide phosphate + ADP. This reaction is the phosphorylation of the hydroxyl group of the 1-amino-2-propanol residue of cobinamide, in the presence of ATP, to form cobinamide phosphate. OBA:0003797 axon size biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0003797 size of axon The size of a axon. GO:0008818 cobalamin 5'-phosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008818 MetaCyc:COBALAMIN5PSYN-RXN|RHEA:23560 Catalysis of the reaction: adenosylcobinamide-GDP + alpha-ribazole-5'-phosphate = adenosylcobalamin-5'-phosphate + GMP. CHEBI:19274 2'-deoxymugineic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19274 CHEBI:58839 N(6)-dihydrolipoyl-L-lysinium(1+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58839 CHEBI:58838 CDP-2,3-bis-O-(geranylgeranyl)-sn-glycerol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58838 CHEBI:58837 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58837 CHEBI:58836 hexahomomethionine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58836 UBERON:0015212 lateral structure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015212 Any structure that is placed on one side of the left-right axis of a bilaterian. UBERON:0015214 arcuate ligament biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015214 A ligament that is part of a diaphragm. UBERON:0005893 leg bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005893 A bone that is part of the region of the hindlimb that includes the zeugopod and stylopod. Examples: patella, femur, tibia. Counter-examples: any pes phalanx UBERON:0005891 coelomic epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005891 germinal epithelium of Waldeyer|celomic epithelium The epithelial lining of the surface of the coelom. CHEBI:34862 N-(30-(9Z,12Z-octadecadienoyloxy)-tricontanoyl)-sphing-4-enine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_34862 CHEBI:58835 pentahomomethionine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58835 CHEBI:58834 tetrahomomethionine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58834 UBERON:0005899 pes bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005899 bone of pedal skeleton|bone of foor proper or tarsal skeleton|bone of foot|foot bone|bone of pes A bone that is part of the pes skeleton CHEBI:58833 trihomomethionine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58833 CHEBI:58832 dihomomethionine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58832 UBERON:0005897 manus bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005897 forelimb autopod bone|bone of hand|bone of pectoral limb autopodium|hand bone|bone of hand skeleton|bone of manus|forelimb autopodium bone|bone of pectoral limb autopod A bone that is part of the manus skeleton. Note that this includes the carpal bones. CHEBI:58831 iminoaspartate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58831 CHEBI:58830 (2S)-2-hydroxy-3-oxobutyl phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58830 UBERON:0005895 insect leg biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005895 imaginal disc-derived leg The walking appendages of each segment of the ventral adult external thorax[FBbt]. A leg derived from an imaginal disc[GO]. CHEBI:19260 2'-deoxyribonucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19260 CHEBI:58828 5-(methylsulfanyl)-2,3-dioxopentyl phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58828 CHEBI:58827 precorrin-2(7-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58827 CHEBI:58826 N-acetyl-beta-D-glucosamine 6-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58826 PO:0005702 aerenchyma biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0005702 portion of aerenchyma tissue (related)|通気組織 (Japanese, exact)|aerénquima (Spanish, exact) A portion of parenchyma tissue containing particularly large intercellular spaces of schizogenous or lysigenous origin. CHEBI:58825 (R)-beta-alanopine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58825 CHEBI:978 2-(1-hydroxyethyl)thiamine diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_978 UBERON:0005882 neural tube alar plate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005882 alar plate|alar plate of neural tube|sensory part of neural tube|alar lamina|lamina alaris|dorsal part of neural tube|lamina dorsolateralis The mantle layer of the neural tube that lies dorsal to the sulcus limitans and contains primarily sensory neurons and interneurons involved in communication of sensory impulses. NCBITaxon:7041 Coleoptera organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_7041 beetles|beetles UBERON:0005881 autopodial extension biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005881 digit or predigit|limb outgrowth A subdivision of the autopod that corresponds to one or more bones arranged in series branching from the main limb axis. CHEBI:2247 7,8-diaminononanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_2247 CHEBI:58824 sulfonatoacetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58824 CHEBI:58822 tuberculosinyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58822 CHEBI:19257 2'-deoxyribonucleoside monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19257 CHEBI:58821 terpentedienyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58821 CHEBI:58820 lavandulyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58820 CHEBI:19255 pyrimidine 2'-deoxyribonucleoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19255 UBERON:0005884 hyoid arch skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005884 hyoid arch skeleton|hyal@fr|pharyngeal arch 2 skeleton|hyoid bars|visceral arch 2|hyocïde@fr|hyoid arch A subdivision of skeleton that supports pharyngeal arch 2. CHEBI:19254 purine 2'-deoxyribonucleoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_19254 GO:0018371 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018371 GO:0018370 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018370 GO:0043333 2-octaprenyl-6-methoxy-1,4-benzoquinone methylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043333 EC:2.1.1.201|MetaCyc:2-OCTAPRENYL-METHOXY-BENZOQ-METH-RXN 2-octaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity Catalysis of the reaction: 2-octaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine. GO:0043332 mating projection tip biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043332 shmoo tip|conjugation tube tip The apex of the mating projection in unicellular fungi exposed to mating pheromone; site of polarized growth. GO:0043335 protein unfolding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043335 The process of assisting in the disassembly of non-covalent linkages in a protein or protein aggregate, often where the proteins are in a non-functional or denatured state. GO:0043334 2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043334 2-hexaprenyl-6-methoxy-1,4-benzoquinone methylase activity Catalysis of the reaction: 2-hexaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-hexaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine. GO:0043331 response to dsRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043331 response to double-stranded RNA Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded RNA stimulus. GO:0043330 response to exogenous dsRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043330 response to viral dsRNA|response to exogenous double-stranded RNA Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus. CHEBI:138229 N-acetyl-alpha-D-muramic acid 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138229 CHEBI:138228 beta-heptaprene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138228 CHEBI:138227 beta-hexaprene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138227 CHEBI:138226 beta-geranylfarnesene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138226 GO:0043337 CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043337 Reactome:R-HSA-1483063|RHEA:32931|MetaCyc:RXN-8141 cardiolipin synthetase|cardiolipin synthase Catalysis of the reaction: CDP-diacylglycerol + phosphatidylglycerol = CMP + diphosphatidylglycerol. GO:0043336 site-specific telomere resolvase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043336 ResT|TelN Catalysis of a site-specific breakage and reunion reaction that generates two hairpin telomeres from a replicated telomere substrate. Occurs via a two-step transesterification with a protein-DNA intermediate similar to that used by topoisomerases and site-specific recombinases. GO:0018369 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018369 GO:0043339 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043339 GO:0043338 CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043338 EC:2.7.7.67|RHEA:25690 CDP-2,3-di-O-geranylgeranyl-sn-glycerol synthase Catalysis of the reaction: CTP + 2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate = CDP-2,3-di-O-geranylgeranyl-sn-glycerol. GO:0018366 chiral amino acid racemization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018366 The formation of a mixture of the two possible enantiomers from the D- or L-enantiomer of a chiral amino acid. CHEBI:138221 CDP-D-ribulose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138221 GO:0018365 protein-serine epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018365 RHEA:10660|MetaCyc:5.1.1.16-RXN|EC:5.1.1.16 protein-serine racemase activity Catalysis of the reaction: (protein)-L-serine = (protein)-D-serine. CHEBI:138220 N-hexadecanoyl-1,2-diheptadecanoyl-sn-glycero-3-phosphoethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138220 GO:0018368 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018368 GO:0018367 obsolete free L-amino acid racemization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018367 free L-amino acid racemization OBSOLETE. (Was not defined before being made obsolete). GO:0018362 peroxidase-heme linkage via dihydroxyheme-L-aspartyl ester-L-glutamyl ester biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018362 RESID:AA0279 peroxidase-haem linkage via dihydroxyhaem-L-aspartyl ester-L-glutamyl ester The covalent linkage of heme to peroxidase via dihydroxyheme-L-aspartyl ester-L-glutamyl ester. CHEBI:138225 CDP-D-ribose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138225 CHEBI:138224 (13R)-epi-8,13-epoxylabd-14-ene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138224 GO:0018361 peptidyl-glutamine 2-methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018361 RESID:AA0273 The methylation of glutamine to form 2-methyl-L-glutamine. CHEBI:138223 ent-copal-8-ol diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138223 GO:0018364 peptidyl-glutamine methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018364 The addition of a methyl group to a glutamine residue in a protein. CHEBI:138222 N-oleoyl-1,2-diheptadecanoyl-sn-glycero-3-phosphoethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138222 GO:0018363 peroxidase-heme linkage via dihydroxyheme-L-aspartyl ester-L-glutamyl ester-L-methionine sulfonium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018363 RESID:AA0280 peroxidase-heme linkage via dihydroxyheme-L-aspartyl ester-L-glutamyl ester-L-methionine sulphonium|peroxidase-haem linkage via dihydroxyhaem-L-aspartyl ester-L-glutamyl ester-L-methionine sulfonium The covalent linkage of heme to peroxidase via dihydroxyheme-L-aspartyl ester-L-glutamyl ester-L-methionine sulfonium. GO:0018380 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018380 GO:0018382 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018382 GO:0018381 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018381 GO:0033999 chondroitin B lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033999 EC:4.2.2.19|MetaCyc:4.2.2.19-RXN dermatan sulfate lyase activity|chonB|ChnB|chondroitinase B activity Catalysis of the reaction: dermatan sulfate = n 4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 4-sulfate. This reaction is the eliminative cleavage of dermatan sulfate containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucurosonyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups to yield a 4,5-unsaturated dermatan-sulfate disaccharide (DeltaUA-GalNAC-4S). Chondroitin sulfate B is also known as dermatan sulfate. GO:0033998 inulin fructotransferase (DFA-III-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033998 EC:4.2.2.18|MetaCyc:4.2.2.18-RXN inulin D-fructosyl-D-fructosyltransferase (forming alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride) activity|inulinase II activity|inulin fructotransferase (DFA-III-producing) activity|2,1-beta-D-fructan lyase (alpha-D-fructofuranose-beta-D-fructofuranose-1,2':2,3'-dianhydride-forming) activity|inulin D-fructosyl-D-fructosyltransferase (1,2':2,3'-dianhydride-forming) activity|inulin fructotransferase (depolymerizing, difructofuranose-1,2':2,3'-dianhydride-forming) activity|inulin fructotransferase (depolymerizing) activity|inulase II activity Catalysis of the reaction: [(2->1)-beta-D-fructosyl](n) = [(2->1)-beta-D-fructosyl](n-1) + alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride. This reaction is the production of alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride (DFA III) by successively eliminating the diminishing (2->1)-beta-D-fructan (inulin) chain from the terminal D-fructosyl-D-fructosyl disaccharide. GO:0033997 inulin fructotransferase (DFA-I-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033997 EC:4.2.2.17|MetaCyc:4.2.2.17-RXN inulin D-fructosyl-D-fructosyltransferase (1,2':1',2-dianhydride-forming) activity|inulin fructotransferase (depolymerizing, difructofuranose-1,2':2',1-dianhydride-forming) activity|inulin fructotransferase (DFA-I-producing) activity|2,1-beta-D-fructan lyase (alpha-D-fructofuranose-beta-D-fructofuranose-1,2':2,1'-dianhydride-forming) activity|inulin D-fructosyl-D-fructosyltransferase (forming alpha-D-fructofuranose beta-D-fructofuranose 1,2':1',2-dianhydride) activity Catalysis of the reaction: [(2->1)-beta-D-fructosyl](n) = [(2->1)-beta-D-fructosyl](n-1) + alpha-D-fructofuranose-beta-D-fructofuranose 1,2':1,2'-dianhydride. This reaction is the production of alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,1'-dianhydride (DFA I) by successively eliminating the diminishing (2->1)-beta-D-fructan (inulin) chain from the terminal D-fructosyl-D-fructosyl disaccharide. GO:0043344 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043344 GO:0043343 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043343 GO:0043346 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043346 GO:0043345 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043345 GO:0043340 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043340 GO:0043342 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043342 GO:0043341 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043341 CHEBI:138239 N-oleoyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138239 CHEBI:138238 pyrimidine ribonucleoside 5'-monophosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138238 CHEBI:138237 2-hydroxy-7,8-dihydropteroic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138237 GO:0043348 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043348 GO:0043347 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043347 GO:0043349 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043349 GO:0018377 protein myristoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018377 protein amino acid myristoylation The covalent attachment of a myristoyl group to a protein. GO:0033996 levan fructotransferase (DFA-IV-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033996 EC:4.2.2.16|MetaCyc:4.2.2.16-RXN levan fructotransferase activity|2,6-beta-D-fructan lyase (di-beta-D-fructofuranose-2,6':2',6-dianhydride-forming) activity|2,6-beta-D-fructan D-fructosyl-D-fructosyltransferase (forming di-beta-D-fructofuranose 2,6':2',6-dianhydride) activity Catalysis of the reaction: beta-D-fructopyranosyl-(2->6)-[D-fructofuranosyl-(2->6)]n-D-fructofuranoside = beta-D-fructopyranosyl-(2->6)-[D-fructofuranosyl-(2->6)](n-1)-D-fructofuranoside + di-beta-D-fructofuranose 2,6':2',6-dianhydride. This reaction is the production of di-beta-D-fructofuranose 2,6':2',6-dianhydride (DFA IV) by successively eliminating the diminishing (2->6)-beta-D-fructan (levan) chain from the terminal D-fructosyl-D-fructosyl disaccharide. CHEBI:138232 peregrinol diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138232 GO:0033995 anhydrosialidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033995 EC:4.2.2.15|MetaCyc:4.2.2.15-RXN sialglycoconjugate N-acylneuraminylhydrolase (2,7-cyclizing) activity|sialidase L activity|glycoconjugate sialyl-lyase (2,7-cyclizing) activity|anhydroneuraminidase activity Catalysis of the reaction: an N-acetylneuraminate glycoside = 2,7-anhydro-alpha-N-acetylneuraminate + an alpha-sialyl group. This reaction is the elimination of alpha-sialyl groups in N-acetylneuraminic acid glycosides, releasing 2,7-anhydro-alpha-N-acetylneuraminate. GO:0018376 peptidyl-asparagine hydroxylation to form L-erythro-beta-hydroxyasparagine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018376 RESID:AA0026 The hydroxylation of peptidyl-asparagine to form peptidyl-L-erythro-beta-hydroxyasparagine; catalyzed by peptide-aspartate beta-dioxygenase (EC:1.14.11.16). GO:0033994 glucuronan lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033994 EC:4.2.2.14|MetaCyc:4.2.2.14-RXN (1,4)-beta-D-glucuronan lyase activity Catalysis of the reaction: (1->4)-beta-D-glucuronan = an oligosaccharide with 4-deoxy-beta-D-gluc-4-enuronosyl end + (1->4)-beta-D-glucuronan. This reaction is the eliminative cleavage of (1->4)-beta-D-glucuronans to give oligosaccharides with 4-deoxy-beta-D-gluc-4-enuronosyl groups at their non-reducing ends. Complete degradation of glucuronans results in the formation of tetrasaccharides. GO:0018379 cytochrome c-heme linkage via heme-bis-L-cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018379 RESID:AA0134 cytochrome c-haem linkage via haem-bis-L-cysteine The linkage of cytochromes and other heme proteins to heme via heme-bis-L-cysteine. GO:0033993 response to lipid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033993 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus. GO:0018378 cytochrome c-heme linkage via heme-L-cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018378 RESID:AA0135 cytochrome c-haem linkage via haem-L-cysteine The linkage of cytochromes and other heme proteins to heme via heme-L-cysteine. GO:0033992 1,5-anhydro-D-fructose dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033992 RHEA:15725|MetaCyc:4.2.1.111-RXN|EC:4.2.1.111 AF dehydratase activity|AFDH|1,5-anhydro-D-fructose hydrolyase activity|1,5-anhydro-D-fructose 4-dehydratase activity|1,5-anhydro-D-fructose hydro-lyase activity|1,5-anhydro-D-fructose hydro-lyase (ascopyrone-M-forming) activity|1,5-anhydro-D-arabino-hex-2-ulose dehydratase activity Catalysis of the reaction: 1,5-anhydro-D-fructose = 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H2O. GO:0018373 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018373 GO:0033991 aldos-2-ulose dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033991 RHEA:12100|MetaCyc:4.2.1.110-RXN|EC:4.2.1.110 pyranosone dehydratase activity|1,5-anhydro-D-fructose dehydratase (microthecin-forming) activity|AUDH|1,5-anhydro-D-fructose hydro-lyase (microthecin-forming) activity Catalysis of the reactions: 1,5-anhydro-D-fructose = 2-hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one + H2O; (1a) 1,5-anhydro-D-fructose = 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H2O and (1b) 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose = 2-hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one. GO:0018372 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018372 GO:0018375 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018375 GO:0033990 ectoine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033990 KEGG_REACTION:R06979|MetaCyc:R103-RXN|EC:4.2.1.108|RHEA:17281 4-N-acetyl-L-2,4-diaminobutanoate hydro-lyase (L-ectoine-forming) activity|EctC|N-acetyldiaminobutyrate dehydratase activity|N4-acetyl-L-2,4-diaminobutanoate hydro-lyase (L-ectoine-forming) activity|L-ectoine synthase activity|N-acetyldiaminobutanoate dehydratase activity Catalysis of the reaction: N(4)-acetyl-L-2,4-diaminobutyrate = ectoine + H(2)O. CHEBI:138234 (13R)-manoyl oxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138234 GO:0018374 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018374 CHEBI:138233 9,13(R)-epoxylabd-14-ene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138233 GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033989 RHEA:18933|EC:4.2.1.107|Reactome:R-HSA-192331|Reactome:R-HSA-193535|MetaCyc:4.2.1.107-RXN (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA hydro-lyase activity|D-3-hydroxyacyl-CoA dehydratase activity|(24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA hydro-lyase [(24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA-forming] activity|46 kDa hydratase 2 activity Catalysis of the reaction: (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA = (24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA + H2O. GO:0033988 bile-acid 7alpha-dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033988 EC:4.2.1.106|RHEA:10436|KEGG_REACTION:R07318|MetaCyc:4.2.1.106-RXN 7alpha,12alpha-dihydroxy-3-oxochol-4-enoate hydro-lyase (12alpha-hydroxy-3-oxochola-4,6-dienoate-forming) activity|BA7 alpha dehydratase activity|7alpha,12alpha-dihydroxy-3-oxochol-4-enoate hydro-lyase activity Catalysis of the reaction: 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oate = 12alpha-hydroxy-3-oxochola-4,6-dien-24-oate + H(2)O. GO:0033987 2-hydroxyisoflavanone dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033987 RHEA:16445|EC:4.2.1.105|MetaCyc:RXN-3284 2,7,4'-trihydroxyisoflavanone hydro-lyase activity|2,7,4'-trihydroxyisoflavanone hydro-lyase (daidzein-forming) activity Catalysis of the reaction: 2,7,4'-trihydroxyisoflavanone = daidzein + H2O. GO:0033986 response to methanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033986 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methanol stimulus. GO:0043355 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043355 GO:0043354 enucleate erythrocyte maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043354 enucleate red blood cell maturation|enucleate RBC maturation A developmental process, independent of morphogenetic (shape) change, that is required for an enucleate erythrocyte to attain its fully functional state. An enucleate erythrocyte is an erythrocyte without a nucleus. GO:0043357 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043357 GO:0043356 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043356 GO:0043351 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043351 GO:0043350 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043350 GO:0043353 enucleate erythrocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043353 enucleate red blood cell differentiation|enucleate RBC differentiation The process in which a myeloid precursor cell acquires specialized features of an erythrocyte without a nucleus. An example of this process is found in Mus musculus. GO:0043352 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043352 CHEBI:138206 (13R)-S-cysteinylglycinyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138206 GO:0043359 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043359 GO:0018348 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018348 GO:0043358 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043358 GO:0018347 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018347 CHEBI:138209 (13R)-S-cysteinyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138209 GO:0018349 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018349 CHEBI:138208 carotenoid biosynthesis inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138208 GO:0018344 protein geranylgeranylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018344 C-terminal protein geranylgeranylation|protein amino acid geranylgeranylation The covalent attachment of a geranylgeranyl group to a protein. GO:0033985 acidocalcisome lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033985 The volume enclosed by the membranes of an acidocalcisome. GO:0033984 indole-3-glycerol-phosphate lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033984 EC:4.1.2.8|KEGG_REACTION:R02340|RHEA:14081|MetaCyc:4.1.2.8-RXN|MetaCyc:RXN0-2381 indole-3-glycerolphosphate D-glyceraldehyde-3-phosphate-lyase activity|TSA|indole synthase activity|BX1|tryptophan synthase alpha activity|tryptophan synthase alpha subunit activity|indole-3-glycerol phosphate lyase activity|(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate D-glyceraldehyde-3-phosphate-lyase (indole-forming) activity|IGL|indoleglycerolphosphate aldolase activity|indole glycerol phosphate hydrolase activity|(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate D-glyceraldehyde-3-phosphate-lyase activity Catalysis of the reaction: (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = indole + D-glyceraldehyde 3-phosphate. GO:0018343 protein farnesylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018343 C-terminal protein farnesylation|protein amino acid farnesylation The covalent attachment of a farnesyl group to a protein. GO:0033983 diaminobutyrate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033983 KEGG_REACTION:R07650|MetaCyc:4.1.1.86-RXN|EC:4.1.1.86|RHEA:15689 L-2,4-diaminobutyrate decarboxylase activity|L-2,4-diaminobutanoate carboxy-lyase (propane-1,3-diamine-forming) activity|L-2,4-diaminobutanoate carboxy-lyase activity|DABA DC Catalysis of the reaction: L-2,4-diaminobutyrate + H(+) = 1,3-diaminopropane + CO(2). CHEBI:2030 5-aminoimidazole-4-carboxamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_2030 GO:0018346 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018346 GO:0033982 3-dehydro-L-gulonate-6-phosphate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033982 KEGG_REACTION:R07125|RHEA:14353|EC:4.1.1.85|MetaCyc:RXN0-705 3-dehydro-L-gulonate-6-phosphate carboxy-lyase (L-xylulose-5-phosphate-forming) activity|SgaH|UlaD|SgbH|KGPDC|3-keto-L-gulonate 6-phosphate decarboxylase activity|3-dehydro-L-gulonate-6-phosphate carboxy-lyase activity Catalysis of the reaction: 3-dehydro-L-gulonate 6-phosphate + H(+) = L-xylulose 5-phosphate + CO(2). GO:0018345 protein palmitoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018345 protein amino acid palmitoylation The covalent attachment of a palmitoyl group to a protein. GO:0018340 peptidyl-O-(sn-1-glycerophosphoryl)-L-serine biosynthetic process from peptidyl-serine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018340 RESID:AA0264 peptidyl-O-(sn-1-glycerophosphoryl)-L-serine formation from peptidyl-serine|peptidyl-O-(sn-1-glycerophosphoryl)-L-serine synthesis from peptidyl-serine|peptidyl-O-(sn-1-glycerophosphoryl)-L-serine anabolism from peptidyl-serine The modification of peptidyl-serine to peptidyl-O-(sn-1-glycerophosphoryl)-L-serine. GO:0033981 D-dopachrome decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033981 RHEA:18441|MetaCyc:4.1.1.84-RXN|EC:4.1.1.84|KEGG_REACTION:R07313 phenylpyruvate tautomerase II activity|dopachrome conversion activity|D-dopachrome carboxy-lyase (5,6-dihydroxyindole-forming) activity|D-tautomerase activity|D-dopachrome carboxy-lyase activity|D-dopachrome tautomerase activity|dopachrome decarboxylase activity Catalysis of the reaction: D-dopachrome + H(+) = 5,6-dihydroxyindole + CO(2). GO:0033980 phosphonopyruvate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033980 KEGG_REACTION:R04053|MetaCyc:4.1.1.82-RXN|RHEA:20768|EC:4.1.1.82 3-phosphonopyruvate carboxy-lyase (2-phosphonoacetaldehyde-forming) activity|3-phosphonopyruvate carboxy-lyase activity Catalysis of the reaction: 3-phosphonopyruvate + 2 H(+) = CO(2) + phosphonoacetaldehyde. CHEBI:138202 (13R)-S-glutathionyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138202 GO:0018342 protein prenylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018342 C-terminal protein prenylation|protein amino acid prenylation The covalent attachment of a prenyl group to a protein; geranyl, farnesyl, or geranylgeranyl groups may be added. CHEBI:138201 18-hydroxyleukotriene B4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138201 GO:0018341 peptidyl-lysine modification to peptidyl-N6-pyruvic acid 2-iminyl-L-lysine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018341 peptidyl-N6-pyruvic acid 2-iminyl-L-lysine biosynthetic process|peptidyl-N6-pyruvic acid 2-iminyl-L-lysine biosynthesis|peptidyl-N6-pyruvic acid 2-iminyl-L-lysine anabolism|peptidyl-N6-pyruvic acid 2-iminyl-L-lysine synthesis|peptidyl-N6-pyruvic acid 2-iminyl-L-lysine formation The modification of peptidyl-lysine to form peptidyl-N6-pyruvic acid 2-iminyl-L-lysine. CHEBI:138200 1-heptanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138200 CHEBI:44185 methotrexate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_44185 GO:0018360 protein-heme P460 linkage via heme P460-bis-L-cysteine-L-lysine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018360 RESID:AA0271 protein-haem P460 linkage via haem P460-bis-L-cysteine-L-lysine The linkage of protein to heme P460 via heme P460-bis-L-cysteine-L-lysine. GO:0043360 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043360 GO:0033979 box H/ACA RNA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033979 box H/ACA sRNA metabolic process|box H/ACA snoRNA metabolic process The chemical reactions and pathways involving box H/ACA type small nucleolar RNA. GO:0033978 phosphonopyruvate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033978 MetaCyc:3.11.1.3-RXN|RHEA:16673|KEGG_REACTION:R08200|EC:3.11.1.3 PPH Catalysis of the reaction: 3-phosphonopyruvate + H(2)O = phosphate + pyruvate. GO:0033977 2-haloacid dehalogenase (configuration-retaining) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033977 MetaCyc:3.8.1.11-RXN|EC:3.8.1.11|RHEA:12072 2-haloalkanoic acid dehalogenase activity|2-haloalkanoid acid halidohydrolase activity|DL-2-haloacid dehalogenase activity|DL-DEXr Catalysis of the reactions: (S)-2-haloacid + H2O = (S)-2-hydroxyacid + halide, and (R)-2-haloacid + H2O = (R)-2-hydroxyacid + halide. GO:0033976 2-haloacid dehalogenase (configuration-inverting) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033976 MetaCyc:3.8.1.10-RXN|EC:3.8.1.10 DL-DEXi|DL-2-haloacid halidohydrolase (inversion of configuration) activity|2-haloalkanoic acid dehalogenase activity|DL-2-haloacid dehalogenase (inversion of configuration) activity|2-haloalkanoid acid halidohydrolase activity|DL-2-haloacid dehalogenase activity Catalysis of the reactions: (S)-2-haloacid + H2O = (R)-2-hydroxyacid + halide, and (R)-2-haloacid + H2O = (S)-2-hydroxyacid + halide. GO:0033975 (R)-2-haloacid dehalogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033975 MetaCyc:3.8.1.9-RXN|EC:3.8.1.9 (R)-2-haloacid halidohydrolase activity|2-haloalkanoic acid dehalogenase activity|D-DEX|D-2-haloacid dehalogenase activity|2-haloalkanoid acid halidohydrolase activity Catalysis of the reaction: (R)-2-haloacid + H2O = (S)-2-hydroxyacid + halide. GO:0043366 beta selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043366 The process in which successful recombination of a T cell receptor beta chain into a translatable protein coding sequence leads to rescue from apoptosis and subsequent proliferation of an immature T cell. GO:0043365 [formate-C-acetyltransferase]-activating enzyme activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043365 MetaCyc:TDCEACT-RXN|RHEA:19225|EC:1.97.1.4 formate acetyltransferase-glycine dihydroflavodoxin:S-adenosyl-L-methionine oxidoreductase (S-adenosyl-L-methionine cleaving) activity|formate C-acetyltransferase-glycine dihydroflavodoxin:S-adenosyl-L-methionine oxidoreductase (S-adenosyl-L-methionine cleaving)|formate-C-acetyltransferase-activating enzyme|[pyruvate formate-lyase]-activating enzyme activity|pyruvate formate-lyase-activating enzyme|PFL activase activity|PFL-glycine:S-adenosyl-L-methionine H transferase (flavodoxin-oxidizing, S-adenosyl-L-methionine-cleaving) activity|formate acetyltransferase activating enzyme activity Catalysis of the reaction: S-adenosyl-L-methionine + dihydroflavodoxin + [formate C-acetyltransferase]-glycine = 5'-deoxyadenosine + L-methionine + flavodoxin semiquinone + [formate C-acetyltransferase]-glycin-2-yl radical. GO:0043368 positive T cell selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043368 positive T-cell selection|positive T-lymphocyte selection|positive T lymphocyte selection The process of sparing immature T cells which react with self-MHC protein complexes with low affinity levels from apoptotic death. GO:0043367 CD4-positive, alpha-beta T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043367 CD4-positive, alpha-beta T lymphocyte differentiation|CD4-positive, alpha beta T cell differentiation|CD4-positive, alpha beta T cell development|CD4-positive, alpha-beta T-cell differentiation|CD4-positive, alpha-beta T-lymphocyte differentiation The process in which a relatively unspecialized T cell acquires specialized features of a mature CD4-positive, alpha-beta T cell. GO:0043362 nucleate erythrocyte maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043362 nucleate red blood cell maturation|nucleate RBC maturation A developmental process, independent of morphogenetic (shape) change, that is required for a nucleate erythrocyte to attain its fully functional state. A nucleate erythrocyte is an erythrocyte with a nucleus. GO:0043361 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043361 GO:0043364 glycyl-radical enzyme activating activity biolink:MolecularActivity go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0043364 EC:1.97.1.- catalysis of free radical formation Catalyzes the activation of an enzyme by generating an organic free radical on a glycine residue via a homolytic cleavage of S-adenosyl-L-methionine (SAM). GO:0043363 nucleate erythrocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043363 nucleate red blood cell differentiation|nucleate RBC differentiation The process in which a myeloid precursor cell acquires specializes features of an erythrocyte with a nucleus, as found in non-mammalian vertebrates such as birds. CHEBI:138218 1,2-diheptadecanoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138218 CHEBI:138217 1-heptanoyl-2-hexanoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138217 CHEBI:138216 1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138216 GO:0018359 protein-heme P460 linkage via heme P460-bis-L-cysteine-L-tyrosine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018359 RESID:AA0266 protein-haem P460 linkage via haem P460-bis-L-cysteine-L-tyrosine The linkage of protein to heme P460 via heme P460-bis-L-cysteine-L-tyrosine. GO:0018358 protein-phytochromobilin linkage via S-phytochromobilin-L-cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018358 RESID:AA0133 The linkage of the chromophore phytochromobilin to phycocyanin or allophycocyanin via S-phytochromobilin-L-cysteine. GO:0043369 CD4-positive or CD8-positive, alpha-beta T cell lineage commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043369 CD4-positive or CD8-positive, alpha-beta T lymphocyte lineage commitment|CD4-positive or CD8-positive, alpha-beta T-lymphocyte lineage commitment|CD4-positive or CD8-positive, alpha-beta T-cell lineage commitment|CD4-positive/CD8-positive, alpha-beta T cell lineage commitment The process in which an immature T cell commits to CD4-positive T cell lineage or the CD8-positive lineage of alpha-beta T cells. CHEBI:138219 ent-atiserene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138219 GO:0033974 nucleoside phosphoacylhydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033974 EC:3.6.1.24|MetaCyc:3.6.1.24-RXN nucleoside-5'-phosphoacylate acylhydrolase activity Catalysis of the hydrolysis of mixed phospho-anhydride bonds. GO:0018355 protein-phosphoribosyl dephospho-coenzyme A linkage via O-(phosphoribosyl dephospho-coenzyme A)-L-serine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018355 The formation of a protein-phosphoribosyl dephospho-coenzyme A linkage via O-(phosphoribosyl dephospho-coenzyme A)-L-serine. GO:0033973 dCTP deaminase (dUMP-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033973 MetaCyc:3.5.4.30-RXN|KEGG_REACTION:R07307|EC:3.5.4.30|RHEA:19205 dCTP aminohydrolase (dUMP-forming) activity Catalysis of the reaction: dCTP + 2 H(2)O = diphosphate + dUMP + H(+) + NH(4)(+). GO:0018354 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018354 GO:0033972 proclavaminate amidinohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033972 EC:3.5.3.22|KEGG_REACTION:R05357|RHEA:17001|MetaCyc:3.5.3.22-RXN PAH|proclavaminic acid amidino hydrolase activity|proclavaminate amidino hydrolase activity Catalysis of the reaction: amidinoproclavaminate + H(2)O = proclavaminate + urea. GO:0018357 protein-phycourobilin linkage via phycourobilin-bis-L-cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018357 RESID:AA0260 The linkage of the chromophore phycourobilin to phycoerythrins via phycourobilin-bis-L-cysteine. GO:0033971 hydroxyisourate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033971 EC:3.5.2.17|RHEA:23736|KEGG_REACTION:R06601|MetaCyc:3.5.2.17-RXN HIUHase activity|5-hydroxyisourate hydrolase activity|5-hydroxyisourate amidohydrolase activity Catalysis of the reaction: 5-hydroxyisourate + H(2)O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+). GO:0018356 protein-phycobiliviolin linkage via S-phycobiliviolin-L-cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018356 RESID:AA0258 The linkage of the chromophore phycobiliviolin to phycoerythrocyanin via S-phycobiliviolin-L-cysteine. GO:0018351 peptidyl-cysteine esterification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018351 The addition of an ester group to a cysteine residue in a protein. GO:0033970 N-malonylurea hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033970 KEGG_REACTION:R07629|EC:3.5.1.95|RHEA:17361|MetaCyc:3.5.1.95-RXN ureidomalonase activity|3-oxo-3-ureidopropanoate amidohydrolase (urea- and malonate-forming) activity Catalysis of the reaction: 3-oxo-3-ureidopropanoate + H(2)O = H(+) + malonate + urea. GO:0018350 protein esterification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018350 protein amino acid esterification The addition of an ester group to a protein amino acid. GO:0018353 protein-phycocyanobilin linkage via S-phycocyanobilin-L-cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018353 RESID:AA0131 The linkage of the chromophore phycocyanobilin to phycocyanin or allophycocyanin via S-phycocyanobilin-L-cysteine. CHEBI:138212 1-octadecanoyl-2-hexanoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138212 GO:0018352 protein-pyridoxal-5-phosphate linkage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018352 The formation of a linkage between a protein amino acid and pyridoxal-5-phosphate. CHEBI:138211 1-octadecanoyl-2-pentanoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138211 GO:0033969 gamma-glutamyl-gamma-aminobutyrate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033969 KEGG_REACTION:R07419|RHEA:19737|EC:3.5.1.94|MetaCyc:RXN0-3942 gamma-glutamyl-GABA hydrolase activity|PuuD|4-(glutamylamino)butanoate amidohydrolase activity|YcjL Catalysis of the reaction: 4-(L-gamma-glutamylamino)butanoate + H(2)O = 4-aminobutanoate + L-glutamate. GO:0043371 negative regulation of CD4-positive, alpha-beta T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043371 negative regulation of CD4-positive, alpha beta T cell development|down-regulation of CD4-positive, alpha beta T cell differentiation|negative regulation of CD4-positive, alpha beta T lymphocyte differentiation|inhibition of CD4-positive, alpha beta T cell differentiation|negative regulation of CD4-positive T-cell differentiation|negative regulation of CD4-positive T-lymphocyte differentiation|down regulation of CD4-positive, alpha beta T cell differentiation|negative regulation of CD4-positive, alpha beta T-cell differentiation|downregulation of CD4-positive, alpha beta T cell differentiation|negative regulation of CD4-positive, alpha beta T-lymphocyte differentiation Any process that stops, prevents, or reduces the frequency, rate, or extent of CD4-positive, alpha-beta T cell differentiation. GO:0043370 regulation of CD4-positive, alpha-beta T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043370 regulation of CD4-positive T-cell differentiation|regulation of CD4-positive T-lymphocyte differentiation|regulation of CD4-positive, alpha beta T cell differentiation|regulation of CD4-positive, alpha beta T-cell differentiation|regulation of CD4-positive, alpha beta T-lymphocyte differentiation|regulation of CD4-positive T lymphocyte differentiation|regulation of CD4-positive, alpha beta T cell development|regulation of CD4-positive, alpha beta T lymphocyte differentiation Any process that modulates the frequency, rate, or extent of CD4-positive, alpha-beta T cell differentiation. GO:0033968 glutaryl-7-aminocephalosporanic-acid acylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033968 EC:3.5.1.93|MetaCyc:3.5.1.93-RXN|RHEA:23508 GCA|cephalosporin acylase activity|glutaryl-7-aminocephalosporanic acid acylase activity|cephalosporin C acylase activity|CA|7beta-(4-carboxybutanamido)cephalosporanic acid acylase activity|GA|GL-7-ACA acylase activity|glutaryl-7-ACA acylase activity|(7R)-7-(4-carboxybutanamido)cephalosporanate amidohydrolase activity Catalysis of the reaction: (7R)-7-(4-carboxybutanamido)cephalosporanate + H2O = (7R)-7-aminocephalosporanate + glutarate. GO:0033967 box C/D RNA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033967 box C/D sRNA metabolic process|box C/D snoRNA metabolic process The chemical reactions and pathways involving box C/D type small nucleolar RNA. GO:0033966 N-substituted formamide deformylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033966 RHEA:12096|MetaCyc:3.5.1.91-RXN N-benzylformamide amidohydrolase activity|NfdA Catalysis of the reaction: N-benzylformamide + H2O = formate + benzylamine. GO:0033965 aculeacin-A deacylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033965 EC:3.5.1.70|MetaCyc:3.5.1.70-RXN aculeacin-A amidohydrolase activity|aculeacin A acylase activity Catalysis of the hydrolysis of the amide bond in aculeacin A and related neutral lipopeptide antibiotics, releasing the long-chain fatty acid side-chain. PR:000044637 calcitonin receptor protein biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000044637 A rhodopsin-like G-protein coupled receptor that is a translation product of the human CALCR or CALCRL genes, 1:1 orthologs thereof, or a semi-ortholog thereof. GO:0033964 glycosphingolipid deacylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033964 MetaCyc:3.5.1.69-RXN|EC:3.5.1.69 glycosphingolipid amidohydrolase activity|glycosphingolipid ceramide deacylase activity Catalysis of the hydrolysis of gangliosides and neutral glycosphingolipids, releasing fatty acids to form the lyso-derivatives. GO:0043377 negative regulation of CD8-positive, alpha-beta T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043377 down regulation of CD8-positive, alpha-beta T cell differentiation|negative regulation of CD8-positive, alpha beta T lymphocyte differentiation|downregulation of CD8-positive, alpha-beta T cell differentiation|negative regulation of CD8-positive, alpha-beta T cell development|down-regulation of CD8-positive, alpha-beta T cell differentiation|negative regulation of CD8-positive T-cell differentiation|negative regulation of CD8-positive T-lymphocyte differentiation|negative regulation of CD8-positive, alpha beta T-cell differentiation|inhibition of CD8-positive, alpha-beta T cell differentiation|negative regulation of CD8-positive, alpha beta T-lymphocyte differentiation|negative regulation of CD8-positive T lymphocyte differentiation Any process that stops, prevents, or reduces the rate of CD8-positive, alpha-beta T cell differentiation. GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043376 regulation of CD8-positive, alpha-beta T cell development|regulation of CD8-positive T-cell differentiation|regulation of CD8-positive T-lymphocyte differentiation|regulation of CD8-positive, alpha beta T-cell differentiation|regulation of CD8-positive, alpha beta T-lymphocyte differentiation|regulation of CD8-positive T lymphocyte differentiation|regulation of CD8-positive, alpha beta T lymphocyte differentiation Any process that modulates the frequency, rate, or extent of CD8-positive, alpha-beta T cell differentiation. GO:0043379 memory T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043379 memory T-cell differentiation|memory T-lymphocyte differentiation|memory T cell development|memory T lymphocyte differentiation The process in which a newly activated T cell acquires specialized features of a memory T cell. GO:0043378 positive regulation of CD8-positive, alpha-beta T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043378 positive regulation of CD8-positive, alpha beta T lymphocyte differentiation|up regulation of CD8-positive, alpha-beta T cell differentiation|positive regulation of CD8-positive, alpha-beta T cell development|activation of CD8-positive, alpha-beta T cell differentiation|positive regulation of CD8-positive T-cell differentiation|stimulation of CD8-positive, alpha-beta T cell differentiation|positive regulation of CD8-positive T-lymphocyte differentiation|positive regulation of CD8-positive, alpha beta T-cell differentiation|positive regulation of CD8-positive, alpha beta T-lymphocyte differentiation|up-regulation of CD8-positive, alpha-beta T cell differentiation|positive regulation of CD8-positive T lymphocyte differentiation|upregulation of CD8-positive, alpha-beta T cell differentiation Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell differentiation. GO:0043373 CD4-positive, alpha-beta T cell lineage commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043373 CD4-positive, alpha-beta T-lymphocyte lineage commitment|CD4-positive, alpha-beta T-cell lineage commitment|CD4-positive, alpha-beta T lymphocyte lineage commitment The process in which an immature T cell becomes committed to becoming a CD4-positive, alpha-beta T cell. PR:000044631 adrenoceptor protein biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000044631 A rhodopsin-like G-protein coupled receptor that is a translation product of the human ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, or ADRB3 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. GO:0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043372 stimulation of CD4-positive, alpha beta T cell differentiation|positive regulation of CD4-positive, alpha beta T lymphocyte differentiation|up-regulation of CD4-positive, alpha beta T cell differentiation|positive regulation of CD4-positive T-cell differentiation|positive regulation of CD4-positive, alpha beta T cell differentiation|positive regulation of CD4-positive T-lymphocyte differentiation|positive regulation of CD4-positive, alpha beta T-cell differentiation|upregulation of CD4-positive, alpha beta T cell differentiation|positive regulation of CD4-positive, alpha beta T-lymphocyte differentiation|positive regulation of CD4-positive T lymphocyte differentiation|up regulation of CD4-positive, alpha beta T cell differentiation|positive regulation of CD4-positive, alpha beta T cell development|activation of CD4-positive, alpha beta T cell differentiation Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell differentiation. PR:000044630 corticotropin-releasing factor receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000044630 A secretin-like G-protein coupled receptor that is a translation product of the human CRHR1 or CRHR2 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. GO:0043375 CD8-positive, alpha-beta T cell lineage commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043375 CD8-positive, alpha-beta T cell fate commitment|CD8-positive, alpha-beta T-lymphocyte lineage commitment|CD8-positive, alpha-beta T-cell lineage commitment|CD8-positive, alpha-beta T lymphocyte lineage commitment The process in which an immature T cell becomes committed to becoming a CD8-positive, alpha-beta T cell. GO:0043374 CD8-positive, alpha-beta T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043374 CD8-positive, alpha-beta T-cell differentiation|CD8-positive, alpha-beta T-lymphocyte differentiation|CD8-positive, alpha-beta T cell development|CD8-positive, alpha-beta T lymphocyte differentiation The process in which a relatively unspecialized T cell acquires specialized features of a mature CD8-positive, alpha-beta T cell. GO:0018329 obsolete enzyme active site formation via N6-(phospho-5'-adenosine)-L-lysine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018329 RESID:AA0227 OBSOLETE. The transient adenylylation of lysine to form N6-(phospho-5'-adenosine)-L-lysine, found in the active site of DNA ligase and RNA ligase. GO:0018326 obsolete enzyme active site formation via S-acetyl-L-cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018326 RESID:AA0056 OBSOLETE. The transient acetylation of peptidyl-cysteine to form S-acetyl-L-cysteine. GO:0018325 obsolete enzyme active site formation via S-phospho-L-cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018325 RESID:AA0034 OBSOLETE. The transient phosphorylation of peptidyl-cysteine to form S-phospho-L-cysteine. GO:0018328 obsolete enzyme active site formation via 3'-phospho-L-histidine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018328 RESID:AA0036 OBSOLETE. The transient phosphorylation of peptidyl-histidine to form 3'-phospho-L-histidine (otherwise known as pi-phosphohistidine, pros-phosphohistidine). GO:0018327 obsolete enzyme active site formation via 1'-phospho-L-histidine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018327 RESID:AA0035 OBSOLETE. The transient phosphorylation of peptidyl-histidine to form 1'-phospho-L-histidine (otherwise known as tau-phosphohistidine, tele-phosphohistidine). GO:0033963 cholesterol-5,6-oxide hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033963 MetaCyc:RXN-8651|MetaCyc:RXN-8650|EC:3.3.2.11 ChEH|5,6alpha-epoxy-5alpha-cholestan-3beta-ol hydrolase activity|cholesterol-epoxide hydrolase activity Catalysis of the reactions: 5,6alpha-epoxy-5alpha-cholestan-3beta-ol + H2O = cholestane-3beta-5alpha,6beta-triol, and 5,6beta-epoxy-5beta-cholestan-3beta-ol + H2O = cholestane-3beta-5alpha,6beta-triol. GO:0018322 protein tyrosinylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018322 protein amino acid tyrosinylation The addition of a tyrosine molecule to a protein amino acid. GO:0018321 protein glucuronylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018321 protein amino acid glucuronylation The modification of a protein by amino acid glucuronylation, the addition of a glucuronate group, the uronic acid derived from glucose. GO:0033962 P-body assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033962 P body biogenesis|cytoplasmic mRNA processing body assembly|P body assembly The aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body. GO:0033961 cis-stilbene-oxide hydrolase activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0033961 Reactome:R-HSA-5694077|EC:3.3.2.9|MetaCyc:3.3.2.9-RXN|RHEA:23900 microsomal epoxide hydratase activity|benzo[a]pyrene-4,5-oxide hydratase activity|arene-oxide hydratase activity|cis-epoxide hydrolase activity|epoxide hydrase activity|benzo(a)pyrene-4,5-epoxide hydratase activity|aryl epoxide hydrase activity|microsomal epoxide hydrase activity|microsomal epoxide hydrolase activity|epoxide hydratase activity|mEH Catalysis of the reaction: cis-stilbene oxide + H2O = (+)-(1R,2R)-1,2-diphenylethane-1,2-diol. GO:0018324 obsolete enzyme active site formation via L-cysteine sulfenic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018324 RESID:AA0205 enzyme active site formation via L-cysteine sulphenic acid OBSOLETE. The oxidation of peptidyl-cysteine to form peptidyl-L-cysteine sulfenic acid, found in the active site of NADH peroxidase, nitrile hydratase, and peptide methionine sulfoxide reductase. GO:0033960 N-methyl nucleosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033960 RHEA:10880|MetaCyc:RXN-7597|KEGG_REACTION:R07918|EC:3.2.2.25 7-methylxanthosine nucleosidase activity|N-methyl nucleoside hydrolase activity|7-methylxanthosine ribohydrolase activity|methylpurine nucleosidase activity|N-MeNase activity Catalysis of the reaction: 7-methylxanthosine + H(2)O = 7-methylxanthine + H(+) + ribofuranose. GO:0018323 obsolete enzyme active site formation via L-cysteine sulfinic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018323 RESID:AA0262 enzyme active site formation via L-cysteine sulphinic acid OBSOLETE. The oxidation of peptidyl-cysteine to form peptidyl-L-cysteine sulfinic acid. GO:0018320 obsolete enzyme active site formation via S-methyl-L-cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018320 RESID:AA0234 OBSOLETE. The transient methylation of peptidyl-cysteine to form S-methyl-L-cysteine. GO:0043380 regulation of memory T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043380 regulation of memory T-cell differentiation|regulation of memory T-lymphocyte differentiation|regulation of memory T cell development|regulation of memory T lymphocyte differentiation Any process that modulates the frequency, rate, or extent of memory T cell differentiation. GO:0033959 deoxyribodipyrimidine endonucleosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033959 EC:3.2.2.17|MetaCyc:3.2.2.17-RXN deoxy-D-ribocyclobutadipyrimidine polynucleotidodeoxyribohydrolase activity|PD-DNA glycosylase activity|endonuclease V activity|T4-induced UV endonuclease activity|pyrimidine dimer DNA glycosylase activity|deoxyribonucleate pyrimidine dimer glycosidase activity|pyrimidine dimer DNA-glycosylase activity Catalysis of the cleavage of the N-glycosidic bond between the 5'-pyrimidine residue in cyclobutadipyrimidine (in DNA) and the corresponding deoxy-D-ribose residue. GO:0043382 positive regulation of memory T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043382 up-regulation of memory T cell differentiation|positive regulation of memory T-cell differentiation|upregulation of memory T cell differentiation|positive regulation of memory T-lymphocyte differentiation|up regulation of memory T cell differentiation|positive regulation of memory T cell development|activation of memory T cell differentiation|stimulation of memory T cell differentiation|positive regulation of memory T lymphocyte differentiation Any process that activates or increases the frequency, rate or extent of memory T cell differentiation. GO:0033958 DNA-deoxyinosine glycosylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033958 EC:3.2.2.15|MetaCyc:3.2.2.15-RXN hypoxanthine-DNA glycosylase activity|deoxyribonucleic acid glycosylase activity|DNA(hypoxanthine) glycohydrolase activity|DNA-deoxyinosine glycosidase activity|DNA-deoxyinosine deoxyribohydrolase activity Catalysis of the hydrolysis of DNA and polynucleotides, releasing free hypoxanthine. GO:0033957 lambda-carrageenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033957 EC:3.2.1.162|MetaCyc:3.2.1.162-RXN endo-beta-1,4-carrageenose 2,6,2'-trisulfate-hydrolase activity Catalysis of the endohydrolysis of beta-1,4-linkages in the backbone of lambda-carrageenan, resulting in the tetrasaccharide alpha-D-Galp2,6S2-(1->3)-beta-D-Galp2S-(1->4)-alpha-D-Galp2,6S2-(1->3)-D-Galp2S. GO:0043381 negative regulation of memory T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043381 negative regulation of memory T-cell differentiation|down regulation of memory T cell differentiation|downregulation of memory T cell differentiation|negative regulation of memory T-lymphocyte differentiation|negative regulation of memory T cell development|down-regulation of memory T cell differentiation|negative regulation of memory T lymphocyte differentiation|inhibition of memory T cell differentiation Any process that stops, prevents, or reduces the rate of memory T cell differentiation. PR:000044643 complement peptide receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000044643 A rhodopsin-like G-protein coupled receptor that is a translation product of the human C3AR1, C5AR1, or C5AR2 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. GO:0033956 beta-apiosyl-beta-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033956 EC:3.2.1.161|MetaCyc:RXN-9156|RHEA:21488|MetaCyc:3.2.1.161-RXN isoflavonoid 7-O-beta-apiosyl-glucoside beta-glucosidase activity|isoflavonoid-7-O-beta[D-apiosyl-(1->6)-beta-D-glucoside] disaccharidase activity|furcatin hydrolase activity|7-[beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranosyloxy]isoflavonoid beta-D-apiofuranosyl-(1->6)-D-glucohydrolase activity Catalysis of the reaction: 7-[beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranosyloxy]isoflavonoid + H2O = a 7-hydroxyisoflavonoid + beta-D-apiofuranosyl-(1->6)-D-glucose. GO:0033955 mitochondrial DNA inheritance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033955 mitochondrial chromosome segregation|mitochondrial DNA segregation The process in which copies of the mitochondrial genome are distributed into daughter mitochondria upon mitochondrial fission. GO:0033954 alpha-neoagaro-oligosaccharide hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033954 MetaCyc:3.2.1.159-RXN|EC:3.2.1.159 alpha-neoagarooligosaccharide hydrolase activity|alpha-neoagaro-oligosaccharide 3-glycohydrolase activity|alpha-NAOS hydrolase activity Catalysis of the hydrolysis of the 1,3-alpha-L-galactosidic linkages of neoagaro-oligosaccharides that are smaller than a hexamer, yielding 3,6-anhydro-L-galactose and D-galactose. GO:0033953 alpha-agarase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033953 MetaCyc:3.2.1.158-RXN|EC:3.2.1.158 agarose 3-glycanohydrolase activity|agarase activity|agarase A33 activity Catalysis of the endohydrolysis of 1,3-alpha-L-galactosidic linkages in agarose, yielding agarotetraose as the major product. GO:0043388 positive regulation of DNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043388 upregulation of DNA binding|up regulation of DNA binding|activation of DNA binding|stimulation of DNA binding|up-regulation of DNA binding Any process that increases the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid). GO:0043387 mycotoxin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043387 mycotoxin degradation|mycotoxin breakdown|mycotoxin catabolism The chemical reactions and pathways resulting in the breakdown of a mycotoxin, any poisonous substance produced by a fungus. GO:0043389 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043389 GO:0043384 pre-T cell receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043384 pre-T-lymphocyte receptor complex|pre-TCR complex|pre-T-cell receptor complex|pre-T lymphocyte receptor complex A receptor complex found on immature T cells consisting of a T cell receptor beta chain and the pre-TCR-alpha chain, along with additional signaling components including CD3 family members and additional signaling proteins. GO:0043383 negative T cell selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043383 negative T-lymphocyte selection|negative T lymphocyte selection|negative T-cell selection The process of elimination of immature T cells which react strongly with self-antigens. GO:0043386 mycotoxin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043386 mycotoxin anabolism|mycotoxin biosynthesis|mycotoxin synthesis|mycotoxin formation The chemical reactions and pathways resulting in the formation of a mycotoxin, any poisonous substance produced by a fungus. GO:0043385 mycotoxin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043385 mycotoxin metabolism The chemical reactions and pathways involving a mycotoxin, any poisonous substance produced by a fungus. GO:0018337 obsolete enzyme active site formation via L-2',4',5'-topaquinone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018337 enzyme active site formation via L-2',4',5'-topaquinone OBSOLETE. (Was not defined before being made obsolete). GO:0018336 peptidyl-tyrosine hydroxylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018336 The hydroxylation of peptidyl-tyrosine to form peptidyl-dihydroxyphenylalanine. GO:0018339 peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018339 RESID:AA0232 peptidyl-L-beta-methylthioaspartic acid anabolism from peptidyl-aspartic acid|peptidyl-L-beta-methylthioaspartic acid synthesis from peptidyl-aspartic acid|peptidyl-L-beta-methylthioaspartic acid formation from peptidyl-aspartic acid|peptidyl-aspartic acid methylthiolation The modification of peptidyl-aspartic acid to form peptidyl-L-beta-methylthioaspartic acid, typical of bacterial ribosomal protein S12. GO:0018338 obsolete protein amino acid cinnamylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018338 protein amino acid cinnamylation OBSOLETE. The modification of a protein amino acid by cinnamylation. GO:0018333 obsolete enzyme active site formation via O-phospho-L-threonine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018333 RESID:AA0038 OBSOLETE. The transient phosphorylation of peptidyl-threonine to form O-phospho-L-threonine. GO:0033952 iota-carrageenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033952 MetaCyc:3.2.1.157-RXN|EC:3.2.1.157 iota-carrageenan 4-beta-D-glycanohydrolase (configuration-inverting) activity Catalysis of the endohydrolysis of 1,4-beta-D-linkages between D-galactose 4-sulfate and 3,6-anhydro-D-galactose-2-sulfate in iota-carrageenans. GO:0018332 obsolete enzyme active site formation via O-(phospho-5'-adenosine)-L-threonine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018332 RESID:AA0267 OBSOLETE. The transient adenylylation of threonine to form N6-(phospho-5'-adenosine)-L-threonine, found in the active site of bovine phosphodiesterase I. GO:0033951 oligosaccharide reducing-end xylanase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033951 MetaCyc:3.2.1.156-RXN|EC:3.2.1.156 Rex|reducing end xylose-releasing exo-oligoxylanase activity|beta-D-xylopyranosyl-(1->4)-beta-D-xylopyranosyl-(1->4)-beta-D-xylopyranose reducing-end xylanase activity Catalysis of the hydrolysis of 1,4-beta-D-xylose residues from the reducing end of oligosaccharides. GO:0033950 xyloglucan-specific exo-beta-1,4-glucanase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033950 MetaCyc:3.2.1.155-RXN|EC:3.2.1.155 [(1->6)-alpha-D-xylo]-(1->4)-beta-D-glucan exo-glucohydrolase activity|Cel74A Catalysis of the reaction: xyloglucan + H2O = xyloglucan oligosaccharides. This reaction is the exohydrolysis of 1,4-beta-D-glucosidic linkages in xyloglucan. GO:0018335 protein succinylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018335 protein amino acid succinylation The modification of a protein by the addition of a succinyl group (CO-CH2-CH2-CO) to an amino acid residue. GO:0018334 obsolete enzyme active site formation via O4'-phospho-L-tyrosine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018334 RESID:AA0039 OBSOLETE. The transient phosphorylation of peptidyl-tyrosine to form O-phospho-L-tyrosine. GO:0018331 obsolete enzyme active site formation via O-phospho-L-serine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018331 RESID:AA0037 OBSOLETE. The transient phosphorylation of peptidyl-serine to form O-phospho-L-serine. GO:0018330 obsolete enzyme active site formation via N6-(phospho-5'-guanosine)-L-lysine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018330 RESID:AA0228 OBSOLETE. The transient guanylylation of lysine to form N6-(phospho-5'-guanosine)-L-lysine, found in the guanylyltransferase active site of mRNA capping enzyme. GO:0033949 fructan beta-(2,6)-fructosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033949 MetaCyc:3.2.1.154-RXN|EC:3.2.1.154 beta-(2,6)-fructan exohydrolase activity|beta-(2,6)-D-fructan fructohydrolase activity|6-FEH Catalysis of the hydrolysis of terminal, non-reducing (2->6) linked beta-D-fructofuranose residues in fructans. GO:0043391 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043391 GO:0033948 fructan beta-(2,1)-fructosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033948 MetaCyc:3.2.1.153-RXN|EC:3.2.1.153 beta-(2,1)-D-fructan fructohydrolase activity|1-fructan exohydrolase activity|beta-(2,1)-linkage-specific fructan-beta-fructosidase activity|1-FEH II|1-FEH w2|1-FEH w1|beta-(2,1)-fructan exohydrolase activity Catalysis of the hydrolysis of terminal, non-reducing (2->1) linked beta-D-fructofuranose residues in fructans. GO:0043390 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043390 GO:0043393 regulation of protein binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043393 Any process that modulates the frequency, rate or extent of protein binding. GO:0033947 mannosylglycoprotein endo-beta-mannosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033947 MetaCyc:3.2.1.152-RXN|EC:3.2.1.152 endo-beta-mannosidase activity Catalysis of the hydrolysis of the alpha-D-mannosyl-(1->6)-beta-D-mannosyl-(1->4)-beta-D-N-acetylglucosaminyl-(1->4)-beta-D-N-acetylglucosaminyl sequence of glycoprotein to alpha-D-mannosyl-(1->6)-D-mannose and beta-D-N-acetylglucosaminyl-(1->4)-beta-D-N-acetylglucosaminyl sequences. GO:0043392 negative regulation of DNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043392 inhibition of DNA binding|down regulation of DNA binding|downregulation of DNA binding|down-regulation of DNA binding Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid). GO:0033946 xyloglucan-specific endo-beta-1,4-glucanase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033946 MetaCyc:3.2.1.151-RXN|EC:3.2.1.151 xyloglucanase activity|XEG|1,4-beta-D-glucan glucanohydrolase activity|XH|xyloglucan endo-beta-1,4-glucanase activity|xyloglucanendohydrolase activity|[(1->6)-beta-D-xylo]-(1->4)-beta-D-glucan glucanohydrolase activity Catalysis of the reaction: xyloglucan + H2O = xyloglucan oligosaccharides. This reaction is the endohydrolysis of (1->4)-beta-D-glucosidic linkages in xyloglucan. GO:0008989 rRNA (guanine-N1-)-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008989 MetaCyc:RRNA-GUANINE-N1--METHYLTRANSFERASE-RXN ribosomal ribonucleate guanine 1-methyltransferase activity|S-adenosyl-L-methionine:rRNA (guanine-1-N-)-methyltransferase activity|S-adenosyl-L-methionine:rRNA (guanine-N1-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N1-methylguanine. GO:0033945 oligoxyloglucan reducing-end-specific cellobiohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033945 MetaCyc:3.2.1.150-RXN|EC:3.2.1.150 oligoxyloglucan reducing end-specific cellobiohydrolase activity|oligoxyloglucan reducing-end cellobiohydrolase activity Catalysis of the hydrolysis of cellobiose from the reducing end of xyloglucans consisting of a beta-(1->4) linked glucan carrying alpha-D-xylosyl groups on O-6 of the glucose residues. To be a substrate, the first residue must be unsubstituted, the second residue may bear a xylosyl group, whether further glycosylated or not, and the third residue, which becomes the new terminus by the action of the enzyme, is preferably xylosylated, but this xylose residue must not be further substituted. GO:0033944 beta-galactofuranosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033944 MetaCyc:3.2.1.146-RXN|EC:3.2.1.146 exo-beta-galactofuranosidase activity|beta-D-galactofuranosidase activity|beta-D-galactofuranoside hydrolase activity|exo-beta-D-galactofuranosidase activity Catalysis of the hydrolysis of terminal non-reducing beta-D-galactofuranosides, releasing galactose. GO:0008988 rRNA (adenine-N6-)-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008988 gene ksgA methyltransferase|ribonucleic acid-adenine (N(6)) methylase activity|ribosomal ribonucleate adenine 6-methyltransferase activity|ribonucleic acid-adenine (N6) methylase activity|S-adenosyl-L-methionine:rRNA (adenine-6-N-)-methyltransferase activity|S-adenosyl-L-methionine:rRNA (adenine-N6-)-methyltransferase activity|ErmC 23S rRNA methyltransferase Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N6-methyladenine. GO:0033943 galactan 1,3-beta-galactosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033943 MetaCyc:3.2.1.145-RXN|EC:3.2.1.145 galactan (1,3)-beta-D-galactosidase activity|galactan (1->3)-beta-D-galactosidase activity Catalysis of the hydrolysis of terminal, non-reducing beta-D-galactose residues in (1->3)-beta-D-galactopyranans. GO:0008987 quinolinate synthetase A activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008987 MetaCyc:QUINOLINATE-SYNTHA-RXN|RHEA:25888 Catalysis of the reaction: iminoaspartate + dihydroxy-acetone-phosphate = quinolinate + 2 H2O + phosphate. GO:0008986 pyruvate, water dikinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008986 EC:2.7.9.2|MetaCyc:PEPSYNTH-RXN|KEGG_REACTION:R00199|RHEA:11364 PEP synthetase activity|pyruvate-water dikinase (phosphorylating)|phosphoenolpyruvate synthase activity|ATP:pyruvate, water phosphotransferase activity|phoephoenolpyruvate synthetase activity|phosphoenolpyruvic synthase activity|pyruvate,water dikinase activity|water pyruvate dikinase activity|PEP synthase activity|phosphopyruvate synthetase activity Catalysis of the reaction: ATP + H(2)O + pyruvate = AMP + 3 H(+) + phosphate + phosphoenolpyruvate. GO:0033942 4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033942 MetaCyc:3.2.1.141-RXN|EC:3.2.1.141 4-alpha-D-{(1->4)-alpha-D-glucano}trehalose glucanohydrolase (trehalose-producing) activity|maltooligosyl trehalose trehalohydrolase activity|4-alpha-D-{(1,4)-alpha-D-glucano}trehalose glucanohydrolase (trehalose-producing) activity|malto-oligosyltrehalose trehalohydrolase activity Catalysis of the hydrolysis of alpha-(1->4)-D-glucosidic linkage in 4-alpha-D-{(1->4)-alpha-D-glucanosyl}n trehalose to yield trehalose and alpha-(1->4)-D-glucan. GO:0008985 obsolete pyruvate dehydrogenase (cytochrome) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008985 pyruvate:ferricytochrome-b1 oxidoreductase activity|pyruvate:ubiquinone-8-oxidoreductase activity|pyruvic (cytochrome b1) dehydrogenase activity|pyruvate dehydrogenase (cytochrome) activity OBSOLETE. Catalysis of the reaction: pyruvate + ferricytochrome b1 + H2O = CO2 + acetate + ferrocytochrome b1. GO:0043399 tRNA A64-2'-O-ribosylphosphate transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043399 initiator tRNA phosphoribosyl-transferase activity Catalysis of the transfer of a phosphoribosyl group from 5'-phosphoribosyl-1'-pyrophosphate to position 64 of initiator tRNA. GO:0008984 protein-glutamate methylesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008984 RESID:AA0072|MetaCyc:MCPMETEST-RXN|EC:3.1.1.61|RHEA:23236 methyl-accepting chemotaxis protein methyl-esterase activity|protein-L-glutamate-5-O-methyl-ester acylhydrolase activity|CheB methylesterase activity|protein-L-glutamate-O5-methyl-ester acylhydrolase activity|methylesterase CheB activity|chemotaxis-specific methylesterase activity Catalysis of the reaction: protein L-glutamate O(5)-methyl ester + H2O = protein L-glutamate + methanol. GO:0043398 HLH domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043398 Interacting selectively and non-covalently with Helix Loop Helix, a domain of 40-50 residues that occurs in specific DNA-binding proteins that act as transcription factors. The domain is formed of two amphipathic helices joined by a variable length linker region that can form a loop and it mediates protein dimerization. GO:0008983 protein-glutamate O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008983 MetaCyc:CHER-RXN|RESID:AA0072|EC:2.1.1.80|RHEA:24452 protein O-methyltransferase activity|protein carboxyl-methylase activity|protein carboxymethylase activity|protein(carboxyl)methyltransferase activity|protein carboxylmethyltransferase II|MCP methyltransferase II|S-adenosylmethionine-glutamyl methyltransferase activity|S-adenosylmethionine:protein-carboxyl O-methyltransferase activity|S-adenosyl-L-methionine:protein-L-glutamate O-methyltransferase activity|methyl-accepting chemotaxis protein methyltransferase II|MCP methyltransferase I|protein carboxymethyltransferase activity|protein carboxyl-O-methyltransferase activity|protein methylase II|protein(aspartate)methyltransferase activity|methyl-accepting chemotaxis protein O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + protein L-glutamate = S-adenosyl-L-homocysteine + protein L-glutamate 5-methyl ester; this reaction is the methylation of peptidyl-L-glutamate to form peptidyl-L-glutamate 5-methyl ester. GO:0008982 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008982 MetaCyc:2.7.1.69-RXN|EC:2.7.1.69 PEP--sugar phosphotransferase enzyme II activity|phosphotransfer-driven group translocator|protein-Npi-phosphohistidine:sugar N-pros-phosphotransferase activity|PTS transporter|phosphohistidinoprotein-hexose phosphotransferase activity|protein-Npi-phosphohistidine-sugar phosphotransferase activity|gene bglC RNA formation factors|protein, specific or class, gene bglC|PTS permease activity|PEP-dependent phosphotransferase enzyme II|group translocator activity|phosphoprotein factor-hexose phosophotransferase activity|protein-Npi-phospho-L-histidine:sugar N-pros-phosphotransferase activity|gene glC proteins|phosphoenolpyruvate-sugar phosphotransferase enzyme II|protein-Npi-phospho-L-histidine:sugar Npi-phosphotransferase activity|protein-Np-phosphohistidine-sugar phosphotransferase activity|enzyme II of the phosphotransferase system|ribonucleic acid formation factor, gene glC|sucrose phosphotransferase system II|phosphotransferase, phosphohistidinoprotein-hexose activity|phosphohistidinoprotein-hexose phosphoribosyltransferase activity|enzyme IIl4ac Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sugar(out) = protein histidine + sugar phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. GO:0008981 obsolete protease IV activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008981 protease IV activity OBSOLETE. (Was not defined before being made obsolete). GO:0043395 heparan sulfate proteoglycan binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043395 heparin proteoglycan binding Interacting selectively and non-covalently with a heparan sulfate proteoglycan, any proteoglycan containing heparan sulfate as the glycosaminoglycan carbohydrate unit. GO:0008980 propionate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008980 EC:2.7.2.15|RHEA:23148 propanoate kinase activity|ATP:propanoate phosphotransferase activity|PduW|TdcD Catalysis of the reaction: ATP + propanoate = ADP + propanoyl phosphate. GO:0043394 proteoglycan binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043394 Interacting selectively and non-covalently with a proteoglycan, any glycoprotein in which the carbohydrate units are glycosaminoglycans. GO:0043397 regulation of corticotropin-releasing hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043397 regulation of CRH secretion|regulation of CRF secretion|regulation of corticotropin-releasing factor secretion Any process that modulates the frequency, rate or extent of corticotropin-releasing hormone secretion. GO:0043396 corticotropin-releasing hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043396 CRH secretion|CRF secretion|corticotropin-releasing factor secretion The regulated release of corticotropin-releasing hormone (CRH), a polypeptide hormone involved in the stress response. CRH is produced by the hypothalamus and stimulates corticotropic cells of the anterior lobe of the pituitary to produce corticotropic hormone (CTH) and other biologically active substances e.g. 2-endorphin, release of CRH is affected by serum levels of cortisol, by stress and by the sleep/wake cycle. CHEBI:58794 (3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58794 GO:0018308 obsolete enzyme active site formation via N6-pyruvic acid 2-iminyl-L-lysine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018308 enzyme active site formation via N6-pyruvic acid 2-iminyl-L-lysine OBSOLETE. The transient modification of lysine by pyruvate to form N6-pyruvic acid 2-iminyl-L-lysine, found in the active site of dihydrodipicolinate synthase. GO:0018307 obsolete enzyme active site formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018307 OBSOLETE. The modification of part of an enzyme to form the active site. CHEBI:58793 2-O-sinapoyl-D-glucarate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58793 CHEBI:58792 2-azaniumyl-2-deoxyisochorismate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58792 GO:0018309 protein-FMN linkage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018309 The formation of a linkage between a protein amino acid and flavin mononucleotide (FMN). GO:0018304 iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-aspartato tetrairon tetrasulfide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018304 RESID:AA0286 iron incorporation into iron-sulphur cluster via tris-L-cysteinyl-L-aspartato tetrairon tetrasulphide The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-aspartato tetrairon tetrasulfide. CHEBI:58790 3-(1-carboxylatovinyloxy)anthranilate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58790 GO:0018303 iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-N3'-histidino tetrairon tetrasulfide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018303 RESID:AA0285 iron incorporation into iron-sulphur cluster via tris-L-cysteinyl-L-N3'-histidino tetrairon tetrasulphide The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-N3'-histidino tetrairon tetrasulfide. GO:0018306 iron incorporation into iron-sulfur cluster via bis-L-cysteinyl-L-N3'-histidino-L-serinyl tetrairon tetrasulfide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018306 RESID:AA0289 iron incorporation into iron-sulphur cluster via bis-L-cysteinyl-L-N3'-histidino-L-serinyl tetrairon tetrasulphide The incorporation of iron into a 4Fe-4S iron-sulfur cluster via bis-L-cysteinyl-L-N3'-histidino-L-serinyl tetrairon tetrasulfide. GO:0018305 iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-serinyl tetrairon tetrasulfide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018305 RESID:AA0288 iron incorporation into iron-sulphur cluster via tris-L-cysteinyl-L-serinyl tetrairon tetrasulphide The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-serinyl tetrairon tetrasulfide. GO:0018300 obsolete iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl hexairon hexasulfide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018300 iron incorporation into iron-sulphur cluster via hexakis-L-cysteinyl hexairon hexasulphide|iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl hexairon hexasulfide OBSOLETE. The incorporation of iron into a 6Fe-6S cluster by hexakis-L-cysteinyl hexairon hexasulfide. GO:0033941 mannan exo-1,2-1,6-alpha-mannosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033941 MetaCyc:3.2.1.137-RXN|EC:3.2.1.137 exo-1,2-1,6-alpha-mannosidase activity|1,2-1,6-alpha-D-mannan D-mannohydrolase activity Catalysis of the hydrolysis of (1->2)-alpha-D- and (1->6)-alpha-D- linkages in mannan, releasing D-mannose. GO:0033940 glucuronoarabinoxylan endo-1,4-beta-xylanase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033940 MetaCyc:3.2.1.136-RXN|EC:3.2.1.136 glucuronoxylan xylohydrolase activity|glucuronoarabinoxylan 1,4-beta-D-xylanohydrolase activity|glucuronoxylan xylanohydrolase activity|feraxan endoxylanase activity|glucuronoxylanase activity|feraxanase activity|endoarabinoxylanase activity Catalysis of the endohydrolysis of (1->4)-beta-D-xylosyl links in some glucuronoarabinoxylans. GO:0018302 iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-N1'-histidino tetrairon tetrasulfide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018302 RESID:AA0284 iron incorporation into iron-sulphur cluster via tris-L-cysteinyl-L-N1'-histidino tetrairon tetrasulphide The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-N1'-histidino tetrairon tetrasulfide. GO:0018301 iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-cysteine persulfido-bis-L-glutamato-L-histidino tetrairon biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018301 RESID:AA0268 iron incorporation into iron-sulphur cluster via tris-L-cysteinyl-L-cysteine persulphido-bis-L-glutamato-L-histidino tetrairon The incorporation of iron into an iron-sulfur cluster by tris-L-cysteinyl-L-cysteine persulfido-bis-L-glutamato-L-histidino tetrairon. CHEBI:58799 (2S)-2-{[(1R)-1-carboxylatoethyl]azaniumyl}pentanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58799 CHEBI:58798 N-(6-aminohexanoyl)-6-aminohexanoic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58798 CHEBI:2076 5-hydroxykynurenine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_2076 CHEBI:58797 (S,S)-9,10-dihydroxyoctadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58797 CHEBI:58796 (9S,10S)-10-hydroxy-9-(phosphonatooxy)octadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58796 CHEBI:58795 1-hydroxy-5-(methylthio)-3-oxopent-1-en-2-olate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58795 GO:0033938 1,6-alpha-L-fucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033938 MetaCyc:3.2.1.127-RXN|EC:3.2.1.127 1,6-L-fucosyl-N-acetyl-D-glucosaminylglycopeptide fucohydrolase activity Catalysis of the hydrolysis of (1->6) linkages between alpha-L-fucose and N-acetyl-D-glucosamine in glycopeptides such as immunoglobulin G glycopeptide and fucosyl-asialo-agalacto-fetuin. GO:0033937 3-deoxy-2-octulosonidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033937 EC:3.2.1.124|MetaCyc:3.2.1.124-RXN octulofuranosylono hydrolase activity|octulosylono hydrolase activity|octulopyranosylonohydrolase activity|2-keto-3-deoxyoctonate hydrolase activity|capsular-polysaccharide 3-deoxy-D-manno-2-octulosonohydrolase activity Catalysis of the endohydrolysis of the beta-ketopyranosidic linkages of 3-deoxy-D-manno-2-octulosonate in capsular polysaccharides. GO:0033936 polymannuronate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033936 EC:3.2.1.121|MetaCyc:3.2.1.121-RXN polymannuronic acid polymerase activity|poly(mannuronide) mannuronohydrolase activity Catalysis of the endohydrolysis of the D-mannuronide linkages of polymannuronate. GO:0033935 oligoxyloglucan beta-glycosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033935 EC:3.2.1.120|MetaCyc:3.2.1.120-RXN oligoxyloglucan xyloglucohydrolase activity|oligoxyloglucan hydrolase activity|isoprimeverose-producing oligoxyloglucan hydrolase activity Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic links in oligoxyloglucans so as to remove successive isoprimeverose (i.e. alpha-xylo-1,6-beta-D-glucosyl-) residues from the non-reducing chain ends. GO:0033934 glucan 1,4-alpha-maltotriohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033934 MetaCyc:3.2.1.116-RXN|EC:3.2.1.116 1,4-alpha-D-glucan maltotriohydrolase activity|maltotriohydrolase activity|exo-maltotriohydrolase activity Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltotriose residues from the non-reducing chain ends. GO:0008999 ribosomal-protein-alanine N-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008999 RHEA:43756|MetaCyc:2.3.1.128-RXN|EC:2.3.1.128 acetyl-CoA:ribosomal-protein-L-alanine N-acetyltransferase activity|ribosomal protein S18 acetyltransferase activity Catalysis of the reaction: acetyl-CoA + ribosomal-protein L-alanine = CoA + ribosomal-protein N-acetyl-L-alanine. GO:0033933 branched-dextran exo-1,2-alpha-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033933 MetaCyc:3.2.1.115-RXN|EC:3.2.1.115 dextran alpha-1,2 debranching enzyme|dextran 1,2-alpha-glucosidase activity|1,2-alpha-D-glucosyl-branched-dextran 2-glucohydrolase activity Catalysis of the hydrolysis of (1->2)-alpha-D-glucosidic linkages at the branch points of dextrans and related polysaccharides, producing free D-glucose. GO:0008998 ribonucleoside-triphosphate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008998 RHEA:12701|EC:1.17.4.2|MetaCyc:1.17.4.2-RXN 2'-deoxyribonucleoside-triphosphate:oxidized-thioredoxin 2'-oxidoreductase activity|2'-deoxyribonucleoside-triphosphate:thioredoxin-disulfide 2'-oxidoreductase activity|ribonucleotide reductase activity Catalysis of the reaction: 2'-deoxyribonucleoside triphosphate + thioredoxin disulfide + H2O = ribonucleoside triphosphate + thioredoxin. GO:0033932 1,3-alpha-L-fucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033932 EC:3.2.1.111|MetaCyc:3.2.1.111-RXN 3-alpha-L-fucosyl-N-acetylglucosaminyl-glycoprotein fucohydrolase activity|almond emulsin fucosidase I activity Catalysis of the hydrolysis of (1->3) linkages between alpha-L-fucose and N-acetylglucosamine residues in glycoproteins. GO:0008997 ribonuclease R activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008997 EC:3.1.11.- Catalysis of the reaction: RNA + H2O = 5'-phosphomononucleotides. Cleaves RNA in the 3' to 5' direction, leaving an undigested core of 3-5 nucleotides. GO:0033931 endogalactosaminidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033931 MetaCyc:3.2.1.109-RXN|EC:3.2.1.109 galactosaminoglycan glycanohydrolase activity Catalysis of the endohydrolysis of (1->4)-alpha-D-galactosaminidic linkages in poly(D-galactosamine). GO:0008996 ribonuclease G activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008996 Catalysis of the cleavage of single-stranded RNA that is monophosphorylated at its 5'-end; cleavage occurs predominantly at positions 5 and 6 nucleotides from the 5'-end and in A + U-rich regions, and is blocked by the presence of a 5'-triphosphate group. GO:0008995 ribonuclease E activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008995 MetaCyc:3.1.26.12-RXN Catalysis of the cleavage of single-stranded RNA that is monophosphorylated at its 5'-end; cleavage occurs predominantly at 5 nucleotides from the 5'-end and in A + U-rich regions, and is blocked by the presence of a 5'-triphosphate group. GO:0008994 rhamnulose-1-phosphate aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008994 MetaCyc:RHAMNULPALDOL-RXN|RHEA:19689|EC:4.1.2.19 L-rhamnulose 1-phosphate aldolase activity|rhamnulose phosphate aldolase activity|L-rhamnulose-1-phosphate S-lactaldehyde-lyase (glycerone-phosphate-forming)|L-rhamnulose-1-phosphate lactaldehyde-lyase activity|L-rhamnulose-phosphate aldolase activity Catalysis of the reaction: L-rhamnulose 1-phosphate = glycerone phosphate + (S)-lactaldehyde. OBO:GOCHE_35222 substance with inhibitor role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_35222 GO:0008993 rhamnulokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008993 RHEA:20117|MetaCyc:RHAMNULOKIN-RXN|EC:2.7.1.5 RhuK|L-rhamnulose kinase activity|rhamnulose kinase activity|ATP:L-rhamnulose 1-phosphotransferase activity|L-rhamnulokinase activity|rhamnulokinase (phosphorylating) Catalysis of the reaction: ATP + L-rhamnulose = ADP + L-rhamnulose 1-phosphate. CHEBI:44147 menaquinone-9 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_44147 OBO:GOCHE_35221 substance with antimetabolite role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_35221 GO:0008992 obsolete repressor LexA activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008992 LexA repressor|repressor lexA|repressor LexA activity OBSOLETE. Catalysis of the hydrolysis of Ala-Gly bond in repressor lexA. GO:0008991 obsolete serine-type signal peptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008991 serine-type signal peptidase activity OBSOLETE. Catalysis of the cleavage of a signal peptide from a protein precursor by a serine endopeptidase mechanism. GO:0008990 rRNA (guanine-N2-)-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008990 MetaCyc:RRNA-GUANINE-N2--METHYLTRANSFERASE-RXN|EC:2.1.1.52 S-adenosyl-L-methionine:rRNA (guanine-2-N-)-methyltransferase activity|S-adenosyl-L-methionine:rRNA (guanine-N2-)-methyltransferase activity|ribosomal ribonucleate guanine-2-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N2-methylguanine. GO:0033939 xylan alpha-1,2-glucuronosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033939 MetaCyc:3.2.1.131-RXN|EC:3.2.1.131 xylan alpha-D-1,2-(4-O-methyl)glucuronohydrolase activity|alpha-(1->2)-glucuronidase activity|1,2-alpha-glucuronidase activity Catalysis of the hydrolysis of alpha-D-(1->2)-(4-O-methyl)glucuronosyl links in the main chain of hardwood xylans. CHEBI:58783 2-hydroxy-3-methylacyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58783 GO:0018319 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018319 GO:0018318 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018318 CHEBI:58782 D-dopachrome(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58782 CHEBI:58781 (4R)-2-acetyl-4-(3-acetyl-2,4,6-trihydroxy-5-methylphenyl)-4-methyl-3-oxocyclohexa-1,5-dien-1-olate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58781 PR:000030035 G-protein coupled receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000030035 seven-transmembrane receptor|7TM receptor|fam:GPCR A protein that has G protein-coupled receptor (GPCR) activity. Each GPCR consists of a single polypeptide with an extracellular N-terminus, an intracellular C-terminus and seven hydrophobic transmembrane domains (TM1-TM7) linked by three extracellular loops (ECL1-ECL3) and three intracellular loops (ICL1-ICL3). GPCRs function as part of a heterotrimeric complex to transmit an extracellular signal across the membrane by activating an associated G-protein via the exchange of GDP for GTP on the alpha subunit. CHEBI:58780 2,6-dihydroxynicotinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58780 GO:0018315 molybdenum incorporation into molybdenum-molybdopterin complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018315 molybdenum incorporation into metallo-pterin complex The incorporation of molybdenum into a molybdenum-molybdopterin complex. GO:0018314 obsolete protein-pyrroloquinoline-quinone linkage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018314 protein-pyrroloquinoline-quinone linkage OBSOLETE. The covalent cross-linking of pyrroloquinoline-quinone to peptidyl-glutamic acid and peptidyl-tyrosine. GO:0018317 protein C-linked glycosylation via tryptophan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018317 protein amino acid C-linked glycosylation via tryptophan The glycosylation of a carbon atom of a peptidyl-tryptophan residue. GO:0018316 peptide cross-linking via L-cystine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018316 RESID:AA0025 The oxidation of two peptidyl-cysteine residues to form a peptidyl-L-cystine (dicysteine) in which segments of peptide chain are linked by a disulfide bond; the cross-link may be between different or the same peptide chain. GO:0018311 peptidyl-N4-hydroxymethyl-L-asparagine biosynthetic process from peptidyl-asparagine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018311 RESID:AA0236 peptidyl-N4-hydroxymethyl-L-asparagine formation from peptidyl-asparagine|peptidyl-N4-hydroxymethyl-L-asparagine synthesis from peptidyl-asparagine|peptidyl-N4-hydroxymethyl-L-asparagine anabolism from peptidyl-asparagine The chemical reactions and pathways resulting in the formation of N4-hydroxymethyl-L-asparagine from other compounds, including peptidyl-asparagine. GO:0033930 keratan-sulfate endo-1,4-beta-galactosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033930 MetaCyc:3.2.1.103-RXN|EC:3.2.1.103 endo-beta-galactosidase activity|keratanase activity|keratan-sulfate 1,4-beta-D-galactanohydrolase activity|keratan sulfate endogalactosidase activity Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in keratan sulfate. CHEBI:2082 5-hydroxyxanthotoxin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_2082 GO:0018310 protein-FMN linkage via S-(6-FMN)-L-cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018310 RESID:AA0220 The formation of a protein-FMN linkage via S-(6-FMN)-L-cysteine. GO:0018313 peptide cross-linking via L-alanyl-5-imidazolinone glycine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018313 RESID:AA0187 The formation of a protein active site cross-link from the alpha-carboxyl carbon of residue N, an alanine, to the alpha-amino nitrogen of residue N+2, a glycine, coupled with the formation of a double bond to the alpha-amino nitrogen of residue N+1 which loses one hydrogen, and the loss of a molecule of water. GO:0018312 peptidyl-serine ADP-ribosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018312 RESID:AA0237 The transfer, from NAD, of ADP-ribose to peptidyl-serine to form peptidyl-O-(ADP-ribosyl)-L-serine. CHEBI:58787 cis-3,4-didehydroadipoyl-CoA semialdehyde(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58787 CHEBI:58786 cis-3,4-didehydroadipoyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58786 CHEBI:58785 2,3-dihydroxy-2,3-dihydrobenzoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58785 CHEBI:58784 2-hydroxy-3-methylhexadecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58784 CHEBI:83739 ferroheme c di-L-cysteine(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83739 GO:0102232 acrolein reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102232 MetaCyc:RXN-12281 Catalysis of the reaction: acrolein + NADPH + H+ <=> propanal + NADP. CHEBI:83738 3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1,5-dioxo-octahydroinden-4-yl]propanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83738 GO:0102234 but-1-en-3-one reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102234 MetaCyc:RXN-12293 Catalysis of the reaction: buten-2-one + NADPH + H+ <=> butan-2-one + NADP. CHEBI:83736 3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1,5-dioxo-octahydroinden-4-yl]propanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83736 GO:0102233 crotonaldehyde redutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102233 MetaCyc:RXN-12292 Catalysis of the reaction: (cis)-crotonaldehyde + NADPH + H+ <=> butanal + NADP. GO:0102236 trans-4-hexen-3-one reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102236 MetaCyc:RXN-12296 Catalysis of the reaction: trans-4-hexen-3-one + NADPH + H+ <=> hexan-3-one + NADP. GO:0102235 1-penten-3-one reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102235 MetaCyc:RXN-12295 Catalysis of the reaction: 1-penten-3-one + NADPH + H+ <=> 1-pentan-3-one + NADP. GO:0102238 geraniol kinase activity (ATP-dependent) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102238 MetaCyc:RXN-12307 Catalysis of the reaction: geraniol + ATP = geranyl monophosphate + ADP + H+. GO:0102237 ATP-dependent farnesol kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102237 MetaCyc:RXN-12304 Catalysis of the reaction: (2-trans,6-trans)-farnesol + ATP(4-) <=> H+ + 2-trans,-6-trans-farnesyl monophosphate + ADP(3-). PR:000019642 dystroglycan proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000019642 DAG1/ClvPrd A dystroglycan that has been processed by proteolytic cleavage. GO:0102241 soyasaponin III rhamnosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102241 RHEA:31491|EC:2.4.1.273|MetaCyc:RXN-12320 Catalysis of the reaction: UDP-L-rhamnose + soyasaponin III <=> H+ + UDP + soyasaponin I. GO:0102240 soyasapogenol B glucuronide galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102240 RHEA:31487|MetaCyc:RXN-12319|EC:2.4.1.272 Catalysis of the reaction: UDP-D-galactose + soyasapogenol B 3-O-beta-glucuronate <=> H+ + UDP + soyasaponin III. GO:0102243 ATP:geranylgeraniol phosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102243 RHEA:61660|EC:2.7.1.216|MetaCyc:RXN-12325 Catalysis of the reaction: (E,E)-geranylgeraniol + ATP = H+ + all-trans-geranyl-geranyl monophosphate + ADP. GO:0102245 lupan-3beta,20-diol synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102245 RHEA:31351|EC:4.2.1.128|MetaCyc:RXN-12338 Catalysis of the reaction: lupan-3beta,20-diol <=> (S)-2,3-epoxysqualene + H2O. CHEBI:83746 3-ketocholest-4-en-26-al biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83746 GO:0102244 3-aminopropanal dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102244 MetaCyc:RXN-12332 Catalysis of the reaction: 3-ammoniopropanal + NAD + H2O <=> 2 H+ + beta-alanine + NADH. GO:0102247 malonyl-malonyl acyl carrier protein-condensing enzyme activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102247 MetaCyc:RXN-12361 Catalysis of the reaction: 2 H+ + 2 a malonyl-[acp] <=> 2 carbon dioxide + an acetoacetyl-[acp] + a holo-[acyl-carrier protein]. CHEBI:83745 validamycins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83745 GO:0102246 6-amino-6-deoxyfutalosine hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102246 EC:3.2.2.30|RHEA:33079|MetaCyc:RXN-12346 Catalysis of the reaction: aminodeoxyfutalosinate + H2O <=> dehypoxanthine futalosine + adenine. GO:0102249 phosphatidylcholine:diacylglycerol cholinephosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102249 MetaCyc:RXN-12386 Catalysis of the reaction: a phosphatidylcholine + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycerol + a phosphatidylcholine. GO:0102248 diacylglycerol transacylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102248 MetaCyc:RXN-12383 Catalysis of the reaction: 2 a 1,2-diacyl-sn-glycerol = a triacyl-sn-glycerol + a 2-monoglyceride. CHEBI:138290 2-hydroxyoctanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138290 GO:0102250 linear malto-oligosaccharide phosphorylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102250 EC:2.4.1.1|MetaCyc:RXN-12392 Catalysis of the reaction: hydrogenphosphate + a linear malto-oligosaccharide = alpha-D-glucose 1-phosphate + a linear malto-oligosaccharide. GO:0102252 cellulose 1,4-beta-cellobiosidase activity (reducing end) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102252 EC:3.2.1.176|MetaCyc:RXN-12420 Catalysis of the reaction: n H2O + a cellodextrin = n beta-cellobiose, releasing cellobiose from the reducing ends of the chains. CHEBI:138294 N(epsilon)-(5'-guanylyl)-L-lysine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138294 GO:0102251 all-trans-beta-apo-10'-carotenal cleavage oxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102251 MetaCyc:RXN-12393|EC:1.13.11.70|RHEA:26401 Catalysis of the reaction: 10'-apo-beta-carotenal + O2 <=> 13-apo-beta-carotenone + 4-methylocta-2,4,6-trienedial. CHEBI:138293 bis(hydroperoxy)icosatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138293 GO:0102254 neoagarotetraose 1,3-alpha-3,6-anhydro-L-galactosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102254 EC:3.2.1.159|MetaCyc:RXN-12427 Catalysis of the reaction: neoagarotetraose + H2O <=> 3,6-anhydro-alpha-L-galactopyranose + agarotriose. CHEBI:138292 2-hydroxydecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138292 GO:0102253 neoagarobiose 1,3-alpha-3,6-anhydro-L-galactosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102253 EC:3.2.1.159|MetaCyc:RXN-12426 Catalysis of the reaction: neoagarobiose + H2O <=> 3,6-anhydro-alpha-L-galactopyranose + beta-D-galactoside. CHEBI:138291 (5S,15S)-dihydroperoxy-(6E,8Z,11Z,13E)-icosatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138291 GO:0102256 neoagarohexaose 1,3-alpha-3,6-anhydro-L-galactosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102256 EC:3.2.1.159|MetaCyc:RXN-12429 Catalysis of the reaction: neoagarohexaose + H2O <=> 3,6-anhydro-alpha-L-galactopyranose + agaropentaose. CHEBI:83757 EC 2.4.1.231 [alpha,alpha-trehalose phosphorylase (configuration-retaining)] inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83757 GO:0102255 neo-lambda-carrahexaose hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102255 MetaCyc:RXN-12428|EC:3.2.1.162 Catalysis of the reaction: neo-lambda-carrahexaose + H2O <=> neo-lambda-carratetraose + neo-lambda-carrabiose. GO:0102258 1,3-diacylglycerol acylhydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102258 MetaCyc:RXN-12433 Catalysis of the reaction: H2O + a 1,3-diglyceride = a monoglyceride + a fatty acid. GO:0102257 1-16:0-2-18:2-phosphatidylcholine sn-1 acylhydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102257 MetaCyc:RXN-12430 Catalysis of the reaction: 1-palmitoyl-2-linoleoyl-phosphatidylcholine + H2O <=> 1-linoleoyl-sn-glycero-3-phosphocholine + hexadecanoate + H+. GO:0102259 1,2-diacylglycerol acylhydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102259 MetaCyc:RXN-12434 Catalysis of the reaction: H2O + a 1,2-diacyl-sn-glycerol = a monoglyceride + a fatty acid. CHEBI:138286 N-terminal N,N-dimethyl-L-alanyl-L-prolyl-L-lysyl(2+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138286 CHEBI:138284 5'-end ribonucleoside residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138284 CHEBI:138288 5'-end purine ribonucleotide 5'-triphosphate(4-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138288 GO:0102261 8-hydroxy-5-deazaflavin:NADPH oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102261 EC:1.5.1.40|RHEA:31363|MetaCyc:RXN-12450 Catalysis of the reaction: NADP + a reduced coenzyme F420 <=> NADPH + H+ + an oxidized coenzyme F420. GO:0102260 germacrene A alcohol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102260 RHEA:30667|EC:1.1.1.314|MetaCyc:RXN-12449 Catalysis of the reaction: germacra-1(10),4,11(13)-trien-12-ol + 2 NADP + H2O <=> germacra-1(10),4,11(13)-trien-12-oate + 2 NADPH + 3 H+. GO:0102263 tRNA-dihydrouridine17 synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102263 EC:1.3.1.88|MetaCyc:RXN-12455 Catalysis of the reaction: a 5,6-dihydrouracil17 in tRNA + NAD(P) <=> H+ + a uracil17 in tRNA + NAD(P)H. GO:0102262 tRNA-dihydrouridine16 synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102262 MetaCyc:RXN-12454 Catalysis of the reaction: a 5,6-dihydrouracil16 in tRNA + NAD(P) <=> H+ + a uracil16 in tRNA + NAD(P)H. GO:0102265 tRNA-dihydrouridine47 synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102265 EC:1.3.1.89|MetaCyc:RXN-12457 Catalysis of the reaction: a 5,6-dihydrouracil47 in tRNA + NAD(P) <=> H+ + a uracil47 in tRNA + NAD(P)H. GO:0102264 tRNA-dihydrouridine20 synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102264 EC:1.3.1.91|MetaCyc:RXN-12456 Catalysis of the reaction: a 5,6-dihydrouracil20 in tRNA + NAD(P) <=> H+ + a uracil20 in tRNA + NAD(P)H. GO:0102267 tRNA-dihydrouridine20b synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102267 MetaCyc:RXN-12476 Catalysis of the reaction: a 5,6-dihydrouracil20b in tRNA + NAD(P) <=> H+ + a uracil20b in tRNA + NAD(P)H. GO:0102266 tRNA-dihydrouridine20a synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102266 EC:1.3.1.90|MetaCyc:RXN-12475 Catalysis of the reaction: a 5,6-dihydrouracil20a in tRNA + NAD(P) <=> H+ + a uracil20a in tRNA + NAD(P)H. CHEBI:83767 2''-O-acetyl-ADP-D-ribose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83767 CHEBI:83762 EC 3.2.1.28 (alpha,alpha-trehalase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83762 CHEBI:83760 EC 2.4.1.64 (alpha,alpha-trehalose phosphorylase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83760 PO:0005352 xylem biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0005352 木質部 (Japanese, exact)|portion of xylem tissue (exact)|xilema (Spanish, exact) A portion of vascular tissue (PO:0009015) that has as part one or more tracheary elements (PO:0000290). CHEBI:138298 2-hydroxyicosanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138298 CHEBI:138297 2-hydroxyheptadecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138297 CHEBI:138296 2-hydroxyisovaleryl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138296 CHEBI:138295 (5S,6R)-dihydroxy-(7E,9E,11Z,14Z)-icosatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138295 CHEBI:138299 2-hydroxydodecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138299 CHEBI:138272 8,9-epoxy-20-hydroxy-(5Z,11Z,14Z)-icosatrienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138272 CHEBI:138270 12,13-epoxy-18-hydroxy-(9Z)-octadecenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138270 CHEBI:83778 1,2-di[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83778 CHEBI:83777 3-oxo-23,24-bisnorchol-4-en-22-oate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83777 CHEBI:83776 3-oxo-23,24-bisnorchol-4-en-22-oic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83776 CHEBI:83775 1,2-dioleoyl-sn-glycerol-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83775 CHEBI:83774 1,2-dioctadecanoyl-sn-glycerol-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83774 CHEBI:138265 9,10-epoxy-18-hydroxy-(12Z)-octadecenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138265 CHEBI:138262 (9S,10R)-epoxyoctadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138262 CHEBI:138269 1-O-hexadecyl-2-(8-carboxyoctanoyl)-sn-glycero-3-phosphocholine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138269 CHEBI:138268 D-xylulose 1,5-bisphosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138268 CHEBI:138267 hexanoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138267 CHEBI:138266 2-heptanoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138266 CHEBI:138282 5'-end ribonucleotide(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138282 CHEBI:138281 16-oxoresolvin D2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138281 CHEBI:138280 adenosine-5'-diphospho-5'-ribonucleotide(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138280 GO:0102201 (+)-2-epi-prezizaene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102201 MetaCyc:RXN-12117 Catalysis of the reaction: 2-cis,6-trans-farnesyl diphosphate <=> (+)-2-epi-prezizaene + diphosphoric acid. GO:0043300 regulation of leukocyte degranulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043300 regulation of immune cell degranulation|regulation of immune cell granule exocytosis|regulation of leukocyte granule exocytosis|regulation of leucocyte degranulation Any process that modulates the frequency, rate, or extent of leukocyte degranulation. GO:0102200 N-acetylphosphatidylethanolamine-hydrolysing phospholipase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102200 MetaCyc:RXN-12116|EC:3.1.4.54|RHEA:33159 Catalysis of the reaction: H2O + an N-acylphosphatidylethanolamine = H+ + an N-acylethanolamine + a 1,2-diacyl-sn-glycerol 3-phosphate. GO:0102203 brassicasterol glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102203 EC:2.4.1.173|MetaCyc:RXN-12125|RHEA:61840 Catalysis of the reaction: UDP-alpha-D-glucose + brassicasterol <=> UDP(3-) + 3-O-beta-D-glucosyl-brassicasterol + H+. GO:0043302 positive regulation of leukocyte degranulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043302 positive regulation of leucocyte degranulation|up regulation of leukocyte degranulation|activation of leukocyte degranulation|stimulation of leukocyte degranulation|positive regulation of immune cell degranulation|up-regulation of leukocyte degranulation|upregulation of leukocyte degranulation Any process that activates or increases the frequency, rate or extent of leukocyte degranulation. GO:0043301 negative regulation of leukocyte degranulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043301 down regulation of leukocyte degranulation|downregulation of leukocyte degranulation|negative regulation of leucocyte degranulation|down-regulation of leukocyte degranulation|inhibition of leukocyte degranulation|negative regulation of immune cell degranulation Any process that stops, prevents, or reduces the rate of leukocyte degranulation. GO:0102202 soladodine glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102202 EC:2.4.1.173|MetaCyc:RXN-12123|RHEA:61844 Catalysis of the reaction: UDP-alpha-D-glucose + solasodine <=> UDP + solasodine 3-O-beta-D-glucopyranoside + H+. GO:0102205 cholesterol alpha-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102205 EC:2.4.1.173|MetaCyc:RXN-12127|RHEA:61848 cholesterol UDP-glucosyltransferase activity|cholesterol allpha-glucosyltransferase activity Catalysis of the reaction: UDP-alpha-D-glucose + cholesterol = UDP + cholesteryl beta-D-glucoside + H+. GO:0102207 docosanoate omega-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102207 MetaCyc:RXN-12155|RHEA:40079 behenate omega-hydroxylase activity Catalysis of the reaction: docosanoate + O2 + reduced [NADPH--hemoprotein reductase] = 22-hydroxydocosanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]. CHEBI:83785 1-palmitoyl-2-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83785 CHEBI:83783 (25S)-3beta-hydroxy-5-cholesten-26-oyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83783 GO:0043308 eosinophil degranulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043308 eosinophil granule exocytosis The regulated exocytosis of secretory granules containing preformed mediators such as major basic protein, eosinophil peroxidase, and eosinophil cationic protein by an eosinophil. GO:0102209 trans-permethrin hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102209 MetaCyc:RXN-12167|EC:3.1.1.88|RHEA:30283 Catalysis of the reaction: (-)-trans-permethrin + H2O <=> H+ + (3-phenoxyphenyl)methanol + (1S,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate. GO:0043307 eosinophil activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043307 The change in morphology and behavior of a eosinophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. GO:0102208 2-polyprenyl-6-hydroxyphenol methylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102208 MetaCyc:RXN-12160|RHEA:31411 Catalysis of the reaction: S-adenosyl-L-methionine + a 3-(all-trans-polyrenyl)benzene-1,2-diol <=> S-adenosyl-L-homocysteine + H+ + a 2-methoxy-6-(all-trans-polyprenyl)phenol. GO:0043309 regulation of eosinophil degranulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043309 regulation of eosinophil granule exocytosis Any process that modulates the frequency, rate, or extent of eosinophil degranulation. GO:0043304 regulation of mast cell degranulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043304 regulation of mast cell granule exocytosis Any process that modulates the frequency, rate, or extent of mast cell degranulation. GO:0043303 mast cell degranulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043303 mast cell granule exocytosis The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell. GO:0043306 positive regulation of mast cell degranulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043306 up regulation of mast cell degranulation|activation of mast cell degranulation|stimulation of mast cell degranulation|up-regulation of mast cell degranulation|positive regulation of mast cell granule exocytosis|upregulation of mast cell degranulation Any process that activates or increases the frequency, rate or extent of mast cell degranulation. GO:0043305 negative regulation of mast cell degranulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043305 downregulation of mast cell degranulation|down-regulation of mast cell degranulation|inhibition of mast cell degranulation|negative regulation of mast cell granule exocytosis|down regulation of mast cell degranulation Any process that stops, prevents, or reduces the rate of mast cell degranulation. CHEBI:138276 5'-end purine ribonucleoside 5'-diphosphate(3-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138276 CHEBI:138275 oxidized Renilla luciferin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138275 CHEBI:138274 14,15-epoxy-20-hydroxy-(5Z,8Z,11Z)-icosatrienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138274 CHEBI:138273 11,12-epoxy-20-hydroxy-(5Z,8Z,14Z)-icosatrienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138273 CHEBI:138279 7-oxoresolvin D2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138279 CHEBI:138278 5'-end GTP-ribonucleotide(5-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138278 GO:0018391 C-terminal peptidyl-glutamic acid tyrosinylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018391 The ATP-dependent addition of a tyrosine residue to a glutamic acid residue at the C-terminus of a protein. GO:0018390 peptidyl-L-glutamic acid 5-methyl ester biosynthetic process from peptidyl-glutamic acid or peptidyl-glutamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018390 RESID:AA0072 peptidyl-L-glutamic acid 5-methyl ester anabolism from peptidyl-glutamic acid or peptidyl-glutamine|peptidyl-L-glutamic acid 5-methyl ester synthesis from peptidyl-glutamic acid or peptidyl-glutamine|peptidyl-L-glutamic acid 5-methyl ester formation from peptidyl-glutamic acid or peptidyl-glutamine The methyl esterification of peptidyl-glutamic acid or peptidyl-glutamine to form the derivative glutamic acid 5-methyl ester. GO:0018393 internal peptidyl-lysine acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018393 The addition of an acetyl group to a non-terminal lysine residue in a protein. GO:0018392 glycoprotein 3-alpha-L-fucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018392 MetaCyc:2.4.1.214-RXN|RHEA:24444|KEGG_REACTION:R06015|EC:2.4.1.214 GDP-L-fucose:glycoprotein (L-fucose to asparagine-linked N-acetylglucosamine of 4-N-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}asparagine) 3-alpha-L-fucosyl-transferase activity|GDP-fucose:beta-N-acetylglucosamine (Fuc to (Fuc-alpha-1->6-GlcNAc)-Asn-peptide) alpha-1->3-fucosyltransferase activity|GDP-fucose:beta-N-acetylglucosamine (Fuc to (Fucalpha1->6-GlcNAc)-Asn-peptide) alpha1->3-fucosyltransferase activity|GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,3-fucosyltransferase activity|GDP-L-Fuc:Asn-linked GlcNAc alpha1,3-fucosyltransferase activity|GDP-fucose:beta-N-acetylglucosamine (Fuc to (Fucalpha1->6GlcNAc)-Asn-peptide) alpha1->3-fucosyltransferase activity|GDP-L-fucose:asparagine-linked N-acetylglucosamine alpha(1,3)-fucosyltransferase activity|GDP-L-Fuc:Asn-linked GlcNAc alpha-1,3-fucosyltransferase activity|GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha-1,3-fucosyltransferase activity|GDP-L-fucose:glycoprotein (L-fucose to asparagine-linked N-acetylglucosamine of N4-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}asparagine) 3-alpha-L-fucosyl-transferase activity Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP-L-fucose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP + H(+). GO:0102210 rhamnogalacturonan endolyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102210 MetaCyc:RXN-12173|EC:4.2.2.23 Catalysis of the reaction: H2O + a rhamnogalacturonan type I <=> [rhamnogalacturonan I oligosaccharide]-alpha-L-rhamnose + 4-deoxy-4,5-unsaturated D-galactopyranosyluronate-[rhamnogalacturonan I oligosaccharide]. GO:0043311 positive regulation of eosinophil degranulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043311 stimulation of eosinophil degranulation|up-regulation of eosinophil degranulation|activation of eosinophil degranulation|positive regulation of eosinophil granule exocytosis|up regulation of eosinophil degranulation|upregulation of eosinophil degranulation Any process that activates or increases the frequency, rate or extent of eosinophil degranulation. GO:0102212 unsaturated chondroitin disaccharide hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102212 MetaCyc:RXN-12177|EC:3.2.1.180|RHEA:31647 Catalysis of the reaction: beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GalpNAc6S + H2O = 5-dehydro-4-deoxy-D-glucuronate + N-acetyl-beta-D-galactosamine 6-sulfate. GO:0102211 unsaturated rhamnogalacturonyl hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102211 EC:3.2.1.172|RHEA:30927|MetaCyc:RXN-12174 Catalysis of the reaction: 2-O-(4-deoxy-beta-L-threo-hex-4-enopyranuronosyl)-alpha-L-rhamnopyranose(1-) + H2O <=> (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + alpha-L-rhamnopyranose. GO:0043310 negative regulation of eosinophil degranulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043310 negative regulation of eosinophil granule exocytosis|down-regulation of eosinophil degranulation|downregulation of eosinophil degranulation|down regulation of eosinophil degranulation|inhibition of eosinophil degranulation Any process that stops, prevents, or reduces the rate of eosinophil degranulation. GO:0102214 omega-hydroxy fatty acyl-CoA synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102214 MetaCyc:RXN-12185 Catalysis of the reaction: coenzyme A + ATP + an omega-hydroxy fatty acid = diphosphoric acid + AMP + a omega-hydroxyacyl-CoA. GO:0043313 regulation of neutrophil degranulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043313 regulation of neutrophil granule exocytosis Any process that modulates the frequency, rate, or extent of neutrophil degranulation. GO:0043312 neutrophil degranulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043312 heterophil degranulation|neutrophil granule exocytosis The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil. GO:0102213 in-chain hydroxy fatty acyl-CoA synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102213 MetaCyc:RXN-12184 Catalysis of the reaction: coenzyme A + ATP + an in-chain hydroxy fatty acid = diphosphoric acid + AMP + a in-chain hydroxyacyl-CoA. GO:0102216 maltodextrin water dikinase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102216 EC:2.7.9.4|MetaCyc:RXN-12201 Catalysis of the reaction: ATP + H2O + a maltodextrin = AMP + hydrogenphosphate + a 6-phosphogluco-maltodextrin. CHEBI:83798 N-hexanoylsphingosine 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83798 GO:0102215 thiocyanate methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102215 RHEA:28014|MetaCyc:RXN-12189 Catalysis of the reaction: thiocyanate + S-adenosyl-L-methionine <=> methyl thiocyanate + S-adenosyl-L-homocysteine. CHEBI:83797 3-hydroxy-9-oxo-9,10-seco-23,24-bisnorchola-1,3,5(10)-trien-22-oate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83797 GO:0102218 starch, H2O dikinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102218 EC:2.7.9.4|MetaCyc:RXN-12203 Catalysis of the reaction: n ATP + n H2O + starch = n AMP + n hydrogenphosphate + a 6-phosphogluco-amylopectin. CHEBI:83796 3-hydroxy-9-oxo-9,10-seco-23,24-bisnorchola-1,3,5(10)-trien-22-oic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83796 CHEBI:83795 3-oxodotriacontanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83795 GO:0102217 6-phosphoglucan, water dikinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102217 RHEA:10256|MetaCyc:RXN-12202|EC:2.7.9.5 Catalysis of the reaction: n ATP + n H2O + a 6-phosphogluco-maltodextrin = n AMP + n hydrogenphosphate + a poly-6-phosphogluco-maltodextrin. GO:0043319 positive regulation of cytotoxic T cell degranulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043319 positive regulation of cytotoxic T-cell granule exocytosis|up regulation of cytotoxic T cell degranulation|positive regulation of cytotoxic T lymphocyte degranulation|positive regulation of cytotoxic T lymphocyte granule exocytosis|upregulation of cytotoxic T cell degranulation|positive regulation of cytotoxic T cell granule exocytosis|stimulation of cytotoxic T cell degranulation|positive regulation of cytotoxic T-cell degranulation|activation of cytotoxic T cell degranulation|up-regulation of cytotoxic T cell degranulation|positive regulation of cytotoxic T-lymphocyte degranulation|positive regulation of cytotoxic T-lymphocyte granule exocytosis Any process that activates or increases the frequency, rate or extent of cytotoxic T cell degranulation. CHEBI:83794 3-hydroxy-9-oxo-9,10-seco-23,24-bisnorchola-1,3,5(10)-trien-22-oyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83794 GO:0102219 phosphogluco-amylopectin water dikinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102219 EC:2.7.9.5|MetaCyc:RXN-12204 Catalysis of the reaction: n ATP + n H2O + a 6-phosphogluco-amylopectin = n AMP + n hydrogenphosphate + a 6-phosphogluco-3-phosphogluco-amylopectin. GO:0043318 negative regulation of cytotoxic T cell degranulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043318 down-regulation of cytotoxic T cell degranulation|negative regulation of cytotoxic T-lymphocyte granule exocytosis|negative regulation of cytotoxic T-cell granule exocytosis|negative regulation of cytotoxic T lymphocyte degranulation|downregulation of cytotoxic T cell degranulation|down regulation of cytotoxic T cell degranulation|inhibition of cytotoxic T cell degranulation|negative regulation of cytotoxic T lymphocyte granule exocytosis|negative regulation of cytotoxic T-cell degranulation|negative regulation of cytotoxic T-lymphocyte degranulation|negative regulation of cytotoxic T cell granule exocytosis Any process that stops, prevents, or reduces the rate of cytotoxic T cell degranulation. CHEBI:83793 3-oxo-23,24-bisnorchola-1,4-dien-22-oyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83793 CHEBI:83792 3-oxo-23,24-bisnorchol-4-en-22-oyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83792 GO:0043315 positive regulation of neutrophil degranulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043315 up regulation of neutrophil degranulation|upregulation of neutrophil degranulation|stimulation of neutrophil degranulation|up-regulation of neutrophil degranulation|activation of neutrophil degranulation|positive regulation of neutrophil granule exocytosis Any process that activates or increases the frequency, rate or extent of neutrophil degranulation. GO:0043314 negative regulation of neutrophil degranulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043314 downregulation of neutrophil degranulation|down regulation of neutrophil degranulation|inhibition of neutrophil degranulation|down-regulation of neutrophil degranulation|negative regulation of neutrophil granule exocytosis Any process that stops, prevents, or reduces the rate of neutrophil degranulation. GO:0043317 regulation of cytotoxic T cell degranulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043317 regulation of cytotoxic T-cell degranulation|regulation of cytotoxic T-lymphocyte degranulation|regulation of cytotoxic T lymphocyte granule exocytosis|regulation of cytotoxic T cell granule exocytosis|regulation of cytotoxic T lymphocyte degranulation|regulation of cytotoxic T-lymphocyte granule exocytosis|regulation of cytotoxic T-cell granule exocytosis Any process that modulates the frequency, rate, or extent of cytotoxic T cell degranulation. GO:0043316 cytotoxic T cell degranulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043316 cytotoxic T lymphocyte degranulation|cytotoxic T-lymphocyte granule exocytosis|cytotoxic T-cell granule exocytosis|cytotoxic T-cell degranulation|cytotoxic T-lymphocyte degranulation|cytotoxic T lymphocyte granule exocytosis|cytotoxic T cell granule exocytosis The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a cytotoxic T cell. GO:0018388 N-terminal peptidyl-valine condensation with pyruvate to form N-pyruvic acid 2-iminyl-L-valine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018388 RESID:AA0275 The condensation of pyruvate through the 2-oxo group with the N-terminal valine of proteins to form the derivative N-pyruvic acid 2-iminyl-L-valine. GO:0018387 N-terminal peptidyl-amino acid deamination to pyruvic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018387 RESID:AA0127 The oxidative deamination of N-terminal peptidyl-cysteine, or peptidyl-serine, to form pyruvic acid with an amide bond between its 1-carboxyl group and the N-terminal residue. GO:0018389 N-terminal peptidyl-valine deamination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018389 The deamination of the N-terminal valine residue of a protein to form isobutyrate. GO:0018384 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018384 CHEBI:138247 cycloaraneosene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138247 GO:0018383 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018383 GO:0018386 N-terminal peptidyl-cysteine condensation with pyruvate to form N-pyruvic acid 2-iminyl-L-cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018386 RESID:AA0274 The condensation of pyruvate through the 2-oxo group with the N-terminal cysteine of proteins to form the derivative N-pyruvic acid 2-iminyl-L-cysteine. GO:0018385 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018385 CHEBI:138261 very long-chain fatty acyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138261 CHEBI:138260 (9R,10S)-9,10-epoxyoctadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138260 GO:0102220 hydrogenase activity (NAD+, ferredoxin) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102220 RHEA:30279|EC:1.12.1.4|MetaCyc:RXN-12215 Catalysis of the reaction: 2 dihydrogen + NAD + 2 an oxidized ferredoxin = NADH + 3 H+ + 2 a reduced ferredoxin. GO:0102223 4,4'-diapophytoene desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102223 MetaCyc:RXN-12224|EC:1.3.8.2|RHEA:31391 Catalysis of the reaction: 4 H+ + 15-cis-4,4'-diapophytoene + 4 FAD <=> 4,4'-diapolycopene + 4 FADH2. GO:0043322 negative regulation of natural killer cell degranulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043322 negative regulation of natural killer cell granule exocytosis|down regulation of natural killer cell degranulation|negative regulation of NK cell granule exocytosis|downregulation of natural killer cell degranulation|negative regulation of NK cell degranulation|down-regulation of natural killer cell degranulation|inhibition of natural killer cell degranulation Any process that stops, prevents, or reduces the rate of natural killer cell degranulation. GO:0043321 regulation of natural killer cell degranulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043321 regulation of NK cell degranulation|regulation of natural killer cell granule exocytosis|regulation of NK cell granule exocytosis Any process that modulates the frequency, rate, or extent of natural killer cell degranulation. GO:0102222 obsolete 6-phosophogluco-3-phosphogluco-starch phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102222 MetaCyc:RXN-12218 OBSOLETE. Catalysis of the reaction: m+q H2O + a 6-phosphogluco-3-phosphogluco-amylopectin <=> m+q hydrogenphosphate + a 6-phosphogluco-3-phosphogluco-amylopectin. GO:0102225 4,4'-diaponeurosporene desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102225 MetaCyc:RXN-12258|RHEA:31407 Catalysis of the reaction: 4,4'-diaponeurosporene + FAD + H+ <=> 4,4'-diapolycopene + FADH2. GO:0043324 pigment metabolic process involved in developmental pigmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043324 pigment metabolic process during developmental pigmentation|pigment metabolism during developmental pigmentation The chemical reactions and pathways involving biological pigments e.g. melanin, occurring as part of the development of an organ or organism. GO:0102224 GDP-2,4-diacetamido-2,4,6-trideoxy-alpha-D-glucopyranose hydrolase/2-epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102224 MetaCyc:RXN-12236|RHEA:46316 Catalysis of the reaction: GDP-2,4-diacetamido-2,4,6-trideoxy-alpha-D-glucopyranose + H2O <=> 2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose + GDP + H+. GO:0043323 positive regulation of natural killer cell degranulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043323 upregulation of natural killer cell degranulation|positive regulation of natural killer cell granule exocytosis|positive regulation of NK cell degranulation|positive regulation of NK cell granule exocytosis|up regulation of natural killer cell degranulation|activation of natural killer cell degranulation|stimulation of natural killer cell degranulation|up-regulation of natural killer cell degranulation Any process that activates or increases the frequency, rate or extent of natural killer cell degranulation. GO:0043320 natural killer cell degranulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043320 NK cell granule exocytosis|NK cell degranulation|natural killer cell granule exocytosis The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a natural killer cell. GO:0102229 amylopectin maltohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102229 MetaCyc:RXN-12278|EC:3.2.1.2 Catalysis of the reaction: n H2O + an exposed unphosphorylated, unbranched malto-oligosaccharide tail on amylopectin <=> amylopectin + maltose. GO:0043329 obsolete protein targeting to membrane involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043329 protein-membrane targeting during ubiquitin-dependent protein breakdown via the MVB pathway|protein-membrane targeting during ubiquitin-dependent protein catabolism via the MVB pathway|protein-membrane targeting during ubiquitin-dependent protein catabolic process via the MVB pathway|protein membrane targeting during ubiquitin-dependent protein catabolism via the MVB pathway|protein membrane targeting during ubiquitin-dependent protein catabolic process via the MVB pathway|protein targeting to membrane during ubiquitin-dependent protein degradation via the MVB pathway|protein-membrane targeting during ubiquitin-dependent protein degradation via the MVB pathway|protein targeting to membrane during ubiquitin-dependent protein catabolic process via the MVB pathway|protein targeting to membrane during ubiquitin-dependent protein breakdown via the MVB pathway OBSOLETE. The process of directing proteins towards a membrane using signals contained within the protein, occurring that contributes to ubiquitin-dependent protein catabolism via the MVB pathway; the destruction of a protein or peptide covalently tagged with a ubiquitin, via the multivesicular body (MVB) sorting pathway. GO:0043326 chemotaxis to folate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043326 The directed movement of a motile cell or organism in response to the presence of folate. GO:0043325 phosphatidylinositol-3,4-bisphosphate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043325 Interacting selectively and non-covalently with phosphatidylinositol-3,4-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' and 4' positions. GO:0043328 protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043328 protein targeting to vacuole during ubiquitin-dependent protein catabolic process via the MVB pathway|protein targeting to vacuole during ubiquitin-dependent protein breakdown via the MVB pathway|protein-vacuole targeting during ubiquitin-dependent protein catabolic process via the MVB pathway|protein vacuolar targeting during ubiquitin-dependent protein catabolic process via the MVB pathway|protein-vacuolar targeting during ubiquitin-dependent protein degradation via the MVB pathway|protein vacuolar targeting during ubiquitin-dependent protein catabolism via the MVB pathway|protein-vacuolar targeting during ubiquitin-dependent protein breakdown via the MVB pathway|protein-vacuole targeting during ubiquitin-dependent protein catabolism via the MVB pathway|protein targeting to vacuole during ubiquitin-dependent protein degradation via the MVB pathway The process of directing proteins towards the vacuole that contributes to protein catabolism via the multivesicular body (MVB) pathway. GO:0043327 chemotaxis to cAMP biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043327 chemotaxis to adenosine 3',5'-cyclophosphate|chemotaxis to cyclic AMP|chemotaxis to 3',5' cAMP|chemotaxis to 3',5'-cAMP The directed movement of a motile cell or organism in response to the presence of 3',5'-cAMP. GO:0018399 peptidyl-phenylalanine bromination to L-4'-bromophenylalanine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018399 RESID:AA0176 The bromination of peptidyl-phenylalanine to form L-4'-bromophenylalanine. GO:0018398 peptidyl-phenylalanine bromination to L-3'-bromophenylalanine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018398 RESID:AA0175 The bromination of peptidyl-phenylalanine to form L-3'-bromophenylalanine. GO:0018395 peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018395 RESID:AA0028 The hydroxylation of peptidyl-lysine to peptidyl-5-hydroxy-L-lysine. CHEBI:138258 (9R,10S)-9,10-epoxy-18-hydroxyoctadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138258 GO:0018394 peptidyl-lysine acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018394 The acetylation of peptidyl-lysine. GO:0018397 peptidyl-phenylalanine bromination to L-2'-bromophenylalanine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018397 RESID:AA0174 The bromination of peptidyl-phenylalanine to form L-2'-bromophenylalanine. CHEBI:138256 N-(4-oxoglutaryl)-L-cysteinylglycine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138256 GO:0018396 peptidyl-lysine hydroxylation to 4-hydroxy-L-lysine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018396 RESID:AA0235 The hydroxylation of peptidyl-lysine to peptidyl-4-hydroxy-L-lysine. CHEBI:138255 (9S,10R)-9,10-epoxy-18-hydroxyoctadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138255 PO:0005417 phloem biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0005417 portion of phloem tissue (exact)|floema (Spanish, exact)|師部、師管 (Japanese, exact) A portion of vascular tissue (PO:0009015) that has as parts sieve elements (PO:0025406). UBERON:0005594 head somite biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005594 occipital somite|cranial somite Somite located in the head region, caudal to the otic vesicle UBERON:0005590 rhombomere 8 roof plate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005590 roof plate rhombomere 8 A rhombomere roof plate that is part of a rhombomere 8. PO:0005421 parenchyma biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0005421 portion of parenchymatous tissue (exact)|parénquima (Spanish, exact)|portion of parenchyma tissue (exact)|柔組織 (Japanese, exact) A portion of ground tissue (PO:0025059) composed of polyhedral cells typically with thin, non-lignified cellulosic cell walls and nucleate, living protoplasts. UBERON:0005598 trunk somite biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005598 A somite that is part of a trunk. UBERON:0005597 lung primordium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005597 lung diverticulum|lateral diverticula|lung endoderm A pair of lateral diverticula just over the liver rudiment representing the primordia of the lungs, formed by the floor of the foregut just anterior to the liver diverticulum. UBERON:0005584 rhombomere 6 roof plate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005584 roof plate rhombomere 6 A rhombomere roof plate that is part of a rhombomere 6. UBERON:0005583 rhombomere 6 lateral wall biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005583 lateral wall rhombomere 6 A rhombomere lateral wall that is part of a rhombomere 6. UBERON:0005581 rhombomere 5 roof plate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005581 roof plate rhombomere 5 A rhombomere roof plate that is part of a rhombomere 5. UBERON:0005580 rhombomere 5 lateral wall biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005580 lateral wall rhombomere 5 A rhombomere lateral wall that is part of a rhombomere 5. UBERON:0005589 rhombomere 8 lateral wall biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005589 lateral wall rhombomere 8 A rhombomere lateral wall that is part of a rhombomere 8. UBERON:0005587 rhombomere 7 roof plate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005587 roof plate rhombomere 7 A rhombomere roof plate that is part of a rhombomere 7. UBERON:0005586 rhombomere 7 lateral wall biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005586 lateral wall rhombomere 7 A rhombomere lateral wall that is part of a rhombomere 7. UBERON:0005574 rhombomere 3 lateral wall biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005574 lateral wall rhombomere 3 A rhombomere lateral wall that is part of a rhombomere 3. UBERON:0005572 rhombomere 2 roof plate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005572 roof plate rhombomere 2 A rhombomere roof plate that is part of a rhombomere 2. UBERON:0005571 rhombomere 2 lateral wall biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005571 lateral wall rhombomere 2 A rhombomere lateral wall that is part of a rhombomere 2. UBERON:0005578 rhombomere 4 roof plate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005578 roof plate rhombomere 4 A rhombomere roof plate that is part of a rhombomere 4. UBERON:0005577 rhombomere 4 lateral wall biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005577 lateral wall rhombomere 4 A rhombomere lateral wall that is part of a rhombomere 4. UBERON:0005575 rhombomere 3 roof plate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005575 roof plate rhombomere 3 A rhombomere roof plate that is part of a rhombomere 3. CHEBI:34718 1-chloro-2,4-dinitrobenzene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_34718 UBERON:0005563 trigeminal neural crest biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005563 Cranial neural crest which gives rise to the trigeminal ganglion. UBERON:0005562 thymus primordium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005562 thymic primordium|thymic rudiment A small outgrowth of the pharyngeal epithelium that is the site of lymphocyte cell production[ZFA]. [PMID]. UBERON:0005569 rhombomere 2 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005569 r2 the second transiently divided segment of the developing rhombencephalon; rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates; rhombomeres are numbered in caudal to rostral order UBERON:0005568 rhombomere 1 roof plate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005568 roof plate rhombomere 1 A rhombomere roof plate that is part of a rhombomere 1. UBERON:0005567 rhombomere 1 lateral wall biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005567 lateral wall rhombomere 1 A rhombomere lateral wall that is part of a rhombomere 1. UBERON:0005565 facio-acoustic neural crest biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005565 facio acoustic neural crest Cranial neural crest that gives rise to the facio-acoustic ganglion. UBERON:0005564 gonad primordium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005564 gonadal primordium|immature gonad|primitive gonad|future gonad|undifferentiated gonad Portion of tissue that gives rise to the immature gonad. GO:0102272 homophytochelatin synthase activity (polymer-forming) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102272 MetaCyc:RXN-12528 Catalysis of the reaction: glutathionate + a poly gamma-glutamylcysteine-beta-alanine = glycine + a poly gamma-glutamylcysteine-beta-alanine. GO:0102274 glutathione S-conjugate carboxypeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102274 MetaCyc:RXN-12532 Catalysis of the reaction: H2O + a glutathione-toxin conjugate <=> glycine + a [Glu-Cys]-S-conjugate. GO:0102273 homophytochelatin synthase (dimmer forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102273 MetaCyc:RXN-12529 Catalysis of the reaction: glutathionate + L-gamma-glutamyl-L-cysteinyl-beta-alaninate <=> gamma-Glu-Cys-gamma-Glu-Cys-beta-Ala + glycine. GO:0102276 2-oxoglutarate oxygenase/decarboxylase (ethylene-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102276 EC:1.13.12.19|MetaCyc:RXN-12538|RHEA:31523 Catalysis of the reaction: 2-oxoglutarate(2-) + O2 + 2 H+ <=> ethene + 3 carbon dioxide + H2O. GO:0102275 cysteine-S-conjugate N-malonyl transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102275 MetaCyc:RXN-12534 Catalysis of the reaction: malonyl-CoA(5-) + an L-cysteine-S-conjugate <=> coenzyme A + H+ + an N-malonyl-L-cysteine-S-conjugate. GO:0102278 N,N'-diacetylchitobiose synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102278 MetaCyc:RXN-12554 Catalysis of the reaction: n H2O + chitin <=> N,N'-diacetylchitobiose. GO:0102277 2-acetamido-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-D-glucose exo-beta-D-glucosaminidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102277 MetaCyc:RXN-12544 Catalysis of the reaction: 2-acetamido-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-D-glucose + H2O = N-acetyl-D-glucosamine + D-glucosamine. GO:0102279 lecithin:11-cis retinol acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102279 EC:2.3.1.135|MetaCyc:RXN-12563 Catalysis of the reaction: an 11-cis retinol-[cellular-retinol-binding-protein] + a phosphatidylcholine <=> a cellular-retinol-binding protein + an 11-cis-retinyl ester + a 1-lysophosphatidylcholine. GO:0102281 formylaminopyrimidine deformylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102281 MetaCyc:RXN-12612 Catalysis of the reaction: formylaminopyrimidine + H2O <=> 4-amino-5-ammoniomethyl-2-methylpyrimidine + formate. GO:0102280 choline monooxygenase activity (NADP-dependent) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102280 MetaCyc:RXN-12582 Catalysis of the reaction: choline + NADP = betaine aldehyde + NADPH + H+. GO:0102283 3-ketodihydrosphinganine (C20) reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102283 MetaCyc:RXN-12642 Catalysis of the reaction: C20 sphinganine(1+) + NADP <=> C20 3-dehydrosphinganine(1+) + NADPH + H+. GO:0102282 3-ketodihydrosphinganine (C18) reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102282 MetaCyc:RXN-12641 Catalysis of the reaction: NAD(1-) + a sphinganine <=> 3-dehydrosphinganinium(1+) + NADH + H+. GO:0102285 1-deoxy-11-oxopentalenate oxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102285 EC:1.14.13.170|RHEA:34635|MetaCyc:RXN-12654 Catalysis of the reaction: 1-deoxy-11-oxopentalenate + O2 + NADPH + H+ = pentalenolactone D + H2O + NADP. GO:0102284 L-threo-sphinganine reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102284 MetaCyc:RXN-12645 Catalysis of the reaction: L-threo-sphinganine + NADP <=> H+ + NADPH + 3-dehydrosphinganinium(1+). GO:0102287 4-coumaroylhexanoylmethane synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102287 MetaCyc:RXN-12668 Catalysis of the reaction: 4-coumaryl-CoA + 3-oxooctanoyl-CoA + H2O <=> 4-coumaroylhexanoylmethane + 2 coenzyme A + carbon dioxide. GO:0102286 ornithine N-delta-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102286 MetaCyc:RXN-12667 Catalysis of the reaction: L-ornithinium(1+) = N(5)-acetyl-L-ornithine. GO:0102289 beta-amyrin 11-oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102289 RHEA:31711|MetaCyc:RXN-12680|EC:1.14.14.152 Catalysis of the reaction: beta-amyrin + 2 O2 + 2 NADPH + 2 H+ <=> 11-oxo-beta-amyrin + 3 H2O + 2 NADP. GO:0102290 beta-amyrin monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102290 MetaCyc:RXN-12681|RHEA:31715|EC:1.14.14.152 Catalysis of the reaction: beta-amyrin + O2 + NADPH + H+ <=> 11alpha-hydroxy-beta-amyrin + H2O + NADP. GO:0102292 30-hydroxy-beta-amyrin 11-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102292 MetaCyc:RXN-12683 Catalysis of the reaction: 30-hydroxy-beta-amyrin + O2 + NADPH + H+ <=> 11alpha,30-dihydroxy-beta-amyrin + H2O + NADP. GO:0102291 11alpha-hydroxy-beta-amyrin dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102291 RHEA:31719|MetaCyc:RXN-12682|EC:1.14.14.152 Catalysis of the reaction: 11alpha-hydroxy-beta-amyrin + O2 + NADPH + H+ = 11-oxo-beta-amyrin + 2 H2O + NADP. GO:0102294 cholesterol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102294 EC:1.1.1.145|MetaCyc:RXN-12693|RHEA:43932 Catalysis of the reaction: cholesterol + NAD = cholest-5-en-3-one + NADH + H+. GO:0102293 pheophytinase b activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102293 MetaCyc:RXN-12686|EC:3.1.1.14 Catalysis of the reaction: pheophytin b + H2O <=> H+ + pheophorbide b + phytol. CHEBI:83718 1,2-distearoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83718 GO:0102296 4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102296 EC:3.7.1.17|RHEA:32035|MetaCyc:RXN-12718 Catalysis of the reaction: (1E,2Z)-3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate + H2O <=> 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oate + (2Z,4Z)-2-hydroxyhexa-2,4-dienoate + H+. CHEBI:83717 1,2-dipalmitoleoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83717 GO:0102295 4-methylumbelliferyl glucoside 6'-O-malonyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102295 MetaCyc:RXN-12699 Catalysis of the reaction: 4-methylumbelliferyl glucoside + malonyl-CoA <=> 4-methylumbelliferone 6'-O-malonylglucoside + coenzyme A. CHEBI:83716 2-aminophenylglyoxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83716 GO:0102298 selenocystathione synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102298 MetaCyc:RXN-12728 Catalysis of the reaction: L-selenocysteine + O-phosphonato-L-homoserine = hydrogenphosphate + L-selenocystathionine. GO:0102297 selenate adenylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102297 MetaCyc:RXN-12720 Catalysis of the reaction: selenic acid + ATP + 2 H+ <=> adenylyl selenate + diphosphoric acid. CHEBI:83714 1,2,2'-trilinoleoyl-1'-monolysocardiolipin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83714 GO:0102299 linolenate 9R-lipoxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102299 EC:1.13.11.61|RHEA:31687|MetaCyc:RXN-12759 Catalysis of the reaction: alpha-linolenate + O2 <=> (9R,10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoate. PO:0005426 chlorenchyma biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0005426 portion of chlorenchyma tissue (exact)|clorénquima (Spanish, exact)|同化組織、葉緑組織 (Japanese, exact) Chloroplast-containing parenchyma tissue. PO:0005423 collenchyma biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0005423 colénquima (Spanish, exact)|厚角組織 (Japanese, exact)|portion of collenchyma tissue (exact)|supporting tissue (related) A portion of ground tissue (PO:0025059) which comprises living tissue composed of more or less elongated cells with thick, non-lignified primary cell walls. CHEBI:83728 very long-chain 2,3-trans-enoyl CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83728 CHEBI:83727 long-chain 2,3-trans-enoyl CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83727 CHEBI:83726 medium-chain 2,3-trans-enoyl CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83726 CHEBI:83725 primary alkymercury(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83725 CHEBI:83724 very long-chain 3-substituted propanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83724 CHEBI:83723 medium-chain 3-substituted propanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83723 CHEBI:10723 trans-dec-2-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_10723 CHEBI:83721 long-chain 3-substituted propanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83721 GO:0033927 glucan 1,4-alpha-maltohexaosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033927 EC:3.2.1.98|MetaCyc:3.2.1.98-RXN G6-amylase activity|maltohexaose-producing amylase activity|1,4-alpha-D-glucan maltohexaohydrolase activity|exo-maltohexaohydrolase activity Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltohexaose residues from the non-reducing chain ends. GO:0043292 contractile fiber biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043292 contractile fibre|muscle fibre|muscle fiber Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle. GO:0043291 RAVE complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043291 regulator of the (H+)-ATPase of the vacuolar and endosomal membranes A multisubunit complex that in Saccharomyces is composed of three subunits, Rav1p, Rav2p and Skp1p. Acts transiently to catalyze assembly of cytoplasmic V1, with membrane embedded V0 to form the V-ATPase holoenzyme. GO:0033926 glycopeptide alpha-N-acetylgalactosaminidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033926 EC:3.2.1.97|MetaCyc:3.2.1.97-RXN endo-alpha-acetylgalactosaminidase activity|D-galactosyl-N-acetyl-alpha-D-galactosamine D-galactosyl-N-acetyl-galactosaminohydrolase activity|endo-alpha-N-acetylgalactosaminidase activity Catalysis of the reaction: D-galactosyl-3-(N-acetyl-alpha-D-galactosaminyl)-L-serine + H2O = D-galactosyl-3-N-acetyl-alpha-D-galactosamine + L-serine in mucin-type glycoproteins. GO:0033925 mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033925 EC:3.2.1.96|Reactome:R-HSA-8853379|MetaCyc:3.2.1.96-RXN endoglycosidase H activity|endo-N-acetyl-beta-D-glucosaminidase activity|di-N-acetylchitobiosyl beta-N-acetylglucosaminidase activity|glycopeptide-D-mannosyl-4-N-(N-acetyl-D-glucosaminyl)2-asparagine 1,4-N-acetyl-beta-glucosaminohydrolase activity|endoglycosidase S activity|endo-N-acetyl-beta-glucosaminidase activity|endo-beta-acetylglucosaminidase activity|endo-beta-N-acetylglucosaminidase activity|endo-beta-N-acetylglucosaminidase D activity|endo-beta-N-acetylglucosaminidase F activity|endo-beta-N-acetylglucosaminidase H activity|N,N'-diacetylchitobiosyl beta-N-acetylglucosaminidase activity|endo-beta-(1->4)-N-acetylglucosaminidase activity|mannosyl-glycoprotein endo-beta-N-acetylglucosamidase activity|endo-beta-N-acetylglucosaminidase L activity|mannosyl-glycoprotein 1,4-N-acetamidodeoxy-beta-D-glycohydrolase activity|glycopeptide-D-mannosyl-N4-(N-acetyl-D-glucosaminyl)2-asparagine 1,4-N-acetyl-beta-glucosaminohydrolase activity Catalysis of the endohydrolysis of the N,N'-diacetylchitobiosyl unit in high-mannose glycopeptides and glycoproteins containing the -[Man(GlcNAc)2]Asn-structure. One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact. GO:0043294 mitochondrial glutamate synthase complex (NADH) biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043294 A protein complex, found in the mitochondria, that in yeast consists of a large and a small subunit. Possesses glutamate synthase (NADH) activity. GO:0008969 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008969 GO:0043293 apoptosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043293 Wikipedia:Apoptosome A multisubunit protein complex involved in the signaling phase of the apoptotic process. In mammals it is typically composed of seven Apaf-1 subunits bound to cytochrome c and caspase-9. A similar complex to promote apoptosis is formed from homologous gene products in other eukaryotic organisms. GO:0008968 D-sedoheptulose 7-phosphate isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008968 RHEA:27489|MetaCyc:RXN0-4301 phosphoheptose isomerase activity Catalysis of the reaction: D-sedoheptulose-7-phosphate = D-alpha,beta-D-heptose 7-phosphate. GO:0033924 dextran 1,6-alpha-isomaltotriosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033924 EC:3.2.1.95|MetaCyc:3.2.1.95-RXN 1,6-alpha-D-glucan isomaltotriohydrolase activity|exo-isomaltotriohydrolase activity Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in dextrans, to remove successive isomaltotriose units from the non-reducing ends of the chains. GO:0033923 glucan 1,6-alpha-isomaltosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033923 EC:3.2.1.94|MetaCyc:3.2.1.94-RXN isomaltodextranase activity|isomalto-dextranase activity|1,6-alpha-D-glucan isomaltohydrolase activity|G2-dextranase activity|exo-isomaltohydrolase activity Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in polysaccharides, to remove successive isomaltose units from the non-reducing ends of the chains. GO:0008967 phosphoglycolate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008967 MetaCyc:GPH-RXN|EC:3.1.3.18|KEGG_REACTION:R01334|RHEA:14369 phosphoglycolate hydrolase activity|2-phosphoglycolate phosphatase activity|P-glycolate phosphatase activity|2-phosphoglycolate phosphohydrolase activity|phosphoglycollate phosphatase activity Catalysis of the reaction: 2-phosphoglycolate + H(2)O = glycolate + phosphate. GO:0033922 peptidoglycan beta-N-acetylmuramidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033922 EC:3.2.1.92|MetaCyc:3.2.1.92-RXN peptidoglycan beta-N-acetylmuramoylexohydrolase activity|exo-beta-N-acetylmuramidase activity|exo-beta-acetylmuramidase activity|beta-2-acetamido-3-O-(D-1-carboxyethyl)-2-deoxy-D-glucoside acetamidodeoxyglucohydrolase activity Catalysis of the hydrolysis of terminal, non-reducing N-acetylmuramic residues. GO:0008966 phosphoglucosamine mutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008966 KEGG_REACTION:R02060|MetaCyc:5.4.2.10-RXN|RHEA:23424|EC:5.4.2.10 alpha-D-glucosamine 1,6-phosphomutase activity|D-glucosamine 1,6-phosphomutase activity Catalysis of the reaction: alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. GO:0008965 phosphoenolpyruvate-protein phosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008965 RHEA:23880|MetaCyc:2.7.3.9-RXN|EC:2.7.3.9 enzyme I of the phosphotransferase system|phosphoenolpyruvate--protein phosphatase activity|phosphoenolpyruvate:protein-L-histidine Npi-phosphotransferase activity|phosphopyruvate--protein phosphotransferase activity|sugar--PEP phosphotransferase enzyme I activity|phosphoenolpyruvate sugar phosphotransferase enzyme I activity|phosphoenolpyruvate:protein-L-histidine N-pros-phosphotransferase activity|phosphopyruvate--protein factor phosphotransferase activity Catalysis of the reaction: phosphoenolpyruvate + protein L-histidine = pyruvate + protein N(pi)-phospho-L-histidine. GO:0043290 apocarotenoid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043290 apo carotenoid catabolic process|apocarotenoid degradation|apocarotenoid breakdown|apocarotenoid catabolism The chemical reactions and pathways resulting in the breakdown of apocarotenoids, a class of compounds derived from the oxidative cleavage of carotenoids, many of which are biologically important e.g. retinal and abscisic acid. GO:0033921 capsular-polysaccharide endo-1,3-alpha-galactosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033921 EC:3.2.1.87|MetaCyc:3.2.1.87-RXN polysaccharide depolymerase activity|capsular polysaccharide galactohydrolase activity|aerobacter-capsular-polysaccharide galactohydrolase activity Catalysis of the random hydrolysis of (1->3)-alpha-D-galactosidic linkages in Aerobacter aerogenes capsular polysaccharide. UBERON:0005507 rhombomere 3 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005507 r3 the third transiently divided segment of the developing rhombencephalon; rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates; rhombomeres are numbered in caudal to rostral order GO:0008964 phosphoenolpyruvate carboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008964 RHEA:28370|MetaCyc:PEPCARBOX-RXN|EC:4.1.1.31|KEGG_REACTION:R00345 PEP carboxylase activity|phosphate:oxaloacetate carboxy-lyase (phosphorylating)|PEPC|PEPCase activity|phosphoenolpyruvic carboxylase activity|phosphate:oxaloacetate carboxy-lyase (adding phosphate; phosphoenolpyruvate-forming)|phosphopyruvate (phosphate) carboxylase activity Catalysis of the reaction: phosphate + oxaloacetate = phosphoenolpyruvate + HCO3-. GO:0033920 6-phospho-beta-galactosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033920 EC:3.2.1.85|RHEA:24568|MetaCyc:6-PHOSPHO-BETA-GALACTOSIDASE-RXN phospho-beta-D-galactosidase activity|phospho-beta-galactosidase activity|6-phospho-beta-D-galactoside 6-phosphogalactohydrolase activity|6-phospho-beta-D-galactosidase activity|beta-D-phosphogalactoside galactohydrolase activity Catalysis of the reaction: a 6-phospho-beta-D-galactoside + H2O = 6-phospho-D-galactose + an alcohol. OBO:GOCHE_35195 substance with surfactant role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_35195 GO:0008963 phospho-N-acetylmuramoyl-pentapeptide-transferase activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0008963 EC:2.7.8.13|MetaCyc:RXN-8975|RHEA:21920 UDP-MurNAc-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala:C(55)-isoprenoid alcohol transferase activity|UDP-MurNAc-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala:C55-isoprenoid alcohol transferase activity|UDP-MurNAc-Ala-gammaDGlu-Lys-DAla-DAla:undecaprenylphosphate transferase activity|phospho-NAc-muramoyl-pentapeptide translocase (UMP) activity|phosphoacetylmuramoylpentapeptide translocase activity|phosphoacetylmuramoylpentapeptidetransferase activity|UDP-MurNAc-Ala-gamma-DGlu-Lys-DAla-DAla:undecaprenylphosphate transferase activity|UDP-MurAc(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala):undecaprenyl-phosphate phospho-N-acetylmuramoyl-pentapeptide-transferase activity|MraY transferase activity|phospho-N-acetylmuramoyl pentapeptide translocase activity|UDP-MurNAc-pentapeptide phosphotransferase activity|phospho-MurNAc-pentapeptide transferase activity Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + undecaprenyl phosphate = UMP + N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine-diphosphoundecaprenol. GO:0043299 leukocyte degranulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043299 immune cell degranulation|immune cell granule exocytosis|leucocyte degranulation|leukocyte granule exocytosis The regulated exocytosis of secretory granules by a leukocyte. GO:0008962 phosphatidylglycerophosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008962 MetaCyc:PGPPHOSPHA-RXN|Reactome:R-HSA-1483197|EC:3.1.3.27|RHEA:16725 PGP phosphatase activity|phosphatidylglycerol phosphate phosphatase activity|phosphatidylglycerol phosphatase activity|phosphatidylglycerophosphate phosphohydrolase activity Catalysis of the reaction: phosphatidylglycerophosphate + H2O = phosphatidylglycerol + phosphate. GO:0008961 phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008961 Catalysis of the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the prospective N-terminal cysteine residue in an unmodified prolipoprotein. GO:0008960 phosphatidylglycerol-membrane-oligosaccharide glycerophosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008960 EC:2.7.8.20|MetaCyc:PGLYCEROLTRANSI-RXN oligosaccharide glycerophosphotransferase activity|phosphoglycerol transferase activity|phosphoglycerol transferase I|phosphatidylglycerol:membrane-derived-oligosaccharide-D-glucose glycerophosphotransferase activity Catalysis of the reaction: phosphatidylglycerol + membrane-derived-oligosaccharide D-glucose = 1,2-diacyl-sn-glycerol + membrane-derived-oligosaccharide 6-(glycerophospho)-D-glucose. GO:0043296 apical junction complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043296 apical junction|apical cell junction complex A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in some invertebrates, such as Drosophila, is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability. GO:0043295 glutathione binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043295 Interacting selectively and non-covalently with glutathione; a tripeptide composed of the three amino acids cysteine, glutamic acid and glycine. GO:0043298 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043298 GO:0033929 blood-group-substance endo-1,4-beta-galactosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033929 MetaCyc:3.2.1.102-RXN|EC:3.2.1.102 endo-beta-galactosidase activity|blood-group-substance 1,4-beta-D-galactanohydrolase activity Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in blood group A and B substances. GO:0033928 mannan 1,4-mannobiosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033928 MetaCyc:3.2.1.100-RXN|EC:3.2.1.100 1,4-beta-D-mannan mannobiohydrolase activity|exo-beta-mannanase activity|exo-1,4-beta-mannobiohydrolase activity|mannan 1,4-beta-mannobiosidase activity Catalysis of the hydrolysis of (1->4)-beta-D-mannosidic linkages in (1->4)-beta-D-mannans, to remove successive mannobiose residues from the non-reducing chain ends. GO:0043297 apical junction assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043297 apical junction complex assembly The formation of an apical junction, a functional unit located near the cell apex at the points of contact between epithelial cells composed of the tight junction, the zonula adherens junction and the desmosomes, by the aggregation, arrangement and bonding together of its constituents. CHEBI:58772 L-methionine (S)-S-oxide zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58772 CHEBI:58771 (R)-2-(carboxylatomethyl)-5-oxo-2,5-dihydro-2-furoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58771 CHEBI:58770 N-acetyl-alpha-neuraminate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58770 CHEBI:58779 CDP-choline(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58779 UBERON:0005515 rhombomere 5 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005515 r5 the fifth transiently divided segment of the developing rhombencephalon; rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates; rhombomeres are numbered in caudal to rostral order CHEBI:58778 6-(2-azaniumyl-2-carboxylatoethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58778 CHEBI:58777 2-hydroxymethylglutarate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58777 CHEBI:19168 17-oxo steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19168 CHEBI:58776 2-formylglutarate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58776 CHEBI:58775 3-oxo-3-ureidopropanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58775 UBERON:0005511 rhombomere 4 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005511 r4 the fourth transiently divided segment of the developing rhombencephalon; rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates; rhombomeres are numbered in caudal to rostral order CHEBI:58774 3-dehydro-L-gulonate 6-phosphate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58774 CHEBI:58773 L-methionine (R)-S-oxide zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58773 CHEBI:44120 L-methionine (S)-S-oxide residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_44120 GO:0033916 beta-agarase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033916 EC:3.2.1.81 agarose 4-glycanohydrolase activity|agarose 3-glycanohydrolase activity|agarase activity|AgaB|AgaA Catalysis of the hydrolysis of (1->4)-beta-D-galactosidic linkages in agarose, giving the tetramer as the predominant product. GO:0033915 mannan 1,2-(1,3)-alpha-mannosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033915 MetaCyc:3.2.1.77-RXN|EC:3.2.1.77 exo-1,2-1,3-alpha-mannosidase activity|1,2-1,3-alpha-D-mannan mannohydrolase activity Catalysis of the hydrolysis of (1->2) and (1->3) linkages in mannan, releasing mannose. GO:0033914 xylan 1,3-beta-xylosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033914 MetaCyc:3.2.1.72-RXN|EC:3.2.1.72 exo-beta-1,3'-xylanase activity|1,3-beta-D-xylosidase, exo-1,3-beta-xylosidase activity|1,3-beta-D-xylan xylohydrolase activity|beta-1,3'-xylanase activity|exo-1,3-beta-xylosidase activity Catalysis of the hydrolysis of successive xylose residues from the non-reducing termini of (1->3)-beta-D-xylans. GO:0033913 glucan endo-1,2-beta-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033913 MetaCyc:3.2.1.71-RXN|EC:3.2.1.71 endo-(1->2)-beta-D-glucanase activity|beta-D-1,2-glucanase activity|1,2-beta-D-glucan glucanohydrolase activity|endo-1,2-beta-glucanase activity Catalysis of the random hydrolysis of (1->2)-glucosidic linkages in (1->2)-beta-D-glucans. GO:0008979 prophage integrase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008979 integrase activity involved in establishment of integrated proviral latency Catalysis of the integration of prophage DNA into a target DNA molecule, usually a bacterial chromosome, via a sequence-specific recombination event which involves the formation of an intasome, a DNA-protein-complex designed for site-specific recombination of the phage and host DNA. GO:0033912 2,6-beta-fructan 6-levanbiohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033912 MetaCyc:3.2.1.64-RXN|EC:3.2.1.64 levanbiose-producing levanase activity|2,6-beta-D-fructofuranan 6-(beta-D-fructosyl)-D-fructose-hydrolase activity|beta-2,6-fructan-6-levanbiohydrolase activity|2,6-beta-D-fructan 6-beta-D-fructofuranosylfructohydrolase activity|2,6-beta-D-fructan 6-levanbiohydrolase activity Catalysis of the hydrolysis of (2->6)-beta-D-fructofuranan, to remove successive disaccharide residues as levanbiose, i.e. 6-(beta-D-fructofuranosyl)-D-fructose, from the end of the chain. GO:0008978 obsolete prepilin peptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008978 prepilin peptidase activity OBSOLETE. Catalysis of the cleavage of a Gly-Phe bond to release an N-terminal, basic peptide of 5-8 residues from type IV prepilin, and then N-methylates the new N-terminal amino group, the methyl donor being S-adenosyl-L-methionine. GO:0033911 mycodextranase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033911 MetaCyc:3.2.1.61-RXN|EC:3.2.1.61 1,3-1,4-alpha-D-glucan 4-glucanohydrolase activity Catalysis of the endohydrolysis of 1,4-alpha-D-glucosidic linkages in alpha-D-glucans containing both 1,3- and 1,4-bonds. GO:0008977 prephenate dehydrogenase (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008977 KEGG_REACTION:R01728|MetaCyc:PREPHENATEDEHYDROG-RXN|EC:1.3.1.12|RHEA:13869 prephenate:NAD+ oxidoreductase (decarboxylating)|hydroxyphenylpyruvate synthase activity|chorismate mutase--prephenate dehydrogenase activity Catalysis of the reaction: NAD(+) + prephenate = (4-hydroxyphenyl)pyruvate + CO(2) + NADH. GO:0033910 glucan 1,4-alpha-maltotetraohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033910 MetaCyc:3.2.1.60-RXN|EC:3.2.1.60 G4-amylase activity|glucan 1,4-alpha-maltotetrahydrolase activity|exo-maltotetraohydrolase activity|1,4-alpha-D-glucan maltotetraohydrolase activity|maltotetraose-forming amylase activity Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltotetraose residues from the non-reducing chain ends. GO:0008976 polyphosphate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008976 MetaCyc:POLYPHOSPHATE-KINASE-RXN|EC:2.7.4.1|RHEA:19573 polyphosphoric acid kinase activity|ATP-polyphosphate phosphotransferase activity|ATP:polyphosphate phosphotransferase activity|polyphosphate polymerase activity Catalysis of the reaction: ATP + phosphate(n) = ADP + phosphate(n+1). GO:0008975 obsolete pitrilysin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008975 Escherichia coli metalloproteinase Pi|Escherichia coli protease III|pitrilysin activity|protease III activity|PTR|protease Pi activity|proteinase Pi OBSOLETE. Catalysis of the preferential cleavage of Tyr16-Leu17 and Phe25-Tyr26 bonds of oxidized insulin B chain. Also acts on other substrates of Molecular weight less than 7 kDa such as insulin and glucagon. GO:0008974 phosphoribulokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008974 MetaCyc:PHOSPHORIBULOKINASE-RXN|EC:2.7.1.19|KEGG_REACTION:R01523|RHEA:19365 PRuK|phosphoribulokinase (phosphorylating)|phosphopentokinase activity|PKK|5-phosphoribulose kinase activity|ribulose phosphate kinase activity|PRK|ribulose-5-phosphate kinase activity|ATP:D-ribulose-5-phosphate 1-phosphotransferase activity Catalysis of the reaction: D-ribulose 5-phosphate + ATP = D-ribulose 1,5-bisphosphate + ADP + 2 H(+). GO:0008973 phosphopentomutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008973 MetaCyc:PPENTOMUT-RXN|Reactome:R-HSA-8982667|EC:5.4.2.7|Reactome:R-HSA-6787329|RHEA:18793 deoxyribomutase activity|alpha-D-glucose-1,6-bisphosphate:deoxy-D-ribose-1-phosphate phosphotransferase activity|alpha-D-ribose 1,5-phosphomutase activity|phosphodeoxyribomutase activity|phosphoribomutase activity|deoxyribose phosphomutase activity|D-ribose 1,5-phosphomutase activity Catalysis of the reaction: D-ribose 1-phosphate = D-ribose 5-phosphate. GO:0008972 phosphomethylpyrimidine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008972 EC:2.7.4.7|RHEA:19893|MetaCyc:PYRIMSYN3-RXN ATP:4-amino-2-methyl-5-phosphomethylpyrimidine phosphotransferase activity|hydroxymethylpyrimidine phosphokinase activity Catalysis of the reaction: ATP + 4-amino-2-methyl-5-phosphomethylpyrimidine = ADP + 4-amino-2-methyl-5-diphosphomethylpyrimidine. GO:0008971 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008971 GO:0008970 phospholipase A1 activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0008970 EC:3.1.1.32|MetaCyc:PHOSPHOLIPASE-A1-RXN|Reactome:R-HSA-1482847|Reactome:R-HSA-5694485|Reactome:R-HSA-1482920|RHEA:18689|Reactome:R-HSA-1482932|Reactome:R-HSA-1482862|Reactome:R-HSA-1482827|Reactome:R-HSA-1482892|Reactome:R-HSA-1482828 phosphatidylcholine 1-acylhydrolase activity Catalysis of the reaction: phosphatidylcholine + H2O = 2-acylglycerophosphocholine + a carboxylate. GO:0033919 glucan 1,3-alpha-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033919 Reactome:R-HSA-532667|Reactome:R-HSA-9683663|Reactome:R-HSA-548890|MetaCyc:3.2.1.84-RXN|Reactome:R-HSA-9694364|EC:3.2.1.84 1,3-alpha-D-glucan 3-glucohydrolase activity|exo-1,3-alpha-glucanase activity|glucosidase II activity Catalysis of the hydrolysis of terminal (1->3)-alpha-D-glucosidic links in 1,3-alpha-D-glucans. GO:0033918 kappa-carrageenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033918 MetaCyc:3.2.1.83-RXN|EC:3.2.1.83 kappa-carrageenan 4-beta-D-glycanohydrolase (configuration-retaining) activity|kappa-carrageenan 4-beta-D-glycanohydrolase activity Catalysis of the endohydrolysis of 1,4-beta-D-linkages between D-galactose 4-sulfate and 3,6-anhydro-D-galactose in kappa-carrageenans. GO:0033917 exo-poly-alpha-galacturonosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033917 MetaCyc:3.2.1.82-RXN|EC:3.2.1.82|RHEA:56232 exopolygalacturonosidase activity|exopolygalacturanosidase activity Catalysis of the hydrolysis of pectic acid from the non-reducing end, releasing digalacturonate. GOREL:0012006 results_in_maintenance_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GOREL_0012006 GOREL:0012006 CHEBI:58761 L-2,4-diazaniumylbutyrate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58761 CHEBI:58760 demethylsulochrin(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58760 CHEBI:2106 5-[(E)-caffeoyl]shikimic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_2106 CHEBI:58769 (S)-1-piperideine-6-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58769 CHEBI:58768 (1R,6S)-1,6-dihydroxy-4-methylcyclohexa-2,4-diene-1-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58768 CHEBI:58767 N-acetyl-LL-2,6-diaminopimelate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58767 CHEBI:58766 4-O-phosphonato-D-erythronate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58766 UBERON:0005502 rhombomere roof plate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005502 roof plate hindbrain|future hindbrain roof plate|roof plate rhombomere|roof plate rhombomere region|roof plate rhombomeres UBERON:0005501 rhombomere lateral wall biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005501 future hindbrain lateral wall A neural tube lateral wall that is part of a rhombomere. CHEBI:58765 N-acetyl-L-citrullinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58765 CHEBI:58764 (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58764 CHEBI:58763 N-(3-carboxylatopropanoyl)-L-glutamate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58763 CHEBI:58762 7,8-dihydroneopterin 3'-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58762 GO:0033905 xylan endo-1,3-beta-xylosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033905 EC:3.2.1.32|MetaCyc:3.2.1.32-RXN endo-beta-1,3-xylanase activity|xylanase activity|1,3-beta-xylanase activity|1,3-beta-D-xylan xylanohydrolase activity|endo-1,3-xylanase activity|endo-1,3-beta-xylanase activity|beta-1,3-xylanase activity|1,3-xylanase activity Catalysis of the random hydrolysis of (1->3)-beta-D-glycosidic linkages in (1->3)-beta-D-xylans. GO:0008949 oxalyl-CoA decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008949 EC:4.1.1.8|RHEA:19333|KEGG_REACTION:R01908|MetaCyc:OXALYL-COA-DECARBOXYLASE-RXN oxalyl-CoA carboxy-lyase (formyl-CoA-forming)|oxalyl-CoA carboxy-lyase activity|oxalyl coenzyme A decarboxylase activity Catalysis of the reaction: H(+) + oxalyl-CoA = CO(2) + formyl-CoA. GO:0033904 dextranase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033904 EC:3.2.1.11|MetaCyc:3.2.1.11-RXN 1,6-alpha-D-glucan 6-glucanohydrolase activity|DL 2|dextran hydrolase activity|dextranase DL 2 activity|alpha-D-1,6-glucan-6-glucanohydrolase activity|endodextranase activity|endo-dextranase activity|alpha-1,6-glucan-6-glucanohydrolase activity Catalysis of the endohydrolysis of 1,6-alpha-D-glucosidic linkages in dextran. GO:0008948 oxaloacetate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008948 RHEA:15641|EC:4.1.1.112|EC:1.1.1.38|MetaCyc:OXALODECARB-RXN|Reactome:R-HSA-9012016|KEGG_REACTION:R00217|EC:1.1.1.40 oxalate beta-decarboxylase activity|oxalacetic acid decarboxylase activity|oxaloacetate carboxy-lyase (pyruvate-forming)|oxaloacetate carboxy-lyase activity|oxaloacetate beta-decarboxylase activity Catalysis of the reaction: oxaloacetate = pyruvate + CO2. GO:0008947 obsolete omptin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008947 omptin activity OBSOLETE. Catalysis of the preferential cleavage of Xaa-Yaa in which both Xaa and Yaa are Arg or Lys. GO:0033903 obsolete endo-1,3(4)-beta-glucanase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033903 MetaCyc:3.2.1.6-RXN|EC:3.2.1.6 laminaranase activity|endo-1,3-beta-D-glucanase activity|laminarinase activity|endo-beta-1,3-1,4-glucanase activity|beta-1,3-glucanase activity|endo-1,4-beta-glucanase activity|1,3-(1,3;1,4)-beta-D-glucan 3(4)-glucanohydrolase activity|endo-1,3-beta-glucanase activity|endo-1,3(4)-beta-glucanase activity|beta-1,3-1,4-glucanase activity|endo-beta-1,3(4)-glucanase activity|endo-1,3-1,4-beta-D-glucanase activity|endo-beta-1,3-glucanase IV activity|endo-beta-(1->3)-D-glucanase activity|endo-beta-(1,3)-D-glucanase activity OBSOLETE. Catalysis of the endohydrolysis of 1,3- or 1,4-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolysed is itself substituted at C-3. GO:0008946 oligonucleotidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008946 MetaCyc:3.1.13.3-RXN|EC:3.1.13.3 Catalysis of the exonucleolytic cleavage of oligonucleotides to yield nucleoside 5'-phosphates. GO:0033902 rRNA endonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033902 EC:3.1.27.10|MetaCyc:3.1.27.10-RXN alpha-sarcin Catalysis of the hydrolysis of the phosphodiester linkage between guanosine and adenosine residues at one specific position in 28S rRNA from rat ribosomes. GO:0033901 ribonuclease V activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033901 MetaCyc:3.1.27.8-RXN|EC:3.1.27.8 endoribonuclease V activity Catalysis of the hydrolysis of poly(A), forming oligoribonucleotides and ultimately 3'-AMP. GO:0008945 obsolete oligopeptidase B activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008945 oligopeptidase B activity|protease II activity|Escherichia coli alkaline proteinase II OBSOLETE. Catalysis of the hydrolysis of Arg-Xaa and Lys-Xaa bonds in oligopeptides, even when P1' residue is proline. GO:0033900 ribonuclease F activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033900 MetaCyc:3.1.27.7-RXN|EC:3.1.27.7 ribonuclease F (E. coli) activity|RNase F activity Catalysis of the endonucleolytic cleavage of RNA precursor into two, leaving 5'-hydroxy and 3'-phosphate groups. GO:0008944 obsolete oligopeptidase A activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008944 oligopeptidase A activity|68000-M signalpeptide hydrolase activity OBSOLETE. Catalysis of the hydrolysis of oligopeptides, with broad specificity. Gly or Ala commonly occur as P1 or P1' residues, but more distant residues are also important, as is shown by the fact that Z-Gly-Pro-Gly-Gly-Pro-Ala is cleaved at the Gly-Gly bond, but not Z-(Gly)5. GO:0008943 obsolete glyceraldehyde-3-phosphate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008943 glyceraldehyde-3-phosphate dehydrogenase activity OBSOLETE. Catalysis of the reactions: glyceraldehyde 3-phosphate + phosphate + NAD(P)+ = 3-phospho-D-glyceroyl-phosphate + NAD(P)H + H+, and glyceraldehyde 3-phosphate + H2O + NAD(P)+ = 3-phospho-D-glycerate + NAD(P)H + H+. GO:0008942 nitrite reductase [NAD(P)H] activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008942 EC:1.7.1.4|MetaCyc:NITRITREDUCT-RXN|KEGG_REACTION:R00789|KEGG_REACTION:R00787 nitrite reductase (reduced nicotinamide adenine dinucleotide (phosphate)) activity|NAD(P)H2:nitrite oxidoreductase activity|NAD(P)H:nitrite oxidoreductase activity|assimilatory nitrite reductase activity|NADPH-nitrite reductase activity|ammonium-hydroxide:NAD(P)+ oxidoreductase activity|nitrite reductase [NAD(P)H2]|NADH-nitrite oxidoreductase activity Catalysis of the reaction: ammonium hydroxide + 3 NAD(P)+ + H2O = nitrite + 3 NAD(P)H + 3 H+. CHEBI:58759 6-phosphonatooxy-D-gluconate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58759 GO:0008941 nitric oxide dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008941 Reactome:R-HSA-1222723|EC:1.14.12.17|Reactome:R-HSA-5340226|MetaCyc:R621-RXN nitric oxide,NAD(P)H:oxygen oxidoreductase activity|NOD activity Catalysis of the reaction: 2 NO + 2 O2 + NADPH + H+ = 2 nitrate + NADP+. GO:0008940 nitrate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008940 EC:1.7.99.4|MetaCyc:NITRATREDUCT-RXN|RHEA:21068 nitrite:acceptor oxidoreductase|nitrite:(acceptor) oxidoreductase|nitrate reductase (acceptor)|respiratory nitrate reductase activity Catalysis of the reaction: nitrite + acceptor = nitrate + reduced acceptor. GO:0033909 fucoidanase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033909 EC:3.2.1.44|MetaCyc:3.2.1.44-RXN poly(1,2-alpha-L-fucoside-4-sulfate) glycanohydrolase activity Catalysis of the endohydrolysis of 1,2-alpha-L-fucoside linkages in fucoidan without release of sulfate. GO:0033908 beta-L-rhamnosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033908 EC:3.2.1.43|MetaCyc:3.2.1.43-RXN beta-L-rhamnoside rhamnohydrolase activity Catalysis of the hydrolysis of terminal, non-reducing beta-L-rhamnose residues in beta-L-rhamnosides. GO:0033907 beta-D-fucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033907 EC:3.2.1.38|MetaCyc:3.2.1.38-RXN beta-D-fucoside fucohydrolase activity|beta-fucosidase activity Catalysis of the hydrolysis of terminal non-reducing beta-D-fucose residues in beta-D-fucosides. CHEBI:20140 3-methylquinoline biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_20140 CHEBI:44111 3-mercaptopropanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_44111 GO:0033906 hyaluronoglucuronidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033906 EC:3.2.1.36|MetaCyc:3.2.1.36-RXN glucuronoglucosaminoglycan hyaluronate lyase activity|hyaluronate 3-glycanohydrolase activity|hyaluronidase activity|orgelase activity Catalysis of the random hydrolysis of 1,3-linkages between beta-D-glucuronate and N-acetyl-D-glucosamine residues in hyaluronate. CHEBI:58750 (25R)-3alpha,7alpha-dihydroxy-5beta-cholestan-26-oate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58750 CHEBI:34784 hepoxilin B3 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_34784 CHEBI:34787 heptanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_34787 CHEBI:58758 S-(hydroxymethyl)glutathione(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58758 CHEBI:58757 (9Z,11E,13S,15Z)-13-hydroperoxyoctadeca-9,11,15-trienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58757 CHEBI:58756 2-trans,6-trans,10-trans-geranylgeranyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58756 CHEBI:58754 pGpG(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58754 CHEBI:58753 ADP-D-ribose 1''-phosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58753 CHEBI:58752 (25R)-3alpha,7alpha-dihydroxy-5beta-cholestan-26-oyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58752 GO:0008959 phosphate acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008959 MetaCyc:PHOSACETYLTRANS-RXN|EC:2.3.1.8|RHEA:19521 phosphotransacetylase activity|phosphoacylase activity|PTA|acetyl-CoA:phosphate acetyltransferase activity Catalysis of the reaction: acetyl-CoA + phosphate = CoA + acetyl phosphate. GO:0008958 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008958 GO:0008957 phenylacetaldehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008957 MetaCyc:PHENDEHYD-RXN|EC:1.2.1.39|UM-BBD_reactionID:r0035|RHEA:21392 phenylacetaldehyde:NAD+ oxidoreductase activity Catalysis of the reaction: phenylacetaldehyde + NAD+ + H2O = phenylacetate + NADH + H+. GO:0008956 obsolete peptidyl-dipeptidase Dcp activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008956 MetaCyc:3.4.15.5-RXN|EC:3.4.15.5 dipeptidyl carboxypeptidase activity|peptidyl-dipeptidase Dcp activity|dipeptidyl carboxypeptidase (Dcp) OBSOLETE. Catalysis of the hydrolysis of unblocked, C-terminal dipeptides from oligopeptides, with broad specificity. Does not hydrolyze bonds in which P1' is Pro, or both P1 and P1' are Gly. GO:0008955 peptidoglycan glycosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008955 MetaCyc:RXN0-5405|RHEA:23708|EC:2.4.1.129 peptidoglycan TGase activity|penicillin binding protein (3 or 1B) activity|undecaprenyldiphospho-N-acetyl-D-glucosaminyl-(1->4)-(N-acetyl-D-muramoylpentapeptide):undecaprenyldiphospho-(N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide) disaccharidetransferase activity|peptidoglycan transglycosylase activity|bactoprenyldiphospho-N-acetylmuramoyl-(N-acetyl-D-glucosaminyl)-pentapeptide:peptidoglycan N-acetylmuramoyl-N-acetyl-D-glucosaminyltransferase activity|PG-II activity Catalysis of the reaction: [GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-diphosphoundecaprenol + GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = [GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-diphosphoundecaprenol + undecaprenyl diphosphate. CHEBI:20156 3-oxo-Delta(1) steroid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_20156 GO:0008954 obsolete peptidoglycan synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008954 peptidoglycan synthetase activity OBSOLETE. (Was not defined before being made obsolete). CHEBI:58749 5-deoxy-alpha-D-ribose 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58749 GO:0008953 penicillin amidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008953 EC:3.5.1.11|MetaCyc:PENICILLIN-AMIDASE-RXN|RHEA:18693 penicillin amidohydrolase activity|penicillin acylase activity|benzylpenicillin acylase activity|alpha-acylamino-beta-lactam acylhydrolase activity|novozym 217|semacylase activity|palmitoleoyl [acyl-carrier protein]-dependent acyltransferase activity|ampicillin acylase activity Catalysis of the reaction: penicillin + H2O = a carboxylate + 6-aminopenicillanate. CHEBI:58748 N-iminiumylmethyl-L-aspartate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58748 GO:0008952 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008952 GO:0008951 palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008951 RHEA:44012|MetaCyc:PALMITOTRANS-RXN palmitoleoyl ACP-dependent acyltransferase activity Catalysis of the reaction: a palmitoleoyl-[acyl-carrier protein] + alpha-KDO-(2->4)-alpha-KDO-(2->6)-lipid IVA = KDO2-(palmitoleoyl)-lipid IVA + a holo-[acyl-carrier protein]. GO:0008950 obsolete p-aminobenzoate synthetase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008950 p-aminobenzoate synthetase OBSOLETE. (Was not defined before being made obsolete). CHEBI:58747 1D-myo-inositol 1,2,3,5,6-pentakisphosphate(10-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58747 CHEBI:58746 UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-mannuronate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58746 CHEBI:58745 UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58745 CHEBI:58744 3-(3,4-dihydroxyphenyl)propanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58744 CHEBI:58743 13(2)-carboxypyropheophorbide a(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58743 CHEBI:58742 pyropheophorbide a anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58742 CHEBI:58741 7(1)-hydroxychlorophyllide a(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58741 GO:0008927 mannonate dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008927 KEGG_REACTION:R05606|EC:4.2.1.8|RHEA:20097|MetaCyc:MANNONDEHYDRAT-RXN D-mannonate hydrolyase activity|altronate hydrolase activity|mannonic hydrolase activity|altronic hydro-lyase activity|D-mannonate hydro-lyase (2-dehydro-3-deoxy-D-gluconate-forming)|mannonate hydrolyase activity|D-mannonate hydro-lyase activity Catalysis of the reaction: D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H(2)O. GO:0008926 mannitol-1-phosphate 5-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008926 RHEA:19661|MetaCyc:MANNPDEHYDROG-RXN|EC:1.1.1.17 Catalysis of the reaction: D-mannitol 1-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+. GO:0008925 maltose O-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008925 RHEA:10456|MetaCyc:MALTACETYLTRAN-RXN|EC:2.3.1.79 acetyl-CoA:maltose O-acetyltransferase activity|maltose transacetylase activity Catalysis of the reaction: acetyl-CoA + maltose = CoA + acetyl-maltose. GO:0008924 malate dehydrogenase (quinone) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008924 RHEA:22556|EC:1.1.5.4|MetaCyc:MALATE-DEHYDROGENASE-ACCEPTOR-RXN (S)-malate:quinone oxidoreductase activity|(S)-malate:(quinone) oxidoreductase activity|FAD-dependent malate dehydrogenase activity|MQO activity Catalysis of the reaction: (S)-malate + a quinone = oxaloacetate + a quinol. GO:0008923 lysine decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008923 KEGG_REACTION:R00462|RHEA:22352|MetaCyc:LYSDECARBOX-RXN|EC:4.1.1.18|MetaCyc:PWY0-461 L-lysine carboxy-lyase activity|L-lysine carboxy-lyase (cadaverine-forming) Catalysis of the reaction: L-lysine + H(+) = cadaverine + CO(2). GO:0008922 long-chain fatty acid [acyl-carrier-protein] ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008922 RHEA:45588|EC:6.2.1.20|KEGG_REACTION:R07325|MetaCyc:ACYLACPSYNTH-RXN long-chain fatty acid-[acyl-carrier-protein] ligase activity|long-chain-fatty-acid-ACP ligase activity|acyl-[acyl-carrier-protein] synthetase activity|long-chain-fatty-acid-[acyl-carrier protein] ligase activity|long-chain-fatty-acid-acyl-carrier-protein ligase activity|acyl-ACP synthetase activity|acyl-acyl carrier protein synthetase|acyl-acyl-carrier-proteinsynthetase activity|acyl-acyl-carrier-protein synthetase activity|stearoyl-ACP synthetase activity|long-chain-fatty-acid-[acyl-carrier-protein] ligase activity|long-chain-fatty-acid:acyl-carrier-protein ligase (AMP-forming) activity Catalysis of the reaction: ATP + an acid + [acyl-carrier protein] = AMP + diphosphate + acyl-[acyl-carrier protein]. A long-chain fatty acid is fatty acid with a chain length between C13 and C22. CHEBI:58739 2-aminobut-2-enoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58739 GO:0008921 lipopolysaccharide-1,6-galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008921 LPS-1,6-galactosyltransferase activity Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,6 alpha-D-galactosyl-lipopolysaccharide. CHEBI:58738 (R)-3-sulfolactate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58738 GO:0008920 lipopolysaccharide heptosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008920 LPS heptosyltransferase activity Catalysis of the reaction: a lipopolysaccharide + ADP-L-glycero-beta-D-manno-heptose = a heptosylated lipopolysaccharide + ADP + H+. CHEBI:58737 (R)-2-O-sulfonatolactate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58737 CHEBI:34768 furfural biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_34768 OBO:GOCHE_50790 substance with EC 1.14.14.14 (aromatase) inhibitor role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_50790 CHEBI:19129 11alpha-hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19129 CHEBI:58736 (S)-5-oxo-2,5-dihydro-2-furylacetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58736 CHEBI:58735 D-mannopyranose 6-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58735 CHEBI:58734 (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58734 CHEBI:58733 4-methylene-L-glutamate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58733 CHEBI:58732 N-[(E)-4-ammoniobutylidene]propane-1,3-diaminium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58732 CHEBI:10790 methylenediurea biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_10790 CHEBI:58731 gamma-L-glutamylputrescinium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58731 GO:0008929 methylglyoxal synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008929 RHEA:17937|KEGG_REACTION:R01016|MetaCyc:METHGLYSYN-RXN|EC:4.2.3.3 glycerone-phosphate phospho-lyase (methylglyoxal-forming)|glycerone-phosphate phospho-lyase activity|methylglyoxal synthetase activity Catalysis of the reaction: glycerone phosphate = methylglyoxal + phosphate. CHEBI:58730 5-carboxylatoamino-1-(5-O-phosphonato-D-ribosyl)imidazole(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58730 GO:0008928 mannose-1-phosphate guanylyltransferase (GDP) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008928 KEGG_REACTION:R00883|MetaCyc:MANNPGUANYLTRANGDP-RXN|EC:2.7.7.22|RHEA:12905 guanosine diphosphate-mannose 1-phosphate guanylyltransferase activity|GDP:mannose-1-phosphate guanylyltransferase activity|GDP mannose phosphorylase activity|GDP:alpha-D-mannose-1-phosphate guanylyltransferase activity|mannose 1-phosphate (guanosine diphosphate) guanylyltransferase activity|mannose 1-phosphate guanylyltransferase activity|GDP-mannose pyrophosphorylase activity|GDP:D-mannose-1-phosphate guanylyltransferase activity|GDP-mannose phosphorylase activity|GDP-mannose 1-phosphate guanylyltransferase activity|guanosine diphosphomannose phosphorylase activity Catalysis of the reaction: alpha-D-mannose 1-phosphate + GDP + H(+) = GDP-alpha-D-mannose + phosphate. GO:0008938 nicotinate N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008938 KEGG_REACTION:R01721|MetaCyc:NICOTINATE-N-METHYLTRANSFERASE-RXN|RHEA:20241|EC:2.1.1.7 S-adenosyl-L-methionine:nicotinate N-methyltransferase activity|furanocoumarin 8-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine(1+) + nicotinate = N-methylnicotinate + S-adenosyl-L-homocysteine. GO:0008937 ferredoxin-NAD(P) reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008937 EC:1.18.1.- ferredoxin reductase activity Catalysis of the reaction: reduced ferredoxin + NAD(P)+ = oxidized ferredoxin + NAD(P)H + H+. GO:0008936 nicotinamidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008936 EC:3.5.1.19|RHEA:14545|MetaCyc:NICOTINAMID-RXN nicotinamide deaminase activity|nicotinamide amidase activity|NAMase activity|nicotine deamidase activity|nicotinamide amidohydrolase activity|YNDase activity Catalysis of the reaction: nicotinamide + H2O = nicotinate + NH3. GO:0008935 1,4-dihydroxy-2-naphthoyl-CoA synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008935 EC:4.1.3.36|RHEA:15525|MetaCyc:NAPHTHOATE-SYN-RXN|KEGG_REACTION:R04150 DHNA synthetase activity|O-succinylbenzoyl-CoA 1,4-dihydroxy-2-naphthoate-lyase activity|O-succinylbenzoyl-CoA 1,4-dihydroxy-2-naphthoate-lyase (cyclizing; CoA-forming)|1,4-dihydroxy-2-naphthoate synthase activity|O-succinylbenzoyl-CoA 1,4-dihydroxy-2-naphthoate-lyase (cyclizing) activity|dihydroxynaphthoic acid synthetase activity|dihydroxynaphthoate synthase activity Catalysis of the reaction: 4-(2-carboxyphenyl)-4-oxobutanoyl-CoA = 1,4-dihydroxy-2-napthoyl-CoA + H2O. GO:0008934 inositol monophosphate 1-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008934 MetaCyc:RXN0-5408|EC:3.1.3.25|Reactome:R-HSA-1855154|RHEA:27670 myo-inositol-1(or 4)-monophosphatase activity|myo-inositol 1-phosphatase activity|L-myo-inositol-1-phosphate phosphatase activity|myo-inositol-1-phosphatase activity|inositol 1-phosphatase activity|inositol-1(or 4)-monophosphatase activity|myo-inositol-1(or 4)-phosphate phosphohydrolase activity Catalysis of the reaction: myo-inositol 1-phosphate + H2O = myo-inositol + phosphate. CHEBI:58729 N,N-dihydroxy-L-tryptophanate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58729 GO:0008933 lytic transglycosylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008933 EC:3.2.1.- murein transglycosylase B activity|peptidoglycan lytic transglycosylase activity Catalysis of the specific cleavage of the beta-(1->4) glycosidic linkage between N-acetylmuramyl and N-acetylglucosaminyl residues in peptidoglycan, with the concomitant formation of 1,6-anhydro-N-acetylmuramyl residues. CHEBI:58728 N-hydroxy-L-tryptophanate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58728 GO:0008932 lytic endotransglycosylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008932 EC:2.4.99.- murein lytic endotransglycosylase E activity Catalysis of the specific cleavage of the beta-(1->4) glycosidic linkage between N-acetylmuramyl and N-acetylglucosaminyl residues in peptidoglycan, with the concomitant formation of 1,6-anhydro-N-acetylmuramyl residues. Acts on linkages within peptidoglycan chains (i.e. not at the ends) to produce shorter strands with 1,6-anhydromuramic acid ends. CHEBI:58727 N,N-dihydroxy-L-phenylalaninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58727 GO:0008931 obsolete murein DD-endopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008931 murein DD-endopeptidase activity OBSOLETE. (Was not defined before being made obsolete). CHEBI:58726 N-hydroxy-L-phenylalaninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58726 GO:0008930 methylthioadenosine nucleosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008930 EC:3.2.2.16|RHEA:13617|MetaCyc:METHYLTHIOADENOSINE-NUCLEOSIDASE-RXN MeSAdo nucleosidase activity|methylthioadenosine methylthioribohydrolase activity|S-methyl-5'-thioadenosine adeninehyrolase activity|5'-methylthioadenosine nucleosidase activity|MTA nucleosidase activity Catalysis of the reaction: methylthioadenosine + H2O = adenine + 5-methylthio-D-ribose. CHEBI:34779 glyoxal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_34779 CHEBI:10782 (S)-(-)-perillyl alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_10782 CHEBI:58725 2-ammonio-2-deoxy-D-glucopyranose 6-phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58725 CHEBI:58724 threo-3-methyl-L-aspartate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58724 CHEBI:58723 2-ammonio-2-deoxy-D-glucopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58723 CHEBI:58722 N-acetylmuramate 6-phosphate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58722 CHEBI:58721 N-acetyl-beta-muramate 6-phosphate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58721 CHEBI:58720 D-glucopyranuronate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58720 GO:0008939 nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008939 EC:2.4.2.21|KEGG_REACTION:R04148|MetaCyc:DMBPPRIBOSYLTRANS-RXN|RHEA:11196 nicotinate-nucleotide:5,6-dimethylbenzimidazole phospho-D-ribosyltransferase activity|nicotinate mononucleotide (NaMN):5,6-dimethylbenzimidazole phosphoribosyltransferase activity|CobT|N(1)-alpha-phosphoribosyltransferase activity|nicotinate ribonucleotide:benzimidazole (adenine) phosphoribosyltransferase activity|nicotinate-nucleotide:dimethylbenzimidazole phospho-D-ribosyltransferase activity|nicotinate mononucleotide-dimethylbenzimidazole phosphoribosyltransferase activity|N1-alpha-phosphoribosyltransferase activity Catalysis of the reaction: 5,6-dimethylbenzimidazole + nicotinate D-ribonucleotide = alpha-ribazole 5'-phosphate + H(+) + nicotinate. GO:0008905 mannose-phosphate guanylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008905 Catalysis of the transfer of a phosphate group from GTP or GDP to a mannose molecule. GO:0008904 hygromycin-B 7''-O-phosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008904 EC:2.7.1.119|RHEA:23388|KEGG_REACTION:R03770|MetaCyc:HYGROMYCIN-B-KINASE-RXN APH(7'') activity|hygromycin B kinase activity|ATP:hygromycin-B 7''-O-phosphotransferase activity|hygromycin B phosphotransferase activity|hygromycin-B kinase activity|destomic acid ring 7''-O-phosphotransferase activity Catalysis of the reaction: ATP + hygromycin B = 7''-O-phosphohygromycin B + ADP + 2 H(+). GO:0008903 hydroxypyruvate isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008903 RHEA:11952|EC:5.3.1.22|KEGG_REACTION:R01394|MetaCyc:RXN0-305 hydroxypyruvate ketol-isomerase activity|hydroxypyruvate aldose-ketose-isomerase activity Catalysis of the reaction: 3-hydroxypyruvate = 2-hydroxy-3-oxopropanoate. GO:0008902 hydroxymethylpyrimidine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008902 MetaCyc:OHMETPYRKIN-RXN|EC:2.7.1.49|KEGG_REACTION:R03471|RHEA:23096 ATP:4-amino-5-hydroxymethyl-2-methylpyrimidine 5-phosphotransferase activity|hydroxymethylpyrimidine kinase (phosphorylating) Catalysis of the reaction: 4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP = 4-amino-2-methyl-5-phosphomethylpyrimidine + ADP + 2 H(+). CHEBI:58719 primary fluorescent chlorophyll catabolite(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58719 GO:0008901 ferredoxin hydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008901 EC:1.12.7.2|RHEA:17445|MetaCyc:HYDROG-RXN|UM-BBD_enzymeID:e0418 Ni-Fe-Se hydrogenase activity|hydrogenase (ferredoxin) activity|iron-only hydrogenase activity|hydrogenase activity|Ni-Fe hydrogenase activity|H2 producing hydrogenase|hydrogenase II|hydrogenlyase activity|H(2) producing hydrogenase activity|nickel-iron-selenium hydrogenase activity|hydrogen:ferredoxin oxidoreductase activity|H2 oxidizing hydrogenase|uptake hydrogenase activity|iron hydrogenase activity|[Fe] hydrogenase gamma|[Fe] hydrogenase activity|bidirectional hydrogenase activity|hydrogenase I|nickel hydrogenase activity|H(2) oxidizing hydrogenase activity|nickel-iron hydrogenase activity|hydrogen-lyase activity Catalysis of the reaction: 2 reduced ferredoxin + 2 H+ = 2 oxidized ferredoxin + H2. CHEBI:58718 S-substituted N-acetyl-L-cysteinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58718 GO:0008900 potassium:proton exchanging ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008900 Reactome:R-HSA-937311|RHEA:22044|EC:7.2.2.19 H+/K+-ATPase activity|H(+)/K(+)-ATPase activity|H+-K+-ATPase activity|H,K-ATPase activity|proton pump activity|hydrogen:potassium-exchanging ATPase activity|gastric H(+)/K(+) ATPase activity|hydrogen/potassium-exchanging ATPase activity|(K+ + H+)-ATPase activity|hydrogen:potassium exchanging ATPase activity|gastric H+/K+ ATPase|ATP phosphohydrolase (H+/K+-exchanging)|H(+)/K(+)-exchanging ATPase activity|H+/K+-exchanging ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) + K+(out) = ADP + phosphate + H+(out) + K+(in). CHEBI:58717 S-substituted L-cysteine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58717 CHEBI:58716 red chlorophyll catabolite(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58716 CHEBI:58715 calcitroate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58715 CHEBI:58714 beta-L-Ara4N-lipid A(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58714 CHEBI:58713 7-chloro-L-tryptophan zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58713 CHEBI:58712 lipid A(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58712 CHEBI:58711 4-azaniumyl-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58711 GO:0008909 isochorismate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008909 KEGG_REACTION:R01717|EC:5.4.4.2|MetaCyc:ISOCHORSYN-RXN|RHEA:18985 isochorismate synthetase activity|isochorismate mutase activity|isochorismate hydroxymutase activity Catalysis of the reaction: chorismate = isochorismate. CHEBI:58710 UDP-beta-L-threo-pentopyranos-4-ulose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58710 GO:0008908 isochorismatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008908 KEGG_REACTION:R03037|RHEA:11112|EC:3.3.2.1|MetaCyc:ISOCHORMAT-RXN 2,3-dihydroxy-2,3-dihydrobenzoate synthase activity|2,3-dihydro-2,3-dihydroxybenzoate synthase activity|2,3 dihydro-2,3 dihydroxybenzoate synthase activity|isochorismate pyruvate-hydrolase activity|2,3-dihydroxy-2,3-dihydrobenzoic synthase activity Catalysis of the reaction: H(2)O + isochorismate = 2,3-dihydroxy-2,3-dihydrobenzoate + pyruvate. GO:0008907 integrase activity biolink:MolecularActivity go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0008907 Reactome:R-HSA-164523 Catalysis of the integration of one segment of DNA into another. GO:0008906 inosine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008906 EC:2.7.1.73|MetaCyc:INOSINEKIN-RXN|RHEA:21140 ATP:inosine 5'-phosphotransferase activity|inosine kinase (phosphorylating)|inosine-guanosine kinase activity Catalysis of the reaction: ATP + inosine = ADP + IMP. GO:0008916 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008916 GO:0008915 lipid-A-disaccharide synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008915 EC:2.4.1.182|KEGG_REACTION:R04606|RHEA:22668|MetaCyc:LIPIDADISACCHARIDESYNTH-RXN UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine:2,3-bis-(3-hydroxytetradecanoyl)-beta-D-glucosaminyl-1-phosphate 2,3-bis(3-hydroxytetradecanoyl)-glucosaminyltransferase activity Catalysis of the reaction: 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + UDP-2,3-bis(3-hydroxytetradecanoyl)-D-glucosamine = 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-(1->6)-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + H(+) + UDP. GO:0008914 leucyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008914 MetaCyc:LEUCYLTRANSFERASE-RXN|EC:2.3.2.6|RHEA:12340 leucyl-phenylalanine-transfer ribonucleate-protein aminoacyltransferase activity|leucyl, phenylalanine-tRNA-protein transferase activity|L-leucyl-tRNA:protein leucyltransferase activity|leucyl/phenylalanyl-tRNA--protein transferase activity|leucyl-tRNA--protein transferase activity|leucyl-phenylalanine-transfer ribonucleate-protein transferase activity|L/F transferase activity Catalysis of the reaction: L-leucyl-tRNA + protein = tRNA + L-leucyl-protein. CHEBI:58709 UDP-4-deoxy-4-formamido-beta-L-arabinopyranose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58709 GO:0008913 lauroyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008913 lauroyl transferase activity Catalysis of the transfer of a lauroyl (dodecanoyl) group from one compound to another. CHEBI:58708 UDP-4-amino-4-deoxy-beta-L-arabinopyranose(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58708 GO:0008912 lactaldehyde reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008912 EC:1.1.1.77 (R)- or (S)-propane-1,2-diol:NAD+ oxidoreductase activity|lactaldehyde:propanediol oxidoreductase activity|propanediol:nicotinamide adenine dinucleotide (NAD) oxidoreductase activity|propanediol oxidoreductase activity Catalysis of the reaction: propane-1,2-diol + NAD+ = lactaldehyde + NADH + H+. CHEBI:58706 L-methioninium (R)-S-oxide residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58706 GO:0008911 lactaldehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008911 MetaCyc:LACTALDDEHYDROG-RXN|EC:1.2.1.22|RHEA:14277 (S)-lactaldehyde:NAD+ oxidoreductase activity|L-lactaldehyde:NAD oxidoreductase activity|nicotinamide adenine dinucleotide (NAD)-linked dehydrogenase activity Catalysis of the reaction: (S)-lactaldehyde + NAD+ + H2O = (S)-lactate + NADH + H+. UBERON:0005519 rhombomere 6 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005519 r6 the sixth transiently divided segment of the developing rhombencephalon; rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates; rhombomeres are numbered in caudal to rostral order GO:0008910 kanamycin kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008910 KEGG_REACTION:R01888|MetaCyc:KANAMYCIN-KINASE-RXN|RHEA:24256|EC:2.7.1.95 kanamycin kinase (phosphorylating)|ATP:kanamycin 3'-O-phosphotransferase activity|neomycin-kanamycin phosphotransferase activity|aminoglycoside 3'-phosphotransferase activity|neomycin phosphotransferase activity|APH(3') activity Catalysis of the reaction: ATP + kanamycin = ADP + 2 H(+) + kanamycin 3'-phosphate. CHEBI:58705 N-acetyl-beta-neuraminate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58705 CHEBI:58704 3,3,3-tetraminium(4+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58704 CHEBI:20114 3-methylquinolin-2(1H)-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_20114 UBERON:0005527 rhombomere 8 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005527 r8 the eighth transiently divided segment of the developing rhombencephalon; rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates; rhombomeres are numbered in caudal to rostral order CHEBI:58703 7-ammoniomethyl-7-deazaguanine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58703 CHEBI:58702 phosphonatoenolpyruvate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58702 CHEBI:19138 12-HETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19138 CHEBI:58700 6-(alpha-D-glucosazaniumyl)-1D-myo-inositol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58700 UBERON:0005523 rhombomere 7 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005523 r7 the seventh transiently divided segment of the developing rhombencephalon; rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates; rhombomeres are numbered in caudal to rostral order GO:0008919 lipopolysaccharide glucosyltransferase I activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008919 MetaCyc:2.4.1.58-RXN|EC:2.4.1.58 lipopolysaccharide glucosyltransferase activity|LPS glucosyltransferase I activity|UDPglucose:lipopolysaccharide glucosyltransferase activity|UDPglucose:lipopolysaccharide glucosyltransferase I|uridine diphosphate glucose:lipopolysaccharide glucosyltransferase I|UDP-glucose:lipopolysaccharide glucosyltransferase activity|uridine diphosphoglucose-lipopolysaccharide glucosyltransferase activity Catalysis of the reaction: UDP-glucose + lipopolysaccharide = UDP + D-glucosyl-lipopolysaccharide. GO:0008918 lipopolysaccharide 3-alpha-galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008918 MetaCyc:2.4.1.44-RXN|EC:2.4.1.44 lipopolysaccharide-alpha-1,3-D-galactosyltransferase|UDP-galactose:lipopolysaccharide 3-alpha-D-galactosyltransferase activity|LPS 3-alpha-galactosyltransferase activity|UDP-galactose:lipopolysaccharide alpha,3-galactosyltransferase activity|lipopolysaccharide galactosyltransferase activity|uridine diphosphogalactose-lipopolysaccharide alpha,3-galactosyltransferase activity|UDPgalactose:lipopolysaccharide 3-alpha-D-galactosyltransferase activity|UDP-galactose:polysaccharide galactosyltransferase activity|lipopolysaccharide 1,3-galactosyltransferase activity|uridine diphosphate galactose:lipopolysaccharide alpha-3-galactosyltransferase activity Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,3 alpha-D-galactosyl-lipopolysaccharide. GO:0008917 lipopolysaccharide N-acetylglucosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008917 MetaCyc:2.4.1.56-RXN|EC:2.4.1.56 UDP-N-acetyl-D-glucosamine:lipopolysaccharide N-acetyl-D-glucosaminyltransferase activity|UDP-N-acetylglucosamine-lipopolysaccharide N-acetylglucosaminyltransferase activity|LPS N-acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-lipopolysaccharide acetylglucosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + lipopolysaccharide = UDP + N-acetyl-D-glucosaminyl-lipopolysaccharide. GO:0018490 4-hydroxyphenylpyruvate oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018490 KEGG_REACTION:R00042|MetaCyc:1.2.3.13-RXN|RHEA:17197|EC:1.2.3.13|UM-BBD_reactionID:r0299 4-hydroxyphenylpyruvate:oxygen oxidoreductase (decarboxylating) Catalysis of the reaction: 2 (4-hydroxyphenyl)pyruvate + O(2) = 2 (4-hydroxyphenyl)acetate + 2 CO(2). GO:0018492 carbon-monoxide dehydrogenase (acceptor) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018492 EC:1.2.7.4|RHEA:21040|MetaCyc:CARBON-MONOXIDE-DEHYDROGENASE-RXN|UM-BBD_enzymeID:e0415 anaerobic carbon monoxide dehydrogenase activity|carbon monoxide dehydrogenase activity|carbon-monoxide:acceptor oxidoreductase activity Catalysis of the reaction: CO + H2O + acceptor = CO2 + reduced acceptor. GO:0018491 2-oxobutyrate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018491 UM-BBD_reactionID:r0358|MetaCyc:2-OXOBUTYRATE-SYNTHASE-RXN|RHEA:32135 2-oxobutanoate:ferredoxin 2-oxidoreductase (CoA-propionylating)|2-ketobutyrate synthase activity|alpha-ketobutyrate-ferredoxin oxidoreductase activity|alpha-ketobutyrate synthase activity|2-oxobutyrate-ferredoxin oxidoreductase activity Catalysis of the reaction: 2-oxobutanoate + CoA + oxidized ferredoxin = propanoyl-CoA + CO2 + reduced ferredoxin. GO:0043454 alkyne catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043454 alkyne degradation|alkyne breakdown|alkyne catabolism The chemical reactions and pathways resulting in the breakdown of an alkyne, any acyclic branched or unbranched hydrocarbon (compound composed only of carbon and hydrogen) having a carbon-carbon triple bond and the general formula CnH2n-2. GO:0043453 alkyne biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043453 alkyne anabolism|alkyne synthesis|alkyne formation|alkyne biosynthesis The chemical reactions and pathways resulting in the formation of an alkyne, any acyclic branched or unbranched hydrocarbon (compound composed only of carbon and hydrogen) having a carbon-carbon triple bond and the general formula CnH2n-2. GO:0043456 regulation of pentose-phosphate shunt biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043456 regulation of pentose phosphate shunt|regulation of pentose-phosphate pathway|regulation of pentose phosphate pathway Any process that modulates the frequency, rate or extent of the pentose-phosphate shunt, the process in which glucose is oxidized, coupled to NADPH synthesis. GO:0043455 regulation of secondary metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043455 regulation of secondary metabolism Any process that modulates the frequency, rate or extent of secondary metabolism, the chemical reactions and pathways involving compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. GO:0043450 alkene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043450 alkene anabolism|alkene synthesis|alkene biosynthesis|alkene formation The chemical reactions and pathways resulting in the formation of an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n. GO:0043452 cellular alkyne metabolic process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0043452 alkyne metabolism The chemical reactions and pathways involving an alkyne, any acyclic branched or unbranched hydrocarbon (compound composed only of carbon and hydrogen) having a carbon-carbon triple bond and the general formula CnH2n-2, as carried out by individual cells. CHEBI:83697 N(5)-alkyl-L-glutamine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83697 GO:0043451 alkene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043451 alkene catabolism|alkene degradation|alkene breakdown The chemical reactions and pathways resulting in the breakdown of an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n. CHEBI:138347 triacylglycerol 54:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138347 GO:0043458 ethanol biosynthetic process involved in glucose fermentation to ethanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043458 ethanol anabolism during fermentation|ethanol synthesis during fermentation|ethanol formation during fermentation The chemical reactions and pathways resulting in the formation of ethanol, CH3-CH2-OH, as part of the process of glucose catabolism to ethanol, CO2 and ATP. CHEBI:83690 N-terminal N-acetyl-L-serine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83690 GO:0043457 regulation of cellular respiration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043457 Any process that modulates the frequency, rate or extent of cellular respiration, the enzymatic release of energy from organic compounds. CL:0005019 pancreatic epsilon cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0005019 pancreatic E cell Ghrelin secreting cells found in the exocrine pancreas. CL:0005018 ghrelin secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0005018 A cell that secretes ghrelin, the peptide hormone that stimulates hunger. GO:0043459 obsolete response to short exposure to lithium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043459 response to short exposure to lithium ion OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a single or short exposure to a lithium ion stimulus. GO:0018487 vanillate O-demethylase (anaerobic) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018487 UM-BBD_reactionID:r0758 Catalysis of the reaction: vanillate + Co+ = Co3+-CH3 + 3,4-dihydroxybenzoate. GO:0018486 2-butanone oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018486 UM-BBD_reactionID:r0169 Catalysis of the reaction: methyl ethyl ketone + O2 = H2O + ethyl acetate. CHEBI:138341 (R)-2-alkyl-3-oxoalkanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138341 GO:0018489 vanillate monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018489 MetaCyc:RXN-2|MetaCyc:RXN-10891|EC:1.14.13.82|UM-BBD_reactionID:r0146|RHEA:13021|KEGG_REACTION:R05274 vanillate:oxygen oxidoreductase (demethylating)|vanillate demethylase (aerobic) activity|vanillate demethylase activity|4-hydroxy-3-methoxybenzoate demethylase activity Catalysis of the reaction: H(+) + NADH + O(2) + vanillate = 3,4-dihydroxybenzoate + formaldehyde + H(2)O + NAD(+). CHEBI:138340 (2R,3S)-2-alkyl-3-hydroxyalkanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138340 GO:0018488 aryl-aldehyde oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018488 MetaCyc:ARYL-ALDEHYDE-OXIDASE-RXN|UM-BBD_reactionID:r0145|EC:1.2.3.9|RHEA:18569 aryl-aldehyde:oxygen oxidoreductase activity Catalysis of the reaction: an aromatic aldehyde + O2 + H2O = an aromatic acid + hydrogen peroxide. GO:0018483 6-oxohexanoate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018483 EC:1.2.1.63|MetaCyc:6-OXOHEXANOATE-OXIDATION-RXN|UM-BBD_reactionID:r0175|RHEA:13397 6-oxohexanoate:NADP+ oxidoreductase activity Catalysis of the reaction: 6-oxohexanoate + NADP+ + H2O = adipate + NADPH + H+. CHEBI:138346 triacylglycerol 54:9 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138346 CL:0005012 multi-ciliated epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0005012 multiciliated epithelial cell|multiciliated cell|MCC|multi-ciliated cell A ciliated epithelial cell with many cilium. GO:0018482 4-formylbenzenesulfonate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018482 EC:1.2.1.62|RHEA:18833|UM-BBD_reactionID:r0292|KEGG_REACTION:R05272|MetaCyc:1.2.1.62-RXN 4-formylbenzenesulfonate:NAD+ oxidoreductase activity|4-formylbenzenesulphonate dehydrogenase activity|toluene-sulfonate aldehyde dehydrogenase activity Catalysis of the reaction: 4-formylbenzenesulfonate + H(2)O + NAD(+) = 4-sulfobenzoate + 2 H(+) + NADH. GO:0018485 salicylaldehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018485 UM-BBD_enzymeID:e0256|EC:1.2.1.65|RHEA:18537|MetaCyc:1.2.1.65-RXN salicylaldehyde:NAD+ oxidoreductase activity Catalysis of the reaction: salicylaldehyde + NAD+ + H2O = salicylate + NADH + H+. GO:0018484 4-hydroxybenzaldehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018484 RHEA:20305|EC:1.2.1.64|MetaCyc:HYDROXYBENZALDEHYDE-OXIDATION-NAD-RXN|UM-BBD_reactionID:r0273 p-hydroxybenzaldehyde dehydrogenase activity|3-hydroxybenzaldehyde:NAD+ oxidoreductase activity Catalysis of the reaction: 4-hydroxybenzaldehyde + NAD+ + H2O = 4-hydroxybenzoate + NADH + H+. GO:0043465 regulation of fermentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043465 Any process that modulates the frequency, rate or extent of fermentation, the anaerobic enzymatic conversion of organic compounds, especially carbohydrates, to other compounds, especially to ethyl alcohol, resulting in energy in the form of adenosine triphosphate (ATP). GO:0043464 malolactic fermentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043464 Wikipedia:Malolactic_fermentation malate fermentation|L-malate fermentation|malolactate fermentation|malo-lactate fermentation The anaerobic enzymatic conversion of L-malate to L-lactate and carbon dioxide, yielding energy in the form of ATP. GO:0043467 regulation of generation of precursor metabolites and energy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043467 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and the processes involved in the liberation of energy from these substances. GO:0043466 pyrimidine nucleobase fermentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043466 pyrimidine base fermentation|pyrimidine fermentation The anaerobic conversion of pyrimidine nucleobases, yielding energy in the form of ATP. GO:0043461 proton-transporting ATP synthase complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043461 F-type ATPase complex assembly The aggregation, arrangement and bonding together of a proton-transporting ATP synthase (also known as F-type ATPase), a two-sector ATPase found in the inner membrane of mitochondria and chloroplasts, and in bacterial plasma membranes. GO:0043460 obsolete response to long exposure to lithium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043460 response to long exposure to lithium ion OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a long or persistent exposure to a lithium ion stimulus. GO:0043463 regulation of rhamnose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043463 regulation of rhamnose degradation|regulation of rhamnose breakdown|regulation of rhamnose catabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose. CHEBI:44089 (2S)-2-methyltetradecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_44089 GO:0043462 regulation of ATPase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043462 regulation of adenosinetriphosphatase activity Any process that modulates the rate of ATP hydrolysis by an ATPase. CHEBI:138359 4,4'-disulfanyldibutanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138359 CL:0005026 hepatoblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0005026 Multi fate stem cell that gives rise to both hepatocytes and cholangiocytes as descendants. CHEBI:138358 4-sulfanylbutanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138358 GO:0043469 regulation of D-xylose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043469 Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of xylose. GO:0043468 regulation of fucose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043468 Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of fucose. GO:0018498 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018498 UM-BBD_enzymeID:e0308|RHEA:25062|MetaCyc:PHENPRODIOLDEHYDROG-RXN Catalysis of the reaction: cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol + NAD+ = NADH + H+ + 3-(2,3-dihydroxyphenyl)propionate. CL:0005020 lymphangioblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0005020 Lymphatic progenitor cells. GO:0018497 1-chloro-2,2-bis(4-chlorophenyl)ethane dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018497 UM-BBD_reactionID:r0514 DDMS dehydrogenase activity Catalysis of the reaction: 1-chloro-2,2-bis(4-chlorophenyl)ethene + 2 H+ + 2 e- = 1-chloro-2,2-bis(4-chlorophenyl)ethane. 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU; 1-chloro-2,2-bis(4-chlorophenyl)ethane is also known as DDMS. GO:0018499 cis-2,3-dihydrodiol DDT dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018499 UM-BBD_reactionID:r0451 Catalysis of the reaction: cis-2,3-dihydrodiol DDT + NADP+ = NADPH + 2,3-dihydroxy DDT. CL:0005024 somatomotor neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0005024 somatic motor neuron A motor neuron that innervates a skeletal muscle. These motor neurons are all excitatory and cholinergic. GO:0018494 carvone reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018494 EC:1.3.99.25|MetaCyc:RXN-9419|MetaCyc:RXN-9403|UM-BBD_reactionID:r0732 Catalysis of the reaction: carvone + 2 H+ + 2 e- = dihydrocarvone. GO:0018493 formylmethanofuran dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018493 KEGG_REACTION:R03015|RHEA:19841|MetaCyc:FORMYLMETHANOFURAN-DEHYDROGENASE-RXN|UM-BBD_reactionID:r0345|EC:1.2.7.12 formylmethanofuran:(acceptor) oxidoreductase activity|formylmethanofuran:acceptor oxidoreductase activity Catalysis of the reaction: N-formylmethanofuran + A + H(2)O + H(+) = AH(2) + CO(2) + methanofuran. CL:0005022 vascular lymphangioblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0005022 parachordal lymphangioblast Lymphatic progenitor cells, derived from the veins, that give rise to lymphatic endothelial cells. GO:0018496 2,6-dihydroxycyclohexane-1-carboxyl-CoA dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018496 UM-BBD_reactionID:r0205 Catalysis of the reaction: 2,6-dihydroxycyclohexane-1-carboxyl-CoA = 2 H+ + 2 e- + 6-oxo-2-hydroxycyclohexane-1-carboxyl-CoA. GO:0018495 2-hydroxycyclohexane-1-carboxyl-CoA dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018495 UM-BBD_reactionID:r0192 Catalysis of the reaction: 2-hydroxycyclohexane-1-carboxyl-CoA = 2 H+ + 2 e- + 2-ketocyclohexane-1-carboxyl-CoA. CHEBI:44075 methyl L-leucinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_44075 GO:0043470 regulation of carbohydrate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043470 Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates. GO:0018470 4-hydroxybutaraldehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018470 UM-BBD_reactionID:r0014 Catalysis of the reaction: 4-hydroxybutyraldehyde + H2O = 2 H+ + 2 e- + 4-hydroxybutanoate. CHEBI:44074 molybdopterin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_44074 GO:0043476 pigment accumulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043476 pigment accumulation in response to external stimulus The aggregation of coloring matter in a particular location in an organism, tissue or cell, occurring in response to some external stimulus. GO:0043475 pigment metabolic process involved in pigment accumulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043475 pigment metabolism during pigment accumulation|pigment metabolic process during pigment accumulation The chemical reactions and pathways involving a pigment, any general or particular coloring matter in living organisms, as part of the accumulation of pigment. GO:0043478 pigment accumulation in response to UV light biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043478 The aggregation of coloring matter in a particular location in an organism, tissue or cell, occurring in response to a UV light stimulus. GO:0043477 pigment biosynthetic process involved in pigment accumulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043477 pigment biosynthetic process during pigment accumulation The chemical reactions and pathways resulting in the formation of a pigment, any general or particular coloring matter in living organisms, resulting in pigment accumulation. GO:0043472 IgD binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043472 Interacting selectively and non-covalently with an immunoglobulin of a D isotype. GO:0043471 regulation of cellular carbohydrate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043471 Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates, carried out by individual cells. GO:0043474 pigment metabolic process involved in pigmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043474 pigment metabolism during pigmentation|pigment metabolic process during pigmentation The chemical reactions and pathways involving a pigment, any general or particular coloring matter in living organisms, resulting in the deposition or aggregation of pigment in an organism, tissue or cell. GO:0043473 pigmentation biolink:BiologicalProcess go-plus goslim_chembl|goslim_pir|goslim_generic http://purl.obolibrary.org/obo/GO_0043473 The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells. CHEBI:138328 L-firefly luciferyl-CoA(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138328 CHEBI:138327 hydroperoxy(hydroxy)icosatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138327 CHEBI:138326 (5S,6R)-dihydroxy-(15S)-hydroperoxy-(7E,9E,11Z,13E)-icosatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138326 CHEBI:138325 (5S)-hydroxy-(15S)-hydroperoxy-(6E,8Z,11Z,13E)-icosatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138325 GO:0018469 myrtenal dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018469 UM-BBD_reactionID:r0711 Catalysis of the reaction: myrtenal + H2O = 2 H+ + 2 e- + myrtenic acid. GO:0018468 alcohol dehydrogenase (acceptor) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018468 EC:1.1.99.8|UM-BBD_enzymeID:e0004 alcohol:acceptor oxidoreductase activity|quinoprotein alcohol dehydrogenase activity|MDH|quinohemoprotein alcohol dehydrogenase activity|PQQ-dependent alcohol dehydrogenase activity|alcohol:(acceptor) oxidoreductase activity|quinoprotein ethanol dehydrogenase activity|primary alcohol dehydrogenase Catalysis of the reaction: a primary alcohol + acceptor = an aldehyde + reduced acceptor. GO:0043479 pigment accumulation in tissues in response to UV light biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043479 The aggregation of coloring matter in a particular location in a tissue, occurring in response to a UV light stimulus. CHEBI:138329 ent-Photinus luciferin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138329 GO:0018465 vanillyl-alcohol oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018465 EC:1.1.3.38|KEGG_REACTION:R02877|UM-BBD_reactionID:r0651|RHEA:10036|MetaCyc:1.1.3.38-RXN 4-hydroxy-2-methoxybenzyl alcohol oxidase activity|vanillyl alcohol:oxygen oxidoreductase activity Catalysis of the reaction: O(2) + vanillyl alcohol = H(2)O(2) + vanillin. CHEBI:138320 monoalkyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138320 GO:0018464 3-hydroxypimeloyl-CoA dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018464 KEGG_REACTION:R05305|RHEA:11168|UM-BBD_reactionID:r0196|MetaCyc:1.1.1.259-RXN|EC:1.1.1.259 3-hydroxypimeloyl-CoA:NAD+ oxidoreductase activity Catalysis of the reaction: 3-hydroxypimelyl-CoA + NAD(+) = 3-oxopimelyl-CoA + H(+) + NADH. GO:0018467 formaldehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018467 MetaCyc:FORMALDEHYDE-DEHYDROGENASE-RXN|EC:1.2.1.46|KEGG_REACTION:R00604|UM-BBD_reactionID:r0240|RHEA:16425 glutathione-independent formaldehyde dehydrogenase activity|formaldehyde:NAD+ oxidoreductase activity Catalysis of the reaction: formaldehyde + H(2)O + NAD(+) = formate + 2 H(+) + NADH. GO:0018466 limonene-1,2-diol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018466 EC:1.1.99.-|UM-BBD_reactionID:r0735 Catalysis of the reaction: (1S,2S,4R)-limonene-1,2-diol + DCPIP+ = DCPIPH + H+ + (1S,4R)-1-hydroxy-2-oxolimonene. GO:0018461 fluoren-9-ol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018461 EC:1.1.1.256|UM-BBD_reactionID:r0408|MetaCyc:9-FLUORENOL-DEHYDROGENASE-RXN 9-fluorenol dehydrogenase activity|fluoren-9-ol:NAD(P)+ oxidoreductase activity Catalysis of the reaction: fluoren-9-ol + 2 NADP+ = fluoren-9-one + 2 NADPH + 2 H+. GO:0018460 cyclohexanol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018460 UM-BBD_reactionID:r0165|RHEA:10044|MetaCyc:CYCLOHEXANOL-DEHYDROGENASE-RXN|EC:1.1.1.245 cyclohexanol:NAD+ oxidoreductase activity Catalysis of the reaction: cyclohexanol + NAD+ = cyclohexanone + NADH + H+. GO:0018463 6-hydroxyhexanoate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018463 UM-BBD_reactionID:r0174|RHEA:14225|MetaCyc:6-HYDROXYHEXANOATE-OXIDATION-RXN|EC:1.1.1.258|KEGG_REACTION:R05283 6-hydroxyhexanoate:NAD+ oxidoreductase activity Catalysis of the reaction: 6-hydroxyhexanoate + NAD(+) = 6-oxohexanoate + H(+) + NADH. GO:0018462 4-(hydroxymethyl)benzenesulfonate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018462 RHEA:24412|MetaCyc:1.1.1.257-RXN|UM-BBD_reactionID:r0291|EC:1.1.1.257|KEGG_REACTION:R05271 4-sulfobenzyl alcohol dehydrogenase activity|4-(hydroxymethyl)benzenesulfonate:NAD+ oxidoreductase activity|4-(hydroxymethyl)benzenesulphonate dehydrogenase activity Catalysis of the reaction: 4-(hydroxymethyl)benzenesulfonate + NAD(+) = 4-formylbenzenesulfonate + H(+) + NADH. CHEBI:138321 O-[S-(4-hydroxybenzoyl)pantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138321 GO:0018481 4-hydroxymuconic-semialdehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018481 UM-BBD_reactionID:r0229|EC:1.2.1.61|RHEA:22420|KEGG_REACTION:R05236|MetaCyc:1.2.1.61-RXN 4-hydroxymuconic-semialdehyde:NAD+ oxidoreductase activity Catalysis of the reaction: cis,trans-4-hydroxymuconate semialdehyde + H(2)O + NAD(+) = 2 H(+) + maleylacetate + NADH. GO:0043481 anthocyanin accumulation in tissues in response to UV light biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043481 The aggregation of the pigment anthocyanin in a particular location in a tissue, occurring in response to a UV light stimulus. GO:0043480 pigment accumulation in tissues biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043480 organismal pigment accumulation The aggregation of coloring matter in a particular location in a tissue, occurring in response to an external stimulus. GO:0018480 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018480 UM-BBD_reactionID:r0365|EC:1.2.1.60|RHEA:15681|MetaCyc:CHMS-DEHYDROGENASE-RXN 5-carboxymethyl-2-hydroxymuconic-semialdehyde:NAD+ oxidoreductase activity|carboxymethylhydroxymuconic semialdehyde dehydrogenase activity Catalysis of the reaction: 5-carboxymethyl-2-hydroxymuconate semialdehyde + H2O + NAD+ = 5-carboxymethyl-2-hydroxymuconate + NADH + H+. PR:000020795 neurotrophin-3 proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000020795 NTF3/ClvPrd A neurotrophin-3 that has been processed by proteolytic cleavage. GO:0043487 regulation of RNA stability biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043487 Any process that modulates the propensity of RNA molecules to degradation. Includes processes that both stabilize and destabilize RNAs. GO:0043486 histone exchange biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043486 histone replacement|histone chaperone The replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits. GO:0043489 RNA stabilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043489 Prevention of degradation of RNA molecules. GO:0043488 regulation of mRNA stability biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043488 Any process that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs. GO:0043483 anthocyanin biosynthetic process involved in anthocyanin accumulation in response to UV light biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043483 anthocyanin biosynthetic process during anthocyanin accumulation in response to UV light|anthocyanin biosynthetic process during anthocyanin accumulation in tissues in response to UV light stimulus|anthocyanin biosynthesis during anthocyanin accumulation in tissues in response to UV light stimulus The chemical reactions and pathways resulting in the formation of the pigment anthocyanin, contributing to anthocyanin accumulation in a tissue in response to a UV light stimulus. GO:0043482 cellular pigment accumulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043482 The aggregation of coloring matter in a particular location in a cell, occurring in response to some external stimulus. GO:0043485 endosome to pigment granule transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043485 The directed movement of substances from endosomes to pigment granules. GO:0043484 regulation of RNA splicing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043484 Any process that modulates the frequency, rate or extent of RNA splicing, the process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA. CL:0005006 ionocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0005006 Specialized epithelial cells involved in the maintenance of osmotic homeostasis. They are characterized by abundant mitochondria and ion transporters. In amniotes, they are present in the renal system. In freshwater fish, ionocytes in the skin and gills help maintain osmotic homeostasis by absorbing salt from the external environment. CHEBI:138339 2-[(11R)-hydroxy-(5Z,8Z,12E,14Z)-icosatetraenoyl]-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138339 CL:0005005 cyanoblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0005005 A non-terminally differentiated cell that originates from the neural crest and differentiates into a cyanophore. CL:0005004 pigment erythroblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0005004 A non-terminally differentiated cell that originates from the neural crest and differentiates into an erythrophore. CL:0005003 leucoblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0005003 A non-terminally differentiated cell that originates from the neural crest and differentiates into a leucophore. GO:0018479 benzaldehyde dehydrogenase (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018479 UM-BBD_reactionID:r0269|RHEA:11840|MetaCyc:BENZALDEHYDE-DEHYDROGENASE-NAD+-RXN|EC:1.2.1.28 benzaldehyde (NAD) dehydrogenase activity|benzaldehyde:NAD+ oxidoreductase activity Catalysis of the reaction: benzaldehyde + NAD+ + H2O = benzoate + NADH + H+. CHEBI:138331 cholesteryl icosatrienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138331 GO:0018476 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018476 OBO:GOCHE_60311 substance with thyroid hormone role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_60311 CHEBI:138330 pyridinium-3-carboxylate-5-thiocarboxylate mononucleotide(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138330 GO:0018475 trans-2-methyl-5-isopropylhexa-2,5-dienal dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018475 UM-BBD_reactionID:r0745 Catalysis of the reaction: trans-2-methyl-5-isopropylhexa-2,5-dienal + NAD+ + H2O = NADH + H+ + trans-2-methyl-5-isopropylhexa-2,5-dienoic acid. GO:0018478 malonate-semialdehyde dehydrogenase (acetylating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018478 RHEA:22988|MetaCyc:1.2.1.18-RXN|EC:1.2.1.18 malonic semialdehyde oxidative decarboxylase activity|3-oxopropanoate:NAD(P)+ oxidoreductase (decarboxylating, CoA-acetylating) Catalysis of the reaction: 3-oxopropanoate + CoA + NADP+ = acetyl-CoA + CO2 + NADPH + H+. GO:0018477 benzaldehyde dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018477 RHEA:21660|EC:1.2.1.7|MetaCyc:BENZALDEHYDE-DEHYDROGENASE-NADP+-RXN|UM-BBD_enzymeID:e0079 NADP-linked benzaldehyde dehydrogenase|benzaldehyde:NADP+ oxidoreductase Catalysis of the reaction: benzaldehyde + NADP+ + H2O = benzoate + NADPH + H+. GO:0018472 1-hydroxy-2-naphthaldehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018472 UM-BBD_reactionID:r0485 Catalysis of the reaction: 1-hydroxy-2-naphthaldehyde + NAD+ + H2O = NADH + H+ + 1-hydroxy-2-naphthoate. CL:0005002 xanthoblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0005002 A non-terminally differentiated cell that differentiates into a xanthophore. CL:0005001 iridoblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0005001 A non-terminally differentiated cell that originates from the neural crest and differentiates into an iridophore. CHEBI:138334 N(tele)-(N(7)-methylguanosine 5'-phosphonato)-L-histidine zwitterion residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138334 GO:0018471 4-chlorobenzaldehyde oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018471 EC:1.14.13.-|UM-BBD_reactionID:r0447 Catalysis of the reaction: 4-chlorobenzaldehyde + 2 H2O = 4-chlorobenzoate + 2 H+ + 2 e-. CL:0005000 spinal cord interneuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0005000 A CNS interneuron located in the spinal cord. GO:0018474 2-carboxybenzaldehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018474 UM-BBD_reactionID:r0490|EC:1.2.1.- Catalysis of the reaction: 2-carboxybenzaldehyde + NAD+ + H2O = NADH + 2 H+ + phthalate. CHEBI:138332 11(S)-HETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138332 GO:0018473 cis-2-methyl-5-isopropylhexa-2,5-dienal dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018473 UM-BBD_reactionID:r0744 Catalysis of the reaction: cis-2-methyl-5-isopropylhexa-2,5-dienal + NAD+ + H2O = NADH + H+ + cis-2-methyl-5-isopropylhexa-2,5-dienoic acid. GO:0043490 malate-aspartate shuttle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043490 Wikipedia:Malate-aspartate_shuttle malate:aspartate shuttle|malate aspartate shuttle|malate/aspartate shuttle The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise malate in the cytosol; this compound is then transported into the mitochondria where it is converted to oxaloacetate using NADH, the oxaloacetate reacts with gluamate to form aspartate, and the aspartate then returns to the cytosol to complete the cycle. CHEBI:19098 1-pyrrolinecarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19098 GO:0043492 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043492 GO:0043491 protein kinase B signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043491 PKB signaling cascade|protein kinase B signal transduction|protein kinase B signalling cascade|AKT signalling cascade|PKB signalling cascade|protein kinase B signaling cascade|AKT signaling|PKB signaling|AKT signal transduction|PKB signal transduction|AKT signaling cascade A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase B (also called AKT), which occurs as a result of a single trigger reaction or compound. CHEBI:19092 1-pyrroline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19092 GO:0043498 obsolete cell surface binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043498 cell surface binding OBSOLETE. Interacting selectively and non-covalently with any component on the surface of a cell. GO:0043497 regulation of protein heterodimerization activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043497 Any process that modulates the frequency, rate or extent of protein heterodimerization, interacting selectively with a nonidentical protein to form a heterodimer. CHEBI:20081 3-hydroxypropionyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20081 GO:0043499 obsolete eukaryotic cell surface binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043499 eukaryotic cell surface binding OBSOLETE. Interacting selectively and non-covalently with any component on the surface of a eukaryotic cell. GO:0043494 CLRC complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043494 CLRC ubiquitin ligase complex|Rik1-E3 ubiquitin ligase complex|Rik1 E3 ubiquitin ligase complex|Clr4-Rik1-Cul4 complex An cullin-dependent E3 ubiquitin ligase/histone H3-K9 methyltransferase complex essential for heterochromatin assembly by RNAi. GO:0043493 viral terminase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043493 virus terminase complex|phage terminase complex A complex of a large and small subunit which catalyze the packaging of DNA into viral heads. Note that not all viral terminases have this structure, some exist as single polypeptides. GO:0043496 regulation of protein homodimerization activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043496 Any process that modulates the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer. GO:0043495 protein-membrane adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043495 anchoring|protein membrane anchor|protein membrane adaptor activity|protein membrane adaptor The binding activity of a molecule that brings together a protein or a protein complex with a membrane, or bringing together two membranes, either via membrane lipid binding or by interacting with a membrane protein, to establish or maintain the localization of the protein, protein complex or organelle. CHEBI:138306 aromatic (S)-hydroxynitrile biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138306 CHEBI:58695 D-tagatofuranose 6-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58695 CHEBI:58694 D-tagatofuranose 1,6-bisphosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58694 CHEBI:138305 (21S)-21,22-epoxypolypoda-8(26)-13,17-trien-3beta-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138305 CHEBI:58693 (7R)-7-(4-carboxylatobutanamido)cephalosporanate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58693 CHEBI:138303 alpha-onocerin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138303 CHEBI:58692 (R)-2-benzylsuccinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58692 GO:0018447 chloral hydrate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018447 UM-BBD_enzymeID:e0229 Catalysis of the reactions: chloral hydrate = 3 H+ + 2 e- + trichloroacetate, and chloral hydrate + H2 = H2O + trichloroethanol. CHEBI:58691 (3R,4S,5R)-3,4,5-trihydroxy-6-oxocyclohex-1-en-1-olate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58691 CHEBI:138309 C-terminal L-alpha-amino-acid-L-tyrosinate residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138309 GO:0018446 pinocarveol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018446 UM-BBD_reactionID:r0717 Catalysis of the reaction: pinocarveol = pinocarvone + 2 H+ + 2 e-. CHEBI:58690 1,6-anhydro-N-acetyl-beta-muramate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58690 GO:0018449 1-phenylethanol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018449 UM-BBD_reactionID:r0032 Catalysis of the reaction: (S)-1-phenylethanol = acetophenone + H2. CHEBI:138307 (3S,22S)-2,3:22,23-diepoxy-2,3,22,23-tetrahydrosqualene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138307 GO:0018448 hydroxymethylmethylsilanediol oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018448 UM-BBD_reactionID:r0638 Catalysis of the reaction: hydroxymethylmethylsilanediol + O2 + 2 H+ + 2 e- = formylmethylsilanediol + 2 H2O. GO:0018443 obsolete enzyme active site formation via L-aspartic 4-phosphoric anhydride biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018443 RESID:AA0033 OBSOLETE. The transient phosphorylation of peptidyl-aspartic acid to form L-aspartic 4-phosphoric anhydride. GO:0018442 peptidyl-glutamic acid esterification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018442 The addition of an ester group to a glutamic acid residue in a protein. GO:0018445 prothoracicotrophic hormone activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018445 The action characteristic of prothoracicotrophic hormone, a peptide hormone that is secreted by the brain and, upon receptor binding, acts on the prothoracic gland to stimulate the release of ecdysone in insects. GO:0018444 translation release factor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0018444 peptide chain release factor|eukaryotic peptide chain release factor A heterodimeric complex involved in the release of a nascent polypeptide chain from a ribosome. CHEBI:138302 (12E)-labda-8(17),12,14-triene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138302 CHEBI:58699 L-methioninium (S)-S-oxide residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58699 CHEBI:138301 labda-7,13(16),14-triene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138301 CHEBI:58698 molybdopterin(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58698 GO:0018441 iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl L-serinyl octairon heptasulfide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018441 RESID:AA0300 iron incorporation into iron-sulphur cluster via hexakis-L-cysteinyl L-serinyl octairon heptasulphide The incorporation of iron into a 8Fe-7S iron-sulfur cluster via hexakis-L-cysteinyl L-serinyl octairon heptasulfide, found in nitrogenase. CHEBI:58697 (2R,4S)-2,4-diazaniumylpentanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58697 CHEBI:138300 2-hydroxytetradecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138300 GO:0018440 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018440 CHEBI:58696 flaviolin-2-olate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58696 CHEBI:58684 3-epi-3-hydroxy-2'-deoxymugineate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58684 CHEBI:138317 N-terminal N,N,N-trimethyl-L-seryl-L-prolyl-L-lysyl(2+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138317 CHEBI:58683 3-sulfonatolactate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58683 CHEBI:138316 N-terminal N,N-dimethyl-L-seryl-L-prolyl-L-lysyl(2+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138316 CHEBI:58682 6-hydroxypseudooxynicotinium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58682 CHEBI:138315 N-terminal N,N,N-trimethyl-L-alanyl-L-prolyl-L-lysyl(2+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138315 CHEBI:138314 S-allylsulfenic acid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138314 CHEBI:58681 5-phospho-beta-D-ribosylaminium(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58681 GO:0018458 isopiperitenol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018458 UM-BBD_reactionID:r0740|RHEA:20860|KEGG_REACTION:R03261|MetaCyc:ISOPIPERITENOL-DEHYDROGENASE-RXN|EC:1.1.1.223 (-)-trans-isopiperitenol:NAD+ oxidoreductase activity Catalysis of the reaction: (1S,6R)-isopiperitenol + NAD(+) = (6R)-isoperitenone + H(+) + NADH. CHEBI:58680 O-phosphonatooxy-D-serine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58680 GO:0018457 perillyl-alcohol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018457 MetaCyc:PERILLYL-ALCOHOL-DEHYDROGENASE-RXN|KEGG_REACTION:R03945|RHEA:10664|EC:1.1.1.144|UM-BBD_reactionID:r0729 perillyl-alcohol:NAD+ oxidoreductase activity|perillyl alcohol dehydrogenase activity Catalysis of the reaction: NAD(+) + perillyl alcohol = H(+) + NADH + perillyl aldehyde. CHEBI:138319 monoalk-1-enyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138319 GO:0018459 carveol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018459 RHEA:13629|MetaCyc:CARVEOL-DEHYDROGENASE-RXN|KEGG_REACTION:R03114|EC:1.1.1.243|UM-BBD_reactionID:r0714 (-)-trans-carveol:NADP+ oxidoreductase activity|(-)-trans-carveol dehydrogenase activity Catalysis of the reaction: (1S,5R)-carveol + NADP(+) = (R)-carvone + H(+) + NADPH. CHEBI:138318 N-terminal N,N-dimethyl-L-prolyl-L-prolyl-L-lysyl(2+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138318 GO:0018454 acetoacetyl-CoA reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018454 UM-BBD_reactionID:r0202|RHEA:22256|EC:1.1.1.36|MetaCyc:RXN-7698 NADPH:acetoacetyl-CoA reductase activity|(R)-3-hydroxyacyl-CoA dehydrogenase activity|(R)-3-hydroxyacyl-CoA:NADP+ oxidoreductase activity|NADP-linked acetoacetyl CoA reductase activity|short chain beta-ketoacetyl(acetoacetyl)-CoA reductase activity|D(-)-beta-hydroxybutyryl CoA-NADP oxidoreductase activity|beta-ketoacyl-CoA reductase|acetoacetyl coenzyme A reductase activity|D-3-hydroxyacyl-CoA reductase activity|hydroxyacyl coenzyme-A dehydrogenase activity Catalysis of the reaction: (R)-3-hydroxyacyl-CoA + NADP+ = 3-oxoacyl-CoA + NADPH + H+. GO:0018453 2-hydroxytetrahydrofuran dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018453 UM-BBD_reactionID:r0018 Catalysis of the reaction: 2-hydroxytetrahydrofuran = 2 H+ + 2 e- + butyrolactone. GO:0018456 aryl-alcohol dehydrogenase (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018456 EC:1.1.1.90|RHEA:12076|UM-BBD_enzymeID:e0019|MetaCyc:ARYL-ALCOHOL-DEHYDROGENASE-RXN benzyl alcohol dehydrogenase activity|aryl-alcohol:NAD+ oxidoreductase activity|p-hydroxybenzyl alcohol dehydrogenase activity Catalysis of the reaction: an aromatic alcohol + NAD+ = an aromatic aldehyde + NADH + H+. GO:0018455 alcohol dehydrogenase [NAD(P)+] activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018455 RHEA:10736|EC:1.1.1.71|UM-BBD_reactionID:r0172|MetaCyc:ALCOHOL-DEHYDROGENASE-NADP+-RXN alcohol:NAD(P)+ oxidoreductase activity|aldehyde reductase (NADPH/NADH) Catalysis of the reaction: an alcohol + NAD(P)+ = an aldehyde + NAD(P)H + H+. CHEBI:58689 (1R,6R)-2-(3-carboxylatopropanoyl)-6-hydroxycyclohexa-2,4-diene-1-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58689 GO:0018450 myrtenol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018450 UM-BBD_reactionID:r0710 Catalysis of the reaction: myrtenol + O2 + 2 H+ + 2 e- = 2 H2O + myrtenal. CHEBI:138313 (+)-kolavelool biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138313 CHEBI:58688 divinyl chlorophyllide a(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58688 CHEBI:58687 pheophorbide a(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58687 GO:0018452 5-exo-hydroxycamphor dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018452 MetaCyc:R542-RXN|EC:1.1.1.327|UM-BBD_reactionID:r0427|RHEA:32879 Catalysis of the reaction: 5-exo-hydroxycamphor + NAD+ = NADH + H+ + 2,5-diketocamphane. CHEBI:138311 (+)-kolavenyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138311 CHEBI:58686 chlorophyllide b(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58686 GO:0018451 epoxide dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018451 UM-BBD_reactionID:r0595 Catalysis of the reaction: ethene oxide + NAD+ + CoA-SH = NADH + H+ + acetyl-CoA. CHEBI:58685 3''-deamino-3''-oxonicotianaminium(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58685 CHEBI:138310 (-)-kolavenyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138310 CHEBI:20067 3-hydroxybutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20067 CHEBI:20060 3-hydroxy fatty acyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20060 PR:000029189 AKT kinase biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000029189 AKT|serine-threonine kinase Akt|PKB A protein that has a core domain composition consisting of a PH domain (Pfam:PF00169), Protein kinase domain (Pfam:PF00069) and a Protein kinase C terminal domain (Pfam:PF00433). Mammals have three genes encoding AKT1, AKT2 and AKT3. The second messenger phosphatidylinositol-3,4,5-trisphosphate [PIP(3)], product of phosphatidylinositol 3-kinase, acts largely through its role as a kinase activator. Binding of the pleckstrin domain to PIP(3) results in its targeting to the plasma membrane. Full activity is gained only after phosphorylation at two sites. CHEBI:58673 ADP-D-ribose 2'-phosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58673 GO:0018429 copper incorporation into copper-sulfur cluster via heptakis-L-histidino tetracopper mu4-sulfide hydroxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018429 RESID:AA0298 copper incorporation into copper-sulphur cluster via heptakis-L-histidino tetracopper mu4-sulphide hydroxide The incorporation of copper into a 4Cu-S copper-sulfur cluster via heptakis-L-histidino tetracopper mu4-sulfide hydroxide. GO:0018428 copper incorporation into copper-sulfur cluster biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018428 copper incorporation into copper-sulphur cluster The incorporation of copper into a copper-sulfur cluster. CHEBI:58672 L-2-aminoadipate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58672 CHEBI:58671 L-3-oxoalaninate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58671 CHEBI:58670 4-oxoprolinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58670 GO:0018425 O3-(N-acetylglucosamine-1-phosphoryl)-L-serine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018425 RESID:AA0296 O3-(N-acetylglucosamine-1-phosphoryl)-L-serine anabolism|O3-(N-acetylglucosamine-1-phosphoryl)-L-serine synthesis|O3-(N-acetylglucosamine-1-phosphoryl)-L-serine biosynthesis|O3-(N-acetylglucosamine-1-phosphoryl)-L-serine formation The chemical reactions and pathways resulting in the formation of O3-(N-acetylglucosamine-1-phosphoryl)-L-serine. The recovery of O-phosphorylserine from acid hydrolysates suggests N-acetylglucosamine-1-phosphate residues are esterified to peptidyl serines through phosphoester bonds. GO:0018424 peptidyl-glutamic acid poly-ADP-ribosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018424 RESID:AA0295 This modification produces peptidyl-glutamic acid poly-ADP-ribose found in a number of nuclear proteins under certain conditions including the repair of single strand DNA breaks. The activated form of the generating enzyme poly(ADP-ribose) polymerase is itself modified in this way. GO:0018427 copper incorporation into metallo-sulfur cluster biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018427 copper incorporation into metallo-sulphur cluster The incorporation of copper into a metallo-sulfur cluster. GO:0018426 O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018426 RESID:AA0297 O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine anabolism|O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine synthesis|O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine formation|O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine biosynthesis The chemical reactions and pathways resulting in the formation of O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine. The polypeptide backbones of glycoproteins and mucin-like proteoglycans are extensively modified with a complex array of phosphoglycan chains that are linked to Ser/Thr-rich domains via a common Man-alpha1-PO4-Ser linkage. GO:0018421 UDP-N-acetylglucosamine:serine-protein N-acetylglucosamine-1-phosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018421 Catalysis of the transfer of N-acetylglucosamine-1-phosphate to a serine residue in a protein. GO:0018420 peptide cross-linking via N6-(L-isoaspartyl)-L-lysine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018420 RESID:AA0294 The formation of isopeptide bonds by ligation of peptidyl-lysine and peptidyl-asparagine residues. CHEBI:58679 17-O-acetylajmalinium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58679 GO:0018423 protein C-terminal leucine carboxyl O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018423 Reactome:R-HSA-8856945 protein phosphatase methyltransferase activity|protein-leucine O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + protein L-leucine = S-adenosyl-L-homocysteine + protein L-leucine methyl ester. This modification occurs only at the oxygen atoms of the free alpha carboxyl group of a leucine residue at the C-terminus of the protein. GO:0018422 GDP-mannose:serine-protein mannose-1-phosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018422 Catalysis of the transfer of mannose-1-phosphate to a serine residue in a protein. CHEBI:58678 luteolin 7-O-[(beta-D-glucosyluronate)-(1->2)-(beta-D-glucosiduronate)] 4'-O-beta-D-glucosiduronate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58678 CHEBI:58677 (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58677 CHEBI:58675 O-phosphonato-L-threonine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58675 CHEBI:58674 D-fructofuranose 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58674 CHEBI:20070 3-hydroxyhexanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_20070 CHEBI:44027 menaquinone-8 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_44027 GO:0018439 peptidyl-L-leucine methyl ester biosynthetic process from peptidyl-leucine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018439 RESID:AA0299 peptidyl-leucine esterification The modification of a C-terminal peptidyl-leucine to form peptidyl-L-leucine methyl ester. CHEBI:58661 trypanothione disulfide(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58661 CHEBI:58660 CDP-D-glucose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58660 CHEBI:58669 but-2-enoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58669 CHEBI:58668 (3S)-citramalyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58668 CHEBI:58667 (R)-1-pyrroline-5-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58667 CHEBI:58665 alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58665 OBO:GOCHE_50906 substance with role role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_50906 GO:0102111 gibberellin A20,2-oxoglutarate:oxygen oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102111 MetaCyc:RXN-113 Catalysis of the reaction: gibberellin A20 + 2-oxoglutarate + O2 <=> gibberellin A29 + succinate + carbon dioxide. GO:0102113 hypoxia-inducible factor-asparagine oxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102113 EC:1.14.11.30|RHEA:54268|MetaCyc:RXN-11321 Catalysis of the reaction: 2-oxoglutarate + O2 + a hypoxia inducible factor (HIF) alpha subunit = succinate + carbon dioxide + a (3S)-3-hydroxy-L-asparagine-HIF alpha subunit. GO:0102115 peptidoglycan asparagine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102115 MetaCyc:RXN-11338 Catalysis of the reaction: ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-gamma-D-isoglutaminyl-N-(beta-D-asparatyl)-L-lysyl-D-alanyl-D-alanine + ammonium + ATP = H+ + ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-gamma-D-isoglutaminyl-N-(beta-D-asparaginyl)-L-lysyl-D-alanyl-D-alanine + AMP + diphosphoric acid. GO:0102114 caprate dehydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102114 MetaCyc:RXN-11325 Catalysis of the reaction: decanoate + NADPH + O2 + H+ <=> 10-hydroxycaprate + NADP + H2O. GO:0102117 gibberellin A9 carboxyl methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102117 RHEA:36119|MetaCyc:RXN-11358|EC:2.1.1.275 Catalysis of the reaction: gibberellin A9 + S-adenosyl-L-methionine <=> gibberellin A9 methyl ester + S-adenosyl-L-homocysteine. PR:000005110 cholecystokinin biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000005110 CCK A protein that is a translation product of the human CCK gene or a 1:1 ortholog thereof. GO:0102116 laurate hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102116 MetaCyc:RXN-11340 Catalysis of the reaction: dodecanoate + NADPH + O2 + H+ <=> 11-hydroxylaurate + NADP + H2O. GO:0102119 gibberellin A20 carboxyl methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102119 MetaCyc:RXN-11360 Catalysis of the reaction: gibberellin A20 + S-adenosyl-L-methionine <=> gibberellin A20 methyl ester + S-adenosyl-L-homocysteine. GO:0102118 gibberellin A4 carboxyl methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102118 RHEA:36107|MetaCyc:RXN-11359|EC:2.1.1.276 Catalysis of the reaction: gibberellin A4 + S-adenosyl-L-methionine <=> gibberellin A4 methyl ester + S-adenosyl-L-homocysteine. GO:0102122 gibberellin A34 carboxyl methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102122 MetaCyc:RXN-11384|RHEA:36127 Catalysis of the reaction: gibberellin A34 + S-adenosyl-L-methionine = gibberellin A34 methyl ester + S-adenosyl-L-homocysteine. CHEBI:83628 N-acylammonia biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83628 GO:0102121 ceramidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102121 MetaCyc:RXN-11375|EC:3.5.1.23 Catalysis of the reaction: H2O + a ceramide = a sphingoid base + a fatty acid. CHEBI:83627 hexadecanoyl-AMP(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83627 GO:0102124 gibberellin A12 16alpha,17 epoxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102124 MetaCyc:RXN-11387 Catalysis of the reaction: gibberellin A12 + O2 + H+ + NAD(P)H <=> 16alpha, 17-epoxy gibberellin A12 + H2O + NAD(P). CHEBI:83626 tetradecanoyl-AMP(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83626 GO:0102123 gibberellin A4 16alpha,17 epoxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102123 MetaCyc:RXN-11385 Catalysis of the reaction: gibberellin A4 + O2 + H+ + NAD(P)H <=> 16alpha,17-epoxy gibberellin A4 + H2O + NAD(P). CHEBI:83625 O-adenyl-L-tyrosine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83625 GO:0102126 coniferyl aldehyde 5-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102126 MetaCyc:RXN-1142 Catalysis of the reaction: H+ + coniferyl aldehyde + NADPH + O2 <=> 5-hydroxy-coniferaldehyde + NADP + H2O. CHEBI:83624 O-adenyl-L-tyrosine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83624 GO:0102125 gibberellin A9 16alpha,17 epoxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102125 MetaCyc:RXN-11388 Catalysis of the reaction: gibberellin A9 + O2 + H+ + NAD(P)H <=> 16alpha, 17-epoxy gibberellin A9 + H2O + NAD(P). CHEBI:83623 dodecanoyl-AMP(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83623 GO:0102128 chalcone synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102128 MetaCyc:RXN-11468 Catalysis of the reaction: 4-dihydrocoumaroyl-CoA + 3 malonyl-CoA + 3 H+ = phloretin + 4 coenzyme A + 3 carbon dioxide. CHEBI:83622 fatty acyl-AMP(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83622 GO:0102127 8-oxoguanine deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102127 EC:3.5.4.32|MetaCyc:RXN-11455|RHEA:32067 Catalysis of the reaction: H+ + 7,8-dihydro-8-oxoguanine + H2O <=> 7,9-dihydro-1H-purine-2,6,8(3H)-trione + ammonium. CHEBI:83621 fatty acyl-AMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83621 PR:000020737 beta-nerve growth factor proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000020737 NGF/ClvPrd A beta-nerve growth factor that has been processed by proteolytic cleavage. PR:000019751 pro-epidermal growth factor proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000019751 EGF/ClvPrd A pro-epidermal growth factor that has been processed by proteolytic cleavage. PR:000020722 NEDD8 protein proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000020722 NEDD8/ClvPrd A NEDD8 protein that has been processed by proteolytic cleavage. GO:0102131 3-oxo-glutaryl-[acp] methyl ester reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102131 EC:1.1.1.100|MetaCyc:RXN-11476 Catalysis of the reaction: NADP + a 3R-hydroxyglutaryl-[acp] methyl ester <=> NADPH + H+ + a 3-oxo-glutaryl-[acp] methyl ester. GO:0102130 malonyl-CoA methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102130 RHEA:17105|EC:2.1.1.197|MetaCyc:RXN-11475 Catalysis of the reaction: S-adenosyl-L-methionine + a malonyl-[acp] = S-adenosyl-L-homocysteine + a malonyl-[acp] methyl ester. GO:0102133 limonene hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102133 MetaCyc:RXN-11493 Catalysis of the reaction: (4R)-limonene + O2 + NADH + H+ <=> (4R)-perillyl alcohol + NAD + H2O. GO:0102132 3-oxo-pimeloyl-[acp] methyl ester reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102132 MetaCyc:RXN-11480|EC:1.1.1.100 Catalysis of the reaction: NADP + a 3R-hydroxypimeloyl-[acp] methyl ester <=> NADPH + H+ + a 3-oxo-pimeloyl-[acp] methyl ester. GO:0102135 (22S)-22-hydroxy-campest-4-en-3-one C-23 hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102135 MetaCyc:RXN-11530 Catalysis of the reaction: H+ + (22S)-22-hydroxycampest-4-en-3-one + NADPH + O2 <=> (22R,23R)-22,23-dihydroxy-campest-4-en-3-one + NADP + H2O. OBO:cl#has_completed has_completed biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/cl#has_completed has_completed GO:0102134 (22S)-22-hydroxy-campesterol C-23 hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102134 MetaCyc:RXN-11529 Catalysis of the reaction: H+ + (22S)-22-hydroxycampesterol + NADPH + O2 <=> (22R,23R)-22,23-dihydroxycampesterol + NADP + H2O. GO:0102137 7-oxateasterone synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102137 MetaCyc:RXN-11537 Catalysis of the reaction: H+ + teasterone + NADPH + O2 <=> 7-oxateasterone + NADP + H2O. GO:0102136 3-epi-6-deoxocathasterone C-23 hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102136 RHEA:27321|MetaCyc:RXN-11531|EC:1.14.14.147 Catalysis of the reaction: H+ + 3-epi-6-deoxocathasterone + reduced (NADPH-hemoprotein reducdtase) + O2 = 6=deoxotyphasterol + oxidized (NADPH-hemoprotein reductase) + H2O. GO:0102139 2-hydroxy-6-oxo-6-(2'-aminophenyl)-hexa-2,4dienoate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102139 EC:3.7.1.13|RHEA:27870|MetaCyc:RXN-11543 Catalysis of the reaction: (2E,4E)-6-(2-aminophenyl)-2-hydroxy-6-oxohexa-2,4-dienoate + H2O <=> H+ + anthranilate + (2E)-2-hydroxypenta-2,4-dienoate. GO:0102138 7-oxatyphasterol synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102138 MetaCyc:RXN-11538 Catalysis of the reaction: H+ + typhasterol + NADPH + O2 <=> 7-oxatyphasterol + NADP + H2O. GO:0102140 heparan sulfate N-deacetylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102140 MetaCyc:RXN-11557 Catalysis of the reaction: H2O + [heparan sulfate]-N-acetyl-alpha-D-glucosamine = acetate + H+ + [heparan sulfate]-alpha-D-glucosamine. GO:0102142 [dermatan sulfate]-L-iduronyl 2-Osulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102142 MetaCyc:RXN-11561 Catalysis of the reaction: 3'-phosphonato-5'-adenylyl sulfate + [dermatan]-alpha-L-iduronate <=> adenosine 3',5'-bismonophosphate + [dermatan-sulfate]-2-O-sulfo-alpha-L-iduronate. GO:0102141 [chondroitin sulfate]-D-glucuronyl 2-O-sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102141 MetaCyc:RXN-11560 Catalysis of the reaction: 3'-phosphonato-5'-adenylyl sulfate + [chondroitin-sulfate]-beta-D-glucuronate = adenosine 3',5'-bismonophosphate + [chondroitin-sulfate]-2-O-sulfo-beta-D-glucuronate. GO:0102144 carboxyspermidine dehydrogenase II activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102144 MetaCyc:RXN-11566|RHEA:34111 Catalysis of the reaction: carboxyspermidine + H2O + NADP <=> L-aspartic acid 4-semialdehyde betaine + 1,4-butanediammonium + NADPH + H+. GO:0102143 carboxynorspermidine dehydrogenase I activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102143 MetaCyc:RXN-11565|RHEA:34115 Catalysis of the reaction: carboxynorspermidine + NADP + H2O <=> L-aspartic acid 4-semialdehyde betaine + trimethylenediaminium + NADPH + H+. GO:0102146 tricetin O-methytransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102146 RHEA:27493|MetaCyc:RXN-11582 Catalysis of the reaction: tricetin + S-adenosyl-L-methionine = H+ + 3'-O-methyltricetin + S-adenosyl-L-homocysteine. GO:0102145 (3R)-(E)-nerolidol synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102145 MetaCyc:RXN-11575|EC:4.2.3.49|RHEA:27534 Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + H2O <=> (3R,6E)-nerolidol + diphosphoric acid. GO:0043401 steroid hormone mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043401 steroid hormone mediated signalling A series of molecular signals mediated by a steroid hormone binding to a receptor. GO:0102148 N-acetyl-beta-D-galactosaminidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102148 MetaCyc:RXN-11622|EC:3.2.1.52 Catalysis of the reaction: H2O + an N-acetyl-beta-D-galactosalaminyl-[glycan] = N-acetyl-beta-D-galactosamine + a glycan. GO:0043400 cortisol secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043400 hydrocortisone secretion The regulated release of cortisol, a steroid hormone that in humans is the major circulating hormone of the cortex, or outer layer, of the adrenal gland. GO:0102147 3'-O-methyltricetin O methyl transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102147 RHEA:27497|MetaCyc:RXN-11583 Catalysis of the reaction: S-adenosyl-L-methionine + 3'-O-methyltricetin = H+ + S-adenosyl-L-homocysteine + 3',5'-di-O-methyltricetin. GO:0102149 farnesylcysteine lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102149 MetaCyc:RXN-11623|EC:1.8.3.6|RHEA:30231 Catalysis of the reaction: S-[(2E,6E)-farnesyl]-L-cysteine + O2 + H2O <=> (2-trans,6-trans)-farnesal + L-cysteine + hydrogen peroxide. CHEBI:83641 juvenile hormone I biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83641 GO:0043407 negative regulation of MAP kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043407 down regulation of MAPK activity|negative regulation of mitogen-activated protein kinase activity|downregulation of MAPK activity|down-regulation of MAPK activity|inhibition of MAPK activity|negative regulation of mitogen activated protein kinase activity Any process that stops, prevents, or reduces the frequency, rate or extent of MAP kinase activity. GO:0043406 positive regulation of MAP kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043406 upregulation of MAPK activity|positive regulation of mitogen-activated protein kinase activity|up regulation of MAPK activity|stimulation of MAPK activity|positive regulation of mitogen activated protein kinase activity|up-regulation of MAPK activity Any process that activates or increases the frequency, rate or extent of MAP kinase activity. GO:0043409 negative regulation of MAPK cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043409 negative regulation of mitogen-activated protein kinase kinase kinase cascade|down regulation of MAPKKK cascade|inhibition of MAPKKK cascade|negative regulation of MAP kinase cascade|downregulation of MAPK cascade|negative regulation of mitogen-activated protein kinase cascade|down regulation of MAPK cascade|inhibition of MAPK cascade|negative regulation of mitogen activated protein kinase kinase kinase cascade|down-regulation of MAPKKK cascade|negative regulation of mitogen activated protein kinase cascade|negative regulation of MAP kinase kinase kinase cascade|downregulation of MAPKKK cascade|negative regulation of MAPKKK cascade|down-regulation of MAPK cascade Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the MAPKKK cascade. GO:0043408 regulation of MAPK cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043408 regulation of mitogen activated protein kinase cascade|regulation of MAP kinase kinase kinase cascade|regulation of MAPKKK cascade|regulation of mitogen-activated protein kinase kinase kinase cascade|regulation of MAP kinase cascade|regulation of mitogen-activated protein kinase cascade|regulation of mitogen activated protein kinase kinase kinase cascade Any process that modulates the frequency, rate or extent of signal transduction mediated by the MAP kinase (MAPK) cascade. GO:0043403 skeletal muscle tissue regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043403 myofiber turnover The regrowth of skeletal muscle tissue to repair injured or damaged muscle fibers in the postnatal stage. GO:0043402 glucocorticoid mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043402 glucocorticoid mediated signalling A series of molecular signals mediated by the detection of a glucocorticoid hormone. GO:0043405 regulation of MAP kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043405 regulation of mitogen activated protein kinase activity|Regulation of MAPK activity|regulation of mitogen-activated protein kinase activity Any process that modulates the frequency, rate or extent of MAP kinase activity. GO:0043404 corticotropin-releasing hormone receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043404 corticotropin-releasing factor receptor activity|adrenocorticotropin-releasing hormone receptor activity|CRH receptor activity|CRF receptor activity Combining with corticotropin-releasing hormone and transmitting the signal to initiate a change in cell activity. PR:000020789 neuropeptide Y proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000020789 NPY/ClvPrd A neuropeptide Y that has been processed by proteolytic cleavage. PR:000019798 erythropoietin proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000019798 EPO/ClvPrd An erythropoietin that has been processed by proteolytic cleavage. CHEBI:138393 7-oxotaurodeoxycholic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138393 CHEBI:138391 7-oxoglycolithocholic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138391 CHEBI:138390 EC 1.1.1.159 (7alpha-hydroxysteroid dehydrogenase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138390 GO:0043410 positive regulation of MAPK cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043410 activation of MAPK cascade|up-regulation of MAPK cascade|stimulation of MAPK cascade|up regulation of MAPKKK cascade|positive regulation of MAP kinase kinase kinase cascade|positive regulation of MAPKKK cascade|positive regulation of mitogen-activated protein kinase kinase kinase cascade|upregulation of MAPKKK cascade|positive regulation of MAP kinase cascade|stimulation of MAPKKK cascade|up-regulation of MAPKKK cascade|positive regulation of mitogen-activated protein kinase cascade|activation of MAPKKK cascade|upregulation of MAPK cascade|positive regulation of mitogen activated protein kinase kinase kinase cascade Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade. GO:0043412 macromolecule modification biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0043412 The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties. GO:0043411 obsolete myopalladin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043411 myopalladin binding OBSOLETE. Interacting selectively and non-covalently with myopalladin, a myofibrillar protein with titin-like Ig domains. GO:0043418 homocysteine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043418 homocysteine degradation|homocysteine breakdown|homocysteine catabolism The chemical reactions and pathways resulting in the breakdown of homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid. GO:0043417 negative regulation of skeletal muscle tissue regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043417 down-regulation of skeletal muscle regeneration|downregulation of skeletal muscle regeneration|down regulation of skeletal muscle regeneration|inhibition of skeletal muscle regeneration Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle regeneration. UBERON_CORE:transitively_proximally_connected_to transitively proximally connected to biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/uberon/core#transitively_proximally_connected_to transitively_proximally_connected_to . GO:0043419 urea catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043419 urea decomposition|urea degradation|urea breakdown|urea catabolism The chemical reactions and pathways resulting in the breakdown of urea, the water soluble compound O=C-(NH2)2. GO:0043414 macromolecule methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043414 The covalent attachment of a methyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule. GO:0043413 macromolecule glycosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043413 The covalent attachment of a glycosyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule. GO:0043416 regulation of skeletal muscle tissue regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043416 Any process that modulates the frequency, rate or extent of skeletal muscle. GO:0043415 positive regulation of skeletal muscle tissue regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043415 upregulation of skeletal muscle regeneration|stimulation of skeletal muscle regeneration|activation of skeletal muscle regeneration|up-regulation of skeletal muscle regeneration|up regulation of skeletal muscle regeneration Any process that activates or increase the rate of skeletal muscle regeneration. CHEBI:138386 TDP-alpha-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138386 CHEBI:138385 N(omega)-(2'-phospho-ADP-D-ribosyl)-L-arginine(3-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138385 CHEBI:138384 7-oxotaurolithocholic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138384 CHEBI:138383 (4S,7R)-7-isopropyl-4-methyloxepan-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138383 CHEBI:138389 7,12-dioxolithocholic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138389 CHEBI:138388 4-methylpent-3-en-1-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138388 PR:000020775 atrial natriuretic factor proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000020775 NPPA/ClvPrd An atrial natriuretic factor that has been processed by proteolytic cleavage. GO:0043421 anthranilate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043421 MetaCyc:2AMINOBENZDEG-PWY ortho-aminobenzoic acid catabolism|anthranilic acid catabolic process|2-aminobenzoate catabolism|anthranilate catabolism|2-aminobenzoate degradation|anthranilate degradation|2-aminobenzoate breakdown|2-aminobenzoate catabolic process|anthranilic acid catabolism|anthranilate breakdown|ortho-aminobenzoic acid catabolic process The chemical reactions and pathways resulting in the breakdown of anthranilate (2-aminobenzoate). GO:0043420 anthranilate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043420 UM-BBD_pathwayID:abz2 anthranilic acid metabolism|anthranilic acid metabolic process|ortho-aminobenzoic acid metabolism|2-aminobenzoate metabolic process|anthranilate metabolism|ortho-aminobenzoic acid metabolic process|2-aminobenzoate metabolism The chemical reactions and pathways involving anthranilate (2-aminobenzoate). GO:0043423 3-phosphoinositide-dependent protein kinase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043423 phosphatidylinositol-3-phosphate-dependent protein kinase binding Interacting selectively and non-covalently with a 3-phosphoinositide-dependent protein kinase. GO:0043422 protein kinase B binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043422 PKB binding|Akt binding Interacting selectively and non-covalently with protein kinase B, an intracellular kinase that is important in regulating glucose metabolism. CHEBI:83665 lysidine monophosphate zwitterion residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83665 CHEBI:83664 lysine monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83664 GO:0043429 2-nonaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043429 2-nonaprenyl-6-methoxy-1,4-benzoquinone methylase activity Catalysis of the reaction: 2-nonaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine. CHEBI:83662 lysidine monophosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83662 GO:0043428 2-heptaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043428 MetaCyc:RXN-9227|RHEA:44756 2-heptaprenyl-6-methoxy-1,4-benzoquinone methylase activity Catalysis of the reaction: 2-heptaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-heptaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine. CHEBI:83661 lysidine monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83661 GO:0043425 bHLH transcription factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043425 Interacting selectively and non-covalently with any of the basic Helix-Loop-Helix (bHLH) superfamily of transcription factors, important regulatory components in transcriptional networks of many developmental pathways. GO:0043424 protein histidine kinase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043424 protein-histidine kinase binding|histidine-protein kinase binding|histidine kinase binding Interacting selectively and non-covalently with protein histidine kinase. GO:0043427 carbon fixation by 3-hydroxypropionate cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043427 3-hydroxypropionate pathway|3-hydroxypropionate cycle|hydroxypropionate pathway|hydroxypropionate cycle An autotrophic carbon dioxide fixation pathway by which two molecules of carbon dioxide are fixed to form glyoxylate. Acetyl coenzyme A (acetyl-CoA) is assumed to be converted to malate, and two CO2 molecules are thereby fixed. Malyl-CoA is thought to be cleaved to acetyl-CoA, the starting molecule, and glyoxylate, the carbon fixation product. GO:0043426 MRF binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043426 MyoD binding|Myf5 binding|Mrf4 binding|myogenin binding Interacting selectively and non-covalently with Myogenic Regulatory Factor (MRF), a member of the basic Helix-Loop-Helix (bHLH) superfamily of transcription factors. CHEBI:138397 octahydronaphthalenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138397 CHEBI:138396 OPC8-CoA (4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138396 CHEBI:138394 7-oxoglycodeoxycholic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138394 CHEBI:138399 7beta-hydroxy-3,12-dioxo-5beta-cholanic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138399 CHEBI:138398 (15Z)-12-oxophyto-10,15-dienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138398 CHEBI:138371 beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138371 CHEBI:138370 N(6)-(gamma-glutamyl)lysine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138370 GO:0043432 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043432 GO:0043431 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043431 MetaCyc:2.1.1.64-RXN 3-demethylubiquinone-9 3-methyltransferase activity|2-octaprenyl-6-hydroxy phenol methylase activity Catalysis of the reaction: 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol + S-adenosyl-L-methionine = ubiquinol + S-adenosyl-L-homocysteine. GO:0043434 response to peptide hormone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043434 response to polypeptide hormone stimulus|response to peptide hormone stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals. GO:0043433 negative regulation of DNA-binding transcription factor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043433 negative regulation of thyroid hormone receptor activity|down-regulation of transcription factor activity|negative regulation of transcription factor activity|negative regulation of androgen receptor activity|negative regulation of DNA binding transcription factor activity|negative regulation of sequence-specific DNA binding transcription factor activity|inhibition of transcription factor activity|down regulation of transcription factor activity|downregulation of transcription factor activity Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription. CHEBI:83677 12-PAHSA(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83677 GO:0043430 2-decaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043430 RHEA:44764|Reactome:R-HSA-2162188 2-decaprenyl-6-methoxy-1,4-benzoquinone methylase activity Catalysis of the reaction: 2-decaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-decaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine. GO:0043439 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043439 CHEBI:83670 9-PAHSA(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83670 CHEBI:138369 [4)-beta-D-GlcA-(1->4)-beta-D-GlcA2(or 3)Ac-(1->4)-beta-D-Glc-(1->4)-[(R)-4,6-CH3(COO(-))C-beta-D-Gal3(or 2)OHb-(1->3)-beta-D-Glc-(1->4)-beta-D-Glc-(1->4)-beta-D-Glc-(1->6)]-alpha-DGlc2(or 3)Ac-(1->]n biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138369 GO:0043436 oxoacid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043436 oxo acid metabolic process|ketoacid metabolism|ketoacid metabolic process|oxo acid metabolism|keto acid metabolic process|oxoacid metabolism|keto acid metabolism The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons). GO:0043435 response to corticotropin-releasing hormone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043435 response to CRF stimulus|response to CRH stimulus|response to corticotropin-releasing factor stimulus|response to corticoliberin stimulus|response to corticotropin-releasing hormone stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticotropin-releasing hormone stimulus. Corticotropin-releasing hormone is a peptide hormone involved in the stress response. GO:0043438 acetoacetic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043438 beta-ketobutyric acid metabolic process|diacetic acid metabolism|beta ketobutyric acid metabolism|3-oxobutanoic acid metabolic process|acetoacetic acid metabolism|3-oxobutanoic acid metabolism|beta ketobutyric acid metabolic process|diacetic acid metabolic process|beta-ketobutyric acid metabolism|3-oxobutanoate metabolic process|acetoacetate metabolic process|acetoacetate metabolism|3-oxobutanoate metabolism The chemical reactions and pathways involving acetoacetic acid, 3-oxobutanoic acid; the empirical formula is C4H6O3 or CH3COCH2COOH. GO:0043437 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043437 CHEBI:138363 (4R,7S)-7-hydroxy-4-isopropenyl-7-methyloxepan-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138363 CHEBI:138362 (4S,7R)-7-hydroxy-4-isopropenyl-7-methyloxepan-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138362 CHEBI:138361 2-[(5Z,13E,15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dien-1-oyl]-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138361 CHEBI:138366 bile acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138366 CHEBI:138365 allo-bile acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138365 GO:0102100 mycothiol-arsenate ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102100 EC:2.8.4.2|MetaCyc:RXN-11187|RHEA:27349 Catalysis of the reaction: arsenate + mycothiol <=> mycothiol-arsenate conjugate + H2O. GO:0102102 homocarnosine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102102 EC:6.3.2.11|RHEA:59568|MetaCyc:RXN-11222 Catalysis of the reaction: gamma-aminobutyric acid + L-histidine + ATP = H+ + homocarnosine + ADP + hydrogenphosphate. GO:0043443 acetone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043443 dimethyl ketone metabolism|2-propanone metabolic process|propan-2-one metabolism|acetone metabolism|propan-2-one metabolic process|2-propanone metabolism|dimethyl ketone metabolic process The chemical reactions and pathways involving acetone, propan-2-one. GO:0102101 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0102101 GO:0043442 acetoacetic acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043442 acetoacetic acid catabolism|acetoacetic acid degradation|acetoacetic acid breakdown The chemical reactions and pathways resulting in the breakdown of acetoacetic acid, a beta-keto acid of the keto acid group, empirical formula is C4H6O3 or CH3COCH2COOH. GO:0043445 acetone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043445 acetone synthesis|acetone formation|dimethyl ketone biosynthesis|dimethyl ketone biosynthetic process|propan-2-one biosynthesis|propan-2-one biosynthetic process|acetone biosynthesis|2-propanone biosynthetic process|2-propanone biosynthesis|acetone anabolism The chemical reactions and pathways resulting in the formation of acetone, propan-2-one. GO:0102104 demethoxycurcumin synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102104 MetaCyc:RXN-11224 Catalysis of the reaction: (4-coumaroyl)acetyl-CoA + feruloyl-CoA + H2O <=> demethoxycurcumin + 2 coenzyme A + carbon dioxide. GO:0043444 acetone catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043444 propan-2-one catabolic process|dimethyl ketone catabolism|dimethyl ketone catabolic process|propan-2-one catabolism|acetone degradation|acetone catabolism|2-propanone catabolic process|acetone breakdown|2-propanone catabolism The chemical reactions and pathways resulting in the breakdown of acetone, propan-2-one. GO:0102103 demethoxycurcumin synthase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102103 EC:2.3.1.219|MetaCyc:RXN-11223|RHEA:35119 Catalysis of the reaction: (4-coumaroyl)acetyl-CoA + 4-coumaryl-CoA + H2O <=> bisdemethoxycurcumin + 2 coenzyme A + carbon dioxide. GO:0102106 curcumin synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102106 EC:2.3.1.217|MetaCyc:RXN-11226|RHEA:34823 Catalysis of the reaction: feruloylacetyl-CoA + feruloyl-CoA(4-) + H2O <=> curcumin + 2 coenzyme A(4-) + carbon dioxide. GO:0102105 demethoxycurcumin synthase activity from feruloylacetyl-CoA biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102105 EC:2.3.1.219|MetaCyc:RXN-11225|RHEA:35139 Catalysis of the reaction: feruloylacetyl-CoA + 4-coumaryl-CoA + H2O = demethoxycurcumin + 2 coenzyme A + carbon dioxide. GO:0043441 acetoacetic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043441 acetoacetic acid synthesis|acetoacetic acid formation|acetoacetic acid biosynthesis|acetoacetic acid anabolism The chemical reactions and pathways resulting in the formation of acetoacetic acid, a beta-keto acid of the keto acid group, empirical formula is C4H6O3 or CH3COCH2COOH. GO:0043440 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043440 GO:0102109 tricaffeoyl spermidine O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102109 MetaCyc:RXN-11261 Catalysis of the reaction: tricaffeoyl spermidine + 3 S-adenosyl-L-methionine <=> 3 H+ + triferuloyl spermidine + 3 S-adenosyl-L-homocysteine. CHEBI:83683 N-terminal N-acetyl-L-alanine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83683 GO:0043447 alkane biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043447 alkane synthesis|alkane formation|alkane biosynthesis|alkane anabolism The chemical reactions and pathways resulting in the formation of an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2. GO:0043446 cellular alkane metabolic process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0043446 alkane metabolism The chemical reactions and pathways involving an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2, as carried out by individual cells. GO:0043449 cellular alkene metabolic process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0043449 alkene metabolism The chemical reactions and pathways involving an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n, as carried out by individual cells. GO:0043448 alkane catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043448 alkane degradation|alkane breakdown|alkane catabolism The chemical reactions and pathways resulting in the breakdown of an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2. CHEBI:138375 (1E)-2,6-dimethylhepta-1,5-dien-1-yl formate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138375 CHEBI:138374 N-(12-hydroxyjasmonyl)-L-alpha-amino acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138374 CHEBI:138373 4-methylpent-3-en-1-yl acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138373 OBO:GOCHE_25944 substance with pesticide role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_25944 CHEBI:138372 beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138372 CHEBI:138379 ursodeoxycholoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138379 CHEBI:138378 beta-muricholoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138378 CHEBI:138377 allodeoxycholoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138377 CHEBI:138376 allocholoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138376 GO:0102193 protein-ribulosamine 3-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102193 RHEA:48432|EC:2.7.1.172|MetaCyc:RXN-12003 Catalysis of the reaction: ATP + a [protein]-N6-D-ribulosyl-L-lysine <=> ADP + a [protein]-N6-(3-O-phospho-D-ribulosyl)-L-lysine. GO:0102192 neryl-diphosphate:isopentenyl-diphosphate cistransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102192 EC:2.5.1.92|MetaCyc:RXN-11973 Catalysis of the reaction: neryl diphosphate(3-) + isopentenyl diphosphate(3-) <=> diphosphoric acid + 2-cis,6-cis-farnesyl diphosphate(3-). GO:0102195 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--D-lysine ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102195 RHEA:25273|MetaCyc:RXN-12042|EC:6.3.2.37 Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamate + D-lysinium(1+) + ATP <=> UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-D-lysine + ADP + hydrogenphosphate + H+. GO:0102194 protein-fructosamine 3-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102194 RHEA:59832|EC:2.7.1.171|MetaCyc:RXN-12005 Catalysis of the reaction: ATP + a [protein]-N6-D-fructosyl-L-lysine <=> ADP + H+ + a [protein]-N6-(3-O-phospho-D-fructosyl)-L-lysine. GO:0102197 vinylacetate caboxylester hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102197 MetaCyc:RXN-12087 Catalysis of the reaction: but-3-enoate + H2O <=> allyl alcohol + formate. GO:0102196 cortisol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102196 MetaCyc:RXN-12085 Catalysis of the reaction: cortisol + NADP <=> cortisone + NADPH + H+. GO:0102199 nitric oxide reductase activity (NAD(P)H-dependent) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102199 MetaCyc:RXN-12112|EC:1.7.1.14 Catalysis of the reaction: dinitrogen oxide + H2O + NAD(P) = 2 nitric oxide + H+ + NAD(P)H. UBERON:0015030 pedal digit phalanx endochondral element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015030 pedal digit phalanx skeletal element|pedal digit phalanx element A pedal digit phalanx bone or its cartilage or pre-cartilage precursor. GO:0102198 L-idonate 5-dehydrogenase activity (NAD-dependent) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102198 RHEA:21172|EC:1.1.1.366|MetaCyc:RXN-12107 Catalysis of the reaction: L-idonate + NAD = 5-dehydro-D-gluconate + NADH + H+. UBERON:0015036 pedal digit metatarsal endochondral element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015036 pedal digit metatarsal element|pedal digit metatarsal skeletal element A pedal digit metatarsal bone or its cartilage or pre-cartilage precursor. CHEBI:222169 (S)-nipecotic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_222169 OBA:VT0000056 urine trait biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_VT0000056 The quality when measured in urine. UBERON:0015021 forelimb endochondral element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015021 forelimb skeletal element A forelimb bone or its cartilage or pre-cartilage precursor. UBERON:0015023 phalanx endochondral element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015023 phalanx element|phalanx skeletal element A phalanx bone or its cartilage or pre-cartilage precursor. UBERON:0015022 hindlimb endochondral element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015022 hindlimb bone skeletal element A hindlimb bone or its cartilage or pre-cartilage precursor. UBERON:0015024 manual digit phalanx endochondral element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015024 manual digit phalanx element|manual digit phalanx skeletal element A manual digit phalanx bone or its cartilage or pre-cartilage precursor. UBERON:0015019 rib endochondral element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015019 rib element|rib skeletal element A rib bone or its cartilage or pre-cartilage precursor. UBERON:0015013 fibula endochondral element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015013 fibula element|fibula skeletal element The major postaxial endochondral element in the posterior zeugopod[Phenoscape]. UBERON:0005691 4th arch mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005691 4th pharyngeal arch mesenchyme|4th branchial arch mesenchyme|pharyngeal arch 4 mesenchyme Mesenchyme that is part of a pharyngeal arch 4. UBERON:0005690 3rd arch mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005690 3rd pharyngeal arch mesenchyme|3rd branchial arch mesenchyme|pharyngeal arch 3 mesenchyme Mesenchyme that is part of a pharyngeal arch 3. UBERON:0015007 cervical vertebra endochondral element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015007 cervical vertebra skeletal element|cervical vertebra element A vertebral endochondral element in the cervical region of the vertebral column. UBERON:0015008 thoracic vertebra endochondral element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015008 thoracic vertebra skeletal element|thoracic vertebra element A vertebral endochondral element in the thoracic region of the vertebral column. UBERON:0015004 tibia endochondral element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015004 tibia skeletal element|tibia element The major preaxial endochondral element in the posterior zeugopod[Phenoscape]. CHEBI:10642 scyllo-inositol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_10642 UBERON:0005689 2nd arch mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005689 2nd branchial arch mesenchyme|pharyngeal arch 2 mesenchyme|2nd pharyngeal arch mesenchyme Mesenchyme that is part of a pharyngeal arch 2. UBERON:0005688 lens vesicle cavity biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005688 lens cavity|cavity of lens vesicle|cavity of lens An anatomical cavity that is part of a lens vesicle. UBERON:0005687 orbitosphenoid cartilage element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005687 sphenoid lesser wing cartilage element A orbitosphenoid endochondral element that is composed primarily of cartilage tissue. UBERON:0005686 caecum dorsal mesentery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005686 A dorsal mesentery that is part of a caecum. UBERON:0005685 midgut dorsal mesentery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005685 A dorsal mesentery that is part of a midgut. GO:0102151 3-oxo-myristate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102151 EC:4.1.1.56|MetaCyc:RXN-11669 Catalysis of the reaction: 3-oxo-myristate + H+ <=> 2-tridecanone + carbon dioxide. UBERON:0015078 proximal carpal endochondral element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015078 proximal carpal element|proximal carpal A proximal mesopodial endochondral element that is part of a forelimb. GO:0102150 3-oxo-myristoyl-CoA hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102150 MetaCyc:RXN-11668 Catalysis of the reaction: 3-oxotetradecanoyl-CoA + H2O <=> 3-oxo-myristate + coenzyme A + H+. GO:0102152 Delta12-linoleate epoxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102152 MetaCyc:RXN-11671 Catalysis of the reaction: H+ + 1-palmitoyl-2-linoleoyl-phosphatidylcholine + NADPH + O2 <=> 1-palmitoyl-2-vernoloyl-phosphatidylcholine + NADP + H2O. GO:0102155 S-sulfolactate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102155 MetaCyc:RXN-11689|EC:1.1.1.310|RHEA:28194 Catalysis of the reaction: (S)-3-sulfonatolactate + NAD <=> 3-sulfonatopyruvate(2-) + NADH + H+. GO:0102154 8C-naringenin dibenzoylmethane tautomer glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102154 MetaCyc:RXN-11685 Catalysis of the reaction: 2,4,4',6-tetrahydroxydibenzoylmethane + UDP-alpha-D-glucose <=> 8C-glucosyl-2-hydroxynaringenin + UDP + 2 H+. GO:0102157 (R)-sulfopropanediol 2-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102157 MetaCyc:RXN-11729 Catalysis of the reaction: (2R)-3-sulfopropanediol(1-) + NAD <=> 2-oxo-3-hydroxy-propane-1-sulfonate + NADH + H+. GO:0102156 2,5-DHBA UDP-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102156 MetaCyc:RXN-11705 Catalysis of the reaction: 2,5-dihydroxybenzoate + UDP-alpha-D-glucose <=> 2,5-dihydroxybenzoate 5-O-beta-D-glucoside + UDP + H+. GO:0102159 baicalein 7-O-glucuronosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102159 RHEA:28314|EC:2.4.1.253|MetaCyc:RXN-11755 Catalysis of the reaction: UDP-alpha-D-glucuronate + baicalein <=> H+ + UDP + baicalin. GO:0102158 very-long-chain 3-hydroxyacyl-CoA dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102158 RHEA:45812|EC:4.2.1.134|MetaCyc:RXN-11750 Catalysis of the reaction: a very-long-chain (3R)-3-hydroxyacyl-CoA = H2O + a very-long-chain trans-2,3-dehydroacyl-CoA. UBERON:0015079 proximal carpal cartilage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015079 A proximal carpal endochondral element that is composed primarily of cartilage tissue. NCBITaxon:7214 Drosophilidae organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_7214 pomace flies GO:0102160 cyanidin-3-O-glucoside 2-O-glucuronosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102160 RHEA:28258|EC:2.4.1.254|MetaCyc:RXN-11756 Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + UDP-alpha-D-glucuronate <=> H+ + cyanidin 3-O-beta-(2-O-beta-D-glucuronosyl)-beta-D-glucoside + UDP. UBERON:0015064 autopod cartilage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015064 A autopod endochondral element that is composed primarily of cartilage tissue. GO:0102162 all-trans-8'-apo-beta-carotenal 15,15'-oxygenase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102162 MetaCyc:RXN-11783|EC:1.13.11.75|RHEA:26385 Catalysis of the reaction: 8'-apo-beta,psi-caroten-8'-al + O2 <=> all-trans-retinal + 2,6-dimethylocta-2,4,6-trienedial. GO:0102161 copal-8-ol diphosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102161 MetaCyc:RXN-11772|RHEA:32703|EC:4.2.1.133 Catalysis of the reaction: copal-8-ol diphosphate <=> 2-trans,6-trans,10-trans-geranylgeranyl diphosphate + H2O. GO:0102164 2-heptyl-3-hydroxy-4(1H)-quinolone synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102164 EC:1.14.13.182|RHEA:37871|MetaCyc:RXN-11849 Catalysis of the reaction: 2-heptyl-4-quinolone + NADH + O2 + H+ <=> 2-heptyl-3-hydroxy-4-quinolone + NAD + H2O. UBERON:0015061 limb endochondral element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015061 limb bone endochondral element|limb bone skeletal element A limb bone or its cartilage or pre-cartilage precursor. GO:0102163 3-hydroxyacyl-CoA-acyl carrier protein transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102163 MetaCyc:RXN-11785 Catalysis of the reaction: coenzyme A + a (3R)-3-hydroxyacyl-[acyl-carrier protein] = a (3R)-3-hydroxyacyl-CoA + a holo-[acyl-carrier protein]. UBERON:0015060 sphenoid endochondral element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015060 sphenoid bone skeletal element|sphenoid element A sphenoid bone or its cartilage or pre-cartilage precursor. UBERON:0015063 autopod endochondral element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015063 A endochondral element that is part of a autopod region. GO:0102166 [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102166 MetaCyc:RXN-11891|RHEA:48892|EC:3.2.1.169 Catalysis of the reaction: H2O + an N-acetyl-alpha-D-glucosaminyl-L-threonine-[glycoprotein] <=> N-acetyl-alpha-D-glucosaminide + a [protein]-L-threonine. GO:0102165 (Z)-3-hexen-1-ol acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102165 MetaCyc:RXN-11852|EC:2.3.1.195|RHEA:28254 Catalysis of the reaction: acetyl-CoA + (Z)-hex-3-en-1-ol <=> (3Z)-hex-3-en-1-yl acetate + coenzyme A. NCBITaxon:7215 Drosophila organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_7215 Drosophila|fruit fly|fruit flies GO:0102168 5-methyl-phenazine-1-carboxylate N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102168 MetaCyc:RXN-11897|RHEA:49112 Catalysis of the reaction: phenazine-1-carboxylate + S-adenosyl-L-methionine <=> 5-methylphenazine-1-carboxylate + S-adenosyl-L-homocysteine. GO:0102167 [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102167 MetaCyc:RXN-11892|RHEA:48876|EC:3.2.1.169 Catalysis of the reaction: H2O + an N-acetyl-alpha-D-glucosaminyl-L-serine-[glycoprotein] <=> N-acetyl-alpha-D-glucosaminide + a [protein]-L-serine. GO:0102169 pyocyanin hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102169 MetaCyc:RXN-11898|RHEA:48976 Catalysis of the reaction: 5-methylphenazine-1-carboxylate + NADH + O2 + 2 H+ <=> pyocyanin + NAD + carbon dioxide + H2O. GO:0102171 DMNT synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102171 MetaCyc:RXN-11911|RHEA:55424 Catalysis of the reaction: H+ + (3S,6E)-nerolidol + NADPH + O2 <=> (E)-4,8-dimethyl-1,3,7-nonatriene + buten-2-one + NADP + 2 H2O. GO:0102170 5-epi-aristolochene-1,3-dihydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102170 MetaCyc:RXN-11908|RHEA:28226|EC:1.14.14.149 Catalysis of the reaction: (+)-5-epi-aristolochene + 2 NADPH + 2 H+ + 2 O2 <=> capsidiol + 2 NADP + 2 H2O. UBERON:0015053 humerus endochondral element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015053 humerus skeletal element|humerus element A humerus bone or its cartilage or pre-cartilage precursor. GO:0102173 24-methylenecycloartanol 4alpha-methyl oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102173 MetaCyc:RXN-11926|RHEA:58836 Catalysis of the reaction: 24-methylenecycloartanol + NADH + O2 + H+ <=> 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NAD + H2O. OBO:chebi#has_parent_hydride has parent hydride biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/chebi#has_parent_hydride GO:0102172 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol-4alpha-methyl oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102172 RHEA:58860|MetaCyc:RXN-11925 Catalysis of the reaction: 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NADH + O2 + H+ <=> 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NAD + 2 H2O. GO:0102175 3-beta-hydroxysteroid dehydrogenase/C4-decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102175 RHEA:34775|MetaCyc:RXN-11928 Catalysis of the reaction: a 3beta-hydroxysteroid-4alpha-carboxylate + NAD(+) = a 3-oxosteroid + CO2 + NADH. UBERON:0015050 tarsus endochondral element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015050 tarsus skeletal element|tarsus element A tarsus bone or its cartilage or pre-cartilage precursor. GO:0102174 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol-4alpha-methyl oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102174 RHEA:58864|MetaCyc:RXN-11927 Catalysis of the reaction: 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NADH + O2 <=> 4alpha-carboxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NAD + H2O. GO:0102177 24-methylenelophenol methyl oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102177 RHEA:58872|MetaCyc:RXN-11930 Catalysis of the reaction: 24-methylenelophenol + O2 + NADH + H+ <=> 4alpha-hydroxymethyl-ergosta-7,24(241)-dien-3beta-ol + NAD + H2O. UBERON:0015052 femur endochondral element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015052 femur skeletal element|femur element A femur bone or its cartilage or pre-cartilage precursor. GO:0102176 cycloeucalenone reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102176 MetaCyc:RXN-11929 Catalysis of the reaction: cycloeucalenone + NADPH + H+ <=> cycloeucalenol + NADP. GO:0102179 24-ethylidenelophenol 4alpha-methyl oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102179 MetaCyc:RXN-11935|RHEA:59032 Catalysis of the reaction: 24-ethylidenelophenol + NADH + O2 + H+ <=> 4alpha-hydroxymethyl-stigmasta-7,24(241)-dien-3beta-ol + NAD + H2O. CHEBI:10615 omega-hydroxy fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_10615 GO:0102178 4alpha-formyl-ergosta-7,24(241)-dien-3beta-ol-methyl oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102178 RHEA:58880|MetaCyc:RXN-11932 Catalysis of the reaction: 4alpha-formyl-ergosta-7,24(241)-dien-3beta-ol + O2 + NADH <=> 4alpha-carboxy-ergosta-7,24(241)-dien-3beta-ol + NAD + H2O. UBERON:0015057 scapula endochondral element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015057 scapula skeletal element|scapula element A scapula bone or its cartilage or pre-cartilage precursor. UBERON:0015059 orbitosphenoid endochondral element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015059 orbitosphenoid element|orbitosphenoid skeletal element A orbitosphenoid bone or its cartilage or pre-cartilage precursor. GO:0102180 4alpha-hydroxymethyl-stigmasta-7,24(241)-dien-3beta-ol-methyl oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102180 RHEA:59036|MetaCyc:RXN-11936 Catalysis of the reaction: 4alpha-hydroxymethyl-stigmasta-7,24(241)-dien-3beta-ol + NADH + O2 + H+ <=> 4alpha-formyl-stigmasta-7,24(241)-dien-3beta-ol + NAD + 2 H2O. GO:0102182 4alpha-carboxy-stigmasta-7,24(241)-dien-3beta-ol dehydrogenase/C4-decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102182 MetaCyc:RXN-11938 Catalysis of the reaction: 4alpha-carboxy-stigmasta-7,24(241)-dien-3beta-ol + NAD <=> avenastenone + NADH + carbon dioxide. UBERON:0015042 manual digit metacarpus endochondral element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015042 manual digit metacarpus element|manual digit metacarpus skeletal element A manual digit metacarpus bone or its cartilage or pre-cartilage precursor. GO:0102181 4alpha-formyl-stigmasta-7,24(241)-dien-3beta-ol-methyl oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102181 MetaCyc:RXN-11937|RHEA:59040 Catalysis of the reaction: 4alpha-formyl-stigmasta-7,24(241)-dien-3beta-ol + NADH + O2 <=> 4alpha-carboxy-stigmasta-7,24(241)-dien-3beta-ol + NAD + H2O. GO:0102184 cycloartenol 4alpha-methyl oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102184 MetaCyc:RXN-11946 Catalysis of the reaction: cycloartenol + NADH + O2 + H+ <=> 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NAD + H2O. GO:0102183 avenastenone reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102183 MetaCyc:RXN-11939 Catalysis of the reaction: avenastenone + NADPH + H+ <=> avenasterol + NADP. GO:0102186 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol-4alpha-methyl oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102186 MetaCyc:RXN-11948 Catalysis of the reaction: 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NADH(2-) + O2 <=> 4alpha-carboxy,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NAD(1-) + H2O. GO:0102185 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol-4alpha-methyl oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102185 MetaCyc:RXN-11947 Catalysis of the reaction: 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NADH(2-) + O2 + H+ <=> 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NAD(1-) + 2 H2O. GO:0102188 4alpha-methyl-5alpha-cholesta-7,24-dien-3beta-ol-4alpha-methyl oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102188 MetaCyc:RXN-11956 Catalysis of the reaction: 4alpha-methyl-5alpha-cholesta-7,24-dien-3beta-ol + O2 + NADH(2-) + H+ <=> 4alpha-hydroxymethyl-5alpha-cholesta-7,24-dien-3beta-ol + NAD(1-) + H2O. GO:0102187 4alpha-carboxy,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol dehydrogenase/C4-decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102187 MetaCyc:RXN-11949 Catalysis of the reaction: 4alpha-carboxy,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NAD(1-) <=> 4alpha,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3-one + NADH(2-) + carbon dioxide. GO:0102189 4alpha-hydroxymethyl-5alpha-cholesta-7,24-dien-3beta-ol-4alpha-methyl oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102189 MetaCyc:RXN-11957 Catalysis of the reaction: 4alpha-hydroxymethyl-5alpha-cholesta-7,24-dien-3beta-ol + O2 + NADH(2-) + H+ <=> 4alpha-formyl-5alpha-cholesta-7,24-dien-3beta-ol + NAD(1-) + 2 H2O. UBERON:0015049 carpus endochondral element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015049 carpus element|carpus skeletal element A carpus bone or its cartilage or pre-cartilage precursor. NCBITaxon:7203 Brachycera organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_7203 GO:0102191 4alpha-carboxy-5alpha-cholesta-7,24-dien-3beta-ol dehydrogenase/C4-decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102191 RHEA:59016|EC:1.1.1.418|MetaCyc:RXN-11959 Catalysis of the reaction: 4alpha-carboxy-5alpha-cholesta-7,24-dien-3beta-ol + NAD(1-) <=> 5alpha-cholesta-7,24-dien-3-one + NADH(2-) + carbon dioxide. GO:0102190 4alpha-formyl-5alpha-cholesta-7,24-dien-3beta-ol-4alpha-methyl oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102190 MetaCyc:RXN-11958 Catalysis of the reaction: 4alpha-formyl-5alpha-cholesta-7,24-dien-3beta-ol + O2 + NADH(2-) <=> 4alpha-carboxy-5alpha-cholesta-7,24-dien-3beta-ol + NAD(1-) + H2O. UBERON:0005629 vascular plexus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005629 plexus vasculosus A vascular network formed by frequent anastomoses between the blood vessels (arteries or veins) of a part. GO:0018407 peptidyl-thyronine iodination to form 3',3'',5'-triiodo-L-thyronine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018407 RESID:AA0177 peptidyl-thyronine iodination to form triiodothyronine The iodination of peptidyl-thyronine to form peptidyl-3',3'',5'-triiodo-L-thyronine (triiodothyronine). GO:0018406 protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018406 RESID:AA0217 protein amino acid C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan|protein amino acid C-linked mannosylation The glycosylation of a peptidyl-tryptophan residue by the transfer of alpha-mannopyranose from dolichyl-activated mannose to the indole ring. GO:0018409 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018409 GO:0018408 peptidyl-thyronine iodination to form 3',3'',5',5''-tetraiodo-L-thyronine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018408 RESID:AA0178 The iodination of peptidyl-thyronine to form peptidyl-3',3'',5',5''-tetraiodo-L-thyronine (L-thyroxine). GO:0018403 protein-dermatan sulfate linkage via dermatan 4-sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018403 RESID:AA0209 protein-dermatan sulphate linkage via dermatan 4-sulphate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine Dermatan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues. GO:0018402 protein-chondroitin sulfate linkage via chondroitin sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018402 RESID:AA0208 protein-chondroitin sulphate linkage via chondroitin sulphate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine Chondroitin sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues. CHEBI:34687 dibutyl phthalate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_34687 GO:0018405 protein-keratan sulfate linkage via keratan sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-threonine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018405 RESID:AA0247 protein-keratan sulphate linkage via keratan sulphate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-threonine Keratan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and threonine residues. GO:0018404 protein-heparan sulfate linkage via heparan sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018404 RESID:AA0210 protein-heparan sulphate linkage via heparan sulphate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine Heparan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues. CHEBI:58659 8(R)-HPODE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58659 UBERON:0005637 pyloric region epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005637 An epithelium that is part of a pylorus. UBERON:0005636 caecum epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005636 An epithelium that is part of a caecum. CHEBI:58658 alpha-D-galacturonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58658 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018401 RESID:AA0030 The modification of peptidyl-proline to form 4-hydroxy-L-proline; catalyzed by procollagen-proline,2-oxoglutarate-4-dioxygenase. GO:0018400 peptidyl-proline hydroxylation to 3-hydroxy-L-proline biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018400 RESID:AA0029 The modification of peptidyl-proline to form 3-hydroxy-L-proline; catalyzed by procollagen-proline 3-dioxygenase. CHEBI:58655 (S)-3-aminoisobutyric acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58655 UBERON:0005631 extraembryonic membrane biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005631 Intrinsic membrane that arises from embryonic germ layers and grow to surround the developing embryo. CHEBI:58652 N(omega)-phosphohypotaurocyamine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58652 CHEBI:20056 3-hydroxy-L-proline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20056 UBERON:0005619 secondary palatal shelf biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005619 lateral palatine process|palatal shelf|palatal shelves|palatine shelf|secondary palatal shelf The outgrowths of the embryonic maxillary prominences that come together during prenatal development to form the secondary palate UBERON:0005617 mesenteric vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005617 intestinal vein A vein that returns blood from the intestines. UBERON:0005616 mesenteric artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005616 Arteries which arise from the abdominal aorta and distribute to most of the intestines. CHEBI:58640 pelargonidin 3-O-(6-O-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside betaine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58640 GO:0018418 nickel incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018418 RESID:AA0 nickel incorporation into iron-sulphur cluster via tris-L-cysteinyl L-cysteine persulphido L-glutamato L-histidino L-serinyl nickel triiron disulphide trioxide The incorporation of nickel into a 3Fe-2S complex by tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide. GO:0018417 iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018417 RESID:AA0293 iron incorporation into iron-sulphur cluster via tris-L-cysteinyl L-cysteine persulphido L-glutamato L-histidino L-serinyl nickel triiron disulphide trioxide The incorporation of iron into a 3Fe-2S cluster by tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide. GO:0018419 protein catenane formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018419 The aggregation, arrangement and bonding together of a protein structure comprising two or more rings that are interlocked but not covalently joined; resembling the links of a chain. GO:0018414 nickel incorporation into metallo-sulfur cluster biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018414 nickel incorporation into metallo-sulphur cluster The incorporation of nickel into a metallo-sulfur cluster. GO:0018413 peptidyl-serine O-glucuronidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018413 RESID:AA0291 The O-glucuronidation of peptidyl-serine to form peptidyl-O3-D-glucuronyl-L-serine. GO:0018416 nickel incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018416 RESID:AA0292 nickel incorporation into iron-sulphur cluster via tris-L-cysteinyl L-cysteine persulphido bis-L-glutamato L-histidino nickel triiron disulphide trioxide The incorporation of nickel into a 3Fe-2S complex by tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide. GO:0018415 iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018415 RESID:AA0292 iron incorporation into iron-sulphur cluster via tris-L-cysteinyl L-cysteine persulphido bis-L-glutamato L-histidino nickel triiron disulphide trioxide The incorporation of iron into a 3Fe-2S cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide. UBERON:0005626 ventral mesogastrium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005626 foregut ventral mesentery Portion of ventral mesentery closest to the stomach. GO:0018410 C-terminal protein amino acid modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018410 peptide/protein carboxyl-terminal blocking|peptide or protein carboxyl-terminal blocking The alteration of the C-terminal amino acid residue in a protein. UBERON:0005625 tubotympanic recess lumen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005625 tubotympanic recess|tubotympanic recess space|tubotympanic recess cavity|cavity of tubotympanic recess The cavity formed by the tubotympanic recess epithelium. CHEBI:58647 amidinoproclavaminic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58647 GO:0018412 protein O-glucuronidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018412 protein amino acid O-glucuronidation The modification of a protein by glucuronidation on an amino acid oxygen atom. UBERON:0005624 suprarenal artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005624 adrenal artery Artery that supplies blood to the adrenal glands. GO:0018411 protein glucuronidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018411 protein amino acid glucuronidation The modification of a protein by amino acid glucuronidation. CHEBI:58645 D-allothreonine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58645 UBERON:0005623 semi-lunar valve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005623 semilunar valves|semilunar valve the valves that gate the flow of blood from the ventricles into the aorta and pulmonary trunk UBERON:0005622 right dorsal aorta biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005622 CHEBI:58644 p-coumaroylagmatine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58644 UBERON:0005620 primary palate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005620 primary palate|palatum primarium|primitive palate|processus palatinus medianus|primary palate process The part of the palate formed from the intermaxillary segment. CHEBI:58642 2,3-dihydroxy-trans-cinnamate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58642 CHEBI:58641 N,N-dimethylethanolamine phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58641 UBERON:0005609 iliac artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005609 Any of the arteries that arise from a bifurcation of the aorta supplying the pelvic or abdomen. Examples: Common iliac artery, External iliac artery, Internal iliac artery UBERON:0005607 hyaloid vascular plexus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005607 hyaloid vascular system CHEBI:58639 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58639 NCBITaxon:7227 Drosophila melanogaster organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_7227 fruit fly|Sophophora melanogaster UBERON:0005606 hyaloid cavity biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005606 CHEBI:58638 4'''-demalonylsalvianin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58638 CHEBI:58637 2-hydroxy-6-oxonona-2,4,7-trienedioate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58637 UBERON:0005614 lens anterior epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005614 anterior surface of lens|lens subcapsular epithelium|lens epithelium|subcapsular lens epithelium|anterior epithelium of lens vesicle A layer of cuboidal epithelial cells bounded anteriorly by the capsule of the lens and posteriorly by the lens cortex. CHEBI:58636 2-hydroxy-2,3-dihydrogenistein-7-olate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58636 CHEBI:58635 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58635 UBERON:0005613 left dorsal aorta biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005613 CHEBI:58633 L-homoserine lactone(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58633 CHEBI:58632 2,4-divinyl protochlorophyllide a(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58632 UBERON:0005610 iliac vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005610 pelvic vein Any of the three veins including the common, external and internal iliac veins. CHEBI:58630 N-methylanthraniloyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58630 CHEBI:19062 1-methylguanosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_19062 CHEBI:58629 N-formyl-L-kynurenine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58629 CHEBI:58628 5-diphospho-1D-myo-inositol pentakisphosphate(13-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58628 CHEBI:58627 gibberellin A12(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58627 UBERON:0005604 extrahepatic part of hepatic duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005604 hepatic duct extrahepatic part|extrahepatic part of the hepatic duct UBERON:0005602 dorsal mesogastrium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005602 dorsal mesentery The portion of mesentery attached to the greater curvature of the stomach is named the dorsal mesentery (or dorsal mesogastrium, when referring to the portion at the stomach), and the part which suspends the colon is termed the mesocolon. The dorsal mesogastrium develops into the greater omentum. CHEBI:58622 5alpha,9beta,10alpha-labda-8(20),13-dien-15-yl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58622 CHEBI:58621 dehydroabietate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58621 CHEBI:58619 S-alkyl thiosulfate anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58619 CHEBI:58618 hydrogenselenophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58618 CHEBI:58616 2-methyl-4-oxo-1,4-dihydroquinolin-3-olate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58616 UBERON:0005673 left lung endothelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005673 An endothelium that is part of a left lung. UBERON:0005672 right lung endothelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005672 An endothelium that is part of a right lung. CHEBI:58614 2,5-diamino-4-hydroxy-6-(5-phosphonatoribosylamino)pyrimidine(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58614 CHEBI:58613 1-(2-carboxylatophenylamino)-1-deoxy-D-ribulose 5-phosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58613 CHEBI:58612 (+-)-5-[3-(tert-butylammonio)-2-hydroxypropoxy]-3,4-dihydronaphthalen-1(2H)-one(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58612 CHEBI:58611 (+-)-5-[3-(tert-butylammonio)-2-hydroxypropoxy]-1,2,3,4-tetrahydro-1-naphthol(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58611 UBERON:0005677 caecum mesentery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005677 A mesentery that is part of a caecum. CHEBI:58610 nocardicin E(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58610 CHEBI:20012 3-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20012 CHEBI:58609 D-2-ammoniohexano-6-lactam biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58609 CHEBI:58608 1,2-diacyl-sn-glycerol 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58608 CHEBI:58607 3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58607 CHEBI:20013 3-epi-3-hydroxymugineic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20013 CHEBI:58606 synephrinium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58606 CHEBI:20016 3-ethylcatechols biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20016 CHEBI:58605 3''-adenylylstreptomycin(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58605 CHEBI:10668 tRNA precursor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_10668 UBERON:0005662 4th arch ectoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005662 4th pharyngeal arch ectoderm An ectoderm that is part of a pharyngeal arch 4. CHEBI:2024 5-acetamidopentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_2024 UBERON:0005661 3rd arch ectoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005661 3rd pharyngeal arch ectoderm An ectoderm that is part of a pharyngeal arch 3. UBERON:0005660 2nd arch ectoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005660 2nd pharyngeal arch ectoderm An ectoderm that is part of a pharyngeal arch 2. CHEBI:58604 L-mimosine(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58604 UBERON:0005669 peritoneal cavity mesothelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005669 mesothelium of peritoneum|peritoneum|peritoneum mesothelium|mesothelium of peritoneal component|peritoneal mesothelium A mesothelium that is part of a peritoneal cavity. CHEBI:58603 lipid IVA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58603 CHEBI:58602 D-mannosyl undecaprenyl phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58602 CHEBI:58601 alpha-D-glucose 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58601 UBERON:0005667 connecting stalk mesoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005667 CHEBI:58600 N(tele)-methylhistaminium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58600 UBERON:0005666 4th arch endoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005666 4th pharyngeal arch endoderm An endoderm that is part of a pharyngeal arch 4. UBERON:0005665 3rd arch endoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005665 3rd pharyngeal arch endoderm An endoderm that is part of a pharyngeal arch 3. UBERON:0005664 2nd arch endoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005664 2nd pharyngeal arch endoderm An endoderm that is part of a pharyngeal arch 2. CHEBI:19030 1-aminopropan-2-ol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19030 CHEBI:10698 2-cis,6-trans,10-trans-geranylgeranyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_10698 CHEBI:10696 (3S)-3-hydroxy-L-aspartic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_10696 CHEBI:19029 1-aminopropan-2-yl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19029 UBERON:0005659 primary palate epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005659 An epithelium that is part of a primary palate. UBERON:0005658 secondary palatal shelf epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005658 palatal shelf epithelium An epithelium that is part of a secondary palatal shelf. UBERON:0005656 lens vesicle epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005656 An epithelium that is part of a lens vesicle. UBERON:0005638 anterior chamber epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005638 An epithelium that is part of a anterior chamber of eyeball. CHEBI:2003 5,6-dihydroxyindole-2-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_2003 OBO:GOCHE_35473 substance with tranquilizing drug role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_35473 OBO:GOCHE_35471 substance with psychotropic drug role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_35471 OBO:GOCHE_35470 substance with central nervous system drug role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_35470 GO:0043575 detection of osmotic stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043575 The series of events in which a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell is received and converted into a molecular signal. GO:0043574 peroxisomal transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043574 Transport of substances into, out of or within a peroxisome, a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules. OBO:GOCHE_35476 substance with antipsychotic agent role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_35476 GO:0043577 chemotropism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043577 Wikipedia:Chemotropism The movement of an organism, or part of an organism, in response to an external chemical gradient, usually toward or away from it. GO:0043576 regulation of respiratory gaseous exchange biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043576 Any process that modulates the frequency, rate or extent of the process of gaseous exchange between an organism and its environment. GO:0043571 maintenance of CRISPR repeat elements biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043571 maintenance of clustered regularly interspaced short palindromic repeat elements|CRISPR element metabolic process|CRISPR element metabolism Any process involved in sustaining CRISPR repeat clusters, including capture of new spacer elements, expansion or contraction of clusters, propagation of the leader sequence and repeat clusters within a genome, transfer of repeat clusters and CRISPR-associated (cas) genes to new genomes, transcription of the CRISPR repeat arrays into RNA and processing, and interaction of CRISPR/cas loci with the host genome. CRISPR (clustered regularly interspaced short palindromic repeat) elements are a family of sequence elements containing multiple direct repeats of 24-48 bp with weak dyad symmetry which are separated by regularly sized nonrepetitive spacer sequences. GO:0043570 maintenance of DNA repeat elements biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043570 Any process involved in sustaining the fidelity and copy number of DNA repeat elements. GO:0043573 leucoplast fission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043573 The creation of two or more leucoplasts by division of one leucoplast. A leucoplast is a colorless plastid involved in the synthesis of monoterpenes. GO:0043572 plastid fission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043572 The creation of two or more plastids by division of one plastid. A plastid is any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. GO:0043579 elaioplast organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043579 elaioplast organization and biogenesis|elaioplast organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an elaioplast, a leucoplast in which oil is stored. GO:0043578 nuclear matrix organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043578 nuclear matrix organization and biogenesis|nuclear matrix organisation|nucleoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear matrix, the dense fibrillar network lying on the inner side of the nuclear membrane. GO:0043580 periplasmic space organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043580 periplasmic space organization and biogenesis|periplasmic space organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the periplasmic space, the region between the inner (cytoplasmic) and outer membrane in Gram-negative bacteria, or the inner membrane and cell wall in fungi. GO:0043586 tongue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043586 glossa development|lingua development The process whose specific outcome is the progression of the tongue over time, from its formation to the mature structure. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in many other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech. OBO:GOCHE_35488 substance with central nervous system depressant role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_35488 GO:0043585 nose morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043585 nasus morphogenesis The process in which the anatomical structures of the nose are generated and organized. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity). GO:0043588 skin development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043588 animal skin development The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue. GO:0102400 dTDP-3-amino-4-oxo-2,3,6-trideoxy-alpha-D-glucose N,N-dimethyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102400 MetaCyc:RXN-13667 Catalysis of the reaction: 2 S-adenosyl-L-methionine + dTDP-3-amino-4-dehydro-2,3,6-trideoxy-alpha-D-glucose <=> 2 S-adenosyl-L-homocysteine + dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose + 2 H+. GO:0043587 tongue morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043587 lingua morphogenesis|glossa morphogenesis The process in which the anatomical structures of the tongue are generated and organized. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in man other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech. GO:0043582 sporangium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043582 sporangia development The process whose specific outcome is the progression of the sporangium over time, from its formation to the mature structure. A sporangium is a structure producing and containing spores. GO:0102402 2-phenylethyl 6-O-beta-D-xylopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102402 EC:3.2.1.149|MetaCyc:RXN-13694 Catalysis of the reaction: 2-phenylethyl 6-O-beta-D-xylopyranosyl-beta-D-glucopyranoside + H2O = 2-phenylethanol + 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranose. GO:0043581 obsolete mycelium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043581 OBSOLETE. The process whose specific outcome is the progression of the mycelium over time, from its formation to the mature structure. A mycelium consists of a mass of branching, thread-like hyphae. GO:0043584 nose development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043584 nasus development The process whose specific outcome is the progression of the nose over time, from its formation to the mature structure. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity). GO:0102405 (+)-taxifolin 5'-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102405 MetaCyc:RXN-13718|RHEA:61116 Catalysis of the reaction: (+)-taxifolin(1-) + O2 + NADPH(4-) + H+ <=> (+)-dihydromyricetin + NADP(3-) + H2O. GO:0102404 linalyl 6-O-alpha-L-arabinopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102404 EC:3.2.1.149|MetaCyc:RXN-13701 Catalysis of the reaction: linalyl 6-O-alpha-L-arabinopyranosyl- beta-D-glucopyranoside + H2O <=> vicianose + linalool. GO:0043583 ear development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043583 hearing organ development The process whose specific outcome is the progression of the ear over time, from its formation to the mature structure. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals. GO:0102407 sn-2-glycerol-3-phosphate C22:0-DCA-CoA acyl transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102407 MetaCyc:RXN-13734 Catalysis of the reaction: C22:0-DCA-CoA + sn-glycerol 3-phosphate <=> coenzyme A + 2-C22:0-DCA-LPA. GO:0102406 omega-hydroxypalmitate O-sinapoyl transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102406 MetaCyc:RXN-13728|EC:2.3.1.188|RHEA:26470 Catalysis of the reaction: sinapoyl-CoA + 16-hydroxypalmitate <=> coenzyme A + 16-sinapoyloxypalmitate. GO:0102409 sn-2-glycerol-3-phosphate C16:0-CoA acyl transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102409 MetaCyc:RXN-13736 Catalysis of the reaction: behenoyl-CoA + sn-glycerol 3-phosphate(2-) <=> coenzyme A + 2-docosanoyl-glycerol 3-phosphate. GO:0102408 sn-2-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102408 MetaCyc:RXN-13735 Catalysis of the reaction: hexadecanedioyl-CoA + sn-glycerol 3-phosphate <=> coenzyme A + sn-2-C16:0-DCA-LPA. GO:0043589 skin morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043589 The process in which the anatomical structures of the skin are generated and organized. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue. GO:0043591 endospore external encapsulating structure biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0043591 peptidoglycan-based spore wall|endospore wall|spore wall The structures that lie outside the inner membrane and surround the entire endospore; consists of a peptidoglycan-containing inner layer (the endospore cortex) surrounded by a multilayered proteinaceous coat. An exosporium may be present as an extreme outer layer. GO:0018591 methyl tertiary butyl ether 3-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018591 MTBE 3-monooxygenase activity Catalysis of the reaction: methyl tert-butyl ether + 1/2 O2 = tert-butyl alcohol + formaldehyde. GO:0043590 bacterial nucleoid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043590 The region of a bacterial cell to which the DNA is confined. GO:0018590 methylsilanetriol hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018590 UM-BBD_reactionID:r0640 Catalysis of the reaction: methylsilanetriol + O2 + 2 H+ + 2 e- = H2O + hydroxymethylsilanetriol. GO:0043597 cytoplasmic replication fork biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043597 The Y-shaped region of a cytoplasmic replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes. GO:0102410 quercetin-4',3-O-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102410 MetaCyc:RXN-13765 Catalysis of the reaction: quercetin 4'-O-glucoside + UDP-alpha-D-glucose(2-) <=> quercetin 3,4'-O-diglucoside + UDP(3-). GO:0043596 nuclear replication fork biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043596 The Y-shaped region of a nuclear replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes. OBO:GOCHE_35498 substance with diuretic role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_35498 GO:0043599 nuclear DNA replication factor C complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043599 nuclear RFC A nuclear complex of five polypeptides that loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA, thereby permitting processive DNA synthesis catalyzed by DNA polymerase delta or epsilon. In Saccharomyces and several other species, the subunits are known as Rfc1p-Rfc5p, although subunit names do not necessarily correspond between different species. GO:0102412 valerena-4,7(11)-diene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102412 RHEA:34467|EC:4.2.3.139|MetaCyc:RXN-13769 Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> valerena-4,7(11)-diene + diphosphoric acid. GO:0043598 cytoplasmic DNA replication factor C complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043598 cytoplasmic RFC|cytoplasmic clamp loader A cytoplasmic complex of two polypeptides that loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA, thereby permitting processive DNA synthesis catalyzed by DNA polymerase. Examples of this component are found in prokaryotic species. GO:0102411 quercetin-3,4'-O-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102411 MetaCyc:RXN-13766 Catalysis of the reaction: quercetin-3-glucoside + UDP-alpha-D-glucose(2-) <=> quercetin 3,4'-O-diglucoside + UDP(3-). GO:0043593 endospore coat biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043593 The layer in a bacterial endospore that lies under the exosporium, and is impermeable to many toxic molecules. The coat may also contain enzymes that are involved in endospore germination. GO:0102414 quercetin-3-O-glucoside 1,6-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102414 MetaCyc:RXN-13797 Catalysis of the reaction: quercetin-3-glucoside + UDP-alpha-D-glucose(2-) <=> quercetin-3-gentiobioside + UDP. GO:0043592 exosporium biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043592 exospore|epispore|perispore The outermost layer of a bacterial endospore, which is loosely attached and located outside of the endospore coat. It is generally composed of protein, carbohydrate, and perhaps lipid. GO:0102413 6-O-methyl-deacetylisoipecoside beta-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102413 MetaCyc:RXN-13791 Catalysis of the reaction: 6-O-methyl-N-deacetylisoipecoside + H2O <=> 6-O-methyl-N-deacetylisoipecoside aglycon + beta-D-glucose. GO:0043595 endospore cortex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043595 A layer surrounding a bacterial endospore found inside the outer endospore membrane, but outside the membrane surrounding the endospore core. It consists of peptidoglycan of a different chemical nature than that found in vegetative cell walls which results in less cross-linking of peptidoglycan. GO:0102416 quercetin gentiotrioside 1,6-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102416 MetaCyc:RXN-13799 Catalysis of the reaction: quercetin-3-gentiotrioside + UDP-alpha-D-glucose <=> quercetin-3-gentiotetraside + UDP + H+. GO:0043594 outer endospore membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043594 The outer membrane around a bacterial endospore, located between the endospore cortex and endospore coat. GO:0102415 quercetin gentiobioside 1,6-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102415 MetaCyc:RXN-13798 Catalysis of the reaction: quercetin-3-gentiobioside + UDP-alpha-D-glucose <=> quercetin-3-gentiotrioside + UDP + H+. GO:0102418 luteolin-7-O-glucoside 1,6-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102418 MetaCyc:RXN-13801 Catalysis of the reaction: luteolin 7-O-beta-D-glucoside + UDP-alpha-D-glucose = luteolin-7-O-gentiobioside + UDP + H+. GO:0102417 apigenin-7-O-glucoside 1,6-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102417 MetaCyc:RXN-13800 Catalysis of the reaction: apigenin 7-O-beta-D-glucoside + UDP-alpha-D-glucose <=> apigenin-7-O-gentiobioside + UDP + H+. GO:0102419 sn-2-glycerol-3-phosphate omega-OH-C22:0-CoA acyl transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102419 RHEA:33559|MetaCyc:RXN-13803|EC:2.3.1.198 Catalysis of the reaction: omega-hydroxy-C22:0-CoA + sn-glycerol 3-phosphate = coenzyme A + 2-omega-hydroxy-C22:0-LPA. GO:0018589 di-n-butyltin dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018589 UM-BBD_reactionID:r0645 DBT dioxygenase activity Catalysis of the reaction: dibutyltin + O2 + 2 H+ + 2 e- = H2O + beta-hydroxybutylbutyltin. GO:0018586 mono-butyltin dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018586 UM-BBD_reactionID:r0647 MBT dioxygenase activity Catalysis of the reaction: butyltin + O2 + 2 H+ + 2 e- = H2O + beta-hydroxybutyltin. GO:0018585 fluorene oxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018585 UM-BBD_reactionID:r0407 Catalysis of the reaction: fluorene + 2 H+ + 2 e- + O2 = H2O + 9-fluorenol. GO:0018588 tri-n-butyltin dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018588 UM-BBD_reactionID:r0643 TBT dioxygenase activity Catalysis of the reaction: tri-n-butyltin + O2 + 2 H+ + 2 e- = H2O + beta-hydroxybutyldibutyltin. GO:0018587 obsolete limonene 8-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018587 limonene 8-monooxygenase activity OBSOLETE. (Was not defined before being made obsolete). GO:0018582 1-hydroxy-2-naphthoate 1,2-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018582 MetaCyc:1.13.11.38-RXN|RHEA:14749|UM-BBD_reactionID:r0486|EC:1.13.11.38 1-hydroxy-2-naphthoate:oxygen 1,2-oxidoreductase (decyclizing)|1-hydroxy-2-naphthoate dioxygenase activity|1-hydroxy-2-naphthoic acid dioxygenase activity|1-hydroxy-2-naphthoate-degrading enzyme activity Catalysis of the reaction: 1-hydroxy-2-naphthoate + O2 = (3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate. GO:0018581 hydroxyquinol 1,2-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018581 UM-BBD_reactionID:r0232|MetaCyc:HYDROXYQUINOL-12-DIOXYGENASE-RXN|RHEA:19441|EC:1.13.11.37 hydroxyquinol dioxygenase activity|benzene-1,2,4-triol:oxygen 1,2-oxidoreductase (decyclizing) Catalysis of the reaction: benzene-1,2,4-triol + O2 = 3-hydroxy-cis,cis-muconate. GO:0018584 2,4,5-trichlorophenoxyacetic acid oxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018584 EC:1.13.99.-|UM-BBD_reactionID:r0359 Catalysis of the reaction: 2,4,5-trichlorophenoxyacetic acid + 1/2 O2 = glyoxylate + 2,4,5-trichlorophenol. GO:0018583 biphenyl-2,3-diol 1,2-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018583 RHEA:14413|EC:1.13.11.39|MetaCyc:BIPHENYL-23-DIOL-12-DIOXYGENASE-RXN|UM-BBD_enzymeID:e0127 biphenyl-2,3-diol dioxygenase activity|biphenyl-2,3-diol:oxygen 1,2-oxidoreductase (decyclizing)|2,3-dihydroxybiphenyl 1,2-dioxygenase activity|2,3-dihydroxybiphenyl dioxygenase activity Catalysis of the reaction: biphenyl-2,3-diol + O2 = 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H2O. GO:0102421 curcumin-4'-O-beta-D-gentiobioside 1,6-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102421 MetaCyc:RXN-13813 Catalysis of the reaction: curcumin 4'-O-beta-D-gentiobioside + UDP-alpha-D-glucose <=> curcumin 4'-O-beta-D-gentiotrioside + UDP + H+. GO:0102420 sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102420 MetaCyc:RXN-13805|EC:2.3.1.15 Catalysis of the reaction: hexadecanedioyl-CoA + sn-glycerol 3-phosphate = coenzyme A + 1-C16:0-alpha,omega-dicarboxyl-2-lysophosphatidate. GO:0102423 (+)-sesaminol 2-O-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102423 MetaCyc:RXN-13818 Catalysis of the reaction: (+)-sesaminol + UDP-alpha-D-glucose <=> (+)-sesaminol 2-O-beta-D-glucoside + UDP + H+. GO:0102422 curcumin-4'-O-beta-D-gentiotrioside 1,6-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102422 MetaCyc:RXN-13814 Catalysis of the reaction: curcumin 4'-O-beta-D-gentiotrioside + UDP-alpha-D-glucose <=> curcumin 4'-O-beta-D-gentiotetraside + UDP + H+. GO:0102425 myricetin 3-O-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102425 EC:2.4.1.91|MetaCyc:RXN-13822 Catalysis of the reaction: myricetin + UDP-alpha-D-glucose <=> myricetin 3-O-beta-D-glucopyranoside + UDP. GO:0102424 sesaminol-2-O-gentiobioside 1,6-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102424 MetaCyc:RXN-13821 Catalysis of the reaction: (+)-sesaminol 2-O-beta-D-gentiobioside + UDP-alpha-D-glucose <=> (+)-sesaminol 2-O-beta-D-gentiotrioside + UDP + H+. GO:0102427 allocryptopine 6-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102427 MetaCyc:RXN-13828 Catalysis of the reaction: allocryptopine + NADPH + O2 + H+ <=> 6-hydroxy-allocryptopine + NADP + H2O. GO:0102426 myricetin-3-O-glucoside 1,6-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102426 MetaCyc:RXN-13823 Catalysis of the reaction: myricetin 3-O-beta-D-glucopyranoside + UDP-alpha-D-glucose <=> myricetin 3-O-gentiobioside + UDP + H+. GO:0102429 genistein-3-O-glucoside 1,6-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102429 MetaCyc:RXN-13831 Catalysis of the reaction: genistin + UDP-alpha-D-glucose <=> genistin 7-gentiobioside + UDP + H+. GO:0102428 kaempferol-3-O-glucoside 1,6-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102428 MetaCyc:RXN-13830 Catalysis of the reaction: kaempferol 3-O-glucoside + UDP-alpha-D-glucose <=> kaempferol-3-gentiobioside + UDP. GO:0018597 ammonia monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018597 EC:1.14.99.39|UM-BBD_enzymeID:e0061|RHEA:27341 Catalysis of the oxidation of alkanes (up to C8) to alcohols and alkenes (up to C5) to epoxides and alcohols in the presence of ammonium ions. GO:0018596 dimethylsilanediol hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018596 UM-BBD_reactionID:r0637 DMSD hydroxylase activity Catalysis of the reaction: dimethylsilanediol + O2 + 2 H+ + 2 e- = H2O + hydroxymethylmethylsilanediol. GO:0018599 2-hydroxyisobutyrate 3-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018599 UM-BBD_reactionID:r0619 Catalysis of the reaction: 2-hydroxyisobutyrate + 1/2 O2 = 2,3-dihydroxy-2-methyl propionate. GO:0018598 hydroxymethylsilanetriol oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018598 UM-BBD_reactionID:r0641 Catalysis of the reaction: hydroxymethylsilanetriol + O2 + 2 H+ + 2 e- = 2 H2O + formylsilanetriol. GO:0018593 4-chlorophenoxyacetate monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018593 UM-BBD_reactionID:r0281 Catalysis of the reaction: 4-chlorophenoxyacetate + 1/2 O2 = glyoxylate + 4-chlorophenol. GO:0018592 4-nitrocatechol 4-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018592 EC:1.14.13.166|UM-BBD_reactionID:r0231 Catalysis of the reaction: 4-nitrocatechol + O2 + 4 e- + 3 H+ = H2O + nitrite + 1,2,4-benzenetriol. GO:0018595 alpha-pinene monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018595 UM-BBD_reactionID:r0716|EC:1.14.13.155|RHEA:32891 Catalysis of the reaction: alpha-pinene + O2 + 2 H+ + 2 e- = H2O + pinocarveol. GO:0018594 tert-butanol 2-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018594 tert-butyl alcohol 2-monooxygenase activity Catalysis of the reaction: tert-butanol + 1/2 O2 = 2-methyl-2-hydroxy-1-propanol. GO:0018568 3,4-dihydroxyphenanthrene dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018568 UM-BBD_reactionID:r0501|EC:1.13.11.- Catalysis of the reaction: 3,4-dihydroxyphenanthrene + O2 = H+ + 2-hydroxy-2 H-benzo[h]chromene-2-carboxylate. GO:0018567 styrene dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018567 EC:1.13.11.-|UM-BBD_reactionID:r0256 Catalysis of the reaction: styrene + O2 + NADH + H+ = NAD+ + styrene cis-glycol. GO:0018569 hydroquinone 1,2-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018569 UM-BBD_reactionID:r0228|EC:1.13.11.- Catalysis of the reaction: hydroquinone + O2 = cis,trans-4-hydroxymuconic semialdehyde. GO:0018564 carbazole 1,9a-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018564 EC:1.13.11.-|UM-BBD_reactionID:r0456 carbazole 1,9alpha-dioxygenase activity Catalysis of the reaction: carbazole + NADH + O2 + H+ = NAD+ + 2'-aminobiphenyl-2,3-diol. GO:0018563 2,3-dihydroxy-ethylbenzene 1,2-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018563 EC:1.13.11.-|UM-BBD_reactionID:r0310 Catalysis of the reaction: 2,3-dihydroxyethylbenzene + O2 = H+ + 2-hydroxy-6-oxoocta-2,4-dienoate. GO:0018566 1,2-dihydroxynaphthalene-6-sulfonate 1,8a-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018566 EC:1.13.11.-|UM-BBD_reactionID:r0324 1,2-dihydroxynaphthalene-6-sulphonate 1,8a-dioxygenase activity Catalysis of the reaction: 1,2-dihydroxynaphthalene-6-sulfonate + O2 = H+ + (Z)-4-(2-hydroxy-5-sulfonatophenyl)-2-oxo-3-butenoate. GO:0018565 dihydroxydibenzothiophene dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018565 EC:1.13.11.-|UM-BBD_reactionID:r0162 Catalysis of the reaction: 1,2-dihydroxydibenzothiophene + O2 = cis-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate. GO:0018560 protocatechuate 3,4-dioxygenase type II activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018560 EC:1.13.11.-|UM-BBD_reactionID:r0581 Catalysis of the reaction: 4-sulfocatechol + O2 = 3-sulfomuconate. GO:0018562 3,4-dihydroxyfluorene 4,4-alpha-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018562 UM-BBD_reactionID:r0415|EC:1.13.11.- Catalysis of the reaction: 3,4-dihydroxyfluorene + O2 = 2-hydroxy-4-(1-oxo-1,3-dihydro-2H-inden-2-ylidene) but-2-enoic acid. GO:0018561 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018561 EC:1.13.11.-|UM-BBD_reactionID:r0457 Catalysis of the reaction: 2'-aminobiphenyl-2,3-diol + O2 = H+ + 2-hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoate. GO:0018580 nitronate monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018580 MetaCyc:2-NITROPROPANE-DIOXYGENASE-RXN|RHEA:28770|EC:1.13.12.16 2-nitropropane dioxygenase activity|nitronate:oxygen 2-oxidoreductase (nitrite-forming) activity Catalysis of the reaction: ethylnitronate + O(2) = acetaldehyde + nitrite. GO:0018579 protocatechuate 4,5-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018579 RHEA:24044|MetaCyc:PROTOCATECHUATE-45-DIOXYGENASE-RXN|EC:1.13.11.8|UM-BBD_reactionID:r0144 protocatechuate 4,5-oxygenase activity|protocatechuate:oxygen 4,5-oxidoreductase (decyclizing)|protocatechuic 4,5-dioxygenase activity|protocatechuic 4,5-oxygenase activity Catalysis of the reaction: protocatechuate + O2 = 4-carboxy-2-hydroxymuconate semialdehyde. GO:0018578 protocatechuate 3,4-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018578 RHEA:10084|MetaCyc:PROTOCATECHUATE-34-DIOXYGENASE-RXN|EC:1.13.11.3|UM-BBD_reactionID:r0143 protocatechuate:oxygen 3,4-oxidoreductase (decyclizing)|protocatechuic 3,4-dioxygenase activity|protocatechuate oxygenase activity|protocatechuic 3,4-oxygenase activity|protocatechuic acid oxidase activity Catalysis of the reaction: 3,4-dihydroxybenzoate + O2 = 3-carboxy-cis,cis-muconate. GO:0018575 chlorocatechol 1,2-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018575 UM-BBD_reactionID:r0655|EC:1.13.11.- Catalysis of the reaction: 3,6-dichlorocatechol + O2 = 2 H+ + 2,5-dichloro-cis,cis-muconate. GO:0018574 2,6-dichloro-p-hydroquinone 1,2-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018574 UM-BBD_enzymeID:e0422|EC:1.13.11.- Catalysis of the reaction: 2,6-dichlorohydroquinone + O2 + H2O = HCl + 2 H+ + 2-chloromaleylacetate. GO:0018577 catechol 2,3-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018577 UM-BBD_enzymeID:e0156|EC:1.13.11.2|RHEA:17337|MetaCyc:CATECHOL-23-DIOXYGENASE-RXN pyrocatechol 2,3-dioxygenase|catechol 2,3-oxygenase|2,3-pyrocatechase activity|catechol oxygenase|catechol:oxygen 2,3-oxidoreductase (decyclizing)|metapyrocatechase activity|cato2ase activity Catalysis of the reaction: catechol + O2 = 2-hydroxymuconate semialdehyde. GO:0018576 catechol 1,2-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018576 EC:1.13.11.1|UM-BBD_enzymeID:e0064|RHEA:23852|MetaCyc:CATECHOL-12-DIOXYGENASE-RXN catechol:oxygen 1,2-oxidoreductase activity|1,2-pyrocatechase activity|CD I|catechol-oxygen 1,2-oxidoreductase activity|catechol 1,2-oxygenase activity|pyrocatechol 1,2-dioxygenase activity|CD II|pyrocatechase activity|catechase activity Catalysis of the reaction: catechol + O2 = cis,cis-muconate. GO:0018571 2,3-dihydroxy-p-cumate dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018571 MetaCyc:RXN-666|EC:1.13.11.-|RHEA:42568|UM-BBD_reactionID:r0397 2,3-dihydroxy-p-cumate-3,4-dioxygenase|2,3-dihydroxy-p-cumate 3,4-dioxygenase Catalysis of the reaction: 2,3-dihydroxy-p-cumate + O2 = 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate. GO:0018570 p-cumate 2,3-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018570 MetaCyc:RXN-664|EC:1.13.11.-|RHEA:42344|UM-BBD_reactionID:r0395 Catalysis of the reaction: p-cumate + NADH + H+ + O2 = NAD+ + cis-2,3-dihydroxy-2,3-dihydro-p-cumate. GO:0018573 2-aminophenol 1,6-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018573 UM-BBD_reactionID:r0305|EC:1.13.11.- Catalysis of the reaction: 2-aminophenol + O2 = 2-aminomuconic semialdehyde. GO:0018572 3,5-dichlorocatechol 1,2-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018572 EC:1.13.11.-|UM-BBD_reactionID:r0276 Catalysis of the reaction: 3,5-dichlorocatechol + O2 = 2 H+ + 2,4-dichloro-cis,cis-muconate. GO:0018549 methanethiol oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018549 UM-BBD_reactionID:r0209|MetaCyc:METHANETHIOL-OXIDASE-RXN|RHEA:11812|EC:1.8.3.4 methyl mercaptan oxidase activity|methylmercaptan oxidase activity|methanethiol:oxygen oxidoreductase activity|(MM)-oxidase activity|MT-oxidase activity Catalysis of the reaction: methanethiol + O2 + H2O = formaldehyde + hydrogen sulfide + hydrogen peroxide. CHEBI:138888 (R)-3-hydroxy-4-oxobutanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138888 GO:0018546 nitrobenzene nitroreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018546 MetaCyc:RXN-8815|UM-BBD_enzymeID:e0245|RHEA:52884 Catalysis of the reaction: nitrobenzene + 2 NADPH + 2 H+ = hydroxyaminobenzene + 2 NADP+ + H2O. GO:0018545 NAD(P)H nitroreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018545 UM-BBD_enzymeID:e0346 Catalysis of the conversion of a nitrate group to an amino or hydroxylamino group on toluene or a toluene derivative. GO:0018548 pentaerythritol trinitrate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018548 EC:1.6.99.1|UM-BBD_reactionID:r0025 xenobiotic reductase activity Catalysis of the reaction: pentaerythritol trinitrate + NADPH = NADP+ + nitrate + pentaerythritol dinitrate. GO:0018547 nitroglycerin reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018547 UM-BBD_enzymeID:e0038 NG reductase activity Catalysis of the removal of one or more nitrite (NO2-) groups from nitroglycerin or a derivative. GO:0018542 2,3-dihydroxy DDT 1,2-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018542 EC:1.13.11.-|UM-BBD_reactionID:r0452 Catalysis of the reaction: 2,3-dihydroxy DDT + O2 = 6-oxo-2-hydroxy-7-(4-chlorophenyl)-3,8,8,8-tetrachloroocta-2E,4E-dienoate. CHEBI:138881 beta-D-fructofuranose 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138881 GO:0018541 p-benzoquinone reductase (NADPH) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018541 MetaCyc:1.6.5.6-RXN|EC:1.6.5.6|RHEA:23488|KEGG_REACTION:R05244|UM-BBD_enzymeID:e0422 NADPH:p-benzoquinone oxidoreductase activity Catalysis of the reaction: 1,4-benzoquinone + H(+) + NADPH = hydroquinone + NADP(+). GO:0018544 4-carboxy-4'-sulfoazobenzene reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018544 UM-BBD_reactionID:r0543 4-carboxy-4'-sulphoazobenzene reductase activity Catalysis of the reaction: 4-carboxy-4'-sulfoazobenzene + 4 H+ + 4 e- = 4-aminobenzoate + 4-aminobenzenesulfonate. GO:0018543 4-amino-2-nitroso-6-nitrotoluene reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018543 UM-BBD_reactionID:r0464 Catalysis of the reaction: 4-amino-2-hydroxylamino-6-nitrotoluene + NADP+ = NADPH + H+ + 4-amino-2-nitroso-6-nitrotoluene. GO:0018540 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018540 OBO:GOCHE_35469 substance with antidepressant role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_35469 CHEBI:138897 3',5'-unsubstituted flavanone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138897 GO:0018557 1,2-dihydroxyfluorene 1,1-alpha-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018557 EC:1.13.11.-|UM-BBD_reactionID:r0422 Catalysis of the reaction: 1,2-dihydroxyfluorene + O2 = 2-hydroxy-4-(2-oxo-1,3-dihydro-2H-inden-1-ylidene) but-2-enoic acid. GO:0018556 2,2',3-trihydroxybiphenyl dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018556 UM-BBD_enzymeID:e0032|EC:1.13.11.- Catalysis of the reaction: 2,3-dihydroxybenzenoid + O2 = H+ + distal extradiol ring cleavage. Substrates are 2,2',3-trihydroxybiphenyl (forms 2-hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate) and 2,2',3-trihydroxydiphenylether (forms 2,3-hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate). GO:0018559 1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethene 1,2-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018559 EC:1.13.11.-|UM-BBD_reactionID:r0442 1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethylene 1,2-dioxygenase activity Catalysis of the reaction: 1,1-dichloro-2-(dihydroxy-4'-chorophenyl)-2-(4-chlorophenyl)ethene + O2 = 6-oxo-2-hydroxy-7-(4-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7-trienoate. GO:0018558 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018558 EC:1.13.11.-|UM-BBD_reactionID:r0049 Catalysis of the reaction: 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + O2 = 3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon. GO:0018553 3-(2,3-dihydroxyphenyl)propionate 1,2-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018553 UM-BBD_enzymeID:e0309 Catalysis of the reaction: 3-(2,3-dihydroxyphenyl)propionate + O2 = 2-hydroxy-6-keto-nona-2,4-dienedioate. GO:0018552 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018552 GO:0018555 phenanthrene dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018555 EC:1.13.11.-|UM-BBD_reactionID:r0455 Catalysis of the reaction: phenanthrene + NADH + H+ + O2 = NAD+ + cis-3,4-dihydroxy-3,4-dihydrophenanthrene. CHEBI:138890 peregrinol diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138890 GO:0018554 1,2-dihydroxynaphthalene dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018554 RHEA:27310|EC:1.13.11.56|UM-BBD_enzymeID:e0255 Catalysis of the reaction: 1,2-dihydroxynaphthalene + O2 = 2-hydroxychromene-2-carboxylate. C6 of the substrate molecular may have an NH2 group attached. GO:0018551 hydrogensulfite reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018551 MetaCyc:HYDROGENSULFITE-REDUCTASE-RXN|UM-BBD_reactionID:r0627|EC:1.8.99.3|RHEA:13209 desulfoviridin activity|desulforubidin activity|desulfofuscidin activity|dissimilatory sulfite reductase activity|dissimilatory-type sulfite reductase activity|trithionate:(acceptor) oxidoreductase activity|hydrogensulphite reductase activity|bisulfite reductase activity|trithionate:acceptor oxidoreductase activity Catalysis of the reaction: trithionate + acceptor + 2 H2O + OH- = 3 HSO3- + reduced acceptor. GO:0018550 tetrachloro-p-hydroquinone reductive dehalogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018550 UM-BBD_reactionID:r0314|EC:1.8.99.- tetrachlorohydroquinone reductive dehalogenase activity Catalysis of the reaction: 2,3,5,6-tetrachlorohydroquinone + 2 glutathione = 2,3,6-trichlorohydroquinone + glutathione disulfide + HCl. CHEBI:138893 Man-1-2-Ins-1-P-Cer(d18:0)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138893 GO:0102470 6C-naringenin dibenzoylmethane tautomer glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102470 MetaCyc:RXN-14075 Catalysis of the reaction: 2,4,4',6-tetrahydroxydibenzoylmethane + UDP-alpha-D-glucose <=> 6C-glucosyl-2-hydroxynaringenin + UDP + H+. GO:0102472 eriodictyol 2-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102472 RHEA:57596|MetaCyc:RXN-14077 Catalysis of the reaction: eriodictyol + NADPH + O2 + 2 H+ <=> 2-hydroxyeriodictyol + NADP + H2O. GO:0102471 2-hydroxynaringenin-6C-glucoside dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102471 MetaCyc:RXN-14076 Catalysis of the reaction: 6C-glucosyl-2-hydroxynaringenin <=> isovitexin-7-olate + H2O. GO:0102474 eriodictyol dibenzoylmethane tautomer 6C-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102474 MetaCyc:RXN-14080 Catalysis of the reaction: eriodictyol dibenzoylmethane tautomer + UDP-alpha-D-glucose <=> 6C-beta-D-glucosyl-2-hydroxyeriodictyol + UDP + H+. GO:0102473 eriodictyol dibenzoylmethane tautomer 8C-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102473 MetaCyc:RXN-14079 Catalysis of the reaction: eriodictyol dibenzoylmethane tautomer + UDP-alpha-D-glucose <=> 8C-beta-D-glucosyl-2-hydroxyeriodictyol + UDP(3-) + H+. GO:0102476 pinocembrin 2-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102476 RHEA:57592|MetaCyc:RXN-14083 Catalysis of the reaction: pinocembrin + NADPH + O2 + H+ <=> 2,5,7-trihydroxyflavanone + NADP + H2O. GO:0102475 2-hydroxyeriodictyol 6C-glucoside dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102475 MetaCyc:RXN-14081 Catalysis of the reaction: 6C-beta-D-glucosyl-2-hydroxyeriodictyol <=> isoorientin + H2O. GO:0102478 beta-L-arabinofuranosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102478 RHEA:36051|EC:3.2.1.185|MetaCyc:RXN-14089 Catalysis of the reaction: beta-L-arabinofuranosyl-(1->2)-beta-L-arabinofuranose + H2O = 2 beta-L-arabinofuranose. GO:0102477 2,5,7-trihydroxyflavanone 6C-glucoside dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102477 MetaCyc:RXN-14088 Catalysis of the reaction: 6C-glucosyl-2,5,7-trihydroxyflavanone <=> H+ + 6C-hexosyl chrysin + H2O. GO:0102479 quercetin 3-O-beta:-D-galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102479 EC:2.4.1.234|MetaCyc:RXN-14109 Catalysis of the reaction: quercetin-7-olate + UDP-D-galactose <=> quercetin 3-O-beta-D-galactopyranoside + UDP(3-) + H+. CHEBI:44813 N,N-dimethyl-L-prolinium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_44813 CHEBI:78141 1-heptadecylglycerone 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78141 CHEBI:44811 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_44811 CHEBI:78147 fatty alcohol 18:1 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78147 CHEBI:78146 trans-9-octadecenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78146 CHEBI:20847 ADP-glycero-D-manno-heptose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20847 GO:0102481 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102481 RHEA:25836|EC:3.7.1.22|MetaCyc:RXN-14149 Catalysis of the reaction: 3D-3,5/4-trihydroxycyclohexane-1,2-dione + H2O <=> 5-deoxy-D-glucuronate + H+. GO:0102480 5-fluorocytosine deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102480 EC:3.5.4.1|MetaCyc:RXN-14129 Catalysis of the reaction: H+ + flucytosine + H2O <=> 5-fluorouracil + ammonium. GO:0102483 scopolin beta-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102483 MetaCyc:RXN-14179|EC:3.2.1.21 Catalysis of the reaction: H2O + scopolin <=> beta-D-glucose + scopoletin. GO:0102482 5-deoxy-D-glucuronate isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102482 MetaCyc:RXN-14150|EC:5.3.1.30|RHEA:25840 Catalysis of the reaction: 5-deoxy-D-glucuronate = 5-dehydro-2-deoxy-D-gluconate. GO:0102485 dATP phosphohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102485 MetaCyc:RXN-14195|EC:3.6.1.5 Catalysis of the reaction: dATP + 2 H2O = dAMP + 2 hydrogenphosphate + 2 H+. GO:0102484 esculetin glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102484 MetaCyc:RXN-14182 Catalysis of the reaction: esculetin + UDP-alpha-D-glucose(2-) <=> esculin + UDP(3-) + H+. GO:0102487 dUTP phosphohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102487 MetaCyc:RXN-14199|EC:3.6.1.5 Catalysis of the reaction: dUTP + 2 H2O = dUMP + 2 hydrogenphosphate + 2 H+. GO:0102486 dCTP phosphohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102486 MetaCyc:RXN-14198|EC:3.6.1.5 Catalysis of the reaction: dCTP + 2 H2O = dCMP + 2 hydrogenphosphate + 2 H+. GO:0102489 GTP phosphohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102489 MetaCyc:RXN-14201|EC:3.6.1.5 Catalysis of the reaction: GTP + 2 H2O = GMP + 2 hydrogenphosphate + 2 H+. GO:0043500 muscle adaptation biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0043500 muscle plasticity A process in which muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities. GO:0102488 dTTP phosphohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102488 MetaCyc:RXN-14200|EC:3.6.1.5 Catalysis of the reaction: dTTP + 2 H2O = dTMP + 2 hydrogenphosphate + 2 H+. GO:0043506 regulation of JUN kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043506 regulation of JUNK activity Any process that modulates the frequency, rate or extent of JUN kinase activity. CHEBI:78150 fatty alcohol 18:2 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78150 GO:0043505 CENP-A containing nucleosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043505 centromere specific nucleosome|centromeric nucleosome|CNP-T-W-S-X complex|CENP-S-T-W-X|CenH3 containing nucleosome|centromere-specific nucleosome A form of nucleosome located only at the centromere, in which the histone H3 is replaced by the variant form CENP-A (sometimes known as CenH3). GO:0043508 negative regulation of JUN kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043508 negative regulation of JUNK activity|down-regulation of JNK activity|downregulation of JNK activity|down regulation of JNK activity|inhibition of JNK activity Any process that stops, prevents, or reduces the frequency, rate or extent of JUN kinase activity. GO:0043507 positive regulation of JUN kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043507 up regulation of JNK activity|upregulation of JNK activity|stimulation of JNK activity|up-regulation of JNK activity|positive regulation of JUNK activity Any process that activates or increases the frequency, rate or extent of JUN kinase activity. GO:0043502 regulation of muscle adaptation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043502 regulation of muscle plasticity Any process that modulates the frequency, rate or extent of muscle adaptation. GO:0043501 skeletal muscle adaptation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043501 skeletal muscle plasticity Any process in which skeletal muscles change their phenotypic profiles in response to altered functional demands and a variety of signals. CHEBI:19835 3',5'-cyclic pyrimidine nucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19835 CHEBI:19834 3',5'-cyclic purine nucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19834 GO:0043504 mitochondrial DNA repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043504 The process of restoring mitochondrial DNA after damage. GO:0043503 skeletal muscle fiber adaptation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043503 skeletal muscle fiber plasticity|skeletal muscle fibre plasticity|skeletal myofiber plasticity|skeletal myofibre plasticity Any process in which the skeletal muscle fibers change their phenotypic profiles in response to altered functional demands and a variety of signals. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast. CHEBI:44800 (2R,4S)-2-methyltetrahydrofuran-2,3,3,4-tetrol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_44800 CHEBI:20853 AMP-sugar biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20853 CHEBI:20855 ATP-sugar biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20855 CHEBI:20858 C19-gibberellin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20858 GO:0043509 activin A complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043509 A nonsteroidal regulator, composed of two covalently linked inhibin beta-A subunits (sometimes known as activin beta-A or activin/inhibin beta-A). CHEBI:20857 C-glycosyl compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20857 CHEBI:20859 C20-gibberellin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20859 GO:0102490 8-oxo-dGTP phosphohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102490 MetaCyc:RXN-14205|EC:3.6.1.5 Catalysis of the reaction: 8-oxo-dGTP + 2 H2O <=> 8-oxo-dGMP + 2 hydrogenphosphate + 2 H+. GO:0102491 dGTP phosphohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102491 MetaCyc:RXN-14208|EC:3.6.1.5 Catalysis of the reaction: dGTP + 2 H2O = dGMP + 2 hydrogenphosphate + 2 H+. GO:0102494 GA20 2,3-desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102494 MetaCyc:RXN-14317 Catalysis of the reaction: gibberellin A20 + O2 + a reduced electron acceptor <=> gibberellin A5 + 2 H2O + an oxidized electron acceptor. GO:0102493 wogonin 7-O-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102493 MetaCyc:RXN-14239 Catalysis of the reaction: wogonin + UDP-alpha-D-glucose <=> wogonin 7-O-beta-D-glucoside + UDP + H+. GO:0102496 GA5 2,3 epoxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102496 MetaCyc:RXN-14327 Catalysis of the reaction: gibberellin A5 + O2 + 2-oxoglutarate <=> gibberellin A6 + succinate + carbon dioxide. GO:0102495 GA5 3beta-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102495 MetaCyc:RXN-14318 Catalysis of the reaction: gibberellin A5 + O2 + 2-oxoglutarate <=> gibberellin A3 + succinate + carbon dioxide. PR:000020841 oncostatin-M proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000020841 OSM/ClvPrd An oncostatin-M that has been processed by proteolytic cleavage. GO:0102498 maltose glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102498 MetaCyc:RXN-15910 Catalysis of the reaction: H2O + maltose = 2 glucose. UBERON:0005291 embryonic tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005291 developing tissue|portion of embryonic tissue A portion of tissue that is part of an embryo. GO:0102497 scyllo-inositol dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102497 RHEA:39063|MetaCyc:RXN-14347|EC:1.1.1.371 Catalysis of the reaction: scyllo-inositol + NADP <=> 2,4,6/3,5-pentahydroxycyclohexanone + NADPH + H+. UBERON:0005290 myelencephalon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005290 myelencephalon (medulla oblongata) The posterior part of the developing vertebrate hindbrain or the corresponding part of the adult brain composed of the medulla oblongata and a portion of the fourth ventricle; as well as the glossopharyngeal nerve (CN IX), vagus nerve (CN X), accessory nerve (CN XI), hypoglossal nerve (CN XII), and a portion of the vestibulocochlear nerve (CN VIII).[BTO,WP]. GO:0043511 inhibin complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0043511 Heterodimeric hormone composed of an inhibin alpha subunit complexed with either an inhibin beta-A subunit, to form inhibin A, or an inhibin beta-B subunit, to form inhibin B. GO:0043510 activin B complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043510 A nonsteroidal regulator, composed of two covalently linked inhibin beta-B subunits (sometimes known as activin beta-B or activin/inhibin beta-B). GO:0102499 SHG alpha-glucan phosphorylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102499 EC:2.4.1.1|MetaCyc:RXN-14353|RHEA:41732 Catalysis of the reaction: hydrogenphosphate + a plant soluble heteroglycan = alpha-D-glucose 1-phosphate + a plant soluble heteroglycan. GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043517 stimulation of DNA damage response, signal transduction by p53 class mediator|up-regulation of DNA damage response, signal transduction by p53 class mediator|activation of DNA damage response, signal transduction by p53 class mediator|up regulation of DNA damage response, signal transduction by p53 class mediator|positive regulation of p53 induced by DNA damage response|upregulation of DNA damage response, signal transduction by p53 class mediator Any process that activates, maintains or increases the rate of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage. UBERON:0005298 skin of clitoris biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005298 clitoris skin A zone of skin that is part of a clitoris [Automatically generated definition]. GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043516 regulation of p53 induced by DNA damage response Any process that modulates the frequency, rate or extent of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage. UBERON:0005297 testis sex cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005297 testis cord|testis primary sex cords|primary sex cord|testis primitive sex cord The testis cords are precursors to the rete testis. They play several different roles in the development of the male genitals[WP]. GO:0043519 regulation of myosin II filament organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043519 regulation of myosin II filament assembly or disassembly|regulation of myosin II filament organisation Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of a bipolar filament composed of myosin II molecules. UBERON:0005296 ovary sex cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005296 cortical cord|secondary cord|ovigerous cord|cortical sex cord|ovigerous cords|ovary primitive sex cord structures that develop from sex cords in the female. After further development they become the ovarian follicles. GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043518 down-regulation of DNA damage response, signal transduction by p53 class mediator|downregulation of DNA damage response, signal transduction by p53 class mediator|negative regulation of p53 induced by DNA damage response|down regulation of DNA damage response, signal transduction by p53 class mediator|inhibition of DNA damage response, signal transduction by p53 class mediator Any process that stops, prevents, or reduces the frequency, rate or extent of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage. UBERON:0005295 sex cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005295 gonadal cord|genital cord|gonad cord|primitive sex cord Cordlike masses of epithelial tissue that invaginate from germinal epithelium of the gonad and give rise to seminiferous tubules and rete testes in the male, and primary ovarian follicles and rete ovarii in the female. GO:0043513 inhibin B complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043513 Heterodimeric hormone composed of an inhibin alpha subunit complexed with an inhibin beta-B subunit. CHEBI:78165 1-(9Z,12Z,15Z)-octadecatrienylglycerone 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78165 GO:0043512 inhibin A complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043512 Heterodimeric hormone composed of an inhibin alpha subunit complexed with an inhibin beta-A subunit. UBERON:0005294 gonadal ridge biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005294 gonadal ridge|crista gonadalis|indifferent gonadal ridge|genital cord|genital ridge the elevation of thickened mesothelium and underlying mesenchyme found on the ventromedial border of the embryonic mesonephros in which the primordial germ cells become embedded, establishing it as the primordium of the testis or ovary CHEBI:78164 1-(9Z,12Z)-octadecadienylglycerone 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78164 GO:0043515 kinetochore binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043515 Interacting selectively and non-covalently with a kinetochore, a proteinaceous structure on a condensed chromosome, beside the centromere, to which the spindle fibers are attached. CHEBI:78163 1-octadecylglycerone 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78163 GO:0043514 interleukin-12 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043514 IL12B|IL12A|p35|p40|IL-12 complex A protein complex that is composed of an interleukin-12 alpha (p35, product of the IL12A gene) and an interleukin-12 beta subunit (p40, product of the IL12B gene) and is secreted into the extracellular space. UBERON:0005292 extraembryonic tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005292 extra-embryonic tissue Portion of tissue that is contiguous with the embryo and is comprised of portions of tissue or cells that will not contribute to the embryo. CHEBI:78169 monoalkylglycerophosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78169 CHEBI:78168 1-alkylglycerol 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78168 CHEBI:78167 1-lysophosphatidate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78167 CHEBI:78166 2-lysophosphatidate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78166 GO:0043520 regulation of myosin II filament assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043520 Any process that modulates the frequency, rate or extent of the formation of a bipolar filament composed of myosin II molecules. GO:0043522 leucine zipper domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043522 leucine zipper binding Interacting selectively and non-covalently with a leucine zipper domain, a protein secondary structure exhibiting a periodic repetition of leucine residues at every seventh position over a distance covering eight helical turns. GO:0043521 regulation of myosin II filament disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043521 Any process that modulates the frequency, rate or extent of the disassembly of a bipolar filament composed of myosin II molecules. GO:0043528 tRNA (m2G10) methyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043528 A protein complex required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNA. In S. cerevisiae, this complex consists of at least two subunits, Trm11p and Trm112p. UBERON:0005288 tela choroidea of third ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005288 tela choroidea ventriculi tertii|tela chorioidea third ventricle|tela chorioidea of third ventricle|choroid membrane of third ventricle|tela choroidea ventriculi tertii|tela choroidea third ventricle Tela chorioidea that lines the third ventricle[ZFA]. The part of the choroid plexus in relation to the body of the ventricle forms the vascular fringed margin of a triangular process of pia mater, named the tela chorioidea of the third ventricle, and projects from under cover of the lateral edge of the fornix. Blood is supplied by branches from the superior cerebellar artery[WP]. CHEBI:78172 monoacylglycerol 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78172 UBERON:0005287 tela choroidea of fourth ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005287 tela choroidea|tela choroidea of fourth ventricle|tela choroidea ventriculi quarti|choroid membrane|tela choroidea ventriculi quarti|tela chorioidea fourth ventricle|tela choroidea fourth ventricle|choroid membrane of fourth ventricle Tela chorioidea that lines the fourth ventricle[ZFA]. The tela chorioidea of the fourth ventricle is the name applied to the triangular fold of pia mater which is carried upward between the cerebellum and the medulla oblongata. It consists of two layers, which are continuous with each other in front, and are more or less adherent throughout: The posterior layer covers the antero-inferior surface of the cerebellum. The anterior layer is applied to the structures which form the lower part of the roof of the ventricle, and is continuous inferiorly with the pia mater on the inferior peduncles and closed part of the medulla[WP]. GO:0043527 tRNA methyltransferase complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0043527 A multimeric protein complex involved in the methylation of specific nucleotides in tRNA. CHEBI:78171 monoalkenylglycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78171 CHEBI:78170 1-acylglycerophosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78170 GO:0043529 GET complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043529 An endoplasmic reticulum protein-containing complex that is conserved in eukaryotics and that mediates the insertion of tail-anchored proteins into the ER membrane. In yeast, includes Get1p, Get2p and Get3p proteins. GO:0043524 negative regulation of neuron apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043524 down-regulation of neuron apoptosis|negative regulation of programmed cell death, neurons|downregulation of neuron apoptosis|down regulation of neuron apoptosis|inhibition of neuron apoptosis|neuron survival|negative regulation of neuron apoptosis Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons. CHEBI:78176 undecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78176 GO:0043523 regulation of neuron apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043523 regulation of neuronal cell programmed cell death|regulation of neuron apoptosis|regulation of apoptosis of neurons|regulation of apoptosis of neuronal cells|regulation of neuron programmed cell death|regulation of programmed cell death of neuronal cells|regulation of programmed cell death, neurons Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons. CHEBI:78175 1-arachidonoylglycerone 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78175 UBERON:0005283 tela choroidea biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005283 tela chorioidea A structure found in the walls of the ventricles of the brain, consisting of part of the meninges (pia mater in mammals) plus ependyma[cjm]. GO:0043526 obsolete neuroprotection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043526 Wikipedia:Neuroprotection neuroprotection OBSOLETE. Any process that modulates the occurrence or rate of cell death by apoptosis in the nervous system. It may stop or prevent or reduce the rate of cell death by apoptosis and it is activated by stress to counteract death signals in central nervous systems. Different neuroprotective mechanisms may be activated to combat distinct types of cellular stress, ERK pathway is one of several neuroprotective mechanisms and it is a model system to study neuronal apoptosis, which may contribute to several neurodegenerative diseases and aging-related neuron loss. CHEBI:78174 1-(alk-1-enyl)-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78174 UBERON:0005282 ventricular system of brain biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005282 brain ventricular system UBERON:0005281 ventricular system of central nervous system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005281 ventricular system|ventricular system of neuraxis|CNS ventricular system|ventriculi cerebri|ventricle system A set of structures containing cerebrospinal fluid in the brain. It is continuous with the central canal of the spinal cord[WP]. GO:0043525 positive regulation of neuron apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043525 up regulation of neuron apoptosis|positive regulation of programmed cell death, neurons|upregulation of neuron apoptosis|stimulation of neuron apoptosis|activation of neuron apoptosis|up-regulation of neuron apoptosis|positive regulation of neuron apoptosis Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process. CHEBI:78173 1-linoleoylglycerone 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78173 CHEBI:78179 trans-2-heptadecenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78179 CHEBI:78178 (2E,9Z)-hexadecadienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78178 CHEBI:78177 trans-2-undecenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78177 UBERON:0005289 tela choroidea of telencephalic ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005289 tela choroidea of lateral ventricle|tela choroidea telencephalic ventricle|tela chorioidea telencephalic ventricle|tela chorioidea of telencephalic ventricle|tela choroidea (ventriculi lateralis)|tela chorioidea of lateral ventricle Tela chorioidea that lines the telencephalic ventricle. GO:0102430 alpha-linolenate Delta5 desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102430 RHEA:38039|MetaCyc:RXN-13857 Catalysis of the reaction: alpha-linolenate + O2 + a reduced electron acceptor = coniferonate + 2 H2O + an oxidized electron acceptor. GO:0043531 ADP binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043531 adenosine diphosphate binding|adenosine 5'-diphosphate binding Interacting selectively and non-covalently with ADP, adenosine 5'-diphosphate. GO:0102432 quercetin 7-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102432 MetaCyc:RXN-13906 Catalysis of the reaction: quercetin-7-olate + S-adenosyl-L-methionine <=> rhamnetin + S-adenosyl-L-homocysteine. GO:0102431 linoleate Delta5 desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102431 RHEA:46236|MetaCyc:RXN-13858 Catalysis of the reaction: linoleate + O2 + a reduced electron acceptor = pinolenate + 2 H2O + an oxidized electron acceptor. GO:0043530 adenosine 5'-monophosphoramidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043530 adenosine 5' monophosphoramidase activity|adenosine 5'-monophosphoramidate hydrolase activity Catalysis of the reaction: adenosine 5'-monophosphoramidate = AMP + NH2. Other substrates include AMP-morpholidate, AMP-N-alanine methyl ester and AMP-alpha-acetyl lysine methyl ester. GO:0102434 pterin-4alpha-carbinolamine dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102434 MetaCyc:RXN-13908 Catalysis of the reaction: a 10-formyltetrahydrofolate-4a-carbinolamine = H2O + a 10-formyldihydrofolate. GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043533 InsP4 binding|IP4 binding Interacting selectively and non-covalently with inositol 1,3,4,5 tetrakisphosphate. GO:0043532 angiostatin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043532 Interacting selectively and non-covalently with angiostatin, a proteolytic product of plasminogen or plasmin containing at least one intact kringle domain, and which is an inhibitor of angiogenesis. GO:0102433 phenylalanine 4-hydroxylase (N10-formyl-tetrahydrofolate dependent) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102433 MetaCyc:RXN-13907 Catalysis of the reaction: L-phenylalanine + O2 + an N10-formyl-tetrahydrofolate <=> L-tyrosine + a 10-formyltetrahydrofolate-4a-carbinolamine. GO:0102436 7-methylmyricetin 4'-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102436 MetaCyc:RXN-13911 Catalysis of the reaction: 7-O-methylmyricetin + S-adenosyl-L-methionine <=> 7,4'-dimethylmyricetin + S-adenosyl-L-homocysteine + H+. CHEBI:78190 (2E,9Z,12Z)-octadecatrienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78190 GO:0102435 myricetin 7-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102435 MetaCyc:RXN-13910 Catalysis of the reaction: myricetin(1-) + S-adenosyl-L-methionine <=> 7-O-methylmyricetin + S-adenosyl-L-homocysteine. GO:0102438 laricitrin 4'-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102438 MetaCyc:RXN-13914 Catalysis of the reaction: laricitrin(1-) + S-adenosyl-L-methionine <=> H+ + 3',4'-dimethylmyricetin + S-adenosyl-L-homocysteine. GO:0102437 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0102437 CHEBI:78183 1-alkenyl-2-acyl-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78183 GO:0043539 protein serine/threonine kinase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043539 protein ser/thr kinase activator activity Binds to and increases the activity of a protein serine/threonine kinase. CHEBI:78182 1-alkyl-2-acyl-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78182 GO:0043538 regulation of actin phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043538 Any process that modulates the frequency, rate or extent of the transfer of one or more phosphate groups to an actin molecule. GO:0102439 3',4',5'-trimethylmyricetin 7-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102439 MetaCyc:RXN-13916 Catalysis of the reaction: 3',4',5'-trimethylmyricetin + S-adenosyl-L-methionine <=> 7,3',4',5'-tetramethylmyricetin + S-adenosyl-L-homocysteine + H+. CHEBI:78181 (2E,9E)-octadecadienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78181 GO:0043535 regulation of blood vessel endothelial cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043535 Any process that modulates the frequency, rate or extent of the migration of the endothelial cells of blood vessels. CHEBI:78187 (2E,9Z)-octadecadienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78187 GO:0043534 blood vessel endothelial cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043534 The orderly movement of an endothelial cell into the extracellular matrix in order to form new blood vessels during angiogenesis. CHEBI:78186 1-alkyl-2-acyl-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78186 CHEBI:78185 glycero-3-monophosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78185 GO:0043537 negative regulation of blood vessel endothelial cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043537 down-regulation of blood vessel endothelial cell migration|inhibition of blood vessel endothelial cell migration|down regulation of blood vessel endothelial cell migration|downregulation of blood vessel endothelial cell migration Any process that stops, prevents, or reduces the frequency, rate or extent of the migration of the endothelial cells of blood vessels. GO:0043536 positive regulation of blood vessel endothelial cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043536 stimulation of blood vessel endothelial cell migration|up-regulation of blood vessel endothelial cell migration|upregulation of blood vessel endothelial cell migration|up regulation of blood vessel endothelial cell migration|activation of blood vessel endothelial cell migration Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels. CHEBI:78184 monoalkylmonoacylglycerolphosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78184 CHEBI:78189 alkylacylglycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78189 CHEBI:78188 1-(alk-1-enyl)-2-acyl-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78188 CHEBI:20805 (+)-8'-hydroxyabscisic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20805 GO:0102441 syringetin 7-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102441 MetaCyc:RXN-13919 Catalysis of the reaction: syringetin(1-) + S-adenosyl-L-methionine <=> 7,3',5'-trimethylmyricetin + S-adenosyl-L-homocysteine. GO:0102440 3',4',5'-trimethylmyricetin 3-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102440 MetaCyc:RXN-13918 Catalysis of the reaction: 3',4',5'-trimethylmyricetin + S-adenosyl-L-methionine <=> 3,3',4',5'-tetramethylmyricetin + S-adenosyl-L-homocysteine + H+. GO:0102443 L-2-hydroxycarboxylate dehydrogenase (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102443 RHEA:34555|MetaCyc:RXN-13927|EC:1.1.1.337 Catalysis of the reaction: NAD(1-) + a (2S)-2-hydroxycarboxylate <=> NADH(2-) + H+ + a 2-oxo carboxylate. GO:0043542 endothelial cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043542 The orderly movement of an endothelial cell into the extracellular matrix to form an endothelium. GO:0102442 syringetin 3-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102442 MetaCyc:RXN-13920 Catalysis of the reaction: syringetin(1-) + S-adenosyl-L-methionine <=> 3,3',5'-trimethylmyricetin + S-adenosyl-L-homocysteine. GO:0043541 UDP-N-acetylglucosamine transferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043541 A multienzyme, heterooligomeric complex involved in dolichyl-linked oligosaccharide synthesis. In yeast the complex is composed of Alg7p, which catalyzes the first step (GlcNAc1-PP-Dol from dolichol-phosphate and UDP-GlcNAc), and Alg13p plus Alg14p, the catalytic and anchoring subunits respectively, which together catalyze the second step (GlcNAc2-PP-dolichol from GlcNAc1-PP-Dol and UDP-GlcNAc) of dolichyl-linked oligosaccharide synthesis. GO:0102445 3-methylquercetin 3'-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102445 MetaCyc:RXN-13930 Catalysis of the reaction: 3',4',5-trihydroxy-3-methoxyflavon-7-olate + S-adenosyl-L-methionine <=> 3,3'-dimethylquercetin + S-adenosyl-L-homocysteine. GO:0043544 lipoamide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043544 Interacting selectively and non-covalently with lipoamide, the functional form of lipoic acid in which the carboxyl group is attached to protein by an amide linkage to a lysine amino group. GO:0043543 protein acylation biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0043543 protein amino acid acylation The addition of an acyl group, any group or radical of the form RCO- where R is an organic group, to a protein amino acid. GO:0102444 isorhamnetin 3-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102444 MetaCyc:RXN-13929 Catalysis of the reaction: isorhamnetin + S-adenosyl-L-methionine <=> 3,3'-dimethylquercetin + S-adenosyl-L-homocysteine. GO:0102447 rhamnetin 3'-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102447 MetaCyc:RXN-13933 Catalysis of the reaction: rhamnetin + S-adenosyl-L-methionine <=> 7,3'-dimethylquercetin + S-adenosyl-L-homocysteine + H+. GO:0102446 rhamnetin 3-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102446 MetaCyc:RXN-13932 Catalysis of the reaction: rhamnetin + S-adenosyl-L-methionine <=> 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-homocysteine + H+. GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 complex|6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 complex|6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 complex|6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 complex A homodimeric, bifunctional enzyme complex which catalyzes the synthesis and degradation of fructose 2,6-bisphosphate, and is required for both glycolysis and gluconeogenesis. GO:0102449 kaempferol 3-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102449 MetaCyc:RXN-13935 Catalysis of the reaction: kaempferol oxoanion + S-adenosyl-L-methionine <=> 3-O-methylkaempferol + S-adenosyl-L-homocysteine. GO:0102448 rhamnetin 4'-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102448 MetaCyc:RXN-13934 Catalysis of the reaction: rhamnetin + S-adenosyl-L-methionine <=> ombuin + S-adenosyl-L-homocysteine + H+. CHEBI:78194 (2E,4Z,7Z,10Z,13Z,16Z,19Z)-docosaheptaenoyl-coenzyme A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78194 GO:0043549 regulation of kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043549 Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. CHEBI:78193 1-alkylglycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78193 CHEBI:78192 1-lysophosphatidylcholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78192 CHEBI:78191 2-lysophosphatidylcholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78191 CHEBI:78198 1-(alk-1-enyl)-2-acyl-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78198 GO:0043546 molybdopterin cofactor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043546 Moco binding Interacting selectively and non-covalently with the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands. GO:0043545 molybdopterin cofactor metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043545 Moco metabolism|Moco metabolic process|molybdopterin cofactor metabolism The chemical reactions and pathways involving the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands. CHEBI:78197 1-alkyl-2-acyl-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78197 CHEBI:78196 monoalkylglycerophosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78196 GO:0043548 phosphatidylinositol 3-kinase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043548 PI3K binding|phosphoinositide 3-kinase binding Interacting selectively and non-covalently with a phosphatidylinositol 3-kinase, any enzyme that catalyzes the addition of a phosphate group to an inositol lipid at the 3' position of the inositol ring. GO:0043547 positive regulation of GTPase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043547 up regulation of ARF GTPase activity|stimulation of Ran GTPase activity|up regulation of Rac GTPase activity|up-regulation of Rap GTPase activity|up regulation of Rab GTPase activity|up-regulation of Cdc42 GTPase activity|positive regulation of ARF GTPase activity|stimulation of Ral GTPase activity|positive regulation of Rac GTPase activity|up-regulation of Ran GTPase activity|positive regulation of Rab GTPase activity|up-regulation of Ral GTPase activity|stimulation of Rho GTPase activity|up-regulation of GTPase activity|upregulation of Ras GTPase activity|up-regulation of Rho GTPase activity|stimulation of ARF GTPase activity|upregulation of Rap GTPase activity|upregulation of Cdc42 GTPase activity|stimulation of Rac GTPase activity|stimulation of Rab GTPase activity|upregulation of Ran GTPase activity|up-regulation of ARF GTPase activity|upregulation of Ral GTPase activity|up-regulation of Rac GTPase activity|up-regulation of Rab GTPase activity|upregulation of GTPase activity|up regulation of Ras GTPase activity|upregulation of Rho GTPase activity|positive regulation of Ras GTPase activity|up regulation of Rap GTPase activity|up regulation of Cdc42 GTPase activity|up regulation of Ran GTPase activity|upregulation of ARF GTPase activity|positive regulation of Rap GTPase activity|upregulation of Rac GTPase activity|positive regulation of Cdc42 GTPase activity|up regulation of Ral GTPase activity|positive regulation of Ran GTPase activity|upregulation of Rab GTPase activity|positive regulation of Ral GTPase activity|up regulation of GTPase activity|stimulation of Ras GTPase activity|up regulation of Rho GTPase activity|activation of GTPase activity|up-regulation of Ras GTPase activity|stimulation of Rap GTPase activity|positive regulation of Rho GTPase activity|stimulation of GTPase activity|stimulation of Cdc42 GTPase activity Any process that activates or increases the activity of a GTPase. CHEBI:78195 1-(alk-1-enyl)glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78195 CHEBI:78199 alkylacylglycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78199 CHEBI:20814 phenanthrene-9,10-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_20814 GO:0102450 kaempferide 7-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102450 MetaCyc:RXN-13936 Catalysis of the reaction: kaempferide + S-adenosyl-L-methionine <=> 7,4'-dimethylkaempferol + S-adenosyl-L-homocysteine. GO:0102452 bisdemethoxycurcumin synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102452 MetaCyc:RXN-13958|EC:2.3.1.211|RHEA:34803 Catalysis of the reaction: 2 4-coumaryl-CoA + malonyl-CoA + H2O + H+ <=> 3 coenzyme A + bisdemethoxycurcumin + 2 carbon dioxide. PR:000044813 glycoprotein hormone beta chain biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000044813 A protein with a core domain composition consisting of a signal peptide followed by a single copy of the Cys_knot (Pfam:PF00007) domain. The Cysteine knot is a protein structural motif containing three disulfide bridges. GO:0102451 kaempferide 3-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102451 MetaCyc:RXN-13937 Catalysis of the reaction: kaempferide + S-adenosyl-L-methionine <=> 3,4'-dimethylkaempferol + S-adenosyl-L-homocysteine. GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043553 downregulation of phosphatidylinositol 3-kinase activity|negative regulation of phosphoinositide 3-kinase activity|down regulation of phosphatidylinositol 3-kinase activity|inhibition of phosphatidylinositol 3-kinase activity|down-regulation of phosphatidylinositol 3-kinase activity|negative regulation of PI3K activity Any process that stops, prevents, or reduces the frequency, rate or extent of phosphatidylinositol 3-kinase activity. GO:0102454 cyanidin 3-O-galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102454 RHEA:35631|EC:2.4.1.294|MetaCyc:RXN-13960 Catalysis of the reaction: cyanidin + UDP-D-galactose = cyanidin 3-O-beta-D-galactoside betaine + UDP. GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043552 positive regulation of phosphoinositide 3-kinase activity|upregulation of phosphatidylinositol 3-kinase activity|stimulation of phosphatidylinositol 3-kinase activity|activation of phosphatidylinositol 3-kinase activity|up-regulation of phosphatidylinositol 3-kinase activity|up regulation of phosphatidylinositol 3-kinase activity Any process that activates or increases the frequency, rate or extent of phosphatidylinositol 3-kinase activity. GO:0102453 anthocyanidin 3-O-glucoside 6''-O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102453 RHEA:35411|EC:2.3.1.215|MetaCyc:RXN-13959 Catalysis of the reaction: 4-coumaryl-CoA + H+ + an anthocyanidin-3-O-beta-D-glucoside = coenzyme A + H+ + an anthocyanidin-3-O-[6-O-(hydroxycinnamoyl)-beta-D-glucoside]. GO:0043555 regulation of translation in response to stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043555 translational stress response Modulation of the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). GO:0102456 cyanidin 3-O-glucoside 5-O-glucosyltransferase (sinapoyl-glucose dependent) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102456 MetaCyc:RXN-13967 Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-sinapoyl-beta-D-glucose <=> cyanin betaine + trans-sinapate + H+. GO:0043554 aerobic respiration, using arsenite as electron donor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043554 The oxidation of arsenite to arsenate, using oxygen (O2) as the electron acceptor. Arsenite oxidase provides electrons to an electron carrier which transfers them to oxygen utilizing respiratory systems. GO:0102455 anthocyanidin 3-O-glucoside 2''-O-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102455 EC:2.4.1.297|MetaCyc:RXN-13965|RHEA:35419 Catalysis of the reaction: UDP-alpha-D-glucose + an anthocyanidin-3-O-beta-D-glucoside = UDP + H+ + an anthocyanidin 3-O-sophoroside. GO:0102458 cyanidin 3-O-glucoside 5-O glucosyltransferase (vanilloyl-glucose dependent) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102458 EC:2.4.1.299|MetaCyc:RXN-13970 Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-vanilloyl-beta-D-glucose <=> cyanin betaine + vanillate + H+. GO:0102457 cyanidin 3-O-glucoside 7-O-glucosyltransferase (vanilloyl-glucose dependent) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102457 RHEA:35431|EC:2.4.1.300|MetaCyc:RXN-13969 Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-vanilloyl-beta-D-glucose <=> H+ + cyanidin 3,7-di-O-beta-D-glucoside betaine + vanillate. GO:0043551 regulation of phosphatidylinositol 3-kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043551 regulation of phosphoinositide 3-kinase activity Any process that modulates the frequency, rate or extent of phosphatidylinositol 3-kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an inositol lipid at the 3' position of the inositol ring. GO:0043550 regulation of lipid kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043550 Any process that modulates the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid. GO:0102459 8-oxo-deoxyadenine diphosphate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102459 MetaCyc:RXN-14005 Catalysis of the reaction: 8-oxo-dADP + H2O = 8-oxo-dAMP + hydrogenphosphate + H+. GO:0043557 regulation of translation in response to osmotic stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043557 Any process that modulates the frequency, rate or extent of the frequency, rate or extent of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. GO:0043556 regulation of translation in response to oxidative stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043556 Any process that modulates the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. GO:0043559 insulin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043559 Interacting selectively and non-covalently with insulin, a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms. GO:0043558 regulation of translational initiation in response to stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043558 regulation of translation initiation in response to stress Any process that modulates the frequency, rate or extent of translation initiation, as a result of a stimulus indicating the organism is under stress. GO:0102461 kaempferol 3-sophoroside 7-O-rhamnosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102461 MetaCyc:RXN-14009 Catalysis of the reaction: kaempferol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP-L-rhamnose <=> kaempferol 3-O-rhamnosyl(1->2)glucoside-7-O-rhamnoside + UDP. GO:0102460 kaempferol 3-gentiobioside 7-O-rhamnosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102460 MetaCyc:RXN-14008 Catalysis of the reaction: kaempferol-3-gentiobioside + UDP-L-rhamnose = H+ + kaempferol-3-O-gentiobioside-7-O-rhamnoside + UDP. GO:0102463 quercetin 3-gentiobioside 7-O-rhamnosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102463 MetaCyc:RXN-14012 Catalysis of the reaction: quercetin-3-gentiobioside + UDP-L-rhamnose <=> quercetin 3-O-gentiobioside-7-O-rhamnoside + UDP + H+. GO:0102462 quercetin 3-sophoroside 7-O-rhamnosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102462 MetaCyc:RXN-14011 Catalysis of the reaction: quercetin 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP-L-rhamnose <=> quercetin 3-O-rhamnosyl(1->2)glucoside-7-O-rhamnoside + UDP + H+. GO:0102465 zeaxanthin 2,2'-beta-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102465 MetaCyc:RXN-14018 Catalysis of the reaction: zeaxanthin + 2 NADH + 2 H+ + 2 O2 <=> nostoxanthin + 2 NAD + 2 H2O. GO:0043564 Ku70:Ku80 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043564 Ku70:Ku80 heterodimer Heterodimeric protein complex composed of a 70 kDa and a 80 kDa subunit, binds DNA through a channel formed by the heterodimer. Functions in DNA double stranded break repair, chromosome maintenance, transcription regulation, V(D)J recombination, and activation of DNA-PK. GO:0102464 zeaxanthin 2-beta-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102464 MetaCyc:RXN-14016 Catalysis of the reaction: zeaxanthin + O2 + NADH + H+ <=> caloxanthin + H2O + NAD. GO:0043563 obsolete odorant transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043563 OBSOLETE. Enables the directed movement of odorants, any substance capable of stimulating the sense of smell, into, out of or within a cell, or between cells. GO:0102467 scutellarein 7-O-glucuronosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102467 MetaCyc:RXN-14058|RHEA:28318|EC:2.4.1.253 Catalysis of the reaction: UDP-alpha-D-glucuronate + scutellarein <=> UDP( + scutellarin + H+. GO:0043566 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043566 GO:0102466 beta-carotene 2,2'-beta-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102466 MetaCyc:RXN-14019 Catalysis of the reaction: beta-carotene + 2 NADH + 2 H+ + 2 O2 = (2R,2'R)-dihydroxy-all-trans-beta-carotene + 2 NAD + 2 H2O. GO:0043565 sequence-specific DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043565 sequence specific DNA binding Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. GO:0102469 naringenin 2-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102469 MetaCyc:RXN-14069|RHEA:57588 Catalysis of the reaction: (S)-naringenin + NADPH + O2 <=> 2-hydroxynaringenin + NADP + H2O. GO:0043560 insulin receptor substrate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043560 IRS binding|insulin receptor substrate [protein] binding|IRS [protein] binding Interacting selectively and non-covalently with any of the insulin receptor substrate (IRS) proteins, adaptor proteins that bind to the transphosphorylated insulin and insulin-like growth factor receptors, are themselves phosphorylated and in turn recruit SH2 domain-containing signaling molecules to form a productive signaling complex. GO:0102468 wogonin 7-O-glucuronosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102468 EC:2.4.1.253|MetaCyc:RXN-14060|RHEA:28322 Catalysis of the reaction: UDP-alpha-D-glucuronate + wogonin <=> UDP + wogonin 7-O-beta-D-glucuronate + H+. GO:0043562 cellular response to nitrogen levels biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043562 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of inorganic nitrogen. GO:0043561 regulation of translational initiation in response to osmotic stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043561 Any process that modulates the frequency, rate or extent of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043568 positive regulation of IGF receptor signalling pathway|up-regulation of insulin-like growth factor receptor signaling pathway|positive regulation of IGF receptor signaling pathway|upregulation of insulin-like growth factor receptor signaling pathway|positive regulation of insulin-like growth factor receptor signalling pathway|up regulation of insulin-like growth factor receptor signaling pathway|activation of insulin-like growth factor receptor signaling pathway|stimulation of insulin-like growth factor receptor signaling pathway Any process that increases the frequency, rate or extent of insulin-like growth factor receptor signaling. GO:0043567 regulation of insulin-like growth factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043567 regulation of IGF receptor signaling pathway|regulation of insulin-like growth factor receptor signalling pathway|regulation of IGF receptor signalling pathway Any process that modulates the frequency, rate or extent of insulin-like growth factor receptor signaling. GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043569 inhibition of insulin-like growth factor receptor signaling pathway|negative regulation of IGF receptor signalling pathway|negative regulation of IGF receptor signaling pathway|down regulation of insulin-like growth factor receptor signaling pathway|negative regulation of insulin-like growth factor receptor signalling pathway|downregulation of insulin-like growth factor receptor signaling pathway|down-regulation of insulin-like growth factor receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of insulin-like growth factor receptor signaling. CHEBI:29136 pyridine N-oxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29136 CHEBI:138905 phosphatidic acid 36:4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138905 CHEBI:29133 dextrorphan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29133 UBERON:0005352 spermatic cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005352 funiculus spermaticus|spermatic chord The cord-like structure in males comprising the vas deferens and associated tissue that runs from the abdomen down to each testis[MP]. UBERON:0005358 ventricle of nervous system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005358 region of wall of ventricular system of neuraxis|ventricular layer A layer in the central nervous system that lines system of communicating cavities in the brain and spinal cord. UBERON:0005356 Rathke's pouch biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005356 pouch of Rathke|craniopharyngeal pouch|Rathkes pouch epithelium|Rathke pouch|pituitary diverticulum|craniobuccal pouch|nasohypophyseal pouch|adenohypophysial pouch|Rathke's cleft|hypophyseal diverticulum|Rathke's cyst|Rathke's pocket|hypophyseal pouch A pouch of ectoderm that grows out from the upper surface of the embryonic stomodeum and gives rise to the anterior and intermediate lobes of the pituitary gland[MP]. In embryogenesis, Rathke's pouch is a depression in the roof of the developing mouth in front of the buccopharyngeal membrane. It gives rise to the anterior pituitary (adenohypophysis), a part of the endocrine system[WP]. CHEBI:138919 meso-zeaxanthin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138919 UBERON:0005343 cortical plate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005343 future cortical layers II-VI|CxP|neocortex cortical plate|CP|cerebral cortex cortical plate|future neocortex The outer neural tube region in which post-mitotic neuroblasts migrate along radial glia to form the adult cortical layers[MP]. UBERON:0005341 ventral commissure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005341 The fiber tracts that connect the ventral region of the two cerebral hemispheres and span the longitudinal fissure, including the anterior and the habenular commissures[MP]. CHEBI:29152 Cys-tRNA(Cys) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29152 UBERON:0005340 dorsal telencephalic commissure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005340 dorsal commissure A fiber tracts that connect the dorsal region of the two cerebral hemispheres and span the longitudinal fissure, including the corpus callosum and hippocampal commissure[MP]. CHEBI:30109 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30109 CHEBI:29118 methanophenazine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29118 CHEBI:30106 azo group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30106 CHEBI:29119 (2E,4Z)-deca-2,4-dienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29119 CHEBI:30104 diazanetriide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30104 CHEBI:29114 2,5-diamino-4-hydroxy-6-(5-phosphoribosylamino)pyrimidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29114 CHEBI:29110 (+-)-5-[3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydronaphthalen-1(2H)-one biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29110 CHEBI:29112 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29112 CHEBI:29111 alpha-D-GlcpNAc-(1->2)-[alpha-D-Manp-(1->3)]-alpha-D-Manp-(1->2)-alpha-D-Manp-(1->2)-D-Manp biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29111 UBERON:0005332 mesonephric S-shaped body biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005332 The mesonephric S-shaped body is the successor of the mesonephric comma-shaped body that contributes to the morphogenesis of a nephron in the mesonephros[GO]. UBERON:0005331 mesonephric renal vesicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005331 mesonephric vesicle The renal vesicle is the primordial structure of the mesonephric nephron epithelium, and is formed by the condensation of mesenchymal cells[GO]. UBERON:0005330 mesonephric nephron epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005330 The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros[GO]. CHEBI:114953 (2S)-2-ammonio-5-{[iminio(methylamino)methyl]amino}pentanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_114953 CHEBI:30103 diazenide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30103 CHEBI:30102 diazynium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30102 UBERON:0005339 outflow tract pulmonary component biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005339 UBERON:0005338 outflow tract aortic component biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005338 An outflow tract that is part of a aorta. CHEBI:30101 hydrazine-1,1-diide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30101 UBERON:0005337 outflow tract of ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005337 heart ventricle outflow tract|outflow part of ventricle|ventricular outflow tract A ventricular outflow tract is a portion of either the left ventricle or right ventricle of the heart through which blood passes in order to enter the great arteries. The right ventricular outflow tract (RVOT) is an infundibular extension of the ventricular cavity which connects to the pulmonary artery. The left ventricular outflow tract (LVOT), which connects to the aorta, is nearly indistinguishable from the rest of the ventricle[WP]. CHEBI:30100 hydrazine-1,2-diide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30100 UBERON:0005334 oral lamina propria biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005334 lamina propria of oral mucosa A lamina propria that is part of a mucosa of oral region. UBERON:0005333 mammary bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005333 lactiferous gland bud|mammary gland bud|mammary primordium|milk bud A bulb of epithelial cells that forms from the mammary placode that develops into the mammary gland. OBA:VT0000183 blood pressure trait biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_VT0000183 pressure of blood The pressure of a blood. CHEBI:20794 7-methylguanosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_20794 UBERON:0005319 mesonephric collecting duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005319 The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder[GO]. CHEBI:29125 arsenate(3-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29125 CHEBI:29126 trans-dec-3-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29126 CHEBI:29121 oxidonitrate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29121 CHEBI:29123 2-acetamido-5-oxopentanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29123 UBERON:0005321 mesonephric smooth muscle tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005321 . UBERON:0005320 mesonephric juxtaglomerular apparatus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005320 The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate[GO]. CHEBI:44747 homogentisic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_44747 UBERON:0005329 mesonephric nephron tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005329 mesonephric renal tubule A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros[GO]. UBERON:0005328 mesonephric comma-shaped body biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005328 The mesonephric comma-shaped body is the precursor structure to the mesonephric S-shaped body that contributes to the morphogenesis of a nephron in the mesonephros[GO]. UBERON:0005327 mesonephric glomerular epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005327 A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros[GO]. UBERON:0005326 mesonephric glomerulus vasculature biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005326 The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus[GO]. UBERON:0005325 mesonephric glomerulus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005325 glomerulus The mesonephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or mesonephros[GO]. UBERON:0005324 mesonephric macula densa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005324 The mesonephric macula densa is an area of specialized cells in the distal tubule of the mesonephros that makes contact with the vascular pole of the glomerulus[GO]. UBERON:0005323 mesonephric mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005323 Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros[GO]. UBERON:0005322 mesonephric nephron biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005322 stage IV nephron|nephron of mesonephros A nephron that is part of a mesonephros. CHEBI:78109 1-decyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78109 CHEBI:78108 1-decyl-2-acetyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78108 UBERON:0005398 female reproductive gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005398 A sex gland that is part of a female reproductive system. UBERON:0005397 brain arachnoid mater biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005397 arachnoidea mater cranialis|brain arachnoid matter|cranial arachnoid mater|arachnoidea mater encephali An arachnoid mater that surrounds a brain. UBERON:0005396 carotid artery segment biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005396 carotid artery|subdivision of common carotid artery|carotid|common carotid arterial subdivision One of: the common carotid artery, or its branches, the external and internal carotid arteries. CHEBI:78103 1-dodecyl-2-acetyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78103 CHEBI:78102 1-tetradecyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78102 CHEBI:78101 1-tetradecyl-2-acetyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78101 CHEBI:78100 trioxilin A3(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78100 CHEBI:19763 2-phosphoglycolate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19763 CHEBI:78104 1-dodecyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78104 UBERON:0005399 male reproductive gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005399 accessory sex gland A sex gland that is part of a male reproductive system. CHEBI:78119 fatty acid anion 12:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78119 CHEBI:29107 24-methylidenelophenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29107 CHEBI:29109 (+-)-5-[3-(tert-butylamino)-2-hydroxypropoxy]-1,2,3,4-tetrahydro-1-naphthol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29109 CHEBI:29108 calcium(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29108 CHEBI:29103 potassium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29103 CHEBI:29105 zinc(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29105 CHEBI:29101 sodium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29101 UBERON:0005386 olfactory segment of nasal mucosa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005386 pars olfactoria tunicae mucosae nasi|olfactory part of nasal mucosa|pars olfactoria tunicae mucosae nasi|olfactory area of nasal mucosa|olfactory zone of nasal mucosa|olfactory mucosa That portion of the nasal mucosa containing the sensory endings for olfaction; the organ of smell[MESH]. UBERON:0005384 nasal cavity epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005384 nasal epithelium|nasal mucosa An epithelium that lines the nasal cavity. UBERON:0005383 caudate-putamen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005383 caudate putamen|dorsal striatum|caudate putamen|caudoputamen|caudateputamen|striatum|caudateputamen|caudate-putamen|neostriatum|caudate putamen (striatum) Regional part of telencephalon in some species, e.g., rodent, equivalent to the dorsal striatum (caudate nucleus and putamen). Unlike the dorsal striatum of primates, for example, the caudoputamen is not split into separate nuclei by the fibers of the internal capsule. Rather, the internal capsule splits into fiber bundles which course through the structure. UBERON:0005382 dorsal striatum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005382 striatum dorsale|dorsal basal ganglia|striatum dorsal region|caudoputamen|corpus striatum|dorsal basal ganglion|striated body Dorsal components of the striatum comprising the caudate nucleus and the putamen, in species that have distinct nuclei; the caudoputamen in species which don't. UBERON:0005381 dentate gyrus granule cell layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005381 granular layer of the dentate gyrus|DG granule cell layer|stratum granulare gyri dentati|dentate gyrus, granule cell layer|granular layer of dentate gyrus Granule cell layer is also called the DG principal cell layer. This one of the three layers of dentate gyrus that lies deep to the molecular layer and is made of densely packed layer that is four to eight granule cells thick. CHEBI:78114 1-tetradecylglycerone 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78114 CHEBI:78113 fatty acid anion 3:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78113 CHEBI:78112 1-dodecylglycerone 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78112 CHEBI:78111 1-oleylglycerone 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78111 CHEBI:78118 fatty acid anion 10:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78118 CHEBI:78117 fatty acid anion 8:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78117 CHEBI:78116 fatty acid anion 6:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78116 UBERON:0005389 transparent eye structure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005389 lens A transparent structure that is part of a visual sense organ, the function of which is to direct or focus light onto a photoreceptor array. UBERON:0005388 photoreceptor array biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005388 light-sensitive tissue An array of photoreceptors and any supporting cells found in an eye. CHEBI:78115 fatty acid anion 4:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78115 UBERON:0005373 spinal cord dorsal column biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005373 posterior column|dorsal columns|dorsal column system|dorsal column of spinal cord|spinal cord posterior column|dorsal column the wedge-shaped fiber bundle of white matter in the dorsomedial side of the spinal cord that is made up of the fasciculus gracilis and fasciculus cuneatus; it is part of the ascending posterior column-medial lemniscus pathway that is important for well-localized fine touch and conscious proprioception CHEBI:78121 fatty acid anion 14:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78121 CHEBI:78125 fatty acid anion 18:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78125 CHEBI:78124 fatty acid anion 17:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78124 CHEBI:78123 fatty acid anion 16:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78123 CHEBI:78122 fatty acid anion 15:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78122 CHEBI:78129 fatty acid anion 26:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78129 CHEBI:78128 fatty acid anion 24:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78128 CHEBI:78127 fatty acid anion 22:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78127 CHEBI:78126 fatty acid anion 20:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78126 CHEBI:20750 6-phospho-2-dehydro-D-gluconate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_20750 UBERON:0005362 vagus X ganglion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005362 vagus X|ganglion of vagus nerve|vagus neural ganglion|vagal ganglion|gX|right glossopharyngeal ganglion|vagus ganglion the group of sensory neuron cell bodies associated with the vagus nerve CHEBI:78131 fatty acid anion 30:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78131 CHEBI:78130 fatty acid anion 28:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78130 CHEBI:78136 fatty alcohol 16:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78136 CHEBI:78135 1-pentadecylglycerone 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78135 CHEBI:19775 quinaldate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_19775 CHEBI:78133 fatty alcohol 14:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78133 CHEBI:78139 fatty alcohol 20:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78139 UBERON:0005367 hippocampus granule cell layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005367 hippocampus granular layer CHEBI:78138 fatty alcohol 18:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78138 UBERON:0005366 olfactory lobe biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005366 The lobe at the anterior part of each cerebral hemisphere, responsible for olfactory functions. GO:0018528 iminodiacetate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018528 UM-BBD_reactionID:r0589 Catalysis of the reaction: iminodiacetate + OH- = H+ + 2 e- + glyoxylate + glycine. GO:0018527 cyclohexylamine oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018527 UM-BBD_reactionID:r0754|EC:1.4.3.12|RHEA:18433|MetaCyc:CYCLOHEXYLAMINE-OXIDASE-RXN cyclohexylamine:oxygen oxidoreductase (deaminating) Catalysis of the reaction: cyclohexylamine + O2 + H2O = cyclohexanone + NH3 + hydrogen peroxide. GO:0018529 nitrilotriacetate monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018529 EC:1.14.14.10|UM-BBD_reactionID:r0587 Catalysis of the reaction: nitrilotriacetate + NADH + H+ + O2 = NAD+ + H2O + glyoxylate + iminodiacetate. GO:0018524 acetophenone carboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018524 UM-BBD_reactionID:r0033|EC:6.4.1.- Catalysis of the reaction: acetophenone + CO2 = H+ + benzoyl acetate. GO:0018523 quinoline 2-oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018523 RHEA:17749|UM-BBD_reactionID:r0045|MetaCyc:1.3.99.17-RXN|EC:1.3.99.17 quinoline:acceptor 2-oxidoreductase (hydroxylating) Catalysis of the reaction: quinoline + acceptor + H2O = isoquinolin-1(2H)-one + reduced acceptor. GO:0018526 2-aminobenzoyl-CoA reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018526 UM-BBD_reactionID:r0342 Catalysis of the reaction: 2-aminobenzoyl-CoA + 2 H+ + 2 e- = NH3 + benzoyl-CoA. GO:0018525 4-hydroxybenzoyl-CoA reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018525 MetaCyc:OHBENZCOARED-RXN|UM-BBD_reactionID:r0158|EC:1.3.7.9|KEGG_REACTION:R05316|RHEA:29603 4-hydroxybenzoyl-coA reductase (dehydroxylating) activity|4-hydroxybenzoyl-coA:(acceptor) oxidoreductase activity Catalysis of the reaction: benzoyl-CoA + oxidized ferredoxin + H2O = 4-hydroxybenzoyl-CoA + reduced ferredoxin. GO:0018520 cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018520 EC:1.3.1.67|UM-BBD_reactionID:r0179|MetaCyc:1.3.1.67-RXN cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate:NAD(P)+ oxidoreductase (decarboxylating)|4-methylcyclohexa-3,5-diene-1,2-cis-diol-1-carboxylic acid dehydrogenase activity Catalysis of the reaction: cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate + NADP+ = 4-methylcatechol + NADPH + H+ + CO2. CHEBI:138980 AZD1979(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138980 GO:0018522 benzoyl-CoA reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018522 EC:1.3.7.8|RHEA:30199|KEGG_REACTION:R02451|UM-BBD_reactionID:r0190|MetaCyc:1.3.99.15-RXN cyclohexa-1,5-diene-1-carbonyl-CoA:ferredoxin oxidoreductase (aromatizing, ATP-forming) activity|benzoyl-CoA reductase (dearomatizing) activity Catalysis of the reaction: 2 ADP + cyclohexa-1,5-diene-1-carbonyl-CoA + oxidized ferredoxin + 2 phosphate = 2 ATP + 2 H(2)O + benzoyl-CoA + reduced ferredoxin. GO:0018521 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018521 EC:1.3.1.68|UM-BBD_reactionID:r0224|RHEA:15657|KEGG_REACTION:R05314|MetaCyc:1.3.1.68-RXN 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate:NAD+ oxidoreductase (decarboxylating) Catalysis of the reaction: 1,6-dihydroxy-2-methylcyclohexa-2,4-dienecarboxylate + NAD(+) = 3-methylcatechol + CO(2) + NADH. GO:0018538 epoxide carboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018538 Catalysis of the generic reaction: epoxide + CO2 + NAD+ + electron donor = beta-keto acid + NADH + reduced electron donor; the electron donor may be NADPH or a dithiol. This reaction is the ring opening and carboxylation of an epoxide; for example: epoxypropane + CO2 + NAD+ + NADPH = acetoacetate + NADH + NADP+. GO:0018535 nicotine dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018535 MetaCyc:NICOTINE-DEHYDROGENASE-RXN|UM-BBD_enzymeID:e0337|EC:1.5.99.4|RHEA:14769 nicotine:acceptor 6-oxidoreductase (hydroxylating)|nicotine oxidase activity|nicotine:(acceptor) 6-oxidoreductase (hydroxylating)|D-nicotine oxidase activity Catalysis of the reaction: nicotine + acceptor + H2O = (S)-6-hydroxynicotine + reduced acceptor. GO:0018534 nitrilotriacetate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018534 UM-BBD_reactionID:r0588|EC:1.5.99.- Catalysis of the reaction: nitrilotriacetate + OH- = H+ + 2 e- + glyoxylate + iminodiacetate. GO:0018537 coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018537 RHEA:21144|KEGG_REACTION:R04464|EC:1.5.98.2|MetaCyc:METHELENE-THMPT-OXI-RXN|UM-BBD_reactionID:r0354 5,10-methylenetetrahydromethanopterin cyclohydrolase activity|5,10-methylenetetrahydromethanopterin reductase activity|methylenetetrahydromethanopterin reductase activity|5-methyltetrahydromethanopterin:coenzyme-F420 oxidoreductase activity|N(5),N(10)-methylenetetrahydromethanopterin reductase activity|N5,N10-methylenetetrahydromethanopterin:coenzyme-F420 oxidoreductase activity|methylene-H(4)MPT reductase activity|methylene-H4MPT reductase activity|N5,N10-methylenetetrahydromethanopterin reductase activity|N(5),N(10)-methylenetetrahydromethanopterin:coenzyme-F420 oxidoreductase activity|coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin reductase activity Catalysis of the reaction: 5-methyltetrahydromethanopterin + coenzyme F420 + H(+) = 5,10-methylenetetrahydromethanopterin + reduced coenzyme F420. GO:0018536 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018536 GO:0018531 (S)-6-hydroxynicotine oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018531 RHEA:11880|EC:1.5.3.5|MetaCyc:S-6-HYDROXYNICOTINE-OXIDASE-RXN|UM-BBD_reactionID:r0478|KEGG_REACTION:R03202 (S)-6-hydroxynicotine:oxygen oxidoreductase activity|6-hydroxy-L-nicotine oxidase activity|L-6-hydroxynicotine oxidase activity|6-hydroxy-L-nicotine:oxygen oxidoreductase activity Catalysis of the reaction: (S)-6-hydroxynicotine + H(2)O + O(2) = 6-hydroxypseudooxynicotine + H(2)O(2). GO:0018530 (R)-6-hydroxynicotine oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018530 RHEA:10012|EC:1.5.3.6|KEGG_REACTION:R07170|MetaCyc:R-6-HYDROXYNICOTINE-OXIDASE-RXN|UM-BBD_reactionID:r0477 D-6-hydroxynicotine oxidase activity|(R)-6-hydroxynicotine:oxygen oxidoreductase activity|6-hydroxy-D-nicotine oxidase activity Catalysis of the reaction: (R)-6-hydroxynicotine + H(2)O + O(2) = 6-hydroxypseudooxynicotine + H(2)O(2). GO:0018533 peptidyl-cysteine acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018533 The acetylation of peptidyl-cysteine. GO:0018532 5,10-methenyl-5,6,7,8-tetrahydromethanopterin dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018532 EC:1.5.99.-|UM-BBD_reactionID:r0353 coenzyme F420-independent 5,10-methenyl-5,6,7,8-tetrahydromethanopterin dehydrogenase activity|coenzyme F420-independent methylene-H4MPT dehydrogenase activity|F420-independent 5,10-methenyl-5,6,7,8-tetrahydromethanopterin dehydrogenase activity|F420-independent methylene-H4MPT dehydrogenase activity Catalysis of the reaction: N5,N10-methenyltetrahydromethanopterin + H2 = N5,N10-methylenetetrahydromethanopterin. CHEBI:29198 phosphinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29198 GO:0018509 cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018509 MetaCyc:1.3.1.56-RXN|RHEA:17033|UM-BBD_enzymeID:e0134|EC:1.3.1.56 2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase activity|biphenyl-2,3-dihydro-2,3-diol dehydrogenase activity|cis-3-phenylcyclohexa-3,5-diene-1,2-diol:NAD+ oxidoreductase activity Catalysis of the reaction: cis-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+ = biphenyl-2,3-diol + NADH + H+. GO:0018506 maleylacetate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018506 MetaCyc:MALEYLACETATE-REDUCTASE-RXN|UM-BBD_enzymeID:e0063|EC:1.3.1.32 3-oxoadipate:NAD(P)+ oxidoreductase activity|maleolylacetate reductase activity Catalysis of the reaction: 3-oxoadipate + NAD(P)+ = 2-maleylacetate + NAD(P)H + H+. CHEBI:138966 9beta-pimara-7,15-diene-3beta-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138966 GO:0018505 cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018505 EC:1.3.1.29|UM-BBD_enzymeID:e0122|RHEA:11832|MetaCyc:1.3.1.29-RXN (+)-cis-naphthalene dihydrodiol dehydrogenase activity|cis-dihydrodiol naphthalene dehydrogenase activity|cis-naphthalene dihydrodiol dehydrogenase activity|naphthalene dihydrodiol dehydrogenase activity|1,2-dihydroxy-1,2-dihydroxynaphthalene dehydrogenase activity|cis-1,2-dihydronaphthalene-1,2-diol:NAD+ 1,2-oxidoreductase activity Catalysis of the reaction: cis-1,2-dihydronaphthalene-1,2-diol + NAD+ = naphthalene-1,2-diol + NADH + H+. CHEBI:138965 11,20-dihydroxyferruginol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138965 GO:0018508 cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018508 UM-BBD_enzymeID:e0219 benzoate cis-diol dehydrogenase activity Catalysis of the reaction: cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate + NAD+ = catechol + CO2 + NADH + H+. CHEBI:138964 2-hydroxyisovaleryl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138964 GO:0018507 cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018507 KEGG_REACTION:R04151|RHEA:16253|EC:1.3.1.49|UM-BBD_reactionID:r0488|MetaCyc:1.3.1.49-RXN (+)-cis-3,4-dihydrophenanthrene-3,4-diol:NAD+ 3,4-oxidoreductase activity|cis-3,4-dihydroxy-3,4-dihydrophenanthrene dehydrogenase activity Catalysis of the reaction: (3S,4R)-3,4-dihydrophenanthrene-3,4-diol + NAD(+) = H(+) + NADH + phenanthrene-3,4-diol. CHEBI:138963 11,20-dihydroxysugiol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138963 GO:0018502 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018502 MetaCyc:LINC-RXN|UM-BBD_reactionID:r0553|RHEA:15741 Catalysis of the reaction: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol + NAD+ = NADH + H+ + 2,5-dichlorohydroquinone. GO:0018501 cis-chlorobenzene dihydrodiol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018501 UM-BBD_enzymeID:e0411 Catalysis of the conversion of a di- or tetrachlorinated dienol to the corresponding catechol. CHEBI:138969 ent-cassa-12,15-dien-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138969 CHEBI:138968 ent-cassa-12,15-dien-2beta,3beta-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138968 GO:0018504 cis-1,2-dihydrobenzene-1,2-diol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018504 EC:1.3.1.19|UM-BBD_enzymeID:e0060|MetaCyc:1.3.1.19-RXN|RHEA:15457 cis-1,2-dihydrobenzene-1,2-diol:NAD+ oxidoreductase activity|cis-benzene glycol dehydrogenase activity|cis-1,2-dihydrocyclohexa-3,5-diene (nicotinamide adenine dinucleotide) oxidoreductase activity Catalysis of the reaction: cis-1,2-dihydrobenzene-1,2-diol + NAD+ = catechol + NADH + H+. GO:0018503 trans-1,2-dihydrodiolphenanthrene dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018503 UM-BBD_reactionID:r0574 Catalysis of the reaction: trans-1,2-dihydrodiolphenanthrene + NAD+ = H+ + NADH + 1,2-dihydroxyphenanthrene. CHEBI:138967 ent-cassa-12,15-dien-2beta-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138967 GO:0018500 trans-9R,10R-dihydrodiolphenanthrene dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018500 UM-BBD_reactionID:r0575 Catalysis of the reaction: trans-9R,10R-dihydrodiolphenanthrene + NAD+ = NADH + H+ + 9,10-dihydroxyphenanthrene. CHEBI:138962 11-hydroxysugiol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138962 CHEBI:138961 sugiol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138961 GO:0018517 phthalate 4,5-cis-dihydrodiol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018517 EC:1.3.1.64|UM-BBD_reactionID:r0142|KEGG_REACTION:R05275|MetaCyc:1.3.1.64-RXN|RHEA:13837 cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate:NAD+ oxidoreductase activity Catalysis of the reaction: cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD(+) = 4,5-dihydroxyphthalate + H(+) + NADH. CHEBI:138977 quorum sensing inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138977 GO:0018516 2,4-dichlorobenzoyl-CoA reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018516 KEGG_REACTION:R05276|RHEA:23076|MetaCyc:1.3.1.63-RXN|EC:1.21.1.2|UM-BBD_reactionID:r0138 4-chlorobenzoyl-CoA:NADP+ oxidoreductase (halogenating) Catalysis of the reaction: 4-chlorobenzoyl-CoA + chloride + NADP(+) = 2,4-dichlorobenzoyl-CoA + NADPH. GO:0018519 cis-dihydroethylcatechol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018519 EC:1.3.1.66|KEGG_REACTION:R05313|RHEA:18101|MetaCyc:1.3.1.66-RXN|UM-BBD_reactionID:r0309 cis-ethylbenzene glycol dehydrogenase activity|cis-1,2-dihydro-3-ethylcatechol:NAD+ oxidoreductase activity Catalysis of the reaction: cis-1,2-dihydro-3-ethylcatechol + NAD(+) = 3-ethylcatechol + H(+) + NADH. CHEBI:138975 mogroside IE biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138975 GO:0018518 5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018518 EC:1.3.1.65|RHEA:24556|UM-BBD_reactionID:r0053|KEGG_REACTION:R05312|MetaCyc:RXN-643 5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline:NAD+ oxidoreductase activity|5,6-dihydrodiol-3-methyl-2-oxo-1,2-dihydroquinoline dehydrogenase Catalysis of the reaction: 5,6-dihydroxy-3-methyl-5,6-dihydroquinolin-2(1H)-one + NAD(+) = 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + H(+) + NADH. CHEBI:138974 mogrol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138974 GO:0018513 dibenzothiophene dihydrodiol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018513 EC:1.3.1.60|UM-BBD_reactionID:r0161|RHEA:24188|KEGG_REACTION:R05310|MetaCyc:1.3.1.60-RXN cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene:NAD+ oxidoreductase activity Catalysis of the reaction: cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene + NAD(+) = 1,2-dihydroxydibenzothiophene + H(+) + NADH. GO:0018512 obsolete 1,6-dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018512 UM-BBD_reactionID:r0216 1,2-dihydroxy-3-methylcyclohexa-3,5-diene-carboxylate dehydrogenase activity|1,6-dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate dehydrogenase activity OBSOLETE. Catalysis of the reaction: 1,6-dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate + NAD+ = 3-methylcatechol + CO2 + NADH + H+. GO:0018515 pimeloyl-CoA dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018515 EC:1.3.1.62|UM-BBD_reactionID:r0194|KEGG_REACTION:R05311|RHEA:19665|MetaCyc:1.3.1.62-RXN pimeloyl-CoA:NAD+ oxidoreductase activity Catalysis of the reaction: NAD(+) + pimelyl-CoA = 2,3-didehydropimeloyl-CoA + H(+) + NADH. CHEBI:138979 hemisuccinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138979 GO:0018514 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018514 GO:0018511 2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018511 UM-BBD_reactionID:r0396|RHEA:23772|KEGG_REACTION:R05240|MetaCyc:RXN-665|EC:1.3.1.58 cis-2,3-dihydroxy-2,3-dihydro-p-cumate:NAD+ oxidoreductase activity Catalysis of the reaction: cis-2,3-dihydroxy-2,3-dihydro-p-cumate + NAD(+) = 2,3-dihydroxy-p-cumate + H(+) + NADH. GO:0018510 phloroglucinol reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018510 RHEA:10080|EC:1.3.1.57|UM-BBD_reactionID:r0007|KEGG_REACTION:R05308|MetaCyc:R5-RXN dihydrophloroglucinol:NADP+ oxidoreductase activity Catalysis of the reaction: dihydrophloroglucinol + NADP(+) = H(+) + NADPH + phloroglucinol. CHEBI:138973 11-oxocucurbitadienol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138973 CHEBI:138972 11alpha-hydroxycucurbitadienol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138972 CHEBI:138971 drimendiol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138971 CHEBI:138970 ent-3beta-hydroxycassa-12,15-dien-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138970 GOREL:0002008 obsolete has intermediate biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GOREL_0002008 GOREL:0002008 UBERON:0005309 pronephric nephron biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005309 A pronephric nephron is the functional unit of the pronephros[GO]. UBERON:0005308 nephrostome biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005308 The nephrostome is the opening of the pronephros into the body cavity[GO]. GOREL:0002001 obsolete results_in_assembly_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GOREL_0002001 GOREL:0002001 CHEBI:29179 tRNA(Ser) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29179 GOREL:0002003 results_in_distribution_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GOREL_0002003 GOREL:0002003 GOREL:0002002 obsolete results_in_disassembly_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GOREL_0002002 GOREL:0002002 GOREL:0002005 results_in_fusion_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GOREL_0002005 GOREL:0002005 CHEBI:29176 tRNA(Gly) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29176 GOREL:0002004 results_in_fission_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GOREL_0002004 GOREL:0002004 CHEBI:29175 tRNA(Glu) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29175 GOREL:0002007 obsolete results_in_remodeling_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GOREL_0002007 GOREL:0002007 CHEBI:29178 tRNA(His) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29178 GOREL:0002006 obsolete results_in_organization_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GOREL_0002006 GOREL:0002006 CHEBI:29177 tRNA(Pro) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29177 CHEBI:138944 salviol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138944 UBERON:0005310 pronephric nephron tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005310 pronephric tubule|ciliated neck segment The pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron and connects the filtration unit (glomerulus or glomus) of the pronephros to the pronephric duct[GO]. CHEBI:29183 tRNA(Val) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29183 CHEBI:29182 tRNA(Tyr) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29182 CHEBI:138943 carnosate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138943 CHEBI:29185 tRNA(Lys) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29185 CHEBI:138942 11-hydroxyferruginol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138942 CHEBI:29184 tRNA(Phe) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29184 CHEBI:138941 2-hydroxyoctanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138941 CHEBI:138948 (4S)-2,3-dehydroleucocyanidin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138948 CHEBI:29181 tRNA(Trp) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29181 CHEBI:138946 cochalate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138946 CHEBI:138945 maniladiol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138945 CHEBI:29180 tRNA(Thr) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29180 UBERON:0005317 pulmonary artery endothelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005317 pulmonary artery endothelial tube An pulmonary artery endothelium is an epithelium that lines the pulmonary artery[GO]. UBERON:0005316 endocardial endothelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005316 endothelium of endocardium|endocardium endothelium The endothelial lining of the endocardium. CHEBI:30166 boride(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30166 UBERON:0005315 alveolar secondary septum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005315 A secondary alveolar septum is a specialized epithelium that subdivides the initial saccule[GO]. UBERON:0005314 alveolar primary septum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005314 A primary alveolar septum is a specialized epithelium that surrounds the saccule as it forms[GO]. CHEBI:138940 1-O-hexadecyl-2-(8-carboxyoctanoyl)-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138940 UBERON:0005313 mammary duct terminal end bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005313 A unique club-shaped epithelial structure that develops at the tip of the mammary duct at the onset of puberty under the action of circulating hormones. CHEBI:30164 5-diphospho-1D-myo-inositol pentakisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30164 UBERON:0005312 primary ureteric bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005312 . UBERON:0005311 mammary placode biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005311 mammary anlage The mammary placode is a transient lens shaped structure that will give rise to the mammary bud proper[GO]. NCBITaxon:2704647 Metakinetoplastina organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_2704647 CHEBI:29186 tRNA(Asp) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29186 CHEBI:138955 daturadiol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138955 CHEBI:29195 cyanate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29195 CHEBI:138959 2-hydroxydecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138959 CHEBI:29192 hydrogenperoxide(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29192 UBERON:0005307 chorion-containing eggshell biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005307 An eggshell that contains chorion. An example of this is found in Drosophila melanogaster. CHEBI:138951 3'-hydroxy-5'-unsubstituted flavanone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138951 CHEBI:138950 (4S)-2,3-dehydroleucopelargonidin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138950 CHEBI:29158 Asp-tRNA(Asp) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29158 CHEBI:29157 Glu-tRNA(Glu) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29157 CHEBI:138929 N-hexadecanoyl-1,2-diheptadecanoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138929 CHEBI:29159 Trp-tRNA(Trp) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29159 CHEBI:29154 Pro-tRNA(Pro) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29154 CHEBI:29153 Phe-tRNA(Phe) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29153 CHEBI:29156 Gly-tRNA(Gly) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29156 CHEBI:29155 His-tRNA(His) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29155 CHEBI:29161 Tyr-tRNA(Tyr) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29161 CHEBI:138922 1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138922 CHEBI:29160 Ile-tRNA(Ile) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29160 CHEBI:29163 Thr-tRNA(Thr) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29163 CHEBI:29162 Ser-tRNA(Ser) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29162 CHEBI:138926 1,2-diheptadecanoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138926 CHEBI:138923 1-heptanoyl-2-hexanoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138923 CHEBI:44788 2-succinylbenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_44788 CHEBI:29169 tRNA(Leu) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29169 CHEBI:29168 tRNA(Gln) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29168 CHEBI:138938 EC 4.1.1.39 (ribulose-bisphosphate carboxylase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138938 CHEBI:44785 peroxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_44785 CHEBI:29164 Val-tRNA(Val) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29164 CHEBI:29167 tRNA(Cys) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29167 CHEBI:29166 Gln-tRNA(Gln) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29166 CHEBI:29172 tRNA(Asn) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29172 CHEBI:29171 tRNA(Arg) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29171 CHEBI:29174 tRNA(Ile) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29174 CHEBI:29173 tRNA(Met) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29173 CHEBI:138930 N-oleoyl-1,2-diheptadecanoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138930 CHEBI:138937 D-xylulose 1,5-bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138937 CHEBI:138936 N(6)-hexadecanoyl-L-lysine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138936 CHEBI:29170 tRNA(Ala) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29170 CHEBI:138934 N-(4-oxoglutaryl)-L-cysteinylglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138934 CHEBI:30156 6,7-dihydropteridine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30156 CHEBI:30154 5beta-pregnane-3,20-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30154 GO:0043690 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043690 GO:0004088 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004088 Reactome:R-HSA-73577|EC:6.3.5.5|RHEA:18633|MetaCyc:CARBPSYN-RXN glutamine-dependent carbamoyl-phosphate synthase activity|GD-CPSase activity|carbamyl phosphate synthetase (glutamine) activity|glutamine-dependent carbamyl phosphate synthetase activity|carbamoyl-phosphate synthase (glutamine-hydrolysing) activity|hydrogen-carbonate:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) activity|carbamoyl phosphate synthetase activity|CPS activity|carbon-dioxide::L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) activity|carbamoylphosphate synthetase II activity|carbamoyl-phosphate synthetase (glutamine-hydrolysing) activity|carbamoyl-phosphate synthetase (glutamine-hydrolyzing) activity|carbamoyl phosphate synthase (glutamine-hydrolyzing) activity Catalysis of the reaction: 2 ATP + L-glutamine + CO2 + H2O = 2 ADP + phosphate + glutamate + carbamoyl phosphate. GO:0043696 dedifferentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043696 Wikipedia:Cellular_differentiation#Dedifferentiation The process in which a specialized structure (cell, tissue or organ) loses structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these structures can revert back to the features of their ancestors. GO:0004087 carbamoyl-phosphate synthase (ammonia) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004087 RHEA:10624|KEGG_REACTION:R00149|EC:6.3.4.16|MetaCyc:6.3.4.16-RXN|Reactome:R-HSA-70555 carbon-dioxide:ammonia ligase (ADP-forming, carbamate-phosphorylating)|carbamoylphosphate synthase activity|CPS I activity|carbamoyl-phosphate synthetase (ammonia) activity|carbamoyl phosphate synthase (ammonia) activity|carbamoylphosphate synthetase (ammonia) activity|carbmoylphosphate synthetase activity|carbon-dioxide--ammonia ligase activity|carbamylphosphate synthetase I|carbamoylphosphate synthase (ammonia)|carbamylphosphate synthetase activity|carbamoyl-phosphate synthetase I activity Catalysis of the reaction: 2 ATP + CO(2) + H(2)O + NH(4)(+) = 2 ADP + carbamoyl phosphate + 5 H(+) + phosphate. GO:0043695 detection of pheromone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043695 The series of events in which a pheromone stimulus is received by a cell and converted into a molecular signal. GO:0043698 iridosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043698 reflecting platelet A tissue-specific, membrane-bounded cytoplasmic organelle within which purines crystalize in reflective stacks. Iridosomes are synthesized in iridophore cells and are silver, gold or iridescent in appearance. GO:0004089 carbonate dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004089 Reactome:R-HSA-1237045|Reactome:R-HSA-1475028|Reactome:R-HSA-1475032|Reactome:R-HSA-1475017|Reactome:R-HSA-1475025|EC:4.2.1.1|MetaCyc:CARBODEHYDRAT-RXN|Reactome:R-HSA-1475435|Reactome:R-HSA-1237047|Reactome:R-HSA-1475436|Reactome:R-HSA-1237059|Reactome:R-HSA-1475022|RHEA:10748|Reactome:R-HSA-1475026|Reactome:R-HSA-1237081 carbonic dehydratase activity|anhydrase activity|carbonate hydro-lyase (carbon-dioxide-forming)|carbonate anhydrase activity|carbonate hydro-lyase activity|carbonic anhydrase activity|carbonic acid anhydrase activity|carbonic anhydrase A|carboxyanhydrase activity Catalysis of the reaction: H2CO3 = CO2 + H2O. GO:0043697 cell dedifferentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043697 The process in which a specialized cell loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors. GO:0004084 branched-chain-amino-acid transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004084 Reactome:R-HSA-70724|Reactome:R-HSA-70723|EC:2.6.1.42|Reactome:R-HSA-508179|Reactome:R-HSA-508189 branched-chain amino acid aminotransferase activity|branched-chain-amino-acid:2-oxoglutarate aminotransferase activity|L-branched chain amino acid aminotransferase activity|branched-chain aminotransferase activity|glutamate-branched-chain amino acid transaminase activity|branched-chain amino acid-glutamate transaminase activity|transaminase B activity Catalysis of the reaction: a branched-chain amino acid + 2-oxoglutarate = L-glutamate + a 2-oxocarboxylate derived from the branched-chain amino acid. GO:0043692 monoterpene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043692 monoterpene metabolism The chemical reactions and pathways involving monoterpenes, terpenes with a C10 structure. GO:0004083 bisphosphoglycerate 2-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004083 MetaCyc:BISPHOSPHOGLYCERATE-PHOSPHATASE-RXN|RHEA:21904|KEGG_REACTION:R01516 2,3-bisphospho-D-glycerate 2-phosphohydrolase activity Catalysis of the reaction: 2,3-bisphospho-D-glycerate + H(2)O = 3-phospho-D-glycerate + phosphate. GO:0043691 reverse cholesterol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043691 The directed movement of peripheral cell cholesterol, cholest-5-en-3-beta-ol, towards the liver for catabolism. GO:0004086 obsolete carbamoyl-phosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004086 carbamoyl-phosphate synthase activity|carbamoyl phosphate synthase activity OBSOLETE. Catalysis of a reaction that results in the formation of carbamoyl phosphate. GO:0043694 monoterpene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043694 monoterpene catabolism The chemical reactions and pathways resulting in the breakdown of monoterpenes, terpenes with a C10 structure. GO:0004085 butyryl-CoA dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004085 UM-BBD_reactionID:r0013|KEGG_REACTION:R01178|EC:1.3.8.1|MetaCyc:BUTYRYL-COA-DEHYDROGENASE-RXN short-chain acyl-coenzyme A dehydrogenase activity|short-chain-acyl-CoA dehydrogenase activity|short-chain acyl CoA dehydrogenase activity|ethylene reductase activity|unsaturated acyl coenzyme A reductase activity|butyryl coenzyme A dehydrogenase activity|butanoyl-CoA:(acceptor) 2,3-oxidoreductase activity|butanoyl-CoA:acceptor 2,3-oxidoreductase activity|3-hydroxyacyl CoA reductase activity|enoyl-coenzyme A reductase activity|butyryl dehydrogenase activity|unsaturated acyl-CoA reductase activity Catalysis of the reaction: butanoyl-CoA + electron-transfer flavoprotein = 2-butenoyl-CoA + reduced electron-transfer flavoprotein. GO:0043693 monoterpene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043693 monoterpene biosynthesis The chemical reactions and pathways resulting in the formation of monoterpenes, terpenes with a C10 structure. GO:0004091 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004091 GO:0004090 carbonyl reductase (NADPH) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004090 EC:1.1.1.184|MetaCyc:CARBONYL-REDUCTASE-NADPH-RXN|Reactome:R-HSA-8937419|RHEA:19257 aldehyde reductase I activity|secondary-alcohol:NADP+ oxidoreductase activity|xenobiotic ketone reductase activity|prostaglandin 9-ketoreductase activity|carbonyl reductase activity|aldehyde reductase 1|NADPH-dependent carbonyl reductase activity|NADPH2-dependent carbonyl reductase activity|ALR3|nonspecific NADPH-dependent carbonyl reductase activity Catalysis of the reaction: R-CHOH-R' + NADP+ = R-CO-R' + NADPH + H+. GO:0004093 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004093 GO:0004092 carnitine O-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004092 MetaCyc:CARNITINE-O-ACETYLTRANSFERASE-RXN|Reactome:R-HSA-390284|Reactome:R-HSA-390291|RHEA:21136|KEGG_REACTION:R02396|EC:2.3.1.7 acetylcarnitine transferase activity|carnitine acetyltransferase activity|carnitine O-acetyltransferase II activity|acetyl-CoA-carnitine O-acetyltransferase activity|CATC|carnitine-acetyl-CoA transferase activity|carnitine acetylase activity|carnitine O-acetyltransferase I activity|carnitine acetyl coenzyme A transferase activity|acetyl-CoA:carnitine O-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + carnitine = (R)-O-acetylcarnitine + CoA. GO:0043699 leucosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043699 refractosome A tissue-specific, membrane-bounded cytoplasmic organelle within which uric acid and/or purines crystalize in reflective stacks. Leucosomes are synthesized in leucophore cells and have a whitish cast. GO:0004099 chitin deacetylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004099 RHEA:10464|EC:3.5.1.41|MetaCyc:CHITIN-DEACETYLASE-RXN chitin amidohydrolase activity Catalysis of the reaction: chitin + H2O = chitosan + acetate. GO:0004098 cerebroside-sulfatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004098 EC:3.1.6.8|RHEA:21300|Reactome:R-HSA-1606807|MetaCyc:CEREBROSIDE-SULFATASE-RXN cerebroside sulfate sulfatase activity|arylsulfatase A activity|cerebroside-sulphatase activity|cerebroside-3-sulfate 3-sulfohydrolase activity Catalysis of the reaction: a cerebroside 3-sulfate + H2O = a cerebroside + sulfate. PR:000029394 ATP-dependent RNA helicase DDX58 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000029394 retinoic acid-inducible gene 1 protein|RLR-1|DDX58|RIG-I-like receptor 1|retinoic acid-inducible gene I protein|RIG-1|DEAD box protein 58|RIG-I A protein that is a translation product of the human DDX58 gene or a 1:1 ortholog thereof. GO:0004095 carnitine O-palmitoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004095 EC:2.3.1.21|Reactome:R-HSA-200410|RHEA:12661|Reactome:R-HSA-200406|MetaCyc:CARNITINE-O-PALMITOYLTRANSFERASE-RXN CPTi|acylcarnitine transferase activity|CPT-B|carnitine palmitoyltransferase-A|CPT-A|palmitoyl-CoA:L-carnitine O-palmitoyltransferase activity|carnitine palmitoyltransferase II|outer malonyl-CoA inhibitable carnitine palmitoyltransferase activity|carnitine palmitoyltransferase I|palmitoylcarnitine transferase activity|CPT I (outer membrane carnitine palmitoyl transferase)|CPTo|CPT|carnitine palmitoyltransferase activity|L-carnitine palmitoyltransferase activity Catalysis of the reaction: palmitoyl-CoA + L-carnitine = CoA + L-palmitoylcarnitine. GO:0004094 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004094 GO:0004097 catechol oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004097 RHEA:21632|MetaCyc:CATECHOL-OXIDASE-RXN|EC:1.10.3.1 o-diphenol:oxygen oxidoreductase|phenolase activity|tyrosinase activity|o-diphenol oxidoreductase|dopa oxidase|pyrocatechol oxidase|o-diphenolase activity|diphenol oxidase activity|1,2-benzenediol:oxygen oxidoreductase activity|catecholase|polyphenol oxidase activity Catalysis of the reaction: 2 catechol + O2 = 2 1,2-benzoquinone + 2 H2O. GO:0004096 catalase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004096 UM-BBD_enzymeID:e0834|Reactome:R-HSA-76031|RHEA:20309|Reactome:R-HSA-1222704|MetaCyc:CATAL-RXN|EC:1.11.1.6 CAT|manganese catalase activity|heme catalase activity|catalase reaction|optidase activity|equilase activity|bacterial catalase-peroxidase activity|hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|catalase-peroxidase activity|caperase activity|haem catalase activity Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O. GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004069 RHEA:21824|MetaCyc:ASPAMINOTRANS-RXN|Reactome:R-HSA-70596|KEGG_REACTION:R00355|Reactome:R-HSA-70613|Reactome:R-HSA-70592|EC:2.6.1.1|Reactome:R-HSA-70581 L-aspartate-alpha-ketoglutarate transaminase activity|2-oxoglutarate-glutamate aminotransferase activity|oxaloacetate-aspartate aminotransferase activity|glutamate-oxalate transaminase activity|glutamate-oxalacetate aminotransferase activity|glutamic-aspartic aminotransferase activity|aspartate-2-oxoglutarate transaminase activity|aspartate:2-oxoglutarate aminotransferase activity|oxaloacetate transferase activity|L-aspartic aminotransferase activity|glutamic--aspartic transaminase activity|aspartate aminotransferase activity|aspartic aminotransferase activity|aspartic acid aminotransferase activity|aspartate alpha-ketoglutarate transaminase activity|aspartate transaminase activity|L-aspartate-2-oxoglutarate-transaminase activity|L-aspartate transaminase activity|glutamate oxaloacetate transaminase activity|glutamic oxalic transaminase activity|L-aspartate-2-oxoglutarate aminotransferase activity|glutamic-oxalacetic transaminase activity|aspartyl aminotransferase activity|AspT|GOT (enzyme)|transaminase A activity|AAT|L-aspartate-2-ketoglutarate aminotransferase activity|glutamic--oxaloacetic transaminase activity Catalysis of the reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate. GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004066 RHEA:12228|EC:6.3.5.4|MetaCyc:ASNSYNB-RXN|Reactome:R-HSA-70599 AS|asparagine synthetase B activity|glutamine-dependent asparagine synthetase activity|asparagine synthase (glutamine-hydrolysing)|asparagine synthetase (glutamine-hydrolyzing) activity|L-aspartate:L-glutamine amido-ligase (AMP-forming)|AS-B activity|asparagine synthetase (glutamine-hydrolysing) Catalysis of the reaction: ATP + L-aspartate + L-glutamine = AMP + diphosphate + L-asparagine + L-glutamate. GO:0004065 arylsulfatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004065 EC:3.1.6.1|MetaCyc:ARYLSULFAT-RXN|RHEA:17261 aryl-sulphate sulphohydrolase activity|sulfatase activity|phenolsulfatase activity|arylsulfohydrolase activity|arylsulphatase activity|nitrocatechol sulfatase activity|phenylsulfatase activity|p-nitrophenyl sulfatase activity|estrogen sulfatase activity|4-methylumbelliferyl sulfatase activity|aryl-sulfate sulfohydrolase activity|aryl-sulfate sulphohydrolase activity Catalysis of the reaction: a phenol sulfate + H2O = a phenol + sulfate. GO:0004068 aspartate 1-decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004068 EC:4.1.1.11|MetaCyc:PWY-5155|RHEA:19497|MetaCyc:ASPDECARBOX-RXN L-aspartate 1-carboxy-lyase (beta-alanine-forming)|aspartic alpha-decarboxylase|L-aspartate alpha-decarboxylase activity|aspartate alpha-decarboxylase activity|L-aspartate 1-carboxy-lyase activity Catalysis of the reaction: L-aspartate = beta-alanine + CO2. GO:0004067 asparaginase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004067 RHEA:21016|MetaCyc:ASPARAGHYD-RXN|EC:3.5.1.1|Reactome:R-HSA-6797627 L-asparagine amidohydrolase activity|asparaginase II|alpha-asparaginase activity|crasnitin|colaspase activity|elspar|L-asparaginase activity|leunase activity Catalysis of the reaction: L-asparagine + H2O = L-aspartate + NH3. GO:0004062 aryl sulfotransferase activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0004062 Reactome:R-HSA-158468|Reactome:R-HSA-176646|Reactome:R-HSA-176585|Reactome:R-HSA-158860|EC:2.8.2.1|MetaCyc:ARYL-SULFOTRANSFERASE-RXN|RHEA:12164|Reactome:R-HSA-176474|Reactome:R-HSA-159358|Reactome:R-HSA-158849 4-nitrocatechol sulfokinase activity|aryl sulphotransferase activity|dopamine sulfotransferase activity|2-naphtholsulfotransferase activity|1-naphthol phenol sulfotransferase activity|phenol sulfokinase activity|ritodrine sulfotransferase activity|sulfokinase activity|phenol sulfotransferase activity|3'-phosphoadenylyl-sulfate:phenol sulfotransferase activity|arylsulfotransferase|p-nitrophenol sulfotransferase activity|PST Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a phenol = adenosine 3',5'-bisphosphate + an aryl sulfate. GO:0004061 arylformamidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004061 RHEA:13009|MetaCyc:ARYLFORMAMIDASE-RXN|EC:3.5.1.9|Reactome:R-HSA-71189 formylase activity|formamidase I|formylkynureninase activity|kynurenine formamidase activity|formamidase II|formylkynurenine formamidase activity|aryl-formylamine amidohydrolase activity Catalysis of the reaction: N-formyl-L-kynurenine + H2O = formate + L-kynurenine. GO:0004064 arylesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004064 MetaCyc:ARYLESTERASE-RXN|RHEA:17309|EC:3.1.1.2|UM-BBD_reactionID:r0757 paraoxonase activity|A-esterase activity|aromatic esterase|aryl-ester hydrolase Catalysis of the reaction: a phenyl acetate + H2O = a phenol + acetate. GO:0004063 aryldialkylphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004063 MetaCyc:ARYLDIALKYLPHOSPHATASE-RXN|EC:3.1.8.1|RHEA:18053|UM-BBD_enzymeID:e0054 esterase B1|esterase E4|organophosphorus acid anhydrase activity|phosphotriesterase activity|aryltriphosphatase activity|paraoxon hydrolase activity|aryltriphosphate dialkylphosphohydrolase activity|organophosphate hydrolase activity|OPH|paraoxonase activity|organophosphate esterase activity|A-esterase activity|pirimiphos-methyloxon esterase activity|paraoxon esterase activity|organophosphorus hydrolase activity Catalysis of the reaction: aryl dialkyl phosphate + H2O = dialkyl phosphate + an aryl alcohol. GO:0004071 aspartate-ammonia ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004071 MetaCyc:ASNSYNA-RXN|RHEA:11372|EC:6.3.1.1 L-asparagine synthetase activity|asparagine synthetase activity|L-aspartate:ammonia ligase (AMP-forming) Catalysis of the reaction: ATP + L-aspartate + NH3 = AMP + diphosphate + L-asparagine. GO:0004070 aspartate carbamoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004070 Reactome:R-HSA-73573|RHEA:20013|KEGG_REACTION:R01397|MetaCyc:ASPCARBTRANS-RXN|EC:2.1.3.2 aspartic carbamyltransferase activity|L-aspartate transcarbamoylase activity|aspartic transcarbamylase activity|aspartate transcarbamoylase activity|ATCase activity|aspartate carbamyltransferase activity|carbamoylaspartotranskinase activity|carbamylaspartotranskinase activity|aspartic acid transcarbamoylase activity|aspartate transcarbamylase activity|L-aspartate transcarbamylase activity|carbamoyl-phosphate:L-aspartate carbamoyltransferase activity Catalysis of the reaction: L-aspartate + carbamoyl phosphate = N-carbamoyl-L-aspartate + H(+) + phosphate. GO:0004077 biotin-[acetyl-CoA-carboxylase] ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004077 MetaCyc:BIOTINLIG-RXN|RHEA:11756|EC:6.3.4.15 biotin holoenzyme synthetase activity|acetyl CoA holocarboxylase synthetase activity|biotin:apo-acetyl-CoA:carbon-dioxide ligase (ADP-forming) ligase (AMP-forming)|biotin-acetyl coenzyme A carboxylase synthetase activity|biotin:apocarboxylase ligase activity|HCS|biotin--protein ligase activity|acetyl-CoA carboxylase biotin holoenzyme synthetase activity|biotin-acetyl-CoA carboxylase synthetase|acetyl coenzyme A holocarboxylase synthetase activity|biotin-acetyl-CoA-carboxylase ligase activity|biotin--[acetyl-CoA carboxylase] synthetase activity Catalysis of the reaction: ATP + biotin + apo-(acetyl-CoA:carbon-dioxide ligase (ADP forming)) = AMP + diphosphate + (acetyl-CoA:carbon-dioxide ligase (ADP forming)). GO:0102300 linoleate 9R-lipoxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102300 RHEA:31691|MetaCyc:RXN-12760|EC:1.13.11.61 Catalysis of the reaction: linoleate + O2 = 9(R)-HPODE. GO:0004076 biotin synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004076 RHEA:22060|MetaCyc:2.8.1.6-RXN|EC:2.8.1.6|KEGG_REACTION:R01078 dethiobiotin:sulfur sulfurtransferase activity|biotin synthetase activity Catalysis of the reaction: 2 S-adenosyl-L-methionine + dethiobiotin + S(2-) = 2 5'-deoxyadenosine + 2 L-methionine + biotin + H(+). GO:0004079 biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004079 MetaCyc:6.3.4.9-RXN|EC:6.3.4.9|RHEA:23668 biotin:apomethylmalonyl-CoA:pyruvate carboxytransferase ligase (AMP-forming)|biotin-transcarboxylase synthetase activity|biotin-methylmalonyl coenzyme A carboxyltransferase synthetase activity|biotin-methylmalonyl-CoA-carboxytransferase synthetase activity|biotin-methylmalonyl-CoA-carboxytransferase ligase activity|biotin-[methylmalonyl-CoA-carboxyltransferase] ligase activity|biotin:apomethylmalonyl-CoA:pyruvate carboxyltransferase ligase (AMP-forming)|biotin--[methylmalonyl-CoA-carboxytransferase] synthetase activity|biotin-methylmalonyl-CoA-carboxyltransferase synthetase|methylmalonyl coenzyme A holotranscarboxylase synthetase activity|biotin-methylmalonyl-CoA-carboxyltransferase ligase activity|biotin--[methylmalonyl-CoA-carboxyltransferase] synthetase activity|biotin--[methylmalonyl-CoA-carboxyltransferase] ligase activity Catalysis of the reaction: ATP + biotin + apo-(methylmalonyl-CoA:pyruvate carboxytransferase) = AMP + diphosphate + (methylmalonyl-CoA:pyruvate carboxytransferase). GO:0102302 mycinamicin VI 2''-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102302 RHEA:31643|EC:2.1.1.238|MetaCyc:RXN-12801 Catalysis of the reaction: S-adenosyl-L-methionine + mycinamicin VI <=> S-adenosyl-L-homocysteine + mycinamicin III(1+) + H+. GO:0004078 biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004078 MetaCyc:6.3.4.11-RXN|EC:6.3.4.11|RHEA:24376 biotin-methylcrotonoyl-CoA-carboxylase ligase activity|biotin--[methylcrotonoyl-CoA-carboxylase] synthetase activity|biotin:apo-3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming) ligase (AMP-forming)|biotin-beta-methylcrotonyl coenzyme A carboxylase synthetase activity|beta-methylcrotonyl coenzyme A holocarboxylase synthetase activity|biotin-methylcrotonoyl-CoA-carboxylase synthetase Catalysis of the reaction: ATP + biotin + apo-(3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)) = AMP + diphosphate + (3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)). GO:0102301 gamma-linolenate elongase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102301 MetaCyc:RXN-12777 Catalysis of the reaction: malonyl-CoA + gamma-linolenoyl-CoA + H+ = (8Z,11Z,14Z)-3-oxoicosa-8,11,14-trienoyl-CoA + coenzyme A + carbon dioxide. GO:0102304 sesquithujene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102304 RHEA:31991|EC:4.2.3.102|MetaCyc:RXN-12838 Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> 7-epi-sesquithujene + diphosphoric acid. GO:0004073 aspartate-semialdehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004073 MetaCyc:ASPARTATE-SEMIALDEHYDE-DEHYDROGENASE-RXN|EC:1.2.1.11|RHEA:24284|KEGG_REACTION:R02291 L-aspartate-4-semialdehyde:NADP+ oxidoreductase (phosphorylating)|aspartate semialdehyde dehydrogenase activity|L-aspartate-beta-semialdehyde:NADP oxidoreductase (phosporylating)|L-aspartate-beta-semialdehyde dehydrogenase activity|aspartic beta-semialdehyde dehydrogenase activity|aspartic semialdehyde dehydrogenase activity|ASA dehydrogenase activity Catalysis of the reaction: L-aspartate 4-semialdehyde + NADP(+) + phosphate = 4-phospho-L-aspartate + H(+) + NADPH. GO:0004072 aspartate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004072 MetaCyc:ASPARTATEKIN-RXN|RHEA:23776|EC:2.7.2.4|KEGG_REACTION:R00480 ATP:L-aspartate 4-phosphotransferase activity|aspartic kinase activity|aspartokinase activity|beta-aspartokinase activity Catalysis of the reaction: L-aspartate + ATP = 4-phospho-L-aspartate + ADP + H(+). GO:0102303 resveratrol 3,5-O-dimethyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102303 RHEA:32103|MetaCyc:RXN-12805|EC:2.1.1.240 Catalysis of the reaction: 2 S-adenosyl-L-methionine + trans-resveratrol <=> 2 S-adenosyl-L-homocysteine + pterostilbene + 2 H+. GO:0004075 biotin carboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004075 MetaCyc:BIOTIN-CARBOXYL-RXN|RHEA:13501|EC:6.3.4.14 biotin-carboxyl-carrier-protein:carbon-dioxide ligase (ADP-forming) activity|biotin carboxylase (component of acetyl CoA carboxylase) activity Catalysis of the reaction: ATP + biotin-carboxyl-carrier protein + CO2 = ADP + phosphate + carboxybiotin-carboxyl-carrier protein. GO:0102306 benzil reductase [(S)-benzoin-forming] activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102306 RHEA:25968|MetaCyc:RXN-12898|EC:1.1.1.320 Catalysis of the reaction: (S)-benzoin + NADP(3-) <=> benzil + NADPH(4-) + H+. GO:0102305 (13E)-labda-7,13-dien-15-ol synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102305 EC:3.1.7.10|RHEA:32075|MetaCyc:RXN-12892 Catalysis of the reaction: 2-cis,6-trans,10-trans-geranylgeranyl diphosphate + H2O <=> (13E)-labda-7,13-dien-15-ol + diphosphoric acid. GO:0004074 biliverdin reductase (NAD(P)+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004074 Reactome:R-HSA-189384|EC:1.3.1.24|MetaCyc:BILIVERDIN-REDUCTASE-RXN bilirubin:NAD(P)+ oxidoreductase activity Catalysis of the reaction: bilirubin + NAD(P)+ = biliverdin + NAD(P)H + H+. GO:0004080 biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004080 RHEA:11204|EC:6.3.4.10|MetaCyc:6.3.4.10-RXN holocarboxylase synthetase activity|propionyl-CoA holocarboxylase synthetase activity|biotin-propionyl coenzyme A carboxylase synthetase activity|biotin-propionyl-CoA-carboxylase (ATP-hydrolysing) synthetase activity|propionyl coenzyme A holocarboxylase synthetase activity|biotin:apo-propanoyl-CoA:carbon-dioxide ligase (ADP-forming) ligase (AMP-forming)|biotin-propionyl-CoA-carboxylase (ATP-hydrolysing) ligase activity|biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] synthetase activity Catalysis of the reaction: ATP + biotin + apo-(propanoyl-CoA:carbon-dioxide ligase (ADP-forming)) = AMP + diphosphate + (propanoyl-CoA:carbon-dioxide ligase (ADP-forming)). GO:0102308 erythromycin D 3''-o-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102308 RHEA:32651|MetaCyc:RXN-12924|EC:2.1.1.254 Catalysis of the reaction: S-adenosyl-L-methionine + erythromycin D <=> S-adenosyl-L-homocysteine + erythromycin B + H+. GO:0102307 erythromycin C 3''-o-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102307 RHEA:32647|MetaCyc:RXN-12923|EC:2.1.1.254 Catalysis of the reaction: S-adenosyl-L-methionine + erythromycin C <=> S-adenosyl-L-homocysteine + erythromycin A + H+. GO:0004082 bisphosphoglycerate mutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004082 EC:5.4.2.4|RHEA:17765|Reactome:R-HSA-6798335|MetaCyc:BISPHOSPHOGLYCERATE-MUTASE-RXN 2,3-diphosphoglycerate synthase activity|diphosphoglyceromutase activity|2,3-bisphosphoglycerate synthase activity|diphosphoglycerate mutase activity|bisphosphoglyceromutase|3-phospho-D-glycerate 1,2-phosphomutase activity|bisphosphoglycerate synthase activity|2,3-diphosphoglycerate mutase activity|BPGM activity|2,3-bisphosphoglycerate mutase activity|biphosphoglycerate synthase activity|2,3-diphosphoglyceromutase activity|glycerate phosphomutase activity|diphosphoglyceric mutase activity|DPGM Catalysis of the reaction: 3-phospho-D-glyceroyl phosphate = 2,3-bisphospho-D-glycerate. GO:0102309 dTDP-4-oxo-2,6-dideoxy-D-glucose 4-ketoreductase (dTDP-D-oliose producing) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102309 MetaCyc:RXN-12930 Catalysis of the reaction: dTDP-D-oliose + NADP <=> dTDP-4-dehydro-2,6-dideoxy-D-glucose + NADPH + H+. GO:0004081 bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004081 Reactome:R-HSA-5696197|RHEA:22484|MetaCyc:3.6.1.17-RXN|EC:3.6.1.17 Ap4Aase activity|diguanosinetetraphosphatase (asymmetrical) activity|dinucleoside tetraphosphatase activity|bis(5'-guanosyl)-tetraphosphatase activity|Ap(4)Aase activity|1-P,4-P-bis(5'-nucleosyl)-tetraphosphate nucleotidohydrolase activity|diadenosine 5',5'''-P1,P4-tetraphosphate hydrolase|diadenosine P1,P4-tetraphosphatase activity|dinucleosidetetraphosphatase (asymmetrical) activity|Ap(4)A hydrolase activity|diadenosinetetraphosphatase (asymmetrical) activity|diadenosine 5',5'''-P(1),P(4)-tetraphosphate asymmetrical hydrolase activity|bis(5'-adenosyl)-tetraphosphatase activity|P1,P4-bis(5'-nucleosyl)-tetraphosphate nucleotidohydrolase activity|diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase activity|Ap4A hydrolase activity Catalysis of the reaction: P(1),P(4)-bis(5'-nucleosyl)tetraphosphate + H2O = NTP + NMP. Acts on bis(5'-guanosyl)-, bis(5'-xanthosyl)-, bis(5'-adenosyl)- and bis(5'-uridyl)-tetraphosphate. GO:0018690 4-methoxybenzoate monooxygenase (O-demethylating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018690 KEGG_REACTION:R01306|MetaCyc:1.14.99.15-RXN|UM-BBD_reactionID:r0154|RHEA:18613|EC:1.14.99.15 piperonylate-4-O-demethylase activity|4-methoxybenzoate,hydrogen-donor:oxygen oxidoreductase (O-demethylating)|4-methoxybenzoate O-demethylase activity|4-methoxybenzoate monooxygenase activity|4-methoxybenzoate 4-monooxygenase (O-demethylating)|p-anisic O-demethylase activity Catalysis of the reaction: 4-methoxybenzoate + AH(2) + O(2) = 4-hydroxybenzoate + A + formaldehyde + H(2)O. GO:0004048 anthranilate phosphoribosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004048 EC:2.4.2.18|RHEA:11768|MetaCyc:PRTRANS-RXN|KEGG_REACTION:R01073 N-(5-phospho-D-ribosyl)-anthranilate:diphosphate phospho-alpha-D-ribosyltransferase activity|phosphoribosyl-anthranilate pyrophosphorylase activity|phosphoribosyl-anthranilate diphosphorylase activity|phosphoribosylanthranilate pyrophosphorylase activity|PRT|phosphoribosylanthranilate transferase activity|anthranilate phosphoribosylpyrophosphate phosphoribosyltransferase activity|anthranilate-PP-ribose-P phosphoribosyltransferase activity|anthranilate 5-phosphoribosylpyrophosphate phosphoribosyltransferase activity Catalysis of the reaction: N-(5-phospho-beta-D-ribosyl)anthranilate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + anthranilate. GO:0004047 aminomethyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004047 EC:2.1.2.10|Reactome:R-HSA-5693977|RHEA:16945|MetaCyc:GCVT-RXN protein-8-S-aminomethyldihydrolipoyllysine:tetrahydrofolate aminomethyltransferase (ammonia-forming) activity|tetrahydrofolate aminomethyltransferase activity|protein-S8-aminomethyldihydrolipoyllysine:tetrahydrofolate aminomethyltransferase (ammonia-forming) activity|T-protein|glycine synthase activity|S-aminomethyldihydrolipoylprotein:(6S)-tetrahydrofolate aminomethyltransferase (ammonia-forming) activity|glycine-cleavage system T-protein activity Catalysis of the reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + dihydrolipoylprotein. GO:0004049 anthranilate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004049 MetaCyc:ANTHRANSYN-RXN|EC:4.1.3.27|RHEA:21732 chorismate pyruvate-lyase (amino-accepting) activity|anthranilate synthetase activity Catalysis of the reaction: chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate. GO:0004044 amidophosphoribosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004044 RHEA:14905|EC:2.4.2.14|MetaCyc:PRPPAMIDOTRANS-RXN|Reactome:R-HSA-73815|KEGG_REACTION:R01072 5-phosphoribosyl-1-pyrophosphate amidotransferase activity|glutamine ribosylpyrophosphate 5-phosphate amidotransferase activity|phosphoribose pyrophosphate amidotransferase activity|glutamine 5-phosphoribosylpyrophosphate amidotransferase activity|glutamine phosphoribosyldiphosphate amidotransferase activity|5-phosphoribosylamine:diphosphate phospho-alpha-D-ribosyltransferase (glutamate-amidating)|glutamine phosphoribosylpyrophosphate amidotransferase activity|phosphoribosyl pyrophosphate amidotransferase activity|alpha-5-phosphoribosyl-1-pyrophosphate amidotransferase activity|phosphoribosyldiphosphate 5-amidotransferase activity|5'-phosphoribosylpyrophosphate amidotransferase activity|phosphoribosylpyrophosphate glutamyl amidotransferase activity|5-phosphororibosyl-1-pyrophosphate amidotransferase activity Catalysis of the reaction: 5-phospho-beta-D-ribosylamine + L-glutamate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + L-glutamine + H(2)O. GO:0004043 L-aminoadipate-semialdehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004043 RHEA:12308|EC:1.2.1.31|Reactome:R-HSA-70941|MetaCyc:1.2.1.31-RXN aminoadipate semialdehyde dehydrogenase activity|L-alpha-aminoadipate delta-semialdehyde:NAD oxidoreductase activity|alpha-aminoadipate reductase activity|2-aminoadipic semialdehyde dehydrogenase activity|2-aminoadipate semialdehyde dehydrogenase activity|AAR|aminoadipate-semialdehyde dehydrogenase activity|L-alpha-aminoadipate delta-semialdehyde oxidoreductase activity|L-2-aminoadipate-6-semialdehyde:NAD(P)+ 6-oxidoreductase|L-alpha-aminoadipate delta-semialdehyde:nicotinamide adenine dinucleotide oxidoreductase activity|alpha-aminoadipate-semialdehyde dehydrogenase activity Catalysis of the reaction: L-2-aminoadipate 6-semialdehyde + NADP+ + H2O = L-2-aminoadipate + NADPH + H+. GO:0004046 aminoacylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004046 EC:3.5.1.14|MetaCyc:AMINOACYLASE-RXN|Reactome:R-HSA-9638046|Reactome:R-HSA-5433074|RHEA:15565|Reactome:R-HSA-5579081 amido acid deacylase activity|hippurase activity|short acyl amidoacylase activity|acylase I activity|long acyl amidoacylase activity|benzamidase activity|aminoacylase I activity|L-aminoacylase activity|histozyme activity|dehydropeptidase II activity|N-acyl-L-amino-acid amidohydrolase activity|L-amino-acid acylase activity|alpha-N-acylaminoacid hydrolase activity Catalysis of the reaction: an N-acyl-L-amino acid + H2O = a carboxylate + an L-amino acid. GO:0004045 aminoacyl-tRNA hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004045 EC:3.1.1.29|RHEA:54448|MetaCyc:AMINOCYL-TRNA-HYDROLASE-RXN peptidyl-tRNA hydrolase activity|aminoacyl-transfer ribonucleate hydrolase activity|aminoacyl-tRNA aminoacylhydrolase activity|aminoacyl-tRNA hydrolase reaction|D-tyrosyl-tRNA hydrolase activity|N-substituted aminoacyl transfer RNA hydrolase activity Catalysis of the reaction: N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA. GO:0004040 amidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004040 MetaCyc:AMIDASE-RXN|EC:3.5.1.4|RHEA:12020|UM-BBD_enzymeID:e0068 acylase activity|acetamidase activity|acylamide amidohydrolase activity|amidohydrolase activity|fatty acylamidase activity|acylamidase activity|N-acetylaminohydrolase activity Catalysis of the reaction: a monocarboxylic acid amide + H2O = a monocarboxylate + NH3. GO:0004042 acetyl-CoA:L-glutamate N-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004042 Reactome:R-HSA-70542|KEGG_REACTION:R00259|EC:2.3.1.1|RHEA:24292|MetaCyc:N-ACETYLTRANSFER-RXN amino acid acetyltransferase activity|acetylglutamate acetylglutamate synthetase activity|amino-acid N-acetyltransferase activity|AGAS|N-acetylglutamate synthase activity Catalysis of the reaction: L-glutamate + acetyl-CoA = N-acetyl-L-glutamate + CoA + H(+). GO:0004041 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004041 GO:0018689 naphthalene disulfonate 1,2-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018689 UM-BBD_enzymeID:e0249|EC:1.14.99.- naphthalene disulphonate 1,2-dioxygenase activity Catalysis of the reaction: (1/2)-unsubstituted naphthalenoid-(2/1)-sulfonate + 2 H+ + 2 e- + O2 = 1,2-dihydroxynaphthalene derivative + HSO3(-). Substrates include naphthalene-1,6-disulfonate (forms 1,2-dihydroxynaphthalene-6-sulfonate), naphthalene-1-sulfonate (forms 1,2-dihydroxynaphthalene), naphthalene-2,6-disulfonate (forms 1,2-dihydroxynaphthalene-6-sulfonate) and naphthalene-2-sulfonate (forms 1,2-dihydroxynaphthalene). GO:0018688 DDT 2,3-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018688 EC:1.14.99.-|UM-BBD_reactionID:r0450 Catalysis of the reaction: 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane + O2 + 2 H+ + 2 e- = cis-2,3-dihydrodiol DDT. 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane is also known as DDT. GO:0018685 alkane 1-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018685 RHEA:19341|EC:1.14.15.3|UM-BBD_enzymeID:e0022|MetaCyc:ALKANE-1-MONOOXYGENASE-RXN alkane,reduced-rubredoxin:oxygen 1-oxidoreductase activity|1-hydroxylase activity|fatty acid omega-hydroxylase activity|alkane 1-hydroxylase activity|alkane monooxygenase activity|fatty acid (omega-1)-hydroxylase activity|omega-hydroxylase activity|alkane hydroxylase activity|lauric acid omega-hydroxylase activity Catalysis of the reaction: octane + reduced rubredoxin + O2 = 1-octanol + oxidized rubredoxin + H2O. GO:0018684 camphor 1,2-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018684 UM-BBD_enzymeID:e0302|EC:1.14.15.2|MetaCyc:CAMPHOR-12-MONOOXYGENASE-RXN (+)-camphor,reduced-rubredoxin:oxygen oxidoreductase (1,2-lactonizing)|camphor ketolactonase I activity|ketolactonase I|2,5-diketocamphane lactonizing enzyme activity|oxygenase, camphor 1,2-mono Catalysis of the reaction: (1R)-bornane-2,5-dione + reduced rubredoxin + O2 = 5-oxo-1,2-campholide + oxidized rubredoxin + H2O. GO:0018687 biphenyl 2,3-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018687 EC:1.14.12.18|RHEA:18165|UM-BBD_enzymeID:e0089|MetaCyc:1.14.12.18-RXN biphenyl,NADH:oxygen oxidoreductase (2,3-hydroxylating)|biphenyl dioxygenase activity Catalysis of the reaction: biphenyl + NADH + H+ + O2 = (2R,3S)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+. This reaction requires Fe2+. GO:0018686 6-hydroxy pseudo-oxynicotine monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018686 UM-BBD_reactionID:r0480|EC:1.14.18.- Catalysis of the reaction: 2 6-hydroxypseudooxynicotine + O2 = 2 2,6-dihydroxypseudooxynicotine. GO:0018681 deisopropylatrazine monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018681 EC:1.14.15.-|KEGG_REACTION:R05567 Catalysis of the reaction: 2 deisopropylatrazine + O2 = 2 acetaldehyde + 2 deisopropyldeethylatrazine. GO:0018680 deethylatrazine monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018680 EC:1.14.15.-|UM-BBD_reactionID:r0128 Catalysis of the reaction: 2 deethylatrazine + O2 = 2 CH3COCH3 + 2 deisopropyldeethylatrazine. GO:0018683 camphor 5-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018683 UM-BBD_enzymeID:e0300|EC:1.14.15.1|RHEA:13525|MetaCyc:R541-RXN D-camphor-exo-hydroxylase activity|bornanone 5-exo-hydroxylase activity|camphor methylene hydroxylase activity|camphor hydroxylase activity|2-bornanone 5-exo-hydroxylase activity|(+)-camphor,reduced putidaredoxin:oxygen oxidoreductase (5-hydroxylating)|camphor 5-exohydroxylase activity|camphor 5-exo-methylene hydroxylase activity|methylene monooxygenase activity|d-camphor monooxygenase activity|methylene hydroxylase activity|cytochrome p450-cam activity|camphor 5-exo-hydroxylase activity Catalysis of the reaction: (+)-camphor + putidaredoxin + O2 = (+)-exo-5-hydroxycamphor + oxidized putidaredoxin + H2O. GO:0018682 atrazine N-dealkylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018682 EC:1.14.15.-|UM-BBD_reactionID:r0127|MetaCyc:R461-RXN atrazine monooxygenase activity Catalysis of the reaction: atrazine + O2 + 2 H+ = deethylatrazine + acetaldehyde + H2O. GO:0004059 aralkylamine N-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004059 Reactome:R-HSA-209792|MetaCyc:ARALKYLAMINE-N-ACETYLTRANSFERASE-RXN|EC:2.3.1.87|RHEA:20497 serotonin N-acetyltransferase activity|arylalkylamine N-acetyltransferase activity|serotonin acetylase activity|melatonin rhythm enzyme activity|acetyl-CoA:2-arylethylamine N-acetyltransferase activity|AANAT activity|serotonin acetyltransferase activity Catalysis of the reaction: acetyl-CoA + an aralkylamine = CoA + an N-acetylaralkylamine. GO:0004058 aromatic-L-amino-acid decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004058 MetaCyc:AROMATIC-L-AMINO-ACID-DECARBOXYLASE-RXN|Reactome:R-HSA-209859|EC:4.1.1.28|Reactome:R-HSA-209924 aromatic-L-amino-acid carboxy-lyase (tryptamine-forming)|hydroxytryptophan decarboxylase activity|aromatic amino acid decarboxylase activity|5-hydroxytryptophan decarboxylase activity|tryptophan decarboxylase activity|aromatic-L-amino-acid carboxy-lyase activity|DOPA decarboxylase activity|L-DOPA decarboxylase activity Catalysis of the reaction: L-amino acid + H+ = R-H + CO2. GO:0004055 argininosuccinate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004055 MetaCyc:ARGSUCCINSYN-RXN|RHEA:10932|EC:6.3.4.5|Reactome:R-HSA-70577 citrulline--aspartate ligase activity|L-citrulline:L-aspartate ligase (AMP-forming)|argininosuccinate synthetase activity|arginosuccinate synthetase activity|arginine succinate synthetase activity|argininosuccinic acid synthetase activity Catalysis of the reaction: ATP + L-citrulline + L-aspartate = AMP + diphosphate + (N(omega)-L-arginino)succinate. GO:0004054 arginine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004054 MetaCyc:ARGININE-KINASE-RXN|KEGG_REACTION:R00554|RHEA:22940|EC:2.7.3.3 adenosine 5'-triphosphate:L-arginine|adenosine 5'-triphosphate-arginine phosphotransferase activity|arginine phosphokinase activity|ATP:L-arginine N-phosphotransferase activity Catalysis of the reaction: L-arginine + ATP = N(omega)-phospho-L-arginine + ADP + 2 H(+). GO:0004057 arginyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004057 MetaCyc:ARGINYLTRANSFERASE-RXN|RHEA:10208|EC:2.3.2.8 arginine transferase activity|arginyl-tRNA-protein transferase activity|arginyl-transfer ribonucleate-protein transferase activity|arginyl-tRNA--protein transferase activity|arginyl-tRNA protein transferase activity|L-arginyl-tRNA:protein arginyltransferase activity|arginyl-transfer ribonucleate-protein aminoacyltransferase activity Catalysis of the reaction: L-arginyl-tRNA + protein = tRNA + L-arginyl-protein. GO:0004056 argininosuccinate lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004056 RHEA:24020|MetaCyc:ARGSUCCINLYA-RXN|EC:4.3.2.1|Reactome:R-HSA-70573 argininosuccinic acid lyase activity|2-(omega-N-L-arginino)succinate arginine-lyase (fumarate-forming)|arginosuccinase activity|2-(Nomega-L-arginino)succinate arginine-lyase (fumarate-forming)|N-(L-argininosuccinate) arginine-lyase activity|arginine-succinate lyase activity|omega-N-(L-arginino)succinate arginine-lyase activity Catalysis of the reaction: N-(L-arginino)succinate = fumarate + L-arginine. GO:0004051 arachidonate 5-lipoxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004051 Reactome:R-HSA-9020264|Reactome:R-HSA-9025999|Reactome:R-HSA-9020282|Reactome:R-HSA-9025995|Reactome:R-HSA-9018859|Reactome:R-HSA-9026005|Reactome:R-HSA-9020256|Reactome:R-HSA-9027624|EC:1.13.11.34|Reactome:R-HSA-9018894|Reactome:R-HSA-9027633|Reactome:R-HSA-266051|Reactome:R-HSA-9020278|Reactome:R-HSA-9020277|RHEA:32307|Reactome:R-HSA-265296|MetaCyc:ARACHIDONATE-5-LIPOXYGENASE-RXN|Reactome:R-HSA-9020255|Reactome:R-HSA-9020259|Reactome:R-HSA-9018858|Reactome:R-HSA-9027628|Reactome:R-HSA-9025996|Reactome:R-HSA-9026405|Reactome:R-HSA-9024997|Reactome:R-HSA-9020251|Reactome:R-HSA-9018863 leukotriene A4 synthase|C-5-lipoxygenase activity|arachidonic acid 5-lipoxygenase activity|leukotriene-A4 synthase activity|delta(5)-lipoxygenase activity|5Delta-lipoxygenase activity|5-delta-lipoxygenase activity|arachidonic 5-lipoxygenase activity|delta5-lipoxygenase activity|LTA synthase activity|arachidonate:oxygen 5-oxidoreductase activity|leukotriene-A(4) synthase activity|5-lipoxygenase activity Catalysis of the reaction: arachidonate + O2 = (6E,8Z,11Z,14Z)-(5S)-5-hydroperoxycosa-6,8,11,14-tetraenoate. GO:0004050 obsolete apyrase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004050 apyrase activity OBSOLETE. Catalysis of the reaction: ATP + 2 H2O = AMP + 2 phosphate. GO:0004053 arginase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004053 MetaCyc:ARGINASE-RXN|Reactome:R-HSA-452036|Reactome:R-HSA-70569|RHEA:20569|EC:3.5.3.1 L-arginase activity|arginine transamidinase activity|canavanase activity|arginine amidinase activity|L-arginine amidinohydrolase activity Catalysis of the reaction: L-arginine + H2O = L-ornithine + urea. GO:0004052 arachidonate 12(S)-lipoxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004052 Reactome:R-HSA-9026007|Reactome:R-HSA-9024983|Reactome:R-HSA-9025957|EC:1.13.11.31|Reactome:R-HSA-9026006|Reactome:R-HSA-2161950|RHEA:10428|MetaCyc:ARACHIDONATE-12-LIPOXYGENASE-RXN|KEGG_REACTION:R01596|Reactome:R-HSA-2161964|Reactome:R-HSA-2161948 leukotriene A4 synthase|12-lipoxygenase activity|delta12-lipoxygenase activity|C-12 lipoxygenase activity|arachidonate:oxygen 12-oxidoreductase activity|12Delta-lipoxygenase activity|12S-lipoxygenase activity|LTA4 synthase activity Catalysis of the reaction: arachidonate + O(2) = (5Z,8Z,10E,12S,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoate. GO:0004060 arylamine N-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004060 MetaCyc:ARYLAMINE-N-ACETYLTRANSFERASE-RXN|RHEA:16613|EC:2.3.1.5|Reactome:R-HSA-174967|Reactome:R-HSA-174963|UM-BBD_enzymeID:e0341 4-aminobiphenyl N-acetyltransferase activity|acetyl-CoA:arylamine N-acetyltransferase activity|beta-naphthylamine N-acetyltransferase activity|2-naphthylamine N-acetyltransferase activity|p-aminosalicylate N-acetyltransferase activity|indoleamine N-acetyltransferase activity|arylamine acetyltransferase activity|arylamine acetylase activity|acetyl CoA-arylamine N-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + an arylamine = CoA + an N-acetylarylamine. GO:0018699 1,1,1-trichloroethane reductive dehalogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018699 UM-BBD_reactionID:r1007|EC:1.97.1.- Catalysis of the reaction: 1,1,1-trichloroethane + 2 H+ + 2 e- = 1,1-dichloroethane + HCl. GO:0018696 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018696 GO:0018695 4-cresol dehydrogenase (hydroxylating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018695 EC:1.17.9.1|UM-BBD_reactionID:r0272|RHEA:15141|MetaCyc:1.17.99.1-RXN p-cresol-(acceptor) oxidoreductase (hydroxylating) activity|4-cresol dehydrogenase activity|p-cresol methylhydroxylase activity|4-cresol:acceptor oxidoreductase (methyl-hydroxylating) Catalysis of the reaction: 4-cresol + acceptor + H2O = 4-hydroxybenzaldehyde + reduced acceptor. GO:0018698 vinyl chloride reductive dehalogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018698 MetaCyc:VCREDCHLOR-RXN|UM-BBD_reactionID:r0352|EC:1.97.1.- Catalysis of the reaction: vinyl chloride + 2 H+ + 2 e- = HCl + ethene. GO:0018697 carbonyl sulfide nitrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018697 UM-BBD_reactionID:r0600|EC:1.18.6.1 carbonyl sulphide nitrogenase activity Catalysis of the reaction: carbonyl sulfide + 2 H+ + 2 e- = hydrogen sulfide + carbon monoxide. GO:0018692 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018692 GO:0018691 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018691 GO:0018694 p-cymene methyl hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018694 EC:1.17.99.-|UM-BBD_reactionID:r0392|MetaCyc:RXN-661|RHEA:51604 Catalysis of the reaction: p-cymene + NADH + O2 = NAD+ + OH- + p-cumic alcohol. GO:0018693 ethylbenzene hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018693 EC:1.17.99.2|UM-BBD_reactionID:r0234|KEGG_REACTION:R05745|RHEA:17897|MetaCyc:RXN-1301 ethylbenzene dehydrogenase activity|ethylbenzene:(acceptor) oxidoreductase activity Catalysis of the reaction: A + ethylbenzene + H(2)O = (S)-1-phenylethanol + AH(2). GO:0004029 aldehyde dehydrogenase (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004029 Reactome:R-HSA-5696091|UM-BBD_enzymeID:e0024|Reactome:R-HSA-6813749|MetaCyc:ALDHDEHYDROG-RXN|Wikipedia:Aldehyde_dehydrogenase_(NAD+)|Reactome:R-HSA-389609|Reactome:R-HSA-71691|Reactome:R-HSA-71723|Reactome:R-HSA-6808487|Reactome:R-HSA-6808496|Reactome:R-HSA-5692261|EC:1.2.1.3|RHEA:16185|Reactome:R-HSA-380608 aldehyde:NAD+ oxidoreductase activity|m-methylbenzaldehyde dehydrogenase activity|NAD-aldehyde dehydrogenase activity|NAD-dependent aldehyde dehydrogenase activity|CoA-independent aldehyde dehydrogenase activity|propionaldehyde dehydrogenase activity|aldehyde dehydrogenase (NAD+)|NAD-dependent 4-hydroxynonenal dehydrogenase activity|NAD-linked aldehyde dehydrogenase activity Catalysis of the reaction: an aldehyde + NAD+ + H2O = an acid + NADH + H+. GO:0004026 alcohol O-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004026 MetaCyc:ALCOHOL-O-ACETYLTRANSFERASE-RXN|EC:2.3.1.84|RHEA:17229 alcohol acetyltransferase activity|AATASE activity|acetyl-CoA:alcohol O-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + an alcohol = CoA + an acetyl ester. GO:0004025 alcohol dehydrogenase activity, iron-dependent biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004025 Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+, requiring the presence of iron. GO:0004028 3-chloroallyl aldehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004028 UM-BBD_enzymeID:e0432|Reactome:R-HSA-71260 Catalysis of the reaction: 3-chloroallyl aldehyde + H2O = 2 H+ + 2 e- + 3-chloroacrylic acid. GO:0004027 alcohol sulfotransferase activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0004027 Reactome:R-HSA-176609|RHEA:22552|EC:2.8.2.2|Reactome:R-HSA-176494|MetaCyc:ALCOHOL-SULFOTRANSFERASE-RXN delta5-3beta-hydroxysteroid sulfokinase activity|5alpha-androstenol sulfotransferase activity|3beta-hydroxysteroid sulfotransferase activity|sterol sulfokinase activity|dehydroepiandrosterone sulfotransferase activity|estrogen sulfokinase activity|3'-phosphoadenylyl-sulfate:alcohol sulfotransferase activity|HST|alcohol/hydroxysteroid sulfotransferase activity|steroid alcohol sulfotransferase|sterol sulfotransferase activity|hydroxysteroid sulfotransferase activity|estrogen sulfotransferase|alcohol sulphotransferase activity|3-hydroxysteroid sulfotransferase activity|3beta-hydroxy steroid sulfotransferase activity|steroid sulfokinase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + an alcohol = adenosine 3',5'-bisphosphate + an alkyl sulfate. GO:0004022 alcohol dehydrogenase (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004022 UM-BBD_enzymeID:e0023|MetaCyc:ALCOHOL-DEHYDROG-GENERIC-RXN|RHEA:10740|Reactome:R-HSA-2162078|EC:1.1.1.1 alcohol:NAD+ oxidoreductase|aliphatic alcohol dehydrogenase|NADH-alcohol dehydrogenase|NADH-aldehyde dehydrogenase|ADH|NAD-dependent alcohol dehydrogenase|yeast alcohol dehydrogenase|ethanol dehydrogenase|primary alcohol dehydrogenase|aldo-keto reductase (NAD) activity|aldehyde dehydrogenase (NAD) activity|alcohol dehydrogenase activity|NAD-specific aromatic alcohol dehydrogenase Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+. GO:0004021 L-alanine:2-oxoglutarate aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004021 KEGG_REACTION:R00258|EC:2.6.1.2|RHEA:19453|Reactome:R-HSA-507749|MetaCyc:ALANINE-AMINOTRANSFERASE-RXN|Reactome:R-HSA-70524|Reactome:R-HSA-507775|Reactome:R-HSA-70523 glutamic--alanine transaminase activity|pyruvate-glutamate transaminase activity|alanine-pyruvate aminotransferase activity|glutamic--pyruvic transaminase activity|GPT|ALT|glutamic acid-pyruvic acid transaminase activity|pyruvate-alanine aminotransferase activity|glutamic-pyruvic aminotransferase activity|L-alanine aminotransferase activity|alanine aminotransferase activity|alanine-alpha-ketoglutarate aminotransferase activity|beta-alanine aminotransferase|L-alanine-alpha-ketoglutarate aminotransferase activity|pyruvate transaminase activity|alanine transaminase activity|L-alanine transaminase activity Catalysis of the reaction: 2-oxoglutarate + L-alanine = L-glutamate + pyruvate. GO:0004024 alcohol dehydrogenase activity, zinc-dependent biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004024 Reactome:R-HSA-71707 Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+, requiring the presence of zinc. GO:0004023 alcohol dehydrogenase activity, metal ion-independent biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004023 Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+; can proceed in the absence of a metal ion. GO:0004020 adenylylsulfate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004020 Reactome:R-HSA-3560785|Reactome:R-HSA-174389|EC:2.7.1.25|MetaCyc:ADENYLYLSULFKIN-RXN|RHEA:24152 adenylyl-sulphate kinase activity|adenosine phosphosulfate kinase activity|adenosine-5'-phosphosulfate-3'-phosphokinase activity|5'-phosphoadenosine sulfate kinase activity|adenosine 5'-phosphosulfate kinase activity|adenosine-5'-phosphosulfate 3'-phosphotransferase activity|ATP:adenylyl-sulfate 3'-phosphotransferase activity|APS kinase activity|adenylylsulfate kinase (phosphorylating)|adenylyl-sulfate kinase activity|adenosine phosphosulfokinase activity|adenosine-5'-phosphosulphate 3'-phosphotransferase activity Catalysis of the reaction: ATP + adenylylsulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate. GO:0018667 cyclohexanone monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018667 RHEA:24068|EC:1.14.13.22|MetaCyc:CYCLOHEXANONE-MONOOXYGENASE-RXN|UM-BBD_reactionID:r0166 cyclohexanone:NADPH:oxygen oxidoreductase (lactone-forming)|cyclohexanone 1,2-monooxygenase activity|cyclohexanone oxygenase activity|cyclohexanone:NADPH:oxygen oxidoreductase (6-hydroxylating, 1,2-lactonizing) activity Catalysis of the reaction: cyclohexanone + NADPH + H+ + O2 = 6-hexanolide + NADP+ + H2O. GO:0018666 2,4-dichlorophenol 6-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018666 MetaCyc:24-DICHLOROPHENOL-6-MONOOXYGENASE-RXN|EC:1.14.13.20|UM-BBD_enzymeID:e0152|RHEA:20920 2,4-dichlorophenol hydroxylase activity|2,4-dichlorophenol,NADPH:oxygen oxidoreductase (6-hydroxylating)|2,4-dichlorophenol monooxygenase activity Catalysis of the reaction: 2,4-dichlorophenol + NADPH + H+ + O2 = 3,5-dichlorocatechol + NADP+ + H2O. GO:0018669 3-hydroxybenzoate 6-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018669 RHEA:22692|MetaCyc:3-HYDROXYBENZOATE-6-MONOOXYGENASE-RXN|EC:1.14.13.24|UM-BBD_reactionID:r0402|KEGG_REACTION:R02589 3-hydroxybenzoate 6-hydroxylase activity|m-hydroxybenzoate 6-hydroxylase activity|3-hydroxybenzoate,NADH:oxygen oxidoreductase (6-hydroxylating)|3-hydroxybenzoic acid-6-hydroxylase activity Catalysis of the reaction: 3-hydroxybenzoate + H(+) + NADH + O(2) = 2,5-dihydroxybenzoate + H(2)O + NAD(+). GO:0018668 3-hydroxybenzoate 4-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018668 UM-BBD_reactionID:r0153|RHEA:11480|MetaCyc:3-HYDROXYBENZOATE-4-MONOOXYGENASE-RXN|EC:1.14.13.23|KEGG_REACTION:R01628 3-hydroxybenzoate,NADPH:oxygen oxidoreductase (4-hydroxylating)|3-hydroxybenzoate 4-hydroxylase activity Catalysis of the reaction: 3-hydroxybenzoate + H(+) + NADPH + O(2) = 3,4-dihydroxybenzoate + H(2)O + NADP(+). GO:0018663 2,6-dihydroxypyridine 3-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018663 MetaCyc:1.14.13.10-RXN|KEGG_REACTION:R04130|EC:1.14.13.10|RHEA:16917|UM-BBD_reactionID:r0479 2,6-dihydroxypyridine oxidase activity|2,6-dihydroxypyridine,NADH:oxygen oxidoreductase (3-hydroxylating) Catalysis of the reaction: 2,6-dihydroxypyridine + H(+) + NADH + O(2) = 2,3,6-trihydroxypyridine + H(2)O + NAD(+). GO:0018662 phenol 2-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018662 UM-BBD_enzymeID:e0208|RHEA:17061|EC:1.14.13.7|MetaCyc:PHENOL-2-MONOOXYGENASE-RXN phenol hydroxylase activity|phenol o-hydroxylase activity|phenol,NADPH:oxygen oxidoreductase (2-hydroxylating) Catalysis of the reaction: phenol + NADPH + H+ + O2 = catechol + NADP+ + H2O. GO:0018665 4-hydroxyphenylacetate 1-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018665 EC:1.14.13.18|MetaCyc:1.14.13.18-RXN|UM-BBD_reactionID:r0300 4-hydroxyphenylacetate 1-hydroxylase activity|4-hydroxyphenylacetic 1-hydroxylase activity|4-hydroxyphenylacetate,NAD(P)H:oxygen oxidoreductase (1-hydroxylating)|4-HPA 1-hydroxylase activity|4-hydroxyphenyl-acetate 1-hydroxylase activity Catalysis of the reaction: 4-hydroxyphenylacetate + NADPH + H+ + O2 = homogentisate + NADP+ + H2O. GO:0018664 benzoate 4-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018664 MetaCyc:BENZOATE-4-MONOOXYGENASE-RXN|KEGG_REACTION:R01295|RHEA:18033|UM-BBD_reactionID:r0623|EC:1.14.14.92 p-hydroxybenzoate hydroxylase activity|benzoate-p-hydroxylase activity|benzoic acid 4-hydroxylase activity|benzoate-para-hydroxylase activity|benzoate,NADPH:oxygen oxidoreductase (4-hydroxylating)|benzoate 4-hydroxylase activity|4-hydroxybenzoic hydroxylase activity|benzoic 4-hydroxylase activity Catalysis of the reaction: benzoate + H(+) + NADPH + O(2) = 4-hydroxybenzoate + H(2)O + NADP(+). GO:0018661 orcinol 2-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018661 RHEA:19601|UM-BBD_reactionID:r0092|EC:1.14.13.6|MetaCyc:ORCINOL-2-MONOOXYGENASE-RXN|KEGG_REACTION:R02830 orcinol,NADH:oxygen oxidoreductase (2-hydroxylating)|orcinol hydroxylase activity Catalysis of the reaction: H(+) + NADH + O(2) + orcinol = 2,3,5-trihydroxytoluene + H(2)O + NAD(+). GO:0018660 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018660 RHEA:16681|EC:1.14.13.-|KEGG_REACTION:R02698 p-hydroxyphenylacetate 3-hydroxylase activity|4 HPA 3-hydroxylase activity|4-hydroxyphenylacetate 3-hydroxylase activity|4-hydroxyphenylacetate 3-monooxygenase activity|p-hydroxyphenylacetate hydroxylase activity Catalysis of the reaction: 4-hydroxyphenylacetate + NADH + H+ + O2 = 3,4-dihydroxyphenylacetate + NAD+ + H2O. GO:0004037 allantoicase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004037 EC:3.5.3.4|MetaCyc:ALLANTOICASE-RXN|RHEA:11016|KEGG_REACTION:R02422 allantoate amidinohydrolase activity|allantoine amidinohydrolase activity Catalysis of the reaction: allantoate + H(2)O = (S)-ureidoglycolate + urea. GO:0004036 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004036 GO:0004039 allophanate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004039 EC:3.5.1.54|RHEA:19029|UM-BBD_reactionID:r0848|MetaCyc:ALLOPHANATE-HYDROLASE-RXN|KEGG_REACTION:R00005 allophanate lyase activity|urea-1-carboxylate amidohydrolase activity Catalysis of the reaction: H(2)O + 3 H(+) + urea-1-carboxylate = 2 CO(2) + 2 NH(4)(+). GO:0004038 allantoinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004038 RHEA:17029|EC:3.5.2.5|MetaCyc:ALLANTOINASE-RXN (S)-allantoin amidohydrolase activity Catalysis of the reaction: allantoin + H2O = allantoate. GO:0004033 aldo-keto reductase (NADP) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004033 Reactome:R-HSA-193824|Reactome:R-HSA-193755|Reactome:R-HSA-193821|Reactome:R-HSA-5423637|Reactome:R-HSA-9027531|Reactome:R-HSA-193800|Reactome:R-HSA-9027562|Reactome:R-HSA-192033|Reactome:R-HSA-198845|Reactome:R-HSA-192067|Reactome:R-HSA-192160|Reactome:R-HSA-9027598|Reactome:R-HSA-193746|Reactome:R-HSA-193781|Reactome:R-HSA-192036|Reactome:R-HSA-2855252|Reactome:R-HSA-193841|Reactome:R-HSA-9027600|Reactome:R-HSA-193758|Reactome:R-HSA-5692232 aldo-keto reductase activity|aldo-keto reductase (NADP+) activity|NADPH-dependent aldo-keto reductase activity|alcohol dehydrogenase (NADP+) activity Catalysis of the reaction: an alcohol + NADP+ = an aldehyde or a ketone + NADPH + H+. GO:0004032 alditol:NADP+ 1-oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004032 MetaCyc:ALDEHYDE-REDUCTASE-RXN|EC:1.1.1.21|Reactome:R-HSA-5652172|Reactome:R-HSA-196060|RHEA:12789|KEGG_REACTION:R02820 polyol dehydrogenase (NADP(+)) activity|aldose reductase activity|aldehyde reductase activity Catalysis of the reaction: an alditol + NADP+ = an aldose + NADPH + H+. GO:0004035 alkaline phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004035 Reactome:R-HSA-8878787|EC:3.1.3.1|MetaCyc:ALKAPHOSPHA-RXN alkaline phosphomonoesterase activity|glycerophosphatase activity|orthophosphoric-monoester phosphohydrolase (alkaline optimum)|phosphomonoesterase activity|alkaline phosphohydrolase activity|alkaline phenyl phosphatase activity|phosphate-monoester phosphohydrolase (alkaline optimum) Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum. GO:0004034 aldose 1-epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004034 RHEA:10264|EC:5.1.3.3|MetaCyc:ALDOSE-1-EPIMERASE-RXN mutarotase activity|aldose mutarotase activity Catalysis of the reaction: alpha-D-glucose = beta-D-glucose. Also acts on L-arabinose, D-xylose, D-galactose, maltose and lactose. GO:0004031 aldehyde oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004031 EC:1.2.3.1|RHEA:16829|MetaCyc:ALDEHYDE-OXIDASE-RXN|Reactome:R-HSA-3204311 aldehyde:oxygen oxidoreductase activity|quinoline oxidase activity Catalysis of the reaction: an aldehyde + H2O + O2 = a carboxylic acid + hydrogen peroxide. GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004030 Reactome:R-HSA-6808464|EC:1.2.1.5|Reactome:R-HSA-5692283|MetaCyc:ALDEHYDE-DEHYDROGENASE-NADP+-RXN|Reactome:R-HSA-5696080 aldehyde:NAD(P)+ oxidoreductase activity|ALDH Catalysis of the reaction: an aldehyde + NAD(P)+ + H2O = an acid + NAD(P)H + H+. GO:0018678 4-hydroxybenzoate 1-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018678 EC:1.14.13.64|UM-BBD_reactionID:r0752|MetaCyc:1.14.13.64-RXN 4-hydroxybenzoate 1-monooxygenase activity|4-hydroxybenzoate,NAD(P)H:oxygen oxidoreductase (1-hydroxylating, decarboxylating) Catalysis of the reaction: 4-hydroxybenzoate + NADPH + H+ + O2 = hydroquinone + NADP+ + H2O + CO2. GO:0018677 pentachlorophenol monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018677 EC:1.14.13.50|MetaCyc:PCP4MONO-RXN|RHEA:18685|UM-BBD_enzymeID:e0148 PCP hydroxylase activity|pentachlorophenol dehalogenase activity|pentachlorophenol 4-monooxygenase activity|pentachlorophenol hydroxylase activity|pentachlorophenol dechlorinase activity|PCB 4-monooxygenase activity|PCB4MO activity|pentachlorophenol,NADPH:oxygen oxidoreductase (hydroxylating, dechlorinating)|PcpB Catalysis of the reaction: pentachlorophenol + NADPH + H+ + O2 = tetrachlorohydroquinone + NADP+ + chloride. GO:0018679 dibenzothiophene-5,5-dioxide monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018679 EC:1.14.14.-|UM-BBD_reactionID:r0235|MetaCyc:RXN-623 Catalysis of the reaction: dibenzothiophene-5,5-dioxide + O2 + 2 NADH + H+ = 2 NAD+ + H2O + 2'-hydroxybiphenyl-2-sulfinate. GO:0018674 (S)-limonene 3-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018674 UM-BBD_reactionID:r0739|EC:1.14.14.99|KEGG_REACTION:R02469|RHEA:15129|MetaCyc:--LIMONENE-3-MONOOXYGENASE-RXN (-)-limonene 3-hydroxylase activity|limonene 3-hydroxylase activity|(-)-limonene 3-monooxygenase activity|(-)-limonene,NADPH:oxygen oxidoreductase (3-hydroxylating) activity|(S)-limonene,NADPH:oxygen oxidoreductase (3-hydroxylating) Catalysis of the reaction: (4S)-limonene + H(+) + NADPH + O(2) = (1S,6R)-isopiperitenol + H(2)O + NADP(+). GO:0018673 anthraniloyl-CoA monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018673 EC:1.14.13.40|UM-BBD_reactionID:r0568|MetaCyc:ANTHRANILOYL-COA-MONOOXYGENASE-RXN 2-aminobenzoyl-CoA,NAD(P)H:oxygen oxidoreductase (de-aromatizing)|2-aminobenzoyl-CoA monooxygenase/reductase activity|anthraniloyl coenzyme A reductase activity Catalysis of the reaction: 2-aminobenzoyl-CoA + 2 NADPH + 2 H+ + O2 = 2-amino-5-oxocyclohex-1-enecarboxyl-CoA + H2O + 2 NADP+. GO:0018676 (S)-limonene 7-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018676 UM-BBD_reactionID:r0728|EC:1.14.14.52|RHEA:23432|MetaCyc:--LIMONENE-7-MONOOXYGENASE-RXN|KEGG_REACTION:R02470 (-)-limonene 7-monooxygenase activity Catalysis of the reaction: (4S)-limonene + H(+) + NADPH + O(2) = (4S)-perillyl alcohol + H(2)O + NADP(+). GO:0018675 (S)-limonene 6-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018675 UM-BBD_reactionID:r0713|EC:1.14.14.51|RHEA:17945|MetaCyc:--LIMONENE-6-MONOOXYGENASE-RXN (-)-limonene 6-hydroxylase activity|(-)-limonene,NADPH:oxygen oxidoreductase (6-hydroxylating) activity|limonene 6-hydroxylase activity|(-)-limonene 6-monooxygenase activity|(S)-limonene,NADPH:oxygen oxidoreductase (6-hydroxylating) Catalysis of the reaction: (-)-limonene + NADPH + H+ + O2 = (-)-trans-carveol + NADP+ + H2O. GO:0018670 4-aminobenzoate 1-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018670 UM-BBD_reactionID:r0597|MetaCyc:4-AMINOBENZOATE-1-MONOOXYGENASE-RXN|EC:1.14.13.27 4-aminobenzoate monooxygenase activity|4-aminobenzoate dehydrogenase activity|4-aminobenzoate hydroxylase activity|4-aminobenzoate,NAD(P)H:oxygen oxidoreductase (1-hydroxylating, decarboxylating) Catalysis of the reaction: 4-aminobenzoate + NADPH + H+ + O2 = 4-hydroxyaniline + NADP+ + H2O + CO2. GO:0018672 anthranilate 3-monooxygenase (deaminating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018672 UM-BBD_reactionID:r0578|RHEA:21236|MetaCyc:1.14.13.35-RXN|KEGG_REACTION:R00980|EC:1.14.13.35 anthranilate 2,3-hydroxylase (deaminating) activity|anthranilate hydroxylase (deaminating) activity|anthranilate 2,3-dioxygenase (deaminating)|anthranilate hydroxylase activity|anthranilate,NADPH:oxygen oxidoreductase (3-hydroxylating, deaminating) Catalysis of the reaction: anthranilate + 2 H(+) + NADPH + O(2) = 2,3-dihydroxybenzoate + NADP(+) + NH(4)(+). GO:0018671 4-hydroxybenzoate 3-monooxygenase [NAD(P)H] activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018671 MetaCyc:1.14.13.33-RXN|RHEA:19473|EC:1.14.13.33 4-hydroxybenzoate,NAD(P)H:oxygen oxidoreductase (3-hydroxylating)|4-hydroxybenzoate 3-hydroxylase activity|4-hydroxybenzoate 3-monooxygenase (reduced nicotinamide adenine dinucleotide (phosphate))|4-hydroxybenzoate-3-hydroxylase activity Catalysis of the reaction: 4-hydroxybenzoate + NAD(P)H + H+ + O2 = 3,4-dihydroxybenzoate + NAD(P)+ + H2O. PR:000019996 somatoliberin proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000019996 GHRH/ClvPrd A somatoliberin that has been processed by proteolytic cleavage. PR:000019995 growth hormone receptor proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000019995 GHR/ClvPrd A growth hormone receptor that has been processed by proteolytic cleavage. GO:0102351 gamma-aminobutyrate transaminase (glyoxylate dependent) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102351 RHEA:32267|EC:2.6.1.96|MetaCyc:RXN-13328 Catalysis of the reaction: gamma-aminobutyric acid + 2-oxo monocarboxylic acid anion = 4-oxobutanoate + glycine. GO:0102350 trans-cerot-2-enoyl-CoA reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102350 MetaCyc:RXN-13309 Catalysis of the reaction: hexacosanoyl-CoA(4-) + NADP(3-) <=> trans-2-hexacosenoyl-CoA + NADPH + H+. GO:0102353 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0102353 PR:000019999 appetite-regulating hormone proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000019999 GHRL/ClvPrd An appetite-regulating hormone that has been processed by proteolytic cleavage. GO:0102352 phosphatidate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102352 MetaCyc:RXN-13336 Catalysis of the reaction: ATP + a 1,2-diacyl-sn-glycerol 3-phosphate = ADP + a 1,2-diacyl-sn-glycerol 3-diphosphate. GO:0102355 2-oxo-3-(5-oxofuran-2-ylidene)propanoate lactonase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102355 MetaCyc:RXN-13371|RHEA:33967|EC:3.1.1.91 Catalysis of the reaction: 2-oxo-3-(5-oxofuran-2-ylidene)propanoate + H2O <=> 3-maleylpyruvate + H+. GO:0102354 11-cis-retinol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102354 MetaCyc:RXN-13363|RHEA:54912 Catalysis of the reaction: 11-cis-retinol + NADP = 11-cis-retinal + NADPH + H+. GO:0102357 mithramycin dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102357 MetaCyc:RXN-13385 Catalysis of the reaction: mithramycin + NADP <=> mithramycin DK + NADPH + H+. GO:0043610 regulation of carbohydrate utilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043610 regulation of sugar utilization Any process that modulates the frequency, rate or extent of carbohydrate utilization. GO:0102356 isoitalicene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102356 MetaCyc:RXN-13373 Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> diphosphoric acid + (+)-isoitalicene. GO:0102359 daphnetin 4-O-beta-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102359 MetaCyc:RXN-13450|EC:2.4.1.126 Catalysis of the reaction: UDP-alpha-D-glucose + 7,8-dihydroxycoumarin <=> UDP + 4-O- beta -D-glucosyl-daphnetin + H+. GO:0102358 daphnetin-8-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102358 MetaCyc:RXN-13448 Catalysis of the reaction: S-adenosyl-L-methionine + 7,8-dihydroxycoumarin <=> S-adenosyl-L-homocysteine + 7-hydroxy-8-methoxycoumarin + H+. GO:0043616 keratinocyte proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043616 The multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. Keratinocytes are epidermal cells which synthesize keratin and undergo a characteristic change as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. GO:0043615 astrocyte cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043615 astrocytic glial cell migration|astrocyte migration The orderly movement of an astrocyte, a class of large neuroglial (macroglial) cells in the central nervous system, the largest and most numerous neuroglial cells in the brain and spinal cord. GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043618 Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). GO:0043617 cellular response to sucrose starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043617 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sucrose. GO:0043612 isoprene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043612 2-methyl-1,3-butadiene biosynthetic process|2-methyl-1,3-butadiene biosynthesis|hemiterpene biosynthetic process|hemiterpene biosynthesis The chemical reactions and pathways resulting in the formation of isoprene, C5H8. CHEBI:78022 1-stearoyl-2-(alpha-linolenoyl)-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78022 GO:0043611 isoprene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043611 2-methyl-1,3-butadiene metabolism|hemiterpene metabolic process|hemiterpene metabolism|isoprene metabolism|2-methyl-1,3-butadiene metabolic process The chemical reactions and pathways involving isoprene, C5H8. GO:0043614 multi-eIF complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043614 multifactor translation initiation factor (eIF) complex A multifactor complex composed of multiple translation initiation factors and the initiatior tRNAiMet, which is ready to bind to the small (40S) ribosome to form the 43S preinitiation complex. In S. cerevisiae, this complex is composed of eIF1, eIF2, eIF3, and eIF5. GO:0043613 isoprene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043613 2-methyl-1,3-butadiene catabolism|hemiterpene catabolism|hemiterpene catabolic process|2-methyl-1,3-butadiene catabolic process The chemical reactions and pathways resulting in the breakdown of isoprene, C5H8. GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043619 Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. CL:0019019 tracheobronchial smooth muscle cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0019019 smooth muscle cell of tracheobronchial tree A smooth muscle cell that is part of the tracheobronchial tree. GO:0102360 daphnetin 3-O-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102360 EC:2.4.1.91|MetaCyc:RXN-13452 Catalysis of the reaction: UDP-alpha-D-glucose(2-) + 7,8-dihydroxycoumarin <=> UDP(3-) + 3-O-beta-D-glucosyl-daphnetin + H+. CL:0019018 blood vessel smooth muscle cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0019018 smooth muscle cell of blood vessel A smooth muscle cell that is part of any blood vessel. CL:0019017 lymphatic vessel smooth muscle cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0019017 smooth muscle cell of lymphatic vessel A smooth muscle cell that is part of any lymphatic vessel. GO:0102362 esculetin 3-O-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102362 MetaCyc:RXN-13472 Catalysis of the reaction: esculetin + UDP-alpha-D-glucose <=> 3-O-beta-D-glucosyl-esculetin + UDP + H+. GO:0102361 esculetin 4-O-beta-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102361 EC:2.4.1.126|MetaCyc:RXN-13471 Catalysis of the reaction: esculetin + UDP-alpha-D-glucose <=> 4-O-beta-D-glucosyl-esculetin + UDP + H+. GO:0102363 isoscopoletin-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102363 MetaCyc:RXN-13475 Catalysis of the reaction: isoscopoletin + S-adenosyl-L-methionine <=> scoparone + S-adenosyl-L-homocysteine + H+. GO:0102366 7-beta-hydroxytaxusin 2-alpha-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102366 MetaCyc:RXN-13487 Catalysis of the reaction: 7-beta-hydroxytaxusin + NADPH + O2 + H+ = 2alpha, 7-beta-dihydroxytaxusin + NADP + H2O. GO:0102365 taxusin 2-alpha-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102365 MetaCyc:RXN-13486 Catalysis of the reaction: taxusin + NADPH + O2 + H+ = 2-alpha-hydroxytaxusin + NADP + H2O. GO:0043621 protein self-association biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0043621 protein self binding|protein self association|intramolecular protein binding Interacting selectively and non-covalently with a domain within the same polypeptide. GO:0102368 beta-amyrin 30-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102368 MetaCyc:RXN-13489 Catalysis of the reaction: beta-amyrin + NADPH + H+ + O2 <=> 30-hydroxy-beta-amyrin + NADP + H2O. GO:0102367 2-alpha-hydroxytaxusin 7-beta-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102367 MetaCyc:RXN-13488 Catalysis of the reaction: 2alpha-hydroxytaxusin + NADPH + O2 + H+ <=> 2alpha, 7beta-dihydroxytaxusin + NADP + H2O. GO:0043620 regulation of DNA-templated transcription in response to stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043620 regulation of DNA-dependent transcription in response to stress Modulation of the frequency, rate or extent of transcription from a DNA template as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). GO:0102369 11alpha-30-dihydroxy beta-amyrin dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102369 MetaCyc:RXN-13491 Catalysis of the reaction: 11alpha,30-dihydroxy-beta-amyrin + NADPH + O2 + H+ <=> 30-hydroxy-11-oxo-beta-amyrin + NADP + 2 H2O. OBO:GOCHE_35523 substance with bronchodilator agent role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_35523 GO:0043627 response to estrogen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043627 response to estrogen stimulus|response to oestrogen stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics. GO:0043626 PCNA complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043626 PCNA homotrimer|proliferating cell nuclear antigen complex|sliding clamp A protein complex composed of three identical PCNA monomers, each comprising two similar domains, which are joined in a head-to-tail arrangement to form a homotrimer. Forms a ring-like structure in solution, with a central hole sufficiently large to accommodate the double helix of DNA. Originally characterized as a DNA sliding clamp for replicative DNA polymerases and as an essential component of the replisome, and has also been shown to be involved in other processes including Okazaki fragment processing, DNA repair, translesion DNA synthesis, DNA methylation, chromatin remodeling and cell cycle regulation. GO:0043629 ncRNA polyadenylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043629 non-coding RNA polyadenylation The enzymatic addition of a sequence of adenylyl residues at the 3' end of a non-coding RNA (ncRNA) molecule. In eukaryotes, substrates include nuclear non-coding RNAs such as precursors and a variety of incorrectly processed forms of snRNAs, snoRNAs, rRNAs, and tRNAs, as well as discarded RNA fragments which have been removed from ncRNA primary transcripts. Polyadenylation of precursors is often linked to termination of transcription, but polyadenylation of RNAs targeted for degradation may also occur post-transcriptionally. This polyadenylation is important both for 3'-end processing to produce mature ncRNA species and also for targeting incorrectly processed or discarded RNA molecules for degradation. GO:0043628 ncRNA 3'-end processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043628 ncRNA 3' end processing Any process involved in forming the mature 3' end of a non-coding RNA molecule. GO:0043623 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043623 CHEBI:78033 methyl arachidonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78033 GO:0043622 cortical microtubule organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043622 cortical microtubule organisation|cortical microtubule organization and biogenesis|cortical microtubule cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cell cortex, i.e. just beneath the plasma membrane of a cell. GO:0043625 delta DNA polymerase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043625 delta-DNA polymerase complex A multimeric DNA polymerase enzyme complex which differs in composition amongst species; in humans it is a heterotetramer of four subunits of approximately 125, 50, 68 and 12kDa, while in S. cerevisiae, it has three different subunits which form a heterotrimer, and the active enzyme is a dimer of this heterotrimer. Functions in DNA replication, mismatch repair and excision repair. GO:0043624 cellular protein complex disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043624 The disaggregation of a protein complex into its constituent components, occurring at the level of an individual cell. Protein complexes may have other associated non-protein prosthetic groups, such as nucleic acids, metal ions or carbohydrate groups. CHEBI:78035 12(S)-HPETE methyl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78035 CHEBI:78034 12(R)-HPETE methyl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78034 GO:0102371 betulin dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102371 MetaCyc:RXN-13498 Catalysis of the reaction: betulin + NADPH(4-) + H+ + O2 <=> betulinic aldehyde + NADP(3-) + 2 H2O. PR:000020966 polymeric immunoglobulin receptor proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000020966 PIGR/ClvPrd A polymeric immunoglobulin receptor that has been processed by proteolytic cleavage. PR:000019973 gastrin proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000019973 GAST/ClvPrd A gastrin that has been processed by proteolytic cleavage. GO:0102370 lupeol 28-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102370 MetaCyc:RXN-13497 Catalysis of the reaction: lupeol + NADPH(4-) + O2 + H+ <=> betulin + NADP(3-) + H2O. GO:0102373 uvaol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102373 MetaCyc:RXN-13501 Catalysis of the reaction: uvaol + NADPH + O2 + H+ <=> ursolic aldehyde + NADP + 2 H2O. GO:0102372 alpha-amyrin 28-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102372 MetaCyc:RXN-13500 Catalysis of the reaction: alpha-amyrin + NADPH(4-) + O2 + H+ <=> uvaol + NADP(3-) + H2O. GO:0102375 11-oxo-beta-amyrin 30-oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102375 RHEA:35499|MetaCyc:RXN-13506|EC:1.14.14.115 Catalysis of the reaction: 11-oxo-beta-amyrin + 3 NADPH + 3 O2 + 2 H+ <=> glycyrrhetinic acid + 3 NADP + 4 H2O. GO:0102374 ursolic aldehyde 28-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102374 MetaCyc:RXN-13502 Catalysis of the reaction: ursolic aldehyde + NADPH + O2 + H+ <=> ursolic acid + NADP + H2O. GO:0043630 ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043630 ncRNA polyadenylation during polyadenylation-dependent ncRNA catabolic process|ncRNA polyadenylation involved in poly(A)-dependent ncRNA catabolic process The enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end of a non-coding RNA, occurring as part of the process of polyadenylation-dependent non-coding RNA catabolism. GO:0102377 steviol 13-O glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102377 MetaCyc:RXN-13511 Catalysis of the reaction: steviol + UDP-alpha-D-glucose = steviolmonoside + UDP + H+. GO:0102376 lupeol 28-oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102376 MetaCyc:RXN-13507 Catalysis of the reaction: lupeol + 3 NADPH + 3 O2 + 3 H+ <=> betulinic acid + 3 NADP + 4 H2O. GO:0043632 modification-dependent macromolecule catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043632 The chemical reactions and pathways resulting in the breakdown of a macromolecule, initiated by covalent modification of the target molecule. GO:0102379 steviolbioside glucosyltransferase activity (stevioside forming) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102379 MetaCyc:RXN-13514 Catalysis of the reaction: steviolbioside + UDP-alpha-D-glucose = stevioside + UDP + H+. GO:0102378 steviolmonoside glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102378 MetaCyc:RXN-13512 Catalysis of the reaction: steviolmonoside + UDP-alpha-D-glucose = rubusoside + UDP + H+. GO:0043631 RNA polyadenylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043631 The enzymatic addition of a sequence of adenylyl residues at the 3' end of an RNA molecule. CL:0019003 tracheobronchial goblet cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0019003 goblet cell of tracheobronchial tree Any goblet cell that is part of the tracheobronchial epithelium. CL:0019002 tracheobronchial chondrocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0019002 chondrocyte of tracheobronchial tree Any chondrocyte that is part of the tracheobronchial tree. GO:0043638 puromycin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043638 The chemical reactions and pathways resulting in the formation of puromycin, an aminonucleoside antibiotic that is a potent inhibitor of translation; produced by the bacterium Streptomyces alboniger. CHEBI:78040 13(S)-HPODE methyl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78040 GO:0043637 puromycin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043637 puromycin metabolism The chemical reactions and pathways involving puromycin, 3'-deoxy-N,N-dimethyl-3'-(O-methyl-L-tyrosinamido)adenosine, an aminonucleoside antibiotic that is a potent inhibitor of translation; produced by the bacterium Streptomyces alboniger. GO:0043639 benzoate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043639 benzoate catabolism|benzoate degradation|benzoate breakdown The chemical reactions and pathways resulting in the breakdown of benzoate, the anion of benzoic acid (benzenecarboxylic acid), a fungistatic compound widely used as a food preservative; it is conjugated to glycine in the liver and excreted as hippuric acid. GO:0043634 polyadenylation-dependent ncRNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043634 poly(A)-dependent ncRNA catabolic process The chemical reactions and pathways resulting in the breakdown of a noncoding RNA (ncRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target ncRNA. CHEBI:78044 1-oleoyl-2-acetyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78044 CHEBI:78043 (5Z,8Z,11Z)-icosatrienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78043 GO:0043633 polyadenylation-dependent RNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043633 polyadenylation-dependent RNA catabolic process The chemical reactions and pathways resulting in the breakdown of an RNA molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3'-end of the target RNA. GO:0043636 bisphenol A catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043636 bisphenol-A catabolic process|bisphenol-A catabolism The chemical reactions and pathways resulting in the breakdown of bisphenol A, 4,4'-(propane-2,2-diyl)diphenol, a synthetic, aromatic organic compound used as a monomer in the manufacture of polycarbonate plastic and in the manufacture of epoxy resins. GO:0043635 methylnaphthalene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043635 1-methylnaphthalene catabolism|2-methylnaphthalene catabolism|2-methylnaphthalene catabolic process|1-methylnaphthalene catabolic process|1-MN catabolic process|2-MN catabolic process|2-MN catabolism|1-MN catabolism The chemical reactions and pathways resulting in the breakdown of methylnaphthalene, an organic compound, C10H7CH3, obtained from coal tar. CHEBI:78048 14(S)-HPDHE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78048 CHEBI:78047 12(S)-HPE(8,10,14)TrE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78047 CHEBI:78046 12(S)-HPE(5,8,10)TrE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78046 CHEBI:20702 2-aminopurines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20702 CHEBI:78045 2-acetyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78045 CHEBI:20706 6-aminopurines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20706 CHEBI:78049 octadecenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78049 GO:0102380 steviolbioside glucosyltransferase activity (rebaudioside B forming) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102380 MetaCyc:RXN-13516 Catalysis of the reaction: steviolbioside + UDP-alpha-D-glucose = rebaudioside B + UDP + H+. GO:0102382 rebaudioside B glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102382 MetaCyc:RXN-13518 Catalysis of the reaction: rebaudioside B + UDP-alpha-D-glucose <=> rebaudioside A + UDP + H+. GO:0102381 stevioside glucosyltransferase activity (rebaudioside A forming) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102381 MetaCyc:RXN-13517 Catalysis of the reaction: stevioside + UDP-alpha-D-glucose = rebaudioside A + UDP + H+. GO:0102384 19-O-beta-glucopyranosyl-steviol glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102384 MetaCyc:RXN-13521 Catalysis of the reaction: 19-O-beta-glucopyranosyl-steviol + UDP-alpha-D-glucose <=> rubusoside + UDP + H+. GO:0102383 steviol 19-O glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102383 MetaCyc:RXN-13520 Catalysis of the reaction: steviol + UDP-alpha-D-glucose <=> 19-O-beta-glucopyranosyl-steviol + UDP + H+. GO:0102386 phenylacetaldehyde reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102386 MetaCyc:RXN-13536 Catalysis of the reaction: 2-phenylethanol + NADP = phenylacetaldehyde + NADPH + H+. GO:0102385 patchoulol synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102385 MetaCyc:RXN-13522 Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> seychellene + diphosphoric acid. GO:0043641 novobiocin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043641 Wikipedia:Novobiocin novobiocin metabolism The chemical reactions and pathways involving novobiocin, a coumarin antibiotic produced by the bacterium Gyrasestreptomyces spheroides, that acts by inhibiting DNA gyrase. GO:0102388 UDP-N,N'-diacetylbacillosamine 2-epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102388 RHEA:34491|EC:3.2.1.184|MetaCyc:RXN-13574 Catalysis of the reaction: UDP-N,N'-diacetylbacillosamine + H2O <=> 2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose + UDP + H+. GO:0102387 2-phenylethanol acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102387 EC:2.3.1.224|MetaCyc:RXN-13542 Catalysis of the reaction: 2-phenylethanol + acetyl-CoA = phenethyl acetate + coenzyme A. GO:0043640 benzoate catabolic process via hydroxylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043640 MetaCyc:PWY-2503 benzoate degradation via hydroxylation|benzoate breakdown via hydroxylation The chemical reactions and pathways resulting in the breakdown of benzoate, by its hydroxylation to cis-1,2-dihydroxybenzoate followed by dehydrogenation to catechol. GO:0043643 tetracycline metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043643 tetracyclin metabolism|tetracycline metabolism|tetracyclin metabolic process The chemical reactions and pathways involving tetracycline, (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, a broad-spectrum antibiotic produced by streptomyces bacteria that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles). GO:0043642 novobiocin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043642 Wikipedia:Novobiocin The chemical reactions and pathways resulting in the formation of novobiocin, a coumarin antibiotic produced by the bacterium Gyrasestreptomyces spheroides, that acts by inhibiting DNA gyrase. GO:0102389 polyprenol reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102389 MetaCyc:RXN-13604|EC:1.3.1.94|RHEA:34279 Catalysis of the reaction: NADP + a ditrans,polycis-dolichol = NADPH + H+ + a di-trans, poly-cis-polyprenol. GO:0043649 dicarboxylic acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043649 dicarboxylic acid breakdown|dicarboxylate catabolism|dicarboxylate catabolic process|dicarboxylic acid catabolism|dicarboxylic acid degradation The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups. CHEBI:78051 hexacosapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78051 CHEBI:78050 octadecatetraenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78050 GO:0043648 dicarboxylic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043648 dicarboxylic acid metabolism|dicarboxylate metabolism|dicarboxylate metabolic process The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two carboxyl (COOH) groups or anions (COO-). CHEBI:78055 hexacosenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78055 GO:0043645 cephalosporin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043645 cephalosporin metabolism The chemical reactions and pathways involving a cephalosporin, any of large class of tetracyclic triterpene broad-spectrum antibiotics similar both chemically and in their mode of action to penicillin, first isolated from the culture filtrates of mediterranean fungus acremonium (cephalosporium acremonium), and effective against gram-positive bacteria. CHEBI:78054 hexacosatetraenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78054 GO:0043644 tetracycline biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043644 tetracyclin biosynthetic process|tetracyclin biosynthesis The chemical reactions and pathways resulting in the formation of tetracycline, (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, a broad-spectrum antibiotic produced by streptomyces bacteria that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles). GO:0043647 inositol phosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043647 myo-inositol phosphate metabolism|myo-inositol phosphate metabolic process|inositol phosphate metabolism The chemical reactions and pathways involving inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached. CHEBI:78053 docosapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78053 CHEBI:78052 tetracosapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78052 GO:0043646 cephalosporin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043646 The chemical reactions and pathways resulting in the formation of a cephalosporin, any of large class of tetracyclic triterpene broad-spectrum antibiotics similar both chemically and in their mode of action to penicillin, first isolated from the culture filtrates of mediterranean fungus acremonium (cephalosporium acremonium), and effective against gram-positive bacteria. CHEBI:19733 (2,2,3-trimethyl-5-oxocyclopent-3-en-1-yl)acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_19733 CHEBI:78059 food additive carrier biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78059 CHEBI:20710 3-dehydro-6-deoxoteasterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_20710 CHEBI:78057 hexacosahexaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78057 CHEBI:78056 tetracosahexaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78056 CHEBI:20717 6-deoxotyphasterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_20717 GO:0102311 8-hydroxygeraniol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102311 EC:1.1.1.324|MetaCyc:RXN-12961|RHEA:32659 Catalysis of the reaction: (6E)-8-hydroxygeraniol + 2 NADP <=> (6E)-8-oxogeranial + 2 NADPH + 2 H+. GO:0043652 engulfment of apoptotic cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043652 engulfment of cell corpse|engulfment of apoptotic cell corpse The removal of the apoptotic cell by phagocytosis, by a neighboring cell or by a phagocyte. GO:0043651 linoleic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043651 Wikipedia:Linoleic_acid linoleic acid metabolism The chemical reactions and pathways involving linoleic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2. GO:0102310 dTDP-(2R,6S)-6-hydroxy-2-methyl-3-oxo-3,6-dihydro-2H-pyran-4-olate 3-ketoreductase (dTDP-4-dehydro-2,6-dideoxy-alpha-D-allose-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102310 MetaCyc:RXN-12940 Catalysis of the reaction: dTDP-4-dehydro-2,6-dideoxy-alpha-D-allose + NAD(P) <=> dTDP-(2R,6S)-6-hydroxy-2-methyl-3-oxo-3,6-dihydro-2H-pyran-4-olate + 2 H+ + NAD(P)H. GO:0043654 recognition of apoptotic cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043654 recognition of apoptotic cell corpse|recognition of cell corpse|detection of apoptotic cell corpse|detection of apoptotic cell|detection of cell corpse The process in which a cell interprets signals (in the form of specific proteins and lipids) on the surface of a dying cell which it will engulf and remove by phagocytosis. GO:0102313 1,8-cineole synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102313 MetaCyc:RXN-12980|RHEA:32543|EC:4.2.3.108 Catalysis of the reaction: geranyl diphosphate(3-) + H2O <=> 1,8-cineole + diphosphoric acid. GO:0043653 mitochondrial fragmentation involved in apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043653 mitochondrial fission during apoptosis|mitochondrial fragmentation involved in apoptosis The change in the morphology of the mitochondria in an apoptotic cell from a highly branched network to a fragmented vesicular form. GO:0102312 4-coumaroyl 2'-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102312 MetaCyc:RXN-12963|RHEA:57868 Catalysis of the reaction: 4-coumaryl-CoA + 2-oxoglutarate + O2 <=> 2,4-dihydroxycinnamoyl-CoA + succinate + carbon dioxide. GO:0102315 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0102315 GO:0043650 dicarboxylic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043650 dicarboxylic acid biosynthesis|dicarboxylic acid anabolism|dicarboxylate biosynthesis|dicarboxylate biosynthetic process|dicarboxylic acid synthesis|dicarboxylic acid formation The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups. GO:0102317 4-methylaminobutyrate oxidase (demethylating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102317 MetaCyc:RXN-13067|RHEA:33907|EC:1.5.3.19 Catalysis of the reaction: 4-(methylamino)butyric acid + O2 + H2O <=> gamma-aminobutyric acid + formaldehyde + hydrogen peroxide. GO:0102316 L-dopa oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102316 MetaCyc:RXN-13061 Catalysis of the reaction: L-dopa + 0.5 O2 = L-dopaquinone + H2O. GO:0102319 2-deoxystreptamine N-acetyl-D-glucosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102319 EC:2.4.1.283|MetaCyc:RXN-13122|RHEA:33947 Catalysis of the reaction: 2-deoxystreptamine(2+) + UDP-N-acetyl-alpha-D-glucosamine <=> H+ + 2'-N-acetylparomamine(2+) + UDP(3-). CHEBI:78062 octacosatetraenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78062 GO:0102318 2-deoxystreptamine glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102318 RHEA:34063|EC:2.4.1.284|MetaCyc:RXN-13121 Catalysis of the reaction: 2-deoxystreptamine + UDP-alpha-D-glucose <=> 2'-deamino-2'-hydroxyparomamine + UDP(3-) + H+. CHEBI:78061 tetracosatetraenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78061 GO:0043659 symbiosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043659 A double-enveloped cell compartment, composed of an endosymbiont with its plasmalemma (as inner envelope) and a non-endosymbiotic outer envelope (the perisymbiontic membrane). PR:000005388 glycoprotein hormones alpha chain biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000005388 TSH-alpha|choriogonadotropin alpha chain|CG-alpha|luteinizing hormone alpha chain|LSH-alpha|lutropin alpha chain|FSH-alpha|thyroid-stimulating hormone alpha chain|anterior pituitary glycoprotein hormones common subunit alpha|follicle-stimulating hormone alpha chain|thyrotropin alpha chain|chorionic gonadotrophin subunit alpha|follitropin alpha chain|CGA A protein that is a translation product of the human CGA gene or a 1:1 ortholog thereof. CHEBI:78060 docosahexaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78060 GO:0043656 host intracellular region biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043656 intracellular region of host|host intracellular That space within the plasma membrane of a host cell. GO:0043655 host extracellular space biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043655 extracellular space of host|host extracellular space The space within a host but external to the plasma membrane of host cells, e.g. within host bloodstream. GO:0043658 host symbiosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043658 A double-enveloped cell compartment, composed of the endosymbiont with its plasmalemma (as inner envelope) and an outer envelope (the perisymbiontic membrane) derived from the host cell. GO:0043657 host cell biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043657 A cell within a host organism. Includes the host plasma membrane and any external encapsulating structures such as the host cell wall and cell envelope. CHEBI:78063 octacosapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78063 CHEBI:78069 docosatetraenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78069 CHEBI:78068 tetracosenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78068 GO:0102320 1,8-cineole 2-exo-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102320 RHEA:32895|EC:1.14.14.56|MetaCyc:RXN-13133 Catalysis of the reaction: 1,8-cineole + NADPH + H+ + O2 <=> 2-exo-hydroxy-1,8-cineole + NADP + H2O. GO:0043663 host bacteroid-containing symbiosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043663 A symbiosome containing any of various structurally modified bacteria, such as those occurring on the root nodules of leguminous plants, of a host cell. GO:0102322 2-propylphenol monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102322 MetaCyc:RXN-13151|RHEA:63524 Catalysis of the reaction: 2-propylphenol + O2 + NADH + H+ = 3-propylcatechol + H2O + NAD. GO:0102321 2,2'-hydroxybiphenyl monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102321 MetaCyc:MONOMER-17239|EC:1.14.13.44 Catalysis of the reaction: biphenyl-2,2'-diol + O2 + NADH + H+ <=> biphenyl-2,2',3-triol + H2O + NAD. GO:0043662 peribacteroid fluid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043662 The soluble material inside the peribacteroid membrane, but outside of the bacteroid, within a bacteroid-containing symbiosome. GO:0043665 host peribacteroid fluid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043665 The soluble material inside the peribacteroid membrane, but outside of the bacteroid, within a bacteroid-containing symbiosome of a host cell. GO:0102324 2-hydroxy-6-oxo-nona-2,4-dienoate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102324 MetaCyc:RXN-13157 Catalysis of the reaction: 2-hydroxy-6-oxo-nona-2,4-dienoate + H2O = butyrate + 2-oxopent-4-enoate + H+. GO:0102323 2-isopropylphenol monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102323 RHEA:63520|MetaCyc:RXN-13152 Catalysis of the reaction: 2-isopropylphenol + O2 + NADH + H+ = 3-isopropylcatechol + H2O + NAD. GO:0043664 host peribacteroid membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043664 A host-derived membrane that surrounds one or more bacteroids (such as nitrogen-fixing bacteroids within legume root nodule cells). GO:0102326 2-hydroxy-6-oxo-6-(2,3-dihydroxyphenyl)-hexa-2,4-dienoate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102326 MetaCyc:RXN-13171 Catalysis of the reaction: 2-hydroxy-6-oxo-6-(2,3-dihydroxyphenyl)-hexa-2,4-dienoate + H2O <=> 2,3-dihydroxybenzoate + 2-oxopent-4-enoate + H+. CHEBI:78080 triacontahexaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78080 GO:0102325 2,2',3-trihydroxybiphenyl monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102325 MetaCyc:RXN-13169|RHEA:63516 Catalysis of the reaction: biphenyl-2,2',3-triol + O2 + NADH + H+ <=> 2,2',3,3'-tetrahydroxybiphenyl + NAD + H2O. GO:0043661 peribacteroid membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043661 A membrane that surrounds one or more bacteroids (such as nitrogen-fixing bacteroids within legume root nodule cells). GO:0102328 3-oxoacid decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102328 MetaCyc:RXN-13248 Catalysis of the reaction: H+ + a 3-oxoacid = carbon dioxide + a methylketone. GO:0043660 bacteroid-containing symbiosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043660 A symbiosome containing any of various structurally modified bacteria, such as those occurring on the root nodules of leguminous plants. GO:0102327 3-oxoacyl-CoA hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102327 MetaCyc:RXN-13247 Catalysis of the reaction: H2O + a 3-oxoacyl-CoA = H+ + coenzyme A + a 3-oxoacid. CHEBI:78073 icosadienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78073 CHEBI:78072 icosatrienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78072 GO:0102329 hentriaconta-3,6,9,12,19,22,25,28-octaene-16-one-15-oyl-CoA reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102329 MetaCyc:RXN-13251 Catalysis of the reaction: 16-hydroxy-hentriaconta-3,6,9,12,19,22,25,28-octaene-15-oyl-CoA + NADP <=> hentriaconta-3,6,9,12,19,22,25,28-octaene-16-one-15-oyl-CoA + NADPH + H+. CHEBI:78070 10(R)-HPO(6,8,12)TrE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78070 GO:0043667 pollen wall biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043667 microspore wall The wall surrounding a mature pollen grain; a multilayered structure consisting of a pectocellulosic intine surrounded by a sporopollenin-based exine, which itself contains two layers, the inner nexine and the outer sexine. CHEBI:78076 docosenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78076 GO:0043666 regulation of phosphoprotein phosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043666 regulation of protein phosphatase type 2A activity|regulation of protein phosphatase type 2B activity|regulation of protein phosphatase 3 activity|regulation of calcineurin activity|regulation of protein phosphatase type 2 activity Any process that modulates the frequency, rate or extent of phosphoprotein phosphatase activity, the catalysis of the hydrolysis of phosphate from a phosphoprotein. CHEBI:78075 icosenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78075 GO:0043669 ectexine biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043669 The outer part of the exine, which stains positively with basic fuchsin in optical microscopy and has higher electron density in conventionally prepared TEM sections. GO:0043668 exine biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043668 The outer layer of the pollen grain wall which is composed primarily of sporopollenin. CHEBI:78079 triacontatetraenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78079 CHEBI:78078 12-HPEPE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78078 GO:0102331 heptadecanoyl-[acp] elongase/decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102331 MetaCyc:RXN-13259 Catalysis of the reaction: malonyl-CoA + 3 H+ + a heptodecanoyl-[acp] = octadec-1-ene + 2 carbon dioxide + coenzyme A + a holo-[acyl-carrier protein]. GO:0102330 palmitoyl-[acp] elongase/decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102330 MetaCyc:RXN-13258 Catalysis of the reaction: malonyl-CoA + a palmitoyl-[acp] = 1-heptadecene + 2 carbon dioxide + coenzyme A + a holo-[acyl-carrier protein]. GO:0102333 stearoyl-[acp] elongase/decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102333 MetaCyc:RXN-13261 Catalysis of the reaction: malonyl-CoA + 3 H+ + a stearoyl-[acp] = nonadec-1-ene + 2 carbon dioxide + coenzyme A + a holo-[acyl-carrier protein]. GO:0043674 columella biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043674 sexine 1 A rod-like element of the sexine and ectexine, supporting either the tectum (the layer of sexine which forms a roof over the columella), or supporting a caput (an architectural element on top of a columella). GO:0043673 sexine biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043673 The outer, sculptured layer of the exine, which lies above the nexine. GO:0102332 fatty-acyl-[acp] elongase/decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102332 MetaCyc:RXN-13260 Catalysis of the reaction: malonyl-CoA + H+ + a long-chain acyl-[acp] + a reduced electron acceptor = 2 carbon dioxide + coenzyme A + a terminal olefin + a holo-[acyl-carrier protein] + an oxidized electron acceptor. GO:0102335 N,N'-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1,3-N-acetylgalactosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102335 EC:2.4.1.290|MetaCyc:RXN-13274|RHEA:34511 Catalysis of the reaction: N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tri-trans,hepta-cis-undecaprenol + UDP-N-acetyl-D-galactosamine <=> N-acetyl-D-galactosaminyl-alpha-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tri-trans,hepta-cis-undecaprenol + UDP + H+. GO:0043676 tectum biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043676 sexine 2 The layer of sexine which forms a roof over the columella, granules or other infratectal elements. GO:0102334 N,N'-diacetylbacilliosaminyl-1-phosphate transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102334 MetaCyc:RXN-13269|RHEA:34515|EC:2.7.8.36 Catalysis of the reaction: ditrans,polycis-undecaprenyl phosphate + UDP-N,N'-diacetylbacillosamine <=> N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tri-trans,hepta-cis-undecaprenol + UMP. GO:0043675 sculpture element biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043675 The third layer of the sexine. GO:0102337 3-oxo-cerotoyl-CoA synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102337 EC:2.3.1.199|MetaCyc:RXN-13296 Catalysis of the reaction: tetracosanoyl-CoA(4-) + malonyl-CoA(5-) + H+ <=> 3-oxohexacosanoyl-CoA + carbon dioxide + coenzyme A. GO:0043670 foot layer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043670 nexine 1 The inner layer of the ectexine. CHEBI:78091 hexatriacontapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78091 GO:0102336 3-oxo-arachidoyl-CoA synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102336 EC:2.3.1.199|MetaCyc:RXN-13294 Catalysis of the reaction: stearoyl-CoA(4-) + malonyl-CoA(5-) + H+ <=> 3-oxoicosanoyl-CoA. + carbon dioxide + coenzyme A. CHEBI:78090 1,2-dipalmitoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78090 GO:0043672 nexine biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043672 The inner, non-sculptured part of the exine which lies below the sexine. GO:0102339 3-oxo-arachidoyl-CoA reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102339 EC:1.1.1.330|MetaCyc:RXN-13298 Catalysis of the reaction: (R)-3-hydroxyicosanoyl-CoA(4-) + NADP(3-) <=> 3-oxoicosanoyl-CoA + NADPH + H+. GO:0102338 3-oxo-lignoceronyl-CoA synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102338 EC:2.3.1.199|MetaCyc:RXN-13297 Catalysis of the reaction: behenoyl-CoA(4-) + malonyl-CoA(5-) + H+ <=> 3-oxotetracosanoyl-CoA. + carbon dioxide + coenzyme A. GO:0043671 endexine biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043671 The inner part of the exine, which stains. CHEBI:78084 hepoxilin B3(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78084 CHEBI:78083 dotriacontahexaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78083 CHEBI:78082 dotriacontapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78082 CHEBI:78081 dotriacontatetraenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78081 GO:0043678 intine biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043678 The innermost of the major layers of the pollen grain wall which underlies the exine and borders the cytoplasm. CHEBI:78088 tetratriacontahexaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78088 GO:0043677 obsolete germination pore biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043677 Wikipedia:Germ_pore germ pore OBSOLETE. A small pore in the outer wall of a mycelial spore through which the germ tube exits upon germination. It can be apical or eccentric in its location. CHEBI:78087 tetratriacontapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78087 CHEBI:19702 N(2)-methylguanosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_19702 CHEBI:78086 tetratriacontatetraenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78086 GO:0043679 axon terminus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043679 NIF_Subcellular:nlx_subcell_20090512 axon terminal specialization|nerve ending|axon terminal Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal button is a specialized region of it. CHEBI:78085 N-hexadecanoylphosphatidylethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78085 CHEBI:78089 hexatriacontatetraenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78089 GO:0102340 3-oxo-behenoyl-CoA reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102340 EC:1.1.1.330|MetaCyc:RXN-13299 Catalysis of the reaction: (R)-3-hydroxybehenoyl-CoA(4-) + NADP(3-) <=> 3-oxodocosanoyl-CoA + NADPH + H+. GO:0102342 3-oxo-cerotoyl-CoA reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102342 EC:1.1.1.330|MetaCyc:RXN-13301 Catalysis of the reaction: (R)-3-hydroxycerotoyl-CoA + NADP <=> 3-oxohexacosanoyl-CoA + NADPH + H+. GO:0102341 3-oxo-lignoceroyl-CoA reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102341 EC:1.1.1.330|MetaCyc:RXN-13300 Catalysis of the reaction: (R)-3-hydroxylignoceroyl-CoA + NADP <=> 3-oxotetracosanoyl-CoA + NADPH + H+. GO:0102344 3-hydroxy-behenoyl-CoA dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102344 EC:4.2.1.134|MetaCyc:RXN-13303 Catalysis of the reaction: (R)-3-hydroxybehenoyl-CoA <=> trans-2-docosenoyl-CoA + H2O. GO:0043685 conversion of glutamyl-tRNA to glutaminyl-tRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043685 The modification process that results in the conversion of glutamate charged on a tRNA(Gln) to glutaminyl-tRNA. GO:0043684 type IV secretion system complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043684 type IV protein secretion system complex|T4SS complex A complex of proteins related to those involved in bacterial DNA conjugative transfer, that permits the transfer of DNA or proteins into the extracellular milieu or directly into host cells. In general the type IV complex forms a multisubunit cell-envelope-spanning structure composed of a secretion channel and often a pilus or other surface filament or protein(s). GO:0102343 3-hydroxy-arachidoyl-CoA dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102343 EC:4.2.1.134|MetaCyc:RXN-13302 Catalysis of the reaction: (R)-3-hydroxyicosanoyl-CoA <=> trans-2-icosenoyl-CoA + H2O. GO:0043687 post-translational protein modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043687 Wikipedia:Posttranslational_modification post-translational modification|post-translational amino acid modification|PTM|posttranslational modification|posttranslational protein modification|posttranslational amino acid modification The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome. GO:0102346 3-hydroxy-cerotoyl-CoA dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102346 MetaCyc:RXN-13305 Catalysis of the reaction: (R)-3-hydroxycerotoyl-CoA(4-) <=> trans-2-hexacosenoyl-CoA(4-) + H2O. GO:0043686 co-translational protein modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043686 cotranslational amino acid modification|cotranslational modification|cotranslational protein modification|co-translational modification|co-translational amino acid modification The process of covalently altering one or more amino acids in a protein after translation has begun but before the protein has been released from the ribosome. GO:0102345 3-hydroxy-lignoceroyl-CoA dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102345 EC:4.2.1.134|MetaCyc:RXN-13304 Catalysis of the reaction: (R)-3-hydroxylignoceroyl-CoA(4-) <=> trans-2-tetracosenoyl-CoA + H2O. GO:0102348 trans-docosan-2-enoyl-CoA reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102348 MetaCyc:RXN-13307 Catalysis of the reaction: behenoyl-CoA + NADP <=> trans-2-docosenoyl-CoA + NADPH + H+. GO:0043681 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043681 GO:0043680 filiform apparatus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043680 A complex of cell wall invaginations in a synergid cell, similar to those in transfer cells. GO:0102347 trans-arachidon-2-enoyl-CoA reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102347 MetaCyc:RXN-13306 Catalysis of the reaction: icosanoyl-CoA(4-) + NADP(3-) <=> trans-2-icosenoyl-CoA(4-) + NADPH(4-) + H+. GO:0043683 type IV pilus biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043683 type IV fimbrium biogenesis|type IV pilus biosynthesis|type IV fimbriae assembly|TFP biogenesis|type IV fimbria assembly|type 4 pilus biogenesis|type IV fimbriae biogenesis|type IV fimbrial assembly|type IV fimbria biogenesis|type IV fimbrial biogenesis|type IV fimbrium assembly A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a type IV pilus. A type IV pilus is composed of a pilus fiber and approximately ten proteins at its base; type IV pili play a role in cell motility, adherence to substrates, and aggregation. GO:0043682 P-type divalent copper transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043682 Reactome:R-HSA-936895|Reactome:R-HSA-936802|Reactome:R-HSA-3697838|MetaCyc:3.6.3.4-RXN|EC:7.2.2.9|Reactome:R-HSA-6803545|RHEA:10376 Cu2+-exporting ATPase activity|copper-translocating P-type ATPase activity|copper-transporting ATPase activity|copper-exporting ATPase activity|copper exporting ATPase activity|Cu(2+)-exporting ATPase activity|copper transmembrane transporter activity, phosphorylative mechanism Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cu2+(in) -> ADP + phosphate + Cu2+(out). GO:0102349 trans-lignocero-2-enoyl-CoA reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102349 MetaCyc:RXN-13308 Catalysis of the reaction: tetracosanoyl-CoA + NADP <=> trans-2-tetracosenoyl-CoA + NADPH + H+. CHEBI:78095 hexadecenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78095 CHEBI:78094 octatriacontapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78094 CHEBI:78093 octatriacontatetraenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78093 CHEBI:78092 hexatriacontahexaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78092 GO:0043689 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043689 CHEBI:78099 trioxilin B3(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78099 GO:0043688 conversion of aspartyl-tRNA to asparaginyl-tRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043688 The modification process that results in the conversion of aspartate charged on a tRNA(Asn) to asparaginyl-tRNA. CHEBI:78098 1-palmitylglycerone 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78098 CHEBI:78097 N-palmitoyl-1,2-dioleoyl-sn-glycero-3-phosphoethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78097 CHEBI:78096 hexadecadienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78096 CHEBI:20680 6,7-dihydrobiopterin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_20680 CHEBI:29019 nonanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29019 CHEBI:68623 UDP-N-acetyl-alpha-D-mannosamine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68623 CHEBI:29014 cordycepin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29014 CHEBI:29017 1-acyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29017 CHEBI:68625 valerena-4,7(11)-diene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68625 CHEBI:68624 cis-abienol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68624 CHEBI:29016 arginine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29016 CHEBI:29010 2'-aminobiphenyl-2,3-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29010 CHEBI:29013 fusidic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29013 PR:000019919 fibronectin proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000019919 FN1/ClvPrd A fibronectin that has been processed by proteolytic cleavage. UBERON:0005472 right vitelline vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005472 A vitelline vein that is in the right side of a multicellular organism. UBERON:0005470 right umbilical artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005470 embryonic right umbilical artery CHEBI:30001 D-selenocysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30001 UBERON:0005478 sulcus limitans of neural tube biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005478 sulcus limitans|neural tube lateral wall sulcus limitans A longitudinal groove in the neural tube wall that divides the neural tube into dorsal (alar) and ventral (basal) halves (dorsal receives input from sensory neurons, ventral effects motor functions); stretches from the mesencephalon caudad[TMD]. UBERON:0005476 spinal nerve trunk biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005476 spinal nerve (trunk)|trunk of spinal nerve|spinal neural trunk trunk part of spinal nerve, where dorsal and ventral roots meet to form the spinal nerve, before branching off to dorsal and ventral rami. CHEBI:19680 2-methylacetoacetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_19680 CHEBI:30018 D-proline residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30018 CHEBI:29028 glucobrassicin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29028 CHEBI:68636 p-hydroxyphenylbut-3-ene-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68636 CHEBI:44642 2'-O-methyluridine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_44642 CHEBI:29021 hexane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29021 CHEBI:29024 4-methyl-3-oxopentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29024 UBERON:0005463 subcapsular sinus of lymph node biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005463 marginal sinus|marginal sinus of lymph node|subcapsular sinus|lymph node subcortical sinus|lymph sinus|lymph path A space between the capsule and the cortex which allows the free movement of lymphatic fluid and so contains a sparsity of lymphocytes. It is continuous with the similar lymph sinuses that flank the trabeculae. CHEBI:29031 phosphinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29031 UBERON:0005461 levator scapulae muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005461 levator scapulæ|levator scapula|musculus levator scapulae|levator scapulae|levator scapulae muscle An axial muscle that originates in the cervical vertebraae inserts on the scapula. UBERON:0005460 left vitelline vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005460 A vitelline vein that is in the left side of a multicellular organism. CHEBI:30014 D-threonine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30014 CHEBI:30013 L-threonine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30013 UBERON:0005469 right thymus lobe biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005469 right thymic lobe|right lobe of thymus A thymus lobe that is in the right side of a thymus. CHEBI:30011 L-glutamine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30011 CHEBI:19672 4-oxohex-2-enedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19672 CHEBI:20664 5beta-cholane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_20664 CHEBI:68645 2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68645 UBERON:6057001 anterior-posterior subdivision of organism biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_6057001 UBERON:0005452 hepatic cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005452 liver cell plate|hepatic plate|hepatic lamina|hepatic laminae|lamina hepatica A three-dimensional arrangement formed by plates of hepatocytes, usually one cell thick, that radiates from the center of the liver lobule; hepatic laminae are highly branched, irregular structures bordered by endothelial lined vascular spaces called hepatic sinusoids. UBERON:0005451 segment of manus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005451 regio manus|segment of hand|subdivision of hand|hand subdivision|hand region A segment of autopod that is part of a manus. CHEBI:44639 tert-butylamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_44639 CHEBI:68649 pentalenate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68649 CHEBI:44638 2'-O-methylguanosine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_44638 UBERON:0005458 left umbilical artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005458 embryonic left umbilical artery UBERON:0005457 left thymus lobe biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005457 left lobe of thymus|left thymic lobe A thymus lobe that is in the left side of a thymus. UBERON:0005456 jugular foramen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005456 Posterior lacerate foramen|foramen jugulare The jugular foramen is a large aperture in the base of the skull. It is located behind the carotid canal and is formed in front by the petrous portion of the temporal, and behind by the occipital; it is generally larger on the right than on the left side CHEBI:20670 5beta-estrane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_20670 CHEBI:68650 1-deoxypentalenate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68650 CHEBI:20674 5beta-pregnane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_20674 CHEBI:29009 N(tele)-methylhistamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29009 CHEBI:29003 L-citramalic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29003 CHEBI:68655 Delta(6)-protoilludene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68655 CHEBI:68658 (+)-epi-alpha-bisabolol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68658 CHEBI:29006 N-acetyl-4-O-acetylneuraminate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29006 CHEBI:29005 cyclohexane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29005 CHEBI:68652 N-acetyl-alpha-D-galactosaminyl-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-tritrans,heptacis-undecaprenyl diphosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68652 CHEBI:68651 alpha-D-GalNAc-(1->4)-alpha-D-GalNAc-(1->3)-alpha-D-diNAcBac-tritrans,heptacis-undecaprenyl diphosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68651 CHEBI:68654 [alpha-D-GalNAc-(1->4)]2-[beta-D-Glc-(1->3)]-[alpha-D-GalNAc-(1->4)]2-alpha-D-GalNAc-(1->3)-alpha-D-diNAcBac-tritrans,heptacis-undecaprenyl diphosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68654 CHEBI:29002 (S)-propane-1,2-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29002 CHEBI:29001 (3R)-3-isopropenyl-6-oxoheptanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29001 CHEBI:68653 [alpha-D-GalNAc-(1->4)]4-alpha-D-GalNAc-(1->3)-alpha-D-diNAcBac-tritrans,heptacis-undecaprenyl diphosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68653 UBERON:0005446 foramen rotundum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005446 round foramen|foramen rotundum ossis sphenoidalis|foramen rotundum of the skull The foramen rotundum is a circular hole in the sphenoid bone that connects the middle cranial fossa and the pterygopalatine fossa. UBERON:0005445 segment of pes biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005445 segment of foot|subdivision of foot|foot subdivision|foot region|regio pedis A segment of autopod that is part of a pes. GO:0102391 decanoate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102391 RHEA:33627|MetaCyc:RXN-13614 Catalysis of the reaction: ATP + decanoate + CoA = AMP + diphosphate + decanoyl-CoA. GO:0102390 mycophenolic acid acyl-glucuronide esterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102390 EC:3.1.1.93|RHEA:34179|MetaCyc:RXN-13605 Catalysis of the reaction: mycophenolic acid O-acyl-glucuronide(1-) + H2O <=> mycophenolate + H+ + D-glucopyranuronate. GO:0102393 decanoyl-[acp] 2-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102393 MetaCyc:RXN-13624 Catalysis of the reaction: FAD + H+ + a decanoyl-HmqF protein <=> FADH2(2-) + a 2,3-dehydro-decanoyl-HmqF. GO:0102392 decanoate-[HmqF protein] ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102392 MetaCyc:RXN-13623 Catalysis of the reaction: decanoate + ATP(4-) + an HmqF protein <=> AMP(2-) + diphosphoric acid + a decanoyl-HmqF protein. GO:0102395 9-cis-beta-carotene 9',10'-cleavage oxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102395 RHEA:34399|EC:1.13.11.68|MetaCyc:RXN-13642 Catalysis of the reaction: 9-cis-beta-carotene + O2 <=> 9-cis-10'-apo-beta-carotenal + beta-ionone. GO:0102394 4-hydroxy-L-isoleucine dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102394 MetaCyc:RXN-13637 Catalysis of the reaction: (2S,3R,4S)-4-hydroxy-L-isoleucine + NAD <=> (2S,3R)-2-amino-3-methyl-4-ketopentanoate + NADH + H+. CHEBI:20640 5alpha-campestane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_20640 CHEBI:20642 5alpha-cholane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_20642 GO:0102396 9-cis-10'-apo-beta-carotenal cleavage oxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102396 RHEA:34403|EC:1.13.11.69|MetaCyc:RXN-13643 Catalysis of the reaction: 9-cis-10'-apo-beta-carotenal + 2 O2 <=> carlactone + (2E,4E,6E)-7-hydroxy-4-methylhepta-2,4,6-trienal. GO:0102399 dTDP-3-N-methylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102399 MetaCyc:RXN-13658 Catalysis of the reaction: S-adenosyl-L-methionine + dTDP-3-N-methylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose <=> S-adenosyl-L-homocysteine + dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose + H+. CHEBI:68667 (E)-2-epi-beta-caryophyllene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68667 CHEBI:68666 (-)-alpha-isocomene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68666 GO:0102398 dTDP-3-amino-4-oxo-2,3,6-trideoxy-alpha-D-glucose N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102398 MetaCyc:RXN-13657 Catalysis of the reaction: S-adenosyl-L-methionine + dTDP-3-amino-4-dehydro-2,3,6-trideoxy-alpha-D-glucose <=> S-adenosyl-L-homocysteine + dTDP-3-N-methylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose + H+. CHEBI:68669 N,N-diacetyllegionaminate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68669 PR:000019959 galanin proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000019959 GAL/ClvPrd A galanin that has been processed by proteolytic cleavage. CHEBI:68668 legionaminate(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68668 CHEBI:68665 pentalenic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68665 CHEBI:19641 2-hydroxyisobutyrate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_19641 CHEBI:68670 CMP-N,N-diacetyllegionaminate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68670 CHEBI:68672 N,N'-diacetyl-alpha-D-bacillosaminyl-tritrans,heptacis-undecaprenyl diphosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68672 CHEBI:68671 CMP-N-acyl-beta-neuraminate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68671 CHEBI:20652 5alpha-ergostane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_20652 CHEBI:68678 UDP-N-acetyl-alpha-D-mannosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68678 CHEBI:68677 dTDP-4-acetamido-4,6-dideoxy-alpha-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68677 CHEBI:68679 dTDP-6-deoxy-beta-L-talose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68679 CHEBI:68676 legionaminic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68676 CHEBI:68675 dTDP-4-acetamido-4,6-dideoxy-alpha-D-glucose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68675 CHEBI:20656 5alpha-pregnane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_20656 CHEBI:20659 5beta-androstane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_20659 CHEBI:68681 UDP-N-acetyl-6-(alpha-D-galactose-1-phospho)-alpha-D-glucosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68681 CHEBI:68683 CMP-N,N-diacetyllegionaminic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68683 CHEBI:68682 N,N-diacetyllegionaminic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68682 CHEBI:68689 5-phospho-alpha-D-ribose cyclic-1,2-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68689 CHEBI:68688 alpha-D-ribose 1,5-bisphosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68688 CHEBI:68685 alpha-D-ribose 1-methylphosphonate 5-triphosphate(4-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68685 CHEBI:68684 methylphosphonate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68684 CHEBI:68687 5-phosphonato-alpha-D-ribose cyclic-1,2-phosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68687 CHEBI:68686 alpha-D-ribose 1-methylphosphonate 5-phosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68686 UBERON:0005497 non-neural ectoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005497 ventral ectoderm|surface ectoderm|non neural ectoderm|epithelial ectoderm|epidermal ectoderm UBERON:0005496 neural tube lateral wall biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005496 lateral wall neural tube Portion of tissue on the side of the lumen of the neural tube. UBERON:0005491 glossopharyngeal neural crest biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005491 Cranial neural crest which gives rise to the glossopharyngeal ganglion. CHEBI:78004 food bulking agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78004 CHEBI:78003 food bleaching agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78003 CHEBI:78001 N-dodecanoylphytosphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78001 UBERON:0005499 rhombomere 1 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005499 r1 Hindbrain segment or neuromere 1. CHEBI:20629 5-phosphoribosyl-ATP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20629 UBERON:0005498 primitive heart tube biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005498 early primitive heart tube|primitive heart tube Multi-tissue structure that arises from the heart rudiment and will become the heart tube. CHEBI:19660 2-hydroxyoctadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19660 CL:0019031 intestine goblet cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0019031 intestinal goblet cell Goblet cells reside throughout the length of the small and large intestine and are responsible for the production and maintenance of the protective mucus blanket by synthesizing and secreting high-molecular-weight glycoproteins known as mucins. Human intestinal goblet cells secrete the MUC2 mucin, as well as a number of typical mucus components: CLCA1, FCGBP, AGR2, ZG16, and TFF3. GO:0043605 cellular amide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043605 The chemical reactions and pathways resulting in the breakdown of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group. GO:0043604 amide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043604 The chemical reactions and pathways resulting in the formation of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group. UBERON:0005484 tricuspid valve leaflet biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005484 tricuspid valve leaflet|leaflet of tricuspid valve|tricuspid valve leaflets|tricuspid valvular leaflet A valve leaflet that is part of a tricuspid valve. GO:0043607 formamide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043607 The chemical reactions and pathways resulting in the formation of formamide, the simplest amide, HCONH2, derived from formic acid. GO:0043606 formamide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043606 formamide metabolism The chemical reactions and pathways involving formamide, the simplest amide, HCONH2, derived from formic acid. UBERON:0005483 thymus lobe biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005483 lateral lobe of thymus|lobe of thymus Either of the two lateral lobes that constitute the thymus. GO:0043601 nuclear replisome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043601 A multi-component enzymatic machine at the nuclear replication fork, which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins. GO:0043600 cytoplasmic replisome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043600 prokaryotic replisome A multi-component enzymatic machine at the cytoplasmic replication fork, which mediates DNA replication. Includes DNA primase, DNA polymerase, DNA helicase, and other proteins. GO:0043603 cellular amide metabolic process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0043603 amide metabolism The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells. GO:0043602 nitrate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043602 nitrate disassimilation|nitrate dissimilation The chemical reactions and pathways resulting in the breakdown of nitrates, inorganic or organic salts and esters of nitric acid. CHEBI:78013 linoleic acid hydroperoxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78013 GO:0043609 regulation of carbon utilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043609 Any process that modulates the frequency, rate, or extent of carbon utilization. GO:0043608 formamide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043608 The chemical reactions and pathways resulting in the breakdown of formamide, the simplest amide, HCONH2, derived from formic acid. CHEBI:78017 food propellant biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78017 UBERON:0005487 vitelline vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005487 vein of omphalomesenteric system|embryonic vitelline vein|vena vitellina|vitelline veins|vascular vitelline network|omphalomesenteric vein the paired veins that carry blood from the yolk sac back to the embryo CHEBI:78016 food gelling agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78016 GO:0004008 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004008 GO:0004007 obsolete heavy metal-exporting ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004007 heavy metal-exporting ATPase activity OBSOLETE. Catalysis of the reaction: heavy metal ion(in) + ATP + H2O = heavy metal ion(out) + ADP + phosphate. GO:0004009 obsolete ATP-binding cassette (ABC) transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004009 ATP-binding cassette (ABC) transporter activity OBSOLETE. (Was not defined before being made obsolete). GO:0004004 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004004 GO:0004003 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004003 GO:0004006 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004006 GO:0004005 obsolete plasma membrane cation-transporting ATPase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004005 plasma membrane cation-transporting ATPase OBSOLETE. (Was not defined before being made obsolete). GO:0004000 adenosine deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004000 Reactome:R-HSA-2161195|Reactome:R-HSA-2161187|Reactome:R-HSA-74241|Reactome:R-HSA-5693346|RHEA:24408|EC:3.5.4.4|MetaCyc:ADENODEAMIN-RXN adenosine deaminase reaction|adenosine aminohydrolase activity Catalysis of the reaction: adenosine + H2O = inosine + NH3. GO:0004002 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004002 GO:0004001 adenosine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004001 RHEA:20824|MetaCyc:ADENOSINE-KINASE-RXN|Reactome:R-HSA-109624|EC:2.7.1.20 adenosine 5-phosphotransferase activity|ATP:adenosine 5'-phosphotransferase activity|adenosine kinase (phosphorylating) Catalysis of the reaction: ATP + adenosine = ADP + AMP. GO:0018649 tetrahydrofuran hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018649 EC:1.14.13.-|UM-BBD_reactionID:r0017 Catalysis of the reaction: tetrahydrofuran + O2 + 2 H+ + 2 e- = H2O + 2-hydroxytetrahydrofuran. GO:0018648 methanesulfonate monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018648 MetaCyc:RXN-9770|RHEA:26077|EC:1.14.13.111 mesylate monooxygenase activity|methanesulphonic acid monooxygenase activity|methanesulfonate,NADH:oxygen oxidoreductase activity|MSAMO activity|methanesulfonate,FMNH2:oxygen oxidoreductase activity|MSA monooxygenase activity|methanesulfonic acid monooxygenase activity Catalysis of the reaction: methanesulfonate + NADH + H+ + O2 = formaldehyde + NAD+ + sulfite + H2O. CHEBI:30081 dicarbide(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30081 GO:0018645 alkene monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018645 MetaCyc:1.14.13.69-RXN|RHEA:11792|EC:1.14.13.69|UM-BBD_enzymeID:e0039 alkene,NADH:oxygen oxidoreductase activity|alkene epoxygenase activity Catalysis of the reaction: propene + NADH + H+ + O2 = 1,2-epoxypropane + NAD+ + H2O. GO:0018644 toluene 2-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018644 MetaCyc:TOLUENE-2-MONOOXYGENASE-RXN|UM-BBD_enzymeID:e0222|EC:1.14.13.-|RHEA:20349 Catalysis of the reaction: toluene + 1/2 O2 = 2-hydroxytoluene. GO:0018647 phenanthrene 1,2-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018647 UM-BBD_enzymeID:e0333|EC:1.14.13.- Catalysis of the reaction: phenanthrene + O2 + NADH + H+ = H2O + NAD+ + phenanthrene-1,2-oxide. GO:0018646 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018646 UM-BBD_reactionID:r0736|EC:1.14.13.- Catalysis of the reaction: (1S,4R)-1-hydroxy-2-oxolimonene + NADPH + O2 = NADP+ + OH- + (3R)-3-isopropenyl-6-oxoheptanoate. GO:0018641 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018641 EC:1.14.13.-|UM-BBD_reactionID:r0048 Catalysis of the reaction: 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + O2 + 2 H+ + 2 e- = H2O + 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline. GO:0018640 dibenzothiophene monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018640 RHEA:49076|MetaCyc:RXN-621|UM-BBD_enzymeID:e0214|EC:1.14.13.- Catalysis of the reaction: dibenzothiophene + NADH + H+ + O2 = dibenzothiophene-5-oxide + NAD+ + H2O. GO:0018643 carbon disulfide oxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018643 EC:1.14.13.-|UM-BBD_reactionID:r0599 carbon disulphide oxygenase activity Catalysis of the reaction: carbon disulfide + NADH + H+ + O2 = [S] + H2O + NAD+ + carbonyl sulfide. GO:0018642 chlorophenol 4-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018642 UM-BBD_enzymeID:e0252|EC:1.14.13.- Catalysis of the addition or substitution of an OH group on C4 of a halogenated phenol. CHEBI:30089 acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30089 NCBITaxon:7496 Pterygota organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_7496 winged insects|Pterygota CHEBI:30088 gibberellin A12 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30088 CHEBI:30087 guanidinium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30087 GO:0004019 adenylosuccinate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004019 KEGG_REACTION:R01135|EC:6.3.4.4|RHEA:15753|Reactome:R-HSA-111524|MetaCyc:ADENYLOSUCCINATE-SYNTHASE-RXN succinoadenylic kinosynthetase activity|IMP--aspartate ligase activity|succino-AMP synthetase activity|adenylosuccinate synthetase activity|IMP:L-aspartate ligase (GDP-forming) Catalysis of the reaction: L-aspartate + GTP + IMP = N(6)-(1,2-dicarboxyethyl)-AMP + GDP + 3 H(+) + phosphate. GO:0004018 N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004018 RHEA:16853|EC:4.3.2.2|KEGG_REACTION:R01083|Reactome:R-HSA-73800|Reactome:R-HSA-73828|MetaCyc:AMPSYN-RXN succino AMP-lyase activity|6-N-(1,2-dicarboxyethyl)AMP AMP-lyase activity|adenylosuccinate lyase activity|N6-(1,2-dicarboxyethyl)AMP AMP-lyase activity|adenylosuccinase activity Catalysis of the reaction: N6-(1,2-dicarboxyethyl)AMP = fumarate + AMP. GO:0004015 adenosylmethionine-8-amino-7-oxononanoate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004015 EC:2.6.1.62|KEGG_REACTION:R03231|RHEA:16861|MetaCyc:DAPASYN-RXN 7,8-diaminonanoate transaminase activity|7-keto-8-aminopelargonic acid aminotransferase activity|7,8-diaminononanoate transaminase activity|DAPA transaminase activity|7-keto-8-aminopelargonic acid|adenosylmethionine--8-amino-7-oxononanoate aminotransferase activity|S-adenosyl-L-methionine:8-amino-7-oxononanoate aminotransferase activity|7,8-diaminopelargonic acid aminotransferase activity|adenosylmethionine-8-amino-7-oxononanoate aminotransferase activity|7,8-diaminononanoate aminotransferase activity|diaminopelargonate synthase activity|DAPA aminotransferase activity|adenosyl methionine-8-amino-7-oxononanoate transaminase activity|7,8-diamino-pelargonic acid aminotransferase activity Catalysis of the reaction: 8-amino-7-oxononanoate + S-adenosyl-L-methionine(1+) = 7,8-diaminononanoate + S-adenosyl-4-methylthio-2-oxobutanoate. GO:0004014 adenosylmethionine decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004014 KEGG_REACTION:R00178|EC:4.1.1.50|RHEA:15981|MetaCyc:SAMDECARB-RXN|Reactome:R-HSA-351222 S-adenosylmethionine decarboxylase activity|adenosyl methionine decarboxylase activity|S-adenosyl-L-methionine carboxy-lyase activity|S-adenosyl-L-methionine carboxy-lyase [(5-deoxy-5-adenosyl)(3-aminopropyl)-methylsulfonium-salt-forming]|S-adenosyl-L-methionine decarboxylase activity Catalysis of the reaction: S-adenosyl-L-methionine + H(+) = S-adenosylmethioninamine + CO(2). GO:0004017 adenylate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004017 RHEA:12973|EC:2.7.4.3|Reactome:R-HSA-110141|Reactome:R-HSA-74220|Reactome:R-HSA-110145|Reactome:R-HSA-110144|MetaCyc:ADENYL-KIN-RXN ATP:AMP phosphotransferase activity|5'-AMP-kinase activity|adenylic kinase activity|adenylokinase activity|myokinase activity Catalysis of the reaction: ATP + AMP = 2 ADP. GO:0004016 adenylate cyclase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004016 Reactome:R-HSA-392129|Reactome:R-HSA-170676|RHEA:15389|Reactome:R-HSA-5211224|MetaCyc:ADENYLATECYC-RXN|EC:4.6.1.1|Reactome:R-HSA-381607|Reactome:R-HSA-164377|Reactome:R-HSA-5610727 3',5'-cyclic AMP synthetase activity|adenylyl cyclase activity|ATP diphosphate-lyase (cyclizing) activity|ATP pyrophosphate-lyase activity|cAMP generating peptide activity|adenyl cyclase activity|adenylylcyclase activity|ATP diphosphate-lyase (cyclizing; 3',5'-cyclic-AMP-forming) activity Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate. GO:0004011 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004011 GO:0004010 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004010 GO:0004013 adenosylhomocysteinase activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0004013 Reactome:R-HSA-5579084|EC:3.3.1.1|MetaCyc:ADENOSYLHOMOCYSTEINASE-RXN|Reactome:R-HSA-174401|RHEA:21708 adenosylhomocysteine hydrolase activity|S-adenosylhomocysteine hydrolase activity|SAHase activity|S-adenosylhomocysteine synthase activity|AdoHcyase activity|S-adenosyl-L-homocysteine hydrolase activity|S-adenosylhomocysteinase activity Catalysis of the reaction: S-adenosyl-L-homocysteine + H2O = adenosine + L-homocysteine. GO:0004012 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004012 CHEBI:30095 hydrazinide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30095 GO:0018659 4-hydroxybenzoate 3-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018659 MetaCyc:4-HYDROXYBENZOATE-3-MONOOXYGENASE-RXN|EC:1.14.13.2|UM-BBD_reactionID:r0109|RHEA:19477 p-hydroxybenzoate hydroxylase activity|p-hydroxybenzoic acid hydrolase activity|4-hydroxybenzoate 3-hydroxylase activity|p-hydroxybenzoate hydrolyase activity|para-hydroxybenzoate hydroxylase activity|p-hydroxybenzoic acid hydroxylase activity|p-hydroxybenzoate-3-hydroxylase activity|4-hydroxybenzoate,NADPH:oxygen oxidoreductase (3-hydroxylating)|4-hydroxybenzoate monooxygenase activity|p-hydroxybenzoic hydroxylase activity Catalysis of the reaction: 4-hydroxybenzoate + NADPH + H+ + O2 = protocatechuate + NADP+ + H2O. CHEBI:30094 diazenium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30094 GO:0018656 phenanthrene 3,4-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018656 UM-BBD_reactionID:r0508|EC:1.14.13.- Catalysis of the reaction: phenanthrene + O2 + NADH + H+ = H2O + NAD+ + phenanthrene-3,4-oxide. GO:0018655 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018655 EC:1.14.13.-|UM-BBD_reactionID:r0430 Catalysis of the reaction: 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA + NADH + H+ + O2 = NAD+ + H2O + delta2,5-3,4,4-trimethylpimelyl-CoA. GO:0018658 salicylate 1-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018658 UM-BBD_enzymeID:e0149|MetaCyc:SALICYLATE-1-MONOOXYGENASE-RXN|EC:1.14.13.1|RHEA:11004 salicylate hydroxylase activity|salicylate monooxygenase activity|salicylate,NADH:oxygen oxidoreductase (1-hydroxylating, decarboxylating)|salicylic hydroxylase activity|salicylate hydroxylase (decarboxylating)|salicylate 1-hydroxylase activity Catalysis of the reaction: salicylate + NADH + H+ + O2 = catechol + NAD+ + H2O + CO2. GO:0018657 toluene 3-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018657 UM-BBD_enzymeID:e0224|EC:1.14.13.-|MetaCyc:TOLUENE-3-MONOOXYGENASE-RXN Catalysis of the reaction: toluene + 1/2 O2 = 3-hydroxytoluene. GO:0018652 toluene-sulfonate methyl-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018652 MetaCyc:TSMOS-RXN|EC:1.14.13.-|RHEA:51024|UM-BBD_reactionID:r0290 toluene-sulphonate methyl-monooxygenase activity Catalysis of the reaction: toluene-4-sulfonate + NADH + O2 = NAD+ + OH- + 4-sulfobenzyl alcohol. GO:0018651 toluene-4-sulfonate monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018651 EC:1.14.13.-|UM-BBD_reactionID:r0296 toluene-4-sulphonate monooxygenase activity Catalysis of the reaction: toluene-4-sulfonate + 1/2 O2 + H+ = HSO3(-) + 4-hydroxytoluene. GO:0018654 2-hydroxy-phenylacetate hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018654 EC:1.14.13.-|UM-BBD_reactionID:r0252 Catalysis of the reaction: 2-hydroxyphenylacetate + NADH + O2 = NAD+ + OH- + homogentisate. GO:0018653 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018653 EC:1.14.13.-|UM-BBD_reactionID:r0046 Catalysis of the reaction: 3-methyl-2-oxo-1,2-dihydroquinoline + O2 + 2 H+ + 2 e- = H2O + 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline. CHEBI:30099 diazynediium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30099 GO:0018650 styrene monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018650 EC:1.14.13.-|UM-BBD_reactionID:r0225 Catalysis of the reaction: styrene + NADPH + FADH + O2 = NADP+ + FAD+ + H2O + styrene oxide. CHEBI:30096 diazene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30096 CHEBI:29076 3''-adenylylstreptomycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29076 GO:0018627 2-aminobenzenesulfonate 2,3-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018627 RHEA:23468|MetaCyc:2ASDOSALCAL-RXN|KEGG_REACTION:R05156|EC:1.14.12.14|UM-BBD_reactionID:r0218 2-aminobenzenesulfonate dioxygenase activity|2-aminobenzenesulfonate,NADH:oxygen oxidoreductase (2,3-hydroxylating, ammonia-forming)|2-aminosulfobenzene 2,3-dioxygenase activity|2-aminobenzenesulphonate dioxygenase activity|2-aminobenzenesulphonate 2,3-dioxygenase activity Catalysis of the reaction: 2-aminobenzenesulfonate + 2 H(+) + NADH + O(2) = 2,3-dihydroxybenzenesulfonate + NAD(+) + NH(4)(+). 2,3-dihydroxybenzenesulfonate is also known as 3-sulfocatechol. CHEBI:29084 (2->1)-beta-D-fructan biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29084 GO:0018626 2-chlorobenzoate 1,2-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018626 UM-BBD_reactionID:r0632|RHEA:21652|MetaCyc:2-CHLOROBENZOATE-12-DIOXYGENASE-RXN|EC:1.14.12.13 2-halobenzoate 1,2-dioxygenase activity|2-chlorobenzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating, dechlorinating, decarboxylating) Catalysis of the reaction: 2-chlorobenzoate + NADH + H+ + O2 = catechol + chloride + NAD+ + CO2. CHEBI:29083 N-methyl-L-glutamate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29083 GO:0018629 2-hydroxyquinoline 5,6-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018629 MetaCyc:1.14.12.16-RXN|RHEA:10976|UM-BBD_reactionID:r0052|EC:1.14.12.16 quinolin-2(1H)-one 5,6-dioxygenase activity|2-oxo-1,2-dihydroquinoline 5,6-dioxygenase activity|quinolin-2-ol 5,6-dioxygenase activity|quinolin-2-ol,NADH:oxygen oxidoreductase (5,6-hydroxylating) Catalysis of the reaction: quinolin-2-ol + NADH + H+ + O2 = 2,5,6-trihydroxy-5,6-dihydroquinoline + NAD+. CHEBI:29086 3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29086 GO:0018628 terephthalate 1,2-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018628 MetaCyc:1.14.12.15-RXN|RHEA:10312|KEGG_REACTION:R05148|UM-BBD_reactionID:r0150|EC:1.14.12.15 benzene-1,4-dicarboxylate 1,2-dioxygenase activity|benzene-1,4-dicarboxylate,NADH:oxygen oxidoreductase (1,2-hydroxylating)|1,4-dicarboxybenzoate 1,2-dioxygenase activity Catalysis of the reaction: H(+) + NADH + O(2) + terephthalate = (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD(+). GO:0018623 benzoate 1,2-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018623 RHEA:12633|MetaCyc:BENZOATE-12-DIOXYGENASE-RXN|EC:1.14.12.10|UM-BBD_enzymeID:e0154 benzoic hydroxylase activity|benzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating)|benzoate dioxygenase activity|benzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating, decarboxylating)|benzoate hydroxylase activity Catalysis of the reaction: benzoate + NADH + H+ + O2 = catechol + CO2 + NAD+. GO:0018622 4-chlorophenylacetate 3,4-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018622 KEGG_REACTION:R03306|RHEA:14689|MetaCyc:1.14.12.9-RXN|EC:1.14.12.9|UM-BBD_reactionID:r0308 4-chlorophenylacetate,NADH:oxygen oxidoreductase (3,4-hydroxylating, dechlorinating) Catalysis of the reaction: 4-chlorophenylacetate + NADH + O(2) = 3,4-dihydroxyphenylacetate + chloride + NAD(+). GO:0018625 naphthalene 1,2-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018625 MetaCyc:NAPHTHALENE-12-DIOXYGENASE-RXN|RHEA:19173|EC:1.14.12.12|UM-BBD_enzymeID:e0002 naphthalene,NADH:oxygen oxidoreductase (1,2-hydroxylating)|naphthalene dioxygenase activity|naphthalene oxygenase activity Catalysis of the reaction: naphthalene + NADH + H+ + O2 = (1R,2S)-1,2-dihydronaphthalene-1,2-diol + NAD+. GO:0018624 toluene dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018624 KEGG_REACTION:R03559|RHEA:16737|MetaCyc:TOLUENE-DIOXYGENASE-RXN|EC:1.14.12.11|UM-BBD_enzymeID:e0155 toluene 1,2-dioxygenase activity|toluene 2,3-dioxygenase activity|toluene,NADH:oxygen oxidoreductase (1,2-hydroxylating) Catalysis of the reaction: H(+) + NADH + O(2) + toluene = (1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol + NAD(+). CHEBI:29081 synephrine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29081 GO:0018621 4-sulfobenzoate 3,4-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018621 MetaCyc:4-SULFOBENZOATE-34-DIOXYGENASE-RXN|UM-BBD_reactionID:r0293|EC:1.14.12.8|RHEA:13937|KEGG_REACTION:R01636 4-sulfobenzoate,NADH:oxygen oxidoreductase (3,4-hydroxylating, sulfite-forming)|4-sulfobenzoate dioxygenase activity|4-sulphobenzoate 3,4-dioxygenase activity|4-sulfobenzoate 3,4-dioxygenase system Catalysis of the reaction: 4-sulfobenzoate + H(+) + NADH + O(2) = 3,4-dihydroxybenzoate + NAD(+) + sulfite. GO:0018620 phthalate 4,5-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018620 UM-BBD_reactionID:r0102|KEGG_REACTION:R03630|RHEA:17489|MetaCyc:PHTHALATE-45-DIOXYGENASE-RXN|EC:1.14.12.7 phthalate dioxygenase activity|PDO activity|phthalate,NADH:oxygen oxidoreductase (4,5-hydroxylating) Catalysis of the reaction: H(+) + NADH + O(2) + phthalate = cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD(+). CHEBI:30066 thioglycolate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30066 CHEBI:30065 thioglycolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30065 NCBITaxon:41087 Elateriformia organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_41087 CHEBI:29089 1,2-diacyl-sn-glycerol 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29089 GO:0018638 toluene 4-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018638 UM-BBD_enzymeID:e0225|EC:1.14.13.- Catalysis of the reaction: toluene + 1/2 O2 = 4-hydroxytoluene. GO:0018637 1-hydroxy-2-naphthoate hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018637 EC:1.14.13.-|UM-BBD_reactionID:r0491 Catalysis of the reaction: 1-hydroxy-2-naphthoate + O2 + NADPH + 2 H+ = NADP+ + H2O + CO2 + 1,2-dihydroxynaphthalene. CHEBI:29094 homoisocitric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29094 GO:0018639 xylene monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018639 EC:1.14.13.-|UM-BBD_enzymeID:e0172 Catalysis of the reactions: toluene + 1/2 O2 = benzyl alcohol, and xylene + 1/2 O2 = methylbenzyl alcohol. GO:0018634 alpha-pinene monooxygenase [NADH] activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018634 EC:1.14.13.-|UM-BBD_reactionID:r0742 Catalysis of the reaction: alpha-pinene + NADH + H+ + O2 = NAD+ + H2O + alpha-pinene oxide. CHEBI:29091 nocardicin E biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29091 GO:0018633 dimethyl sulfide monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018633 UM-BBD_reactionID:r0208|EC:1.14.13.- dimethyl sulphide monooxygenase activity Catalysis of the reaction: dimethyl sulfide + NADH + O2 = NAD+ + OH- + methanethiol + formaldehyde. NCBITaxon:41084 Polyphaga organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_41084 Polyphaga CHEBI:29090 D-2-aminohexano-6-lactam biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29090 GO:0018636 phenanthrene 9,10-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018636 EC:1.14.13.-|UM-BBD_reactionID:r0495 Catalysis of the reaction: phenanthrene + O2 + NADH + H+ = H2O + NAD+ + phenanthrene-9,10-oxide. GO:0018635 (R)-limonene 1,2-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018635 EC:1.14.13.107|MetaCyc:RXN-9407|UM-BBD_reactionID:r0733|KEGG_REACTION:R09393|KEGG_REACTION:R06398 (+)-limonene 1,2-monooxygenase activity|(+)-limonene,NAD(P)H:oxygen oxidoreductase activity|(R)-limonene,NAD(P)H:oxygen oxidoreductase activity Catalysis of the reaction: (4R)-limonene + NAD(P)H + H+ + O2 = NAD(P)+ + H2O + (4R)-limonene-1,2-epoxide. GO:0018630 3,5-xylenol methylhydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018630 MetaCyc:3-5-XYLENOL-METHYLHYDROXYLASE-RXN|EC:1.14.13.-|UM-BBD_reactionID:r0081 Catalysis of the reaction: 3-hydroxytoluene + NADH + O2 = NAD+ + OH- + 3-hydroxybenzyl alcohol. GO:0018632 4-nitrophenol 4-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018632 MetaCyc:RXN-8739|EC:1.14.13.-|UM-BBD_reactionID:r0226|RHEA:34327 Catalysis of the reaction: p-nitrophenol + O2 + NADPH = H2O + NADP+ + nitrite + p-benzoquinone. GO:0018631 phenylacetate hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018631 EC:1.14.13.-|UM-BBD_reactionID:r0036 Catalysis of the reaction: phenylacetate + NADH + O2 = NAD+ + OH- + 2-hydroxyphenylacetate. CHEBI:30049 teichoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30049 GO:0018609 chlorobenzene dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018609 EC:1.14.12.-|UM-BBD_enzymeID:e0062 Catalysis of the reaction: 2,3-unsubstituted benzenoid + O2 + NAD(P)H + H+ = 2,3-cis-dihydroxydihydrobenzenoid + NAD(P)+. Substrates include 1,4-dichlorobenzene (forms 3,6-dichloro-cis-1,2-dihydroxycyclohexa-3,5-diene), 1,2,3,4-tetrachlorobenzene (forms cis-chlorobenzene dihydrodiol) and 1,2,4-trichlorobenzene (forms 3,4,6-trichloro-cis-1,2-dihydroxycyclohexa-3,5-diene). CHEBI:29055 3,4-dihydroxyphenylpyruvate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29055 GO:0018608 1-indanone dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018608 UM-BBD_reactionID:r0416|EC:1.14.12.- Catalysis of the reaction: 1-indanone + NADPH + 1/2 O2 = NADP+ + 3-hydroxy-1-indanone. CHEBI:29057 keratan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29057 CHEBI:29056 lipid IVA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29056 GO:0018605 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018605 CHEBI:29062 GDP-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29062 GO:0018604 4-aminobenzoate 3,4-dioxygenase (deaminating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018604 EC:1.14.12.-|UM-BBD_reactionID:r0566 Catalysis of the reaction: 4-aminobenzoate + 2 H+ + O2 + 2 e- = NH3 + 3,4-dihydroxybenzoate. GO:0018607 1-indanone monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018607 UM-BBD_reactionID:r0417|EC:1.14.12.- Catalysis of the reaction: 1-indanone + NADPH + 1/2 O2 = NADP+ + 3,4-dihydrocoumarin. CHEBI:29064 1,6,6-trimethyl-2,7-dioxabicyclo[3.2.2]nonan-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29064 GO:0018606 benzenesulfonate dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018606 EC:1.14.12.-|UM-BBD_reactionID:r0295 benzenesulphonate dioxygenase activity Catalysis of the reaction: toluene-4-sulfonate + NADH + O2 + H+ = NAD+ + HSO3(-) + 4-methylcatechol. CHEBI:29063 L-mimosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29063 GO:0018601 4-nitrophenol 2-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018601 RHEA:12568|MetaCyc:4-NITROPHENOL-2-MONOOXYGENASE-RXN|UM-BBD_reactionID:r0230|KEGG_REACTION:R03023|EC:1.14.13.29 4-nitrophenol-2-hydroxylase activity|4-nitrophenol hydroxylase activity|4-nitrophenol,NADH:oxygen oxidoreductase (2-hydroxylating) Catalysis of the reaction: 4-nitrophenol + H(+) + NADH + O(2) = 4-nitrocatechol + H(2)O + NAD(+). GO:0018600 alpha-pinene dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018600 UM-BBD_reactionID:r0709|EC:1.14.-.- Catalysis of the reaction: alpha-pinene + O2 + 2 H+ + 2 e- = H2O + myrtenol. GO:0018603 nitrobenzene 1,2-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018603 UM-BBD_reactionID:r0306|EC:1.14.12.- Catalysis of the reaction: nitrobenzene + NADH + O2 = NAD+ + nitrite + catechol. CHEBI:29060 alpha-pinene oxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29060 GO:0018602 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018602 MetaCyc:RXN-9863|UM-BBD_reactionID:r0274|RHEA:48984 Catalysis of the reaction: 2,4-dichlorophenoxyacetate + 2-oxoglutarate + oxygen = 2,4-dichlorophenol + glyoxylate + succinate + CO2. UBERON:0005434 cervical region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005434 subdivision of neck|neck subdivision|cervical region|region of neck CHEBI:30043 terephthalate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30043 CHEBI:30042 taxa-4(20),11-dien-5alpha-yl acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30042 UBERON:0005432 aortic sac biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005432 saccus aorticus The dilated structure that is lined by endothelial cells and located at the arterial pole of the heart just above (distal to) the truncus arteriosus in mammalian embryos; it is the primordial vascular channel from which the aortic arches (and eventually the dorsal aortae) arise; the aortic sac is homologous to the ventral aorta of gill-bearing vertebrates CHEBI:30041 taxa-4(20),11-dien-5alpha,13alpha-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30041 CHEBI:44680 3-oxooctanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_44680 UBERON:0005419 pectoral appendage bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005419 pectoral fin buds|forelimb - pectoral fin bud|pectoral fin bud A limb bud that develops into a forelimb or pectoral fin. UBERON:0005418 hindlimb bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005418 leg bud|limb bud - hindlimb|hind limb bud|posterior limb bud A limb bud that develops into a hindlimb. CHEBI:29069 phthalic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29069 GO:0018619 benzene 1,2-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018619 EC:1.14.12.3|RHEA:13813|MetaCyc:BENZENE-12-DIOXYGENASE-RXN|UM-BBD_reactionID:r0079|KEGG_REACTION:R03543 benzene hydroxylase activity|benzene,NADH:oxygen oxidoreductase (1,2-hydroxylating)|benzene dioxygenase activity Catalysis of the reaction: benzene + H(+) + NADH + O(2) = cis-cyclohexa-3,5-diene-1,2-diol + NAD(+). CHEBI:29065 N-acetyl-O-acetylneuraminate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29065 CHEBI:29067 carboxylic acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29067 GO:0018616 trihydroxytoluene dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018616 MetaCyc:R305-RXN|EC:1.14.12.-|UM-BBD_reactionID:r0093 Catalysis of the reaction: 2,3,5-trihydroxytoluene + O2 = 2,4,6-trioxoheptanoate. CHEBI:29073 L-ascorbic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29073 UBERON:0005420 pelvic appendage bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005420 hindlimb/pelvic fin bud|pelvic fin buds|pelvic fin bud A limb bud that develops into a hindlimb or pelvic fin. GO:0018615 2-indanone monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018615 UM-BBD_reactionID:r0424|EC:1.14.12.- Catalysis of the reaction: 2-indanone + NADPH + 1/2 O2 = NADP+ + 3-isochromanone. GO:0018618 anthranilate 1,2-dioxygenase (deaminating, decarboxylating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018618 MetaCyc:1.14.12.1-RXN|EC:1.14.12.1|UM-BBD_reactionID:r0577 anthranilic acid hydroxylase activity|anthranilate 1,2-dioxygenase|anthranilate dioxygenase reductase|anthranilate,NAD(P)H:oxygen oxidoreductase (1,2-hydroxylating, deaminating, decarboxylating)|AntC|anthranilate hydroxylase activity|AntB|AntA|anthranilate dioxygenase activity|anthranilic hydroxylase activity Catalysis of the reaction: anthranilate + NADPH + H+ + O2 = catechol + CO2 + NADP+ + NH3. CHEBI:29075 mononucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29075 GO:0018617 4-aminobenzenesulfonate 3,4-dioxygenase (deaminating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018617 EC:1.14.12.-|UM-BBD_reactionID:r0580 4-aminobenzenesulphonate 3,4-dioxygenase (deaminating) activity Catalysis of the reaction: 4-aminobenzenesulfonate + 2 H+ + O2 + 2 e- = NH3 + 4-sulfocatechol. CHEBI:29074 dolichyl palmitate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29074 GO:0018612 dibenzothiophene dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018612 EC:1.14.12.-|UM-BBD_reactionID:r0160 Catalysis of the reaction: dibenzothiophene + NADH + O2 + H+ = NAD+ + cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene. GO:0018611 toluate dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018611 EC:1.14.12.-|UM-BBD_enzymeID:e0190 Catalysis of the reaction: methylbenzoate + NADH + O2 + H+ = NAD+ + 1,2-dihydroxymethylcyclohexa-3,5-dienecarboxylate. GO:0018614 ethylbenzene dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018614 EC:1.14.12.-|UM-BBD_reactionID:r0247 Catalysis of the reaction: ethylbenzene + O2 + NADH + H+ = NAD+ + cis-2,3-dihydroxy-2,3-dihydroethylbenzene. CHEBI:29071 3-deoxy-D-glycero-hexo-2,5-diulosonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29071 GO:0018613 9-fluorenone dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018613 UM-BBD_reactionID:r0409|EC:1.14.12.- Catalysis of the reaction: 9-fluorenone + 2 NADPH + O2 = 2 NADP+ + 3,4-dihydroxy-3,4-dihydro-9-fluorenone. UBERON:0005428 vagal neural crest biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005428 VNC|post-otic neural crest|enteric neural crest Vagal neural crest is adjacent to the first seven somites gives rise to both ganglionic and ectomesenchymal derivatives[ZFA]. UBERON:0005427 corneal primordium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005427 Portion of tissue that is part of the eye and gives rise to the mature, fully layered cornea. UBERON:0005426 lens vesicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005426 immature lens|presumptive lens|hollow lens vesicle|lens mass|solid lens vesicle Portion of tissue that gives rise to the lens. GO:0018610 dibenzofuran 4,4a-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018610 MetaCyc:R606-RXN|UM-BBD_enzymeID:e0030|EC:1.14.12.-|RHEA:42460 Catalysis of the reaction: dibenzofuran + NADH + H+ + O2 = 2,2',3-trihydroxybiphenyl + NAD+. UBERON:0005425 presumptive neural retina biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005425 presumptive retina|future neural layer|future neural epithelium|presumptive retinas|future neural retina|future NR|future retinal neural layer|inner layer optic cup|optic cup inner layer Portion of tissue that is the inner layer of the optic cup and will become the neural retina. UBERON:0005424 presumptive retinal pigmented epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005424 presumptive pigmented epithelium|future RPE|future retinal pigmented epithelium|presumptive pigmented epithelia|future pigmented retinal epithelium|future PRE|future pigmented layer|optic cup outer layer|outer layer optic cup Portion of tissue that is the outer layer of the optic cup and will become the retinal pigmented epithelium. UBERON:0005423 developing anatomical structure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005423 developmental tissue|developmental structure|developing structure UBERON:0005422 pelvic appendage apical ectodermal ridge biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005422 apical ectodermal ridge pelvic fin bud|apical ectodermal ridge hind limb|leg AER|apical ectodermal ridge hindlimb|AER hindlimb|lower lmb bud apical ectodermal ridge An apical ectodermal ridge that is part of a pelvic appendage bud. UBERON:0005421 pectoral appendage apical ectodermal ridge biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005421 wing apical ectodermal ridge|AER forelimb|apical ectodermal ridge pectoral fin|wing AER|apical ectodermal ridge pectoral fin bud|upper limb bud apical ectodermal ridge|apical ectodermal ridge forelimb|apical fold pectoral fin|aer pectoral fin An apical ectodermal ridge that is part of a pectoral appendage bud. UBERON:0005409 alimentary part of gastrointestinal system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005409 GI tract|gastroenterological system|gastrointestinal (GI) tract|gastro-intestinal system|gastrointestinal tract|gastrointestinal system|alimentary system|alimentary tract The part of the digestive system that excludes the hepatobiliary system. UBERON:0005408 circumventricular organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005408 circumventricular organ|circumventricular organ of neuraxis|CVO Any of any of the secretory or sensory organs located in the brain region around or in relation to the ventricular system that are characterized by extensive vasculature and a lack of a normal blood brain barrier (BBB) and allow for the linkage between the central nervous system and peripheral blood flow. CHEBI:44678 alpha-D-glucosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_44678 CHEBI:29036 copper(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29036 CHEBI:29039 1,2-diacyl-sn-glycero-3-phospho-1'-(3'-O-L-lysyl)-sn-glycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29039 CHEBI:29033 iron(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29033 CHEBI:29032 (R)-pantothenate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29032 CHEBI:29035 manganese(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29035 CHEBI:29034 iron(3+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29034 CHEBI:29042 alpha-D-glucose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29042 CHEBI:29041 manganese(3+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29041 UBERON:0005417 forelimb bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005417 limb bud - forelimb|anterior limb bud|arm bud|upper limb bud|wing bud A limb bud that develops into a forelimb. CHEBI:30023 trans-sinapate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30023 CHEBI:30022 D-selenomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30022 CHEBI:30021 L-selenomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30021 UBERON:0005411 bony otic capsule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005411 otic capsule bone the cartilage or bony capsule surrounding the inner ear mechanism UBERON:0005410 cartilaginous otic capsule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005410 auditory capsule|otic capsule cartilage element A otic capsule endochondral element that is composed primarily of cartilage tissue. CHEBI:30038 taxa-4(20),11-dien-5alpha-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30038 CHEBI:68612 EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68612 CHEBI:44667 L-ornithinium(2+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_44667 CHEBI:44666 2'-O-methylcytidine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_44666 CHEBI:29044 2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29044 CHEBI:29043 O-beta-D-glucosyl-cis-zeatin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29043 CHEBI:29045 maleamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29045 CHEBI:29051 D-mannosyl undecaprenyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29051 CHEBI:29053 pyridine-3,4-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29053 CHEBI:29052 D-glyceraldehyde 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29052 CHEBI:30037 taxa-4,11-diene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30037 UBERON:0005404 frontonasal suture biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005404 frontonasal suture of skull|articulation of the nasal bone with frontal bone A suture between frontal and nasal bones UBERON:0005403 ventral striatum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005403 striatum ventral region|striatum ventrale A composite structure of the telencephalon that is defined in the striatopallidal system by connectivity and neurochemical staining. It includes the nucleus accumbens, the most ventral portions of the caudate nucleus and the putamen, the rostrolateral portion of the anterior perforated substance, the islands of Calleja and a rostral subcommissural portion of substantia innominata. The boundary between the ventral striatum and dorsal striatum is indistinct in sections stained for Nissl substance (Heimer-1995; adapted from Brain Info). CHEBI:30033 bacteriochlorophyll a biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30033 UBERON:0005401 cerebral hemisphere gray matter biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005401 cerebral gray matter|cerebral hemisphere grey matter|cerebral grey matter A gray matter that is part of a cerebral hemisphere. UBERON:0005400 telencephalon arachnoid mater biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005400 telencephalon arachnoid matter An arachnoid mater that is part of a telencephalon. CHEBI:30031 succinate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30031 GO:0102630 gossypetin 8-methyl ester 3'-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102630 MetaCyc:RXN-15536 Catalysis of the reaction: 3',4',5,7-pentahydroxy-8-methoxyflavon-3-olate + S-adenosyl-L-methionine <=> gossypetin 3',8-dimethyl ether + S-adenosyl-L-homocysteine + H+. GO:0102632 (S)-nandinine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102632 EC:1.14.19.73|RHEA:50364|MetaCyc:RXN-15538 Catalysis of the reaction: (S)-scoulerine + NADPH + H+ + O2 <=> (S)-nandinine + NADP + 2 H2O. GO:0102631 caffeoylglucose 3-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102631 MetaCyc:RXN-15537 Catalysis of the reaction: 1-O-caffeoyl-beta-D-glucose + S-adenosyl-L-methionine <=> 1-O-feruloyl-beta-D-glucose + S-adenosyl-L-homocysteine + H+. GO:0102634 1,3,6,8-tetrahydroxynaphthalene monooxygenase (quinone-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102634 MetaCyc:RXN-15586 Catalysis of the reaction: naphthalene-1,3,6,8-tetrol + O2 <=> flaviolin-2-olate + H2O + H+. GO:0102633 flaviolin monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102633 MetaCyc:RXN-15585 Catalysis of the reaction: flaviolin-2-olate + NADH + H+ + O2 <=> mompain + NAD + H2O. GO:0102636 3-benzyl-3,6 -bis(glutathione)- 6-(hydroxymethyl)-diketopiperazine gamma-glutamylcyclotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102636 MetaCyc:RXN-15681 Catalysis of the reaction: 3-benzyl-3,6 -bis(glutathione)- 6-(hydroxymethyl)-diketopiperazine <=> 3-benzyl-3,6 -bis(cysteinylglycine)- 6-(hydroxymethyl)-diketopiperazine + 2 5-oxo-L-prolinate. GO:0102635 11-deoxycorticosterone reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102635 RHEA:47716|MetaCyc:RXN-15607 Catalysis of the reaction: 11-deoxycorticosterone + NADH + H+ <=> 4-pregnen-20,21-diol-3-one + NAD. GO:0102638 [1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102638 MetaCyc:RXN-15734|EC:2.5.1.105 Catalysis of the reaction: 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + [1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl diphosphate = [1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + diphosphoric acid. GO:0102637 5-aminolevulinate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102637 MetaCyc:RXN-15714 Catalysis of the reaction: 5-ammoniolevulinate + coenzyme A + ATP <=> 5-aminolevulinyl-CoA + AMP + diphosphoric acid. GO:0102639 paspalicine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102639 MetaCyc:RXN-15737 Catalysis of the reaction: 13-desoxypaxilline + NADPH + O2 + H+ <=> paspalicine + NADP + 2 H2O. GO:0102641 (R)-lactaldehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102641 MetaCyc:RXN-15743 Catalysis of the reaction: (R)-propane-1,2-diol + NADP <=> (R)-lactaldehyde + NADPH + H+. GO:0102640 paspalinine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102640 MetaCyc:RXN-15738 Catalysis of the reaction: paspalicine + O2 + NADPH + H+ <=> paspalinine + NADP + H2O. GO:0102643 scalarane-17alpha-19-diol synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102643 MetaCyc:RXN-15755 Catalysis of the reaction: scalarane-17alpha-19-diol <=> all-trans-geranylfarnesol + H2O. GO:0102645 17(E)-cheilanthenediol synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102645 MetaCyc:RXN-15758 Catalysis of the reaction: 17(E)-cheilanthenediol <=> all-trans-geranylfarnesol + H2O. GO:0102644 monocyclic sesterterpenediol synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102644 MetaCyc:RXN-15756 Catalysis of the reaction: monocyclic sesterterpenediol <=> all-trans-geranylfarnesol + H2O. GO:0102647 D-ribose 5-phosphate:D-sedoheptulose 7-phosphate transaldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102647 MetaCyc:RXN-15789 Catalysis of the reaction: sedoheptulose 7-phosphate + D-ribose 5-phosphate <=> D-glycero-D-altro-octulose 8-phosphate + D-erythrose 4-phosphate. GO:0102646 14betaH-scalarane-17alpha-19-diol synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102646 MetaCyc:RXN-15759 Catalysis of the reaction: 14betaH-scalarane-17alpha-19-diol <=> all-trans-geranylfarnesol + H2O. GO:0102649 acetoacetyl-ACP synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102649 MetaCyc:RXN-15810 Catalysis of the reaction: acetyl-CoA + malonyl-CoA + H+ + a holo-[acyl-carrier protein] <=> acetoacetyl-ACP + 2 coenzyme A + carbon dioxide. GO:0102648 D-ribose 5-phosphate:D-fructose 6-phosphate transaldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102648 MetaCyc:RXN-15790 Catalysis of the reaction: D-fructose 6-phosphate + D-ribose 5-phosphate <=> D-glycero-D-altro-octulose 8-phosphate + D-glyceraldehyde 3-phosphate. GO:0102650 cyclo-acetoacetyl-L-tryptophan synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102650 MetaCyc:RXN-15811 Catalysis of the reaction: acetoacetyl-ACP + L-tryptophan + ATP <=> cyclo-acetoacetyl-L-tryptophan + AMP + diphosphoric acid + 2 H+ + a holo-[acyl-carrier protein]. GO:0004187 obsolete carboxypeptidase D activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004187 carboxypeptidase Kex1|KEX1 proteinase activity|saccharomyces cerevisiae KEX1 gene product|carboxypeptidase S1 activity|CPDW-II|KEX1DELTAp|gene KEX1 serine carboxypeptidase|KEX1 carboxypeptidase activity|carboxypeptidase KEX1 activity|cereal serine carboxypeptidase II|carboxypeptidase D activity OBSOLETE. Catalysis of the preferential release of a C-terminal arginine or lysine residue. Function is inhibited by diisopropyl fluorophosphate and sensitive to thiol-blocking reagents. GO:0102652 gibberellin A9,2-oxoglutarate:oxygen oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102652 MetaCyc:RXN-171 Catalysis of the reaction: gibberellin A9 + 2-oxoglutarate + O2 <=> gibberellin A51 + succinate + carbon dioxide. GO:0004186 obsolete carboxypeptidase C activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004186 lysosomal carboxypeptidase A|serine-type carboxypeptidase I activity|deamidase|serine carboxypeptidase I activity|lysosomal protective protein activity|vacuolar carboxypeptidase Y|carboxypeptidase C activity|cathepsin A activity|carboxypeptidase Y activity OBSOLETE. Catalysis of the release of a C-terminal amino acid with a broad specificity. GO:0102654 1-18:1-2-16:0-phosphatidylglycerol trans-3 desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102654 EC:1.14.19.43|RHEA:46764|MetaCyc:RXN-1725 Catalysis of the reaction: 1-[(9Z)-octadec-9-enoyl]-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) + O2 + a reduced electron acceptor <=> 1-18:1-2-trans-16:1-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor. GO:0004189 obsolete tubulinyl-Tyr carboxypeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004189 tyrosinotubulin carboxypeptidase activity|tubulinyl-Tyr carboxypeptidase activity|tubulinyltyrosine carboxypeptidase activity|tubulin-tyrosine carboxypeptidase activity|brain I carboxypeptidase activity|tubulin carboxypeptidase activity|tubulinyl-tyrosine carboxypeptidase activity|tyrosyltubulin carboxypeptidase activity|TTCPase activity|soluble carboxypeptidase activity|carboxypeptidase-tubulin activity OBSOLETE. Catalysis of the cleavage of the Glu-Tyr bond to release the C-terminal tyrosine residue from the native tyrosinated tubulin. Inactive on Z-Glu-Tyr. GO:0004188 obsolete serine-type Pro-X carboxypeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004188 proline carboxypeptidase activity|lysosomal Pro-X carboxypeptidase activity|proline-specific carboxypeptidase P|lysosomal carboxypeptidase C activity|peptidylprolylamino acid carboxypeptidase activity|prolyl carboxypeptidase activity|aminoacylproline carboxypeptidase activity|serine-type Pro-X carboxypeptidase activity|angiotensinase C activity|lysosomal Pro-Xaa carboxypeptidase activity|PCP OBSOLETE. Catalysis of the cleavage of a Pro-Xaa bond by a serine-type peptidase mechanism to release a C-terminal amino acid. GO:0102653 gibberellin A51,2-oxoglutarate:oxygen oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102653 MetaCyc:RXN-172 Catalysis of the reaction: gibberellin A51 + 2-oxoglutarate + O2 <=> H+ + gibberellin A51-catabolite + succinate + carbon dioxide + H2O. GO:0004183 obsolete carboxypeptidase E activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004183 peptidyl-L-lysine(-L-arginine) hydrolase|enkephalin-precursor endopeptidase activity|enkephalin convertase activity|insulin granule-associated carboxypeptidase activity|cobalt-stimulated chromaffin granule carboxypeptidase activity|carboxypeptidase E activity|membrane-bound carboxypeptidase activity|enkephalin precursor carboxypeptidase activity|carboxypeptidase H activity OBSOLETE. Catalysis of the reaction: peptidyl-L-lysine (or peptidyl-L-arginine) + H2O = peptide + L-lysine (or L-arginine). Function is activated by Co2+ and inhibited by 1,10-phenanthroline and other chelating agents. GO:0102656 1-18:2-2-trans-16:1-phosphatidylglycerol desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102656 MetaCyc:RXN-1727 Catalysis of the reaction: 1-18:2-2-trans-16:1-phosphatidylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-trans-16:1-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor. GO:0102655 1-18:1-2-trans-16:1-phosphatidylglycerol desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102655 EC:1.14.19.23|MetaCyc:RXN-1726 Catalysis of the reaction: 1-18:1-2-trans-16:1-phosphatidylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-trans-16:1-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor. GO:0004182 obsolete carboxypeptidase A activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004182 carboxypeptidase A activity|carboxypolypeptidase activity|tissue carboxypeptidase A|pancreatic carboxypeptidase A OBSOLETE. Catalysis of the reaction: peptidyl-L-amino acid + H2O = peptide + L-amino acid. Little or no action with -Asp, -Glu, -Arg, -Lys or -Pro. GO:0102658 2-oxo-5-methylthiopentanoate aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102658 MetaCyc:RXN-2205 Catalysis of the reaction: 5-methylthio-2-oxopentanoate + a standard alpha amino acid <=> L-homomethionine + a 2-oxo carboxylate. GO:0004185 serine-type carboxypeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004185 EC:3.4.16.6|EC:3.4.16.5|EC:3.4.16.2|Reactome:R-HSA-158251|EC:3.4.16.-|MetaCyc:3.4.16.6-RXN|MetaCyc:3.4.16.5-RXN|MetaCyc:3.4.16.2-RXN serine carboxypeptidase activity Catalysis of the hydrolysis of a single C-terminal amino acid residue from the C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine). GO:0004184 obsolete lysine carboxypeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004184 CPase N|carboxypeptidase N activity|bradykinin-decomposing enzyme|peptidyl-L-lysine(-L-arginine) hydrolase|hippuryllysine hydrolase activity|anaphylatoxin inactivator activity|lysine(arginine) carboxypeptidase activity|kininase I activity|bradykinase activity|creatine kinase conversion factor|lysine (arginine) carboxypeptidase activity|creatinine kinase convertase activity|plasma carboxypeptidase B|lysine carboxypeptidase activity|kininase Ia|arginine carboxypeptidase activity OBSOLETE. Catalysis of the reaction: peptidyl-L-lysine (or peptidyl-L-arginine) + H2O = peptide + L-lysine (or L-arginine). Release of a C-terminal basic amino acid, preferentially lysine; inactivates bradykinin and anaphylatoxins in blood plasma. GO:0102657 1-18:1-2-16:0-monogalactosyldiacylglycerol palmitoyl-lipid 7-desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102657 EC:1.14.19.42|MetaCyc:RXN-1728 Catalysis of the reaction: 1-18:1-2-16:0-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor = 1-18:1-2-16:1-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. GO:0004190 aspartic-type endopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004190 EC:3.4.23.-|MetaCyc:3.4.23.5-RXN|MetaCyc:3.4.23.4-RXN|Reactome:R-HSA-2022403|MetaCyc:3.4.23.1-RXN|MetaCyc:3.4.23.15-RXN|MetaCyc:3.4.23.25-RXN|MetaCyc:3.4.23.36-RXN|MetaCyc:3.4.23.35-RXN|MetaCyc:3.4.23.34-RXN|Reactome:R-HSA-9013361|MetaCyc:3.4.23.43-RXN|EC:3.4.23.15|MetaCyc:3.4.23.32-RXN|MetaCyc:3.4.23.20-RXN|EC:3.4.23.25|EC:3.4.23.36|EC:3.4.23.35|EC:3.4.23.34|EC:3.4.23.43|EC:3.4.23.32|Reactome:R-HSA-2065357|EC:3.4.23.20|EC:3.4.23.5|EC:3.4.23.4|Reactome:R-HSA-2022412|Reactome:R-HSA-9017817|Reactome:R-HSA-157353|EC:3.4.23.1|Reactome:R-HSA-157640|Reactome:R-HSA-373705|Reactome:R-HSA-2220988|Reactome:R-HSA-9604294 carboxyl protease activity|aspartic endopeptidase activity|aspartic protease activity|aspartate protease activity|aspartyl protease activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile. GO:0102659 UDP-glucose: 4-methylthiobutylhydroximate S-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102659 MetaCyc:RXN-2208|EC:2.4.1.195 Catalysis of the reaction: UDP-alpha-D-glucose + 4-methylthiobutylhydroximate <=> H+ + 3-methylthiopropyl-desulfoglucosinolate + UDP. CHEBI:6877 trans-isomethyleugenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_6877 GO:0004192 obsolete cathepsin D activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004192 cathepsin D activity OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Specificity similar to, but narrower than, that of pepsin A. Does not cleave the Gln4-His5 bond in the B chain of insulin. GO:0004191 obsolete barrierpepsin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004191 Bar proteinase activity|extracellular 'barrier' protein activity|barrier proteinase activity|barrierpepsin activity OBSOLETE. Catalysis of the selected cleavage of the Leu6-Lys7 bond in the pheromone alpha-mating factor. GO:0102661 homogentisate solanyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102661 MetaCyc:RXN-2761|RHEA:37995|EC:2.5.1.117 Catalysis of the reaction: all-trans-nonaprenyl diphosphate + homogentisate + H+ <=> 2-methyl-6-all-trans-nonaprenyl-1,4-benzoquinone + carbon dioxide + diphosphoric acid. GO:0102660 caffeoyl-CoA:shikimate O-(hydroxycinnamoyl)transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102660 MetaCyc:RXN-2621 Catalysis of the reaction: caffeoylshikimate + coenzyme A <=> caffeoyl-CoA + shikimate. GO:0102663 gibberellin A34,2-oxoglutarate:oxygen oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102663 MetaCyc:RXN-292 Catalysis of the reaction: gibberellin A34 + 2-oxoglutarate + O2 <=> H+ + gibberellin A34-catabolite + succinate + carbon dioxide + H2O. GO:0004198 calcium-dependent cysteine-type endopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004198 Reactome:R-HSA-8863012|Reactome:R-HSA-8848658 calpain activity Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain by a mechanism using a cysteine residue at the enzyme active center, and requiring the presence of calcium. GO:0004197 cysteine-type endopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004197 Reactome:R-HSA-933532|Reactome:R-HSA-2130504|Reactome:R-HSA-2028692|Reactome:R-HSA-351876|Reactome:R-HSA-201595|Reactome:R-HSA-9647999|Reactome:R-HSA-418852|Reactome:R-HSA-351913|Reactome:R-HSA-211651|Reactome:R-HSA-202969|EC:3.4.22.-|Reactome:R-HSA-9012556|Reactome:R-HSA-1678920|Reactome:R-HSA-418845|Reactome:R-HSA-201634|Reactome:R-HSA-5634228|Reactome:R-HSA-2562564|Reactome:R-HSA-211190|Reactome:R-HSA-201639|Reactome:R-HSA-264871|Reactome:R-HSA-448703|Reactome:R-HSA-5357828|Reactome:R-HSA-202939|Reactome:R-HSA-264865|Reactome:R-HSA-202960|Reactome:R-HSA-114252|Reactome:R-HSA-9694551|MetaCyc:3.4.22.16-RXN|MetaCyc:3.4.22.27-RXN|MetaCyc:3.4.22.38-RXN|Reactome:R-HSA-1236948|Reactome:R-HSA-201636|MetaCyc:3.4.22.15-RXN|MetaCyc:3.4.22.14-RXN|MetaCyc:3.4.22.1-RXN|Reactome:R-HSA-9603534|Reactome:R-HSA-9686930|Reactome:R-HSA-5682377|Reactome:R-HSA-9697750|Reactome:R-HSA-201628|Reactome:R-HSA-2130336|Reactome:R-HSA-201637|EC:3.4.22.28|MetaCyc:3.4.22.34-RXN|EC:3.4.22.16|Reactome:R-HSA-114261|Reactome:R-HSA-202917|EC:3.4.22.27|EC:3.4.22.38|Reactome:R-HSA-9693929|EC:3.4.22.15|Reactome:R-HSA-351894|Reactome:R-HSA-351871|Reactome:R-HSA-201629|Reactome:R-HSA-202947|EC:3.4.22.14|Reactome:R-HSA-2130706|Reactome:R-HSA-9694441|Reactome:R-HSA-201640|MetaCyc:3.4.22.41-RXN|Reactome:R-HSA-211186|Reactome:R-HSA-9694625|Reactome:R-HSA-351877|Reactome:R-HSA-351901|Reactome:R-HSA-201603|MetaCyc:3.4.22.40-RXN|EC:3.4.22.34|Reactome:R-HSA-1678981|Reactome:R-HSA-9694732|Reactome:R-HSA-139952|Reactome:R-HSA-9684273|EC:3.4.22.8|Reactome:R-HSA-5681987|Reactome:R-HSA-9694601|Reactome:R-HSA-350318|EC:3.4.22.41|Reactome:R-HSA-9694338|EC:3.4.22.40|Reactome:R-HSA-3465448|Reactome:R-HSA-202967|Reactome:R-HSA-201608|Reactome:R-HSA-9684321|Reactome:R-HSA-9694377|Reactome:R-HSA-350158|Reactome:R-HSA-9684336|Reactome:R-HSA-201631|Reactome:R-HSA-139898|Reactome:R-HSA-2130349|Reactome:R-HSA-2028697|Reactome:R-HSA-9684340|Reactome:R-HSA-6814387|Reactome:R-HSA-201622|Reactome:R-HSA-418846|EC:3.4.22.1|Reactome:R-HSA-201630|Reactome:R-HSA-202966|Reactome:R-HSA-201611|Reactome:R-HSA-352268|Reactome:R-HSA-9684351|Reactome:R-HSA-350319|Reactome:R-HSA-351936|Reactome:R-HSA-9684309|Reactome:R-HSA-9684352|Reactome:R-HSA-351849|Reactome:R-HSA-5660663|Reactome:R-HSA-9013895|Reactome:R-HSA-212552|Reactome:R-HSA-350651|Reactome:R-HSA-114259 thiol endopeptidase activity|metacaspase activity|caspase activity|lysosomal cysteine-type endopeptidase Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile. GO:0102662 malonate-semialdehyde dehydrogenase (acetylating, NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102662 MetaCyc:RXN-2902|RHEA:22992 Catalysis of the reaction: 3-oxopropanoate + coenzyme A(4-) + NAD(1-) <=> acetyl-CoA(4-) + carbon dioxide + NADH(2-). GO:0102665 indole-3-acetyl-glutamate synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102665 MetaCyc:RXN-2947 Catalysis of the reaction: indole-3-acetate + L-glutamate + ATP <=> H+ + indole-3-acetyl-glutamate + AMP + diphosphoric acid. GO:0102664 indole-3-acetyl-leucine synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102664 MetaCyc:RXN-2945 Catalysis of the reaction: indole-3-acetate + L-leucine + ATP <=> H+ + indole-3-acetyl-leucine + diphosphoric acid + AMP. GO:0004199 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004199 GO:0004194 obsolete pepsin A activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004194 lactated pepsin elixir|P I|pepsin A activity|elixir lactate of pepsin|P II|pepsin R|pepsin activity|fundus-pepsin|lactated pepsin|pepsin D|pepsin fortior OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Preferential cleavage: hydrophobic, preferably aromatic, residues in P1 and P1' positions. Cleaves Phe1-Val2, Gln4-His5, Glu13-Ala14, Ala14-Leu15, Leu15-Tyr16, Tyr16-Leu17, Gly23-Phe24, Phe24-Phe25 and Phe25-Tyr26 bonds in the B chain of insulin. GO:0102667 indole-3-acetyl-beta-1-D-glucose hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102667 MetaCyc:RXN-3165 Catalysis of the reaction: 1-O-(indol-3-ylacetyl)-beta-D-glucose + H2O <=> H+ + indole-3-acetate + beta-D-glucose. GO:0004193 obsolete cathepsin E activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004193 cathepsin E activity|non-pepsin proteinase activity|erythrocyte membrane aspartic proteinase activity|slow-moving proteinase activity|cathepsin E-like acid proteinase activity|EMAP|cathepsin D-like acid proteinase activity|SMP|cathepsin D-type proteinase activity OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Similar to cathepsin D, but slightly broader specificity. GO:0102666 indole-3-acetyl-beta-4-D-glucose hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102666 MetaCyc:RXN-3164 Catalysis of the reaction: indole-3-acetyl-beta-4-D-glucose + H2O <=> H+ + indole-3-acetate + beta-D-glucose. GO:0004196 obsolete saccharopepsin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004196 Saccharomyces aspartic proteinase activity|aspartic proteinase yscA|saccharopepsin activity|PRA|saccharomyces aspartic proteinase activity|yeast proteinase A|yeast endopeptidase A activity|saccharomyces cerevisiae aspartic proteinase A|proteinase A|proteinase yscA OBSOLETE. Catalysis of the degradation of gelatin; little activity on hemoglobin. Specificity on B chain of insulin more restricted than pepsin A; does not cleave Phe1-Val2, Gln4-His5 or Gly23-Phe24. GO:0102669 isoflavone-7-O-glucoside beta-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102669 MetaCyc:RXN-3591 Catalysis of the reaction: daidzein 7-O-beta-D-glucoside + H2O <=> daidzein + beta-D-glucose. GO:0004195 obsolete renin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004195 renin activity|angiotensin-forming enzyme activity|angiotensinogenase activity OBSOLETE. Catalysis of the cleavage of Leu-Xaa bond in angiotensinogen to generate angiotensin I. GO:0102668 liquiritigenin,NADPH:oxygen oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102668 EC:1.14.14.87|RHEA:31723|MetaCyc:RXN-3283 Catalysis of the reaction: liquiritigenin + NADPH + O2 + H+ <=> 2,4',7-trihydroxyisoflavanone + NADP(3-) + H2O. CHEBI:6887 methylphenidate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_6887 CHEBI:138691 9-cis-retinyl tetradecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138691 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004169 EC:2.4.1.109|Reactome:R-HSA-5615604|Reactome:R-HSA-5615556|Reactome:R-HSA-5615637|MetaCyc:2.4.1.109-RXN O-glycoside mannosyltransferase|dolichyl-phosphate-D-mannose:protein O-D-mannosyltransferase activity|dolichyl-phosphate-mannose-protein O-mannosyltransferase activity|protein O-D-mannosyltransferase activity|dolichol phosphomannose-protein mannosyltransferase activity|protein O-mannosyltransferase activity Catalysis of the reaction: dolichyl phosphate D-mannose + protein = dolichyl phosphate + O-D-mannosylprotein. GO:0004168 dolichol kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004168 RHEA:13133|Reactome:R-HSA-4755600|MetaCyc:DOLICHOL-KINASE-RXN|EC:2.7.1.108|Reactome:R-HSA-446195 CTP:dolichol O-phosphotransferase activity|dolichol phosphokinase activity Catalysis of the reaction: CTP + dolichol = CDP + dolichyl phosphate. GO:0004165 dodecenoyl-CoA delta-isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004165 Reactome:R-HSA-109338|Reactome:R-HSA-6809808|MetaCyc:ENOYL-COA-DELTA-ISOM-RXN|RHEA:23716|EC:5.3.3.8 3,2-trans-enoyl-CoA isomerase activity|dodecenoyl-CoA isomerase activity|acetylene-allene isomerase activity|dodecenoyl-CoA Delta-isomerase activity|delta(3)-cis-Delta(2)-trans-enoyl-CoA isomerase activity|dodecenoyl-CoA (3Z)-(2E)-isomerase activity|delta3-cis-delta2-trans-enoyl-CoA isomerase|delta3,Delta2-enoyl-CoA isomerase activity|dodecenoyl-CoA D-isomerase activity|delta(3),Delta(2)-enoyl-CoA isomerase activity|dodecenoyl-CoA delta3-cis-delta2-trans-isomerase activity Catalysis of the reaction: 3-cis-dodecenoyl-CoA = 2-trans-dodecenoyl-CoA. GO:0004164 diphthine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004164 MetaCyc:RXN-11370|EC:2.1.1.98|RHEA:20145|Reactome:R-HSA-5358484 S-adenosyl-L-methionine:elongation factor 2 methyltransferase activity|diphthine methyltransferase activity|S-adenosyl-L-methionine:2-(3-carboxy-3-aminopropyl)-L-histidine methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 2-(3-carboxy-3-aminopropyl)-L-histidine = S-adenosyl-L-homocysteine + 2-(3-carboxy-3-(methylammonio)propyl)-L-histidine. GO:0004167 dopachrome isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004167 KEGG_REACTION:R03673|RHEA:13041|MetaCyc:DOPACHROME-DELTA-ISOMERASE-RXN|EC:5.3.3.12 DCF activity|dopachrome conversion activity|dopachrome delta7,Delta2-isomerase activity|dopachrome-rearranging enzyme|TRP2|tyrosinase-related protein 2 activity|dopachrome tautomerase activity|dopachrome keto-enol isomerase activity|TRP activity|L-dopachrome keto-enol isomerase activity|dopachrome rearranging enzyme activity|dopachrome conversion factor activity|DCT activity|L-dopachrome isomerase activity|TRP-2|dopachrome Delta(7),Delta(2)-isomerase activity|TRP-1|tryosinase-related protein-2|dopachrome oxidoreductase activity|dopachrome delta-isomerase activity|L-dopachrome-methyl ester tautomerase activity Catalysis of the reaction: L-dopachrome = 5,6-dihydroxyindole-2-carboxylate. GO:0004166 dolichyl-phosphate alpha-N-acetylglucosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004166 MetaCyc:2.4.1.153-RXN|RHEA:14693|EC:2.4.1.153 UDP-N-acetylglucosamine-dolichol phosphate N-acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:dolichyl-phosphate alpha-N-acetyl-D-glucosaminyltransferase activity|dolichyl-phosphate acetylglucosaminyltransferase activity|dolichyl-phosphate N-acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-dolichol phosphate acetylglucosaminyltransferase activity|dolichyl phosphate acetylglucosaminyltransferase activity|dolichyl phosphate N-acetylglucosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UDP + dolichyl N-acetyl-alpha-D-glucosaminyl phosphate. GO:0004161 dimethylallyltranstransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004161 EC:2.5.1.1|Reactome:R-HSA-191322|RHEA:22408|MetaCyc:GPPSYN-RXN (2E,6E)-farnesyl diphosphate synthetase activity|trans-farnesyl pyrophosphate synthetase activity|geranyl-diphosphate synthase activity|dimethylallyl-diphosphate:isopentenyl-diphosphate dimethylallyltranstransferase activity|geranyl pyrophosphate synthetase activity|DMAPP:IPP-dimethylallyltransferase activity|dimethylallyltransferase activity|diprenyltransferase activity|geranyl pyrophosphate synthase activity|geranyl diphosphate synthase Catalysis of the reaction: dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + geranyl diphosphate. GO:0004160 dihydroxy-acid dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004160 MetaCyc:DIHYDROXYISOVALDEHYDRAT-RXN|RHEA:20936|EC:4.2.1.9 alpha,beta-dihydroxyisovalerate dehydratase activity|2,3-dihydroxy-acid hydro-lyase (3-methyl-2-oxobutanoate-forming)|acetohydroxyacid dehydratase activity|2,3-dihydroxyisovalerate dehydratase activity|alpha,beta-dihydroxyacid dehydratase activity|2,3-dihydroxy-acid hydro-lyase activity|dihydroxy acid dehydrase activity|DHAD Catalysis of the reaction: 2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O. GO:0004163 diphosphomevalonate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004163 Reactome:R-HSA-191414|EC:4.1.1.33|RHEA:23732|MetaCyc:DIPHOSPHOMEVALONTE-DECARBOXYLASE-RXN|KEGG_REACTION:R01121 mevalonate-5-pyrophosphate decarboxylase activity|pyrophosphomevalonate decarboxylase activity|mevalonate pyrophosphate decarboxylase activity|mevalonate diphosphate decarboxylase activity|5-pyrophosphomevalonate decarboxylase activity|mevalonate 5-diphosphate decarboxylase activity|ATP:(R)-5-diphosphomevalonate carboxy-lyase (dehydrating)|pyrophosphomevalonic acid decarboxylase activity|ATP:(R)-5-diphosphomevalonate carboxy-lyase (adding ATP; isopentenyl-diphosphate-forming) Catalysis of the reaction: (R)-5-diphosphomevalonate + ATP = ADP + CO(2) + H(+) + isopentenyl diphosphate + phosphate. GO:0004162 dimethylnitrosamine demethylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004162 N-nitrosodimethylamine demethylase activity Catalysis of the removal of a methyl group from N-nitrosodimethylamine. GO:0004170 dUTP diphosphatase activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0004170 Reactome:R-HSA-73666|RHEA:10248|EC:3.6.1.23|KEGG_REACTION:R02100|MetaCyc:DUTP-PYROP-RXN desoxyuridine 5'-triphosphatase activity|dUTPase activity|dUTP nucleotidohydrolase activity|dUTP pyrophosphatase activity|desoxyuridine 5'-triphosphate nucleotidohydrolase activity|deoxyuridine-triphosphatase activity Catalysis of the reaction: dUTP + H2O = dUMP + diphosphate. CHEBI:138661 N-hexadecanoyl-O-(1-octadecanoyl-2-oleoyl-sn-glycero-3-phospho)-L-serine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138661 CHEBI:138660 dTDP-4-formamido-4,6-dideoxy-alpha-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138660 CHEBI:138664 N-(omega-hydroxytriacontanoyl)sphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138664 CHEBI:138663 N-hexadecanoyl-1-[(1Z)-octadecenoyl]-2-oleoyl-sn-glycero-3-phosphoethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138663 CHEBI:138662 N-hexadecanoyl-O-(1-octadecanoyl-sn-glycero-3-phospho)-L-serine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138662 GO:0004179 obsolete membrane alanyl aminopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004179 EC:3.4.11.2|MetaCyc:3.4.11.2-RXN membrane aminopeptidase I activity|alanyl aminopeptidase activity|cysteinylglycinase activity|L-alanine aminopeptidase activity|amino-oligopeptidase activity|membrane alanine aminopeptidase activity|microsomal aminopeptidase activity|particle-bound aminopeptidase activity|membrane alanyl aminopeptidase activity|aminopeptidase M activity|cysteinylglycine dipeptidase activity|aminopeptidase N activity|alanine-specific aminopeptidase activity|peptidase E activity|pseudo leucine aminopeptidase activity|CD13 OBSOLETE. Catalysis of the release of an N-terminal amino acid, Xaa-Xbb- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide. GO:0004176 ATP-dependent peptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004176 Reactome:R-HSA-9698929 ATP-dependent proteolysis Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the hydrolysis of peptide bonds. GO:0004175 endopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004175 Reactome:R-HSA-5358460|Reactome:R-HSA-5387392|Reactome:R-HSA-5668520|Reactome:R-HSA-1236970|Reactome:R-HSA-450466|Reactome:R-HSA-69016|Reactome:R-HSA-69600|Reactome:R-HSA-5693081|EC:3.4.99.-|Reactome:R-HSA-5668481|Reactome:R-HSA-68825|Reactome:R-HSA-9011313|Reactome:R-HSA-1168640|Reactome:R-HSA-174203|Reactome:R-HSA-180573|Reactome:R-HSA-5358340|Reactome:R-HSA-174255|Reactome:R-HSA-9614271|Reactome:R-HSA-5607731|Reactome:R-HSA-5687112|Reactome:R-HSA-74730|Reactome:R-HSA-4641256|Reactome:R-HSA-6784676|Reactome:R-HSA-8854044|Reactome:R-HSA-353125|Reactome:R-HSA-8850992|Reactome:R-HSA-8849797|Reactome:R-HSA-6784628|Reactome:R-HSA-4641260|Reactome:R-HSA-8866553|Reactome:R-HSA-9009362|Reactome:R-HSA-1251997|Reactome:R-HSA-5610758|Reactome:R-HSA-8854071|Reactome:R-HSA-174202|Reactome:R-HSA-187574|Reactome:R-HSA-8866858|MetaCyc:RXN0-5195|Reactome:R-HSA-3928656|Reactome:R-HSA-5658430|Reactome:R-HSA-5607724|Reactome:R-HSA-5635868|Reactome:R-HSA-5635854|Reactome:R-HSA-2130282|Reactome:R-HSA-983158|Reactome:R-HSA-8852354|Reactome:R-HSA-1234159|Reactome:R-HSA-180603|Reactome:R-HSA-8934819|Reactome:R-HSA-5362448|Reactome:R-HSA-983150|Reactome:R-HSA-8957265|Reactome:R-HSA-174058|Reactome:R-HSA-75825|Reactome:R-HSA-264458|Reactome:R-HSA-1433374|Reactome:R-HSA-68948|Reactome:R-HSA-5610754|Reactome:R-HSA-5610757|Reactome:R-HSA-211715|Reactome:R-HSA-209061|Reactome:R-HSA-188191|Reactome:R-HSA-8939801|Reactome:R-HSA-193682|Reactome:R-HSA-9010096|Reactome:R-HSA-2213200|Reactome:R-HSA-1236935|Reactome:R-HSA-1504193|Reactome:R-HSA-9604642|Reactome:R-HSA-9008475|Reactome:R-HSA-4608855|Reactome:R-HSA-3640874|Reactome:R-HSA-174105|Reactome:R-HSA-9008110|Reactome:R-HSA-5610760|Reactome:R-HSA-8952408 proteinase|proteasome endopeptidase activity|endoprotease activity|elastase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain. GO:0004178 obsolete leucyl aminopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004178 EC:3.4.11.1|MetaCyc:3.4.11.1-RXN leucinamide aminopeptidase activity|aminopeptidase II|FTBL proteins|cytosol aminopeptidase activity|leucyl peptidase activity|proteinates FTBL|leucyl aminopeptidase activity|peptidase S activity|leucine aminopeptidase activity|L-leucine aminopeptidase activity|cathepsin III|leucinaminopeptidase activity OBSOLETE. Catalysis of the release of an N-terminal amino acid, Xaa-Xbb-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Xbb may be Pro. GO:0004177 aminopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004177 MetaCyc:3.4.11.9-RXN|EC:3.4.11.-|MetaCyc:3.4.11.6-RXN|MetaCyc:3.4.11.5-RXN|MetaCyc:RXN0-5052|Reactome:R-HSA-1236954|MetaCyc:3.4.11.21-RXN|Reactome:R-HSA-2534096|EC:3.4.11.9|EC:3.4.11.21|EC:3.4.11.6|EC:3.4.11.5|Reactome:R-HSA-983162|Reactome:R-HSA-8851929 Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain. GO:0004172 obsolete ecdysteroid UDP-glucosyl/UDP-glucuronosyl transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004172 ecdysteroid UDP-glucosyl/UDP-glucuronosyl transferase activity OBSOLETE. (Was not defined before being made obsolete). GO:0102601 cytochrome P450 dependent beta-amyrin 16beta-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102601 RHEA:55440|MetaCyc:RXN-15385 Catalysis of the reaction: beta-amyrin + O2 + H+ + NAD(P)H <=> 16beta-hydroxy-beta-amyrin + H2O + NAD(P). GO:0102600 cytochrome P450 dependent 12,13beta-epoxy-beta-amyrin hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102600 MetaCyc:RXN-15384 Catalysis of the reaction: 12,13beta-epoxy-beta-amyrin + O2 + H+ + NAD(P)H <=> 12,13beta-epoxy-16beta-hydroxy-beta-amyrin + H2O + NAD(P). GO:0004171 obsolete deoxyhypusine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004171 deoxyhypusine synthase activity|[eIF-5A]-deoxyhypusine synthase OBSOLETE. Catalysis of the reaction: [eIF5A-precursor]-lysine + spermidine = [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine. GO:0004174 electron-transferring-flavoprotein dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004174 MetaCyc:1.5.5.1-RXN|Reactome:R-HSA-169270|EC:1.5.5.1|RHEA:24052 electron transfer flavoprotein reductase activity|ETF dehydrogenase activity|electron transfer flavoprotein-ubiquinone oxidoreductase activity|electron-transferring-flavoprotein:ubiquinone oxidoreductase activity|ETF:ubiquinone oxidoreductase activity|ETF-QO activity|electron transfer flavoprotein dehydrogenase activity|ETF-ubiquinone oxidoreductase activity|electron transfer flavoprotein Q oxidoreductase activity Catalysis of the reaction: a ubiquinone + reduced [electron-transfer flavoprotein] = a ubiquinol + H+ + oxidized [electron-transfer flavoprotein]. GO:0102603 12-demethyl-elloramycin C12a O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102603 MetaCyc:RXN-15402 Catalysis of the reaction: 12-demethyl-elloramycin + S-adenosyl-L-methionine <=> elloramycin + S-adenosyl-L-homocysteine + H+. GO:0102602 cytochrome P450 dependent 16beta-hydroxy-beta-amyrin epoxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102602 MetaCyc:RXN-15386 Catalysis of the reaction: 16beta-hydroxy-beta-amyrin + O2 + H+ + NAD(P)H <=> 12,13beta-epoxy-16beta-hydroxy-beta-amyrin + H2O + NAD(P). GO:0004173 ecdysone O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004173 RHEA:15217|KEGG_REACTION:R02375|EC:2.3.1.139|MetaCyc:ECDYSONE-O-ACYLTRANSFERASE-RXN palmitoyl-CoA:ecdysone palmitoyltransferase activity|fatty acyl-CoA:ecdysone acyltransferase activity|acyl-CoA:ecdysone acyltransferase activity Catalysis of the reaction: Ecdysone + palmitoyl-CoA = CoA + ecdysone palmitate. GO:0102605 cyclooctat-9-en-5,7-diol C18-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102605 RHEA:56824|MetaCyc:RXN-15430 Catalysis of the reaction: cyclooctat-9-en-5,7-diol + O2 + NADPH + H+ <=> cyclooctatin + H2O + NADP. GO:0102604 naringenin,NADPH:oxygen oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102604 RHEA:35487|MetaCyc:RXN-1541|EC:1.14.14.87 Catalysis of the reaction: (S)-naringenin(1-) + O2 + NADPH + H+ <=> 2-hydroxy-2,3-dihydrogenistein-7-olate + NADP + H2O. GO:0004181 metallocarboxypeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004181 MetaCyc:CARBOXYPEPTIDASE-B-RXN|EC:3.4.17.6|MetaCyc:CARBOXYPEPTIDASE-A-RXN|EC:3.4.17.4|EC:3.4.17.17|MetaCyc:3.4.17.22-RXN|EC:3.4.17.3|EC:3.4.17.2|Reactome:R-HSA-2022379|EC:3.4.17.1|Reactome:R-HSA-2022378|MetaCyc:GLY-X-CARBOXYPEPTIDASE-RXN|EC:3.4.17.22|EC:3.4.17.10|EC:3.4.17.21|MetaCyc:LYSINEARGININE-CARBOXYPEPTIDASE-RXN|EC:3.4.17.-|MetaCyc:ALANINE-CARBOXYPEPTIDASE-RXN|Reactome:R-HSA-9023159|Reactome:R-HSA-8866105|Reactome:R-HSA-9023163|MetaCyc:CARBOXYPEPTIDASE-H-RXN|MetaCyc:3.4.17.17-RXN|Reactome:R-HSA-8955712|Reactome:R-HSA-2028294|Reactome:R-HSA-8852809 Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. GO:0102607 3beta-hydroxy-12,15-cassadiene-11-one 2-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102607 MetaCyc:RXN-15433 Catalysis of the reaction: 3beta-hydroxy-12,15-cassadiene-11-one + NADPH + O2 + H+ <=> 2beta,3beta-dihydroxy-12,15-cassadiene-11-one + NADP + H2O. GO:0004180 carboxypeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004180 MetaCyc:3.4.17.11-RXN|EC:3.4.17.11|Reactome:R-HSA-1247910|RHEA:28783 Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain. GO:0102606 octat-9-en-7-ol 5-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102606 RHEA:56820|MetaCyc:RXN-15431 Catalysis of the reaction: cyclooctat-9-en-7-ol + O2 + NADPH + H+ <=> cyclooctat-9-en-5,7-diol + H2O + NADP. GO:0102609 9-beta-stemod-13(17)-ene oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102609 MetaCyc:RXN-15437|EC:1.14.13.144 Catalysis of the reaction: stemod-13(17)-ene + 3 NADPH + 3 O2 + 3 H+ <=> 9beta-stemod-13(17)-en-19-oate + 3 NADP + 4 H2O. GO:0102608 tetracenomycin B3 8-O-methyl transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102608 MetaCyc:RXN-15435 Catalysis of the reaction: tetracenomycin B3 + S-adenosyl-L-methionine <=> tetracenomycin E + S-adenosyl-L-homocysteine + H+. CHEBI:138676 11-cis-retinyl tetradecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138676 CHEBI:138675 gas molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138675 GO:0004147 dihydrolipoamide branched chain acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004147 dihydrolipoamide branched chain transacylase activity Catalysis of the reaction: acyl-CoA + dihydrolipoamide = CoA + S-acyldihydrolipoamide, where the acyl group is a branched chain. GO:0004146 dihydrofolate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004146 RHEA:15009|EC:1.5.1.3|Reactome:R-HSA-1497794|MetaCyc:DIHYDROFOLATEREDUCT-RXN dihydrofolic acid reductase activity|dihydrofolate reduction|7,8-dihydrofolate reductase activity|dihydrofolic reductase activity|pteridine reductase:dihydrofolate reductase activity|NADPH-dihydrofolate reductase activity|thymidylate synthetase-dihydrofolate reductase activity|folic reductase activity|5,6,7,8-tetrahydrofolate:NADP+ oxidoreductase activity|dihydrofolate reductase:thymidylate synthase activity|folic acid reductase activity|DHFR|tetrahydrofolate dehydrogenase activity Catalysis of the reaction: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH + H+. GO:0004149 dihydrolipoyllysine-residue succinyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004149 EC:2.3.1.61|RHEA:15213 lipoyl transsuccinylase activity|succinyl-CoA:dihydrolipoamide S-succinyltransferase activity|lipoate succinyltransferase activity|dihydrolipoamide succinyltransferase activity|enzyme-dihydrolipoyllysine:succinyl-CoA S-succinyltransferase activity|dihydrolipoamide S-succinyltransferase activity|dihydrolipoic transsuccinylase activity|succinyl-CoA:enzyme-N6-(dihydrolipoyl)lysine S-succinyltransferase activity|succinyl-CoA:dihydrolipoate S-succinyltransferase activity|dihydrolipoyl transsuccinylase activity|dihydrolipolyl transsuccinylase activity|succinyl-CoA:enzyme-6-N-(dihydrolipoyl)lysine S-succinyltransferase activity|lipoate succinyltransferase (Escherichia coli) activity|lipoic transsuccinylase activity Catalysis of the reaction: succinyl-CoA + dihydrolipoamide = CoA + S-succinyldihydrolipoamide. GO:0004148 dihydrolipoyl dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004148 MetaCyc:DIHYDLIPOXN-RXN|EC:1.8.1.4|Reactome:R-HSA-1222412|RHEA:15045|Reactome:R-HSA-5694018 E3 component of alpha-ketoacid dehydrogenase complexes activity|dihydrolipoamide reduction|glycine-cleavage system L-protein activity|lipoate dehydrogenase activity|dihydrolipoamide dehydrogenase activity|lipoamide reductase (NADH) activity|dihydrolipoic dehydrogenase activity|dihydrolipoylprotein reduction|lipoamide dehydrogenase (NADH) activity|dehydrolipoate dehydrogenase activity|lipoic acid dehydrogenase activity|lipoamide oxidoreductase (NADH) activity|dihydrolipoamide:NAD+ oxidoreductase|protein-N6-(dihydrolipoyl)lysine:NAD+ oxidoreductase|diaphorase activity|LDP-Glc activity|protein-6-N-(dihydrolipoyl)lysine:NAD+ oxidoreductase|lipoamide reductase activity|lipoyl dehydrogenase activity|LDP-Val activity|L-protein activity|dihydrothioctic dehydrogenase activity Catalysis of the reaction: protein N6-(dihydrolipoyl)lysine + NAD+ = protein N6-(lipoyl)lysine + NADH + H+. GO:0004143 diacylglycerol kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004143 EC:2.7.1.107|RHEA:10272|MetaCyc:DIACYLGLYKIN-RXN|Reactome:R-HSA-426240 diacylglycerol:ATP kinase activity|DGK activity|sn-1,2-diacylglycerol kinase activity|1,2-diacylglycerol kinase (phosphorylating)|CTP:diacylglycerol kinase activity|ATP:diacylglycerol phosphotransferase activity|ATP:1,2-diacylglycerol 3-phosphotransferase activity|diglyceride kinase activity|1,2-diacylglycerol kinase activity|arachidonoyl-specific diacylglycerol kinase activity|DG kinase activity Catalysis of the reaction: NTP + 1,2-diacylglycerol = NDP + 1,2-diacylglycerol-3-phosphate. GO:0004142 diacylglycerol cholinephosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004142 Reactome:R-HSA-1482973|RHEA:32939|MetaCyc:RXN-5781|EC:2.7.8.2|Reactome:R-HSA-1482961 phosphorylcholine--glyceride transferase activity|CDP-choline diglyceride phosphotransferase activity|sn-1,2-diacylglycerol cholinephosphotransferase activity|cytidine diphosphorylcholine diglyceride transferase activity|CPT|cholinephosphotransferase activity|alkylacylglycerol cholinephosphotransferase activity|alkylacylglycerol choline phosphotransferase activity|CDP-choline:1,2-diacylglycerol cholinephosphotransferase activity|1-alkyl-2-acetyl-m-glycerol:CDPcholine choline phosphotransferase activity|cytidine diphosphocholine glyceride transferase activity|phosphocholine diacylglyceroltransferase activity|1-alkyl-2-acetylglycerol cholinephosphotransferase activity|diacylglycerol choline phosphotransferase activity|1-alkyl-2-acetyl-sn-glycerol cholinephosphotransferase activity Catalysis of the reaction: CDP-choline + 1,2-diacylglycerol = CMP + a phosphatidylcholine. GO:0004145 diamine N-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004145 Reactome:R-HSA-351208|RHEA:25181|MetaCyc:DIAMACTRANS-RXN|Reactome:R-HSA-351207|EC:2.3.1.57 spermidine acetyltransferase activity|spermidine N(1)-acetyltransferase activity|acetyl-coenzyme A-1,4-diaminobutane N-acetyltransferase activity|spermine acetyltransferase|putrescine (diamine)-acetylating enzyme activity|putrescine acetyltransferase activity|putrescine N-acetyltransferase activity|spermine N-acetyltransferase|diamine acetyltransferase activity|spermidine/spermine N1-acetyltransferase activity|putrescine acetylase activity|acetyl-CoA:alkane-alpha,omega-diamine N-acetyltransferase activity|spermidine N1-acetyltransferase activity|spermine N(1)-acetyltransferase Catalysis of the reaction: acetyl-CoA + an alkane-alpha,omega-diamine = CoA + an N-acetyldiamine. GO:0102610 (+)-secoisolariciresinol glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102610 MetaCyc:RXN-15442 Catalysis of the reaction: (+)-secoisolariciresinol + UDP-alpha-D-glucose <=> (+)-secoisolariciresinol monoglucoside + UDP + H+. GO:0004144 diacylglycerol O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004144 MetaCyc:DIACYLGLYCEROL-O-ACYLTRANSFERASE-RXN|Reactome:R-HSA-1482889|Reactome:R-HSA-8848580|RHEA:10868|Reactome:R-HSA-75900|Reactome:R-HSA-549192|EC:2.3.1.20 diacylglycerol acyltransferase activity|palmitoyl-CoA-sn-1,2-diacylglycerol acyltransferase activity|acyl-CoA:1,2-diacylglycerol O-acyltransferase activity|1,2-diacylglycerol acyltransferase activity|diglyceride acyltransferase activity|diglyceride O-acyltransferase activity Catalysis of the reaction: acyl-CoA + 1,2-diacylglycerol = CoA + triacylglycerol. GO:0102612 syn-pimaradiene 6beta-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102612 MetaCyc:RXN-15452 Catalysis of the reaction: 9beta-pimara-7,15-diene + NADPH + O2 + H+ <=> 6beta-hydroxy-syn-pimaradiene + NADP + H2O. GO:0102611 (+)-secoisolariciresinol monoglucoside glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102611 MetaCyc:RXN-15443 Catalysis of the reaction: (+)-secoisolariciresinol monoglucoside + UDP-alpha-D-glucose <=> (+)-secoisolariciresinol diglucoside + UDP + H+. GO:0102614 germacrene A acid 8beta-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102614 MetaCyc:RXN-15460 Catalysis of the reaction: germacra-1(10),4,11(13)-trien-12-oate + NADPH + O2 + H+ <=> 8beta-hydroxy-germacra-1(10),4,11(13)-trien-12-oate + NADP + H2O. GO:0004141 dethiobiotin synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004141 EC:6.3.3.3|KEGG_REACTION:R03182|MetaCyc:DETHIOBIOTIN-SYN-RXN|RHEA:15805 DTB synthetase activity|desthiobiotin synthase activity|7,8-diaminononanoate:carbon-dioxide cyclo-ligase (ADP-forming) Catalysis of the reaction: 7,8-diaminononanoate + ATP + CO(2) = ADP + dethiobiotin + 4 H(+) + phosphate. GO:0004140 dephospho-CoA kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004140 KEGG_REACTION:R00130|RHEA:18245|MetaCyc:DEPHOSPHOCOAKIN-RXN|Reactome:R-HSA-196773|EC:2.7.1.24 dephosphocoenzyme A kinase (phosphorylating)|ATP:dephospho-CoA 3'-phosphotransferase activity|3'-dephospho-CoA kinase activity|dephosphocoenzyme A kinase activity Catalysis of the reaction: 3'-dephospho-CoA + ATP = ADP + CoA + 2 H(+). GO:0102613 trimethyluric acid monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102613 MetaCyc:RXN-15454|RHEA:48992 Catalysis of the reaction: 1,3,7-trimethyluric acid + O2 + NADH + 3 H+ <=> 1,3,7-trimethyl-5-hydroxyisourate + NAD + H2O. GO:0102616 oryzalexin A synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102616 MetaCyc:RXN-15464 Catalysis of the reaction: oryzalexin D + NAD(P) <=> oryzalexin A + H+ + NAD(P)H. GO:0102615 ent-cassadiene-C2-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102615 MetaCyc:RXN-15462|RHEA:55484 Catalysis of the reaction: ent-cassa-12,15-diene + NADPH + O2 + H+ <=> 2alpha-hydroxy-ent-cassadiene + NADP + H2O. GO:0102618 oryzalexin B synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102618 MetaCyc:RXN-15466 Catalysis of the reaction: oryzalexin D + NAD(P) <=> oryzalexin B + H+ + NAD(P)H. GO:0102617 oryzalexin C synthase (oryzalexin B dependent) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102617 MetaCyc:RXN-15465 Catalysis of the reaction: oryzalexin B + NAD(P) <=> oryzalexin C + H+ + NAD(P)H. GO:0018788 atrazine chlorohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018788 MetaCyc:3.8.1.8-RXN|UM-BBD_reactionID:r0113|EC:3.8.1.8|KEGG_REACTION:R05558|RHEA:11312 AtzA Catalysis of the reaction: atrazine + H(2)O = 4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine + chloride + H(+). GO:0102619 oryzalexin C synthase (oryzalexin A dependent) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102619 MetaCyc:RXN-15467 Catalysis of the reaction: oryzalexin A + NAD(P) <=> oryzalexin C + H+ + NAD(P)H. GO:0018787 4-chlorobenzoyl-CoA dehalogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018787 UM-BBD_enzymeID:e0113|MetaCyc:3.8.1.7-RXN|EC:3.8.1.7|RHEA:14853 4-chlorobenzoyl CoA chlorohydrolase activity Catalysis of the reaction: 4-chlorobenzoyl-CoA + H2O = 4-hydroxybenzoyl CoA + chloride. GO:0018789 cyclamate sulfohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018789 RHEA:18481|EC:3.10.1.2|MetaCyc:CYCLAMATE-SULFOHYDROLASE-RXN|UM-BBD_reactionID:r0755|KEGG_REACTION:R02564 cyclamate sulphohydrolase activity|cyclamate sulfamatase activity|cyclamate sulfamidase activity|cyclohexylsulfamate sulfohydrolase activity|cyclohexylsulfamate sulfamidase activity Catalysis of the reaction: cyclohexylsulfamate + H(2)O = cyclohexylamine + sulfate. GO:0018784 (S)-2-haloacid dehalogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018784 EC:3.8.1.2|UM-BBD_reactionID:r0090|RHEA:11192|MetaCyc:2-HALOACID-DEHALOGENASE-RXN (S)-2-haloacid halidohydrolase activity|2-haloalkanoid acid halidohydrolase activity|2-halocarboxylic acid dehalogenase II activity|DL-2-haloacid dehalogenase activity|2-haloacid halidohydrolase activity|L-2-haloacid dehalogenase activity|2-haloacid dehalogenase activity|halocarboxylic acid halidohydrolase activity|L-DEX activity|2-haloalkanoic acid dehalogenase activity Catalysis of the reaction: (S)-2-haloacid + H2O = (R)-2-hydroxyacid + halide. GO:0018783 deisopropyldeethylatrazine hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018783 Catalysis of the reaction: deisopropyldeethylatrazine + H2O = 2-chloro-4-hydroxy-6-amino-1,3,5-triazine + NH3. GO:0018786 haloalkane dehalogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018786 UM-BBD_enzymeID:e0003|EC:3.8.1.5|RHEA:25185|MetaCyc:HALOALKANE-DEHALOGENASE-RXN 1-chlorohexane halidohydrolase activity|1-haloalkane halidohydrolase activity|1-haloalkane dehalogenase activity Catalysis of the reaction: 1-haloalkane + H2O = a primary alcohol + halide. GO:0018785 haloacetate dehalogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018785 UM-BBD_enzymeID:e0006|MetaCyc:HALOACETATE-DEHALOGENASE-RXN|EC:3.8.1.3|RHEA:11044 haloacetate halidohydrolase activity|monohaloacetate dehalogenase activity Catalysis of the reaction: haloacetate + H2O = glycolate + halide. GO:0018780 dichloroacetate halidohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018780 UM-BBD_reactionID:r0383 Catalysis of the reaction: dichloroacetate + H2O = 2 HCl + glyoxylate. GO:0018782 cis-chloroacrylic acid dehalogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018782 UM-BBD_reactionID:r0688 Catalysis of the reaction: cis-3-chloroacrylic acid + H2O = H+ + HCl + malonate semialdehyde. GO:0018781 S-triazine hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018781 UM-BBD_enzymeID:e0091 Catalysis of the reaction: 1-halo or 1-pseudohalo-S-triazine = 1-hydroxy-S-triazine. CHEBI:138640 17(S)-HDoHE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138640 GO:0004158 dihydroorotate oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004158 RHEA:15441 (S)-dihydroorotate:oxygen oxidoreductase activity|4,5-L-dihydroorotate:oxygen oxidoreductase activity Catalysis of the reaction: (S)-dihydroorotate + O(2) = H(2)O(2) + orotate. GO:0004157 dihydropyrimidinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004157 Reactome:R-HSA-73589|MetaCyc:DIHYDROPYRIMIDINASE-RXN|Reactome:R-HSA-73618|EC:3.5.2.2|RHEA:16121 5,6-dihydropyrimidine amidohydrolase activity|hydropyrimidine hydrase activity|D-hydantoinase activity|hydantoin peptidase activity|pyrimidine hydrase activity|hydantoinase activity Catalysis of the reaction: 5,6-dihydrouracil + H2O = 3-ureidopropionate. GO:0004159 dihydrouracil dehydrogenase (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004159 RHEA:20189|MetaCyc:DIHYDROURACIL-DEHYDROGENASE-NAD+-RXN|EC:1.3.1.1 5,6-dihydrouracil:NAD+ oxidoreductase activity|uracil reductase activity|dehydrogenase, dihydrouracil|thymine reductase activity|pyrimidine reductase activity Catalysis of the reaction: 5,6-dihydrouracil + NAD+ = uracil + NADH + H+. GO:0004154 dihydropterin oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004154 EC:1.5.3.- Catalysis of the reaction: a 7,8-dihydropteridine + O2 = a pterin + hydrogen peroxide. GO:0004153 dihydropterin deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004153 Catalysis of the reaction: 7,8-dihydropterin + H2O = 7,8-dihydrolumazine + NH3. GO:0102621 emindole-SB NADPH:oxygen oxidoreductase (14,15-epoxidizing) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102621 MetaCyc:RXN-15496 Catalysis of the reaction: emindole-SB + O2 + NADPH + H+ <=> 14,15-epoxyemindole-SB + NADP + H2O. GO:0004156 dihydropteroate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004156 EC:2.5.1.15|RHEA:19949|MetaCyc:H2PTEROATESYNTH-RXN 7,8-dihydropteroate synthetase activity|(2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl-diphosphate:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase activity|dihydropteroic synthetase activity|7,8-dihydropteroate synthase activity|7,8-dihydropteroic acid synthetase activity|2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine-diphosphate:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase activity|dihydropteroate pyrophosphorylase activity|dihydropteroate diphosphorylase activity|DHPS activity|dihydropteroate synthetase activity Catalysis of the reaction: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + 4-aminobenzoate = diphosphate + dihydropteroate. GO:0004155 6,7-dihydropteridine reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004155 Reactome:R-HSA-71130|EC:1.5.1.34|MetaCyc:1.5.1.34-RXN NADPH-specific dihydropteridine reductase activity|5,6,7,8-tetrahydropteridine:NAD(P)+ oxidoreductase activity|dihydropteridine reduction|NADH-dihydropteridine reductase activity|NAD(P)H2:6,7-dihydropteridine oxidoreductase activity|6,7-dihydropteridine:NAD(P)H oxidoreductase activity|dihydropteridine reductase (NADH) activity|dihydropteridine reductase activity|dihydropteridine (reduced nicotinamide adenine dinucleotide) reductase activity|5,6,7,8-tetrahydropteridine:NAD(P)H+ oxidoreductase activity|DHPR activity|NAD(P)H(2):6,7-dihydropteridine oxidoreductase activity|NADPH-dihydropteridine reductase activity Catalysis of the reaction: NADP+ + 5,6,7,8-tetrahydropteridine = NADPH + H+ + 6,7-dihydropteridine. GO:0102620 3-geranylgeranylindole NADPH:oxygen oxidoreductase (10,11-epoxidizing) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102620 MetaCyc:RXN-15495 Catalysis of the reaction: 3-geranylgeranylindole + O2 + NADPH + H+ = 10,11-epoxy-3-geranylgeranylindole + NADP + H2O. GO:0004150 dihydroneopterin aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004150 EC:4.1.2.25|RHEA:10540|MetaCyc:H2NEOPTERINALDOL-RXN 2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-dihydropteridine glycolaldehyde-lyase activity|2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-dihydropteridine glycolaldehyde-lyase (2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine-forming) Catalysis of the reaction: 2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-dihydropteridine = 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + glycolaldehyde. GO:0102623 scutellarein 7-methyl ether 6-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102623 MetaCyc:RXN-15528 Catalysis of the reaction: scutellarein 7-methyl ether + S-adenosyl-L-methionine <=> cirsimaritin + S-adenosyl-L-homocysteine + H+. GO:0102622 linuron hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102622 MetaCyc:RXN-15526 Catalysis of the reaction: linuron + H2O <=> N,O-dimethylhydroxylamine + carbon dioxide + 3,4-dichloroaniline. GO:0004152 dihydroorotate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004152 Reactome:R-HSA-73569|KEGG_REACTION:R01868|MetaCyc:DIHYDROOROTATE-DEHYDROGENASE-RXN|EC:1.3.5.2|RHEA:18073 dihydoorotic acid dehydrogenase activity|dihydroorotate:ubiquinone oxidoreductase activity|(S)-dihydroorotate:quinone oxidoreductase activity|DHOdehase activity|(DHO) dehydrogenase activity Catalysis of the reaction: (S)-dihydroorotate + A = AH(2) + orotate. GO:0102625 cirsimaritin 4'-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102625 MetaCyc:RXN-15530 Catalysis of the reaction: cirsimaritin + S-adenosyl-L-methionine <=> salvigenin + S-adenosyl-L-homocysteine + H+. GO:0004151 dihydroorotase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004151 KEGG_REACTION:R01993|EC:3.5.2.3|RHEA:24296|Reactome:R-HSA-73571|MetaCyc:DIHYDROOROT-RXN (S)-dihydroorotate amidohydrolase activity|DHOase activity|dihydroorotate hydrolase activity|carbamoylaspartic dehydrase activity Catalysis of the reaction: (S)-dihydroorotate + H(2)O = N-carbamoyl-L-aspartate + H(+). GO:0102624 scutellarein 7-methyl ether 4'-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102624 MetaCyc:RXN-15529 Catalysis of the reaction: scutellarein 7-methyl ether + S-adenosyl-L-methionine <=> ladanein + S-adenosyl-L-homocysteine + H+. CHEBI:138658 dilinoleoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138658 GO:0102627 parthenolide 3beta-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102627 MetaCyc:RXN-15532 Catalysis of the reaction: parthenolide + NADPH + O2 + H+ <=> 3beta-hydroxyparthenolide + NADP + H2O. CHEBI:138657 6-(alpha-D-glucose-1-phospho)-alpha-D-mannoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138657 GO:0102626 parthenolide synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102626 MetaCyc:RXN-15531 Catalysis of the reaction: costunolide + NADPH + O2 + H+ <=> parthenolide + NADP(3-) + H2O. CHEBI:138656 rhizathalene A biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138656 GO:0102629 patuletin 3'-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102629 MetaCyc:RXN-15534 Catalysis of the reaction: patuletin + S-adenosyl-L-methionine <=> quercetagetin 3',6-dimethyl ether + S-adenosyl-L-homocysteine + H+. GO:0102628 costunolide 3beta-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102628 MetaCyc:RXN-15533 Catalysis of the reaction: costunolide + NADPH + O2 + H+ <=> 3beta-hydroxycostunolide + NADP + H2O. GO:0018799 4-hydroxybenzoate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018799 EC:4.1.1.61|UM-BBD_reactionID:r0159|RHEA:10876|KEGG_REACTION:R01238|MetaCyc:4-HYDROXYBENZOATE-DECARBOXYLASE-RXN 4-hydroxybenzoate carboxy-lyase activity|p-hydroxybenzoate decarboxylase activity|4-hydroxybenzoate carboxy-lyase (phenol-forming) Catalysis of the reaction: 4-hydroxybenzoate + H(+) = CO(2) + phenol. GO:0018798 gallate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018798 KEGG_REACTION:R03247|MetaCyc:GALLATE-DECARBOXYLASE-RXN|EC:4.1.1.59|RHEA:12749|UM-BBD_reactionID:r0005 gallic acid decarboxylase activity|gallate carboxy-lyase (pyrogallol-forming)|gallate carboxy-lyase activity Catalysis of the reaction: gallate + H(+) = CO(2) + pyrogallol. GO:0018795 2-hydroxy-2-methyl-1,3-dicarbonate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018795 UM-BBD_reactionID:r0621 Catalysis of the reaction: 2-hydroxy-2-methyl-1,3-dicarbonate + H+ = CO2 + L-lactate. GO:0018794 2-hydroxyisobutyrate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018794 UM-BBD_reactionID:r0617 Catalysis of the reaction: 2-hydroxyisobutyrate + H+ = CO2 + 2-propanol. GO:0018797 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018797 GO:0018796 4,5-dihydroxyphthalate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018796 RHEA:24184|MetaCyc:45-DIHYDROXYPHTHALATE-DECARBOXYLASE-RXN|UM-BBD_enzymeID:e0106|EC:4.1.1.55 4,5-dihydroxyphthalate carboxy-lyase (3,4-dihydroxybenzoate-forming)|4,5-dihydroxyphthalate carboxy-lyase activity Catalysis of the reaction: 4,5-dihydroxyphthalate = 3,4-dihydroxybenzoate + CO2. GO:0018791 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018791 UM-BBD_reactionID:r0398 Catalysis of the reaction: 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate = CO2 + 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate. CHEBI:138654 (R)-2-hydroxyhexadecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138654 GO:0018790 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018790 GO:0018793 3,5-dibromo-4-hydroxybenzoate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018793 UM-BBD_reactionID:r0546 Catalysis of the reaction: 3,5-dibromo-4-hydroxybenzoate + H+ = CO2 + 2,6-dibromophenol. CHEBI:138651 O-(S-fatty acylpantetheine-4'-phosphoryl)-L-serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138651 GO:0018792 bis(4-chlorophenyl)acetate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018792 UM-BBD_reactionID:r0520 DDA decarboxylase activity Catalysis of the reaction: bis(4-chlorophenyl)acetate + H+ = CO2 + bis(4-chlorophenyl)methane. Bis(4-chlorophenyl)acetate is also known as DDA; bis(4-chlorophenyl)methane is also known as DDM. UBERON:0005071 posterior neuropore biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005071 caudal neuropore The neuropore at the posterior (caudal) end of the neural tube. UBERON:0005070 anterior neuropore biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005070 rostral neuropore|cephalic neuropore|cranial neuropore The neuropore at the anterior (rostral) end of the neural tube. GO:0043731 6-hydroxynicotinate 3-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043731 MetaCyc:RXN-7573|RHEA:27333|EC:1.14.13.114 Catalysis of the oxidative decarboxylation of 6-hydroxynicotinate to 2,5-dihydroxypyridine, dependent on O2, NADH +H+ and FAD. GO:0043730 5-ureido-4-imidazole carboxylate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043730 Catalysis of the reaction: 5-ureido-4-imidazole carboxylate + H2O = 5-amino-4-imidazole carboxylate + NH3 + CO2. CHEBI:68588 germacrane sesquiterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68588 GO:0043737 deoxyribonuclease V activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043737 MetaCyc:3.1.21.7-RXN|EC:3.1.21.7 Escherichia coli endodeoxyribonuclease V activity|endodeoxyribonuclease V|endonuclease V activity|DNase V activity Catalysis of the endonucleolytic cleavage at apurinic or apyrimidinic sites to products with a 5'-phosphate. UBERON:0005079 eggshell biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005079 egg shell A product of the somatic follicle cell epithelium and a structure that supports the egg in a hostile environment, minimizing water loss whilst allowing gas exchanges essential for embryonic respiration[GO]. UBERON:0005078 lamina terminalis of neural tube biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005078 lamina terminalis The anterior-most (rostral) portion of the wall of the neural tube, formed by closure of the anterior neuropore; the median strip of the anterior wall of the prosencephalon, which persists in a relatively unchanged state as the cerebral hemispheres grow out forward beyond the original anterior end of the prosencephalon. GO:0043736 obsolete DNA-3-methyladenine glycosylase IV activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043736 DNA-3-methyladenine glycosylase IV activity|MpgII|Mpg II OBSOLETE. Catalysis of the hydrolysis of alkylated DNA; recognizes and removes both N-3- and N-7-methyl purines by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic (AP) site. GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043739 uracil mismatch repair protein|GU mismatch-specific uracil-DNA glycosylase activity|MUG Catalysis of the removal of uracil from a U*G mispair by the cleavage the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free uracil and leaves an apyrimidinic (AP) site. UBERON:0005077 neuropore biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005077 A temporary opening leading from the central canal of the embryonic neural tube to the exterior. GO:0043738 reduced coenzyme F420 dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043738 MetaCyc:RXN-8106|EC:1.5.98.3|RHEA:54752 F420H2 dehydrogenase activity|1,5-dihydrocoenzyme F420 dehydrogenase activity Catalysis of the reaction: methanophenazine + reduced coenzyme F420 = dihydromethanophenazine + coenzyme F420. UBERON:0005076 hindbrain-spinal cord boundary biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005076 hindbrain-spinal cord boundary region An anatomical boundary that adjacent_to a hindbrain and adjacent_to a spinal cord. UBERON:0005075 forebrain-midbrain boundary biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005075 forebrain midbrain boundary|forebrain-midbrain boundary region|diencephalic-mesencephalic boundary An anatomical boundary that adjacent_to a forebrain and adjacent_to a midbrain. GO:0043733 DNA-3-methylbase glycosylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043733 EC:3.2.2.- DNA-3-methyladenine glycosylase III|Mag III|MagIII Catalysis of the reaction: DNA containing 3-methylbase + H2O = DNA with abasic site + 3-methylbase. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methylpurine or 3-methylpyrimidine base and the deoxyribose sugar to remove the methylated base, leaving an apurinic or apyrimidinic site. GO:0043732 6-hydroxynicotinate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043732 RHEA:22808|MetaCyc:RXN-7585|EC:1.17.3.3|KEGG_REACTION:R07221 6-hydroxynicotinic acid dehydrogenase activity|6-hydroxynicotinic acid hydroxylase activity|6-hydroxynicotinate:O2 oxidoreductase activity|6-hydroxynicotinate hydroxylase activity Catalysis of the reaction: 6-hydroxynicotinate + H(2)O + O(2) = 2,6-dihydroxynicotinate + H(2)O(2). GO:0043735 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043735 GO:0043734 DNA-N1-methyladenine dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043734 Reactome:R-HSA-112118|Reactome:R-HSA-112123 AlkB|alpha-ketoglutarate-dependent dioxygenase Catalysis of the oxidative demethylation of N1-methyladenine and N3-methylcytosine in DNA, with concomitant decarboxylation of 2-oxoglutarate and releases oxidized methyl group on N1-methyladenine and N3-methylcytosine as formaldehyde. GO:0043740 GTP cyclohydrolase IIa activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043740 MetaCyc:RXN-10055|EC:3.5.4.29|RHEA:22468|KEGG_REACTION:R07306 GTP 8,9-hydrolase (phosphate-forming)|GTP 8,9-dihydrolase (phosphate-forming)|GTP cyclohydrolase III activity Catalysis of the reaction: GTP + 3 H(2)O = 2-amino-5-formylamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + 3 H(+) + 2 phosphate. GO:0043742 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043742 GO:0043741 alpha-aminoadipate acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043741 MetaCyc:RXN-5181 L-2-aminoadipate N-acetyltransferase activity Catalysis of the reaction: alpha-aminoadipate + acetyl-CoA = N2-acetyl-alpha-aminoadipate + coenzyme A. UBERON:0005068 neural rod biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005068 neural tube rod A solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts[GO]. An intermediate stage in the development of the central nervous system present during the segmentation period; the neural rod is roughly cylindrical in shape, forms from the neural keel, and is not yet hollowed out into the neural tube[ZFIN]. GO:0043748 O-succinylbenzoate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043748 EC:4.2.1.113 Catalysis of the reaction: 2-succinylbenzoate + H2O = 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate. UBERON:0005067 amphid sensory organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005067 amphid sensillum Amphid sensory organs are the sensory organs of nematodes[GO]. GO:0043747 N2-acetyl-L-lysine deacetylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043747 RHEA:28598|MetaCyc:RXN-5185 N-acetyl-lysine deacetylase activity Catalysis of the reaction: N2-acetyl-L-lysine + H2O = acetate + L-lysine. UBERON:0005066 right ventricular trabecular myocardium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005066 . GO:0043749 phenol, water dikinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043749 EC:2.7.9.- phenylphosphate synthase activity|phenol:water dikinase activity|ATP:phenol:water phosphotransferase activity Catalysis of the reaction: phenol + MgATP + H2O = phenylphosphate + MgAMP + orthophosphate. UBERON:0005065 right ventricular compact myocardium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005065 . GO:0043744 N2-acetyl-L-aminoadipate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043744 RHEA:41944|MetaCyc:RXN-5182 N-acetyl-L-aminoadipate 5-phosphotransferase activity|acetylaminoadipate kinase activity|N-acetylaminoadipate kinase activity|[LysW]-aminoadipate kinase Catalysis of the reaction: ATP + N-acetyl-L-2-aminoadipate = ADP + N-acetyl-L-2-aminoadipate 6-phosphate. UBERON:0005064 left ventricular trabecular myocardium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005064 . GO:0043743 LPPG:FO 2-phospho-L-lactate transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043743 RHEA:27510|EC:2.7.8.28 Catalysis of the reaction: 7,8-didemethyl-8-hydroxy-5-deazariboflavin + lactyl-2-diphospho-5'-guanosine = coenzyme F420-0 + GMP. UBERON:0005063 left ventricular compact myocardium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005063 . GO:0043746 N2-acetyl-L-lysine aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043746 N-acetyl-lysine aminotransferase activity Catalysis of the reaction: N2-acetyl-L-aminoadipate semialdehyde + L-glutamate = 2-oxoglutarate + N2-acetyl-L-lysine. UBERON:0005062 neural fold biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005062 medullary fold One of the two elevated edges of the neural groove[GO,MP]. GO:0043745 N2-acetyl-L-aminoadipate semialdehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043745 Catalysis of the reaction: N2-acetyl-L-aminoadipyl-delta-phosphate + NADPH + H+ = N2-acetyl-L-aminoadipate semialdehyde + NADP+ + orthophosphate. UBERON:0005061 neural groove biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005061 The median dorsal longitudinal groove formed in the embryo by the neural plate after the appearance of the neural folds. CHEBI:20612 5-methyltetrahydrofolate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20612 UBERON:0005069 neural fold hinge point biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005069 The median hinge point extends for the entire length of the neural tube, and the lateral hinge points do not form in the spinal cord region of the neural tube[GO]. GO:0043751 polyphosphate:AMP phosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043751 PPT|PAP Catalysis of the reaction: (polyphosphate)n + AMP = (polyphosphate)n-1 + ADP. GO:0043750 phosphatidylinositol alpha-mannosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043750 RHEA:47368|EC:2.4.1.345|MetaCyc:2.4.1.57-RXN GDPmannose:1-phosphatidyl-myo-inositol alpha-D-mannosyltransferase activity|guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase activity|phosphatidyl-myo-inositol alpha-mannosyltransferase activity|GDP mannose:1-phosphatidyl-myo-inositol alpha-D-mannosyltransferase activity|GDP-mannose:1-phosphatidyl-1D-myo-inositol alpha-D-mannosyltransferase activity|GDP mannose-phosphatidyl-myo-inositol alpha-mannosyltransferase activity Catalysis of the transfer of one or more alpha-D-mannose residues from GDP-mannose to positions 2,6 and others in 1-phosphatidyl-myo-inositol. GO:0043753 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043753 GO:0043752 adenosylcobinamide kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043752 MetaCyc:2.7.1.156-RXN|EC:2.7.1.156 AdoCbi kinase/AdoCbi-phosphate guanylyltransferase|RTP:adenosylcobinamide phosphotransferase activity|adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase|CobU Catalysis of the reaction: RTP + adenosylcobinamide = adenosylcobinamide phosphate + RDP (where RTP is either ATP or GTP). GO:0043759 methylbutanoate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043759 RHEA:46180 branched-chain acyl-CoA synthetase (ADP-forming) activity|branched chain acyl-CoA synthetase (ADP-forming) activity|branched-chain acyl CoA synthetase (ADP-forming) activity|branched chain acyl CoA synthetase (ADP-forming) activity Catalysis of the reaction: ATP + 2-methylbutanoate + CoA = AMP + diphosphate + 2-methylbutanoyl-CoA. UBERON:0005057 immune organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005057 immune system organ An organ that is part of a immune system [Automatically generated definition]. GO:0043758 acetate-CoA ligase (ADP-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043758 EC:6.2.1.13|RHEA:15081|MetaCyc:ACETATE--COA-LIGASE-ADP-FORMING-RXN acetyl coenzyme A synthetase (adenosine diphosphate-forming)|acetate thiokinase activity|acetate--CoA ligase (ADP-forming) activity|acetyl-CoA synthetase (ADP-forming) activity|acetate:CoA ligase (ADP-forming)|aryl-CoA synthetase (ADP-forming) activity Catalysis of the reaction: ATP + acetate + CoA = ADP + phosphate + acetyl-CoA. UBERON:0005056 external female genitalia biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005056 female external genitalia|external female genital organ|organa genitalia feminina externa|external genitalia of female reproductive system An external genitalia that is part of a female reproductive system [Automatically generated definition]. UBERON:0005055 zone of long bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005055 long bone zone An organ part that is part of a long bone [Automatically generated definition]. UBERON:0005054 primary dorsal nerve cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005054 dorsal nerve cord|true dorsal nerve cord A nerve cord in the dorsal mid-line that is the most prominent nerve cord. GO:0043755 alpha-ribazole phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043755 RHEA:24456|EC:3.1.3.73|KEGG_REACTION:R04594|MetaCyc:RIBAZOLEPHOSPHAT-RXN alpha-ribazole-5'-P phosphatase activity|alpha-ribazole-5'-phosphate phosphohydrolase activity|CobC Catalysis of the reaction: alpha-ribazole 5'-phosphate + H(2)O = alpha-ribazole + phosphate. UBERON:0005053 primary nerve cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005053 nerve cord|true nerve cord A cluster of neurons that is the most prominent longitudinally extending condensed part of a nervous system. GO:0043754 dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043754 RHEA:18865|MetaCyc:2.3.1.168-RXN|EC:2.3.1.168 2-methylpropanoyl-CoA:enzyme-N6-(dihydrolipoyl)lysine:S-(2-methylpropanoyl)transferase activity|enzyme-dihydrolipoyllysine:2-methylpropanoyl-CoA S-(2-methylpropanoyl)transferase activity|2-methylpropanoyl-CoA:enzyme-6-N-(dihydrolipoyl)lysine:S-(2-methylpropanoyl)transferase activity|dihydrolipoyl transacylase activity Catalysis of the reaction: 2-methylpropanoyl-CoA + enzyme N6-(dihydrolipoyl)lysine = CoA + enzyme N6-(S-[2-methylpropanoyl]dihydrolipoyl)lysine. UBERON:0005051 mediastinum testis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005051 body of highmore|testis mediastinum|hilum of testicle|mediastinum of testis The mediastinum testis is a network of fibrous connective tissue that extends from the upper to near the lower extremity of the testis, and is wider above than below. From its front and sides numerous imperfect septa (trabeculæ) are given off, which radiate toward the surface of the organ, and are attached to the tunica albuginea. They divide the interior of the organ into a number of incomplete spaces, called lobules. These are somewhat cone-shaped, being broad at their bases at the surface of the gland, and becoming narrower as they converge to the mediastinum. The mediastinum supports the rete testis and blood vessels of the testis in their passage to and from the substance of the gland[WP] GO:0043757 adenosylcobinamide-phosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043757 MetaCyc:RXN-6261|RHEA:21896|EC:6.3.1.10 CbiB|adenosylcobyric acid:(R)-1-aminopropan-2-yl phosphate ligase (ADP-forming)|AdoCbi-P synthase activity Catalysis of the reactions: ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate = ADP + phosphate + adenosylcobinamide phosphate, and ATP + adenosylcobyric acid + (R)-1-aminopropan-2-ol = ADP + phosphate + adenosylcobinamide. GO:0043756 adenosylcobinamide hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043756 RHEA:23504|MetaCyc:R346-RXN|KEGG_REACTION:R05226|EC:3.5.1.90 adenosylcobinamide amidohydrolase activity|CbiZ|AdoCbi amidohydrolase activity|AdoCbi hydrolase activity Catalysis of the reaction: adenosylcobinamide + H(2)O = (R)-1-aminopropan-2-ol + adenosylcobyrate. UBERON:0005058 hemolymphoid system gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005058 haemolymphoid system gland|hemopoietic or lymphoid gland|hemopoietic or lymphoid organ A gland that is part of a hemolymphoid system [Automatically generated definition]. GO:0043762 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043762 GO:0043761 archaetidylserine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043761 EC:2.7.8.38 CDP-2,3-di-O-geranylgeranyl-sn-glycerol:l-serine O-archaetidyltransferase activity|CDP-2,3-di-O-geranylgeranyl-sn-glycerol inositol 1-archaetidyltransferase activity Catalysis of the reaction: CDP-digeranylgeranylglycerol + L-serine = archaetidylserine + CMP. GO:0043764 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043764 GO:0043763 UTP:glucose-1-phosphate uridylyltransferase regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043763 glucose-1-phosphate uridylyltransferase regulator activity|UDP-glucose pyrophosphorylase regulator activity|UDP-glucose diphosphorylase regulator activity Modulates the activity of UTP:glucose-1-phosphate uridylyltransferase. GO:0043760 acetyldiaminopimelate aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043760 N-acetyl-diaminopimelate aminotransferase activity|N-acetyl-L,L-diaminopimelate aminotransferase activity Catalysis of the reaction: N-acetyl-L-2,6-diaminoheptanedioate + 2-oxoglutarate = N-acetyl-2-L-amino-6-oxoheptanedioate + L-glutamate. UBERON:0005046 mucosa of hard palate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005046 hard palate mucosa|organ mucosa of hard palate|hard palate mucous membrane|mucous membrane of hard palate A mucosa that is part of a hard palate [Automatically generated definition]. GO:0043769 Tpg-containing telomere binding complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043769 telomere complex A complex composed of four polypeptides, a telomere-protecting terminal protein (Tpg), a telomere-associated protein (Tap), DNA polymerase (PolA) and topoisomerase I (TopA), that functions in the replication of the telomeric regions of linear chromosomes, plasmids and circular replicons of some bacterial species. GO:0043766 Sep-tRNA:Cys-tRNA synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043766 EC:2.5.1.73|MetaCyc:RXN-10719|RHEA:25686 Sep-tRNA:Cys-tRNA synthetase activity|O-phosphoseryl-tRNA:cysteinyl-tRNA synthase activity|SepCysS Catalysis of the reaction: O-phospho-L-seryl-tRNACys + sulfide = L-cysteinyl-tRNACys + phosphate. UBERON:0005042 inner epithelial layer of tympanic membrane biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005042 mucous stratum of tympanic membrane|tympanic membrane external middle ear cavity epithelial component|tympanic membrane mucosa|mucosa of tympanic membrane|mucous layer of tympanic membrane A portion of the tympanic cavity epithelium which makes up the outer (cuticular) layer of the tympanic membrane GO:0043765 T/G mismatch-specific endonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043765 V.EcoKDcm|Vsr mismatch endonuclease|very short patch repair protein|DNA mismatch endonuclease Catalysis of the repair of T/G mismatches arising from deamination of 5-methylcytosine in DNA by nicking double-stranded DNA within the sequence CT(AT)GN or NT(AT)GG next to the mismatched thymidine residue. The incision is mismatch-dependent and strand-specific, in favor of the G-containing strand. The incision serves as a starting point for subsequent excision repair by DNA polymerase I, which excises thymidine and reinserts cytidine. CHEBI:19615 2-hydroxy-6-oxonona-2,4-dienedioate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_19615 GO:0043768 S-ribosylhomocysteine lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043768 KEGG_REACTION:R01291|MetaCyc:RIBOSYLHOMOCYSTEINASE-RXN|EC:4.4.1.21|RHEA:17753 ribosylhomocysteinase activity|LuxS|S-ribosylhomocysteinase activity|S-(5-deoxy-D-ribos-5-yl)-L-homocysteine homocysteine-lyase [(4S)-4,5-dihydroxypentan-2,3-dione-forming] Catalysis of the reaction: S-(5-deoxy-D-ribos-5-yl)-L-homocysteine = (S)-4,5-dihydroxypentane-2,3-dione + L-homocysteine. UBERON:0005040 mucosa of terminal bronchiole biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005040 organ mucosa of bronchiolus terminalis|mucous membrane of terminal bronchiole|bronchiolus terminalis mucosa|terminal bronchiole mucosa|mucosa of organ of terminal bronchiole|mucosa of organ of bronchiolus terminalis|mucosa of bronchiolus terminalis|mucous membrane of bronchiolus terminalis|terminal bronchiole mucosa of organ|organ mucosa of terminal bronchiole|bronchiolus terminalis mucosa of organ|bronchiolus terminalis organ mucosa|terminal bronchiole organ mucosa|terminal bronchiole mucous membrane|bronchiolus terminalis mucous membrane A mucosa that is part of a terminal bronchiole [Automatically generated definition]. GO:0043767 pyrrolysyl-tRNA synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043767 MetaCyc:6.1.1.26-RXN|RHEA:19277|EC:6.1.1.26 PylRS|pyrrolysine-tRNA ligase activity Catalysis of the reaction: ATP + L-pyrrolysine + tRNA(Pyl) = AMP + diphosphate + L-pyrrolysyl-tRNA(Pyl). UBERON:0005049 mucosa of infundibulum of uterine tube biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005049 mucous membrane of uterine tube infundibulum|mucosa of uterine tube infundibulum|mucosa of organ of uterine tube infundibulum|mucosa of infundibulum of fallopian tube|uterine tube infundibulum organ mucosa|organ mucosa of uterine tube infundibulum|uterine tube infundibulum mucosa of organ|uterine tube infundibulum mucous membrane|uterine tube infundibulum mucosa|mucosa of infundibulum of oviduct A mucosa that is part of a uterine tube infundibulum [Automatically generated definition]. UBERON:0005048 mucosa of uterine tube biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005048 fallopian tube mucosa|uterine tube mucosa of organ|mucosa of fallopian tube|mucous membrane of fallopian tube|uterine tube mucosa|uterine tube mucous membrane|fallopian tube mucosa of organ|fallopian tube mucous membrane|organ mucosa of uterine tube|tunica mucosa tubae uterinae|fallopian tube organ mucosa|organ mucosa of fallopian tube|uterine tubal mucosa|uterine tube organ mucosa|mucosa of organ of uterine tube|mucous membrane of uterine tube|mucosa of organ of fallopian tube|mucosa of oviduct A mucosa that is part of a fallopian tube [Automatically generated definition]. GO:0102670 2,7,4'-trihydroxyisoflavanone-4'-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102670 RHEA:31371|EC:2.1.1.212|MetaCyc:RXN-3624 Catalysis of the reaction: 2,4',7-trihydroxyisoflavanone + S-adenosyl-L-methionine <=> H+ + 2,7-dihydroxy-4'-methoxyisoflavanone + S-adenosyl-L-homocysteine. GO:0102672 fatty acid alpha-oxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102672 MetaCyc:RXN-4121 Catalysis of the reaction: O2 + a 2,3,4-saturated fatty acid <=> a 2(R)-hydroperoxy fatty acid. GO:0102671 6a-hydroxymaackiain-3-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102671 MetaCyc:RXN-4002|RHEA:35471|EC:2.1.1.270 Catalysis of the reaction: (+)-6a-hydroxymaackiain + S-adenosyl-L-methionine <=> H+ + (+)-pisatin + S-adenosyl-L-homocysteine. GO:0102674 C4-demethylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102674 MetaCyc:RXN-4181 Catalysis of the reaction: 24-methylenelophenol + a demethylated methyl acceptor <=> 9xi-episterol + a methylated methyl acceptor. GO:0043773 coenzyme F420-0 gamma-glutamyl ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043773 F420-0 gamma-glutamyl ligase activity Catalysis of the reactions: (1) GTP + F420-0 + L-glutamate = GDP + phosphate + F420-1, and (2) GTP + F420-1 + L-glutamate = GDP + phosphate + gamma-F420-2. This is the GTP-dependent successive addition of two L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form F420-0-glutamyl-glutamate (F420-2), with a gamma-linkage between the two glutamates. GO:0102673 fatty aldehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102673 MetaCyc:RXN-4142 Catalysis of the reaction: NAD(1-) + H2O + a fatty aldehyde <=> NADH(2-) + 2 H+ + a fatty acid. GO:0043772 acyl-phosphate glycerol-3-phosphate acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043772 acylphosphate:glycerol-3-phosphate acyltransferase activity|acyl-phosphate:glycerol-3-phosphate acyltransferase activity|acylphosphate glycerol-3-phosphate acyltransferase activity Catalysis of the reaction: acyl phosphate + sn-glycerol 3-phosphate = 1-acyl-sn-glycerol 3-phosphate + orthophosphate. GO:0043775 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043775 GO:0102676 avenasterol-desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102676 MetaCyc:RXN-4209 Catalysis of the reaction: avenasterol + O2 + NADPH + H+ <=> 5-dehydroavenasterol + 2 H2O + NADP. GO:0043774 coenzyme F420-2 alpha-glutamyl ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043774 RHEA:42332|EC:6.3.2.32 F420-2 alpha-glutamyl ligase activity Catalysis of the reaction: coenzyme F420-2 + L-glutamate + GTP = coenzyme F420-3 + GDP + orthophosphate. GO:0102675 C4-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102675 MetaCyc:RXN-4208 Catalysis of the reaction: 24-ethylidenelophenol + a demethylated methyl acceptor <=> avenasterol + a methylated methyl acceptor. GO:0102678 22-alpha-hydroxy-campest-4-en-3-one,NADPH:steroid 5alpha-reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102678 MetaCyc:RXN-4229 Catalysis of the reaction: (5alpha,22S,24R)-22-hydroxyergostan-3-one + NADP <=> H+ + (22S)-22-hydroxycampest-4-en-3-one + NADPH. GO:0102677 campesterol,NADPH:oxygen oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102677 MetaCyc:RXN-4225 Catalysis of the reaction: H+ + campesterol + O2 + NADPH <=> (22S)-22-hydroxycampesterol + H2O + NADP. GO:0043771 cytidine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043771 Catalysis of the reaction: ATP + cytidine = ADP + CMP. GO:0043770 demethylmenaquinone methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043770 EC:2.1.1.163 Catalysis of the reaction: 2-demethylmenaquinone + S-adenosyl-L-methionine = menaquinone + S-adenosyl-L-homocysteine. GO:0102679 (5alpha)-campestan-3-one hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102679 MetaCyc:RXN-4230 Catalysis of the reaction: H+ + (5alpha)-campestan-3-one + O2 + NADPH <=> (5alpha,22S,24R)-22-hydroxyergostan-3-one + H2O + NADP. GO:0043777 cobalt-precorrin-7 C15-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043777 RHEA:34591|MetaCyc:RXN-8767 precorrin-6Y methylase|cobalt-precorrin 7 C15-methyltransferase activity|precorrin-6 methyltransferase|precorrin-6Y C5,15-methyltransferase (decarboxylating) Catalysis of the reaction: cobalt-precorrin 7 + S-adenosyl-L-methionine = cobalt-precorrin 8 + S-adenosyl-L-homocysteine + CO2. GO:0043776 cobalt-precorrin-6B C5-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043776 RHEA:36067|MetaCyc:RXN-8766 cobalt-precorrin 6B C5-methyltransferase activity|precorrin-6 methyltransferase activity|precorrin-6Y methylase|precorrin-6Y C5,15-methyltransferase (decarboxylating) Catalysis of the reaction: S-adenosylmethionine + cobalt-precorrin 6B = S-adenosylhomocysteine + cobalt-precorrin 7. GO:0043779 cobalt-precorrin-5A acetaldehyde-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043779 MetaCyc:RXN-8763|RHEA:26281 cobalt-precorrin 5A acetaldehyde-lyase activity Catalysis of the reaction: cobalt-precorrin 5A + H2O = cobalt-precorrin 5B + acetaldehyde. GO:0043778 cobalt-precorrin-8 methylmutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043778 RHEA:16209|EC:5.4.99.60|MetaCyc:RXN-8768 cobalt-precorrin 8X methylmutase activity|cobalt-precorrin-8X methylmutase activity|cobalt-precorrin 8 methylmutase activity Catalysis of the reaction: cobalt-precorrin 8 = cobyrinate. GO:0102681 isoamylase (maltodextrin-releasing) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102681 MetaCyc:RXN-4301 Catalysis of the reaction: n H2O + a glycogen <=> n a maltodextrin. GO:0102680 campest-4-en-3-one hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102680 MetaCyc:RXN-4231 Catalysis of the reaction: H+ + campest-4-en-3-one + O2 + NADPH <=> (22S)-22-hydroxycampest-4-en-3-one + H2O + NADP. GO:0102682 N6-(Delta2-isopentenyl)-adenosine 5'-monophosphate phosphoribohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102682 RHEA:48560|MetaCyc:RXN-4313 Catalysis of the reaction: N(6)-(dimethylallyl)adenosine 5'-phosphate + H2O <=> N(6)-dimethylallyladenine + D-ribofuranose 5-phosphate. GO:0102685 UDP-glucose:trans-zeatin 7-N-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102685 MetaCyc:RXN-4721 Catalysis of the reaction: UDP-alpha-D-glucose + trans-zeatin <=> H+ + trans-zeatin-7-N-glucoside + UDP. GO:0043784 cob(II)yrinic acid a,c-diamide reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043784 KEGG_REACTION:R05218|MetaCyc:R343-RXN|EC:1.16.8.1|RHEA:24300 cob(II)yrinic acid-a,c-diamide:FMN oxidoreductase activity Catalysis of the reaction: 2 cob(I)yrinate a,c diamide + FMN + 3 H(+) = 2 cob(II)yrinate a,c diamide + FMNH(2). GO:0102684 L-phenylalanine N-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102684 MetaCyc:RXN-4602|EC:1.14.14.40|RHEA:33263 Catalysis of the reaction: L-phenylalanine + 2 NADPH + 2 O2 + 2 H+ <=> (E)-phenylacetaldehyde oxime + 2 NADP + 3 H2O + carbon dioxide. GO:0043783 oxidoreductase activity, acting on metal ions, flavin as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043783 EC:1.16.8.- oxidoreductase activity, reducing metal ions, flavin as acceptor|oxidoreductase activity, oxidizing metal ions with flavin as acceptor Catalysis of an oxidation-reduction in which the metal ion is reduced and flavin acts as an electron acceptor. GO:0043786 cinnamate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043786 EC:1.3.1.- Catalysis of the reaction: 3-phenylpropanoate + NAD+ = (E)-cinnamate + NADH + H+. GO:0102687 UDP-glucose:dihydrozeatin 7-N-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102687 MetaCyc:RXN-4724 Catalysis of the reaction: UDP-alpha-D-glucose + dihydrozeatin <=> H+ + dihydrozeatin-7-N-glucose + UDP. GO:0102686 UDP-glucose:trans-zeatin 9-N-glucosyltransferase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102686 MetaCyc:RXN-4722 Catalysis of the reaction: UDP-alpha-D-glucose(2-) + trans-zeatin <=> H+ + 9-(alpha-D-glucosyl)-trans-zeatin + UDP(3-). GO:0043785 cinnamoyl-CoA:phenyllactate CoA-transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043785 MetaCyc:2.8.3.17-RXN|EC:2.8.3.17|RHEA:15601|KEGG_REACTION:R07796 FldA|(E)-cinnamoyl-CoA:(R)-phenyllactate CoA-transferase activity Catalysis of the reaction: (R)-3-phenyllactate + [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonatooxy)oxolan-2-yl]methyl {[(3R)-3-hydroxy-2,2-dimethyl-3-({2-[(2-{[(2E)-3-phenylprop-2-enoyl]sulfanyl}ethyl)carbamoyl]ethyl}carbamoyl)propyl phosphonato]oxy}phosphonate = (R)-3-phenyllactoyl-CoA + trans-cinnamate. GO:0102689 UDP-glucose:isopentenyladenine 7-N-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102689 MetaCyc:RXN-4727 Catalysis of the reaction: UDP-alpha-D-glucose + N(6)-dimethylallyladenine <=> H+ + 7-(alpha-D-glucosyl)-N(6)-isopentenyladenine + UDP. GO:0043780 cobalt-precorrin-5B C1-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043780 MetaCyc:RXN-8764|RHEA:26285 cobalt-precorrin 5B C1-methyltransferase activity Catalysis of the reaction: cobalt-precorrin 5B + S-adenosylmethionine = S-adenosylhomocysteine + cobalt-precorrin 6A. GO:0102688 dihydrozeatin UDP glycosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102688 MetaCyc:RXN-4725 Catalysis of the reaction: UDP-alpha-D-glucose + dihydrozeatin <=> H+ + 9-(alpha-D-glucosyl)dihydrozeatin + UDP. GO:0043782 cobalt-precorrin-3 C17-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043782 MetaCyc:RXN-8761|RHEA:26273 cobalt-precorrin-3 methyltransferase|cobalt-precorrin 3 C17-methyltransferase activity|cobalt-precorrin-3 methylase|cobalt-precorrin-3B C17-methyltransferase activity Catalysis of the reaction: cobalt-precorrin 3 + S-adenosyl-L-methionine = cobalt-precorrin 4 + S-adenosyl-L-homocysteine. GO:0043781 cobalt-factor II C20-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043781 EC:2.1.1.151|MetaCyc:RXN-8760|RHEA:17997 cobalt-precorrin-2 C(20)-methyltransferase activity|S-adenosyl-L-methionine:cobalt-factor-II C20-methyltransferase activity|cobalt-factor II C20 methyltransferase activity|CbiL Catalysis of the reaction: S-adenosyl-L-methionine + cobalt-factor II = S-adenosyl-L-homocysteine + cobalt-factor III. GO:0043788 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043788 GO:0043787 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043787 GO:0043789 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043789 NCBITaxon:7742 Vertebrata organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_7742 Vertebrata|vertebrates|vertebrates GO:0102690 isopentenyladenine UDP glycosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102690 MetaCyc:RXN-4728 Catalysis of the reaction: UDP-alpha-D-glucose + N(6)-dimethylallyladenine = H+ + 9-(alpha-D-glucosyl)-N(6)-isopentenyladenine + UDP. GO:0102692 benzyladenine UDP glycosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102692 MetaCyc:RXN-4730 Catalysis of the reaction: UDP-alpha-D-glucose + N-benzyladenine <=> H+ + N-benzyl-9-(alpha-D-glucosyl)adenine + UDP. GO:0102691 UDP-glucose:benzyladenine 7-N-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102691 MetaCyc:RXN-4729 Catalysis of the reaction: UDP-alpha-D-glucose + N-benzyladenine <=> H+ + benzyladenine-7-N-glucoside + UDP. GO:0102694 kinetin UDP glycosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102694 MetaCyc:RXN-4732 Catalysis of the reaction: UDP-alpha-D-glucose + kinetin <=> H+ + 9-(alpha-D-glucosyl)kinetin + UDP. GO:0102693 UDP-glucose:kinetin 7-N-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102693 MetaCyc:RXN-4731 Catalysis of the reaction: UDP-alpha-D-glucose + kinetin <=> H+ + kinetin-7-N-glucoside + UDP. UBERON:0005093 embryonic cement gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005093 cement gland A simple mucus-secreting structure that is positioned at the front of the embryo, attaches the newly hatched embryo to a support before the hatchling can swim well or feed, and marks the anterior-most dorsal ectoderm[XAO]. GO:0043795 glyceraldehyde oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043795 RHEA:36047|EC:1.2.99.8 Catalysis of the reaction: A + D-glyceraldehyde + H2O = (R)-glycerate + AH2 + H(+). GO:0102696 cis-zeatin UDP glycosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102696 MetaCyc:RXN-4734 Catalysis of the reaction: UDP-alpha-D-glucose + cis-zeatin = H+ + 9-(alpha-D-glucosyl)-cis-zeatin + UDP. GO:0043794 formate dehydrogenase (coenzyme F420) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043794 EC:1.2.99.- formate dehydrogenase (F420) activity Catalysis of the reaction: formate + coenzyme F420 = CO2 + reduced coenzyme F420. UBERON:0005092 right horn of sinus venosus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005092 sinus venosus right horn GO:0102695 UDP-glucose:cis-zeatin 7-N-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102695 MetaCyc:RXN-4733 Catalysis of the reaction: UDP-alpha-D-glucose + cis-zeatin <=> H+ + cis-zeatin-7-N-glucoside + UDP. GO:0043797 glyceraldehyde-3-phosphate dehydrogenase (ferredoxin) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043797 MetaCyc:1.2.7.6-RXN|RHEA:24148|EC:1.2.7.6 glyceraldehyde-3-phosphate Fd oxidoreductase activity|D-glyceraldehyde-3-phosphate:ferredoxin oxidoreductase activity|glyceraldehyde-3-phosphate ferredoxin reductase activity|GAPOR Catalysis of the reaction: D-glyceraldehyde-3-phosphate + H2O + 2 oxidized ferredoxin = 3-phospho-D-glycerate + 2 H+ + 2 reduced ferredoxin. GO:0102698 5-epi-aristolochene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102698 MetaCyc:RXN-4781|RHEA:28635|EC:4.2.3.61 Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (+)-5-epi-aristolochene + diphosphoric acid. UBERON:0005091 left horn of sinus venosus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005091 sinus venosus left horn GO:0043796 glyceraldehyde dehydrogenase (NADP) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043796 RHEA:40163|EC:1.2.1.89 Catalysis of the reaction: D-glyceraldehyde + H2O + NADP+ = D-glycerate + NADPH + H+. GO:0102697 trans-zeatin-O-glucoside UDP glycosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102697 MetaCyc:RXN-4736 Catalysis of the reaction: UDP-alpha-D-glucose + O-beta-D-glucosyl-trans-zeatin = H+ + trans-zeatin-O-glucoside-7-N-glucoside + UDP. UBERON:0005090 muscle structure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005090 musculus|muscle|muscle element Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms[GO]. GO:0043791 dimethylamine methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043791 RHEA:41175|EC:2.1.1.249|MetaCyc:RXN-8100 mtbB1|MT1|dimethylamine-specific methylcobalamin:coenzyme M methyltransferase activity|dimethylamine:corrinoid methyltransferase activity|DMA methyltransferase 1|DMAMT 1 Catalysis of the reaction: dimethylamine + a dimethylamine corrinoid protein = a methylated dimethylamine corrinoid protein + methylamine. GO:0043790 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043790 GO:0102699 2-methylpropionitrile hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102699 RHEA:51964|MetaCyc:RXN-5082 Catalysis of the reaction: H+ + 2-methylpropionitrile + O2 + NADPH <=> 2-hydroxy-2-methylpropanenitrile + NADP + H2O. GO:0043793 beta-ribofuranosylaminobenzene 5'-phosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043793 MetaCyc:RXN-8124 beta-RFAP synthase activity Catalysis of the reaction: 4-aminobenzoate + 5-phospho-alpha-D-ribose 1-diphosphate = 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + CO2 + diphosphate. OBO:GOCHE_35610 substance with antineoplastic agent role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_35610 GO:0043792 enamidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043792 RHEA:17209|KEGG_REACTION:R07984|MetaCyc:3.5.2.18-RXN|EC:3.5.2.18 6-oxo-1,4,5,6-tetrahydronicotinate amidohydrolase activity Catalysis of the reaction: 1,4,5,6-tetrahydro-6-oxonicotinate + 2 H(2)O = 2-formylglutarate + NH(4)(+). PR:000030443 polyubiquitin-B biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000030443 UBB A polyubiquitin that is a translation product of the human UBB gene or a 1:1 ortholog thereof. UBERON:0005099 short descending thin limb biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005099 The short descending thin limb is the descending thin limb of a short nephron that has a squamous epithelial morphology[GO]. GO:0043799 glycine oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043799 MetaCyc:RXN-8673|MetaCyc:RXN-8672|MetaCyc:1.4.3.19-RXN|EC:1.4.3.19|MetaCyc:RXN-8674 glycine:oxygen oxidoreductase (deaminating) Catalysis of the reactions: (1) glycine + H2O + O2 = glyoxylate + NH3 + hydrogen peroxide; (2) D-alanine + H2O + O2 = pyruvate + NH3 + hydrogen peroxide; (3) sarcosine + H2O + O2 = glyoxylate + methylamine + hydrogen peroxide; (4) N-ethylglycine + H2O + O2 = glyoxylate + ethylamine + hydrogen peroxide. UBERON:0005097 renal connecting tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005097 connecting tubule|kidney connecting tubule|tubulus renalis arcuatus The connecting tubule is a tubular segment of the nephron; it connects the distal convoluted tubule to the collecting duct[GO]. UBERON:0005096 descending thin limb biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005096 thin descending limb of loop of Henle|thin descending loop of Henle|loop of Henle thin descending limb|descending limb of loop of Henle|loop of Henle descending thin limb|thin descending limb|thin descending limb of the loop of Henle|pars descendens (tubulus attenuatus)|descending limb of Henle's loop|descending thin limb of loop of Henle The descending thin limb is a part of the loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the loop of Henle[GO]. GO:0043798 glycerate 2-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043798 MetaCyc:GKI-RXN|RHEA:27377|EC:2.7.1.- glycerate kinase|D-glycerate 2-kinase activity Catalysis of the reaction: D-glycerate + ATP = 2-phospho-D-glycerate + ADP. UBERON:0005095 kidney rudiment biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005095 kidney anlage . UBERON:0005094 beak biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005094 avian beak|rostrum|bill The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary ramaphotheca, mandibular ramaphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus[GO]. The beak, bill or rostrum is an external anatomical structure of birds which is used for eating and for grooming, manipulating objects, killing prey, probing for food, courtship and feeding young. . NCBITaxon:7711 Chordata organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_7711 chordates|chordates UBERON:0005082 tube lumen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005082 A hole in a tube[GO]. UBERON:0005081 ureter ureteric bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005081 The portion of the ureteric bud that contributes to the morphogenesis of the ureter. The ureter ureteric bud is the initial structure that forms the ureter[GO]. UBERON:0005080 metanephric ureteric bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005080 The portion of the ureteric bud tube that contributes to the morphogenesis of the metanephros[GO]. OBO:GOCHE_35623 substance with anticonvulsant role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_35623 UBERON:0005089 sweat gland placode biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005089 An sweat gland placode is a thickening of the ectoderm that will give rise to the sweat gland bud[GO]. UBERON:0005088 sebaceous gland placode biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005088 A sebaceous gland placode is a thickening of the ectoderm that will give rise to the sebaceous gland bud[GO]. UBERON:0005087 tooth placode biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005087 dental anlage|odontogenic placode|tooth germ|dental placode|tooth primordium|tooth anlage|dental primordium An tooth placode is a thickening of the ectoderm that will give rise to the tooth bud[GO]. UBERON:0005086 hair follicle placode biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005086 hair peg|hair gem|hair placode|vibrissa placode|hair germ A bud-like thickening in the epidermis consisting of elongated keratinocytes, which at the distal end are in touch with numerous aggregated specialized dermal fibroblasts, the dermal condensate. UBERON:0005085 ectodermal placode biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005085 epithelial placode An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm[GO] UBERON:0005083 nipple sheath biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005083 A circular ingrowth of the epidermis around the region of the mammary sprout[GO]. CHEBI:68501 dTDP-4-amino-4,6-dideoxy-alpha-D-glucose(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68501 UBERON:0005111 metanephric pyramid biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005111 Metanephric pyramids are the conical masses that constitute the renal medulla in a metanephros; they contain the loops of Henle and the medullary collecting ducts[GO]. CHEBI:68509 glutathione depleting agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68509 UBERON:0005110 metanephric nephron biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005110 A metanephric nephron is the functional unit of the metanephros[GO]. CHEBI:68506 (S)-3-ammonio-3-phenylpropanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68506 CHEBI:68508 diethyl maleate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68508 CHEBI:19569 2-deoxyribose phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19569 CHEBI:68507 UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68507 CHEBI:19568 2-deoxyribose bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19568 CHEBI:20568 5-deoxyribose phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20568 UBERON:0005119 metanephric glomerular mesangium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005119 The metanephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the metanephros, which helps to support the capillary loops in a renal glomerulus[GO]. UBERON:0005118 metanephric early distal convoluted tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005118 The metanephric early distal convoluted tubule contains metanephric DCT cells and is vasopressin-insensitive[GO]. CHEBI:19565 2-deoxyribose 5-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19565 CHEBI:20569 EC 2.5.1.19 (3-phosphoshikimate 1-carboxyvinyltransferase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20569 UBERON:0005117 metanephric distal convoluted tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005117 The metanephric distal convoluted tubule is a portion of the metanephric nephron tubule that connects the metanephric loop of Henle to the collecting duct[GO]. CHEBI:19564 2-deoxyribose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19564 UBERON:0005116 metanephric descending thin limb biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005116 It extends to the tip of the metanephric loop of Henle[GO]. UBERON:0005115 metanephric cortical collecting duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005115 The metanephric cortical collecting duct is the portion of the metanephric collecting duct that resides in the renal cortex[GO]. UBERON:0005114 metanephric ascending thin limb biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005114 The metanephric ascending thin limb is a segment of a nephron tubule in the metanephros lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent[GO]. UBERON:0005113 metanephric cortex mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005113 CHEBI:20570 5-hydroxycamphor biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_20570 NCBITaxon:7776 Gnathostomata organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_7776 Gnathostomata|jawed vertebrates CHEBI:68510 lysophosphatidylserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68510 UBERON:0005101 early distal convoluted tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005101 The early distal convoluted tubule contains DCT cells and is vasopressin-insensitive[GO]. UBERON:0005100 long descending thin limb biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005100 The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla[GO]. CHEBI:68516 dTDP-4-amino-4,6-dideoxy-alpha-D-galactose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68516 CHEBI:44526 (10E,12Z)-octadecadienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_44526 CHEBI:68518 dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68518 UBERON:0005109 metanephric smooth muscle tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005109 Any smooth muscle tissue that is part of a metanephros. UBERON:0005108 metanephric epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005108 An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure[GO]. UBERON:0005107 metanephric cap biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005107 condensed mesenchyme|cap mesenchyme The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip[GO]. Mesenchyme closely apposed to the tips of the buds is called cap mesenchyme; it will later go on to form nephrons etc[GUDMAP]. CHEBI:19555 2-deoxy-D-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19555 UBERON:0005106 metanephric tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005106 A metanephric tubule is an epithelial tube that is part of the metanephros[GO]. UBERON:0005105 posterior mesonephric tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005105 caudal mesonephric tubule . UBERON:0005104 anterior mesonephric tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005104 cranial mesonephric tubule . UBERON:0005103 mesonephric epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005103 An epithelium that is part of a mesonephros [Automatically generated definition]. UBERON:0005102 late distal convoluted tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005102 The late distal convoluted tubule contains DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive[GO]. CHEBI:19591 2-hexenal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_19591 NCBITaxon:7746 Petromyzontidae organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_7746 lampreys NCBITaxon:7745 Petromyzontiformes organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_7745 Petromyzoniformes|lampreys CHEBI:68523 dTDP-4-amino-4,6-dideoxy-alpha-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68523 CHEBI:68525 (S)-3-amino-3-phenylpropanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68525 CHEBI:44510 (S)-2-hydroxy-4-methylpentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_44510 CHEBI:68520 alkyl,acyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68520 CHEBI:68521 alkyl,acyl-sn-glycero-3-phosphoserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68521 CHEBI:68528 3-amino-3-phenylpropanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68528 CHEBI:68527 3-ammonio-3-phenylpropanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68527 CHEBI:68530 [beta-D-Galf-(1->5)-beta-D-Galf-(1->6)]14-beta-D-Galf-(1->5)-beta-D-Galf-(1->4)-alpha-L-Rhap-(1->3)-alpha-D-GlcpNAc-1-diphospho-trans,octacis-decaprenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68530 NCBITaxon:7762 Myxinidae organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_7762 hagfishes NCBITaxon:7761 Myxiniformes organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_7761 Myxinoidea|hagfishes CHEBI:19573 2-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19573 CHEBI:68546 phosphate group(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68546 UBERON:0005156 reproductive structure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005156 reproductive system element|reproductive system structure Any anatomical structure that is part of the reproductive system. UBERON:0005155 open tracheal system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005155 open tracheal system|tracheal system|invertebrate tracheal system An open tracheal system is a respiratory system, a branched network of epithelial tubes that supplies oxygen to target tissues via spiracles. An example of this is found in Drosophila melanogaster. UBERON:0005154 epithelial cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005154 A cord of epithelial cells without a lumen and usually several cells thick. UBERON:0005153 epithelial bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005153 A bud is a protrusion that forms from an epithelial sheet by localized folding. UBERON:0005151 metanephric proximal tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005151 The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology[GO]. CHEBI:68549 diphosphate group(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68549 UBERON:0005158 parenchyma of central nervous system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005158 central nervous system parenchyma|CNS parenchyma|parenchyma of central nervous system|parenchyma of CNS The functional tissue of the central nervous system consisting of neurons and glial cells. UBERON:0005157 epithelial fold biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005157 An epithelial sheet bent on a linear axis. GO:0043704 photoreceptor cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043704 The process in which a cell becomes capable of differentiating autonomously into a photoreceptor cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. UBERON:0005145 metanephric comma-shaped body biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005145 The metanephric comma-shaped body is the precursor structure to the metanephric S-shaped body that contributes to the morphogenesis of a nephron in the metanephros[GO]. GO:0043703 photoreceptor cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043703 The process in which a cell becomes capable of differentiating autonomously into a photoreceptor cell regardless of its environment; upon determination, the cell fate cannot be reversed. UBERON:0005144 metanephric glomerular capillary biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005144 This process pertains to the initial formation of a structure from unspecified parts[GO]. GO:0043706 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043706 GO:0043705 cyanophycin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043705 cyanophycin metabolism|multi-L-arginyl-poly(L-aspartic acid) metabolism The chemical reactions and pathways involving cyanophycin, a non-protein, non-ribosomally produced amino acid polymer composed of an aspartic acid backbone and arginine side groups. GO:0043700 pterinosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043700 A tissue-specific, membrane-bounded cytoplasmic organelle within which pteridine pigments are synthesized and stored. Pterinosomes are synthesized in xanthophores and erythrophore cells and are yellow, orange or red in appearance. UBERON:0005141 metanephric short descending thin limb biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005141 The metanephric short descending thin limb is the descending thin limb of a short nephron in the metanephros that has a squamous epithelial morphology[GO]. UBERON:0005140 metanephric short nephron biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005140 Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb[GO]. CHEBI:19515 2-cis,6-trans-farnesyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19515 GO:0043702 carotenoid vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043702 A tissue-specific cytoplasmic vesicle surrounded by a membrane half-leaflet within which carotenoid pigments are stored. Carotenoid vesicles are synthesized in xanthophores and erythrophore cells and are yellow, orange or red in appearance. GO:0043701 cyanosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043701 A tissue-specific, membrane-bounded cytoplasmic organelle within which an unknown blue pigment is localized. Cyanosomes are synthesized in cyanophores and are blue in appearance. CHEBI:19511 2-cis,6-cis-farnesyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19511 GO:0043708 cell adhesion involved in biofilm formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043708 cell adhesion during biofilm formation The attachment of a cell to a solid substrate, via cell adhesion molecules, contributing to the formation of a biofilm. UBERON:0005149 metanephric connecting tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005149 The metanephric connecting tubule is a tubular segment of the metanephric nephron; it connects the distal convoluted tubule to the collecting duct in the metanephros[GO]. UBERON:0005148 metanephric S-shaped body biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005148 The metanephric S-shaped body is the successor of the metanephric comma-shaped body that contributes to the morphogenesis of a nephron in the metanephros[GO]. GO:0043707 cell adhesion involved in single-species biofilm formation in or on host organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043707 cell adhesion during single-species biofilm formation in or on host organism The attachment of a cell to either a host cell or a microbial cell of the same species, or to an underlying host substrate, such as the extracellular matrix, via cell adhesion molecules, occurring during the formation of a biofilm in or on a host species. UBERON:0005147 metanephric renal vesicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005147 metanephric vesicle The renal vesicle is the primordial structure of the metanephric nephron epithelium, and is formed by the condensation of mesenchymal cells[GO]. GO:0043709 cell adhesion involved in single-species biofilm formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043709 cell adhesion during single-species biofilm formation The attachment of a cell to a solid substrate, via cell adhesion molecules, during the formation of a biofilm composed of microorganisms of the same species. UBERON:0005146 metanephric nephron tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005146 A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros[GO]. CHEBI:68560 UDP-N-acetyl-6-(alpha-D-galactose-1-phosphonato)-alpha-D-glucosamine(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68560 CHEBI:68563 P2Y12 receptor antagonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68563 GO:0043715 2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043715 MetaCyc:R82-RXN|RHEA:18769|EC:5.3.2.5 MasA|DK-MTP-1-P enolase activity|mtnW|E-1 Catalysis of the reaction: 2,3-diketo-5-methylthiopentyl-1-phosphate = H+ + 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate. 2,3-diketo-5-methylthiopentyl-1-phosphate is also known as DK-MTP-1-P, and 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate as HK-MTPenyl-1-P. UBERON:0005134 metanephric nephron epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005134 The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros[GO]. GO:0043714 (R)-citramalate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043714 EC:2.3.1.182|MetaCyc:RXN-7743|RHEA:19045 citramalate synthase Catalysis of the reaction: pyruvate + acetyl-CoA + H2O = (R)-citramalate + CoA. UBERON:0005133 metanephric glomerulus vasculature biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005133 The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus[GO]. GO:0043717 2-hydroxyglutaryl-CoA dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043717 RHEA:42448|MetaCyc:RXN-1083 (R)-2-hydroxyglutaryl-CoA dehydratase activity Catalysis of the reaction: (R)-2-hydroxyglutaryl-CoA = H2O + glutaconyl-CoA. UBERON:0005132 metanephric long nephron biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005132 Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla in the metanephros[GO]. GO:0043716 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043716 MetaCyc:R83-RXN|RHEA:14481|KEGG_REACTION:R07394 2-hydroxy-3-keto-5-methylthio-phosphopentene phosphatase activity|HK-MTPenyl-1-P phosphatase activity Catalysis of the reaction: 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate. 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate is also known as HK-MTPenyl-P, and 1,2-dihydroxy-3-keto-5-methylthiopentene as DHK-MTPene. UBERON:0005130 metanephric loop of Henle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005130 The metanephric loop of Henle is a metanephric nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule in the metanephros[GO]. GO:0043711 pilus organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043711 pilus organisation|pilus organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pilus, a short filamentous structure on a bacterial cell, flagella-like in structure and generally present in many copies. GO:0043710 cell adhesion involved in multi-species biofilm formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043710 cell adhesion during multi-species biofilm formation The attachment of a cell to a solid substrate, via cell adhesion molecules, contributing to the formation of a biofilm composed of microorganisms of different species. GO:0043713 (R)-2-hydroxyisocaproate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043713 Catalysis of the reaction: 2-oxoisocaproate + NADH + H+ = (R)-2-hydroxyisocaproate + NAD+. GO:0043712 2-hydroxyisocaproate CoA-transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043712 (R)-2-hydroxyisocaproate CoA transferase activity|(R)-2-hydroxyisocaproate CoA-transferase activity Catalysis of the reaction: (R)-2-hydroxyisocaproate + isocaproyl-CoA = (R)-2-hydroxyisocaproyl-CoA + isocaproate. CHEBI:20502 5,10-methylenetetrahydrofolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20502 CHEBI:19543 2-dehydro-L-idonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19543 UBERON:0005139 metanephric long descending thin limb biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005139 GO:0043719 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043719 MetaCyc:OCTAPRENYL-METHYL-METHOXY-BENZOQ-OH-RXN|EC:1.14.13.- Catalysis of the reaction: 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol + O2 + H+ = 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol + H2O. CHEBI:20506 5,6,7,8-tetrahydrofolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20506 GO:0043718 2-hydroxymethylglutarate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043718 Wikipedia:2-hydroxymethylglutarate_dehydrogenase|MetaCyc:1.1.1.291-RXN|EC:1.1.1.291|RHEA:15505|KEGG_REACTION:R07985 (S)-2-hydroxymethylglutarate:NAD+ oxidoreductase activity|HgD Catalysis of the reaction: 2-(hydroxymethyl)glutarate + NAD(+) = 2-formylglutarate + H(+) + NADH. UBERON:0005137 metanephric capsule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005137 The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage[GO]. UBERON:0005136 metanephric glomerular endothelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005136 The metanephric glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus of the metanephros[GO]. UBERON:0005135 metanephric glomerular epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005135 A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros[GO]. GO:0043720 3-keto-5-aminohexanoate cleavage activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043720 MetaCyc:R125-RXN|RHEA:31555 3-keto-5-aminohexanoate cleavage enzyme Catalysis of the reaction: 3-keto-5-aminohexanoate + acetyl-CoA = L-3-aminobutyryl-CoA + acetoacetate. CHEBI:68576 dTDP-6-deoxy-beta-L-talose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68576 GO:0043726 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043726 RHEA:25197|MetaCyc:RIBOPHOSPHAT-RXN pyrimidine phosphatase activity Catalysis of the reaction: 5-amino-6-(5-phosphoribitylamino)-2,4(1H,3H)-pyrimidinedione + H2O = 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione + orthophosphate. UBERON:0005123 metanephric prebend segment biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005123 The metanephric prebend segment is a part of the metanephric descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability[GO]. GO:0043725 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043725 UBERON:0005122 metanephric macula densa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005122 The metanephric macula densa is an area of specialized cells in the distal tubule of the metanephros that makes contact with the vascular pole of the glomerulus[GO]. UBERON:0005121 metanephric long descending thin limb bend biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005121 The metanephric long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment in the metanephros[GO]. GO:0043728 2-keto-4-methylthiobutyrate aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043728 EC:4.1.1.- Catalysis of the reaction: 2-keto-4-methylthiobutyrate + L-glutamine = 2-oxoglutaramate + L-methionine. GO:0043727 5-amino-4-imidazole carboxylate lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043727 EC:4.1.1.21 Catalysis of the reaction: 5-aminoimidazole + CO2 = 5-amino-4-imidazole carboxylate. UBERON:0005120 metanephric late distal convoluted tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005120 The metanephric late distal convoluted tubule contains metanephric DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive[GO]. GO:0043722 4-hydroxyphenylacetate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043722 EC:4.1.1.83|KEGG_REACTION:R07312|MetaCyc:4.1.1.83-RXN|RHEA:22732 4-hydroxyphenylacetate carboxy-lyase activity|4-(hydroxyphenyl)acetate carboxy-lyase (4-methylphenol-forming)|p-Hpd activity|p-hydroxyphenylacetate decarboxylase activity|4-Hpd activity Catalysis of the reaction: (4-hydroxyphenyl)acetate + H(+) = 4-cresol + CO(2). GO:0043721 4-hydroxybutanoyl-CoA dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043721 RHEA:26530|EC:4.2.1.120|MetaCyc:RXN-8890|KEGG_REACTION:R05337 gamma-hydroxybutanoyl-CoA dehydratase activity|gamma-hydroxybutyryl-CoA dehydratase activity|4-hydroxybutanoyl-CoA hydro-lyase|4-hydroxybutyryl-CoA dehydratase activity Catalysis of the reaction: 4-hydroxybutanoyl-CoA = vinylacetyl-CoA + H2O. GO:0043724 2-keto-3-deoxygalactonate aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043724 KDGal aldolase activity Catalysis of the reaction: 2-keto-3-deoxygalactonate = D-glyceraldehyde + pyruvate. GO:0043723 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043723 MetaCyc:RXN-10058 2,5-diamino-6-(5-phosphoribitylamino)pyrimidin-4(3H)-one deaminase activity|DRAP deaminase activity Catalysis of the reaction: 2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one + H2O = 5-amino-6-(5-phospho-D-ribosylamino)uracil + ammonia. UBERON:0005129 metanephric distal tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005129 The metanephric distal tubule is a metanephric nephron tubule that begins at the metanephric macula densa and extends to the metanephric connecting tubule[GO]. CHEBI:20515 5,6-dioxidoindole-2-carboxylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20515 UBERON:0005127 metanephric thick ascending limb biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005127 At the macula densa, the thick ascending limb connects to the distal convoluted tubule[GO]. GO:0043729 2-amino-5-formylamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one formate-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043729 Catalysis of the reaction: 2-amino-5-formylamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one + H2O = 2,5-diamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one + formate. UBERON:0005126 metanephric S1 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005126 The S1 portion is the initial portion of the metanephric proximal convoluted tubule and is responsible for avid reabsorption of water and solutes[GO]. UBERON:0005125 metanephric proximal straight tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005125 The metanephric proximal straight tubule is the part of the metanephric descending limb that extends from the metanephric proximal convoluted tubule to the metanephric descending thin tubule[GO]. UBERON:0005124 metanephric proximal convoluted tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005124 The metanephric proximal convoluted tubule is the most proximal portion of the metanephric proximal tubule and extends from the metanephric glomerular capsule to the metanephric proximal straight tubule[GO]. GO:0004129 cytochrome-c oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004129 MetaCyc:CYTOCHROME-C-OXIDASE-RXN|RHEA:11436|EC:7.1.1.9|Reactome:R-HSA-163214 aa3-type cytochrome c oxidase|cytochrome a3 activity|cytochrome c oxidase activity|cbb3-type cytochrome c oxidase|caa3-type cytochrome c oxidase|complex IV (mitochondrial electron transport) activity|indophenolase|indophenol oxidase|cytochrome aa3 activity|Warburg's respiratory enzyme activity|cytochrome oxidase activity|ba3-type cytochrome c oxidase Catalysis of the reaction: 4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O. GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004128 MetaCyc:CYTOCHROME-B5-REDUCTASE-RXN|Reactome:R-HSA-6806831|EC:1.6.2.2|RHEA:46680|Reactome:R-HSA-198824 NADH:ferricytochrome-b5 oxidoreductase activity|cytochrome b5 reductase activity|NADH-cytochrome b5 reductase activity|reduced nicotinamide adeninedinucleotide-cytochrome b5 reductase activity|NADH-cytochrome-b5 reductase activity|NADH-ferricytochrome b5 oxidoreductase activity|dihydronicotinamide adenine dinucleotide-cytochrome b5 reductase activity|NADH 5alpha-reductase activity Catalysis of the reaction: NAD(P)H + H+ + 2 ferricytochrome b(5) = NAD(P)+ + 2 ferrocytochrome b(5). GO:0004125 L-seryl-tRNASec selenium transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004125 MetaCyc:2.9.1.1-RXN|EC:2.9.1.1|RHEA:22728 L-selenocysteinyl-tRNA(Sel) synthase activity|L-seryl-tRNA(Ser) selenium transferase activity|selenophosphate:L-seryl-tRNASec selenium transferase activity|L-selenocysteinyl-tRNASec synthase activity|cysteinyl-tRNA(Sec)-selenium transferase activity|selenocysteinyl-tRNA(Ser) synthase activity|cysteinyl-tRNASel-selenium transferase activity|cysteinyl-tRNA(Ser) selenium transferase activity|cysteinyl-tRNA(Sel)-selenium transferase activity|cysteinyl-tRNASec-selenium transferase activity|L-selenocysteinyl-tRNA(Sec) synthase activity|selenocysteine synthase activity|L-selenocysteinyl-tRNASel synthase activity Catalysis of the reaction: L-seryl-tRNA(Sec) + selenophosphate = L-selenocysteinyl-tRNA(Sec) + H2O + phosphate. GO:0004124 cysteine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004124 MetaCyc:ACSERLY-RXN|RHEA:14829|EC:2.5.1.47 O-acetylserine (thiol)-lyase activity|3-O-acetyl-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase activity|O3-acetyl-L-serine acetate-lyase (adding hydrogen-sulfide)|OAS sulfhydrylase activity|O-acetylserine sulfhydrylase activity|acetylserine sulfhydrylase activity|O-acetylserine (thiol)-lyase A activity|O-acetyl-L-serine sulfhydrylase activity|O3-acetyl-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase activity|cysteine synthetase activity|O(3)-acetyl-L-serine acetate-lyase (adding hydrogen-sulfide) activity|O-acetyl-L-serine sulfohydrolase activity Catalysis of the reaction: O3-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate. GO:0004127 cytidylate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004127 MetaCyc:CMPKI-RXN|EC:2.7.4.14 cytidine monophosphate kinase activity|CTP:CMP phosphotransferase activity|ATP:CMP phosphotransferase activity|pyrimidine nucleoside monophosphate kinase activity|deoxycytidine monophosphokinase activity|UMP-CMP kinase activity|CMP kinase activity|deoxycytidylate kinase activity|dCMP kinase activity|ATP:UMP-CMP phosphotransferase activity Catalysis of the reaction: ATP + (d)CMP = ADP + (d)CDP. GO:0004126 cytidine deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004126 EC:3.5.4.5|RHEA:16069|MetaCyc:CYTIDEAM2-RXN|Reactome:R-HSA-83677|Reactome:R-HSA-73608 cytidine aminohydrolase activity|cytosine nucleoside deaminase activity Catalysis of the reaction: cytidine + H2O = uridine + NH3. GO:0004121 cystathionine beta-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004121 RHEA:13965|MetaCyc:CYSTATHIONINE-BETA-LYASE-RXN|EC:4.4.1.8 beta-cystathionase activity|cystine lyase activity|L-cystathionine L-homocysteine-lyase (deaminating; pyruvate-forming)|L-cystathionine L-homocysteine-lyase (deaminating)|cystathionine L-homocysteine-lyase (deaminating)|beta C-S lyase activity Catalysis of the reaction: cystathionine + H2O = L-homocysteine + NH3 + pyruvate. GO:0004120 photoreceptor cyclic-nucleotide phosphodiesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004120 Catalysis of the reaction: nucleoside cyclic phosphate + H2O = nucleoside phosphate. This reaction is the hydrolysis of bonds in a cyclic nucleotide. GO:0004123 cystathionine gamma-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004123 KEGG_REACTION:R01001|Reactome:R-HSA-1614583|RHEA:14005|EC:4.4.1.1|MetaCyc:CYSTAGLY-RXN homoserine dehydratase activity|gamma-cystathionase activity|homoserine deaminase activity|L-cystathionine cysteine-lyase (deaminating)|L-cystathionine cysteine-lyase (deaminating; 2-oxobutanoate-forming)|homoserine deaminase-cystathionase activity Catalysis of the reaction: L-cystathionine + H2O = 2-oxobutanoate + L-cysteine + NH4+. GO:0004122 cystathionine beta-synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004122 EC:4.2.1.22|RHEA:10112|MetaCyc:CYSTATHIONINE-BETA-SYNTHASE-RXN|Reactome:R-HSA-1614524 beta-thionase activity|L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|serine sulfhydrylase activity|methylcysteine synthase activity|L-serine hydro-lyase (adding homocysteine)|serine sulfhydrase activity Catalysis of the reaction: L-serine + L-homocysteine = cystathionine + H2O. GO:0018769 2-hydroxy-6-oxoocta-2,4-dienoate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018769 UM-BBD_reactionID:r0311 Catalysis of the reaction: 2-hydroxy-6-oxoocta-2,4-dienoate + H2O = H+ + propanoate + cis-2-hydroxypenta-2,4-dienoate. CHEBI:138745 2-[(9S,11R)-epidioxy-(15S)-hydroxy-(5Z,13E)-prostadienoyl]-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138745 CHEBI:138744 2-[(9S,11R)-epidioxy-(15S)-hydroperoxy-(5Z,13E)-prostadienoyl]-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138744 GO:0018766 dihydrophloroglucinol hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018766 UM-BBD_reactionID:r0008|MetaCyc:R6-RXN|KEGG_REACTION:R07831 Catalysis of the reaction: dihydrophloroglucinol + OH- = 3-hydroxy-5-oxohexanoate. GO:0018765 2-hydroxy-6-oxohepta-2,4-dienoate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018765 MetaCyc:2-OH-6-OXOHEPTA-2-4-DIENOATE-HYDR-RXN|UM-BBD_reactionID:r0263|RHEA:59220 Catalysis of the reaction: cis,cis-2-hydroxy-6-oxohept-2,4-dienoate + OH- = cis-2-hydroxypenta-2,4-dienoate + acetate. GO:0018768 2-hydroxy-6-oxo-6-(2'-aminophenyl)hexa-2,4-dienoate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018768 UM-BBD_reactionID:r0458|EC:3.7.1.13 Catalysis of the reaction: 2-hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoate + H2O = 2-aminobenzoate + cis-2-hydroxypenta-2,4-dienoate. GO:0018767 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018767 UM-BBD_reactionID:r0399 Catalysis of the reaction: 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate + H2O = cis-2-hydroxypenta-2,4-dienoate + isobutyrate. GO:0018762 aliphatic nitrilase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018762 MetaCyc:3.5.5.7-RXN|UM-BBD_reactionID:r0622|EC:3.5.5.7|RHEA:46188 aliphatic nitrile aminohydrolase activity Catalysis of the reaction: R-CN + H2O = R-COOH + NH3. GO:0018761 bromoxynil nitrilase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018761 UM-BBD_enzymeID:e0357|MetaCyc:3.5.5.6-RXN|KEGG_REACTION:R04349|EC:3.5.5.6|RHEA:22100 3,5-dibromo-4-hydroxybenzonitrile aminohydrolase activity|bromoxynil-specific nitrilase activity Catalysis of the reaction: 3,5-dibromo-4-hydroxybenzonitrile + 2 H(2)O = 3,5-dibromo-4-hydroxybenzoate + NH(4)(+). Involved in the bacterial degradation of the herbicide bromoxynil. GO:0018764 N-isopropylammelide isopropylaminohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018764 RHEA:23608|UM-BBD_enzymeID:e0086|MetaCyc:R123-RXN|EC:3.5.4.42 AtzC Catalysis of the reaction: N-isopropylammelide + H2O = cyanuric acid + isopropylamine. GO:0018763 hydroxydechloroatrazine ethylaminohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018763 UM-BBD_enzymeID:e0085|MetaCyc:R122-RXN|EC:3.5.4.43|RHEA:23092 AtzB|hydroxyatrazine ethylaminohydrolase activity|4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine ethylaminohydrolase activity|hydroxyatrazine hydrolase activity Catalysis of the reaction: 4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine + H2O = N-isopropylammelide + ethylamine. GO:0018760 thiocyanate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018760 MetaCyc:RXN-1761|UM-BBD_reactionID:r0598|EC:3.5.5.8|RHEA:21464|KEGG_REACTION:R05780 thiocyanate aminohydrolase activity Catalysis of the reaction: H(2)O + 2 H(+) + thiocyanate = carbonyl sulfide + NH(4)(+). GO:0004139 deoxyribose-phosphate aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004139 MetaCyc:DEOXYRIBOSE-P-ALD-RXN|RHEA:12821|Reactome:R-HSA-6787321|KEGG_REACTION:R01066|EC:4.1.2.4 phosphodeoxyriboaldolase activity|2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase activity|2-deoxyribose-5-phosphate aldolase activity|deoxyribose-5-phosphate aldolase activity|2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase (D-glyceraldehyde-3-phosphate-forming)|deoxyriboaldolase activity Catalysis of the reaction: 2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde. GO:0004136 deoxyadenosine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004136 MetaCyc:DEOXYADENOSINE-KINASE-RXN|EC:2.7.1.76|KEGG_REACTION:R02089|RHEA:23452 purine-deoxyribonucleoside kinase activity|deoxyadenosine kinase (phosphorylating)|ATP:deoxyadenosine 5'-phosphotransferase activity Catalysis of the reaction: 2'-deoxyadenosine + ATP = ADP + dAMP + 2 H(+). GO:0004135 amylo-alpha-1,6-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004135 EC:3.2.1.33|Reactome:R-HSA-71593|MetaCyc:3.2.1.33-RXN dextrin 6-alpha-D-glucosidase activity|amylo-1,6-glucosidase activity|glycogen phosphorylase-limit dextrin alpha-1,6-glucohydrolase activity|dextrin-1,6-glucosidase activity|amylopectin 1,6-glucosidase activity Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin. Limit dextrin is the highly branched core that remains after exhaustive treatment of glycogen with glycogen phosphorylase. It is formed because these enzymes cannot hydrolyze the (1->6) glycosidic linkages present. GO:0004138 deoxyguanosine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004138 KEGG_REACTION:R01967|EC:2.7.1.113|MetaCyc:DEOXYGUANOSINE-KINASE-RXN|RHEA:19201 ATP:deoxyguanosine 5'-phosphotransferase activity|2'-deoxyguanosine kinase activity|NTP-deoxyguanosine 5'-phosphotransferase activity|(dihydroxypropoxymethyl)guanine kinase activity|deoxyguanosine kinase (phosphorylating) Catalysis of the reaction: 2'-deoxyguanosine + ATP = ADP + dGMP + 2 H(+). GO:0004137 deoxycytidine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004137 EC:2.7.1.74|MetaCyc:DEOXYCYTIDINE-KINASE-RXN|RHEA:20061 deoxycytidine kinase (phosphorylating)|arabinofuranosylcytosine kinase activity|Ara-C kinase activity|2'-deoxycytidine kinase activity|deoxycytidine-cytidine kinase activity|NTP:deoxycytidine 5'-phosphotransferase activity Catalysis of the reaction: NTP + deoxycytidine = NDP + CMP. GO:0004132 dCMP deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004132 Reactome:R-HSA-73596|RHEA:22924|EC:3.5.4.12|MetaCyc:DCMP-DEAMINASE-RXN deoxycytidine monophosphate deaminase activity|deoxycytidylate deaminase activity|dCMP aminohydrolase activity|deoxycytidine-5'-phosphate deaminase activity|deoxy-CMP-deaminase activity|deoxycytidine-5'-monophosphate aminohydrolase activity|deoxycytidylate aminohydrolase activity Catalysis of the reaction: dCMP + H2O = dUMP + NH3. GO:0004131 cytosine deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004131 RHEA:20605|MetaCyc:CYTDEAM-RXN|EC:3.5.4.1 cytosine aminohydrolase activity|isocytosine deaminase activity Catalysis of the reaction: cytosine + H2O = uracil + NH3. GO:0004134 4-alpha-glucanotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004134 MetaCyc:AMYLOMALT-RXN|EC:2.4.1.25|MetaCyc:RXN-9023|Reactome:R-HSA-71552|MetaCyc:RXN-1828 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase activity|dextrin transglycosylase activity|disproportionating enzyme activity|dextrin glycosyltransferase activity|oligo-1,4-1,4-glucantransferase activity|amylomaltase activity|debranching enzyme maltodextrin glycosyltransferase activity|D-enzyme activity Catalysis of the transfer of a segment of a (1->4)-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or (1->4)-alpha-D-glucan. GO:0004133 glycogen debranching enzyme activity biolink:MolecularActivity go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0004133 Catalysis of the cleavage of branch points in branched glycogen polymers. GO:0004130 cytochrome-c peroxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004130 MetaCyc:CYTOCHROME-C-PEROXIDASE-RXN|EC:1.11.1.5|RHEA:16581 cytochrome c-551 peroxidase activity|apocytochrome c peroxidase activity|cytochrome c peroxidase activity|cytochrome peroxidase activity|ferrocytochrome-c:hydrogen-peroxide oxidoreductase activity|cytochrome c-H2O oxidoreductase activity|mesocytochrome c peroxidase azide|mesocytochrome c peroxidase cyanate|mesocytochrome c peroxidase cyanide Catalysis of the reaction: 2 ferrocytochrome c + hydrogen peroxide = 2 ferricytochrome c + 2 H2O. GO:0018777 1,3,4,6-tetrachloro-1,4-cyclohexadiene halidohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018777 Catalysis of the reaction: alkyl halide + H2O = alcohol + HCl. Substrates are 1,3(R),4,6(R)-tetrachloro-1,4-cyclohexadiene (forms 2,4,5-trichloro-2,5-cyclohexadiene-1-ol) and 2,4,5-trichloro-2,5-cyclohexadiene-1-ol (forms 2,5-dichloro-2,5-cyclohexadiene-1,4-diol). GO:0018776 trans-chloroacrylic acid dehalogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018776 UM-BBD_reactionID:r0689 Catalysis of the reaction: trans-3-chloroacrylic acid + H2O = H+ + malonate semialdehyde. GO:0018779 obsolete 2-chloro-4,6-dihydroxy-1,3,5-triazine hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018779 2-chloro-4,6-dihydroxy-1,3,5-triazine hydrolase activity OBSOLETE. (Was not defined before being made obsolete). GO:0018778 DL-2 haloacid dehalogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018778 MetaCyc:RXN-9150|EC:3.8.1.10|UM-BBD_reactionID:r0382 Catalysis of the reaction: trichloroacetate + 2 H2O = 3 H+ + 3 Cl- + oxalate. GO:0018773 acetylpyruvate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018773 EC:3.7.1.6|UM-BBD_reactionID:r0095|MetaCyc:ACETYLPYRUVATE-HYDROLASE-RXN|RHEA:16097|KEGG_REACTION:R00324 2,4-dioxopentanoate acetylhydrolase activity Catalysis of the reaction: acetylpyruvate + H(2)O = acetate + H(+) + pyruvate. GO:0018772 trioxoheptanoate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018772 UM-BBD_reactionID:r0094|MetaCyc:R306-RXN Catalysis of the reaction: 2,4,6-trioxoheptanoate + H2O = acetylpyruvate + acetate. GO:0018775 2-hydroxymuconate-semialdehyde hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018775 EC:3.7.1.9|UM-BBD_enzymeID:e0139|MetaCyc:3.7.1.9-RXN|RHEA:14549 2-hydroxymuconic semialdehyde hydrolase activity|2-hydroxymuconate-semialdehyde formylhydrolase activity|HOD hydrolase activity|HMSH Catalysis of the reaction: 2-hydroxymuconate semialdehyde + H2O = formate + 2-oxopent-4-enoate. GO:0018774 2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018774 EC:3.7.1.8|RHEA:17161|UM-BBD_enzymeID:e0033|MetaCyc:3.7.1.8-RXN 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase activity|HOHPDA hydrolase activity|2,6-dioxo-6-phenylhexa-3-enoate benzoylhydrolase activity Catalysis of the reaction: 2,6-dioxo-6-phenylhexa-3-enoate + H2O = benzoate + 2-oxopent-4-enoate. GO:0018771 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018771 MetaCyc:MHPCHYDROL-RXN|UM-BBD_reactionID:r0438|RHEA:24789|EC:3.7.1.14 2-hydroxy-6-ketonona-2,4-dienedoic acid hydrolase activity|(2E,4Z)-2-hydroxy-6-oxona-2,4-dienedioate succinylhydrolase activity Catalysis of the reaction: (2E,4Z)-2-hydroxy-6-oxonona-2,4-dienedioate + H2O = (2E)-2-hydroxypenta-2,4-dienoate + H+ + succinate. GO:0018770 6-oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7-trienoate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018770 UM-BBD_reactionID:r0444 Catalysis of the reaction: 6-oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8-trichloroocta-2Z,4Z,7-trienoate + H2O = 2-(4'-chlorophenyl)-3,3-dichloropropenoate + cis-2-Hydroxy-3-chloropenta-2,4-dienone + H+. GO:0004107 chorismate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004107 KEGG_REACTION:R01714|EC:4.2.3.5|RHEA:21020|MetaCyc:CHORISMATE-SYNTHASE-RXN 5-O-(1-carboxyvinyl)-3-phosphoshikimate phosphate-lyase (chorismate-forming)|5-O-(1-carboxyvinyl)-3-phosphoshikimate phosphate-lyase activity|5-enolpyruvylshikimate-3-phosphate phospholyase activity Catalysis of the reaction: 5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. GO:0004106 chorismate mutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004106 KEGG_REACTION:R01715|RHEA:13897|MetaCyc:CHORISMATEMUT-RXN|EC:5.4.99.5 hydroxyphenylpyruvate synthase activity|chorismate pyruvatemutase activity Catalysis of the reaction: chorismate = prephenate. GO:0004109 coproporphyrinogen oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004109 Reactome:R-HSA-189421|MetaCyc:RXN0-1461|KEGG_REACTION:R03220|RHEA:18257|EC:1.3.3.3 coproporphyrinogen:oxygen oxidoreductase (decarboxylating)|coprogen oxidase activity|coproporphyrinogenase activity|coproporphyrinogen-III oxidase activity Catalysis of the reaction: coproporphyrinogen III + 2 H(+) + O(2) = 2 CO(2) + 2 H(2)O + protoporphyrinogen IX. GO:0004108 citrate (Si)-synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004108 MetaCyc:CITSYN-RXN|EC:2.3.3.1|Reactome:R-HSA-70975 citrate oxaloacetate-lyase ((pro-3S)-CH(2)COO(-)->acetyl-CoA) activity|citrate oxaloacetate-lyase [(pro-3S)-CH2COOrightacetyl-CoA]|citrate oxaloacetate-lyase ((pro-3S)-CH2COO-rightacetyl-CoA)|(R)-citric synthase activity|condensing enzyme activity|citrate oxaloacetate-lyase, CoA-acetylating activity|citrogenase activity|citrate synthase activity|oxaloacetate transacetase activity|citrate condensing enzyme activity|citric-condensing enzyme activity|citric synthase activity|citrate synthetase activity|oxalacetic transacetase activity|acetyl-CoA:oxaloacetate C-acetyltransferase [thioester-hydrolysing, (pro-S)-carboxymethyl forming] Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA, where the acetyl group is added to the si-face of oxaloacetate; acetyl-CoA thus provides the two carbon atoms of the pro-S carboxymethyl group. GO:0004103 choline kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004103 RHEA:12837|EC:2.7.1.32|KEGG_REACTION:R01021|Reactome:R-HSA-1483004|MetaCyc:CHOLINE-KINASE-RXN choline phosphokinase activity|choline kinase (phosphorylating)|choline-ethanolamine kinase activity|ATP:choline phosphotransferase activity Catalysis of the reaction: ATP + choline = ADP + choline phosphate + 2 H(+). GO:0004102 choline O-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004102 KEGG_REACTION:R01023|Reactome:R-HSA-264622|RHEA:18821|EC:2.3.1.6|MetaCyc:CHOLINE-O-ACETYLTRANSFERASE-RXN choline acetyltransferase activity|CHOACTase activity|choline acetylase activity|acetyl-CoA:choline O-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + choline = acetylcholine + CoA. GO:0004105 choline-phosphate cytidylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004105 EC:2.7.7.15|RHEA:18997|Reactome:R-HSA-1483081|MetaCyc:2.7.7.15-RXN phosphorylcholine transferase activity|CDP-choline pyrophosphorylase activity|cytidine diphosphocholine pyrophosphorylase activity|phosphocholine cytidylyltransferase activity|CDP-choline synthetase activity|CTP:phosphocholine cytidylyltransferase activity|choline phosphate cytidylyltransferase activity|phosphorylcholine:CTP cytidylyltransferase activity|CTP:phosphorylcholine cytidylyltransferase activity|phosphorylcholine cytidylyltransferase activity|CTP:choline-phosphate cytidylyltransferase activity|CTP-phosphocholine cytidylyltransferase activity Catalysis of the reaction: CTP + choline phosphate = diphosphate + CDP-choline. GO:0004104 cholinesterase activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0004104 MetaCyc:CHOLINESTERASE-RXN|RHEA:21964|EC:3.1.1.8 choline esterase activity|pseudocholinesterase activity|BtChoEase activity|acylcholine acylhydrolase activity|butyrylcholine esterase activity|butyrylcholinesterase activity|non-specific cholinesterase activity|choline esterase II (unspecific) activity|benzoylcholinesterase activity|anticholineesterase activity|propionylcholinesterase activity Catalysis of the reaction: an acylcholine + H2O = choline + a carboxylic acid anion. GO:0004101 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004101 GO:0004100 chitin synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004100 RHEA:16637|MetaCyc:CHITIN-SYNTHASE-RXN|EC:2.4.1.16 chitin-UDP acetyl-glucosaminyl transferase activity|UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase activity|trans-N-acetylglucosaminosylase activity|chitin-uridine diphosphate acetylglucosaminyltransferase activity|chitin synthetase activity|chitin-UDP N-acetylglucosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n) = UDP + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n+1). GO:0018748 iprodione amidohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018748 UM-BBD_reactionID:r0706 Catalysis of the reaction: iprodione + OH- = 3,5-dichlorophenylcarboximide + N-isopropylcarbamate. CHEBI:138724 all-trans-retinyl heptanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138724 GO:0018747 phenanthrene-1,2-epoxide hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018747 UM-BBD_reactionID:r0536 Catalysis of the reaction: phenanthrene-1,2-oxide + H2O = trans-1,2-dihydrodiolphenanthrene. CHEBI:138723 1-oleoyl-2-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138723 CHEBI:138722 13-cis-retinyl hexadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138722 GO:0018749 (3,5-dichlorophenylurea)acetate amidohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018749 UM-BBD_reactionID:r0708 Catalysis of the reaction: (3,5-dichlorophenylurea)acetate + OH- = 3,5-dichloroaniline + N-carboxyglycine. CHEBI:138721 tetradecyl tetradecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138721 GO:0018744 limonene-1,2-epoxide hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018744 UM-BBD_reactionID:r0734|RHEA:10700|MetaCyc:3.3.2.8-RXN|EC:3.3.2.8 limonene oxide hydrolase activity Catalysis of the reaction: limonene-1,2-epoxide + H2O = limonene-1,2-diol. Other substrates include alicyclic and 1-methyl-substituted epoxides, such as 1-methylcyclohexene oxide, indene oxide and cyclohexene oxide. GO:0018743 phenanthrene-9,10-epoxide hydrolase (9R,10R-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018743 EC:3.3.2.-|UM-BBD_reactionID:r0560 Catalysis of the reaction: phenanthrene-9,10-oxide + H2O = trans-9R,10R-dihydrodiolphenanthrene. GO:0018746 phenanthrene-3,4-epoxide hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018746 UM-BBD_reactionID:r0535 Catalysis of the reaction: phenanthrene-3,4-oxide + H2O = trans-3,4-dihydrodiolphenanthrene. CHEBI:138726 3'-unsubstituted flavone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138726 GO:0018745 epoxide hydrolase A activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018745 EC:3.3.2.-|UM-BBD_enzymeID:e0049 Catalysis of the hydrolysis of the ether in chloro-, bromo- or hydroxyepoxypropane to produce a chloro- or bromopropane diol or glycerol. GO:0018740 2'-hydroxybiphenyl-2-sulfinate desulfinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018740 MetaCyc:RXN-624|EC:3.13.1.3|UM-BBD_enzymeID:e0216|RHEA:12945|KEGG_REACTION:R07311 DszB|2-(2-hydroxyphenyl) benzenesulfinate:H2O hydrolase activity|gene dszB-encoded hydrolase activity|HBPSi desulfinase activity|2-(2-hydroxyphenyl)benzenesulfinate desulfinase activity|2-(2'-hydroxyphenyl)benzenesulfinate desulfinase activity|dibenzothiophene desulfurization enzyme B|2'-hydroxybiphenyl-2-sulfinate sulfinolyase activity|2'-hydroxybiphenyl-2-sulfinate sulfohydrolase activity|2-(2-hydroxyphenyl)benzenesulfinate hydrolase activity|HPBS desulfinase activity|2-(2-hydroxyphenyl) benzenesulfinate sulfohydrolase activity|2-(2-hydroxyphenyl)benzenesulphinate hydrolase activity Catalysis of the reaction: 2'-hydroxybiphenyl-2-sulfinate + H(2)O = biphenyl-2-ol + sulfite. GO:0018742 epoxide hydrolase B activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018742 EC:3.3.2.-|UM-BBD_enzymeID:e0051 Catalysis of the hydrolysis of the ether in chloro- or hydroxyepoxypropane to produce chloropropane diol or glycerol. Acts on R enantiomers. GO:0018741 alkyl sulfatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018741 EC:3.1.6.-|UM-BBD_reactionID:r0602 alkyl sulphatase activity Catalysis of the reaction: dodecyl sulfate + H2O = sulfate + H+ + 1-dodecanol. GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004118 Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is increased in the presence of cGMP. GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004117 Reactome:R-HSA-111955 Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is regulated by calmodulin. GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004119 Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is decreased in the presence of cGMP. GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004114 EC:3.1.4.17|RHEA:14653|MetaCyc:3.1.4.17-RXN|Reactome:R-HSA-162425 3',5' cyclic-nucleotide phosphodiesterase activity|nucleoside-3',5-monophosphate phosphodiesterase activity|3': 5'-monophosphate phosphodiesterase (cyclic CMP) activity|3',5'-nucleotide phosphodiesterase activity|cyclic AMP phosphodiesterase activity|cyclic 3',5-nucleotide monophosphate phosphodiesterase activity|cytidine 3':5'-monophosphate phosphodiesterase (cyclic CMP) activity|cyclic 3',5'-phosphodiesterase activity|cyclic nucleotide phosphodiesterase activity|cyclic 3',5'-nucleotide phosphodiesterase activity|nucleoside 3',5'-cyclic phosphate diesterase activity|3',5'-cyclonucleotide phosphodiesterase activity|cyclic 3',5'-mononucleotide phosphodiesterase activity|PDE|3':5'-cyclic nucleotide 5'-nucleotidohydrolase activity|3', 5'-cyclic nucleoside monophosphate phosphodiesterase activity|3',5'-cyclic-nucleotide 5'-nucleotidohydrolase activity Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate. GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004113 EC:3.1.4.37|RHEA:14489|MetaCyc:3.1.4.37-RXN cyclic-CMP phosphodiesterase activity|2',3'-cyclic nucleotide 3'-phosphohydrolase activity|2',3'-cyclic nucleotide 3'-phosphodiesterase activity|cyclic 2',3'-nucleotide 3'-phosphodiesterase activity|2',3'-cyclic nucleotide phosphohydrolase|CNPase activity|cyclic 2',3'-nucleotide phosphodiesterase|nucleoside-2',3'-cyclic-phosphate 2'-nucleotidohydrolase activity|2',3'-cyclic AMP phosphodiesterase activity|2':3'-cyclic nucleotide 3'-phosphodiesterase activity|2',3'-cyclic nucleoside monophosphate phosphodiesterase|2':3'-CNMP-3'-ase activity Catalysis of the reaction: nucleoside 2',3'-cyclic phosphate + H2O = nucleoside 2'-phosphate. GO:0004116 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004116 CHEBI:100147 nalidixic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_100147 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004115 Reactome:R-HSA-9644869|Reactome:R-HSA-9705507|Reactome:R-HSA-9629675|MetaCyc:RXN0-5038|Reactome:R-HSA-111962|EC:3.1.4.53|RHEA:25277|Reactome:R-HSA-418553 3',5'-cyclic-AMP-specific phosphodiesterase activity|3',5'-cAMP-specific phosphodiesterase activity|adenosine 3',5'-cyclophosphate-specific phosphodiesterase activity|cAMP-specific phosphodiesterase activity|cyclic AMP-specific phosphodiesterase activity|3',5' cAMP-specific phosphodiesterase activity Catalysis of the reaction: adenosine 3',5'-cyclic phosphate + H2O = adenosine 5'-phosphate. GO:0004110 corticosteroid side-chain-isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004110 MetaCyc:CORTICOSTEROID-SIDE-CHAIN-ISOMERASE-RXN|EC:5.3.1.21|KEGG_REACTION:R04165|RHEA:17861 11-deoxycorticosterone aldose-ketose-isomerase activity|11-deoxycorticosterone ketol-isomerase activity Catalysis of the reaction: 11-deoxycorticosterone = 20-hydroxy-3-oxopregn-4-en-21-al. GO:0004112 cyclic-nucleotide phosphodiesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004112 Catalysis of the reaction: a nucleoside cyclic phosphate + H2O = a nucleoside phosphate. GO:0004111 creatine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004111 Reactome:R-HSA-200326|KEGG_REACTION:R01881|Reactome:R-HSA-200318|EC:2.7.3.2|RHEA:17157|MetaCyc:CREATINE-KINASE-RXN MiMi-CK|CK-MB|creatine phosphokinase activity|Mi-CK|creatine phosphotransferase activity|ATP:creatine N-phosphotransferase activity|ATP:creatine phosphotransferase activity|BB-CK|MM-CK|adenosine triphosphate-creatine transphosphorylase activity|CK|CK-BB|CK-MM|CKMiMi|MB-CK|phosphocreatine kinase activity Catalysis of the reaction: ATP + creatine = N-phosphocreatine + ADP + 2 H(+). GO:0102700 alpha-thujene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102700 MetaCyc:RXN-5105 Catalysis of the reaction: geranyl diphosphate(3-) <=> alpha-thujene + diphosphoric acid. GO:0102702 2-carene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102702 MetaCyc:RXN-5122 Catalysis of the reaction: geranyl diphosphate <=> (+)-2-carene + diphosphoric acid. GO:0102701 tricyclene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102701 MetaCyc:RXN-5121|RHEA:32687|EC:4.2.3.105 Catalysis of the reaction: geranyl diphosphate(3-) <=> tricyclene + diphosphoric acid. GO:0018759 methenyltetrahydromethanopterin cyclohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018759 UM-BBD_reactionID:r0347|EC:3.5.4.27|KEGG_REACTION:R03464|MetaCyc:3.5.4.27-RXN|RHEA:19053 5,10-methenyltetrahydromethanopterin cyclohydrolase activity|N5,N10-methenyltetrahydromethanopterin cyclohydrolase activity|methenyl-H4MPT cyclohydrolase activity|methenyl-H(4)MPT cyclohydrolase activity|5,10-methenyltetrahydromethanopterin 10-hydrolase (decyclizing) Catalysis of the reaction: 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H(2)O = N(5)-formyl-5,6,7,8-tetrahydromethanopterin + H(+). GO:0102704 GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102704 EC:2.4.1.257|MetaCyc:RXN-5463|RHEA:29519 Catalysis of the reaction: GDP-alpha-D-mannose(2-) + a (mannosyl)2-(N-acetylglucosaminyl)2-diphosphodolichol <=> H+ + GDP(3-) + a (mannosyl)3-(N-acetylglucosaminyl)2-diphosphodolichol. CHEBI:138735 1-[(9Z)-octadecenyl]-2,3-dioleoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138735 GO:0102703 camphene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102703 RHEA:25484|MetaCyc:RXN-5142|EC:4.2.3.117 Catalysis of the reaction: geranyl diphosphate <=> (-)-camphene + diphosphoric acid. GO:0018758 2,4-dihydroxy-6-(N'-ethyl)amino-1,3,5-triazine aminohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018758 UM-BBD_reactionID:r0122 Catalysis of the reaction: 2,4-dihydroxy-6-(N'-ethyl)amino-1,3,5-triazine + H2O = CH3CH2NH2 + cyanuric acid. CHEBI:138734 1-[(9Z)-octadecenyl]monooleoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138734 GO:0102706 butein:oxygen oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102706 EC:1.21.3.6|MetaCyc:RXN-6242|RHEA:34203 Catalysis of the reaction: butein 4'-beta-D-glucoside + O2 = aureusidin 6-O-beta-glucoside + H2O + H+. CHEBI:138733 alpha-D-galactosyl ditrans,octacis-undecaprenyl diphosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138733 GO:0102705 serine decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102705 MetaCyc:RXN-5641|RHEA:45824 Catalysis of the reaction: H+ + L-serine <=> ethanolaminium(1+) + carbon dioxide. CHEBI:138732 3',5'-dimethoxyflavone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138732 GO:0102708 S-adenosyl-L-methionine:N-methyl-beta-alanine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102708 MetaCyc:RXN-6462 Catalysis of the reaction: N-methyl-beta-alanine + S-adenosyl-L-methionine = H+ + N,N-dimethyl-beta-alanine + S-adenosyl-L-homocysteine. GO:0018755 2-chloro-4-hydroxy-6-amino-1,3,5-triazine aminohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018755 Catalysis of the reaction: 2-chloro-4-hydroxy-6-amino-1,3,5-triazine + OH- = 2,4-dihydroxy-6-amino-1,3,5-triazine + Cl-. GO:0018754 ammelide aminohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018754 MetaCyc:RXN-8017 Catalysis of the reaction: ammelide + H2O = cyanuric acid + NH3. GO:0102707 S-adenosyl-L-methionine:beta-alanine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102707 EC:2.1.1.49|MetaCyc:RXN-6461 Catalysis of the reaction: beta-alanine + S-adenosyl-L-methionine = H+ + N-methyl-beta-alanine + S-adenosyl-L-homocysteine. GO:0018757 deisopropylhydroxyatrazine aminohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018757 UM-BBD_reactionID:r0121|KEGG_REACTION:R05574 Catalysis of the reaction: deisopropylhydroxyatrazine + H2O = NH3 + 2,4-dihydroxy-6-(N'-ethyl)amino-1,3,5-triazine. GO:0102709 S-adenosyl-L-methionine:N,N-dimethyl-beta-alanine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102709 MetaCyc:RXN-6464 Catalysis of the reaction: N,N-dimethyl-beta-alanine + S-adenosyl-L-methionine = H+ + beta-alanine betaine + S-adenosyl-L-homocysteine. GO:0018756 ammeline aminohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018756 RHEA:26201|MetaCyc:RXN-8016 Catalysis of the reaction: ammeline + H2O = ammelide + NH3. CHEBI:6923 miconazole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_6923 GO:0018751 3,5-dichlorophenylcarboximide hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018751 UM-BBD_reactionID:r0707 Catalysis of the reaction: 3,5-dichlorophenylcarboximide + OH- = (3,5-dichlorophenylurea)acetate. GO:0018750 biuret amidohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018750 RHEA:17525|EC:3.5.1.84|UM-BBD_reactionID:r0846 Catalysis of the reaction: biuret + H2O = urea + CO2 + NH3. GO:0018753 cyanuric acid amidohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018753 MetaCyc:R468-RXN|EC:3.5.2.15|RHEA:14641|UM-BBD_reactionID:r0116 Catalysis of the reaction: cyanuric acid + H2O = biuret + CO2. GO:0018752 epsilon-caprolactam lactamase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018752 MetaCyc:R561-RXN|UM-BBD_reactionID:r0448 Catalysis of the reaction: epsilon-caprolactam + H2O = H+ + 6-aminohexanoate. CHEBI:138731 5'-hydroxy-3'-methoxyflavone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138731 CHEBI:138730 3'-methoxyflavones biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138730 CHEBI:44576 2'-hydroxybiphenyl-2-sulfinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_44576 GO:0018729 propionate CoA-transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018729 RHEA:23520|EC:2.8.3.1|MetaCyc:PROPIONATE-COA-TRANSFERASE-RXN|UM-BBD_reactionID:r0087 propionyl CoA:acetate CoA transferase activity|acetyl-CoA:propanoate CoA-transferase activity|propionate coenzyme A-transferase activity|propionate-CoA:lactoyl-CoA transferase activity|propionyl-CoA transferase activity Catalysis of the reaction: acetyl-CoA + propanoate = acetate + propanoyl-CoA. GO:0018726 9-phenanthrol sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018726 UM-BBD_reactionID:r0564 9-phenanthrol sulphotransferase activity Catalysis of the reaction: 9-phenanthrol + X-SO3(-) = HX + 9-phenanthrylsulfate. GO:0018725 trans-3,4-dihydrodiolphenanthrene sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018725 UM-BBD_reactionID:r0558 trans-3,4-dihydrodiolphenanthrene sulphotransferase activity Catalysis of the reaction: trans-3,4-dihydrodiolphenanthrene + 2 X-SO3(-) = 2 HX + phenanthrene-3,4-dihydrodiolsulfate conjugate. GO:0018728 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018728 GO:0018727 2-phenanthrol sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018727 UM-BBD_reactionID:r0563 2-phenanthrol sulphotransferase activity Catalysis of the reaction: 2-phenanthrol + X-SO3(-) = HX + 2-phenanthrylsulfate. GO:0018722 1-phenanthrol sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018722 UM-BBD_reactionID:r0565 1-phenanthrol sulphotransferase activity Catalysis of the reaction: 1-phenanthrol + X-SO3(-) = HX + 1-phenanthrylsulfate. GO:0018721 trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018721 UM-BBD_reactionID:r0559 trans-9R,10R-dihydrodiolphenanthrene sulphotransferase activity Catalysis of the reaction: trans-9R,10R-dihydrodiolphenanthrene + 2 X-SO3(-) = 2 HX + phenanthrene-9,10-dihydrodiolsulfate conjugate. GO:0018724 4-phenanthrol sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018724 UM-BBD_reactionID:r0562 4-phenanthrol sulphotransferase activity Catalysis of the reaction: 4-phenanthrol + X-SO3(-) = HX + 4-phenanthrylsulfate. CHEBI:138704 13-cis-retinyl tetradecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138704 GO:0018723 3-phenanthrol sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018723 UM-BBD_reactionID:r0561 3-phenanthrol sulphotransferase activity Catalysis of the reaction: 3-phenanthrol + X-SO3(-) = HX + 3-phenanthrylsulfate. GO:0018720 phenol kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018720 UM-BBD_reactionID:r0155|MetaCyc:PHENOLPHOS-RXN Catalysis of the reaction: phenol + X-HPO3- = XH + phenylphosphate. CHEBI:138718 all-trans-retinyl tetradecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138718 GO:0018737 2-ketocyclohexane-1-carboxyl-CoA hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018737 UM-BBD_reactionID:r0193 Catalysis of the reaction: 2-ketocyclohexane-1-carboxyl-CoA + H2O = pimeloyl-CoA. GO:0018736 6-oxo-2-hydroxycyclohexane-1-carboxyl-CoA hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018736 UM-BBD_reactionID:r0206 Catalysis of the reaction: 6-oxo-2-hydroxycyclohexane-1-carboxyl-CoA + H2O = 3-hydroxypimeloyl-CoA. GO:0018739 4-hydroxybenzoyl-CoA thioesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018739 RHEA:11948|EC:3.1.2.23|KEGG_REACTION:R01301|UM-BBD_reactionID:r0141|MetaCyc:3.1.2.23-RXN 4-hydroxybenzoyl-CoA hydrolase activity|4-hydroxybenzoyl-CoA thiolesterase activity Catalysis of the reaction: 4-hydroxybenzoyl-CoA + H(2)O = 4-hydroxybenzoate + CoA + H(+). GO:0018738 S-formylglutathione hydrolase activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0018738 KEGG_REACTION:R00527|EC:3.1.2.12|MetaCyc:S-FORMYLGLUTATHIONE-HYDROLASE-RXN|UM-BBD_reactionID:r0241|RHEA:14961|Reactome:R-HSA-5693724 Catalysis of the reaction: S-formylglutathione + H(2)O = formate + glutathione + H(+). GO:0018733 3,4-dihydrocoumarin hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018733 EC:3.1.1.35|UM-BBD_reactionID:r0419 Catalysis of the reaction: 3,4-dihydrocoumarin + H2O = 3-(2-hydroxyphenyl) propionate. GO:0018732 sulfolactone hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018732 UM-BBD_reactionID:r0583|EC:3.1.1.92 sulpholactone hydrolase activity Catalysis of the reaction: 4-sulfolactone + OH- = HSO3(-) + maleylacetate. GO:0018735 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018735 GO:0018734 butyrolactone hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018734 UM-BBD_reactionID:r0016 Catalysis of the reaction: butyrolactone + H2O = 4-hydroxybutanoate. GO:0018731 1-oxa-2-oxocycloheptane lactonase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018731 UM-BBD_reactionID:r0167 Catalysis of the reaction: 1-oxa-2-oxocycloheptane + H2O = 6-hydroxyhexanoate. GO:0018730 glutaconate CoA-transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018730 RHEA:23208|EC:2.8.3.12|UM-BBD_reactionID:r0085|MetaCyc:GLUTACONATE-COA-TRANSFERASE-RXN acetyl-CoA:(E)-glutaconate CoA-transferase activity Catalysis of the reaction: acetyl-CoA + (E)-glutaconate = acetate + glutaconyl-1-CoA. CHEBI:44557 nitrilotriacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_44557 GO:0018708 thiol S-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018708 EC:2.1.1.9|RHEA:18277|MetaCyc:THIOL-S-METHYLTRANSFERASE-RXN|Reactome:R-HSA-175976|UM-BBD_enzymeID:e0146 TMT|thiol methyltransferase activity|S-adenosyl-L-methionine:thiol S-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + a thiol = S-adenosyl-L-homocysteine + a thioether. GO:0018707 1-phenanthrol methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018707 UM-BBD_reactionID:r0493 Catalysis of the reaction: 1-phenanthrol + X-CH3 = X + 1-methoxyphenanthrene. CHEBI:741548 ethylmalonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_741548 GO:0018709 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018709 GO:0018704 obsolete 5-chloro-2-hydroxymuconic semialdehyde dehalogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018704 5-chloro-2-hydroxymuconic semialdehyde dehalogenase activity OBSOLETE. Catalysis of the reaction: 5-chloro-2-hydroxymuconic semialdehyde + H+ + 2 e- = Cl- + 2-hydroxymuconic semialdehyde. GO:0018703 2,4-dichlorophenoxyacetate dehalogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018703 UM-BBD_reactionID:r0280 Catalysis of the reaction: 2,4-dichlorophenoxyacetic acid + H+ + 2 e- = Cl- + 4-chlorophenoxyacetate. GO:0018706 pyrogallol hydroxytransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018706 RHEA:21000|EC:1.97.1.2|UM-BBD_reactionID:r0006|MetaCyc:1.97.1.2-RXN 1,2,3,5-tetrahydroxybenzene:1,2,3-trihydroxybenzene hydroxytransferase activity|1,2,3,5-tetrahydroxybenzene:1,2,3-trihydroxybenzene hydroxyltransferase activity|1,2,3,5-tetrahydroxybenzene hydroxyltransferase activity|pyrogallol hydroxyltransferase activity|1,2,3,5-tetrahydroxybenzene:pyrogallol transhydroxylase activity|1,2,3,5-tetrahydroxybenzene-pyrogallol hydroxyltransferase (transhydroxylase)|transhydroxylase activity Catalysis of the reaction: 1,2,3,5-tetrahydroxybenzene + 1,2,3-trihydroxybenzene = 1,3,5-trihydroxybenzene + 1,2,3,5-tetrahydroxybenzene. GO:0018705 1,2-dichloroethene reductive dehalogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018705 UM-BBD_enzymeID:e0272 1,2-dichloroethylene reductive dehalogenase activity Catalysis of the reaction: 1,2-dichloroethene + 2 H+ + 2 e- = HCl + vinyl chloride. GO:0018700 2-chloro-N-isopropylacetanilide reductive dehalogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018700 UM-BBD_reactionID:r0719|EC:1.97.1.- Catalysis of the reaction: 2-chloro-N-isopropylacetanilide + H+ + 2 e- = Cl- + N-isopropylacetanilide. GO:0018702 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene dehalogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018702 EC:1.97.1.-|UM-BBD_reactionID:r0440 1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene dehalogenase activity|DDE dehalogenase activity Catalysis of the reaction: 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene + H+ + 2 e- = Cl- + 1-chloro-2,2-bis(4-chlorophenyl)ethene. 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene is also known as DDE; 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU. GO:0018701 2,5-dichlorohydroquinone reductive dehalogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018701 EC:1.97.1.-|UM-BBD_enzymeID:e0366 Catalysis of the reaction: organohalide + 2 H+ + 2 e- = R-H + HCl. Reactants include chlorohydroquinone (forms hydroquinone) and 2,5-dichlorohydroquinone (forms chlorohydroquinone). GO:0018719 6-aminohexanoate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018719 UM-BBD_reactionID:r0449|MetaCyc:R562-RXN Catalysis of the reaction: 6-aminohexanoate + alpha-ketoglutarate = glutamate + 6-oxohexanoate. GO:0018718 1,2-dihydroxy-phenanthrene glycosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018718 UM-BBD_reactionID:r0569 Catalysis of the reaction: 1,2-dihydroxyphenanthrene + UDP-glucose = 2-hydroxy-1-phenanthryl-beta-D-glucopyranoside + UDP. GO:0018715 9-phenanthrol UDP-glucuronosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018715 UM-BBD_reactionID:r0567 Catalysis of the reaction: 9-phenanthrol + UDP-glucuronate = 9-phenanthryl-beta-D-glucuronide + UDP. GO:0018714 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018714 GO:0018717 9-phenanthrol glycosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018717 UM-BBD_reactionID:r0511 Catalysis of the reaction: 9-phenanthrol + glucose = 9-phenanthryl-beta-D-glucopyranoside + H2O. GO:0018716 1-phenanthrol glycosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018716 UM-BBD_reactionID:r0525 Catalysis of the reaction: 1-phenanthrol + glucose = 1-phenanthryl-beta-D-glucopyranoside + H2O. GO:0018711 benzoyl acetate-CoA thiolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018711 UM-BBD_reactionID:r0243|MetaCyc:RXN-1305 Catalysis of the reaction: benzoyl acetyl-CoA + CoA = acetyl-CoA + benzoyl-CoA. GO:0018710 acetone carboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018710 MetaCyc:6.4.1.6-RXN|KEGG_REACTION:R05735|EC:6.4.1.6|RHEA:18385 acetone:carbon-dioxide ligase (AMP-forming) Catalysis of the reaction: acetone + ATP + CO(2) + 2 H(2)O = acetoacetate + AMP + 4 H(+) + 2 phosphate. CHEBI:44549 4-amino-5-aminomethyl-2-methylpyrimidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_44549 GO:0018713 3-ketopimelyl-CoA thiolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018713 MetaCyc:RXN-8032|UM-BBD_reactionID:r0197 Catalysis of the reaction: 3-ketopimeloyl-CoA + CoA = glutaryl-CoA + acetyl-CoA. GO:0018712 3-hydroxybutyryl-CoA thiolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018712 MetaCyc:R7-RXN|UM-BBD_reactionID:r0010 Catalysis of the reaction: 3-hydroxy-5-oxohexanoyl-CoA + CoASH = 3-hydroxybutyryl-CoA + acetyl-CoA. GO:0102511 pelargonidin 3-O-glucoside 7-O-glucosyltransferase (acyl-glucose dependent) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102511 EC:2.4.1.300|MetaCyc:RXN-14440 Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + 1-O-vanilloyl-beta-D-glucose <=> pelargonidin 3,7-di-O-beta-D-glucoside + vanillate + H+. GO:0102510 pelargonidin 3-O-glucoside 5-O-glucosyltransferase (acyl-glucose dependent) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102510 EC:2.4.1.299|MetaCyc:RXN-14439 Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + 1-O-vanilloyl-beta-D-glucose <=> anthocyanidin 3,5-di-O-beta-D-glucoside + vanillate + H+. GO:0102513 delphinidin 3-O-glucoside 5-O-glucosyltransferase (vanilloyl-glucose dependent) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102513 MetaCyc:RXN-14442 Catalysis of the reaction: delphinidin 3-O-beta-D-glucoside + 1-O-vanilloyl-beta-D-glucose <=> delphinidin 3,7-di O-beta-D-glucoside + vanillate + H+. GO:0102512 delphinidin 3-O-glucoside 5-O-glucosyltransferase (acyl-glucose dependent) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102512 EC:2.4.1.299|MetaCyc:RXN-14441 Catalysis of the reaction: delphinidin 3-O-beta-D-glucoside + 1-O-vanilloyl-beta-D-glucose <=> delphinidin 3-O-beta-D-glucoside-5-O-beta-D-glucoside betaine + vanillate + H+. GO:0102515 pelargonidin 3-O-glucoside 7-O-glucosyltransferase (feruloyl-glucose dependent) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102515 MetaCyc:RXN-14447 Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + 1-O-feruloyl-beta-D-glucose <=> pelargonidin 3,7-di-O-beta-D-glucoside + ferulate + H+. GO:0102514 cyanidin 3-O-glucoside 7-O-glucosyltransferase (feruloyl-glucose dependent) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102514 EC:2.4.1.300|MetaCyc:RXN-14446 Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-feruloyl-beta-D-glucose <=> cyanidin 3,7-di-O-beta-D-glucoside betaine + ferulate + H+. PO:0030056 archesporial cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0030056 sporogenous cell (exact)|胞原細胞 (Japanese, exact)|archesporial initial (exact)|célula arquesporial (Spanish, exact) A native plant cell (PO:0025606) that divides to gives rise to a sporocyte (PO:0006204) and is part of a sporangium (PO:0025094). GO:0102517 oleate 12-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102517 MetaCyc:RXN-14487 Catalysis of the reaction: oleoyl-CoA + NADH + O2 + H+ = ricinoleyl-CoA + NAD + H2O. GO:0102516 delphinidin 3-O-glucoside 7-O-glucosyltransferase (feruloyl-glucose dependent) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102516 MetaCyc:RXN-14448 Catalysis of the reaction: delphinidin 3-O-beta-D-glucoside + 1-O-feruloyl-beta-D-glucose <=> delphinidin 3,7-di O-beta-D-glucoside + ferulate + H+. GO:0102518 (11Z)-eicosenoate 14-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102518 EC:1.14.18.4|MetaCyc:RXN-14488 Catalysis of the reaction: (11Z)-eicosenoyl-CoA + NADH + O2 + H+ = lesqueroloyl-CoA + NAD + H2O. GO:0102520 L-threonine O-3-phosphate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102520 MetaCyc:RXN-14505 Catalysis of the reaction: O-phospho-L-threonine + H2O = L-threonine + hydrogenphosphate. GO:0102522 tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102522 RHEA:36355|EC:2.5.1.114|MetaCyc:RXN-14518 Catalysis of the reaction: S-adenosyl-L-methionine + 4-demethylwyosine37 in tRNAPhe <=> 5'-S-methyl-5'-thioadenosine + H+ + 7-[(3S)-3-amino-3-carboxypropyl]-4-demethylwyosine37 in tRNAPhe. GO:0102521 tRNA-4-demethylwyosine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102521 EC:4.1.3.44|RHEA:36347|MetaCyc:RXN-14516 Catalysis of the reaction: pyruvate + S-adenosyl-L-methionine + N1-methylguanine37 in tRNAPhe = L-methionine + 5'-deoxyadenosine + carbon dioxide + H2O + 4-demethylwyosine37 in tRNAPhe. GO:0102524 tRNAPhe (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102524 EC:1.14.11.42|RHEA:37899|MetaCyc:RXN-14538 Catalysis of the reaction: 2-oxoglutarate + O2 + 7-[(3S)-(3-amino-3-carboxypropyl)]-wyosine37 in tRNAPhe = succinate + carbon dioxide + 7-(2-hydroxy-3-amino-3-carboxypropyl)-wyosine37 in tRNAPhe. GO:0102523 2-chloroacrylate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102523 EC:1.3.1.103|RHEA:36591|MetaCyc:RXN-14536 Catalysis of the reaction: (S)-2-chloropropanoate + NADP <=> 2-chloroacrylate + NADPH + H+. GO:0102526 8-demethylnovobiocic acid C8-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102526 EC:2.1.1.284|MetaCyc:RXN-14543|RHEA:36651 Catalysis of the reaction: S-adenosyl-L-methionine + 8-desmethylnovobiocic acid <=> S-adenosyl-L-homocysteine + novobiocic acid + H+. GO:0102525 2-oxoglutarate, L-arginine oxygenase (succinate-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102525 MetaCyc:RXN-14542|EC:1.14.11.41|RHEA:36607 Catalysis of the reaction: L-argininium(1+) + 2-oxoglutarate + O2 = (3S)-3-hydroxy-L-arginine(1+) + succinate + carbon dioxide. GO:0102528 7,8,4'-trihydroxyflavone methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102528 MetaCyc:RXN-14658 Catalysis of the reaction: S-adenosyl-L-methionine + 7,8,4'-trihydroxyflavone <=> H+ + S-adenosyl-L-homocysteine + 7,4'-dihydroxy, 8-methoxyflavone. GO:0102527 8-demethylnovobiocate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102527 EC:6.3.1.15|RHEA:36699|MetaCyc:RXN-14547 Catalysis of the reaction: 3-amino-4,7-dihydroxycoumarin + 3-dimethylallyl-4-hydroxybenzoate + ATP(4-) <=> H+ + 8-desmethylnovobiocic acid(1-) + AMP(2-) + diphosphoric acid. GO:0102529 apigenin 7-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102529 MetaCyc:RXN-14661 Catalysis of the reaction: S-adenosyl-L-methionine + apigenin-7-olate <=> S-adenosyl-L-homocysteine + genkwanin. PO:0030073 exothecium biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0030073 epithecium (exact)|sporangium wall exothecium (exact)|sporangium epidermis (exact)|葯の表皮（外膜) (Japanese, exact)|exotecio (Spanish, exact) A portion of epidermis (PO:0005679) that is the outermost layer of a sporangium wall (PO:0025306). GO:0102531 ecdysteroid-phosphate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102531 MetaCyc:RXN-14734 Catalysis of the reaction: H2O + an ecdysteroid 22-phosphate <=> hydrogenphosphate + an ecdysteroid. GO:0102530 aclacinomycin T methylesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102530 RHEA:37891|MetaCyc:RXN-14703|EC:3.1.1.95 Catalysis of the reaction: aclacinomycin T(1+) + H2O <=> 15-demethylaclacinomycin T + methanol + H+. GO:0102533 genkwanin 4'-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102533 MetaCyc:RXN-14750 Catalysis of the reaction: genkwanin + S-adenosyl-L-methionine <=> H+ + apigenin-7,4'-dimethyl ether + S-adenosyl-L-homocysteine. GO:0102532 genkwanin 6-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102532 MetaCyc:RXN-14748 Catalysis of the reaction: genkwanin + O2 + NADPH + H+ <=> scutellarein 7-methyl ether + H2O + NADP. GO:0102535 ladanein 6-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102535 MetaCyc:RXN-14752 Catalysis of the reaction: ladanein + S-adenosyl-L-methionine <=> H+ + salvigenin + S-adenosyl-L-homocysteine. GO:0102534 apigenin-7,4'-dimethyl ether 6-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102534 MetaCyc:RXN-14751 Catalysis of the reaction: apigenin-7,4'-dimethyl ether + O2 + NADPH + H+ <=> ladanein + H2O + NADP. GO:0102537 ecdysone-phosphate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102537 MetaCyc:RXN-14766 Catalysis of the reaction: ecdysone 22-phosphate + H2O <=> ecdysone + hydrogenphosphate. GO:0102536 sakuranetin 6-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102536 MetaCyc:RXN-14754 Catalysis of the reaction: sakuranetin + O2 + NADPH + H+ <=> carthamidin-7-methyl ether + H2O + NADP. GO:0102539 UDP-N-acetyl-alpha-D-fucosamine dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102539 MetaCyc:RXN-14769 Catalysis of the reaction: UDP-N-acetyl-alpha-D-fucosamine + NAD(P) = UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose + H+ + NAD(P)H. GO:0102538 UDP-N-acetyl-alpha-D-quinovosamine dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102538 MetaCyc:RXN-14767 Catalysis of the reaction: UDP-N-acetyl-alpha-D-quinovosamine + NAD(P) = UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose + H+ + NAD(P)H. CHEBI:6750 (+)-menthofuran biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_6750 GO:0102540 D-mannose 6-phosphate 1-epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102540 MetaCyc:RXN-14815 Catalysis of the reaction: alpha-D-mannose 6-phosphate = beta-D-mannose 6-phosphate. GO:0102542 aclacinomycin A methylesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102542 EC:3.1.1.95|MetaCyc:RXN-14863 Catalysis of the reaction: aclacinomycin A + H2O <=> 15-demethoxy-aclacinomycin A + methanol + H+. GO:0102541 D-galactose 6-phosphate 1-epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102541 MetaCyc:RXN-14816 Catalysis of the reaction: alpha-D-galactose 6-phosphate = beta-D-galactose 6-phosphate. GO:0102544 ornaline synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102544 MetaCyc:RXN-14880 Catalysis of the reaction: L-ornithinium(1+) + 2-oxoglutarate + NADPH + H+ <=> ornaline + NADP + H2O. GO:0102543 epsilon-rhodomycinone methylesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102543 EC:3.1.1.95|MetaCyc:RXN-14865 Catalysis of the reaction: epsilon-rhodomycinone + H2O <=> 15-demethoxy-epsilon-rhodomycinone + methanol + H+. GO:0102546 mannosylglycerate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102546 RHEA:58456|MetaCyc:RXN-14900 Catalysis of the reaction: H2O + 2-(alpha-D-mannosyl)-D-glycerate <=> alpha-D-mannose + D-glycerate. GO:0102545 phosphatidyl phospholipase B activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102545 EC:3.1.1.5|MetaCyc:RXN-14899 Catalysis of the reaction: 2 H2O + a phosphatidylcholine = sn-glycero-3-phosphocholine + 2 H+ + 2 a carboxylate. GO:0102547 glucosylglycerate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102547 RHEA:32059|MetaCyc:RXN-14901 Catalysis of the reaction: H2O + 2-O-(alpha-D-glucopyranosyl)-D-glycerate <=> alpha-D-glucose + D-glycerate. GO:0102549 1-18:1-2-16:0-monogalactosyldiacylglycerol lipase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102549 EC:3.1.1.26|MetaCyc:RXN-14912 Catalysis of the reaction: 1-18:1-2-16:0-monogalactosyldiacylglycerol + H2O <=> sn-1-lyso-2-16:0-monogalactosyldiacylglycerol + oleate + H+. GO:0004289 obsolete subtilase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004289 subtilase activity OBSOLETE. Was not defined before being made obsolete. GO:0004286 obsolete proprotein convertase 2 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004286 NEC 2 activity|PC2 activity|proprotein convertase 2 activity|neuroendocrine convertase 2 activity|prohormone convertase II activity OBSOLETE. Catalysis of the release of protein hormones and neuropeptides from their precursors, generally by cleavage of -Lys-Arg-Xaa at the Arg-Xaa bond. GO:0004285 obsolete proprotein convertase 1 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004285 NEC 1 activity|prohormone convertase 3|PC1 activity|proprotein convertase 1 activity|neuroendocrine convertase 1 activity|prohormone convertase I activity OBSOLETE. Catalysis of the release of protein hormones, neuropeptides and renin from their precursors, generally by cleavage of -Lys-Arg-Xaa at the Arg-Xaa bond. GO:0004287 obsolete prolyl oligopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004287 prolyl oligopeptidase activity|endoprolylpeptidase activity|prolyl endopeptidase activity|post-proline endopeptidase activity|post-proline cleaving enzyme activity|proline-specific endopeptidase activity|proline endopeptidase activity OBSOLETE. Catalysis of the hydrolysis of Pro-Xaa > Ala-Xaa in oligopeptides. GO:0004281 obsolete pancreatic elastase II activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004281 pancreatic elastase II activity|pancreatic elastase 2 OBSOLETE. Catalysis of the preferential cleavage of Leu-Xaa, Met-Xaa and Phe-Xaa. Hydrolyzes elastin. GO:0004284 obsolete acrosin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004284 acrosomal proteinase activity|beta-acrosin|acrosin activity|acrosomal protease activity|acrozonase activity|psi-acrosin|alpha-acrosin|acrosin amidase activity OBSOLETE. Catalysis of the preferential cleavage of Arg-Xaa > Lys-Xaa. GO:0004283 obsolete plasmin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004283 fibrinolysin activity|fibrinase activity|serum tryptase activity|plasmin activity|actase activity|thrombolysin OBSOLETE. Catalysis of the preferential cleavage of Lys-Xaa > Arg-Xaa; higher selectivity than trypsin. Converts fibrin into soluble products. GO:0004291 obsolete subtilisin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004291 savinase 8.0L|savinase 32.0 L EX|protin A 3L|colistinase activity|protease XXVII|savinase 16.0L|subtilisin GX|esperase activity|subtilisin E|subtilisin sendai|savinase activity|thermoase|subtilopeptidase activity|protease S|subtilisin BL|alcalase 0.6L|alcalase 2.5L|genenase I|bioprase AL 15|alcalase activity|bacillus subtilis alkaline proteinase bioprase activity|protease VIII|kazusase activity|thermoase PC 10|savinase 4.0T|bacillopeptidase B|superase activity|bioprase APL 30|bacillopeptidase A|subtilisin S41|bacillus subtilis alkaline proteinase activity|opticlean|maxatase activity|orientase 10B|subtilisin J|subtilisin DY|SP 266|ALK-enzyme|subtilisin activity OBSOLETE. Catalysis of the hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyzes peptide amides. GO:0004290 obsolete kexin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004290 Kex2-like precursor protein processing endoprotease|andrenorphin-Gly-generating enzyme|proteinase yscF activity|proteinase Kex2p|Kex2 protease|paired-basic endopeptidase activity|Kex2 endopeptidase|prohormone-processing proteinase activity|Kex2 proteinase|yeast KEX2 protease activity|endoproteinase Kex2p|protease KEX2|Kex2 endoprotease|Kex2-like endoproteinase|Kex2 endoproteinase|Kex 2p proteinase|yeast cysteine proteinase F|gene KEX2 dibasic proteinase|kexin activity|prohormone-processing KEX2 proteinase|prohormone-processing endoprotease activity OBSOLETE. Catalysis of the cleavage of the Arg-Xaa bond in Lys-Arg-Xaa and Arg-Arg-Xaa to process Yeast alpha-factor pheromone and killer toxin precursors. GO:0004297 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004297 GO:0004296 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004296 GO:0004299 obsolete proteasome endopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004299 multicatalytic endopeptidase|proteasome|proteasome endopeptidase complex|proteasome endopeptidase activity OBSOLETE. Catalysis of the cleavage at peptide bonds with very broad specificity. GO:0004298 threonine-type endopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004298 EC:3.4.25.- threonine endopeptidase activity|ingensin|tricorn protease|tricorn proteinase|26S protease|prosome|alkaline protease|multicatalytic proteinase (complex)|large multicatalytic protease|multicatalytic proteinase|proteasome endopeptidase complex|MCP|multicatalytic endopeptidase complex|lens neutral proteinase Catalysis of the hydrolysis of internal peptide bonds in a polypeptide chain by a mechanism in which the hydroxyl group of a threonine residue at the active center acts as a nucleophile. GO:0004293 obsolete tissue kallikrein activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004293 submaxillary kallikrein|pancreatic kallikrein|urinary kallikrein|tissue kallikrein activity|glumorin|submandibular kallikrein|onokrein P|urokallikrein|padreatin|depot-padutin|bradykininogenase|dilminal D|glandular kallikrein activity|padutin|kininogenase|kallidinogenase|kininogenin activity|kidney kallikrein|salivary kallikrein|callicrein OBSOLETE. Catalysis of the preferential cleavage of Arg-Xaa bonds in small molecule substrates. Highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-Xaa or Leu-Xaa. The rat enzyme is unusual in liberating bradykinin directly from autologous kininogens by cleavage at two Arg-Xaa bonds. GO:0004295 obsolete trypsin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004295 tripcellim|alpha-trypsin activity|pseudotrypsin|parenzyme|sperm receptor hydrolase activity|parenzymol|trypure|beta-trypsin activity|cocoonase activity|trypsin activity|tryptar OBSOLETE. Catalysis of the preferential cleavage of Arg-Xaa, Lys-Xaa. GO:0004294 obsolete tripeptidyl-peptidase II activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004294 TPP|tripeptidyl aminopeptidase II|tripeptidyl peptidase II|tripeptidyl-peptidase II activity|tripeptidyl aminopeptidase activity|tripeptidyl peptidase activity OBSOLETE. Catalysis of the release of an N-terminal tripeptide from a polypeptide at neutral pH. CHEBI:138792 1,2-di-[(9Z)-hexadecenoyl]-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138792 GO:0004263 obsolete chymotrypsin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004263 avazyme|quimotrase activity|chymotrypsins A and B|alpha-chymotrypsin activity|alpha-chymotrypsin A|quimar|alpha-chymar|enzeon|alpha-chymar ophth|chymotrypsin A activity|chymar|chymotrypsin B activity|chymotest|chymotrypsin activity OBSOLETE. Catalysis of the preferential cleavage of Tyr-Xaa > Trp-Xaa > Phe-Xaa > Leu-Xaa. GO:0004262 obsolete cerevisin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004262 yeast proteinase B activity|baker's yeast proteinase B|peptidase beta|proteinase yscB activity|brewer's yeast proteinase|cerevisin activity OBSOLETE. Catalysis of the hydrolysis of proteins with broad specificity, and of BZ-Arg-OET > Ac-Tyr-OET. Does not hydrolyze peptide amides. GO:0004261 obsolete cathepsin G activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004261 chymotrypsin-like proteinase activity|cathepsin G activity|neutral proteinase activity OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Specificity similar to chymotrypsin C. GO:0004279 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004279 GO:0004278 obsolete granzyme B activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004278 CCPII|CTLA1|cytotoxic t-lymphocyte proteinase 2 activity|granzyme B activity|CCP1 proteinase|cytotoxic cell proteinase-1|granzyme H|granzyme G OBSOLETE. Catalysis of the preferential cleavage of Asp-Xaa > Asn-Xaa > Met-Xaa, Ser-Xaa. GO:0004275 obsolete enteropeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004275 enteropeptidase activity|enterokinase activity OBSOLETE. Catalysis of the selective cleavage of Lys6-Ile7 bond in trypsinogen. GO:0004274 obsolete dipeptidyl-peptidase IV activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004274 EC:3.4.14.5|MetaCyc:3.4.14.5-RXN lymphocyte antigen CD26|X-PDAP|postproline dipeptidyl aminopeptidase IV|dipeptidyl aminopeptidase IV activity|glycylprolyl dipeptidylaminopeptidase activity|pep X|amino acyl-prolyl dipeptidyl aminopeptidase activity|leukocyte antigen CD26|dipeptidyl-peptidase IV activity|glycylproline aminopeptidase activity|Xaa-Pro-dipeptidylaminopeptidase activity|post-proline dipeptidyl aminopeptidase IV activity|dipeptidyl-aminopeptidase IV|DPP IV/CD26|glycoprotein GP110|dipeptidyl-peptide hydrolase activity|DPP IV activity|dipeptidyl peptidase IV|glycylprolyl aminopeptidase activity|Xaa-Pro-dipeptidyl-aminopeptidase activity|T cell triggering molecule Tp103|Gly-Pro naphthylamidase activity OBSOLETE. Catalysis of the release of an N-terminal dipeptide, by the hydrolysis of the Xbb-Xcc bond in Xaa-Xbb-Xcc, preferentially when Xbb is Pro, provided Xcc is neither Pro nor hydroxyproline. GO:0004277 obsolete granzyme A activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004277 T-cell derived serine proteinase|CTLA3|HuTPS|cytotoxic T-lymphocyte proteinase 1 activity|granzyme A activity|cytotoxic T lymphocyte serine protease|T-cell associated protease 1|TSP-1 OBSOLETE. Catalysis of the hydrolysis of proteins, including fibronectin, type IV collagen and nucleolin. Preferential cleavage: Arg-Xaa > Lys-Xaa > Phe-Xaa in small molecule substrates. GO:0102500 beta-maltose 4-alpha-glucanotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102500 MetaCyc:RXN-14354|EC:2.4.1.25 Catalysis of the reaction: beta-D-glucose + a plant soluble heteroglycan = a plant soluble heteroglycan + maltose. GO:0004276 obsolete furin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004276 PACE|SPC3|furin activity|paired basic amino acid converting enzyme|prohormone convertase activity|paired basic amino acid cleaving enzyme|serine proteinase PACE|paired basic amino acid residue cleaving enzyme activity|dibasic processing enzyme activity OBSOLETE. Catalysis of the release of mature proteins from their proproteins by cleavage of the terminal bond of Arg-Xaa-Yaa-Arg-Z motifs where Xaa can be any amino acid and Yaa is Arg or Lys. Releases albumin, complement component C3 and von Willebrand factor from their respective precursors. GO:0102502 ADP-glucose-starch glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102502 MetaCyc:RXN-14378|EC:2.4.1.242 Catalysis of the reaction: ADP alpha-D-glucoside + n a 1,4-alpha-D-glucan = ADP + n alpha-amylose. GO:0102501 D-fructuronate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102501 MetaCyc:RXN-14368 Catalysis of the reaction: D-mannonate + NADP = NADPH + H+ + D-fructuronate. GO:0102504 luteolinidin 5-O-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102504 MetaCyc:RXN-14424 Catalysis of the reaction: luteolinidin + UDP-alpha-D-glucose <=> luteolinidin 5-O-glucoside + UDP + 2 H+. GO:0102506 cyanidin 3-O-glucoside 5-O-glucosyltransferase (acyl-glucose dependent) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102506 MetaCyc:RXN-14432|EC:2.4.1.299 Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-feruloyl-beta-D-glucose = cyanin betaine + ferulate + H+. GO:0102505 apigeninidin 5-O-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102505 MetaCyc:RXN-14427 Catalysis of the reaction: apigeninidin + UDP-alpha-D-glucose <=> apigeninidin 5-O-glucoside + UDP + H+. GO:0004280 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004280 GO:0102508 cyanidin 3,7-diglucoside glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102508 MetaCyc:RXN-14435 Catalysis of the reaction: cyanidin 3,7-di-O-beta-D-glucoside betaine + H2O <=> cyanidin 3-O-beta-D-glucoside betaine + beta-D-glucose. GO:0102507 cyanidin 3-O-glucoside 7-O-glucosyltransferase (hydroxybenzoly-glucose dependent) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102507 MetaCyc:RXN-14434|EC:2.4.1.300 Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> cyanidin 3,7-di-O-beta-D-glucoside betaine + 4-hydroxybenzoic acid + H+. GO:0102509 cyanidin 3,5-diglucoside glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102509 MetaCyc:RXN-14436 Catalysis of the reaction: cyanin betaine + H2O <=> cyanidin 3-O-beta-D-glucoside betaine + beta-D-glucose. GO:0102591 delphinidin 7-O-glucoside acyltransferase (acyl-glucose dependent) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102591 MetaCyc:RXN-15352 Catalysis of the reaction: delphinidin 3-O-rutinoside-7-O-glucoside + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> delphinidin 3-O-rutinoside-7-O-(6-O-(p-hydroxybenzoyl)-glucoside) + beta-D-glucose. GO:0102590 delphinidin 3-O-rutinoside 7-O-glucosyltransferase (acyl-glucose dependent) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102590 MetaCyc:RXN-15351 Catalysis of the reaction: delphinidin 3-O-rutinoside + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> delphinidin 3-O-rutinoside-7-O-glucoside + 4-hydroxybenzoic acid + H+. GO:0102593 UDP-glucose: N-methylanthranilate glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102593 MetaCyc:RXN-15371 Catalysis of the reaction: N-methylanthranilate + UDP-alpha-D-glucose = N-methylanthraniloyl-beta-D-glucopyranose + UDP. GO:0102592 delphinidin 7-O-(6-O-(4-O-(glucosyl)-oxybenzoyl)-glucoside) acyltransferase (acyl-glucose dependent activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102592 MetaCyc:RXN-15354 Catalysis of the reaction: delphinidin 3-O-rutinoside-7-O-(6-O-(4-O-(glucosyl)-oxybenzoyl)-glucoside) + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> violdelphin + beta-D-glucose. GO:0102595 cyanidin 7-O-(6-O-(4-O-(glucosyl)-oxybenzoyl)-glucoside) acyltransferase (acyl-glucose dependent) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102595 MetaCyc:RXN-15374 Catalysis of the reaction: cyanidin 3-O-glucoside-7-O-(6-O-(4-O-(glucosyl)-oxybenzoyl)-glucoside) + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> cyanidin 3-O-glucoside-7-O-(6-O-(4-O-(6-O-(p-hydroxybenzoyl)-glucosyl)-oxybenzoyl)-glucoside) + beta-D-glucose. GO:0102594 cyanidin 7-O-glucoside acyltransferase(acyl-glucose dependent) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102594 MetaCyc:RXN-15372 Catalysis of the reaction: cyanidin 3,7-di-O-beta-D-glucoside betaine + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> cyanidin 3-O-glucoside-7-O-(6-O-(p-hydroxybenzoyl)-glucoside) + beta-D-glucose. GO:0043850 RecFOR complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043850 A heterotrimeric complex composed of the subunits RecF, RecO and RecR. Mediates the loading of RecA protein specifically onto SSB-coated gapped DNA during DNA repair. UBERON:0005192 deferent duct artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005192 arteria ductus deferentis|artery of ductus deferens|vas deferens artery|ductus deferens artery An artery in males that provides blood to the vas deferens. The artery usually arises from the anterior trunk of the superior vesical artery. It accompanies the vas deferens into the testis, where it anastomoses with the testicular artery. In this way it also supplies blood to the testis and epididymis. A small branch supplies the ureter[WP]. GO:0102597 3alpha-hydroxy-ent-sandaracopimardiene 9-beta-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102597 EC:1.14.14.122|RHEA:41468|MetaCyc:RXN-15381 Catalysis of the reaction: ent-sandaracopimaradien-3-beta-ol + NADPH + H+ + O2 <=> oryzalexin E + NADP + H2O. GO:0102596 cytochrome P450 dependent ent-sandaracopimaradiene 3-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102596 MetaCyc:RXN-15379|EC:1.14.14.70|RHEA:41464 Catalysis of the reaction: ent-sandaracopimara-8(14),15-diene + NADPH + H+ + O2 <=> ent-sandaracopimaradien-3beta-ol + NADP + H2O. GO:0043852 monomethylamine methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043852 RHEA:26059|EC:2.1.1.248|MetaCyc:RXN-8098 MMAMT|MtmB|monomethylamine:corrinoid methyltransferase activity Catalysis of the reaction: monomethylamine + a monomethylamine corrinoid protein = a methylated monomethylamine corrinoid protein + NH3. GO:0102599 cytochrome P450 dependent beta-amyrin 12,13beta-epoxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102599 MetaCyc:RXN-15383 Catalysis of the reaction: beta-amyrin + O2 + H+ + NAD(P)H <=> 12,13beta-epoxy-beta-amyrin + H2O + NAD(P). GO:0043851 methanol-specific methylcobalamin:coenzyme M methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043851 MetaCyc:RXN-8096 methanol-specific methylcobalamin: coenzyme M methyltransferase activity|methanol-specific methylcobalamin:CoM methyltransferase activity|MtaA|MT2|MtaC protein:coenzyme M methyltransferase activity|MtaC protein: coenzyme M methyltransferase activity|methyltransferase 2 Catalysis of the reaction: a methylated methanol corrinoid protein + coenzyme M = a methanol corrinoid protein + methyl-CoM. This reaction is the transfer of the methyl group from the methylated corrinoid cofactor of a methylamine corrinoid protein to coenzyme M. GO:0102598 3alpha-hydroxy-ent-sandaracopimardiene 7-beta-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102598 EC:1.14.14.123|MetaCyc:RXN-15382|RHEA:41472 Catalysis of the reaction: ent-sandaracopimaradien-3-beta-ol + NADPH + H+ + O2 <=> oryzalexin D + NADP + H2O. CHEBI:68465 2,6-dihydroxybenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68465 CHEBI:68464 4-(3-methylbut-2-enyl)-L-abrine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68464 GO:0043858 arginine:ornithine antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043858 ArcD|arginine-ornithine antiporter activity|arginine/ornithine antiporter activity Catalysis of the reaction: arginine(out) + ornithine(in) = arginine(in) + ornithine(out). GO:0043857 N-acetylornithine carbamoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043857 EC:2.1.3.9|KEGG_REACTION:R07245|RHEA:18609|MetaCyc:2.1.3.9-RXN carbamoyl-phosphate:N2-acetyl-L-ornithine carbamoyltransferase activity|N-acetylornithine transcarbamylase activity|acetylornithine transcarbamylase activity|AOTC|carbamoyl-phosphate:2-N-acetyl-L-ornithine carbamoyltransferase activity Catalysis of the reaction: N(2)-acetyl-L-ornithine + carbamoyl phosphate = N(2)-acetyl-L-citrulline + H(+) + phosphate. UBERON:0005199 cervical mammary gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005199 A mammary gland that is part of a cervical region. GO:0043859 obsolete cyanophycinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043859 cyanophycinase activity OBSOLETE. Catalysis of the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides. GO:0043854 cyclic nucleotide-gated mechanosensitive ion channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043854 cyclic nucleotide-regulated small mechanosensitive ion channel|cyclic nucleotide regulated mechanosensitive ion channel|cyclic nucleotide gated mechanosensitive ion channel activity|small conductance mechanosensitive ion channel|cyclic nucleotide-regulated mechanosensitive ion channel|MscS Enables the transmembrane transfer of an ion by a channel that opens in response to a mechanical stress and when a cyclic nucleotide has been bound by the channel complex or one of its constituent parts. UBERON:0005196 spleen germinal center biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005196 splenic germinal center|spleen GC|spleen follicle center|germinal center of spleen A germinal center that is part of the spleen. The spleen germinal center is located in a secondary B follicle in the white pulp of the spleen. GO:0043853 methanol-CoM methyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043853 MetaCyc:CPLX-421 methanol-coenzyme M methyltransferase complex|methanol: CoM methyltransferase complex|methanol:coenzyme M methyltransferase complex|methanol:CoM methyltransferase complex|methanol: coenzyme M methyltransferase complex A heterotrimeric protein complex composed of a methanol methyltransferase subunit, a corrinoid protein and a methanol-specific corrinoid:coenzyme M methyltransferase subunit. Catalyzes the transfer of a methyl group from methanol to coenzyme M as part of the pathway of methanogenesis from methanol. UBERON:0005195 deferent duct vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005195 A vein that is part of a vas deferens [Automatically generated definition]. GO:0043856 anti-sigma factor antagonist activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043856 anti-anti-sigma factor activity The function of binding to an anti-sigma factor and stopping, preventing or reducing the rate of its activity. UBERON:0005194 thoracic vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005194 A vein that is part of a thorax [Automatically generated definition]. GO:0043855 cyclic nucleotide-gated ion channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043855 cyclic nucleotide-activated ion channel activity|cyclic nucleotide activated ion channel activity|cyclic nucleotide gated ion channel activity Enables the transmembrane transfer of an ion by a channel that opens when a cyclic nucleotide has been bound by the channel complex or one of its constituent parts. PO:0005022 plant ovary wall biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0005022 pared del ovario (Spanish, exact)|子房壁 (Japanese, exact) A portion of plant tissue (PO:0009007) that is composed of plant ovary outer epidermis (PO:0005023), plant ovary inner epidermis (PO:0005024), and a plant ovary wall middle layer (PO:0005025) CHEBI:68472 pyrimidine deoxyribonucleoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68472 CHEBI:68471 (Z)-2,3-dehydroadipoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68471 UBERON:0005181 thoracic segment organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005181 upper body organ An organ that part of the thoracic segment region. This region can be further subdividied chest and thoracic cavity regions. GO:0043861 agmatine:putrescine antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043861 agmatine/putrescine antiporter activity|agmatine-putrescine antiporter activity Catalysis of the reaction: agmatine(out) + putrescine(in) = agmatine(in) + putrescine(out). GO:0043860 cyanophycin synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043860 EC:6.3.1.- cphA Catalysis of the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer). GO:0043863 4-hydroxy-2-ketopimelate aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043863 MetaCyc:4-HYDROXY-2-KETOPIMELATE-LYSIS-RXN|RHEA:25788 HHED aldolase activity|HpaI|HpcH|2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase activity Catalysis of the reaction: 4-hydroxy-2-ketopimelate = succinate semialdehyde + pyruvate. GO:0043862 arginine:agmatine antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043862 AdiC|arginine/agmatine antiporter activity|arginine-agmatine antiporter activity|arginine-agmatine exchange transporter activity Catalysis of the reaction: arginine(out) + agmatine(in) = arginine(in) + agmatine(out). GO:0043869 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043869 GO:0043868 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043868 GO:0043865 methionine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043865 methionine importing activity|methionine importer|methionine importer activity|methionine-importing activity Enables the transfer of methionine from one side of a membrane to the other. UBERON:0005185 renal medulla collecting duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005185 kidney medulla collecting duct|medullary collecting duct The portion of the collecting duct that resides in the renal medulla GO:0043864 indoleacetamide hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043864 MetaCyc:G-5841|RHEA:45048|EC:3.5.1.4 IaaH|Tms2|IAH|indole-3-acetamide hydrolase activity|indole acetamide hydrolase activity Catalysis of the reaction: indole-3-acetamide + H2O = indole-3-acetate + NH3. Indole-3-acetamide is known as IAM and indole-3-acetate as IAA. UBERON:0005184 hair medulla biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005184 medulla of hair shaft Innermost layer of the hair shaft. GO:0043867 7-cyano-7-deazaguanine tRNA-ribosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043867 TgtA|archaeal tRNA-guanine transglycosylase activity|archaeosine tRNA-ribosyltransferase activity Catalysis of the reaction: tRNA guanine + 7-cyano-7-deazaguanine = tRNA 7-cyano-7-deazaguanine + guanine. GO:0043866 adenylyl-sulfate reductase (thioredoxin) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043866 RHEA:21976|EC:1.8.4.10 AMP, sulfite:thioredoxin-disulfide oxidoreductase (adenosine-5'-phosphosulfate-forming)|AMP,sulfite:thioredoxin-disulfide oxidoreductase (adenosine-5'-phosphosulfate-forming)|thioredoxin-dependent 5'-adenylylsulfate reductase activity Catalysis of the reaction: AMP + sulfite + thioredoxin disulfide = 5'-adenylyl sulfate + thioredoxin. PO:0005011 anther dehiscence zone biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0005011 zona de dehiscencia de la antera (Spanish, exact)|開葯帯 (Japanese, exact) A dehiscence zone (PO:0025092) that is part of an anther (PO:0009066). PO:0005010 anther septum biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0005010 septo de la antera (Spanish, exact)|anther dissepiment (broad)|葯隔壁 (Japanese, exact) A septum (PO:0000030) that is part of an anther dehiscence zone (PO:0005011). CHEBI:68483 UDP-N-acetyl-3-O-(1-carboxylatovinyl)-alpha-D-glucosamine(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68483 CHEBI:68485 alpha-D-Galp-(1->4)-beta-D-Galp-(1->4)-beta-D-Glcp biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68485 CHEBI:68481 mTOR inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68481 GO:0043872 lysine:cadaverine antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043872 cadaverine:lysine antiporter activity|lysine/cadaverine antiporter activity|cadaverine transmembrane transporter activity|lysine-cadaverine antiporter activity Catalysis of the reaction: lysine(out) + cadaverine(in) = lysine(in) + cadaverine(out). UBERON:0005170 granulosa cell layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005170 membrana granulosa|ovary stratum granulosum|granulosa cell layer of ovarian follicle|granulosa cell layers|membrana granulosa of ovarian follicle|granulosa cell layer|stratum granulosum of ovarian follicle A layer of the ovarian follicle that consists of granulosa cells. GO:0043871 delta1-piperideine-6-carboxylate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043871 RHEA:49476|MetaCyc:RXN-8162 PIPOX|AmaB Catalysis of the reaction: delta1-piperideine-6-carboxylate + NAD+ + 2 H2O = 2-aminoadipate + NADH + H+. Delta1-piperideine-6-carboxylate is also known as 2,3,4,5-tetrahydropyridine-2-carboxylate. GO:0043874 acireductone synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043874 MetaCyc:3.1.3.77-RXN|Reactome:R-HSA-1237129|RHEA:21700|EC:3.1.3.77 E-1|5-(methylthio)-2,3-dioxopentyl-phosphate phosphohydrolase (isomerizing)|E-1 enolase-phosphatase Catalysis of the reactions: 5-(methylthio)-2,3-dioxopentyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate; (1a) 5-(methylthio)-2,3-dioxopentyl phosphate = 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate; (1b) 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate. GO:0043873 pyruvate-flavodoxin oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043873 RHEA:44140|MetaCyc:PYFLAVOXRE-RXN NifJ|pyruvate:flavodoxin oxidoreductase activity Catalysis of the reaction: pyruvate + CoA + oxidized flavodoxin = acetyl-CoA + CO2 + reduced flavodoxin. CHEBI:68487 strigolactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68487 GO:0043870 N-acetyl-gamma-aminoadipyl-phosphate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043870 RHEA:41948|MetaCyc:RXN-5183 N-acetyl-aminoadipate semialdehyde dehydrogenase activity|N-acetyl-alpha-glutamyl-phosphate reductase activity|AGPR|NAGSA dehydrogenase activity|LysY|ArgC Catalysis of the reaction: N(2)-acetyl-L-aminoadipate-semialdehyde + NADP+ + phosphate = N(2)-acetyl-L-gamma-aminoadipyl phosphate + NADPH. CHEBI:68489 alkyl,acyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68489 CHEBI:68488 alkyl,acyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68488 UBERON:0005178 thoracic cavity element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005178 thoracic cavity organ An organ or element that is in the thoracic cavity. Examples: lung, heart, longus colli. GO:0043879 glycolate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043879 glycolic acid transmembrane transporter activity|glcA|hydroxyacetic acid transmembrane transporter activity|glycolate permease Enables the transfer of glycolate from one side of a membrane to the other. Glycolate is the smallest alpha-hydroxy acid (AHA). UBERON:0005177 trunk region element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005177 trunk organ An organ or element that part of the trunk region. The trunk region can be further subdividied into thoracic (including chest and thoracic cavity) and abdominal (including abdomen and pelbis) regions. UBERON:0005176 tooth enamel organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005176 enamel organ|odontogenic organ|organum enameleum|dental organ A circumscribed mass of ectodermal cells which bud off from the dental lamina; it becomes cup-shaped and develops on its internal face the ameloblast layer of cells that produces the enamel cap of a developing tooth. UBERON:0005175 chest organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005175 An organ that is part of a chest [Automatically generated definition]. GO:0043876 D-threonine aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043876 RHEA:15257|MetaCyc:4.1.2.42-RXN|EC:4.1.2.42 D-allo-TA|DtaAS|D-TA|D-allo-threonine aldolase activity|low-specificity D-threonine aldolase Catalysis of the reaction: D-threonine (or D-allo-threonine) = glycine + acetaldehyde. UBERON:0005174 dorsal region element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005174 dorsal region organ|back organ An organ or element that part of the dorsum of the organism. Examples: spinal cord, vertebrae, muscles of back. GO:0043875 2-ketobutyrate formate-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043875 MetaCyc:KETOBUTFORMLY-RXN keto-acid formate acetyltransferase|KFL|TdcE Catalysis of the reaction: 2-oxobutanoate + coenzyme A = propionyl-CoA + formate. UBERON:0005173 abdominal segment element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005173 abdominal segment organ An organ or element that is part of the adbominal segment of the organism. This region can be further subdivided into the abdominal cavity and the pelvic region. CHEBI:19504 2-chloro-cis,cis-muconate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_19504 GO:0043878 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043878 RHEA:25294|EC:1.2.1.3|MetaCyc:RXN-3443 glyceraldehyde-3-phosphate dehydrogenase (NAD) (non-phosphorylating) activity|non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (NAD)|NAD+-dependent glyceraldehyde-3-phosphate dehydrogenase activity|glyceraldehyde-3-phosphate dehydrogenase (NAD) activity Catalysis of the reaction: D-glyceraldehyde 3-phosphate + NAD+ + H2O = 3-phospho-D-glycerate + NADH + H+. UBERON:0005172 abdomen element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005172 abdomen organ An organ or element that is in the abdomen. Examples: spleen, intestine, kidney, abdominal mammary gland. GO:0043877 galactosamine-6-phosphate isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043877 AgaI|galactosamine-6-phosphate deaminase activity Catalysis of the reaction: D-galactosamine 6-phosphate + H2O = D-tagatose 6-phosphate + NH3. CHEBI:19503 propachlor biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_19503 UBERON:0005171 hepatic duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005171 Any portion of the ducts that carry bile from the liver to the common bile duct. This may include both intrahapetic components (parts of left and right hepatic ducts) and extrahapetic components (common hepatic duct, plus hilar portion). UBERON:5101466 pedal digit digitopodial skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_5101466 pedal digit skeleton|pedal digit A subdivision of the skeleton of the autopod consisting of the phalanges of pedal digit plus the associated metapodial element. UBERON:0005179 pelvic region element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005179 pelvic element|pelvis region organ|pelvis organ An organ or element that is part of the pelvic region. Examples: reproductive organs (in some organisms), urinary bladder, bones of the pelvis. CHEBI:68494 apoptosis inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68494 CHEBI:68493 dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68493 CHEBI:68495 apoptosis inducer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68495 CHEBI:68490 alkyl,acyl-sn-glycero-3-phospho-L-serine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68490 CHEBI:68492 dTDP-4-amino-4,6-dideoxy-alpha-D-galactose(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68492 GO:0043883 malolactic enzyme activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043883 MleS Catalysis of the reaction: malate + H+ = L-lactate + CO2. GO:0043882 malate:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043882 malate-sodium symporter activity|malate Na(+) symporter activity|malate/sodium symporter activity|malate/sodium cotransporter activity|sodium/malate symporter activity|Na(+)-malate symporter activity|malate:Na+ symporter activity|malate:sodium cotransporter activity|sodium:malate symporter activity|Na+:malate symporter activity|sodium-dependent malate transporter Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: malate(out) + Na+(out) = malate(in) + Na+(in). GO:0043885 carbon-monoxide dehydrogenase (ferredoxin) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043885 EC:1.2.7.4|MetaCyc:CARBON-MONOXIDE-DEHYDROGENASE-RXN carbon-monoxide:(acceptor) oxidoreductase activity|carbon monoxide dehydrogenase (ferredoxin) activity|CO dehydrogenase activity|CODH|CO-dehydrogenase (ferredoxin) activity|carbon monoxide dehydrogenase activity|carbon-monoxide dehydrogenase activity|carbon-monoxide,water:ferredoxin oxidoreductase activity|CO-dehydrogenase activity Catalysis of the reaction: CO + H2O + oxidized ferredoxin = CO2 + reduced ferredoxin. GO:0043884 CO-methylating acetyl-CoA synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043884 MetaCyc:ACETYLSYNCLTH-RXN|RHEA:45212|EC:2.3.1.169 CO-methylating acetyl-coenzyme A synthase activity|acetyl-CoA:corrinoid protein O-acetyltransferase activity|ACS|acetyl-CoA synthase activity Catalysis of the reaction: acetyl-CoA + corrinoid protein = CO + methylcorrinoid protein + CoA. CHEBI:68498 lysophosphatidyl-1D-myo-inositol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68498 CHEBI:68497 lysophosphatidylserine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68497 GO:0043881 mesaconyl-CoA hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043881 mch|mesaconyl-coenzyme A hydratase activity|beta-methylmalyl-CoA dehydratase activity Catalysis of the hydration of mesaconyl-CoA to beta-methylmalyl-CoA. GO:0043880 crotonyl-CoA reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043880 CCR|crotonyl-coenzyme A reductase activity Catalysis of the reduction of crotonyl-CoA to butyryl-CoA. NCBITaxon:55879 Rhabditoidea organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_55879 UBERON:0005164 ascending limb of loop of Henle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005164 distal straight tubule|loop of Henle ascending limb|ascending limb of Henle's loop|ascending limb The distal part of the loop of Henle that is impermeable to water and actively pumps sodium out of the filtrate to generate the hypertonic interstitium that drives countercurrent exchange; it consists of an initial very thin segment lined by simple squamous epithelium followed by a distal thick segment lined by simple cuboidal epithelium[MP]. GO:0043887 melibiose:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043887 Na+:melibiose symporter activity|melibiose:Na+ symporter activity|melibiose/sodium symporter activity|sodium:melibiose symporter activity|melibiose permease|melibiose/Na+ symporter activity|Na+/melibiose symporter activity|sodium/melibiose symporter activity|melibiose-Na+ symporter activity|thiomethylgalactoside permease II|Na+-melibiose symporter activity|sodium-melibiose symporter activity|Na+ (Li+)/melibiose symporter activity|MelB|melibiose carrier protein|melibiose-sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: melibiose(out) + Na+(out) = melibiose(in) + Na+(in). UBERON:0005162 multi cell part structure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005162 cell part cluster|multi-cell-part structure|multi-cell-component structure A structure consisting of multiple cell components but which is not itself a cell and does not have (complete) cells as a part. GO:0043886 structural constituent of carboxysome biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043886 The action of a molecule that contributes to the structural integrity of a carboxysome, an organelle found in all cyanobacteria and some chemoautotrophs, consisting of a proteinaceous coat and enzymes for the fixation of CO(2). GO:0043889 (S)-3-O-geranylgeranylglyceryl phosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043889 (S)-GGGP synthase activity|GGGPS|GGGP synthase activity|(S)-3-O-geranylgeranylglycerylphosphate synthase activity Catalysis of the alkylation of the primary hydroxyl group in (S)-glyceryl phosphate by geranylgeranyl diphosphate to form (S)-3-O-geranylgeranylglyceryl phosphate. GO:0043888 (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043888 EC:2.5.1.- DGGGPS|DGGGP synthase activity|UbiA|2,3-dGGGPS Catalysis of the transfer of a geranylgeranyl group from geranylgeranyl diphosphate to (S)-3-O-geranylgeranylglyceryl phosphate to form (S)-2,3-di-O-geranylgeranylglyceryl phosphate. UBERON:0005169 interstitial tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005169 interstitium connective tissue between the cellular elements of a structure. GO:0102551 homogentisate geranylgeranyl transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102551 EC:2.5.1.116|RHEA:38003|MetaCyc:RXN-14929 Catalysis of the reaction: 2-trans,6-trans,10-trans-geranylgeranyl diphosphate + homogentisate + H+ <=> diphosphoric acid + 2-methyl-6-geranylgeranyl-1,4-benzoquinol + carbon dioxide. GO:0102550 2-methyl-6-geranylgeranyl-1,4-benzoquinol methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102550 EC:2.1.1.295|RHEA:38007|MetaCyc:RXN-14917 Catalysis of the reaction: S-adenosyl-L-methionine + 2-methyl-6-geranylgeranyl-1,4-benzoquinol <=> S-adenosyl-L-homocysteine + 2,3-dimethyl-6-geranylgeranyl-1,4-benzoquinol + H+. GO:0102553 lipoyl synthase activity (acting on pyruvate dehydrogenase E2 protein) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102553 MetaCyc:RXN-14957|EC:2.8.1.8 Catalysis of the reaction: 2 S-adenosyl-L-methionine + a [pyruvate dehydrogenase E2 protein] N6-octanoyl-L-lysine + 2 a sulfurated [sulfur carrier] = 2 L-methionine + 2 5'-deoxyadenosine + 2 H+ + a [pyruvate dehydrogenase E2 protein] N6-lipoyl-L-lysine + 2 an unsulfurated [sulfur carrier]. GO:0043894 acetyl-CoA synthetase acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043894 Pat|Pat enzyme|protein acetyltransferase activity Catalysis of the acetylation of residue Lys609 of the enzyme acetyl-CoA synthetase, using acetyl-CoA as substrate. GO:0102552 lipoyl synthase activity (acting on glycine-cleavage complex H protein biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102552 MetaCyc:RXN-14950|EC:2.8.1.8 Catalysis of the reaction: 2 S-adenosyl-L-methionine + a [glycine-cleavage complex H protein] N6-octanoyl-L-lysine + 2 a sulfurated [sulfur carrier] = 2 L-methionine + 2 5'-deoxyadenosine + a [glycine-cleavage complex H protein] N6-lipoyl-L-lysine + 2 an unsulfurated [sulfur carrier]. GO:0043893 acetate:cation symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043893 cation:acetate symporter activity|acetate-cation symporter activity|acetate/cation symporter activity|ActP|cation/acetate symporter activity|cation-acetate symporter activity|acetate permease Enables the transfer of acetate from one side of a membrane to the other according to the reaction: acetate(out) + cation(out) = acetate(in) + cation(in). GO:0043896 glucan 1,6-alpha-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043896 MetaCyc:3.2.1.70-RXN|EC:3.2.1.70 exo-1,6-alpha-glucosidase activity|exo-1,6-beta-glucosidase|glucan-1,6-alpha-glucosidase activity|glucan alpha-1,6-D-glucohydrolase activity|glucodextrinase|glucodextranase activity Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in (1->6)-alpha-D-glucans and derived oligosaccharides. GO:0102555 octanoyl transferase activity (acting on glycine-cleavage complex H protein) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102555 MetaCyc:RXN-14966|EC:2.3.1.181|RHEA:17665 Catalysis of the reaction: [glycine cleavage system lipoyl-carrier protein]-L-lysine + octanoyl-ACP = H+ + a [glycine-cleavage complex H protein] N6-octanoyl-L-lysine + a holo-[acyl-carrier protein]. GO:0102554 lipoyl synthase activity (acting on 2-oxoglutarate-dehydrogenase E2 protein biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102554 MetaCyc:RXN-14959 Catalysis of the reaction: 2 S-adenosyl-L-methionine + a [2-oxoglutarate-dehydrogenase E2 protein] N6-octanoyl-L-lysine + 2 a sulfurated [sulfur carrier] = 2 L-methionine + 2 5'-deoxyadenosine + 2 H+ + a [2-oxoglutarate dehydrogenase E2 protein] N6-lipoyl-L-lysine + 2 an unsulfurated [sulfur carrier]. GO:0043895 cyclomaltodextrin glucanotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043895 EC:2.4.1.19|MetaCyc:2.4.1.19-RXN cyclodextrin glucanotransferase|beta-cyclodextrin glycosyltransferase|1,4-alpha-D-glucan 4-alpha-D-(1,4-alpha-D-glucano)-transferase (cyclizing)|CGTase|alpha-cyclodextrin glucanotransferase|alpha-cyclodextrin glycosyltransferase|Bacillus macerans amylase|cyclomaltodextrin glycosyltransferase|BMA|cyclomaltodextrin glucotransferase|alpha-1,4-glucan 4-glycosyltransferase, cyclizing|gamma-cyclodextrin glycosyltransferase|beta-cyclodextrin glucanotransferase|neutral-cyclodextrin glycosyltransferase|konchizaimu|cyclodextrin glycosyltransferase Catalysis of the cyclization of part of a 1,4-alpha-D-glucan chain by formation of a 1,4-alpha-D-glucosidic bond. GO:0043890 N-acetylgalactosamine-6-sulfatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043890 Reactome:R-HSA-1630304|MetaCyc:3.1.6.4-RXN|Reactome:R-HSA-2263490|EC:3.1.6.4 N-acetyl-D-galactosamine-6-sulfate 6-sulfohydrolase activity|chondroitinase|galactose-6-sulfate sulfatase activity|acetylgalactosamine 6-sulfatase activity|chondroitinsulfatase|N-acetylgalactosamine 6-sulfatase activity|N-acetylgalactosamine-6-sulfate sulfatase activity|chondroitin sulfatase Catalysis of the hydrolysis of the 6-sulfate groups of the N-acetyl-D-galactosamine 6-sulfate units of chondroitin sulfate and of the D-galactose 6-sulfate units of keratan sulfate. GO:0102557 protopanaxadiol 6-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102557 RHEA:22272|MetaCyc:RXN-14978|EC:1.14.14.121 Catalysis of the reaction: (20S)-protopanaxadiol + O2 + NADPH(4-) + H+ <=> protopanaxatriol + NADP + H2O. GO:0102556 dammarenediol 12-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102556 MetaCyc:RXN-14975|EC:1.14.14.120|RHEA:38579 Catalysis of the reaction: dammarenediol-II + NADPH + H+ + O2 <=> (20S)-protopanaxadiol + NADP + H2O. GO:0043892 methylglyoxal reductase (NADPH-dependent) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043892 MetaCyc:1.1.1.283-RXN|EC:1.1.1.283|MetaCyc:RXN-8636|RHEA:21748 lactaldehyde dehydrogenase (NADP+)|Gre2|lactaldehyde:NADP+ oxidoreductase activity Catalysis of the reaction: lactaldehyde + NADP+ = methylglyoxal + NADPH + H+. GO:0102559 protein-(glutamine-N5) methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102559 EC:2.1.1.297|MetaCyc:RXN-14992|RHEA:42896 Catalysis of the reaction: S-adenosyl-L-methionine + a [release factor]-L-glutamine = S-adenosyl-L-homocysteine + H+ + a [release factor]-N5-methyl-L-glutamine. GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043891 MetaCyc:GAPDHSYNEC-RXN|EC:1.2.1.59 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) (phosphorylating)|D-glyceraldehyde 3-phosphate:NAD(P)+ oxidoreductase (phosphorylating)|triosephosphate dehydrogenase (NAD(P))|triosephosphate dehydrogenase (NAD(P)+)|NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase activity Catalysis of the reaction: D-glyceraldehyde 3-phosphate + phosphate + NAD(P)+ = 3-phospho-D-glyceroyl phosphate + NAD(P)H + H+. OBO:GOCHE_35703 substance with xenobiotic role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_35703 GO:0043898 2,3-dihydroxybiphenyl 1,2-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043898 BphC|2,3-dihydroxybiphenyl-1,2-dioxygenase activity Catalysis of the reaction: 2,3-dihydroxybiphenyl + O2 = 2-hydroxy-6-phenylhexa-2,4-dienoic acid. GO:0043897 glucan 1,4-alpha-maltohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043897 EC:3.2.1.133|MetaCyc:3.2.1.133-RXN glucan-1,4-alpha-maltohydrolase activity|maltogenic alpha-amylase activity|1,4-alpha-D-glucan alpha-maltohydrolase activity Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides so as to remove successive alpha-maltose residues from the non-reducing ends of the chains. GO:0043899 phosphoserine:homoserine phosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043899 thrH Catalysis of the transfer of a phosphoryl group from phosphoserine to homoserine to form phosphohomoserine. GO:0102560 5-phospho-alpha-D-ribose 1,2-cyclic phosphate 1-phosphohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102560 RHEA:41612|EC:3.1.4.57|MetaCyc:RXN-14995 phosphoribosyl 1,2-cyclic phosphate 1,2-diphosphodiesterase Catalysis of the reaction: 5-phosphonato-alpha-D-ribose cyclic-1,2-phosphate + H2O <=> D-ribofuranose 2,5-bisphosphate + H+. GO:0102562 hydroxyproline O-arbinofuranose transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102562 RHEA:49472|MetaCyc:RXN-15011 Catalysis of the reaction: UDP-beta-L-arabinofuranose + a [protein]-trans-4-hydroxy-L-proline = UDP + H+ + a protein-O-(beta-L-arabinofuranose)-trans-4-hydroxy-L-proline. GO:0102561 D-ribose 2,5-bisphosphate 2-phosphohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102561 EC:3.1.4.57|MetaCyc:RXN-14996|RHEA:41617 Catalysis of the reaction: H2O + D-ribofuranose 2,5-bisphosphate <=> hydrogenphosphate + D-ribofuranose 5-phosphate. GO:0102564 aurachin C epoxide hydrolase/isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102564 MetaCyc:RXN-15030|RHEA:48728 Catalysis of the reaction: aurachin C epoxide + H+ + NAD(P)H <=> aurachin B + H2O + NAD(P). GO:0102563 aurachin C monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102563 MetaCyc:RXN-15029 Catalysis of the reaction: aurachin C + O2 + H+ + NAD(P)H <=> aurachin C epoxide + H2O + NAD(P). GO:0102566 1-acyl dihydroxyacetone phosphate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102566 EC:1.1.1.101|MetaCyc:RXN-15046 Catalysis of the reaction: 1-oleoylglycerone 3-phosphate + NADPH + H+ = 1-oleoyl-sn-glycero-3-phosphate + NADP. GO:0102568 phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102568 MetaCyc:RXN-15067|EC:3.1.1.4 Catalysis of the reaction: 1-18:1-2-18:1-phosphatidylethanolamine + H2O = 1-oleoyl-sn-glycero-3-phosphoethanolamine + oleate + H+. GO:0102567 phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102567 MetaCyc:RXN-15065|EC:3.1.1.4 Catalysis of the reaction: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + hexadecanoate + H+. GO:0102569 FR-33289 synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102569 MetaCyc:RXN-15082 Catalysis of the reaction: FR-900098 + 2-oxoglutarate(2-) + O2 <=> FR-33289 + succinate(2-) + carbon dioxide. OBO:GOCHE_35718 substance with antifungal agent role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_35718 GO:0102571 [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102571 MetaCyc:RXN-15215|EC:3.2.1.169 Catalysis of the reaction: H2O + an N-acetyl-alpha-D-glucosaminyl-[glycoprotein] <=> N-acetyl-alpha-D-glucosaminide + a [glycoprotein]-(L-serine/L-threonine). GO:0102570 tyrosine:phenylpyruvate aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102570 MetaCyc:RXN-15200 Catalysis of the reaction: keto-phenylpyruvate + L-tyrosine = L-phenylalanine + 3-(4-hydroxyphenyl)pyruvate. GO:0102573 aminodeoxyfutalosine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102573 EC:2.5.1.120|MetaCyc:RXN-15264|RHEA:33075 Catalysis of the reaction: 3-[(1-carboxylatovinyl)oxy]benzoate(2-) + S-adenosyl-L-methionine + H2O <=> aminodeoxyfutalosinate + L-methionine + hydrogencarbonate + H+. GO:0102572 N-glutamylanilide hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102572 MetaCyc:RXN-15251|RHEA:50684 Catalysis of the reaction: N5-phenyl-L-glutamine + H2O = L-glutamate + aniline + H+. GO:0102575 3-oxo-dodecanoyl-ACP hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102575 MetaCyc:RXN-15281 Catalysis of the reaction: H2O + a 3-oxo-dodecanoyl-[acp] = 3-oxododecanoate + H+ + a holo-[acyl-carrier protein]. GO:0102574 3-oxo-myristoyl-ACP hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102574 MetaCyc:RXN-15280 Catalysis of the reaction: H2O + a 3-oxo-myristoyl-[acp] = 3-oxo-myristate + H+ + a holo-[acyl-carrier protein]. GO:0102577 3-oxo-palmitate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102577 MetaCyc:RXN-15283|EC:4.1.1.56 Catalysis of the reaction: 3-oxopalmitic acid + H+ = 2-pentadecanone + carbon dioxide. GO:0102576 3-oxo-palmitoyl-ACP hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102576 MetaCyc:RXN-15282 Catalysis of the reaction: H2O + a 3-oxo-palmitoyl-[acp] = 3-oxopalmitic acid + H+ + a holo-[acyl-carrier protein]. PO:0005029 root primordium biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0005029 primordio de raíz (Spanish, exact)|根原基（可視的） (Japanese, exact)|root primordia (exact, plural)|portion of root primordium tissue (exact) A primordium (PO:0025127) that develops from a root anlagen (PO:0025433) and is committed to the development of a root (PO:0009005). GO:0102580 cyanidin 3-O-glucoside 2-O''-xylosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102580 EC:2.4.2.51|RHEA:35443|MetaCyc:RXN-15326 Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + UDP-alpha-D-xylose <=> cyanidin 3-O-beta-D-sambubioside + UDP. GO:0102582 cyanidin 3-O-p-coumaroylglucoside 2-O''-xylosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102582 MetaCyc:RXN-15328 Catalysis of the reaction: cyanidin 3-O-(6-O-(E)-4-coumaroyl-beta-D-glucoside) + UDP-alpha-D-xylose <=> cyanidin 3-O-[2''-O-xylosyl) 6''-O-(p-coumaroyl) glucoside + UDP + H+. GO:0102581 cyanidin 3-O-glucoside-p-coumaroyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102581 MetaCyc:RXN-15327 Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 4-coumaryl-CoA + H+ <=> cyanidin 3-O-(6-O-(E)-4-coumaroyl-beta-D-glucoside) + coenzyme A. GO:0102584 cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102584 MetaCyc:RXN-15330 Catalysis of the reaction: cyanidin 3-O-[2''-O-xylosyl) 6''-O-(p-coumaroyl) glucoside + UDP-alpha-D-glucose <=> cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-glucoside + UDP + H+. GO:0102583 cyanidin 3-O-glucoside-(2''-O-xyloside) 6''-O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102583 MetaCyc:RXN-15329 Catalysis of the reaction: cyanidin 3-O-beta-D-sambubioside + 4-coumaryl-CoA <=> cyanidin 3-O-[2''-O-xylosyl) 6''-O-(p-coumaroyl) glucoside + coenzyme A. GO:0102586 cyanidin 3-O-[2''-O-(2''-O-(sinapoyl) xylosyl) 6''-O-(p-coumaroyl) glucoside] 5-O-[6''-O-(malonyl) glucoside] sinapoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102586 MetaCyc:RXN-15332 Catalysis of the reaction: cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-malonylglucoside + 1-O-sinapoyl-beta-D-glucose <=> cyanidin 3-O-[2''-O-(2''-O-(sinapoyl) xylosyl) 6'-O-(p-coumaroyl) glucoside] 5-O-[6''-O-(malonyl) glucoside + beta-D-glucose. GO:0102585 cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-glucoside malonyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102585 MetaCyc:RXN-15331 Catalysis of the reaction: cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-glucoside + malonyl-CoA + H+ <=> cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-malonylglucoside + coenzyme A. GO:0102588 cyanidin 3-O-glucoside 6''-O-malonyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102588 EC:2.3.1.171|MetaCyc:RXN-15335 Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + malonyl-CoA <=> cyanidin 3-O-(6-O-malonyl-beta-D-glucoside) + coenzyme A. GO:0102587 cyanidin 3-O-[2''-O-(2''-O-(sinapoyl) xylosyl) 6''-O-(p-O-(glucosyl)-p-coumaroyl) glucoside] 5-O-[6''-O-(malonyl) glucoside] sinapoylglucose glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102587 MetaCyc:RXN-15333 Catalysis of the reaction: cyanidin 3-O-[2''-O-(2'''-O-(sinapoyl) xylosyl) 6''-O-(p-coumaroyl) glucoside] 5-O-[6''-O-(malonyl) glucoside + 1-O-sinapoyl-beta-D-glucose <=> cyanidin 3-O-[6-O-(4-O-beta-D-glucosyl-p-coumaroyl)-2-O-(2-O-sinapoyl-beta-D-xylosyl)-beta-D-glucosyl]-5-O-(6-O-malonyl-beta-D-glucoside) + trans-sinapate + H+. GO:0102589 cyanidin 3-O-glucoside 3'',6''-O-dimalonyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0102589 MetaCyc:RXN-15336 Catalysis of the reaction: cyanidin 3-O-(6-O-malonyl-beta-D-glucoside) + malonyl-CoA(5-) <=> cyanidin 3-O-(3''', 6''-O-dimalonyl-beta-glucopyranoside) + coenzyme A. CHEBI:20441 4-(methylamino)butyrate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20441 GO:0018807 6-hydroxycyclohex-1-ene-1-carboxyl-CoA hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018807 UM-BBD_reactionID:r0204|EC:3.7.1.21|RHEA:39651 Catalysis of the reaction: 6-hydroxycyclohex-1-ene-1-carboxyl-CoA + H2O = 2,6-dihydroxycyclohexane-1-carboxyl-CoA. GO:0018806 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018806 GO:0018809 E-phenylitaconyl-CoA hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018809 UM-BBD_reactionID:r0331 Catalysis of the reaction: E-phenylitaconyl-CoA + H2O = (hydroxymethylphenyl)succinyl-CoA. GO:0018808 trans-4-(1'-hydroxynaphth-2'-yl)-2-oxobut-3-enoate hydratase-aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018808 UM-BBD_reactionID:r0484 Catalysis of the reaction: trans-4-(1'-hydroxynaphth-2'-yl)-2-oxobut-3-enoate + H2O = pyruvate + 1-hydroxy-2-naphthaldehyde. GO:0018803 4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018803 EC:4.1.2.34|UM-BBD_reactionID:r0487|RHEA:16453|MetaCyc:4.1.2.34-RXN (3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-carboxybenzaldehyde-lyase (pyruvate-forming)|2'-carboxybenzalpyruvate aldolase activity|(3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-carboxybenzaldehyde-lyase activity|trans-2'-carboxybenzalpyruvate hydratase-aldolase activity|(3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-carboxybenzaldehyde-lyase activity Catalysis of the reaction: (3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate = 2-carboxybenzaldehyde + pyruvate. UBERON:0005233 medial-nasal process ectoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005233 An ectoderm that is part of a medial nasal prominence [Automatically generated definition]. GO:0018802 2,4-dihydroxyhept-2-ene-1,7-dioate aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018802 EC:4.1.2.-|UM-BBD_reactionID:r0370 Catalysis of the reaction: 2,4-dihydroxy-hept-trans-2-ene-1,7-dioate = pyruvate + succinic semialdehyde. GO:0018805 benzylsuccinate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018805 MetaCyc:RXN-863|UM-BBD_enzymeID:e0259|EC:4.1.99.11|RHEA:10416|KEGG_REACTION:R05598 benzylsuccinate fumarate-lyase activity|benzylsuccinate fumarate-lyase (toluene-forming) Catalysis of the reaction: fumarate + toluene = 2-benzylsuccinate. GO:0018804 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018804 GO:0018801 glutaconyl-CoA decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018801 UM-BBD_reactionID:r0199|KEGG_REACTION:R03028|EC:7.2.4.5|RHEA:23972|MetaCyc:GLUTACONYL-COA-DECARBOXYLASE-RXN glutaconyl coenzyme A decarboxylase activity|4-carboxybut-2-enoyl-CoA carboxy-lyase (but-2-enoyl-CoA-forming)|4-carboxybut-2-enoyl-CoA carboxy-lyase activity|pent-2-enoyl-CoA carboxy-lyase activity Catalysis of the reaction: trans-glutaconyl-CoA + H(+) = but-2-enoyl-CoA + CO(2). GO:0018800 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018800 EC:4.1.1.68|UM-BBD_reactionID:r0367|RHEA:14397|MetaCyc:4.1.1.68-RXN HpaG2|OPET decarboxylase activity|5-oxopent-3-ene-1,2,5-tricarboxylate carboxy-lyase activity|HpaG-2|5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase activity|5-oxopent-3-ene-1,2,5-tricarboxylate carboxy-lyase (2-oxohept-3-enedioate-forming)|5-carboxymethyl-2-oxo-hex-3-ene-1,6-dioate decarboxylase activity Catalysis of the reaction: 5-oxopent-3-ene-1,2,5-tricarboxylate = 2-oxohept-3-enedioate + CO2. CHEBI:19448 2-amino-3-(3-oxoprop-1-enyl)but-2-enedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19448 UBERON:0005239 basal plate metencephalon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005239 metencephalon basal plate UBERON:0005234 optic eminence ectoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005234 An ectoderm that is part of a optic eminence [Automatically generated definition]. CHEBI:44400 2-iminiopropionate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_44400 GO:0018818 acetylene hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018818 UM-BBD_reactionID:r0591|MetaCyc:R141-RXN|RHEA:17885|EC:4.2.1.112|KEGG_REACTION:R05380 AH|acetaldehyde hydro-lyase activity|AHy Catalysis of the reaction: acetaldehyde = acetylene + H(2)O. GO:0018817 2-oxo-hept-3-ene-1,7-dioate hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018817 RHEA:42072|UM-BBD_reactionID:r0369|MetaCyc:HYDROXYHEPTA-DIENEDIOATE-HYDROXY-RXN 2-oxo-hepta-3-ene-1,7-dioic acid hydratase activity|HpaH|2-oxo-hepta-3-ene-1,7-dioate hydratase activity Catalysis of the reaction: cis-2-oxohept-3-ene-1,7-dioate + H2O = 2,4-dihydroxy-hept-trans-2-ene-1,7-dioate. GO:0018819 lactoyl-CoA dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018819 EC:4.2.1.54|UM-BBD_reactionID:r0086|RHEA:21056|MetaCyc:LACTOYL-COA-DEHYDRATASE-RXN|MetaCyc:RXN-781 lactoyl-CoA hydro-lyase activity|lactyl CoA dehydratase activity|lactoyl coenzyme A dehydratase activity|lactoyl-CoA hydro-lyase (acryloyl-CoA-forming)|lactyl-coenzyme A dehydrase activity|acrylyl coenzyme A hydratase activity Catalysis of the reaction: lactoyl-CoA = acryloyl-CoA + H2O. GO:0018814 phenylacetaldoxime dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018814 KEGG_REACTION:R07638|RHEA:20069|EC:4.99.1.7|MetaCyc:4.99.1.7-RXN|UM-BBD_reactionID:r0697 (Z)-phenylacetaldehyde-oxime hydro-lyase activity|arylacetaldoxime dehydratase activity|PAOx dehydratase activity|(Z)-phenylacetaldehyde-oxime hydro-lyase (phenylacetonitrile-forming) activity|OxdB Catalysis of the reaction: (trans)-phenylacetaldoxime = H(2)O + phenylacetonitrile. UBERON:0005222 liver left lobe parenchyma biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005222 parenchyma of left lobe of liver A parenchyma that is part of a left lobe of liver [Automatically generated definition]. GO:0018813 trans-o-hydroxybenzylidenepyruvate hydratase-aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018813 RHEA:27389|UM-BBD_enzymeID:e0257|EC:4.1.2.45 Catalysis of the reaction: 2-oxo-3-enoate-4-benzenoid + H2O = pyruvate + benzaldehyde derivative. Substrates are (3E)-4-(5-amino-2-hydroxy-phenyl)-2-oxo-but-3-ene-1-oic-acid (forms 5-aminosalicylaldehyde) and trans-o-hydroxybenzylidenepyruvate (forms salicylaldehyde). UBERON:0005221 liver right lobe parenchyma biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005221 parenchyma of right lobe of liver A parenchyma that is part of a right lobe of liver [Automatically generated definition]. CHEBI:44409 NADP zwitterion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_44409 GO:0018816 2-hydroxyisobutyrate dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018816 UM-BBD_reactionID:r0618 Catalysis of the reaction: 2-hydroxyisobutyrate = H2O + methacrylate. GO:0018815 3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon hydratase-aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018815 UM-BBD_reactionID:r0051|MetaCyc:RXN-645 Catalysis of the reaction: 3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon + H2O = 2-oxobut-3-enanoate + 2,5,6-trihydroxy-3-methylpyridine. GO:0018810 trans-4-[2-(3-hydroxy)-thionaphthenyl]-2-oxo-3-butenoate hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018810 UM-BBD_reactionID:r0164 Catalysis of the reaction: trans-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate + H2O = pyruvate + 3-hydroxy-2-formylbenzothiophene. GO:0018812 3-hydroxyacyl-CoA dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018812 Reactome:R-HSA-8957389 Catalysis of the reaction: alkene-CoA + H2O = alcohol-CoA. Substrates are crotonoyl-CoA (producing 3-hydroxyacyl-CoA) and 2,3-didehydro-pimeloyl-CoA (producing 3-hydroxypimeloyl-CoA). GO:0018811 cyclohex-1-ene-1-carboxyl-CoA hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018811 MetaCyc:R266-RXN|UM-BBD_reactionID:r0191 Catalysis of the reaction: cyclohex-1-ene-1-carboxyl-CoA + H2O = 2-hydroxycyclohexane-1-carboxyl-CoA. UBERON:0005229 lower leg epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005229 An epithelium that is part of a lower leg [Automatically generated definition]. UBERON:0005228 upper arm epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005228 An epithelium that is part of a forelimb stylopod [Automatically generated definition]. UBERON:0005227 manual digit epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005227 fore limb digit epithelium|finger epithelium|hand digit epithelium An epithelium that is part of a finger [Automatically generated definition]. UBERON:0005226 pedal digit epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005226 hind limb digit epithelium|toe epithelium|foot digit epithelium An epithelium that is part of a toe [Automatically generated definition]. CHEBI:19432 2-acetamidofluorenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19432 UBERON:0005225 upper leg epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005225 An epithelium that is part of a hindlimb stylopod [Automatically generated definition]. CHEBI:19471 2-aminohexano-6-lactam biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19471 UBERON:0005211 renal medulla interstitium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005211 renal medullary interstitium|medullary stroma|kidney medulla interstitium|medullary interstitium|renal medullary interstitial tissue tissue surrounding the loop of Henle in the renal medulla. UBERON:0005219 hindbrain subarachnoid space biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005219 subarachnoid space hindbrain|subarachnoid space rhombencephalon A subarachnoid space that is part of a hindbrain [Automatically generated definition]. UBERON:0005218 diencephalon subarachnoid space biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005218 subarachnoid space diencephalon A subarachnoid space that is part of a diencephalon [Automatically generated definition]. UBERON:0005217 midbrain subarachnoid space biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005217 subarachnoid space midbrain|subarachnoid space mesencephalon A subarachnoid space that is part of a midbrain [Automatically generated definition]. UBERON:0005216 optic eminence surface ectoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005216 An external ectoderm that is part of a optic eminence [Automatically generated definition]. UBERON:0005215 kidney interstitium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005215 renal interstitium|renal stroma|renal interstitial tissue|interstitial tissue of kidney|kidney interstitium group|stroma of kidney The interstitial compartment of the kidney, comprising the extravascular intertubular spaces of the renal parenchyma, with their attendant cellular elements and extracellular substances, bounded on all sides by epithelial and vascular basement membranes. UBERON:0005214 inner renal medulla interstitium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005214 kidney inner medulla interstitium|inner medullary interstitium|papillary interstitium A portion of interstitial tissue that is part of a inner medulla of kidney [Automatically generated definition]. UBERON:0005213 outer renal medulla interstitium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005213 kidney outer medulla interstitium|outer medullary interstitium A portion of interstitial tissue that is part of a outer medulla of kidney [Automatically generated definition]. UBERON:0005212 Leydig cell region of testis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005212 interstitium of the testis|testis - interstitial|interstitium of testis|testis interstitium|testis interstitial tissue The male gonad containing two functional parts: the SEMINIFEROUS TUBULES for the production and transport of male germ cells (SPERMATOGENESIS) and the interstitial compartment containing LEYDIG CELLS that produce ANDROGENS.. CHEBI:20432 imidazolone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20432 GO:0043803 hydroxyneurosporene-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043803 EC:2.1.1.210|RHEA:30903 demethylspheroidene O-methyltransferase|1-hydroxycarotenoid O-methylase|1-hydroxycarotenoid methylase|1-HO-carotenoid methylase Catalysis of the reaction: demethylspheroidene + S-adenosyl-L-methionine = H(+) + S-adenosyl-L-homocysteine + spheroidene. UBERON:0005200 thoracic mammary gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005200 lactiferous gland|mammary gland|anterior mammary gland|breast mammary gland A lactiferous gland that is located in the thoracic region/breast. GO:0043802 hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043802 EC:6.3.5.9|RHEA:12544|MetaCyc:R341-RXN|KEGG_REACTION:R05224 hydrogenobyrinic acid a,c diamide synthase (glutamine-hydrolysing) activity|hydrogenobyrinic-acid:L-glutamine amido-ligase (AMP-forming)|CobB Catalysis of the reaction: 2 L-glutamine + 2 ATP + 2 H(2)O + hydrogenobyrinate = 2 L-glutamate + 2 ADP + 4 H(+) + hydrogenobyrinate a,c-diamide + 2 phosphate. GO:0043805 indolepyruvate ferredoxin oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043805 MetaCyc:1.2.7.8-RXN|RHEA:12645|EC:1.2.7.8 indolepyruvate oxidoreductase activity|3-(indol-3-yl)pyruvate:ferredoxin oxidoreductase (decarboxylating, CoA-indole-acetylating)|3-(indol-3-yl)pyruvate synthase (ferredoxin) activity|IOR Catalysis of the reaction: (indol-3-yl)pyruvate + CoA + oxidized ferredoxin = S-2-(indol-3-yl)acetyl-CoA + CO2 + reduced ferredoxin. GO:0043804 imidazolone hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043804 RHEA:24937 Catalysis of the reaction: N-formimidoylglycine => H2O + imidazol-4-one. GO:0043801 hexulose-6-phosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043801 MetaCyc:R10-RXN|EC:4.1.2.43|RHEA:25201 Catalysis of the reaction: D-ribulose 5-phosphate + formaldehyde = D-arabino-3-hexulose 6-phosphate. GO:0043800 hexulose-6-phosphate isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043800 MetaCyc:R12-RXN|EC:5.3.1.27|RHEA:25900 HUMPI Catalysis of the reaction: D-arabino-3-hexulose 6-phosphate = D-fructose 6-phosphate. UBERON:0005208 right atrium valve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005208 superior vena cava valve|valve of right atrium|right atrium valves A valve that is part of a right atrium [Automatically generated definition]. UBERON:0005206 choroid plexus stroma biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005206 choroid plexus stromal matrix Stromal matrix surrounding blood vessels within the choroid plexus. UBERON:0005205 lamina propria of vagina biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005205 vagina stroma GO:0043807 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043807 MetaCyc:1.2.7.7-RXN|RHEA:11712|EC:1.2.7.7 2-oxoisovalerate ferredoxin reductase activity|branched-chain ketoacid ferredoxin reductase activity|2-ketoisovalerate ferredoxin reductase activity|keto-valine-ferredoxin oxidoreductase activity|3-methyl-2-oxobutanoate:ferredoxin oxidoreductase (decarboxylating; CoA-2-methylpropanoylating)|ketoisovalerate ferredoxin reductase activity|3-methyl-2-oxobutanoate synthase (ferredoxin) activity|VOR|ketoisovalerate oxidoreductase activity|branched-chain oxo acid ferredoxin reductase activity Catalysis of the reaction: 3-methyl-2-oxobutanoate + CoA + oxidized ferredoxin = S-(2-methylpropanoyl)-CoA + CO2 + reduced ferredoxin. UBERON:0005204 larynx submucosa gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005204 laryngeal submucosa gland A gland that is part of a larynx submucosa [Automatically generated definition]. GO:0043806 keto acid formate lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043806 EC:2.3.1.-|MetaCyc:KETOBUTFORMLY-RXN keto-acid formate lyase activity|keto-acid formate acetyltransferase|keto-acid formate-lyase activity Catalysis of the reaction: 2-oxobutanoate + CoA = propionyl-CoA + formate. NCBITaxon:2704949 Trypanosomatida organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_2704949 UBERON:0005203 trachea gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005203 glandula trachealis|tracheal gland|tubular seromucous gland of trachea a tubuloacinar seromucous gland that is located principally in the submucosa of the trachea. Excretory ducts from this gland pass through the lamina propria to the tracheal lumen. GO:0043809 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043809 UBERON:0005202 distal straight tubule macula densa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005202 A macula densa that is part of an ascending limb of loop of Henle [Automatically generated definition]. GO:0043808 lyso-ornithine lipid acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043808 Catalysis of the reaction: lyso-ornithine lipid + acyl-[acyl-carrier protein] = ornithine lipid + [acyl-carrier protein]. UBERON:0005277 dorsal skin of toe biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005277 skin of dorsal part of toe|subdivision of skin of dorsal part of toe|dorsal toe skin A dorsal skin of digit that is part of a pedal digit. GO:0043814 phospholactate guanylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043814 MetaCyc:RXN-8077|EC:2.7.7.68|RHEA:30519 Catalysis of the reaction: 2-phospho-(S)-lactate + GTP = lactyl-2-diphospho-5'-guanosine + diphosphate. UBERON:0005276 dorsal skin of finger biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005276 dorsal finger skin|skin of dorsal part of finger|subdivision of skin of dorsal part of finger A dorsal skin of digit that is part of a manual digit. GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043813 Reactome:R-HSA-1676005|Reactome:R-HSA-1676174|Reactome:R-HSA-1675836|Reactome:R-HSA-1676020 phosphatidylinositol 3,5-bisphosphate 5-phosphatase activity Catalysis of the reaction: phosphatidylinositol-3,5-bisphosphate + H2O = phosphatidylinositol-3-phosphate + orthophosphate. GO:0043816 phosphoserine-tRNA(Cys) ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043816 EC:6.1.1.27|RHEA:25678 O-phosphoseryl-tRNA(Cys) synthetase activity|phosphoserine--tRNA(Cys) ligase activity|phosphoserine-tRNACys ligase activity|SepRS Catalysis of the reaction: tRNA(Cys) + O-phospho-L-serine + ATP = AMP + diphosphate + phosphoseryl-tRNA(Cys). UBERON:0005275 dorsal skin of digit biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005275 dorsal digit skin|skin of dorsal part of digit GO:0043815 phosphoribosylglycinamide formyltransferase 2 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043815 RHEA:24829|MetaCyc:GARTRANSFORMYL2-RXN formate-dependent GAR transformylase activity|GAR transformylase 2|GART 2|5'-phosphoribosylglycinamide transformylase 2 Catalysis of the reaction: formate + ATP + 5'-phospho-ribosylglycinamide = 5'-phosphoribosyl-N-formylglycinamide + ADP + diphosphate. GO:0043810 ornithine-acyl [acyl carrier protein] N-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043810 RHEA:20633|EC:2.3.2.30 L-ornithine N(alpha)-acyltransferase|ornithine-acyl[acyl carrier protein] N-acyltransferase activity Catalysis of the reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + L-ornithine = lyso-ornithine lipid + [acyl-carrier protein]. The enzyme, found in bacteria, catalyzes the first step in the biosynthesis of ornithine lipids. GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043812 phosphatidylinositol 4-phosphate phosphatase activity Catalysis of the reaction: phosphatidylinositol-4-phosphate + H2O = phosphatidylinositol + orthophosphate. UBERON:0005270 renal cortex interstitium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005270 renal cortical interstitial tissue|cortical stroma|kidney cortex interstitium A compartment of the renal cortex situated between basement membranes of epithelia and vessels that contains two contiguous cellular networks in mutual contact, one formed by interstitial fibroblasts, the other by dendritic cells. GO:0043811 phosphate:acyl-[acyl carrier protein] acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043811 Catalysis of the reaction: acyl-[acyl-carrier protein] + orthophosphate = acyl phosphate + [acyl-carrier protein]. GO:0043818 precorrin-3B synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043818 KEGG_REACTION:R05217|MetaCyc:R321-RXN|RHEA:17293|EC:1.14.13.83 precorrin-3X synthase activity|CobG|precorrin-3A,NADH:oxygen oxidoreductase (20-hydroxylating) Catalysis of the reaction: H(+) + NADH + O(2) + precorrin-3A = H(2)O + NAD(+) + precorrin-3B. GO:0043817 phosphosulfolactate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043817 MetaCyc:R228-RXN|RHEA:22784|KEGG_REACTION:R07476|MetaCyc:4.4.1.19-RXN|EC:4.4.1.19 (2R)-O-phospho-3-sulfolactate sulfo-lyase activity|(2R)-O-phospho-3-sulfolactate sulfo-lyase (phosphoenolpyruvate-forming)|(2R)-phospho-3-sulfolactate synthase activity|PSL synthase activity Catalysis of the reaction: (2R)-O-phospho-3-sulfolactate = phosphoenolpyruvate + sulfite. GO:0043819 precorrin-6A synthase (deacetylating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043819 KEGG_REACTION:R05219|MetaCyc:R322-RXN|RHEA:18261|EC:2.1.1.152 CobF|precorrin-6X synthase (deacetylating) activity|S-adenosyl-L-methionine:precorrin-5 C1-methyltransferase (deacetylating) Catalysis of the reaction: S-adenosyl-L-methionine + H(2)O + precorrin-5 = S-adenosyl-L-homocysteine + acetate + 2 H(+) + precorrin-6X. NCBITaxon:55885 Peloderinae organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_55885 CHEBI:68438 Fe-coproporphyrin III(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68438 CHEBI:68437 5,6,7,8-tetrahydrofolate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68437 GO:0043825 succinylornithine transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043825 MetaCyc:SUCCORNTRANSAM-RXN|KEGG_REACTION:R04217|RHEA:16953|EC:2.6.1.81 succinyl ornithine transaminase activity|AstC|succinylornithine aminotransferase activity|N2-succinylornithine 5-aminotransferase activity|succinyl-ornithine transaminase activity|N2-succinyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity|2-N-succinyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity|N(2)-succinylornithine 5-aminotransferase activity|SOAT Catalysis of the reaction: 2-oxoglutarate + N(2)-succinyl-L-ornithine = N-succinyl-L-glutamate 5-semialdehyde + L-glutamate. GO:0043824 succinylglutamate-semialdehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043824 RHEA:10812|MetaCyc:SUCCGLUALDDEHYD-RXN|EC:1.2.1.71|KEGG_REACTION:R05049 SGSD|succinyl glutamate-semialdehyde dehydrogenase activity|AstD|AruD|N-succinyl-L-glutamate 5-semialdehyde:NAD+ oxidoreductase activity|succinylglutamic semialdehyde dehydrogenase activity|N-succinylglutamate 5-semialdehyde dehydrogenase activity Catalysis of the reaction: N-succinyl-L-glutamate 5-semialdehyde + H(2)O + NAD(+) = N-succinyl-L-glutamate + 2 H(+) + NADH. GO:0043827 tRNA (adenine-57, 58-N(1)-) methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043827 TrmI|tRNA (adenine-57, 58 N1-) methyltransferase activity|tRNA (m1A) MTase|tRNA (adenine-57, 58-N1-) methyltransferase activity Catalysis of the methylation of adenine-57 and adenine-58 in the T-loop of tRNA. GO:0043826 sulfur oxygenase reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043826 MetaCyc:RXN-8226 sulphur oxygenase reductase activity|SOR Catalysis of the reaction: 5 sulfur + oxygen + 4 H2O = sulfite + thiosulfate + 2 hydrogen sulfide + 9 H+. UBERON:0005263 outflow tract cardiac jelly biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005263 A cardiac jelly that is part of a outflow tract [Automatically generated definition]. GO:0043821 propionyl-CoA:succinate CoA-transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043821 RHEA:28010|MetaCyc:RXN0-268 propionyl-CoA:succinate CoA transferase activity|propionyl-CoA succinate CoA-transferase activity Catalysis of the reaction: succinate + propionyl-CoA = succinyl-CoA + propionate. UBERON:0005262 ventricle cardiac jelly biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005262 A cardiac jelly that is part of a ventricle [Automatically generated definition]. UBERON:0005261 atrium cardiac jelly biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005261 A cardiac jelly that is part of an atrium [Automatically generated definition]. GO:0043820 propionyl-CoA dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043820 EC:1.3.99.- Catalysis of the irreversible NADH-dependent formation of propionyl-CoA from acryloyl-CoA. GO:0043823 spheroidene monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043823 MetaCyc:RXN-10670|RHEA:33027|EC:1.14.15.9 Catalysis of the reaction: spheroidene + O2 = spheroidenone + H2O. GO:0043822 ribonuclease M5 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043822 MetaCyc:3.1.26.8-RXN|EC:3.1.26.8 5S ribosomal maturation nuclease activity|5S ribosomal RNA maturation endonuclease activity|RNase M5 activity Catalysis of the endonucleolytic cleavage of RNA, removing 21 and 42 nucleotides, respectively, from the 5'- and 3'-termini of a 5S-rRNA precursor. GO:0043829 tRNA-specific adenosine-37 deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043829 TAD1|tRNA-specific adenosine deaminase 1|tRNA(Ala)-A37 deaminase activity Catalysis of the reaction: adenosine-37 + H2O = inosine-37 + NH3, in a tRNA-Ala molecule. GO:0043828 tRNA 2-selenouridine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043828 RHEA:42716|MetaCyc:RXN0-2281 YbbB|SelU|B0503 Catalysis of the reaction: 5-methylaminomethyl-2-thiouridine + selenophosphate = 5-methylaminomethyl-2-selenouridine + phosphate (at the wobble position in tRNA). UBERON:0005269 renal cortex vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005269 renal cortex venous system|kidney cortex vein Artery that receives blood from the renal cortex[MP, modified] UBERON:0005268 renal cortex artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005268 renal cortex artery|kidney cortex artery|renal cortex arterial system An artery that supplies the renal cortex. GO:0043830 thiol-driven fumarate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043830 EC:1.3.99.- Catalysis of the reaction: fumarate + coenzyme M + coenzyme B = succinate + coenzyme M + coenzyme B + heterodisulfide. CHEBI:68448 beta-D-GalpNAc-(1->4)-beta-D-GlcpNAc biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68448 GO:0043836 xanthine hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043836 MetaCyc:R127-RXN xanthinase activity Catalysis of the reaction: xanthine + H2O = 4-ureido-5-imidazole carboxylate. UBERON:0005255 pedal digit mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005255 pedal digital ray mesenchyme|hind limb digit mesenchyme|toe mesenchyme|foot digit mesenchyme|finger ray mesenchyme Mesenchyme that is part of a developing toe [Automatically generated definition]. UBERON:0005254 upper leg mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005254 Mesenchyme that is part of a developing hindlimb stylopod [Automatically generated definition]. GO:0043835 obsolete uracil/thymine dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043835 EC:1.17.99.4 uracil-thymine oxidase activity|uracil:acceptor oxidoreductase activity|uracil oxidase activity|uracil/thymine dehydrogenase activity OBSOLETE. Catalysis of the reactions: uracil + H2O + acceptor = barbiturate + reduced acceptor; and thymine + H2O + acceptor = 5-methylbarbiturate + reduced acceptor. UBERON:0005253 head mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005253 desmocranium|cranial mesenchyme|cephalic mesenchyme Portion of primordial embryonic connective tissue of the developing head, consisting of mesenchymal cells supported in interlaminar jelly, that derive mostly from the mesoderm and contribute to head connective tissue, bone and musculature in conjunction with cranial neural crest cells. GO:0043838 phosphatidylethanolamine:Kdo2-lipid A phosphoethanolamine transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043838 phosphoethanolamine transferase|EptB Catalysis of the reaction: Kdo2-lipid A + phosphatidylethanolamine = phosphoethanolamine-Kdo2-lipid A + diacylglycerol. GO:0043837 valine dehydrogenase (NAD) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043837 RHEA:30763|EC:1.4.1.23 ValDH Catalysis of the reaction: L-valine + H2O + NAD+ = 3-methyl-2-oxobutanoate + NH3 + NADH. UBERON:0005251 yolk sac cavity biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005251 yolk sac space|cavity of yolk sac|yolk sac lumen An anatomical cavity that is part of a yolk sac [Automatically generated definition]. GO:0043832 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043832 GO:0043831 thiosulfate dehydrogenase (quinone) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043831 EC:1.8.5.2|KEGG_REACTION:R07177|RHEA:10936|MetaCyc:1.8.5.2-RXN TQO|thiosulphate:quinone oxidoreductase activity|thiosulfate:6-decylubiquinone oxidoreductase activity|thiosulphate dehydrogenase (quinone) activity|thiosulfate:quinone oxidoreductase activity|thiosulfate oxidoreductase, tetrathionate-forming activity|DoxD|DoxA Catalysis of the reaction: 6-decylubiquinone + 2 thiosulfate = 6-decylubiquinol + tetrathionate. UBERON:0005250 stomatodeum gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005250 stomatodaeum gland A gland that is part of a stomodeum. GO:0043834 trimethylamine methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043834 RHEA:39287|EC:2.1.1.250|MetaCyc:RXN-8102 TMA methyltransferase 1|trimethylamine-specific methylcobalamin:coenzyme M methyltransferase activity|MT1|trimethylamine:corrinoid methyltransferase activity|mttB1 Catalysis of the reaction: trimethylamine + a trimethylamine corrinoid protein = a methylated trimethylamine corrinoid protein + dimethylamine. GO:0043833 methylamine-specific methylcobalamin:coenzyme M methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043833 EC:2.1.1.247|MetaCyc:RXN-8103|MetaCyc:RXN-8101|MetaCyc:RXN-8099 methylamine-specific methylcobalamin:CoM methyltransferase activity|methylcobamide:CoM methyltransferase II isozyme A|methylcobamide:coenzyme M methyltransferase activity|monomethylamine-specific methylcobalamin:coenzyme M methyltransferase activity|methylcobamide:CoM methyltransferase activity Catalysis of the reaction: a methylated methylamine corrinoid protein + coenzyme M = a methylamine corrinoid protein + methyl-CoM. This reaction is the transfer of the methyl group from the methylated corrinoid cofactor of a methylamine corrinoid protein to coenzyme M. UBERON:0005259 lower leg mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005259 Mesenchyme that is part of a developing lower leg [Automatically generated definition]. GO:0043839 lipid A phosphate methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043839 lipid A phosphomethyltransferase activity|lipid A methyltransferase|LmtA|lipid A 1-phosphomethyltransferase activity Catalysis of the transfer of a methyl group from S-adenosylmethionine (SAM) to the 1-phosphate group of lipid A. UBERON:0005258 upper arm mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005258 Mesenchyme that is part of a developing forelimb stylopod [Automatically generated definition]. UBERON:0005257 manual digit mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005257 anterior limb digital ray mesenchyme|fore limb digit mesenchyme|finger mesenchyme|manual digital ray mesenchyme|hand digit mesenchyme|finger ray mesenchyme Mesenchyme that is part of a developing finger [Automatically generated definition]. UBERON:0005256 trunk mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005256 trunk and cervical mesenchyme Mesenchyme that is part of a developing trunk. CHEBI:68452 azole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68452 CHEBI:68458 multi-methyl-branched fatty acyl-CoA(4-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68458 GO:0043841 (S)-lactate 2-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043841 MetaCyc:RXN-8076 lactate 2-kinase activity Catalysis of the reaction: (S)-lactate + GTP = 2-phospho-(S)-lactate + GDP. GO:0043840 branched-chain amino acid:2-keto-4-methylthiobutyrate aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043840 MetaCyc:RXN-7708 branched-chain-amino-acid:2-keto-4-methylthiobutyrate aminotransferase activity|branched-chain amino acid aminotransferase|BCAT|branched chain amino acid:2-keto-4-methylthiobutyrate aminotransferase activity Catalysis of the reaction: 2-keto-4-methylthiobutyrate + L-phenylalanine = phenylpyruvate + L-methionine. GO:0043847 DNA polymerase III, clamp loader chi/psi subcomplex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043847 DNA polymerase III, DnaX complex, chi/psi subcomplex A dimer composed of the chi and psi subunits which is a subassembly of the DNA polymerase III clamp loader complex and serves as a bridge between the DnaX complex and the single-stranded DNA-binding protein (SSB). GO:0043846 DNA polymerase III, clamp loader complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043846 clamp loader complex|DNA polymerase III, DnaX complex|DNA polymerase III, DnaX subcomplex A heptamer that includes the tau and gamma products of the dnaX gene and the chi/psi subcomplex. Confers structural asymmetry that allows the polymerase to replicate both leading and lagging strands. UBERON:0005243 interventricular septum endocardium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005243 interventricular septum endocardial tissue|endocardium of interventricular septum An endocardium that is part of a interventricular septum [Automatically generated definition]. GO:0043849 Ras palmitoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043849 Ras protein acyltransferase activity|ERF2|palmitoyltransferase ERF2|DHHC cysteine-rich domain-containing protein ERF2 Catalysis of the reaction: palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA, specific for Ras proteins. GO:0043848 obsolete excinuclease cho activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043848 endonuclease cho|uvrc homolog protein|cho OBSOLETE. Catalysis of the incision of damaged DNA on the 3' side of a lesion, typically at the ninth phosphodiester bond 3' of the damage. GO:0043843 ADP-specific glucokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043843 Reactome:R-HSA-5696021|EC:2.7.1.147|RHEA:11460 ADP-dependent glucokinase activity|ADP:D-glucose 6-phosphotransferase activity Catalysis of the reaction: ADP + D-glucose = AMP + D-glucose 6-phosphate. CHEBI:19418 3-(acetamidomethylene)-2-(hydroxymethyl)succinate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_19418 GO:0043842 Kdo transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043842 MetaCyc:KDOTRANS2-RXN|EC:2.4.99.15|EC:2.4.99.14|MetaCyc:KDOTRANS-RXN|EC:2.4.99.13|EC:2.4.99.12 WaaA|kdtA|3-deoxy-D-manno-octulosonic-acid transferase activity Catalysis of the reactions: (KDO)-lipid IVA + CMP-3-deoxy-D-manno-octulosonate = KDO2-lipid IVA + CMP, and lipid IVA + CMP-3-deoxy-D-manno-octulosonate = (KDO)-lipid IVA + CMP. GO:0043845 DNA polymerase III, proofreading complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043845 DNA polymerase III, proofreading subcomplex|DNA polymerase III, proof-reading subcomplex|DNA polymerase III, proof-reading complex A subcomplex of DNA polymerase III composed of the epsilon subunit which has proofreading activity, and the theta subunit which enhances the epsilon subunit's proofreading activity. GO:0043844 ADP-specific phosphofructokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043844 RHEA:20105|EC:2.7.1.146 ADP-6-phosphofructokinase activity|ADP-dependent phosphofructokinase activity|ADP:D-fructose-6-phosphate 1-phosphotransferase activity|ADP-Pfk activity Catalysis of the reaction: ADP + D-fructose 6-phosphate = AMP + D-fructose 1,6-bisphosphate. UBERON:0005249 metanephric renal pelvis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005249 metanephros pelvis A renal pelvis that is part of a metanephros. UBERON:0005248 bulbus cordis myocardium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005248 bulbus cordis cardiac muscle A myocardium that is part of a bulbus cordis [Automatically generated definition]. GO:0004249 obsolete stromelysin 3 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004249 matrix metalloproteinase 11|MMP-11|stromelysin 3 activity OBSOLETE. Was not defined before being made obsolete. GO:0004246 obsolete peptidyl-dipeptidase A activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004246 EC:3.4.15.1|MetaCyc:3.4.15.1-RXN kininase II activity|angiotensin converting enzyme|ACE activity|endothelial cell peptidyl dipeptidase activity|peptidyl dipeptidase-4|angiotensin I-converting enzyme activity|peptidyl dipeptide hydrolase activity|peptidyl dipeptidase I activity|peptidyl-dipeptidase A activity|peptidyl dipeptidase A|peptidase P activity|dipeptide hydrolase|carboxycathepsin activity|dipeptidyl carboxypeptidase I activity|PDH|peptidyldipeptide hydrolase activity|peptidyl-dipeptide hydrolase activity|DCP OBSOLETE. Catalysis of the release of a C-terminal dipeptide, Xaa-Xbb from oligopeptide-Xaa-Xbb, when Xaa is not Pro, and Xbb is neither Asp nor Glu. Converts angiotensin I to angiotensin II. GO:0004245 obsolete neprilysin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004245 enkephalinase activity|CALLA|neutral metallendopeptidase activity|CD10|CALLA glycoprotein|kidney-brush-border neutral peptidase|kidney-brush-border neutral proteinase activity|acute lymphoblastic leukemia antigen|neutral endopeptidase 24.11|neutral endopeptidase activity|endopeptidase-2 activity|neprilysin activity|common acute lymphoblastic leukemia-associated antigens|endopeptidase 24.11|CALLA (common acute lymphoblastic leukemia-associated) antigens|common acute lymphoblastic leukemia antigen|CALLA glycoproteins|CALLA antigen|kidney-brush-border neutral endopeptidase|membrane metalloendopeptidase activity OBSOLETE. Catalysis of the preferential cleavage at the amino group of hydrophobic residues in insulin, casein, hemoglobin, and a number of other proteins and polypeptides. GO:0004248 obsolete stromelysin 1 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004248 proteoglycanase activity|collagen-activating protein|transin activity|neutral proteoglycanase activity|matrix metalloproteinase 3 activity|procollagenase activator|collagenase activating protein|MMP-3|stromelysin|stromelysin 1 activity OBSOLETE. Catalysis of the preferential cleavage where P1', P2' and P3' are hydrophobic residues. GO:0004247 obsolete saccharolysin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004247 oligopeptidase yscD activity|yeast cysteine proteinase D activity|proteinase yscD activity|saccharolysin activity|saccharomyces cerevisiae proteinase yscD OBSOLETE. Catalysis of the cleavage of Pro-Phe and Ala-Ala bonds. GO:0004242 obsolete beta-mitochondrial processing peptidase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004242 beta-MPP|beta-mitochondrial processing peptidase OBSOLETE. (Was not defined before being made obsolete). GO:0004241 obsolete alpha-mitochondrial processing peptidase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004241 alpha-MPP|alpha-mitochondrial processing peptidase OBSOLETE. (Was not defined before being made obsolete). GO:0004244 obsolete mitochondrial inner membrane peptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004244 IMP|mitochondrial inner membrane peptidase activity OBSOLETE. Catalysis of the maturation of mitochondrial precursor proteins delivered to the intermembrane space. GO:0004243 obsolete mitochondrial intermediate peptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004243 mitochondrial intermediate peptidase activity|mitochondrial intermediate precursor-processing proteinase activity|MIP OBSOLETE. Catalysis of the release of an N-terminal octapeptide as second stage of processing of some proteins imported in the mitochondrion. GO:0004240 obsolete mitochondrial processing peptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004240 alpha-mitochondrial processing peptidase|matrix peptidase|matrix processing proteinase|processing enhancing peptidase activity|mitochondrial protein precursor-processing proteinase activity|processing enhancing peptidase (for one of two subunits)|MPP|matrix processing peptidase|beta-mitochondrial processing peptidase|mitochondrial processing peptidase activity OBSOLETE. Catalysis of the release of N-terminal transit peptides from precursor proteins imported into the mitochondrion, typically with Arg in position P2. GO:0018887 4-carboxy-4'-sulfoazobenzene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018887 UM-BBD_pathwayID:csab 4-carboxy-4'-sulphoazobenzene metabolism|4-carboxy-4'-sulphoazobenzene metabolic process|4-carboxy-4'-sulfoazobenzene metabolism The chemical reactions and pathways involving 4-carboxy-4'-sulfoazobenzene, a sulfonated azo compound synthesized by nitro-amine condensation from sulfanilic acid and 4-nitrobenzoic acid. GO:0018886 anaerobic carbon tetrachloride metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018886 UM-BBD_pathwayID:ctc anaerobic carbon tetrachloride metabolism The chemical reactions and pathways involving carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations, that occur in the absence of oxygen. GO:0018889 2-chloro-N-isopropylacetanilide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018889 UM-BBD_pathwayID:ppc 2-chloro-N-isopropylacetanilide metabolism|propachlor metabolic process|propachlor metabolism The chemical reactions and pathways involving 2-chloro-N-isopropylacetanilide, an acylanide herbicide widely used to protect corn, onion, cabbage, rose bushes, and ornamental plants. GO:0018888 3-chloroacrylic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018888 UM-BBD_pathwayID:caa 3-chloroacrylic acid metabolism The chemical reactions and pathways involving 3-chloroacrylic acid, ClHC=CHCOOH, a chlorinated derivative of acrylic acid. GO:0018883 caprolactam metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018883 UM-BBD_pathwayID:cap caprolactam metabolism The chemical reactions and pathways involving caprolactam, hexahydro-2h-azepin-2-one, a cyclic amide of caproic acid used in manufacture of synthetic fibers of the polyamide type. It can cause local irritation. GO:0018882 (+)-camphor metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018882 UM-BBD_pathwayID:cam camphor metabolic process|(+)-camphor metabolism|camphor metabolism The chemical reactions and pathways involving (+)-camphor, a bicyclic monoterpene ketone which is one of the major components in the leaves of common sage. Camphor exists in two enantiomers, but the (+)-isomer is more widely distributed. GO:0018885 carbon tetrachloride metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018885 UM-BBD_pathwayID:ctc carbon tetrachloride metabolism The chemical reactions and pathways involving carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations. It is also used as grain fumigant and a chemical intermediate in the production of refrigerants. GO:0018884 carbazole metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018884 UM-BBD_pathwayID:car carbazole metabolism|CAR metabolic process|CAR metabolism The chemical reactions and pathways involving carbazole, a heterocyclic aromatic compound containing a dibenzopyrrole system that is produced during coal gasification and is present in cigarette smoke. Coal tar produced at high temperature contains an average of 1.5% carbazole. It is used widely in synthesis of dyes, pharmaceuticals, and plastics and is a suspected carcinogen. GO:0018881 bromoxynil metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018881 UM-BBD_pathwayID:box bromoxynil metabolism The chemical reactions and pathways involving bromoxynil, C7H3Br2NO, a dibrominated phenol derivative with a cyano (-CN) group attached. Bromoxynil is used as a herbicide for post-emergent control of annual broadleaf weeds and works by inhibiting photosynthesis in the target plants. GO:0018880 4-chlorobiphenyl metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018880 UM-BBD_pathwayID:cbp 4-chlorobiphenyl metabolism The chemical reactions and pathways involving 4-chlorobiphenyl, a member of the polychlorinated biphenyl (PCB) group of compounds, a very stable group of synthetic organic compounds composed of a biphenyl nucleus with 1-10 chlorine substituents. 4-chlorobiphenyl has been used as a model substrate to investigate PCB degradation. GO:0004258 obsolete vacuolar carboxypeptidase Y biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004258 vacuolar carboxypeptidase Y OBSOLETE. Catalysis of the release of a C-terminal amino acid with a broad specificity. GO:0004253 obsolete gamma-renin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004253 gamma-renin activity OBSOLETE. Catalysis of the cleavage of the Leu-Leu bond in synthetic tetradecapeptide renin substrate, producing angiotensin I, but not active on natural angiotensinogen. Also hydrolyzes BZ-Arg-para-nitroanilide. GO:0004252 serine-type endopeptidase activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0004252 Reactome:R-HSA-2514772|Reactome:R-HSA-9023626|Reactome:R-HSA-381466|Reactome:R-HSA-6801687|Reactome:R-HSA-3266557|Reactome:R-HSA-140736|Reactome:R-HSA-2471842|Reactome:R-HSA-1566981|Reactome:R-HSA-2471621|Reactome:R-HSA-140664|Reactome:R-HSA-8874204|Reactome:R-HSA-1604690|Reactome:R-HSA-159868|Reactome:R-HSA-158313|Reactome:R-HSA-381461|Reactome:R-HSA-158333|Reactome:R-HSA-158164|Reactome:R-HSA-977615|Reactome:R-HSA-166753|Reactome:R-HSA-5607002|Reactome:R-HSA-9023627|Reactome:R-HSA-166817|Reactome:R-HSA-2172405|Reactome:R-HSA-1592297|Reactome:R-HSA-158750|Reactome:R-HSA-173745|Reactome:R-HSA-158766|Reactome:R-HSA-1474197|Reactome:R-HSA-140777|Reactome:R-HSA-381500|EC:3.4.21.39|Reactome:R-HSA-8874206|Reactome:R-HSA-8874205|Reactome:R-HSA-381798|Reactome:R-HSA-174551|Reactome:R-HSA-9023178|Reactome:R-HSA-1604752|EC:3.4.21.27|Reactome:R-HSA-9686710|EC:3.4.21.38|Reactome:R-HSA-977371|Reactome:R-HSA-1592278|Reactome:R-HSA-158925|Reactome:R-HSA-9668253|Reactome:R-HSA-1592398|Reactome:R-HSA-2534206|Reactome:R-HSA-2482180|Reactome:R-HSA-158311|Reactome:R-HSA-159733|EC:3.4.21.26|EC:3.4.21.48|EC:3.4.21.59|Reactome:R-HSA-9686731|Reactome:R-HSA-9033530|Reactome:R-HSA-9694661|Reactome:R-HSA-2168960|Reactome:R-HSA-9668365|Reactome:R-HSA-1566962|EC:3.4.21.47|EC:3.4.21.36|EC:3.4.21.69|Reactome:R-HSA-8874212|Reactome:R-HSA-140599|Reactome:R-HSA-1604741|Reactome:R-HSA-9694287|Reactome:R-HSA-265301|Reactome:R-HSA-6800299|Reactome:R-HSA-400459|EC:3.4.21.46|EC:3.4.21.35|EC:3.4.21.79|EC:3.4.21.68|Reactome:R-HSA-163798|Reactome:R-HSA-159728|EC:3.4.21.89|Reactome:R-HSA-1592371|Reactome:R-HSA-976743|Reactome:R-HSA-9033520|EC:3.4.21.45|EC:3.4.21.34|EC:3.4.21.78|EC:3.4.21.88|EC:3.4.21.22|Reactome:R-HSA-9033524|Reactome:R-HSA-140700|EC:3.4.21.87|Reactome:R-HSA-166792|Reactome:R-HSA-9033490|Reactome:R-HSA-8849857|EC:3.4.21.21|EC:3.4.21.10|EC:3.4.21.54|EC:3.4.21.43|Reactome:R-HSA-1799329|Reactome:R-HSA-140696|Reactome:R-HSA-163843|Reactome:R-HSA-158419|Reactome:R-HSA-1602466|Reactome:R-HSA-173680|Reactome:R-HSA-381135|EC:3.4.24.34|EC:3.4.19.1|EC:3.4.21.20|EC:3.4.21.53|EC:3.4.21.42|EC:3.4.21.75|Reactome:R-HSA-1602488|EC:3.4.24.7|Reactome:R-HSA-400496|Reactome:R-HSA-140840|Reactome:R-HSA-6807224|Reactome:R-HSA-1912369|EC:3.4.21.41|Reactome:R-HSA-1604368|EC:3.4.21.9|Reactome:R-HSA-2534260|Reactome:R-HSA-3788061|Reactome:R-HSA-5210935|Reactome:R-HSA-8874186|EC:3.4.21.73|EC:3.4.21.62|Reactome:R-HSA-9023633|Reactome:R-HSA-2534160|Reactome:R-HSA-158137|Reactome:R-HSA-158942|Reactome:R-HSA-1181152|Reactome:R-HSA-141026|Reactome:R-HSA-9653249|EC:3.4.21.94|EC:3.4.21.83|Reactome:R-HSA-1566979|EC:3.4.21.61|Reactome:R-HSA-3814820|MetaCyc:ACYLAMINOACYL-PEPTIDASE-RXN|Reactome:R-HSA-6800200|Reactome:R-HSA-422051|EC:3.4.21.7|Reactome:R-HSA-400492|EC:3.4.21.93|Reactome:R-HSA-3785684|EC:3.4.21.71|Reactome:R-HSA-1592314|EC:3.4.24.3|EC:3.4.21.6|Reactome:R-HSA-5210912|EC:3.4.21.92|Reactome:R-HSA-159796|Reactome:R-HSA-1592436|Reactome:R-HSA-8865276|Reactome:R-HSA-1592270|Reactome:R-HSA-6800198|EC:3.4.21.5|Reactome:R-HSA-183130|Reactome:R-HSA-9655046|Reactome:R-HSA-159773|Reactome:R-HSA-158744|Reactome:R-HSA-158300|Reactome:R-HSA-5578783|Reactome:R-HSA-9670874|Reactome:R-HSA-5691512|EC:3.4.21.4|Reactome:R-HSA-5591040|Reactome:R-HSA-1592362|EC:3.4.21.102|Reactome:R-HSA-1604731|Reactome:R-HSA-183122|Reactome:R-HSA-8865275|Reactome:R-HSA-9033515|Reactome:R-HSA-158982|Reactome:R-HSA-8855825|Reactome:R-HSA-1602473|Reactome:R-HSA-159771|Reactome:R-HSA-1604722|Reactome:R-HSA-9699007|Reactome:R-HSA-173626|Reactome:R-HSA-1604732|Reactome:R-HSA-9023632|Reactome:R-HSA-2514823|Reactome:R-HSA-1602458|Reactome:R-HSA-8852716|Reactome:R-HSA-114697|Reactome:R-HSA-170844|Reactome:R-HSA-187020|EC:3.4.21.1|Reactome:R-HSA-2168923|Reactome:R-HSA-141040|Reactome:R-HSA-1604712|Reactome:R-HSA-8850831|Reactome:R-HSA-9662786|Reactome:R-HSA-1604360|Reactome:R-HSA-186785|Reactome:R-HSA-140769|Reactome:R-HSA-9023196|Reactome:R-HSA-1602484|Reactome:R-HSA-382061|Reactome:R-HSA-3928657|Reactome:R-HSA-422021|Reactome:R-HSA-171288|Reactome:R-HSA-1604763|Reactome:R-HSA-139893|Reactome:R-HSA-140870|Reactome:R-HSA-1454843|Reactome:R-HSA-1912372|Reactome:R-HSA-9033529|Reactome:R-HSA-381446|Reactome:R-HSA-1655842|Reactome:R-HSA-8849826|Reactome:R-HSA-2214330|Reactome:R-HSA-158747|Reactome:R-HSA-1604359|Reactome:R-HSA-173631|Reactome:R-HSA-140823|Reactome:R-HSA-1592316|Reactome:R-HSA-9673223|Reactome:R-HSA-9033506|EC:3.4.21.-|Reactome:R-HSA-2022411|Reactome:R-HSA-2129357|Reactome:R-HSA-9666383 serine elastase activity|blood coagulation factor activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine). GO:0004254 obsolete acylaminoacyl-peptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004254 acylamino-acid-releasing enzyme activity|acylaminoacyl-peptidase activity|N-formylmethionine (fMet) aminopeptidase activity|alpha-N-acylpeptide hydrolase activity|N-acylpeptide hydrolase activity OBSOLETE. Catalysis of the reaction: acylaminoacyl-peptide + H2O = acylamino acid + peptide. GO:0004251 obsolete X-Pro dipeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004251 EC:3.4.13.9|MetaCyc:3.4.13.9-RXN gamma-peptidase activity|prolidase activity|proline dipeptidase activity|Xaa-Pro dipeptidase activity|X-Pro dipeptidase activity|imidodipeptidase activity|peptidase D OBSOLETE. Catalysis of the hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on Pro-Pro. CHEBI:44485 N-ethylmaleimide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_44485 GO:0004250 obsolete aminopeptidase I activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004250 MetaCyc:3.4.11.22-RXN|EC:3.4.11.22 aminopeptidase yscI activity|vacuolar aminopeptidase I activity|aminopeptidase I activity|yeast aminopeptidase I|leucine aminopeptidase IV activity|aminopeptidase III activity OBSOLETE. Catalysis of the release of an N-terminal amino acid, preferably a neutral or hydrophobic one, from a polypeptide. Aminoacyl-arylamides are poor substrates. GO:0018898 2,4-dichlorobenzoate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018898 UM-BBD_pathwayID:dcb 2,4-dichlorobenzoate metabolism The chemical reactions and pathways involving 2,4-dichlorobenzoate, a chlorinated aromatic compound which is a key intermediate in the aerobic degradation of polychlorinated biphenyls (PCBs). GO:0018897 dibenzothiophene desulfurization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018897 UM-BBD_pathwayID:dbt|MetaCyc:PWY-681 dibenzothiophene desulphurization The removal of the sulfur atom from dibenzothiophene, a substance composed of two benzene rings linked by one sulfide bond and one carbon-carbon bond. GO:0018899 1,2-dichloroethane metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018899 UM-BBD_pathwayID:dce 1,2-dichloroethane metabolism The chemical reactions and pathways involving 1,2-dichloroethane, a major commodity chemical used, for example, in the manufacture of vinyl chloride. GO:0018894 dibenzo-p-dioxin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018894 UM-BBD_pathwayID:dpd oxanthrene metabolic process|oxanthrene metabolism|phenodioxin metabolism|dibenzo-p-dioxin metabolism|phenodioxin metabolic process The chemical reactions and pathways involving dibenzo-p-dioxin, a substance composed of two benzene rings linked by two ether bonds. Dibenzo-p-dioxins are generated as by-products in the manufacturing of herbicides, insecticides, fungicides, paper pulp bleaching, and in incineration, and can accumulate in milk and throughout the food chain, creating significant health concern. GO:0018893 dibenzofuran metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018893 UM-BBD_pathwayID:dbf dibenzofuran metabolism The chemical reactions and pathways involving dibenzofuran, a substance composed of two benzene rings linked by one ether bond and one carbon-carbon bond. Dibenzofuran is a white crystalline solid created from the production of coal tar and used as an insecticide and an intermediate in the production of other chemicals. GO:0018896 dibenzothiophene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018896 UM-BBD_pathwayID:dbt2 dibenzothiophene catabolism|dibenzothiophene degradation|dibenzothiophene breakdown The chemical reactions and pathways resulting in the breakdown of dibenzothiophene, a substance composed of two benzene rings linked by one sulfide bond and one carbon-carbon bond. GO:0018895 dibenzothiophene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018895 dibenzothiophene metabolism|diphenylene sulfide metabolism|diphenylene sulfide metabolic process The chemical reactions and pathways involving dibenzothiophene, a substance composed of two benzene rings linked by one sulfide bond and one carbon-carbon bond. Dibenzothiophene derivatives can be detected in diesel oil following hydrodesulfurization treatment to remove sulfur compounds that would otherwise generate sulfur oxides during combustion. GO:0018890 cyanamide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018890 UM-BBD_pathwayID:cnm cyanamide metabolism The chemical reactions and pathways involving cyanamide, NCNH2, a cyanide compound which has been used as a fertilizer, defoliant and in many manufacturing processes. It often occurs as the calcium salt, sometimes also referred to as cyanamide. The citrated calcium salt is used in the treatment of alcoholism. GO:0018892 cyclohexylsulfamate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018892 UM-BBD_pathwayID:chs cyclohexylsulfamate metabolism|cyclohexylsulphamate metabolism|cyclohexylsulphamate metabolic process The chemical reactions and pathways involving cyclohexylsulfamate, also known as cyclamic acid. Sodium cyclohexylsulfamate (CHS-Na) was a widely used sweetening agent but was banned because of the suspicion of carcinogenicity and metabolic conversion to cyclohexylamine (CHA), a toxic substance. It is now used as a fungicide. GO:0018891 cyclohexanol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018891 UM-BBD_pathwayID:chx cyclohexanol metabolism The chemical reactions and pathways involving cyclohexanol, the monohydroxy derivative of cyclohexane. It is used as a solvent and blending agent. GO:0004228 obsolete gelatinase A activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004228 collagenase type IV|gelatinase A activity|type IV collagenase activity|MMP 2|72-kDa gelatinase activity|matrix metalloproteinase 2 activity|3/4 collagenase activity|type IV collagenase/gelatinase activity|type IV collagen metalloproteinase|MMP-2|collagenase IV|72 kDa gelatinase type A|matrix metalloproteinase 5 OBSOLETE. Catalysis of the cleavage of gelatin type I and collagen types IV, V, VII, X. Cleaves the collagen-like sequence Pro-Gln-Gly-Ile-Ala-Gly-Gln at the Gly-Ile bond. GO:0004229 obsolete gelatinase B activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004229 collagenase type IV|MMP 9|macrophage gelatinase activity|type V collagenase activity|gelatinase B activity|95 kDa type IV collagenase/gelatinase activity|MMP-9|92-kDa gelatinase activity|type IV collagen metalloproteinase|matrix metalloproteinase 9 activity|92-kDa type IV collagenase activity|gelatinase MMP 9|collagenase IV OBSOLETE. Catalysis of the cleavage of gelatin types I and V and collagen types IV and V. GO:0004226 obsolete Gly-X carboxypeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004226 Gly-Xaa carboxypeptidase activity|yeast carboxypeptidase activity|glycine carboxypeptidase activity|Gly-X carboxypeptidase activity|carboxypeptidase S activity|carboxypeptidase a|peptidase alpha OBSOLETE. Catalysis of the reaction: peptidyl-Gly-Xaa + H2O = peptidyl-Gly + Xaa. GO:0004220 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0004220 GO:0004222 metalloendopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004222 Reactome:R-HSA-1564120|MetaCyc:3.4.24.11-RXN|MetaCyc:3.4.24.22-RXN|Reactome:R-HSA-1592310|MetaCyc:3.4.24.55-RXN|Reactome:R-HSA-194818|Reactome:R-HSA-3828025|EC:3.4.24.37|EC:3.4.24.59|Reactome:R-HSA-2485111|MetaCyc:3.4.24.21-RXN|Reactome:R-HSA-381435|MetaCyc:3.4.24.64-RXN|Reactome:R-HSA-8874201|EC:3.4.24.14|EC:3.4.24.69|Reactome:R-HSA-3791155|Reactome:R-HSA-1299476|Reactome:R-HSA-2534248|Reactome:R-HSA-2533874|EC:3.4.24.24|EC:3.4.24.35|EC:3.4.24.57|Reactome:R-HSA-5250978|Reactome:R-HSA-1251992|Reactome:R-HSA-2473596|Reactome:R-HSA-1474213|Reactome:R-HSA-8867344|Reactome:R-HSA-2534240|EC:3.4.24.23|EC:3.4.24.56|Reactome:R-HSA-8942302|Reactome:R-HSA-8874187|Reactome:R-HSA-8874192|EC:3.4.24.11|EC:3.4.24.22|Reactome:R-HSA-4086205|EC:3.4.24.55|MetaCyc:3.4.24.61-RXN|MetaCyc:3.4.24.72-RXN|Reactome:R-HSA-1564112|Reactome:R-HSA-2473584|Reactome:R-HSA-5250606|Reactome:R-HSA-1564164|Reactome:R-HSA-1474210|Reactome:R-HSA-2022141|EC:3.4.24.21|Reactome:R-HSA-2484882|Reactome:R-HSA-1564179|MetaCyc:3.4.24.71-RXN|EC:3.4.24.64|Reactome:R-HSA-8874194|MetaCyc:3.4.24.70-RXN|Reactome:R-HSA-4224014|Reactome:R-HSA-6784620|Reactome:R-HSA-1458433|Reactome:R-HSA-5250962|Reactome:R-HSA-8874195|Reactome:R-HSA-194808|EC:3.4.24.61|EC:3.4.24.72|Reactome:R-HSA-2533965|EC:3.4.24.71|Reactome:R-HSA-194809|Reactome:R-HSA-194800|Reactome:R-HSA-1564142|Reactome:R-HSA-2485148|Reactome:R-HSA-2168982|EC:3.4.24.70|Reactome:R-HSA-1564169|Reactome:R-HSA-9624272|Reactome:R-HSA-2473594|Reactome:R-HSA-5250892|Reactome:R-HSA-381537|Reactome:R-HSA-8949649|Reactome:R-HSA-264758|Reactome:R-HSA-1474196|Reactome:R-HSA-2514831|Reactome:R-HSA-194793|Reactome:R-HSA-2537499|Reactome:R-HSA-8876868|Reactome:R-HSA-1655851|EC:3.4.24.-|Reactome:R-HSA-8940561|Reactome:R-HSA-8940554|Reactome:R-HSA-8943959|Reactome:R-HSA-3788075|Reactome:R-HSA-2533970|Reactome:R-HSA-381518|Reactome:R-HSA-2168046|Reactome:R-HSA-8949659|Reactome:R-HSA-181567|Reactome:R-HSA-2533950|Reactome:R-HSA-177946|Reactome:R-HSA-5694082|Reactome:R-HSA-2514790|MetaCyc:3.4.24.19-RXN|Reactome:R-HSA-1564117|Reactome:R-HSA-2002440|MetaCyc:3.4.24.18-RXN|Reactome:R-HSA-8877620|MetaCyc:3.4.24.17-RXN|Reactome:R-HSA-1564143|Reactome:R-HSA-2002428|Reactome:R-HSA-194796|Reactome:R-HSA-5362793|Reactome:R-HSA-3791295|Reactome:R-HSA-8949668|Reactome:R-HSA-1564184|MetaCyc:3.4.24.59-RXN|Reactome:R-HSA-3791149|Reactome:R-HSA-3371385|Reactome:R-HSA-2179402|Reactome:R-HSA-1299478|Reactome:R-HSA-2533944|Reactome:R-HSA-1454757|MetaCyc:3.4.24.37-RXN|Reactome:R-HSA-3791319|Reactome:R-HSA-1454822|Reactome:R-HSA-5333671|MetaCyc:3.4.24.69-RXN|EC:3.4.24.19|MetaCyc:3.4.24.14-RXN|Reactome:R-HSA-5228578|Reactome:R-HSA-8940959|MetaCyc:3.4.24.24-RXN|Reactome:R-HSA-8940641|MetaCyc:3.4.24.35-RXN|Reactome:R-HSA-3827958|MetaCyc:3.4.24.57-RXN|EC:3.4.24.18|Reactome:R-HSA-420818|Reactome:R-HSA-1168777|MetaCyc:3.4.24.23-RXN|EC:3.4.24.17|MetaCyc:3.4.24.56-RXN metalloendoproteinase activity|metalloendoprotease activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. GO:0004221 obsolete ubiquitin thiolesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004221 MetaCyc:UBIQUITIN-THIOLESTERASE-RXN|KEGG_REACTION:R02418 ubiquitin-C-terminal-thioester hydrolase activity|ubiquitin carboxy-terminal esterase activity|ubiquitin thioesterase activity|ubiquitin C-terminal hydrolase activity|ubiquitin carboxy-terminal hydrolase activity|ubiquitin thiolesterase activity|ubiquitinyl hydrolase 1 activity OBSOLETE. Catalysis of the reaction: ubiquitin C-terminal thioester + H2O = ubiquitin + a thiol. GO:0018869 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018869 GO:0018868 2-aminobenzenesulfonate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018868 UM-BBD_pathwayID:abs 2-aminobenzenesulphonate metabolism|2-aminobenzenesulphonate metabolic process|2-aminobenzenesulfonate metabolism The chemical reactions and pathways involving 2-aminobenzenesulfonate, aniline-o-sulfonic acid, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines. CHEBI:138844 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138844 CHEBI:138843 3-oxo bile acid CoA thioester(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138843 CHEBI:138842 3alpha-hydroxy bile acid CoA thioester(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138842 GO:0018865 acrylonitrile metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018865 UM-BBD_pathwayID:acr acrylonitrile metabolism The chemical reactions and pathways involving acrylonitrile, a colorless, volatile liquid with a pungent odor. Acrylonitrile is used in the production of acrylic fibers, plastics, and synthetic rubbers. GO:0018864 acetylene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018864 UM-BBD_pathwayID:atl ethyne metabolism|acetylene metabolism|ethyne metabolic process The chemical reactions and pathways involving acetylene, formula CH2CH2, the simplest of the alkynes. GO:0018867 alpha-pinene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018867 UM-BBD_pathwayID:apn alpha-pinene metabolism The chemical reactions and pathways involving alpha-pinene, a monoterpene that may be a significant factor affecting bacterial activities in nature. It is a major component in tea-tree oils, and gives off a piney smelling odor. GO:0018866 adamantanone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018866 UM-BBD_pathwayID:ada adamantanone metabolism The chemical reactions and pathways involving adamantanone, tricyclo(3.3.1.13,7)decanone, a white crystalline solid used as an intermediate for microelectronics in the production of photoresists. GO:0018861 4-chlorobenzoate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018861 UM-BBD_reactionID:r0139|KEGG_REACTION:R03932|EC:6.2.1.33|RHEA:23220|MetaCyc:6.2.1.33-RXN 4-chlorobenzoate:CoA ligase activity Catalysis of the reaction: 4-chlorobenzoate + CoA + ATP = 4-chlorobenzoyl-CoA + AMP + diphosphate. This reaction requires magnesium and is part of the bacterial 2,4-dichlorobenzoate degradation pathway. GO:0018860 anthranilate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018860 KEGG_REACTION:R00982|UM-BBD_reactionID:r0341|EC:6.2.1.32|MetaCyc:AMINOBENZCOALIG-RXN|RHEA:10828 anthraniloyl coenzyme A synthetase activity|2-aminobenzoate-coenzyme A ligase activity|anthranilate--CoA ligase activity|2-aminobenzoate-CoA ligase activity|2-aminobenzoate coenzyme A ligase activity|anthranilate:CoA ligase (AMP-forming) Catalysis of the reaction: ATP + anthranilate + CoA = AMP + diphosphate + anthranilyl-CoA. GO:0018863 phenanthrene-9,10-epoxide hydrolase (9S,10S-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018863 UM-BBD_reactionID:r0496|EC:3.3.2.- Catalysis of the reaction: phenanthrene-9,10-oxide + H2O = trans-9(S),10(S)-dihydrodiolphenanthrene. GO:0018862 phenylphosphate carboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018862 MetaCyc:PHENYLPCARB-RXN|UM-BBD_reactionID:r0157|EC:6.4.1.- Catalysis of the reaction: phenylphosphate + CO2 + H2O = H+ + phosphate + 4-hydroxybenzoate. GO:0004239 obsolete methionyl aminopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004239 MetaCyc:3.4.11.18-RXN|EC:3.4.11.18 peptidase M activity|MAP|methionyl aminopeptidase activity|L-methionine aminopeptidase activity|methionine aminopeptidase activity OBSOLETE. Catalysis of the release of N-terminal amino acids, preferentially methionine, from peptides and arylamides. GO:0004238 obsolete meprin A activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004238 endopeptidase-2 activity|N-benzoyl-L-tyrosyl-p-aminobenzoic acid hydrolase activity|meprin A activity|meprin-a|PPH|PABA-peptide hydrolase activity|meprin OBSOLETE. Catalysis of the hydrolysis of protein and peptide substrates preferentially on carboxyl side of hydrophobic residues. GO:0004235 obsolete matrilysin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004235 matrin activity|metalloproteinase pump-1|MMP|PUMP-1 activity|uterine metalloendopeptidase activity|PUMP-1 proteinase activity|PUMP|MMP 7|matrilysin activity|MMP-7|putative metalloproteinase activity|putative (or punctuated) metalloproteinase-1 activity|matrix metalloproteinase pump 1|matrix metalloproteinase 7 activity OBSOLETE. Catalysis of the cleavage of Ala14-Leu15 and Tyr16-Leu17 in B chain of insulin. No action on collagen types I, II, IV and V. Cleaves gelatin chain alpha-2(I) > alpha-1(I). GO:0004234 obsolete macrophage elastase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004234 MetaCyc:3.4.24.65-RXN|EC:3.4.24.65 human macrophage metalloelastase (HME)|macrophage elastase activity|metalloesterase activity|metalloelastase activity|MMP-12|matrix metalloproteinase 12 activity OBSOLETE. Catalysis of the hydrolysis of soluble and insoluble elastin. Specific cleavages are also produced at Ala14-Leu15 and Tyr16-Leu17 in the B chain of insulin. GO:0004237 obsolete membrane dipeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004237 MetaCyc:3.4.13.19-RXN|EC:3.4.13.19 dipeptidyl hydrolase activity|microsomal dipeptidase activity|dehydropeptidase I (DPH I)|dipeptide hydrolase|glycosyl-phosphatidylinositol-anchored renal dipeptidase activity|MDP|renal dipeptidase activity|membrane dipeptidase activity|dehydropeptidase I activity|nonspecific dipeptidase activity|DPH I activity|aminodipeptidase activity OBSOLETE. Catalysis of the hydrolysis of dipeptides. GO:0004231 obsolete insulysin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004231 insulin-degrading neutral proteinase activity|insulin-glucagon protease activity|insulysin activity|insulin-specific protease activity|IDE|insulin proteinase activity|insulinase activity|insulin protease activity|insulin-degrading enzyme activity|metalloinsulinase activity OBSOLETE. Catalysis of the degradation of insulin, glucagon and other polypeptides. No action on proteins. CHEBI:6809 methamphetamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_6809 GO:0004230 obsolete glutamyl aminopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004230 MetaCyc:3.4.11.7-RXN|EC:3.4.11.7 glutamyl aminopeptidase activity|aspartate aminopeptidase activity|L-aspartate aminopeptidase activity|angiotensinase A|angiotensinase A2|antigen BP-1/6C3 of mouse B lymphocytes|membrane aminopeptidase II|glutamyl peptidase activity|Ca2+-activated glutamate aminopeptidase activity|aminopeptidase A OBSOLETE. Catalysis of the release of a N-terminal glutamate (and to a lesser extent aspartate) from a peptide. GO:0004232 obsolete interstitial collagenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004232 MMP-1|matrix metalloproteinase 1|interstitial collagenase activity|vertebrate collagenase activity OBSOLETE. Catalysis of the preferential cleavage of one bond in native collagen. Cleavage of the triple helix of collagen at about three-quarters of the length of the molecule from the N-terminus, at Gly775-Ile776 in the alpha-1(I) chain. Cleaves synthetic substrates and alpha-macroglobulins at bonds where P1' is a hydrophobic residue. CHEBI:6801 metformin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_6801 GO:0018879 biphenyl metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018879 UM-BBD_pathwayID:bph xenene metabolic process|xenene metabolism|biphenyl metabolism The chemical reactions and pathways involving biphenyl, a toxic aromatic hydrocarbon used as a heat transfer agent, as a fungistat in packaging citrus fruits and in plant disease control. Biphenyl can be chlorinated with 1-10 chlorine molecules to form polychlorinated biphenyls (PCBs). GO:0018876 benzonitrile metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018876 UM-BBD_pathwayID:bzn benzonitrile metabolism The chemical reactions and pathways involving benzonitrile. Benzonitrile is used as a solvent and chemical intermediate in the pharmaceutical, dyestuffs and rubber industries. It is highly toxic and harmful in contact with skin. GO:0018875 anaerobic benzoate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018875 UM-BBD_pathwayID:benz|MetaCyc:CENTBENZCOA-PWY anaerobic benzoate metabolism The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid) that occur in the absence of oxygen. GO:0018878 aerobic beta-1,2,3,4,5,6-hexachlorocyclohexane metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018878 aerobic beta-1,2,3,4,5,6-hexachlorocyclohexane metabolism The chemical reactions and pathways involving beta-1,2,3,4,5,6-hexachlorocyclohexane that occur in presence of oxygen. GO:0018877 beta-1,2,3,4,5,6-hexachlorocyclohexane metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018877 UM-BBD_pathwayID:hch beta-1,2,3,4,5,6-hexachlorocyclohexane metabolism The chemical reactions and pathways involving beta-1,2,3,4,5,6-hexachlorocyclohexane, a halogenated organic insecticide that has been used worldwide for agriculture and public health. GO:0018872 arsonoacetate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018872 UM-BBD_pathwayID:ara arsonoacetate metabolism The chemical reactions and pathways involving arsonoacetate, a synthetic, organic compound containing a single arsenic atom. Arsonoacetate and other arsenic containing compounds are used in agricultural applications as animal feed additives, cotton defoliants and post-emergence grass herbicides. GO:0018871 1-aminocyclopropane-1-carboxylate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018871 UM-BBD_pathwayID:acp 1-aminocyclopropane-1-carboxylate metabolism|ACP metabolism|ACP metabolic process The chemical reactions and pathways involving 1-aminocyclopropane-1-carboxylate, the anion of 1-aminocyclopropane-1-carboxylic acid, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants. GO:0018874 benzoate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018874 UM-BBD_pathwayID:benz2|MetaCyc:P321-PWY benzoate metabolism The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid), a fungistatic compound widely used as a food preservative; it is conjugated to glycine in the liver and excreted as hippuric acid. GO:0018873 atrazine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018873 UM-BBD_pathwayID:atr atrazine metabolism The chemical reactions and pathways involving atrazine, a triazine ring-containing compound, widely used as a herbicide. GO:0018870 anaerobic 2-aminobenzoate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018870 UM-BBD_pathwayID:abz anaerobic 2-aminobenzoate metabolism The chemical reactions and pathways resulting in the breakdown of 2-aminobenzoate, a derivative of benzoic acid with an NH2 group attached to C2, that occurs in the absence of oxygen. GO:0004206 obsolete caspase-10 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004206 caspase-10 activity OBSOLETE. (Was not defined before being made obsolete). GO:0004205 obsolete caspase-8 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004205 caspase-8 activity OBSOLETE. (Was not defined before being made obsolete). GO:0004208 obsolete caspase-3 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004208 caspase-3 activity OBSOLETE. Catalysis of the cleavage at the terminal bond of the motif: Asp-Xaa-Xaa-Asp-Xaa. Enzymes with this function are members of the peptidase family C14 and they appear to function in the inactivation of proteins involved in cellular repair and homeostasis during the effector stage of apoptosis. CHEBI:20485 4-pyridones biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20485 GO:0004207 obsolete effector caspase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004207 effector caspase activity OBSOLETE. (Was not defined before being made obsolete). GO:0004202 obsolete caspase-2 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004202 caspase-2 activity OBSOLETE. (Was not defined before being made obsolete). GO:0004201 obsolete caspase-1 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004201 ICE|caspase-1 activity OBSOLETE. Catalysis of the release of interleukin 1-beta by specific cleavage of Asp116-Ala117 and Asp27-Gly28 bonds in precursor. Enzymes with this function can also hydrolyze the terminal bond in the small-molecule substrate, Ac-Tyr-Val-Ala-Asp-NHMec. GO:0004204 obsolete caspase-5 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004204 caspase-5 activity OBSOLETE. (Was not defined before being made obsolete). GO:0004203 obsolete caspase-4 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004203 caspase-4 activity OBSOLETE. (Was not defined before being made obsolete). GO:0004200 obsolete signaling (initiator) caspase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004200 signaling (initiator) caspase activity|signalling (initiator) caspase activity OBSOLETE. (Was not defined before being made obsolete). GO:0018847 alpha-pinene lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018847 UM-BBD_reactionID:r0712|EC:5.5.1.- Catalysis of the reaction: alpha-pinene = limonene. GO:0018846 styrene-oxide isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018846 EC:5.3.99.7|RHEA:21604|KEGG_REACTION:R02615|MetaCyc:STYRENE-OXIDE-ISOMERASE-RXN|UM-BBD_reactionID:r0034 styrene-oxide isomerase (epoxide-cleaving)|SOI activity|styrene oxide isomerase activity Catalysis of the reaction: styrene oxide = phenylacetaldehyde. GO:0018849 muconate cycloisomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018849 UM-BBD_enzymeID:e0133|MetaCyc:MUCONATE-CYCLOISOMERASE-RXN|RHEA:10640|EC:5.5.1.1 2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing)|muconate lactonizing enzyme activity|muconate cycloisomerase I activity|cis,cis-muconate-lactonizing enzyme|cis,cis-muconate lactonizing enzyme I activity|4-carboxymethyl-4-hydroxyisocrotonolactone lyase (decyclizing)|cis,cis-muconate cycloisomerase activity Catalysis of the reaction: 2,5-dihydro-5-oxofuran-2-acetate = cis,cis-hexadienedioate. GO:0018848 pinocarveol isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018848 UM-BBD_reactionID:r0715|EC:5.5.1.- Catalysis of the reaction: pinocarveol = carveol. GO:0018843 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018843 GO:0018842 3-carboxymuconate cycloisomerase type II activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018842 UM-BBD_reactionID:r0582|EC:5.5.1.2 Catalysis of the reaction: 3-sulfomuconate = 4-sulfolactone. GO:0018845 2-hydroxychromene-2-carboxylate isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018845 UM-BBD_reactionID:r0337|KEGG_REACTION:R05137|RHEA:27401|EC:5.99.1.4|MetaCyc:RXNN-386 Catalysis of the reaction: 2-hydroxychromene-2-carboxylate = (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate. (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate is also known as trans-o-hydroxybenzylidenepyruvate. GO:0018844 2-hydroxytetrahydrofuran isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018844 UM-BBD_reactionID:r0019|EC:5.3.99.- Catalysis of the reaction: 2-hydroxytetrahydrofuran = 4-hydroxybutyraldehyde. GO:0018841 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018841 GO:0018840 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018840 GO:0004209 obsolete caspase-6 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004209 caspase-6 activity OBSOLETE. (Was not defined before being made obsolete). GO:0004217 obsolete cathepsin L activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004217 cathepsin L activity|Aldrichina grahami cysteine proteinase OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Specificity close to that of papain. As compared to cathepsin B, cathepsin L exhibits higher activity towards protein substrates, but has little activity on Z-Arg-Arg-NHMec, and no peptidyl-dipeptidase activity. GO:0004216 obsolete cathepsin K activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004216 cathepsin O2 activity|cathepsin O activity|cathepsin K activity|cathepsin X activity OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Has a broad proteolytic activity. With small-molecule substrates and inhibitors, the major determinant of specificity is P2, which is preferably Leu, Met > Phe, and not Arg. GO:0004219 obsolete pyroglutamyl-peptidase I activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004219 MetaCyc:PYROGLUTAMYL-PEPTIDASE-I-RXN|EC:3.4.19.3 L-pyrrolidonecarboxylate peptidase activity|pyrrolidone carboxyl peptidase activity|pyroglutamate aminopeptidase activity|PYRase activity|pyrrolidone-carboxyl peptidase activity|L-pyroglutamyl peptide hydrolase activity|pyrrolidonyl peptidase activity|5-oxoprolyl-peptidase activity|pyroglutamyl-peptidase I activity|pyroglutamyl aminopeptidase activity|pyrrolidone-carboxylate peptidase activity|pyrrolidonecarboxylyl peptidase activity|pyroglutamidase activity OBSOLETE. Catalysis of the reaction: pyroglutamyl-peptide + H2O = pyroglutamate + peptide. GO:0004218 obsolete cathepsin S activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004218 cathepsin S activity OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Similar to cathepsin L, but with much less activity on the terminal bond of Z-Phe-Arg-NHMec, and more activity on the terminal bond of Z-Val-Val-Arg-Xaa compounds. GO:0004213 obsolete cathepsin B activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004213 cathepsin B1 activity|cathepsin B activity|cathepsin II OBSOLETE. Catalysis of the hydrolysis of peptide bonds with a broad specificity. Preferentially cleaves the terminal bond of -Arg-Arg-Xaa motifs in small molecule substrates (thus differing from cathepsin L). In addition to being an endopeptidase, shows peptidyl-dipeptidase activity, liberating C-terminal dipeptides. GO:0004212 obsolete lysosomal cysteine-type endopeptidase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004212 lysosomal cysteine-type endopeptidase OBSOLETE. (Was not defined before being made obsolete). GO:0004215 obsolete cathepsin H activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004215 cathepsin BA activity|cathepsin Ba|cathepsin H activity|benzoylarginine-naphthylamide (BANA) hydrolase activity|aleurain activity|cathepsin B3 activity|N-benzoylarginine-beta-naphthylamide hydrolase activity OBSOLETE. Catalysis of the hydrolysis of peptide bonds, acting as an aminopeptidase (notably, cleaving Arg-Xaa bonds) as well as an endopeptidase. GO:0004214 obsolete dipeptidyl-peptidase I activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004214 EC:3.4.14.1|MetaCyc:3.4.14.1-RXN dipeptide arylamidase I|DAP I|dipeptidyl transferase activity|dipeptidyl-peptidase I activity|cathepsin C activity|dipeptidyl aminopeptidase I activity|cathepsin J activity OBSOLETE. Catalysis of the release of an N-terminal dipeptide, Xaa-Xbb from Xaa-Xbb-Xcc, except when Xaa is Arg or Lys, or Xbb or Xcc is Pro. GO:0004211 obsolete caspase-9 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004211 caspase-9 activity OBSOLETE. (Was not defined before being made obsolete). GO:0004210 obsolete caspase-7 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0004210 caspase-7 activity OBSOLETE. (Was not defined before being made obsolete). GO:0018858 benzoate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018858 MetaCyc:BENZOATE--COA-LIGASE-RXN|EC:6.2.1.25|UM-BBD_reactionID:r0189|KEGG_REACTION:R01422|RHEA:10132 benzoate:CoA ligase (AMP-forming)|benzoyl CoA synthetase (AMP forming)|benzoyl-coenzyme A synthetase activity|benzoate-coenzyme A ligase activity Catalysis of the reaction: ATP + benzoate + CoA = AMP + benzoyl-CoA + diphosphate. GO:0018857 2,4-dichlorobenzoate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018857 UM-BBD_reactionID:r0137 Catalysis of the reaction: 2,4-dichlorobenzoate + ATP + CoASH = AMP + diphosphate + 2,4-dichlorobenzoyl-CoA. GO:0018859 4-hydroxybenzoate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018859 MetaCyc:4-HYDROXYBENZOATE--COA-LIGASE-RXN|EC:6.2.1.27|UM-BBD_reactionID:r0156|RHEA:23116|KEGG_REACTION:R01300 4-hydroxybenzoyl-CoA ligase activity|4-hydroxybenzoate:CoA ligase (AMP-forming)|4-hydroxybenzoyl coenzyme A synthetase activity|4-hydroxybenzoate-CoA synthetase activity|4-hydroxybenzoate-coenzyme A ligase (AMP-forming) Catalysis of the reaction: ATP + 4-hydroxybenzoate + CoA = AMP + diphosphate + 4-hydroxybenzoyl-CoA. GO:0018854 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018854 UM-BBD_reactionID:r0737 Catalysis of the reaction: (3R)-3-isopropenyl-6-oxoheptanoate + CoA-SH + ATP = H2O + ADP/AMP + mono/diphosphate + (3R)-3-isopropenyl-6-oxoheptanoyl-CoA. GO:0018853 obsolete perillyl-CoA synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018853 EC:6.2.1.-|UM-BBD_reactionID:r0731 perillyl-CoA synthetase activity OBSOLETE. Catalysis of the reaction: perillic acid + CoA-SH + ATP = H2O + ADP/AMP + mono/diphosphate + perillyl-CoA. GO:0018856 benzoyl acetate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018856 KEGG_REACTION:R05452|UM-BBD_reactionID:r0242|SABIO-RK:5058 Catalysis of the reaction: 3-oxo-3-phenylpropionate + CoA + ATP = AMP + diphosphate + benzoyl acetyl-CoA. GO:0018855 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018855 UM-BBD_reactionID:r0429|RHEA:33419|EC:6.2.1.38 Catalysis of the reaction: 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetate + ATP + CoA = AMP + diphosphate + 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA. GO:0018850 chloromuconate cycloisomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018850 UM-BBD_enzymeID:e0065|EC:5.5.1.7|RHEA:11032 muconate cycloisomerase II activity|2-chloro-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing) Catalysis of the reaction: 2-chloro-2,5-dihydro-5-oxofuran-2-acetate = 3-chloro-cis,cis-muconate. GO:0018852 dichloromuconate cycloisomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018852 MetaCyc:DICHLOROMUCONATE-CYCLOISOMERASE-RXN|UM-BBD_reactionID:r0277|EC:5.5.1.11|RHEA:17437 2,4-dichloro-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing) Catalysis of the reaction: 2,4-dichloro-2,5-dihydro-5-oxofuran-2-acetate = 2,4-dichloro-cis,cis-muconate. GO:0018851 alpha-pinene-oxide decyclase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018851 RHEA:16693|KEGG_REACTION:R04040|MetaCyc:ALPHA-PINENE-OXIDE-DECYCLASE-RXN|UM-BBD_reactionID:r0743|EC:5.5.1.10 alpha-pinene-oxide lyase (decyclizing)|alpha-pinene oxide lyase activity Catalysis of the reaction: alpha-pinene oxide = (Z)-2-methyl-5-isopropylhexa-2,5-dienal. CHEBI:19475 2-aminopentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19475 CHEBI:368997 N-benzyloxycarbonylglycinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_368997 CHEBI:138809 (3R)-3-hydroxy-4-oxobutanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138809 CHEBI:138808 CDP-4-dehydro-6-deoxy-alpha-D-glucose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138808 CHEBI:138807 ent-copal-8-ol diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138807 GO:0018829 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane dehydrochlorinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018829 UM-BBD_reactionID:r0513|EC:4.5.1.- DDD dehydrochlorinase activity Catalysis of the reaction: 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane = HCl + 1-chloro-2,2-bis(4-chlorophenyl)ethene. 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane is also known as DDD; 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU. GO:0018828 halohydrin hydrogen-halide-lyase A activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018828 UM-BBD_enzymeID:e0048 Catalysis of the elimination of HCl from a chloro- or bromopropanol, yielding an epoxypropane. GO:0018825 triethanolamine lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018825 UM-BBD_enzymeID:e0421 Catalysis of the reaction: triethanolamine = diethanolamine + acetaldehyde. CHEBI:138801 D-tagatopyranose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138801 GO:0018824 (hydroxyamino)benzene mutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018824 UM-BBD_reactionID:r0304|MetaCyc:5.4.4.1-RXN|RHEA:19245 hydroxylaminobenzene mutase activity|HAB mutase activity|hydroxylaminobenzene hydroxymutase activity|(hydroxyamino)benzene hydroxymutase activity Catalysis of the reaction: (hydroxyamino)benzene = 2-aminophenol. GO:0018827 1-chloro-2,2-bis(4-chlorophenyl)ethane dehydrochlorinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018827 UM-BBD_reactionID:r0515|EC:4.5.1.- DDMS dehydrochlorinase activity Catalysis of the reaction: 1-chloro-2,2-bis(4-chlorophenyl)ethane = HCl + unsym-bis(4-chlorophenyl)ethene. 1-chloro-2,2-bis(4-chlorophenyl)ethane is also known as DDMS; unsym-bis(4-chlorophenyl)ethene is also known as DDNU. GO:0018826 methionine gamma-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018826 UM-BBD_reactionID:r0432|RHEA:23800|EC:4.4.1.11|MetaCyc:METHIONINE-GAMMA-LYASE-RXN methioninase activity|L-methioninase activity|L-methionine methanethiol-lyase (deaminating; 2-oxobutanoate-forming)|methionine dethiomethylase activity|L-methionine methanethiol-lyase (deaminating)|L-methionine gamma-lyase activity|methionine lyase activity Catalysis of the reaction: L-methionine = methanethiol + NH3 + 2-oxobutanoate. GO:0018821 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018821 GO:0018820 cyanamide hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018820 MetaCyc:CYANAMIDE-HYDRATASE-RXN|UM-BBD_reactionID:r0668|KEGG_REACTION:R00778|EC:4.2.1.69|RHEA:23056 urea hydro-lyase activity|urea hydro-lyase (cyanamide-forming) Catalysis of the reaction: urea = cyanamide + H(2)O. GO:0018823 cyclohexa-1,5-dienecarbonyl-CoA hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018823 RHEA:21856|UM-BBD_reactionID:r0203|KEGG_REACTION:R05597|MetaCyc:4.2.1.100-RXN|EC:4.2.1.100 dienoyl-CoA hydratase activity|cyclohexa-1,5-dienecarbonyl-CoA hydro-lyase activity|6-hydroxycyclohex-1-enecarbonyl-CoA (cyclohexa-1,5-dienecarbonyl-CoA-forming)|cyclohexa-1,5-diene-1-carbonyl-CoA hydratase activity|cyclohexa-1,5-diene-1-carboxyl-CoA hydratase activity|cyclohex-1,5-diene-1-carbonyl-CoA hydratase activity Catalysis of the reaction: cyclohexa-1,5-diene-1-carbonyl-CoA + H(2)O = 6-hydroxycyclohex-1-enecarbonyl-CoA. CHEBI:138803 archaeosine 5'-phosphate zwitterionic residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138803 GO:0018822 nitrile hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018822 UM-BBD_enzymeID:e0067|EC:4.2.1.84|RHEA:12673|MetaCyc:NITRILE-HYDRATASE-RXN H-NHase activity|L-NHase activity|NHase activity|aliphatic-amide hydro-lyase (nitrile-forming)|acrylonitrile hydratase activity|3-cyanopyridine hydratase activity|nitrile hydro-lyase activity|aliphatic nitrile hydratase activity Catalysis of the reaction: an aliphatic amide = a nitrile + H2O. CHEBI:20476 4-sulfonatobenzoate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_20476 CHEBI:44423 hydroxyurea biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_44423 GO:0018839 cis-4-[2-(3-hydroxy)-thionaphthenyl]-2-oxo-3-butenoate isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018839 UM-BBD_reactionID:r0163|EC:5.2.1.- Catalysis of the reaction: cis-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate = trans-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate. GO:0018836 alkylmercury lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018836 RHEA:18777|MetaCyc:ALKYLMERCURY-LYASE-RXN|EC:4.99.1.2|UM-BBD_enzymeID:e0055 organomercurial lyase activity|alkylmercury mercuric-lyase activity|organomercury lyase activity|alkylmercury mercuric-lyase (alkane-forming) Catalysis of the reaction: R-Hg+ + H+ = R-H + Hg2+. GO:0018835 carbon phosphorus lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018835 EC:4.7.1.- Catalysis of the reaction: alkylphosphonic acid = R-CH3 + phosphate. Substrates include aminomethylphosphonic acid (AMPA) (forms methylamine), dimethylphosphinic acid (forms methylphosphonic acid), glyphosate (forms sarcosine) and methylphosphonic acid (forms phosphate). GO:0018838 mandelate racemase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018838 UM-BBD_reactionID:r0091|EC:5.1.2.2|MetaCyc:MANDELATE-RACEMASE-RXN|RHEA:13945 Catalysis of the reaction: (S)-mandelate = (R)-mandelate. GO:0018837 2-hydroxy-2H-benzo[h]chromene-2-carboxylate isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018837 UM-BBD_reactionID:r0502 Catalysis of the reaction: 2-hydroxy-2 H-benzo[h]chromene-2-carboxylate = cis -4-(1'-hydroxynaphth-2'-yl)-2-oxobut-3-enoate. GO:0018832 halohydrin hydrogen-halide-lyase B activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018832 UM-BBD_enzymeID:e0050 Catalysis of the elimination of HCl from a chloropropanol, yielding an epoxypropane. GO:0018831 5-chloro-1,2,4-trihydroxybenzene dechlorinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018831 EC:4.5.1.-|UM-BBD_reactionID:r0666 Catalysis of the reaction: 5-chloro-1,2,4-trihydroxybenzene = Cl- + H+ + 2-hydroxy-1,4-benzoquinone. GO:0018834 dichloromethane dehalogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018834 EC:4.5.1.3|RHEA:15397|MetaCyc:DICHLOROMETHANE-DEHALOGENASE-RXN|KEGG_REACTION:R00603|UM-BBD_reactionID:r0188 dichloromethane chloride-lyase (chloride-hydrolysing)|dichloromethane chloride-lyase (adding H2O; chloride-hydrolysing; formaldehyde-forming) Catalysis of the reaction: dichloromethane + H(2)O = 2 chloride + formaldehyde + 2 H(+). GO:0018833 DDT-dehydrochlorinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018833 RHEA:19217|EC:4.5.1.1|MetaCyc:DDT-DEHYDROCHLORINASE-RXN|UM-BBD_reactionID:r0439|KEGG_REACTION:R04522 DDT dehydrochlorinase activity|DDT-ase activity|DDTase activity|1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane chloride-lyase activity|DDT-as|1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane chloride-lyase [1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene-forming] Catalysis of the reaction: 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane = 1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene + chloride + H(+). CHEBI:20479 (5-oxo-2-sulfonato-2,5-dihydrofuran-2-yl)acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_20479 GO:0018830 gamma-hexachlorocyclohexane dehydrochlorinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018830 EC:4.5.1.-|UM-BBD_enzymeID:e0359 Catalysis of the reaction: gamma-hexachlorocyclohexane + HCl = 1,3(R),4(S),5(S),6(R)-pentachlorocyclohexene. SO:0000165 enhancer biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000165 http://en.wikipedia.org/wiki/Enhancer_(genetics) INSDC_qualifier:enhancer|INSDC_feature:regulatory A cis-acting sequence that increases the utilization of (some) eukaryotic promoters, and can function in either orientation and in any location (upstream or downstream) relative to the promoter. UBERON:0001309 internal iliac artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001309 hypogastric artery|arteria iliaca interna The internal iliac artery (formerly known as the hypogastric artery) is the main artery of the pelvis. [WP,unvetted]. UBERON:0001308 external iliac artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001308 arteria iliaca externa The external iliac artery is a large artery in the pelvic region that carries blood to the lower limb. The external iliac artery is a paired artery, meaning there is one on each side of the body: a right external iliac artery and left external iliac artery. The external iliac artery is accompanied by the external iliac vein, which is located posterior to the artery. [WP,unvetted]. CHEBI:73774 enterobacterial common antigen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73774 SO:0000167 promoter biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000167 http://en.wikipedia.org/wiki/Promoter INSDC_qualifier:promoter|promoter sequence|INSDC_feature:regulatory A regulatory_region composed of the TSS(s) and binding sites for TF_complexes of the core transcription machinery. A region (DNA) to which RNA polymerase binds, to begin transcription. CHEBI:73777 N-acetyl-D-mannosaminouronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73777 CHEBI:73776 N-acetyl-D-glucosaminyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73776 UBERON:0001305 ovarian follicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001305 follicle of ovary|ovary follicle|follicle of ovary viewed macroscopically|egg follicle|folliculi ovarici primarii|folliculi ovarici vesiculosi A spherical aggregation of cells in the ovary that contains a single oocyte[WP,modified]. CHEBI:73779 Gly-Pro zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73779 UBERON:0001304 germinal epithelium of ovary biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001304 ovary germinal epithelium|surface epithelium of ovary|ovarian surface epithelium|germinal epithelium (female)|epithelium superficiale (ovarium)|ovary surface epithelium|female coelomic epithelium layer of simple cuboidal cells covering surface of ovary[WP]. UBERON:0001307 capsule of ovary biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001307 ovary capsule|ovarian capsule A capsule that surrounds a female gonad. UBERON:0001306 cumulus oophorus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001306 cumulus ovaricus|discus proligerus|ovarian cumulus A cluster of cells that project into the cavity of the mature ovarian follicle. It is released with the embedded oocyte during ovulation. In order for fertilization to occur this layer must be penetrated by the spermatocyte. [WP,modified]. CHEBI:58133 3-(imidazol-5-yl)pyruvate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58133 CHEBI:58132 3-chloro-L-alanine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58132 CHEBI:58131 2-methylpropanoyl phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58131 CHEBI:58130 myo-inositol hexakisphosphate(12-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58130 UBERON:0001312 superior vesical artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001312 arteriae vesicales superiores|arteria vesicali superior|arteria vesicalis superior An artery that supplies blood to the upper urinary bladder. CHEBI:58139 3-hydroxy-cis,cis-muconate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58139 CHEBI:58138 N-caffeoylputrescinium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58138 CHEBI:73771 Ala-His biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73771 CHEBI:34162 16(R)-HETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_34162 CHEBI:73770 Ala-Leu biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73770 CHEBI:58137 3,4-dihydroxyphthalate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58137 UBERON:0001310 umbilical artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001310 a. umbilicalis The umbilical artery is a paired artery (with one for each half of the body) that is found in the abdominal and pelvic regions. In the fetus, it extends into the umbilical cord. [WP,unvetted]. CHEBI:58136 2,5-dioxopentanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58136 CHEBI:58135 2-(hydroxymethyl)-4-oxobutanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58135 CHEBI:73772 K antigen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73772 CHEBI:73786 Ala-Gly zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73786 CHEBI:73785 4-acetamido-4,6-dideoxy-D-galactosyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73785 CHEBI:73788 Ala-Gln biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73788 CHEBI:83103 N(6)-[(R)-S(8)-aminomethyldihydrolipoyl]-L-lysine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83103 CHEBI:58123 (2S)-2-hydroxy monocarboxylic acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58123 CHEBI:58122 N(6)-acetyl-N(6)-hydroxy-L-lysine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58122 CHEBI:83100 N(6)-[(R)-dihydrolipoyl]-L-lysine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83100 CHEBI:58121 D-ribulose 5-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58121 CHEBI:143816 alpha-D-glucosaminyl-(1->6)-(phosphatidyl)-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_143816 CHEBI:143815 N-acetyl-alpha-D-glucosaminyl-(1->6)-(phosphatidyl)-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_143815 CHEBI:143813 1-radyl,2-acyl-sn-glycero-3-phospho-(1D-myo-2-acyl-inositol)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_143813 UBERON:0001301 epididymis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001301 Nebenhoden@de the elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens UBERON:0001303 left uterine tube biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001303 left fallopian tube|left oviduct A fallopian tube that is part of a left side of organism [Automatically generated definition]. CHEBI:58129 cis-caffeate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58129 CHEBI:34172 16alpha-hydroxytestosterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_34172 UBERON:0001302 right uterine tube biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001302 right oviduct|right fallopian tube A fallopian tube that is part of a right side of organism [Automatically generated definition]. CHEBI:58128 N(5)-ethyl-L-glutamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58128 CHEBI:58127 GDP-D-glucose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58127 CHEBI:58126 porphobilinogen(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58126 CHEBI:73781 N-acetyl-D-mannosaminouronosyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73781 CHEBI:73784 Gly-Glu(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73784 CHEBI:58125 3-hydroxy-L-kynurenine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58125 CHEBI:73783 4-acetamido-4,6-dideoxy-D-galactose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73783 CHEBI:143819 C-terminal amino acid residue(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_143819 CHEBI:58124 isovitexin 2''-O-beta-D-glucoside(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58124 CHEBI:48796 iron-sulfur-molybdenum cluster biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48796 SO:0000188 intron biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000188 http://en.wikipedia.org/wiki/Intron INSDC_feature:intron A region of a primary transcript that is transcribed, but removed from within the transcript by splicing together the sequences (exons) on either side of it. CHEBI:58112 cetraxate zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58112 CHEBI:34145 12(R)-HPETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_34145 CHEBI:83111 N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83111 CHEBI:34144 12(R)-HETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_34144 CHEBI:58111 N(5)-acyl-L-ornithine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58111 CHEBI:58110 CDP-3,6-dideoxy-D-glucose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58110 CHEBI:34146 12(S)-HETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_34146 CHEBI:58119 N(4)-phosphonatoagmatine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58119 CHEBI:58118 L-rhamnonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58118 CHEBI:58117 (S)-2-acetamido-6-oxopimelate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58117 CHEBI:58116 5-methyl-5,6,7,8-tetrahydromethanopterin(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58116 CHEBI:58115 guanosine 5'-monophosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58115 CHEBI:73792 1-arachidonoyl-sn-glycerol 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73792 CHEBI:58114 2-carboxylato-cis,cis-muconate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58114 CHEBI:58113 L-2-ammoniohexano-6-lactam biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58113 SO:0000170 RNApol_II_promoter biolink:SequenceFeature go-plus http://purl.obolibrary.org/obo/SO_0000170 pol II promoter|RNApol II promoter|polymerase II promoter|RNA polymerase B promoter A DNA sequence in eukaryotic DNA to which RNA polymerase II binds, to begin transcription. CHEBI:58101 N(1)-acetylsperminium(3+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58101 UBERON:0015917 superficial lymph node biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015917 A lymph node that is located close to the surface. CHEBI:58100 N(6),N(6),N(6)-trimethyl-L-lysine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58100 CHEBI:34157 14,15-EET biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_34157 CHEBI:83120 N(6)-[(R)-S(8)-succinyldihydrolipoyl]-L-lysine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83120 UBERON:0015918 deep lymph node biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015918 A lymph node that is located deeper within the organism, further from the surface. CHEBI:34159 15-deoxy-Delta(12,14)-prostaglandin J2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_34159 CHEBI:58109 (2-chloro-5-oxo-2,5-dihydro-2-furyl)acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58109 CHEBI:58106 UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-N(6)-(L-alanyl)-L-lysyl-D-alanyl-D-alaninate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58106 CHEBI:58105 N(6)-[(indol-3-yl)acetyl]-L-lysine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58105 CHEBI:58104 nucleoside triphosphate(3-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58104 CHEBI:34151 12-oxo-ETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_34151 CHEBI:58103 5,6,7,8-tetrahydromethanopterin(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58103 CHEBI:34154 13(S)-HODE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_34154 CHEBI:58102 2-N,6-O-disulfonato-D-glucosamine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58102 CHEBI:48775 cadmium(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48775 UBERON:0001348 brown adipose tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001348 textus adiposus fuscus|textus adiposus fuscus|BAT|adipocytus multigutturalis|brown fat|multilocular adipose tissue A thermogenic form of adipose tissue that is composed of brown adipocytes[MP,modified] CHEBI:83139 long-chain fatty acyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83139 CHEBI:34127 11(R)-HPETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_34127 CHEBI:34126 11(R)-HETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_34126 UBERON:0001356 medial circumflex femoral artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001356 medial femoral circumflex artery|arteria circumflexa femoris medialis The medial circumflex femoral artery (internal circumflex artery, medial femoral circumflex artery) is an artery in the upper thigh that helps supply blood to the neck of the femur. [WP,unvetted]. UBERON:0001355 deep femoral artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001355 arteria profunda femoris|profunda femoris artery The profunda femoris artery (also known as the deep femoral artery, or the deep artery of the thigh) is a branch of the femoral artery that, as its name suggests, travels more deeply (posteriorly) than the rest of the femoral artery. [WP,unvetted]. UBERON:0001352 external acoustic meatus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001352 auditory canal|external auditory meatus|external auditory tube|ear canal|external acoustic tube|external auditory canal|auditory meatus A tube running from the outer ear to the middle ear. The human ear canal extends from the pinna to the eardrum and is about 26 mm in length and 7 mm in diameter. UBERON:0001353 anal region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001353 posterior|posterior end of organism The anus and surrounding regions. Encompasses both internal and external regions, where present CHEBI:48765 dimethylarsinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48765 UBERON:0001338 urethral gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001338 urethra gland (male or female)|urethral mucuous gland|urethra gland|gland of urethra Any of the numerous small mucous-secreting glands located in the wall of the male or female urethra that help protect the epithelium from the corrosive urine GO:0047504 (-)-menthol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047504 MetaCyc:--MENTHOL-DEHYDROGENASE-RXN|RHEA:13917|KEGG_REACTION:R02177|UM-BBD_reactionID:r1182|EC:1.1.1.207 (-)-menthol:NADP+ oxidoreductase activity|monoterpenoid dehydrogenase activity Catalysis of the reaction: (-)-menthol + NADP(+) = (2S,5R)-menthone + H(+) + NADPH. GO:0047503 (-)-borneol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047503 KEGG_REACTION:R02945|RHEA:22128|MetaCyc:--BORNEOL-DEHYDROGENASE-RXN|EC:1.1.1.227 (-)-borneol:NAD+ oxidoreductase activity Catalysis of the reaction: (-)-borneol + NAD(+) = (1S,4S)-camphor + H(+) + NADH. GO:0047502 (+)-sabinol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047502 KEGG_REACTION:R03745|RHEA:18329|EC:1.1.1.228|MetaCyc:+-SABINOL-DEHYDROGENASE-RXN (+)-cis-sabinol dehydrogenase activity|(+)-cis-sabinol:NAD+ oxidoreductase activity Catalysis of the reaction: (+)-cis-sabinol + NAD(+) = (1S,5S)-sabinone + H(+) + NADH. GO:0047501 (+)-neomenthol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047501 KEGG_REACTION:R02548|RHEA:23812|EC:1.1.1.208|MetaCyc:+-NEOMENTHOL-DEHYDROGENASE-RXN monoterpenoid dehydrogenase activity|(+)-neomenthol:NADP+ oxidoreductase activity Catalysis of the reaction: (+)-neomenthol + NADP(+) = (2S,5R)-menthone + H(+) + NADPH. GO:0047500 (+)-borneol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047500 EC:1.1.1.198|KEGG_REACTION:R02944|RHEA:17329|MetaCyc:+-BORNEOL-DEHYDROGENASE-RXN bicyclic monoterpenol dehydrogenase activity|(+)-borneol:NAD+ oxidoreductase activity Catalysis of the reaction: (+)-borneol + NAD(+) = (1R, 4R)-camphor + H(+) + NADH. CHEBI:83148 glycino(1-) group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83148 CHEBI:83147 15alpha-hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83147 CHEBI:83146 Daphnia tenebrosa metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83146 CHEBI:83145 carboxybiotinyl-L-lysine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83145 CHEBI:34133 11-oxotestosterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_34133 CHEBI:83144 biotinyl-L-lysine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83144 CHEBI:83143 N(6)-[(R)-S(8)-ammoniomethyldihydrolipoyl]-L-lysine(1+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83143 GO:0047509 (R)-dehydropantoate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047509 MetaCyc:R-DEHYDROPANTOATE-DEHYDROGENASE-RXN|EC:1.2.1.33|RHEA:19349|KEGG_REACTION:R03198 D-aldopantoate dehydrogenase activity|(R)-4-dehydropantoate:NAD+ 4-oxidoreductase activity|D-2-hydroxy-3,3-dimethyl-3-formylpropionate:diphosphopyridine nucleotide (DPN+) oxidoreductase activity Catalysis of the reaction: (R)-4-dehydropantoate + H(2)O + NAD(+) = (R)-3,3-dimethylmalate + 2 H(+) + NADH. CHEBI:83142 N(6)-[(R)-S(8)-isobutyryldihydrolipoyl]-L-lysine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83142 GO:0047508 (R)-2-methylmalate dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047508 EC:4.2.1.35|MetaCyc:R-2-METHYLMALATE-DEHYDRATASE-RXN|KEGG_REACTION:R03896|RHEA:22332 (R)-2-methylmalate hydro-lyase activity|citraconate hydratase activity|citraconase activity|(R)-2-methylmalate hydro-lyase (2-methylmaleate-forming)|(-)-citramalate hydro-lyase activity|citramalate hydro-lyase activity Catalysis of the reaction: (R)-citramalate = 2-methylmaleate + H(2)O. GO:0047507 (deoxy)nucleoside-phosphate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047507 RHEA:11216|MetaCyc:DEOXYNUCLEOSIDE-PHOSPHATE-KINASE-RXN|EC:2.7.4.13 deoxynucleoside-5'-monophosphate kinase activity|ATP:deoxynucleoside-phosphate phosphotransferase activity|deoxyribonucleoside monophosphokinase activity|deoxynucleoside monophosphate kinase activity Catalysis of the reaction: ATP + deoxynucleoside phosphate = ADP + deoxynucleoside diphosphate. GO:0047506 (deoxy)adenylate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047506 MetaCyc:DEOXYADENYLATE-KINASE-RXN|EC:2.7.4.11|RHEA:23100 ATP:(d)AMP phosphotransferase activity Catalysis of the reaction: ATP + dAMP = ADP + dADP. GO:0047505 (-)-menthol monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047505 EC:1.14.13.46|MetaCyc:--MENTHOL-MONOOXYGENASE-RXN|RHEA:11648|KEGG_REACTION:R02178 (-)-menthol,NADPH:oxygen oxidoreductase (8-hydroxylating)|l-menthol monooxygenase activity Catalysis of the reaction: (-)-menthol + H(+) + NADPH + O(2) = 1,4-menthane-3,8-diol + H(2)O + NADP(+). UBERON:0001344 epithelium of vagina biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001344 epithelial tissue of vagina|epithelium, vaginal|vagina epithelial tissue|vagina epithelium|vaginal epithelium The epithelial layer of the vagina. UBERON:0001347 white adipose tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001347 textus adiposus albus|unilocular adipose tissue|textus adiposus albus|adipocytus unigutturalis|white fat Connective tissue consisting of fat-storing cells and arranged in lobular groups or along minor blood vessels[MP,modified] CHEBI:34130 11,12-EET biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_34130 UBERON:0001343 seminiferous tubule of testis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001343 seminiferous cord|testis - seminiferous tubule|tubuli seminiferi|seminiferous tubule|tubuli seminiferi The tubules in the testes where spermatogenesis occurs. CHEBI:24786 iminodiacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24786 CHEBI:24785 iminodiacetate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24785 CHEBI:24783 imine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24783 CHEBI:24789 indanones biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24789 UBERON:0001328 lobe of prostate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001328 prostate gland lobe|prostatic lobe|lobe of prostate gland A portion of a prostate that forms a lobe. GO:0047515 1,3-beta-oligoglucan phosphorylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047515 EC:2.4.1.30|MetaCyc:13-BETA-OLIGOGLUCAN-PHOSPHORYLASE-RXN|RHEA:16041 beta-1,3-oligoglucan:orthophosphate glucosyltransferase II activity|beta-1,3-oligoglucan phosphorylase activity|1,3-beta-D-oligoglucan:phosphate alpha-D-glucosyltransferase activity Catalysis of the reaction: [oligomeric (1->3)-beta-D-glucosyl](n) + phosphate = [(1->3)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate. GO:0047514 1,3-beta-D-glucan phosphorylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047514 EC:2.4.1.97|MetaCyc:13-BETA-GLUCAN-PHOSPHORYLASE-RXN 1,3-beta-D-glucan:orthophosphate glucosyltransferase activity|1,3-beta-glucan phosphorylase activity|laminarin phosphoryltransferase activity|1,3-beta-D-glucan:phosphate alpha-D-glucosyltransferase activity|laminarin phosphorylase activity Catalysis of the reaction: [(1->3)-beta-D-glucosyl](n) + phosphate = [(1->3)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate; substrates include laminarin. GO:0047513 1,2-alpha-L-fucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047513 MetaCyc:12-ALPHA-L-FUCOSIDASE-RXN|RHEA:10816|EC:3.2.1.63 2-alpha-L-fucopyranosyl-beta-D-galactoside fucohydrolase activity|almond emulsin fucosidase activity|alpha-(1->2)-L-fucosidase activity|almond emulsin fucosidase II activity Catalysis of the reaction: H2O + methyl-2-alpha-L-fucopyranosyl-beta-D-galactoside = L-fucose + methyl beta-D-galactoside. GO:0047512 (S,S)-butanediol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047512 RHEA:12184|KEGG_REACTION:R03707|MetaCyc:SS-BUTANEDIOL-DEHYDROGENASE-RXN|EC:1.1.1.76 L-BDH|L-butanediol dehydrogenase activity|L(+)-2,3-butanediol dehydrogenase (L-acetoin forming)|(S,S)-butane-2,3-diol:NAD+ oxidoreductase activity Catalysis of the reaction: (S,S)-butane-2,3-diol + NAD(+) = acetoin + H(+) + NADH. GO:0047511 (S)-methylmalonyl-CoA hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047511 RHEA:17345|EC:3.1.2.17|KEGG_REACTION:R02764|MetaCyc:S-METHYLMALONYL-COA-HYDROLASE-RXN D-methylmalonyl-coenzyme A hydrolase activity Catalysis of the reaction: (S)-methylmalonyl-CoA + H(2)O = CoA + H(+) + methylmalonate. CHEBI:24782 imide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24782 GO:0047510 (S)-2-methylmalate dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047510 KEGG_REACTION:R03693|RHEA:13529|EC:4.2.1.34|MetaCyc:S-2-METHYLMALATE-DEHYDRATASE-RXN mesaconate mesaconase activity|(+)-citramalic hydro-lyase activity|(S)-2-methylmalate hydro-lyase (2-methylfumarate-forming)|(S)-2-methylmalate hydro-lyase activity|L-citramalate hydrolase activity|mesaconate hydratase activity|citramalate dehydratase activity|mesaconase activity|(+)-citramalate hydro-lyase activity Catalysis of the reaction: S-citramalate = H(2)O + mesaconate. CHEBI:24781 imidazolinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24781 CHEBI:24780 imidazoles biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24780 GO:0047519 quinate dehydrogenase (quinone) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047519 KEGG_REACTION:R01873|EC:1.1.5.8|RHEA:23672|MetaCyc:1.1.99.25-RXN quinate:quinone 3-oxidoreductase activity|NAD(P)-independent quinate dehydrogenase activity|quinate:pyrroloquinoline-quinone 5-oxidoreductase activity Catalysis of the reaction: (-)-quinate + pyrroloquinoline-quinone = (-)-3-dehydroquinate + pyrroloquinoline-quinol. GO:0047518 1-methyladenosine nucleosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047518 RHEA:12865|KEGG_REACTION:R03885|MetaCyc:1-METHYLADENOSINE-NUCLEOSIDASE-RXN|EC:3.2.2.13 1-methyladenosine ribohydrolase activity|1-methyladenosine hydrolase activity Catalysis of the reaction: 1-methyladenosine + H(2)O = 1-methyladenine + ribofuranose. GO:0047517 1,4-beta-D-xylan synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047517 RHEA:15289|MetaCyc:RXN-9104|EC:2.4.2.24 uridine diphosphoxylose-1,4-beta-xylan xylosyltransferase activity|xylan synthase activity|1,4-beta-xylan synthase activity|UDP-D-xylose:1,4-beta-D-xylan 4-beta-D-xylosyltransferase activity|xylan synthetase activity Catalysis of the reaction: UDP-D-xylose + [(1->4)-beta-D-xylan](n) = UDP + [(1->4)-beta-D-xylan](n+1). GO:0047516 1,3-propanediol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047516 RHEA:23188|EC:1.1.1.202|MetaCyc:13-PROPANEDIOL-DEHYDROGENASE-RXN 1,3-propanediol oxidoreductase activity|1,3-propanediol:NAD+ oxidoreductase activity|1,3-PD:NAD+ oxidoreductase activity|propane-1,3-diol:NAD+ 1-oxidoreductase activity|3-hydroxypropionaldehyde reductase activity Catalysis of the reaction: propane-1,3-diol + NAD+ = 3-hydroxypropanal + NADH + H+. UBERON:0001334 female urethra biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001334 urethra muliebris|urethra feminina A urethra that is part of a female reproductive system. UBERON:0001333 male urethra biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001333 A urethra that is part of a male reproductive system. UBERON:0001330 pampiniform plexus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001330 venous plexus of fascia of prostate gland|plexus of veins of fascia of prostate|venous plexus of fascia of prostate|pampiniform venous plexus|plexus venosus pampiniformis The pampiniform plexus is a network of many small veins found in the male spermatic cord. It is formed by the union of multiple spermatic veins from the back of the testis and tributaries from the epididymis. The veins of the plexus ascend along the cord in front of the ductus deferens. Below the subcutaneous inguinal ring they unite to form three or four veins, which pass along the inguinal canal, and, entering the abdomen through the abdominal inguinal ring, coalesce to form two veins. These again unite to form a single vein, the testicular vein, which opens on the right side into the inferior vena cava, at an acute angle, and on the left side into the left renal vein, at a right angle. The pampinoform plexus forms the chief mass of the cord. In addition to its function in venous return from the testes, the pampiniform plexus also plays a role in the temperature regulation of the testes. It acts as a heat exchanger, cooling blood in adjacent arteries. An abnormal enlargement of the pampiniform plexus is a medical condition called varicocele. [WP,unvetted]. UBERON:0001331 skin of penis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001331 zone of skin of penis|penis skin|penile skin|penis zone of skin A zone of skin that is part of a penis [Automatically generated definition]. CHEBI:24797 indole phytoalexin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24797 CHEBI:48742 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48742 CHEBI:48741 beta-phellandrene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48741 UBERON:0001319 vaginal vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001319 vein of vagina|vagina vein One the veins that drains the vaginal venous plexus, into the hypogastric veins. [WP,modified]. CHEBI:24796 indolylmethylglucosinolate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24796 UBERON:0001317 internal iliac vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001317 hypogastric vein|v. iliaca interna|v. hypogastrica A vein that begins near the upper part of the greater sciatic foramen, passes upward behind and slightly medial to the hypogastric artery and, at the brim of the pelvis, joins with the external iliac to form the common iliac vein. [WP,unvetted]. GO:0047526 2'-hydroxyisoflavone reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047526 MetaCyc:2-HYDROXYISOFLAVONE-REDUCTASE-RXN|EC:1.3.1.45|RHEA:22560 vestitone:NADP+ oxidoreductase activity|2',7-dihydroxy-4',5'-methylenedioxyisoflavone reductase activity|NADPH:2'-hydroxyisoflavone oxidoreductase activity|isoflavone reductase activity Catalysis of the reaction: vestitone + NADP+ = 2'-hydroxyformononetin + NADPH + H+. GO:0047525 2'-hydroxydaidzein reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047525 MetaCyc:RXN-4502|EC:1.3.1.51|RHEA:17145 2'-hydroxydihydrodaidzein:NADP(+) 2'-oxidoreductase activity|HDR activity|2'-hydroxydihydrodaidzein:NADP+ 2'-oxidoreductase activity|NADPH:2'-hydroxydaidzein oxidoreductase activity|2'-hydroxy-2,3-dihydrodaidzein:NADP+ 2'-oxidoreductase activity Catalysis of the reaction: 2'-hydroxydihydrodaidzein + NADP+ = 2'-hydroxydaidzein + NADPH + H+. GO:0047524 16-hydroxysteroid epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047524 EC:5.1.99.2|RHEA:15829|MetaCyc:16-HYDROXYSTEROID-EPIMERASE-RXN 16-hydroxysteroid 16-epimerase activity Catalysis of the reaction: 16-alpha-hydroxysteroid = 16-beta-hydroxysteroid. GO:0047523 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0047523 GO:0047522 15-oxoprostaglandin 13-oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047522 EC:1.3.1.48|KEGG_REACTION:R04557|KEGG_REACTION:R04556|MetaCyc:15-OXOPROSTAGLANDIN-13-REDUCTASE-RXN (5Z)-(15S)-11alpha-hydroxy-9,15-dioxoprostanoate:NAD(P)+ delta13-oxidoreductase activity Catalysis of the reaction: (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprostanoate + NAD(P)+ -> (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprosta-13-enoate + NAD(P)H + H+. CHEBI:24793 indoledione biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24793 GO:0047521 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047521 RHEA:21424|MetaCyc:12-BETA-HYDROXYSTEROID-DEHYDROGENASE-RXN|KEGG_REACTION:R03495|EC:1.1.1.238 12beta-hydroxysteroid:NADP+ 12-oxidoreductase activity|12beta-hydroxysteroid dehydrogenase activity|12beta-hydroxy steroid (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity|12-beta-hydroxysteroid dehydrogenase activity Catalysis of the reaction: 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate + NADP(+) = 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + H(+) + NADPH. GO:0047520 11-cis-retinyl-palmitate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047520 EC:3.1.1.63|KEGG_REACTION:R03049|MetaCyc:11-CIS-RETINYL-PALMITATE-HYDROLASE-RXN|Reactome:R-HSA-2465941|RHEA:19697 11-cis-retinol palmitate esterase activity|11-cis-retinyl-palmitate acylhydrolase activity|RPH Catalysis of the reaction: 11-cis-retinyl palmitate + H(2)O = 11-cis-retinol + H(+) + palmitate. CHEBI:83169 N-acyl homoserine lactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83169 CHEBI:34116 (9Z)-1-O-octadec-9-enyl glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_34116 CHEBI:34115 1-O-hexadecyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_34115 GO:0047529 2,3-dimethylmalate lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047529 EC:4.1.3.32|KEGG_REACTION:R01355|MetaCyc:23-DIMETHYLMALATE-LYASE-RXN|RHEA:10472 (2R,3S)-2,3-dimethylmalate pyruvate-lyase (propanoate-forming)|(2R,3S)-2,3-dimethylmalate pyruvate-lyase activity|2,3-dimethylmalate pyruvate-lyase activity Catalysis of the reaction: (2R,3S)-2,3-dimethylmalate = propanoate + pyruvate. GO:0047528 2,3-dihydroxyindole 2,3-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047528 EC:1.13.11.23|MetaCyc:23-DIHYDROXYINDOLE-23-DIOXYGENASE-RXN|KEGG_REACTION:R00983|RHEA:19445 2,3-dihydroxyindole:oxygen 2,3-oxidoreductase (decyclizing) activity Catalysis of the reaction: 2,3-dihydroxyindole + O(2) = anthranilate + CO(2) + H(+). CHEBI:34117 batilol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_34117 GO:0047527 2,3-dihydroxybenzoate-serine ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047527 EC:6.3.2.14|MetaCyc:23-DIHYDROXYBENZOATE--SERINE-LIGASE-RXN|RHEA:30571 2,3-dihydroxybenzoate:L-serine ligase activity|N-(2,3-dihydroxybenzoyl)-serine synthetase activity|2,3-dihydroxybenzoylserine synthetase activity Catalysis of the reaction: ATP + 2,3-dihydroxybenzoate + L-serine = products of ATP breakdown + N-(2,3-dihydroxybenzoyl)-L-serine. UBERON:0001325 muscle of pelvis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001325 pelvis muscle organ|pelvic muscle|muscle organ of pelvis|pelvis muscle Muscle (organ) which is a part of the pelvis. Examples: levator ani, CHEBI:143890 2-ammonioethyl (2R)-2,3-dihydroxypropyl phosphate zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_143890 CHEBI:73702 wax biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73702 CHEBI:73706 bromosuccinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73706 CHEBI:73709 (S)-2-hydroxybutyrate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73709 CHEBI:73712 bromosuccinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73712 CHEBI:58199 L-homocysteine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58199 CHEBI:58196 (3R)-3-hydroxy-L-aspartate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58196 CHEBI:58195 S-(5-deoxy-D-ribos-5-yl)-L-homocysteine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58195 CHEBI:58194 biochanin A(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58194 CHEBI:58193 3alpha(S)-strictosidinium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58193 CHEBI:73722 hexadecanedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73722 CHEBI:73723 N-oleoylglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73723 CHEBI:58192 quercitrin-7-olate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58192 CHEBI:58191 1-alkyl-2-acetyl-sn-glycerol 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58191 CHEBI:58190 O-phosphonatoethanaminium(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58190 CHEBI:58189 GDP(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58189 CHEBI:58188 UDP-N-acetyl-D-galactosamine 4-sulfate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58188 CHEBI:58187 alginate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58187 CHEBI:58186 1-phosphonato-alpha-D-galacturonate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58186 CHEBI:58185 2-carboxylato-D-arabinitol 1-phosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58185 CHEBI:58184 L-tyrosiniumyl-L-arginine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58184 CHEBI:58183 6-amino-2-oxohexanoic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58183 CHEBI:143878 N-acetyl-D-phenylalaninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_143878 CHEBI:143877 N-acetyl-L-tryptophanate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_143877 CHEBI:58182 (S)-6-hydroxynicotinium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58182 CHEBI:73731 (11Z,14Z)-icosadienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73731 CHEBI:73730 PPARbeta/delta agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73730 CHEBI:58181 trans-beta-D-glucosyl-2-hydroxycinnamate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58181 CHEBI:58180 L-arogenate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58180 CHEBI:58178 1-phosphatidyl-1D-myo-inositol 4-phosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58178 CHEBI:58177 testolate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58177 CHEBI:58176 phenylthioacetohydroximate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58176 CHEBI:58175 N-methyl-L-alanine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58175 CHEBI:58174 but-1-ene-1,2,4-tricarboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58174 CHEBI:58173 L-gamma-glutamyl-L-cysteinate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58173 CHEBI:58172 dTDP-D-fucose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58172 CHEBI:58171 7,8-dihydroxykynurenate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58171 CHEBI:58179 all-trans-hexaprenyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58179 CHEBI:73743 2-(3-amino-3-carboxypropyl)-L-histidine zwitterion residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73743 CHEBI:73745 2-[3-carboxylato-3-(dimethylammonio)propyl]-L-histidine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73745 CHEBI:73747 uridine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73747 CHEBI:58170 psychosine sulfate zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58170 CHEBI:58166 CDP-4-dehydro-6-deoxy-D-glucose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58166 CHEBI:58165 3',5'-cyclic AMP(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58165 CHEBI:58164 (S)-atropinium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58164 CHEBI:58163 homocystine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58163 CHEBI:58161 L-cystathionine dizwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58161 CHEBI:58169 2-(alpha-D-galactosyl)-sn-glycerol 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58169 CHEBI:58168 1-O-acyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58168 CHEBI:73754 thiosugar biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73754 CHEBI:73757 Ala-Gly biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73757 CHEBI:58156 N-adenylylanthranilate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58156 CHEBI:58155 N-methyltyraminium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58155 CHEBI:58154 N-(2,3-dihydroxybenzoyl)-L-serinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58154 CHEBI:58153 UDP-L-rhamnose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58153 CHEBI:58152 cis-4-coumarate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58152 CHEBI:58151 methanofuranate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58151 CHEBI:58150 3-D-glucuronosyl-N(2),6-disulfonato-beta-D-glucosamine(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58150 CHEBI:58159 uracil-5-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58159 CHEBI:58158 aminomalonate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58158 CHEBI:58157 2-O-caffeoylglucarate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58157 CHEBI:73764 2-[3-carboxy-3-(dimethylamino)propyl]-L-histidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73764 CHEBI:73763 2-[3-carboxylato-3-(dimethylammonio)propyl]-L-histidine dizwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73763 CHEBI:58145 agmatinium(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58145 CHEBI:58144 (R)-reticulinium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58144 CHEBI:58143 5-dehydro-D-gluconate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58143 CHEBI:58142 4-carboxy-2-hydroxy-cis,cis-muconate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58142 CHEBI:58141 P(1),P(4)-bis(5'-adenosyl) tetraphosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58141 CHEBI:58140 tetrahydropteroyltri-L-glutamate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58140 CHEBI:58149 3-hydroxyphenylacetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58149 CHEBI:58148 L-homocitrulline zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58148 CHEBI:58147 4-(2-aminophenyl)-2,4-dioxobutanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58147 CHEBI:73762 Ala-Thr biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73762 CHEBI:58146 (R)-5-phosphonatomevalonate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58146 GO:0072452 response to G2 transition size control checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072452 G2/M transition size control checkpoint effector process|response to G2/M transition size control checkpoint signaling|response to mitotic cell cycle G2/M transition size control checkpoint signaling|response to signal involved in G2/M transition size control checkpoint A process that occurs in response to signals generated as a result of G2/M transition size control checkpoint signaling. GO:0047496 vesicle transport along microtubule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0047496 microtubule-based vesicle localization The directed movement of a vesicle along a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination. GO:0072451 detection of stimulus involved in G2 cell size control checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072451 G2/M transition size control checkpoint sensor mechanism|G2/M transition size control checkpoint sensor process|detection of stimulus involved in G2/M transition size control checkpoint|detection of stimulus involved in mitotic cell cycle G2/M transition size control checkpoint|sensing involved in G2/M transition size control checkpoint The series of events in which information about cell size is received and converted into a molecular signal, contributing to a G2/M transition size control checkpoint. GO:0047495 membrane-oligosaccharide glycerophosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047495 EC:2.7.8.21|MetaCyc:2.7.8.21-RXN membrane-derived-oligosaccharide-6-(glycerophospho)-D-glucose:membrane-derived-oligosaccharide-D-glucose glycerophosphotransferase activity|periplasmic phosphoglycerotransferase activity|phosphoglycerol cyclase activity Catalysis of the transfer of a glycerophospho group from one membrane-derived oligosaccharide to another. GO:0072450 signal transduction involved in G1 cell size control checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072450 signal transduction involved in mitotic cell cycle G1/S transition size control checkpoint A signal transduction process that contributes to a cell size control checkpoint during the G1/S transition of mitosis. GO:0047494 serine-phosphoethanolamine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047494 RHEA:22656|EC:2.7.8.4|MetaCyc:SERINE-PHOSPHOETHANOLAMINE-SYNTHASE-RXN|KEGG_REACTION:R02563 CDP-ethanolamine:L-serine ethanolamine phosphotransferase activity|serine-phosphinico-ethanolamine synthase activity|serinephosphoethanolamine synthase activity|serine ethanolamine phosphodiester synthase activity|serine ethanolamine phosphate synthetase activity|serine ethanolaminephosphotransferase activity Catalysis of the reaction: L-serine + CDP-ethanolamine = L-serine-phosphoethanolamine + CMP + H(+). GO:0047493 ceramide cholinephosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047493 RHEA:16273|MetaCyc:CERAMIDE-CHOLINEPHOSPHOTRANSFERASE-RXN|EC:2.7.8.3|KEGG_REACTION:R01891 phosphorylcholine-ceramide transferase activity|CDP-choline:N-acylsphingosine cholinephosphotransferase activity Catalysis of the reaction: CDP-choline + ceramide = CMP + H(+) + sphingomyelin. GO:0047492 xanthan lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047492 MetaCyc:4.2.2.12-RXN|EC:4.2.2.12 Catalysis of the reaction: xanthan = oligosaccharide with 4-deoxy-alpha-L-threo-hex-4-enuronosyl end + pyruvylate mannose. This reaction is the eliminative cleavage of the terminal beta-D-mannosyl-beta-D-1,4-glucuronosyl linkage of the side-chain of the polysaccharide xanthan, leaving a 4-deoxy-alpha-L-threo-hex-4-enuronosyl group at the terminus of the side-chain. GO:0047491 poly(alpha-L-guluronate) lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047491 MetaCyc:4.2.2.11-RXN|EC:4.2.2.11 L-guluronan lyase activity|alginase II activity|poly(alpha-L-1,4-guluronide) exo-lyase activity|poly-alpha-L-guluronate lyase activity|polyguluronate-specific alginate lyase activity|guluronate lyase activity|L-guluronate lyase activity Catalysis of the reaction: polysaccharides containing a terminal alpha-L-guluronate group = oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enuronosyl end. This reaction is the eliminative cleavage of polysaccharides containing a terminal a-L-guluronate group, to give oligopolysaccharides with 4-deoxy-a-L-erythro-hex-4-enuronosyl groups at their nonreducing ends. GO:0047490 pectin lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047490 MetaCyc:4.2.2.10-RXN|EC:4.2.2.10 endo-pectin lyase activity|PNL activity|pectin trans-eliminase activity|pectin methyltranseliminase activity|polymethylgalacturonic transeliminase activity|PL activity|pectolyase activity|(1->4)-6-O-methyl-alpha-D-galacturonan lyase activity|PMGL activity Catalysis of the reaction: a pectin = an oligosaccharide with 4-deoxy-6-O-methyl-alpha-D-galact-4-enuronate end + a pectin. This reaction is the eliminative cleavage of (1->4)-alpha-D-galacturonan methyl ester to give oligosaccharides with 4-deoxy-6-O-methyl-alpha-D-galact-4-enuronosyl groups at their nonreducing ends. GO:0047499 calcium-independent phospholipase A2 activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0047499 Reactome:R-HSA-8952251 calcium-independent cytosolic phospholipase A2 activity Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. This reaction does not require Ca2+. GO:0047498 calcium-dependent phospholipase A2 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047498 Reactome:R-HSA-111883 calcium-dependent cytosolic phospholipase A2 activity|calcium-dependent secreted phospholipase A2 activity Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. This reaction requires Ca2+. GO:0047497 mitochondrion transport along microtubule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0047497 mitochondrial migration along microtubule|mitochondrial transport along microtubule The directed movement of a mitochondrion along a microtubule, mediated by motor proteins. GO:0072459 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072459 GO:0072458 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072458 GO:0072457 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072457 GO:0072456 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072456 GO:0072455 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072455 GO:0072454 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072454 GO:0072453 signal transduction involved in G2 cell size control checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072453 signal transduction involved in mitotic cell cycle G2/M transition size control checkpoint|signal transduction involved in G2/M transition size control checkpoint A signal transduction process that contributes to a cell size control checkpoint during the G2/M transition of mitosis. GO:0072441 response to meiotic DNA replication checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072441 response to signal involved in meiotic DNA replication checkpoint|meiotic DNA replication checkpoint effector process A process that occurs in response to signals generated as a result of meiotic DNA replication checkpoint signaling. GO:0072440 signal transduction involved in meiotic DNA replication checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072440 A signal transduction process that contributes to a meiotic DNA replication checkpoint. GO:0072449 response to G1 cell size control checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072449 mitotic cell cycle G1/S transition size control checkpoint effector process|response to signal involved in mitotic cell cycle G1/S transition size control checkpoint A process that occurs in response to signals generated as a result of mitotic cell cycle G1/S transition size control checkpoint signaling. GO:0072448 detection of stimulus involved in G1 cell size control checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072448 mitotic cell cycle G1/S transition size control checkpoint sensor mechanism|mitotic cell cycle G1/S transition size control checkpoint sensor process|detection of stimulus involved in mitotic cell cycle G1/S transition size control checkpoint|sensing involved in mitotic cell cycle G1/S transition size control checkpoint The series of events in which information about cell size is received and converted into a molecular signal, contributing to a mitotic cell cycle G1/S transition size control checkpoint. GO:0072447 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072447 GO:0072446 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072446 GO:0072445 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072445 GO:0072444 response to mitotic DNA replication checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072444 response to signal involved in S-M checkpoint|response to signal involved in mitotic DNA replication checkpoint|response to S-M checkpoint signaling|mitotic DNA replication checkpoint effector process|S-M checkpoint effector process A process that occurs in response to signals generated as a result of mitotic DNA replication checkpoint signaling. GO:0072443 signal transduction involved in mitotic DNA replication checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072443 signal transduction involved in mitotic G2/M transition decatenation checkpoint|signal transduction involved in S-M checkpoint A signal transduction process that contributes to a mitotic DNA replication checkpoint. GO:0072442 detection of stimulus involved in mitotic DNA replication checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072442 sensing involved in S-M checkpoint|mitotic DNA replication checkpoint sensor mechanism|sensing involved in mitotic DNA replication checkpoint|S-M checkpoint sensor mechanism|mitotic DNA replication checkpoint sensor process|S-M checkpoint sensor process|detection of stimulus involved in S-M checkpoint The series of events in which information about whether DNA replication is complete is received and converted into a molecular signal, contributing to a mitotic DNA replication checkpoint. GO:0072474 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072474 GO:0072473 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072473 GO:0072472 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072472 GO:0072471 signal transduction involved in cell size control checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072471 A signal transduction process that contributes to a cell size control checkpoint during mitosis. GO:0072470 response to cell size control checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072470 response to mitotic cell cycle cell size control checkpoint signaling|response to signal involved in cell size control checkpoint|cell size control checkpoint effector process A process that occurs in response to signals generated as a result of cell size control checkpoint signaling. GO:0072479 response to mitotic cell cycle spindle assembly checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072479 mitotic cell cycle spindle assembly checkpoint effector process|response to Dma1-dependent checkpoint signalling|response to signal involved in mitotic cell cycle spindle assembly checkpoint|response to Dma1-dependent checkpoint signaling A process that occurs in response to signals generated as a result of mitotic cell cycle spindle assembly checkpoint signaling. GO:0072478 detection of stimulus involved in mitotic spindle assembly checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072478 mitotic cell cycle spindle assembly checkpoint sensor process|detection of stimulus involved in SAC-independent checkpoint|stimulus detection involved in DMA1-dependent checkpoint|perception of stimulus involved in DMA1-dependent checkpoint|stimulus sensing involved in SAC-independent checkpoint|perception of stimulus involved in SAC-independent checkpoint|stimulus sensing involved in DMA1-dependent checkpoint|detection of stimulus involved in mitotic cell cycle spindle assembly checkpoint|detection of stimulus involved in Dma1-dependent checkpoint|sensing involved in mitotic cell cycle spindle assembly checkpoint|mitotic cell cycle spindle assembly checkpoint sensor mechanism|stimulus detection involved in SAC-independent checkpoint The series of events in which information about whether the spindle is correctly assembled, and chromosomes are attached to the spindle, is received and converted into a molecular signal, contributing to a mitotic cell cycle spindle assembly checkpoint. GO:0072477 signal transduction involved in mitotic spindle checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072477 signal transduction involved in mitotic cell cycle spindle checkpoint A signal transduction process that contributes to a mitotic cell cycle spindle checkpoint. GO:0072476 response to mitotic spindle checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072476 response to mitotic cell cycle spindle checkpoint signaling|response to signal involved in mitotic cell cycle spindle checkpoint|mitotic cell cycle spindle checkpoint effector process A process that occurs in response to signals generated as a result of mitotic cell cycle spindle checkpoint signaling. GO:0072475 detection of stimulus involved in mitotic spindle checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072475 mitotic cell cycle spindle checkpoint sensor mechanism|mitotic cell cycle spindle checkpoint sensor process|detection of stimulus involved in mitotic cell cycle spindle checkpoint|sensing involved in mitotic cell cycle spindle checkpoint The series of events in which information about whether the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle, is received and converted into a molecular signal, contributing to a mitotic cell cycle spindle checkpoint. GO:0072463 detection of stimulus involved in meiotic spindle assembly checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072463 meiotic spindle assembly checkpoint sensor mechanism|meiotic spindle assembly checkpoint sensor process|sensing involved in meiotic spindle assembly checkpoint The series of events in which information about whether spindle is correctly assembled and chromosomes are attached to the spindle is received and converted into a molecular signal, contributing to a meiotic spindle assembly checkpoint. GO:0072462 signal transduction involved in meiotic recombination checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072462 A signal transduction process that contributes to a meiotic recombination checkpoint. GO:0072461 response to meiotic recombination checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072461 response to signal involved in meiotic recombination checkpoint|meiotic recombination checkpoint effector process A process that occurs in response to signals generated as a result of meiotic recombination checkpoint signaling. GO:0072460 detection of stimulus involved in meiotic recombination checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072460 meiotic recombination checkpoint sensor mechanism|sensing involved in meiotic recombination checkpoint|meiotic recombination checkpoint sensor process The series of events in which information about whether recombination is complete is received and converted into a molecular signal, contributing to a meiotic recombination checkpoint. GO:0072469 detection of stimulus involved in cell size control checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072469 cell size control checkpoint sensor mechanism|detection of stimulus involved in mitotic cell cycle cell size control checkpoint|sensing involved in cell size control checkpoint|cell size control checkpoint sensor process The series of events in which information about cell size is received and converted into a molecular signal, contributing to a cell size control checkpoint. GO:0072468 obsolete signal transduction involved in cell shape checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072468 OBSOLETE. A signal transduction process that contributes to a cell shape checkpoint. GO:0072467 obsolete response to cell shape checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072467 cell shape checkpoint effector process|response to signal involved in cell shape checkpoint OBSOLETE. A process that occurs in response to signals generated as a result of cell shape checkpoint signaling. GO:0072466 obsolete detection of stimulus involved in cell shape checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072466 cell shape checkpoint sensor process|sensing involved in cell shape checkpoint|cell shape checkpoint sensor mechanism OBSOLETE. The series of events in which information about aspects of cell polarity control is received and converted into a molecular signal, contributing to a cell shape checkpoint. GO:0072465 signal transduction involved in meiotic spindle assembly checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072465 A signal transduction process that contributes to a meiotic spindle assembly checkpoint. GO:0072464 response to meiotic spindle assembly checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072464 response to signal involved in meiotic spindle assembly checkpoint|meiotic spindle assembly checkpoint effector process A process that occurs in response to signals generated as a result of meiotic spindle assembly checkpoint signaling. GO:0072496 Pup transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0072496 Pup conjugating enzyme activity Catalysis of the transfer of Pup from one protein to another via the reaction X-Pup + Y --> Y-Pup + X, where both X-Pup and Y-Pup are covalent linkages. GO:0072495 host cell Cajal body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0072495 coiled body of host|host cell coiled body A class of nuclear body in the eukaryotic host cell, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA. The host is the larger of the organisms involved in a symbiotic interaction. GO:0072494 host multivesicular body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0072494 host cell multivesicular body A late endosome in which regions of the limiting host cell endosomal membrane invaginate to form internal vesicles; host membrane proteins that enter the internal vesicles are sequestered from the host cytoplasm. GO:0072493 host cell endosome lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0072493 host endosome lumen The volume enclosed by the membranes of the host cell endosome. GO:0072492 host cell mitochondrial intermembrane space biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0072492 The region between the inner and outer lipid bilayers of the host cell mitochondrial envelope. GO:0072491 toluene-containing compound catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072491 toluene-containing compound degradation|toluene-containing compound breakdown|toluene-containing compound catabolism|toluene and derivative catabolic process The chemical reactions and pathways resulting in the breakdown of toluene, methylbenzene (formula C7H8), or any of its derivatives. GO:0072490 toluene-containing compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072490 toluene-containing compound metabolism|toluene and derivative metabolic process The chemical reactions and pathways involving toluene, methylbenzene (formula C7H8), or any of its derivatives. GO:0072499 photoreceptor cell axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072499 photoreceptor cell axon pathfinding The chemotaxis process that directs the migration of a photoreceptor cell axon growth cone to its target in the optic lobe in response to a combination of attractive and repulsive cues. GO:0072498 embryonic skeletal joint development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072498 The process, occurring during the embryonic phase, whose specific outcome is the progression of the skeletal joints over time, from formation to mature structure. GO:0072497 mesenchymal stem cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072497 The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells. GO:0072485 response to spindle assembly checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072485 response to signal involved in spindle assembly checkpoint|spindle assembly checkpoint effector process A process that occurs in response to signals generated as a result of spindle assembly checkpoint signaling. GO:0072484 detection of stimulus involved in spindle assembly checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072484 sensing involved in spindle assembly checkpoint|spindle assembly checkpoint sensor mechanism|spindle assembly checkpoint sensor process The series of events in which information about spindle assembly is received and converted into a molecular signal, contributing to a spindle assembly checkpoint. GO:0072483 signal transduction involved in mitotic cell cycle spindle orientation checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072483 A signal transduction process that contributes to a mitotic cell cycle spindle orientation checkpoint. GO:0072482 response to mitotic cell cycle spindle orientation checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072482 response to signal involved in mitotic cell cycle spindle orientation checkpoint|mitotic cell cycle spindle orientation checkpoint effector process A process that occurs in response to signals generated as a result of mitotic cell cycle spindle orientation checkpoint signaling. GO:0072481 detection of stimulus involved in mitotic spindle orientation checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072481 mitotic cell cycle spindle orientation checkpoint sensor mechanism|mitotic cell cycle spindle orientation checkpoint sensor process|detection of stimulus involved in mitotic cell cycle spindle orientation checkpoint|sensing involved in mitotic cell cycle spindle orientation checkpoint The series of events in which information about whether the spindle is correctly oriented is received and converted into a molecular signal, contributing to a mitotic cell cycle spindle orientation checkpoint. GO:0072480 mitotic spindle assembly checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072480 signal transduction involved in mitotic cell cycle spindle assembly checkpoint|signal transduction involved in Dma1-dependent checkpoint|signaling cascade involved in SAC-independent checkpoint|signaling pathway involved in SAC-independent checkpoint|signalling pathway involved in Dma1-dependent checkpoint|signalling cascade involved in SAC-independent checkpoint|signalling pathway involved in SAC-independent checkpoint|signaling pathway involved in Dma1-dependent checkpoint|mitotic spindle assembly checkpoint signalling|signal transduction involved in SAC-independent checkpoint|signal transduction involved in mitotic spindle assembly checkpoint|signalling cascade involved in Dma1-dependent checkpoint|signaling cascade involved in Dma1-dependent checkpoint A signal transduction process that contributes to a mitotic cell cycle spindle assembly checkpoint. GO:0072489 methylammonium transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072489 methylammonium membrane transport The process in which methylammonium is transported across a membrane. GO:0072488 ammonium transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072488 ammonium membrane transport The process in which ammonium is transported across a membrane. Ammonium is the cation NH4+. GO:0072487 MSL complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0072487 A histone acetyltransferase complex that catalyzes the acetylation of a histone H4 lysine residue at position 16. In human, it contains the catalytic subunit MOF, and MSL1, MSL2 and MSL3. GO:0072486 signal transduction involved in spindle assembly checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072486 A signal transduction process that contributes to a spindle assembly checkpoint. CHEBI:24768 iduronates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24768 CHEBI:24766 iditol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24766 CHEBI:24765 idaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24765 GO:0047416 arylalkyl acylamidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047416 EC:3.5.1.76|RHEA:10352|MetaCyc:3.5.1.76-RXN aralkyl acylamidase activity|N-acetylarylalkylamine amidohydrolase activity Catalysis of the reaction: H2O + N-acetylarylalkylamine = acetate + arylalkylamine. OBO:GOCHE_39317 substance with growth regulator role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_39317 GO:0047415 D-benzoylarginine-4-nitroanilide amidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047415 KEGG_REACTION:R04113|RHEA:14421|EC:3.5.1.72|MetaCyc:3.5.1.72-RXN D-BAPA-ase activity|N-benzoyl-D-arginine-4-nitroanilide amidohydrolase activity|benzoyl-D-arginine arylamidase activity Catalysis of the reaction: N(2)-benzoyl-D-arginine-4-nitroanilide + H(2)O = 4-nitroaniline + N(2)-benzoyl-D-arginine + H(+). CHEBI:10119 ziprasidone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_10119 GO:0047414 2-(hydroxymethyl)-3-(acetamidomethylene)succinate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047414 EC:3.5.1.66|Wikipedia:2-(hydroxymethyl)-3-(acetamidomethylene)succinate_amidohydrolase_(deaminating,_decarboxylating)|RHEA:17677|KEGG_REACTION:R04397|MetaCyc:3.5.1.66-RXN alpha-hydroxymethyl-alpha'-(N-acetylaminomethylene)succinic acid hydrolase activity|2-(hydroxymethyl)-3-(acetamidomethylene)succinate amidohydrolase (deaminating, decarboxylating)|compound B hydrolase activity Catalysis of the reaction: (2Z)-2-(acetamidomethylene)-3-(hydroxymethyl)succinate + 2 H(2)O + H(+) = 2-(hydroxymethyl)-4-oxobutanoate + acetate + CO(2) + NH(4)(+). GO:0047413 N(alpha)-benzyloxycarbonylleucine hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047413 EC:3.5.1.64|RHEA:18901|KEGG_REACTION:R02552|MetaCyc:3.5.1.64-RXN nalpha-benzyloxycarbonylleucine hydrolase activity|benzyloxycarbonylleucine hydrolase activity|alpha-N-benzyloxycarbonyl-L-leucine urethanehydrolase activity|nalpha-benzyloxycarbonyl amino acid urethane hydrolase IV|nalpha-benzyloxycarbonyl-L-leucine urethanehydrolase activity Catalysis of the reaction: N-benzyloxycarbonyl-L-leucine + H(2)O + H(+) = L-leucine + benzyl alcohol + CO(2). GO:0047412 N-(long-chain-acyl)ethanolamine deacylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047412 RHEA:17505|EC:3.5.1.60|MetaCyc:3.5.1.60-RXN N-(long-chain-acyl)ethanolamine amidohydrolase activity|N-acylethanolamine amidohydrolase activity|acylethanolamine amidase activity Catalysis of the reaction: H2O + N-(long-chain-acyl)ethanolamine = ethanolamine + a fatty acid. GO:0047411 2-(acetamidomethylene)succinate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047411 EC:3.5.1.29|RHEA:10432|MetaCyc:3.5.1.29-RXN 2-(acetamidomethylene)succinate amidohydrolase (deaminating, decarboxylating)|alpha-(N-acetylaminomethylene)succinic acid hydrolase activity Catalysis of the reaction: 2 H2O + 2-(acetamidomethylene)succinate = CO2 + NH3 + succinate semialdehyde + acetate. GO:0047410 N-formylmethionylaminoacyl-tRNA deformylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047410 MetaCyc:3.5.1.27-RXN N-formyl-L-methionylaminoacyl-tRNA amidohydrolase activity Catalysis of the reaction: H2O + charged-fMet-tRNAs = L-methionylaminoacyl-tRNA + formate. CHEBI:83057 Daphnia metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83057 CHEBI:83056 Daphnia magna metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83056 UBERON:0001394 axillary artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001394 axillary part of trunk of subclavian artery|arteria axillaris|axillary part of subclavian artery Artery that supplies the axilla CHEBI:83054 1-stearoyl-sn-glycero-3-phospho-1D-myo-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83054 GO:0047419 N-acetylgalactosamine-6-phosphate deacetylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047419 MetaCyc:3.5.1.80-RXN|EC:3.5.1.25|RHEA:18149 Catalysis of the reaction: H2O + N-acetyl-D-galactosamine 6-phosphate = acetate + D-galactosamine 6-phosphate. CHEBI:10115 zingiberene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_10115 GO:0047418 phthalyl amidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047418 EC:3.5.1.79|RHEA:18297|MetaCyc:3.5.1.79-RXN phthalyl-amide amidohydrolase activity|o-phthalyl amidase activity Catalysis of the reaction: H2O + a phthalylamide = phthalate + substituted amine. GO:0047417 N-carbamoyl-D-amino acid hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047417 EC:3.5.1.77|RHEA:11000|MetaCyc:3.5.1.77-RXN N-carbamoyl-D-amino acid amidohydrolase activity Catalysis of the reaction: H2O + N-carbamoyl-D-amino acid = CO2 + NH3 + D-amino acid. CHEBI:24769 iduronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24769 CHEBI:24773 3-(imidazol-5-yl)lactate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_24773 CHEBI:24779 imidazolylacetaldehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24779 CHEBI:48726 nitroanisoles biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48726 GO:0047427 cyanoalanine nitrilase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047427 MetaCyc:3.5.5.4-RXN|KEGG_REACTION:R00486|EC:3.5.5.4|RHEA:11188 3-cyano-L-alanine aminohydrolase activity|beta-cyanoalanine nitrilase activity Catalysis of the reaction: 3-cyano-L-alanine + 2 H(2)O + H(+) = L-aspartate + NH(4)(+). GO:0047426 ricinine nitrilase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047426 RHEA:22704|MetaCyc:3.5.5.2-RXN|EC:3.5.5.2 ricinine aminohydrolase activity Catalysis of the reaction: H2O + ricinine = NH3 + 3-carboxy-4-methoxy-N-methyl-2-pyridone. GO:0047425 1-pyrroline-4-hydroxy-2-carboxylate deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047425 KEGG_REACTION:R02280|MetaCyc:3.5.4.22-RXN|EC:3.5.4.22|RHEA:10560 HPC deaminase activity|1-pyrroline-4-hydroxy-2-carboxylate aminohydrolase (decyclizing) Catalysis of the reaction: 4-hydroxy-1-pyrroline-2-carboxylate + H(2)O + H(+) = 2,5-dioxopentanoate + NH(4)(+). GO:0047424 methylenediurea deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047424 MetaCyc:3.5.3.21-RXN|RHEA:15929|EC:3.5.3.21 methylenediurease activity|methylenediurea aminohydrolase activity Catalysis of the reaction: 2 H2O + methylenediurea = CO2 + 2 NH3 + N-hydroxymethylurea. CHEBI:10106 zearalenone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_10106 GO:0047423 N-methylhydantoinase (ATP-hydrolyzing) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047423 MetaCyc:3.5.2.14-RXN|EC:3.5.2.14|RHEA:11720|Wikipedia:N-methylhydantoinase_(ATP-hydrolysing)|KEGG_REACTION:R03187 N-methylhydantoinase (ATP-hydrolysing)|N-methylhydantoin amidohydrolase activity|methylhydantoin amidase activity|N-methylhydantoinase activity|N-methylhydantoin hydrolase activity|N-methylimidazolidine-2,4-dione amidohydrolase (ATP-hydrolysing) Catalysis of the reaction: N-methylhydantoin + ATP + 2 H(2)O = N-carbamoylsarcosine + ADP + 3 H(+) + phosphate. GO:0047422 N-acyl-D-aspartate deacylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047422 KEGG_REACTION:R02182|RHEA:18285|MetaCyc:3.5.1.83-RXN|EC:3.5.1.83 N-acyl-D-aspartate amidohydrolase activity Catalysis of the reaction: N-acyl-D-aspartate + H(2)O = D-aspartate + a carboxylate. GO:0047421 N-acyl-D-glutamate deacylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047421 MetaCyc:3.5.1.82-RXN|RHEA:12833|EC:3.5.1.82|KEGG_REACTION:R01581 N-acyl-D-glutamate amidohydrolase activity Catalysis of the reaction: N-acyl-D-glutamate + H(2)O = D-glutamate + a carboxylate. GO:0047420 N-acyl-D-amino-acid deacylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047420 MetaCyc:3.5.1.81-RXN|RHEA:18309|EC:3.5.1.81 D-aminoacylase activity|N-acyl-D-amino acid amidohydrolase activity Catalysis of the reaction: H2O + N-acyl-D-amino acid = D-amino acid + an acid. UBERON:0001383 muscle of leg biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001383 skeletal muscle of leg|muscle of upper/lower leg|muscle of thigh or crus|leg skeletal muscle|leg muscle|muscle organ of leg|muscle of upper or lower hindlimb segment|leg skeletal muscle tissue|muscle of hindlimb zeugopod or stylopod|leg muscle organ A muscle that is part of the region of the hindlimb between the pelvis and ankle. CHEBI:83064 3'-end ribonucleotide 2',3'-cyclic phosphate(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83064 GO:0047429 nucleoside-triphosphate diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047429 MetaCyc:3.6.1.19-RXN|EC:3.6.1.9 nucleoside-triphosphate diphosphohydrolase activity|nucleoside-triphosphate pyrophosphatase activity Catalysis of the reaction: H2O + a nucleoside triphosphate = diphosphate + a nucleotide. CHEBI:83062 3'-end ribonucleotide 3'-phosphate(3-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83062 GO:0047428 arylacetonitrilase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047428 RHEA:20657|MetaCyc:3.5.5.5-RXN|EC:3.5.5.5 arylacetonitrile aminohydrolase activity Catalysis of the reaction: 2 H2O + 4-chlorophenylacetonitrile = 4-chlorophenylacetate + NH3. GO:0047430 oligosaccharide-diphosphodolichol diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047430 EC:3.6.1.44|RHEA:15205|MetaCyc:3.6.1.44-RXN oligosaccharide-diphosphodolichol pyrophosphatase activity|oligosaccharide-diphosphodolichol phosphodolichohydrolase activity Catalysis of the reaction: H2O + oligosaccharide-diphosphodolichol = dolichol-phosphate + oligosaccharide phosphate. CHEBI:24745 hydroxypyridine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24745 CHEBI:24744 2-hydroxypropyl-CoM biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24744 GO:0047438 2-dehydro-3-deoxy-L-pentonate aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047438 EC:4.1.2.18|RHEA:18545|MetaCyc:4.1.2.18-RXN 2-keto-3-deoxy-D-xylonate aldolase activity|2-keto-3-deoxy-L-pentonate aldolase activity|2-dehydro-3-deoxy-L-pentonate glycolaldehyde-lyase activity|2-dehydro-3-deoxy-L-pentonate glycolaldehyde-lyase (pyruvate-forming)|3-deoxy-D-pentulosonic acid aldolase|2-keto-3-deoxy-L-arabonate aldolase activity Catalysis of the reaction: 2-dehydro-3-deoxy-L-pentonate = glycolaldehyde + pyruvate. GO:0047437 4-oxalocrotonate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047437 UM-BBD_reactionID:r1435|EC:4.1.1.77|RHEA:24260|MetaCyc:4.1.1.77-RXN 4-oxalocrotonate carboxy-lyase activity|4-oxalocrotonate carboxy-lyase (2-oxopent-4-enoate-forming) Catalysis of the reaction: 4-oxalocrotonate = CO2 + 2-oxopent-4-enoate. GO:0047436 arylmalonate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047436 RHEA:20513|EC:4.1.1.76|KEGG_REACTION:R05173|MetaCyc:4.1.1.76-RXN AMDase activity|2-aryl-2-methylmalonate carboxy-lyase activity|2-aryl-2-methylmalonate carboxy-lyase (2-arylpropanoate-forming)|AMDASE Catalysis of the reaction: 2-aryl-2-methylmalonate + H(+) = 2-arylpropionate + CO(2). GO:0047435 5-guanidino-2-oxopentanoate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047435 EC:4.1.1.75|KEGG_REACTION:R03178|RHEA:11340|MetaCyc:4.1.1.75-RXN 2-oxo-5-guanidinopentanoate carboxy-lyase (4-guanidinobutanal-forming)|2-oxo-5-guanidinopentanoate carboxy-lyase activity|2-oxo-5-guanidinopentanoate decarboxylase activity|alpha-ketoarginine decarboxylase activity|2-oxo-5-guanidinovalerate alpha-ketoarginine decarboxylase activity Catalysis of the reaction: 5-guanidino-2-oxopentanoate + H(+) = 4-guanidinobutanal + CO(2). GO:0047434 indolepyruvate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047434 EC:4.1.1.74|RHEA:18017|MetaCyc:4.1.1.74-RXN 3-(indol-3-yl)pyruvate carboxy-lyase activity|indole-3-pyruvate decarboxylase activity|indol-3-yl-pyruvate carboxy-lyase activity|3-(indol-3-yl)pyruvate carboxy-lyase [(2-indol-3-yl)acetaldehyde-forming] Catalysis of the reaction: indolepyruvate = CO2 + indole acetaldehyde. GO:0047433 branched-chain-2-oxoacid decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047433 RHEA:21108|EC:4.1.1.72|KEGG_REACTION:R03894|MetaCyc:4.1.1.72-RXN branched-chain keto acid decarboxylase activity|(3S)-3-methyl-2-oxopentanoate carboxy-lyase (2-methylbutanal-forming)|(3S)-3-methyl-2-oxopentanoate carboxy-lyase activity|branched-chain oxo acid decarboxylase activity|branched-chain alpha-keto acid decarboxylase activity|BCKA Catalysis of the reaction: (S)-3-methyl-2-oxopentanoate + H(+) = 2-methylbutanal + CO(2). GO:0047432 2,2-dialkylglycine decarboxylase (pyruvate) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047432 EC:4.1.1.64|KEGG_REACTION:R03854|RHEA:16073|MetaCyc:4.1.1.64-RXN alpha-dialkyl amino acid transaminase activity|2,2-dialkyl-2-amino acid-pyruvate aminotransferase activity|L-alanine-alpha-ketobutyrate aminotransferase activity|2,2-dialkylglycine carboxy-lyase (amino-transferring)|dialkyl amino acid (pyruvate) decarboxylase activity|2,2-dialkylglycine carboxy-lyase (amino-transferring; L-alanine-forming)|dialkylamino-acid decarboxylase (pyruvate) Catalysis of the reaction: 2,2-dialkylglycine + H(+) + pyruvate = L-alanine + CO(2) + dialkyl ketone. GO:0047431 3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047431 RHEA:13669|EC:4.1.1.51|KEGG_REACTION:R03461|MetaCyc:4.1.1.51-RXN 3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-carboxy-lyase (3-hydroxy-2-methylpyridine-5-carboxylate-forming)|3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-carboxy-lyase activity Catalysis of the reaction: 5-hydroxy-6-methylpyridine-3,4-dicarboxylate + H(+) = 5-hydroxy-6-methylpyridine-3-carboxylate + CO(2). GO:0047439 3-deoxy-D-manno-octulosonate aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047439 EC:4.1.2.23|KEGG_REACTION:R01576|RHEA:23340|MetaCyc:4.1.2.23-RXN 2-keto-3-deoxyoctonic aldolase activity|3-deoxy-D-manno-octulosonic aldolase activity|3-deoxyoctulosonic aldolase activity|3-deoxy-D-manno-octulosonate D-arabinose-lyase activity|3-deoxy-D-manno-octulosonate D-arabinose-lyase (pyruvate-forming)|2-keto-3-deoxyoctonate aldolase activity|KDOaldolase activity Catalysis of the reaction: 3-deoxy-D-manno-octulosonate = D-arabinose + pyruvate. OIO:hasOBOFormatVersion has_obo_format_version biolink:OntologyClass go-plus http://www.geneontology.org/formats/oboInOwl#hasOBOFormatVersion CHEBI:83072 EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83072 CHEBI:83071 tRNA 3'-terminal nucleotidyl-cytidyl-cytidyl-adenosine(4-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83071 CHEBI:48717 9,9',15-tri-cis-zeta-carotene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48717 CHEBI:48716 9,9'-di-cis-zeta-carotene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48716 CHEBI:24747 hydroxyoctadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24747 GO:0047441 5-dehydro-2-deoxyphosphogluconate aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047441 EC:4.1.2.29|KEGG_REACTION:R05378|MetaCyc:4.1.2.29-RXN|RHEA:13177 phospho-5-dehydro-2-deoxygluconate aldolase activity|5-dehydro-2-deoxy-D-gluconate-6-phosphate malonate-semialdehyde-lyase activity|5-dehydro-2-deoxy-D-gluconate-6-phosphate malonate-semialdehyde-lyase (pyruvate-forming)|phospho-5-keto-2-deoxygluconate aldolase activity Catalysis of the reaction: 6-phospho-5-dehydro-2-deoxy-D-gluconate = 3-oxopropanoate + glycerone phosphate. CHEBI:24753 hygromycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24753 GO:0047440 2-dehydro-3-deoxy-D-pentonate aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047440 RHEA:20609|EC:4.1.2.28|KEGG_REACTION:R01782|MetaCyc:4.1.2.28-RXN 2-dehydro-3-deoxy-D-pentonate glycolaldehyde-lyase activity|3-deoxy-D-pentulosonic acid aldolase|2-keto-3-deoxy-D-pentonate aldolase activity Catalysis of the reaction: 2-dehydro-3-deoxy-D-arabinonate = glycolaldehyde + pyruvate. CHEBI:24751 hydroxytoluene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24751 CHEBI:24757 hypochlorous acid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_24757 UBERON:0001359 cerebrospinal fluid biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001359 cerebral spinal fluid|liquor cerebrospinalis|CSF|spinal fluid A clear, colorless, bodily fluid, that occupies the subarachnoid space and the ventricular system around and inside the brain and spinal cord. CHEBI:48701 7alpha,24-dihydroxycholest-4-en-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48701 GO:0047449 2-dehydro-3-deoxy-L-arabinonate dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047449 MetaCyc:4.2.1.43-RXN|EC:4.2.1.43|KEGG_REACTION:R02278|RHEA:17201 2-dehydro-3-deoxy-L-arabinonate hydro-lyase activity|2-dehydro-3-deoxy-L-arabinonate hydro-lyase (2,5-dioxopentanoate-forming)|2-keto-3-deoxy-L-arabinonate dehydratase activity Catalysis of the reaction: 2-dehydro-3-deoxy-L-arabinonate = 2,5-dioxopentanoate + H(2)O. GO:0047448 5-dehydro-4-deoxyglucarate dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047448 MetaCyc:4.2.1.41-RXN|RHEA:24608|EC:4.2.1.41|KEGG_REACTION:R02279 5-dehydro-4-deoxy-D-glucarate hydro-lyase (decarboxylating; 2,5-dioxopentanoate-forming)|5-keto-4-deoxy-glucarate dehydratase activity|5-dehydro-4-deoxy-D-glucarate hydro-lyase (decarboxylating)|deoxyketoglucarate dehydratase activity|D-4-deoxy-5-ketoglucarate hydro-lyase activity Catalysis of the reaction: 5-dehydro-4-deoxy-D-glucarate + H(+) = 2,5-dioxopentanoate + CO(2) + H(2)O. GO:0047447 erythro-3-hydroxyaspartate ammonia-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047447 MetaCyc:4.3.1.20-RXN|EC:4.3.1.20|RHEA:19757 erythro-3-hydroxy-L(s)-aspartate hydro-lyase (deaminating) activity|3-hydroxyaspartate dehydratase activity|erythro-3-hydroxy-Ls-aspartate ammonia-lyase activity|erythro-3-hydroxy-Ls-aspartate ammonia-lyase (oxaloacetate-forming)|erythro-3-hydroxy-Ls-aspartate hydro-lyase (deaminating)|erythro-3-hydroxyaspartate dehydratase activity|erythro-beta-hydroxyaspartate dehydratase activity Catalysis of the reaction: erythro-3-hydroxy-L-aspartate = NH3 + oxaloacetic acid. GO:0047446 (1-hydroxycyclohexan-1-yl)acetyl-CoA lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047446 MetaCyc:4.1.3.35-RXN|RHEA:23868|EC:4.1.3.35|KEGG_REACTION:R02232 (1-hydroxycyclohexan-1-yl)acetyl-CoA cyclohexanone-lyase (acetyl-CoA-forming)|(1-hydroxycyclohexan-1-yl)acetyl-CoA cyclohexanone-lyase activity Catalysis of the reaction: (1-hydroxycyclohexan-1-yl)acetyl-CoA = acetyl-CoA + cyclohexanone. GO:0047445 3-hydroxy-3-isohexenylglutaryl-CoA lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047445 RHEA:23084|MetaCyc:4.1.3.26-RXN|KEGG_REACTION:R08090|EC:4.1.3.26|UM-BBD_reactionID:r1168 3-hydroxy-3-isohexenylglutaryl coenzyme A lyase activity|beta-hydroxy-beta-isohexenylglutaryl CoA-lyase activity|hydroxyisohexenylglutaryl-CoA:acetatelyase activity|3-hydroxy-3-isohexenylglutaryl-CoA isopentenylacetoacetyl-CoA-lyase activity|3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA acetate-lyase (7-methyl-3-oxooct-6-enoyl-CoA-forming)|3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA acetate-lyase activity Catalysis of the reaction: 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA + 4 H(+) = 7-methyl-3-oxooct-6-enoyl-CoA + acetate. GO:0047444 N-acylneuraminate-9-phosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047444 Reactome:R-HSA-4084976|MetaCyc:4.1.3.20-RXN|EC:2.5.1.57|RHEA:13421 N-acetylneuraminate 9-phosphate synthetase activity|N-acylneuraminate-9-phosphate pyruvate-lyase (pyruvate-phosphorylating) activity|N-acetylneuraminate 9-phosphate sialic acid 9-phosphate synthase activity|phosphoenolpyruvate:N-acyl-D-mannosamine-6-phosphate 1-(2-carboxy-2-oxoethyl)transferase activity|N-acetylneuraminate 9-phosphate lyase activity|sialic acid 9-phosphate synthetase activity|N-acetylneuraminic acid phosphate synthase activity Catalysis of the reaction: H2O + phosphoenolpyruvate + N-acyl-D-mannosamine 6-phosphate = phosphate + N-acylneuraminate 9-phosphate. GO:0047443 4-hydroxy-4-methyl-2-oxoglutarate aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047443 EC:4.1.3.17|RHEA:22748|MetaCyc:4.1.3.17-RXN 4-hydroxy-4-methyl-2-oxoglutarate pyruvate-lyase activity|4-hydroxy-4-methyl-2-ketoglutarate aldolase activity|pyruvate aldolase activity|4-hydroxy-4-methyl-2-oxoglutarate pyruvate-lyase (pyruvate-forming)|gamma-methyl-gamma-hydroxy-alpha-ketoglutaric aldolase activity Catalysis of the reaction: 4-hydroxy-4-methyl-2-oxoglutarate = 2 pyruvate. GO:0047442 17-alpha-hydroxyprogesterone aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047442 MetaCyc:4.1.2.30-RXN|EC:4.1.2.30|RHEA:14753 C-17/C-20 lyase activity|17alpha-hydroxyprogesterone acetaldehyde-lyase (4-androstene-3,17-dione-forming)|17alpha-hydroxyprogesterone aldolase activity|17alpha-hydroxyprogesterone acetaldehyde-lyase activity|17-alpha-hydroxyprogesterone acetaldehyde-lyase activity Catalysis of the reaction: 17-alpha-hydroxyprogesterone = acetaldehyde + 4-androstene-3,17-dione. CHEBI:83088 (R)-lipoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83088 CHEBI:48706 antagonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48706 CHEBI:48705 agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48705 UBERON:0001366 parietal peritoneum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001366 parietal serous membrane of peritoneum|peritoneal cavity lining The outer layer of peritoneum that is attached to the abdominal and pelvic walls. GO:0047452 protoaphin-aglucone dehydratase (cyclizing) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047452 RHEA:23876|KEGG_REACTION:R03742|EC:4.2.1.73|MetaCyc:4.2.1.73-RXN protoaphin-aglucone hydro-lyase (cyclizing; xanthoaphin-forming)|protoaphin dehydratase activity|protoaphin dehydratase (cyclizing)|protoaphin-aglucone hydro-lyase (cyclizing) Catalysis of the reaction: protoaphin aglucone = H(2)O + xanthoaphin. GO:0047451 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047451 KEGG_REACTION:R04537|MetaCyc:4.2.1.59-RXN|EC:4.2.1.59|RHEA:41844 3-hydroxyoctanoyl-[acyl-carrier protein] dehydratase activity|D-3-hydroxyoctanoyl-acyl carrier protein dehydratase activity|D-3-hydroxyoctanoyl-[acyl carrier protein] dehydratase activity|(3R)-3-hydroxyoctanoyl-[acyl-carrier-protein] hydro-lyase activity|beta-hydroxyoctanoyl thioester dehydratase activity|beta-hydroxyoctanoyl-acyl carrier protein dehydrase activity|3-hydroxyoctanoyl-ACP dehydratase activity|(3R)-3-hydroxyoctanoyl-acyl-carrier-protein hydro-lyase (oct-2-enoyl-acyl-carrier protein-forming)|(3R)-3-hydroxyoctanoyl-acyl-carrier-protein hydro-lyase activity|beta-hydroxyoctanoyl-ACP-dehydrase activity|3-hydroxyoctanoyl-acyl-carrier-protein dehydratase activity Catalysis of the reaction: (3R)-3-hydroxyoctanoyl-[acyl-carrier protein] = H2O + 2-octenoyl-[acyl-carrier protein]. GO:0047450 crotonoyl-[acyl-carrier-protein] hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047450 MetaCyc:4.2.1.58-RXN|EC:4.2.1.58|KEGG_REACTION:R04428 3-hydroxybutyryl acyl carrier protein dehydratase activity|(3R)-3-hydroxybutanoyl-[acyl-carrier-protein] hydro-lyase activity|(3R)-3-hydroxybutanoyl-acyl-carrier-protein hydro-lyase (but-2-enoyl-acyl-carrier protein-forming)|beta-hydroxybutyryl acyl carrier protein dehydrase activity|enoyl acyl carrier protein hydrase activity|crotonyl acyl carrier protein hydratase activity|(3R)-3-hydroxybutanoyl-acyl-carrier-protein hydro-lyase activity|crotonoyl-ACP hydratase activity|beta-hydroxybutyryl acyl carrier protein (ACP) dehydrase activity|crotonoyl-acyl-carrier-protein hydratase activity|crotonoyl-[acyl-carrier protein] hydratase activity Catalysis of the reaction: (3R)-3-hydroxybutanoyl-[acyl-carrier protein] = H2O + but-2-enoyl-[acyl-carrier protein]. GO:0047459 3-aminobutyryl-CoA ammonia-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047459 EC:4.3.1.14|RHEA:10056|KEGG_REACTION:R03030|MetaCyc:4.3.1.14-RXN L-3-aminobutyryl-CoA ammonia-lyase (crotonoyl-CoA-forming)|L-3-aminobutyryl-CoA ammonia-lyase activity|L-3-aminobutyryl-CoA deaminase activity Catalysis of the reaction: (S)-3-aminobutanoyl-CoA = crotonoyl-CoA + NH(4)(+). GO:0047458 beta-pyrazolylalanine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047458 RHEA:13117|EC:2.5.1.51|KEGG_REACTION:R03134|MetaCyc:2.5.1.51-RXN pyrazolylalaninase activity|3-O-acetyl-L-serine:pyrazole 1-(2-amino-2-carboxyethyl)transferase activity|O3-acetyl-L-serine acetate-lyase (adding pyrazole)|beta-(1-pyrazolyl)alanine synthase activity|BPA-synthase activity|O(3)-acetyl-L-serine acetate-lyase (adding pyrazole) activity|beta-pyrazolealanine synthase activity|pyrazolealanine synthase activity|O3-acetyl-L-serine:pyrazole 1-(2-amino-2-carboxyethyl)transferase activity|beta-pyrazolylalanine synthase (acetylserine) activity Catalysis of the reaction: O-acetyl-L-serine + pyrazole = 3-(pyrazol-1-yl)-L-alanine + acetate + H(+). GO:0047457 exo-(1,4)-alpha-D-glucan lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047457 EC:4.2.2.13|MetaCyc:4.2.2.13-RXN exo-alpha-1,4-glucan lyase activity|(1->4)-alpha-D-glucan exo-4-lyase (1,5-anhydro-D-fructose-forming)|alpha-(1->4)-glucan 1,5-anhydro-D-fructose eliminase activity|exo-(1->4)-alpha-D-glucan lyase activity|alpha-1,4-glucan 1,5-anhydro-D-fructose eliminase activity|alpha-1,4-glucan lyase activity|alpha-1,4-glucan exo-lyase activity Catalysis of the reaction: linear alpha-D-glucan = 1,5-anhydro-D-fructose + beta-D-glucose. GO:0047456 2-methylisocitrate dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047456 EC:4.2.1.99|KEGG_REACTION:R04425|RHEA:17941|MetaCyc:4.2.1.99-RXN (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate hydro-lyase activity|(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate hydro-lyase [(Z)-but-2-ene-1,2,3-tricarboxylate-forming] Catalysis of the reaction: (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = cis-2-methylaconitate + H(2)O. GO:0047455 16-alpha-hydroxyprogesterone dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047455 EC:4.2.1.98|RHEA:12584|MetaCyc:4.2.1.98-RXN 16-alpha-hydroxyprogesterone dehydroxylase activity|16-alpha-dehydroxylase activity|16alpha-hydroxyprogesterone dehydroxylase activity|16alpha-dehydroxylase activity|16alpha-hydroxyprogesterone dehydratase activity|16alpha-hydroxyprogesterone hydro-lyase (16,17-didehydroprogesterone-forming)|16alpha-hydroxyprogesterone hydro-lyase activity|hydroxyprogesterone dehydroxylase activity|16-dehydroprogesterone hydratase activity Catalysis of the reaction: 16-alpha-hydroxyprogesterone = H2O + 16-dehydroprogesterone. GO:0047454 phaseollidin hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047454 EC:4.2.1.97|RHEA:19769|MetaCyc:4.2.1.97-RXN|KEGG_REACTION:R04728 phaseollidin-hydrate hydro-lyase activity|phaseollidin-hydrate hydro-lyase (phaseollidin-forming) Catalysis of the reaction: phaseollidin hydrate = H(2)O + phaseollidin. GO:0047453 ATP-dependent NAD(P)H-hydrate dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047453 EC:4.2.1.93|RHEA:19017|Reactome:R-HSA-6806967|MetaCyc:4.2.1.93-RXN|KEGG_REACTION:R00129 (6S)-beta-6-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase (ATP-hydrolysing)|ATP-dependent H4NAD(P)OH dehydratase activity|reduced nicotinamide adenine dinucleotide hydrate dehydratase activity|ATP-dependent H(4)NAD(P)OH dehydratase activity|(6S)-beta-6-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase(ATP-hydrolysing; NADH-forming) Catalysis of the reaction: (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide adenine dinucleotide + ATP = ADP + 3 H(+) + NADH + phosphate. CHEBI:83099 N(6)-[(R)-lipoyl]-L-lysine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83099 GO:0072419 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072419 CHEBI:83096 (R)-S(6)-acetyldihydrolipoamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83096 GO:0072418 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072418 GO:0072417 response to spindle checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072417 response to signal involved in spindle checkpoint|spindle checkpoint effector process A process that occurs in response to signals generated as a result of spindle checkpoint signaling. CHEBI:83094 (R)-lipoamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83094 GO:0072416 signal transduction involved in spindle checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072416 A signal transduction process that contributes to a spindle checkpoint. CHEBI:83093 (R)-dihydrolipoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83093 GO:0072415 detection of stimulus involved in spindle checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072415 spindle checkpoint sensor mechanism|sensing involved in spindle checkpoint|spindle checkpoint sensor process The series of events in which information about the assembly, orientation or integrity of the spindle is received and converted into a molecular signal, contributing to a spindle checkpoint. CHEBI:24727 hydroxynaphthalene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24727 GO:0072414 response to mitotic cell cycle checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072414 response to signal involved in mitotic cell cycle checkpoint|response to mitotic G2/M transition checkpoint signal|response to signal involved in mitotic cell cycle G1/S checkpoint|mitotic G2/M transition checkpoint effector process|response to signal involved in mitotic G2/M transition checkpoint|mitotic cell cycle G1/S checkpoint effector process|mitotic cell cycle checkpoint effector process|response to mitotic cell cycle G1/S checkpoint signaling A process that occurs in response to signals generated as a result of mitotic cell cycle checkpoint signaling. CHEBI:83091 (R)-lipoyl-AMP(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83091 GO:0072413 signal transduction involved in mitotic cell cycle checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072413 signal transduction involved in mitotic cell cycle G1/S checkpoint|signal transduction involved in mitotic G2/M transition checkpoint A signal transduction process that contributes to a mitotic cell cycle checkpoint. GO:0072412 detection of stimulus involved in mitotic cell cycle checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072412 sensing involved in mitotic cell cycle G1/S checkpoint|sensing involved in mitotic cell cycle checkpoint|mitotic cell cycle G1/S checkpoint sensor process|mitotic cell cycle checkpoint sensor mechanism|mitotic cell cycle checkpoint sensor process|mitotic cell cycle G1/S checkpoint sensor mechanism|detection of stimulus involved in mitotic cell cycle G1/S checkpoint The series of events in which information about a biological process or quality is received and converted into a molecular signal, contributing to a mitotic cell cycle checkpoint. GO:0072411 signal transduction involved in meiotic cell cycle checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072411 A signal transduction process that contributes to a meiotic cell cycle checkpoint. GO:0072410 response to meiotic cell cycle checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072410 response to signal involved in meiotic cell cycle checkpoint|meiotic cell cycle checkpoint effector process A process that acts directly to delay or stop progression through the cell cycle in response to signals generated as a result of meiotic cell cycle checkpoint signaling; contributes to a meiotic cell cycle checkpoint. CHEBI:24729 6-hydroxynicotine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24729 CHEBI:24731 hydroxyphenylacetaldehyde oxime biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24731 SO:0000110 sequence_feature biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000110 located_sequence_feature|located sequence feature|INSDC_note:other|INSDC_feature:misc_feature|sequence feature|INSDC_note:sequence_feature Any extent of continuous biological sequence. GO:0047463 2-aminohexano-6-lactam racemase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047463 EC:5.1.1.15|KEGG_REACTION:R04736|RHEA:14813|MetaCyc:5.1.1.15-RXN 2-amino-hexano-6-lactam racemase activity|alpha-amino-epsilon-caprolactam racemase activity Catalysis of the reaction: L-2-aminohexano-6-lactam = D-2-aminohexano-6-lactam. GO:0047462 phenylalanine racemase (ATP-hydrolyzing) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047462 EC:5.1.1.11|KEGG_REACTION:R00686|RHEA:20201|MetaCyc:5.1.1.11-RXN phenylalanine racemase (adenosine triphosphate-hydrolysing)|phenylalanine racemase (ATP-hydrolysing)|gramicidin S synthetase I|phenylalanine racemase activity Catalysis of the reaction: L-phenylalanine + ATP + H(2)O = D-phenylalanine + AMP + diphosphate + 2 H(+). CHEBI:24730 hydroxynitrile biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24730 GO:0047461 (+)-delta-cadinene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047461 MetaCyc:4.6.1.11-RXN|EC:4.2.3.13|RHEA:19525 2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, (+)-delta-cadinene-forming)|D-cadinene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + (+)-delta-cadinene. GO:0047460 L-2-amino-4-chloropent-4-enoate dehydrochlorinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047460 KEGG_REACTION:R02605|MetaCyc:4.5.1.4-RXN|RHEA:11620|EC:4.5.1.4 L-2-amino-4-chloro-4-pentenoate dehalogenase activity|L-2-amino-4-chloropent-4-enoate chloride-lyase (adding H2O; deaminating; 2-oxopent-4-enoate-forming)|L-2-amino-4-chloropent-4-enoate chloride-lyase (deaminating) Catalysis of the reaction: L-2-amino-4-chloropent-4-enoate + H(2)O = 2-oxopent-4-enoate + chloride + H(+) + NH(4)(+). CHEBI:24734 hydroxyphenylalanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24734 GO:0047469 4-carboxymethyl-4-methylbutenolide mutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047469 KEGG_REACTION:R04510|MetaCyc:5.4.99.14-RXN|RHEA:19237|EC:5.4.99.14 4-methyl-2-enelactone methyl-isomerase activity|4-methyl-3-enelactone methyl isomerase activity|4-carboxymethyl-4-methylbut-2-en-1,4-olide methylmutase activity|4-methylmuconolactone methylisomerase activity|4-methyl-2-enelactone isomerase activity Catalysis of the reaction: 4-carboxymethyl-4-methylbut-2-en-1,4-olide = 4-carboxymethyl-3-methylbut-2-en-1,4-olide. GO:0047468 phosphoglucomutase (glucose-cofactor) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047468 MetaCyc:5.4.2.5-RXN|EC:5.4.2.5 glucose-1-phosphate phosphotransferase activity|alpha-D-glucose 1,6-phosphomutase (glucose-cofactor) Catalysis of the reaction: glucose-1-phosphate = glucose-6-phosphate; using D-glucose as a cofactor. GO:0047467 4-hydroxyphenylacetaldehyde-oxime isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047467 Catalysis of the reaction: (E)-4-hydroxyphenylacetaldehyde oxime = (Z)-4-hydroxyphenylacetaldehyde oxime. GO:0047466 2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047466 MetaCyc:5.2.1.10-RXN|RHEA:10924|UM-BBD_reactionID:r0278|EC:5.2.1.10|KEGG_REACTION:R04576 2-chlorocarboxymethylenebutenolide isomerase activity|2-chloro-4-carboxymethylenebut-2-en-1,4-olide cis-trans-isomerase activity|chlorodienelactone isomerase activity Catalysis of the reaction: cis-2-chloro-4-carboxymethylenebut-2-en-1,4-olide = trans-2-chloro-4-carboxymethylenebut-2-en-1,4-olide. GO:0047465 N-acylglucosamine-6-phosphate 2-epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047465 MetaCyc:5.1.3.9-RXN|RHEA:23932|EC:5.1.3.9 N-acyl-D-glucosamine-6-phosphate 2-epimerase activity|acylglucosamine-6-phosphate 2-epimerase activity|acylmannosamine phosphate 2-epimerase activity|acylglucosamine phosphate 2-epimerase activity|N-acetylglucosmamine 6-phosphate 2-epimerase activity|N-acetylmannosamine-6-phosphate 2-epimerase activity Catalysis of the reaction: N-acyl-D-glucosamine 6-phosphate = N-acyl-D-mannosamine 6-phosphate. GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047464 EC:5.1.3.17|RHEA:20197|MetaCyc:5.1.3.17-RXN poly[(1,4)-beta-D-glucuronosyl-(1,4)-N-sulfo-alpha-D-glucosaminyl] glucurono-5-epimerase activity|heparosan epimerase activity|D-glucuronyl C-5 epimerase activity|polyglucuronate epimerase activity|heparosan-N-sulphate-glucuronate 5-epimerase activity|heparosan-N-sulfate-D-glucuronosyl 5-epimerase activity|C-5 uronosyl epimerase activity Catalysis of the reaction: heparosan-N-sulfate D-glucuronate = heparosan-N-sulfate L-iduronate. GO:0072409 detection of stimulus involved in meiotic cell cycle checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072409 meiotic cell cycle checkpoint sensor process|sensing involved in meiotic cell cycle checkpoint|meiotic cell cycle checkpoint sensor mechanism The series of events in which information about a biological process or quality is received and converted into a molecular signal, contributing to a meiotic cell cycle checkpoint. GO:0072408 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072408 GO:0072407 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072407 GO:0072406 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072406 GO:0072405 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072405 GO:0072404 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072404 GO:0072403 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072403 GO:0072402 response to DNA integrity checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072402 DNA integrity checkpoint effector process|response to signal involved in DNA integrity checkpoint A process that occurs in response to signals generated as a result of DNA integrity checkpoint signaling. GO:0072401 signal transduction involved in DNA integrity checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072401 A signal transduction process that contributes to a DNA integrity checkpoint. GO:0072400 detection of stimulus involved in mitotic DNA integrity checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072400 mitotic G2/M transition decatenation checkpoint sensor process|DNA integrity checkpoint sensor mechanism|DNA integrity checkpoint sensor process|mitotic G2/M transition decatenation checkpoint sensor mechanism|detection of stimulus involved in mitotic G2/M transition decatenation checkpoint|sensing involved in mitotic G2/M transition decatenation checkpoint|sensing involved in DNA integrity checkpoint The series of events in which information about DNA integrity is received and converted into a molecular signal, contributing to a mitotic DNA integrity checkpoint. GO:0047474 long-chain fatty acid luciferin component ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047474 RHEA:20101|MetaCyc:6.2.1.19-RXN|EC:6.2.1.19 long-chain-fatty-acid:protein ligase (AMP-forming)|acyl-protein synthetase activity|long-chain-fatty-acid-luciferin-component ligase activity|long-chain-fatty-acid luciferin component ligase activity Catalysis of the reaction: protein + an acid + ATP = an acyl-protein thiolester + diphosphate + AMP. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22. GO:0072430 detection of DNA damage stimulus involved in mitotic G1 DNA damage checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072430 sensing involved in mitotic cell cycle G1/S transition DNA damage checkpoint|detection of DNA damage stimulus involved in mitotic cell cycle G1/S transition DNA damage checkpoint|mitotic cell cycle G1/S transition DNA damage checkpoint sensor mechanism|mitotic cell cycle G1/S transition DNA damage checkpoint sensor process The series of events in which information about damage to DNA is received and converted into a molecular signal, contributing to a mitotic cell cycle G1/S transition DNA damage checkpoint. GO:0047473 D-alanine [D-alanyl carrier protein] ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047473 MetaCyc:6.2.1.M5-RXN|EC:6.2.1.- D-alanine:poly(phosphoribitol) ligase (AMP-forming)|D-alanine-activating enzyme activity|D-alanine-poly(phosphoribitol) ligase activity|D-alanine-D-alanyl carrier protein ligase activity Catalysis of the ATP-dependent activation of D-alanine and its transfer as a thiol ester to the phosphopantheinyl prosthetic group of a D-alanyl carrier protein, according to the reaction: ATP + D-alanine + a [D-alaninyl carrier protein] = a D-alanyl-[D-alanyl carrier protein] + AMP + diphosphate. GO:0047472 3-carboxy-cis,cis-muconate cycloisomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047472 MetaCyc:5.5.1.2-RXN|EC:5.5.1.2|KEGG_REACTION:R03307|RHEA:23656 3-carboxymuconate lactonizing enzyme activity|2-carboxy-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing)|beta-carboxymuconate lactonizing enzyme activity|3-carboxymuconolactone hydrolase activity|CMLE activity Catalysis of the reaction: 2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoate = 3-carboxy-cis,cis-muconate + H(+). GO:0047471 maltose alpha-D-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047471 MetaCyc:5.4.99.16-RXN|RHEA:15145|EC:5.4.99.16 maltose glucosylmutase activity|trehalose synthase activity|maltose alpha-D-glucosylmutase activity Catalysis of the reaction: maltose = trehalose. GO:0047470 (1,4)-alpha-D-glucan 1-alpha-D-glucosylmutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047470 RHEA:13621|MetaCyc:5.4.99.15-RXN|EC:5.4.99.15 maltodextrin alpha-D-glucosyltransferase activity|malto-oligosyltrehalose synthase activity|(1->4)-alpha-D-glucan 1-alpha-D-glucosylmutase Catalysis of the reaction: 4-[(1->4)-alpha-D-glucosyl](n-1)-D-glucose = 1-alpha-D-[(1->4)-alpha-D-glucosyl](n-1)-alpha-D-glucopyranoside. GO:0047479 trypanothione synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047479 EC:6.3.1.9|RHEA:21532|MetaCyc:6.3.1.9-RXN glutathionylspermidine:glutathione ligase (ADP-forming)|TSR synthetase activity Catalysis of the reaction: reduced glutathione + glutathionylspermidine + ATP = trypanothione + ADP + phosphate. GO:0047478 aspartate-ammonia ligase (ADP-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047478 MetaCyc:6.3.1.4-RXN|EC:6.3.1.4|KEGG_REACTION:R00482|RHEA:14197 asparagine synthetase (ADP-forming) activity|asparagine synthetase (adenosine diphosphate-forming)|L-aspartate:ammonia ligase (ADP-forming) Catalysis of the reaction: L-aspartate + ATP + NH(4)(+) = L-asparagine + ADP + 2 H(+) + phosphate. GO:0047477 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0047477 GO:0047476 3-alpha,7-alpha-dihydroxy-5-beta-cholestanate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047476 MetaCyc:6.2.1.28-RXN|EC:6.2.1.28|RHEA:21776 3alpha,7alpha-dihydroxy-5beta-cholestanoyl coenzyme A synthetase activity|DHCA-CoA ligase activity|3alpha,7alpha-dihydroxy-5beta-cholestanate-CoA ligase activity|3alpha,7alpha-dihydroxy-5beta-cholestanate:CoA ligase (AMP-forming) Catalysis of the reaction: CoA + 3-alpha,7-alpha-dihydroxy-5-beta-cholestanate + ATP = 3-alpha,7-alpha-dihydroxy-5-beta-cholestanoyl-CoA + diphosphate + AMP. GO:0047475 phenylacetate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047475 EC:6.2.1.30|MetaCyc:PHENYLACETATE--COA-LIGASE-RXN|RHEA:20956|KEGG_REACTION:R02539 phenylacetyl-CoA ligase activity|phenylacetyl-CoA ligase (AMP-forming)|PA-CoA ligase activity|phenacyl coenzyme A synthetase activity|phenylacetate:CoA ligase (AMP-forming) Catalysis of the reaction: ATP + CoA + phenylacetate = AMP + diphosphate + H(+) + phenylacetyl-CoA. GO:0072439 detection of stimulus involved in meiotic DNA replication checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072439 meiotic DNA replication checkpoint sensor mechanism|meiotic DNA replication checkpoint sensor process|sensing involved in meiotic DNA replication checkpoint The series of events in which information about whether DNA replication is complete is received and converted into a molecular signal, contributing to a meiotic DNA replication checkpoint. GO:0072438 response to DNA replication checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072438 DNA replication checkpoint effector process|response to signal involved in DNA replication checkpoint A process that occurs in response to signals generated as a result of DNA replication checkpoint signaling. CHEBI:24705 hydroxykynurenamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24705 GO:0072437 signal transduction involved in DNA replication checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072437 A signal transduction process that contributes to a DNA replication checkpoint. GO:0072436 detection of stimulus involved in DNA replication checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072436 sensing involved in DNA replication checkpoint|DNA replication checkpoint sensor mechanism|DNA replication checkpoint sensor process The series of events in which information about whether DNA replication is complete is received and converted into a molecular signal, contributing to a DNA replication checkpoint. GO:0072435 response to mitotic G2 DNA damage checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072435 response to signal involved in mitotic G2/M transition decatenation checkpoint|mitotic G2/M transition DNA damage checkpoint effector process|response to mitotic G2/M transition DNA damage checkpoint signaling|mitotic G2/M transition decatenation checkpoint effector process|response to mitotic G2/M transition decatenation checkpoint signaling|response to signal involved in mitotic G2/M transition DNA damage checkpoint A process that occurs in response to signals generated as a result of mitotic G2/M transition DNA damage checkpoint signaling. GO:0072434 signal transduction involved in mitotic G2 DNA damage checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072434 signal transduction involved in mitotic G2/M transition DNA damage checkpoint A signal transduction process that contributes to a mitotic G2/M transition DNA damage checkpoint. GO:0072433 detection of DNA damage stimulus involved in mitotic G2 DNA damage checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072433 mitotic G2/M transition DNA damage checkpoint sensor mechanism|sensing involved in mitotic G2/M transition DNA damage checkpoint|mitotic G2/M transition DNA damage checkpoint sensor process|detection of DNA damage stimulus involved in mitotic G2/M transition DNA damage checkpoint The series of events in which information about damage to DNA is received and converted into a molecular signal, contributing to a mitotic G2/M transition DNA damage checkpoint. CHEBI:24709 hydroxylamines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24709 GO:0072432 response to G1 DNA damage checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072432 response to signal involved in mitotic cell cycle G1/S transition DNA damage checkpoint|mitotic cell cycle G1/S transition DNA damage checkpoint effector process|response to mitotic cell cycle G1/S transition DNA damage checkpoint signaling A process that occurs in response to signals generated as a result of G1/S transition DNA damage checkpoint signaling. GO:0072431 signal transduction involved in mitotic G1 DNA damage checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072431 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint A signal transduction process that contributes to a mitotic cell cycle G1/S transition DNA damage checkpoint. PR:000009182 insulin-like growth factor I biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000009182 IGF1|Igf-1|somatomedin|MGF|somatomedin-C|IGF-I|mechano growth factor A protein that is a translation product of the human IGF1 gene or a 1:1 ortholog thereof. GO:0047485 protein N-terminus binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047485 amino-terminus binding|NH2-terminal binding|N-terminal end binding|NH2-terminus binding|N-terminal binding|amino-terminal binding Interacting selectively and non-covalently with a protein N-terminus, the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue. GO:0047484 regulation of response to osmotic stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0047484 Any process that modulates the rate or extent of the response to osmotic stress. GO:0047483 imidazoleacetate-phosphoribosyldiphosphate ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047483 MetaCyc:6.3.4.8-RXN|EC:6.3.4.8|KEGG_REACTION:R04068|RHEA:16485 5-phosphoribosylimidazoleacetate synthetase activity|imidazoleacetate:5-phosphoribosyl-diphosphate ligase (ADP- and diphosphate-forming) Catalysis of the reaction: 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H(2)O + imidazol-4-ylacetate = 1-(5-phosphoribosyl)imidazol-4-ylacetate + ADP + diphosphate + 2 H(+) + phosphate. GO:0047482 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047482 MetaCyc:6.3.2.7-RXN|RHEA:17969|KEGG_REACTION:R02786|EC:6.3.2.7 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:L-lysine gamma-ligase (ADP-forming)|UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine synthetase activity|uridine diphospho-N-acetylmuramoylalanyl-D-glutamyllysine synthetase activity|MurE synthetase activity|L-lysine-adding enzyme activity|UPD-MurNAc-L-Ala-D-Glu:L-Lys ligase activity Catalysis of the reaction: L-lysine + ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate = ADP + 2 H(+) + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine. GO:0047481 D-alanine-alanyl-poly(glycerolphosphate) ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047481 EC:6.3.2.16|MetaCyc:6.3.2.16-RXN D-alanyl-alanyl-poly(glycerolphosphate) synthetase activity|D-alanylalanylpoly(phosphoglycerol) synthetase activity|D-alanine:membrane-acceptor ligase activity|D-alanine:alanyl-poly(glycerolphosphate) ligase (ADP-forming)|D-alanine-membrane acceptor-ligase activity|D-alanyl-poly(phosphoglycerol) synthetase activity Catalysis of the reaction: alanyl-poly(glycerolphosphate) + D-alanine + ATP = D-alanyl-alanyl-poly(glycerolphosphate) + phosphate + ADP. GO:0047480 UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047480 EC:6.3.2.10|RHEA:16085|MetaCyc:6.3.2.10-RXN UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine synthetase activity|UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine synthetase activity|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase activity|UDP-MurNAc-pentapeptide synthetase activity|UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine:D-alanyl-D-alanine ligase (ADP-forming)|UDP-N-acetylmuramoylalanyl-tripeptide-D-alanyl-D-alanine ligase activity|UDP-N-acetylmuramoylalanine-D-glutamyl-lysine--D-alanyl-D-alanine ligase activity|UDP-N-acetylmuramoylalanyl-D-glutamyl-lysine-D-alanyl-D-alanine ligase activity|UDP-MurNAc-L-Ala-D-Glu-L-Lys:D-Ala-D-Ala ligase activity|UDPacetylmuramoylpentapeptide synthetase activity|MurF synthetase activity|uridine diphosphoacetylmuramoylpentapeptide synthetase activity|UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-D-alanyl-D-alanine ligase activity Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine + ATP + D-alanyl-D-alanine = phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + ADP. CHEBI:24712 hydroxymethyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_24712 CHEBI:24711 hydroxymalonate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24711 GO:0047489 pectate disaccharide-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047489 MetaCyc:4.2.2.9-RXN|RHEA:57104|EC:4.2.2.9 Exo-PATE activity|exopolygalacturonate lyase activity|exopectate lyase activity|(1->4)-alpha-D-galacturonan reducing-end-disaccharide-lyase activity|exopectic acid transeliminase activity|exo-PATE|pectate exo-lyase activity|PATE activity|Exo-PGL activity|exo-PGL|exopolygalacturonic acid-trans-eliminase activity Catalysis of the reaction: a pectate = a pectate + 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate. This reaction is the eliminative cleavage of 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate from the reducing end of pectate, i.e. de-esterified pectin. GO:0047488 heparin lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047488 MetaCyc:4.2.2.7-RXN|EC:4.2.2.7 heparan sulfate lyase activity|heparinase activity|heparin eliminase activity Catalysis of the eliminative cleavage of polysaccharides containing 1,4-linked D-glucuronate or L-iduronate residues and 1,4-alpha-linked 2-sulfoamino-2-deoxy-6-sulfo-D-glucose residues to give oligosaccharides with terminal 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their nonreducing ends. GO:0047487 oligogalacturonide lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047487 RHEA:20269|EC:4.2.2.6|MetaCyc:OLIGOGALACTURONIDE-LYASE-RXN OGTE|oligogalacturonate lyase activity|unsaturated oligogalacturonate transeliminase activity Catalysis of the reaction: 4-(4-deoxy-alpha-D-gluc-4-enuronosyl)-D-galacturonate = 2 5-dehydro-4-deoxy-D-glucuronate. GO:0047486 chondroitin ABC lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047486 Catalysis of the eliminative degradation of polysaccharides containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucuronosyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups. GO:0072429 response to intra-S DNA damage checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072429 intra-S DNA damage checkpoint effector process|response to signal involved in intra-S DNA damage checkpoint A process that occurs in response to signals generated as a result of intra-S DNA damage checkpoint signaling. GO:0072428 signal transduction involved in intra-S DNA damage checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072428 A signal transduction process that contributes to an intra-S DNA damage checkpoint. GO:0072427 detection of DNA damage stimulus involved in intra-S DNA damage checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072427 intra-S DNA damage checkpoint sensor process|intra-S DNA damage checkpoint sensor mechanism|sensing involved in intra-S DNA damage checkpoint The series of events in which information about damage to DNA is received and converted into a molecular signal, contributing to an intra-S DNA damage checkpoint. GO:0072426 response to G2 DNA damage checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072426 response to signal involved in G2/M transition DNA damage checkpoint|G2/M transition DNA damage checkpoint effector process A process that occurs in response to signals generated as a result of G2/M transition DNA damage checkpoint signaling. GO:0072425 signal transduction involved in G2 DNA damage checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072425 signal transduction involved in G2/M transition DNA damage checkpoint A signal transduction process that contributes to a G2/M transition DNA damage checkpoint. GO:0072424 detection of DNA damage stimulus involved in G2 DNA damage checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072424 G2/M transition DNA damage checkpoint sensor process|sensing involved in G2/M transition DNA damage checkpoint|G2/M transition DNA damage checkpoint sensor mechanism|detection of DNA damage stimulus involved in G2/M transition DNA damage checkpoint The series of events in which information about damage to DNA is received and converted into a molecular signal, contributing to a G2/M transition DNA damage checkpoint. GO:0072423 response to DNA damage checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072423 response to signal involved in DNA damage checkpoint|DNA damage checkpoint effector process A process that occurs in response to signals generated as a result of DNA damage checkpoint signaling. GO:0072422 signal transduction involved in DNA damage checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072422 A signal transduction process that contributes to a DNA damage checkpoint. GO:0072421 detection of DNA damage stimulus involved in DNA damage checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072421 DNA damage checkpoint sensor mechanism|DNA damage checkpoint sensor process|sensing involved in DNA damage checkpoint The series of events in which information about damage to DNA is received and converted into a molecular signal, contributing to a DNA damage checkpoint. GO:0072420 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072420 UBERON:0001425 pectoral lymphatic vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001425 PL CHEBI:48691 3-(cis-5,6-dihydroxycyclohexa-1,3-dienyl)propanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48691 CHEBI:58013 aspulvinone H(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58013 CHEBI:58012 strictosidine aglycone(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58012 CHEBI:58011 (1R,2R,3R)-prephytoene diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58011 CHEBI:34047 1,2-dihydrostilbene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_34047 CHEBI:58010 (S)-3'-hydroxy-N-methylcoclaurinium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58010 UBERON:0001435 carpal bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001435 carpal skeleton bone|carpal|bone of carpus|carpus bone A bone that is part of the carpal skeleton. Examples: scaphoid, lunate, capitate[cjm]. UBERON:0001434 skeletal system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001434 skeleton system|set of all bones and joints|Skelettsystem Anatomical system that is a multi-element, multi-tissue anatomical cluster that consists of the skeleton and the articular system. CHEBI:58018 N(5)-formyl-5,6,7,8-tetrahydromethanopterin(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58018 CHEBI:58017 5-O-phosphonato-alpha-D-ribofuranosyl diphosphate(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58017 CHEBI:58016 1-guanidiniumyl-1-deoxy-scyllo-inositol(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58016 CHEBI:58015 7,8-dihydro-7,8-dihydroxykynurenate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58015 CHEBI:58014 1-alkyl-sn-glycerol 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58014 UBERON:0001419 skin of limb biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001419 limb zone of skin|zone of skin of limb|limb skin A zone of skin that is part of a limb [Automatically generated definition]. UBERON:0001418 skin of thorax biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001418 thorax zone of skin|upper body skin|thorax skin|thoracic skin|zone of skin of thorax A zone of skin that is part of a thorax [Automatically generated definition]. UBERON:0001415 skin of pelvis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001415 zone of skin of pelvis|pelvic skin|pelvis skin|pelvis zone of skin A zone of skin that is part of a pelvis [Automatically generated definition]. UBERON:0001417 skin of neck biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001417 neck skin|zone of skin of neck|neck zone of skin|zone of skin of neck (volume)|neck (volume) zone of skin A zone of skin that is part of a neck [Automatically generated definition]. UBERON:0001416 skin of abdomen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001416 abdomen skin|zone of skin of abdomen|skin of abdomen proper|abdominal skin|abdomen zone of skin A zone of skin that is part of an abdomen [Automatically generated definition]. CHEBI:48681 2,3-dihydroxycinnamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48681 CHEBI:48683 piperazinecarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48683 CHEBI:58002 L-erythrulose 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58002 CHEBI:58001 primary aliphatic ammonium ion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58001 CHEBI:58000 D-glutamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58000 UBERON:0001422 facial lymphatic vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001422 buccal lymphatic vessel|lymph vessel of face|face lymph vessel|FL|lymphatic vessel of face|face lymphatic vessel A lymphatic vessel that is part of a face [Automatically generated definition]. UBERON:0001421 pectoral girdle region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001421 shoulder girdle|cingulum membri superioris|cingulum membri superioris|upper limb girdle|pectoral region|girdle - pectoral|pectoral girdle An organism subdivision that includes the pectoral girdle skeleton and associated soft tissue. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc). Examples: There are only two instances in an organism, right and left pectoral girdle regions. CHEBI:58009 L-gamma-glutamyl-L-cysteinyl-beta-alaninate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58009 CHEBI:58008 2-carboxylato-D-arabinitol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58008 CHEBI:58007 streptomycin(3+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58007 CHEBI:58006 Cypridina luciferin(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58006 CHEBI:58005 N-amidino-L-aspartate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58005 CHEBI:58004 3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58004 CHEBI:58003 3',5'-cyclic CMP(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58003 PR:000024939 interferon beta biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000024939 IFNB CHEBI:48676 fibrin modulating drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48676 CHEBI:73675 6''-O-carbamoylkanamycin A(4+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73675 CHEBI:48675 antifibrinolytic drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48675 CHEBI:73678 tobramycin(5+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73678 CHEBI:73677 (S)-alpha-hydroxyglutaric acid-gamma-lactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73677 CHEBI:48679 sorbopyranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48679 CHEBI:73679 nebramycin 5'(5+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73679 CHEBI:73672 cyclic ADP-ribose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73672 CHEBI:73674 carbamoyl adenylate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73674 CHEBI:73673 (S)-alpha-hydroxyglutarate-gamma-lactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73673 CHEBI:73687 L-threonylcarbamoyladenylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73687 CHEBI:48664 xylo-hexos-2-ulose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48664 CHEBI:73686 nebramycin 5' biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73686 CHEBI:48666 D-xylo-hexos-2-ulose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48666 CHEBI:73688 Ac-Asp-Glu biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73688 GO:0047603 acetoacetyl-CoA hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047603 EC:3.1.2.11|KEGG_REACTION:R01358|RHEA:15673|MetaCyc:ACETOACETYL-COA-HYDROLASE-RXN acetoacetyl coenzyme A hydrolase activity|acetoacetyl coenzyme A deacylase activity|acetoacetyl CoA deacylase activity Catalysis of the reaction: acetoacetyl-CoA + H(2)O = acetoacetate + CoA + H(+). GO:0047602 acetoacetate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047602 RHEA:19729|KEGG_REACTION:R01366|MetaCyc:ACETOACETATE-DECARBOXYLASE-RXN|EC:4.1.1.4 acetoacetate carboxy-lyase (acetone-forming)|acetoacetic acid decarboxylase activity|acetoacetate carboxy-lyase activity Catalysis of the reaction: acetoacetate + H(+) = acetone + CO(2). GO:0047601 acetate kinase (diphosphate) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047601 EC:2.7.2.12|KEGG_REACTION:R00320|RHEA:24276|MetaCyc:ACETATE-KINASE-PYROPHOSPHATE-RXN pyrophosphate-acetate phosphotransferase activity|diphosphate:acetate phosphotransferase activity|acetate kinase (pyrophosphate) activity Catalysis of the reaction: acetate + diphosphate = acetyl phosphate + phosphate. GO:0047600 abequosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047600 EC:2.4.1.60|RHEA:34183|MetaCyc:ABEQUOSYLTRANSFERASE-RXN trihexose diphospholipid abequosyltransferase activity|CDP-abequose:D-mannosyl-L-rhamnosyl-D-galactose-1-diphospholipid D-abequosyltransferase activity Catalysis of the reaction: CDP-abequose + D-mannosyl-L-rhamnosyl-D-galactose-1-diphospholipid = CDP + D-abequosyl-D-mannosyl-rhamnosyl-D-galactose-1-diphospholipid. GO:0047609 acetylputrescine deacetylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047609 RHEA:23412|KEGG_REACTION:R01156|EC:3.5.1.62|MetaCyc:ACETYLPUTRESCINE-DEACETYLASE-RXN N-acetylputrescine acetylhydrolase activity Catalysis of the reaction: N-acetylputrescine + H(2)O = acetate + putrescine. GO:0047608 acetylindoxyl oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047608 RHEA:16941|EC:1.7.3.2|MetaCyc:ACETYLINDOXYL-OXIDASE-RXN N-acetylindoxyl:oxygen oxidoreductase activity Catalysis of the reaction: N-acetylindoxyl + O2 = N-acetylisatin + unknown. GO:0047607 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0047607 GO:0047606 hydroxynitrilase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047606 EC:4.1.2.47|MetaCyc:ACETONE-CYANHYDRIN-LYASE-RXN 2-hydroxyisobutyronitrile acetone-lyase (cyanide-forming)|hydroxynitrile lyase activity|acetone-cyanhydrin lyase activity|acetone-cyanohydrin acetone-lyase activity|alpha-hydroxynitrile lyase activity|(S)-acetone-cyanohydrin lyase activity|acetone-cyanohydrin acetone-lyase (cyanide-forming)|oxynitrilase activity|2-hydroxyisobutyronitrile acetone-lyase activity|acetone-cyanohydrin lyase activity Catalysis of the reaction: a hydroxynitrile = cyanide + an aldehyde or ketone. GO:0047605 acetolactate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047605 RHEA:21580|EC:4.1.1.5|MetaCyc:ACETOLACTATE-DECARBOXYLASE-RXN alpha-acetolactate decarboxylase activity|(S)-2-hydroxy-2-methyl-3-oxobutanoate carboxy-lyase activity|(S)-2-hydroxy-2-methyl-3-oxobutanoate carboxy-lyase [(R)-2-acetoin-forming] Catalysis of the reaction: (S)-2-hydroxy-2-methyl-3-oxobutanoate = (R)-2-acetoin + CO2. GO:0047604 acetoin racemase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047604 MetaCyc:ACETOIN-RACEMASE-RXN|EC:5.1.2.4|RHEA:12092|KEGG_REACTION:R02949 acetylmethylcarbinol racemase activity Catalysis of the reaction: (S)-acetoin = (R)-acetoin. CHEBI:73680 carbamoyl adenylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73680 CHEBI:73683 6''-O-carbamoylkanamycin A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73683 CHEBI:73682 L-threonylcarbamoyladenylate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73682 CHEBI:73684 carbamoylkanamycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73684 CHEBI:24685 hydroxybutanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24685 CHEBI:24684 hydroxybutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24684 DDANAT:0010085 subdivision biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0010085 Anatomical structure which is a primary subdivision of whole Dictyostelium organism. The mereological sum of these is the whole organism. UBERON:0001469 sternoclavicular joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001469 articulatio sternoclavicularis|sternoclavicular|sterno clavicular joint|sternoclavicular articulation The sternoclavicular articulation is a double arthrodial joint composed of two portions separated by an articular disc. The parts entering into its formation are the sternal end of the clavicle, the upper and lateral part of the manubrium sterni, and the cartilage of the first rib, visible from the outside as the suprasternal notch. The articular surface of the clavicle is much larger than that of the sternum, and is invested with a layer of cartilage, which is considerably thicker than that on the latter bone. The ligaments of this joint are: Articular capsule Anterior sternoclavicular ligament Posterior sternoclavicular ligament Interclavicular ligament Costoclavicular ligament Articular disk [WP,unvetted]. CHEBI:48657 L-xylo-hexos-2-ulose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48657 CHEBI:24689 hydroxycinnamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24689 CHEBI:24688 monohydroxycinnamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24688 DDANAT:0010082 whole organism biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0010082 Anatomical structure that is an individual member of the Dictyostelium discoideum species and consists of more than one cell. GO:0047614 aconitate delta-isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047614 EC:5.3.3.7|MetaCyc:ACONITATE-DELTA-ISOMERASE-RXN|KEGG_REACTION:R02244|RHEA:17265 aconitate D-isomerase activity|aconitate delta2-delta3-isomerase activity|aconitate isomerase activity Catalysis of the reaction: trans-aconitate = cis-aconitate. GO:0047613 aconitate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047613 MetaCyc:ACONITATE-DECARBOXYLASE-RXN|KEGG_REACTION:R02243|EC:4.1.1.6|RHEA:15253 cis-aconitate carboxy-lyase (itaconate-forming)|cis-aconitate carboxy-lyase activity|CAD activity|cis-aconitic decarboxylase activity Catalysis of the reaction: cis-aconitate + H(+) = CO(2) + itaconate. GO:0047612 acid-CoA ligase (GDP-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047612 RHEA:10968|EC:6.2.1.10|KEGG_REACTION:R00394|MetaCyc:ACID--COA-LIGASE-GDP-FORMING-RXN acid:CoA ligase (GDP-forming)|acyl-CoA synthetase (GDP-forming) activity|acyl coenzyme A synthetase (guanosine diphosphate forming) Catalysis of the reaction: a carboxylate + CoA + GTP = acyl-CoA + GDP + H(+) + phosphate. GO:0047611 acetylspermidine deacetylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047611 RHEA:23928|MetaCyc:ACETYLSPERMIDINE-DEACETYLASE-RXN|EC:3.5.1.48|KEGG_REACTION:R07300 N(1)-acetylspermidine amidohydrolase activity|8-N-acetylspermidine amidohydrolase activity|N(8)-acetylspermidine deacetylase activity|N8-acetylspermidine deacetylase activity|N-acetylspermidine deacetylase activity|N(8)-monoacetylspermidine deacetylase activity|N8-monoacetylspermidine deacetylase activity|N1-acetylspermidine amidohydrolase activity|N8-acetylspermidine amidohydrolase activity|N(8)-acetylspermidine amidohydrolase activity Catalysis of the reaction: N(8)-acetylspermidine + H(2)O = acetate + spermidine. GO:0047610 acetylsalicylate deacetylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047610 MetaCyc:ACETYLSALICYLATE-DEACETYLASE-RXN|EC:3.1.1.55|KEGG_REACTION:R02942|RHEA:11752 aspirin esterase activity|acetylsalicylate O-acetylhydrolase activity|aspirin hydrolase activity|acetylsalicylic acid esterase activity Catalysis of the reaction: acetylsalicylate + H(2)O = acetate + H(+) + salicylate. CHEBI:48652 1,3-thiazolemonocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48652 CHEBI:24681 hydroxybiphenyls biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24681 CHEBI:34002 (3S)-3-Hydroxyadipyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_34002 GO:0047619 acylcarnitine hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047619 RHEA:17101|MetaCyc:ACYLCARNITINE-HYDROLASE-RXN|EC:3.1.1.28 carnitine ester hydrolase activity|long-chain acyl-L-carnitine hydrolase activity|palmitoyl-L-carnitine hydrolase activity|O-acylcarnitine acylhydrolase activity|high activity acylcarnitine hydrolase activity|palmitoylcarnitine hydrolase activity|HACH|palmitoyl carnitine hydrolase activity Catalysis of the reaction: O-acylcarnitine + H2O = a fatty acid + L-carnitine. UBERON:0001470 glenohumeral joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001470 articulatio humeri|humeroscapular joint|joint of shoulder|humeral joint|shoulder joint The glenohumeral joint, commonly known as the shoulder joint, is a multiaxial synovial ball and socket joint and involves articulation between the glenoid fossa of the scapula (shoulder blade) and the head of the humerus (upper arm bone). [WP,unvetted]. GO:0047618 acylagmatine amidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047618 RHEA:15065|KEGG_REACTION:R01425|EC:3.5.1.40|MetaCyc:ACYLAGMATINE-AMIDASE-RXN acylagmatine amidohydrolase activity|benzoylagmatine amidohydrolase activity|acylagmatine deacylase activity Catalysis of the reaction: N(4)-benzoylagmatine + H(2)O = agmatine + benzoate. GO:0047617 acyl-CoA hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047617 RHEA:16781|Reactome:R-HSA-5690042|Reactome:R-HSA-5690066|MetaCyc:ACYL-COA-HYDROLASE-RXN|EC:3.1.2.20|Reactome:R-HSA-5690043 acyl-CoA thiolesterase activity|acyl coenzyme A hydrolase activity|thioesterase B|acyl-CoA thioesterase activity|acyl-CoA thioesterase II activity|acyl-CoA thioesterase I activity|acyl coenzyme A thioesterase activity|thioesterase II Catalysis of the reaction: acyl-CoA + H2O = CoA + a carboxylate. PR:000010335 hepatocyte growth factor receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000010335 proto-oncogene c-Met|HGF receptor|scatter factor receptor|SF receptor|HGF/SF receptor|MET|tyrosine-protein kinase Met An HGF/MSP receptor type tyrosine-protein kinase that is a translation product of the human MET gene or a 1:1 ortholog thereof. GO:0047616 acyl-CoA dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047616 MetaCyc:ACYL-COA-DEHYDROGENASE-NADP+-RXN|EC:1.3.1.8|RHEA:22460 enoyl coenzyme A reductase activity|acyl-CoA:NADP+ 2-oxidoreductase activity|dehydrogenase, acyl coenzyme A (nicotinamide adenine dinucleotide phosphate)|2-enoyl-CoA reductase activity|crotonyl coenzyme A reductase activity Catalysis of the reaction: acyl-CoA + NADP+ = 2,3-dehydroacyl-CoA + NADPH + H+. CHEBI:34008 (R)-3-hydroxy-3-methyl-2-oxopentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_34008 GO:0047615 actinomycin lactonase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047615 EC:3.1.1.39|MetaCyc:ACTINOMYCIN-LACTONASE-RXN actinomycin lactonohydrolase activity Catalysis of the reaction: actinomycin + H2O = actinomycinic monolactone. CHEBI:10036 wax ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_10036 CHEBI:73690 erythrose 4-phosphate/phosphoenolpyruvate family amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73690 UBERON:0001476 deltoid biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001476 common shoulder muscle|musculus deltoideus|musculus deltoideus|deltoid muscle|deltoideus muscle|m. deltoideus|deltoideus A muscle of shoulder which attaches to the scapula, clavicle and humerus.[FMA,generalized] UBERON:0001479 sesamoid bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001479 sesamoid|ossa sesamoidea A sesamoid element that is composed of bone tissue. UBERON:0001473 lymphatic vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001473 vas lymphaticum|lymph vessel A vessel that contains or conveys lymph, that originates as an interfibrillar or intercellular cleft or space in a tissue or organ, and that if small has no distinct walls or walls composed only of endothelial cells and if large resembles a vein in structure[BTO]. UBERON:0001472 vaginal venous plexus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001472 venous vaginal plexus|plexus venosus vaginalis The vaginal plexuses are placed at the sides of the vagina; they communicate with the uterine, vesical, and hemorrhoidal plexuses, and are drained by the vaginal veins, one on either side, into the hypogastric veins. [WP,unvetted]. CHEBI:73693 ketone body biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73693 UBERON:0001474 bone element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001474 bone organ|bones|bone Skeletal element that is composed of bone tissue. CHEBI:48643 (2Z)-2-hydroxypenta-2,4-dienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48643 CHEBI:24698 hydroxyflavone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24698 CHEBI:24697 hydroxyflavanone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24697 UBERON:0001459 skin of external ear biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001459 outer ear zone of skin|auricular region zone of skin|zone of skin of external ear|external ear skin|zone of skin of auricular region of head|zone of skin of outer ear|auricular region of head zone of skin|external ear zone of skin|zone of skin of auricular region|ear skin A zone of skin that is part of a external ear [Automatically generated definition]. UBERON:0001458 skin of lip biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001458 lip zone of skin|zone of skin of lip|lip skin|skin of lips A zone of skin that is part of a lip [Automatically generated definition]. CHEBI:48649 L-sorbopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48649 CHEBI:24699 hydroxyfluorenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24699 GO:0047625 adenosylmethionine cyclotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047625 MetaCyc:ADENOSYLMETHIONINE-CYCLOTRANSFERASE-RXN|EC:2.5.1.4|KEGG_REACTION:R00180|RHEA:21932 S-adenosyl-L-methionine alkyltransferase (cyclizing)|adenosylmethioninase activity|adenosyl methionine cyclotransferase activity Catalysis of the reaction: S-adenosyl-L-methionine(1+) = S-methyl-5'-thioadenosine + homoserine lactone. GO:0047624 adenosine-tetraphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047624 EC:3.6.1.14|RHEA:24500|MetaCyc:ADENOSINE-TETRAPHOSPHATASE-RXN adenosine-tetraphosphate phosphohydrolase activity Catalysis of the reaction: adenosine 5'-tetraphosphate + H2O = ATP + phosphate. GO:0047623 adenosine-phosphate deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047623 MetaCyc:ADENOSINE-PHOSPHATE-DEAMINASE-RXN|EC:3.5.4.17 adenine nucleotide deaminase activity|adenosine (phosphate) deaminase activity|adenosine-phosphate aminohydrolase activity Catalysis of the reaction: an adenosine-phosphate + H20 = an inosine phosphate + NH3. Catalyzes the deamination of AMP, ADP or ATP. GO:0047622 adenosine nucleosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047622 RHEA:18669|MetaCyc:ADENOSINE-NUCLEOSIDASE-RXN|EC:3.2.2.7 N-ribosyladenine ribohydrolase activity|ANase activity|adenosine hydrolase activity|adenosinase activity|adenosine ribohydrolase activity Catalysis of the reaction: adenosine + H2O = D-ribose + adenine. GO:0047621 acylpyruvate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047621 EC:3.7.1.5|RHEA:19009|MetaCyc:ACYLPYRUVATE-HYDROLASE-RXN|UM-BBD_reactionID:r1401 3-acylpyruvate acylhydrolase activity Catalysis of the reaction: a 3-acylpyruvate + H2O = a carboxylate + pyruvate. CHEBI:83027 16beta-hydroxytestosterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83027 GO:0047620 acylglycerol kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047620 MetaCyc:ACYLGLYCEROL-KINASE-RXN|EC:2.7.1.94|RHEA:19293|Reactome:R-HSA-5696074 monoglyceride phosphokinase activity|monoacylglycerol kinase (phosphorylating)|monoacylglycerol kinase activity|monoglyceride kinase activity|ATP:acylglycerol 3-phosphotransferase activity|MGK|sn-2-monoacylglycerol kinase activity Catalysis of the reaction: ATP + acylglycerol = ADP + acyl-sn-glycerol 3-phosphate. CHEBI:24693 hydroxycyclohexanone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24693 UBERON:0001460 arm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001460 brachium|upper extremity The part of the forelimb extending from the shoulder to the autopod[cjm]. CHEBI:10022 deoxynivalenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_10022 GO:0047629 ADP deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047629 EC:3.5.4.7|RHEA:12741|MetaCyc:ADP-DEAMINASE-RXN adenosinepyrophosphate deaminase activity|adenosine diphosphate deaminase activity|ADP aminohydrolase activity Catalysis of the reaction: ADP + H2O = IDP + NH3. GO:0047628 ADP-thymidine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047628 RHEA:13413|EC:2.7.1.118|MetaCyc:ADP--THYMIDINE-KINASE-RXN ADP:dThd phosphotransferase activity|adenosine diphosphate-thymidine phosphotransferase activity|ADP:thymidine 5'-phosphotransferase activity Catalysis of the reaction: ADP + thymidine = AMP + thymidine 5'-phosphate. GO:0047627 adenylylsulfatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047627 KEGG_REACTION:R00531|EC:3.6.2.1|RHEA:17041|MetaCyc:ADENYLYLSULFATASE-RXN adenylylsulphatase activity|adenylylsulfate sulfohydrolase activity|adenosine 5-phosphosulfate sulfohydrolase activity Catalysis of the reaction: 5'-adenylyl sulfate + H(2)O = AMP + 2 H(+) + sulfate. GO:0047626 adenosylmethionine hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047626 RHEA:14645|KEGG_REACTION:R00175|EC:3.3.1.2|MetaCyc:ADENOSYLMETHIONINE-HYDROLASE-RXN S-adenosyl-L-methionine hydrolase activity|adenosylmethionine lyase activity|S-adenosylmethionine cleaving enzyme activity|methylmethionine-sulfonium-salt hydrolase activity|adenosyl methionine hydrolase activity Catalysis of the reaction: S-adenosyl-L-methionine + H(2)O = S-methyl-5'-thioadenosine + L-homoserine + H(+). UBERON:0001466 pedal digit biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001466 pes digit|toe|hind_digit|hind digit|digitus pedis|digit of foot|digit of terminal segment of lower limb|foot digit|pedal digit (phalangeal portion) plus soft tissue|digitipedis|hindlimb digit|digiti pedis|digiti pedis A digit that is part of a pes (foot). UBERON:0001465 knee biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001465 knee region A segment of the hindlimb that corresponds to the joint connecting a hindlimb stylopod and zeugopod. UBERON:0001467 shoulder biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001467 articulatio humeri|shoulder region A subdivision of the pectoral complex consisting of the structures in the region of the shoulder joint (which connects the humerus, scapula and clavicle). UBERON:0001461 elbow biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001461 elbow limb segment|articulatio cubiti|elbow region|cubital region The elbow is the region surrounding the elbow-joint-the ginglymus or hinge joint in the middle of the arm. Three bones form the elbow joint: the humerus of the upper arm, and the paired radius and ulna of the forearm. The bony prominence at the very tip of the elbow is the olecranon process of the ulna, and the inner aspect of the elbow is called the antecubital fossa. [WP,unvetted,human-specific]. UBERON:0001464 hip biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001464 regio coxae|hip region|coxa The hip region is located lateral to the gluteal region (i.e. the buttock), inferior to the iliac crest, and overlying the greater trochanter of the thigh bone. In adults, three of the bones of the pelvis have fused into the hip bone which forms part of the hip region. The hip joint, scientifically referred to as the acetabulofemoral joint (art. coxae), is the joint between the femur and acetabulum of the pelvis and its primary function is to support the weight of the body in both static (e.g. standing) and dynamic (e.g. walking or running) postures. [WP,modified]. CHEBI:24663 hydroxy-5beta-cholanic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24663 CHEBI:24662 hydroxy-amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24662 CHEBI:24669 hydroxy carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24669 UBERON:0001448 metatarsal bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001448 ossa metatarsi|ossa metatarsalia|metatarsal The metatarsus or metatarsal bones are a group of five long bones in the pes located between the tarsal bones of the hind- and mid-pes and the phalanges of the toes. Lacking individual names, the metatarsal bones are numbered from the medial side (side of big toe): the first, second, third, fourth, and fifth metatarsal. The metatarsals are analogous to the metacarpal bones of the manus. [WP,unvetted]. UBERON:0001447 tarsal bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001447 bony tarsus|ossa tarsi|ankle bone|bone of ankle|bone of tarsal skeleton|tarsus osseus|ossa tarsalia|bone of tarsus|hind mesopodium|tarsal A bone that is part of the tarsal skeleton. Examples: calcaneus, talus, centralia. CHEBI:48635 fumagillin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48635 CHEBI:24668 hydroxyacetophenone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24668 CHEBI:48638 5'-phospho-(3'->5')-dinucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48638 UBERON:0001449 phalanx of pes biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001449 toe phalanx|phalanges of hind digit|phalanx of pes|phalanx of foot digit|digitus pedis phalanx|foot digit phalanx|pedal phalanx|digital bone of pes|phalanx of toe|bone of toe|foot phalanx|phalanx of hind digit|phalanx of digit of foot|phalanx of digitus pedis A phalanx that is part of a hindlimb autopod[Automatically generated definition]. CHEBI:48637 (3'->5')-dinucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48637 GO:0047636 alanopine dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047636 MetaCyc:ALANOPINE-DEHYDROGENASE-RXN|EC:1.5.1.17|KEGG_REACTION:R00398|RHEA:17589 ADH|meso-N-(1-carboxyethyl)-alanine:NAD+ oxidoreductase activity|alanopine: NAD oxidoreductase activity|alanopine[meso-N-(1-carboxyethyl)-alanine]dehydrogenase activity|alanopine:NAD oxidoreductase activity|2,2'-iminodipropanoate:NAD+ oxidoreductase (L-alanine-forming)|ALPDH Catalysis of the reaction: 2,2'-iminodipropanoate + H(2)O + NAD(+) = L-alanine + H(+) + NADH + pyruvate. GO:0047635 alanine-oxo-acid transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047635 MetaCyc:ALANINE--OXO-ACID-AMINOTRANSFERASE-RXN|EC:2.6.1.12|RHEA:19953 alanine-oxo acid aminotransferase activity|L-alanine-alpha-keto acid aminotransferase activity|L-alanine:2-oxo-acid aminotransferase activity|alanine--oxo-acid aminotransferase activity|alanine-oxo-acid aminotransferase activity|leucine-alanine transaminase activity|alanine-keto acid aminotransferase activity Catalysis of the reaction: L-alanine + a 2-oxo acid = pyruvate + an L-amino acid. GO:0047634 agmatine N4-coumaroyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047634 KEGG_REACTION:R01617|RHEA:13405|EC:2.3.1.64|MetaCyc:AGMATINE-N4-COUMAROYLTRANSFERASE-RXN 4-coumaroyl-CoA:agmatine 4-N-coumaroyltransferase activity|agmatine coumaroyltransferase activity|p-coumaroyl-CoA-agmatine N-p-coumaroyltransferase activity|4-coumaroyl-CoA:agmatine N4-coumaroyltransferase activity Catalysis of the reaction: 4-coumaroyl-CoA + agmatine = N-(4-guanidiniumylbutyl)-4-hydroxycinnamamide + CoA + H(+). GO:0047633 agmatine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047633 MetaCyc:AGMATINE-KINASE-RXN|KEGG_REACTION:R01417|RHEA:15953|EC:2.7.3.10 ATP:agmatine N4-phosphotransferase activity|phosphagen phosphokinase activity|ATP:agmatine 4-N-phosphotransferase activity Catalysis of the reaction: agmatine + ATP = N(4)-phosphoagmatine + ADP + 3 H(+). GO:0047632 agmatine deiminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047632 MetaCyc:AGMATINE-DEIMINASE-RXN|EC:3.5.3.12|RHEA:18037 agmatine amidinohydrolase|agmatine iminohydrolase activity Catalysis of the reaction: agmatine + H2O = N-carbamoylputrescine + NH3. CHEBI:83039 crustacean metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83039 CHEBI:24661 hydroxy-L-lysine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24661 GO:0047631 ADP-ribose diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047631 Reactome:R-HSA-5696049|MetaCyc:RXN0-1441|Reactome:R-HSA-2393939|EC:3.6.1.13|RHEA:10412|Reactome:R-HSA-2393954 ADP-ribose pyrophosphatase activity|adenosine diphosphoribose pyrophosphatase activity|ADP-ribose phosphohydrolase activity|ADPribose pyrophosphatase activity|ADPR-PPase activity|ADPribose diphosphatase activity|ADP-ribose ribophosphohydrolase activity Catalysis of the reaction: ADP-ribose + H2O = AMP + D-ribose 5-phosphate. CHEBI:83038 Daphnia galeata metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83038 GO:0047630 ADP-phosphoglycerate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047630 EC:3.1.3.28|KEGG_REACTION:R03969|MetaCyc:ADP-PHOSPHOGLYCERATE-PHOSPHATASE-RXN|RHEA:15861 ADPphosphoglycerate phosphatase activity|adenosine diphosphate phosphoglycerate phosphatase activity|3-(ADP)-2-phosphoglycerate phosphohydrolase activity Catalysis of the reaction: 3-ADP-2-phosphoglycerate + H(2)O = 3-ADP-glycerate + phosphate. CHEBI:83032 4-O-beta-D-glucosyl-trans-4-coumaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83032 GO:0047639 alcohol oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047639 MetaCyc:ALCOHOL-OXIDASE-RXN|EC:1.1.3.13|RHEA:19829 AOX activity|ethanol oxidase activity|alcohol:oxygen oxidoreductase activity Catalysis of the reaction: a primary alcohol + O2 = an aldehyde + H2O2. GO:0047638 albendazole monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047638 EC:1.14.13.32|MetaCyc:ALBENDAZOLE-MONOOXYGENASE-RXN|KEGG_REACTION:R03712|RHEA:10796 albendazole,NADPH:oxygen oxidoreductase (sulfoxide-forming)|albendazole oxidase activity|albendazole sulfoxidase activity Catalysis of the reaction: albendazole + H(+) + NADPH + O(2) = albendazole S-oxide + H(2)O + NADP(+). GO:0047637 alanylphosphatidylglycerol synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047637 MetaCyc:ALANYLPHOSPHATIDYLGLYCEROL-SYNTHASE-RXN|EC:2.3.2.11|RHEA:20489 L-alanyl-tRNA:phosphatidylglycerol alanyltransferase activity|O-alanylphosphatidylglycerol synthase activity|alanyl phosphatidylglycerol synthetase activity Catalysis of the reaction: L-alanyl-tRNA + phosphatidylglycerol = tRNA + 3-O-L-alanyl-1-O-phosphatidylglycerol. UBERON:0001457 skin of eyelid biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001457 eyelid zone of skin|zone of skin of eyelid|blepharon zone of skin|zone of skin of blepharon|eyelid skin A zone of skin that is part of a eyelid [Automatically generated definition]. UBERON:0001456 face biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001456 visage|facia/facies A subdivision of the head that has as parts the layers deep to the surface of the anterior surface, including the mouth, eyes, and nose (when present). In vertebrates, this includes the facial skeleton and structures superficial to the facial skeleton (cheeks, mouth, eyeballs, skin of face, etc). CHEBI:24676 hydroxybenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24676 CHEBI:48621 Sep-tRNA(Sec) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48621 CHEBI:24675 hydroxybenzoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24675 CHEBI:24673 hydroxybenzaldehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24673 CHEBI:48622 pGpG biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48622 UBERON:0001437 epiphysis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001437 long bone epiphysis|epiphyses|bone epiphysis|end of long bone The head of a long bone that articulates with a neighboring skeletal element and is separated from the shaft by the epiphyseal plate until bone growth stops. At that time, the plate disappears and the head and shaft are united[MESH,modified]. UBERON:0001436 phalanx of manus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001436 phalanx of hand|phalanx of fore digit|phalanx of finger|hand phalanx|phalanx of digit of hand|phalanx of digitus manus|phalanges of fore digit|bone of finger|finger phalanx|manual phalanx|phalanx of hand digit|digitus manus phalanx|digital bone of manus|hand digit phalanx|phalanx of manual digit A phalanx that is part of a forelimb autopod[Automatically generated definition]. CHEBI:24679 hydroxybenzyl alcohol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24679 CHEBI:24678 hydroxybenzoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24678 UBERON:0001438 metaphysis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001438 diaphyseal end of long bone|long bone metaphysis|metaphyses Zone of long bone that is between the epiphysis and diaphysis. Subdivision of diaphysis which forms the proximal or distal end of diaphysis next to the epiphysis; together with diaphysis proper, it constitutes the diaphysis. Examples: proximal metaphysis of humerus, distal metaphysis of femur.[FMA] CHEBI:24677 hydroxybenzophenone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24677 CHEBI:48626 pyranoindolizinoquinoline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48626 GO:0047647 alkylacetylglycerophosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047647 KEGG_REACTION:R03454|RHEA:18221|MetaCyc:ALKYLACETYLGLYCEROPHOSPHATASE-RXN|EC:3.1.3.59 1-alkyl-2-acetyl-sn-glycero-3-phosphate phosphohydrolase activity|1-alkyl-2-lyso-sn-glycero-3-P:acetyl-CoA acetyltransferase activity|alkylacetylglycerophosphate phosphatase activity Catalysis of the reaction: 1-alkyl-2-acetyl-sn-glycerol 3-phosphate + H(2)O = 2-acetyl-1-alkyl-sn-glycerol + phosphate. GO:0047646 alkanal monooxygenase (FMN-linked) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047646 MetaCyc:ALKANAL-MONOOXYGENASE-FMN-LINKED-RXN|RHEA:17181|EC:1.14.14.3 aldehyde monooxygenase activity|alkanal,reduced-FMN:oxygen oxidoreductase (1-hydroxylating, luminescing)|bacterial luciferase activity|vibrio fischeri luciferase activity Catalysis of the reaction: R-CHO + reduced FMN + O2 = R-COOH + FMN + H2O + light. GO:0047645 alkan-1-ol dehydrogenase (acceptor) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047645 RHEA:14685|MetaCyc:ALKAN-1-OL-DEHYDROGENASE-ACCEPTOR-RXN|EC:1.1.99.20 polyethylene glycol dehydrogenase activity|alkan-1-ol:(acceptor) oxidoreductase activity|alkan-1-ol:acceptor oxidoreductase activity Catalysis of the reaction: primary alcohol + acceptor = aldehyde + reduced acceptor. GO:0047644 alizarin 2-beta-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047644 KEGG_REACTION:R03573|EC:2.4.1.103|MetaCyc:ALIZARIN-2-BETA-GLUCOSYLTRANSFERASE-RXN|RHEA:20677 uridine diphosphoglucose-alizarin glucosyltransferase activity|UDP-glucose:1,2-dihydroxy-9,10-anthraquinone 2-O-beta-D-glucosyltransferase activity|alizarin 2-b-glucosyltransferase activity|UDPglucose:1,2-dihydroxy-9,10-anthraquinone 2-O-beta-D-glucosyl-transferase activity Catalysis of the reaction: alizarin + UDP-D-glucose = 1-hydroxy-2-(beta-D-glucosyloxy)-9,10-anthraquinone + H(+) + UDP. PR:000009345 kit ligand biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000009345 stem cell factor|SCF|Sl|hematopoietic growth factor KL|Kitl|mast cell growth factor|KITLG|Slf|steel factor|MGF|c-Kit ligand A protein that is a translation product of the human KITLG gene or a 1:1 ortholog thereof. GO:0047643 alginate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047643 MetaCyc:ALGINATE-SYNTHASE-RXN|EC:2.4.1.33|RHEA:46876 GDP-D-mannuronate:alginate D-mannuronyltransferase activity|mannuronosyl transferase activity Catalysis of the reaction: GDP-D-mannuronate + alginate(n) = GDP + alginate(n+1). GO:0047642 aldose beta-D-fructosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047642 EC:2.4.1.162|MetaCyc:ALDOSE-BETA-FRUCTOSYLTRANSFERASE-RXN aldose b-D-fructosyltransferase activity|alpha-D-aldosyl-beta-D-fructoside:aldose 1-beta-D-fructosyltransferase activity Catalysis of the reaction: alpha-D-aldosyl1 beta-D-fructoside + D-aldose2 = D-aldose1 + alpha-D-aldosyl2 beta-D-fructoside. GO:0047641 aldose-6-phosphate reductase (NADPH) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047641 EC:1.1.1.200|MetaCyc:ALDOSE-6-PHOSPHATE-REDUCTASE-NADPH-RXN|KEGG_REACTION:R00834|RHEA:20037 D-aldose-6-phosphate:NADP+ 1-oxidoreductase activity|aldose-6-P reductase activity|A6PR|NADP-dependent D-sorbitol-6-phosphate dehydrogenase activity|NADP-dependent aldose 6-phosphate reductase activity|alditol 6-phosphate:NADP 1-oxidoreductase activity|aldose-6-phosphate reductase activity|aldose 6-phosphate reductase activity Catalysis of the reaction: D-glucitol 6-phosphate + NADP(+) = D-glucose 6-phosphate + H(+) + NADPH. CHEBI:83048 4,4'-diaponeurosporenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83048 GO:0047640 aldose 1-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047640 MetaCyc:ALDOSE-1-DEHYDROGENASE-RXN|EC:1.1.1.121|RHEA:15917 aldose dehydrogenase activity|dehydrogenase, D-aldohexose|D-aldose:NAD+ 1-oxidoreductase activity Catalysis of the reaction: D-aldose + NAD+ = D-aldonolactone + NADH. CHEBI:83047 1-stearoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83047 CHEBI:83045 dodecenoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83045 CHEBI:10043 wogonin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_10043 CHEBI:83043 4,4'-diapolycopenedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83043 CHEBI:83042 undecenoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83042 CHEBI:10049 XTP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_10049 GO:0047649 alkylglycerol kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047649 KEGG_REACTION:R04126|EC:2.7.1.93|MetaCyc:ALKYLGLYCEROL-KINASE-RXN|RHEA:16937 ATP:1-O-alkyl-sn-glycerol 3-phosphotransferase activity|1-alkylglycerol kinase (phosphorylating)|ATP-alkylglycerol phosphotransferase activity|ATP:1-alkyl-sn-glycerol phosphotransferase activity|alkylglycerol phosphotransferase activity Catalysis of the reaction: 1-alkyl-sn-glycerol + ATP = 1-alkyl-sn-glycerol 3-phosphate + ADP + 2 H(+). CHEBI:10048 XDP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_10048 GO:0047648 alkylamidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047648 KEGG_REACTION:R03620|MetaCyc:ALKYLAMIDASE-RXN|RHEA:20081|EC:3.5.1.39 N-methylhexanamide amidohydrolase activity Catalysis of the reaction: N-methylhexanamide + H(2)O = hexanoate + methylammonium. UBERON:0001444 subdivision of head biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001444 head region|head subdivision|region of head UBERON:0001443 chest biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001443 anterolateral part of thorax|ventral part of thoracic region|thorax|pectus|front of thorax|thoracic body wall Subdivision of trunk proper, which is demarcated from the neck by the plane of the superior thoracic aperture and from the abdomen internally by the inferior surface of the diaphragm and externally by the costal margin and associated with the thoracic vertebral column and ribcage and from the back of the thorax by the external surface of the posterolateral part of the rib cage, the anterior surface of the thoracic vertebral column and the posterior axillary lines; together with the abdomen and the perineum, it constitutes the trunk proper[FMA]. UBERON:0001446 fibula biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001446 The major postaxial endochondral bone in the posterior zeugopod[Phenoscape]. UBERON:0001445 skeleton of pes biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001445 pes skeleton|posterior autopodium|foot region skeleton|skeleton of foot|posterior autopodium skeleton|foot skeleton|set of bones of foot|pes|pedal skeleton Subdivision of skeleton that is the collection of all skeletal elements in a pes, which is the distal section of the posterior hindlimb skeleton consisting of the mesopodium, the metapodium and the acropodium (e.g. including the ankle, sole, and toes)[Phenoscape]. UBERON:0001440 forelimb skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001440 skeleton of free upper limb|free upper limb skeleton|ossa membri superioris|skeleton of pectoral limb|bones of upper limb|wing skeleton|skeleton of upper limb|skeleton of forelimb|forelimb skeleton|set of bones of upper limb|upper limb skeleton|fore limb skeleton|pectoral limb skeleton The collection of all skeletal elements in a free forelimb region. Excludes the pectoral girdle UBERON:0001442 skeleton of manus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001442 anterior autopodium|ossa manus|forelimb autopod skeleton|hand region skeleton|manual skeleton|bones of hand|skeleton of hand|hand skeleton|set of bones of hand|fore autopod skeleton|anterior autopodium skeleton|manus skeleton|manus Subdivision of skeleton that is the collection of all skeletal elements in a manus, which is the distal section of the anterior forelimb skeleton consisting of the mesopodium, the metapodium and the acropodium (e.g. including the wrist, palm, and fingers)[Phenoscape]. UBERON:0001441 hindlimb skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001441 skeleton of free lower limb|bones of lower limb|free lower limb skeleton|skeleton of lower limb|hind-limb skeleton|hindlimb skeleton|set of bones of lower limb|lower limb skeleton|ossa membri inferioris|hind limb skeleton Subdivision of skeleton consisting of all skeletal elements in an hindlimb region. GO:0033009 nucleomorph biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033009 Wikipedia:Nucleomorph A small, vestigial nucleus found in some plastids that derive from a eukaryotic endosymbiont. Observed in chlorarachniophytes and cryptomonads, which acquired their plastids from a green and red alga respectively. GO:0033008 positive regulation of mast cell activation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033008 positive regulation of mast cell activation during immune response Any process that activates or increases the frequency, rate, or extent of mast cell activation as part of an immune response. GO:0033007 negative regulation of mast cell activation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033007 negative regulation of mast cell activation during immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell activation as part of an immune response. GO:0008049 male courtship behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008049 male courtship behaviour The behavior of a male, for the purpose of attracting a sexual partner. An example of this process is found in Drosophila melanogaster. GO:0008048 calcium sensitive guanylate cyclase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008048 Binds to and increases the activity of guanylate cyclase in response to a change in calcium ion concentration. GO:0008047 enzyme activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008047 metalloenzyme activator activity Binds to and increases the activity of an enzyme. GO:0008046 axon guidance receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008046 receptor activity involved in axon guidance Combining with an extracellular messenger and transmitting the signal from one side of the membrane to the other to results in a change in cellular activity involved in axon guidance. GO:0008045 motor neuron axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008045 motoneuron axon guidance|motor axon pathfinding|motor axon guidance The process in which the migration of an axon growth cone of a motor neuron is directed to a specific target site in response to a combination of attractive and repulsive cues. GO:0008044 obsolete adult behavior (sensu Insecta) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008044 adult behavior (sensu Insecta) OBSOLETE. Behavior in a fully developed and mature organism, as seen in insects. GO:0008043 intracellular ferritin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0008043 A ferritin complex located in the cell. Intracellular ferritin complexes contain 24 subunits, in a mixture of L (light) chains and H (heavy) chains. GO:0008053 mitochondrial fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008053 Merging of two or more mitochondria within a cell to form a single compartment. GO:0008052 sensory organ boundary specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008052 sense organ boundary specification The process in which boundaries between a sensory organ and the surrounding tissue are established and maintained. CHEBI:58099 dTDP-6-deoxy-L-talose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58099 GO:0008051 obsolete farnesyl-diphosphate farnesyl transferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0008051 farnesyl-diphosphate farnesyl transferase complex OBSOLETE. A complex that possesses farnesyl-diphosphate farnesyl transferase activity. GO:0008050 female courtship behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008050 female courtship behaviour The behavior of a female, for the purpose of attracting a sexual partner. CHEBI:58098 2-dehydro-3-deoxy-D-glucarate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58098 CHEBI:58097 morphine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58097 CHEBI:58096 dolichyl D-xylosyl phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58096 CHEBI:58095 L-phenylalanine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58095 GO:0033006 regulation of mast cell activation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033006 regulation of mast cell activation during immune response Any process that modulates the frequency, rate, or extent of mast cell activation as part of an immune response. GO:0033005 positive regulation of mast cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033005 Any process that activates or increases the frequency, rate, or extent of mast cell activation. GO:0033004 negative regulation of mast cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033004 Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell activation. GO:0033003 regulation of mast cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033003 Any process that modulates the frequency, rate, or extent of mast cell activation. GO:0033002 muscle cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033002 myocyte proliferation The expansion of a muscle cell population by cell division. GO:0033001 Fc-gamma receptor III complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033001 immunoglobulin G receptor complex|IgG receptor complex|FcgRIII complex A protein complex composed of an Fc-gamma RIII alpha chain and an Fc-epsilon RI gamma chain dimer with or without an Fc-epsilon RI beta chain and additional signaling components. The complex functions primarily as an activating receptor for IgG. GO:0033000 Fc-gamma receptor I complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033000 immunoglobulin G receptor complex|IgG receptor complex|FcgRI complex A protein complex composed of an Fc-gamma RI alpha chain and an Fc-epsilon RI gamma chain dimer with or without additional signaling components. The complex functions primarily as an activating receptor for IgG. CHEBI:58093 homoserinium lactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58093 CHEBI:58092 N-phosphocreatinate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58092 GO:0008059 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008059 CHEBI:58091 deacetylisoipecoside(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58091 GO:0008058 ocellus pigment granule organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008058 ocellus pigment granule organization and biogenesis|ocellus pigment granule organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of intracellular pigment storage granules in the ocellus. CHEBI:58090 L-cysteate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58090 GO:0008057 eye pigment granule organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008057 eye pigment granule organization and biogenesis|eye pigment granule organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of intracellular pigment storage granules in the eye. GO:0008056 ocellus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008056 The process whose specific outcome is the progression of the ocellus over time, from its formation to the mature structure. The ocellus is a simple visual organ of insects. GO:0008055 ocellus pigment biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008055 ocellus pigment anabolism|ocellus pigment biosynthesis|ocellus pigment synthesis|ocellus pigment formation The chemical reactions and pathways resulting in the formation of ocellus pigments, any general or particular coloring matter in living organisms, found or utilized in the ocellus, a minute simple eye found in many invertebrates. GO:0008054 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008054 GO:0008064 regulation of actin polymerization or depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008064 Any process that modulates the frequency, rate or extent of the assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament. GO:0008063 Toll signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008063 Toll signalling pathway|Tl signaling pathway|Tl signalling pathway A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Toll on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. CHEBI:58089 5-phosphonato-D-ribosylaminium(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58089 CHEBI:58088 1-phosphatidyl-1D-myo-inositol 3-phosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58088 GO:0008062 eclosion rhythm biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008062 The timing of the emergence of the adult fly from its pupal case, which usually occurs at dawn. CHEBI:58087 N-(3-carboxylatopropionyl)-LL-2,6-diaminopimelate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58087 GO:0008061 chitin binding biolink:MolecularActivity go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0008061 Interacting selectively and non-covalently with chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues. GO:0008060 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008060 CHEBI:58086 UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58086 CHEBI:58085 2-isopropylmaleate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58085 CHEBI:58083 glycerol 2-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58083 GO:0008029 pentraxin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008029 pentaxin receptor Combining with a pentraxin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0008028 monocarboxylic acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008028 Reactome:R-HSA-5624211|Reactome:R-HSA-429749|Reactome:R-HSA-9645220|Reactome:R-HSA-433698 monocarboxylate carrier|prostaglandin/thromboxane transporter activity Enables the transfer of monocarboxylic acids from one side of a membrane to the other. A monocarboxylic acid is an organic acid with one COOH group. CHEBI:58082 O-(1->4)-alpha-L-dihydrostreptosylstreptidine 6-phosphate zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58082 CHEBI:58081 dTDP-D-galacturonate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58081 GO:0008027 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008027 GO:0008026 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008026 CHEBI:58080 N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58080 GO:0008025 obsolete diazepam binding inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008025 DBI|diazepam binding inhibitor activity|diazepam-binding inhibitor activity OBSOLETE. The diazepam binding inhibitor is a 10kDa 86-residue polypeptide that acts as an endogenous ligand for a mitochondrial receptor (formerly regarded as a peripheral benzodiazepine binding site) in steroidogenic cells and regulates stimulation of steroidogenesis by tropic hormones. It also binds to the GABA-A receptor and modulates glucose-dependent insulin secretion and synthesis of acyl-CoA esters. GO:0008024 cyclin/CDK positive transcription elongation factor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0008024 positive transcription elongation factor complex b A transcription elongation factor complex that facilitates the transition from abortive to productive elongation by phosphorylating the CTD domain of the large subunit of DNA-directed RNA polymerase II, holoenzyme. Contains a cyclin and a cyclin-dependent protein kinase catalytic subunit. GO:0008023 transcription elongation factor complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0008023 Any protein complex that interacts with RNA polymerase II to increase (positive transcription elongation factor) or reduce (negative transcription elongation factor) the rate of transcription elongation. GO:0008022 protein C-terminus binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0008022 carboxy-terminus binding|carboxylate-terminal binding|carboxyl-terminal binding|carboxylate-terminus binding|carboxyl-terminus binding|C-terminal binding|COOH-terminus binding|COOH-terminal binding|C-terminal end binding|carboxy-terminal binding Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxyl function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue. GO:0008021 synaptic vesicle biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0008021 Wikipedia:Synaptic_vesicle|NIF_Subcellular:sao1071221672 docked vesicle A secretory organelle, typically 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane. CHEBI:58079 butanoyl phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58079 GO:0008031 eclosion hormone activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008031 The action characteristic of eclosion hormone, a peptide hormone that, upon receptor binding, triggers the death of certain muscles and neurons during insect metamorphosis. GO:0008030 neuronal pentraxin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008030 neuronal pentaxin receptor Combining with a neuronal pentraxin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. CHEBI:58078 CDP-3,6-dideoxy-D-mannose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58078 CHEBI:58077 bis-gamma-glutamylcystinate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58077 CHEBI:58075 2-hydroxy-4-oxobutane-1,2,4-tricarboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58075 CHEBI:58074 D-nopalinate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58074 CHEBI:58072 carbon monoxide(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58072 CHEBI:73603 7-(2-hydroxy-3-amino-3-carboxypropyl)wyosine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73603 CHEBI:58071 mono(2-ethylhexyl) phthalate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58071 GO:0008039 synaptic target recognition biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0008039 neuronal targeting The process in which a neuronal cell in a multicellular organism interprets signals produced by potential target cells, with which it may form synapses. CHEBI:58070 dehydroascorbide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58070 GO:0008038 neuron recognition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008038 neuronal cell recognition The process in which a neuronal cell in a multicellular organism interprets its surroundings. GO:0008037 cell recognition biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0008037 recognition of surroundings by cell The process in which a cell in an organism interprets its surroundings. GO:0008036 diuretic hormone receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008036 Combining with a diuretic hormone and transmitting the signal to initiate a change in cell activity. GO:0008035 high-density lipoprotein particle binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008035 HDL binding Interacting selectively and non-covalently with high-density lipoprotein particle, a lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE. GO:0008034 obsolete lipoprotein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008034 lipoprotein binding OBSOLETE. Interacting selectively and non-covalently with any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids. UBERON:3010706 lateral line nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_3010706 GO:0008033 tRNA processing biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0008033 tRNA maturation The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group. GO:0008032 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008032 GO:0008042 obsolete iron-sulfur electron transfer carrier biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008042 iron-sulfur electron transfer carrier|iron-sulphur electron transfer carrier|ferredoxin OBSOLETE. An iron-sulfur protein that serves as an electron acceptor and electron donor in an electron transport system. CHEBI:58068 2-hydroxy-6-oxohexa-2,4-dienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58068 CHEBI:58067 (3Z,5S)-3-(1-oxidoethylidene)-5-{[4-(3-methylbut-2-en-1-yl)-1H-indol-3-yl]methyl}pyrrolidine-2,4-dione(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58067 GO:0008041 obsolete storage protein of fat body (sensu Insecta) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008041 storage protein of fat body (sensu Insecta) OBSOLETE. (Was not defined before being made obsolete). GO:0008040 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008040 CHEBI:58066 L-glutamic 5-semialdehyde zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58066 CHEBI:58065 homocysteine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58065 CHEBI:58064 taurocyamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58064 CHEBI:58062 rosmarinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58062 CHEBI:58061 salutaridinium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58061 DDANAT:0010001 Dictyostelium discoideum anatomical structure biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0010001 Material anatomical entity that has inherent 3D shape and is generated by coordinated expression of the Dictyostelium discoideum genome. CHEBI:58069 CDP(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58069 CHEBI:73610 Met-Ala biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73610 GO:0008009 chemokine activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0008009 The function of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria. GO:0008008 obsolete membrane attack complex protein beta2 chain biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0008008 membrane attack complex protein beta2 chain OBSOLETE. (Was not defined before being made obsolete). GO:0008007 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008007 GO:0008006 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008006 GO:0008005 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008005 GO:0008004 obsolete lamina reticularis biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0008004 OBSOLETE. A layer of the basal lamina that contains collagen fibrils and connects the basal lamina to the underlying connective tissue. CHEBI:73619 3-methylthioaspartic acid residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73619 GO:0008003 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008003 GO:0008002 obsolete lamina lucida biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0008002 Wikipedia:Lamina_lucida OBSOLETE. The electron-lucent layer of the basal lamina adjacent to the basal plasma membrane of the cells that rest on the lamina. GO:0008001 obsolete fibrinogen biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008001 fibrinogen OBSOLETE. (Was not defined before being made obsolete). CHEBI:58057 geranyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58057 CHEBI:58056 2-methylideneglutarate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58056 CHEBI:58055 4,5-dioxopentanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58055 CHEBI:58053 IMP(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58053 CHEBI:58052 UDP-alpha-D-glucuronate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58052 CHEBI:58051 4,5-dihydroxyphthalate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58051 CHEBI:58050 dolichyl N-acetyl-alpha-D-glucosaminyl phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58050 CHEBI:34083 {1-hexadecanoyl-2-[(Z)-octadec-9-enoyl]-sn-glycero-3-phospho}ethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_34083 CHEBI:34086 {1-O-hexadecanoyl-2-O-[(Z)-octadec-9-enoyl]-sn-glycero-3-phospho}serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_34086 CHEBI:58059 oxidized Cypridina luciferin(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58059 CHEBI:58058 D-lysopine dizwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58058 CHEBI:73621 3-methylthioaspartic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73621 CHEBI:73620 3-methylthioaspartate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73620 CHEBI:73625 7-(2-hydroxy-3-amino-3-carboxypropyl)wyosine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73625 CHEBI:73624 7-(2-hydroxy-3-amino-3-carboxypropyl)wyosine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73624 GO:0008019 obsolete macrophage receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008019 macrophage receptor activity OBSOLETE. (Was not defined before being made obsolete). GO:0008018 obsolete structural protein of chorion (sensu Drosophila) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008018 structural protein of chorion (sensu Drosophila) OBSOLETE. (Was not defined before being made obsolete). CHEBI:73626 7-(2-hydroxy-3-amino-3-carboxypropyl)wyosine 5'-monophosphate zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73626 GO:0008017 microtubule binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008017 Reactome:R-HSA-9614343 microtubule/chromatin interaction|microtubule severing activity Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers. GO:0008016 regulation of heart contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008016 regulation of cardiac contraction Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body. GO:0008015 blood circulation biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0008015 hemolymph circulation The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products. GO:0008014 obsolete calcium-dependent cell adhesion molecule activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008014 calcium-dependent cell adhesion molecule activity|cadherin OBSOLETE. A calcium-dependent cell adhesion protein (type I membrane protein) that interacts in a homophilic manner in cell-cell interactions. GO:0008013 beta-catenin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008013 Interacting selectively and non-covalently with the beta subunit of the catenin complex. GO:0008012 structural constituent of adult chitin-based cuticle biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008012 structural constituent of adult cuticle The action of a molecule that contributes to the structural integrity of the chitin-based cuticle of an adult organism. An example of this is found in Drosophila melanogaster. GO:0008011 structural constituent of pupal chitin-based cuticle biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008011 structural constituent of pupal cuticle The action of a molecule that contributes to the structural integrity of the chitin-based cuticle of a pupa. An example of this is found in Drosophila melanogaster. GO:0008010 structural constituent of chitin-based larval cuticle biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008010 structural constituent of larval cuticle The action of a molecule that contributes to the structural integrity of the chitin-based cuticle of a larva. An example of this is found in Drosophila melanogaster. GO:0008020 G protein-coupled photoreceptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008020 G protein coupled photoreceptor activity|G-protein coupled photoreceptor activity|photoreceptor activity, G-protein coupled Combining with incidental electromagnetic radiation, particularly visible light, and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. CHEBI:58046 3,5-dibromo-4-oxidobenzonitrile(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58046 CHEBI:58045 L-isoleucine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58045 CHEBI:58044 2,5-dihydroxybenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58044 CHEBI:58043 nucleoside 5'-monophosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58043 CHEBI:58042 guanidinoethyl methyl phosphate zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58042 CHEBI:143979 5'-end phospho-guanosine(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_143979 CHEBI:58041 heparosan N-sulfate L-iduronate polyanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58041 CHEBI:58040 dimethylaminium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58040 CHEBI:58048 L-asparagine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58048 CHEBI:58047 thiomorpholine-3-carboxylic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58047 CHEBI:58035 1D-3-ammmonio-1-guanidiniumyl-1,3-dideoxy-scyllo-inositol(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58035 CHEBI:58034 flavonol 3-O-(6-O-malonyl-beta-D-glucoside)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58034 CHEBI:58033 2-phosphonatoglycolate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58033 CHEBI:58032 anhydrotetracycline zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58032 CHEBI:58031 2-(3-amino-3-carboxypropyl)-L-histidine dizwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58031 CHEBI:58030 5-formyl-2-hydroxyhepta-2,4-dienedioate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58030 CHEBI:143966 (2S)-homocitric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_143966 CHEBI:58039 N-methylputrescinium(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58039 CHEBI:58038 Photinus luciferin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58038 CHEBI:34063 naphthalene-1,4-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_34063 CHEBI:58037 O-demethylpuromycin(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58037 CHEBI:34080 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_34080 CHEBI:58024 deoxylimonoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58024 CHEBI:58023 (3,5-diiodo-4-oxidophenyl)pyruvate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58023 CHEBI:58022 10-oxocaprate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58022 CHEBI:58021 glucotropeolin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58021 CHEBI:58020 2-aminoacrylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58020 CHEBI:34071 1-arachidonoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_34071 CHEBI:58029 cysteaminium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58029 CHEBI:58028 6-O-sulfonato-alpha-D-Glc-(1->6)-alpha-D-Glc-(1->6)-alpha-D-Glc-(1->3)-1-O-alkyl-2-O-acylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58028 CHEBI:58027 glyceraldehyde 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58027 CHEBI:58026 8-hydroxy-1,4-dioxo-1,4-dihydronaphthalen-2-olate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58026 CHEBI:58025 octopaminium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58025 GO:0072573 tolerance induction to lipopolysaccharide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072573 tolerance induction to LPS|tolerance induction to endotoxin Tolerance induction directed at lipopolysaccharide antigens. GO:0072572 poly-ADP-D-ribose binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0072572 pADPr binding|poly-ADP-ribose binding Interacting selectively and non-covalently with polymeric ADP-D-ribose, a polymer that is composed of poly-ADP-D-ribose units linked through 1,2-glycosidic bonds at the ribose ring. GO:0072571 mono-ADP-D-ribose binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0072571 mADPr binding|mono-ADP-ribose binding Interacting selectively and non-covalently with monomeric ADP-D-ribose, an ADP-aldose having ribose as the aldose fragment. GO:0072570 ADP-D-ribose binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0072570 ADP-ribose binding Interacting selectively and non-covalently with ADP-D-ribose, an ADP-aldose having ribose as the aldose fragment. GO:0106313 methylenetetrahydrofolate reductase NADPH activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106313 RHEA:19817 Catalysis of the reaction: 5-methyltetrahydrofolate + NADP + = 5,10-methylenetetrahydrofolate + NADPH + H+. GO:0106312 methylenetetrahydrofolate reductase NADH activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106312 RHEA:19821 Catalysis of the reaction: 5-methyltetrahydrofolate + NAD + = 5,10-methylenetetrahydrofolate + NADH + H+. GO:0106311 protein threonine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106311 RHEA:46608|EC:2.7.11.1 Catalysis of the reactions: ATP + protein threonine = ADP + threonine phosphate. GO:0106310 protein serine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106310 EC:2.7.11.1|RHEA:17989 Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate. GO:0106317 methane monooxygenase NADH activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106317 EC:1.14.13.25|RHEA:13637 Catalysis of the reaction: methane + NADH + H+ + O2 = methanol + NAD+ + H2O. UBERON:2001053 future internal carotid artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_2001053 PICA|primitive internal carotid artery GO:0106316 nitrite reductase NADH activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106316 RHEA:24628 Catalysis of the reaction: ammonium hydroxide + 3 NAD+ + H2O = nitrite + 3 NADH + 3 H+. GO:0106314 nitrite reductase NADPH activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106314 RHEA:24632 Catalysis of the reaction: ammonium hydroxide + 3 NADP+ + H2O = nitrite + 3 NADPH + 3 H+. GO:0106319 (R)-limonene 1,2-monooxygenase NADH activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106319 EC:1.14.13.107|RHEA:26093 Catalysis of the reaction: (4R)-limonene + NADH + H+ + O2 = NAD+ + H2O + (4R)-limonene-1,2-epoxide. GO:0106318 methane monooxygenase NADPH activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106318 EC:1.14.13.25|RHEA:13641 Catalysis of the reaction: methane + NADPH + H+ + O2 = methanol + NADP+ + H2O. GO:0072579 glycine receptor clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072579 The receptor clustering process in which glycine receptors are localized to distinct domains in the cell membrane. GO:0072578 neurotransmitter-gated ion channel clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072578 The receptor clustering process in which neurotransmitter-gated ion channels are localized to distinct domains in the cell membrane. GO:0072577 endothelial cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072577 programmed cell death of endothelial cells by apoptosis|killing of endothelial cells|endothelial cell programmed cell death by apoptosis|apoptosis of endothelial cells|endothelial cell apoptosis|programmed cell death, endothelial cells Any apoptotic process in an endothelial cell. An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. GO:0072576 liver morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072576 The process in which the anatomical structures of the liver are generated and organized. GO:0072575 epithelial cell proliferation involved in liver morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072575 The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the liver. GO:0072574 hepatocyte proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072574 The multiplication or reproduction of hepatocytes, resulting in the expansion of a cell population. Hepatocytes form the main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. GO:0106320 (R)-limonene 1,2-monooxygenase NADPH activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106320 RHEA:26097|EC:1.14.13.107 Catalysis of the reaction: (4R)-limonene + NADPH + H+ + O2 = NADP+ + H2O + (4R)-limonene-1,2-epoxide. GO:0072562 blood microparticle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0072562 cell membrane microparticle A phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell. Microparticles are heterogeneous in size, and are characterized as microvesicles free of nucleic acids. GO:0072561 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072561 GO:0072560 type B pancreatic cell maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072560 pancreatic beta cell maturation|pancreatic B cell maturation A developmental process, independent of morphogenetic (shape) change, that is required for a type B pancreatic cell to attain its fully functional state. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin. GO:0106324 (S)-limonene 1,2-monooxygenase NADH activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106324 RHEA:26089 Catalysis of the reaction: (4S)-limonene + NADH + H+ + O2 = NAD+ + H2O + (4S)-limonene-1,2-epoxide. GO:0106323 (S)-limonene 1,2-monooxygenase NADPH activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106323 RHEA:26085 Catalysis of the reaction: (4S)-limonene + NADPH+= + H+ + O2 = NADP+ + H2O + (4S)-limonene-1,2-epoxide. GO:0106322 S-(hydroxymethyl)glutathione dehydrogenase NAD activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106322 RHEA:19985|EC:1.1.1.284 Catalysis of the reaction: S-(hydroxymethyl)glutathione + NAD+ = S-formylglutathione + NADH + H+. GO:0106321 S-(hydroxymethyl)glutathione dehydrogenase NADP activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106321 RHEA:19981|EC:1.1.1.284 Catalysis of the reaction: S-(hydroxymethyl)glutathione + NADP+ = S-formylglutathione + NADPH + H+. GO:0106328 acetylgalactosaminyl-O-glycosyl-seryl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106328 RHEA:46884|EC:2.4.1.147 Catalysis of the reaction: 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + H(+) + UDP. GO:0106327 acetylgalactosaminyl-O-glycosyl-threonyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106327 RHEA:46880|EC:2.4.1.147 Catalysis of the reaction: 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + H(+) + UDP. GO:0106326 acetylgalactosaminyl-O-glycosyl-threonyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106326 EC:2.4.1.148|RHEA:56192 Catalysis of the reaction: 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + H(+) + UDP. GO:0106325 acetylgalactosaminyl-O-glycosyl-seryl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106325 RHEA:56188|EC:2.4.1.148 Catalysis of the reaction: 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + H(+) + UDP. GO:0106329 L-phenylalaine oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106329 RHEA:61240 Catalysis of the reaction: H2O + L-phenylalanine + O2 = 3-phenylpyruvate + H2O2 + NH4(+). GO:0072569 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072569 GO:0072568 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072568 GO:0072567 chemokine (C-X-C motif) ligand 2 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0072567 SCYB2 production|MIP-2 production|MIP2 production|CXCL2 production The appearance of chemokine (C-X-C motif) ligand 2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0072566 chemokine (C-X-C motif) ligand 1 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0072566 CXCL1 production|KC production|SCYB1 production|keratinocyte derived chemokine production The appearance of chemokine (C-X-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0072565 endothelial microparticle formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072565 endothelial microparticle generation|endothelial microparticle release The cellular component organization process in which microparticles bud off from an endothelial cell. GO:0072564 blood microparticle formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072564 microparticle generation|microparticle release The cellular component organization process in which microparticles bud off from a parent cell. A microparticle is a phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell. GO:0072563 endothelial microparticle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0072563 A blood microparticle that is derived from, and contains membrane receptors as well as other proteins characteristic of, an endothelial cell. GO:0072595 maintenance of protein localization in organelle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072595 maintenance of protein localization to organelle|maintenance of protein localisation to organelle Any process in which a protein is maintained in a specific location a specific location on or in an organelle, and is prevented from moving elsewhere. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle. GO:0106331 sialate 4-O-acetylesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106331 EC:3.1.1.53|RHEA:25564 Catalysis of the reaction: H2O + N-acetyl-4-O-acetylneuraminate = acetate + H(+) + N-acetylneuraminate. GO:0106330 sialate 9-O-acetylesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106330 EC:3.1.1.53|RHEA:22600 Catalysis of the reaction: H2O + N-acetyl-9-O-acetylneuraminate = acetate + H(+) + N-acetylneuraminate. GO:0072594 establishment of protein localization to organelle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072594 establishment of protein localisation to organelle The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle. GO:0072593 reactive oxygen species metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072593 reactive oxygen species metabolism|ROS metabolic process The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers. GO:0072592 oxygen metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072592 diatomic oxygen metabolic process|oxygen metabolism The chemical reactions and pathways involving diatomic oxygen (O2). GO:0072591 citrate-L-glutamate ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0072591 Catalysis of the reaction: ATP + citrate + L-glutamate = ADP + phosphate + beta-citryl-L-glutamate. GO:0106335 tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106335 RHEA:43208|EC:2.1.1.229 Catalysis of the reaction: carboxymethyluridine34 in tRNA + S-adenosyl-L-methionine = 5-(2-methoxy-2-oxoethyl)uridine34 in tRNA + S-adenosyl-L-homocysteine. GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0072590 Reactome:R-HSA-8942575 Catalysis of the reaction: ATP + N-acetyl-L-aspartate + L-glutamate = ADP + phosphate + N-acetylaspartyl-glutamate. GO:0106334 3'-deoxyribose phosphate lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106334 3'-dRP lyase|3'-dRP lyase activity Catalysis of the conversion of a 3'-deoxyribose phosphate in DNA to a 3'-phosphate. GO:0106333 subcortical maternal complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0106333 SCMC Comprised of at least NLRP5, OOEP, TLE6, and KHDC3/KHDC3L with evidence of additional SCMC-associated proteins that interact with one or multiple members of the core complex. UBERON:2001073 axial vasculature biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_2001073 GO:0106332 ds/ssDNA junction-specific dsDNA endonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106332 Catalysis of the endonucleolytic cleavage of double-stranded DNA near a double-strand/single-strand DNA junction. GO:0106339 tRNA (cytidine 32-2'-O)-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106339 Catalysis of the reaction: S-adenosyl-L-methionine + cytosine32 in tRNA= S-adenosyl-L-homocysteine + 2'-O-methylcytidine32 in tRNA. GO:0106336 yolk syncytial layer development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106336 YSL development The progression of the yolk syncytial layer over time, from its initial formation to the mature structure. The yolk syncytial layer is the peripheral layer of the yolk cell including nuclei and non-yolky cytoplasm. GO:0072599 establishment of protein localization to endoplasmic reticulum biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072599 establishment of protein localization to ER|establishment of protein localization in endoplasmic reticulum|establishment of protein localisation to ER|establishment of protein localisation to endoplasmic reticulum The directed movement of a protein to a specific location in the endoplasmic reticulum. GO:0072598 protein localization to chloroplast biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072598 protein localisation to chloroplast A process in which a protein is transported to, or maintained at, a location in a chloroplast. GO:0072597 maintenance of protein location in chloroplast biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072597 Any process in which a protein is maintained in a specific location in a chloroplast, and is prevented from moving elsewhere. GO:0072596 establishment of protein localization to chloroplast biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072596 establishment of protein localisation to chloroplast The directed movement of a protein to a specific location in a chloroplast. GO:0072584 caveolin-mediated endocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072584 caveolae-dependent endocytosis|caveolin-dependent endocytosis|caveolae-mediated endocytosis An endocytosis process that begins when material is taken up into plasma membrane caveolae, which then pinch off to form endocytic caveolar carriers. GO:0106342 omega-hydroxyceramide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106342 The chemical reactions and pathways resulting in the formation of omega-hydroxyceramide/acylceramide. GO:0106341 omega-hydroxyceramide transacylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106341 RHEA:55264 Catalysis of the reaction: 1,2,3-tri-(9Z,12Z)-octadecadienoylglycerol + N-(30-hydroxytriacontanoyl)-sphing-4-enine = di-(9Z,12Z)-octadecadienoylglycerol + N-[30-(9Z,12Z-octadecadienoyloxy)-triacontanoyl]-sphing-4-enine. GO:0072583 clathrin-dependent endocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072583 clathrin-dependent endocytosis|clathrin coated pit-dependent endocytosis|clathrin-mediated endocytosis|CME An endocytosis process that begins when material is taken up into clathrin-coated pits, which then pinch off to form clathrin-coated endocytic vesicles. GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0072582 RHEA:24616 Catalysis of the reaction: a 17-beta-hydroxysteroid + NADP+ = a 17-oxosteroid + NADPH + H+. GO:0106340 tRNA (guanosine 32-2'-O)-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106340 Catalysis of the reaction: S-adenosyl-L-methionine + guanosine 32 in tRNA= S-adenosyl-L-homocysteine + 2'-O-methylguanosine 32 in tRNA. GO:0072581 protein-N6-(L-lysyl)-L-lysine modification to protein-N6-(beta-lysyl)-L-lysine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072581 The modification of an N6-(lysyl)-L-lysine residue in a protein, producing protein-N6-(beta-lysyl)-L-lysine ((2S)-2-amino-6-([(2S)-2,6-diaminohexanoyl]amino)hexanoic acid). This modification is observed in, and is probably unique to, translation elongation factor P (EF-P). GO:0072580 bacterial-type EF-P lysine modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072580 EF-P modification pathway The modification of a lysine residue in a protein to produce (2S)-2-amino-6-([(3S)-3,6-diaminohexanoyl]amino)hexanoic acid, and the subsequent hydroxylation of the modified lysine residue. This modification is observed in, and is probably unique to, the prokaryotic translation elongation factor P (EF-P). GO:0106346 snRNA methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106346 Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in an snRNA molecule. GO:0106345 glyoxylate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106345 Catalysis of the reaction: glycolate + NAD(P)+ = glyoxylate + NAD(P)H. GO:0106344 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity from histidine and PLP biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106344 Catalysis of the reaction: 2 Fe(3+) + 4 H2O + L-histidyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] + N(6)-(pyridoxal phosphate)-L-lysyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] = (2S)-2-amino-5-hydroxy-4-oxopentanoyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] + 3-oxopropanoate + 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 2 Fe(2+) + 2 H(+) + L-lysyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase]. GO:0106343 glutarate dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106343 EC:1.14.11.64|RHEA:13821 Catalysis of the reaction glutarate + 2-oxoglutarate + O2 = (S)-2-hydroxyglutarate + succinate + CO2. GO:0106349 snRNA methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106349 The posttranscriptional addition of methyl groups to specific residues in an snRNA molecule. GO:0106348 U2 snRNA adenosine m6 methytransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106348 Catalysis of the reaction: a adenosine in U2 snRNA + S-adenosyl-L-methionine = an N6-methyl-adenosine in U2 snRNA + S-adenosyl-L-homocysteine + H+. GO:0106347 U2 snRNA 2'-O-methyladenosine m6 methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106347 RHEA:62672 Catalysis of the reaction: a 2'-O-methyladenosine in U2 snRNA + S-adenosyl-L-methionine = an N6-methyl-2'-O-methyladenosine in U2 snRNA + S-adenosyl-L-homocysteine + H+. GO:0072589 box H/ACA scaRNP complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0072589 nucleoplasmic box H/ACA RNP pseudouridylase complex A box H/ACA RNP complex that is located in the Cajal body of the nucleoplasm. In higher eukaryotes, box H/ACA RNP located in Cajal bodies mediate pseudouridylation of spliceosomal snRNAs. GO:0072588 box H/ACA RNP complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0072588 box H/ACA snoRNP pseudouridylase complex|sRNP complex A ribonucleoprotein complex that contains an RNA of the box H/ACA type and the four core proteins dyskerin, NOP10, NHP2, and GAR1 (human protein nomenclature). RNA pseudouridylation (isomerization of uridine to pseudouridine) is the major, and most likely the ancestral, function of H/ACA RNPs. Pseudouridylation targets include both large and small ribosomal RNAs (rRNAs), and small nuclear RNA (U2 snRNA). In addition to these catalytic H/ACA RNPs, a less abundant but more diverse class of structural H/ACA RNPs exists, which does not have pseudouridylation activity. These include the vertebrate telomerase RNP complex. GO:0072587 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0072587 Binds to and increases the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2. GO:0072586 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0072586 Modulates the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2. GO:0072585 xanthosine nucleotidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0072585 RHEA:27994|MetaCyc:RXN0-363 xanthosine ribohydrolase activity Catalysis of the reaction: xanthosine + H2O = D-ribose + xanthine. GO:0106302 arachidonic acid 8,9-epoxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106302 RHEA:64984 Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to cis-8,9-epoxyeicosatrienoic acid. GO:0106301 arachidonic acid 5,6-epoxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106301 RHEA:49936 Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to cis-5,6-epoxyeicosatrienoic acid. GO:0106300 protein-DNA covalent cross-linking repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106300 resolution of protein-DNA covalent cross-linking The removal of covalent cross-link between DNA and a protein. GO:0106306 protein serine phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106306 RHEA:20629|EC:3.1.3.16 Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate. GO:0106305 mannogen catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106305 beta-1,2-mannan catabolic process|mannogen degradation|beta-1,2-mannan catabolism|mannogen catabolism|mannogen breakdown The chemical reactions and pathways resulting in the breakdown of mannogen, a mannose-containing polysaccharide that is a major energy reserve in Leishmania. GO:0106304 mannogen biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106304 mannogen anabolism|mannogen synthesis|mannogen formation|beta-1,2-mannan biosynthetic process|mannogen biosynthesis The chemical reactions and pathways resulting in the formation of mannogen, a mannose-containing polysaccharide that is a major energy reserve in Leishmania. GO:0106303 mannogen metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106303 mannogen metabolism|beta-1,2-mannan metabolic process The chemical reactions and pathways involving mannogen, a mannose-containing polysaccharide that is a major energy reserve in Leishmania. GO:0106309 progesterone 21-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106309 RHEA:50304 Catalysis of the reaction: O2 + progesterone + reduced [NADPH--hemoprotein reductase] = 21-hydroxyprogesterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]. GO:0106307 protein threonine phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106307 RHEA:47004|EC:3.1.3.16 Catalysis of the reaction: protein threonine phosphate + H2O = protein threonine + phosphate. OBA:1000227 lens of camera-type eye quality biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_1000227 quality of lens of camera-type eye The quality of a lens of camera-type eye. CHEBI:24646 hydroquinones biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_24646 CHEBI:24644 HPETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24644 GO:0047537 2-aminohexanoate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047537 MetaCyc:2-AMINOHEXANOATE-AMINOTRANSFERASE-RXN|EC:2.6.1.67|RHEA:23600 leucine L-norleucine: 2-oxoglutarate aminotransferase activity|norleucine aminotransferase activity|L-2-aminohexanoate:2-oxoglutarate aminotransferase activity|norleucine (leucine) aminotransferase activity|norleucine transaminase activity|2-aminohexanoate aminotransferase activity Catalysis of the reaction: L-2-aminohexanoate + 2-oxoglutarate = 2-oxohexanoate + L-glutamate. GO:0047536 2-aminoadipate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047536 Reactome:R-HSA-70952|MetaCyc:2-AMINOADIPATE-AMINOTRANSFERASE-RXN|KEGG_REACTION:R01939|Reactome:R-HSA-508561|EC:2.6.1.39|RHEA:12601 glutamic-ketoadipic transaminase activity|2-aminoadipate aminotransferase activity|glutamate-alpha-ketoadipate transaminase activity|2-aminoadipic aminotransferase activity|L-2-aminoadipate:2-oxoglutarate aminotransferase activity|alpha-aminoadipate aminotransferase activity Catalysis of the reaction: 2-oxoglutarate + L-2-aminoadipate = 2-oxoadipate + L-glutamate. GO:0047535 2-alkyn-1-ol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047535 RHEA:19101|MetaCyc:2-ALKYN-1-OL-DEHYDROGENASE-RXN|EC:1.1.1.165|KEGG_REACTION:R03963 2-butyne-1,4-diol:NAD+ 1-oxidoreductase activity Catalysis of the reaction: 2-butyne-1,4-diol + NAD(+) = 4-hydroxy-2-butynal + H(+) + NADH. GO:0047534 2-acetolactate mutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047534 RHEA:16361|EC:5.4.99.3|MetaCyc:2-ACETOLACTATE-MUTASE-RXN acetohydroxy acid isomerase activity|acetolactate mutase activity|2-acetolactate methylmutase activity Catalysis of the reaction: 2-acetolactate = 3-hydroxy-3-methyl-2-oxobutanoate. GO:0047533 2,5-dioxovalerate dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047533 RHEA:11296|EC:1.2.1.26|MetaCyc:25-DIOXOVALERATE-DEHYDROGENASE-RXN 2,5-dioxopentanoate:NADP+ 5-oxidoreductase activity|alpha-ketoglutaric semialdehyde dehydrogenase activity|2-oxoglutarate semialdehyde dehydrogenase activity Catalysis of the reaction: 2,5-dioxopentanoate + NADP+ + H2O = 2-oxoglutarate + NADPH + H+. GO:0047532 2,5-dioxopiperazine hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047532 RHEA:21808|MetaCyc:25-DIOXOPIPERAZINE-HYDROLASE-RXN|EC:3.5.2.13|KEGG_REACTION:R03810 cyclo(glycylglycine) hydrolase activity|cyclo(Gly-Gly) hydrolase activity|2,5-dioxopiperazine amidohydrolase activity Catalysis of the reaction: 2,5-dioxopiperazine + H(2)O = glycylglycine. GO:0047531 2,5-diaminovalerate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047531 MetaCyc:25-DIAMINOVALERATE-AMINOTRANSFERASE-RXN|KEGG_REACTION:R03248|EC:2.6.1.8|RHEA:16017 diamino-acid transaminase activity|2,5-diaminopentanoate:2-oxoglutarate aminotransferase activity|diamino-acid aminotransferase activity|2,5-diaminovalerate aminotransferase activity|diamino acid aminotransferase activity Catalysis of the reaction: 2-oxoglutarate + ornithine = 5-amino-2-oxopentanoate + L-glutamate. GO:0047530 2,4-diaminopentanoate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047530 EC:1.4.1.12|MetaCyc:24-DIAMINOPENTANOATE-DEHYDROGENASE-RXN 2,4-diaminopentanoate:NAD(P)+ oxidoreductase (deaminating)|2,4-diaminopentanoic acid C4 dehydrogenase activity Catalysis of the reaction: 2,4-diaminopentanoate + H2O + NAD(P)+ = 2-amino-4-oxopentanoate + NH3 + NAD(P)H + H+. GO:0047539 2-deoxyglucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047539 EC:3.2.1.112|MetaCyc:2-DEOXYGLUCOSIDASE-RXN|RHEA:15317 2-deoxy-alpha-D-glucosidase activity|2-deoxy-alpha-glucosidase activity|2-deoxy-alpha-D-glucoside deoxyglucohydrolase activity Catalysis of the reaction: H2O + a 2-deoxy-alpha-D-glucoside = 2-deoxy-D-glucose + an alcohol. GO:0047538 2-carboxy-D-arabinitol-1-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047538 KEGG_REACTION:R04167|MetaCyc:2-CARBOXY-D-ARABINITOL-1-PHOSPHATASE-RXN|RHEA:17837|EC:3.1.3.63 2-carboxy-D-arabinitol 1-phosphate phosphohydrolase activity|2-carboxy-D-arabinitol-1-phosphate 1-phosphohydrolase activity|2-carboxyarabinitol 1-phosphatase activity Catalysis of the reaction: 2-carboxy-D-arabinitol 1-phosphate + H(2)O = 2-carboxy-D-arabinitol + phosphate. CHEBI:24648 hydroxamic acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24648 GO:0047540 2-enoate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047540 EC:1.3.1.31|RHEA:10200|MetaCyc:2-ENOATE-REDUCTASE-RXN butanoate:NAD+ delta2-oxidoreductase activity|enoate reductase activity Catalysis of the reaction: butanoate + NAD+ = 2-butenoate + NADH + H+. CHEBI:24654 hydroxy fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24654 CHEBI:48600 arsenate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48600 CHEBI:24651 hydroxides biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24651 CHEBI:24658 hydroxy-L-arginine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24658 CHEBI:48604 carnitinamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48604 GO:0047548 2-methyleneglutarate mutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047548 KEGG_REACTION:R03908|EC:5.4.99.4|RHEA:13793|MetaCyc:2-METHYLENEGLUTARATE-MUTASE-RXN 2-methyleneglutarate carboxy-methylenemethylmutase activity|alpha-methyleneglutarate mutase activity Catalysis of the reaction: 2-methyleneglutarate = 2-methylene-3-methylsuccinate. GO:0047547 2-methylcitrate dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047547 EC:4.2.1.79|MetaCyc:2-METHYLCITRATE-DEHYDRATASE-RXN|KEGG_REACTION:R04424|RHEA:17725 (2S,3S)-2-hydroxybutane-1,2,3-tricarboxylate hydro-lyase [(Z)-but-2-ene-1,2,3-tricarboxylate-forming]|2-hydroxybutane-1,2,3-tricarboxylate hydro-lyase activity|prpD|2-methylcitrate hydro-lyase activity Catalysis of the reaction: (2S,3S)-2-methylcitrate = cis-2-methylaconitate + H(2)O. GO:0047546 2-hydroxypyridine 5-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047546 KEGG_REACTION:R03206|RHEA:16973|MetaCyc:2-HYDROXYPYRIDINE-5-MONOOXYGENASE-RXN|EC:1.14.99.26 2-hydroxypyridine oxygenase activity|2-hydroxypyridine,hydrogen-donor:oxygen oxidoreductase (5-hydroxylating) Catalysis of the reaction: 2-hydroxypyridine + AH(2) + O(2) = 2,5-dihydroxypyridine + A + H(2)O. GO:0047545 2-hydroxyglutarate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047545 Reactome:R-HSA-880050|RHEA:21252|EC:1.1.99.2|MetaCyc:2-HYDROXYGLUTARATE-DEHYDROGENASE-RXN alpha-hydroxyglutarate dehydrogenase activity|L-alpha-hydroxyglutarate dehydrogenase activity|L-alpha-hydroxyglutarate:NAD+ 2-oxidoreductase|(S)-2-hydroxyglutarate:acceptor 2-oxidoreductase|hydroxyglutaric dehydrogenase activity|alpha-hydroxyglutarate oxidoreductase activity|(S)-2-hydroxyglutarate:(acceptor) 2-oxidoreductase|alpha-hydroxyglutarate dehydrogenase (NAD+ specific) Catalysis of the reaction: (S)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor. GO:0047544 2-hydroxybiphenyl 3-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047544 UM-BBD_reactionID:r1423|RHEA:11996|KEGG_REACTION:R03964|MetaCyc:2-HYDROXYBIPHENYL-3-MONOOXYGENASE-RXN|EC:1.14.13.44 2-hydroxybiphenyl,NADH:oxygen oxidoreductase (3-hydroxylating) Catalysis of the reaction: biphenyl-2-ol + H(+) + NADH + O(2) = biphenyl-2,3-diol + H(2)O + NAD(+). CHEBI:24650 hydroxamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24650 GO:0047543 2-hexadecenal reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047543 EC:1.3.1.27|MetaCyc:2-HEXADECENAL-REDUCTASE-RXN|RHEA:12444|KEGG_REACTION:R02463 hexadecanal: NADP+ oxidoreductase activity|hexadecanal:NADP+ delta2-oxidoreductase activity Catalysis of the reaction: NADP(+) + palmitaldehyde = trans-hexadec-2-enal + H(+) + NADPH. GO:0047542 2-furoyl-CoA dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047542 MetaCyc:2-FUROYL-COA-DEHYDROGENASE-RXN|KEGG_REACTION:R02987|RHEA:21480|EC:1.3.99.8 2-furoyl-CoA:acceptor 5-oxidoreductase (hydroxylating)|2-furoyl coenzyme A hydroxylase activity|2-furoyl-CoA:(acceptor) 5-oxidoreductase (hydroxylating)|furoyl-CoA hydroxylase activity|2-furoyl coenzyme A dehydrogenase activity Catalysis of the reaction: 2-furoyl-CoA + A + H(2)O = 5-hydroxy-2-furoyl-CoA + AH(2) + H(+). GO:0047541 2-furoate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047541 MetaCyc:2-FUROATE--COA-LIGASE-RXN|KEGG_REACTION:R02986|EC:6.2.1.31|RHEA:19269 2-furoate:CoA ligase (AMP-forming)|2-furoyl coenzyme A synthetase activity Catalysis of the reaction: 2-furoate + ATP + CoA = 2-furoyl-CoA + AMP + diphosphate + H(+). GO:0047549 2-nitrophenol 2-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047549 EC:1.14.13.31|KEGG_REACTION:R00828|UM-BBD_reactionID:r1494|MetaCyc:2-NITROPHENOL-2-MONOOXYGENASE-RXN|RHEA:19457 2-nitrophenol oxygenase activity|nitrophenol oxygenase activity|2-nitrophenol,NADPH:oxygen 2-oxidoreductase (2-hydroxylating, nitrite-forming) Catalysis of the reaction: 2-nitrophenol + 2 H(+) + 2 NADPH + O(2) = catechol + H(2)O + 2 NADP(+) + nitrite. CHEBI:24659 hydroxy-L-glutamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24659 GO:0047551 2-oxoaldehyde dehydrogenase (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047551 EC:1.2.1.23|Wikipedia:2-oxoaldehyde_dehydrogenase_(NAD+)|RHEA:22276|MetaCyc:2-OXOALDEHYDE-DEHYDROGENASE-NAD+-RXN NAD-dependent alpha-ketoaldehyde dehydrogenase activity|2-ketoaldehyde dehydrogenase|alpha-ketoaldehyde dehydrogenase activity|NAD-linked alpha-ketoaldehyde dehydrogenase activity|methylglyoxal dehydrogenase activity|2-oxoaldehyde dehydrogenase (NAD+)|2-oxoaldehyde:NAD+ 2-oxidoreductase activity Catalysis of the reaction: a 2-oxoaldehyde + NAD+ + H2O = a 2-oxo acid + NADH + H+. CHEBI:24621 hormone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24621 GO:0047550 2-oxoadipate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047550 MetaCyc:2-OXOADIPATE-REDUCTASE-RXN|EC:1.1.1.172|KEGG_REACTION:R01932|RHEA:14793 alpha-ketoadipate reductase activity|2-hydroxyadipate:NAD+ 2-oxidoreductase activity|2-ketoadipate reductase activity Catalysis of the reaction: 2-hydroxyadipate + NAD(+) = 2-oxoadipate + H(+) + NADH. GO:0047559 3-dehydro-L-gulonate 2-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047559 MetaCyc:3-DEHYDRO-L-GULONATE-2-DEHYDROGENASE-RXN|EC:1.1.1.130 3-dehydro-L-gulonate:NAD(P)+ 2-oxidoreductase activity|3-keto-L-gulonate dehydrogenase activity|2,3-diketo-L-gulonate reductase activity|3-ketogulonate dehydrogenase activity Catalysis of the reaction: 3-dehydro-L-gulonate + NAD(P)+ = (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NAD(P)H + H+. GO:0047558 3-cyanoalanine hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047558 RHEA:15385|MetaCyc:3-CYANOALANINE-HYDRATASE-RXN|EC:4.2.1.65|KEGG_REACTION:R01267 L-asparagine hydro-lyase (3-cyanoalanine-forming)|beta-CNA nitrilase activity|beta-cyanoalanine hydrolase activity|L-asparagine hydro-lyase activity|beta-cyanoalanine hydratase activity|beta-CNAla hydrolase activity Catalysis of the reaction: L-asparagine = 3-cyano-L-alanine + H(2)O + H(+). GO:0047557 3-aci-nitropropanoate oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047557 RHEA:22372|KEGG_REACTION:R01609|MetaCyc:3-ACI-NITROPROPANOATE-OXIDASE-RXN|EC:1.7.3.5 propionate-3-nitronate oxidase activity|3-aci-nitropropanoate:oxygen oxidoreductase activity Catalysis of the reaction: 3-aci-nitropropanoate + H(2)O + O(2) = 3-oxopropanoate + H(2)O(2) + nitrite. GO:0047556 3,4-dihydroxyphthalate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047556 MetaCyc:34-DIHYDROXYPHTHALATE-DECARBOXYLASE-RXN|EC:4.1.1.69|UM-BBD_reactionID:r1447|KEGG_REACTION:R01634|RHEA:18601 3,4-dihydroxyphthalate 2-decarboxylase activity|3,4-dihydroxyphthalate carboxy-lyase activity|3,4-dihydroxyphthalate carboxy-lyase (3,4-dihydroxybenzoate-forming) Catalysis of the reaction: 3,4-dihydroxyphthalate + H(+) = 3,4-dihydroxybenzoate + CO(2). GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047555 Reactome:R-HSA-74059|Reactome:R-HSA-4086392|MetaCyc:35-CYCLIC-GMP-PHOSPHODIESTERASE-RXN|Reactome:R-HSA-418456|EC:3.1.4.35|RHEA:16957 3',5' cyclic-GMP phosphodiesterase activity|3',5'-cyclic-GMP 5'-nucleotidohydrolase activity|guanosine cyclic 3',5'-phosphate phosphodiesterase activity|cyclic guanosine 3',5'-monophosphate phosphodiesterase activity|cGMP-specific phosphodiesterase activity|cyclic guanosine 3',5'-phosphate phosphodiesterase activity|cyclic GMP phosphodiesterase activity|cyclic 3',5'-GMP phosphodiesterase activity|cGMP-PDE|cGMP phosphodiesterase activity Catalysis of the reaction: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate. GO:0047554 2-pyrone-4,6-dicarboxylate lactonase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047554 MetaCyc:RXN-2462|EC:3.1.1.57|RHEA:10644|KEGG_REACTION:R04277 2-pyrone-4,6-dicarboxylate lactonohydrolase activity Catalysis of the reaction: 2-oxo-2H-pyran-4,6-dicarboxylate + H(2)O = 4-carboxy-2-hydroxyhexa-2,4-dienedioate + H(+). GO:0047553 2-oxoglutarate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047553 RHEA:17297|MetaCyc:2-OXOGLUTARATE-SYNTHASE-RXN|EC:1.2.7.3 alpha-ketoglutarate-ferredoxin oxidoreductase activity|2-ketoglutarate ferredoxin oxidoreductase activity|2-oxoglutarate ferredoxin oxidoreductase activity|alpha-ketoglutarate synthase activity|KGOR activity|2-oxoglutarate:ferredoxin oxidoreductase activity|2-oxoglutarate:ferredoxin 2-oxidoreductase (CoA-succinylating)|2-oxoglutarate:ferredoxin 2-oxidoreductase (decarboxylating) Catalysis of the reaction: 2-oxoglutarate + CoA + oxidized ferredoxin = succinyl-CoA + CO2 + reduced ferredoxin. GO:0047552 2-oxoaldehyde dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047552 EC:1.2.1.49|MetaCyc:2-OXOALDEHYDE-DEHYDROGENASE-NADP+-RXN|RHEA:18129 methylglyoxal dehydrogenase activity|NADP-dependent alpha-ketoaldehyde dehydrogenase activity|NADP-linked alpha-ketoaldehyde dehydrogenase activity|2-oxoaldehyde:NADP+ 2-oxidoreductase activity|2-ketoaldehyde dehydrogenase|alpha-ketoaldehyde dehydrogenase activity Catalysis of the reaction: a 2-oxoaldehyde + NADP+ + H2O = a 2-oxo acid + NADPH + H+. UBERON:0001491 wrist joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001491 radiocarpal joint|joint of wrist|joint of carpal region|carpal region joint A joint connecting the forelimb zeugopod skeleton with the carpal skeleton. UBERON:0001490 elbow joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001490 joint of elbow|joint of cubital region|articulatio cubiti|cubital region joint A joint that connects the forelimb zeugopod and stylopod skeletons[Obol]. UBERON:0001493 axillary nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001493 circumflex nerve|auxillery nerve|circumflex humeral nerve|nervus axillaris The axillary nerve is a nerve of the human body, that comes off the posterior cord of the brachial plexus at the level of the axilla (armpit) and carries nerve fibers from C5 and C6. The axillary nerve travels through the quadrangular space with the posterior circumflex humeral artery and vein. [WP,unvetted]. GO:0072519 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072519 GO:0072518 Rho-dependent protein serine/threonine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0072518 Rho-associated protein kinase activity|ROCK kinase activity Rho GTPase-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. GO:0072517 host cell viral assembly compartment biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0072517 host cell viral assembly site|virion assembly compartment|viral assembly compartment|viral assembly site|host cell virion assembly compartment A membrane-bounded compartment that forms in the cytoplasm of the host cell, in which virus assembly takes place. GO:0072516 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072516 UBERON:0001499 muscle of arm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001499 arm muscle system|arm muscle|arm skeletal muscle|arm skeletal muscle tissue|upper arm / lower arm muscle|muscle of upper arm or lower arm A muscle organ that is part of an arm [Automatically generated definition]. GO:0072515 trehalose transport in response to desiccation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072515 The directed movement of trehalose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore, that occurs as a result of a desiccation stimulus. A desiccation stimulus signals extreme dryness resulting from the prolonged deprivation of water. CHEBI:24628 imidazolidine-2,4-dione biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24628 GO:0072514 trehalose transport in response to water deprivation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072514 The directed movement of trehalose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore, that occurs as a result of deprivation of water. UBERON:0001498 muscle of pes biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001498 foot muscle organ|muscle of foot|foot muscle|muscle organ of foot Any muscle organ that is part of a pes [Automatically generated definition]. GO:0072513 positive regulation of secondary heart field cardioblast proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072513 negative regulation of second heart field cardioblast proliferation Any process that activates or increases the frequency, rate or extent of cardioblast proliferation in the second heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. The secondary heart field is the region of the heart that will form the majority of the mesodermal component of the right ventricle, the arterial pole (outflow tract) and the venous pole (inflow tract). GO:0072512 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072512 GO:0072511 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072511 GO:0072510 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072510 UBERON:0001497 muscle of pelvic girdle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001497 muscle organ of girdle-pelvic|pelvic girdle muscle organ|pelvic girdle skeletal muscle|muscle organ of pelvic girdle|girdle-pelvic muscle organ|pelvic girdle muscle|muscle organ of pelvic girdle bone Any muscle organ that is part of a pelvic girdle [Automatically generated definition]. UBERON:0001496 ascending aorta biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001496 aorta ascendens|ascending thoracic aorta|pars ascendens aortae|pars ascendens aortae The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta[GO]. A portion of the aorta commencing at the upper part of the base of the left ventricle, on a level with the lower border of the third costal cartilage behind the left half of the sternum; it passes obliquely upward, forward, and to the right, in the direction of the heart's axis, as high as the upper border of the second right costal cartilage, describing a slight curve in its course, and being situated, about 6 cm behind the posterior surface of the sternum. The total length is about 5 cm in length [Wikipedia] CHEBI:24632 hydrocarbon biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24632 GO:0047562 3-hydroxyaspartate aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047562 EC:4.1.3.14|KEGG_REACTION:R00478|RHEA:14377|MetaCyc:3-HYDROXYASPARTATE-ALDOLASE-RXN erythro-3-hydroxy-L(s)-aspartate glyoxylate-lyase activity|erythro-3-hydroxy-Ls-aspartate glyoxylate-lyase activity|erythro-3-hydroxy-Ls-aspartate glyoxylate-lyase (glycine-forming)|erythro-beta-hydroxyaspartate glycine-lyase activity|erythro-beta-hydroxyaspartate aldolase activity Catalysis of the reaction: (3R)-3-hydroxy-L-aspartate = glycine + glyoxylate. GO:0047561 3-hydroxyanthranilate oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047561 KEGG_REACTION:R02666|RHEA:17245|EC:1.10.3.5|MetaCyc:3-HYDROXYANTHRANILATE-OXIDASE-RXN 3-hydroxyanthranilic acid oxidase activity|3-hydroxyanthranilate:oxygen oxidoreductase activity Catalysis of the reaction: 3-hydroxyanthranilate + O(2) = 6-imino-5-oxocyclohexa-1,3-dienecarboxylate + H(2)O(2). CHEBI:24631 hydrazines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24631 GO:0047560 3-dehydrosphinganine reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047560 Reactome:R-HSA-428123|RHEA:22640|MetaCyc:3-DEHYDROSPHINGANINE-REDUCTASE-RXN|EC:1.1.1.102|KEGG_REACTION:R02978 3-ketosphinganine reductase activity|D-3-dehydrosphinganine reductase activity|3-oxosphinganine reductase activity|3-oxosphinganine:NADPH oxidoreductase activity|D-3-oxosphinganine:B-NADPH oxidoreductase activity|D-3-oxosphinganine reductase activity|DSR activity|KTS reductase activity|D-erythro-dihydrosphingosine:NADP+ 3-oxidoreductase activity Catalysis of the reaction: NADP(+) + sphinganine = 3-dehydrosphinganine + H(+) + NADPH. CHEBI:24636 proton biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24636 GO:0047569 3-oxoadipate CoA-transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047569 EC:2.8.3.6|MetaCyc:3-OXOADIPATE-COA-TRANSFERASE-RXN|RHEA:12048|UM-BBD_reactionID:r1050 succinyl-CoA:3-oxoadipate CoA-transferase activity|3-oxoadipate coenzyme A-transferase activity|3-oxoadipate succinyl-CoA transferase activity|beta-ketoadipate:succinyl-CoA transferase activity Catalysis of the reaction: succinyl-CoA + 3-oxoadipate = succinate + 3-oxoadipyl-CoA. GO:0047568 3-oxo-5-beta-steroid 4-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047568 MetaCyc:3-OXO-5-BETA-STEROID-4-DEHYDROGENASE-RXN|RHEA:24172|EC:1.3.99.6 3-oxo-5beta-steroid 4-dehydrogenase activity|3-oxo-5beta-steroid:acceptor delta4-oxidoreductase activity|delta4-3-ketosteroid 5-beta-reductase activity|3-oxo-5beta-steroid:(acceptor) delta4-oxidoreductase activity Catalysis of the reaction: a 3-oxo-5-beta-steroid + acceptor = a 3-oxo-D4-steroid + reduced acceptor. GO:0047567 3-methyleneoxindole reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047567 MetaCyc:3-METHYLENEOXINDOLE-REDUCTASE-RXN|RHEA:20257|KEGG_REACTION:R03930|EC:1.3.1.17 3-methyloxindole:NADP+ oxidoreductase activity|3-methyl-1,3-dihydroindol-2-one:NADP+ oxidoreductase activity Catalysis of the reaction: 3-methyloxindole + NADP(+) = 3-methyleneoxindole + H(+) + NADPH. GO:0047566 3-ketovalidoxylamine C-N-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047566 RHEA:22768|KEGG_REACTION:R04367|MetaCyc:3-KETOVALIDOXYLAMINE-C-N-LYASE-RXN|EC:4.3.3.1 4-nitrophenyl-3-ketovalidamine 4-nitroaniline-lyase activity|3-ketovalidoxylamine A C-N-lyase activity|p-nitrophenyl-3-ketovalidamine p-nitroaniline lyase activity|4-nitrophenyl-3-ketovalidamine 4-nitroaniline-lyase [5-D-(5/6)-5-C-(hydroxymethyl)-2,6-dihydroxycyclohex-2-en-1-one-forming] Catalysis of the reaction: 4-nitrophenyl-3-ketovalidamine = 4-nitroaniline + 5-D-(5/6)-5-C-(hydroxymethyl)-2,6-dihydroxycyclohex-2-en-1-one + H(+). GO:0047565 3-hydroxypropionate dehydrogenase (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047565 MetaCyc:3-HYDROXYPROPIONATE-DEHYDROGENASE-RXN|RHEA:13357|KEGG_REACTION:R01608|EC:1.1.1.59 3-hydroxypropanoate:NAD+ oxidoreductase activity Catalysis of the reaction: 3-hydroxypropanoate + NAD(+) = 3-oxopropanoate + H(+) + NADH. GO:0047564 3-hydroxycyclohexanone dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047564 RHEA:15905|KEGG_REACTION:R03212|MetaCyc:3-HYDROXYCYCLOHEXANONE-DEHYDROGENASE-RXN|EC:1.1.99.26 3-hydroxycyclohexanone:acceptor 1-oxidoreductase activity Catalysis of the reaction: 3-hydroxycyclohexanone + A = AH(2) + cyclohexane-1,3-dione. GO:0047563 3-hydroxybenzoate 2-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047563 RHEA:14193|EC:1.14.99.23|MetaCyc:3-HYDROXYBENZOATE-2-MONOOXYGENASE-RXN|KEGG_REACTION:R01508 3-hydroxybenzoate 2-hydroxylase activity|3-HBA-2-hydroxylase activity|3-hydroxybenzoate,hydrogen-donor:oxygen oxidoreductase (2-hydroxylating) Catalysis of the reaction: 3-hydroxybenzoate + AH(2) + O(2) = 2,3-dihydroxybenzoate + A + H(2)O. UBERON:0001480 proximal carpal bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001480 A carpal bone that proximally_connected_to a forelimb zeugopod skeleton. UBERON:0001482 muscle of shoulder biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001482 shoulder muscle organ|shoulder muscle|muscle organ of shoulder Any muscle organ that is part of a shoulder [Automatically generated definition]. GO:0072509 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072509 GO:0072508 trivalent inorganic cation homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072508 Any process involved in the maintenance of an internal steady state of trivalent cations within an organism or cell. GO:0072507 divalent inorganic cation homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072507 Any process involved in the maintenance of an internal steady state of divalent cations within an organism or cell. GO:0072506 trivalent inorganic anion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072506 Any process involved in the maintenance of an internal steady state of trivalent inorganic anions within an organism or cell. GO:0072505 divalent inorganic anion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072505 Any process involved in the maintenance of an internal steady state of divalent inorganic anions within an organism or cell. CHEBI:10003 ribostamycin sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_10003 UBERON:0001488 ankle joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001488 talotibial joint|hock joint|mortise joint|talocrural articulation|hock|gambrel|talocrural joint A joint that connects the hindlimb autopod and zeugopod skeletons. GO:0072504 cellular trivalent inorganic cation homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072504 Any process involved in the maintenance of an internal steady state of trivalent cations at the level of a cell. UBERON:0001487 pes joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001487 articulationes pedis|pedal joint|joints of foot|hind limb autopod joint|joint of terminal segment of free lower limb|foot joint|joint of pes A skeletal joint that is part of a pes [Automatically generated definition]. GO:0072503 cellular divalent inorganic cation homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072503 Any process involved in the maintenance of an internal steady state of divalent cations at the level of a cell. GO:0072502 cellular trivalent inorganic anion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072502 Any process involved in the maintenance of an internal steady state of trivalent inorganic anions at the level of a cell. GO:0072501 cellular divalent inorganic anion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072501 Any process involved in the maintenance of an internal steady state of divalent inorganic anions at the level of a cell. UBERON:0001489 manus joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001489 articulationes manus|joint of manus|joint of hand|joint of terminal segment of free upper limb|hand joint|manual joint A skeletal joint that is part of a manus (hand) [Automatically generated definition]. GO:0072500 obsolete negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072500 negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor OBSOLETE. Any process in which a ligand-bound hormone receptor acts in the nucleus to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter. UBERON:0001484 articular capsule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001484 fibrous capsule of joint|capsula articularis|joint capsule|joint fibrous capsule|capsulae articulares An articular capsule (or joint capsule) is an envelope surrounding a synovial joint. [WP,unvetted]. UBERON:0001483 skin of shoulder biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001483 shoulder skin|zone of skin of shoulder|shoulder zone of skin A zone of skin that is part of a shoulder region. UBERON:0001485 knee joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001485 joint of knee|articulatio genus The knee joint joins the thigh with the leg and consists of two articulations: one between the femur and tibia, and one between the femur and patella. It is the largest and most complicated joint in the human body. The knee is a mobile trocho-ginglymus (i.e. a pivotal hinge joint), which permits flexion and extension as well as a slight medial and lateral rotation[WP,unvetted]. GO:0047573 4-acetamidobutyrate deacetylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047573 MetaCyc:4-ACETAMIDOBUTYRATE-DEACETYLASE-RXN|RHEA:15897|EC:3.5.1.63 4-acetamidobutanoate amidohydrolase activity Catalysis of the reaction: 4-acetamidobutanoate + H2O = acetate + 4-aminobutanoate. GO:0106352 aspartate dehydrogenase NADP activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106352 RHEA:11784 Catalysis of the reaction: L-aspartate + H2O + NADP+ = oxaloacetate + NH3 + NADPH+ H+. GO:0047572 3-phosphoglycerate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047572 EC:3.1.3.38|KEGG_REACTION:R01511|RHEA:12412|MetaCyc:3-PHOSPHOGLYCERATE-PHOSPHATASE-RXN D-3-phosphoglycerate phosphatase activity|D-glycerate-3-phosphate phosphohydrolase activity|3-PGA phosphatase activity Catalysis of the reaction: 3-phospho-D-glycerate + H(2)O = D-glycerate + phosphate. GO:0106351 aspartate dehydrogenase NAD activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106351 RHEA:11788 Catalysis of the reaction: L-aspartate + H2O + NAD+ = oxaloacetate + NH3 + NADH+ H+. GO:0047571 3-oxosteroid 1-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047571 UM-BBD_enzymeID:e0712|EC:1.3.99.4|RHEA:13329|MetaCyc:3-OXOSTEROID-1-DEHYDROGENASE-RXN 1-ene-dehydrogenase activity|delta1-steroid reductase activity|3-oxosteroid:(acceptor) delta1-oxidoreductase activity|3-ketosteroid-1-en-dehydrogenase activity|4-en-3-oxosteroid:(acceptor)-1-en-oxido-reductase activity|3-oxosteroid:(2,6-dichlorphenolindophenol) delta1-oxidoreductase activity|3-oxosteroid delta1-dehydrogenase activity|3-oxosteroid:acceptor delta1-oxidoreductase activity|delta1-dehydrogenase activity|3-ketosteroid-delta1-dehydrogenase activity Catalysis of the reaction: a 3-oxosteroid + acceptor = a 3-oxo-D1-steroid + reduced acceptor. GO:0106350 octaprenyl pyrophosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106350 RHEA:27798|EC:2.5.1.90 Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + 5 isopentenyl diphosphate = 5 diphosphate + all-trans-octaprenyl diphosphate. GO:0047570 3-oxoadipate enol-lactonase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047570 EC:3.1.1.24|RHEA:10184|MetaCyc:3-OXOADIPATE-ENOL-LACTONASE-RXN 3-ketoadipate enol-lactonase activity|carboxymethylbutenolide lactonase activity|4-carboxymethylbut-3-en-4-olide enol-lactonohydrolase activity|beta-ketoadipate enol-lactone hydrolase activity|beta-ketoadipic enol-lactone hydrolase activity|3-oxoadipic enol-lactone hydrolase activity Catalysis of the reaction: 3-oxoadipate enol-lactone + H2O = 3-oxoadipate. SO:0000001 region biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000001 sequence A sequence_feature with an extent greater than zero. A nucleotide region is composed of bases and a polypeptide region is composed of amino acids. GO:0106354 tRNA surveillance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106354 The set of processes involved in identifying and degrading defective or aberrant tRNAs. GO:0047579 4-hydroxymandelate oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047579 EC:1.1.3.19|MetaCyc:4-HYDROXYMANDELATE-OXIDASE-RXN|RHEA:15833|KEGG_REACTION:R02673 L-4-hydroxymandelate oxidase (decarboxylating)|(S)-2-hydroxy-2-(4-hydroxyphenyl)acetate:oxygen 1-oxidoreductase activity Catalysis of the reaction: (S)-4-hydroxymandelate + H(+) + O(2) = 4-hydroxybenzaldehyde + CO(2) + H(2)O(2). GO:0047578 4-hydroxyglutamate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047578 MetaCyc:4-HYDROXYGLUTAMATE-AMINOTRANSFERASE-RXN|EC:2.6.1.23|Reactome:R-HSA-6784393|RHEA:10480 4-hydroxy-L-glutamate:2-oxoglutarate aminotransferase activity|4-hydroxyglutamate aminotransferase activity Catalysis of the reaction: 4-hydroxy-L-glutamate + 2-oxoglutarate = 4-hydroxy-2-oxoglutarate + L-glutamate. GO:0047577 4-hydroxybutyrate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047577 MetaCyc:4-HYDROXYBUTYRATE-DEHYDROGENASE-RXN|RHEA:23948|KEGG_REACTION:R01644|EC:1.1.1.61 gamma-hydroxybutyrate dehydrogenase activity|4-hydroxybutanoate:NAD+ oxidoreductase activity Catalysis of the reaction: 4-hydroxybutanoate + NAD(+) = H(+) + NADH + succinate semialdehyde. GO:0047576 4-chlorobenzoate dehalogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047576 KEGG_REACTION:R01307|EC:3.8.1.6|RHEA:23440|MetaCyc:4-CHLOROBENZOATE-DEHALOGENASE-RXN halobenzoate dehalogenase activity|4-chlorobenzoate chlorohydrolase activity Catalysis of the reaction: 4-chlorobenzoate + H(2)O = 4-hydroxybenzoate + chloride + H(+). GO:0047575 4-carboxymuconolactone decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047575 EC:4.1.1.44|RHEA:23348|MetaCyc:4-CARBOXYMUCONOLACTONE-DECARBOXYLASE-RXN|KEGG_REACTION:R03470 4-carboxymuconolactone carboxy-lyase (4,5-dihydro-5-oxofuran-2-acetate-forming)|4-carboxymonolactone carboxy-lyase activity|gamma-4-carboxymuconolactone decarboxylase activity|4-carboxymuconolactone carboxy-lyase activity Catalysis of the reaction: (R)-2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoate + H(+) = 5-oxo-4,5-dihydro-2-furylacetate + CO(2). GO:0047574 4-acetamidobutyryl-CoA deacetylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047574 RHEA:22928|EC:3.5.1.51|KEGG_REACTION:R04056|MetaCyc:4-ACETAMIDOBUTYRYL-COA-DEACETYLASE-RXN deacetylase-thiolesterase activity|4-acetamidobutanoyl-CoA amidohydrolase activity|aminobutyryl-CoA thiolesterase activity Catalysis of the reaction: 4-acetamidobutanoyl-CoA + H(2)O = 4-aminobutanoyl-CoA + acetate. GO:0072539 T-helper 17 cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072539 T-helper 17 cell development The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 17 (Th17) cell. A Th17 cell is a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17. GO:0072538 T-helper 17 type immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072538 Th17 immune response An immune response which is associated with resistance to intracellular bacteria with a key role in inflammation and tissue injury. This immune response is associated with pathological autoimmune conditions such as multiple sclerosis, arthritis and psoriasis which is typically orchestrated by the production of particular cytokines by T-helper 17 cells, most notably interleukin-17, IL-21 and IL-22. GO:0072537 fibroblast activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072537 A change in the morphology or behavior of a fibroblast resulting from exposure to an activating factor such as a cellular or soluble ligand. GO:0072536 interleukin-23 receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0072536 IL-23 receptor complex A protein complex that binds interleukin-23 and that consists of, at a minimum, a dimeric interleukin and its two receptor subunits as well as optional additional kinase subunits. GO:0072535 tumor necrosis factor (ligand) superfamily member 11 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0072535 TNFSF11 production|RANKL production|tumor necrosis factor ligand superfamily member 11 production The appearance of tumor necrosis factor superfamily member 11 (TNFSF11; RANKL) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0072534 perineuronal net biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0072534 PNN A dense extracellular matrix (ECM) that forms around many neuronal cell bodies and dendrites late in development and is responsible for synaptic stabilization in the adult brain. GO:0072533 tri-(coumaroyl or caffeoyl) spermidine meta-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0072533 Catalysis of the meta-hydroxylation of any of the three phenolic rings on tricoumaroyl spermidine or any of its mono- or dicaffeoyl spermidine derivatives. GO:0072532 tri-(feruloyl or hydroxyferuloyl) spermidine meta-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0072532 Catalysis of the meta-hydroxylation of any of the three phenolic rings on triferuloyl spermidine or any of its mono- or di-(hydroxyferuloyl)-spermidine derivatives. GO:0072531 pyrimidine-containing compound transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072531 pyrimidine-containing compound membrane transport The process in which a pyrimidine-containing compound is transported across a membrane. A pyrimidine-containing compound is any compound that contains pyrimidine or a formal derivative thereof. GO:0072530 purine-containing compound transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072530 purine-containing compound membrane transport The process in which a purine-containing compound is transported across a membrane. A purine-containing compound is any compound that contains purine or a formal derivative thereof. GO:0047584 4-oxalmesaconate hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047584 KEGG_REACTION:R04478|EC:4.2.1.83|RHEA:17401|MetaCyc:RXN-2463 oxalmesaconate hydratase activity|4-carboxy-2-oxobutane-1,2,4-tricarboxylate 2,3-hydro-lyase activity|gamma-oxalmesaconate hydratase activity|4-carboxy-2-oxohexenedioate hydratase activity|2-hydroxy-4-oxobutane-1,2,4-tricarboxylate 2,3-hydro-lyase [(E)-4-oxobut-1-ene-1,2,4-tricarboxylate-forming]|2-hydroxy-4-oxobutane-1,2,4-tricarboxylate 2,3-hydro-lyase activity Catalysis of the reaction: 2-hydroxy-4-oxobutane-1,2,4-tricarboxylate = (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate + H(2)O. CHEBI:24610 homocysteines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24610 GO:0047583 4-methyloxaloacetate esterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047583 RHEA:10564|KEGG_REACTION:R01144|MetaCyc:4-METHYLOXALOACETATE-ESTERASE-RXN|EC:3.1.1.44 oxaloacetate-4-methyl-ester oxaloacetohydrolase activity Catalysis of the reaction: 4-methoxy-2,4-dioxobutanoate + H(2)O = H(+) + methanol + oxaloacetate. GO:0047582 4-methyleneglutaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047582 EC:3.5.1.67|RHEA:14741|MetaCyc:4-METHYLENEGLUTAMINASE-RXN|KEGG_REACTION:R02712 4-methyleneglutamine amidohydrolase activity|4-methylene-L-glutamine amidohydrolase activity|4-methyleneglutamine deamidase activity Catalysis of the reaction: 4-methylene-L-glutamine + H(2)O = 4-methylene-L-glutamate + NH(4)(+). GO:0047581 4-methyleneglutamate-ammonia ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047581 RHEA:13853|EC:6.3.1.7|MetaCyc:4-METHYLENEGLUTAMATE--AMMONIA-LIGASE-RXN|KEGG_REACTION:R02711 4-methyleneglutamine synthetase activity|4-methylene-L-glutamate:ammonia ligase (AMP-forming) Catalysis of the reaction: 4-methylene-L-glutamate + ATP + NH(4)(+) = 4-methylene-L-glutamine + AMP + diphosphate + 2 H(+). GO:0047580 4-hydroxyproline epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047580 EC:5.1.1.8|RHEA:21152|KEGG_REACTION:R03296|MetaCyc:4-HYDROXYPROLINE-EPIMERASE-RXN 4-hydroxyproline 2-epimerase activity|hydroxyproline epimerase activity|L-hydroxyproline epimerase activity|hydroxyproline 2-epimerase activity Catalysis of the reaction: trans-4-hydroxy-L-proline = cis-4-hydroxy-D-proline. CHEBI:24613 homodetic cyclic peptide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24613 CHEBI:24612 homocystines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24612 GO:0047589 5-aminovalerate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047589 EC:2.6.1.48|RHEA:10212|KEGG_REACTION:R02274|MetaCyc:VAGL-RXN 5-aminovalerate aminotransferase activity|delta-aminovalerate aminotransferase activity|delta-aminovalerate transaminase activity|5-aminopentanoate:2-oxoglutarate aminotransferase activity Catalysis of the reaction: 2-oxoglutarate + 5-aminopentanoate = 5-oxopentanoate + L-glutamate. GO:0047588 5-aminopentanamidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047588 MetaCyc:5-AMINOPENTANAMIDASE-RXN|EC:3.5.1.30|RHEA:15677 5-aminopentanamide amidohydrolase activity|5-aminovaleramidase activity|5-aminonorvaleramidase activity Catalysis of the reaction: 5-aminopentanamide + H2O = 5-aminopentanoate + NH3. GO:0047587 5-alpha-hydroxysteroid dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047587 KEGG_REACTION:R03675|EC:4.2.1.62|RHEA:22064|MetaCyc:5-ALPHA-HYDROXYSTEROID-DEHYDRATASE-RXN 5alpha-ergosta-7,22-diene-3beta,5-diol 5,6-hydro-lyase (ergosterol-forming)|5alpha-ergosta-7,22-diene-3beta,5-diol 5,6-hydro-lyase activity|5alpha-hydroxysteroid dehydratase activity Catalysis of the reaction: 5alpha-ergosta-7,22-diene-3beta,5-diol = ergosterol + H(2)O. GO:0047586 5'-acylphosphoadenosine hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047586 RHEA:16837|EC:3.6.1.20|MetaCyc:5-ACYLPHOSPHOADENOSINE-HYDROLASE-RXN 5-phosphoadenosine hydrolase activity|5'-acylphosphoadenosine acylhydrolase activity Catalysis of the reaction: 5'-acylphosphoadenosine + H2O = AMP + a carboxylate. GO:0047585 4-pyridoxolactonase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047585 KEGG_REACTION:R02992|RHEA:14301|MetaCyc:4-PYRIDOXOLACTONASE-RXN|EC:3.1.1.27 4-pyridoxolactone lactonohydrolase activity Catalysis of the reaction: 4-pyridoxolactone + H(2)O = 4-pyridoxate + H(+). GO:0072529 pyrimidine-containing compound catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072529 pyrimidine and derivative catabolic process|pyrimidine-containing compound degradation|pyrimidine-containing compound breakdown|pyrimidine-containing compound catabolism The chemical reactions and pathways resulting in the breakdown of a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof. GO:0072528 pyrimidine-containing compound biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072528 pyrimidine-containing compound biosynthesis|pyrimidine-containing compound anabolism|pyrimidine-containing compound synthesis|pyrimidine-containing compound formation|pyrimidine and derivative biosynthetic process The chemical reactions and pathways resulting in the formation of a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof. GO:0072527 pyrimidine-containing compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072527 pyrimidine-containing compound metabolism|pyrimidine and derivative metabolic process The chemical reactions and pathways involving a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof. GO:0072526 pyridine-containing compound catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072526 pyridine-containing compound catabolism|pyridine and derivative catabolic process|pyridine-containing compound degradation|pyridine-containing compound breakdown The chemical reactions and pathways resulting in the breakdown of a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof. GO:0072525 pyridine-containing compound biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072525 pyridine-containing compound anabolism|pyridine-containing compound biosynthesis|pyridine-containing compound synthesis|pyridine-containing compound formation|pyridine and derivative biosynthetic process The chemical reactions and pathways resulting in the formation of a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof. GO:0072524 pyridine-containing compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072524 pyridine-containing compound metabolism|pyridine and derivative metabolic process The chemical reactions and pathways involving a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof. GO:0072523 purine-containing compound catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072523 purine and derivative catabolic process|purine-containing compound catabolism|purine-containing compound degradation|purine-containing compound breakdown The chemical reactions and pathways resulting in the breakdown of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof. GO:0072522 purine-containing compound biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072522 purine-containing compound anabolism|purine-containing compound synthesis|purine-containing compound formation|purine and derivative biosynthetic process|purine-containing compound biosynthesis The chemical reactions and pathways resulting in the formation of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof. GO:0072521 purine-containing compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072521 purine-containing compound metabolism|purine and derivative metabolic process The chemical reactions and pathways involving a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof. GO:0072520 seminiferous tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072520 The reproductive developmental process whose specific outcome is the progression of the seminiferous tubule over time, from its formation to the mature structure. Seminiferous tubules are ducts located in the testicles, and are the specific location of meiosis, and the subsequent creation of gametes, namely spermatozoa. CHEBI:24619 homoserine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24619 GO:0047595 6-hydroxynicotinate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047595 MetaCyc:6-HYDROXYNICOTINATE-REDUCTASE-RXN|RHEA:17225|EC:1.3.7.1 HNA reductase activity|6-oxotetrahydronicotinate dehydrogenase activity|6-oxo-1,4,5,6-tetrahydronicotinate:ferredoxin oxidoreductase activity|1,4,5,6-tetrahydro-6-oxonicotinate:ferredoxin oxidoreductase activity|6-hydroxynicotinic reductase activity|6-oxotetrahydro-nicotinate dehydrogenase activity Catalysis of the reaction: 1,4,5,6-tetrahydro-6-oxonicotinate + oxidized ferredoxin = 6-hydroxynicotinate + reduced ferredoxin. GO:0072551 diferuloyl mono-(hydroxyferuloyl) spermidine meta-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0072551 Catalysis of the reaction: diferuloyl mono-(hydroxyferuloyl) spermidine + NADPH + O2 = monoferuloyl di-(hydroxyferuloyl) spermidine + NADP+ + H2O. GO:0072550 triferuloylspermidine meta-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0072550 MetaCyc:RXN-11262 triferuloyl spermidine meta-hydroxylase activity Catalysis of the reaction: triferuloyl spermidine + NADPH + O2 = diferuloyl mono-(hydroxyferuloyl) spermidine + NADP+ + H2O. GO:0047594 6-beta-hydroxyhyoscyamine epoxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047594 KEGG_REACTION:R03737|RHEA:12797|EC:1.14.20.13|MetaCyc:6-BETA-HYDROXYHYOSCYAMINE-EPOXIDASE-RXN 6beta-hydroxyhyoscyamine epoxidase activity|hydroxyhyoscyamine dioxygenase activity|(6S)-6-hydroxyhyoscyamine,2-oxoglutarate oxidoreductase (epoxide-forming) Catalysis of the reaction: (6S)-6-hydroxyhyoscyamine + 2-oxoglutarate + O(2) = CO(2) + H(2)O + H(+) + scopolamine + succinate. GO:0047593 6-acetylglucose deacetylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047593 MetaCyc:6-ACETYLGLUCOSE-DEACETYLASE-RXN|KEGG_REACTION:R00327|EC:3.1.1.33|RHEA:18485 6-O-acetylglucose deacetylase activity|6-acetyl-D-glucose acetylhydrolase activity Catalysis of the reaction: 6-acetyl-D-glucose + H(2)O = D-glucose + acetate + H(+). GO:0047592 5-pyridoxate dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047592 EC:1.14.12.5|MetaCyc:5-PYRIDOXATE-DIOXYGENASE-RXN|RHEA:11152|KEGG_REACTION:R04570 5-pyridoxate oxidase activity|5-pyridoxate,NADPH:oxygen oxidoreductase (decyclizing) Catalysis of the reaction: 5-pyridoxate + NADPH + O(2) = (2Z)-2-(acetamidomethylene)-3-(hydroxymethyl)succinate + NADP(+). GO:0047591 5-hydroxypentanoate CoA-transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047591 MetaCyc:5-HYDROXYPENTANOATE-COA-TRANSFERASE-RXN|EC:2.8.3.14|KEGG_REACTION:R04057|RHEA:23496 5-hydroxyvalerate coenzyme A transferase activity|acetyl-CoA:5-hydroxypentanoate CoA-transferase activity|5-hydroxyvalerate CoA-transferase activity Catalysis of the reaction: 5-hydroxypentanoate + acetyl-CoA = 5-hydroxy-pentanoyl-CoA + acetate. GO:0047590 5-dehydro-2-deoxygluconokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047590 MetaCyc:5-DEHYDRO-2-DEOXYGLUCONOKINASE-RXN|RHEA:13497|EC:2.7.1.92 DKH kinase activity|5-keto-2-deoxyglucono kinase (phosphorylating)|5-keto-2-deoxygluconokinase activity|ATP:5-dehydro-2-deoxy-D-gluconate 6-phosphotransferase activity Catalysis of the reaction: ATP + 5-dehydro-2-deoxy-D-gluconate = ADP + 6-phospho-5-dehydro-2-deoxy-D-gluconate. GO:0047599 8-oxocoformycin reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047599 KEGG_REACTION:R03667|MetaCyc:8-OXOCOFORMYCIN-REDUCTASE-RXN|RHEA:23168|EC:1.1.1.235 8-ketodeoxycoformycin reductase activity|coformycin:NADP+ 8-oxidoreductase activity Catalysis of the reaction: coformycin + NADP(+) = 8-oxocoformycin + 2 H(+) + NADPH. GO:0047598 7-dehydrocholesterol reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047598 MetaCyc:RXN66-323|Reactome:R-HSA-6807055|Reactome:R-HSA-196402|EC:1.3.1.21|RHEA:23984 sterol Delta(7)-reductase activity|cholesterol:NADP+ delta7-oxidoreductase activity|sterol delta7-reductase activity|7-DHC reductase activity Catalysis of the reaction: cholesterol + NADP+ = cholesta-5,7-dien-3-beta-ol + NADPH + H+. GO:0047597 6-oxocineole dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047597 EC:1.14.13.51|MetaCyc:6-OXOCINEOLE-DEHYDROGENASE-RXN|KEGG_REACTION:R02995|RHEA:24324 6-oxocineole oxygenase activity|6-oxocineole,NADPH:oxygen oxidoreductase activity Catalysis of the reaction: 6-oxocineole + H(+) + NADPH + O(2) = 1,6,6-trimethyl-2,7-dioxabicyclo[3.2.2]nonan-3-one + H(2)O + NADP(+). GO:0047596 6-methylsalicylate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047596 KEGG_REACTION:R03567|EC:4.1.1.52|RHEA:23112|MetaCyc:6-METHYLSALICYLATE-DECARBOXYLASE-RXN 6-methylsalicylic acid (2,6-cresotic acid) decarboxylase activity|6-methylsalicylate carboxy-lyase activity|6-methylsalicylate carboxy-lyase (3-cresol-forming)|6-MSA decarboxylase activity Catalysis of the reaction: 6-methylsalicylate + H(+) = 3-cresol + CO(2). NCBITaxon:1338369 Dipnotetrapodomorpha organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_1338369 GO:0072559 NLRP3 inflammasome complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0072559 NALP3 inflammasome complex A protein complex that consists of three components, NLRP3 (NALP3), PYCARD and caspase-1. It is activated upon exposure to whole pathogens, as well as a number of structurally diverse pathogen- and danger-associated molecular patterns (PAMPs and DAMPs) and environmental irritants. Whole pathogens demonstrated to activate the NLRP3 inflammasome complex include the fungi Candida albicans and Saccharomyces cerevisiae, bacteria that produce pore-forming toxins, including Listeria monocytogenes and Staphylococcus aureus, and viruses such as Sendai virus, adenovirus, and influenza virus. GO:0072558 NLRP1 inflammasome complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0072558 NALP1 inflammasome complex A protein complex that consists of two components, NLRP1 (NALP1) and caspase-1 or caspase-5. The exact mechanisms of NLRP1 activation remain obscure, but potassium ion efflux appears to be essential. GO:0072557 IPAF inflammasome complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0072557 A protein complex that consists of three components, IPAF, NAIP and caspase-1, and includes among its functions the sensing of flagellin derived from Legionella pneumophila, Salmonella typhimurium, Pseudomonas aeruginosa and Shigella flexneri. GO:0072556 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072556 GO:0072555 17-beta-ketosteroid reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0072555 17-beta-ketosteroid reductase (NADPH) activity|7beta-ketosteroid reductase activity Catalysis of the reaction: a 17-beta-ketosteroid + NADPH + H+ = a 17-beta-hydroxysteroid + NADP+. GO:0072554 blood vessel lumenization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072554 The process in which a developing blood vessel forms an endothelial lumen through which blood will flow. GO:0072553 terminal button organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072553 bouton organization|terminal button organisation|terminal bouton organization|presynaptic bouton organization|synaptic bouton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a terminal button. A terminal button is the terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. GO:0072552 monoferuloyl di-(hydroxyferuloyl) spermidine meta-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0072552 Catalysis of the reaction: monoferuloyl di-(hydroxyferuloyl) spermidine + NADPH + O2 = tri-(hydroxyferuloyl) spermidine + NADP+ + H2O. GO:0072540 T-helper 17 cell lineage commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072540 Th17 cell lineage commitment|Th17 fate commitment|T-helper 17 cell fate commitment The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 17 cell, a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17. GO:0072549 monocoumaroyl dicaffeoyl spermidine meta-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0072549 Catalysis of the reaction: monocoumaroyl dicaffeoyl spermidine + NADPH + O2 = tricaffeoyl spermidine + NADP+ + H2O. GO:0072548 dicoumaroyl monocaffeoyl spermidine meta-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0072548 Catalysis of the reaction: dicoumaroyl monocaffeoyl spermidine + NADPH + O2 = monocoumaroyl dicaffeoyl spermidine + NADP+ + H2O. GO:0072547 tricoumaroylspermidine meta-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0072547 MetaCyc:RXN-11260 tricoumaroyl spermidine meta-hydroxylase activity Catalysis of the reaction: tricoumaroyl spermidine + NADPH + O2 = dicoumaroyl monocaffeoyl spermidine + NADP+ + H2O. GO:0072546 EMC complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0072546 endoplasmic reticulum membrane protein complex|ER membrane protein complex A transmembrane protein complex located in the endoplasmic reticulum (ER) involved in the insertion of newly synthesized proteins in the membrane of the ER. In S. cerevisiae, it has six members: EMC1, EMC2, AIM27, EMC4, KRE27, and EMC6. GO:0072545 tyrosine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0072545 Tyr binding Interacting selectively and non-covalently with 2-amino-3-(4-hydroxyphenyl)propanoic acid. GO:0072544 L-DOPA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0072544 L-dopa binding Interacting selectively and non-covalently with L-DOPA, the modified amino acid (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid. GO:0072543 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072543 GO:0072542 protein phosphatase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0072542 protein phosphatase type 2A activator activity|protein phosphatase type 1 activator activity|protein phosphatase 2 activator activity Increases the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule. GO:0072541 peroxynitrite reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0072541 peroxynitritase activity Catalysis of the reaction: 2 R-SH + ONOO- = R-SS-R + NO2- + H2O. CHEBI:73533 N(6)-(dimethylallyl)adenosine 5'-diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73533 CHEBI:73532 N(6)-(dimethylallyl)adenosine 5'-triphosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73532 CHEBI:48578 radical scavenger biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48578 CHEBI:73534 (9Z,12Z)-octadecadien-1-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73534 CHEBI:73537 1,8-naphthyridine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73537 CHEBI:73536 O-ureido-L-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73536 CHEBI:73539 naphthyridine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73539 PR:000010413 macrophage migration inhibitory factor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000010413 L-dopachrome tautomerase|MIF|DER6|GIF|GLIF|MMIF|phenylpyruvate tautomerase|glycosylation-inhibiting factor|delayed early response protein 6|L-dopachrome isomerase A protein that is a translation product of the human MIF gene or a 1:1 ortholog thereof. PO:0020127 primary root biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0020127 tap root (exact)|一次根 (Japanese, exact)|raíz primaria (Spanish, exact) A root (PO:0009005) that develops directly from a seedling radicle (PO:0020127). PO:0020123 root cap biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0020123 根冠（＝kalyptra) (Japanese, exact)|rootcap (exact)|caliptra de la raíz (Spanish, exact) A portion of root parenchyma (PO:0025095) tissue that is part of the root tip (PO:0000025) and covers the root apical meristem (PO:0020147). PO:0020121 lateral root biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0020121 raíz lateral (Spanish, exact)|側根 (Japanese, exact) A root (PO:0009005) that develops from a lateral root primordium (PO:0000016) that is part of another root on the same plant. CHEBI:73544 wybutosine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73544 CHEBI:73543 7-[(3S)-3-amino-3-carboxypropyl]wyosine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73543 CHEBI:73546 grixazone A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73546 CHEBI:73548 grixazone B biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73548 CHEBI:73549 3-hydroxy-3-(4-hydroxyphenyl)propionyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73549 GO:0047702 beta-lysine 5,6-aminomutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047702 KEGG_REACTION:R03275|MetaCyc:BETA-LYSINE-56-AMINOMUTASE-RXN|RHEA:21736|EC:5.4.3.3 L-beta-lysine 5,6-aminomutase activity|beta-lysine mutase activity|b-lysine 5,6-aminomutase activity|(3S)-3,6-diaminohexanoate 5,6-aminomutase activity Catalysis of the reaction: (3S)-3,6-diaminohexanoate = (3S,5S)-3,5-diaminohexanoate. GO:0047701 beta-L-arabinosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047701 EC:3.2.1.88|MetaCyc:BETA-L-ARABINOSIDASE-RXN b-L-arabinosidase activity|vicianosidase activity|beta-L-arabinoside arabinohydrolase activity Catalysis of the reaction: H2O + a beta-L-arabinoside = L-arabinose + an alcohol. GO:0047700 beta-glucoside kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047700 MetaCyc:BETA-GLUCOSIDE-KINASE-RXN|RHEA:21944|EC:2.7.1.85 beta-D-glucoside kinase (phosphorylating)|ATP:cellobiose 6-phosphotransferase activity|b-glucoside kinase activity Catalysis of the reaction: ATP + cellobiose = ADP + 6-phospho-beta-D-glucosyl-(1,4)-D-glucose. CHEBI:48560 dopaminergic agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48560 CHEBI:48561 dopaminergic antagonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48561 CHEBI:48563 methylsulfanyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48563 GO:0047709 bis(2-ethylhexyl)phthalate esterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047709 EC:3.1.1.60|KEGG_REACTION:R04202|MetaCyc:BIS2-ETHYLHEXYLPHTHALATE-ESTERASE-RXN|RHEA:15529 bis(2-ethylhexyl)phthalate acylhydrolase activity|DEHP esterase activity Catalysis of the reaction: bis(2-ethylhexyl)phthalate + H(2)O = 2-ethylhexan-1-ol + 2-ethylhexyl phthalate + H(+). GO:0047708 biotinidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047708 Reactome:R-HSA-3076905|Reactome:R-HSA-3325540|RHEA:13081|Reactome:R-HSA-4167509|Reactome:R-HSA-4225086|MetaCyc:BIOTINIDASE-RXN|EC:3.5.1.12 biotin-amide amidohydrolase activity|amidohydrolase biotinidase activity Catalysis of the reaction: biotin amide + H2O = biotin + NH3. GO:0047707 biotin-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047707 RHEA:19681|MetaCyc:BIOTIN--COA-LIGASE-RXN|EC:6.2.1.11 biotin:CoA ligase (AMP-forming)|biotinyl-CoA synthetase activity|biotinyl coenzyme A synthetase activity|biotin CoA synthetase activity Catalysis of the reaction: ATP + biotin + CoA = AMP + diphosphate + biotinyl-CoA. GO:0047706 biochanin-A reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047706 RHEA:12817|EC:1.3.1.46|KEGG_REACTION:R02954|MetaCyc:BIOCHANIN-A-REDUCTASE-RXN dihydrobiochanin-A:NADP+ delta2-oxidoreductase activity Catalysis of the reaction: dihydrobiochanin A + NADP(+) = biochanin A + H(+) + NADPH. GO:0047705 bilirubin oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047705 KEGG_REACTION:R02394|EC:1.3.3.5|MetaCyc:BILIRUBIN-OXIDASE-RXN|RHEA:20980 bilirubin oxidase M-1|bilirubin:oxygen oxidoreductase activity Catalysis of the reaction: 2 bilirubin + O(2) = 2 biliverdin + 2 H(2)O. GO:0047704 bile-salt sulfotransferase activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0047704 RHEA:14013|EC:2.8.2.14|MetaCyc:BILE-SALT-SULFOTRANSFERASE-RXN bile acid sulfotransferase I activity|glycolithocholate sulfotransferase activity|bile salt:3'phosphoadenosine-5'-phosphosulfate:sulfotransferase activity|bile acid:3'-phosphoadenosine-5'-phosphosulfate sulfotransferase activity|bile-salt sulphotransferase activity|BAST I activity|3'-phosphoadenylyl-sulfate:glycolithocholate sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + taurolithocholate = adenosine 3',5'-bisphosphate + taurolithocholate sulfate. GO:0047703 beta-nitroacrylate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047703 RHEA:23892|MetaCyc:BETA-NITROACRYLATE-REDUCTASE-RXN|EC:1.3.1.16|KEGG_REACTION:R03900 b-nitroacrylate reductase activity|3-nitropropanoate:NADP+ oxidoreductase activity Catalysis of the reaction: 3-nitropropanoate + NADP(+) = 3-nitroacrylate + H(+) + NADPH. CHEBI:73542 N(1)-methylguanosine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73542 CHEBI:73541 organic heterobicyclic ring biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73541 CHEBI:73555 7-(3-amino-3-carboxypropyl)wyosine 5'-monophosphate zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73555 CHEBI:24588 hexose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24588 CHEBI:24587 hexosaminide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24587 CHEBI:73557 4-demethyl-7-(3-amino-3-carboxypropyl)wyosine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73557 CHEBI:24586 hexosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24586 CHEBI:73556 4-demethyl-7-(3-amino-3-carboxypropyl)wyosine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73556 CHEBI:24585 hexosamine sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24585 CHEBI:73559 4-demethyl-7-(3-amino-3-carboxypropyl)wyosine 5'-monophosphate zwitterion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73559 CHEBI:73558 D3 vitamins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73558 CHEBI:24589 monosaccharide sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24589 GO:0047713 galactitol 2-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047713 RHEA:20685|MetaCyc:GALACTITOL-2-DEHYDROGENASE-RXN|EC:1.1.1.16|KEGG_REACTION:R02928 Catalysis of the reaction: galactitol + NAD(+) = D-tagatose + H(+) + NADH. CHEBI:24580 hexenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24580 GO:0047712 Cypridina-luciferin 2-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047712 MetaCyc:CYPRIDINA-LUCIFERIN-2-MONOOXYGENASE-RXN|RHEA:22760|EC:1.13.12.6 Cypridina-luciferin:oxygen 2-oxidoreductase (decarboxylating)|Cypridina-type luciferase activity|luciferase activity|luciferase (Cypridina luciferin)|Cypridina luciferase activity Catalysis of the reaction: Cypridina luciferin + O2 = oxidized Cypridina luciferin + CO2 + light. GO:0047711 blasticidin-S deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047711 MetaCyc:BLASTICIDIN-S-DEAMINASE-RXN|RHEA:10148|EC:3.5.4.23 blasticidin-S aminohydrolase activity Catalysis of the reaction: blasticidin S + H2O = deaminohydroxyblasticidin S + NH3. GO:0047710 bis(5'-adenosyl)-triphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047710 MetaCyc:BIS5-ADENOSYL-TRIPHOSPHATASE-RXN|EC:3.6.1.29|KEGG_REACTION:R00187|RHEA:13893 AP3A hydrolase activity|AP3Aase activity|dinucleosidetriphosphatase activity|1-P,3-P-bis(5'-adenosyl)-triphosphate adenylohydrolase activity|diadenosine 5',5'''-P1,P3-triphosphate hydrolase activity|AP(3)Aase activity|diadenosine 5',5'''-P(1),P(3)-triphosphate hydrolase activity|diadenosine 5,5-P1,P3-triphosphatase activity|AP(3)A hydrolase activity|P1,P3-bis(5'-adenosyl)-triphosphate adenylohydrolase activity Catalysis of the reaction: P(1),P(3)-bis(5'-adenosyl) triphosphate + H(2)O = ADP + AMP + 2 H(+). CHEBI:48551 guanidino group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48551 CHEBI:24584 hexosamine phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24584 CHEBI:48550 EC 1.1.1.21 (aldehyde reductase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48550 CHEBI:24583 hexitol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24583 CHEBI:24582 hexitol phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24582 GO:0047719 indole 2,3-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047719 KEGG_REACTION:R02338|MetaCyc:INDOLE-23-DIOXYGENASE-RXN|RHEA:11212|EC:1.13.11.17 indole-oxygen 2,3-oxidoreductase (decyclizing)|indole oxidase activity|indole:oxygen 2,3-oxidoreductase (decyclizing)|IDO|indole:O2 oxidoreductase activity Catalysis of the reaction: indole + O(2) = 2-formamidobenzaldehyde. GO:0047718 indanol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047718 MetaCyc:INDANOL-DEHYDROGENASE-RXN|EC:1.1.1.112 indan-1-ol:NAD(P)+ 1-oxidoreductase activity Catalysis of the reaction: indan-1-ol + NAD(P)+ = indanone + NAD(P)H + H+. GO:0047717 imidazoleacetate 4-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047717 MetaCyc:IMIDAZOLEACETATE-4-MONOOXYGENASE-RXN|RHEA:19425|KEGG_REACTION:R04066|EC:1.14.13.5 4-imidazoleacetate,NADH:oxygen oxidoreductase (5-hydroxylating)|imidazoleacetate hydroxylase activity|imidazoleacetic monooxygenase activity|imidazoleacetic hydroxylase activity Catalysis of the reaction: H(+) + imidazol-4-ylacetate + NADH + O(2) = 5-hydroxyimidazole-4-acetate + H(2)O + NAD(+). GO:0047716 imidazole N-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047716 MetaCyc:IMIDAZOLE-N-ACETYLTRANSFERASE-RXN|RHEA:15813|KEGG_REACTION:R03621|EC:2.3.1.2 acetyl-CoA:imidazole N-acetyltransferase activity|imidazole acetyltransferase activity|imidazole acetylase activity Catalysis of the reaction: 1H-imidazole + acetyl-CoA = N-acetylimidazole + CoA. PO:0020108 suspensor biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0020108 suspensor (Spanish, exact)|胚柄 (Japanese, exact) An embryonic plant structure at the base of a plant embryo that develops from an embryonic basal cell and connects an embryo proper to the wall of a megagametophyte. GO:0047715 hypotaurocyamine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047715 KEGG_REACTION:R03939|MetaCyc:HYPOTAUROCYAMINE-KINASE-RXN|RHEA:24008|EC:2.7.3.6 ATP:hypotaurocyamine N-phosphotransferase activity Catalysis of the reaction: ATP + hypotaurocyamine = N(omega)-phosphohypotaurocyamine + ADP + 2 H(+). GO:0047714 galactolipase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047714 EC:3.1.1.26|RHEA:13189|MetaCyc:GALACTOLIPASE-RXN galactolipid lipase activity|galactolipid acylhydrolase activity|polygalactolipase activity|1,2-diacyl-3-beta-D-galactosyl-sn-glycerol acylhydrolase activity Catalysis of the reaction: 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + 2 H2O = 3-beta-D-galactosyl-sn-glycerol + 2 carboxylates. PO:0020102 portion of transmitting tissue biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0020102 transmitting tract (related)|porción del tejido de transmisión (Spanish, exact)|伝達組織の一部 (Japanese, exact)|Poaceae transmitting tissue (narrow) A portion of ground tissue (PO:0025059) in the style of a carpel through which a pollen tube grows; it connects a stigma and the inside of an ovary. PO:0020101 stomium biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0020101 Zea stomium (narrow)|stomia (exact, plural)|Poaceae stomium (narrow)|estomio (Spanish, exact)|口辺細胞 (Japanese, exact) A plant anatomical space that is a slit in an anther lobe formed from when a dehiscence zone dehisces. CHEBI:73550 4-demethyl-7-(3-amino-3-carboxypropyl)wyosine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73550 CHEBI:73553 7-(3-amino-3-carboxypropyl)wyosine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73553 CHEBI:73552 7-[(3S-amino)-3-carboxypropyl]wyosine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73552 CHEBI:48544 methanesulfonates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48544 CHEBI:24599 histidine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24599 CHEBI:48545 pentapeptide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48545 GO:0047724 inosine nucleosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047724 EC:3.2.2.2|MetaCyc:INOSINE-NUCLEOSIDASE-RXN|RHEA:16657 inosine-guanosine nucleosidase activity|inosinase activity|inosine ribohydrolase activity Catalysis of the reaction: inosine + H2O = D-ribose + hypoxanthine. CHEBI:24591 hexuronate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24591 GO:0047723 inosinate nucleosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047723 MetaCyc:INOSINATE-NUCLEOSIDASE-RXN|RHEA:20469|KEGG_REACTION:R01128|EC:3.2.2.12 5'-inosinate phosphoribohydrolase activity Catalysis of the reaction: H(2)O + IMP = D-ribose 5-phosphate + hypoxanthine. GO:0047722 indolelactate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047722 EC:1.1.1.110|MetaCyc:INDOLELACTATE-DEHYDROGENASE-RXN|KEGG_REACTION:R01971|RHEA:20133 indolelactate:NAD+ oxidoreductase activity|(indol-3-yl)lactate:NAD+ oxidoreductase activity|indole-3-lactate dehydrogenase activity Catalysis of the reaction: 3-(indol-3-yl)lactate + NAD(+) = 3-(indol-3-yl)pyruvate + H(+) + NADH. GO:0047721 indoleacetate-lysine synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047721 KEGG_REACTION:R03095|MetaCyc:INDOLEACETATE--LYSINE-LIGASE-RXN|RHEA:14857|EC:6.3.2.20 indoleacetate:L-lysine ligase (ADP-forming)|N-(indole-3-acetyl)-L-lysine synthetase activity|indoleacetate-lysine ligase activity|IAA-lysine synthetase activity|(indol-3-yl)acetate:L-lysine ligase (ADP-forming) Catalysis of the reaction: (indol-3-yl)acetate + L-lysine + ATP = N(6)-[(indole-3-yl)acetyl]-L-lysine + ADP + 2 H(+) + phosphate. GO:0047720 indoleacetaldoxime dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047720 EC:4.99.1.6|KEGG_REACTION:R04093|MetaCyc:RXN-1403|RHEA:23156 indole-3-acetaldoxime hydro-lyase activity|3-indoleacetaldoxime hydro-lyase activity|indole-3-acetaldehyde-oxime hydro-lyase activity|indoleacetaldoxime hydro-lyase activity|(indol-3-yl)acetaldehyde-oxime hydro-lyase activity|(indol-3-yl)acetaldehyde-oxime hydro-lyase [(indol-3-yl)acetonitrile-forming] Catalysis of the reaction: (indol-3-yl)acetaldehyde oxime = (indol-3-yl)acetonitrile + H(2)O. CHEBI:48540 beta-adrenergic drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48540 CHEBI:48542 deca-2,4,6,8-tetraenedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48542 CHEBI:24592 hexuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24592 GO:0047729 carnitine decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047729 MetaCyc:CARNITINE-DECARBOXYLASE-RXN|EC:4.1.1.42|RHEA:21576|KEGG_REACTION:R02398 carnitine carboxy-lyase activity|carnitine carboxy-lyase (2-methylcholine-forming) Catalysis of the reaction: carnitine + H(+) = 2-methylcholine + CO(2). GO:0047728 carnitine 3-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047728 EC:1.1.1.108|RHEA:19265|MetaCyc:CARNITINE-3-DEHYDROGENASE-RXN|KEGG_REACTION:R02395 carnitine:NAD+ 3-oxidoreductase activity Catalysis of the reaction: carnitine + NAD(+) = 3-dehydrocarnitine + H(+) + NADH. GO:0047727 isobutyryl-CoA mutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047727 RHEA:13141|KEGG_REACTION:R01181|EC:5.4.99.13|MetaCyc:ISOBUTYRYL-COA-MUTASE-RXN 2-methylpropanoyl-CoA CoA-carbonylmutase activity|isobutyryl coenzyme A mutase activity|butyryl-CoA:isobutyryl-CoA mutase activity Catalysis of the reaction: isobutyryl-CoA = butanoyl-CoA. GO:0047726 iron-cytochrome-c reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047726 EC:1.9.98.1|RHEA:15617|MetaCyc:IRON--CYTOCHROME-C-REDUCTASE-RXN iron-cytochrome c reductase activity|ferrocytochrome-c:Fe3+ oxidoreductase activity Catalysis of the reaction: ferrocytochrome c + Fe3+ = ferricytochrome c + Fe2+. GO:0047725 inulosucrase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047725 MetaCyc:INULOSUCRASE-RXN|RHEA:15745|EC:2.4.1.9 sucrose 1-fructosyl transferase activity|sucrose:2,1-beta-D-fructan 1-beta-D-fructosyltransferase activity|sucrose 1-fructosyltransferase activity Catalysis of the reaction: sucrose + 2,1-beta-D-fructosyl(n) = glucose + 2,1-beta-D-fructosyl(n+1). CHEBI:48536 amidopyrimidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48536 CHEBI:48539 alpha-adrenergic drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48539 CHEBI:24567 cyclohexane-1,2-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_24567 GO:0047735 cellobiose dehydrogenase (acceptor) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047735 MetaCyc:CELLOBIOSE-DEHYDROGENASE-ACCEPTOR-RXN|RHEA:23484|EC:1.1.99.18 cellobiose dehydrogenase (quinone) activity|cellobiose-quinone oxidoreductase activity|cellobiose:(acceptor) 1-oxidoreductase activity|phanerochaete chrysosporium cellobiose oxidoreductase activity|cellobiose:acceptor 1-oxidoreductase activity|cellobiose oxidase activity|cellobiose dehydrogenase activity|cellobiose:oxygen 1-oxidoreductase activity|CBOR activity|cellobiose oxidoreductase activity|CDH activity Catalysis of the reaction: cellobiose + acceptor = cellobiono-1,5-lactone + reduced acceptor. GO:0047734 CDP-glycerol diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047734 KEGG_REACTION:R00855|EC:3.6.1.16|RHEA:21692|MetaCyc:CDP-GLYCEROL-PYROPHOSPHATASE-RXN CDP-glycerol pyrophosphatase activity|cytidine diphosphoglycerol pyrophosphatase activity|CDPglycerol phosphoglycerohydrolase activity|CDPglycerol pyrophosphatase activity|CDPglycerol diphosphatase activity|CDP-glycerol phosphoglycerohydrolase activity Catalysis of the reaction: CDP-glycerol + H(2)O = sn-glycerol 3-phosphate + CMP + 2 H(+). GO:0047733 CDP-glucose 4,6-dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047733 EC:4.2.1.45|KEGG_REACTION:R02426|RHEA:17153|MetaCyc:CDP-GLUCOSE-46-DEHYDRATASE-RXN CDPglucose 4,6-hydro-lyase activity|CDP-glucose 4,6-hydro-lyase (CDP-4-dehydro-6-deoxy-D-glucose-forming)|cytidine diphosphoglucose oxidoreductase activity|CDP-glucose 4,6-hydro-lyase activity|CDPglucose 4,6-dehydratase activity Catalysis of the reaction: CDP-D-glucose = CDP-4-dehydro-6-deoxy-D-glucose + H(2)O. UBERON:0015757 heterogeneous tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015757 portion of heterogeneous tissue GO:0047732 CDP-abequose epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047732 RHEA:21656|EC:5.1.3.10|MetaCyc:RXN-9160|KEGG_REACTION:R04266 cytidine diphosphoparatose epimerase activity|CDP-paratose epimerase activity|CDP-tyvelose 2-epimerase activity|CDP-paratose 2-epimerase activity|cytidine diphosphoabequose epimerase activity|CDP-3,6-dideoxy-D-glucose 2-epimerase activity|cytidine diphosphodideoxyglucose epimerase activity|cytidine diphosphate paratose-2-epimerase activity|CDP-D-abequose 2-epimerase activity Catalysis of the reaction: CDP-3,6-dideoxy-D-glucose = CDP-3,6-dideoxy-D-mannose. GO:0047731 catechol oxidase (dimerizing) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047731 MetaCyc:CATECHOL-OXIDASE-DIMERIZING-RXN|RHEA:12809|EC:1.1.3.14 catechol:oxygen oxidoreductase (dimerizing) Catalysis of the reaction: 4 catechol + 3 O2 = 2 dibenzo[1,4]dioxin-2,3-dione + 6 H2O. GO:0047730 carnosine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047730 MetaCyc:CARNOSINE-SYNTHASE-RXN|EC:6.3.2.11|RHEA:19297|Reactome:R-HSA-6786245 carnosine synthetase activity|L-histidine:beta-alanine ligase (AMP-forming)|carnosine-anserine synthetase activity|carnosine-homocarnosine synthetase activity|homocarnosine-carnosine synthetase activity Catalysis of the reaction: ATP + L-histidine + beta-alanine = AMP + diphosphate + carnosine. CHEBI:24561 hexahydroxyflavone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24561 GO:0047739 cephalosporin-C deacetylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047739 MetaCyc:CEPHALOSPORIN-C-DEACETYLASE-RXN|EC:3.1.1.41|RHEA:22596|KEGG_REACTION:R03062 cephalosporin-C acetylhydrolase activity|cephalosporin C acetyl-esterase activity|cephalosporin C acetyl-hydrolase activity|cephalosporin C deacetylase activity|cephalosporin C acetylase activity|cephalosporin C acetylesterase activity|cephalosporin acetylesterase activity Catalysis of the reaction: cephalosporin C + H(2)O = acetate + deacetylcephalosporin C + H(+). GO:0047738 cellobiose phosphorylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047738 EC:2.4.1.20|RHEA:19493|MetaCyc:CELLOBIOSE-PHOSPHORYLASE-RXN cellobiose:phosphate alpha-D-glucosyltransferase activity Catalysis of the reaction: cellobiose + phosphate = alpha-D-glucose 1-phosphate + D-glucose. GO:0047737 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0047737 GO:0047736 cellobiose epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047736 EC:5.1.3.11|RHEA:23384|MetaCyc:CELLOBIOSE-EPIMERASE-RXN cellobiose 2-epimerase activity Catalysis of the reaction: cellobiose = D-glucosyl-D-mannose. UBERON:0001114 right lobe of liver biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001114 right hepatic lobe|liver right lobe|right liver lobe|gall bladder lobe|2nd lobe|lobus hepatis dexter|lobus hepaticus dexter|second lobe The right lobe is much larger than the left; the proportion between them being as six to one. It occupies the right hypochondrium, and is separated from the left lobe on its upper surface by the falciform ligament; on its under and posterior surfaces by the left sagittal fossa; and in front by the umbilical notch. It is of a somewhat quadrilateral form, its under and posterior surfaces being marked by three fossæ: the porta and the fossæ for the gall-bladder and inferior vena cava, which separate its left part into two smaller lobes; the quadrate and caudate lobes. [WP,unvetted]. UBERON:0001113 lobe of liver biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001113 hepatic lobe|liver lobe|lobus hepatis Traditional gross anatomy divided the liver into four lobes based on surface features. The falciform ligament is visible on the front (anterior side) of the liver. This divides the liver into a left anatomical lobe, and a right anatomical lobe. UBERON:0001115 left lobe of liver biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001115 liver left lobe|lobus hepaticus sinister|left hepatic lobe|left liver lobe|lobus hepatis sinister The left lobe is smaller and more flattened than the right. It is situated in the epigastric and left hypochondriac regions. Its upper surface is slightly convex and is moulded on to the diaphragm; its under surface presents the gastric impression and omental tuberosity. [WP,unvetted]. UBERON:0001112 latissimus dorsi muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001112 dorsal latissimus muscle|musculus latissimus dorsi|latissimi dorsi|musculus latissimus dorsi|latissimus dorsi The latissimus dorsi is the larger, flat, dorso-lateral muscle on the trunk, posterior to the arm, and partly covered by the trapezius on its median dorsal region. [WP,unvetted]. CHEBI:24577 hexaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24577 CHEBI:24576 hexaric acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24576 CHEBI:48526 hydratropic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48526 CHEBI:48527 (S)-hydratropic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48527 CHEBI:24578 hexenal biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24578 GO:0047746 chlorophyllase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047746 EC:3.1.1.14|MetaCyc:CHLOROPHYLLASE-RXN chlorophyll chlorophyllidohydrolase activity Catalysis of the reaction: chlorophyll + H2O = phytol + chlorophyllide. GO:0047745 chlorogenate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047745 MetaCyc:CHLOROGENATE-HYDROLASE-RXN|RHEA:20689|EC:3.1.1.42|KEGG_REACTION:R02997 chlorogenic acid esterase activity|chlorogenase activity Catalysis of the reaction: chlorogenate + H(2)O = (-)-quinate + cis-caffeate + H(+). GO:0047744 chloridazon-catechol dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047744 EC:1.13.11.36|RHEA:20449|MetaCyc:CHLORIDAZON-CATECHOL-DIOXYGENASE-RXN|KEGG_REACTION:R04602 5-amino-4-chloro-2-(2,3-dihydroxyphenyl)-3(2H)-pyridazinone 1,2-oxidoreductase (decyclizing) Catalysis of the reaction: 5-amino-4-chloro-2-(2,3-dihydroxyphenyl)pyridazin-3(2H)-one + O(2) = 5-amino-4-chloro-2-(2-hydroxymuconoyl)pyridazin-3(2H)-one + 2 H(+). GO:0047743 chlordecone reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047743 KEGG_REACTION:R03716|RHEA:14401|MetaCyc:CHLORDECONE-REDUCTASE-RXN|EC:1.1.1.225 chlordecone-alcohol:NADP+ 2-oxidoreductase activity|CDR activity Catalysis of the reaction: chlordecone alcohol + NADP(+) = chlordecone + H(+) + NADPH. GO:0047742 chenodeoxycholoyltaurine hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047742 MetaCyc:CHENODEOXYCHOLOYLTAURINE-HYDROLASE-RXN|RHEA:16309|EC:3.5.1.74 chenodeoxycholoyltaurine amidohydrolase activity Catalysis of the reaction: chenodeoxycholoyltaurine + H2O = chenodeoxycholate + taurine. CHEBI:24573 hexanone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24573 GO:0047741 cetraxate benzylesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047741 KEGG_REACTION:R03612|EC:3.1.1.70|RHEA:23460|MetaCyc:CETRAXATE-BENZYLESTERASE-RXN cetraxate-benzyl-ester benzylhydrolase activity Catalysis of the reaction: benzyl cetraxate + H(2)O = benzyl alcohol + cetraxate + H(+). GO:0047740 cephalosporin-C transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047740 MetaCyc:CEPHALOSPORIN-C-TRANSAMINASE-RXN|EC:2.6.1.74|RHEA:14553|KEGG_REACTION:R03063 L-alanine:cephalosporin-C aminotransferase activity|cephalosporin C aminotransferase activity|cephalosporin-C:2-oxoglutarate aminotransferase activity Catalysis of the reaction: (7R)-7-(5-carboxylato-5-oxopentanamido)deacetylcephalosporanate + D-glutamate = 2-oxoglutarate + cephalosporin C. GO:0047749 cholestanetriol 26-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047749 EC:1.14.15.15|MetaCyc:CHOLESTANETRIOL-26-MONOOXYGENASE-RXN|RHEA:14373 cytochrome P450 27A1' activity|5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 26-hydroxylase activity|cholesterol 27-hydroxylase activity|CYP27A|sterol 27-hydroxylase activity|sterol 26-hydroxylase activity|5beta-cholestane-3alpha,7alpha,12alpha-triol 26-hydroxylase activity|5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol hydroxylase activity|5beta-cholestane-3alpha,7alpha,12alpha-triol,NADPH:oxygen oxidoreductase (26-hydroxylating)|CYP27A1|cholestanetriol 26-hydroxylase activity|5beta-cholestane-3alpha,7alpha,12alpha-triol hydroxylase activity Catalysis of the reaction: 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol + NADPH + O2 = 5-beta-cholestane-3-alpha,7-alpha,12-alpha,26-tetraol + NADP+ + H2O. GO:0047748 cholestanetetraol 26-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047748 RHEA:34631|MetaCyc:CHOLESTANETETRAOL-26-DEHYDROGENASE-RXN 5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol dehydrogenase activity|TEHC-NAD oxidoreductase activity|5beta-cholestane-3alpha,7alpha,12alpha,26-tetraol:NAD+ 26-oxidoreductase activity|cholestanetetrol 26-dehydrogenase activity Catalysis of the reaction: 5-beta-cholestane-3-alpha,7-alpha,12-alpha,26-tetraol + NAD+ = 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestan-26-al + NADH. GO:0047747 cholate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047747 MetaCyc:CHOLATE--COA-LIGASE-RXN|EC:6.2.1.7 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate-CoA ligase activity|3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate-CoA synthetase activity|3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl coenzyme A synthetase activity|trihydroxycoprostanoyl-CoA synthetase activity|3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate-CoA ligase activity|cholyl-CoA synthetase activity|3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate-CoA ligase activity|cholate thiokinase activity|BAL activity|cholic acid:CoA ligase activity|THCA-CoA ligase activity|cholate:CoA ligase (AMP-forming)|bile acid CoA ligase activity|3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoate-CoA synthetase activity|bile acid coenzyme A ligase activity|3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl coenzyme A synthetase activity|3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoate-CoA ligase activity|choloyl coenzyme A synthetase activity|3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate:CoA ligase (AMP-forming) activity|choloyl-CoA synthetase activity|3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate:CoA ligase (AMP-forming)|cholic thiokinase activity|3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate--CoA ligase activity Catalysis of the reactions: (1) ATP + cholate + CoA = AMP + diphosphate + choloyl-CoA and (2) ATP + (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + CoA = AMP + diphosphate + (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA. UBERON:0001103 diaphragm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001103 diaphragm muscle|diaphragm of thorax|phren|thoracic diaphragm|midriff A thin musculomebranous barrier that separates the abdominal and thoracic cavities. Often used for breathing control CHEBI:48529 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48529 UBERON:0001105 clavicle bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001105 clavicula|clavicle|collar bone|collarbone A paired dermal or endochondral bone that is part of the pectoral girdle. The clavicle may be in contact with the interclavicle or coracoid and forms an attachment site for pectoral musculature. [PHENOSCAPE:ad]. CHEBI:73599 3-methylthioaspartate residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73599 CHEBI:48513 carbazoles biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48513 CHEBI:24548 hexadecenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24548 CHEBI:24547 hexadecenal biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24547 CHEBI:48517 7H-xanthine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48517 CHEBI:24546 hexadecen-1-ol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24546 CHEBI:24545 hexadecatrienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24545 GO:0047757 chondroitin-glucuronate 5-epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047757 RHEA:21084|Reactome:R-HSA-2022052|MetaCyc:CHONDROITIN-GLUCURONATE-5-EPIMERASE-RXN|EC:5.1.3.19 polyglucuronate 5-epimerase activity|chondroitin-D-glucuronate 5-epimerase activity|chondroitin D-glucuronosyl 5-epimerase activity|dermatan-sulfate 5-epimerase activity|urunosyl C-5 epimerase activity Catalysis of the reaction: chondroitin D-glucuronate = dermatan L-iduronate. GO:0047756 chondroitin 4-sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047756 EC:2.8.2.5|RHEA:16101|MetaCyc:CHONDROITIN-4-SULFOTRANSFERASE-RXN|Reactome:R-HSA-1971483 chondroitin 4-sulphotransferase activity|3'-phosphoadenylyl-sulfate:chondroitin 4'-sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 4'-sulfate. GO:0047755 isocitrate epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047755 RHEA:10820|EC:5.1.2.6|MetaCyc:ISOCITRATE-EPIMERASE-RXN|KEGG_REACTION:R02318 (1R,2S)-1-hydroxypropane-1,2,3-tricarboxylate 1-epimerase activity Catalysis of the reaction: D-threo-isocitrate = D-erythro-isocitrate. GO:0047754 choline sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047754 RHEA:21984|KEGG_REACTION:R01027|EC:2.8.2.6|MetaCyc:CHOLINE-SULFOTRANSFERASE-RXN choline sulphokinase activity|3'-phosphoadenylyl-sulfate:choline sulfotransferase activity|choline sulphotransferase activity Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + choline = adenosine 3',5'-diphosphate + choline sulfate + H(+). GO:0047753 choline-sulfatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047753 EC:3.1.6.6|MetaCyc:CHOLINE-SULFATASE-RXN|RHEA:20820|KEGG_REACTION:R01028 choline-sulphatase activity|choline-sulfate sulfohydrolase activity Catalysis of the reaction: choline sulfate + H(2)O = choline + H(+) + sulfate. GO:0047752 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0047752 GO:0047751 cholestenone 5-alpha-reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047751 KEGG_REACTION:R02610|RHEA:24552|EC:1.3.1.22|MetaCyc:CHOLESTENONE-5-ALPHA-REDUCTASE-RXN reduced nicotinamide adenine dinucleotide phosphate:Delta4-3-ketosteroid 5alpha-oxidoreductase activity|cholestenone 5a-reductase activity|4-ene-3-oxosteroid 5alpha-reductase activity|cholestenone 5alpha-reductase activity|3-oxosteroid delta4-dehydrogenase|4-ene-5alpha-reductase activity|testosterone delta4-5alpha-reductase activity|testosterone delta4-hydrogenase activity|3-oxosteroid 5alpha-reductase activity|3-oxo-5alpha-steroid:NADP+ delta4-oxidoreductase activity|cholest-4-en-3-one 5alpha-reductase activity|delta4-3-ketosteroid 5alpha-oxidoreductase activity|steroid 5alpha-hydrogenase activity|testosterone 5alpha-reductase|steroid 5alpha-reductase|5alpha-reductase Catalysis of the reaction: 5alpha-cholestan-3-one + NADP(+) = cholest-4-en-3-one + H(+) + NADPH. GO:0047750 cholestenol delta-isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047750 EC:5.3.3.5|RHEA:15281|MetaCyc:RXN66-25 delta7-cholestenol delta7-delta8-isomerase activity|cholestenol D-isomerase activity Catalysis of the reaction: 5-alpha-cholest-7-en-3-beta-ol = 5-alpha-cholest-8-en-3-beta-ol. GO:0072719 cellular response to cisplatin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072719 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cisplatin stimulus. GO:0072718 response to cisplatin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072718 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cisplatin stimulus. GO:0072717 cellular response to actinomycin D biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072717 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an actinomycin D stimulus. PO:0020149 quiescent center biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0020149 centro de division de células del meristema (Spanish, exact)|静止中心 (Japanese, exact) A portion of meristem tissue (PO:0009013) that is part of a root apical meristem (PO:0020147) and consists of mitotically and metabolically inactive cells and is located behind the protoderm (PO:0006210) of the root (PO:0009005). GO:0072716 response to actinomycin D biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072716 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an actinomycin D stimulus. GO:0072715 cellular response to selenite ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072715 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a selenite ion stimulus. GO:0047759 butanal dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047759 MetaCyc:BUTANAL-DEHYDROGENASE-RXN|EC:1.2.1.57 butanal:NAD(P)+ oxidoreductase (CoA-acylating) Catalysis of the reaction: butanal + CoA + NAD(P)+ = butanoyl-CoA + NAD(P)H + H+. GO:0047758 ATP:2-methylpropanoate phosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047758 EC:2.7.2.14|RHEA:24156|KEGG_REACTION:R04002|MetaCyc:BRANCHED-CHAIN-FATTY-ACID-KINASE-RXN ATP:2-methylpropanoate 1-phosphotransferase activity|branched-chain fatty acid kinase activity|branched-chain-fatty-acid kinase activity|ATP:isobutyrate 1-phosphotransferase activity|ATP:branched-chain-fatty-acid 1-phosphotransferase activity|isobutyrate kinase activity|ATP:2-methylpropanoate kinase activity Catalysis of the reaction: 2-methylpropanoate + ATP = 2-methylpropanoyl phosphate + ADP + H(+). GO:0072714 response to selenite ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072714 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a selenite ion stimulus. GO:0072713 cellular response to thiabendazole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072713 cellular response to TBZ Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thiabendazole stimulus. GO:0072712 response to thiabendazole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072712 response to TBZ Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thiabendazole stimulus. PO:0020148 shoot apical meristem biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0020148 SAM (exact)|meristema apical del epiblasto (epiblastema) (Spanish, exact)|promeristem (broad)|primary shoot meristem (related)|茎頂分裂組織 (Japanese, exact) A shoot system meristem (PO:0006079) formed at the apex of the shoot axis (PO:0025029), including those originating from an axillary bud meristem (PO:0000232). GO:0072711 cellular response to hydroxyurea biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072711 cellular response to HU Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyurea stimulus. PO:0020147 root apical meristem biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0020147 RAM (exact)|promeristem (broad)|meristema apical de la raíz (Spanish, exact)|根端分裂組織 (Japanese, exact) A root meristem (PO:0006085) located at the root tip (PO:0000025), behind the root cap (PO:0020123). GO:0072710 response to hydroxyurea biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072710 response to HU Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyurea stimulus. CHEBI:24549 hexadecenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24549 PO:0020144 apical meristem biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0020144 頂端分裂組織 (Japanese, exact)|promeristem (broad)|meristema apical (Spanish, exact)|AM (exact)|primary meristem (related) A maximal portion of meristem tissue (PO:0009013) located at a shoot apex (PO:0000037) or root tip (PO:0000025). GO:0047760 butyrate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047760 Reactome:R-HSA-8875013|RHEA:24336|MetaCyc:BUTYRATE--COA-LIGASE-RXN|EC:6.2.1.2 butyryl-coenzyme A synthetase activity|short-chain acyl-CoA synthetase activity|fatty acid activating enzyme|medium chain acyl-CoA synthetase activity|fatty acid thiokinase (medium chain) activity|fatty acyl coenzyme A synthetase activity|butyryl-CoA synthetase activity|butanoate:CoA ligase (AMP-forming)|L-(+)-3-hydroxybutyryl CoA ligase activity|acyl-activating enzyme activity Catalysis of the reaction: ATP + an acid + CoA = AMP + diphosphate + an acyl-CoA. CHEBI:24555 hexadienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24555 CHEBI:24554 hexadienoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24554 CHEBI:24553 hexadienedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24553 CHEBI:24552 hexadienedioate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24552 GO:0047768 carboxy-cis,cis-muconate cyclase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047768 KEGG_REACTION:R03308|RHEA:14977|EC:5.5.1.5|MetaCyc:CARBOXY-CISCIS-MUCONATE-CYCLASE-RXN 3-carboxymuconate cyclase activity|3-carboxy-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing)|3-carboxy-cis,cis-muconate lactonizing enzyme activity Catalysis of the reaction: 3-carboxy-2,5-dihydro-5-oxofuran-2-acetate = 3-carboxy-cis,cis-muconate. GO:0047767 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0047767 GO:0047766 carbamoyl-serine ammonia-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047766 MetaCyc:CARBAMOYL-SERINE-AMMONIA-LYASE-RXN|EC:4.3.1.13|KEGG_REACTION:R00213|RHEA:15445 O-carbamoyl-L-serine ammonia-lyase (pyruvate-forming)|O-carbamoyl-L-serine deaminase activity|carbamoylserine deaminase activity|O-carbamoyl-L-serine ammonia-lyase (decarboxylating; pyruvate-forming) Catalysis of the reaction: O-carbamoyl-L-serine + H(2)O + H(+) = CO(2) + 2 NH(4)(+) + pyruvate. GO:0047765 caldesmon-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047765 MetaCyc:CALDESMON-PHOSPHATASE-RXN|EC:3.1.3.55 smooth muscle caldesmon phosphatase activity|SMP-I|caldesmon-phosphate phosphohydrolase activity Catalysis of the reaction: caldesmon phosphate + H2O = caldesmon + phosphate. CHEBI:24551 hexadienal biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24551 GO:0047764 obsolete caldesmon kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047764 MetaCyc:2.7.11.17-RXN OBSOLETE. Catalysis of the reaction: ATP + caldesmon = ADP + caldesmon phosphate. GO:0047763 caffeate O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047763 MetaCyc:RXN-1104|EC:2.1.1.68|RHEA:20225 caffeate methyltransferase activity|S-adenosyl-L-methionine:3,4-dihydroxy-trans-cinnamate 3-O-methyltransferase activity|caffeate 3-O-methyltransferase activity|S-adenosyl-L-methionine:caffeic acid-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 3,4-dihydroxy-trans-cinnamate = S-adenosyl-L-homocysteine + 3-methoxy-4-hydroxy-trans-cinnamate. GO:0047762 caffeate 3,4-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047762 EC:1.13.11.22|RHEA:22216|MetaCyc:CAFFEATE-34-DIOXYGENASE-RXN|KEGG_REACTION:R03365 3,4-dihydroxy-trans-cinnamate:oxygen 3,4-oxidoreductase (decyclizing) Catalysis of the reaction: trans-caffeate + O(2) = 3-(2-carboxyethenyl)-cis,cis-muconate + 2 H(+). GO:0047761 butyrate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047761 KEGG_REACTION:R01688|EC:2.7.2.7|RHEA:13585|MetaCyc:BUTYRATE-KINASE-RXN ATP:butanoate 1-phosphotransferase activity Catalysis of the reaction: ATP + butanoate = ADP + butanoyl phosphate + H(+). GO:0072709 cellular response to sorbitol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072709 cellular response to glucitol Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sorbitol stimulus. GO:0072708 response to sorbitol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072708 response to glucitol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sorbitol stimulus. GO:0072707 cellular response to sodium dodecyl sulfate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072707 cellular response to SDS Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium dodecyl sulfate (SDS) stimulus. GO:0072706 response to sodium dodecyl sulfate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072706 response to SDS Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium dodecyl sulfate (SDS) stimulus. GO:0072705 cellular response to mercaptoethanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072705 cellular response to 2-sulfanylethanol Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercaptoethanol stimulus. GO:0072704 response to mercaptoethanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072704 response to 2-sulfanylethanol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercaptoethanol stimulus. UBERON:0015717 smooth muscle tissue layer of ejaculatory duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015717 muscle layer of ejaculatory duct A smooth muscle tissue that is part of a ejaculatory duct. GO:0072703 cellular response to methyl methanesulfonate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072703 cellular response to MMS Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methyl methanesulfonate (MMS) stimulus. GO:0047769 arogenate dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047769 MetaCyc:CARBOXYCYCLOHEXADIENYL-DEHYDRATASE-RXN|RHEA:12536|EC:4.2.1.91 L-arogenate hydro-lyase (decarboxylating)|carboxycyclohexadienyl dehydratase activity|L-arogenate hydro-lyase (decarboxylating; L-phenylalanine-forming) Catalysis of the reaction: L-arogenate = L-phenylalanine + H2O + CO2. PR:000010444 mitogen-activated protein kinase kinase kinase 21 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000010444 MAP3K21|mixed lineage kinase 4|MLK4|mitogen-activated protein kinase kinase kinase MLK4 A protein that is a translation product of the human MAP3K21 gene or a 1:1 ortholog thereof. UBERON:0015716 anal canal epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015716 anal canal epithelium|epithelium of anal canal A epithelium that is part of a anal canal. GO:0072702 response to methyl methanesulfonate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072702 response to MMS Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methyl methanesulfonate (MMS) stimulus. GO:0072701 cellular response to bismuth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072701 cellular response to bismuth ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bismuth (Bi) stimulus. GO:0072700 response to bismuth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072700 response to bismuth ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bismuth (Bi) stimulus. GO:0033129 positive regulation of histone phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033129 Any process that activates or increases the frequency, rate or extent of the addition of one or more phosphate groups to a histone protein. GO:0033128 negative regulation of histone phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033128 Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of one or more phosphate groups to a histone protein. GO:0008169 C-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008169 EC:2.1.1.- Catalysis of the transfer of a methyl group to the carbon atom of an acceptor molecule. GO:0008168 methyltransferase activity biolink:MolecularActivity go-plus goslim_drosophila|goslim_generic|goslim_chembl|goslim_yeast http://purl.obolibrary.org/obo/GO_0008168 EC:2.1.1.-|Reactome:R-HSA-379387|Reactome:R-HSA-71286|Reactome:R-HSA-6800149|Reactome:R-HSA-212269|Reactome:R-HSA-379464 methylase Catalysis of the transfer of a methyl group to an acceptor molecule. GO:0008167 obsolete sigma virus replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008167 sigma virus replication OBSOLETE. (Was not defined before being made obsolete). GO:0008166 obsolete viral replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008166 viral replication OBSOLETE. (Was not defined before being made obsolete). GO:0008165 obsolete pyrethroid resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008165 pyrethroid resistance OBSOLETE. (Was not defined before being made obsolete). GO:0008164 obsolete organophosphorus resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008164 organophosphorus resistance OBSOLETE. (Was not defined before being made obsolete). GO:0008174 mRNA methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008174 Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an mRNA molecule. GO:0008173 RNA methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008173 Reactome:R-HSA-191784 Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in an RNA molecule. GO:0008172 S-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008172 Reactome:R-HSA-209821|EC:2.1.1.- Catalysis of the transfer of a methyl group to the sulfur atom of an acceptor molecule. GO:0008171 O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008171 Reactome:R-HSA-5629203|Reactome:R-HSA-5629237|Reactome:R-HSA-6790907|Reactome:R-HSA-5578717|EC:2.1.1.-|Reactome:R-HSA-5629218 Catalysis of the transfer of a methyl group to the oxygen atom of an acceptor molecule. GO:0008170 N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008170 EC:2.1.1.- Catalysis of the transfer of a methyl group to the nitrogen atom of an acceptor molecule. GO:0033127 regulation of histone phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033127 Any process that modulates the frequency, rate or extent of the addition of one or more phosphate groups to a histone protein. GO:0033126 obsolete positive regulation of GTP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033126 positive regulation of GTP degradation|positive regulation of GTP breakdown|positive regulation of GTP catabolism OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of GTP, guanosine triphosphate. GO:0033125 obsolete negative regulation of GTP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033125 negative regulation of GTP degradation|negative regulation of GTP catabolism|negative regulation of GTP breakdown OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of GTP, guanosine triphosphate. GO:0033124 obsolete regulation of GTP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033124 regulation of GTP catabolism|regulation of GTP degradation|regulation of GTP breakdown OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of GTP, guanosine triphosphate. GO:0033123 positive regulation of purine nucleotide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033123 positive regulation of purine nucleotide catabolism|positive regulation of purine nucleotide degradation|positive regulation of purine nucleotide breakdown Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides. GO:0033122 negative regulation of purine nucleotide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033122 negative regulation of purine nucleotide degradation|negative regulation of purine nucleotide breakdown|negative regulation of purine nucleotide catabolism Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides. GO:0033121 regulation of purine nucleotide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033121 regulation of purine nucleotide breakdown|regulation of purine nucleotide catabolism|regulation of purine nucleotide degradation Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides. GO:0033120 positive regulation of RNA splicing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033120 Any process that activates or increases the frequency, rate or extent of RNA splicing. GO:0033119 negative regulation of RNA splicing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033119 Any process that stops, prevents, or reduces the frequency, rate or extent of RNA splicing. GO:0033118 esterosome membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033118 The lipid bilayer surrounding an esterosome. This membrane has characteristics of rough endoplasmic reticulum (RER) membranes. GO:0033117 esterosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033117 A vesicle filled with crystalline protein that shows sequence similarities with various esterases. GO:0008179 adenylate cyclase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008179 Reactome:R-HSA-170672 adenylyl cyclase binding Interacting selectively and non-covalently with the enzyme adenylate cyclase. GO:0008178 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008178 GO:0008177 succinate dehydrogenase (ubiquinone) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008177 RHEA:13713|MetaCyc:SUCCINATE-DEHYDROGENASE-UBIQUINONE-RXN|KEGG_REACTION:R02164|EC:1.3.5.1|Reactome:R-HSA-70994|Reactome:R-HSA-163213 respiratory complex II|succinate dehydrogenase complex (i. e. SDH, involved in aerobic respiration, repressed in anaerobic respiration)|menaquinol: fumarate oxidoreductase activity|succinic dehydrogenase activity|fumarate reductase complex (i.e. FRD, involved in anaerobic respiration, repressed in aerobic respiration)|succinate:ubiquinone oxidoreductase activity|quinol:fumarate oxidoreductase activity Catalysis of the reaction: succinate + ubiquinone = fumarate + ubiquinol. GO:0008176 tRNA (guanine-N7-)-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008176 MetaCyc:TRNA-GUANINE-N7--METHYLTRANSFERASE-RXN|Reactome:R-HSA-6782286|RHEA:42708|EC:2.1.1.33 7-methylguanine transfer ribonucleate methylase activity|S-adenosyl-L-methionine:tRNA (guanine-N7-)-methyltransferase activity|tRNA guanine 7-methyltransferase activity|S-adenosyl-L-methionine:tRNA (guanine-7-N-)-methyltransferase activity|transfer ribonucleate guanine 7-methyltransferase activity|N7-methylguanine methylase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N7-methylguanine. GO:0008175 tRNA methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008175 Reactome:R-HSA-6783473|Reactome:R-HSA-6782881|Reactome:R-HSA-6782890|Reactome:R-HSA-6786567|Reactome:R-HSA-6786500|Reactome:R-HSA-6782879 Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in a tRNA molecule. GO:0008185 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008185 GO:0008184 glycogen phosphorylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008184 MetaCyc:GLYCOPHOSPHORYL-RXN|Reactome:R-HSA-453339|Reactome:R-HSA-453358|Reactome:R-HSA-71590|Reactome:R-HSA-71515 Catalysis of the reaction: glycogen + phosphate = maltodextrin + alpha-D-glucose 1-phosphate. GO:0008183 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008183 GO:0008182 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008182 GO:0008181 obsolete tumor suppressor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008181 tumor suppressor OBSOLETE. (Was not defined before being made obsolete). GO:0008180 COP9 signalosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0008180 COP9 complex|signalosome|CSN A protein complex that catalyzes the deneddylation of proteins, including the cullin component of SCF ubiquitin E3 ligase; deneddylation increases the activity of cullin family ubiquitin ligases. The signalosome is involved in many regulatory process, including some which control development, in many species; also regulates photomorphogenesis in plants; in many species its subunits are highly similar to those of the proteasome. GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033116 ER-Golgi intermediate compartment membrane The lipid bilayer surrounding any of the compartments of the endoplasmic reticulum (ER)-Golgi intermediate compartment system. GO:0033115 cyanelle thylakoid membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033115 The lipid bilayer membrane of any thylakoid within a cyanelle. GO:0033114 cyanelle thylakoid lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033114 The volume enclosed by a cyanelle thylakoid membrane. GO:0033113 cyanelle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033113 Either of the lipid bilayers that surround a cyanelle and form the cyanelle envelope. GO:0033112 cyanelle envelope biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033112 The double lipid bilayer enclosing the cyanelle and separating its contents from the rest of the cytoplasm; includes the intermembrane space. GO:0033111 attachment organelle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033111 The lipid bilayer surrounding an attachment organelle. This is a region of the cell membrane facing the environment - in mycoplasma, part of the mycolate outer membrane. GO:0033110 Cvt vesicle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033110 cytoplasm to vacuole targeting vesicle membrane|cytoplasm-to-vacuole targeting vesicle membrane Either of the two lipid bilayers surrounding a Cvt vesicle, a vesicle that functions in the cytoplasm-to-vacuole targeting (Cvt) pathway. GO:0033109 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0033109 GO:0033108 mitochondrial respiratory chain complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033108 The aggregation, arrangement and bonding together of a set of components to form a mitochondrial respiratory chain complex. GO:0033107 Cvt vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033107 cytoplasm to vacuole targeting vesicle|cytoplasm-to-vacuole targeting vesicle A cytosolic vesicle that is enclosed by a double membrane and is implicated in the cytoplasm to vacuole targeting pathway. These vesicles are found in the yeast S. cerevisiae, and contain vacuolar hydrolases, aminopeptidase I (Ape1p) and alpha-mannosidase (Ams1p). GO:0033106 cis-Golgi network membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033106 cis Golgi network membrane|Golgi cis face membrane The lipid bilayer surrounding any of the compartments that make up the cis-Golgi network. GO:0008149 obsolete para-aminobenzoic acid (PABA) synthase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008149 para-aminobenzoic acid (PABA) synthase OBSOLETE. (Was not defined before being made obsolete). GO:0008148 obsolete negative transcription elongation factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008148 negative transcription elongation factor activity OBSOLETE. Any activity that decreases the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule following transcription initiation. GO:0008147 structural constituent of bone biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008147 The action of a molecule that contributes to the structural integrity of bone. GO:0008146 sulfotransferase activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0008146 EC:2.8.2.-|Reactome:R-HSA-176669|Reactome:R-HSA-176604|Reactome:R-HSA-176588|RHEA:51064|Reactome:R-HSA-2022061 sulphotransferase activity Catalysis of the transfer of a sulfate group from 3'-phosphoadenosine 5'-phosphosulfate to the hydroxyl group of an acceptor, producing the sulfated derivative and 3'-phosphoadenosine 5'-phosphate. GO:0008145 phenylalkylamine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008145 Interacting selectively and non-covalently with phenylalkylamine or any of its derivatives. GO:0008144 drug binding biolink:MolecularActivity go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0008144 Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease. GO:0008143 poly(A) binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008143 poly-A binding|poly(rA) binding|poly(A) binding, within an RNA molecule|polyadenylate binding Interacting selectively and non-covalently with a sequence of adenylyl residues in an RNA molecule, such as the poly(A) tail, a sequence of adenylyl residues at the 3' end of eukaryotic mRNA. GO:0008142 oxysterol binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008142 Interacting selectively and non-covalently with oxysterol, an oxidized form of cholesterol. GO:0008152 metabolic process biolink:BiologicalProcess go-plus goslim_chembl|gocheck_do_not_manually_annotate|goslim_pir|goslim_plant|goslim_metagenomics http://purl.obolibrary.org/obo/GO_0008152 Wikipedia:Metabolism metabolism|metabolic process resulting in cell growth|metabolism resulting in cell growth|multicellular organism metabolic process|single-organism metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. GO:0008151 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008151 GO:0008150 biological_process biolink:BiologicalProcess go-plus goslim_chembl|goslim_yeast|goslim_candida|goslim_pir|goslim_plant|goslim_aspergillus|goslim_metagenomics|goslim_generic|goslim_pombe http://purl.obolibrary.org/obo/GO_0008150 Wikipedia:Biological_process biological process|single-organism process|physiological process|single organism process A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. GO:0033105 chlorosome envelope biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033105 chlorosome membrane The structure, composed of a monolayer of glycolipids with embedded proteins, that encloses the pigments and other contents of the chlorosome. GO:0033104 type VI protein secretion system complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033104 T6SS complex A complex of proteins that permits the transfer of proteins into the extracellular milieu or directly into host cells via the type VI secretion system. Proteins secreted by this complex do not require an N-terminal signal sequence. GO:0033103 protein secretion by the type VI secretion system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033103 protein secretion by the type VI protein secretion system|type VI protein secretion system|protein secretion by the T6SS The process in which proteins are transferred into the extracellular milieu or directly into host cells by the type VI secretion system. Proteins secreted by this system do not require an N-terminal signal sequence. GO:0033102 acidocalcisome membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033102 The lipid bilayer surrounding an acidocalcisome. GO:0033101 cellular bud membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033101 cellular bud plasma membrane The portion of the plasma membrane surrounding a cellular bud. GO:0033100 NuA3 histone acetyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033100 A Gcn5-independent multisubunit complex that catalyzes the acetylation of histone H3. The budding yeast complex includes Sas3p, Taf30p, and Yng1p. GO:0008159 obsolete positive transcription elongation factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008159 positive transcription elongation factor activity OBSOLETE. Any activity that increases the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule following transcription initiation. GO:0008158 hedgehog receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008158 patched activity Combining with a member of the hedgehog protein family and transmitting the signal across the membrane to initiate a change in cell activity. GO:0008157 protein phosphatase 1 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008157 Interacting selectively and non-covalently with the enzyme protein phosphatase 1. GO:0008156 negative regulation of DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008156 down regulation of DNA replication|downregulation of DNA replication|DNA replication inhibitor|down-regulation of DNA replication|inhibition of DNA replication Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication. GO:0008155 obsolete larval behavior (sensu Drosophila) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008155 larval behavior (sensu Drosophila) OBSOLETE. (Was not defined before being made obsolete). GO:0008154 actin polymerization or depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008154 Assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament. GO:0008153 para-aminobenzoic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008153 para-aminobenzoic acid anabolism|para-aminobenzoic acid synthesis|p-aminobenzoic acid biosynthetic process|vitamin Bx biosynthesis|p-aminobenzoic acid biosynthesis|vitamin Bx biosynthetic process|para-aminobenzoic acid formation|4-aminobenzoic acid biosynthetic process|4-aminobenzoic acid biosynthesis|PABA biosynthetic process|PABA biosynthesis|para-aminobenzoic acid biosynthesis The chemical reactions and pathways resulting in the formation of para-aminobenzoic acid, an intermediate in the synthesis of folic acid, a compound which some organisms, e.g. prokaryotes, eukaryotic microbes, and plants, can synthesize de novo. Others, notably mammals, cannot. In yeast, it is present as a factor in the B complex of vitamins. GO:0008163 obsolete DDT resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008163 DDT resistance OBSOLETE. (Was not defined before being made obsolete). GO:0008162 obsolete cyclodiene resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008162 cyclodiene resistance OBSOLETE. (Was not defined before being made obsolete). GO:0008161 obsolete carbamate resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008161 carbamate resistance OBSOLETE. (Was not defined before being made obsolete). GO:0008160 protein tyrosine phosphatase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008160 Increases the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a tyrosyl phenolic group of a protein. GO:0008129 obsolete actinidain activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008129 actinidin activity|actinidain activity|proteinase A2 of actinidia chinensis|actinidia anionic protease activity OBSOLETE. Catalysis of the hydrolysis of proteins with broad specificity for peptide bonds, with preference for a residue bearing a large hydrophobic side chain at the P2 position. Does not accept Val at P1'. GO:0008128 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008128 GO:0008127 quercetin 2,3-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008127 KEGG_REACTION:R02156|RHEA:15381|EC:1.13.11.24|MetaCyc:QUERCETIN-23-DIOXYGENASE-RXN|Reactome:R-HSA-8953398|UM-BBD_reactionID:r0891 flavonol 2,4-oxygenase activity|quercetin:oxygen 2,3-oxidoreductase (decyclizing)|quercetinase activity Catalysis of the reaction: H(+) + O(2) + quercetin = 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate + CO. GO:0008126 acetylesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008126 UM-BBD_reactionID:r0170|EC:3.1.1.6|RHEA:12957|MetaCyc:ACETYLESTERASE-RXN C-esterase (in animal tissues)|p-nitrophenyl acetate esterase|acetic ester hydrolase activity|chloroesterase|citrus acetylesterase|acetic-ester acetylhydrolase activity Catalysis of the reaction: an acetic ester + H2O = an alcohol + acetate. GO:0008125 obsolete pancreatic elastase I activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008125 pancreatopeptidase E activity|pancreatic elastase I activity|elaszym|serine elastase OBSOLETE. Catalysis of the hydrolysis of proteins, including elastin. Preferential cleavage: Ala-Xaa. CHEBI:2937 avenacoside A biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_2937 GO:0008124 4-alpha-hydroxytetrahydrobiopterin dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008124 MetaCyc:RXN-7908|Reactome:R-HSA-71146|RHEA:11920|KEGG_REACTION:R04734|EC:4.2.1.96 pterin-4-alpha-carbinolamine dehydratase activity|4a-hydroxytetrahydrobiopterin dehydratase activity|4alpha-hydroxy-tetrahydropterin dehydratase activity|4a-hydroxytetrahydrobiopterin hydro-lyase activity|4-alpha-hydroxy-tetrahydropterin dehydratase activity|pterin-4a-carbinolamine dehydratase activity|pterin-4alpha-carbinolamine dehydratase activity|(6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin hydro-lyase [(6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin-forming]|tetrahydrobiopterin dehydratase activity Catalysis of the reaction: (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H(2)O. GO:0008123 cholesterol 7-alpha-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008123 EC:1.14.14.23|Reactome:R-HSA-192051|MetaCyc:CHOLESTEROL-7-ALPHA-MONOOXYGENASE-RXN|RHEA:21812 cholesterol 7alpha-monooxygenase activity|cholesterol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating)|cholesterol 7alpha-hydroxylase activity|cytochrome P450 CYP7A1|cholesterol 7-alpha-hydroxylase activity Catalysis of the reaction: cholesterol + NADPH + H+ + O2 = 7-alpha-hydroxycholesterol + NADP+ + H2O. CHEBI:2938 avenacoside B biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_2938 GO:0008122 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008122 GO:0008121 ubiquinol-cytochrome-c reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008121 RHEA:11484|Reactome:R-HSA-164651|MetaCyc:1.10.2.2-RXN|EC:7.1.1.8 cytochrome b562|cytochrome c1|electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity|ubiquinone--cytochrome-c oxidoreductase activity|cytochrome|soluble cytochrome b562|ubiquinone-cytochrome c reductase activity|ubiquinone-cytochrome c oxidoreductase activity|cytochrome a3/copper complex|ubiquinol-cytochrome c-2 oxidoreductase activity|mitochondrial electron transport complex III|complex III (mitochondrial electron transport) activity|ubiquinol-cytochrome c2 reductase activity|cytochrome a|electron transporter, transferring electrons within cytochrome c oxidase complex activity|ubiquinol-cytochrome c oxidoreductase activity|ubiquinol-cytochrome c1 oxidoreductase activity|cytochrome b566|ubiquinol:ferricytochrome-c oxidoreductase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: CoQH2 + 2 ferricytochrome c = CoQ + 2 ferrocytochrome c + 2 H+. GO:0008120 ceramide glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008120 EC:2.4.1.80|RHEA:12088|Reactome:R-HSA-1638104|MetaCyc:CERAMIDE-GLUCOSYLTRANSFERASE-RXN UDP-glucose:N-acylsphingosine D-glucosyltransferase activity|ceramide:UDP-glucose glucosyltransferase activity|UDP-glucose-ceramide glucosyltransferase activity|UDPglucose:N-acylsphingosine D-glucosyltransferase activity|glucosylceramide synthase activity|UDP-glucose:ceramide glucosyltransferase activity|ceramide:UDPGlc glucosyltransferase activity|uridine diphosphoglucose-ceramide glucosyltransferase activity Catalysis of the reaction: UDP-glucose + N-acylsphingosine = UDP + D-glucosyl-N-acylsphingosine. GO:0008130 obsolete neutrophil collagenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008130 PMNL collagenase activity|matrix metalloproteinase 8 activity|neutrophil collagenase activity|MMP-8 OBSOLETE. Catalysis of the cleavage of interstitial collagens in the triple helical domain. Unlike EC:3.4.24.7, this enzyme cleaves type III collagen more slowly than type I. CHEBI:143624 D-galactofuranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_143624 CHEBI:73500 3-hydroxy-3-(4-hydroxyphenyl)propionyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73500 CHEBI:73504 (9Z)-octadecen-1-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73504 GO:0008139 nuclear localization sequence binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008139 NLS binding|nuclear localization signal binding|nuclear localisation sequence binding Interacting selectively and non-covalently with a nuclear localization sequence, a specific peptide sequence that acts as a signal to localize the protein within the nucleus. GO:0008138 protein tyrosine/serine/threonine phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008138 Reactome:R-HSA-5675376|Reactome:R-HSA-5675373|Reactome:R-HSA-9652816 dual-specificity protein phosphatase Catalysis of the reactions: protein serine + H2O = protein serine + phosphate; protein threonine phosphate + H2O = protein threonine + phosphate; and protein tyrosine phosphate + H2O = protein tyrosine + phosphate. GO:0008137 NADH dehydrogenase (ubiquinone) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008137 Reactome:R-HSA-163217|MetaCyc:RXN0-5330|MetaCyc:NADH-DEHYDROG-A-RXN|EC:7.1.1.2|RHEA:29091 type 1 dehydrogenase activity|dihydronicotinamide adenine dinucleotide-coenzyme Q reductase activity|NADH:ubiquinone oxidoreductase complex activity|NADH-coenzyme Q oxidoreductase activity|electron transfer complex I activity|DPNH-coenzyme Q reductase activity|NADH-CoQ oxidoreductase activity|DPNH-ubiquinone reductase activity|ubiquinone reductase activity|complex I (mitochondrial electron transport) activity|NADH coenzyme Q1 reductase activity|NADH-CoQ reductase activity|NADH:ubiquinone oxidoreductase activity|mitochondrial electron transport complex I activity|NADH-coenzyme Q reductase activity|complex 1 dehydrogenase activity|NADH-ubiquinone reductase activity|reduced nicotinamide adenine dinucleotide-coenzyme Q reductase activity|mitochondrial electron transport complex 1 activity|NADH-Q6 oxidoreductase activity|complex I (NADH:Q1 oxidoreductase) activity|NADH-ubiquinone-1 reductase activity|coenzyme Q reductase activity|NADH-ubiquinone oxidoreductase activity|complex I (electron transport chain) activity Catalysis of the reaction: NADH + ubiquinone + 5 H(+)(in) <=> NAD(+) + ubiquinol + 4 H(+)(out). GO:0008136 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008136 GO:0008135 translation factor activity, RNA binding biolink:MolecularActivity go-plus goslim_chembl|goslim_yeast|goslim_plant|goslim_generic http://purl.obolibrary.org/obo/GO_0008135 translation factor activity, nucleic acid binding Functions during translation by interacting selectively and non-covalently with RNA during polypeptide synthesis at the ribosome. GO:0008134 transcription factor binding biolink:MolecularActivity go-plus goslim_chembl|goslim_yeast|goslim_agr|goslim_drosophila|goslim_metagenomics|goslim_generic http://purl.obolibrary.org/obo/GO_0008134 TF binding Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription. GO:0008133 obsolete collagenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008133 collagenase activity OBSOLETE. Was not defined before being made obsolete. GO:0008132 obsolete pancreatic elastase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008132 pancreatic elastase activity OBSOLETE. Catalysis of the hydrolysis of proteins, including elastin. GO:0008131 primary amine oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008131 Reactome:R-HSA-379395|MetaCyc:RXN-9597|KEGG_REACTION:R01853|EC:1.4.3.21|Reactome:R-HSA-141186|Reactome:R-HSA-5696183|Reactome:R-HSA-374909|Reactome:R-HSA-379382|Reactome:R-HSA-5603108|Reactome:R-HSA-141200|Reactome:R-HSA-5696146|Reactome:R-HSA-141202 amine oxidase activity|amine oxidase (copper-containing) activity|primary-amine:oxygen oxidoreductase (deaminating) activity Catalysis of the reaction: a primary amine + H2O + O2 = an aldehyde + NH3 + hydrogen peroxide. GO:0008141 obsolete puparial glue (sensu Diptera) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008141 puparial glue (sensu Diptera) OBSOLETE. A glue which attaches the pupae to the substrate during metamorphosis, as in, but not restricted to, the true flies (Diptera, ncbi_taxonomy_id:7147). GO:0008140 cAMP response element binding protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008140 CBP|3',5' cAMP response element binding protein binding|CREB binding|cyclic AMP response element binding protein binding|adenosine 3',5'-cyclophosphate response element binding protein binding|3',5'-cAMP response element binding protein binding Interacting selectively and non-covalently with a cAMP response element binding protein (a CREB protein). GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008109 RHEA:17413|MetaCyc:2.4.1.150-RXN|EC:2.4.1.150 uridine diphosphoacetylglucosamine-acetyllactosaminide beta1->6-acetylglucosaminyltransferase|N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase activity|UDP-GlcNAc:Gal-R, beta-D-6-N-acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-1,4-N-acetyl-D-glucosaminide beta-1,6-N-acetyl-D-glucosaminyltransferase activity|galbeta1->4GlcNAc-R beta1->6 N-acetylglucosaminyltransferase activity|N-acetylglucosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,6-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R. GO:0008108 UDP-glucose:hexose-1-phosphate uridylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008108 EC:2.7.7.12|Reactome:R-HSA-5610038|Reactome:R-HSA-70361|KEGG_REACTION:R00955|MetaCyc:GALACTURIDYLYLTRANS-RXN|RHEA:13989 UDPglucose-hexose-1-phosphate uridylyltransferase activity|hexose 1-phosphate uridyltransferase activity|hexose-1-phosphate uridylyltransferase activity|galactose-1-phosphate uridylyltransferase activity|Gal-1-P uridylyltransferase activity|UDP-glucose-hexose-1-phosphate uridylyltransferase activity|UDP-glucose:alpha-D-galactose-1-phosphate uridylyltransferase activity|uridyl transferase activity|UDPglucose:alpha-D-galactose-1-phosphate uridylyltransferase activity|uridylyl removing enzyme activity|uridyltransferase activity Catalysis of the reaction: alpha-D-galactose 1-phosphate + UDP-D-glucose = alpha-D-glucose 1-phosphate + UDP-D-galactose. GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008107 MetaCyc:GALACTOSIDE-2-L-FUCOSYLTRANSFERASE-RXN|Reactome:R-HSA-9036987|Reactome:R-HSA-9603983|RHEA:50667|EC:2.4.1.69|Reactome:R-HSA-9603982 secretor-type beta-galactoside alpha1->2 fucosyltransferase activity|guanosine diphosphofucose-glycoprotein 2-alpha-fucosyltransferase activity|blood group H alpha-2-fucosyltransferase activity|blood-group substance H-dependent fucosyltransferase activity|guanosine diphosphofucose-galactoside 2-L-fucosyltransferase activity|guanosine diphosphofucose-glycoprotein 2-alpha-L-fucosyltransferase activity|guanosine diphosphofucose-galactosylacetylglucosaminylgalactosyl-glucosylceramide alpha-L-fucosyltransferase activity|guanosine diphosphofucose-galactosylacetylglucosaminylgalactosylglucosylceramide alpha-L-fucosyltransferase activity|H-gene-encoded beta-galactoside alpha-1->2 fucosyltransferase activity|H-gene-encoded beta-galactoside alpha1->2 fucosyltransferase activity|guanosine diphosphofucose-beta-D-galactosyl-alpha-2-L-fucosyltransferase activity|beta-galactoside alpha1->2 fucosyltransferase activity|beta-galactoside alpha-1->2 fucosyltransferase activity|alpha-2-fucosyltransferase activity|alpha-2-L-fucosyltransferase activity|secretor-type beta-galactoside alpha-1->2 fucosyltransferase activity|alpha(1,2)-L-fucosyltransferase activity|guanosine diphosphofucose-lactose fucosyltransferase activity|guanosine diphospho-L-fucose-lactose fucosyltransferase activity|alpha-(1->2)-L-fucosyltransferase activity|GDP-beta-L-fucose:beta-D-galactosyl-R 2-alpha-L-fucosyltransferase activity|galactoside 2-L-fucosyltransferase activity|GDP-L-fucose:lactose fucosyltransferase activity|GDP fucose-lactose fucosyltransferase activity Catalysis of the reaction: GDP-L-fucose + beta-D-galactosyl-R = GDP + alpha-L-fucosyl-(1,2)-beta-D-galactosyl-R. GO:0008106 alcohol dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008106 EC:1.1.1.2|MetaCyc:ALCOHOL-DEHYDROGENASE-NADP+-RXN|RHEA:15937 NADP-aldehyde reductase activity|aldehyde reductase (NADPH) activity|aldehyde reductase (NADPH2) activity|alcohol:NADP dehydrogenase activity Catalysis of the reaction: an alcohol + NADP+ = an aldehyde + NADPH + H+. CHEBI:48591 N-acylpiperidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48591 GO:0008105 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008105 GO:0008104 protein localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008104 asymmetric protein localisation|asymmetric protein localization|establishment and maintenance of protein localization|protein localisation|establishment and maintenance of asymmetric protein localization Any process in which a protein is transported to, or maintained in, a specific location. CHEBI:48590 hydroxypiperidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48590 GO:0008103 oocyte microtubule cytoskeleton polarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008103 Establishment and maintenance of a specific axis of polarity of the oocyte microtubule network. The axis is set so that the minus and plus ends of the microtubules of the mid stage oocyte are positioned along the anterior cortex and at the posterior pole, respectively. An example of this is found in Drosophila melanogaster. GO:0008102 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008102 CHEBI:48592 piperidinecarboxamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48592 CHEBI:48595 5'-S-methyl-5'-thioinosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48595 GO:0008101 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008101 GO:0008100 obsolete lipophorin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008100 lipophorin OBSOLETE. Any member of the major class of lipid-transporting proteins found in the hemolymph of insects. CHEBI:48597 arsenate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48597 CHEBI:48589 piperidones biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48589 GO:0008119 thiopurine S-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008119 MetaCyc:THIOPURINE-S-METHYLTRANSFERASE-RXN|Reactome:R-HSA-5603379|EC:2.1.1.67|Reactome:R-HSA-158609 TPMT|mercaptopurine methyltransferase activity|thiopurine methyltransferase activity|S-adenosyl-L-methionine:thiopurine S-methyltransferase activity|6-thiopurine transmethylase activity Catalysis of the reaction: S-adenosyl-L-methionine + a thiopurine = S-adenosyl-L-homocysteine + a thiopurine S-methylether. GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008118 EC:2.4.99.6|RHEA:52316|MetaCyc:2.4.99.6-RXN SiaT|CMP-N-acetylneuraminate:beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein alpha-2,3-N-acetylneuraminyltransferase activity|cytidine monophosphoacetylneuraminate-beta-galactosyl(1->4)acetylglucosaminide alpha2->3-sialyltransferase activity|alpha2->3 sialyltransferase activity Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein = CMP + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein. GO:0008117 sphinganine-1-phosphate aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008117 Reactome:R-HSA-428676|Reactome:R-HSA-428681|EC:4.1.2.27|MetaCyc:SPHINGANINE-1-PHOSPHATE-ALDOLASE-RXN|RHEA:18593 sphinganine-1-phosphate lyase activity|sphinganine-1-phosphate palmitaldehyde-lyase (phosphoethanolamine-forming)|sphingosine-1-phosphate lyase activity|dihydrosphingosine 1-phosphate aldolase activity|sphinganine-1-phosphate alkanal-lyase activity|sphingosine-1-phosphate aldolase activity|sphinganine-1-phosphate palmitaldehyde-lyase activity Catalysis of the reaction: sphinganine 1-phosphate = phosphoethanolamine + palmitaldehyde. GO:0008116 prostaglandin-I synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008116 EC:5.3.99.4|MetaCyc:PROSTAGLANDIN-I-SYNTHASE-RXN|KEGG_REACTION:R02267|Reactome:R-HSA-76496|RHEA:23580 PGI(2) synthase activity|PGI2 synthase activity|(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate 6-isomerase activity|prostacycline synthetase activity|PGI(2) synthetase activity|prostagladin I2 synthetase activity|prostacyclin synthase activity|cytochrome P450 CYP8A1|PGI2 synthetase activity Catalysis of the reaction: prostaglandin H(2) = prostaglandin I(2). GO:0008115 sarcosine oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008115 MetaCyc:SARCOX-RXN|KEGG_REACTION:R00610|RHEA:13313|EC:1.5.3.1 sarcosine:oxygen oxidoreductase (demethylating) Catalysis of the reaction: H(2)O + O(2) + sarcosine = formaldehyde + glycine + H(2)O(2). GO:0008114 phosphogluconate 2-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008114 EC:1.1.1.43|MetaCyc:1.1.1.43-RXN 6-phosphogluconate 2-dehydrogenase activity|2-keto-6-phosphogluconate reductase activity|phosphogluconate dehydrogenase activity|gluconate 6-phosphate dehydrogenase activity|6-phospho-D-gluconate:NAD(P)+ 2-oxidoreductase activity|6-phosphogluconate dehydrogenase (NAD)|6-phosphogluconic dehydrogenase activity Catalysis of the reaction: 6-phospho-D-gluconate + NADP+ = 6-phospho-2-dehydro-D-gluconate + NADPH. CHEBI:48582 ADP-D-ribose 1'',2''-cyclic phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48582 GO:0008113 peptide-methionine (S)-S-oxide reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008113 MetaCyc:RXN-8669|MetaCyc:RXN-8668|RHEA:14217|Reactome:R-HSA-5676940|EC:1.8.4.11|Reactome:R-HSA-1222363 methionine sulfoxide (protein) reductase activity|MsrA|methionine sulphoxide reductase A activity|methionine sulfoxide reductase A activity|protein-methionine-S-oxide reductase activity|peptide-methionine-(S)-S-oxide reductase activity|methionine sulfoxide reductase activity|methionine S-oxide reductase (S-form oxidizing) activity|methionine S-oxide reductase activity|peptide-L-methionine:thioredoxin-disulfide S-oxidoreductase [L-methionine (S)-S-oxide-forming] activity|peptide Met(O) reductase activity|peptide methionine sulfoxide reductase activity Catalysis of the reactions: peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin, and L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. Can act on oxidized methionine in peptide linkage with specificity for the S enantiomer. Thioredoxin disulfide is the oxidized form of thioredoxin. GO:0008112 nicotinamide N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008112 MetaCyc:NICOTINAMIDE-N-METHYLTRANSFERASE-RXN|KEGG_REACTION:R01269|RHEA:23884|Reactome:R-HSA-5359451|EC:2.1.1.1 nicotinamide methyltransferase activity|S-adenosyl-L-methionine:nicotinamide N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine(1+) + nicotinamide = 1-methylnicotinamide + S-adenosyl-L-homocysteine. CHEBI:48584 ADP-D-ribose 1''-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48584 GO:0008111 alpha-methylacyl-CoA racemase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008111 EC:5.1.99.4|Reactome:R-HSA-193763|RHEA:12657|MetaCyc:5.1.99.4-RXN|Reactome:R-HSA-389897|Reactome:R-HSA-192056|Reactome:R-HSA-193452|Reactome:R-HSA-193736 2-methylacyl-CoA 2-epimerase activity Catalysis of the reaction: (2S)-2-methylacyl-CoA = (2R)-2-methylacyl-CoA. GO:0008110 L-histidine:2-oxoglutarate aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008110 EC:2.6.1.38|RHEA:16565|KEGG_REACTION:R01161|MetaCyc:HISTTRANSAM-RXN histidine transaminase activity|histidine aminotransferase activity|histidine-2-oxoglutarate aminotransferase activity Catalysis of the reaction: 2-oxoglutarate + L-histidine = 3-(imidazol-5-yl)pyruvate + L-glutamate. CHEBI:48585 heteroarylpiperidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48585 GO:0072694 obsolete cell cycle arrest in response to caffeine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072694 OBSOLETE. The cell cycle regulatory process in which the cell cycle is halted during one of the normal phases (G1, S, G2, M) as a result of a caffeine stimulus. GO:0072693 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072693 GO:0072692 obsolete chromatin silencing at centromere central core biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072692 chromatin silencing at chromosome kinetochore domain|heterochromatic silencing at centromere central core|chromatin silencing at centromeric central core|centromere central core chromatin silencing OBSOLETE. Repression of transcription of DNA at the central core of a regional centromere by altering the structure of chromatin. GO:0072691 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072691 GO:0072690 single-celled organism vegetative growth phase biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0072690 stationary phase|vegetative growth of a single-celled organism A phase of population growth during which single celled organisms reproduce by budding, fission, or other asexual methods. CHEBI:2979 baicalein biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_2979 GO:0033086 negative regulation of extrathymic T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033086 negative regulation of extrathymic T cell development Any process that stops, prevents, or reduces the frequency, rate or extent of extrathymic T cell differentiation. GO:0033085 negative regulation of T cell differentiation in thymus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033085 negative regulation of thymocyte cell differentiation|negative regulation of thymocyte differentiation|negative regulation of T cell development in thymus|negative regulation of thymic T cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation in the thymus. GO:0033084 regulation of immature T cell proliferation in thymus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033084 regulation of thymocyte proliferation|regulation of thymic T cell proliferation|regulation of thymocyte cell proliferation Any process that modulates the frequency, rate or extent of immature T cell proliferation in the thymus. GO:0033083 regulation of immature T cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033083 Any process that modulates the frequency, rate or extent of immature T cell proliferation. GO:0033082 regulation of extrathymic T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033082 regulation of extrathymic T cell development Any process that modulates the frequency, rate or extent of extrathymic T cell differentiation. GO:0033081 regulation of T cell differentiation in thymus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033081 regulation of thymocyte cell differentiation|regulation of T cell development in thymus|regulation of thymocyte differentiation|regulation of thymic T cell differentiation Any process that modulates the frequency, rate or extent of T cell differentiation in the thymus. GO:0033080 immature T cell proliferation in thymus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033080 thymocyte cell proliferation|thymocyte proliferation|thymic T cell proliferation The expansion of an immature T cell population by cell division in the thymus. GO:0072699 protein localization to cortical microtubule cytoskeleton biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072699 protein localisation to cortical microtubule cytoskeleton A process in which a protein is transported to, or maintained at, a location within the cortical microtubule cytoskeleton. GO:0072698 protein localization to microtubule cytoskeleton biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072698 protein localisation to microtubule cytoskeleton A cellular protein localization process in which a protein is transported to, or maintained at, a location within the microtubule cytoskeleton. GO:0072697 protein localization to cell cortex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072697 protein localisation to cell cortex A process in which a protein is transported to, or maintained in, the cell cortex. GO:0033089 positive regulation of T cell differentiation in thymus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033089 positive regulation of T cell development in thymus|positive regulation of thymocyte differentiation|positive regulation of thymic T cell differentiation|positive regulation of thymocyte cell differentiation Any process that activates or increases the frequency, rate or extent of T cell differentiation in the thymus. GO:0033088 negative regulation of immature T cell proliferation in thymus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033088 negative regulation of thymocyte cell proliferation|negative regulation of thymocyte proliferation|negative regulation of thymic T cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation in the thymus. GO:0072696 positive regulation of DNA recombination at telomere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072696 upregulation of telomeric recombination at telomere|up regulation of telomeric recombination at telomere|activation of telomeric recombination at telomere|up-regulation of telomeric recombination at telomere|positive regulation of telomeric recombination Any process that activates or increases the frequency, rate or extent of DNA recombination within the telomere. GO:0033087 negative regulation of immature T cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033087 Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation. GO:0072695 regulation of DNA recombination at telomere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072695 regulation of telomeric recombination Any process that modulates the frequency, rate or extent of DNA recombination within the telomere. GO:0072683 T cell extravasation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072683 T lymphocyte extravasation|T-cell extravasation|T-lymphocyte extravasation The migration of a T cell from the blood vessels into the surrounding tissue. GO:0072682 eosinophil extravasation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072682 The migration of an eosinophil from the blood vessels into the surrounding tissue. GO:0072681 fibronectin-dependent thymocyte migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072681 fibronectin-dependent immature T-cell migration|fibronectin-dependent immature T-lymphocyte migration|fibronectin-dependent immature T cell migration|fibronectin-dependent thymic lymphocyte migration|fibronectin-dependent immature T lymphocyte migration The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development, dependent on fibronectin in the extracellular matrix. GO:0072680 extracellular matrix-dependent thymocyte migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072680 extracellular matrix-dependent immature T lymphocyte migration|extracellular matrix-dependent immature T-cell migration|extracellular matrix-dependent immature T-lymphocyte migration|extracellular matrix-dependent immature T cell migration|extracellular matrix-dependent thymic lymphocyte migration The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development, dependent on extracellular matrix components including fibronectin, collagen and laminin. GO:0033075 isoquinoline alkaloid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033075 isoquinoline alkaloid synthesis|isoquinoline alkaloid formation|ipecac alkaloid biosynthesis|isoquinoline alkaloid anabolism|isoquinoline alkaloid biosynthesis The chemical reactions and pathways resulting in the formation of isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin. GO:0033074 pinene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033074 pinene degradation|pinene breakdown|pinene catabolism The chemical reactions and pathways leading to the breakdown of the monoterpenoid pinene; alpha-pinene is (1S,5S)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene, and beta-pinene is (1S,5S)-6,6-dimethyl-2-methylenebicyclo[3.1.1]heptane. CHEBI:2981 baicalin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_2981 GO:0033073 pinene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033073 pinene metabolism The chemical reactions and pathways involving the monoterpenoid pinene; alpha-pinene is (1S,5S)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene, and beta-pinene is (1S,5S)-6,6-dimethyl-2-methylenebicyclo[3.1.1]heptane. GO:0033072 vancomycin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033072 vancomycin biosynthesis|vancomycin formation|vancomycin anabolism|vancomycin synthesis The chemical reactions and pathways leading to the formation of vancomycin, (3S,6R,7R,11R,23S,26S,30aS,36R,38aR)-44-[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-3-(carbamoylmethyl)-10,19-dichloro-2,3,4,5,6,7,23,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-(N-methyl-D-leucyl)-2,5,24,38,39-pentaoxo-1H,22H-23,36-(epiminomethano)-8,11:18,21-dietheno-13,16:31,35-di(metheno)[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine-26-carboxylic acid, a complex glycopeptide from Streptomyces orientalis that inhibits a specific step in the synthesis of the peptidoglycan layer in Gram-positive bacteria. GO:0033071 vancomycin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033071 vancomycin metabolism The chemical reactions and pathways involving vancomycin, (3S,6R,7R,11R,23S,26S,30aS,36R,38aR)-44-[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-3-(carbamoylmethyl)-10,19-dichloro-2,3,4,5,6,7,23,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-(N-methyl-D-leucyl)-2,5,24,38,39-pentaoxo-1H,22H-23,36-(epiminomethano)-8,11:18,21-dietheno-13,16:31,35-di(metheno)[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine-26-carboxylic acid, a complex glycopeptide from Streptomyces orientalis that inhibits a specific step in the synthesis of the peptidoglycan layer in Gram-positive bacteria. GO:0033070 ansamycin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033070 ansamycin anabolism|ansamycin synthesis|ansamycin formation|ansamycin biosynthesis The chemical reactions and pathways leading to the formation of ansamycins, any of a group of complex macrolactam compounds characterized by a cyclic structure in which an aliphatic ansa chain forms a bridge between two non-adjacent positions of a cyclic p-system; many exhibit antibacterial, antifungal or antitumor activity. GO:0072689 MCM complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072689 The aggregation, arrangement and bonding together of a set of components to form an MCM complex, a hexameric protein complex required for the initiation and regulation of DNA replication. GO:0072688 SHREC complex localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072688 establishment and maintenance of SHREC complex localization|SHREC complex localisation Any process in which a SHREC complex is transported to, or maintained in, a specific location. GO:0072687 meiotic spindle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0072687 A spindle that forms as part of meiosis. Several proteins, such as budding yeast Spo21p, fission yeast Spo2 and Spo13, and C. elegans mei-1, localize specifically to the meiotic spindle and are absent from the mitotic spindle. GO:0033079 immature T cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033079 The expansion of an immature T cell population by cell division. GO:0033078 extrathymic T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033078 extrathymic T cell development The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway independent of the thymus. GO:0072686 mitotic spindle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0072686 A spindle that forms as part of mitosis. Mitotic and meiotic spindles contain distinctive complements of proteins associated with microtubules. GO:0072685 Mre11 complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072685 Rad50-Rad32-Nbs1 complex assembly|MRN complex assembly|Rad50 complex assembly|MRX complex assembly|RMX complex assembly|RAD50-MRE11-NBN complex assembly The aggregation, arrangement and bonding together of a set of components to form an Mre11 complex, a trimeric protein complex that possesses endonuclease activity and is involved in meiotic recombination, DNA repair and checkpoint signaling. GO:0033077 T cell differentiation in thymus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033077 thymocyte cell differentiation|T cell development in thymus|thymocyte differentiation|thymic T cell differentiation The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway dependent upon transit through the thymus. GO:0072684 mitochondrial tRNA 3'-trailer cleavage, endonucleolytic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072684 mitochondrial tRNA 3'-end cleavage, endonucleolytic|mitochondrial endonucleolytic tRNA 3'-trailer cleavage|mitochondrial endonucleolytic tRNA 3'-end cleavage Endonucleolytic cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA in the mitochondrion. GO:0033076 isoquinoline alkaloid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033076 isoquinoline alkaloid metabolism|ipecac alkaloid metabolism The chemical reactions and pathways involving isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin. GO:0033064 XRCC2-RAD51D complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033064 DX2 complex A heterodimeric DNA recombinase mediator complex that contains the Rad51 paralogs RAD51D and XRCC2, or orthologs thereof; conserved from fission yeast to human but absent from budding yeast. GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033063 BCDX2 complex A DNA recombinase mediator complex that contains the Rad51 paralogs RAD51B, RAD51C, RAD51D, and XRCC2, or orthologs thereof. GO:0033062 Rhp55-Rhp57 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033062 Rad55-Rad57 complex A conserved heterodimeric DNA recombinase mediator complex that contains the RecA family proteins Rhp55p and Rph57 in Schizosaccharomyces, or orthologs thereof (e.g. Rad55p and Rad57p in Saccharomyces). GO:0033061 DNA recombinase mediator complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0033061 A protein complex containing accessory proteins which bind a recombinase (e.g. Rad51) and bind single-stranded DNA (ssDNA), and promote nucleation of the recombinase onto ssDNA through facilitating recombinase-RPA exchange. GO:0033060 ocellus pigmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033060 The deposition or aggregation of coloring matter in an ocellus, a minute simple eye found in many invertebrates. GO:0033069 ansamycin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033069 ansamycin metabolism The chemical reactions and pathways involving ansamycins, any of a group of complex macrolactam compounds characterized by a cyclic structure in which an aliphatic ansa chain forms a bridge between two non-adjacent positions of a cyclic p-system; many exhibit antibacterial, antifungal or antitumor activity. GO:0033068 macrolide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033068 macrolide anabolism|macrolide biosynthesis|macrolide synthesis|macrolide formation The chemical reactions and pathways leading to the formation of macrolides, any of a large group of polyketide compounds that contain a large lactone ring with few or no double bonds and no nitrogen atoms, linked glycosidically to one or more sugar groups. The macrolides include the carbomycins, the erythromycins, oleandomycin, oligomycins, and the spiramycins, and act as antibiotics, mainly against Gram-positive bacteria. GO:0033067 macrolide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033067 macrolide metabolism The chemical reactions and pathways involving macrolides, any of a large group of polyketide compounds that contain a large lactone ring with few or no double bonds and no nitrogen atoms, linked glycosidically to one or more sugar groups. The macrolides include the carbomycins, the erythromycins, oleandomycin, oligomycins, and the spiramycins, and act as antibiotics, mainly against Gram-positive bacteria. GO:0033066 Rad51B-Rad51C complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033066 BC complex A DNA recombinase mediator complex that contains the Rad51 paralogs RAD51B and RAD51C, or orthologs thereof. GO:0033065 Rad51C-XRCC3 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033065 CX3 complex A DNA recombinase mediator complex that contains the Rad51 paralogs RAD51C and XRCC3, or orthologs thereof. GO:0033053 D-glutamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033053 D-glutamine metabolism The chemical reactions and pathways involving D-glutamine, the D-enantiomer of the amino acid glutamine, i.e. (2R)-2,5-diamino-5-oxopentanoic acid. GO:0033052 cyanoamino acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033052 cyanoamino acid metabolism The chemical reactions and pathways involving cyanoamino acids, amino acid derivatives that contain a cyanide group. GO:0033051 aminophosphonate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033051 KEGG_PATHWAY:map00440 aminophosphonate metabolism The chemical reactions and pathways involving aminophosphonates, phosphonic acid derivatives that contain an amino group. GO:0033050 clavulanic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033050 Wikipedia:Clavulanic_acid clavulanic acid anabolism|clavulanic acid synthesis|clavulanic acid formation|clavulanic acid biosynthesis The chemical reactions and pathways resulting in the formation of clavulanic acid, (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid. GO:0033059 cellular pigmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033059 The deposition or aggregation of coloring matter in a cell. GO:0033058 directional locomotion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033058 Self-propelled movement of a cell or organism from one location to another along an axis. GO:0033057 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0033057 GO:0033056 D-ornithine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033056 D-ornithine metabolism The chemical reactions and pathways involving D-ornithine, the D-enantiomer of the amino acid ornithine, i.e. (2R)-2,5-diaminopentanoic acid. GO:0033055 D-arginine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033055 D-arginine metabolism The chemical reactions and pathways involving D-arginine, the D-enantiomer of the amino acid arginine, i.e. (2R)-2-amino-5-(carbamimidamido)pentanoic acid. GO:0033054 D-glutamate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033054 D-glutamate metabolism The chemical reactions and pathways involving D-glutamate, the D-enantiomer of the amino acid glutamate, i.e. (2R)-2-aminopentanedioic acid. GO:0008089 anterograde axonal transport biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0008089 anterograde axon cargo transport The directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons. GO:0008088 axo-dendritic transport biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0008088 Wikipedia:Axoplasmic_transport axon cargo transport|axoplasmic transport|axonal transport The directed movement of organelles or molecules along microtubules in neuron projections. GO:0008087 light-activated voltage-gated calcium channel complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0008087 light-activated voltage-dependent calcium channel complex|light-activated voltage-sensitive calcium channel complex|light-activated voltage gated calcium channel complex A protein complex that forms a transmembrane channel through which calcium ions may cross a cell membrane in response to changes in membrane potential generated in response to a light stimulus. GO:0008097 5S rRNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008097 Interacting selectively and non-covalently with 5S ribosomal RNA, the smallest RNA constituent of a ribosome. GO:0033042 umami taste receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033042 Combining with soluble umami compounds to initiate a change in cell activity. These receptors are responsible for the sense of umami taste, the savory taste of meats and other foods that are rich in glutamates. GO:0008096 juvenile hormone epoxide hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008096 EC:3.3.2.- Catalysis of the hydrolysis of the epoxide in a juvenile hormone to the corresponding diol. GO:0033041 sweet taste receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033041 Combining with soluble sweet compounds to initiate a change in cell activity. These receptors are responsible for the sense of sweet taste. GO:0033040 sour taste receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033040 Combining with soluble sour compounds to initiate a change in cell activity. These receptors are responsible for the sense of sour taste. GO:0008095 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008095 GO:0008094 DNA-dependent ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008094 DNA-dependent adenosinetriphosphatase activity|DNA dependent ATPase activity|adenosinetriphosphatase (DNA-dependent) Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of single- or double-stranded DNA, and it drives another reaction. GO:0008093 cytoskeletal anchor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008093 cytoskeletal adaptor activity The binding activity of a protein that brings together a cytoskeletal protein (either a microtubule or actin filament, spindle pole body, or protein directly bound to them) and one or more other molecules, permitting them to function in a coordinated way. GO:0008092 cytoskeletal protein binding biolink:MolecularActivity go-plus goslim_flybase_ribbon|goslim_chembl|goslim_mouse|goslim_agr|goslim_yeast|goslim_drosophila|goslim_generic http://purl.obolibrary.org/obo/GO_0008092 Interacting selectively and non-covalently with any protein component of any cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton). GO:0008091 spectrin biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0008091 Wikipedia:Spectrin|NIF_Subcellular:sao536287099 Membrane associated dimeric protein (240 and 220 kDa) of erythrocytes. Forms a complex with ankyrin, actin and probably other components of the membrane cytoskeleton, so that there is a mesh of proteins underlying the plasma membrane, potentially restricting the lateral mobility of integral proteins. GO:0008090 retrograde axonal transport biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0008090 retrograde axon cargo transport The directed movement of organelles or molecules along microtubules from the cell periphery toward the cell body in nerve cell axons. GO:0033049 clavulanic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033049 clavulanic acid metabolism The chemical reactions and pathways involving clavulanic acid, (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid. GO:0033048 negative regulation of mitotic sister chromatid segregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033048 Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation during mitosis. GO:0033047 regulation of mitotic sister chromatid segregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033047 Any process that modulates the frequency, rate or extent of sister chromatid segregation during mitosis. GO:0033046 negative regulation of sister chromatid segregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033046 Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation. GO:0033045 regulation of sister chromatid segregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033045 Any process that modulates the frequency, rate or extent of sister chromatid segregation. GO:0033044 regulation of chromosome organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033044 regulation of chromosome organisation|regulation of chromosome organization and biogenesis Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome. GO:0033043 regulation of organelle organization biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization and biogenesis|regulation of organelle organisation Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. GO:0008099 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008099 GO:0008098 5S rRNA primary transcript binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008098 Interacting selectively and non-covalently with the unprocessed 5S ribosomal RNA transcript. GO:0033031 positive regulation of neutrophil apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033031 activation of neutrophil apoptosis|up-regulation of neutrophil apoptosis|positive regulation of neutrophil apoptosis|up regulation of neutrophil apoptosis|upregulation of neutrophil apoptosis|stimulation of neutrophil apoptosis Any process that activates or increases the frequency, rate, or extent of neutrophil apoptotic process. GO:0033030 negative regulation of neutrophil apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033030 negative regulation of neutrophil apoptosis|down-regulation of neutrophil apoptosis|downregulation of neutrophil apoptosis|down regulation of neutrophil apoptosis|inhibition of neutrophil apoptosis Any process that stops, prevents, or reduces the frequency, rate, or extent of neutrophil apoptotic process. GO:0033039 salty taste receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033039 Combining with soluble salty compounds to initiate a change in cell activity. These receptors are responsible for the sense of salty taste. GO:0033038 bitter taste receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033038 Combining with soluble bitter compounds to initiate a change in cell activity. These receptors are responsible for the sense of bitter taste. GO:0033037 polysaccharide localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033037 polysaccharide localisation Any process in which a polysaccharide is transported to, or maintained in, a specific location. GO:0033036 macromolecule localization biolink:BiologicalProcess go-plus goslim_flybase_ribbon http://purl.obolibrary.org/obo/GO_0033036 macromolecule localisation Any process in which a macromolecule is transported to, or maintained in, a specific location. GO:0033035 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0033035 GO:0033034 positive regulation of myeloid cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033034 stimulation of myeloid cell apoptosis|up-regulation of myeloid cell apoptosis|activation of myeloid cell apoptosis|positive regulation of myeloid cell apoptosis|up regulation of myeloid cell apoptosis|upregulation of myeloid cell apoptosis Any process that activates or increases the frequency, rate, or extent of myeloid cell apoptotic process. GO:0033033 negative regulation of myeloid cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033033 negative regulation of myeloid cell apoptosis|down-regulation of myeloid cell apoptosis|downregulation of myeloid cell apoptosis|down regulation of myeloid cell apoptosis|inhibition of myeloid cell apoptosis Any process that stops, prevents, or reduces the frequency, rate, or extent of a myeloid cell apoptotic process. GO:0033032 regulation of myeloid cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033032 regulation of myeloid cell apoptosis Any process that modulates the frequency, rate, or extent of myeloid cell apoptotic process. GO:0033029 regulation of neutrophil apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033029 regulation of neutrophil apoptosis Any process that modulates the frequency, rate, or extent of neutrophil apoptotic process. GO:0008069 dorsal/ventral axis specification, ovarian follicular epithelium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008069 dorsal/ventral axis determination, follicular epithelium|dorsoventral axis specification, ovarian follicular epithelium|dorsal/ventral axis determination, ovarian follicular epithelium|dorsal-ventral axis specification, ovarian follicular epithelium Polarization of the ovarian follicle cells along the dorsal/ventral axis. An example of this process is found in Drosophila melanogaster. GO:0008068 extracellularly glutamate-gated chloride channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008068 extracellular-glutamate-gated chloride channel activity Enables the transmembrane transfer of a chloride ion by a channel that opens when glutamate is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane. GO:0008067 obsolete metabotropic glutamate, GABA-B-like receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008067 class C G protein coupled receptor|metabotropic glutamate, GABA-B-like receptor activity|class C orphan receptor activity|class C G-protein coupled receptor|class C GPCR OBSOLETE. A G protein-coupled receptor that is structurally/functionally related to the metabotropic glutamate receptor. GO:0008066 glutamate receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008066 Combining with glutamate and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0008065 establishment of blood-nerve barrier biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008065 establishment of blood/nerve barrier The establishment of the barrier between the perineurium of peripheral nerves and the vascular endothelium of endoneurial capillaries. The perineurium acts as a diffusion barrier, but ion permeability at the blood-nerve barrier is still higher than at the blood-brain barrier. GO:0008075 obsolete receptor guanylate cyclase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008075 receptor guanylate cyclase activity OBSOLETE. Catalysis of the reaction: GTP = 3',5'-cyclic GMP + diphosphate. GO:0033020 cyclopentanol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033020 cyclopentanol metabolism The chemical reactions and pathways involving cyclopentanol. GO:0008074 guanylate cyclase complex, soluble biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0008074 Complex that possesses guanylate cyclase activity and is not bound to a membrane. GO:0008073 ornithine decarboxylase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008073 The stopping, prevention or reduction of the activity of the enzyme ornithine decarboxylase. GO:0008072 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008072 GO:0008071 maternal determination of dorsal/ventral axis, ovarian follicular epithelium, soma encoded biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008071 maternal determination of dorsal/ventral axis, follicular epithelium, soma encoded|maternal determination of dorsoventral axis, ovarian follicular epithelium, soma encoded|maternal determination of dorsal-ventral axis, ovarian follicular epithelium, soma encoded Polarization of the ovarian follicle cells along the dorsal-ventral axis by a gene product encoded by somatic cells. An example of this process is found in Drosophila melanogaster. GO:0008070 maternal determination of dorsal/ventral axis, ovarian follicular epithelium, germ-line encoded biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008070 maternal determination of dorsal-ventral axis, ovarian follicular epithelium, germ-line encoded|maternal determination of dorsoventral axis, ovarian follicular epithelium, germ-line encoded Polarization of the ovarian follicle cells along the dorsal-ventral axis by a gene product encoded by cells of the germ line. GO:0033028 myeloid cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033028 apoptosis of myeloid cells|myeloid cell apoptosis Any apoptotic process in a myeloid cell, a cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage. GO:0033027 positive regulation of mast cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033027 up-regulation of mast cell apoptosis|upregulation of mast cell apoptosis|positive regulation of mast cell apoptosis|up regulation of mast cell apoptosis|activation of mast cell apoptosis|stimulation of mast cell apoptosis Any process that activates or increases the frequency, rate, or extent of mast cell apoptotic process. GO:0033026 negative regulation of mast cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033026 inhibition of mast cell apoptosis|down regulation of mast cell apoptosis|downregulation of mast cell apoptosis|negative regulation of mast cell apoptosis|down-regulation of mast cell apoptosis Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell apoptotic process. GO:0033025 regulation of mast cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033025 regulation of mast cell apoptosis Any process that modulates the frequency, rate, or extent of mast cell apoptotic process. GO:0033024 mast cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033024 mast cell apoptosis|apoptosis of mast cells Any apoptotic process in a mast cell, a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. GO:0033023 mast cell homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033023 The process of regulating the proliferation and elimination of mast cells such that the total number of mast cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. GO:0033022 cyclopentanol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033022 cyclopentanol breakdown|cyclopentanol degradation|cyclopentanol catabolism The chemical reactions and pathways resulting in the breakdown of cyclopentanol. GO:0033021 cyclopentanol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033021 cyclopentanol biosynthesis|cyclopentanol anabolism|cyclopentanol synthesis|cyclopentanol formation The chemical reactions and pathways resulting in the formation of cyclopentanol. GO:0033019 5-hydroxyvalerate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033019 Catalysis of the reaction: 5-hydroxyvalerate + NAD+ = 5-oxovalerate + NADH. GO:0033018 sarcoplasmic reticulum lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033018 The volume enclosed by the membranes of the sarcoplasmic reticulum. GO:0008079 translation termination factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008079 Functions in the termination of translation. GO:0008078 mesodermal cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008078 mesoderm cell migration The orderly movement of mesodermal cells from one site to another. GO:0008077 obsolete Hsp70/Hsp90 organizing protein activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008077 Hsp70/Hsp90 organizing protein activity|Hsp70/Hsp90 organising protein activity OBSOLETE. (Was not defined before being made obsolete). GO:0008076 voltage-gated potassium channel complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0008076 NIF_Subcellular:sao371494298 voltage-dependent potassium channel complex|voltage-sensitive potassium channel complex|voltage gated potassium channel complex A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential. GO:0008086 light-activated voltage-gated calcium channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008086 light-activated voltage-dependent calcium channel activity|light-activated voltage gated calcium channel activity Enables the transmembrane transfer of a calcium ion by a voltage-gated channel that is activated in response to light. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. GO:0008085 obsolete phototransduction, visible light, light adaptation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008085 phototransduction, visible light, light adaptation OBSOLETE. (Was not defined before being made obsolete). GO:0008084 imaginal disc growth factor receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008084 imaginal disc growth factor Interacting selectively and non-covalently with an imaginal disc growth factor receptor. GO:0008083 growth factor activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0008083 The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation. GO:0008081 phosphoric diester hydrolase activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0008081 EC:3.1.4.-|Reactome:R-HSA-5693578 phosphodiesterase Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group. GO:0008080 N-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008080 Reactome:R-HSA-6790987|Reactome:R-HSA-2468039|Reactome:R-HSA-9636560|Reactome:R-HSA-2473152 Catalysis of the transfer of an acetyl group to a nitrogen atom on the acceptor molecule. GO:0033017 sarcoplasmic reticulum membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033017 The lipid bilayer surrounding the sarcoplasmic reticulum. GO:0033016 rhoptry membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033016 The lipid bilayer surrounding a rhoptry. GO:0033015 tetrapyrrole catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033015 tetrapyrrole catabolism|tetrapyrrole degradation|tetrapyrrole breakdown The chemical reactions and pathways leading to the breakdown of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next. GO:0033014 tetrapyrrole biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033014 tetrapyrrole anabolism|tetrapyrrole synthesis|tetrapyrrole biosynthesis|tetrapyrrole formation The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next. GO:0033013 tetrapyrrole metabolic process biolink:BiologicalProcess go-plus goslim_pombe http://purl.obolibrary.org/obo/GO_0033013 tetrapyrrole metabolism The chemical reactions and pathways involving tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next. GO:0033012 porosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033012 Wikipedia:Porosome A permanent cup-shaped structure at the cell plasma membrane in secretory cells. Following a secretory stimulus, secretory vesicles transiently dock and fuse at the base of porosomes and release intravesicular contents dictated by the turgor pressure generated from the swelling of secretory vesicles. GO:0033011 perinuclear theca biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033011 A condensed cytoplasmic structure that covers the nucleus of mammalian spermatozoa except for a narrow zone around the insertion of the tail. It shows two distinct regions, a subacrosomal layer and, continuing caudally beyond the acrosomic system, the postacrosomal sheath. The perinuclear theca has been considered a cytoskeletal scaffold responsible for maintaining the overall architecture of the mature sperm head; however, recent studies indicate that the bulk of its constituent proteins are not traditional cytoskeletal proteins but rather a variety of cytosolic proteins. GO:0033010 paranodal junction biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033010 paranodal axoglial junction|paranodal septate junction|axoglial septate junction A highly specialized cell-cell junction found in vertebrates, which forms between a neuron and a glial cell, and has structural similarity to Drosophila septate junctions. It flanks the node of Ranvier in myelinated nerve and electrically isolates the myelinated from unmyelinated nerve segments and physically separates the voltage-gated sodium channels at the node from the cluster of potassium channels underneath the myelin sheath. GO:0047650 alkylglycerone kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047650 KEGG_REACTION:R03944|EC:2.7.1.84|RHEA:23088|MetaCyc:ALKYLGLYCERONE-KINASE-RXN ATP:O-alkylglycerone phosphotransferase activity|alkyldihydroxyacetone kinase (phosphorylating)|alkyldihydroxyacetone kinase activity Catalysis of the reaction: O-alkylglycerone + ATP = O-alkylglycerone phosphate + ADP + 2 H(+). CHEBI:24522 heptenedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24522 UBERON:0015791 digit connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015791 A portion of connective tissue that is part of a digit. UBERON:0015790 autopod skin biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015790 paw skin A zone of skin that is part of a autopod region. CHEBI:24521 heptenedioate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24521 CHEBI:24523 heptenone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24523 GO:0047658 alpha-amino-acid esterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047658 MetaCyc:ALPHA-AMINO-ACID-ESTERASE-RXN|EC:3.1.1.43|Reactome:R-HSA-6784959|RHEA:17241 alpha-amino acid ester hydrolase activity|alpha-amino-acid-ester aminoacylhydrolase activity|a-amino-acid esterase activity|alpha-amino-acid ester hydrolase activity Catalysis of the reaction: an alpha-amino acid ester + H2O = an alpha-amino acid + an alcohol. GO:0047657 alpha-1,3-glucan synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047657 MetaCyc:ALPHA-13-GLUCAN-SYNTHASE-RXN|RHEA:19749|EC:2.4.1.183 1,3-alpha-glucan synthase activity|UDPglucose:alpha-D-(1->3)-glucan 3-alpha-D-glucosyltransferase activity|a-1,3-glucan synthase activity|1,3-alpha-D-glucan synthase activity|UDP-glucose:alpha-D-(1->3)-glucan 3-alpha-D-glucosyltransferase activity|uridine diphosphoglucose-1,3-alpha-glucan glucosyltransferase activity Catalysis of the reaction: UDP-glucose + [alpha-D-glucosyl-(1,3)]n = UDP + [alpha-D-glucosyl-(1,3)]n+1. GO:0047656 alpha,alpha-trehalose phosphorylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047656 MetaCyc:ALPHAALPHA-TREHALOSE-PHOSPHORYLASE-RXN|EC:2.4.1.64|RHEA:23512 trehalose phosphorylase|alpha,alpha-trehalose:phosphate beta-D-glucosyltransferase activity|a,a-trehalose phosphorylase activity Catalysis of the reaction: alpha,alpha-trehalose + phosphate = D-glucose + beta-D-glucose 1-phosphate. GO:0047655 allyl-alcohol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047655 EC:1.1.1.54|RHEA:12168|KEGG_REACTION:R03572|MetaCyc:ALLYL-ALCOHOL-DEHYDROGENASE-RXN allyl-alcohol:NADP+ oxidoreductase activity Catalysis of the reaction: allyl alcohol + NADP(+) = acrolein + H(+) + NADPH. GO:0047654 alliin lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047654 MetaCyc:ALLIIN-LYASE-RXN|RHEA:20141|EC:4.4.1.4 cysteine sulfoxide lyase activity|L-cysteine sulfoxide lyase activity|alliinase activity|S-alkyl-L-cysteine S-oxide alkyl-sulfenate-lyase (2-aminoacrylate-forming)|alkylcysteine sulfoxide lyase activity|cysteine sulphoxide lyase activity|S-alkylcysteine sulfoxide lyase activity|alliin alkyl-sulfenate-lyase activity Catalysis of the reaction: an S-alkyl-L-cysteine S-oxide = an alkyl sulfenate + 2-aminoacrylate. UBERON:0015795 right lung lobar bronchus epitheium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015795 A epithelium that is part of a lobar bronchus of right lung. GO:0047653 allantoin racemase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047653 EC:5.1.99.3|RHEA:10804|KEGG_REACTION:R03925|MetaCyc:ALLANTOIN-RACEMASE-RXN Catalysis of the reaction: (S)-(+)-allantoin = (R)-(-)-allantoin. UBERON:0015794 left lung lobar bronchus epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015794 A epithelium that is part of a lobar bronchus of left lung. GO:0047652 allantoate deiminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047652 MetaCyc:ALLANTOATE-DEIMINASE-RXN|EC:3.5.3.9|RHEA:27485 allantoate amidinohydrolase (decarboxylating)|allantoate amidohydrolase activity Catalysis of the reaction: allantoate + H2O + H+ = CO2 + NH3 + ureidoglycine. UBERON:0015796 liver blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015796 hepatic blood vessel A blood vessel that is part of a liver. GO:0047651 alkylhalidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047651 KEGG_REACTION:R03523|RHEA:13765|EC:3.8.1.1|MetaCyc:ALKYLHALIDASE-RXN halogenase activity|alkyl-halide halidohydrolase activity|haloalkane halidohydrolase activity Catalysis of the reaction: bromochloromethane + H(2)O = bromide + chloride + formaldehyde + 2 H(+). UBERON:0001152 cystic duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001152 ductus cysticus the tubular structure that conducts gall bladder contents from the gall bladder to the common bile duct GO:0072619 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072619 GO:0072618 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072618 GO:0072617 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072617 GO:0072616 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072616 GO:0047659 alpha-santonin 1,2-reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047659 EC:1.3.1.47|MetaCyc:ALPHA-SANTONIN-12-REDUCTASE-RXN 1,2-dihydrosantonin:NAD(P)+ 1,2-oxidoreductase activity|a-santonin 1,2-reductase activity Catalysis of the reaction: 1,2-dihydrosantonin + NAD(P)+ = alpha-santonin + NAD(P)H + H+. GO:0072615 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072615 UBERON:0001158 descending colon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001158 colon descendens The portion of the colon between the left colic flexure and the sigmoid colon at the pelvic brim; the portion of the descending colon lying in the left iliac fossa is sometimes called the iliac colon. GO:0072614 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072614 GO:0072613 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072613 SO:0000315 TSS biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000315 transcription start site|transcription_start_site|INSDC_feature:misc_feature|INSDC_note:transcription_start_site The first base where RNA polymerase begins to synthesize the RNA transcript. UBERON:0001157 transverse colon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001157 colon transversum The proximal-distal subdivision of colon that runs transversely across the upper part of the abdomen, from the right to the left colic flexure. Continuous with the descending colon[BTO,modified]. GO:0072612 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072612 GO:0072611 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072611 UBERON:0001159 sigmoid colon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001159 sigmoid flexure|pelvic colon|colon sigmoideum|sigmoid colon The part of the large intestine that is closest to the rectum and anus. It forms a loop that averages about 40 cm. in length, and normally lies within the pelvis, but on account of its freedom of movement it is liable to be displaced into the abdominal cavity. CHEBI:24527 herbicide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24527 GO:0072610 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072610 UBERON:0001153 caecum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001153 intestinum caecum|cecum|blind intestine|intestinum crassum caecum|caecum|intestinum crassum cecum|blindgut|caeca|ceca A pouch in the digestive tract that connects the ileum with the ascending colon of the large intestine. It is separated from the ileum by the ileocecal valve, and is the beginning of the large intestine. It is also separated from the colon by the cecocolic junction. UBERON:0001156 ascending colon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001156 colon ascendens|spiral colon Section of colon which is distal to the cecum and proximal to the transversecolon.[FMA,modified] UBERON:0001155 colon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001155 posterior intestine|large bowel|hindgut Last portion of the large intestine before it becomes the rectum. GO:0047661 amino-acid racemase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047661 MetaCyc:AMINO-ACID-RACEMASE-RXN|EC:5.1.1.10|RHEA:18317 L-amino acid racemase activity Catalysis of the reaction: an L-amino acid = a D-amino acid. CHEBI:24533 heterodetic cyclic peptide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24533 GO:0047660 amidinoaspartase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047660 MetaCyc:AMIDINOASPARTASE-RXN|RHEA:14849|KEGG_REACTION:R00777|EC:3.5.3.14 N-amidino-L-aspartate amidinohydrolase activity|amidinoaspartic amidinohydrolase activity Catalysis of the reaction: N-amidino-L-aspartate + H(2)O = L-aspartate + urea. CHEBI:24532 organic heterocyclic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24532 CHEBI:24531 heterocyclic antibiotic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24531 CHEBI:24536 hexachlorocyclohexane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_24536 OBA:1000115 axon length biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_1000115 axon length trait|length of axon The length of a axon. GO:0047669 amylosucrase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047669 RHEA:24572|EC:2.4.1.4|MetaCyc:AMYLOSUCRASE-RXN sucrose-glucan glucosyltransferase activity|sucrose-1,4-alpha-glucan glucosyltransferase activity|sucrose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity Catalysis of the reaction: sucrose + 1,4-alpha-D-glucosyl(n) = D-fructose + 1,4-alpha-D-glucosyl(n+1). UBERON:0015788 olfactory apparatus chamber biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015788 An anatomical chamber that is part of the olfactory apparatus, consisting of cavity walls (nasal epithelium and mucosal layers) and the space bounded anteriorly by the nares and posteriorly by the choanae, when these structures are present. GO:0047668 amygdalin beta-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047668 EC:3.2.1.117|RHEA:14177|MetaCyc:AMYGDALIN-BETA-GLUCOSIDASE-RXN|KEGG_REACTION:R02985 amygdalin hydrolase activity|amygdalin b-glucosidase activity|amygdalin glucosidase activity|amygdalin beta-D-glucohydrolase activity|amygdalinase|(R)-amygdalin beta-glucosidase activity Catalysis of the reaction: (R)-amygdalin + H(2)O = (R)-prunasin + D-glucose. UBERON:0015787 upper respiratory conduit biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015787 respiratory conduit Any anatomical conduit which is part of the upper respiratory tract GO:0047667 AMP-thymidine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047667 EC:2.7.1.114|MetaCyc:AMP--THYMIDINE-KINASE-RXN|RHEA:14913 adenylic acid:deoxythymidine 5'-phosphotransferase activity|AMP:deoxythymidine 5'-phosphotransferase activity|AMP:thymidine 5'-phosphotransferase activity|thymidine phosphotransferase activity|AMP:deoxythymidine kinase activity|AMP:dThd kinase activity|adenylate-nucleoside phosphotransferase activity Catalysis of the reaction: AMP + thymidine = adenosine + thymidine 5'-phosphate. GO:0047666 ammonia kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047666 KEGG_REACTION:R00141|MetaCyc:AMMONIA-KINASE-RXN|EC:2.7.3.8|RHEA:11024 phosphoramidate-ADP-phosphotransferase activity|ATP:ammonia phosphotransferase activity|phosphoramidate-adenosine diphosphate phosphotransferase activity Catalysis of the reaction: ATP + NH(4)(+) = ADP + 3 H(+) + phosphoramidate. UBERON:0015789 cranial or facial muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015789 craniofacial muscle|cranio-facial muscle|cranial/facial muscle|cranial-facial muscle GO:0047665 aminolevulinate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047665 KEGG_REACTION:R02271|RHEA:12480|MetaCyc:AMINOLEVULINATE-AMINOTRANSFERASE-RXN|EC:2.6.1.43 L-alanine:4,5-dioxovaleric acid transaminase activity|alanine:4,5-dioxovalerate aminotransferase activity|5-aminolevulinate:pyruvate aminotransferase activity|L-alanine:dioxovalerate transaminase activity|5-aminolevulinic acid transaminase activity|alanine-dioxovalerate aminotransferase activity|aminolevulinic acid transaminase activity|aminolevulinate aminotransferase activity|4,5-dioxovaleric acid transaminase activity|4,5-dioxovalerate aminotransferase activity|dioxovalerate transaminase activity|L-alanine-4,5-dioxovalerate aminotransferase activity|gamma,delta-dioxovaleric acid transaminase activity|gamma,delta-dioxovalerate aminotransferase activity|4,5-dioxovaleric transaminase activity|alanine-gamma,delta-dioxovalerate aminotransferase activity|DOVA transaminase activity|4,5-dioxovaleric acid aminotransferase activity Catalysis of the reaction: 5-aminolevulinate + pyruvate = 4,5-dioxopentanoate + L-alanine. GO:0047664 aminoimidazolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047664 MetaCyc:R13-RXN|RHEA:22348|EC:3.5.4.8 4-aminoimidazole aminohydrolase activity|4-aminoimidazole hydrolase activity Catalysis of the reaction:4-aminoimidazole + H20 = imidazol-4-one + NH(3). UBERON:0015783 smooth muscle layer in fatty layer of subcutaneous tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015783 muscle layer in fatty layer of subcutaneous tissue|stratum musculosum panniculi adiposi telae subcutaneae A smooth muscle tissue that is part of a hypodermis. GO:0047663 aminoglycoside 6'-N-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047663 MetaCyc:AMINOGLYCOSIDE-N6-ACETYLTRANSFERASE-RXN|KEGG_REACTION:R01889|RHEA:16449|EC:2.3.1.82 6'-aminoglycoside-N-acetyltransferase activity|aminoglycoside N6'-acetyltransferase activity|AAC(6') activity|kanamycin 6'-N-acetyltransferase activity|aminoglycoside-6-N-acetyltransferase activity|aminoglycoside-6'-acetyltransferase activity|acetyl-CoA:kanamycin-B N6'-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + kanamycin B = N(6')-acetylkanamycin B + CoA + H(+). This is acetylation of the 6'-amino group of the 6-deoxy-6-aminoglucose ring. GO:0047662 aminobenzoate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047662 MetaCyc:AMINOBENZOATE-DECARBOXYLASE-RXN|EC:4.1.1.24|RHEA:24200 aminobenzoate carboxy-lyase activity|aminobenzoate carboxy-lyase (aniline-forming) Catalysis of the reaction: 4(or 2)-aminobenzoate = aniline + CO2. UBERON:0001141 right renal vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001141 A renal vein that drains the right kidney GO:0072609 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072609 UBERON:0001140 renal vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001140 vein of kidney|kidney vein|renal venous tree|venae renales Either of the pair of major vessels which arise from the renal hilus and return blood from the kidneys, suprarenal gland and the ureter to the inferior vena cava. GO:0072608 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072608 GO:0072607 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072607 GO:0072606 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072606 GO:0072605 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072605 GO:0072604 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072604 GO:0072603 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072603 SO:0000305 modified_DNA_base biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000305 modified base site|INSDC_feature:modified_base A modified nucleotide, i.e. a nucleotide other than A, T, C. G. UBERON:0001146 suprarenal vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001146 adrenal vein A vein that drains the adrenal gland. GO:0072602 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072602 GO:0072601 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072601 GO:0072600 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072600 UBERON:0001143 hepatic vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001143 liver vein|vein of liver|venae hepaticae|vena hepatica|hepatic veins Vein that carries blood away from the liver[ZFA]. UBERON:0001142 left renal vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001142 A renal vein that drains the left kidney UBERON:0001145 ovarian vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001145 female reproductive system gonad vein|vena ovarica sinistra|vein of female reproductive system gonad|vein of ovary|gonad of female reproductive system vein|vein of gonada of female reproductive system|vein of female reproductive system gonada|female reproductive system gonada vein|vena ovarica dextra|vein of gonad of female reproductive system|gonada of female reproductive system vein|ovary vein A vein that carries deoxygenated blood from its corresponding ovary to inferior vena cava or one of its tributaries. UBERON:0001144 testicular vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001144 venae spermaticae|testicle vein|vena testicularis dextra|vena tesicularis|spermatic vein|testicular venous tree|vein of testicle|vena testicularis sinistra|male gonadal vein A vein that carries deoxygenated blood from a single male gonad. It is the male equivalent of the ovarian vein, and is the venous counterpart of the testicular artery. It is a paired vein, with one supplying each testis. GO:0047672 anthranilate N-benzoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047672 RHEA:21600|KEGG_REACTION:R02453|EC:2.3.1.144|MetaCyc:ANTHRANILATE-N-BENZOYLTRANSFERASE-RXN benzoyl-CoA:anthranilate N-benzoyltransferase Catalysis of the reaction: anthranilate + benzoyl-CoA = N-benzoylanthranilate + CoA. CHEBI:24500 heparan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24500 GO:0047671 anthranilate adenylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047671 KEGG_REACTION:R00979|RHEA:22412|MetaCyc:ANTHRANILATE-ADENYLYLTRANSFERASE-RXN|EC:2.7.7.55 ATP:anthranilate N-adenylyltransferase activity|ATP:anthranilate adenylyltransferase activity|anthranilic acid adenylyltransferase activity Catalysis of the reaction: anthranilate + ATP = N-adenylylanthranilate + diphosphate + H(+). GO:0047670 anhydrotetracycline monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047670 RHEA:11976|KEGG_REACTION:R04060|EC:1.14.13.38|MetaCyc:ANHYDROTETRACYCLINE-MONOOXYGENASE-RXN anhydrotetracycline,NADPH:oxygen oxidoreductase (6-hydroxylating)|ATC oxygenase activity|anhydrotetracycline oxygenase activity Catalysis of the reaction: anhydrotetracycline + H(+) + NADPH + O(2) = 12-dehydrotetracycline + H(2)O + NADP(+). GO:0047679 arginine racemase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047679 EC:5.1.1.9|MetaCyc:ARGININE-RACEMASE-RXN|RHEA:18069 Catalysis of the reaction: L-arginine = D-arginine. GO:0047678 arginine 2-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047678 EC:1.13.12.1|KEGG_REACTION:R00559|RHEA:10548|MetaCyc:ARGININE-2-MONOOXYGENASE-RXN arginine monooxygenase activity|arginine oxygenase (decarboxylating) activity|arginine decarboxy-oxidase activity|L-arginine:oxygen 2-oxidoreductase (decarboxylating) Catalysis of the reaction: L-arginine + O(2) = 4-guanidinobutanamide + CO(2) + H(2)O. GO:0047677 arachidonate 8(R)-lipoxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047677 EC:1.13.11.40|RHEA:14985|KEGG_REACTION:R01594|MetaCyc:ARACHIDONATE-8-LIPOXYGENASE-RXN arachidonate:oxygen 8-oxidoreductase activity|arachidonate 8-lipoxygenase activity|8(R)-lipoxygenase activity|8-lipoxygenase activity Catalysis of the reaction: arachidonate + O(2) = (5Z,8R,9E,11Z,14Z)-8-hydroperoxyicosa-5,9,11,14-tetraenoate. GO:0047676 arachidonate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047676 MetaCyc:ARACHIDONATE--COA-LIGASE-RXN|EC:6.2.1.15|KEGG_REACTION:R01598|RHEA:19713 arachidonate:CoA ligase (AMP-forming)|arachidonoyl-CoA synthetase activity Catalysis of the reaction: arachidonate + ATP + CoA = AMP + arachidonoyl-CoA + diphosphate + H(+). GO:0047675 arabinonate dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047675 RHEA:21836|EC:4.2.1.5|KEGG_REACTION:R03032|MetaCyc:ARABINONATE-DEHYDRATASE-RXN D-arabinonate hydro-lyase (2-dehydro-3-deoxy-D-arabinonate-forming)|D-arabinonate hydro-lyase activity Catalysis of the reaction: D-arabinonate = 2-dehydro-3-deoxy-D-arabinonate + H(2)O. GO:0047674 apiose 1-reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047674 KEGG_REACTION:R03577|MetaCyc:APIOSE-1-REDUCTASE-RXN|RHEA:15301|EC:1.1.1.114 D-apiose reductase activity|D-apiitol:NAD+ 1-oxidoreductase activity|D-apiitol reductase activity Catalysis of the reaction: D-apiitol + NAD(+) = D-apiose + H(+) + NADH. GO:0047673 anthranilate N-malonyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047673 KEGG_REACTION:R00989|RHEA:17557|EC:2.3.1.113|MetaCyc:ANTHRANILATE-N-MALONYLTRANSFERASE-RXN malonyl-CoA:anthranilate N-malonyltransferase activity Catalysis of the reaction: anthranilate + malonyl-CoA = N-malonylanthranilate + CoA. UBERON:0001130 vertebral column biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001130 vertebral region|columna vertebralis|spine|dorsal spine|backbone|vertebral column skeleton|spinal column Subdivision of skeletal system that consists of all the vertebra and associated skeletal elements and joints in the body[modified from VSAO]. GO:0072639 interleukin-33 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0072639 NF-HEV production|IL-33 production|C9orf26 production|interleukin-33 secretion|IL1F11 production|interleukin-33 biosynthetic process|IL33 production The appearance of interleukin-33 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0072638 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072638 GO:0072637 interleukin-32 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0072637 TAIF production|IL-32 production|interleukin-32 secretion|NK4 production|interleukin-32 biosynthetic process|IL32 production The appearance of interleukin-32 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0072636 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072636 UBERON:0001136 mesothelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001136 Simple squamous epithelium of mesodermal origin which lines serous membranes. Examples: mesothelium of pleura, mesothelium of peritoneum[FMA]. Wikipedia: The mesothelium is a membrane that forms the lining of several body cavities: the pleura (thoracal cavity), peritoneum (abdominal cavity including the mesentery) and pericardium (heart sac). Mesothelial tissue also surrounds the male internal reproductive organs (the tunica vaginalis testis) and covers the internal reproductive organs of women (the tunica serosa uteri). UBERON:0001135 smooth muscle tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle|visceral muscle|involuntary muscle|textus muscularis nonstriatus|visceral muscle tissue|non-striated muscle|textus muscularis levis; textus muscularis nonstriatus Muscle tissue which is unstriated, composed primarily of smooth muscle fibers surrounded by a reticulum of collagen and elastic fibers. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length[GO]. GO:0072635 interleukin-31 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0072635 IL-31 production|interleukin-31 secretion The appearance of interleukin-31 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. UBERON:0001138 superior mesenteric vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001138 vena mesenterica superior|upper mesenteric vein In anatomy, the superior mesenteric vein (SMV) is a blood vessel that drains blood from the small intestine. At its termination behind the neck of the pancreas, the SMV combines with the splenic vein to form the hepatic portal vein. The SMV lies to the right of the similarly named artery, the superior mesenteric artery, which originates from the abdominal aorta. [WP,unvetted]. GO:0072634 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072634 GO:0072633 interleukin-30 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0072633 IL-30 production|interleukin-30 complex production|interleukin-30 secretion The appearance of interleukin-30 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. UBERON:0001137 dorsum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001137 back of body proper|dorsal part of organism|back A major subdivision of an organism that is the entire part of the organism dorsal to a horizontal plane and bounded on one side by the same transverse plane. In vertebrares this includes the vertebral column.. CHEBI:24505 heparins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24505 UBERON:0001132 parathyroid gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001132 epithelial body|parathyroid|parathyroid secreting cell The parathyroid gland is an endocrine gland for secretion of parathyroid hormone, usually found as a pair, embedded in the connective tissue capsule on the posterior surface of the thyroid gland. Parathyroid regulates calcium and phosphorous metabolism. GO:0072632 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072632 GO:0072631 interleukin-29 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0072631 interleukin-29 secretion|IL29 production|IL-29 production|interferon lambda 1 production The appearance of interleukin-29 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. UBERON:0001131 vertebral foramen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001131 vertebra neural canal|foramen vertebrale A foramen within a vertebral element through which the spinal cord runs. It is formed by the anterior segment, and the posterior part, the vertebral arch. GO:0072630 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072630 UBERON:0001134 skeletal muscle tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001134 skeletal muscle system|somatic muscle|skeletal muscle Muscle tissue that consists primarily of skeletal muscle fibers. UBERON:0001133 cardiac muscle tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001133 myocardium muscle tissue|muscle of heart muscle tissue|heart muscle muscle tissue|textus muscularis of cardiac muscle|cardiac musculature|heart myocardium muscle tissue|textus muscularis of myocardium|cardiac muscle|cardiac muscle textus muscularis|textus muscularis of heart muscle|muscle tissue of cardiac muscle|textus muscularis of heart myocardium|muscle tissue of muscle of heart|myocardium textus muscularis|muscle of heart textus muscularis|muscle tissue of myocardium|cardiac muscle muscle tissue|heart muscle textus muscularis|muscle tissue of heart muscle|heart myocardium textus muscularis|muscle tissue of heart myocardium|textus muscularis of muscle of heart Muscle tissue composed of cardiac muscle cells, forming the muscles of the heart[ZFA,modified]. SO:0000330 conserved_region biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000330 http://en.wikipedia.org/wiki/Conserved_region INSDC_note:conserved_region|INSDC_feature:misc_feature|conserved region Region of sequence similarity by descent from a common ancestor. GO:0047683 aryl-aldehyde dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047683 MetaCyc:ARYL-ALDEHYDE-DEHYDROGENASE-NADP+-RXN|EC:1.2.1.30|RHEA:19229 aryl-aldehyde:NADP+ oxidoreductase (ATP-forming)|aromatic acid reductase activity Catalysis of the reaction: an aromatic aldehyde + NADP+ + AMP + diphosphate + H2O = an aromatic acid + NADPH + ATP. GO:0047682 aryl-alcohol oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047682 MetaCyc:ARYL-ALCOHOL-OXIDASE-RXN|EC:1.1.3.7|RHEA:17541 arom. alcohol oxidase activity|aryl-alcohol:oxygen oxidoreductase activity|aryl alcohol oxidase activity|veratryl alcohol oxidase activity Catalysis of the reaction: an aromatic primary alcohol + O2 = an aromatic aldehyde + H2O2. GO:0047681 aryl-alcohol dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047681 MetaCyc:ARYL-ALCOHOL-DEHYDROGENASE-NADP+-RXN|EC:1.1.1.91|RHEA:17761 aryl alcohol dehydrogenase (nicotinamide adenine dinucleotide phosphate)|NADPH-linked benzaldehyde reductase activity|aryl-alcohol:NADP+ oxidoreductase activity Catalysis of the reaction: an aromatic alcohol + NADP+ = an aromatic aldehyde + NADPH. GO:0047680 aryl-acylamidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047680 MetaCyc:ARYL-ACYLAMIDASE-RXN|EC:3.5.1.13|KEGG_REACTION:R01862|RHEA:20297 AAA-2|AAA-1|pseudocholinesterase (associated with arylacylamidase)|aryl-acylamide amidohydrolase activity|brain acetylcholinesterase (is associated with AAA-2) Catalysis of the reaction: anilide + H(2)O = a carboxylate + aniline + H(+). UBERON:0001118 lobe of thyroid gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001118 thyroid lobe|lobuli glandulae thyroideae|lobus glandulae thyroideae|thyroid gland lobe|lobus (glandula thyroidea) A lobe of tissue that is part of a thyroid gland. UBERON:0001119 right lobe of thyroid gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001119 lobus dexter (glandula thyroidea)|thyroid gland right lobe|right thyroid lobe A lobe of thyroid gland that is in the right side of a thyroid gland. UBERON:0015766 epithelium of duct of salivary gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015766 salivary duct epithelium|salivary ductal epithelium|epithelium of salivary duct A epithelium that is part of a duct of salivary gland. GO:0047689 aspartate racemase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047689 KEGG_REACTION:R00491|MetaCyc:ASPARTATE-RACEMASE-RXN|EC:5.1.1.13|RHEA:14973 D-aspartate racemase activity Catalysis of the reaction: L-aspartate = D-aspartate. GO:0047688 aspartate 4-decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047688 MetaCyc:ASPARTATE-4-DECARBOXYLASE-RXN|EC:4.1.1.12|RHEA:12621 L-aspartate 4-carboxy-lyase (L-alanine-forming)|aspartate omega-decarboxylase activity|L-cysteine sulfinate acid desulfinase activity|aspartic beta-decarboxylase activity|L-aspartate 4-carboxy-lyase activity|desulfinase activity|cysteine sulfinic desulfinase activity|aspartic omega-decarboxylase activity|aminomalonic decarboxylase activity|aspartate beta-decarboxylase activity|L-aspartate beta-decarboxylase activity Catalysis of the reaction: L-aspartate = L-alanine + CO2. GO:0047687 obsolete ascorbate 2,3-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047687 MetaCyc:ASCORBATE-23-DIOXYGENASE-RXN|KEGG_REACTION:R00646|RHEA:21784 ascorbate:oxygen 2,3-oxidoreductase (bond-cleaving)|AAoxygenase activity|ascorbate 2,3-dioxygenase activity OBSOLETE. Catalysis of the reaction: L-ascorbate + H(2)O + O(2) = L-threonate + 2 H(+) + oxalate. GO:0047686 arylsulfate sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047686 MetaCyc:ARYLSULFATE-SULFOTRANSFERASE-RXN|EC:2.8.2.22|RHEA:51072 arylsulfate:phenol sulfotransferase activity|arylsulphate sulphotransferase activity|arylsulfate-phenol sulfotransferase activity|arylsulfotransferase|ASST Catalysis of the reaction: an aryl sulfate + a phenol = a phenol + an aryl sulfate. GO:0047685 amine sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047685 MetaCyc:ARYLAMINE-SULFOTRANSFERASE-RXN|RHEA:24136|EC:2.8.2.3 amine sulphotransferase activity|3'-phosphoadenylyl-sulfate:amine N-sulfotransferase activity|amine N-sulfotransferase activity|arylamine sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + an amine = adenosine 3',5'-bisphosphate + a sulfamate. PR:000024990 type II interferon biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000024990 interferon type II|interferon gamma|IFN type II A protein that binds to a specific cell surface receptor complex known as the IFN-gamma receptor (IFNGR), a complex of two IFNGR1 and two IFNGR2 chains. GO:0047684 arylamine glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047684 MetaCyc:ARYLAMINE-GLUCOSYLTRANSFERASE-RXN|EC:2.4.1.71 UDP-glucose:arylamine N-D-glucosyltransferase activity|UDP glucose-arylamine glucosyltransferase activity|uridine diphosphoglucose-arylamine glucosyltransferase activity|UDPglucose:arylamine N-D-glucosyltransferase activity Catalysis of the reaction: UDP-glucose + an arylamine = UDP + an N-D-glucosylarylamine. GO:0072629 interleukin-28B production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0072629 IL-28B production|IL28B production|interferon lambda 3 production|interleukin-28B secretion The appearance of interleukin-28B due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0072628 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072628 GO:0072627 interleukin-28A production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0072627 IL28A production|interferon lambda 2 production|interleukin-28A secretion|IL-28A production The appearance of interleukin-28A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0072626 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072626 UBERON:0001125 serratus ventralis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001125 serratus anterior|Boxer's muscle|serratus lateralis|musculus serratus anterior|serratus ventralis muscle|serratus anterior muscle The serratus ventralis is a muscle that originates on the surface of the upper eight or nine ribs at the side of the chest and inserts along the entire anterior length of the medial border of the scapula. [WP,unvetted]. GO:0072625 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072625 GO:0072624 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072624 GO:0072623 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072623 GO:0072622 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072622 GO:0072621 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072621 UBERON:0001120 left lobe of thyroid gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001120 thyroid gland left lobe|lobus sinister (glandula thyroidea)|left thyroid lobe A lobe of thyroid gland that is in the left side of a thyroid gland. GO:0072620 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072620 GO:0072650 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072650 GO:0047694 barbiturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047694 RHEA:18653|MetaCyc:BARBITURASE-RXN|EC:3.5.2.1 barbiturate amidohydrolase (3-oxo-3-ureidopropanoate-forming) Catalysis of the reaction: barbiturate + H2O = malonate + urea. GO:0047693 ATP diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047693 EC:3.6.1.8|RHEA:14245|MetaCyc:ATP-PYROPHOSPHATASE-RXN ATP pyrophosphatase activity|ATP diphosphohydrolase (diphosphate-forming)|adenosine triphosphate pyrophosphatase activity|ATP diphosphohydrolase Catalysis of the reaction: ATP + H2O = AMP + diphosphate. GO:0047692 ATP deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047692 EC:3.5.4.18|RHEA:13037|MetaCyc:ATP-DEAMINASE-RXN ATP aminohydrolase activity|adenosine triphosphate deaminase activity Catalysis of the reaction: ATP + H2O = ITP + NH3. GO:0047691 aspulvinone dimethylallyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047691 EC:2.5.1.35|KEGG_REACTION:R03799|RHEA:13809|MetaCyc:ASPULVINONE-DIMETHYLALLYLTRANSFERASE-RXN dimethylallyl-diphosphate:aspulvinone-E dimethylallyltransferase activity|dimethylallyl pyrophosphate:aspulvinone dimethylallyltransferase activity Catalysis of the reaction: aspulvinone E + 2 dimethylallyl diphosphate = aspulvinone H + 2 diphosphate. GO:0047690 aspartyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047690 KEGG_REACTION:R01485|EC:2.3.2.7|RHEA:11252|MetaCyc:ASPARTYLTRANSFERASE-RXN L-asparagine:hydroxylamine gamma-aspartyltransferase activity|beta-aspartyl transferase activity|aspartotransferase activity Catalysis of the reaction: L-asparagine + H(+) + hydroxylamine = beta-L-aspartylhydroxamate + NH(4)(+). GO:0047699 beta-diketone hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047699 EC:3.7.1.7|KEGG_REACTION:R03781|MetaCyc:BETA-DIKETONE-HYDROLASE-RXN|RHEA:11908 oxidized PVA hydrolase activity|nonane-4,6-dione acylhydrolase activity|b-diketone hydrolase activity Catalysis of the reaction: H(2)O + nonane-4,6-dione = butanoate + H(+) + pentan-2-one. GO:0047698 beta-alanyl-CoA ammonia-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047698 RHEA:12416|EC:4.3.1.6|MetaCyc:BETA-ALANYL-COA-AMMONIA-LYASE-RXN beta-alanyl-CoA ammonia-lyase (acryloyl-CoA-forming)|b-alanyl-CoA ammonia-lyase activity|beta-alanyl coenzyme A ammonia-lyase activity Catalysis of the reaction: beta-alanyl-CoA = acryloyl-CoA + NH3. GO:0047697 beta-alanopine dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047697 EC:1.5.1.26|RHEA:21684|MetaCyc:BETA-ALANOPINE-DEHYDROGENASE-RXN|KEGG_REACTION:R00906 b-alanopine dehydrogenase activity|N-(D-1-carboxyethyl)-beta-alanine:NAD+ oxidoreductase (beta-alanine-forming) Catalysis of the reaction: (R)-beta-alanopine + H(2)O + NAD(+) = beta-alanine + H(+) + NADH + pyruvate. GO:0047696 beta-adrenergic receptor kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047696 RHEA:19429|EC:2.7.11.15|Reactome:R-HSA-8866268|Reactome:R-HSA-8851797 ATP:beta-adrenergic-receptor phosphotransferase activity|beta-adrenoceptor kinase activity|beta-adrenergic receptor-specific kinase activity|betaARK1|adrenergic receptor kinase activity|beta-receptor kinase activity|beta-adrenoceptor kinase 1 activity|beta-adrenoceptor kinase 2 activity|[b-adrenergic-receptor] kinase activity|beta-ARK|beta-adrenergic-receptor kinase activity|beta-AR kinase activity|ADRBK1|BARK1|beta2ARK|GRK3|GRK2|beta-adrenergic-receptor kinase (phosphorylating) activity|beta-ARK 2|STK15|beta-ARK 1 Catalysis of the reaction: ATP + beta-adrenergic receptor = ADP + phospho-beta-adrenergic receptor. GO:0047695 benzoin aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047695 MetaCyc:BENZOIN-ALDOLASE-RXN|KEGG_REACTION:R00027|RHEA:21460|EC:4.1.2.38 2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase 2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase activity|2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase 2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase (benzaldehyde-forming)|2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase 2-hydroxy-1,2- activity|diphenylethanone benzaldehyde-lyase activity|benzaldehyde lyase activity Catalysis of the reaction: benzoin = 2 benzaldehyde. UBERON:0001194 splenic artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001194 lienal artery|arteria lienalis|arteria splenica An artery that supplies the spleen. UBERON:0001193 hepatic artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001193 arteria hepatica|arteria hepatica propria An artery that supplies the liver. UBERON:0001190 ovarian artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001190 arteria ovarica|ovarian arterial tree An artery that supplies an ovary. GO:0072659 protein localization to plasma membrane biolink:BiologicalProcess go-plus goslim_pombe http://purl.obolibrary.org/obo/GO_0072659 protein localization in plasma membrane|protein targeting to plasma membrane|protein localisation in plasma membrane|protein-plasma membrane targeting A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane. UBERON:0001191 common iliac artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001191 common iliac arterial tree|arteria iliaca communis The common iliac arteries are two large arteries, about 4cm long in adults but more than a centimetre in diameter, that originate from the aortic bifurcation. The arteries run inferolaterally, along the medial border of the psoas muscles to the pelvic brim, where they bifurcate into the external iliac artery and internal iliac artery. The common iliac artery, and all of its branches, exist as paired structures (that is to say, there is one on the left side and one on the right). The distribution of the common iliac artery is basically the pelvis and lower limb on the corresponding side. Both common iliac arteries are accompanied along their course by common iliac veins. [WP,unvetted]. GO:0072658 maintenance of protein location in membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072658 Any process in which a protein is maintained in a specific location in a membrane, and is prevented from moving elsewhere. GO:0072657 protein localization to membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072657 protein localisation in membrane|protein localization in membrane A process in which a protein is transported to, or maintained in, a specific location in a membrane. GO:0072656 maintenance of protein location in mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072656 Any process in which a protein is maintained in a specific location in a mitochondrion, and is prevented from moving elsewhere. GO:0072655 establishment of protein localization to mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072655 establishment of protein localisation to mitochondrion|establishment of protein localization in mitochondrion The directed movement of a protein to the mitochondrion or a part of the mitochondrion. OBA:1000142 vesicle size biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_1000142 vesicle size trait|size of vesicle The size of a vesicle. GO:0072654 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072654 GO:0072653 interferon-omega production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0072653 IFN-omega production|interferon-omega secretion|IFNW production The appearance of interferon-omega due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0072652 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072652 UBERON:0001199 mucosa of stomach biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001199 mucosa of organ of stomach|ventriculus mucosa|organ mucosa of ventriculus|gastric mucous membrane|ventriculus mucosa of organ|tunica mucosa (gaster)|gastric mucosa|stomach mucosa of organ|ventriculus mucous membrane|organ mucosa of stomach|Magenschleimhaut|stomach organ mucosa|stomach mucous membrane|ventriculus organ mucosa|tunica mucosa gastris|mucous membrane of ventriculus|mucosa of ventriculus|mucosa of organ of ventriculus|tunica mucosa gastricae|mucous membrane of stomach|stomach mucosa The mucosal layer that lines the stomach. GO:0072651 interferon-tau production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0072651 interferon-tau secretion|IFN-tau production|IFNT production|IFN-tau secretion The appearance of interferon-tau due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. UBERON:0001183 inferior mesenteric artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001183 arteria mesenterica inferior|inferior mesenteric arterial tree|IMA Mesenteric artery that supplies the large intestine from the left colic (or splenic) flexure to the upper part of the rectum, which includes the descending colon, the sigmoid colon, and part of the rectum. Proximally, its territory of distribution overlaps (forms a watershed) with the middle colic artery, and therefore the superior mesenteric artery. The SMA and IMA anastomose via the marginal artery (artery of Drummond). The territory of distribution of the IMA is more or less equivalent to the embryonic hindgut. [WP,unvetted]. UBERON:0001185 right renal artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001185 right renal arterial tree Renal artery that supplies the right kidney UBERON:0001184 renal artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001184 renal arterial tree|renal arteries|arteria renalis One of two laterally paired arteries that supplies the kidneys. These are large arteries that branch from the dorsal aorta in primitive vertebrates. GO:0072649 interferon-kappa production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0072649 interferon-kappa secretion|IFNK production|IFN-kappa production The appearance of interferon-kappa due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0072648 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072648 GO:0072647 interferon-epsilon production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0072647 interferon-epsilon secretion|IFN-epsilon production|IFNE production The appearance of interferon-epsilon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0072646 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072646 GO:0072645 interferon-delta production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0072645 interferon-delta secretion|IFN-delta production|IFND production The appearance of interferon-delta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0072644 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072644 GO:0072643 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072643 UBERON:0001187 testicular artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001187 internal spermatic|spermatic vessels|internal spermatic vessels|internal spermatic artery|internal spermatic arteries|spermatic artery|spermatic arteries|arteria testicularis|testicular arterial tree|testicular arteries One of a pair of arteries that is a branch of the abdominal aorta that supplies blood to a male gonad. GO:0072642 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072642 UBERON:0001186 left renal artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001186 left renal arterial tree Renal artery that supplies the left kidney GO:0072641 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072641 UBERON:0001189 left testicular artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001189 trunk of left testicular arterial tree|left spermatic artery A testicular artery that supplies a left testicle. UBERON:0001188 right testicular artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001188 right spermatic artery|trunk of right testicular arterial tree A testicular artery that supplies a right testicle. GO:0072640 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072640 GO:0072672 neutrophil extravasation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072672 The migration of a neutrophil from the blood vessels into the surrounding tissue. GO:0072671 mitochondria-associated ubiquitin-dependent protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072671 MAD|mitochondria-associated protein catabolic process|mitochondrion-associated protein catabolic process|mitochondria-associated protein degradation The chemical reactions and pathways resulting in the breakdown of proteins transported from mitochondria and targeted to cytoplasmic proteasomes for degradation as a response to oxidative stress conditions. GO:0072670 mitochondrial tRNA threonylcarbamoyladenosine modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072670 mitochondrial tRNA t6A modification The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in mitochondrial tRNAs that decode ANN codons (where N is any base). UBERON:2001156 posterior lateral line placode biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_2001156 UBERON:2001157 posterior lateral line primordium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_2001157 posterior lateral line primordia A migrating group of cells originating from the posterior lateral line placode. The primordium deposits seven to nine neuromasts and interneuromasts between them during its posterior migration to the tail. Gompel et al, 2001. UBERON:0001172 hepatic acinus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001172 portal acinus|liver acinus The functional unit of the liver, consisting of a mass of hepatocytes from adjacent liver lobules aligned around the hepatic arterioles and portal venules just as they anastomose into sinusoids. UBERON:0001171 portal lobule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001171 The triangular region on the periphery of the liver lobules that contain a bile duct and a terminal branch of the hepatic artery and portal vein, and may also include a lymphatic vessel. UBERON:0001174 common bile duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001174 ductus choledochus (biliaris)|ductus choledochus the part of the biliary tree formed by the union of the cystic duct and the common hepatic duct UBERON:0001173 biliary tree biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001173 biliary tract A complex network of conduits that begins with the canals of Hering (intralobar bile duct) and progressively merges into a system of interlobular, septal, and major ducts which then coalesce to form the extrahepatic bile ducts, which finally deliver bile to the intestine, and in some species to the gallbladder. UBERON:0001170 mesentery of small intestine biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001170 mesentery (proper)|mesentery proper|small intestine mesentery|small intestinal mesentery The peritoneum responsible for connecting the jejunum and ileum (parts of the small intestine) to the back wall of the abdomen. Between the two sheets of peritoneum are blood vessels, lymph vessels, and nerves. This allows these parts of the small intestine to move relatively freely within the abdominopelvic cavity. The brain, however, cannot map sensation accurately, so sensation is usually referred to the midline, an example of referred pain[WP]. GO:0072679 thymocyte migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072679 immature T cell migration|thymic lymphocyte migration|immature T lymphocyte migration|immature T-cell migration|immature T-lymphocyte migration The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development. UBERON:0001179 peritoneal cavity biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001179 cavitas peritonealis|saccus serosus peritonei Anatomical cavity bounded by visceral and parietal peritoneum GO:0072678 T cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072678 T-lymphocyte migration|T lymphocyte migration|T-cell migration The movement of a T cell within or between different tissues and organs of the body. GO:0072677 eosinophil migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072677 The movement of an eosinophil within or between different tissues and organs of the body. GO:0072676 lymphocyte migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072676 The movement of a lymphocyte within or between different tissues and organs of the body. UBERON:0001176 right hepatic duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001176 ductus hepaticus dexter The duct that drains bile from the right half of the liver and joins the left hepatic duct to form the common hepatic duct. GO:0072675 osteoclast fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072675 The plasma membrane fusion process that results in fusion of mononuclear osteoclasts to form a multinuclear osteoclast. UBERON:0001175 common hepatic duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001175 ductus hepaticus communis|hepatic duct Predominantly extrahepatic bile duct which is formed by the junction of the right and left hepatic ducts, which are predominantly intrahepatic, and, in turn, joins the cystic duct to form the common bile duct[GAID]. The common hepatic duct is the duct formed by the convergence of the right hepatic duct (which drains bile from the right functional lobe of the liver) and the left hepatic duct (which drains bile from the left functional lobe of the liver). The common hepatic duct then joins the cystic duct coming from the gallbladder to form the common bile duct[WP]. GO:0072674 multinuclear osteoclast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072674 multinuclear osteoclast morphogenesis|multinuclear osteoclast formation The process in which a relatively unspecialized monocyte acquires the specialized features of a multinuclear osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue. UBERON:0001178 visceral peritoneum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001178 visceral serous membrane of peritoneum The inner layer of peritoneum that is wrapped around organs located inside the intraperitoneal space. UBERON:0001177 left hepatic duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001177 ductus hepaticus sinister The duct that drains bile from the left half of the liver and joins the right hepatic duct to form the common hepatic duct. GO:0072673 lamellipodium morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072673 lamellipodium organization A process that is carried out at the cellular level and in which the structure of a lamellipodium is organized. GO:0072661 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072661 GO:0072660 maintenance of protein location in plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072660 Any process in which a protein is maintained in a specific location in the plasma membrane, and is prevented from moving elsewhere. SO:0000375 rRNA_5_8S biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000375 http://en.wikipedia.org/wiki/5.8S_ribosomal_RNA 5.8S rRNA|rRNA 5 8S|5.8S LSU rRNA|5.8S ribosomal RNA 5_8S ribosomal RNA (5. 8S rRNA) is a component of the large subunit of the eukaryotic ribosome. It is transcribed by RNA polymerase I as part of the 45S precursor that also contains 18S and 28S rRNA. Functionally, it is thought that 5.8S rRNA may be involved in ribosome translocation. It is also known to form covalent linkage to the p53 tumour suppressor protein. 5_8S rRNA is also found in archaea. SO:0000370 small_regulatory_ncRNA biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000370 small regulatory ncRNA A non-coding RNA less than 200 nucleotides long, usually with a specific secondary structure, that acts to regulate gene expression. These include short ncRNAs such as piRNA, miRNA and siRNAs (among others). UBERON:0001161 body of stomach biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001161 corpus gastricum|corpus gastricum (ventriculare)|stomach body|corpus ventriculare|gastric corpus|gastric body|corpus ventriculi The body of stomach is the part of the stomach that lies between the fundus above and the pyloric antrum below; its boundaries are poorly defined[GO]. GO:0033097 amyloplast membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033097 Either of the lipid bilayers that surround an amyloplast and form the amyloplast envelope. GO:0033096 amyloplast envelope biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033096 The double lipid bilayer enclosing the amyloplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space. GO:0033095 aleurone grain biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033095 aleurone body A membrane-bounded storage granule found in cells of the aleurone layer in plants; contains either a protein matrix, protein-carbohydrate bodies and/or globoids. Aleurone grains are formed by the vacuole, rough endoplasmic reticulum and dictyosomes. GO:0033094 butane-1,4-diamine:2-oxoglutarate aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033094 MetaCyc:2.6.1.82-RXN|RHEA:12268|EC:2.6.1.82 putrescine transaminase activity|putrescine:alpha-ketoglutarate aminotransferase activity|putrescine-alpha-ketoglutarate transaminase activity|putrescine aminotransferase activity|YgjG|putrescine:2-oxoglutarate aminotransferase activity|PAT activity Catalysis of the reaction: putrescine + 2-oxoglutarate = L-glutamate + 1-pyrroline + H2O. GO:0033093 Weibel-Palade body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033093 Wikipedia:Weibel-Palade_body A large, elongated, rod-shaped secretory granule characteristic of vascular endothelial cells that contain a number of structurally and functionally distinct proteins, of which the best characterized are von Willebrand factor (VWF) and P-selectin. Weibel-Palade bodies are formed from the trans-Golgi network in a process that depends on VWF, which is densely packed in a highly organized manner, and on coat proteins that remain associated with the granules. Upon cell stimulation, regulated exocytosis releases the contained proteins to the cell surface, where they act in the recruitment of platelets and leukocytes and in inflammatory and vasoactive responses. GO:0033092 positive regulation of immature T cell proliferation in thymus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033092 positive regulation of thymocyte cell proliferation|positive regulation of thymocyte proliferation|positive regulation of thymic T cell proliferation Any process that activates or increases the frequency, rate or extent of immature T cell proliferation in the thymus. GO:0033091 positive regulation of immature T cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033091 Any process that activates or increases the frequency, rate or extent of immature T cell proliferation. GO:0033090 positive regulation of extrathymic T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033090 positive regulation of extrathymic T cell development Any process that activates or increases the frequency, rate or extent of extrathymic T cell differentiation. GO:0072669 tRNA-splicing ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0072669 MetaCyc:ENTMULTI-CPLX tRNA splicing ligase complex A protein complex that catalyzes the ligation of cleaved pre-tRNAs by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. UBERON:0001169 wall of large intestine biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001169 large intestine anatomical wall|large intestine wall|large intestinal wall|anatomical wall of large intestine An anatomical wall that is part of a large intestine [Automatically generated definition]. GO:0072668 obsolete tubulin complex biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072668 tubulin complex biogenesis OBSOLETE. A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a tubulin complex. Includes the synthesis and folding of the constituent protein molecules, and those protein modifications that are involved in synthesis or assembly of the complex. A tubulin complex is a heterodimer of tubulins alpha and beta, from which microtubules are assembled. UBERON:0001168 wall of small intestine biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001168 small intestinal wall|anatomical wall of small bowel|wall of small bowel|anatomical wall of small intestine|small bowel anatomical wall|small intestine wall|small intestine anatomical wall|small bowel wall An anatomical wall that is part of a small intestine [Automatically generated definition]. GO:0072667 maintenance of protein location in vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072667 Any process in which a protein is maintained in a specific location in a vacuole, and is prevented from moving elsewhere. GO:0072666 establishment of protein localization to vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072666 establishment of protein localisation to vacuole The directed movement of a protein to a specific location in a vacuole. GO:0072665 protein localization to vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072665 protein localisation to vacuole A process in which a protein is transported to, or maintained at, a location in a vacuole. UBERON:0001165 pyloric antrum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001165 gastric antrum|antrum of Willis|stomach pyloric antrum|antrum pylori|antrum of stomach|antrum|stomach antrum|antrum pyloricum the area at the bottom of the stomach on the caudal side of the pyloric canal that contains gastrin-producing G cells, which stimulate acid production, and the luminal pH-sensitive population of somatostatin-producing D cells GO:0072664 maintenance of protein location in peroxisome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072664 Any process in which a protein is maintained in a specific location in a peroxisome, and is prevented from moving elsewhere. UBERON:0001167 wall of stomach biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001167 stomach anatomical wall|stomach wall|ventriculus wall|anatomical wall of ventriculus|wall of ventriculus|gastric wall|anatomical wall of stomach|ventriculus anatomical wall the layered structure that makes up the stomach, typiclly consists of a serous coat, a muscular coat, a mucous membrane, and other tissue layers in between GO:0033099 attachment organelle biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0033099 A membrane-bounded extension of the cell, originally characterized in Mycoplasma species, that contains an electron-dense core that is part of the cytoskeleton and is oriented lengthwise and ends distally in a bulbous knob (terminal button). Required for adherence to host cells and involved in gliding motility and cell division. GO:0072663 establishment of protein localization to peroxisome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072663 establishment of protein localisation to peroxisome The directed movement of a protein to a specific location in a peroxisome. UBERON:0001166 pylorus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001166 pars pylorica|stomach pyloric region|pyloric part of stomach|valvula pylori|pars pylorica gastricae|pyloric region the stomach tissue region surrounding and controlling the distal outlet of the stomach, which opens into the duodenum GO:0072662 protein localization to peroxisome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072662 protein localisation to peroxisome A process in which a protein is transported to, or maintained at, a location in a peroxisome. GO:0033098 amyloplast inner membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033098 The inner, i.e. lumen-facing, lipid bilayer of the amyloplast envelope; also faces the amyloplast stroma. CHEBI:48455 2-demethylmenaquinone-8 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48455 GO:0008209 androgen metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008209 androgen metabolism The chemical reactions and pathways involving androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics. GO:0008208 C21-steroid hormone catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008208 C21-steroid hormone degradation|C21-steroid hormone catabolism|C21-steroid hormone breakdown The chemical reactions and pathways resulting in the breakdown of C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones. GO:0008207 C21-steroid hormone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008207 C21-steroid hormone metabolism The chemical reactions and pathways involving C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones. GO:0008206 bile acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008206 bile acid metabolism The chemical reactions and pathways involving bile acids, any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine. CHEBI:73418 1-(1-hydroxyalkyl)-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73418 GO:0008205 ecdysone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008205 ecdysone metabolism The chemical reactions and pathways involving ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects. It is the inactive prohormone of the moulting hormone ecdysterone and may have intrinsic hormonal activity at other stages of insect development. GO:0008204 ergosterol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008204 ergosterol metabolism The chemical reactions and pathways involving ergosterol, (22E)-ergosta-5,7,22-trien-3-beta-ol, a sterol found in ergot, yeast and moulds. It is the most important of the D provitamins and is converted to vitamin D2 on irradiation with UV light. GO:0047812 D-amino-acid N-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047812 MetaCyc:D-AMINO-ACID-N-ACETYLTRANSFERASE-RXN|RHEA:20704|EC:2.3.1.36 acetyl-CoA:D-amino-acid N-acetyltransferase activity|D-amino acid acetyltransferase activity|D-amino acid-alpha-N-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + a D-amino acid = CoA + an N-acetyl-D-amino-acid. CHEBI:24480 heme o biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_24480 GO:0008203 cholesterol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008203 cholesterol metabolism The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues. GO:0047811 D-alanine gamma-glutamyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047811 MetaCyc:D-ALANINE-GAMMA-GLUTAMYLTRANSFERASE-RXN|EC:2.3.2.14|KEGG_REACTION:R01149|RHEA:23556 L-glutamine:D-alanine gamma-glutamyltransferase activity|D-alanine g-glutamyltransferase activity Catalysis of the reaction: D-alanine + L-glutamine = gamma-L-glutamyl-D-alanine + NH(4)(+). GO:0047810 D-alanine:2-oxoglutarate aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047810 MetaCyc:D-ALANINE-AMINOTRANSFERASE-RXN|RHEA:15869|EC:2.6.1.21 D-aspartate aminotransferase activity|D-amino acid aminotransferase activity|D-amino-acid transaminase activity|D-alanine aminotransferase activity|D-alanine-D-glutamate transaminase activity|D-aspartate transaminase activity|D-amino acid transaminase activity|D-alanine transaminase activity|D-aspartic aminotransferase activity Catalysis of the reaction: D-alanine + 2-oxoglutarate = pyruvate + D-glutamate. GO:0008202 steroid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008202 Wikipedia:Steroid_metabolism steroid metabolism The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. UBERON:0015834 duodenum lamina propria biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015834 lamina propria mucosae of duodenum|lamina propria of duodenum|duodenal lamina propria A lamina propria that is part of a duodenum. GO:0008201 heparin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008201 heparan sulfate binding Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues. UBERON:0015833 foregut epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015833 A epithelium that is part of a foregut. GO:0008200 ion channel inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008200 Stops, prevents, or reduces the activity of an ion channel. GO:0047819 D-glutamate(D-aspartate) oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047819 MetaCyc:D-GLUTAMATED-ASPARTATE-OXIDASE-RXN|EC:1.4.3.15 D-glutamic-aspartic oxidase activity|D-glutamate(D-aspartate):oxygen oxidoreductase (deaminating)|D-monoaminodicarboxylic acid oxidase activity Catalysis of the reaction: D-glutamate + H2O + O2 = 2-oxoglutarate + NH3 + H2O2, and D-aspartate + H2O + O2 = oxaloacetate + NH3 + H2O2. GO:0047818 D-fuconate dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047818 MetaCyc:D-FUCONATE-HYDRATASE-RXN|KEGG_REACTION:R03671|RHEA:12949|EC:4.2.1.67 D-fuconate hydratase activity|D-fuconate hydro-lyase (2-dehydro-3-deoxy-D-fuconate-forming)|D-fuconate hydro-lyase activity Catalysis of the reaction: D-fuconate = 2-dehydro-3-deoxy-D-fuconate + H(2)O. GO:0047817 D-arginase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047817 EC:3.5.3.10|RHEA:12901|KEGG_REACTION:R02458|MetaCyc:D-ARGINASE-RXN D-arginine amidinohydrolase activity Catalysis of the reaction: D-arginine + H(2)O = D-ornithine + urea. GO:0047816 D-arabinose 1-dehydrogenase (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047816 EC:1.1.1.116|MetaCyc:D-ARABINOSE-1-DEHYDROGENASE-RXN|RHEA:20457 NAD-pentose-dehydrogenase activity|arabinose(fucose)dehydrogenase activity|D-arabinose:NAD+ 1-oxidoreductase activity Catalysis of the reaction: D-arabinose + NAD+ = D-arabinono-1,4-lactone + NADH. GO:0047815 D-arabinonolactonase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047815 MetaCyc:D-ARABINONOLACTONASE-RXN|KEGG_REACTION:R02714|RHEA:23108|EC:3.1.1.30 D-arabinono-1,4-lactone lactonohydrolase activity Catalysis of the reaction: D-arabinono-1,4-lactone + H(2)O = D-arabinonate + H(+). GO:0047814 D-arabinokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047814 RHEA:24588|EC:2.7.1.54|KEGG_REACTION:R01573|MetaCyc:D-ARABINOKINASE-RXN D-arabinokinase (phosphorylating)|ATP:D-arabinose 5-phosphotransferase activity Catalysis of the reaction: D-arabinose + ATP = D-arabinose 5-phosphate + ADP. GO:0047813 D-arabinitol 4-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047813 RHEA:17921|MetaCyc:D-ARABINITOL-4-DEHYDROGENASE-RXN|EC:1.1.1.11 Catalysis of the reaction: D-arabinitol + NAD+ = D-xylulose + NADH. SO:0000275 snoRNA biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000275 http://en.wikipedia.org/wiki/SnoRNA INSDC_qualifier:snoRNA|INSDC_feature:ncRNA|small nucleolar RNA A snoRNA (small nucleolar RNA) is any one of a class of small RNAs that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins. They participate in the processing or modifications of many RNAs, mostly ribosomal RNAs (rRNAs) though snoRNAs are also known to target other classes of RNA, including spliceosomal RNAs, tRNAs, and mRNAs via a stretch of sequence that is complementary to a sequence in the targeted RNA. CHEBI:73423 1-(alk-1-enyl)-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73423 SO:0000274 snRNA biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000274 http://en.wikipedia.org/wiki/SnRNA small nuclear RNA|INSDC_feature:ncRNA|INSDC_qualifier:snRNA A small nuclear RNA molecule involved in pre-mRNA splicing and processing. CHEBI:24499 heparan sulfate proteoglycan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24499 SO:0000276 miRNA biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000276 http://en.wikipedia.org/wiki/StRNA|http://en.wikipedia.org/wiki/MiRNA INSDC_feature:ncRNA|micro RNA|INSDC_qualifier:miRNA|stRNA|microRNA|small temporal RNA Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene (or the product of other non coding RNA genes. Micro RNAs are produced from precursor molecules (SO:0000647) that can form local hairpin structures, which ordinarily are processed (usually via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors. GO:0008219 cell death biolink:BiologicalProcess go-plus goslim_chembl|goslim_mouse|goslim_agr|goslim_plant|goslim_drosophila|goslim_generic http://purl.obolibrary.org/obo/GO_0008219 necrosis|accidental cell death Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538). GO:0008218 bioluminescence biolink:BiologicalProcess go-plus goslim_chembl|goslim_metagenomics http://purl.obolibrary.org/obo/GO_0008218 Wikipedia:Bioluminescence The production of light by certain enzyme-catalyzed reactions in cells. GO:0008217 regulation of blood pressure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008217 Wikipedia:Blood_pressure#Regulation control of blood pressure|blood pressure regulation|blood pressure homeostasis Any process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure. GO:0008216 spermidine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008216 spermidine metabolism The chemical reactions and pathways involving spermidine, N-(3-aminopropyl)-1,4-diaminobutane. GO:0008215 spermine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008215 spermine metabolism The chemical reactions and pathways involving spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses, which is involved in nucleic acid packaging. Synthesis is regulated by ornithine decarboxylase which plays a key role in control of DNA replication. GO:0047823 D-glutamyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047823 RHEA:35623|MetaCyc:D-GLUTAMYLTRANSFERASE-RXN|EC:2.3.2.1 D-gamma-glutamyl transpeptidase activity|glutamine:D-glutamyl-peptide 5-glutamyltransferase activity|D-glutamyl transpeptidase activity Catalysis of the reaction: L(or D)-glutamine + D-glutamyl-peptide = NH3 + 5-glutamyl-D-glutamyl-peptide. GO:0008214 protein dealkylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008214 protein amino acid dealkylation The removal of an alkyl group from a protein amino acid. An alkyl group is any group derived from an alkane by removal of one hydrogen atom. GO:0047822 hypotaurine dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047822 MetaCyc:HYPOTAURINE-DEHYDROGENASE-RXN|KEGG_REACTION:R01681|EC:1.8.1.3|RHEA:17385|Reactome:R-HSA-1655453 hypotaurine:NAD+ oxidoreductase activity Catalysis of the reaction: H(2)O + hypotaurine + NAD(+) = H(+) + NADH + taurine. GO:0008213 protein alkylation biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0008213 protein amino acid alkylation The addition of an alkyl group to a protein amino acid. An alkyl group is any group derived from an alkane by removal of one hydrogen atom. GO:0047821 D-glutamate oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047821 RHEA:10028|KEGG_REACTION:R00279|EC:1.4.3.7|MetaCyc:D-GLUTAMATE-OXIDASE-RXN D-glutamic oxidase activity|D-glutamate:oxygen oxidoreductase (deaminating)|D-glutamic acid oxidase activity Catalysis of the reaction: D-glutamate + H2O + O2 = 2-oxoglutarate + NH3 + H2O2. GO:0047820 D-glutamate cyclase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047820 EC:4.2.1.48|MetaCyc:D-GLUTAMATE-CYCLASE-RXN|KEGG_REACTION:R01583|RHEA:22360 D-glutamate hydro-lyase (cyclizing; 5-oxo-D-proline-forming)|D-glutamate hydro-lyase (cyclizing) Catalysis of the reaction: D-glutamate = 5-oxo-D-proline + H(2)O. GO:0008212 mineralocorticoid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008212 mineralocorticoid metabolism The chemical reactions and pathways involving mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Mineralocorticoids act primarily on water and electrolyte balance. GO:0008211 glucocorticoid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008211 glucocorticoid metabolism|glucocorticosteroid metabolism|glucocorticosteroid metabolic process The chemical reactions and pathways involving glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects. GO:0008210 estrogen metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008210 oestrogen metabolism|oestrogen metabolic process|estrogen metabolism The chemical reactions and pathways involving estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants. CHEBI:24495 heparan alpha-D-glucosaminide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24495 GO:0047829 D-nopaline dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047829 EC:1.5.1.19|RHEA:19637|MetaCyc:D-NOPALINE-DEHYDROGENASE-RXN D-nopaline synthase activity|nopaline synthase activity|NOS activity|2-N-(D-1,3-dicarboxypropyl)-L-arginine:NADP+ oxidoreductase (L-arginine-forming)|nopaline dehydrogenase activity|N2-(D-1,3-dicarboxypropyl)-L-arginine:NADP+ oxidoreductase (L-arginine-forming) Catalysis of the reaction: N2-(D-1,3-dicarboxypropyl)-L-arginine + NADP+ + H2O = L-arginine + 2-oxoglutarate + NADPH. GO:0047828 D-lyxose ketol-isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047828 EC:5.3.1.15|KEGG_REACTION:R01898|RHEA:14201|MetaCyc:D-LYXOSE-KETOL-ISOMERASE-RXN D-lyxose aldose-ketose-isomerase activity|D-lyxose isomerase activity Catalysis of the reaction: D-lyxose = D-xylulose. GO:0047827 D-lysopine dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047827 MetaCyc:D-LYSOPINE-DEHYDROGENASE-RXN|EC:1.5.1.16|KEGG_REACTION:R00452|RHEA:17625 N2-(D-1-carboxyethyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)|D-lysopine synthase activity|D(+)-lysopine dehydrogenase activity|2-N-(D-1-carboxyethyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)|lysopine dehydrogenase activity Catalysis of the reaction: D-lysopine + H(2)O + NADP(+) = L-lysine + H(+) + NADPH + pyruvate. UBERON:0015814 outer ear epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015814 A epithelium that is part of a external ear. GO:0047826 D-lysine 5,6-aminomutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047826 KEGG_REACTION:R02852|MetaCyc:D-LYSINE-56-AMINOMUTASE-RXN|EC:5.4.3.4|RHEA:18241 adenosylcobalamin-dependent D-lysine 5,6-aminomutase activity|D-2,6-diaminohexanoate 5,6-aminomutase activity|D-alpha-lysine mutase activity Catalysis of the reaction: D-lysine = 2,5-diaminohexanoate. UBERON:0015813 middle ear epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015813 A epithelium that is part of a middle ear. GO:0047825 D-lactate-2-sulfatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047825 EC:3.1.6.17|KEGG_REACTION:R01448|RHEA:20337|MetaCyc:D-LACTATE-2-SULFATASE-RXN (S)-2-O-sulfolactate 2-sulfohydrolase activity|D-lactate-2-sulphatase activity Catalysis of the reaction: (R)-2-O-sulfolactate + H(2)O = (R)-lactate + H(+) + sulfate. GO:0047824 D-iditol 2-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047824 EC:1.1.1.15|RHEA:12725|MetaCyc:D-IDITOL-2-DEHYDROGENASE-RXN Catalysis of the reaction: D-iditol + NAD+ = D-sorbose + NADH. CHEBI:48433 angiotensin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48433 CHEBI:48436 thiophenecarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48436 CHEBI:24469 haloalkane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24469 GO:0047834 D-threo-aldose 1-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047834 RHEA:19645|EC:1.1.1.122|MetaCyc:D-THREO-ALDOSE-1-DEHYDROGENASE-RXN dehydrogenase, L-fucose|(2S,3R)-aldose dehydrogenase activity|L-fucose dehydrogenase activity|L-fucose (D-arabinose) dehydrogenase activity|D-threo-aldose:NAD+ 1-oxidoreductase activity Catalysis of the reaction: a D-threo-aldose + NAD+ = a D-threo-aldono-1,5-lactone + NADH. GO:0047833 D-sorbitol dehydrogenase (acceptor) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047833 EC:1.1.99.21|MetaCyc:D-SORBITOL-DEHYDROGENASE-RXN|RHEA:21320 D-sorbitol dehydrogenase activity|D-sorbitol:acceptor 1-oxidoreductase activity|D-sorbitol:(acceptor) 1-oxidoreductase activity Catalysis of the reaction: D-sorbitol + acceptor = L-sorbose + reduced acceptor. GO:0047832 D-pinitol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047832 MetaCyc:D-PINITOL-DEHYDROGENASE-RXN|EC:1.1.1.142|RHEA:20437|KEGG_REACTION:R03498 1D-3-O-methyl-chiro-inositol:NADP+ oxidoreductase activity|5D-5-O-methyl-chiro-inositol:NADP+ oxidoreductase activity Catalysis of the reaction: 5D-5-O-methyl-chiro-inositol + NADP(+) = 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + H(+) + NADPH. GO:0047831 D-ornithine 4,5-aminomutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047831 MetaCyc:ORNMUTST-RXN|EC:5.4.3.5|RHEA:14893|KEGG_REACTION:R02461 D-ornithine aminomutase activity|D-alpha-ornithine 5,4-aminomutase activity Catalysis of the reaction: D-ornithine = (2R,4S)-2,4-diaminopentanoate. GO:0047830 D-octopine dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047830 RHEA:16285|MetaCyc:D-OCTOPINE-DEHYDROGENASE-RXN|EC:1.5.1.11 2-N-(D-1-carboxyethyl)-L-arginine:NAD+ oxidoreductase (L-arginine-forming)|D-octopine synthase activity|octopine dehydrogenase activity|ODH activity|N2-(D-1-carboxyethyl)-L-arginine:NAD+ oxidoreductase (L-arginine-forming)|octopine:NAD oxidoreductase activity Catalysis of the reaction: N2-(D-1-carboxyethyl)-L-arginine + NAD+ + H2O = L-arginine + pyruvate + NADH. CHEBI:48430 4-methyl-2-oxopentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48430 CHEBI:24462 gulonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24462 CHEBI:24461 gulonate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24461 CHEBI:48432 angiotensin II biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48432 CHEBI:48431 formimidic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48431 UBERON:0015807 ear epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015807 A epithelium that is part of a ear. GO:0047839 dATP(dGTP)-DNA purinetransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047839 MetaCyc:DATPDGTP--DNA-PURINE-TRANSFERASE-RXN|EC:2.6.99.1 dATP(dGTP):depurinated-DNA purine transferase activity|dATP(dGTP)--DNA purine transferase activity Catalysis of the reaction: dATP + depurinated DNA = ribose triphosphate + DNA. UBERON:0015808 eye epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015808 A epithelium that is part of a camera-type eye. GO:0047838 D-xylose 1-dehydrogenase (NAD) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047838 RHEA:13861|EC:1.1.1.175|MetaCyc:D-XYLOSE-1-DEHYDROGENASE-RXN D-xylose:NAD+ 1-oxidoreductase activity|NAD-linked D-xylose dehydrogenase activity|(NAD)-linked D-xylose dehydrogenase activity|NAD-D-xylose dehydrogenase activity|D-xylose dehydrogenase activity|NAD-D-xylose Catalysis of the reaction: D-xylose + NAD+ = D-xylonolactone + NADH. GO:0047837 D-xylose 1-dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047837 RHEA:22000|EC:1.1.1.179|MetaCyc:D-XYLOSE-1-DEHYDROGENASE-NADP+-RXN|KEGG_REACTION:R01430 D-xylose:NADP+ 1-oxidoreductase activity|D-xylose-NADP dehydrogenase activity|D-xylose:NADP+ oxidoreductase activity|D-xylose (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity Catalysis of the reaction: D-xylose + NADP(+) = D-xylono-1,5-lactone + H(+) + NADPH. GO:0047836 D-tryptophan N-malonyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047836 RHEA:23320|KEGG_REACTION:R02482|EC:2.3.1.112|MetaCyc:D-TRYPTOPHAN-N-MALONYLTRANSFERASE-RXN malonyl-CoA:D-tryptophan N-malonyltransferase activity Catalysis of the reaction: D-tryptophan + malonyl-CoA = N(2)-malonyl-D-tryptophan + CoA + H(+). GO:0047835 D-tryptophan N-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047835 KEGG_REACTION:R02481|RHEA:10060|MetaCyc:D-TRYPTOPHAN-N-ACETYLTRANSFERASE-RXN|EC:2.3.1.34 D-tryptophan acetyltransferase activity|acetyl-CoA-D-tryptophan-alpha-N-acetyltransferase activity|acetyl-CoA:D-tryptophan N-acetyltransferase activity Catalysis of the reaction: D-tryptophan + acetyl-CoA = N-acetyl-D-tryptophan + CoA + H(+). CHEBI:48423 3-hydroxy-L-aspartic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48423 SO:0000296 origin_of_replication biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000296 http://en.wikipedia.org/wiki/Origin_of_replication ori|INSDC_feature:rep_origin|origin of replication A region of nucleic acid from which replication initiates; includes sequences that are recognized by replication proteins, the site from which the first separation of complementary strands occurs, and specific replication start sites. CHEBI:48422 angiogenesis inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48422 CHEBI:48427 N-formimidoyl-L-aspartic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48427 CHEBI:48429 N-formyl-L-aspartic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48429 CHEBI:24479 heme a biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24479 GO:0047845 deoxylimonate A-ring-lactonase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047845 EC:3.1.1.46|KEGG_REACTION:R03803|RHEA:14997|MetaCyc:DEOXYLIMONATE-A-RING-LACTONASE-RXN deoxylimonate A-ring-lactonohydrolase activity Catalysis of the reaction: deoxylimonoate + H(2)O = deoxylimononate D-ring-lactone + H(+). CHEBI:24470 haloamino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24470 GO:0047844 deoxycytidine deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047844 EC:3.5.4.14|RHEA:13433|MetaCyc:CYTIDEAM-RXN deoxycytidine aminohydrolase activity Catalysis of the reaction: deoxycytidine + H2O = deoxyuridine + NH3. GO:0047843 dehydrogluconate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047843 RHEA:12368|MetaCyc:DEHYDROGLUCONATE-DEHYDROGENASE-RXN|KEGG_REACTION:R07153|EC:1.1.99.4 2-keto-D-gluconate dehydrogenase activity|alpha-ketogluconate dehydrogenase activity|ketogluconate dehydrogenase activity|2-oxogluconate dehydrogenase activity|2-dehydro-D-gluconate:acceptor 2-oxidoreductase activity Catalysis of the reaction: 2-dehydro-D-gluconate + A = 2,5-didehydro-D-gluconate + AH(2). GO:0047842 dehydro-L-gulonate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047842 EC:4.1.1.34|RHEA:11084|Reactome:R-HSA-5662473|MetaCyc:DEHYDRO-L-GULONATE-DECARBOXYLASE-RXN|KEGG_REACTION:R01905 keto-L-gulonate decarboxylase activity|3-keto-L-gulonate decarboxylase activity|3-dehydro-L-gulonate carboxy-lyase (L-xylulose-forming)|3-dehydro-L-gulonate carboxy-lyase activity Catalysis of the reaction: 3-dehydro-L-gulonate + H(+) = L-xylulose + CO(2). GO:0047841 dehydrogluconokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047841 KEGG_REACTION:R02658|RHEA:10788|EC:2.7.1.13|MetaCyc:DEHYDOGLUCONOKINASE-RXN ketogluconokinase (phosphorylating)|dehydogluconokinase activity|ATP:2-dehydro-D-gluconate 6-phosphotransferase activity|ketogluconokinase activity|2-ketogluconokinase activity|2-ketogluconate kinase activity Catalysis of the reaction: 2-dehydro-D-gluconate + ATP = 6-phospho-2-dehydro-D-gluconate + ADP + 2 H(+). GO:0047840 dCTP diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047840 RHEA:22636|EC:3.6.1.12|MetaCyc:DCTP-PYROPHOSPHATASE-RXN|Reactome:R-HSA-6786257 dCTP pyrophosphatase activity|deoxycytidine triphosphatase activity|deoxy-CTPase activity|deoxycytidine-triphosphatase activity|dCTP nucleotidohydrolase activity|dCTPase activity Catalysis of the reaction: dCTP + H2O = dCMP + diphosphate. CHEBI:24473 halogen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24473 CHEBI:24472 halohydrocarbon biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24472 CHEBI:24471 halogen molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24471 CHEBI:48420 biphenylyltetrazole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48420 GO:0047849 dextransucrase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047849 MetaCyc:DEXTRANSUCRASE-RXN|EC:2.4.1.5 SGE|CEP|sucrose:1,6-alpha-D-glucan 6-alpha-D-glucosyltransferase activity|sucrose 6-glucosyltransferase activity|sucrose-1,6-alpha-glucan glucosyltransferase activity Catalysis of the reaction: sucrose + 1,6-alpha-D-glucosyl(n) = D-fructose + 1,6-alpha-D-glucosyl(n+1). GO:0047848 dephospho-[reductase kinase] kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047848 EC:2.7.11.3|MetaCyc:DEPHOSPHO-REDUCTASE-KINASE-KINASE-RXN hydroxymethylglutaryl coenzyme A reductase kinase kinase activity|AMP-activated kinase activity|reductase kinase kinase activity|hydroxymethylglutaryl coenzyme A reductase kinase kinase (phosphorylating) activity|STK30|reductase kinase activity|dephospho-reductase kinase kinase activity|AMP-activated protein kinase kinase activity|ATP:dephospho-{hydroxymethylglutaryl-CoA reductase (NADPH)kinase} phosphotransferase activity Catalysis of the reaction: ATP + dephospho-[[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase] = ADP + [[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase]. GO:0047847 deoxyuridine phosphorylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047847 RHEA:22824|EC:2.4.2.23|MetaCyc:DEOXYURIDINE-PHOSPHORYLASE-RXN deoxyuridine:phosphate deoxy-alpha-D-ribosyltransferase activity|2'-deoxyuridine:phosphate 2-deoxy-alpha-D-ribosyltransferase activity|deoxyuridine:phosphate deoxy-D-ribosyltransferase activity Catalysis of the reaction: deoxyuridine + phosphate = uracil + deoxy-D-ribose 1-phosphate. GO:0047846 deoxynucleotide 3'-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047846 EC:3.1.3.34|MetaCyc:DEOXYNUCLEOTIDE-3-PHOSPHATASE-RXN|RHEA:10092 3'-deoxynucleotidase activity|deoxyribonucleotide 3'-phosphohydrolase activity|3'-deoxyribonucleotidase activity Catalysis of the reaction: a deoxynucleoside 3'-phosphate + H2O = a deoxynucleoside + phosphate. UBERON:0015870 lymph node of head biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015870 A lymph node that is part of a head. CHEBI:24442 guanidinoethyl methyl phosphates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24442 UBERON:0001229 renal corpuscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001229 kidney corpuscle|corpusculum renis|cortical renal corpuscle|Malphigian corpuscle|Malpighian corpuscle|corpusculum renale the structure containing the glomerular capsule and the glomerulus that serves as the initial blood-filtering component of a nephron GO:0047856 dihydrocoumarin hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047856 MetaCyc:DIHYDROCOUMARIN-LIPASE-RXN|EC:3.1.1.35|KEGG_REACTION:R03692|RHEA:10360 dihydrocoumarin lactonohydrolase activity|dihydrocoumarin lipase activity Catalysis of the reaction: 3,4-dihydrocoumarin + H(2)O = 3-(2-hydroxyphenyl)propanoate + H(+). GO:0047855 dihydrobunolol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047855 MetaCyc:DIHYDROBUNOLOL-DEHYDROGENASE-RXN|EC:1.1.1.160|RHEA:15925|KEGG_REACTION:R04623 (+-)-5-[(tert-butylamino)-2'-hydroxypropoxy]-1,2,3,4-tetrahydro-1-naphthol:NADP+ oxidoreductase activity|bunolol reductase activity Catalysis of the reaction: dihydrobunolol + NADP(+) = bunolol + H(+) + NADPH. GO:0047854 diguanidinobutanase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047854 MetaCyc:DIGUANIDINOBUTANASE-RXN|KEGG_REACTION:R01418|RHEA:13597|EC:3.5.3.20 1,4-diguanidinobutane amidinohydrolase activity Catalysis of the reaction: 1,4-diguanidinobutane + H(2)O = agmatine + urea. GO:0047853 difructose-anhydride synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047853 EC:3.2.1.134|RHEA:15041|MetaCyc:DIFRUCTOSE-ANHYDRIDE-SYNTHASE-RXN inulobiose hydrolase activity|bis-D-fructose 2',1:2,1'-dianhydride fructohydrolase activity Catalysis of the reaction: H2O + bis-D-fructose 2',1:2,1'-dianhydride = inulobiose. GO:0047852 diferric-transferrin reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047852 RHEA:13841|MetaCyc:DIFFERIC-TRANSFERRIN-REDUCTASE-RXN|EC:1.16.1.2 transferrin[Fe(II)]2:NAD+ oxidoreductase activity|diferric transferrin reductase activity|transferrin reductase activity|NADH diferric transferrin reductase activity Catalysis of the reaction: transferrin[Fe2+]2 + NAD+ = transferrin[Fe3+]2 + NADH. UBERON:0015871 facial lymph node biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015871 buccal lymph node Any of the lymph nodes that are part of a face. GO:0047851 dicarboxylate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047851 EC:6.2.1.23|MetaCyc:DICARBOXYLATE--COA-LIGASE-RXN|RHEA:14289 omega-dicarboxylate:CoA ligase (AMP-forming)|carboxylyl-CoA synthetase activity Catalysis of the reaction: ATP + an omega-dicarboxylic acid + CoASH= AMP + diphosphate + an omega-carboxyacyl-CoA. GO:0047850 diaminopimelate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047850 MetaCyc:DIAMINOPIMELATE-DEHYDROGENASE-RXN|EC:1.4.1.16|KEGG_REACTION:R02755|RHEA:13561 meso-diaminopimelate dehydrogenase activity|meso-2,6-diaminoheptanedioate:NADP+ oxidoreductase (deaminating)|meso-alpha,epsilon-diaminopimelate dehydrogenase activity|meso-diaminopimelate D-dehydrogenase activity Catalysis of the reaction: meso-2,6-diaminopimelate + H(2)O + NADP(+) = L-2-amino-6-oxopimelate + H(+) + NADPH + NH(4)(+). GO:0047859 obsolete dihydroxyphenylalanine ammonia-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047859 EC:4.3.1.11 3,4-dihydroxy-L-phenylalanine ammonia-lyase activity|beta-(3,4-dihydroxyphenyl)-L-alanine (DOPA) ammonia-lyase activity|dihydroxyphenylalanine ammonia-lyase activity|3,4-dihydroxy-L-phenylalanine ammonia-lyase (trans-caffeate-forming) OBSOLETE. Catalysis of the reaction: 3,4-dihydroxy-L-phenylalanine = trans-caffeate + NH3. GO:0047858 dihydroxyfumarate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047858 MetaCyc:DIHYDROXYFUMARATE-DECARBOXYLASE-RXN|RHEA:13845|EC:4.1.1.54|KEGG_REACTION:R03127 dihydroxyfumarate carboxy-lyase activity|dihydroxyfumarate carboxy-lyase (tartronate-semialdehyde-forming) Catalysis of the reaction: dihydroxyfumarate + H(+) = 2-hydroxy-3-oxopropanoate + CO(2). GO:0047857 dihydrouracil oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047857 MetaCyc:DIHYDROURACIL-OXIDASE-RXN|KEGG_REACTION:R00975|EC:1.3.3.7|RHEA:12384 5,6-dihydrouracil:oxygen oxidoreductase activity Catalysis of the reaction: 5,6-dihydrouracil + O(2) = H(2)O(2) + uracil. UBERON:0001235 adrenal cortex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001235 suprarenal cortex|cortex (glandula suprarenalis)|adrenal gland cortex|cortex of adrenal gland|cortex of suprarenal gland|suprarenal|cortex glandulae suprarenalis the thick outer layer of the adrenal gland that produces and secretes steroid hormones such as corticosterone, estrone and aldosterone UBERON:0001234 left adrenal gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001234 left suprarenal gland|glandula suprarenalis sinister An adrenal gland that is in the left side of the abdomen UBERON:0001236 adrenal medulla biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001236 medulla of glandula suprarenalis|medulla of adrenal gland|medulla (glandula suprarenalis)|medulla glandulae suprarenalis|adrenal gland medulla|adrenal central medulla|chromaffin cells|suprarenal medulla|medulla of suprarenal gland the inner portion of the adrenal gland that consists mainly of chromaffin cells which produce, store and secrete neurotransmitters such as epinephrine and norepinephrine UBERON:0001231 nephron tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001231 kidney tubule|uriniferous tubule|tubulus renalis|renal tubule An epithelial tube that is part of the nephron, the functional part of the kidney. UBERON:0001230 glomerular capsule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001230 Muellerian capsule|Mueller capsule|Malphigian capsule|pronephric glomerular capsule|Bowmans capsule|Malpighian capsule|Bowman's capsule|capsula glomeruli|Bowman's capsule|renal glomerular capsule|capsula glomerularis A cup-like sac at the expanded beginning of a tubular component of a nephron that contains the glomerulus UBERON:0001233 right adrenal gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001233 glandula suprarenalis dexter|right suprarenal gland An adrenal gland that is in the right side of the abdomen UBERON:0001232 collecting duct of renal tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001232 arcuate renal tubule|collecting tubule|tubulus renalis arcuatus|kidney collecting tubule|collecting duct|ureteric tree|tubulus renalis colligens|kidney collecting duct|junctional tube|collecting duct system|renal collecting tubule The collecting duct is a portion of the nephron through which water flows, moving passively down its concentration gradient CHEBI:24455 guanosine phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24455 CHEBI:48400 3-(3,4-dihydroxyphenyl)propanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48400 CHEBI:48403 UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-mannuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48403 CHEBI:48402 UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48402 CHEBI:48405 1D-myo-inositol 1,2,3,5,6-pentakisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48405 CHEBI:48404 UDP-alpha-D-mannuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48404 CHEBI:24458 guanosines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24458 CHEBI:48407 antiparkinson drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48407 UBERON:0001218 middle colic vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001218 vena colica media (intermedia)|vena colica media The middle colic vein drains the transverse colon. It is a tributary of the superior mesenteric vein, and follows the path of its corresponding artery, the middle colic artery. [WP,unvetted]. GO:0047867 dimethylmalate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047867 MetaCyc:DIMETHYLMALATE-DEHYDROGENASE-RXN|EC:1.1.1.84|KEGG_REACTION:R01211|RHEA:13321 (R)-3,3-dimethylmalate:NAD+ oxidoreductase (decarboxylating)|beta,beta-dimethylmalate dehydrogenase activity Catalysis of the reaction: (R)-3,3-dimethylmalate + NAD(+) = 3-methyl-2-oxobutanoate + CO(2) + NADH. GO:0047866 dimethylglycine oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047866 EC:1.5.3.10|KEGG_REACTION:R01564|RHEA:17077|MetaCyc:DIMETHYLGLYCINE-OXIDASE-RXN N,N-dimethylglycine:oxygen oxidoreductase (demethylating) Catalysis of the reaction: N,N-dimethylglycine + H(2)O + O(2) = formaldehyde + H(2)O(2) + sarcosine. GO:0047865 dimethylglycine dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047865 KEGG_REACTION:R01565|Reactome:R-HSA-6797653|EC:1.5.8.4|MetaCyc:DIMETHYLGLYCINE-DEHYDROGENASE-RXN|RHEA:52856 N,N-dimethylglycine oxidase activity|N,N-dimethylglycine:acceptor oxidoreductase (demethylating)|N,N-dimethylglycine:(acceptor) oxidoreductase (demethylating) Catalysis of the reaction: N,N-dimethylglycine + electron-transfer flavoprotein + H2O = sarcosine + formaldehyde + reduced electron-transfer flavoprotein. GO:0047864 dimethylaniline-N-oxide aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047864 EC:4.1.2.24|KEGG_REACTION:R03345|RHEA:19321|MetaCyc:DIMETHYLANILINE-N-OXIDE-ALDOLASE-RXN microsomal N-oxide dealkylase activity|N,N-dimethylaniline-N-oxide formaldehyde-lyase (N-methylaniline-forming)|microsomal oxidase II|N,N-dimethylaniline-N-oxide formaldehyde-lyase activity Catalysis of the reaction: N,N-dimethylaniline N-oxide = N-methylaniline + formaldehyde. GO:0047863 dimethylallylcistransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047863 RHEA:11328|MetaCyc:DIMETHYLALLYLCISTRANSFERASE-RXN|EC:2.5.1.28|KEGG_REACTION:R01659 dimethylallyl-diphosphate:isopentenyl-diphosphate dimethylallylcistransferase activity|neryl-diphosphate synthase activity Catalysis of the reaction: dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + neryl diphosphate. GO:0047862 diisopropyl-fluorophosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047862 KEGG_REACTION:R01533|EC:3.1.8.2|RHEA:24100|MetaCyc:DIISOPROPYL-FLUOROPHOSPHATASE-RXN isopropylphosphorofluoridase activity|diisopropyl-fluorophosphate fluorohydrolase activity|organophosphate acid anhydrase activity|DFPase activity|tabunase activity|OPA anhydrase activity|diisopropyl phosphorofluoridate hydrolase activity|diisopropylphosphofluoridase activity|organophosphorus acid anhydrolase activity|diisopropylfluorophosphonate dehalogenase activity|somanase activity|OPAA activity|dialkylfluorophosphatase activity Catalysis of the reaction: diisopropyl fluorophosphate + H(2)O = diisopropyl phosphate + 2 H(+) + hydrogen fluoride. UBERON:0015860 visceral abdominal lymph node biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015860 GO:0047861 diiodotyrosine transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047861 KEGG_REACTION:R03207|EC:2.6.1.24|RHEA:19781|MetaCyc:DIIODOTYROSINE-AMINOTRANSFERASE-RXN halogenated tyrosine aminotransferase activity|diiodotyrosine aminotransferase activity|halogenated tyrosine transaminase activity|3,5-diiodo-L-tyrosine:2-oxoglutarate aminotransferase activity Catalysis of the reaction: 2-oxoglutarate + 3,5-diiodo-L-tyrosine = 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate + L-glutamate. GO:0047860 diiodophenylpyruvate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047860 EC:1.1.1.96|MetaCyc:DIIODOPHENYLPYRUVATE-REDUCTASE-RXN|KEGG_REACTION:R03431|RHEA:20293 2-oxo acid reductase activity|KAR|3-(3,5-diiodo-4-hydroxyphenyl)lactate:NAD+ oxidoreductase activity|aromatic alpha-keto acid Catalysis of the reaction: 3-(3,5-diiodo-4-hydroxyphenyl)lactate + NAD(+) = 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate + H(+) + NADH. GO:0047869 dimethylpropiothetin dethiomethylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047869 MetaCyc:DIMETHYLPROPIOTHETIN-DETHIOMETHYLASE-RXN|KEGG_REACTION:R02574|RHEA:19965|EC:4.4.1.3 S,S-dimethyl-beta-propiothetin dimethyl-sulfide-lyase activity|S,S-dimethyl-beta-propiothetin dimethyl-sulfide-lyase (acrylate-forming)|desulfhydrase activity Catalysis of the reaction: S,S-dimethyl-beta-propiothetin = acrylate + dimethyl sulfide + H(+). GO:0047868 dimethylmaleate hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047868 EC:4.2.1.85|RHEA:20253|KEGG_REACTION:R03069|MetaCyc:DIMETHYLMALEATE-HYDRATASE-RXN (2R,3S)-2,3-dimethylmalate hydro-lyase activity|(2R,3S)-2,3-dimethylmalate hydro-lyase (dimethylmaleate-forming) Catalysis of the reaction: (2R,3S)-2,3-dimethylmalate = dimethylmaleate + H(2)O. UBERON:0001224 renal pelvis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001224 pyelum|kidney pelvis|p. renallis|pelvis of ureter A funnel shaped proximal portion of the ureter that is formed by convergence of the major calices [MP]. UBERON:0001223 left ureter biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001223 An ureter that is part of a left side of organism [Automatically generated definition]. UBERON:0001225 cortex of kidney biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001225 kidney cortex|renal cortex|cortex renalis Outer cortical portion of the kidney, between the renal capsule and the renal medulla. UBERON:0001222 right ureter biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001222 An ureter that is part of a right side of organism [Automatically generated definition]. GO:0047870 discadenine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047870 RHEA:19581|MetaCyc:DISCADENINE-SYNTHASE-RXN|KEGG_REACTION:R03726|EC:2.5.1.24 S-adenosyl-L-methionine:6-N-(Delta2-isopentenyl)-adenine 3-(3-amino-3-carboxypropyl)-transferase activity|S-adenosyl-L-methionine:N6-(Delta2-isopentenyl)-adenine 3-(3-amino-3-carboxypropyl)-transferas|discadenine synthetase activity Catalysis of the reaction: N(6)-dimethylallyladenine + S-adenosyl-L-methionine(1+) = S-methyl-5'-thioadenosine + discadenine + H(+). UBERON:0001209 serosa of large intestine biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001209 large intestine serous membrane|serous coat of large intestine|tunica serosa intestini crassi|visceral peritoneum of large intestine|large intestine serosa|serous membrane of large intestine|large intestinal serosa A serous membrane that is part of a large intestine [Automatically generated definition]. CHEBI:73477 terminal acetylenic compound biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73477 UBERON:0001206 serosa of small intestine biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001206 small intestine serosa|visceral peritoneum of small intestine|serous membrane of small bowel|small bowel serosa|serous membrane of small intestine|small bowel serous membrane|small intestinal serosa|tunica serosa (intestinum tenue)|small intestine serous membrane|serous coat of small intestine|serosa of small bowel|tunica serosa intestini tenuis A serous membrane that is part of a small intestine [Automatically generated definition]. UBERON:0001205 submucosa of small intestine biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001205 tela submucosa intestini tenuis|submucosa of small bowel|small intestinal submucosa|small bowel submucosa|tela submucosa (intestinum tenue)|small intestine submucosa submucosal tissue in the small intestines. UBERON:0001208 submucosa of large intestine biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001208 large intestinal submucosa|large intestine submucosa|tela submucosa intestini crassi|submucous layer of large intestine A submucosa that is part of a large intestine [Automatically generated definition]. UBERON:0001207 mucosa of large intestine biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001207 large intestine organ mucosa|organ mucosa of large intestine|large intestine mucosa of organ|large intestine mucous membrane|tunica mucosa intestini crassi|large intestine mucosa|mucous membrane of large intestine|large intestinal mucosa|mucosa of organ of large intestine A mucosa that is part of a large intestine [Automatically generated definition]. GO:0047878 erythritol kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047878 MetaCyc:ERYTHRITOL-KINASE-RXN|RHEA:20708|EC:2.7.1.27|KEGG_REACTION:R02430 ATP:erythritol 4-phosphotransferase activity|erythritol kinase (phosphorylating) Catalysis of the reaction: ATP + erythritol = D-erythritol 4-phosphate + ADP + 2 H(+). GO:0047877 ephedrine dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047877 MetaCyc:EPHEDRINE-DEHYDROGENASE-RXN|EC:1.5.1.18|KEGG_REACTION:R03614|RHEA:16289 (-)-ephedrine:NAD+ 2-oxidoreductase activity Catalysis of the reaction: (1R,2S)-ephedrine + NAD(+) = (R)-2-methylimino-1-phenylpropan-1-ol + 2 H(+) + NADH. GO:0047876 endoglycosylceramidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047876 RHEA:22288|MetaCyc:ENDOGLYCOSYLCERAMIDASE-RXN|EC:3.2.1.123 glycosyl-N-acetyl-sphingosine 1,1-beta-D-glucanohydrolase activity|endo-glucosylceramidase activity|oligoglycosylglucosylceramide glycohydrolase activity|endoglycoceramidase activity|EGCase activity Catalysis of the reaction: H2O + oligoglycosylglucosylceramide = ceramide + oligoglycosylglucose. GO:0047875 ecdysone oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047875 EC:1.1.3.16|MetaCyc:ECDYSONE-OXIDASE-RXN|RHEA:11796|KEGG_REACTION:R02373 beta-ecdysone oxidase activity|ecdysone:oxygen 3-oxidoreductase activity Catalysis of the reaction: Ecdysone + O(2) = 3-dehydroecdysone + H(2)O(2). GO:0047874 dolichyldiphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047874 Reactome:R-HSA-446200|MetaCyc:DOLICHYLDIPHOSPHATASE-RXN|EC:3.6.1.43|RHEA:14385 dolichyl-diphosphate phosphohydrolase activity|dolichol diphosphatase activity|dolichyl diphosphate phosphohydrolase activity|dolichyl pyrophosphatase activity Catalysis of the reaction: dolichyl diphosphate + H2O = dolichyl phosphate + phosphate. GO:0047873 dolichyl-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047873 MetaCyc:DOLICHYL-PHOSPHATASE-RXN|RHEA:13797|EC:3.1.3.51 Dol-P phosphatase activity|dolichol monophosphatase activity|dolichol phosphate phosphatase activity|dolichol phosphatase activity|Dol-P-P phosphohydrolase activity|polyprenylphosphate phosphatase activity|polyisoprenyl phosphate phosphatase activity|dolichyl pyrophosphate phosphatase activity|dolichyl monophosphate phosphatase activity|dolichyl phosphate phosphatase activity|dolichyl-phosphate phosphohydrolase activity Catalysis of the reaction: dolichyl phosphate + H2O = dolichol + phosphate. GO:0047872 dolichol O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047872 MetaCyc:DOLICHOL-O-ACYLTRANSFERASE-RXN|RHEA:16685|EC:2.3.1.123 acyl-CoA:dolichol acyltransferase activity|palmitoyl-CoA:dolichol O-palmitoyltransferase activity Catalysis of the reaction: palmitoyl-CoA + dolichol = CoA + dolichyl palmitate. GO:0047871 disulfoglucosamine-6-sulfatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047871 MetaCyc:DISULFOGLUCOSAMINE-6-SULFATASE-RXN|RHEA:15517|KEGG_REACTION:R03216|EC:3.1.6.11 6,N-disulfoglucosamine 6-O-sulfohydrolase activity|disulphoglucosamine-6-sulphatase activity|N,6-O-disulfo-D-glucosamine 6-sulfohydrolase activity|N-sulfoglucosamine-6-sulfatase activity Catalysis of the reaction: N(2),6-disulfo-D-glucosamine + H(2)O = N-sulfo-D-glucosamine + H(+) + sulfate. GO:0047879 erythronolide synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047879 MetaCyc:ERYTHRONOLIDE-SYNTHASE-RXN|EC:2.3.1.94|RHEA:23068 erythronolide condensing enzyme activity|malonyl-CoA:propionyl-CoA malonyltransferase (cyclizing) Catalysis of the reaction: 6 malonyl-CoA + propionyl-CoA = 7 CoA + 6-deoxyerythronolide B. UBERON:0001213 intestinal villus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001213 small intestine villus|villi intestinales|intestinal villus layer|villus|enteric villous|enteric villi|villus intestinalis (intestinum tenue)|enteric villus|villi intestinales|intestinal villi the tiny hair-like projections that protrude from the inside of the small intestine that contain blood vessels that capture digested nutrients that are absorbed through the intestinal wall; the villi increase the absorptive surface area of the small intestine by approximately 30-fold UBERON:0001212 duodenal gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001212 gland of Brunner|Brunner's gland|submucosal gland of duodenum|glandula duodenales|glandula duodenales Brunneri A compound tubular submucosal gland found in that portion of the duodenum which is above the hepatopancreatic sphincter (Sphincter of Oddi). The main function of these glands is to produce a mucus-rich alkaline secretion (containing bicarbonate)[WP]. UBERON:0001215 inferior mesenteric vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001215 lower mesenteric vein|vena mesenterica inferior A blood vessel that drains blood from the large intestine that usually terminates when reaching the splenic vein, which goes on to form the portal vein with the superior mesenteric vein (SMV). Anatomical variations include the IMV draining into the confluence of the SMV and splenic vein and the IMV draining in the SMV. The IMV lies to the right of the similarly name artery, the inferior mesenteric artery, which originates from the abdominal aorta. [WP,unvetted]. CHEBI:73474 acetylenic compound biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73474 UBERON:0001211 Peyer's patch biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001211 aggregated lymphoid nodule|Peyers gland|aggregated lymphoid follicle of intestine|noduli lymphoidei aggregati|Peyers patch the protruding lymphoid tissue located on the mucosa of the intestine that is composed of densely packed B cell follicles GO:0047881 estradiol 17-alpha-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047881 EC:1.1.1.148|MetaCyc:ESTRADIOL-17-ALPHA-DEHYDROGENASE-RXN estradiol 17alpha-oxidoreductase activity|17alpha-hydroxysteroid oxidoreductase activity|estradiol 17alpha-dehydrogenase activity|17alpha-estradiol dehydrogenase activity|17alpha-hydroxysteroid:NAD(P)+ 17-oxidoreductase activity|17alpha-hydroxy steroid oxidoreductase activity|estradiol 17a-dehydrogenase activity|17alpha-hydroxy steroid dehydrogenase activity Catalysis of the reaction: estradiol-17-alpha + NAD(P)+ = estrone + NAD(P)H + H+. GO:0047880 erythrulose reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047880 RHEA:18005|KEGG_REACTION:R08573|EC:1.1.1.162|MetaCyc:ERYTHRULOSE-REDUCTASE-RXN erythritol:NADP+ oxidoreductase activity|D-erythrulose reductase activity Catalysis of the reaction: D-threitol + NADP(+) = D-erythrulose + H(+) + NADPH. CHEBI:24433 group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24433 CHEBI:24432 biological role biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24432 CHEBI:24431 chemical entity biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_24431 CHEBI:24436 guanidines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24436 GO:0047889 ferredoxin-nitrate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047889 MetaCyc:1.7.7.2-RXN|EC:1.7.7.2|RHEA:21828 nitrite:ferredoxin oxidoreductase activity|assimilatory nitrate reductase activity|nitrate (ferredoxin) reductase activity|assimilatory ferredoxin-nitrate reductase activity Catalysis of the reaction: nitrite + H2O + 2 oxidized ferredoxin = nitrate + 2 reduced ferredoxin. GO:0047888 fatty acid peroxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047888 RHEA:23960|EC:1.11.1.3|MetaCyc:FATTY-ACID-PEROXIDASE-RXN|KEGG_REACTION:R01703 hexadecanoate:hydrogen-peroxide oxidoreductase activity|long chain fatty acid peroxidase activity|fatty-acid peroxidase activity Catalysis of the reaction: 2 H(2)O(2) + H(+) + palmitate = CO(2) + 3 H(2)O + pentadecanal. GO:0047887 farnesyl diphosphate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047887 KEGG_REACTION:R02303|RHEA:21544|MetaCyc:FARNESYL-DIPHOSPHATE-KINASE-RXN|EC:2.7.4.18 farnesyl-diphosphate kinase activity|ATP:farnesyl-diphosphate phosphotransferase activity|farnesyl pyrophosphate kinase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + ATP = 2-trans,6-trans-farnesyl triphosphate + ADP. GO:0047886 farnesol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047886 RHEA:14697|KEGG_REACTION:R03264|EC:1.1.1.216|MetaCyc:FARNESOL-DEHYDROGENASE-RXN farnesol (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity|2-trans,6-trans-farnesol:NADP+ 1-oxidoreductase activity|NADP-farnesol dehydrogenase activity Catalysis of the reaction: 2-trans,6-trans-farnesol + NADP(+) = 2-trans,6-trans-farnesal + H(+) + NADPH. GO:0047885 farnesol 2-isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047885 RHEA:13401|EC:5.2.1.9|KEGG_REACTION:R03265|MetaCyc:FARNESOL-2-ISOMERASE-RXN 2-trans,6-trans-farnesol 2-cis-trans-isomerase activity|farnesol isomerase activity Catalysis of the reaction: 2-trans,6-trans-farnesol = 2-cis,6-trans-farnesol. GO:0047884 FAD diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047884 MetaCyc:FAD-PYROPHOSPHATASE-RXN|EC:3.6.1.18|RHEA:13889 flavine adenine dinucleotide pyrophosphatase activity|riboflavin adenine dinucleotide pyrophosphatase activity|riboflavine adenine dinucleotide pyrophosphatase activity|FAD nucleotidohydrolase activity|flavin adenine dinucleotide pyrophosphatase activity|FAD pyrophosphatase activity|FAD pyrophosphohydrolase activity Catalysis of the reaction: FAD + H2O = AMP + FMN. GO:0047883 ethanolamine oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047883 EC:1.4.3.8|MetaCyc:ETHANOLAMINE-OXIDASE-RXN|RHEA:18581 ethanolamine:oxygen oxidoreductase (deaminating) Catalysis of the reaction: ethanolamine + H2O + O2 = glycolaldehyde + NH3 + H2O2. GO:0047882 estradiol 6-beta-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047882 MetaCyc:ESTRADIOL-6-BETA-MONOOXYGENASE-RXN|RHEA:19137|KEGG_REACTION:R03086|EC:1.14.99.11 estradiol-17beta,hydrogen-donor:oxygen oxidoreductase (6beta-hydroxylating)|estradiol 6-beta-hydroxylase activity|estradiol 6beta-monooxygenase activity|estradiol 6beta-hydroxylase activity|estradiol 6b-monooxygenase activity|estradiol 6b-hydroxylase activity Catalysis of the reaction: AH(2) + estradiol-17beta + O(2) = 6beta-hydroxyestradiol-17beta + A + H(2)O. UBERON:0001202 pyloric sphincter biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001202 pyloric valve A strong ring of smooth muscle at the end of the pyloric canal which lets food pass from the stomach to the duodenum. It receives sympathetic innervation from the celiac ganglion[WP]. UBERON:0001201 serosa of stomach biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001201 serosa of ventriculus anatomical wall|serous membrane of ventriculus wall|serous coat of stomach|serous membrane of anatomical wall of ventriculus|ventriculus anatomical wall serosa|serous membrane of wall of ventriculus|stomach wall serous membrane|wall of stomach serosa|serosa of stomach wall|serous membrane of gastric wall|serosa of stomach anatomical wall|gastric serosa|anatomical wall of stomach serosa|serous membrane of anatomical wall of stomach|serous membrane of wall of stomach|gastric wall serosa|serosa of ventriculus wall|ventriculus wall serous membrane|serous membrane of ventriculus anatomical wall|wall of ventriculus serosa|visceral peritoneum of stomach|serosa of anatomical wall of ventriculus|anatomical wall of ventriculus serous membrane|anatomical wall of ventriculus serosa|wall of ventriculus serous membrane|serosa of gastric wall|ventriculus wall serosa|serous membrane of stomach anatomical wall|gastric wall serous membrane|anatomical wall of stomach serous membrane|serosa of anatomical wall of stomach|wall of stomach serous membrane|stomach wall serosa|ventriculus anatomical wall serous membrane|tunica serosa gastricae|tunica serosa (gaster)|stomach serosa|stomach anatomical wall serous membrane|serosa of wall of ventriculus|serous membrane of stomach wall|stomach anatomical wall serosa|serosa of wall of stomach the outermost layer of the stomach wall, consisting of layers of connective tissue continuous with the peritoneum UBERON:0001204 mucosa of small intestine biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001204 mucous membrane of small bowel|mucosa of small bowel|tunica mucosa intestini tenuis|small bowel mucosa|mucosa of organ of small bowel|mucous membrane of small intestine|small intestinal mucosa|small intestine organ mucosa|mucosa of organ of small intestine|organ mucosa of small bowel|small bowel mucosa of organ|small bowel organ mucosa|small bowel mucous membrane|tunica mucosa (intestinum tenue)|small intestine mucosa of organ|organ mucosa of small intestine|small intestine mucosa|small intestine mucous membrane A mucosa that is part of a small intestine [Automatically generated definition]. CHEBI:73483 grixazone B(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73483 CHEBI:73482 grixazone A(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73482 CHEBI:24439 guanidinoacetic acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24439 UBERON:0001200 submucosa of stomach biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001200 stomach submucosa|submucosa of ventriculus|tela submucosa gastricae|submucous layer of stomach|gastric submucosa|tela submucosa (gaster)|tela submucosa ventriculi|ventriculus submucosa the fibrous connective tissue layer beneath the stomach mucosa UBERON:4200172 neck of humerus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_4200172 anatomic neck of humerus|collum anatomicum (Humerus)|collum anatomicum humeri|humeral neck GO:0033249 positive regulation of penicillin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033249 positive regulation of penicillin degradation|positive regulation of penicillin catabolism|positive regulation of penicillin breakdown Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system. CHEBI:143788 N(1)-(5-phospho-beta-D-ribosyl)glycinamide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_143788 GO:0008289 lipid binding biolink:MolecularActivity go-plus goslim_flybase_ribbon|goslim_chembl|goslim_mouse|goslim_candida|goslim_agr|goslim_yeast|goslim_pir|goslim_plant|goslim_drosophila|goslim_generic http://purl.obolibrary.org/obo/GO_0008289 Interacting selectively and non-covalently with a lipid. GO:0008288 boss receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008288 sevenless receptor activity Combining with a protein bride of sevenless (boss) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate. GO:0008287 protein serine/threonine phosphatase complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0008287 A complex, normally consisting of a catalytic and a regulatory subunit, which catalyzes the removal of a phosphate group from a serine or threonine residue of a protein. GO:0008286 insulin receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008286 daf-2 receptor signaling pathway|insulin receptor signalling pathway The series of molecular signals generated as a consequence of the insulin receptor binding to insulin. GO:0008285 negative regulation of cell population proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008285 down-regulation of cell proliferation|negative regulation of cell proliferation|downregulation of cell proliferation|down regulation of cell proliferation|inhibition of cell proliferation Any process that stops, prevents or reduces the rate or extent of cell proliferation. GO:0033240 positive regulation of cellular amine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033240 positive regulation of amine metabolism Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amines. GO:0008295 spermidine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008295 MetaCyc:POLYAMINSYN3-PWY|MetaCyc:BSUBPOLYAMSYN-PWY spermidine anabolism|spermidine synthesis|spermidine formation|spermidine biosynthesis The chemical reactions and pathways resulting in the formation of spermidine, N-(3-aminopropyl)-1,4-diaminobutane. GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008294 Reactome:R-HSA-111930|Reactome:R-HSA-442715 calcium/calmodulin-responsive adenylate cyclase activity|calcium- and calmodulin-responsive adenylyl cyclase activity Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate, stimulated by calcium-bound calmodulin. GO:0008293 torso signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008293 torso signalling pathway A series of molecular signals initiated by the binding of an extracellular ligand to torso (a receptor tyrosine kinase) on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0008292 acetylcholine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008292 acetylcholine anabolism|acetylcholine biosynthesis|acetylcholine synthesis|acetylcholine formation The chemical reactions and pathways resulting in the formation of acetylcholine, the acetic acid ester of the organic base choline. GO:0008291 acetylcholine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008291 acetylcholine metabolism The chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues. GO:0008290 F-actin capping protein complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0008290 A heterodimer consisting of alpha and beta subunits that binds to and caps the barbed ends of actin filaments, thereby regulating the polymerization of actin monomers but not severing actin filaments. GO:0033248 negative regulation of penicillin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033248 negative regulation of penicillin degradation|negative regulation of penicillin breakdown|negative regulation of penicillin catabolism Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system. GO:0033247 regulation of penicillin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033247 regulation of penicillin catabolism|regulation of penicillin degradation|regulation of penicillin breakdown Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system. GO:0033246 positive regulation of penicillin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033246 positive regulation of penicillin metabolism Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system. GO:0033245 negative regulation of penicillin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033245 negative regulation of penicillin metabolism Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system. GO:0033244 regulation of penicillin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033244 regulation of penicillin metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system. GO:0033243 positive regulation of cellular amine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033243 positive regulation of amine breakdown|positive regulation of amine catabolism|positive regulation of amine degradation Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines. GO:0033242 negative regulation of cellular amine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033242 negative regulation of amine degradation|negative regulation of amine catabolism|negative regulation of amine breakdown Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines. GO:0033241 regulation of cellular amine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033241 regulation of amine catabolism|regulation of amine degradation|regulation of amine breakdown Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines. GO:0033239 negative regulation of cellular amine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033239 negative regulation of amine metabolism Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines. GO:0033238 regulation of cellular amine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033238 regulation of amine metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines. GO:0008299 isoprenoid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008299 MetaCyc:POLYISOPRENSYN-PWY polyisoprenoid anabolism|polyisoprenoid synthesis|polyisoprenoid formation|isoprenoid anabolism|isoprenoid biosynthesis|polyterpene biosynthetic process|polyterpene biosynthesis|isoprenoid synthesis|isoprenoid formation|polyisoprenoid biosynthesis|polyisoprenoid biosynthetic process The chemical reactions and pathways resulting in the formation of any isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues. GO:0008298 intracellular mRNA localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008298 establishment and maintenance of intracellular RNA localization|mRNA localization, intracellular|intracellular mRNA positioning|intracellular mRNA localisation|mRNA positioning, intracellular Any process in which mRNA is transported to, or maintained in, a specific location within the cell. GO:0008297 single-stranded DNA exodeoxyribonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008297 ssDNA-specific exodeoxyribonuclease activity|single-stranded DNA specific exodeoxyribonuclease activity Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a single-stranded DNA molecule. GO:0008296 3'-5'-exodeoxyribonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008296 Reactome:R-HSA-9023943 3'-5' exodeoxyribonuclease activity Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a DNA molecule. GO:0033237 obsolete 11-beta-hydroxysteroid dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033237 11beta-hydroxysteroid:NADP+ 11-oxidoreductase|corticosteroid 11-beta-dehydrogenase activity|beta-hydroxysteroid dehydrogenase|11-beta-hydroxysteroid dehydrogenase (NADP+) activity OBSOLETE. Catalysis of the reaction: an 11-beta-hydroxysteroid + NADP+ = an 11-oxosteroid + NADPH + H+. GO:0033236 obsolete 11-beta-hydroxysteroid dehydrogenase (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033236 11-beta-hydroxysteroid dehydrogenase (NAD+) activity OBSOLETE. Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD+ = an 11-oxosteroid + NADH + H+. GO:0033235 positive regulation of protein sumoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033235 positive regulation of sumoylation Any process that activates or increases the frequency, rate or extent of the addition of SUMO groups to a protein. GO:0033234 negative regulation of protein sumoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033234 negative regulation of sumoylation Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of SUMO groups to a protein. GO:0033233 regulation of protein sumoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033233 regulation of sumoylation Any process that modulates the frequency, rate or extent of the addition of SUMO groups to a protein. GO:0033232 ABC-type D-methionine transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033232 RHEA:29779|EC:7.4.2.11 D-methionine-importing ATPase activity|D-methionine exporter|D-methionine-transporting ATPase activity|D-methionine transmembrane transporter activity|D-methionine transporter activity|ATP-dependent methionine transmembrane transporter activity|D-methionine-exporting ATPase activity|ATPase-coupled methionine transmembrane transporter activity|D-methionine importer|methionine transmembrane-transporting ATPase activity|ATP-dependent D-methionine transporter activity|ATPase-coupled D-methionine transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-methionine(out/in) = ADP + phosphate + D-methionine(in/out). GO:0033231 carbohydrate export biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033231 The directed movement of carbohydrates out of a cell or organelle. GO:0033230 ATPase-coupled cysteine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033230 RHEA:32795 ATPase-coupled cysteine transporter activity|cysteine-transporting ATPase activity|cysteine exporter|cysteine-exporting ATPase activity|ATP-dependent cysteine transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cysteine(out/in) = ADP + phosphate + cysteine(in/out). GO:0033229 cysteine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033229 Enables the transfer of cysteine from one side of a membrane to the other. GO:0033228 cysteine export across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033228 cysteine export The directed movement of cysteine from inside of a cell, across the plasma membrane and into the extracellular region. GO:0033227 dsRNA transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033227 The directed movement of dsRNA, double-stranded ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0008269 JAK pathway signal transduction adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008269 The binding activity of a molecule that brings together two molecules of the JAK signal transduction pathway, permitting them to function in a coordinated way. GO:0008268 obsolete receptor signaling protein tyrosine kinase signaling protein activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008268 receptor signalling protein tyrosine kinase signalling protein activity|receptor signaling protein tyrosine kinase signaling protein activity OBSOLETE. (Was not defined before being made obsolete). GO:0008267 poly-glutamine tract binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008267 Interacting selectively and non-covalently with a polyglutamine tract, i.e. a series of consecutive glutamine residues, in a protein. GO:0008266 poly(U) RNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008266 poly(U) binding Interacting selectively and non-covalently with a sequence of uracil residues in an RNA molecule. GO:0008265 Mo-molybdopterin cofactor sulfurase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008265 EC:2.8.1.9|Reactome:R-HSA-947499 molybdopterin cofactor sulfurase activity|Mo-molybdopterin cofactor sulphurase activity|molybdopterin synthase sulfurylase activity Catalysis of the sulfurylation of the desulfo form of molybdenum cofactor (MoCo), a cofactor required for the activity of some enzymes, such as aldehyde oxidase. CHEBI:128120 19-(4-hydroxyphenyl)nonadecanoyl-AMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_128120 GO:0008264 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008264 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008263 G/T-mismatch-specific thymine-DNA glycosylase activity Catalysis of the removal of mismatched pyrimidine bases in DNA. Enzymes with this activity recognize and remove pyrimidines present in mismatches by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apyrimidinic (AP) site. GO:0008273 calcium, potassium:sodium antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008273 Reactome:R-HSA-5625841|Reactome:R-HSA-5626356|Reactome:R-HSA-5626270|Reactome:R-HSA-425678|Reactome:R-HSA-5626316|Reactome:R-HSA-2514891 potassium-dependent sodium/calcium exchanger Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + K+(in) + Na+(out) = Ca2+(out) + K+(out) + Na+(in). GO:0008272 sulfate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008272 sulphate transport The directed movement of sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0008271 secondary active sulfate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008271 secondary active sulphate transmembrane transporter activity|sulfate porter activity|sulphate porter activity Enables the secondary active transfer of sulfate from one side of a membrane to the other. Secondary active transport is the transfer of a solute across a membrane, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. GO:0008270 zinc ion binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008270 zinc binding Interacting selectively and non-covalently with zinc (Zn) ions. GO:0033226 2-aminoethylphosphonate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033226 ciliatine binding|2-phosphonoethylamine binding Interacting selectively and non-covalently with 2-aminoethylphosphonate. GO:0033225 ATPase-coupled 2-aminoethylphosphonate transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033225 RHEA:32775 2-aminoethylphosphonate transmembrane transporter activity|2-aminoethylphosphonate transporting ATPase activity|ATP-dependent 2-aminoethylphosphonate transporter activity|2-phosphonoethylamine transmembrane transporter activity|ciliatine transportingATPase activity|ciliatine transporter activity|2-phosphonoethylamine transporting ATPase activity|2-aminoethylphosphonate-transporting ATPase activity Enables the directed movement of 2-aminoethylphosphonate from one side of a membrane to the other by catalysis of the reaction: ATP + H2O + 2-aminoethylphosphonate(out) = ADP + phosphate + 2-aminoethylphosphonate(in). OBA:VT0004391 respiratory conducting tube morphology trait biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_VT0004391 morphology of respiratory tube The morphology of a respiratory tube. GO:0033224 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0033224 GO:0033223 2-aminoethylphosphonate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033223 ciliatine transport|2-phosphonoethylamine transport The directed movement of 2-aminoethylphosphonate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0033222 xylose binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033222 Interacting selectively and non-covalently with the D- or L-enantiomer of xylose. GO:0033221 ATPase-coupled urea transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033221 RHEA:32803 ATP-dependent urea transmembrane transporter activity|carbamide-transporting ATPase activity|urea-transporting ATPase activity Catalysis of the reaction: ATP + H2O + urea(out) = ADP + phosphate + urea(in). GO:0033220 obsolete ATPase-coupled amide-transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033220 amide-transporting ATPase activity|ATP-dependent amide-transporter activity OBSOLETE. Catalysis of the reaction: ATP + H2O + amide(out) = ADP + phosphate + amide(in). GO:0033219 urea binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033219 Interacting selectively and non-covalently with urea, a water-soluble carboxamide with the structure H2N-CO-NH2. GO:0033218 amide binding biolink:MolecularActivity go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0033218 Interacting selectively and non-covalently with an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group. GO:0033217 regulation of transcription from RNA polymerase II promoter in response to iron ion starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033217 regulation of transcription from RNA polymerase II promoter in response to iron deficiency Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of iron ions. GO:0033216 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0033216 GO:0008279 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008279 GO:0008278 cohesin complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0008278 14S cohesin|Smc1-Smc3 complex|cohesin core heterodimer|SMC complex|SMC/kleisin ring complex|9S cohesin A protein complex that is required for sister chromatid cohesion in eukaryotes. The cohesin complex forms a molecular ring complex, and is composed of structural maintenance of chromosomes (SMC) and kleisin proteins. For example, in yeast, the complex is composed of the SMC proteins Smc1p and Smc3p, and the kleisin protein Scc1p. In vertebrates, the complex is composed of the SMC1 (SMC1A or SMC1B) and SMC3 heterodimer attached via their hinge domains to a kleisin (RAD21, REC8 or RAD21L) which links them, and one STAG protein (STAG1, STAG2 or STAG3). GO:0008277 regulation of G protein-coupled receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008277 regulation of G protein coupled receptor protein signalling pathway|regulation of GPCR protein signalling pathway|regulation of G-protein coupled receptor protein signalling pathway|regulation of G-protein coupled receptor protein signaling pathway|regulation of GPCR protein signaling pathway|regulation of G-protein-coupled receptor protein signalling pathway|regulation of G protein coupled receptor protein signaling pathway Any process that modulates the frequency, rate or extent of G protein-coupled receptor signaling pathway. GO:0008276 protein methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008276 Reactome:R-HSA-9632182 Catalysis of the transfer of a methyl group (CH3-) to a protein. GO:0008275 gamma-tubulin small complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0008275 gammaTuSC A complex usually comprising two gamma-tubulin molecules and two conserved non-tubulin proteins. Some gamma-tubulin small complexes are thought to be the repeating unit making up the core of the gamma-tubulin ring complex. GO:0008274 gamma-tubulin ring complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0008274 gammaTuRC A multiprotein complex composed of gamma-tubulin and other non-tubulin proteins that forms a flexible open ring structure thought to be the unit of nucleation at the minus end of a microtubule. GO:0008284 positive regulation of cell population proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008284 activation of cell proliferation|up-regulation of cell proliferation|up regulation of cell proliferation|positive regulation of cell proliferation|upregulation of cell proliferation|stimulation of cell proliferation Any process that activates or increases the rate or extent of cell proliferation. NCBITaxon:1206795 Lophotrochozoa organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_1206795 GO:0008283 cell population proliferation biolink:BiologicalProcess go-plus goslim_chembl|goslim_mouse|goslim_agr|goslim_pir|goslim_drosophila|goslim_generic|goslim_flybase_ribbon http://purl.obolibrary.org/obo/GO_0008283 cell proliferation The multiplication or reproduction of cells, resulting in the expansion of a cell population. NCBITaxon:1206794 Ecdysozoa organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_1206794 GO:0008282 inward rectifying potassium channel biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0008282 Kir6.1-SUR complex|KCNJ8-SUR complex|Kir6-SUR complex|ATP-sensitive potassium channel complex|KCNJ11-SURx complex|KCNJ11-SUR complex|KCNJ8-SURx complex|Kir6.1-SURx complex|Kir6.2-SURx complex|inward rectifying K+ channel|Kir6.x complex|Kir6.x-SURx complex|Kir6.2-SUR complex A protein complex that comprises four pore-forming (Kir6.x) and four regulatory sulphonylurea receptor (SURx) subunits and forms a transmembrane channel through which ions may pass. The opening and closing of the channel is regulated by ATP: binding of ATP to the Kir6.x subunit inhibits channel activity, whereas binding of Mg2+-complexed ATP or ADP to the SURx subunit stimulates channel activity. GO:0008281 sulfonylurea receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008281 sulphonylurea receptor activity Combining with sulfonylurea, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0008280 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008280 GO:0033215 reductive iron assimilation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033215 iron assimilation by reduction and transport A process in which iron is solubilized by reduction from Fe3+ to Fe2+ via a cell surface reductase and subsequent transport of the iron across the membrane by iron uptake proteins. GO:0033214 siderophore-dependent iron import into cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033214 iron assimilation by capture and transport|iron chelate transport|iron assimilation by chelation and transport A process in which iron (Fe3+) is solubilized by ferric iron-specific chelators, known as siderophores, excreted by a cell; the iron-siderophore complex is then transported into the cell by specific cell surface receptors. GO:0033213 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0033213 GO:0033212 iron import into cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033212 ferrous ion import|ferrous iron import|ferrous iron uptake|iron assimilation The directed movement of iron ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis. GO:0033211 adiponectin-activated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033211 adipocytokine signaling pathway|adiponectin-mediated signaling pathway|adiponectin-mediated signalling pathway A series of molecular signals initiated by the binding of adiponectin to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0033210 leptin-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033210 leptin-mediated signalling pathway|adipocytokine signaling pathway A series of molecular signals initiated by the binding of leptin to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body. GO:0033209 tumor necrosis factor-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033209 adipocytokine signaling pathway|TNF-alpha-mediated signaling pathway|tumor necrosis factor alpha-mediated signaling pathway|tumor necrosis factor-mediated signalling pathway A series of molecular signals initiated by the binding of a tumor necrosis factor to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0033208 UDP-N-acetylgalactosamine:N-acetylneuraminyl-alpha-2,3-galactosyl-beta-R 1,4-N-acetylgalactosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033208 UDP-GalNAc:Neu5Ac-alpha-2-Gal-beta-1-R beta-1,4-N-acetylgalactosaminyltransferase activity|Sda beta 1,4GalNAc transferase Catalysis of the reaction: UDP-N-acetylgalactosamine + N-acetylneuraminyl-alpha-2,3-galactosyl-beta-oligosaccharide = UDP + N-acetylgalactosaminyl-N-acetylneuraminyl-alpha-2,3-galactosyl-beta-oligosaccharide. GO:0033207 beta-1,4-N-acetylgalactosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033207 beta-1,4-GalNAc transferase activity Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an acceptor molecule, forming a beta-1,4 linkage. GO:0033206 meiotic cytokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033206 cytokinesis after meiosis A cell cycle process that results in the division of the cytoplasm of a cell after meiosis, resulting in the separation of the original cell into two daughter cells. GO:0033205 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0033205 GO:0008249 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008249 GO:0008248 obsolete pre-mRNA splicing factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008248 pre-mRNA splicing factor activity OBSOLETE. An activity involved in the removal of an intron from a pre-mRNA. GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0008247 platelet-activating factor acetylhydrolase complex|2-acetyl-1-alkylglycerophosphocholine esterase complex An enzyme complex composed of two catalytic alpha subunits, which form a catalytic dimer, and a non-catalytic, regulatory beta subunit; the catalytic dimer may be an alpha1/alpha1 or alpha2/alpha2 homodimer, or an alpha1/alpha2 heterodimer. Modulates the action of platelet-activating factor (PAF). GO:0008246 obsolete electron transfer flavoprotein biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008246 ETF|electron transfer flavoprotein OBSOLETE. Works in conjunction with acyl-CoA dehydrogenase to catalyze the oxidation of CoA and reduce ubiquinone. Part of the mitochondrial electron transport system. GO:0008245 obsolete lysosomal membrane hydrogen-transporting ATPase biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0008245 lysosomal membrane hydrogen-transporting ATPase|V-ATPase OBSOLETE. (Was not defined before being made obsolete). GO:0008244 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008244 GO:0008243 obsolete plasminogen activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008243 abbokinase activity|urinary esterase A|tissue plasminogen activator activity|urokinase activity|plasminogen activator activity|urinary plasminogen activator activity|t-plasminogen activator activity|u-plasminogen activator activity|cellular plasminogen activator activity|tPA activity|plasminogen activator, tissue-type|tissue-type plasminogen activator activity|urokinase plasminogen activator|urokinase-type plasminogen activator|two-chain urokinase-type plasminogen activator|t-PA|u-PA|double-chain urokinase-type plasminogen activator|uPA OBSOLETE. Catalysis of the specific cleavage of an Arg-Val bond in plasminogen to form plasmin. GO:0008242 omega peptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008242 MetaCyc:3.4.19.9-RXN|EC:3.4.19.-|EC:3.4.19.9|MetaCyc:PEPTIDYL-GLYCINAMIDASE-RXN|EC:3.4.19.2 peptidase activity, acting on peptides containing modified amino acids Catalysis of the cleavage of non-standard peptide bonds releasing substituted amino acids such as pyroglutamate or cleave isopeptide bonds, such as many deubiquitinating enzymes. GO:0008241 peptidyl-dipeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008241 EC:3.4.15.- Catalysis of the release of C-terminal dipeptides from a polypeptide chain. GO:0008251 tRNA-specific adenosine deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008251 Reactome:R-HSA-6782336|Reactome:R-HSA-6782311 tRNA-adenosine deaminase activity Catalysis of the reaction: adenosine + H2O = inosine + NH3, in a tRNA molecule. GO:0008250 oligosaccharyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0008250 oligosaccharyl transferase complex|OST complex A protein complex that is found in the endoplasmic reticulum membrane of eukaryotes and transfers lipid-linked oligosaccharide precursor to asparagine residues on nascent proteins. In yeast, the complex includes at least nine different subunits, whereas in mammalian cells at least three different forms of the complex have been detected. GO:0033204 ribonuclease P RNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033204 RNase P RNA binding Interacting selectively and non-covalently with the RNA subunit of ribonuclease P. GO:0033203 DNA helicase A complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033203 A homohexameric protein complex that possesses DNA helicase activity; associates with DNA polymerase alpha-primase and translocates in the 5' to 3' direction. GO:0033202 DNA helicase complex biolink:CellularComponent go-plus goslim_pir|goslim_metagenomics http://purl.obolibrary.org/obo/GO_0033202 A protein complex that possesses DNA helicase activity. GO:0033201 alpha-1,4-glucan synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033201 RHEA:18189|EC:2.4.1.21 1,4-alpha-glucan synthase activity Catalysis of the reaction: RDP-glucose + [alpha-D-glucosyl-(1,4)]n = RDP + [alpha-D-glucosyl-(1,4)]n+1, where RDP is ADP or UDP. GO:0033200 inositol heptakisphosphate 5-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033200 IP7 5-kinase activity|diphosphoinositol-pentakisphosphate 5-kinase activity Catalysis of the reaction: ATP + 4-diphospho-1D-myo-inositol (1,2,3,5,6)pentakisphosphate = 4,5-bisdiphosphoinositol-1D-myoinositol (1,2,3,6)tetrakisphosphate, and ATP + 6-diphospho-1D-myo-inositol (1,2,3,4,5)pentakisphosphate = 5,6-bisdiphosphoinositol-1D-myoinositol (1,2,3,4)tetrakisphosphate. GO:0008259 obsolete transforming growth factor beta ligand binding to type I receptor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008259 TGF-beta ligand binding to type I receptor|TGFbeta ligand binding to type I receptor|transforming growth factor beta ligand binding to type I receptor OBSOLETE. (Was not defined before being made obsolete). GO:0008258 head involution biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008258 Movement of the anterior ectoderm to the interior of the embryo. GO:0008257 protein histidine tele-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008257 MetaCyc:2.7.13.2-RXN|EC:2.7.13.2|RHEA:11860 protein-histidine tele-kinase activity|HK3|ATP:protein-L-histidine N-tele-phosphotransferase activity|ATP:protein-L-histidine Ntau-phosphotransferase activity Catalysis of the reaction: ATP + protein L-histidine = ADP + protein N(tau)-phospho-L-histidine. GO:0008256 protein histidine pros-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008256 MetaCyc:2.7.13.1-RXN|EC:2.7.13.1|RHEA:22720 HK2|protein-histidine pros-kinase activity|ATP:protein-L-histidine N-pros-phosphotransferase activity|ATP:protein-L-histidine Npi-phosphotransferase activity Catalysis of the reaction: ATP + protein L-histidine = ADP + protein N(pi)-phospho-L-histidine. GO:0008255 ecdysis-triggering hormone activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008255 The action characteristic of ecdysis-triggering hormone, a peptide hormone that, upon receptor binding, initiates pre-ecdysis and ecdysis (i.e. cuticle shedding) through direct action on the central nervous system. GO:0008254 3'-nucleotidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008254 EC:3.1.3.6|MetaCyc:3-NUCLEOTID-RXN|RHEA:10144 3'-ribonucleotide phosphohydrolase activity|3' nucleotidase activity|3'-phosphatase activity|3'-mononucleotidase activity|3'-ribonucleotidase activity Catalysis of the reaction: a 3'-ribonucleotide + H2O = a ribonucleoside + phosphate. CHEBI:104120 alpha-methylene gamma-butyrolactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_104120 GO:0008253 5'-nucleotidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008253 RHEA:12484|MetaCyc:5-NUCLEOTID-RXN|EC:3.1.3.5|Reactome:R-HSA-109291|Reactome:R-HSA-109278|Reactome:R-HSA-109514|Reactome:R-HSA-109387|Reactome:R-HSA-109480|Reactome:R-HSA-109449|Reactome:R-HSA-8940074|Reactome:R-HSA-109470|Reactome:R-HSA-74248|Reactome:R-HSA-5694126|Reactome:R-HSA-109415|Reactome:R-HSA-8940070|Reactome:R-HSA-109380 AMP phosphohydrolase|5'-ribonucleotide phosphohydrolase activity|snake venom 5'-nucleotidase|thimidine monophosphate nucleotidase|5'-AMP nucleotidase|5' nucleotidase activity|AMP phosphatase|AMPase|5'-AMPase|5'-mononucleotidase activity|adenosine 5'-phosphatase|uridine 5'-nucleotidase|5'-adenylic phosphatase|UMPase|adenosine monophosphatase Catalysis of the reaction: a 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. GO:0008252 nucleotidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008252 RHEA:22140|EC:3.1.3.31|MetaCyc:NUCLEOTIDASE-RXN nucleotide phosphohydrolase activity|deoxyinosine-activated nucleotidase (DIAN)|deoxyribonucleoside-activated nucleotidase (DAN)|NSP II|NSP I|nucleotide-specific phosphatase activity|acid nucleotidase activity Catalysis of the reaction: a nucleotide + H2O = a nucleoside + phosphate. GO:0008262 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008262 GO:0008261 allatostatin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008261 Combining with allatostatin to initiate a change in cell activity. GO:0008260 3-oxoacid CoA-transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008260 EC:2.8.3.5|Reactome:R-HSA-74177|RHEA:25480|MetaCyc:3-OXOACID-COA-TRANSFERASE-RXN 3-oxo-CoA transferase activity|3-ketoacid CoA-transferase activity|3-oxoacid coenzyme A-transferase activity|succinyl coenzyme A-acetoacetyl coenzyme A-transferase activity|acetoacetyl coenzyme A-succinic thiophorase activity|succinyl-CoA:3-oxo-acid CoA-transferase activity|acetoacetate succinyl-CoA transferase activity|3-ketoacid coenzyme A transferase activity|succinyl-CoA transferase activity|3-oxoacid CoA dehydrogenase activity|succinyl-CoA:3-ketoacid-CoA transferase activity Catalysis of the reaction: succinyl-CoA + a 3-oxo acid = succinate + a 3-oxo-acyl-CoA. GO:0008229 obsolete opsonin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008229 opsonin activity OBSOLETE. Binds to microorganisms or other particulate material (for example, foreign erythrocytes) to increase the susceptibility of the latter to phagocytosis. GO:0008228 opsonization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008228 Wikipedia:Opsonin The process in which a microorganism (or other particulate material) is rendered more susceptible to phagocytosis by coating with an opsonin, a blood serum protein such as a complement component or antibody. GO:0008227 G protein-coupled amine receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008227 amine receptor activity, G-protein coupled|biogenic amine receptor|G-protein coupled amine receptor activity Combining with an extracellular amine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. GO:0008226 tyramine receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008226 Combining with the biogenic amine tyramine to initiate a change in cell activity. Tyramine is a sympathomimetic amine derived from tyrosine with an action resembling that of epinephrine. CHEBI:48470 amidobenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48470 GO:0008225 obsolete Gram-negative antibacterial peptide activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008225 Gram-negative antibacterial peptide activity OBSOLETE. Inhibits the growth of, or directly kills, Gram-negative bacterial cells. GO:0008224 obsolete Gram-positive antibacterial peptide activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008224 Gram-positive antibacterial peptide activity OBSOLETE. Inhibits the growth of, or directly kills, Gram-positive bacterial cells. GO:0008223 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008223 GO:0008222 obsolete tumor antigen biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008222 tumor antigen OBSOLETE. (Was not defined before being made obsolete). CHEBI:48474 (25R)-3alpha,7alpha-dihydroxy-5beta-cholestan-26-oyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48474 GO:0008221 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008221 GO:0008220 obsolete necrosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008220 necrosis OBSOLETE. The processes that cause necrosis, the death of tissues, in another organism. CHEBI:48467 (25R)-3alpha,7alpha-dihydroxy-5beta-cholestan-26-oic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48467 CHEBI:48469 pyrimidinimine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48469 GO:0008239 dipeptidyl-peptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008239 MetaCyc:3.4.14.11-RXN|EC:3.4.14.11|EC:3.4.14.5|EC:3.4.14.4|EC:3.4.14.2|EC:3.4.14.1|MetaCyc:3.4.14.4-RXN Catalysis of the hydrolysis of N-terminal dipeptides from a polypeptide chain. GO:0008238 exopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008238 exoprotease activity Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain, in a reaction that requires a free N-terminal amino group, C-terminal carboxyl group or both. GO:0008237 metallopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008237 Reactome:R-HSA-9013284|Reactome:R-HSA-193679|Reactome:R-HSA-2220944|Reactome:R-HSA-157629|Reactome:R-HSA-9604264|Reactome:R-HSA-2220976|Reactome:R-HSA-2022396|Reactome:R-HSA-157632|Reactome:R-HSA-5211405|Reactome:R-HSA-8986181|Reactome:R-HSA-2730752|Reactome:R-HSA-3928660|Reactome:R-HSA-2666278|Reactome:R-HSA-9662837|Reactome:R-HSA-5211387|Reactome:R-HSA-2022399|Reactome:R-HSA-2022393|Reactome:R-HSA-5211400|Reactome:R-HSA-5211356|Reactome:R-HSA-2022368|Reactome:R-HSA-5211391|Reactome:R-HSA-5211340 metalloproteinase activity|metalloprotease activity Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. GO:0047801 L-cysteine:2-oxoglutarate aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047801 MetaCyc:CYSTEINE-AMINOTRANSFERASE-RXN|EC:2.6.1.3|Reactome:R-HSA-9012597|RHEA:17441 L-cysteine aminotransferase activity|CGT|cysteine aminotransferase activity|cysteine transaminase activity Catalysis of the reaction: L-cysteine + 2-oxoglutarate = mercaptopyruvate + L-glutamate. GO:0047800 cysteamine dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047800 MetaCyc:CYSTEAMINE-DIOXYGENASE-RXN|RHEA:14409|KEGG_REACTION:R02467|EC:1.13.11.19|Reactome:R-HSA-6814153 persulfurase activity|cysteamine:oxygen oxidoreductase activity|2-aminoethanethiol:oxygen oxidoreductase activity|cysteamine oxygenase activity Catalysis of the reaction: cysteamine + O(2) = H(+) + hypotaurine. GO:0008236 serine-type peptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008236 Reactome:R-HSA-6801766|Reactome:R-HSA-1461993|Reactome:R-HSA-2022383|Reactome:R-HSA-3132753 serine protease activity Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine). GO:0008235 metalloexopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008235 Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. GO:0008234 cysteine-type peptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008234 Reactome:R-HSA-5660752|Reactome:R-HSA-2467775|Reactome:R-HSA-2022381|Reactome:R-HSA-2467809 thiol protease activity|cysteine protease activity Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile. GO:0008233 peptidase activity biolink:MolecularActivity go-plus goslim_pir|goslim_drosophila|goslim_aspergillus|goslim_metagenomics|goslim_generic|goslim_chembl|goslim_yeast|goslim_candida http://purl.obolibrary.org/obo/GO_0008233 Reactome:R-HSA-3065959|Reactome:R-HSA-6803060|Reactome:R-HSA-5685902|Reactome:R-HSA-376149|Reactome:R-HSA-5684864|Reactome:R-HSA-3139027|Reactome:R-HSA-4167501|EC:3.4.-.-|Reactome:R-HSA-5655483|Reactome:R-HSA-5693319|Reactome:R-HSA-3000243|Reactome:R-HSA-448678|Reactome:R-HSA-205112|Reactome:R-HSA-3065958 peptidase activity, acting on D-amino acid peptides|peptide hydrolase activity|hydrolase, acting on peptide bonds|proteinase activity|protease activity|peptidase activity, acting on L-amino acid peptides Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid. CHEBI:2807 arbutin 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_2807 GO:0008232 activator ecdysone receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0008232 activator ecdysone receptor holocomplex A protein complex consisting of a heterodimer of Ecdysone receptor (EcR) and ultraspiracle (usp) bound to the ligand ecdysone, which activates transcription of target genes. CHEBI:48462 5-deoxy-alpha-D-ribose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48462 GO:0008231 repressor ecdysone receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0008231 repressor ecdysone receptor holocomplex A protein complex consisting of a heterodimer of Ecdysone receptor (EcR) and ultraspiracle (usp) plus an associated corepressor such as SMRTER, which represses transcription of target genes. GO:0008230 ecdysone receptor holocomplex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0008230 A heterodimeric complex containing the products of the insect genes Ecdysone receptor (EcR) and ultraspiracle (usp). Binding of ecdysone promotes association between the two subunits, and the receptor complex then initiates molting and metamorphosis by binding DNA and regulating the transcription of target genes. GO:0047809 D-2-hydroxy-acid dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047809 EC:1.1.99.6|MetaCyc:D-2-HYDROXY-ACID-DEHYDROGENASE-RXN|KEGG_REACTION:R00297|RHEA:15089 (R)-2-hydroxy-acid:(acceptor) 2-oxidoreductase activity|2-hydroxy acid dehydrogenase activity Catalysis of the reaction: (R)-lactate + A = AH(2) + pyruvate. GO:0008240 tripeptidyl-peptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008240 MetaCyc:3.4.14.9-RXN|EC:3.4.14.9|MetaCyc:3.4.14.10-RXN|EC:3.4.14.10 Catalysis of the release of an N-terminal tripeptide from a polypeptide. GO:0047808 D(-)-tartrate dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047808 MetaCyc:D--TARTRATE-DEHYDRATASE-RXN|KEGG_REACTION:R00340|EC:4.2.1.81|RHEA:18289 D-tartrate dehydratase activity|(S,S)-tartrate hydro-lyase activity|(S,S)-tartrate hydro-lyase (oxaloacetate-forming) Catalysis of the reaction: D-tartrate = H(2)O + oxaloacetate. GO:0047807 cytokinin 7-beta-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047807 MetaCyc:CYTOKININ-7-BETA-GLUCOSYLTRANSFERASE-RXN|EC:2.4.1.118|RHEA:23272|KEGG_REACTION:R04071 UDP-glucose-zeatin 7-glucosyltransferase activity|UDPglucose:zeatin 7-glucosyltransferase activity|UDP-glucose:zeatin 7-glucosyltransferase activity|cytokinin 7-b-glucosyltransferase activity|uridine diphosphoglucose-zeatin 7-glucosyltransferase activity|cytokinin 7-glucosyltransferase activity Catalysis of the reaction: 6-alkylaminopurine + UDP-D-glucose = 6-alkylamino-7-beta-D-glucosylpurine + H+ + UDP. This reaction is an N-glucosylation event. GO:0047806 cytochrome-c3 hydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047806 RHEA:20625|UM-BBD_enzymeID:e0481|EC:1.12.2.1|MetaCyc:CYTOCHROME-C3-HYDROGENASE-RXN cytochrome c3 reductase activity|cytochrome hydrogenase activity|H2:ferricytochrome c3 oxidoreductase activity|hydrogen:ferricytochrome-c3 oxidoreductase activity|H(2):ferricytochrome c3 oxidoreductase activity Catalysis of the reaction: 2 H2 + ferricytochrome c3 = 4 H+ + ferrocytochrome c3. GO:0047805 cytidylate cyclase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047805 MetaCyc:CYTIDYLATE-CYCLASE-RXN|RHEA:14737|KEGG_REACTION:R00574|EC:4.6.1.6 cytidylyl cyclase activity|3'5'-cyclic-CMP synthase activity|CTP diphosphate-lyase (cyclizing)|cytidyl cyclase activity|3',5'-cyclic-CMP synthase activity|CTP diphosphate-lyase (cyclizing; 3',5'-cyclic-CMP-forming) Catalysis of the reaction: CTP = 3',5'-cyclic CMP + diphosphate + H(+). GO:0047804 cysteine-S-conjugate beta-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047804 MetaCyc:CYSTEINE-S-CONJUGATE-BETA-LYASE-RXN|EC:4.4.1.13|RHEA:18121 cysteine-S-conjugate b-lyase activity|cysteine conjugate beta-lyase activity|L-cysteine-S-conjugate thiol-lyase (deaminating) activity|glutamine transaminase K/cysteine conjugate beta-lyase activity|L-cysteine-S-conjugate thiol-lyase (deaminating; pyruvate-forming) Catalysis of the reaction: RS-CH2-CH(NH3+)COO- = RSH + NH3 + pyruvate. GO:0047803 cysteine lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047803 RHEA:20916|MetaCyc:CYSTEINE-LYASE-RXN|EC:4.4.1.10 L-cysteine hydrogen-sulfide-lyase (adding sulfite)|cysteine (sulfite) lyase activity|L-cysteine hydrogen-sulfide-lyase (adding sulfite; L-cysteate-forming) Catalysis of the reaction: L-cysteine + sulfite = L-cysteate + sulfide. GO:0047802 cysteine-conjugate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047802 MetaCyc:CYSTEINE-CONJUGATE-TRANSAMINASE-RXN|KEGG_REACTION:R04338|EC:2.6.1.75|RHEA:13485 cysteine-conjugate alpha-ketoglutarate transaminase (CAT-1)|cysteine conjugate aminotransferase activity|S-(4-bromophenyl)-L-cysteine:2-oxoglutarate aminotransferase activity Catalysis of the reaction: 2-oxoglutarate + S-(4-bromophenyl)-L-cysteine = (4-bromophenylsulfanyl)pyruvate + L-glutamate. OBA:1000078 attribute of organelle biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_1000078 organelle quality trait|quality of organelle The quality of a organelle. GO:0033196 tryparedoxin peroxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033196 MetaCyc:1.11.1.15-RXN TXNPx activity Catalysis of the reaction: tryparedoxin + hydrogen peroxide = tryparedoxin disulfide + H2O. GO:0033195 response to alkyl hydroperoxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033195 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkyl hydroperoxide stimulus. Alkyl hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH, where the substituent is an alkyl group. GO:0033194 response to hydroperoxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033194 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroperoxide stimulus. Hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH. GO:0033193 Lsd1/2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033193 SAPHIRE complex|Swm complex|Swm1/2 complex A nucleosome-binding protein complex that comprises two SWIRM domain histone demethylases and two PHD finger proteins. The complex is involved in transcriptional regulation via heterochromatic silencing and the regulation of chromatin boundary formation, and was first identified in fission yeast. GO:0033192 calmodulin-dependent protein phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033192 Reactome:R-HSA-2730849|Reactome:R-HSA-4551451 calcineurin activity|calcium/calmodulin-dependent protein phosphatase activity|calcium- and calmodulin-dependent protein phosphatase activity|Ca2+/CaM-dependent protein phosphatase activity Catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate, dependent on the presence of calcium-bound calmodulin. GO:0033191 macrophomate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033191 Catalysis of the reaction: a 2-pyrone + oxalacetate = macrophomate. GO:0033190 solanapyrone synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033190 Catalysis of the cyclization of double bonds in prosolanapyrone II to form (-)-solanapyrone A. OBA:1000076 attribute of cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_1000076 cell quality trait|quality of cell The quality of a cell. GO:0033199 obsolete inositol heptakisphosphate 4-kinase or 6-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033199 inositol heptakisphosphate 4-kinase or 6-kinase activity OBSOLETE. Catalysis of the reaction: ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = 4,5-bisdiphosphoinositol-1D-myoinositol (1,2,3,6)tetrakisphosphate, and ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = 5,6-bisdiphosphoinositol-1D-myoinositol (1,2,3,4)tetrakisphosphate. GO:0033198 response to ATP biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033198 response to adenosine triphosphate|response to adenosine 5'-triphosphate Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus. GO:0033197 response to vitamin E biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033197 response to O-Acetyl-alpha-tocopherol|response to DL-alpha-tocopherol acetate|response to DL-alpha-tocopheryl acetate Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin E stimulus. GO:0033185 dolichol-phosphate-mannose synthase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033185 dolichyl-phosphate beta-D-mannosyltransferase complex|DPM synthase complex A protein complex that possesses dolichyl-phosphate beta-D-mannosyltransferase activity; contains a catalytic subunit, a regulatory subunit, and a third subunit that stabilizes the complex. In human and several other metazoa, the subunits are named DPM1, DPM2 and DPM3, respectively. GO:0033184 positive regulation of histone ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033184 Any process that activates or increases the frequency, rate or extent of the addition of a ubiquitin group to a histone protein. GO:0033183 negative regulation of histone ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033183 Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of a ubiquitin group to a histone protein. GO:0033182 regulation of histone ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033182 Any process that modulates the frequency, rate or extent of the addition of a ubiquitin group to a histone protein. GO:0033181 plasma membrane proton-transporting V-type ATPase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033181 plasma membrane hydrogen ion-transporting ATPase A proton-transporting two-sector ATPase complex found in the plasma membrane. GO:0033180 proton-transporting V-type ATPase, V1 domain biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033180 A protein complex that forms part of a proton-transporting V-type ATPase and catalyzes ATP hydrolysis. The V1 complex consists of: (1) a globular headpiece with three alternating copies of subunits A and B that form a ring, (2) a central rotational stalk composed of single copies of subunits D and F, and (3) a peripheral stalk made of subunits C, E, G and H. Subunits A and B mediate the hydrolysis of ATP at three reaction sites associated with subunit A. GO:0033189 response to vitamin A biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033189 response to retinol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin A stimulus. GO:0033188 sphingomyelin synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033188 MetaCyc:2.7.8.27-RXN|KEGG_REACTION:R08969|Reactome:R-HSA-429798|Reactome:R-HSA-429786|EC:2.7.8.27|RHEA:18765 SMS2|SMS1|SM synthase activity|ceramide:phosphatidylcholine cholinephosphotransferase activity|phosphatidylcholine:ceramide cholinephosphotransferase activity Catalysis of the reaction: 1,2-diacyl-sn-glycero-3-phosphocholine + ceramide = 1,2-diacyl-sn-glycerol + sphingomyelin. GO:0033187 obsolete inositol hexakisphosphate 4-kinase or 6-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033187 inositol hexakisphosphate 4-kinase or 6-kinase activity OBSOLETE. Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 4-diphospho-1D-myo-inositol (1,2,3,5,6)pentakisphosphate, and ATP + 1D-myo-inositol hexakisphosphate = ADP + 6-diphospho-1D-myo-inositol (1,2,3,4,5)pentakisphosphate. GO:0033186 CAF-1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033186 chromatin assembly factor 1 complex A conserved heterotrimeric protein complex that promotes histone H3 and H4 deposition onto newly synthesized DNA during replication or DNA repair; specifically facilitates replication-dependent nucleosome assembly with the major histone H3 (H3.1). In many species the CAF-1 subunits are designated p150, p60, and p48. GO:0033174 chloroplast proton-transporting ATP synthase complex, catalytic core CF(1) biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033174 chloroplast proton-transporting F-type ATPase complex, catalytic core CF(1) The catalytic sector of the mitochondrial hydrogen-transporting ATP synthase; it comprises the catalytic core and central stalk, and is peripherally associated with the chloroplast thylakoid membrane when the entire ATP synthase is assembled. The chloroplast F0 domain contains three alpha, three beta, one gamma, one delta, and one epsilon subunits. GO:0033173 calcineurin-NFAT signaling cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033173 calcineurin-NFAT signaling pathway|calcineurin-NFAT signalling pathway Any intracellular signal transduction in which the signal is passed on within the cell by activation of a member of the NFAT protein family as a consequence of NFAT dephosphorylation by Ca(2+)-activated calcineurin. The cascade begins with calcium-dependent activation of the phosphatase calcineurin. Calcineurin dephosphorylates multiple phosphoserine residues on NFAT, resulting in the translocation of NFAT to the nucleus. The cascade ends with regulation of transcription by NFAT. The calcineurin-NFAT cascade lies downstream of many cell surface receptors, including G protein-coupled receptors (GPCRs) and receptor tyrosine kinases (RTKs) that signal to mobilize calcium ions (Ca2+). GO:0033172 gas vesicle shell biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033172 gas vesicle membrane|gas vesicle wall The proteinaceous structure surrounding a gas vesicle. GO:0033171 obsolete nucleoprotein filament-forming ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033171 nucleoprotein filament-forming ATPase activity OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate to drive the assembly of proteins such as Rad51p onto single-stranded (ss) DNA to form a helical nucleoprotein filament. GO:0033170 protein-DNA loading ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033170 DNA-protein loading ATPase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the assembly of a protein or protein complex onto a DNA molecule. GO:0033179 proton-transporting V-type ATPase, V0 domain biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033179 A protein complex that forms part of a proton-transporting V-type ATPase and mediates proton transport across a membrane. The V0 complex consists of at least four different subunits (a,c,d and e); six or more c subunits form a proton-binding rotor ring. GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033178 A protein complex that forms part of a proton-transporting two-sector ATPase complex and catalyzes ATP hydrolysis or synthesis. The catalytic domain (F1, V1, or A1) comprises a hexameric catalytic core and a central stalk, and is peripherally associated with the membrane when the two-sector ATPase is assembled. GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033177 A protein complex that forms part of a proton-transporting two-sector ATPase complex and carries out proton transport across a membrane. The proton-transporting domain (F0, V0, or A0) includes integral and peripheral membrane proteins. GO:0033176 proton-transporting V-type ATPase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033176 hydrogen-translocating V-type ATPase complex A proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient. The resulting transmembrane electrochemical potential of H+ is used to drive a variety of (i) secondary active transport systems via H+-dependent symporters and antiporters and (ii) channel-mediated transport systems. The complex comprises a membrane sector (V0) that carries out proton transport and a cytoplasmic compartment sector (V1) that catalyzes ATP hydrolysis. V-type ATPases are found in the membranes of organelles such as vacuoles, endosomes, and lysosomes, and in the plasma membrane. GO:0033175 chloroplast proton-transporting ATP synthase complex, coupling factor CF(o) biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033175 chloroplast proton-transporting ATP synthase complex, coupling factor CF(0)|chloroplast proton-transporting F-type ATPase complex, coupling factor CF(o) All non-F1 subunits of the chloroplast hydrogen-transporting ATP synthase, including integral and peripheral chloroplast thylakoid membrane proteins. GO:0033163 microneme membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033163 The lipid bilayer surrounding a microneme. GO:0033162 melanosome membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033162 The lipid bilayer surrounding a melanosome. GO:0033161 mitogen-activated protein kinase kinase kinase kinase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033161 MAPKKKK binding Interacting selectively and non-covalently with a mitogen-activated protein kinase kinase kinase kinase, any protein that can phosphorylate a MAP kinase kinase kinase. GO:0033160 obsolete positive regulation of protein import into nucleus, translocation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033160 positive regulation of protein import into cell nucleus, translocation OBSOLETE. Any process that activates or increases the vectorial transfer of a protein from the cytoplasm into the nucleus, across the nuclear membrane. GO:0033169 histone H3-K9 demethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033169 The modification of histone H3 by the removal of a methyl group from lysine at position 9 of the histone. GO:0033168 conversion of ds siRNA to ss siRNA involved in RNA interference biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033168 RNA interference, conversion of ds siRNA to ss siRNA The process in which double-stranded siRNA molecules are converted to single-stranded siRNAs; required for the formation of a mature RITS complex during RNA interference. GO:0033167 ARC complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033167 argonaute siRNA chaperone complex A ribonucleoprotein complex that contains members of the Argonaute family of proteins, additional protein subunits, and duplex siRNA; required for heterochromatin assembly and siRNA generation. Possibly involved in the conversion of ds siRNA to ss siRNA. GO:0033166 hyaline layer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033166 A multilayered extraembryonic matrix that functions as a substrate for cell adhesion through early development. It is thought to protect and lubricate the embryo, stabilize the blastomeres during morphogenesis, and regulate nutrient intake. The major constituent of the hyaline layer is the protein hyalin. This matrix has been found in echinoderms. GO:0033165 interphotoreceptor matrix biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033165 A specialized extracellularc matrix that surrounds the photoreceptors of the retina and lies between them and the apical surface of the retinal pigment epithelium. The IPM has been implicated in several important activities required for photoreceptor function and maintenance. GO:0033164 glycolipid 1,6-alpha-mannosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033164 EC:2.4.1.232|MetaCyc:2.4.1.232-RXN GDP-mannose:oligosaccharide 6-alpha-D-mannosyltransferase activity|GDP-mannose:oligosaccharide 1,6-alpha-D-mannosyltransferase activity|initiation-specific alpha-1,6-mannosyltransferase activity|GDP-mannose:glycolipid 1,6-alpha-D-mannosyltransferase activity|glycolipid 6-alpha-mannosyltransferase activity Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->6)-D-mannosyl-D-mannose linkage. GO:0033152 immunoglobulin V(D)J recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033152 immunoglobulin V-D-J joining|immunoglobulin V-J recombination|immunoglobulin V-J joining|immunoglobulin V(D)J joining|immunoglobulin V-D-J recombination The process in which immunoglobulin gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin heavy chains V, D, and J gene segments are joined, and for immunoglobulin light chains V and J gene segments are joined. GO:0033151 V(D)J recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033151 Wikipedia:V(D)J_recombination V-J recombination|V-J joining|V(D)J joining|V-D-J recombination|V-D-J joining The process in which immune receptor V, D, and J, or V and J gene segments, depending on the specific receptor, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). GO:0033150 cytoskeletal calyx biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033150 A large cytoskeletal structure located at the posterior end of the perinuclear theca of a mammalian sperm head. The nucleus is tightly associated with the calyx, which contains calicin and basic cylicin proteins. GO:0033159 obsolete negative regulation of protein import into nucleus, translocation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033159 negative regulation of protein import into cell nucleus, translocation OBSOLETE. Any process that stops, prevents or reduces the vectorial transfer of a protein from the cytoplasm into the nucleus, across the nuclear membrane. GO:0033158 obsolete regulation of protein import into nucleus, translocation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033158 regulation of protein import into cell nucleus, translocation OBSOLETE. Any process that modulates the vectorial transfer of a protein from the cytoplasm into the nucleus, across the nuclear membrane. GO:0033157 regulation of intracellular protein transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033157 Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells. GO:0033156 oligogalacturonide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033156 The directed movement of oligogalacturonides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0033155 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0033155 GO:0033154 ABC-type oligogalacturonide transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033154 TC:3.A.1.1.11 oligogalacturonide transporting ATPase activity|ATP-dependent oligogalacturonide transmembrane transporter activity|ATPase-coupled oligogalacturonide transmembrane transporter activity|oligogalacturonide transmembrane transporter activity|oligogalacturonide-transporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + oligogalacturonide(out) = ADP + phosphate + oligogalacturonide(in). GO:0033153 T cell receptor V(D)J recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033153 T cell receptor V-J recombination|T cell receptor V-J joining|T cell receptor V-D-J recombination|T cell receptor V(D)J joining|T cell receptor V-D-J joining|TCR V(D)J recombination|T-cell receptor V(D)J recombination The process in which T cell receptor V, D, and J, or V and J gene segments, depending on the specific locus, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). GO:0008189 obsolete apoptosis inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008189 apoptosis inhibitor activity OBSOLETE. The function held by products which directly block any step in the process of apoptosis. GO:0008188 neuropeptide receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008188 Combining with a neuropeptide to initiate a change in cell activity. GO:0008187 poly-pyrimidine tract binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008187 Interacting selectively and non-covalently with any stretch of pyrimidines (cytosine or uracil) in an RNA molecule. GO:0008186 RNA-dependent ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008186 RNA-dependent adenosinetriphosphatase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of RNA, and it drives another reaction. GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033141 activation of serine phosphorylation of STAT3 protein|up-regulation of serine phosphorylation of STAT3 protein|positive regulation of serine phosphorylation of STAT3 protein|upregulation of serine phosphorylation of STAT3 protein|up regulation of serine phosphorylation of STAT3 protein Any process that activates or increases the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein. GO:0008196 vitellogenin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008196 Receiving vitellogenin, and delivering vitellogenin into the cell via endocytosis. GO:0008195 phosphatidate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008195 Reactome:R-HSA-1483203|Reactome:R-HSA-6797630|Reactome:R-HSA-5221130|EC:3.1.3.4|Reactome:R-HSA-163750|Reactome:R-HSA-163688|Reactome:R-HSA-164056|Reactome:R-HSA-163689|Reactome:R-HSA-2029468|MetaCyc:PHOSPHATIDATE-PHOSPHATASE-RXN|Reactome:R-HSA-75899|Reactome:R-HSA-390329|RHEA:27429 phosphatidic acid phosphatase activity|phosphatidate phosphohydrolase activity|phosphatic acid phosphohydrolase activity|acid phosphatidyl phosphatase activity|3-sn-phosphatidate phosphohydrolase activity|phosphatic acid phosphatase activity Catalysis of the reaction: a 1,2-diacylglycerol 3-phosphate + H2O = a 1,2-diacyl-sn-glycerol + phosphate. GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033140 down-regulation of serine phosphorylation of STAT3 protein|inhibition of serine phosphorylation of STAT3 protein|negative regulation of serine phosphorylation of STAT3 protein|down regulation of serine phosphorylation of STAT3 protein|downregulation of serine phosphorylation of STAT3 protein Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein. GO:0008194 UDP-glycosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008194 Reactome:R-HSA-162730 Catalysis of the transfer of a glycosyl group from a UDP-sugar to a small hydrophobic molecule. GO:0008193 tRNA guanylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008193 EC:2.7.7.79|RHEA:54564 Catalysis of the posttranscriptional addition of a guanyl residue to the 5' end of a tRNA molecule; observed for His tRNAs. GO:0008192 RNA guanylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008192 Catalysis of the posttranscriptional addition of a guanyl residue to the 5' end of an RNA molecule. CARO:0030000 biological entity biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/CARO_0030000 GO:0008191 metalloendopeptidase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008191 metalloproteinase inhibitor|metalloprotease inhibitor Stops, prevents or reduces the activity of metalloendopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain and contain a chelated metal ion at their active sites which is essential to their catalytic activity. GO:0008190 eukaryotic initiation factor 4E binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008190 eIF4E binding Interacting selectively and non-covalently with eukaryotic initiation factor 4E, a polypeptide factor involved in the initiation of ribosome-mediated translation. GO:0033149 FFAT motif binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033149 Interacting selectively and non-covalently with the FFAT motif, a short motif containing diphenylalanine in an acidic tract that targets proteins to the cytosolic surface of the ER and to the nuclear membrane by binding directly to members of the VAP (VAMP-associated protein) protein family. GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033148 positive regulation of estrogen receptor signalling pathway|positive regulation of estrogen receptor signaling pathway Any process that activates or increases the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway. GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033147 negative regulation of estrogen receptor signaling pathway|negative regulation of estrogen receptor signalling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway. GO:0033146 regulation of intracellular estrogen receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033146 regulation of estrogen receptor signalling pathway|regulation of estrogen receptor signaling pathway Any process that modulates the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway. GO:0033145 positive regulation of intracellular steroid hormone receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033145 positive regulation of steroid hormone receptor signalling pathway|positive regulation of steroid hormone receptor signaling pathway Any process that activates or increases the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway. GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033144 negative regulation of steroid hormone receptor signaling pathway|negative regulation of steroid hormone receptor signalling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway. GO:0033143 regulation of intracellular steroid hormone receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033143 regulation of steroid hormone receptor signaling pathway|regulation of steroid hormone receptor signalling pathway Any process that modulates the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway. GO:0033142 progesterone receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033142 Interacting selectively and non-covalently with a progesterone receptor. OBA:1000099 appendage trait biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_1000099 quality of appendage|appendage quality trait The quality of a appendage. GO:0033139 regulation of peptidyl-serine phosphorylation of STAT protein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033139 regulation of serine phosphorylation of STAT3 protein Any process that modulates the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein. GO:0008199 ferric iron binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008199 Interacting selectively and non-covalently with ferric iron, Fe(III). GO:0008198 ferrous iron binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008198 Interacting selectively and non-covalently with ferrous iron, Fe(II). GO:0008197 obsolete yolk protein biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008197 yolk protein OBSOLETE. (Was not defined before being made obsolete). GO:0033130 acetylcholine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033130 Interacting selectively and non-covalently with an acetylcholine receptor. OBA:1000090 membrane quality biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_1000090 membrane quality trait|quality of membrane The quality of a membrane. GO:0033138 positive regulation of peptidyl-serine phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033138 Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-serine. GO:0033137 negative regulation of peptidyl-serine phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033137 Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-serine. GO:0033136 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0033136 OBA:1000091 membrane morphology biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_1000091 morphology of membrane|membrane morphology trait The morphology of a membrane. GO:0033135 regulation of peptidyl-serine phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033135 Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-serine. GO:0033134 ubiquitin activating enzyme binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033134 Interacting selectively and non-covalently with a ubiquitin activating enzyme, any of the E1 proteins. GO:0033133 positive regulation of glucokinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033133 glucokinase activator|stimulation of glucokinase activity|up-regulation of glucokinase activity|up regulation of glucokinase activity|upregulation of glucokinase activity Any process that activates or increases the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule. GO:0033132 negative regulation of glucokinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033132 glucokinase inhibitor|down-regulation of glucokinase activity|downregulation of glucokinase activity|down regulation of glucokinase activity|inhibition of glucokinase activity Any process that stops, prevents, or reduces the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule. GO:0033131 regulation of glucokinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033131 glucokinase regulator Any process that modulates the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule. GO:0047771 carboxymethylhydantoinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047771 EC:3.5.2.4|KEGG_REACTION:R02284|MetaCyc:CARBOXYMETHYLHYDANTOINASE-RXN|RHEA:12028 hydantoin hydrolase activity|L-5-carboxymethylhydantoin amidohydrolase activity Catalysis of the reaction: L-5-carboxymethylhydantoin + H(2)O = N-carbamoyl-L-aspartate + H(+). CHEBI:24401 glycosinolate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24401 GO:0047770 carboxylate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047770 MetaCyc:CARBOXYLATE-REDUCTASE-RXN|EC:1.2.99.6 carboxylic acid reductase activity|aldehyde:(acceptor) oxidoreductase activity|aldehyde:acceptor oxidoreductase activity Catalysis of the reaction: an aldehyde + acceptor + H2O = a carboxylate + reduced acceptor. CHEBI:24400 glycoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24400 CHEBI:24405 glycosylglucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24405 CHEBI:24403 glycosyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24403 CHEBI:24402 glycosphingolipid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24402 GO:0047779 citrate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047779 KEGG_REACTION:R01322|RHEA:21472|MetaCyc:CITRATE--COA-LIGASE-RXN|EC:6.2.1.18 citrate:CoA ligase (ADP-forming)|citrate:CoA ligase activity|citryl-CoA synthetase activity|citrate thiokinase activity Catalysis of the reaction: ATP + citrate + CoA = (3S)-citryl-CoA + ADP + H(+) + phosphate. GO:0047778 [citrate-(pro-3S)-lyase] thiolesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047778 MetaCyc:CITRATE-PRO-3S-LYASE-THIOLESTERASE-RXN|EC:3.1.2.16|RHEA:13657 citrate-(pro-3S)-lyase thioesterase activity|citrate-(pro-3S)-lyase(acetyl-form) hydrolase activity|citrate lyase deacetylase activity|citrate-(pro-3S)-lyase thiolesterase activity|[citrate-(pro-3S)-lyase] thioesterase activity|citrate (pro-3S)-lyase thiolesterase activity Catalysis of the reaction: [citrate (pro-3S)-lyase](acetyl form) + H2O = [citrate (pro-3S)-lyase](thiol form) + acetate. GO:0047777 (S)-citramalyl-CoA lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047777 MetaCyc:CITRAMALYL-COA-LYASE-RXN|EC:4.1.3.25|KEGG_REACTION:R00237|RHEA:22612 (+)-CMA-CoA lyase activity|(3S)-citramalyl-CoA pyruvate-lyase activity|citramalyl-CoA lyase activity|citramalyl coenzyme A lyase activity|(3S)-citramalyl-CoA lyase activity|(3S)-citramalyl-CoA pyruvate-lyase (acetyl-CoA-forming) Catalysis of the reaction: (3S)-citramalyl-CoA = acetyl-CoA + pyruvate. GO:0047776 citramalate lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047776 RHEA:15545|MetaCyc:CITRAMALATE-LYASE-RXN|KEGG_REACTION:R00325|EC:4.1.3.22 citramalic-condensing enzyme|citramalic synthase activity|citramalate pyruvate-lyase activity|(S)-citramalate lyase activity|citramalate synthetase activity|(+)-citramalate pyruvate-lyase activity|(3S)-citramalate pyruvate-lyase activity|citramalate pyruvate lyase activity|(3S)-citramalate pyruvate-lyase (acetate-forming) Catalysis of the reaction: S-citramalate = acetate + pyruvate. GO:0047775 citramalate CoA-transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047775 EC:2.8.3.11|RHEA:17621|MetaCyc:CITRAMALATE-COA-TRANSFERASE-RXN acetyl-CoA:citramalate CoA-transferase activity Catalysis of the reaction: acetyl-CoA + citramalate = acetate + (3S)-citramalyl-CoA. GO:0047774 cis-2-enoyl-CoA reductase (NADPH) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047774 MetaCyc:CIS-2-ENOYL-COA-REDUCTASE-NADPH-RXN|EC:1.3.1.37 acyl-CoA:NADP+ cis-2-oxidoreductase activity|reductase, cis-2-enoyl coenzyme A|NADPH-dependent cis-enoyl-CoA reductase activity|cis-2-enoyl-coenzyme A reductase activity Catalysis of the reaction: acyl-CoA + NADP+ = cis-2,3-dehydroacyl-CoA + NADPH. GO:0047773 carnitinamidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047773 MetaCyc:CARNITINAMIDASE-RXN|RHEA:17537|EC:3.5.1.73|KEGG_REACTION:R01922 carnitine amidase activity|L-carnitinamide amidohydrolase activity|L-carnitinamidase activity|L-carnitine amidase activity Catalysis of the reaction: (R)-carnitinamide + H(2)O = (R)-carnitine + NH(4)(+). GO:0047772 carboxymethyloxysuccinate lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047772 MetaCyc:CARBOXYMETHYLOXYSUCCINATE-LYASE-RXN|EC:4.2.99.12|KEGG_REACTION:R01336|RHEA:12336 carboxymethyloxysuccinate glycolate-lyase activity|carboxymethyloxysuccinate glycolate-lyase (fumarate-forming) Catalysis of the reaction: carboxymethoxysuccinate = fumarate + glycolate. UBERON:0001271 pelvic girdle region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001271 pelvic girdle|girdle - pelvic The organism subdivision that includes the pelvic girdle skeleton and associated soft tissue. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc). Examples: There are only two instances in an organism, right and left pectoral girdle regions. UBERON:0001272 innominate bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001272 coxal bone|pelvic bone|basipterygium|innominate bone|bone of pelvic girdle|innominate|os innominatum|hip bone|os coxae|os coxa A fused bone consisting of the ilium, ischium and and pubis. Together with the sacrum and coccyx, it comprises the pelvis. [WP,modified]. GO:0072739 response to anisomycin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072739 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anisomycin stimulus. GO:0072738 cellular response to diamide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072738 cellular response to N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diamide (N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide) stimulus. GO:0072737 response to diamide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072737 response to N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diamide (N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide) stimulus. GO:0072736 cellular response to tert-butyl hydroperoxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072736 cellular response to t-BOOH|cellular response to 2-methyl-prop-2-yl-hydroperoxide Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tert-butyl hydroperoxide (t-BOOH) stimulus. GO:0072735 response to tert-butyl hydroperoxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072735 response to 2-methyl-prop-2-yl-hydroperoxide|response to t-BOOH Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tert-butyl hydroperoxide (t-BOOH) stimulus. UBERON:0001279 portal triad biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001279 trias hepatica|trias hepatica A multi-organ-part structure that consists of three vessels of the portal lobule including the bile duct, a terminal branch of the hepatic artery and portal vein, and may also include a lymphatic vessel CHEBI:24409 glycosylphosphatidylinositolethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24409 UBERON:0001278 epithelium of large intestine biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001278 epithelial tissue of large intestine|large intestine epithelial tissue|large intestine epithelium|large intestinal epithelium An epithelium that is part of a large intestine [Automatically generated definition]. GO:0072734 cellular response to staurosporine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072734 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a staurosporine stimulus. GO:0072733 response to staurosporine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072733 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a staurosporine stimulus. CHEBI:73373 cobalt(II)-factor III biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73373 CHEBI:24407 glycosyl glycoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24407 GO:0072732 cellular response to calcium ion starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072732 cellular response to calcium starvation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of calcium ions. CHEBI:24406 glycosylglycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24406 GO:0072731 cellular response to papulacandin B biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072731 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a papulacandin B stimulus. GO:0072730 response to papulacandin B biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072730 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a papulacandin B stimulus. UBERON:0001277 intestinal epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001277 epithelium of bowel|epithelial tissue of bowel|bowel epithelial tissue|intestine epithelium|epithelium of intestine|bowel epithelium|epithelial tissue of intestine|intestine epithelial tissue|villous epithelium Epithelial layer that lines the intestine. UBERON:0001276 epithelium of stomach biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001276 gastric epithelium|stomach epithelial tissue|stomach epithelium|ventriculus epithelium|epithelium of ventriculus|epithelial tissue of ventriculus|ventriculus epithelial tissue|epithelial tissue of stomach The epithelial layer of the stomach . GO:0047782 coniferin beta-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047782 MetaCyc:CONIFERIN-BETA-GLUCOSIDASE-RXN|RHEA:12252|EC:3.2.1.126 coniferin beta-D-glucosidase activity|coniferin b-glucosidase activity|coniferin-hydrolyzing beta-glucosidase activity Catalysis of the reaction: H2O + coniferin = D-glucose + coniferol. GO:0047781 citrullinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047781 RHEA:11940|EC:3.5.1.20|MetaCyc:CITRULLINASE-RXN L-citrulline N5-carbamoyldihydrolase activity|citrulline ureidase activity|citrulline hydrolase activity|L-citrulline 5-N-carbamoyldihydrolase activity Catalysis of the reaction: H2O + citrulline = NH3 + CO2 + L-ornithine. CHEBI:73389 O-ureido-L-serine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73389 GO:0047780 citrate dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047780 RHEA:10228|KEGG_REACTION:R01325|MetaCyc:ACONITATEDEHYDR-RXN|MetaCyc:CITRATE-DEHYDRATASE-RXN|EC:4.2.1.3 aconitate hydratase activity|citrate hydro-lyase (cis-aconitate-forming) activity|citrate hydro-lyase activity|citrate hydro-lyase (cis-aconitate-forming) Catalysis of the reaction: citrate = cis-aconitate + H2O. CHEBI:24410 glycosylphosphatidylinositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24410 GO:0047789 creatininase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047789 MetaCyc:CREATININASE-RXN|KEGG_REACTION:R01884|EC:3.5.2.10|RHEA:14533 creatinine amidohydrolase activity|creatinine hydrolase Catalysis of the reaction: creatinine + H(2)O = creatine. GO:0047788 2-coumarate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047788 MetaCyc:COUMARATE-REDUCTASE-RXN|KEGG_REACTION:R03709|EC:1.3.1.11|RHEA:21444 coumarate reductase activity|3-(2-hydroxyphenyl)propanoate:NAD+ oxidoreductase activity|melilotate dehydrogenase activity Catalysis of the reaction: 3-(2-hydroxyphenyl)propanoate + NAD(+) = trans-2-coumarate + H(+) + NADH. GO:0047787 delta4-3-oxosteroid 5beta-reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047787 MetaCyc:CHOLESTENONE-5-BETA-REDUCTASE-RXN|MetaCyc:CORTISONE-BETA-REDUCTASE-RXN|EC:1.3.1.3 cortisone beta-reductase activity|cortisone delta(4)-5-beta-reductase activity|cholestenone 5beta-reductase activity|androstenedione 5beta-reductase activity|testosterone 5beta-reductase activity|delta4-3-ketosteroid 5beta-reductase activity|steroid 5beta-reductase activity|delta4-3-oxosteroid 5-beta-reductase activity|delta(4)-3-ketosteroid 5-beta-reductase activity|5beta-reductase activity|cortisone delta4-5beta-reductase activity|4,5beta-dihydrocortisone:NADP+ delta4-oxidoreductase activity|cholestenone 5-beta-reductase activity|cortisone b-reductase activity|steroid 5-beta-reductase activity|testosterone 5-beta-reductase activity|5-beta-reductase activity|androstenedione 5-beta-reductase activity|cholestenone 5b-reductase activity|delta(4)-5-beta-reductase activity|3-oxo-delta4-steroid 5beta-reductase activity|delta4-hydrogenase activity|cortisone 5beta-reductase activity|3-oxo-Delta(4)-steroid 5-beta-reductase activity|delta4-5beta-reductase activity|3-oxo-5beta-steroid:NADP+ delta4-oxidoreductase activity|5beta-cholestan-3-one:NADP+ 4,5-oxidoreductase activity|cortisone 5-beta-reductase activity|delta(4)-hydrogenase activity Catalysis of the reactions: (1) 5beta-cholestan-3-one + NADP+ = cholest-4-en-3-one + NADPH + H+ and (2) 17,21-dihydroxy-5beta-pregnane-3,11,20-trione + NADP+ = cortisone + NADPH + H+. GO:0047786 cortisone alpha-reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047786 MetaCyc:CORTISONE-ALPHA-REDUCTASE-RXN|KEGG_REACTION:R02892|RHEA:17981 cortisone delta4-5alpha-reductase activity|microsomal steroid reductase (5alpha)|NADPH:Delta4-3-oxosteroid-5alpha-oxidoreductase activity|cortisone a-reductase activity|delta4-3-ketosteroid reductase (5alpha)|4,5alpha-dihydrocortisone:NADP+ delta4-oxidoreductase activity|delta4-3-oxosteroid-5alpha-reductase|delta4-5alpha-reductase activity Catalysis of the reaction: 4,5alpha-dihydrocortisone + NADP(+) = cortisone + H(+) + NADPH. GO:0047785 cortisol sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047785 KEGG_REACTION:R02839|MetaCyc:CORTISOL-SULFOTRANSFERASE-RXN|EC:2.8.2.18|RHEA:11884 3'-phosphoadenylyl-sulfate:cortisol 21-sulfotransferase activity|glucocorticosteroid sulfotransferase activity|cortisol sulphotransferase activity|glucocorticoid sulfotransferase activity Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + cortisol = adenosine 3',5'-diphosphate + cortisol 21-sulfate + H(+). GO:0047784 cortisol O-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047784 EC:2.3.1.27|KEGG_REACTION:R02837|RHEA:17073|MetaCyc:CORTISOL-O-ACETYLTRANSFERASE-RXN corticosteroid-21-O-acetyltransferase activity|corticosteroid acetyltransferase activity|cortisol acetyltransferase activity|acetyl-CoA:cortisol O-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + cortisol = CoA + cortisol 21-acetate. GO:0047783 corticosterone 18-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047783 MetaCyc:CORTICOSTERONE-18-MONOOXYGENASE-RXN|RHEA:11872|EC:1.14.15.5 corticosterone 18-hydroxylase activity|corticosterone,reduced-adrenal-ferredoxin:oxygen oxidoreductase (18-hydroxylating)|corticosterone methyl oxidase activity Catalysis of the reaction: corticosterone + reduced adrenal ferredoxin + O2 = 18-hydroxycorticosterone + oxidized adrenal ferredoxin + H2O. UBERON:0001260 serosa of urinary bladder biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001260 serosa of bladder|serous membrane of urinary bladder|bladder serosa|serous membrane of bladder|urinary bladder serosa|urinary bladder serous membrane|serous coat of urinary bladder|tunica serosa (vesica urinaria)|bladder serous membrane|serous coat of bladder|visceral peritoneum of urinary bladder|tunica serosa vesicae A serous membrane that is part of a urinary bladder [Automatically generated definition]. UBERON:0001262 wall of intestine biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001262 anatomical wall of bowel|intestine wall|wall of bowel|anatomical wall of intestine|bowel wall|bowel anatomical wall|bowel wall|intestine anatomical wall|intestinal wall An anatomical wall that is part of a intestine [Automatically generated definition]. UBERON:0001261 lamina propria of urinary bladder biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001261 urinary bladder lamina propria|urinary bladder lamina propria mucosa|bladder lamina propria mucosa|lamina propria mucosae of urinary bladder|lamina propria of bladder|lamina propria mucosae of bladder|lamina propria mucosa of urinary bladder|bladder lamina propria mucosae|bladder lamina propria|lamina propria mucosa of bladder|urinary bladder lamina propria mucosae A lamina propria that is part of a urinary bladder [Automatically generated definition]. GO:0072729 cellular response to Gentian violet biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072729 cellular response to crystal violet|cellular response to {4-[Bis-(4-dimethylamino-phenyl)-methylene]-cyclohexa-2,5-dienylidene}-dimethyl-ammonium chloride Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Gentian violet stimulus. GO:0072728 response to Gentian violet biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072728 response to crystal violet|response to {4-[Bis-(4-dimethylamino-phenyl)-methylene]-cyclohexa-2,5-dienylidene}-dimethyl-ammonium chloride Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Gentian violet stimulus. GO:0072727 cellular response to CCCP biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072727 cellular response to carbonyl cyanide m-chlorophenyl hydrazone Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a CCCP stimulus. GO:0072726 response to CCCP biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072726 response to carbonyl cyanide m-chlorophenyl hydrazone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a CCCP stimulus. GO:0072725 cellular response to 4-nitroquinoline N-oxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072725 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4-nitroquinoline N-oxide stimulus. UBERON:0001268 peritoneal fluid biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001268 Transudate contained in the peritoneal cavity. GO:0072724 response to 4-nitroquinoline N-oxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072724 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4-nitroquinoline N-oxide stimulus. GO:0072723 cellular response to amitrole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072723 cellular response to 3-amino-1,2,4-triazole Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amitrole stimulus. GO:0072722 response to amitrole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072722 response to 3-amino-1,2,4-triazole Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amitrole stimulus. GO:0072721 cellular response to dithiothreitol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072721 cellular response to DTT|cellular response to 1,4-dithiothreitol Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dithiothreitol stimulus. GO:0072720 response to dithiothreitol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072720 response to 1,4-dithiothreitol|response to DTT Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dithiothreitol stimulus. UBERON:0001264 pancreas biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001264 An endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating enzymes[GO]. UBERON:0001263 pancreatic acinus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001263 acinus pancreaticus|pancreas acinus|pancreatic acinar|pancreatic acini The secretory units of the exocrine pancreas, where fluid containing digestive enzymes is produced; consists of a group of secretory cells surrounding a luminal space that connects to the pancreatic duct. CHEBI:73388 caldariellaquinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73388 UBERON:0001265 trabecula of spleen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001265 splenic trabecula|spleen trabeculum A trabecula that is part of a spleen. CHEBI:73387 caldariellaquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73387 GO:0047793 cycloeucalenol cycloisomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047793 RHEA:22800|MetaCyc:CYCLOEUCALENOL-CYCLOISOMERASE-RXN|EC:5.5.1.9|KEGG_REACTION:R03775 cycloeucalenol lyase (cyclopropane-decyclizing)|cycloeucalenol--obtusifoliol isomerase activity|cycloeucalenol-obtusifoliol isomerase activity Catalysis of the reaction: cycloeucalenol = obtusifoliol. GO:0047792 cyanohydrin beta-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047792 RHEA:12853|EC:2.4.1.85 uridine diphosphoglucose:aldehyde cyanohydrin beta-glucosyltransferase activity|uridine diphosphoglucose-cyanohydrin glucosyltransferase activity|UDP-glucose-p-hydroxymandelonitrile glucosyltransferase activity|UDP-glucose:p-hydroxymandelonitrile-O-glucosyltransferase activity|UDP-glucose:(S)-4-hydroxymandelonitrile beta-D-glucosyltransferase activity|uridine diphosphoglucose-p-hydroxymandelonitrile glucosyltransferase activity|UGT85B1 activity|cyanohydrin b-glucosyltransferase activity|UDP-D-glucose:(S)-4-hydroxymandelonitrile beta-D-glucosyltransferase activity Catalysis of the reaction: UDP-glucose + (S)-4-hydroxymandelonitrile = UDP + (S)-4-hydroxy-mandelonitrile beta-D-glucoside. GO:0047791 cucurbitacin delta23-reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047791 EC:1.3.1.5|MetaCyc:CUCURBITACIN-DELTA-23-REDUCTASE-RXN 23,24-dihydrocucurbitacin:NAD(P)+ delta23-oxidoreductase activity|NAD(P)H: cucurbitacin B delta23-oxidoreductase activity|cucurbitacin delta(23) reductase activity|cucurbitacin D23-reductase activity Catalysis of the reaction: 23,24-dihydrocucurbitacin + NAD(P)+ = cucurbitacin + NAD(P)H + H+. GO:0047790 creatinine deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047790 MetaCyc:CREATININE-DEAMINASE-RXN|EC:3.5.4.21|RHEA:12681 creatinine hydrolase|creatinine iminohydrolase activity|creatinine desiminase activity Catalysis of the reaction: creatinine + H2O = N-methylhydantoin + NH3. UBERON:0001249 spleen lymphoid follicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001249 spleen lymphoid follicle|splenic lymphatic follicle|lymphoid nodule of spleen|lymphatic follicle of spleen|Malpighian body|splenic lymphoid follicle|spleen B cell follicle|spleen lymphoid nodule|lymphoid follicle of spleen|splenic B cell follicle The area of the white pulp where the affinity maturation of B cells and the generation of memory B cells and plasma cells occur GO:0047799 cyclopentanone monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047799 EC:1.14.13.16|MetaCyc:CYCLOPENTANONE-MONOOXYGENASE-RXN|RHEA:15737|KEGG_REACTION:R02554 cyclopentanone oxygenase activity|cyclopentanone 1,2-monooxygenase activity|cyclopentanone,NADPH:oxygen oxidoreductase (5-hydroxylating, lactonizing) Catalysis of the reaction: cyclopentanone + H(+) + NADPH + O(2) = 5-valerolactone + H(2)O + NADP(+). GO:0047798 cyclomaltodextrinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047798 MetaCyc:CYCLOMALTODEXTRINASE-RXN|RHEA:23980|EC:3.2.1.54 cycloheptaglucanase activity|cyclodextrinase activity|cyclomaltodextrin dextrin-hydrolase (decyclizing)|cyclohexaglucanase activity Catalysis of the reaction: H2O + cyclomaltodextrin = linear maltodextrin. GO:0047797 cyclohexanone dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047797 RHEA:21780|EC:1.3.99.14|MetaCyc:CYCLOHEXANONE-DEHYDROGENASE-RXN|KEGG_REACTION:R02234 cyclohexanone:acceptor 2-oxidoreductase activity|cyclohexanone:(acceptor) 2-oxidoreductase activity Catalysis of the reaction: A + cyclohexanone = AH(2) + cyclohex-2-enone. GO:0047796 cyclohexane-1,3-dione hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047796 RHEA:16473|MetaCyc:CYCLOHEXANE-13-DIONE-HYDROLASE-RXN|EC:3.7.1.10|KEGG_REACTION:R03211 1,3-cyclohexanedione hydrolase activity|cyclohexane-1,3-dione acylhydrolase (decyclizing) Catalysis of the reaction: cyclohexane-1,3-dione + H(2)O = 5-oxohexanoate + H(+). GO:0047795 cyclohexane-1,2-diol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047795 RHEA:18141|MetaCyc:CYCLOHEXANE-12-DIOL-DEHYDROGENASE-RXN|EC:1.1.1.174 trans-cyclohexane-1,2-diol:NAD+ 1-oxidoreductase activity Catalysis of the reaction: trans-cyclohexane-1,2-diol + NAD+ = 2-hydroxycyclohexan-1-one + NADH. GO:0047794 cyclohexadienyl dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047794 MetaCyc:CYCLOHEXADIENYL-DEHYDROGENASE-RXN|EC:1.3.1.43|RHEA:12256 L-arogenate:NAD(+) oxidoreductase activity|pretyrosine dehydrogenase activity|L-arogenate:NAD+ oxidoreductase (decarboxylating)|arogenate dehydrogenase activity|L-arogenate:NAD+ oxidoreductase activity|arogenic dehydrogenase activity Catalysis of the reaction: L-arogenate + NAD+ = L-tyrosine + NADH + CO2. GO:0072759 cellular response to topoisomerase inhibitor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072759 Any process that results in a change in state or activity of a (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a topoisomerase inhibitor stimulus. GO:0072758 response to topoisomerase inhibitor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072758 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a topoisomerase inhibitor stimulus. UBERON:0025261 thalamic fiber tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0025261 thalamic fiber tracts GO:0072757 cellular response to camptothecin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072757 cellular response to CPT Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a camptothecin stimulus. UBERON:0001256 wall of urinary bladder biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001256 anatomical wall of bladder|urinary bladder anatomical wall|wall of bladder|bladder anatomical wall|bladder wall|urinary bladder wall|anatomical wall of urinary bladder An anatomical wall that lines the insider of a urinary bladder. GO:0072756 cellular response to paraquat biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072756 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paraquat stimulus. GO:0072755 cellular response to benomyl biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072755 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benomyl stimulus. UBERON:0001259 mucosa of urinary bladder biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001259 tunica mucosa (vesica urinaria)|bladder organ mucosa|urinary bladder mucous membrane|tunica mucosa vesicae|bladder mucous membrane|tunica mucosa vesicae urinariae|mucous membrane of urinary bladder|bladder mucosa|mucous membrane of bladder|mucosa of bladder|urinary bladder mucosa the mucous membrane lining the urinary bladder UBERON:0001258 neck of urinary bladder biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001258 vesical neck|urinary bladder neck|cervix vesicae urinariae|collum vesicae|neck of bladder|bladder neck|cervix vesicae The constricted portion of the urinary bladder, formed by the meeting of its inferolateral surfaces proximal to the opening of the urethra[MP]. GO:0072754 cellular response to purvalanol A biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072754 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purvalanol A stimulus. CHEBI:324935 fumagillol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_324935 UBERON:0001253 lamina propria of ureter biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001253 ureter lamina propria|lamina propria mucosae of ureter|ureter lamina propria mucosa|lamina propria mucosa of ureter|ureter lamina propria mucosae A lamina propria that is part of a ureter [Automatically generated definition]. GO:0072753 cellular response to glutathione biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072753 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glutathione stimulus. UBERON:0001252 adventitia of ureter biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001252 external adventitia of ureter|tunica adventitia (ureter)|tunica adventitia ureteris|ureter adventitia|ureteral adventitia An adventitia that is part of a ureter. GO:0072752 cellular response to rapamycin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072752 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rapamycin stimulus. GO:0072751 cellular response to L-thialysine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072751 cellular response to thialysine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-thialysine stimulus. UBERON:0001255 urinary bladder biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001255 vesica urinaria|urocyst|vesica|bladder distensible musculomembranous organ situated in the anterior part of the pelvic cavity in which urine collects before excretion[MP]. UBERON:0001254 urothelium of ureter biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001254 transitional epithelium of ureter|ureter luminal urothelium|ureter transitional epithelium|ureter urothelium The luminal epithelium of the tube that conducts the urine from the renal pelvis to the bladder[MP] GO:0072750 cellular response to leptomycin B biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072750 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptomycin B stimulus. CHEBI:73398 indole skeleton biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73398 UBERON:0001238 lamina propria of small intestine biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001238 lamina propria mucosae of small intestine|lamina propria mucosa of small bowel|small bowel lamina propria mucosae|small bowel lamina propria|lamina propria of mucosa of small intestine|lamina propria mucosa of small intestine|small bowel lamina propria mucosa|small intestine lamina propria mucosa|lamina propria of small bowel|lamina propria mucosae of small bowel|small intestine lamina propria mucosae|small intestine lamina propria Lamina propria that is part_of the small intestine. GO:0072749 cellular response to cytochalasin B biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072749 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytochalasin B stimulus. GO:0072748 cellular response to tacrolimus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072748 cellular response to FK506|cellular response to tacrolimus hydrate Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tacrolimus (FK506) stimulus. GO:0072747 cellular response to chloramphenicol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072747 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloramphenicol stimulus. GO:0072746 cellular response to tetracycline biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072746 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetracycline stimulus. UBERON:0001246 interlobular bile duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001246 interlobular ductule The canals that carry bile in the liver between the intralobular ducts and the biliary ductules; interlobular bile ducts are part of the interlobular portal triad. GO:0072745 cellular response to antimycin A biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072745 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimycin A stimulus. UBERON:0001245 anus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001245 proctodeum|anal orifice|anal opening|opening of terminal part of digestive tract Orifice at the opposite end of an animal's digestive tract from the mouth. Its function is to expel feces, unwanted semi-solid matter produced during digestion, which, depending on the type of animal, may be one or more of: matter which the animal cannot digest, such as bones; food material after all the nutrients have been extracted, for example cellulose or lignin; ingested matter which would be toxic if it remained in the digestive tract; and dead or excess gut bacteria and other endosymbionts. GO:0072744 cellular response to trichodermin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072744 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichodermin stimulus. GO:0072743 cellular response to erythromycin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072743 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythromycin stimulus. UBERON:0001247 falciform ligament biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001247 falciform ligament of liver|ligamentum falciforme (hepatis)|ligamentum falciforme hepatis A ligament that attaches the liver to the anterior body wall. It is a broad and thin antero-posterior peritoneal fold, falciform in shape, its base being directed downward and backward and its apex upward and backward. It is a remnant of the ventral mesentery of the fetus. It is situated in an antero-posterior plane but lies obliquely, so that one surface faces forward and is in contact with the peritoneum behind the right rectus and the diaphragm, while the other is directed backward and is in contact with the left lobe of the liver. It is attached by its left margin to the under surface of the diaphragm and the posterior surface of the sheath of the right Rectus as low down as the umbilicus; by its right margin it extends from the notch on the anterior margin of the liver, as far back as the posterior surface. It is composed of two layers of peritoneum closely united together. Its base or free edge contains between its layers the round ligament and the paraumbilical veins[WP]. UBERON:0001242 intestinal mucosa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001242 mucosa of bowel|mucosa of organ of bowel|bowel organ mucosa|mucous membrane of intestine|mucosa of intestine|mucosa of organ of intestine|intestine mucosa|bowel mucosa of organ|organ mucosa of bowel|tunica mucosa intestini|bowel mucous membrane|bowel mucosa|intestine mucosa of organ|organ mucosa of intestine|intestine mucous membrane|intestine organ mucosa|mucous membrane of bowel Mucosal layer that lines the intestine. GO:0072742 SAGA complex localization to transcription regulatory region biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072742 SAGA complex localization to promoter|SAGA complex recruitment Any process in which a SAGA complex is transported to, or maintained in, a specific location in the transcription regulatory region of a gene. GO:0072741 protein localization to cell division site biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072741 protein localisation to cell division site A cellular protein localization process in which a protein is transported to, or maintained at, the site of cell division. GO:0072740 cellular response to anisomycin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072740 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anisomycin stimulus. UBERON:0001243 serosa of intestine biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001243 visceral peritoneum of intestine|bowel anatomical wall serosa|anatomical wall of intestine serosa|wall of bowel serous membrane|bowel wall serosa|serous membrane of intestine anatomical wall|anatomical wall of intestine serous membrane|wall of bowel serosa|serosa of bowel wall|bowel wall serous membrane|serosa of anatomical wall of intestine|bowel anatomical wall serous membrane|serosa of intestinal wall|intestine wall serosa|anatomical wall of bowel serosa|wall of intestine serous membrane|intestinal wall serosa|serosa of wall of bowel|intestinal serosa|intestine anatomical wall serous membrane|intestine serosa|serous membrane of intestinal wall|serosa of bowel anatomical wall|serous membrane of anatomical wall of bowel|serosa of wall of intestine|serous membrane of intestine wall|serous membrane of wall of bowel|intestine anatomical wall serosa|serosa of intestine anatomical wall|intestinal wall serous membrane|serous membrane of bowel anatomical wall|serous membrane of anatomical wall of intestine|serous membrane of bowel wall|intestine wall serous membrane|serous membrane of wall of intestine|serosa of anatomical wall of bowel|anatomical wall of bowel serous membrane|serosa of intestine wall|wall of intestine serosa A serous membrane that is part of a wall of intestine [Automatically generated definition]. UBERON_CORE:channels_into channels_into biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/uberon/core#channels_into channels_into OBA:1000028 membrane permeability biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_1000028 permeability of membrane|membrane permeability trait The permeability of a membrane. CHEBI:310312 isoliquiritigenin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_310312 SO:0000235 TF_binding_site biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000235 TF binding site|transcription factor binding site A DNA site where a transcription factor binds. SO:0000234 mRNA biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000234 http://en.wikipedia.org/wiki/MRNA|http://www.gencodegenes.org/gencode_biotypes.html messenger RNA|protein_coding_transcript|INSDC_feature:mRNA Messenger RNA is the intermediate molecule between DNA and protein. It includes UTR and coding sequences. It does not contain introns. GO:0072760 cellular response to GW 7647 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072760 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a GW 7647 stimulus. OBA:1000035 lens of camera-type eye opacity biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_1000035 lens of camera-type eye opacity trait|lens opacity|opacity of lens of camera-type eye|lens transparency The opacity of a lens of camera-type eye. SO:0000233 mature_transcript biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000233 http://en.wikipedia.org/wiki/Mature_transcript mature transcript A transcript which has undergone the necessary modifications, if any, for its function. In eukaryotes this includes, for example, processing of introns, cleavage, base modification, and modifications to the 5' and/or the 3' ends, other than addition of bases. In bacteria functional mRNAs are usually not modified. GO:0072766 centromere clustering at the mitotic interphase nuclear envelope biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072766 centromere clustering at the mitotic nuclear envelope|centromere-SPB clustering|rabl configuration|kinetochore localization at spindle pole body|kinetochore clustering at spindle pole body|centromere clustering at the nuclear periphery|kinetochore clustering at SPB|kinetochore clustering at the old mitotic spindle pole body The process in which chromatin, or kinetochores are anchored to the nuclear envelope. This process involves the microtubule cytoskeleton, and nuclear tethering factors and is responsible for the Rabl-like configuration of chromosomes in the interphase nuclei. GO:0072765 centromere localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072765 establishment and maintenance of kinetochore localization|kinetochore localisation|kinetochore localization A cellular localization process in which a centromere/kinetochore is transported to, or maintained in, a specific location. GO:0072764 cellular response to reversine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072764 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reversine stimulus. UBERON:4200230 surface of bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_4200230 bone surface An anatomical surface that is part of a bone GO:0072763 cellular response to hesperadin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072763 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hesperadin stimulus. GO:0072762 cellular response to carbendazim biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072762 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbendazim stimulus. GO:0072761 cellular response to capsazepine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072761 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a capsazepine stimulus. UBERON:0001293 outer medulla of kidney biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001293 kidney outer medulla|set of outer region of renal pyramids|zona externa (medullaris renalis)|outer zone of renal medulla|outer zone of medulla of kidney|renal outer medulla|outer renal medulla|zona externa medullae renalis The renal outer medulla is the region of the kidney that lies between the renal cortex and the renal inner medulla[GO]. UBERON:0001292 distal convoluted tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001292 distal convoluted renal tubule|tubulus contortus distalis|tubulus contortus distalis|tubulus convolutus distalis|second convoluted tubule The first segment of the nephron lying just downstream from the loop of Henle, immediately after the macula densa. UBERON:2001269 regenerating fin/limb biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_2001269 regenerating fins Fin or limb undergoing the process of regeneration. UBERON:0001295 endometrium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001295 uterine endometrium|uterine mucosa|tunica mucosa uteri|tunica mucosa (endometrium)|uterine mucous membrane the glandular mucous membrane lining of the uterine cavity that is hormonally responsive during the estrous/menstrual cycle and during pregnancy UBERON:0001294 inner medulla of kidney biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001294 zona interna medullae renalis|kidney inner medulla|inner zone of renal medulla|inner zone of medulla of kidney|zona interna (medullaris renalis)|renal inner medulla|inner renal medulla|set of inner region of renal pyramids Innermost region of the mammalian kidney. UBERON:0001291 thick ascending limb of loop of Henle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001291 tubulus rectus distalis|distal straight tubule|ascending thick limb|thick ascending limb|straight portion of distal convoluted tubule|thick ascending limb of distal tubule|thick ascending limb of Henle's loop|straight portion of distal convoluted renal tubule|tubulus rectus distalis|loop of Henle ascending limb thick segment the distal sub-portion of the ascending loop of Henle which is lined by simple cuboidal epithelium and enters the renal cortex to empty a hypotonic filtrate into the distal convoluted tubule UBERON:0001290 proximal straight tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001290 pars recta|S3|segment 3 of proximal tubule|tubulus rectus proximalis|proximal tubule segment 3|thick descending limb of proximal tubule|pars recta tubuli renalis The proximal straight tubule is the part of the descending limb that extends from the proximal convoluted tubule to the descending thin tubule. UBERON:0001297 serosa of uterus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001297 visceral peritoneum of uterus|uterine serosa|serous coat of uterus|tunica serosa uteri|perimetrium|serous membrane of uterus|tunica serosa (perimetrium)|uterus serosa|uterus serous membrane Outer serosa layer of the uterus. UBERON:0001299 glans penis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001299 coronal sulcus|glans|balanus the conic expansion of the corpus spongiosum that forms the head of the penis SO:0000253 tRNA biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000253 http://en.wikipedia.org/wiki/TRNA transfer RNA|INSDC_feature:tRNA|transfer ribonucleic acid|INSDC_qualifier:unknown Transfer RNA (tRNA) molecules are approximately 80 nucleotides in length. Their secondary structure includes four short double-helical elements and three loops (D, anti-codon, and T loops). Further hydrogen bonds mediate the characteristic L-shaped molecular structure. Transfer RNAs have two regions of fundamental functional importance: the anti-codon, which is responsible for specific mRNA codon recognition, and the 3' end, to which the tRNA's corresponding amino acid is attached (by aminoacyl-tRNA synthetases). Transfer RNAs cope with the degeneracy of the genetic code in two manners: having more than one tRNA (with a specific anti-codon) for a particular amino acid; and 'wobble' base-pairing, i.e. permitting non-standard base-pairing at the 3rd anti-codon position. SO:0000252 rRNA biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0000252 http://en.wikipedia.org/wiki/RRNA ribosomal ribonucleic acid|INSDC_feature:rRNA|INSDC_qualifier:unknown|ribosomal RNA RNA that comprises part of a ribosome, and that can provide both structural scaffolding and catalytic activity. OBA:1000019 nucleus morphology biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_1000019 nucleus morphology trait|morphology of nucleus The morphology of a nucleus. UBERON:0001282 intralobular bile duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001282 cholangiole|duct of Herring|canal of Hering|canals of Hering|intrahepatic bile ductule|ductus interlobularis bilifer|canal of Herring the tubules located between the bile canaliculi and interlobular bile ducts near the outer edge of a classic liver lobule UBERON:0001281 hepatic sinusoid biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001281 hepatic sinusoids|vas sinusoideum|liver sinusoid|vas capillare sinusoideum|sinusoid of liver|liver hepatic sinusoids|liver sinusoidal blood vessel|sinusoidal blood vessel of liver Wide thin-walled blood vessels in the liver. In mammals they have neither veinous or arterial markers. UBERON:0001283 bile canaliculus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001283 bile canaliculi|bile capillary|biliary canaliculus An intercellular channel that takes up bile from hepatocytes, transporting it to the bile ducts. UBERON:0001280 liver parenchyma biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001280 hepatic parenchyme|liver parenchyme|parenchyma of liver|hepatic parenchyma The functional units of the liver including the lobules. UBERON:0001289 descending limb of loop of Henle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001289 loop of Henle descending limb|descending limb of Henle's loop|descending limb the portion of the renal tubule that constitutes the proximal part of the loop of Henle, has low permeability to ions and urea, and is highly permeable to water; it consists of an initial short thick segment lined by low simple cuboidal epithelium and a long thin segment lined by simple squamous epithelium; however, this distinction is not as important physiologically as in the ascending limb, so often the two are treated as one structure UBERON:0001285 nephron biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001285 nephroneum|mature nephron|tubulus renalis The basic functional unit of the kidney. its chief function is to regulate the concentration of water and soluble substances like sodium salts by filtering the blood, reabsorbing what is needed and excreting the rest as urine. A nephron eliminates wastes from the body, regulates blood volume and blood pressure, controls levels of electrolytes and metabolites, and regulates blood pH. Its functions are vital to life and are regulated by the endocrine system by hormones such as antidiuretic hormone, aldosterone, and parathyroid hormone.[WP] UBERON:0001288 loop of Henle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001288 Henle loop|Henle's loop|ansa nephroni the section of the renal tubule in the kidney medulla with a hairpin bend; consists of a descending limb and an ascending limb, and is situated between the proximal convoluted tubule to the distal convoluted tubule; it functions to reabsorb water and ions from the urine UBERON:0001287 proximal convoluted tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001287 PCT|kidney proximal convoluted tubule|proximal convoluted renal tubule|tubulus contortus proximalis|renal proximal convoluted tubule|tubulus contortus proximalis|1st convoluted tubule|first convoluted tubule|tubulus convolutus proximalis The proximal convoluted tubule is the most proximal portion of the proximal tubule and extends from the glomerular capsule to the proximal straight tubule. GO:0008329 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008329 GO:0008328 ionotropic glutamate receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0008328 A multimeric assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand-gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. GO:0008327 methyl-CpG binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008327 Interacting selectively and non-covalently with a methylated cytosine/guanine dinucleotide. GO:0008326 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008326 GO:0008325 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008325 GO:0047933 glucose-1,6-bisphosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047933 MetaCyc:GLUCOSE-16-BISPHOSPHATE-SYNTHASE-RXN|Reactome:R-HSA-8955760|RHEA:16769|EC:2.7.1.106|KEGG_REACTION:R01660 3-phospho-D-glyceroyl-phosphate:D-glucose-1-phosphate 6-phosphotransferase activity|glucose 1,6-diphosphate synthase activity|glucose-1,6-bisphosphate synthetase activity|3-phospho-D-glyceroyl-phosphate:alpha-D-glucose-1-phosphate 6-phosphotransferase activity Catalysis of the reaction: 3-phospho-D-glyceroyl phosphate + alpha-D-glucose 1-phosphate = 3-phospho-D-glycerate + alpha-D-glucose 1,6-bisphosphate + H(+). GO:0047932 glucosamine N-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047932 KEGG_REACTION:R01204|RHEA:21332|EC:2.3.1.3|MetaCyc:GLUCOSAMINE-N-ACETYLTRANSFERASE-RXN glucosamine acetyltransferase activity|acetyl-CoA:D-glucosamine N-acetyltransferase activity|glucosamine acetylase activity Catalysis of the reaction: D-glucosamine + acetyl-CoA = N-acetyl-D-glucosamine + CoA + H(+). GO:0008324 cation transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008324 transmembrane cation transporter activity Enables the transfer of cation from one side of a membrane to the other. GO:0047931 glucosamine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047931 RHEA:10948|EC:2.7.1.8|MetaCyc:GLUCOSAMINE-KINASE-RXN ATP:D-glucosamine phosphotransferase activity|glucosamine kinase (phosphorylating)|aminodeoxyglucose kinase activity|ATP:2-amino-2-deoxy-D-glucose-6-phosphotransferase activity Catalysis of the reaction: ATP + D-glucosamine = ADP + D-glucosamine phosphate. GO:0008323 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008323 GO:0047930 glucosaminate ammonia-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047930 EC:4.3.1.9|RHEA:12488|MetaCyc:4.3.1.21-RXN glucosaminic dehydrase activity|D-glucosaminate ammonia-lyase (isomerizing; 2-dehydro-3-deoxy-D-gluconate-forming)|D-glucosaminate dehydratase activity|aminodeoxygluconate ammonia-lyase activity|2-amino-2-deoxy-D-gluconate ammonia-lyase activity|D-glucosaminic acid dehydrase activity|aminodeoxygluconate dehydratase activity|2-amino-2-deoxy-D-gluconate hydro-lyase (deaminating) activity|acetylenemonocarboxylic acid hydrase activity|D-glucosaminate ammonia-lyase activity Catalysis of the reaction: D-glucosaminate = 2-dehydro-3-deoxy-D-gluconate + NH3. GO:0008322 obsolete Pro-X carboxypeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008322 Pro-X carboxypeptidase activity OBSOLETE. Catalysis of the cleavage of a Pro-Xaa bond to release a C-terminal amino acid. CHEBI:83579 3-(methylthio)propanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83579 CHEBI:83578 2-carboxyhexacosanoyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83578 GO:0008321 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008321 GO:0008320 protein transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008320 Reactome:R-HSA-5229111|Reactome:R-HSA-5250616|Reactome:R-HSA-5205661|Reactome:R-HSA-1268022|Reactome:R-HSA-5246514|Reactome:R-HSA-5244506|Reactome:R-HSA-5228406|Reactome:R-HSA-5244428|Reactome:R-HSA-5250972|Reactome:R-HSA-5250884|Reactome:R-HSA-184269|Reactome:R-HSA-5244404|Reactome:R-HSA-5336420|Reactome:R-HSA-5210947|Reactome:R-HSA-3149434|Reactome:R-HSA-9698933|Reactome:R-HSA-1299475|Reactome:R-HSA-9698930|Reactome:R-HSA-5210943|Reactome:R-HSA-9636375 protein channel activity Enables the transfer of a protein from one side of a membrane to the other. CHEBI:83577 2-carboxytetracosanoyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83577 CHEBI:83575 monofluorobenzenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83575 CHEBI:83574 (R)-3,5-bisphosphomevalonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83574 GO:0047939 L-glucuronate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047939 MetaCyc:GLUCURONATE-REDUCTASE-RXN|EC:1.1.1.19|RHEA:14909|KEGG_REACTION:R01481|Reactome:R-HSA-5661256 TPN-L-gulonate dehydrogenase activity|aldehyde reductase II activity|D-glucuronate dehydrogenase activity|D-glucuronate reductase activity|glucuronate reductase activity|glucuronate dehydrogenase activity|NADP-L-gulonate dehydrogenase activity Catalysis of the reaction: L-gulonate + NADP(+) = D-glucuronate + H(+) + NADPH. GO:0047938 glucose-6-phosphate 1-epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047938 EC:5.1.3.15|RHEA:16249|MetaCyc:GLUCOSE-6-PHOSPHATE-1-EPIMERASE-RXN glucose-6 phosphate 1-epimerase activity|D-glucose-6-phosphate 1-epimerase activity Catalysis of the reaction: alpha-D-glucose 6-phosphate = beta-D-glucose 6-phosphate. GO:0047937 glucose-1-phosphate phosphodismutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047937 MetaCyc:GLUCOSE-1-PHOSPHATE-PHOSPHODISMUTASE-RXN|EC:2.7.1.41|RHEA:16397 phosphodismutase activity|D-glucose-1-phosphate:D-glucose-1-phosphate 6-phosphotransferase activity|glucose 1-phosphate transphosphorylase activity Catalysis of the reaction: 2 D-glucose 1-phosphate = D-glucose + D-glucose 1,6-bisphosphate. GO:0047936 glucose 1-dehydrogenase [NAD(P)] activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047936 EC:1.1.1.47|MetaCyc:GLUCOSE-1-DEHYDROGENASE-RXN D-glucose dehydrogenase (NAD(P))|hexose phosphate dehydrogenase activity|beta-D-glucose:NAD(P)+ 1-oxidoreductase activity Catalysis of the reaction: beta-D-glucose + NAD(P)+ = D-glucono-1,5-lactone + NAD(P)H. GO:0047935 glucose 1-dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047935 RHEA:14405|EC:1.1.1.119|MetaCyc:GLUCOSE-1-DEHYDROGENASE-NADP+-RXN D-glucose:NADP+ 1-oxidoreductase activity|nicotinamide adenine dinucleotide phosphate-linked aldohexose dehydrogenase activity|NADP-linked aldohexose dehydrogenase activity|NADP-dependent glucose dehydrogenase activity Catalysis of the reaction: D-glucose + NADP+ = D-glucono-1,5-lactone + NADPH. GO:0047934 glucose 1-dehydrogenase (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047934 EC:1.1.1.118|RHEA:14293|MetaCyc:GLUCOSE-1-DEHYDROGENASE-NAD+-RXN D-glucose:NAD+ 1-oxidoreductase activity|D-aldohexose dehydrogenase activity|D-glucose:NAD oxidoreductase activity Catalysis of the reaction: D-glucose + NAD+ = D-glucono-1,5-lactone + NADH. GO:0008339 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008339 GO:0008338 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008338 GO:0008337 obsolete selectin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008337 selectin OBSOLETE. A class of cell adhesion molecules that bind to carbohydrate via a lectin-like domain; integral membrane glycoproteins. GO:0008336 gamma-butyrobetaine dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008336 MetaCyc:1.14.11.1-RXN|EC:1.14.11.1|RHEA:24028|KEGG_REACTION:R02397|Reactome:R-HSA-71261 alpha-butyrobetaine hydroxylase activity|gamma-butyrobetaine hydroxylase activity|gamma-butyrobetaine,2-oxoglutarate dioxygenase activity|butyrobetaine hydroxylase activity|g-butyrobetaine dioxygenase activity|4-trimethylammoniobutanoate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)|gamma-BBH activity Catalysis of the reaction: 2-oxoglutarate + 4-(trimethylammonio)butanoate + O(2) = carnitine + CO(2) + succinate. GO:0047944 obsolete glutamate 1-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047944 ATP:L-glutamate 1-phosphotransferase activity OBSOLETE. Catalysis of the reaction: L-glutamate + ATP = alpha-L-glutamyl phosphate + ADP + H(+). GO:0047943 glutamate-methylamine ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047943 EC:6.3.4.12|RHEA:17117|MetaCyc:GLUTAMATE--METHYLAMINE-LIGASE-RXN|KEGG_REACTION:R01585 L-glutamate:methylamine ligase (ADP-forming)|gamma-glutamylmethylamide synthetase activity Catalysis of the reaction: L-glutamate + ATP + methylammonium = N(5)-methyl-L-glutamine + ADP + 2 H(+) + phosphate. GO:0008335 female germline ring canal stabilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008335 ovarian ring canal stabilization|nurse cell ring canal stabilization Maintenance of the structural integrity of the ring canals connecting the female germline cyst. GO:0047942 glutamate-ethylamine ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047942 EC:6.3.1.6|MetaCyc:GLUTAMATE--ETHYLAMINE-LIGASE-RXN|KEGG_REACTION:R02929|RHEA:20525 L-glutamate:ethylamine ligase (ADP-forming)|N(5)-ethyl-L-glutamine synthetase activity|N5-ethylglutamine synthetase activity|N5-ethyl-L-glutamine synthetase activity|theanine synthetase activity Catalysis of the reaction: L-glutamate + ATP + ethylamine = N(5)-ethyl-L-glutamine + ADP + 2 H(+) + phosphate. GO:0008334 histone mRNA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008334 histone mRNA metabolism|stem-loop-containing histone mRNA 3'-end processing The chemical reactions and pathways involving an mRNA encoding a histone. GO:0047941 glucuronolactone reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047941 KEGG_REACTION:R03183|MetaCyc:GLUCURONOLACTONE-REDUCTASE-RXN|EC:1.1.1.20|RHEA:18925 Catalysis of the reaction: L-gulono-1,4-lactone + NADP(+) = D-glucurono-3,6-lactone + H(+) + NADPH. GO:0008333 endosome to lysosome transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008333 The directed movement of substances from endosomes to lysosomes. GO:0047940 glucuronokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047940 RHEA:17005|MetaCyc:GLUCURONOKINASE-RXN|KEGG_REACTION:R01476|EC:2.7.1.43 ATP:D-glucuronate 1-phosphotransferase activity|glucurono-glucuronokinase activity|glucuronokinase (phosphorylating) Catalysis of the reaction: D-glucuronate + ATP = 1-phospho-alpha-D-glucuronate + ADP + 2 H(+). GO:0008332 low voltage-gated calcium channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008332 T-type calcium channel|low voltage-dependent calcium channel activity|low voltage gated calcium channel activity Enables the transmembrane transfer of a calcium ion by a low voltage-gated channel. A low voltage-gated channel is a channel whose open state is dependent on low voltage across the membrane in which it is embedded. GO:0008331 high voltage-gated calcium channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008331 P-type calcium channel|Q-type calcium channel|high voltage-dependent calcium channel activity|high voltage gated calcium channel activity|L-type calcium channel|N-type calcium channel Enables the transmembrane transfer of a calcium ion by a high voltage-gated channel. A high voltage-gated channel is a channel whose open state is dependent on high voltage across the membrane in which it is embedded. GO:0008330 protein tyrosine/threonine phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008330 Catalysis of the reactions: protein threonine phosphate + H2O = protein threonine + phosphate; and protein tyrosine phosphate + H2O = protein tyrosine + phosphate. CHEBI:83586 N(tele)-phosphonato-L-histidine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83586 CHEBI:83585 N(tele)-phospho-L-histidine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83585 CHEBI:83583 1,1',2-trilinoleoyl-2'-palmitoyl cardiolipin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83583 GO:0047949 glutarate-semialdehyde dehydrogenase (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047949 RHEA:12064|EC:1.2.1.20|MetaCyc:GLUTARATE-SEMIALDEHYDE-DEHYDROGENASE-RXN glutarate semialdehyde dehydrogenase (NAD+) activity|glutarate-semialdehyde:NAD+ oxidoreductase activity Catalysis of the reaction: glutarate semialdehyde + NAD+ + H2O = glutarate + NADH. CHEBI:83582 1,1',2-trilinoleoyl-2'-oleoyl cardiolipin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83582 GO:0047948 glutarate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047948 EC:6.2.1.6|RHEA:14169|MetaCyc:GLUTARATE--COA-LIGASE-RXN|KEGG_REACTION:R02402 glutarate:CoA ligase (ADP-forming)|glutaryl-CoA synthetase activity|glutaryl coenzyme A synthetase activity Catalysis of the reaction: ATP + CoA + glutarate = ADP + glutaryl-CoA + H(+) + phosphate. CHEBI:83581 tetralinoleoyl cardiolipin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83581 GO:0047947 glutamine N-phenylacetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047947 MetaCyc:GLUTAMINE-N-PHENYLACETYLTRANSFERASE-RXN|EC:2.3.1.14|RHEA:21844 glutamine phenylacetyltransferase activity|phenylacetyl-CoA:L-glutamine alpha-N-phenylacetyltransferase activity|phenylacetyl-CoA:L-glutamine N-acetyltransferase activity Catalysis of the reaction: phenylacetyl-CoA + L-glutamine = CoA + alpha-N-phenylacetyl-L-glutamine. CHEBI:83580 trilinoleoyl 2-monolysocardiolipin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83580 GO:0047946 glutamine N-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047946 RHEA:18469|MetaCyc:GLUTAMINE-N-ACYLTRANSFERASE-RXN|EC:2.3.1.68 acyl-CoA:L-glutamine N-acyltransferase activity Catalysis of the reaction: acyl-CoA + L-glutamine = CoA + N-acyl-L-glutamine. GO:0047945 L-glutamine:pyruvate aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047945 Reactome:R-HSA-893616|EC:2.6.1.15|KEGG_REACTION:R00576|RHEA:10400|MetaCyc:GLUTAMINE--PYRUVATE-AMINOTRANSFERASE-RXN glutaminase II activity|glutamine-alpha-keto acid transaminase activity|glutamine-keto acid aminotransferase activity|glutamine--oxo-acid transaminase activity|glutamine-alpha-keto acid transamidase activity|glutamine transaminase activity|L-glutamine transaminase L|glutamine--pyruvate aminotransferase activity|gamma-glutaminyltransferase activity|glutamine-pyruvate transaminase activity|glutamine transaminase L activity|glutamine-oxo acid aminotransferase activity Catalysis of the reaction: L-glutamine + pyruvate = 2-oxoglutaramate + L-alanine. GO:0008309 double-stranded DNA exodeoxyribonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008309 double-stranded DNA specific exodeoxyribonuclease activity Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a double-stranded DNA molecule. GO:0008308 voltage-gated anion channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008308 Reactome:R-HSA-9012374 voltage-gated ion-selective channel activity|voltage-dependent ion-selective channel activity Enables the transmembrane transfer of an anion by a voltage-gated channel. An anion is a negatively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. GO:0008307 structural constituent of muscle biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008307 The action of a molecule that contributes to the structural integrity of a muscle fiber. GO:0008306 associative learning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008306 Wikipedia:Learning#Associative_learning conditional learning|classical conditioning|Pavlovian conditioning|conditional response Learning by associating a stimulus (the cause) with a particular outcome (the effect). GO:0008305 integrin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0008305 laminin receptor protein A protein complex that is composed of one alpha subunit and one beta subunit, both of which are members of the integrin superfamily of cell adhesion receptors; the complex spans the plasma membrane and binds to extracellular matrix ligands, cell-surface ligands, and soluble ligands. GO:0008304 obsolete eukaryotic translation initiation factor 4 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0008304 eukaryotic translation initiation factor 4 complex|eIF-4 OBSOLETE. (Was not defined before being made obsolete). GO:0047955 glycerol dehydrogenase (acceptor) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047955 EC:1.1.99.22|KEGG_REACTION:R01045|MetaCyc:GLYCEROL-DEHYDROGENASE-ACCEPTOR-RXN|RHEA:17493 glycerol:(acceptor) 1-oxidoreductase activity|glycerol:acceptor 1-oxidoreductase activity Catalysis of the reaction: A + glycerol = AH(2) + glycerone. GO:0008303 caspase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0008303 cysteine-type endopeptidase complex A protein complex that contains one or more cysteine-type endopeptidases (also called caspases), which give the complex a peptidase activity with specificity for the hydrolysis of aspartyl bonds. These complexes may be involved e.g. in apoptotic or inflammation processes. GO:0047954 glycerol-2-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047954 EC:3.1.3.19|RHEA:13105|MetaCyc:GLYCEROL-2-PHOSPHATASE-RXN|KEGG_REACTION:R01043 glycerol-2-phosphate phosphohydrolase activity|beta-glycerophosphate phosphatase activity|2-glycerophosphatase activity|beta-glycerophosphatase activity Catalysis of the reaction: glycerol 2-phosphate + H(2)O = glycerol + phosphate. GO:0008302 female germline ring canal formation, actin assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008302 ring canal formation, actin assembly|ovarian ring canal formation, actin assembly|nurse cell ring canal formation, actin assembly Recruitment and organization of actin filaments in female germline ring canals. GO:0008301 DNA binding, bending biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008301 DNA bending involving DNA binding|DNA bending activity The activity of binding selectively and non-covalently to and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence. GO:0047953 glycerol 2-dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047953 MetaCyc:GLYCEROL-2-DEHYDROGENASE-NADP+-RXN|KEGG_REACTION:R01039|RHEA:12753|EC:1.1.1.156 dihydroxyacetone (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|dihydroxyacetone reductase activity|glycerol:NADP+ 2-oxidoreductase (glycerone-forming)|DHA oxidoreductase activity|dihydroxyacetone reductase (NADPH) Catalysis of the reaction: glycerol + NADP(+) = glycerone + H(+) + NADPH. GO:0008300 isoprenoid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008300 isoprenoid catabolism|polyterpene catabolism|polyisoprenoid degradation|polyisoprenoid catabolism|polyisoprenoid breakdown|polyisoprenoid catabolic process|polyterpene catabolic process|isoprenoid degradation|isoprenoid breakdown The chemical reactions and pathways resulting in the breakdown of any isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues. GO:0047952 glycerol-3-phosphate dehydrogenase [NAD(P)+] activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047952 KEGG_REACTION:R00844|MetaCyc:GLYC3PDEHYDROGBIOSYN-RXN|EC:1.1.1.94 glycerol-3-phosphate dehydrogenase (NAD(P)+) activity|L-glycerol-3-phosphate:NAD(P) oxidoreductase activity|sn-glycerol-3-phosphate:NAD(P)+ 2-oxidoreductase activity|glycerol phosphate dehydrogenase (nicotinamide adenine dinucleotide (phosphate)) activity Catalysis of the reaction: sn-glycerol 3-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H + H+. GO:0047951 glutathione thiolesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047951 RHEA:22708|KEGG_REACTION:R00547|EC:3.1.2.7|MetaCyc:GLUTATHIONE-THIOESTERASE-RXN citryl-glutathione thioesterhydrolase activity|glutathione thioesterase activity|S-acylglutathione hydrolase activity Catalysis of the reaction: S-acylglutathione + H(2)O = a carboxylate + glutathione + H(+). GO:0047950 glutathione oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047950 EC:1.8.3.3|KEGG_REACTION:R00120|RHEA:24112|MetaCyc:GLUTATHIONE-OXIDASE-RXN glutathione:oxygen oxidoreductase activity Catalysis of the reaction: 2 glutathione + O(2) = glutathione disulfide + H(2)O(2). CHEBI:58596 coenzyme B(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58596 CHEBI:58595 dGDP(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58595 CHEBI:58594 gibberellin A8(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58594 CHEBI:58593 dCDP(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58593 CHEBI:58592 5-amino-1-(5-phosphonato-D-ribosyl)imidazol-3-ium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58592 GO:0047959 glycine dehydrogenase (cytochrome) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047959 RHEA:16909|MetaCyc:GLYCINE-DEHYDROGENASE-CYTOCHROME-RXN|EC:1.4.2.1 glycine-cytochrome c reductase activity|glycine:ferricytochrome-c oxidoreductase (deaminating)|reductase, glycine-cytochrome c Catalysis of the reaction: glycine + H2O + 2 ferricytochrome c = glyoxylate + NH3 + 2 ferrocytochrome c. CHEBI:58591 3-disulfanyl-L-alanine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58591 GO:0047958 glycine:2-oxoglutarate aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047958 MetaCyc:GLYCINE-AMINOTRANSFERASE-RXN|EC:2.6.1.4|RHEA:14089 glyoxylate-glutamic transaminase activity|glycine aminotransferase activity|glycine transaminase activity|glyoxylate-glutamate aminotransferase activity|glutamic-glyoxylic transaminase activity|glutamate-glyoxylate transaminase activity|L-glutamate:glyoxylate aminotransferase activity Catalysis of the reaction: glycine + 2-oxoglutarate = glyoxylate + L-glutamate. GO:0047957 4'-methoxyisoflavone 2'-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047957 EC:1.14.14.89|RHEA:12388|MetaCyc:ISOFLAVONE-2-HYDROXYLASE-RXN formononetin,NADPH:oxygen oxidoreductase (2'-hydroxylating)|isoflavone 2'-monooxygenase activity Catalysis of the reaction: formononetin + NADPH + O2 = 2'-hydroxyformononetin + NADP+ + H2O. CHEBI:58590 gibberellin A3(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58590 GO:0047956 glycerol dehydrogenase [NADP+] activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047956 EC:1.1.1.72|MetaCyc:GLYCEROL-DEHYDROGENASE-NADP+-RXN|RHEA:23592 glycerol dehydrogenase (NADP+) activity|glycerol:NADP+ oxidoreductase activity Catalysis of the reaction: glycerol + NADP+ = D-glyceraldehyde + NADPH. OBO:GOCHE_25212 substance with metabolite role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_25212 CHEBI:58599 N'-phosphonatoguanidinoethyl methyl phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58599 GO:0008319 obsolete prenyl protein specific endopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008319 prenyl protein specific endopeptidase activity OBSOLETE. (Was not defined before being made obsolete). GO:0008318 protein prenyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008318 Catalysis of the covalent addition of an isoprenoid group such as a farnesyl or geranylgeranyl group via thioether linkages to a cysteine residue in a protein. GO:0008317 gurken receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008317 gurken receptor ligand Interacting selectively and non-covalently with the gurken growth factor receptor. GO:0008316 structural constituent of vitelline membrane biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008316 The action of a molecule that contributes to the structural integrity of the vitelline membrane of an egg. An example of this is found in Drosophila melanogaster. GO:0008315 G2/MI transition of meiotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008315 meiotic G2/MI transition|meiotic cell cycle G2/MI phase transition|meiotic G2/MI phase transition The cell cycle process in which a cell progresses from meiotic G2 phase to M phase of meiosis I. GO:0047966 glycosulfatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047966 EC:3.1.6.3|RHEA:19145|MetaCyc:GLYCOSULFATASE-RXN|KEGG_REACTION:R00534 glycosulphatase activity|sugar-sulfate sulfohydrolase activity|glucosulfatase activity Catalysis of the reaction: D-glucose 6-sulfate + H(2)O = D-glucose + H(+) + sulfate. GO:0008314 gurken signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008314 signaling by Gurken|gurken receptor signalling pathway|gurken receptor signaling pathway|gurken-activated signaling pathway The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to the ligand Gurken. GO:0008313 gurken-activated receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008313 gurken receptor activity Combining with the ligand Gurken to initiate a change in cell activity. GO:0047965 glycoprotein O-fatty-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047965 EC:2.3.1.142|MetaCyc:GLYCOPROTEIN-O-FATTY-ACYLTRANSFERASE-RXN protein acyltransferase activity|fatty-acyl-CoA:mucus-glycoprotein fatty-acyltransferase activity Catalysis of the reaction: palmitoyl-CoA + mucus glycoprotein = CoA + O-palmitoylglycoprotein. GO:0047964 glyoxylate reductase (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047964 MetaCyc:GLYCOLATE-REDUCTASE-RXN|EC:1.1.1.26|RHEA:18229 glycolate reductase activity|glyoxylic acid reductase activity|NADH-dependent glyoxylate reductase activity Catalysis of the reaction: glycolate + NAD+ = glyoxylate + NADH. GO:0008312 7S RNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008312 Interacting selectively and non-covalently with 7S RNA, the RNA component of the signal recognition particle (SRP). GO:0047963 glycine N-choloyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047963 RHEA:14001|MetaCyc:GLYCINE-N-CHOLOYLTRANSFERASE-RXN|EC:2.3.1.65 bile acid-CoA:amino acid N-acyltransferase activity|amino acid N-choloyltransferase activity|choloyl-CoA:glycine N-choloyltransferase activity|cholyl-CoA glycine-taurine N-acyltransferase activity|cholyl-CoA:taurine N-acyltransferase activity|BAT activity|BACAT activity|glycine--taurine N-acyltransferase activity Catalysis of the reaction: choloyl-CoA + glycine = CoA + glycocholate. GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008311 double-stranded DNA specific 3'-5' exodeoxyribonuclease activity Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a double-stranded DNA molecule. GO:0047962 glycine N-benzoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047962 RHEA:18493|MetaCyc:GLYCINE-N-BENZOYLTRANSFERASE-RXN|Reactome:R-HSA-159574|EC:2.3.1.71|KEGG_REACTION:R02452|Reactome:R-HSA-159566 benzoyl CoA-amino acid N-acyltransferase activity|benzoyl-CoA:glycine N-benzoyltransferase activity|benzoyl-CoA:glycine N-acyltransferase activity Catalysis of the reaction: benzoyl-CoA + glycine = N-benzoylglycine + CoA + H(+). GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008310 single-stranded DNA specific 3'-5' exodeoxyribonuclease activity|ssDNA-specific 3'-5' exodeoxyribonuclease activity Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a single-stranded DNA molecule. GO:0047961 glycine N-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047961 MetaCyc:GLYCINE-N-ACYLTRANSFERASE-RXN|EC:2.3.1.13|Reactome:R-HSA-2534040|RHEA:19869 glycine-N-acylase activity|glycine acyltransferase activity|acyl-CoA:glycine N-acyltransferase activity Catalysis of the reaction: acyl-CoA + glycine = CoA + N-acylglycine. GO:0047960 glycine dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047960 MetaCyc:GLYCINE-DEHYDROGENASE-RXN|EC:1.4.1.10|RHEA:15721 glycine:NAD+ oxidoreductase (deaminating) Catalysis of the reaction: glycine + H2O + NAD+ = glyoxylate + NH3 + NADH. CHEBI:58585 L-allothreonine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58585 CHEBI:58584 20-hydroxy-leukotriene E4(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58584 CHEBI:58583 4-acetamidobutanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58583 CHEBI:58582 UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58582 CHEBI:58581 precorrin-8X(7-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58581 GO:0047969 glyoxylate oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047969 EC:1.2.3.5|Reactome:R-HSA-389862|MetaCyc:GLYOXYLATE-OXIDASE-RXN|RHEA:14837|KEGG_REACTION:R00466 glyoxylate:oxygen oxidoreductase activity Catalysis of the reaction: glyoxylate + H(2)O + O(2) = H(2)O(2) + H(+) + oxalate. CHEBI:58580 tetrahydrofolyl-poly(glutamate) macromolecule biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58580 GO:0047968 glyoxylate dehydrogenase (acylating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047968 MetaCyc:GLYOXYLATE-DEHYDROGENASE-ACYLATING-RXN|EC:1.2.1.17|KEGG_REACTION:R00468|RHEA:21024 glyoxylate:NADP+ oxidoreductase (CoA-oxalylating) Catalysis of the reaction: CoA + glyoxylate + NADP(+) = H(+) + NADPH + oxalyl-CoA. GO:0047967 glycyrrhizinate beta-glucuronidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047967 RHEA:17369|MetaCyc:GLYCYRRHIZINATE-BETA-GLUCURONIDASE-RXN|EC:3.2.1.128|KEGG_REACTION:R03906 glycyrrhizinate glucuronosylhydrolase activity|glycyrrhizinate b-glucuronidase activity|glycyrrhizin beta-hydrolase activity|glycyrrhizinic acid hydrolase activity|glycyrrhizin hydrolase activity Catalysis of the reaction: glycyrrhizate + H(2)O = 2-(beta-D-glucuronosyl)-D-glucuronate + glycyrrhetinate. CHEBI:58589 pyridoxine 5'-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58589 CHEBI:58588 flavonol oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58588 CHEBI:58587 gibberellin A19(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58587 CHEBI:58586 4-hydroxyphenylglyoxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58586 GO:0047977 hepoxilin-epoxide hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047977 Reactome:R-HSA-2161949|EC:3.3.2.7|RHEA:16665|MetaCyc:HEPOXILIN-EPOXIDE-HYDROLASE-RXN (5Z,9E,14Z)-(8xi,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate hydrolase activity|hepoxilin A3 hydrolase activity|hepoxylin hydrolase activity|hepoxilin A(3) hydrolase activity|hepoxilin epoxide hydrolase activity Catalysis of the reaction: (5Z,9E,14Z)-(8x,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate + H2O = (5Z,9E,14Z)-(8x,11x,12S)-8,11,12-trihydroxyicosa-5,9,14-trienoate. GO:0047976 hamamelose kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047976 KEGG_REACTION:R03766|RHEA:22796|EC:2.7.1.102|MetaCyc:HAMAMELOSE-KINASE-RXN hamamelosekinase (ATP: hamamelose 2'-phosphotransferase)|ATP:D-hamamelose 2'-phosphotransferase activity|ATP/hamamelose 2'-phosphotransferase activity|hamamelose kinase (phosphorylating) Catalysis of the reaction: D-hamamelose + ATP = D-hamamelose 2'-phosphate + ADP + 2 H(+). GO:0047975 guanosine phosphorylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047975 EC:2.4.2.15|RHEA:13233|MetaCyc:GUANPHOSPHOR-RXN guanosine:phosphate alpha-D-ribosyltransferase activity|guanosine:phosphate D-ribosyltransferase activity Catalysis of the reaction: guanosine + phosphate = guanine + D-ribose 1-phosphate. GO:0047974 guanosine deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047974 EC:3.5.4.15|RHEA:12861|MetaCyc:GUANOSINE-DEAMINASE-RXN guanosine aminohydrolase activity|guanosine aminase activity Catalysis of the reaction: guanosine + H2O = xanthosine + NH3. GO:0047973 guanidinoacetate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047973 MetaCyc:GUANIDOACETATE-KINASE-RXN|KEGG_REACTION:R02575|RHEA:14145|EC:2.7.3.1 guanidoacetate kinase activity|ATP:guanidinoacetate N-phosphotransferase activity|glycocyamine kinase activity Catalysis of the reaction: ATP + guanidinoacetate = ADP + 2 H(+) + phosphoguanidinoacetate. GO:0047972 guanidinopropionase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047972 EC:3.5.3.17|MetaCyc:GUANIDINOPROPIONASE-RXN|RHEA:16029|KEGG_REACTION:R00913 3-guanidinopropanoate amidinopropionase activity|GPase activity|GPH Catalysis of the reaction: 3-guanidinopropanoate + H(2)O = beta-alanine + urea. GO:0047971 guanidinobutyrase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047971 EC:3.5.3.7|KEGG_REACTION:R01990|RHEA:19501|MetaCyc:GUANIDINOBUTYRASE-RXN 4-guanidinobutanoate amidinohydrolase activity|GBH|guanidinobutyrate ureahydrolase activity|gamma-guanidobutyrase activity|gamma-guanidinobutyrate amidinohydrolase activity|4-guanidinobutyrate amidinobutyrase activity|G-base activity Catalysis of the reaction: 4-guanidinobutanoate + H(2)O = 4-aminobutanoate + urea. GO:0047970 guanidinoacetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047970 KEGG_REACTION:R00775|RHEA:23268|EC:3.5.3.2|MetaCyc:GUANIDINOACETASE-RXN guanidinoacetate amidinohydrolase activity|glycocyaminase activity Catalysis of the reaction: guanidinoacetate + H(2)O = glycine + urea. CHEBI:58574 4-hydroxybutyryl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58574 CHEBI:58573 kaempferol oxoanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58573 CHEBI:58572 N-[(5S)-5-ammonio-5-carboxylatopentanoyl]-L-cysteinyl-D-valinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58572 CHEBI:58571 5-methylbarbituride biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58571 CHEBI:58570 D-tyrosine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58570 GO:0047979 hexose oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047979 MetaCyc:HEXOSE-OXIDASE-RXN|EC:1.1.3.5 D-hexose:oxygen 1-oxidoreductase activity Catalysis of the reaction: hexose + O2 = aldono-1,5-lactone + H202. GO:0047978 hexadecanol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047978 MetaCyc:HEXADECANOL-DEHYDROGENASE-RXN|RHEA:22056|EC:1.1.1.164 hexadecanol:NAD+ oxidoreductase activity Catalysis of the reaction: hexadecanol + NAD+ = hexadecanal + NADH. CHEBI:58579 beta-D-fructofuranose 2,6-bisphosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58579 CHEBI:58578 UDP-N-acetyl-D-mannosaminouronate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58578 CHEBI:58577 biochanin A 7-O-beta-D-glucoside 6''-O-malonate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58577 CHEBI:58576 2-deoxy-D-ribofuranose 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58576 CHEBI:58575 cob(I)yrinate a,c diamide(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58575 GO:0047980 hippurate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047980 KEGG_REACTION:R01424|RHEA:10424|EC:3.5.1.32|MetaCyc:HIPPURATE-HYDROLASE-RXN N-benzoylamino-acid amidohydrolase activity|benzoylglycine amidohydrolase activity|hippuricase activity Catalysis of the reaction: N-benzoylglycine + H(2)O = benzoate + glycine. GO:0047988 hydroxyacid-oxoacid transhydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047988 Reactome:R-HSA-880002|MetaCyc:HYDROXYACID-OXOACID-TRANSHYDROGENASE-RXN|EC:1.1.99.24|Reactome:R-HSA-880033 (S)-3-hydroxybutanoate:2-oxoglutarate oxidoreductase activity|transhydrogenase, hydroxy acid-oxo acid Catalysis of the reaction: (S)-3-hydroxybutanoate + 2-oxoglutarate = acetoacetate + (R)-2-hydroxyglutarate. GO:0047987 hydroperoxide dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047987 RHEA:25075|MetaCyc:HYDROPEROXIDE-DEHYDRATASE-RXN|EC:4.2.1.92 HPI|(9Z,11E,14Z)-(13S)-hydroperoxyoctadeca-9,11,14-trienoate 12,13-hydro-lyase [(9Z)-(13S)-12,13-epoxyoctadeca-9,11-dienoate-forming]|linoleic acid hydroperoxide isomerase|hydroperoxide isomerase activity|linoleate hydroperoxide isomerase|(9Z,11E,14Z)-(13S)-hydroperoxyoctadeca-9,11,14-trienoate 12,13-hydro-lyase activity Catalysis of the reaction: (9Z,11E,14Z)-(13S)-hydroperoxyoctadeca-9,11,14-trienoate = (9Z)-(13S)-12,13-epoxyoctadeca-9,11-dienoate + H2O. GO:0047986 hydrogen-sulfide S-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047986 EC:2.3.1.10|KEGG_REACTION:R01850|RHEA:16625|MetaCyc:HYDROGEN-SULFIDE-S-ACETYLTRANSFERASE-RXN acetyl-CoA:hydrogen-sulfide S-acetyltransferase activity|hydrogen-sulphide S-acetyltransferase activity|hydrogen-sulfide acetyltransferase activity Catalysis of the reaction: acetyl-CoA + S(2-) = CoA + thioacetate. GO:0047985 hydrogen dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047985 EC:1.12.1.2|MetaCyc:HYDROGEN-DEHYDROGENASE-RXN|RHEA:24636 hydrogenase activity|H(2):NAD(+) oxidoreductase activity|bidirectional hydrogenase activity|hydrogen:NAD+ oxidoreductase activity|NAD-linked hydrogenase activity|H2:NAD+ oxidoreductase activity Catalysis of the reaction: H2 + NAD+ = H+ + NADH. GO:0047984 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0047984 GO:0047983 homoglutathione synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047983 MetaCyc:HOMOGLUTATHIONE-SYNTHASE-RXN|EC:6.3.2.23|KEGG_REACTION:R02741|RHEA:17993 beta-alanine specific hGSH synthetase activity|gamma-L-glutamyl-L-cysteine:beta-alanine ligase (ADP-forming)|homoglutathione synthetase activity Catalysis of the reaction: beta-alanine + L-gamma-glutamyl-L-cysteine + ATP = gamma-L-glutamyl-L-cysteinyl-beta-alanine + ADP + 2 H(+) + phosphate. GO:0047982 homocysteine desulfhydrase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047982 MetaCyc:HOMOCYSTEINE-DESULFHYDRASE-RXN|RHEA:14501|Reactome:R-HSA-1614631|EC:4.4.1.2 homocysteine desulfurase activity|L-homocysteine hydrogen-sulfide-lyase (deaminating; 2-oxobutanoate-forming)|L-homocysteine hydrogen-sulfide-lyase (deaminating) Catalysis of the reaction: L-homocysteine + H2O = sulfide + NH3 + 2-oxobutanoate. GO:0047981 histidine N-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047981 EC:2.3.1.33|RHEA:24596|KEGG_REACTION:R01160|MetaCyc:HISTIDINE-N-ACETYLTRANSFERASE-RXN acetylhistidine synthetase activity|acetyl-CoA:L-histidine N-acetyltransferase activity|histidine acetyltransferase activity Catalysis of the reaction: L-histidine + acetyl-CoA = N(alpha)-acetyl-L-histidine + CoA + H(+). CHEBI:58563 (R)-1-ammoniopropan-2-yl phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58563 CHEBI:58562 all-cis-5,8,11,14,17-icosapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58562 CHEBI:58561 precorrin-3A(7-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58561 CHEBI:58560 L-alpha-glutamyl phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58560 GO:0047989 hydroxybutyrate-dimer hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047989 RHEA:10172|MetaCyc:HYDROXYBUTYRATE-DIMER-HYDROLASE-RXN|EC:3.1.1.22|KEGG_REACTION:R00048 (R)-3-((R)-3-hydroxybutanoyloxy)butanoate hydroxybutanoylhydrolase activity|D-(-)-3-hydroxybutyrate-dimer hydrolase activity Catalysis of the reaction: (R)-3-[(R)-3-hydroxybutanoyloxy]butanoate + H(2)O = 2 (R)-3-hydroxybutanoate + H(+). CHEBI:58567 ajmalinium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58567 CHEBI:58566 D-arabinitol 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58566 PR:000019036 amyloid-beta precursor protein proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000019036 APP/ClvPrd An amyloid-beta precursor protein that has been processed by proteolytic cleavage. CHEBI:58565 5-hydroxyimidazole-4-acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58565 CHEBI:58564 5-amino-1-(5-phosphonato-D-ribosyl)imidazole-4-carboxylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58564 GO:0047991 hydroxylamine oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047991 MetaCyc:HAONITRO-RXN|RHEA:19969|KEGG_REACTION:R00793|EC:1.7.3.6 hydroxylamine:oxygen oxidoreductase activity|HAO|hydroxylamine oxidoreductase Catalysis of the reaction: hydroxylamine + O(2) = H(2)O + H(+) + nitrite. GO:0047990 hydroxyglutamate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047990 KEGG_REACTION:R04135|RHEA:14073|MetaCyc:HYDROXYGLUTAMATE-DECARBOXYLASE-RXN|EC:4.1.1.16 3-hydroxy-L-glutamate 1-carboxy-lyase activity|3-hydroxy-L-glutamate 1-carboxy-lyase (4-amino-3-hydroxybutanoate-forming) Catalysis of the reaction: 3-hydroxy-L-glutamate + H(+) = 4-amino-3-hydroxybutanoate + CO(2). GO:0047999 hyponitrite reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047999 MetaCyc:HYPONITRITE-REDUCTASE-RXN|KEGG_REACTION:R00023|EC:1.7.1.5|RHEA:19337 NADH2:hyponitrite oxidoreductase activity|NADH:hyponitrite oxidoreductase activity|hydroxylamine:NAD+ oxidoreductase activity Catalysis of the reaction: 2 hydroxylamine + 2 NAD(+) = 2 H(+) + hyponitrous acid + 2 NADH. GO:0047998 hyoscyamine (6S)-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047998 KEGG_REACTION:R03812|MetaCyc:HYOSCYAMINE-6-DIOXYGENASE-RXN|EC:1.14.11.11|RHEA:12629 hyoscyamine 6beta-dioxygenase activity|hyoscyamine 6beta-hydroxylase activity|hyoscyamine (6S)-hydroxylase activity|L-hyoscyamine,2-oxoglutarate:oxygen oxidoreductase ((6S)-hydroxylating)|hyoscyamine 6-beta-hydroxylase activity|hyoscyamine 6-hydroxylase activity Catalysis of the reaction: 2-oxoglutarate + L-hyoscyamine + O(2) = (6S)-6-hydroxyhyoscyamine + CO(2) + succinate. GO:0047997 hydroxypyruvate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047997 EC:4.1.1.40|RHEA:20561|KEGG_REACTION:R01393|MetaCyc:HYDROXYPYRUVATE-DECARBOXYLASE-RXN hydroxypyruvate carboxy-lyase (glycolaldehyde-forming)|hydroxypyruvate carboxy-lyase activity Catalysis of the reaction: 3-hydroxypyruvate + H(+) = CO(2) + glycolaldehyde. GO:0047996 hydroxyphytanate oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047996 MetaCyc:HYDROXYPHYTANATE-OXIDASE-RXN|RHEA:21680|KEGG_REACTION:R07151|EC:1.1.3.27 L-2-hydroxyphytanate:oxygen 2-oxidoreductase Catalysis of the reaction: (2S)-2-hydroxyphytanate + O(2) = 2-oxophytanate + H(2)O(2). UBERON:2001431 primitive olfactory epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_2001431 GO:0047995 hydroxyphenylpyruvate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047995 RHEA:10780|MetaCyc:HYDROXYPHENYLPYRUVATE-REDUCTASE-RXN|EC:1.1.1.237 HPRP|4-hydroxyphenyllactate:NAD+ oxidoreductase activity Catalysis of the reaction: 3-(4-hydroxyphenyl)lactate + NAD+ = 3-(4-hydroxyphenyl)pyruvate + NADH. GO:0047994 hydroxymethylglutaryl-CoA hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047994 RHEA:16305|EC:3.1.2.5|KEGG_REACTION:R02083|MetaCyc:HYDROXYMETHYLGLUTARYL-COA-HYDROLASE-RXN (S)-3-hydroxy-3-methylglutaryl-CoA hydrolase activity|hydroxymethylglutaryl coenzyme A hydrolase activity|hydroxymethylglutaryl coenzyme A deacylase activity|3-hydroxy-3-methylglutaryl-CoA hydrolase activity|beta-hydroxy-beta-methylglutaryl coenzyme A hydrolase activity|beta-hydroxy-beta-methylglutaryl coenzyme A deacylase activity Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA + H(2)O = 3-hydroxy-3-methylglutarate + CoA + H(+). GO:0047993 hydroxymalonate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047993 RHEA:11284|EC:1.1.1.167|MetaCyc:HYDROXYMALONATE-DEHYDROGENASE-RXN|KEGG_REACTION:R02969 hydroxymalonate:NAD+ oxidoreductase activity Catalysis of the reaction: hydroxymalonate + NAD(+) = H(+) + NADH + oxomalonate. GO:0047992 hydroxylysine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047992 KEGG_REACTION:R03378|RHEA:19049|EC:2.7.1.81|MetaCyc:HYDROXYLYSINE-KINASE-RXN|Reactome:R-HSA-6788611 hydroxylysine kinase (phosphorylating)|guanosine triphosphate:5-hydroxy-L-lysine O-phosphotransferase activity|GTP:5-hydroxy-L-lysine O-phosphotransferase activity Catalysis of the reaction: erythro-5-hydroxy-L-lysine + GTP = 5-phosphonooxy-L-lysine + GDP + 2 H(+). CHEBI:58552 N(2')-acetylgentamycin C1a(4+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58552 CHEBI:34584 boldenone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_34584 CHEBI:58550 N(1),N(12)-diacetylsperminium(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58550 CHEBI:58558 N-benzyloxycarbonyl-L-leucinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58558 CHEBI:58557 N-acetyl-D-mannosamine 6-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58557 CHEBI:58556 (S)-2-amino-6-oxopimelate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58556 CHEBI:58555 S-acetylphosphopantotheine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58555 CHEBI:58554 gibberellin A44(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58554 CHEBI:58553 5beta,9alpha,10alpha-labda-8(20),13-dien-15-yl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58553 PR:000019005 serum amyloid P-component proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000019005 APCS/ClvPrd A serum amyloid P-component that has been processed by proteolytic cleavage. CHEBI:34596 (3S,5R,6R)-3,5-dihydroxy-6,7-didehydro-5,6-dihydro-12'-apo-beta-caroten-12'-al biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_34596 CHEBI:58541 5-methyldeoxycytidine 5'-diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58541 CHEBI:58540 (Kdo)2-lipid A(6-) (E. coli) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58540 NCBITaxon:1798711 Cyanobacteria/Melainabacteria group organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_1798711 CHEBI:34597 (3S,5R,6S)-5,6-epoxy-3-hydroxy-5,6-dihydro-12'-apo-beta-caroten-12'-al biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_34597 CHEBI:58549 kanamycin B(5+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58549 CHEBI:58548 S-methyl-5-thio-D-ribulose 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58548 PR:000019010 apolipoprotein A-I proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000019010 APOA1/ClvPrd An apolipoprotein A-I that has been processed by proteolytic cleavage. CHEBI:58547 N-hydroxy-L-tyrosinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58547 CHEBI:58546 cyanidin 3-O-rutinoside betaine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58546 CHEBI:58544 3',4',5,7-pentahydroxy-8-methoxyflavon-3-olate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58544 CHEBI:58543 cis-dodec-3-enoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58543 CHEBI:58542 D-arabino-hex-3-ulose 6-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58542 GO:0033361 lysine biosynthetic process via diaminopimelate, dehydrogenase pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033361 MetaCyc:PWY-2942 lysine biosynthesis via diaminopimelic acid, dehydrogenase pathway|lysine formation via diaminopimelate, dehydrogenase pathway|lysine synthesis via diaminopimelate, dehydrogenase pathway|lysine anabolism via diaminopimelate, dehydrogenase pathway The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in a single enzymatic step. GO:0033360 lysine biosynthetic process via diaminopimelate and L-2-acetamido-6-oxoheptanedioate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033360 MetaCyc:PWY-2941 lysine biosynthetic process via diaminopimelic acid and L-2-acetamido-6-oxoheptanedioate|lysine biosynthesis via diaminopimelic acid and L-2-acetamido-6-oxoheptanedioate|lysine formation via diaminopimelate and L-2-acetamido-6-oxoheptanedioate|lysine synthesis via diaminopimelate and L-2-acetamido-6-oxoheptanedioate|lysine anabolism via diaminopimelate and L-2-acetamido-6-oxoheptanedioate The chemical reactions and pathways resulting in the formation of lysine, via the intermediates diaminopimelate and L-2-acetamido-6-oxoheptanedioate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in four enzymatic steps. GO:0033369 establishment of protein localization to mast cell secretory granule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033369 establishment of protein localisation in mast cell secretory granule|establishment of protein localization in mast cell secretory granule The directed movement of a protein to a location within a secretory granule in a mast cell. CHEBI:138067 N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-L-threonine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138067 GO:0033368 protease localization to mast cell secretory granule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033368 protease localization in mast cell secretory granule|protease localisation in mast cell secretory granule Any process in which a protease is transported to, or maintained in, a location within a secretory granule in a mast cell. GO:0033367 protein localization to mast cell secretory granule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033367 protein localisation in mast cell secretory granule|protein localization in mast cell secretory granule A process in which a protein is transported to, or maintained in, a location within a secretory granule in a mast cell. GO:0033366 protein localization to secretory granule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033366 protein localization in secretory granule|protein localisation in secretory granule A process in which a protein is transported to, or maintained in, a location within a secretory granule. GO:0033365 protein localization to organelle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033365 protein localisation to organelle|protein localization in organelle A process in which a protein is transported to, or maintained in, a location within an organelle. GO:0033364 mast cell secretory granule organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033364 mast cell secretory granule organisation|mast cell secretory granule maturation|mast cell secretory granule organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a mast cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. GO:0033363 secretory granule organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033363 secretory granule organization and biogenesis|secretory granule organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. GO:0033362 lysine biosynthetic process via diaminopimelate, diaminopimelate-aminotransferase pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033362 MetaCyc:PWY-5097 lysine formation via diaminopimelate, diaminopimelate-aminotransferase pathway|lysine biosynthesis via diaminopimelate, diaminopimelate-aminotransferase pathway|lysine anabolism via diaminopimelate, diaminopimelate-aminotransferase pathway|lysine synthesis via diaminopimelate, diaminopimelate-aminotransferase pathway The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in two enzymatic steps. CHEBI:138068 ribonucleoside 5'-diphosphate-alpha-D-glucose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138068 GO:0033359 lysine biosynthetic process via diaminopimelate and N-succinyl-2-amino-6-ketopimelate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033359 MetaCyc:DAPLYSINESYN-PWY lysine synthesis via diaminopimelate and N-succinyl-2-amino-6-ketopimelate|lysine formation via diaminopimelate and N-succinyl-2-amino-6-ketopimelate|lysine biosynthetic process via diaminopimelic acid and N-succinyl-2-amino-6-ketopimelate|lysine biosynthesis via diaminopimelic acid and N-succinyl-2-amino-6-ketopimelate|lysine anabolism via diaminopimelate and N-succinyl-2-amino-6-ketopimelate The chemical reactions and pathways resulting in the formation of lysine, via the intermediates diaminopimelate and N-succinyl-2-amino-6-ketopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in four enzymatic steps. GO:0033350 apiose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033350 apiose anabolism|apiose synthesis|apiose formation|apiose biosynthesis The chemical reactions and pathways resulting in the formation of apiose, the branched tetrose 3-C-(hydroxymethyl)-D-glycero-tetrose. CHEBI:138078 5'-(N(2),N(7)-dimethyl 5'-triphosphoguanosine)-(purine ribonucleotide)(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138078 GO:0033358 UDP-L-arabinose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033358 MetaCyc:PWY-63|MetaCyc:PWY-82 UDP-L-arabinose anabolism|UDP-L-arabinose synthesis|UDP-L-arabinose biosynthesis|UDP-L-arabinose formation The chemical reactions and pathways resulting in the formation of UDP-L-arabinose, uridinediphosphoarabinose, a substance composed of arabinose in glycosidic linkage with uridine diphosphate. GO:0033357 L-arabinose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033357 L-arabinose biosynthesis|L-arabinose anabolism|L-arabinose synthesis|L-arabinose formation The chemical reactions and pathways resulting in the formation of L-arabinose, arabino-pentose. CHEBI:138077 chloroxanthin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138077 CHEBI:138076 1,1'-dihydroxyneurosporene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138076 GO:0033356 UDP-L-arabinose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033356 UDP-L-arabinose metabolism The chemical reactions and pathways involving UDP-L-arabinose, uridinediphosphoarabinose, a substance composed of arabinose in glycosidic linkage with uridine diphosphate. CHEBI:138075 5-formyl CMP(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138075 GO:0033355 ascorbate glutathione cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033355 MetaCyc:PWY-2261 hydrogen peroxide detoxification A cyclic series of interconversions involving L-ascorbate and glutathione that scavenges hydrogen peroxide and reduces it to water, with concomitant oxidation of NADPH. GO:0033354 chlorophyll cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033354 MetaCyc:PWY-5068 A cyclic series of interconversions involving chlorophyll a, chlorophyll b and several chlorophyllide intermediates. GO:0033353 S-adenosylmethionine cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033353 MetaCyc:PWY-5041 activated methyl cycle|SAM cycle A cyclic series of interconversions involving S-adenosylmethionine, S-adenosyl-L-homocysteine, L-cysteine, and L-methionine. Couples utilization of the methyl group of SAM with recycling of the homocysteinyl group and regeneration of methionine. GO:0033352 UDP-D-apiose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033352 MetaCyc:PWY-4821|MetaCyc:PWY-5113 UDP-D-apiose anabolism|UDP-D-apiose biosynthesis|UDP-D-apiose synthesis|UDP-D-apiose formation The chemical reactions and pathways resulting in the formation of UDP-D-apiose, uridinediphosphoapicose, a substance composed of apiose in glycosidic linkage with uridine diphosphate. CHEBI:138079 5'-(N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-(purine ribonucleotide)(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138079 GO:0033351 UDP-D-apiose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033351 UDP-D-apiose metabolism The chemical reactions and pathways involving UDP-D-apiose, uridinediphosphoapiose, a substance composed of apiose in glycosidic linkage with uridine diphosphate. CHEBI:138052 (3S)-3,4-dihydroxy-L-proline residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138052 CHEBI:138051 selina-4(15),7(11)-diene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138051 CHEBI:138050 pseudolaratriene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138050 GO:0033349 apiose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033349 apiose metabolism The chemical reactions and pathways involving apiose, the branched tetrose 3-C-(hydroxymethyl)-D-glycero-tetrose. GO:0033348 tetrose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033348 tetrose anabolism|tetrose synthesis|tetrose formation|tetrose biosynthesis The chemical reactions and pathways resulting in the formation of a tetrose, any monosaccharide with a chain of four carbon atoms in the molecule. GO:0008389 coumarin 7-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008389 Reactome:R-HSA-211881|Reactome:R-HSA-76453 cytochrome P450 CYP2A5 Catalysis of the reaction: coumarin + O2 + NADPH + H+ = hydroxycoumarin + H2O + NADP+. GO:0008388 testosterone 15-alpha-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008388 cytochrome P450 CYP2A4 Catalysis of the reaction: testosterone + donor-H2 + O2 = 15-alpha-hydroxytestosterone + H2O. GO:0008387 steroid 7-alpha-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008387 cytochrome P450 CYP2A12 Catalysis of the reaction: a steroid + donor-H2 + O2 = 7-alpha-hydroxysteroid + H2O. GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008386 Reactome:R-HSA-193101|MetaCyc:1.14.15.6-RXN|EC:1.14.15.6|Reactome:R-HSA-193054|RHEA:35739|Reactome:R-HSA-193065 enzymes, cholesterol side-chain-cleaving|cholesterol,reduced-adrenal-ferredoxin:oxygen oxidoreductase (side-chain-cleaving)|cytochrome P-450(scc) activity|cholesterol C20-22 desmolase activity|cytochrome P-450scc|cytochrome p450(scc) activity|cholesterol side-chain-cleaving enzyme activity|C27-side chain cleavage enzyme|cholesterol desmolase activity|steroid 20-22-lyase activity|cholesterol 20-22-desmolase activity|cholesterol C(20-22) desmolase activity|steroid 20-22 desmolase activity|Cyp11a1|cholesterol side-chain cleavage enzyme activity|cytochrome p450scc|desmolase, steroid 20-22 Catalysis of the reaction: cholesterol + reduced adrenal ferredoxin + O2 = pregnenolone + 4-methylpentanal + oxidized adrenal ferredoxin + H2O. GO:0008385 IkappaB kinase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0008385 heterotrimeric IKK complex|IKK complex|trimeric IKK complex A trimeric protein complex that phosphorylates inhibitory-kappaB (I-kappaB) proteins. The complex is composed of two kinase subunits (alpha and beta) and a regulatory gamma subunit (also called NEMO). In a resting state, NF-kappaB dimers are bound to inhibitory IKB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription. GO:0008384 IkappaB kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008384 MetaCyc:2.7.11.10-RXN|EC:2.7.11.10|RHEA:19073|Reactome:R-HSA-5684275|Reactome:R-HSA-5684267 IKBKB|IKBKA|TBK1|inhibitor of NFkappaB kinase activity|IKK-2|IKK-1|ikappaB kinase activity|STK12|IKK|ATP:IkappaB protein phosphotransferase activity|TANK-binding kinase 1 activity|inhibitor of NF-kappaB kinase activity|CHUK Catalysis of the reaction: ATP + IkappaB protein = ADP + IkappaB phosphoprotein. GO:0008394 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008394 GO:0008393 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008393 GO:0008392 arachidonic acid epoxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008392 Reactome:R-HSA-211983 cytochrome P450 CYP2J6|cytochrome P450 CYP2J5 Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to a cis-epoxyeicosatrienoic acid. GO:0008391 arachidonic acid monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008391 cytochrome P450 CYP2B19 Catalysis of the incorporation of one atom from molecular oxygen into arachidonic acid and the reduction of the other atom of oxygen to water. GO:0008390 testosterone 16-alpha-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008390 cytochrome P450 CYP2D11|cytochrome P450 CYP2D10|cytochrome P450 CYP2B10|cytochrome P450 CYP2B9|cytochrome P450 CYP2D9 Catalysis of the reaction: testosterone + donor-H2 + O2 = 16-alpha-hydroxytestosterone + H2O. GO:0033347 tetrose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033347 tetrose metabolism The chemical reactions and pathways involving a tetrose, any monosaccharide with a chain of four carbon atoms in the molecule. CHEBI:138045 (-)-10-epi-cubebol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138045 GO:0033346 asparagine catabolic process via 2-oxosuccinamate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033346 MetaCyc:PWY-4002 The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-oxosuccinamate. CHEBI:138044 (2Z,6E)-hedycaryol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138044 GO:0033345 asparagine catabolic process via L-aspartate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033345 MetaCyc:ASPARAGINE-DEG1-PWY The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate L-aspartate. CHEBI:138043 (2E,6E)-hedycaryol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138043 GO:0033344 cholesterol efflux biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033344 cholesterol export The directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle. CHEBI:138042 tau-cadinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138042 GO:0033343 positive regulation of collagen binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033343 upregulation of collagen binding|stimulation of collagen binding|up-regulation of collagen binding|activation of collagen binding|up regulation of collagen binding Any process that activates or increases the frequency, rate or extent of collagen binding. CHEBI:138049 guaia-4,6-diene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138049 GO:0033342 negative regulation of collagen binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033342 down regulation of collagen binding|inhibition of collagen binding|down-regulation of collagen binding|downregulation of collagen binding Any process that stops, prevents, or reduces the frequency, rate or extent of collagen binding. CHEBI:138048 stellata-2,6,19-triene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138048 GO:0033341 regulation of collagen binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033341 Any process that modulates the frequency, rate or extent of collagen binding. CHEBI:138047 beta-thujene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138047 GO:0033340 pelvic fin development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033340 The process whose specific outcome is the progression of the pelvic fin over time, from its formation to the mature structure. CHEBI:138046 sesterfisherol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138046 CHEBI:138063 coelenterazine h dioxetanone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138063 GO:0033339 pectoral fin development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033339 The process whose specific outcome is the progression of the pectoral fin over time, from its formation to the mature structure. CHEBI:138062 N-terminal N-methyl-L-seryl-L-prolyl-L-lysyl(2+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138062 GO:0033338 medial fin development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033338 median fin development The process whose specific outcome is the progression of a medial fin over time, from its formation to the mature structure. CHEBI:138061 N-terminal L-seryl-L-prolyl-L-lysyl(2+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138061 GO:0033337 dorsal fin development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033337 The process whose specific outcome is the progression of the dorsal fin over time, from its formation to the mature structure. CHEBI:138060 N-terminal N-methyl-L-prolyl-L-prolyl-L-lysyl(2+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138060 GO:0008399 naphthalene hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008399 cytochrome P450 CYP2F2 Catalysis of the conversion of naphthalene to naphthalene 1,2-oxide. GO:0008398 sterol 14-demethylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008398 RHEA:14917|EC:1.14.13.70|Reactome:R-HSA-194678|MetaCyc:1.14.13.70-RXN sterol,NADPH:oxygen oxidoreductase (14-methyl cleaving)|cytochrome P450 CYP51|cytochrome P450 51 activity|lanosterol 14-demethylase activity|lanosterol 14alpha-demethylase activity|obtusufoliol 14-demethylase activity|sterol 14alpha-demethylase activity|lanosterol 14-alpha-demethylase activity|sterol 14-alpha-demethylase activity Catalysis of the reaction: obtusifoliol + 3 O2 + 3 NADPH + 3 H+ = 4-alpha-methyl-5-alpha-ergosta-8,14,24(28)-trien-3-beta-ol + formate + 3 NADP+ + 3 H2O. GO:0008397 sterol 12-alpha-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008397 cytochrome P450 CYP8B1 Catalysis of the reaction: a steroid + donor-H2 + O2 = 12-alpha-hydroxysteroid + H2O. GO:0008396 oxysterol 7-alpha-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008396 Reactome:R-HSA-191972|Reactome:R-HSA-192178|Reactome:R-HSA-5602885|Reactome:R-HSA-192065 cytochrome P450 CYP7B1 Catalysis of the reaction: an oxysterol + NADPH + O2 = 7-alpha-hydroxylated oxysterol + NADP+ + H2O. GO:0008395 steroid hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008395 Reactome:R-HSA-5602170|Reactome:R-HSA-5601849|RHEA:43836|Reactome:R-HSA-193792|Reactome:R-HSA-193143|Reactome:R-HSA-193460|Reactome:R-HSA-193965|Reactome:R-HSA-192042|Reactome:R-HSA-191983|Reactome:R-HSA-192054|Reactome:R-HSA-192123|Reactome:R-HSA-6785244|Reactome:R-HSA-193393|Reactome:R-HSA-193713|Reactome:R-HSA-193737|Reactome:R-HSA-193780|Reactome:R-HSA-191999|Reactome:R-HSA-6785245|Reactome:R-HSA-193497|Reactome:R-HSA-193995|Reactome:R-HSA-193719|Reactome:R-HSA-193060|Reactome:R-HSA-9035960|Reactome:R-HSA-193787 cytochrome P450 CYP2G1|olfactory-specific steroid hydroxylase activity Catalysis of the formation of a hydroxyl group on a steroid by incorporation of oxygen from O2. GO:0033336 caudal fin development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033336 The process whose specific outcome is the progression of the caudal fin over time, from its formation to the mature structure. CHEBI:138056 2,4,5-trihydroxyphenylacetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138056 GO:0033335 anal fin development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033335 The process whose specific outcome is the progression of the anal fin over time, from its formation to the mature structure. CHEBI:138055 2,4,5-trihydroxyphenylacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138055 GO:0033334 fin morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033334 The process in which the anatomical structures of a fin are generated and organized. CHEBI:138054 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138054 CHEBI:138053 5-methoxycarbonylmethoxyuridine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138053 GO:0033333 fin development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033333 The process whose specific outcome is the progression of a fin over time, from its formation to the mature structure. GO:0033332 ent-kaurene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033332 MetaCyc:PWY-5035|MetaCyc:PWY-5032 ent-kaurene biosynthesis|ent-kaurene anabolism|ent-kaurene synthesis|ent-kaurene formation The chemical reactions and pathways resulting in the formation of ent-kaurene. Ent-kaurene is a tetracyclic diterpenoid that is a precursor of several plant isoprenoids, including gibberellins. GO:0033331 ent-kaurene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033331 ent-kaurene metabolism The chemical reactions and pathways involving ent-kaur-16-ene. Ent-kaurene is a tetracyclic diterpenoid that is a precursor of several plant isoprenoids, including gibberellins. CHEBI:138059 N-terminal L-prolyl-L-prolyl-L-lysyl(2+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138059 GO:0033330 kaempferol O-glucoside biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033330 MetaCyc:PWY-5320 kaempferol O-glucoside formation|kaempferol O-glucoside biosynthesis|kaempferol O-glucoside anabolism|kaempferol O-glucoside synthesit The chemical reactions and pathways leading to the formation of O-glucosylated derivatives of kaempferol. CHEBI:138058 N-terminal N-methyl-L-alanyl-L-prolyl-L-lysyl(2+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138058 CHEBI:138057 N-terminal L-alanyl-L-prolyl-L-lysyl(2+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138057 GO:0033329 kaempferol O-glucoside metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033329 kaempferol O-glucoside metabolism The chemical reactions and pathways involving O-glucosylated derivatives of kaempferol. GO:0033328 peroxisome membrane targeting sequence binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033328 mPTS binding|PMP targeting signal binding|peroxisomal membrane protein (PMP) targeting signal (mPTS) binding|PMP targeting signal (mPTS) binding Interacting selectively and non-covalently with a peroxisomal membrane targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome membrane. GO:0033327 Leydig cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033327 The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Leydig cell. A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis. GO:0033326 cerebrospinal fluid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033326 CSF secretion The regulated release of cerebrospinal fluid (CSF) from the choroid plexus of the lateral, third and fourth ventricles. The cerebrospinal fluid is a clear liquid that located within the ventricles, spinal canal, and subarachnoid spaces. GO:0008369 obsolete molecular function biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008369 OBSOLETE. These are terms that have been removed from the active function ontology. GO:0008368 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008368 GO:0008367 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008367 GO:0008366 axon ensheathment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008366 cellular axon ensheathment|nerve ensheathment|cellular nerve ensheathment Any process in which the axon of a neuron is insulated, and that insulation maintained, thereby preventing dispersion of the electrical signal. GO:0008365 adult chitin-based cuticle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008365 adult chitin-based cuticle synthesis|adult chitin-based cuticle formation|adult cuticle anabolism|adult cuticle synthesis|adult chitin-based cuticle biosynthetic process|adult cuticle formation|adult cuticle biosynthetic process|adult chitin-based cuticle anabolism Synthesis and deposition of the chitin-based cuticle of adults following the apolysis of the pupal cuticle. The adult insect cuticle contains cuticullin, a protein epicuticle and a lamellate procuticle. An example of this process is adult chitin-based cuticle development in Drosophila melanogaster. GO:0008364 pupal chitin-based cuticle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008364 pupal cuticle anabolism|pupal cuticle synthesis|pupal cuticle formation Synthesis and deposition of a chitin-based pupal cuticle. At the end of the prepupal period the insect is covered by the pupal cuticle which continues to be elaborated into the pupal period. An example of this is found in Drosophila melanogaster. GO:0008363 larval chitin-based cuticle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008363 larval cuticle biosynthetic process|larval cuticle anabolism|larval cuticle synthesis|larval cuticle formation Synthesis and deposition of a chitin-based larval cuticle. The insect larval cuticle is a secretion from epidermal cells that is shed at each molt. An example of this is found in Drosophila melanogaster. GO:0008362 chitin-based embryonic cuticle biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008362 embryonic cuticle anabolism|embryonic cuticle synthesis|embryonic cuticle formation|embryonic cuticle biosynthetic process Synthesis, including the chemical reactions and pathways resulting in the formation of chitin and other components, and deposition of a chitin-based embryonic cuticle by the underlying epidermal epithelium. This tough, waterproof cuticle layer is essential to provide structural integrity of the larval body. An example of this is found in Drosophila melanogaster. GO:0008372 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008372 GO:0008371 obsolete biological process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008371 OBSOLETE. These are terms that have been removed from the active process ontology. CHEBI:138029 14alpha-methyl steroid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138029 GO:0008370 obsolete cellular component biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0008370 OBSOLETE. These are terms that have been removed from the active component ontology. GO:0033325 choline biosynthetic process via phosphoryl-ethanolamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033325 MetaCyc:PWY-4762|MetaCyc:PWY-3385 choline anabolism via phosphoryl-ethanolamine|choline synthesis via phosphoryl-ethanolamine|choline formation via phosphoryl-ethanolamine|choline biosynthesis via phosphoryl-ethanolamine The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate phosphoryl-ethanolamine. GO:0033324 choline biosynthetic process via N-monomethylethanolamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033324 MetaCyc:PWY-3542|MetaCyc:PWY-4762 choline biosynthesis via N-monomethylethanolamine|choline formation via N-monomethylethanolamine|choline synthesis via N-monomethylethanolamine|choline anabolism via N-monomethylethanolamine The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate N-monomethylethanolamine. GO:0033323 choline biosynthetic process via CDP-choline biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033323 MetaCyc:PWY-4762|MetaCyc:PWY-3561 choline anabolism via CDP-choline|choline synthesis via CDP-choline|choline formation via CDP-choline|choline biosynthesis via CDP-choline The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate CDP-choline. CHEBI:138021 (3S)-3-hydroxy-L-histidine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138021 GO:0033322 homomethionine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033322 MetaCyc:PWY-1186 homomethionine anabolism|homomethionine synthesis|homomethionine biosynthesis|homomethionine formation The chemical reactions and pathways resulting in the formation of homomethionine, a non-protein amino acid synthesized from methionine via chain elongation. CHEBI:138020 alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-1-diphospho-ditrans,polycis-undecaprenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138020 GO:0033321 homomethionine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033321 homomethionine metabolism The chemical reactions and pathways involving homomethionine, a non-protein amino acid synthesized from methionine via chain elongation. CHEBI:138027 N-acetyl-beta-D-galactosaminyl-(1->4)-N-acetyl-beta-D-glucosaminide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138027 GO:0033320 UDP-D-xylose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033320 MetaCyc:PWY-4821 UDP-D-xylose anabolism|UDP-D-xylose biosynthesis|UDP-D-xylose synthesis|UDP-D-xylose formation The chemical reactions and pathways resulting in the formation of UDP-D-xylose, uridinediphosphoxylose, a substance composed of xylose in glycosidic linkage with uridine diphosphate. CHEBI:138026 5alpha-dihydrotestosterone sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138026 CHEBI:138025 N-acetyl-beta-D-glucosaminyl-(1->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138025 CHEBI:138024 alpha-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138024 GO:0033319 UDP-D-xylose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033319 UDP-D-xylose metabolism The chemical reactions and pathways involving UDP-D-xylose, uridinediphosphoxylose, a substance composed of xylose in glycosidic linkage with uridine diphosphate. GO:0033318 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0033318 CHEBI:138041 (+)-4-epi-cubebol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138041 GO:0033317 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0033317 CHEBI:138040 7-epi-alpha-eudesmol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138040 GO:0033316 meiotic spindle assembly checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033316 A cell cycle checkpoint that delays the metaphase/anaphase transition of a meiotic cell cycle until the spindle is correctly assembled and chromosomes are attached to the spindle. GO:0033315 meiotic G2/MI DNA replication checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033315 meiotic cell cycle DNA replication checkpoint A DNA integrity checkpoint that acts to inhibit the G2/M1 transition of the meiotic cell cycle and prevents the initiation of nuclear division until DNA replication is complete. GO:0047900 formate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047900 MetaCyc:FORMATE-KINASE-RXN|RHEA:16009|EC:2.7.2.6|KEGG_REACTION:R00518 ATP:formate phosphotransferase activity Catalysis of the reaction: ATP + formate = ADP + formyl phosphate + H(+). GO:0008379 thioredoxin peroxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008379 Reactome:R-HSA-3697894|RHEA:63528|Reactome:R-HSA-3322995|Reactome:R-HSA-3697882|MetaCyc:RXN0-267|Reactome:R-HSA-2161612|Reactome:R-HSA-3341343 TPx activity|thiol peroxidase activity|TrxPx activity Catalysis of the reaction: thioredoxin + hydrogen peroxide = thioredoxin disulfide + H2O. GO:0008378 galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008378 Reactome:R-HSA-1964501 Catalysis of the transfer of a galactosyl group to an acceptor molecule, typically another carbohydrate or a lipid. CHEBI:83547 N(4)-aminopropylspermidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83547 GO:0008377 light-induced release of internally sequestered calcium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008377 light-induced release of calcium from internal store|light-induced release of internally sequestered calcium ion (Ca2+)|light-induced release of internally stored calcium ion (Ca2+) The process in which the detection of light triggers the release of internally sequestered calcium ions. CHEBI:83546 caldopentamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83546 GO:0008376 acetylgalactosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008376 Reactome:R-HSA-9605700|Reactome:R-HSA-8931648|Reactome:R-HSA-8855954 GalNAc transferase activity Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an oligosaccharide. CHEBI:83545 agmatidine 5'-phosphate(1+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83545 GO:0008375 acetylglucosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008375 Reactome:R-HSA-9683648|Reactome:R-HSA-9694656|Reactome:R-HSA-5694487|Reactome:R-HSA-8879117 GlcNAc transferase activity Catalysis of the transfer of an N-acetylglucosaminyl residue from UDP-N-acetyl-glucosamine to a sugar. GO:0008374 O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008374 Reactome:R-HSA-1482781|Reactome:R-HSA-1482861|Reactome:R-HSA-5483229|Reactome:R-HSA-3238694|Reactome:R-HSA-162683|Reactome:R-HSA-422104|Reactome:R-HSA-422017|Reactome:R-HSA-1482867|Reactome:R-HSA-5358343|Reactome:R-HSA-1482775|Reactome:R-HSA-1482850 Catalysis of the transfer of an acyl group to an oxygen atom on the acceptor molecule. GO:0008373 sialyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008373 Reactome:R-HSA-9697018|Reactome:R-HSA-9694718|Reactome:R-HSA-9683769|Reactome:R-HSA-981814 Catalysis of the transfer of sialic acid to an acceptor molecule, typically the terminal portions of the sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins. GO:0047908 fusarinine-C ornithinesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047908 MetaCyc:FUSARININE-C-ORNITHINESTERASE-RXN|RHEA:20165|EC:3.1.1.48 ornithine esterase activity|N5-acyl-L-ornithine-ester hydrolase activity|5-N-acyl-L-ornithine-ester hydrolase activity Catalysis of the reaction: N5-acyl-L-ornithine ester + H2O = N5-acyl-L-ornithine + an alcohol. GO:0008383 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008383 GO:0008382 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008382 GO:0047907 furylfuramide isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047907 KEGG_REACTION:R04538|MetaCyc:FURYLFURAMIDE-ISOMERASE-RXN|EC:5.2.1.6|RHEA:21848 2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide cis-trans-isomerase activity Catalysis of the reaction: (E)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide = (Z)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide. GO:0008381 mechanosensitive ion channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008381 TC:1.A.23.2.1 mechanically-gated channel activity|mechanically-gated ion channel activity|mechanically gated channel activity Enables the transmembrane transfer of an ion by a channel that opens in response to a mechanical stress. GO:0047906 fucosterol-epoxide lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047906 EC:4.1.2.33|KEGG_REACTION:R03723|RHEA:10884|MetaCyc:FUCOSTEROL-EPOXIDE-LYASE-RXN (24R,24'R)-fucosterol-epoxide acetaldehyde-lyase activity|(24R,24'R)-fucosterol-epoxide acetaldehyde-lyase (desmosterol-forming) Catalysis of the reaction: (24R,24'R)-fucosterol epoxide = acetaldehyde + desmosterol. GO:0047905 fructose-6-phosphate phosphoketolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047905 EC:4.1.2.22|RHEA:12196|MetaCyc:FRUCTOSE-6-PHOSPHATE-PHOSPHOKETOLASE-RXN D-fructose-6-phosphate D-erythrose-4-phosphate-lyase (adding phosphate; acetyl-phosphate-forming)|D-fructose-6-phosphate D-erythrose-4-phosphate-lyase (phosphate-acetylating) activity Catalysis of the reaction: D-fructose 6-phosphate + phosphate = acetyl phosphate + D-erythrose 4-phosphate + H2O. CHEBI:138039 (3E,7E)-dolathalia-3,7,11-triene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138039 GO:0008380 RNA splicing biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0008380 Wikipedia:RNA_splicing pre-mRNA splicing factor activity The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA. CHEBI:2700 anandamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_2700 GO:0047904 fructose 5-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047904 RHEA:22304|KEGG_REACTION:R00873|MetaCyc:FRUCTOSE-5-DEHYDROGENASE-RXN|EC:1.1.99.11 D-fructose:acceptor 5-oxidoreductase activity|fructose 5-dehydrogenase (acceptor)|D-fructose dehydrogenase activity|D-fructose:(acceptor) 5-oxidoreductase activity Catalysis of the reaction: D-fructose + A = 5-dehydro-D-fructose + AH(2). GO:0047903 fructose 5-dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047903 RHEA:14069|EC:1.1.1.124|MetaCyc:FRUCTOSE-5-DEHYDROGENASE-NADP+-RXN D-fructose:NADP+ 5-oxidoreductase activity|5-ketofructose reductase (NADP+) activity|5-ketofructose reductase (NADP(+)) activity|5-keto-D-fructose reductase (NADP+)|D-(-)fructose:(NADP+) 5-oxidoreductase activity|5-ketofructose reductase (NADP)|fructose 5-(nicotinamide adenine dinucleotide phosphate) dehydrogenase activity Catalysis of the reaction: D-fructose + NADP+ = 5-dehydro-D-fructose + NADPH. GO:0047902 formylaspartate deformylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047902 MetaCyc:FORMYLASPARTATE-DEFORMYLASE-RXN|EC:3.5.1.8|RHEA:22040 formylaspartic formylase (formylase I, formylase II)|N-formyl-L-aspartate amidohydrolase activity Catalysis of the reaction: N-formyl-L-aspartate + H2O = formate + L-aspartate. GO:0047901 formyl-CoA hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047901 EC:3.1.2.10|KEGG_REACTION:R00521|RHEA:19741|MetaCyc:FORMYL-COA-HYDROLASE-RXN formyl coenzyme A hydrolase activity Catalysis of the reaction: formyl-CoA + H(2)O = CoA + formate + H(+). CHEBI:138034 dTDP-4-formamido-4,6-dideoxy-alpha-D-glucose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138034 GO:0033314 mitotic DNA replication checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033314 S-phase checkpoint|S-M checkpoint|mitotic cell cycle DNA replication checkpoint|S-M DNA replication checkpoint A cell cycle checkpoint that acts during a mitotic cell cycle and prevents the initiation of mitosis until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome. GO:0033313 meiotic cell cycle checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033313 A cell cycle checkpoint that ensures accurate chromosome replication and segregation by preventing progression through a meiotic cell cycle until conditions are suitable for the cell to proceed to the next stage. GO:0033312 chlorophyll a biosynthetic process via geranylgeranyl-chlorophyll a biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033312 MetaCyc:PWY-5064 chlorophyll a formation via geranylgeranyl-chlorophyll a|chlorophyll a biosynthesis via geranylgeranyl-chlorophyll a|chlorophyll a synthesis via geranylgeranyl-chlorophyll a|chlorophyll a anabolism via geranylgeranyl-chlorophyll a The chemical reactions and pathways leading to the formation of chlorophyll a, via the intermediate geranylgeranyl-chlorophyll a. CHEBI:138032 (3beta,5alpha,17beta)-3-hydroxyandrostan-17-yl sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138032 GO:0033311 chlorophyll a biosynthetic process via phytyl diphosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033311 MetaCyc:PWY-5086 chlorophyll a biosynthetic process via phytyl-PP|chlorophyll a biosynthesis via phytyl diphosphate|chlorophyll a synthesis via phytyl diphosphate|chlorophyll a anabolism via phytyl diphosphate|chlorophyll a formation via phytyl chlorophyll a formation via phytyl-PP The chemical reactions and pathways leading to the formation of chlorophyll a, via the intermediate phytyl diphosphate. CHEBI:138031 Delta(14) steroid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138031 GO:0033310 chlorophyll a catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033310 MetaCyc:PWY-5098|MetaCyc:PWY-5086 chlorophyll a degradation|chlorophyll a breakdown|chlorophyll a catabolism The chemical reactions and pathways leading to the breakdown of chlorophyll a. CHEBI:138037 10-epi-juneol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138037 GO:0047909 galactolipid O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047909 MetaCyc:GALACTOLIPID-O-ACYLTRANSFERASE-RXN|EC:2.3.1.134 mono-beta-D-galactosyldiacylglycerol:mono-beta-D-galactosyldiacylglycerol acyltransferase activity|galactolipid:galactolipid acyltransferase activity Catalysis of the reaction: 2 mono-beta-D-galactosyldiacylglycerol = acylmono-beta-D-galactosyl-diacylglycerol + mono-beta-D-galactosylacylglycerol. CHEBI:138035 S-mycothiol-L-cysteine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138035 GO:0033309 SBF transcription complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033309 SBF complex A protein complex that binds to the Swi4/6 cell cycle box (SCB) promoter element, consensus sequence CRCGAAA, and activates transcription during the G1/S transition of the cell cycle. In Saccharomyces, the complex contains a heterodimer of the DNA binding protein Swi4p and the activator Swi6p, and is associated with additional proteins known as Whi5p and Msa1p. GO:0033308 hydroxyectoine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033308 The directed movement of hydroxyectoine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0033307 phytol salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033307 MetaCyc:PWY-5107 phytol salvage pathway A process that generates phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol, from derivatives of it without de novo synthesis. GO:0033306 phytol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033306 phytol metabolism The chemical reactions and pathways involving phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol. GO:0008349 MAP kinase kinase kinase kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008349 Reactome:R-HSA-177692|Reactome:R-HSA-9645442|Reactome:R-HSA-936991 MAP4K activity|MAPKKKK Catalysis of the phosphorylation of serine and threonine residues in a mitogen-activated protein kinase kinase kinase (MAPKKK), resulting in activation of MAPKKK. MAPKKK signaling pathways relay, amplify and integrate signals from the plasma membrane to the nucleus in response to a diverse range of extracellular stimuli. GO:0033305 chlorophyll a biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033305 chlorophyll a anabolism|chlorophyll a synthesis|chlorophyll a biosynthesis|chlorophyll a formation The chemical reactions and pathways leading to the formation of chlorophyll a. GO:0008348 negative regulation of antimicrobial humoral response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008348 attenuation of antimicrobial humoral response|down regulation of antimicrobial humoral response|inhibition of antimicrobial humoral response|down-regulation of antimicrobial humoral response|downregulation of antimicrobial humoral response Any process that stops, prevents, or reduces the frequency, rate, or extent of an antimicrobial humoral response. GO:0033304 chlorophyll a metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033304 chlorophyll a metabolism The chemical reactions and pathways involving chlorophyll a. GO:0008347 glial cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008347 glia cell migration The orderly movement of a glial cell, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system. GO:0047911 galacturan 1,4-alpha-galacturonidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047911 EC:3.2.1.67|MetaCyc:GALACTURAN-14-ALPHA-GALACTURONIDASE-RXN|RHEA:14117 exopolygalacturonase activity|exo-D-galacturonanase activity|exo-polygalacturonase activity|exo-D-galacturonase activity|galacturan alpha-1,4-galacturonidase activity|poly(1,4-alpha-D-galacturonide) galacturonohydrolase activity|exopoly-D-galacturonase activity|poly(galacturonate) hydrolase activity Catalysis of the reaction: [(1->4)-alpha-D-galacturonide](n) + H2O = [(1->4)-alpha-D-galacturonide](n-1) + D-galacturonate. GO:0047910 galactose 1-dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047910 EC:1.1.1.120|MetaCyc:GALACTOSE-1-DEHYDROGENASE-NADP+-RXN|RHEA:18625 D-galactose dehydrogenase (NADP+)|D-galactose:NADP+ 1-oxidoreductase activity Catalysis of the reaction: D-galactose + NADP+ = D-galactonolactone + NADPH. GO:0008346 larval walking behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008346 larval walking behaviour The behavior of a larval organism relating to the progression of that organism along the ground by the process of lifting and setting down each leg. GO:0008345 larval locomotory behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008345 larval locomotory behaviour Locomotory behavior in a larval (immature) organism. GO:0008344 adult locomotory behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008344 adult locomotory behaviour Locomotory behavior in a fully developed and mature organism. GO:0008343 adult feeding behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008343 adult feeding behaviour Feeding behavior in a fully developed and mature organism. GO:0008342 obsolete larval feeding behavior (sensu Insecta) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008342 larval feeding behavior (sensu Insecta) OBSOLETE. Feeding behavior in an insect larva. GO:0008341 obsolete response to cocaine (sensu Insecta) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008341 response to cocaine (sensu Insecta) OBSOLETE. A change in state or activity of a mature individual as the result of a cocaine stimulus. As in, but not restricted to, the true insects (Insecta, ncbi_taxonomy_id:50557). CHEBI:83554 N(4)-aminopropylspermine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83554 GO:0008340 determination of adult lifespan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008340 The control of viability and duration in the adult phase of the life-cycle. CHEBI:83553 N(4)-bis(aminopropyl)spermidine(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83553 GO:0047919 GDP-mannose 6-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047919 EC:1.1.1.132|RHEA:21728|MetaCyc:GDP-MANNOSE-6-DEHYDROGENASE-RXN|KEGG_REACTION:R00880 GDP-D-mannose:NAD+ 6-oxidoreductase activity|guanosine diphospho-D-mannose dehydrogenase activity|guanosine diphosphomannose dehydrogenase activity|GDP mannose dehydrogenase activity|GDPmannose 6-dehydrogenase activity Catalysis of the reaction: GDP-alpha-D-mannose + H(2)O + 2 NAD(+) = GDP-D-mannuronate + 3 H(+) + 2 NADH. GO:0008350 obsolete kinetochore motor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008350 kinetochore motor activity OBSOLETE. (Was not defined before being made obsolete). GO:0047918 GDP-mannose 3,5-epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047918 MetaCyc:RXN-1882|EC:5.1.3.18|RHEA:11144 guanosine 5'-diphosphate D-mannose:guanosine 5'-diphosphate L-galactose epimerase activity|GDP-D-mannose:GDP-L-galactose epimerase activity|GDPmannose 3,5-epimerase activity Catalysis of the reaction: GDP-mannose = GDP-L-galactose. CHEBI:83550 1,2-ditetradecanoyl-sn-glycerol-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83550 CHEBI:138007 N-acetyl-alpha-D-hexosamine 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138007 GO:0047917 GDP-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047917 KEGG_REACTION:R00337|MetaCyc:GDP-GLUCOSIDASE-RXN|EC:3.2.1.42|RHEA:15049 GDPglucosidase activity|guanosine diphosphate D-glucose glucohydrolase activity|GDPglucose glucohydrolase activity|GDP-glucose glucohydrolase activity|guanosine diphosphoglucosidase activity Catalysis of the reaction: GDP-D-glucose + H(2)O = D-glucose + GDP + H(+). GO:0047916 GDP-6-deoxy-D-talose 4-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047916 EC:1.1.1.135|MetaCyc:GDP-6-DEOXY-D-TALOSE-4-DEHYDROGENASE-RXN guanosine diphospho-6-deoxy-D-talose dehydrogenase activity|GDP-6-deoxy-D-talose:NAD(P)+ 4-oxidoreductase activity Catalysis of the reaction: GDP-6-deoxy-D-talose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-talose + NAD(P)H + H+. GO:0047915 ganglioside galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047915 EC:2.4.1.62|RHEA:16773|MetaCyc:GANGLIOSIDE-GALACTOSYLTRANSFERASE-RXN uridine diphosphogalactose-GM2 galactosyltransferase activity|UDP galactose-LAC Tet-ceramide alpha-galactosyltransferase activity|GM1-synthase activity|UDP-galactose-GM2 ganglioside galactosyltransferase activity|uridine diphosphate D-galactose:glycolipid galactosyltransferase activity|UDP-galactose:N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine beta-1,3-D-galactosyltransferase activity|UDP-galactose-GM2 galactosyltransferase activity|uridine diphosphogalactose-ceramide galactosyltransferase activity|UDP-galactose:N-acetylgalactosaminyl-(N-acetylneuraminyl) galactosyl-glucosyl-ceramide galactosyltransferase activity|UDPgalactose-ceramide galactosyltransferase activity|UDPgalactose:N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine beta-1,3-D-galactosyltransferase activity Catalysis of the reaction: UDP-galactose + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine = UDP + D-galactosyl-1,3-beta-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine. GO:0047914 gamma-glutamylhistamine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047914 EC:6.3.2.18|MetaCyc:GAMMA-GLUTAMYLHISTAMINE-SYNTHASE-RXN|RHEA:18881 g-glutamylhistamine synthase activity|gamma-GHA synthetase activity|L-glutamate:histamine ligase activity|gamma-glutaminylhistamine synthetase activity Catalysis of the reaction: histamine + L-glutamate + ATP = N(alpha)-gamma-L-glutamylhistamine + products of ATP breakdown. GO:0047913 gallate 1-beta-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047913 MetaCyc:GALLATE-1-BETA-GLUCOSYLTRANSFERASE-RXN|RHEA:15249|KEGG_REACTION:R03297|EC:2.4.1.136 gallate 1-b-glucosyltransferase activity|UDP-glucose:gallate beta-D-glucosyltransferase activity|UDPglucose:vanillate 1-O-glucosyltransferase activity|UDP-glucose-vanillate 1-glucosyltransferase activity|UDPglucose:gallate glucosyltransferase activity|UDPglucose:gallate beta-D-glucosyltransferase activity|UDPglucose-vanillate 1-glucosyltransferase activity Catalysis of the reaction: gallate + UDP-D-glucose = 1-O-galloyl-beta-D-glucose + UDP. GO:0047912 galacturonokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047912 MetaCyc:GALACTURONOKINASE-RXN|RHEA:12965|EC:2.7.1.44|KEGG_REACTION:R01980 ATP:D-galacturonate 1-phosphotransferase activity|galacturonokinase (phosphorylating) D-galacturonic acid kinase activity Catalysis of the reaction: alpha-D-galacturonate + ATP = 1-phospho-alpha-D-galacturonate + ADP + 2 H(+). GO:0033303 quercetin O-glucoside biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033303 MetaCyc:PWY-5321 quercetin O-glucoside anabolism|quercetin O-glucoside biosynthesis|quercetin O-glucoside synthesit|quercetin O-glucoside formation The chemical reactions and pathways leading to the formation of O-glucosylated derivatives of quercetin. GO:0033302 quercetin O-glucoside metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033302 quercetin O-glucoside metabolism The chemical reactions and pathways involving O-glucosylated derivatives of quercetin. CHEBI:138000 3-(1-methylpyrrolidin-2-yl)pyridine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138000 GO:0033301 cell cycle comprising mitosis without cytokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033301 A mitotic cell cycle in which mitosis is completed but cytokinesis does not occur, resulting in a cell containing multiple nuclei each with a chromosomal complement of the original ploidy (usually 2N). GO:0033300 dehydroascorbic acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033300 RHEA:60380|Reactome:R-HSA-198818 dehydroascorbic acid transporter activity|dehydroascorbate transporter activity Enables the transfer of dehydroascorbate, 5-(1,2-dihydroxyethyl)furan-2,3,4(5H)-trione, from one side of a membrane to the other. GO:0008359 regulation of bicoid mRNA localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008359 regulation of bicoid mRNA localisation Any process that modulates the frequency, rate or extent of the process in which bicoid mRNA is transported to, or maintained in, a specific location. GO:0008358 maternal determination of anterior/posterior axis, embryo biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008358 The specification of the anterior/posterior axis of the embryo by gradients of maternally-transcribed gene products; exemplified in insects by the morphogens, bicoid and nanos. GO:0047922 gentisate 1,2-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047922 RHEA:18237|EC:1.13.11.4|MetaCyc:GENTISATE-12-DIOXYGENASE-RXN|KEGG_REACTION:R02656 gentisate oxygenase activity|2,5-dihydroxybenzoate dioxygenase activity|gentisate:oxygen 1,2-oxidoreductase (decyclizing)|gentisic acid oxidase activity|gentisate dioxygenase activity Catalysis of the reaction: 2,5-dihydroxybenzoate + O(2) = 3-maleylpyruvate + H(+). GO:0047921 aminoglycoside 2'-N-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047921 KEGG_REACTION:R03056|MetaCyc:GENTAMICIN-2-N-ACETYLTRANSFERASE-RXN|EC:2.3.1.59|RHEA:24516 gentamycin 2'-N-acetyltransferase activity|acetyl-CoA:gentamycin-C1a N2'-acetyltransferase activity|gentamicin acetyltransferase II activity|gentamicin 2'-N-acetyltransferase activity|gentamycin acetyltransferase II|acetyl-CoA:gentamicin-C1a N2'-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + gentamicin C(1a) = N(2')-acetylgentamicin C(1a) + CoA + H(+). This is acetylation of the 2'-amino group of the 6-deoxy-6-aminoglucose ring. GO:0008357 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008357 GO:0008356 asymmetric cell division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008356 Wikipedia:Asymmetric_cell_division asymmetrical cytokinesis|asymmetrical cell division|asymmetric cytokinesis The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity. GO:0047920 geissoschizine dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047920 RHEA:11376|KEGG_REACTION:R03860|EC:1.3.1.36|MetaCyc:GEISSOSCHIZINE-DEHYDROGENASE-RXN geissoschizine:NADP+ 4,21-oxidoreductase activity Catalysis of the reaction: geissoschizine + NADP(+) = 4,21-dehydrogeissoschizine + H(+) + NADPH. GO:0008355 olfactory learning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008355 Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue. GO:0008354 germ cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008354 primordial germ cell migration|germ-cell migration The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form. GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008353 Reactome:R-HSA-170706|MetaCyc:RNA-POLYMERASE-SUBUNIT-KINASE-RXN|RHEA:10216|Reactome:R-HSA-167191|EC:2.7.11.23|Reactome:R-HSA-170704 STK9|RNA-polymerase-subunit kinase activity|RNA polymerase subunit kinase activity|ATP:DNA-directed RNA polymerase phosphotransferase activity|[RNA-polymerase]-subunit kinase activity|CTD kinase activity|RNA polymerase II carboxy-terminal domain kinase activity Catalysis of the reaction: ATP + (DNA-directed RNA polymerase II) = ADP + phospho-(DNA-directed RNA polymerase II); phosphorylation occurs on residues in the carboxy-terminal domain (CTD) repeats. GO:0008352 katanin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0008352 A complex possessing an activity that couples ATP hydrolysis to the severing of microtubules; usually a heterodimer comprising a catalytic subunit (often 60kDa) and a regulatory subunit (often 80 kDa). CHEBI:83565 (trifluoromethyl)benzenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83565 CHEBI:83564 (R)-3-phosphomevalonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83564 GO:0008351 obsolete microtubule severing activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008351 microtubule severing activity OBSOLETE. (Was not defined before being made obsolete). GO:0008361 regulation of cell size biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008361 cell size control Any process that modulates the size of a cell. CHEBI:83563 long-chain alkane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83563 GO:0047929 gluconate dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047929 RHEA:21612|MetaCyc:GLUCONATE-DEHYDRATASE-RXN|EC:4.2.1.39|KEGG_REACTION:R01538 D-gluconate hydro-lyase (2-dehydro-3-deoxy-D-gluconate-forming)|D-gluconate dehydratase activity|D-gluconate hydro-lyase activity Catalysis of the reaction: D-gluconate = 2-dehydro-3-deoxy-D-gluconate + H(2)O. CHEBI:138019 N(6)-propanoyl-L-lysine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138019 CHEBI:83562 N-terminal L-arginyl-L-alpha-amino acid(2+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83562 GO:0008360 regulation of cell shape biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008360 Any process that modulates the surface configuration of a cell. GO:0047928 gibberellin beta-D-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047928 RHEA:20025|EC:2.4.1.176|MetaCyc:GIBBERELLIN-BETA-GLUCOSYLTRANSFERASE-RXN UDP-glucose:gibberellin 2-O-beta-D-glucosyltransferase activity|gibberellin b-glucosyltransferase activity|uridine diphosphoglucose-gibberellate 3-O-glucosyltransferase activity|uridine diphosphoglucose-gibberellate 7-glucosyltransferase activity|UDPglucose:gibberellin 2-O-beta-D-glucosyltransferase activity Catalysis of the reaction: UDP-glucose + gibberellin = UDP + gibberellin 2-O-beta-D-glucoside. CHEBI:83561 N-terminal L-phenylalanyl-L-alpha-amino acid(1+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83561 GO:0047927 gibberellin-44 dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047927 RHEA:16033|EC:1.14.11.12|MetaCyc:RXN1F-168 (gibberellin-44), 2-oxoglutarate:oxygen oxidoreductase activity|oxygenase, gibberellin A44 oxidase activity|(gibberellin-44),2-oxoglutarate:oxygen oxidoreductase activity|gibberellin A44 oxidase activity Catalysis of the reaction: gibberellin 44 + 2-oxoglutarate + O2 = gibberellin 19 + succinate + CO2. GO:0047926 geranyl-diphosphate cyclase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047926 KEGG_REACTION:R02007|EC:5.5.1.8|RHEA:18209|MetaCyc:GERANYL-DIPHOSPHATE-CYCLASE-RXN bornyl diphosphate synthase activity|bornyl pyrophosphate synthase activity|(+)-bornylpyrophosphate cyclase activity|bornyl pyrophosphate synthetase activity|(+)-bornyl-diphosphate lyase (decyclizing) Catalysis of the reaction: geranyl diphosphate = (2S)-bornyl diphosphate. GO:0047925 geranoyl-CoA carboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047925 UM-BBD_reactionID:r1166|RHEA:17701|EC:6.4.1.5|KEGG_REACTION:R03494|MetaCyc:GERANOYL-COA-CARBOXYLASE-RXN geranyl-CoA carboxylase activity|geranoyl coenzyme A carboxylase activity|geranoyl-CoA:carbon-dioxide ligase (ADP-forming) Catalysis of the reaction: ATP + bicarbonate + geranoyl-CoA = 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + ADP + 2 H(+) + phosphate. GO:0047924 geraniol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047924 RHEA:14521|UM-BBD_reactionID:r1163|EC:1.1.1.183|MetaCyc:GERANIOL-DEHYDROGENASE-RXN geraniol:NADP+ oxidoreductase activity Catalysis of the reaction: geraniol + NADP+ = geranial + NADPH. GO:0047923 gentisate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047923 KEGG_REACTION:R02489|RHEA:21312|EC:4.1.1.62|MetaCyc:GENTISATE-DECARBOXYLASE-RXN 2,5-dihydroxybenzoate carboxy-lyase (hydroquinone-forming)|2,5-dihydroxybenzoate decarboxylase activity|gentisate carboxy-lyase activity Catalysis of the reaction: 2,5-dihydroxybenzoate + H(+) = CO(2) + hydroquinone. CHEBI:138011 6-(alpha-D-glucose-1-phospho)-alpha-D-mannoside(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138011 CHEBI:138015 endocrine disruptor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138015 CHEBI:10502 dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_10502 CHEBI:2716 anethole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_2716 CHEBI:2719 Ile(5)-angiotensin II biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_2719 CHEBI:2710 androst-5-ene-3beta,17beta-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_2710 CHEBI:10525 dTDP-beta-L-mycarose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_10525 GO:0033295 hydroxyectoine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033295 Interacting selectively and non-covalently with hydroxyectoine. GO:0033294 ectoine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033294 Interacting selectively and non-covalently with ectoine, 1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid. GO:0033293 monocarboxylic acid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033293 Interacting selectively and non-covalently with a monocarboxylic acid, any organic acid containing one carboxyl (COOH) group or anion (COO-). GO:0033292 T-tubule organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033292 T-tubule organization and biogenesis|T-tubule organisation|transverse tubule organization A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of the T-tubule. A T-tubule is an invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. GO:0033291 eukaryotic 80S initiation complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033291 A protein complex composed of the large and small ribosomal subunits, methionyl-initiatior tRNA, and the capped mRNA. The initiator tRNA is positioned at the ribosomal P site at the AUG codon corresponding to the beginning of the coding region. GO:0033290 eukaryotic 48S preinitiation complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033290 eukaryotic 48S pre-initiation complex|eukaryotic 48S initiation complex A protein complex composed of the small ribosomal subunit, eIF3, eIF1A, methionyl-initiatior methionine and a capped mRNA. The complex is initially positioned at the 5'-end of the capped mRNA. GO:0033299 secretion of lysosomal enzymes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033299 The controlled release of lysosomal enzymes by a cell. GO:0033298 contractile vacuole organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033298 contractile vacuole organisation|contractile vacuole organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a contractile vacuole. A specialized vacuole that fills with water from the cytoplasm and then discharges this externally by the opening of contractile vacuole pores. GO:0033297 ATPase-coupled rhamnose transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033297 ATP-dependent rhamnose transmembrane transporter activity|rhamnose-transporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + rhamnose(out/in) = ADP + phosphate + rhamnose(in/out). GO:0033296 rhamnose binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033296 Interacting selectively and non-covalently with the D- or L-enantiomer of rhamnose. GO:0033284 ATPase-coupled carboxylic acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033284 ATP-dependent carboxylic acid transporter activity|carboxylic acid-transporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carboxylic acid(out/in) = ADP + phosphate + carboxylic acid(in/out). GO:0033283 ATPase-coupled organic acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033283 organic acid-transporting ATPase activity|ATP-dependent organic acid transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + organic acid(out/in) = ADP + phosphate + organic acid(in/out). GO:0033282 protein C inhibitor-acrosin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033282 plasma serine protease inhibitor-acrosin complex|serpin A5-acrosin complex|PCI-acrosin complex|PCI-ACR complex|SERPINA5-acrosin complex A heterodimeric protein complex of protein C inhibitor (SERPINA5) and acrosin; formation of the complex inhibits the protease activity of acrosin. GO:0033281 TAT protein transport complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033281 TAT protein translocation system complex|Twin-arginine translocation complex|TAT protein secretion complex A complex of three proteins integral to the cytoplasmic membrane of bacteria and membranes of organelles derived from bacteria (chloroplasts and mitochondria) involved in membrane transport of folded proteins. GO:0033280 response to vitamin D biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033280 response to calciferol|response to cholecalciferol|response to ergocalciferol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus. GO:0033289 intraconoid microtubule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033289 A microtubule located such that it threads through the conoid and projects through the polar ring. GO:0033288 ATPase-coupled hydroxyectoine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033288 ATP-dependent hydroxyectoine transmembrane transporter activity|hydroxyectoine-transporting ATPase activity|hydroxyectoine transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + hydroxyectoine(out/in) = ADP + phosphate + hydroxyectoine(in/out). GO:0033287 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0033287 GO:0033286 ATPase-coupled ectoine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033286 RHEA:32787 ectoine-transporting ATPase activity|ectoine transmembrane transporter activity|ATP-dependent ectoine transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ectoine(out/in) = ADP + phosphate + ectoine(in/out). GO:0033285 ATPase-coupled monocarboxylic acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033285 ATP-dependent monocarboxylic acid transmembrane transporter activity|monocarboxylic acid-transporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + monocarboxylic acid(out/in) = ADP + phosphate + monocarboxylic acid(in/out). UBERON:3010200 vasculature of respiratory integument biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_3010200 Blood vessels in respiratory skin. GO:0033273 response to vitamin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033273 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus. GO:0033272 myo-inositol hexakisphosphate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033272 phytate transport The directed movement of myo-inositol hexakisphosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0033271 myo-inositol phosphate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033271 The directed movement of any phosphorylated myo-inositol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0033270 paranode region of axon biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033270 NIF_Subcellular:sao234066064|NIF_Subcellular:sao936144858 paranode An axon part that is located adjacent to the nodes of Ranvier and surrounded by lateral loop portions of myelin sheath. GO:0033279 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0033279 GO:0033278 cell proliferation in midbrain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033278 cell proliferation in mesencephalon|mesencepahalic cell proliferation The multiplication or reproduction of cells, resulting in the expansion of a cell population in the midbrain. GO:0033277 abortive mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033277 abortive mitosis A cell cycle in which mitosis is begun and progresses normally through the end of anaphase, but not completed, resulting in a cell with increased ploidy. GO:0033276 transcription factor TFTC complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033276 A protein complex that does not contain either a TATA-binding protein (TBP) or a TBP-like factor, but is composed of several TAFIIs and other proteins, including a histone acetyltransferase. This complex is able to nucleate transcription initiation by RNA polymerase II, can mediate transcriptional activation, and has histone acetyltransferase activity. GO:0033275 actin-myosin filament sliding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033275 actin filament sliding The sliding movement of actin thin filaments and myosin thick filaments past each other. GO:0033274 response to vitamin B2 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033274 response to riboflavin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B2 stimulus. CHEBI:138092 1-[(Z)-alk-1-enyl]-sn-glycero-3-phospho-(N-acyl)ethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138092 CHEBI:138096 1-(1Z-octadecenyl)-sn-glycero-3-phospho-(N-arachidonoyl)ethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138096 CHEBI:138095 1-(1Z-octadecenyl)-sn-glycero-3-phospho-(N-oleoyl)ethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138095 CHEBI:138094 1-(1Z-octadecenyl)-sn-glycero-3-phospho-(N-hexadecanoyl)ethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138094 CHEBI:138093 N-acyl-aromatic L-alpha-amino-acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138093 GO:0033262 regulation of nuclear cell cycle DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033262 regulation of DNA replication involved in S-phase|regulation of DNA replication during S phase|regulation of DNA replication involved in S phase Any process that modulates the frequency, rate or extent of The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle. GO:0033261 obsolete regulation of S phase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033261 MetaCyc:SALVADEHYPOX-PWY|MetaCyc:PWY-5043|MetaCyc:SALVPURINE2-PWY regulation of S phase|regulation of S-phase|regulation of progression through S phase OBSOLETE. A cell cycle process that modulates the rate or extent of the progression through the S phase of the cell cycle. GO:0033260 nuclear DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033260 DNA replication during S phase|DNA replication involved in S phase|nuclear cell cycle DNA replication|DNA replication involved in S-phase The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle. CHEBI:138088 long chain primary alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138088 GO:0033269 internode region of axon biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033269 NIF_Subcellular:sao206157942 internode An axon part that is located between the nodes of Ranvier and surrounded by compact myelin sheath. GO:0033268 node of Ranvier biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033268 NIF_Subcellular:birnlex_1152_2|Wikipedia:Nodes_of_Ranvier node of Ranvier axon An axon part that is a gap in the myelin where voltage-gated sodium channels cluster and saltatory conduction is executed. CHEBI:138087 O-acyl-ADP-D-ribose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138087 GO:0033267 obsolete axon part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0033267 NIF_Subcellular:sao280355188 OBSOLETE. A part of an axon, a cell projection of a neuron. GO:0033266 ABC-type choline transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033266 choline-transporting ATPase activity|ABC-type choline transmembrane transporter activity|ATPase-coupled choline transmembrane transporter activity|ATP-dependent choline transmembrane transporter activity Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of choline across a membrane. GO:0033265 choline binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033265 Interacting selectively and non-covalently with choline, the amine 2-hydroxy-N,N,N-trimethylethanaminium. GO:0033264 obsolete bontoxilysin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033264 bontoxilysin activity|BoNT|botulinum neurotoxin activity OBSOLETE. Catalysis of limited hydrolysis of proteins of the neuroexocytosis apparatus, synaptobrevins, SNAP25 or syntaxin. No detected action on small molecule substrates. GO:0033263 CORVET complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033263 A multimeric protein complex that acts as an endosomal tethering complex (CORVET = class C core vacuole/endosome tethering) by cooperating with Rab GTPases to capture endosomal vesicles and trap them prior to the action of SNAREs; the complex is involved in endo-lysosomal biogenesis and required for transport between endosome and vacuole. The Saccharomyces cerevisiae complex contains Vps8p, Vps3p, Pep5p, Vps16p, Pep3p, and Vps33p. GO:0033251 cephalosporinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033251 MetaCyc:BETA-LACTAMASE-RXN Catalysis of the reaction: a cephalosporin + H2O = a substituted beta-amino acid derivative of the cephalosporin. CHEBI:2762 antimycin A biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_2762 GO:0033250 penicillinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033250 MetaCyc:BETA-LACTAMASE-RXN Catalysis of the reaction: a penicillin + H2O = a substituted beta-amino acid derivative of the penicillin. GO:0033259 plastid DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033259 plastid DNA synthesis|replication of plastid DNA The process in which new strands of DNA are synthesized in a plastid. GO:0033258 plastid DNA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033258 plastid DNA metabolism The chemical reactions and pathways involving plastid DNA. CHEBI:138099 2-[(9S,11R)-epidioxy-(15S)-hydroxy-(5Z,13E)-prostadienoyl]-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138099 CHEBI:138098 2-[(9S,11R)-epidioxy-(15S)-hydroperoxy-(5Z,13E)-prostadienoyl]-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138098 GO:0033257 Bcl3/NF-kappaB2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033257 Bcl3-NFKB2 complex|Bcl3-p52 complex A protein complex containing one Bcl protein and one or more copies of NF-kappaB2; formation of complexes of different stoichiometry depends on the Bcl3:NF-kappaB2 ratio, and allow Bcl3 to exert different regulatory effects on NF-kappaB2-dependent transcription. GO:0033256 I-kappaB/NF-kappaB complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0033256 A protein complex containing an inhibitory-kappaB (I-kappaB/IKB) protein and one or more copies of an NF-kappaB protein. In the resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm. CHEBI:138097 1-(1Z-octadecenyl)-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138097 GO:0033255 SAS acetyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033255 SAS-I complex A protein complex that possesses histone acetyltransferase activity and links histone acetylation to the assembly of transcriptionally silent chromatin. In vitro, the complex acetylates lysine 16 of histone H4 and lysine 14 of histone H3, although the latter may not be relevant in vivo. The complex contains a catalytic subunit and at least two other subunits; in Saccharomyces, the catalytic subunit is Sas2p and additional subunits are Sas4p and Sas5p. GO:0033254 vacuolar transporter chaperone complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033254 VTC complex A protein complex that contains four related proteins that have been implicated in several membrane-related processes, such as sorting of H+-translocating ATPases, endocytosis, ER-Golgi trafficking, vacuole fusion, vacuolar polyphosphate homeostasis and the microautophagic scission of vesicles into the vacuolar lumen. The complex is enriched at the vacuolar membrane, but also found in other cellular compartments, including the ER and the cell periphery. In Saccharomyces, the subunits are Vtc1p, Vtc2p, Vtc3p and Vtc4p. GO:0033253 regulation of penicillinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033253 Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of a penicillin to yield a substituted beta-amino acid derivative. GO:0033252 regulation of beta-lactamase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033252 Any process that modulates the frequency, rate or extent of beta-lactamase activity, the hydrolysis of a beta-lactam to yield a substituted beta-amino acid. GO:0047892 flavone apiosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047892 EC:2.4.2.25|MetaCyc:FLAVONE-APIOSYLTRANSFERASE-RXN|RHEA:19153 UDP-apiose:7-O-(beta-D-glucosyl)-flavone apiosyltransferase activity|uridine diphosphoapiose-flavone apiosyltransferase activity|UDP-apiose:5,4'-dihydroxyflavone 7-O-beta-D-glucoside 2''-O-beta-D-apiofuranosyltransferase activity Catalysis of the reaction: UDP-apiose + 7-O-beta-D-glucosyl-5,7,4'-trihydroxyflavone = UDP + 7-O-(beta-D-apiofuranosyl-1,2-beta-D-glucosyl)-5,7,4'-trihydroxyflavone. GO:0047891 flavone 7-O-beta-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047891 EC:2.4.1.81|RHEA:19577|MetaCyc:FLAVONE-7-O-BETA-GLUCOSYLTRANSFERASE-RXN UDP-glucose-apigenin beta-glucosyltransferase activity|UDPglucose:5,7,3',4'-tetrahydroxyflavone 7-O-beta-D-glucosyltransferase activity|UDPglucose-luteolin beta-D-glucosyltransferase activity|uridine diphosphoglucose-apigenin 7-O-glucosyltransferase activity|UDP-glucose:5,7,3',4'-tetrahydroxyflavone 7-O-beta-D-glucosyltransferase activity|UDPglucose-apigenin beta-glucosyltransferase activity|flavone 7-O-b-glucosyltransferase activity|UDP-glucose-luteolin beta-D-glucosyltransferase activity|uridine diphosphoglucose-luteolin glucosyltransferase activity Catalysis of the reaction: UDP-glucose + 5,7,3',4'-tetrahydroxyflavone = UDP + 7-O-beta-D-glucosyl-5,7,3',4'-tetrahydroxyflavone. GO:0047890 flavanone 4-reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047890 RHEA:11228|EC:1.1.1.234|MetaCyc:FLAVANONE-4-REDUCTASE-RXN (2S)-flavan-4-ol:NADP+ 4-oxidoreductase activity|flavonone 4-reductase activity Catalysis of the reaction: (2S)-flavan-4-ol + NADP+ = (2S)-flavanone + NADPH. CHEBI:58539 L-dehydroascorbate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58539 GO:0047899 formate dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047899 MetaCyc:FORMATE-DEHYDROGENASE-NADP+-RXN|KEGG_REACTION:R00134|EC:1.17.1.10|RHEA:12000 NADP-dependent formate dehydrogenase activity|formate:NADP+ oxidoreductase activity Catalysis of the reaction: formate + NADP(+) = CO(2) + NADPH. GO:0047898 formate dehydrogenase (cytochrome) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047898 MetaCyc:FORMATE-DEHYDROGENASE-CYTOCHROME-RXN|RHEA:21520|EC:1.2.2.1 formate:ferricytochrome-b1 oxidoreductase activity|formate:cytochrome b1 oxidoreductase activity Catalysis of the reaction: formate + ferricytochrome b1 = CO2 + ferrocytochrome b1. GO:0047897 formate-dihydrofolate ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047897 MetaCyc:FORMATE--DIHYDROFOLATE-LIGASE-RXN|RHEA:24328|EC:6.3.4.17|KEGG_REACTION:R02238 formate:dihydrofolate ligase (ADP-forming)|formyl dihydrofolate synthase activity|dihydrofolate formyltransferase activity Catalysis of the reaction: 7,8-dihydrofolate + ATP + formate = 10-formyldihydrofolate + ADP + H(+) + phosphate. GO:0047896 formaldehyde transketolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047896 MetaCyc:FORMALDEHYDE-TRANSKETOLASE-RXN|RHEA:24264|EC:2.2.1.3 glycerone synthase activity|dihydroxyacetone synthase activity|DHAS activity|D-xylulose-5-phosphate:formaldehyde glycolaldehydetransferase activity Catalysis of the reaction: D-xylulose 5-phosphate + formaldehyde = glyceraldehyde 3-phosphate + glycerone. GO:0047895 formaldehyde dismutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047895 MetaCyc:FORMALDEHYDE-DISMUTASE-RXN|EC:1.2.98.1|RHEA:19221 aldehyde dismutase activity|formaldehyde:formaldehyde oxidoreductase activity|cannizzanase activity|nicotinoprotein aldehyde dismutase Catalysis of the reaction: 2 formaldehyde + H2O = methanol + formate. GO:0047894 flavonol 3-sulfotransferase activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0047894 MetaCyc:FLAVONOL-3-SULFOTRANSFERASE-RXN|EC:2.8.2.25|KEGG_REACTION:R02159|RHEA:13453 flavonol 3-sulphotransferase activity|3'-phosphoadenylyl-sulfate:quercetin 3-sulfotransferase activity Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + quercetin = adenosine 3',5'-diphosphate + H(+) + quercetin 3-sulfate. GO:0047893 flavonol 3-O-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047893 RHEA:22300|EC:2.4.1.91|MetaCyc:FLAVONOL-3-O-GLUCOSYLTRANSFERASE-RXN uridine diphosphoglucose-flavonol 3-O-glucosyltransferase activity|UDP-glucose flavonol 3-O-glucosyltransferase activity|UDPglucose:flavonol 3-O-D-glucosyltransferase activity|UDP-glucose:flavonol 3-O-D-glucosyltransferase activity|GTI|UDPG:flavonoid-3-O-glucosyltransferase activity|UDP-glucose:flavonol 3-O-glucosyltransferase activity Catalysis of the reaction: UDP-glucose + a flavonol = UDP + a flavonol 3-O-D-glucoside. CHEBI:58530 gentamycin C1a(5+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58530 CHEBI:58538 (R)-3-hydroxy-2-oxo-4-(phosphonatoooxy)butanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58538 CHEBI:58537 cob(II)yrinic acid a,c diamide(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58537 CHEBI:58536 hydrogenobyrinic acid a,c-diamide(4-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58536 CHEBI:58535 N(8)-acetylspermidinium(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58535 CHEBI:58534 6-phospho-beta-D-galactoside(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58534 CHEBI:58533 S-methyl-5-thio-alpha-D-ribose 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58533 CHEBI:58532 precorrin-6Y(6-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58532 CHEBI:58531 Se-methyl-L-selenocysteine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58531 CHEBI:58529 P(1),P(3)-bis(5'-adenosyl) triphosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58529 CHEBI:58528 3-hydroxypropanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58528 UBERON:2001314 posterior lateral line ganglion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_2001314 The posterior lateral line ganglion develops from a cranial ectodermal placode and contains sensory neurons that innervate the posterior lateral line system. UBERON:2001316 anterior lateral line placode biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_2001316 pre-auditory lateral line placode|anterior lateral line placodes Dorsolateral placode that gives rise to the anterior lateral line. CHEBI:58527 D-ribosylnicotinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58527 CHEBI:58526 gibberellin A20(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58526 CHEBI:58525 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58525 CHEBI:58524 gibberellin A1(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58524 CHEBI:58523 (5S)-5-amino-3-oxohexanoic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58523 CHEBI:58522 precorrin-3B(7-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58522 CHEBI:58521 trans-3-enoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58521 CHEBI:58520 N-succinyl-L-glutamic 5-semialdehyde(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58520 CHEBI:58519 (E)-2-benzylidenesuccinyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58519 CHEBI:58518 precorrin-5(8-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58518 CHEBI:58517 3,4-dehydrothiomorpholine-3-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58517 CHEBI:58516 alpha-D-glucosamine 1-phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58516 CHEBI:58515 ectoine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58515 CHEBI:58514 N(2)-succinyl-L-ornithinate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58514 CHEBI:58513 precorrin-6X(8-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58513 CHEBI:58511 D-erythro-3-methylmalate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58511 CHEBI:58510 UDP-3-O-(3-hydroxytetradecanoyl)-D-glucosamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58510 CHEBI:58509 1-pyrroline-3-hydroxy-5-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58509 CHEBI:58507 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58507 CHEBI:58506 Ile(5)-angiotensin II dizwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58506 OBO:GOCHE_50113 substance with androgen role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_50113 OBO:GOCHE_50112 substance with sex hormone role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_50112 OBO:GOCHE_50114 substance with estrogen role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_50114 CHEBI:58505 mugineate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58505 CHEBI:58504 adenosylcobyrate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58504 CHEBI:58503 adenosylcob(III)yrinate a,c-diamide(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58503 CHEBI:58502 adenosylcobinamide phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58502 CHEBI:58501 7beta-aminocephalosporanic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58501 CHEBI:58500 7,8-diaminononanoate cation biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58500 UBERON:0015593 frontal gyrus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015593 A gyrus that is part of a frontal cortex. CHEBI:34528 adipoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_34528 CHEBI:10545 electron biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_10545 UBERON:2001391 anterior lateral line ganglion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_2001391 anterior lateral line ganglia The anteror lateral line ganglia develops from cranial ectodermal placodes and contain sensory neurons that innervate the anterior lateral line system. CHEBI:10577 gamma-terpinene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_10577 CHEBI:10576 (3R,4S,5S,6R)-1,3,4,5,6-pentachlorocyclohexene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_10576 UBERON:2001389 regeneration epithelium of fin/limb biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_2001389 wound epithelium of fin|epidermal cap|wound epidermis|wound epidermis of fin|epidermal cap of fin|wound epithelium A epithelium that is part of a regenerating fin/limb. UBERON:2001388 epithelial mesenchymal boundary of regenerating fin/limb biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_2001388 A epithelial-mesenchymal boundary that is part of a regenerating fin/limb. GO:0033409 UAU codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033409 TAT codon-amino acid adaptor activity|tyrosine tRNA A triplet codon-amino acid adaptor activity that recognizes a UAU codon. GO:0033408 UCG codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033408 TCG codon-amino acid adaptor activity|serine tRNA A triplet codon-amino acid adaptor activity that recognizes a UCG codon. GO:0033407 UCA codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033407 serine tRNA|TCA codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a UCA codon. GO:0033406 UCC codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033406 TCC codon-amino acid adaptor activity|serine tRNA A triplet codon-amino acid adaptor activity that recognizes a UCC codon. GO:0008449 N-acetylglucosamine-6-sulfatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008449 MetaCyc:3.1.6.14-RXN|Reactome:R-HSA-1638032|Reactome:R-HSA-2263495|EC:3.1.6.14 N-acetylglucosamine-6-sulphatase activity|acetylglucosamine 6-sulfatase activity|O,N-disulfate O-sulfohydrolase activity|glucosamine-6-sulfatase activity|N-acetylglucosamine 6-sulfate sulfatase activity|2-acetamido-2-deoxy-D-glucose 6-sulfate sulfatase activity|chondroitinsulfatase|N-acetyl-D-glucosamine-6-sulfate 6-sulfohydrolase activity Catalysis of the hydrolysis of the 6-sulfate group of the N-acetyl-D-glucosamine 6-sulfate units of heparan sulfate and keratan sulfate. GO:0033405 UCU codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033405 TCT codon-amino acid adaptor activity|serine tRNA A triplet codon-amino acid adaptor activity that recognizes a UCU codon. GO:0008448 N-acetylglucosamine-6-phosphate deacetylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008448 Reactome:R-HSA-6803789|RHEA:22936|EC:3.5.1.25|MetaCyc:NAG6PDEACET-RXN acetylglucosamine phosphate deacetylase activity|N-acetyl-D-glucosamine-6-phosphate amidohydrolase activity|acetylaminodeoxyglucosephosphate acetylhydrolase activity|2-acetamido-2-deoxy-D-glucose-6-phosphate amidohydrolase activity Catalysis of the reaction: N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate. GO:0033404 UUG codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033404 TTG codon-amino acid adaptor activity|leucine tRNA A triplet codon-amino acid adaptor activity that recognizes a UUG codon. GO:0008447 L-ascorbate oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008447 EC:1.10.3.3|MetaCyc:L-ASCORBATE-OXIDASE-RXN|RHEA:30243 ascorbate oxidase activity|ascorbate dehydrogenase activity|ascorbic oxidase activity|L-ascorbate:O2 oxidoreductase activity|L-ascorbate:oxygen oxidoreductase activity|AAO|L-ascorbic acid oxidase activity|ascorbic acid oxidase activity|ascorbase activity|AA oxidase activity Catalysis of the reaction: 2 L-ascorbate + O2 = 2 dehydroascorbate + 2 H2O. GO:0033403 UUA codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033403 TTA codon-amino acid adaptor activity|leucine tRNA A triplet codon-amino acid adaptor activity that recognizes a UUA codon. GO:0008446 GDP-mannose 4,6-dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008446 MetaCyc:GDPMANDEHYDRA-RXN|Reactome:R-HSA-6787632|KEGG_REACTION:R00888|EC:4.2.1.47|RHEA:23820 guanosine diphosphomannose 4,6-dehydratase activity|GDP-D-mannose dehydratase activity|GDPmannose 4,6-dehydratase activity|GDP-mannose 4,6-hydro-lyase activity|Gmd|GDP-D-mannose 4,6-dehydratase activity|guanosine diphosphomannose oxidoreductase activity|guanosine 5'-diphosphate-D-mannose oxidoreductase activity|GDP-mannose 4,6-hydro-lyase (GDP-4-dehydro-6-deoxy-D-mannose-forming) Catalysis of the reaction: GDP-alpha-D-mannose = GDP-4-dehydro-6-deoxy-alpha-D-mannose + H(2)O. GO:0008445 D-aspartate oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008445 EC:1.4.3.1|Reactome:R-HSA-6810076|MetaCyc:D-ASPARTATE-OXIDASE-RXN|RHEA:12512 D-aspartic oxidase activity|D-aspartate:oxygen oxidoreductase (deaminating)|aspartic oxidase activity Catalysis of the reaction: D-aspartate + H2O + O2 = oxaloacetate + NH3 + hydrogen peroxide. GO:0008444 CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008444 KEGG_REACTION:R01801|EC:2.7.8.5|MetaCyc:PHOSPHAGLYPSYN-RXN|Reactome:R-HSA-1482939|RHEA:12593 phosphatidylglycerolphosphate synthase activity|phosphatidylglycerophosphate synthetase activity|glycerol phosphate phosphatidyltransferase activity|phosphatidylglycerol phosphate synthase activity|CDPdiacylglycerol-sn-glycerol-3-phosphate 3-phosphatidyltransferase activity|glycerol 3-phosphate phosphatidyltransferase activity|CDP-diacylglycerol:sn-glycerol-3-phosphate 3-phosphatidyltransferase activity|CDPdiacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity|sn-glycerol-3-phosphate phosphatidyltransferase activity|3-phosphatidyl-1'-glycerol-3'-phosphate synthase activity|phosphatidylglycerophosphate synthase activity|CDPdiacylglycerol:glycerol-3-phosphate phosphatidyltransferase activity|cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):sn-glycerol-3-phosphate phosphatidyltransferase activity|phosphatidylglycerol phosphate synthetase activity|glycerophosphate phosphatidyltransferase activity|PGP synthase activity|CDPdiacylglycerol:sn-glycero-3-phosphate phosphatidyltransferase activity Catalysis of the reaction: sn-glycerol 3-phosphate + CDP-diacylglycerol = 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate + CMP + H(+). GO:0008443 phosphofructokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008443 Catalysis of the transfer of a phosphate group, usually from ATP, to a phosphofructose substrate molecule. GO:0008442 3-hydroxyisobutyrate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008442 RHEA:17681|Reactome:R-HSA-70885|MetaCyc:3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN|EC:1.1.1.31|Reactome:R-HSA-508473 Catalysis of the reaction: 3-hydroxy-2-methylpropanoate + NAD+ = 2-methyl-3-oxopropanoate + NADH + H+. GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008441 Reactome:R-HSA-176606|Reactome:R-HSA-8953499|MetaCyc:325-BISPHOSPHATE-NUCLEOTIDASE-RXN|EC:3.1.3.7|RHEA:10040 3'-phosphoadenylylsulfate 3'-phosphatase activity|3'(2'),5'-bisphosphonucleoside 3'(2')-phosphohydrolase activity|DPNPase activity|adenosine-3'(2'),5'-bisphosphate 3'(2')-phosphohydrolase activity|3'(2'),5' bisphosphate nucleotidase activity|phosphoadenylate 3'-nucleotidase activity Catalysis of the reaction: adenosine 3',5'-bisphosphate + H2O = adenosine 5'-phosphate + phosphate. GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008440 Reactome:R-HSA-1855233|Reactome:R-HSA-1855153|MetaCyc:2.7.1.127-RXN|KEGG_REACTION:R03433|EC:2.7.1.127|RHEA:11020 ATP:1D-myo-inositol-1,4,5-trisphosphate 3-phosphotransferase activity|IP3K activity|Ins(1,4,5)P3 3-kinase activity|inositol trisphosphate 3-kinase activity|1D-myo-inositol-trisphosphate 3-kinase activity|inositol-trisphosphate 3-kinase activity|IP3 3-kinase activity|ins(1,4,5)P(3) 3-kinase activity Catalysis of the reaction: 1D-myo-inositol 1,4,5-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + 2 H(+). CHEBI:58497 N-acyl-L-aspartate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58497 OBO:GOCHE_64909 substance with poison role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_64909 CHEBI:58496 N-acetyl-D-amino acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58496 CHEBI:138107 (3S)-3-hydroxy-L-asparagine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138107 CHEBI:58495 (2S)-2-carbamoylpyrrolidin-1-ium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58495 CHEBI:138105 (S)-6-acetamido-3-aminohexanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138105 CHEBI:138109 alpha-D-mannosyl-(1->3)-alpha-D-mannosyl-(1->3)-alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-1-diphospho-ditrans,polycis-undecaprenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138109 CHEBI:58490 (+)-8'-hydroxyabscisate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58490 GO:0033402 UUC codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033402 TTC codon-amino acid adaptor activity|phenylalanine tRNA A triplet codon-amino acid adaptor activity that recognizes a UUC codon. PO:0020003 plant ovule biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0020003 óvulo vegetal (Spanish, exact)|胚珠 (Japanese, exact)|Poaceae ovule (narrow)|Zea ovule (narrow) A plant organ (PO:0009008) that has as parts a nucellus (PO:0020020) in which a female gametophyte (PO:0025279) is located, one or two integuments (PO:0020021), and a funicle (PO:0020006). CHEBI:138100 2-[(9S,11R)-epidioxy-(15S)-hydroperoxy-(5Z,13E)-prostadienoyl]-sn-glycero-3- phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138100 GO:0033401 UUU codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033401 phenylalanine tRNA|TTT codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a UUU codon. GO:0033400 trans-zeatin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033400 trans-zeatin metabolism The chemical reactions and pathways involving trans-zeatin, (2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol. CHEBI:138103 inorganic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138103 PO:0020001 plant ovary placenta biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0020001 Poaceae ovary placenta (narrow)|子房胎座 (Japanese, exact)|placenta de ovario (Spanish, exact)|Zea ovary placenta (narrow) A portion of placenta tissue (PO:0025078) which is part of a plant ovary (PO:0009072), and to which plant ovary ovules (PO:0025490) are attached. CHEBI:58499 L-pyrrolysine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58499 CHEBI:138102 4-(ADP-D-ribosyl)-L-aspartyl(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138102 CHEBI:138101 2-[(9S,11R)-epidioxy-(15S)-hydroxy-(5Z,13E)-prostadienoyl]-sn-glycero-3- phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138101 CHEBI:58498 6-acetamido-3-aminohexanoic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58498 GO:0008459 chondroitin 6-sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008459 Reactome:R-HSA-2018682|RHEA:11108|EC:2.8.2.17|Reactome:R-HSA-3595175|MetaCyc:CHONDROITIN-6-SULFOTRANSFERASE-RXN chondroitin 6-O-sulfotransferase activity|3'-phosphoadenylyl-sulfate:chondroitin 6'-sulfotransferase activity|3'-phosphoadenosine 5'-phosphosulfate (PAPS):chondroitin sulfate sulfotransferase activity|chondroitin 6-sulphotransferase activity|terminal 6-sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate. GO:0008458 carnitine O-octanoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008458 KEGG_REACTION:R03779|MetaCyc:CARNITINE-O-OCTANOYLTRANSFERASE-RXN|EC:2.3.1.137|RHEA:17177|Reactome:R-HSA-390281 medium-chain/long-chain carnitine acyltransferase activity|overt mitochondrial carnitine palmitoyltransferase|octanoyl-CoA:L-carnitine O-octanoyltransferase activity|easily solubilized mitochondrial carnitine palmitoyltransferase|carnitine medium-chain acyltransferase activity Catalysis of the reaction: (R)-carnitine + octanoyl-CoA = (S)-octanoylcarnitine + CoA. GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008457 RHEA:23004|EC:2.4.1.149|MetaCyc:2.4.1.163-RXN UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide beta-1,3-acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-acetyllactosaminide beta1->3-acetylglucosaminyltransferase|poly-N-acetyllactosamine extension enzyme activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide = UDP + N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide. GO:0008456 alpha-N-acetylgalactosaminidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008456 MetaCyc:3.2.1.49-RXN|RHEA:15085|EC:3.2.1.49 alpha-NAGA activity|N-acetyl-alpha-D-galactosaminidase activity|alpha-galactosidase B activity|N-acetyl-alpha-galactosaminidase activity|alpha-N-acetyl-D-galactosaminide N-acetylgalactosaminohydrolase activity|alpha-acetylgalactosaminidase activity Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in N-acetyl-alpha-D-galactosaminides. GO:0008455 alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008455 Reactome:R-HSA-975829|RHEA:12941|MetaCyc:2.4.1.143-RXN|EC:2.4.1.143|Reactome:R-HSA-4793955|Reactome:R-HSA-9694656 uridine diphosphoacetylglucosamine-mannoside alpha-1,6-acetylglucosaminyltransferase activity|UDP-GlcNAc:mannoside alpha-1,6 acetylglucosaminyltransferase activity|GnTII activity|uridine diphosphoacetylglucosamine-alpha-D-mannoside beta-1,2-acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-alpha-D-mannoside beta(1,2)-acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:6-(alpha-D-mannosyl)-beta-D-mannosyl-glycoprotein 2-beta-N-acetyl-D-glucosaminyltransferase activity|N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II activity|alpha-1,6-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase activity|alpha-1,6-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-mannoside alpha(1,6)-acetylglucosaminyltransferase activity|N-acetylglucosaminyltransferase II activity|uridine diphosphoacetylglucosamine-alpha-1,6-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity|acetylglucosaminyltransferase II activity|alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase activity|UDP-GlcNAc:mannoside alpha-(1,6) acetylglucosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R. GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008454 Reactome:R-HSA-9696980|Reactome:R-HSA-975903|MetaCyc:2.4.1.145-RXN|RHEA:16057|EC:2.4.1.145 alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase activity|GnTIV activity|uridine diphosphoacetylglucosamine-glycopeptide beta-4-acetylglucosaminyltransferase IV activity|N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IV activity|UDP-N-acetyl-D-glucosamine:3-[2-(N-acetyl-beta-D-glucosaminyl)-alpha-D-mannosyl]-glycoprotein 4-beta-N-acetyl-D-glucosaminyltransferase activity|beta-acetylglucosaminyltransferase IV activity|N-acetylglucosaminyltransferase IV activity|alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-glycopeptide beta4-acetylglucosaminyltransferase IV Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + (N-acetyl-beta-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,4-(N-acetyl-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R. GO:0008453 alanine-glyoxylate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008453 EC:2.6.1.44|RHEA:24248|Reactome:R-HSA-904864|Reactome:R-HSA-389684|MetaCyc:ALANINE--GLYOXYLATE-AMINOTRANSFERASE-RXN alanine--glyoxylate aminotransferase activity|alanine-glyoxylate aminotransferase activity|alanine-glyoxylic aminotransferase activity|AGT activity|L-alanine-glycine transaminase activity|L-alanine:glyoxylate aminotransferase activity Catalysis of the reaction: L-alanine + glyoxylate = pyruvate + glycine. GO:0008452 RNA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008452 Catalysis of the formation of a phosphodiester bond between a hydroxyl group at the end of one RNA chain and the 5'-phosphate group at the end of another. GO:0008451 obsolete X-Pro aminopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008451 aminopeptidase P|aminoacylproline aminopeptidase activity|proline aminopeptidase|Xaa-Pro aminopeptidase activity|X-Pro aminopeptidase activity OBSOLETE. Catalysis of the release of any N-terminal amino acid, including proline, that is linked with proline, even from a dipeptide or tripeptide. GO:0008450 obsolete O-sialoglycoprotein endopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008450 O-sialoglycoprotein endopeptidase activity|sialoglycoproteinase activity|sialoglycoprotease activity|glycophorin A proteinase activity|glycoproteinase activity|glycoprotease activity OBSOLETE. Catalysis of the hydrolysis of O-sialoglycoproteins; cleaves the -Arg31-Asp32- bond in glycophorin A. Does not cleave unglycosylated proteins, desialylated glycoproteins or glycoproteins that are only N-glycosylated. GO:0008460 dTDP-glucose 4,6-dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008460 EC:4.2.1.46|MetaCyc:DTDPGLUCDEHYDRAT-RXN|KEGG_REACTION:R06513|RHEA:17221 dTDPglucose 4,6-hydro-lyase activity|TDP-glucose oxidoreductase activity|dTDP-glucose 4,6-hydro-lyase activity|thymidine diphosphoglucose oxidoreductase activity|dTDP-glucose 4,6-hydro-lyase (dTDP-4-dehydro-6-deoxy-D-glucose-forming)|dTDPglucose 4,6-dehydratase activity Catalysis of the reaction: dTDP-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H(2)O. CHEBI:58485 3-hydroxy-16-methoxy-2,3-dihydrotabersoninium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58485 CHEBI:58484 1D-myo-inositol 1,2-cyclic phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58484 CHEBI:58483 2-C-methyl-D-erythritol 2,4-cyclic diphosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58483 CHEBI:58482 (RS)-norcoclaurinium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58482 PR:000009799 leukemia inhibitory factor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000009799 MLPLI|D factor|LIF|melanoma-derived LPL inhibitor|emfilermin|differentiation-stimulating factor|HILDA A protein that is a translation product of the human LIF gene or a 1:1 ortholog thereof. CHEBI:58481 (RS)-coclaurinium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58481 CHEBI:58480 N-[(R)-pantothenoyl]-L-cysteinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58480 CHEBI:138111 (3S)-3-hydroxy-L-aspartate residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138111 PR:000019110 beta-2-microglobulin proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000019110 B2M/ClvPrd A beta-2-microglobulin that has been processed by proteolytic cleavage. CHEBI:138110 16(S)-HETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138110 CHEBI:58489 5-guanidino-2-oxopentanoic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58489 CHEBI:138114 O-guanylyl-L-tyrosine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138114 CHEBI:58488 3-epi-3-hydroxymugineate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58488 CHEBI:138113 O-adenyl-L-threonine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138113 CHEBI:58487 2'-deoxymugineate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58487 CHEBI:138112 chondroitin 4',6'-disulfate anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138112 GO:0008429 phosphatidylethanolamine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008429 Interacting selectively and non-covalently with phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine. GO:0008428 ribonuclease inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008428 Stops, prevents or reduces the activity of a ribonuclease, any enzyme that catalyzes the hydrolysis of phosphodiester bonds in chains of RNA. GO:0008427 calcium-dependent protein kinase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008427 Stops, prevents or reduces the activity of a calcium-dependent protein kinase. GO:0008426 protein kinase C inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008426 PKC inhibitor activity|diacylglycerol-activated phospholipid-dependent protein kinase C inhibitor activity|diacylglycerol-activated phospholipid-dependent PKC inhibitor activity Stops, prevents or reduces the activity of protein kinase C, an enzyme which phosphorylates a protein. CHEBI:128769 isopentenyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_128769 GO:0008425 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008425 EC:2.1.1.- 2-polyprenyl-6-methoxy-1,4-benzoquinone methylase activity|coenzyme Q biosynthetic process methyltransferase activity|coenzyme Q biosynthesis methyltransferase activity|ubiquinone biosynthesis methyltransferase activity|ubiquinone biosynthetic process methyltransferase activity Catalysis of the reaction: 2-polyprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine. GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008424 Reactome:R-HSA-1028788|MetaCyc:2.4.1.68-RXN|EC:2.4.1.68|Reactome:R-HSA-9696980|KEGG_REACTION:R05988|RHEA:12985 GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha-(1,6)fucosyltransferase activity|GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha(1->6)fucosyltransferase activity|GDPfucose-glycoprotein fucosyltransferase activity|FucT|GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha(1,6)fucosyltransferase activity|GDP-L-fucose--glycoprotein fucosyltransferase activity|GDP-fucose--glycoprotein fucosyltransferase activity|GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha-(1->6)fucosyltransferase activity|guanosine diphosphofucose--glycoprotein fucosyltransferase activity|glycoprotein fucosyltransferase activity Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP-L-fucose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-[alpha-L-fucosyl-(1->6)]-N-acetyl-beta-D-glucosaminyl}asparagine + GDP + H(+). GO:0008423 obsolete bleomycin hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008423 aminopeptidase C (Lactococcus lactis)|bleomycin hydrolase activity OBSOLETE. Catalysis of the inactivation of bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a peptide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred. GO:0008422 beta-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008422 MetaCyc:3.2.1.21-RXN|EC:3.2.1.21 beta-glucoside glucohydrolase activity|primeverosidase activity|limarase activity|salicilinase activity|aryl-beta-glucosidase activity|beta-D-glucoside glucohydrolase activity|beta-1,6-glucosidase activity|amygdalase activity|cellobiase activity|emulsin|p-nitrophenyl beta-glucosidase activity|gentobiase activity|cytokine beta-glucosidase activity|gentiobiase activity|beta-D-glucosidase activity|amygdalinase|arbutinase activity|elaterase activity Catalysis of the hydrolysis of terminal, non-reducing beta-D-glucose residues with release of beta-D-glucose. GO:0008421 long-chain fatty-acyl-glutamate deacylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008421 MetaCyc:3.5.1.55-RXN|RHEA:17517|EC:3.5.1.55 long-chain acylglutamate amidase activity|long-chain aminoacylase activity|long-chain-fatty-acyl-glutamate deacylase activity|N-long-chain-fatty-acyl-L-glutamate amidohydrolase activity|long-chain fatty acyl-glutamate deacylase activity Catalysis of the reaction: N-long-chain-fatty-acyl-L-glutamate + H2O = a fatty acid anion + L-glutamate. GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008420 RNA polymerase II carboxy-terminal domain phosphatase activity|CTD phosphatase activity Catalysis of the reaction: phospho-(DNA-directed RNA polymerase II) + H2O = (DNA-directed RNA polymerase II) + phosphate. CHEBI:58475 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58475 CHEBI:58474 3,6-dioxocyclohexa-1,4-dien-1-olate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58474 CHEBI:58473 codeinone(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58473 CHEBI:58472 beta-D-mannosyldiacetylchitobiosyldiphosphodolichol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58472 CHEBI:58471 bis(beta-glucosyluronate)bilirubin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58471 CHEBI:58470 apigenin-7-olate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58470 CHEBI:58479 N-formimidoylglycine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58479 CHEBI:58478 2-formamido-N(1)-(5-O-phosphonato-D-ribosyl)acetamidine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58478 CHEBI:58477 N(omega)-phosphonato-L-arginine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58477 CHEBI:58476 (2S)-2-hydroxy-2-methyl-3-oxobutanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58476 GO:0008439 obsolete monophenol monooxygenase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008439 prophenol oxidase activator|monophenol monooxygenase activator activity OBSOLETE. Increases the activity of the enzyme monophenol monooxygenase. GO:0008438 obsolete 1-phosphatidylinositol-5-phosphate kinase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008438 1-phosphatidylinositol-5-phosphate kinase OBSOLETE. Catalysis of the reaction: diphosphate + a purine nucleoside = phosphate + a purine mononucleotide. GO:0008437 thyrotropin-releasing hormone activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008437 TRH activity|thyrotropin releasing hormone activity The action characteristic of thyrotropin-releasing hormone (TRH), a hormone released by the mammalian hypothalamus into the hypophyseal-portal circulation in response to neural and/or chemical stimuli. Upon receptor binding, TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary. GO:0008436 obsolete heterogeneous nuclear ribonucleoprotein biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008436 heterogeneous nuclear ribonucleoprotein|hnRNP OBSOLETE. (Was not defined before being made obsolete). GO:0008435 obsolete anticoagulant activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008435 anticoagulant activity OBSOLETE. Functions to retard or prevent coagulation. Often used in the context of blood or milk coagulation. GO:0008434 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008434 GO:0008433 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008433 GO:0008432 JUN kinase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008432 JNK binding Interacting selectively and non-covalently with JUN kinase, an enzyme that catalyzes the phosphorylation and activation of members of the JUN family. GO:0008431 vitamin E binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008431 tocopherol binding|alpha-tocopherol binding Interacting selectively and non-covalently with vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant. CHEBI:128770 12,18-dihydroxyoctadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_128770 GO:0008430 selenium binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008430 Interacting selectively and non-covalently with selenium (Se). CHEBI:58464 nucleoside 3',5'-cyclic phosphate anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58464 CHEBI:58463 (7S)-salutaridinol(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58463 CHEBI:58462 7,8-dihydroneopterin 3'-triphosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58462 CHEBI:58461 17-O-deacetylvindolinium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58461 CHEBI:58460 13-(2-methylcrotonoyloxy)lupaninium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58460 CHEBI:58469 1D-myo-inositol 4-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58469 CHEBI:58468 3-aminoalanine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58468 CHEBI:58467 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58467 CHEBI:58466 2,3,2',3'-tetrakis(3-hydroxytetradecanoyl)-alpha-D-glucosaminyl-1,6-beta-D-glucosamine 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58466 CHEBI:58465 dermatan sulfate polyanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58465 GO:0008409 5'-3' exonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008409 Reactome:R-HSA-5358619|Reactome:R-HSA-5358599 Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 5' end. GO:0008408 3'-5' exonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008408 Reactome:R-HSA-3245943 3'-5'-exonuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end. GO:0008407 chaeta morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008407 bristle morphogenesis The process in which the anatomical structures of the chaeta are generated and organized. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell. GO:0008406 gonad development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008406 gonadogenesis The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones. GO:0008405 arachidonic acid 11,12-epoxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008405 RHEA:51480 cytochrome P450 CYP2C38 Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to cis-11,12-epoxyeicosatrienoic acid. GO:0008404 arachidonic acid 14,15-epoxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008404 RHEA:51472 cytochrome P450 CYP2C29|cytochrome P450 CYP2C39 Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to cis-14,15-epoxyeicosatrienoic acid. GO:0008403 25-hydroxycholecalciferol-24-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008403 25-hydroxyvitamin D3 24-hydroxylase activity|cytochrome P450 CYP24 Catalysis of the hydroxylation of C-24 of 25-hydroxycholecalciferol (25-hydroxyvitamin D3) to form 24(R),25-dihydroxycholecalciferol. GO:0008402 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008402 GO:0008401 retinoic acid 4-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008401 Reactome:R-HSA-211923|Reactome:R-HSA-5602063|Reactome:R-HSA-212007|Reactome:R-HSA-211874|Reactome:R-HSA-5362525|Reactome:R-HSA-5602050 cytochrome P450 CYP261 Catalysis of the conversion of retinoic acid to 4-hydroxy-retinoic acid. GO:0008400 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008400 CHEBI:58453 5-amino-6-(5-phospho-D-ribosylamino)uracil(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58453 CHEBI:58452 4-(phosphonatooxy)-L-threonine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58452 CHEBI:34485 8(R)-HPODE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_34485 CHEBI:58451 pyridoxamine 5'-phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58451 CHEBI:58450 adenosine 5'-tetraphosphate(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58450 CHEBI:34487 8(S)-HPETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_34487 PO:0020047 microsporocyte biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0020047 microsporocito (Spanish, exact)|小胞子母細胞 (Japanese, exact)|Zea microsporocyte (narrow)|pollen mother cell (related)|PMC (related)|Poaceae microsporocyte (narrow)|microspore mother cell (related) A sporocyte (PO:0006204) that produces four haploid (1n) microspores (PO:0020048). PO:0020049 leaflet biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0020049 pinnule (narrow)|小葉 (Japanese, exact)|pinnae (narrow)|folíolo (Spanish, exact)|pinna (narrow) A cardinal organ part (PO:0025001) that is one of the ultimate segments of a compound leaf (PO:0020043). CHEBI:58459 pyrroloquinoline quinol(3-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58459 PO:0020048 microspore biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0020048 小胞子 (Japanese, exact)|Poaceae microspore (narrow)|microspora (Spanish, exact)|Zea microspore (narrow) The smaller, in general, of the two kinds of spores produced after meiosis in the life cycle of a heterosporous plant, and on germination giving rise to the male gametophyte. CHEBI:58458 (R)-2-hydroxypropyl-CoM(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58458 PO:0020043 compound leaf biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0020043 複葉 (Japanese, exact)|hoja compuesta (Spanish, exact) A leaf having two or more distinct leaflets that are evident as such from early in development. CHEBI:58457 N(1)-(5-phospho-D-ribosyl)glycinamide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58457 PO:0020042 simple leaf biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0020042 hoja simple (Spanish, exact)|単葉 (Japanese, exact) A leaf in which the lamina is undivided. CHEBI:58456 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58456 CHEBI:58455 L-2-aminohexanoic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58455 CHEBI:58454 kynurenate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58454 CHEBI:34483 7-hydroxyflavanone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_34483 PO:0020041 stipule biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0020041 托葉 (Japanese, exact)|estípula (Spanish, exact) A cardinal organ part that is an appendage at the base of a vascular leaf. GO:0008419 RNA lariat debranching enzyme activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008419 Catalysis of the hydrolysis of branched RNA structures that contain vicinal 2'-5'- and 3'-5'-phosphodiester bonds at a branch point nucleotide. GO:0008418 protein-N-terminal asparagine amidohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008418 Catalysis of the reaction: protein-L-asparagine + H2O = protein-L-aspartate + NH3. This reaction is the deamidation of an N-terminal asparagine residue in a peptide or protein. GO:0008417 fucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008417 Reactome:R-HSA-9033949 Catalysis of the transfer of a fucosyl group to an acceptor molecule, typically another carbohydrate or a lipid. GO:0008416 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008416 PR:000020135 hepatocyte growth factor proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000020135 HGF/ClvPrd A hepatocyte growth factor that has been processed by proteolytic cleavage. GO:0008415 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008415 GO:0008414 CDP-alcohol phosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008414 Catalysis of the transfer of a CDP-alcohol group from one compound to another. GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008413 EC:3.6.1.69|RHEA:60032 8-oxo-7,8-dihydroguanine triphosphatase activity|8-oxo-7,8-dihydroguanosine triphosphatase activity|8-oxo-GTPase activity|7,8-dihydro-8-oxoguanine-triphosphatase activity Catalysis of the reaction: 8-oxo-7,8-dihydroguanosine triphosphate (8-oxo-GTP) + H2O = 8-oxo-7,8-dihydroguanosine diphosphate (8-oxo-GDP) + phosphate. 8-oxo-7,8-dihydroguanosine triphosphate (8-oxo-GTP) is the oxidised form of the free guanine nucleotide and can act as a potent mutagenic substrate for transcription. GO:0008412 4-hydroxybenzoate octaprenyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008412 MetaCyc:4OHBENZOATE-OCTAPRENYLTRANSFER-RXN|RHEA:27782|EC:2.5.1.- para-hydroxybenzoate:polyprenyltransferase activity|para-hydroxybenzoate transferase activity|PHB polyprenyl diphosphate transferase activity|para-hydroxybenzoate-polyprenyl diphosphate transferase activity|4-HB polyprenyltransferase activity Catalysis of the reaction: farnesylfarnesylgeranyl diphosphate + p-hydroxybenzoate = 3-octaprenyl-4-hydroxybenzoate + diphosphate. GO:0008411 4-hydroxybutyrate CoA-transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008411 Catalysis of the transfer of a coenzyme A (CoA) group to 4-hydroxybutyrate. CHEBI:128754 GDP-valienol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_128754 CHEBI:128753 (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_128753 GO:0008410 CoA-transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008410 Reactome:R-HSA-70713|EC:2.8.3.- Catalysis of the transfer of a coenzyme A (CoA) group from one compound (donor) to another (acceptor). CHEBI:58442 pyrroloquinoline quinone(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58442 CHEBI:34497 9(S)-HPETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_34497 CHEBI:58441 L-2-aminopentanoic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58441 CHEBI:34496 9(S)-HODE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_34496 CHEBI:58440 quinoline-4-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58440 CHEBI:34498 9(S)-HPODE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_34498 CHEBI:58448 L-thyroxine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58448 CHEBI:58447 isovitexin-7-olate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58447 CHEBI:34490 8,9-EET biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_34490 CHEBI:58446 13-hydroxylupaninium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58446 CHEBI:58445 anserine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58445 PO:0020031 radicle biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0020031 radícula (Spanish, exact)|幼根 (Japanese, exact) An embryo root (PO:0000045) that is the basal continuation of a hypocotyl (PO:0020100) in a plant embryo (PO:0009009) or a seedling (PO:0000003). CHEBI:58444 1-(sn-glycero-3-O-phosphonato)-1D-myo-inositol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58444 CHEBI:34494 9(10)-EpOME biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_34494 CHEBI:58443 SAICAR(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58443 PO:0020030 cotyledon biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0020030 cotiledón (Spanish, exact)|seed leaf (exact)|子葉 (Japanese, exact) A vascular leaf (PO:0009025) formed at the first shoot node (PO:0005004) of a plant embryo (PO:0009009) or a seedling (PO:0000003). PR:000020124 orexin proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000020124 HCRT/ClvPrd An orexin that has been processed by proteolytic cleavage. CHEBI:58431 jasmonate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58431 CHEBI:58430 (S)-2-hydroxypropyl-CoM(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58430 CHEBI:58439 UDP-D-galactose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58439 CHEBI:58438 thiaminium carboxylate betaine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58438 CHEBI:58437 deamido-NAD(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58437 CHEBI:58436 phosphatidyl-L-serine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58436 PO:0020021 integument biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0020021 Zea integument (narrow)|integumento (Spanish, exact)|Poaceae integument (narrow)|珠皮 (Japanese, exact)|portion of integument tissue (exact) A portion of plant tissue (PO:0009007) that usually covers a plant ovule (PO:0020003), enveloping a nucellus (PO:0020020) and forming a micropyle (PO:0020025) at the apex. CHEBI:58435 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58435 CHEBI:58434 (2Z,4E)-4-hydroxymuconic semialdehyde(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58434 CHEBI:58433 1D-myo-inositol 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58433 CHEBI:58432 histaminium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58432 CHEBI:58429 alpha,alpha-trehalose 6-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58429 CHEBI:58420 cis-5,6-dihydroxy-4-isopropylcyclohexa-1,3-dienecarboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58420 CHEBI:34477 6beta-hydroxytestosterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_34477 PO:0020019 megaspore biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0020019 大胞子 (Japanese, exact)|Poaceae megaspore (narrow)|Zea megaspore (narrow)|megaspora (Spanish, exact)|macrospore (related) The larger, in general, of the two kinds of spores produced after meiosis in the life cycle of a heterosporous plant, and on germination giving rise to the female gametophyte (embryo sac). CHEBI:58427 N-acetyl-D-glucosaminyldiphosphodolichol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58427 PR:000019130 brain-derived neurotrophic factor proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000019130 BDNF/ClvPrd A brain-derived neurotrophic factor that has been processed by proteolytic cleavage. CHEBI:58426 N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58426 CHEBI:58425 5-oxo-4,5-dihydro-2-furylacetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58425 CHEBI:58424 1-(5-phospho-D-ribosyl)-ATP(6-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58424 CHEBI:58423 UDP-D-galactofuranose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58423 CHEBI:58422 chondroitin 4'-sulfate anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58422 CHEBI:58421 5-amino-6-(5-phosphoribitylamino)uracil(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58421 CHEBI:138191 3'-end 3'-(N-acyl-L-alpha-aminoacyl)adenylyl(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138191 CHEBI:138195 1,2-diheptanoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138195 CHEBI:138194 1,2-dihexanoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138194 CHEBI:138193 (2R,5S)-2,5-diaminohexanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138193 GO:0033482 D-galacturonate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033482 D-galacturonate synthesis|D-galacturonate biosynthesis|D-galacturonate formation|D-galacturonate anabolism The chemical reactions and pathways resulting in the formation of D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid. GO:0033481 galacturonate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033481 galacturonate biosynthesis|galacturonate anabolism|galacturonate synthesis|galacturonate formation The chemical reactions and pathways resulting in the formation of galacturonate, the anion of galacturonic acid. GO:0033480 UDP-D-galacturonate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033480 MetaCyc:PWY-4 UDP-D-galacturonate anabolism|UDP-D-galacturonate synthesis|UDP-D-galacturonate formation|UDP-D-galacturonate biosynthesis The chemical reactions and pathways resulting in the formation of UDP-D-galacturonate, a substance composed of galacturonic acid in glycosidic linkage with uridine diphosphate. CHEBI:138188 (2R,3R)-dihydroflavonol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138188 GO:0033489 cholesterol biosynthetic process via desmosterol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033489 MetaCyc:PWY66-4 cholesterol anabolism via desmosterol|cholesterol synthesis via desmosterol|cholesterol formation via desmosterol|cholesterol biosynthesis via desmosterol The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate desmosterol. GO:0033488 cholesterol biosynthetic process via 24,25-dihydrolanosterol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033488 MetaCyc:PWY66-3 cholesterol anabolism via 24,25-dihydrolanosterol|cholesterol synthesis via 24,25-dihydrolanosterol|cholesterol formation via 24,25-dihydrolanosterol|cholesterol biosynthesis via 24,25-dihydrolanosterol The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate 24,25-dihydrolanosterol. GO:0033487 pelargonidin 3-O-glucoside biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033487 MetaCyc:PWY-5125 pelargonidin 3-O-glucoside biosynthesis|pelargonidin 3-O-glucoside anabolism|pelargonidin 3-O-glucoside synthesis|pelargonidin 3-O-glucoside formation The chemical reactions and pathways resulting in the formation of pelargonidin 3-O-glucoside, a basic anthocyanin responsible for red to magenta coloration of flowers and fruits. GO:0033486 delphinidin 3-O-glucoside biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033486 MetaCyc:PWY-5153 delphinidin 3-O-glucoside anabolism|delphinidin 3-O-glucoside synthesis|delphinidin 3-O-glucoside formation|delphinidin 3-O-glucoside biosynthesis The chemical reactions and pathways resulting in the formation of delphinidin 3-O-glucoside, a basic, water-soluble anthocyanin responsible for blue coloration of flowers and fruits. GO:0033485 cyanidin 3-O-glucoside biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033485 MetaCyc:PWY-5125 cyanidin 3-O-glucoside anabolism|cyanidin 3-O-glucoside synthesis|cyanidin 3-O-glucoside formation|cyanidin 3-O-glucoside biosynthesis The chemical reactions and pathways resulting in the formation of cyanidin 3-O-glucoside, a basic anthocyanin responsible for red to magenta coloration of flowers and fruits. GO:0033484 nitric oxide homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033484 NO homeostasis A homeostatic process involved in the maintenance of an internal steady state of nitric oxide within an organism or cell. GO:0033483 gas homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033483 A homeostatic process involved in the maintenance of an internal steady state of a gas within an organism or cell. GO:0033471 GDP-L-galactose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033471 GDP-L-galactose metabolism The chemical reactions and pathways involving GDP-L-galactose, a substance composed of L-galactose in glycosidic linkage with guanosine diphosphate. GO:0033470 gibberellin 12 biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033470 MetaCyc:PWY-5034 GA12 biosynthetic process|gibberellin A12 biosynthetic process|gibberellin 12 biosynthesis|gibberellin 12 anabolism|gibberellin 12 synthesis|gibberellin 12 formation The chemical reactions and pathways resulting in the formation of gibberellin 12, (1R,2S,3S,4R,8S,9S,12R)-4,8-dimethyl-13-methylidenetetracyclo[10.2.1.01,9.03,8]pentadecane-2,4-dicarboxylic acid 1meta,4a-dimethyl-8-methylidene-4aalpha,4bbeta-gibbane-1alpha,10beta-dicarboxylic acid. GO:0033479 UDP-D-galacturonate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033479 UDP-D-galacturonate metabolism The chemical reactions and pathways involving UDP-D-galacturonate, a substance composed of galacturonic acid in glycosidic linkage with uridine diphosphate. CHEBI:138199 1-hexadecanoyl-2-heptanoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138199 GO:0033478 UDP-rhamnose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033478 MetaCyc:PWY-3261 UDP-rhamnose metabolism The chemical reactions and pathways involving UDP-L-rhamnose, a substance composed of rhamnose in glycosidic linkage with uridine diphosphate. CHEBI:138198 1-heptanoyl-2-hexanoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138198 GO:0033477 S-methylmethionine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033477 S-methylmethionine metabolism The chemical reactions and pathways involving S-methyl-methionine (SMM). SMM can be converted to methionine by donating a methyl group to homocysteine, and concurrent operation of this reaction and that mediated by MMT sets up the SMM cycle. CHEBI:138197 1-hexanoyl-2-heptanoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138197 CHEBI:138196 19-hydroxyleukotriene B4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138196 GO:0033476 indoleacetic acid ester conjugate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033476 MetaCyc:PWY-1741 indoleacetic acid ester conjugate anabolism|indoleacetic acid ester conjugate synthesis|indole acetic acid ester conjugate biosynthetic process|indole acetic acid ester conjugate biosynthesis|indoleacetic acid ester conjugate formation|indoleacetic acid ester conjugate biosynthesis|IAA ester conjugate biosynthetic process The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid amide conjugate, a form of indoleacetic acid covalently bound to an a sugar or polyol through an ester bond. GO:0033475 indoleacetic acid amide conjugate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033475 MetaCyc:PWY-1782 indoleacetic acid amide conjugate synthesis|indoleacetic acid amide conjugate formation|indoleacetic acid amide conjugate biosynthesis|IAA amide conjugate biosynthetic process|indole acetic acid amide conjugate biosynthetic process|indole acetic acid amide conjugate biosynthesis|indoleacetic acid amide conjugate anabolism The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid amide conjugate, a form of indoleacetic acid covalently bound to an amino acid or polypeptide through an amide bond. GO:0033474 indoleacetic acid conjugate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033474 indoleacetic acid conjugate formation|IAA conjugate biosynthetic process|indoleacetic acid conjugate biosynthesis|indole acetic acid conjugate biosynthetic process|indole acetic acid conjugate biosynthesis|indoleacetic acid conjugate anabolism|indoleacetic acid conjugate synthesis The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid conjugate, a form of indoleacetic acid covalently bound to another molecule. GO:0033473 indoleacetic acid conjugate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033473 indoleacetic acid conjugate metabolism|IAA conjugate metabolic process|indole acetic acid conjugate metabolic process|indole acetic acid conjugate metabolism The chemical reactions and pathways involving any indole-3-acetic acid conjugate, a form of indoleacetic acid covalently bound to another molecule. GO:0033472 GDP-L-galactose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033472 MetaCyc:PWY-5115 GDP-L-galactose biosynthesis|GDP-L-galactose anabolism|GDP-L-galactose synthesis|GDP-L-galactose formation The chemical reactions and pathways resulting in the formation of GDP-L-galactose, a substance composed of L-galactose in glycosidic linkage with guanosine diphosphate. CHEBI:138171 pApA(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138171 GO:0033469 gibberellin 12 metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033469 gibberellin 12 metabolism|gibberellin A12 metabolic process|GA12 metabolic process The chemical reactions and pathways involving gibberellin 12, (1R,2S,3S,4R,8S,9S,12R)-4,8-dimethyl-13-methylidenetetracyclo[10.2.1.01,9.03,8]pentadecane-2,4-dicarboxylic acid 1meta,4a-dimethyl-8-methylidene-4aalpha,4bbeta-gibbane-1alpha,10beta-dicarboxylic acid. GO:0033460 GAG codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033460 glutamic acid tRNA A triplet codon-amino acid adaptor activity that recognizes a GAG codon. GO:0033468 CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033468 MetaCyc:PWY-1269|MetaCyc:PWY-5111|MetaCyc:KDOSYN-PWY CMP-keto-3-deoxy-D-manno-octulosonic acid anabolism|CMP-keto-3-deoxy-D-manno-octulosonic acid synthesis|CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthesis|CMP-keto-3-deoxy-D-manno-octulosonic acid formation|CMP-KDO biosynthetic process|CMP-KDO biosynthesis|CMP-ketodeoxyoctanoate biosynthetic process The chemical reactions and pathways resulting in the formation of CMP-keto-3-deoxy-D-manno-octulosonic acid, a substance composed of the acidic sugar 3-deoxy-D-manno-octulosonic acid in glycosidic linkage with cytidine monophosphate. CHEBI:138166 nezukol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138166 GO:0033467 CMP-keto-3-deoxy-D-manno-octulosonic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033467 CMP-keto-3-deoxy-D-manno-octulosonic acid metabolism|CMP-KDO metabolic process|CMP-ketodeoxyoctanoate metabolic process The chemical reactions and pathways involving CMP-keto-3-deoxy-D-manno-octulosonic acid, a substance composed of the acidic sugar 3-deoxy-D-manno-octulosonic acid in glycosidic linkage with cytidine monophosphate. CHEBI:138165 (+)-(2S,3R,9R)-pristinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138165 GO:0033466 trans-zeatin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033466 MetaCyc:PWY-2681 trans-zeatin biosynthesis|trans-zeatin anabolism|trans-zeatin synthesis|trans-zeatin formation The chemical reactions and pathways resulting in the formation of trans-zeatin, (2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol. GO:0033465 cis-zeatin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033465 MetaCyc:PWY-2781 cis-zeatin anabolism|cis-zeatin synthesis|cis-zeatin formation|cis-zeatin biosynthesis The chemical reactions and pathways resulting in the formation of cis-zeatin, (2Z)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol. GO:0033464 GGG codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033464 glycine tRNA A triplet codon-amino acid adaptor activity that recognizes a GGG codon. GO:0033463 GGA codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033463 glycine tRNA A triplet codon-amino acid adaptor activity that recognizes a GGA codon. GO:0033462 GGC codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033462 glycine tRNA A triplet codon-amino acid adaptor activity that recognizes a GGC codon. GO:0033461 GGU codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033461 glycine tRNA|GGT codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a GGU codon. CHEBI:138167 5-hydroxy-alpha-gurjunene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138167 GO:0033459 GAA codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033459 glutamic acid tRNA A triplet codon-amino acid adaptor activity that recognizes a GAA codon. CHEBI:83408 sn-glycerophosphodiester(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83408 GO:0033458 GAC codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033458 aspartic acid tRNA A triplet codon-amino acid adaptor activity that recognizes a GAC codon. CHEBI:83407 4-(phosphooxymethyl)-2-furancarboxaldehyde(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83407 CHEBI:83403 monochlorobenzenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83403 CHEBI:83402 nucleoside 3',5'-bisphosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83402 CHEBI:83401 anionic tRNA polymer biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83401 CHEBI:83400 RNA polyanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83400 CHEBI:138177 4-unsubstituted 3-hydroxyanthocyanidin betaine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138177 GO:0033457 GAU codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033457 aspartic acid tRNA|GAT codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a GAU codon. GO:0033456 GCG codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033456 alanine tRNA A triplet codon-amino acid adaptor activity that recognizes a GCG codon. CHEBI:138176 (2R,3S,4S)-leucoanthocyanidin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138176 GO:0033455 GCA codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033455 alanine tRNA A triplet codon-amino acid adaptor activity that recognizes a GCA codon. CHEBI:138175 O-[S-(L-alpha-aminoacyl)pantetheine-4'-phosphoryl]serine zwitterionic residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138175 GO:0033454 GCC codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033454 alanine tRNA A triplet codon-amino acid adaptor activity that recognizes a GCC codon. GO:0033453 GCU codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033453 alanine tRNA|GCT codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a GCU codon. GO:0033452 GUG codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033452 valine tRNA|GTG codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a GUG codon. GO:0033451 GUA codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033451 valine tRNA|GTA codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a GUA codon. GO:0033450 GUC codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033450 valine tRNA|GTC codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a GUC codon. CHEBI:138178 (4S)-2,3-dehydroflavan-3,4-diol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138178 GO:0033449 GUU codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033449 GTT codon-amino acid adaptor activity|valine tRNA A triplet codon-amino acid adaptor activity that recognizes a GUU codon. CHEBI:138150 D-tagatopyranose 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138150 CHEBI:83419 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate)(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83419 GO:0033448 AGG codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033448 arginine tRNA A triplet codon-amino acid adaptor activity that recognizes an AGG codon. GO:0033447 AGA codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033447 arginine tRNA A triplet codon-amino acid adaptor activity that recognizes an AGA codon. CHEBI:83418 S-(5-histidyl)cysteine sulfoxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83418 CHEBI:83417 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate)(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83417 CHEBI:83416 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate)(7-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83416 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008489 MetaCyc:RXN-10764 LacCer synthase activity|UDP-galactose glucosylceramide beta-1,4-galactosyltransferase activity|lactosylceramide synthase activity Catalysis of the reaction: UDP-D-galactose + a glucosylceramide = a lactosylceramide + uridine-5'-diphosphate. The glucosylceramide has sphinganine as the long chain base. GO:0008488 gamma-glutamyl carboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008488 Reactome:R-HSA-163820|Reactome:R-HSA-159826|Reactome:R-HSA-163810|Reactome:R-HSA-159752|Reactome:R-HSA-9673231|Reactome:R-HSA-159795|Reactome:R-HSA-6807214|EC:4.1.1.90|RHEA:45140|Reactome:R-HSA-159803|Reactome:R-HSA-159819|Reactome:R-HSA-159761 Catalysis of the reaction: peptidyl-glutamate + reduced vitamin K + CO2 + O2 = peptidyl-gamma-carboxyglutamate + vitamin K epoxide. GO:0008487 obsolete prenyl-dependent CAAX protease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008487 prenyl-dependent CAAX protease activity OBSOLETE. (Was not defined before being made obsolete). CHEBI:83414 alkyl sulfate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83414 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008486 MetaCyc:3.6.1.52-RXN|KEGG_REACTION:R05777|EC:3.6.1.52 DIPP activity|diphosphoinositol polyphosphate phosphohydrolase activity|diphospho-myo-inositol-polyphosphate diphosphohydrolase activity|diphosphoinositol-polyphosphate phosphohydrolase activity Catalysis of the reaction: diphospho-myo-inositol polyphosphate + H2O = myo-inositol polyphosphate + phosphate. GO:0008485 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008485 CHEBI:83412 N(5)-acyl-L-ornithine ester(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83412 GO:0008484 sulfuric ester hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008484 EC:3.1.6.-|MetaCyc:ARYLSULFAT-RXN sulphuric ester hydrolase activity|sulfatase activity Catalysis of the reaction: RSO-R' + H2O = RSOOH + R'H. This reaction is the hydrolysis of any sulfuric ester bond, any ester formed from sulfuric acid, O=SO(OH)2. CHEBI:83411 beta-D-glucosiduronate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83411 GO:0008483 transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008483 Reactome:R-HSA-1237102|RHEA:31763|EC:2.6.1.- aminotransferase activity Catalysis of the transfer of an amino group to an acceptor, usually a 2-oxo acid. CHEBI:83410 alpha-amino acid ester(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83410 GO:0008493 tetracycline transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008493 tetracycline transporter activity|tetracyclin transporter activity Enables the transfer of tetracycline from one side of a membrane to the other. Tetracycline is a broad spectrum antibiotic that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles). GO:0008492 obsolete cAMP generating peptide activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008492 cyclic AMP generating peptide activity|cAMP generating peptide activity OBSOLETE. (Was not defined before being made obsolete). GO:0008491 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008491 GO:0008490 arsenite secondary active transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008490 arsenite porter activity Enables the transfer of arsenite from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. PR:000009744 low-density lipoprotein receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000009744 LDL receptor|LDLR A protein that is a translation product of the human LDLR gene or a 1:1 ortholog thereof. GO:0033446 AGC codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033446 serine tRNA A triplet codon-amino acid adaptor activity that recognizes an AGC codon. GO:0033445 AGU codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033445 AGT codon-amino acid adaptor activity|serine tRNA A triplet codon-amino acid adaptor activity that recognizes an AGU codon. GO:0033444 AAG codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033444 lysine tRNA A triplet codon-amino acid adaptor activity that recognizes an AAG codon. GO:0033443 AAA codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033443 lysine tRNA A triplet codon-amino acid adaptor activity that recognizes an AAA codon. CHEBI:138141 17alpha-hydroxy-C21-steroid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138141 GO:0033442 AAC codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033442 asparagine tRNA A triplet codon-amino acid adaptor activity that recognizes an AAC codon. CHEBI:138148 3'-end deoxyribonucleotide(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138148 GO:0033441 AAU codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033441 AAT codon-amino acid adaptor activity|asparagine tRNA A triplet codon-amino acid adaptor activity that recognizes an AAU codon. CHEBI:138147 3'-end deoxyribonucleotide 3'-phosphate(3-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138147 CHEBI:138146 13-hydroxy-14,15-epoxy-(5Z,8Z,11Z)-icosatrienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138146 GO:0033440 ACG codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033440 threonine tRNA A triplet codon-amino acid adaptor activity that recognizes an ACG codon. CHEBI:138145 1,2-di-[(9Z)-hexadecenoyl]-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138145 GO:0033439 ACA codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033439 threonine tRNA A triplet codon-amino acid adaptor activity that recognizes an ACA codon. GO:0033438 ACC codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033438 threonine tRNA A triplet codon-amino acid adaptor activity that recognizes an ACC codon. GO:0033437 ACU codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033437 threonine tRNA|ACT codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes an ACU codon. GO:0033436 AUG codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033436 methionine tRNA|ATG codon-amino acid adaptor activity|initiator methionine tRNA A triplet codon-amino acid adaptor activity that recognizes an AUG codon. GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008499 Reactome:R-HSA-9603989|Reactome:R-HSA-914010 UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase activity|beta3Gal-Ts activity|beta-1,3-GalTase activity|UDP-galactose beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity Catalysis of the reaction: UDP-galactose + N-acetylglucosamine = galactose-beta-1,3-N-acetylglucosamine + UDP. GO:0008498 obsolete phospholipid scrambling biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008498 phospholipid scrambling OBSOLETE. The trans-bilayer migration of phospholipids accelerated by a phospholipid scramblase upon binding calcium ions. CHEBI:83425 gamma-glutamyltyramine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83425 GO:0008497 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008497 GO:0008496 mannan endo-1,6-alpha-mannosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008496 MetaCyc:3.2.1.101-RXN|EC:3.2.1.101|Reactome:R-HSA-6799581 mannan endo-1,6-beta-mannosidase activity|1,6-beta-D-mannan mannanohydrolase activity|endo-alpha-1->6-D-mannanase activity|exo-1,6-beta-mannanase activity|endo-alpha-D-mannosidase activity|1,6-alpha-D-mannan mannanohydrolase activity|endo-1,6-beta-mannanase activity Catalysis of the random hydrolysis of (1->6)-alpha-D-mannosidic linkages in unbranched (1->6)-mannans. CHEBI:83423 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate)(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83423 GO:0008495 protoheme IX farnesyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008495 EC:2.5.1.-|RHEA:28070|MetaCyc:HEMEOSYN-RXN|Reactome:R-HSA-2995330 haem O synthase activity|heme O synthase activity|protohaem IX farnesyltransferase activity|heme A:farnesyltransferase activity Catalysis of the reaction: protoheme IX + (2E,6E)-farnesyl diphosphate + H2O = heme o + diphosphate. CHEBI:83422 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate)(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83422 CHEBI:83421 O-phospho-L-serine(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83421 GO:0008494 translation activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008494 Any of a group of soluble proteins functioning in the activation of ribosome-mediated translation of mRNA into a polypeptide. CHEBI:83420 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate)(7-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83420 GO:0033435 AUA codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033435 ATA codon-amino acid adaptor activity|isoleucine tRNA A triplet codon-amino acid adaptor activity that recognizes an AUA codon. GO:0033434 AUC codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033434 ATC codon-amino acid adaptor activity|isoleucine tRNA A triplet codon-amino acid adaptor activity that recognizes an AUC codon. GO:0033433 AUU codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033433 ATT codon-amino acid adaptor activity|isoleucine tRNA A triplet codon-amino acid adaptor activity that recognizes an AUU codon. GO:0033432 CGG codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033432 arginine tRNA A triplet codon-amino acid adaptor activity that recognizes a CGG codon. GO:0033431 CGA codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033431 arginine tRNA A triplet codon-amino acid adaptor activity that recognizes a CGA codon. GO:0033430 CGC codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033430 arginine tRNA A triplet codon-amino acid adaptor activity that recognizes a CGC codon. GO:0033429 CGU codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033429 CGT codon-amino acid adaptor activity|arginine tRNA A triplet codon-amino acid adaptor activity that recognizes a CGU codon. GO:0033428 CAG codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033428 glutamine tRNA A triplet codon-amino acid adaptor activity that recognizes a CAG codon. GO:0033427 CAA codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033427 glutamine tRNA A triplet codon-amino acid adaptor activity that recognizes a CAA codon. GO:0033426 CAC codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033426 histidine tRNA A triplet codon-amino acid adaptor activity that recognizes a CAC codon. GO:0008469 histone-arginine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008469 Reactome:R-HSA-5205861|Reactome:R-HSA-5661117|Reactome:R-HSA-8936584|Reactome:R-HSA-5205799|Reactome:R-HSA-5216234|Reactome:R-HSA-8937022|Reactome:R-HSA-8937113|Reactome:R-HSA-8936608 protein methylase I activity|histone protein methylase I|S-adenosyl-L-methionine:histone-arginine omega-N-methyltransferase activity|histone methyltransferase activity|histone protein methylase activity|S-adenosyl-L-methionine:histone-arginine nomega-methyltransferase activity|nuclear protein (histone) N-methyltransferase activity|histone-arginine N-methylase activity Catalysis of the reaction: S-adenosyl-L-methionine + (histone)-arginine = S-adenosyl-L-homocysteine + (histone)-N-methyl-arginine. GO:0033425 CAU codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033425 CAT codon-amino acid adaptor activity|histidine tRNA A triplet codon-amino acid adaptor activity that recognizes a CAU codon. GO:0008468 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008468 CHEBI:83439 iminoarginine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83439 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008467 MetaCyc:2.8.2.23-RXN|EC:2.8.2.23|Reactome:R-HSA-2076383|Reactome:R-HSA-2076611 heparan sulfate D-glucosaminyl 3-O-sulfotransferase activity|3'-phosphoadenylyl-sulfate:heparin-glucosamine 3-O-sulfotransferase activity|glucosaminyl 3-O-sulfotransferase activity|3-OST-1 activity|heparin-glucosamine 3-O-sulfotransferase activity|heparin-glucosamine 3-O-sulphotransferase activity|3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine 3-sulfotransferase|isoform/isozyme 1 (3-OST-1, HS3ST1) Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate. The [heparan sulfate]-glucosamine 3-sulfate has a substrate consensus sequence of Glc(N2S>NAc)+/-6S GlcA GlcN2S*+/-6S GlcA>IdoA+/-2S Glc(N2S/NAc)+/-6S. GO:0008466 glycogenin glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008466 EC:2.4.1.186|Reactome:R-HSA-3814838|MetaCyc:GLYCOGENIN-GLUCOSYLTRANSFERASE-RXN|Reactome:R-HSA-3322019|Reactome:R-HSA-3322025|Reactome:R-HSA-3322003|Reactome:R-HSA-3322014|RHEA:23360 priming glucosyltransferase activity|1,4alpha-glucan-protein synthase (UDP-forming) activity|alpha-1,4-glucan-protein synthase (UDP-forming) activity|UDP-glucose:glycogenin glucosyltransferase activity|UDP-alpha-D-glucose:glycogenin alpha-D-glucosyltransferase activity|glycogenin activity Catalysis of the reaction: UDP-glucose + glycogenin = UDP + glucosylglycogenin. GO:0008465 glycerate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008465 EC:1.1.1.29|RHEA:17905|MetaCyc:GLYCERATE-DEHYDROGENASE-RXN hydroxypyruvate dehydrogenase activity Catalysis of the reaction: (R)-glycerate + NAD+ = hydroxypyruvate + NADH + H+. CHEBI:83436 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4-phosphate)(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83436 GO:0008464 obsolete gamma-glutamyl hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008464 poly(glutamic acid) hydrolase II|folic acid conjugase activity|conjugase activity|poly(gamma-glutamic acid) endohydrolase activity|pteroyl-poly-alpha-glutamate hydrolase activity|lysosomal gamma-glutamyl carboxypeptidase activity|gamma-Glu-X carboxypeptidase activity|folate conjugase activity|gamma-glutamyl hydrolase activity|carboxypeptidase G activity|polyglutamate hydrolase activity|pteroyl-poly-gamma-glutamate hydrolase activity|pteroylpoly-gamma-glutamyl hydrolase activity OBSOLETE. Catalysis of the cleavage of a gamma-glutamyl bond to release an unsubstituted C-terminal amino acid. CHEBI:83435 3,6-anhydro-L-galactonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83435 GO:0008463 formylmethionine deformylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008463 MetaCyc:FORMYLMETHIONINE-DEFORMYLASE-RXN|KEGG_REACTION:R00653|EC:3.5.1.31|RHEA:17781 N-formyl-L-methionine amidohydrolase activity Catalysis of the reaction: N-formyl-L-methionine + H(2)O = L-methionine + formate. CHEBI:83434 2-hydroxy-5-methyl-1-naphthoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83434 GO:0008462 obsolete endopeptidase Clp activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008462 endopeptidase Ti activity|endopeptidase Clp activity|caseinolytic protease activity|Clp protease|protease Ti activity|ATP-dependent Clp protease|ClpP OBSOLETE. Catalysis of the hydrolysis of proteins to small peptides in the presence of ATP and magnesium. Alpha-casein is the usual test substrate. In the absence of ATP, only oligopeptides shorter than five residues are cleaved, for example, succinyl-Leu-Tyr-NHMec which is cleaved at the Tyr-NHMec bond, and Leu-Tyr-Leu-Tyr-Trp which is cleaved at the second Leu-Typ bond (cleavage of the Tyr-Leu and Tyr-Trp bonds also occurs). CHEBI:83433 3,6-anhydro-alpha-L-galactopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83433 GO:0008461 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008461 GO:0008471 obsolete laccase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008471 p-diphenol oxidase activity|urishiol oxidase activity|urushiol oxidase activity|benzenediol:oxygen oxidoreductase activity|laccase activity OBSOLETE. Catalysis of the reaction: 4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O. CHEBI:83431 [5-(ammoniomethyl)-3-furyl]methyl phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83431 GO:0008470 isovaleryl-CoA dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008470 EC:1.3.8.4|RHEA:12276|Reactome:R-HSA-70745|MetaCyc:ISOVALERYL-COA-FAD-RXN isovaleryl-coenzyme A dehydrogenase activity|isovaleroyl-coenzyme A dehydrogenase activity|3-methylbutanoyl-CoA:(acceptor) oxidoreductase activity|3-methylbutanoyl-CoA:acceptor oxidoreductase activity Catalysis of the reaction: 3-methylbutanoyl-CoA + ETF = 3-methylbut-2-enoyl-CoA + reduced ETF. GO:0033424 CCG codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033424 proline tRNA A triplet codon-amino acid adaptor activity that recognizes a CCG codon. CHEBI:138121 dermatan 4',6'-disulfate anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138121 GO:0033423 CCA codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033423 proline tRNA A triplet codon-amino acid adaptor activity that recognizes a CCA codon. GO:0033422 CCC codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033422 proline tRNA A triplet codon-amino acid adaptor activity that recognizes a CCC codon. GO:0033421 CCU codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033421 CCT codon-amino acid adaptor activity|proline tRNA A triplet codon-amino acid adaptor activity that recognizes a CCU codon. GO:0033420 CUG codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033420 leucine tRNA|CTG codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a CUG codon. GO:0033419 CUA codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033419 CTA codon-amino acid adaptor activity|leucine tRNA A triplet codon-amino acid adaptor activity that recognizes a CUA codon. GO:0033418 CUC codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033418 leucine tRNA|CTC codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a CUC codon. GO:0033417 CUU codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033417 leucine tRNA|CTT codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a CUU codon. CHEBI:138140 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phospholipid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138140 GO:0033416 UGG codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033416 tryptophan tRNA|TGG codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a UGG codon. GO:0033415 UGA codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033415 TGA codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a UGA codon. GO:0033414 UGC codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033414 TGC codon-amino acid adaptor activity|cysteine tRNA A triplet codon-amino acid adaptor activity that recognizes a UGC codon. GO:0008479 queuine tRNA-ribosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008479 Reactome:R-HSA-6782443|RHEA:16633|MetaCyc:QUEUOSINE-TRNA-RIBOSYLTRANSFERASE-RXN|EC:2.4.2.29 transfer ribonucleate glycosyltransferase activity|guanine, queuine-tRNA transglycosylase activity|tRNA-guanine transglycosylase activity|Q-insertase activity|queuine transfer ribonucleate ribosyltransferase activity|[tRNA]-guanine:queuine tRNA-D-ribosyltransferase activity|tRNA guanine transglycosidase activity|guanine insertion enzyme activity|tRNA transglycosylase activity Catalysis of the reaction: tRNA guanine + queuine = tRNA queuine + guanine. GO:0008478 pyridoxal kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008478 MetaCyc:PYRIDOXKIN-RXN|EC:2.7.1.35|RHEA:10224|Reactome:R-HSA-964962|Reactome:R-HSA-964970|Reactome:R-HSA-964958 vitamin B6 kinase activity|ATP:pyridoxal 5'-phosphotransferase activity|pyridoxine kinase activity|pyridoxal 5-phosphate-kinase activity|pyridoxal phosphokinase activity|pyridoxal kinase (phosphorylating)|pyridoxamine kinase activity|vitamin B(6) kinase activity Catalysis of the reaction: ATP + pyridoxal = ADP + pyridoxal 5'-phosphate. GO:0008477 purine nucleosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008477 RHEA:23344|MetaCyc:PURINE-NUCLEOSIDASE-RXN|EC:3.2.2.1 inosine-adenosine-guanosine preferring nucleoside hydrolase activity|ribonucleoside hydrolase activity|nucleoside hydrolase activity|purine ribonucleosidase activity|purine nucleoside hydrolase activity|IAG-NH activity|purine beta-ribosidase activity|purine-specific nucleoside N-ribohydrolase activity|nucleosidase g activity|purine nucleosidase reaction|purine-nucleoside ribohydrolase activity|N-D-ribosylpurine ribohydrolase activity|N-ribosyl purine ribohydrolase activity|nucleosidase activity|IAG-nucleoside hydrolase activity Catalysis of the reaction: a N-D-ribosylpurine + H2O = a purine + D-ribose. GO:0008476 protein-tyrosine sulfotransferase activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0008476 RHEA:16801|EC:2.8.2.20|Reactome:R-HSA-9668023|Reactome:R-HSA-8954262|Reactome:R-HSA-9668148|MetaCyc:PROTEIN-TYROSINE-SULFOTRANSFERASE-RXN tyrosylprotein sulfotransferase activity|protein-tyrosine sulphotransferase activity|3'-phosphoadenylyl-sulfate:protein-tyrosine O-sulfotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + protein tyrosine = adenosine 3',5'-bisphosphate + protein tyrosine-O-sulfate. GO:0008475 procollagen-lysine 5-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008475 RHEA:16569|EC:1.14.11.4|MetaCyc:PROCOLLAGEN-LYSINE-5-DIOXYGENASE-RXN|Reactome:R-HSA-1981104 protocollagen lysyl hydroxylase activity|procollagen-lysine,2-oxoglutarate 5-dioxygenase activity|collagen lysine hydroxylase activity|lysyl hydroxylase activity|lysylprotocollagen dioxygenase activity|lysine hydroxylase activity|lysine-2-oxoglutarate dioxygenase activity|lysine,2-oxoglutarate 5-dioxygenase activity|procollagen-L-lysine,2-oxoglutarate:oxygen oxidoreductase (5-hydroxylating)|protocollagen lysine dioxygenase activity|protocollagen lysine hydroxylase activity Catalysis of the reaction: procollagen L-lysine + 2-oxoglutarate + O2 = procollagen 5-hydroxy-L-lysine + succinate + CO2. GO:0008474 palmitoyl-(protein) hydrolase activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0008474 Reactome:R-HSA-203613|Reactome:R-HSA-9647994|RHEA:19233|MetaCyc:3.1.2.22-RXN|Reactome:R-HSA-8933328|Reactome:R-HSA-5690517|EC:3.1.2.22 palmitoyl-protein thiolesterase activity|palmitoyl-protein hydrolase activity|palmitoyl-[protein] hydrolase|palmitoyl-protein thioesterase activity Catalysis of the reaction: palmitoyl-protein + H2O = palmitate + protein. GO:0008473 ornithine cyclodeaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008473 RHEA:24368|KEGG_REACTION:R00671|MetaCyc:ORNITHINE-CYCLODEAMINASE-RXN|EC:4.3.1.12 ornithine cyclase activity|L-ornithine ammonia-lyase (cyclizing; L-proline-forming)|OCD activity|L-ornithine ammonia-lyase (cyclizing)|ornithine cyclase (deaminating) activity Catalysis of the reaction: L-ornithine = L-proline + NH(4)(+). CHEBI:83444 4-(5-O-phospho-beta-D-ribofuranosyl)phenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83444 GO:0008472 obsolete metallocarboxypeptidase D activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008472 carboxypeptidase D (cattle, human, mouse, rat)|metallocarboxypeptidase D activity|gp180 (duck) OBSOLETE. Catalysis of the reaction: peptidyl-L-lysine (or peptidyl-L-arginine) + H2O = peptide + L-lysine (or L-arginine). Function is activated by Co2+; inhibited by guanidinoethylmercaptosuccinic acid. GO:0008482 sulfite oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008482 MetaCyc:PWY-5326|KEGG_REACTION:R00533|RHEA:24600|Reactome:R-HSA-1614544|MetaCyc:SULFITE-OXIDASE-RXN|EC:1.8.3.1 sulphite oxidase activity|sulfite:oxygen oxidoreductase activity Catalysis of the reaction: H(2)O + O(2) + sulfite = H(2)O(2) + H(+) + sulfate. GO:0008481 sphinganine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008481 RHEA:15465|EC:2.7.1.91|MetaCyc:SPHINGANINE-KINASE-RXN|Reactome:R-HSA-428214 sphingosine kinase (phosphorylating)|dihydrosphingosine kinase activity|ATP:sphinganine 1-phosphotransferase activity|sphingosine kinase activity|dihydrosphingosine kinase (phosphorylating) Catalysis of the reaction: ATP + sphinganine = ADP + sphinganine 1-phosphate. CHEBI:83441 O-[S-(3R)-hydroxyicosanoylpantetheine-4-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83441 GO:0008480 sarcosine dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008480 Reactome:R-HSA-6797913|KEGG_REACTION:R00611|MetaCyc:SARCOSINE-DEHYDROGENASE-RXN|EC:1.5.8.3|RHEA:19793 monomethylglycine dehydrogenase activity|sarcosine:acceptor oxidoreductase (demethylating)|sarcosine:(acceptor) oxidoreductase (demethylating)|sarcosine N-demethylase activity Catalysis of the reaction: sarcosine + H2O + electron-transfer flavoprotein = glycine + formaldehyde + reduced electron-transfer flavoprotein. CHEBI:138139 2,3-bis-O-phytanyl-sn-glycerol 1-phospholipid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138139 CHEBI:83440 O-(S-3-oxoicosanoylpantetheine-4'-phosphoryl)-L-serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83440 CHEBI:138138 epoxy(hydroxy)icosatrienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138138 GO:0033413 UGU codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033413 TGT codon-amino acid adaptor activity|cysteine tRNA A triplet codon-amino acid adaptor activity that recognizes a UGU codon. GO:0033412 UAG codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033412 TAG codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a UAG codon. GO:0033411 UAA codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033411 TAA codon-amino acid adaptor activity A triplet codon-amino acid adaptor activity that recognizes a UAA codon. CHEBI:138131 Delta(5),Delta(7)-sterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138131 CHEBI:138130 Delta(7)-sterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_138130 GO:0033410 UAC codon-amino acid adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033410 TAC codon-amino acid adaptor activity|tyrosine tRNA A triplet codon-amino acid adaptor activity that recognizes a UAC codon. CHEBI:138135 (13S)-hydroxy-(14S,15S)-epoxy-(5Z,8Z,11Z)-icosatrienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_138135 UBERON:3000961 external integument structure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_3000961 Structures of the dermis, epidermis, glands and pigment cells recognizable on the external surfaces of the integument. UBERON:3000981 limb external integument structure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_3000981 Dermal, epidermal, glandular and pigment structures of the limb integument. UBERON:3000977 body external integument structure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_3000977 Dermal, epidermal, glandular and pigment structures of the body integument. UBERON:3000972 head external integument structure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_3000972 Dermal, epidermal, glandular and pigment structures of the external head integument. CHEBI:10417 beta-eudesmol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_10417 CHEBI:10415 beta-endorphin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_10415 CHEBI:10418 trans-beta-farnesene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_10418 UBERON:0001095 caudal vertebra biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001095 caudal vertebrae|caudal vertebral bone|caudal vertebra|caudal vertebral bone element|coccygea|fused tail vertebra|coccygeal segment|tail vertebra|coccygeal vertebra Any vertebral bone that is part of the caudal region of the vertebral column (tail or coccyx). UBERON:0001096 wall of esophagus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001096 esophagus anatomical wall|gullet anatomical wall|wall of oesophagus|anatomical wall of oesophagus|oesophagus wall|esophageal wall|oesophagus anatomical wall|wall of gullet|esophagus wall|gullet wall|anatomical wall of esophagus|anatomical wall of gullet An anatomical wall that is part of a esophagus [Automatically generated definition]. UBERON:0001091 calcareous tooth biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001091 dentine containing tooth|vertebrate tooth|dental element|tooth Skeletal element within the mouth (or in some species, upper part of the digestive tract) that is composed of dentine and is used in procuring or masticating food. UBERON:0001090 synovial fluid biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001090 joint fluid Joint fluid is a transudate of plasma that is actively secreted by synovial cells. UBERON:0001093 vertebral bone 2 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001093 axis|axis vertebra|cervical axis|C2 vertebra|axis (CII)|vertebra 2|second cervical vertebra|cervical vertebra 2|C2|axis [C II] The second vertebral bone in the vertebral column. UBERON:0001092 vertebral bone 1 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001092 first cervical vertebra|atlas [C I]|cervical atlas|atlas vertebra|atlas (CI)|C1 vertebra|vertebra 1|atlas|C1|cervical vertebra 1 The first vertebral bone in the vertebral column. UBERON:3000982 tail external integument structure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_3000982 Dermal, epidermal, glandular and pigment structures of the tail integument. UBERON:0001084 skin of head biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001084 head zone of skin|adult head zone of skin|zone of skin of adult head|head skin|zone of skin of head A zone of skin that is part of a head [Automatically generated definition]. UBERON:0001083 myocardium of ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001083 ventricular myocardium|ventricle cardiac muscle|ventricle myocardium Muscular layer of the cardiac ventricle composed of a compact myocardial layer surrounding the trabecular layer. UBERON:0001085 skin of trunk biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001085 trunk skin|torso zone of skin|trunk zone of skin|zone of skin of trunk|zone of skin of torso A zone of skin that is part of a trunk [Automatically generated definition]. UBERON:0001082 epicardium of ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001082 ventricular epicardium|cardiac ventricle epicardium An epicardial layer that lines a cardiac ventricle UBERON:0001081 endocardium of ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001081 endocardium of ventricle of heart|heart ventricle endocardium|endocardium of heart ventricle|ventricle endocardium|ventricle of heart endocardium|cardiac ventricle endocardium|endocardium of cardiac ventricle|endocardium of lower chamber of heart|ventricle endocardial tissue|ventricular endocardium|lower chamber of heart endocardium Endocardium that is part of the cardiac ventricle. UBERON:0001088 urine biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001088 Excretion that is the output of a kidney UBERON:0001087 pleural fluid biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001087 Transudate contained in the pleural cavity. UBERON:0001089 sweat biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001089 skin exudate Secretion produced by a sweat gland. CHEBI:2651 alpha-aminoacyl-tRNA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_2651 GO:0033394 beta-alanine biosynthetic process via 1,3 diaminopropane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033394 MetaCyc:PWY-3981 beta-alanine formation via 1,3 diaminopropane|beta-alanine synthesis via 1,3 diaminopropane|beta-alanine biosynthesis via 1,3 diaminopropane|beta-alanine anabolism via 1,3 diaminopropane The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 1,3 diaminopropane. GO:0033393 homogalacturonan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033393 MetaCyc:PWY-1081 homogalacturonan degradation|homogalacturonan breakdown|homogalacturonan catabolism The chemical reactions and pathways resulting in the breakdown of homogalacturonan, a pectidic polymer, characterized by a backbone of 1,4-linked alpha-D-GalpA residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3. GO:0033392 obsolete actin homodimerization activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033392 actin homodimerization activity|actin dimerization activity|actin polymerizing activity OBSOLETE. Interacting selectively and non-covalently with an identical actin monomer to form a homodimer. GO:0033391 chromatoid body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033391 A ribonucleoprotein complex found in the cytoplasm of male germ cells, composed of exceedingly thin filaments that are consolidated into a compact mass or into dense strands of varying thickness that branch to form an irregular network. Contains mRNAs, miRNAs, and protein components involved in miRNA processing (such as Argonaute proteins and the endonuclease Dicer) and in RNA decay (such as the decapping enzyme DCP1a and GW182). GO:0033390 putrescine biosynthetic process from arginine via N-carbamoylputrescine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033390 putrescine anabolism from arginine via N-carbamoylputrescine|putrescine synthesis from arginine via N-carbamoylputrescine|putrescine formation from arginine via N-carbamoylputrescine|putrescine biosynthesis from arginine via N-carbamoylputrescine The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine, via the intermediate N-carbamoylputrescine; in this pathway, arginine is converted to agmatine, and agmatine is converted to putrescine in two single enzymatic steps. GO:0033399 cis-zeatin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033399 cis-zeatin metabolism The chemical reactions and pathways involving cis-zeatin, (2Z)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol. GO:0033398 zeatin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033398 zeatin anabolism|zeatin synthesis|zeatin formation|zeatin biosynthesis The chemical reactions and pathways resulting in the formation of zeatin, 2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol. GO:0033397 zeatin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033397 zeatin metabolism The chemical reactions and pathways involving zeatin, 2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol. GO:0033396 beta-alanine biosynthetic process via 3-ureidopropionate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033396 MetaCyc:PWY-3982 beta-alanine formation via 3-ureidopropionate|beta-alanine synthesis via 3-ureidopropionate|beta-alanine anabolism via 3-ureidopropionate The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 3-ureidopropionate. GO:0033395 beta-alanine biosynthetic process via 3-hydroxypropionate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033395 MetaCyc:PWY-3941 beta-alanine anabolism via 3-hydroxypropionate|beta-alanine biosynthesis via 3-hydroxypropionate|beta-alanine synthesis via 3-hydroxypropionate|beta-alanine formation via 3-hydroxypropionate The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 3-hydroxypropionate. CHEBI:2639 amiloride biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_2639 GO:0033383 geranyl diphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033383 geranyldiphosphate metabolic process|geranyl diphosphate metabolism The chemical reactions and pathways involving geranyl diphosphate, the universal precursor of the monoterpenes. GO:0033382 maintenance of granzyme B location in T cell secretory granule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033382 maintenance of granzyme B localization in T-cell secretory granule|maintenance of granzyme B localization in T-lymphocyte secretory granule|maintenance of granzyme B localization in T cell secretory granule|maintenance of granzyme B localization in T lymphocyte secretory granule A process in which the protease granyme B is maintained in a secretory granule in a T cell and prevented from moving elsewhere. GO:0033381 establishment of granzyme B localization to T cell secretory granule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033381 establishment of granzyme B localization in T lymphocyte secretory granule|T-lymphocyte secretory granule storage of granzyme B|establishment of granzyme B localization in T-cell secretory granule|establishment of granzyme B localization in T-lymphocyte secretory granule|establishment of granzyme B localisation in T cell secretory granule|establishment of granzyme B localization in T cell secretory granule The directed movement of the protease granzyme B to a location within a secretory granule in a T cell. GO:0033380 granzyme B localization to T cell secretory granule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033380 granzyme B localization in T lymphocyte secretory granule|granzyme B localization in T-cell secretory granule|granzyme B localization in T-lymphocyte secretory granule|granzyme B localisation in T cell secretory granule|granzyme B localization in T cell secretory granule Any process in which the protease granzyme B is transported to, or maintained in, a location within a secretory granule in a T cell. CHEBI:2634 amidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_2634 GO:0033389 putrescine biosynthetic process from arginine, using agmatinase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033389 putrescine anabolism from arginine, using agmatinase|putrescine synthesis from arginine, using agmatinase|putrescine formation from arginine, using agmatinase|putrescine biosynthesis from arginine, using agmatinase The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine; in this pathway, arginine is converted to agmatine, and agmatine is converted to putrescine in a single enzymatic step. GO:0033388 putrescine biosynthetic process from arginine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033388 putrescine anabolism from arginine|putrescine synthesis from arginine|putrescine formation from arginine|putrescine biosynthesis from arginine The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine. GO:0033387 putrescine biosynthetic process from ornithine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033387 putrescine biosynthesis from ornithine|putrescine formation from ornithine|putrescine synthesis from ornithine|putrescine anabolism from ornithine The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane by decarboxylation of ornithine. GO:0033386 geranylgeranyl diphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033386 MetaCyc:PWY-5121|MetaCyc:PWY-5120 geranylgeranyl diphosphate synthesis|geranylgeranyl diphosphate formation|geranylgeranyl diphosphate biosynthesis|geranylgeranyl diphosphate anabolism The chemical reactions and pathways resulting in the formation of geranylgeranyl diphosphate. GO:0033385 geranylgeranyl diphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033385 geranylgeranyldiphosphate metabolic process|geranylgeranyl diphosphate metabolism The chemical reactions and pathways involving geranylgeranyl diphosphate, a polyprenol compound involved in the biosynthesis of a variety of terpenoids including chlorophylls, carotenoids, tocopherols, plastoquinones, and the plant hormones gibberellins. GO:0033384 geranyl diphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033384 MetaCyc:PWY-5122 geranyldiphosphate biosynthetic process|geranyl diphosphate anabolism|geranyl diphosphate synthesis|geranyl diphosphate biosynthesis|geranyl diphosphate formation The chemical reactions and pathways resulting in the formation of geranyl diphosphate. GO:0033372 establishment of protease localization to mast cell secretory granule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033372 establishment of protease localization in mast cell secretory granule|establishment of protease localisation in mast cell secretory granule The directed movement of a protease to a location within a secretory granule in a mast cell. GO:0033371 T cell secretory granule organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033371 T-cell secretory granule organization|T cell secretory granule organization and biogenesis|T lymphocyte secretory granule organization|T cell secretory granule organisation|T-lymphocyte secretory granule maturation|T-lymphocyte secretory granule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a T cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. GO:0033370 maintenance of protein location in mast cell secretory granule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033370 mast cell protein retention|maintenance of protein localization in mast cell secretory granule A process in which a protein is maintained in a secretory granule in a mast cell and prevented from moving elsewhere. GO:0033379 maintenance of protease location in T cell secretory granule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033379 maintenance of protease localization in T-cell secretory granule|maintenance of protease localization in T-lymphocyte secretory granule|maintenance of protease localization in T cell secretory granule|maintenance of protease localization in T lymphocyte secretory granule A process in which a protease is maintained in a secretory granule in a T cell and prevented from moving elsewhere. GO:0033378 establishment of protease localization to T cell secretory granule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033378 establishment of protease localization in T-cell secretory granule|establishment of protease localization in T-lymphocyte secretory granule|establishment of protease localisation in T cell secretory granule|establishment of protease localization in T cell secretory granule|establishment of protease localization in T lymphocyte secretory granule The directed movement of a protease to a location within a secretory granule in a T cell. GO:0033377 maintenance of protein location in T cell secretory granule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033377 maintenance of protein localization in T-lymphocyte secretory granule|maintenance of protein localization in T cell secretory granule|maintenance of protein localization in T lymphocyte secretory granule|maintenance of protein localization in T-cell secretory granule A process in which a protein is maintained in a secretory granule in a T cell and prevented from moving elsewhere. GO:0033376 establishment of protein localization to T cell secretory granule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033376 establishment of protein localisation in T cell secretory granule|establishment of protein localization in T cell secretory granule|establishment of protein localization in T lymphocyte secretory granule|establishment of protein localization in T-cell secretory granule|establishment of protein localization in T-lymphocyte secretory granule The directed movement of a protein to a location within a secretory granule in a T cell. GO:0033375 protease localization to T cell secretory granule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033375 protease localization in T-cell secretory granule|protease localization in T-lymphocyte secretory granule|protease localisation in T cell secretory granule|protease localization in T cell secretory granule|protease localization in T lymphocyte secretory granule Any process in which a protease is transported to, or maintained in, a location within a secretory granule in a T cell. GO:0033374 protein localization to T cell secretory granule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033374 protein localisation in T cell secretory granule|protein localization in T cell secretory granule|protein localization in T lymphocyte secretory granule|protein localization in T-cell secretory granule|protein localization in T-lymphocyte secretory granule A process in which a protein is transported to, or maintained in, a location within a secretory granule in a T cell. GO:0033373 maintenance of protease location in mast cell secretory granule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033373 maintenance of protease localization in mast cell secretory granule|mast cell protease retention A process in which a protease is maintained in a secretory granule in a mast cell and prevented from moving elsewhere. PO:0020094 plant egg cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0020094 egg cell (broad)|植物卵細胞 (Japanese, exact)|oocélula (Spanish, exact)|female gamete (exact)|megagamete (exact)|non-mobile gamete (broad) A gamete (PO:0025006) produced by an archegonium (PO:0025126) or an embryo sac (PO:0025074). PO:0020093 antipodal cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0020093 célula antipodal (Spanish, exact)|反足細胞 (Japanese, exact) Cell, commonly three in number as in the eight-nucleate embryo sac, located at the other end of the embryo sac from the egg cell. PO:0020096 egg apparatus biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0020096 卵装置 (Japanese, exact)|aparato de la oocélula (Spanish, exact) A cardinal organ part that has as parts an egg cell and two synergids and is located at the micropylar end of the embryo sac. PO:0020090 embryo sac central cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0020090 中央細胞 (Japanese, exact)|célula central (Spanish, exact) An embryo sac cell (PO:0025026) that is largest cell in a mature embryo sac (PO:0025074). CL:3000002 sympathetic noradrenergic neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_3000002 Sympathetic noradrenergic neuron. CHEBI:58419 4-hydroxy-L-proline zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58419 CHEBI:58418 ditrans,polycis-decaprenyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58418 UBERON:0001037 strand of hair biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001037 coat/ hair|hair|quill|fur|coat hair|whisker|setulae|vibrissa|microchaeta A filament, mostly protein, that grows from follicles found in the dermis[WP]. CHEBI:58416 chlorophyll a(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58416 CHEBI:58415 deacetoxycephalosporin C(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58415 CHEBI:58414 1D-myo-inositol 1,3,4-trisphosphate(6-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58414 CL:3000003 sympathetic cholinergic neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_3000003 Sympathetic cholinergic neuron. UBERON:0001033 gustatory system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001033 gustatory organ system|taste system The sensory system for the sense of taste. CHEBI:58413 (R)-6-hydroxynicotinium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58413 UBERON:0001032 sensory system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001032 sensory subsystem|sense organ subsystem|organa sensuum|sensory systems|organa sensuum|sensory organ system|set of sense organs|sense organs set|sense organs Anatomical system that overlaps the nervous system and is responsible for receiving and processing sensory information. CHEBI:58412 syringetin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58412 CHEBI:58411 CoM-S-S-CoB(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58411 CHEBI:58410 2-amino-5-oxocyclohex-1-enecarbonyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58410 UBERON:0001019 nerve fasciculus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001019 fascicle|nerve fasciculus|nerve fiber tract|neural fasciculus|fasciculus|nerve bundle A slender neuron projection bundle[FBbt]; A bundle of anatomical fibers, as of muscle or nerve (American Heritage Dictionary 4th ed). UBERON:0001018 axon tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001018 tract of neuraxis|tract|neuraxis tract|nerve tract|nerve tract|axonal tract A group of axons linking two or more neuropils and having a common origin, termination[FBbt]. CHEBI:58409 alpha-D-mannose 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58409 CHEBI:58408 penicillin N(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58408 CHEBI:58407 isoscoparin-7-olate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58407 UBERON:0001020 nervous system commissure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001020 white matter commissure|neuraxis commissure|commissure of neuraxis|commissure Axon tract that crosses the midline of the central nervous system[NIF, modified]. In the context of Drosophila refers to a broad band of axons connecting equivalent neuropils each side of the brain[FBbt]. CHEBI:58406 4-amino-4-deoxychorismate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58406 CHEBI:58405 ditrans,polycis-undecaprenyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58405 CHEBI:58404 (E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58404 UBERON:0001027 sensory nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001027 afferent nerve|nervus sensorius A nerve that transmits from sensory receptors on the surface of the body to the central nervous system. CHEBI:58403 3,5,3'-triiodothyropyruvate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58403 CHEBI:58402 5-oxo-L-prolinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58402 CHEBI:58401 1D-myo-inositol 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58401 UBERON:0001021 nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001021 neural subtree|nerves|peripheral nerve An enclosed, cable-like bundle of axons in the peripheral nervous system originating in a nerve root in the central nervous system (or a condensed nervous structure) connecting with peripheral structures. CHEBI:58400 2-oxophytanate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58400 CHEBI:34450 5,6-EET biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_34450 UBERON:0001008 renal system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001008 systema urinarium|urinary tract|systema urinaria|renal/urinary system|excretory system|renal system|urinary system|renal or urinary system The renal system in an anatomical system that maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products.. UBERON:0001007 digestive system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001007 gut|alimentary system|alimentary tract|gastrointestinal system Anatomical system that has as its parts the organs devoted to the ingestion, digestion, and assimilation of food and the discharge of residual wastes. UBERON:0001009 circulatory system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001009 systema cardiovasculare organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis[WP]. OBO:GOCHE_50249 substance with anticoagulant role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_50249 UBERON:2001471 posterior lateral line system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_2001471 The posterior lateral line system develops from cranial ectodermal placodes, situated behind the ear, that give rise to both the neuromasts and the posterior lateral line sensory nerves that innervate the neuromasts. The posterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The posterior mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance. UBERON:2001470 anterior lateral line biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_2001470 The anterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The anterior lateral line develops from cranial ectodermal placodes situated between the eye and ear. OBO:GOCHE_50248 substance with hematologic agent role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_50248 UBERON:2001472 anterior lateral line neuromast biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_2001472 neuromast anterior Neuromast that is part of the anterior lateral line. Kimmel et al, 1995. (Also see Anatomical Atlas entry for lateral line by T. Whitfield.) UBERON:2001468 anterior lateral line system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_2001468 The anterior lateral line system develops from cranial ectodermal placodes, situated between the eye and the ear, that give rise to both the neuromasts and the anterior lateral line sensory nerves that innervate the neuromasts. The anterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians and are innervated by several lateral line nerves, which project to the hindbrain. The anterior lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance. CHEBI:2679 amphetamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_2679 UBERON:0001015 musculature biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001015 muscle group|set of skeletal muscles|musculature|musculature system|muscles set|muscles|musculi|muscle system|set of muscles A subdivision of the muscular system corresponding to a subdisivision of an organism. UBERON:0001017 central nervous system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001017 neuraxis|cerebrospinal axis|systema nervosum centrale|CNS The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord. UBERON:0001016 nervous system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001016 nerve net|neurological system|systema nervosum The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO]. UBERON:0001013 adipose tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001013 adipose|bodyfat|fatty depot|fat tissue|fatty tissue|fat Portion of connective tissue composed of adipocytes enmeshed in areolar tissue UBERON:2001457 postcranial axial cartilage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_2001457 Cartilage which is part of the axial skeleton. UBERON:0001004 respiratory system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001004 systema respiratorium|apparatus respiratorius|apparatus respiratorius|Atmungssystem|respiratory system Functional system which consists of structures involved in respiration. UBERON:0001003 skin epidermis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001003 epidermis|skin|vertebrate epidermis The outer epithelial layer of the skin that is superficial to the dermis. UBERON:0001005 respiratory airway biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001005 airways|airway An airway through which respiratory air passes in organisms. UBERON:0001000 vas deferens biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001000 vas deferen|sperm duct|ductus deferens|vasa deferentia|deferent duct A secretory duct that transports sperm from the testis. In mammals this is a continuation of the epididymis and ends in the prostatic urethra where it terminates to form ejaculatory duct UBERON:0001002 cuticle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001002 cuticula|cuticular exoskeleton tough but flexible, non-mineral outer coverings of an organism, or parts of an organism, that provide protection. Cuticles are non-homologous, differing in their origin, structure and chemical composition[WP]. UBERON:0001001 chitin-based cuticle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001001 exoskeleton|cuticle|insect cuticle|arthropod cuticle|arthropod exoskeleton A cuticular covering that is composed primarily of chitin. The main structural component of arthropod cuticle is a polysaccharide, chitin, composed of N-acetylglucosamine units, together with proteins and lipids[WP]. CHEBI:10436 beta-ocimene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_10436 UBERON:0001073 ileocecal junction biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001073 ileocaecal junction A point along the course of the gastrointestinal tract where the small intestine (ileum) ends as it opens into the cecal portion of the large intestine; occurs usually within the iliac fossa, demarcated internally as the ileocecal orifice UBERON:0001072 posterior vena cava biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001072 posterior vena cava|inferior vena cava|postcava|caudal vena cava|inferior caval vein|vena cava inferior A vein that carries deoxygenated blood from the lower half of the body into the right atrium of the heart. UBERON:0001074 pericardial cavity biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001074 pericardial space|cavitas pericardiaca|cavity of pericardial sac A potential space between the visceral and parietal layers of the pericardium. UBERON:0001071 superficial cervical artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001071 superficial branch of transverse cervical artery It ascends beneath the anterior margin of the trapezius, distributing branches to it, and to the neighboring muscles and lymph glands in the neck, and anastomosing with the superficial branch of the descending branch of the occipital artery. UBERON:0001070 external carotid artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001070 external carotid|arteria carotis externa A terminal branch of the left or right common carotid artery which supplies oxygenated blood to to the throat, neck glands, tongue, face, mouth, ear, scalp and dura mater of the meninges[MP] UBERON:0001077 transverse process of vertebra biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001077 processus transversus|vertebra transverse process|transverse process|diapophyses|diapophysis|processus transversus vertebrae The transverse or costal processes of a vertebra, two in number, project one at either side from the point where the lamina joins the pedicle, between the superior and inferior articular processes. They serve for the attachment of muscles and ligaments. [WP,unvetted]. UBERON:0001076 neural spine biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001076 spine of verterba|spinous process of vertebra|processus spinosus vertebrae|neuracanthe@fr|neural spine|vertebra spinous process|processus spinosus|spinous process|épine neurale@fr|neural spines A extension of a neural arches dorsal to the neural canal[TAO,modified]. UBERON:0001062 anatomical entity biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001062 Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species. UBERON:0001064 ventral pancreatic duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001064 main pancreatic duct|canal of Wirsung|pancreatic duct|duct of Wirsung|hepaticopancreatic duct|ductus pancreatis ventralis|chief pancreatic duct A duct joining the pancreas to the common bile duct to supply pancreatic juices which aid in digestion provided by the exocrine pancreas. The pancreatic duct joins the common bile duct just prior to the ampulla of Vater, after which both ducts perforate the medial side of the second portion of the duodenum at the major duodenal papilla. UBERON:0001068 skin of back biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001068 back skin|skin, dorsal region|back zone of skin|zone of skin of back A zone of skin that is part of a back [Automatically generated definition]. UBERON:0001052 rectum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001052 intestinum rectum|rectal sac|terminal portion of intestine|terminal portion of large intestine the terminal portion of the intestinal tube, terminating with the anus UBERON:0001058 mushroom body biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001058 corpora pedunculata|mushroom bodies|corps pédonculés@fr Prominent lobed neuropils found in annelids and all arthropods except crustaceans. They are thought to be involved in olfactory associative learning and memory[MESH] Mushroom body neuropils are divided into calyces, pedunculus, and its subsequent lobes. In Drosophila these are the alpha, beta, and gamma lobes. UBERON:0001054 Malpighian tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001054 Malpighian tube|Malphigian tube|tuba Malpighii A tubule that extends from the posterior part of the digestive tract which absorbs solutes, water, and wastes from the surrounding hemolymph. Each tubule consists of a single layer of cells that is closed off at the distal end with the proximal end joining the alimentary canal at the junction between the midgut and hindgut[WP,modified]. UBERON:0001040 yolk sac biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001040 saccus vitellinus|vesicula umbilicalis A sac-like expansion of the ventral wall of the intestine, narrowed into a yolk stalk near the body[Hyman's]. Membranous sac attached to an embryo, providing early nourishment in the form of yolk in bony fishes, sharks, reptiles, birds, and primitive mammals. It functions as the developmental circulatory system of the human embryo, before internal circulation begins. In the mouse, the yolk sac is the first site of blood formation, generating primitive macrophages and erythrocytes[WP]. CHEBI:10440 (-)-beta-santalene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_10440 UBERON:0001042 chordate pharynx biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001042 pharynx A portion of the respiratory and digestive tracts; its distal limit is the superior part of the esophagus and it connects the nasal and oral cavities with the esophagus and larynx; it contains the valleculae and the pyriform recesses; its upper limits are the nasal cavity and cranial base.[FEED]. UBERON:0001041 foregut biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001041 praeenteron|proenteron Anterior subdivision of a digestive tract. CHEBI:10443 (+)-beta-selinene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_10443 UBERON:0001048 primordium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001048 future organ|primordia|placode|bud|rudiment Primordia are populations of contiguous cells that are morphologically distinct and already correspond in extent to a later organ/tissue[FBbt, Hartenstein, V. (2004)]. UBERON:0001049 neural tube biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001049 presumptive central nervous system|tubus neuralis|neural primordium In the developing vertebrate, the neural tube is the embryo's precursor to the central nervous system, which comprises the brain and spinal cord. The neural groove gradually deepens as the neural folds become elevated, and ultimately the folds meet and coalesce in the middle line and convert the groove into a closed tube, the neural tube or neural canal (which strictly speaking is the center of the neural tube), the ectodermal wall of which forms the rudiment of the nervous system. [WP,unvetted]. UBERON:0001044 saliva-secreting gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001044 salivary gland|glandulae salivariae saliva-secreting exocrine glands of the oral cavity[GO] UBERON:0001043 esophagus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001043 oesophagus|gullet Tube that connects the pharynx to the stomach. In mammals, the oesophagus connects the buccal cavity with the stomach. The stratified squamous non-keratinised epithelium lining the buccal cavity is continued through the pharynx down into the oesophagus. The lowest part of the oesophagus (ca. 2 cm) is lined with gastric mucosa and covered by peritoneum. The main body of the oesophagus is lined with small, simple mucous glands. Each gland opens into the lumen by a long duct which pierces the muscularis mucosae (Wilson and Washington, 1989). A sphincter is situated at the point where the oesophagus enters the stomach to prevent gastro-oesophageal reflux, i.e. to prevent acidic gastric contents from reaching stratified epithelia of the oesophagus, where they can cause inflammation and irritation (Wilson and Washington, 1989; Brown et al., 1993). PO:0020097 generative cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0020097 célula generativa (Spanish, exact)|雄原細胞、生殖系列細胞 (Japanese, exact) A spermatogenous cell (PO:0025525) of the microgametophyte (PO:0025280) that divides to produce two pollen sperm cells (PO:0025121). UBERON:0001046 hindgut biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001046 metenteron The caudalmost subdivision of a digestive tract. UBERON:0001045 midgut biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0001045 mesenteron Middle subdivision of a digestive tract[CJM]. In vertebrates: The middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine[GO]. PO:0020099 microgametophyte vegetative cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0020099 célula vegetativa (Spanish, exact)|tube cell (related)|栄養細胞 (Japanese, exact) A native plant cell (PO:0025606) that is the larger cell of a microgametophyte (PO:0025280) in seed plants. It does not divide further and develops into a pollen tube cell (PO:0025195). UBERON:0005908 conjunctival sac biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005908 subbrillar sac|conjunctiva serous sac A serous sac which is the aggregate of the conjunctiva plus the conjunctival space GO:0033529 raffinose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033529 raffinose synthesis|raffinose biosynthesis|raffinose formation|raffinose anabolism The chemical reactions and pathways resulting in the formation of raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside. GO:0033528 S-methylmethionine cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033528 MetaCyc:PWY-5441 A cyclic series of interconversions involving S-methyl-L-methionine, S-adenosyl-L-homocysteine, S-adenosyl-L-methionine, L-homocysteine, and L-methionine. Converts the methionine group of adenosylmethionine back to free methionine, and may serve regulate the cellular adenosylmethionine level. UBERON:0005906 serous sac biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005906 Organ with organ cavity, which has as parts a serous membrane and a serous cavity . Examples: pleural sac, pericardial sac, tendon sheath, bursa.[FMA] GO:0033527 tetrapyrrole biosynthetic process from glycine and succinyl-CoA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033527 MetaCyc:PWY-5189 tetrapyrrole anabolism from glycine and succinyl-CoA|tetrapyrrole synthesis from glycine and succinyl-CoA|tetrapyrrole biosynthesis from glycine and succinyl-CoA|tetrapyrrole formation from glycine and succinyl-CoA The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next, from other compounds, including glycine and succinyl-CoA. GO:0033526 tetrapyrrole biosynthetic process from glutamate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033526 MetaCyc:PWY-5188 tetrapyrrole formation from glutamate|tetrapyrrole biosynthesis from glutamate|tetrapyrrole synthesis from glutamate|tetrapyrrole anabolism from glutamate The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next, from other compounds, including L-glutamate. UBERON:0005904 duct of male reproductive system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005904 Any of the ducts that are part of a male reproductive system. UBERON:0005903 duct of seminal vesicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005903 ductus excretorius glandulae vesiculosae|excretory duct of seminal gland|ductus excretorius (vesicula seminalis)|seminal vesicle duct|ductus excretorius glandulae vesiculosae Each seminal vesicle consists of a single tube, coiled upon itself, and giving off several irregular cecal diverticula; the separate coils, as well as the diverticula, are connected together by fibrous tissue. When uncoiled, the tube is about the diameter of a quill, and varies in length from 10 to 15 cm.; it ends posteriorly in a cul-de-sac; its anterior extremity becomes constricted into a narrow straight duct called the excretory duct of seminal gland (or duct of the seminal vesicle), which joins with the corresponding ductus deferens to form the ejaculatory duct[WP]. GO:0033525 sinapate ester biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033525 MetaCyc:PWY-3301 sinapate ester anabolism|sinapate ester synthesis|sinapate ester formation|sinapate ester biosynthesis The chemical reactions and pathways resulting in the formation of ester derivates of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate. GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008569 MetaCyc:3.6.4.5-RXN|EC:5.6.1.4 minus-end-directed kinesin ATPase activity|kinesin ATP phosphohydrolase (minus-end-directed)|minus-end-directed microtubule motor activity|minus-end-directed ATP-dependent microtubule motor activity|ATP-dependent minus-end-directed microtubule motor activity Catalysis of movement along a microtubule toward the minus end, coupled to the hydrolysis of ATP. PR:000020226 islet amyloid polypeptide proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000020226 IAPP/ClvPrd An islet amyloid polypeptide that has been processed by proteolytic cleavage. GO:0008568 microtubule-severing ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008568 Reactome:R-HSA-9668419|MetaCyc:3.6.4.3-RXN|EC:5.6.1.1 ATP phosphohydrolase (tubulin-dimerizing)|katanin activity Catalysis of the reaction: ATP + H2O = ADP + phosphate. Catalysis of the severing of a microtubule at a specific spot along its length, coupled to the hydrolysis of ATP. GO:0033524 sinapate ester metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033524 sinapate ester metabolism The chemical reactions and pathways involving ester derivatives of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate. UBERON:0005902 occipital region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005902 basicranial region|occipital region of head|occipital part of head|back of head Anatomical cluster that is located in the posterior region of the cranium and forms the margin of the foramen magnum and occipital condyles. GO:0008567 obsolete dynein ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008567 dynein ATPase activity OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP by dynein that provides the energy for the movement of organelles (endosomes, lysosomes, mitochondria) along microtubules to the centrosome. GO:0008566 mitochondrial protein-transporting ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008566 EC:7.4.2.3|MetaCyc:3.6.3.51-RXN ATPase-coupled mitochondrial protein transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the mitochondrion via the mitochondrial inner membrane translocase complex. GO:0008565 obsolete protein transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008565 secretin|holin|enzyme transporter activity|protein transport chaperone OBSOLETE. Enables the directed movement of proteins into, out of or within a cell, or between cells. GO:0008564 protein-exporting ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008564 EC:7.4.2.8|MetaCyc:3.6.3.50-RXN ATPase-coupled protein transporter activity|ATP phosphohydrolase (protein-secreting)|protein-secreting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins. GO:0008563 obsolete alpha-factor sex pheromone exporter biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008563 alpha-factor-transporting ATPase|alpha-factor sex pheromone exporter OBSOLETE. Catalysis of the reaction: ATP + H2O + alpha-factor(in) = ADP + phosphate + alpha-factor(out). The export of the alpha-factor sex pheromone by an ABC-type (ATP-binding cassette-type) ATPase, characterized by the presence of two similar ATP-binding domains, that does not undergo phosphorylation during the transport process. CHEBI:83336 14-HPDHE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83336 GO:0008562 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008562 CHEBI:83334 12-HPE(8,10,14)TrE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83334 GO:0008561 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008561 GO:0008560 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008560 CHEBI:58376 CMP-N-glycoloyl-beta-neuraminate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58376 GO:0008570 obsolete myosin ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008570 myosin ATPase activity OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP by myosin that provides the energy for actomyosin contraction. CHEBI:58375 trans-4-hydroxy-L-proline zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58375 CHEBI:58374 3-ammoniopropanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58374 CHEBI:58373 3-hexaprenyl-4,5-dihydroxybenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58373 CHEBI:58372 5-oxo-2,5-dihydro-2-furylacetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58372 CHEBI:58371 2-dehydro-3-deoxy-L-rhamnonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58371 CHEBI:58370 dTTP(3-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58370 GO:0033523 histone H2B ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033523 The modification of histone H2B by addition of ubiquitin groups. UBERON:0005911 endo-epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005911 endoepithelium|endoderm-derived epithelium Epithelium that derives from the endoderm. Examples: urothelium, transitional epithelium of ureter, epithelium of prostatic gland.[FMA] GO:0033522 histone H2A ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033522 The modification of histone H2A by addition of one or more ubiquitin groups. GO:0033521 phytyl diphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033521 MetaCyc:PWY-5063 phytyl diphosphate anabolism|phytyl diphosphate synthesis|phytyl diphosphate formation|phytyl diphosphate biosynthesis The chemical reactions and pathways resulting in the formation of phytyl diphosphate, (2E)-3,7,11,15-tetramethylhexadec-2-en-1-yl trihydrogen diphosphate. GO:0033520 phytol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033520 phytol biosynthesis|phytol anabolism|phytol synthesis|phytol formation The chemical reactions and pathways resulting in the formation of phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol. CHEBI:58379 deacetylipecoside(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58379 CHEBI:58378 2-dehydro-3-deoxy-D-fuconate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58378 CHEBI:58377 L-tyrosine methyl ester 4-sulfate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58377 GO:0033519 phytyl diphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033519 phytyl diphosphate metabolism The chemical reactions and pathways involving phytyl diphosphate, (2E)-3,7,11,15-tetramethylhexadec-2-en-1-yl trihydrogen diphosphate. GO:0033518 myo-inositol hexakisphosphate dephosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033518 MetaCyc:PWY-4702|MetaCyc:PWY-4781 phytate dephosphorylation The process of removing one or more phosphate group from myo-inositol hexakisphosphate. GO:0033517 myo-inositol hexakisphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033517 myo-inositol hexakisphosphate metabolism|phytate metabolism|phytate metabolic process The chemical reactions and pathways involving phytic acid, myo-inositol hexakisphosphate, a regulator of intracellular signaling, a highly abundant animal anti-nutrient and a phosphate and mineral storage compound in plant seeds. GO:0033516 L-methionine biosynthetic process from homoserine via O-phospho-L-homoserine and cystathionine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033516 MetaCyc:PWY-702 methionine biosynthetic process from homoserine via O-phospho-L-homoserine and cystathionine|L-methionine formation from homoserine via O-phospho-L-homoserine and cystathionine|L-methionine synthesis from homoserine via O-phospho-L-homoserine and cystathionine|L-methionine anabolism from homoserine via O-phospho-L-homoserine and cystathionine The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including homoserine, via the intermediates O-phospho-L-homoserine and cystathionine. GO:0033515 L-lysine catabolic process using lysine 6-aminotransferase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033515 MetaCyc:PWY-5298 L-lysine degradation using lysine 6-aminotransferase|L-lysine breakdown using lysine 6-aminotransferase The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including alpha-aminoadipate; in this pathway, L-lysine is converted to 2-aminoadipate-6-semialdehyde by lysine 6-aminotransferase. GO:0033514 L-lysine catabolic process to acetyl-CoA via L-pipecolate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033514 MetaCyc:PWY-5283 L-lysine breakdown to acetyl-CoA via L-pipecolate|L-lysine degradation to acetyl-CoA via L-pipecolate The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate L-pipecolate. GO:0008579 JUN kinase phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008579 Catalysis of the reaction: JUN kinase serine/threonine/tyrosine phosphate + H2O = JUN kinase serine/threonine/tyrosine + phosphate. GO:0033513 L-lysine catabolic process to acetyl-CoA via 5-aminopentanamide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033513 MetaCyc:PWY-5280 L-lysine degradation to acetyl-CoA via 5-aminopentanamide|L-lysine breakdown to acetyl-CoA via 5-aminopentanamide The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate 5-aminopentanamide. GO:0008578 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008578 GO:0008577 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008577 GO:0008576 obsolete vesicle-fusing ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008576 vesicle-fusing ATPase activity OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP by an AAA-ATPase, involved in the heterotypic fusion of membrane vesicles with target membranes and the homotypic fusion of various membrane compartments. CHEBI:83349 divinyl chlorophyllide a(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83349 GO:0008575 obsolete proteasome ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008575 proteasome ATPase activity OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP for channel gating and polypeptide unfolding before proteolysis in the proteasome. Six ATPase subunits are present in the regulatory particle (RP) of 26S proteasome. CHEBI:83348 chlorophyllide a(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83348 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008574 MetaCyc:3.6.4.4-RXN|EC:5.6.1.3 kinesin ATP phosphohydrolase (plus-end-directed)|plus-end-directed microtubule motor activity|kinesin activity|plus-end-directed ATP-dependent microtubule motor activity|ATP-dependent plus-end-directed microtubule motor activity|plus-end-directed kinesin ATPase activity Catalysis of movement along a microtubule toward the plus end, coupled to the hydrolysis of ATP. CHEBI:83347 organosulfonic ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83347 GO:0008573 obsolete peroxisome-assembly ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008573 peroxisome-assembly ATPase activity OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. ATP hydrolysis to import and assemble peroxisome components into the organelle. GO:0008572 obsolete nucleoplasmin ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008572 nucleoplasmin ATPase activity OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP required for the ATP-dependent assembly of nucleosome cores, in decondensation of sperm chromatin and in other histone-involving processes. GO:0008571 obsolete non-chaperonin molecular chaperone ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008571 non-chaperonin molecular chaperone ATPase activity OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. This is a highly diverse group of enzymes that perform many functions that are similar to those of chaperonins. They comprise a number of heat-shock-cognate proteins. They are also active in clathrin uncoating and in the oligomerization of actin. CHEBI:83344 8-HPETE methyl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83344 GO:0008581 obsolete ubiquitin-specific protease 5 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008581 ubiquitin isopeptidase T activity|ubiquitin-specific protease 5 activity OBSOLETE. Catalysis of the hydrolysis of the Gly76-Lys48 isopeptide bond of polyubiquitin. CHEBI:83343 12(R)-HETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83343 CHEBI:58365 4-guanidiniumylbutanamide(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58365 GO:0008580 obsolete cytoskeletal regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008580 cytoskeletal regulator activity OBSOLETE. (Was not defined before being made obsolete). CHEBI:83342 10-HPO(6,8,12)TrE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83342 CHEBI:58363 oxamate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58363 CHEBI:58361 diphthinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58361 CHEBI:58360 1-aminocyclopropanecarboxylic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58360 OBO:D96882F1-8709-49AB-BCA9-772A67EA6C33 alobate nucleus biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/D96882F1-8709-49AB-BCA9-772A67EA6C33 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033512 MetaCyc:LYSINE-DEG1-PWY L-lysine breakdown to acetyl-CoA via saccharopine|L-lysine degradation to acetyl-CoA via saccharopine The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate saccharopine. GO:0033511 luteolin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033511 MetaCyc:PWY-5060 luteolin biosynthesis|luteolin synthesis|luteolin formation|luteolin anabolism The chemical reactions and pathways resulting in the formation of luteolin, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one. GO:0033510 luteolin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033510 luteolin metabolism The chemical reactions and pathways involving luteolin, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one. CHEBI:58369 dTDP(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58369 OBO:GOCHE_25442 substance with mycotoxin role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_25442 CHEBI:58367 UDP-D-glucose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58367 CHEBI:58366 deacetylcephalosporin C(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58366 GO:0033509 glutamate catabolic process to propionate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033509 MetaCyc:PWY-5088 glutamate degradation to propionate|glutamate breakdown to propionate The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including propionate. GO:0033508 glutamate catabolic process to butyrate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033508 MetaCyc:PWY-5087 glutamate degradation to butyrate|glutamate breakdown to butyrate The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including butyrate. GO:0033507 glucosinolate biosynthetic process from phenylalanine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033507 MetaCyc:PWY-2821 glucosinolate formation from phenylalanine|glucosinolate synthesis from phenylalanine|glucosinolate anabolism from phenylalanine|glucosinolate biosynthesis from phenylalanine The chemical reactions and pathways resulting in the formation of glucosinolates from other compounds including phenylalanine. GO:0033506 glucosinolate biosynthetic process from homomethionine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033506 MetaCyc:PWY-1187 glucosinolate biosynthesis from homomethionine|glucosinolate anabolism from homomethionine|glucosinolate synthesis from homomethionine|glucosinolate formation from homomethionine The chemical reactions and pathways resulting in the formation of glucosinolates from other compounds including homomethionine. GO:0008549 obsolete dynamin GTPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008549 dynamine GTPase activity|dynamin GTPase activity OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. An enzyme that is involved in endocytosis and is instrumental in pinching off membrane vesicles. GO:0033505 floor plate morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033505 The process in which the anatomical structure of the floor plate is generated and organized. GO:0033504 floor plate development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033504 The progression of the floor plate over time from its initial formation until its mature state. GO:0008548 obsolete signal-recognition-particle GTPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008548 signal-recognition-particle GTPase activity OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. Activity is associated with the signal-recognition particle, a protein and RNA-containing structure involved in endoplasmic reticulum-associated protein synthesis. GO:0008547 obsolete protein-synthesizing GTPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008547 protein-synthesizing GTPase activity OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. A GTPase involved in protein synthesis. In the initiation factor complex, it is IF-2b (98 kDa) that binds GTP and subsequently hydrolyzes it in prokaryotes. In eukaryotes, it is eIF-2 (150 kDa) that binds GTP. In the elongation phase, the GTP-hydrolyzing proteins are the EF-Tu polypeptide of the prokaryotic transfer factor (43 kDa), the eukaryotic elongation factor EF-1a (53 kDa), the prokaryotic EF-G (77 kDa), the eukaryotic EF-2 (70-110 kDa) and the signal recognition particle that play a role in endoplasmic reticulum protein synthesis (325 kDa). EF-Tu and EF1a catalyze binding of aminoacyl-tRNA to the ribosomal A-site, while EF-G and EF-2 catalyze the translocation of peptidyl-tRNA from the A-site to the P-site. GTPase activity is also involved in polypeptide release from the ribosome with the aid of the pRFs and eRFs. GO:0033503 HULC complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033503 A ubiquitin-conjugating enzyme complex that contains two RING finger proteins, which have ubiquitin ligase activity, in addition to a protein with ubiquitin-conjugating enzyme activity; catalyzes the ubiquitination of histone H2B at lysine 119 (or the equivalent residue). In Schizosaccharomyces the subunits are Rhp1, Brl2/Rfp1 and Brl1/Rfp2. GO:0008546 obsolete microtubule/chromatin interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008546 microtubule/chromatin interaction OBSOLETE. Physical interaction between microtubules and chromatin via DNA binding proteins. GO:0033502 cellular galactose homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033502 cell galactose homeostasis A cellular homeostatic process involved in the maintenance of an internal steady state of galactose within a cell or between a cell and its external environment. GO:0008545 JUN kinase kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008545 Reactome:R-HSA-168162 JNKK Catalysis of the phosphorylation of tyrosine and threonine residues in a c-Jun NH2-terminal kinase (JNK), a member of a subgroup of mitogen-activated protein kinases (MAPKs), which signal in response to cytokines and exposure to environmental stress. JUN kinase kinase (JNKK) is a dual-specificity protein kinase kinase and requires activation by a serine/threonine kinase JUN kinase kinase kinase. GO:0008544 epidermis development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008544 hypodermis development The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species. GO:0008543 fibroblast growth factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008543 FGF receptor signalling pathway|FGFR signaling pathway|fibroblast growth factor receptor signalling pathway|FGF receptor signaling pathway The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands. GO:0008542 visual learning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008542 spatial learning Any process in an organism in which a change in behavior of an individual occurs in response to repeated exposure to a visual cue. CHEBI:83358 N-stearoylsphingosine-1-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83358 GO:0008541 proteasome regulatory particle, lid subcomplex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0008541 The subcomplex of the proteasome regulatory particle that forms the peripheral lid, which is added on top of the base subcomplex. CHEBI:83357 7(1)-hydroxychlorophyllide a(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83357 GO:0008540 proteasome regulatory particle, base subcomplex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0008540 The subcomplex of the proteasome regulatory particle that directly associates with the proteasome core complex. CHEBI:83356 chlorophyllide b(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83356 CHEBI:58354 4-amino-2-methyl-5-phosphonatooxymethylpyrimidine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58354 CHEBI:58353 quercetin-7-olate 3,4'-bissulfate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58353 CHEBI:58352 2-hydroxypropyl phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58352 PR:000010877 myogenin biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000010877 MYF4|bHLHc3|class C basic helix-loop-helix protein 3|MYOD1-related protein|MYOG|Myf-4|myogenic factor 4 A protein that is a translation product of the human MYOG gene or a 1:1 ortholog thereof. CHEBI:58351 sirohydrochlorin(8-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58351 CHEBI:83350 protochlorophyllide(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83350 UBERON:2001626 premaxillary tooth biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_2001626 Tooth that is attached to the premaxilla. GO:0033501 galactose homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033501 A homeostatic process involved in the maintenance of an internal steady state of galactose within an organism or cell. GO:0033500 carbohydrate homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033500 A homeostatic process involved in the maintenance of an internal steady state of a carbohydrate within an organism or cell. CHEBI:58359 L-glutamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58359 CHEBI:58358 4-carboxy-2-hydroxy-cis,cis-muconate 6-semialdehyde(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58358 CHEBI:58357 erythro-5-hydroxy-L-lysinium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58357 CHEBI:58356 N-phosphonato-L-lombricine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58356 CHEBI:58355 GDP-L-galactose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58355 GO:0008559 ABC-type xenobiotic transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008559 MetaCyc:3.6.3.44-RXN|EC:7.6.2.2 pleiotropic-drug-resistance protein|PDR protein|xenobiotic transmembrane transporting ATPase activity|P-glycoprotein|MDR protein|multidrug resistance exporter|ATP-dependent xenobiotic transmembrane transporter activity|ATPase-coupled xenobiotic transmembrane transporter activity|xenobiotic ABC transporter|ATP phosphohydrolase (xenobiotic-exporting)|multidrug-resistance protein Catalysis of the reaction: ATP + H2O + xenobiotic(in) = ADP + phosphate + xenobiotic(out). GO:0008558 ABC-type guanine transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008558 MetaCyc:3.6.3.37-RXN|RHEA:20832|EC:7.6.2.6 ATPase-coupled guanine transmembrane transporter activity|ATP-dependent guanine transmembrane transporter activity|guanine ABC transporter|guanine-transporting ATPase activity Catalyses the reaction: ATP + H2O + guanine(out) = ADP + phosphate + guanine(in). GO:0008557 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008557 GO:0008556 potassium transmembrane transporter activity, phosphorylative mechanism biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008556 EC:7.2.2.6|RHEA:16777 potassium-uptake-ATPase activity|K(+)-transporting ATPase activity|K+-transporting ATPase activity|potassium transporting ATPase activity|ATP-dependent potassium transmembrane transporter activity|ATPase-coupled potassium transmembrane transporter activity|ATP phosphohydrolase (K+-importing)|potassium ABC transporter|K(+)-importing ATPase activity|K+-importing ATPase activity|potassium-transporting ATPase activity|potassium-importing ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + K+(out) = ADP + phosphate + K+(in). GO:0008555 ATPase-coupled chloride transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008555 MetaCyc:3.6.3.11-RXN|EC:3.6.3.11 Cl(-)-transporting ATPase activity|chloride-translocating ATPase activity|chloride-transporting ATPase activity|ATP phosphohydrolase (Cl--importing)|chloride ABC transporter|Cl--transporting ATPase activity|chloride transporting ATPase activity|chloride-motive ATPase activity|ATP-dependent chloride transmembrane transporter activity|Cl--motive ATPase activity|Cl--translocating ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cl-(out) = ADP + phosphate + Cl-(in). GO:0008554 P-type sodium transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008554 MetaCyc:3.6.3.7-RXN|RHEA:14633|EC:7.2.2.3 sodium transport ATPase activity|sodium exporting ATPase activity, phosphorylative mechanism|sodium transmembrane transporter activity, phosphorylative mechanism|hydrogen-/sodium-translocating ATPase activity|sodium-exporting ATPase activity|sodium-translocating P-type ATPase activity|Na+-exporting ATPase activity|Na(+)-exporting ATPase activity|sodium-exporting ATPase activity, phosphorylative mechanism|Na+-transporting ATPase activity|Na(+)-transporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) -> ADP + phosphate + Na+(out); by a phosphorylative mechanism. GO:0008553 proton-exporting ATPase activity, phosphorylative mechanism biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008553 EC:7.1.2.1|MetaCyc:3.6.3.6-RXN|RHEA:20852 proton-transporting ATPase activity|H+-exporting ATPase activity|H(+)-transporting ATPase activity|P-type H(+)-exporting ATPase activity|hydrogen-exporting ATPase activity, phosphorylative mechanism|hydrogen-/sodium-translocating ATPase activity|hydrogen exporting ATPase activity, phosphorylative mechanism|H+-transporting ATPase|proton-exporting ATPase activity|proton-translocating ATPase activity|proton transport ATPase activity|hydrogen-exporting ATPase activity Enables the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) -> ADP + phosphate + H+(out). These transporters use a phosphorylative mechanism, which have a phosphorylated intermediate state during the ion transport cycle. GO:0008552 obsolete zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008552 zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity OBSOLETE. Catalysis of the reaction: Me2+(in) + ATP = Me2+(out) + ADP + phosphate, where Me is Zn2+, Cd2+, Co2+, Ni2+ or Pb2+. GO:0008551 P-type cadmium transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008551 MetaCyc:3.6.3.3-RXN|EC:7.2.2.21|RHEA:12132 Cd(2+)-exporting ATPase activity|cadmium exporting ATPase activity|cadmium-exporting ATPase activity|cadmium transmembrane transporter activity, phosphorylative mechanism|Cd2+-exporting ATPase activity|cadmium-translocating P-type ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cd2+(in) -> ADP + phosphate + Cd2+(out). GO:0008550 obsolete tubulin GTPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008550 tubulin GTPase activity OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. An intrinsic activity of alpha-tubulin involved in tubulin folding, division plane formation in prokaryotic cells and others. CHEBI:58343 adenosine 3',5'-bismonophosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58343 CHEBI:58342 acyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58342 CHEBI:58341 UDP-L-arabinose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58341 CHEBI:58340 O-acetyl-L-serine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58340 CHEBI:83360 N-lignoceroylsphingosine-1-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83360 PR:000010882 myozenin-1 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000010882 protein FATZ|MYOZ1|calsarcin-2|MYOZ|filamin-, actinin- and telethonin-binding protein A protein that is a translation product of the human MYOZ1 gene or a 1:1 ortholog thereof. CHEBI:58349 NADP(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58349 CHEBI:58348 3-[hydroxy(oxido)phosphoranyl]pyruvate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58348 CHEBI:58346 2-hydroxy-3-(3-oxoprop-1-enyl)but-2-enedioate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58346 CHEBI:58345 D-ribose 1,5-bisphosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58345 CHEBI:58344 3-(3,4-dioxidopyridinium-1-yl)-L-alanine(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58344 GO:0008529 obsolete endogenous peptide receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008529 endogenous peptide receptor activity OBSOLETE. Combining with an intracellular peptide to initiate a change in cell activity. GO:0008528 G protein-coupled peptide receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008528 peptide receptor activity, G-protein coupled|peptide receptor activity, G protein coupled|G protein coupled peptide receptor activity|G-protein coupled peptide receptor activity Combining with a peptide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. GO:0008527 taste receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008527 gustatory receptor Combining with soluble compounds to initiate a change in cell activity. These receptors are responsible for the sense of taste. PR:000020267 insulin-like growth factor II proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000020267 IGF2/ClvPrd An insulin-like growth factor II that has been processed by proteolytic cleavage. GO:0008526 phosphatidylinositol transfer activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008526 Reactome:R-HSA-8874470|Reactome:R-HSA-8869241 intermembrane phosphotidylinositol transfer activity|phosphatidylinositol carrier activity|phosphatidylinositol transfer activity|phosphatidylinositol transporter activity|intermembrane phosphatidylinositol transfer activity Removes phosphatidylinositol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. GO:0008525 phosphatidylcholine transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008525 phosphatidylcholine transmembrane transporter activity Enables the directed movement of phosphatidylcholine into, out of or within a cell, or between cells. Phosphatidylcholine refers to a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. UBERON:0005946 outflow tract of atrium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005946 outflow part of atrium An outflow tract that is part of a cardiac atrium. GO:0008524 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008524 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008523 Reactome:R-HSA-199219|Reactome:R-HSA-429581|Reactome:R-HSA-199206 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: multivitamin(out) + Na+(out) = multivitamin(in) + Na+(in). Multivitamins include pantothenate, biotin and lipoate. GO:0008522 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008522 GO:0008521 acetyl-CoA transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008521 Reactome:R-HSA-727759|Reactome:R-HSA-5649742 acetyl-CoA transporter activity Enables the transfer of acetyl-CoA from one side of a membrane to the other. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis. GO:0008520 L-ascorbate:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008520 TC:2.A.40.6.1 sodium-dependent L-ascorbic acid transporter|sodium-dependent L-ascorbate transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: L-ascorbate(out) + Na+(out) = L-ascorbate(in) + Na+(in). CHEBI:83377 7(1)-hydroxychlorophyll a(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83377 CHEBI:58332 CDP-diacylglycerol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58332 CHEBI:58331 farnesyl triphosphate(3-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58331 CHEBI:83374 all-cis-polyprenyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83374 CHEBI:58330 1-alpha-D-galactosyl-sn-glycerol 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58330 CHEBI:83373 3-vinylbacteriochlorophyllide a(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83373 CHEBI:34368 stilbene-4,4'-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_34368 UBERON:0005956 outflow part of left ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005956 vestibulum aortae|left ventricular outflow tract|outflow tract of left ventricle|aortic vestibule|LVOT|Sibson vestibule|left ventricular outflow|heart left ventricle outflow tract Anterosuperior fibrous portion of the left ventricle that connects to the ascending aorta. CHEBI:58339 3'-phosphonato-5'-adenylyl sulfate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58339 UBERON:0005953 outflow part of right ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005953 right ventricle pulmonary outflow tract|pulmonary conus|pulmonary cone|arterial cone|conus arteriosus|conus arteriosus (infundibulum)|outflow tract of right ventricle|infundibulum of right ventricle|right ventricular outflow tract|RVOT|infundibulum|pulmonary conus Anteriosuperior, smooth-walled portion of the cavity of the right ventricle, beginning at the supraventricular crest and terminating in the pulmonary trunk CHEBI:58337 5,10-(methanylylidene)tetrahydromethanopterin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58337 CHEBI:58336 alpha-D-galactose 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58336 CHEBI:58335 sedoheptulose 1,7-bisphosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58335 CHEBI:58334 cyclohexyl isocyanide(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58334 CHEBI:58333 isoorientin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58333 GO:0008539 obsolete proteasome inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008539 proteasome inhibitor activity|PI-31 OBSOLETE. Stops, prevents or reduces the activity of the proteasome complex. The proteasome complex performs regulated ubiquitin-dependent cytosolic and nuclear proteolysis. GO:0008538 obsolete proteasome activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008538 proteasome activator activity|PA28 OBSOLETE. Catalysis of the activation of the proteasome, a large multisubunit complex which performs regulated ubiquitin-dependent cytosolic and nuclear proteolysis. GO:0008537 proteasome activator complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0008537 PA28 A multisubunit complex that activates the hydrolysis of small nonubiquitinated peptides by binding to the proteasome core complex. GO:0008536 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008536 GO:0008535 respiratory chain complex IV assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008535 cytochrome c oxidase complex assembly|cytochrome c oxidase biogenesis The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase), the terminal member of the respiratory chain of the mitochondrion and some aerobic bacteria. Cytochrome c oxidases are multi-subunit enzymes containing from 13 subunits in the mammalian mitochondrial form to 3-4 subunits in the bacterial forms. GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008534 Reactome:R-HSA-110229|MetaCyc:3.2.2.23-RXN|EC:3.2.2.23|Reactome:R-HSA-110243|Reactome:R-HSA-110244 8-oxoguanine DNA glycosylase activity|DNA glycohydrolase [2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimide releasing]|purine-specific oxidized base lesion DNA N-glycosylase activity|Fpg protein|2,6-diamino-4-hydroxy-5(N-methyl)formamidopyrimidine-DNA glycosylase activity|formamidopyrimidine-DNA glycosylase activity|DNA-formamidopyrimidine glycosylase activity|deoxyribonucleate glycosidase activity|bifunctional DNA glycosylase activity|2,6-diamino-4-hydroxy-5N-formamidopyrimidine-DNA glycosylase activity|Fapy-DNA glycosylase activity|DNA glycosylase/AP-lyase activity|DNA glycosylase/beta-lyase activity|oxidized purine base lesion DNA N-glycosylase activity Catalysis of the removal of oxidized purine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar. The reaction involves the formation of a covalent enzyme-substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apurinic (AP) site. GO:0008533 obsolete astacin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008533 astacin activity|astacus proteinase activity|Astacus proteinase activity|crayfish small-molecule proteinase activity OBSOLETE. Catalysis of the hydrolysis of peptide bonds in substrates containing five or more amino acids, preferentially with Ala in P1', and Pro in P2'. GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008532 RHEA:14389|EC:2.4.1.149|Reactome:R-HSA-2025724|MetaCyc:2.4.1.149-RXN uridine diphosphoacetylglucosamine-acetyllactosaminide beta1->3-acetylglucosaminyltransferase|uridine diphosphoacetylglucosamine-acetyllactosaminide beta-1,3-acetylglucosaminyltransferase|GnTE activity|N-acetyllactosamine beta(1,3)N-acetylglucosaminyltransferase activity|UDP-GlcNAc:GalR, beta-D-3-N-acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-1,4-N-acetyl-D-glucosamine beta-1,3-acetyl-D-glucosaminyltransferase activity|galbeta1->4GlcNAc-R beta1->3 N-acetylglucosaminyltransferase activity|poly-N-acetyllactosamine extension enzyme activity|UDP-GlcNAc:Galbeta-(1,4)-GlcNAcbeta-r-beta-(1,3)-N-acetylglucosaminyltransferase activity|UDP-GlcNAc:Galbeta-1,4-GlcNAcbeta-beta-1,3-N-acetylglucosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R. GO:0008531 riboflavin kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008531 Reactome:R-HSA-196964|MetaCyc:RIBOFLAVINKIN-RXN|KEGG_REACTION:R00549|EC:2.7.1.26|RHEA:14357 riboflavine kinase activity|riboflavin kinase (phosphorylating)|ATP:riboflavin 5'-phosphotransferase activity|FK|flavokinase activity Catalysis of the reaction: ATP + riboflavin = ADP + FMN + 2 H(+). GO:0008530 obsolete exogenous peptide receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008530 exogenous peptide receptor activity OBSOLETE. Combining with an extracellular peptide to initiate a change in cell activity. CHEBI:83389 furan-2,5-dicarboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83389 CHEBI:83388 5-(dihydroxymethyl)-2-furoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83388 CHEBI:58321 L-allysine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58321 CHEBI:83387 5-formyl-2-furoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83387 UBERON:2001632 ectopterygoid tooth biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_2001632 Tooth that is attached to the ectopterygoid bone. CHEBI:83386 2-(dihydroxymethyl)-5-formylfuran biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83386 CHEBI:58320 ammonioacetone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58320 CHEBI:83385 2,5-diformylfuran biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83385 CHEBI:83384 D-glucaro-1,5-lactone(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83384 CHEBI:83383 D-galactaro-1,5-lactone(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83383 CHEBI:58329 (+)-taxifolin(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58329 UBERON:0005945 neurocranial trabecula biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005945 trabecula|neurocranial trabeculae|trabecular cartilage UBERON:0005944 axial skeleton plus cranial skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005944 skeleton axiale Subdivision of skeleton which consists of cranial skeleton, set of all vertebrae, set of all ribs and sternum[FMA, modified]. CHEBI:58328 D-allose 6-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58328 CHEBI:58326 N(omega),N(omega)-dimethyl-L-argininium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58326 CHEBI:58325 1-ammonio-1-deoxy-scyllo-inositol 4-phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58325 CHEBI:58324 N(1)-acetylspermidinium(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58324 CHEBI:383703 3,6-diamino-10-methylacridinium chloride biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_383703 CHEBI:58323 hydrogenobyrinate(6-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58323 CHEBI:58322 3-mercapto-2-mercaptomethylpropanoate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58322 CHEBI:48995 5-hydroxyquinolin-2(1H)-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48995 GO:0008509 anion transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008509 Reactome:R-HSA-166214 anion transporter activity Enables the transfer of a negatively charged ion from one side of a membrane to the other. GO:0008508 bile acid:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008508 Reactome:R-HSA-194121|Reactome:R-HSA-433089|Reactome:R-HSA-194187 sodium/bile acid symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: bile acid(out) + Na+(out) = bile acid(in) + Na+(in). CHEBI:48994 quinolin-6-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48994 GO:0008507 sodium:iodide symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008507 Reactome:R-HSA-5658195|Reactome:R-HSA-429591 sodium/iodide symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: iodide(out) + Na+(out) = iodide(in) + Na+(in). UBERON:0005928 external naris biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005928 blowhole|nostril|anterior nares|naris|anterior naris|external nares A naris that provides one of the small external openings of the head that give passage to air for breathing. CHEBI:48996 6-hydroxyquinolin-2(1H)-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48996 GO:0008506 sucrose:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008506 sucrose:hydrogen symporter activity|hydrogen/sucrose transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sucrose(out) + H+(out) = sucrose(in) + H+(in). GO:0008505 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008505 CHEBI:48999 4-hydroxyphenylacetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48999 GO:0008504 monoamine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008504 Reactome:R-HSA-380620|Reactome:R-HSA-379393|Reactome:R-HSA-444160|Reactome:R-HSA-5660706|Reactome:R-HSA-380586|Reactome:R-HSA-372542 Enables the transfer of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), from one side of a membrane to the other. GO:0008503 benzodiazepine receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008503 Combining with benzodiazepines, a class of drugs with hypnotic, anxiolytic, anticonvulsive, amnestic and myorelaxant properties, to initiate a change in cell activity. GO:0008502 melatonin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008502 Combining with melatonin, N-acetyl-5-methoxytryptamine, to initiate a change in cell activity. Melatonin is a neuroendocrine substance that stimulates the aggregation of melanosomes in melanophores, thus lightening the skin. CHEBI:58319 coenzyme M(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58319 GO:0008501 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008501 GO:0008500 obsolete glycine-, glutamate-, thienylcyclohexylpiperidine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008500 glycine-, glutamate-, thienylcyclohexylpiperidine binding OBSOLETE. (Was not defined before being made obsolete). CHEBI:48991 7-methylxanthine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48991 CHEBI:48990 8-chloroquinolin-2(1H)-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48990 CHEBI:48993 quinolin-5-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48993 CHEBI:83399 marine xenobiotic metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83399 CHEBI:58310 N(2)-phenylacetyl-L-glutaminate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58310 CHEBI:34342 3-methylcholanthrene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_34342 CHEBI:83397 L-citrulline residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83397 CHEBI:83390 pentachlorobenzenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83390 CHEBI:58318 N-carbamoylputrescinium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58318 CHEBI:58315 L-tyrosine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58315 CHEBI:58314 (2R)-2-hydroxy monocarboxylic acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58314 CHEBI:58313 L-rhamnulose 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58313 CHEBI:58312 6-phosphonato-beta-D-glucosyl-(1->4)-D-glucose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58312 CHEBI:58311 (2R)-CDP-glycerol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58311 CHEBI:48984 8-methylquinoline biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48984 GO:0008519 ammonium transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008519 RHEA:28747|Reactome:R-HSA-446278|Reactome:R-HSA-444393|Reactome:R-HSA-444419|Reactome:R-HSA-5623051|Reactome:R-HSA-444416|Reactome:R-HSA-446277 ammonia transmembrane transporter activity Enables the transfer of ammonium from one side of a membrane to the other. Ammonium is the cation NH4+ which is formed from N2 by root-nodule bacteria in leguminous plants and is an excretory product in ammonotelic animals. CHEBI:48983 4-methylquinoline biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48983 GO:0008518 folate:anion antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008518 TC:2.A.48 reduced folate transmembrane transporter activity|reduced folate transporter|reduced folate carrier activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Folate derivative (out) + anion (in) = folate derivative (in) + anion (out). The Reduced Folate Carrier (RCF(SLC19A1) acts by an antiport mechanism. RCF carries several folate derivatives: MTX, PMX, ratitrexed, pralatrexate, 5-methyl THF, and 5-formyl THF. CHEBI:48986 4-methylquinolin-2(1H)-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48986 CHEBI:48985 8-chloroquinoline biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48985 GO:0008517 folic acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008517 Reactome:R-HSA-200729|Reactome:R-HSA-200652|Reactome:R-HSA-200720|Reactome:R-HSA-200680|Reactome:R-HSA-200646 folate transmembrane transporter activity|folate transporter activity|vitamin M transporter activity|vitamin B9 transporter activity|folic acid transporter activity Enables the transfer of folic acid (pteroylglutamic acid) from one side of a membrane to the other. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines. CHEBI:48988 8-hydroxyquinolin-2(1H)-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48988 GO:0008516 hexose uniporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008516 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexose(out) = hexose(in). GO:0008515 sucrose transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008515 sucrose permease (PTS) activity|sucrose permease activity Enables the transfer of sucrose from one side of a membrane to the other. Sucrose is the disaccharide O-beta-D-fructofuranosyl-(2->1)-alpha-D-glucopyranoside, a sweet-tasting, non-reducing sugar isolated industrially from sugar beet or sugar cane. CHEBI:48987 7-hydroxyquinolin-2(1H)-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48987 GO:0008514 organic anion transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008514 Reactome:R-HSA-2142859 Enables the transfer of organic anions from one side of a membrane to the other. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage. CHEBI:58309 UDP-N-acetylmuramate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58309 GO:0008513 secondary active organic cation transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008513 Reactome:R-HSA-549241 organic cation porter activity|polyspecific organic cation transmembrane transporter activity Enables the transfer of organic cations from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction. CHEBI:48989 8-methylquinolin-2(1H)-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48989 UBERON:0005913 zone of bone organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005913 bone organ zone CHEBI:58308 5-amino-4-chloro-2-(2-oxidomuconoyl)pyridazin-3(2H)-one(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58308 GO:0008512 sulfate:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008512 sulfate/hydrogen symporter activity|sulfate:hydrogen symporter activity|sulphate:hydrogen symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + H+(out) = sulfate(in) + H+(in). GO:0008511 sodium:potassium:chloride symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008511 Reactome:R-HSA-5623588|Reactome:R-HSA-426086 sodium/potassium/chloride symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + K+(out) + Cl-(out) = Na+(in) + K+(in) + Cl-(in). GO:0008510 sodium:bicarbonate symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008510 Reactome:R-HSA-425483|Reactome:R-HSA-5656219|Reactome:R-HSA-8878664 sodium:bicarbonate cotransporter activity|sodium/bicarbonate cotransporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + HCO3-(out) = Na+(in) + HCO3-(in). CHEBI:48980 quinolin-7-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48980 CHEBI:48982 methylquinoline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48982 CHEBI:48981 quinolin-8-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48981 CHEBI:58307 FADH2(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58307 CHEBI:58306 rifamycin B(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58306 CHEBI:58305 quercetin 3,3'-bissulfate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58305 CHEBI:58304 2-oxo-2H-pyran-4,6-dicarboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58304 CHEBI:58303 1-palmitoylglycerone 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58303 CHEBI:58302 UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58302 PR:000019255 cholecystokinin proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000019255 CCK/ClvPrd A cholecystokinin that has been processed by proteolytic cleavage. CHEBI:58301 taurolithocholic acid sulfate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58301 CHEBI:73931 GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73931 CHEBI:73933 dTDP-alpha-D-fucose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73933 CHEBI:73932 GDP-beta-L-colitose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73932 CHEBI:73935 2-chloroacrylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73935 CHEBI:73934 (S)-2-chloropropanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73934 CHEBI:73937 (3S)-3-hydroxy-L-enduracididine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73937 CHEBI:73936 L-enduracididine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73936 CHEBI:73939 (3S,5S)-carbapenam-3-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73939 CHEBI:73938 (3S)-3-hydroxy-L-arginine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73938 PR:000010818 myogenic factor 5 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000010818 Myf-5|MYF5|bHLHc2|class C basic helix-loop-helix protein 2 A protein that is a translation product of the human MYF5 gene or a 1:1 ortholog thereof. CHEBI:73940 GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73940 CHEBI:73943 (5R)-carbapenem-3-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73943 CHEBI:73946 GDP-beta-L-colitose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73946 GO:0033592 RNA strand annealing activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033592 Facilitates the base-pairing of complementary single-stranded RNA. GO:0033591 response to L-ascorbic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033591 response to ascorbic acid|response to L-ascorbate|response to vitamin C Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-ascorbic acid (vitamin C) stimulus. GO:0033590 response to cobalamin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033590 response to vitamin B12 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalamin (vitamin B12) stimulus. GO:0033599 regulation of mammary gland epithelial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033599 Any process that modulates the frequency, rate or extent of mammary gland epithelial cell proliferation. GO:0033598 mammary gland epithelial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033598 The multiplication or reproduction of mammary gland epithelial cells, resulting in the expansion of a cell population. Mammary gland epithelial cells make up the covering of surfaces of the mammary gland. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. GO:0033597 mitotic checkpoint complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033597 MCC A multiprotein complex that functions as a mitotic checkpoint inhibitor of the anaphase-promoting complex/cyclosome (APC/C). In budding yeast this complex consists of Mad2p, Mad3p, Bub3p and Cdc20p, and in mammalian cells it consists of MAD2, BUBR1, BUB3, and CDC20. GO:0033596 TSC1-TSC2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033596 tuberous sclerosis complex|tuberin-hamartin complex A protein complex consisting of at least tumerin and hamartin; its formation may regulate hamartin homomultimer formation. The complex acts as a GTPase activating protein (GAP) for the small GTPase (Rheb), and inhibits the TOR signaling pathway. GO:0033595 response to genistein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033595 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a genistein stimulus. GO:0033594 response to hydroxyisoflavone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033594 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyisoflavone stimulus. GO:0033593 BRCA2-MAGE-D1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033593 A heterodimeric protein complex formed of BRCA2 and MAGE-D1; may mediate the synergistic activities of the two proteins in regulating cell growth. CHEBI:73950 dTDP-alpha-D-fucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73950 CHEBI:73953 novobiocic acid(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73953 CHEBI:73955 descarbamoylnovobiocin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73955 CHEBI:73954 8-desmethylnovobiocic acid(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73954 CHEBI:73957 desmethyldescarbamoylnovobiocin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73957 CHEBI:73956 (S)-2-chloropropanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73956 GO:0033581 protein galactosylation in Golgi biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033581 protein amino acid galactosylation in Golgi The addition of a galactose unit to a protein amino acid in any compartment of the Golgi apparatus. GO:0033580 protein galactosylation at cell surface biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033580 protein amino acid galactosylation at cell surface The addition of a galactose unit to a protein amino acid at the surface of a cell. GO:0033589 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0033589 GO:0033588 elongator holoenzyme complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033588 Elongator core complex|Elongator holoenzyme complex A heterohexameric protein complex that is involved in modification of wobble nucleosides in tRNA. The complex can associate physically with hyperphosphorylated RNA polymerase II; it contains two discrete heterotrimeric subcomplexes. GO:0033587 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0033587 GO:0033586 L-phenylalanine biosynthetic process from chorismate via L-arogenate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033586 MetaCyc:PWY-3462 L-phenylalanine biosynthesis from chorismate via L-arogenate|L-phenylalanine anabolism from chorismate via L-arogenate|L-phenylalanine synthesis from chorismate via L-arogenate|L-phenylalanine formation from chorismate via L-arogenate The chemical reactions and pathways resulting in the formation of L-phenylalanine from other compounds, including chorismate, via the intermediate L-arogenate. GO:0033585 L-phenylalanine biosynthetic process from chorismate via phenylpyruvate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033585 MetaCyc:PHESYN L-phenylalanine anabolism from chorismate via phenylpyruvate|L-phenylalanine biosynthesis from chorismate via phenylpyruvate|L-phenylalanine formation from chorismate via phenylpyruvate|L-phenylalanine synthesis from chorismate via phenylpyruvate The chemical reactions and pathways resulting in the formation of L-phenylalanine from other compounds, including chorismate, via the intermediate phenylpyruvate. GO:0033584 tyrosine biosynthetic process from chorismate via L-arogenate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033584 MetaCyc:PWY-3461 tyrosine anabolism from chorismate via L-arogenate|tyrosine synthesis from chorismate via L-arogenate|tyrosine formation from chorismate via L-arogenate The chemical reactions and pathways resulting in the formation of tyrosine from other compounds, including chorismate, via the intermediate L-arogenate. GO:0033583 rhabdomere membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033583 The portion of the plasma membrane surrounding the rhabdomere. GO:0033582 protein galactosylation in cytosol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033582 protein amino acid galactosylation in cytosol The addition of a galactose unit to a protein amino acid in the cytosol. CHEBI:73962 (5S)-5-(carboxymethyl)-L-proline(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73962 CHEBI:73963 2-chloroacrylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73963 CHEBI:73966 nitric oxide synthase activator biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73966 GO:0033579 protein galactosylation in endoplasmic reticulum biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033579 protein amino acid galactosylation in endoplasmic reticulum|protein amino acid galactosylation in ER The addition of a galactose unit to a protein amino acid in the endoplasmic reticulum. CHEBI:73969 L-enduracididine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73969 GO:0033570 obsolete transferrin transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033570 OBSOLETE. Enables the transfer of transferrin from one side of a membrane to the other. GO:0033578 protein glycosylation in Golgi biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033578 terminal glycosylation|protein amino acid glycosylation in Golgi The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus. GO:0033577 protein glycosylation in endoplasmic reticulum biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033577 core glycosylation|protein amino acid glycosylation in endoplasmic reticulum|protein amino acid glycosylation in ER The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in the endoplasmic reticulum. GO:0033576 protein glycosylation in cytosol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033576 protein amino acid glycosylation in cytosol The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in the cytosol. GO:0033575 protein glycosylation at cell surface biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033575 protein amino acid glycosylation at cell surface The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid at the surface of a cell. GO:0033574 response to testosterone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033574 response to testosterone stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus. GO:0033573 high-affinity iron permease complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033573 IntAct:EBI-12592666 high affinity iron permease complex A protein complex composed of a multicopper ferroxidase that oxidizes Fe(II) to Fe(III), and a ferric iron permease that transports the produced Fe(III) into the cell. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. GO:0033572 transferrin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033572 melanotransferrin transport The directed movement of transferrin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0033571 lactoferrin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033571 The directed movement of lactoferrin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:73973 beta-D-Gal-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73973 CHEBI:73972 (3S)-3-hydroxy-L-arginine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73972 CHEBI:73975 3-oxo-octacosanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73975 CHEBI:73977 3-oxotetracosanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73977 CHEBI:73976 3-oxo-octacosanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73976 GO:0033569 lactoferrin transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033569 Enables the transfer of lactoferrin from one side of a membrane to the other. GO:0033568 lactoferrin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033568 Combining with lactoferrin and delivering lactoferrin into the cell via endocytosis. Lactoferrin is an iron-binding glycoprotein which binds ferric iron most efficiently at low pH. CHEBI:73978 (3S,5S)-carbapenam-3-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73978 PR:000010855 myosin-Ia biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000010855 MIHC|MYO1A|brush border myosin I|MYHL|BBM-I|myosin I heavy chain|BBMI A protein that is a translation product of the human MYO1A gene or a 1:1 ortholog thereof. GO:0033567 DNA replication, Okazaki fragment processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033567 The DNA metabolic process, occurring during lagging strand synthesis, by which RNA primers are removed from Okazaki fragments, the resulting gaps filled by DNA polymerization, and the ends ligated to form a continuous strand. GO:0033566 gamma-tubulin complex localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033566 gamma-tubulin complex localisation|establishment and maintenance of gamma-tubulin complex localization Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location. GO:0033565 ESCRT-0 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033565 Vps27p-Hse1p complex|Hrs/STAM complex A protein complex required for the recycling of Golgi proteins, formation of lumenal membranes and sorting of ubiquitinated proteins into those membranes. This complex includes Vps1p and Hse1p in yeast and the Hrs and STAM proteins in mammals. GO:0033564 anterior/posterior axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033564 anterior/posterior axon pathfinding|anterior-posterior axon guidance The process in which the migration of an axon growth cone is directed to a specific target site along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism. GO:0033563 dorsal/ventral axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033563 dorsal-ventral axon guidance|dorsal/ventral axon pathfinding|dorsoventral axon guidance The process in which the migration of an axon growth cone is directed to a specific target site along the dorsal-ventral body axis in response to a combination of attractive and repulsive cues. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism. GO:0033562 co-transcriptional gene silencing by RNA interference machinery biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033562 RNAi-mediated CTGS|cotranscriptional gene silencing by RNA interference machinery|co-transcriptional gene silencing by small RNA|small RNA-mediated cotranscriptional gene silencing|cotranscriptional gene silencing by small RNA A process in which the RNAi machinery mediates the degradation of nascent transcripts in association with chromatin. CHEBI:73971 (3S)-3-hydroxy-L-enduracididine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73971 GO:0033561 regulation of water loss via skin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033561 skin barrier function A process that modulates the rate or extent of water loss from an organism via the skin. GO:0033560 folate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033560 RHEA:31103|Reactome:R-HSA-197963|Reactome:R-HSA-197972 Catalysis of the reaction: 7,8-dihydrofolate + NADP+ = folate + NADPH + H+. CHEBI:73984 beta-D-Gal-(1->4)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73984 CHEBI:73986 beta-D-Glc-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73986 CHEBI:73988 beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73988 GO:0033559 unsaturated fatty acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033559 MetaCyc:PWY-762|MetaCyc:PWY-782 unsaturated fatty acid metabolism The chemical reactions and pathways involving an unsaturated fatty acid, any fatty acid containing one or more double bonds between carbon atoms. CHEBI:73987 alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73987 GO:0033558 protein deacetylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033558 Reactome:R-HSA-8952069|Reactome:R-HSA-9626962|Reactome:R-HSA-5693092 Catalysis of the hydrolysis of an acetyl group or groups from a protein substrate. CHEBI:83308 dioleoylphosphatidate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83308 GO:0033557 Slx1-Slx4 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033557 A heterodimeric protein complex that possesses an endonuclease activity that specifically cleaves certain types of branched DNA structures; because such structures often form during the replication ribosomal DNA (rDNA) repeats, the complex plays a role in the maintenance of rDNA. The subunits are known as Slx1 and Slx 4 in budding and fission yeasts, and are conserved in eukaryotes. GO:0033556 dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033556 dolichyl-P-Glc:Man7GlcNAc2-PP-dolichyl glucosyltransferase activity Catalysis of the addition of a glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Man(7)GlcNAc(2)-PP-Dol. GO:0033555 multicellular organismal response to stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033555 Any process that results in a change in state or activity of a multicellular organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). GO:0033554 cellular response to stress biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0033554 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). GO:0033553 rDNA heterochromatin biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033553 ribosomal DNA heterochromatin|nuclear rDNA heterochromatin|ribosomal DNA heterochromatin of cell nucleus|ribosomal DNA heterochromatin of nucleus A region of heterochromatin located at the rDNA repeats in a chromosome. GO:0033552 response to vitamin B3 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033552 response to nicotinamide|response to niacin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B3 stimulus. CHEBI:73980 3-oxohexacosanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73980 GO:0033551 monopolin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033551 monopolin subcomplex Csm1/Lrs4|Pcs1/Mde4 complex A protein complex required for clamping microtubule binding sites, ensuring orientation of sister kinetochores to the same pole (mono-orientation) during meiosis I. In the yeast S. cerevisiae this complex consists of Csm1p, Lrs4p, Hrr25p and Mam1p; in S. pombe Psc1 and Mde4 have been identified as subunits. GO:0033550 MAP kinase tyrosine phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033550 tyrosine-specific MAP kinase phosphatase activity Catalysis of the reaction: MAP kinase tyrosine phosphate + H2O = MAP kinase tyrosine + phosphate. CHEBI:73995 2-[(3S)-3-amino-3-carboxypropyl]-L-histidine zwitterion residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73995 CHEBI:73997 GDP-N-acetyl-alpha-D-perosamine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73997 CHEBI:73996 GDP-4-amino-4,6-dideoxy-alpha-D-mannose(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73996 GO:0033549 MAP kinase phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033549 MAPK phosphatase activity Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate. CHEBI:73999 1-hexadecanoyl-2-[(9Z)-hexadec-9-enoyl]-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73999 GO:0033548 myo-inositol hexakisphosphate biosynthetic process, lipid-independent biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033548 MetaCyc:PWY-4661 myo-inositol hexakisphosphate synthesis, lipid-independent|myo-inositol hexakisphosphate anabolism, lipid-independent|phytate biosynthesis, lipid-independent|phytate biosynthetic process, lipid-independent|myo-inositol hexakisphosphate biosynthesis, lipid-independent|myo-inositol hexakisphosphate formation, lipid-independent The chemical reactions and pathways resulting in the formation of phytic acid, myo-inositol hexakisphosphate, by the successively phosphorylation of myo-inositol or an inositol trisphosphate; the inositol trisphosphates that may be used by this pathway are inositol 3,4,5-trisphosphate and inositol 3,4,6trisphosphate. CHEBI:73998 1-hexadecanoyl-2-[(9Z)-hexadec-9-enoyl]-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73998 GO:0033547 obsolete myo-inositol hexakisphosphate biosynthetic process, via direct phosphorylation of inositol 1,4,5-trisphosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033547 MetaCyc:PWY-4541 myo-inositol hexakisphosphate biosynthesis, via direct phosphorylation of inositol 1,4,5-trisphosphate|myo-inositol hexakisphosphate biosynthetic process, via direct phosphorylation of inositol 1,4,5-trisphosphate|phytate biosynthesis, via direct phosphorylation of inositol 1,4,5-trisphosphate|phytate biosynthetic process, via direct phosphorylation of inositol 1,4,5-trisphosphate|myo-inositol hexakisphosphate anabolism, via direct phosphorylation of inositol 1,4,5-trisphosphate|myo-inositol hexakisphosphate synthesis, via direct phosphorylation of inositol 1,4,5-trisphosphate|myo-inositol hexakisphosphate formation, via direct phosphorylation of inositol 1,4,5-trisphosphate OBSOLETE. The chemical reactions and pathways resulting in the formation of 1D myo-inositol 1,2,3,4,5,6-hexakisphosphate, phytate, by a pathway using inositol 1,4,5-trisphosphate produced from phosphatidylinositol 4,5-biphosphate hydrolysis by phospholipase C; in this pathway, inositol 1,4,5-trisphosphate is successively phosphorylated to yield inositol hexakisphosphate. GO:0033546 myo-inositol hexakisphosphate biosynthetic process, via inositol 1,3,4-trisphosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033546 MetaCyc:PWY-6554 myo-inositol hexakisphosphate biosynthesis, via inositol 1,3,4-trisphosphate|phytate biosynthetic process, via inositol 1,3,4-trisphosphate|phytate biosynthesis, via inositol 1,3,4-trisphosphate|myo-inositol hexakisphosphate anabolism, via inositol 1,3,4-trisphosphate|myo-inositol hexakisphosphate synthesis, via inositol 1,3,4-trisphosphate|myo-inositol hexakisphosphate formation, via inositol 1,3,4-trisphosphate The chemical reactions and pathways resulting in the formation of 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate, phytate, by a pathway using inositol 1,4,5-trisphosphate produced from phosphatidylinositol 4,5-biphosphate hydrolysis by phospholipase C; in this pathway, inositol 1,4,5-trisphosphate is first converted to inositol 1,3,4-trisphosphate, and then phosphorylated further. GO:0008589 regulation of smoothened signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008589 regulation of smoothened by patched|regulation of hh signaling pathway|regulation of hedgehog signaling pathway|regulation of smoothened activity|regulation of smoothened signalling pathway|regulation of smoothened receptor activity by patched Any process that modulates the frequency, rate or extent of smoothened signaling. GO:0008588 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008588 CHEBI:83317 sterol biosynthesis inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83317 GO:0008587 imaginal disc-derived wing margin morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008587 wing margin morphogenesis The process in which the anatomical structures of the imaginal disc-derived wing margin are generated and organized. The wing margin is a strip of cells in the third instar disc at the boundary between the presumptive dorsal and ventral surfaces of the wing blade. GO:0008586 imaginal disc-derived wing vein morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008586 wing vein morphogenesis The process in which anatomical structures of the veins on an imaginal disc-derived wing are generated and organized. GO:0008585 female gonad development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008585 ovary development|ovarian development The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure. GO:0008584 male gonad development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008584 testis development|testicular development The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure. GO:0008583 mystery cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008583 The process in which an undifferentiated cell acquires the features of a mystery cell. The mystery cells are a precluster of cells that emerge from the compound eye morphogenetic furrow, normally positioned between R3 and R4. They then disappear into the surrounding pool of undifferentiated cells and have no known fate in the mature ommatidium. An example of this process is found in Drosophila melanogaster. GO:0008582 regulation of synaptic growth at neuromuscular junction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008582 Any process that modulates the frequency, rate or extent of synaptic growth at neuromuscular junctions. GO:0008592 regulation of Toll signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008592 regulation of Tl signalling pathway|regulation of Toll signalling pathway|regulation of Tl signaling pathway Any process that modulates the frequency, rate or extent of the Tl signaling pathway. CHEBI:58398 (2S)-2-hydroxyphytanate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58398 GO:0008591 regulation of Wnt signaling pathway, calcium modulating pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008591 regulation of Wnt receptor signaling pathway, calcium modulating pathway|regulation of Wnt-activated signaling pathway, calcium modulating pathway|regulation of frizzled-2 signaling pathway|regulation of frizzled-2 signalling pathway Any process that modulates the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC). GO:0008590 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008590 CHEBI:58396 aerobactinate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58396 CHEBI:58395 myricetin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58395 CHEBI:58394 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58394 CHEBI:58393 aureusidin-6-olate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58393 CHEBI:58392 alpha-D-glucose 1,6-bisphosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58392 CHEBI:58391 all-trans-nonaprenyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58391 GO:0033545 myo-inositol hexakisphosphate biosynthetic process, lipid-dependent biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033545 MetaCyc:PWY-6555 phytate biosynthesis, lipid-dependent|phytate biosynthetic process, lipid-dependent|myo-inositol hexakisphosphate biosynthesis, lipid-dependent|myo-inositol hexakisphosphate formation, lipid-dependent|myo-inositol hexakisphosphate synthesis, lipid-dependent|myo-inositol hexakisphosphate anabolism, lipid-dependent The chemical reactions and pathways resulting in the formation of 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate, phytate, by a pathway using inositol 1,4,5-trisphosphate produced from phosphatidylinositol 4,5-biphosphate hydrolysis by phospholipase C. GO:0033544 fatty acid beta-oxidation, unsaturated, even number, epimerase pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033544 A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. In this pathway, the intermediate 2,4-dienoyl-CoA is converted to cis-2-enoyl-CoA through one more cycle of the core beta-oxidation pathway. Cis-2-enoyl-CoA cannot be completely degraded via the core beta-oxidation pathway because hydratation of cis-2-enoyl-CoA yields D-3-hydroxyacyl-CoA, which is not a substrate for 3-hydroxylacyl-CoA dehydrogenase. Cis-2-enoyl-CoA must enter the so-called epimerase pathway, which involves converting D-3-hydroxyacyl-CoA to L-3-hydroxyacyl-CoA by 3-hydroxylacyl-CoA epimerase or by two stereo-specific enoyl-CoA hydratases. L-3-hydroxyacyl-CoA then returns to the core beta-oxidation pathway. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively). GO:0033543 fatty acid beta-oxidation, unsaturated, even number, reductase/isomerase pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033543 A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. In this pathway, the intermediate 2,4-dienoyl-CoA is converted to trans-2-enoyl-CoA by 2,4-dienoyl-CoA reductase and delta3-delta2-enoyl-CoA isomerase; trans-2-enoyl-CoA returns to the core beta-oxidation pathway for further degradation. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively). GO:0033542 fatty acid beta-oxidation, unsaturated, even number biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033542 MetaCyc:PWY-5138 A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively). CHEBI:73991 alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73991 GO:0033541 fatty acid beta-oxidation, unsaturated, odd number biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033541 MetaCyc:PWY-5137 A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on odd-numbered carbons are degraded. In this pathway, a cis-3-enoyl-CoA is generated by the core beta-oxidation pathway, and then converted to a trans-2-enoyl-CoA, which can return to the core beta-oxidation pathway for complete degradation. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively). CHEBI:73990 2-oleoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73990 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033540 MetaCyc:PWY-5136 A fatty acid beta-oxidation pathway in which the initial step, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA oxidase; the electrons removed by oxidation pass directly to oxygen and produce hydrogen peroxide, which is cleaved by peroxisomal catalases. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively). CHEBI:73993 alpha-D-Gal-(1->3)-[alpha-L-Fuc-(1->2)]-beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73993 CHEBI:58399 isopenicillin N(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58399 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033539 MetaCyc:FAO-PWY A fatty acid beta-oxidation pathway in which the initial step of each oxidation cycle, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA dehydrogenase; the electrons removed by oxidation pass through the respiratory chain to oxygen and leave H2O as the product. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively). GO:0033538 ajugose biosynthetic process using galactan:galactan galactosyltransferase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033538 MetaCyc:PWY-5343 ajugose anabolism using galactan:galactan galactosyltransferase|ajugose synthesis using galactan:galactan galactosyltransferase|ajugose formation using galactan:galactan galactosyltransferase|ajugose biosynthesis using galactan:galactan galactosyltransferase The chemical reactions and pathways resulting in the formation of ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside, by a pathway in which galactan:galactan galactosyltransferase catalyzes chain elongation by transferring the alpha-galactosyl residue of one raffinose-family oligosaccharide to another. CHEBI:128459 valienol 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_128459 GO:0033537 ajugose biosynthetic process using galactinol:raffinose galactosyltransferase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033537 MetaCyc:PWY-5342 ajugose formation using galactinol:raffinose galactosyltransferase|ajugose synthesis using galactinol:raffinose galactosyltransferase|ajugose anabolism using galactinol:raffinose galactosyltransferase|ajugose biosynthesis using galactinol:raffinose galactosyltransferase The chemical reactions and pathways resulting in the formation of ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside, by a pathway in which galactinol:raffinose galactosyltransferase catalyzes chain elongation by transferring the alpha-galactosyl residue of galactinol to the oligosaccharide. GO:0033536 ajugose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033536 ajugose biosynthesis|ajugose anabolism|ajugose synthesis|ajugose formation The chemical reactions and pathways resulting in the formation of ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside. GO:0033535 ajugose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033535 ajugose metabolism The chemical reactions and pathways involving ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside. CHEBI:58390 N(6')-acetylkanamycin B(4+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58390 GO:0008599 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008599 GO:0008598 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008598 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008597 Reactome:R-HSA-139906 calcium-dependent protein serine/threonine phosphatase, intrinsic regulator activity Modulation of the activity of the enzyme calcium-dependent protein serine/threonine phosphatase. GO:0008596 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008596 GO:0008595 anterior/posterior axis specification, embryo biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008595 anterior/posterior axis determination, embryo The specification of the anterior/posterior axis of the embryo by the products of genes expressed maternally and genes expressed in the zygote. CHEBI:83324 pent-2-enoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83324 GO:0008594 photoreceptor cell morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008594 photoreceptor development The process in which the structures of a photoreceptor cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a photoreceptor cell, a sensory cell that reacts to the presence of light. An example of this is found in Drosophila melanogaster. GO:0008593 regulation of Notch signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008593 regulation of N signaling pathway|regulation of N signalling pathway|regulation of Notch signalling pathway Any process that modulates the frequency, rate or extent of the Notch signaling pathway. CHEBI:58387 3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58387 CHEBI:58386 (S)-2-hydroxyoctadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58386 CHEBI:58385 luteolin 7-O-beta-D-glucosiduronate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58385 CHEBI:58384 cadaverine(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58384 CHEBI:58383 phosphonoacetaldehyde(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58383 CHEBI:58382 5-ammoniopentanamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58382 CHEBI:58381 3-ADP-2-phosphoglycerate(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58381 CHEBI:58380 pseudouridine 5'-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58380 GO:0033534 verbascose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033534 verbascose anabolism|verbascose synthesis|verbascose formation|verbascose biosynthesis The chemical reactions and pathways resulting in the formation of verbascose, the pentasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside. GO:0033533 verbascose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033533 verbascose metabolism The chemical reactions and pathways involving verbascose, the pentasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside. GO:0033532 stachyose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033532 MetaCyc:PWY-5337 stachyose anabolism|stachyose synthesis|stachyose biosynthesis|stachyose formation The chemical reactions and pathways resulting in the formation of stachyose, the tetrasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside. GO:0033531 stachyose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033531 stachyose metabolism The chemical reactions and pathways involving stachyose, the tetrasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside. GO:0033530 raffinose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033530 raffinose metabolism The chemical reactions and pathways involving raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside. CHEBI:58389 trimethylammonium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58389 CHEBI:58388 heparan sulfate alpha-D-glucosaminide polyanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58388 CHEBI:24922 isoquinolines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24922 CHEBI:24921 isoquinoline alkaloid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24921 CHEBI:24923 isoquinolinol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24923 CHEBI:24928 isothiocyanic acid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_24928 CHEBI:24937 jasmonates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24937 CHEBI:24909 hydrocarbyladenosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24909 CHEBI:24911 isopiperitenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_24911 CHEBI:24913 isoprenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24913 CHEBI:2533 alachlor biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_2533 CHEBI:73913 antifolate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73913 CHEBI:2519 agroclavine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_2519 GO:0033493 esculetin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033493 MetaCyc:PWY-5349 esculetin biosynthesis|esculetin anabolism|esculetin synthesis|esculetin formation The chemical reactions and pathways resulting in the formation of esculetin, 6,7-dihydroxycoumarin. GO:0033492 esculetin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033492 esculetin metabolism The chemical reactions and pathways involving esculetin, 6,7-dihydroxycoumarin. GO:0033491 coniferin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033491 MetaCyc:PWY-116 coniferin metabolism The chemical reactions and pathways involving coniferin, 4-(3-hydroxyprop-1-en-1-yl)-2-methoxyphenyl beta-D-glucopyranoside. GO:0033490 cholesterol biosynthetic process via lathosterol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033490 MetaCyc:PWY66-341 cholesterol anabolism via lathosterol|cholesterol synthesis via lathosterol|cholesterol formation via lathosterol|cholesterol biosynthesis via lathosterol The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate lathosterol. GO:0033499 galactose catabolic process via UDP-galactose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033499 MetaCyc:PWY-3821 galactose catabolism via UDP-galactose|galactose degradation via UDP-galactose|galactose breakdown via UDP-galactose|Leloir Pathway The chemical reactions and pathways resulting in the breakdown of galactose, via the intermediate UDP-galactose. GO:0033498 galactose catabolic process via D-galactonate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033498 MetaCyc:GALDEG-PWY galactose catabolism via D-galactonate|galactose degradation via D-galactonate|galactose breakdown via D-galactonate The chemical reactions and pathways resulting in the breakdown of galactose, via the intermediate D-galactonate. GO:0033497 sinapate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033497 MetaCyc:PWY-5168 sinapate anabolism|sinapate biosynthesis|sinapate synthesis|sinapate formation The chemical reactions and pathways resulting in the formation of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate. GO:0033496 sinapate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033496 sinapate metabolism The chemical reactions and pathways involving sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate. GO:0033495 ferulate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033495 MetaCyc:PWY-5168 ferulate biosynthesis|ferulate anabolism|ferulate synthesis|ferulate formation The chemical reactions and pathways resulting in the formation of ferulate, (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate. GO:0033494 ferulate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033494 ferulate metabolism The chemical reactions and pathways involving ferulate, (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate. CHEBI:48975 substituted aniline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48975 CHEBI:10359 (-)-beta-chamigrene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_10359 UBERON:0005992 pulmonary valve cusp biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005992 pulmonary valvular cusp|semilunar valvule of pulmonary valve|pulmonary semilunar valvule|semilunar cusp of pulmonary valve|cusp of pulmonary valve The three fibrous triangular components and associated flap of the pulmonary valve UBERON:0005991 aortic valve anulus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005991 aortic valvar anulus|anulus of aortic valve|fibrous ring of aortic valve|aortic anulus The fibrous ring of the aortic valve that attaches the cusps of aortic valve to the wall of left ventricle, and which consists of portions of the fibrous scallops of the posterior, right anterior and left anterior cusps UBERON:0005990 aortic valve cusp biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005990 cusp of aortic valve|aortic semilunar valvule|semilunar valvule of aortic valve|aortic valvular cusp The three fibrous triangular components and associated flap of the aortic valve CHEBI:10352 beta-amyrin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_10352 CHEBI:10357 (-)-beta-caryophyllene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_10357 CHEBI:83290 N(alpha)-(L-gamma-glutamyl)-hercynyl-L-cysteine sulfoxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83290 UBERON:0005998 tricuspid valve cusp biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005998 septal leaflet of right-sided tricuspid valve|cuspis septalis valvae atrioventricularis dextrae|septal tricuspid leaflet|septal cusp of tricuspid valve|cuspis septalis (valva tricuspidalis)|septal cusp of right atrioventricular valve|septal leaflet of tricuspid valve The three fibrous triangular components and associated flaps of the tricuspid valve UBERON:0005997 tricuspid valve anulus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005997 tricuspid valvar anulus|tricuspid anulus|fibrous ring of tricuspid valve|anulus of tricuspid valve The fibrous ring of the tricuspid valve that attaches the cusps of tricuspid valve to the heart, and which consists of portions of the fibrous scallops of the anterior cusp (infundibular cusp), the posterior cusp (marginal cusp), and the septal cusp (medial cusp) UBERON:0005996 mitral valve cusp biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005996 The two fibrous components and associated flaps of the mitral valve CHEBI:2571 aliphatic alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_2571 UBERON:0005995 mitral valve anulus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005995 fibrous ring of mitral valve|mitral valvar anulus|anulus of mitral valve|mitral anulus|mitral annulus The fibrous ring of the mitral valve that attaches the cusps of mitral valve to the heart, and which consists of portions of the fibrous scallops of the anterior and posterior cusps UBERON:0005994 chorda tendineae biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005994 chordae tendineae cordis|chordae tendinea The tendinous strands that connect the papillary muscles on the wall of the ventricles to the leaflets of the atrioventricular valves; the chordae tendineae serve to prevent the AV valves from prolapsing back into the atria UBERON:0005993 pulmonary valve anulus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005993 fibrous ring of pulmonary valve|anulus of pulmonary valve|pulmonary anulus|pulmonary valvar anulus The fibrous ring of the pulmonary valve that attaches the cusps of pulmonary valve to the wall of right ventricle, and which consists of portions of the fibrous scallops of the anterior, right posterior and left posterior cusps CHEBI:48965 trans-chalcone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48965 CHEBI:48968 (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48968 UBERON:0005979 crista terminalis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005979 crista terminalis atrii dextri|crista terminalis of right atrium|crista terminalis cordis The vertical crest of the interior wall of the right atrium that lies to the right of the sinus of the vena cava and separates this from the remainder of the right atrium CHEBI:2588 Alkylated DNA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_2588 PR:000020180 haptoglobin proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000020180 HP/ClvPrd A haptoglobin that has been processed by proteolytic cleavage. UBERON:0005989 atrioventricular septum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005989 membranous atrioventricular septum The wall of the heart that separates the right atrium and left ventricle; and is located just above the septal cusp of the tricuspid valve UBERON:0005988 atrium myocardial trabecula biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005988 atrial trabecula|trabecular layer of atrium|atrium myocardial trabeculae|trabecula of atrium|trabecular layer of the atrium The supporting bundles of muscular fibers lining the walls of the atrial myocardium CHEBI:48969 (2R,3R)-2,3-dihydroxy-2,3-dihydrobenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48969 CHEBI:2580 unsaturated fatty acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_2580 OIO:hasNarrowSynonym has_narrow_synonym biolink:OntologyClass go-plus http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym UBERON:0005985 coronary vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005985 Any of the arteries or veins that supply blood to the heart or return blood from the heart muscles to the circulation UBERON:0005983 heart layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005983 The laminar structure of the heart CHEBI:48951 cyclohexenone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48951 CHEBI:48950 L-2,4-diaminobutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48950 CHEBI:24983 ketoxime biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_24983 CHEBI:48953 cyclohexenones biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48953 CHEBI:24982 ketotriose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24982 CHEBI:24981 ketotetrose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24981 CHEBI:48954 7,8-dihydroneopterin 3'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48954 UBERON:0005969 eye trabecular meshwork biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005969 scleral trabecular|cribiform ligament|eye trabecular meshwork|reticulum trabeculare|pectinate ligament|iridis|pectinate ligament of iris|ligamentum pectinatum|Hueck's ligament|trabecular mesh|ligamentum pectinatum iridis|scleral trabecule|trabecular meshwork of the eye|scleral trabeculae|scribiform ligament|ligamentum peactin-tum iridis|trabecular meshwork|ligamentum pectinatum anguli iridocornealis|reticulum trabeculare sclerae A pore-like structure surrounding the entire circumference of the anterior chamber of the eye through which aqueous humor circulates[MP]. CHEBI:48957 N(2)-succinyl-L-glutamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48957 CHEBI:48956 5-O-phosphono-D-ribofuranosyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48956 CHEBI:34306 20-HETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_34306 CHEBI:24980 ketotetrose phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24980 UBERON:0005970 brain commissure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005970 any of the nerve fiber tracts that span the longitudinal fissure between the cerebral and/or cerebellar hemispheres of the brain CHEBI:2559 aldohexose 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_2559 CHEBI:48959 monoazo compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48959 CHEBI:48958 1,1'-azobis(N,N-dimethylformamide) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48958 UBERON:0005971 amniotic fold biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005971 amnionic fold A sheet of somatopleure that grows upward over the embryo and eventually meets in the midline enclosing the embryo, eventually giving rise to the amnion and chorion[Kardong]. CHEBI:24995 lactam biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24995 CHEBI:48940 (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48940 CHEBI:48942 isovalerate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48942 CHEBI:48944 isobutyrate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48944 CHEBI:48943 isobutyraldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48943 CHEBI:48946 2-methylbutyrate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48946 CHEBI:24996 lactate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_24996 CHEBI:34317 3,3',4,4',5-pentachlorobiphenyl biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_34317 CHEBI:24990 kynurenamines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24990 CHEBI:34310 (24S)-24-hydroxycholesterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_34310 CHEBI:10365 (5S)-3-acetyl-4-hydroxy-5-{[4-(3-methylbut-2-en-1-yl)-1H-indol-3-yl]methyl}-1,5-dihydro-2H-pyrrol-2-one biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_10365 CHEBI:10363 beta-cubebene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_10363 CHEBI:34311 27-O-demethylrifamycin SV biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_34311 CHEBI:10362 beta-cryptoxanthin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_10362 CHEBI:48948 demethylsulochrin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48948 UBERON:0005966 outflow part of left atrium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005966 outflow tract of left atrium|main part of left atrium An outflow tract of atrium that is part of a left atrium. CHEBI:48947 clavulanic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48947 UBERON:0005965 outflow part of right atrium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0005965 main part of right atrium|outflow tract of right atrium Outflow part of atrium which consists of wall and cavity of the outflow part of right atrium and the tricuspid valve.[FMA] CHEBI:48949 3-phenylcyclohexa-3,5-diene-1,2-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48949 CHEBI:24962 ketoaldonic acid phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24962 CHEBI:24961 ketoaldonate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24961 CHEBI:24960 ketoaldehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24960 CHEBI:48931 (2S,3R)-3-carboxy-2,3-dihydroxypropanoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48931 CHEBI:48930 (2R,3S)-3-carboxy-2,3-dihydroxypropanoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48930 CHEBI:24966 keto-D-gluconate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24966 CHEBI:48932 L-glyceraldehyde 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48932 CHEBI:24965 deoxyketohexose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24965 CHEBI:24964 deoxyketohexose phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24964 CHEBI:24963 ketoaldonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24963 CHEBI:48937 phytane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48937 CHEBI:48939 (25R)-5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48939 CHEBI:24967 ketogluconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24967 CHEBI:24973 ketohexose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24973 CHEBI:24972 ketohexose phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24972 CHEBI:24971 ketohexose monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24971 CHEBI:24970 ketohexose bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24970 CHEBI:24977 ketopentose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24977 CHEBI:24976 ketopentose phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24976 CHEBI:24975 ketooctose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24975 CHEBI:48923 erythromycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48923 CHEBI:48926 S-(hydroxymethyl)glutathione biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48926 CHEBI:48928 6-phospho-D-gluconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48928 CHEBI:48927 N-acyl-L-alpha-amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48927 CHEBI:24978 ketose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24978 CHEBI:48929 3-carboxy-2,3-dihydroxypropanoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48929 CHEBI:24943 juvenile hormone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24943 CHEBI:2596 alliin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_2596 UBERON:0015329 respiratory system basement membrane biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015329 A basement membrane of epithelium that is part of a respiratory system. CHEBI:10334 alpha-terpinene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_10334 CHEBI:48914 glucaric acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48914 CHEBI:48916 altraric acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48916 CHEBI:24951 kanamycins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24951 CHEBI:48901 thiazoles biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48901 CHEBI:10329 alpha-ribazole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_10329 CHEBI:24957 keto-disaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24957 CHEBI:48905 (9Z,11E,13S,15Z)-13-hydroperoxyoctadeca-9,11,15-trienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48905 CHEBI:48907 (9Z,11E,15Z)-octadeca-9,11,15-trienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48907 CHEBI:73898 Gly-Gln biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73898 GO:0033649 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0033649 GO:0033648 host intracellular membrane-bounded organelle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033648 host intracellular membrane-enclosed organelle Organized structure of distinctive morphology and function, as found in host cells, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0033647 host intracellular organelle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033647 Organized structure of distinctive morphology and function, occurring within the host cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0033646 host intracellular part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0033646 host cell intracellular part Any constituent part of the living contents of a host cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0008689 3-demethylubiquinone-9 3-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008689 RHEA:17049|MetaCyc:DHHB-METHYLTRANSFER-RXN|EC:2.1.1.64 S-adenosyl-L-methionine:2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone-O-methyltransferase activity|5-demethylubiquinone-9 methyltransferase activity|S-adenosyl-L-methionine:2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone 3-O-methyltransferase activity|OMHMB-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinone-9 = S-adenosyl-L-homocysteine + ubiquinone-9. GO:0033645 host cell endomembrane system biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033645 A collection of membranous structures involved in transport within the host cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0008688 3-(3-hydroxyphenyl)propionate hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008688 EC:1.14.13.-|RHEA:24785|KEGG_REACTION:R06786|MetaCyc:MHPHYDROXY-RXN Catalysis of the reaction: 3-(3-hydroxyphenyl)propionate + NADH + oxygen + H+ = 3-(2,3-dihydroxyphenyl)propionate + NAD+ + H2O. GO:0008687 3,4-dihydroxyphenylacetate 2,3-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008687 EC:1.13.11.15|MetaCyc:1.13.11.15-RXN|KEGG_REACTION:R03303|UM-BBD_reactionID:r0364|RHEA:15633 3,4-dihydroxyphenylacetic acid 2,3-dioxygenase activity|HPC dioxygenase activity|homoprotocatechuate 2,3-dioxygenase activity|3,4-dihydroxyphenylacetate:oxygen 2,3-oxidoreductase (decyclizing) Catalysis of the reaction: 3,4-dihydroxyphenylacetate + O(2) = 5-formyl-2-hydroxyhepta-2,4-dienedioate + H(+). GO:0008686 3,4-dihydroxy-2-butanone-4-phosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008686 RHEA:18457|KEGG_REACTION:R07281|EC:4.1.99.12|MetaCyc:DIOHBUTANONEPSYN-RXN Catalysis of the reaction: D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H(+). GO:0008685 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008685 MetaCyc:RXN0-302|KEGG_REACTION:R05637|RHEA:23864|EC:4.6.1.12 MECDP-synthase activity|MECP synthase activity|2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol CMP-lyase (cyclizing)|2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol CMP-lyase (cyclizing; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate-forming) Catalysis of the reaction: 4-CDP-2-C-methyl-D-erythritol 2-phosphate = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + CMP. GO:0008684 2-oxopent-4-enoate hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008684 RHEA:22580|UM-BBD_enzymeID:e0078|MetaCyc:2-OXOPENT-4-ENOATE-HYDRATASE-RXN|EC:4.2.1.80 OEH activity|4-hydroxy-2-oxopentanoate hydro-lyase (2-oxopent-4-enoate-forming)|2-keto-4-pentenoate hydratase activity|2-keto-4-pentenoate (vinylpyruvate)hydratase activity|4-hydroxy-2-oxopentanoate hydro-lyase activity Catalysis of the reaction: 4-hydroxy-2-oxopentanoate = 2-oxopent-4-enoate + H2O. GO:0008683 2-oxoglutarate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008683 MetaCyc:RXN-7774|RHEA:10524|EC:4.1.1.71|KEGG_REACTION:R00272 2-oxoglutarate carboxy-lyase activity|2-oxoglutarate carboxy-lyase (succinate-semialdehyde-forming)|alpha-ketoglutaric decarboxylase activity|alpha-ketoglutarate decarboxylase activity|pre-2-oxoglutarate decarboxylase activity Catalysis of the reaction: 2-oxoglutarate + H(+) = CO(2) + succinate semialdehyde. GO:0008682 2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008682 RHEA:50908|EC:1.14.99.60|MetaCyc:OCTAPRENYL-METHYL-METHOXY-BENZOQ-OH-RXN demethoxyubiquinone monooxygenase|demethoxy-ubiquinone hydroxylase Catalysis of the reaction: 2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone + O2 = 2-octoprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone. GO:0008681 2-octaprenyl-6-methoxyphenol hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008681 EC:1.14.14.-|RHEA:29407|MetaCyc:2-OCTAPRENYL-6-METHOXYPHENOL-HYDROX-RXN Catalysis of the reaction: 2-octaprenyl-6-methoxyphenol + O2 + 4 H+ = 2-octaprenyl-6-methoxy-1,4-benzoquinol + H2O. GO:0008691 3-hydroxybutyryl-CoA dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008691 MetaCyc:3-HYDROXYBUTYRYL-COA-DEHYDROGENASE-RXN|RHEA:16197|EC:1.1.1.157 BHBD activity|beta-hydroxybutyryl-CoA dehydrogenase activity|L-(+)-3-hydroxybutyryl-CoA dehydrogenase activity|(S)-3-hydroxybutanoyl-CoA:NADP+ oxidoreductase activity|dehydrogenase, L-3-hydroxybutyryl coenzyme A (nicotinamide adenine dinucleotide phosphate)|L(+)-3-hydroxybutyryl-CoA dehydrogenase activity|beta-hydroxybutyryl coenzyme A dehydrogenase activity Catalysis of the reaction: (S)-3-hydroxybutanoyl-CoA + NADP+ = 3-acetoacetyl-CoA + NADPH + H+. CHEBI:58255 aldehydo-D-galactose 6-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58255 CHEBI:83211 tirucallane triterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83211 GO:0008690 3-deoxy-manno-octulosonate cytidylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008690 RHEA:23448|EC:2.7.7.38|MetaCyc:CPM-KDOSYNTH-RXN 2-keto-3-deoxyoctonate cytidylyltransferase activity|3-deoxy-D-manno-octulosonate cytidylyltransferase activity|CMP-2-keto-3-deoxyoctulosonic acid synthetase activity|CTP:3-deoxy-D-manno-octulosonate cytidylyltransferase activity|CTP:3-deoxy-manno-octulosonate cytidylyltransferase activity|CMP-3-deoxy-D-manno-octulosonate pyrophosphorylase activity|CMP-3-deoxy-D-manno-octulosonate synthetase activity|CMP-3-deoxy-D-manno-octulosonate diphosphorylase activity|CMP-KDO synthetase activity|CTP:CMP-3-deoxy-D-manno-octulosonate cytidylyltransferase activity|cytidine monophospho-3-deoxy-D-manno-octulosonate pyrophosphorylase activity Catalysis of the reaction: CTP + 3-deoxy-D-manno-octulosonate = diphosphate + CMP-3-deoxy-D-manno-octulosonate. CHEBI:58254 quercetin 3-sulfate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58254 CHEBI:58253 (S)-norcoclaurinium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58253 CHEBI:58252 S-methyl-L-methionine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58252 CHEBI:58251 N,N-dimethylglycine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58251 GO:0018007 N-terminal peptidyl-glycine N-glucuronylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018007 RESID:AA0058 The glucuronylation of the N-terminal glycine of proteins to form the derivative D-glucuronyl-N-glycine. GO:0018006 N-terminal protein amino acid glucuronylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018006 The glucuronylation of the N-terminal amino acid of proteins. GO:0018009 N-terminal peptidyl-L-cysteine N-palmitoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018009 RESID:AA0060 The covalent attachment of a palmitoyl group to a nitrogen (N) atom in an N-terminal cysteine residue to form N-palmitoyl-L-cysteine. GO:0018008 N-terminal peptidyl-glycine N-myristoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018008 RESID:AA0059 N-terminal peptidyl-glycine N-myristylation The myristoylation of the N-terminal glycine of proteins to form the derivative N-myristoyl-glycine. GO:0018003 peptidyl-lysine N6-acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018003 RESID:AA0055 The acetylation of the peptidyl-lysine of proteins to form the derivative peptidyl-N6-acetyl-L-lysine. GO:0033644 host cell membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033644 Double layer of lipid molecules as it encloses host cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0018002 N-terminal peptidyl-glutamic acid acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018002 RESID:AA0044 The acetylation of the N-terminal glutamic acid of proteins to form the derivate acetyl-glutamic acid. GO:0033643 host cell part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0033643 Any constituent part of a host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0033642 modulation by symbiont of host response to gravitational stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033642 response to gravitational stimulus Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0018005 N-terminal peptidyl-glycine N-formylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018005 RESID:AA0057 The formylation of the N-terminal glycine of proteins to form the derivative N-formylglycine. GO:0018004 N-terminal protein formylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018004 The formylation of the N-terminal amino acid of proteins. GO:0033641 modulation by symbiont of host response to pH biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033641 Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0033640 modulation by symbiont of host response to osmotic stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033640 Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:58259 dihydrostreptomycin 3'alpha,6-bisphosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58259 GO:0018001 N-terminal peptidyl-valine acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018001 RESID:AA0054 The acetylation of the N-terminal tyrosine of proteins to form the derivative N-acetyl-L-valine. CHEBI:58257 S-(4-bromophenyl)-L-cysteine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58257 GO:0018000 N-terminal peptidyl-tyrosine acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018000 RESID:AA0053 The acetylation of the N-terminal tyrosine of proteins to form the derivative N-acetyl-L-tyrosine. CHEBI:58256 alpha-cyclopiazonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58256 GO:0033639 modulation by symbiont of host response to water biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033639 Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0033638 modulation by symbiont of host response to heat biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033638 response to heat shock Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0033637 modulation by symbiont of host response to cold biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033637 freezing tolerance Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0033636 modulation by symbiont of host response to temperature stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033636 modulation by symbiont of host response to thermal stimulus Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0033635 modulation by symbiont of host response to abiotic stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033635 Any process in which an organism modulates a change in the state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0033634 positive regulation of cell-cell adhesion mediated by integrin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033634 positive regulation of cell-cell adhesion mediated by integrin complex Any process that activates or increases the frequency, rate, or extent of cell-cell adhesion mediated by integrin. GO:0008699 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008699 CHEBI:83229 amino acid opine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83229 GO:0008698 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008698 GO:0008697 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008697 EC:5.3.1.17|RHEA:23896|MetaCyc:5.3.1.17-RXN|KEGG_REACTION:R04383 4-deoxy-L-threo-5-hexulose uronate isomerase activity|5-keto-4-deoxyuronate isomerase activity|4-deoxy-L-threo-5-hexosulose-uronate aldose-ketose-isomerase activity Catalysis of the reaction: 5-dehydro-4-deoxy-D-glucuronate = 3-deoxy-D-glycero-2,5-hexodiulosonate. CHEBI:83228 L-alpha-amino acid residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83228 GO:0008696 4-amino-4-deoxychorismate lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008696 EC:4.1.3.38|KEGG_REACTION:R05553|RHEA:16201|MetaCyc:ADCLY-RXN para-aminobenzoic acid (PABA) synthase|enzyme X activity|p-aminobenzoate synthetase|4-amino-4-deoxychorismate pyruvate-lyase activity|ADC lyase activity|aminodeoxychorismate lyase activity|4-amino-4-deoxychorismate pyruvate-lyase (4-aminobenzoate-forming)|para-aminobenzoic acid synthase Catalysis of the reaction: 4-amino-4-deoxychorismate = 4-aminobenzoate + H(+) + pyruvate. GO:0008695 3-phenylpropionate dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008695 RHEA:20357|EC:1.14.12.19|UM-BBD_enzymeID:e0307|MetaCyc:HCAMULTI-RXN HcaA1A2CD|3-phenylpropanoate,NADH:oxygen oxidoreductase (2,3-hydroxylating) activity|3-phenylpropanoate dioxygenase activity|Hca dioxygenase activity Catalysis of the reaction: 3-phenylpropionate + NADH + H+ + O2 = NAD+ + cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol. CHEBI:83226 N(omega)-phospho-L-arginine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83226 GO:0008694 3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008694 EC:4.1.1.98|RHEA:27778|MetaCyc:3-OCTAPRENYL-4-OHBENZOATE-DECARBOX-RXN 3-polyprenyl-4-hydroxybenzoate carboxy-lyase activity|3-octaprenyl-4-hydroxybenzoate decarboxylase activity|PPHB decarboxylase activity|UbiD|3-polyprenyl 4-hydroxybenzoate decarboxylase activity|polyprenyl p-hydroxybenzoate decarboxylase activity|UbiX Catalysis of the reaction: 3-octaprenyl-4-hydroxy benzoate = 2-octaprenylphenol + CO2. GO:0008693 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008693 EC:4.2.1.59|RHEA:41860 beta-hydroxyacyl-acyl carrier protein dehydratase activity|FabA|D-3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity|3-hydroxydecanoyl-acyl-carrier-protein dehydratase activity|3-hydroxydecanoyl-[acyl-carrier protein] dehydratase activity|beta-hydroxyacyl-ACP dehydrase activity|beta-hydroxydecanoyl thiol ester dehydrase activity|D-3-hydroxydecanoyl-acyl-carrier-protein dehydratase activity|3-hydroxydecanoyl-ACP dehydratase activity|3-hydroxydecanoyl-acyl carrier protein dehydrase activity|HDDase activity|(3R)-3-hydroxydecanoyl-acyl-carrier-protein hydro-lyase activity|beta-hydroxydecanoate dehydrase activity|3-hydroxydecanoyl-acyl carrier protein dehydratase activity|beta-hydroxydecanoyl thioester dehydrase activity Catalysis of the reaction: (3R)-3-hydroxydecanoyl-[acyl-carrier protein] = 2,3-decenoyl-[acyl-carrier protein] or 3,4-decenoyl-[acyl-carrier protein] + H2O. CHEBI:83224 beta-D-glucosyl-L-erythro-N-acylsphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83224 CHEBI:83223 L-erythro-N-acylsphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83223 GO:0008692 3-hydroxybutyryl-CoA epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008692 MetaCyc:OHBUTYRYL-COA-EPIM-RXN|RHEA:21760|EC:5.1.2.3 3-hydroxyacyl-CoA epimerase activity|3-hydroxybutyryl coenzyme A epimerase activity|3-hydroxybutanoyl-CoA 3-epimerase activity Catalysis of the reaction: (S)-3-hydroxybutanoyl-CoA = (R)-3-hydroxybutanoyl-CoA. CHEBI:58244 nocardicin A(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58244 CHEBI:58243 5'-adenylyl sulfate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58243 CHEBI:58242 Renilla luciferyl sulfate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58242 CHEBI:58241 N(2)-(3-carboxylatopropionyl)-L-arginine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58241 GO:0018018 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018018 CHEBI:58240 aspulvinone E(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58240 GO:0018017 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018017 GO:0018019 N-terminal peptidyl-glutamine methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018019 RESID:AA0071 The methylation of a glutamine residue in proteins to form the peptidyl-N5-methyl-L-glutamine derivative. GO:0018014 N-terminal peptidyl-methionine methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018014 RESID:AA0064 The methylation of the N-terminal methionine of proteins to form the derivative N-methyl-L-methionine. GO:0033633 negative regulation of cell-cell adhesion mediated by integrin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033633 negative regulation of cell-cell adhesion mediated by integrin complex Any process that stops, prevents, or reduces the frequency, rate, or extent of cell-cell adhesion mediated by integrin. GO:0033632 regulation of cell-cell adhesion mediated by integrin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033632 regulation of cell-cell adhesion mediated by integrin complex Any process that modulates the frequency, rate, or extent of cell-cell adhesion mediated by integrin. GO:0018013 N-terminal peptidyl-glycine methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018013 RESID:AA0063 The methylation of the N-terminal glycine of proteins to form the derivative N-methylglycine. GO:0018016 N-terminal peptidyl-proline dimethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018016 RESID:AA0066 The methylation of the N-terminal proline of proteins to form the derivative N,N-dimethyl-L-proline. GO:0033631 cell-cell adhesion mediated by integrin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033631 cell-cell adhesion mediated by integrin complex The attachment of one cell to another cell via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits. GO:0033630 positive regulation of cell adhesion mediated by integrin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033630 positive regulation of cell adhesion mediated by integrin complex Any process that activates or increases the frequency, rate, or extent of cell adhesion mediated by integrin. GO:0018015 N-terminal peptidyl-phenylalanine methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018015 RESID:AA0065 The methylation of the N-terminal phenylalanine of proteins to form the derivative N-methyl-L-phenylalanine. CHEBI:58249 (S,S,S)-nicotianamine trizwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58249 GO:0018010 glycoprotein N-palmitoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018010 MetaCyc:GLYCOPROTEIN-N-PALMITOYLTRANSFERASE-RXN mucus glycoprotein fatty acyltransferase|palmitoyl-CoA:glycoprotein N-palmitoyltransferase activity Catalysis of the reaction: palmitoyl-CoA + glycoprotein = CoA + N-palmitoylglycoprotein. CHEBI:58248 2,3-bisphosphonato-D-glycerate(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58248 CHEBI:58247 beta-D-glucose 6-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58247 GO:0018012 N-terminal peptidyl-alanine trimethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018012 RESID:AA0062 The trimethylation of the N-terminal alanine of proteins to form the derivative peptidyl-N,N,N-trimethyl-L-alanine. CHEBI:58246 sulfonatoacetaldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58246 CHEBI:58245 2'-deoxyadenosine 5'-monophosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58245 GO:0018011 N-terminal peptidyl-alanine methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018011 RESID:AA0062|RESID:AA0061 The methylation of the N-terminal alanine of proteins. GO:0033629 negative regulation of cell adhesion mediated by integrin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033629 negative regulation of cell adhesion mediated by integrin complex Any process that stops, prevents, or reduces the frequency, rate, or extent of cell adhesion mediated by integrin. GO:0033628 regulation of cell adhesion mediated by integrin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033628 regulation of cell adhesion mediated by integrin complex Any process that modulates the frequency, rate, or extent of cell adhesion mediated by integrin. GO:0033627 cell adhesion mediated by integrin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033627 cell adhesion mediated by integrin complex The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits. GO:0033626 positive regulation of integrin activation by cell surface receptor linked signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033626 cell surface receptor linked signal transduction leading to integrin complex activation|cell surface receptor linked signal transduction leading to integrin activation Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell that lead to the increased affinity of an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits, for its extracellular ligands. GO:0033625 positive regulation of integrin activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033625 positive regulation of integrin complex activation Any process that activates or increases the frequency, rate, or extent of integrin activation. GO:0008669 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008669 GO:0008668 (2,3-dihydroxybenzoyl)adenylate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008668 EC:2.7.7.58|RHEA:20229|KEGG_REACTION:R01504|MetaCyc:DHBAMPLIG-RXN 2,3-dihydroxybenzoate-AMP ligase activity|ATP:2,3-dihydroxybenzoate adenylyltransferase activity Catalysis of the reaction: 2,3-dihydroxybenzoate + ATP = 2,3-dihydroxybenzoyl 5'-adenylate + diphosphate. GO:0033624 negative regulation of integrin activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033624 negative regulation of integrin complex activation Any process that stops, prevents, or reduces the frequency, rate, or extent of integrin activation. GO:0008667 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008667 MetaCyc:DHBDEHYD-RXN|EC:1.3.1.28|KEGG_REACTION:R01505|RHEA:23824 2,3-DHB dehydrogenase activity|2,3-dihydro-2,3-dihydroxybenzoate:NAD+ oxidoreductase activity Catalysis of the reaction: (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + NAD(+) = 2,3-dihydroxybenzoate + H(+) + NADH. GO:0033623 regulation of integrin activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033623 regulation of integrin complex activation Any process that modulates the frequency, rate, or extent of integrin activation. GO:0008666 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008666 KEGG_REACTION:R04365|RHEA:17325|EC:2.3.1.117|MetaCyc:TETHYDPICSUCC-RXN succinyl-CoA:2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity|succinyl-CoA:tetrahydrodipicolinate N-succinyltransferase activity|THDP N-succinyltransferase activity|tetrahydrodipicolinate succinyltransferase activity|tetrahydrodipicolinate N-succinyltransferase activity|succinyl-CoA:(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity|tetrahydropicolinate succinylase activity|tetrahydrodipicolinate succinylase activity Catalysis of the reaction: (S)-2,3,4,5-tetrahydrodipicolinate + H(2)O + succinyl-CoA = L-2-succinylamino-6-oxopimelate + CoA. GO:0008665 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008665 RO:0003001 produced by biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0003001 RO:0003001 a produced_by b iff some process that occurs_in b has_output a. GO:0008664 2'-5'-RNA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008664 2'-5' RNA ligase activity Catalysis of the formation of a phosphodiester bond between the 2'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another. CHEBI:83239 1,2-dibutyryl-sn-glycero-3-phospho-(1'D-myo-inositol-5'-phosphate) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83239 GO:0008663 2',3'-cyclic-nucleotide 2'-phosphodiesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008663 RHEA:19621|EC:3.1.4.16|MetaCyc:CYCPHOSDIESTER-RXN 2':3'-cyclic nucleotide phosphodiesterase:3'-nucleotidase activity|ribonucleoside 2',3'-cyclic phosphate diesterase activity|2',3'-cyclic nucleotidase activity|2',3'-cyclic nucleoside monophosphate phosphodiesterase|2',3 '-cyclic AMP phosphodiesterase activity|2':3'-cyclic phosphodiesterase activity|2',3'-cyclic nucleotide phosphohydrolase|cyclic 2',3'-nucleotide 2'-phosphodiesterase activity|2',3'-cyclic AMP 2'-phosphohydrolase activity|cyclic phosphodiesterase:3'-nucleotidase activity|nucleoside-2',3'-cyclic-phosphate 3'-nucleotidohydrolase activity|cyclic 2',3'-nucleotide phosphodiesterase Catalysis of the reaction: nucleoside 2',3'-cyclic phosphate + H2O = nucleoside 3'-phosphate. PR:000020320 insulin receptor proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000020320 INSR/ClvPrd An insulin receptor that has been processed by proteolytic cleavage. GO:0008662 1-phosphofructokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008662 RHEA:14213|MetaCyc:1PFRUCTPHOSN-RXN|EC:2.7.1.56 ATP:D-fructose-phosphate 6-phosphotransferase activity|fructose-1-phosphate kinase activity|phosphofructokinase 1|1-phosphofructokinase (phosphorylating)|fructose 1-phosphate kinase activity|D-fructose-1-phosphate kinase activity Catalysis of the reaction: ATP + D-fructose 1-phosphate = ADP + D-fructose 1,6-bisphosphate. CHEBI:83237 acylglycerophosphoacylglycerol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83237 GO:0008661 1-deoxy-D-xylulose-5-phosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008661 MetaCyc:DXS-RXN|EC:2.2.1.7|RHEA:12605|KEGG_REACTION:R05636 DXP-synthase activity|1-deoxyxylulose-5-phosphate synthase activity|1-deoxy-D-xylulose-5-phosphate pyruvate-lyase (carboxylating) activity|DOXP synthase activity|pyruvate:D-glyceraldehyde-3-phosphate acetaldehydetransferase (decarboxylating) Catalysis of the reaction: D-glyceraldehyde 3-phosphate + H(+) + pyruvate = 1-deoxy-D-xylulose 5-phosphate + CO(2). CHEBI:83236 2-acylglycerophospho-(2'-acylglycerol)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83236 GO:0008660 1-aminocyclopropane-1-carboxylate deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008660 EC:3.5.99.7|KEGG_REACTION:R00997|UM-BBD_reactionID:r0357|RHEA:16933|MetaCyc:4.1.99.4-RXN 1-aminocyclopropane carboxylic acid deaminase activity|ACC deaminase activity|1-aminocyclopropane-1-carboxylate aminohydrolase (isomerizing)|1-aminocyclopropane-1-carboxylate endolyase (deaminating) activity Catalysis of the reaction: 1-aminocyclopropane-1-carboxylate + H(2)O = 2-oxobutanate + NH(4)(+). RO:0003000 produces biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0003000 RO:0003000 a produces b if some process that occurs_in a has_output b, where a and b are material entities. Examples: hybridoma cell line produces monoclonal antibody reagent; chondroblast produces avascular GAG-rich matrix. CHEBI:83235 beta-D-galactosyl-(1<->1')-sphinganine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83235 CHEBI:83234 beta-D-galactosyl-(1<->1')-sphinganine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83234 CHEBI:58233 UDP-L-iduronate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58233 CHEBI:83233 Mo(=O)(=S)-molybdopterin cofactor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83233 CHEBI:58232 D-glucose 1,6-bisphosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58232 CHEBI:58231 CTP(3-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58231 CHEBI:58230 2-(beta-D-glucopyranosyluronate)-D-glucuronate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58230 GO:0033622 integrin activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033622 integrin complex assembly|integrin complex activation The aggregation, arrangement and bonding together of an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits, that lead to the increased affinity of the integrin for its extracellular ligands. GO:0033621 nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033621 mRNA degradation, meiosis-specific transcripts|degradation of meiosis-specific transcripts|mRNA breakdown, meiosis-specific transcripts|mRNA catabolism, meiosis-specific transcripts|nuclear mRNA catabolic process, meiosis-specific transcripts The chemical reactions and pathways resulting in the selective degradation of meiosis-specific transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein. CHEBI:58239 16-hydroxytabersoninium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58239 GO:0033620 Mei2 nuclear dot complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033620 Mei2 dot|Mei2 nuclear dot|nuclear body A ribonucleoprotein complex that forms during meiotic prophase in a fixed position in the horsetail nucleus; contains Mei2 and meiRNA. May play a role in the progression of meiosis I. CHEBI:58238 4-methoxy-1-methyl-2-oxo-1,2-dihydropyridine-3-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58238 CHEBI:58237 cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58237 CHEBI:58236 N-feruloylglycinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58236 CHEBI:2394 acetochlor biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_2394 CHEBI:58234 3-hydroxyquininium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58234 GO:0033619 membrane protein proteolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033619 The proteolytic cleavage of a transmembrane protein leading to the release of its intracellular or ecto-domains. GO:0033618 plasma membrane respiratory chain complex IV assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033618 plasma membrane cytochrome c oxidase complex assembly|plasma membrane cytochrome c oxidase biogenesis The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the plasma membrane. GO:0033617 mitochondrial cytochrome c oxidase assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033617 mitochondrial cytochrome c oxidase complex assembly|mitochondrial cytochrome c oxidase biogenesis|mitochondrial respiratory chain complex IV assembly The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the mitochondrial inner membrane. GO:0033616 plasma membrane proton-transporting ATP synthase complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033616 The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the plasma membrane. GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033615 The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the mitochondrial inner membrane. PR:000020311 insulin proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000020311 INS/ClvPrd An insulin that has been processed by proteolytic cleavage. GO:0033614 chloroplast proton-transporting ATP synthase complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033614 The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the chloroplast thylakoid membrane. GO:0033613 activating transcription factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033613 transcription activator binding Interacting selectively and non-covalently with an activating transcription factor, any protein whose activity is required to initiate or upregulate transcription. GO:0008679 2-hydroxy-3-oxopropionate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008679 EC:1.1.1.60|MetaCyc:TSA-REDUCT-RXN|RHEA:18841 tartronate semialdehyde reductase (NADPH) activity|(R)-glycerate:NAD(P)+ oxidoreductase activity Catalysis of the reaction: (R)-glycerate + NADP+ = 2-hydroxy-3-oxopropanoate + NADPH + H+. GO:0008678 2-deoxy-D-gluconate 3-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008678 MetaCyc:KDUD-RXN|RHEA:12160|EC:1.1.1.125 2-keto-3-deoxygluconate oxidoreductase activity|2-deoxy-D-gluconate:NAD+ 3-oxidoreductase activity|2-deoxygluconate dehydrogenase activity Catalysis of the reaction: 2-deoxy-D-gluconate + NAD+ = 3-dehydro-2-deoxy-D-gluconate + NADH + H+. GO:0033612 receptor serine/threonine kinase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033612 transmembrane receptor protein serine/threonine kinase ligand binding Interacting selectively and non-covalently with a receptor that possesses protein serine/threonine kinase activity. GO:0008677 2-dehydropantoate 2-reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008677 KEGG_REACTION:R02472|RHEA:16233|EC:1.1.1.169|MetaCyc:2-DEHYDROPANTOATE-REDUCT-RXN 2-oxopantoate reductase activity|2-ketopantoate reductase activity|ketopantoate reductase activity|(R)-pantoate:NADP+ 2-oxidoreductase activity|2-ketopantoic acid reductase activity|KPA reductase activity|ketopantoic acid reductase activity Catalysis of the reaction: (R)-pantoate + NADP(+) = 2-dehydropantoate + H(+) + NADPH. GO:0043003 positive regulation of Golgi to plasma membrane CFTR protein transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043003 upregulation of Golgi to plasma membrane CFTR protein transport|up regulation of Golgi to plasma membrane CFTR protein transport|activation of Golgi to plasma membrane CFTR protein transport|stimulation of Golgi to plasma membrane CFTR protein transport|up-regulation of Golgi to plasma membrane CFTR protein transport Any process that activates or increases the frequency, rate or extent of transport of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein from the Golgi to the plasma membrane. GO:0008676 3-deoxy-8-phosphooctulonate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008676 MetaCyc:KDO-8PSYNTH-RXN|EC:2.5.1.55|KEGG_REACTION:R03254|RHEA:14053 KDO-8-phosphate synthetase activity|phosphoenolpyruvate:D-arabinose-5-phosphate C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming)|3-deoxy-D-mannooctulosonate-8-phosphate synthetase activity|KDOP synthase activity|2-keto-3-deoxy-8-phosphooctonic synthetase activity|2-dehydro-3-deoxy-phosphooctonate aldolase activity|3-deoxyoctulosonic 8-phosphate synthetase activity|phospho-2-keto-3-deoxyoctonate aldolase activity|3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase activity|2-dehydro-3-deoxy-D-octonate-8-phosphate D-arabinose-5-phosphate-lyase (pyruvate-phosphorylating) activity|2-dehydro-3-deoxyphosphooctonate aldolase activity|3-deoxy-D-manno-octulosonate-8-phosphate synthase activity|KDO-8-P synthase activity Catalysis of the reaction: D-arabinose 5-phosphate + H(2)O + phosphoenolpyruvate = 8-phospho-3-deoxy-D-manno-oct-2-ulosonate + 2 H(+) + phosphate. GO:0043002 negative regulation of Golgi to plasma membrane CFTR protein transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043002 down regulation of Golgi to plasma membrane CFTR protein transport|downregulation of Golgi to plasma membrane CFTR protein transport|down-regulation of Golgi to plasma membrane CFTR protein transport|inhibition of Golgi to plasma membrane CFTR protein transport Any process that stops, prevents, or reduces the frequency, rate or extent of transport of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein from the Golgi to the plasma membrane. GO:0008675 2-dehydro-3-deoxy-phosphogluconate aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008675 EC:4.1.2.14|MetaCyc:KDPGALDOL-RXN|RHEA:17089 ODPG aldolase activity|2-dehydro-3-deoxy-D-gluconate-6-phosphate D-glyceraldehyde-3-phosphate-lyase activity|2-keto-3-deoxygluconate-6-P-aldolase activity|KDPG-aldolase activity|2-dehydro-3-deoxy-D-gluconate-6-phosphate D-glyceraldehyde-3-phosphate-lyase (pyruvate-forming)|2-keto-3-deoxygluconate-6-phosphate aldolase activity|6-phospho-2-keto-3-deoxygluconate aldolase activity|2-keto-3-deoxy-6-phosphogluconic aldolase activity|2-oxo-3-deoxy-6-phosphogluconate aldolase activity|phospho-2-keto-3-deoxygluconic aldolase activity|phospho-2-keto-3-deoxygluconate aldolase activity|phospho-2-dehydro-3-deoxygluconate aldolase activity|2-keto-3-deoxy-6-phosphogluconate aldolase activity|KDPG aldolase activity Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate 6-phosphate = pyruvate + D-glyceraldehyde 3-phosphate. GO:0043005 neuron projection biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0043005 NIF_Subcellular:sao867568886 neuron protrusion|neurite|neuronal cell projection|nerve fiber|neuron process A prolongation or process extending from a nerve cell, e.g. an axon or dendrite. GO:0008674 2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008674 EC:4.1.2.21|MetaCyc:DEHYDDEOXPHOSGALACT-ALDOL-RXN|RHEA:24464|KEGG_REACTION:R01064 2-keto-3-deoxy-6-phosphogalactonic aldolase activity|2-oxo-3-deoxygalactonate 6-phosphate aldolase activity|phospho-2-keto-3-deoxygalactonic aldolase activity|6-phospho-2-dehydro-3-deoxygalactonate aldolase activity|2-dehydro-3-deoxy-D-galactonate-6-phosphate D-glyceraldehyde-3-phosphate-lyase activity|(KDPGal)aldolase activity|2-dehydro-3-deoxy-D-galactonate-6-phosphate D-glyceraldehyde-3-phosphate-lyase (pyruvate-forming)|2-dehydro-3-deoxyphosphogalactonate aldolase activity|2-keto-3-deoxy-6-phosphogalactonic acid aldolase activity|6-phospho-2-keto-3-deoxygalactonate aldolase activity|phospho-2-keto-3-deoxygalactonate aldolase activity Catalysis of the reaction: 6-phospho-2-dehydro-3-deoxy-D-galactonate = D-glyceraldehyde 3-phosphate + pyruvate. GO:0043004 cytoplasmic sequestering of CFTR protein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043004 cytoplasmic sequestering of cystic fibrosis transmembrane conductance regulator protein|storage of CFTR (cystic fibrosis transmembrane conductance regulator) protein in cytoplasm|retention of CFTR (cystic fibrosis transmembrane conductance regulator) protein in cytoplasm|sequestering of CFTR (cystic fibrosis transmembrane conductance regulator protein) in cytoplasm|cytoplasmic sequestration of CFTR (cystic fibrosis transmembrane conductance regulator protein)|maintenance of CFTR protein location in cytoplasm|sequestration of CFTR (cystic fibrosis transmembrane conductance regulator protein) in cytoplasm|cytoplasmic retention of CFTR (cystic fibrosis transmembrane conductance regulator) protein|cytoplasmic storage of CFTR (cystic fibrosis transmembrane conductance regulator) protein The selective interaction of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein with specific molecules in the cytoplasm, thereby inhibiting its transport to the cell membrane. CHEBI:83249 N-(2-hydroxyacyl)-beta-D-galactosylsphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83249 CHEBI:83248 N-(2-hydroxyhexanoyl)sphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83248 GO:0008673 2-dehydro-3-deoxygluconokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008673 EC:2.7.1.45|MetaCyc:DEOXYGLUCONOKIN-RXN|KEGG_REACTION:R01541|RHEA:14797 2-keto-3-deoxygluconokinase (phosphorylating)|ATP:2-dehydro-3-deoxy-D-gluconate 6-phosphotransferase activity|2-keto-3-deoxygluconate kinase activity|3-deoxy-2-oxo-D-gluconate kinase activity|ketodeoxygluconokinase activity|2-keto-3-deoxygluconokinase activity|2-keto-3-deoxy-D-gluconic acid kinase activity|KDG kinase activity Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate + ATP = 2-dehydro-3-deoxy-6-phospho-D-gluconate + ADP + 2 H(+). CHEBI:83247 N-(2-hydroxyacyl)sphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83247 GO:0008672 2-dehydro-3-deoxyglucarate aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008672 MetaCyc:KDGALDOL-RXN|EC:4.1.2.20|RHEA:10268 2-dehydro-3-deoxy-D-glucarate tartronate-semialdehyde-lyase (pyruvate-forming)|2-keto-3-deoxyglucarate aldolase activity|alpha-keto-beta-deoxy-D-glucarate aldolase activity|2-dehydro-3-deoxy-D-glucarate tartronate-semialdehyde-lyase activity Catalysis of the reaction: 2-dehydro-3-deoxy-D-glucarate = pyruvate + tartronate semialdehyde. CHEBI:83246 N-(2-hydroxyhexanoyl)-beta-D-galactosylsphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83246 GO:0008671 2-dehydro-3-deoxygalactonokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008671 EC:2.7.1.58|RHEA:16525|KEGG_REACTION:R03387|MetaCyc:DEHYDDEOXGALACTKIN-RXN 2-keto-3-deoxygalactonokinase activity|2-keto-3-deoxygalactonate kinase (phosphorylating)|2-keto-3-deoxy-galactonokinase activity|2-oxo-3-deoxygalactonate kinase activity|ATP:2-dehydro-3-deoxy-D-galactonate 6-phosphotransferase activity Catalysis of the reaction: 2-dehydro-3-deoxy-D-galactonate + ATP = 6-phospho-2-dehydro-3-deoxy-D-galactonate + ADP + 2 H(+). GO:0043001 Golgi to plasma membrane protein transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043001 The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane. CHEBI:83245 N-(2-hydroxyacyl)-beta-D-galactosylsphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83245 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008670 EC:1.3.1.34|RHEA:12136|MetaCyc:DIENOYLCOAREDUCT-RXN 4-enoyl-CoA reductase (NADPH2)|4-enoyl-CoA reductase activity|4-enoyl coenzyme A (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|trans-2,3-didehydroacyl-CoA:NADP+ 4-oxidoreductase activity|4-enoyl-CoA reductase (NADPH) activity Catalysis of the reaction: trans-2,3-didehydroacyl-CoA + NADP+ = trans,trans-2,3,4,5-tetradehydroacyl-CoA + NADPH + H+. GO:0043000 Golgi to plasma membrane CFTR protein transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043000 Golgi to plasma membrane cystic fibrosis transmembrane conductance regulator protein transport The directed movement of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein from the Golgi to the plasma membrane. GO:0008680 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008680 CHEBI:83244 N-(2-hydroxyhexanoyl)sphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83244 CHEBI:58222 4-hydroxy-2-oxopentanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58222 CHEBI:83243 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1D-myo-inositol 3,4,5-triphosphate)(7-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83243 CHEBI:83242 1D-myo-inositol 1,3-biphosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83242 CHEBI:58220 N-adenylyl-L-phenylalanate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58220 CHEBI:83241 1D-myo-inositol 3,4-biphosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83241 GO:0043007 maintenance of rDNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043007 rDNA maintenance|ribosomal DNA maintenance Any process involved in sustaining the fidelity and copy number of rDNA repeats. CHEBI:83240 1,2-dibutyryl-sn-glycero-3-phospho-(1'D-myo-inositol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83240 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043006 calcium-dependent phospholipase A2 activation|activation of phospholipase A2 activity by calcium-mediated signalling|calcium-dependent activation of phospholipase A2 A series of molecular signals that leads to the upregulation of calcium-dependent phospholipase A2 activity in response to the signal. GO:0043009 chordate embryonic development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043009 The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching. GO:0043008 ATP-dependent protein binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0043008 Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) using energy from the hydrolysis of ATP. GO:0033611 oxalate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033611 ethanedioate catabolic process|oxalate degradation|oxalate breakdown|ethanedioic acid catabolic process|oxalate catabolism|oxalic acid catabolic process The chemical reactions and pathways resulting in the breakdown of oxalate, the organic acid ethanedioate. GO:0033610 oxalate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033610 ethanedioate biosynthetic process|oxalic acid biosynthetic process|oxalate anabolism|ethanedioic acid biosynthetic process|oxalate synthesis|oxalate formation|oxalate biosynthesis The chemical reactions and pathways resulting in the formation of oxalate, the organic acid ethanedioate. CHEBI:58229 Watasenia luciferin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58229 CHEBI:58228 carbamoyl phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58228 CHEBI:58227 5-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58227 CHEBI:58226 L-ribulose 5-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58226 CHEBI:58225 alpha-D-glucose 6-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58225 CHEBI:58224 GDP-6-deoxy-alpha-D-mannose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58224 CHEBI:58223 UDP(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58223 GO:0033608 formyl-CoA transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033608 MetaCyc:RXN0-1382|EC:2.8.3.16|RHEA:16545|KEGG_REACTION:R07290 formyl-CoA:oxalate CoA-transferase activity|formyl-coenzyme A transferase activity|formyl-CoA oxalate CoA-transferase activity Catalysis of the reaction: formyl-CoA + oxalate = formate + oxalyl-CoA. GO:0033607 SOD1-Bcl-2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033607 A heterodimeric protein complex formed of superoxide dismutase 1 and Bcl-2. Complex formation is thought to link superoxide dismutase to an apoptotic pathway. GO:0033606 chemokine receptor transport within lipid bilayer biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033606 chemokine receptor translocation within membrane The directed movement of a chemokine receptor within a lipid bilayer. GO:0008649 rRNA methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008649 Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an rRNA molecule. GO:0033605 positive regulation of catecholamine secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033605 up-regulation of catecholamine secretion|upregulation of catecholamine secretion|up regulation of catecholamine secretion|activation of catecholamine secretion|stimulation of catecholamine secretion Any process that activates or increases the frequency, rate or extent of the regulated release of a catecholamine. GO:0033604 negative regulation of catecholamine secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033604 inhibition of catecholamine secretion|down regulation of catecholamine secretion|downregulation of catecholamine secretion|down-regulation of catecholamine secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a catecholamine. GO:0008648 obsolete tachykinin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008648 tachykinin OBSOLETE. A family of hormones that stimulate secretion of saliva and cause smooth muscle contraction and vasodilation. GO:0033603 positive regulation of dopamine secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033603 upregulation of dopamine secretion|stimulation of dopamine secretion|up-regulation of dopamine secretion|activation of dopamine secretion|up regulation of dopamine secretion Any process that activates or increases the frequency, rate or extent of the regulated release of dopamine. GO:0008647 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008647 GO:0033602 negative regulation of dopamine secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033602 down regulation of dopamine secretion|inhibition of dopamine secretion|down-regulation of dopamine secretion|downregulation of dopamine secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of dopamine. GO:0008646 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008646 GO:0008645 hexose transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008645 hexose transport|high-affinity hexose transport|low-affinity hexose transport|hexose membrane transport The process in which hexose is transported across a membrane. Hexoses are any aldoses with a chain of six carbon atoms in the molecule. GO:0033601 positive regulation of mammary gland epithelial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033601 up-regulation of mammary gland epithelial cell proliferation|upregulation of mammary gland epithelial cell proliferation|up regulation of mammary gland epithelial cell proliferation|activation of mammary gland epithelial cell proliferation|stimulation of mammary gland epithelial cell proliferation Any process that activates or increases the rate or extent of mammary gland epithelial cell proliferation. GO:0043014 alpha-tubulin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043014 alpha tubulin binding Interacting selectively and non-covalently with the microtubule constituent protein alpha-tubulin. GO:0008644 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008644 GO:0008643 carbohydrate transport biolink:BiologicalProcess go-plus goslim_yeast|goslim_pir http://purl.obolibrary.org/obo/GO_0008643 sugar transport The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are any of a group of organic compounds based of the general formula Cx(H2O)y. GO:0043013 negative regulation of fusion of sperm to egg plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043013 down regulation of fusion of sperm to egg plasma membrane|inhibition of fusion of sperm to egg plasma membrane|negative regulation of sperm-oocyte fusion|down-regulation of fusion of sperm to egg plasma membrane|downregulation of fusion of sperm to egg plasma membrane|inhibition of sperm-oocyte fusion Any process that stops or prevents the binding and fusion of a sperm to the oocyte plasma membrane. GO:0008642 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008642 GO:0043016 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043016 GO:0008641 ubiquitin-like modifier activating enzyme activity biolink:MolecularActivity go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0008641 small protein activating enzyme activity Catalysis of the activation of small proteins, such as ubiquitin or ubiquitin-like proteins, through the formation of an ATP-dependent high-energy thiolester bond. GO:0043015 gamma-tubulin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043015 gamma tubulin binding Interacting selectively and non-covalently with the microtubule constituent protein gamma-tubulin. GO:0043010 camera-type eye development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043010 The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field. GO:0008640 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008640 CHEBI:48891 thiazolidinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48891 CHEBI:83257 N-(2-hydroxyhexanoyl)-beta-D-galactosylsphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83257 GO:0043012 regulation of fusion of sperm to egg plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043012 regulation of sperm-oocyte fusion Any process that modulates the binding and fusion of a sperm to the oocyte plasma membrane. GO:0033609 oxalate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033609 ethanedioic acid metabolic process|oxalic acid metabolic process|oxalate metabolism|ethanedioate metabolic process The chemical reactions and pathways involving oxalate, the organic acid ethanedioate. GO:0043011 myeloid dendritic cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043011 Wikipedia:Dendritic_cell The process in which a monocyte acquires the specialized features of a dendritic cell, an immunocompetent cell of the lymphoid and hemopoietic systems and skin. CHEBI:58211 dolichyl beta-D-mannosyl phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58211 CHEBI:58210 FMN(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58210 CHEBI:10275 (9Z,11E,13E)-octadeca-9,11,13-trienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_10275 GO:0043018 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043018 GO:0043017 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043017 GO:0043019 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043019 CHEBI:10278 alpha-eudesmol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_10278 GO:0033600 negative regulation of mammary gland epithelial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033600 inhibition of mammary gland epithelial cell proliferation|down regulation of mammary gland epithelial cell proliferation|downregulation of mammary gland epithelial cell proliferation|down-regulation of mammary gland epithelial cell proliferation Any process that stops, prevents or reduces the rate or extent of mammary gland epithelial cell proliferation. CHEBI:58219 mevaldate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58219 CHEBI:58218 9-riburonosylhypoxanthine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58218 OBO:GOCHE_25512 substance with neurotransmitter role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_25512 CHEBI:58217 pentachlorophenolate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58217 CHEBI:58215 guanosine 3',5'-bis(diphosphate)(6-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58215 CHEBI:58214 kanamycin A(4+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58214 CHEBI:58213 ammonioacetaldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58213 CHEBI:58212 dUTP(3-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58212 CHEBI:48887 bile acid metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48887 GO:0008659 (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008659 EC:4.2.1.59|RHEA:41892 (3R)-hydroxymyristoyl-[acyl-carrier protein] dehydratase activity|(3R)-hydroxymyristoyl-ACP dehydratase activity Catalysis of the reaction: (3R)-3-hydroxytetradecanoyl-[acyl-carrier protein] = tetradecenoyl-[acyl-carrier protein] + H2O. GO:0008658 penicillin binding biolink:MolecularActivity go-plus goslim_metagenomics http://purl.obolibrary.org/obo/GO_0008658 Interacting selectively and non-covalently with penicillin, any antibiotic that contains the condensed beta-lactamthiazolidine ring system. GO:0008657 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008657 DNA gyrase inhibitor activity Stops, prevents or reduces the activity of ATP-hydrolyzing DNA topoisomerase. ATP-hydrolyzing DNA topoisomerase catalyzes the DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2. CHEBI:58209 4-(3-methylbut-2-enyl)-L-tryptophan zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58209 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008656 Reactome:R-HSA-205117|Reactome:R-HSA-449073 caspase activator activity Increases the rate of proteolysis catalyzed by a cysteine-type endopeptidase involved in the apoptotic process. GO:0043025 neuronal cell body biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0043025 NIF_Subcellular:sao1044911821|Wikipedia:Soma_(biology) neuron cell body|neuronal cell soma The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites. GO:0008655 pyrimidine-containing compound salvage biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0008655 pyrimidine salvage Any process that generates a pyrimidine-containing compound, any nucleobase, nucleoside, nucleotide or nucleic acid that contains a pyrimidine base, from derivatives of them without de novo synthesis. GO:0008654 phospholipid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008654 MetaCyc:PHOSLIPSYN2-PWY|MetaCyc:LIPASYN-PWY|MetaCyc:PHOSLIPSYN-PWY phospholipid biosynthesis|phospholipid anabolism|phospholipid synthesis|phospholipid formation The chemical reactions and pathways resulting in the formation of phospholipids, any lipid containing phosphoric acid as a mono- or diester. GO:0043024 ribosomal small subunit binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043024 Interacting selectively and non-covalently with any part of the small ribosomal subunit. GO:0008653 lipopolysaccharide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008653 LPS metabolic process|lipopolysaccharide metabolism The chemical reactions and pathways involving lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide. GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043027 caspase inhibitor activity Stops, prevents or reduces the activity of a cysteine-type endopeptidase involved in the apoptotic process. GO:0008652 cellular amino acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008652 Wikipedia:Amino_acid_synthesis cellular amino acid biosynthesis|cellular amino acid anabolism|amino acid biosynthetic process|cellular amino acid synthesis|cellular amino acid formation The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents. GO:0043026 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043026 GO:0043021 ribonucleoprotein complex binding biolink:MolecularActivity go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0043021 protein-RNA complex binding|RNP binding|ribonucleoprotein binding Interacting selectively and non-covalently with any complex of RNA and protein. GO:0008651 obsolete actin polymerizing activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008651 actin polymerizing activity OBSOLETE. (Was not defined before being made obsolete). GO:0008650 rRNA (uridine-2'-O-)-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008650 Reactome:R-HSA-6793127 Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methyluridine. GO:0043020 NADPH oxidase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043020 respiratory-burst oxidase|flavocytochrome b558 A enzyme complex of which the core is a heterodimer composed of a light (alpha) and heavy (beta) chain, and requires several other water-soluble proteins of cytosolic origin for activity. Functions in superoxide generation by the NADPH-dependent reduction of O2. GO:0043023 ribosomal large subunit binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043023 Interacting selectively and non-covalently with any part of the larger ribosomal subunit. GO:0043022 ribosome binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043022 ribosome receptor activity Interacting selectively and non-covalently with any part of a ribosome. CHEBI:48882 (R)-atropine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48882 CHEBI:58200 N(5)-methyl-L-glutamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58200 CHEBI:83264 beta-D-glucosylceramide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83264 GO:0043029 T cell homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043029 T lymphocyte homeostasis|T-cell homeostasis|T-lymphocyte homeostasis The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. CHEBI:83262 alkyl,acyl-3-(beta-D-galactosyl)-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83262 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043028 caspase regulator activity Modulates the activity of a cysteine-type endopeptidase involved in the apoptotic process. CHEBI:58207 5-methyltetrahydropteroyltri-L-glutamate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58207 CHEBI:58206 all-trans-heptaprenyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58206 CHEBI:58205 3-nitroacrylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58205 CHEBI:58203 2-formylbenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58203 CHEBI:58202 N(6)-methyl-L-lysinium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58202 CHEBI:58201 6,7-dimethyl-8-(1-D-ribityl)lumazine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58201 GO:0008629 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008629 CHEBI:48873 cholinergic antagonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48873 GO:0008628 hormone-mediated apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008628 induction of apoptosis by hormones|apoptotic signaling pathway in response to hormone A series of molecular signals mediated by the detection of a hormone, and which triggers the apoptotic signaling pathway in a cell. The pathway starts with reception of a hormone signal, and ends when the execution phase of apoptosis is triggered. GO:0043030 regulation of macrophage activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043030 regulation of macrophage polarization Any process that modulates the frequency or rate of macrophage activation. CHEBI:48876 muscarinic antagonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48876 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008627 induction of apoptosis by ionic changes A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to changes in intracellular ion homeostasis, and ends when the execution phase of apoptosis is triggered. GO:0008626 granzyme-mediated apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008626 apoptotic signaling pathway in response to granzyme|induction of apoptosis by granzyme A series of molecular signals induced by granzymes which triggers the apoptotic death of a cell. The pathway starts with reception of a granzyme signal, and ends when the execution phase of apoptosis is triggered. Granzymes are serine proteases that are secreted by cytotoxic T cells and natural killer cells to induce apoptosis in target cells. CHEBI:48878 nicotinic antagonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48878 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008625 induction of apoptosis via death domain receptors|death receptor-mediated apoptosis|induction of apoptosis via death receptors A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with a ligand binding to a death domain receptor on the cell surface, and ends when the execution phase of apoptosis is triggered. GO:0008624 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008624 GO:0008623 CHRAC biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0008623 chromatin accessibility complex|ISW2 complex An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2H in mammals, Isw2 in S. cerevisiae), an ACF1 homolog, and additional small histone fold subunits (generally two of these, but Xenopus has only one and some additional non-conserved subunits). CHRAC plays roles in the regulation of RNA polymerase II transcription and in DNA replication and repair. GO:0008622 epsilon DNA polymerase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0008622 DNA polymerase epsilon complex A heterotetrameric DNA polymerase complex that catalyzes processive DNA synthesis in the absence of PCNA, but is further stimulated in the presence of PCNA. The complex contains a large catalytic subunit and three small subunits, and is best characterized in Saccharomyces, in which the subunits are named Pol2p, Dpb2p, Dpb3p, and Dpb4p. Some evidence suggests that DNA polymerase epsilon is the leading strand polymerase; it is also involved in nucleotide-excision repair and mismatch repair. GO:0043036 starch grain biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043036 starch granule Plant storage body for amylose and amylopectin, 1-100um in diameter. Also contains small amounts of enzymes, amino acids, lipids and nucleic acids. The shape of the grain varies widely amongst species, but is often spherical or disk-shaped. GO:0043035 chromatin insulator sequence binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043035 Interacting selectively and non-covalently and stoichiometrically with a chromatin insulator sequence, a DNA sequence that prevents enhancer-mediated activation or repression of transcription. GO:0008621 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008621 GO:0043038 amino acid activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043038 The modification of an amino acid to an active form, for incorporation into a peptide, protein or other macromolecule. GO:0008620 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008620 GO:0043037 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0043037 GO:0043032 positive regulation of macrophage activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043032 up regulation of macrophage activation|activation of macrophage activation|stimulation of macrophage activation|up-regulation of macrophage activation|positive regulation of macrophage polarization|upregulation of macrophage activation Any process that stimulates, induces or increases the rate of macrophage activation. CHEBI:48870 idaric acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48870 GO:0043031 negative regulation of macrophage activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043031 downregulation of macrophage activation|down-regulation of macrophage activation|inhibition of macrophage activation|negative regulation of macrophage polarization|down regulation of macrophage activation Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage activation. GO:0043034 costamere biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0043034 Wikipedia:Costamere Regular periodic sub membranous arrays of vinculin in skeletal and cardiac muscle cells, these arrays link Z-discs to the sarcolemma and are associated with links to extracellular matrix. GO:0043033 isoamylase complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0043033 debranching enzyme complex A protein complex whose composition varies amongst species; in rice it probably exists in a homo-tetramer to homo-hexamer form and in Gram-negative bacteria as a dimer. Functions in the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages. CHEBI:48871 galactaric acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48871 CHEBI:83276 (2E,6E)-farnesoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83276 CHEBI:83274 juvenile hormone III carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83274 CHEBI:83273 N-acylsphingoid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83273 GO:0043039 tRNA aminoacylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043039 tRNA charging|aminoacyl-tRNA biosynthetic process|aminoacyl-tRNA biosynthesis The chemical reactions and pathways by which the various amino acids become bonded to their corresponding tRNAs. The most common route for synthesis of aminoacyl tRNA is by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, usually catalyzed by the cognate aminoacyl-tRNA ligase. A given aminoacyl-tRNA ligase aminoacylates all species of an isoaccepting group of tRNA molecules. CHEBI:34227 2,3-di-O-phytanyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_34227 CHEBI:48863 phycocyanobilin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48863 GO:0043041 amino acid activation for nonribosomal peptide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043041 nonribosomal amino acid activation Activation of an amino acid for incorporation into a peptide by a nonribosomal process. GO:0008639 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008639 GO:0043040 tRNA aminoacylation for nonribosomal peptide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043040 tRNA aminoacylation for nonribosomal peptide formation|tRNA aminoacylation for nonribosomal peptide biosynthesis|tRNA aminoacylation for nonribosomal peptide anabolism|tRNA aminoacylation for nonribosomal peptide synthesis The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in nonribosomal peptide synthesis. GO:0008638 obsolete protein tagging activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008638 protein tagging activity OBSOLETE. Covalent addition of a specific tagging molecule to a protein, targeting the tagged protein for some fate e.g. degradation. CHEBI:48867 4-(trimethylammonio)but-2-enoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48867 GO:0008637 apoptotic mitochondrial changes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008637 The morphological and physiological alterations undergone by mitochondria during apoptosis. GO:0008636 obsolete activation of caspase activity by protein phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008636 caspase activation via phosphorylation|activation of caspase activity by protein amino acid phosphorylation|activation of caspase activity by protein phosphorylation OBSOLETE. Upregulation of the activity of a caspase, any of a group of cysteine proteases involved in apoptosis, by the addition of a phosphate group. GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008635 activation of caspase activity by cytochrome c|caspase activation via cytochrome c Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process and is mediated by cytochrome c. CHEBI:48869 3-O-(geranylgeranyl)glycerol 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48869 GO:0008634 obsolete negative regulation of survival gene product expression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008634 negative regulation of survival gene products|down-regulation of survival gene product activity|inhibition of survival gene product activity|downregulation of survival gene product activity|negative regulation of survival gene product expression|down regulation of survival gene product activity|negative regulation of survival gene product activity OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of survival gene product expression; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level. CHEBI:48868 sn-1-O-(geranylgeranyl)glycerol 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48868 PR:000020357 insulin-like growth factor I proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000020357 IGF1/ClvPrd An insulin-like growth factor I that has been processed by proteolytic cleavage. GO:0043047 single-stranded telomeric DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0043047 telomeric ssDNA binding Interacting selectively and non-covalently with single-stranded telomere-associated DNA. GO:0008633 obsolete activation of pro-apoptotic gene products biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008633 activation of pro-apoptotic gene products|induction of pro-apoptotic gene products OBSOLETE. The conversion of proteins that induce or sustain apoptosis to an active form. GO:0043046 DNA methylation involved in gamete generation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043046 de novo DNA methylation The covalent transfer of a methyl group to C-5 of cytosine that contributes to the establishment of DNA methylation patterns in the gamete. GO:0008632 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008632 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008631 induction of apoptosis by oxidative stress|oxidative stress-induced intrinsic apoptotic signaling pathway A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, and ends when the execution phase of apoptosis is triggered. GO:0043049 otic placode formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043049 The initial developmental process that will lead to the formation of the vertebrate inner ear. The otic placode forms as a thickening of the head ectoderm adjacent to the developing hindbrain. GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008630 DNA damage response, signal transduction resulting in induction of apoptosis A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the detection of DNA damage, and ends when the execution phase of apoptosis is triggered. GO:0043048 dolichyl monophosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043048 dolichyl monophosphate anabolism|dolichyl monophosphate biosynthesis|dolichyl monophosphate synthesis|dolichyl monophosphate formation The chemical reactions and pathways resulting in the formation of dolichyl diphosphate, a phosphorylated dolichol derivative. GO:0043043 peptide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043043 peptide anabolism|peptide synthesis|peptide formation|peptide biosynthesis The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide. GO:0043042 amino acid adenylylation by nonribosomal peptide synthase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043042 amino acid adenylation by NRPS|amino acid adenylation by nonribosomal peptide synthase Activation of an amino acid for incorporation into a peptide by a nonribosomal process, catalyzed by subunits of nonribosomal peptide synthase. The amino acid is adenylated at its carboxylate group (ATP-dependent) then transferred to the thiol group of an enzyme-bound phosphopantetheine cofactor. GO:0043045 DNA methylation involved in embryo development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043045 de novo DNA methylation The covalent transfer of a methyl group to C-5 of cytosine that contributes to the epigenetic regulation of embryonic gene expression. CHEBI:48861 2-trans,6-trans,10-trans-geranylgeranyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48861 GO:0043044 ATP-dependent chromatin remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0043044 ATP-dependent chromatin remodelling Dynamic structural changes to eukaryotic chromatin that require energy from the hydrolysis of ATP, ranging from local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation, mediated by ATP-dependent chromatin-remodelling factors. CHEBI:34238 2,4-dibromophenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_34238 CHEBI:10280 (E,E)-alpha-farnesene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_10280 CHEBI:83280 flavone C-glycoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83280 CHEBI:10283 2-hydroxy fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_10283 GO:0018094 protein polyglycylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018094 RESID:AA0201 The addition of glycyl units covalently bound to the gamma carboxyl group peptidyl-glutamic acid. GO:0018093 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018093 GO:0018096 peptide cross-linking via S-(2-aminovinyl)-D-cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018096 RESID:AA0204 The synthesis of (S,Z)-S-(2-aminovinyl)cysteine forming an intra-polypeptide cross-link between serine and cysteine. GO:0018095 protein polyglutamylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018095 RESID:AA0202 The addition of one or more alpha-linked glutamyl units to the gamma carboxyl group of peptidyl-glutamic acid. GO:0018090 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018090 GO:0018092 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018092 GO:0018091 peptidyl-asparagine racemization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018091 RESID:AA0196 The racemization of peptidyl-asparagine. GO:0018087 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018087 GO:0018086 obsolete alanine racemization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018086 alanine racemization OBSOLETE. (Was not defined before being made obsolete). GO:0018089 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018089 GO:0018088 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018088 GO:0018097 protein-chromophore linkage via peptidyl-S-4-hydroxycinnamyl-L-cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018097 RESID:AA0207 protein amino acid cinnamylation The synthesis of the chromophore S-4-hydroxycinnamyl-L-cysteine. GO:0018072 peptidyl-L-glutamyl 5-glycerylphosphorylethanolamine biosynthetic process from peptidyl-glutamic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018072 RESID:AA0170 peptidyl-L-glutamyl 5-glycerylphosphorylethanolamine anabolism from peptidyl-glutamic acid|peptidyl-L-glutamyl 5-glycerylphosphorylethanolamine synthesis from peptidyl-glutamic acid|peptidyl-L-glutamyl 5-glycerylphosphorylethanolamine formation from peptidyl-glutamic acid The modification of peptidyl-glutamic acid residues by the covalent attachment of ethanolamine, itself further modified by the addition of a phosphoglycerol unit. GO:0018071 NAD(P)-cysteine ADP-ribosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018071 Catalysis of the reaction: NAD(P)+ + L-cysteine = nicotinamide + N2-(ADP-D-ribosyl)-L-cysteine. GO:0018074 peptidyl-histidine bromination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018074 RESID:AA0173 The bromination of peptidyl-histidine to form peptidyl-L-bromohistidine; the position of the bromine substitution is unknown. GO:0018073 protein bromination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018073 protein amino acid bromination The addition of one or more bromine atoms to an amino acid residue in a protein. GO:0018070 peptidyl-serine phosphopantetheinylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018070 RESID:AA0150 The phosphopantetheinylation of peptidyl-serine to form peptidyl-O-phosphopantetheine-L-serine. GO:0018069 peptide cross-linking via 4'-(L-tryptophan)-L-tryptophyl quinone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018069 RESID:AA0149 The cross-linking of a tryptophan residue to tryptophyl quinone to form 4'-(L-tryptophan)-L-tryptophyl quinone, a cofactor found at the active site of methylamine dehydrogenase. GO:0018068 peptidyl-L-2',4',5'-topaquinone biosynthetic process from peptidyl-tyrosine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018068 RESID:AA0147 peptidyl-L-2',4',5'-topaquinone formation from peptidyl-tyrosine|peptidyl-L-2',4',5'-topaquinone synthesis from peptidyl-tyrosine|peptidyl-L-2',4',5'-topaquinone anabolism from peptidyl-tyrosine The modification of protein tyrosine to L-2',4',5'-topaquinone, characteristic of the active site of copper amine oxidases. GO:0018065 obsolete protein-cofactor linkage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018065 OBSOLETE. The covalent attachment of a cofactor to a protein. GO:0018064 protein-histidine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018064 RHEA:19369|MetaCyc:2.1.1.85-RXN|EC:2.1.1.85 peptidyl-histidine N-methyltransferase activity|protein methylase IV activity|S-adenosyl methionine:protein-histidine N-methyltransferase activity|S-adenosyl-L-methionine:protein-L-histidine N-tele-methyltransferase activity|actin-specific histidine methyltransferase activity|protein (histidine) methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + protein L-histidine = S-adenosyl-L-homocysteine + protein N-methyl-L-histidine. GO:0018067 peptidyl-L-3',4'-dihydroxyphenylalanine biosynthetic process from peptidyl-tyrosine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018067 RESID:AA0146 peptidyl-L-3',4'-dihydroxyphenylalanine formation from peptidyl-tyrosine|peptidyl-L-3',4'-dihydroxyphenylalanine synthesis from peptidyl-tyrosine|peptidyl-L-3',4'-dihydroxyphenylalanine anabolism from peptidyl-tyrosine The modification of protein tyrosine to peptidyl-L-3',4'-dihydroxyphenylalanine (DOPA). CHEBI:73841 lysophosphatidylcholine (P-16:0/0:0) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73841 GO:0018083 peptidyl-L-3-oxoalanine biosynthetic process from peptidyl-cysteine or peptidyl-serine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018083 RESID:AA0185 peptidyl-L-3-oxoalanine anabolism from peptidyl-cysteine or peptidyl-serine|peptidyl-L-3-oxoalanine synthesis from peptidyl-cysteine or peptidyl-serine|peptidyl-L-3-oxoalanine formation from peptidyl-cysteine or peptidyl-serine The modification of peptidyl-cysteine or peptidyl-serine to peptidyl-L-3-oxoalanine; characteristic of the active sites of arylsulfatases. GO:0018082 peptidyl-(Z)-dehydrobutyrine biosynthetic process from peptidyl-threonine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018082 RESID:AA0182 peptidyl-(Z)-dehydrobutyrine anabolism from peptidyl-threonine|peptidyl-(Z)-dehydrobutyrine synthesis from peptidyl-threonine|peptidyl-(Z)-dehydrobutyrine formation from peptidyl-threonine The formation of (Z)-dehydrobutyrine by the dehydration of peptidyl-threonine. GO:0018085 peptidyl-L-amino acid racemization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018085 The process of conversion of a L-amino acid into its enantiomer, the corresponding D-amino acid. GO:0018084 peptidyl-lactic acid biosynthetic process from peptidyl-serine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018084 RESID:AA0186 peptidyl-lactic acid formation from peptidyl-serine|peptidyl-lactic acid synthesis from peptidyl-serine|peptidyl-lactic acid anabolism from peptidyl-serine The modification of N-terminal peptidyl-serine to lactic acid. GO:0018081 peptide cross-linking via lanthionine or 3-methyl-lanthionine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018081 RESID:AA0112|RESID:AA0111|RESID:AA0110 peptide cross-linking via the thiolethers lanthionine or 3-methyl-lanthionine|peptide cross-linking via the thioethers lanthionine or 3-methyl-lanthionine The synthesis of (2R,6R)-lanthionine, sn-(2S,6R)-lanthionine or (2S,3S,6R)-3-methyl-lanthionine, forming an intra-polypeptide cross-link between peptidyl-cysteine, and peptidyl-serine or peptidyl-threonine; dehydration of the serine or threonine residue to the alpha,beta-unsaturated amino acid is the first step; a bond then forms between the ethylene (ethene) group thus formed and the sulfur atom of a cysteine, with the inversion of the configuration of the alpha carbon of the serine or threonine occurring during the process. GO:0018080 peptidyl-tryptophan bromination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018080 RESID:AA0179 The bromination of peptidyl-tryptophan, to form peptidyl-L-6'-bromotryptophan. GO:0033691 sialic acid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033691 N-acetylneuraminic acid binding Interacting selectively and non-covalently with sialic acid, any of a variety of N- or O- substituted derivatives of neuraminic acid, a nine carbon monosaccharide. Sialic acids often occur in polysaccharides, glycoproteins, and glycolipids in animals and bacteria. GO:0033690 positive regulation of osteoblast proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033690 upregulation of osteoblast proliferation|stimulation of osteoblast proliferation|up-regulation of osteoblast proliferation|activation of osteoblast proliferation|up regulation of osteoblast proliferation Any process that activates or increases the rate or extent of osteoblast proliferation. GO:0033699 DNA 5'-adenosine monophosphate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033699 DNA 5'-adenylate hydrolase activity|DNA de-adenylation|DNA adenylate hydrolysis activity|AMP-removal activity|DNA deadenylation Catalysis of the reaction: 5'-AMP-DNA + H2O = AMP + DNA; nucleophilic release of a covalently linked adenylate residue from a DNA strand, leaving a 5' phosphate terminus. GO:0018079 protein halogenation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018079 protein amino acid halogenation The addition of a halogen to a protein amino acid. GO:0033698 Rpd3L complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033698 Rpd3C(L)|Clr6L complex|Clr6 histone deacetylase complex I/I' A histone deacetylase complex which deacetylates histones preferentially in promoter regions. Composed of a catalytic histone deacetylase subunit, an Sds-3 family protein, a SIN3 family co-repressor, a WD repeat protein, and a zf- PHD finger (Clr6, Sds3, Pst1, Prw1, Png2 in Schizosaccharomyces pombe; Rpd3p, Sin3p, Ume1p, Pho23p, Sap30p, Sds3p, Cti6p, Rxt2p, Rxt3p, Dep1p, Ume6p and Ash1p in Saccharomyces cerevisiae). GO:0033697 positive regulation of extent of heterochromatin assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033697 positive regulation of heterochromatin spreading|positive regulation of extent of heterochromatin formation Any process that increases the extent of heterochromatin formation; increases the size of a chromosomal region converted to heterochromatin. GO:0033696 negative regulation of extent of heterochromatin assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033696 negative regulation of extent of heterochromatin formation|maintenance of heterochromatin boundaries|negative regulation of heterochromatin spreading Any process that reduces the extent of heterochromatin formation; reduces the size of a chromosomal region converted to heterochromatin. GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033695 EC:1.17.5.- Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a quinone or similar acceptor molecule. GO:0018076 N-terminal peptidyl-lysine acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018076 The acetylation of the N-terminal lysine of proteins. GO:0018075 peptidyl-phenylalanine bromination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018075 RESID:AA0176|RESID:AA0175|RESID:AA0174 The bromination of phenylalanine. GO:0033694 oxidoreductase activity, acting on the CH-NH group of donors, iron-sulfur protein as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033694 EC:1.5.7.- Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces an iron-sulfur protein. GO:0018078 peptidyl-thyronine iodination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018078 RESID:AA0178|RESID:AA0177 The iodination of peptidyl-thyronine, formed from tyrosine. GO:0033693 neurofilament bundle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033693 NF bundle assembly The assembly of neurofilaments into bundles, in which the filaments are longitudinally oriented, with numerous crossbridges between them. Neurofilament bundles may be cross-linked to each other, to membrane-bounded organelles or other cytoskeletal structures such as microtubules. GO:0033692 cellular polysaccharide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033692 cellular polysaccharide anabolism|cellular polysaccharide synthesis|cellular polysaccharide formation|cellular polysaccharide biosynthesis|cellular glycan biosynthetic process|cellular glycan biosynthesis The chemical reactions and pathways resulting in the formation of polysaccharides, polymers of many (typically more than 10) monosaccharide residues linked glycosidically, occurring at the level of an individual cell. GO:0018077 protein iodination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018077 protein amino acid iodination The addition of one or more iodine atoms to an amino acid residue in a protein. GO:0018050 C-terminal peptidyl-threonine amidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018050 RESID:AA0097 The formation of a C-terminal peptidyl-threonine amide by hydrolysis and oxidation of an interior Thr-Gly peptide in a secreted protein. CHEBI:73852 (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73852 CHEBI:73851 1-[(9Z)-hexadecenoyl]-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73851 GO:0018052 C-terminal peptidyl-tyrosine amidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018052 RESID:AA0099 The formation of a C-terminal peptidyl-tyrosine amide by hydrolysis and oxidation of an interior Tyr-Gly peptide in a secreted protein. GO:0018051 C-terminal peptidyl-tryptophan amidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018051 RESID:AA0098 The formation of a C-terminal peptidyl-tryptophan amide by hydrolysis and oxidation of an interior Trp-Gly peptide in a secreted protein. CHEBI:73856 (7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73856 CHEBI:73858 1-stearoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73858 GO:0033689 negative regulation of osteoblast proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033689 down-regulation of osteoblast proliferation|downregulation of osteoblast proliferation|down regulation of osteoblast proliferation|inhibition of osteoblast proliferation Any process that stops, prevents or reduces the rate or extent of osteoblast proliferation. CHEBI:73857 (9Z,12Z,15Z,18Z)-3-oxotetracosatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73857 GO:0033680 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0033680 CHEBI:58299 3-dehydrosphinganinium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58299 CHEBI:58298 6-phosphonato-2-dehydro-3-deoxy-D-galactate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58298 CHEBI:58297 glutathione disulfide(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58297 CHEBI:58296 4-methyl-5-(2-phosphonatooxyethyl)thiazole(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58296 CHEBI:58295 S-acetylcysteaminium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58295 CHEBI:58294 beta-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3-(beta-N-acetylneuraminyl-2,6)-N-acetyl-D-galactosaminyl(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58294 CHEBI:58293 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine betaine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58293 CHEBI:58292 (S)-naringenin(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_58292 GO:0018047 C-terminal peptidyl-phenylalanine amidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018047 RESID:AA0094 The formation of a C-terminal peptidyl-phenylalanine amide by hydrolysis and oxidation of an interior Phe-Gly peptide in a secreted protein. GO:0033688 regulation of osteoblast proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033688 Any process that modulates the frequency, rate or extent of osteoblast proliferation. GO:0033687 osteoblast proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033687 The multiplication or reproduction of osteoblasts, resulting in the expansion of an osteoblast cell population. An osteoblast is a bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone. GO:0018046 C-terminal peptidyl-methionine amidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018046 RESID:AA0093 The formation of a C-terminal peptidyl-methionine amide by hydrolysis and oxidation of an interior Met-Gly peptide in a secreted protein. GO:0018049 C-terminal peptidyl-serine amidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018049 RESID:AA0096 The formation of a C-terminal peptidyl-serine amide by hydrolysis and oxidation of an interior Ser-Gly peptide in a secreted protein. GO:0033686 positive regulation of luteinizing hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033686 up-regulation of luteinizing hormone secretion|upregulation of luteinizing hormone secretion|up regulation of luteinizing hormone secretion|activation of luteinizing hormone secretion|stimulation of luteinizing hormone secretion Any process that activates or increases the frequency, rate or extent of the regulated release of luteinizing hormone. GO:0033685 negative regulation of luteinizing hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033685 inhibition of luteinizing hormone secretion|down regulation of luteinizing hormone secretion|downregulation of luteinizing hormone secretion|down-regulation of luteinizing hormone secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of luteinizing hormone. GO:0018048 C-terminal peptidyl-proline amidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018048 RESID:AA0095 The formation of a C-terminal peptidyl-proline amide by hydrolysis and oxidation of an interior Pro-Gly peptide in a secreted protein. GO:0018043 C-terminal peptidyl-isoleucine amidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018043 RESID:AA0090 The formation of a C-terminal peptidyl-isoleucine amide by hydrolysis and oxidation of an interior Ile-Gly peptide in a secreted protein. GO:0033684 regulation of luteinizing hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033684 Any process that modulates the frequency, rate or extent of the regulated release of luteinizing hormone. GO:0018042 C-terminal peptidyl-histidine amidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018042 RESID:AA0089 The formation of a C-terminal peptidyl-histidine amide by hydrolysis and oxidation of an interior His-Gly peptide in a secreted protein. GO:0033683 nucleotide-excision repair, DNA incision biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033683 DNA incision involved in nucleotide-excision repair|nucleic acid cleavage involved in nucleotide-excision repair A process that results in the endonucleolytic cleavage of the damaged strand of DNA. The incision occurs at the junction of single-stranded DNA and double-stranded DNA that is formed when the DNA duplex is unwound. GO:0018045 C-terminal peptidyl-lysine amidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018045 RESID:AA0092 The formation of a C-terminal peptidyl-lysine amide by hydrolysis and oxidation of an interior Lys-Gly peptide in a secreted protein. GO:0033682 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0033682 CHEBI:73850 1-(1Z-hexadecenyl)-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73850 GO:0018044 C-terminal peptidyl-leucine amidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018044 RESID:AA0091 The formation of a C-terminal peptidyl-leucine amide by hydrolysis and oxidation of an interior Leu-Gly peptide in a secreted protein. GO:0033681 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0033681 GO:0018061 peptidyl-L-3-phenyllactic acid biosynthetic process from peptidyl-phenylalanine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018061 RESID:AA0128 peptidyl-L-3-phenyllactic acid anabolism from peptidyl-phenylalanine|peptidyl-L-3-phenyllactic acid synthesis from peptidyl-phenylalanine|peptidyl-L-3-phenyllactic acid formation from peptidyl-phenylalanine The modification of a N-terminal peptidyl-phenylalanine residue by either oxidative deamination or by transamination and subsequent reduction to form peptidyl-L-3-phenyllactic acid. CHEBI:73863 (7Z,10Z,13Z,16Z,19Z)-3-oxodocosapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73863 GO:0018060 N-terminal peptidyl-cysteine deamination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018060 The oxidative deamination of N-terminal peptidyl-cysteine to form pyruvic acid with an amide bond between its 1-carboxyl group and the N-terminal residue. CHEBI:73862 (5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73862 GO:0018063 cytochrome c-heme linkage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018063 RESID:AA0135|RESID:AA0134 cytochrome c-haem linkage The linkage of cytochromes and other heme proteins to heme. GO:0018062 peptidyl-tryptophan succinylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018062 RESID:AA0130 The modification of an N-terminal peptidyl-tryptophan residue to form peptidyl-N2-succinyl-L-tryptophan. GO:0033679 3'-5' DNA/RNA helicase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033679 3' to 5' DNA/RNA helicase activity|ATP-dependent 3' to 5' DNA/RNA helicase activity|ATP-dependent 3'-5' DNA/RNA helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of a DNA/RNA duplex in the direction 3' to 5'. GO:0033678 5'-3' DNA/RNA helicase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033678 Reactome:R-HSA-163120 5' to 3' DNA/RNA helicase activity|ATP-dependent 5'-3' DNA/RNA helicase activity|ATP-dependent 5' to 3' DNA/RNA helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of a DNA/RNA duplex in the direction 5' to 3'. CHEBI:58291 1D-1-guanidiniumyl-1-deoxy-3-dehydro-scyllo-inositol(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58291 CHEBI:58290 trypanothione(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58290 CHEBI:58287 heparosan-N-sulfate D-glucuronate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58287 CHEBI:58286 methyl-CoM(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58286 CHEBI:58285 7-methylguanosine 5'-phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58285 CHEBI:58284 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58284 CHEBI:58283 CDP-4-dehydro-3,6-dideoxy-D-glucose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58283 CHEBI:58282 1D-myo-inositol 1,4-bisphosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58282 GO:0033677 DNA/RNA helicase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0033677 ATP-dependent DNA/RNA helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of a DNA/RNA duplex, i.e. a double helix in which a strand of DNA pairs with a complementary strand of RNA. GO:0018058 N-terminal protein amino acid deamination, from amino carbon biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018058 RESID:AA0129|RESID:AA0128|RESID:AA0127 The oxidative deamination of the alpha carbon of an encoded N-terminal amino acid, to form pyruvic acid retaining an amide bond between its 1-carboxyl group and the adjacent residue. The pyruvate 2-oxo group may become an enzyme active site, or it may be reduced to an alcohol. GO:0018057 peptidyl-lysine oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018057 RESID:AA0121 The oxidation of the terminal amino-methylene groups of peptidyl-L-lysine or peptidyl-5-hydroxy-L-lysine to aldehyde groups to form allysine or hydroxyallysine residues, respectively; these are intermediates in the formation of covalent cross-links between adjacent polypeptide chains in proteins such as collagens. GO:0033676 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0033676 GO:0033675 pericanalicular vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033675 A membrane-bounded vesicle found near the apical, or pericanalicular, membrane of a hepatocyte; contains proteins involved in bile salt transport and other fluid and solute transport processes. GO:0033674 positive regulation of kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033674 kinase activator|up regulation of kinase activity|stimulation of kinase activity|up-regulation of kinase activity|upregulation of kinase activity Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. GO:0018059 N-terminal peptidyl-serine deamination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018059 The oxidative deamination of N-terminal peptidyl-serine to form pyruvic acid with an amide bond between its 1-carboxyl group and the N-terminal residue. GO:0033673 negative regulation of kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033673 down regulation of kinase activity|downregulation of kinase activity|kinase inhibitor|down-regulation of kinase activity|inhibition of kinase activity Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. GO:0018054 peptidyl-lysine biotinylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018054 RESID:AA0117 The covalent modification of peptidyl-lysine by biotin to form peptidyl-N6-biotinyl-L-lysine. GO:0033672 positive regulation of NAD+ kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033672 upregulation of NAD+ kinase activity|stimulation of NAD+ kinase activity|up-regulation of NAD+ kinase activity|NAD+ kinase activator|up regulation of NAD+ kinase activity Any process that activates or increases the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule. GO:0018053 C-terminal peptidyl-valine amidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018053 RESID:AA0100 The formation of a C-terminal peptidyl-valine amide by hydrolysis and oxidation of an interior Val-Gly peptide in a secreted protein. GO:0033671 negative regulation of NAD+ kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033671 downregulation of NAD+ kinase activity|NAD+ kinase inhibitor|down regulation of NAD+ kinase activity|inhibition of NAD+ kinase activity|down-regulation of NAD+ kinase activity Any process that stops, prevents, or reduces the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule. GO:0018056 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018056 GO:0033670 regulation of NAD+ kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033670 NAD kinase regulator|regulation of NAD kinase activity Any process that modulates the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule. GO:0018055 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0018055 CHEBI:58289 2-phosphonato-D-glycerate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58289 CHEBI:73874 (9Z,12Z,15Z,18Z)-3-oxotetracosatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73874 CHEBI:73873 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73873 GO:0018030 peptidyl-lysine N6-myristoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018030 Catalysis of the transfer of a myristoyl group to the N6 nitrogen atom on a lysine residue of a peptide or protein molecule. CHEBI:73876 (9Z,12Z,15Z,18Z,21Z)-3-oxotetracosapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73876 GO:0033669 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0033669 GO:0033668 negative regulation by symbiont of host apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033668 negative regulation by symbiont of host apoptosis|downregulation by organism of host apoptotic programmed cell death|down regulation by organism of host apoptotic programmed cell death|inhibition by organism of host apoptotic programmed cell death|down-regulation by organism of host apoptotic programmed cell death Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0033667 obsolete negative regulation of growth or development of symbiont in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033667 down-regulation of growth or development of organism within host|negative regulation of growth or development of symbiont in host|negative regulation of invasive growth|negative regulation of growth or development of symbiont within host|inhibition of growth of development of organism within host|down regulation of growth or development of organism within host|downregulation of growth or development of organism within host OBSOLETE. Any process by which the symbiont stops, prevents or reduces its increase in size or mass or its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction. CHEBI:58280 IDP(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58280 CHEBI:58277 dehydro-D-arabinono-1,4-lactone(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58277 CHEBI:58276 4-hydroxy-4-methyl-2-oxoglutarate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58276 CHEBI:58275 2-methylserine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58275 CHEBI:58274 L-gamma-glutamyl phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58274 CHEBI:58273 aldehydo-D-ribose 5-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58273 GO:0018029 peptidyl-lysine palmitoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018029 RESID:AA0077 The palmitoylation of peptidyl-lysine to form peptidyl-N6-palmitoyl-L-lysine. GO:0018028 peptidyl-lysine myristoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018028 RESID:AA0078 peptidyl-lysine myristylation The myristoylation of peptidyl-lysine to form peptidyl-N6-myristoyl-L-lysine. CHEBI:58272 3-phosphonato-D-glycerate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58272 CHEBI:58270 N-acetyl-L-leucinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58270 GO:0033666 obsolete positive regulation of growth or development of symbiont in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033666 positive regulation of growth or development of symbiont in host|positive regulation of invasive growth|positive regulation of growth or development of symbiont within host|up-regulation of growth or development of organism within host|upregulation of growth or development of organism within host|up regulation of growth or development of organism within host OBSOLETE. Any process by which the symbiont activates, maintains or increases its size or mass or its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction. GO:0018025 calmodulin-lysine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018025 RHEA:21556|EC:2.1.1.60|Reactome:R-HSA-6786205|MetaCyc:2.1.1.60-RXN S-adenosyl-L-methionine:calmodulin-L-lysine 6-N-methyltransferase activity|S-adenosylmethionine:calmodulin (lysine) N-methyltransferase activity|S-adenosyl-L-methionine:calmodulin-L-lysine N6-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + calmodulin L-lysine = S-adenosyl-L-homocysteine + calmodulin N6-methyl-L-lysine. GO:0033665 obsolete regulation of growth or development of symbiont in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033665 modulation of growth or development of organism within host|modulation of growth or development of symbiont within host|modulation of invasive growth|regulation of growth or development of symbiont in host|regulation of growth or development of symbiont within host OBSOLETE. Any process by which the symbiont regulates the increase in its size or mass, or its progression from an initial condition to a later condition, within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down. The host is defined as the larger of the organisms involved in the symbiotic interaction. GO:0018024 histone-lysine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018024 Reactome:R-HSA-5637686|Reactome:R-HSA-5638332|Reactome:R-HSA-5649800|EC:2.1.1.43|Reactome:R-HSA-4827382|Reactome:R-HSA-5423038|Reactome:R-HSA-5649802|Reactome:R-HSA-4827383|MetaCyc:HISTONE-LYSINE-N-METHYLTRANSFERASE-RXN|Reactome:R-HSA-5649801|Reactome:R-HSA-3788748|RHEA:10024|Reactome:R-HSA-3788745|Reactome:R-HSA-5634729|Reactome:R-HSA-5651654|Reactome:R-HSA-5638141|Reactome:R-HSA-5634802|Reactome:R-HSA-5649764|Reactome:R-HSA-5651657|RESID:AA0076|Reactome:R-HSA-5649799|RESID:AA0075|RESID:AA0074|Reactome:R-HSA-5159245|Reactome:R-HSA-5634750|Reactome:R-HSA-5638333|Reactome:R-HSA-5638157|Reactome:R-HSA-5244692 protein methylase III activity|histone-lysine N-methylase activity|S-adenosyl-L-methionine:histone-L-lysine N6-methyltransferase activity|S-adenosyl-L-methionine:histone-L-lysine 6-N-methyltransferase activity|protein methylase 3 activity|histone H1-specific S-adenosylmethionine:protein-lysine N-methyltransferase activity|protein methyltransferase II activity|protein (lysine) methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + histone L-lysine = S-adenosyl-L-homocysteine + histone N6-methyl-L-lysine. The methylation of peptidyl-lysine in histones forms N6-methyl-L-lysine, N6,N6-dimethyl-L-lysine and N6,N6,N6-trimethyl-L-lysine derivatives. GO:0033664 obsolete positive regulation by symbiont of host defense-related protein level biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033664 OBSOLETE. Any process in which the symbiont activates, maintains or increases levels of defense-related proteins in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0018027 peptidyl-lysine dimethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018027 RESID:AA0075 The methylation of peptidyl-lysine to form peptidyl-N6,N6-dimethyl-L-lysine. GO:0018026 peptidyl-lysine monomethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018026 RESID:AA0076 The methylation of peptidyl-lysine to form peptidyl-N6-methyl-L-lysine. GO:0033663 obsolete negative regulation by symbiont of host defense-related protein level biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033663 OBSOLETE. Any process in which the symbiont reduces of the levels of defense-related proteins in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0018021 peptidyl-histidine methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018021 RESID:AA0317|RESID:AA0073 The methylation of peptidyl-L-histidine to form peptidyl-L-1'-methyl-L-histidine (otherwise known as tau-methylhistidine, tele-methylhistidine) or peptidyl-L-3'-methyl-L-histidine (otherwise known as pi-methylhistidine, pros-methylhistidine). CHEBI:73870 (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73870 GO:0033662 obsolete modulation by symbiont of host defense-related protein level biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033662 OBSOLETE. The alternation by a symbiont of the levels of defense-related proteins in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0033661 effector-mediated defense to host-produced reactive oxygen species biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033661 negative regulation by organism of defense-related host respiratory burst|down regulation by organism of defense-related host metabolic burst|negative regulation by organism of defense-related host reactive oxygen intermediate production|negative regulation by organism of defense-related host ROI production|negative regulation by organism of defense-related host reactive oxidative species production|down-regulation by organism of defense-related host oxidative burst|negative regulation by organism of defense-related host ROS production|negative regulation by symbiont of defense-related host reactive oxygen species production|suppression by symbiont of defense-related host reactive oxygen species production|downregulation by organism of defense-related host AOS production|inhibition by organism of defense-related host active oxygen species production A process mediated by a molecule secreted by a symbiont that results in the suppression of reactive oxygen species produced by the host as part of its innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0018020 peptidyl-glutamic acid methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018020 The addition of a methyl group to a glutamic acid residue in a protein. CHEBI:58279 3-(3,4-dihydroxyphenyl)lactate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58279 GO:0033660 suppression by symbiont of host resistance gene-dependent defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033660 downregulation by symbiont of pathogen-race/host plant cultivar-specific resistance in symbiont|down regulation by symbiont of defense response in host by specific elicitors|suppression by symbiont of host resistance gene-dependent defense response|negative regulation by symbiont of host resistance gene-dependent defense response|inhibition by symbiont of host resistance gene-dependent defense response|down-regulation by symbiont of host gene-for-gene resistance Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the resistance gene-dependent defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0018023 peptidyl-lysine trimethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018023 RESID:AA0074 The methylation of peptidyl-lysine to form peptidyl-N6,N6,N6-trimethyl-L-lysine. CHEBI:73871 (9Z,12Z,15Z,18Z,21Z)-3-oxotetracosapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73871 GO:0018022 peptidyl-lysine methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018022 The methylation of peptidyl-lysine to form either the mono-, di- or trimethylated derivative. CHEBI:58278 D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58278 GO:0018041 C-terminal peptidyl-glycine amidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018041 RESID:AA0088 The formation of a C-terminal peptidyl-glycine acid amide by hydrolysis and oxidation of an interior Gly-Gly peptide in a secreted protein. CHEBI:73887 (7Z,10Z,13Z,16Z,19Z)-3-oxodocosapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73887 GO:0018040 C-terminal peptidyl-glutamic acid amidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018040 RESID:AA0087 The formation of a C-terminal peptidyl-glutamic acid amide by hydrolysis and oxidation of an interior Glu-Gly peptide in a secreted protein. CHEBI:73886 UDP-alpha-D-apiose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73886 GO:0033659 modification by symbiont of host mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033659 The process in which an organism effects a change in the structure or function of host cell mitochondria. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:73888 Gly-Asn biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73888 GO:0033658 modification by symbiont of host chloroplast thylakoid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033658 The process in which an organism effects a change in the structure or function of the host cell chloroplast thylakoid. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0033657 modification by symbiont of host chloroplast part biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033657 The process in which an organism effects a change in the structure or function of a component of the host cell chloroplast. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0033656 modification by symbiont of host chloroplast biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0033656 The process in which an organism effects a change in the structure or function of host cell chloroplasts. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:83203 1-stearoylglycerone 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83203 CHEBI:58266 5-hydroxy-L-tryptophan zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58266 PR:000009978 lactotransferrin biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000009978 LTF|LF|lactoferrin|talalactoferrin A protein that is a translation product of the human LTF gene or a 1:1 ortholog thereof. CHEBI:58265 2-hydroxy-3-oxosuccinate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58265 CHEBI:58264 4-ammoniobutanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58264 CHEBI:58263 N-acetylputrescinium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58263 CHEBI:58262 2-C-methyl-D-erythritol 4-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58262 GO:0018039 C-terminal peptidyl-glutamine amidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018039 RESID:AA0086 The formation of a C-terminal peptidyl-glutamine amide by hydrolysis and oxidation of an interior Gln-Gly peptide in a secreted protein. CHEBI:58261 methyl sulfate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58261 CHEBI:58260 N(6)-acetyl-L-lysine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58260 GO:0033655 host cell cytoplasm part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0033655 cytoplasm component Any constituent part of the host cell cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0018036 C-terminal peptidyl-asparagine amidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018036 RESID:AA0083 The formation of a C-terminal peptidyl-asparagine amide by hydrolysis and oxidation of an interior Asn-Gly peptide in a secreted protein. GO:0018035 C-terminal peptidyl-arginine amidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018035 RESID:AA0082 The formation of a C-terminal peptidyl-arginine amide by hydrolysis and oxidation of an interior Arg-Gly peptide in a secreted protein. GO:0033654 host cell chloroplast thylakoid membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033654 Any sac-like membranous structures (cisternae) in a chloroplast found in host cells, combined into stacks (grana) and present singly in the stroma (stroma thylakoids or frets) as interconnections between grana. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0033653 host cell chloroplast part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0033653 host chloroplast component Any constituent part of a chloroplast as it is found in host cells and which are a chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0018038 C-terminal peptidyl-cysteine amidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018038 RESID:AA0085 The formation of a C-terminal peptidyl-cysteine amide by hydrolysis and oxidation of an interior Cys-Gly peptide in a secreted protein. GO:0033652 host cell chloroplast biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033652 A chlorophyll-containing plastid as found within host cells with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0018037 C-terminal peptidyl-aspartic acid amidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018037 RESID:AA0084 The formation of a C-terminal peptidyl-aspartic acid 1-amide by hydrolysis and oxidation of an interior Asp-Gly peptide in a secreted protein. GO:0018032 protein amidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018032 protein amino acid amidation Addition of an amide group from a glycine to a protein amino acid. GO:0033651 host cell plastid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033651 Any member of a family of organelles as found in the cytoplasm of host cells, which are membrane-bounded and contain DNA. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0018031 peptidyl-lysine N6-palmitoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0018031 EC:2.3.1.- Catalysis of the transfer of a palmitoyl group to the N6 nitrogen atom on a lysine residue of a peptide or protein molecule. GO:0033650 host cell mitochondrion biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0033650 host mitochondria A semiautonomous, self replicating organelle as found in host cells that occurs in varying numbers, shapes, and sizes in the cell cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:58269 2-amino-2-deoxy-D-gluconic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_58269 GO:0018034 C-terminal peptidyl-alanine amidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018034 RESID:AA0081 The formation of a C-terminal peptidyl-alanine amide by hydrolysis and oxidation of an interior Ala-Gly peptide in a secreted protein. CHEBI:73883 UDP-alpha-D-apiose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73883 GO:0018033 protein C-terminal amidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0018033 The formation of a C-terminal amide by hydrolysis and oxidation of an interior peptide in a secreted protein. CHEBI:24803 indole-3-acetic acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24803 CHEBI:24809 indole-3-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24809 CHEBI:24810 indol-3-yl carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24810 CHEBI:24814 indole-3-methanol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_24814 CHEBI:24813 3-(indol-3-yl)lactic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24813 UBERON:0015482 right hepatic artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015482 right branch of hepatic artery proper|ramus dexter (arteria hepatica propria)|right part of hepatic artery proper A hepatic artery that is part of a right lobe of liver. UBERON:0015485 choledocho-duodenal junction biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015485 choledochoduodenal junction hat part of the duodenal wall traversed by the ductus choledochus, ductus pancreaticus, and ampulla. UBERON:0015481 left hepatic artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015481 ramus sinister (arteria hepatica propria)|left part of hepatic artery proper|left branch of hepatic artery A hepatic artery that is part of a left lobe of liver. CHEBI:2424 acetylpyruvic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_2424 CHEBI:73801 Gly-Glu biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73801 CHEBI:73803 Ala-Asp biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_73803 CHEBI:73802 1-nitrocyclohexene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_73802 GO:0008608 attachment of spindle microtubules to kinetochore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008608 kinetochore-microtubule interaction|microtubule and chromosome interaction|amphotelic attachment|spindle-chromosome interaction|attachment of spindle microtubules to chromosome|bipolar attachment|spindle chromosome attachment|kinetochore microtubule interaction|kinetochore-microtubule attachment|microtubule and kinetochore interaction|microtubule anchoring at kinetochore|microtubule capture|spindle kinetochore attachment The process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex. GO:0008607 phosphorylase kinase regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008607 EC:2.7.1.- phosphorylase kinase, intrinsic regulator activity Modulation of the activity of the enzyme phosphorylase kinase. CHEBI:48851 methoxynaphthalene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48851 GO:0008606 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008606 CHEBI:48854 sulfurous acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48854 GO:0008605 obsolete protein kinase CK2 regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008605 protein kinase CK2, intrinsic regulator activity|protein kinase CK2 regulator activity|casein kinase II, regulator OBSOLETE. Modulation of the activity of the enzyme protein kinase CK2. GO:0008604 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008604 GO:0008603 cAMP-dependent protein kinase regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008603 cAMP-dependent protein kinase, intrinsic regulator activity|3',5'-cAMP-dependent protein kinase regulator activity|adenosine 3',5'-cyclophosphate-dependent protein kinase regulator activity|cyclic AMP-dependent protein kinase regulator activity|3',5' cAMP-dependent protein kinase regulator activity Modulation of the activity of the enzyme cAMP-dependent protein kinase. CHEBI:48855 sulfino group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48855 GO:0008602 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008602 GO:0008601 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008601 GO:0008600 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0008600 CHEBI:48850 alkyloxynaphthalene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48850 CHEBI:83172 N-tetracosenoylsphingosine-1-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83172 CHEBI:83171 (2E,4Z)-2-hydroxy-7-methyl-6-oxo-2,4-octadienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83171 CHEBI:83170 (3R)-3-amino-3-phenylpropanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83170 GO:0008609 alkylglycerone-phosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008609 EC:2.5.1.26|MetaCyc:ALKYLGLYCERONE-PHOSPHATE-SYNTHASE-RXN|RHEA:36171|Reactome:R-HSA-390427 alkyldihydroxyacetonephosphate synthase activity|1-acyl-glycerone-3-phosphate:long-chain-alcohol O-3-phospho-2-oxopropanyltransferase activity|alkyl-DHAP|DHAP-AT|alkyl DHAP synthetase activity|alkyl-DHAP synthase activity|dihydroxyacetone-phosphate acyltransferase activity|alkyldihydroxyacetone phosphate synthetase activity Catalysis of the reaction: 1-acyl-glycerone 3-phosphate + a long-chain alcohol = 1-alkyl-glycerone 3-phosphate + a long-chain acid anion. GO:0008619 obsolete RHEB small monomeric GTPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008619 RHEB small monomeric GTPase activity OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. GO:0008618 7-methylguanosine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008618 7-methylguanosine metabolism The chemical reactions and pathways involving 7-methylguanosine, a modified nucleoside that forms a cap at the 5'-terminus of eukaryotic mRNA. GO:0008617 guanosine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008617 guanosine metabolism The chemical reactions and pathways involving guanine, guanine riboside, a nucleoside with a wide species distribution. GO:0008616 queuosine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008616 queuosine biosynthesis|queuosine anabolism|queuosine synthesis|queuosine formation The chemical reactions and pathways resulting in the formation of queuosines, any of a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents. GO:0008615 pyridoxine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008615 pyridoxine formation|pyridoxine biosynthesis|pyridoxine anabolism|pyridoxine synthesis The chemical reactions and pathways resulting in the formation of pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, one of the vitamin B6 compounds. GO:0008614 pyridoxine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008614 pyridoxine metabolism The chemical reactions and pathways involving pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate. CHEBI:24899 isoleucine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24899 GO:0008613 diuretic hormone activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0008613 The action characteristic of a diuretic hormone, any peptide hormone that, upon receptor binding, regulates water balance and fluid secretion. CHEBI:24898 isoleucine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24898 CHEBI:48847 heterocyclic fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_48847 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008612 RESID:AA0116 hypusine biosynthetic process from peptidyl-lysine|hypusinylation|hypusine anabolism|hypusine synthesis|hypusine formation from peptidyl-lysine|hypusine formation|hypusine synthesis from peptidyl-lysine|protein hypusination|hypusine anabolism from peptidyl-lysine|hypusine biosynthetic process|hypusine biosynthesis The modification of peptidyl-lysine to form hypusine, peptidyl-N6-(4-amino-2-hydroxybutyl)-L-lysine. CHEBI:24897 isoindoles biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24897 GO:0008611 ether lipid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008611 ether lipid biosynthesis|ether lipid anabolism|ether lipid synthesis|plasmalogen biosynthetic process|ether lipid formation The chemical reactions and pathways resulting in the formation of ether lipids, lipids that contain (normally) one lipid alcohol in ether linkage to one of the carbon atoms (normally C-1) of glycerol. GO:0008610 lipid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0008610 lipid synthesis|lipid formation|lipid biosynthesis|lipid anabolism|lipogenesis The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. UBERON:0015420 ureteral valve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015420 valve or ureter|ureteral valve A valve that is part of a ureter. CHEBI:83189 phosphatidylinositol monophosphate(3-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83189 CHEBI:10221 alpha-copaene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_10221 UBERON:0015418 urethra mesenchymal layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015418 A mesenchyme that is part of a urethra. CHEBI:2468 secondary alpha-hydroxy ketone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_2468 CHEBI:10223 alpha-cryptoxanthin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_10223 CHEBI:48848 erythronolide A biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48848 CHEBI:24863 iodophenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24863 CHEBI:24862 iodoamino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24862 CHEBI:24860 iodine molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24860 CHEBI:24867 monoatomic ion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24867 CHEBI:24866 salt biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24866 CHEBI:24865 iodotyrosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24865 CHEBI:24864 iodothyronine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24864 UBERON:0015410 heart plus pericardium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015410 heart/pericardium CHEBI:83195 glycerophosphoglycerophosphate anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83195 CHEBI:83193 phosphatidylinositol trisphosphate(7-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_83193 CHEBI:83191 phosphatidylinositol bisphosphate(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_83191 CHEBI:24869 ionophore biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24869 CHEBI:24868 organic salt biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24868 CHEBI:24874 iron ionophore biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24874 CHEBI:24873 iron molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24873 CHEBI:24875 iron cation biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_24875 CHEBI:24870 ion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24870 CHEBI:2448 actinorhodin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_2448 CHEBI:48828 cobalt(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48828 UBERON:0015474 axilla skin biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015474 skin of axilla|axillary skin A zone of skin that is part of a axilla. CHEBI:24844 inosines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24844 CHEBI:24843 inosine phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24843 OBO:GOCHE_50427 substance with platelet aggregation inhibitor role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_50427 UBERON:0015476 nose skin biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015476 external nasal skin|skin of external nose|skin of nose A zone of skin that is part of a external nose. UBERON:0015477 axillary fat pad biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015477 A fat pad that is part of a axilla. CHEBI:2490 6-oxohexanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_2490 CHEBI:24848 inositol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_24848 CHEBI:24846 inositol phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24846 CHEBI:48819 cyano group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_48819 CHEBI:2495 adrenosterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_2495 CHEBI:24852 insecticide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24852 CHEBI:24850 insect attractant biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24850 CHEBI:24853 intercalator biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24853 CHEBI:24859 iodine atom biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_24859 CHEBI:24823 indoleacetaldehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24823 CHEBI:24821 indolyl carbohydrate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24821 UBERON:0015458 mediastinal fat pad biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015458 A fat pad that is part of a mediastinum. CHEBI:10216 cedr-8-ene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_10216 UBERON:0015454 pancreatic fat pad biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015454 A fat pad that is part of a pancreas. UBERON:0015453 subcutaneous lymph node biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0015453 A lymph node that is part of a hypodermis. CHEBI:2479 adenosylcobinamide guanosyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_2479 CHEBI:10213 alpha-amyrin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_10213 CHEBI:24829 indolones biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24829 CHEBI:24828 indoles biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24828 CHEBI:24834 inorganic anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24834 CHEBI:24833 oxoacid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24833 CHEBI:24838 inorganic phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24838 CHEBI:24837 inorganic peroxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24837 CHEBI:2481 adenosylcobinamide phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_2481 CHEBI:24836 inorganic oxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24836 CHEBI:2480 adenosylcobinamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_2480 CHEBI:24835 inorganic molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24835 CHEBI:2483 adenosylcobyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_2483 CHEBI:2482 adenosylcob(III)yrinic acid a,c-diamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_2482 CHEBI:24839 inorganic salt biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_24839 UBERON:0022248 cerebral nerve fasciculus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0022248 telencephalic nerve fascicle|cerebral fascicle|nerve fascicle of telencephalon|cerebral fasciculus|telencephalic fascicle CHEBI:25214 metal-sulfur cluster biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25214 CHEBI:25213 metal cation biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_25213 CHEBI:25212 metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25212 CHEBI:25219 methacrylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25219 CHEBI:25218 methacrylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_25218 CHEBI:25216 metalloporphyrin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25216 CHEBI:15889 sterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15889 CHEBI:15888 5-oxohexanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15888 CHEBI:15885 L-2-amino-4-chloropent-4-enoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15885 CHEBI:15884 tropine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15884 CHEBI:15887 5-aminopentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15887 CHEBI:15886 UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15886 CHEBI:15881 2-oxopropyl-CoM biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15881 CHEBI:15880 S-methyl 3-phospho-1-thio-D-glycerate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15880 UBERON:0022254 ventral thalamic fasciculus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0022254 campus foreli (pars dorsalis)|tegmental area h1|forelli campus I|fasciculus thalamicus hypothalami|thalamic fasciculus|area subthalamica tegmentalis, pars dorsomedialis|forel's field h1|area tegmentalis H1|fasciculus thalamicus [h1]|field H1|h1 bundle of Forel|fasciculus thalamicus|area tegmentalis, pars dorsalis (Forel)|area tegmentalis, pars dorsalis|h1 field of Forel|thalamic fasciculus [h1] The thalamic fasciculus is a component of the subthalamus. It is sometimes considered synonymous with 'field H1 of Forel'. Nerve fibres forming a composite bundle containing cerebellothalamic (crossed) and pallidothalamic (uncrossed) fibres that is insinuated between the thalamus and zona incerta. The thalamic fasciculus consists of the joint fibers of the ansa lenticularis and the lenticular fasciculus, coming from different portions of the medial globus pallidus, before they jointly enter the ventral lateral nucleus of the thalamus. CHEBI:15883 P(1),P(4)-bis(5'-guanosyl) tetraphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15883 CHEBI:15882 phenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15882 CHEBI:25224 methanesulfonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_25224 CHEBI:25223 methanesulfonate ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_25223 CHEBI:15878 10-hydroxydihydrosanguinarine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15878 CHEBI:64834 menaquinol-7 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64834 CHEBI:15877 L-lupinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15877 CHEBI:64833 6-kestotriose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64833 CHEBI:15874 N(2)-malonyl-D-tryptophan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15874 CHEBI:64838 1D-myo-inositol 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64838 CHEBI:64837 N(pros)-phosphonato-L-histidine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64837 CHEBI:15873 alpha-D-glucosamine 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15873 CHEBI:64836 6,6-kestotetraose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64836 CHEBI:64835 1,6-kestotetraose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64835 CHEBI:15870 betaine aldehyde hydrate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15870 CHEBI:15871 o-orsellinate depside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15871 CHEBI:64839 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64839 CHEBI:64841 1D-myo-inositol 6-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64841 CHEBI:64840 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64840 UBERON:2000542 medial column biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_2000542 CHEBI:64845 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64845 CHEBI:64844 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64844 CHEBI:64849 glycyl-AMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64849 CHEBI:64848 N-acetyl-beta-muramate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64848 CHEBI:64847 L-threonyl-AMP(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64847 CHEBI:64846 glycyl-AMP(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64846 UBERON:0022279 strand of hair on external ear biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0022279 hair of tragus|hair of external ear|tragus hair OBO:cl#has_high_plasma_membrane_amount has_high_plasma_membrane_amount biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/cl#has_high_plasma_membrane_amount has_high_plasma_membrane_amount A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617). CHEBI:64851 L-threonyl-AMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64851 CHEBI:64850 N-carbamoylaspartic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64850 CHEBI:64856 N(epsilon)-GMP-N(alpha)-acetyl-L-lysine methyl ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64856 CHEBI:40822 aldehydo-D-allose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_40822 CHEBI:15899 (R)-5-diphosphomevalonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15899 CHEBI:64854 N(alpha)-acetyl-L-lysine methyl ester(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64854 UBERON:2000523 inferior reticular formation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_2000523 CHEBI:64853 N(epsilon)-(5'-guanylyl)-N(alpha)-acetyl-L-lysine methyl ester(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64853 CHEBI:15896 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15896 CHEBI:15895 D-galactono-1,4-lactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15895 CHEBI:64859 N(alpha)-acetyl-L-lysine methyl ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64859 CHEBI:64858 aminopropylcadaverine(3+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64858 CHEBI:15897 N-(long-chain-acyl)ethanolamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15897 UBERON:0022282 secretion of Harderian gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0022282 Harderian gland fluid|Harderian gland secretion A merocrine secretion that is produced by a Harderian gland, containing lipids CHEBI:64857 cosmetic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64857 CHEBI:15892 S-succinylglutathione biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15892 CHEBI:15891 taurine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15891 UBERON:0022284 lacrimal gland bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0022284 the single bud-like invagination of the conjunctival fornix epithelium at the temporal aspect of the eye that signals lacrimal gland formation (Int Rev Cytol. 1996;168:1-80. Cell biology of the harderian gland) CHEBI:15894 (2-trans,6-trans)-farnesal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15894 UBERON:0022287 tear film biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0022287 precorneal film An aqueous substance that covers the anterior surface of the eyeball, keeping the cornea wet. CHEBI:15893 1-pyrroline-5-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15893 UBERON:0022286 secretion of nictitans gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0022286 nictitans gland secretion|nictitans gland fluid A secretion that is produced by a nictitans gland, containing glycoprotein UBERON:0022288 surface of eyeball biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0022288 surface of region of wall of eyeball CHEBI:15890 5,6-dimethylbenzimidazole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15890 CHEBI:15849 aryl(methyl)malonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15849 CHEBI:64863 1-acyl-2-tetradecanoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64863 CHEBI:15848 dTDP-galactose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15848 CHEBI:64862 1-acyl-2-hexadecanoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64862 CHEBI:64861 1-acyl-2-octadecanoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64861 CHEBI:64860 aminopropylcadaverine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64860 CHEBI:15845 keto-L-tagatose 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15845 CHEBI:15844 1D-myo-inositol 3,4,5,6-tetrakisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15844 CHEBI:64865 1-acyl-2-dodecanoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64865 CHEBI:15847 2-(alpha-D-mannosyl)-D-glyceric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15847 CHEBI:15846 NAD(+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15846 CHEBI:40813 4-methoxybenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_40813 CHEBI:64864 1-acyl-2-octadecanoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64864 CHEBI:15841 polypeptide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15841 CHEBI:15840 N-acylneuraminic acid 9-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15840 CHEBI:64869 1-acyl-2-hexadecanoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64869 CHEBI:15843 arachidonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15843 CHEBI:15842 orotidine 5'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15842 CHEBI:64868 hexacosanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64868 CHEBI:64870 (S)-malyl N-acetyl-alpha-D-glucosaminide(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64870 CHEBI:64874 1-acyl-2-hexadecanoyl-sn-glycero-3-phospho-1D-myo-inositol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64874 CHEBI:15838 (7R)-7-(5-carboxy-5-oxopentanamido)cephalosporanic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15838 CHEBI:64873 1-acyl-2-tetradecanoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64873 CHEBI:15837 isoamylol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15837 CHEBI:64872 2-acyl-sn-glycero-3-phospho-1D-myo-inositol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64872 CHEBI:64871 (S)-malyl alpha-D-glucosaminide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64871 CHEBI:15834 1-O-galloyl-beta-D-glucose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15834 CHEBI:88823 14R,15S-EpETrE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88823 CHEBI:15833 sulcatol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15833 CHEBI:64877 1-acyl-2-dodecanoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64877 CHEBI:64876 bacillithiol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64876 CHEBI:15836 4-phospho-L-aspartic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15836 CHEBI:88824 N-acetylcadaverine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88824 CHEBI:64875 1-hexadecanoyl-2-acyl-sn-glycero-3-phospho-1D-myo-inositol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64875 CHEBI:15835 1-acylglycerone 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15835 CHEBI:15830 8-amino-7-oxononanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15830 CHEBI:15832 urea-1-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15832 CHEBI:15831 geranylgeranyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15831 CHEBI:64885 C20 phytosphingosine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64885 CHEBI:64884 C20 phytosphingosine 1-phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64884 CHEBI:64883 diacetylchitobiose-6'-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64883 CHEBI:64882 (S)-malyl N-acetyl-alpha-D-glucosaminide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64882 CHEBI:15867 D-xylono-1,5-lactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15867 CHEBI:64889 1-acyl-2-hexadecanoyl-sn-glycero-3-phospho-1D-myo-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64889 CHEBI:15866 2-deoxy-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15866 CHEBI:64888 (S)-malyl alpha-D-glucosaminide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64888 CHEBI:64887 C20 sphinganine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64887 CHEBI:15868 CDP-N-methylethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15868 CHEBI:64886 C20 sphinganine 1-phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64886 CHEBI:15862 ethylamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15862 CHEBI:15865 6-phospho-2-dehydro-D-gluconate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15865 CHEBI:15864 luteolin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15864 CHEBI:15861 trichodiene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15861 CHEBI:15860 N-methylhexanamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15860 UBERON:0022236 peduncle of thalamus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0022236 thalamic peduncle UBERON:0022235 peduncle of diencephalon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0022235 diencephalon peduncle CHEBI:74215 2-hydroxytetracosenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74215 CHEBI:74214 N-acetyl-alpha-D-galactosaminyl-1-diphospho-ditrans,polycis-undecaprenol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74214 NCBITaxon:2698737 Sar organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_2698737 SAR supergroup CHEBI:74216 N-(2-hydroxytetracosenoyl)sphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74216 CHEBI:74218 N-acetyl-alpha-D-galactosaminyl-1-diphospho-ditrans,polycis-undecaprenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74218 CHEBI:64891 O-(pantetheine-4'-phosphoryl)serine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64891 CHEBI:64890 1-hexadecanoyl-2-acyl-sn-glycero-3-phospho-1D-myo-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64890 CHEBI:64896 O-(pantetheine-4'-phosphoryl)serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64896 CHEBI:15859 N-carbamoyl-L-aspartic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15859 CHEBI:64894 [(1S)-4-hydroxy-2,2,3-trimethylcyclopent-3-enyl]acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64894 CHEBI:64893 bornane-2,6-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64893 CHEBI:64899 [(1S)-4-hydroxy-2,2,3-trimethylcyclopent-3-enyl]acetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64899 CHEBI:15855 UDP-6-sulfoquinovose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15855 CHEBI:64898 anionic amino-acid residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64898 CHEBI:15858 bromide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15858 CHEBI:15857 5-L-glutamyl amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15857 CHEBI:64897 diacetylchitobiose-6'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64897 CHEBI:15852 aquacob(III)alamin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15852 CHEBI:15851 3-(uracil-1-yl)-L-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15851 CHEBI:15854 quinine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15854 CHEBI:15850 1-O-alkyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15850 UBERON:0022247 forebrain ipsilateral fiber tracts biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0022247 FIFT CHEBI:74213 EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74213 CHEBI:74212 O-ureido-D-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74212 GO:0003953 NAD+ nucleosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003953 Reactome:R-HSA-8938076|Reactome:R-HSA-8870346|RHEA:16301 NAD nucleosidase activity Catalysis of the reaction: NAD+ + H2O = nicotinamide + ADP-ribose. CHEBI:50259 beta-L-allofuranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50259 GO:0003952 NAD+ synthase (glutamine-hydrolyzing) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003952 Reactome:R-HSA-197271|EC:6.3.5.1|MetaCyc:NAD-SYNTH-GLN-RXN|RHEA:24384|Wikipedia:NAD+_synthase_(glutamine-hydrolysing) NAD+ synthetase (glutamine-hydrolyzing)|deamido-NAD+:L-glutamine amido-ligase (AMP-forming)|NAD(+) synthetase (glutamine-hydrolyzing) activity|desamidonicotinamide adenine dinucleotide amidotransferase activity|DPN synthetase activity|NAD+ synthase (glutamine-hydrolysing)|NAD synthase (glutamine-hydrolyzing) activity|nicotinamide adenine dinucleotide synthetase (glutamine) activity|NAD synthetase (glutamine-hydrolysing) Catalysis of the reaction: ATP + deamido-NAD+ + L-glutamine + H2O = AMP + diphosphate + NAD+ + L-glutamate. CHEBI:49269 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49269 GO:0003955 NAD(P)H dehydrogenase (quinone) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003955 MetaCyc:NQOR-RXN|UM-BBD_reactionID:r0227|EC:1.6.5.2 NAD(P)H:quinone oxidoreductase activity|DT-diaphorase activity|NAD(P)H dehydrogenase activity|NAD(P)H-quinone dehydrogenase activity|quinone reductase activity|NAD(P)H:(quinone-acceptor)oxidoreductase activity|Naphthoquinone reductase activity|NAD(P)H: menadione oxidoreductase activity|diaphorase activity|phylloquinone reductase activity|vitamin-K reductase activity|reduced nicotinamide-adenine dinucleotide (phosphate) dehydrogenase activity|reduced NAD(P)H dehydrogenase activity|QR1|dehydrogenase, reduced nicotinamide adenine dinucleotide (phosphate, quinone) activity|viologen accepting pyridine nucleotide oxidoreductase activity|menadione reductase activity|naphthoquinone reductase activity|NAD(P)H-quinone oxidoreductase activity|NAD(P)H(2) dehydrogenase (quinone) activity|p-benzoquinone reductase activity|azoreductase activity|NAD(P)H2 dehydrogenase (quinone)|vitamin K reductase activity|NAD(P)H menadione reductase activity|menadione oxidoreductase activity|NADH-menadione reductase activity|NQO1|flavoprotein NAD(P)H-quinone reductase activity Catalysis of the reaction: NAD(P)H + H+ + a quinone = NAD(P)+ + a hydroquinone. CHEBI:50257 L-allofuranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50257 GO:0003954 NADH dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003954 EC:1.6.99.3|RHEA:11356|MetaCyc:NADH-DEHYDROGENASE-RXN NADH hydrogenase activity|diphosphopyridine diaphorase activity|cytochrome c reductase activity|NADH2 dehydrogenase activity|beta-NADH dehydrogenase dinucleotide activity|type I dehydrogenase activity|DPNH diaphorase activity|dihydrocodehydrogenase I dehydrogenase activity|NADH:cytochrome c oxidoreductase activity|NADH:(acceptor) oxidoreductase activity|diphosphopyrinase activity|NADH oxidoreductase activity|dihydronicotinamide adenine dinucleotide dehydrogenase activity|reduced diphosphopyridine nucleotide diaphorase activity|type 1 dehydrogenase activity|diaphorase activity|NADH:acceptor oxidoreductase activity|NADH diaphorase activity|NADH-menadione oxidoreductase activity Catalysis of the reaction: NADH + H+ + acceptor = NAD+ + reduced acceptor. CHEBI:50256 beta-D-allofuranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50256 GO:0003951 NAD+ kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003951 Reactome:R-HSA-197198|KEGG_REACTION:R00104|RHEA:18629|EC:2.7.1.23|Reactome:R-HSA-8955030|MetaCyc:NAD-KIN-RXN NADK|nicotinamide adenine dinucleotide kinase (phosphorylating)|ATP:NAD+ 2'-phosphotransferase activity|DPN kinase activity|nicotinamide adenine dinucleotide kinase activity|NAD kinase activity Catalysis of the reaction: ATP + NAD(+) = ADP + 2 H(+) + NADP(+). GO:0003950 NAD+ ADP-ribosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003950 Reactome:R-HSA-2187325|Reactome:R-HSA-9694773|Reactome:R-HSA-8938073|EC:2.4.2.30|Reactome:R-HSA-5651723|Reactome:R-HSA-5687653|Reactome:R-HSA-5688276|Reactome:R-HSA-8948800|Reactome:R-HSA-9686061|MetaCyc:NAD+-ADP-RIBOSYLTRANSFERASE-RXN|Reactome:R-HSA-3640858 NAD ADP-ribosyltransferase activity|ADP-ribosyltransferase (polymerizing) activity|poly(ADP-ribose)polymerase activity|poly(ADP-ribose) synthase activity|poly(adenosine diphosphate ribose) polymerase activity|poly(ADP-ribose) synthetase activity|NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity Catalysis of the reaction: NAD+ + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor. CHEBI:49262 cyclohexa-1,5-diene-1-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49262 CHEBI:49261 3-hydroxycyclohexa-1,5-diene-1-carbonyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49261 GO:1904679 myo-inositol import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904679 myo-inositol import into cell The directed movement of myo-inositol from outside of a cell, across the plasma membrane and into the cytosol. CHEBI:49264 nonatrienedicarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49264 GO:1904678 alpha-aminoacyl-tRNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1904678 aminoacyl-tRNA binding Interacting selectively and non-covalently with alpha-aminoacyl-tRNA. CHEBI:49263 (S)-beta-bisabolene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49263 GO:1904677 positive regulation of somatic stem cell division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904677 upregulation of somatic stem cell renewal|up-regulation of somatic stem cell division|activation of somatic stem cell division|up regulation of somatic stem cell renewal|positive regulation of somatic stem cell renewal|activation of somatic stem cell renewal|up regulation of somatic stem cell division|up-regulation of somatic stem cell renewal|upregulation of somatic stem cell division Any process that activates or increases the frequency, rate or extent of somatic stem cell division. CHEBI:49266 (R)-beta-bisabolene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49266 GO:1904676 negative regulation of somatic stem cell division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904676 down regulation of somatic stem cell renewal|downregulation of somatic stem cell renewal|down-regulation of somatic stem cell division|down-regulation of somatic stem cell renewal|negative regulation of somatic stem cell renewal|downregulation of somatic stem cell division|inhibition of somatic stem cell renewal|down regulation of somatic stem cell division|inhibition of somatic stem cell division Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell division. CHEBI:49265 8-[(1R,2R)-3-oxo-2-{(Z)-pent-2-en-1-yl}cyclopentyl]octanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49265 GO:1904675 regulation of somatic stem cell division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904675 regulation of somatic stem cell renewal Any process that modulates the frequency, rate or extent of somatic stem cell division. CHEBI:25297 methylenetetrahydrofolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25297 CHEBI:49268 5-amino-2-oxopentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49268 GO:1904674 positive regulation of somatic stem cell population maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904674 up regulation of somatic stem cell population maintenance|upregulation of somatic stem cell population maintenance|activation of somatic stem cell population maintenance|up-regulation of somatic stem cell population maintenance Any process that activates or increases the frequency, rate or extent of somatic stem cell population maintenance. GO:1904684 negative regulation of metalloendopeptidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904684 inhibition of metalloendoprotease activity|inhibition of metalloendopeptidase activity|down-regulation of metalloendoproteinase activity|negative regulation of metalloendoproteinase activity|down-regulation of metalloendoprotease activity|down regulation of metalloendopeptidase activity|downregulation of metalloendoproteinase activity|negative regulation of metalloendoprotease activity|downregulation of metalloendopeptidase activity|down regulation of metalloendoproteinase activity|downregulation of metalloendoprotease activity|down regulation of metalloendoprotease activity|inhibition of metalloendoproteinase activity|down-regulation of metalloendopeptidase activity Any process that stops, prevents or reduces the frequency, rate or extent of metalloendopeptidase activity. GO:1904683 regulation of metalloendopeptidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904683 regulation of metalloendoproteinase activity|regulation of metalloendoprotease activity Any process that modulates the frequency, rate or extent of metalloendopeptidase activity. GO:1904682 cellular response to 3-methylcholanthrene biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904682 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3-methylcholanthrene stimulus. GO:1904681 response to 3-methylcholanthrene biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904681 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3-methylcholanthrene stimulus. GO:1904680 peptide transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1904680 Reactome:R-HSA-1500817 peptide uptake permease activity|peptide transporter activity Enables the transfer of a peptide from one side of a membrane to the other. CHEBI:49271 (5xi,7xi,10xi)-eudesma-4(14),11-diene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49271 CHEBI:49270 12alpha-hydroxy-3-oxochola-4,6-dien-24-oic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49270 CHEBI:50250 (4R,7S)-7-isopropyl-4-methyloxepan-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50250 GO:0003957 NAD(P)+ transhydrogenase (B-specific) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003957 MetaCyc:PYRNUTRANSHYDROGEN-RXN|EC:1.6.1.1 NAD transhydrogenase|pyridine nucleotide transhydrogenase activity|H+-thase|NADH transhydrogenase|nicotinamide nucleotide transhydrogenase activity|non-energy-linked transhydrogenase activity|NADPH-NAD oxidoreductase|nicotinamide adenine dinucleotide (phosphate) transhydrogenase|NADH-NADP-transhydrogenase|NAD(P) transhydrogenase (B-specific) activity|NADPH:NAD+ oxidoreductase (B-specific)|NADPH:NAD+ transhydrogenase|NADPH-NAD transhydrogenase|pyridine nucleotide transferase Catalysis of the reaction: NADPH + H+ + NAD+ = NADP+ + NADH + H+, driving the transfer of a solute or solutes from one side of a membrane to the other. In the course of the reaction (left to right) one H atom is transferred from inside the cell to outside. The reaction is B-specific (i.e. the pro-S hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to both NAD+ and NADP+. GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003956 EC:2.4.2.31|Reactome:R-HSA-1972385|MetaCyc:2.4.2.31-RXN protein-arginine ADP-ribosyltransferase activity|mono(ADPribosyl)transferase activity|NAD(P)+:protein-L-arginine ADP-D-ribosyltransferase activity|mono(ADP-ribosyl)transferase activity|NAD(+):L-arginine ADP-D-ribosyltransferase activity|NAD(P)-arginine ADP-ribosyltransferase activity|peptidyl-arginine ADP-ribosylation activity|NAD+:L-arginine ADP-D-ribosyltransferase activity|NAD(P)+:L-arginine ADP-D-ribosyltransferase activity|NAD(P)(+)--arginine ADP-ribosyltransferase activity|ADP-ribosyltransferase activity|NAD(P)+-arginine ADP-ribosyltransferase activity Catalysis of the reaction: NAD(P)+ + L-arginine = nicotinamide + N2-(ADP-D-ribosyl)-L-arginine. CHEBI:50254 D-allofuranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50254 GO:0003959 NADPH dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003959 UM-BBD_enzymeID:e0523|MetaCyc:NADPH-DEHYDROGENASE-RXN|EC:1.6.99.1|Reactome:R-HSA-9018901|Reactome:R-HSA-9018867|Reactome:R-HSA-9027632|Reactome:R-HSA-9027625|Reactome:R-HSA-9027631 NADPH:(acceptor) oxidoreductase activity|NADPH-dehydrogenase activity|NADPH2-dehydrogenase activity|triphosphopyridine diaphorase activity|TPNH-diaphorase activity|NADPH2 diaphorase activity|NADPH diaphorase activity|OYE|NADPH:acceptor oxidoreductase activity|triphosphopyridine nucleotide diaphorase activity|dihydronicotinamide adenine dinucleotide phosphate dehydrogenase activity|old yellow enzyme|reduced nicotinamide adenine dinucleotide phosphate dehydrogenase activity|TPNH dehydrogenase activity Catalysis of the reaction: NADPH + H+ + acceptor = NADP+ + reduced acceptor. CHEBI:50253 allofuranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50253 GO:0003958 NADPH-hemoprotein reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003958 Reactome:R-HSA-76494|MetaCyc:NADPH--FERRIHEMOPROTEIN-REDUCTASE-RXN|EC:1.6.2.4|RHEA:24040 NADPH--ferrihemoprotein reductase activity|TPNH-cytochrome c reductase activity|TPNH(2) cytochrome c reductase activity|NADPH--ferricytochrome c oxidoreductase activity|cytochrome P-450 reductase activity|POR|NADPH--cytochrome P450 oxidoreductase activity|NADP--cytochrome reductase activity|reduced nicotinamide adenine dinucleotide phosphate-cytochrome c reductase activity|NADPH-cytochrome p-450 reductase activity|NADPH--cytochrome P450 reductase activity|NADPH:P-450 reductase activity|NADPH:hemoprotein oxidoreductase activity|NADP--cytochrome c reductase activity|NADPH-ferrihemoprotein reductase activity|NADPH:cytochrome c reductase activity|NADPH:P450 reductase activity|CPR activity|NADPH:cytochrome P450 reductase activity|NADPH-dependent cytochrome c reductase activity|cytochrome P450 reductase activity|NADPH:ferrihemoprotein oxidoreductase activity|dihydroxynicotinamide adenine dinucleotide phosphate-cytochrome c reductase activity|ferrihemoprotein P-450 reductase activity|NADPH--cytochrome c reductase activity|cytochrome c reductase (reduced nicotinamide adenine dinucleotide phosphate, NADPH, NADPH-dependent) activity|FAD-cytochrome c reductase activity|TPNH2 cytochrome c reductase activity|aldehyde reductase (NADPH-dependent) activity|NADPH--cytochrome c oxidoreductase activity|NADPH-cytochrome P-450 oxidoreductase activity|reductase, cytochrome c (reduced nicotinamide adenine dinucleotide phosphate) activity Catalysis of the reaction: NADPH + H+ + n oxidized hemoprotein = NADP+ + n reduced hemoprotein. GO:0003964 RNA-directed DNA polymerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003964 Reactome:R-HSA-164504|MetaCyc:RNA-DIRECTED-DNA-POLYMERASE-RXN|Reactome:R-HSA-164520|EC:2.7.7.49 DNA nucleotidyltransferase (RNA-directed) activity|RT|RNA-instructed DNA polymerase activity|RNA-directed DNA polymerase, group II intron encoded|revertase activity|RNA revertase activity|RNA-dependent DNA polymerase activity|RNA-dependent deoxyribonucleate nucleotidyltransferase activity|reverse transcriptase activity|RNA-directed DNA polymerase, transposon encoded|deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (RNA-directed) activity Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time. CHEBI:49259 (2S)-2-[(R)-1-carboxyethylamino]pentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49259 CHEBI:50248 hematologic agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50248 GO:0003963 RNA-3'-phosphate cyclase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003963 RHEA:23976|MetaCyc:RNA-3-PHOSPHATE-CYCLASE-RXN|EC:6.5.1.4 RNA 3'-terminal phosphate cyclase activity|RNA-3'-phosphate:RNA ligase (cyclizing, AMP-forming)|RNA cyclase activity Catalysis of the reaction: ATP + RNA 3'-terminal-phosphate = AMP + diphosphate + RNA terminal-2',3'-cyclic-phosphate. CHEBI:50247 antidote biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50247 CHEBI:49258 (2R,3R)-2,3-dihydroxy-3-methylpentanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49258 GO:0003966 obsolete RNA-directed DNA polymerase, transposon encoded biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003966 RNA-directed DNA polymerase, transposon encoded OBSOLETE. Catalysis of RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time; cannot initiate a chain de novo. CHEBI:50246 1-hydroxylimonen-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50246 CHEBI:50245 (1R,4S)-1-hydroxylimonen-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50245 GO:0003960 NADPH:quinone reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003960 Reactome:R-HSA-6799722|MetaCyc:QOR-RXN|EC:1.6.5.5|RHEA:14269 quinone oxidoreductase activity|zeta-crystallin activity|NADPH:quinone oxidoreductase activity Catalysis of the reaction: NADPH + H+ + quinone = NADP+ + semiquinone. GO:0003962 cystathionine gamma-synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003962 MetaCyc:O-SUCCHOMOSERLYASE-RXN|EC:2.5.1.48|RHEA:20397 cystathionine synthase activity|cystathionine g-synthase activity|O-succinyl-L-homoserine succinate-lyase (adding cysteine) activity|O-succinylhomoserine synthetase activity|CTT gamma synthase activity|homoserine O-transsuccinylase activity|O4-succinyl-L-homoserine:L-cysteine S-(3-amino-3-carboxypropyl)transferase activity|homoserine transsuccinylase activity|cystathionine synthetase activity|O-succinyl-L-homoserine (thiol)-lyase activity|cystathionine gamma synthase activity|O-succinylhomoserine synthase activity|O-succinylhomoserine (thiol)-lyase activity|O-succinyl-L-homoserine succinate-lyase activity Catalysis of the reaction: O-succinyl-L-homoserine + L-cysteine = cystathionine + succinate. GO:0003961 O-acetylhomoserine aminocarboxypropyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003961 MetaCyc:O-ACETYLHOMOSERINE-THIOL-LYASE-RXN|EC:2.5.1.49|RHEA:10048 L-methionine synthesis, direct, from O-acetyl-L-homoserine|O-acetylhomoserine sulfhydrolase activity|L-methionine formation, direct, from O-acetyl-L-homoserine|O-acetyl-L-homoserine:methanethiol 3-amino-3-carboxypropyltransferase activity|O-acetyl-L-homoserine sulfhydrolase activity|L-methionine biosynthetic process, direct, from O-acetyl-L-homoserine|methionine biosynthetic process, direct, from O-acetyl-L-homoserine|O-acetyl-L-homoserine acetate-lyase (adding methanethiol) activity|OAH sulfhydrylase activity|O-acetylhomoserine (thiol)-lyase activity|L-methionine anabolism, direct, from O-acetyl-L-homoserine Catalysis of the reaction: O-acetyl-L-homoserine + methanethiol = L-methionine + acetate. Also reacts with other thiols and H2S, producing homocysteine or thioethers. CHEBI:50249 anticoagulant biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50249 CHEBI:49253 (9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49253 GO:0062240 euchromatin-nuclear membrane anchor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062240 nuclear membrane-euchromatin tether activity|nuclear membrane-euchromatin anchor activity|euchromatin-nuclear membrane tether activity Interacting selectively and non-covalently with euchromatin and the nuclear inner membrane, in order to establish and maintain the euchromatin location and organization. GO:1904689 negative regulation of cytoplasmic translational initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904689 downregulation of cytoplasmic translational initiation|down regulation of cytoplasmic translational initiation|inhibition of cytoplasmic translational initiation|down-regulation of cytoplasmic translational initiation Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational initiation. CHEBI:49252 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49252 GO:1904688 regulation of cytoplasmic translational initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904688 Any process that modulates the frequency, rate or extent of cytoplasmic translational initiation. GO:0062242 double membrane vesicle viral factory membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062242 membrane of double membrane vesicle viral factory One of the two endoplasmic reticulum-derived lipid bilayer membranes that bound a double membrane vesicle viral factory. CHEBI:49255 N-(6-aminohexanoyl)-6-aminohexanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49255 GO:1904687 positive regulation of mitotic spindle disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904687 up-regulation of spindle breakdown during mitosis|up regulation of spindle disassembly during mitosis|activation of spindle breakdown during mitosis|up-regulation of mitotic spindle breakdown|up regulation of mitotic spindle disassembly|activation of mitotic spindle disassembly|upregulation of mitotic spindle catabolism|up-regulation of spindle degradation during mitosis|activation of spindle degradation during mitosis|upregulation of mitotic spindle degradation|upregulation of spindle disassembly during mitosis|positive regulation of spindle breakdown during mitosis|upregulation of mitotic spindle breakdown|up regulation of spindle breakdown during mitosis|up-regulation of mitotic spindle catabolism|up-regulation of mitotic spindle disassembly|activation of mitotic spindle catabolism|up regulation of mitotic spindle degradation|positive regulation of spindle degradation during mitosis|positive regulation of mitotic spindle degradation|up regulation of spindle degradation during mitosis|activation of mitotic spindle degradation|up-regulation of spindle disassembly during mitosis|activation of spindle disassembly during mitosis|up regulation of mitotic spindle breakdown|positive regulation of mitotic spindle breakdown|activation of mitotic spindle breakdown|upregulation of spindle breakdown during mitosis|upregulation of mitotic spindle disassembly|positive regulation of mitotic spindle catabolism|up regulation of mitotic spindle catabolism|upregulation of spindle degradation during mitosis|up-regulation of mitotic spindle degradation|positive regulation of spindle disassembly during mitosis Any process that activates or increases the frequency, rate or extent of mitotic spindle disassembly. GO:0062241 double strand break-nuclear membrane anchor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062241 DNA repair factory Interacting selectively and non-covalently with DNA double strand breaks and the nuclear inner membrane, in order to facilitate DNA repair. CHEBI:49254 (S,S)-9,10-dihydroxyoctadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49254 GO:1904686 regulation of mitotic spindle disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904686 regulation of mitotic spindle catabolism|regulation of spindle disassembly during mitosis|regulation of mitotic spindle degradation|regulation of mitotic spindle breakdown|regulation of spindle breakdown during mitosis|regulation of spindle degradation during mitosis Any process that modulates the frequency, rate or extent of mitotic spindle disassembly. GO:0062244 double membrane vesicle viral factory lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062244 lumen of double membrane vesicle viral factory The volume surrounded by the inner membrane of a double membrane vesicle viral factory. CHEBI:49257 (R)-3-hydroxy-3-methyl-2-oxopentanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49257 GO:1904685 positive regulation of metalloendopeptidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904685 upregulation of metalloendoprotease activity|up-regulation of metalloendoproteinase activity|up-regulation of metalloendopeptidase activity|up-regulation of metalloendoprotease activity|activation of metalloendoproteinase activity|positive regulation of metalloendoproteinase activity|activation of metalloendoprotease activity|upregulation of metalloendopeptidase activity|up regulation of metalloendoproteinase activity|positive regulation of metalloendoprotease activity|up regulation of metalloendoprotease activity|up regulation of metalloendopeptidase activity|activation of metalloendopeptidase activity|upregulation of metalloendoproteinase activity Any process that activates or increases the frequency, rate or extent of metalloendopeptidase activity. CHEBI:49256 (S)-2-acetyl-2-hydroxybutanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49256 GO:0062243 double membrane vesicle viral factory outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062243 outer membrane of double membrane vesicle viral factory The outer of the two endoplasmic reticulum-derived lipid bilayer membranes that bound a double membrane vesicle viral factory. GO:0062246 exocytic vesicle lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062246 The volume enclosed by an exocytic vesicle. GO:1904695 positive regulation of vascular associated smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904695 up regulation of vascular smooth muscle contraction|upregulation of vascular smooth muscle contraction|positive regulation of vascular smooth muscle contraction|up-regulation of vascular smooth muscle contraction|activation of vascular smooth muscle contraction Any process that activates or increases the frequency, rate or extent of vascular smooth muscle contraction. GO:1904694 negative regulation of vascular associated smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904694 down-regulation of vascular smooth muscle contraction|downregulation of vascular smooth muscle contraction|down regulation of vascular smooth muscle contraction|inhibition of vascular smooth muscle contraction|negative regulation of vascular smooth muscle contraction Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle contraction. GO:0062245 double membrane vesicle viral factory inner membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062245 inner membrane of double membrane vesicle viral factory The inner of the two endoplasmic reticulum-derived lipid bilayer membranes that bound a double membrane vesicle viral factory. GO:1904693 midbrain morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904693 MB morphogenesis|mesencephalon morphogenesis The developmental process by which a midbrain is generated and organized. GO:0062248 cleistothecium formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062248 The process of producing a cleistothecium, a closed sexual fruiting body that contains ascospores in linear asci. Cleistothecia are present in some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella. GO:1904692 positive regulation of type B pancreatic cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904692 up regulation of type B pancreatic cell proliferation|up regulation of pancreatic beta cell proliferation|upregulation of pancreatic B cell proliferation|upregulation of type B pancreatic cell proliferation|upregulation of pancreatic beta cell proliferation|up regulation of pancreatic B cell proliferation|activation of pancreatic B cell proliferation|positive regulation of pancreatic B cell proliferation|up-regulation of type B pancreatic cell proliferation|up-regulation of pancreatic beta cell proliferation|activation of type B pancreatic cell proliferation|activation of pancreatic beta cell proliferation|up-regulation of pancreatic B cell proliferation|positive regulation of pancreatic beta cell proliferation Any process that activates or increases the frequency, rate or extent of type B pancreatic cell proliferation. GO:0062247 chloroplast vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062247 A intracellular vesicle that is part of a chloroplast. GO:1904691 negative regulation of type B pancreatic cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904691 downregulation of pancreatic beta cell proliferation|downregulation of type B pancreatic cell proliferation|down regulation of pancreatic beta cell proliferation|down regulation of type B pancreatic cell proliferation|down regulation of pancreatic B cell proliferation|inhibition of type B pancreatic cell proliferation|inhibition of pancreatic beta cell proliferation|downregulation of pancreatic B cell proliferation|down-regulation of pancreatic B cell proliferation|negative regulation of pancreatic B cell proliferation|negative regulation of pancreatic beta cell proliferation|down-regulation of type B pancreatic cell proliferation|down-regulation of pancreatic beta cell proliferation|inhibition of pancreatic B cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell proliferation. GO:1904690 positive regulation of cytoplasmic translational initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904690 up regulation of cytoplasmic translational initiation|upregulation of cytoplasmic translational initiation|up-regulation of cytoplasmic translational initiation|activation of cytoplasmic translational initiation Any process that activates or increases the frequency, rate or extent of cytoplasmic translational initiation. CHEBI:49260 4-(L-gamma-glutamylamino)butanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49260 GO:0003968 RNA-directed 5'-3' RNA polymerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003968 EC:2.7.7.48|Reactome:R-HSA-9682465|Reactome:R-HSA-9681840|Reactome:R-HSA-168280|Reactome:R-HSA-9682563|Reactome:R-HSA-9694792|Reactome:R-HSA-192832|Reactome:R-HSA-9694605|Reactome:R-HSA-9694506|Reactome:R-HSA-9685639|Reactome:R-HSA-9694581|Reactome:R-HSA-192624|Reactome:R-HSA-192916|Reactome:R-HSA-9681674|Reactome:R-HSA-9694344|Reactome:R-HSA-9681651|Reactome:R-HSA-168301|Reactome:R-HSA-9685681|Reactome:R-HSA-9694277|MetaCyc:RNA-DIRECTED-RNA-POLYMERASE-RXN|Reactome:R-HSA-9694549|Reactome:R-HSA-192851 RNA-dependent RNA replicase activity|RNA-dependent RNA polymerase activity|RNA replicase activity|3D polymerase activity|ribonucleic replicase activity|RNA nucleotidyltransferase (RNA-directed) activity|Q-beta replicase activity|RNA-dependent ribonucleate nucleotidyltransferase activity|phage f2 replicase|ribonucleic acid-dependent ribonucleic acid polymerase activity|transcriptase|ribonucleic acid replicase activity|ribonucleic synthetase activity|PB1 proteins|RNA-directed RNA polymerase activity|polymerase L|PB2 proteins|RDRP|RNA synthetase activity|ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed) Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); uses an RNA template, i.e. the catalysis of RNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. CHEBI:50244 (1R,2R,4S)-limonene-1,2-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50244 CHEBI:50243 7-isopropyl-4-methyloxepan-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50243 GO:0003967 obsolete RNA-directed DNA polymerase, group II intron encoded biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003967 RNA-directed DNA polymerase, group II intron encoded OBSOLETE. Catalysis of RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time; cannot initiate a chain de novo. GO:0003969 obsolete RNA editase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003969 RNA editase activity OBSOLETE. (Was not defined before being made obsolete). GO:0003931 obsolete Rho small monomeric GTPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003931 Rho small monomeric GTPase activity OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. Any member of the Rho subfamily of the RAS superfamily of monomeric GTPases. Proteins in the Rho subfamily are involved in relaying signals from cell-surface receptors to the actin cytoskeleton. CHEBI:49248 ionone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49248 GO:0003930 obsolete RAS small monomeric GTPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003930 RAS small monomeric GTPase activity OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. CHEBI:49247 apo carotenoid monoterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49247 GO:0003933 GTP cyclohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003933 Catalysis of the hydrolysis of the imidazole ring of GTP, releasing formate. Two C-N bonds are hydrolyzed and the pentase unit is isomerized. CHEBI:50235 (+)-dihydrocarveol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50235 CHEBI:49249 beta-bisabolene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49249 GO:0003932 obsolete SAR small monomeric GTPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003932 SAR small monomeric GTPase activity OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. CHEBI:50239 epsilon-lactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50239 CHEBI:50238 4-isopropenyl-7-methyloxepan-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50238 CHEBI:49240 alpha-bisabolene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49240 CHEBI:25273 methyladenosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25273 CHEBI:25272 methyladenine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25272 CHEBI:49242 (E)-alpha-bisabolene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49242 CHEBI:25271 methyl-branched fatty acyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25271 CHEBI:25270 methyl myo-inositols biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25270 GO:1904699 positive regulation of acinar cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904699 upregulation of acinic cell proliferation|up regulation of acinar cell proliferation|activation of acinar cell proliferation|upregulation of acinous cell proliferation|up regulation of acinic cell proliferation|positive regulation of acinic cell proliferation|activation of acinic cell proliferation|up-regulation of acinar cell proliferation|up-regulation of acinous cell proliferation|activation of acinous cell proliferation|upregulation of acinar cell proliferation|up-regulation of acinic cell proliferation|positive regulation of acinous cell proliferation|up regulation of acinous cell proliferation Any process that activates or increases the frequency, rate or extent of acinar cell proliferation. CHEBI:49244 (E,S)-alpha-bisabolene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49244 GO:1904698 negative regulation of acinar cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904698 downregulation of acinous cell proliferation|down regulation of acinic cell proliferation|down regulation of acinous cell proliferation|inhibition of acinous cell proliferation|down-regulation of acinar cell proliferation|downregulation of acinic cell proliferation|inhibition of acinar cell proliferation|down-regulation of acinic cell proliferation|negative regulation of acinic cell proliferation|inhibition of acinic cell proliferation|down-regulation of acinous cell proliferation|negative regulation of acinous cell proliferation|down regulation of acinar cell proliferation|downregulation of acinar cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of acinar cell proliferation. CHEBI:49243 (E,R)-alpha-bisabolene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49243 GO:1904697 regulation of acinar cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904697 regulation of acinous cell proliferation|regulation of acinic cell proliferation Any process that modulates the frequency, rate or extent of acinar cell proliferation. CHEBI:25275 methylaniline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25275 GO:1904696 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1904696 CHEBI:25274 methylamines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25274 CHEBI:25280 methylbenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25280 GO:0003939 L-iditol 2-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003939 Reactome:R-HSA-5652195|MetaCyc:L-IDITOL-2-DEHYDROGENASE-RXN|EC:1.1.1.14|RHEA:10160 sorbitol dehydrogenase activity|glucitol dehydrogenase activity|NAD-sorbitol dehydrogenase|L-iditol:NAD oxidoreductase activity|NAD+-dependent sorbitol dehydrogenase activity|L-iditol:NAD+ 5-oxidoreductase activity|L-iditol (sorbitol) dehydrogenase activity|polyol dehydrogenase activity|NAD-dependent sorbitol dehydrogenase activity Catalysis of the reaction: L-iditol + NAD+ = L-sorbose + NADH + H+. GO:0003938 IMP dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003938 Reactome:R-HSA-73794|RHEA:11708|MetaCyc:IMP-DEHYDROG-RXN|EC:1.1.1.205 inosinate dehydrogenase activity|inosine 5'-monophosphate dehydrogenase activity|inosine monophosphate oxidoreductase activity|inosine monophosphate dehydrogenase activity|IMP oxidoreductase activity|inosinic acid dehydrogenase activity|IMP:NAD+ oxidoreductase activity|inosine-5'-phosphate dehydrogenase activity Catalysis of the reaction: inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH + H+. CHEBI:50233 (+)-isodihydrocarveol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50233 GO:0003935 GTP cyclohydrolase II activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003935 RHEA:23704|KEGG_REACTION:R00425|EC:3.5.4.25|MetaCyc:GTP-CYCLOHYDRO-II-RXN GTP-8-formylhydrolase activity|guanosine triphosphate cyclohydrolase II|GTP 7,8-8,9-dihydrolase (diphosphate-forming) Catalysis of the reaction: GTP + 3 H(2)O = 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + diphosphate + formate + 3 H(+). GO:0003934 GTP cyclohydrolase I activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003934 MetaCyc:GTP-CYCLOHYDRO-I-RXN|KEGG_REACTION:R00424|EC:3.5.4.16|Reactome:R-HSA-1474146|RHEA:17473 GTP 8-formylhydrolase activity|guanosine triphosphate cyclohydrolase activity|guanosine triphosphate 8-deformylase activity|GTP 7,8-8,9-dihydrolase activity|dihydroneopterin triphosphate synthase activity Catalysis of the reaction: GTP + H2O = formate + 7,8-dihydroneopterin 3'-triphosphate. CHEBI:50232 (+)-neoisodihydrocarveol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50232 GO:0003937 IMP cyclohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003937 MetaCyc:IMPCYCLOHYDROLASE-RXN|Reactome:R-HSA-73797|EC:3.5.4.10|RHEA:18445 IMP synthetase activity|IMP 1,2-hydrolase (decyclizing)|inosinate cyclohydrolase activity|inosinicase activity Catalysis of the reaction: IMP + H2O = 5-formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide. GO:0003936 obsolete hydrogen-transporting two-sector ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003936 proton-transporting two-sector ATPase activity|hydrogen-transporting two-sector ATPase activity OBSOLETE. Catalysis of the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out). GO:0003942 N-acetyl-gamma-glutamyl-phosphate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003942 MetaCyc:N-ACETYLGLUTPREDUCT-RXN|EC:1.2.1.38|RHEA:21588 NAGSA dehydrogenase activity|N-acetyl-L-glutamate-5-semialdehyde:NADP+ 5-oxidoreductase (phosphorylating)|N-acetyl-glutamate semialdehyde dehydrogenase activity|N-acetyl-L-glutamate gamma-semialdehyde:NADP oxidoreductase (phosphorylating)|reductase, acetyl-gamma-glutamyl phosphate|N-acetylglutamate 5-semialdehyde dehydrogenase activity|N-acetylglutamic gamma-semialdehyde dehydrogenase activity Catalysis of the reaction: N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate = N-acetyl-5-glutamyl phosphate + NADPH + H+. CHEBI:49237 gamma-bisabolene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49237 CHEBI:50226 7-methyl-GTP(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50226 GO:0003941 L-serine ammonia-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003941 MetaCyc:4.3.1.17-RXN|RHEA:19169|EC:4.3.1.17 L-serine deaminase activity|serine deaminase activity|L-serine dehydratase activity|L-hydroxyaminoacid dehydratase activity|L-serine dehydration activity|L-serine ammonia-lyase (pyruvate-forming) activity|L-serine hydro-lyase (deaminating) activity Catalysis of the reaction: L-serine = pyruvate + NH3. GO:0003944 N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003944 RHEA:24372|MetaCyc:3.1.4.45-RXN|EC:3.1.4.45 lysosomal alpha-N-acetylglucosaminidase activity|alpha-N-acetylglucosaminyl phosphodiesterase activity|alpha-N-acetyl-D-glucosamine-1-phosphodiester N-acetylglucosaminidase activity|2-acetamido-2-deoxy-alpha-D-glucose 1-phosphodiester acetamidodeoxyglucohydrolase activity|glycoprotein-N-acetyl-D-glucosaminyl-phospho-D-mannose N-acetyl-D-glucosaminylphosphohydrolase activity|phosphodiester glycosidase activity Catalysis of the reaction: glycoprotein N-acetyl-D-glucosaminyl-phospho-D-mannose + H2O = N-acetyl-D-glucosamine + glycoprotein phospho-D-mannose. CHEBI:49239 (E)-gamma-bisabolene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49239 GO:0003943 N-acetylgalactosamine-4-sulfatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003943 Reactome:R-HSA-2282889|Reactome:R-HSA-1606789|Reactome:R-HSA-1793207|Wikipedia:Arylsulfatase_B|MetaCyc:3.1.6.12-RXN|Reactome:R-HSA-9036065|EC:3.1.6.12 arylsulfatase B|N-acetyl-D-galactosamine-4-sulfate 4-sulfohydrolase activity|acetylgalactosamine 4-sulfatase activity|N-acetylgalactosamine-4-sulphatase activity|N-acetylgalactosamine 4-sulfate sulfohydrolase activity|chondroitinsulfatase Catalysis of the hydrolysis of the 4-sulfate groups of the N-acetyl-D-galactosamine 4-sulfate units of chondroitin sulfate and dermatan sulfate. CHEBI:49238 (Z)-gamma-bisabolene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49238 CHEBI:25289 methylcatechol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25289 CHEBI:50229 Schiff base biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50229 GO:0003940 L-iduronidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003940 Reactome:R-HSA-9036037|Reactome:R-HSA-1678716|Reactome:R-HSA-1793186|MetaCyc:3.2.1.76-RXN|Reactome:R-HSA-2206299|Reactome:R-HSA-9036041|Reactome:R-HSA-2090037|EC:3.2.1.76 glycosaminoglycan alpha-L-iduronohydrolase activity|alpha-L-iduronidase activity Catalysis of the hydrolysis of alpha-L-iduronosidic linkages in dermatan sulfate. CHEBI:49231 sibirene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49231 CHEBI:25282 methylbutanal biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25282 CHEBI:25281 methylbenzyl alcohol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25281 CHEBI:49235 bisabolene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49235 CHEBI:25286 methylbutanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25286 GO:0003949 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003949 RHEA:15469|KEGG_REACTION:R04640|MetaCyc:PRIBFAICARPISOM-RXN|EC:5.3.1.16 phosphoribosylformiminoaminophosphoribosylimidazolecarboxamide isomerase activity|N-(5'-phospho-D-ribosylformimino)-5-amino-1-(5''-phosphoribosyl)-4-imidazolecarboxamide isomerase activity|1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide aldose-ketose-isomerase activity|N-(phosphoribosylformimino) aminophosphoribosylimidazolecarboxamide isomerase activity|phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase activity|1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide ketol-isomerase activity Catalysis of the reaction: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide = 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. GO:0003946 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003946 GO:0003945 N-acetyllactosamine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003945 RHEA:17745|MetaCyc:N-ACETYLLACTOSAMINE-SYNTHASE-RXN|EC:2.4.1.90 UDP-galactose-N-acetylglucosamine beta-D-galactosyltransferase activity|UDP-galactose N-acetylglucosamine beta-4-galactosyltransferase activity|UDP-beta-1,4-galactosyltransferase activity|lactosamine synthase activity|NAL synthetase activity|UDP-galactose-acetylglucosamine galactosyltransferase activity|UDP-galactose-N-acetylglucosamine galactosyltransferase activity|UDPgalactose:N-acetylglucosaminyl(beta-1,4)galactosyltransferase activity|Gal-T|UDP-Gal:N-acetylglucosamine beta-1,4-galactosyltransferase activity|UDP-galactose:N-acetyl-D-glucosamine 4-beta-D-galactosyltransferase activity|beta-1,4-GalT|lactosamine synthetase activity|beta-N-acetylglucosaminide beta-1,4-galactosyltransferase activity|lactose synthetase A protein|UDP-galactose-N-acetylglucosamine beta-1,4-galactosyltransferase activity|UDPgalactose-N-acetylglucosamine beta-D-galactosyltransferase activity|beta-(1,4)-galactosyltransferase activity|beta-1,4-galactosyltransferase activity|UDPgalactose:N-acetyl-D-glucosamine 4-beta-D-galactosyltransferase activity|uridine diphosphogalactose-acetylglucosamine galactosyltransferase activity|N-acetyllactosamine synthetase activity|acetyllactosamine synthetase activity|N-acetylglucosamine beta-(1,4)-galactosyltransferase activity|N-acetylglucosamine (beta-1,4)galactosyltransferase activity|UDP-galactose:N-acetylglucosaminide beta-1,4-galactosyltransferase activity Catalysis of the reaction: UDP-galactose + N-acetyl-D-glucosamine = UDP + N-acetyllactosamine. GO:0003948 N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003948 RHEA:11544|KEGG_REACTION:R03421|MetaCyc:3.5.1.26-RXN|EC:3.5.1.26 4-N-(beta-N-acetyl-D-glucosaminyl)-L-asparagine amidohydrolase activity|glycosylasparaginase activity|aspartylglucosylaminase activity|glucosylamidase activity|aspartylglucosylaminidase activity|N-aspartyl-beta-glucosaminidase activity|aspartylglucosylamine deaspartylase activity|N4-(beta-N-acetyl-D-glucosaminyl)-L-asparagine amidohydrolase activity|aspartylglucosaminidase activity|aspartylglycosylamine amidohydrolase activity|beta-aspartylglucosylamine amidohydrolase activity Catalysis of the reaction: N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H(2)O = N-acetyl-beta-D-glucosaminylamine + L-aspartate + H(+). GO:0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003947 RHEA:12588|EC:2.4.1.92|Reactome:R-HSA-8856223|MetaCyc:2.4.1.92-RXN GalNAc-T activity|uridine diphosphoacetylgalactosamine-acetylneuraminylgalactosylglucosylceramide acetylgalactosaminyltransferase activity|asialo-GM2 synthase activity|UDP-N-acetylgalactosamine GM3 N-acetylgalactosaminyltransferase activity|GM2 synthase activity|UDP-N-acetyl-D-galactosamine:1-O-[O-(N-acetyl-alpha-neuraminosyl)-(2->3)-O-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranosyl]-ceramide 1,4-beta-N-acetyl-D-galactosaminyltransferase activity|GM2/GD2-synthase activity|ganglioside GM2 synthase activity|UDP-N-acetyl-D-galactosamine:(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide N-acetyl-D-galactosaminyltransferase activity|beta-1,4N-aetylgalactosaminyltransferase activity|uridine diphosphoacetylgalactosamine-hematoside acetylgalactosaminyltransferase activity|ganglioside GM3 acetylgalactosaminyltransferase activity|uridine diphosphoacetylgalactosamine-ganglioside GM3 acetylgalactosaminyltransferase activity|UDP acetylgalactosamine-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide acetylgalactosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + (N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide = UDP + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide. CHEBI:50215 dihydrocarveol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50215 GO:0003911 DNA ligase (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003911 MetaCyc:DNA-LIGASE-NAD+-RXN|EC:6.5.1.2 DNA-joining enzyme|deoxyribonucleic-joining enzyme|polynucleotide ligase (NAD+) activity|deoxyribonucleate ligase|DNA ligase (NAD)|polynucleotide ligase (NAD(+)) activity|deoxyribonucleic repair enzyme|polynucleotide ligase (NAD)|poly(deoxyribonucleotide):poly(deoxyribonucleotide) ligase (AMP-forming, NMN-forming)|polynucleotide ligase (nicotinamide adenine dinucleotide)|DNA joinase activity|polynucleotide synthetase (nicotinamide adenine dinucleotide)|polydeoxyribonucleotide synthase (NAD+) activity|deoxyribonucleic ligase|polynucleotide ligase|DNA repair enzyme activity|deoxyribonucleic acid joinase|polynucleotide synthetase activity|Polydeoxyribonucleotide synthase (NAD(+)) activity|deoxyribonucleic acid ligase|polydeoxyribonucleotide synthase (NAD)|deoxyribonucleic joinase Catalysis of the reaction: NAD+ + deoxyribonucleotide(n) + deoxyribonucleotide(m) = AMP + nicotinamide nucleotide + deoxyribonucleotide(n+m). GO:0003910 DNA ligase (ATP) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003910 MetaCyc:DNA-LIGASE-ATP-RXN|EC:6.5.1.1 polydeoxyribonucleotide synthase (ATP) activity|poly(deoxyribonucleotide):poly(deoxyribonucleotide) ligase (AMP-forming)|sealase activity|deoxyribonucleic-joining enzyme|deoxyribonucleic acid repair enzyme|deoxyribonucleic acid-joining enzyme|deoxyribonucleate ligase|deoxyribonucleic repair enzyme|polynucleotide ligase (ATP) activity|DNA joinase activity|deoxyribonucleic ligase|polynucleotide ligase|DNA repair enzyme activity|deoxyribonucleic acid joinase|deoxyribonucleic acid ligase|deoxyribonucleic joinase|DNA-joining enzyme Catalysis of the reaction: ATP + deoxyribonucleotide(n) + deoxyribonucleotide(m) = AMP + diphosphate + deoxyribonucleotide(n+m). CHEBI:50218 EC 3.1.4.* (phosphoric diester hydrolase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50218 CHEBI:25255 methyl methanesulfonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_25255 CHEBI:49222 (3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49222 CHEBI:49224 gamma-himachalene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49224 CHEBI:25253 methyl halides biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25253 CHEBI:49223 4-(2-carboxyphenyl)-2-oxobut-3-enoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49223 GO:0003917 DNA topoisomerase type I (single strand cut, ATP-independent) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003917 MetaCyc:5.99.1.2-RXN|EC:5.6.2.1 topoisomerase|omega-protein activity|nicking-closing enzyme activity|swivelase activity|type I DNA topoisomerase activity|DNA topoisomerase I activity|deoxyribonucleate topoisomerase|untwisting enzyme activity|type I topoisomerase activity|relaxing enzyme activity Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle. GO:0003916 DNA topoisomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003916 EC:5.6.2.- Catalysis of the transient cleavage and passage of individual DNA strands or double helices through one another, resulting a topological transformation in double-stranded DNA. GO:0003919 FMN adenylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003919 Reactome:R-HSA-196929|EC:2.7.7.2|MetaCyc:FADSYN-RXN|RHEA:17237|KEGG_REACTION:R00161 FAD pyrophosphorylase activity|FAD diphosphorylase activity|adenosine triphosphate-riboflavine mononucleotide transadenylase activity|riboflavine adenine dinucleotide adenylyltransferase activity|FAD synthetase activity|riboflavin adenine dinucleotide pyrophosphorylase activity|ATP:FMN adenylyltransferase activity|riboflavin mononucleotide adenylyltransferase activity|flavin adenine dinucleotide synthetase activity|adenosine triphosphate-riboflavin mononucleotide transadenylase activity Catalysis of the reaction: ATP + FMN = diphosphate + FAD. GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003918 MetaCyc:5.99.1.3-RXN|EC:5.6.2.2|Wikipedia:Type_II_topoisomerase DNA topoisomerase II activity|DNA topoisomerase type II activity|topoisomerase|deoxyribonucleate topoisomerase|DNA topoisomerase IV activity|topoisomerase II|DNA topoisomerase II|DNA topoisomerase (ATP-hydrolysing)|type II DNA topoisomerase activity|deoxyribonucleic topoisomerase activity Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2. GO:0003913 DNA photolyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003913 MetaCyc:DEOXYRIBODIPYRIMIDINE-PHOTOLYASE-RXN Catalysis of the repair of a photoproduct resulting from ultraviolet irradiation of two adjacent pyrimidine residues in DNA. CHEBI:50211 retinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50211 GO:0003912 DNA nucleotidylexotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003912 MetaCyc:DNA-NUCLEOTIDYLEXOTRANSFERASE-RXN|EC:2.7.7.31 nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|deoxyribonucleic acid nucleotidyltransferase activity|terminal addition enzyme activity|terminal deoxynucleotide transferase activity|terminal transferase activity|deoxyribonucleic nucleotidyltransferase activity|deoxynucleotidyl terminal transferase activity|TdT|terminal deoxynucleotidyltransferase activity|terminal deoxyribonucleotidyltransferase activity|addase activity Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). CHEBI:50210 7-methyl-GTP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50210 CHEBI:8478 propanoyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_8478 GO:0003914 DNA (6-4) photolyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003914 EC:4.1.99.13|MetaCyc:RXN-10771 Catalysis of the reaction: pyrimidine-pyrimidone (6-4) photoproduct (in DNA) = 2 pyrimidine residues (in DNA). Catalyzes the reactivation of ultraviolet-irradiated DNA. GO:0003920 GMP reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003920 KEGG_REACTION:R01134|EC:1.7.1.7|MetaCyc:GMP-REDUCT-RXN|RHEA:17185|Reactome:R-HSA-514604 guanylate reductase activity|NADPH:guanosine-5'-phosphate oxidoreductase (deaminating) activity|NADPH2:guanosine-5'-phosphate oxidoreductase (deaminating)|NADPH:GMP oxidoreductase (deaminating) activity|inosine-5'-phosphate:NADP+ oxidoreductase (aminating)|guanosine 5'-monophosphate oxidoreductase activity|guanosine monophosphate reductase activity|guanosine 5'-monophosphate reductase activity|guanosine 5'-phosphate reductase activity Catalysis of the reaction: IMP + NADP(+) + NH(4)(+) = GMP + 2 H(+) + NADPH. CHEBI:49214 alpha-himachalene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49214 GO:0003922 GMP synthase (glutamine-hydrolyzing) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003922 EC:6.3.5.2|RHEA:11680|Reactome:R-HSA-73792|MetaCyc:GMP-SYN-GLUT-RXN|Wikipedia:GMP_synthase_(glutamine-hydrolysing) guanylate synthetase (glutamine-hydrolyzing)|GMP synthetase (glutamine-hydrolyzing) activity|xanthosine-5'-phosphate:L-glutamine amido-ligase (AMP-forming)|guanosine 5'-monophosphate synthetase activity|GMP synthetase (glutamine-hydrolysing)|glutamine amidotransferase activity|guanosine monophosphate synthetase (glutamine-hydrolyzing)|GMP synthase (glutamine-hydrolysing)|xanthosine 5'-phosphate amidotransferase activity Catalysis of the reaction: ATP + XMP + L-glutamine + H2O = AMP + diphosphate + GMP + L-glutamate + 2H(+). CHEBI:25268 methyl-L-methionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25268 CHEBI:50202 naringenin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50202 GO:0003921 GMP synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003921 RHEA:18301|MetaCyc:GMP-SYN-NH3-RXN Catalysis of the reaction: ATP + XMP + NH4(+) = AMP + diphosphate + GMP + 2H(+). CHEBI:50201 (R)-naringenin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50201 CHEBI:50208 leachianone G biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50208 CHEBI:50207 sophoraflavanone B biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50207 CHEBI:50205 3,4-dihydroxybenzaldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50205 CHEBI:50209 sophoraflavanone G biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50209 CHEBI:49210 beta-himachalene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49210 CHEBI:25264 methyl-L-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25264 CHEBI:25263 methyl D-galactoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25263 CHEBI:40886 beta-L-arabinopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_40886 GO:0003928 obsolete RAB small monomeric GTPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003928 RAB small monomeric GTPase activity OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. GO:0003927 obsolete heterotrimeric G-protein GTPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003927 heterotrimeric G-protein GTPase activity OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. GTP-hydrolyzing enzymes, where GTP and GDP alternate in binding. Includes stimulatory and inhibitory G-proteins such as Gs, Gi, Go and Golf, targeting adenylate cyclase and/or potassium ion and calcium ion channels; Gq stimulating phospholipase C; transducin activating cGMP phosphodiesterase; gustducin activating cAMP phosphodiesterase. GO:0003929 obsolete RAN small monomeric GTPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003929 RAN small monomeric GTPase activity OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. GO:0003924 GTPase activity biolink:MolecularActivity go-plus goslim_yeast|goslim_drosophila|goslim_generic|goslim_chembl http://purl.obolibrary.org/obo/GO_0003924 Reactome:R-HSA-6814833|Reactome:R-HSA-5389842|Reactome:R-HSA-2584246|Reactome:R-HSA-8854173|Reactome:R-HSA-421835|Reactome:R-HSA-392133|Reactome:R-HSA-170666|Reactome:R-HSA-8854612|Reactome:R-HSA-164381|Reactome:R-HSA-203973|Reactome:R-HSA-2130725|Reactome:R-HSA-170686|Reactome:R-HSA-5623513|Reactome:R-HSA-177501|Reactome:R-HSA-380979|Reactome:R-HSA-1458485|Reactome:R-HSA-418574|RHEA:19669|Reactome:R-HSA-8868661|Reactome:R-HSA-5333615|Reactome:R-HSA-8854604|Reactome:R-HSA-8847534|Reactome:R-HSA-9645598|Reactome:R-HSA-8982025|Reactome:R-HSA-432707|Reactome:R-HSA-170685|Reactome:R-HSA-418582|Reactome:R-HSA-156923|Reactome:R-HSA-8849082|Reactome:R-HSA-5638006|Reactome:R-HSA-5658231|Reactome:R-HSA-983422|Reactome:R-HSA-5672017|Reactome:R-HSA-392212|Reactome:R-HSA-5694527|Reactome:R-HSA-5389839|Reactome:R-HSA-9640195|Reactome:R-HSA-8982021|Reactome:R-HSA-167415|Reactome:R-HSA-8854255|Reactome:R-HSA-165055|Reactome:R-HSA-6807877|Reactome:R-HSA-8854329|Reactome:R-HSA-555065|Reactome:R-HSA-1445143|Reactome:R-HSA-8847883|Reactome:R-HSA-9649736|Reactome:R-HSA-5665809|Reactome:R-HSA-8982020|Reactome:R-HSA-5419273|Reactome:R-HSA-8981353|Reactome:R-HSA-5419279|Reactome:R-HSA-428941|Reactome:R-HSA-2130641 ARF small monomeric GTPase activity|Rab small monomeric GTPase activity|RHEB small monomeric GTPase activity|dynamin GTPase activity|GTPase activity, coupled|heterotrimeric G-protein GTPase, gamma-subunit|signal-recognition-particle GTPase activity|protein-synthesizing GTPase activity, initiation|protein-synthesizing GTPase activity, termination|tubulin GTPase activity|Ras small monomeric GTPase activity|hydrolase activity, acting on acid anhydrides, acting on GTP, involved in cellular and subcellular movement|Sar small monomeric GTPase activity|protein-synthesizing GTPase activity, elongation|heterotrimeric G-protein GTPase, alpha-subunit|small monomeric GTPase activity|Ran small monomeric GTPase activity|heterotrimeric G-protein GTPase, beta-subunit|Rho small monomeric GTPase activity|heterotrimeric G-protein GTPase activity|protein-synthesizing GTPase activity Catalysis of the reaction: GTP + H2O = GDP + phosphate. GO:0003923 GPI-anchor transamidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003923 Reactome:R-HSA-162836 Catalysis of the formation of the linkage between a protein and a glycosylphosphatidylinositol anchor. The reaction probably occurs by subjecting a peptide bond to nucleophilic attack by the amino group of ethanolamine-GPI, transferring the protein from a signal peptide to the GPI anchor. GO:0003926 obsolete ARF small monomeric GTPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003926 ARF small monomeric GTPase activity OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. GO:0003925 obsolete small monomeric GTPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003925 small monomeric GTPase activity OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. Small monomeric enzymes with a molecular mass of 21 kDa that are distantly related to the alpha-subunit of heterotrimeric G-protein GTPase. They are involved in cell-growth regulation (RAS subfamily), membrane vesicle traffic and uncoating (RAB and ARF subfamilies), nuclear protein import (RAN subfamily) and organization of the cytoskeleton (Rho and Rac subfamilies). CHEBI:49204 (+)-guaia-6,9-diene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49204 CHEBI:25236 methoxybenzoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25236 CHEBI:25235 monomethoxybenzene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25235 CHEBI:49206 (1xi,4xi,5xi)-guaia-6,9-diene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49206 CHEBI:49207 (-)-guaia-6,9-diene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49207 CHEBI:25238 methoxybenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25238 CHEBI:49209 himachalene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49209 CHEBI:49202 elemental platinum biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49202 CHEBI:25230 methionine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25230 CHEBI:49201 anti-ulcer drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49201 CHEBI:64801 (R)-tetraprenyl-beta-curcumene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64801 CHEBI:64800 sativene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64800 CHEBI:64804 sesquarterpene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64804 CHEBI:64802 L-histidinal(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64802 CHEBI:39870 propylamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39870 CHEBI:8454 progoitrin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_8454 CHEBI:64809 tetrahydroxycyclohexanone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64809 CHEBI:64808 tetrahydro-4-hydroxyphenylpyruvic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64808 CHEBI:64807 tetrahydrotyrosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64807 CHEBI:64806 2-demethylmenaquinol-7 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64806 CHEBI:25248 methyl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_25248 GO:0003900 obsolete DNA-directed RNA polymerase I activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003900 DNA-directed RNA polymerase I activity OBSOLETE. Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). CHEBI:25240 methoxyflavanone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25240 CHEBI:25241 methoxyflavone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25241 CHEBI:64816 doxorubicin(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64816 GO:0003909 DNA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003909 Reactome:R-HSA-6782227|Reactome:R-HSA-5687675|Reactome:R-HSA-73931|Reactome:R-HSA-5651805|Reactome:R-HSA-5693604|Reactome:R-HSA-175258|Reactome:R-HSA-5690997|Reactome:R-HSA-5358592|Reactome:R-HSA-5649734|Reactome:R-HSA-69173|Reactome:R-HSA-174456|Reactome:R-HSA-5651789 Catalysis of the formation of a phosphodiester bond between the 3'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another. This reaction requires an energy source such as ATP or NAD+. CHEBI:64815 [(R)-2,2,3-trimethyl-2-oxocyclopent-3-en-1-yl]acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64815 CHEBI:64814 6-hydroxycamphor biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64814 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003906 Reactome:R-HSA-5649711|Reactome:R-HSA-110375|Reactome:R-HSA-5649725 deoxyribonuclease (apurinic or apyrimidinic) activity|endonuclease VIII activity|apurinic/apyrimidinic endodeoxyribonuclease activity|UV endonuclease|apyrimidinic deoxyendoribonuclease activity|apurinic deoxyendoribonuclease activity|abasic deoxyendoribonuclease activity|AP deoxyendoribonuclease activity Catalysis of the cleavage of the C-O-P bond in the AP site created when DNA glycosylase removes a damaged base, involved in the DNA base excision repair pathway (BER). GO:0003905 alkylbase DNA N-glycosylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003905 EC:3.2.2.21|MetaCyc:3.2.2.21-RXN deoxyribonucleate 3-methyladenine glycosidase II|alkylbase DNA glycosidase activity|DNA-3-methyladenine glycosylase II|DNA glycosidase II activity|AlkA|3-methyladenine DNA glycosylase II|alkylated-DNA glycohydrolase (releasing methyladenine and methylguanine)|DNA-3-methyladenine glycosidase II activity Catalysis of the reaction: DNA with alkylated base + H2O = DNA with abasic site + alkylated base. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar to remove an alkylated base, leaving an apyrimidinic or apurinic site. CHEBI:64819 [(2R)-3,3,4-trimethyl-6-oxo-3,6-dihydro-1H-pyran-2-yl]acetyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64819 GO:0003908 methylated-DNA-[protein]-cysteine S-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003908 EC:2.1.1.63|Reactome:R-HSA-73892|RHEA:24000|MetaCyc:2.1.1.63-RXN DNA-6-O-methylguanine:[protein]-L-cysteine S-methyltransferase activity|methylated-DNA-protein-cysteine S-methyltransferase activity|6-O-methylguanine-DNA methyltransferase activity|O6-alkylguanine-DNA alkyltransferase|O-6-methylguanine-DNA-alkyltransferase activity|DNA-6-O-methylguanine:protein-L-cysteine S-methyltransferase activity|MGMT Catalysis of the reaction: DNA (containing 6-O-methylguanine) + (protein)-L-cysteine = DNA (without 6-O-methylguanine) + protein S-methyl-L-cysteine. GO:0003907 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003907 CHEBI:64817 [(R)-2,2,3-trimethyl-5-oxocyclopent-3-en-1-yl]acetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64817 GO:0003902 obsolete DNA-directed RNA polymerase III activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003902 DNA-directed RNA polymerase III activity OBSOLETE. Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). GO:0003901 obsolete DNA-directed RNA polymerase II activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003901 DNA-directed RNA polymerase II activity OBSOLETE. Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). GO:0003904 deoxyribodipyrimidine photo-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003904 RHEA:10672|MetaCyc:DEOXYRIBODIPYRIMIDINE-PHOTOLYASE-RXN|EC:4.1.99.3 DNA-photoreactivating enzyme|photolyase activity|deoxyribonucleate pyrimidine dimer lyase (photosensitive)|DNA cyclobutane dipyrimidine photolyase activity|deoxyribocyclobutadipyrimidine pyrimidine-lyase activity|deoxyribonucleic photolyase activity|deoxyribodipyrimidine photolyase activity|phr A photolyase activity|deoxyribonucleic cyclobutane dipyrimidine photolyase activity|CPD photolyase activity|dipyrimidine photolyase (photosensitive)|photoreactivating enzyme activity|PRE|PhrB photolyase activity Catalysis of the reaction: cyclobutadipyrimidine (in DNA) = 2 pyrimidine residues (in DNA). This reaction represents the reactivation of irradiated DNA by light. GO:0052843 inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052843 MetaCyc:RXN-10977 Catalysis of the reaction: inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate + H2O = inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+. GO:0052842 inositol diphosphate pentakisphosphate diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052842 KEGG_REACTION:R05779|EC:3.6.1.52|RHEA:22384|Reactome:R-HSA-1855198|Reactome:R-HSA-2023971 Catalysis of the reaction: inositol diphosphate pentakisphosphate + H2O = inositol hexakisphosphate + phosphate. GO:0052841 inositol bisdiphosphate tetrakisphosphate diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052841 Reactome:R-HSA-2023973|Reactome:R-HSA-1855165 Catalysis of the reaction: inositol bisdiphosphate tetrakisphosphate + H2O = inositol diphosphate pentakisphosphate + phosphate. GO:0052840 inositol diphosphate tetrakisphosphate diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052840 EC:3.6.1.52|MetaCyc:RXN-10963|Reactome:R-HSA-1855166 Catalysis of the reaction: inositol diphosphate tetrakisphosphate + H2O = inositol 1,3,4,5,6-pentakisphosphate + phosphate. GO:0052847 inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052847 MetaCyc:RXN-10975 Catalysis of the reaction: 1,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + phosphate + H+. GO:0052846 inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052846 MetaCyc:RXN-10965 Catalysis of the reaction: 1,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 1-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + phosphate + H+. GO:0052845 inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052845 MetaCyc:RXN-10964 Catalysis of the reaction: inositol 5-diphosphate 1,2,3,4,6-pentakisphosphate + H2O = inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+. GO:0052844 inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052844 MetaCyc:RXN-10978 Catalysis of the reaction: inositol 3-diphosphate 1,2,4,5,6-pentakisphosphate + H2O = inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+. GO:0052849 NADPH-dependent curcumin reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052849 EC:1.3.1.n3|MetaCyc:RXN0-6676 Catalysis of the reaction: curcumin + NADPH + H+ = dihydrocurcumin + NADP+. GO:0052848 inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052848 MetaCyc:RXN-10976 Catalysis of the reaction: 3,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 3-diphospho-1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate + H+. CHEBI:132365 EC 1.14.11.2 (procollagen-proline dioxygenase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132365 CHEBI:132368 glucuronate acceptor biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132368 CHEBI:132367 beta-D-glucuronoside(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132367 CHEBI:74185 N-tetracosenoyl-C17-sphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74185 CHEBI:132362 citrate(4-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132362 CHEBI:132361 O-(S-[2S,4S,6S]-2,4,6-trimethyl-very-long-chain fatty acyl-pantetheine-4'-phosphoryl)serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132361 GO:0052854 medium-chain-(S)-2-hydroxy-acid oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052854 EC:1.1.3.15 medium-chain-L-alpha-hydroxy acid oxidase|medium-chain-hydroxy-acid oxidase A activity|medium-chain-hydroxy-acid oxidase B activity|oxidase, medium-chain-L-2-hydroxy acid|medium-chain-L-2-hydroxy acid oxidase|medium-chain-(S)-2-hydroxy-acid:oxygen 2-oxidoreductase|medium-chain-hydroxyacid oxidase A Catalysis of the reaction: medium-chain-(S)-2-hydroxy-acid + O2 = medium-chain-2-oxo acid + hydrogen peroxide. Medium chain refers to a chain length of between 8 and 12 carbons. GO:0052853 long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052853 Reactome:R-HSA-6787811|EC:1.1.3.15 long-chain-L-alpha-hydroxy acid oxidase|oxidase, long-chain-L-2-hydroxy acid|long-chain-hydroxyacid oxidase A|long-chain-L-2-hydroxy acid oxidase|long-chain-hydroxy-acid oxidase A activity|long-chain-(S)-2-hydroxy-acid:oxygen 2-oxidoreductase|long-chain-hydroxy-acid oxidase B activity Catalysis of the reaction: long-chain-(S)-2-hydroxy-acid + O2 = long-chain-2-oxo acid + hydrogen peroxide. Long chain refers to a chain length of 14 to 18 carbons. GO:0052852 very-long-chain-(S)-2-hydroxy-acid oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052852 EC:1.1.3.15 very-long-chain-hydroxy-acid oxidase A activity|very-long-chain-hydroxy-acid oxidase B activity|very-long-chain L-alpha-hydroxy acid oxidase|oxidase, very-long-chain L-2-hydroxy acid|very-long-chain-(S)-2-hydroxy-acid:oxygen 2-oxidoreductase|very-long-chain-hydroxyacid oxidase A|very-long-chain L-2-hydroxy acid oxidase Catalysis of the reaction: very-long-chain (S)-2-hydroxy-acid + O2 = very-long-chain 2-oxo acid + hydrogen peroxide. Very long chain refers to a chain length of greater than 18 carbons. GO:0052851 ferric-chelate reductase (NADPH) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052851 KEGG_REACTION:R09541|MetaCyc:RXN0-6555|EC:1.16.1.9|RHEA:28795 NADPH:Fe3+-EDTA reductase activity|ferric reductase, NADPH-dependent activity|iron chelate reductase activity|Fe(II):NADP+ oxidoreductase activity|ferric chelate reductase activity Catalysis of the reaction: 2 Fe3+ + NADPH = 2 Fe2+ + H+ + NADP+ . GO:1904609 cellular response to monosodium L-glutamate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904609 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosodium L-glutamate stimulus. GO:0052858 peptidyl-lysine acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052858 peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor|acetyl-phosphate:peptidyl-L-lysine 6-N-acetyltransferase activity|peptidyl-lysine N6-acetyltransferase activity|acetyl-phosphate:peptidyl-L-lysine N6-acetyltransferase activity|peptidyl-lysine N(6)-acetyltransferase activity Catalysis of the reaction: acetyl phosphate + peptidyl-L-lysine = phosphate + peptidyl-N6-acetyl-L-lysine. GO:1904608 response to monosodium L-glutamate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904608 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosodium L-glutamate stimulus. GO:0052857 NADPHX epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052857 Reactome:R-HSA-6806966|EC:5.1.99.6|RHEA:32227 Catalysis of the reaction: (R)-NADPHX = (S)-NADPHX. GO:1904606 fat cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904606 adipocyte apoptotic process|adipose cell apoptotic process|adipocyte apoptosis|adipose cell apoptosis|fat cell apoptosis Any apoptotic process in a fat cell. GO:0052856 NADHX epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052856 EC:5.1.99.6|RHEA:32215 Catalysis of the reaction: (R)-NADHX = (S)-NADHX. GO:1904605 positive regulation of advanced glycation end-product receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904605 up-regulation of advanced glycation end-product receptor activity|up-regulation of RAGE activity|activation of advanced glycation end-product receptor activity|up regulation of AGE receptor activity|positive regulation of AGE receptor activity|activation of AGE receptor activity|upregulation of RAGE activity|up regulation of advanced glycation end-product receptor activity|up-regulation of AGE receptor activity|up regulation of RAGE activity|positive regulation of RAGE activity|activation of RAGE activity|upregulation of advanced glycation end-product receptor activity|upregulation of AGE receptor activity Any process that activates or increases the frequency, rate or extent of advanced glycation end-product receptor activity. GO:0052855 ADP-dependent NAD(P)H-hydrate dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052855 EC:4.2.1.136 reduced nicotinamide adenine dinucleotide hydrate dehydratase activity|(6S)-beta-6-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase (ADP-hydrolysing)|ADP-dependent H4NAD(P)OH dehydratase activity|ADP-dependent H(4)NAD(P)OH dehydratase activity|(6S)-beta-6-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase(ADP-hydrolysing; NADH-forming) Catalysis of the reaction: (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide adenine dinucleotide + ADP = AMP + 3 H(+) + NADH + phosphate. GO:1904604 negative regulation of advanced glycation end-product receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904604 downregulation of AGE receptor activity|inhibition of RAGE activity|down-regulation of advanced glycation end-product receptor activity|down-regulation of AGE receptor activity|negative regulation of AGE receptor activity|down regulation of RAGE activity|inhibition of AGE receptor activity|downregulation of RAGE activity|downregulation of advanced glycation end-product receptor activity|down regulation of advanced glycation end-product receptor activity|inhibition of advanced glycation end-product receptor activity|down-regulation of RAGE activity|negative regulation of RAGE activity|down regulation of AGE receptor activity Any process that stops, prevents or reduces the frequency, rate or extent of advanced glycation end-product receptor activity. GO:1904603 regulation of advanced glycation end-product receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904603 regulation of RAGE activity|regulation of AGE receptor activity Any process that modulates the frequency, rate or extent of advanced glycation end-product receptor activity. GO:1904602 serotonin-activated cation-selective channel complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1904602 5-HT-3 receptor complex|5-HT3 receptor complex|5HT3 receptor complex|serotonin receptor complex|5-hydroxytryptamine receptor 3 complex A protein complex which is capable of serotonin-activated cation-selective channel activity. Mainly found in pre- and postsynaptic membranes of the brain and gastrointestinal tract. Depending on its location it transports Ca2+, Mg2+, Na+ or K+. It is always a pentamer, containing at least the 5HT3A subunit forming 5HT3A homopentamers or 5HT3A/B heteropentamers. In human, 5HT3A/C, A/D and A/E heteropentamers also exist. GO:1904601 protein localization to actin fusion focus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904601 protein localisation in actin fusion focus|protein localization in actin fusion focus|protein localisation to actin fusion focus A process in which a protein is transported to, or maintained in, a location within an actin fusion focus. GO:0052859 glucan endo-1,4-beta-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052859 EC:3.2.1.- beta-1,4-glucan hydrolase activity|beta-1,4-glucan 4-glucanohydrolase activity|endo-(1->4)-beta-D-glucanase activity|beta-1->4-glucan hydrolase activity|1,4-beta-D-glucan glucanohydrolase activity|endo-1,4-beta-D-glucanase activity|endo-(1,4)-beta-D-glucanase activity|endo-beta-1,4-glucanase activity|beta-1,4-glucanase activity|endo-1,4-beta-glucanase activity Catalysis of the random hydrolysis of (1->4) linkages in (1->4)-beta-D-glucans. GO:1904600 actin fusion focus assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904600 actin fusion focus formation The aggregation, arrangement and bonding together of a set of components to form an actin fusion focus. GO:0052850 NADPH-dependent dihydrocurcumin reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052850 MetaCyc:RXN0-6677 dihydrocurcumin reductase (NADPH) activity Catalysis of the reaction: dihydrocurcumin + NADPH+ + H+ = tetrahydrocurcumin + NADP+. GO:0052865 1-deoxy-D-xylulose 5-phosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052865 UniPathway:UPA00064 (2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate formation|(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate biosynthetic process|(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate biosynthesis|1-deoxy-D-xylulose 5-phosphate biosynthesis|1-deoxy-D-xylulose 5-phosphate anabolism|(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate anabolism|1-deoxy-D-xylulose 5-phosphate synthesis|1-deoxy-D-xylulose 5-phosphate formation|(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate synthesis The chemical reactions and pathways resulting in the formation of 1-deoxy-D-xylulose 5-phosphate, the 5-phospho derivative of 1-deoxy-D-xylulose. 1-deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway and a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis. GO:0003898 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003898 GO:0003897 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003897 GO:0052864 1-deoxy-D-xylulose 5-phosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052864 1-deoxy-D-xylulose 5-phosphate degradation|(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate degradation|(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate catabolism|1-deoxy-D-xylulose 5-phosphate breakdown|1-deoxy-D-xylulose 5-phosphate catabolism|(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate breakdown|(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate catabolic process The chemical reactions and pathways resulting in the breakdown of 1-deoxy-D-xylulose 5-phosphate, the 5-phospho derivative of 1-deoxy-D-xylulose. 1-deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway and a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis. GO:0052863 1-deoxy-D-xylulose 5-phosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052863 (2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate metabolic process|(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate metabolism|1-deoxy-D-xylulose 5-phosphate metabolism The chemical reactions and pathways involving 1-deoxy-D-xylulose 5-phosphate, the 5-phospho derivative of 1-deoxy-D-xylulose. 1-deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway and a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis. GO:0052862 glucan endo-1,4-beta-glucanase activity, C-3 substituted reducing group biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052862 MetaCyc:3.2.1.6-RXN|EC:3.2.1.6 1,3-(1,4)-beta-D-glucan 4-glucanohydrolase activity|laminaranase activity|laminarinase activity Catalysis of the endohydrolysis of (1->4)-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolysed is itself substituted at C-3. GO:0003899 DNA-directed 5'-3' RNA polymerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003899 Reactome:R-HSA-203901|Reactome:R-HSA-167113|Reactome:R-HSA-167117|Reactome:R-HSA-68913|Reactome:R-HSA-75873|Reactome:R-HSA-9697084|EC:2.7.7.6|Reactome:R-HSA-174425|Reactome:R-HSA-167121|Reactome:R-HSA-76576|Reactome:R-HSA-75869|Reactome:R-HSA-5601926|Reactome:R-HSA-6781824|Reactome:R-HSA-167115|Reactome:R-HSA-9670149|Reactome:R-HSA-74986|MetaCyc:DNA-DIRECTED-RNA-POLYMERASE-RXN|Reactome:R-HSA-427366|Reactome:R-HSA-167136|Reactome:R-HSA-75850|Reactome:R-HSA-9697085|Reactome:R-HSA-111264 DNA-directed RNA polymerase activity|C ribonucleic acid formation factors|C RNA formation factors|DNA-dependent RNA nucleotidyltransferase activity|RNA polymerase II activity|DNA-directed RNA polymerase II activity|DNA-dependent RNA polymerase activity|transcriptase|nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed) activity|RNA polymerase I activity|RNA polymerase III activity|DNA-directed RNA polymerase III activity|DNA-directed RNA polymerase I activity|deoxyribonucleic acid-dependent ribonucleic acid polymerase activity|DNA-dependent ribonucleate nucleotidyltransferase activity|RNA nucleotidyltransferase (DNA-directed) activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'. GO:0003894 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003894 GO:0052869 arachidonic acid omega-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052869 KEGG_REACTION:R07041|EC:1.14.15.3 arachidonic acid hydroxylase activity|arachidonic acid:oxygen 1-oxidoreductase activity Catalysis of the reaction: arachidonic acid + O2 + NADPH + H+ = 20-HETE + NADP+ + H2O. Arachidonic acid is also known as (5Z,8Z,11Z,14Z)-icosatetraenoic acid, and 20-HETE is also known as (5Z,8Z,11Z,14Z)-20-hydroxyicosa-5,8,11,14-tetraenoic acid. GO:1904619 response to dimethyl sulfoxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904619 response to DMSO Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dimethyl sulfoxide stimulus. GO:1904618 positive regulation of actin binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904618 upregulation of actin binding|upregulation of membrane associated actin binding|up regulation of actin binding|activation of actin binding|up regulation of membrane associated actin binding|positive regulation of membrane associated actin binding|up-regulation of actin binding|activation of membrane associated actin binding|up-regulation of membrane associated actin binding Any process that activates or increases the frequency, rate or extent of actin binding. GO:0052868 protein-lysine lysyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052868 Catalysis of the reaction: protein-lysine + protein-lysine = protein N6-(lysyl)-L-lysine + protein. This reaction is the addition of lysine group from one protein to a lysine residue in a second protein, producing N6-(lysyl)-L-lysine. GO:0003893 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003893 GO:1904617 negative regulation of actin binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904617 down regulation of actin binding|inhibition of membrane associated actin binding|downregulation of actin binding|down regulation of membrane associated actin binding|downregulation of membrane associated actin binding|down-regulation of actin binding|inhibition of actin binding|down-regulation of membrane associated actin binding|negative regulation of membrane associated actin binding Any process that stops, prevents or reduces the frequency, rate or extent of actin binding. GO:0052867 phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052867 PtdIns(1,4,5)P3 phosphatase activity|triphosphoinositide phosphatase activity|PtdIns(1,4,5)P(3) phosphatase activity|phosphatidylinositol-trisphosphatase activity|phosphatidylinositol 1,4,5-trisphosphate phosphatase activity|phosphatidyl-myo-inositol-1,4,5-trisphosphate phosphatase activity|triphosphoinositide phosphomonoesterase activity Catalysis of the reaction: phosphatidyl-1D-myo-inositol 1,4,5-trisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 1,4-bisphosphate + phosphate. GO:0003896 DNA primase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003896 EC:2.7.7.101 Catalysis of the synthesis of a short RNA primer on a DNA template, providing a free 3'-OH that can be extended by DNA-directed DNA polymerases. GO:0003895 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003895 GO:1904616 regulation of actin binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904616 regulation of membrane associated actin binding Any process that modulates the frequency, rate or extent of actin binding. GO:0052866 phosphatidylinositol phosphate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052866 phosphoinositide phosphatase activity Catalysis of the reaction: phosphatidylinositol phosphate(n) + H2O = phosphatidylinositol phosphate(n-1) + phosphate. This reaction is the removal of a phosphate group from a phosphatidylinositol phosphate. GO:1904615 cellular response to biphenyl biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904615 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biphenyl stimulus. GO:0003890 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003890 GO:1904614 response to biphenyl biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904614 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biphenyl stimulus. GO:1904613 cellular response to 2,3,7,8-tetrachlorodibenzodioxine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904613 cellular response to dioxin|cellular response to TCDD Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2,3,7,8-tetrachlorodibenzodioxine stimulus. GO:0003892 obsolete proliferating cell nuclear antigen biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003892 proliferating cell nuclear antigen|PCNA OBSOLETE. A nuclear protein that associates as a trimer and then interacts with delta DNA polymerase and epsilon DNA polymerase, acting as an auxiliary factor for DNA replication and DNA repair. GO:1904612 response to 2,3,7,8-tetrachlorodibenzodioxine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904612 response to dioxin|response to TCDD Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2,3,7,8-tetrachlorodibenzodioxine stimulus. GO:0003891 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003891 GO:1904611 cellular response to 3,3',4,4',5-pentachlorobiphenyl biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904611 cellular response to PCB 126 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',4,4',5-pentachlorobiphenyl stimulus. GO:1904610 response to 3,3',4,4',5-pentachlorobiphenyl biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904610 response to PCB 126 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',4,4',5-pentachlorobiphenyl stimulus. CHEBI:50191 trideoxyhexose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50191 CHEBI:50196 dihydroxybenzaldehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50196 CHEBI:50193 quinone imine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50193 GO:0052861 glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052861 MetaCyc:3.2.1.6-RXN|EC:3.2.1.6 1,3-(1,3)-beta-D-glucan 3-glucanohydrolase activity|laminaranase activity|laminarinase activity Catalysis of the endohydrolysis of (1->3)-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolysed is itself substituted at C-3. GO:0052860 2'-deoxymugineic-acid 3-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052860 RHEA:20065|KEGG_REACTION:R07187|EC:1.14.11.25|MetaCyc:RXN-7983 2'-deoxymugineic acid,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity Catalysis of the reaction: 2'-deoxymugineic acid + 2-oxoglutarate + O2 = 3-epihydroxy-2'-deoxymugineic acid + succinate + CO2. CHEBI:156311 trininoleoyl-monolysocardiolipin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_156311 GO:0052876 methylamine dehydrogenase (amicyanin) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052876 KEGG_REACTION:R00606|UM-BBD_reactionID:r0075|EC:1.4.9.1 amine:(acceptor) oxidoreductase (deaminating) activity|MADH activity|primary-amine dehydrogenase activity|primary-amine:(acceptor) oxidoreductase (deaminating) activity|amine dehydrogenase activity|methylamine:amicyanin oxidoreductase (deaminating) activity|methylamine dehydrogenase activity Catalysis of the reaction: methylamine + H2O + amicyanin = formaldehyde + ammonia + reduced amicyanin. GO:0052875 riboflavin reductase (NADH) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052875 MetaCyc:RXN-12445|RHEA:31455|EC:1.5.1.41|KEGG_REACTION:R09750 flavine mononucleotide reductase activity|NAD(P)H2:FMN oxidoreductase activity|riboflavin mononucleotide reductase activity|NAD(P)H:riboflavin oxidoreductase activity|NAD(P)H:FMN oxidoreductase activity|NAD(P)H-dependent FMN reductase activity|NAD(P)H-FMN reductase activity|riboflavine mononucleotide reductase activity|flavin mononucleotide reductase activity|NAD(P)H2 dehydrogenase (FMN) activity|riboflavin mononucleotide (reduced nicotinamide adenine dinucleotide) reductase activity Catalysis of the reaction: reduced riboflavin + NAD+ = riboflavin + NADH + 2 H+. GO:0052874 FMN reductase (NADH) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052874 EC:1.5.1.39|KEGG_REACTION:R05705|RHEA:21620 NADH(2) dehydrogenase (FMN) activity|NADH2 dehydrogenase (FMN)|NADH dehydrogenase (FMN) activity|NADH2:FMN oxidoreductase activity|NADH-dependent FMN reductase activity|NADH-FMN reductase activity|NADH:FMN oxidoreductase activity|NADH:flavin oxidoreductase activity|FMNH2:NAD+ oxidoreductase activity|flavine mononucleotide reductase activity|flavin mononucleotide reductase activity|NADH(2):FMN oxidoreductase activity|SsuE Catalysis of the reaction: FMNH2 + NAD+ = FMN + NADH + 2 H+. GO:0052873 FMN reductase (NADPH) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052873 EC:1.5.1.39|EC:1.5.1.38|KEGG_REACTION:R05706|RHEA:21624|Reactome:R-HSA-1222399 NADPH(2):FMN oxidoreductase activity|FMNH2:NADP+ oxidoreductase activity|NADPH(2) dehydrogenase (FMN) activity|flavine mononucleotide reductase activity|flavin mononucleotide reductase activity|NADPH2 dehydrogenase (FMN)|NADPH dehydrogenase (FMN) activity|NADPH:FMN oxidoreductase activity|NADPH2:FMN oxidoreductase activity|SsuE|NADPH-dependent FMN reductase activity|NADPH-FMN reductase activity|NADPH:flavin oxidoreductase activity Catalysis of the reaction: FMNH2 + NADP+ = FMN + NADPH + 2 H+. GO:0052879 9,12-octadecadienoate 8-hydroperoxide 8S-isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052879 KEGG_REACTION:R07062|EC:5.4.4.6|MetaCyc:1.13.11.44-RXN|RHEA:25399 (8R,9Z,12Z)-8-hydroperoxy-9,12-octadecadienoate mutase ((7S,8S,9Z,12Z)-5,8-dihydroxy-9,12-octadecadienoate-forming) activity|linoleate diol synthase activity|8-hydroperoxide isomerase activity Catalysis of the reaction: (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate = (7S,8S,9Z,12Z)-7,8-dihydroxyoctadeca-9,12-dienoate. GO:1904629 response to diterpene biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904629 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diterpene stimulus. GO:0052878 linoleate 8R-lipoxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052878 RHEA:25395|KEGG_REACTION:R07061|EC:1.13.11.60|MetaCyc:1.13.11.44-RXN 5,8-LDS (bifunctional enzyme) activity|7,8-LDS (bifunctional enzyme) activity|linoleate diol synthase activity|5,8-linoleate diol synthase (bifunctional enzyme) activity|7,8-linoleate diol synthase (bifunctional enzyme) activity Catalysis of the reaction: O(2) + linoleate = (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate. GO:1904628 cellular response to phorbol 13-acetate 12-myristate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904628 cellular response to TPA|cellular response to response to PMA|cellular response to phorbol 12-tetradecanoate 13-acetate|cellular response to tetradecanoylphorbol acetate Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phorbol 13-acetate 12-myristate stimulus. GO:1904627 response to phorbol 13-acetate 12-myristate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904627 response to phorbol 12-tetradecanoate 13-acetate|response to tetradecanoylphorbol acetate|response to TPA|response to PMA Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phorbol 13-acetate 12-myristate stimulus. GO:0052877 oxidoreductase activity, acting on the CH-NH2 group of donors, with a copper protein as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052877 EC:1.4.9.- Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and a copper protein is the acceptor. GO:1904626 positive regulation of glycine secretion, neurotransmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904626 up regulation of glycine secretion, neurotransmission|upregulation of glycine secretion, neurotransmission|up-regulation of glycine secretion, neurotransmission|activation of glycine secretion, neurotransmission Any process that activates or increases the frequency, rate or extent of glycine secretion, neurotransmission. GO:1904625 negative regulation of glycine secretion, neurotransmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904625 downregulation of glycine secretion, neurotransmission|down regulation of glycine secretion, neurotransmission|inhibition of glycine secretion, neurotransmission|down-regulation of glycine secretion, neurotransmission Any process that stops, prevents or reduces the frequency, rate or extent of glycine secretion, neurotransmission. CHEBI:49195 3beta-hydroxy-9beta-pimara-7,15-dien-19,6beta-olide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49195 GO:1904624 regulation of glycine secretion, neurotransmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904624 Any process that modulates the frequency, rate or extent of glycine secretion, neurotransmission. CHEBI:49198 2-O-sinapoyl-D-glucaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49198 GO:1904623 positive regulation of actin-dependent ATPase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904623 positive regulation of actin-activated ATPase activity|upregulation of actin-dependent ATPase activity|up-regulation of actin-activated ATPase activity|up regulation of actin-dependent ATPase activity|activation of actin-dependent ATPase activity|upregulation of actin-activated ATPase activity|up-regulation of actin-dependent ATPase activity|up regulation of actin-activated ATPase activity|activation of actin-activated ATPase activity Any process that activates or increases the frequency, rate or extent of actin-dependent ATPase activity. CHEBI:49197 2-amino-2-deoxyisochorismic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49197 GO:1904622 negative regulation of actin-dependent ATPase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904622 negative regulation of actin-activated ATPase activity|down-regulation of actin-activated ATPase activity|down regulation of actin-dependent ATPase activity|inhibition of actin-activated ATPase activity|downregulation of actin-dependent ATPase activity|down-regulation of actin-dependent ATPase activity|down regulation of actin-activated ATPase activity|downregulation of actin-activated ATPase activity|inhibition of actin-dependent ATPase activity Any process that stops, prevents or reduces the frequency, rate or extent of actin-dependent ATPase activity. GO:1904621 regulation of actin-dependent ATPase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904621 regulation of actin-activated ATPase activity Any process that modulates the frequency, rate or extent of actin-dependent ATPase activity. GO:1904620 cellular response to dimethyl sulfoxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904620 cellular response to DMSO Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dimethyl sulfoxide stimulus. CHEBI:132356 4-O-({poly[(2R)-2-glucosyl-1-glycerylphosphonato]}-[2R]-1-glycerylphosphonato)-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl undecaprenyl diphosphate polyanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132356 CHEBI:132358 1alpha-hydroxytestosterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132358 CHEBI:50185 fatty acid synthesis inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50185 CHEBI:50183 P450 inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50183 GO:0052872 tocotrienol omega-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052872 EC:1.14.13.- tocotrienol 13-hydroxylase activity Catalysis of the reaction: tocotrienol + O2 + NADPH + H+ = 13'-hydroxy-tocotrienol + NADP+ + H2O . GO:0052871 alpha-tocopherol omega-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052871 MetaCyc:RXN-11003 alpha-tocopherol 13-hydroxylase activity Catalysis of the reaction: alpha-tocopherol + O2 + NADPH + H+ = 13'-hydroxy-alpha-tocopherol + NADP+ + H2O . CHEBI:50188 provitamin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50188 GO:0052870 tocopherol omega-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052870 tocopherol 13-hydroxylase activity Catalysis of the reaction: tocopherol + O2 + NADPH + H+ = 13'-hydroxy-tocopherol + NADP+ + H2O . GO:0003876 AMP deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003876 Reactome:R-HSA-76590|MetaCyc:AMP-DEAMINASE-RXN|RHEA:14777|EC:3.5.4.6 adenosine monophosphate deaminase activity|5-adenylic acid deaminase activity|5-AMP deaminase activity|adenosine 5-monophosphate deaminase activity|adenylate deaminase activity|AMP aminohydrolase activity|adenylic deaminase activity|adenylate deaminase reaction|5-adenylate deaminase activity|adenylate desaminase activity|adenyl deaminase activity|adenosine 5-phosphate aminohydrolase activity|adenylic acid deaminase activity|myoadenylate deaminase activity|adenylate aminohydrolase activity|AMP aminase activity Catalysis of the reaction: AMP + H2O = IMP + NH3. GO:0052887 7,9,9'-tricis-neurosporene:quinone oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052887 KEGG_REACTION:R09658|EC:1.3.5.6|MetaCyc:RXN-11357 ZDS activity|9,9'-di-cis-zeta-carotene desaturase activity|zeta-carotene desaturase activity Catalysis of the reaction: 7,9,9'-tri-cis-neurosporene + a quinone = 7,9,7',9'-tetra-cis-lycopene + a quinol. GO:0003875 ADP-ribosylarginine hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003875 MetaCyc:ADP-RIBOSYLARGININE-HYDROLASE-RXN|EC:3.2.2.19|RHEA:20784 protein ADP-ribosylarginine hydrolase activity|omega-protein-N-(ADP-D-ribosyl)-L-arginine ADP-ribosylhydrolase activity|ADPribosylarginine hydrolase activity|protein-nomega-(ADP-D-ribosyl)-L-arginine ADP-ribosylhydrolase activity|ADP-ribose-L-arginine cleaving enzyme activity|N(omega)-(ADP-D-ribosyl)-L-arginine ADP-ribosylhydrolase activity|ADP-ribose-L-arginine cleavage enzyme activity|nomega-(ADP-D-ribosyl)-L-arginine ADP-ribosylhydrolase activity Catalysis of the reaction: N2-(ADP-D-ribosyl)-L-arginine + H2O = L-arginine + ADP-ribose. GO:0052886 9,9'-dicis-carotene:quinone oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052886 EC:1.3.5.6|KEGG_REACTION:R09656|MetaCyc:RXN-11356 ZDS activity|9,9'-di-cis-zeta-carotene desaturase activity|zeta-carotene desaturase activity Catalysis of the reaction: 9,9'-di-cis-zeta-carotene + a quinone = 7,9,9'-tri-cis-neurosporene + a quinol. GO:0003878 ATP citrate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003878 MetaCyc:PWY-5172|RHEA:21160|Reactome:R-HSA-75848|MetaCyc:ATP-CITRATE-PRO-S--LYASE-RXN|KEGG_REACTION:R00352|EC:2.3.3.8 citric cleavage enzyme activity|ATP-citric lyase activity|adenosine triphosphate citrate lyase activity|ATP:citrate oxaloacetate-lyase ((pro-S)-CH(2)COO(-)->acetyl-CoA) (ATP- dephosphorylating) activity|ATP-citrate (pro-S)-lyase activity|ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-rightacetyl-CoA] (ATP-dephosphorylating)|citrate cleavage enzyme activity|ATP citrate (pro-S)-lyase activity|ATP-citrate (pro-S-)-lyase activity|acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP- phosphorylating) activity|citrate-ATP lyase activity|acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating]|acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP-phosphorylating) Catalysis of the reaction: acetyl-CoA + ADP + H(+) + oxaloacetate + phosphate = ATP + citrate + CoA. GO:0052885 all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052885 EC:3.1.1.64|RHEA:31771|KEGG_REACTION:R08388|MetaCyc:RXN-12550 retinoid isomerohydrolase activity|retinol isomerase activity|all-trans-retinylester 11-cis isomerohydrolase activity|all-trans-retinyl ester acylhydrolase, 11-cis retinol forming activity|all-trans-retinol isomerase:hydrolase activity Catalysis of the reaction: H(2)O + all-trans-retinyl ester = 11-cis-retinol + fatty acid. GO:0003877 ATP adenylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003877 EC:2.7.7.53|MetaCyc:ATP-ADENYLYLTRANSFERASE-RXN|RHEA:16577 AP-4-A phosphorylase activity|adenine triphosphate adenylyltransferase activity|dinucleoside oligophosphate alphabeta-phosphorylase activity|diadenosinetetraphosphate alphabeta-phosphorylase activity|diadenosinetetraphosphate alpha-beta-phosphorylase activity|diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase activity|bis(5'-nucleosyl)-tetraphosphate phosphorylase (NDP-forming) activity|ADP:ATP adenylyltransferase activity|diadenosine 5',5'''-P(1),P(4)-tetraphosphate phosphorylase activity|diadenosine 5',5'''-P1,P4-tetraphosphate alphabeta-phosphorylase (ADP-forming) Catalysis of the reaction: ADP + ATP = phosphate + P(1),P(4)-bis(5'-adenosyl)tetraphosphate. GO:0052884 all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052884 EC:3.1.1.64|RHEA:31775|Reactome:R-HSA-2453833 retinoid isomerohydrolase activity|retinol isomerase activity|all-trans-retinyl-palmitate hydrolase activity|all-trans-retinol isomerase:hydrolase activity Catalysis of the reaction: H(2)O + all-trans-retinyl palmitate = 11-cis-retinol + H(+) + palmitate. GO:0003872 6-phosphofructokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003872 Reactome:R-HSA-70467|RHEA:16109|EC:2.7.1.11|MetaCyc:6PFRUCTPHOS-RXN fructose 6-phosphokinase activity|phosphofructokinase (phosphorylating)|6-phosphofructose 1-kinase activity|fructose 6-phosphate kinase activity|phosphohexokinase activity|PFK|phosphofructokinase I activity|phospho-1,6-fructokinase activity|D-fructose-6-phosphate 1-phosphotransferase activity|6-phosphofructokinase reduction|ATP-dependent phosphofructokinase activity|ATP:D-fructose-6-phosphate 1-phosphotransferase activity|nucleotide triphosphate-dependent phosphofructokinase activity Catalysis of the reaction: ATP + D-fructose-6-phosphate = ADP + D-fructose 1,6-bisphosphate. GO:0003871 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003871 EC:2.1.1.14|MetaCyc:HOMOCYSMET-RXN|KEGG_REACTION:R04405|RHEA:21196 methionine synthase (cobalamin-independent) activity|MetE|homocysteine methylase activity|methyltransferase, tetrahydropteroylglutamate-homocysteine transmethylase activity|cobalamin-independent methionine synthase activity|tetrahydropteroylglutamate-homocysteine transmethylase activity|tetrahydropteroyltriglutamate methyltransferase activity|methyltetrahydropteroylpolyglutamate:homocysteine methyltransferase activity|5-methyltetrahydropteroyltri-L-glutamate:L-homocysteine S-methyltransferase activity Catalysis of the reaction: 5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine = L-methionine + tetrahydropteroyltri-L-glutamate. GO:1904639 cellular response to resveratrol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904639 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a resveratrol stimulus. GO:0052889 9,9'-di-cis-zeta-carotene desaturation to 7,9,7',9'-tetra-cis-lycopene biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052889 KEGG_REACTION:R07511|MetaCyc:RXN-12242 7,9,7',9'-tetra-cis-lycopene biosynthesis from 9,9'-di-cis-zeta-carotene|9,9'-di-cis-zeta-carotene catabolism to 7,9,7',9'-tetra-cis-lycopene The series of reactions in which 9,9'-di-cis-zeta-carotene is desaturated to 7,9,9'-tri-cis-neurosporene, and then 7,9,7',9'-tetra-cis-lycopene. The overall reaction for this process is: 9,9'-di-cis-zeta-carotene + 2 quinone = 2 quinol + 7,9,7',9'-tetra-cis-lycopene. GO:0003874 6-pyruvoyltetrahydropterin synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003874 MetaCyc:4.2.3.12-RXN|Reactome:R-HSA-1474184|EC:4.2.3.12|RHEA:22048|KEGG_REACTION:R04286 2-amino-4-oxo-6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydroxypteridine triphosphate lyase activity|2-amino-4-oxo-6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydroxypteridine triphosphate-lyase (6-pyruvoyl-5,6,7,8-tetrahydropterin-forming)|PTPS activity|6-pyruvoyl tetrahydrobiopterin synthase activity Catalysis of the reaction: 7,8-dihydroneopterin 3'-triphosphate = 6-pyruvoyl-5,6,7,8-tetrahydropterin + H(+) + triphosphate. GO:0052888 obsolete dihydroorotate oxidase (fumarate) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052888 KEGG_REACTION:R01867|RHEA:30059|MetaCyc:RXN-9929|EC:1.3.98.1 dihydroorotate oxidase activity|dihydroorotate dehydrogenase activity|DHodehase activity|DHOD activity|DHOdase activity|dihydroorotate oxidase (fumarate) activity|dihydoorotic acid dehydrogenase activity OBSOLETE. Catalysis of the reaction: (S)-dihydroorotate + fumarate = orotate + succinate. GO:1904638 response to resveratrol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904638 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a resveratrol stimulus. GO:0003873 6-phosphofructo-2-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003873 MetaCyc:6-PHOSPHOFRUCTO-2-KINASE-RXN|Reactome:R-HSA-71802|KEGG_REACTION:R02732|EC:2.7.1.105|RHEA:15653 fructose 6-phosphate 2-kinase activity|6-phosphofructo-2-kinase (phosphorylating)|6-phosphofructose 2-kinase activity|ATP:beta-D-fructose-6-phosphate 2-phosphotransferase activity|ATP:D-fructose-6-phosphate 2-phosphotransferase activity|phosphofructokinase 2 activity Catalysis of the reaction: beta-D-fructose 6-phosphate + ATP = beta-D-fructose 2,6-bisphosphate + ADP + 2 H(+). GO:1904637 cellular response to ionomycin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904637 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ionomycin stimulus. GO:1904636 response to ionomycin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904636 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ionomycin stimulus. CHEBI:49187 (-)-abscisic aldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49187 GO:0003870 5-aminolevulinate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003870 EC:2.3.1.37|MetaCyc:5-AMINOLEVULINIC-ACID-SYNTHASE-RXN|KEGG_REACTION:R00830|RHEA:12921|Reactome:R-HSA-189442 delta-aminolevulinate synthetase activity|5-aminolevulinic acid synthase activity|delta-ALA synthetase activity|5-aminolevulinate synthetase activity|aminolevulinic acid synthase activity|aminolevulinate synthetase activity|ALA synthetase activity|aminolevulinic synthetase activity|delta-aminolevulinic acid synthetase activity|delta-aminolevulinate synthase activity|5-aminolevulinic acid synthetase activity|ALAS activity|delta-aminolevulinic synthetase activity|alpha-aminolevulinic acid synthase activity|aminolevulinate synthase activity|aminolevulinic acid synthetase activity|ALA synthase activity|delta-aminolevulinic acid synthase activity|succinyl-CoA:glycine C-succinyltransferase (decarboxylating) Catalysis of the reaction: glycine + H(+) + succinyl-CoA = 5-aminolevulinate + CO(2) + CoA. GO:1904635 positive regulation of glomerular visceral epithelial cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904635 activation of podocyte apoptotic process|up-regulation of podocyte apoptotic process|activation of podocyte apoptosis|positive regulation of glomerular visceral epithelial cell apoptosis|up-regulation of glomerular podocyte apoptotic process|up regulation of glomerular visceral epithelial cell apoptotic process|activation of glomerular visceral epithelial cell apoptotic process|positive regulation of podocyte apoptosis|upregulation of glomerular podocyte apoptosis|activation of glomerular visceral epithelial cell apoptosis|up regulation of podocyte apoptosis|up-regulation of glomerular visceral epithelial cell apoptosis|upregulation of glomerular podocyte apoptotic process|positive regulation of podocyte apoptotic process|up regulation of podocyte apoptotic process|up regulation of glomerular podocyte apoptosis|up-regulation of glomerular visceral epithelial cell apoptotic process|positive regulation of glomerular podocyte apoptosis|upregulation of podocyte apoptosis|upregulation of glomerular visceral epithelial cell apoptosis|up regulation of glomerular podocyte apoptotic process|activation of glomerular podocyte apoptosis|activation of glomerular podocyte apoptotic process|positive regulation of glomerular podocyte apoptotic process|upregulation of podocyte apoptotic process|upregulation of glomerular visceral epithelial cell apoptotic process|up-regulation of podocyte apoptosis|up-regulation of glomerular podocyte apoptosis|up regulation of glomerular visceral epithelial cell apoptosis Any process that activates or increases the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process. GO:1904634 negative regulation of glomerular visceral epithelial cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904634 downregulation of glomerular visceral epithelial cell apoptotic process|negative regulation of podocyte apoptosis|inhibition of glomerular podocyte apoptosis|down-regulation of podocyte apoptosis|inhibition of glomerular podocyte apoptotic process|negative regulation of glomerular visceral epithelial cell apoptosis|down-regulation of glomerular visceral epithelial cell apoptosis|negative regulation of podocyte apoptotic process|down-regulation of podocyte apoptotic process|down regulation of glomerular podocyte apoptosis|down-regulation of glomerular visceral epithelial cell apoptotic process|downregulation of podocyte apoptosis|downregulation of glomerular podocyte apoptosis|down regulation of glomerular podocyte apoptotic process|down regulation of podocyte apoptosis|downregulation of podocyte apoptotic process|inhibition of glomerular visceral epithelial cell apoptotic process|inhibition of glomerular visceral epithelial cell apoptosis|downregulation of glomerular podocyte apoptotic process|down regulation of podocyte apoptotic process|inhibition of podocyte apoptotic process|inhibition of podocyte apoptosis|down-regulation of glomerular podocyte apoptosis|negative regulation of glomerular podocyte apoptosis|down regulation of glomerular visceral epithelial cell apoptosis|down-regulation of glomerular podocyte apoptotic process|negative regulation of glomerular podocyte apoptotic process|downregulation of glomerular visceral epithelial cell apoptosis|down regulation of glomerular visceral epithelial cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process. CHEBI:49189 pristanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49189 GO:1904633 regulation of glomerular visceral epithelial cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904633 regulation of glomerular podocyte apoptosis|regulation of podocyte apoptosis|regulation of glomerular podocyte apoptotic process|regulation of podocyte apoptotic process|regulation of glomerular visceral epithelial cell apoptosis Any process that modulates the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process. GO:1904632 cellular response to glucoside biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904632 cellular response to glucosides Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucoside stimulus. CHEBI:49188 2-methyl-branched fatty aldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49188 GO:0062211 root regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062211 The the regeneration process by which a damaged or lost root regrows or re-differentiates. This process may occur via de-differentiation and subsequent reprogramming of somatic cells or activation of existing undifferentiated (meristematic) cells to form a new root meristem and subsequently new root. GO:1904631 response to glucoside biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904631 response to glucosides Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucoside stimulus. GO:0062210 shoot regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062210 shoot system regeneration The regeneration process by which a damaged or lost shoot regrows or re-differentiates. This process may occur via de-differentiation and subsequent reprogramming of somatic cells or activation of existing undifferentiated (meristematic) cells to produce a new shoot meristem and subsequently a new shoot. GO:1904630 cellular response to diterpene biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904630 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diterpene stimulus. GO:0062213 peroxynitrite isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062213 Catalysis of the reaction: peroxynitrite = nitrate. GO:1904640 response to methionine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904640 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methionine stimulus. CHEBI:132320 S-hexadecanoyl-4'-phosphopantetheine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132320 GO:0062212 regulation of mitotic DNA replication initiation from early origin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062212 regulation of early replication origin firing Any process that modulates the frequency, rate or extent of firing from an early origin of replication involved in mitotic DNA replication. CHEBI:49190 2-methylpentadecanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49190 CHEBI:132322 S-(3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl)-4'-phosphopantetheine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132322 CHEBI:132321 S-choloyl-4'-phosphopantetheine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132321 CHEBI:49192 pimarane diterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49192 CHEBI:132324 20-HETrE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132324 CHEBI:50170 3-hydroxy-5alpha-pregnan-20-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50170 CHEBI:49191 momilactone A biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49191 CHEBI:132323 19-HETrE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132323 CHEBI:49194 3-(1-carboxyvinyloxy)anthranilic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49194 CHEBI:49193 diterpene lactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49193 CHEBI:132325 21-HDoHE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132325 CHEBI:50171 3-hydroxy-5beta-pregnan-20-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50171 GO:0052883 tyrosine ammonia-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052883 EC:4.3.1.23|RHEA:24906|EC:4.3.1.25 L-tyrosine ammonia-lyase activity|TAL activity|tyrase activity Catalysis of the reaction: L-tyrosine = NH(4)(+) + trans-4-coumarate. GO:0003879 ATP phosphoribosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003879 RHEA:18473|EC:2.4.2.17|MetaCyc:ATPPHOSPHORIBOSYLTRANS-RXN phosphoribosyl ATP:pyrophosphate phosphoribosyltransferase activity|adenosine triphosphate phosphoribosyltransferase activity|phosphoribosyl ATP synthetase activity|1-(5-phospho-D-ribosyl)-ATP:diphosphate phospho-alpha-D-ribosyl-transferase activity|phosphoribosyladenosine triphosphate:pyrophosphate phosphoribosyltransferase activity|phosphoribosyladenosine triphosphate pyrophosphorylase activity|phosphoribosyl-ATP:pyrophosphate-phosphoribosyl phosphotransferase activity|phosphoribosyl-ATP pyrophosphorylase activity|phosphoribosyl-ATP diphosphorylase activity|phosphoribosyladenosine triphosphate synthetase activity Catalysis of the reaction: 1-(5-phospho-D-ribosyl)-ATP + diphosphate = ATP + 5-phospho-alpha-D-ribose 1-diphosphate. GO:0052882 oxidoreductase activity, acting on phosphorus or arsenic in donors, with a copper protein as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052882 EC:1.20.9.- Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a copper protein. CHEBI:50177 dermatologic drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50177 GO:0052881 4-hydroxyphenylacetate 3-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052881 RHEA:30595|EC:1.14.14.9|MetaCyc:RXN-8505|UM-BBD_reactionID:r0301 4 HPA 3-hydroxylase activity|p-hydroxyphenylacetate hydroxylase activity|p-hydroxyphenylacetate hydroxylase (FAD) activity|p-hydroxyphenylacetate 3-hydroxylase activity|4-hydroxyphenylacetic acid-3-hydroxylase activity|p-hydroxyphenylacetate 3-hydroxylase (FAD) activity|4-hydroxyphenylacetate,FADH:oxygen oxidoreductase (3-hydroxylating) activity Catalysis of the reaction: (4-hydroxyphenyl)acetate + FADH(2) + O(2) = 3,4-dihydroxyphenylacetate + FAD + H(+) + H(2)O. CHEBI:50176 keratolytic drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50176 GO:0052880 oxidoreductase activity, acting on diphenols and related substances as donors, with copper protein as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052880 EC:1.10.9.- Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces a copper protein. GO:0003887 DNA-directed DNA polymerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003887 Reactome:R-HSA-5656158|EC:2.7.7.7|Reactome:R-HSA-164513|Reactome:R-HSA-6782208|Reactome:R-HSA-73932|Reactome:R-HSA-5693593|Reactome:R-HSA-110317|Reactome:R-HSA-110368|Reactome:R-HSA-5649723|Reactome:R-HSA-69116|Reactome:R-HSA-68950|Reactome:R-HSA-164505|Reactome:R-HSA-174427|Reactome:R-HSA-110311|Reactome:R-HSA-110319|Reactome:R-HSA-5687640|Reactome:R-HSA-5656148|Reactome:R-HSA-5655892|Reactome:R-HSA-174444|Reactome:R-HSA-5655965|Reactome:R-HSA-5653840|Reactome:R-HSA-6786166|Reactome:R-HSA-5358579|Reactome:R-HSA-5691001|Reactome:R-HSA-111253|Reactome:R-HSA-5687360|Reactome:R-HSA-5649883|MetaCyc:DNA-DIRECTED-DNA-POLYMERASE-RXN DNA polymerase alpha|DNA nucleotidyltransferase (DNA-directed) activity|kappa DNA polymerase activity|epsilon DNA polymerase activity|Taq DNA polymerase|sequenase|DNA polymerase V activity|mu DNA polymerase activity|lambda DNA polymerase activity|nu DNA polymerase activity|sigma DNA polymerase activity|DNA replicase activity|DNA duplicase activity|DNA polymerase beta|DNA-dependent DNA polymerase activity|theta DNA polymerase activity|Klenow fragment|alpha DNA polymerase activity|deoxyribonucleic duplicase activity|Tca DNA polymerase|duplicase|Taq Pol I|zeta DNA polymerase activity|deoxyribonucleic acid duplicase activity|delta DNA polymerase activity|gamma DNA-directed DNA polymerase activity|DNA polymerase I|DNA polymerase III|DNA polymerase gamma|iota DNA polymerase activity|deoxyribonucleic polymerase I|DNA polymerase II|eta DNA polymerase activity|beta DNA polymerase activity|deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and a 3'hydroxyl group. GO:0052898 N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052898 EC:1.5.3.15|RHEA:25864 Catalysis of the reaction: H(2)O + N(1)-acetylspermidine + O(2) = 1,3-diaminopropane + 4-acetamidobutanal + H(2)O(2). GO:0003886 DNA (cytosine-5-)-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003886 RHEA:13681|MetaCyc:2.1.1.73-RXN|EC:2.1.1.37 DNA 5-cytosine methylase activity|deoxyribonucleic methylase activity|methylphosphotriester-DNA methyltransferase activity|S-adenosyl-L-methionine:DNA (cytosine-5-)-methyltransferase activity|DNA cytosine C5 methylase activity|DNA cytosine methylase activity|cytosine-specific DNA methyltransferase activity|deoxyribonucleic (cytosine-5-)-methyltransferase activity|DNA-cytosine methyltransferase activity|cytosine DNA methyltransferase activity|DNA cytosine C(5) methylase activity|deoxyribonucleic acid (cytosine-5-)-methyltransferase activity|cytosine 5-methyltransferase activity|cytosine DNA methylase activity|modification methylase activity|site-specific DNA-methyltransferase (cytosine-specific) activity|DNA-cytosine 5-methylase activity|type II DNA methylase activity|restriction-modification system activity Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing cytosine = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine. GO:0052897 N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052897 KEGG_REACTION:R09075|MetaCyc:RXN-10463|EC:1.5.3.15|RHEA:25972 N(8)-acetylspermidine oxidase (propane-1,3-diamine-forming) activity Catalysis of the reaction: H(2)O + N(8)-acetylspermidine + O(2) = 1,3-diaminopropane + 4-acetamidobutanal + H(2)O(2). GO:0052896 spermidine oxidase (propane-1,3-diamine-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052896 KEGG_REACTION:R01914|EC:1.5.3.14|RHEA:25820|MetaCyc:RXN-10747 spermidine:(acceptor) oxidoreductase activity|polyamine oxidase (propane-1,3-diamine-forming) activity Catalysis of the reaction: H(2)O + O(2) + spermidine = 1,3-diaminopropane + 4-aminobutanal + H(2)O(2). GO:0003889 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003889 CHEBI:50169 brexanolone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50169 GO:0052895 N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052895 MetaCyc:POLYAMINE-OXIDASE-RXN|EC:1.5.3.16 N1-acetylspermine oxidase activity Catalysis of the reaction: N1-acetylspermine + oxygen + H2O = N1-acetylspermidine + 3-aminopropanal + hydrogen peroxide. CHEBI:50168 3-hydroxypregnan-20-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50168 GO:0003888 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003888 GO:0003883 CTP synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003883 EC:6.3.4.2|RHEA:16597|MetaCyc:CTPSYN-RXN|Reactome:R-HSA-504054|Reactome:R-HSA-73647 UTP--ammonia ligase activity|UTP:ammonia ligase (ADP-forming)|CTP synthetase activity|uridine triphosphate aminase activity|cytidine 5'-triphosphate synthetase activity|cytidine triphosphate synthetase activity Catalysis of the reaction: ATP + UTP + NH3 = ADP + phosphate + CTP. GO:0003882 CDP-diacylglycerol-serine O-phosphatidyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003882 RHEA:16913|MetaCyc:PHOSPHASERSYN-RXN|EC:2.7.8.8 CDPdiacylglycerol-serine O-phosphatidyltransferase activity|CDP-diglycerine-serine O-phosphatidyltransferase activity|CDP-diglyceride:serine phosphatidyltransferase activity|phosphatidylserine synthase activity|CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|CDPdiglyceride-serine O-phosphatidyltransferase activity|cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|phosphatidylserine synthetase activity|PS synthase activity|CDP-diglyceride-L-serine phosphatidyltransferase activity|serine exchange enzyme Catalysis of the reaction: CDP-diacylglycerol + L-serine = CMP + O-sn-phosphatidyl-L-serine. GO:0003885 D-arabinono-1,4-lactone oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003885 RHEA:23756|MetaCyc:1.1.3.37-RXN|EC:1.1.3.37|KEGG_REACTION:R02715 D-arabinono-1,4-lactone:oxygen oxidoreductase activity Catalysis of the reaction: D-arabinono-1,4-lactone + O(2) = dehydro-D-arabinono-1,4-lactone + H(2)O(2) + H(+). GO:0003884 D-amino-acid oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003884 Reactome:R-HSA-389821|EC:1.4.3.3|MetaCyc:D-AMINO-ACID-OXIDASE-RXN|RHEA:21816 D-amino-acid:oxygen oxidoreductase (deaminating)|L-amino acid:O2 oxidoreductase activity|new yellow enzyme Catalysis of the reaction: a D-amino acid + H2O + O2 = a 2-oxo acid + NH3 + hydrogen peroxide. GO:1904649 regulation of fat cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904649 regulation of adipose cell apoptosis|regulation of fat cell apoptosis|regulation of adipocyte apoptosis|regulation of adipose cell apoptotic process|regulation of adipocyte apoptotic process Any process that modulates the frequency, rate or extent of fat cell apoptotic process. GO:0052899 N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052899 MetaCyc:RXN-10460|RHEA:25868|EC:1.5.3.13 N(1)-acetylpolyamine oxidase activity|polyamine oxidase activity Catalysis of the reaction: H(2)O + N(1),N(12)-diacetylspermine + O(2) = 3-acetamidopropanal + H(2)O(2) + N(1)-acetylspermidine. CHEBI:49174 2-hydroxy-3-methylhexadecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49174 GO:1904648 cellular response to rotenone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904648 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rotenone stimulus. CHEBI:49173 2-hydroxy-3-methylacyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49173 GO:1904647 response to rotenone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904647 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rotenone stimulus. GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003881 Reactome:R-HSA-1482976|RHEA:11580|EC:2.7.8.11|MetaCyc:2.7.8.11-RXN|KEGG_REACTION:R01802 cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:myo-inositol 3-phosphatidyltransferase activity|CDP-diglyceride:inositol transferase activity|CDP-diacylglycerol:myo-inositol-3-phosphatidyltransferase activity|CDP-DG:inositol transferase activity|cytidine diphosphoglyceride-inositol transferase activity|CDP-diacylglycerol--inositol phosphatidyltransferase activity|CDPdiacylglycerol-inositol 3-phosphatidyltransferase activity|phosphatidylinositol synthase activity|CDP diglyceride-inositol phosphatidyltransferase activity|CDP-diglyceride-inositol transferase activity|CDP-diacylglycerol:myo-inositol 3-phosphatidyltransferase activity|cytidine diphosphoglyceride-inositol phosphatidyltransferase activity|cytidine diphosphodiglyceride-inositol phosphatidyltransferase activity Catalysis of the reaction: myo-inositol + CDP-diacylglycerol = 1-phosphatidyl-1D-myo-inositol + CMP + H(+). GO:1904646 cellular response to amyloid-beta biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904646 cellular response to beta-amyloids|cellular response to beta-amyloid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a amyloid-beta stimulus. CHEBI:49175 2-hydroxy-3-methylhexadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49175 GO:1904645 response to amyloid-beta biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904645 response to beta-amyloids|response to beta-amyloid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a amyloid-beta stimulus. GO:0003880 protein C-terminal carboxyl O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003880 C-terminal protein carboxyl methyltransferase activity Catalysis of the transfer of a methyl group to the oxygen atom of a carboxyl group at the C-terminal of a protein. GO:1904644 cellular response to curcumin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904644 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a curcumin stimulus. CHEBI:49178 2,3-dihydroxy-2,3-dihydrobenzoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49178 GO:1904643 response to curcumin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904643 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a curcumin stimulus. CHEBI:49177 (6R)-dehydrovomifoliol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49177 GO:0062200 RAM/MOR signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062200 MOR signaling pathway|RAM signaling pathway|morphogenesis Orb6 network An intracellular signaling pathway that regulates interphase polarized growth and cell separation at the end of cytokinesis through activation of the NDR1/2-related kinase. GO:1904642 cellular response to dinitrophenol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904642 cellular response to dinitrophenols Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dinitrophenol stimulus. GO:1904641 response to dinitrophenol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904641 response to dinitrophenols Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dinitrophenol stimulus. CHEBI:49179 cis-3,4-didehydroadipoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49179 GO:1904651 positive regulation of fat cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904651 up-regulation of adipose cell apoptotic process|activation of adipose cell apoptotic process|activation of adipose cell apoptosis|up-regulation of fat cell apoptotic process|activation of fat cell apoptosis|activation of fat cell apoptotic process|up-regulation of adipocyte apoptosis|positive regulation of adipose cell apoptosis|positive regulation of fat cell apoptosis|up regulation of adipose cell apoptosis|up-regulation of adipocyte apoptotic process|up regulation of fat cell apoptosis|positive regulation of adipose cell apoptotic process|up regulation of adipose cell apoptotic process|upregulation of adipocyte apoptosis|up regulation of fat cell apoptotic process|upregulation of adipose cell apoptosis|upregulation of adipocyte apoptotic process|upregulation of fat cell apoptosis|up regulation of adipocyte apoptosis|upregulation of adipose cell apoptotic process|upregulation of fat cell apoptotic process|positive regulation of adipocyte apoptosis|up-regulation of adipose cell apoptosis|up regulation of adipocyte apoptotic process|up-regulation of fat cell apoptosis|positive regulation of adipocyte apoptotic process|activation of adipocyte apoptotic process|activation of adipocyte apoptosis Any process that activates or increases the frequency, rate or extent of fat cell apoptotic process. GO:0062202 Labd-13(16),14-diene-9-ol synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062202 RHEA:62184 Catalysis of the reaction: peregrinol diphosphate = diphosphate + labd-13(16),14-diene-9-ol. GO:1904650 negative regulation of fat cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904650 down-regulation of adipose cell apoptosis|negative regulation of adipose cell apoptosis|down-regulation of adipocyte apoptotic process|negative regulation of adipocyte apoptotic process|down-regulation of fat cell apoptosis|negative regulation of fat cell apoptosis|down-regulation of adipose cell apoptotic process|negative regulation of adipose cell apoptotic process|inhibition of adipocyte apoptotic process|inhibition of adipocyte apoptosis|down-regulation of fat cell apoptotic process|downregulation of adipose cell apoptosis|downregulation of fat cell apoptosis|down regulation of adipose cell apoptosis|down regulation of adipocyte apoptosis|down regulation of fat cell apoptosis|downregulation of adipose cell apoptotic process|downregulation of fat cell apoptotic process|downregulation of adipocyte apoptosis|down regulation of adipose cell apoptotic process|down regulation of adipocyte apoptotic process|inhibition of adipose cell apoptotic process|inhibition of adipose cell apoptosis|down regulation of fat cell apoptotic process|inhibition of fat cell apoptosis|inhibition of fat cell apoptotic process|downregulation of adipocyte apoptotic process|down-regulation of adipocyte apoptosis|negative regulation of adipocyte apoptosis Any process that stops, prevents or reduces the frequency, rate or extent of fat cell apoptotic process. GO:0062201 actin wave biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062201 A cellular anatomical entity that is part of the actin cytoskeleton and results in a wave-like propagation of actin networks. It consists of dynamic structures traveling on the ventral (substrate-attached) side of the cell during cell migration, cytokinesis, adhesion and neurogenesis. GO:0062204 (13S)-vitexifolin A synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062204 RHEA:40027 Catalysis of the reaction:9alpha-copalyl diphosphate + H2O = (13S)-vitexifolin A + diphosphate. GO:0062203 Viteagnusin D synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062203 RHEA:62180 Catalysis of the reaction: H2O + peregrinol diphosphate = diphosphate + viteagnusin D. GO:0062206 manoyl oxide synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062206 EC:4.2.3.190|RHEA:54516 Catalysis of the reaction: 8-hydroxycopalyl diphosphate = (13R)-manoyl oxide + diphosphate. CHEBI:49181 (R)-1,2-didecanoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49181 GO:0062205 miltiradiene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062205 EC:4.2.3.131|MetaCyc:RXN-13338|RHEA:33983 multiradiene synthase activity Catalysis of the reaction: (+)-copalyl diphosphate = diphosphate + miltiradiene. CHEBI:49180 cis-3,4-didehydroadipoyl-CoA semialdehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49180 GO:0062208 positive regulation of pattern recognition receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062208 Any process that decreases the rate, frequency or extent of a pattern recognition receptor signaling pathway. CHEBI:49183 phosphatidylcholine(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49183 GO:0062207 regulation of pattern recognition receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062207 Any process that modulates the rate, frequency or extent of a pattern recognition receptor signaling pathway. CHEBI:49182 1,5-anhydro-D-mannitol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49182 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052890 EC:1.3.8.- Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a flavin. CHEBI:50163 alpha-glutamyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50163 GO:0062209 spatial regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062209 crossover interference|regulation of spatial distribution of meiotic DSB formation involved in reciprocal meiotic recombination|regulation of spatial distribution of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination|DSB interference Any process that modulates the distribution of sites along the chromosome where meiotic DNA double-strand break formation takes place as part of reciprocal meiotic recombination. CHEBI:50160 steroid acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50160 GO:0052894 norspermine:oxygen oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052894 MetaCyc:RXN-10464|EC:1.5.3.16 norspermine oxidase activity Catalysis of the reaction: norspermine + oxygen + H2O = norspermidine + 3-aminopropanal + hydrogen peroxide. GO:0052893 N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052893 MetaCyc:RXN-10465|EC:1.5.3.14|RHEA:25996 polyamine oxidase (propane-1,3-diamine-forming) activity Catalysis of the reaction: N1-acetylspermine + oxygen + H2O = N-(3-acetamidopropyl)-4-aminobutanal + propane-1,3-diamine + hydrogen peroxide. CHEBI:50166 D-gamma-glutamyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50166 GO:0052892 aromatic (S)-hydroxynitrile lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052892 EC:4.1.2.47|RHEA:54660|KEGG_REACTION:R09359|MetaCyc:RXN-11732 oxynitrilase activity|(S)-hydroxynitrile lyase activity|(S)-selective hydroxynitrile lyase activity|(S)-oxynitrilase activity|hydroxynitrile lyase activity|(S)-cyanohydrin producing hydroxynitrile lyase activity|(S)-cyanohydrin carbonyl-lyase (cyanide forming) activity Catalysis of the reaction: an aromatic (S)-hydroxynitrile = an aromatic aldehyde + cyanide. GO:0052891 aliphatic (S)-hydroxynitrile lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052891 EC:4.1.2.47|MetaCyc:RXN-11731 oxynitrilase activity|(S)-hydroxynitrile lyase activity|(S)-selective hydroxynitrile lyase activity|(S)-oxynitrilase activity|hydroxynitrile lyase activity|(S)-cyanohydrin producing hydroxynitrile lyase activity|(S)-cyanohydrin carbonyl-lyase (cyanide forming) activity Catalysis of the reaction: an aliphatic (S)-hydroxynitrile = an aliphatic aldehyde or ketone + cyanide. CHEBI:50164 gamma-glutamyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50164 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003854 RHEA:24076|MetaCyc:1.1.1.145-RXN|Reactome:R-HSA-196350|EC:1.1.1.145|Reactome:R-HSA-193789|Reactome:R-HSA-196372|Reactome:R-HSA-192097|Reactome:R-HSA-193816 3beta-HSDH|5-ene-3-beta-hydroxysteroid dehydrogenase activity|delta5-3beta-hydroxysteroid dehydrogenase activity|steroid-delta5-3beta-ol dehydrogenase activity|3beta-hydroxy-5-ene-steroid dehydrogenase activity|3-beta-hydroxy-D5-steroid dehydrogenase activity|3beta-hydroxy-delta5-steroid dehydrogenase activity|3beta-hydroxy steroid dehydrogenase/isomerase activity|3beta-hydroxy-5-ene-steroid oxidoreductase activity|3beta-hydroxy-delta5-steroid:NAD+ 3-oxidoreductase activity|3beta-hydroxy-5-ene steroid dehydrogenase activity|3beta-hydroxy-delta5-C27-steroid dehydrogenase/isomerase activity|3beta-hydroxy-delta5-C27-steroid oxidoreductase|progesterone reductase activity|3-beta-hydroxy-5-ene steroid dehydrogenase activity Catalysis of the reaction: a 3-beta-hydroxy-delta(5)-steroid + NAD+ = a 3-oxo-delta(5)-steroid + NADH + H(+). GO:0003853 2-methylacyl-CoA dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003853 RHEA:13261|EC:1.3.99.12|MetaCyc:2-METHYLACYL-COA-DEHYDROGENASE-RXN branched-chain acyl-CoA dehydrogenase activity|2-methylbutanoyl-CoA:acceptor oxidoreductase activity|2-methyl branched chain acyl-CoA dehydrogenase activity|2-methylbutanoyl-CoA:(acceptor) oxidoreductase activity Catalysis of the reaction: 2-methylbutanoyl-CoA + acceptor = 2-methylbut-2-enoyl-CoA + reduced acceptor. GO:0003856 3-dehydroquinate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003856 EC:4.2.3.4|KEGG_REACTION:R03083|MetaCyc:3-DEHYDROQUINATE-SYNTHASE-RXN|RHEA:21968 Catalysis of the reaction: 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate = 3-dehydroquinate + phosphate. GO:0003855 3-dehydroquinate dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003855 RHEA:21096|KEGG_REACTION:R03084|MetaCyc:3-DEHYDROQUINATE-DEHYDRATASE-RXN|EC:4.2.1.10 DHQase|3-dehydroquinate hydrolase activity|5-dehydroquinate dehydratase activity|5-dehydroquinase activity|3-dehydroquinase activity|dehydroquinate dehydratase activity|5-dehydroquinate hydro-lyase activity|dehydroquinase activity|3-dehydroquinate hydro-lyase activity|3-dehydroquinate hydro-lyase (3-dehydroshikimate-forming) Catalysis of the reaction: 3-dehydroquinate = 3-dehydroshikimate + H(2)O. CHEBI:50157 (5-hydroxyindol-3-yl)acetaldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50157 GO:0003850 2-deoxyglucose-6-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003850 MetaCyc:3.1.3.68-RXN|EC:3.1.3.68|RHEA:22236|KEGG_REACTION:R02587 2-deoxy-D-glucose-6-phosphate phosphohydrolase activity|2-deoxyglucose-6-phosphate phosphatase activity Catalysis of the reaction: 2-deoxy-D-glucose-6-phosphate + H2O = 2-deoxy-D-glucose + phosphate. GO:0003852 2-isopropylmalate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003852 MetaCyc:2-ISOPROPYLMALATESYN-RXN|RHEA:21524|EC:2.3.3.13|KEGG_REACTION:R01213 3-carboxy-3-hydroxy-4-methylpentanoate 3-methyl-2-oxobutanoate-lyase (CoA-acetylating) activity|alpha-isopropylmalate synthase activity|alpha-IPM synthetase activity|isopropylmalate synthetase activity|acetyl-CoA:3-methyl-2-oxobutanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)|isopropylmalate synthase activity|alpha-isopropylmalate synthetase activity|alpha-isopropylmalic synthetase activity Catalysis of the reaction: 3-methyl-2-oxobutanoate + acetyl-CoA + H(2)O = (2S)-2-isopropylmalate + CoA + H(+). GO:0003851 2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003851 MetaCyc:2.4.1.45-RXN|EC:2.4.1.47|RHEA:10856 UDPgalactose:2-(2-hydroxyacyl)sphingosine 1-beta-D-galactosyl-transferase activity|uridine diphosphogalactose-2-hydroxyacylsphingosine galactosyltransferase activity|cerebroside synthase activity|UDP-galactose-ceramide galactosyltransferase activity|UDPgalactose-2-hydroxyacylsphingosine galactosyltransferase activity|UDPgalactose:ceramide galactosyltransferase activity|UDP-galactose:2-(2-hydroxyacyl)sphingosine 1-beta-D-galactosyl-transferase activity|UDPgalactose:2-2-hydroxyacylsphingosine galactosyltransferase activity Catalysis of the reaction: UDP-galactose + 2-(2-hydroxyacyl)sphingosine = UDP + 1-(beta-D-galactosyl)-2-(2-hydroxyacyl)sphingosine. GO:1904659 glucose transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904659 glucose transport The process in which glucose is transported across a membrane. CHEBI:25196 mercury molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25196 CHEBI:132306 (1R)-1,4,5,10-tetrahydrophenazine-1-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132306 GO:1904658 positive regulation of sensory perception of sweet taste biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904658 up-regulation of sweet taste perception|activation of sweet taste perception|up regulation of sensory perception of sweet taste|activation of sensory perception of sweet taste|positive regulation of sweet taste perception|up regulation of sweet taste perception|up-regulation of sensory perception of sweet taste|upregulation of sweet taste perception|upregulation of sensory perception of sweet taste Any process that activates or increases the frequency, rate or extent of sensory perception of sweet taste. CHEBI:25195 mercury atom biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_25195 GO:1904657 negative regulation of sensory perception of sweet taste biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904657 downregulation of sensory perception of sweet taste|negative regulation of sweet taste perception|down-regulation of sweet taste perception|down-regulation of sensory perception of sweet taste|inhibition of sensory perception of sweet taste|downregulation of sweet taste perception|down regulation of sweet taste perception|inhibition of sweet taste perception|down regulation of sensory perception of sweet taste Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of sweet taste. GO:1904656 regulation of sensory perception of sweet taste biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904656 regulation of sweet taste perception Any process that modulates the frequency, rate or extent of sensory perception of sweet taste. CHEBI:49164 (6S,9R)-vomifoliol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49164 GO:0062231 positive regulation of larval somatic muscle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062231 Any process that increases the rate, frequency or extent of larval somatic muscle development. GO:1904655 positive regulation of lung alveolus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904655 up regulation of alveolarization|positive regulation of alveolarization|activation of alveolarization|upregulation of lung alveolus development|upregulation of alveologenesis|up-regulation of alveolarization|up regulation of lung alveolus development|up-regulation of alveologenesis|activation of alveologenesis|activation of lung alveolus development|upregulation of alveolarization|positive regulation of alveologenesis|up-regulation of lung alveolus development|up regulation of alveologenesis Any process that activates or increases the frequency, rate or extent of lung alveolus development. CHEBI:49167 anti-asthmatic drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49167 GO:0062230 negative regulation of larval somatic muscle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062230 Any process that decreases the rate, frequency or extent of larval somatic muscle development. GO:1904654 negative regulation of lung alveolus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904654 downregulation of alveologenesis|down regulation of alveologenesis|inhibition of alveologenesis|negative regulation of alveolarization|down-regulation of alveolarization|down regulation of lung alveolus development|downregulation of lung alveolus development|inhibition of alveolarization|down-regulation of lung alveolus development|negative regulation of alveologenesis|down-regulation of alveologenesis|down regulation of alveolarization|inhibition of lung alveolus development|downregulation of alveolarization Any process that stops, prevents or reduces the frequency, rate or extent of lung alveolus development. CHEBI:132309 S-butyryl-4'-phosphopantetheine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132309 CHEBI:49169 D-dopa biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49169 GO:1904653 regulation of lung alveolus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904653 regulation of alveologenesis|regulation of alveolarization Any process that modulates the frequency, rate or extent of lung alveolus development. GO:0062233 F2-isoprostane catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062233 The chemical reactions and pathways resulting in the breakdown of F2-isoprostane. GO:0062232 prostanoid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062232 The chemical reactions and pathways resulting in the breakdown of prostanoids. GO:1904652 protein localization to cell division site involved in cell separation after cytokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904652 Any protein localization to cell division site that is involved in cell separation after cytokinesis. CHEBI:49168 dopa biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49168 CHEBI:25197 mercury cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25197 GO:1904662 positive regulation of sensory perception of bitter taste biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904662 up regulation of sensory perception of bitter taste|upregulation of bitter taste perception|upregulation of sensory perception of bitter taste|up regulation of bitter taste perception|activation of bitter taste perception|positive regulation of bitter taste perception|activation of sensory perception of bitter taste|up-regulation of sensory perception of bitter taste|up-regulation of bitter taste perception Any process that activates or increases the frequency, rate or extent of sensory perception of bitter taste. GO:0062235 axonemal basal plate assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062235 axoneme basal plate assembly|basal plate assembly|axonemal basal plate formation The aggregation, arrangement and bonding together of a set of components to form an axonemal basal plate. GO:0062234 platelet activating factor catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062234 PAF catabolic process|2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine catabolic process The chemical reactions and pathways resulting in the breakdown of platelet activating factor, 2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine. GO:1904661 negative regulation of sensory perception of bitter taste biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904661 downregulation of sensory perception of bitter taste|down regulation of sensory perception of bitter taste|down regulation of bitter taste perception|inhibition of sensory perception of bitter taste|downregulation of bitter taste perception|down-regulation of bitter taste perception|negative regulation of bitter taste perception|down-regulation of sensory perception of bitter taste|inhibition of bitter taste perception Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of bitter taste. GO:0062237 protein localization to postsynapse biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062237 Any process in which a protein is transported to, and/or maintained at the postsynapse, the part of a synapse that is part of the post-synaptic cell. GO:1904660 regulation of sensory perception of bitter taste biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904660 regulation of bitter taste perception Any process that modulates the frequency, rate or extent of sensory perception of bitter taste. GO:0062236 ionocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062236 The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an ionocyte. Ionocytes are specialized epithelial cells that contribute to osmotic homeostasis. GO:0062239 heterochromatin-nuclear membrane anchor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062239 heterochromatin-nuclear membrane tether activity|nuclear membrane-heterochromatin tether activity|nuclear membrane-heterochromatin anchor activity Interacting selectively and non-covalently with heterochromatin and the nuclear inner membrane, in order to establish and maintain the heterochromatin location and organization. CHEBI:132302 (8S,9R)-EET biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132302 GO:0062238 Smp focus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062238 Smp dot A DNA-binding ribonucleoprotein complex that contains a lncRNA complementary to the bound chromosomal locus and is involved in the tethering homologous chromosomes together during chromosome pairing at meiotic prophase I. CHEBI:49172 1,2-diglyceride biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49172 CHEBI:132303 (8R,9S)-EET biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132303 GO:0003858 3-hydroxybutyrate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003858 KEGG_REACTION:R01361|Reactome:R-HSA-73912|Reactome:R-HSA-5696457|MetaCyc:3-HYDROXYBUTYRATE-DEHYDROGENASE-RXN|Reactome:R-HSA-73920|EC:1.1.1.30|RHEA:20521 D-beta-hydroxybutyrate dehydrogenase activity Catalysis of the reaction: (R)-3-hydroxybutanoate + NAD(+) = acetoacetate + H(+) + NADH. GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003857 Reactome:R-HSA-77342|Reactome:R-HSA-77254|Reactome:R-HSA-193455|Reactome:R-HSA-389995|UM-BBD_enzymeID:e0664|Reactome:R-HSA-70837|MetaCyc:OHACYL-COA-DEHYDROG-RXN|Reactome:R-HSA-6809264|Reactome:R-HSA-77323|Reactome:R-HSA-508369|EC:1.1.1.35|Reactome:R-HSA-390251|Reactome:R-HSA-193508|Reactome:R-HSA-77312|Reactome:R-HSA-77303|RHEA:22432|Reactome:R-HSA-77331|Reactome:R-HSA-77283 3-oxoacyl-thioester reductase activity|beta-keto-reductase activity|beta-ketoacyl-CoA reductase|beta-hydroxyacylcoenzyme A dehydrogenase activity|beta-hydroxybutyrylcoenzyme A dehydrogenase activity|L-3-hydroxyacyl CoA dehydrogenase activity|L-3-hydroxyacyl coenzyme A dehydrogenase activity|beta-hydroxyacyl-coenzyme A synthetase activity|beta-hydroxyacyl dehydrogenase activity Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD+ = 3-oxoacyl-CoA + NADH + H(+). GO:0003859 3-hydroxybutyryl-CoA dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003859 EC:4.2.1.55|MetaCyc:3-HYDROXBUTYRYL-COA-DEHYDRATASE-RXN|RHEA:17849|KEGG_REACTION:R03027 D-3-hydroxybutyryl-CoA dehydratase activity|D-3-hydroxybutyryl coenzyme A dehydratase activity|(3R)-3-hydroxybutanoyl-CoA hydro-lyase activity|(3R)-3-hydroxybutanoyl-CoA hydro-lyase (crotonoyl-CoA-forming)|enoyl coenzyme A hydrase (D)|crotonase activity Catalysis of the reaction: (R)-3-hydroxybutanoyl-CoA = crotonoyl-CoA + H(2)O. GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003865 Reactome:R-HSA-9705713|Reactome:R-HSA-9705714|MetaCyc:1.3.99.5-RXN|Reactome:R-HSA-469659|EC:1.3.99.5 4-ene-3-ketosteroid-5alpha-oxidoreductase activity|delta4-3-oxosteroid-5alpha-reductase|3-oxo-5alpha-steroid:acceptor delta4-oxidoreductase activity|3-oxo-5alpha-steroid 4-dehydrogenase activity|delta4-3-oxo steroid reductase activity|testosterone 5alpha-reductase|steroid 5alpha-reductase|steroid 5-alpha-reductase activity|5alpha-reductase|delta4-3-ketosteroid5alpha-oxidoreductase activity|3-oxo-5alpha-steroid:(acceptor) delta4-oxidoreductase activity|delta4-3-keto steroid 5alpha-reductase activity|3-keto-delta4-steroid-5alpha-reductase activity|delta4-5alpha-dehydrogenase activity|3-oxosteroid delta4-dehydrogenase|steroid delta4-5alpha-reductase activity|steroid 5 alpha reductase|3-oxo-5alpha-steroid delta4-dehydrogenase activity Catalysis of the reaction: a 3-oxo-5-alpha-steroid + acceptor = a 3-oxo-delta(4)-steroid + reduced acceptor. GO:0003864 3-methyl-2-oxobutanoate hydroxymethyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003864 RHEA:11824|EC:2.1.2.11|MetaCyc:3-CH3-2-OXOBUTANOATE-OH-CH3-XFER-RXN oxopantoate hydroxymethyltransferase activity|5,10-methylenetetrahydrofolate:3-methyl-2-oxobutanoate hydroxymethyltransferase activity|5,10-methylene tetrahydrofolate:alpha-ketoisovalerate hydroxymethyltransferase activity|ketopantoate hydroxymethyltransferase activity|dehydropantoate hydroxymethyltransferase activity|alpha-ketoisovalerate hydroxymethyltransferase activity Catalysis of the reaction: 5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate = tetrahydrofolate + 2-dehydropantoate. GO:0003867 4-aminobutyrate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003867 RHEA:23352|MetaCyc:GABATRANSAM-RXN|Reactome:R-HSA-916855 gamma-aminobutyric acid transaminase activity|glutamate-succinic semialdehyde transaminase activity|4-aminobutyric acid aminotransferase activity|gamma-aminobutyric transaminase activity|GABA transaminase activity|GABA transferase activity|aminobutyrate transaminase activity|gamma-aminobutyrate aminotransaminase activity|gamma-aminobutyric acid aminotransferase activity|gamma-aminobutyrate transaminase activity|4-aminobutyrate aminotransferase activity|4-aminobutanoate transaminase activity|gamma-amino-N-butyrate transaminase activity|GABA aminotransferase activity|aminobutyrate aminotransferase activity|beta-alanine aminotransferase Catalysis of the reaction: 4-aminobutanoate + amino group acceptor = succinate semialdehyde + amino acid. GO:0003866 3-phosphoshikimate 1-carboxyvinyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003866 RHEA:21256|MetaCyc:2.5.1.19-RXN|KEGG_REACTION:R03460|EC:2.5.1.19 phosphoenolpyruvate:3-phosphoshikimate 5-O-(1-carboxyvinyl)-transferase activity|5-enolpyruvylshikimate-3-phosphate synthase activity|3-enol-pyruvoylshikimate-5-phosphate synthase activity|EPSP synthase activity Catalysis of the reaction: 3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate. GO:0003861 3-isopropylmalate dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003861 EC:4.2.1.33|MetaCyc:3-ISOPROPYLMALISOM-RXN|RHEA:32287 (2R,3S)-3-isopropylmalate hydro-lyase activity|(2R,3S)-3-isopropylmalate hydro-lyase (2-isopropylmaleate-forming)|alpha-isopropylmalate isomerase activity|isopropylmalate isomerase activity|alpha-IPM isomerase activity|beta-isopropylmalate dehydratase activity Catalysis of the reaction: (2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate. GO:0003860 3-hydroxyisobutyryl-CoA hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003860 RHEA:20888|Reactome:R-HSA-70881|EC:3.1.2.4|MetaCyc:3-HYDROXYISOBUTYRYL-COA-HYDROLASE-RXN 3-hydroxy-isobutyryl CoA hydrolase activity|HIB CoA deacylase activity|3-hydroxy-2-methylpropanoyl-CoA hydrolase activity Catalysis of the reaction: 3-hydroxy-2-methylpropanoyl-CoA + H2O = CoA + 3-hydroxy-2-methylpropanoate. GO:0003863 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003863 RHEA:13457|MetaCyc:1.2.4.4-RXN|EC:1.2.4.4 branched-chain alpha-oxo acid dehydrogenase activity|alpha-oxoisocaproate dehydrogenase activity|3-methyl-2-oxobutanoate:dihydrolipoyllysine-residue (2-methylpropanoyl)transferase-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-2-methylpropanoylating)|alpha-ketoisocaproic-alpha-keto-alpha-methylvaleric dehydrogenase activity|2-oxoisovalerate (lipoate) dehydrogenase activity|alpha-keto-alpha-methylvalerate dehydrogenase activity|BCKDH activity|3-methyl-2-oxobutanoate:lipoamide oxidoreductase (decarboxylating and acceptor-2-methylpropanoylating) activity|branched-chain keto acid dehydrogenase activity|branched-chain 2-oxo acid dehydrogenase activity|branched-chain ketoacid dehydrogenase activity|2-oxoisocaproate dehydrogenase activity|BCOAD activity|branched-chain (-2-oxoacid) dehydrogenase (BCD) activity|branched-chain 2-keto acid dehydrogenase activity|alpha-ketoisocaproate dehydrogenase activity|alpha-ketoisovalerate dehydrogenase activity|alpha-ketoisocaproic dehydrogenase activity|3-methyl-2-oxobutanoate dehydrogenase (lipoamide) activity|branched chain keto acid dehydrogenase activity|dehydrogenase, 2-oxoisovalerate (lipoate) activity|branched-chain alpha-keto acid dehydrogenase activity|dehydrogenase, branched chain alpha-keto acid activity Catalysis of the reaction: 3-methyl-2-oxobutanoate + lipoamide = S-(2-methylpropanoyl)dihydrolipoamide + CO2. GO:0003862 3-isopropylmalate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003862 EC:1.1.1.85|RHEA:32271|MetaCyc:3-ISOPROPYLMALDEHYDROG-RXN beta-IPM dehydrogenase activity|3-carboxy-2-hydroxy-4-methylpentanoate:NAD+ oxidoreductase activity|beta-isopropylmalic enzyme|IPMDH|IMDH activity|beta-isopropylmalate dehydrogenase activity|(2R,3S)-3-isopropylmalate:NAD+ oxidoreductase activity|threo-Ds-3-isopropylmalate dehydrogenase activity Catalysis of the reaction: 3-carboxy-2-hydroxy-4-methylpentanoate + NAD+ = 3-carboxy-4-methyl-2-oxopentanoate + NADH + H+. GO:1904669 ATP export biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904669 ATP efflux The directed movement of ATP out of a cell or organelle. CHEBI:132316 S-dodecanoyl-4'-phosphopantetheine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132316 GO:1904668 positive regulation of ubiquitin protein ligase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904668 up regulation of APC-fizzy related complex activity|up-regulation of ubiquitin protein ligase activity|activation of protein ubiquitination activity|positive regulation of protein ubiquitination activity|up-regulation of ubiquitin ligase activity|up-regulation of E3|upregulation of ubiquitin protein ligase activity|activation of APC-Cdc20 complex activity|upregulation of APC-fizzy related complex activity|activation of APC-fizzy related complex activity|activation of E3|upregulation of ubiquitin ligase activity|up-regulation of protein ubiquitination activity|positive regulation of APC-fizzy related complex activity|positive regulation of E3|up regulation of ubiquitin protein ligase activity|up regulation of E3|up-regulation of APC-fizzy related complex activity|activation of ubiquitin protein ligase activity|upregulation of protein ubiquitination activity|up regulation of ubiquitin ligase activity|activation of anaphase-promoting complex activity|activation of ubiquitin ligase activity|positive regulation of ubiquitin ligase activity|upregulation of E3|up regulation of protein ubiquitination activity Any process that activates or increases the frequency, rate or extent of ubiquitin protein ligase activity. CHEBI:132319 S-tetradecanoyl-4'-phosphopantetheine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132319 GO:1904667 negative regulation of ubiquitin protein ligase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904667 inhibition of ubiquitin protein ligase activity|inhibition of E3|inhibition of ubiquitin ligase activity|negative regulation of anaphase-promoting complex activity during mitotic cell cycle|negative regulation of protein ubiquitination activity|down-regulation of protein ubiquitination activity|negative regulation of cyclosome activity during mitotic cell cycle|negative regulation of APC-Cdc20 complex activity|negative regulation of APC-fizzy related complex activity|negative regulation of APC/C activity during mitotic cell cycle|down regulation of ubiquitin protein ligase activity|inhibition of protein ubiquitination activity|negative regulation of E3|down-regulation of E3|down regulation of ubiquitin ligase activity|downregulation of ubiquitin protein ligase activity|downregulation of ubiquitin ligase activity|downregulation of E3|negative regulation of APC activity during mitotic cell cycle|negative regulation of mitotic anaphase-promoting complex activity|down regulation of protein ubiquitination activity|down-regulation of ubiquitin protein ligase activity|down regulation of E3|negative regulation of ubiquitin ligase activity|down-regulation of ubiquitin ligase activity|downregulation of protein ubiquitination activity Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin protein ligase activity. GO:1904666 regulation of ubiquitin protein ligase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904666 regulation of ubiquitin ligase activity|regulation of APC-fizzy related complex activity|regulation of E3|regulation of protein ubiquitination activity Any process that modulates the frequency, rate or extent of ubiquitin protein ligase activity. CHEBI:49156 (6S)-vomifoliol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49156 GO:1904665 positive regulation of N-terminal peptidyl-methionine acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904665 Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-methionine acetylation. GO:1904664 negative regulation of N-terminal peptidyl-methionine acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904664 Any process that stops, prevents or reduces the frequency, rate or extent of N-terminal peptidyl-methionine acetylation. GO:1904663 regulation of N-terminal peptidyl-methionine acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904663 Any process that modulates the frequency, rate or extent of N-terminal peptidyl-methionine acetylation. GO:1904673 negative regulation of somatic stem cell population maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904673 downregulation of somatic stem cell population maintenance|down regulation of somatic stem cell population maintenance|inhibition of somatic stem cell population maintenance|down-regulation of somatic stem cell population maintenance Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell population maintenance. GO:0062224 positive regulation of somatic muscle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062224 Any process that increases the rate, frequency or extent of somatic muscle development. GO:1904672 regulation of somatic stem cell population maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904672 Any process that modulates the frequency, rate or extent of somatic stem cell population maintenance. GO:0062223 regulation of somatic muscle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062223 Any process that regulates the rate, frequency or extent of somatic muscle development. GO:1904671 negative regulation of cell differentiation involved in stem cell population maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904671 negative regulation of cell differentiation involved in maintenance of pluripotency|down-regulation of cell differentiation involved in maintenance of pluripotency|inhibition of cell differentiation involved in stem cell population maintenance|downregulation of cell differentiation involved in maintenance of pluripotency|down regulation of cell differentiation involved in maintenance of pluripotency|down regulation of cell differentiation involved in stem cell population maintenance|downregulation of cell differentiation involved in stem cell population maintenance|inhibition of cell differentiation involved in maintenance of pluripotency|down-regulation of cell differentiation involved in stem cell population maintenance Any negative regulation of cell differentiation that is involved in stem cell population maintenance. GO:0062226 regulation of adult somatic muscle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062226 Any process that modulates the rate, frequency or extent of adult somatic muscle development. CHEBI:132311 S-hexanoyl-4'-phosphopantetheine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132311 GO:1904670 actin filament polymerization involved in mitotic actomyosin contractile ring assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904670 Any actin filament polymerization that is involved in mitotic actomyosin contractile ring assembly. CHEBI:132310 S-acyl-4'-phosphopantetheine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132310 GO:0062225 negative regulation of somatic muscle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062225 Any process that decreases the rate, frequency or extent of somatic muscle development. CHEBI:132313 S-decanoyl-4'-phosphopantetheine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132313 GO:0062228 negative regulation of adult somatic muscle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062228 Any process that decreases the rate, frequency or extent of adult somatic muscle development. CHEBI:132312 S-octanoyl-4'-phosphopantetheine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132312 GO:0062227 positive regulation of adult somatic muscle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062227 Any process that increases the rate, frequency or extent of adult somatic muscle development. CHEBI:49161 (6R)-vomifoliol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49161 GO:0062229 regulation of larval somatic muscle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062229 Any process that modulates the rate, frequency or extent of larval somatic muscle development. CHEBI:49160 (6R,9S)-vomifoliol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49160 CHEBI:50141 bronchoconstrictor agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50141 GO:0003869 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003869 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003868 UM-BBD_reactionID:r0298|RHEA:16189|EC:1.13.11.27|MetaCyc:4-HYDROXYPHENYLPYRUVATE-DIOXYGENASE-RXN|Reactome:R-HSA-71163 p-hydroxyphenylpyruvate hydroxylase activity|p-hydroxyphenylpyruvic oxidase activity|4-hydroxyphenylpyruvate hydroxylase activity|4-hydroxyphenylpyruvic acid dioxygenase activity|p-hydroxyphenylpyruvic hydroxylase activity|4-hydroxyphenylpyruvate:oxygen oxidoreductase (hydroxylating, decarboxylating)|p-hydroxyphenylpyruvic acid hydroxylase activity|p-hydroxyphenylpyruvate dioxygenase activity|p-hydroxyphenylpyruvate oxidase activity Catalysis of the reaction: 4-hydroxyphenylpyruvate + O2 = homogentisate + CO2. CHEBI:74105 aldono-1,5-lactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74105 CHEBI:74106 erucoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74106 CHEBI:74109 (11Z,14Z)-3-oxoicosa-11,14-dienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74109 CHEBI:64782 (+)-artemisinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64782 CHEBI:15809 dolichyl D-mannosyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15809 CHEBI:64781 3-heptaprenyl-sn-glycero-1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64781 CHEBI:15808 12-dehydrotetracycline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15808 CHEBI:64786 (+)-6-exo-hydroxycamphor biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64786 CHEBI:15805 D-octopine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15805 CHEBI:64785 [(2R)-3,3,4-trimethyl-6-oxo-3,6-dihydro-1H-pyran-2-yl]acetyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64785 CHEBI:88752 cholesteryl (5Z,8Z,11Z)-icosatrienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88752 CHEBI:64784 [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl]acetyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64784 CHEBI:15807 beta-L-arabinose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15807 CHEBI:64783 (+)-artemisinic alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64783 CHEBI:15801 (R)-2-hydroxyglutarate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15801 CHEBI:64789 3-(4-hydroxycyclohex-2-en-1-ylidene)pyruvate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64789 CHEBI:88756 cholesteryl gamma-linolenate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88756 CHEBI:64788 3,4-dihydro-4-hydroxyphenylpyruvate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64788 CHEBI:64787 (+)-6-endo-hydroxycamphor biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64787 CHEBI:15802 alpha,beta-didehydrotryptophan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15802 CHEBI:74100 N-[(9Z)-octadecenoyl]sphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74100 CHEBI:74116 2-hydroxystearoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74116 CHEBI:74115 2-hydroxypalmitoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74115 CHEBI:74118 2-hydroxytetracosanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74118 CHEBI:74117 2-hydroxybehenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74117 CHEBI:74119 (3S)-3-methyl-2-oxo-3-phenylpropanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74119 CHEBI:64793 2,2'-dioxospirilloxanthin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64793 CHEBI:64792 2-oxospirilloxanthin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64792 CHEBI:64791 tetrahydrotyrosine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64791 CHEBI:64790 tetrahydro-4-hydroxyphenylpyruvate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64790 CHEBI:64797 alpha-muurolene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64797 CHEBI:64796 2-deoxy-scyllo-inosose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64796 CHEBI:64795 phytosphingosine 1-phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64795 CHEBI:64794 salicin-6-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64794 CHEBI:64799 beta-copaene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64799 CHEBI:64798 gamma-muurolene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64798 CHEBI:74114 (11Z,14Z,17Z)-3-oxoicosatrienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74114 CHEBI:74127 (13Z)-3-oxodocosenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74127 CHEBI:74126 (11Z)-eicosenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74126 CHEBI:74128 (15Z)-tetracosenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74128 CHEBI:15827 N(omega)-(ADP-D-ribosyl)-L-arginine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15827 CHEBI:15826 16alpha-hydroxyprogesterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15826 CHEBI:15829 L-serine O-sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15829 CHEBI:15822 17alpha-estradiol 3-glucosiduronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15822 CHEBI:15825 3-methylbut-2-enal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15825 CHEBI:15824 D-fructose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15824 CHEBI:15821 5-hydroxy-6-methylpyridine-3-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15821 CHEBI:15820 GDP-alpha-D-mannose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15820 CHEBI:74120 Gly-Met biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74120 CHEBI:74122 (3S)-3-methyl-2-oxo-3-phenylpropanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74122 CHEBI:74138 2-hydroxystearoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74138 CHEBI:74137 2-hydroxyhexadecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74137 CHEBI:15819 N(6)-(dimethylallyl)adenosine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15819 CHEBI:88764 ethyl butyrate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88764 CHEBI:15816 D-arginine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15816 CHEBI:15815 quinolin-4-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15815 CHEBI:15817 semiquinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15817 CHEBI:15812 dolichyl beta-D-glucosyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15812 CHEBI:15811 O-phospho-L-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15811 CHEBI:74130 N-[(15Z)-tetracosenoyl]sphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74130 CHEBI:74132 N-[(17Z)-hexacosenoyl]sphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74132 CHEBI:74134 (17Z)-hexacosenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74134 CHEBI:74133 (15Z)-3-oxotetracosenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74133 CHEBI:74149 (17Z)-hexacosenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74149 CHEBI:74148 2-hydroxybehenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74148 GO:0052803 imidazole-containing compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052803 imidazole metabolism The chemical reactions and pathways involving imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton. GO:0052802 nitroimidazole metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052802 nitroimidazole metabolism The chemical reactions and pathways involving nitroimidazoles, imidazole derivatives with a nitro group attached to one ring. GO:0052801 bicyclic nitroimidazole metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052801 bicyclic nitroimidazole metabolism The chemical reactions and pathways involving bicyclic nitroimidazoles, imidazole derivatives with two rings and a nitro group attached to one ring. GO:0052800 bicyclic nitroimidazole catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052800 bicyclic nitroimidazole breakdown|bicyclic nitroimidazole catabolism|bicyclic nitroimidazole degradation The chemical reactions and pathways resulting in the breakdown of a bicyclic nitroimidazole. GO:0052807 aflatoxin reductase (coenzyme F420) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052807 coenzyme F420-dependent aflatoxin reductase activity|coenzyme F420-aflatoxin reductase activity|aflatoxin:coenzyme F420 oxidoreductase activity|aflatoxin:reduced coenzyme F420 reductase activity Catalysis of the reaction: aflatoxin + 1,5-dihydrocoenzyme F420 = aflatoxin with reduced furanocoumarin moiety + coenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420. GO:0052806 sulfite reductase (coenzyme F420) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052806 coenzyme F420-dependent sulfite reductase activity|coenzyme F420-sulfite reductase activity|sulfite:reduced coenzyme F420 reductase activity|hydrogen-sulfide:coenzyme F420 oxidoreductase activity Catalysis of the reaction: sulfite + 3 1,5-dihydrocoenzyme F420 = hydrogen sulfide + 3 H2O + 3 coenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420. GO:0052805 imidazole-containing compound catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052805 imidazole catabolism|imidazole degradation|imidazole breakdown The chemical reactions and pathways resulting in the breakdown of imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton. GO:0052804 nitroimidazole catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052804 nitroimidazole degradation|nitroimidazole breakdown|nitroimidazole catabolism The chemical reactions and pathways resulting in the breakdown of nitroimidazoles, imidazole derivatives with a nitro group attached to one ring. GO:0052809 acharan sulfate lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052809 Catalysis of the cleavage of a carbon-oxygen bond in acharan sulfate, a glycosaminoglycan with a uniformly repeating disaccharide structure of alpha-D-N-acetylglucosaminyl-2-O-sulfo-alpha-L-iduronic acid. GO:0052808 reduced coenzyme F420:NADP+ oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052808 EC:1.5.1.40 F420H2:NADP oxidoreductase activity|NADP+:F420 oxidoreductase activity|coenzyme F420-dependent NADP oxidoreductase activity|coenzyme F420-dependent NADP reductase activity|F420H2:NADP+ oxidoreductase activity Catalysis of the reaction: NADP+ + 1,5-dihydrocoenzyme F420 = NADPH + H+ + coenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420. UBERON:0022292 splenic arteriole biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0022292 UBERON:0022293 reproductive gland secretion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0022293 genital fluid|reproductive system secretion|reproductive system fluid/secretion|genital secretion|reproductive system fluid A portion of organism substance that is secreted by a reproductive gland. CHEBI:74141 montanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74141 CHEBI:74140 2-hydroxytetracosanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74140 CHEBI:74143 dTDP-6-deoxy-alpha-D-allose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74143 CHEBI:74142 (15Z)-tetracosenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74142 CHEBI:74146 C24:1-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74146 GO:0052810 1-phosphatidylinositol-5-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052810 Reactome:R-HSA-1675810|Reactome:R-HSA-1675866|RHEA:44680 ATP:1-phosphatidyl-1D-myo-inositol 5-phosphotransferase activity|1-phosphatidylinositol 5-kinase activity Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 5-phosphate + ADP + 2 H(+). CHEBI:74159 D-cycloserine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74159 GO:0052814 medium-chain-aldehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052814 EC:1.2.1.- medium-chain-aldehyde:NAD+ oxidoreductase activity|medium-chain aliphatic aldehyde dehydrogenase activity|medium-chain fatty aldehyde dehydrogenase activity Catalysis of the reaction: a medium-chain aldehyde + NAD+ = a medium-chain carboxylate + NADH + H+. Medium-chain aldehydes have a chain length of between 8 and 12 carbons. GO:0052813 phosphatidylinositol bisphosphate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052813 Catalysis of the reaction: ATP + a phosphatidylinositol bisphosphate = ADP + a phosphatidylinositol trisphosphate. GO:0052812 phosphatidylinositol-3,4-bisphosphate 5-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052812 Reactome:R-HSA-1675773|EC:2.7.1.153 ATP:1-phosphatidyl-1D-myo-inositol-3,4-bisphosphate 5-phosphotransferase activity Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + ADP + 2 H(+). GO:0052811 1-phosphatidylinositol-3-phosphate 4-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052811 RHEA:63688|Reactome:R-HSA-1676145 phosphatidylinositol 3-phosphate 4-kinase activity|ATP:1-phosphatidyl-1D-myo-inositol-3-phosphate 4-phosphotransferase activity Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ADP + 2 H(+). GO:0052818 heteroglycan 3-alpha-mannosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052818 EC:2.4.1.48|MetaCyc:RXN-7992|KEGG_REACTION:R03769 GDP-mannose:heteroglycan 3-alpha-D-mannosyltransferase activity|heteropolysaccharide 3-alpha-mannosyltransferase activity|guanosine diphosphomannose-heteroglycan 3-alpha-mannosyltransferase activity|GDP mannose 3-alpha-mannosyltransferase activity Catalysis of the reaction: heteroglycan + GDP-mannose = (1->3)-alpha-D-mannosylheteroglycan + GDP. GO:0052817 very long chain acyl-CoA hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052817 very long-chain acyl-thioester hydrolase activity|very long-chain-acyl-CoA hydrolase activity|very long-chain acyl coenzyme A hydrolase activity|very long-chain hydrolase activity Catalysis of the reaction: H2O + a very long chain acyl-CoA = a very long chain carboxylate + CoA. A very long chain has chain length greater than C18. GO:0052816 long-chain acyl-CoA hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052816 long-chain acyl coenzyme A hydrolase activity|long-chain hydrolase activity|long-chain acyl-thioester hydrolase activity|long-chain-acyl-CoA hydrolase activity Catalysis of the reaction: H2O + a long-chain acyl-CoA = a long-chain carboxylate + CoA. A long chain is a chain of greater than 12 carbons in length. GO:0052815 medium-chain acyl-CoA hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052815 medium-chain acyl coenzyme A hydrolase activity|medium-chain-acyl-CoA hydrolase activity|medium-chain hydrolase activity|medium-chain acyl-thioester hydrolase activity Catalysis of the reaction: H2O + a medium-chain acyl-CoA = a medium-chain carboxylate + CoA. A medium chain is a chain of between eight and twelve carbons in length. GO:0052819 heteroglycan 2-alpha-mannosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052819 KEGG_REACTION:R03768|MetaCyc:2.4.1.48-RXN|EC:2.4.1.48 GDP-mannose:heteroglycan 2-alpha-D-mannosyltransferase activity|heteropolysaccharide 2-alpha-mannosyltransferase activity|guanosine diphosphomannose-heteroglycan 2-alpha-mannosyltransferase activity|GDP mannose 2-alpha-mannosyltransferase activity Catalysis of the reaction: heteroglycan + GDP-mannose = (1->2)-alpha-D-mannosylheteroglycan + GDP. CHEBI:74150 octacosanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74150 CHEBI:74151 S-palmitoyl-L-cysteine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74151 CHEBI:74153 dTDP-5,5-di-C-methyl-beta-L-lyxose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74153 CHEBI:74156 3-amino-4,7-dihydroxycoumarin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74156 CHEBI:74155 3-dimethylallyl-4-hydroxybenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74155 CHEBI:74158 O-ureido-D-serine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74158 GO:0052821 DNA-7-methyladenine glycosylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052821 EC:3.2.2.21|MetaCyc:3.2.2.21-RXN Catalysis of the reaction: DNA containing 7-methyladenine + H2O = DNA with abasic site + 7-methyladenine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 7-methyladenine and the deoxyribose sugar to remove the 7-methyladenine, leaving an abasic site. GO:0052820 DNA-1,N6-ethenoadenine N-glycosylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052820 1,N6-ethenoadenine glycosylase activity|1,N(6)-ethenoadenine N-glycosylase activity Catalysis of the reaction: DNA with 1-N6-ethenoadenine + H2O = DNA with abasic site + 1-N6-ethenoadenine. This reaction is the removal of 1,N6-ethenoadenine by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. GO:0052825 inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052825 Reactome:R-HSA-1855219 Catalysis of the reaction: inositol-1,3,4,5,6-pentakisphosphate + H2O = inositol-3,4,5,6-tetrakisphosphate + phosphate. GO:0052824 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052824 GO:0052823 2-hydroxy-6-oxonona-2,4,7-trienedioate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052823 MetaCyc:RXN-12070|UM-BBD_reactionID:r1622|EC:3.7.1.14|RHEA:25046 2-hydroxy-6-ketonona-2,4,7-trienedoic acid hydrolase activity|(2E,4Z,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioate fumarylhydrolase activity Catalysis of the reaction: (2E,4Z,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioate + H2O = (2E)-2-hydroxypenta-2,4-dienoate + fumarate + H+. GO:0052822 DNA-3-methylguanine glycosylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052822 EC:3.2.2.21|MetaCyc:3.2.2.21-RXN 3-methylguanine DNA glycosylase I|deoxyribonucleate 3-methylguanine glycosidase I|DNA glycosidase I activity|alkylated-DNA glycohydrolase (releasing methyladenine and methylguanine) Catalysis of the reaction: DNA containing 3-methylguanine + H2O = DNA with abasic site + 3-methylguanine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methylguanine and the deoxyribose sugar to remove the 3-methylguanine, leaving an abasic site. GO:0052829 inositol-1,3,4-trisphosphate 1-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052829 Reactome:R-HSA-1855232 Catalysis of the reaction: D-myo-inositol 1,3,4-trisphosphate + H2O = myo-inositol 3,4-bisphosphate + phosphate. GO:0052828 inositol-3,4-bisphosphate 4-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052828 Reactome:R-HSA-1855202|RHEA:43388 Catalysis of the reaction: 1D-myo-inositol 3,4-bisphosphate + H2O = 1D-myo-inositol 3-phosphate + phosphate. GO:0052827 inositol pentakisphosphate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052827 Catalysis of the reaction: myo-inositol pentakisphosphate + H2O = myo-inositol tetrakisphosphate + phosphate. GO:0052826 inositol hexakisphosphate 2-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052826 EC:3.1.3.62|Reactome:R-HSA-1855225 1D-myo-inositol-hexakisphosphate 2-phosphohydrolase activity Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = myo-inositol 1,3,4,5,6-pentakisphosphate + phosphate. CHEBI:74161 C26:1-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74161 CHEBI:74160 C24:1-sphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74160 CHEBI:74162 C26:1-sphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74162 CHEBI:74165 (E)-1,3-pentadiene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74165 CHEBI:74164 nitrocyclohexane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74164 CHEBI:74167 N-tetracosanoyl-C17-sphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74167 CHEBI:74166 C17 sphingosine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74166 CHEBI:74169 L-alaninamide(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74169 CHEBI:74168 D-ribono-1,4-lactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74168 GO:0052832 inositol monophosphate 3-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052832 Reactome:R-HSA-1855210|RHEA:30739|EC:3.1.3.25|MetaCyc:MYO-INOSITOL-1OR-4-MONOPHOSPHATASE-RXN Catalysis of the reaction: myo-inositol 3-phosphate + H2O = myo-inositol + phosphate. GO:0052831 inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052831 Reactome:R-HSA-1855159 Catalysis of the reaction: inositol-1,3,4,6-tetrakisphosphate + H2O = inositol-3,4,6-trisphosphate + phosphate. GO:0052830 inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052830 Reactome:R-HSA-1855171 Catalysis of the reaction: inositol-1,3,4,6-tetrakisphosphate + H2O = inositol-1,3,4-trisphosphate + phosphate. GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052836 Reactome:R-HSA-1855158|Reactome:R-HSA-1855224 Catalysis of the reaction: ATP + inositol 5-diphosphate pentakisphosphate = ADP + inositol 5-triphosphate pentakisphosphate. GO:0052835 inositol-3,4,6-trisphosphate 1-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052835 Reactome:R-HSA-1855169|EC:2.7.1.- 1D-myo-inositol-trisphosphate 1-kinase activity|ATP:1D-myo-inositol-3,4,6-trisphosphate 1-phosphotransferase activity|inositol-trisphosphate 1-kinase activity|ins(3,4,6)P(3) 1-kinase activity|IP3 1-kinase activity|Ins(3,4,6)P3 1-kinase activity|inositol 3,4,6-trisphosphate 1-kinase activity Catalysis of the reaction: 1D-myo-inositol 3,4,6-trisphosphate + ATP = 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ADP + 2 H(+). GO:0052834 inositol monophosphate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052834 MetaCyc:RXN-10949|RHEA:24056|EC:3.1.3.25 inositol-1(or 4)-monophosphatase activity|myo-inositol monophosphatase activity|myo-inositol phosphatase activity|myo-inositol-1(or 4)-phosphate phosphohydrolase activity|inositol-phosphate phosphatase activity|myo-inositol-phosphate phosphohydrolase activity|L-myo-inositol-phosphate phosphatase activity|myo-inositol-phosphatase activity|inositol phosphatase activity Catalysis of the reaction: myo-inositol phosphate + H2O = myo-inositol + phosphate. GO:0052833 inositol monophosphate 4-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052833 Reactome:R-HSA-1855211|MetaCyc:RXN-10952|RHEA:30735|EC:3.1.3.25 inositol-1(or 4)-monophosphatase activity|myo-inositol-1(or 4)-phosphate phosphohydrolase activity|myo-inositol-1(or 4)-monophosphatase activity Catalysis of the reaction: myo-inositol 4-phosphate + H2O = myo-inositol + phosphate. GO:0052839 inositol diphosphate tetrakisphosphate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052839 Reactome:R-HSA-1855230|Reactome:R-HSA-1855193 Catalysis of the reaction: Catalysis of the reaction: ATP + inositol diphosphate tetrakisphosphate = ADP + inositol bisdiphosphate trisphosphate. GO:0052838 thiazole metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052838 thiazole metabolism The chemical reactions and pathways involving thiazole, a five-membered heterocyclic ring structure containing a sulfur in the 1-position and a nitrogen in the 3-position. GO:0052837 thiazole biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052837 thiazole formation|thiazole biosynthesis|thiazole anabolism|thiazole synthesis The chemical reactions and pathways resulting in the formation of a thiazole, a five-membered heterocyclic ring structure containing a sulfur in the 1-position and a nitrogen in the 3-position. CHEBI:15768 3,5-diiodo-L-tyrosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15768 CHEBI:64702 nucleotide-sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64702 CHEBI:15767 dichloromethane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15767 CHEBI:15769 N-[(R)-4-phosphopantothenoyl]-L-cysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15769 CHEBI:15764 anthocyanidin 3,5-diglucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15764 CHEBI:64705 aspyridone B biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64705 CHEBI:15763 nicotinic acid D-ribonucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15763 CHEBI:15766 N-benzoyl-D-arginine-4-nitroanilide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15766 CHEBI:39737 D-sorbose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39737 CHEBI:64704 aspyridone A biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64704 CHEBI:15765 L-dopa biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15765 CHEBI:15760 tyramine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15760 CHEBI:64709 organic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64709 CHEBI:64708 one-carbon compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64708 CHEBI:15761 N-methylpyridinium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15761 CHEBI:25105 macrolide antibiotic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25105 CHEBI:25108 magnesium molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25108 CHEBI:25107 magnesium atom biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_25107 CHEBI:25106 macrolide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25106 CHEBI:15757 (S)-4-amino-5-oxopentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15757 CHEBI:64712 trivalent inorganic cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64712 CHEBI:39745 dihydrogenphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39745 CHEBI:15756 hexadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15756 CHEBI:64711 purine nucleotide-sugar biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64711 CHEBI:15759 2,3-epoxyphylloquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15759 CHEBI:15758 leucocyanidin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15758 CHEBI:64717 sn-glycero-3-phospho-(1'-sn-glycerol)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64717 CHEBI:15753 2-oxoadipic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15753 CHEBI:64716 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64716 CHEBI:15755 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15755 CHEBI:15754 3-O-beta-D-galactopyranosyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15754 CHEBI:40721 adenosine 5'-monophosphate(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_40721 CHEBI:64719 L-argininiumyl(2+) group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64719 CHEBI:15751 ADP alpha-D-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15751 CHEBI:64718 L-alaniniumyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64718 CHEBI:15750 dolichyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15750 CHEBI:40729 N-acetyl-beta-D-muramic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_40729 CHEBI:64720 L-alpha-aspartyl zwitterionic group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64720 CHEBI:64723 glyciniumyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64723 CHEBI:15789 2'-O-methyllicodione biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15789 CHEBI:64722 L-glutaminiumyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64722 CHEBI:64721 L-alpha-glutamyl zwitterionic group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64721 CHEBI:15786 3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15786 CHEBI:15785 1-(alk-1-enyl)-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15785 CHEBI:15788 3,5-dichlorocatechol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15788 CHEBI:64726 thioselenide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64726 CHEBI:15787 deoxylimonoic acid D-ring-lactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15787 CHEBI:15782 viomycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15782 CHEBI:15781 N(alpha),N(alpha),N(alpha)-trimethyl-L-histidine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15781 CHEBI:15784 N-acetyl-D-glucosamine 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15784 CHEBI:64729 glutathioselenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64729 CHEBI:15783 N,N-dimethyl-1,4-phenylenediamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15783 CHEBI:64731 L-methioniniumyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64731 CHEBI:15779 N-acyl-D-aspartic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15779 CHEBI:15778 N-acyl-D-amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15778 CHEBI:64739 L-threoniniumyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64739 CHEBI:15775 3-oxoadipate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15775 CHEBI:64738 L-seriniumyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64738 CHEBI:15774 dTDP-beta-L-rhamnose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15774 CHEBI:15777 4-oxocyclohexanecarboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15777 CHEBI:15776 cephalosporin C biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15776 UBERON:2000648 dorsal fin musculature biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_2000648 Musculature that is part of the dorsal fin. CHEBI:15771 loganin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15771 CHEBI:15770 D-erythritol 4-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15770 CHEBI:15773 cyclohexylamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15773 CHEBI:15772 L-dopachrome biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15772 CHEBI:15728 4-guanidinobutanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15728 CHEBI:64742 L-asparaginiumyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64742 CHEBI:15727 carnosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15727 CHEBI:64741 L-valiniumyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64741 CHEBI:15729 L-ornithine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15729 CHEBI:15724 trimethylamine N-oxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15724 CHEBI:15723 1,6-bis-O-galloyl-beta-D-glucose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15723 CHEBI:64745 phytochelatin 3 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64745 CHEBI:64744 phytochelatin 2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64744 CHEBI:15726 1-acyl-2-linoleoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15726 CHEBI:64743 2-monolysocardiolipin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64743 CHEBI:15725 trimethylenediamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15725 CHEBI:15720 8-[(1R,2R)-3-oxo-2-{(Z)-pent-2-en-1-yl}cyclopentyl]octanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15720 CHEBI:64747 phytochelatin 4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64747 CHEBI:15721 sedoheptulose 7-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15721 CHEBI:15717 4beta-(hydroxymethyl)-4alpha-methyl-5alpha-cholest-7-en-3beta-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15717 CHEBI:15716 12-hydroxydihydrochelirubine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15716 CHEBI:15718 2,3',4,6-tetrahydroxybenzophenone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15718 CHEBI:15713 UTP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15713 CHEBI:64757 3-palmitoyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64757 CHEBI:15712 2,3-dihydrobiochanin A biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15712 CHEBI:64755 EDTA(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64755 CHEBI:15715 streptomycin 3''-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15715 CHEBI:15714 trans-sinapic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15714 CHEBI:15711 1D-1-O-(indol-3-yl)acetyl-myo-inositol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15711 CHEBI:15710 betaine aldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15710 CHEBI:64760 3-acyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64760 CHEBI:64763 EC 3.1.4.11 (phosphoinositide phospholipase C) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64763 CHEBI:15749 3-carboxy-cis,cis-muconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15749 CHEBI:15746 spermine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15746 CHEBI:64768 zwitterionic group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64768 CHEBI:64767 anionic group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64767 CHEBI:15745 2-aminomuconic 6-semialdehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15745 CHEBI:15748 D-glucuronate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15748 CHEBI:64766 cationic group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64766 CHEBI:64765 sn-glycero-3-phosphoserine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64765 CHEBI:15742 pseudotropine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15742 CHEBI:15741 succinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15741 CHEBI:64769 organic cationic group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64769 CHEBI:15743 butanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15743 UBERON:0022351 parietal serous membrane biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0022351 cavity lining|parietal wall of serous membrane Serous membrane layer that lines to a body cavity. UBERON:0022350 visceral serous membrane biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0022350 visceral wall of serous membrane Serous membrane layer that is adjacent to and lines an organ. CHEBI:15740 formate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15740 OBO:chebi#is_conjugate_base_of is conjugate base of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of UBERON:0022355 basal layer of endometrium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0022355 stratum basalis of endometrium|pars basalis of endometrium The layer of endometrial epithelium adjacent to the uterine cavity. UBERON:0022358 placenta blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0022358 placental vessel A blood vessel of the placenta. CHEBI:64771 1-acyl-sn-glycero-3-phospho-1D-myo-inositol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64771 CHEBI:15739 isopropylamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15739 CHEBI:64775 organic anionic group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64775 CHEBI:15738 staurosporine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15738 CHEBI:15735 S-formylmycothiol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15735 CHEBI:15734 primary alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15734 CHEBI:15737 N-carbamoylsarcosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15737 CHEBI:64776 inorganic anionic group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64776 CHEBI:15730 pyruvic oxime biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15730 UBERON:0022360 male mammary gland duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0022360 A mammary gland duct that is part of a male organism. This structure typically regresses. CHEBI:15733 N-methylaniline biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15733 CHEBI:15732 phosphonoacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15732 UBERON:0022361 lung field biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0022361 lung field A specific region of the foregut into the area in which the lung will develop. CHEBI:25179 melanins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25179 CHEBI:25174 mannooligosaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25174 GO:1904559 cellular response to dextromethorphan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904559 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dextromethorphan stimulus. GO:1904558 response to dextromethorphan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904558 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dextromethorphan stimulus. GO:1904557 L-alanine transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904557 The directed movement of L-alanine across a membrane. CHEBI:25171 mannosyl groups biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25171 GO:1904556 L-tryptophan transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904556 The directed movement of L-tryptophan across a membrane. GO:1904555 L-proline transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904555 The directed movement of L-proline across a membrane. CHEBI:25176 mannuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25176 GO:1904554 positive regulation of chemotaxis to arachidonic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904554 up regulation of chemotaxis to arachidonic acid|upregulation of chemotaxis to arachidonic acid|up-regulation of chemotaxis to arachidonic acid|activation of chemotaxis to arachidonic acid Any process that activates or increases the frequency, rate or extent of chemotaxis to arachidonic acid. GO:1904553 negative regulation of chemotaxis to arachidonic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904553 down-regulation of chemotaxis to arachidonic acid|downregulation of chemotaxis to arachidonic acid|down regulation of chemotaxis to arachidonic acid|inhibition of chemotaxis to arachidonic acid Any process that stops, prevents or reduces the frequency, rate or extent of chemotaxis to arachidonic acid. CHEBI:25175 mannuronates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25175 GO:1904563 phosphatidylinositol 5-phosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904563 phosphatidylinositol 5-phosphate formation|phosphatidylinositol 5-phosphate anabolism|phosphatidylinositol 5-phosphate biosynthesis|phosphatidylinositol 5-phosphate synthesis The chemical reactions and pathways resulting in the formation of phosphatidylinositol 5-phosphate. GO:1904562 phosphatidylinositol 5-phosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904562 phosphatidylinositol 5-phosphate metabolism The chemical reactions and pathways involving phosphatidylinositol 5-phosphate. UBERON:0036925 wall of eyeball biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036925 eyeball wall GO:1904561 cellular response to diphenidol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904561 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diphenidol stimulus. GO:1904560 response to diphenidol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904560 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diphenidol stimulus. CHEBI:50130 monacolin L biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50130 CHEBI:50127 trifluoromethyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50127 CHEBI:50126 tetrasaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50126 CHEBI:50129 2-hydroxyisobutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50129 CHEBI:25185 menaquinones biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_25185 CHEBI:132416 O(3)-(N-acetyl-alpha-D-glucosaminyl-poly[(1->4)-beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl]-(1->4)-beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-serine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132416 CHEBI:132415 O(3)-(poly[(1->4)-beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl]-(1->4)-beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-serine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132415 GO:1904569 regulation of selenocysteine incorporation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904569 Any process that modulates the frequency, rate or extent of selenocysteine incorporation. GO:1904568 cellular response to wortmannin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904568 cellular response to wartmannin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a wortmannin stimulus. GO:1904567 response to wortmannin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904567 response to wartmannin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a wortmannin stimulus. CHEBI:25189 1,4-dimercaptobutane-2,3-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_25189 GO:1904566 cellular response to 1-oleoyl-sn-glycerol 3-phosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904566 cellular response to oleoyl lysophosphatidic acid|cellular response to 1-oleoyl lysophosphatidic acid|cellular response to LPA|cellular response to lysophosphatidic acid|cellular response to oleoyl-L-alpha-lysophosphatidic acid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-oleoyl-sn-glycerol 3-phosphate stimulus. GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904565 response to oleoyl-L-alpha-lysophosphatidic acid|response to oleoyl lysophosphatidic acid|response to LPA|response to 1-oleoyl lysophosphatidic acid|response to lysophosphatidic acid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-oleoyl-sn-glycerol 3-phosphate stimulus. CHEBI:25187 p-menthan-3-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_25187 GO:1904564 Nbp35-Cfd1 ATPase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1904564 IntAct:EBI-11666137 An iron-sulfur cluster assembly complex that is capable of weak ATPase activity. In yeast it consists of two subunits, Nbp35 and Cfd1. CHEBI:25186 p-menthane monoterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25186 GO:1904574 negative regulation of selenocysteine insertion sequence binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904574 downregulation of SECIS binding|down regulation of selenocysteine insertion sequence binding|downregulation of selenocysteine insertion sequence binding|negative regulation of SECIS binding|down-regulation of SECIS binding|inhibition of SECIS binding|down-regulation of selenocysteine insertion sequence binding|inhibition of selenocysteine insertion sequence binding|down regulation of SECIS binding Any process that stops, prevents or reduces the frequency, rate or extent of selenocysteine insertion sequence binding. GO:1904573 regulation of selenocysteine insertion sequence binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904573 regulation of SECIS binding Any process that modulates the frequency, rate or extent of selenocysteine insertion sequence binding. GO:1904572 negative regulation of mRNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904572 down-regulation of mRNA binding|downregulation of mRNA binding|down regulation of mRNA binding|inhibition of mRNA binding Any process that stops, prevents or reduces the frequency, rate or extent of mRNA binding. GO:1904571 positive regulation of selenocysteine incorporation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904571 up-regulation of selenocysteine incorporation|activation of selenocysteine incorporation|up regulation of selenocysteine incorporation|upregulation of selenocysteine incorporation Any process that activates or increases the frequency, rate or extent of selenocysteine incorporation. GO:1904570 negative regulation of selenocysteine incorporation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904570 down-regulation of selenocysteine incorporation|downregulation of selenocysteine incorporation|down regulation of selenocysteine incorporation|inhibition of selenocysteine incorporation Any process that stops, prevents or reduces the frequency, rate or extent of selenocysteine incorporation. CHEBI:50121 1,2-thiazolidine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50121 CHEBI:50116 4-hydroxy-3-octaprenylbenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50116 UBERON:0022303 nervous system cell part layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0022303 layer|lamina Single layer of a laminar structure, identified by different density, arrangement or size of cells and processes arranged in flattened layers or lamina[CUMBO]. CHEBI:50115 hyponitrite(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50115 CHEBI:50114 estrogen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50114 CHEBI:50113 androgen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50113 CHEBI:50118 (6aS,11aS)-2-dimethylallyl-3,6a,9-trihydroxypterocarpan biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50118 CHEBI:50117 phenylglyoxylyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50117 CHEBI:25150 prunasin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_25150 GO:1904579 cellular response to thapsigargin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904579 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thapsigargin stimulus. GO:1904578 response to thapsigargin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904578 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thapsigargin stimulus. CHEBI:25155 manganese cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25155 GO:1904577 cellular response to tunicamycin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904577 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tunicamycin stimulus. CHEBI:25154 manganese molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25154 GO:1904576 response to tunicamycin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904576 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tunicamycin stimulus. CHEBI:49125 N-(beta-D-glucosyl)nicotinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49125 GO:1904575 positive regulation of selenocysteine insertion sequence binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904575 upregulation of selenocysteine insertion sequence binding|up regulation of SECIS binding|activation of SECIS binding|positive regulation of SECIS binding|up regulation of selenocysteine insertion sequence binding|activation of selenocysteine insertion sequence binding|up-regulation of SECIS binding|up-regulation of selenocysteine insertion sequence binding|upregulation of SECIS binding Any process that activates or increases the frequency, rate or extent of selenocysteine insertion sequence binding. CHEBI:49124 N-(beta-D-glucosyl)nicotinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49124 GO:1904585 response to putrescine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904585 response to tetramethylenediamine|response to 1,4-Butanediamine|response to 1,4-Diaminobutane Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a putrescine stimulus. GO:1904584 cellular response to polyamine macromolecule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904584 cellular response to polyamines|cellular response to polyamine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polyamine macromolecule stimulus. GO:1904583 response to polyamine macromolecule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904583 response to polyamine|response to polyamines Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polyamine macromolecule stimulus. GO:1904582 positive regulation of intracellular mRNA localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904582 up regulation of intracellular mRNA localisation|up-regulation of mRNA localization, intracellular|activation of mRNA localization, intracellular|positive regulation of intracellular mRNA localisation|activation of intracellular mRNA localisation|up-regulation of intracellular mRNA positioning|up-regulation of establishment and maintenance of intracellular RNA localization|up regulation of intracellular mRNA localization|up regulation of mRNA positioning, intracellular|activation of intracellular mRNA localization|positive regulation of mRNA positioning, intracellular|activation of intracellular mRNA positioning|positive regulation of mRNA localization, intracellular|up-regulation of intracellular mRNA localisation|up regulation of mRNA localization, intracellular|activation of mRNA positioning, intracellular|positive regulation of intracellular mRNA positioning|upregulation of establishment and maintenance of intracellular RNA localization|up regulation of intracellular mRNA positioning|up-regulation of intracellular mRNA localization|up-regulation of mRNA positioning, intracellular|upregulation of intracellular mRNA localisation|upregulation of mRNA localization, intracellular|up regulation of establishment and maintenance of intracellular RNA localization|positive regulation of establishment and maintenance of intracellular RNA localization|activation of establishment and maintenance of intracellular RNA localization|upregulation of intracellular mRNA positioning|upregulation of intracellular mRNA localization|upregulation of mRNA positioning, intracellular Any process that activates or increases the frequency, rate or extent of intracellular mRNA localization. GO:1904581 negative regulation of intracellular mRNA localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904581 inhibition of intracellular mRNA positioning|down-regulation of establishment and maintenance of intracellular RNA localization|down regulation of mRNA positioning, intracellular|down regulation of intracellular mRNA localization|negative regulation of establishment and maintenance of intracellular RNA localization|downregulation of intracellular mRNA localization|downregulation of mRNA positioning, intracellular|down-regulation of intracellular mRNA localisation|negative regulation of intracellular mRNA localisation|inhibition of establishment and maintenance of intracellular RNA localization|down-regulation of mRNA localization, intracellular|negative regulation of mRNA localization, intracellular|down-regulation of intracellular mRNA positioning|negative regulation of intracellular mRNA positioning|inhibition of intracellular mRNA localisation|negative regulation of mRNA positioning, intracellular|down-regulation of intracellular mRNA localization|down-regulation of mRNA positioning, intracellular|downregulation of mRNA localization, intracellular|inhibition of intracellular mRNA localization|down regulation of establishment and maintenance of intracellular RNA localization|down regulation of mRNA localization, intracellular|downregulation of intracellular mRNA positioning|inhibition of mRNA localization, intracellular|downregulation of establishment and maintenance of intracellular RNA localization|down regulation of intracellular mRNA positioning|down regulation of intracellular mRNA localisation|inhibition of mRNA positioning, intracellular|downregulation of intracellular mRNA localisation Any process that stops, prevents or reduces the frequency, rate or extent of intracellular mRNA localization. GO:1904580 regulation of intracellular mRNA localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904580 regulation of mRNA positioning, intracellular|regulation of mRNA localization, intracellular|regulation of establishment and maintenance of intracellular RNA localization|regulation of intracellular mRNA positioning|regulation of intracellular mRNA localisation Any process that modulates the frequency, rate or extent of intracellular mRNA localization. CHEBI:40799 androsta-1,4-diene-3,17-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_40799 CHEBI:50112 sex hormone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50112 CHEBI:50111 deoxycholoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50111 CHEBI:50110 isopiperitenone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50110 UBERON:0022317 olfactory cortex layer 1 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0022317 layer 1 of olfactory cortex|olfactory cortex plexiform layer Surface layer of the olfactory cortex that contains dendrites, fiber systems and a small number of neurons. It has been divided into a superficial part and a deep part. CHEBI:25169 mannoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25169 CHEBI:50103 excitatory amino acid agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50103 CHEBI:25168 mannosylinositol phosphorylceramide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25168 CHEBI:50109 3alpha,7alpha,12alpha-trihydroxy-5alpha-cholan-24-yl sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50109 UBERON:0022318 olfactory cortex layer 2 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0022318 layer 2 of olfactory cortex Middle layer of olfactory cortex lying deep to layer 1 and superficial to layer 3, characterized by a compact layer of cell bodies. It can be divided into a superficial part and a deep part. CHEBI:50108 5alpha-cholane-3alpha,7alpha,12alpha,24-tetrol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50108 CHEBI:50107 5beta-scymnol sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50107 CHEBI:50106 5beta-scymnol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50106 CHEBI:49110 peripheral nervous system drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49110 GO:1904589 regulation of protein import biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904589 regulation of protein uptake Any process that modulates the frequency, rate or extent of protein import. CHEBI:25167 mannosaminolactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25167 GO:1904588 cellular response to glycoprotein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904588 cellular response to glycoproteins Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus. CHEBI:25166 mannosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25166 GO:1904587 response to glycoprotein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904587 response to glycoproteins Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus. CHEBI:25165 mannosamine phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25165 GO:1904586 cellular response to putrescine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904586 cellular response to tetramethylenediamine|cellular response to 1,4-Butanediamine|cellular response to 1,4-Diaminobutane Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a putrescine stimulus. GO:1904596 regulation of connective tissue replacement involved in inflammatory response wound healing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904596 regulation of fibrosis during inflammatory response|regulation of connective tissue replacement during inflammatory response Any process that modulates the frequency, rate or extent of connective tissue replacement involved in inflammatory response wound healing. GO:1904595 positive regulation of termination of RNA polymerase II transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904595 upregulation of RNA polymerase II transcription termination|up regulation of transcription termination from RNA polymerase II promoter|activation of transcription termination from RNA polymerase II promoter|up-regulation of RNA 3'-end formation by RNA polymerase II|positive regulation of transcription termination from RNA polymerase II promoter|upregulation of RNA polymerase II transcription termination factor activity|upregulation of transcription termination from Pol II promoter|up regulation of RNA polymerase II transcription termination|up regulation of termination of RNA polymerase II transcription|activation of RNA polymerase II transcription termination|positive regulation of RNA polymerase II transcription termination|upregulation of RNA 3'-end formation by RNA polymerase II|up regulation of RNA polymerase II transcription termination factor activity|up-regulation of transcription termination from RNA polymerase II promoter|up-regulation of transcription termination from Pol II promoter|positive regulation of RNA polymerase II transcription termination factor activity|activation of transcription termination from Pol II promoter|upregulation of termination of RNA polymerase II transcription|activation of RNA polymerase II transcription termination factor activity|up regulation of RNA 3'-end formation by RNA polymerase II|up-regulation of RNA polymerase II transcription termination|upregulation of transcription termination from RNA polymerase II promoter|activation of RNA 3'-end formation by RNA polymerase II|positive regulation of RNA 3'-end formation by RNA polymerase II|positive regulation of transcription termination from Pol II promoter|up-regulation of RNA polymerase II transcription termination factor activity|up regulation of transcription termination from Pol II promoter|up-regulation of termination of RNA polymerase II transcription|activation of termination of RNA polymerase II transcription Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase II transcription. GO:1904594 regulation of termination of RNA polymerase II transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904594 regulation of transcription termination from Pol II promoter|regulation of RNA polymerase II transcription termination|regulation of RNA polymerase II transcription termination factor activity|regulation of RNA 3'-end formation by RNA polymerase II|regulation of transcription termination from RNA polymerase II promoter Any process that modulates the frequency, rate or extent of termination of RNA polymerase II transcription. GO:1904593 prostaglandin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1904593 Interacting selectively and non-covalently with prostaglandin. GO:1904592 positive regulation of protein refolding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904592 upregulation of heat shock protein activity|upregulation of protein refolding|up regulation of heat shock protein activity|positive regulation of heat shock protein activity|up regulation of protein refolding|activation of protein refolding|activation of heat shock protein activity|up-regulation of heat shock protein activity|up-regulation of protein refolding Any process that activates or increases the frequency, rate or extent of protein refolding. GO:1904591 positive regulation of protein import biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904591 up-regulation of protein import|activation of protein import|up-regulation of protein uptake|activation of protein uptake|up regulation of protein import|positive regulation of protein uptake|up regulation of protein uptake|upregulation of protein import|upregulation of protein uptake Any process that activates or increases the frequency, rate or extent of protein import. GO:1904590 negative regulation of protein import biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904590 down-regulation of protein import|down-regulation of protein uptake|negative regulation of protein uptake|downregulation of protein import|downregulation of protein uptake|down regulation of protein import|inhibition of protein import|down regulation of protein uptake|inhibition of protein uptake Any process that stops, prevents or reduces the frequency, rate or extent of protein import. UBERON:0022320 dorsal cochlear nucleus pyramidal cell layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0022320 CHEBI:49104 heteroarenecarbaldehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49104 CHEBI:49107 thiamine(2+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49107 CHEBI:25136 malonyl-CoAs biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25136 CHEBI:49106 oxepane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49106 CHEBI:49109 D-dopachrome biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49109 CHEBI:49108 dopachrome biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49108 CHEBI:49101 N-(3,4-dichlorophenyl)malonamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49101 GO:1904599 advanced glycation end-product binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1904599 Interacting selectively and non-covalently with advanced glycation end-product. CHEBI:49100 adenosylcobalamin 5'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49100 GO:1904598 positive regulation of connective tissue replacement involved in inflammatory response wound healing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904598 activation of connective tissue replacement during inflammatory response|up-regulation of connective tissue replacement involved in inflammatory response wound healing|up regulation of fibrosis during inflammatory response|positive regulation of connective tissue replacement during inflammatory response|positive regulation of fibrosis during inflammatory response|up regulation of connective tissue replacement during inflammatory response|activation of fibrosis during inflammatory response|upregulation of connective tissue replacement involved in inflammatory response wound healing|up-regulation of fibrosis during inflammatory response|upregulation of connective tissue replacement during inflammatory response|up regulation of connective tissue replacement involved in inflammatory response wound healing|activation of connective tissue replacement involved in inflammatory response wound healing|up-regulation of connective tissue replacement during inflammatory response|upregulation of fibrosis during inflammatory response Any process that activates or increases the frequency, rate or extent of connective tissue replacement involved in inflammatory response wound healing. CHEBI:49103 drug metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49103 GO:1904597 negative regulation of connective tissue replacement involved in inflammatory response wound healing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904597 down regulation of fibrosis during inflammatory response|negative regulation of connective tissue replacement during inflammatory response|down-regulation of connective tissue replacement during inflammatory response|downregulation of fibrosis during inflammatory response|inhibition of connective tissue replacement involved in inflammatory response wound healing|downregulation of connective tissue replacement during inflammatory response|negative regulation of fibrosis during inflammatory response|down-regulation of fibrosis during inflammatory response|down regulation of connective tissue replacement during inflammatory response|down regulation of connective tissue replacement involved in inflammatory response wound healing|downregulation of connective tissue replacement involved in inflammatory response wound healing|inhibition of connective tissue replacement during inflammatory response|inhibition of fibrosis during inflammatory response|down-regulation of connective tissue replacement involved in inflammatory response wound healing Any process that stops, prevents or reduces the frequency, rate or extent of connective tissue replacement involved in inflammatory response wound healing. CHEBI:49102 malonamate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49102 CHEBI:8359 pratensein biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_8359 CHEBI:25147 mandelate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_25147 CHEBI:25140 maltodextrin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25140 CHEBI:25143 maltose phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25143 CHEBI:15799 1-palmitoyl-sn-glycerol 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15799 CHEBI:15793 3-hydroxyanthranilic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15793 CHEBI:15792 malonate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15792 CHEBI:15795 protoaphin aglucone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15795 CHEBI:15794 juglone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15794 CHEBI:39785 1-pyrroline-2-carboxylic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_39785 CHEBI:15791 (S)-2-halocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15791 CHEBI:25115 malate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25115 CHEBI:40751 (S)-adrenaline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_40751 CHEBI:25111 magnesium porphyrin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25111 CHEBI:40753 9-anthrol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_40753 CL:0002664 cardioblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002664 CPC|cardiovascular progenitor cell A stem cell that can give rise to multiple cell types (i.e. smooth muscle, endothelial) in the developing heart. CHEBI:50091 S-nitrosoglutathione biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50091 CHEBI:74068 erucoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74068 CHEBI:132480 N-icosanoyltaurine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132480 CHEBI:74069 (11Z)-eicosenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74069 CHEBI:49097 (R)-3-aminoisobutyrate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49097 CHEBI:49096 3-aminoisobutyrate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49096 CL:0002679 natural helper lymphocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002679 A lymphocyte found in adipose tissue that lacks lineage markers of other lymphocytes but is capable of mediating TH2 cytokine responses. This cell type is found in fat associated lymphoid clusters, proliferates in response to IL2 and produce large amounts of TH2 cytokines such as IL5, IL6 and IL13 CHEBI:49098 (6R)-2-acetyl-6-(3-acetyl-2,4,6-trihydroxy-5-methylphenyl)-3-hydroxy-6-methylcyclohexa-2,4-dien-1-one biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49098 CL:0002672 retinal progenitor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002672 A multi-fate stem cell that can give rise to different retinal cell types including rod and cone cells. CL:0002671 endothelial stalk cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002671 An endothelial stalk cell is a specialized endothelial cell that follows behind the tip cell of an angiogenic sprout. CL:0002673 tongue muscle cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002673 A skeletal muscle cell that is part of the tongue. CHEBI:74071 (15Z)-3-oxotetracosenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74071 CL:0002676 neural crest derived neuroblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002676 A neuroblast derived from a neural crest cell. CHEBI:74070 (13Z)-3-oxodocosenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74070 CHEBI:132499 fatty acid 16:3 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132499 CL:0002678 memory regulatory T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002678 A CD4-positive, CD25-positive alpha-beta regulatory T cell that has encountered antigen. CHEBI:132494 fatty acid 16:2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132494 CHEBI:8382 prednisone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_8382 CHEBI:49086 CDP-choline(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49086 CHEBI:49085 N-acyl-D-glutamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49085 CHEBI:49088 D-tagatofuranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49088 CHEBI:49087 2,6-dihydroxynicotinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49087 CHEBI:50071 ascopyrone P biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50071 CHEBI:50070 ascopyrone M biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50070 CHEBI:74081 1-archaetidyl-1D-myo-inositol 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74081 CHEBI:74084 (6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74084 CHEBI:49095 beta-amino-acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49095 CHEBI:74083 (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74083 CHEBI:49094 tagatose 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49094 CHEBI:74086 (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74086 CHEBI:50075 dihydropyridine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50075 CHEBI:50073 p-menthadiene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50073 CHEBI:74087 (9Z,12Z,15Z,18Z)-tetracosatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74087 CHEBI:50072 abietadiene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50072 UBERON:4000115 mineralized bone tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_4000115 Bone tissue mineralized with hydroxyapatite. CHEBI:50069 stemar-13-ene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50069 GO:1904509 negative regulation of protein localization to basolateral plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904509 down regulation of protein localization in basolateral plasma membrane|downregulation of protein localization in basolateral plasma membrane|inhibition of protein localisation to basolateral plasma membrane|down regulation of protein localisation in basolateral plasma membrane|down regulation of protein localization to basolateral plasma membrane|downregulation of protein localisation in basolateral plasma membrane|down-regulation of protein localization in basolateral plasma membrane|negative regulation of protein localization in basolateral plasma membrane|downregulation of protein localization to basolateral plasma membrane|down regulation of protein localisation to basolateral plasma membrane|down-regulation of protein localisation in basolateral plasma membrane|inhibition of protein localization in basolateral plasma membrane|negative regulation of protein localisation in basolateral plasma membrane|downregulation of protein localisation to basolateral plasma membrane|down-regulation of protein localization to basolateral plasma membrane|inhibition of protein localisation in basolateral plasma membrane|down-regulation of protein localisation to basolateral plasma membrane|negative regulation of protein localisation to basolateral plasma membrane|inhibition of protein localization to basolateral plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to basolateral plasma membrane. GO:1904508 regulation of protein localization to basolateral plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904508 regulation of protein localization in basolateral plasma membrane|regulation of protein localisation in basolateral plasma membrane|regulation of protein localisation to basolateral plasma membrane Any process that modulates the frequency, rate or extent of protein localization to basolateral plasma membrane. GO:1904507 positive regulation of telomere maintenance in response to DNA damage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904507 up-regulation of DNA damage response, telomere maintenance|up regulation of telomere maintenance in response to DNA damage|upregulation of DNA damage response, telomere maintenance|upregulation of telomere maintenance in response to DNA damage|up regulation of DNA damage response, telomere maintenance|activation of DNA damage response, telomere maintenance|positive regulation of DNA damage response, telomere maintenance|up-regulation of telomere maintenance in response to DNA damage|activation of telomere maintenance in response to DNA damage Any process that activates or increases the frequency, rate or extent of telomere maintenance in response to DNA damage. GO:1904506 negative regulation of telomere maintenance in response to DNA damage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904506 inhibition of DNA damage response, telomere maintenance|down-regulation of telomere maintenance in response to DNA damage|downregulation of telomere maintenance in response to DNA damage|down regulation of DNA damage response, telomere maintenance|down regulation of telomere maintenance in response to DNA damage|downregulation of DNA damage response, telomere maintenance|inhibition of telomere maintenance in response to DNA damage|down-regulation of DNA damage response, telomere maintenance|negative regulation of DNA damage response, telomere maintenance Any process that stops, prevents or reduces the frequency, rate or extent of telomere maintenance in response to DNA damage. CHEBI:49075 2-formylglutaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49075 GO:1904505 regulation of telomere maintenance in response to DNA damage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904505 regulation of DNA damage response, telomere maintenance Any process that modulates the frequency, rate or extent of telomere maintenance in response to DNA damage. CL:0002658 glandular cell of the large intestine biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002658 A glandular epithelial cell of the large intestine. GO:1904504 positive regulation of lipophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904504 up regulation of lipophagy|activation of lipophagy|up-regulation of lipophagy|upregulation of lipophagy Any process that activates or increases the frequency, rate or extent of lipophagy. CL:0002657 glandular cell of esophagus biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002657 A glandular epithelial cell of the esophagus. CHEBI:49077 2-hydroxymethylglutaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49077 GO:1904503 negative regulation of lipophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904503 down-regulation of lipophagy|inhibition of lipophagy|down regulation of lipophagy|downregulation of lipophagy Any process that stops, prevents or reduces the frequency, rate or extent of lipophagy. CL:0002659 glandular cell of stomach biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002659 A glandular epithelial cell that is part of the stomach. GO:1904502 regulation of lipophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904502 Any process that modulates the frequency, rate or extent of lipophagy. GO:1904501 obsolete positive regulation of chromatin-mediated maintenance of transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904501 up regulation of chromatin-mediated maintenance of transcription|activation of chromatin-mediated maintenance of transcription|up-regulation of chromatin-mediated maintenance of transcription|upregulation of chromatin-mediated maintenance of transcription OBSOLETE. Any process that activates or increases the frequency, rate or extent of chromatin-mediated maintenance of transcription. GO:1904500 obsolete negative regulation of chromatin-mediated maintenance of transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904500 down-regulation of chromatin-mediated maintenance of transcription|inhibition of chromatin-mediated maintenance of transcription|down regulation of chromatin-mediated maintenance of transcription|downregulation of chromatin-mediated maintenance of transcription OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of chromatin-mediated maintenance of transcription. CHEBI:132474 fatty acid-taurine conjugate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132474 CHEBI:132473 13-hydroxytetradecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132473 CHEBI:49080 marmesin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49080 CHEBI:132476 N-tetradecanoyltaurine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132476 CHEBI:132475 N-dodecanoyltaurine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132475 CHEBI:50060 ent-cassa-12,15-diene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50060 CHEBI:132477 N-hexadecanoyltaurine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132477 CHEBI:49081 6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49081 CHEBI:49084 N-acyl-D-glutamates(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49084 CHEBI:74095 polyprenyl phospho polysaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74095 CHEBI:132479 N-stearoyltaurine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132479 CHEBI:74094 3-O-phospho-[2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->]n-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74094 CHEBI:74097 3-O-methylphospho-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)]n-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-ditrans,octacis-undecaprenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74097 CHEBI:50064 ent-pimara-9(11),15-diene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50064 CHEBI:50063 ent-pimara-8(14),15-diene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50063 CHEBI:8386 pregnane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_8386 CHEBI:50062 pimaradiene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50062 CHEBI:50061 ent-sandaracopimara-8(14),15-diene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50061 CHEBI:74098 alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)]n-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-ditrans,octacis-undecaprenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74098 CHEBI:50068 stemod-13(17)-ene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50068 CHEBI:50067 9beta-pimara-7,15-diene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50067 CHEBI:50065 D-cystine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50065 GO:0003997 acyl-CoA oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003997 Reactome:R-HSA-2066787|RHEA:38959|Reactome:R-HSA-390256|Reactome:R-HSA-193369|MetaCyc:ACYL-COA-OXIDASE-RXN|EC:1.3.3.6|Reactome:R-HSA-192335 acyl coenzyme A oxidase activity|fatty acyl-CoA oxidase activity|acyl-CoA:oxygen 2-oxidoreductase activity|fatty acyl-coenzyme A oxidase activity Catalysis of the reaction: acyl-CoA + O2 = trans-2,3-dehydroacyl-CoA + hydrogen peroxide. GO:0003996 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003996 GO:0003999 adenine phosphoribosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003999 MetaCyc:ADENPRIBOSYLTRAN-RXN|RHEA:16609|Reactome:R-HSA-74213|EC:2.4.2.7 adenylic pyrophosphorylase activity|transphosphoribosidase activity|AMP:diphosphate phospho-D-ribosyltransferase activity|AMP pyrophosphorylase activity|AMP diphosphorylase activity|adenine phosphoribosylpyrophosphate transferase activity|AMP-pyrophosphate phosphoribosyltransferase activity|adenosine phosphoribosyltransferase activity|APRT activity|adenylate pyrophosphorylase activity Catalysis of the reaction: AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate. CHEBI:50059 imidazolium cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50059 GO:0003998 acylphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003998 RHEA:14965|EC:3.6.1.7|MetaCyc:ACYLPHOSPHATASE-RXN 1,3-diphosphoglycerate phosphatase activity|acetylphosphatase activity|GP 1-3|Ho 1-3|acylphosphate phosphohydrolase activity|acetic phosphatase activity Catalysis of the reaction: an acyl phosphate + H2O = a carboxylate + phosphate. CHEBI:50058 L-cystine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50058 GO:0003993 acid phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003993 Reactome:R-HSA-196950|MetaCyc:ACID-PHOSPHATASE-RXN|EC:3.1.3.2 acid monophosphatase activity|uteroferrin|orthophosphoric-monoester phosphohydrolase (acid optimum)|acid phosphomonoester hydrolase activity|phosphate-monoester phosphohydrolase (acid optimum)|acid nucleoside diphosphate phosphatase activity|acid phosphomonoesterase activity|glycerophosphatase activity|acid phosphohydrolase activity|phosphomonoesterase activity Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an acid pH optimum. GO:1904519 protein localization to microtubule minus-end biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904519 protein localisation in microtubule minus-end|protein localisation to microtubule minus-end|protein localization in microtubule minus-end A process in which a protein is transported to, or maintained in, a location at a microtubule minus-end. GO:0003992 N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003992 EC:2.6.1.11|RHEA:18049|KEGG_REACTION:R02283|MetaCyc:ACETYLORNTRANSAM-RXN succinylornithine aminotransferase activity|N-acetylornithine aminotransferase activity|ACOAT activity|N2-acetylornithine 5-aminotransferase activity|N(2)-acetylornithine 5-transaminase activity|acetylornithine delta-transaminase activity|acetylornithine aminotransferase activity|N2-acetyl-L-ornithine:2-oxoglutarate aminotransferase activity|N2-acetylornithine 5-transaminase activity|N-acetylornithine-delta-transaminase activity|2-N-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity|acetylornithine transaminase activity|acetylornithine 5-aminotransferase activity Catalysis of the reaction: 2-oxoglutarate + N(2)-acetyl-L-ornithine = N-acetyl-L-glutamate 5-semialdehyde + L-glutamate. GO:1904518 protein localization to cytoplasmic microtubule plus-end biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904518 protein localisation to cytoplasmic microtubule plus-end|protein localisation in cytoplasmic microtubule plus-end|protein localization in cytoplasmic microtubule plus-end A process in which a protein is transported to, or maintained in, a location at a cytoplasmic microtubule plus-end. GO:0003995 acyl-CoA dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003995 Reactome:R-HSA-77274|Reactome:R-HSA-77319|Reactome:R-HSA-77338|Reactome:R-HSA-77327|Reactome:R-HSA-109341|Reactome:R-HSA-77345|MetaCyc:LONG-CHAIN-FATTY-ACYL-COA-REDUCTASE-RXN|MetaCyc:ACYLCOADEHYDROG-RXN|Reactome:R-HSA-5695980|Reactome:R-HSA-70859|Reactome:R-HSA-77263|Reactome:R-HSA-70800|EC:1.3.99.3|Reactome:R-HSA-77299|Reactome:R-HSA-5695989 acyl-CoA reductase activity|acyl-CoA:(acceptor) 2,3-oxidoreductase activity|general acyl CoA dehydrogenase activity|long-chain acyl coenzyme A dehydrogenase activity|medium-chain acyl-CoA dehydrogenase activity|acyl CoA dehydrogenase activity|fatty-acyl-CoA dehydrogenase activity|acyl-CoA:acceptor 2,3-oxidoreductase activity|long-chain acyl-CoA dehydrogenase activity|medium-chain acyl-coenzyme A dehydrogenase activity|acyl dehydrogenase activity|fatty acyl coenzyme A dehydrogenase activity|acyl coenzyme A dehydrogenase activity Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor. GO:0003994 aconitate hydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003994 RHEA:10336|EC:4.2.1.3|Reactome:R-HSA-450975|Reactome:R-HSA-70971|Reactome:R-HSA-5690911 citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|cis-aconitase activity|citrate(isocitrate) hydro-lyase activity|aconitase activity|citrate hydro-lyase activity Catalysis of the reaction: citrate = isocitrate. The reaction occurs in two steps: (1) citrate = cis-aconitate + H2O, (2) cis-aconitate + H2O = isocitrate. This reaction is the interconversion of citrate and isocitrate via the labile, enzyme-bound intermediate cis-aconitate. Water is removed from one part of the citrate molecule and added back to a different atom to form isocitrate. GO:1904517 MgATP(2-) binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1904517 Interacting selectively and non-covalently with MgATP(2-). CHEBI:25097 lyxose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25097 CHEBI:132449 wax ester 36:1 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132449 GO:1904516 myofibroblast cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904516 MFB apoptosis|MFB apoptotic process|myofibroblast cell apoptosis Any apoptotic process in a myofibroblast cell. CL:0002625 seminiferous tubule epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002625 A cell of the seminiferous tubule epithelium. CHEBI:49064 4-phosphothreonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49064 GO:1904515 positive regulation of TORC2 signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904515 up-regulation of TORC2 signal transduction|upregulation of TORC2 signaling|upregulation of TORC2 signal transduction|up regulation of TORC2 signaling|activation of TORC2 signaling|up regulation of TORC2 signal transduction|activation of TORC2 signal transduction|positive regulation of TORC2 signal transduction|up-regulation of TORC2 signaling Any process that activates or increases the frequency, rate or extent of TORC2 signaling. GO:1904514 positive regulation of initiation of premeiotic DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904514 positive regulation of initiation of meiotic DNA synthesis|activation of initiation of premeiotic DNA synthesis|up regulation of premeiotic DNA replication initiation|activation of premeiotic DNA replication initiation|positive regulation of initiation of premeiotic DNA synthesis|upregulation of meiotic DNA replication initiation|activation of initiation of meiotic DNA synthesis|positive regulation of premeiotic DNA replication initiation|up regulation of initiation of premeiotic DNA synthesis|up regulation of initiation of premeiotic DNA replication|up-regulation of initiation of meiotic DNA synthesis|up-regulation of meiotic DNA replication initiation|up-regulation of premeiotic DNA replication initiation|upregulation of initiation of premeiotic DNA synthesis|upregulation of initiation of meiotic DNA synthesis|upregulation of initiation of premeiotic DNA replication|activation of meiotic DNA replication initiation|positive regulation of meiotic DNA replication initiation|upregulation of premeiotic DNA replication initiation|up-regulation of initiation of premeiotic DNA synthesis|up regulation of meiotic DNA replication initiation|up-regulation of initiation of premeiotic DNA replication|up regulation of initiation of meiotic DNA synthesis|activation of initiation of premeiotic DNA replication Any process that activates or increases the frequency, rate or extent of initiation of premeiotic DNA replication. GO:0003991 acetylglutamate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003991 RHEA:14629|MetaCyc:ACETYLGLUTKIN-RXN|EC:2.7.2.8 acetylglutamate phosphokinase activity|N-acetylglutamate phosphokinase activity|N-acetylglutamate kinase activity|N-acetylglutamate 5-phosphotransferase activity|ATP:N-acetyl-L-glutamate 5-phosphotransferase activity|N-acetylglutamic 5-phosphotransferase activity Catalysis of the reaction: ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate-5-phosphate. NCBITaxon:2611341 Metamonada organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_2611341 CHEBI:25095 L-lysine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25095 GO:1904513 negative regulation of initiation of premeiotic DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904513 downregulation of premeiotic DNA replication initiation|negative regulation of initiation of premeiotic DNA synthesis|down-regulation of initiation of premeiotic DNA synthesis|down regulation of meiotic DNA replication initiation|down-regulation of initiation of premeiotic DNA replication|negative regulation of initiation of meiotic DNA synthesis|down-regulation of initiation of meiotic DNA synthesis|inhibition of meiotic DNA replication initiation|down-regulation of premeiotic DNA replication initiation|negative regulation of premeiotic DNA replication initiation|downregulation of initiation of premeiotic DNA synthesis|downregulation of initiation of premeiotic DNA replication|down regulation of initiation of premeiotic DNA synthesis|inhibition of premeiotic DNA replication initiation|inhibition of initiation of meiotic DNA synthesis|down regulation of initiation of premeiotic DNA replication|inhibition of initiation of premeiotic DNA replication|down-regulation of meiotic DNA replication initiation|inhibition of initiation of premeiotic DNA synthesis|negative regulation of meiotic DNA replication initiation|down regulation of initiation of meiotic DNA synthesis|downregulation of initiation of meiotic DNA synthesis|down regulation of premeiotic DNA replication initiation|downregulation of meiotic DNA replication initiation Any process that stops, prevents or reduces the frequency, rate or extent of initiation of premeiotic DNA replication. GO:0003990 acetylcholinesterase activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0003990 EC:3.1.1.7|RHEA:17561|MetaCyc:ACETYLCHOLINESTERASE-RXN|Reactome:R-HSA-372519 acetylthiocholinesterase activity|choline esterase I activity|acetylcholine acetylhydrolase activity|AcCholE|acetylcholine hydrolase activity|true cholinesterase activity|acetyl.beta-methylcholinesterase activity Catalysis of the reaction: acetylcholine + H2O = choline + acetate. CHEBI:25094 lysine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25094 CHEBI:49065 phosphothreonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49065 GO:1904512 regulation of initiation of premeiotic DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904512 regulation of initiation of premeiotic DNA synthesis|regulation of initiation of meiotic DNA synthesis|regulation of premeiotic DNA replication initiation|regulation of meiotic DNA replication initiation Any process that modulates the frequency, rate or extent of initiation of premeiotic DNA replication. CL:0002629 mature microglial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002629 mature microglia|reactive microglia|activated microglia A mature microglial cell that has changed shape to an amoeboid morphology and is capable of cytokine production and antigen presentation. GO:1904511 cytoplasmic microtubule plus-end biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1904511 microtubule plus end of non-spindle-associated astral microtubule|microtubule plus end of cytoplasmic microtubule|growing microtubule plus end of non-spindle-associated astral microtubule|growing microtubule plus end of cytoplasmic microtubule|microtubule plus-end of cytoplasmic microtubule|microtubule plus-end of non-spindle-associated astral microtubule Any microtubule plus-end that is part of a cytoplasmic microtubule. GO:1904510 positive regulation of protein localization to basolateral plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904510 up regulation of protein localisation to basolateral plasma membrane|positive regulation of protein localisation to basolateral plasma membrane|activation of protein localisation to basolateral plasma membrane|up-regulation of protein localisation in basolateral plasma membrane|upregulation of protein localization in basolateral plasma membrane|up-regulation of protein localization to basolateral plasma membrane|upregulation of protein localisation in basolateral plasma membrane|up-regulation of protein localisation to basolateral plasma membrane|upregulation of protein localization to basolateral plasma membrane|up regulation of protein localization in basolateral plasma membrane|positive regulation of protein localization in basolateral plasma membrane|activation of protein localization in basolateral plasma membrane|upregulation of protein localisation to basolateral plasma membrane|up regulation of protein localisation in basolateral plasma membrane|positive regulation of protein localisation in basolateral plasma membrane|activation of protein localisation in basolateral plasma membrane|up regulation of protein localization to basolateral plasma membrane|activation of protein localization to basolateral plasma membrane|up-regulation of protein localization in basolateral plasma membrane Any process that activates or increases the frequency, rate or extent of protein localization to basolateral plasma membrane. CHEBI:49069 4-phospho-D-threonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49069 CHEBI:49071 3-[(5S,6R)-5,6-dihydroxycyclohexa-1,3-dienyl]acrylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49071 CL:0002620 skin fibroblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002620 A fibroblast of skin. CHEBI:49070 3-[(5R,6S)-5,6-dihydroxycyclohexa-1,3-dienyl]acrylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49070 CL:0002623 acinar cell of salivary gland biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002623 An acinar cell of salivary gland. CHEBI:49072 (R)-2,3-dihydroxy-3-methylbutanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49072 CL:0002622 prostate stromal cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002622 A stromal cell of the prostate. CHEBI:50051 cystine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50051 CL:1000090 pronephric nephron tubule epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000090 CHEBI:50048 phenylethylamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50048 CHEBI:50047 organic amino compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50047 GO:1904529 regulation of actin filament binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904529 regulation of F-actin binding|regulation of actin cross-linking activity Any process that modulates the frequency, rate or extent of actin filament binding. GO:1904528 positive regulation of microtubule binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904528 up-regulation of microtubule severing activity|upregulation of microtubule/chromatin interaction|up regulation of microtubule binding|upregulation of microtubule severing activity|activation of microtubule binding|up regulation of microtubule/chromatin interaction|positive regulation of microtubule/chromatin interaction|activation of microtubule/chromatin interaction|up regulation of microtubule severing activity|up-regulation of microtubule binding|positive regulation of microtubule severing activity|up-regulation of microtubule/chromatin interaction|activation of microtubule severing activity|upregulation of microtubule binding Any process that activates or increases the frequency, rate or extent of microtubule binding. GO:1904527 negative regulation of microtubule binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904527 down regulation of microtubule binding|down regulation of microtubule/chromatin interaction|downregulation of microtubule binding|inhibition of microtubule severing activity|downregulation of microtubule/chromatin interaction|down regulation of microtubule severing activity|down-regulation of microtubule binding|downregulation of microtubule severing activity|down-regulation of microtubule/chromatin interaction|negative regulation of microtubule/chromatin interaction|inhibition of microtubule binding|negative regulation of microtubule severing activity|down-regulation of microtubule severing activity|inhibition of microtubule/chromatin interaction Any process that stops, prevents or reduces the frequency, rate or extent of microtubule binding. GO:1904526 regulation of microtubule binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904526 regulation of microtubule/chromatin interaction|regulation of microtubule severing activity Any process that modulates the frequency, rate or extent of microtubule binding. CHEBI:49052 ureidocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49052 GO:1904525 positive regulation of DNA amplification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904525 upregulation of DNA amplification|up regulation of DNA amplification|activation of DNA amplification|up-regulation of DNA amplification Any process that activates or increases the frequency, rate or extent of DNA amplification. CHEBI:49055 4-phosphoerythronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49055 NCBITaxon:2611352 Discoba organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_2611352 GO:1904524 negative regulation of DNA amplification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904524 down regulation of DNA amplification|downregulation of DNA amplification|down-regulation of DNA amplification|inhibition of DNA amplification Any process that stops, prevents or reduces the frequency, rate or extent of DNA amplification. GO:1904523 regulation of DNA amplification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904523 Any process that modulates the frequency, rate or extent of DNA amplification. CHEBI:49057 (all-E)-deca-2,4,6,8-tetraenedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49057 CL:0002639 amniotic stem cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002639 An amniotic stem cell is a mesenchymalstem cell extracted from amniotic fluid. Amniotic stem cells are able to differentiate into various tissue type such as skin, cartilage, cardiac tissue, nerves, muscle, and bone GO:1904522 positive regulation of myofibroblast cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904522 up regulation of MFB apoptotic process|upregulation of myofibroblast cell apoptotic process|activation of MFB apoptosis|activation of MFB apoptotic process|positive regulation of MFB apoptotic process|up-regulation of myofibroblast cell apoptosis|up-regulation of MFB apoptosis|up-regulation of myofibroblast cell apoptotic process|activation of myofibroblast cell apoptosis|activation of myofibroblast cell apoptotic process|up-regulation of MFB apoptotic process|positive regulation of myofibroblast cell apoptosis|up regulation of myofibroblast cell apoptosis|upregulation of MFB apoptosis|upregulation of MFB apoptotic process|up regulation of myofibroblast cell apoptotic process|upregulation of myofibroblast cell apoptosis|up regulation of MFB apoptosis|positive regulation of MFB apoptosis Any process that activates or increases the frequency, rate or extent of myofibroblast cell apoptotic process. CHEBI:49056 4-phospho-L-erythronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49056 GO:1904521 negative regulation of myofibroblast cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904521 inhibition of myofibroblast cell apoptotic process|inhibition of myofibroblast cell apoptosis|down-regulation of MFB apoptosis|negative regulation of MFB apoptosis|negative regulation of MFB apoptotic process|down-regulation of MFB apoptotic process|negative regulation of myofibroblast cell apoptosis|down-regulation of myofibroblast cell apoptosis|inhibition of MFB apoptosis|inhibition of MFB apoptotic process|down-regulation of myofibroblast cell apoptotic process|down regulation of MFB apoptosis|downregulation of myofibroblast cell apoptosis|down regulation of myofibroblast cell apoptosis|downregulation of MFB apoptosis|down regulation of MFB apoptotic process|downregulation of myofibroblast cell apoptotic process|down regulation of myofibroblast cell apoptotic process|downregulation of MFB apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of myofibroblast cell apoptotic process. CHEBI:49059 D-threonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49059 GO:1904520 regulation of myofibroblast cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904520 regulation of MFB apoptosis|regulation of myofibroblast cell apoptosis|regulation of MFB apoptotic process Any process that modulates the frequency, rate or extent of myofibroblast cell apoptotic process. CHEBI:49058 L-erythronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49058 GO:1904530 negative regulation of actin filament binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904530 inhibition of F-actin binding|downregulation of actin cross-linking activity|down regulation of actin cross-linking activity|down regulation of F-actin binding|down-regulation of actin filament binding|inhibition of actin cross-linking activity|downregulation of F-actin binding|downregulation of actin filament binding|negative regulation of F-actin binding|down-regulation of F-actin binding|negative regulation of actin cross-linking activity|down-regulation of actin cross-linking activity|down regulation of actin filament binding|inhibition of actin filament binding Any process that stops, prevents or reduces the frequency, rate or extent of actin filament binding. CL:0002630 actinomycete-type spore biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002630 A spore formed from bacteria in the order Actinomycetales. CL:0002632 epithelial cell of lower respiratory tract biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002632 CHEBI:49060 2,3,4-trihydroxybutanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49060 CHEBI:49062 tetronic acid phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49062 CL:0002633 respiratory basal cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002633 airway basal cell|airway basal stem cell A basal cell in the respiratory tract. CHEBI:49061 2,3,4-trihydroxybutanoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49061 CHEBI:50042 alpha-thujone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50042 CHEBI:50041 thujane monoterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50041 CHEBI:156403 hydroperoxy fatty amide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_156403 CHEBI:50040 thujone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50040 CHEBI:50043 (+)-alpha-thujone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50043 GO:0003975 UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003975 Reactome:R-HSA-4549334|Reactome:R-HSA-446191|RHEA:13289|EC:2.7.8.15|MetaCyc:2.7.8.15-RXN UDP-N-acetyl-D-glucosamine:dolichol phosphate N-acetyl-D-glucosamine-1-phosphate transferase activity|chitobiosylpyrophosphoryldolichol synthase activity|GlcNAc-1-P transferase activity|UDP-GlcNAc:dolichyl-phosphate GlcNAc-1-phosphate transferase activity|UDP-N-acetyl-D-glucosamine:dolichyl-phosphate N-acetyl-D-glucosaminephosphotransferase activity|UDP-D-N-acetylglucosamine N-acetylglucosamine 1-phosphate transferase activity|UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosamine-1-phosphate transferase activity|UDP-acetylglucosamine-dolichol phosphate acetylglucosamine phosphotransferase activity|uridine diphosphoacetylglucosamine-dolichyl phosphate acetylglucosamine-1-phosphotransferase activity|dolichol phosphate N-acetylglucosamine-1-phosphotransferase activity|UDP-acetylglucosamine-dolichol phosphate acetylglucosamine-1-phosphotransferase activity|N-acetylglucosamine-1-phosphate transferase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UMP + N-acetyl-D-glucosaminyl-diphosphodolichol. GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003974 RHEA:20517|EC:5.1.3.7|MetaCyc:UDP-N-ACETYLGLUCOSAMINE-4-EPIMERASE-RXN UDP-GlcNAc 4-epimerase activity|uridine diphosphate N-acetylglucosamine-4-epimerase activity|UDP acetylglucosamine epimerase activity|uridine 5'-diphospho-N-acetylglucosamine-4-epimerase activity|uridine diphosphoacetylglucosamine epimerase activity|UDP-N-acetyl-D-glucosamine 4-epimerase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-galactosamine. CHEBI:49049 3-oxo-3-ureidopropanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49049 CHEBI:50038 deoxyhypusine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50038 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003977 RHEA:13509|KEGG_REACTION:R00416|MetaCyc:NAG1P-URIDYLTRANS-RXN|Reactome:R-HSA-446204|EC:2.7.7.23 uridine diphosphoacetylglucosamine pyrophosphorylase activity|UDP-GlcNAc pyrophosphorylase activity|UTP:2-acetamido-2-deoxy-alpha-D-glucose-1-phosphate uridylyltransferase activity|UTP:N-acetyl-alpha-D-glucosamine-1-phosphate uridylyltransferase activity|uridine diphosphoacetylglucosamine phosphorylase activity|N-acetylglucosamine-1-phosphate uridyltransferase activity|UDP-acetylglucosamine pyrophosphorylase activity|acetylglucosamine 1-phosphate uridylyltransferase|uridine diphosphate-N-acetylglucosamine pyrophosphorylase activity|GlmU uridylyltransferase activity|UDP-N-acetylglucosamine pyrophosphorylase activity Catalysis of the reaction: N-acetyl-alpha-D-glucosamine 1-phosphate + UTP = diphosphate + UDP-N-acetyl-alpha-D-glucosamine. CHEBI:50037 N-benzoylanthranilic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50037 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003976 EC:2.7.8.17|RHEA:13581|MetaCyc:2.7.8.17-RXN UDP-GlcNAc:glycoprotein N-acetylglucosamine-1-phosphotransferase activity|UDP-N-acetylglucosamine:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase activity|UDP-N-acetyl-D-glucosamine:lysosomal-enzyme N-acetylglucosaminephosphotransferase activity|UDP-N-acetylglucosamine:glycoprotein N-acetylglucosaminyl-1-phosphotransferase activity|N-acetylglucosaminylphosphotransferase activity|UDP-N-acetylglucosamine:glycoprotein N-acetylglucosamine-1-phosphotransferase activity|N-acetylglucosaminyl phosphotransferase activity|lysosomal enzyme precursor acetylglucosamine-1-phosphotransferase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + lysosomal-enzyme D-mannose = UMP + lysosomal-enzyme N-acetyl-D-glucosaminyl-phospho-D-mannose. CHEBI:50036 (6aS,11aS)-4-dimethylallyl-3,6a,9-trihydroxypterocarpan biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50036 GO:0003971 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003971 GO:0003973 (S)-2-hydroxy-acid oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003973 EC:1.1.3.15|RHEA:16789|MetaCyc:S-2-HYDROXY-ACID-OXIDASE-RXN hydroxyacid oxidase A|L-2-hydroxy acid oxidase|(S)-2-hydroxy-acid:oxygen 2-oxidoreductase|hydroxy-acid oxidase A activity|hydroxy-acid oxidase B activity|L-alpha-hydroxy acid oxidase|oxidase, L-2-hydroxy acid Catalysis of the reaction: (S)-2-hydroxy-acid + O2 = 2-oxo acid + hydrogen peroxide. GO:1904539 negative regulation of glycolytic process through fructose-6-phosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904539 negative regulation of glycolysis through fructose-6-phosphate|down-regulation of glycolytic process through fructose-6-phosphate|down-regulation of glycolysis through fructose-6-phosphate|inhibition of glycolytic process through fructose-6-phosphate|inhibition of glycolysis through fructose-6-phosphate|down regulation of glycolysis through fructose-6-phosphate|down regulation of glycolytic process through fructose-6-phosphate|downregulation of glycolytic process through fructose-6-phosphate|downregulation of glycolysis through fructose-6-phosphate Any process that stops, prevents or reduces the frequency, rate or extent of glycolytic process through fructose-6-phosphate. GO:0003972 RNA ligase (ATP) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003972 MetaCyc:RNA-LIGASE-ATP-RXN|EC:6.5.1.3|Reactome:R-HSA-5696816 poly(ribonucleotide):poly(ribonucleotide) ligase (AMP-forming)|ribonucleic ligase activity|polyribonucleotide ligase activity|polyribonucleotide synthase (ATP) activity Catalysis of the reaction: ATP + ribonucleotide(n) + ribonucleotide(m) = AMP + diphosphate + ribonucleotide(n+m). CL:0002603 astrocyte of the cerebellum biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002603 An astrocyte of the cerebellum. GO:1904538 regulation of glycolytic process through fructose-6-phosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904538 regulation of glycolysis through fructose-6-phosphate Any process that modulates the frequency, rate or extent of glycolytic process through fructose-6-phosphate. GO:1904537 negative regulation of mitotic telomere tethering at nuclear periphery biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904537 downregulation of mitotic telomere tethering at nuclear periphery|down-regulation of mitotic telomere tethering at nuclear periphery|inhibition of mitotic telomere tethering at nuclear periphery|down regulation of mitotic telomere tethering at nuclear periphery Any process that stops, prevents or reduces the frequency, rate or extent of mitotic telomere tethering at nuclear periphery. CL:0002605 astrocyte of the cerebral cortex biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002605 An astrocyte of the cerebral cortex. CHEBI:49044 (-)-germacrene D biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49044 GO:1904536 regulation of mitotic telomere tethering at nuclear periphery biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904536 Any process that modulates the frequency, rate or extent of mitotic telomere tethering at nuclear periphery. GO:1904535 positive regulation of telomeric loop disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904535 upregulation of T loop disassembly|up regulation of telomeric loop disassembly|up-regulation of T loop disassembly|activation of T loop disassembly|upregulation of telomeric loop disassembly|positive regulation of T loop disassembly|up-regulation of telomeric loop disassembly|up regulation of T loop disassembly|activation of telomeric loop disassembly Any process that activates or increases the frequency, rate or extent of telomeric loop disassembly. CL:0002604 astrocyte of the hippocampus biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002604 CHEBI:49043 beta-lactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49043 CHEBI:25072 lombricine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25072 GO:1904534 negative regulation of telomeric loop disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904534 inhibition of T loop disassembly|downregulation of telomeric loop disassembly|down regulation of telomeric loop disassembly|inhibition of telomeric loop disassembly|down-regulation of T loop disassembly|negative regulation of T loop disassembly|downregulation of T loop disassembly|down-regulation of telomeric loop disassembly|down regulation of T loop disassembly Any process that stops, prevents or reduces the frequency, rate or extent of telomeric loop disassembly. CHEBI:49046 (+)-germacrene D biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49046 CL:0002607 migratory enteric neural crest cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002607 A neural crest cell that gives rise to cells of the enteric nervous system. CL:0002606 astrocyte of the spinal cord biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002606 An astrocyte of the spinal cord. GO:1904533 regulation of telomeric loop disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904533 regulation of T loop disassembly Any process that modulates the frequency, rate or extent of telomeric loop disassembly. CHEBI:49045 germacrene D biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49045 CHEBI:25078 luciferin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25078 CL:0002609 neuron of cerebral cortex biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002609 cortical neuron A CNS neuron of the cerebral cortex. GO:1904532 obsolete ATP-dependent microtubule motor activity, minus-end-directed involved in microtubule-based movement biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1904532 OBSOLETE. Any ATP-dependent microtubule motor activity, minus-end-directed that is involved in microtubule-based movement. GO:1904531 positive regulation of actin filament binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904531 positive regulation of actin cross-linking activity|upregulation of actin filament binding|up-regulation of F-actin binding|up regulation of actin cross-linking activity|up-regulation of actin filament binding|activation of actin filament binding|upregulation of F-actin binding|upregulation of actin cross-linking activity|up regulation of F-actin binding|up-regulation of actin cross-linking activity|up regulation of actin filament binding|activation of F-actin binding|positive regulation of F-actin binding|activation of actin cross-linking activity Any process that activates or increases the frequency, rate or extent of actin filament binding. CL:0002608 hippocampal neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002608 A neuron of the hippocampus. GO:1904541 fungal-type cell wall disassembly involved in conjugation with cellular fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904541 fungal-type cell wall disassembly involved in mating|fungal-type cell wall disassembly involved in cell fusion Any fungal-type cell wall disassembly that is involved in conjugation with cellular fusion. GO:1904540 positive regulation of glycolytic process through fructose-6-phosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904540 upregulation of glycolytic process through fructose-6-phosphate|upregulation of glycolysis through fructose-6-phosphate|up regulation of glycolytic process through fructose-6-phosphate|up regulation of glycolysis through fructose-6-phosphate|activation of glycolysis through fructose-6-phosphate|activation of glycolytic process through fructose-6-phosphate|positive regulation of glycolysis through fructose-6-phosphate|up-regulation of glycolysis through fructose-6-phosphate|up-regulation of glycolytic process through fructose-6-phosphate Any process that activates or increases the frequency, rate or extent of glycolytic process through fructose-6-phosphate. CHEBI:49051 5,7-dihydro-1H-purine-2,6,8(9H)-trione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49051 CL:0002601 uterine smooth muscle cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002601 A smooth muscle cell of the uterus. CHEBI:49050 ureidoglycolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49050 PR:000012059 oncostatin-M biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000012059 OSM A protein that is a translation product of the human OSM gene or a 1:1 ortholog thereof. CHEBI:50030 thujene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50030 GO:0003979 UDP-glucose 6-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003979 EC:1.1.1.22|KEGG_REACTION:R00286|Reactome:R-HSA-173597|RHEA:23596|MetaCyc:UGD-RXN Catalysis of the reaction: H(2)O + 2 NAD(+) + UDP-alpha-D-glucose = 3 H(+) + 2 NADH + UDP-alpha-D-glucuronate. GO:0003978 UDP-glucose 4-epimerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003978 Reactome:R-HSA-5610036|MetaCyc:UDPGLUCEPIM-RXN|RHEA:22168|EC:5.1.3.2|Reactome:R-HSA-70369 4-epimerase activity|UDPgalactose 4-epimerase activity|uridine diphosphate galactose 4-epimerase activity|uridine diphospho-galactose-4-epimerase activity|uridine diphosphoglucose epimerase activity|UDP-D-galactose 4-epimerase activity|UDPglucose 4-epimerase activity|uridine diphosphate glucose 4-epimerase activity|uridine diphosphoglucose 4-epimerase activity|UDP-galactose 4-epimerase activity|UDPG-4-epimerase activity|galactowaldenase activity|UDP-glucose epimerase activity Catalysis of the reaction: UDP-glucose = UDP-galactose. CHEBI:50034 phellandrene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50034 CHEBI:49039 3-dehydro-L-gulonic acid 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49039 GO:0003986 acetyl-CoA hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003986 MetaCyc:ACETYL-COA-HYDROLASE-RXN|Reactome:R-HSA-390304|EC:3.1.2.1|Reactome:R-HSA-2066779|KEGG_REACTION:R00227|RHEA:20289 acetyl coenzyme A hydrolase activity|acetyl-CoA thiol esterase activity|acetyl coenzyme A deacylase activity|acetyl coenzyme A acylase activity|acetyl-CoA deacylase activity|acetyl-CoA acylase activity Catalysis of the reaction: acetyl-CoA + H(2)O = acetate + CoA + H(+). CHEBI:50028 (-)-sabinene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50028 GO:0003985 acetyl-CoA C-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003985 Reactome:R-HSA-8848215|Reactome:R-HSA-74181|Reactome:R-HSA-70844|MetaCyc:ACETYL-COA-ACETYLTRANSFER-RXN|UM-BBD_enzymeID:e0144|RHEA:21036|Reactome:R-HSA-73916|EC:2.3.1.9 3-oxothiolase activity|acetyl-CoA acetyltransferase activity|thiolase II|acetyl-CoA:acetyl-CoA C-acetyltransferase activity|acetyl-CoA:N-acetyltransferase activity|acetoacetyl-CoA thiolase activity|acetyl coenzyme A thiolase activity|beta-acetoacetyl coenzyme A thiolase activity|2-methylacetoacetyl-CoA thiolase Catalysis of the reaction: 2 acetyl-CoA = CoA + acetoacetyl-CoA. CHEBI:50027 sabinene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50027 CHEBI:49038 L-methionyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49038 GO:0003988 acetyl-CoA C-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003988 UM-BBD_reactionID:r1051|Reactome:R-HSA-77271|Reactome:R-HSA-77304|Reactome:R-HSA-390250|EC:2.3.1.16|MetaCyc:KETOACYLCOATHIOL-RXN|Reactome:R-HSA-77329|Reactome:R-HSA-77309|Reactome:R-HSA-77340|Reactome:R-HSA-8874745|RHEA:21564|Reactome:R-HSA-77321 long-chain 3-oxoacyl-CoA thiolase activity|3-oxoacyl-coenzyme A thiolase activity|2-methylacetoacetyl-CoA thiolase|thiolase I|beta-ketoacyl-CoA thiolase activity|2-keto-acyl thiolase activity|3-ketoacyl CoA thiolase activity|3-ketothiolase activity|ketoacyl-coenzyme A thiolase activity|beta-ketothiolase activity|6-oxoacyl-CoA thiolase activity|pro-3-ketoacyl-CoA thiolase activity|3-ketoacyl-CoA thiolase activity|KAT|3-ketoacyl coenzyme A thiolase activity|3-oxoacyl-CoA thiolase activity|acyl-CoA:acetyl-CoA C-acyltransferase activity|beta-ketoacyl coenzyme A thiolase activity|acetoacetyl-CoA beta-ketothiolase activity|3-ketoacyl thiolase activity|acetyl-CoA acyltransferase activity|oxoacyl-coenzyme A thiolase activity|beta-ketoadipyl coenzyme A thiolase activity|beta-ketoadipyl-CoA thiolase activity|ketoacyl-CoA acyltransferase activity Catalysis of the reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA. CHEBI:50026 (+)-beta-pinene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50026 GO:0003987 acetate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003987 RHEA:23176|EC:6.2.1.1|Reactome:R-HSA-71735|Reactome:R-HSA-449911|Reactome:R-HSA-8875071|MetaCyc:ACETATE--COA-LIGASE-RXN acetyl CoA ligase activity|acetic thiokinase activity|short-chain acyl-coenzyme A synthetase activity|acetyl activating enzyme|acetyl-CoA synthetase activity|acetyl CoA synthase activity|acyl-activating enzyme activity|ACS|acetyl coenzyme A synthetase activity|acetyl-coenzyme A synthase activity|acetate thiokinase activity|short chain fatty acyl-CoA synthetase activity|acetate:CoA ligase (AMP-forming)|acetyl-activating enzyme activity|acetate to acetyl-CoA|acetyl-CoA synthase activity Catalysis of the reaction: ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA. CHEBI:50025 beta-pinene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50025 GO:0003982 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003982 GO:0003981 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003981 GO:0003984 acetolactate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003984 EC:2.2.1.6|MetaCyc:ACETOLACTSYN-RXN|RHEA:25249 alpha-acetohydroxyacid synthase activity|alpha-acetolactate synthase activity|acetohydroxy acid synthetase activity|acetolactate pyruvate-lyase (carboxylating) activity|acetohydroxyacid synthase activity|acetolactic synthetase activity|alpha-acetolactate synthetase activity|alpha-acetohydroxy acid synthetase activity|pyruvate:pyruvate acetaldehydetransferase (decarboxylating) Catalysis of the reaction: 2 pyruvate = 2-acetolactate + CO2. GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003983 Reactome:R-HSA-70286|MetaCyc:GLUC1PURIDYLTRANS-RXN|EC:2.7.7.9|KEGG_REACTION:R00289|RHEA:19889 UDP-glucose pyrophosphorylase activity|uridine-diphosphate glucose pyrophosphorylase activity|UDP-glucose diphosphorylase activity|UDPG pyrophosphorylase activity|UTP:alpha-D-glucose-1-phosphate uridylyltransferase activity|glucose-1-phosphate uridylyltransferase activity|UDPG phosphorylase activity|UTP-glucose-1-phosphate uridylyltransferase activity|UDP glucose pyrophosphorylase activity|uridine diphosphoglucose pyrophosphorylase activity|uridine diphosphate-D-glucose pyrophosphorylase activity|uridine 5'-diphosphoglucose pyrophosphorylase activity Catalysis of the reaction: alpha-D-glucose 1-phosphate + UTP = diphosphate + UDP-D-glucose. CHEBI:50029 (+)-sabinene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50029 CHEBI:49031 L-methionine (S)-S-oxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49031 CL:0002614 neuron of the substantia nigra biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002614 A neuron of the substantia nigra. CL:0002613 striatum neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002613 A neuron of the striatum. CHEBI:49030 (R)-2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49030 GO:1904547 regulation of cellular response to glucose starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904547 Any process that modulates the frequency, rate or extent of cellular response to glucose starvation. GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003980 Reactome:R-HSA-548884 UGGT activity Catalysis of the addition of UDP-glucose on to asparagine-linked (N-linked) oligosaccharides of the form Man7-9GlcNAc2 on incorrectly folded glycoproteins. CHEBI:49033 methionine S-oxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49033 GO:1904546 obsolete negative regulation of cAMP-dependent protein kinase activity involved in negative regulation of glucose mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904546 negative regulation of cyclic AMP-dependent protein kinase activity involved in downregulation of glucose mediated signalling|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in negative regulation of glucose mediated signaling pathway|negative regulation of cAMP-dependent protein kinase activity involved in negative regulation of glucose mediated signalling|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in down-regulation of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase activity involved in down-regulation of glucose mediated signaling pathway|negative regulation of cAMP-dependent protein kinase activity involved in down-regulation of glucose mediated signalling|negative regulation of AMPK involved in negative regulation of glucose mediated signaling pathway|negative regulation of AMPK involved in down-regulation of glucose mediated signaling pathway|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in negative regulation of glucose mediated signalling|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in down-regulation of glucose mediated signaling pathway|negative regulation of PKA C involved in inhibition of glucose mediated signaling pathway|negative regulation of PKA involved in down regulation of glucose mediated signalling|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in inhibition of glucose mediated signaling pathway|negative regulation of cyclic AMP-dependent protein kinase activity involved in downregulation of glucose mediated signaling pathway|negative regulation of STK22 involved in inhibition of glucose mediated signaling pathway|negative regulation of protein kinase A activity involved in down regulation of glucose mediated signaling pathway|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in down-regulation of glucose mediated signalling|negative regulation of PKA C involved in down regulation of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in downregulation of glucose mediated signalling|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in negative regulation of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in inhibition of glucose mediated signaling pathway|negative regulation of cyclic AMP-dependent protein kinase activity involved in negative regulation of glucose mediated signaling pathway|negative regulation of cyclic AMP-dependent protein kinase activity involved in down-regulation of glucose mediated signaling pathway|negative regulation of STK22 involved in down regulation of glucose mediated signalling|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in downregulation of glucose mediated signalling|negative regulation of protein kinase A activity involved in inhibition of glucose mediated signaling pathway|negative regulation of protein kinase A activity involved in inhibition of glucose mediated signalling|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in inhibition of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase activity involved in downregulation of glucose mediated signaling pathway|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in downregulation of glucose mediated signaling pathway|negative regulation of STK22 involved in down regulation of glucose mediated signaling pathway|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in down-regulation of glucose mediated signalling|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in negative regulation of glucose mediated signalling|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in down regulation of glucose mediated signaling pathway|negative regulation of cyclic AMP-dependent protein kinase activity involved in inhibition of glucose mediated signaling pathway|negative regulation of PKA C involved in down regulation of glucose mediated signaling pathway|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in down-regulation of glucose mediated signaling pathway|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in downregulation of glucose mediated signaling pathway|negative regulation of protein kinase A activity involved in down regulation of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in negative regulation of glucose mediated signaling pathway|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in inhibition of glucose mediated signalling|negative regulation of STK22 involved in inhibition of glucose mediated signalling|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in down regulation of glucose mediated signalling|negative regulation of AMPK involved in negative regulation of glucose mediated signalling|negative regulation of PKA involved in down regulation of glucose mediated signaling pathway|negative regulation of AMPK involved in down-regulation of glucose mediated signalling|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in down regulation of glucose mediated signaling pathway|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in down-regulation of glucose mediated signaling pathway|negative regulation of PKA C involved in inhibition of glucose mediated signalling|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in negative regulation of glucose mediated signaling pathway|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in down regulation of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase activity involved in inhibition of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase activity involved in inhibition of glucose mediated signaling pathway|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in downregulation of glucose mediated signaling pathway|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in inhibition of glucose mediated signalling|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in inhibition of glucose mediated signaling pathway|negative regulation of PKA involved in inhibition of glucose mediated signalling|negative regulation of PKA involved in down-regulation of glucose mediated signalling|negative regulation of PKA involved in negative regulation of glucose mediated signalling|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in down regulation of glucose mediated signaling pathway|negative regulation of AMPK involved in down regulation of glucose mediated signaling pathway|negative regulation of cAMP-dependent protein kinase activity involved in down regulation of glucose mediated signaling pathway|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in inhibition of glucose mediated signaling pathway|negative regulation of cyclic AMP-dependent protein kinase activity involved in down regulation of glucose mediated signalling|negative regulation of cyclic AMP-dependent protein kinase activity involved in inhibition of glucose mediated signalling|negative regulation of AMPK involved in downregulation of glucose mediated signaling pathway|negative regulation of AMPK involved in inhibition of glucose mediated signalling|negative regulation of PKA C involved in down-regulation of glucose mediated signalling|negative regulation of protein kinase A activity involved in downregulation of glucose mediated signalling|negative regulation of PKA C involved in negative regulation of glucose mediated signalling|negative regulation of STK22 involved in down-regulation of glucose mediated signalling|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in inhibition of glucose mediated signaling pathway|negative regulation of cyclic AMP-dependent protein kinase activity involved in down regulation of glucose mediated signaling pathway|negative regulation of STK22 involved in negative regulation of glucose mediated signalling|negative regulation of PKA involved in downregulation of glucose mediated signaling pathway|negative regulation of cAMP-dependent protein kinase activity involved in down regulation of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in inhibition of glucose mediated signalling|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in down regulation of glucose mediated signalling|negative regulation of STK22 involved in downregulation of glucose mediated signalling|negative regulation of protein kinase A activity involved in down-regulation of glucose mediated signaling pathway|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in down regulation of glucose mediated signaling pathway|negative regulation of protein kinase A activity involved in negative regulation of glucose mediated signaling pathway|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in inhibition of glucose mediated signalling|negative regulation of PKA C involved in downregulation of glucose mediated signalling|negative regulation of protein kinase A activity involved in down-regulation of glucose mediated signalling|negative regulation of PKA C involved in downregulation of glucose mediated signaling pathway|negative regulation of protein kinase A activity involved in negative regulation of glucose mediated signalling|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in downregulation of glucose mediated signalling|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in down regulation of glucose mediated signalling|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in down-regulation of glucose mediated signalling|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in negative regulation of glucose mediated signalling|negative regulation of STK22 involved in downregulation of glucose mediated signaling pathway|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in down regulation of glucose mediated signaling pathway|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in downregulation of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in down-regulation of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in negative regulation of glucose mediated signalling|negative regulation of PKA involved in downregulation of glucose mediated signalling|negative regulation of STK22 involved in down-regulation of glucose mediated signaling pathway|negative regulation of STK22 involved in negative regulation of glucose mediated signaling pathway|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in down regulation of glucose mediated signalling|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in down-regulation of glucose mediated signaling pathway|negative regulation of AMPK involved in inhibition of glucose mediated signaling pathway|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in negative regulation of glucose mediated signaling pathway|negative regulation of PKA C involved in negative regulation of glucose mediated signaling pathway|negative regulation of PKA C involved in down-regulation of glucose mediated signaling pathway|negative regulation of protein kinase A activity involved in downregulation of glucose mediated signaling pathway|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in downregulation of glucose mediated signaling pathway|negative regulation of cAMP-dependent protein kinase activity involved in downregulation of glucose mediated signalling|negative regulation of AMPK involved in downregulation of glucose mediated signalling|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in downregulation of glucose mediated signalling|negative regulation of cyclic AMP-dependent protein kinase activity involved in down-regulation of glucose mediated signalling|negative regulation of cyclic AMP-dependent protein kinase activity involved in negative regulation of glucose mediated signalling|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in negative regulation of glucose mediated signaling pathway|negative regulation of AMPK involved in down regulation of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in downregulation of glucose mediated signaling pathway|negative regulation of PKA involved in inhibition of glucose mediated signaling pathway|negative regulation of PKA involved in down-regulation of glucose mediated signaling pathway|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in down-regulation of glucose mediated signaling pathway|negative regulation of PKA involved in negative regulation of glucose mediated signaling pathway OBSOLETE. Any negative regulation of cAMP-dependent protein kinase activity that is involved in negative regulation of glucose mediated signaling pathway. CHEBI:49032 L-methionine (R)-S-oxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49032 CHEBI:49035 D-methionine (R)-S-oxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49035 GO:1904544 positive regulation of free ubiquitin chain polymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904544 up regulation of free ubiquitin chain polymerization|activation of free ubiquitin chain polymerization|up-regulation of free ubiquitin chain polymerization|upregulation of free ubiquitin chain polymerization Any process that activates or increases the frequency, rate or extent of free ubiquitin chain polymerization. CHEBI:49034 D-methionine S-oxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49034 GO:1904543 negative regulation of free ubiquitin chain polymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904543 down-regulation of free ubiquitin chain polymerization|inhibition of free ubiquitin chain polymerization|down regulation of free ubiquitin chain polymerization|downregulation of free ubiquitin chain polymerization Any process that stops, prevents or reduces the frequency, rate or extent of free ubiquitin chain polymerization. GO:1904542 regulation of free ubiquitin chain polymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904542 Any process that modulates the frequency, rate or extent of free ubiquitin chain polymerization. CHEBI:49036 D-methionine (S)-S-oxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49036 GO:1904552 regulation of chemotaxis to arachidonic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904552 Any process that modulates the frequency, rate or extent of chemotaxis to arachidonic acid. GO:1904551 cellular response to arachidonic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904551 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arachidonic acid stimulus. GO:1904550 response to arachidonic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904550 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arachidonic acid stimulus. CHEBI:25091 luteolin O-glucuronoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25091 CL:0002612 neuron of the ventral spinal cord biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002612 A neuron of the ventral spinal cord. CL:0002611 neuron of the dorsal spinal cord biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002611 A CNS neuron of the dorsal spinal cord. GO:0003989 acetyl-CoA carboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003989 EC:6.4.1.2|MetaCyc:ACETYL-COA-CARBOXYLTRANSFER-RXN|Reactome:R-HSA-200555|RHEA:11308|Reactome:R-HSA-8876889|Reactome:R-HSA-75851 acetyl coenzyme A carboxylase activity|acetyl-CoA:carbon-dioxide ligase (ADP-forming) Catalysis of the reaction: ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA. CHEBI:64669 2-hydroxy-3-methylbutyrate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64669 CHEBI:64668 geranylgeranyl-chlorophyll a biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64668 CL:1000050 lateral line nerve glial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000050 CHEBI:64672 differentiation-inducing factor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64672 CHEBI:64670 EC 1.8.1.9 (thioredoxin reductase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64670 CHEBI:64676 CDP-N,N-dimethylethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64676 CHEBI:64675 2,6-dioxo-6-phenylhexa-3-enoate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64675 CHEBI:64674 1,2-diacyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64674 CHEBI:64673 fumigaclavine C biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64673 CHEBI:64678 anthracycline cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64678 CHEBI:64677 daunorubicin(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64677 CL:1000042 forebrain neuroblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000042 CHEBI:74006 1-archaetidyl-1D-myo-inositol 3-phosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74006 CHEBI:74005 8-desmethylnovobiocic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74005 CHEBI:74008 3-O-phospho-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)]n-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-ditrans,octacis-undecaprenol(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74008 GO:0052902 spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052902 EC:1.5.3.17|EC:1.5.3.13|KEGG_REACTION:R09077|MetaCyc:RXN-10461|MetaCyc:RXN-12089|RHEA:25808 N(1)-acetylpolyamine oxidase activity|polyamine oxidase activity|non-specific polyamine oxidase activity Catalysis of the reaction: H(2)O + O(2) + spermidine = 3-aminopropanal + H(2)O(2) + putrescine. GO:0052901 spermine:oxygen oxidoreductase (spermidine-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052901 EC:1.5.3.17|EC:1.5.3.16|MetaCyc:RXN-9015|RHEA:25804|EC:1.5.3.13|Reactome:R-HSA-141341|MetaCyc:1.5.3.17-RXN|KEGG_REACTION:R09076 N(1)-acetylpolyamine oxidase activity|polyamine oxidase activity|non-specific polyamine oxidase activity|spermine oxidase activity Catalysis of the reaction: H(2)O + O(2) + spermine = 3-aminopropanal + H(2)O(2) + spermidine. CHEBI:74009 3-O-methylphospho-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)]n-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-ditrans,octacis-undecaprenol(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74009 GO:0052900 spermine oxidase (propane-1,3-diamine-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052900 EC:1.5.3.14|RHEA:25824|MetaCyc:RXN-6421 polyamine oxidase (propane-1,3-diamine-forming) activity Catalysis of the reaction: H(2)O + O(2) + spermine = 1,3-diaminopropane + H(2)O(2) + N-(3-aminopropyl)-4-aminobutanal. GO:0052906 tRNA (guanine(37)-N(1))-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052906 RHEA:36899|EC:2.1.1.228|MetaCyc:RXN-12458 tRNA-(N(1)G37) methyltransferase activity|transfer RNA (m(1)G(37)) methyltransferase activity|tRNA (m(1)G(37)) methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + guanine(37) in tRNA = N(1)-methylguanine(37) in tRNA + S-adenosyl-L-homocysteine. CHEBI:64683 1-acyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64683 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052905 RHEA:43156|MetaCyc:RXN-12459|EC:2.1.1.221 tRNA(m(1)G(9)/m(1)A(9))-methyltransferase activity|tRNA (guanine-N(1)-)-methyltransferase activity|tRNA m(1)G(9)-methyltransferase activity|tRNA m(1)G(9) Mtase activity|tRNA(m(1)G(9)/m(1)A(9))Mtase activity Catalysis of the reaction: S-adenosyl-L-methionine + guanine(9) in tRNA = N(1)-methylguanine(9) in tRNA + S-adenosyl-L-homocysteine. CHEBI:15709 xanthotoxol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15709 GO:0052904 N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052904 EC:1.5.3.17|MetaCyc:RXN-12091|EC:1.5.3.13|RHEA:25812|KEGG_REACTION:R09074|Reactome:R-HSA-141348|Reactome:R-HSA-141351|MetaCyc:RXN-9942 N(1)-acetylpolyamine oxidase activity|polyamine oxidase activity|non-specific polyamine oxidase activity Catalysis of the reaction: H(2)O + N(1)-acetylspermidine + O(2) = 3-acetamidopropanal + H(2)O(2) + putrescine. GO:0052903 N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052903 MetaCyc:RXN-9940|EC:1.5.3.17|EC:1.5.3.13|MetaCyc:RXN-12090|KEGG_REACTION:R03899|RHEA:25800 N(1)-acetylpolyamine oxidase activity|polyamine oxidase activity|non-specific polyamine oxidase activity Catalysis of the reaction: H(2)O + N(1)-acetylspermine + O(2) = 3-acetamidopropanal + H(2)O(2) + spermidine. CHEBI:64687 2,6-dioxo-6-phenylhexa-3-enoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64687 CHEBI:15705 L-alpha-amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15705 GO:0052909 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052909 RHEA:42780|MetaCyc:RXN-11634|EC:2.1.1.183 M(6)(2)A dimethylase activity Catalysis of the reaction: 4 S-adenosyl-L-methionine + adenine(1779)/adenine(1780) in 18S rRNA = 4 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(1779)/N(6)-dimethyladenine(1780) in 18S rRNA. CHEBI:64686 7-formamidino-7-deazaguanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64686 GO:0052908 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052908 RHEA:19609|MetaCyc:RXN-11633|EC:2.1.1.182 S-adenosylmethionine-6-N',N'-adenosyl (rRNA) dimethyltransferase activity Catalysis of the reaction: 4 S-adenosyl-L-methionine + adenine(1518)/adenine(1519) in 16S rRNA = 4 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(1518)/N(6)-dimethyladenine(1519) in 16S rRNA. CHEBI:15708 trans-aconitate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15708 GO:0052907 23S rRNA (adenine(1618)-N(6))-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052907 RHEA:16497|KEGG_REACTION:R07232|MetaCyc:RXN-11596|EC:2.1.1.181 M(6)A(1618) activity|rRNA large subunit methyltransferase F activity Catalysis of the reaction: S-adenosyl-L-methionine + adenine(1618) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(1618) in 23S rRNA. CHEBI:64684 7-formamidino-7-deazaguanine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64684 CHEBI:15707 2,6-dioxo-6-phenylhexanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15707 CHEBI:15702 terephthalic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15702 CHEBI:15704 6-alkylamino-7-beta-D-glucosylpurine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15704 CHEBI:64689 mycophenolic acid O-acyl-glucuronide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64689 CHEBI:15703 alpha-maltose 6'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15703 CHEBI:64688 artemisinic aldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64688 CHEBI:15700 dTDP-alpha-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15700 CL:1000073 spinal cord radial glial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000073 CHEBI:74000 1-palmitoyl-2-palmitoleoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74000 CHEBI:74001 1-O-octadecyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74001 CHEBI:74004 CDP-2,3-bis-(O-phytanyl)-sn-glycerol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74004 GO:0052913 16S rRNA (guanine(966)-N(2))-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052913 EC:2.1.1.171|MetaCyc:RXN0-6515|RHEA:23548|KEGG_REACTION:R07234 Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(966) in 16S rRNA = N(2)-methylguanosine(966) in 16S rRNA + S-adenosyl-L-homocysteine. GO:0052912 23S rRNA (guanine(748)-N(1))-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052912 EC:2.1.1.188|MetaCyc:RXN-11599|RHEA:42904|KEGG_REACTION:R07233 23S rRNA m(1)G(748) methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + guanine(748) in 23S rRNA = N(1)-methylguanine(748) in 23S rRNA + S-adenosyl-L-homocysteine. GO:0052911 23S rRNA (guanine(745)-N(1))-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052911 EC:2.1.1.187|MetaCyc:RXN-11573|RHEA:42900|KEGG_REACTION:R07233 ribosomal ribonucleate guanine 1-methyltransferase activity|S-adenosyl-L-methionine:rRNA (guanine-1-N-)-methyltransferase activity|rlmA(I) methyltransferase activity|ribosomal RNA(m(1)G)-methylase activity|23S rRNA m(1)G(745) methyltransferase activity|rRNA(m(1)G)methylase activity Catalysis of the reaction: S-adenosyl-L-methionine + guanine(745) in 23S rRNA = N(1)-methylguanine(745) in 23S rRNA + S-adenosyl-L-homocysteine. GO:0052910 23S rRNA (adenine(2085)-N(6))-dimethyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052910 MetaCyc:RXN-11597|EC:2.1.1.184|RHEA:42784 rRNA methyltransferase ermC' activity|ermC 23S rRNA methyltransferase activity|rRNA:m(6)A methyltransferase ermC' activity Catalysis of the reaction: 2 S-adenosyl-L-methionine + adenine(2085) in 23S rRNA = 2 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(2085) in 23S rRNA. GO:0052917 dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichol alpha-1,6-mannosyltransferase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052917 KEGG_REACTION:R06260|EC:2.4.1.260|MetaCyc:RXN-5468|RHEA:29535 dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|dolichyl-P-mannose:Man(7)GlcNAc(2)-PP-dolichyl mannosyltransferase activity|dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity Catalysis of the addition of mannose to dolichyl-pyrophosphate Man7GlcNAc2 (also written as Man7GlcNAc2-PP-Dol) in alpha-(1->6) linkage, producing Man8GlcNAc2-PP-Dol. CHEBI:64694 3,4-dihydroxy-5-polyprenylbenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64694 GO:0052916 23S rRNA (guanine(1835)-N(2))-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052916 MetaCyc:RXN-11635|EC:2.1.1.174|RHEA:42744|KEGG_REACTION:R07234 Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(1835) in 23S rRNA = N(2)-methylguanosine(1835) in 23S rRNA + S-adenosyl-L-homocysteine. CHEBI:64693 (3R)-3-methyl-D-ornithine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64693 GO:0052915 23S rRNA (guanine(2445)-N(2))-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052915 EC:2.1.1.173|MetaCyc:RXN-11574|RHEA:42740|KEGG_REACTION:R07234 Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(2445) in 23S rRNA = N(2)-methylguanosine(2445) in 23S rRNA + S-adenosyl-L-homocysteine. CHEBI:64692 N(6)-[(3R)-3-methyl-D-ornithyl]-L-lysine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64692 GO:0052914 16S rRNA (guanine(1207)-N(2))-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052914 MetaCyc:RXN-11576|EC:2.1.1.172|RHEA:42736|KEGG_REACTION:R07234 M(2)G1207 methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(1207) in 16S rRNA = N(2)-methylguanosine(1207) in 16S rRNA + S-adenosyl-L-homocysteine. CHEBI:64691 (11R)-dihydroartemisinic aldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64691 GO:0052919 aliphatic (R)-hydroxynitrile lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052919 EC:4.1.2.46 (R)-hydroxynitrile lyase activity|(R)-oxynitrilase activity|(R)-HNL activity Catalysis of the reaction: an aliphatic (R)-hydroxynitrile = an aliphatic aldehyde or ketone + hydrogen cyanide. GO:0052918 dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052918 KEGG_REACTION:R06261|EC:2.4.1.261|MetaCyc:RXN-5469|RHEA:29539 Catalysis of the reaction: alpha-D-man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->6))-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl D-mannosyl phosphate = H(+) + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->6))-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate. CHEBI:74011 (11Z)-3-oxoicosa-11-enoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74011 CHEBI:74010 alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)]n-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-ditrans,octacis-undecaprenol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74010 CHEBI:74012 (11Z,14Z)-3-oxoicosa-11,14-dienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74012 GO:0052920 (2R)-2-hydroxy-2-methylbutanenitrile lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052920 KEGG_REACTION:R09358|MetaCyc:RXN-11733|RHEA:28170|EC:4.1.2.46 Catalysis of the reaction: (2R)-2-hydroxy-2-methylbutanenitrile = butan-2-one + hydrogen cyanide. CHEBI:74028 beta-D-Gal-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74028 GO:0052924 all-trans-nonaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052924 EC:2.5.1.85|RHEA:27594|KEGG_REACTION:R09251|MetaCyc:RXN-11486 solanesyl diphosphate synthase activity|nonaprenyl diphosphate synthase activity|solanesyl diphosphate synthetase activity Catalysis of the reaction: geranylgeranyl diphosphate + 5 isopentenyl diphosphate = 5 diphosphate + all-trans-nonaprenyl diphosphate. GO:0052923 all-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052923 EC:2.5.1.84|RHEA:27563|KEGG_REACTION:R09250|MetaCyc:TRANS-OCTAPRENYLTRANSTRANSFERASE-RXN SPP synthase activity|solPP synthase activity|nonaprenyl diphosphate synthase activity|solanesyl-diphosphate synthase activity|SPP-synthase activity|solanesyl diphosphate synthetase activity Catalysis of the reaction: geranyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + all-trans-nonaprenyl diphosphate. GO:0052922 hexaprenyl diphosphate synthase (geranylgeranyl-diphosphate specific) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052922 RHEA:27555|EC:2.5.1.82|KEGG_REACTION:R09246|MetaCyc:RXN-11485 hexaprenyl pyrophosphate synthetase activity|(all-trans)-hexaprenyl-diphosphate synthase activity|(all-E) hexaprenyl diphosphate synthase activity|hexaprenyl diphosphate synthase activity Catalysis of the reaction: geranylgeranyl diphosphate + 2 isopentenyl diphosphate = 2 diphosphate + all-trans-hexaprenyl diphosphate. GO:0052921 acetone-cyanohydrin acetone-lyase (cyanide-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052921 KEGG_REACTION:R01553|MetaCyc:ACETONE-CYANHYDRIN-LYASE-RXN|EC:4.1.2.46|RHEA:11932 Catalysis of the reaction: acetone cyanohydrin = hydrogen cyanide + acetone. GO:0052928 CTP:3'-cytidine-tRNA cytidylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052928 EC:2.7.7.72|KEGG_REACTION:R09384 Catalysis of the reaction: a tRNA with a 3' cytidine + CTP = a tRNA with a 3' CC end + diphosphate. GO:0052927 CTP:tRNA cytidylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052927 EC:2.7.7.72|KEGG_REACTION:R09383 Catalysis of the reaction: a tRNA precursor + CTP = a tRNA with a 3' cytidine end + diphosphate. GO:0052926 dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052926 KEGG_REACTION:R06259|EC:2.4.1.259|RHEA:29531|MetaCyc:RXN-5467 dolichylphosphomannose-dependent ALG9 mannosyltransferase activity Catalysis of the reaction: alpha-D-man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->3)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl D-mannosyl phosphate = H(+) + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate. GO:0052925 dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052925 RHEA:29527|KEGG_REACTION:R06258|EC:2.4.1.258|MetaCyc:RXN-5466 man(5)GlcNAc(2)-PP-Dol mannosyltransferase activity|dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase activity Catalysis of the reaction: an alpha-D-man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl D-mannosyl phosphate = H(+) + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->3)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate. GO:0052929 ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052929 KEGG_REACTION:R09386|EC:2.7.7.72 ATP:tRNA adenylyltransferase activity|ATP:3'-CC-tRNA adenylyltransferase activity Catalysis of the reaction: a tRNA with a 3' CC end + ATP = a tRNA with a 3' CCA end + diphosphate. CHEBI:74020 diosgenin 3-O-beta-D-glucoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74020 CHEBI:74023 dioscin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74023 CHEBI:74026 26-desglucoprotodioscin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74026 GO:0052931 ethanol cytochrome-c oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052931 KEGG_REACTION:R09127|EC:1.1.2.7 ethanol dehydrogenase activity|ethanol dehydrogenase (cytochrome c) activity Catalysis of the reaction: ethanol + 2 cytochrome c(L) = acetaldehyde + 2 reduced cytochrome c(L) + 2 H+. GO:0052930 methanol ferricytochrome-c oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052930 MetaCyc:RXN-2861|RHEA:51008|KEGG_REACTION:R01146|EC:1.1.2.7 methanol dehydrogenase activity|methanol dehydrogenase (cytochrome c) activity Catalysis of the reaction: methanol + 2 ferricytochrome c = formaldehyde + 2 ferrocytochrome c + 2 H+. CHEBI:74038 beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74038 GO:0052935 ethanol:cytochrome c oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052935 RHEA:51020|EC:1.1.2.8|KEGG_REACTION:R05198 ethanol dehydrogenase (cytochrome c) activity Catalysis of the reaction: ethanol + 2 cytochrome c = 2 reduced cytochrome c + acetaldehyde. GO:0052934 alcohol dehydrogenase (cytochrome c) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052934 MetaCyc:RXN-11333|EC:1.1.2.8 quinoprotein alcohol dehydrogenase activity|alcohol:cytochrome c oxidoreductase activity Catalysis of the reaction: primary alcohol + 2 cytochrome c = 2 reduced cytochrome c + an aldehyde + 2 H+. UBERON:4000170 median fin skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_4000170 unpaired fin skeleton|axial fin skeleton Postcranial axial skeleton that is unpaired and located on the sagittal plane of the organism. GO:0052933 alcohol dehydrogenase (cytochrome c(L)) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052933 MetaCyc:RXN-11332|RHEA:51004|EC:1.1.2.7 alcohol:cytochrome c(L) oxidoreductase activity Catalysis of the reaction: primary alcohol + 2 cytochrome c(L) = 2 reduced cytochrome c(L) + an aldehyde + 2 H+. GO:0052932 2-chloroethanol cytochrome-c oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052932 KEGG_REACTION:R09128|EC:1.1.2.7 2-chloroethanol dehydrogenase activity|2-chloroethanol dehydrogenase (cytochrome c) activity Catalysis of the reaction: 2-chloroethanol + 2 cytochrome c(L) = chloroacetaldehyde + 2 reduced cytochrome c(L). GO:0052936 2-chloroethanol:cytochrome c oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052936 RHEA:55947|KEGG_REACTION:R05285 Catalysis of the reaction: 2-chloroethanol + 2 cytochrome c = chloroacetaldehyde + 2 reduced cytochrome c. CL:1000001 retrotrapezoid nucleus neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000001 CHEBI:74030 3'-N-debenzoyl-2'-deoxytaxol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74030 CHEBI:74033 beta-D-Glc-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74033 CHEBI:74032 beta-D-Gal-(1->4)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74032 UBERON:4000168 dorsal fin skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_4000168 Median fin skeleton located on the dorsal surface of the organism. CHEBI:74035 small nuclear RNA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74035 CHEBI:74034 alpha-linolenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74034 CHEBI:74037 (11Z)-3-oxoicosa-11-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74037 CHEBI:74036 alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74036 UBERON:4000164 caudal fin biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_4000164 nageoire caudale|tail|uroptérygie|uroptère|tail fin The caudal fin is the most posterior median fin. It is composed of a complex of modified centra and modified neural and hemal arches and spines. UBERON:4000163 anal fin biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_4000163 nageoire anale|proctoptérygie|proctoptère Median fin that is located posterior to the anus. UBERON:4000162 median fin biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_4000162 nageoire impaire|périssoptérygie Fin that is an unpaired fin located in the sagittal plane of the organism. CHEBI:156473 cyclobutanes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_156473 CHEBI:74040 alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74040 CHEBI:74042 2-[(3S)-3-amino-3-carboxypropyl]-L-histidine dizwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74042 CHEBI:74041 alpha-D-Gal-(1->3)-[alpha-L-Fuc-(1->2)]-beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74041 CHEBI:74043 2-[(3S)-3-amino-3-carboxypropyl]-L-histidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74043 CHEBI:74045 GDP-4-amino-4,6-dideoxy-alpha-D-mannose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74045 CL:0002681 kidney cortical cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002681 CL:0002680 PP cell of intestine biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002680 A PP cell found in intestine. CHEBI:74047 GDP-N-acetyl-alpha-D-perosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74047 CL:0012001 neuron of the forebrain biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0012001 forebrain neuron A CNS neuron of the forebrain. CL:0012000 astrocyte of the forebrain biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0012000 forebrain astrocyte An astrocyte of the forebrain. CHEBI:156461 5'-(N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_156461 CL:1000022 mesonephric nephron tubule epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000022 CHEBI:74050 CDP-2,3-bis-(O-phytanyl)-sn-glycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74050 CHEBI:74054 (11Z,14Z,17Z)-3-oxoicosatrienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74054 UBERON:0036654 wall of lateral ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036654 UBERON:0036657 wall of fourth ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036657 UBERON:0036656 wall of third ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036656 CHEBI:15647 leukotriene B4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15647 CHEBI:15646 20-hydroxy-leukotriene B4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15646 CHEBI:15649 3,6,9-trihydroxypterocarpan biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15649 CHEBI:15648 (6aR,11aR)-3,9-dihydroxypterocarpan biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15648 CHEBI:15642 4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15642 CHEBI:15645 (6S)-6-hydroxyhyoscyamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15645 CHEBI:40611 adamantanone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_40611 CHEBI:15644 (S)-NADHX(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15644 CHEBI:15641 5-methyltetrahydrofolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15641 CHEBI:15640 5-formyltetrahydrofolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15640 UBERON:0036661 wall of ventricular system of brain biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036661 CHEBI:15639 5-formimidoyltetrahydrofolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15639 CHEBI:15636 (6R)-5,10-methylenetetrahydrofolate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15636 UBERON:0036658 wall of central canal of spinal cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036658 wall of central canal CHEBI:15635 (6S)-5,6,7,8-tetrahydrofolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15635 CHEBI:15638 (6R)-5,10-methenyltetrahydrofolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15638 CHEBI:15637 10-formyltetrahydrofolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15637 CHEBI:15632 5(S)-HPETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15632 CHEBI:15631 (5Z,9E,14Z)-(8xi,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15631 CHEBI:15634 10-formyldihydrofolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15634 CHEBI:15633 dihydrofolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15633 CHEBI:15630 (5Z,9E,12S,14Z)-8,11,12-trihydroxyicosa-5,9,14-trienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15630 CHEBI:15669 trans-cinnamate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15669 CHEBI:64603 diadenosyl polyphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64603 CHEBI:15668 (1E)-4-oxobut-1-ene-1,2,4-tricarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15668 CHEBI:64602 dermatan sulfate proteoglycan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64602 CHEBI:64600 C21-steroid hormone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64600 CHEBI:15665 (4-hydroxyphenyl)acetaldehyde oxime biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15665 CHEBI:64607 Fe4S4 iron-sulfur cluster biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64607 CHEBI:64606 Fe3S4 iron-sulfur cluster biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64606 CHEBI:15664 (2E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15664 CHEBI:15667 (Z)-(4-hydroxyphenyl)acetaldehyde oxime biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15667 CHEBI:64604 diphosphoinositol polyphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64604 CHEBI:15666 (E)-(4-hydroxyphenyl)acetaldehyde oxime biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15666 CHEBI:543745 3',4',5'-O-trimethyltricetin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_543745 CHEBI:15661 (2E)-2-(methoxycarbonylmethyl)but-2-enedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15661 CHEBI:15660 (Z)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15660 CHEBI:64609 dinitrosyl-iron complex biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64609 CHEBI:15663 (2E)-3-(methoxycarbonyl)pent-2-enedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15663 CHEBI:15662 (2E)-2,6-dimethylocta-2,7-diene-1,6-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15662 CHEBI:64608 GDP-fucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64608 UBERON:0012651 mucosa of gastroduodenal junction biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012651 gastroduodenal mucosa A mucosa that is part of a gastroduodenal junction. UBERON:0012650 gastroduodenal junction biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012650 A anatomical junction that connects a stomach and connects a duodenum. CHEBI:64610 tenocyclidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64610 CHEBI:15658 7(S),8(S)-DiHODE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15658 CHEBI:15657 (11S)-11-hydroperoxylinoleic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15657 CHEBI:64612 1,2-diacyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64612 CHEBI:15659 (E)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15659 CHEBI:64611 ether lipid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64611 CHEBI:64618 phosphagen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64618 CHEBI:15653 (9Z,13S,15Z)-12,13-epoxyoctadeca-9,11,15-trienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15653 CHEBI:64616 apiogalacturonan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64616 CHEBI:64615 triacyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64615 CHEBI:15655 13(S)-HPODE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15655 CHEBI:15650 leukotriene E4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15650 CHEBI:15652 5'-xanthylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15652 CHEBI:15651 leukotriene A4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15651 CHEBI:15607 (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15607 CHEBI:64621 quercetin O-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64621 CHEBI:15606 (2S)-flavanone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15606 CHEBI:64620 purine ribonucleoside bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64620 CHEBI:15609 N-(aminomethyl)urea biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15609 CHEBI:15608 (2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15608 CHEBI:15603 L-leucine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15603 CHEBI:15602 (2S)-2-[(R)-1-carboxyethylamino]pentanoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15602 CHEBI:64624 microcin B17 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64624 CHEBI:15605 (2S)-flavan-4-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15605 CHEBI:64623 saturated monocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64623 CHEBI:64622 reuteran biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64622 CHEBI:15604 (3R)-beta-leucine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15604 CHEBI:64629 2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64629 CHEBI:64628 somatostatin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64628 CHEBI:15601 (2R,4S)-2,4-diaminopentanoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15601 CHEBI:64627 microcin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64627 CHEBI:64626 teichuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64626 CHEBI:15600 (+)-catechin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15600 CHEBI:64632 indoleacetic acid amide conjugate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64632 CHEBI:64631 indoleacetic acid conjugate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64631 CHEBI:64634 kaempferol O-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64634 CHEBI:64633 indoleacetic acid ester conjugate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64633 CHEBI:64637 O-polysaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64637 CHEBI:64643 N(6)-[(3R)-3-methyl-D-ornithyl]-L-lysine(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64643 CHEBI:15629 8(R)-HPETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15629 CHEBI:64642 (3R)-3-methyl-D-ornithine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64642 CHEBI:15628 15(S)-HPETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15628 CHEBI:64641 divalent inorganic cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64641 CHEBI:64640 hypusine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64640 CHEBI:15625 S-adenosylmethioninamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15625 CHEBI:15624 (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15624 CHEBI:64645 amyloid-beta biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64645 CHEBI:15627 thromboxane A2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15627 CHEBI:15626 12(S)-HPETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15626 CHEBI:15621 (4-hydroxyphenyl)acetaldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15621 CHEBI:15620 N-ethylglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15620 CHEBI:15623 3-deoxy-D-glycero-hexo-2,5-diulosonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15623 CHEBI:15622 2,3-diketogulonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15622 CHEBI:64648 enniatin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64648 CHEBI:15618 (3Z)-phycoerythrobilin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15618 CHEBI:64654 guanosine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64654 CHEBI:15617 (2R,3Z)-phycocyanobilin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15617 CHEBI:15619 (3Z)-phytochromobilin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15619 CHEBI:15614 (S)-3-methyl-2-oxovaleric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15614 CHEBI:15613 (3S)-3,6-diaminohexanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15613 CHEBI:64656 cytidine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64656 CHEBI:15616 (3S,5S)-3,5-diaminohexanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15616 CHEBI:15615 (3S,4S)-3-hydroxytetradecane-1,3,4-tricarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15615 CHEBI:15610 gibberellin A12 aldehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15610 CHEBI:88609 trans-2-dodecene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88609 CHEBI:15611 sarcosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15611 CHEBI:49028 acetimidic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49028 CHEBI:50017 arsonous acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50017 CHEBI:50014 (R,R)-hydrobenzoin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50014 CHEBI:50018 glycosyloxyflavone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50018 CHEBI:49020 hormone antagonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49020 CHEBI:49022 beta-neuraminic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49022 CHEBI:25051 lipid As biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25051 CHEBI:49024 alpha-neuraminic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49024 CHEBI:49023 prostaglandin antagonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49023 CHEBI:49026 N-acetyl-alpha-neuraminic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49026 CHEBI:50013 hydrobenzoin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50013 CHEBI:50006 stilbene oxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50006 CHEBI:49017 3-methylthiopropanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49017 CHEBI:49016 3-(methylthio)propionate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49016 CHEBI:50004 cis-stilbene oxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50004 CHEBI:49019 3-methylthiopropanol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49019 CHEBI:49018 neuraminic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49018 CHEBI:50007 antimony coordination entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50007 CHEBI:49015 1-piperideine-6-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49015 CHEBI:49014 (S)-1-piperideine-6-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49014 PR:000036199 non-peptidyl modified amino-acid residue biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000036199 An organic group that results from covalent modification or chemical alteration to the backbone atoms of amino acid residues so that their peptide bond is altered but the C1 and alpha-N bond is uncleaved. PR:000036198 peptidyl modified amino-acid residue biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000036198 An amino-acid residue that results from covalent modification or chemical alteration to the side chain or backbone atoms such that the peptide bonds remain. CHEBI:49006 N-acetylcitrulline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49006 PR:000036194 eukaryotic protein biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000036194 Eukaryota protein A protein that is encoded in the genome of some Eukaryota. CHEBI:49008 (1R,6S)-1,6-dihydroxy-4-methylcyclohexa-2,4-diene-1-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49008 CHEBI:49007 D-citrulline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49007 CHEBI:25036 lignan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25036 CHEBI:49009 (1S,6R)-1,6-dihydroxy-4-methylcyclohexa-2,4-diene-1-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49009 CHEBI:40673 L-2-amino-3-oxobutanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_40673 CHEBI:49002 N-acetyl-L-citrulline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49002 CHEBI:49004 N-acetyl-LL-2,6-diaminopimelic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49004 CHEBI:49003 4-phospho-D-erythronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49003 CHEBI:25048 linolenic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25048 NCBITaxon:376913 Haplorrhini organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_376913 CHEBI:25040 limonene monoterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25040 CHEBI:25046 linear tetrapyrrole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25046 CHEBI:40666 1,6-anhydro-N-acetyl-beta-muramic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_40666 CHEBI:25017 leucine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25017 CHEBI:25016 lead atom biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_25016 CHEBI:25018 L-leucine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25018 CHEBI:15687 (S)-acetoin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15687 CHEBI:15686 (R)-acetoin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15686 CHEBI:40656 beta-D-allose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_40656 CHEBI:15689 2,3-dihydroxy-3-methylbutanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15689 CHEBI:15688 acetoin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15688 CHEBI:15683 (R)-10-hydroxyoctadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15683 CHEBI:15682 (N(omega)-L-arginino)succinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15682 CHEBI:15685 L-2-succinylamino-6-oxoheptanedioate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15685 CHEBI:15684 (R)-2,3-dihydroxy-3-methylbutanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15684 CHEBI:15681 alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15681 CHEBI:25029 leukotriene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25029 CHEBI:25022 leucomycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25022 CHEBI:15679 alpha-N-acetylneuraminyl-(2->6)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15679 CHEBI:15676 allantoin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15676 CHEBI:15675 (2R)-1-aminopropan-2-ol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15675 CHEBI:15678 (S)-(+)-allantoin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15678 CHEBI:15677 (R)-(-)-allantoin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15677 CHEBI:15672 D-tartaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15672 CHEBI:15671 L-tartaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15671 CHEBI:15674 2,3-dihydroxybutanedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15674 CHEBI:15673 meso-tartaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15673 CHEBI:15670 (E)-glutaconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15670 UBERON:0012615 umbilical smooth muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012615 A smooth muscle tissue that is part of a umbilical cord. CHEBI:8210 pimara-8(14),15-diene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_8210 CHEBI:25004 lactose phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25004 CHEBI:25002 lactosamines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25002 CHEBI:25000 lactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25000 CHEBI:15698 2'-deoxycytidine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15698 CHEBI:15699 L-homoserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15699 CHEBI:15694 (R)-S-lactoylglutathione biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15694 CHEBI:15693 aldose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15693 CHEBI:15696 beta-D-glucosyl-(1->4)-N-acetyl-D-glucosaminyl undecaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15696 CHEBI:15695 D-4-hydroxyphenylglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15695 CHEBI:15690 20-hydroxy-3-oxopregn-4-en-21-al biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15690 CHEBI:15692 3'-demethylstaurosporine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15692 CHEBI:8225 pinoresinol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_8225 UBERON:4000020 mineralized extracellular matrix biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_4000020 Extracellular matrix that is mineralized. GO:1904839 negative regulation of male germ-line stem cell asymmetric division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904839 inhibition of male germ-line stem cell asymmetric division|negative regulation of male germ-line stem cell renewal|down-regulation of male germ-line stem cell renewal|down-regulation of male germ-line stem cell asymmetric division|downregulation of male germ-line stem cell renewal|downregulation of male germ-line stem cell asymmetric division|down regulation of male germ-line stem cell renewal|down regulation of male germ-line stem cell asymmetric division|inhibition of male germ-line stem cell renewal Any process that stops, prevents or reduces the frequency, rate or extent of male germ-line stem cell asymmetric division. GO:1904838 regulation of male germ-line stem cell asymmetric division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904838 regulation of male germ-line stem cell renewal Any process that modulates the frequency, rate or extent of male germ-line stem cell asymmetric division. GO:1904837 beta-catenin-TCF complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904837 beta-catenin-TCF complex formation|beta-catenin/lymphoid enhancer binding factor complex assembly|beta-catenin/LEF complex formation|beta-catenin/T-cell factor complex formation|beta-catenin/T-cell factor complex assembly|beta-catenin/lymphoid enhancer binding factor complex formation|beta-catenin/LEF complex assembly The aggregation, arrangement and bonding together of a set of components to form a beta-catenin-TCF complex. GO:1904836 facioacoustic ganglion morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904836 facio-acoustic VII-VIII ganglion complex morphogenesis|facio-acoustic ganglion complex VII-VIII morphogenesis|facio-acoustic ganglion morphogenesis|facio-acoustic ganglion complex morphogenesis|acousticofacial ganglion morphogenesis|acoustico-facial VII-VIII ganglion complex morphogenesis The developmental process by which an acoustico-facial VII-VIII ganglion complex is generated and organized. GO:1904835 dorsal root ganglion morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904835 ganglion sensorium nervi spinalis morphogenesis|ganglion spinalis morphogenesis|spinal ganglion part of peripheral nervous system morphogenesis|posterior root ganglion morphogenesis|spinal ganglion morphogenesis|ganglion spinale morphogenesis|dorsal root ganglia morphogenesis|DRG morphogenesis|ganglion of dorsal root morphogenesis The developmental process by which a dorsal root ganglion is generated and organized. GO:1904834 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1904834 CHEBI:132129 (8S)-hepoxilin A3(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132129 GO:1904833 positive regulation of removal of superoxide radicals biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904833 positive regulation of removal of O2-|up regulation of removal of O2-|positive regulation of cellular detoxification of superoxide radicals|upregulation of removal of superoxide radicals|up regulation of removal of oxygen free radicals|up regulation of cellular detoxification of superoxide radicals|activation of removal of oxygen free radicals|positive regulation of removal of oxygen free radicals|upregulation of removal of O2-|up-regulation of removal of superoxide radicals|activation of removal of superoxide radicals|upregulation of cellular detoxification of superoxide radicals|up-regulation of removal of oxygen free radicals|activation of removal of O2-|up-regulation of removal of O2-|activation of cellular detoxification of superoxide radicals|up-regulation of cellular detoxification of superoxide radicals|up regulation of removal of superoxide radicals|upregulation of removal of oxygen free radicals Any process that activates or increases the frequency, rate or extent of removal of superoxide radicals. GO:1904832 negative regulation of removal of superoxide radicals biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904832 down regulation of removal of oxygen free radicals|down-regulation of cellular detoxification of superoxide radicals|negative regulation of cellular detoxification of superoxide radicals|down regulation of removal of superoxide radicals|inhibition of removal of superoxide radicals|downregulation of removal of oxygen free radicals|downregulation of removal of O2-|downregulation of cellular detoxification of superoxide radicals|down regulation of removal of O2-|down-regulation of removal of oxygen free radicals|negative regulation of removal of oxygen free radicals|inhibition of removal of O2-|down regulation of cellular detoxification of superoxide radicals|inhibition of cellular detoxification of superoxide radicals|inhibition of removal of oxygen free radicals|down-regulation of removal of superoxide radicals|negative regulation of removal of O2-|down-regulation of removal of O2-|downregulation of removal of superoxide radicals Any process that stops, prevents or reduces the frequency, rate or extent of removal of superoxide radicals. GO:1904831 positive regulation of aortic smooth muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904831 upregulation of aortic smooth muscle cell differentiation|up regulation of aortic smooth muscle cell differentiation|activation of aortic smooth muscle cell differentiation|up-regulation of aortic smooth muscle cell differentiation Any process that activates or increases the frequency, rate or extent of aortic smooth muscle cell differentiation. GO:1904830 negative regulation of aortic smooth muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904830 down regulation of aortic smooth muscle cell differentiation|downregulation of aortic smooth muscle cell differentiation|down-regulation of aortic smooth muscle cell differentiation|inhibition of aortic smooth muscle cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of aortic smooth muscle cell differentiation. CHEBI:132122 S-(2-methyl-1-oxobut-3-en-2-yl)glutathione biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132122 CHEBI:132124 1,4-benzoquinones biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132124 CHEBI:132123 1,2-benzoquinones biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132123 CHEBI:132125 2,4-didehydro-3-deoxy-L-rhamnonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132125 CHEBI:132128 (3R)-farnesyl-6-hydroxy-2,3,5-trimethyl-4-oxocyclohexa-1,5-diene-1-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132128 CHEBI:132127 hepoxilin A3(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132127 UBERON:4000013 mineralized skeletal tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_4000013 mineralized tissue Skeletal tissue that is mineralized. CHEBI:132120 resolvin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132120 UBERON:6002639 larval sense organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_6002639 larval sense organ Any sense organ that is part of some larva. CHEBI:8290 Poly(G) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_8290 GO:1904849 positive regulation of cell chemotaxis to fibroblast growth factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904849 up regulation of cell chemotaxis to fibroblast growth factor|activation of cell chemotaxis to fibroblast growth factor|up-regulation of cell chemotaxis to fibroblast growth factor|upregulation of cell chemotaxis to fibroblast growth factor Any process that activates or increases the frequency, rate or extent of cell chemotaxis to fibroblast growth factor. GO:1904848 negative regulation of cell chemotaxis to fibroblast growth factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904848 down-regulation of cell chemotaxis to fibroblast growth factor|inhibition of cell chemotaxis to fibroblast growth factor|down regulation of cell chemotaxis to fibroblast growth factor|downregulation of cell chemotaxis to fibroblast growth factor Any process that stops, prevents or reduces the frequency, rate or extent of cell chemotaxis to fibroblast growth factor. GO:1904847 regulation of cell chemotaxis to fibroblast growth factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904847 Any process that modulates the frequency, rate or extent of cell chemotaxis to fibroblast growth factor. GO:1904846 negative regulation of establishment of bipolar cell polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904846 downregulation of establishment of bipolar cell polarity|down regulation of establishment of bipolar cell polarity|inhibition of establishment of bipolar cell polarity|down-regulation of establishment of bipolar cell polarity Any process that stops, prevents or reduces the frequency, rate or extent of establishment of bipolar cell polarity. GO:1904845 cellular response to L-glutamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904845 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamine stimulus. GO:1904844 response to L-glutamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904844 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamine stimulus. GO:1904843 cellular response to nitroglycerin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904843 cellular response to nitroglycerine|cellular response to trinitroglycerin|cellular response to trinitroglycerol|cellular response to nitroglycerol Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitroglycerin stimulus. GO:1904842 response to nitroglycerin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904842 response to trinitroglycerol|response to nitroglycerol|response to nitroglycerine|response to trinitroglycerin Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitroglycerin stimulus. GO:1904841 TORC2 complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1904841 TOR complex 2 binding|TORC 2 complex binding|TORC2 binding|rapamycin and nutrient-insensitive TOR complex binding|mTORC2 binding Interacting selectively and non-covalently with a TORC2 complex. GO:1904840 positive regulation of male germ-line stem cell asymmetric division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904840 up regulation of male germ-line stem cell renewal|up regulation of male germ-line stem cell asymmetric division|upregulation of male germ-line stem cell renewal|upregulation of male germ-line stem cell asymmetric division|up-regulation of male germ-line stem cell renewal|activation of male germ-line stem cell renewal|up-regulation of male germ-line stem cell asymmetric division|activation of male germ-line stem cell asymmetric division|positive regulation of male germ-line stem cell renewal Any process that activates or increases the frequency, rate or extent of male germ-line stem cell asymmetric division. CHEBI:132137 (R)-demethyl-4-deoxygadusol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132137 CHEBI:132139 (R)-demethyl-4-deoxygadusol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132139 CHEBI:132131 3,5-dimethylorsellinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132131 CHEBI:132130 hydroxyquinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132130 GO:1904859 positive regulation of endothelial cell chemotaxis to vascular endothelial growth factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904859 up-regulation of endothelial cell chemotaxis to vascular endothelial growth factor|upregulation of endothelial cell chemotaxis to vascular endothelial growth factor|up regulation of endothelial cell chemotaxis to vascular endothelial growth factor|activation of endothelial cell chemotaxis to vascular endothelial growth factor Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis to vascular endothelial growth factor. GO:1904858 negative regulation of endothelial cell chemotaxis to vascular endothelial growth factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904858 down-regulation of endothelial cell chemotaxis to vascular endothelial growth factor|inhibition of endothelial cell chemotaxis to vascular endothelial growth factor|down regulation of endothelial cell chemotaxis to vascular endothelial growth factor|downregulation of endothelial cell chemotaxis to vascular endothelial growth factor Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis to vascular endothelial growth factor. GO:1904857 regulation of endothelial cell chemotaxis to vascular endothelial growth factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904857 Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis to vascular endothelial growth factor. GO:1904856 cytolytic granule lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1904856 cytolytic granule cytoplasmic membrane-bounded vesicle lumen|cytoplasmic membrane-enclosed vesicle lumen of cytolytic granule|cytoplasmic membrane-bounded vesicle lumen of cytolytic granule Any cytoplasmic membrane-bounded vesicle lumen that is part of a cytolytic granule. GO:1904855 proteasome regulatory particle binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1904855 19S regulatory particle binding|modulator complex binding|PA700-dependent proteasome activator binding|PA700 proteasome activator binding Interacting selectively and non-covalently with a proteasome regulatory particle. GO:1904854 proteasome core complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1904854 20S proteasome binding|PA28gamma-20S proteasome binding|macropain binding|20S core complex binding Interacting selectively and non-covalently with a proteasome core complex. GO:1904853 protein localization to ascospore wall biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904853 protein localisation to ascospore wall|protein localisation in ascospore wall|protein localization in ascospore wall A process in which a protein is transported to, or maintained in, a location within an ascospore wall. GO:1904852 trimethylamine-N-oxide reductase (cytochrome c) complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1904852 A protein complex which is capable of trimethylamine-N-oxide reductase (cytochrome c) activity. GO:1904851 positive regulation of establishment of protein localization to telomere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904851 upregulation of establishment of protein localization to chromosome, telomeric region|upregulation of establishment of protein localization to telomere|up regulation of establishment of protein localisation to telomere|activation of establishment of protein localisation to telomere|positive regulation of establishment of protein localisation to telomere|up regulation of establishment of protein localization to chromosome, telomeric region|activation of establishment of protein localization to chromosome, telomeric region|up regulation of establishment of protein localization to telomere|activation of establishment of protein localization to telomere|positive regulation of establishment of protein localization to chromosome, telomeric region|up-regulation of establishment of protein localisation to telomere|up-regulation of establishment of protein localization to chromosome, telomeric region|up-regulation of establishment of protein localization to telomere|upregulation of establishment of protein localisation to telomere Any process that activates or increases the frequency, rate or extent of establishment of protein localization to telomere. GO:1904850 negative regulation of establishment of protein localization to telomere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904850 downregulation of establishment of protein localisation to telomere|down regulation of establishment of protein localization to chromosome, telomeric region|down regulation of establishment of protein localization to telomere|downregulation of establishment of protein localization to chromosome, telomeric region|downregulation of establishment of protein localization to telomere|down-regulation of establishment of protein localisation to telomere|negative regulation of establishment of protein localisation to telomere|negative regulation of establishment of protein localization to chromosome, telomeric region|down-regulation of establishment of protein localization to chromosome, telomeric region|inhibition of establishment of protein localisation to telomere|down-regulation of establishment of protein localization to telomere|inhibition of establishment of protein localization to chromosome, telomeric region|inhibition of establishment of protein localization to telomere|down regulation of establishment of protein localisation to telomere Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization to telomere. GO:1904860 DNA synthesis involved in mitotic DNA replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904860 DNA anabolism involved in DNA replication involved in S phase involved in mitotic cell cycle|DNA anabolism involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|DNA biosynthetic process involved in DNA replication during S phase involved in mitotic cell cycle|DNA biosynthesis involved in DNA replication during S phase involved in mitotic cell cycle|DNA synthesis involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|DNA biosynthetic process involved in DNA replication involved in S phase involved in mitotic cell cycle|DNA biosynthesis involved in DNA replication involved in S phase involved in mitotic cell cycle|DNA anabolism involved in DNA replication during S phase involved in mitotic cell cycle|DNA formation involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|DNA formation involved in mitotic cell cycle DNA replication|DNA biosynthesis involved in mitotic DNA replication|DNA formation involved in DNA replication involved in S-phase involved in mitotic cell cycle|DNA synthesis involved in DNA replication during S phase involved in mitotic cell cycle|DNA synthesis involved in mitotic cell cycle DNA replication|DNA formation involved in mitotic nuclear cell cycle DNA replication|DNA synthesis involved in DNA replication involved in S-phase involved in mitotic cell cycle|DNA formation involved in DNA replication during S phase involved in mitotic cell cycle|DNA anabolism involved in mitotic cell cycle DNA replication|DNA anabolism involved in mitotic DNA replication|DNA synthesis involved in mitotic nuclear cell cycle DNA replication|DNA anabolism involved in DNA replication involved in S-phase involved in mitotic cell cycle|DNA biosynthetic process involved in mitotic cell cycle DNA replication|DNA anabolism involved in mitotic nuclear cell cycle DNA replication|DNA biosynthesis involved in mitotic cell cycle DNA replication|DNA formation involved in mitotic DNA replication|DNA biosynthetic process involved in DNA replication involved in S-phase involved in mitotic cell cycle|DNA formation involved in DNA replication involved in S phase involved in mitotic cell cycle|DNA biosynthesis involved in DNA replication involved in S-phase involved in mitotic cell cycle|DNA biosynthetic process involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|DNA biosynthesis involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|DNA biosynthetic process involved in mitotic DNA replication|DNA biosynthetic process involved in mitotic nuclear cell cycle DNA replication|DNA synthesis involved in DNA replication involved in S phase involved in mitotic cell cycle|DNA biosynthesis involved in mitotic nuclear cell cycle DNA replication Any DNA biosynthetic process that is involved in mitotic DNA replication. CHEBI:132104 O(3)-(N-acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132104 CHEBI:132105 O(3)-(N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132105 CHEBI:8273 plumbagin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_8273 GO:1904869 regulation of protein localization to Cajal body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904869 regulation of protein localisation in Cajal body|regulation of protein localization in Cajal body|regulation of protein localisation to Cajal body Any process that modulates the frequency, rate or extent of protein localization to Cajal body. GO:1904868 telomerase catalytic core complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904868 telomerase catalytic core complex formation|TERT-TERC complex formation|TERT-TERC complex assembly The aggregation, arrangement and bonding together of a set of components to form a telomerase catalytic core complex. GO:1904867 protein localization to Cajal body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904867 protein localization in Cajal body|protein localisation to Cajal body|protein localisation in Cajal body A process in which a protein is transported to, or maintained in, a location within a Cajal body. CHEBI:132118 S-(2-carboxy-2-methylbut-3-en-2-yl)glutathione biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132118 GO:1904866 ventral tegmental area development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904866 a10a development|ventral tegmental nucleus (tsai) development|VTA development|ventral tegmental area of tsai development|ventral tegmental area (Tsai) development|ventral tegmentum development|area tegmentalis ventralis (Tsai) development|tegmentum ventrale development|ventral tegmental nucleus of tsai development|ventral tegmental nucleus (Rioch) development|ventral brain stem development|ventromedial mesencephalic tegmentum development|area tegmentalis ventralis development The process whose specific outcome is the progression of a ventral tegmental area (VTA) over time, from its formation to the mature structure. GO:1904865 positive regulation of beta-catenin-TCF complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904865 positive regulation of beta-catenin/LEF complex assembly|activation of beta-catenin/lymphoid enhancer binding factor complex formation|upregulation of beta-catenin/LEF complex formation|activation of beta-catenin/LEF complex assembly|upregulation of beta-catenin/T-cell factor complex assembly|up-regulation of beta-catenin-TCF complex formation|up-regulation of beta-catenin/lymphoid enhancer binding factor complex formation|activation of beta-catenin-TCF complex formation|upregulation of beta-catenin-TCF complex assembly|upregulation of beta-catenin/T-cell factor complex formation|up-regulation of beta-catenin/lymphoid enhancer binding factor complex assembly|up-regulation of beta-catenin/LEF complex assembly|up-regulation of beta-catenin/LEF complex formation|activation of beta-catenin/lymphoid enhancer binding factor complex assembly|upregulation of beta-catenin/lymphoid enhancer binding factor complex formation|up regulation of beta-catenin-TCF complex assembly|up-regulation of beta-catenin/T-cell factor complex formation|up regulation of beta-catenin/T-cell factor complex assembly|positive regulation of beta-catenin-TCF complex formation|activation of beta-catenin-TCF complex assembly|positive regulation of beta-catenin/T-cell factor complex assembly|activation of beta-catenin/LEF complex formation|positive regulation of beta-catenin/lymphoid enhancer binding factor complex assembly|up regulation of beta-catenin-TCF complex formation|up regulation of beta-catenin/lymphoid enhancer binding factor complex assembly|upregulation of beta-catenin/LEF complex assembly|activation of beta-catenin/T-cell factor complex formation|activation of beta-catenin/T-cell factor complex assembly|positive regulation of beta-catenin/LEF complex formation|up regulation of beta-catenin/lymphoid enhancer binding factor complex formation|up regulation of beta-catenin/LEF complex formation|positive regulation of beta-catenin/T-cell factor complex formation|positive regulation of beta-catenin/lymphoid enhancer binding factor complex formation|upregulation of beta-catenin-TCF complex formation|up-regulation of beta-catenin/T-cell factor complex assembly|up regulation of beta-catenin/T-cell factor complex formation|up-regulation of beta-catenin-TCF complex assembly|up regulation of beta-catenin/LEF complex assembly|upregulation of beta-catenin/lymphoid enhancer binding factor complex assembly Any process that activates or increases the frequency, rate or extent of beta-catenin-TCF complex assembly. GO:1904864 negative regulation of beta-catenin-TCF complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904864 down regulation of beta-catenin/LEF complex formation|inhibition of beta-catenin/lymphoid enhancer binding factor complex assembly|inhibition of beta-catenin/T-cell factor complex assembly|down regulation of beta-catenin/T-cell factor complex formation|negative regulation of beta-catenin/LEF complex assembly|down-regulation of beta-catenin/LEF complex assembly|inhibition of beta-catenin/LEF complex formation|down regulation of beta-catenin/T-cell factor complex assembly|down regulation of beta-catenin-TCF complex assembly|inhibition of beta-catenin/T-cell factor complex formation|inhibition of beta-catenin/lymphoid enhancer binding factor complex formation|downregulation of beta-catenin/T-cell factor complex assembly|negative regulation of beta-catenin-TCF complex formation|downregulation of beta-catenin-TCF complex assembly|down-regulation of beta-catenin-TCF complex formation|negative regulation of beta-catenin/lymphoid enhancer binding factor complex assembly|down-regulation of beta-catenin/lymphoid enhancer binding factor complex assembly|inhibition of beta-catenin/LEF complex assembly|down regulation of beta-catenin/lymphoid enhancer binding factor complex formation|down-regulation of beta-catenin/LEF complex formation|negative regulation of beta-catenin/LEF complex formation|down-regulation of beta-catenin/T-cell factor complex assembly|negative regulation of beta-catenin/T-cell factor complex assembly|downregulation of beta-catenin-TCF complex formation|downregulation of beta-catenin/lymphoid enhancer binding factor complex formation|down-regulation of beta-catenin-TCF complex assembly|downregulation of beta-catenin/lymphoid enhancer binding factor complex assembly|down-regulation of beta-catenin/T-cell factor complex formation|negative regulation of beta-catenin/T-cell factor complex formation|down regulation of beta-catenin/LEF complex assembly|down regulation of beta-catenin-TCF complex formation|down regulation of beta-catenin/lymphoid enhancer binding factor complex assembly|inhibition of beta-catenin-TCF complex formation|downregulation of beta-catenin/LEF complex assembly|inhibition of beta-catenin-TCF complex assembly|downregulation of beta-catenin/LEF complex formation|down-regulation of beta-catenin/lymphoid enhancer binding factor complex formation|negative regulation of beta-catenin/lymphoid enhancer binding factor complex formation|downregulation of beta-catenin/T-cell factor complex formation Any process that stops, prevents or reduces the frequency, rate or extent of beta-catenin-TCF complex assembly. GO:1904863 regulation of beta-catenin-TCF complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904863 regulation of beta-catenin/T-cell factor complex formation|regulation of beta-catenin/T-cell factor complex assembly|regulation of beta-catenin/lymphoid enhancer binding factor complex formation|regulation of beta-catenin-TCF complex formation|regulation of beta-catenin/LEF complex assembly|regulation of beta-catenin/lymphoid enhancer binding factor complex assembly|regulation of beta-catenin/LEF complex formation Any process that modulates the frequency, rate or extent of beta-catenin-TCF complex assembly. GO:1904862 inhibitory synapse assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904862 inhibitory synapse formation The aggregation, arrangement and bonding together of a set of components to form an inhibitory synapse. GO:1904861 excitatory synapse assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904861 excitatory synapse formation The aggregation, arrangement and bonding together of a set of components to form an excitatory synapse. GO:1904871 positive regulation of protein localization to Cajal body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904871 up-regulation of protein localisation in Cajal body|activation of protein localisation in Cajal body|positive regulation of protein localisation to Cajal body|up regulation of protein localisation to Cajal body|up-regulation of protein localization in Cajal body|activation of protein localization in Cajal body|up regulation of protein localization to Cajal body|positive regulation of protein localisation in Cajal body|upregulation of protein localisation to Cajal body|up regulation of protein localisation in Cajal body|positive regulation of protein localization in Cajal body|up regulation of protein localization in Cajal body|upregulation of protein localization to Cajal body|up-regulation of protein localisation to Cajal body|upregulation of protein localisation in Cajal body|activation of protein localisation to Cajal body|up-regulation of protein localization to Cajal body|upregulation of protein localization in Cajal body|activation of protein localization to Cajal body Any process that activates or increases the frequency, rate or extent of protein localization to Cajal body. GO:1904870 negative regulation of protein localization to Cajal body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904870 down-regulation of protein localization to Cajal body|downregulation of protein localisation to Cajal body|negative regulation of protein localisation in Cajal body|down-regulation of protein localisation in Cajal body|down regulation of protein localisation to Cajal body|inhibition of protein localisation to Cajal body|downregulation of protein localization to Cajal body|negative regulation of protein localization in Cajal body|down-regulation of protein localization in Cajal body|downregulation of protein localisation in Cajal body|down regulation of protein localization to Cajal body|inhibition of protein localization to Cajal body|down regulation of protein localisation in Cajal body|inhibition of protein localisation in Cajal body|downregulation of protein localization in Cajal body|down regulation of protein localization in Cajal body|inhibition of protein localization in Cajal body|negative regulation of protein localisation to Cajal body|down-regulation of protein localisation to Cajal body Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to Cajal body. CHEBI:132115 UDP-N-acetyl-alpha-D-galactosamine 4,6-bissulfate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132115 CHEBI:132114 UDP-N-acetyl-alpha-D-galactosamine 4-sulfate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132114 CHEBI:132117 indolmycenic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132117 CHEBI:132116 2-hydroxyisobutanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132116 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904879 up-regulation of generation of L-type calcium current|positive regulation of generation of L-type calcium current|activation of generation of L-type calcium current|up regulation of generation of L-type calcium current|upregulation of generation of L-type calcium current Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transport via high voltage-gated calcium channel. GO:1904878 negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904878 negative regulation of generation of L-type calcium current|down-regulation of generation of L-type calcium current|downregulation of generation of L-type calcium current|down regulation of generation of L-type calcium current|inhibition of generation of L-type calcium current Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transport via high voltage-gated calcium channel. GO:1904877 positive regulation of DNA ligase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904877 up regulation of DNA ligase activity|activation of DNA ligase activity|up-regulation of DNA ligase activity|upregulation of DNA ligase activity Any process that activates or increases the frequency, rate or extent of DNA ligase activity. GO:1904876 negative regulation of DNA ligase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904876 downregulation of DNA ligase activity|down-regulation of DNA ligase activity|inhibition of DNA ligase activity|down regulation of DNA ligase activity Any process that stops, prevents or reduces the frequency, rate or extent of DNA ligase activity. GO:1904875 regulation of DNA ligase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904875 Any process that modulates the frequency, rate or extent of DNA ligase activity. GO:1904874 positive regulation of telomerase RNA localization to Cajal body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904874 upregulation of telomerase RNA localization to Cajal body|up regulation of telomerase RNA localization to Cajal body|activation of telomerase RNA localization to Cajal body|up-regulation of telomerase RNA localization to Cajal body Any process that activates or increases the frequency, rate or extent of telomerase RNA localization to Cajal body. GO:1904873 negative regulation of telomerase RNA localization to Cajal body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904873 down regulation of telomerase RNA localization to Cajal body|downregulation of telomerase RNA localization to Cajal body|down-regulation of telomerase RNA localization to Cajal body|inhibition of telomerase RNA localization to Cajal body Any process that stops, prevents or reduces the frequency, rate or extent of telomerase RNA localization to Cajal body. GO:1904872 regulation of telomerase RNA localization to Cajal body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904872 Any process that modulates the frequency, rate or extent of telomerase RNA localization to Cajal body. GO:1904882 regulation of telomerase catalytic core complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904882 regulation of telomerase catalytic core complex formation|regulation of TERT-TERC complex assembly|regulation of TERT-TERC complex formation Any process that modulates the frequency, rate or extent of telomerase catalytic core complex assembly. GO:1904881 cellular response to hydrogen sulfide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904881 cellular response to sulfane|cellular response to dihydridosulfur Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen sulfide stimulus. GO:1904880 response to hydrogen sulfide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904880 response to dihydridosulfur|response to sulfane Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen sulfide stimulus. GO:1904889 regulation of excitatory synapse assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904889 regulation of excitatory synapse formation Any process that modulates the frequency, rate or extent of excitatory synapse assembly. GO:1904888 cranial skeletal system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904888 cranial skeleton development|osteocranium development|craniofacial development|cranium development The process whose specific outcome is the progression of a cranial skeletal system over time, from its formation to the mature structure. The cranial skeletal system is the skeletal subdivision of the head, and includes the skull (cranium plus mandible), pharyngeal and/or hyoid apparatus. GO:1904887 Wnt signalosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904887 Wnt signalosome complex formation|LRP5/6 signalosome assembly|Wnt-LRP5/6 signalosome formation|Wnt signalosome formation|Wnt-LRP5/6 signalosome assembly|LRP6 signalosome assembly|Wnt signalosome complex assembly|LRP6 signalosome formation|LRP5/6 signalosome formation The aggregation, arrangement and bonding together of a set of components to form a Wnt signalosome. GO:1904886 beta-catenin destruction complex disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904886 Axin-APC-beta-catenin-GSK3B complex disassembly|BDC disassembly|beta-catenin degradation complex disassembly|23S APC complex disassembly|APC-Axin-1-beta-catenin complex disassembly|dissociation of beta-catenin degradation complex The disaggregation of a beta-catenin destruction complex into its constituent components. GO:1904885 beta-catenin destruction complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904885 23S APC complex assembly|Axin-APC-beta-catenin-GSK3B complex formation|BDC formation|beta-catenin degradation complex formation|23S APC complex formation|beta-catenin degradation complex assembly|destruction complex formation|BDC assembly|Axin-APC-beta-catenin-GSK3B complex assembly|APC-Axin-1-beta-catenin complex formation|APC-Axin-1-beta-catenin complex assembly|beta-catenin destruction complex formation The aggregation, arrangement and bonding together of a set of components to form a beta-catenin destruction complex. GO:1904884 positive regulation of telomerase catalytic core complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904884 up-regulation of telomerase catalytic core complex formation|activation of TERT-TERC complex assembly|up-regulation of TERT-TERC complex formation|up regulation of telomerase catalytic core complex assembly|positive regulation of TERT-TERC complex assembly|upregulation of telomerase catalytic core complex formation|up regulation of TERT-TERC complex assembly|upregulation of TERT-TERC complex formation|upregulation of telomerase catalytic core complex assembly|up regulation of telomerase catalytic core complex formation|upregulation of TERT-TERC complex assembly|positive regulation of telomerase catalytic core complex formation|activation of telomerase catalytic core complex formation|up regulation of TERT-TERC complex formation|up-regulation of telomerase catalytic core complex assembly|positive regulation of TERT-TERC complex formation|activation of telomerase catalytic core complex assembly|up-regulation of TERT-TERC complex assembly|activation of TERT-TERC complex formation Any process that activates or increases the frequency, rate or extent of telomerase catalytic core complex assembly. GO:1904883 negative regulation of telomerase catalytic core complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904883 down-regulation of telomerase catalytic core complex assembly|inhibition of telomerase catalytic core complex formation|negative regulation of TERT-TERC complex assembly|down-regulation of TERT-TERC complex assembly|downregulation of telomerase catalytic core complex assembly|inhibition of TERT-TERC complex formation|down regulation of telomerase catalytic core complex formation|down regulation of telomerase catalytic core complex assembly|downregulation of TERT-TERC complex assembly|inhibition of telomerase catalytic core complex assembly|downregulation of telomerase catalytic core complex formation|down regulation of TERT-TERC complex formation|down regulation of TERT-TERC complex assembly|downregulation of TERT-TERC complex formation|down-regulation of telomerase catalytic core complex formation|negative regulation of telomerase catalytic core complex formation|inhibition of TERT-TERC complex assembly|down-regulation of TERT-TERC complex formation|negative regulation of TERT-TERC complex formation Any process that stops, prevents or reduces the frequency, rate or extent of telomerase catalytic core complex assembly. GO:1904893 negative regulation of receptor signaling pathway via STAT biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904893 down-regulation of STAT cascade|negative regulation of kinase activated-STAT cascade|down-regulation of kinase activated-STAT cascade|down regulation of STAT signalling pathway|down regulation of kinase-STAT cascade|downregulation of STAT signalling pathway|downregulation of kinase-STAT cascade|downregulation of STAT cascade|inhibition of kinase activated-STAT cascade|down regulation of STAT cascade|inhibition of STAT cascade|down-regulation of STAT signalling pathway|negative regulation of STAT signalling pathway|down-regulation of kinase-STAT cascade|negative regulation of kinase-STAT cascade|down regulation of kinase activated-STAT cascade|inhibition of STAT signalling pathway|inhibition of kinase-STAT cascade|downregulation of kinase activated-STAT cascade Any process that stops, prevents or reduces the frequency, rate or extent of receptor signaling via STAT. GO:1904892 regulation of receptor signaling pathway via STAT biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904892 regulation of STAT signalling pathway|regulation of kinase-STAT cascade|regulation of kinase activated-STAT cascade Any process that modulates the frequency, rate or extent of receptor signaling via STAT. GO:1904891 positive regulation of excitatory synapse assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904891 up regulation of excitatory synapse assembly|positive regulation of excitatory synapse formation|activation of excitatory synapse assembly|up regulation of excitatory synapse formation|upregulation of excitatory synapse formation|up-regulation of excitatory synapse assembly|upregulation of excitatory synapse assembly|up-regulation of excitatory synapse formation|activation of excitatory synapse formation Any process that activates or increases the frequency, rate or extent of excitatory synapse assembly. GO:1904890 negative regulation of excitatory synapse assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904890 down regulation of excitatory synapse assembly|downregulation of excitatory synapse assembly|negative regulation of excitatory synapse formation|down-regulation of excitatory synapse formation|downregulation of excitatory synapse formation|down-regulation of excitatory synapse assembly|down regulation of excitatory synapse formation|inhibition of excitatory synapse formation|inhibition of excitatory synapse assembly Any process that stops, prevents or reduces the frequency, rate or extent of excitatory synapse assembly. GO:1904899 positive regulation of hepatic stellate cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904899 positive regulation of perisinusoidal cell proliferation|positive regulation of hepatic perisinusoidal cell proliferation|up regulation of hepatic stellate cell proliferation|activation of hepatic stellate cell proliferation|positive regulation of Ito cell proliferation|up regulation of Ito cell proliferation|up-regulation of perisinusoidal cell proliferation|up-regulation of hepatic perisinusoidal cell proliferation|up-regulation of hepatic stellate cell proliferation|upregulation of Ito cell proliferation|upregulation of perisinusoidal cell proliferation|upregulation of hepatic perisinusoidal cell proliferation|upregulation of hepatic stellate cell proliferation|activation of Ito cell proliferation|up-regulation of Ito cell proliferation|up regulation of perisinusoidal cell proliferation|up regulation of hepatic perisinusoidal cell proliferation|activation of hepatic perisinusoidal cell proliferation|activation of perisinusoidal cell proliferation Any process that activates or increases the frequency, rate or extent of hepatic stellate cell proliferation. GO:1904898 negative regulation of hepatic stellate cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904898 negative regulation of Ito cell proliferation|down-regulation of Ito cell proliferation|down-regulation of hepatic perisinusoidal cell proliferation|negative regulation of hepatic perisinusoidal cell proliferation|down-regulation of perisinusoidal cell proliferation|negative regulation of perisinusoidal cell proliferation|down-regulation of hepatic stellate cell proliferation|downregulation of Ito cell proliferation|inhibition of hepatic perisinusoidal cell proliferation|inhibition of perisinusoidal cell proliferation|inhibition of hepatic stellate cell proliferation|down regulation of Ito cell proliferation|inhibition of Ito cell proliferation|down regulation of perisinusoidal cell proliferation|down regulation of hepatic perisinusoidal cell proliferation|down regulation of hepatic stellate cell proliferation|downregulation of perisinusoidal cell proliferation|downregulation of hepatic perisinusoidal cell proliferation|downregulation of hepatic stellate cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell proliferation. GO:1904897 regulation of hepatic stellate cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904897 regulation of Ito cell proliferation|regulation of hepatic perisinusoidal cell proliferation|regulation of perisinusoidal cell proliferation Any process that modulates the frequency, rate or extent of hepatic stellate cell proliferation. GO:1904896 ESCRT complex disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904896 endosomal sorting complex required for transport disassembly The disaggregation of an ESCRT complex into its constituent components. GO:1904895 ESCRT complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904895 endosomal sorting complex required for transport formation|ESCRT complex formation|endosomal sorting complex required for transport assembly The aggregation, arrangement and bonding together of a set of components to form an ESCRT complex. GO:1904894 positive regulation of receptor signaling pathway via STAT biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904894 positive regulation of kinase activated-STAT cascade|upregulation of STAT signalling pathway|upregulation of kinase-STAT cascade|up regulation of STAT cascade|up-regulation of kinase activated-STAT cascade|up regulation of STAT signalling pathway|activation of STAT signalling pathway|up regulation of kinase-STAT cascade|positive regulation of STAT signalling pathway|activation of kinase-STAT cascade|positive regulation of kinase-STAT cascade|upregulation of STAT cascade|upregulation of kinase activated-STAT cascade|up-regulation of STAT signalling pathway|up-regulation of kinase-STAT cascade|up-regulation of STAT cascade|activation of STAT cascade|up regulation of kinase activated-STAT cascade|activation of kinase activated-STAT cascade Any process that activates or increases the frequency, rate or extent of receptor signaling pathway via STAT. CHEBI:8298 poly[(R)-3-hydroxybutanoate] biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_8298 CHEBI:64543 fonsecin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64543 CHEBI:64542 naphtho-gamma-pyrone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64542 CHEBI:64548 pyrazinoquinazoline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64548 CHEBI:88514 butyl formate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88514 CHEBI:64547 imidazoindole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64547 CHEBI:64546 fumiquinazoline A biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64546 CHEBI:64545 fumiquinazoline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64545 CHEBI:64549 lysophosphatidylcholine 18:2 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64549 CHEBI:64551 fumiquinazoline C biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64551 CHEBI:64550 fumiquinazoline F biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64550 CHEBI:64555 trans-p-coumaryl alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64555 CHEBI:64554 tryptophan zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64554 CHEBI:64553 tatiopterin(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64553 CHEBI:64552 2-hydroxybutyrate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64552 CHEBI:64558 methionine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64558 CHEBI:64557 trans-sinapyl alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64557 CHEBI:64561 lysophosphatidylcholine 18:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64561 CHEBI:64560 lysophosphatidylcholine 16:1 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64560 CHEBI:64566 lysophosphatidylcholine 18:1 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64566 CHEBI:64565 lysophosphatidylcholine 18:3 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64565 CHEBI:64563 lysophosphatidylcholine 16:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64563 CHEBI:132188 methionine sulfone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132188 CHEBI:64569 lysophosphatidylethanolamine 20:4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64569 CHEBI:64568 lysophosphatidylcholine 20:4 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64568 CHEBI:64567 lysophosphatidylcholine 22:6 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64567 CHEBI:132183 (3S)-hydroxyadipyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132183 CHEBI:64573 1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64573 CHEBI:64572 1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64572 CHEBI:64571 NMDA receptor agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64571 CHEBI:64570 EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64570 CHEBI:64577 flour treatment agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64577 CHEBI:64576 lysophosphatidylethanolamine 18:0 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64576 CHEBI:64575 lysophosphatidylethanolamine 18:1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64575 CHEBI:64574 lysophosphatidylethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64574 CHEBI:132198 pentahydroxyanthraquinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132198 CHEBI:88528 hexanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88528 CHEBI:64584 uremic toxin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64584 CHEBI:64583 sphingomyelin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64583 CHEBI:64588 glycine transporter 1 inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64588 CHEBI:156132 L-thialysinium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_156132 CHEBI:64589 glycine receptor agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64589 GO:1904809 regulation of dense core granule transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904809 regulation of dense core vesicle transport Any process that modulates the frequency, rate or extent of dense core granule transport. GO:1904808 positive regulation of protein oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904808 positive regulation of protein amino acid oxidation|upregulation of protein oxidation|up regulation of protein amino acid oxidation|up regulation of protein oxidation|activation of protein oxidation|upregulation of protein amino acid oxidation|activation of protein amino acid oxidation|up-regulation of protein amino acid oxidation|up-regulation of protein oxidation Any process that activates or increases the frequency, rate or extent of protein oxidation. GO:1904807 negative regulation of protein oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904807 down regulation of protein oxidation|downregulation of protein amino acid oxidation|downregulation of protein oxidation|down regulation of protein amino acid oxidation|inhibition of protein amino acid oxidation|down-regulation of protein oxidation|inhibition of protein oxidation|down-regulation of protein amino acid oxidation|negative regulation of protein amino acid oxidation Any process that stops, prevents or reduces the frequency, rate or extent of protein oxidation. CHEBI:64591 lysophosphatidylcholine O-18:1 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64591 GO:1904806 regulation of protein oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904806 regulation of protein amino acid oxidation Any process that modulates the frequency, rate or extent of protein oxidation. GO:1904805 cellular response to latrunculin A biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904805 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a latrunculin A stimulus. CHEBI:64590 monoalkyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64590 GO:1904804 response to latrunculin A biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904804 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a latrunculin A stimulus. GO:1904803 regulation of translation involved in cellular response to UV biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904803 regulation of translation involved in cellular response to ultraviolet radiation stimulus|regulation of protein anabolism involved in cellular response to UV|regulation of translation involved in cellular response to UV radiation stimulus|regulation of protein synthesis involved in cellular response to UV|regulation of protein formation involved in cellular response to UV|regulation of protein biosynthesis involved in cellular response to UV|regulation of translation involved in cellular response to ultraviolet light stimulus|regulation of translation involved in cellular response to UV light stimulus Any regulation of translation that is involved in cellular response to UV. GO:1904802 RITS complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904802 RITS complex formation The aggregation, arrangement and bonding together of a set of components to form a RITS complex. CHEBI:64595 1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64595 GO:1904801 positive regulation of neuron remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904801 activation of axon pruning|up regulation of neuron remodeling|upregulation of neuronal remodeling|activation of neuron remodeling|positive regulation of axon pruning|up regulation of axon pruning|up regulation of neuronal remodeling|up-regulation of neuron remodeling|activation of neuronal remodeling|positive regulation of neuronal remodeling|upregulation of axon pruning|upregulation of neuron remodeling|up-regulation of neuronal remodeling|up-regulation of axon pruning Any process that activates or increases the frequency, rate or extent of neuron remodeling. GO:1904800 negative regulation of neuron remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904800 downregulation of neuron remodeling|negative regulation of axon pruning|down-regulation of axon pruning|down regulation of neuronal remodeling|down-regulation of neuron remodeling|downregulation of neuronal remodeling|downregulation of axon pruning|inhibition of neuron remodeling|down regulation of axon pruning|negative regulation of neuronal remodeling|down-regulation of neuronal remodeling|inhibition of axon pruning|inhibition of neuronal remodeling|down regulation of neuron remodeling Any process that stops, prevents or reduces the frequency, rate or extent of neuron remodeling. CHEBI:64593 lysophosphatidylcholine O-16:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64593 CHEBI:64599 4-amino-3-isothiazolidinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64599 CHEBI:64598 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64598 CHEBI:64596 1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64596 CHEBI:132177 2-hydroxy-3-methyl-2-butenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132177 CHEBI:132174 beta-D-glucosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl undecaprenyl diphosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132174 GO:1904819 parietal peritoneum development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904819 peritoneal cavity lining development The process whose specific outcome is the progression of a parietal peritoneum over time, from its formation to the mature structure. GO:1904818 visceral peritoneum development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904818 The process whose specific outcome is the progression of a visceral peritoneum over time, from its formation to the mature structure. GO:1904817 serous membrane development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904817 serosa development|wall of serous sac development|tunica serosa development The process whose specific outcome is the progression of a serous membrane over time, from its formation to the mature structure. GO:1904816 positive regulation of protein localization to chromosome, telomeric region biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904816 positive regulation of protein localization to telomere|up regulation of protein localization to chromosome, telomeric region|up regulation of protein localization to telomere|upregulation of protein localisation to chromosome, telomeric region|upregulation of protein localization to chromosome, telomeric region|upregulation of protein localization to telomere|activation of protein localisation to chromosome, telomeric region|up-regulation of protein localisation to chromosome, telomeric region|up-regulation of protein localization to chromosome, telomeric region|activation of protein localization to chromosome, telomeric region|up-regulation of protein localization to telomere|activation of protein localization to telomere|positive regulation of protein localisation to chromosome, telomeric region|up regulation of protein localisation to chromosome, telomeric region Any process that activates or increases the frequency, rate or extent of protein localization to chromosome, telomeric region. GO:1904815 negative regulation of protein localization to chromosome, telomeric region biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904815 down regulation of protein localisation to chromosome, telomeric region|inhibition of protein localisation to chromosome, telomeric region|downregulation of protein localization to chromosome, telomeric region|downregulation of protein localization to telomere|down regulation of protein localization to chromosome, telomeric region|down regulation of protein localization to telomere|inhibition of protein localization to chromosome, telomeric region|inhibition of protein localization to telomere|negative regulation of protein localisation to chromosome, telomeric region|down-regulation of protein localisation to chromosome, telomeric region|down-regulation of protein localization to chromosome, telomeric region|down-regulation of protein localization to telomere|negative regulation of protein localization to telomere|downregulation of protein localisation to chromosome, telomeric region Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to chromosome, telomeric region. GO:1904814 regulation of protein localization to chromosome, telomeric region biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904814 regulation of protein localisation to chromosome, telomeric region|regulation of protein localization to telomere Any process that modulates the frequency, rate or extent of protein localization to chromosome, telomeric region. GO:1904813 ficolin-1-rich granule lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1904813 membrane-enclosed lumen of ficolin-1 rich granule|membrane-enclosed lumen of ficolin granule|ficolin-1-rich granule membrane-enclosed lumen|membrane-enclosed lumen of ficolin-1-rich granule Any membrane-enclosed lumen that is part of a ficolin-1-rich granule. GO:1904812 rRNA acetylation involved in maturation of SSU-rRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904812 rRNA acetylation involved in SSU-rRNA maturation|rRNA acetylation involved in processing of 20S pre-rRNA Any rRNA acetylation that is involved in maturation of SSU-rRNA. GO:1904811 positive regulation of dense core granule transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904811 upregulation of dense core vesicle transport|upregulation of dense core granule transport|up-regulation of dense core vesicle transport|up-regulation of dense core granule transport|activation of dense core vesicle transport|activation of dense core granule transport|positive regulation of dense core vesicle transport|up regulation of dense core vesicle transport|up regulation of dense core granule transport Any process that activates or increases the frequency, rate or extent of dense core granule transport. GO:1904810 negative regulation of dense core granule transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904810 downregulation of dense core granule transport|down regulation of dense core vesicle transport|down regulation of dense core granule transport|inhibition of dense core vesicle transport|inhibition of dense core granule transport|down-regulation of dense core vesicle transport|negative regulation of dense core vesicle transport|down-regulation of dense core granule transport|downregulation of dense core vesicle transport Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule transport. CHEBI:132149 prostaglandin D3(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132149 CHEBI:132142 1,4-naphthoquinones biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132142 GO:1904829 regulation of aortic smooth muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904829 Any process that modulates the frequency, rate or extent of aortic smooth muscle cell differentiation. GO:1904828 positive regulation of hydrogen sulfide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904828 up regulation of hydrogen sulfide biosynthesis|up regulation of hydrogen sulfide biosynthetic process|activation of hydrogen sulfide biosynthesis|activation of hydrogen sulfide biosynthetic process|up-regulation of hydrogen sulfide formation|activation of hydrogen sulfide formation|positive regulation of hydrogen sulfide biosynthesis|positive regulation of hydrogen sulfide anabolism|positive regulation of hydrogen sulphide biosynthetic process|positive regulation of hydrogen sulphide biosynthesis|up regulation of hydrogen sulfide anabolism|up regulation of hydrogen sulphide biosynthesis|positive regulation of hydrogen sulfide synthesis|up regulation of hydrogen sulphide biosynthetic process|up regulation of hydrogen sulfide synthesis|positive regulation of hydrogen sulfide formation|up-regulation of hydrogen sulfide biosynthesis|up-regulation of hydrogen sulfide biosynthetic process|up regulation of hydrogen sulfide formation|upregulation of hydrogen sulfide anabolism|upregulation of hydrogen sulphide biosynthesis|upregulation of hydrogen sulphide biosynthetic process|upregulation of hydrogen sulfide biosynthetic process|upregulation of hydrogen sulfide biosynthesis|upregulation of hydrogen sulfide synthesis|upregulation of hydrogen sulfide formation|up-regulation of hydrogen sulfide anabolism|activation of hydrogen sulfide anabolism|activation of hydrogen sulphide biosynthesis|up-regulation of hydrogen sulphide biosynthetic process|up-regulation of hydrogen sulphide biosynthesis|activation of hydrogen sulphide biosynthetic process|up-regulation of hydrogen sulfide synthesis|activation of hydrogen sulfide synthesis Any process that activates or increases the frequency, rate or extent of hydrogen sulfide biosynthetic process. GO:1904827 negative regulation of hydrogen sulfide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904827 negative regulation of hydrogen sulfide anabolism|down-regulation of hydrogen sulfide anabolism|negative regulation of hydrogen sulphide biosynthesis|down-regulation of hydrogen sulphide biosynthetic process|down-regulation of hydrogen sulphide biosynthesis|negative regulation of hydrogen sulphide biosynthetic process|negative regulation of hydrogen sulfide biosynthesis|down-regulation of hydrogen sulfide biosynthetic process|down-regulation of hydrogen sulfide biosynthesis|negative regulation of hydrogen sulfide synthesis|down-regulation of hydrogen sulfide synthesis|negative regulation of hydrogen sulfide formation|down-regulation of hydrogen sulfide formation|downregulation of hydrogen sulfide anabolism|downregulation of hydrogen sulphide biosynthesis|inhibition of hydrogen sulfide biosynthesis|inhibition of hydrogen sulfide biosynthetic process|downregulation of hydrogen sulphide biosynthetic process|down regulation of hydrogen sulfide anabolism|downregulation of hydrogen sulfide synthesis|down regulation of hydrogen sulphide biosynthesis|down regulation of hydrogen sulphide biosynthetic process|inhibition of hydrogen sulfide anabolism|downregulation of hydrogen sulfide formation|inhibition of hydrogen sulphide biosynthesis|down regulation of hydrogen sulfide synthesis|inhibition of hydrogen sulphide biosynthetic process|inhibition of hydrogen sulfide synthesis|down regulation of hydrogen sulfide formation|inhibition of hydrogen sulfide formation|down regulation of hydrogen sulfide biosynthetic process|down regulation of hydrogen sulfide biosynthesis|downregulation of hydrogen sulfide biosynthesis|downregulation of hydrogen sulfide biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen sulfide biosynthetic process. GO:1904826 regulation of hydrogen sulfide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904826 regulation of hydrogen sulfide anabolism|regulation of hydrogen sulphide biosynthesis|regulation of hydrogen sulphide biosynthetic process|regulation of hydrogen sulfide synthesis|regulation of hydrogen sulfide formation|regulation of hydrogen sulfide biosynthesis Any process that modulates the frequency, rate or extent of hydrogen sulfide biosynthetic process. GO:1904825 protein localization to microtubule plus-end biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904825 protein localisation to microtubule plus-end A process in which a protein is transported to, or maintained in, a location at a microtubule plus-end. GO:1904824 anaphase-promoting complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904824 cyclosome assembly|anaphase-promoting complex formation|APC assembly|cyclosome formation|anaphase promoting complex assembly|anaphase promoting complex formation The aggregation, arrangement and bonding together of a set of components to form an anaphase-promoting complex. GO:1904823 purine nucleobase transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904823 The process in which a purine nucleobase is transported across a membrane. GO:1904822 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1904822 GO:1904821 chloroplast disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904821 chloroplast degradation The disaggregation of a chloroplast into its constituent components. GO:1904820 peritoneum development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904820 peritonaeum development The process whose specific outcome is the progression of a peritoneum over time, from its formation to the mature structure. CHEBI:146781 mature microcin B18 zwitterion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_146781 CHEBI:132155 hydroxynaphthoquinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132155 CHEBI:132154 N-acetyl-beta-D-glucosaminyl-(1->4)-[hyaluronate] biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132154 CHEBI:132157 hydroxy-1,4-naphthoquinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132157 CHEBI:132151 beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-D-GlcpNAc(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132151 CHEBI:132153 hyaluronate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132153 CHEBI:15529 lactoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15529 DDANAT:0000083 Dictyostelium discoideum single cell organism biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000083 D. discoideum single cell organism Cell that is an individual member of the species Dictyostelium discoideum. CHEBI:15525 palmitoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15525 DDANAT:0000086 prespore region biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000086 psp region Region mostly composed of prespore cells. In addition to prespore cells, the prespore region contains anterior-like cells (ALC) that express ecmA and/or ecmB. The prespore region occupies about three quarters of the organism. CHEBI:15528 itaconyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15528 CHEBI:15527 icosanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15527 CHEBI:15522 formyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15522 CHEBI:15521 lauroyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15521 CHEBI:15524 glutaryl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15524 CHEBI:15523 cis-geranoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15523 CHEBI:15520 cyclohexa-1,5-diene-1-carbonyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15520 DDANAT:0000066 inner basal disc of the late culminant biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000066 Central portion of the basal disc of the late culminant. Composed of stalk cells. CHEBI:15519 choloyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15519 DDANAT:0000065 basal disc of the late culminant biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000065 Conical-shaped structure of the late culminant that anchors the stalk to the substratum. Composed of anterior-like cells. CHEBI:15518 caffeoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15518 DDANAT:0000068 stalk of the fruiting body biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000068 sorophore of the fruiting body Tubular structure of the fruiting body that consists of cellulose-covered cells stacked on top of each other and surrounded by an acellular stalk tube composed of cellulose and glycoprotein. The stalk of the mature fruiting body is usually 5-15 microns in diameter and between 1.5 to 3 cm in height. DDANAT:0000073 basal disc of the fruiting body biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000073 Conical-shaped structure of the fruiting body that anchors the stalk to the substratum, around 150 to 400 microns in diameter. Composed of anterior-like cells. CHEBI:15515 benzoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15515 CHEBI:15514 arachidonoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15514 CHEBI:15517 butyryl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15517 CHEBI:15516 biotinyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15516 DDANAT:0000074 inner basal disc of the fruiting body biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000074 Central portion of the basal disc of the fruiting body composed of stalk cells. CHEBI:15511 trans-feruloyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15511 CHEBI:15510 5-hydroxy-2-furoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15510 CHEBI:15513 acryloyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15513 DDANAT:0000070 sorus of the fruiting body biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000070 spore head of the fruiting body Structure of the fruiting body supported by the stalk and that contains the spores. The sorus is 125-300 microns in diameter, lemon-shaped, and grayish white to pale yellow in color. CHEBI:15512 L-3-aminobutanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15512 DDANAT:0000059 stalk of the late culminant biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000059 sorophore of the late culminant Tubular structure of the late culminant that consists of cellulose-covered cells stacked on top of each other and surrounded by an acellular stalk tube composed of cellulose and glycoprotein. DDANAT:0000054 prespore region of the mid culminant biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000054 psp region of the mid culminant Region of the mid culminant mostly composed of prespore cells. In addition to prespore cells, the prespore region contains anterior-like cells (ALC) that express ecmA and/or ecmB. The prespore region occupies about three quarters of the organism. DDANAT:0000057 basal disc of the mid culminant biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000057 Region located of the mid culminant located closest to the substratum and composed of pst cells (rearguard cells). CHEBI:15548 15-dehydro-prostaglandin E1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15548 DDANAT:0000061 sorus of the late culminant biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000061 spore head of the late culminant Ovoid structure of the late culminant supported by the stalk and that contains the spores. CHEBI:15547 15-dehydro-prostaglandin E2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15547 CHEBI:15544 prostaglandin E1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15544 CHEBI:15543 vinylacetyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15543 CHEBI:15546 prostaglandin C1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15546 CHEBI:15545 prostaglandin A1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15545 CHEBI:15540 sinapoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15540 CHEBI:15542 thiophene-2-carbonyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15542 CHEBI:15541 stearoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15541 DDANAT:0000048 prestalk region of the mid culminant biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000048 pst region of the mid culminant The prestalk region of the mid culminant is located at the most apical part of the organism. It consists of about one quarter of the cells. DDANAT:0000049 prestalk A region of the mid culminant biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000049 pstA region of the mid culminant Anterior-most region of the prestalk zone of the mid culminant characterized by high expression of the ecmA gene directed by the proximal part of its promoter (ecmA promoter). DDANAT:0000045 basal region of the early culminant biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000045 base of the early culminant Region of the early culminant located at the closest to the substratum composed of pstB cells that originated from rearguard cells. DDANAT:0000051 prestalk AB core region of the mid culminant biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000051 prestalk AB region of the mid culminant|pstAB region of the mid culminant Cone-shaped area of the prestalk zone of the mid culminant that occupies a core among the pstA region. Cells of the pstAB region express both the ecmA and ecmB genes. CHEBI:15537 phenylacetyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15537 CHEBI:15536 pentanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15536 CHEBI:15539 propionyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15539 DDANAT:0000052 stalk of the mid culminant biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000052 sorophore of the mid culminant Tubular structure of the mid culminant that consists of cellulose-covered cells stacked on top of each other and surrounded by an acellular stalk tube composed of cellulose and glycoprotein. CHEBI:15538 phytanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15538 CHEBI:15533 octanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15533 CHEBI:15532 myristoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15532 CHEBI:15535 oxalyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15535 CHEBI:15534 oleoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15534 CHEBI:15531 malonyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15531 CHEBI:15530 linoleoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15530 dc:title title biolink:OntologyClass go-plus http://purl.org/dc/elements/1.1/title DDANAT:0000037 prestalk region of the early culminant biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000037 pst region of the early culminant The prestalk region of the early culminant is located at the most apical part of the organism. It consists of about one quarter of the cells. DDANAT:0000038 prestalk A region of the early culminant biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000038 pstA region of the early culminant Anterior-most region of the prestalk zone of the early culminant characterized by high expression of the ecmA gene directed by the proximal part of its promoter (ecmA promoter). DDANAT:0000033 prespore region of the migratory slug biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000033 psp region of the migratory slug Region of the migratory slug composed mostly of prespore cells. In addition to prespore cells, the prespore region contains anterior-like cells (ALC) that express ecmA and/or ecmB. The prespore region occupies about three quarters of the organism. DDANAT:0000032 prestalk AB core region of the migratory slug biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000032 prestalk AB region of the migratory slug|pstAB region of the migratory slug Cone-shaped area of the prestalk zone of the migratory slug that occupies a core among the pstA region. Cells of the pstAB region express both the ecmA and ecmB genes. DDANAT:0000040 prestalk AB core region of the early culminant biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000040 prestalk AB region of the early culminant|pstAB region of the early culminant Cone-shaped area of the prestalk zone of the early culminant that occupies a core among the pstA region. Cells of the pstAB region express both the ecmA and ecmB genes. CHEBI:64504 phosphatidylcholine 36:5 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64504 CHEBI:64503 nonadec-1-ene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64503 CHEBI:64502 1-heptadecene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64502 DDANAT:0000041 prespore region of the early culminant biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000041 psp region of the early culminant Region of the early culminant mostly composed of prespore cells. In addition to prespore cells, the prespore region contains anterior-like cells (ALC) that express ecmA and/or ecmB. The prespore region occupies about three quarters of the organism. CHEBI:64508 17-methylnonadec-1-ene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64508 CHEBI:64507 18-methylnonadec-1-ene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64507 CHEBI:64506 (Z)-nonadeca-1,14-diene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64506 CHEBI:64509 oxapenam biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64509 DDANAT:0000025 basal region of the standing slug biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000025 base of the standing slug Region of the standing slug in contact with the substratum and composed of prestalk B cells. DDANAT:0000028 prestalk region of the migratory slug biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000028 pst region of the migratory slug|anterior region of the migratory slug The prestalk region of the migratory slug is located at the anterior of the organism. It consists of about one quarter of the cells. DDANAT:0000021 prestalk A region of the standing slug biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000021 pstA region of the standing slug Most apical region of the prestalk zone of the standing slug characterized by high expression of the ecmA gene directed by the proximal part of its promoter (ecmA promoter). CHEBI:64510 carbapenam biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64510 DDANAT:0000024 prespore region of the standing slug biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000024 psp region of the standing slug Region of the standing slug mostly composed of prespore cells. In addition to prespore cells, the prespore region contains anterior-like cells (ALC) that express ecmA and/or ecmB. The prespore region occupies about three quarters of the organism. DDANAT:0000023 prestalk AB core region of the standing slug biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000023 pstAB region|prestalk AB region of the standing slug Cone-shaped area of the prestalk zone of the standing slug that occupies a core among the pstA region. Cells of the pstAB region express both the ecmA and ecmB genes. CHEBI:64515 pyranoxanthene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64515 CHEBI:64514 sarcinapterin(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64514 DDANAT:0000030 prestalk A region of the migratory slug biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000030 pstAO region of the migratory slug|pstA region of the migratory slug|prestalk AO region of the migratory slug Anterior-most region of the prestalk zone of the migratory slug and characterized by high expression of the ecmA gene directed by the proximal part of its promoter (ecmA promoter). CHEBI:64512 emericellin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64512 CHEBI:64519 phosphatidylcholine 38:6 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64519 CHEBI:64518 cordyol C biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64518 CHEBI:64517 phosphatidylcholine 34:1 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64517 CHEBI:64516 phosphatidylcholine 34:2 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64516 DDANAT:0000019 prestalk region of the standing slug biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000019 pst region of the standing slug Elongated protrusion of the standing slug located on top of the cell mass that contains pstA cells flanked by pstO cells (expressing ecmA from the proximal and the distal part of its promoter, respectively). DDANAT:0000017 prespore region of the tipped mound biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000017 psp region of the tipped mound Region of the tipped mound mostly composed of prespore cells. In addition to prespore cells, the prespore region contains anterior-like cells (ALC) that express ecmA and/or ecmB. DDANAT:0000016 prestalk region of the tipped mound biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000016 apical tip of the tipped mound|pst region of the tipped mound Elongated protusion of the tipped mound located on top of the cell mass that contains pstA cells flanked by pstO cells (expressing ecmA from the proximal and the distal part of its promoter, respectively). DDANAT:0000011 late culminant biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000011 pseudoplasmodium|culminant Structure in which stalk tube formation has progressed down to the basal disc. The sorogen ascents up the stalk to it apical position during this stage. Terminal differentiation occurs at this stage: death of the stalk cells and encapsulation of the spores. CHEBI:15508 gamma-linolenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15508 CHEBI:64522 averantin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64522 DDANAT:0000010 mid culminant biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000010 pseudoplasmodium|culminant Structure in which stalk tube formation has progressed down the prespore zone. Basal disc formation begins at this stage, with the migration of pstA and pstB cells to the lower part of the culminant to form the basal disc. CHEBI:15507 beta-alanyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15507 DDANAT:0000013 stream biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000013 pseudoplasmodial stream Macroscopic appearance of groups of chemotactic cells orienting themselves in a head to tail fashion as they are migrating in the direction of the chemotactic stimulus to form aggregates. CHEBI:64520 phosphatidylcholine 36:4 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64520 DDANAT:0000012 fruiting body biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000012 sorocarp Dicty asexual organism which is terminally differentiated and consists of a long stalk on top of which sits the sorus that contains spores. The mature fruiting body measures between 1.5 to 3 mm in height. CHEBI:15509 4-(2-carboxyphenyl)-4-oxobutanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15509 CHEBI:64526 phosphatidylcholine 38:4 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64526 CHEBI:15504 pimeloyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15504 CHEBI:15503 2,3-didehydropimeloyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15503 CHEBI:64525 phosphatidylcholine 38:5 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64525 CHEBI:64523 phosphatidylcholine 36:3 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64523 CHEBI:15505 6-hydroxycyclohex-1-ene-1-carbonyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15505 CHEBI:15500 4-hydroxybenzoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15500 CHEBI:15502 5-hydroxythiophene-2-carbonyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15502 CHEBI:15501 5-hydroxypentanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15501 DDANAT:0000008 migratory slug biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000008 pseudoplasmodium When the conditions are not optimal for the completion of development, the standing slug bends from a vertical position to a horizontal position, producing a migratory that slug has the ability to migrate towards more favorable environmental conditions. The slug is cylindrical in shape with a rounded, tapering region at its anterior end that is raised with respect to the substratum. It usually measures between 0.8 to 1.2 mm in length with a diameter of 0.15 to 0.25 mm. Slugs sense and respond to light, temperature and acidity, and do not enter culmination until the conditions are optimal. The slug can move at a speed of 0.5 to 2 mm per hour. A trail of slime is deposited on the surface during migration. DDANAT:0000007 standing slug biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000007 finger|pseudoplasmodium|first finger Cylindrical structure that is formed by elongation of the mound under the control of the tip. The elongating tip is called the first finger. DDANAT:0000009 early culminant biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000009 mexican hat|culminant|pseudoplasmodium Structure formed after the arrest of slug migration formed when cells of the posterior region of the slug move under the tip. Stalk tube formation is initiated at this stage. DDANAT:0000004 loose aggregate biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000004 loose mound First adherent mass of cells observed during development, relatively flat with indistinct borders. DDANAT:0000003 aggregation territory biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000003 Area covered by a group of chemotactic cells converging toward the same aggregation center. Can reach a diameter of up to 1 cm. DDANAT:0000006 tipped mound biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000006 tipped aggregate|pseudoplasmodium Hemispherical structure composed of post-aggregative cells that are undergoing differentiation and that have formed a tip. DDANAT:0000005 mound biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000005 tight mound|pseudoplasmodium|tight aggregate Hemispherical structure composed of post-aggregative cells that are undergoing differentiation. CHEBI:64532 dihydroxytoluene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64532 CHEBI:64531 fumitremorgin B biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64531 CHEBI:64530 brevianamide F biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64530 CHEBI:64535 pseurotin A biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64535 CHEBI:64534 terrequinone A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64534 GO:1904799 regulation of neuron remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904799 regulation of neuronal remodeling|regulation of axon pruning Any process that modulates the frequency, rate or extent of neuron remodeling. GO:1904798 positive regulation of core promoter binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904798 up-regulation of core promoter binding|upregulation of core promoter binding|up regulation of core promoter binding|activation of core promoter binding Any process that activates or increases the frequency, rate or extent of core promoter binding. GO:1904797 negative regulation of core promoter binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904797 inhibition of core promoter binding|down regulation of core promoter binding|downregulation of core promoter binding|down-regulation of core promoter binding Any process that stops, prevents or reduces the frequency, rate or extent of core promoter binding. GO:1904796 regulation of core promoter binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904796 Any process that modulates the frequency, rate or extent of core promoter binding. GO:1904795 positive regulation of euchromatin binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904795 upregulation of euchromatin binding|up regulation of euchromatin binding|activation of euchromatin binding|up-regulation of euchromatin binding Any process that activates or increases the frequency, rate or extent of euchromatin binding. CHEBI:39573 (13R)-HPODE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39573 CHEBI:15599 cis-3-phenylcyclohexa-3,5-diene-1,2-diol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15599 CHEBI:15598 2-methylcitrate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15598 CHEBI:15595 malate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15595 CHEBI:15594 3-propylmalate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15594 CHEBI:15597 (2R)-2-O-phosphonato-3-sulfonatolactate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15597 CHEBI:15596 sinapic acid (S)-malate ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15596 CHEBI:15591 3-ethylmalic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15591 CHEBI:15590 2,3-dimethylmalic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15590 CHEBI:15593 3-oxalomalate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15593 CHEBI:15592 3-isopropylmalate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15592 CHEBI:327995 tyraminium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_327995 CHEBI:39567 12-hydroxylauric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39567 CHEBI:39564 (1R,6R)-2-succinyl-6-hydroxycyclohexa-2,4-diene-1-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39564 CHEBI:15569 N-(carboxyaminomethyl)urea biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15569 CHEBI:40538 benzylamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_40538 CHEBI:15566 (1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15566 CHEBI:15565 (1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15565 CHEBI:15568 (R)-2-halocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15568 CHEBI:15567 (1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15567 CHEBI:8113 phlorizin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_8113 CHEBI:15562 D-threo-isocitrate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15562 CHEBI:15561 cis-1,2-dihydronaphthalene-1,2-diol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15561 CHEBI:15564 (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15564 CHEBI:15563 D-erythro-isocitrate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15563 CHEBI:8116 phorbol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_8116 CHEBI:15560 (15Z)-12-oxophyto-10,15-dienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15560 CHEBI:15559 15-oxo-ETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15559 CHEBI:15558 15(S)-HETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15558 CHEBI:39547 (R)-carnitinium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39547 CHEBI:15555 prostaglandin D2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15555 CHEBI:15554 prostaglandin H2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15554 CHEBI:15557 15-dehydro-prostaglandin D2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15557 CHEBI:15556 15-dehydro-prostaglandin I2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15556 CHEBI:15551 prostaglandin E2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15551 CHEBI:15550 13,14-dihydro-15-oxo-prostaglandin E2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15550 CHEBI:15553 prostaglandin F2alpha biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15553 CHEBI:15552 prostaglandin I2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15552 CHEBI:15588 (R)-malate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15588 CHEBI:15587 (R)-3,3-dimethylmalic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15587 CHEBI:15589 (S)-malate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15589 CHEBI:15584 citramalic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15584 CHEBI:15583 (R)-2-ethylmalic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15583 CHEBI:15586 D-citramalic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15586 CHEBI:40519 adamantane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_40519 CHEBI:15580 (2E,6E,10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15580 CHEBI:15582 (2R,3S)-2,3-dimethylmalic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15582 CHEBI:15581 juvenile hormone II biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15581 CHEBI:8108 pheophytin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_8108 CHEBI:15577 (3beta,24R,24'R)-fucosterol epoxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15577 CHEBI:15576 (24R)-24-methylcycloart-25-en-3beta-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15576 CHEBI:15579 (25S)-5beta-spirostan-3beta-yl beta-D-glucoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15579 CHEBI:15578 (25S)-5beta-spirostan-3beta-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15578 CHEBI:15573 (2-aminoethyl)phosphonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15573 CHEBI:15572 2,3-dihydroxybenzoyl 5'-adenylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15572 CHEBI:8100 3-phenyllactate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_8100 CHEBI:15575 nuatigenin 3-beta-D-glucopyranoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15575 CHEBI:15574 nuatigenin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15574 CHEBI:15571 hydrazine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15571 CHEBI:15570 D-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15570 GO:1904719 positive regulation of AMPA glutamate receptor clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904719 up regulation of AMPA glutamate receptor clustering|positive regulation of AMPA receptor clustering|up regulation of AMPA receptor clustering|up regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|activation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|upregulation of AMPA glutamate receptor clustering|upregulation of AMPA receptor clustering|up-regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|up-regulation of AMPA glutamate receptor clustering|activation of AMPA glutamate receptor clustering|up-regulation of AMPA receptor clustering|activation of AMPA receptor clustering|upregulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering Any process that activates or increases the frequency, rate or extent of AMPA glutamate receptor clustering. GO:1904718 negative regulation of AMPA glutamate receptor clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904718 downregulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|downregulation of AMPA glutamate receptor clustering|downregulation of AMPA receptor clustering|down regulation of AMPA glutamate receptor clustering|inhibition of AMPA glutamate receptor clustering|down regulation of AMPA receptor clustering|inhibition of AMPA receptor clustering|negative regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|down-regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|inhibition of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|down-regulation of AMPA glutamate receptor clustering|down-regulation of AMPA receptor clustering|negative regulation of AMPA receptor clustering|down regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering Any process that stops, prevents or reduces the frequency, rate or extent of AMPA glutamate receptor clustering. GO:1904717 regulation of AMPA glutamate receptor clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904717 regulation of AMPA receptor clustering|regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering Any process that modulates the frequency, rate or extent of AMPA glutamate receptor clustering. GO:1904716 positive regulation of chaperone-mediated autophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904716 up regulation of chaperone-mediated autophagy|up regulation of CMA|positive regulation of CMA|activation of CMA|upregulation of chaperone-mediated autophagy|up-regulation of CMA|up-regulation of chaperone-mediated autophagy|activation of chaperone-mediated autophagy|upregulation of CMA Any process that activates or increases the frequency, rate or extent of chaperone-mediated autophagy. GO:1904715 negative regulation of chaperone-mediated autophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904715 down-regulation of chaperone-mediated autophagy|down regulation of CMA|downregulation of CMA|downregulation of chaperone-mediated autophagy|negative regulation of CMA|down regulation of chaperone-mediated autophagy|down-regulation of CMA|inhibition of chaperone-mediated autophagy|inhibition of CMA Any process that stops, prevents or reduces the frequency, rate or extent of chaperone-mediated autophagy. GO:1904714 regulation of chaperone-mediated autophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904714 regulation of CMA Any process that modulates the frequency, rate or extent of chaperone-mediated autophagy. GO:1904713 beta-catenin destruction complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1904713 23S APC complex binding|APC-Axin-1-beta-catenin complex binding|BDC binding|Axin-APC-beta-catenin-GSK3B complex binding|beta-catenin degradation complex binding Interacting selectively and non-covalently with a beta-catenin destruction complex. GO:1904712 positive regulation of Wnt-Frizzled-LRP5/6 complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904712 upregulation of Frizzled-LRP5/6 complex formation|up-regulation of WNT-FZD-LRP5 complex assembly|activation of WNT-FZD-LRP6 complex formation|positive regulation of Wnt-induced Frizzled-LRP5/6 complex assembly|activation of WNT-FZD-LRP5 complex formation|up regulation of Frizzled-LRP5/6 complex assembly|up-regulation of WNT-FZD-LRP6 complex assembly|upregulation of Wnt-FZD-LRP5/6 trimeric complex formation|up regulation of Wnt-induced Frizzled-LRP5/6 complex assembly|upregulation of Wnt-induced Frizzled-LRP5/6 complex formation|upregulation of Wnt-FZD-LRP5/6 trimeric complex assembly|positive regulation of WNT-FZD-LRP6 complex formation|positive regulation of Frizzled-LRP5/6 complex assembly|positive regulation of WNT-FZD-LRP5 complex formation|up regulation of WNT-FZD-LRP6 complex formation|up regulation of WNT-FZD-LRP5 complex formation|up regulation of Frizzled-LRP5/6 complex formation|upregulation of WNT-FZD-LRP5 complex assembly|upregulation of WNT-FZD-LRP6 complex assembly|up regulation of Wnt-FZD-LRP5/6 trimeric complex formation|upregulation of Frizzled-LRP5/6 complex assembly|positive regulation of Frizzled-LRP5/6 complex formation|upregulation of Wnt-induced Frizzled-LRP5/6 complex assembly|up regulation of Wnt-induced Frizzled-LRP5/6 complex formation|positive regulation of Wnt-FZD-LRP5/6 trimeric complex formation|activation of Wnt-FZD-LRP5/6 trimeric complex formation|up-regulation of Wnt-FZD-LRP5/6 trimeric complex assembly|activation of Wnt-FZD-LRP5/6 trimeric complex assembly|positive regulation of Wnt-induced Frizzled-LRP5/6 complex formation|activation of Frizzled-LRP5/6 complex formation|upregulation of WNT-FZD-LRP6 complex formation|upregulation of WNT-FZD-LRP5 complex formation|up regulation of WNT-FZD-LRP5 complex assembly|up-regulation of Frizzled-LRP5/6 complex assembly|activation of Wnt-induced Frizzled-LRP5/6 complex formation|up regulation of WNT-FZD-LRP6 complex assembly|up-regulation of Wnt-induced Frizzled-LRP5/6 complex assembly|activation of Frizzled-LRP5/6 complex assembly|positive regulation of WNT-FZD-LRP5 complex assembly|positive regulation of WNT-FZD-LRP6 complex assembly|up-regulation of Frizzled-LRP5/6 complex formation|up-regulation of Wnt-FZD-LRP5/6 trimeric complex formation|positive regulation of Wnt-FZD-LRP5/6 trimeric complex assembly|up-regulation of Wnt-induced Frizzled-LRP5/6 complex formation|up-regulation of WNT-FZD-LRP6 complex formation|up regulation of Wnt-FZD-LRP5/6 trimeric complex assembly|activation of WNT-FZD-LRP5 complex assembly|activation of Wnt-induced Frizzled-LRP5/6 complex assembly|activation of WNT-FZD-LRP6 complex assembly|up-regulation of WNT-FZD-LRP5 complex formation Any process that activates or increases the frequency, rate or extent of Wnt-Frizzled-LRP5/6 complex assembly. GO:1904711 regulation of Wnt-Frizzled-LRP5/6 complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904711 regulation of Wnt-FZD-LRP5/6 trimeric complex assembly|regulation of Frizzled-LRP5/6 complex formation|regulation of Wnt receptor complex assembly|regulation of Wnt-FZD-LRP5/6 trimeric complex formation|regulation of Wnt-induced Frizzled-LRP5/6 complex assembly|regulation of Wnt-induced Frizzled-LRP5/6 complex formation|regulation of WNT-FZD-LRP6 complex formation|regulation of Frizzled-LRP5/6 complex assembly|regulation of WNT-FZD-LRP5 complex formation|regulation of WNT-FZD-LRP5 complex assembly|regulation of WNT-FZD-LRP6 complex assembly Any process that modulates the frequency, rate or extent of Wnt-Frizzled-LRP5/6 complex assembly. GO:1904710 positive regulation of granulosa cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904710 up regulation of granulosa cell apoptotic process|up regulation of granulosa cell of ovary apoptotic process|activation of granulosa cell of ovary apoptotic process|activation of granulosa cell of ovary apoptosis|positive regulation of granulosa cell of ovary apoptotic process|upregulation of granulosa cell apoptosis|up-regulation of granulosa cell of ovary apoptosis|upregulation of granulosa cell apoptotic process|up-regulation of granulosa cell of ovary apoptotic process|up-regulation of granulosa cell apoptosis|upregulation of granulosa cell of ovary apoptosis|up-regulation of granulosa cell apoptotic process|activation of granulosa cell apoptosis|activation of granulosa cell apoptotic process|upregulation of granulosa cell of ovary apoptotic process|positive regulation of granulosa cell apoptosis|up regulation of granulosa cell apoptosis|up regulation of granulosa cell of ovary apoptosis|positive regulation of granulosa cell of ovary apoptosis Any process that activates or increases the frequency, rate or extent of granulosa cell apoptotic process. CHEBI:132245 (2R,3S)-glycosmisic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132245 CHEBI:132244 (E)-3-(indol-3-yl)acrylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132244 CHEBI:132247 (-)-DCA-CL biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132247 CHEBI:132246 all-trans-3,4-didehydroretinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132246 CHEBI:132249 (-)-DCA-CC biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132249 CHEBI:132248 N(4)-(N-acetyl-beta-D-glucosyl)-L-asparagine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132248 CHEBI:132240 ethylenediaminediacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132240 GO:1904729 regulation of intestinal lipid absorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904729 Any process that modulates the frequency, rate or extent of intestinal lipid absorption. GO:1904728 positive regulation of replicative senescence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904728 up-regulation of replicative senescence|activation of replicative senescence|up regulation of replicative senescence|upregulation of replicative senescence Any process that activates or increases the frequency, rate or extent of replicative senescence. GO:1904727 negative regulation of replicative senescence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904727 down-regulation of replicative senescence|downregulation of replicative senescence|down regulation of replicative senescence|inhibition of replicative senescence Any process that stops, prevents or reduces the frequency, rate or extent of replicative senescence. GO:1904726 regulation of replicative senescence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904726 Any process that modulates the frequency, rate or extent of replicative senescence. GO:1904725 obsolete TFIIB-class transcription factor binding involved in negative regulation of transcription biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1904725 TFIIB-class transcription factor binding involved in inhibition of transcription, DNA-dependent|TFIIB-class transcription factor binding involved in downregulation of gene-specific transcription|TFIIB-class transcription factor binding involved in down-regulation of transcription, DNA-dependent|TFIIB-class transcription factor binding involved in negative regulation of transcription, DNA-dependent|TFIIB-class transcription factor binding involved in down regulation of gene-specific transcription|TFIIB-class transcription factor binding involved in transcription repressor activity|TFIIB-class transcription factor binding involved in negative regulation of transcription, DNA-templated|TFIIB-class transcription factor binding involved in down regulation of transcription, DNA-dependent|TFIIB-class transcription factor binding involved in negative regulation of cellular transcription, DNA-dependent|TFIIB-class transcription factor binding involved in negative regulation of gene-specific transcription|TFIIB-class transcription factor binding involved in down-regulation of gene-specific transcription|TFIIB-class transcription factor binding involved in downregulation of transcription, DNA-dependent|TFIIB-class transcription factor binding involved in inhibition of gene-specific transcription OBSOLETE. Any TFIIB-class transcription factor binding that is involved in negative regulation of DNA-templated transcription. GO:1904724 tertiary granule lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1904724 membrane-enclosed lumen of tertiary granule|gelatinase granule membrane-enclosed lumen|membrane-enclosed lumen of gelatinase granule|tertiary granule membrane-enclosed lumen Any membrane-enclosed lumen that is part of a tertiary granule. GO:1904723 negative regulation of Wnt-Frizzled-LRP5/6 complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904723 downregulation of WNT-FZD-LRP5 complex assembly|inhibition of Wnt-induced Frizzled-LRP5/6 complex assembly|downregulation of WNT-FZD-LRP6 complex assembly|negative regulation of Wnt-FZD-LRP5/6 trimeric complex formation|down-regulation of Wnt-FZD-LRP5/6 trimeric complex formation|down-regulation of Wnt-induced Frizzled-LRP5/6 complex formation|negative regulation of Wnt-induced Frizzled-LRP5/6 complex formation|inhibition of WNT-FZD-LRP6 complex formation|negative regulation of Wnt-FZD-LRP5/6 trimeric complex assembly|down-regulation of Wnt-FZD-LRP5/6 trimeric complex assembly|inhibition of WNT-FZD-LRP5 complex formation|inhibition of Wnt-FZD-LRP5/6 trimeric complex formation|down-regulation of WNT-FZD-LRP5 complex assembly|negative regulation of WNT-FZD-LRP5 complex assembly|negative regulation of WNT-FZD-LRP6 complex assembly|down-regulation of WNT-FZD-LRP6 complex assembly|inhibition of Frizzled-LRP5/6 complex formation|negative regulation of Wnt-induced Frizzled-LRP5/6 complex assembly|down-regulation of Frizzled-LRP5/6 complex assembly|down-regulation of Wnt-induced Frizzled-LRP5/6 complex assembly|downregulation of Wnt-FZD-LRP5/6 trimeric complex assembly|inhibition of Wnt-induced Frizzled-LRP5/6 complex formation|negative regulation of WNT-FZD-LRP6 complex formation|down-regulation of WNT-FZD-LRP6 complex formation|negative regulation of WNT-FZD-LRP5 complex formation|down regulation of Frizzled-LRP5/6 complex formation|negative regulation of Frizzled-LRP5/6 complex assembly|down regulation of Wnt-FZD-LRP5/6 trimeric complex assembly|down-regulation of WNT-FZD-LRP5 complex formation|inhibition of Wnt-FZD-LRP5/6 trimeric complex assembly|downregulation of Frizzled-LRP5/6 complex assembly|inhibition of WNT-FZD-LRP5 complex assembly|downregulation of Wnt-induced Frizzled-LRP5/6 complex assembly|down regulation of Wnt-FZD-LRP5/6 trimeric complex formation|downregulation of Frizzled-LRP5/6 complex formation|down regulation of Wnt-induced Frizzled-LRP5/6 complex formation|inhibition of WNT-FZD-LRP6 complex assembly|down regulation of Frizzled-LRP5/6 complex assembly|downregulation of Wnt-FZD-LRP5/6 trimeric complex formation|down regulation of Wnt-induced Frizzled-LRP5/6 complex assembly|inhibition of Frizzled-LRP5/6 complex assembly|downregulation of WNT-FZD-LRP6 complex formation|downregulation of Wnt-induced Frizzled-LRP5/6 complex formation|downregulation of WNT-FZD-LRP5 complex formation|down regulation of WNT-FZD-LRP5 complex assembly|down regulation of WNT-FZD-LRP6 complex assembly|down regulation of WNT-FZD-LRP6 complex formation|down-regulation of Frizzled-LRP5/6 complex formation|down regulation of WNT-FZD-LRP5 complex formation|negative regulation of Frizzled-LRP5/6 complex formation Any process that stops, prevents or reduces the frequency, rate or extent of Wnt-Frizzled-LRP5/6 complex assembly. GO:1904722 obsolete positive regulation of mRNA endonucleolytic cleavage involved in unfolded protein response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904722 up regulation of mRNA endonucleolytic cleavage involved in unfolded protein response|activation of IRE1-mediated XBP-1 mRNA cleavage|activation of mRNA endonucleolytic cleavage involved in unfolded protein response|up-regulation of XBP1 mRNA cleavage|upregulation of HAC1-type intron splice site recognition and cleavage|up-regulation of HAC1 mRNA cleavage|up-regulation of IRE1-mediated XBP-1 mRNA cleavage|activation of XBP1 mRNA cleavage|up-regulation of mRNA endonucleolytic cleavage involved in unfolded protein response|activation of HAC1 mRNA cleavage|up regulation of HAC1-type intron splice site recognition and cleavage|positive regulation of XBP1 mRNA cleavage|up regulation of XBP1 mRNA cleavage|positive regulation of HAC1-type intron splice site recognition and cleavage|upregulation of IRE1-mediated XBP-1 mRNA cleavage|positive regulation of HAC1 mRNA cleavage|up regulation of HAC1 mRNA cleavage|activation of HAC1-type intron splice site recognition and cleavage|upregulation of mRNA endonucleolytic cleavage involved in unfolded protein response|up regulation of IRE1-mediated XBP-1 mRNA cleavage|upregulation of XBP1 mRNA cleavage|up-regulation of HAC1-type intron splice site recognition and cleavage|positive regulation of IRE1-mediated XBP-1 mRNA cleavage|upregulation of HAC1 mRNA cleavage OBSOLETE. Any process that activates or increases the frequency, rate or extent of mRNA endonucleolytic cleavage involved in unfolded protein response. GO:1904721 obsolete negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904721 inhibition of HAC1 mRNA cleavage|down regulation of HAC1-type intron splice site recognition and cleavage|down-regulation of mRNA endonucleolytic cleavage involved in unfolded protein response|negative regulation of XBP1 mRNA cleavage|down-regulation of XBP1 mRNA cleavage|downregulation of HAC1-type intron splice site recognition and cleavage|inhibition of IRE1-mediated XBP-1 mRNA cleavage|inhibition of mRNA endonucleolytic cleavage involved in unfolded protein response|down-regulation of HAC1 mRNA cleavage|negative regulation of HAC1 mRNA cleavage|downregulation of XBP1 mRNA cleavage|down regulation of IRE1-mediated XBP-1 mRNA cleavage|down-regulation of HAC1-type intron splice site recognition and cleavage|negative regulation of HAC1-type intron splice site recognition and cleavage|downregulation of HAC1 mRNA cleavage|downregulation of IRE1-mediated XBP-1 mRNA cleavage|down regulation of XBP1 mRNA cleavage|down regulation of mRNA endonucleolytic cleavage involved in unfolded protein response|down regulation of HAC1 mRNA cleavage|inhibition of XBP1 mRNA cleavage|downregulation of mRNA endonucleolytic cleavage involved in unfolded protein response|down-regulation of IRE1-mediated XBP-1 mRNA cleavage|negative regulation of IRE1-mediated XBP-1 mRNA cleavage|inhibition of HAC1-type intron splice site recognition and cleavage OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of mRNA endonucleolytic cleavage involved in unfolded protein response. GO:1904720 obsolete regulation of mRNA endonucleolytic cleavage involved in unfolded protein response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904720 regulation of HAC1-type intron splice site recognition and cleavage|regulation of IRE1-mediated XBP-1 mRNA cleavage|regulation of XBP1 mRNA cleavage|regulation of HAC1 mRNA cleavage OBSOLETE. Any process that modulates the frequency, rate or extent of mRNA endonucleolytic cleavage involved in unfolded protein response. CHEBI:132253 12,18-didecarboxysirohaem biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132253 CHEBI:132256 N-arachidonoyl-2-oxoserotonin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132256 CHEBI:132255 N-arachidonoylserotonin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132255 CHEBI:132258 (2E,5E)-tetradecadienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132258 CHEBI:132257 (2S,3R)-glycosmisic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132257 CHEBI:132259 all-trans-4-hydroxyretinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132259 CHEBI:132250 (+)-DCA-CC biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132250 CHEBI:132251 (+)-DCA-CL biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132251 GO:1904739 regulation of synapse organization by posttranscriptional regulation of gene expression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904739 regulation of synapse organization and biogenesis by posttranscriptional regulation of gene expression|regulation of synapse development by posttranscriptional regulation of gene expression|regulation of synapse morphogenesis by posttranscriptional regulation of gene expression|regulation of synapse organisation by posttranscriptional regulation of gene expression A posttranscriptional regulation of gene expression that results in regulation of synapse organization. GO:1904738 vascular associated smooth muscle cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904738 vascular smooth muscle cell migration The orderly movement of a vascular associated smooth muscle cell from one site to another. CHEBI:88494 epsilon-(gamma-glutamyl)lysine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88494 GO:1904737 positive regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904737 activation of fatty acid beta-oxidation using acyl-CoA dehydrogenase|up-regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase|up regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase|upregulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase Any process that activates or increases the frequency, rate or extent of fatty acid beta-oxidation using acyl-CoA dehydrogenase. GO:1904736 negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904736 down-regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase|downregulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase|down regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase|inhibition of fatty acid beta-oxidation using acyl-CoA dehydrogenase Any process that stops, prevents or reduces the frequency, rate or extent of fatty acid beta-oxidation using acyl-CoA dehydrogenase. GO:1904735 regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904735 Any process that modulates the frequency, rate or extent of fatty acid beta-oxidation using acyl-CoA dehydrogenase. CHEBI:132228 (13S,14S)-epoxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132228 GO:1904734 positive regulation of electron transfer activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904734 up regulation of rubredoxin|activation of redox-active disulfide bond electron carrier|upregulation of chloroplast-type ferredoxin|activation of electron transporter activity|positive regulation of 2Fe-2S electron transfer carrier|up regulation of 3Fe-4S/4Fe-4S electron transfer carrier|activation of polyferredoxin|upregulation of high-potential iron-sulfur carrier|positive regulation of dicluster bacterial-type ferredoxin|upregulation of amicyanin|up-regulation of bacterial-type ferredoxin|activation of mononuclear iron electron carrier|activation of electron carrier activity|up regulation of 2Fe-2S electron transfer carrier|up regulation of electron transfer flavoprotein, group I|positive regulation of electron transfer flavoprotein, group II|positive regulation of 3Fe-4S/4Fe-4S electron transfer carrier|up regulation of electron transporter activity|positive regulation of azurin|activation of monocluster bacterial-type ferredoxin|positive regulation of electron transfer flavoprotein, group I|upregulation of electron transfer flavoprotein|upregulation of electron acceptor activity|upregulation of copper electron carrier|up regulation of electron carrier activity|positive regulation of electron transporter activity|up regulation of azurin|up-regulation of thioredoxin-like 2Fe-2S ferredoxin|up regulation of electron transfer flavoprotein, group II|activation of small blue copper electron carrier|positive regulation of redox-active disulfide bond electron carrier|upregulation of adrenodoxin-type ferredoxin|positive regulation of polyferredoxin|activation of dicluster bacterial-type ferredoxin|upregulation of iron-sulfur electron transfer carrier|up regulation of redox-active disulfide bond electron carrier|up-regulation of mononuclear iron electron carrier|up regulation of electron carrier, chlorophyll electron transport system|up regulation of polyferredoxin|activation of 3Fe-4S/4Fe-4S electron transfer carrier|up regulation of electron donor activity|activation of electron transfer flavoprotein, group I|positive regulation of small blue copper electron carrier|upregulation of bacterial-type ferredoxin|upregulation of rubredoxin|up regulation of chloroplast-type ferredoxin|up-regulation of high-potential iron-sulfur carrier|up-regulation of monocluster bacterial-type ferredoxin|positive regulation of electron carrier, chlorophyll electron transport system|positive regulation of electron donor activity|activation of thioredoxin-like 2Fe-2S ferredoxin|up regulation of amicyanin|up-regulation of dicluster bacterial-type ferredoxin|upregulation of 2Fe-2S electron transfer carrier|up regulation of small blue copper electron carrier|positive regulation of chloroplast-type ferredoxin|positive regulation of amicyanin|up-regulation of electron transfer flavoprotein|up-regulation of electron acceptor activity|up-regulation of 3Fe-4S/4Fe-4S electron transfer carrier|activation of electron carrier, chlorophyll electron transport system|up regulation of copper electron carrier|upregulation of azurin|upregulation of electron transfer flavoprotein, group II|up-regulation of electron transfer flavoprotein, group I|positive regulation of thioredoxin-like 2Fe-2S ferredoxin|up regulation of adrenodoxin-type ferredoxin|activation of electron donor activity|up-regulation of electron transporter activity|activation of high-potential iron-sulfur carrier|upregulation of redox-active disulfide bond electron carrier|activation of chloroplast-type ferredoxin|upregulation of mononuclear iron electron carrier|up regulation of iron-sulfur electron transfer carrier|positive regulation of copper electron carrier|upregulation of polyferredoxin|positive regulation of adrenodoxin-type ferredoxin|up-regulation of electron carrier activity|up regulation of thioredoxin-like 2Fe-2S ferredoxin|activation of amicyanin|activation of electron acceptor activity|positive regulation of iron-sulfur electron transfer carrier|activation of electron transfer flavoprotein|upregulation of monocluster bacterial-type ferredoxin|up-regulation of rubredoxin|up regulation of bacterial-type ferredoxin|positive regulation of high-potential iron-sulfur carrier|up-regulation of 2Fe-2S electron transfer carrier|up-regulation of electron carrier, chlorophyll electron transport system|upregulation of dicluster bacterial-type ferredoxin|positive regulation of bacterial-type ferredoxin|up-regulation of electron donor activity|upregulation of small blue copper electron carrier|activation of copper electron carrier|up-regulation of chloroplast-type ferredoxin|activation of adrenodoxin-type ferredoxin|upregulation of 3Fe-4S/4Fe-4S electron transfer carrier|up regulation of high-potential iron-sulfur carrier|positive regulation of electron acceptor activity|up-regulation of azurin|up-regulation of electron transfer flavoprotein, group II|activation of iron-sulfur electron transfer carrier|positive regulation of electron transfer flavoprotein|upregulation of electron transfer flavoprotein, group I|up-regulation of amicyanin|upregulation of electron transporter activity|activation of rubredoxin|up-regulation of redox-active disulfide bond electron carrier|up regulation of electron transfer flavoprotein|up regulation of electron acceptor activity|up regulation of mononuclear iron electron carrier|activation of 2Fe-2S electron transfer carrier|activation of bacterial-type ferredoxin|up-regulation of polyferredoxin|upregulation of electron carrier activity|upregulation of thioredoxin-like 2Fe-2S ferredoxin|up-regulation of copper electron carrier|positive regulation of mononuclear iron electron carrier|up regulation of monocluster bacterial-type ferredoxin|up-regulation of adrenodoxin-type ferredoxin|activation of azurin|positive regulation of rubredoxin|upregulation of electron carrier, chlorophyll electron transport system|activation of electron transfer flavoprotein, group II|up-regulation of iron-sulfur electron transfer carrier|up regulation of dicluster bacterial-type ferredoxin|up-regulation of small blue copper electron carrier|upregulation of electron donor activity|positive regulation of monocluster bacterial-type ferredoxin Any process that activates or increases the frequency, rate or extent of electron transfer activity. GO:1904733 negative regulation of electron transfer activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904733 negative regulation of redox-active disulfide bond electron carrier|negative regulation of mononuclear iron electron carrier|down regulation of electron acceptor activity|down-regulation of redox-active disulfide bond electron carrier|down-regulation of mononuclear iron electron carrier|down regulation of electron transfer flavoprotein|inhibition of copper electron carrier|down regulation of electron carrier, chlorophyll electron transport system|negative regulation of polyferredoxin|down-regulation of polyferredoxin|inhibition of adrenodoxin-type ferredoxin|down regulation of electron donor activity|down-regulation of monocluster bacterial-type ferredoxin|inhibition of iron-sulfur electron transfer carrier|downregulation of rubredoxin|down regulation of chloroplast-type ferredoxin|negative regulation of monocluster bacterial-type ferredoxin|down regulation of amicyanin|inhibition of high-potential iron-sulfur carrier|negative regulation of dicluster bacterial-type ferredoxin|down-regulation of electron transporter activity|down-regulation of dicluster bacterial-type ferredoxin|negative regulation of electron transporter activity|downregulation of 2Fe-2S electron transfer carrier|downregulation of electron donor activity|inhibition of bacterial-type ferredoxin|downregulation of electron carrier, chlorophyll electron transport system|down-regulation of small blue copper electron carrier|negative regulation of small blue copper electron carrier|downregulation of chloroplast-type ferredoxin|down-regulation of electron carrier activity|negative regulation of 3Fe-4S/4Fe-4S electron transfer carrier|down regulation of rubredoxin|down-regulation of 3Fe-4S/4Fe-4S electron transfer carrier|negative regulation of electron transfer flavoprotein, group I|inhibition of electron acceptor activity|down regulation of copper electron carrier|downregulation of azurin|downregulation of amicyanin|down-regulation of electron transfer flavoprotein, group I|inhibition of electron transfer flavoprotein|downregulation of electron transfer flavoprotein, group II|down regulation of adrenodoxin-type ferredoxin|down regulation of 2Fe-2S electron transfer carrier|down regulation of iron-sulfur electron transfer carrier|downregulation of redox-active disulfide bond electron carrier|downregulation of polyferredoxin|inhibition of electron transporter activity|down regulation of azurin|down regulation of electron transfer flavoprotein, group II|downregulation of copper electron carrier|negative regulation of thioredoxin-like 2Fe-2S ferredoxin|down-regulation of thioredoxin-like 2Fe-2S ferredoxin|down regulation of bacterial-type ferredoxin|inhibition of electron carrier activity|downregulation of adrenodoxin-type ferredoxin|inhibition of mononuclear iron electron carrier|downregulation of iron-sulfur electron transfer carrier|inhibition of rubredoxin|down regulation of redox-active disulfide bond electron carrier|down-regulation of electron carrier, chlorophyll electron transport system|down regulation of polyferredoxin|negative regulation of electron carrier, chlorophyll electron transport system|negative regulation of electron donor activity|down-regulation of electron donor activity|downregulation of small blue copper electron carrier|inhibition of monocluster bacterial-type ferredoxin|negative regulation of chloroplast-type ferredoxin|down-regulation of chloroplast-type ferredoxin|inhibition of 2Fe-2S electron transfer carrier|inhibition of dicluster bacterial-type ferredoxin|down-regulation of amicyanin|downregulation of bacterial-type ferredoxin|negative regulation of amicyanin|negative regulation of high-potential iron-sulfur carrier|down-regulation of high-potential iron-sulfur carrier|down regulation of small blue copper electron carrier|inhibition of 3Fe-4S/4Fe-4S electron transfer carrier|inhibition of electron transfer flavoprotein, group II|inhibition of azurin|inhibition of electron transfer flavoprotein, group I|down-regulation of electron transfer flavoprotein|down-regulation of electron acceptor activity|negative regulation of electron acceptor activity|down regulation of mononuclear iron electron carrier|negative regulation of electron transfer flavoprotein|downregulation of thioredoxin-like 2Fe-2S ferredoxin|negative regulation of copper electron carrier|down-regulation of copper electron carrier|inhibition of redox-active disulfide bond electron carrier|down regulation of monocluster bacterial-type ferredoxin|inhibition of polyferredoxin|down-regulation of adrenodoxin-type ferredoxin|negative regulation of adrenodoxin-type ferredoxin|down-regulation of iron-sulfur electron transfer carrier|negative regulation of iron-sulfur electron transfer carrier|down regulation of electron transporter activity|down regulation of dicluster bacterial-type ferredoxin|downregulation of mononuclear iron electron carrier|down regulation of thioredoxin-like 2Fe-2S ferredoxin|down regulation of 3Fe-4S/4Fe-4S electron transfer carrier|downregulation of monocluster bacterial-type ferredoxin|down-regulation of bacterial-type ferredoxin|downregulation of high-potential iron-sulfur carrier|down-regulation of rubredoxin|inhibition of small blue copper electron carrier|negative regulation of rubredoxin|negative regulation of bacterial-type ferredoxin|down regulation of electron carrier activity|inhibition of electron carrier, chlorophyll electron transport system|inhibition of electron donor activity|down regulation of electron transfer flavoprotein, group I|downregulation of dicluster bacterial-type ferredoxin|negative regulation of 2Fe-2S electron transfer carrier|down-regulation of 2Fe-2S electron transfer carrier|inhibition of chloroplast-type ferredoxin|downregulation of electron transporter activity|downregulation of electron acceptor activity|inhibition of amicyanin|downregulation of electron transfer flavoprotein|downregulation of 3Fe-4S/4Fe-4S electron transfer carrier|downregulation of electron carrier activity|down regulation of high-potential iron-sulfur carrier|down-regulation of electron transfer flavoprotein, group II|negative regulation of electron transfer flavoprotein, group II|downregulation of electron transfer flavoprotein, group I|down-regulation of azurin|negative regulation of azurin|inhibition of thioredoxin-like 2Fe-2S ferredoxin Any process that stops, prevents or reduces the frequency, rate or extent of electron transfer activity. GO:1904732 regulation of electron transfer activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904732 regulation of electron carrier, chlorophyll electron transport system|regulation of electron donor activity|regulation of rubredoxin|regulation of chloroplast-type ferredoxin|regulation of amicyanin|regulation of 2Fe-2S electron transfer carrier|regulation of electron transfer flavoprotein, group II|regulation of azurin|regulation of copper electron carrier|regulation of adrenodoxin-type ferredoxin|regulation of redox-active disulfide bond electron carrier|regulation of iron-sulfur electron transfer carrier|regulation of polyferredoxin|regulation of bacterial-type ferredoxin|regulation of small blue copper electron carrier|regulation of mononuclear iron electron carrier|regulation of thioredoxin-like 2Fe-2S ferredoxin|regulation of monocluster bacterial-type ferredoxin|regulation of electron transporter activity|regulation of dicluster bacterial-type ferredoxin|regulation of high-potential iron-sulfur carrier|regulation of 3Fe-4S/4Fe-4S electron transfer carrier|regulation of electron transfer flavoprotein, group I|regulation of electron transfer flavoprotein|regulation of electron acceptor activity Any process that modulates the frequency, rate or extent of electron transfer activity. GO:1904731 positive regulation of intestinal lipid absorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904731 up-regulation of intestinal lipid absorption|upregulation of intestinal lipid absorption|up regulation of intestinal lipid absorption|activation of intestinal lipid absorption Any process that activates or increases the frequency, rate or extent of intestinal lipid absorption. GO:1904730 negative regulation of intestinal lipid absorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904730 inhibition of intestinal lipid absorption|down regulation of intestinal lipid absorption|downregulation of intestinal lipid absorption|down-regulation of intestinal lipid absorption Any process that stops, prevents or reduces the frequency, rate or extent of intestinal lipid absorption. CHEBI:132224 4-O-({poly[(2R)-1-glycerylphosphonato]}-[2R]-1-glycerylphosphonato)-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl undecaprenyl diphosphate polyanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132224 GO:1904749 regulation of protein localization to nucleolus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904749 regulation of protein localization in nucleolus|regulation of protein localisation in nucleolus|regulation of protein localisation to nucleolus Any process that modulates the frequency, rate or extent of protein localization to nucleolus. GO:1904748 regulation of apoptotic process involved in development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904748 regulation of apoptotic cell death involved in anatomical structure development|regulation of apoptosis involved in development of an anatomical structure|regulation of activation of apoptosis involved in development of an anatomical structure|regulation of commitment to apoptosis involved in anatomical structure development|regulation of apoptotic programmed cell death involved in development of an anatomical structure|regulation of apoptotic process involved in development of an anatomical structure|regulation of type I programmed cell death involved in development of an anatomical structure|regulation of induction of apoptosis involved in development of an anatomical structure|regulation of apoptosis activator activity involved in development of an anatomical structure|regulation of programmed cell death by apoptosis involved in anatomical structure development|regulation of induction of apoptosis by p53 involved in anatomical structure development|regulation of apoptotic program involved in anatomical structure development|regulation of apoptotic cell death involved in development of an anatomical structure|regulation of signaling (initiator) caspase activity involved in anatomical structure development|regulation of apoptosis signaling involved in anatomical structure development|regulation of commitment to apoptosis involved in development of an anatomical structure|regulation of apoptosis involved in anatomical structure development|regulation of programmed cell death by apoptosis involved in development of an anatomical structure|regulation of activation of apoptosis involved in anatomical structure development|regulation of apoptotic program involved in development of an anatomical structure|regulation of induction of apoptosis by p53 involved in development of an anatomical structure|regulation of apoptotic programmed cell death involved in anatomical structure development|regulation of signaling (initiator) caspase activity involved in development of an anatomical structure|regulation of apoptotic process involved in anatomical structure development|regulation of type I programmed cell death involved in anatomical structure development|regulation of apoptosis activator activity involved in anatomical structure development|regulation of induction of apoptosis involved in anatomical structure development|regulation of apoptosis signaling involved in development of an anatomical structure Any process that modulates the frequency, rate or extent of apoptotic process involved in development. GO:1904747 positive regulation of apoptotic process involved in development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904747 up regulation of apoptotic process involved in development of an anatomical structure|positive regulation of induction of apoptosis involved in anatomical structure development|upregulation of induction of apoptosis involved in development of an anatomical structure|upregulation of apoptosis activator activity involved in development of an anatomical structure|positive regulation of apoptosis activator activity involved in anatomical structure development|activation of apoptosis signaling involved in anatomical structure development|positive regulation of apoptotic program involved in anatomical structure development|positive regulation of induction of apoptosis by p53 involved in anatomical structure development|up-regulation of apoptosis involved in anatomical structure development|up-regulation of induction of apoptosis by p53 involved in development of an anatomical structure|up-regulation of activation of apoptosis involved in anatomical structure development|up-regulation of apoptotic program involved in development of an anatomical structure|upregulation of programmed cell death by apoptosis involved in anatomical structure development|up regulation of apoptotic program involved in anatomical structure development|up regulation of induction of apoptosis by p53 involved in anatomical structure development|activation of commitment to apoptosis involved in development of an anatomical structure|activation of type I programmed cell death involved in anatomical structure development|activation of signaling (initiator) caspase activity involved in development of an anatomical structure|upregulation of apoptosis involved in development of an anatomical structure|upregulation of activation of apoptosis involved in development of an anatomical structure|activation of induction of apoptosis involved in anatomical structure development|up regulation of apoptotic cell death involved in anatomical structure development|activation of apoptosis activator activity involved in anatomical structure development|up-regulation of programmed cell death by apoptosis involved in development of an anatomical structure|activation of apoptotic cell death involved in anatomical structure development|up-regulation of apoptotic programmed cell death involved in anatomical structure development|activation of apoptotic programmed cell death involved in anatomical structure development|positive regulation of apoptosis signaling involved in anatomical structure development|activation of apoptotic process involved in anatomical structure development|up-regulation of apoptosis signaling involved in development of an anatomical structure|positive regulation of apoptotic cell death involved in anatomical structure development|up-regulation of apoptotic process involved in development|up-regulation of apoptotic process involved in anatomical structure development|upregulation of signaling (initiator) caspase activity involved in anatomical structure development|upregulation of apoptotic cell death involved in development of an anatomical structure|activation of apoptosis involved in anatomical structure development|positive regulation of commitment to apoptosis involved in development of an anatomical structure|activation of apoptotic program involved in development of an anatomical structure|upregulation of commitment to apoptosis involved in anatomical structure development|activation of induction of apoptosis by p53 involved in development of an anatomical structure|up regulation of apoptosis signaling involved in anatomical structure development|activation of activation of apoptosis involved in anatomical structure development|up regulation of type I programmed cell death involved in development of an anatomical structure|upregulation of apoptotic programmed cell death involved in development of an anatomical structure|up regulation of commitment to apoptosis involved in development of an anatomical structure|upregulation of apoptotic process involved in development of an anatomical structure|up-regulation of type I programmed cell death involved in anatomical structure development|up regulation of apoptosis activator activity involved in development of an anatomical structure|up regulation of induction of apoptosis involved in development of an anatomical structure|up-regulation of signaling (initiator) caspase activity involved in development of an anatomical structure|positive regulation of type I programmed cell death involved in development of an anatomical structure|up-regulation of induction of apoptosis involved in anatomical structure development|up-regulation of apoptosis activator activity involved in anatomical structure development|positive regulation of apoptosis involved in anatomical structure development|positive regulation of apoptosis activator activity involved in development of an anatomical structure|positive regulation of induction of apoptosis involved in development of an anatomical structure|up regulation of programmed cell death by apoptosis involved in anatomical structure development|upregulation of induction of apoptosis by p53 involved in anatomical structure development|positive regulation of apoptotic program involved in development of an anatomical structure|upregulation of apoptotic program involved in anatomical structure development|positive regulation of activation of apoptosis involved in anatomical structure development|activation of apoptosis signaling involved in development of an anatomical structure|positive regulation of induction of apoptosis by p53 involved in development of an anatomical structure|up-regulation of apoptosis involved in development of an anatomical structure|up-regulation of activation of apoptosis involved in development of an anatomical structure|activation of programmed cell death by apoptosis involved in anatomical structure development|up regulation of apoptosis involved in anatomical structure development|up regulation of apoptotic program involved in development of an anatomical structure|up regulation of activation of apoptosis involved in anatomical structure development|up regulation of induction of apoptosis by p53 involved in development of an anatomical structure|positive regulation of programmed cell death by apoptosis involved in anatomical structure development|upregulation of programmed cell death by apoptosis involved in development of an anatomical structure|activation of type I programmed cell death involved in development of an anatomical structure|upregulation of apoptotic process involved in development|up regulation of signaling (initiator) caspase activity involved in anatomical structure development|positive regulation of apoptotic programmed cell death involved in anatomical structure development|activation of induction of apoptosis involved in development of an anatomical structure|up-regulation of commitment to apoptosis involved in anatomical structure development|activation of apoptosis activator activity involved in development of an anatomical structure|up regulation of apoptotic cell death involved in development of an anatomical structure|positive regulation of apoptotic process involved in anatomical structure development|positive regulation of apoptosis signaling involved in development of an anatomical structure|upregulation of apoptosis signaling involved in anatomical structure development|activation of apoptotic cell death involved in development of an anatomical structure|up-regulation of apoptotic programmed cell death involved in development of an anatomical structure|up-regulation of apoptotic cell death involved in anatomical structure development|activation of apoptotic programmed cell death involved in development of an anatomical structure|positive regulation of signaling (initiator) caspase activity involved in anatomical structure development|positive regulation of apoptotic cell death involved in development of an anatomical structure|up regulation of apoptotic programmed cell death involved in anatomical structure development|activation of apoptosis involved in development of an anatomical structure|activation of apoptotic process involved in development of an anatomical structure|up-regulation of apoptotic process involved in development of an anatomical structure|upregulation of signaling (initiator) caspase activity involved in development of an anatomical structure|upregulation of type I programmed cell death involved in anatomical structure development|upregulation of commitment to apoptosis involved in development of an anatomical structure|upregulation of apoptosis activator activity involved in anatomical structure development|up regulation of apoptotic process involved in anatomical structure development|activation of activation of apoptosis involved in development of an anatomical structure|upregulation of induction of apoptosis involved in anatomical structure development|up regulation of apoptosis signaling involved in development of an anatomical structure|up-regulation of apoptotic program involved in anatomical structure development|up-regulation of type I programmed cell death involved in development of an anatomical structure|up-regulation of induction of apoptosis by p53 involved in anatomical structure development|activation of commitment to apoptosis involved in anatomical structure development|up-regulation of apoptosis activator activity involved in development of an anatomical structure|up-regulation of induction of apoptosis involved in development of an anatomical structure|activation of signaling (initiator) caspase activity involved in anatomical structure development|positive regulation of apoptosis involved in development of an anatomical structure|upregulation of apoptosis involved in anatomical structure development|up regulation of programmed cell death by apoptosis involved in development of an anatomical structure|upregulation of apoptotic program involved in development of an anatomical structure|positive regulation of activation of apoptosis involved in development of an anatomical structure|upregulation of induction of apoptosis by p53 involved in development of an anatomical structure|upregulation of activation of apoptosis involved in anatomical structure development|up regulation of apoptotic process involved in development|up-regulation of programmed cell death by apoptosis involved in anatomical structure development|activation of programmed cell death by apoptosis involved in development of an anatomical structure|up regulation of apoptosis involved in development of an anatomical structure|positive regulation of programmed cell death by apoptosis involved in development of an anatomical structure|up regulation of activation of apoptosis involved in development of an anatomical structure|upregulation of apoptotic cell death involved in anatomical structure development|up-regulation of apoptosis signaling involved in anatomical structure development|activation of apoptotic process involved in development|positive regulation of commitment to apoptosis involved in anatomical structure development|activation of apoptotic program involved in anatomical structure development|activation of induction of apoptosis by p53 involved in anatomical structure development|up regulation of signaling (initiator) caspase activity involved in development of an anatomical structure|up regulation of type I programmed cell death involved in anatomical structure development|upregulation of apoptotic programmed cell death involved in anatomical structure development|up-regulation of commitment to apoptosis involved in development of an anatomical structure|positive regulation of apoptotic programmed cell death involved in development of an anatomical structure|upregulation of apoptotic process involved in anatomical structure development|upregulation of apoptosis signaling involved in development of an anatomical structure|positive regulation of apoptotic process involved in development of an anatomical structure|up regulation of commitment to apoptosis involved in anatomical structure development|up regulation of induction of apoptosis involved in anatomical structure development|up-regulation of signaling (initiator) caspase activity involved in anatomical structure development|up-regulation of apoptotic cell death involved in development of an anatomical structure|up regulation of apoptosis activator activity involved in anatomical structure development|upregulation of type I programmed cell death involved in development of an anatomical structure|positive regulation of type I programmed cell death involved in anatomical structure development|up regulation of apoptotic programmed cell death involved in development of an anatomical structure|positive regulation of signaling (initiator) caspase activity involved in development of an anatomical structure Any process that activates or increases the frequency, rate or extent of apoptotic process involved in development. GO:1904746 negative regulation of apoptotic process involved in development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904746 down regulation of apoptosis involved in development of an anatomical structure|downregulation of apoptotic programmed cell death involved in development of an anatomical structure|downregulation of commitment to apoptosis involved in anatomical structure development|downregulation of apoptotic cell death involved in anatomical structure development|down regulation of activation of apoptosis involved in development of an anatomical structure|downregulation of apoptotic process involved in development of an anatomical structure|inhibition of apoptosis signaling involved in development of an anatomical structure|down regulation of type I programmed cell death involved in development of an anatomical structure|down-regulation of apoptosis signaling involved in anatomical structure development|negative regulation of apoptosis signaling involved in anatomical structure development|inhibition of signaling (initiator) caspase activity involved in anatomical structure development|negative regulation of type I programmed cell death involved in anatomical structure development|down regulation of induction of apoptosis involved in development of an anatomical structure|down regulation of apoptosis activator activity involved in development of an anatomical structure|down-regulation of signaling (initiator) caspase activity involved in development of an anatomical structure|negative regulation of signaling (initiator) caspase activity involved in development of an anatomical structure|down-regulation of type I programmed cell death involved in anatomical structure development|down-regulation of apoptosis activator activity involved in anatomical structure development|negative regulation of commitment to apoptosis involved in development of an anatomical structure|negative regulation of induction of apoptosis involved in anatomical structure development|down-regulation of induction of apoptosis involved in anatomical structure development|down-regulation of commitment to apoptosis involved in development of an anatomical structure|negative regulation of apoptosis activator activity involved in anatomical structure development|down regulation of commitment to apoptosis involved in anatomical structure development|down regulation of programmed cell death by apoptosis involved in anatomical structure development|inhibition of programmed cell death by apoptosis involved in development of an anatomical structure|down regulation of apoptotic programmed cell death involved in development of an anatomical structure|downregulation of apoptotic program involved in anatomical structure development|downregulation of type I programmed cell death involved in development of an anatomical structure|down regulation of apoptotic process involved in development of an anatomical structure|inhibition of apoptotic process involved in development|downregulation of induction of apoptosis by p53 involved in anatomical structure development|downregulation of apoptosis activator activity involved in development of an anatomical structure|downregulation of induction of apoptosis involved in development of an anatomical structure|inhibition of apoptotic programmed cell death involved in development of an anatomical structure|inhibition of apoptosis involved in development of an anatomical structure|inhibition of apoptotic process involved in development of an anatomical structure|down-regulation of apoptosis involved in anatomical structure development|negative regulation of apoptosis involved in anatomical structure development|downregulation of programmed cell death by apoptosis involved in anatomical structure development|down regulation of apoptotic cell death involved in development of an anatomical structure|negative regulation of induction of apoptosis by p53 involved in development of an anatomical structure|down-regulation of apoptotic program involved in development of an anatomical structure|down-regulation of activation of apoptosis involved in anatomical structure development|inhibition of activation of apoptosis involved in development of an anatomical structure|down-regulation of induction of apoptosis by p53 involved in development of an anatomical structure|negative regulation of apoptotic program involved in development of an anatomical structure|negative regulation of activation of apoptosis involved in anatomical structure development|down regulation of signaling (initiator) caspase activity involved in anatomical structure development|negative regulation of apoptotic cell death involved in anatomical structure development|down regulation of apoptotic program involved in anatomical structure development|down-regulation of apoptotic cell death involved in anatomical structure development|down regulation of induction of apoptosis by p53 involved in anatomical structure development|downregulation of apoptosis signaling involved in anatomical structure development|negative regulation of apoptotic programmed cell death involved in anatomical structure development|inhibition of commitment to apoptosis involved in anatomical structure development|down-regulation of apoptotic programmed cell death involved in anatomical structure development|down-regulation of apoptotic process involved in anatomical structure development|downregulation of apoptotic cell death involved in development of an anatomical structure|negative regulation of apoptotic process involved in anatomical structure development|downregulation of commitment to apoptosis involved in development of an anatomical structure|negative regulation of apoptosis signaling involved in development of an anatomical structure|downregulation of signaling (initiator) caspase activity involved in anatomical structure development|down-regulation of apoptosis signaling involved in development of an anatomical structure|down-regulation of type I programmed cell death involved in development of an anatomical structure|inhibition of signaling (initiator) caspase activity involved in development of an anatomical structure|negative regulation of type I programmed cell death involved in development of an anatomical structure|inhibition of type I programmed cell death involved in anatomical structure development|down regulation of apoptosis signaling involved in anatomical structure development|negative regulation of induction of apoptosis involved in development of an anatomical structure|inhibition of induction of apoptosis involved in anatomical structure development|down-regulation of induction of apoptosis involved in development of an anatomical structure|negative regulation of apoptosis activator activity involved in development of an anatomical structure|inhibition of apoptosis activator activity involved in anatomical structure development|down-regulation of apoptosis activator activity involved in development of an anatomical structure|inhibition of apoptotic program involved in anatomical structure development|inhibition of apoptotic cell death involved in anatomical structure development|inhibition of induction of apoptosis by p53 involved in anatomical structure development|downregulation of apoptosis involved in anatomical structure development|down regulation of programmed cell death by apoptosis involved in development of an anatomical structure|down regulation of commitment to apoptosis involved in development of an anatomical structure|negative regulation of programmed cell death by apoptosis involved in anatomical structure development|down regulation of apoptotic process involved in development|downregulation of induction of apoptosis by p53 involved in development of an anatomical structure|down-regulation of programmed cell death by apoptosis involved in anatomical structure development|downregulation of activation of apoptosis involved in anatomical structure development|downregulation of apoptotic program involved in development of an anatomical structure|down-regulation of apoptosis involved in development of an anatomical structure|negative regulation of apoptosis involved in development of an anatomical structure|downregulation of apoptotic programmed cell death involved in anatomical structure development|down-regulation of activation of apoptosis involved in development of an anatomical structure|negative regulation of activation of apoptosis involved in development of an anatomical structure|down regulation of apoptosis involved in anatomical structure development|downregulation of programmed cell death by apoptosis involved in development of an anatomical structure|down regulation of activation of apoptosis involved in anatomical structure development|down regulation of signaling (initiator) caspase activity involved in development of an anatomical structure|down-regulation of apoptotic cell death involved in development of an anatomical structure|downregulation of apoptotic process involved in anatomical structure development|down regulation of induction of apoptosis by p53 involved in development of an anatomical structure|inhibition of apoptosis signaling involved in anatomical structure development|downregulation of apoptotic process involved in development|negative regulation of apoptotic cell death involved in development of an anatomical structure|down regulation of type I programmed cell death involved in anatomical structure development|down regulation of apoptotic program involved in development of an anatomical structure|down regulation of apoptosis activator activity involved in anatomical structure development|downregulation of apoptosis signaling involved in development of an anatomical structure|down-regulation of signaling (initiator) caspase activity involved in anatomical structure development|down regulation of induction of apoptosis involved in anatomical structure development|negative regulation of signaling (initiator) caspase activity involved in anatomical structure development|down-regulation of apoptotic programmed cell death involved in development of an anatomical structure|inhibition of commitment to apoptosis involved in development of an anatomical structure|negative regulation of commitment to apoptosis involved in anatomical structure development|negative regulation of apoptotic programmed cell death involved in development of an anatomical structure|down-regulation of commitment to apoptosis involved in anatomical structure development|inhibition of programmed cell death by apoptosis involved in anatomical structure development|down-regulation of apoptotic process involved in development of an anatomical structure|down regulation of apoptotic programmed cell death involved in anatomical structure development|negative regulation of apoptotic process involved in development of an anatomical structure|downregulation of signaling (initiator) caspase activity involved in development of an anatomical structure|down regulation of apoptotic process involved in anatomical structure development|downregulation of type I programmed cell death involved in anatomical structure development|down regulation of apoptosis signaling involved in development of an anatomical structure|inhibition of type I programmed cell death involved in development of an anatomical structure|downregulation of induction of apoptosis involved in anatomical structure development|downregulation of apoptosis activator activity involved in anatomical structure development|inhibition of apoptotic programmed cell death involved in anatomical structure development|inhibition of apoptotic process involved in anatomical structure development|inhibition of apoptosis activator activity involved in development of an anatomical structure|inhibition of induction of apoptosis involved in development of an anatomical structure|inhibition of apoptosis involved in anatomical structure development|down-regulation of induction of apoptosis by p53 involved in anatomical structure development|inhibition of induction of apoptosis by p53 involved in development of an anatomical structure|inhibition of activation of apoptosis involved in anatomical structure development|down regulation of apoptotic cell death involved in anatomical structure development|negative regulation of apoptotic program involved in anatomical structure development|downregulation of apoptosis involved in development of an anatomical structure|down-regulation of apoptotic program involved in anatomical structure development|inhibition of apoptotic program involved in development of an anatomical structure|negative regulation of induction of apoptosis by p53 involved in anatomical structure development|inhibition of apoptotic cell death involved in development of an anatomical structure|downregulation of activation of apoptosis involved in development of an anatomical structure|negative regulation of programmed cell death by apoptosis involved in development of an anatomical structure|down-regulation of programmed cell death by apoptosis involved in development of an anatomical structure|down-regulation of apoptotic process involved in development Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in development. GO:1904745 Atg1/ULK1 kinase complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904745 Atg1p signalling complex formation|Atg1p signalling complex assembly|ULK1-ATG13-FIP200 complex assembly|ATG1/ULK1 signaling complex formation|ATG1-ATG13 complex formation|ATG1 kinase complex formation|ULK1 signaling complex assembly|ULK1-ATG13-RB1CC1 complex assembly|ULK1 signaling complex formation|ULK1-ATG13-RB1CC1 complex formation|ATG1/ULK1 kinase complex formation|ATG1-ATG13 complex assembly|ATG1 kinase complex assembly|ATG1/ULK1 signaling complex assembly|ULK1-ATG13-FIP200 complex formation The aggregation, arrangement and bonding together of a set of components to form an Atg1/UKL1 kinase complex. GO:1904744 positive regulation of telomeric DNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904744 up-regulation of telomere binding|activation of telomere binding|up-regulation of telomeric repeat binding|up regulation of telomeric DNA binding|activation of telomeric repeat binding|activation of telomeric DNA binding|positive regulation of telomere binding|up regulation of telomere binding|positive regulation of telomeric repeat binding|up regulation of telomeric repeat binding|up-regulation of telomeric DNA binding|upregulation of telomere binding|upregulation of telomeric repeat binding|upregulation of telomeric DNA binding Any process that activates or increases the frequency, rate or extent of telomeric DNA binding. GO:1904743 negative regulation of telomeric DNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904743 down regulation of telomeric DNA binding|downregulation of telomeric DNA binding|down-regulation of telomere binding|negative regulation of telomere binding|down-regulation of telomeric repeat binding|down-regulation of telomeric DNA binding|negative regulation of telomeric repeat binding|downregulation of telomere binding|inhibition of telomeric DNA binding|downregulation of telomeric repeat binding|down regulation of telomere binding|inhibition of telomere binding|down regulation of telomeric repeat binding|inhibition of telomeric repeat binding Any process that stops, prevents or reduces the frequency, rate or extent of telomeric DNA binding. GO:1904742 regulation of telomeric DNA binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904742 regulation of telomere binding|regulation of telomeric repeat binding Any process that modulates the frequency, rate or extent of telomeric DNA binding. GO:1904741 obsolete positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by positive regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904741 positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by stimulation of transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by activation of global transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by up-regulation of transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by positive regulation of transcription from Pol II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by positive regulation of global transcription from Pol II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by up regulation of global transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by positive regulation of transcription from RNA polymerase II promoter, global|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by upregulation of transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by stimulation of global transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by upregulation of global transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by positive regulation of gene-specific transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by up regulation of transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by up-regulation of global transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by activation of transcription from RNA polymerase II promoter OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of filamentous growth of a population of unicellular organisms in response to starvation. GO:1904740 obsolete positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904740 positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by transcription from Pol II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by RNA polymerase II transcription factor activity|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by specific transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by gene-specific transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by general transcription from RNA polymerase II promoter OBSOLETE. A transcription from RNA polymerase II promoter that results in positive regulation of filamentous growth of a population of unicellular organisms in response to starvation. GO:1904750 negative regulation of protein localization to nucleolus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904750 down-regulation of protein localization to nucleolus|inhibition of protein localisation in nucleolus|inhibition of protein localization to nucleolus|down-regulation of protein localisation to nucleolus|negative regulation of protein localisation to nucleolus|down regulation of protein localization in nucleolus|downregulation of protein localization in nucleolus|inhibition of protein localisation to nucleolus|down regulation of protein localisation in nucleolus|down regulation of protein localization to nucleolus|downregulation of protein localisation in nucleolus|down-regulation of protein localization in nucleolus|negative regulation of protein localization in nucleolus|downregulation of protein localization to nucleolus|down regulation of protein localisation to nucleolus|inhibition of protein localization in nucleolus|down-regulation of protein localisation in nucleolus|negative regulation of protein localisation in nucleolus|downregulation of protein localisation to nucleolus Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleolus. CHEBI:132232 ethylenediaminetriacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132232 CHEBI:132233 1-phenylpropan-2-amine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132233 GO:1904759 protein localization to equatorial microtubule organizing center biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904759 protein localization to eMTOC|protein localisation in equatorial microtubule organizing center|protein localization in equatorial microtubule organizing center|protein localisation to equatorial microtubule organizing center A process in which a protein is transported to, or maintained in, a location within an equatorial microtubule organizing center. GO:1904758 protein localization to new growing cell tip biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904758 protein localization to new growing cell end|protein localisation to new growing cell tip|protein localization to post-new end take-off new cell tip|protein localization to post-NETO new cell tip|protein localization to post-NETO new cell end|protein localisation in new growing cell tip|protein localization to new cell tip after activation of bipolar cell growth|protein localization in new growing cell tip A process in which a protein is transported to, or maintained in, a location within a new growing cell tip. GO:1904757 positive regulation of gut granule assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904757 upregulation of gut granule assembly|up regulation of gut granule formation|activation of gut granule formation|positive regulation of gut granule formation|upregulation of gut granule biogenesis|up-regulation of gut granule assembly|activation of gut granule assembly|activation of gut granule biogenesis|up-regulation of gut granule biogenesis|up-regulation of gut granule formation|up regulation of gut granule assembly|upregulation of gut granule formation|positive regulation of gut granule biogenesis|up regulation of gut granule biogenesis Any process that activates or increases the frequency, rate or extent of gut granule assembly. GO:1904756 negative regulation of gut granule assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904756 downregulation of gut granule biogenesis|inhibition of gut granule assembly|downregulation of gut granule formation|down regulation of gut granule biogenesis|inhibition of gut granule biogenesis|negative regulation of gut granule formation|down-regulation of gut granule formation|down-regulation of gut granule assembly|inhibition of gut granule formation|negative regulation of gut granule biogenesis|down-regulation of gut granule biogenesis|downregulation of gut granule assembly|down regulation of gut granule formation|down regulation of gut granule assembly Any process that stops, prevents or reduces the frequency, rate or extent of gut granule assembly. GO:1904755 regulation of gut granule assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904755 regulation of gut granule formation|regulation of gut granule biogenesis Any process that modulates the frequency, rate or extent of gut granule assembly. GO:1904754 positive regulation of vascular associated smooth muscle cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904754 upregulation of vascular associated smooth muscle cell migration|up regulation of vascular smooth muscle cell migration|activation of vascular smooth muscle cell migration|positive regulation of vascular smooth muscle cell migration|up-regulation of vascular associated smooth muscle cell migration|activation of vascular associated smooth muscle cell migration|up-regulation of vascular smooth muscle cell migration|up regulation of vascular associated smooth muscle cell migration|upregulation of vascular smooth muscle cell migration Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell migration. GO:1904753 negative regulation of vascular associated smooth muscle cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904753 inhibition of vascular associated smooth muscle cell migration|down regulation of vascular smooth muscle cell migration|downregulation of vascular smooth muscle cell migration|negative regulation of vascular smooth muscle cell migration|down-regulation of vascular smooth muscle cell migration|down-regulation of vascular associated smooth muscle cell migration|inhibition of vascular smooth muscle cell migration|downregulation of vascular associated smooth muscle cell migration|down regulation of vascular associated smooth muscle cell migration Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell migration. GO:1904752 regulation of vascular associated smooth muscle cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904752 regulation of vascular smooth muscle cell migration Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell migration. GO:1904751 positive regulation of protein localization to nucleolus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904751 up regulation of protein localisation to nucleolus|positive regulation of protein localisation to nucleolus|activation of protein localisation to nucleolus|up-regulation of protein localisation in nucleolus|upregulation of protein localization in nucleolus|up-regulation of protein localization to nucleolus|upregulation of protein localisation in nucleolus|up-regulation of protein localisation to nucleolus|up regulation of protein localization in nucleolus|upregulation of protein localization to nucleolus|positive regulation of protein localization in nucleolus|activation of protein localization in nucleolus|up regulation of protein localisation in nucleolus|upregulation of protein localisation to nucleolus|activation of protein localisation in nucleolus|positive regulation of protein localisation in nucleolus|up regulation of protein localization to nucleolus|activation of protein localization to nucleolus|up-regulation of protein localization in nucleolus Any process that activates or increases the frequency, rate or extent of protein localization to nucleolus. GO:1904761 negative regulation of myofibroblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904761 down-regulation of myofibroblast differentiation|negative regulation of myofibroblast cell differentiation|down-regulation of myofibroblast cell differentiation|inhibition of myofibroblast differentiation|downregulation of myofibroblast cell differentiation|down regulation of myofibroblast cell differentiation|inhibition of myofibroblast cell differentiation|down regulation of myofibroblast differentiation|downregulation of myofibroblast differentiation Any process that stops, prevents or reduces the frequency, rate or extent of myofibroblast differentiation. GO:1904760 regulation of myofibroblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904760 regulation of myofibroblast cell differentiation Any process that modulates the frequency, rate or extent of myofibroblast differentiation. CHEBI:132201 11(S)-hydroxy-14(S),15(S)-hepoxilin A3(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132201 CHEBI:132200 11(S),15(S)-dihydroxy-14(R)-(S-glutathionyl)-5(Z),8(Z),12(E)-icosatrienoate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132200 CHEBI:132202 (2R)-CDP-glycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132202 GO:1904769 isopentadecanoic acid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1904769 13-methylmyristic acid binding Interacting selectively and non-covalently with isopentadecanoic acid. CHEBI:132218 5(S)-hydroperoxy-18(R)-hydroxy-(6E,8Z,11Z,14Z,16E)-icosapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132218 GO:1904768 all-trans-retinol binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1904768 Interacting selectively and non-covalently with all-trans-retinol. GO:1904767 octanoic acid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1904767 caprylic acid binding Interacting selectively and non-covalently with octanoic acid. GO:1904766 negative regulation of macroautophagy by TORC1 signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904766 negative regulation of autophagy in response to cellular starvation by TORC1 signaling|negative regulation of starvation-induced autophagy by TORC1 signaling|negative regulation of autophagy in response to cellular starvation by TORC1 signal transduction|negative regulation of non-specific autophagy by TORC1 signaling|negative regulation of starvation-induced autophagy by TORC1 signal transduction|negative regulation of non-specific autophagy by TORC1 signal transduction|negative regulation of macroautophagy by TORC1 signal transduction A TORC1 signaling that results in negative regulation of macroautophagy. CHEBI:132219 5(S),6(S)-epoxy-18(R)-hydroxy-(7E,9E,11Z,14Z,16E)-icosapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132219 GO:1904765 positive regulation of transcription from RNA polymerase II promoter in response to maltose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904765 stimulation of transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|activation of global transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|up-regulation of transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|positive regulation of global transcription from Pol II promoter involved in cellular response to maltose stimulus|positive regulation of transcription from RNA polymerase II promoter, global involved in cellular response to maltose stimulus|positive regulation of transcription from Pol II promoter involved in cellular response to maltose stimulus|up regulation of global transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|positive regulation of transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|upregulation of transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|upregulation of global transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|stimulation of global transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|up regulation of transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|up-regulation of global transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|activation of transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a maltose stimulus. GO:1904764 chaperone-mediated autophagy translocation complex disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904764 CMA receptor complex disassembly|chaperone-mediated autophagy receptor complex disassembly|CMA translocation complex disassembly The disaggregation of a chaperone-mediated autophagy translocation complex into its constituent components. GO:1904763 chaperone-mediated autophagy translocation complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904763 CMA translocation complex assembly|chaperone-mediated autophagy translocation complex formation|CMA receptor complex formation|chaperone-mediated autophagy receptor complex assembly|chaperone-mediated autophagy receptor complex formation|CMA translocation complex formation|CMA receptor complex assembly The aggregation, arrangement and bonding together of a set of components to form a chaperone-mediated autophagy translocation complex. GO:1904762 positive regulation of myofibroblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904762 positive regulation of myofibroblast cell differentiation|up regulation of myofibroblast cell differentiation|up-regulation of myofibroblast differentiation|upregulation of myofibroblast cell differentiation|upregulation of myofibroblast differentiation|up-regulation of myofibroblast cell differentiation|activation of myofibroblast cell differentiation|up regulation of myofibroblast differentiation|activation of myofibroblast differentiation Any process that activates or increases the frequency, rate or extent of myofibroblast differentiation. GO:1904772 response to tetrachloromethane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904772 response to carbon tetrachloride|response to CCL4 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrachloromethane stimulus. CHEBI:132210 N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl undecaprenyl diphosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132210 GO:1904771 obsolete cellular response to doxorubicin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904771 OBSOLETE. Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a doxorubicin stimulus. GO:1904770 intramembranous bone morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904770 membrane bone morphogenesis|intramembranous bones morphogenesis The developmental process by which an intramembranous bone is generated and organized. CHEBI:132211 4-O-[(2R)-1-glycerylphosphonato]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl undecaprenyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132211 GO:1904779 regulation of protein localization to centrosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904779 regulation of protein localisation to centrosome Any process that modulates the frequency, rate or extent of protein localization to centrosome. GO:1904778 positive regulation of protein localization to cell cortex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904778 upregulation of protein localization to cell cortex|upregulation of protein localisation to cell cortex|up regulation of protein localization to cell cortex|activation of protein localization to cell cortex|up regulation of protein localisation to cell cortex|activation of protein localisation to cell cortex|positive regulation of protein localisation to cell cortex|up-regulation of protein localization to cell cortex|up-regulation of protein localisation to cell cortex Any process that activates or increases the frequency, rate or extent of protein localization to cell cortex. GO:1904777 negative regulation of protein localization to cell cortex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904777 down regulation of protein localization to cell cortex|downregulation of protein localization to cell cortex|down regulation of protein localisation to cell cortex|downregulation of protein localisation to cell cortex|down-regulation of protein localization to cell cortex|inhibition of protein localization to cell cortex|down-regulation of protein localisation to cell cortex|negative regulation of protein localisation to cell cortex|inhibition of protein localisation to cell cortex Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell cortex. GO:1904776 regulation of protein localization to cell cortex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904776 regulation of protein localisation to cell cortex Any process that modulates the frequency, rate or extent of protein localization to cell cortex. GO:1904775 positive regulation of ubiquinone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904775 activation of ubiquinone formation|activation of coenzyme Q10 biosynthetic process|activation of coenzyme Q10 biosynthesis|activation of coenzyme Q8 biosynthetic process|activation of coenzyme Q8 biosynthesis|positive regulation of coenzyme Q biosynthetic process|positive regulation of coenzyme Q biosynthesis|activation of coenzyme Q biosynthetic process|activation of coenzyme Q biosynthesis|activation of coenzyme Q9 biosynthetic process|activation of coenzyme Q9 biosynthesis|up regulation of ubiquinone biosynthesis|positive regulation of ubiquinone anabolism|up regulation of ubiquinone biosynthetic process|positive regulation of coenzyme Q6 biosynthesis|positive regulation of coenzyme Q6 biosynthetic process|activation of ubiquinone biosynthesis|activation of ubiquinone biosynthetic process|positive regulation of ubiquinone biosynthesis|up regulation of ubiquinone anabolism|positive regulation of coenzyme Q8 biosynthetic process|up regulation of coenzyme Q6 biosynthesis|positive regulation of coenzyme Q8 biosynthesis|up regulation of coenzyme Q6 biosynthetic process|up-regulation of coenzyme Q10 biosynthetic process|up-regulation of coenzyme Q10 biosynthesis|positive regulation of ubiquinone synthesis|positive regulation of coenzyme Q9 biosynthesis|positive regulation of coenzyme Q9 biosynthetic process|up regulation of coenzyme Q8 biosynthesis|up regulation of coenzyme Q8 biosynthetic process|up regulation of coenzyme Q9 biosynthetic process|up regulation of ubiquinone synthesis|up regulation of coenzyme Q9 biosynthesis|positive regulation of ubiquinone formation|up-regulation of coenzyme Q biosynthetic process|up-regulation of coenzyme Q biosynthesis|up regulation of ubiquinone formation|upregulation of coenzyme Q10 biosynthesis|upregulation of coenzyme Q10 biosynthetic process|upregulation of ubiquinone anabolism|upregulation of coenzyme Q6 biosynthetic process|up-regulation of ubiquinone biosynthesis|upregulation of coenzyme Q6 biosynthesis|up-regulation of ubiquinone biosynthetic process|upregulation of coenzyme Q8 biosynthesis|upregulation of coenzyme Q8 biosynthetic process|upregulation of coenzyme Q9 biosynthetic process|upregulation of ubiquinone synthesis|upregulation of coenzyme Q9 biosynthesis|upregulation of coenzyme Q biosynthetic process|upregulation of coenzyme Q biosynthesis|upregulation of ubiquinone formation|up-regulation of ubiquinone anabolism|up-regulation of coenzyme Q6 biosynthetic process|activation of ubiquinone anabolism|up regulation of coenzyme Q10 biosynthesis|upregulation of ubiquinone biosynthesis|upregulation of ubiquinone biosynthetic process|up regulation of coenzyme Q10 biosynthetic process|up-regulation of coenzyme Q6 biosynthesis|positive regulation of coenzyme Q10 biosynthesis|up-regulation of coenzyme Q8 biosynthetic process|up-regulation of coenzyme Q8 biosynthesis|positive regulation of coenzyme Q10 biosynthetic process|up-regulation of coenzyme Q9 biosynthesis|up-regulation of coenzyme Q9 biosynthetic process|up-regulation of ubiquinone synthesis|activation of ubiquinone synthesis|up regulation of coenzyme Q biosynthesis|activation of coenzyme Q6 biosynthesis|activation of coenzyme Q6 biosynthetic process|up regulation of coenzyme Q biosynthetic process|up-regulation of ubiquinone formation Any process that activates or increases the frequency, rate or extent of ubiquinone biosynthetic process. GO:1904774 negative regulation of ubiquinone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904774 downregulation of ubiquinone biosynthesis|downregulation of ubiquinone biosynthetic process|down-regulation of coenzyme Q8 biosynthetic process|negative regulation of coenzyme Q8 biosynthetic process|down-regulation of coenzyme Q8 biosynthesis|negative regulation of coenzyme Q8 biosynthesis|negative regulation of coenzyme Q9 biosynthesis|negative regulation of coenzyme Q9 biosynthetic process|down-regulation of coenzyme Q9 biosynthetic process|down-regulation of coenzyme Q9 biosynthesis|down-regulation of ubiquinone synthesis|negative regulation of ubiquinone synthesis|down-regulation of coenzyme Q biosynthetic process|negative regulation of coenzyme Q biosynthetic process|negative regulation of coenzyme Q biosynthesis|down-regulation of coenzyme Q biosynthesis|down-regulation of ubiquinone formation|negative regulation of ubiquinone formation|downregulation of ubiquinone anabolism|downregulation of coenzyme Q6 biosynthetic process|downregulation of coenzyme Q6 biosynthesis|down-regulation of ubiquinone biosynthetic process|down-regulation of ubiquinone biosynthesis|negative regulation of ubiquinone biosynthesis|inhibition of coenzyme Q10 biosynthetic process|inhibition of coenzyme Q10 biosynthesis|downregulation of coenzyme Q8 biosynthetic process|downregulation of coenzyme Q8 biosynthesis|inhibition of coenzyme Q biosynthesis|downregulation of coenzyme Q9 biosynthesis|inhibition of coenzyme Q biosynthetic process|downregulation of coenzyme Q9 biosynthetic process|down regulation of coenzyme Q6 biosynthesis|down regulation of ubiquinone anabolism|downregulation of ubiquinone synthesis|down regulation of coenzyme Q6 biosynthetic process|inhibition of ubiquinone anabolism|down regulation of coenzyme Q8 biosynthesis|down regulation of coenzyme Q8 biosynthetic process|down regulation of coenzyme Q9 biosynthetic process|inhibition of ubiquinone biosynthesis|downregulation of ubiquinone formation|down regulation of coenzyme Q9 biosynthesis|inhibition of ubiquinone biosynthetic process|down regulation of ubiquinone synthesis|inhibition of ubiquinone synthesis|down regulation of coenzyme Q10 biosynthesis|down regulation of coenzyme Q10 biosynthetic process|down regulation of ubiquinone formation|inhibition of coenzyme Q6 biosynthetic process|inhibition of coenzyme Q6 biosynthesis|inhibition of ubiquinone formation|inhibition of coenzyme Q8 biosynthesis|downregulation of coenzyme Q10 biosynthesis|inhibition of coenzyme Q8 biosynthetic process|downregulation of coenzyme Q10 biosynthetic process|inhibition of coenzyme Q9 biosynthetic process|inhibition of coenzyme Q9 biosynthesis|down regulation of coenzyme Q biosynthesis|down regulation of coenzyme Q biosynthetic process|down regulation of ubiquinone biosynthesis|down regulation of ubiquinone biosynthetic process|downregulation of coenzyme Q biosynthetic process|downregulation of coenzyme Q biosynthesis|negative regulation of coenzyme Q10 biosynthetic process|down-regulation of coenzyme Q10 biosynthetic process|down-regulation of coenzyme Q10 biosynthesis|negative regulation of coenzyme Q10 biosynthesis|negative regulation of coenzyme Q6 biosynthesis|down-regulation of ubiquinone anabolism|negative regulation of ubiquinone anabolism|down-regulation of coenzyme Q6 biosynthesis|negative regulation of coenzyme Q6 biosynthetic process|down-regulation of coenzyme Q6 biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of ubiquinone biosynthetic process. GO:1904773 obsolete cellular response to tetrachloromethane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904773 cellular response to CCL4|cellular response to carbon tetrachloride OBSOLETE. Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrachloromethane stimulus. GO:1904783 positive regulation of NMDA glutamate receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904783 positive regulation of N-methyl-D-aspartate selective glutamate receptor activity|upregulation of NMDA glutamate receptor activity|up regulation of N-methyl-D-aspartate selective glutamate receptor activity|up-regulation of NMDA receptor|up-regulation of NMDA glutamate receptor activity|activation of NMDA glutamate receptor activity|upregulation of N-methyl-D-aspartate selective glutamate receptor activity|upregulation of NMDA receptor|up-regulation of N-methyl-D-aspartate selective glutamate receptor activity|activation of N-methyl-D-aspartate selective glutamate receptor activity|up regulation of NMDA glutamate receptor activity|up regulation of NMDA receptor|activation of NMDA receptor|positive regulation of NMDA receptor Any process that activates or increases the frequency, rate or extent of NMDA glutamate receptor activity. GO:1904782 negative regulation of NMDA glutamate receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904782 negative regulation of NMDA receptor|down-regulation of NMDA receptor|down regulation of NMDA glutamate receptor activity|inhibition of NMDA glutamate receptor activity|inhibition of NMDA receptor|downregulation of N-methyl-D-aspartate selective glutamate receptor activity|down regulation of N-methyl-D-aspartate selective glutamate receptor activity|inhibition of N-methyl-D-aspartate selective glutamate receptor activity|down regulation of NMDA receptor|down-regulation of NMDA glutamate receptor activity|downregulation of NMDA receptor|downregulation of NMDA glutamate receptor activity|negative regulation of N-methyl-D-aspartate selective glutamate receptor activity|down-regulation of N-methyl-D-aspartate selective glutamate receptor activity Any process that stops, prevents or reduces the frequency, rate or extent of NMDA glutamate receptor activity. GO:1904781 positive regulation of protein localization to centrosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904781 upregulation of protein localization to centrosome|up-regulation of protein localisation to centrosome|activation of protein localisation to centrosome|up-regulation of protein localization to centrosome|activation of protein localization to centrosome|positive regulation of protein localisation to centrosome|up regulation of protein localisation to centrosome|up regulation of protein localization to centrosome|upregulation of protein localisation to centrosome Any process that activates or increases the frequency, rate or extent of protein localization to centrosome. GO:1904780 negative regulation of protein localization to centrosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904780 negative regulation of protein localisation to centrosome|down-regulation of protein localisation to centrosome|down-regulation of protein localization to centrosome|downregulation of protein localisation to centrosome|down regulation of protein localisation to centrosome|inhibition of protein localisation to centrosome|downregulation of protein localization to centrosome|down regulation of protein localization to centrosome|inhibition of protein localization to centrosome Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to centrosome. CHEBI:39474 polyazaalkane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39474 CHEBI:8191 all-trans-phytoene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_8191 GO:1904789 regulation of mitotic actomyosin contractile ring maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904789 regulation of contractile ring maintenance involved in cell cycle cytokinesis involved in mitotic cell cycle|regulation of cytokinesis, contractile ring maintenance, involved in cytokinesis during cell cycle involved in mitotic cell cycle Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring maintenance. GO:1904788 obsolete positive regulation of induction of conjugation with cellular fusion by regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904788 positive regulation of induction of conjugation with cellular fusion by regulation of global transcription from Pol II promoter|positive regulation of induction of conjugation with cellular fusion by regulation of transcription from RNA polymerase II promoter, global|positive regulation of induction of conjugation with cellular fusion by regulation of gene-specific transcription from RNA polymerase II promoter|positive regulation of induction of conjugation with cellular fusion by global transcription regulation from Pol II promoter|positive regulation of induction of conjugation with cellular fusion by regulation of transcription from Pol II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in positive regulation of induction of conjugation with cellular fusion. GO:1904787 positive regulation of asymmetric protein localization involved in cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904787 up regulation of asymmetric protein localization involved in cell fate commitment|upregulation of asymmetric protein localisation involved in cell fate determination|upregulation of asymmetric protein localization resulting in cell fate commitment|upregulation of asymmetric protein localization involved in cell fate determination|up-regulation of cell fate commitment, asymmetric protein localization|upregulation of asymmetric protein localization involved in cell fate commitment|up regulation of asymmetric protein localisation involved in cell fate determination|positive regulation of asymmetric protein localisation involved in cell fate determination|activation of asymmetric protein localisation involved in cell fate determination|upregulation of cell fate commitment, asymmetric protein localization|up regulation of asymmetric protein localization involved in cell fate determination|up regulation of asymmetric protein localization resulting in cell fate commitment|up-regulation of asymmetric protein localization involved in cell fate commitment|positive regulation of asymmetric protein localization resulting in cell fate commitment|activation of asymmetric protein localization involved in cell fate commitment|activation of asymmetric protein localization resulting in cell fate commitment|activation of asymmetric protein localization involved in cell fate determination|up-regulation of asymmetric protein localisation involved in cell fate determination|up regulation of cell fate commitment, asymmetric protein localization|positive regulation of cell fate commitment, asymmetric protein localization|positive regulation of asymmetric protein localization involved in cell fate commitment|activation of cell fate commitment, asymmetric protein localization|up-regulation of asymmetric protein localization involved in cell fate determination|up-regulation of asymmetric protein localization resulting in cell fate commitment Any process that activates or increases the frequency, rate or extent of asymmetric protein localization involved in cell fate determination. GO:1904786 negative regulation of asymmetric protein localization involved in cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904786 negative regulation of cell fate commitment, asymmetric protein localization|down-regulation of cell fate commitment, asymmetric protein localization|downregulation of asymmetric protein localization involved in cell fate commitment|down regulation of asymmetric protein localisation involved in cell fate determination|down regulation of asymmetric protein localization involved in cell fate commitment|inhibition of cell fate commitment, asymmetric protein localization|downregulation of asymmetric protein localisation involved in cell fate determination|inhibition of asymmetric protein localization involved in cell fate commitment|down regulation of asymmetric protein localization resulting in cell fate commitment|down regulation of asymmetric protein localization involved in cell fate determination|downregulation of asymmetric protein localization resulting in cell fate commitment|downregulation of asymmetric protein localization involved in cell fate determination|negative regulation of asymmetric protein localisation involved in cell fate determination|down-regulation of asymmetric protein localisation involved in cell fate determination|down regulation of cell fate commitment, asymmetric protein localization|inhibition of asymmetric protein localisation involved in cell fate determination|negative regulation of asymmetric protein localization resulting in cell fate commitment|down-regulation of asymmetric protein localization resulting in cell fate commitment|down-regulation of asymmetric protein localization involved in cell fate determination|downregulation of cell fate commitment, asymmetric protein localization|down-regulation of asymmetric protein localization involved in cell fate commitment|negative regulation of asymmetric protein localization involved in cell fate commitment|inhibition of asymmetric protein localization resulting in cell fate commitment|inhibition of asymmetric protein localization involved in cell fate determination Any process that stops, prevents or reduces the frequency, rate or extent of asymmetric protein localization involved in cell fate determination. GO:1904785 regulation of asymmetric protein localization involved in cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904785 regulation of asymmetric protein localization involved in cell fate commitment|regulation of asymmetric protein localisation involved in cell fate determination|regulation of asymmetric protein localization resulting in cell fate commitment|regulation of cell fate commitment, asymmetric protein localization Any process that modulates the frequency, rate or extent of asymmetric protein localization involved in cell fate determination. CHEBI:40460 2'-O-methyladenosine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_40460 GO:1904784 NLRP1 inflammasome complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904784 NALP1 inflammasome complex assembly|NLRP1 inflammasome complex formation|NALP1 inflammasome complex formation The aggregation, arrangement and bonding together of a set of components to form a NLRP1 inflammasome complex. GO:1904794 negative regulation of euchromatin binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904794 down regulation of euchromatin binding|downregulation of euchromatin binding|down-regulation of euchromatin binding|inhibition of euchromatin binding Any process that stops, prevents or reduces the frequency, rate or extent of euchromatin binding. GO:1904793 regulation of euchromatin binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904793 Any process that modulates the frequency, rate or extent of euchromatin binding. GO:1904792 positive regulation of shelterin complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904792 positive regulation of shelterin complex formation|upregulation of telosome assembly|upregulation of Pot1 complex assembly|positive regulation of Pot1-Tpz1 complex assembly|up regulation of Pot1-Tpz1 complex assembly|up-regulation of shelterin complex formation|up regulation of telosome assembly|activation of telosome assembly|up regulation of Pot1 complex assembly|activation of Pot1 complex assembly|positive regulation of Pot1 complex assembly|upregulation of Pot1-Tpz1 complex assembly|upregulation of shelterin complex formation|up-regulation of telosome assembly|activation of Pot1-Tpz1 complex assembly|up-regulation of Pot1-Tpz1 complex assembly|up-regulation of Pot1 complex assembly|positive regulation of telosome assembly|up regulation of shelterin complex formation|activation of shelterin complex formation Any process that activates or increases the frequency, rate or extent of shelterin complex assembly. GO:1904791 negative regulation of shelterin complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904791 negative regulation of Pot1-Tpz1 complex assembly|down-regulation of Pot1-Tpz1 complex assembly|negative regulation of telosome assembly|down regulation of telosome assembly|down-regulation of shelterin complex formation|negative regulation of shelterin complex formation|downregulation of telosome assembly|down regulation of Pot1 complex assembly|downregulation of Pot1-Tpz1 complex assembly|inhibition of shelterin complex formation|downregulation of Pot1 complex assembly|down regulation of Pot1-Tpz1 complex assembly|inhibition of Pot1-Tpz1 complex assembly|down-regulation of telosome assembly|down-regulation of Pot1 complex assembly|negative regulation of Pot1 complex assembly|down regulation of shelterin complex formation|inhibition of telosome assembly|downregulation of shelterin complex formation|inhibition of Pot1 complex assembly Any process that stops, prevents or reduces the frequency, rate or extent of shelterin complex assembly. GO:1904790 regulation of shelterin complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904790 regulation of Pot1 complex assembly|regulation of Pot1-Tpz1 complex assembly|regulation of telosome assembly|regulation of shelterin complex formation Any process that modulates the frequency, rate or extent of shelterin complex assembly. CHEBI:39482 chloroolefin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39482 CHEBI:64423 phosphatidylcholine 34:4 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64423 CHEBI:64421 dehydroaustinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64421 CHEBI:64427 phosphatidyl-N,N-dimethylethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64427 CHEBI:64426 cyclitol ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64426 CHEBI:64424 phosphatidylcholine 34:3 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64424 CHEBI:64429 chanoclavine-I aldehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64429 CHEBI:64428 H group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64428 CHEBI:64433 phosphatidylcholine 36:2 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64433 CHEBI:64436 arugosin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64436 CHEBI:88414 (S)-2-methylbutanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88414 CHEBI:64448 arsonate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64448 CHEBI:64450 endocrocin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64450 CHEBI:64454 (+)-kotanin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64454 CHEBI:64459 biaryl biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64459 CHEBI:156263 O-(S-decanoylpantetheine-4-phosphoryl)serine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_156263 CHEBI:156262 O-(S-octanoylpantetheine-4-phosphoryl)serine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_156262 CHEBI:64462 8,8'-bicoumarins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64462 CHEBI:64461 bicoumarin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64461 CHEBI:64465 demethylkotanin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64465 CHEBI:132286 1-O-(11-hydroxyoleoyl)-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132286 CHEBI:132280 1-O-[(9R,10S)-epoxystearoyl]-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132280 CHEBI:132285 1-O-(8-hydroxyoleoyl)-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132285 CHEBI:156255 S-adenosyl-D-methionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_156255 CHEBI:64474 p-hydroxyphenyl lignin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64474 CHEBI:64473 orlandin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64473 CHEBI:64477 monolignol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64477 CHEBI:64476 syringal lignin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64476 CHEBI:64475 guaiacyl lignin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64475 CHEBI:132297 methamphetamine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132297 CHEBI:64479 O-(pantetheine-4'-phosphoryl)serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64479 CHEBI:64480 phosphatidylcholine O-38:4 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64480 CHEBI:64483 lysophosphatidylcholine 14:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64483 CHEBI:64482 phosphatidylcholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64482 CHEBI:64489 1-myristoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64489 CHEBI:88456 8,15-DiHETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88456 DDANAT:0000098 inner basal disc biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000098 Central portion of the basal disc. Composed of stalk cells. CHEBI:88457 14,15-EpETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88457 CHEBI:132265 (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132265 CHEBI:132264 5,10-dihydrophenazine-1,6-dicarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132264 CHEBI:132266 (10aS)-10,10a-dihydrophenazine-1-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132266 CHEBI:132269 (3E)-octenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132269 CHEBI:132261 (1R,5aS,6R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132261 CHEBI:132263 (5aS)-5,5a-dihydrophenazine-1,6-dicarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132263 CHEBI:132262 (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1,6-dicarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132262 GO:1904709 negative regulation of granulosa cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904709 inhibition of granulosa cell apoptosis|inhibition of granulosa cell apoptotic process|inhibition of granulosa cell of ovary apoptotic process|inhibition of granulosa cell of ovary apoptosis|down regulation of granulosa cell of ovary apoptosis|negative regulation of granulosa cell apoptosis|down-regulation of granulosa cell apoptosis|downregulation of granulosa cell of ovary apoptosis|down regulation of granulosa cell of ovary apoptotic process|down-regulation of granulosa cell apoptotic process|downregulation of granulosa cell of ovary apoptotic process|downregulation of granulosa cell apoptosis|down-regulation of granulosa cell of ovary apoptosis|negative regulation of granulosa cell of ovary apoptosis|down regulation of granulosa cell apoptosis|downregulation of granulosa cell apoptotic process|negative regulation of granulosa cell of ovary apoptotic process|down-regulation of granulosa cell of ovary apoptotic process|down regulation of granulosa cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of granulosa cell apoptotic process. GO:1904708 regulation of granulosa cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904708 regulation of granulosa cell of ovary apoptosis|regulation of granulosa cell of ovary apoptotic process|regulation of granulosa cell apoptosis Any process that modulates the frequency, rate or extent of granulosa cell apoptotic process. GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904707 up regulation of vascular smooth muscle cell proliferation|activation of vascular smooth muscle cell proliferation|upregulation of VSMC proliferation|up-regulation of VSMC proliferation|up-regulation of vascular smooth muscle cell proliferation|activation of VSMC proliferation|positive regulation of vascular smooth muscle cell proliferation|upregulation of vascular smooth muscle cell proliferation|positive regulation of VSMC proliferation|up regulation of VSMC proliferation Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell proliferation. CHEBI:64492 ferricrocin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64492 GO:1904706 negative regulation of vascular associated smooth muscle cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904706 downregulation of VSMC proliferation|downregulation of vascular smooth muscle cell proliferation|down regulation of VSMC proliferation|inhibition of VSMC proliferation|down-regulation of vascular smooth muscle cell proliferation|inhibition of vascular smooth muscle cell proliferation|negative regulation of VSMC proliferation|down-regulation of VSMC proliferation|negative regulation of vascular smooth muscle cell proliferation|down regulation of vascular smooth muscle cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell proliferation. GO:1904705 regulation of vascular associated smooth muscle cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904705 regulation of VSMC proliferation|regulation of vascular smooth muscle cell proliferation Any process that modulates the frequency, rate or extent of vascular smooth muscle cell proliferation. GO:1904704 positive regulation of protein localization to adherens junction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904704 up-regulation of protein localization in cell-cell adherens junction|up regulation of protein localisation to cell-cell adherens junction|positive regulation of protein localisation to cell-cell adherens junction|activation of protein localisation to cell-cell adherens junction|up-regulation of protein localisation in cell-cell adherens junction|upregulation of protein localization in cell-cell adherens junction|up-regulation of protein localization to cell-cell adherens junction|upregulation of protein localisation in cell-cell adherens junction|up-regulation of protein localisation to cell-cell adherens junction|upregulation of protein localization to cell-cell adherens junction|up regulation of protein localization in cell-cell adherens junction|positive regulation of protein localization in cell-cell adherens junction|activation of protein localization in cell-cell adherens junction|up regulation of protein localisation in cell-cell adherens junction|upregulation of protein localisation to cell-cell adherens junction|activation of protein localisation in cell-cell adherens junction|positive regulation of protein localisation in cell-cell adherens junction|up regulation of protein localization to cell-cell adherens junction|activation of protein localization to cell-cell adherens junction Any process that activates or increases the frequency, rate or extent of protein localization to adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments. GO:1904703 negative regulation of protein localization to adherens junction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904703 downregulation of protein localisation to cell-cell adherens junction|down-regulation of protein localization to cell-cell adherens junction|inhibition of protein localisation in cell-cell adherens junction|negative regulation of protein localisation to cell-cell adherens junction|down-regulation of protein localisation to cell-cell adherens junction|inhibition of protein localization to cell-cell adherens junction|down regulation of protein localization in cell-cell adherens junction|downregulation of protein localization in cell-cell adherens junction|inhibition of protein localisation to cell-cell adherens junction|down regulation of protein localisation in cell-cell adherens junction|down regulation of protein localization to cell-cell adherens junction|downregulation of protein localisation in cell-cell adherens junction|negative regulation of protein localization in cell-cell adherens junction|down-regulation of protein localization in cell-cell adherens junction|downregulation of protein localization to cell-cell adherens junction|down regulation of protein localisation to cell-cell adherens junction|down-regulation of protein localisation in cell-cell adherens junction|inhibition of protein localization in cell-cell adherens junction|negative regulation of protein localisation in cell-cell adherens junction Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments. CHEBI:64496 lysophosphatidylcholine O-16:0/0:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64496 GO:1904702 regulation of protein localization to adherens junction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904702 regulation of protein localization in cell-cell adherens junction|regulation of protein localisation in cell-cell adherens junction|regulation of protein localisation to cell-cell adherens junction Any process that modulates the frequency, rate or extent of protein localization to adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments. GO:1904701 Wnt-Frizzled-LRP5/6 complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904701 Frizzled-LRP5/6 complex formation|Wnt-FZD-LRP5/6 trimeric complex assembly|Wnt-FZD-LRP5/6 trimeric complex formation|Wnt-induced Frizzled-LRP5/6 complex formation|Wnt receptor complex assembly|Wnt-induced Frizzled-LRP5/6 complex assembly|WNT-FZD-LRP5 complex assembly|WNT-FZD-LRP6 complex assembly|WNT-FZD-LRP6 complex formation|WNT-FZD-LRP5 complex formation|Frizzled-LRP5/6 complex assembly The aggregation, arrangement and bonding together of a set of components to form a Wnt-Frizzled-LRP5/6 complex. CHEBI:64494 tatiopterin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64494 GO:1904700 granulosa cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904700 granulosa cell apoptosis|granulosa cell of ovary apoptosis|granulosa cell of ovary apoptotic process Any apoptotic process in a granulosa cell. CHEBI:64493 sarcinapterin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64493 DDANAT:0000088 prestalk A region biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000088 pstA region Anterior-most region of the prestalk zone characterized by high expression of the ecmA gene directed by the proximal part of its promoter (ecmA promoter). DDANAT:0000087 prestalk region biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000087 pst region The prestalk region is located at the most apical part of the organism. It consists of about one quarter of the cells. CHEBI:64499 shamixanthone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64499 CHEBI:64497 cspyrone B1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64497 DDANAT:0000089 basal disc biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000089 Conical-shaped structure that anchors the stalk to the substratum. Composed of anterior-like cells. CHEBI:132276 (11S,12R)-EET biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132276 DDANAT:0000094 sorus biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000094 spore head Ovoid structure supported by the stalk and that contains the spores. CHEBI:132275 (14R,15S)-EET biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132275 CHEBI:132278 1-O-[(9S,10R)-epoxystearoyl]-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132278 CHEBI:132277 (11R,12S)-EET biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132277 DDANAT:0000091 prestalk AB core region biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000091 prestalk AB region|pstAB region Cone-shaped area of the prestalk zone that occupies a core among the pstA region. Cells of the pstAB region express both the ecmA and ecmB genes. DDANAT:0000093 stalk biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000093 sorophore Tubular structure that consists of cellulose-covered cells stacked on top of each other and surrounded by an acellular stalk tube composed of cellulose and glycoprotein. CHEBI:132271 (2E,5Z)-octadienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132271 CHEBI:132274 (14S,15R)-EET biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132274 CHEBI:74622 15-oxo-beta-bilirubin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74622 CHEBI:25699 organic ion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25699 CHEBI:25698 ether biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_25698 CHEBI:74621 5-oxo-delta-bilirubin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74621 CHEBI:25697 organic cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25697 CHEBI:25696 organic anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25696 CHEBI:74628 3-vinylbacteriochlorophyllide a biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74628 CHEBI:25690 ommatin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25690 CHEBI:25693 organic heteromonocyclic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25693 CHEBI:25692 ommochrome biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25692 CHEBI:11047 (S)-3-hydroxybutyrate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_11047 CL:1000334 enterocyte of epithelium of small intestine biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000334 An enterocyte that is part of the epithelium of small intestine. UBERON:0012437 epithelial-mesenchymal boundary biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012437 A anatomical line that adjacent_to a epithelium and adjacent_to a mesenchyme. CHEBI:74620 15-demethylaclacinomycin T biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74620 CHEBI:11041 (S)-3-(4-oxo-4,5-dihydro-1H-imidazol-5-yl)propanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_11041 CHEBI:74637 N(6)-L-threonylcarbamoyladenine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74637 CHEBI:50648 9-cis-retinoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50648 CHEBI:74636 N(6)-L-threonylcarbamoyladenine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74636 CHEBI:50646 bone density conservation agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50646 CHEBI:74638 N(6)-dimethylallyladenine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74638 UBERON:0012430 tunica fibrosa of eyeball biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012430 corneosclera|fibrous tunic|fibrous layer of eyeball|tunica fibrosa The sclera and cornea form the fibrous tunic of the bulb of the eye; the sclera is opaque, and constitutes the posterior five-sixths of the tunic; the cornea is transparent, and forms the anterior sixth. UBERON:0036422 wall of pulmonary artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036422 pulmonary arterial wall CL:1000322 pancreatic goblet cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000322 goblet cell of epithelium of pancreatic duct A goblet cell that is part of the epithelium of pancreatic duct. CL:1000320 large intestine goblet cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000320 goblet cell of epithelium of large intestine A goblet cell that is part of the epithelium of large intestine. CHEBI:35026 triethylamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35026 UBERON:0012425 striated border microvillus layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012425 striated border A microvillus layer that is striated and found in the intestine. UBERON:0012429 hematopoietic tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012429 hematopoietic tissue|textus haemopoieticus|bone marrow tissue|hemopoietic tissue|haemopoietic tissue Blood-forming tissue, consisting of reticular fibers and cells. CHEBI:35020 tributyrin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35020 CHEBI:74631 cysteamine S-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74631 CHEBI:74630 glycosyloxyisoflavone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74630 CHEBI:25676 oligopeptide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25676 CHEBI:49643 (2R)-3-HYDROXY-2-METHYLPROPANOIC ACID biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49643 CHEBI:74643 2-thio-N(6)-dimethylallyladenine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74643 CHEBI:74646 2-methylthio-N(6)-dimethylallyladenine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74646 CHEBI:50630 cyclooxygenase 1 inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50630 CHEBI:74645 2-methylthio-N(6)-dimethylallyladenine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74645 CHEBI:74648 2-thio-N(6)-L-threonylcarbamoyladenine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74648 CHEBI:74649 2-thio-N(6)-L-threonylcarbamoyladenine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74649 UBERON:0012423 layer of microvilli biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012423 microvillus|microvilli A layer of microvilli, Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments[GO,modified] CHEBI:60001 pelargonidin 3-O-rutinoside 5-O-beta-D-glucoside betaine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60001 CHEBI:60000 1-acyl-2-linoleoyl-sn-glycero-3-phosphocholine betaine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60000 CHEBI:60002 D-glycero-D-manno-heptose 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60002 UBERON:0012416 respiratory system arterial smooth muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012416 CHEBI:60005 3-amino-4-hydroxybenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60005 CHEBI:60004 mixture biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60004 CHEBI:60007 sulfoglycolithocholate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60007 CHEBI:60006 laricitrin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60006 CHEBI:60009 UDP-6-sulfoquinovose(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60009 UBERON:0012418 respiratory system venous smooth muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012418 A smooth muscle tissue that is part of a respiratory system venous blood vessel. CHEBI:60008 glycolithocholate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60008 CHEBI:11060 (S)-carnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_11060 CHEBI:74640 N-acetyl-L-tryptophan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74640 CHEBI:74642 2-thio-N(6)-dimethylallyladenine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74642 CHEBI:74655 7-methylguanosine 5'-triphosphate group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74655 CHEBI:50621 gamma-glutamylalanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50621 CHEBI:74656 O(4)-phosphonato-D-tyrosine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74656 CHEBI:50626 2-hydroxyhexadecanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50626 CHEBI:49637 hydrogen atom biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49637 CHEBI:74659 N(2),N(2),N(7)-trimethylguanosine 5'-triphosphate(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74659 CHEBI:74658 N(2),N(2),N(7)-trimethylguanosine 5'-triphosphate group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74658 UBERON:0036441 wall of uterine tube biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036441 wall of oviduct|wall of fallopian tube|uterine tube wall CHEBI:50629 cyclooxygenase 2 inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50629 CHEBI:50627 EC 3.2.1.1 (alpha-amylase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50627 CL:1000349 basal cell of epithelium of bronchus biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000349 basal cell of bronchus A basal cell found in the bronchus epithelium. CL:1000347 vacuolar absorptive cell of epithelium of colon biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000347 A columnar cell of the colon that is part of the colonic epithelium. CHEBI:25681 omega-3 fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25681 CHEBI:60014 3'-O-methyltricetin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60014 CHEBI:60016 3',5'-di-O-methyltricetin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60016 CHEBI:60015 2,3-dehydroacyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60015 CHEBI:35008 tetralin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35008 CHEBI:74650 2-methylthio-N(6)-L-threonylcarbamoyladenine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74650 CHEBI:74653 3-thio-L-aspartic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74653 CHEBI:74666 (12Z,15Z,18Z,21Z)-3-oxotetracosatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74666 CHEBI:74665 (10Z,13Z,16Z)-3-oxodocosatrienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74665 CHEBI:74668 N(2),N(2),N(7)-trimethylguanosine 5'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74668 CHEBI:74667 1-oleoyl-2-palmitoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74667 UBERON:0012482 submucosa of cloaca biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012482 cloaca submucosa|cloacal submucosa A submucosa that is part of a cloaca [Automatically generated definition]. CHEBI:74669 1,2-dioleoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74669 UBERON:0012481 cloacal epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012481 cloacal endoderm An epithelium that is part of a cloaca. UBERON:0012480 cloacal mucosa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012480 cloaca mucosa|mucosa of organ of cloaca|mucosa of cloaca|mucous membrane of cloaca|cloaca mucosa of organ|cloaca mucous membrane|cloaca organ mucosa|cloacal mucous membrane|organ mucosa of cloaca A mucosa that is part of a cloaca [Automatically generated definition]. CHEBI:50613 (S)-2-hydroxybutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50613 CHEBI:25656 octose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25656 CHEBI:50612 (R)-2-hydroxybutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50612 UBERON:0012486 muscle layer of cloaca biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012486 muscularis externa of cloaca|smooth muscle of cloaca A muscular coat that is part of a cloaca. UBERON:0012485 cloacal villus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012485 cloacal villi CHEBI:11009 (R)-3-phenyllactate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_11009 UBERON:0012483 serosa of cloaca biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012483 cloacal serosa|serous membrane of cloaca|cloaca serosa|cloaca serous membrane|visceral peritoneum of cloaca A serous membrane that is part of a cloaca [Automatically generated definition]. CHEBI:50616 iminoaspartic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50616 UBERON:0012489 muscle layer of colon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012489 muscularis externa of colon|colon muscularis|muscular layer of colon|tunica muscularis coli|colonic muscularis propria|muscular coat of colon A muscular coat that is part of a colon. CHEBI:60020 3',4',5'-O-trimethyltricetin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60020 CHEBI:60023 CoA-glutathione(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60023 UBERON:0012488 muscle layer of duodenum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012488 smooth muscle of duodenum|muscularis propria of duodenum|muscularis externa of duodenum|duodenal muscularis propria A muscular coat that is part of a duodenum. UBERON:0012487 vaginal sphincter biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012487 sphincter of vagina A sphincter muscle that is part of a vagina. CHEBI:60025 (5Z,7E,9E,14Z,17Z)-icosapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60025 CHEBI:60027 polymer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60027 CHEBI:60029 homopolymer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60029 CHEBI:74662 (10Z,13Z,16Z,19Z)-docosatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74662 CHEBI:74663 (11Z,14Z,17Z,20Z,23Z)-3-oxohexacosapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74663 CHEBI:74677 5-aminomethyl-2-thiouridine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74677 CHEBI:74676 N(6)-methyladenosine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74676 CHEBI:74679 5-methylaminomethyl-2-thiouridine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74679 CHEBI:74678 5-aminomethyl-2-thiouridine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74678 CHEBI:50604 5-(methylsulfanyl)-2,3-dioxopentyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50604 CHEBI:50602 precorrin-2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50602 CHEBI:50601 N(alpha)-methyl-L-histidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50601 UBERON:0012475 skeleton of pectoral complex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012475 upper limb skeleton|set of bones of upper limb|skeleton of anterior limb/fin and girdle|pectoral complex skeleton|ossa membri superioris|bones of upper limb The collection of all skeletal elements in a pectoral complex - i.e. the combination of free limb or fin plus pectoral girdle. CHEBI:50608 (2S)-2-hydroxy-3-oxobutyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50608 CHEBI:50606 2-hydroxy-3-oxobutyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50606 CHEBI:50605 2-hydroxy-5-(methylsulfanyl)-3-oxopent-1-enyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50605 CHEBI:60032 undecaprenyldiphosphonato-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-L-lysyl-D-alanyl-D-alanine(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60032 UBERON:0012478 cloacal gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012478 A gland that is part of a cloaca. CHEBI:25661 oleandomycins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25661 UBERON:0012477 dorsal part of neck biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012477 nuchal region|nape|posterior part of neck|regio cervicalis posterior|nucha|posterior neck region|hindneck|nape of neck|back of neck|neck back|posterior cervical region The posterior region of the neck, including the suboccipital region. UBERON:0012476 skeleton of pelvic complex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012476 pelvic complex skeleton|set of bones of lower limb|lower limb skeleton|ossa membri inferioris|skeleton of posterior limb/fin and girdle|bones of lower limb The collection of all skeletal elements in a pelvic complex - i.e. the combination of free limb or fin plus pelvic girdle. CHEBI:60033 lipid II(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60033 CHEBI:60038 flavonoid oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60038 UBERON:0012469 external anal region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012469 CHEBI:60039 L-proline zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60039 CHEBI:74671 1-oleoyl-2-arachidonoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74671 CHEBI:74670 1-oleoyl-2-linoleoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74670 CHEBI:74673 5,6-dihydrouridine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74673 CHEBI:74672 5,6-dihydrouridine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74672 CHEBI:74675 5-methyluridine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74675 CHEBI:74674 2'-O-methylguanosine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74674 CHEBI:25633 octadecatrienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25633 CHEBI:49601 Fe2S2 iron-sulfur cluster biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49601 CHEBI:25637 octadienoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25637 CHEBI:49603 lapatinib biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49603 CHEBI:25636 octadienediol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25636 CHEBI:25635 octadecenynoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25635 CHEBI:25634 octadecenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25634 UBERON:0012464 cloacal vent biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012464 vent|cloacal opening|cloacal orifice The opening of the cloacal chamber to the outside of the organism. Birds maintain a single cloacal opening throughout their lives. UBERON:0012463 cloacal lumen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012463 cloacal chamber|cloaca lumen A anatomical space that is enclosed by a cloaca. CHEBI:60041 cis-3-hydroxy-L-proline zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60041 CHEBI:60040 alpha-N-acetylneuraminyl-(2->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60040 CHEBI:60043 5'-acylphosphoadenosine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60043 UBERON:0012468 anal tooth biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012468 calcified anal papilla|perianal tooth|anal teeth|cloacal tooth Triangular calcified papillae (often five) placed radially around the anus of some Holothuriidae UBERON:0012467 enclosed anatomical space biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012467 closed anatomical space An anatomical space with no opening to another space or to the exterior. CHEBI:60045 tricetin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60045 UBERON:0012466 extraembryonic cavity biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012466 extraembryonic cavities CL:1000313 gastric goblet cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000313 goblet cell of epithelium of stomach A goblet cell that is part of the epithelium of stomach. UBERON:0012465 lumen of terminal part of digestive tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012465 A anatomical space that is enclosed by a terminal part of digestive tract. CHEBI:60047 N-acetyl-D-glucosaminyl-1-diphospho-ditrans,polycis-undecaprenol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60047 CL:1000312 bronchial goblet cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000312 goblet cell of epithelium of bronchus A goblet cell that is part of the epithelium of bronchus. CHEBI:60049 cobalt-sirohydrochlorin(8-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60049 CHEBI:60048 pelargonidin 3-O-rutinoside betaine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60048 CHEBI:11022 (S)-4-amino-5-oxopentanoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_11022 CHEBI:74680 5-methylaminomethyl-2-thiouridine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74680 CHEBI:25639 octadienol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25639 CHEBI:74681 2'-O-methyladenosine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74681 CHEBI:74685 2'-O-methyluridine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74685 CHEBI:25646 octanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_25646 UBERON:0012453 nerve ending biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012453 nerve ending Specialized terminations of peripheral neurons. Nerve endings include NEUROEFFECTOR JUNCTION(s) by which neurons activate target organs and sensory receptors (see RECEPTORS, SENSORY) which transduce information from the various sensory modalities and send it centrally in the nervous system. Presynaptic nerve endings are PRESYNAPTIC TERMINALS. CHEBI:60050 estrone 3-sulfate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60050 UBERON:0012451 sensory receptor biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012451 sensory nerve ending|peripheral ending of sensory neuron A sensory nerve ending that responds to a stimulus in the internal or external environment of an organism. In response to stimuli the sensory receptor initiates sensory transduction by creating graded potentials or action potentials in the same cell or in an adjacent one. CHEBI:60052 siroheme(8-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60052 CHEBI:60051 N-formyl-D-kynurenine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60051 CHEBI:25640 octamethylcyclotetrasiloxane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_25640 CHEBI:60053 cobalt-precorrin-2(8-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60053 CHEBI:60056 cocaine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60056 CHEBI:60055 dermatan 6'-sulfate anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60055 CHEBI:60058 S-acylglutathionate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60058 CHEBI:60057 N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-D-glucosaminyl undecaprenyl diphosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60057 UBERON:0012449 mechanoreceptor biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012449 A sensory receptor that responds to mechanical pressure or distortion. CHEBI:60059 dermatan anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60059 CHEBI:74691 trans-2-icosenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74691 CHEBI:74693 trans-2-tetracosenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74693 CHEBI:74692 trans-2-docosenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74692 CHEBI:11010 (R)-phenyllactoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_11010 CL:0002293 epithelial cell of thymus biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002293 epithelial reticular cell of thymus|thymic epithelial cell|epithelial cell of thymus gland|epithelial reticular cell An epithelial cell of the thymus. Epithelial reticular cells are pleomorphic, stellate, non-phagocytic cells which seem to be supportive in function and are held together by desmosomes. They replace the fibroblastoid reticular cells found in other lymphoid organs. Other epithelial cells in the medulla have the ultrastructure of secretory cells. Although different epithelial cells throughout the thymus appear alike by light microscopy their ultrastructure and function varies. CHEBI:74694 1-palmitoleoyl-sn-glycerol 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74694 CHEBI:74697 1-(9Z)-octadecenoyl-2-(9Z)-hexadecenoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74697 GO:0072056 pyramid development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072056 kidney pyramid development|pyramids development|renal medulla development|renal pyramid development The process whose specific outcome is the progression of the kidney pyramids over time, from its formation to the mature structure. Kidney pyramids are the conical masses that constitute the renal medulla in a multi-lobed mammalian kidney; they contain the loops of Henle and the medullary collecting ducts. GO:0047099 CDP-4-dehydro-6-deoxyglucose reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047099 MetaCyc:1.17.1.1-RXN|EC:1.17.1.1 cytidine diphospho-4-keto-6-deoxy-D-glucose reductase activity|NAD(P)H:CDP-4-keto-6-deoxy-D-glucose oxidoreductase activity|CDP-4-keto-deoxy-glucose reductase activity|CDP-4-dehydro-3,6-dideoxy-D-glucose:NAD(P)+ 3-oxidoreductase activity|CDP-4-keto-6-deoxyglucose reductase activity|CDP-4-keto-6-deoxy-D-glucose-3-dehydrogenase system activity|cytidine diphosphate 4-keto-6-deoxy-D-glucose-3-dehydrogenase activity Catalysis of the reaction: H2O + NAD(P)+ + CDP-4-dehydro-3,6-dideoxy-D-glucose = NAD(P)H + CDP-4-dehydro-6-deoxy-D-glucose. GO:0072055 renal cortex development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072055 The process whose specific outcome is the progression of the renal cortex over time, from its formation to the mature structure. The renal cortex is the outer region of the kidney. GO:0072054 renal outer medulla development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072054 outer renal medulla development The process whose specific outcome is the progression of the renal outer medulla over time, from its formation to the mature structure. The renal outer medulla is the region of the kidney that lies between the renal cortex and the renal inner medulla. GO:0047098 Latia-luciferin monooxygenase (demethylating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047098 RHEA:12677|MetaCyc:1.14.99.21-RXN|EC:1.14.99.21 luciferase (Latia luciferin)|Latia luciferin monooxygenase (demethylating)|Latia-luciferin,hydrogen-donor:oxygen oxidoreductase (demethylating) Catalysis of the reaction: 2 O2 + donor-H2 + Latia luciferin = light + H2O + acceptor + formate + CO2 + oxidized Latia luciferin. GO:0072053 renal inner medulla development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072053 inner renal medulla development The process whose specific outcome is the progression of the renal inner medulla over time, from its formation to the mature structure. The renal inner medulla is unique to mammalian kidneys and is the innermost region of the mammalian kidney. GO:0047097 phylloquinone monooxygenase (2,3-epoxidizing) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047097 RHEA:16745|MetaCyc:1.14.99.20-RXN|KEGG_REACTION:R03510|EC:1.14.99.20 vitamin K 2,3-epoxidase activity|phylloquinone epoxidase activity|vitamin K1 epoxidase activity|phylloquinone,hydrogen-donor:oxygen oxidoreductase (2,3-epoxidizing)|vitamin K epoxidase activity Catalysis of the reaction: AH(2) + O(2) + phylloquinone = 2,3-epoxyphylloquinone + A + H(2)O. GO:0072052 juxtaglomerulus cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072052 The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the kidney as it progresses from its formation to the mature state. GO:0047096 androst-4-ene-3,17-dione monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047096 KEGG_REACTION:R01833|MetaCyc:1.14.99.12-RXN|RHEA:22696|EC:1.14.99.12 androstenedione monooxygenase activity|androst-4-ene-3,17-dione hydroxylase activity|androst-4-ene-3,17-dione 17-oxidoreductase activity|4-androstene-3,17-dione monooxygenase activity|androstene-3,17-dione hydroxylase activity|androst-4-ene-3,17-dione-hydrogen-donor:oxygen oxidoreductase (13-hydroxylating, lactonizing) Catalysis of the reaction: AH(2) + androst-4-ene-3,17-dione + O(2) = A + H(2)O + testololactone. GO:0072051 juxtaglomerular apparatus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072051 The process whose specific outcome is the progression of the juxtaglomerular apparatus over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure that lies adjacent to the glomerulus and regulates kidney function. GO:0047095 2-hydroxycyclohexanone 2-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047095 MetaCyc:1.14.13.66-RXN|RHEA:33283|KEGG_REACTION:R03281|EC:1.14.13.66 2-hydroxycyclohexan-1-one,NADPH:oxygen 2-oxidoreductase (1,2-lactonizing) Catalysis of the reaction: 2-hydroxycyclohexan-1-one + NADPH + O(2) = 6-oxohexanoate + H(2)O + NADP(+). GO:0047094 3-hydroxyphenylacetate 6-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047094 MetaCyc:1.14.13.63-RXN|EC:1.14.13.63 3-hydroxyphenylacetate 6-monooxygenase activity|3-hydroxyphenylacetate,NAD(P)H:oxygen oxidoreductase (6-hydroxylating) Catalysis of the reaction: O2 + NAD(P)H + 3-hydroxyphenylacetate = H2O + NAD(P)+ + homogentisate. GO:0072050 S-shaped body morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072050 The process in which the S-shaped body is generated and organized. The S-shaped body is the successor of the comma-shaped body that contributes to the morphogenesis of the nephron. GO:0047093 4-hydroxyquinoline 3-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047093 MetaCyc:1.14.13.62-RXN|RHEA:19325|KEGG_REACTION:R05154|EC:1.14.13.62 1-H-4-oxoquinoline 3-monooxygenase activity|quinolin-4(1H)-one 3-monooxygenase activity|quinolin-4(1H)-one,NADH:oxygen oxidoreductase (3-oxygenating) Catalysis of the reaction: H(+) + NADH + O(2) + quinolin-4-ol = H(2)O + NAD(+) + quinoline-3,4-diol. DDANAT:0000110 basal region biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000110 base Region of the early pseudoplasmodium located at the closest to the substratum composed of pstB cells. CHEBI:59062 polymyxin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59062 GO:0072059 cortical collecting duct development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072059 The process whose specific outcome is the progression of the cortical collecting duct over time, from its formation to the mature structure. The cortical collecting duct is the portion of the collecting duct that resides in the renal cortex. GO:0072058 outer stripe development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072058 The process whose specific outcome is the progression of the outer stripe over time, from its formation to the mature structure. The outer stripe is the region of the kidney outer medulla that lies just below the cortex. The proximal straight tubules (S3) characterize this region. GO:0072057 inner stripe development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072057 The process whose specific outcome is the progression of the inner stripe over time, from its formation to the mature structure. The inner stripe is a deep, centrally located portion of the renal outer medulla and is traversed by thin descending and thick ascending portions of the loops of Henle. GO:0072045 convergent extension involved in nephron morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072045 The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron. GO:0072044 collecting duct development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072044 The process whose specific outcome is the progression of a collecting duct over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. It is the final common path through which urine flows before entering the ureter and then emptying into the bladder. GO:0072043 regulation of pre-tubular aggregate formation by cell-cell signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072043 regulation of pre-tubular aggregate formation by cell-cell signalling Any process that mediates the transfer of information from one cell to another that modulates the rate, frequency, or extent of pre-tubular aggregate formation. Pre-tubular aggregate formation is the cell adhesion process in which mesenchymal cells adhere to one another in the initial stages of the formation of the pre-tubular aggregate, the earliest recognizable structure of the kidney. GO:0072042 regulation of mesenchymal stem cell proliferation involved in nephron morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072042 Any process that modulates the frequency, rate or extent of mesenchymal stem cell proliferation and contributes to the shaping of a nephron. GO:0072041 positive regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072041 positive regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis|positive regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron. GO:0072040 negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072040 negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis|negative regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron. DDANAT:0000101 prestalk AB core region of the tipped mound biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000101 pstAB region|prestalk AB region of the tipped mound Cone-shaped area of the prestalk zone of the tipped mound that occupies a core among the pstA region. Cells of the pstAB region express both the ecmA and ecmB genes. DDANAT:0000100 prestalk A region of the tipped mound biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000100 pstA region of the tipped mound Anterior-most region of the prestalk zone of the tipped mound characterized by high expression of the ecmA gene directed by the proximal part of its promoter (ecmA promoter). GO:0072049 comma-shaped body morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072049 The process in which the comma-shaped body is generated and organized. The comma-shaped body is the precursor structure to the S-shaped body that contributes to the morphogenesis of the nephron. GO:0072048 renal system pattern specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072048 renal system pattern formation Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate into the anatomical structures of the renal system. GO:0072047 proximal/distal pattern formation involved in nephron development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072047 proximal/distal nephron patterning|proximal-distal pattern formation involved in nephron development The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron. The proximal/distal axis is defined by a line that runs from the center of the kidney (proximal end) outward (distal end). GO:0072046 establishment of planar polarity involved in nephron morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072046 establishment of planar cell polarity involved in nephron morphogenesis Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron. GO:0072078 nephron tubule morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072078 The process in which the anatomical structures of a nephron tubule are generated and organized. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney. GO:0072077 renal vesicle morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072077 The process in which the anatomical structures of the renal vesicle are generated and organized. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells. GO:0072076 nephrogenic mesenchyme development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072076 The biological process whose specific outcome is the progression of a nephrogenic mesenchyme from an initial condition to its mature state. This process begins with the formation of nephrogenic mesenchyme and ends with the mature structure. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron. GO:0072075 metanephric mesenchyme development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072075 The biological process whose specific outcome is the progression of a metanephric mesenchyme from an initial condition to its mature state. This process begins with the formation of metanephric mesenchyme and ends with the mature structure. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros. GO:0072074 kidney mesenchyme development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072074 The biological process whose specific outcome is the progression of a kidney mesenchyme from an initial condition to its mature state. This process begins with the formation of kidney mesenchyme and ends with the mature structure. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney. GO:0072073 kidney epithelium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072073 The process whose specific outcome is the progression of an epithelium in the kidney over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. GO:0072072 kidney stroma development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072072 The process whose specific outcome is the progression of the kidney stroma over time, from its formation to the mature structure. The kidney stroma is the mesenchyme of the mature kidney. GO:0072071 kidney interstitial fibroblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072071 kidney interstitial cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblast of the kidney as it progresses from its formation to the mature state. GO:0072070 loop of Henle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072070 intermediate tubule development The process whose specific outcome is the progression of the loop of Henle over time, from its formation to the mature structure. The loop of Henle is a nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule. CHEBI:132746 N-[(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-icosatetraenoyl]alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132746 CHEBI:132747 N-[(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-icosatetraenoyl]-gamma-aminobutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132747 CHEBI:132749 (S)-nandinine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132749 CHEBI:132740 N-[(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-icosatetraenoyl]-gamma-aminobutanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132740 CHEBI:132742 lysophosphatidic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132742 GO:0072079 nephron tubule formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072079 The developmental process pertaining to the initial formation of a nephron tubule from unspecified parts. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney. GO:0072067 early distal convoluted tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072067 The process whose specific outcome is the progression of the early distal convoluted tubule over time, from its formation to the mature structure. The early distal convoluted tubule contains DCT cells and is vasopressin-insensitive. GO:0072066 prebend segment development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072066 The process whose specific outcome is the progression of the prebend segment over time, from its formation to the mature structure. The prebend segment is a part of the descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability. GO:0072065 long descending thin limb bend development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072065 The process whose specific outcome is the progression of the long descending thin limb bend over time, from its formation to the mature structure. The long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment. GO:0072064 long descending thin limb development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072064 The process whose specific outcome is the progression of the long descending thin limb over time, from its formation to the mature structure. The long descending thin limb is the descending thin limb of a long nephron that has a squamous epithelial morphology. The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla. GO:0072063 short descending thin limb development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072063 The process whose specific outcome is the progression of the short descending thin limb over time, from its formation to the mature structure. The short descending thin limb is the descending thin limb of a short nephron that has a squamous epithelial morphology. GO:0072062 proximal convoluted tubule segment 1 cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072062 S1 cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the S1 cells of the kidney as it progresses from its formation to the mature state. GO:0072061 inner medullary collecting duct development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072061 The process whose specific outcome is the progression of the inner medullary collecting duct over time, from its formation to the mature structure. The inner medullary collecting duct is the portion of the collecting duct that lies in the renal inner medulla. GO:0072060 outer medullary collecting duct development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072060 The process whose specific outcome is the progression of the outer medullary collecting duct over time, from its formation to the mature structure. The outer medullary collecting duct is the portion of the collecting duct that lies in the renal outer medulla. CHEBI:132750 2-methylbutan-2-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132750 CHEBI:132752 3-hydroxy-3-methylbut-1-ene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132752 CHEBI:132755 triethanolammonium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132755 GO:0072069 DCT cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072069 distal convoluted tubule cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the distal convoluted tubule cells of the kidney as it progresses from its formation to the mature state. GO:0072068 late distal convoluted tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072068 The process whose specific outcome is the progression of the late distal convoluted tubule over time, from its formation to the mature structure. The late distal convoluted tubule contains DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive. CHEBI:50699 oligosaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50699 GO:0072099 anterior/posterior pattern specification involved in ureteric bud development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072099 ureteric bud anterior/posterior pattern formation The developmental process that results in the creation of defined areas or spaces within the ureteric bud along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate. GO:0072098 anterior/posterior pattern specification involved in kidney development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072098 anterior/posterior pattern formation involved in kidney development|kidney anterior/posterior pattern formation|kidney anterior/posterior pattern specification The developmental process that results in the creation of defined areas or spaces within the kidney along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate. GO:0072097 negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072097 negative regulation of branch elongation involved in ureteric bud branching by BMP signalling pathway A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor resulting in the reduction of the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis. GO:0072096 negative regulation of branch elongation involved in ureteric bud branching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072096 Any process that reduces the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis. GO:0072095 regulation of branch elongation involved in ureteric bud branching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072095 Any process that modulates the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis. GO:0072094 metanephric renal vesicle induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072094 positive regulation of metanephros formation Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the metanephric renal vesicle. GO:0072093 metanephric renal vesicle formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072093 metanephros formation The developmental process pertaining to the initial formation of the metanephros. GO:0072092 ureteric bud invasion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072092 The process in which the ureteric bud grows along its axis and contributes to the formation of the metanephros. GO:0072091 regulation of stem cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072091 Any process that modulates the frequency, rate or extent of stem cell proliferation. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. GO:0072090 mesenchymal stem cell proliferation involved in nephron morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072090 The multiplication or reproduction of mesenchymal stem cells, resulting in the expansion of a stem cell population, that contributes to the shaping of a nephron. CHEBI:132725 N-[(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-icosatetraenoyl]glycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132725 CHEBI:132727 11a-hydroxytetracycline zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132727 CHEBI:132722 N-arachidonoyl-gamma-aminobutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132722 CHEBI:50691 abortifacient biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50691 CHEBI:50695 monobactam biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50695 CHEBI:50694 minocycline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50694 GO:0072089 stem cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072089 The multiplication or reproduction of stem cells, resulting in the expansion of a stem cell population. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. GO:0072088 nephron epithelium morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072088 The process in which the anatomical structures of the nephron epithelium are generated and organized. The nephron epithelium is a tissue that covers the surface of a nephron. GO:0072087 renal vesicle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072087 The process whose specific outcome is the progression of the renal vesicle over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells. GO:0072086 specification of loop of Henle identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072086 specification of intermediate tubule identity The process in which the loop of Henle of the kidney nephron acquires its identity. GO:0072085 specification of connecting tubule identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072085 The process in which the connecting tubule of the kidney nephron acquires its identity. GO:0072084 specification of distal tubule identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072084 The process in which the distal tubule of the kidney nephron acquires its identity. GO:0072083 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072083 GO:0072082 specification of proximal tubule identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072082 The process in which the proximal tubule of the kidney nephron acquires its identity. CHEBI:50689 reproductive control drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50689 GO:0072081 specification of nephron tubule identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072081 The process in which the tubules arranged along the proximal/distal axis of the nephron acquire their identity. CHEBI:132735 4-hydroxy-6-methylpretetramide(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132735 GO:0072080 nephron tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072080 The progression of a nephron tubule over time, from its initial formation to the mature structure. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney. CHEBI:132734 6-methylpretetramide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132734 CHEBI:132737 4-de(dimethylamino)-4-oxoanhydrotetracycline(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132737 CHEBI:132736 N-[(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-icosatetraenoyl]alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132736 CHEBI:132738 N-[(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-icosatetraenoyl]glycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132738 UBERON:2000940 posterior lateral line neuromast biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_2000940 neuromasts posterior|neuromast posterior Neuromast that is part of the posterior lateral line. Kimmel et al, 1995. (Also see Anatomical Atlas entry for lateral line by T. Whitfield.) CHEBI:50680 methotrexate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50680 CHEBI:35063 alpha-zeacarotene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35063 CHEBI:50684 cross-linking reagent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50684 CHEBI:50683 EC 1.5.1.3 (dihydrofolate reductase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50683 CHEBI:8005 peptidoglycan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_8005 CHEBI:50681 methotrexate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50681 CHEBI:74600 (14Z,17Z,20Z,23Z,26Z,29Z)-dotriacontahexaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74600 CHEBI:50675 beta-D-glucosaminyl-(1->4)-D-glucosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50675 CHEBI:74602 (16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74602 CHEBI:74601 (16Z,19Z,22Z,25Z,28Z,31Z)-3-oxotetratriacontahexaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74601 CHEBI:50674 chitobioses biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50674 CHEBI:74604 guanosine 2'-monophosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74604 CHEBI:74603 (18Z,21Z,24Z,27Z,30Z,33Z)-3-oxohexatriacontahexaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74603 CHEBI:74606 (11Z,14Z,17Z)-icosatrienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74606 CHEBI:74608 (13Z,16Z,19Z)-3-oxodocosatrienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74608 CHEBI:74609 (10Z,13Z,16Z,19Z)-3-oxodocosatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74609 CHEBI:132708 N-arachidonoyl-L-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132708 CHEBI:59002 N-arachidonoylglycinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59002 CHEBI:35032 trioxilin B3 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35032 CHEBI:50671 antithyroid drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50671 CHEBI:74610 (6Z)-hexadecenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74610 CHEBI:74617 1-oleoyl-sn-glycero-3-phosphoserine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74617 CHEBI:50667 mercaptopurine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50667 CHEBI:74619 aclacinomycin A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74619 CHEBI:132717 bleaching agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132717 CHEBI:50661 loliose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50661 CHEBI:50660 7-deazaguanine ribonucleoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50660 GO:0047012 sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047012 MetaCyc:1.1.1.170-RXN|EC:1.1.1.170 3-beta-hydroxy-4-alpha-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating) activity|sterol 4-alpha-carboxylic decarboxylase activity|3-beta-hydroxy-4-beta-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating) activity|3beta-hydroxy-4alpha-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating)|3-beta-hydroxy-4-beta-methylcholestenoate dehydrogenase activity Catalysis of the reaction: NAD(P)+ + 3-beta-hydroxy-4-alpha-methyl-5-alpha-cholest-7-ene-4-beta-carboxylate = NAD(P)H + H+ + CO2 + 4-alpha-methyl-5-alpha-cholest-7-en-3-one. GO:0023045 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0023045 GO:0047011 2-dehydropantolactone reductase (A-specific) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047011 EC:1.1.1.168|MetaCyc:1.1.1.168-RXN (R)-pantolactone:NADP+ oxidoreductase (A-specific)|2-oxopantoyl lactone reductase|ketopantoyl lactone reductase activity|2-dehydropantoyl-lactone reductase (A-specific) activity|2-ketopantoyl lactone reductase activity Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NADP+. GO:0023044 obsolete signaling via chemical mediator biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023044 signalling via chemical mediator|signaling via chemical mediator OBSOLETE. The process in which information is sent from one location to another, within a living organism or between living organisms, via a chemical mediator. GO:0047010 hydroxycyclohexanecarboxylate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047010 MetaCyc:1.1.1.166-RXN|EC:1.1.1.166|RHEA:10516|KEGG_REACTION:R05315 (-)t-3,t-4-dihydroxycyclohexane-c-1-carboxylate-NAD oxidoreductase activity|(1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate:NAD+ 3-oxidoreductase activity|dihydroxycyclohexanecarboxylate dehydrogenase activity Catalysis of the reaction: (1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate + NAD(+) = (1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylate + H(+) + NADH. GO:0023047 obsolete signal initiation by chemical mediator biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023047 signal initiation by chemical mediator OBSOLETE. The process in which a chemical signal causes activation of a receptor. GO:0023046 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0023046 GO:0023049 obsolete signal initiation by protein/peptide mediator biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023049 signal initiation by protein/peptide mediator OBSOLETE. The process in which a protein/peptide signal causes activation of a receptor. GO:0023048 obsolete signal initiation by lipid mediator biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023048 signal initiation by lipid mediator OBSOLETE. The process in which a lipid signal causes activation of a receptor. CL:0002306 epithelial cell of proximal tubule biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002306 kidney proximal tubule epithelial cell An epithelial cell of the proximal tubule of the kidney. GO:0047019 indole-3-acetaldehyde reductase (NADPH) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047019 KEGG_REACTION:R02680|RHEA:17037|MetaCyc:1.1.1.191-RXN|EC:1.1.1.191 (indol-3-yl)ethanol:NADP+ oxidoreductase activity|indoleacetaldehyde (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|indole-3-ethanol:NADP+ oxidoreductase activity Catalysis of the reaction: indole-3-ethanol + NADP(+) = (indol-3-yl)acetaldehyde + H(+) + NADPH. CL:0002305 epithelial cell of distal tubule biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002305 kidney distal tubule epithelial cell An epithelial cell of the distal convoluted tubule of the kidney that helps regulate systemic levels of potassium, sodium, calcium, and pH. GO:0047018 indole-3-acetaldehyde reductase (NADH) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047018 MetaCyc:1.1.1.190-RXN|EC:1.1.1.190|KEGG_REACTION:R02679|RHEA:14873 (indol-3-yl)ethanol:NAD+ oxidoreductase activity|indole-3-ethanol:NAD+ oxidoreductase activity|indoleacetaldehyde reductase activity Catalysis of the reaction: indole-3-ethanol + NAD(+) = (indol-3-yl)acetaldehyde + H(+) + NADH. GO:0047017 prostaglandin-F synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047017 RHEA:10140|MetaCyc:1.1.1.188-RXN|EC:1.1.1.188 PGD2 11-ketoreductase activity|reductase, 15-hydroxy-11-oxoprostaglandin|prostaglandin 11-ketoreductase activity|prostaglandin-D(2) 11-ketoreductase activity|PGF synthetase activity|prostaglandin-D2 11-reductase activity|prostaglandin F synthetase activity|prostaglandin-D2 ketoreductase activity|prostaglandin 11-keto reductase activity|prostaglandin-D2 11-ketoreductase activity|prostaglandin D2-ketoreductase activity|PGD(2) 11-ketoreductase activity|(5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP+ 11-oxidoreductase activity|prostaglandin-F synthetase activity|prostaglandin F synthase activity|PGF2alpha synthetase activity|prostaglandin-D(2) 11-reductase activity|prostaglandin-D(2) ketoreductase activity|NADPH-dependent prostaglandin D2 11-keto reductase activity|synthetase, prostaglandin F2alpha Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-9-alpha,11-alpha,15-trihydroxyprosta-5,13-dienoate = NADPH + H+ + (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate. GO:0047016 cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047016 MetaCyc:1.1.1.181-RXN|EC:1.1.1.181|RHEA:11896 cholest-5-ene-3beta,7alpha-diol:NAD+ 3-oxidoreductase activity|3beta-hydroxy-delta5-C27-steroid oxidoreductase|3-beta-hydroxy-Delta(5)-C(27)-steroid oxidoreductase activity|cholest-5-ene-3beta,7alpha-diol 3beta-dehydrogenase activity Catalysis of the reaction: NAD+ + 7-alpha-hydroxycholesterol = NADH + H+ + 7-alpha-hydroxycholest-4-en-3-one. GO:0023041 neuronal signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023041 The process in which an activated neuronal cell receptor conveys information down a signaling pathway, resulting in a change in the function or state of a cell. This process may be intracellular or intercellular. GO:0047015 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047015 MetaCyc:1.1.1.178-RXN|RHEA:13281|EC:1.1.1.178 2-methyl-3-hydroxybutyryl-CoA dehydrogenase activity|2-methyl-3-hydroxy-butyryl CoA dehydrogenase activity|(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA:NAD+ oxidoreductase activity|2-methyl-3-hydroxybutyryl coenzyme A dehydrogenase activity Catalysis of the reaction: NAD+ + 2-methyl-3-hydroxybutyryl-CoA = NADH + H+ + 2-methylaceto-acetyl-CoA. GO:0023040 obsolete signaling via ionic flux biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023040 signaling via ionic flux|signalling via ionic flux OBSOLETE. The process in which information is sent from one location to another, within a living organism or between living organisms, via ionic flux. GO:0047014 glycerol-3-phosphate 1-dehydrogenase [NADP+] activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047014 RHEA:19773|MetaCyc:1.1.1.177-RXN|EC:1.1.1.177|KEGG_REACTION:R00845 L-glycerol 3-phosphate:NADP oxidoreductase activity|sn-glycerol-3-phosphate:NADP+ 1-oxidoreductase activity|glycerol phosphate (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity|glycerin-3-phosphate dehydrogenase activity|NADPH-dependent glycerin-3-phosphate dehydrogenase activity Catalysis of the reaction: sn-glycerol 3-phosphate + NADP(+) = D-glyceraldehyde 3-phosphate + H(+) + NADPH. GO:0023043 obsolete signaling via lipid mediator biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023043 signaling via lipid mediator|signalling via lipid mediator OBSOLETE. The process in which information is sent from one location to another, within a living organism or between living organisms, via a lipid mediator. GO:0047013 cholate 12-alpha dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047013 MetaCyc:1.1.1.176-RXN|EC:1.1.1.176|RHEA:14129|KEGG_REACTION:R02793 12-alpha-hydroxysteroid dehydrogenase activity|NADP-12alpha-hydroxysteroid dehydrogenase activity|NAD-dependent 12alpha-hydroxysteroid dehydrogenase activity|12alpha-hydroxysteroid:NADP+ 12-oxidoreductase activity|12alpha-hydroxysteroid dehydrogenase activity|12alpha-hydroxy steroid dehydrogenase activity Catalysis of the reaction: cholate + NADP(+) = 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + H(+) + NADPH. GO:0023042 obsolete signaling via protein/peptide mediator biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023042 signaling via protein/peptide mediator|signalling via protein/peptide mediator OBSOLETE. The process in which information is sent from one location to another, within a living organism or between living organisms, via a protein/peptide mediator. GO:0047023 androsterone dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047023 MetaCyc:1.1.1.209-RXN|EC:1.1.1.209 3(17)alpha-hydroxysteroid dehydrogenase activity|3(or 17)alpha-hydroxysteroid:NAD(P)+ oxidoreductase activity|3(or 17)-alpha-hydroxysteroid dehydrogenase activity|3(or 17)alpha-hydroxysteroid dehydrogenase activity Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione. GO:0023034 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0023034 CHEBI:142163 24G7 epitope biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_142163 GO:0023033 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0023033 GO:0047022 7-beta-hydroxysteroid dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047022 Wikipedia:7beta-hydroxysteroid_dehydrogenase_(NADP+)|RHEA:20233|MetaCyc:1.1.1.201-RXN|EC:1.1.1.201 NADP-dependent 7beta-hydroxysteroid dehydrogenase activity|NADP-dependent 7-beta-hydroxysteroid dehydrogenase activity|7beta-hydroxysteroid:NADP+ 7-oxidoreductase activity|7beta-hydroxysteroid dehydrogenase (NADP+) Catalysis of the reaction: NADP+ + a 7-beta-hydroxysteroid = NADPH + H+ + a 7-oxosteroid. GO:0023036 obsolete initiation of signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023036 signal reception|initiation of signal transduction OBSOLETE. The process in which a signal causes activation of a receptor, for example, via a conformation change. GO:0047021 15-hydroxyprostaglandin dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047021 RHEA:11636|KEGG_REACTION:R04552|MetaCyc:1.1.1.197-RXN|EC:1.1.1.197 type II 15-hydroxyprostaglandin dehydrogenase activity|NADP-dependent 15-hydroxyprostaglandin dehydrogenase|NADP-linked 15-hydroxyprostaglandin dehydrogenase|(13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-13-enoate:NADP+ 15-oxidoreductase activity|NADP-specific 15-hydroxyprostaglandin dehydrogenase Catalysis of the reaction: NADP(+) + prostaglandin E(1) = 15-dehydro-prostaglandin E1 + H(+) + NADPH. GO:0047020 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047020 RHEA:20744|MetaCyc:1.1.1.196-RXN|EC:1.1.1.196 15-hydroxy PGD2 dehydrogenase activity|prostaglandin-D 15-dehydrogenase (NADP+) activity|NADP-linked prostaglandin D2 dehydrogenase activity|NADP-dependent 15-hydroxyprostaglandin dehydrogenase|prostaglandin-D 15-dehydrogenase (NADP(+)) activity|prostaglandin-D 15-dehydrogenase (NADP)|15-hydroxyprostaglandin dehydrogenase (NADP)|dehydrogenase, 15-hydroxyprostaglandin (nicotinamide adenine dinucleotide phosphate)|prostaglandin D2 dehydrogenase activity|dehydrogenase, prostaglandin D2|NADP-linked 15-hydroxyprostaglandin dehydrogenase|NADP-PGD2 dehydrogenase activity|NADP-specific 15-hydroxyprostaglandin dehydrogenase|(5Z,13E)-(15S)-9alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate:NADP+ 15-oxidoreductase activity Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate = NADPH + H+ + (5Z,13E)-9-alpha-hydroxy-11,15-dioxoprosta-5,13-dienoate. GO:0023035 CD40 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023035 CD40 signalling pathway A series of molecular signals initiated by the binding of the cell surface receptor CD40 to one of its physiological ligands, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0023038 obsolete signal initiation by diffusible mediator biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023038 signal initiation by diffusible mediator OBSOLETE. The process in which a diffusible signal causes activation of a receptor. GO:0023037 obsolete signal initiation by light biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023037 signal initiation by light OBSOLETE. The process in which a light signal causes activation of a receptor. GO:0023039 obsolete signal initiation by physical damage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023039 signal initiation by physical damage OBSOLETE. The process in which a physical damage signal causes activation of a receptor. CL:0002319 neural cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002319 A cell that is part of the nervous system. GO:0047029 (R)-4-hydroxyphenyllactate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047029 MetaCyc:1.1.1.222-RXN|EC:1.1.1.222 (R)-aromatic lactate dehydrogenase activity|D-hydrogenase, D-aryllactate|(R)-3-(4-hydroxyphenyl)lactate:NAD(P)+ 2-oxidoreductase activity Catalysis of the reaction: NAD(P)+ + (R)-3-(4-hydroxyphenyl)lactate = NAD(P)H + H+ + 3-(4-hydroxyphenyl)pyruvate. GO:0047028 6-pyruvoyltetrahydropterin 2'-reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047028 RHEA:11772|MetaCyc:1.1.1.220-RXN|EC:1.1.1.220 6-pyruvoyl tetrahydropterin (2'-oxo)reductase activity|6-lactoyl-5,6,7,8-tetrahydropterin:NADP+ 2'-oxidoreductase activity|6PPH4(2'-oxo) reductase activity|6-pyruvoyl-tetrahydropterin 2'-reductase activity|6-pyruvoyltetrahydropterin reductase activity|pyruvoyl-tetrahydropterin reductase activity Catalysis of the reaction: NADP+ + 6-lactoyl-5,6,7,8-tetrahydropterin = NADPH + H+ + 6-pyruvoyltetrahydropterin. GO:0023030 MHC class Ib protein binding, via antigen binding groove biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0023030 Interacting selectively and non-covalently with major histocompatibility complex class Ib molecules via the antigen binding groove. GO:0047027 benzyl-2-methyl-hydroxybutyrate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047027 RHEA:16405|MetaCyc:1.1.1.217-RXN|EC:1.1.1.217|KEGG_REACTION:R04370 benzyl 2-methyl-3-hydroxybutyrate dehydrogenase activity|benzyl-(2R,3S)-2-methyl-3-hydroxybutanoate:NADP+ 3-oxidoreductase activity Catalysis of the reaction: benzyl (2R,3S)-2-methyl-3-hydroxybutanoate + NADP(+) = benzyl 2-methyl-3-oxobutanoate + H(+) + NADPH. GO:0047026 androsterone dehydrogenase (A-specific) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047026 MetaCyc:1.1.1.213-RXN|Wikipedia:3alpha-hydroxysteroid_dehydrogenase_(A-specific)|EC:1.1.1.213 3alpha-hydroxysteroid dehydrogenase (A-specific)|3alpha-hydroxysteroid:NAD(P)+ oxidoreductase (A-specific)|3-alpha-hydroxysteroid dehydrogenase (A-specific) activity Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD(P)+. GO:0023032 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0023032 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047025 RHEA:19913|MetaCyc:1.1.1.212-RXN|EC:1.1.1.212 3-oxoacyl-[acyl-carrier protein] reductase (NADH) activity|3-oxoacyl-ACP reductase (NADH) activity|3-oxoacyl-acyl carrier protein (reduced nicotinamide adenine dinucleotide) reductase activity|(3R)-3-hydroxyacyl-acyl-carrier-protein:NAD+ oxidoreductase activity|3-oxoacyl-acyl-carrier-protein reductase (NADH) Catalysis of the reaction: NAD+ + OH-acyl-[acyl-carrier protein] = NADH + H+ + B-ketoacyl-[acyl-carrier protein]. GO:0023031 MHC class Ib protein binding, via lateral surface biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0023031 Interacting selectively and non-covalently with major histocompatibility complex class Ib molecules via the lateral surface. GO:0047024 5alpha-androstane-3beta,17beta-diol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047024 KEGG_REACTION:R04344|MetaCyc:1.1.1.210-RXN|RHEA:16297|EC:1.1.1.210 progesterone reductase activity|3beta(or 20alpha)-hydroxysteroid dehydrogenase activity|3beta(or 20alpha)-hydroxysteroid:NADP+ oxidoreductase activity|3-beta(or 20-alpha)-hydroxysteroid dehydrogenase activity|3-beta-HSD activity|3beta,20alpha-hydroxysteroid oxidoreductase activity|dehydrogenase, 3beta,20alpha-hydroxy steroid Catalysis of the reaction: 5alpha-androstane-3beta,17beta-diol + NADP(+) = 17beta-hydroxy-5alpha-androstan-3-one + H(+) + NADPH. CL:0002313 endocrine-paracrine cell of prostate gland biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002313 glandular cell of prostate|neuro-epithelial cell of prostate gland An ecto-epithelial cell of the prostate gland that secretes hormones. GO:0047034 15-hydroxyicosatetraenoate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047034 EC:1.1.1.232|Reactome:R-HSA-2161789|MetaCyc:1.1.1.232-RXN (15S)-15-hydroxy-5,8,11-cis-13-trans-icosatetraenoate:NAD(P)+ 15-oxidoreductase activity|15-hydroxyeicosatetraenoate dehydrogenase activity Catalysis of the reaction: NAD(P)+ + (15S)-15-hydroxy-5,8,11-cis-13-trans-icosatetraenoate = NAD(P)H + H+ + 15-oxo-5,8,11-cis-13-trans-icosatetraenoate. GO:0023023 MHC protein complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0023023 Interacting selectively and non-covalently with the major histocompatibility complex. GO:0023022 termination of T cell signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023022 The signaling process in which T cell signal transduction is brought to an end rather than being reversibly modulated. GO:0047033 15-hydroxyprostaglandin-I dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047033 EC:1.1.1.231|RHEA:21420|KEGG_REACTION:R03520|MetaCyc:1.1.1.231-RXN PG I2 dehydrogenase activity|prostacyclin dehydrogenase activity|NADP+-dependent PGI2-specific 15-hydroxyprostaglandin dehydrogenase activity|(5Z,13E)-(15S)-6,9alpha-epoxy-11alpha,15-dihydroxyprosta-5,13-dienoate:NADP+ 15-oxidoreductase activity|NADP-linked 15-hydroxyprostaglandin (prostacyclin) dehydrogenase activity Catalysis of the reaction: NADP(+) + prostaglandin I(2) = 15-dehydro-prostaglandin I(2) + H(+) + NADPH. GO:0047032 3-alpha-hydroxyglycyrrhetinate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047032 EC:1.1.1.230|RHEA:20816|KEGG_REACTION:R04099|MetaCyc:1.1.1.230-RXN 3alpha-hydroxyglycyrrhetinate dehydrogenase activity|3alpha-hydroxyglycyrrhetinate:NADP+ 3-oxidoreductase activity Catalysis of the reaction: 3alpha-hydroxyglycyrrhetinate + NADP(+) = 3-oxoglycyrrhetinate + H(+) + NADPH. GO:0023025 MHC class Ib protein complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0023025 Interacting selectively and non-covalently with the class Ib major histocompatibility complex. GO:0047031 diethyl 2-methyl-3-oxosuccinate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047031 RHEA:21008|MetaCyc:1.1.1.229-RXN|KEGG_REACTION:R04387|EC:1.1.1.229 diethyl-(2R,3R)-2-methyl-3-hydroxysuccinate:NADP+ 3-oxidoreductase activity Catalysis of the reaction: diethyl (2R,3R)-2-methyl-3-hydroxysuccinate + NADP(+) = diethyl 2-methyl-3-oxosuccinate + H(+) + NADPH. GO:0023024 MHC class I protein complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0023024 Interacting selectively and non-covalently with the class I major histocompatibility complex. GO:0047030 4-hydroxycyclohexanecarboxylate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047030 KEGG_REACTION:R04307|RHEA:17429|MetaCyc:1.1.1.226-RXN|EC:1.1.1.226 trans-4-hydroxycyclohexanecarboxylate dehydrogenase activity|trans-4-hydroxycyclohexanecarboxylate:NAD+ 4-oxidoreductase activity Catalysis of the reaction: trans-4-hydroxycyclohexanecarboxylate + NAD(+) = 4-oxocyclohexanecarboxylate + H(+) + NADH. GO:0023027 MHC class I protein binding, via antigen binding groove biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0023027 Interacting selectively and non-covalently with major histocompatibility complex class I molecules via the antigen binding groove. GO:0023026 MHC class II protein complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0023026 Interacting selectively and non-covalently with the class II major histocompatibility complex. GO:0023029 MHC class Ib protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0023029 Interacting selectively and non-covalently with major histocompatibility complex class Ib molecules. GO:0023028 MHC class I protein binding, via lateral surface biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0023028 Interacting selectively and non-covalently with major histocompatibility complex class I molecules via the lateral surface. GO:0047039 tetrahydroxynaphthalene reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047039 MetaCyc:1.1.1.252-RXN|EC:1.1.1.252|RHEA:21908 T4HN reductase activity|scytalone:NADP+ delta5-oxidoreductase activity Catalysis of the reaction: NADP+ + scytalone = NADPH + H+ + 1,3,6,8-naphthalenetetrol. GO:0047038 D-arabinitol 2-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047038 MetaCyc:1.1.1.250-RXN|EC:1.1.1.250|RHEA:17389|KEGG_REACTION:R07134 D-arabinitol:NAD+ 2-oxidoreductase (D-ribulose-forming)|D-arabinitol 2-dehydrogenase (ribulose-forming) activity Catalysis of the reaction: D-arabinitol + NAD(+) = D-ribulose + H(+) + NADH. GO:0047037 salutaridine reductase (NADPH) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047037 RHEA:10108|KEGG_REACTION:R04697|MetaCyc:1.1.1.248-RXN|EC:1.1.1.248 salutaridinol:NADP+ 7-oxidoreductase activity Catalysis of the reaction: (7S)-salutaridinol + NADP(+) = H(+) + NADPH + salutaridine. GO:0047036 codeinone reductase (NADPH) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047036 EC:1.1.1.247|RHEA:19209|KEGG_REACTION:R05124|MetaCyc:1.1.1.247-RXN codeine:NADP+ oxidoreductase activity Catalysis of the reaction: codeine + NADP(+) = codeinone + H(+) + NADPH. GO:0023021 termination of signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023021 The signaling process in which signal transduction is brought to an end rather than being reversibly modulated. GO:0047035 testosterone dehydrogenase (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047035 MetaCyc:TESTOSTERONE-17-BETA-DEHYDROGENASE-RXN|RHEA:14929|KEGG_REACTION:R01836|Wikipedia:3alpha(17beta)-hydroxysteroid_dehydrogenase_(NAD+)|MetaCyc:1.1.1.239-RXN|EC:1.1.1.239 17-beta-HSD activity|17beta-hydroxysteroid:NAD+ 17-oxidoreductase activity|17beta-HSD|testosterone 17-beta-dehydrogenase (NAD+) activity|3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity|3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)|testosterone 17b-dehydrogenase activity|3alpha(or 17beta)-hydroxysteroid:NAD+ oxidoreductase activity|testosterone 17beta-dehydrogenase activity|3alpha(17beta)-HSD|3alpha,17beta-hydroxy steroid dehydrogenase activity|17-ketoreductase activity Catalysis of the reaction: testosterone + NAD+ = androst-4-ene-3,17-dione + NADH. GO:0023020 obsolete regulation of gene expression as a consequence of T cell signal transmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023020 regulation of gene expression as a consequence of T cell signal transmission OBSOLETE. Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a T cell signal is released and/or conveyed from one location to another. GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047045 RHEA:14981|Wikipedia:Testosterone_17beta-dehydrogenase_(NADP+)|MetaCyc:1.1.1.64-RXN|KEGG_REACTION:R01838|EC:1.1.1.64 NADP-dependent testosterone-17beta-oxidoreductase activity|17-ketoreductase activity|testosterone 17beta-dehydrogenase (NADP+)|17beta-hydroxysteroid:NADP+ 17-oxidoreductase activity Catalysis of the reaction: NADP+ + testosterone = NADPH + H+ + androst-4-ene-3,17-dione. GO:0023012 obsolete initiation of T cell receptor signaling by binding of a MHC complex to T cell receptor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023012 initiation of T cell receptor signalling by binding of a MHC complex to T cell receptor|initiation of T cell receptor signaling by binding of a MHC complex to T cell receptor OBSOLETE. The process in which binding of an MHC complex to T cell receptor causes activation of T cell receptor signaling. GO:0047044 androstan-3-alpha,17-beta-diol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047044 RHEA:22400|MetaCyc:1.1.1.53-RXN|EC:1.1.1.53 3alpha,20beta-hydroxysteroid:NAD+-oxidoreductase activity|20beta-hydroxysteroid dehydrogenase activity|(R)-20-hydroxysteroid dehydrogenase activity|dehydrogenase, 20beta-hydroxy steroid|3alpha(or 20beta)-hydroxysteroid:NAD+ oxidoreductase activity|cortisone reductase activity|NADH-20beta-hydroxysteroid dehydrogenase activity|3-alpha(or 20-beta)-hydroxysteroid dehydrogenase activity|3alpha(or 20beta)-hydroxysteroid dehydrogenase activity|delta4-3-ketosteroid hydrogenase activity|20beta-HSD Catalysis of the reaction: NAD+ + androstan-3-alpha,17-beta-diol = 17-beta-hydroxyandrostan-3-one + NADH + H+. GO:0023011 obsolete positive regulation of initiation of T cell receptor signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023011 positive regulation of initiation of T cell receptor signaling|positive regulation of initiation of T cell receptor signalling OBSOLETE. Any process that activates, maintains or increases the frequency, rate or extent of the initiation of T cell receptor signaling. GO:0023014 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0023014 GO:0047043 3-alpha-hydroxycholanate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047043 KEGG_REACTION:R04139|RHEA:19585|MetaCyc:1.1.1.52-RXN|EC:1.1.1.52 3alpha-hydroxy-5beta-cholanate:NAD+ oxidoreductase activity|3alpha-hydroxycholanate dehydrogenase activity|alpha-hydroxy-cholanate dehydrogenase activity Catalysis of the reaction: lithocholate + NAD(+) = 3-oxo-5beta-cholanate + H(+) + NADH. GO:0047042 androsterone dehydrogenase (B-specific) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047042 EC:1.1.1.50|Wikipedia:3alpha-hydroxysteroid_dehydrogenase_(B-specific)|MetaCyc:1.1.1.50-RXN 3-alpha-hydroxysteroid dehydrogenase (B-specific) activity|hydroxyprostaglandin dehydrogenase activity|sterognost 3alpha|3alpha-hydroxysteroid oxidoreductase activity|3-alpha-HSD activity|3alpha-hydroxysteroid dehydrogenase (B-specific)|3alpha-hydroxysteroid:NAD(P)+ oxidoreductase (B-specific)|3alpha-HSD Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione. The reaction is B-specific (i.e. the pro-S hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD(P)+. GO:0023013 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0023013 GO:0023016 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0023016 GO:0047041 (S)-carnitine 3-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047041 MetaCyc:1.1.1.254-RXN|EC:1.1.1.254|KEGG_REACTION:R01921|RHEA:11556 D-carnitine dehydrogenase activity|(S)-carnitine:NAD+ oxidoreductase activity Catalysis of the reaction: (S)-carnitine + NAD(+) = 3-dehydrocarnitine + H(+) + NADH. GO:0023015 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0023015 GO:0047040 pteridine reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047040 MetaCyc:1.1.1.253-RXN|KEGG_REACTION:R01812|EC:1.5.1.33|RHEA:19509 ptr1 activity|pteridine reductase 1 activity|PTR1|dihydrobiopterin reduction|5,6,7,8-tetrahydrobiopterin:NADP+ oxidoreductase activity Catalysis of the reaction: 5,6,7,8-tetrahydrobiopterin + 2 NADP(+) = biopterin + 2 H(+) + 2 NADPH. GO:0023018 obsolete T cell activation of signal transmission via diffusible molecule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023018 T cell activation of signal transmission via diffusible molecule OBSOLETE. The process in which signal transmission via a diffusible molecule is initiated by a T cell. GO:0023017 obsolete signal transmission via diffusible molecule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023017 signaling via diffusible mediator|signal transmission via diffusible molecule OBSOLETE. The process in which a signal is conveyed via a diffusible molecule. GO:0047049 (R)-2-hydroxy-fatty acid dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047049 KEGG_REACTION:R03021|MetaCyc:1.1.1.98-RXN|RHEA:15949|EC:1.1.1.98 2-hydroxy fatty acid oxidase|(R)-2-hydroxy-fatty-acid dehydrogenase activity|(R)-2-hydroxystearate:NAD+ oxidoreductase activity|D-2-hydroxy fatty acid dehydrogenase activity Catalysis of the reaction: (R)-2-hydroxystearate + NAD(+) = 2-oxostearate + H(+) + NADH. GO:0047048 3-hydroxybenzyl-alcohol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047048 EC:1.1.1.97|KEGG_REACTION:R04136|RHEA:22340|MetaCyc:1.1.1.97-RXN 3-hydroxybenzyl-alcohol:NADP+ oxidoreductase activity|m-hydroxybenzylalcohol dehydrogenase activity|m-hydroxybenzyl alcohol dehydrogenase activity|m-hydroxybenzyl alcohol (NADP) dehydrogenase activity Catalysis of the reaction: 3-hydroxybenzyl alcohol + NADP(+) = 3-hydroxybenzaldehyde + H(+) + NADPH. GO:0047047 oxaloglycolate reductase (decarboxylating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047047 EC:1.1.1.92|MetaCyc:1.1.1.92-RXN D-glycerate:NAD(P)+ oxidoreductase (carboxylating) Catalysis of the reaction: glycerate + CO2 + NAD(P)+ = NAD(P)H + H+ + 2-hydroxy-3-oxosuccinate. GO:0023010 obsolete regulation of initiation of T cell receptor signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023010 regulation of initiation of T cell receptor signalling|regulation of initiation of T cell receptor signaling OBSOLETE. Any process that modulates the frequency, rate or extent of the initiation of T cell receptor signaling. GO:0047046 homoisocitrate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047046 MetaCyc:1.1.1.87-RXN|EC:1.1.1.87|RHEA:11900 (-)-1-hydroxy-1,2,4-butanetricarboxylate:NAD+ oxidoreductase (decarboxylating)|3-carboxy-2-hydroxyadipate dehydrogenase activity|3-carboxy-2-hydroxyadipate:NAD(+) oxidoreductase (decarboxylating) activity|2-hydroxy-3-carboxyadipate dehydrogenase activity|homoisocitric dehydrogenase activity|3-carboxy-2-hydroxyadipate:NAD+ oxidoreductase (decarboxylating)|(1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate:NAD+ oxidoreductase (decarboxylating)|(-)-1-hydroxy-1,2,4-butanetricarboxylate:NAD(+) oxidoreductase (decarboxylating) activity Catalysis of the reaction: NAD+ + 3-carboxy-2-hydroxyadipate = NADH + H+ + CO2 + 2-keto-adipate. GO:0023019 signal transduction involved in regulation of gene expression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023019 regulation of gene expression as a consequence of signal transmission Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a signal is released and/or conveyed from one location to another. CHEBI:8028 perphenazine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_8028 GO:0072012 glomerulus vasculature development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072012 glomerulus capillary development The biological process whose specific outcome is the progression of a glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the glomerulus vasculature and ends with the mature structure. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus. GO:0047056 (S)-canadine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047056 EC:1.14.19.68|RHEA:21456|KEGG_REACTION:R04400|MetaCyc:1.1.3.36-RXN (S)-tetrahydrocolumbamine,NADPH:oxygen oxidoreductase (methylenedioxy-bridge-forming)|(S)-tetrahydroberberine synthase activity|(S)-tetrahydrocolumbamine oxidase (methylenedioxy-bridge-forming) activity Catalysis of the reaction: (S)-tetrahydrocolumbamine + H(+) + NADPH + O(2) = (S)-canadine + 2 H(2)O + NADP(+). GO:0072011 glomerular endothelium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072011 The process whose specific outcome is the progression of the glomerular endothelium over time, from its formation to the mature structure. The glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus. GO:0047055 salutaridine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047055 EC:1.14.19.67|RHEA:17713|KEGG_REACTION:R04696|MetaCyc:1.1.3.35-RXN (R)-reticuline,NADPH:oxygen oxidoreductase (C-C phenol-coupling)|(R)-reticuline oxidase (C-C phenol-coupling) activity Catalysis of the reaction: (R)-reticuline + H(+) + NADPH + O(2) = 2 H(2)O + NADP(+) + salutaridine. GO:0072010 glomerular epithelium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072010 The process whose specific outcome is the progression of the glomerular epithelium over time, from its formation to the mature structure. The glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus. The glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros. GO:0023003 nuclear migration to the embryo sac center biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023003 nuclear migration to the female gametophyte center|nucleus migration to the female gametophyte centre|nuclear migration to the megagametophyte centre|nuclear migration to the embryo sac centre|nucleus migration to the female gametophyte center|nuclear migration to the megagametophyte center|nuclear migration to the female gametophyte centre Migration of one of the four nuclei at each pole of the eight-nucleate embryo sac, to the center of the cell. GO:0047054 berbamunine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047054 EC:1.14.19.66|RHEA:23576|MetaCyc:1.1.3.34-RXN (S)-N-methylcoclaurine oxidase (C-O phenol-coupling) activity|(S)-N-methylcoclaurine,NADPH:oxygen oxidoreductase (C-O phenol-coupling) Catalysis of the reaction: O2 + NADPH + H+ + R-N-methylcoclaurine + S-N-methylcoclaurine = 2 H2O + NADP+ + berbamunine. GO:0047053 (S)-cheilanthifoline synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047053 MetaCyc:1.14.21.2-RXN|EC:1.14.19.65|KEGG_REACTION:R03834|RHEA:20485 (S)-scoulerine oxidase (methylenedioxy-bridge-forming) activity|(S)-scoulerine,NADPH:oxygen oxidoreductase (methylenedioxy-bridge-forming) Catalysis of the reaction: (S)-scoulerine + H(+) + NADPH + O(2) = (S)-cheilanthifoline + 2 H(2)O + NADP(+). GO:0023002 nuclear migration to embryo sac poles biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023002 nuclear migration to megagametophyte poles|nucleus migration to female gametophyte poles|nucleus migration to megagametophyte poles|nuclear migration to female gametophyte poles|nucleus migration to embryo sac poles Migration of the nuclei of the two-nucleate embryo sac to opposite poles of the cell. CHEBI:8087 N(2)-phenylacetylglutamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_8087 GO:0047052 (S)-stylopine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047052 EC:1.14.19.64|RHEA:13773|KEGG_REACTION:R04690|MetaCyc:1.1.3.32-RXN (S)-cheilanthifoline,NADPH:oxygen oxidoreductase (methylenedioxy-bridge-forming)|(S)-cheilanthifoline oxidase (methylenedioxy-bridge-forming) activity Catalysis of the reaction: (S)-cheilanthifoline + H(+) + NADPH + O(2) = (S)-stylopine + 2 H(2)O + NADP(+). GO:0023005 obsolete signal initiation by neurotransmitter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023005 signal initiation by neurotransmitter OBSOLETE. The process in which a neurotransmitter signal causes activation of a receptor. GO:0023004 obsolete activation of dopamine receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023004 activation of dopamine receptor signalling pathway|activation of dopamine receptor signaling pathway|stimulation of dopamine receptor signaling pathway|initiation of dopamine receptor signaling pathway OBSOLETE. Any process that initiates the dopamine receptor protein signaling pathway through stimulation of the dopamine receptor. GO:0047051 D-lactate dehydrogenase (cytochrome c-553) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047051 MetaCyc:1.1.2.5-RXN|RHEA:16465|EC:1.1.2.5 (R)-lactate:ferricytochrome-c-553 2-oxidoreductase activity Catalysis of the reaction: 2 ferricytochrome C-553 + D-lactate = 2 ferrocytochrome C-553 + pyruvate. GO:0023007 obsolete ligand binding to T cell receptor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023007 ligand binding to T cell receptor OBSOLETE. Binding of a diffusible ligand to a T cell receptor as part of a signaling process. GO:0047050 (S)-2-hydroxy-fatty acid dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047050 EC:1.1.1.99|KEGG_REACTION:R03022|RHEA:11384|MetaCyc:1.1.1.99-RXN L-2-hydroxy fatty acid dehydrogenase activity|2-hydroxy fatty acid oxidase|(S)-2-hydroxy-fatty-acid dehydrogenase activity|dehydrogenase, L-2-hydroxy fatty acid|(S)-2-hydroxystearate:NAD+ oxidoreductase activity Catalysis of the reaction: (S)-2-hydroxystearate + NAD(+) = 2-oxostearate + H(+) + NADH. GO:0023006 obsolete signal initiation by amino acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023006 signal initiation by amino acid OBSOLETE. The process in which an amino acid signal causes activation of a receptor. GO:0047059 polyvinyl alcohol dehydrogenase (cytochrome) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047059 RHEA:20157|KEGG_REACTION:R03136|EC:1.1.2.6|MetaCyc:RXN-11316 polyvinyl alcohol:ferricytochrome-c oxidoreductase activity|polyvinyl-alcohol:(acceptor) oxidoreductase activity|PVA dehydrogenase activity|polyvinyl-alcohol:acceptor oxidoreductase activity Catalysis of the reaction: polyvinyl alcohol + ferricytochrome c = oxidized polyvinyl alcohol + ferrocytochrome c + H+. GO:0047058 vitamin-K-epoxide reductase (warfarin-insensitive) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047058 RHEA:21560|MetaCyc:1.1.4.2-RXN|EC:1.1.4.2 vitamin K 2,3-epoxide reductase activity|3-hydroxy-2-methyl-3-phytyl-2,3-dihydronaphthoquinone:oxidized-dithiothreitol oxidoreductase activity Catalysis of the reaction: 3-hydroxy-2-methyl-3-phytyl-2,3-dihydronaphthoquinone + oxidized dithiothreitol + H2O = 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + 1,4-dithiothreitol. GO:0047057 vitamin-K-epoxide reductase (warfarin-sensitive) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047057 RHEA:13817|Reactome:R-HSA-6806647|MetaCyc:1.1.4.1-RXN|Reactome:R-HSA-159790|EC:1.1.4.1 vitamin K1 epoxide reductase activity|phylloquinone epoxide reductase activity|2-methyl-3-phytyl-1,4-naphthoquinone:oxidized-dithiothreitol oxidoreductase activity Catalysis of the reaction: 2-methyl-3-phytyl-1,4-naphthoquinone + oxidized dithiothreitol + H2O = 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + 1,4-dithiothreitol. GO:0023009 obsolete initiation of T cell receptor signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023009 initiation of T cell receptor signalling|initiation of T cell receptor signaling OBSOLETE. The process in which a signal causes activation of T cell receptor signaling. GO:0072019 proximal convoluted tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072019 The process whose specific outcome is the progression of the proximal convoluted tubule over time, from its formation to the mature structure. The proximal convoluted tubule is the most proximal portion of the proximal tubule and extends from the glomerular capsule to the proximal straight tubule. GO:0072018 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072018 GO:0072017 distal tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072017 The process whose specific outcome is the progression of the distal tubule over time, from its formation to the mature structure. In mammals, the distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule. GO:0072016 glomerular parietal epithelial cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072016 Bowman's capsule development The process whose specific outcome is the progression of a glomerular parietal epithelial cell over time, from its formation to the mature structure. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. GO:0072015 glomerular visceral epithelial cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072015 podocyte development The process whose specific outcome is the progression of a glomerular visceral epithelial cell over time, from its formation to the mature structure. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells. GO:0072014 proximal tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072014 The process whose specific outcome is the progression of the proximal tubule over time, from its formation to the mature structure. In mammals, the proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology. GO:0072013 glomus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072013 pronephric glomus development The progression of the glomus over time from its initial formation until its mature state. The glomus forms from the splanchnic intermediate mesoderm and is the vascularized filtration unit, filtering the blood before it enters the tubules. The glomus is external to the nephron and extends over more than one body segment. GO:0047067 hydrogen:quinone oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047067 RHEA:18641|EC:1.12.5.1|MetaCyc:1.12.5.1-RXN|KEGG_REACTION:R02965 membrane-bound hydrogenase activity|hydrogen:menaquinone oxidoreductase activity|quinone-reactive Ni/Fe-hydrogenase activity|hydrogen-ubiquinone oxidoreductase activity Catalysis of the reaction: H(2) + menaquinone = reduced menaquinone. GO:0072001 renal system development biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0072001 urinary system development|urinary tract development The process whose specific outcome is the progression of the renal system over time, from its formation to the mature structure. The renal system maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels. GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047066 Reactome:R-HSA-9018868|RHEA:19057|Reactome:R-HSA-9018895|Reactome:R-HSA-9020271|Reactome:R-HSA-9020273|MetaCyc:1.11.1.12-RXN|EC:1.11.1.12 peroxidation-inhibiting protein: peroxidase, glutathione (phospholipid hydroperoxide-reducing)|phospholipid hydroperoxide glutathione peroxidase activity|glutathione:lipid-hydroperoxide oxidoreductase activity|hydroperoxide glutathione peroxidase activity|peroxidation-inhibiting protein activity|PHGPX Catalysis of the reaction: a lipid hydroperoxide + 2 reduced glutathione = 2 H2O + lipid + 2 oxidized glutathione. GO:0072000 extracellular polysaccharide catabolic process involved in ascospore release from ascus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072000 ascus catabolic process|ascus endolysis|extracellular polysaccharide breakdown involved in ascospore release from ascus|extracellular polysaccharide degradation involved in ascospore release from ascus|extracellular polysaccharide catabolism involved in ascospore release from ascus The chemical reactions and pathways resulting in the breakdown of polysaccharides in the ascus wall that contributes to the release of ascospores from the ascus. GO:0047065 sulochrin oxidase [(-)-bisdechlorogeodin-forming] activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047065 KEGG_REACTION:R00061|EC:1.21.3.5|MetaCyc:1.10.3.8-RXN|RHEA:22616 sulochrin:oxygen oxidoreductase (cyclizing, (-)-specific)|sulochrin oxidase activity Catalysis of the reaction: O(2) + 2 sulochrin = 2 (2R)-bisdechlorogeodin + 2 H(2)O. GO:0047064 sulochrin oxidase [(+)-bisdechlorogeodin-forming] activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047064 KEGG_REACTION:R00060|EC:1.21.3.4|RHEA:24092|MetaCyc:1.10.3.7-RXN sulochrin:oxygen oxidoreductase (cyclizing, (+)-specific)|sulochrin oxidase activity Catalysis of the reaction: O(2) + 2 sulochrin = 2 (2S)-bisdechlorogeodin + 2 H(2)O. GO:0047063 obsolete L-ascorbate-cytochrome-b5 reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047063 RHEA:18677|EC:1.10.2.1|MetaCyc:1.10.2.1-RXN L-ascorbate:ferricytochrome-b5 oxidoreductase activity|ascorbate-cytochrome b5 reductase activity OBSOLETE. Catalysis of the reaction: ferricytochrome B5 + ascorbate = ferrocytochrome B5 + monodehydroascorbate. GO:0047062 trans-acenaphthene-1,2-diol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047062 KEGG_REACTION:R04059|RHEA:22184|EC:1.10.1.1|MetaCyc:1.10.1.1-RXN trans-1,2-acenaphthenediol dehydrogenase activity|(+-)-trans-acenaphthene-1,2-diol:NADP+ oxidoreductase activity Catalysis of the reaction: (+-)-trans-acenaphthene-1,2-diol + 2 NADP(+) = acenaphthene-1,2-dione + 2 H(+) + 2 NADPH. GO:0047061 glucose-fructose oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047061 MetaCyc:1.1.99.28-RXN|EC:1.1.99.28|RHEA:20637|KEGG_REACTION:R00874 D-glucose:D-fructose oxidoreductase activity Catalysis of the reaction: D-fructose + D-glucose = D-glucitol + D-glucono-1,5-lactone. GO:0047060 (R)-pantolactone dehydrogenase (flavin) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047060 KEGG_REACTION:R03156|MetaCyc:1.1.99.27-RXN|EC:1.1.99.27|RHEA:21004 (R)-pantolactone:acceptor oxidoreductase (flavin-containing)|2-dehydropantoyl-lactone reductase (flavin) activity|2-dehydropantolactone reductase (flavin) activity|(R)-pantoyllactone dehydrogenase (flavin) activity Catalysis of the reaction: (R)-pantolactone + A = 2-dehydropantolactone + AH(2). GO:0047069 7,8-dihydroxykynurenate 8,8a-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047069 MetaCyc:1.13.11.10-RXN|RHEA:23400|KEGG_REACTION:R03253|EC:1.13.11.10 7,8-dihydroxykynurenate:oxygen 8,8alpha-oxidoreductase (decyclizing)|7,8-dihydroxykynurenate:oxygen 8,8a-oxidoreductase (decyclizing)|7,8-dihydroxykynurenate oxygenase activity|7,8-dihydroxykynurenate 8,8alpha-dioxygenase activity Catalysis of the reaction: 7,8-dihydroxykynurenate + O(2) = 5-(3-carboxylato-3-oxoprop-1-en-1-yl)-4,6-dihydroxypyridine-2-carboxylate + H(+). GO:0047068 N5,N10-methenyltetrahydromethanopterin hydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047068 KEGG_REACTION:R04455|MetaCyc:H2-METHYLENE-THMPT-DEHYDRO-RXN|EC:1.12.98.2|RHEA:20017 hydrogen:N5,N10-methenyltetrahydromethanopterin oxidoreductase activity|N5,N10-methylenetetrahydromethanopterin dehydrogenase activity|N(5),N(10)-methenyltetrahydromethanopterin hydrogenase activity|5,10-methenyltetrahydromethanopterin hydrogenase activity|H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase activity|H2-dependent methylene-H4MPT dehydrogenase activity|H(2)-forming N(5),N(10)-methylenetetrahydromethanopterin dehydrogenase activity|H(2)-dependent methylene-H(4)MPT dehydrogenase activity|hydrogen:5,10-methenyltetrahydromethanopterin oxidoreductase activity|nonmetal hydrogenase activity|hydrogen:N(5),N(10)-methenyltetrahydromethanopterin oxidoreductase activity Catalysis of the reaction: 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H(2) = 5,10-methylenetetrahydromethanopterin + H(+). GO:0072009 nephron epithelium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072009 The process whose specific outcome is the progression of the nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The nephron epithelium is a tissue that covers the surface of a nephron. GO:0047070 3-carboxyethylcatechol 2,3-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047070 MetaCyc:1.13.11.16-RXN|RHEA:23840|EC:1.13.11.16 3-(2,3-dihydroxyphenyl)propanoate:oxygen 1,2-oxidoreductase activity|2,3-dihydroxy-beta-phenylpropionic dioxygenase activity|2,3-dihydroxy-beta-phenylpropionate oxygenase activity|3-(2,3-dihydroxyphenyl)propanoate:oxygen 1,2-oxidoreductase (decyclizing) Catalysis of the reaction: O2 + 3-(2,3-dihydroxyphenyl)propanoate = 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate. GO:0072008 glomerular mesangial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072008 The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the kidney as it progresses from its formation to the mature state. GO:0072007 mesangial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072007 The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the kidney as it progresses from its formation to the mature state. GO:0072006 nephron development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072006 nephrogenesis The process whose specific outcome is the progression of the nephron over time, from its formation to the mature structure. A nephron is the functional unit of the kidney. GO:0072005 maintenance of kidney identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072005 maintenance of kidney anlage identity The process in which the identity of a kidney is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized. GO:0072004 kidney field specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072004 specification of kidney anlage The process that results in the delineation of regions of the embryo into the area in which the kidney rudiment will develop. GO:0072003 kidney rudiment formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072003 kidney anlage formation The developmental process pertaining to the initial formation of a kidney rudiment from unspecified parts. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. GO:0072002 Malpighian tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072002 The process whose specific outcome is the progression of the Malpighian tubule over time, from its formation to the mature structure. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut. GO:0047078 3-hydroxy-4-oxoquinoline 2,4-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047078 RHEA:17949|MetaCyc:1.13.11.47-RXN|EC:1.13.11.47 quinoline-3,4-diol 2,4-dioxygenase activity|1H-3-hydroxy-4-oxoquinoline 2,4-dioxygenase activity|3-hydroxy-4(1H)-one, 2,4-dioxygenase activity|3-hydroxy-1H-quinolin-4-one 2,4-dioxygenase (CO-forming)|3-hydroxy-4-oxo-1,4-dihydroquinoline 2,4-dioxygenase activity|(1H)-3-hydroxy-4-oxoquinoline 2,4-dioxygenase activity Catalysis of the reaction: O2 + 3-hydroxy-1H-quinolin-4-one = carbon monoxide + N-formylanthranilate. GO:0072034 renal vesicle induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072034 nephron induction|positive regulation of nephron formation Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the renal vesicle. GO:0072033 renal vesicle formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072033 nephron epithelium formation The developmental process pertaining to the initial formation of the renal vesicle from condensed mesenchymal cells. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells. GO:0047077 Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047077 RHEA:10732|MetaCyc:1.13.12.7-RXN|EC:1.13.12.7 Photinus-luciferin 4-monooxygenase (ATP-hydrolysing)|firefly luciferin luciferase activity|Photinus luciferin 4-monooxygenase (adenosine triphosphate-hydrolyzing)|Photinus pyralis luciferase activity|firefly luciferase activity|luciferase activity|luciferase (firefly luciferin)|Photinus-luciferin:oxygen 4-oxidoreductase (decarboxylating, ATP-hydrolysing) Catalysis of the reaction: O2 + ATP + Photinus luciferin = light + diphosphate + AMP + CO2 + oxidized Photinus luciferin. GO:0072032 proximal convoluted tubule segment 2 development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072032 S2 development The process whose specific outcome is the progression of the S2 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S2 portion of the tubule is involved in reabsorption of water and sodium chloride. GO:0047076 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0047076 GO:0072031 proximal convoluted tubule segment 1 development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072031 S1 development The process whose specific outcome is the progression of the S1 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the proximal convoluted tubule and is responsible for avid reabsorption of water and solutes. GO:0047075 2,5-dihydroxypyridine 5,6-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047075 UM-BBD_reactionID:r1443|RHEA:27522|MetaCyc:1.13.11.9-RXN|EC:1.13.11.9 2,5-dihydroxypyridine oxygenase activity|pyridine-2,5-diol dioxygenase activity|2,5-dihydroxypyridine:oxygen 5,6-oxidoreductase activity Catalysis of the reaction: H2O + O2 + 2,5-dihydroxypyridine = formate + maleamate. GO:0072030 short nephron development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072030 The process whose specific outcome is the progression of a short nephron over time, from its formation to the mature structure. Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb. GO:0047074 4-hydroxycatechol 1,2-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047074 EC:1.13.11.-|RHEA:35595|MetaCyc:RXN-10137 Catalysis of the reaction: O2 + benzene-1,2,4-triol = maleylacetate. GO:0047073 2,4'-dihydroxyacetophenone dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047073 EC:1.13.11.41|KEGG_REACTION:R01305|RHEA:24416|UM-BBD_reactionID:r1410|MetaCyc:1.13.11.41-RXN (4-hydroxybenzoyl)methanol oxygenase activity|2,4'-dihydroxyacetophenone oxidoreductase (C-C-bond-cleaving) Catalysis of the reaction: 2,4'-dihydroxyacetophenone + O(2) = 4-hydroxybenzoate + formate + 2 H(+). GO:0047072 2,3-dihydroxybenzoate 2,3-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047072 KEGG_REACTION:R01506|MetaCyc:1.13.11.28-RXN|RHEA:15369|EC:1.13.11.28 2,3-dihydroxybenzoate 2,3-oxygenase activity|2,3-dihydroxybenzoate:oxygen 2,3-oxidoreductase (decyclizing) Catalysis of the reaction: 2,3-dihydroxybenzoate + O(2) = 2-carboxy-cis,cis-muconate + 2 H(+). GO:0047071 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047071 MetaCyc:1.13.11.25-RXN|KEGG_REACTION:R04597|RHEA:21352|UM-BBD_reactionID:r1151|EC:1.13.11.25 steroid 4,5-dioxygenase activity|3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione:oxygen 4,5-oxidoreductase (decyclizing)|3-alkylcatechol 2,3-dioxygenase activity Catalysis of the reaction: 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + O(2) = 3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate + H(+). CHEBI:142110 8-methylmenaquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142110 GO:0047079 deoxyuridine 1'-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047079 EC:1.14.11.10|RHEA:23316|MetaCyc:1.14.11.10-RXN|KEGG_REACTION:R02486 pyrimidine-deoxynucleoside,2-oxoglutarate 1'-dioxygenase activity|2'-deoxyuridine,2-oxoglutarate:oxygen oxidoreductase (1'-hydroxylating)|pyrimidine-deoxynucleoside 1'-dioxygenase activity Catalysis of the reaction: 2'-deoxyuridine + 2-oxoglutarate + O(2) = 2-deoxy-D-ribono-1,4-lactone + CO(2) + succinate + uracil. GO:0047081 3-hydroxy-2-methylpyridinecarboxylate dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047081 MetaCyc:1.14.12.4-RXN|EC:1.14.13.242|RHEA:10864 methylhydroxypyridine carboxylate dioxygenase activity|methylhydroxypyridinecarboxylate oxidase activity|3-hydroxy-2-methylpyridine-5-carboxylate,NADPH:oxygen oxidoreductase (decyclizing)|3-hydroxy-3-methylpyridinecarboxylate dioxygenase activity|2-methyl-3-hydroxypyridine 5-carboxylic acid dioxygenase activity Catalysis of the reaction: O2 + NADPH + H+ + 3-hydroxy-2-methylpyridine-5-carboxylate = NADP+ + 2-(acetamidomethylene)succinate. GO:0047080 deoxyuridine 2'-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047080 MetaCyc:1.14.11.3-RXN|EC:1.14.11.3|KEGG_REACTION:R01879|RHEA:21076 thymidine 2'-hydroxylase activity|thymidine 2-oxoglutarate dioxygenase activity|deoxyuridine 2'-hydroxylase activity|pyrimidine-deoxynucleoside,2-oxoglutarate 2'-dioxygenase activity|pyrimidine deoxyribonucleoside 2'-hydroxylase activity|thymidine dioxygenase activity|thymidine 2'-dioxygenase activity|2'-deoxyuridine,2-oxoglutarate:oxygen oxidoreductase (2'-hydroxylating)|pyrimidine-deoxynucleoside 2'-dioxygenase activity Catalysis of the reaction: 2'-deoxyuridine + 2-oxoglutarate + O(2) = CO(2) + succinate + uridine. GO:0072039 regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072039 regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis|regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron. GO:0072038 mesenchymal stem cell maintenance involved in nephron morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072038 The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells. GO:0072037 mesenchymal stem cell differentiation involved in nephron morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072037 The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephron. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells. GO:0072036 mesenchymal to epithelial transition involved in renal vesicle formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072036 A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the renal vesicle. GO:0072035 pre-tubular aggregate formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072035 mesenchymal cell condensation involved in renal vesicle formation|nephron epithelium formation The cell adhesion process in which mesenchyme cells adhere to one another in the initial stages of the formation of the pre-tubular aggregate, the earliest recognizable structure of the kidney. GO:0072023 thick ascending limb development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072023 TAL development The process whose specific outcome is the progression of the thick ascending limb over time, from its formation to the mature structure. The thick ascending limb is the last part of the loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. At the macula densa, the thick ascending limb connects to the distal convoluted tubule. GO:0047089 dihydrochelirubine 12-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047089 EC:1.14.14.101|KEGG_REACTION:R04708|MetaCyc:1.14.13.57-RXN|RHEA:10156 dihydrochelirubine,NADPH:oxygen oxidoreductase (12-hydroxylating)|dihydrochelirubine 12-hydroxylase activity Catalysis of the reaction: dihydrochelirubine + H(+) + NADPH + O(2) = 12-hydroxydihydrochelirubine + H(2)O + NADP(+). GO:0047088 dihydrosanguinarine 10-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047088 EC:1.14.14.100|RHEA:10528|KEGG_REACTION:R04702|MetaCyc:1.14.13.56-RXN dihydrosanguinarine,NADPH:oxygen oxidoreductase (10-hydroxylating)|dihydrosanguinarine 10-hydroxylase activity Catalysis of the reaction: dihydrosanguinarine + H(+) + NADPH + O(2) = 10-hydroxydihydrosanguinarine + H(2)O + NADP(+). GO:0072022 descending thin limb development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072022 The process whose specific outcome is the progression of the descending thin limb over time, from its formation to the mature structure. The descending thin limb is a part of the loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the loop of Henle. GO:0072021 ascending thin limb development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072021 The process whose specific outcome is the progression of an ascending thin limb over time, from its formation to the mature structure. The ascending thin limb is a segment of a nephron tubule lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent. GO:0047087 protopine 6-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047087 EC:1.14.14.98|RHEA:22644|KEGG_REACTION:R04699|MetaCyc:1.14.13.55-RXN protopine,NADPH:oxygen oxidoreductase (6-hydroxylating)|protopine 6-hydroxylase activity Catalysis of the reaction: H(+) + NADPH + O(2) + protopine = 6-hydroxyprotopine + H(2)O + NADP(+). GO:0047086 ketosteroid monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047086 EC:1.14.13.54|MetaCyc:1.14.13.54-RXN androstenedione, NADPH2:oxygen oxidoreductase (17-hydroxylating, lactonizing)|ketosteroid,NADPH:oxygen oxidoreductase (20-hydroxylating, ester-producing/20-hydroxylating, side-chain cleaving/17-hydroxylating, lactonizing)|progesterone, NADPH2:oxygen oxidoreductase (20-hydroxylating, ester-producing)|17alpha-hydroxyprogesterone, NADPH2:oxygen oxidoreductase (20-hydroxylating, side-chain cleaving)|steroid-ketone monooxygenase activity Catalysis of the reaction: O2 + NADPH + progesterone = H2O + NADP+ + testosterone acetate. GO:0072020 proximal straight tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072020 S3 development The process whose specific outcome is the progression of the proximal straight tubule over time, from its formation to the mature structure. The proximal straight tubule is the part of the descending limb that extends from the proximal convoluted tubule to the descending thin tubule. GO:0047085 hydroxyphenylacetonitrile 2-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047085 KEGG_REACTION:R02708|RHEA:23740|MetaCyc:1.14.13.42-RXN 4-hydroxyphenylacetonitrile monooxygenase activity|4-hydroxyphenylacetonitrile,NADPH:oxygen oxidoreductase (2-hydroxylating)|4-hydroxyphenylacetonitrile hydroxylase activity Catalysis of the reaction: 4-hydroxyphenylacetonitrile + H(+) + NADPH + O(2) = 4-hydroxymandelonitrile + H(2)O + NADP(+). GO:0047084 methyltetrahydroprotoberberine 14-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047084 EC:1.14.14.97|MetaCyc:1.14.13.37-RXN|RHEA:23684 (S)-N-methylcanadine,NADPH:oxygen oxidoreductase (14-hydroxylating)|methyltetrahydroprotoberberine 14-hydroxylase activity|(S)-cis-N-methyltetrahydroberberine 14-monooxygenase activity|(S)-cis-N-methyltetrahydroprotoberberine-14-hydroxylase activity Catalysis of the reaction: O2 + NADPH + H+ + (S)-N-methylcanadine = H2O + NADP+ + allocryptopine. CHEBI:8075 phenoxyacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_8075 GO:0047083 5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047083 RHEA:16265|EC:1.14.14.96|MetaCyc:1.14.13.36-RXN coumaroylquinate(coumaroylshikimate) 3'-monooxygenase activity|trans-5-O-(4-coumaroyl)-D-quinate,NADPH:oxygen oxidoreductase (3'-hydroxylating)|5-O-(4-coumaroyl)-D-quinate/shikimate 3'-hydroxylase activity Catalysis of the reaction: O2 + NADPH + H+ + trans-5-O-(4-coumaroyl)-D-quinate = H2O + NADP+ + trans-5-O-caffeoyl-D-quinate. GO:0047082 3,9-dihydroxypterocarpan 6a-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047082 RHEA:15321|MetaCyc:RXN-4505|EC:1.14.14.93|KEGG_REACTION:R03452 3,9-dihydroxypterocarpan 6a-hydroxylase activity|3,9-dihydroxypterocarpan 6alpha-monooxygenase|(6aR,11aR)-3,9-dihydroxypterocarpan,NADPH:oxygen oxidoreductase (6a-hydroxylating) Catalysis of the reaction: (6aR,11aR)-3,9-dihydroxypterocarpan + H(+) + NADPH + O(2) = (6aS,11aS)-3,6a,9-trihydroxypterocarpan + H(2)O + NADP(+). (6aS,11aS)-3,6a,9-trihydroxypterocarpan is also known as (-)-glycinol. CHEBI:132797 8-oxoresolvin D1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132797 CHEBI:142106 5,6-dihydrouridine 5'-monophosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142106 GO:0047092 27-hydroxycholesterol 7-alpha-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047092 RHEA:24308|MetaCyc:1.14.13.60-RXN|EC:1.14.14.29 27-hydroxycholesterol 7alpha-hydroxylase activity|27-hydroxycholesterol 7-alpha-hydroxylase activity|27-hydroxycholesterol 7a-hydroxylase activity|27-hydroxycholesterol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating)|27-hydroxycholesterol 7alpha-monooxygenase activity Catalysis of the reaction: O2 + NADPH + 27-hydroxycholesterol = H2O + NADP+ + 7-alpha,27-dihydroxycholesterol. GO:0047091 L-lysine 6-monooxygenase (NADPH) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047091 KEGG_REACTION:R00448|MetaCyc:1.14.13.59-RXN|RHEA:23228|EC:1.14.13.59 L-lysine,NADPH:oxygen oxidoreductase (6-hydroxylating)|lysine N(6)-hydroxylase activity|L-lysine 6-monooxygenase activity|lysine N6-hydroxylase activity Catalysis of the reaction: L-lysine + NADPH + O(2) = N(6)-hydroxy-L-lysine + H(2)O + NADP(+). GO:0047090 benzoyl-CoA 3-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047090 KEGG_REACTION:R02449|MetaCyc:1.14.13.58-RXN|RHEA:23216|EC:1.14.13.58 benzoyl-CoA,NADPH:oxygen oxidoreductase (3-hydroxylating)|benzoyl-CoA 3-hydroxylase activity Catalysis of the reaction: benzoyl-CoA + H(+) + NADPH + O(2) = 3-hydroxybenzoyl-CoA + H(2)O + NADP(+). GO:0072029 long nephron development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072029 juxtamedullary nephron development The process whose specific outcome is the progression of a long nephron over time, from its formation to the mature structure. Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla. GO:0072028 nephron morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072028 The process in which the anatomical structures of the nephron are generated and organized. A nephron is the functional unit of the kidney. GO:0072027 connecting tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072027 connecting duct development The process whose specific outcome is the progression of the connecting tubule over time, from its formation to the mature structure. The connecting tubule is a tubular segment of the nephron; it connects the distal convoluted tubule to the collecting duct. GO:0072026 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072026 GO:0072025 distal convoluted tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072025 The process whose specific outcome is the progression of the distal convoluted tubule over time, from its formation to the mature structure. The distal convoluted tubule is the first segment of the nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter. GO:0072024 macula densa development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072024 The process whose specific outcome is the progression of the macula densa over time, from its formation to the mature structure. The macula densa is an area of specialized cells in the distal tubule that makes contact with the vascular pole of the glomerulus. CHEBI:74589 Ser-tRNA(Sec) polyanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74589 GO:0106034 protein maturation by [2Fe-2S] cluster transfer biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106034 The transfer of an assembled [2Fe-2S] cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein. GO:0106033 spine synapse biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0106033 dendritic spine synapse A type of synapse occurring between an axon and a dendritic spine. CHEBI:74588 (10Z,13Z,16Z,19Z,22Z,25Z)-3-oxooctacosahexaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74588 GO:0106032 snRNA pseudouridine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106032 Catalysis of the reaction: an snRNA uridine = an snRNA pseudouridine. Conversion of uridine in an snRNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5. GO:0106038 obsolete vesicle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106038 vesicle biosynthesis|vesicle formation OBSOLETE. A process carried out at the cellular level, which results in the arrangement of constituent parts of a vesicle. Vesicle assembly begins with membrane bending (GO:0097753) and ends with fusion of the vesicle after vesicle scission (GO:0099050). GO:0106037 apicomedial cortex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0106037 medioapical cortex The region that lies just beneath the plasma membrane in the middle of the apical edge of a cell. CHEBI:25614 nylons biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25614 GO:0106036 assembly of apicomedial cortex actomyosin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106036 A process which results in the assembly or arrangement of constituent parts apicomedial cortex actomyosin. CHEBI:25613 nucleotidyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25613 GO:0106035 protein maturation by [4Fe-4S] cluster transfer biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106035 The transfer of an assembled 4Fe-4S] cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein. GO:0106039 obsolete vesicle fusion involved in vesicle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106039 OBSOLETE. A process carried out at the cellular level, which is the final step in vesicle assembly. Vesicle fusion occurs when a newly assembled vesicle closes up, following vesicle vesicle scission (GO:0099050). CL:0002385 blastoconidium biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002385 blastospore An oblong or round asexual spore formed from conidial chains. CL:0002387 arthroconidium biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002387 arthrospore Cylindrical spore formed by development and compartmentation of hyphae; the hyphae are often supporting blastoconidiophores. CHEBI:74581 gamma-linolenoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74581 CHEBI:74583 1-icosanoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74583 CHEBI:74582 1-(gamma-linolenoyl)-2-oleoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74582 GO:0106041 positive regulation of GABA-A receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106041 Any process that activates or increases the frequency, rate or extent of GABA-A receptor activity. CHEBI:74585 (8Z,11Z,14Z,17Z,20Z,23Z)-3-oxohexacosahexaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74585 GO:0106040 regulation of GABA-A receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106040 Any process that modulates the frequency, rate or extent of GABA-A receptor activity. CHEBI:74584 1-icosanoyl-2-oleoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74584 CHEBI:74587 (8Z,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74587 CHEBI:74586 1-myristoyl-2-oleoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74586 GO:0106045 guanine deglycation, methylglyoxal removal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106045 The removal of methylglyoxal from a glycated guanine, to form lactate and a deglycated guanine. CHEBI:25622 orthoquinones biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25622 GO:0106044 guanine deglycation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106044 The removal of a sugar or dicarbonyl from a glycated guanine. GO:0106042 negative regulation of GABA-A receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106042 Any process that stops, prevents or reduces the frequency, rate or extent of GABA-A receptor activity. CHEBI:25626 octadecadienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_25626 GO:0106049 regulation of cellular response to osmotic stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106049 Any process that modulates the frequency, rate or extent of the cellular response to osmotic stress. GO:0106048 spermidine deacetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106048 N8-acetylspermidine deacetylation The modification of acetylspermadine by the removal of acetyl groups. GO:0106047 polyamine deacetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106047 The modification of acetylpolyamine by the removal of acetyl groups. GO:0106046 guanine deglycation, glyoxal removal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106046 The removal of glyoxal from a glycated guanine, to form glycolate and a deglycated guanine. CL:0002397 CD14-positive, CD16-positive monocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002397 CD16+ monocyte A CD14-positive monocyte that is also CD16-positive and CCR2-negative. CL:0002396 CD14-low, CD16-positive monocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002396 non-classical monocyte, human A patrolling monocyte that is CD14-low and CD16-positive. CL:0002398 Gr1-positive, CD43-positive monocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002398 An intermediate monocyte that is Gr1-positive, CD43-positive. CHEBI:74590 (10Z,13Z,16Z,19Z,22Z,25Z)-octacosahexaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74590 CHEBI:74592 (12Z,15Z,18Z,21Z,24Z,27Z)-3-oxotriacontahexaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74592 CHEBI:25629 octadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_25629 CHEBI:25627 octadecadienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25627 CHEBI:74593 (12Z,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74593 CL:0002393 intermediate monocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002393 A monocyte that has characteristics of both patrolling and inflammatory monocytes. CHEBI:74596 Ins-1-P-Cer-C(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74596 CHEBI:74595 (14Z,17Z,20Z,23Z,26Z,29Z)-3-oxodotriacontahexaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74595 GO:0106050 tRNA 2'-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106050 Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing a 2'-O-nucleotide. CL:0002395 Gr1-high classical monocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002395 A resident monocyte that is Gr-1 high, CD43-negative, CX3CR1-negative, CD115-positive, and B220-negative. CHEBI:74597 Ins-1-P-Cer-C biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74597 GO:0106056 regulation of calcineurin-mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106056 Any process that modulates the frequency, rate or extent of calcineurin-mediated signaling. GO:0106055 mannosyl-oligosaccharide 1,2-alpha-mannosidase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0106055 IntAct:EBI-16411902 A protein complex capable of catalysing the hydrolysis of the terminal (1->2)-linked alpha-D-mannose residues in an oligo-mannose oligosaccharide. GO:0106054 tRNA U34 thiol-transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106054 tRNA-specific 2-thiouridylase|tRNA U34 2-thiouridylase Catalysis of the reaction: uridine34 in tRNA + a [TusE sulfur carrier protein]-S-sulfanylcysteine + ATP + a reduced electron acceptor = a 2-thiouridine34 in tRNA + a [TusE sulfur carrier protein]-L-cysteine + AMP + an oxidized electron acceptor + diphosphate + H+. GO:0106059 tRNA (cytidine 56-2'-O)-methyltransferase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106059 Catalysis of the reaction: S-adenosyl-L-methionine + cytidine56 in tRNA= S-adenosyl-L-homocysteine + 2'-O-methylcytidine56 in tRNA. GO:0106058 positive regulation of calcineurin-mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106058 Any process that activates or increases the frequency, rate or extent of calcineurin-mediated signaling. GO:0106057 negative regulation of calcineurin-mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106057 Any process that stops, prevents or reduces the frequency, rate or extent of calcineurin-mediated signalling. CL:0002363 keratocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002363 corneal keratocyte|corneal fibroblast A keratocyte is a specialized fibroblast residing in the cornea stroma that has a flattened, dendritic cell located between the lamellae with a large flattened nucleus and lengthy processes which communicate with neighboring cells. This corneal layer, representing about 85-90% of corneal thickness, is built up from highly regular collagenous lamellae and extracellular matrix components. Keratocytes play the major role in keeping it transparent, healing its wounds, and synthesizing its components. This cell type secretes collagen I, V, VI, and keratin sulfate. CL:0002368 respiratory epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002368 airway epithelial cell An endo-epithelial cell of the respiratory tract. CL:0002367 trabecular meshwork cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002367 trabeculocyte A cell that lines the trabecular meshwork, which is an area of tissue in the eye located around the base of the cornea, near the ciliary body, and is responsible for draining the aqueous humor from the eye via the anterior chamber (the chamber on the front of the eye covered by the cornea). This cell may play a role in regulating intraocular pressure. CL:0002369 fungal spore biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002369 A differentiated form of a fungus produced during or as a result of an asexual or sexual reproductive process; usually a cell with a thick cell wall that stores and protects one or more nuclei. Spores may be produced in response to, and are characteristically resistant to, adverse environmental conditions. GO:0106063 G protein-coupled folate receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106063 G-protein coupled folate receptor activity|G-protein coupled folic acid receptor activity Combining with folate and transmitting the signal from one side of the membrane to the other by activating an associated G-protein, initiating a change in cell activity. GO:0106062 positive regulation of exit from meiosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106062 Any process that activates or increases the frequency, rate or extent of exit from meiosis. GO:0106061 negative regulation of exit from meiosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106061 Any process that stops, prevents or reduces the frequency, rate or extent of exit from meiosis. CL:0002361 primitive erythroid progenitor biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002361 EryP-CFC|inner blood island hemangioblast A progenitor cell that is capable of forming colonies of primitive erythrocytes in the blood island of the yolk sac. First arrive at E7.5 in mouse and expresses CD41. GO:0106060 regulation of exit from meiosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106060 Any process that modulates the frequency, rate or extent of exit from mitosis. GO:0106064 regulation of cobalamin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106064 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom. CHEBI:25604 nucleotide-(amino alcohol)s biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25604 GO:0106069 synapsis initiation complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0106069 IntAct:EBI-16586568 A SUMO-E3 ligase complex capable of promoting synapsis, the meiotic cell cycle process where side by side pairing and physical juxtaposition of homologous chromosomes is created during meiotic prophase. UBERON:0012490 muscle layer of anal canal biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012490 muscular coat of anal canal|anal muscularis propria|muscularis propria of anal canal|muscular layer of anal canal|muscularis externa of anal canal|anal canal muscularis propria A muscular coat that is part of a anal canal. GO:0106068 SUMO ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0106068 SUMO-protein ligase complex|SUMO transferase complex|Sumoylation complex A protein ligase complex that enables protein sumoylation. Consists of a SUMO-protein transferase and other proteins that may confer substrate specificity of the complex. UBERON:0012499 serosa of uterine tube biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012499 serosa of oviduct|uterine tubal serosa|serosa of fallopian tube|tunica serosa (tuba uterina)|uterine tube serosa|tunica serosa tubae uterinae|serous coat of uterine tube A serous membrane that is part of a fallopian tube. CL:0002375 Schwann cell precursor biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002375 Schwann cell precursor cell A giioblast cell that develops from a migratory neural crest cell. The SCP is embedded among neurons (axons) with minimal extracellular spaces separating them from nerve cell membranes and has no basal lamina. In rodents SCPs are the only cells in the Schwann cell linage that expresses Cdh19. CL:0002374 ear hair cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002374 ear receptor cell A hair cell of the ear that contains the organs of balance and hearing. CL:0002377 immature Schwann cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002377 Schwann cell A glial cell that develops from a Schwann cell precursor. The immature Schwann cell is embedded among neurons (axons) with minimal extracellular spaces separating them from nerve cell membranes and has a basal lamina. Cells can survive without an axon present. Immature Schwann cell can be found communally ensheathing large groups of axons. GO:0106070 regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106070 regulation of adenylate cyclase-activating G-protein coupled receptor signaling pathway Any process that modulates the frequency, rate or extent of an adenylate cyclase-activating G protein-coupled receptor signaling pathway. CHEBI:25608 nucleoside phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25608 CHEBI:25605 nucleoside antibiotic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25605 GO:0106074 aminoacyl-tRNA metabolism involved in translational fidelity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106074 aminoacyl-tRNA correction|aminoacyl-tRNA editin|aminoacyl-tRNA proofreading Any process which detects an amino-acid acetylated tRNA is charged with the correct amino acid, or removes incorrect amino acids from a charged tRNA. This process can be performed by tRNA synthases, or by subsequent reactions after tRNA aminoacylation. CL:0002371 somatic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002371 A cell of an organism that does not pass on its genetic material to the organism's offspring (i.e. a non-germ line cell). GO:0106073 dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106073 RHEA:29543|EC:2.4.1.256 Catalysis of the addition of the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol. CL:0002370 respiratory goblet cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002370 respiratory mucosa goblet cells A simple columnar epithelial cell that secretes mucin. Rough endoplasmic reticulum, mitochondria, the nucleus, and other organelles are concentrated in the basal portion. The apical plasma membrane projects microvilli to increase surface area for secretion. GO:0106072 negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106072 negative regulation of adenylate cyclase-activating G-protein coupled receptor signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of an adenylate cyclase-activating G protein-coupled receptor signaling pathway. GO:0106071 positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106071 positive regulation of adenylate cyclase-activating G-protein coupled receptor signaling pathway Any process that activates or increases the frequency, rate or extent of an adenylate cyclase-activating G protein-coupled receptor signaling pathway. CL:0002372 myotube biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002372 myotubule|single cell sarcomere A transversely striated, synctial muscle cell, formed by the fusion of myoblasts. CHEBI:25609 nucleotide-sugar biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25609 NCBITaxon:480118 Eremoneura organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_480118 NCBITaxon:480117 Cyclorrhapha organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_480117 CL:0002341 basal cell of prostate epithelium biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002341 An undifferentiated cell of the prostate epithelium that lacks secretory activity. CL:1000376 Purkinje myocyte of interventricular septum biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000376 A Purkinje myocyte that is part of the interventricular septum. CL:0002344 CD56-negative, CD161-positive immature natural killer cell, human biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002344 p-NK A natural killer cell that is developmentally immature, has the phenotype CD34-negative, CD56-negative, CD117-positive, CD122-positive,and CD161-positive. GO:0106001 intestinal hexose absorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106001 Uptake of hexoses, notably D-glucose, fructose, and galactose, into the blood by absorption from the small intestine. GO:0106005 RNA 5'-cap (guanine-N7)-methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106005 The process whereby a guanine in 5-cap is methylated at the N7 position of guanine. GO:0106004 tRNA (guanine-N7)-methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106004 The process whereby a guanine in a tRNA is methylated at the N7 position of guanine. GO:0106003 amyloid-beta complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0106003 amyloid beta heterooligomer|heterotrimer of amyloid beta protein|amyloid beta homooligomer|amyloid beta trimer|Abeta-derived diffusible ligand complex|homotrimer of amyloid beta protein|beta amyloid complex|heterooligomer of amyloid beta protein|amyloid beta oligomer|homooligomer of amyloid beta protein|homodimer of amyloid beta protein|betaA complex|Abeta complex|ADDL complex|heterodimer of amyloid beta protein|amyloid beta dimer|amyloid-beta protein 42 complex|beta-amyloid complex|amyloid-beta protein 40 complex|amyloid-beta protein 40/42 complex|amyloid beta heterotrimer|amyloid beta homotrimer|amyloid beta homodimer|amyloid beta complex|amyloid beta heterodimer Protein complex involved in modulation of signaling and synaptic function in the brain, predominantly in the cerebral cortex and hippocampus. Forms dimers and multimers of amyloid beta peptide 40 and peptide 42 (proteolytic cleavage products of amyloid beta A4 protein, also known as amyloid beta precursor protein). Mostly found in the extracellular space with a proportion occurring as membrane-bound species. Influences synaptic plasticity through various receptors, mediates dendritic spine loss leading to decreased synapse density, inhibits long-term potentiation (LTP) and enhances long-term depression (LTD). Soluble multimeric form is the main pathogenic species linked to Alzheimer's disease. GO:0106002 mCRD-mediated mRNA stability complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0106002 IntAct:EBI-13948957 major coding region instability determinant-poly(A)-bridging complex|mCRD-poly(A)-bridging complex|major coding-region determinant of instability - poly(A) tail-bridging complex|major coding region determinant of instability-mediated mRNA stability complex|major coding region instability determinant-mediated mRNA stability complex A protein complex that binds to, and promotes stabilization of, mRNA molecules containing the major coding region instability determinant (mCRD) by bridging the mCRD domain and the poly(A) tail of the mRNA. In human, it consists of CSDE1, HNRPD, PABPC1, PAIP1 and SYNCRIP. GO:0106009 (4S)-4-hydroxy-2-oxoglutarate aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106009 RHEA:35639|EC:4.1.3.42 Catalysis of the reaction:(4S)-4-hydroxy-2-oxoglutarate = pyruvate + glyoxylate. GO:0023070 obsolete signal transmission via air biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023070 signal transmission via air OBSOLETE. The process in which a signal is conveyed via the air. GO:0106008 2-oxoglutaramate amidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106008 RHEA:32963|EC:3.5.1.111 Catalysis of the reaction: 2-oxoglutaramate + H(2)O = 2-oxoglutarate + NH(3). GO:0106007 microtubule anchoring at cell cortex of cell tip biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106007 Any process in which a microtubule is maintained in a specific location at the cell tip by attachment to the cell cortex. GO:0106006 cytoskeletal protein-membrane anchor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106006 cytoskeletal protein-membrane adaptor activity|F-BAR domain adaptor|microtubule cortical anchor activity|cytoskeletal protein membrane adaptor|BAR domain adaptor|membrane-cytoskeletal protein tether activity|cytoskeletal protein membrane tether activity|membrane-cytoskeletal protein anchor activity|cytoskeletal protein membrane anchor activity The binding activity of a molecule that brings together a cytoskeletal protein or protein complex and a plasma membrane lipid or membrane-associated protein, in order to maintain the localization of the cytoskeleton at a specific cortical membrane location. CL:0002353 fetal liver hematopoietic progenitor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002353 A hematopoietic stem cell that resides in the fetal liver. In mice, this cell type is first observed at E10.5. This cell type is MHC-positive, HSA-positive, AA4.1-positive, CD45-positive, Sca-1 positive, CD150-positive, CD48-negative and CD244-negative. CL:0002352 gestational hematopoietic stem cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002352 A hematopoietic stem cell that exists during embryogenesis. CL:0002355 primitive red blood cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002355 primitive erythroblast|primitive erythrocyte|primitive erythroid cell A large nucleated basophilic erythrocyte found in mammalian embryos. This cell type arises from the blood islands of yolk sacs and expresses different types of hemoglobins (beta-H1, gamma-1 and zeta) than adult erythrocytes. Considered a type of erythroblast as this cell type can enucleate in circulation. CL:0002354 yolk sac hematopoietic stem cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002354 hemangioblast precursor A hematopoietic stem found in the yolk sac. In mice, this cell type is Sca-1-negative, CD45-negative, MHC-negative, HSA-positive, AA4.1-positive, CD44-positive. CL:0002357 fetal derived definitive erythrocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002357 macrocyte A fetal liver derived enucleated erythrocyte. This erythrocyte resembles adult erythrocytes in that they are small (3- to 6- times smaller than primitive erythrocytes) and produce adult hemaglobins. CL:0002356 primitive reticulocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002356 megalocyte A primitive erythrocyte that has undergone enucleation. This cell type is 3-6 fold bigger than the fetal derived erythrocytes that they co-circulate with during fetal development. Expresses epsilon-gamma hemoglobin chains. CL:0002359 placental hematopoietic stem cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002359 A hematopoietic stem cell of the placenta. This cell type is first observed E10.5 This cell type may give rise to fetal liver hematopoietic stem cells. CL:0002358 pyrenocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002358 Derived from the Greek word pyren (the pit of a stone fruit), this is a transient nucleated cell type that results from exclusion of the nucleus from the primitive erythrocyte. CL:0002351 progenitor cell of endocrine pancreas biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002351 pancreatic endocrine progenitor|pancreatic islet progenitor cell A multi-fate stem cell that is able to differentiate into the pancreas alpha, beta and delta endocrine cells. This cell type expresses neurogenin-3 and Isl-1. CL:0002350 endocardial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002350 endocardial endothelial cell|endothelial cell of endocardium An endothelial cell that lines the intracavitary lumen of the heart, separating the circulating blood from the underlying myocardium. This cell type releases a number of vasoactive substances including prostacyclin, nitrous oxide and endothelin. GO:0023067 obsolete signal transmission via lymphatic system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023067 signal transmission via lymphatic system OBSOLETE. The process in which a signal is conveyed via the lymphatic system. GO:0106012 positive regulation of protein localization to medial cortex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106012 Any process that activates or increases the frequency, rate or extent of protein localization to the medial cortex. GO:0023066 obsolete signal transmission via vascular system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023066 signal transmission via vascular system OBSOLETE. The process in which a signal is conveyed via the vascular system. GO:0106011 regulation of protein localization to medial cortex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106011 Any process that regulates the localization of a protein to the medial cortex. GO:0023069 obsolete signal transmission via xylem biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023069 signal transmission via xylem OBSOLETE. The process in which a signal is conveyed via the xylem. GO:0023068 obsolete signal transmission via phloem biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023068 signal transmission via phloem OBSOLETE. The process in which a signal is conveyed via the phloem. GO:0106016 positive regulation of inflammatory response to wounding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106016 Any process that activates or increases the frequency, rate or extent of the inflammatory response to wounding. GO:0106015 negative regulation of inflammatory response to wounding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106015 Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response to wounding. GO:0106014 regulation of inflammatory response to wounding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106014 Any process that modulates the frequency, rate or extent of the inflammatory response to wounding. GO:0106013 negative regulation of protein localization to cell cortex of cell tip biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106013 Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to the cell cortex of the cell tip. CL:0002328 bronchial epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002328 An epithelial cell of the bronchus. GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106019 Catalysis of the reaction: 1-phosphatidyl-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol phosphate + phosphate. CL:0002327 mammary gland epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002327 mammary epithelial cell|breast epithelial cell An epithelial cell of the mammary gland. GO:0023061 signal release biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023061 signal secretion The process in which a signal is secreted or discharged into the extracellular medium from a cellular source. GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106018 Catalysis of the reaction: 1-phosphatidyl-myo-inositol 3,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol phosphate + phosphate. GO:0023060 obsolete signal transmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023060 signal transmission OBSOLETE. The process in which a signal is released and/or conveyed from one location to another. GO:0106017 phosphatidylinositol-3,4-bisphosphate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106017 Catalysis of the reaction: 1-phosphatidyl-myo-inositol 3,4-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol phosphate + phosphate. CL:0002329 basal epithelial cell of tracheobronchial tree biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002329 An epithelial cell type that lacks the columnar shape typical for other respiratory epithelial cells. This cell type is able to differentiate into other respiratory epithelial cells in response to injury. GO:0023062 obsolete signal transmission via transcytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023062 signal transmission via transcytosis OBSOLETE. The process in which a signal is conveyed via transcytosis. Transcytosis is the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. GO:0023065 obsolete signal transmission via blood biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023065 signal transmission via blood OBSOLETE. The process in which a signal is conveyed via blood. CHEBI:142198 purine 2'-deoxyribonucleoside 5'-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142198 CL:0002320 connective tissue cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002320 A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone. CL:0002322 embryonic stem cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002322 ESC A stem cell of embryonic origin. CL:0002321 embryonic cell (metazoa) biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002321 A cell of the embryo. CL:0002323 amniocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002323 A cell of a fetus which is suspended in the amniotic fluid. Amniocytes are considered to arise from several tissues including fetal skin, the fetal urinary tract, umbilical cord, and the inner amniotic surface. CL:0002325 mammary alveolar cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002325 epithelial cell of lactiferous gland|luminal cell of alveolus of lactiferous gland The milk-producing cell of the alveolar unit that emerges during pregnancy. CL:1000391 melanocyte of eyelid biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000391 sebaceous gland of wolff|eyelid melanocyte A melanocyte that is part of the eyelid. GO:0023056 positive regulation of signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023056 positive regulation of signalling process|positive regulation of signaling process Any process that activates, maintains or increases the frequency, rate or extent of a signaling process. GO:0047001 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047001 MetaCyc:1.1.1.127-RXN|RHEA:24232|EC:1.1.1.127 2-keto-3-deoxy-D-gluconate (3-deoxy-D-glycero-2,5-hexodiulosonic acid) dehydrogenase activity|2-keto-3-deoxygluconate 5-dehydrogenase activity|2-keto-3-deoxygluconate (nicotinamide adenine dinucleotide (phosphate)) dehydrogenase activity|2-keto-3-deoxygluconate dehydrogenase activity|2-dehydro-3-deoxy-D-gluconate:NAD+ 5-oxidoreductase activity Catalysis of the reaction: NAD+ + 2-dehydro-3-deoxy-D-gluconate = NADH + (4S)-4,6-dihydroxy-2,5-dioxohexanoate. GO:0106023 regulation of pupariation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106023 Any process that modulates the onset of pupariation. GO:0106022 positive regulation of vesicle docking biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106022 positive regulation of vesicle to membrane docking Any process that activates or increases the frequency, rate or extent of vesicle docking. GO:0023055 obsolete signal initiation by peptide hormone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023055 signal initiation by peptide hormone OBSOLETE. The process in which a signal is initiated by a peptide hormone. GO:0047000 2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047000 RHEA:15109|KEGG_REACTION:R01543|MetaCyc:1.1.1.126-RXN|EC:1.1.1.126 2-dehydro-3-deoxy-D-gluconate:NADP+ 6-oxidoreductase activity|2-keto-3-deoxy-D-gluconate dehydrogenase activity Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate + NADP(+) = (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + H(+) + NADPH. GO:0023058 adaptation of signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023058 adaptation of signalling pathway The regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus. GO:0106021 negative regulation of vesicle docking biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106021 negative regulation of vesicle to membrane docking Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle docking. GO:0106020 regulation of vesicle docking biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106020 regulation of vesicle to membrane docking Any process that modulates the frequency, rate or extent of vesicle docking. GO:0023057 negative regulation of signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023057 negative regulation of signalling process|negative regulation of signaling process Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process. GO:0106027 neuron projection organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106027 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a neuron, e.g. an axon, or a dendrite. GO:0023059 positive adaptation of signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023059 positive adaptation of signalling pathway The positive regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus. GO:0106026 Gly-tRNA(Ala) hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106026 Catalysis of the hydrolysis of misacylated Gly-tRNA(Ala). GO:0106025 positive regulation of pupariation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106025 Any process that activates or increases the frequency, rate or extent of onset of pupariation. GO:0106024 negative regulation of pupariation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106024 Any process that stops, prevents or reduces the rate of onset of pupariation. GO:0047009 3-alpha-hydroxy-5-beta-androstane-17-one 3-alpha-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047009 RHEA:10356|MetaCyc:1.1.1.152-RXN|EC:1.1.1.152 3alpha-hydroxy-5beta-steroid dehydrogenase activity|etiocholanolone 3alpha-dehydrogenase activity|3alpha-hydroxy-5beta-androstane-17-one 3alpha-dehydrogenase activity|etiocholanolone 3-alpha-dehydrogenase activity|3alpha-hydroxy-5beta-steroid:NAD+ 3-oxidoreductase activity Catalysis of the reaction: NAD+ + 3-alpha-hydroxy-5-beta-androstane-17-one = NADH + H+ + 5-beta-androstane-3,17-dione. CL:0002339 prostate stem cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002339 CD133-positive prostate epithelial cell A prostate epithelial cell that is CD133-positive, CD44-positive, integrin A2beta3-high. This cell is a stem cell for the prostate epithelium. CL:0002338 CD56-positive, CD161-positive immature natural killer cell, human biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002338 p-NK A natural killer cell that is developmentally immature, has the phenotype CD34-negative, CD56-positive, CD117-positive, CD122-positive,and CD161-positive. GO:0047008 pregnan-21-ol dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047008 RHEA:23712|KEGG_REACTION:R03044|MetaCyc:1.1.1.151-RXN|EC:1.1.1.151 21-hydroxysteroid:NADP+ 21-oxidoreductase activity|21-hydroxy steroid dehydrogenase (nicotinamide adenine dinucleotide phosphate) activity|21-hydroxy steroid (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity|21-hydroxysteroid dehydrogenase (NADP+) activity|21-hydroxy steroid dehydrogenase activity|NADP-21-hydroxysteroid dehydrogenase activity Catalysis of the reaction: NADP(+) + pregnan-21-ol = H(+) + NADPH + pregnan-21-al. GO:0106029 tRNA pseudouridine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106029 RHEA:22376|EC:5.4.99.28|EC:5.4.99.27|EC:5.4.99.26|EC:5.4.99.25|EC:5.4.99.45|EC:5.4.99.12|EC:5.4.99.44|EC:5.4.99.42|MetaCyc:TRNA-PSEUDOURIDINE-SYNTHASE-I-RXN tRNA pseudouridine(13) synthase|tRNA pseudouridine(55) synthase|tRNA pseudouridine(65) synthase|tRNA pseudouridine(32) synthase|tRNA pseudouridine(38/39) synthase|transfer ribonucleate pseudouridine synthetase activity|tRNA-pseudouridine synthase activity|tRNA-uridine isomerase activity|transfer RNA pseudouridine synthetase activity|tRNA pseudouridylate synthase I activity|Mitochondrial tRNA pseudouridine(27/28) synthase|tRNA pseudouridine(38-40) synthase|tRNA-pseudouridine synthase I activity|tRNA pseudouridine(31) synthase|tRNA-uridine uracilmutase activity Catalysis of the reaction: tRNA uridine = tRNA pseudouridine. Conversion of uridine in a tRNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5. GO:0023050 obsolete consequence of signal transmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023050 consequence of signal transmission|signal termination OBSOLETE. The steps whereby the downstream processes started by a signal are brought to a conclusion. Examples include destruction of cAMP by PDE, or endocytosis resulting from receptor phosphorylation. The termination process ends when the receptor has returned to its inactive state. GO:0047007 pregnan-21-ol dehydrogenase (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047007 RHEA:11448|KEGG_REACTION:R03043|MetaCyc:1.1.1.150-RXN|EC:1.1.1.150 21-hydroxysteroid dehydrogenase (NAD+) activity|21-hydroxysteroid:NAD+ 21-oxidoreductase activity Catalysis of the reaction: NAD(+) + pregnan-21-ol = H(+) + NADH + pregnan-21-al. GO:0106028 neuron projection retraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106028 neuron projection disassembly The organization process which results in the disassembly (either partial or complete) of constituent parts of a neuron projection. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite. GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047006 MetaCyc:1.1.1.149-RXN|EC:1.1.1.149 20alpha-hydroxysteroid:NAD(P)+ 20-oxidoreductase activity|20alpha-HSD|20alpha-hydroxysteroid dehydrogenase|20alpha-HSDH|20alpha-hydroxy steroid dehydrogenase activity Catalysis of the reaction: NAD(P)+ + 17-alpha,20-alpha-dihydroxypregn-4-en-3-one = NAD(P)H + H+ + 17-alpha-hydroxyprogesterone. GO:0047005 16-alpha-hydroxysteroid dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047005 MetaCyc:1.1.1.147-RXN|EC:1.1.1.147 16alpha-hydroxy steroid dehydrogenase activity|16alpha-hydroxysteroid dehydrogenase activity|16alpha-hydroxysteroid:NAD(P)+ 16-oxidoreductase activity Catalysis of the reaction: NADP+ + 16-alpha-hydroxysteroid = NADPH + H+ + 16-oxosteroid. GO:0023052 signaling biolink:BiologicalProcess go-plus goslim_pombe|goslim_flybase_ribbon|goslim_mouse|goslim_yeast|goslim_agr http://purl.obolibrary.org/obo/GO_0023052 single organism signaling|signalling|biological signaling|signaling process|signalling process The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered. GO:0023051 regulation of signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023051 regulation of signaling process|regulation of signalling process Any process that modulates the frequency, rate or extent of a signaling process. GO:0047004 UDP-N-acetylglucosamine 6-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047004 KEGG_REACTION:R00421|RHEA:13325|MetaCyc:1.1.1.136-RXN|EC:1.1.1.136 UDPacetylglucosamine dehydrogenase activity|UDP-N-acetyl-D-glucosamine:NAD+ 6-oxidoreductase activity|uridine diphosphoacetylglucosamine dehydrogenase activity|UDP-2-acetamido-2-deoxy-D-glucose:NAD oxidoreductase activity|UDP-GLcNAc dehydrogenase activity Catalysis of the reaction: H(2)O + 2 NAD(+) + UDP-N-acetyl-alpha-D-glucosamine = 3 H(+) + 2 NADH + UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate. GO:0047003 dTDP-6-deoxy-L-talose 4-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047003 RHEA:23648|KEGG_REACTION:R02776|MetaCyc:1.1.1.134-RXN|EC:1.1.1.134 dTDP-6-deoxy-L-talose dehydrogenase (4-reductase)|dTDP-6-deoxy-L-talose:NADP+ 4-oxidoreductase activity|TDP-6-deoxy-L-talose dehydrogenase activity|thymidine diphospho-6-deoxy-L-talose dehydrogenase activity Catalysis of the reaction: dTDP-6-deoxy-L-talose + NADP(+) = dTDP-4-dehydro-6-deoxy-L-mannose + H(+) + NADPH. GO:0023054 obsolete signal initiation by stretch effect biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023054 signal initiation by stretch effect OBSOLETE. The process in which a stretch signal causes activation of a receptor. GO:0047002 L-arabinitol 2-dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047002 EC:1.1.1.13|RHEA:21356|KEGG_REACTION:R02441|MetaCyc:1.1.1.13-RXN L-arabinitol 2-dehydrogenase (ribulose forming) activity Catalysis of the reaction: L-arabinitol + NAD(+) = L-ribulose + H(+) + NADH. GO:0023053 obsolete signal initiation by mechanical effect biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0023053 signal initiation by mechanical effect OBSOLETE. The process in which a mechanical signal causes activation of a receptor. CL:0002333 neural crest derived fat cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002333 A fat cell derived from a neural crest cell. CL:0002332 ciliated cell of the bronchus biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002332 A ciliated cell of the bronchus. CL:0002335 brown preadipocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002335 A preadipocyte that is capable of differentiating into a brown adipocyte. This cell type expresses uncoupling protein-1, PPAR-gamma, PR-domain-containing 16; and PGC-1alpha (peroxisome proliferator-activated receptor-gamma (PPARgamma) coactivator-1alpha). CL:0002334 preadipocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002334 An undifferentiated fibroblast that can be stimulated to form a fat cell. GO:0106030 neuron projection fasciculation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106030 The collection of neuronal projections into a bundle of rods, known as a fascicle. CHEBI:132809 (8S)-hepoxilin A3 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132809 CHEBI:49544 chromium(3+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49544 CHEBI:50533 protein denaturant biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50533 CHEBI:132808 (8S)-hydroperoxy-(14S,15R)-epoxy-(5Z,9E,11Z)-icosatrienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132808 CHEBI:74503 Ins-1-P-Cer-A(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74503 CHEBI:25576 nonadienedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25576 CHEBI:50532 (S)-beta-alanopine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50532 CHEBI:74502 N(3)-methyluridine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74502 CHEBI:50531 (R)-beta-alanopine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50531 CHEBI:25575 nonadienedioate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25575 CHEBI:74505 Ins-1-P-Cer-A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74505 CHEBI:74504 (17Z,20Z,23Z,26Z)-3-oxodotriacontatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74504 CHEBI:74506 N(4)-methylcytidine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74506 CHEBI:25579 nonanone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25579 CHEBI:132801 18(S)-HEPE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132801 CHEBI:132800 17-oxoresolvin D1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132800 CHEBI:74508 5-carboxymethylaminomethyluridine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74508 CHEBI:132803 UDP-N-acetyl-alpha-D-galactosamine 4,6-bissulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132803 CHEBI:132802 (5S)-hydroperoxy-(18S)-hydroxy-(6E,8Z,11Z,14Z,16E)-icosapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132802 CHEBI:132805 beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-D-GlcpNAc biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132805 CHEBI:132804 UDP-N-acetyl-alpha-D-galactosamine 4-sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132804 CL:1000458 melanocyte of skin biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000458 skin melanocyte A melanocyte that is part of the skin of body. CL:1000457 mesothelial cell of visceral peritoneum biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000457 A mesothelial cell that is part of the visceral peritoneum. CHEBI:25572 nocardicin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25572 CL:1000456 mesothelial cell of parietal peritoneum biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000456 A mesothelial cell that is part of the parietal peritoneum. CL:1000450 epithelial cell of glomerular capsule biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000450 epithelial cell of Bowman's capsule|Bowmans capsule epithelial cell An epithelial cell that is part of the glomerular capsule. CHEBI:50523 butenolide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50523 CHEBI:74512 (17Z,20Z,23Z,26Z)-dotriacontatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74512 CHEBI:74511 5-carboxymethylaminomethyl-2'-O-methyluridine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74511 CHEBI:50521 N-methylnicotinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50521 CHEBI:74513 N(2),N(2)-dimethylguanosine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74513 CHEBI:74515 (19Z,22Z,25Z,28Z)-3-oxotetratriacontatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74515 CHEBI:49537 c-di-GMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49537 CHEBI:50526 phenolate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50526 CHEBI:74518 anti-obesity agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74518 CHEBI:50525 phenolate anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50525 CHEBI:50524 catecholate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50524 CHEBI:74519 (19Z,22Z,25Z,28Z)-tetratriacontatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74519 CHEBI:132814 beta-D-Galp-(1->3)-beta-D-GalpNAc-(1->4)-beta-D-Galp-(1->4)-D-Glcp biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132814 CHEBI:50528 FMNH(.) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50528 CL:1000449 epithelial cell of nephron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000449 An epithelial cell that is part of the nephron. CHEBI:25585 nonmetal atom biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25585 CL:1000448 epithelial cell of sweat gland biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000448 An epithelial cell that is part of the sweat gland. CHEBI:132818 apigenin 7-O-beta-L-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132818 CL:1000443 ciliary muscle cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000443 smooth muscle cell of ciliary body A smooth muscle cell that is part of the ciliary body. CHEBI:50511 bipyridines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50511 CHEBI:74522 (21Z,24Z,27Z,30Z)-3-oxohexatriacontatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74522 CHEBI:25555 nitrogen atom biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25555 CHEBI:50510 potassium channel modulator biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50510 CHEBI:74525 (21Z,24Z,27Z,30Z)-hexatriacontatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74525 CHEBI:50516 (24R)-24-hydroxycholesterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50516 CHEBI:50515 24-hydroxycholesterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50515 CHEBI:50514 vasoconstrictor agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50514 CHEBI:74529 antidote to paracetamol poisoning biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74529 CHEBI:25558 organonitrogen heterocyclic antibiotic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25558 CHEBI:50513 mydriatic agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50513 CHEBI:50519 sulfoacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50519 CHEBI:50517 7alpha,24-dihydroxycholesterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50517 UBERON:0036553 wall of synovial tendon sheath biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036553 CHEBI:25550 nitroaniline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25550 CL:1000479 Purkinje myocyte of atrioventricular node biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000479 A Purkinje myocyte that is part of the atrioventricular node. CHEBI:25567 nitrous acid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_25567 CHEBI:25566 nitrotoluene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25566 CHEBI:74535 N-[(15Z)-tetracosenoyl]sphing-4-enine-1-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74535 CHEBI:50505 sweetening agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50505 CHEBI:50504 osmotic diuretic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50504 CHEBI:50503 laxative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50503 CHEBI:50502 EC 2.5.1.15 (dihydropteroate synthase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50502 CHEBI:50509 potassium channel blocker biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50509 CHEBI:25562 nitrophenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25562 CHEBI:25560 nitroglycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25560 CL:1000465 chromaffin cell of ovary biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000465 A chromaffin cell that is part of the ovary. CHEBI:74530 antidote to curare poisoning biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74530 CHEBI:25534 nicotinic acid nucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25534 CHEBI:74544 1-oleoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74544 CHEBI:25533 N-glycosylnicotinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25533 CHEBI:74547 1-linoleoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74547 CHEBI:74546 1,2-dioleoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74546 CHEBI:74549 1-linolenoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74549 CHEBI:74548 1-linoleoyl-2-oleoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74548 CL:1000415 epithelial cell of gall bladder biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000415 An epithelial cell that is part of the gallbladder. CL:1000413 endothelial cell of artery biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000413 arterial endothelial cell A blood vessel endothelial cell that is part of an arterial endothelium. CL:0002188 glomerular endothelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002188 An endothelial cell found in the glomerulus of the kidney. This cell is flattened, highly fenestrated, and plays a vital role in the formation of glomerular ultrafiltrate. CL:1000410 myocyte of atrioventricular node biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000410 AV nodal myocyte|atrioventricular node cell|AV node cardiac muscle cell|AV node cell|atrioventricular node myocyte A muscle cell that is part of the atrioventricular node. CL:0002187 basal cell of epidermis biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002187 A basally situated, mitotically active, columnar-shaped keratinocyte attached to the basement membrane. CHEBI:74543 8-methyladenosine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74543 CHEBI:74556 1-heptadecanoyl-2-oleoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74556 CHEBI:74558 1-oleoyl-2-heptadecanoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74558 CHEBI:25548 nitrilotriacetate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_25548 CL:1000409 myocyte of sinoatrial node biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000409 SA nodal myocyte|myocyte of sinoatrial node|SA node cardiac muscle cell|sinoatrial node myocyte|sinuatrial node myocyte|sinoatrial node cell A muscle cell that is part of the sinoatrial node. CHEBI:25540 neonicotinoid insectide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25540 CL:0002191 granulocytopoietic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002191 A cell involved in the formation of a granulocyte. CL:0002193 myelocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002193 A cell type that is the first of the maturation stages of the granulocytic leukocytes normally found in the bone marrow. Granules are seen in the cytoplasm. The nuclear material of the myelocyte is denser than that of the myeloblast but lacks a definable membrane. The cell is flat and contains increasing numbers of granules as maturation progresses. CHEBI:74550 1-linolenoyl-2-oleoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74550 CL:0002192 metamyelocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002192 A eosinophil precursor in the granulocytic series, being a cell intermediate in development between a myelocyte and a band form cell. The nucleus becomes indented where the indentation is smaller than half the distance to the farthest nuclear margin; chromatin becomes coarse and clumped; specific granules predominate while primary granules are rare. CL:0002195 hepatic stem cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002195 A stem cell that can give rise to the cells of the liver. CHEBI:74552 1-oleoyl-2-stearoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74552 CHEBI:74551 1-oleoyl-2-palmitoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74551 CL:0002194 monopoietic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002194 A cell involved in the formation of a monocyte (monopoiesis). CHEBI:74554 1-heptadecanoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74554 CHEBI:25512 neurotransmitter biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25512 CHEBI:25516 nickel cation biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_25516 CHEBI:25513 neutral glycosphingolipid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25513 CL:0002167 olfactory epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002167 A specialized cell involved in sensory perception of smell. OIO:shorthand shorthand biolink:OntologyClass go-plus http://www.geneontology.org/formats/oboInOwl#shorthand CHEBI:25519 nickel tetrapyrrole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25519 CHEBI:74560 1-stearoyl-2-oleoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74560 CHEBI:74563 1-oleoyl-2-linoleoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74563 CHEBI:74565 1-stearoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74565 CHEBI:25523 NADP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25523 CHEBI:74578 1-oleoyl-2-pentadecanoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74578 CHEBI:74577 1-acyl-2-arachidonoyl-sn-glycero-3-phospho-D-myo-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74577 CHEBI:74579 1-oleoyl-2-myristoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74579 CHEBI:25520 nicotianamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25520 CHEBI:25527 nicotinamide nucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25527 CHEBI:25526 N-glycosylnicotinamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25526 CHEBI:25524 NAD(P) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25524 UBERON:0036521 wall of urethra biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036521 urethral wall CL:1000428 stem cell of epidermis biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000428 epidermal stem cell A somatic stem cell that is part of the epidermis. CL:1000427 adrenal cortex chromaffin cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000427 chromaffin cell of adrenal cortex A chromaffin cell that is part of the adrenal cortex. UBERON:0036523 wall of vagina biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036523 vaginal wall CL:1000426 chromaffin cell of adrenal gland biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000426 adrenal chromaffin cell A chromaffin cell that is part of the adrenal gland. CL:0002178 epithelial cell of stomach biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002178 An epithelial cell found in the lining of the stomach. CHEBI:74572 (23Z,26Z,29Z,32Z)-3-oxooctatriacontatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74572 CHEBI:25529 pyridinecarboxamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25529 CHEBI:74574 pentadecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74574 CHEBI:74576 1-acyl-2-(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-sn-glycero-3-phospho-D-myo-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74576 CL:0002174 follicular cell of ovary biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002174 A cell within the follicle of an ovary. CHEBI:74575 (9Z)-pentadecenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74575 GO:0072177 mesonephric duct development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072177 Wolffian duct development The process whose specific outcome is the progression of a mesonephric duct over time, from its initial formation to a mature structure. A mesonephric duct is a tube drains the mesonephros. GO:0072176 nephric duct development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072176 The process whose specific outcome is the progression of a nephric duct over time, from its initial formation to a mature structure. A nephric duct is a tube that drains a primitive kidney. GO:0072175 epithelial tube formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072175 The developmental process pertaining to the initial formation of an epithelial tube. GO:0072174 metanephric tubule formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072174 The developmental process pertaining to the initial formation of a metanephric tubule. GO:0072173 metanephric tubule morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072173 The process in which the anatomical structures of a metanephric tubule are generated and organized from an epithelium. A metanephric tubule is an epithelial tube that is part of the metanephros. GO:0072172 mesonephric tubule formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072172 The developmental process pertaining to the initial formation of a mesonephric tubule from unspecified parts. A mesonephric tubule is an epithelial tube that is part of the mesonephros. GO:0072171 mesonephric tubule morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072171 The process in which the anatomical structures of a mesonephric tubule are generated and organized. A mesonephric tubule is an epithelial tube that is part of the mesonephros. GO:0072170 metanephric tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072170 The progression of a metanephric tubule over time, from its initial formation to the mature structure. A metanephric tubule is an epithelial tube that is part of the metanephros. CHEBI:132883 11(S),15(S)-dihydroxy-14(R)-(S-glutathionyl)-5(Z),8(Z),12(E)-icosatrienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132883 CHEBI:132886 11(S)-hydroxy-14(S),15(S)-hepoxilin A3 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132886 GO:0072179 nephric duct formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072179 The developmental process pertaining to the initial formation of a nephric duct. A nephric duct is a tube that drains a primitive kidney. GO:0072178 nephric duct morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072178 The process in which the anatomical structures of the nephric duct are generated and organized. A nephric duct is a tube that drains a primitive kidney. GO:0072166 posterior mesonephric tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072166 The progression of the posterior mesonephric tubule over time, from its initial formation to the mature structure. The posterior mesonephric tubule is an epithelial tube that is part of the mesonephros. GO:0072165 anterior mesonephric tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072165 The progression of the anterior mesonephric tubule over time, from its initial formation to the mature structure. The anterior mesonephric tubule is an epithelial tube that is part of the mesonephros. GO:0072164 mesonephric tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072164 The progression of a mesonephric tubule over time, from its initial formation to the mature structure. A mesonephric tubule is an epithelial tube that is part of the mesonephros. GO:0072163 mesonephric epithelium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072163 The process whose specific outcome is the progression of an epithelium in the mesonephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. GO:0072162 metanephric mesenchymal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072162 The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the metanephros as it progresses from its formation to the mature state. GO:0072161 mesenchymal cell differentiation involved in kidney development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072161 The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the kidney as it progresses from its formation to the mature state. GO:0072160 nephron tubule epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072160 The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the nephron tubule as it progresses from its formation to the mature state. CHEBI:142209 pyrimidine 2'-deoxyribonucleoside 5'-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142209 GO:0072169 specification of posterior mesonephric tubule identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072169 The process in which the tubules of the posterior mesonephros acquire their identity. GO:0072168 specification of anterior mesonephric tubule identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072168 The process in which the tubules of the anterior mesonephros acquire their identity. GO:0072167 specification of mesonephric tubule identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072167 The process in which the tubules of the mesonephros acquire their identity. GO:0072199 regulation of mesenchymal cell proliferation involved in ureter development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072199 regulation of ureteral mesenchymal cell proliferation|regulation of ureter mesenchymal cell proliferation Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. GO:0072198 mesenchymal cell proliferation involved in ureter development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072198 ureter mesenchymal cell proliferation|ureteral mesenchymal cell proliferation The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureter, that contributes to ureter development. CHEBI:50599 N(tele)-methyl-L-histidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50599 GO:0072197 ureter morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072197 The process in which the anatomical structures of the ureter are generated and organized. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder. GO:0072196 proximal/distal pattern formation involved in pronephric nephron development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072196 pronephros proximal/distal pattern formation The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of the pronephros. GO:0072195 kidney smooth muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072195 The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell in the kidney. GO:0072194 kidney smooth muscle tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072194 The process whose specific outcome is the progression of smooth muscle in the kidney over time, from its formation to the mature structure. GO:0072193 ureter smooth muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072193 The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell in the ureter. GO:0072192 ureter epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072192 The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell in the urothelium. The urothelium is the epithelial tube of the ureter. GO:0072191 ureter smooth muscle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072191 The process whose specific outcome is the progression of smooth muscle in the ureter over time, from its formation to the mature structure. GO:0072190 ureter urothelium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072190 ureter epithelium development The process whose specific outcome is the progression of the urothelium of the ureter over time, from its formation to the mature structure. The urothelium is an epithelium that makes up the epithelial tube of the ureter. CHEBI:50591 4beta-methylzymosterol-4alpha-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50591 CHEBI:50593 3-dehydro-4-methylzymosterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50593 GO:0072188 metanephric cap specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072188 The process in which the metanephric cap acquires its identity. GO:0072187 metanephric cap formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072187 The developmental process pertaining to the initial formation of a metanephric cap from unspecified parts. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip. GO:0072186 metanephric cap morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072186 The process in which the anatomical structures of the metanephric cap are generated and organized. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip. GO:0072185 metanephric cap development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072185 The biological process whose specific outcome is the progression of the metanephric cap from an initial condition to its mature state. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip. CHEBI:50586 9xi-episterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50586 GO:0072184 renal vesicle progenitor cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072184 The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the renal vesicle progenitor cells of the kidney as it progresses from its formation to the mature state. A renal vesicle progenitor cell is a cell that will give rise to terminally differentiated cells of the renal vesicle without self-renewing. GO:0072183 negative regulation of nephron tubule epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072183 Any process that decreases the frequency, rate or extent of nephron tubule epithelial cell differentiation. GO:0072182 regulation of nephron tubule epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072182 Any process that modulates the frequency, rate or extent of nephron tubule epithelial cell differentiation. GO:0072181 mesonephric duct formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072181 Wolffian duct formation The developmental process pertaining to the initial formation of a mesonephric duct. A mesonephric duct is a tube that drains the mesonephros. GO:0072180 mesonephric duct morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072180 Wolffian duct morphogenesis The process in which the anatomical structures of the mesonephric duct are generated and organized. A mesonephric duct is a tube drains the mesonephros. CHEBI:132877 4-O-[(2R)-1-glycerylphosphono]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl undecaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132877 CHEBI:132876 beta-D-glucosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl undecaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132876 CHEBI:132875 N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl undecaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132875 CHEBI:50584 alkyl alcohol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50584 CHEBI:50583 3-hydroxyoctadecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50583 GO:0072189 ureter development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072189 The process whose specific outcome is the progression of the ureter over time, from its formation to the mature structure. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut. CHEBI:50582 alkenyl alcohol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50582 CHEBI:50578 3-hydroxyoctadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50578 CHEBI:50576 3-oxooctadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50576 CHEBI:50570 trans-2-octadecenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50570 CHEBI:50574 octadec-2-ene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50574 CHEBI:50573 octadec-2-enoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50573 CHEBI:50572 trans-octadec-2-enoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50572 CHEBI:50571 3-oxooctadecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50571 CHEBI:50566 nitric oxide donor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50566 CHEBI:50565 N-acetyl-beta-D-glucosamine 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50565 CHEBI:49575 diazepam biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49575 UBERON:0012504 adventitia of esophagus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012504 adventitia of oesophagus|esophageal adventitia|esophagus adventitia|adventitious layer of esophagus|tunica adventitia oesophageae|tunica adventitia (esophagus) A adventitia that is part of a esophagus. CHEBI:50563 iridoid monoterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50563 CHEBI:50562 tartrate salt biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50562 CHEBI:25591 norcoclaurine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25591 CHEBI:50545 trans-isoeugenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50545 CHEBI:50544 (-)-menthofuran biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50544 CHEBI:50542 menthofuran biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50542 CHEBI:50549 (beta-D-ribofuranosyl)uric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50549 CHEBI:50547 3-(beta-D-ribofuranosyl)uric acid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50547 CHEBI:49552 copper(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49552 CHEBI:132832 (+)-alpha-gurjunene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132832 CHEBI:50540 (S)-cis-N-methylcanadine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50540 GO:0047133 dimethylamine dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047133 RHEA:10204|MetaCyc:1.5.8.1-RXN|EC:1.5.8.1|UM-BBD_reactionID:r1380 DMADh activity|dimethylamine:electron-transferring flavoprotein oxidoreductase activity Catalysis of the reaction: electron-transferring flavoprotein + H2O + dimethylamine = reduced electron-transferring flavoprotein + formaldehyde + methylamine. GO:0047132 dihydrobenzophenanthridine oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047132 EC:1.5.3.12|RHEA:16621|MetaCyc:1.5.3.12-RXN dihydrobenzophenanthridine:oxygen oxidoreductase activity Catalysis of the reaction: O2 + dihydrosanguinarine = H2O2 + sanguinarine. GO:0047131 saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047131 MetaCyc:1.5.1.9-RXN|KEGG_REACTION:R02313|EC:1.5.1.9|RHEA:24520|Reactome:R-HSA-70940 saccharopin dehydrogenase activity|NAD+ oxidoreductase (L-2-aminoadipic-delta-semialdehyde and glutamate forming)|6-N-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-glutamate-forming)|aminoadipic semialdehyde synthase activity|dehydrogenase, saccharopine (nicotinamide adenine dinucleotide, glutamate-forming)|N6-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-glutamate-forming) Catalysis of the reaction: L-saccharopine + H(2)O + NAD(+) = L-glutamate + allysine + H(+) + NADH. GO:0047130 saccharopine dehydrogenase (NADP+, L-lysine-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047130 MetaCyc:1.5.1.8-RXN|EC:1.5.1.8|RHEA:19373|Reactome:R-HSA-70938|KEGG_REACTION:R00716 N6-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)|lysine:alpha-ketoglutarate:TPNH oxidoreductase (epsilon-N-[gultaryl-2]-L-lysine forming)|L-lysine-alpha-ketoglutarate reductase activity|saccharopine (nicotinamide adenine dinucleotide phosphate, lysine-forming) dehydrogenase activity|6-N-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming) Catalysis of the reaction: L-saccharopine + H(2)O + NADP(+) = 2-oxoglutarate + L-lysine + H(+) + NADPH. GO:1904959 regulation of cytochrome-c oxidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904959 regulation of cytochrome aa3 activity|regulation of cytochrome a3 activity|regulation of ferrocytochrome c oxidase|regulation of cytochrome c oxidase activity|regulation of caa3-type cytochrome c oxidase|regulation of cbb3-type cytochrome c oxidase|regulation of cytochrome oxidase activity|regulation of warburg's respiratory enzyme activity|regulation of ferrocytochrome-c:oxygen oxidoreductase|regulation of ba3-type cytochrome c oxidase|regulation of aa3-type cytochrome c oxidase|regulation of complex IV (mitochondrial electron transport) activity|regulation of indophenolase|regulation of indophenol oxidase|regulation of NADH cytochrome c oxidase Any process that modulates the frequency, rate or extent of cytochrome-c oxidase activity. GO:1904958 positive regulation of midbrain dopaminergic neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904958 activation of midbrain DA neurogenesis|up-regulation of midbrain DA neurogenesis|up regulation of midbrain dopaminergic neuron differentiation|up regulation of DA neurogenesis from midbrain floor plate|up regulation of midbrain dopaminergic neuron production|activation of midbrain dopaminergic neuron production|activation of DA neurogenesis from midbrain floor plate|upregulation of mDA neuron differentiation|positive regulation of midbrain dopaminergic neuron production|positive regulation of DA neurogenesis from midbrain floor plate|positive regulation of midbrain DA neurogenesis|up regulation of midbrain DA neurogenesis|upregulation of midbrain dopaminergic neuron differentiation|activation of mDA neuron differentiation|up-regulation of mDA neuron differentiation|up-regulation of DA neurogenesis from midbrain floor plate|up-regulation of midbrain dopaminergic neuron production|up-regulation of midbrain dopaminergic neuron differentiation|activation of midbrain dopaminergic neuron differentiation|upregulation of midbrain DA neurogenesis|upregulation of DA neurogenesis from midbrain floor plate|upregulation of midbrain dopaminergic neuron production|positive regulation of mDA neuron differentiation|up regulation of mDA neuron differentiation Any process that activates or increases the frequency, rate or extent of midbrain dopaminergic neuron differentiation. GO:1904957 negative regulation of midbrain dopaminergic neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904957 downregulation of mDA neuron differentiation|downregulation of midbrain dopaminergic neuron production|downregulation of DA neurogenesis from midbrain floor plate|down regulation of mDA neuron differentiation|inhibition of mDA neuron differentiation|downregulation of midbrain dopaminergic neuron differentiation|down-regulation of midbrain DA neurogenesis|negative regulation of midbrain DA neurogenesis|down regulation of midbrain dopaminergic neuron differentiation|negative regulation of DA neurogenesis from midbrain floor plate|negative regulation of midbrain dopaminergic neuron production|down-regulation of midbrain dopaminergic neuron production|down-regulation of DA neurogenesis from midbrain floor plate|inhibition of midbrain dopaminergic neuron differentiation|downregulation of midbrain DA neurogenesis|inhibition of DA neurogenesis from midbrain floor plate|inhibition of midbrain dopaminergic neuron production|down regulation of midbrain DA neurogenesis|inhibition of midbrain DA neurogenesis|down-regulation of mDA neuron differentiation|negative regulation of mDA neuron differentiation|down-regulation of midbrain dopaminergic neuron differentiation|down regulation of midbrain dopaminergic neuron production|down regulation of DA neurogenesis from midbrain floor plate Any process that stops, prevents or reduces the frequency, rate or extent of midbrain dopaminergic neuron differentiation. GO:1904956 regulation of midbrain dopaminergic neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904956 regulation of midbrain dopaminergic neuron production|regulation of DA neurogenesis from midbrain floor plate|regulation of mDA neuron differentiation|regulation of midbrain DA neurogenesis Any process that modulates the frequency, rate or extent of midbrain dopaminergic neuron differentiation. GO:1904955 planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904955 Wnt receptor signalling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron production|PCP pathway involved in midbrain dopaminergic neuron differentiation|Wnt receptor signalling pathway, planar cell polarity pathway involved in DA neurogenesis from midbrain floor plate|Wnt receptor signalling pathway, planar cell polarity pathway involved in mDA neuron differentiation|Wnt receptor signaling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation|Wnt-JNK signaling pathway involved in midbrain DA neurogenesis|Wnt-PCP signaling pathway involved in DA neurogenesis from midbrain floor plate|Wnt-PCP signaling pathway involved in midbrain dopaminergic neuron production|Wnt-activated signaling pathway, planar cell polarity pathway involved in DA neurogenesis from midbrain floor plate|Wnt-activated signaling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron production|Wnt-activated signaling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation|non-canonical Wnt signaling pathway involved in midbrain DA neurogenesis|planar cell polarity pathway involved in mDA neuron differentiation|Wnt receptor signaling pathway, planar cell polarity pathway involved in DA neurogenesis from midbrain floor plate|Wnt receptor signaling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron production|non-canonical Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron production|PCP pathway involved in DA neurogenesis from midbrain floor plate|Wnt signaling pathway, planar cell polarity pathway involved in DA neurogenesis from midbrain floor plate|PCP pathway involved in midbrain dopaminergic neuron production|Wnt receptor signalling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation|Wnt signaling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron production|Wnt-PCP signaling pathway involved in mDA neuron differentiation|Wnt signaling pathway, planar cell polarity pathway involved in midbrain DA neurogenesis|PCP pathway involved in midbrain DA neurogenesis|planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation|Wnt receptor signaling pathway, planar cell polarity pathway involved in midbrain DA neurogenesis|Wnt-activated signaling pathway, planar cell polarity pathway involved in midbrain DA neurogenesis|Wnt-PCP signaling pathway involved in midbrain dopaminergic neuron differentiation|Wnt signaling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation|Wnt receptor signalling pathway, planar cell polarity pathway involved in midbrain DA neurogenesis|non-canonical Wnt-mediated midbrain DA neuron differentiation|Wnt-JNK signaling pathway involved in mDA neuron differentiation|non-canonical Wnt signaling pathway involved in mDA neuron differentiation|planar cell polarity pathway involved in midbrain DA neurogenesis|Wnt-JNK signaling pathway involved in midbrain dopaminergic neuron differentiation|Wnt-JNK signaling pathway involved in DA neurogenesis from midbrain floor plate|Wnt-JNK signaling pathway involved in midbrain dopaminergic neuron production|Wnt-PCP signaling pathway involved in midbrain DA neurogenesis|PCP pathway involved in mDA neuron differentiation|Wnt signaling pathway, planar cell polarity pathway involved in mDA neuron differentiation|non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|Wnt receptor signaling pathway, planar cell polarity pathway involved in mDA neuron differentiation|planar cell polarity pathway involved in midbrain dopaminergic neuron production|planar cell polarity pathway involved in DA neurogenesis from midbrain floor plate|Wnt-activated signaling pathway, planar cell polarity pathway involved in mDA neuron differentiation Any Wnt signaling pathway, planar cell polarity pathway that is involved in midbrain dopaminergic neuron differentiation. GO:1904954 canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904954 canonical Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|canonical Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|canonical Wnt receptor signaling pathway involved in mDA neuron differentiation|Wnt receptor signaling pathway through beta-catenin involved in midbrain DA neurogenesis|frizzled-1 receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|canonical Wnt-mediated midbrain DA neuron differentiation|canonical Wnt signaling pathway involved in mDA neuron differentiation|canonical Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|Wnt receptor signaling pathway via beta-catenin involved in mDA neuron differentiation|frizzled-1 receptor signaling pathway involved in midbrain DA neurogenesis|Wnt receptor signalling pathway through beta-catenin involved in mDA neuron differentiation|canonical Wnt-activated signaling pathway involved in mDA neuron differentiation|Wnt receptor signaling pathway via beta-catenin involved in midbrain dopaminergic neuron differentiation|Wnt receptor signaling pathway through beta-catenin involved in DA neurogenesis from midbrain floor plate|Wnt receptor signaling pathway through beta-catenin involved in midbrain dopaminergic neuron production|Wnt receptor signaling pathway through beta-catenin involved in mDA neuron differentiation|canonical Wnt receptor signaling pathway involved in midbrain DA neurogenesis|Wnt receptor signalling pathway through beta-catenin involved in midbrain dopaminergic neuron differentiation|canonical Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|Wnt receptor signalling pathway through beta-catenin involved in midbrain dopaminergic neuron production|canonical Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|canonical Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|Wnt receptor signalling pathway through beta-catenin involved in DA neurogenesis from midbrain floor plate|canonical Wnt signaling pathway involved in midbrain DA neurogenesis|Wnt receptor signaling pathway through beta-catenin involved in midbrain dopaminergic neuron differentiation|Wnt receptor signaling pathway via beta-catenin involved in DA neurogenesis from midbrain floor plate|Wnt receptor signaling pathway via beta-catenin involved in midbrain DA neurogenesis|Wnt receptor signaling pathway via beta-catenin involved in midbrain dopaminergic neuron production|canonical Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|canonical Wnt signaling pathway involved in midbrain dopaminergic neuron production|frizzled-1 receptor signaling pathway involved in midbrain dopaminergic neuron production|canonical Wnt-activated signaling pathway involved in midbrain DA neurogenesis|frizzled-1 receptor signaling pathway involved in mDA neuron differentiation|Wnt receptor signalling pathway through beta-catenin involved in midbrain DA neurogenesis|frizzled-1 receptor signaling pathway involved in DA neurogenesis from midbrain floor plate Any canonical Wnt signaling pathway that is involved in midbrain dopaminergic neuron differentiation. GO:0047139 glutathione-homocystine transhydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047139 MetaCyc:1.8.4.1-RXN|RHEA:11464|EC:1.8.4.1 glutathione:homocystine oxidoreductase activity Catalysis of the reaction: homocystine + 2 reduced glutathione = oxidized glutathione + 2 homocysteine. GO:0047138 obsolete aquacobalamin reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047138 MetaCyc:AQUACOBALAMIN-REDUCTASE-RXN|EC:1.16.1.3|RHEA:24472 NADH:cob(III)alamin oxidoreductase activity|NADH-linked aquacobalamin reductase activity|NADH2:cob(III)alamin oxidoreductase activity|aquocobalamin reductase activity|vitamin B12a reductase activity|B(12a) reductase activity|cob(II)alamin:NAD+ oxidoreductase activity|vitamin B(12a) reductase activity|B12a reductase activity OBSOLETE. Catalysis of the reaction: 2 cob(II)alamin + NAD+ = 2 aquacob(III)alamin + NADH + H+. GO:1904953 Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904953 Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|Wnt signaling pathway involved in midbrain DA neurogenesis|frizzled signaling pathway involved in mDA neuron differentiation|Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|Wnt receptor signaling pathway involved in midbrain DA neurogenesis|Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|Wingless signalling pathway involved in midbrain DA neurogenesis|Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|Wg signaling pathway involved in mDA neuron differentiation|Wingless signaling pathway involved in midbrain dopaminergic neuron production|Wingless signalling pathway involved in midbrain dopaminergic neuron production|Wg signalling pathway involved in mDA neuron differentiation|Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|Wingless signaling pathway involved in midbrain DA neurogenesis|Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|Wnt receptor signalling pathway involved in midbrain DA neurogenesis|Wnt-activated signaling pathway involved in midbrain DA neurogenesis|frizzled signalling pathway involved in mDA neuron differentiation|Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|Wnt signaling pathway involved in midbrain dopaminergic neuron production|Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|Wnt signaling pathway involved in mDA neuron differentiation|frizzled signalling pathway involved in midbrain dopaminergic neuron production|frizzled signaling pathway involved in midbrain DA neurogenesis|frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|Wnt receptor signaling pathway involved in mDA neuron differentiation|Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|Wingless signalling pathway involved in mDA neuron differentiation|Wg signaling pathway involved in midbrain DA neurogenesis|Wg signalling pathway involved in midbrain dopaminergic neuron production|Wingless signaling pathway involved in mDA neuron differentiation|Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|Wnt-mediated midbrain DA neuron differentiation|Wg signalling pathway involved in midbrain DA neurogenesis|Wg signaling pathway involved in midbrain dopaminergic neuron production|Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|Wnt receptor signalling pathway involved in mDA neuron differentiation|Wnt-activated signaling pathway involved in mDA neuron differentiation|frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|frizzled signaling pathway involved in midbrain dopaminergic neuron production|frizzled signalling pathway involved in midbrain DA neurogenesis Any Wnt signaling pathway that is involved in midbrain dopaminergic neuron differentiation. GO:1904952 hydroxycinnamic acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904952 The directed movement of a hydroxycinnamic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0047137 N-hydroxy-2-acetamidofluorene reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047137 EC:1.7.1.12|MetaCyc:1.7.1.12-RXN NAD(P)H2:N-hydroxy-2-acetamidofluorene N-oxidoreductase activity|NAD(P)H:N-hydroxy-2-acetamidofluorene N-oxidoreductase activity|2-acetamidofluorene:NAD(P)+ oxidoreductase activity|N-hydroxy-2-acetylaminofluorene reductase activity Catalysis of the reaction: 2-acetamidofluorene + NAD(P)+ + H2O = N-hydroxy-2-acetamidofluorene + NAD(P)H + H+. GO:1904951 positive regulation of establishment of protein localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904951 positive regulation of protein positioning|up regulation of establishment of protein localization|activation of establishment of protein localization|up-regulation of protein recruitment|up-regulation of establishment of protein localisation|up-regulation of protein positioning|up-regulation of establishment of protein localization|upregulation of protein recruitment|upregulation of establishment of protein localisation|upregulation of protein positioning|upregulation of establishment of protein localization|up regulation of protein recruitment|activation of protein recruitment|positive regulation of protein recruitment|up regulation of establishment of protein localisation|up regulation of protein positioning|activation of establishment of protein localisation|positive regulation of establishment of protein localisation|activation of protein positioning Any process that activates or increases the frequency, rate or extent of establishment of protein localization. GO:0047136 4-(dimethylamino)phenylazoxybenzene reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047136 EC:1.7.1.11|KEGG_REACTION:R04303|RHEA:19789|MetaCyc:1.6.6.12-RXN 4-(dimethylamino)phenylazobenzene:NADP+ oxidoreductase activity|NADPH:4-(dimethylamino)phenylazoxybenzene oxidoreductase activity|NADPH2:4-(dimethylamino)phenylazoxybenzene oxidoreductase activity|N,N-dimethyl-p-aminoazobenzene oxide reductase activity|NADPH-dependent DMAB N-oxide reductase activity|dimethylaminoazobenzene N-oxide reductase activity Catalysis of the reaction: 4-(dimethylamino)azobenzene + H(2)O + NADP(+) = 4-(dimethylamino)phenylazoxybenzene + H(+) + NADPH. GO:1904950 negative regulation of establishment of protein localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904950 down-regulation of protein recruitment|negative regulation of protein recruitment|downregulation of establishment of protein localization|down-regulation of establishment of protein localisation|negative regulation of establishment of protein localisation|negative regulation of protein positioning|down-regulation of protein positioning|inhibition of protein recruitment|inhibition of establishment of protein localisation|down-regulation of establishment of protein localization|inhibition of protein positioning|inhibition of establishment of protein localization|down regulation of protein recruitment|down regulation of establishment of protein localisation|down regulation of protein positioning|downregulation of protein recruitment|downregulation of establishment of protein localisation|downregulation of protein positioning|down regulation of establishment of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization. GO:0047135 bis-gamma-glutamylcystine reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047135 MetaCyc:1.6.4.9-RXN|EC:1.8.1.13|KEGG_REACTION:R02742|RHEA:11980 bis-g-glutamylcystine reductase (NADPH) activity|bis-gamma-glutamylcystine reductase (NADPH) activity|NADPH2:bis-gamma-glutamylcysteine oxidoreductase activity|gamma-glutamylcysteine:NADP+ oxidoreductase activity|NADPH:bis-gamma-glutamylcysteine oxidoreductase activity|Bis-gamma-glutamylcystine reductase (NADPH) Catalysis of the reaction: 2 L-gamma-glutamyl-L-cysteine + NADP(+) = bis-gamma-glutamylcystine + H(+) + NADPH. GO:0047134 protein-disulfide reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047134 MetaCyc:1.6.4.4-RXN|EC:1.8.1.8 insulin-glutathione transhydrogenase activity|disulfide reductase activity|protein disulphide reductase activity|protein disulfide reductase activity|protein-dithiol:NAD(P)+ oxidoreductase activity|NAD(P)H2:protein-disulfide oxidoreductase activity|protein-disulphide reductase activity|NAD(P)H:protein-disulfide oxidoreductase activity|protein-disulfide reductase (NAD(P)H) activity Catalysis of the reaction: protein-dithiol + NAD(P)+ = protein-disulfide + NAD(P)H + H+. GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047144 Reactome:R-HSA-1482635|Reactome:R-HSA-1482626|Reactome:R-HSA-1482646|Reactome:R-HSA-1482533|MetaCyc:2-ACYL2.3.1.15-RXN|EC:2.3.1.52|Reactome:R-HSA-1482546|RHEA:14233|Reactome:R-HSA-1482691 2-acylglycerophosphate acyltransferase activity|acyl-CoA:2-acyl-sn-glycerol 3-phosphate O-acyltransferase activity Catalysis of the reaction: 2-acyl-sn-glycerol 3-phosphate + acyl-CoA = L-phosphatidate + CoA. GO:0047143 chlorate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047143 EC:1.97.1.1|MetaCyc:1.97.1.1-RXN|UM-BBD_reactionID:r0981|RHEA:16349|KEGG_REACTION:R03575 chlorite:acceptor oxidoreductase activity|chlorate reductase C Catalysis of the reaction: AH(2) + chlorate = A + chlorite + H(2)O + H(+). GO:0047142 enzyme-thiol transhydrogenase (glutathione-disulfide) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047142 MetaCyc:1.8.4.7-RXN|EC:1.8.4.7 xanthine-dehydrogenase:oxidized-glutathione S-oxidoreductase activity|enzyme-thiol transhydrogenase (glutathione-disulphide) activity|xanthine-dehydrogenase:glutathione-disulfide S-oxidoreductase activity|glutathione-dependent thiol:disulfide oxidoreductase activity|thiol:disulfide oxidoreductase activity|[xanthine-dehydrogenase]:oxidized-glutathione S-oxidoreductase activity|thiol:disulphide oxidoreductase activity|enzyme-thiol transhydrogenase (oxidized-glutathione) activity Catalysis of the reaction: oxidized glutathione + [xanthine dehydrogenase] = reduced glutathione + xanthine-oxidase. GO:0047141 glutathione-cystine transhydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047141 MetaCyc:1.8.4.4-RXN|RHEA:12613|EC:1.8.4.4 NADPH-dependent GSH-cystine transhydrogenase|glutathione:cystine oxidoreductase|GSH-cystine transhydrogenase Catalysis of the reaction: cystine + 2 reduced glutathione = oxidized glutathione + 2 L-cysteine. GO:0047140 glutathione-CoA-glutathione transhydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047140 MetaCyc:1.8.4.3-RXN|RHEA:13125|EC:1.8.4.3 coenzyme A:oxidized-glutathione oxidoreductase activity|glutathione:coenzyme A-glutathione transhydrogenase activity|coenzyme A:glutathione-disulfide oxidoreductase activity|glutathione-coenzyme A glutathione disulfide transhydrogenase activity|glutathione coenzyme A-glutathione transhydrogenase activity|CoA:glutathione-disulfide oxidoreductase activity Catalysis of the reaction: oxidized glutathione + CoA = reduced glutathione + CoA-glutathione. GO:1904969 slow muscle cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904969 slow-twitch muscle cell migration The orderly movement of a slow muscle cell from one site to another. GO:1904968 positive regulation of monopolar spindle attachment to meiosis I kinetochore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904968 up-regulation of sister kinetochore mono-orientation|activation of attachment of spindle microtubules to kinetochore during meiosis I|up-regulation of monopolar attachment|upregulation of attachment of spindle microtubules to kinetochore involved in meiosis I|activation of monopolar attachment|up-regulation of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation|positive regulation of attachment of spindle microtubules to kinetochore during meiosis I|upregulation of sister kinetochore mono-orientation|up regulation of attachment of spindle microtubules to kinetochore during meiosis I|positive regulation of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation|up regulation of attachment of spindle microtubules to kinetochore involved in meiosis I|positive regulation of monopolar attachment|positive regulation of attachment of spindle microtubules to kinetochore involved in meiosis I|activation of attachment of spindle microtubules to kinetochore involved in meiosis I|upregulation of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation|up regulation of monopolar attachment|up regulation of sister kinetochore mono-orientation|upregulation of attachment of spindle microtubules to kinetochore during meiosis I|activation of sister kinetochore mono-orientation|positive regulation of sister kinetochore mono-orientation|up regulation of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation|up-regulation of attachment of spindle microtubules to kinetochore involved in meiosis I|upregulation of monopolar attachment|activation of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation|up-regulation of attachment of spindle microtubules to kinetochore during meiosis I Any process that activates or increases the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation. GO:1904967 regulation of monopolar spindle attachment to meiosis I kinetochore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904967 regulation of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation|regulation of attachment of spindle microtubules to kinetochore involved in meiosis I|regulation of attachment of spindle microtubules to kinetochore during meiosis I|regulation of sister kinetochore mono-orientation|correction of merotelic kinetochore attachment, meiosis I|regulation of monopolar attachment|repair of merotelic kinetochore attachment defect, meiosis I Any process that modulates the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation. GO:1904966 positive regulation of vitamin E biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904966 activation of vitamin E synthesis|positive regulation of vitamin E synthesis|up regulation of vitamin E formation|positive regulation of vitamin E biosynthesis|activation of vitamin E formation|positive regulation of vitamin E formation|up regulation of vitamin E biosynthesis|up regulation of vitamin E biosynthetic process|up regulation of tocopherol biosynthetic process|upregulation of alpha-tocopherol biosynthetic process|upregulation of alpha-tocopherol biosynthesis|up regulation of tocopherol biosynthesis|up-regulation of vitamin E anabolism|positive regulation of tocopherol biosynthesis|positive regulation of tocopherol biosynthetic process|activation of tocopherol biosynthesis|activation of tocopherol biosynthetic process|up-regulation of vitamin E synthesis|upregulation of vitamin E biosynthesis|up-regulation of vitamin E formation|upregulation of vitamin E biosynthetic process|upregulation of vitamin E anabolism|up regulation of alpha-tocopherol biosynthesis|up regulation of alpha-tocopherol biosynthetic process|positive regulation of alpha-tocopherol biosynthetic process|positive regulation of alpha-tocopherol biosynthesis|up-regulation of tocopherol biosynthesis|up-regulation of tocopherol biosynthetic process|upregulation of vitamin E synthesis|up-regulation of vitamin E biosynthetic process|upregulation of vitamin E formation|activation of alpha-tocopherol biosynthetic process|up-regulation of vitamin E biosynthesis|activation of alpha-tocopherol biosynthesis|activation of vitamin E biosynthetic process|activation of vitamin E biosynthesis|up regulation of vitamin E anabolism|activation of vitamin E anabolism|upregulation of tocopherol biosynthesis|positive regulation of vitamin E anabolism|upregulation of tocopherol biosynthetic process|up-regulation of alpha-tocopherol biosynthesis|up-regulation of alpha-tocopherol biosynthetic process|up regulation of vitamin E synthesis Any process that activates or increases the frequency, rate or extent of vitamin E biosynthetic process. GO:1904965 regulation of vitamin E biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904965 regulation of tocopherol biosynthesis|regulation of tocopherol biosynthetic process|regulation of vitamin E biosynthesis|regulation of alpha-tocopherol biosynthesis|regulation of alpha-tocopherol biosynthetic process|regulation of vitamin E anabolism|regulation of vitamin E synthesis|regulation of vitamin E formation Any process that modulates the frequency, rate or extent of vitamin E biosynthetic process. GO:0047149 thetin-homocysteine S-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047149 MetaCyc:2.1.1.3-RXN|KEGG_REACTION:R04153|EC:2.1.1.3|RHEA:22788 dimethylthetin-homocysteine methyltransferase activity|dimethylsulfonioacetate:L-homocysteine S-methyltransferase activity|thetin-homocysteine methylpherase activity Catalysis of the reaction: L-homocysteine + dimethylsulfonioacetate = (methylthio)acetate + L-methionine + H(+). GO:1904964 positive regulation of phytol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904964 upregulation of phytol formation|upregulation of phytol biosynthesis|upregulation of phytol biosynthetic process|up-regulation of phytol anabolism|activation of phytol anabolism|up-regulation of phytol synthesis|activation of phytol synthesis|up-regulation of phytol formation|activation of phytol formation|up regulation of phytol biosynthesis|up regulation of phytol biosynthetic process|activation of phytol biosynthesis|activation of phytol biosynthetic process|positive regulation of phytol anabolism|positive regulation of phytol biosynthesis|up regulation of phytol anabolism|positive regulation of phytol synthesis|up regulation of phytol synthesis|positive regulation of phytol formation|up regulation of phytol formation|up-regulation of phytol biosynthetic process|up-regulation of phytol biosynthesis|upregulation of phytol anabolism|upregulation of phytol synthesis Any process that activates or increases the frequency, rate or extent of phytol biosynthetic process. GO:0047148 methylamine-glutamate N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047148 MetaCyc:2.1.1.21-RXN|EC:2.1.1.21|RHEA:15837|KEGG_REACTION:R01586 methylamine:L-glutamate N-methyltransferase activity|N-methylglutamate synthase activity|methylamine-glutamate methyltransferase activity Catalysis of the reaction: L-glutamate + methylammonium = N-methyl-L-glutamate + NH(4)(+). GO:1904963 regulation of phytol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904963 regulation of phytol biosynthesis|regulation of phytol anabolism|regulation of phytol synthesis|regulation of phytol formation Any process that modulates the frequency, rate or extent of phytol biosynthetic process. GO:0047147 trimethylsulfonium-tetrahydrofolate N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047147 EC:2.1.1.19|MetaCyc:2.1.1.19-RXN|KEGG_REACTION:R02573|RHEA:13693 trimethylsulfonium-tetrahydrofolate methyltransferase activity|trimethylsulphonium-tetrahydrofolate N-methyltransferase activity|trimethylsulfonium:tetrahydrofolate N-methyltransferase activity Catalysis of the reaction: (6S)-5,6,7,8-tetrahydrofolate + trimethylsulfonium = (6S)-5-methyl-5,6,7,8-tetrahydrofolate + dimethyl sulfide + H(+). GO:1904962 plastid to vacuole vesicle-mediated transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904962 plastid to vacuolar carboxypeptidase Y vesicle-mediated transport The vesicle-mediated and directed movement of substances from plastid to vacuole. GO:0047146 sterigmatocystin 7-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047146 RHEA:15561|MetaCyc:2.1.1.110-RXN|EC:2.1.1.110 sterigmatocystin methyltransferase activity|sterigmatocystin 8-O-methyltransferase activity|S-adenosyl-L-methionine:sterigmatocystin 7-O-methyltransferase activity|S-adenosyl-L-methionine:sterigmatocystin 8-O-methyltransferase activity|O-methyltransferase II activity Catalysis of the reaction: sterigmatocystin + S-adenosyl-L-methionine = 7-O-methylsterigmatocystin + S-adenosyl-homocysteine. GO:1904961 quiescent center organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904961 quiescent center structural organization The process that contributes to the act of creating the structural organization of the quiescent center. This process pertains to the physical shaping of a rudimentary structure. GO:1904960 positive regulation of cytochrome-c oxidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904960 activation of aa3-type cytochrome c oxidase|up regulation of NADH cytochrome c oxidase|up-regulation of cytochrome c oxidase activity|up-regulation of ferrocytochrome c oxidase|activation of NADH cytochrome c oxidase|activation of cytochrome a3 activity|positive regulation of NADH cytochrome c oxidase|up-regulation of cytochrome oxidase activity|up-regulation of warburg's respiratory enzyme activity|activation of indophenolase|up-regulation of complex IV (mitochondrial electron transport) activity|up-regulation of ferrocytochrome-c:oxygen oxidoreductase|up-regulation of ba3-type cytochrome c oxidase|activation of caa3-type cytochrome c oxidase|activation of cbb3-type cytochrome c oxidase|up-regulation of aa3-type cytochrome c oxidase|upregulation of cytochrome aa3 activity|up-regulation of indophenol oxidase|positive regulation of cytochrome a3 activity|up regulation of cytochrome-c oxidase activity|activation of cytochrome-c oxidase activity|positive regulation of cbb3-type cytochrome c oxidase|up-regulation of indophenolase|positive regulation of caa3-type cytochrome c oxidase|activation of complex IV (mitochondrial electron transport) activity|up regulation of cytochrome a3 activity|upregulation of ferrocytochrome c oxidase|upregulation of cytochrome c oxidase activity|up regulation of caa3-type cytochrome c oxidase|up regulation of cbb3-type cytochrome c oxidase|upregulation of cytochrome oxidase activity|upregulation of warburg's respiratory enzyme activity|upregulation of ferrocytochrome-c:oxygen oxidoreductase|up-regulation of NADH cytochrome c oxidase|activation of indophenol oxidase|upregulation of ba3-type cytochrome c oxidase|positive regulation of complex IV (mitochondrial electron transport) activity|upregulation of aa3-type cytochrome c oxidase|up regulation of cytochrome aa3 activity|up regulation of complex IV (mitochondrial electron transport) activity|positive regulation of indophenol oxidase|positive regulation of cytochrome aa3 activity|upregulation of indophenolase|upregulation of cytochrome a3 activity|up regulation of ferrocytochrome c oxidase|up-regulation of cytochrome-c oxidase activity|up regulation of indophenol oxidase|up regulation of cytochrome c oxidase activity|upregulation of caa3-type cytochrome c oxidase|upregulation of cbb3-type cytochrome c oxidase|up regulation of cytochrome oxidase activity|up regulation of warburg's respiratory enzyme activity|positive regulation of cytochrome c oxidase activity|positive regulation of ferrocytochrome c oxidase|upregulation of NADH cytochrome c oxidase|activation of cytochrome c oxidase activity|up regulation of ba3-type cytochrome c oxidase|up regulation of ferrocytochrome-c:oxygen oxidoreductase|activation of cytochrome aa3 activity|positive regulation of warburg's respiratory enzyme activity|positive regulation of cytochrome oxidase activity|up regulation of aa3-type cytochrome c oxidase|positive regulation of ba3-type cytochrome c oxidase|positive regulation of ferrocytochrome-c:oxygen oxidoreductase|upregulation of complex IV (mitochondrial electron transport) activity|positive regulation of aa3-type cytochrome c oxidase|activation of ferrocytochrome c oxidase|up-regulation of cytochrome a3 activity|up regulation of indophenolase|activation of cytochrome oxidase activity|up-regulation of cytochrome aa3 activity|upregulation of cytochrome-c oxidase activity|activation of warburg's respiratory enzyme activity|activation of ferrocytochrome-c:oxygen oxidoreductase|upregulation of indophenol oxidase|up-regulation of cbb3-type cytochrome c oxidase|positive regulation of indophenolase|activation of ba3-type cytochrome c oxidase|up-regulation of caa3-type cytochrome c oxidase Any process that activates or increases the frequency, rate or extent of cytochrome-c oxidase activity. GO:0047145 demethylsterigmatocystin 6-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047145 RHEA:11504|MetaCyc:2.1.1.109-RXN|EC:2.1.1.109 O-methyltransferase I|demethylsterigmatocystin methyltransferase activity|S-adenosyl-L-methionine:6-demethylsterigmatocystin 6-O-methyltransferase activity Catalysis of the reaction: 6-demethylsterigmatocystin + S-adenosyl-L-methionine = sterigmatocystin + S-adenosyl-homocysteine. GO:1904970 brush border assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904970 brush border formation The aggregation, arrangement and bonding together of adjacent microvilli through the formation of Ca(2+)-dependent adhesion links between them, forming a brush border. GO:0072111 cell proliferation involved in kidney development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072111 The multiplication or reproduction of cells, resulting in the expansion of the population in the kidney. GO:0047155 3-hydroxymethylcephem carbamoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047155 MetaCyc:2.1.3.7-RXN|EC:2.1.3.7 3'-hydroxymethylcephem-O-carbamoyltransferase activity|carbamoyl-phosphate:3-hydroxymethylceph-3-em-4-carboxylate carbamoyltransferase activity Catalysis of the reaction: a 3-hydroxymethylceph-3-em-4-carboxylate + carbamoyl-phosphate = phosphate + a 3-carbamoyloxymethylcephem. GO:0047154 methylmalonyl-CoA carboxytransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047154 RHEA:20764|MetaCyc:2.1.3.1-RXN|EC:2.1.3.1|UM-BBD_reactionID:r0923 (S)-methylmalonyl-CoA:pyruvate carboxytransferase activity|methylmalonyl-CoA transcarboxylase activity|(S)-2-methyl-3-oxopropanoyl-CoA:pyruvate carboxyltransferase activity|(S)-methylmalonyl-CoA:pyruvate carboxyltransferase activity|methylmalonyl-CoA carboxyltransferase activity|(S)-2-methyl-3-oxopropanoyl-CoA:pyruvate|methylmalonyl coenzyme A carboxyltransferase activity|transcarboxylase activity|oxalacetic transcarboxylase activity Catalysis of the reaction: pyruvate + D-methylmalonyl-CoA = oxaloacetic acid + propionyl-CoA. GO:0072110 glomerular mesangial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072110 The multiplication or reproduction of glomerular mesangial cells, resulting in the expansion of the population. GO:0047153 deoxycytidylate 5-hydroxymethyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047153 MetaCyc:2.1.2.8-RXN|EC:2.1.2.8|RHEA:11280|KEGG_REACTION:R01669 5,10-methylenetetrahydrofolate:deoxycytidylate 5-hydroxymethyltransferase activity|deoxycytidylate hydroxymethyltransferase activity|deoxycytidylic hydroxymethylase activity|deoxyCMP hydroxymethylase activity|deoxycytidylate hydroxymethylase activity|d-cytidine 5'-monophosphate hydroxymethylase activity|dCMP hydroxymethylase activity Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dCMP + H(2)O = (6S)-5,6,7,8-tetrahydrofolate + 5-hydroxymethyldeoxycytidylate. GO:0047152 methanol-5-hydroxybenzimidazolylcobamide Co-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047152 RHEA:21344|EC:2.1.1.90|MetaCyc:2.1.1.90-RXN methanol:corrinoid methyltransferase activity|methyltransferase 1|MT1|methanol-corrinoid protein Co-methyltransferase|MtaB|methanol cobalamin methyltransferase activity|methanol:5-hydroxybenzimidazolylcobamide Co-methyltransferase activity|MT 1|methanol:5-hydroxybenzimidazolylcobamide methyltransferase activity Catalysis of the reaction: 5-hydroxybenzimidazolylcobamide + methanol = H2O + Co-methyl-Co-5-hydroxybenzimidazolylcob(I)amide. GO:0047151 methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH2-oxidizing) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047151 EC:2.1.1.74|RHEA:16873|MetaCyc:2.1.1.74-RXN|KEGG_REACTION:R03704 5,10-methylenetetrahydrofolate:tRNA-UPsiC (uracil-5-)-methyl-transferase activity|folate-dependent ribothymidyl synthase activity|methylenetetrahydrofolate-transfer ribonucleate uracil 5-methyltransferase activity|5,10-methylenetetrahydrofolate:tRNA (uracil-5-)-methyltransferase activity|methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH-oxidizing) activity Catalysis of the reaction: 5,10-methylenetetrahydrofolate + tRNA containing uridine at position 54 + FADH + H+ = tetrahydrofolate + tRNA containing ribothymidine at position 54 + FAD+. GO:0047150 betaine-homocysteine S-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047150 KEGG_REACTION:R02821|RHEA:22336|MetaCyc:2.1.1.5-RXN|EC:2.1.1.5|Reactome:R-HSA-1614654 betaine-homocysteine transmethylase activity|trimethylammonioacetate:L-homocysteine S-methyltransferase activity|betaine-homocysteine methyltransferase activity Catalysis of the reaction: L-homocysteine + betaine = N,N-dimethylglycine + L-methionine. GO:1904979 negative regulation of endosome organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904979 down regulation of endosome organisation|downregulation of endosome organisation|down regulation of endosome organization|negative regulation of endosome organization and biogenesis|down-regulation of endosome organization and biogenesis|downregulation of endosome organization|down-regulation of endosome organisation|negative regulation of endosome organisation|downregulation of endosome organization and biogenesis|inhibition of endosome organisation|down-regulation of endosome organization|down regulation of endosome organization and biogenesis|inhibition of endosome organization|inhibition of endosome organization and biogenesis Any process that stops, prevents or reduces the frequency, rate or extent of endosome organization. GO:1904978 regulation of endosome organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904978 regulation of endosome organisation|regulation of endosome organization and biogenesis Any process that modulates the frequency, rate or extent of endosome organization. GO:1904977 lymphatic endothelial cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904977 The orderly movement of a lymphatic endothelial cell from one site to another in the wall of a lymphatic vessel. GO:1904976 cellular response to bleomycin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904976 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bleomycin stimulus. GO:1904975 response to bleomycin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904975 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bleomycin stimulus. GO:1904974 heparanase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1904974 HEPS complex A protein complex which is capable of heparanase activity. GO:0047159 1-alkenylglycerophosphocholine O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047159 EC:2.3.1.25|RHEA:10344|MetaCyc:2.3.1.104-RXN acyl-CoA:1-alkenylglycerophosphocholine O-acyltransferase activity Catalysis of the reaction: 1-alkenylglycerophosphocholine + acyl-CoA = 1-alkenyl-2-acylglycerophosphocholine + CoA. GO:0047158 sinapoylglucose-sinapoylglucose O-sinapoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047158 RHEA:22664|MetaCyc:2.3.1.103-RXN|KEGG_REACTION:R00063|EC:2.3.1.103 1-(hydroxycinnamoyl)-glucose:1-(hydroxycinnamoyl)-glucose hydroxycinnamoyltransferase activity|1-O-(4-hydroxy-3,5-dimethoxycinnamoyl)-beta-D-glucoside:1-O-(4-hydroxy-3,5-dimethoxycinnamoyl-beta-D-glucoside 1-O-sinapoyltransferase activity|hydroxycinnamoylglucose-hydroxycinnamoylglucose hydroxycinnamoyltransferase activity Catalysis of the reaction: 2 1-O-sinapoyl-beta-D-glucose = 1,2-di-O-sinapoyl-beta-D-glucose + D-glucose. GO:1904973 positive regulation of viral translation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904973 up-regulation of viral protein synthesis|positive regulation of viral protein biosynthesis|positive regulation of viral protein biosynthetic process|up-regulation of viral protein formation|upregulation of viral protein anabolism|up regulation of viral protein biosynthesis|up regulation of viral protein biosynthetic process|up-regulation of viral translation|upregulation of viral protein synthesis|upregulation of viral protein formation|upregulation of viral protein biosynthesis|up regulation of viral protein anabolism|upregulation of viral translation|upregulation of viral protein biosynthetic process|activation of viral protein anabolism|positive regulation of viral protein anabolism|up regulation of viral protein synthesis|activation of viral protein synthesis|positive regulation of viral protein synthesis|up regulation of viral protein formation|activation of viral protein formation|activation of viral protein biosynthetic process|up-regulation of viral protein biosynthetic process|activation of viral protein biosynthesis|up-regulation of viral protein biosynthesis|positive regulation of viral protein formation|up regulation of viral translation|activation of viral translation|up-regulation of viral protein anabolism Any process that activates or increases the frequency, rate or extent of viral translation. GO:1904972 negative regulation of viral translation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904972 down-regulation of viral protein biosynthetic process|negative regulation of viral protein biosynthetic process|down-regulation of viral translation|down-regulation of viral protein biosynthesis|negative regulation of viral protein biosynthesis|inhibition of viral protein synthesis|inhibition of viral protein formation|inhibition of viral translation|down regulation of viral protein anabolism|downregulation of viral protein biosynthetic process|downregulation of viral protein biosynthesis|down regulation of viral protein synthesis|downregulation of viral protein anabolism|down regulation of viral protein biosynthesis|down regulation of viral protein biosynthetic process|inhibition of viral protein biosynthetic process|inhibition of viral protein biosynthesis|down regulation of viral protein formation|downregulation of viral protein synthesis|down regulation of viral translation|downregulation of viral protein formation|negative regulation of viral protein anabolism|down-regulation of viral protein anabolism|downregulation of viral translation|negative regulation of viral protein synthesis|down-regulation of viral protein synthesis|negative regulation of viral protein formation|down-regulation of viral protein formation|inhibition of viral protein anabolism Any process that stops, prevents or reduces the frequency, rate or extent of viral translation. GO:0047157 myelin-proteolipid O-palmitoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047157 RHEA:14869|MetaCyc:2.3.1.100-RXN|EC:2.3.1.100 [myelin-proteolipid] O-palmitoyltransferase activity|acyl-protein synthase activity|palmitoyl-CoA:[myelin-proteolipid] O-palmitoyltransferase activity|myelin PLP acyltransferase activity Catalysis of the reaction: [myelin proteolipid] + palmityl-CoA = [myelin proteolipid] O-palmitoylprotein + CoA. GO:0047156 acetoin-ribose-5-phosphate transaldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047156 RHEA:21504|KEGG_REACTION:R02345|MetaCyc:2.2.1.4-RXN|EC:2.2.1.4 3-hydroxybutan-3-one:D-ribose-5-phosphate aldehydetransferase activity|3-hydroxybutan-2-one:D-ribose-5-phosphate aldehydetransferase activity|1-deoxy-D-altro-heptulose-7-phosphate synthetase activity|1-deoxy-D-altro-heptulose-7-phosphate synthase activity Catalysis of the reaction: D-ribose 5-phosphate + acetoin = 1-deoxy-D-altro-heptulose 7-phosphate + acetaldehyde. GO:1904971 regulation of viral translation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904971 regulation of viral protein biosynthetic process|regulation of viral protein anabolism|regulation of viral protein biosynthesis|regulation of viral protein synthesis|regulation of viral protein formation Any process that modulates the frequency, rate or extent of viral translation. GO:1904981 maltose transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904981 The process in which maltose is transported across a membrane. GO:1904980 positive regulation of endosome organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904980 upregulation of endosome organization and biogenesis|up-regulation of endosome organization|upregulation of endosome organisation|up-regulation of endosome organization and biogenesis|upregulation of endosome organization|up regulation of endosome organisation|positive regulation of endosome organisation|activation of endosome organisation|activation of endosome organization and biogenesis|up regulation of endosome organization|positive regulation of endosome organization and biogenesis|up regulation of endosome organization and biogenesis|activation of endosome organization|up-regulation of endosome organisation Any process that activates or increases the frequency, rate or extent of endosome organization. GO:0072119 head kidney structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072119 head kidney structural organisation The process that contributes to the act of creating the structural organization of the head kidney. This process pertains to the physical shaping of a rudimentary structure. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney. GO:0072118 pronephros structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072118 pronephros structural organisation|pronephric kidney structural organization The process that contributes to the act of creating the structural organization of the pronephros. This process pertains to the physical shaping of a rudimentary structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life. GO:0072117 head kidney formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072117 The developmental process pertaining to the initial formation of the head kidney. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney. GO:0072116 pronephros formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072116 pronephric kidney formation The developmental process pertaining to the initial formation of the pronephros. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life. GO:0072115 head kidney morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072115 The process in which the anatomical structures of the head kidney are generated and organized. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney. GO:0072114 pronephros morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072114 pronephric kidney morphogenesis The process in which the anatomical structures of the pronephros are generated and organized. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life. SO:0001700 histone_modification biolink:SequenceFeature go-plus http://purl.obolibrary.org/obo/SO_0001700 histone modification|histone modification site Histone modification is a post translationally modified region whereby residues of the histone protein are modified by methylation, acetylation, phosphorylation, ubiquitination, sumoylation, citrullination, or ADP-ribosylation. GO:0072113 head kidney development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072113 The process whose specific outcome is the progression of the head kidney over time, from its formation to the mature structure. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney. It is analogous to the mammalian bone marrow and the primary site of definitive hematopoiesis. GO:0072112 glomerular visceral epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072112 podocyte differentiation The process in which a relatively unspecialized cell acquires specialized features of a glomerular visceral epithelial cell. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells. GO:0072100 specification of ureteric bud anterior/posterior symmetry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072100 specification of ureteric bud anterior/posterior asymmetry The establishment of the ureteric bud such that there is a similar arrangement in form and relationship of parts along its anterior/posterior axis. GO:0047166 1-alkenylglycerophosphoethanolamine O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047166 EC:2.3.1.121|RHEA:16245|MetaCyc:2.3.1.121-RXN acyl-CoA:1-alkenylglycerophosphoethanolamine O-acyltransferase activity Catalysis of the reaction: 1-alkenylglycerophosphoethanolamine + acyl-CoA = 1-alkenyl-2-acyl-glycerophosphoethanolamine + CoA. GO:0047165 flavonol-3-O-beta-glucoside O-malonyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047165 MetaCyc:2.3.1.116-RXN|RHEA:20085|EC:2.3.1.116 malonyl-CoA:flavonol-3-O-beta-D-glucoside 6''-O-malonyltransferase activity|MAT-3|flavonol 3-O-glucoside malonyltransferase activity|malonyl-coenzyme A:flavonol-3-O-glucoside malonyltransferase activity Catalysis of the reaction: flavonol 3-O-beta-D-glucoside + malonyl-CoA = malonyl-flavonol 3-O-beta-D-glucoside + CoA. GO:0047164 isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047164 MetaCyc:2.3.1.115-RXN|EC:2.3.1.115|RHEA:15581 flavone/flavonol 7-O-beta-D-glucoside malonyltransferase activity|malonyl-CoA:flavone/flavonol 7-O-glucoside malonyltransferase activity|flavone (flavonol) 7-O-glycoside malonyltransferase activity|malonyl-coenzyme A:flavone/flavonol-7-O-glycoside malonyltransferase activity|MAT-7|malonyl-coenzyme A:isoflavone 7-O-glucoside-6''-malonyltransferase activity|malonyl-CoA:isoflavone-7-O-beta-D-glucoside 6''-O-malonyltransferase activity Catalysis of the reaction: biochanin-A + malonyl-CoA = 6'-malonyl-biochanin A + CoA. GO:0047163 3,4-dichloroaniline N-malonyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047163 MetaCyc:2.3.1.114-RXN|EC:2.3.1.114|RHEA:21060|KEGG_REACTION:R04050 malonyl-CoA:3,4-dichloroaniline N-malonyltransferase activity Catalysis of the reaction: 3,4-dichloroaniline + malonyl-CoA = N-(3,4-dichlorophenyl)malonamate + CoA. GO:0047162 17-O-deacetylvindoline O-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047162 MetaCyc:2.3.1.107-RXN|EC:2.3.1.107|RHEA:24496|KEGG_REACTION:R03230 acetyl-CoA:deacetylvindoline 4-O-acetyltransferase activity|DAT activity|acetylcoenzyme A:deacetylvindoline 4-O-acetyltransferase activity|deacetylvindoline acetyltransferase activity|deacetylvindoline O-acetyltransferase activity|17-O-deacetylvindoline-17-O-acetyltransferase activity|acetyl-CoA:17-O-deacetylvindoline 17-O-acetyltransferase activity|acetylcoenzyme A-deacetylvindoline 4-O-acetyltransferase activity|acetyl-CoA-17-O-deacetylvindoline 17-O-acetyltransferase activity|acetylcoenzyme A:deacetylvindoline O-acetyltransferase activity Catalysis of the reaction: (1R,9R,10S,11R,12R,19R)-12-ethyl-10,11-dihydroxy-5-methoxy-10-(methoxycarbonyl)-8-methyl-8,16-diazapentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]nonadeca-2(7),3,5,13-tetraen-16-ium + acetyl-CoA = (1R,9R,10S,11R,12R,19R)-11-(acetyloxy)-12-ethyl-10-hydroxy-5-methoxy-10-(methoxycarbonyl)-8-methyl-8,16-diazapentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]nonadeca-2(7),3,5,13-tetraen-16-ium + CoA. GO:0047161 tartronate O-hydroxycinnamoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047161 KEGG_REACTION:R03965|RHEA:10952|MetaCyc:2.3.1.106-RXN|EC:2.3.1.106 tartronate sinapoyltransferase activity|sinapoyl-CoA:2-hydroxymalonate O-(hydroxycinnamoyl)transferase activity|hydroxycinnamoyl-coenzyme-A:tartronate hydroxycinnamoyltransferase activity Catalysis of the reaction: hydroxymalonate + sinapoyl-CoA = CoA + sinapoyltartronate. GO:0047160 alkylglycerophosphate 2-O-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047160 MetaCyc:2.3.1.105-RXN|KEGG_REACTION:R03455|RHEA:18557|EC:2.3.1.105 acetyl-CoA:1-alkyl-sn-glycero-3-phosphate 2-O-acetyltransferase activity|alkyllyso-GP:acetyl-CoA acetyltransferase activity Catalysis of the reaction: 1-alkyl-sn-glycerol 3-phosphate + acetyl-CoA = 1-alkyl-2-acetyl-sn-glycerol 3-phosphate + CoA. GO:1904989 positive regulation of endothelial cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904989 upregulation of endothelial cell activation|up regulation of endothelial cell activation|activation of endothelial cell activation|up-regulation of endothelial cell activation Any process that activates or increases the frequency, rate or extent of endothelial cell activation. GO:1904988 negative regulation of endothelial cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904988 down regulation of endothelial cell activation|downregulation of endothelial cell activation|down-regulation of endothelial cell activation|inhibition of endothelial cell activation Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell activation. GO:1904987 regulation of endothelial cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904987 Any process that modulates the frequency, rate or extent of endothelial cell activation. GO:1904986 positive regulation of quinolinate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904986 upregulation of quinolinate synthesis|up-regulation of quinolinate biosynthetic process|upregulation of quinolinate formation|up-regulation of quinolinate biosynthesis|activation of quinolinate biosynthetic process|activation of quinolinate biosynthesis|up regulation of quinolinate anabolism|positive regulation of quinolinate anabolism|activation of quinolinate anabolism|up regulation of quinolinate synthesis|positive regulation of quinolinate synthesis|activation of quinolinate synthesis|up regulation of quinolinate formation|positive regulation of quinolinate biosynthesis|positive regulation of quinolinate formation|activation of quinolinate formation|up regulation of quinolinate biosynthesis|up regulation of quinolinate biosynthetic process|up-regulation of quinolinate anabolism|up-regulation of quinolinate synthesis|upregulation of quinolinate biosynthesis|upregulation of quinolinate biosynthetic process|up-regulation of quinolinate formation|upregulation of quinolinate anabolism Any process that activates or increases the frequency, rate or extent of quinolinate biosynthetic process. GO:1904985 negative regulation of quinolinate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904985 down regulation of quinolinate anabolism|downregulation of quinolinate anabolism|down regulation of quinolinate synthesis|down regulation of quinolinate formation|downregulation of quinolinate synthesis|down-regulation of quinolinate biosynthesis|down-regulation of quinolinate biosynthetic process|negative regulation of quinolinate biosynthesis|downregulation of quinolinate formation|down-regulation of quinolinate anabolism|negative regulation of quinolinate anabolism|down-regulation of quinolinate synthesis|negative regulation of quinolinate synthesis|inhibition of quinolinate anabolism|downregulation of quinolinate biosynthesis|down-regulation of quinolinate formation|negative regulation of quinolinate formation|downregulation of quinolinate biosynthetic process|inhibition of quinolinate synthesis|down regulation of quinolinate biosynthesis|down regulation of quinolinate biosynthetic process|inhibition of quinolinate biosynthetic process|inhibition of quinolinate biosynthesis|inhibition of quinolinate formation Any process that stops, prevents or reduces the frequency, rate or extent of quinolinate biosynthetic process. GO:1904984 regulation of quinolinate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904984 regulation of quinolinate anabolism|regulation of quinolinate synthesis|regulation of quinolinate formation|regulation of quinolinate biosynthesis Any process that modulates the frequency, rate or extent of quinolinate biosynthetic process. GO:0047169 galactarate O-hydroxycinnamoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047169 EC:2.3.1.130|KEGG_REACTION:R03727|RHEA:12997|MetaCyc:2.3.1.130-RXN galacturate hydroxycinnamoyltransferase activity|feruloyl-CoA:galactarate O-(hydroxycinnamoyl)transferase activity Catalysis of the reaction: feruloyl-CoA + galactarate = 2-(E)-O-feruloyl-D-galactarate + CoA. GO:0047168 isocitrate O-dihydroxycinnamoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047168 KEGG_REACTION:R01946|RHEA:20756|MetaCyc:2.3.1.126-RXN|EC:2.3.1.126 caffeoyl-CoA:isocitrate 3-O-(3,4-dihydroxycinnamoyl)transferase activity Catalysis of the reaction: caffeoyl-CoA + isocitrate = 2-caffeoylisocitrate + CoA. GO:1904983 glycine import into mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904983 transmembrane glycine transport from cytosol to mitochondrion The process in which glycine is transported from the cytosol, into the mitochondrial matrix. GO:1904982 sucrose transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904982 The process in which sucrose is transported across a membrane. GO:0047167 1-alkyl-2-acetylglycerol O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047167 RHEA:21996|MetaCyc:2.3.1.125-RXN|EC:2.3.1.125 acyl-CoA:1-O-alkyl-2-acetyl-sn-glycerol O-acyltransferase activity|1-hexadecyl-2-acetylglycerol acyltransferase activity Catalysis of the reaction: 1-O-alkyl-2-acetyl-sn-glycerol + acyl-CoA = 1-O-alkyl-2-acetyl-3-acyl-sn-glycerol + CoA. GO:1904992 positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904992 activation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|up-regulation of dopamine receptor, adenylate cyclase inhibiting pathway|up regulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|positive regulation of dopamine receptor, adenylyl cyclase inhibiting pathway|positive regulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|up-regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway|activation of adenylate cyclase-inhibiting dopamine receptor signaling pathway|up regulation of dopamine receptor, adenylyl cyclase inhibiting pathway|activation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|upregulation of dopamine receptor, adenylate cyclase inhibiting pathway|positive regulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|up regulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|up-regulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|upregulation of dopamine receptor, adenylyl cyclase inhibiting pathway|up regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway|up regulation of dopamine receptor, adenylate cyclase inhibiting pathway|activation of dopamine receptor, adenylate cyclase inhibiting pathway|positive regulation of dopamine receptor, adenylate cyclase inhibiting pathway|upregulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|upregulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|up-regulation of dopamine receptor, adenylyl cyclase inhibiting pathway|activation of dopamine receptor, adenylyl cyclase inhibiting pathway|upregulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway|up-regulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway Any process that activates or increases the frequency, rate or extent of adenylate cyclase-inhibiting dopamine receptor signaling pathway. GO:1904991 negative regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904991 inhibition of dopamine receptor, adenylate cyclase inhibiting pathway|negative regulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|down-regulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|down-regulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|downregulation of dopamine receptor, adenylyl cyclase inhibiting pathway|negative regulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|down-regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway|down regulation of dopamine receptor, adenylyl cyclase inhibiting pathway|down regulation of dopamine receptor, adenylate cyclase inhibiting pathway|inhibition of dopamine receptor, adenylyl cyclase inhibiting pathway|downregulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|downregulation of dopamine receptor, adenylate cyclase inhibiting pathway|inhibition of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|downregulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway|down regulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|inhibition of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|down regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway|negative regulation of dopamine receptor, adenylate cyclase inhibiting pathway|inhibition of adenylate cyclase-inhibiting dopamine receptor signaling pathway|down-regulation of dopamine receptor, adenylate cyclase inhibiting pathway|down regulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|down-regulation of dopamine receptor, adenylyl cyclase inhibiting pathway|downregulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|negative regulation of dopamine receptor, adenylyl cyclase inhibiting pathway Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase-inhibiting dopamine receptor signaling pathway. GO:1904990 regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904990 regulation of dopamine receptor, adenylyl cyclase inhibiting pathway|regulation of dopamine receptor, adenylate cyclase inhibiting pathway|regulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|regulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway Any process that modulates the frequency, rate or extent of adenylate cyclase-inhibiting dopamine receptor signaling pathway. GO:0072109 glomerular mesangium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072109 The process whose specific outcome is the progression of the glomerular mesangium over time, from its formation to the mature structure. The glomerular mesangium is the thin membrane connective tissue composed of mesangial cells, which helps to support the capillary loops in a renal glomerulus. GO:0072108 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072108 Any process that increases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros. GO:0072107 positive regulation of ureteric bud formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072107 Any process that increases the rate or extent of the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. GO:0072106 regulation of ureteric bud formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072106 Any process that modulates the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. GO:0072105 ureteric peristalsis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072105 A wavelike sequence of involuntary muscular contraction and relaxation that passes along the ureter, impelling the contents onwards. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder. GO:0072104 glomerular capillary formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072104 The process that gives rise to a glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts. GO:0072103 glomerulus vasculature morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072103 The process in which the anatomical structures of the glomerulus vasculature are generated and organized. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus. GO:0072102 glomerulus morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072102 The process in which the anatomical structures of the glomerulus are generated and organized. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney. GO:0072101 specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072101 specification of ureteric bud anterior/posterior symmetry by BMP signalling pathway|specification of ureteric bud anterior/posterior asymmetry by BMP signaling pathway A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that results in the establishment of the ureteric bud such that there is a similar arrangement in form and relationship of parts along its anterior/posterior axis. GO:0072133 metanephric mesenchyme morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072133 The process in which the anatomical structures of a metanephric mesenchymal tissue are generated and organized. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros. GO:0047177 glycerophospholipid arachidonoyl-transferase (CoA-independent) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047177 MetaCyc:2.3.1.147-RXN|EC:2.3.1.147|RHEA:15409 1-organyl-2-arachidonoyl-sn-glycero-3-phosphocholine:1-organyl-2-lyso-sn-glycero-3-phosphoethanolamine arachidonoyltransferase (CoA-independent)|1-organyl-2-arachidonyl-sn-glycero-3-phosphocholine:1-organyl-2-lyso-sn-glycero-3-phosphoethanolamine arachidonoyltransferase (CoA-independent) Catalysis of the reaction: 1-alkyl-2-lyso-sn-glycero-3-phosphoethanolamine + 1-alkyl-2-arachidonyl-sn-glycero-3-phosphocholine = 1-alkyl-2-lyso-sn-glycero-3-phosphocholine + 1-alkyl-2-arachidonyl-sn-glycero-3-phosphoethanolamine. GO:0047176 beta-glucogallin-tetrakisgalloylglucose O-galloyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047176 RHEA:19109|KEGG_REACTION:R04498|MetaCyc:2.3.1.143-RXN|EC:2.3.1.143 beta-glucogallin:1,2,3,6-tetra-O-galloyl-beta-D-glucose 4-O-galloyltransferase activity|beta-glucogallin-tetragalloylglucose 4-galloyltransferase activity|beta-glucogallin:1,2,3,6-tetra-O-galloylglucose 4-O-galloyltransferase activity|1-O-galloyl-beta-D-glucose:1,2,3,6-tetrakis-O-galloyl-beta-D-glucose 4-O-galloyltransferase activity Catalysis of the reaction: 1,2,3,6-tetrakis-O-galloyl-beta-D-glucose + 1-O-galloyl-beta-D-glucose = 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose + D-glucose. GO:0072132 mesenchyme morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072132 The process in which the anatomical structures of a mesenchymal tissue are generated and organized. A mesenchymal tissue is made up of loosely packed stellate cells. GO:0047175 galactosylacylglycerol O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047175 RHEA:17057|MetaCyc:2.3.1.141-RXN|EC:2.3.1.141 acyl-acyl-carrier-protein:D-galactosylacylglycerol O-acyltransferase activity|acyl-ACP:lyso-MGDG acyltransferase activity|acyl-acyl-carrier protein: lysomonogalactosyldiacylglycerol acyltransferase activity Catalysis of the reaction: sn-3-D-galactosyl-sn-2-acylglycerol + acyl-[acyl-carrier protein] = D-galactosyldiacylglycerol + [acyl-carrier protein]. GO:0072131 kidney mesenchyme morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072131 The process in which the anatomical structures of a kidney mesenchymal tissue are generated and organized. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney. GO:0047174 putrescine N-hydroxycinnamoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047174 RHEA:12436|MetaCyc:2.3.1.138-RXN|EC:2.3.1.138|KEGG_REACTION:R01944 hydroxycinnamoyl-CoA:putrescine hydroxycinnamoyltransferase activity|PHT|caffeoyl-CoA putrescine N-caffeoyl transferase activity|putrescine hydroxycinnamoyltransferase activity|putrescine hydroxycinnamoyl transferase activity|caffeoyl-CoA:putrescine N-(3,4-dihydroxycinnamoyl)transferase activity Catalysis of the reaction: caffeoyl-CoA + putrescine = N-caffeoylputrescine + CoA + H(+). GO:0072130 renal capsule specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072130 The regionalization process in which the identity of the renal capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized. GO:0047173 phosphatidylcholine-retinol O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047173 Reactome:R-HSA-975608|RHEA:17469|MetaCyc:2.3.1.135-RXN|EC:2.3.1.135 lecithin--retinol acyltransferase activity|phosphatidylcholine:retinol-(cellular-retinol-binding-protein) O-acyltransferase activity|phosphatidylcholine:retinol-[cellular-retinol-binding-protein] O-acyltransferase activity Catalysis of the reaction: retinol-[cellular-retinol-binding-protein] + phosphatidylcholine = retinyl-ester-[cellular-retinol-binding-protein] + 2-acylglycerophosphocholine. GO:0047172 shikimate O-hydroxycinnamoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047172 RHEA:12124|MetaCyc:2.3.1.133-RXN|EC:2.3.1.133 shikimate hydroxycinnamoyltransferase activity|4-coumaroyl-CoA:shikimate O-(hydroxycinnamoyl)transferase activity Catalysis of the reaction: shikimate + coumaroyl-CoA = 4-coumaroylshikimate + CoA. GO:0047171 glucarolactone O-hydroxycinnamoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047171 MetaCyc:2.3.1.132-RXN|RHEA:14261|EC:2.3.1.132 sinapoyl-CoA:glucarolactone O-(hydroxycinnamoyl)transferase activity Catalysis of the reaction: glucarolactone + sinapoyl-CoA = O-sinapoylglucarolactone + CoA. GO:0047170 glucarate O-hydroxycinnamoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047170 MetaCyc:2.3.1.131-RXN|EC:2.3.1.131|RHEA:23308|KEGG_REACTION:R02899 sinapoyl-CoA:glucarate O-(hydroxycinnamoyl)transferase activity Catalysis of the reaction: D-glucarate + sinapoyl-CoA = 2-O-sinapoyl-D-glucarate + CoA. GO:1904999 positive regulation of leukocyte adhesion to arterial endothelial cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904999 upregulation of leukocyte adhesion to arterial endothelial cell|up regulation of leukocyte adhesion to arterial endothelial cell|activation of leukocyte adhesion to arterial endothelial cell|up-regulation of leukocyte adhesion to arterial endothelial cell Any process that activates or increases the frequency, rate or extent of leukocyte adhesion to arterial endothelial cell. GO:1904998 negative regulation of leukocyte adhesion to arterial endothelial cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904998 down regulation of leukocyte adhesion to arterial endothelial cell|downregulation of leukocyte adhesion to arterial endothelial cell|down-regulation of leukocyte adhesion to arterial endothelial cell|inhibition of leukocyte adhesion to arterial endothelial cell Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte adhesion to arterial endothelial cell. GO:1904997 regulation of leukocyte adhesion to arterial endothelial cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904997 Any process that modulates the frequency, rate or extent of leukocyte adhesion to arterial endothelial cell. GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904996 upregulation of leukocyte adhesion to vascular endothelial cell|up regulation of leukocyte adhesion to vascular endothelial cell|activation of leukocyte adhesion to vascular endothelial cell|up-regulation of leukocyte adhesion to vascular endothelial cell Any process that activates or increases the frequency, rate or extent of leukocyte adhesion to vascular endothelial cell. GO:1904995 negative regulation of leukocyte adhesion to vascular endothelial cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904995 down regulation of leukocyte adhesion to vascular endothelial cell|downregulation of leukocyte adhesion to vascular endothelial cell|down-regulation of leukocyte adhesion to vascular endothelial cell|inhibition of leukocyte adhesion to vascular endothelial cell Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte adhesion to vascular endothelial cell. GO:1904994 regulation of leukocyte adhesion to vascular endothelial cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904994 Any process that modulates the frequency, rate or extent of leukocyte adhesion to vascular endothelial cell. GO:0047179 platelet-activating factor acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047179 RHEA:11048|MetaCyc:2.3.1.149-RXN|EC:2.3.1.149 1-alkyl-2-acyl-sn-glycero-3-phosphocholine:1-organyl-2-lyso-sn-glycero-3-phospholipid acetyltransferase activity|PAF acetyltransferase activity Catalysis of the reaction: 1-radyl-2-acyl-sn-glycero-3-phospholipid + 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine = 1-alkyl-2-lyso-sn-glycero-3-phosphocholine + 1-radyl-2-acetyl-sn-glycero-3-phospholipid. GO:1904993 obsolete positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in positive regulation of G2/M transition of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904993 upregulation of cyclin-dependent protein kinase activity involved in positive regulation of G2/M transition of mitotic cell cycle|up regulation of cyclin-dependent protein kinase activity involved in positive regulation of mitotic entry|activation of cyclin-dependent protein kinase activity involved in positive regulation of mitotic entry|positive regulation of CDK activity involved in positive regulation of mitotic entry|up regulation of cyclin-dependent protein kinase activity involved in positive regulation of G2/M transition of mitotic cell cycle|positive regulation of CDK activity involved in positive regulation of G2/M transition of mitotic cell cycle|activation of cyclin-dependent protein kinase activity involved in positive regulation of G2/M transition of mitotic cell cycle|stimulation of cyclin-dependent protein kinase activity involved in positive regulation of mitotic entry|positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in positive regulation of mitotic entry|stimulation of cyclin-dependent protein kinase activity involved in positive regulation of G2/M transition of mitotic cell cycle|up-regulation of cyclin-dependent protein kinase activity involved in positive regulation of mitotic entry|up-regulation of cyclin-dependent protein kinase activity involved in positive regulation of G2/M transition of mitotic cell cycle|upregulation of cyclin-dependent protein kinase activity involved in positive regulation of mitotic entry OBSOLETE. Any positive regulation of cyclin-dependent protein serine/threonine kinase activity that is involved in positive regulation of G2/M transition of mitotic cell cycle. GO:0047178 glycerophospholipid acyltransferase (CoA-dependent) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047178 RHEA:20972|MetaCyc:2.3.1.148-RXN|EC:2.3.1.148 1-organyl-2-acyl-sn-glycero-3-phosphocholine:1-organyl-2-lyso-sn-glycero-3-phosphoethanolamine acyltransferase (CoA-dependent) Catalysis of the reaction: 1-radyl-2-lyso-sn-glycero-3-phosphoethanolamine + 1-radyl-2-acyl-sn-glycero-3-phosphocholine = 1-radyl-2-lyso-sn-glycero-3-phosphocholine + 1-radyl-2-acyl-sn-glycero-3-phosphoethanolamine. GO:0047180 salutaridinol 7-O-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047180 RHEA:22856|KEGG_REACTION:R04723|MetaCyc:2.3.1.150-RXN|EC:2.3.1.150 acetyl-CoA:salutaridinol 7-O-acetyltransferase activity Catalysis of the reaction: (7S)-salutaridinol + acetyl-CoA = (7S)-O-acetylsalutaridinol + CoA. GO:0072139 glomerular parietal epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072139 The process in which a relatively unspecialized cell acquires specialized features of a glomerular parietal epithelial cell. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. GO:0072138 mesenchymal cell proliferation involved in ureteric bud development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072138 ureteric bud mesenchymal cell proliferation The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureteric bud, that contributes to ureteric bud development. GO:0072137 condensed mesenchymal cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072137 The multiplication or reproduction of cells, resulting in the expansion of a condensed mesenchymal cell population. A condensed mesenchymal cell population is a population of adherent mesenchymal cells. SO:0001720 epigenetically_modified_region biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0001720 epigenetically modified region A biological region implicated in inherited changes caused by mechanisms other than changes in the underlying DNA sequence. GO:0072136 metanephric mesenchymal cell proliferation involved in metanephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072136 The multiplication or reproduction of cells, resulting in the expansion of a metanephric mesenchymal cell population. GO:0072135 kidney mesenchymal cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072135 The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population in the kidney. GO:0072134 nephrogenic mesenchyme morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072134 The process in which the anatomical structures of a nephrogenic mesenchymal tissue are generated and organized. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron. GO:0047188 aromatic-hydroxylamine O-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047188 EC:2.3.1.56|RHEA:20325|MetaCyc:2.3.1.56-RXN arylhydroxamate acyltransferase activity|N-hydroxy-2-acetylaminofluorene N-O acyltransferase activity|N-hydroxy-4-acetylaminobiphenyl:N-hydroxy-4-aminobiphenyl O-acetyltransferase activity|arylhydroxamic acid N,O-acetyltransferase activity|aromatic hydroxylamine acetyltransferase activity|arylhydroxamic acyltransferase activity|N,O-acetyltransferase activity Catalysis of the reaction: N-hydroxy-4-aminobiphenyl + N-hydroxy-4-acetylaminonbiphenyl = N-acetoxy-4-aminobiphenyl + N-hydroxy-4-aminobiphenyl. GO:0072122 extraglomerular mesangial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072122 Goormaghtigh proliferation|lacis cell proliferation The multiplication or reproduction of extraglomerular glomerular mesangium cells by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa. GO:0047187 deacetyl-[citrate-(pro-3S)-lyase] S-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047187 EC:2.3.1.49|RHEA:20393|MetaCyc:2.3.1.49-RXN deacetyl-citrate-(pro-3S)-lyase S-acetyltransferase activity|S-acetylphosphopantetheine:deacetyl-citrate-oxaloacetate-lyase((pro-3S)-CH2COO-rightacetate)S-acetyltransferase activity|S-acetyl phosphopantetheine:deacetyl citrate lyase S-acetyltransferase activity|deacetyl-citrate-(pro-3S)-lyase acetyltransferase activity Catalysis of the reaction: deacetyl-[citrate-oxaloacetate-lyase ((pro-3S)-CH(2)COO(-)-acetate)] + S-acetylphosphopantetheine = [citrate oxaloacetate-lyase ((pro-3S)-CH(2)COO(-)-acetate)] + pantetheine 4'-phosphate. GO:0072121 head kidney maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072121 A developmental process, independent of morphogenetic (shape) change, that is required for the head kidney to attain its fully functional state. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney. GO:0047186 N-acetylneuraminate 7-O(or 9-O)-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047186 RHEA:20808|EC:2.3.1.45|MetaCyc:2.3.1.45-RXN acetyl-CoA:N-acetylneuraminate-7- or 8-O-acetyltransferase activity|acetyl-CoA:N-acetylneuraminate 7-O(or 9-O)-acetyltransferase activity|N-acetylneuraminate 7(8)-O-acetyltransferase activity|glycoprotein 7(9)-O-acetyltransferase activity|N-acetylneuraminate O7-(or O9-)acetyltransferase activity|sialate O-acetyltransferase|acetyl-CoA:N-acetylneuraminate-7- and/or 8-O-acetyltransferase activity|N-acetylneuraminate 7,8-O-acetyltransferase activity|acetyl-CoA:N-acetylneuraminate-9(or 7)-O-acetyltransferase activity|acetyl-CoA:N-acetylneuraminate-9(7)-O-acetyltransferase activity Catalysis of the reaction: N-acetylneuraminate + acetyl-CoA = N-acetyl-7-O(or 9-O)-acetylneuraminate + CoA. GO:0072120 pronephros maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072120 pronephric kidney maturation A developmental process, independent of morphogenetic (shape) change, that is required for the pronephros to attain its fully functional state. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life. GO:0047185 N-acetylneuraminate 4-O-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047185 KEGG_REACTION:R01806|EC:2.3.1.44|RHEA:18305|MetaCyc:2.3.1.44-RXN sialate O-acetyltransferase|acetyl-CoA:N-acetylneuraminate 4-O-acetyltransferase activity Catalysis of the reaction: N-acetylneuraminate + acetyl-CoA = N-acetyl-4-O-acetylneuraminate + CoA. GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047184 RHEA:12937|EC:2.3.1.23|Reactome:R-HSA-1482794|MetaCyc:2.3.1.23-RXN acyl coenzyme A-monoacylphosphatidylcholine acyltransferase activity|lysophosphatidylcholine acyltransferase activity|lysolecithin acyltransferase activity|acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase activity|acyl-CoA:1-acyl-glycero-3-phosphocholine transacylase activity|1-acyl-sn-glycero-3-phosphocholine acyltransferase activity|lysophosphatide acyltransferase activity Catalysis of the reaction: 1-acyl-sn-glycero-3-phosphocholine + acyl-CoA = phosphatidylcholine + CoA. GO:0047183 anthocyanin 5-aromatic acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047183 MetaCyc:RXN-7945|RHEA:15661|EC:2.3.1.153 hydroxycinnamoyl-CoA:anthocyanidin 3,5-diglucoside 5-O-glucoside-6'''-O-hydroxycinnamoyltransferase activity Catalysis of the reaction: anthocyanidin-3,5-diglucoside + hydroxycinnamoyl-CoA = anthocyanidin 3-glucoside-5-hydroxycinnamoylglucoside + CoA. GO:0047182 alcohol O-cinnamoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047182 RHEA:23524|MetaCyc:2.3.1.152-RXN|EC:2.3.1.152 1-O-trans-cinnamoyl-beta-D-glucopyranose:alcohol O-cinnamoyltransferase activity Catalysis of the reaction: an alcohol + 1-O-trans-cinnamoyl-beta-D-glucopyranose = beta-D-glucose + alkyl cinnamate. GO:0047181 tetrahydroxybenzophenone synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047181 RHEA:19305|MetaCyc:2.3.1.151-RXN|EC:2.3.1.151 malonyl-CoA:3-hydroxybenzoyl-CoA malonyltransferase activity Catalysis of the reaction: 3-hydroxybenzoyl-CoA + 3 malonyl-CoA = 3 CO2 + 2,3',4,6-tetrahydroxybenzophenone + 4 coenzyme A. GO:0047189 2,3-diaminopropionate N-oxalyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047189 EC:2.3.1.58|RHEA:13465|KEGG_REACTION:R04211|MetaCyc:2.3.1.58-RXN oxalyldiaminopropionic synthase activity|oxalyl-CoA:L-2,3-diaminopropanoate N3-oxalyltransferase activity|ODAP synthase activity|oxalyl-CoA:L-2,3-diaminopropanoate 3-N-oxalyltransferase activity|oxalyl-CoA:L-alpha,beta-diaminopropionic acid oxalyltransferase activity|oxalyldiaminopropionate synthase activity Catalysis of the reaction: 3-amino-L-alanine + oxalyl-CoA = N(3)-oxalyl-L-2,3-diaminopropanoate + CoA. GO:0047191 1-alkylglycerophosphocholine O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047191 RHEA:23992|MetaCyc:2.3.1.63-RXN|EC:2.3.1.63 acyl-CoA:1-alkyl-sn-glycero-3-phosphocholine O-acyltransferase activity Catalysis of the reaction: 1-alkyl-sn-glycero-3-phosphocholine + acyl-CoA = 1-alkyl-2-acyl-sn-glycero-3-phosphocholine + CoA. GO:0072129 renal capsule formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072129 The developmental process pertaining to the initial formation of a renal capsule from unspecified parts. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands. GO:0047190 2-acylglycerophosphocholine O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047190 MetaCyc:2.3.1.62-RXN|KEGG_REACTION:R01319|EC:2.3.1.62|RHEA:10332 2-acylglycerol-3-phosphorylcholine acyltransferase activity|2-acylglycerophosphocholine acyltransferase activity|acyl-CoA:2-acyl-sn-glycero-3-phosphocholine O-acyltransferase activity Catalysis of the reaction: 2-acyl-sn-glycero-3-phosphocholine + acyl-CoA = 1,2-diacyl-sn-glycero-3-phosphocholine + CoA. GO:0072128 renal capsule morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072128 The process in which the anatomical structures of the renal capsule are generated and organized. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands. GO:0072127 renal capsule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072127 The process whose specific outcome is the progression of the renal capsule over time, from its formation to the mature structure. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands. GO:0072126 positive regulation of glomerular mesangial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072126 Any process that increases the frequency, rate or extent of glomerular mesangial cell proliferation. GO:0072125 negative regulation of glomerular mesangial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072125 Any process that decreases the frequency, rate or extent of glomerular mesangial cell proliferation. GO:0072124 regulation of glomerular mesangial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072124 Any process that modulates the frequency, rate or extent of glomerular mesangial cell proliferation. GO:0072123 intraglomerular mesangial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072123 The multiplication or reproduction of intraglomerular glomerular mesangium cells by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis. GO:0047199 phosphatidylcholine-dolichol O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047199 EC:2.3.1.83|RHEA:19285|MetaCyc:2.3.1.83-RXN|KEGG_REACTION:R04227 3-sn-phosphatidylcholine:dolichol O-acyltransferase activity Catalysis of the reaction: 1,2-diacyl-sn-glycero-3-phosphocholine + dolichol = 1-acyl-sn-glycero-3-phosphocholine + acyldolichol. GO:0072155 epithelial cell migration involved in nephron tubule morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072155 The orderly movement of epithelial cells within a renal tubule that contributes to nephron tubule morphogenesis. GO:0072154 proximal convoluted tubule segment 1 cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072154 S1 cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into an S1 cell in the kidney. GO:0047198 cysteine-S-conjugate N-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047198 KEGG_REACTION:R04950|EC:2.3.1.80|RHEA:19213|Reactome:R-HSA-5433066|MetaCyc:2.3.1.80-RXN acetyl-CoA:S-substituted L-cysteine N-acetyltransferase activity Catalysis of the reaction: S-substituted L-cysteine + acetyl-CoA = S-substituted N-acetyl-L-cysteine + CoA + H(+). GO:0047197 triglyceride-sterol O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047197 RHEA:16897|MetaCyc:2.3.1.77-RXN|EC:2.3.1.77 triacylglycerol:sterol acyltransferase activity|triacylglycerol:3beta-hydroxysterol O-acyltransferase activity|triacylglycerol-sterol O-acyltransferase activity Catalysis of the reaction: a 3-beta-hydroxysterol + triacylglycerol = a 3-beta-hydroxysterol ester + 1,2-diacylglycerol. GO:0072153 renal interstitial fibroblast fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072153 kidney interstitial cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a renal fibroblast. GO:0072152 glomerular mesangial cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072152 The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular mesangial cell. GO:0047196 long-chain-alcohol O-fatty-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047196 MetaCyc:RXNQT-4193|RHEA:38443|Reactome:R-HSA-8848582|MetaCyc:2.3.1.75-RXN|Reactome:R-HSA-5696424|EC:2.3.1.75 acyl-CoA:long-chain-alcohol O-acyltransferase activity|wax-ester synthase activity|wax synthase activity|wax ester synthase activity Catalysis of the reaction: a long-chain-alcohol + acyl-CoA = a long-chain ester + CoA. GO:0072151 mesangial cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072151 The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesangial cell. GO:0047195 diacylglycerol-sterol O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047195 RHEA:13301|MetaCyc:2.3.1.73-RXN|EC:2.3.1.73 1,2-diacyl-sn-glycerol:sterol acyl transferase activity|1,2-diacyl-sn-glycerol:sterol O-acyltransferase activity Catalysis of the reaction: sterol + 1,2-diacylglycerol = sterol ester + acylglycerol. GO:0047194 indoleacetylglucose-inositol O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047194 KEGG_REACTION:R04333|RHEA:21180|MetaCyc:2.3.1.72-RXN|EC:2.3.1.72 indole-3-acetyl-beta-1-D-glucoside:myo-inositol indoleacetyltransferase activity|1-O-(indol-3-ylacetyl)-beta-D-glucose:myo-inositol indole-3-ylacetyltransferase activity|1-O-(indol-3-yl)acetyl-beta-D-glucose:myo-inositol (indol-3-yl)acetyltransferase activity Catalysis of the reaction: 1-O-(indol-3-ylacetyl)-beta-D-glucose + myo-inositol = 1L-1-O-(indol-3-yl)acetyl-myo-inositol + D-glucose. GO:0072150 juxtaglomerulus cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072150 The process in which the developmental fate of a cell becomes restricted such that it will develop into a juxtaglomerulus cell. GO:0047193 obsolete CDP-acylglycerol O-arachidonoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047193 MetaCyc:2.3.1.70-RXN arachidonyl-CoA:CDP-acylglycerol O-arachidonyltransferase activity|CDP-acylglycerol O-arachidonyltransferase activity|arachidonoyl-CoA:CDP-acylglycerol O-arachidonoyltransferase activity|CDPacylglycerol O-arachidonyltransferase activity|CDP-acylglycerol O-arachidonoyltransferase activity OBSOLETE. Catalysis of the reaction: CDP-acylglycerol + arachidonyl-CoA = CDP-diacylglycerol + CoA. GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047192 MetaCyc:2.3.1.67-RXN|RHEA:18461|EC:2.3.1.67 acetyl-CoA:lyso-PAF acetyltransferase activity|blood platelet-activating factor acetyltransferase activity|lyso-GPC:acetyl CoA acetyltransferase activity|lyso-platelet activating factor:acetyl-CoA acetyltransferase activity|platelet-activating factor-synthesizing enzyme activity|acyl-CoA:1-alkyl-sn-glycero-3-phosphocholine acyltransferase activity|lysoPAF:acetyl CoA acetyltransferase activity|acetyl-CoA:1-alkyl-2-lyso-sn-glycero-3-phosphocholine 2-O-acetyltransferase activity|acetyl-CoA:1-alkyl-sn-glycero-3-phosphocholine 2-O-acetyltransferase activity|lysopaf:acetyl CoA acetyltransferase activity|lyso-platelet-activating factor:acetyl-CoA acetyltransferase activity|1-alkyl-2-lysolecithin acetyltransferase activity|1-alkyl-2-lyso-sn-glycero-3-phosphocholine acetyltransferase activity|platelet-activating factor acylhydrolase activity Catalysis of the reaction: 1-alkyl-sn-glycero-3-phosphocholine + acetyl-CoA = 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + CoA. GO:0072159 epithelial cell migration involved in proximal tubule morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072159 The orderly movement of epithelial cells within a renal tubule that contributes to proximal tubule morphogenesis. GO:0072158 proximal tubule morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072158 The process in which the anatomical structures of a proximal tubule are generated and organized. The proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology. GO:0072157 epithelial cell migration involved in distal tubule morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072157 The orderly movement of epithelial cells within a renal tubule that contributes to distal tubule morphogenesis. GO:0072156 distal tubule morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072156 The process in which the anatomical structures of a distal tubule are generated and organized. The distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule. GO:0072144 glomerular mesangial cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072144 The process whose specific outcome is the progression of a glomerular mesangial cell in the kidney over time, from its formation to the mature structure. GO:0072143 mesangial cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072143 The process whose specific outcome is the progression of a mesangial cell in the kidney over time, from its formation to the mature structure. GO:0072142 juxtaglomerulus cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072142 The process whose specific outcome is the progression of a juxtaglomerulus cell over time, from its formation to the mature structure. GO:0072141 renal interstitial fibroblast development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072141 kidney interstitial cell development The process whose specific outcome is the progression of a renal interstitial fibroblast over time, from its formation to the mature structure. GO:0072140 DCT cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072140 distal convoluted tubule cell development The process whose specific outcome is the progression of a distal convoluted tubule cell over time, from its formation to the mature structure. GO:0072149 glomerular visceral epithelial cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072149 podocyte cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular visceral epithelial cell. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells. GO:0072148 epithelial cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072148 The process in which the developmental fate of a cell becomes restricted such that it will develop into an epithelial cell. GO:0072147 glomerular parietal epithelial cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072147 Bowman's capsule cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular parietal epithelial cell. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes. GO:0072146 DCT cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072146 distal convoluted tubule cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a distal convoluted tubule cell. GO:0072145 proximal convoluted tubule segment 1 cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072145 S1 cell development The process whose specific outcome is the progression of an S1 cell in the kidney over time, from its formation to the mature structure. CL:0002265 type D cell of colon biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002265 colonic delta cell|colon D-cell|delta cell of colon A D cell located in the colon. CL:0002264 type A cell of stomach biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002264 A type of enteroendocrine cell found in the stomach that secretes glucagon. CL:0002267 type D cell of stomach biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002267 stomach D-cell|stomach delta cell|delta cell of stomach A type D cell found in the stomach. CL:0002266 type D cell of small intestine biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002266 delta cell of small intestine|small intestine D-cell|small intestine delta cell A type D cell of the small intestine. CHEBI:74463 lysophosphatidylinositol 16:0(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74463 CL:0002260 epithelial cell of parathyroid gland biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002260 An epithelial cell of the parathyroid gland. CHEBI:74466 lysophosphatidylinositol 18:1(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74466 CHEBI:74465 lysophosphatidylinositol 18:0(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74465 CHEBI:25501 neoxanthin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25501 CHEBI:74478 2'-O-methyluridine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74478 CHEBI:25500 neopterins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25500 CHEBI:25505 neuraminate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25505 CL:0002275 pancreatic PP cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002275 pancreatic polypeptide-secreting cell|PP-cell of pancreatic islet|PP cell of pancreatic islet A PP cell located in the islets of the pancreas. CHEBI:25508 neuraminic acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25508 CHEBI:25506 neuraminates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25506 CHEBI:74474 (R)-3-hydroxyhexanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74474 CHEBI:74477 2'-O-methyladenosine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74477 CL:0002274 histamine secreting cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002274 A cell type that secretes histamine. CHEBI:74476 (11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74476 CHEBI:74489 (13Z,16Z,19Z,22Z)-octacosatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74489 CL:0002242 nucleate cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002242 A cell containing at least one nucleus. CHEBI:74480 N(7)-methylguanosine 5'-phosphate zwitterion residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74480 CHEBI:74481 N(2)-methylguanosine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74481 CHEBI:74483 5-methylcytidine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74483 CHEBI:74486 N(3)-methylpseudouridine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74486 CHEBI:74485 (13Z,16Z,19Z,22Z)-3-oxooctacosatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74485 CL:0002240 marrow fibroblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002240 A fibroblast in the bone marrow. GO:1904909 positive regulation of maintenance of mitotic sister chromatid cohesion, telomeric biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904909 up regulation of maintenance of sister chromatin cohesion at telomere at mitosis|activation of maintenance of sister chromatin cohesion at telomere at mitosis|positive regulation of maintenance of mitotic sister chromatin cohesion at telomere|positive regulation of maintenance of sister chromatin cohesion at telomere at mitosis|up regulation of maintenance of mitotic sister chromatid cohesion, telomeric|up-regulation of maintenance of telomeric mitotic sister chromatin cohesion|activation of maintenance of telomeric mitotic sister chromatin cohesion|activation of maintenance of mitotic sister chromatid cohesion, telomeric|up regulation of maintenance of mitotic sister chromatin cohesion at telomere|up-regulation of maintenance of sister chromatin cohesion at telomere at mitosis|upregulation of maintenance of mitotic sister chromatin cohesion at telomere|positive regulation of maintenance of telomeric mitotic sister chromatin cohesion|up-regulation of maintenance of mitotic sister chromatid cohesion, telomeric|up regulation of maintenance of telomeric mitotic sister chromatin cohesion|upregulation of maintenance of sister chromatin cohesion at telomere at mitosis|activation of maintenance of mitotic sister chromatin cohesion at telomere|up-regulation of maintenance of mitotic sister chromatin cohesion at telomere|upregulation of maintenance of mitotic sister chromatid cohesion, telomeric|upregulation of maintenance of telomeric mitotic sister chromatin cohesion Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric. GO:1904908 negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904908 downregulation of maintenance of sister chromatin cohesion at telomere at mitosis|down-regulation of maintenance of mitotic sister chromatin cohesion at telomere|negative regulation of maintenance of mitotic sister chromatin cohesion at telomere|downregulation of maintenance of mitotic sister chromatid cohesion, telomeric|down-regulation of maintenance of sister chromatin cohesion at telomere at mitosis|negative regulation of maintenance of sister chromatin cohesion at telomere at mitosis|downregulation of maintenance of mitotic sister chromatin cohesion at telomere|down-regulation of maintenance of mitotic sister chromatid cohesion, telomeric|negative regulation of maintenance of telomeric mitotic sister chromatin cohesion|down-regulation of maintenance of telomeric mitotic sister chromatin cohesion|down regulation of maintenance of mitotic sister chromatin cohesion at telomere|inhibition of maintenance of sister chromatin cohesion at telomere at mitosis|inhibition of maintenance of mitotic sister chromatin cohesion at telomere|inhibition of maintenance of mitotic sister chromatid cohesion, telomeric|downregulation of maintenance of telomeric mitotic sister chromatin cohesion|down regulation of maintenance of telomeric mitotic sister chromatin cohesion|down regulation of maintenance of sister chromatin cohesion at telomere at mitosis|inhibition of maintenance of telomeric mitotic sister chromatin cohesion|down regulation of maintenance of mitotic sister chromatid cohesion, telomeric Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric. GO:1904907 regulation of maintenance of mitotic sister chromatid cohesion, telomeric biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904907 regulation of maintenance of mitotic sister chromatin cohesion at telomere|regulation of maintenance of telomeric mitotic sister chromatin cohesion|regulation of maintenance of sister chromatin cohesion at telomere at mitosis Any process that modulates the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric. GO:1904906 positive regulation of endothelial cell-matrix adhesion via fibronectin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904906 up regulation of endothelial cell-matrix adhesion via fibronectin|upregulation of endothelial cell-matrix adhesion via fibronectin|up-regulation of endothelial cell-matrix adhesion via fibronectin|activation of endothelial cell-matrix adhesion via fibronectin Any process that activates or increases the frequency, rate or extent of endothelial cell-matrix adhesion via fibronectin. GO:1904905 negative regulation of endothelial cell-matrix adhesion via fibronectin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904905 down-regulation of endothelial cell-matrix adhesion via fibronectin|downregulation of endothelial cell-matrix adhesion via fibronectin|down regulation of endothelial cell-matrix adhesion via fibronectin|inhibition of endothelial cell-matrix adhesion via fibronectin Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell-matrix adhesion via fibronectin. GO:1904904 regulation of endothelial cell-matrix adhesion via fibronectin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904904 Any process that modulates the frequency, rate or extent of endothelial cell-matrix adhesion via fibronectin. GO:1904903 ESCRT III complex disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904903 The disaggregation of an ESCRT III complex into its constituent components. GO:1904902 ESCRT III complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904902 ESCRT III complex formation The aggregation, arrangement and bonding together of a set of components to form an ESCRT III complex. GO:1904901 positive regulation of myosin II filament organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904901 upregulation of myosin II filament organization|activation of myosin II polymerization or depolymerization|up regulation of myosin II filament organisation|activation of myosin II filament assembly or disassembly|activation of myosin II filament organisation|positive regulation of myosin II filament organisation|positive regulation of myosin II polymerization or depolymerization|up regulation of myosin II polymerization or depolymerization|positive regulation of myosin II filament assembly or disassembly|up regulation of myosin II filament organization|up regulation of myosin II filament assembly or disassembly|activation of myosin II filament organization|up-regulation of myosin II filament organisation|upregulation of myosin II polymerization or depolymerization|upregulation of myosin II filament assembly or disassembly|up-regulation of myosin II filament organization|upregulation of myosin II filament organisation|up-regulation of myosin II polymerization or depolymerization|up-regulation of myosin II filament assembly or disassembly Any process that activates or increases the frequency, rate or extent of myosin II filament organization. GO:1904900 negative regulation of myosin II filament organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904900 downregulation of myosin II filament organisation|down-regulation of myosin II polymerization or depolymerization|negative regulation of myosin II polymerization or depolymerization|down regulation of myosin II filament organization|down-regulation of myosin II filament assembly or disassembly|negative regulation of myosin II filament assembly or disassembly|downregulation of myosin II filament organization|negative regulation of myosin II filament organisation|down-regulation of myosin II filament organisation|downregulation of myosin II polymerization or depolymerization|downregulation of myosin II filament assembly or disassembly|down regulation of myosin II polymerization or depolymerization|inhibition of myosin II filament organisation|down-regulation of myosin II filament organization|down regulation of myosin II filament assembly or disassembly|inhibition of myosin II polymerization or depolymerization|inhibition of myosin II filament organization|inhibition of myosin II filament assembly or disassembly|down regulation of myosin II filament organisation Any process that stops, prevents or reduces the frequency, rate or extent of myosin II filament organization. CL:0002254 epithelial cell of small intestine biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002254 An epithelial cell of the small intestine. CL:0002253 epithelial cell of large intestine biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002253 epithelial cell of colon An epithelial cell of the large intestine. CL:0002257 epithelial cell of thyroid gland biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002257 An epithelial cell of thyroid gland. CHEBI:74491 N(1)-methyladenosine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74491 CHEBI:74493 N(6),N(6)-dimethyladenosine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74493 PR:000012421 proliferating cell nuclear antigen biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000012421 PCNA|cyclin A protein that is a translation product of the human PCNA gene or a 1:1 ortholog thereof. CHEBI:74495 2'-O-methylcytidine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74495 CHEBI:74497 2-methyladenosine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74497 CHEBI:74496 (15Z,18Z,21Z,24Z)-3-oxotriacontatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74496 CL:0002252 epithelial cell of esophagus biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002252 An epithelial cell of the esophagus. CHEBI:74499 (15Z,18Z,21Z,24Z)-triacontatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74499 CL:0002251 epithelial cell of alimentary canal biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002251 An epithelial cell of the musculomembranous digestive tube extending from the mouth to the anus. GO:1904919 transmembrane L-cystine transport from lysosomal lumen to cytosol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904919 The directed movement of L-cystine from the lysosomal lumen across the lysosomal membrane and into the cytosol. GO:1904918 transmembrane L-histidine transport from lysosomal lumen to cytosol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904918 The directed movement of L-histidine from the lysosomal lumen across the lysosomal membrane and into the cytosol. GO:1904917 L-arginine transmembrane transport from lysosomal lumen to cytosol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904917 transmembrane L-arginine transport from lysosomal lumen to cytosol The directed movement of L-arginine across a membrane from lysosomal lumen to cytosol. GO:1904916 transmembrane L-lysine transport from lysosomal lumen to cytosol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904916 The directed movement of L-lysine from the lysosomal lumen across the lysosomal membrane and into the cytosol. GO:1904915 positive regulation of establishment of protein-containing complex localization to telomere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904915 positive regulation of establishment of macromolecular complex localisation to telomere|up regulation of establishment of macromolecular complex localisation to telomere|up regulation of establishment of macromolecular complex localization to telomere|upregulation of establishment of macromolecular complex localisation to telomere|upregulation of establishment of macromolecular complex localization to telomere|up-regulation of establishment of macromolecular complex localisation to telomere|activation of establishment of macromolecular complex localisation to telomere|up-regulation of establishment of macromolecular complex localization to telomere|activation of establishment of macromolecular complex localization to telomere|positive regulation of establishment of macromolecular complex localization to telomere Any process that activates or increases the frequency, rate or extent of establishment of the localization of a protein-containing macromolecular complex to a telomere. GO:1904914 negative regulation of establishment of protein-containing complex localization to telomere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904914 down-regulation of establishment of macromolecular complex localization to telomere|downregulation of establishment of macromolecular complex localisation to telomere|down regulation of establishment of macromolecular complex localisation to telomere|inhibition of establishment of macromolecular complex localisation to telomere|downregulation of establishment of macromolecular complex localization to telomere|down regulation of establishment of macromolecular complex localization to telomere|inhibition of establishment of macromolecular complex localization to telomere|negative regulation of establishment of macromolecular complex localization to telomere|negative regulation of establishment of macromolecular complex localisation to telomere|down-regulation of establishment of macromolecular complex localisation to telomere Any process that stops, prevents or reduces the frequency, rate or extent of establishment of the localization of a protein-containing macromolecular complex to a telomere. GO:1904913 regulation of establishment of protein-containing complex localization to telomere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904913 regulation of establishment of macromolecular complex localization to telomere|regulation of establishment of macromolecular complex localisation to telomere Any process that modulates the frequency, rate or extent of establishment of the localization of a protein-containing macromolecular complex to a telomere. GO:1904912 positive regulation of establishment of RNA localization to telomere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904912 upregulation of establishment of RNA localization to telomere|up regulation of establishment of RNA localisation to telomere|activation of establishment of RNA localisation to telomere|positive regulation of establishment of RNA localisation to telomere|up regulation of establishment of RNA localization to telomere|activation of establishment of RNA localization to telomere|up-regulation of establishment of RNA localisation to telomere|up-regulation of establishment of RNA localization to telomere|upregulation of establishment of RNA localisation to telomere Any process that activates or increases the frequency, rate or extent of establishment of RNA localization to telomere. GO:1904911 negative regulation of establishment of RNA localization to telomere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904911 down regulation of establishment of RNA localization to telomere|downregulation of establishment of RNA localization to telomere|down-regulation of establishment of RNA localisation to telomere|negative regulation of establishment of RNA localisation to telomere|down-regulation of establishment of RNA localization to telomere|inhibition of establishment of RNA localisation to telomere|inhibition of establishment of RNA localization to telomere|down regulation of establishment of RNA localisation to telomere|downregulation of establishment of RNA localisation to telomere Any process that stops, prevents or reduces the frequency, rate or extent of establishment of RNA localization to telomere. GO:1904910 regulation of establishment of RNA localization to telomere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904910 regulation of establishment of RNA localisation to telomere Any process that modulates the frequency, rate or extent of establishment of RNA localization to telomere. CL:1000497 kidney cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000497 CL:0002222 vertebrate lens cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002222 A cell comprising the transparent, biconvex body separating the posterior chamber and vitreous body, and constituting part of the refracting mechanism of the mammalian eye. CL:1000495 small intestine goblet cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000495 small intestinal goblet cell|goblet cell of epithelium of small intestine|goblet cell of small intestine A goblet cell that is part of the small intestine. CL:1000494 nephron tubule epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000494 kidney tubule epithelial cell An epithelial cell that is part of a nephron tubule. CL:1000490 mesothelial cell of peritoneum biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000490 peritoneal mesothelial cell A mesothelial cell that is part of the peritoneum. GO:0047100 glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047100 RHEA:10296|MetaCyc:1.2.1.13-RXN|EC:1.2.1.13 triosephosphate dehydrogenase (NADP+) activity|triosephosphate dehydrogenase (NADP(+)) activity|dehydrogenase, glyceraldehyde phosphate (nicotinamide adenine dinucleotide phosphate) (phosphorylating)|triosephosphate dehydrogenase (NADP)|NADP-dependent glyceraldehyde-3-phosphate dehydrogenase activity|NADP-triose phosphate dehydrogenase activity|NADP-dependent glyceraldehyde phosphate dehydrogenase activity|glyceraldehyde phosphate dehydrogenase (nicotinamide adenine dinucleotide phosphate) (phosphorylating)|D-glyceraldehyde-3-phosphate:NADP+ oxidoreductase (phosphorylating) Catalysis of the reaction: phosphate + NADP+ + glyceraldehyde-3-phosphate = NADPH + 3-phospho-D-glyceroyl-phosphate. GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1904929 coreceptor activity involved in Wnt-JNK signaling pathway|coreceptor, insoluble ligand activity involved in Wnt-activated signaling pathway, planar cell polarity pathway|coreceptor, insoluble ligand activity involved in planar cell polarity pathway|Wnt co-receptor activity, non-canonical signaling|coreceptor, insoluble ligand activity involved in PCP pathway|coreceptor, insoluble ligand activity involved in Wnt signaling pathway, planar cell polarity pathway|coreceptor activity involved in non-canonical Wnt signaling pathway|coreceptor activity involved in Wnt receptor signalling pathway, planar cell polarity pathway|coreceptor, soluble ligand activity involved in planar cell polarity pathway|coreceptor activity involved in Wnt-PCP signaling pathway|coreceptor, soluble ligand activity involved in Wnt-JNK signaling pathway|coreceptor activity involved in Wnt-activated signaling pathway, planar cell polarity pathway|coreceptor, insoluble ligand activity involved in Wnt receptor signaling pathway, planar cell polarity pathway|coreceptor activity involved in planar cell polarity pathway|coreceptor activity involved in PCP pathway|coreceptor, insoluble ligand activity involved in Wnt-JNK signaling pathway|coreceptor, soluble ligand activity involved in Wnt receptor signaling pathway, planar cell polarity pathway|coreceptor, soluble ligand activity involved in non-canonical Wnt signaling pathway|coreceptor, soluble ligand activity involved in Wnt-PCP signaling pathway|coreceptor, insoluble ligand activity involved in non-canonical Wnt signaling pathway|coreceptor activity involved in Wnt receptor signaling pathway, planar cell polarity pathway|coreceptor, soluble ligand activity involved in Wnt receptor signalling pathway, planar cell polarity pathway|Wnt co-receptor, non-canonical pathway|coreceptor, insoluble ligand activity involved in Wnt-PCP signaling pathway|Wnt/PCP co-receptor activity|coreceptor, soluble ligand activity involved in Wnt-activated signaling pathway, planar cell polarity pathway|coreceptor, insoluble ligand activity involved in Wnt receptor signalling pathway, planar cell polarity pathway|coreceptor, soluble ligand activity involved in PCP pathway|coreceptor, soluble ligand activity involved in Wnt signaling pathway, planar cell polarity pathway Any coreceptor activity that is involved in Wnt signaling pathway, planar cell polarity pathway. GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1904928 coreceptor, soluble ligand activity involved in Wnt receptor signalling pathway through beta-catenin|coreceptor activity involved in Wnt receptor signaling pathway via beta-catenin|coreceptor activity involved in frizzled-1 receptor signaling pathway|coreceptor, insoluble ligand activity involved in canonical Wnt receptor signaling pathway|coreceptor, soluble ligand activity involved in Wnt receptor signaling pathway through beta-catenin|coreceptor activity involved in Wnt receptor signalling pathway through beta-catenin|coreceptor, soluble ligand activity involved in canonical Wnt receptor signaling pathway|coreceptor, insoluble ligand activity involved in Wnt receptor signaling pathway through beta-catenin|coreceptor, soluble ligand activity involved in canonical Wnt-activated signaling pathway|Wnt co-receptor, canonical pathway|coreceptor, soluble ligand activity involved in Wnt receptor signaling pathway via beta-catenin|coreceptor, soluble ligand activity involved in canonical Wnt signaling pathway|coreceptor, insoluble ligand activity involved in canonical Wnt-activated signaling pathway|coreceptor activity involved in canonical Wnt receptor signaling pathway|coreceptor, insoluble ligand activity involved in Wnt receptor signaling pathway via beta-catenin|coreceptor, insoluble ligand activity involved in canonical Wnt signaling pathway|coreceptor, soluble ligand activity involved in frizzled-1 receptor signaling pathway|coreceptor activity involved in Wnt receptor signaling pathway through beta-catenin|Wnt co-receptor activity, canonical signaling|coreceptor, insoluble ligand activity involved in Wnt receptor signalling pathway through beta-catenin|coreceptor, insoluble ligand activity involved in frizzled-1 receptor signaling pathway|coreceptor activity involved in canonical Wnt-activated signaling pathway Any coreceptor activity that is involved in a canonical Wnt signaling pathway. GO:1904927 cellular response to palmitoleic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904927 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a palmitoleic acid stimulus. GO:1904926 response to palmitoleic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904926 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a palmitoleic acid stimulus. GO:1904925 positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904925 upregulation of mitophagy in response to mitochondrial depolarization|up regulation of mitophagy in response to mitochondrial depolarization|activation of mitophagy in response to mitochondrial depolarization|up-regulation of mitophagy in response to mitochondrial depolarization Any process that activates or increases the frequency, rate or extent of autophagy of the mitochondrion in response to mitochondrial depolarization. GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904924 down regulation of mitophagy in response to mitochondrial depolarization|downregulation of mitophagy in response to mitochondrial depolarization|down-regulation of mitophagy in response to mitochondrial depolarization|inhibition of mitophagy in response to mitochondrial depolarization Any process that stops, prevents or reduces the frequency, rate or extent of mitophagy in response to mitochondrial depolarization. GO:0047108 (R)-3-hydroxyacid-ester dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047108 KEGG_REACTION:R04105|RHEA:24352|MetaCyc:1.2.1.55-RXN|EC:1.1.1.279 3-oxo ester (R)-reductase activity|(R)-3-hydroxyacid ester dehydrogenase activity|ethyl-(R)-3-hydroxyhexanoate:NADP+ 3-oxidoreductase activity Catalysis of the reaction: ethyl (R)-3-hydroxyhexanoate + NADP(+) = ethyl 3-oxohexanoate + H(+) + NADPH. GO:1904923 regulation of autophagy of mitochondrion in response to mitochondrial depolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904923 Any process that modulates the frequency, rate or extent of autophagy of mitochondrion in response to mitochondrial depolarization. GO:1904922 positive regulation of MAPK cascade involved in axon regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904922 upregulation of mitogen-activated protein kinase cascade involved in axon regeneration|up-regulation of MAPK signalling involved in axon regeneration|activation of MAPKKK cascade during sporulation involved in axon regeneration|activation of MAPK signaling involved in axon regeneration|activation of MAP kinase cascade involved in axon regeneration|activation of MAP kinase kinase kinase cascade involved in axon regeneration|up-regulation of MAP kinase cascade involved in axon regeneration|up-regulation of MAP kinase kinase kinase cascade involved in axon regeneration|positive regulation of MAPK signal transduction involved in axon regeneration|up-regulation of ERK/MAPK cascade involved in axon regeneration|positive regulation of MAPK signaling involved in axon regeneration|up-regulation of MAPKKK cascade during sporulation involved in axon regeneration|up regulation of MAPK signal transduction involved in axon regeneration|positive regulation of MAPKKK cascade involved in axon regeneration|up regulation of MAPK signaling involved in axon regeneration|activation of mitogen-activated protein kinase cascade involved in axon regeneration|up-regulation of mitogen-activated protein kinase cascade involved in axon regeneration|upregulation of MAPK signalling involved in axon regeneration|up regulation of MAPK cascade involved in axon regeneration|up regulation of MAPKKK cascade involved in axon regeneration|activation of ERK/MAPK cascade involved in axon regeneration|positive regulation of MAP kinase cascade involved in axon regeneration|positive regulation of MAP kinase kinase kinase cascade involved in axon regeneration|upregulation of MAPKKK cascade during sporulation involved in axon regeneration|positive regulation of ERK/MAPK cascade involved in axon regeneration|up regulation of MAP kinase kinase kinase cascade involved in axon regeneration|upregulation of MAPK signal transduction involved in axon regeneration|up regulation of MAP kinase cascade involved in axon regeneration|up regulation of ERK/MAPK cascade involved in axon regeneration|up regulation of MAPK signalling involved in axon regeneration|upregulation of MAPK signaling involved in axon regeneration|upregulation of MAPKKK cascade involved in axon regeneration|positive regulation of mitogen-activated protein kinase cascade involved in axon regeneration|upregulation of MAPK cascade involved in axon regeneration|positive regulation of MAPK signalling involved in axon regeneration|up regulation of mitogen-activated protein kinase cascade involved in axon regeneration|activation of MAPK signalling involved in axon regeneration|up-regulation of MAPK signal transduction involved in axon regeneration|up regulation of MAPKKK cascade during sporulation involved in axon regeneration|activation of MAPK signal transduction involved in axon regeneration|upregulation of MAP kinase cascade involved in axon regeneration|upregulation of MAP kinase kinase kinase cascade involved in axon regeneration|up-regulation of MAPK signaling involved in axon regeneration|positive regulation of MAPKKK cascade during sporulation involved in axon regeneration|up-regulation of MAPKKK cascade involved in axon regeneration|upregulation of ERK/MAPK cascade involved in axon regeneration|up-regulation of MAPK cascade involved in axon regeneration|activation of MAPK cascade involved in axon regeneration|activation of MAPKKK cascade involved in axon regeneration Any process that activates or increases the frequency, rate or extent of MAPK cascade involved in axon regeneration. GO:0047107 gamma-guanidinobutyraldehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047107 KEGG_REACTION:R03177|MetaCyc:1.2.1.54-RXN|RHEA:14381|EC:1.2.1.54 alpha-guanidinobutyraldehyde dehydrogenase activity|4-guanidinobutyraldehyde dehydrogenase activity|GBAL dehydrogenase activity|4-guanidinobutanal:NAD+ 1-oxidoreductase activity Catalysis of the reaction: 4-guanidinobutanal + H(2)O + NAD(+) = 4-guanidinobutanoate + 2 H(+) + NADH. GO:0047106 4-hydroxyphenylacetaldehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047106 MetaCyc:1.2.1.53-RXN|RHEA:17273|EC:1.2.1.53 4-HPAL dehydrogenase activity|4-hydroxyphenylacetaldehyde:NAD+ oxidoreductase activity Catalysis of the reaction: NAD+ + (4-hydroxyphenyl)acetaldehyde + H2O = NADH + 4-hydroxyphenylacetate. GO:1904921 negative regulation of MAPK cascade involved in axon regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904921 down-regulation of MAPKKK cascade during sporulation involved in axon regeneration|down-regulation of MAPK signal transduction involved in axon regeneration|negative regulation of MAPKKK cascade during sporulation involved in axon regeneration|negative regulation of MAPK signal transduction involved in axon regeneration|inhibition of ERK/MAPK cascade involved in axon regeneration|negative regulation of MAPK signaling involved in axon regeneration|down-regulation of MAPK signaling involved in axon regeneration|down-regulation of MAPK cascade involved in axon regeneration|negative regulation of MAPKKK cascade involved in axon regeneration|down-regulation of MAPKKK cascade involved in axon regeneration|inhibition of MAPK signalling involved in axon regeneration|downregulation of MAPK signal transduction involved in axon regeneration|negative regulation of MAP kinase cascade involved in axon regeneration|negative regulation of MAP kinase kinase kinase cascade involved in axon regeneration|downregulation of MAPK signaling involved in axon regeneration|down-regulation of MAP kinase kinase kinase cascade involved in axon regeneration|down regulation of MAPK signalling involved in axon regeneration|down-regulation of MAP kinase cascade involved in axon regeneration|downregulation of MAPKKK cascade involved in axon regeneration|downregulation of MAPK cascade involved in axon regeneration|inhibition of MAPKKK cascade during sporulation involved in axon regeneration|negative regulation of ERK/MAPK cascade involved in axon regeneration|down-regulation of ERK/MAPK cascade involved in axon regeneration|down regulation of MAPK signal transduction involved in axon regeneration|downregulation of MAPK signalling involved in axon regeneration|down regulation of MAPK signaling involved in axon regeneration|negative regulation of mitogen-activated protein kinase cascade involved in axon regeneration|down-regulation of mitogen-activated protein kinase cascade involved in axon regeneration|down regulation of MAPK cascade involved in axon regeneration|inhibition of MAPK signal transduction involved in axon regeneration|down regulation of MAPKKK cascade involved in axon regeneration|inhibition of MAPK cascade involved in axon regeneration|inhibition of MAPKKK cascade involved in axon regeneration|downregulation of MAP kinase kinase kinase cascade involved in axon regeneration|downregulation of MAP kinase cascade involved in axon regeneration|down regulation of MAPKKK cascade during sporulation involved in axon regeneration|inhibition of MAPK signaling involved in axon regeneration|downregulation of ERK/MAPK cascade involved in axon regeneration|downregulation of MAPKKK cascade during sporulation involved in axon regeneration|negative regulation of MAPK signalling involved in axon regeneration|down regulation of MAP kinase kinase kinase cascade involved in axon regeneration|down-regulation of MAPK signalling involved in axon regeneration|down regulation of MAP kinase cascade involved in axon regeneration|downregulation of mitogen-activated protein kinase cascade involved in axon regeneration|inhibition of MAP kinase cascade involved in axon regeneration|down regulation of ERK/MAPK cascade involved in axon regeneration|inhibition of MAP kinase kinase kinase cascade involved in axon regeneration|down regulation of mitogen-activated protein kinase cascade involved in axon regeneration|inhibition of mitogen-activated protein kinase cascade involved in axon regeneration Any process that stops, prevents or reduces the frequency, rate or extent of MAPK cascade involved in axon regeneration. GO:1904920 regulation of MAPK cascade involved in axon regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904920 regulation of MAPK signal transduction involved in axon regeneration|regulation of MAPK signalling involved in axon regeneration|regulation of MAPK signaling involved in axon regeneration|regulation of MAPKKK cascade involved in axon regeneration|regulation of MAPKKK cascade during sporulation involved in axon regeneration|regulation of MAP kinase kinase kinase cascade involved in axon regeneration|regulation of MAP kinase cascade involved in axon regeneration|regulation of ERK/MAPK cascade involved in axon regeneration|regulation of mitogen-activated protein kinase cascade involved in axon regeneration Any process that modulates the frequency, rate or extent of MAPK cascade involved in axon regeneration. GO:0047105 4-trimethylammoniobutyraldehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047105 RHEA:17985|MetaCyc:1.2.1.47-RXN|EC:1.2.1.47 4-trimethylaminobutyraldehyde dehydrogenase activity|4-N-trimethylaminobutyraldehyde dehydrogenase activity|4-trimethylammoniobutanal:NAD+ 1-oxidoreductase activity Catalysis of the reaction: NAD+ + 4-trimethylammoniobutanal = NADH + 4-trimethylammoniobutanoate. GO:0047104 hexadecanal dehydrogenase (acylating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047104 KEGG_REACTION:R01277|UM-BBD_reactionID:r1374|MetaCyc:1.2.1.42-RXN|EC:1.2.1.42|RHEA:19705 fatty acyl-CoA reductase activity|hexadecanal:NAD+ oxidoreductase (CoA-acylating) Catalysis of the reaction: CoA + NAD(+) + palmitaldehyde = H(+) + NADH + palmitoyl-CoA. GO:0047103 3-alpha,7-alpha,12-alpha-trihydroxycholestan-26-al 26-oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047103 RHEA:24584|MetaCyc:1.2.1.40-RXN trihydroxydeoxycoprostanal dehydrogenase activity|3-alpha,7-alpha,12-alpha-trihydroxycholestan-26-al 26-dehydrogenase activity|3alpha,7alpha,12alpha-trihydroxycholestan-26-al 26-dehydrogenase activity|3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al dehydrogenase activity|cholestanetriol-26-al 26-dehydrogenase activity|THAL-NAD oxidoreductase activity|3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al:NAD+ 26-oxidoreductase activity|3alpha,7alpha,12alpha-trihydroxycholestan-26-al 26-oxidoreductase activity Catalysis of the reaction: H2O + NAD+ + 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestan-26-al = NADH + 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate. GO:0047102 aminomuconate-semialdehyde dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047102 MetaCyc:1.2.1.32-RXN|Reactome:R-HSA-71239|EC:1.2.1.32|UM-BBD_reactionID:r1434|RHEA:14469 2-hydroxymuconic acid semialdehyde dehydrogenase activity|2-hydroxymuconic semialdehyde dehydrogenase activity|2-aminomuconate semialdehyde dehydrogenase activity|2-aminomuconate-6-semialdehyde:NAD+ 6-oxidoreductase activity|alpha-hydroxymuconic epsilon-semialdehyde dehydrogenase activity|2-hydroxymuconate semialdehyde dehydrogenase activity|alpha-aminomuconic epsilon-semialdehyde dehydrogenase activity Catalysis of the reaction: H2O + NAD+ + 2-aminomuconate semialdehyde = NADH + 2-amino-muconate. GO:0047101 2-oxoisovalerate dehydrogenase (acylating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047101 MetaCyc:1.2.1.25-RXN|EC:1.2.1.25|RHEA:13997 3-methyl-2-oxobutanoate:NAD+ 2-oxidoreductase (CoA-methyl-propanoylating)|2-oxoisovalerate dehydrogenase activity Catalysis of the reaction: NAD+ + CoA + 2-keto-isovalerate = NADH + CO2 + isobutyryl-CoA. CL:1000488 cholangiocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000488 epithelial cell of bile duct An epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water. They are cuboidal epithelium in the small interlobular bile ducts, but become columnar and mucus secreting in larger bile ducts approaching the porta hepatis and the extrahepatic ducts. CL:0002231 epithelial cell of prostate biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002231 prostate epithelial cell An epithelial cell of the prostate. CL:1000487 smooth muscle cell of prostate biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000487 smooth muscle fiber of prostate A smooth muscle cell that is part of the prostate gland. CL:0002234 basal cell of prostatic acinus biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002234 basal epithelial cell of prostatic acinus A cell of the basal layer of the epithelium in the prostatic acinus. CL:1000486 basal cell of urothelium biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000486 A basal cell that is part of the urothelium. CL:0002233 epithelial cell of prostatic acinus biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002233 acinar epithelial cell of prostate An epithelial cell of the prostatic acinus. CL:1000484 Purkinje myocyte of atrioventricular bundle biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000484 A Purkinje myocyte that is part of the atrioventricular bundle. GO:0047109 (S)-3-hydroxyacid-ester dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047109 KEGG_REACTION:R04106|RHEA:18269|MetaCyc:1.2.1.56-RXN|EC:1.1.1.280 ethyl-(S)-3-hydroxyhexanoate:NADP+ 3-oxidoreductase activity|(S)-3-hydroxyacid ester dehydrogenase activity|3-oxo ester (S)-reductase activity Catalysis of the reaction: ethyl (S)-3-hydroxyhexanoate + NADP(+) = ethyl 3-oxohexanoate + H(+) + NADPH. SO:0001797 centromeric_repeat biolink:SequenceFeature go-plus http://purl.obolibrary.org/obo/SO_0001797 INSDC_feature:repeat_region|INSDC_qualifier:centromeric_repeat|centromeric repeat A repeat region found within the modular centromere. SO:0001796 regional_centromere_central_core biolink:SequenceFeature go-plus http://purl.obolibrary.org/obo/SO_0001796 regional centromere central core A conserved region within the central region of a modular centromere, where the kinetochore is formed. SO:0001799 regional_centromere_outer_repeat_region biolink:SequenceFeature go-plus http://purl.obolibrary.org/obo/SO_0001799 regional centromere outer repeat region The heterochromatic outer repeat region of a modular centromere. These repeats exist in tandem arrays on both chromosome arms. SO:0001798 regional_centromere_inner_repeat_region biolink:SequenceFeature go-plus http://purl.obolibrary.org/obo/SO_0001798 regional centromere inner repeat region|lmr1R|lmr1L|lmr repeat The inner inverted repeat region of a modular centromere and part of the central core surrounding a non-conserved central region. This region is adjacent to the central core, on each chromosome arm. GO:0047111 formate dehydrogenase (cytochrome-c-553) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047111 EC:1.17.2.3|MetaCyc:1.2.2.3-RXN|RHEA:15189 formate dehydrogenase (cytochrome c-553)|formate:ferricytochrome-c-553 oxidoreductase activity Catalysis of the reaction: ferricytochrome C-553 + formate = ferrocytochrome C-553 + CO2. GO:0047110 phenylglyoxylate dehydrogenase (acylating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047110 EC:1.2.1.58|KEGG_REACTION:R02450|RHEA:10372|MetaCyc:1.2.1.58-RXN phenylglyoxylate:NAD+ oxidoreductase activity Catalysis of the reaction: CoA + NAD(+) + phenylglyoxylate = benzoyl-CoA + CO(2) + NADH. GO:1904939 regulation of DNA nucleotidylexotransferase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904939 regulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|regulation of deoxyribonucleic nucleotidyltransferase activity|regulation of deoxyribonucleic acid nucleotidyltransferase activity|regulation of terminal deoxynucleotide transferase activity|regulation of terminal transferase activity|regulation of deoxynucleotidyl terminal transferase activity|regulation of terminal addition enzyme activity|regulation of terminal deoxynucleotidyltransferase activity|regulation of terminal deoxyribonucleotidyltransferase activity|regulation of TdT|regulation of addase activity Any process that modulates the frequency, rate or extent of DNA nucleotidylexotransferase activity. GO:1904938 planar cell polarity pathway involved in axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904938 Wnt receptor signaling pathway, planar cell polarity pathway involved in axon guidance|planar cell polarity pathway involved in axon chemotaxis|PCP pathway involved in axon guidance|Wnt-PCP signaling pathway involved in axon chemotaxis|Wnt-PCP signaling pathway involved in axon pathfinding|Wnt receptor signalling pathway, planar cell polarity pathway involved in axon chemotaxis|Wnt signaling pathway, planar cell polarity pathway involved in axon guidance|Wnt-PCP signaling involved in axon guidance|non-canonical Wnt signaling pathway involved in axon pathfinding|Wnt-activated signaling pathway, planar cell polarity pathway involved in axon chemotaxis|Wnt receptor signaling pathway, planar cell polarity pathway involved in axon chemotaxis|PCP pathway involved in axon chemotaxis|Wnt signaling pathway, planar cell polarity pathway involved in axon chemotaxis|Wnt-JNK signaling pathway involved in axon pathfinding|planar cell polarity pathway involved in axon growth cone guidance|Wnt-JNK signaling pathway involved in axon growth cone guidance|Wnt receptor signalling pathway, planar cell polarity pathway involved in axon growth cone guidance|Wnt-JNK signaling pathway involved in axon guidance|Wnt-activated signaling pathway, planar cell polarity pathway involved in axon growth cone guidance|Wnt signaling pathway, planar cell polarity pathway involved in axon pathfinding|PCP pathway involved in axon pathfinding|non-canonical Wnt signaling pathway involved in axon growth cone guidance|Wnt receptor signaling pathway, planar cell polarity pathway involved in axon growth cone guidance|Wnt receptor signaling pathway, planar cell polarity pathway involved in axon pathfinding|planar cell polarity pathway involved in axon guidance|Wnt-activated signaling pathway, planar cell polarity pathway involved in axon pathfinding|PCP pathway involved in axon growth cone guidance|Wnt-JNK signaling pathway involved in axon chemotaxis|Wnt signaling pathway, planar cell polarity pathway involved in axon growth cone guidance|Wnt-PCP signaling pathway involved in axon growth cone guidance|non-canonical Wnt signaling pathway involved in axon guidance|Wnt receptor signalling pathway, planar cell polarity pathway involved in axon guidance|Wnt receptor signalling pathway, planar cell polarity pathway involved in axon pathfinding|Wnt-PCP signaling pathway involved in axon guidance|non-canonical Wnt signaling pathway involved in axon chemotaxis|Wnt-activated signaling pathway, planar cell polarity pathway involved in axon guidance|planar cell polarity pathway involved in axon pathfinding Any Wnt signaling pathway, planar cell polarity pathway that is involved in axon guidance. GO:1904937 sensory neuron migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904937 The orderly movement of a sensory neuron from one site to another. GO:1904936 interneuron migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904936 inter neuron migration|inter-neuron migration The orderly movement of an interneuron from one site to another. GO:1904935 positive regulation of cell proliferation in midbrain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904935 up regulation of cell proliferation in mesencephalon|positive regulation of cell proliferation in mesencephalon|upregulation of mesencepahalic cell proliferation|upregulation of cell proliferation in midbrain|activation of cell proliferation in mesencephalon|up-regulation of cell proliferation in midbrain|activation of cell proliferation in midbrain|up regulation of mesencepahalic cell proliferation|up-regulation of cell proliferation in mesencephalon|positive regulation of mesencepahalic cell proliferation|activation of mesencepahalic cell proliferation|upregulation of cell proliferation in mesencephalon|up regulation of cell proliferation in midbrain|up-regulation of mesencepahalic cell proliferation Any process that activates or increases the frequency, rate or extent of cell proliferation in midbrain. GO:1904934 negative regulation of cell proliferation in midbrain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904934 inhibition of cell proliferation in midbrain|down regulation of mesencepahalic cell proliferation|negative regulation of cell proliferation in mesencephalon|down-regulation of cell proliferation in mesencephalon|downregulation of mesencepahalic cell proliferation|inhibition of cell proliferation in mesencephalon|down-regulation of mesencepahalic cell proliferation|down-regulation of cell proliferation in midbrain|negative regulation of mesencepahalic cell proliferation|down regulation of cell proliferation in mesencephalon|downregulation of cell proliferation in midbrain|downregulation of cell proliferation in mesencephalon|inhibition of mesencepahalic cell proliferation|down regulation of cell proliferation in midbrain Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in midbrain. GO:0047119 2-methyl-branched-chain-enoyl-CoA reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047119 EC:1.3.1.52|KEGG_REACTION:R03169|RHEA:24532|MetaCyc:1.3.1.52-RXN 2-methyl-branched-chain-acyl-CoA:NAD+ 2-oxidoreductase activity Catalysis of the reaction: 2-methylbutanoyl-CoA + NAD(+) = 2-methylbut-2-enoyl-CoA + H(+) + NADH. GO:1904933 regulation of cell proliferation in midbrain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904933 regulation of mesencepahalic cell proliferation|regulation of cell proliferation in mesencephalon Any process that modulates the frequency, rate or extent of cell proliferation in midbrain. GO:0047118 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047118 EC:1.3.1.40|RHEA:24268|KEGG_REACTION:R03463|MetaCyc:1.3.1.40-RXN 2,6-dioxo-6-phenylhexanoate:NADP+ delta2-oxidoreductase activity|2-hydroxy-6-oxo-phenylhexa-2,4-dienoate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity Catalysis of the reaction: 2,6-dioxo-6-phenylhexanoate + NADP(+) = 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H(+) + NADPH. GO:1904932 negative regulation of cartilage condensation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904932 downregulation of cartilage condensation|down regulation of cartilage condensation|inhibition of cartilage condensation|down-regulation of cartilage condensation Any process that stops, prevents or reduces the frequency, rate or extent of cartilage condensation. CL:0002209 intermediate epitheliocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002209 undifferentiated columnar cell of tracheobronchial tree An epithelial cell present in the trachea and bronchi; columnar in shape; generally lack cilia; immature forms of ciliated or secretory cells which have been formed from stem cells. GO:0047117 enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047117 EC:1.3.1.39|MetaCyc:1.3.1.39-RXN enoyl-acyl-carrier-protein reductase (NADPH, A-specific)|enoyl-ACp reductase activity|enoyl-[acyl-carrier protein] reductase (NADPH, A-specific) activity|acyl-acyl-carrier-protein:NADP+ oxidoreductase (A-specific)|enoyl-acyl carrier protein (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|enoyl-ACP reductase (NADPH, A-specific) activity Catalysis of the reaction: acyl-[acyl-carrier protein] + NADP+ = trans-D2-enoyl-[acyl-carrier protein] + NADPH + H+. GO:1904931 MCM complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1904931 mini-chromosome maintenance complex binding Interacting selectively and non-covalently with an MCM complex. GO:0047116 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047116 EC:1.3.1.25|RHEA:11560|MetaCyc:1.3.1.25-RXN (1R,6R)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate:NAD+ oxidoreductase (decarboxylating)|DHB dehydrogenase activity|3,5-cyclohexadiene-1,2-diol-1-carboxylic acid dehydrogenase activity|cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate:NAD+ oxidoreductase activity|cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate:NAD(+) oxidoreductase activity|2-hydro-1,2-dihydroxybenzoate dehydrogenase activity|DHBDH activity|3,5-cyclohexadiene-1,2-diol-1-carboxylate dehydrogenase activity|dihydrodihydroxybenzoate dehydrogenase activity Catalysis of the reaction: NAD+ + 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate = NADH + CO2 + catechol. GO:1904930 amphisome membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1904930 Any membrane that is part of an amphisome. GO:0047115 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047115 RHEA:16729|EC:1.3.1.20|MetaCyc:1.3.1.20-RXN trans-1,2-dihydrobenzene-1,2-diol:NADP+ oxidoreductase activity|dihydrodiol dehydrogenase activity Catalysis of the reaction: NADP+ + trans-1,2-dihydrobenzene-1,2-diol = NADPH + catechol. GO:0047114 kynurenate-7,8-dihydrodiol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047114 EC:1.3.1.18|RHEA:22248|MetaCyc:1.3.1.18-RXN|KEGG_REACTION:R03251 7,8-dihydro-7,8-dihydroxykynurenate dehydrogenase activity|7,8-dihydroxykynurenic acid 7,8-diol dehydrogenase activity|7,8-dihydro-7,8-dihydroxykynurenate:NAD+ oxidoreductase activity Catalysis of the reaction: 7,8-dihydro-7,8-dihydroxykynurenate + NAD(+) = 7,8-dihydroxykynurenate + H(+) + NADH. GO:0047113 aldehyde dehydrogenase (quinone) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047113 MetaCyc:1.2.99.3-RXN|RHEA:13881|EC:1.2.5.2 aldehyde:(pyrroloquinoline-quinone) oxidoreductase activity|aldehyde dehydrogenase (pyrroloquinoline-quinone)|aldehyde dehydrogenase (acceptor) activity Catalysis of the reaction: an aldehyde + a quinone + H2O = a carboxylate + a quinol. GO:0047112 pyruvate oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047112 RHEA:20848|KEGG_REACTION:R00207|MetaCyc:1.2.3.3-RXN|EC:1.2.3.3 phosphate-dependent pyruvate oxidase activity|pyruvate:oxygen 2-oxidoreductase (phosphorylating)|pyruvic oxidase activity Catalysis of the reaction: H(+) + O(2) + phosphate + pyruvate = acetyl phosphate + CO(2) + H(2)O(2). CL:0002202 epithelial cell of tracheobronchial tree biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002202 An epithelial cell of the tracheobronchial tree. GO:0047122 quinaldate 4-oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047122 RHEA:16697|MetaCyc:1.3.99.18-RXN|EC:1.3.99.18|KEGG_REACTION:R03687 quinaldic acid 4-oxidoreductase activity|quinoline-2-carboxylate:acceptor 4-oxidoreductase (hydroxylating) Catalysis of the reaction: A + H(2)O + quinaldate = AH(2) + kynurenate. GO:0047121 isoquinoline 1-oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047121 MetaCyc:1.3.99.16-RXN|KEGG_REACTION:R05151|EC:1.3.99.16|RHEA:11588 isoquinoline:acceptor 1-oxidoreductase (hydroxylating) Catalysis of the reaction: A + H(2)O + isoquinoline = AH(2) + isoquinolin-1(2H)-one. GO:0047120 (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047120 MetaCyc:1.3.1.53-RXN|RHEA:10744|KEGG_REACTION:R01633|EC:1.3.1.53|UM-BBD_reactionID:r0151 dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylate dehydrogenase activity|(1R,2S)-dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylate dehydrogenase activity|cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,4-dicarboxylate:NAD+ oxidoreductase (decarboxylating)|(3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate:NAD+ oxidoreductase activity|terephthalate 1,2-cis-dihydrodiol dehydrogenase activity Catalysis of the reaction: (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD(+) = 3,4-dihydroxybenzoate + CO(2) + NADH. GO:1904949 ATPase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1904949 VPS4 complex A protein complex which is capable of ATPase activity. GO:1904948 midbrain dopaminergic neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904948 midbrain DA neurogenesis|midbrain dopaminergic neuron production|DA neurogenesis from midbrain floor plate|mDA neuron differentiation The process in which a relatively unspecialized cell acquires the specialized features of a midbrain dopaminergic neuron. GO:1904947 folate import into mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904947 folic acid import into mitochondrion The process in which folic acid is transported from the cytosol, into the mitochondrial matrix. GO:1904946 obsolete cellular response to cobalt(II) acetate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904946 OBSOLETE. Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt(II) acetate stimulus. CL:0002218 immature dendritic epithelial T cell precursor biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002218 immature DEC precursor|immature DETC precursor A double negative thymocyte that has a T cell receptor consisting of a gamma chain that has as part a Vgamma3 segment, and a delta chain. This cell type is CD4-negative, CD8-negative and CD24-positive. This cell-type is found in the fetal thymus with highest numbers occurring at E17-E18. GO:1904945 obsolete response to cobalt(II) acetate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904945 OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt(II) acetate stimulus. GO:0047129 opine dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047129 RHEA:21592|MetaCyc:1.5.1.28-RXN|EC:1.5.1.28|KEGG_REACTION:R03732 (2S)-2-{[1-(R)-carboxyethyl]amino}pentanoate dehydrogenase (NAD, L-aminopentanoate-forming)|(2S)-2-{[1-(R)-carboxyethyl]amino}pentanoate:NAD+ oxidoreductase (L-aminopentanoate-forming) Catalysis of the reaction: (2S)-2-[(R)-1-carboxyethylamino]pentanoate + H(2)O + NAD(+) = L-2-aminopentanoate + H(+) + NADH + pyruvate. GO:1904944 positive regulation of cardiac ventricle formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904944 upregulation of cardiac ventricle formation|up regulation of cardiac ventricle formation|activation of cardiac ventricle formation|up-regulation of cardiac ventricle formation Any process that activates or increases the frequency, rate or extent of cardiac ventricle formation. GO:0047128 1,2-dehydroreticulinium reductase (NADPH) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047128 KEGG_REACTION:R04695|MetaCyc:1.5.1.27-RXN|EC:1.5.1.27|RHEA:17569 (R)-reticuline:NADP+ oxidoreductase activity|1,2-dehydroreticulinium ion reductase activity Catalysis of the reaction: (R)-reticuline + NADP(+) = 1,2-dehydroreticuline + H(+) + NADPH. GO:1904943 negative regulation of cardiac ventricle formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904943 down regulation of cardiac ventricle formation|downregulation of cardiac ventricle formation|down-regulation of cardiac ventricle formation|inhibition of cardiac ventricle formation Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle formation. GO:0047127 thiomorpholine-carboxylate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047127 MetaCyc:1.5.1.25-RXN|EC:1.5.1.25|Reactome:R-HSA-5693347 ketimine reductase activity|thiomorpholine-3-carboxylate:NAD(P)+ 5,6-oxidoreductase activity|ketimine-reducing enzyme Catalysis of the reaction: NAD(P)+ + thiomorpholine-3-carboxylate = NAD(P)H + 3,4-dehydro-1,4-thiomorpholine-3-carboxylate. GO:1904942 regulation of cardiac ventricle formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904942 Any process that modulates the frequency, rate or extent of cardiac ventricle formation. GO:1904941 positive regulation of DNA nucleotidylexotransferase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904941 up regulation of terminal deoxynucleotide transferase activity|up regulation of terminal transferase activity|up regulation of terminal addition enzyme activity|activation of terminal deoxynucleotide transferase activity|activation of terminal transferase activity|upregulation of terminal deoxyribonucleotidyltransferase activity|positive regulation of terminal deoxynucleotide transferase activity|upregulation of TdT|upregulation of DNA nucleotidylexotransferase activity|upregulation of deoxynucleotidyl terminal transferase activity|positive regulation of terminal transferase activity|up-regulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|positive regulation of terminal addition enzyme activity|activation of deoxyribonucleic nucleotidyltransferase activity|up-regulation of deoxyribonucleic nucleotidyltransferase activity|upregulation of addase activity|up regulation of terminal deoxynucleotidyltransferase activity|activation of terminal addition enzyme activity|activation of terminal deoxynucleotidyltransferase activity|up-regulation of deoxyribonucleic acid nucleotidyltransferase activity|positive regulation of terminal deoxynucleotidyltransferase activity|activation of deoxynucleotidyl terminal transferase activity|activation of DNA nucleotidylexotransferase activity|up-regulation of DNA nucleotidylexotransferase activity|up-regulation of deoxynucleotidyl terminal transferase activity|upregulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|up regulation of terminal deoxyribonucleotidyltransferase activity|up regulation of TdT|up-regulation of terminal deoxynucleotide transferase activity|activation of terminal deoxyribonucleotidyltransferase activity|up-regulation of terminal transferase activity|positive regulation of terminal deoxyribonucleotidyltransferase activity|positive regulation of TdT|up-regulation of terminal addition enzyme activity|positive regulation of deoxyribonucleic nucleotidyltransferase activity|up regulation of addase activity|activation of addase activity|positive regulation of addase activity|up regulation of deoxyribonucleic nucleotidyltransferase activity|upregulation of deoxyribonucleic acid nucleotidyltransferase activity|activation of TdT|up-regulation of terminal deoxynucleotidyltransferase activity|up regulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|upregulation of terminal deoxynucleotide transferase activity|positive regulation of deoxynucleotidyl terminal transferase activity|upregulation of terminal transferase activity|activation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|upregulation of terminal addition enzyme activity|up regulation of deoxynucleotidyl terminal transferase activity|up regulation of DNA nucleotidylexotransferase activity|positive regulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|up-regulation of terminal deoxyribonucleotidyltransferase activity|up-regulation of TdT|upregulation of deoxyribonucleic nucleotidyltransferase activity|up regulation of deoxyribonucleic acid nucleotidyltransferase activity|up-regulation of addase activity|activation of deoxyribonucleic acid nucleotidyltransferase activity|positive regulation of deoxyribonucleic acid nucleotidyltransferase activity|upregulation of terminal deoxynucleotidyltransferase activity Any process that activates or increases the frequency, rate or extent of DNA nucleotidylexotransferase activity. GO:0047126 N5-(carboxyethyl)ornithine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047126 RHEA:18661|MetaCyc:1.5.1.24-RXN|EC:1.5.1.24|KEGG_REACTION:R00666 5-N-(L-1-carboxyethyl)-L-ornithine:NADP+ oxidoreductase (L-ornithine-forming)|N5-(L-1-carboxyethyl)-L-ornithine:NADP+ oxidoreductase (L-ornithine-forming) Catalysis of the reaction: N(5)-[1(S)-1-carboxyethyl]-L-ornithine + H(2)O + NADP(+) = L-ornithine + H(+) + NADPH + pyruvate. GO:1904940 negative regulation of DNA nucleotidylexotransferase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904940 down regulation of terminal deoxynucleotidyltransferase activity|inhibition of DNA nucleotidylexotransferase activity|inhibition of deoxynucleotidyl terminal transferase activity|negative regulation of deoxyribonucleic acid nucleotidyltransferase activity|down-regulation of deoxyribonucleic acid nucleotidyltransferase activity|inhibition of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|downregulation of terminal deoxynucleotidyltransferase activity|down regulation of terminal deoxyribonucleotidyltransferase activity|down regulation of TdT|down-regulation of terminal deoxynucleotide transferase activity|negative regulation of terminal deoxynucleotide transferase activity|down-regulation of terminal transferase activity|negative regulation of terminal transferase activity|down-regulation of terminal addition enzyme activity|down regulation of addase activity|negative regulation of terminal addition enzyme activity|inhibition of deoxyribonucleic acid nucleotidyltransferase activity|downregulation of terminal deoxyribonucleotidyltransferase activity|downregulation of TdT|negative regulation of deoxyribonucleic nucleotidyltransferase activity|down-regulation of deoxyribonucleic nucleotidyltransferase activity|downregulation of addase activity|inhibition of terminal deoxynucleotide transferase activity|negative regulation of terminal deoxynucleotidyltransferase activity|inhibition of terminal transferase activity|down-regulation of terminal deoxynucleotidyltransferase activity|down regulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|down-regulation of DNA nucleotidylexotransferase activity|negative regulation of deoxynucleotidyl terminal transferase activity|down-regulation of deoxynucleotidyl terminal transferase activity|down-regulation of terminal deoxyribonucleotidyltransferase activity|negative regulation of terminal deoxyribonucleotidyltransferase activity|downregulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|down-regulation of TdT|negative regulation of TdT|inhibition of terminal addition enzyme activity|downregulation of deoxyribonucleic nucleotidyltransferase activity|down regulation of deoxyribonucleic acid nucleotidyltransferase activity|negative regulation of addase activity|down-regulation of addase activity|inhibition of terminal deoxynucleotidyltransferase activity|down regulation of deoxyribonucleic nucleotidyltransferase activity|inhibition of terminal deoxyribonucleotidyltransferase activity|down regulation of terminal deoxynucleotide transferase activity|downregulation of deoxyribonucleic acid nucleotidyltransferase activity|down regulation of terminal transferase activity|inhibition of deoxyribonucleic nucleotidyltransferase activity|downregulation of deoxynucleotidyl terminal transferase activity|downregulation of DNA nucleotidylexotransferase activity|down regulation of terminal addition enzyme activity|inhibition of addase activity|negative regulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|down-regulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|downregulation of terminal deoxynucleotide transferase activity|downregulation of terminal transferase activity|inhibition of TdT|down regulation of deoxynucleotidyl terminal transferase activity|down regulation of DNA nucleotidylexotransferase activity|downregulation of terminal addition enzyme activity Any process that stops, prevents or reduces the frequency, rate or extent of DNA nucleotidylexotransferase activity. GO:0047125 delta1-piperideine-2-carboxylate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047125 MetaCyc:RXN-8166|RHEA:12524|EC:1.5.1.21 1,2-didehydropipecolate reductase activity|delta 1-piperideine-2-carboxylate reductase activity|1,2-didehydropipecolic reductase activity|D1-piperideine-2-carboxylate reductase activity|L-pipecolate:NADP+ 2-oxidoreductase activity|P2C reductase activity Catalysis of the reaction: NADP+ + L-pipecolate = NADPH + delta1-piperideine-2-carboxylate. GO:0047124 L-erythro-3,5-diaminohexanoate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047124 RHEA:19633|MetaCyc:1.4.1.11-RXN|EC:1.4.1.11|KEGG_REACTION:R03349 L-erythro-3,5-diaminohexanoate:NAD+ oxidoreductase (deaminating)|L-3,5-diaminohexanoate dehydrogenase activity Catalysis of the reaction: (3S,5S)-3,5-diaminohexanoate + H(2)O + NAD(+) = (S)-5-amino-3-oxo-hexanoate + H(+) + NADH + NH(4)(+). GO:0047123 quinoline-4-carboxylate 2-oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047123 MetaCyc:1.3.99.19-RXN|EC:1.3.99.19|KEGG_REACTION:R05183|RHEA:14949 quinoline-4-carboxylic acid 2-oxidoreductase activity|quinoline-4-carboxylate:acceptor 2-oxidoreductase (hydroxylating) Catalysis of the reaction: A + H(2)O + quinoline-4-carboxylate = 2-oxo-1,2-dihydroquinoline-4-carboxylate + AH(2). CHEBI:50413 hydroxyaldehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50413 CHEBI:50411 one-colour indicator biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50411 CHEBI:50410 colour indicator biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50410 CHEBI:50418 4-hydroxyphenylglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50418 CHEBI:25450 myo-inositol trisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25450 CHEBI:50402 androstanoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50402 CHEBI:50401 cholestanoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50401 CHEBI:50406 probe biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50406 CHEBI:50404 lipoprotein cholesterol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50404 CHEBI:50403 ergostanoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50403 CHEBI:50408 visual indicator biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50408 UBERON:0002870 dorsal motor nucleus of vagus nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002870 dorsal vagal nucleus|dorsal motor nucleus of vagus|nucleus dorsalis nervi vagi|dorsal nucleus of vagus nerve|dorsal vagal nucleus|nucleus alaris (Oertel)|dorsal motor nucleus of the vagus nerve|nucleus posterior nervi vagi|vagus nucleus|posterior nucleus of vagus nerve|dorsal motor vagal nucleus|dorsal motor nucleus of the vagus|dorsal nucleus of the vagus nerve|dorsal efferent nucleus of vagus|dorsal motor nucleus of the vagus (vagal nucleus)|dorsal motor nucleus|nucleus vagalis dorsalis|dorsal motor nucleus of vagus nerve|nucleus dorsalis motorius nervi vagi|dorsal motor nucleus of vagus X nerve|nucleus alaris A cranial nerve nucleus for the vagus nerve in the medulla that lies under the floor of the fourth ventricle. It mostly serves parasympathetic vagal functions in the gastrointestinal tract, lungs, and other thoracic and abdominal vagal innervations. The cell bodies for the preganglionic parasympathetic vagal neurons that innervate the heart reside in the nucleus ambiguus.[WP,unvetted]. UBERON:0002872 inferior salivatory nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002872 inferior salivary nucleus|nucleus salivatorius caudalis|nucleus salivatorius inferior|nucleus salivarius inferior|inferior salivatary nucleus|nucleus salivatorius inferior nervi glossopharyngei In the brain, the inferior salivatory nucleus is a cluster of neurons controlling the parasympathetic input to the parotid gland. It is one of the components of the glossopharyngeal nerve. [WP,unvetted]. UBERON:0002871 hypoglossal nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002871 nucleus of hypoglossal nerve|hypoglossal XII nucleus|nucleus nervi hypoglossi|nucleus nervi hypoglossi|twelfth cranial nerve nucleus|hypoglossal nerve nucleus|nucleus hypoglossalis|hypoglossal nucleus Nucleus forming a longitudinal cell column in the medulla, close beneath the floor of the 4th ventricle, containing motor neurons that innervate the muscles of the tongue (Brodal, Neurological Anatomy, 3rd ed., 1981, pg 453) CHEBI:25435 mutagen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25435 CHEBI:74402 (17Z,20Z,23Z,26Z,29Z)-3-oxodotriacontapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74402 CHEBI:74401 (19Z,22Z,25Z,28Z,31Z)-3-oxotetratriacontapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74401 CHEBI:25432 muramic acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25432 CHEBI:74406 3-vinylbacteriochlorophyllide a(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74406 CHEBI:74405 (R)-3-hydroxydecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74405 CHEBI:25438 mycolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25438 CHEBI:25437 mycolates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25437 CHEBI:74408 3-dimethylallyl-4-hydroxyphenylpyruvate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74408 CHEBI:74409 (17Z,20Z,23Z,26Z,29Z)-dotriacontapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74409 CHEBI:25430 monoatomic polycation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25430 CHEBI:74400 (15Z,18Z,21Z,24Z,27Z)-triacontapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74400 CHEBI:74413 (13Z,16Z,19Z,22Z,25Z)-octacosapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74413 CHEBI:25446 myo-inositol monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25446 CHEBI:25445 myo-inositol hexakisphosphates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25445 CHEBI:74415 N(6)-dimethylallyladenine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74415 CHEBI:25444 myo-inositol cyclic phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25444 CHEBI:74414 3-ureidoisobutyrate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74414 CHEBI:25443 myo-inositol bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25443 CHEBI:74417 2-methylthio-N(6)-dimethylallyladenine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74417 CHEBI:74416 2-thio-N(6)-dimethylallyladenine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74416 CHEBI:25449 myo-inositol tetrakisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25449 CHEBI:74419 2-thio-N(6)-L-threonylcarbamoyladenine 5'-monophosphate(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74419 CHEBI:25448 myo-inositol phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25448 CHEBI:25447 myo-inositol pentakisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25447 CHEBI:74418 N(6)-L-threonylcarbamoyladenine 5'-monophosphate(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74418 CHEBI:25442 mycotoxin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25442 CHEBI:25441 mycothiols biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25441 CHEBI:74411 adenosine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74411 GO:0106199 obsolete translocase activity acting on amino acids and peptides linked to oxidoreductase reactions biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106199 EC:7.4.1.- OBSOLETE. Catalysis of the translocation of amino acids and peptides linked to oxidoreductase reactions. CHEBI:74424 (10Z,13Z,16Z,19Z)-docosatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74424 CHEBI:25413 monounsaturated fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25413 GO:0106198 obsolete translocase activity acting on inorganic anions linked to a decarboxylation reaction biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106198 EC:7.3.4.- OBSOLETE. Catalysis of the translocation of an inorganic anion linked to a decarboxylation reaction. CHEBI:25412 monoterpenyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25412 GO:0106197 obsolete translocase activity acting on inorganic anions linked to the hydrolysis of a diphosphate biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106197 EC:7.3.3.- OBSOLETE. Catalysis of the translocation of inorganic anions llinked to the hydrolysis of a diphosphate. CHEBI:25411 monoterpenols biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25411 CHEBI:74426 (10Z,13Z,16Z)-3-oxodocosatrienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74426 GO:0106196 obsolete translocase activity acting on inorganic anions linked to the hydrolysis of a nucleoside triphosphate biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106196 EC:7.3.2.- OBSOLETE. Catalysis of the translocation of inorganic anions linked to the hydrolysis of a nucleoside triphosphate. UBERON:0012240 urethral meatus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012240 urethral meatus|orificium urethrae externum|external meatus of urethra|external urethral orifice|orificium urethræ externum|urinary meatus|meatus urinarius|external urethral ostium|external urinary meatus external opening or orifice of the urethra through which urine and seminal fluid (in males only) leave the body; in males the meatus presents as a vertical slit normally positioned at the tip of glans penis; in females the meatus is located between the clitoris and the vagina in the vulvular vestibule of the female genitalia[MP]. CHEBI:74428 (19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74428 CHEBI:74427 (12Z,15Z,18Z,21Z)-3-oxotetracosatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74427 CHEBI:25414 monoatomic monocation biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_25414 CHEBI:74429 7-methylguanosine 5'-triphosphate(2-) group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74429 UBERON:0012242 internal urethral orifice biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012242 internal urethral ostium|internal urethral ostium|internal urinary meatus|ostium urethrae internum|vesicourethral orifice|orificium urethrae internum|internal meatus of urethra|ostium orificium internum|internal urethral orifice of urinary bladder the usually crescent-shaped opening of the urinary bladder into the urethra, placed at the anteroinferior angle (apex) of the urinary bladder trigone UBERON:0012241 male urethral meatus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012241 urethral meatus of penile urethra|distal urethral opening of male|male urethra ostium|external orifice of male urethra|ostium urethrae externum (urethra masculina)|external urethral orifice (male)|urethral opening of penile urethra A urethral meatus that is part of a male urethra[Automatically generated definition]. UBERON:0012248 cervical mucosa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012248 Lining of the head of the uterus (cervix); contains large branched glands; does not undergo sloughing. UBERON:0012247 cervical gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012247 glandulae cervicales mucus-secreting glands in the mucosa of the uterine cervix UBERON:0012239 urinary bladder vasculature biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012239 blood vessel of bladder|set of urinary bladder blood vessels|bladder vasculature|blood vessels of bladder network of tubes that carries blood through the distensible musculomembranous organ that serves to collect and store urine excreted by the kidneys[MP] CHEBI:25418 morphinane alkaloid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25418 CHEBI:74420 2-methylthio-N(6)-L-threonylcarbamoyladenine 5'-monophosphate(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74420 CHEBI:74422 4'-demethylepipodophyllotoxin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74422 CHEBI:74434 N(2),N(2),N(7)-trimethylguanosine 5'-phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74434 CHEBI:25422 muconate semialdehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25422 CHEBI:74436 (21Z,24Z,27Z,30Z,33Z)-hexatriacontapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74436 CHEBI:25427 mugineic acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25427 CHEBI:25426 mugineic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25426 CHEBI:74431 (21Z,24Z,27Z,30Z,33Z)-3-oxohexatriacontapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74431 CHEBI:74432 N(2),N(2),N(7)-trimethylguanosine 5'-triphosphate(2-) group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74432 CHEBI:74446 7-[(3S)-(3-amino-3-methoxycarbonyl)propyl]wyosine 5'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74446 CHEBI:74445 2'-O-methylguanosine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74445 CHEBI:74447 5-methyluridine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74447 CHEBI:74449 N(6)-methyladenosine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74449 CHEBI:74442 (23Z,26Z,29Z,32Z,35Z)-3-oxooctatriacontapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74442 CHEBI:74444 7-[(3S)-(3-amino-3-methoxycarbonyl)propyl]wyosine 5'-phosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74444 CHEBI:74443 5,6-dihydrouridine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74443 CHEBI:74457 N-tetracosenoylsphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74457 CHEBI:25401 monomethoxyflavone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25401 CHEBI:25400 monoiodotyrosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25400 CHEBI:74459 (R)-3-hydroxypalmitoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74459 CHEBI:25405 monophosphoglyceric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25405 PR:000012621 progesterone receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000012621 PR|nuclear receptor subfamily 3 group C member 3|NR3C3|PGR A protein that is a translation product of the human PGR gene or a 1:1 ortholog thereof. CHEBI:25409 monoterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25409 CHEBI:74451 (R)-3-hydroxylauroyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74451 CHEBI:25408 monoterpene ketone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25408 CHEBI:74450 N-(15Z)-tetracosenoylsphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74450 CHEBI:74452 NMNH biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74452 UBERON:0002894 olfactory cortex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002894 olfactory areas|archeocortex|olfactory lobe|archaeocortex Aggregate brain region defined as those areas of cerebral cortex receiving direct synaptic input from the olfactory bulb (Price, 1973). It usually includes the piriform cortex and sometimes other areas. CHEBI:74455 5-methylaminomethyl-2-thiouridine 5'-monophosphate zwitterion residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74455 UBERON:0002893 nucleus of lateral olfactory tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002893 nucleus of tractus olfactorius lateralis|lateral olfactory tract nucleus|nucleus of the lateral olfactory tract|nucleus of the lateral olfactory tract (ganser)|nucleus striae olfactoriae lateralis|NLOT|nucleus of the olfactory tract CHEBI:74454 5-aminomethyl-2-thiouridine 5'-monophosphate zwitterion residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74454 GO:0072298 regulation of metanephric glomerulus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072298 Any process that modulates the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros. GO:0072297 specification of metanephric proximal tubule identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072297 The process in which the proximal tubule of the metanephric nephron acquires its identity. GO:0072296 specification of metanephric loop of Henle identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072296 specification of metanephric intermediate tubule identity The process in which the loop of Henle of the metanephric nephron acquires its identity. GO:0072295 specification of metanephric distal tubule identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072295 The process in which the distal tubule of the metanephric nephron acquires its identity. CHEBI:50498 vaccenate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50498 GO:0072294 specification of metanephric connecting tubule identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072294 The process in which the connecting tubule of the metanephric nephron acquires its identity. GO:0072293 specification of metanephric nephron tubule identity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072293 The process in which the tubules arranged along the proximal/distal axis of the metanephric nephron acquire their identity. GO:0072292 epithelial cell migration involved in metanephric proximal tubule morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072292 The orderly movement of epithelial cells within a renal tubule that contributes to metanephric proximal tubule morphogenesis. GO:0072291 epithelial cell migration involved in metanephric distal tubule morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072291 The orderly movement of epithelial cells within a renal tubule that contributes to metanephric distal tubule morphogenesis. GO:0072290 epithelial cell migration involved in metanephric nephron tubule morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072290 The orderly movement of epithelial cells within a renal tubule that contributes to metanephric nephron tubule morphogenesis. CHEBI:132525 oligosaccharide-(1->4)-N-acetyl-beta-D-glucosamine-(1->4)-N-acetyl-alpha-D-glucosamine 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132525 GO:1900077 negative regulation of cellular response to insulin stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900077 inhibition of cellular response to insulin stimulus|down regulation of cellular response to insulin stimulus|downregulation of cellular response to insulin stimulus|down-regulation of cellular response to insulin stimulus Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to insulin stimulus. CHEBI:132529 N(4)-(oligosaccharide-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl)-L-asparagine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132529 GO:1900076 regulation of cellular response to insulin stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900076 Any process that modulates the frequency, rate or extent of cellular response to insulin stimulus. GO:1900079 regulation of arginine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900079 regulation of arginine synthesis|regulation of arginine formation|regulation of arginine biosynthesis|regulation of arginine anabolism Any process that modulates the frequency, rate or extent of arginine biosynthetic process. GO:1900078 positive regulation of cellular response to insulin stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900078 up-regulation of cellular response to insulin stimulus|upregulation of cellular response to insulin stimulus|up regulation of cellular response to insulin stimulus|activation of cellular response to insulin stimulus Any process that activates or increases the frequency, rate or extent of cellular response to insulin stimulus. GO:1900084 regulation of peptidyl-tyrosine autophosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900084 regulation of receptor tyrosine kinase autophosphorylation|regulation of tyrosine autophosphorylation Any process that modulates the frequency, rate or extent of peptidyl-tyrosine autophosphorylation. GO:1900083 obsolete regulation of Sertoli cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900083 regulation of Sertoli cell proliferation OBSOLETE. Any process that modulates the frequency, rate or extent of Sertoli cell proliferation. GO:1900086 positive regulation of peptidyl-tyrosine autophosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900086 upregulation of tyrosine autophosphorylation|up regulation of peptidyl-tyrosine autophosphorylation|activation of peptidyl-tyrosine autophosphorylation|up-regulation of receptor tyrosine kinase autophosphorylation|activation of receptor tyrosine kinase autophosphorylation|up-regulation of tyrosine autophosphorylation|activation of tyrosine autophosphorylation|positive regulation of receptor tyrosine kinase autophosphorylation|up-regulation of peptidyl-tyrosine autophosphorylation|up regulation of receptor tyrosine kinase autophosphorylation|positive regulation of tyrosine autophosphorylation|up regulation of tyrosine autophosphorylation|upregulation of peptidyl-tyrosine autophosphorylation|upregulation of receptor tyrosine kinase autophosphorylation Any process that activates or increases the frequency, rate or extent of peptidyl-tyrosine autophosphorylation. CHEBI:132520 alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol)(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132520 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900085 down-regulation of peptidyl-tyrosine autophosphorylation|down-regulation of receptor tyrosine kinase autophosphorylation|negative regulation of receptor tyrosine kinase autophosphorylation|inhibition of peptidyl-tyrosine autophosphorylation|negative regulation of tyrosine autophosphorylation|down-regulation of tyrosine autophosphorylation|downregulation of receptor tyrosine kinase autophosphorylation|down regulation of receptor tyrosine kinase autophosphorylation|down regulation of peptidyl-tyrosine autophosphorylation|downregulation of tyrosine autophosphorylation|downregulation of peptidyl-tyrosine autophosphorylation|down regulation of tyrosine autophosphorylation|inhibition of receptor tyrosine kinase autophosphorylation|inhibition of tyrosine autophosphorylation Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-tyrosine autophosphorylation. GO:1900080 positive regulation of arginine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900080 positive regulation of arginine anabolism|up regulation of arginine anabolism|positive regulation of arginine synthesis|up regulation of arginine synthesis|positive regulation of arginine formation|up regulation of arginine biosynthesis|up regulation of arginine biosynthetic process|up regulation of arginine formation|activation of arginine biosynthetic process|activation of arginine biosynthesis|positive regulation of arginine biosynthesis|upregulation of arginine anabolism|upregulation of arginine synthesis|upregulation of arginine formation|up-regulation of arginine biosynthetic process|up-regulation of arginine anabolism|up-regulation of arginine biosynthesis|activation of arginine anabolism|up-regulation of arginine synthesis|activation of arginine synthesis|up-regulation of arginine formation|activation of arginine formation|upregulation of arginine biosynthesis|upregulation of arginine biosynthetic process Any process that activates or increases the frequency, rate or extent of arginine biosynthetic process. CHEBI:132522 alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol)(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132522 CHEBI:132521 alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol)(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132521 GO:1900082 negative regulation of arginine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900082 down regulation of arginine breakdown|downregulation of arginine catabolic process|inhibition of arginine breakdown|downregulation of arginine catabolism|down regulation of arginine catabolic process|inhibition of arginine catabolic process|down-regulation of arginine catabolism|negative regulation of arginine catabolism|down-regulation of arginine degradation|negative regulation of arginine degradation|inhibition of arginine catabolism|down-regulation of arginine breakdown|negative regulation of arginine breakdown|downregulation of arginine degradation|down-regulation of arginine catabolic process|down regulation of arginine degradation|inhibition of arginine degradation|downregulation of arginine breakdown|down regulation of arginine catabolism Any process that stops, prevents or reduces the frequency, rate or extent of arginine catabolic process. GO:1900081 regulation of arginine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900081 regulation of arginine catabolism|regulation of arginine degradation|regulation of arginine breakdown Any process that modulates the frequency, rate or extent of arginine catabolic process. CHEBI:132523 alpha-D-Glc-(1->2)-alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol)(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132523 CHEBI:50492 thiocarbonyl compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50492 CHEBI:50491 haloalkyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50491 GO:0072299 negative regulation of metanephric glomerulus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072299 Any process that decreases the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros. GO:0072287 metanephric distal tubule morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072287 The process in which the anatomical structures of a metanephric distal tubule are generated and organized. The metanephric distal tubule is a metanephric nephron tubule that begins at the macula densa and extends to the metanephric connecting tubule. GO:0072286 metanephric connecting tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072286 metanephric connecting duct development The process whose specific outcome is the progression of the metanephric connecting tubule over time, from its formation to the mature structure. The metanephric connecting tubule is a tubular segment of the metanephric nephron; it connects the distal convoluted tubule to the collecting duct in the metanephros. GO:0072285 mesenchymal to epithelial transition involved in metanephric renal vesicle formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072285 A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephric renal vesicle. GO:0072284 metanephric S-shaped body morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072284 The process in which the metanephric S-shaped body is generated and organized. The metanephric S-shaped body is the successor of the metanephric comma-shaped body that contributes to the morphogenesis of a nephron in the metanephros. GO:0072283 metanephric renal vesicle morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072283 The process in which the anatomical structures of the metanephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the metanephric nephron epithelium, and is formed by the condensation of mesenchymal cells. GO:0072282 metanephric nephron tubule morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072282 The process in which the anatomical structures of a metanephric nephron tubule are generated and organized. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros. GO:0072281 mesenchymal stem cell differentiation involved in metanephric nephron morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072281 The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephronin the metanephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells. GO:0072280 establishment of planar polarity involved in metanephric nephron morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072280 establishment of planar cell polarity involved in metanephric nephron morphogenesis Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron in the metanephros. CHEBI:132537 N(4)-(alpha-D-Glc-(1->2)-alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc)-L-asparaginyl residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132537 CHEBI:132539 fatty acid 20:4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132539 CHEBI:132538 fatty acid 20:1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132538 GO:1900088 regulation of inositol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900088 regulation of inositol synthesis|regulation of inositol formation|regulation of inositol biosynthesis|regulation of vitamin Bh biosynthetic process|regulation of vitamin Bh biosynthesis|regulation of myo-inositol biosynthetic process|regulation of myo-inositol biosynthesis|regulation of inositol anabolism Any process that modulates the frequency, rate or extent of inositol biosynthetic process. CHEBI:49496 gold(3+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49496 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900087 upregulation of G1/S transition of mitotic cell cycle|up regulation of G1/S transition of mitotic cell cycle|activation of G1/S transition of mitotic cell cycle|up-regulation of G1/S transition of mitotic cell cycle Any signalling pathway that increases or activates a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle. GO:1900089 negative regulation of inositol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900089 down-regulation of vitamin Bh biosynthetic process|downregulation of inositol synthesis|negative regulation of vitamin Bh biosynthetic process|down-regulation of vitamin Bh biosynthesis|negative regulation of vitamin Bh biosynthesis|down regulation of inositol anabolism|down-regulation of myo-inositol biosynthetic process|down-regulation of myo-inositol biosynthesis|negative regulation of myo-inositol biosynthesis|negative regulation of myo-inositol biosynthetic process|downregulation of inositol formation|inhibition of inositol biosynthetic process|down regulation of inositol synthesis|inhibition of inositol anabolism|down regulation of inositol formation|inhibition of inositol biosynthesis|inhibition of inositol synthesis|inhibition of vitamin Bh biosynthesis|inhibition of vitamin Bh biosynthetic process|inhibition of myo-inositol biosynthetic process|inhibition of inositol formation|inhibition of myo-inositol biosynthesis|down regulation of inositol biosynthetic process|down regulation of inositol biosynthesis|negative regulation of inositol anabolism|down regulation of vitamin Bh biosynthesis|down regulation of vitamin Bh biosynthetic process|down-regulation of inositol anabolism|downregulation of inositol biosynthetic process|downregulation of inositol biosynthesis|down regulation of myo-inositol biosynthesis|down regulation of myo-inositol biosynthetic process|negative regulation of inositol synthesis|downregulation of vitamin Bh biosynthesis|down-regulation of inositol synthesis|downregulation of vitamin Bh biosynthetic process|downregulation of myo-inositol biosynthesis|downregulation of myo-inositol biosynthetic process|negative regulation of inositol formation|down-regulation of inositol formation|downregulation of inositol anabolism|negative regulation of inositol biosynthesis|down-regulation of inositol biosynthesis|down-regulation of inositol biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of inositol biosynthetic process. GO:1900095 regulation of dosage compensation by inactivation of X chromosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900095 regulation of chromosome inactivation|regulation of Barr body formation|regulation of X chromosome inactivation Any process that modulates the frequency, rate or extent of dosage compensation, by inactivation of X chromosome. GO:1900094 regulation of transcription from RNA polymerase II promoter involved in determination of left/right symmetry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900094 regulation of global transcription from Pol II promoter of determination of left/right symmetry|regulation of transcription from RNA polymerase II promoter, global of determination of left/right symmetry|regulation of gene-specific transcription from RNA polymerase II promoter of determination of left/right asymmetry|global transcription regulation from Pol II promoter of determination of left/right asymmetry|global transcription regulation from Pol II promoter of determination of left/right symmetry|regulation of gene-specific transcription from RNA polymerase II promoter of determination of left/right symmetry|regulation of transcription from RNA polymerase II promoter, global of determination of left/right asymmetry|regulation of transcription from Pol II promoter of determination of left/right symmetry|regulation of global transcription from Pol II promoter of determination of left/right asymmetry|regulation of transcription from RNA polymerase II promoter of determination of left/right asymmetry|regulation of transcription from RNA polymerase II promoter of determination of left/right symmetry|regulation of transcription from Pol II promoter of determination of left/right asymmetry Any regulation of transcription from RNA polymerase II promoter that is involved in determination of left/right symmetry. GO:1900097 positive regulation of dosage compensation by inactivation of X chromosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900097 upregulation of dosage compensation, by inactivation of X chromosome|up regulation of X chromosome inactivation|upregulation of Barr body formation|positive regulation of X chromosome inactivation|up regulation of chromosome inactivation|positive regulation of chromosome inactivation|activation of X chromosome inactivation|up-regulation of dosage compensation, by inactivation of X chromosome|activation of dosage compensation, by inactivation of X chromosome|activation of chromosome inactivation|up regulation of Barr body formation|up-regulation of X chromosome inactivation|positive regulation of Barr body formation|up-regulation of chromosome inactivation|activation of Barr body formation|up regulation of dosage compensation, by inactivation of X chromosome|upregulation of X chromosome inactivation|upregulation of chromosome inactivation|up-regulation of Barr body formation Any process that activates or increases the frequency, rate or extent of dosage compensation, by inactivation of X chromosome. GO:1900096 negative regulation of dosage compensation by inactivation of X chromosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900096 down regulation of chromosome inactivation|down regulation of dosage compensation, by inactivation of X chromosome|inhibition of dosage compensation, by inactivation of X chromosome|downregulation of X chromosome inactivation|inhibition of Barr body formation|downregulation of chromosome inactivation|down regulation of Barr body formation|negative regulation of X chromosome inactivation|down-regulation of X chromosome inactivation|downregulation of Barr body formation|negative regulation of chromosome inactivation|down-regulation of chromosome inactivation|down-regulation of dosage compensation, by inactivation of X chromosome|inhibition of X chromosome inactivation|down-regulation of Barr body formation|negative regulation of Barr body formation|inhibition of chromosome inactivation|downregulation of dosage compensation, by inactivation of X chromosome|down regulation of X chromosome inactivation Any process that stops, prevents or reduces the frequency, rate or extent of dosage compensation, by inactivation of X chromosome. GO:1900091 regulation of raffinose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900091 regulation of raffinose biosynthesis|regulation of raffinose anabolism|regulation of raffinose synthesis|regulation of raffinose formation Any process that modulates the frequency, rate or extent of raffinose biosynthetic process. GO:1900090 positive regulation of inositol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900090 activation of inositol synthesis|up regulation of inositol biosynthetic process|positive regulation of inositol anabolism|up regulation of inositol biosynthesis|activation of inositol biosynthetic process|positive regulation of inositol biosynthesis|activation of inositol formation|up regulation of inositol anabolism|up regulation of vitamin Bh biosynthesis|up regulation of vitamin Bh biosynthetic process|positive regulation of inositol synthesis|positive regulation of vitamin Bh biosynthetic process|up regulation of myo-inositol biosynthetic process|up regulation of myo-inositol biosynthesis|positive regulation of vitamin Bh biosynthesis|up regulation of inositol synthesis|positive regulation of inositol formation|positive regulation of myo-inositol biosynthetic process|activation of inositol biosynthesis|positive regulation of myo-inositol biosynthesis|up regulation of inositol formation|activation of vitamin Bh biosynthetic process|activation of vitamin Bh biosynthesis|upregulation of inositol anabolism|activation of myo-inositol biosynthesis|activation of myo-inositol biosynthetic process|up-regulation of inositol biosynthetic process|up-regulation of inositol biosynthesis|upregulation of inositol synthesis|up-regulation of vitamin Bh biosynthetic process|up-regulation of vitamin Bh biosynthesis|up-regulation of myo-inositol biosynthetic process|up-regulation of myo-inositol biosynthesis|upregulation of inositol formation|up-regulation of inositol anabolism|upregulation of inositol biosynthetic process|upregulation of inositol biosynthesis|upregulation of vitamin Bh biosynthetic process|upregulation of vitamin Bh biosynthesis|up-regulation of inositol synthesis|upregulation of myo-inositol biosynthesis|upregulation of myo-inositol biosynthetic process|activation of inositol anabolism|up-regulation of inositol formation Any process that activates or increases the frequency, rate or extent of inositol biosynthetic process. GO:1900093 positive regulation of raffinose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900093 up regulation of raffinose formation|activation of raffinose anabolism|up-regulation of raffinose biosynthetic process|up-regulation of raffinose biosynthesis|positive regulation of raffinose formation|activation of raffinose biosynthetic process|activation of raffinose synthesis|up-regulation of raffinose anabolism|activation of raffinose formation|activation of raffinose biosynthesis|up-regulation of raffinose synthesis|positive regulation of raffinose biosynthesis|up-regulation of raffinose formation|up regulation of raffinose biosynthetic process|up regulation of raffinose biosynthesis|upregulation of raffinose anabolism|upregulation of raffinose synthesis|upregulation of raffinose formation|upregulation of raffinose biosynthetic process|upregulation of raffinose biosynthesis|up regulation of raffinose anabolism|positive regulation of raffinose anabolism|up regulation of raffinose synthesis|positive regulation of raffinose synthesis Any process that activates or increases the frequency, rate or extent of raffinose biosynthetic process. GO:1900092 negative regulation of raffinose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900092 negative regulation of raffinose synthesis|down-regulation of raffinose synthesis|negative regulation of raffinose formation|down-regulation of raffinose formation|down-regulation of raffinose biosynthesis|negative regulation of raffinose biosynthesis|down-regulation of raffinose biosynthetic process|inhibition of raffinose anabolism|inhibition of raffinose synthesis|downregulation of raffinose biosynthetic process|inhibition of raffinose formation|down regulation of raffinose anabolism|downregulation of raffinose biosynthesis|downregulation of raffinose anabolism|down regulation of raffinose biosynthetic process|down regulation of raffinose biosynthesis|down regulation of raffinose synthesis|inhibition of raffinose biosynthetic process|down regulation of raffinose formation|downregulation of raffinose synthesis|downregulation of raffinose formation|inhibition of raffinose biosynthesis|negative regulation of raffinose anabolism|down-regulation of raffinose anabolism Any process that stops, prevents or reduces the frequency, rate or extent of raffinose biosynthetic process. GO:0072289 metanephric nephron tubule formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072289 The developmental process pertaining to the initial formation of a metanephric nephron tubule from unspecified parts. A metanephric nephron tubule is an epithelial tube that is part of a nephron in the metanephros. GO:0072288 metanephric proximal tubule morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072288 The process in which the anatomical structures of a metanephric proximal tubule are generated and organized. The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology. CHEBI:50477 butyrate ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50477 CHEBI:132503 fatty acid 18:4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132503 CHEBI:132506 N-arachidonoyltaurine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132506 CHEBI:132505 N-tetracosanoyltaurine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132505 GO:1900099 negative regulation of plasma cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900099 down-regulation of plasma cell differentiation|down regulation of plasma cell development|downregulation of plasma cell development|inhibition of plasma cell differentiation|down-regulation of plasma cell development|negative regulation of plasma cell development|down regulation of plasma cell differentiation|downregulation of plasma cell differentiation|inhibition of plasma cell development Any process that stops, prevents or reduces the frequency, rate or extent of plasma cell differentiation. CHEBI:132508 N-[15(S)-hydroperoxy-(5Z,8Z,11Z,13E)-icosatetraenoyl]taurine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132508 GO:1900098 regulation of plasma cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900098 regulation of plasma cell development Any process that modulates the frequency, rate or extent of plasma cell differentiation. CHEBI:132507 N-[12(S)-hydroperoxy-(5Z,8Z,10E,14Z)-icosatetraenoyl]taurine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132507 CHEBI:132502 fatty acid 18:3 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132502 CHEBI:50471 primary arylamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50471 CHEBI:50467 trans-2-decenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50467 CHEBI:50465 2-decenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50465 CHEBI:50469 EC 3.1.1.4 (phospholipase A2) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50469 CHEBI:132515 alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol)(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132515 CHEBI:132517 alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol)(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132517 CHEBI:132516 alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol)(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132516 CHEBI:132519 alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol)(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132519 CHEBI:132511 alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol)(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132511 CHEBI:132510 alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc(PP-Dol)(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132510 CHEBI:50464 cis-vaccenic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50464 CHEBI:49468 silver(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49468 UBERON:0002834 cervical dorsal root ganglion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002834 cervical dorsal root ganglion|cervical spinal ganglion UBERON:0002835 thoracic dorsal root ganglion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002835 dorsal root ganglion of thorax|thorax ganglion spinalis|thorax dorsal root ganglion|thoracic spinal ganglion|thoracic dorsal root ganglion|ganglion of dorsal root of thorax|thorax ganglion of dorsal root|ganglion spinalis of thorax A dorsal root ganglion that is part of a thorax [Automatically generated definition]. CHEBI:25491 nematicide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25491 CHEBI:50452 6-hydroxy-3-isopropenylheptanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50452 CHEBI:50451 6-hydroxy-3,7-dimethyloctanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50451 CHEBI:50450 1-naphthylamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50450 UBERON:0002827 vestibulocochlear ganglion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002827 statoacoustic ganglia|auditory ganglion|acoustico-vestibular VIII ganglion|SAG|acoustic ganglion VIII|acoustic ganglion|vestibulocochlear VIII ganglion|ganglion VIII|nucleus nervi oculomotorii, pars ventralis|statoacoustic (VIII) ganglion|gVIII|nucleus nervi oculomotorii ventrolateralis|vestibulocochlear ganglia|statoacoustic VIII ganglion|auditory ganglion|statoacoustic ganglion the group of neuron cell bodies associated with the eighth cranial nerve during embryogenesis; splits in later development to form the cochlear and vestibular ganglia CHEBI:50446 3-(hydroxyamino)phenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50446 CHEBI:50445 EC 3.5.4.4 (adenosine deaminase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50445 UBERON:0002829 dorsal cochlear nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002829 posterior cochlear nucleus|dorsal division of cochlear nucleus|nucleus cochlearis posterior|nucleus cochlearis dorsalis|dorsal coclear nucleus|DCo|tuberculum acousticum|dorsal cochlear nucleus The dorsal cochlear nucleus (DCN, also known as the 'tuberculum acousticum'), is a cortex-like structure on the dorso-lateral surface of the brainstem. Along with the ventral cochlear nucleus, it forms the cochlear nucleus, where all auditory nerve fibers from the cochlea form their first synapses. [WP,unvetted]. UBERON:0002828 ventral cochlear nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002828 nucleus acustici accessorici|ventral cochlear nucleus|nucleus cochlearis anterior|nucleus cochlearis ventralis|c1281209|ventral cochlear nuclei|ventral division of cochlear nucleus|accessory cochlear nucleus|ventral coclear nucleus|VCo|anterior cochlear nucleus The ventral cochlear nucleus (or anterior, or accessory), placed between the two divisions of the cochlear nerve, is on the ventral aspect of the inferior peduncle. Composed of several regions of distinct cell types, this nucleus serves primarily as a relay station for ascending auditory information. Bushy cells in the anterior ventral cochlear nucleus (AVCN), which receive end bulbs of held from auditory nerve fibers, project to the superior olivary complex through the trapezoid body and intermediate acoustic stria. Other cell types project to the lateral lemniscus and the inferior colliculus directly. [WP,unvetted]. CHEBI:50448 naphthylamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50448 UBERON:0002824 vestibular ganglion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002824 vestibulocochlear VIII ganglion vestibular component|vestibulocochlear ganglion vestibular component|nucleus nervi oculomotorii, pars medialis|Scarpa's ganglion|vestibular part of vestibulocochlear ganglion The ganglion of the vestibular nerve. It contains the cell bodies of the bipolar primary afferent neurons whose peripheral processes form synaptic contact with hair cells of the vestibular sensory end organs[WP,unvetted]. Distributed to the maculae of the utricle and saccule and to the ampullary crests of the semicircular ducts. The vestibular fibers arise in bipolar cells in the vestibular ganglion in the internal acoustic meatus. CHEBI:50447 (S)-carnitinamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50447 CHEBI:50442 N-substituted cadaverine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50442 CHEBI:50441 N-substituted diamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50441 CHEBI:25479 naphthalenone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25479 CHEBI:25478 naphthalenesulfonate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25478 CHEBI:25477 naphthalenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25477 UBERON:0002812 left cerebral hemisphere biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002812 left hemisphere A cerebral hemisphere that is in the left side of a brain. UBERON:0002811 left frontal lobe biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002811 A frontal cortex that is part of a left cerebral hemisphere. OBO:pr#lacks_part biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/pr#lacks_part lacks_part CHEBI:50436 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50436 UBERON:0002813 right cerebral hemisphere biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002813 right hemisphere A cerebral hemisphere that is in the right side of a brain. UBERON:0002805 right limbic lobe biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002805 A limbic lobe that is part of a right cerebral hemisphere. UBERON:0002804 left limbic lobe biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002804 A limbic lobe that is part of a left cerebral hemisphere. CHEBI:50427 platelet aggregation inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50427 UBERON:0002803 right parietal lobe biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002803 Parietal lobe of the right hemisphere of the brain CHEBI:50425 inorganic disulfide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50425 UBERON:0002802 left parietal lobe biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002802 Parietal lobe of the left hemisphere of the brain CHEBI:25482 naphthoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25482 CHEBI:25481 naphthoquinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25481 CHEBI:50429 (Z)-glutaconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50429 UBERON:0002809 right temporal lobe biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002809 A temporal lobe that is part of a right cerebral hemisphere. UBERON:0002808 left temporal lobe biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002808 A temporal lobe that is part of a left cerebral hemisphere. CHEBI:49432 5-hydroxyectoine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49432 CHEBI:25483 naphthoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25483 UBERON:0002810 right frontal lobe biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002810 A frontal cortex that is part of a right cerebral hemisphere. GO:0072210 metanephric nephron development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072210 The process whose specific outcome is the progression of a nephron in the metanephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney. GO:0047254 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047254 RHEA:15541|EC:2.4.1.202|MetaCyc:2.4.1.202-RXN UDP-glucose:2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucosyltransferase activity|uridine diphosphoglucose-2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-glucosyltransferase activity|UDPglucose:2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucosyltransferase activity Catalysis of the reaction: 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one + UDP-D-glucose = 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucoside + UDP. GO:0047253 alpha-1,6-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047253 EC:2.4.1.201|RHEA:19945|MetaCyc:2.4.1.201-RXN mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase activity|mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyl-transferase activity|UDP-N-acetyl-D-glucosamine:2,6-bis(N-acetyl-beta-D-glucosaminyl)-alpha-D-mannosyl-glycoprotein 4-beta-N-acetyl-D-glucosaminyltransferase activity|N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase VI activity|uridine diphosphoacetylglucosamine-glycopeptide beta-1->4-acetylglucosaminyltransferase VI activity|N-acetylglucosaminyltransferase VI activity|uridine diphosphoacetylglucosamine-glycopeptide beta-1->4-acetylglucosaminyltransferase VI|alpha-1,6-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase activity Catalysis of the reaction: N-acetyl-beta-D-glucosaminyl-1,6-beta-D-(N-acetyl-B-glucosaminyl-1,2)-beta-D-mannosyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,6-beta-D-(N-acetyl-D-glucosaminyl-1,2-beta)-(N-acetyl-D-glucosaminyl-1,4-beta)-D-mannosyl-R + UDP. GO:0047252 beta-mannosylphosphodecaprenol-mannooligosaccharide 6-mannosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047252 EC:2.4.1.199|MetaCyc:2.4.1.199-RXN mannosylphospholipid-methylmannoside alpha-1,6-mannosyltransferase activity|beta-D-mannosylphosphodecaprenol:1,6-alpha-D-mannosyloligosaccharide 1,6-alpha-D-mannosyltransferase activity Catalysis of the reaction: (1->6)-alpha-D-mannosyloligosaccharide + beta-D-mannosylphosphodecaprenol = (1->6)-alpha-D-mannosyl-(1->6)-alpha-D-mannosyl-oligosaccharide + decaprenol phosphate. GO:0047251 thiohydroximate beta-D-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047251 MetaCyc:2.4.1.195-RXN|EC:2.4.1.195|RHEA:13757 desulfoglucosinolate-uridine diphosphate glucosyltransferase activity|UDP-glucose:thiohydroximate S-beta-D-glucosyltransferase activity|N-hydroxythioamide S-beta-glucosyltransferase activity|thiohydroximate glucosyltransferase activity|uridine diphosphoglucose-thiohydroximate glucosyltransferase activity|UDP-glucose:N-hydroxy-2-phenylethanethioamide S-beta-D-glucosyltransferase activity|thiohydroximate S-glucosyltransferase activity|UDPG:thiohydroximate glucosyltransferase activity Catalysis of the reaction: phenylthioacetohydroximate + UDP-D-glucose = desulfoglucotropeolin + UDP. GO:0047250 4-hydroxybenzoate 4-O-beta-D-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047250 RHEA:15153|MetaCyc:2.4.1.194-RXN|EC:2.4.1.194|KEGG_REACTION:R01304 UDP-glucose:4-(beta-D-glucopyranosyloxy)benzoic acid glucosyltransferase activity|PHB-O-glucosyltransferase activity|UDP-glucose:4-hydroxybenzoate 4-O-beta-D-glucosyltransferase activity|p-hydroxybenzoate glucosyltransferase activity|HBA glucosyltransferase activity|PHB glucosyltransferase activity|uridine diphosphoglucose-4-hydroxybenzoate glucosyltransferase activity|UDPglucose:4-hydroxybenzoate 4-O-beta-D-glucosyltransferase activity Catalysis of the reaction: 4-hydroxybenzoate + UDP-D-glucose = 4-(beta-D-glucosyloxy)benzoate + H(+) + UDP. CL:0002548 fibroblast of cardiac tissue biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002548 cardiac fibroblast A fibroblast that is part of the heart. GO:0047259 glucomannan 4-beta-mannosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047259 MetaCyc:2.4.1.32-RXN|EC:2.4.1.32 glucomannan-synthase activity|GDP-man-beta-mannan mannosyltransferase activity|GDP-mannose:glucomannan 1,4-beta-D-mannosyltransferase activity|glucomannan 4-b-mannosyltransferase activity Catalysis of the reaction: glucomannan(n) + GDP-mannose = glucomannan(n+1) + GDP. GO:0047258 sphingosine beta-galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047258 MetaCyc:2.4.1.23-RXN|RHEA:19485|KEGG_REACTION:R01928|EC:2.4.1.23 UDPgalactose:sphingosine 1-beta-galactotransferase activity|psychosine-UDP galactosyltransferase activity|psychosine-uridine diphosphate galactosyltransferase activity|UDPgalactose:sphingosine O-galactosyl transferase activity|galactosyl-sphingosine transferase activity|uridine diphosphogalactose-sphingosine beta-galactosyltransferase activity|UDP-galactose:sphingosine 1-beta-galactotransferase activity Catalysis of the reaction: sphingosine + UDP-D-galactose = H(+) + psychosine + UDP. GO:0047257 diglucosyl diacylglycerol synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047257 RHEA:19165|MetaCyc:2.4.1.208-RXN|EC:2.4.1.208 monoglucosyl diacylglycerol (1->2) glucosyltransferase activity|diglucosyl diacylglycerol (DGlcDAG) synthase activity|MGlcDAG (1->2) glucosyltransferase activity|UDP-glucose:1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol (1->2) glucosyltransferase activity|DGlcDAG synthase activity Catalysis of the reaction: 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol + UDP-D-glucose = UDP + 1,2-diacyl-3-O-(alpha-D-glucopyranosyl(1,2)-O-alpha-D-glucopyranosyl)-sn-glycerol. GO:0047256 lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047256 RHEA:13905|MetaCyc:2.4.1.206-RXN|EC:2.4.1.206 uridine diphosphoacetylglucosamine-lactosylceramide beta-acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:D-galactosyl-1,4-beta-D-glucosylceramide beta-1,3-acetylglucosaminyltransferase activity|LA2 synthase activity|beta1->3-N-acetylglucosaminyltransferase activity|lactosylceramide beta-acetylglucosaminyltransferase activity Catalysis of the reaction: cytolipin-H + UDP-N-acetyl-D-glucosamine = N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide + UDP. GO:0047255 galactogen 6-beta-galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047255 MetaCyc:2.4.1.205-RXN|EC:2.4.1.205 UDP-galactose:galactogen beta-1,6-D-galactosyltransferase activity|beta-(1,6)-D-galactosyltransferase activity|1,6-D-galactosyltransferase activity|uridine diphosphogalactose-galactogen galactosyltransferase activity|UDPgalactose:galactogen beta-1,6-D-galactosyltransferase activity|galactogen 6beta-galactosyltransferase activity Catalysis of the reaction: galactogen + UDP-galactose = 1,6-beta-D-galctosylgalactogen + UDP. CL:0002540 mesenchymal stem cell of the bone marrow biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002540 A mesenchymal stem cell that is part of the bone marrow. CL:0002541 chorionic membrane mesenchymal stem cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002541 A mesenchymal stem cell of the chorionic membrane. CL:0002543 vein endothelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002543 venous endothelial cell|endothelial cell of vein An endothelial cell that is part of the vein. CL:0002546 embryonic blood vessel endothelial progenitor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002546 An endothelial progenitor cell that participates in angiogenesis during development. GO:0072219 metanephric cortical collecting duct development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072219 The process whose specific outcome is the progression of the metanephric cortical collecting duct over time, from its formation to the mature structure. The metanephric cortical collecting duct is the portion of the metanephric collecting duct that resides in the renal cortex. GO:0072218 metanephric ascending thin limb development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072218 The process whose specific outcome is the progression of a metanephric ascending thin limb over time, from its formation to the mature structure. The metanephric ascending thin limb is a segment of a nephron tubule in the metanephros lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent. GO:0072217 negative regulation of metanephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072217 Any process that decreases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. GO:0072216 positive regulation of metanephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072216 Any process that increases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. GO:0072215 regulation of metanephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072215 Any process that modulates the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine. GO:0072214 metanephric cortex development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072214 The process whose specific outcome is the progression of the metanephric cortex over time, from its formation to the mature structure. The metanephric cortex is the outer region of the metanephros. GO:0072213 metanephric capsule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072213 The process whose specific outcome is the progression of the metanephric capsule over time, from its formation to the mature structure. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. GO:0072212 regulation of transcription from RNA polymerase II promoter involved in metanephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072212 Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the branching morphogenesis by which the metanephros progresses from its initial formation to the mature state. GO:0072211 metanephric pyramids development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072211 metanephric renal medulla development|metanephric kidney pyramid development|metanephric renal pyramid development|metanephric pyramid development The process whose specific outcome is the progression of the metanephric pyramids over time, from their formation to the mature structures. Metanephric pyramids are the conical masses that constitute the renal medulla in a metanephros; they contain the loops of Henle and the medullary collecting ducts. GO:0047265 poly(glycerol-phosphate) alpha-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047265 RHEA:15845|EC:2.4.1.52|MetaCyc:2.4.1.52-RXN UDP-glucose:poly(glycerol-phosphate) alpha-D-glucosyltransferase activity|uridine diphosphoglucose-poly(glycerol-phosphate) alpha-glucosyltransferase activity|UDP glucose-poly(glycerol-phosphate) alpha-glucosyltransferase activity|UDPglucose:poly(glycerol-phosphate) alpha-D-glucosyltransferase activity Catalysis of the reaction: poly(glycerol phosphate) + UDP-D-glucose = alpha-D-glucosylpoly(glycerol phosphate) + UDP. GO:0047264 heteroglycan alpha-mannosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047264 EC:2.4.1.48 heteropolysaccharide alpha-mannosyltransferase activity|GDP-mannose:heteroglycan 2-(or 3-)-alpha-D-mannosyltransferase activity|guanosine diphosphomannose-heteroglycan alpha-mannosyltransferase activity|GDP mannose alpha-mannosyltransferase activity Catalysis of the reaction: heteroglycan + GDP-mannose = alpha-D-mannosylheteroglycan + GDP. GO:0047263 N-acylsphingosine galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047263 EC:2.4.1.47|Reactome:R-HSA-6785933|MetaCyc:2.4.1.47-RXN|RHEA:13093 UDP-galactose:N-acylsphingosine D-galactosyltransferase activity|uridine diphosphogalactose-acylsphingosine galactosyltransferase activity|UDP galactose-N-acylsphingosine galactosyltransferase activity|UDPgalactose:N-acylsphingosine D-galactosyltransferase activity Catalysis of the reaction: ceramide + UDP-galactose = D-galactosylceramide + UDP. GO:0047262 polygalacturonate 4-alpha-galacturonosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047262 EC:2.4.1.43|RHEA:13573|MetaCyc:2.4.1.43-RXN UDP galacturonate-polygalacturonate alpha-galacturonosyltransferase activity|uridine diphosphogalacturonate-polygalacturonate alpha-galacturonosyltransferase activity|UDP-D-galacturonate:1,4-alpha-poly-D-galacturonate 4-alpha-D-galacturonosyltransferase activity Catalysis of the reaction: UDP-D-galacturonate + 1,4-alpha-D-galacturonosyl(n) = 1,4-alpha-D-galacturonosyl(n+1) + UDP. GO:0047261 steroid N-acetylglucosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047261 MetaCyc:2.4.1.39-RXN|KEGG_REACTION:R04451|RHEA:14153|EC:2.4.1.39 uridine diphosphoacetylglucosamine-steroid acetylglucosaminyltransferase activity|hydroxy steroid acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:estradiol-17alpha-3-D-glucuronoside 17alpha-N-acetylglucosaminyltransferase activity|steroid acetylglucosaminyltransferase activity Catalysis of the reaction: estradiol-17alpha 3-D-glucuronoside + UDP-N-acetyl-alpha-D-glucosamine = 17alpha-(N-acetyl-D-glucosaminyl)-estradiol 3-D-glucuronoside + H(+) + UDP. GO:1900008 obsolete negative regulation of extrachromosomal rDNA circle accumulation involved in replicative cell aging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900008 negative regulation of extrachromosomal ribosomal DNA circle accumulation during replicative cell aging|negative regulation of extrachromosomal rDNA circle accumulation during replicative cell ageing|down regulation of extrachromosomal rDNA circle accumulation involved in replicative cell aging|down regulation of extrachromosomal rDNA circle accumulation during replicative cell aging|down regulation of extrachromosomal ribosomal DNA circle accumulation during replicative cell aging|down regulation of extrachromosomal rDNA circle accumulation during replicative cell ageing|negative regulation of extrachromosomal rDNA circle accumulation during replicative cell aging OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of extrachromosomal rDNA circle accumulation involved in replicative cell aging. GO:0047260 alpha,alpha-trehalose-phosphate synthase (GDP-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047260 EC:2.4.1.36|RHEA:14605|MetaCyc:2.4.1.36-RXN GDP-glucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase activity|GDP-glucose-glucosephosphate glucosyltransferase activity|GDPglucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase activity|GDPglucose-glucose-phosphate glucosyltransferase activity|trehalose phosphate synthase (GDP-forming) activity|guanosine diphosphoglucose-glucose phosphate glucosyltransferase activity Catalysis of the reaction: GDP-D-glucose + glucose-6-phosphate = alpha,alpha-trehalose 6-phosphate + GDP. GO:0106202 obsolete translocase activity acting on amino acids and peptides linked to a decarboxylation reaction biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106202 EC:7.4.4.- OBSOLETE. Catalysis of the translocation of amno acids and peptides linked to a decarboxylation reaction. GO:1900007 obsolete regulation of extrachromosomal rDNA circle accumulation involved in replicative cell aging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900007 regulation of extrachromosomal ribosomal DNA circle accumulation during replicative cell aging|regulation of extrachromosomal rDNA circle accumulation during replicative cell aging|regulation of extrachromosomal rDNA circle accumulation during replicative cell ageing OBSOLETE. Any process that modulates the frequency, rate or extent of extrachromosomal rDNA circle accumulation involved in replicative cell aging. GO:0106201 obsolete translocase activity acting on amino acids and peptides linked to the hydrolysis of a diphosphate biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106201 EC:7.4.3.- OBSOLETE. Catalysis of the translocation of amino acids and peptides linked to the hydrolysis of a diphosphate. GO:0106200 obsolete translocase activity acting on amio acids and peptides linked to the hydrolysis of a nucleoside triphosphate biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106200 EC:7.4.2.- OBSOLETE. Catalysis of the translocation of amino acids and peptides linked to the hydrolysis of a nucleoside triphosphate. GO:1900009 obsolete positive regulation of extrachromosomal rDNA circle accumulation involved in replicative cell aging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900009 up regulation of extrachromosomal rDNA circle accumulation involved in replicative cell aging|positive regulation of extrachromosomal ribosomal DNA circle accumulation during replicative cell aging|positive regulation of extrachromosomal rDNA circle accumulation during replicative cell ageing|up regulation of extrachromosomal ribosomal DNA circle accumulation during replicative cell aging|up regulation of extrachromosomal rDNA circle accumulation during replicative cell ageing|up regulation of extrachromosomal rDNA circle accumulation during replicative cell aging|positive regulation of extrachromosomal rDNA circle accumulation during replicative cell aging OBSOLETE. Any process that activates or increases the frequency, rate or extent of extrachromosomal rDNA circle accumulation involved in replicative cell aging. GO:1900004 negative regulation of serine-type endopeptidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900004 negative regulation of blood coagulation factor activity|down regulation of blood coagulation factor activity|down regulation of serine-type endopeptidase activity Any process that stops, prevents or reduces the frequency, rate or extent of serine-type endopeptidase activity. CL:0002559 hair follicle cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002559 An animal cell that is part of a hair follicle. GO:1900003 regulation of serine-type endopeptidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900003 regulation of blood coagulation factor activity Any process that modulates the frequency, rate or extent of serine-type endopeptidase activity. GO:1900006 positive regulation of dendrite development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900006 up regulation of dendrite development Any process that activates or increases the frequency, rate or extent of dendrite development. GO:1900005 positive regulation of serine-type endopeptidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900005 positive regulation of blood coagulation factor activity|up regulation of serine-type endopeptidase activity|up regulation of blood coagulation factor activity Any process that activates or increases the frequency, rate or extent of serine-type endopeptidase activity. GO:0047269 poly(ribitol-phosphate) N-acetylglucosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047269 RHEA:21012|EC:2.4.1.70|MetaCyc:2.4.1.70-RXN UDP-N-acetyl-D-glucosamine:poly(ribitol-phosphate) N-acetyl-D-glucosaminyltransferase activity|UDP acetylglucosamine-poly(ribitol phosphate) acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-poly(ribitol phosphate) acetylglucosaminyltransferase activity Catalysis of the reaction: poly(ribitol phosphate) + UDP-N-acetyl-D-glucosamine = N-acetyl-D-glucosaminyl-poly(ribitol phosphate) + UDP. GO:1900000 regulation of anthocyanin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900000 regulation of anthocyanin breakdown|regulation of anthocyanin catabolism|regulation of anthocyanin degradation Any process that modulates the frequency, rate or extent of anthocyanin catabolic process. GO:0047268 galactinol-raffinose galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047268 EC:2.4.1.67|RHEA:20776|MetaCyc:2.4.1.67-RXN stachyose synthetase activity|alpha-D-(1->3)-galactosyl-myo-inositol:raffinose galactosyltransferase activity Catalysis of the reaction: raffinose + 1-alpha-D-galactosyl-myo-inositol = stachyose + myo-inositol. GO:1900002 positive regulation of anthocyanin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900002 up regulation of anthocyanin degradation|positive regulation of anthocyanin degradation|up regulation of anthocyanin breakdown|positive regulation of anthocyanin breakdown|up regulation of anthocyanin catabolic process|positive regulation of anthocyanin catabolism|up regulation of anthocyanin catabolism Any process that activates or increases the frequency, rate or extent of anthocyanin catabolic process. GO:0047267 undecaprenyl-phosphate mannosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047267 EC:2.4.1.54 GDP mannose-undecaprenyl phosphate mannosyltransferase activity|GDP-mannose:undecaprenyl-phosphate D-mannosyltransferase activity|GDP-D-mannose:lipid phosphate transmannosylase activity|guanosine diphosphomannose-undecaprenyl phosphate mannosyltransferase activity Catalysis of the reaction: GDP-mannose + undecaprenyl phosphate = GDP + D-mannosyl-1-phosphoundecaprenol. GO:1900001 negative regulation of anthocyanin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900001 down regulation of anthocyanin breakdown|negative regulation of anthocyanin degradation|down regulation of anthocyanin catabolic process|negative regulation of anthocyanin breakdown|negative regulation of anthocyanin catabolism|down regulation of anthocyanin degradation|down regulation of anthocyanin catabolism Any process that stops, prevents or reduces the frequency, rate or extent of anthocyanin catabolic process. GO:0047266 poly(ribitol-phosphate) beta-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047266 EC:2.4.1.53|RHEA:10068|MetaCyc:2.4.1.53-RXN uridine diphosphoglucose-poly(ribitol-phosphate) beta-glucosyltransferase activity|UDP glucose-poly(ribitol-phosphate) beta-glucosyltransferase activity|UDPglucose:poly(ribitol-phosphate) beta-D-glucosyltransferase activity|UDP-D-glucose:polyribitol phosphate glucosyl transferase activity|UDP-glucose:poly(ribitol-phosphate) beta-D-glucosyltransferase activity|UDP-D-glucose polyribitol phosphate glucosyl transferase activity Catalysis of the reaction: poly(ribitol phosphate) + UDP-D-glucose = beta-D-glucosylpoly(ribitol phosphate) + UDP. CL:0002553 fibroblast of lung biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002553 A fibroblast that is part of lung. CL:0002555 fibroblast of mammary gland biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002555 A fibroblast that is part of the mammary gland. CL:0002554 fibroblast of lymphatic vessel biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002554 A fibroblast of the lymphatic system. GO:0072209 metanephric mesangial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072209 The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the metanephros as it progresses from its formation to the mature state. CL:0002557 fibroblast of pulmonary artery biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002557 A fibroblast of pulmonary artery. GO:0072208 metanephric smooth muscle tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072208 The process whose specific outcome is the progression of smooth muscle in the metanephros over time, from its formation to the mature structure. GO:0072207 metanephric epithelium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072207 The process whose specific outcome is the progression of an epithelium in the metanephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. GO:0072206 metanephric juxtaglomerular apparatus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072206 The process whose specific outcome is the progression of the juxtaglomerular apparatus in the metanephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate. GO:0072205 metanephric collecting duct development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072205 The process whose specific outcome is the progression of a collecting duct in the metanephros over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder. GO:0072204 cell-cell signaling involved in metanephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072204 cell-cell signalling involved in metanephros development Any process that mediates the transfer of information from one cell to another and contributes to the progression of the metanephros over time, from its formation to the mature organ. GO:0072203 cell proliferation involved in metanephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072203 The multiplication or reproduction of cells, resulting in the expansion of the population in the metanephros. GO:0072202 cell differentiation involved in metanephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072202 The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephros as it progresses from its formation to the mature state. GO:0072201 negative regulation of mesenchymal cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072201 Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. GO:0072200 negative regulation of mesenchymal cell proliferation involved in ureter development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072200 negative regulation of ureteral mesenchymal cell proliferation|negative regulation of ureter mesenchymal cell proliferation Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. GO:0072232 metanephric proximal convoluted tubule segment 2 development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072232 metanephric S2 development The process whose specific outcome is the progression of the S2 portion of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The S2 portion of the metanephric proximal tubule is involved in reabsorption of water and sodium chloride. GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047276 MetaCyc:2.4.1.151-RXN|EC:2.4.1.87|RHEA:13013 UDP-Gal:Galbeta1->4GlcNAc-R alpha1->3-galactosyltransferase activity|beta-D-galactosyl-N-acetylglucosaminylglycopeptide alpha-1,3-galactosyltransferase activity|UDP-Gal:Gal-beta-1->4GlcNAc-R alpha-1->3-galactosyltransferase activity|uridine diphosphogalactose-acetyllactosamine galactosyltransferase activity|UDP-Gal:beta-D-Gal(1,4)-D-GlcNAc alpha(1,3)-galactosyltransferase activity|uridine diphosphogalactose-acetyllactosamine alpha1->3-galactosyltransferase activity|beta-galactosyl-N-acetylglucosaminylglycopeptide alpha-1,3-galactosyltransferase activity|N-acetyllactosaminide alpha-1,3-galactosyltransferase activity|glucosaminylglycopeptide alpha-1,3-galactosyltransferase activity|UDPgalactose:beta-D-galactosyl-beta-1,4-N-acetyl-D-glucosaminyl-glycopeptide alpha-1,3-D-galactosyltransferase activity|UDP-Gal:N-acetyllactosaminide alpha-1,3-D-galactosyltransferase activity|UDP-Gal:beta-D-Gal(1,4)-D-GlcNAc alpha-(1,3)-galactosyltransferase activity|uridine diphosphogalactose-galactosylacetylglucosaminylgalactosyl-glucosylceramide galactosyltransferase activity|uridine diphosphogalactose-galactosylacetylglucosaminylgalactosylglucosylceramide galactosyltransferase activity|alpha-galactosyltransferase activity|UDP-Gal:N-acetyllactosaminide alpha-(1,3)-galactosyltransferase activity|UDP-galactose:N-acetyllactosaminide 3-alpha-D-galactosyltransferase activity|UDP-galactose-acetyllactosamine alpha-D-galactosyltransferase activity|UDP-Gal:N-acetyllactosaminide alpha(1,3)-galactosyltransferase activity|uridine diphosphogalactose-acetyllactosamine alpha-1->3-galactosyltransferase activity Catalysis of the reaction: beta-D-galactosyl-(1,4)-beta-N-acetyl-D-glucosaminyl-R + UDP-galactose = alpha-D-galactosyl-(1,3)-beta-D-galactosyl-(1,4)-beta-N-acetyl-D-glucosaminyl-R + UDP. GO:0106210 culmorin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106210 culmorin anabolism|culmorin biosynthesis|culmorin synthesis|culmorin formation The chemical reactions and pathways resulting in the formation of culmorin, a sesquiterpenoid fungal metabolite and mycotoxin produced by some ascomycete species such as Fusarium culmorum, F. graminearum, F. venenatum and Leptosphaeria oraemaris. GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047275 MetaCyc:2.4.1.86-RXN|EC:2.4.1.86|RHEA:16045 UDPgalactose:N-acetyl-D-glucosaminyl-1,3-D-galactosyl-1,4-D-glucosylceramide beta-D-galactosyltransferase activity|uridine diphosphogalactose-acetyl-glucosaminylgalactosylglucosylceramide galactosyltransferase activity|UDP-galactose:N-acetyl-D-glucosaminyl-1,3-D-galactosyl-1,4-D-glucosylceramide beta-D-galactosyltransferase activity|GalT-4|paragloboside synthase activity Catalysis of the reaction: N-acetyl-D-glucosaminyl-(1,3)-D-galactosyl-(1,4)-D-glucosylceramide + UDP-galactose = D-galactosyl-N-acetyl-D-glucosaminyl-(1,3)-D-galactosyl-(1,4)-D-glucosylceramide + UDP. GO:0072231 metanephric proximal convoluted tubule segment 1 development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072231 metanephric S1 development The process whose specific outcome is the progression of the S1 portion of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the metanephric proximal convoluted tubule and is responsible for avid reabsorption of water and solutes. GO:0072230 metanephric proximal straight tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072230 metanephric S3 development The process whose specific outcome is the progression of the metanephric proximal straight tubule over time, from its formation to the mature structure. The metanephric proximal straight tubule is the part of the metanephric descending limb that extends from the metanephric proximal convoluted tubule to the metanephric descending thin tubule. GO:0047274 galactinol-sucrose galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047274 MetaCyc:2.4.1.82-RXN|EC:2.4.1.82|RHEA:20161 alpha-D-galactosyl-(1->3)-myo-inositol:sucrose 6-alpha-D-galactosyltransferase activity|1-alpha-D-galactosyl-myo-inositol:sucrose 6-alpha-D-galactosyltransferase activity|galactinol:sucrose 6-galactosyl transferase activity|galactosyltransferase, galactinol-sucrose|raffinose synthase activity Catalysis of the reaction: sucrose + 1-alpha-D-galactosyl-myo-inositol = raffinose + myo-inositol. GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047273 MetaCyc:2.4.1.79-RXN|EC:2.4.1.79|Reactome:R-HSA-8878914|RHEA:22252 globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase activity|globoside synthase activity|galactosylgalactosylglucosylceramide beta-D- activity|UDP-N-acetylgalactosamine:globotriaosylceramide beta-3-N-acetylgalactosaminyltransferase activity|UDP-N-acetylgalactosamine:globotriaosylceramide beta1,3-N-acetylgalactosaminyltransferase activity|globotriosylceramide beta-1,6-N-acetylgalactosaminyltransferase activity|UDP-N-acetyl-D-galactosamine:alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide 3III-beta-N-acetyl-D-galactosaminyltransferase activity|beta-3GalNAc-T1 activity|globoside synthetase activity|UDP-N-acetyl-D-galactosamine:D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide beta-N-acetyl-D-galactosaminyltransferase activity|uridine diphosphoacetylgalactosamine-galactosylgalactosylglucosylceramide acetylgalactosaminyltransferase activity|beta3GalNAc-T1 Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide = UDP + beta-N-acetyl-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide. GO:0047272 phosphopolyprenol glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047272 MetaCyc:2.4.1.78-RXN|EC:2.4.1.78 uridine diphosphoglucose-polyprenol monophosphate glucosyltransferase activity|UDP-glucose:phosphopolyprenol D-glucosyltransferase activity|UDPglucose:phosphopolyprenol D-glucosyltransferase activity|UDPglucose:polyprenol monophosphate glucosyltransferase activity Catalysis of the reaction: polyprenyl phosphate + UDP-D-glucose = polyprenylphosphate-glucose + UDP. GO:0106214 regulation of vesicle fusion with Golgi apparatus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106214 Any process that modulates the frequency, rate or extent of vesicle fusion with Golgi apparatus. GO:1900019 regulation of protein kinase C activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900019 regulation of PKC|regulation of PKC activity Any process that modulates the frequency, rate or extent of protein kinase C activity. GO:1900018 phosphorylation of RNA polymerase II C-terminal domain serine 5 residues involved in recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900018 Any phosphorylation of RNA polymerase II C-terminal domain serine 5 residues that is involved in recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex. GO:0106213 kinetochore disassembly involved in meiotic chromosome organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106213 kinetochore disassembly from spindle pole body involved in chromosome organization involved in meiotic cell cycle The cell cycle process in which outer kinetochore components delocalize from the centromere, contributing to the rearrangement of chromosomes into the orientation characteristic of meiotic prophase I. GO:0047271 glycosaminoglycan galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047271 MetaCyc:2.4.1.74-RXN|EC:2.4.1.74 UDPgalactose:glycosaminoglycan D-galactosyltransferase activity|uridine diphosphogalactose-mucopolysaccharide galactosyltransferase activity|UDP-galactose:glycosaminoglycan D-galactosyltransferase activity Catalysis of the reaction: glycosaminoglycan + UDP-galactose = D-galactosylglycosaminoglycan + UDP. GO:0047270 lipopolysaccharide glucosyltransferase II activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047270 MetaCyc:2.4.1.73-RXN|EC:2.4.1.73 LPS glucosyltransferase II activity|UDPglucose:galactosyl-lipopolysaccharide alpha-D-glucosyltransferase activity|uridine diphosphoglucose-galactosylpolysaccharide glucosyltransferase activity|UDP-glucose:galactosyl-lipopolysaccharide alpha-D-glucosyltransferase activity Catalysis of the reaction: lipopolysaccharide + UDP-D-glucose = D-glucosyl-lipopolysaccharide + UDP. GO:0106212 centromere detachment from spindle pole body involved in meiotic chromosome organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106212 centromere detachment from SPB involved in meiotic chromosome organization|centromere detachment from spindle pole body involved in chromosome organization involved in meiotic cell cycle The cell cycle process in which centromeres dissociate from the spindle pole body, contributing to the rearrangement of chromosomes into the orientation characteristic of meiotic prophase I. GO:0106211 inositol-5-diphosphate-1,3,4,6-tetrakisphosphate diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106211 RHEA:59500 5-diphospho-myo-inositol 1,3,4,6-tetrakisphosphate diphosphatase activity|5-diphosphoinositol 1,3,4,6-tetrakisphosphate diphosphatase activity|5-PP-InsP4 activity Catalysis of the reaction: 5-diphospho-1D-myo-inositol 1,3,4,6-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + H(+) + phosphate. GO:0106218 galactosaminogalactan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106218 galactosaminogalactan biosynthesis|galactosaminogalactan anabolism|GAG biosynthetic process|galactosaminogalactan synthesis|galactosaminogalactan formation The chemical reactions and pathways resulting in the formation of the exopolysaccharide galactosaminogalactan. GAG is a heteropolysaccharide composed of alpha-1,4 linked galactose, N-acetyl galactosamine (GalNAc) and galactosamine (GalN). GO:1900015 regulation of cytokine production involved in inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900015 regulation of cytokine production involved in acute inflammatory response Any process that modulates the frequency, rate or extent of cytokine production involved in inflammatory response. CL:0002525 metanephric glomerular visceral epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002525 A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells in the metanephros. GO:1900014 obsolete cellular response to calcium ion involved in chemotaxis to cAMP biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900014 cellular response to calcium ion of chemotaxis to cAMP|cellular response to calcium ion of chemotaxis to adenosine 3',5'-cyclophosphate|cellular response to Ca2+ ion of chemotaxis to 3',5' cAMP|cellular response to calcium ion involved in chemotaxis to cAMP|cellular response to calcium ion of chemotaxis to cyclic AMP|cellular response to calcium ion of chemotaxis to 3',5' cAMP|cellular response to Ca2+ ion of chemotaxis to 3',5'-cAMP|cellular response to Ca2+ ion of chemotaxis to adenosine 3',5'-cyclophosphate|cellular response to Ca2+ ion of chemotaxis to cyclic AMP|cellular response to Ca2+ ion of chemotaxis to cAMP|cellular response to calcium ion of chemotaxis to 3',5'-cAMP OBSOLETE. The directed movement of a motile cell in response to the presence of 3',5'-cAMP that results in a change in state or activity (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus. GO:0106217 tRNA C3-cytosine methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106217 The process whereby a cytosine in a tRNA is methylated at position 3 of the cytosine. GO:1900017 positive regulation of cytokine production involved in inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900017 positive regulation of cytokine production involved in acute inflammatory response|up regulation of cytokine production involved in inflammatory response|up regulation of cytokine production involved in acute inflammatory response Any process that activates or increases the frequency, rate or extent of cytokine production involved in inflammatory response. GO:0106216 positive regulation of vesicle fusion with Golgi apparatus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106216 Any process that activates or increases the frequency, rate or extent of vesicle fusion with Golgi apparatus. GO:1900016 negative regulation of cytokine production involved in inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900016 negative regulation of cytokine production involved in acute inflammatory response|down regulation of cytokine production involved in inflammatory response|down regulation of cytokine production involved in acute inflammatory response Any process that stops, prevents or reduces the frequency, rate or extent of cytokine production involved in inflammatory response. GO:0106215 negative regulation of vesicle fusion with Golgi apparatus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106215 Any process that stops, prevents or reduces the frequency, rate or extent of vesicle fustion with Golgi apparatus. GO:1900011 negative regulation of corticotropin-releasing hormone receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900011 down regulation of adrenocorticotropin-releasing hormone receptor activity|down regulation of corticotropin-releasing factor receptor activity|negative regulation of CRH receptor activity|negative regulation of CRF receptor activity|negative regulation of adrenocorticotropin-releasing hormone receptor activity|down regulation of corticotropin-releasing hormone receptor activity|negative regulation of corticotropin-releasing factor receptor activity|down regulation of CRH receptor activity|down regulation of CRF receptor activity Any process that stops, prevents or reduces the frequency, rate or extent of corticotropin-releasing hormone receptor activity. GO:1900010 regulation of corticotropin-releasing hormone receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900010 regulation of corticotropin-releasing factor receptor activity|regulation of adrenocorticotropin-releasing hormone receptor activity|regulation of CRH receptor activity|regulation of CRF receptor activity Any process that modulates the frequency, rate or extent of corticotropin-releasing hormone receptor activity. GO:0047279 sn-glycerol-3-phosphate 1-galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047279 MetaCyc:2.4.1.96-RXN|KEGG_REACTION:R00854|EC:2.4.1.96|RHEA:20341 uridine diphosphogalactose-glycerol phosphate galactosyltransferase activity|glycerol 3-phosphate 1alpha-galactosyltransferase activity|UDP-galactose:sn-glycerol-3-phosphate 1-alpha-D-galactosyltransferase activity|UDPgalactose:sn-glycerol-3-phosphate alpha-D-galactosyltransferase activity|UDP-Gal:sn-glycero-3-phosphoric acid 1-alpha-galactosyl-transferase activity|UDPgalactose:sn-glycerol-3-phosphate 1-alpha-D-galactosyltransferase activity|isofloridoside-phosphate synthase activity Catalysis of the reaction: sn-glycerol 3-phosphate + UDP-D-galactose = 1-O-alpha-D-galactosyl-sn-glycerol 3-phosphate + H(+) + UDP. GO:0047278 bilirubin-glucuronoside glucuronosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047278 MetaCyc:2.4.1.95-RXN|RHEA:16885|KEGG_REACTION:R00062 bilirubin monoglucuronide transglucuronidase activity|bilirubin-glucuronoside:bilirubin-glucuronoside D-glucuronosyltransferase activity|bilirubin glucuronoside glucuronosyltransferase activity Catalysis of the reaction: 2 bilirubin-glucuronoside = bilirubin + bilirubin-bisglucuronoside. GO:1900013 obsolete cellular response to potassium ion involved in chemotaxis to cAMP biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900013 cellular response to potassium of chemotaxis to cAMP|cellular response to potassium ion of chemotaxis to 3',5' cAMP|cellular response to potassium of chemotaxis to 3',5' cAMP|cellular response to potassium ion involved in chemotaxis to cAMP|cellular response to K+ ion of chemotaxis to 3',5'-cAMP|cellular response to K+ ion of chemotaxis to adenosine 3',5'-cyclophosphate|cellular response to K+ ion of chemotaxis to cyclic AMP|cellular response to K+ ion of chemotaxis to cAMP|cellular response to potassium ion of chemotaxis to 3',5'-cAMP|cellular response to potassium of chemotaxis to 3',5'-cAMP|cellular response to potassium ion of chemotaxis to cAMP|cellular response to potassium ion of chemotaxis to adenosine 3',5'-cyclophosphate|cellular response to K+ ion of chemotaxis to 3',5' cAMP|cellular response to potassium of chemotaxis to adenosine 3',5'-cyclophosphate|cellular response to potassium ion of chemotaxis to cyclic AMP|cellular response to potassium of chemotaxis to cyclic AMP OBSOLETE. The directed movement of a motile cell in response to the presence of 3',5'-cAMP that results in a change in state or activity (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus. GO:0047277 globoside alpha-N-acetylgalactosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047277 MetaCyc:2.4.1.88-RXN|EC:2.4.1.88|RHEA:22164 globoside acetylgalactosaminyltransferase activity|uridine diphosphoacetylgalactosamine-globoside alpha-acetylgalactosaminyltransferase activity|UDP-N-acetyl-D-galactosamine:N-acetyl-D-galactosaminyl-1,3-D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide alpha-N-acetyl-D-galactosaminyltransferase activity|Forssman synthase activity|forssman synthase activity Catalysis of the reaction: N-acetyl-D-galactosaminyl-(1,3)-D-galactosyl-(1,4)-D-galactosyl-(1,4)-D-glucosylceramide + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-N-acetyl-D-galactosaminyl-(1,3)-D-galactosyl-(1,4)-D-galactosyl-(1,4)-D-glucosylceramide + UDP. GO:1900012 positive regulation of corticotropin-releasing hormone receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900012 up regulation of CRH receptor activity|up regulation of CRF receptor activity|positive regulation of CRH receptor activity|positive regulation of CRF receptor activity|up regulation of adrenocorticotropin-releasing hormone receptor activity|positive regulation of adrenocorticotropin-releasing hormone receptor activity|up regulation of corticotropin-releasing hormone receptor activity|positive regulation of corticotropin-releasing factor receptor activity|up regulation of corticotropin-releasing factor receptor activity Any process that activates or increases the frequency, rate or extent of corticotropin-releasing hormone receptor activity. GO:0106219 zinc ion sensor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106219 Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of zinc. GO:1900020 positive regulation of protein kinase C activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900020 positive regulation of PKC activity|up regulation of PKC activity|up regulation of PKC|positive regulation of PKC Any process that activates or increases the frequency, rate or extent of protein kinase C activity. CL:0002520 nephrocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002520 An insect excretory cell that regulates haemolymph composition by filtration and filtrate endocytosis. CL:0002522 renal filtration cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002522 A renal filtration cell is a specialized cell of the renal system that filter fluids by charge, size or both. CL:0002524 disseminated nephrocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002524 A disseminated nephrocyte is a nephrocyte that filters hemolymph and is found at scattered locations in the fat body or other tissues. CL:0002523 mesonephric glomerular visceral epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002523 A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells in the mesonephros GO:0072239 metanephric glomerulus vasculature development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072239 glomerulus capillary development The biological process whose specific outcome is the progression of a metanephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the metanephric glomerulus vasculature and ends with the mature structure. The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus. GO:0072238 metanephric long nephron development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072238 metanephric juxtamedullary nephron development The process whose specific outcome is the progression of a metanephric long nephron over time, from its formation to the mature structure. Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla in the metanephros. GO:0072237 metanephric proximal tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072237 The process whose specific outcome is the progression of the metanephric proximal tubule over time, from its formation to the mature structure. The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology. GO:0072236 metanephric loop of Henle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072236 metanephric intermediate tubule development The process whose specific outcome is the progression of the metanephric loop of Henle over time, from its formation to the mature structure. The metanephric loop of Henle is a metanephric nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule in the metanephros. GO:0072235 metanephric distal tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072235 The process whose specific outcome is the progression of the metanephric distal tubule over time, from its formation to the mature structure. The metanephric distal tubule is a metanephric nephron tubule that begins at the metanephric macula densa and extends to the metanephric connecting tubule. GO:0072234 metanephric nephron tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072234 The progression of a metanephric nephron tubule over time, from its initial formation to the mature structure. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros. GO:0072233 metanephric thick ascending limb development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072233 metanephric TAL development The process whose specific outcome is the progression of the metanephric thick ascending limb over time, from its formation to the mature structure. The metanephric thick ascending limb is the last part of the metanephric loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. At the macula densa, the thick ascending limb connects to the distal convoluted tubule. GO:0072221 metanephric distal convoluted tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072221 The process whose specific outcome is the progression of the metanephric distal convoluted tubule over time, from its formation to the mature structure. The metanephric distal convoluted tubule is the first segment of the metanephric nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter. GO:0047287 lactosylceramide alpha-2,6-N-sialyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047287 RHEA:21552|MetaCyc:2.4.99.11-RXN|EC:2.4.99.11 CMP-N-acetylneuraminate:lactosylceramide alpha-2,6-N-acetylneuraminyltransferase activity|cytidine monophosphoacetylneuraminate-lactosylceramide sialyltransferase|CMP-acetylneuraminate-lactosylceramide-sialyltransferase|CMP-sialic acid:lactosylceramide sialyltransferase activity|CMP-N-acetylneuraminic acid:lactosylceramide sialyltransferase activity Catalysis of the reaction: cytolipin-H + CMP-N-acetylneuraminate = alpha-N-acetylneuraminyl-2,6-beta-galactosyl-1,4-beta-D-glucosylceramide + CMP. GO:0047286 NAD+-diphthamide ADP-ribosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047286 EC:2.4.2.36|RHEA:11820|Reactome:R-HSA-5336421|MetaCyc:RXN-11372 NAD+:peptide-diphthamide N-(ADP-D-ribosyl)transferase activity|mono(ADP-ribosyl)transferase activity|ADP-ribosyltransferase activity|NAD-diphthamide ADP-ribosyltransferase activity Catalysis of the reaction: peptide diphthamide + NAD+ = peptide N-(ADP-D-ribosyl)diphthamide + niacinamide. GO:0072220 metanephric descending thin limb development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072220 The process whose specific outcome is the progression of the metanephric descending thin limb over time, from its formation to the mature structure. The metanephric descending thin limb is a part of the metanephric loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the metanephric loop of Henle. GO:0106220 pyocyanine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106220 pyocyanin biosynthetic process The chemical reactions and pathways resulting in the formation of pyrocyanin, an iminium betaine that is 5-methylphenazin-5-ium which is substituted at position 1 by an oxidanidyl group. GO:0047285 flavonol-3-O-glycoside xylosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047285 EC:2.4.2.35|RHEA:19701|MetaCyc:2.4.2.35-RXN UDP-D-xylose:flavonol-3-O-glycoside 2''-O-beta-D-xylosyltransferase activity Catalysis of the reaction: flavonol 3-O-glycoside + UDP-D-xylose = flavonol 3-O-D-xylosylglycoside + UDP. GO:0047284 dolichyl-xylosyl-phosphate-protein xylosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047284 EC:2.4.2.33|MetaCyc:2.4.2.33-RXN|RHEA:18361 dolichyl-D-xylosyl-phosphate:protein D-xylosyltransferase activity Catalysis of the reaction: dolichyl D-xylosyl phosphate + protein = dolichol-phosphate + D-xylosylprotein. GO:0047283 dolichyl-phosphate D-xylosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047283 EC:2.4.2.32|RHEA:15361|MetaCyc:2.4.2.32-RXN UDP-D-xylose:dolichyl-phosphate D-xylosyltransferase activity Catalysis of the reaction: dolichol-phosphate + UDP-D-xylose = dolichyl D-xylosyl phosphate + UDP. GO:0106225 peptidyl-lysine 2-hydroxyisobutyrylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106225 The 2-hydroxyisobutyrylation of a lysine residue in a protein. GO:0047282 dTDP-dihydrostreptose-streptidine-6-phosphate dihydrostreptosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047282 KEGG_REACTION:R04222|MetaCyc:2.4.2.27-RXN|RHEA:24392|EC:2.4.2.27 dTDPdihydrostreptose-streptidine-6-phosphate dihydrostreptosyltransferase activity|dTDP-L-dihydrostreptose:streptidine-6-phosphate dihydrostreptosyltransferase activity|thymidine diphosphodihydrostreptose-streptidine 6-phosphate dihydrostreptosyltransferase activity Catalysis of the reaction: dTDP-L-dihydrostreptose + streptidine 6-phosphate = O-(1->4)-alpha-L-dihydrostreptosyl-streptidine 6-phosphate + dTDP + H(+). GO:1900029 positive regulation of ruffle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900029 up regulation of membrane ruffle formation|positive regulation of membrane ruffle formation|up regulation of membrane ruffling|up regulation of ruffle assembly|positive regulation of membrane ruffling Any process that activates or increases the frequency, rate or extent of ruffle assembly. GO:0106223 germacrene A hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106223 EC:1.14.14.95|RHEA:30303 Catalysis of the reaction:(+)-(R)-germacrene A + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = germacra-1(10),4,11(13)-trien-12-oate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]. GO:0047281 dioxotetrahydropyrimidine phosphoribosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047281 EC:2.4.2.20|RHEA:10232|MetaCyc:2.4.2.20-RXN dioxotetrahydropyrimidine ribonucleotide pyrophosphorylase activity|dioxotetrahydropyrimidine-ribonucleotide pyrophosphorylase activity|dioxotetrahydropyrimidine-ribonucleotide diphosphorylase activity|dioxotetrahydropyrimidine phosphoribosyl transferase activity|2,4-dioxotetrahydropyrimidine-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase activity Catalysis of the reaction: pyrophosphate + a 2,4-dioxotetrahydropyrimidine D-ribonucleotide = PRPP + a 2,4-dioxotetrahydropyrimidine. GO:0047280 nicotinamide phosphoribosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047280 EC:2.4.2.12|RHEA:16149|KEGG_REACTION:R01271|Reactome:R-HSA-197250|MetaCyc:2.4.2.12-RXN nicotinamide-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase activity|nicotinamide mononucleotide synthetase activity|nicotinamide mononucleotide pyrophosphorylase activity|NMN pyrophosphorylase activity|NMN diphosphorylase activity|NMN synthetase activity Catalysis of the reaction: diphosphate + nicotinamide mononucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + H(+) + nicotinamide. GO:0106222 long noncoding RNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106222 lncRNA binding Interacting selectively and non-covalently with a long noncoding RNA (lncRNA). GO:1900026 positive regulation of substrate adhesion-dependent cell spreading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900026 positive regulation of substrate adhesion dependent cell spreading|up regulation of substrate adhesion-dependent cell spreading|up regulation of cell spreading during cell substrate adhesion|positive regulation of cell spreading during cell substrate adhesion|up regulation of substrate adhesion dependent cell spreading Any process that activates or increases the frequency, rate or extent of substrate adhesion-dependent cell spreading. GO:0106229 histone glutaryltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106229 Catalysis of the reaction: glutaryl-CoA + histone = CoA + H+ + N6-glutaryl-histone. GO:1900025 negative regulation of substrate adhesion-dependent cell spreading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900025 negative regulation of cell spreading during cell substrate adhesion|negative regulation of substrate adhesion dependent cell spreading|down regulation of substrate adhesion-dependent cell spreading|down regulation of cell spreading during cell substrate adhesion|down regulation of substrate adhesion dependent cell spreading Any process that stops, prevents or reduces the frequency, rate or extent of substrate adhesion-dependent cell spreading. GO:0106228 peptide glutaryltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106228 RHEA:18009 Catalysis of the reaction: glutaryl-CoA + L-lysyl-[protein] = CoA + H+ + N6-glutaryl-L-lysyl-[protein]. GO:0106227 peptidyl-lysine glutarylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106227 The glutarylation of a lysine residue in a protein. GO:1900028 negative regulation of ruffle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900028 negative regulation of membrane ruffle formation|down regulation of membrane ruffling|down regulation of ruffle assembly|down regulation of membrane ruffle formation|negative regulation of membrane ruffling Any process that stops, prevents or reduces the frequency, rate or extent of ruffle assembly. CL:0002539 aortic smooth muscle cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002539 A smooth muscle cell of the aorta. GO:1900027 regulation of ruffle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900027 regulation of membrane ruffling|regulation of membrane ruffle formation Any process that modulates the frequency, rate or extent of ruffle assembly. GO:0106226 peptide 2-hydroxyisobutyryltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106226 RHEA:24180 Catalysis of the reaction: 2-hydroxyisobutyryl-CoA + lysine in peptide = CoA + N-2-hydroxyisobutyryl-lysine-peptide. GO:1900022 regulation of D-erythro-sphingosine kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900022 regulation of sphingosine kinase activity Any process that modulates the frequency, rate or extent of D-erythro-sphingosine kinase activity. GO:0047289 galactosyldiacylglycerol alpha-2,3-sialyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047289 KEGG_REACTION:R03468|RHEA:11664|MetaCyc:2.4.99.5-RXN|EC:2.4.99.5 CMP-N-acetylneuraminate:1,2-diacyl-3-beta-D-galactosyl-sn-glycerol N-acetylneuraminyltransferase activity Catalysis of the reaction: 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + CMP-N-acetyl-beta-neuraminate = 1,2-diacyl-3-[3-(alpha-D-N-acetylneuraminyl)-beta-D-galactosyl]-sn-glycerol + CMP + H(+). GO:1900024 regulation of substrate adhesion-dependent cell spreading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900024 regulation of cell spreading during cell substrate adhesion|regulation of substrate adhesion dependent cell spreading Any process that modulates the frequency, rate or extent of substrate adhesion-dependent cell spreading. GO:1900023 positive regulation of D-erythro-sphingosine kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900023 up regulation of D-erythro-sphingosine kinase activity|up regulation of sphingosine kinase activity|positive regulation of sphingosine kinase activity Any process that activates or increases the frequency, rate or extent of D-erythro-sphingosine kinase activity. GO:0047288 monosialoganglioside sialyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047288 MetaCyc:2.4.99.2-RXN|RHEA:18021|EC:2.4.99.2 CMP-N-acetylneuraminate:D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide N-acetylneuraminyltransferase activity Catalysis of the reaction: D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + CMP-N-acetylneuraminate = N-acetylneuraminyl-D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + CMP. GO:1900031 obsolete regulation of transcription from RNA polymerase II promoter involved in calcium-mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900031 regulation of transcription from RNA polymerase II promoter of calcium signaling|regulation of gene-specific transcription from RNA polymerase II promoter of calcium ion signaling|regulation of global transcription from Pol II promoter of calcium-mediated signaling|regulation of gene-specific transcription from RNA polymerase II promoter of calcium-mediated signalling|regulation of transcription from RNA polymerase II promoter, global of calcium-mediated signaling|global transcription regulation from Pol II promoter of calcium ion signaling|global transcription regulation from Pol II promoter of calcium-mediated signalling|global transcription regulation from Pol II promoter of calcium signalling|regulation of gene-specific transcription from RNA polymerase II promoter of calcium signaling|regulation of gene-specific transcription from RNA polymerase II promoter of calcium signalling|regulation of transcription from Pol II promoter of calcium signalling|global transcription regulation from Pol II promoter of calcium signaling|regulation of transcription from RNA polymerase II promoter, global of calcium ion signaling|global transcription regulation from Pol II promoter of calcium-mediated signaling|regulation of transcription from RNA polymerase II promoter, global of calcium-mediated signalling|regulation of global transcription from Pol II promoter of calcium-mediated signalling|regulation of gene-specific transcription from RNA polymerase II promoter of calcium-mediated signaling|regulation of global transcription from Pol II promoter of calcium ion signaling|regulation of transcription from RNA polymerase II promoter of calcium signalling|regulation of transcription from Pol II promoter of calcium ion signaling|regulation of transcription from Pol II promoter of calcium-mediated signalling|regulation of transcription from RNA polymerase II promoter, global of calcium signaling|regulation of transcription from RNA polymerase II promoter of calcium-mediated signalling|regulation of transcription from RNA polymerase II promoter of calcium ion signaling|regulation of transcription from Pol II promoter of calcium-mediated signaling|regulation of global transcription from Pol II promoter of calcium signaling|regulation of global transcription from Pol II promoter of calcium signalling|regulation of transcription from RNA polymerase II promoter of calcium-mediated signaling|regulation of transcription from RNA polymerase II promoter involved in calcium-mediated signaling|regulation of transcription from RNA polymerase II promoter, global of calcium signalling|regulation of transcription from Pol II promoter of calcium signaling OBSOLETE. Any regulation of transcription from RNA polymerase II promoter that is involved in calcium-mediated signaling. GO:1900030 regulation of pectin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900030 regulation of pectin formation|regulation of pectin biosynthesis|regulation of pectin anabolism|regulation of pectin synthesis Any process that modulates the frequency, rate or extent of pectin biosynthetic process. CL:0002533 immature CD16-positive myeloid dendritic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002533 An immature CD16-positive myeloid dendritic cell is CD80-low, CD86-low, and MHCII-low. CL:0002532 CD16-positive myeloid dendritic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002532 CD16-mDC|CD16+ mDC A myeloid dendritic cell found in the blood that is CD16-positive. CL:0002535 epithelial cell of cervix biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002535 epithelial cell of neck of uterus|cervical canal of uterus epithelial cell|cervix epithelial cell|neck of uterus epithelial cell|epithelial cell of cervix of uterus|epithelial cell of cervical canal|epithelial cell of uterine cervix|cervix of uterus epithelial cell|cervical canal epithelial cell|epithelial cell of cervical canal of uterus|uterine cervix epithelial cell An epithelial cell of the cervix. CL:0002534 mature CD16-positive myeloid dendritic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002534 A mature CD16-positive myeloid dendritic cell is CD80-high, CD83-positive, CD86-high, and MHCII-high. GO:0047290 (alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047290 EC:2.4.99.7|RHEA:53896|KEGG_REACTION:R04635|MetaCyc:2.4.99.7-RXN|Reactome:R-HSA-981809 (alpha-N-acetylneuraminyl-2,3-alpha-galactosyl-1,3)-N-acetyl-galactosaminide alpha-2,6-sialyltransferase activity|(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity|alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase activity|cytidine monophosphoacetylneuraminate-(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide-alpha-2,6-sialyltransferase activity|NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2,6-sialyltransferase activity|CMP-N-acetylneuraminate:(alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3)-N-acetyl-D-galactosaminide alpha-2,6-N-acetylneuraminyl-transferase activity|ST6GALNAC activity|sialyltransferase 7D activity|sialyltransferase 3C activity|SIAT7 Catalysis of the reaction: alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-D-galactosaminyl-R + CMP-N-acetyl-beta-neuraminate = alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-D-galactosaminyl-R + CMP. GO:0072229 metanephric proximal convoluted tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072229 The process whose specific outcome is the progression of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The metanephric proximal convoluted tubule is the most proximal portion of the metanephric proximal tubule and extends from the metanephric glomerular capsule to the metanephric proximal straight tubule. CHEBI:156548 kainate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_156548 GO:0072228 metanephric prebend segment development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072228 The process whose specific outcome is the progression of the metanephric prebend segment over time, from its formation to the mature structure. The metanephric prebend segment is a part of the metanephric descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability. GO:0072227 metanephric macula densa development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072227 The process whose specific outcome is the progression of the metanephric macula densa over time, from its formation to the mature structure. The metanephric macula densa is an area of specialized cells in the distal tubule of the metanephros that makes contact with the vascular pole of the glomerulus. GO:0072226 metanephric long descending thin limb bend development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072226 The process whose specific outcome is the progression of the metanephric long descending thin limb bend over time, from its formation to the mature structure. The metanephric long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment in the metanephros. GO:0072225 metanephric late distal convoluted tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072225 The process whose specific outcome is the progression of the metanephric late distal convoluted tubule over time, from its formation to the mature structure. The metanephric late distal convoluted tubule contains metanephric DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive. GO:0072224 metanephric glomerulus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072224 metanephric glomerular development The progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or metanephros. GO:0072223 metanephric glomerular mesangium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072223 The process whose specific outcome is the progression of the metanephric glomerular mesangium over time, from its formation to the mature structure. The metanephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the metanephros, which helps to support the capillary loops in a renal glomerulus. GO:0072222 metanephric early distal convoluted tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072222 The process whose specific outcome is the progression of the metanephric early distal convoluted tubule over time, from its formation to the mature structure. The metanephric early distal convoluted tubule contains metanephric DCT cells and is vasopressin-insensitive. GO:0047298 (S)-3-amino-2-methylpropionate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047298 MetaCyc:2.6.1.22-RXN|EC:2.6.1.22|RHEA:13993|KEGG_REACTION:R04188 L-3-aminoisobutyrate aminotransferase activity|beta-aminoisobutyrate-alpha-ketoglutarate transaminase activity|L-3-aminoisobutyric aminotransferase activity|L-3-aminoisobutyrate transaminase activity|(S)-3-amino-2-methylpropanoate:2-oxoglutarate aminotransferase activity|beta-aminobutyric transaminase activity|(S)-3-amino-2-methylpropionate aminotransferase activity|L-AIBAT activity Catalysis of the reaction: (S)-3-amino-2-methylpropanoate + 2-oxoglutarate = 2-methyl-3-oxopropanoate + L-glutamate. GO:0072254 metanephric glomerular mesangial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072254 The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the metanephros as it progresses from its formation to the mature state. UBERON:0036291 myocardium of anterior wall of right ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036291 GO:0072253 metanephric juxtaglomerulus cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072253 The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric juxtaglomerulus cell. GO:0047297 asparagine-oxo-acid transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047297 EC:2.6.1.14|RHEA:19813|MetaCyc:2.6.1.14-RXN asparagine--oxo-acid aminotransferase activity|L-asparagine:2-oxo-acid aminotransferase activity|asparagine-oxo-acid aminotransferase activity|asparagine-keto acid aminotransferase activity Catalysis of the reaction: a 2-oxo acid + L-asparagine = an amino acid + 2-oxosuccinamate. UBERON:0036290 myocardium of anterior wall of left ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036290 GO:0047296 homospermidine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047296 MetaCyc:2.5.1.44-RXN|EC:2.5.1.44|RHEA:18645 putrescine:putrescine 4-aminobutyltransferase (ammonia-forming) Catalysis of the reaction: 2 putrescine = NH3 + sym-homospermidine. GO:0072252 metanephric juxtaglomerulus cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072252 The process whose specific outcome is the progression of a metanephric juxtaglomerulus cell over time, from its formation to the mature structure. GO:0047295 geranylgeranylglycerol-phosphate geranylgeranyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047295 MetaCyc:2.5.1.42-RXN|EC:2.5.1.42|RHEA:18109|KEGG_REACTION:R04520 geranylgeranyloxyglycerol phosphate geranylgeranyltransferase activity|geranylgeranyltransferase II|geranylgeranyl diphosphate:sn-3-O-(geranylgeranyl)glycerol 1-phosphate geranylgeranyltransferase activity Catalysis of the reaction: sn-3-O-(geranylgeranyl)glycerol 1-phosphate + all-trans-geranylgeranyl diphosphate = 2,3-di-O-(geranylgeranyl)glycerol 1-phosphate + diphosphate. GO:0072251 metanephric juxtaglomerulus cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072251 The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the metanephros as it progresses from its formation to the mature state. GO:0072250 metanephric glomerular visceral epithelial cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072250 metanephric podocyte cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular visceral epithelial cell. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros. GO:0047294 phosphoglycerol geranylgeranyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047294 MetaCyc:2.5.1.41-RXN|RHEA:23404|EC:2.5.1.41|KEGG_REACTION:R04158 geranylgeranyl-transferase activity|glycerol phosphate geranylgeranyltransferase activity|geranylgeranyl diphosphate:sn-glyceryl phosphate geranylgeranyltransferase activity Catalysis of the reaction: sn-glycerol 1-phosphate + all-trans-geranylgeranyl diphosphate = sn-3-O-(geranylgeranyl)glycerol 1-phosphate + diphosphate. UBERON:0036295 renal pelvis/ureter biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036295 renal pelvis plus ureter|renal pelvis and ureter The upper tract of the renal system. The renal pelvis is the large cavity in the middle of each kidney. Urine drains from each kidney through a long tube called the ureter, into the bladder, where it is stored until it is passed from the body through the urethra. GO:0047293 4-hydroxybenzoate nonaprenyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047293 EC:2.5.1.39|RHEA:17709|MetaCyc:2.5.1.39-RXN p-hydroxybenzoic acid-polyprenyl transferase activity|solanesyl-diphosphate:4-hydroxybenzoate nonaprenyltransferase activity|4-hydroxybenzoate transferase activity|p-hydroxybenzoate dimethylallyltransferase activity|nonaprenyl-4-hydroxybenzoate transferase activity|p-hydroxybenzoic-polyprenyl transferase activity|p-hydroxybenzoate polyprenyltransferase activity Catalysis of the reaction: p-hydroxybenzoate + solanesyl pyrophosphate = nonaprenyl-4-hydroxybenzoate + diphosphate. UBERON:0036294 mucosa of lip biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036294 labial mucosa A mucosa that is part of a lip region [Automatically generated definition]. GO:0047292 trihydroxypterocarpan dimethylallyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047292 EC:2.5.1.36|MetaCyc:2.5.1.36-RXN dimethylallyl-diphosphate:(6aS,11aS)-3,6a,9-trihydroxypterocarpan dimethyltransferase activity|dimethylallyl-diphosphate:(6aS,11aS)-3,6a,9-trihydroxypterocarpan dimethylallyltransferase activity|dimethylallylpyrophosphate:3,6a,9-trihydroxypterocarpan dimethylallyltransferase activity|dimethylallylpyrophosphate:trihydroxypterocarpan dimethylallyl transferase activity Catalysis of the reaction: (6AS,11AS)-3,6A,9-trihydroxypterocarpan + dimethylallyl-pyrophosphate = glyceollin + diphosphate. GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047291 EC:2.4.99.9|MetaCyc:2.4.99.9-RXN|RHEA:18417 ganglioside GM3 synthetase activity|CMP-acetylneuraminic acid:lactosylceramide sialyltransferase activity|GM3 synthase activity|CMP-N-acetylneuraminate:lactosylceramide alpha-2,3-N-acetylneuraminyltransferase activity|CMP-sialic acid:lactosylceramide-sialyltransferase activity|cytidine monophosphoacetylneuraminate-lactosylceramide sialyltransferase|ganglioside GM3 synthase activity|cytidine monophosphoacetylneuraminate-lactosylceramide alpha2,3- sialyltransferase activity|CMP-acetylneuraminate-lactosylceramide-sialyltransferase|SAT 1|GM3 synthetase activity Catalysis of the reaction: cytolipin-H + CMP-N-acetylneuraminate = alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide + CMP. Alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide is also known as GM3. CL:0002504 enteric smooth muscle cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002504 intestinal smooth muscle cell A smooth muscle cell of the intestine. GO:1900037 regulation of cellular response to hypoxia biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900037 regulation of cellular response to hypoxic stress|regulation of cellular response to lowered oxygen tension Any process that modulates the frequency, rate or extent of cellular response to hypoxia. GO:1900036 positive regulation of cellular response to heat biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900036 up regulation of cellular response to heat|up-regulation of cellular response to heat stress|activation of cellular response to heat|activation of cellular response to heat stress|up-regulation of cellular response to heat|positive regulation of cellular response to heat stress|up regulation of cellular response to heat stress|upregulation of cellular response to heat|upregulation of cellular response to heat stress Any process that activates or increases the frequency, rate or extent of cellular response to heat. CHEBI:132569 O-(S-[2R,4R,6R,8R]-2,4,6,8-tetramethyl-very-long-chain fatty acyl-pantetheine-4'-phosphoryl)serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132569 GO:1900039 positive regulation of cellular response to hypoxia biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900039 positive regulation of cellular response to hypoxic stress|positive regulation of cellular response to lowered oxygen tension|activation of cellular response to lowered oxygen tension|activation of cellular response to hypoxic stress|upregulation of cellular response to hypoxia|up-regulation of cellular response to lowered oxygen tension|up-regulation of cellular response to hypoxic stress|up-regulation of cellular response to hypoxia|upregulation of cellular response to lowered oxygen tension|upregulation of cellular response to hypoxic stress|activation of cellular response to hypoxia|up regulation of cellular response to hypoxia|up regulation of cellular response to hypoxic stress|up regulation of cellular response to lowered oxygen tension Any process that activates or increases the frequency, rate or extent of cellular response to hypoxia. GO:1900038 negative regulation of cellular response to hypoxia biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900038 downregulation of cellular response to hypoxia|negative regulation of cellular response to lowered oxygen tension|down regulation of cellular response to hypoxia|down-regulation of cellular response to lowered oxygen tension|negative regulation of cellular response to hypoxic stress|down-regulation of cellular response to hypoxic stress|inhibition of cellular response to hypoxia|inhibition of cellular response to lowered oxygen tension|inhibition of cellular response to hypoxic stress|down-regulation of cellular response to hypoxia|down regulation of cellular response to hypoxic stress|down regulation of cellular response to lowered oxygen tension|downregulation of cellular response to lowered oxygen tension|downregulation of cellular response to hypoxic stress Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to hypoxia. GO:1900033 negative regulation of trichome patterning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900033 down regulation of trichome distribution|downregulation of trichome pattern biosynthesis|downregulation of trichome spacing|inhibition of trichome pattern specification|downregulation of trichome distribution|downregulation of trichome pattern formation|inhibition of trichome patterning|down regulation of trichome spacing|down regulation of trichome pattern formation|negative regulation of trichome pattern biosynthesis|down-regulation of trichome pattern biosynthesis|down regulation of trichome patterning|negative regulation of trichome distribution|inhibition of trichome spacing|down-regulation of trichome distribution|down-regulation of trichome pattern specification|negative regulation of trichome pattern specification|inhibition of trichome pattern formation|downregulation of trichome patterning|inhibition of trichome pattern biosynthesis|downregulation of trichome pattern specification|down-regulation of trichome spacing|negative regulation of trichome spacing|down-regulation of trichome patterning|inhibition of trichome distribution|down regulation of trichome pattern specification|negative regulation of trichome pattern formation|down-regulation of trichome pattern formation|down regulation of trichome pattern biosynthesis Any process that stops, prevents or reduces the frequency, rate or extent of trichome patterning. CL:0002507 langerin-positive lymph node dendritic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002507 A dermal dendritic cell isolated from skin draining lymph nodes that is langerin-positive, MHC-II-positive, and CD4-negative and CD8a-negative. GO:1900032 regulation of trichome patterning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900032 regulation of trichome distribution|regulation of trichome spacing|regulation of trichome pattern formation|regulation of trichome pattern specification|regulation of trichome pattern biosynthesis Any process that modulates the frequency, rate or extent of trichome patterning. GO:1900035 negative regulation of cellular response to heat biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900035 downregulation of cellular response to heat|inhibition of cellular response to heat stress|down-regulation of cellular response to heat|down-regulation of cellular response to heat stress|negative regulation of cellular response to heat stress|downregulation of cellular response to heat stress|inhibition of cellular response to heat|down regulation of cellular response to heat stress|down regulation of cellular response to heat Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to heat. GO:0047299 tryptophan-phenylpyruvate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047299 EC:2.6.1.28|KEGG_REACTION:R01376|RHEA:13741|MetaCyc:2.6.1.28-RXN L-tryptophan:phenylpyruvate aminotransferase activity|tryptophan-phenylpyruvate aminotransferase activity|tryptophan--phenylpyruvate aminotransferase activity|L-tryptophan-alpha-ketoisocaproate aminotransferase activity Catalysis of the reaction: keto-phenylpyruvate + L-tryptophan = 3-(indol-3-yl)pyruvate + L-phenylalanine. GO:1900034 regulation of cellular response to heat biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900034 regulation of cellular response to heat stress Any process that modulates the frequency, rate or extent of cellular response to heat. CHEBI:132562 lysophosphatidylethanolamine O-34:4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132562 GO:1900040 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1900040 CHEBI:132561 PE(O-18:1/0:0) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132561 GO:1900042 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1900042 CHEBI:132564 phosphatidic acid 14:0 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132564 GO:1900041 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1900041 CHEBI:132565 phosphatidic acid 16:0 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132565 CHEBI:132568 phosphatidic acid 37:0 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132568 CHEBI:132567 phosphatidic acid 18:0 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132567 CHEBI:156536 oligoglycosyl-(1->4)-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_156536 GO:0072259 metanephric interstitial fibroblast development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072259 metanephros interstitial cell development The process whose specific outcome is the progression of a metanephric interstitial fibroblast over time, from its formation to the mature structure. GO:0072258 metanephric interstitial fibroblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072258 metanephros interstitial cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblasts of the metanephros as it progresses from its formation to the mature state. GO:0072257 metanephric nephron tubule epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072257 The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephric nephron tubule as it progresses from its formation to the mature state. GO:0072256 metanephric glomerular mesangial cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072256 The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular mesangial cell. GO:0072255 metanephric glomerular mesangial cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072255 The process whose specific outcome is the progression of a glomerular mesangial cell in the metanephros over time, from its formation to the mature structure. GO:0072243 metanephric nephron epithelium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072243 The process whose specific outcome is the progression of the metanephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros. GO:0072242 metanephric DCT cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072242 metanephric distal convoluted tubule cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric distal convoluted tubule cell. GO:0072241 metanephric DCT cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072241 metanephric distal convoluted tubule cell development The process whose specific outcome is the progression of a metanephric distal convoluted tubule cell over time, from its formation to the mature structure. GO:0072240 metanephric DCT cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072240 metanephric distal convoluted tubule cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the distal convoluted tubule cells of the metanephros as it progresses from its formation to the mature state. GO:1900048 positive regulation of hemostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900048 up-regulation of hemostasis|activation of hemostasis|up regulation of hemostasis|upregulation of hemostasis Any process that activates or increases the frequency, rate or extent of hemostasis. GO:1900047 negative regulation of hemostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900047 down-regulation of hemostasis|downregulation of hemostasis|down regulation of hemostasis|inhibition of hemostasis Any process that stops, prevents or reduces the frequency, rate or extent of hemostasis. GO:1900049 regulation of histone exchange biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900049 regulation of histone replacement|regulation of histone chaperone|regulation of histone displacement Any process that modulates the frequency, rate or extent of histone exchange. GO:1900044 regulation of protein K63-linked ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900044 regulation of protein K63-linked polyubiquitination Any process that modulates the frequency, rate or extent of protein K63-linked ubiquitination. GO:1900043 obsolete leptin-mediated signaling pathway involved in negative regulation of appetite biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900043 leptin-mediated signaling pathway of appetite suppression|adipocytokine signaling pathway of down regulation of appetite|leptin-mediated signaling pathway of down-regulation of appetite|leptin-mediated signaling pathway of negative regulation of appetite|leptin-mediated signalling pathway of downregulation of appetite|leptin-mediated signaling pathway of inhibition of appetite|leptin-mediated signalling pathway of negative regulation of hunger|adipocytokine signaling pathway of negative regulation of hunger|leptin-mediated signaling pathway involved in negative regulation of appetite|adipocytokine signaling pathway of downregulation of appetite|leptin-mediated signalling pathway of down-regulation of appetite|leptin-mediated signalling pathway of inhibition of appetite|adipocytokine signaling pathway of appetite suppression|leptin-mediated signaling pathway of down regulation of appetite|leptin-mediated signalling pathway of appetite suppression|leptin-mediated signalling pathway of negative regulation of appetite|adipocytokine signaling pathway of down-regulation of appetite|adipocytokine signaling pathway of negative regulation of appetite|adipocytokine signaling pathway of inhibition of appetite|leptin-mediated signaling pathway of negative regulation of hunger|leptin-mediated signalling pathway of down regulation of appetite|leptin-mediated signaling pathway of downregulation of appetite OBSOLETE. Any leptin-mediated signaling pathway that is involved in negative regulation of appetite. CL:0002518 kidney epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002518 An epithelial cell of the kidney. GO:1900046 regulation of hemostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900046 Any process that modulates the frequency, rate or extent of hemostasis. GO:1900045 negative regulation of protein K63-linked ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900045 downregulation of protein K63-linked polyubiquitination|inhibition of protein K63-linked ubiquitination|down-regulation of protein K63-linked polyubiquitination|negative regulation of protein K63-linked polyubiquitination|down regulation of protein K63-linked ubiquitination|downregulation of protein K63-linked ubiquitination|inhibition of protein K63-linked polyubiquitination|down-regulation of protein K63-linked ubiquitination|down regulation of protein K63-linked polyubiquitination Any process that stops, prevents or reduces the frequency, rate or extent of protein K63-linked ubiquitination. GO:1900051 positive regulation of histone exchange biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900051 up regulation of histone chaperone|positive regulation of histone chaperone|upregulation of histone exchange|upregulation of histone replacement|activation of histone chaperone|up-regulation of histone exchange|up-regulation of histone chaperone|up regulation of histone replacement|positive regulation of histone replacement|activation of histone exchange|activation of histone replacement|upregulation of histone chaperone|up regulation of histone exchange|up-regulation of histone replacement Any process that activates or increases the frequency, rate or extent of histone exchange. GO:1900050 negative regulation of histone exchange biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900050 inhibition of histone replacement|down regulation of histone exchange|down-regulation of histone chaperone|negative regulation of histone chaperone|down regulation of histone replacement|inhibition of histone exchange|downregulation of histone replacement|inhibition of histone chaperone|down-regulation of histone exchange|down-regulation of histone replacement|negative regulation of histone replacement|down regulation of histone chaperone|downregulation of histone chaperone|downregulation of histone exchange Any process that stops, prevents or reduces the frequency, rate or extent of histone exchange. GO:1900053 negative regulation of retinoic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900053 down regulation of retinoic acid anabolic process|down-regulation of retinoic acid biosynthetic process|inhibition of retinoic acid anabolic process|downregulation of retinoic acid biosynthetic process|down regulation of retinoic acid biosynthetic process|down-regulation of retinoic acid anabolic process|negative regulation of retinoic acid anabolic process|inhibition of retinoic acid biosynthetic process|downregulation of retinoic acid anabolic process Any process that stops, prevents or reduces the frequency, rate or extent of retinoic acid biosynthetic process. GO:1900052 regulation of retinoic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900052 regulation of retinoic acid anabolic process Any process that modulates the frequency, rate or extent of retinoic acid biosynthetic process. GO:0072249 metanephric glomerular visceral epithelial cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072249 metanephric podocyte development The process whose specific outcome is the progression of a metanephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros. GO:0072248 metanephric glomerular visceral epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072248 metanephric podocyte differentiation The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular visceral epithelial cell. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros. GO:0072247 metanephric glomerular parietal epithelial cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072247 metanephric Bowman's capsule cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular parietal epithelial cell. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes. GO:0072246 metanephric glomerular parietal epithelial cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072246 metanephric Bowman's capsule development The process whose specific outcome is the progression of a metanephric glomerular parietal epithelial cell over time, from its formation to the mature structure. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. GO:0072245 metanephric glomerular parietal epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072245 The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular parietal epithelial cell. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. CHEBI:132570 O-(S-[2R,4R,6R]-2,4,6-trimethyl-very-long-chain fatty acyl-pantetheine-4'-phosphoryl)serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132570 GO:0072244 metanephric glomerular epithelium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072244 The process whose specific outcome is the progression of the metanephric glomerular epithelium over time, from its formation to the mature structure. The metanephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the metanephros. The metanephric glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros. GO:0072276 metanephric glomerulus vasculature morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072276 The process in which the anatomical structures of the metanephric glomerulus vasculature are generated and organized. The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus. GO:0072275 metanephric glomerulus morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072275 The process in which the anatomical structures of the metanephric glomerulus are generated and organized. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros. GO:0072274 metanephric glomerular basement membrane development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072274 The process whose specific outcome is the progression of the metanephric glomerular basement membrane over time, from its formation to the mature structure. The metanephric glomerular basement membrane is the basal laminal portion of the metanephric glomerulus which performs the actual filtration. GO:0072273 metanephric nephron morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072273 The process in which the anatomical structures of the metanephric nephron are generated and organized. A metanephric nephron is the functional unit of the metanephros. GO:0072272 proximal/distal pattern formation involved in metanephric nephron development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072272 proximal-distal pattern formation involved in metanephric nephron development|proximal/distal metanephric nephron patterning The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron in the metanephros. The proximal/distal axis is defined by a line that runs from the center of the kidney (proximal end) outward (distal end). GO:0072271 metanephric short descending thin limb development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072271 The process whose specific outcome is the progression of the metanephric short descending thin limb over time, from its formation to the mature structure. The metanephric short descending thin limb is the descending thin limb of a short nephron in the metanephros that has a squamous epithelial morphology. GO:0072270 metanephric short nephron development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072270 The process whose specific outcome is the progression of a short nephron in the metanephros over time, from its formation to the mature structure. Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb. GO:1900059 positive regulation of sulfate assimilation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900059 activation of sulfate assimilation|upregulation of sulphate assimilation|up-regulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor|upregulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor|up regulation of sulfate assimilation|upregulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor|up regulation of sulphate assimilation|up-regulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor|positive regulation of sulphate assimilation|upregulation of sulfate assimilation|activation of sulphate assimilation|activation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor|up regulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor|positive regulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor|positive regulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor|up-regulation of sulphate assimilation|up-regulation of sulfate assimilation|up regulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor|activation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor Any process that activates or increases the frequency, rate or extent of sulfate assimilation. GO:1900058 regulation of sulfate assimilation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900058 regulation of sulphate assimilation|regulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor|regulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor Any process that modulates the frequency, rate or extent of sulfate assimilation. GO:1900055 regulation of leaf senescence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900055 Any process that modulates the frequency, rate or extent of leaf senescence. GO:1900054 positive regulation of retinoic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900054 activation of retinoic acid biosynthetic process|upregulation of retinoic acid anabolic process|up regulation of retinoic acid biosynthetic process|up-regulation of retinoic acid anabolic process|upregulation of retinoic acid biosynthetic process|activation of retinoic acid anabolic process|positive regulation of retinoic acid anabolic process|up-regulation of retinoic acid biosynthetic process|up regulation of retinoic acid anabolic process Any process that activates or increases the frequency, rate or extent of retinoic acid biosynthetic process. GO:1900057 positive regulation of leaf senescence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900057 up regulation of leaf senescence|activation of leaf senescence|up-regulation of leaf senescence|upregulation of leaf senescence Any process that activates or increases the frequency, rate or extent of leaf senescence. GO:1900056 negative regulation of leaf senescence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900056 downregulation of leaf senescence|down-regulation of leaf senescence|inhibition of leaf senescence|down regulation of leaf senescence Any process that stops, prevents or reduces the frequency, rate or extent of leaf senescence. GO:1900062 obsolete regulation of replicative cell aging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900062 regulation of replicative cell ageing OBSOLETE. Any process that modulates the frequency, rate or extent of replicative cell aging. CHEBI:132540 fatty acid 20:5 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132540 GO:1900061 obsolete positive regulation of transcription from RNA polymerase II promoter involved in calcium-mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900061 up regulation of transcription from RNA polymerase II promoter of calcium signaling|positive regulation of transcription from RNA polymerase II promoter involved in calcium-mediated signaling|activation of transcription from RNA polymerase II promoter of calcium signalling|upregulation of transcription from RNA polymerase II promoter of calcium-mediated signaling|upregulation of transcription from RNA polymerase II promoter of calcium-mediated signalling|upregulation of global transcription from RNA polymerase II promoter of calcium-mediated signaling|upregulation of transcription from RNA polymerase II promoter of calcium ion signaling|positive regulation of gene-specific transcription from RNA polymerase II promoter of calcium-mediated signaling|up-regulation of global transcription from RNA polymerase II promoter of calcium signalling|positive regulation of transcription from RNA polymerase II promoter of calcium signaling|positive regulation of gene-specific transcription from RNA polymerase II promoter of calcium ion signaling|up-regulation of global transcription from RNA polymerase II promoter of calcium signaling|positive regulation of gene-specific transcription from RNA polymerase II promoter of calcium-mediated signalling|positive regulation of transcription from RNA polymerase II promoter of calcium signalling|upregulation of global transcription from RNA polymerase II promoter of calcium ion signaling|upregulation of global transcription from RNA polymerase II promoter of calcium-mediated signalling|positive regulation of transcription from Pol II promoter of calcium ion signaling|positive regulation of transcription from Pol II promoter of calcium-mediated signalling|activation of transcription from RNA polymerase II promoter of calcium-mediated signaling|stimulation of transcription from RNA polymerase II promoter of calcium signalling|activation of global transcription from RNA polymerase II promoter of calcium signalling|upregulation of transcription from RNA polymerase II promoter of calcium signaling|up-regulation of global transcription from RNA polymerase II promoter of calcium-mediated signaling|up-regulation of transcription from RNA polymerase II promoter of calcium-mediated signalling|up-regulation of transcription from RNA polymerase II promoter of calcium ion signaling|positive regulation of global transcription from Pol II promoter of calcium signalling|up regulation of transcription from RNA polymerase II promoter of calcium-mediated signaling|up-regulation of transcription from RNA polymerase II promoter of calcium signalling|activation of transcription from RNA polymerase II promoter of calcium-mediated signalling|activation of transcription from RNA polymerase II promoter of calcium ion signaling|positive regulation of transcription from RNA polymerase II promoter of calcium-mediated signaling|positive regulation of gene-specific transcription from RNA polymerase II promoter of calcium signaling|stimulation of transcription from RNA polymerase II promoter of calcium ion signaling|stimulation of transcription from RNA polymerase II promoter of calcium-mediated signalling|upregulation of global transcription from RNA polymerase II promoter of calcium signaling|stimulation of global transcription from RNA polymerase II promoter of calcium-mediated signaling|positive regulation of transcription from Pol II promoter of calcium signalling|positive regulation of transcription from Pol II promoter of calcium signaling|up regulation of global transcription from RNA polymerase II promoter of calcium signalling|stimulation of global transcription from RNA polymerase II promoter of calcium ion signaling|stimulation of global transcription from RNA polymerase II promoter of calcium-mediated signalling|up regulation of global transcription from RNA polymerase II promoter of calcium-mediated signalling|up regulation of global transcription from RNA polymerase II promoter of calcium ion signaling|activation of global transcription from RNA polymerase II promoter of calcium-mediated signaling|positive regulation of global transcription from Pol II promoter of calcium-mediated signaling|up-regulation of transcription from RNA polymerase II promoter of calcium signaling|activation of transcription from RNA polymerase II promoter of calcium signaling|upregulation of transcription from RNA polymerase II promoter of calcium signalling|stimulation of transcription from RNA polymerase II promoter of calcium-mediated signaling|positive regulation of global transcription from Pol II promoter of calcium ion signaling|positive regulation of global transcription from Pol II promoter of calcium-mediated signalling|stimulation of transcription from RNA polymerase II promoter of calcium signaling|activation of global transcription from RNA polymerase II promoter of calcium ion signaling|activation of global transcription from RNA polymerase II promoter of calcium-mediated signalling|up regulation of transcription from RNA polymerase II promoter of calcium ion signaling|up regulation of transcription from RNA polymerase II promoter of calcium-mediated signalling|up regulation of global transcription from RNA polymerase II promoter of calcium-mediated signaling|up regulation of global transcription from RNA polymerase II promoter of calcium signaling|up-regulation of transcription from RNA polymerase II promoter of calcium-mediated signaling|stimulation of global transcription from RNA polymerase II promoter of calcium signaling|upregulation of global transcription from RNA polymerase II promoter of calcium signalling|positive regulation of gene-specific transcription from RNA polymerase II promoter of calcium signalling|positive regulation of transcription from RNA polymerase II promoter of calcium ion signaling|positive regulation of transcription from RNA polymerase II promoter of calcium-mediated signalling|positive regulation of transcription from Pol II promoter of calcium-mediated signaling|stimulation of global transcription from RNA polymerase II promoter of calcium signalling|up-regulation of global transcription from RNA polymerase II promoter of calcium ion signaling|up-regulation of global transcription from RNA polymerase II promoter of calcium-mediated signalling|positive regulation of global transcription from Pol II promoter of calcium signaling|up regulation of transcription from RNA polymerase II promoter of calcium signalling|activation of global transcription from RNA polymerase II promoter of calcium signaling OBSOLETE. Any positive regulation of transcription from RNA polymerase II promoter that is involved in calcium-mediated signaling. GO:1900064 positive regulation of peroxisome organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900064 up regulation of peroxisome-assembly ATPase activity|positive regulation of peroxisome-assembly ATPase activity|upregulation of peroxisome organization and biogenesis|upregulation of peroxisome organisation|up-regulation of peroxisome organization|activation of peroxisome-assembly ATPase activity|up-regulation of peroxisome organization and biogenesis|up-regulation of peroxisome-assembly ATPase activity|up regulation of peroxisome organisation|activation of peroxisome organisation|upregulation of peroxisome organization|positive regulation of peroxisome organisation|activation of peroxisome organization and biogenesis|upregulation of peroxisome-assembly ATPase activity|activation of peroxisome organization|positive regulation of peroxisome organization and biogenesis|up regulation of peroxisome organization and biogenesis|up regulation of peroxisome organization|up-regulation of peroxisome organisation Any process that activates or increases the frequency, rate or extent of peroxisome organization. GO:1900063 regulation of peroxisome organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900063 regulation of peroxisome organization and biogenesis|regulation of peroxisome organisation|regulation of peroxisome-assembly ATPase activity Any process that modulates the frequency, rate or extent of peroxisome organization. CHEBI:132541 fatty acid 22:1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132541 CHEBI:132544 fatty acid 22:6 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132544 CHEBI:50390 EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50390 CHEBI:132543 fatty acid 22:5 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132543 GO:1900060 negative regulation of ceramide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900060 down-regulation of ceramide biosynthetic process|downregulation of ceramide anabolism|down regulation of ceramide anabolism|downregulation of ceramide synthesis|inhibition of ceramide biosynthesis|downregulation of ceramide formation|down regulation of ceramide synthesis|down regulation of ceramide formation|inhibition of ceramide anabolism|inhibition of ceramide biosynthetic process|down regulation of ceramide biosynthesis|inhibition of ceramide synthesis|inhibition of ceramide formation|downregulation of ceramide biosynthesis|down regulation of ceramide biosynthetic process|negative regulation of ceramide anabolism|downregulation of ceramide biosynthetic process|down-regulation of ceramide anabolism|negative regulation of ceramide synthesis|down-regulation of ceramide synthesis|down-regulation of ceramide biosynthesis|negative regulation of ceramide biosynthesis|negative regulation of ceramide formation|down-regulation of ceramide formation Any process that stops, prevents or reduces the frequency, rate or extent of a ceramide biosynthetic process. CHEBI:50398 succinamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50398 GO:0072279 convergent extension involved in metanephric nephron morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072279 The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron in the metanephros. GO:0072278 metanephric comma-shaped body morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072278 The process in which the metanephric comma-shaped body is generated and organized. The metanephric comma-shaped body is the precursor structure to the metanephric S-shaped body that contributes to the morphogenesis of a nephron in the metanephros. GO:0072277 metanephric glomerular capillary formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072277 The process that gives rise to a metanephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts. GO:0072265 metanephric capsule morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072265 The process in which the anatomical structures of the metanephric capsule are generated and organized. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. GO:0072264 metanephric glomerular endothelium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072264 The process whose specific outcome is the progression of the metanephric glomerular endothelium over time, from its formation to the mature structure. The metanephric glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus of the metanephros. GO:0072263 metanephric intraglomerular mesangial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072263 The multiplication or reproduction of intraglomerular glomerular mesangium cells in the metanephros by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis. CHEBI:50389 alpha-D-Glcp-(1->6)-alpha-D-Glcp-(1->6)-alpha-D-Glcp biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50389 GO:0072262 metanephric glomerular mesangial cell proliferation involved in metanephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072262 The multiplication or reproduction of glomerular mesangial cells in the metanephros, resulting in the expansion of the population. CHEBI:50388 tuberculosinyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50388 GO:0072261 metanephric extraglomerular mesangial cell proliferation involved in metanephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072261 metanephric Goormaghtigh proliferation|metanephric lacis cell proliferation The multiplication or reproduction of extraglomerular glomerular mesangium cells in the metanephros by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa. GO:0072260 metanephric interstitial fibroblast fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072260 metanephros interstitial cell fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric interstitial fibroblast. CHEBI:132559 lysophosphatidylethanolamine 20:5 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132559 GO:1900069 regulation of cellular hyperosmotic salinity response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900069 regulation of cellular response to hyperosmotic salt stress Any process that modulates the frequency, rate or extent of cellular hyperosmotic salinity response. GO:1900066 positive regulation of ethanol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900066 upregulation of ethanol degradation|upregulation of ethanol catabolism|up-regulation of ethanol catabolic process|upregulation of ethanol breakdown|activation of ethanol catabolism|up regulation of ethanol degradation|up-regulation of ethanol catabolism|activation of ethanol degradation|positive regulation of ethanol degradation|upregulation of ethanol catabolic process|up regulation of ethanol breakdown|activation of ethanol breakdown|positive regulation of ethanol breakdown|activation of ethanol catabolic process|positive regulation of ethanol catabolism|up-regulation of ethanol degradation|up regulation of ethanol catabolic process|up regulation of ethanol catabolism|up-regulation of ethanol breakdown Any process that activates or increases the frequency, rate or extent of ethanol catabolic process. GO:1900065 regulation of ethanol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900065 regulation of ethanol degradation|regulation of ethanol breakdown|regulation of ethanol catabolism Any process that modulates the frequency, rate or extent of ethanol catabolic process. GO:1900068 negative regulation of cellular response to alkaline pH biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900068 downregulation of cellular response to alkaline pH|down regulation of cellular response to alkaline pH|down-regulation of cellular response to alkalinity|inhibition of cellular response to alkaline pH|down regulation of cellular response to basic pH|inhibition of cellular response to alkalinity|downregulation of cellular response to basic pH|negative regulation of cellular response to basic pH|down-regulation of cellular response to basic pH|down-regulation of cellular response to alkaline pH|down regulation of cellular response to alkalinity|inhibition of cellular response to basic pH|downregulation of cellular response to alkalinity|negative regulation of cellular response to alkalinity Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to alkalinity. GO:1900067 regulation of cellular response to alkaline pH biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900067 regulation of cellular response to basic pH|regulation of cellular response to alkalinity Any process that modulates the frequency, rate or extent of cellular response to alkalinity. GO:1900073 regulation of neuromuscular synaptic transmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900073 Any process that modulates the frequency, rate or extent of neuromuscular synaptic transmission. GO:1900072 positive regulation of sulfite transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900072 up regulation of sulfite transport|up-regulation of sulphite transport|activation of sulphite transport|up-regulation of sulfite transport|positive regulation of sulphite transport|up regulation of sulphite transport|upregulation of sulfite transport|upregulation of sulphite transport|activation of sulfite transport Any process that activates or increases the frequency, rate or extent of sulfite transport. GO:1900075 positive regulation of neuromuscular synaptic transmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900075 up regulation of neuromuscular synaptic transmission|activation of neuromuscular synaptic transmission|up-regulation of neuromuscular synaptic transmission|upregulation of neuromuscular synaptic transmission Any process that activates or increases the frequency, rate or extent of neuromuscular synaptic transmission. GO:1900074 negative regulation of neuromuscular synaptic transmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900074 down-regulation of neuromuscular synaptic transmission|inhibition of neuromuscular synaptic transmission|down regulation of neuromuscular synaptic transmission|downregulation of neuromuscular synaptic transmission Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular synaptic transmission. CHEBI:132554 oligomer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132554 GO:1900071 regulation of sulfite transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900071 regulation of sulphite transport Any process that modulates the frequency, rate or extent of sulfite transport. GO:1900070 negative regulation of cellular hyperosmotic salinity response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900070 down regulation of cellular response to hyperosmotic salt stress|down-regulation of cellular hyperosmotic salinity response|inhibition of cellular hyperosmotic salinity response|downregulation of cellular response to hyperosmotic salt stress|negative regulation of cellular response to hyperosmotic salt stress|down-regulation of cellular response to hyperosmotic salt stress|inhibition of cellular response to hyperosmotic salt stress|down regulation of cellular hyperosmotic salinity response|downregulation of cellular hyperosmotic salinity response Any process that stops, prevents or reduces the frequency, rate or extent of cellular hyperosmotic salinity response. CHEBI:50383 nicotinamide mononucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50383 CHEBI:50387 tuberculosinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50387 GO:0072269 metanephric long descending thin limb development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072269 The process whose specific outcome is the progression of the metanephric long descending thin limb over time, from its formation to the mature structure. The metanephric long descending thin limb is the descending thin limb of a long nephron in the metanephros that has a squamous epithelial morphology. The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla. GO:0072268 pattern specification involved in metanephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072268 pattern formation involved in metanephros development|metanephros pattern specification|metanephros pattern formation Any developmental process that results in the creation of defined areas or spaces within the metanephros to which cells respond and eventually are instructed to differentiate. GO:0072267 metanephric capsule specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072267 The regionalization process in which the identity of the metanephric capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized. GO:0072266 metanephric capsule formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072266 The developmental process pertaining to the initial formation of a metanephric capsule from unspecified parts. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. CHEBI:74347 FMN-L-threonine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74347 GO:0106276 biliberdin reductase NAD+ activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106276 EC:1.3.1.24|RHEA:15797 Catalysis of the reaction: bilirubin + NAD+ = biliverdin + NADH+ H+. GO:0106275 NADP+-protein-arginine ADP-ribosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106275 RHEA:54884|EC:2.4.2.31 Catalysis of the reaction: NADP+ + L-arginine = nicotinamide + N2-(ADP-D-ribosyl)-L-arginine. CHEBI:74346 FMN-L-threonine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74346 GO:0106274 NAD+-protein-arginine ADP-ribosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106274 EC:2.4.2.31|RHEA:19149 Catalysis of the reaction: NAD+ + L-arginine = nicotinamide + N2-(ADP-D-ribosyl)-L-arginine. GO:0106273 cytosol to ERGIC protein transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106273 The directed movement of proteins from the cystosol to the endoplasmic reticulum-Golgi intermediate compartment (ERGIC). UBERON:0012283 femoral fat pad biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012283 femoral fat depot encapsulated adipose tissue associated with the femur GO:0106279 negative regulation of UDP-N-acetylglucosamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106279 negative regulation of UDP-N-acetylglucosamine synthesis|negative regulation of UDP-N-acetylglucosamine formation|negative regulation of UDP-N-acetylglucosamine biosynthesis|negative regulation of UDP-GlcNAc biosynthesis|negative regulation of UDP-GlcNAc biosynthetic process|negative regulation of UDP-N-acetylglucosamine anabolism Any process that stops, prevents or reduces the frequency, rate or extent of the UDP-N-acetylglucosamine biosynthetic process. GO:0106278 regulation of UDP-N-acetylglucosamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106278 regulation of UDP-GlcNAc biosynthetic process|regulation of UDP-N-acetylglucosamine anabolism|regulation of UDP-N-acetylglucosamine biosynthesis|regulation of UDP-N-acetylglucosamine synthesis|regulation of UDP-N-acetylglucosamine formation Any process that modulates the frequency, rate or extent of the UDP-N_acetylglucosamine biosynthetic process. UBERON:0012282 mammary fat pad biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012282 encapsulated adipose tissue associated with the mammary gland UBERON:0036253 orifice of skull biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036253 skull orifice|cranial orifice GO:0106277 biliverdin reductase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106277 EC:1.3.1.24|RHEA:15793 Catalysis of the reaction: bilirubin + NADP+ = biliverdin + NADPH + H+. UBERON:0036255 interoceptive system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036255 The system that is responsible for sensing the internal state of the body. UBERON:0012287 Rathkes pouch epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012287 A epithelial sac that is part of a Rathke's pouch. CHEBI:74340 1-heptadecanoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74340 GO:0106283 ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106283 RHEA:42028 Catalysis of the reaction: NAD(+) + ursodeoxycholate = 7-oxolithocholate + H(+) + NADH. GO:0106282 isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106282 RHEA:42024 Catalysis of the reaction: 3beta,7beta-dihydroxy-5beta-cholan-24-oate + NAD(+) = 3beta-hydroxy-7-oxo-5beta-cholan-24-oate + H(+) + NADH. CHEBI:74345 1-(5-hydroxy-2-oxo-2,3-dihydroimidazol-4-yl)urea biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74345 GO:0106281 chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106281 RHEA:42036 Catalysis of the reaction: chenodeoxycholate + NAD(+) = 7-oxolithocholate + H(+) + NADH. GO:0106280 positive regulation of UDP-N-acetylglucosamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106280 positive regulation of UDP-N-acetylglucosamine anabolism|positive regulation of UDP-N-acetylglucosamine synthesis|positive egulation of UDP-N-acetylglucosamine formation|positive regulation of UDP-N-acetylglucosamine biosynthesis|positive regulation of UDP-GlcNAc biosynthetic process Any process that activates or increases the frequency, rate or extent of the UDP-N-acetylglucosamine biosynthetic process. CHEBI:74344 1-arachidonoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74344 CHEBI:74358 (11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74358 GO:0106287 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0106287 GO:0106286 (E)-caffeate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106286 RHEA:36299 Catalysis of the reaction: (E)-caffeate + ATP + CoA = (E)-caffeoyl-CoA + AMP + diphosphate. CHEBI:74359 L-alpha-aminobutyrate zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74359 UBERON:0036262 uterine ligament biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036262 Any of the eight ligaments pertaining to the uterus including the anterior, posterior, lateral, sacro-uterine and round ligaments. UBERON:0036264 zygomaticotemporal nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036264 zygomaticotemporal branch|zygomaticotemporal|zygomaticotemporal branch of zygomatic nerve|ramus zygomaticotemporalis (Nervus zygomaticus)|ramus zygomaticotemporalis nervus zygomatici The zygomaticotemporal nerve or zygomaticotemporal branch (temporal branch) is derived from the maxillary branch of the trigeminal nerve (Cranial nerve V). It runs along the lateral wall of the orbit in a groove in the zygomatic bone, receives a branch of communication from the lacrimal, and passes through zygomaticotemporal foramen in the zygomatic bone to enter the temporal fossa. It ascends between the bone, and substance of the Temporalis muscle, pierces the temporal fascia about 2.5 cm. above the zygomatic arch, and is distributed to the skin of the side of the forehead, and communicates with the facial nerve and with the auriculotemporal branch of the mandibular nerve. As it pierces the temporal fascia, it gives off a slender twig, which runs between the two layers of the fascia to the lateral angle of the orbit. GO:0106289 negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106289 Any process that stops, prevents, or reduces the frequency, rate or extent of deadenylation-dependent decapping of nuclear-transcribed mRNA. GO:0106288 regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106288 Any process that modulates the frequency, rate or extent of deadenylation-dependent decapping of nuclear-transcribed mRNA. UBERON:0012276 endometrium glandular epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012276 glandular part of endometrium|uterine glands set|uterine glands UBERON:0036268 pelvic vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036268 UBERON:0012275 meso-epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012275 mesoderm-derived epithelium|mesoepithelium Epithelium that derives from the mesoderm. [Automatically generated definition]. UBERON:0012274 columnar epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012274 An epithelium that consists of columnar epithelial cells. Columnar epithelia are epithelial cells whose heights are at least four times their width. Columnar epithelia are divided into simple (or unilayered), and the rarer stratified (or multi-layered).[WP, modified] UBERON:0036267 vulval vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036267 UBERON:0036269 penis blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036269 penis vasculature|vasculature of penis UBERON:0012278 gland of nasal mucosa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012278 nasal gland|glandula nasalis|glandulae nasales The nasal glands are the seromucous glands in the respiratory region of the nasal mucous membrane. The three major types of nasal glands are anterior serous glands, seromucous glands, and Bowman glands. GO:0106290 trans-cinnamate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106290 RHEA:64788 Catalysis of the reaction: (E)-cinnamate + ATP + CoA = (E)-cinnamoyl-CoA + AMP + diphosphate. CHEBI:74351 aclacinomycin T biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74351 GO:0106294 NADPH oxidase H202-forming activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106294 RHEA:11260 Catalysis of the reaction: NADPH + H+ + O2 = NADP + hydrogen peroxide (H2O2). CHEBI:74354 15-demethylaclacinomycin T zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74354 GO:0106293 NADH oxidase H202-forming activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106293 RHEA:11264 Catalysis of the reaction: NADH + H+ + O2 = NAD + hydrogen peroxide (H2O2). CHEBI:74353 aclacinomycin A(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74353 GO:0106292 superoxide-generating NADPH oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106292 RHEA:63180 Catalysis of the reaction: NADPH + 2 O2 = H(+) + NADP(+) + 2 superoxide. GO:0106291 superoxide-generating NADH oxidase activity. biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106291 RHEA:63184 Catalysis of the reaction: NADH + 2 O2 = H(+) + NAD(+) + 2 superoxide. CHEBI:74355 3-oxotriacontanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74355 GO:0106298 13-series resolvin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106298 The chemical reactions and pathways resulting in the formation of resolvin family 13-series, hydroxy fatty acids derived from docosapentaenoic acid. GO:0106297 E-series resolvin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106297 The chemical reactions and pathways resulting in the formation of resolvin family E-series, hydroxy fatty acids derived from icosapentaenoic acid. GO:0106296 D-series resolvin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106296 The chemical reactions and pathways resulting in the formation of resolvin family D-series, hydroxy fatty acids derived from docosahexaenoic acid. GO:0106295 resolvin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106295 The chemical reactions and pathways resulting in the formation of resolvins, di- or trihydroxy fatty acids derived from omega-3 polyunsaturated fatty acids, specifically icosapentaenoic acid, docosahexaenoic acid and docosapentaenoic acid. GO:0106299 resolution phase response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106299 An active host response phase of acute inflammation driven by specialized pro-resolving mediators (SPMs) and signaling pathways, enabling timely tissue regeneration and return of function. CHEBI:74361 5-oxo-delta-bilirubin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74361 CHEBI:74360 (13Z,16Z,19Z,22Z,25Z)-3-oxooctacosapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74360 CHEBI:74363 Ala-Asp(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74363 CHEBI:74362 15-oxo-beta-bilirubin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74362 CHEBI:74364 phosphatidylinositol 28:0(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74364 UBERON:0012251 ectocervical epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012251 exocervical epithelium A epithelium that is part of a ectocervix. UBERON:0012250 cervix glandular epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012250 cervix columnar epithelium A glandular epithelium that is part of a uterine cervix. UBERON:0036286 wall of right ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036286 pared del ventrC-culo derecho@es|right ventricular wall Wall of ventricle which is continuous with the wall of pulmonary trunk. UBERON:0036285 wall of left ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036285 pared del ventrC-culo izquierdo@es|left ventricular wall Wall of ventricle which is continuous with the wall of aorta. GO:0047207 1,2-beta-fructan 1F-fructosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047207 MetaCyc:2.4.1.100-RXN|EC:2.4.1.100 2,1-beta-D-fructan:2,1-beta-D-fructan 1-beta-D-fructosyltransferase activity|1,2-beta-D-fructan 1(F)-fructosyltransferase activity|1,2-beta-D-fructan 1F-fructosyltransferase activity|1,2-beta-fructan 1(F)-fructosyltransferase activity|2,1-fructan:2,1-fructan 1-fructosyltransferase activity|1,2-beta-D-fructan:1,2-beta-D-fructan 1F-beta-D-fructosyltransferase activity|fructan:fructan fructosyl transferase activity|1,2-beta-D-fructan:1,2-beta-D-fructan 1(F)-beta-D-fructosyltransferase activity|FFT activity Catalysis of the reaction: [(1->2)-beta-D-fructosyl](n) + [(1->2)-beta-D-fructosyl](m) = [(1->2)-beta-D-fructosyl](n+1) + [(1->2)-beta-D-fructosyl](m-1). UBERON:0036288 anterior wall of left ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036288 GO:0047206 UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047206 MetaCyc:2.3.2.10-RXN|EC:2.3.2.10|RHEA:12432 L-alanyl-tRNA:UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine 6-N-alanyltransferase activity|L-alanyl-tRNA:UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine N6-alanyltransferase activity|uridine diphosphoacetylmuramoylpentapeptide lysine N6-alanyltransferase activity|uridine diphosphoacetylmuramoylpentapeptide lysine N(6)-alanyltransferase activity|UDP-N-acetylmuramoylpentapeptide lysine N6-alanyltransferase activity|alanyl-transfer ribonucleate-uridine diphosphoacetylmuramoylpentapeptide transferase activity|UDP-N-acetylmuramoylpentapeptide lysine N(6)-alanyltransferase activity Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + L-alanyl-tRNA = UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-N6-(L-alanyl)-L-lysyl-D-alanyl-D-alanine + tRNA. UBERON:0012254 abdominal aorta artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012254 abdominal artery|artery of abdomen An artery that originates from the abdominal aorta GO:0047205 quinate O-hydroxycinnamoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047205 MetaCyc:2.3.1.99-RXN|EC:2.3.1.99|RHEA:15021 hydroxycinnamoyl coenzyme A-quinate transferase activity|feruloyl-CoA:quinate O-(hydroxycinnamoyl)transferase activity Catalysis of the reaction: feruloyl-CoA + quinate = O-feruloylquinate + CoA. UBERON:0012253 cervical squamo-columnar junction biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012253 squamocolumnar junction|squamo-columnar junction of uterine cervix|squamocolumnar junction of uterine cervix Region of cervical epithelium where columnar epithelium of endocervic and the stratified non-keratinising squamous epithelium of the ectocervic meet GO:0047204 chlorogenate-glucarate O-hydroxycinnamoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047204 MetaCyc:2.3.1.98-RXN|KEGG_REACTION:R02998|EC:2.3.1.98|RHEA:23204 chlorogenic acid:glucaric acid O-caffeoyltransferase activity|chlorogenate:glucarate O-(hydroxycinnamoyl)transferase activity|chlorogenate:glucarate caffeoyltransferase activity Catalysis of the reaction: D-glucarate + chlorogenate = (-)-quinate + 2-O-caffeoylglucarate. UBERON:0012252 endocervical epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012252 endocervical glandular epithelium The glandular epithelium that lines the endocervix. UBERON:0036289 anterior wall of right ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036289 Region of wall of right ventricle which is continuous with the lateral and septal walls of right ventricle. GO:0047203 13-hydroxylupinine O-tigloyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047203 MetaCyc:2.3.1.93-RXN|KEGG_REACTION:R04205|EC:2.3.1.93|RHEA:12360 (E)-2-methylcrotonoyl-CoA:13-hydroxylupinine O-2-methylcrotonoyltransferase activity|tigloyl-CoA:13-hydroxylupanine O-tigloyltransferase activity|13-hydroxylupanine acyltransferase activity Catalysis of the reaction: 13-hydroxylupanine + 2-methylcrotonoyl-CoA = 13-(2-methylcrotonoyloxy)lupanine + CoA. GO:0047202 sinapoylglucose-choline O-sinapoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047202 MetaCyc:2.3.1.91-RXN|RHEA:12024|EC:2.3.1.91|KEGG_REACTION:R03075 1-O-(4-hydroxy-3,5-dimethoxycinnamoyl)-beta-D-glucose:choline 1-O-(4-hydroxy-3,5-dimethoxycinnamoyl)transferase activity|sinapine synthase activity Catalysis of the reaction: 1-O-sinapoyl-beta-D-glucose + choline = O-sinapoylcholine + D-glucose. GO:0047201 beta-glucogallin O-galloyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047201 MetaCyc:2.3.1.90-RXN|RHEA:11416|KEGG_REACTION:R00049|EC:2.3.1.90 1-O-galloyl-beta-D-glucose:1-O-galloyl-beta-D-glucose O-galloyltransferase activity Catalysis of the reaction: 2 1-O-galloyl-beta-D-glucose = 1,6-bis-O-galloyl-beta-D-glucose + D-glucose. GO:0047200 tetrahydrodipicolinate N-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047200 EC:2.3.1.89|KEGG_REACTION:R04364|RHEA:13085|MetaCyc:2.3.1.89-RXN acetyl-CoA:(S)-2,3,4,5-tetrahydrodipicolinate-2,6-dicarboxylate N2-acetyltransferase activity|tetrahydrodipicolinate acetylase activity|acetyl-CoA:L-2,3,4,5-tetrahydrodipicolinate N2-acetyltransferase activity|tetrahydrodipicolinate:acetyl-CoA acetyltransferase activity|acetyl-CoA:(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate 2-N-acetyltransferase activity Catalysis of the reaction: (S)-2,3,4,5-tetrahydrodipicolinate + acetyl-CoA + H(2)O = L-2-acetamido-6-oxopimelate + CoA. UBERON:0012249 ectocervix biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012249 ectocervix|portio vaginalis cervicis|exocervix|vaginal part of cervix|portio vaginalis|uterine ectocervix The part of the cervix uteri that protrudes into the vagina and is lined with stratified squamous epithelium. GO:0047209 coniferyl-alcohol glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047209 EC:2.4.1.111|RHEA:23944|MetaCyc:2.4.1.111-RXN UDP-glucose:coniferyl-alcohol 4'-beta-D-glucosyltransferase activity|UDPglucose:coniferyl-alcohol 4'-beta-D-glucosyltransferase activity|UDP-glucose coniferyl alcohol glucosyltransferase activity|uridine diphosphoglucose-coniferyl alcohol glucosyltransferase activity Catalysis of the reaction: coniferyl alcohol + UDP-D-glucose = coniferin + UDP. GO:0047208 o-dihydroxycoumarin 7-O-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047208 KEGG_REACTION:R03548|RHEA:14325|MetaCyc:2.4.1.104-RXN|EC:2.4.1.104 uridine diphosphoglucose-o-dihydroxycoumarin 7-O-glucosyltransferase activity|UDPglucose:7,8-dihydroxycoumarin 7-O-beta-D-glucosyltransferase activity|UDP-glucose:7,8-dihydroxycoumarin 7-O-beta-D-glucosyltransferase activity|UDP-glucose:o-dihydroxycoumarin glucosyltransferase activity Catalysis of the reaction: 7,8-dihydroxycoumarin + UDP-D-glucose = daphnin + H(+) + UDP. CL:1000182 malpighian tubule tip cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000182 GO:0106232 hydroxyisourate hydrolase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0106232 HIU hydrolase complex|5-hydroxyisourate hydrolase complex|HIUH complex A hydrolase complex that converts 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline. This is the second step of the three-step enzymatic reaction that degrades uric acid to (S)-allantoin. GO:0047210 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0047210 GO:0106231 protein-propionyllysine depropionylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106231 RHEA:23500 Catalysis of the reaction:H2O + N(6)-propanoyl-L-lysyl-[protein] + NAD(+) = 3''-O-propanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide. GO:0106230 protein depropionylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106230 The removal of a propionyl group from a residue in a peptide or protein. GO:0106236 rhamnolipid biosynthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106236 rhamnolipid production The chemical reactions and pathways resulting in the formation/production of a glycolipid surfactant that acts as a bacterial biofilm dispersal. GO:0106235 ceramide-1-phosphate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106235 RHEA:50888 Catalysis of the reaction: ceramide-1-phosphate + H2O = ceramide+ phosphate. GO:0106234 outer membrane protein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0106234 Any protein complex that is part of the bacterial outer membrane. An example In E.coli, is RcsF associated with any one of several outer membrane beta-barrel proteins (OMPs), such as OmpA, OmpF, or OmpcC. GO:0106233 glycosome organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106233 glycosome organization and biogenesis|glycosome biogenesis|glycosome organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a glycosome, a membrane-bounded organelle found in organisms from the order Kinetoplastida that houses the enzymes of glycolysis. GO:0047218 hydroxycinnamate 4-beta-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047218 MetaCyc:2.4.1.126-RXN|EC:2.4.1.126|RHEA:21636 uridine diphosphoglucose-hydroxycinnamate glucosyltransferase activity|UDP-glucose:trans-4-hydroxycinnamate 4-O-beta-D-glucosyltransferase activity|UDPglucose:trans-4-hydroxycinnamate 4-O-beta-D-glucosyltransferase activity|UDP-glucose-hydroxycinnamate glucosyltransferase activity|hydroxycinnamoyl glucosyltransferase activity Catalysis of the reaction: 4-coumarate + UDP-D-glucose = 4-O-beta-D-glucosyl-4-hydroxycinnamate + UDP. GO:0106239 9,13-epoxylabda-14-ene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106239 EC:4.2.3.189|RHEA:54512 Catalysis of the reaction:peregrinol diphosphate = (13R)-9,13-epoxylabd-14-ene + diphosphate. GO:0047217 sucrose-1,6-alpha-glucan 3(6)-alpha-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047217 MetaCyc:2.4.1.125-RXN|EC:2.4.1.125 water-soluble-glucan synthase activity|sucrose:1,6-alpha-D-glucan 3(6)-alpha-D-glucosyltransferase activity|GTF-S|sucrose:1,6-, 1,3-alpha-D-glucan 3-alpha- and 6-alpha-D-glucosyltransferase|sucrose:1,6-alpha-D-glucan 3-alpha- and 6-alpha-glucosyltransferase activity Catalysis of the reaction: sucrose + 1,6-alpha-D-glucosyl(n) = 1,6-alpha-D-glucosyl(n+1) + fructose. GO:0106238 peregrinol diphosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106238 EC:4.2.1.174|RHEA:54652 Catalysis of the reaction:peregrinol diphosphate = all-trans-geranylgeranyl diphosphate + H2O. GO:0047216 inositol 3-alpha-galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047216 RHEA:12464|MetaCyc:2.4.1.123-RXN|EC:2.4.1.123 uridine diphosphogalactose-inositol galactosyltransferase activity|UDP-D-galactose:inositol galactosyltransferase activity|UDPgalactose:myo-inositol 1-alpha-D-galactosyltransferase activity|galactinol synthase activity|UDP-galactose:myo-inositol 1-alpha-D-galactosyltransferase activity|UDP-galactose:myo-inositol 3-alpha-D-galactosyltransferase activity|inositol 1-alpha-galactosyltransferase activity Catalysis of the reaction: myo-inositol + UDP-galactose = O-alpha-D-galactosyl-(1,3)-1D-myo-inositol + UDP. GO:0047215 indole-3-acetate beta-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047215 RHEA:14921|MetaCyc:2.4.1.121-RXN|KEGG_REACTION:R03094|EC:2.4.1.121 indol-3-ylacetylglucose synthase activity|IAA-glucose synthase activity|UDP-glucose:(indol-3-yl)acetate beta-D-glucosyltransferase activity|uridine diphosphoglucose-indoleacetate glucosyltransferase activity|UDP-glucose:indol-3-acetic acid glucosyltransferase activity|UDP-glucose:indol-3-ylacetate glucosyl-transferase activity|IAA-Glu synthetase activity|IAGlu synthase activity|UDP-glucose:auxin glucosyltransferase activity|UDPglucose:indole-3-acetate beta-D-glucosyltransferase activity|UDPG-indol-3-ylacetyl glucosyl transferase activity|UDP-glucose:indol-3-ylacetate glucosyltransferase activity Catalysis of the reaction: (indol-3-yl)acetate + UDP-D-glucose = 1-O-(indol-3-ylacetyl)-beta-D-glucose + UDP. GO:0106237 arachidonate 12(R)-lipoxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106237 Catalysis of the reaction: arachidonate + O(2)=(5Z,8Z,10E,12R,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoate. GO:0047214 cyanidin-3-rhamnosylglucoside 5-O-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047214 MetaCyc:2.4.1.116-RXN|RHEA:12144|EC:2.4.1.116 uridine diphosphoglucose-cyanidin 3-rhamnosylglucoside 5-O-glucosyltransferase activity|UDP-glucose:cyanidin-3-O-D-rhamnosyl-1,6-D-glucoside 5-O-D-glucosyltransferase activity|cyanidin-3-O-rutinoside 5-O-glucosyltransferase activity|UDP-glucose:cyanidin-3-O-beta-L-rhamnosyl-(1->6)-beta-D-glucoside 5-O-beta-D-glucosyltransferase activity Catalysis of the reaction: cyanidin-3-O-D-rhamnosyl-(1,6)-D-glucoside + UDP-D-glucose = cyanidin-3-O-[D-rhamnosyl-(1,6)-D-glucoside]-5-O-D-glucoside + UDP. UBERON:0036215 anatomical surface region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036215 Material anatomical entity that forms the outermost boundary of an anatomical structure. GO:0047213 anthocyanidin 3-O-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047213 MetaCyc:2.4.1.115-RXN|EC:2.4.1.115|RHEA:20093 3-GT activity|UDP-glucose:anthocyanidin/flavonol 3-O-glucosyltransferase activity|UDP-glucose:cyanidin-3-O-glucosyltransferase activity|UDP-glucose:anthocyanidin 3-O-D-glucosyltransferase activity|uridine diphosphoglucose-anthocyanidin 3-O-glucosyltransferase activity|UDP-D-glucose:anthocyanidin 3-O-beta-D-glucosyltransferase activity Catalysis of the reaction: anthocyanidin + UDP-D-glucose = anthocyanidin-3-O-D-glucoside + UDP. UBERON:0036214 rectosigmoid junction biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036214 rectosigmoid region An anatomical junction that is between the sigmoid colon and rectum. GO:0047212 2-coumarate O-beta-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047212 KEGG_REACTION:R03710|MetaCyc:2.4.1.114-RXN|EC:2.4.1.114|RHEA:10236 UDP-glucose:trans-2-hydroxycinnamate O-beta-D-glucosyltransferase activity|UDPglucose:trans-2-hydroxycinnamate O-beta-D-glucosyltransferase activity|UDPG:o-coumaric acid O-glucosyltransferase activity|uridine diphosphoglucose-o-coumarate glucosyltransferase activity Catalysis of the reaction: trans-2-coumarate + UDP-D-glucose = trans-beta-D-glucosyl-2-hydroxycinnamate + H(+) + UDP. UBERON:0036217 coelomic fluid biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036217 A bodily fluid that is located in the coelom. GO:0047211 alpha-1,4-glucan-protein synthase (ADP-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047211 MetaCyc:2.4.1.113-RXN|EC:2.4.1.113 1,4alpha-glucan-protein synthase (ADP-forming) activity|ADPglucose:protein 4-alpha-D-glucosyltransferase activity|adenosine diphosphoglucose-protein glucosyltransferase activity|ADP-glucose:protein 4-alpha-D-glucosyltransferase activity|ADPglucose:protein glucosyltransferase activity Catalysis of the reaction: ADP-D-glucose + protein = alpha-D-glucosyl-protein + ADP. CL:0002584 renal cortical epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002584 An epithelial cell of the kidney cortex. CL:0002586 retinal pigment epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002586 An epithelial cell of the retinal pigmented epithelium. CL:0002585 retinal blood vessel endothelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002585 A blood vessel endothelial cell that is part of the retina. GO:0047219 monoterpenol beta-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047219 MetaCyc:2.4.1.127-RXN|RHEA:11520|KEGG_REACTION:R02179|EC:2.4.1.127 UDPglucose:monoterpenol glucosyltransferase activity|UDPglucose:(-)-menthol O-beta-D-glucosyltransferase activity|UDP-glucose:(-)-menthol O-beta-D-glucosyltransferase activity|uridine diphosphoglucose-monoterpenol glucosyltransferase activity Catalysis of the reaction: (-)-menthol + UDP-D-glucose = (-)-menthyl beta-D-glucoside + H(+) + UDP. NCBITaxon:47570 Schizotrypanum organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_47570 CHEBI:74387 Ala-Gln zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74387 CHEBI:74389 Ala-Leu zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74389 CHEBI:74388 Ala-His zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74388 GO:0106243 syn-isopimara-7,15-diene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106243 RHEA:62188 Catalysis of the reaction: 9alpha-copalyl diphosphate = diphosphate + syn-isopimara-7,15-diene. GO:0047221 sn-glycerol-3-phosphate 2-alpha-galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047221 KEGG_REACTION:R00853|MetaCyc:2.4.1.137-RXN|EC:2.4.1.137|RHEA:14285 UDP-galactose:sn-glycerol-3-phosphate 2-alpha-D-galactosyltransferase activity|floridoside-phosphate synthase activity|FPS|UDPgalactose:sn-glycerol-3-phosphate 2-alpha-D-galactosyltransferase activity|floridoside phosphate synthetase activity|UDP-galactose, sn-3-glycerol phosphate:1->2' galactosyltransferase activity|UDP-galactose:sn-glycerol-3-phosphate-2-D-galactosyl transferase activity|floridoside phosphate synthase activity Catalysis of the reaction: sn-glycerol 3-phosphate + UDP-D-galactose = 2-(alpha-D-galactosyl)-sn-glycerol 3-phosphate + H(+) + UDP. GO:0047220 galactosylxylosylprotein 3-beta-galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047220 Reactome:R-HSA-4420365|Reactome:R-HSA-1889978|MetaCyc:2.4.1.134-RXN|RHEA:11780|EC:2.4.1.134 UDPgalactose:4-beta-D-galactosyl-O-beta-D-xylosylprotein 3-beta-D-galactosyltransferase activity|uridine diphosphogalactose-galactosylxylose galactosyltransferase activity|UDP-galactose:4-beta-D-galactosyl-O-beta-D-xylosylprotein 3-beta-D-galactosyltransferase activity|galactosyltransferase II activity Catalysis of the reaction: 4-beta-D-galactosyl-O-beta-D-xylosylprotein + UDP-galactose = 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein + UDP. GO:0106242 kolavenyl diphosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106242 RHEA:54676|EC:5.5.1.29 Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = (+)-kolavenyl diphosphate. GO:0106240 labd-13Z-ene-9,15,16-triol synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106240 RHEA:62192 Catalysis of the reaction:O2 + peregrinol + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + labd-13Z-ene-9,15,16-triol + oxidized [NADPH--hemoprotein reductase]. GO:0106247 negative regulation of poly(A)-specific ribonuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106247 Any process that stops, prevents or reduces the frequency, rate or extent of poly(A)-specific ribonuclease activity. GO:0106246 regulation of poly(A)-specific ribonuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106246 Any process that modulates the rate, frequency or extent of the catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP. GO:0106245 L-serine-phosphatidylethanolamine phosphatidyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106245 RHEA:27606|EC:2.7.8.29 Catalysis of the reaction: L-1-phosphatidylethanolamine + L-serine <=> L-1-phosphatidylserine + ethanolamine. GO:0106244 eupatolide synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106244 RHEA:57972|EC:1.14.14.169 Catalysis of the reaction: 8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + O2 + reduced [NADPH--hemoprotein reductase] = eupatolide + 2 H2O + oxidized [NADPH--hemoprotein reductase]. GO:0047229 13-hydroxydocosanoate 13-beta-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047229 RHEA:22316|EC:2.4.1.158|MetaCyc:HYDROXYDOCOSANOATE-TRANS-RXN UDP-glucose-13-hydroxydocosanoate glucosyltransferase activity|UDPglucose:13-hydroxydocosanoate 13-beta-D-glucosyltransferase activity|UDP-glucose:13-hydroxydocosanoic acid glucosyltransferase activity|13-glucosyloxydocosanoate 2'-beta-glucosyltransferase activity|UDP-glucose:13-hydroxydocosanoate 13-beta-D-glucosyltransferase activity|uridine diphosphoglucose-hydroxydocosanoate glucosyltransferase activity Catalysis of the reaction: 13-hydroxydocosanoate + UDP-D-glucose = 13-beta-D-glucosyloxydocosanoate + UDP. GO:0047228 1,2-diacylglycerol 3-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047228 MetaCyc:2.4.1.157-RXN|EC:2.4.1.157 UDP-glucose:1,2-diacylglycerol 3-D-glucosyltransferase activity|UDP-glucose-diacylglycerol glucosyltransferase activity|UDPglucose:diacylglycerol glucosyltransferase activity|UDP-glucose:1,2-diacylglycerol glucosyltransferase activity|uridine diphosphoglucose-diacylglycerol glucosyltransferase activity|UDPglucose:1,2-diacylglycerol 3-D-glucosyltransferase activity Catalysis of the reaction: 1,2-diacylglycerol + UDP-D-glucose = 3-D-glucosyl-1,2-diacylglycerol + UDP. GO:0106249 Nicalin-NOMO complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0106249 A protein complex regulating Nodal signaling. Subunits are highly conserved in vertebrates and include Nicalin, NOMO and TMEM147. UBERON:0036224 corticobulbar and corticospinal tracts biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036224 pyramidal tract The corticobulbar and corticospinal tracts combined. GO:0047227 indolylacetyl-myo-inositol galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047227 RHEA:21148|KEGG_REACTION:R04334|MetaCyc:2.4.1.156-RXN|EC:2.4.1.156 uridine diphosphogalactose-indolylacetylinositol galactosyltransferase activity|indol-3-ylacetyl-myo-inositol galactoside synthase activity|UDP-galactose:(indol-3-yl)acetyl-myo-inositol 5-O-D-galactosyltransferase activity|UDP-galactose:indol-3-ylacetyl-myo-inositol 5-O-D-galactosyltransferase activity Catalysis of the reaction: 1L-1-O-(indol-3-yl)acetyl-myo-inositol + UDP-D-galactose = 5-O-(indol-3-ylacetyl)-myo-inositol D-galactoside + H(+) + UDP. GO:0106248 positive regulation of poly(A)-specific ribonuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106248 Any process that activates or increases the frequency, rate or extent of poly(A)-specific ribonuclease activity. GO:0047226 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0047226 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047225 MetaCyc:2.4.1.148-RXN|EC:2.4.1.148|RHEA:16552 O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IV activity|core 6-beta-GalNAc-transferase B activity|UDP-N-acetyl-D-glucosamine:O-oligosaccharide-glycoprotein (N-acetyl-D-glucosamine to N-acetyl-D-galactosamine of N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-D-galactosaminyl-R) beta-1,6-N-acetyl-D-glucosaminyltransferase activity|uridine diphosphoacetylglucosamine-mucin beta(1->6)-acetylglucosaminyltransferase B|core 6beta-GalNAc-transferase B|core 4 beta6-GalNAc-transferase activity Catalysis of the reaction: N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-D-galactosaminyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,3)-N-acetyl-D-galactosaminyl-R + UDP. GO:0047224 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047224 MetaCyc:2.4.1.147-RXN|EC:2.4.1.147|RHEA:14252 O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III activity|mucin core 3 beta3-GlcNAc-transferase activity|uridine diphosphoacetylglucosamine-mucin beta(1->3)-acetylglucosaminyltransferase activity|core 3-beta-GlcNAc-transferase activity|UDP-N-acetyl-D-glucosamine:O-glycosyl-glycoprotein (N-acetyl-D-glucosamine to N-acetyl-D-galactosaminyl-R) beta-1,3-N-acetyl-D-glucosaminyltransferase activity|core 3beta-GlcNAc-transferase activity Catalysis of the reaction: N-acetyl-D-galactosalaminyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-D-galactosaminyl-R + UDP. UBERON:0036225 respiratory system gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036225 Any gland that is part os the respiratory system. GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047223 Reactome:R-HSA-5617096|MetaCyc:2.4.1.146-RXN|EC:2.4.1.146|Reactome:R-HSA-5617037 UDP-N-acetyl-D-glucosamine:O-glycosyl-glycoprotein (N-acetyl-D-glucosamine to -D-galactose of beta-D-galactosyl-1,3-(N-acetyl-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R) beta-1,3-N-acetyl-D-glucosaminyltransferase activity|uridine diphosphoacetylglucosamine-mucin beta(1->3)-acetylglucosaminyltransferase (elongating)|elongation 3beta-GalNAc-transferase activity|elongation 3-beta-GalNAc-transferase activity|O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II activity Catalysis of the reaction: beta-D-galactosyl-1,3-(N-acetyl-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R + UDP. GO:0047222 mannotetraose 2-alpha-N-acetylglucosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047222 RHEA:13705|MetaCyc:2.4.1.138-RXN|EC:2.4.1.138 alpha-N-acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:mannotetraose alpha-N-acetyl-D-glucosaminyltransferase activity|uridine diphosphoacetylglucosamine mannoside alpha1->2-alphacetylglucosaminyltransferase activity Catalysis of the reaction: 1,3-alpha-D-mannosyl-1,2-alpha-D-mannosyl-1,2-alpha-D-mannosyl-D-mannose + UDP-N-acetyl-D-glucosamine = 1,3-alpha-D-mannosyl-1,2-(N-acetyl-alpha-D-glucosaminyl-alpha-D-mannosyl)-1,2-alpha-D-mannosyl-D-mannose + UDP. CL:0002597 smooth muscle cell of bladder biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002597 A smooth muscle cell of the bladder. CL:1000123 metanephric nephron tubule epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000123 CL:0002599 smooth muscle cell of the esophagus biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002599 A smooth muscle cell of the esophagus. CHEBI:74390 Ala-Thr zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74390 CL:0002598 bronchial smooth muscle cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002598 CHEBI:74392 Gly-Gln zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74392 CHEBI:74391 Gly-Asn zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74391 CHEBI:74394 Met-Ala zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74394 CHEBI:74393 Gly-Met zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74393 CHEBI:74396 (9Z,11E)-octadecadienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74396 CHEBI:74395 (11E)-octadecenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74395 CL:0002591 smooth muscle cell of the pulmonary artery biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002591 A smooth muscle of the pulmonary artery. GO:0106250 DNA-binding transcription repressor activity, RNA polymerase III-specific biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106250 A DNA-binding transcription factor activity that represses or decreases the transcription of specific genes sets transcribed by RNA polymerase III. CHEBI:74398 (9Z)-heptadecenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74398 CHEBI:74397 heptadecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74397 CL:0002590 smooth muscle cell of the brain vasculature biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002590 A vascular associated smooth muscle cell of the brain vasculature. CL:0002592 smooth muscle cell of the coronary artery biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002592 A smooth muscle cell of the coronary artery. CHEBI:74399 (15Z,18Z,21Z,24Z,27Z)-3-oxotriacontapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74399 GO:0106254 lipid sensor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106254 Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of a lipid. GO:0047232 galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,6-N-acetylglucosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047232 MetaCyc:2.4.1.164-RXN|EC:2.4.1.164 uridine diphosphoacetylglucosamine-acetyllactosaminide beta1->6-acetylglucosaminyltransferase|UDP-N-acetyl-D-glucosamine:D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide beta-1,6-N-acetylglucosaminyltransferase activity Catalysis of the reaction: D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide + UDP-N-acetyl-D-glucosamine = N-acetyl-D-glucosaminyl-1,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosyceramide + UDP. GO:0106253 positive regulation of DNA strand resection involved in replication fork processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106253 Any process that activates or increases the frequency, rate or extent of DNA strand resection involved in replication fork processing. GO:0047231 pyridoxine 5'-O-beta-D-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047231 MetaCyc:2.4.1.160-RXN|EC:2.4.1.160|KEGG_REACTION:R01912|RHEA:20177 UDP-glucose-pyridoxine glucosyltransferase activity|UDP-glucose:pyridoxine 5'-O-beta-D-glucosyltransferase activity|UDP-glucose:pyridoxine 5'-O-beta-glucosyltransferase activity|uridine diphosphoglucose-pyridoxine 5'-beta-glucosyltransferase activity|UDPglucose:pyridoxine 5'-O-beta-D-glucosyltransferase activity Catalysis of the reaction: pyridoxine + UDP-D-glucose = 5'-O-beta-D-glucosylpyridoxine + H(+) + UDP. GO:0047230 flavonol-3-O-glucoside L-rhamnosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047230 EC:2.4.1.159|RHEA:22528|MetaCyc:2.4.1.159-RXN uridine diphosphorhamnose-flavonol 3-O-glucoside rhamnosyltransferase activity|UDP-rhamnose:flavonol 3-O-glucoside rhamnosyltransferase activity|UDP-L-rhamnose:flavonol-3-O-D-glucoside 6''-O-L-rhamnosyltransferase activity Catalysis of the reaction: flavonol 3-O-D-glucoside + UDP-L-rhamnose = flavonol 3-O-L-rhamnosylglucoside + UDP. GO:0106251 N4-acetylcytidine amidohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106251 RHEA:62932 Catalysis of the reaction N4-acetylcytidine +H2O = cytidine + acetate. GO:0106258 L-serine-phosphatidylcholine phosphatidyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106258 RHEA:45088 Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phosphocholine + L-serine = 1,2-diacyl-sn-glycero-3-phospho-L-serine + choline. GO:0106257 glycerol-3-phosphate dehydrogenase [NADP+] activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106257 RHEA:11096 Catalysis of the reaction: sn-glycerol 3-phosphate + NADP+ = glycerone phosphate + NADH + H+. GO:0106256 hydroperoxy icosatetraenoate dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106256 EC:4.2.1.152|RHEA:55556 A hydroperoxy icosatetraenoate <=> an oxoicosatetraenoate + H(2)O. GO:0106255 hydroperoxy icosatetraenoate isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106255 EC:5.4.4.7|RHEA:55560 A hydroperoxy icosatetraenoate <=> a hydroxy epoxy icosatrienoate. GO:0047239 hydroxymandelonitrile glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047239 MetaCyc:2.4.1.178-RXN|RHEA:15961|EC:2.4.1.178|KEGG_REACTION:R02709 cyanohydrin glucosyltransferase activity|UDPglucose:4-hydroxymandelonitrile glucosyltransferase activity|UDP-glucose:4-hydroxymandelonitrile glucosyltransferase activity Catalysis of the reaction: 4-hydroxymandelonitrile + UDP-D-glucose = H(+) + taxiphyllin + UDP. GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047238 Reactome:R-HSA-1971482|MetaCyc:2.4.1.175-RXN|Reactome:R-HSA-3595176|Reactome:R-HSA-9632033|EC:2.4.1.175|Reactome:R-HSA-1971487 UDP-N-acetyl-D-galactosamine:beta-D-glucuronosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity|N-acetylgalactosaminyltransferase II activity|uridine diphosphoacetylgalactosamine-chondroitin acetylgalactosaminyltransferase II activity|glucuronyl-N-acetylgalactosaminylproteoglycan beta-1,4-N-acetylgalactosaminyltransferase activity|UDP-N-acetyl-D-galactosamine:D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan beta-1,4-N-acetylgalactosaminyltransferase activity|glucuronyl-N-acetylgalactosaminylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity|chondroitin synthase activity Catalysis of the reaction: D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-1,4-beta-D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan + UDP. GO:0106259 cell-to-cell migration in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106259 The directional movement of a symbiont from one host cell to another. GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047237 RHEA:23464|MetaCyc:2.4.1.174-RXN|EC:2.4.1.174 glucuronylgalactosylproteoglycan beta-1,4-N-acetylgalactosaminyltransferase activity|N-acetylgalactosaminyltransferase I activity|uridine diphosphoacetylgalactosamine-chondroitinacetylgalactosaminyltransferase I activity|uridine diphosphoacetylgalactosamine-chondroitin acetylgalactosaminyltransferase I|UDP-N-acetyl-D-galactosamine:D-glucuronyl-1,3-beta-D-galactosyl-proteoglycan beta-1,4-N-acetylgalactosaminyltransferase activity Catalysis of the reaction: D-glucuronyl-1,3-beta-D-galactosylproteoglycan + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-1,4-beta-D-glucuronyl-1,3-beta-D-galactosylproteoglycan + UDP. GO:0047236 methyl-ONN-azoxymethanol beta-D-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047236 MetaCyc:2.4.1.171-RXN|EC:2.4.1.171|RHEA:20205 cycasin synthase activity|UDP-glucose:methyl-ONN-azoxymethanol beta-D-glucosyltransferase activity|UDPglucose-methylazoxymethanol glucosyltransferase activity|uridine diphosphoglucose-methylazoxymethanol glucosyltransferase activity|methyl-ONN-azoxymethanol glucosyltransferase activity Catalysis of the reaction: methylazoxymethanol + UDP-D-glucose = H+ + cycasin + UDP. GO:0047235 sucrose 6F-alpha-galactotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047235 RHEA:10088|MetaCyc:2.4.1.167-RXN|EC:2.4.1.167 UDP-galactose:sucrose 6F-alpha-D-galactosyltransferase activity|UDPgalactose:sucrose 6fru-alpha-galactosyltransferase activity|sucrose 6F-alpha-galactosyltransferase activity|uridine diphosphogalactose-sucrose 6F-alpha-galactosyltransferase activity|sucrose 6(F)-alpha-galactosyltransferase activity|UDPgalactose:sucrose 6F-alpha-D-galactosyltransferase activity Catalysis of the reaction: sucrose + UDP-galactose = 6F-alpha-D-galactosylsucrose + UDP. GO:0047234 raffinose-raffinose alpha-galactotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047234 RHEA:14125|MetaCyc:2.4.1.166-RXN|EC:2.4.1.166 raffinose:raffinose alpha-D-galactosyltransferase activity|raffinose-raffinose alpha-galactosyltransferase activity|raffinose (raffinose donor) galactosyltransferase activity|raffinose-raffinose a-galactosyltransferase activity|raffinose:raffinose alpha-galactosyltransferase activity Catalysis of the reaction: 2 raffinose = sucrose + 1F-alpha-D-galactosylraffinose. GO:0047233 N-acetylneuraminylgalactosylglucosylceramide beta-1,4-N-acetylgalactosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047233 MetaCyc:2.4.1.165-RXN|EC:2.4.1.165|RHEA:13569 uridine diphosphoacetylgalactosamine-acetylneuraminyl(alpha2->3)galactosyl(beta1->4)glucosyl beta1->4-acetylgalactosaminyltransferase activity|UDP-N-acetyl-D-galactosamine:N-acetylneuraminyl-2,3-alpha-D-galactosyl-1,4-beta-D-glucosylceramide beta-1,4-N-acetylgalactosaminyltransferase activity Catalysis of the reaction: N-acetylneuraminyl-2,3-alpha-D-galactosyl-1,4-beta-D-glucosylceramide + UDP-N-acetylgalactosamine = N-acetyl-beta-D-galactosaminyl-1,4-(N-acetyl-alpha-neuraminyl-2,3)-beta-D-galactosyl-1,4-beta-D-glucosylceramide + UDP. CL:0002563 intestinal epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002563 An epithelial cell of the intestine. CL:1000155 Malpighian tubule stellate cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000155 Malpighian tubule Type II cell A specialized epithelial secretory cell that moves chloride ions and water across the tubule epithelium. GO:0106261 tRNA uridine(34) acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106261 RHEA:61020 Catalysis of the reaction: acetyl-CoA + H2O + S-adenosyl-L-methionine + uridine(34) in tRNA = 5'-deoxyadenosine + carboxymethyluridine(34) in tRNA + CoA + 2 H(+) + L-methionine. GO:0106260 DNA-DNA tethering activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106260 double-stranded DNA bridging|dsDNA bridging The binding activity of a protein or complex that connects two spatially separated regions of DNA sequence. GO:0047243 flavanone 7-O-beta-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047243 MetaCyc:2.4.1.185-RXN|EC:2.4.1.185 UDP-glucose:flavanone 7-O-beta-D-glucosyltransferase activity|uridine diphosphoglucose-flavanone 7-O-glucosyltransferase activity|naringenin 7-O-glucosyltransferase activity|UDPglucose:flavanone 7-O-beta-D-glucosyltransferase activity|hesperetin 7-O-glucosyl-transferase activity Catalysis of the reaction: a flavanone + UDP-D-glucose = a flavanone 7-O-beta-D-glucoside + UDP. GO:0106265 THPH synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106265 RHEA:64352 polyketide syntase Catalysis of the reaction: 3 H+ + hexanoyl-CoA + 3 malonyl-CoA = 2,4,6-trihydroxyphenylhexan-1-one + 3 CO2 + 4 CoA. GO:0047242 hydroxyanthraquinone glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047242 MetaCyc:2.4.1.181-RXN|EC:2.4.1.181 UDPglucose:hydroxyanthraquinone O-glucosyltransferase activity|uridine diphosphoglucose-anthraquinone glucosyltransferase activity|anthraquinone-specific glucosyltransferase activity|UDP-glucose:hydroxyanthraquinone O-glucosyltransferase activity Catalysis of the reaction: a hydroxyanthraquinone + UDP-D-glucose = a glucosyloxyanthraquinone + UDP. GO:0106264 protein serine kinase activity (using GTP as donor) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106264 Catalysis of the reactions: GTP + L-seryl-[protein] = GDP + H(+) + O-phospho-L-seryl-[protein]. GO:0106263 1-acylglycerophosphoserine O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106263 RHEA:33191 Catalysis of the reaction:a 1-acyl-sn-glycero-3-phospho-L-serine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + CoA. GO:0047241 lipopolysaccharide N-acetylmannosaminouronosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047241 RHEA:28366|MetaCyc:2.4.1.180-RXN|EC:2.4.1.180 ManNAcA transferase activity|LPS N-acetylmannosaminouronosyltransferase activity|uridine diphosphoacetylmannosaminuronate-acetylglucosaminylpyrophosphorylundecaprenol acetylmannosaminuronosyltransferase activity|UDP-N-acetyl-beta-D-mannosaminouronate:lipopolysaccharide N-acetyl-beta-D-mannosaminouronosyltransferase activity Catalysis of the reaction: lipopolysaccharide + UDP-N-acetylmannosaminouronate = N-acetyl-beta-D-mannosaminouronosyl-1,4-lipopolysaccharide + UDP. GO:0047240 lactosylceramide beta-1,3-galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047240 MetaCyc:2.4.1.179-RXN|KEGG_REACTION:R04431|RHEA:18413|EC:2.4.1.179 UDP-galactose:D-galactosyl-1,4-beta-D-glucosyl-R beta-1,3-galactosyltransferase activity|uridine diphosphogalactose-lactosylceramide beta1->3-galactosyltransferase activity|UDPgalactose:D-galactosyl-1,4-beta-D-glucosyl-R beta-1,3-galactosyltransferase activity Catalysis of the reaction: D-galactosyl-(1->4)-beta-D-glucosyl-R + UDP-D-galactose = D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-R + H(+) + UDP. GO:0106262 1-acylglycerophosphoethanolamine O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106262 RHEA:32995 Catalysis of the reaction: a 1-acyl-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA. GO:0106268 3,5-dichloro-THPH methyl transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106268 RHEA:48396 DIF-1 syntase Catalysis of the reaction: (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one + S-adenosyl-L-methionine = 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one + H+ + S-adenosyl-L-homocysteine. GO:0106267 3,5 dichloro-THPH synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106267 RHEA:64360 Catalysis of the reaction: (3-chloro-2,4,6-trihydroxyphenyl)hexan-1-one + chloride + FADH2 + O2 = (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one + FAD + 2 H2O. UBERON:0036242 post-embryonic notochord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036242 A notochord that has persisted beyond the embryonic stage. GO:0106266 3-chloro THPH synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106266 RHEA:64356 Catalysis of the reaction: 2,4,6-trihydroxyphenylhexan-1-one + chloride + FADH2 + O2 = (3-chloro-2,4,6-trihydroxyphenyl)hexan-1-one + FAD + H+ + 2 H2O. UBERON:0012292 embryonic cloacal fold biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012292 cloacal fold One of the pair of mesenchymal swellings (folds) located on either side of the cloacal membrane during the indifferent stage of embryonic development; cranial to the cloacal membrane the folds unite to form the genital tubercle; caudally the folds are subdivided into urogenital folds anteriorly and anal folds posteriorly UBERON:0012299 mucosa of urethra biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012299 tunica mucosa urethrae|mucous membrane of urethra|urethral mucosa A mucosa that is part of a urethra. UBERON:0036244 secretion of serous membrane biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036244 serous sac fluid|serous fluid A transudate found in the serous sac. UBERON:0036243 vaginal fluid biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036243 vaginal discharge|vaginal secretion Fluid that lines the vaginal walls that consists of multiple secretions that collect in the vagina from different glands. GO:0047249 sarsapogenin 3-beta-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047249 KEGG_REACTION:R04359|RHEA:14461|MetaCyc:2.4.1.193-RXN|EC:2.4.1.193 UDP-glucose:(25S)-5beta-spirostan-3beta-ol 3-O-beta-D-glucosyltransferase activity|UDPglucose:(25S)-5beta-spirostan-3beta-ol 3-O-beta-D-glucosyltransferase activity|sarsapogenin 3beta-glucosyltransferase activity|uridine diphosphoglucose-sarsapogenin glucosyltransferase activity Catalysis of the reaction: (25S)-5beta-spirostan-3beta-ol + UDP-D-glucose = (25S)-5beta-spirostan-3beta-yl beta-D-glucoside + H(+) + UDP. UBERON:0036245 parenchyma of mammary gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036245 parenchyma of lactiferous gland|mammary gland parenchyma|lactiferous gland parenchyma Parenchymal tissue that consists of the alveoli, grape-like clusters where milk is stored, and branching ducts, which are tubular canals carrying gladular secretions. GO:0047248 nuatigenin 3-beta-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047248 KEGG_REACTION:R04577|RHEA:19329|MetaCyc:2.4.1.192-RXN|EC:2.4.1.192 UDPglucose:(20S,22S,25S)-22,25-epoxyfurost-5-ene-3beta,26-diol 3-O-beta-D-glucosyltransferase activity|nuatigenin 3beta-glucosyltransferase activity|uridine diphosphoglucose-nuatigenin glucosyltransferase activity|UDP-glucose:(20S,22S,25S)-22,25-epoxyfurost-5-ene-3beta,26-diol 3-O-beta-D-glucosyltransferase activity Catalysis of the reaction: nuatigenin + UDP-D-glucose = H(+) + nuatigenin 3-beta-D-glucopyranoside + UDP. GO:0047247 luteolin-7-O-diglucuronide 4'-O-glucuronosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047247 EC:2.4.1.191|KEGG_REACTION:R06828|RHEA:22116|MetaCyc:2.4.1.191-RXN uridine diphosphoglucuronate-luteolin 7-O-diglucuronide glucuronosyltransferase activity|UDPglucuronate:luteolin-7-O-beta-D-diglucuronide 4'-O-glucuronosyltransferase activity|LDT|UDP-glucuronate:luteolin 7-O-diglucuronide-glucuronosyltransferase activity|UDP-glucuronate:luteolin-7-O-beta-D-diglucuronide 4'-O-glucuronosyltransferase activity|UDPglucuronate:luteolin 7-O-diglucuronide-4'-O-glucuronosyl-transferase activity Catalysis of the reaction: luteolin 7-O-[(beta-D-glucosiduronate)-(1->2)-(beta-D-glucosiduronate)] + UDP-alpha-D-glucuronate = H(+) + luteolin 7-O-[(beta-D-glucosiduronate)-(1->2)-(beta-D-glucosiduronate)] 4'-O-beta-D-glucosiduronate + UDP. UBERON:0036248 joint of auditory ossicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036248 auditory ossicle joint|joint of auditory ossicles|auditory ossicles joint Any synovial joint that connects auditory ossicles. GO:0047246 luteolin-7-O-glucuronide 7-O-glucuronosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047246 EC:2.4.1.190|KEGG_REACTION:R06827|RHEA:14149|MetaCyc:2.4.1.190-RXN uridine diphosphoglucuronate-luteolin 7-O-glucuronide glucuronosyltransferase activity|LMT activity|UDP-glucuronate:luteolin 7-O-glucuronide-glucuronosyltransferase activity|luteolin-7-O-glucuronide 2''-O-glucuronosyltransferase activity|UDP-glucuronate:luteolin-7-O-beta-D-glucuronide 2''-O-glucuronosyltransferase activity Catalysis of the reaction: luteolin 7-O-beta-D-glucosiduronate + UDP-alpha-D-glucuronate = H(+) + luteolin 7-O-[(beta-D-glucosiduronate)-(1->2)-(beta-D-glucosiduronate)] + UDP. GO:0047245 N-acetylglucosaminyldiphosphoundecaprenol glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047245 RHEA:20952|MetaCyc:2.4.1.188-RXN|EC:2.4.1.188 uridine diphosphoglucose-acetylglucosaminylpyrophosphorylundecaprenol glucosyltransferase activity|UDP-D-glucose:N-acetylglucosaminyl pyrophosphorylundecaprenol glucosyltransferase activity|UDP-glucose:N-acetyl-D-glucosaminyldiphosphoundecaprenol 4-beta-D-glucosyltransferase activity|UDPglucose:N-acetyl-D-glucosaminyldiphosphoundecaprenol 4-beta-D-glucosyltransferase activity Catalysis of the reaction: N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP-D-glucose = beta-D-glucosyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP. GO:0047244 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047244 MetaCyc:TEICHOICSYN2-RXN|RHEA:16053|EC:2.4.1.187 uridine diphosphoacetyl-mannosamineacetylglucosaminylpyrophosphorylundecaprenol acetylmannosaminyltransferase activity|N-acetylmannosaminyltransferase activity|UDP-N-acetylmannosamine:N-acetylglucosaminyl diphosphorylundecaprenol N-acetylmannosaminyltransferase activity|UDP-N-acetyl-D-mannosamine:N-acetyl-beta-D-glucosaminyldiphosphoundecaprenol beta-1,4-N-acetylmannosaminyltransferase activity Catalysis of the reaction: N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP-N-acetyl-D-mannosamine = N-acetyl-beta-D-mannosaminyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP. CL:0002573 Schwann cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002573 A glial cell that ensheathes axons of neuron in the peripheral nervous system and are necessary for their maintainance and function. CL:1000147 heart valve cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000147 CL:0002575 central nervous system pericyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002575 A pericyte of the central nervous system. CL:0002574 stromal cell of pancreas biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002574 A stromal cell of the pancreas. CL:0002577 placental epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002577 An epithelial cell of the placenta. CL:1000143 lung goblet cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000143 GO:0106272 protein localization to ERGIC biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106272 A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum-Golgi intermediate compartment (ERGIC). GO:0106271 D-arabinose 1-dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106271 RHEA:21892|EC:1.1.1.117 Catalysis of the reaction: D-arabinose + NADP+ = D-arabinono-1,4-lactone + NADPH. CL:0002571 hepatic mesenchymal stem cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002571 A mesenchymal stem cell of liver. CL:0002570 mesenchymal stem cell of adipose biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002570 A mesenchymal stem cell of adipose tissue. CHEBI:25336 methylpropanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25336 CHEBI:49302 2-hydroxy monocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49302 CHEBI:49305 5,6alpha-epoxy-5alpha-cholestan-3beta-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49305 CHEBI:25333 pretetramide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25333 UBERON:0012321 deep cervical artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012321 profunda cervicalis The deep cervical artery (Profunda cervicalis) is an artery of the neck. UBERON:0012320 cervical artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012320 An artery of the neck CHEBI:64940 inositol phosphophytoceramide (t18:0)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64940 CL:1000217 growth plate cartilage chondrocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000217 CHEBI:49301 hydrindane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49301 UBERON:0012317 vagina orifice biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012317 introitus of vagina|vagina opening|vaginal orifice|ostium vaginae|orifice of vagina|introitus|introitus|opening of vagina|vaginal introitus The median slit located inferior and posterior to the external urethral orifice in the female; the exit for menstrual flow and birth and the entrance for the penis during sexual intercourse; the size and appearance of the vaginal orifice varies inversely with that of the hymen (G. membrane), a thin fold of mucous membrane that surrounds the vaginal orifice UBERON:0012316 primitive palate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012316 palate Roof of the buccal cavity, formed from the fusion of vomer, pterygoid, parasphenoid, palatine, ectopterygoid. CHEBI:64942 3-(4-hydroxycyclohex-2-en-1-ylidene)pyruvic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64942 CHEBI:64941 inositol phosphodihydroceramide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64941 CHEBI:64948 pyrrolizidine alkaloid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64948 CHEBI:64947 anti-HIV-1 agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64947 CHEBI:64946 anti-HIV agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64946 CHEBI:64945 sn-glycero-3-phosphoserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64945 CHEBI:25347 methyluridine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25347 CHEBI:25345 methyltetrahydrofolate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25345 CHEBI:25348 methylxanthine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25348 UBERON:0036301 vasculature of spleen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036301 UBERON:0012314 embryonic facial prominence biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012314 facial primordium|primordium of face|embryonic facial process One of five swellings formed during the development of the face CHEBI:64951 anti-HBV agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64951 UBERON:0036303 vasculature of central nervous system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036303 CHEBI:64950 pyrrolizidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64950 UBERON:0036302 vasculature of central nervous system plus retina biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036302 UBERON:0012312 maxillary process ectoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012312 UBERON:0036304 anatomical border biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036304 An anatomical structure that is located along the line dividing two regions of an anatomical structure. CHEBI:25340 methylpyridines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25340 CHEBI:15999 (4-hydroxyphenyl)pyruvic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15999 CHEBI:15998 (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl trihydrogen diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15998 CHEBI:40968 astaxanthin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_40968 CHEBI:64953 anti-HSV-1 agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64953 CHEBI:64952 anti-HSV agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64952 CHEBI:64958 N-(2-hydroxyhexacosanoyl)phytosphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64958 CHEBI:15994 5alpha-androstane-3,17-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15994 CHEBI:15997 2-methylpropanamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15997 CHEBI:15996 GTP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15996 CHEBI:64956 sn-glycero-3-phospho-(1'-sn-glycerol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64956 CHEBI:15993 N-acyl-D-glucosamine 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15993 CHEBI:15992 1-hydroxy-2-naphthoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15992 CHEBI:25312 3-methylmalic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25312 CHEBI:25311 methylisocitric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25311 UBERON:0002979 Purkinje cell layer of cerebellar cortex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002979 reticulatum thalami (Hassler)|cerebellum Purkinje cell layer|nucleus reticulatus (thalami)|cerebellum Purkinje layer|reticular nucleus thalamus (Arnold)|cerebellar Purkinje cell layer|nucleus reticularis|nucleus thalamicus reticularis|Purkinje cell layer|nuclei reticulares (thalami) The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells. CL:1000239 anterior lateral line nerve glial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000239 CHEBI:64962 glucobrassicin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64962 CHEBI:64961 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64961 CL:1000236 posterior lateral line nerve glial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000236 NCBITaxon:166126 Seriata organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_166126 CHEBI:64964 EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64964 CHEBI:64969 inositol phosphodihydroceramide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64969 CHEBI:64967 4-carboxyzymosterol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64967 CHEBI:25324 methylnaphthalenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25324 CHEBI:25322 methylmercury compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25322 UBERON:0002967 cingulate gyrus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002967 cingulate region|gyri cinguli|cingulate area|falciform lobe|upper limbic gyrus|cingular gyrus One of the convolutions on the medial surface of the cerebral hemisphere. It surrounds the rostral part of the brain and interhemispheric commissure and forms part of the limbic system. (MSH) One of three essential structures comprising the limbic lobe, the other two being the hippocampus and parahippocampal gyrus. (CSP) CHEBI:64973 bicyclic nitroimidazole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64973 CHEBI:64971 ergosta-5,7,22,24(28)-tetraen-3beta-yl acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64971 CHEBI:64970 inositol phosphophytoceramide (t18:0) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64970 CHEBI:64977 cichorine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64977 CHEBI:64976 ergosteryl palmitate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64976 PR:000012705 polymeric immunoglobulin receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000012705 PIGR|PIgR|poly-Ig receptor|hepatocellular carcinoma-associated protein TB6 A protein that is a translation product of the human PIGR gene or a 1:1 ortholog thereof. CL:1000223 lung neuroendocrine cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000223 CHEBI:64975 lanosteryl palmitate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64975 CL:1000222 stomach neuroendocrine cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000222 CHEBI:64974 (-)-microperfuranone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64974 UBERON:0002973 parahippocampal gyrus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002973 gyrus parahippocampalis|hippocampal gyrus|gyrus parahippocampi|gyrus hippocampi|hippocampal convolution Component of the temporal lobe on the mesial surface, posterior to the entorhinal cortex. The rostral and caudal boundaries are the posterior end of the netorhinal cortex and the caudal portion of the hippocampus, respectively. The medial boudnary is designated as the medial aspect off the temporal lobe and the lateral boundary is the collateral sulcus (Christine Fennema-Notestine). UBERON:0002974 molecular layer of cerebellar cortex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002974 thalamic fiber tracts|fasciculi thalami|cerebellum molecular cell layer|cerebellum molecular layer|cerebellar molecular layer|stratum moleculare corticis cerebelli The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells GO:0106078 histone succinyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106078 Catalysis of the reaction: succinyl-CoA + histone = CoA + succinyl-histone. GO:0106077 histone succinylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106077 The modification of a histone by the addition of an succinyl group. GO:0106076 peptide-lysine-N-succinyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106076 Catalysis of the reaction: succinyl-CoA + lysine in peptide = CoA + N-succinyl-lysine-peptide. CHEBI:74305 (8Z,11Z,14Z,17Z,20Z,23Z)-3-oxohexacosahexaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74305 GO:0106075 peptide N-succinyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106075 Catalysis of the acetylation of an amino acid residue of a peptide or protein, according to the reaction: succinyl-CoA + peptide = CoA + N-succinylpeptide. CHEBI:74304 (6Z,9Z,12Z,15Z,18Z,21Z)-3-oxotetracosahexaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74304 CHEBI:74307 heptadecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74307 UBERON:0012361 internal anal region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012361 CHEBI:74306 (8Z,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74306 UBERON:0012360 bone of jaw biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012360 jaw bone A bone element that is part of a jaw region. CHEBI:74309 pentadecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74309 CHEBI:74308 (9Z)-heptadecenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74308 CHEBI:64980 gammaGluCys(IAN)Gly biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64980 UBERON:0012367 muscle layer of intestine biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012367 smooth muscle of intestine|muscularis externa of intestine|intestinal muscularis propria A muscle layer that is part of an intestine. CHEBI:64982 2-acyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64982 CHEBI:64981 gammaGluCys(IAN)Gly(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64981 CHEBI:15966 D-glutamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15966 CHEBI:64988 L-Cys(IAN) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64988 CHEBI:15965 D-hexose phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15965 CHEBI:64987 S-conjugate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64987 CHEBI:15968 3-guanidinopropanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15968 UBERON:0012359 pedal digitopodium bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012359 bone of hindlimb digitopodium A bone that is part of a the pedal digitopodium skeleton - i.e. the toes or the metatarsal skeleton. CHEBI:64985 bioconjugate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64985 CHEBI:15961 O-phospho-L-homoserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15961 CHEBI:15964 cyclohexylsulfamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15964 CHEBI:15963 ribitol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15963 GO:0106081 maltose import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106081 The directed movement of maltose from outside of a cell, across the plasma membrane and into the cytosol. GO:0106080 GATOR1 complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106080 Interacting selectively and non-covalently with the GATOR1 complex. CHEBI:15960 O-acetylcarnitinium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15960 GO:0106084 mitotic nuclear membrane microtubule tethering complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0106084 IntAct:EBI-16412392 Mps2-Bbp1-Spc29 complex|nuclear membrane mitotic spindle pole body tethering complex A protein complex capable of interacting with the spindle pole body and the nuclear envelope, in order to embed the spindle pole body in the nuclear envelope at fusion sites of the inner and outer nuclear membrane. GO:0106083 nuclear membrane protein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0106083 Any protein complex that is part of the nuclear membrane. CHEBI:74301 wybutosine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74301 GO:0106082 sucrose import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106082 The directed movement of sucrose from outside of a cell, across the plasma membrane and into the cytosol. CHEBI:74300 wybutosine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74300 GO:0106089 negative regulation of cell adhesion involved in sprouting angiogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106089 Any process that stops, prevents or reduces the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis. GO:0106088 regulation of cell adhesion involved in sprouting angiogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106088 Any process that modulates the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis. CHEBI:25302 methyl glycoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25302 CHEBI:74313 (12Z,15Z,18Z,21Z,24Z,27Z)-3-oxotriacontahexaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74313 CHEBI:74316 (14Z,17Z,20Z,23Z,26Z,29Z)-3-oxodotriacontahexaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74316 CHEBI:74315 (12Z,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74315 CHEBI:74318 (16Z,19Z,22Z,25Z,28Z,31Z)-3-oxotetratriacontahexaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74318 CHEBI:25307 methylguanosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25307 CHEBI:74317 (14Z,17Z,20Z,23Z,26Z,29Z)-dotriacontahexaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74317 CHEBI:74319 (16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74319 UBERON:0012354 acropodium region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012354 set of digits|acropodial segment of autopod|acropodial region|acropodial limb segment The segment of the autopod that is distal to the metapodial region and consists of the digits. CHEBI:64991 mannosylinositol phosphophytoceramide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64991 UBERON:0012353 fin skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012353 skeleton of fin Skeletal subdivision consisting of all the skeletal elements in a single fin. CHEBI:39949 triphosphoric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39949 UBERON:0012358 manual digitopodium bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012358 bone of forelimb digitopodium A bone that is part of a the manual digitopodium skeleton - i.e. the fingers or the metacarpal skeleton. CHEBI:64995 EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64995 UBERON:0012357 digitopodium bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012357 digit bone A bone that is part of a the digitopodium skeleton - i.e. the acropodial skeleton or the metapodial skeleton. CHEBI:64994 inositol phosphophytoceramide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64994 CHEBI:15958 phosphatidyl-N-methylethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15958 UBERON:0012356 pedal acropodium region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012356 acropodial region of pes|toes set|all toes|toes|digits of foot|acropodial segment of pes|set of toes|acropodial forelimb segment|pedal acropodium region The segment of the pes that is distal to the metatarsal region and consists of the pedal digits (toes). CHEBI:64993 inositol phosphophytoceramide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64993 UBERON:0012355 manual acropodium region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012355 anterior acropodium segment of limb|anterior acropodium region|manual acropodium|acropodial segment of manus|acropodial hindlimb segment|fingers set|all fingers|set of digits of hand|acropodial region of manus|fingers including thumb|manual acropodium segment of limb|set of fingers|manual acropodium region|digits of hand|anterior acropodium|digiti manus The segment of the manus that is distal to the metacarpal region and consists of the manual digits (fingers). CHEBI:64992 inositol phosphomannosylinositol phosphophytoceramide(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64992 CHEBI:15955 discadenine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15955 CHEBI:64999 3,3'-bipyridine-2,2',5,5',6,6'-hexol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64999 CHEBI:64998 nicotine blue(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64998 CHEBI:15954 aldehydo-D-glucose 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15954 CHEBI:15957 stipitatic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15957 CHEBI:64997 mannosylinositol phosphorylceramide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64997 CHEBI:15956 biotin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15956 CHEBI:64996 EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64996 CHEBI:15951 3-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15951 CHEBI:15950 (S)-coclaurine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15950 CHEBI:15953 6-imino-5-oxocyclohexa-1,3-dienecarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15953 CHEBI:15952 dTDP-4-amino-4,6-dideoxy-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15952 GO:0106092 glial cell projection elongation involved in axon ensheathment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106092 The extension of a glial cell process or projection to wrap around an axon. GO:0106091 glial cell projection elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106091 The process of creating an elongation or projection from a glial cell. GO:0106090 positive regulation of cell adhesion involved in sprouting angiogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106090 Any process that activates or increases the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis. GO:0106096 response to ceramide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106096 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ceramide stimulus. CHEBI:74310 (9Z)-pentadecenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74310 GO:0106095 m7G(5')pppN diphosphatase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0106095 IntAct:EBI-15484673 m7G(5')pppN pyrophosphatase enzyme|m7G(5')pppN diphosphatase enzyme|DCS1 decapping scavenger complex|7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase enzyme|M(7)G(5')pppN pyrophosphatase enzyme A homodimeric protein complex that catalyzes the reaction: 7-methylguanosine-5'-triphospho-5'-pholynucleotide + H20 = 7-methylguanosine-5'-phosphate + polynucleotide. GO:0106094 nuclear membrane microtubule tethering complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0106094 A nuclear membrane protein complex which connects the nuclear outer and inner membranes together, and links thereby links the nuclear lumen to cytoplasmic microtubules. CHEBI:74312 (10Z,13Z,16Z,19Z,22Z,25Z)-octacosahexaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74312 CHEBI:74311 (10Z,13Z,16Z,19Z,22Z,25Z)-3-oxooctacosahexaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74311 GO:0106093 EDS1 disease-resistance complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0106093 IntAct:EBI-16422538|IntAct:EBI-16748728|IntAct:EBI-16423498|IntAct:EBI-16748636|IntAct:EBI-16423002|IntAct:EBI-16748699 EDS1-PAD4-SAG101 complex|EDS1-PAD4 complex|EDS1-SAG101 complex A plant complex involved in basal disease resistance and resistance (R) gene-mediated effector triggered immunity (ETI). Regulates accumulation of the hormone salicylic acid (SA) which is a necessary component of systemic immunity. Involved in responds to bacteria, viruses and oomycetes. GO:0106099 2-keto-3-deoxy-L-rhamnonate aldolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106099 EC:4.1.2.53|RHEA:25784 Catalysis of the reaction 2-dehydro-3-deoxy-L-rhamnonate = pyruvate + (S)-lactaldehyde. CHEBI:74324 L-glyceric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74324 GO:0106098 NAGS/NAGK complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0106098 IntAct:EBI-15101175 A protein complex that acts both as N-acetylglutamate synthase (NAGS) catalysing the production of N-Acetylglutamate from glutamate and acetyl-CoA, and as N-acetylglutamate kinase (NAGK) catalysing the reaction ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamyl 5-phosphate. GO:0106097 cellular response to ceramide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106097 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ceramide stimulus. CHEBI:74329 (13Z,16Z,19Z)-3-oxodocosatrienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74329 CHEBI:74328 (11Z,14Z,17Z)-icosatrienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74328 UBERON:0012344 holocrine gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012344 any exocrine gland whose secretion consists of its own disintegrated secretory cells along with its secretory product; holocrine secretions are produced in the cytoplasm of the cell and released by the rupture of the plasma membrane, which destroys the cell and results in the secretion of the product into the lumen. CHEBI:40910 azide anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_40910 CHEBI:15987 trithionate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15987 CHEBI:15989 L-methionine S-oxide residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15989 CHEBI:15984 N-(4-nitrophenyl)-3-oxovalidamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15984 CHEBI:15986 polynucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15986 CHEBI:15980 (R)-pantoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15980 CHEBI:15982 cob(I)alamin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15982 CHEBI:15981 heparan sulfate alpha-D-glucosaminide 3-sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15981 CHEBI:74320 (18Z,21Z,24Z,27Z,30Z,33Z)-3-oxohexatriacontahexaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74320 CHEBI:74322 4,8,12-trimethyltrideca 1,3,7,11-tetraene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74322 CHEBI:74335 1-acyl-2-(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-sn-glycero-3-phospho-D-myo-inositol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74335 CHEBI:74338 D-valine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74338 CHEBI:74337 D-asparagine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74337 CHEBI:74339 (6Z)-hexadecenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74339 GO:0047405 pyrimidine-5'-nucleotide nucleosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047405 MetaCyc:3.2.2.10-RXN|EC:3.2.2.10|RHEA:13425 Pyr5N activity|pyrimidine-5'-nucleotide phosphoribo(deoxyribo)hydrolase activity|pyrimidine nucleotide N-ribosidase activity Catalysis of the reaction: H2O + a pyrimidine 5'-nucleotide = ribose-5-phosphate + a pyrimidine. UBERON:0012332 broad ligament of uterus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012332 broad ligament|broad uterine ligament|ligamentum latum uteri A broad fold of peritoneum that extends from the side of the uterus to the wall of the pelvis. GO:0047404 glucuronosyl-disulfoglucosamine glucuronidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047404 MetaCyc:3.2.1.56-RXN|RHEA:15073|EC:3.2.1.56 glucuronosyl-disulphoglucosamine glucuronidase activity|3-D-glucuronsyl-2-N,6-disulfo-beta-D-glucosamine glucuronohydrolase activity|3-D-glucuronsyl-N2,6-disulfo-beta-D-glucosamine glucuronohydrolase activity Catalysis of the reaction: H2O + 3-D-glucuronosyl-N2-,6-disulfo-beta-D-glucosamine = glucuronate + N2,6-disulfo-D-glucosamine. UBERON:0012330 nasal-associated lymphoid tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012330 NALT|naso-pharyngeal lymphoid tissue The lymphocytic cell population present in the mucosa of the nasopharyngeal duct of some animals. GO:0047403 lacto-N-biosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047403 EC:3.2.1.140|RHEA:21568 oligosaccharide lacto-N-biosylhydrolase activity Catalysis of the reaction: H2O + beta-D-Gal-(1,3)-beta-D-GlcNAc-(1,3)-beta-D-Gal-(1,4)-D-Glc = beta-D-Gal-(1,4)-D-Glc + beta-D-Gal-(1,3)-D-GlcNAc. GO:0047402 protein-glucosylgalactosylhydroxylysine glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047402 EC:3.2.1.107|MetaCyc:3.2.1.107-RXN|RHEA:11068 2-O-alpha-D-glucopyranosyl-5-O-alpha-D-galactopyranosylhydroxy-L-lysine glucohydrolase activity|protein-alpha-D-glucosyl-1,2-beta-D-galactosyl-L-hydroxylysine glucohydrolase activity Catalysis of the reaction: H2O + protein alpha-D-glucosyl-1,2-beta-D-galactosyl-L-hydroxylysine = protein beta-D-galactosyl-L-hydroxylysine + beta-D-glucose. The enzyme specifically hydrolyzes glucose from alpha-D-glucosyl- (1->2)-beta-D-galactosyl disaccharide units that are linked to hydroxylysine residues of collagen and collagen-like proteins. GO:0047401 trithionate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047401 EC:3.12.1.1|MetaCyc:3.12.1.1-RXN|KEGG_REACTION:R01930|RHEA:21884 trithionate thiosulfohydrolase activity Catalysis of the reaction: H(2)O + trithionate = H(+) + sulfate + thiosulfate. GO:0047400 phosphonoacetate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047400 EC:3.11.1.2|KEGG_REACTION:R00318|RHEA:16749|MetaCyc:3.11.1.2-RXN phosphonoacetate phosphonohydrolase activity Catalysis of the reaction: H(2)O + phosphonoacetate = acetate + H(+) + phosphate. CHEBI:15977 cyclohex-2-enone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15977 UBERON:0012329 keratinized stratified squamous epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012329 epithelium stratificatum squamosum cornificatum Keratinized stratified squamous epithelium is a stratified squamous epithelium, the cells of which synthesize and accumulate keratin. CHEBI:15976 3-indoleglycolaldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15976 CHEBI:15979 1-benzyl-2-methyl-1,2,3,4-tetrahydroisoquinoline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15979 CHEBI:15978 sn-glycerol 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15978 GO:0047409 alkenylglycerophosphoethanolamine hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047409 MetaCyc:3.3.2.5-RXN|EC:3.3.2.5|RHEA:16905 1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine aldehydohydrolase activity Catalysis of the reaction: H2O + 1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine = sn-glycero-3-phosphoethanolamine + an aldehyde. GO:0047408 alkenylglycerophosphocholine hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047408 MetaCyc:3.3.2.2-RXN|EC:3.3.2.2|RHEA:22544 lysoplasmalogenase activity|1-(1-alkenyl)-sn-glycero-3-phosphocholine aldehydohydrolase activity Catalysis of the reaction: H2O + 1-(1-alkenyl)-sn-glycero-3-phosphocholine = L-1-glycero-3-phosphocholine + an aldehyde. CHEBI:15972 dTDP-4-amino-4,6-dideoxy-D-galactose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15972 CHEBI:15975 1D-5-O-methyl-myo-inositol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15975 GO:0047407 ADP-ribosyl-[dinitrogen reductase] hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047407 RHEA:14493|MetaCyc:3.2.2.24-RXN|EC:3.2.2.24 ADP-ribosyl-dinitrogen reductase hydrolase activity|azoferredoxin-activating enzymes|ADP-D-ribosyl-dinitrogen reductase ADP-ribosylhydrolase activity|azoferredoxin glycosidase activity|dinitrogenase reductase-activating glycohydrolase activity|ADP-ribosyl glycohydrolase activity|dinitrogenase reductase activating glycohydrolase activity Catalysis of the reaction: ADP-ribosyl-[dinitrogen reductase] = adenosine diphosphate ribose + [dinitrogen reductase]. GO:0047406 beta-aspartyl-N-acetylglucosaminidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047406 KEGG_REACTION:R01266|MetaCyc:3.2.2.11-RXN|EC:3.2.2.11|RHEA:12324 beta-aspartylacetylglucosaminidase activity|1-beta-aspartyl-N-acetyl-D-glucosaminylamine L-asparaginohydrolase activity Catalysis of the reaction: N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H(2)O = N-acetyl-D-glucosamine + L-asparagine. CHEBI:15971 L-histidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15971 CHEBI:15970 O-carbamoyl-L-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15970 CHEBI:74334 (10Z,13Z,16Z,19Z)-3-oxodocosatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74334 UBERON:0002916 central sulcus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002916 rolandic fissure|sulcus of Rolando|sulcus centralis (rolandi)|CS|central cerebral sulcus|central sulcus of Rolando|central fissure|sulcus centralis cerebri|fissure of Rolando|sulcus centralis The central sulcus is a fold in the cerebral cortex of brains in vertebrates. Also called the central fissure, it was originally called the fissure of Rolando or the Rolandic fissure, after Luigi Rolando. The central sulcus is a prominent landmark of the brain, separating the parietal lobe from the frontal lobe and the primary motor cortex from the primary somatosensory cortex. [WP,unvetted]. CHEBI:49388 bacterioruberin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49388 CHEBI:50372 (S)-rosmarinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50372 CHEBI:50371 (R)-rosmarinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50371 CHEBI:50370 parasympatholytic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50370 CHEBI:50375 dihydromethanophenazine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50375 CHEBI:50367 taxane diterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50367 CHEBI:50361 ketolactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50361 CHEBI:50360 (-)-1,2-campholide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50360 CHEBI:25399 cresol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25399 CHEBI:25392 naphthols biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25392 CHEBI:132623 nodakenetin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132623 CHEBI:50351 cyclopropanecarboxylate ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50351 CHEBI:50347 L-asparagine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50347 CHEBI:50349 D-asparagine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50349 CHEBI:50348 L-asparaginyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50348 CHEBI:50342 L-proline residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50342 CHEBI:50341 1-hydroxyethyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50341 CHEBI:50340 3-carbamimidamidopropyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50340 CHEBI:50336 4-hydroxybenzyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50336 CHEBI:50335 organic nitrogen anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50335 CHEBI:50334 pyridinium ion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50334 CHEBI:50339 4-aminobutyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50339 CHEBI:50338 1H-imidazol-4-ylmethyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50338 UBERON:0002956 granular layer of cerebellar cortex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002956 cerebellum granule cell layer|cerebellar granular layer|granular layer of cerebellum|stratum granulosum cerebelli|cerebellum granule layer|stratum granulosum corticis cerebelli|cerebellar granule cell layer|granule cell layer of cerebellar cortex|cerebellar granule layer The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer. CHEBI:50337 1H-indol-3-ylmethyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50337 CHEBI:25372 molybdopterin cofactor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25372 CHEBI:25371 molybdic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25371 CHEBI:25370 molybdenum molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25370 CHEBI:25375 monoamine molecular messenger biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25375 CHEBI:64900 [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl]acetyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64900 CHEBI:64908 (3E)-2-oxohex-3-enedioate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64908 CHEBI:64907 2-aminoicosane-1,3-diol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64907 CHEBI:64905 C20 sphinganine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64905 CHEBI:50331 3-amino-3-oxopropyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50331 BSPO:0005001 intersects_midsagittal_plane_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BSPO_0005001 BSPO:0005001 X intersects_median_plane of iff X crosses the midine plane of Y. CHEBI:50330 2-amino-2-oxoethyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50330 CHEBI:64909 poison biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64909 CHEBI:50325 proteinogenic amino-acid side-chain group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50325 CHEBI:50324 guanosine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50324 CHEBI:50323 2'-deoxyadenosine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50323 CHEBI:25389 monohydroxybenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25389 UBERON:0002949 tectospinal tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002949 Held's bundle|tectospinal pathway|tratto tettospinale@it|tractus tectospinalis|tectospinal tract of the medulla|tectospinal tract|tectospinal pathway A long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the superior colliculus of the midbrain towards target cells in the ventral spinal cord[GO]. CHEBI:25388 monohydroxybenzoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25388 CHEBI:50322 2'-deoxyguanosine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50322 UBERON:0002944 spinothalamic tract of medulla biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002944 spinothalamic tract|spinothalamic tract of the medulla|tractus spinothalamicus (myelencephali) Part of spinothalamic tract that is in the medulla CHEBI:50329 2-carboxyethyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50329 CHEBI:50327 selanylmethyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50327 CHEBI:50326 sulfanylmethyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50326 CHEBI:25381 monoalkyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25381 CHEBI:25380 acetylenic fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25380 CHEBI:25387 monohydroxyacetophenone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25387 CHEBI:25384 monocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25384 CHEBI:64911 antimitotic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64911 CHEBI:64910 C20 phytosphingosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64910 CHEBI:132610 phthalic acid monoester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132610 CHEBI:64915 antiplasmodial drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64915 CHEBI:64912 antimycobacterial drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64912 CHEBI:64919 EC 2.3.1.20 (diacylglycerol O-acyltransferase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64919 CHEBI:64918 C20 phytosphingosine 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64918 CHEBI:64917 C20 sphinganine 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64917 CHEBI:64916 inositol phosphoceramide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64916 CHEBI:50321 2'-deoxycytidine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50321 CHEBI:50320 nucleoside residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50320 CHEBI:50314 fluoronium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50314 CHEBI:50313 onium cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50313 CHEBI:25357 mitomycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25357 CHEBI:50312 onium compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50312 CHEBI:25355 mitochondrial respiratory-chain inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25355 CHEBI:50317 iodonium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50317 DDANAT:0000414 spore biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000414 spore cell Dormant cell protected by a tri-layer spore coat. The spore has an elliptical shape and is approximately 6-9 microns by 3 microns. CHEBI:50316 bromonium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50316 CHEBI:50315 chloronium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50315 CHEBI:25350 mevalonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_25350 DDANAT:0000410 pstAB cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000410 prestalk AB cell Cell that is undergoing differentiation to become a stalk cell. pstAB cells express both ecmA and ecmB either simultaneously or sequentially. During culmination pstA differentiate into pstAB cells. DDANAT:0000413 stalk cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000413 Cell of polyhedric shape filling the stalk tube. Stack cells are large (around 8 microns in diameter), highly vacuolated, and are surrounded by cell wall composed of cellulose. Stalk cells die upon terminal differentiation. Their role is to provide structural support for the fruiting body. CHEBI:50319 nucleotide residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50319 CHEBI:40992 N-acetyl-L-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_40992 CHEBI:25354 mineralocorticoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25354 CHEBI:49323 contraceptive drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49323 CHEBI:25351 mevalonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25351 CHEBI:49322 anthracycline antibiotic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49322 CHEBI:64921 3,4-dihydroxy-5-polyprenylbenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64921 CHEBI:64926 serine protease inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64926 CHEBI:64925 4beta-methylzymosterol-4alpha-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64925 CHEBI:64928 2-oxohex-3-enedioate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64928 CHEBI:64927 2-oxohex-3-enedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64927 DDANAT:0000408 pstA cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000408 prestalk A cell|pstAO cell Cell that is undergoing differentiation to become a stalk cell. pstA cells express the ecmA marker from a promoter region that is proximal to the ATG (ecmAO promoter). They are located at the anterior-most region of the slug. During culmination pstA cells differentiate into pstAB cells. UBERON:0002926 gustatory epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002926 A sensory epithelium that is part of a gustatory system. CHEBI:50303 terpentedienyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50303 CHEBI:49314 germacrene B biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49314 CHEBI:50302 terpentetriene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50302 UBERON:0002925 trigeminal nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002925 nucleus mesencephalicus nervi trigemini|trigeminal nuclear complex nucleus|trigeminal V nucleus|nucleus tractus mesencephali nervi trigeminalis|trigeminal nucleus|nucleus of trigeminal nuclear complex|nucleus mesencephalicus trigeminalis A nucleus of brain that is part of a trigeminal nuclear complex. UBERON:0002928 dentate gyrus polymorphic layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002928 polymorph layer of the dentate gyrus|CA4 A cellular layer of the dentate gyrus enclosed by the granule cell layer. A number of cell types are located in the polymorphic layer but the most prominent is the mossy cell. CHEBI:25367 molecule biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25367 CHEBI:50300 thymidine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50300 CHEBI:49318 piperidine antibiotic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49318 CHEBI:50307 furonaphthodioxole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50307 UBERON:0002921 longitudinal fissure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002921 longitudinal fissure of the cerebrum|sagittal fissure|hemispheric sulcus|longitudinal fissure of hemisphere|fissura longitudinalis magna|fissura longitudinalis cerebri|longitudinal sulcus|fissura longitudinalis cerebrales|longitudinal cerebral fissure|LF|fissura interhemispherica|medial longitudinal fissure|interhemispheric fissure The deep groove which separates the two hemispheres of the vertebrate brain. The falx cerebri, a dural brain covering, lies within the medial longitudinal fissure. [WP,unvetted]. CHEBI:50306 adenosine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50306 DDANAT:0000403 aggregate cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000403 Differentiating cell composing the aggregate that has acquired adhesive properties. DDANAT:0000406 prestalk cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000406 pst cell|anterior cell Cell that is undergoing differentiation to become a stalk cell and characterized by the ability to update vital dyes. Represents about one-quarter of the cells. During development, prestalk cells are located in the anterior portion of the organism. CHEBI:50305 podophyllotoxin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50305 DDANAT:0000405 prespore cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000405 psp cell Cell that is undergoing differentiation to become a spore. Characterized by the presence of prespore vesicles (PV). CHEBI:49319 carbocyclic antibiotic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49319 DDANAT:0000402 chemotactic amoeboid cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000402 amoebae Starved cell that secretes and responds to chemoattractants (cAMP). DDANAT:0000401 cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/DDANAT_0000401 Anatomical structure that has as its parts a maximally connected cell compartment surrounded by a plasma membrane. CHEBI:50308 cytidine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50308 CHEBI:49310 7-methylxanthosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49310 CHEBI:49311 alpha-humulene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49311 CHEBI:25362 elemental molecule biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25362 CHEBI:64933 melanin synthesis inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64933 CHEBI:64931 lysophosphatidyl-1D-myo-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64931 CHEBI:64930 1-acyl-sn-glycero-3-phospho-1D-myo-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64930 CHEBI:64937 3-heptaprenyl-sn-glycero-1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64937 CHEBI:64936 N(pros)-phospho-L-histidine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64936 CHEBI:64939 3,4-dihydro-4-hydroxyphenylpyruvic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64939 CHEBI:64938 N(pros)-phospho-L-histidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64938 GO:0047375 N-acetylgalactosaminoglycan deacetylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047375 EC:3.1.1.58|MetaCyc:3.1.1.58-RXN Vi-polysaccharide deacetylase activity|N-acetyl-D-galactosaminoglycan acetylhydrolase activity|polysaccharide deacetylase activity|N-acetyl galactosaminoglycan deacetylase activity Catalysis of the reaction: H2O + N-acetyl-D-galactosaminoglycan = acetate + D-galactosaminoglycan. GO:0072331 signal transduction by p53 class mediator biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072331 An intracellular signaling process that is induced by the cell cycle regulator phosphoprotein p53 or an equivalent protein. GO:0072330 monocarboxylic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072330 monocarboxylic acid biosynthesis|monocarboxylic acid anabolism|monocarboxylic acid synthesis|monocarboxylic acid formation The chemical reactions and pathways resulting in the formation of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group. GO:0047374 methylumbelliferyl-acetate deacetylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047374 EC:3.1.1.56|RHEA:12208|KEGG_REACTION:R04141|MetaCyc:3.1.1.56-RXN esterase D activity|4-methylumbelliferyl-acetate acylhydrolase activity Catalysis of the reaction: 4-methylumbelliferyl acetate + H(2)O = 4-methylumbelliferone + acetate + H(+). GO:0047373 acetoxybutynylbithiophene deacetylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047373 RHEA:11548|EC:3.1.1.54|KEGG_REACTION:R04490|MetaCyc:3.1.1.54-RXN 5-(4-acetoxy-1-butynyl)-2,2'-bithiophene:acetate esterase activity|5-(4-acetoxybut-1-ynyl)-2,2'-bithiophene O-acetylhydrolase activity|acetoxybutynylbithiophene esterase activity Catalysis of the reaction: 5-(4-acetoxybut-1-ynyl)-2,2'-bithiophene + H(2)O = 5-(4-hydroxy-but-1-ynyl)-2,2'-bithiophene + acetate + H(+). GO:0047372 acylglycerol lipase activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0047372 EC:3.1.1.23|RHEA:34019|Reactome:R-HSA-426032|Reactome:R-HSA-1482543|Reactome:R-HSA-192422|MetaCyc:3.1.1.23-RXN|Reactome:R-HSA-192430|Reactome:R-HSA-192475|Reactome:R-HSA-163595|Reactome:R-HSA-5694462|Reactome:R-HSA-426043|Reactome:R-HSA-192434|Reactome:R-HSA-192425 monoglyceride lipase activity|fatty acyl monoester lipase activity|monoglyceridase activity|monoacylglycerolipase activity|glycerol-ester acylhydrolase activity|monoglyceride hydrolase activity|monoacylglycerol hydrolase activity|monoglyceridyllipase activity|monoacylglycerol lipase activity Catalysis of the reaction: H2O + acylglycerol = a fatty acid + glycerol. GO:0047371 butyrate-acetoacetate CoA-transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047371 MetaCyc:2.8.3.9-RXN|EC:2.8.3.9|KEGG_REACTION:R01365|RHEA:12961 butyryl coenzyme A-acetoacetate coenzyme A-transferase activity|butyryl-CoA-acetoacetate CoA-transferase activity|butanoyl-CoA:acetoacetate CoA-transferase activity Catalysis of the reaction: acetoacetate + butanoyl-CoA = acetoacetyl-CoA + butanoate. GO:0047370 succinate-citramalate CoA-transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047370 MetaCyc:2.8.3.7-RXN|RHEA:23528 succinyl coenzyme A-citramalyl coenzyme A transferase activity|succinyl-CoA:citramalate CoA-transferase activity|citramalate coenzyme A-transferase activity|itaconate CoA-transferase activity Catalysis of the reaction: S-citramalate + succinyl-CoA = citramalyl-CoA + succinate. CL:0002427 resting double-positive thymocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002427 T.DP.sm.Th A double-positive, alpha-beta thymocyte that is small and not proliferating. CL:0002429 CD69-positive double-positive thymocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002429 T.DP69+.Th A double-positive thymocyte that is CD69-positive and has begun positive selection. CL:0002428 double-positive blast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002428 activated double-positive thymocyte|T.DPb.Th A double-positive thymocyte that is large (i.e. has a high forward scatter signal in flow cytometry) and is actively proliferating. CHEBI:142058 F2-isoprostane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_142058 GO:0047379 ADP-dependent short-chain-acyl-CoA hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047379 EC:3.1.2.18|MetaCyc:3.1.2.18-RXN ADP-dependent propionyl-CoA hydrolase activity|ADP-dependent short-chain acyl-CoA thioesterase activity|ADP-dependent propionyl-CoA thioesterase activity|ADP-dependent short-chain acyl coenzyme A hydrolase activity|ADP-dependent-short-chain-acyl-CoA hydrolase activity|ADP-dependent propionyl coenzyme A hydrolase activity|ADP-dependent short-chain acyl-CoA hydrolase activity Catalysis of the reaction: H2O + a short-chain acyl-CoA = a short-chain carboxylate + CoA. CHEBI:142057 3-hydroxy-L-aspartic acid residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_142057 GO:0047378 acetylalkylglycerol acetylhydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047378 EC:3.1.1.71|RHEA:11552|KEGG_REACTION:R04043|MetaCyc:3.1.1.71-RXN 2-acetyl-1-alkyl-sn-glycerol acetylhydrolase activity|alkylacetylglycerol acetylhydrolase activity Catalysis of the reaction: 2-acetyl-1-alkyl-sn-glycerol + H(2)O = 1-alkyl-sn-glycerol + acetate + H(+). GO:0047377 5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene deacetylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047377 EC:3.1.1.66|KEGG_REACTION:R04525|RHEA:16313|MetaCyc:3.1.1.66-RXN 3,4-diacetoxybutinylbithiophene:4-acetate esterase activity|5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene acetylhydrolase activity|diacetoxybutynylbithiophene acetate esterase activity Catalysis of the reaction: 5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene + H(2)O = 5-(3-hydroxy-4-acetoxybut-1-ynyl)-2,2'-bithiophene + acetate + H(+). GO:0047376 all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047376 Reactome:R-HSA-2404140|RHEA:13933|Reactome:R-HSA-2429643|KEGG_REACTION:R02368|MetaCyc:3.1.1.64-RXN|EC:3.1.1.- all-trans-retinyl-palmitate acylhydrolase activity|retinyl-palmitate palmitohydrolase activity|all-trans-retinyl-palmitate hydrolase activity Catalysis of the reaction: all-trans-retinyl palmitate + H2O = all-trans-retinol + H+ + palmitate. CHEBI:142054 3-hydroxyaspartic acid residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_142054 CL:0002421 nucleated reticulocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002421 A reticulocyte that retains the nucleus and other organelles. Found in birds, fish, amphibians and reptiles. CL:0002420 immature T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002420 immature T-cell A T cell that has not completed T cell selection. CL:0002423 DN2a thymocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002423 A DN2 thymocyte that is Kit-hi. CL:0002422 enucleated reticulocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002422 A reticulocyte lacking a nucleus and showing a basophilic reticulum under vital staining due to the presence of ribosomes. CL:0002425 early T lineage precursor biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002425 ETP|preT.ETP.Th A pro-T cell that is lin-negative, CD25-negative, CD127-negative, CD44-positive and kit-positive. CL:0002424 DN2b thymocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002424 A DN2 thymocyte that is Kit-low. GO:0072339 cellular lactam biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072339 cellular lactam biosynthesis|cellular lactam anabolism|cellular lactam synthesis|cellular lactam formation The chemical reactions and pathways resulting in the formation of lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring. GO:0072338 cellular lactam metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072338 cellular lactam metabolism The chemical reactions and pathways involving lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring. GO:0072337 modified amino acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072337 amino acid derivative transport The directed movement of modified amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0072336 negative regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072336 negative regulation of canonical Wnt-activated signaling pathway involved in neural crest cell differentiation|negative regulation of canonical Wnt receptor signaling pathway involved in neural crest cell differentiation|negative regulation of Wnt receptor signaling pathway through beta-catenin involved in neural crest cell differentiation|negative regulation of canonical Wnt receptor signalling pathway involved in neural crest cell differentiation Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin involved in neural crest cell differentiation. The Wnt signaling pathway is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. GO:0072335 regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072335 regulation of Wnt receptor signaling pathway through beta-catenin involved in neural crest cell differentiation|regulation of canonical Wnt receptor signalling pathway involved in neural crest cell differentiation|regulation of canonical Wnt receptor signaling pathway involved in neural crest cell differentiation|regulation of canonical Wnt-activated signaling pathway involved in neural crest cell differentiation Any process that modulates the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin involved in neural crest cell differentiation. The Wnt signaling pathway is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. GO:0072334 UDP-galactose transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072334 UDP-galactose transport|UDP-galactose membrane transport The process in which UDP-galactose is transported across a membrane. GO:0072333 obsolete anoikis by p53 class mediator biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072333 anoikis by p53 class mediator|anoikis by signal transduction by p53 class mediator|signal transduction by p53 class mediator resulting in induction of anoikis OBSOLETE. A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, that results in the induction of anoikis. GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072332 intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|signal transduction by p53 class mediator resulting in induction of apoptosis A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, and ends when the execution phase of apoptosis is triggered. GO:0047386 fructose-2,6-bisphosphate 6-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047386 MetaCyc:3.1.3.54-RXN|EC:3.1.3.54|KEGG_REACTION:R02730|RHEA:13333 fructose-2,6-bisphosphate 6-phosphohydrolase activity|beta-D-fructose-2,6-bisphosphate 6-phosphohydrolase activity|D-fructose-2,6-bisphosphate 6-phosphohydrolase activity|fructose 2,6-bisphosphate-6-phosphohydrolase activity Catalysis of the reaction: beta-D-fructose 2,6-bisphosphate + H(2)O = beta-D-fructofuranose 2-phosphate + phosphate. GO:0072320 volume-sensitive chloride channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0072320 swell-activated chloride channel Enables the transmembrane transfer of a chloride ion by a volume-sensitive channel. A volume-sensitive channel is a channel that responds to changes in the volume of a cell. GO:0047385 [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047385 MetaCyc:3.1.3.52-RXN|EC:3.1.3.52 branched-chain alpha-keto acid dehydrogenase phosphatase|branched-chain oxo-acid dehydrogenase phosphatase activity|3-methyl-2-oxobutanoate dehydrogenase (lipoamide)-phosphate phosphohydrolase activity|3-methyl-2-oxobutanoate dehydrogenase (lipoamide)-phosphatase activity|branched-chain 2-keto acid dehydrogenase phosphatase activity Catalysis of the reaction: H2O + [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)] phosphate = phosphate + [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]. GO:0047384 [hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047384 MetaCyc:3.1.3.47-RXN|EC:3.1.3.47 hydroxymethylglutaryl-CoA reductase (NADPH)-phosphate phosphohydrolase activity|hydroxymethylglutaryl-CoA reductase (NADPH)-phosphatase activity|reductase phosphatase activity Catalysis of the reaction: H2O + [hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate = phosphate + [hydroxymethylglutaryl-CoA reductase (NADPH)]. GO:0047383 guanidinodeoxy-scyllo-inositol-4-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047383 MetaCyc:3.1.3.40-RXN|EC:3.1.3.40|RHEA:15777|KEGG_REACTION:R03496 1-guanidino-1-deoxy-scyllo-inositol-4-phosphate 4-phosphohydrolase activity|1-guanidino-scyllo-inositol 4-phosphatase activity|1-guanidino-1-deoxy-scyllo-inositol-4-P phosphohydrolase activity Catalysis of the reaction: 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + H(2)O = 1-guanidino-1-deoxy-scyllo-inositol + phosphate. GO:0047382 methylphosphothioglycerate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047382 MetaCyc:3.1.3.14-RXN|RHEA:16081|EC:3.1.3.14|KEGG_REACTION:R04317 S-methyl-3-phospho-1-thio-D-glycerate phosphohydrolase activity|methylthiophosphoglycerate phosphatase activity Catalysis of the reaction: S-methyl-3-phospho-1-thio-D-glycerate + H(2)O = S-methyl-1-thio-D-glycerate + phosphate. GO:0047381 dodecanoyl-[acyl-carrier-protein] hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047381 MetaCyc:3.1.2.21-RXN|RHEA:30119|EC:3.1.2.21 dodecanoyl-ACP hydrolase activity|lauryl-acyl-carrier-protein hydrolase activity|dodecyl-acyl-carrier protein hydrolase|dodecyl-[acyl-carrier protein] hydrolase activity|dodecanoyl-acyl-carrier-protein hydrolase activity|lauryl-[acyl-carrier protein] hydrolase activity|lauroyl-[acyl-carrier-protein] hydrolase activity|lauryl-acyl-carrier protein hydrolase activity|dodecanoyl-[acyl-carrier protein] hydrolase activity|lauroyl-ACP hydrolase activity Catalysis of the reaction: H2O + dodecanoyl-[acyl-carrier protein] = dodecanoate + [acyl-carrier protein]. GO:0047380 ADP-dependent medium-chain-acyl-CoA hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047380 EC:3.1.2.19|MetaCyc:3.1.2.19-RXN ADP-dependent medium-chain hydrolase activity|ADP-dependent-medium-chain-acyl-CoA hydrolase activity|ADP-dependent medium-chain acyl-CoA hydrolase activity|ADP-dependent myristoyl-CoA thioesterase activity|ADP-dependent medium-chain acyl-thioester hydrolase activity|ADP-dependent medium-chain acyl coenzyme A hydrolase activity Catalysis of the reaction: H2O + a medium-chain acyl-CoA = a medium-chain carboxylate + CoA. Requires ADP. CL:0002437 mature CD8 single-positive thymocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002437 T.8SP24-.Th A mature CD8-positive, CD4-negative alpha-beta T cell found in the thymus that is CD24-low and has high expression of the T cell receptor. GO:0047389 glycerophosphocholine phosphodiesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047389 EC:3.1.4.2|RHEA:16061|Reactome:R-HSA-6814132|MetaCyc:3.1.4.2-RXN glycerophosphohydrolase activity|glycerophosphinicocholine diesterase activity|sn-glycero-3-phosphorylcholine diesterase activity|sn-glycero-3-phosphocholine glycerophosphohydrolase activity|glycerolphosphorylcholine phosphodiesterase activity|glycerylphosphorylcholinediesterase activity Catalysis of the reaction: H2O + L-1-glycero-3-phosphocholine = glycerol-3-phosphate + choline. GO:0047388 [glutamine synthetase]-adenylyl-L-tyrosine phosphorylase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047388 KEGG_REACTION:R03474|EC:2.7.7.89|MetaCyc:3.1.4.15-RXN|RHEA:43716 adenylyl-glutamate-ammonia ligase hydrolase activity|adenylyl(glutamine synthetase) hydrolase activity|adenylyl-glutamine-synthetasehydrolase activity|adenylyl-[glutamate-ammonia ligase] hydrolase activity|adenylyl-L-glutamate:ammonia ligase (ADP-forming) adenylylhydrolase activity Catalysis of the reaction: adenylyl-[L-glutamate:ammonia ligase (ADP-forming)] + H2O = AMP + [L-glutamate:ammonia ligase (ADP-forming)]. GO:0047387 serine-ethanolaminephosphate phosphodiesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047387 RHEA:17113|MetaCyc:3.1.4.13-RXN|KEGG_REACTION:R02817|EC:3.1.4.13 SEP diesterase activity|serine-phosphoethanolamine ethanolaminephosphohydrolase activity|serine ethanolamine phosphodiester phosphodiesterase activity Catalysis of the reaction: H(2)O + serine phosphoethanolamine = H(+) + phosphoethanolamine + serine. CL:0002430 CD4-intermediate, CD8-positive double-positive thymocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002430 T.4int8+.Th A double-positive thymocyte that is undergoing positive selection, has high expression of the alpha-beta T cell receptor, is CD69-positive, and is in the process of down regulating the CD4 co-receptor. CL:0002432 CD24-positive, CD4 single-positive thymocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002432 T.4SP24int.Th|CD24-positive, CD4 single-positive semimature thymocyte A CD4-positive, CD8-negative thymocyte that is CD24-positive and expresses high levels of the alpha-beta T cell receptor. CL:0002431 CD4-positive, CD8-intermediate double-positive thymocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002431 T.4int8+.th A double-positive thymocyte that is undergoing positive selection, has high expression of the alpha-beta T cell receptor, is CD69-positive, and is in the process of down regulating the CD8 co-receptor. CL:0002434 CD24-positive, CD8 single-positive thymocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002434 T.8SP24int.Th|CD24-positive, CD8 single-positive semimature thymocyte A CD8-positive, CD4-negative thymocyte that is CD24-positive and expresses high levels of the alpha-beta T cell receptor. SO:0001914 rDNA_replication_fork_barrier biolink:SequenceFeature go-plus http://purl.obolibrary.org/obo/SO_0001914 RTS1 element|DNA spacer replication fork barrier|RTS1 barrier|RFB|rDNA replication fork barrier A DNA motif that is found in eukaryotic rDNA repeats, and is a site of replication fork pausing. CL:0002433 CD69-positive, CD4-positive single-positive thymocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002433 intermediate CD4-single-positive|T.4SP69+.Th A CD4-positive, CD8-negative thymocyte that expresses high levels of the alpha-beta T cell receptor and is CD69-positive. CL:0002436 mature CD4 single-positive thymocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002436 T.4SP24-.Th A mature CD4-positive, CD8-negative alpha-beta T cell found in the thymus that is CD24-low and has high expression of the T cell receptor. CL:0002435 CD69-positive, CD8-positive single-positive thymocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002435 intermediate CD8-single-positive|T.8SP69+.Th A CD8-positive, CD4-negative thymocyte that expresses high levels of the alpha-beta T cell receptor and is CD69-positive. GO:0072329 monocarboxylic acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072329 The chemical reactions and pathways resulting in the breakdown of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group. GO:0072328 alkene binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0072328 Interacting selectively and non-covalently with an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n. GO:0072327 vulval cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072327 The process in which a cell becomes capable of differentiating autonomously into a nematode vulval cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes. GO:0072326 vulval cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072326 The process in which a cell becomes capable of differentiating autonomously into a nematode vulval cell regardless of its environment; upon determination, the cell fate cannot be reversed. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes. GO:0072325 vulval cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072325 The process in which the cellular identity of nematode vulval cells is acquired and determined. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes. GO:0072324 ascus epiplasm biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0072324 Ascus cytoplasm that is not packaged into ascospores. GO:0072323 chaperone-mediated protein transport across periplasmic space biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072323 The directed movement of proteins from the plasma membrane across the periplasmic space to the outer membrane, mediated by chaperone molecules that bind to the transported proteins. This process has been observed in Gram-negative bacteria. GO:0072322 protein transport across periplasmic space biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072322 The directed movement of proteins from the plasma membrane across the periplasmic space to the outer membrane or cell wall. GO:0072321 chaperone-mediated protein transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072321 The directed movement of proteins into, out of or within a cell, or between cells, mediated by chaperone molecules that bind to the transported proteins. GO:0047397 dolichylphosphate-glucose phosphodiesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047397 EC:3.1.4.48|RHEA:13857|MetaCyc:3.1.4.48-RXN Dol-P-Glc phosphodiesterase activity|dolichyl-beta-D-glucosyl-phosphate dolichylphosphohydrolase activity|dolichol phosphoglucose phosphodiesterase activity|dolichyl-phosphate-glucose phosphodiesterase activity Catalysis of the reaction: dolichyl beta-D-glucosyl phosphate + H2O = dolichol-phosphate + beta-D-glucose. GO:0072353 cellular age-dependent response to reactive oxygen species biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072353 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of reactive oxygen species, where the change varies according to the age of the cell or organism. GO:0047396 glycosylphosphatidylinositol diacylglycerol-lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047396 EC:4.6.1.14|RHEA:14333|MetaCyc:3.1.4.47-RXN 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol diacyl-sn-glycerol-lyase [6-(alpha-D-glucosaminyl)-1D-myo-inositol 1,2-cyclic phosphate-forming]|GPI-PLC activity|glycosyl inositol phospholipid anchor-hydrolyzing enzyme activity|(glycosyl)phosphatidylinositol-specific phospholipase C activity|GPI-specific phospholipase C activity|VSG-lipase activity|6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol diacylglycerol-lyase (1,2-cyclic-phosphate-forming) activity|variant-surface-glycoprotein phospholipase C activity|glycosylphosphatidylinositol-specific phospholipase C activity|glycosylphosphatidylinositol-phospholipase C activity Catalysis of the reaction: 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol = 1,2-diacyl-sn-glycerol + 6-(alpha-D-glucosaminyl)-1D-myo-inositol 1,2-cyclic phosphate. GO:0072352 tricarboxylic acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072352 tricarboxylic acid catabolism|tricarboxylate catabolic process|tricarboxylic acid degradation|tricarboxylate catabolism|tricarboxylic acid breakdown The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing three carboxyl (-COOH) groups. GO:0047395 glycerophosphoinositol glycerophosphodiesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047395 Reactome:R-HSA-6813740|EC:3.1.4.44|RHEA:16501|KEGG_REACTION:R01193|MetaCyc:3.1.4.44-RXN sn-glycero(3)phosphoinositol glycerophosphohydrolase activity|1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase activity|sn-glycero-3-phospho-1-inositol glycerophosphohydrolase activity Catalysis of the reaction: 1-(sn-glycero-3-phospho)-1D-myo-inositol + H(2)O = sn-glycerol 3-phosphate + myo-inositol + H(+). GO:0072351 tricarboxylic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072351 tricarboxylic acid synthesis|tricarboxylic acid formation|tricarboxylic acid biosynthesis|tricarboxylate biosynthetic process|tricarboxylate biosynthesis|tricarboxylic acid anabolism The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing three carboxyl (-COOH) groups. GO:0072350 tricarboxylic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072350 tricarboxylic acid metabolism The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing three carboxyl (COOH) groups or anions (COO-). GO:0047394 glycerophosphoinositol inositolphosphodiesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047394 EC:3.1.4.43|RHEA:14033|MetaCyc:3.1.4.43-RXN 1-D-myo-inositol-1,2-cyclic-phosphate 2-inositolphosphohydrolase activity|1-(sn-glycero-3-phospho)-1D-myo-inositol inositolphosphohydrolase activity|D-myo-inositol 1:2-cyclic phosphate 2-phosphohydrolase activity|1,2-cyclic-inositol-phosphate phosphodiesterase activity|D-inositol 1,2-cyclic phosphate 2-phosphohydrolase activity|inositol-1,2-cyclic-phosphate 2-inositolphosphohydrolase activity|D-myo-inositol 1,2-cyclic phosphate 2-phosphohydrolase activity Catalysis of the reaction: H2O + 1-(sn-glycero-3-phospho)-1D-myoinositol = 1D-myo-inositol 1-phosphate + glycerol. GO:0047393 glycerol-1,2-cyclic-phosphate 2-phosphodiesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047393 KEGG_REACTION:R02648|EC:3.1.4.42|RHEA:16493|MetaCyc:3.1.4.42-RXN rac-glycerol 1:2-cyclic phosphate 2-phosphodiesterase activity|rac-glycerol-1,2-cyclic-phosphate 2-glycerophosphohydrolase activity Catalysis of the reaction: glycerol 1,2-cyclic phosphate + H(2)O = glycerol 1-phosphate + H(+). GO:0047392 CMP-N-acylneuraminate phosphodiesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047392 EC:3.1.4.40|RHEA:20185|MetaCyc:3.1.4.40-RXN CMP-sialate hydrolase activity|cytidine monophosphate-N-acetylneuraminic acid hydrolase activity|cytidine monophosphosialate hydrolase activity|CMP-N-acylneuraminate N-acylneuraminohydrolase activity|cytidine monophosphosialic hydrolase activity|CMP-sialic acid hydrolase activity|CMP-N-acylneuraminic acid hydrolase activity|CMP-N-acetylneuraminate hydrolase activity Catalysis of the reaction: H2O + CMP-N-acylneuraminate = N-acylneuraminate + CMP. GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047391 RHEA:15965|MetaCyc:3.1.4.39-RXN|EC:3.1.4.39 lysophospholipase D activity|1-alkyl-sn-glycero-3-phosphoethanolamine ethanolaminehydrolase activity Catalysis of the reaction: H2O + 1-alkyl-sn-glycero-3-phosphoethanolamine = ethanolamine + 1-alkyl-sn-glycerol 3-phosphate. GO:0047390 glycerophosphocholine cholinephosphodiesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047390 RHEA:19545|KEGG_REACTION:R02591|MetaCyc:3.1.4.38-RXN|Reactome:R-HSA-6814797|EC:3.1.4.38 sn-glycero-3-phosphocholine cholinephosphohydrolase activity|L-3-glycerylphosphinicocholine cholinephosphohydrolase activity Catalysis of the reaction: sn-glycero-3-phosphocholine + H(2)O = choline phosphate + glycerol + H(+). CL:0002405 gamma-delta thymocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002405 gammadelta thymocyte|gd thymocyte A post-natal thymocyte expressing components of the gamma-delta T cell receptor. This cell type is always double-negative (i.e. CD4-negative, CD8-negative). CL:0002404 fetal thymocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002404 A thymocyte found in the fetal thymus. GO:0047399 glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047399 EC:3.1.4.51|RHEA:18045|MetaCyc:3.1.4.51-RXN alpha-glucose-1-phosphate phosphodiesterase activity|6-(D-glucose-1-phospho)-D-mannosylglycoprotein glucose-1-phosphohydrolase activity Catalysis of the reaction: H2O + 6-(D-glucose-1-phospho)-D-mannosylglycoprotein = D-mannosylglycoprotein + D-glucose-alpha-1-phosphate. GO:0047398 dolichylphosphate-mannose phosphodiesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047398 EC:3.1.4.49|RHEA:12989|MetaCyc:3.1.4.49-RXN mannosylphosphodolichol phosphodiesterase activity|dolichyl-beta-D-mannosyl-phosphate dolichylphosphohydrolase activity Catalysis of the reaction: dolichyl beta-D-mannosyl phosphate + H2O = dolichol-phosphate + mannose. CL:0002401 mature dendritic epithelial T cell precursor biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002401 mature DEC precursor|mature DETC precursor A thymocyte that has a T cell receptor consisting of a gamma chain that has as part a Vgamma3 segment, and a delta chain. This cell type is CD4-negative, CD8-negative and CD24-negative. This cell-type is found in the fetal thymus with highest numbers occurring at E17-E18. CL:0002400 Fraction B/C precursor B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002400 A precursor B cell that is AA4-positive, IgM-negative, CD19-positive, CD43-positive and HSA-positive. CL:0002402 Peyer's patch B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002402 Peyers patch B cell A resting mature B cell within the Peyer's patch that is CD19-positive, B220-positive, IgM-positive, AA4-negative, CD23-positive, CD43-negative, and CD5-negative. GO:0072359 circulatory system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072359 cardiovascular system development The process whose specific outcome is the progression of the circulatory system over time, from its formation to the mature structure. The circulatory system is the organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis. GO:0072358 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072358 GO:0072357 PTW/PP1 phosphatase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0072357 A protein serine/threonine phosphatase complex that contains a catalytic subunit (PPP1CA, PPP1CB or PPP1CC) and the regulatory subunits PPP1R10 (PNUTS), TOX4 and WDR82, and plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. GO:0072356 chromosome passenger complex localization to kinetochore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072356 CPC localization to kinetochore|chromosome passenger complex localisation to kinetochore|chromosomal passenger complex localization to kinetochore|CPC complex localization to kinetochore A cellular protein complex localization that acts on a chromosome passenger complex; as a result, the complex is transported to, or maintained in, a specific location at the kinetochore. A chromosome passenger complex is a protein complex that contains the BIR-domain-containing protein Survivin, Aurora B kinase, INCENP and Borealin, and coordinates various events based on its location to different structures during the course of mitosis. GO:0072355 histone H3-T3 phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072355 The modification of histone H3 by the addition of an phosphate group to a threonine residue at position 3 of the histone. GO:0072354 histone kinase activity (H3-T3 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0072354 histone-threonine kinase activity (H3-T3 specific)|histone threonine kinase activity (H3-T3 specific) Catalysis of the transfer of a phosphate group to the threonine-3 residue of the N-terminal tail of histone H3. GO:0072342 response to anion stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072342 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of anion stress, an increase or decrease in the concentration of negatively charged ions in the environment. GO:0106100 beta-pinacene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106100 Catalysis of the cyclization of geranylgeranyl pyrophosphate (GGPP) to yield the monocyclic diterpene beta-pinacene. GO:0072341 modified amino acid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0072341 amino acid derivative binding Interacting selectively and non-covalently with a modified amino acid. GO:0072340 cellular lactam catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072340 cellular lactam degradation|cellular lactam breakdown|cellular lactam catabolism The chemical reactions and pathways resulting in the breakdown of lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring. GO:0106104 regulation of glutamate receptor clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106104 Any process that modulates the frequency, rate or extent of glutamate receptor clustering. GO:0106103 COPII vesicles tethering complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0106103 IntAct:EBI-14061261 GRASP65-GM130 complex|Bug1-Grh1 complex A protein complex that resides in the cis-golgi membrane and plays a role in the tethering of COPII vesicles, through an interaction with vesicle tethering proteins (p115 in H. Sapiens and Uso1 S. cerevisiae), granting the cis-Golgi and endoplasmic reticulum to Golgi vesicle-mediated transport. It is composed by GRASP65 and GM130 protein in H. sapiens and by Bug1 and Grh1 proteins in S. cerevisiae. GO:0106101 ER-dependent peroxisome localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106101 A process in which a protein is transported to, or maintained at, a location in a peroxisome via the endoplasmic reticulum. GO:0106108 negative regulation of (R)-mevalonic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106108 Any process that stops, prevents or reduces the frequency, rate or extent of (R)-mevalonic acid biosynthetic process. GO:0106107 regulation of (R)-mevalonic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106107 Any process that modulates the frequency, rate or extent of (R)-mevalonic acid biosynthetic process. GO:0106106 cold-induced thermogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106106 CIT The process by which heat is generated by increasing metabolism in response to cold ambient temperatures in order to maintain a stable core body temperature. CL:0002418 hemangioblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002418 A pluripotent cell in the yolk sac that can give rise to mesenchymal cells including erythrocytes and endothelial cells. GO:0106105 Ala-tRNA(Thr) hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106105 L-alanyl-tRNA(Thr) deacylase Catalysis of the hydrolysis of misacylated ala-tRNA(thr). CL:0002417 primitive erythroid lineage cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002417 An immature or mature cell of the first erythroid lineage to arise during embryonic development. CL:0002419 mature T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002419 mature T-cell|CD3epsilon T cell|CD3e-positive T cell A T cell that expresses a T cell receptor complex and has completed T cell selection. GO:0106109 positive regulation of (R)-mevalonic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106109 Any process that activates or increases the frequency, rate or extent of (R)-mevalonic acid biosynthetic process. CL:0002410 pancreatic stellate cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002410 PaSC|pancreas stellate cell A cell that is found in the periacinar space of the exocrine pancreas and in perivascular and periductal regions of the pancreas, and has long cytoplasmic processes that encircle the base of the acinus. Expresses several intermediate filament proteins including vimentin and nestin. Shares many of the characteristics of hepatatic stellate cells, but not stellate cells of the central nervous system. Upon activation, this cell type undergoes morphological and gene expression changes that make the cell suggestive of being a type of myofibroblast. GO:0072349 modified amino acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0072349 modified amino acid transporter activity|amino acid derivative transmembrane transporter activity Enables the transfer of modified amino acids from one side of a membrane to the other. GO:0072348 sulfur compound transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072348 sulfur-containing compound transport The directed movement of compounds that contain sulfur, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0072347 response to anesthetic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072347 response to anaesthetic Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anesthetic stimulus. An anesthetic is a substance that causes loss of feeling, awareness, or sensation. GO:0072346 cADPR-sensitive calcium-release channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0072346 Enables the transmembrane transfer of a calcium ion by a channel that opens when cyclic adenosine diphosphate ribose (cADPR) has been bound by the channel complex or one of its constituent parts. GO:0072345 NAADP-sensitive calcium-release channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0072345 Reactome:R-HSA-2685505 Enables the transmembrane transfer of a calcium ion by a channel that opens when nicotinic acid adenine dinucleotide phosphate (NAADP) has been bound by the channel complex or one of its constituent parts. GO:0072344 rescue of stalled ribosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072344 A process of translational elongation that takes place when a ribosome has stalled during translation, and results in freeing the ribosome from the stalled translation complex. GO:0072343 pancreatic stellate cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072343 The multiplication or reproduction of pancreatic stellate cells, resulting in the expansion of a pancreatic stellate cell population. Pancreatic stellate cells are found in the periacinar space of the exocrine pancreas and in perivascular and periductal regions of the pancreas, and have long cytoplasmic processes that encircle the base of the acinus. GO:0072375 medium-term memory biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072375 MTM|middle-term memory The memory process that deals with the storage, retrieval and modification of information received at a time ago that is intermediate between that of short and long term memory (30min - 7hrs in Drosophila melanogaster). GO:0072374 carotene epsilon hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0072374 EC:1.14.99.- Catalysis of the reaction: a carotene + NADPH + O2 + H+ = a beta-ring hydroxylcarotene + NADP+ + H2O. Adds a hydroxyl group to the epsilon ring of the alpha-carotene. GO:0072373 alpha-carotene epsilon hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0072373 EC:1.14.99.- Catalysis of the reaction: alpha-carotene + NADPH + O2 + H+ = alpha-cryptoxanthin + NADP+ + H2O. GO:0072372 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0072372 GO:0072371 histone kinase activity (H2A-S121 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0072371 histone serine kinase activity (H2A-S121 specific)|histone-serine kinase activity (H2A-S121 specific) Catalysis of the transfer of a phosphate group to the serine-121 residue of the N-terminal tail of histone H2A. GO:0072370 histone H2A-S121 phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072370 histone H2A phosphorylation at S121|histone H2AS121 phosphorylation The modification of histone H2A by the addition of an phosphate group to a serine residue at position 121 of the histone. CHEBI:132683 (5S)-hydroperoxy-(14R,15S)-epoxy-(6E,8Z,11Z)-icosatrienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132683 CHEBI:132685 phosphatidylglycerol 36:0 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132685 CHEBI:132684 phosphatidylglycerol 13:0 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132684 CHEBI:132687 phosphatidylglycerol 38:1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132687 CHEBI:132686 phosphatidylglycerol 37:0 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132686 GO:0072379 ER membrane insertion complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0072379 endoplasmic reticulum membrane insertion complex A protein complex that is involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum. TA membrane proteins, also called type II transmembrane proteins, contain a single C-terminal transmembrane region. Some ER membrane insertion complex subunits are conserved between different species such as mammals and budding yeast. CHEBI:50299 canonical ribonucleotide residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50299 GO:0072378 blood coagulation, fibrin clot formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072378 A protein activation cascade that contributes to blood coagulation and consists of the cascade of enzymatic reactions initiated by physical damage to the wall of a blood vessel, leading to the formation of a formation of a fibrin clot at the site of the injury. The process also includes numerous positive and negative regulatory events. CHEBI:50298 canonical deoxyribonucleotide residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50298 CHEBI:50297 canonical nucleotide residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50297 GO:0072377 blood coagulation, common pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072377 A protein activation cascade that contributes to blood coagulation and consists of events leading from the formation of activated factor X to the formation of active thrombin, the cleavage of fibrinogen by thrombin, and the formation of cleaved fibrin into a stable multimeric, cross-linked complex. CHEBI:132681 (12S)-hydroperoxy-(14S,15R)-epoxy-(5Z,8Z,10E)-icosatrienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132681 GO:0072376 protein activation cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072376 protein activitory cascade|protein activation pathway A response to a stimulus that consists of a sequential series of modifications to a set of proteins where the product of one reaction acts catalytically in the following reaction. The magnitude of the response is typically amplified at each successive step in the cascade. Modifications typically include proteolysis or covalent modification, and may also include binding events. GO:0072364 obsolete regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072364 regulation of cellular ketone metabolic process by regulation of transcription from an RNA polymerase II promoter|regulation of cellular ketone metabolism by regulation of transcription from an RNA polymerase II promoter OBSOLETE. Any process that modulates the frequency, rate or extent of a cellular ketone metabolic process by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:0072363 obsolete regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072363 regulation of glycolysis by positive regulation of transcription from an RNA polymerase II promoter OBSOLETE. Any process that modulates the frequency, rate or extent of glycolysis by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:0072362 obsolete regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072362 regulation of glycolysis by negative regulation of transcription from an RNA polymerase II promoter OBSOLETE. Any process that modulates the frequency, rate or extent of glycolysis by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:0072361 obsolete regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072361 OBSOLETE. Any process that modulates the frequency, rate or extent of glycolysis by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:0072360 vascular cord development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072360 The progression of the vascular cord over time from its initial formation until its mature state. The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis. CHEBI:49299 D-fructofuranose 1,6-bisphosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49299 CHEBI:49298 N-formyl-L-methionyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49298 CHEBI:50284 lavandulyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50284 CHEBI:50281 lavandulol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50281 GO:0072369 obsolete regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072369 regulation of lipid transport by positive regulation of transcription from an RNA polymerase II promoter OBSOLETE. Any process that modulates the frequency, rate or extent of lipid transport by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:0072368 obsolete regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072368 regulation of lipid transport by negative regulation of transcription from an RNA polymerase II promoter OBSOLETE. Any process that modulates the frequency, rate or extent of lipid transport by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:0072367 obsolete regulation of lipid transport by regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072367 regulation of lipid transport by regulation of transcription from an RNA polymerase II promoter OBSOLETE. Any process that modulates the frequency, rate or extent of lipid transport by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:0072366 obsolete regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072366 regulation of cellular ketone metabolic process by positive regulation of transcription from an RNA polymerase II promoter|regulation of cellular ketone metabolism by positive regulation of transcription from an RNA polymerase II promoter OBSOLETE. Any process that modulates the frequency, rate or extent of a cellular ketone metabolic process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:0072365 obsolete regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from an RNA polymerase II promoter|regulation of cellular ketone metabolism by negative regulation of transcription from an RNA polymerase II promoter OBSOLETE. Any process that modulates the frequency, rate or extent of a cellular ketone metabolic process by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:0072397 detection of stimulus involved in cytokinesis checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072397 cytokinesis checkpoint sensor mechanism|septin checkpoint sensor process|cytokinesis checkpoint sensor process|detection of stimulus involved in septin checkpoint|sensing involved in septin checkpoint|sensing involved in cytokinesis checkpoint|septin checkpoint sensor mechanism The series of events in which information about the formation and integrity of cytokinetic structures, such as the contractile ring, is received and converted into a molecular signal, contributing to a cytokinesis checkpoint. GO:0072396 response to cell cycle checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072396 G1/S transition checkpoint effector process|response to G2/M transition checkpoint signaling|response to signal involved in G1/S transition checkpoint|response to signal involved in cell cycle checkpoint|response to signal involved in G2/M transition checkpoint|cell cycle checkpoint effector process|G2/M transition checkpoint effector process|response to G1/S transition checkpoint signaling A process that occurs in response to signals generated as a result of cell cycle checkpoint signaling. CHEBI:50279 (1S,2S,3S)-prephytoene diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50279 GO:0072395 signal transduction involved in cell cycle checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072395 signal transduction involved in G2/M transition checkpoint A signal transduction process that contributes to a cell cycle checkpoint. GO:0072394 detection of stimulus involved in cell cycle checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072394 detection of stimulus involved in G1/S transition checkpoint|detection of stimulus involved in G2/M transition checkpoint|sensing involved in G1/S transition checkpoint|G2/M transition checkpoint sensor mechanism|sensing involved in G2/M transition checkpoint|cell cycle checkpoint sensor mechanism|G1/S transition checkpoint sensor mechanism|G2/M transition checkpoint sensor process|sensing involved in cell cycle checkpoint|cell cycle checkpoint sensor process|G1/S transition checkpoint sensor process The series of events in which information about a biological process or quality is received and converted into a molecular signal, contributing to a cell cycle checkpoint. GO:0072393 microtubule anchoring at microtubule organizing center biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072393 microtubule anchoring at MTOC|microtubule anchoring at microtubule organising centre Any process in which a microtubule is maintained in a specific location in a cell by attachment to a microtubule organizing center. GO:0072392 phenol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072392 The chemical reactions and pathways resulting in the breakdown of phenol, a compound that consists of a benzene ring with one attached hydroxyl group. GO:0072391 phenol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072391 The chemical reactions and pathways resulting in the formation of phenol, a compound that consists of a benzene ring with one attached hydroxyl group. GO:0072390 phenol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072390 The chemical reactions and pathways involving phenol, a compound that consists of a benzene ring with one attached hydroxyl group. CHEBI:49284 cis-hex-3-enoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49284 CHEBI:49283 3-hexenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49283 CHEBI:49285 trans-hex-3-enoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49285 CHEBI:49289 humulene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49289 CHEBI:49290 gamma-humulene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49290 CHEBI:50273 (R,R)-chrysanthemyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50273 CHEBI:50272 chrysanthemyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50272 CHEBI:50271 (1R,2S,5S,6S)-2-(3-carboxypropanoyl)-5-[(1-carboxyvinyl)oxy]-6-hydroxycyclohex-3-ene-1-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50271 CHEBI:50277 farnesyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50277 CHEBI:50276 EC 5.99.1.2 (DNA topoisomerase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50276 GO:0072399 response to cytokinesis checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072399 cytokinesis checkpoint effector process|response to signal involved in cytokinesis checkpoint A process that occurs in response to signals generated as a result of cytokinesis checkpoint signaling. GO:0072398 signal transduction involved in cytokinesis checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072398 A signal transduction process that contributes to a cytokinesis checkpoint. CHEBI:50274 secoiridoid glycoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50274 GO:0072386 plus-end-directed organelle transport along microtubule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072386 microtubule plus-end-directed organelle localization|microtubule plus-end-directed organelle distribution The directed movement of an organelle towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination. GO:0072385 minus-end-directed organelle transport along microtubule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072385 microtubule minus-end-directed organelle distribution|microtubule minus-end-directed organelle localization The directed movement of an organelle towards the minus end of a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination. CHEBI:50269 EC 1.1.1.1 (alcohol dehydrogenase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50269 GO:0072384 organelle transport along microtubule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072384 microtubule-based organelle localization The directed movement of an organelle along a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination. CHEBI:50268 GABA modulator biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50268 GO:0072383 plus-end-directed vesicle transport along microtubule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072383 microtubule plus-end-directed vesicle localization|microtubule plus-end-directed vesicle distribution The directed movement of a vesicle towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination. CHEBI:50267 protective agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50267 GO:0072382 minus-end-directed vesicle transport along microtubule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072382 microtubule minus-end-directed vesicle distribution|microtubule minus-end-directed vesicle localization The directed movement of a vesicle towards the minus end of a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination. GO:0072381 positive regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072381 positive regulation of canonical Wnt-activated signaling pathway involved in neural crest cell differentiation|positive regulation of canonical Wnt receptor signaling pathway involved in neural crest cell differentiation|positive regulation of Wnt receptor signaling pathway through beta-catenin involved in neural crest cell differentiation|positive regulation of canonical Wnt receptor signalling pathway involved in neural crest cell differentiation Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin involved in neural crest cell differentiation. The Wnt signaling pathway is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. GO:0072380 TRC complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0072380 TMD recognition complex An ER membrane insertion complex that contains subunits that recognize two types of transmembrane domain signals. In budding yeast the complex contains Get4p, Get5p, Sgt2p, and at least two heat shock proteins (HSPs). CHEBI:49273 cholenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49273 CHEBI:49272 selinene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49272 CHEBI:49275 chol-4-en-24-oic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49275 CHEBI:49274 (-)-beta-selinene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49274 CHEBI:49277 chola-4,6-dien-24-oic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49277 CHEBI:49276 beta-selinene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49276 CHEBI:49279 (+)-delta-selinene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49279 CHEBI:49278 delta-selinene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49278 CHEBI:132671 (12S)-hydroperoxy-(14R,15S)-epoxy-(5Z,8Z,10E)-icosatrienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132671 CHEBI:49280 (-)-delta-selinene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49280 CHEBI:132678 11-hydroxy-(12S,13S)-epoxy-(9Z)-octadecenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132678 CHEBI:50262 2-(3-methylthiopropyl)malic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50262 CHEBI:50261 2-(2-methylthioethyl)malic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50261 CHEBI:50260 5-methylthio-2-oxopentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50260 CHEBI:50266 prodrug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50266 GO:0072389 flavin adenine dinucleotide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072389 flavin adenine dinucleotide catabolism|FAD or FADH2 catabolic process|flavin adenine dinucleotide degradation|flavin adenine dinucleotide breakdown The chemical reactions and pathways resulting in the breakdown of flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes. GO:0072388 flavin adenine dinucleotide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072388 flavin adenine dinucleotide biosynthesis|FAD or FADH2 biosynthetic process|flavin adenine dinucleotide anabolism|flavin adenine dinucleotide synthesis|flavin adenine dinucleotide formation The chemical reactions and pathways resulting in the formation of flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes. GO:0072387 flavin adenine dinucleotide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072387 flavin adenine dinucleotide metabolism|flavin-adenine dinucleotide metabolic process|FAD or FADH2 metabolic process The chemical reactions and pathways involving flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes. CHEBI:50263 2-hydroxydicarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50263 GO:0106155 peptidyl-lysine 3-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106155 RHEA:57153 Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 3-hydroxy-L-lysine + succinate + CO2. GO:0106154 perithecium formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106154 The process of producing flask-shaped fruiting bodies, called perithecia. In the ascomycetous fungi such as Neurospora crassa and Sordaria macrospora, these perithecia are formed in the sexual phase and they discharge ascospores through the ostiolum at the tip of the perithecial neck. GO:0106153 phosphorylated histone binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106153 Interacting selectively and non-covalently with a histone in which a residue has been modified by phosphorylation. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. CHEBI:74228 3-oxotriacontanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74228 GO:0106159 regulation of small RNA loading onto RISC biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106159 Any process that modulates the frequency, rate or extent small RNA loading onto RISC. GO:0106158 glycero-3-phosphocholine acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106158 RHEA:58476|BRENDA:EC2.3.1.B36 GPACT activity|glycero-3-phosphocholine acyltransferase activity|glycerophosphocholine O-acyltransferase activity Catalysis of the reaction:acyl-CoA + glycerophosphocholine = CoA + 1-acyl-sn-glycero-3-phosphocholine. CHEBI:74229 (11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74229 GO:0106157 peptidyl-arginine 3-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106157 Proposed def: Catalysis of the reaction: protein L-arginie + 2-oxoglutarate + O2 = protein 3-hydroxy-L-arginine + succinate + CO2. GO:0106156 peptidyl-lysine 4-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106156 Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 4-hydroxy-L-lysine + succinate + CO2. UBERON:0036376 wall of left ureter biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036376 left ureteral wall UBERON:0036375 wall of right ureter biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036375 right ureteral wall CHEBI:15929 (-)-methyl jasmonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15929 CHEBI:15926 dolichyl diphosphooligosaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15926 CHEBI:15925 2-dehydro-3-deoxy-6-phospho-D-gluconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15925 CHEBI:15927 N-ribosylnicotinamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15927 CL:1000296 epithelial cell of urethra biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000296 An epithelial cell that is part of the urethra. CHEBI:15920 columbamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15920 CHEBI:74220 C17 sphingosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74220 GO:0106162 mRNA N-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106162 RHEA:58480 Catalysis of the reaction: a cytidine in mRNA + acetyl-CoA + ATP + H2O = ADP + an N(4)-acetylcytidine in mRNA + CoA + H(+) + phosphate. CHEBI:74222 gamma-lactam biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74222 GO:0106161 positive regulation of small RNA loading onto RISC biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106161 Any process that activates or increases the frequency, rate or extent of small RNA loading onto RISC. GO:0106160 negative regulation of small RNA loading onto RISC biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106160 Any process that stops, prevents or reduces the frequency, rate or extent of small RNA loading onto RISC. CHEBI:74224 genistein(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74224 CHEBI:74223 pyrrolidin-2-ones biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74223 GO:0106166 spindle pole body-nuclear membrane anchor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106166 spindle pole body nuclear membrane anchor activity|nuclear membrane-spindle pole body anchor activity The binding activity of a molecule that brings together a mitotic spindle pole body and the nuclear membrane, in order to maintain specific membrane location of the spindle pole body. CHEBI:74237 phosphatidylinositol 34:1(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74237 GO:0106165 negative regulation of exonucleolytic catabolism of deadenylated mRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106165 Any process that stops, prevents, or reduces the frequency, rate or extent of exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay. GO:0106164 positive regulation of exonucleolytic catabolism of deadenylated mRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106164 Any process that activates or increases the frequency, rate or extent of exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay. GO:0106163 regulation of exonucleolytic catabolism of deadenylated mRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106163 Any process that modulates the frequency, rate or extent of exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay. CHEBI:74238 phosphatidylinositol 34:2(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74238 GO:0106167 extracellular ATP signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106167 A series of molecular signals mediated by the detection of extracellular ATP. GO:0047306 D-methionine-pyruvate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047306 RHEA:23836|EC:2.6.1.41|KEGG_REACTION:R03001|MetaCyc:2.6.1.41-RXN D-methionine aminotransferase activity|D-methionine-pyruvate aminotransferase activity|D-methionine transaminase activity|D-methionine--pyruvate aminotransferase activity|D-methionine:pyruvate aminotransferase activity Catalysis of the reaction: D-methionine + pyruvate = 4-methylthio-2-oxobutanoate + L-alanine. CHEBI:15919 N(6)-(1,2-dicarboxyethyl)-AMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15919 GO:0047305 (R)-3-amino-2-methylpropionate-pyruvate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047305 EC:2.6.1.40|KEGG_REACTION:R02050|RHEA:18393|MetaCyc:2.6.1.40-RXN|Reactome:R-HSA-909780 (R)-3-amino-2-methylpropionate transaminase activity|D-3-aminoisobutyrate--pyruvate aminotransferase activity|(R)-3-amino-2-methylpropionate--pyruvate aminotransferase activity|D-AIBAT activity|D-3-aminoisobutyrate-pyruvate transaminase activity|(R)-3-amino-2-methylpropanoate aminotransferase activity|(R)-3-amino-2-methylpropanoate:pyruvate aminotransferase activity|D-3-aminoisobutyrate--pyruvate transaminase activity|beta-aminoisobutyrate-pyruvate aminotransferase activity|beta-aminoisobutyrate--pyruvate transaminase activity|(R)-3-amino-2-methylpropionate-pyruvate aminotransferase activity|(R)-3-amino-2-methylpropanoate transaminase activity|D-beta-aminoisobutyrate:pyruvate aminotransferase activity Catalysis of the reaction: (2R)-3-amino-2-methylpropanoate + pyruvate = 2-methyl-3-oxopropanoate + L-alanine. CHEBI:15918 2'-deoxycytosine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15918 GO:0047304 2-aminoethylphosphonate-pyruvate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047304 EC:2.6.1.37|KEGG_REACTION:R04152|MetaCyc:2.6.1.37-RXN|RHEA:17021 (2-aminoethyl)phosphonate--pyruvate aminotransferase activity|(2-aminoethyl)phosphonate aminotransferase activity|2-aminoethylphosphonate-pyruvate aminotransferase activity|2-aminoethylphosphonate--pyruvate aminotransferase activity|(2-aminoethyl)phosphonate:pyruvate aminotransferase activity|(2-aminoethyl)phosphonic acid aminotransferase activity|(2-aminoethyl)phosphonate transaminase activity|2-aminoethylphosphonate aminotransferase activity Catalysis of the reaction: (2-aminoethyl)phosphonate + pyruvate = L-alanine + phosphonoacetaldehyde. GO:0047303 glycine-oxaloacetate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047303 EC:2.6.1.35|KEGG_REACTION:R00373|RHEA:17141|MetaCyc:2.6.1.35-RXN glycine-oxalacetate aminotransferase activity|glycine:oxaloacetate aminotransferase activity|glycine-oxaloacetate aminotransferase activity|glycine--oxaloacetate aminotransferase activity Catalysis of the reaction: glycine + oxaloacetate = L-aspartate + glyoxylate. GO:0047302 UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047302 KEGG_REACTION:R04529|EC:2.6.1.34|RHEA:18713|MetaCyc:2.6.1.34-RXN UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose:2-oxoglutarate aminotransferase activity|UDP-4-amino-2-acetamido-2,4,6-trideoxyglucose transaminase activity|UDP-4-amino-2-acetamido-2,4,6-trideoxyglucose aminotransferase activity|uridine diphospho-4-amino-2-acetamido-2,4,6-trideoxyglucose aminotransferase activity Catalysis of the reaction: 2-oxoglutarate + UDP-2-acetamido-4-amino-2,4,6-trideoxy-D-glucose = L-glutamate + UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose. CHEBI:15915 ADP-L-glycero-D-manno-heptose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15915 GO:0047301 valine-3-methyl-2-oxovalerate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047301 RHEA:11468|EC:2.6.1.32|KEGG_REACTION:R02200|MetaCyc:2.6.1.32-RXN L-valine:(S)-3-methyl-2-oxopentanoate aminotransferase activity|valine-3-methyl-2-oxovalerate aminotransferase activity|valine--isoleucine transaminase activity|valine--3-methyl-2-oxovalerate aminotransferase activity|valine--isoleucine aminotransferase activity|valine-2-keto-methylvalerate aminotransferase activity Catalysis of the reaction: (S)-3-methyl-2-oxopentanoate + L-valine = 3-methyl-2-oxobutanoate + L-isoleucine. CHEBI:15914 2-amino-4-oxopentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15914 CHEBI:15917 N-(D-glucopyranosyl)nicotinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15917 GO:0047300 pyridoxamine-pyruvate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047300 KEGG_REACTION:R01712|RHEA:12841|EC:2.6.1.30|MetaCyc:2.6.1.30-RXN pyridoxamine-pyruvate aminotransferase activity|pyridoxamine:pyruvate aminotransferase activity|pyridoxamineu-pyruvic transaminase activity|pyridoxamine-pyruvic transaminase|pyridoxamine--pyruvate aminotransferase activity Catalysis of the reaction: pyridoxamine + pyruvate = L-alanine + pyridoxal. CHEBI:15916 serine phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15916 CHEBI:15911 desulfoglucotropeolin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15911 CHEBI:15913 (R)-2-hydroxyoctadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15913 GO:0047309 dihydroxyphenylalanine transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047309 EC:2.6.1.49|KEGG_REACTION:R02077|MetaCyc:2.6.1.49-RXN|RHEA:15273 glutamate-DOPP transaminase (GDT)|dihydroxyphenylalanine aminotransferase activity|L-dopa transaminase activity|dopa transaminase activity|3,4-dihydroxy-L-phenylalanine:2-oxoglutarate aminotransferase activity|aspartate-DOPP transaminase (ADT)|phenylalanine-DOPP transaminase (PDT)|DOPA aminotransferase activity Catalysis of the reaction: 2-oxoglutarate + L-dopa = 3,4-dihydroxyphenylpyruvate + L-glutamate. GO:0047308 alanine-oxomalonate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047308 RHEA:18809|EC:2.6.1.47|KEGG_REACTION:R02970|MetaCyc:2.6.1.47-RXN L-alanine:oxomalonate aminotransferase activity|L-alanine-ketomalonate transaminase activity|alanine-oxomalonate aminotransferase activity|alanine--oxomalonate aminotransferase activity|alanine-ketomalonate (mesoxalate) transaminase activity Catalysis of the reaction: L-alanine + oxomalonate = aminomalonate + pyruvate. GO:0047307 diaminobutyrate-pyruvate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047307 EC:2.6.1.46|KEGG_REACTION:R02293|RHEA:12380|MetaCyc:2.6.1.46-RXN L-diaminobutyric acid transaminase activity|diaminobutyrate-pyruvate aminotransferase activity|diaminobutyrate--pyruvate aminotransferase activity|L-2,4-diaminobutanoate:pyruvate aminotransferase activity Catalysis of the reaction: L-2,4-diaminobutyrate + pyruvate = L-alanine + L-aspartate 4-semialdehyde. CL:1000281 smooth muscle cell of cecum biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000281 smooth muscle fiber of cecum|non-striated muscle fiber of cecum A smooth muscle cell that is part of the cecum. CL:1000280 smooth muscle cell of colon biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000280 non-striated muscle fiber of colon A smooth muscle cell that is part of the colon. CHEBI:74231 phosphatidylinositol 32:0(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74231 CHEBI:74230 (13Z,16Z,19Z,22Z,25Z)-3-oxooctacosapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74230 GO:0106173 COPII-coated vesicle lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0106173 The volume enclosed by the membrane of a COPII-coated endocytic vesicle. CHEBI:74233 (13Z,16Z,19Z,22Z,25Z)-octacosapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74233 GO:0106172 COPI-coated vesicle lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0106172 The volume enclosed by the membrane of a COPI-coated endocytic vesicle. CHEBI:74232 phosphatidylinositol 34:0(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74232 SO:0001997 subtelomere biolink:SequenceFeature go-plus http://purl.obolibrary.org/obo/SO_0001997 A heterochromatic region of the chromosome, adjacent to the telomere (on the centromeric side) that contains repetitive DNA and sometimes genes and it is transcribed. GO:0106177 cyclic-GMP-AMP hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106177 RHEA:58808 Catalysis of the reaction: cyclic GMP-AMP + 2 H2O = AMP + GMP. CHEBI:74247 (15Z,18Z,21Z,24Z,27Z)-triacontapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74247 GO:0106176 clathrin-coated endocytic vesicle lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0106176 The volume enclosed by the membrane of a clathrin-coated endocytic vesicle. GO:0106175 phagolysosome vesicle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0106175 The lipid bylayer surrounding a phagolysosome. GO:0106174 phagolysosome vesicle lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0106174 The volume enclosed by the membrane of a phagolysosome. CHEBI:74249 (19Z,22Z,25Z,28Z,31Z)-3-oxotetratriacontapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74249 GO:0106179 obsolete translocase activity acting on inorganic cations and their chelates biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106179 EC:7.2.-.- OBSOLETE. Catalysis of the translocation of inorganic cations and their chelates. GO:0106178 obsolete translocase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106178 EC:7.-.-.- OBSOLETE. Catalysis the movement of ions or molecules across membranes or their separation within membranes. GO:0047317 N6-acetyl-beta-lysine transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047317 MetaCyc:2.6.1.65-RXN|RHEA:16889|EC:2.6.1.65 6-acetamido-3-aminohexanoate:2-oxoglutarate aminotransferase activity|N6-acetyl-beta-lysine aminotransferase activity|epsilon-acetyl-beta-lysine aminotransferase activity|N(6)-acetyl-beta-lysine aminotransferase activity Catalysis of the reaction: 2-oxoglutarate + 3-amino-6-acetamidohexanoate = L-glutamate + 3-oxo-6-acetamidohexanoate. GO:0047316 glutamine-phenylpyruvate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047316 RHEA:17593|MetaCyc:2.6.1.64-RXN|EC:2.6.1.64|KEGG_REACTION:R01375 glutamine-phenylpyruvate aminotransferase activity|glutamine transaminase K activity|glutamine--phenylpyruvate aminotransferase activity|L-glutamine:phenylpyruvate aminotransferase activity Catalysis of the reaction: keto-phenylpyruvate + L-glutamine = 2-oxoglutaramate + L-phenylalanine. GO:0047315 kynurenine-glyoxylate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047315 MetaCyc:2.6.1.63-RXN|KEGG_REACTION:R01957|EC:2.6.1.63|RHEA:19249 kynurenine--glyoxylate aminotransferase activity|kynurenine-glyoxylate aminotransferase activity|L-kynurenine:glyoxylate aminotransferase (cyclizing) Catalysis of the reaction: L-kynurenine + glyoxylate = 4-(2-aminophenyl)-2,4-dioxobutanoate + glycine. GO:0047314 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0047314 GO:0047313 aromatic-amino-acid-glyoxylate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047313 MetaCyc:2.6.1.60-RXN|RHEA:10900|EC:2.6.1.60 aromatic-amino-acid-glyoxylate aminotransferase activity|aromatic-amino-acid--glyoxylate aminotransferase activity|aromatic-amino-acid:glyoxylate aminotransferase activity Catalysis of the reaction: glyoxylate + an aromatic amino acid = L-glycine + an aromatic oxo acid. CHEBI:15948 lycopene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15948 GO:0047312 L-phenylalanine:pyruvate aminotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047312 MetaCyc:2.6.1.58-RXN|EC:2.6.1.58|Reactome:R-HSA-893593|KEGG_REACTION:R00692|RHEA:13053 phenylalanine(histidine):pyruvate aminotransferase activity|L-histidine:pyruvate aminotransferase activity|L-phenylalanine(L-histidine):pyruvate aminotransferase activity|phenylalanine (histidine) aminotransferase activity|histidine:pyruvate aminotransferase activity|phenylalanine(histidine) aminotransferase activity|L-phenylalanine:pyruvate transaminase activity|histidine aminotransferase activity|phenylalanine(histidine) transaminase activity Catalysis of the reaction: pyruvate + L-phenylalanine = phenylpyruvate + L-alanine. CHEBI:15947 N-acetyl-beta-D-glucosaminylamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15947 GO:0047311 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047311 MetaCyc:2.6.1.56-RXN|EC:2.6.1.56|KEGG_REACTION:R03502|RHEA:15497 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol:pyruvate aminotransferase activity|L-alanine-N-amidino-3-(or 5-)keto-scyllo-inosamine transaminase activity|guanidinoaminodideoxy-scyllo-inositol-pyruvate aminotransferase activity|1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol aminotransferase activity Catalysis of the reaction: 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol + pyruvate = 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol + L-alanine. GO:0047310 glutamine-scyllo-inositol transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047310 MetaCyc:2.6.1.50-RXN|RHEA:22920|KEGG_REACTION:R02781|EC:2.6.1.50 glutamine-scyllo-inosose transaminase activity|glutamine--scyllo-inosose transaminase activity|glutamine-scyllo-inosose aminotransferase activity|glutamine scyllo-inosose aminotransferase activity|glutamine--scyllo-inosose aminotransferase activity|L-glutamine-scyllo-inosose transaminase activity|L-glutamine-keto-scyllo-inositol aminotransferase activity|L-glutamine:2,4,6/3,5-pentahydroxycyclohexanone aminotransferase activity Catalysis of the reaction: 2,4,6/3,5-pentahydroxycyclohexanone + L-glutamine = 1-amino-1-deoxy-scyllo-inositol + 2-oxoglutaramate. CHEBI:15949 diphthamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15949 CHEBI:15944 6-O-methylnorlaudanosoline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15944 CL:0002485 retinal melanocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002485 A melanocyte of the retina. This cell type is distinct from pigmented retinal epithelium. CHEBI:15943 poly(glycerol phosphate) macromolecule biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15943 CL:0002484 epithelial melanocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002484 A melanocyte that produces pigment in the epithelium. CHEBI:15946 keto-D-fructose 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15946 CHEBI:15945 D-galactono-1,5-lactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15945 CL:0002489 double negative thymocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002489 double negative T cell|CD4-CD8- T cell A thymocyte that lacks expression of CD4 and CD8. CHEBI:15940 nicotinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15940 CL:0002488 trophoblast giant cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002488 giant trophoblast cell A trophoblast cell that has a large volume of cytoplasm, is polyploid and is usually mononuclear but is also occasionally multi-nucleate. This cell type is important in establishing maternal physiology and remodeling of the vasculature of the placenta. GO:0047319 aspartate-phenylpyruvate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047319 RHEA:14097|MetaCyc:2.6.1.70-RXN|KEGG_REACTION:R00695|EC:2.6.1.70 aspartate-phenylpyruvate aminotransferase activity|L-aspartate:phenylpyruvate aminotransferase activity|aspartate--phenylpyruvate aminotransferase activity Catalysis of the reaction: keto-phenylpyruvate + L-aspartate = L-phenylalanine + oxaloacetate. CHEBI:15942 2-aminobenzenesulfonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15942 GO:0047318 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0047318 CHEBI:15941 2,3-dihydroxy-2,3-dihydrobenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15941 CHEBI:74240 phosphatidylinositol 38:4(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74240 GO:0106180 obsolete translocase activty of hydrons biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106180 EC:7.1.-.- OBSOLETE. Catalysis of the translocation of hydrons (hydron being the general name for H+ in its natural abundance). GO:0106184 obsolete translocation activity acting on other compounds biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106184 EC:7.6.-.- OBSOLETE. Catalysis of the translocation of other compounds not included in EC:7.1 through EC:7.5 . GO:0106183 obsolete translocase activity acting on carbohydrates and their derivatives. biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106183 EC:7.5.-.- OBSOLETE. Catalysis of the translocation of carbohydrates and their derivatives. CHEBI:74243 1-octadecanoyl-sn-glycero-3-phospho-D-myo-inositol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74243 GO:0106182 obsolete translocase activity acting on amino acids and peptides. biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106182 EC:7.4.-.- OBSOLETE. Catalysis of the translocation of amino acids and peptides. CHEBI:74246 (15Z,18Z,21Z,24Z,27Z)-3-oxotriacontapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74246 CL:0002483 hair follicle melanocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002483 A melanocyte that produces pigment within the hair follicle. GO:0106181 obsolete translocase activity acting on inorganic anions biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106181 EC:7.3.-.- OBSOLETE. Catalysis of the translocation of inorganic anions. CHEBI:74245 1-octadecanoyl-2-(5Z,8Z,11Z,14Z,17Z-eicosapentaenoyl)-sn-glycero-3-phospho-D-myo-inositol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74245 GO:0047320 D-4-hydroxyphenylglycine transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047320 RHEA:15589|KEGG_REACTION:R04234|EC:2.6.1.72|MetaCyc:2.6.1.72-RXN D-4-hydroxyphenylglycine:2-oxoglutarate aminotransferase activity|D-hydroxyphenylglycine aminotransferase activity|D-4-hydroxyphenylglycine aminotransferase activity Catalysis of the reaction: 2-oxoglutarate + D-4-hydroxyphenylglycine = 4-hydroxyphenylglyoxylate + L-glutamate. GO:0106188 obsolete translocase activity acting on hydrons linked the hydrolysis of a nucleoside triphosphate biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106188 EC:7.1.2.- OBSOLETE. Catalysis of the translocation of hydrons linked to the hydrolysis of a nucleoside triphosphate. CHEBI:74259 (17Z,20Z,23Z,26Z,29Z)-dotriacontapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74259 GO:0106187 obsolete translocase activity acting on hydrons linked to oxidoreductase reactions biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106187 EC:7.1.1.- OBSOLETE. Catalysis of the translocation of hydrons linked to an oxidoreduction reaction. GO:0106186 cytoplasmic side of plasma membrane, cell tip biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0106186 The leaflet the plasma membrane at the cell tip that faces the cytoplasm and any proteins embedded or anchored in it or attached to its surface. GO:0106185 histone H3-K37 methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106185 histone H3 K37 methylation|histone H3K37me|histone lysine H3 K37 methylation The modification of histone H3 by addition of one or more methyl groups to lysine at position 37 of the histone. GO:0106189 obsolete translocase activity acting on hydrons linked to the hydrolysis of a diphosphate biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106189 EC:7.1.3.- OBSOLETE. Catalysis of the translocation of hydrons linked to the hydrolysis of a diphosphate. GO:0047328 acyl-phosphate-hexose phosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047328 EC:2.7.1.61|RHEA:13077|MetaCyc:2.7.1.61-RXN acyl-phosphate:D-hexose phosphotransferase activity|hexose phosphate:hexose phosphotransferase activity Catalysis of the reaction: D-hexose + acyl phosphate = D-hexose phosphate + an acid. GO:0047327 glycerol-3-phosphate-glucose phosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047327 KEGG_REACTION:R00850|RHEA:21288|MetaCyc:2.7.1.142-RXN|EC:2.7.1.142 sn-glycerol-3-phosphate:D-glucose 6-phosphotransferase activity Catalysis of the reaction: sn-glycerol 3-phosphate + D-glucose = D-glucose 6-phosphate + glycerol. UBERON:0012375 subserosa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012375 A layer of tissue between the muscularis and serosa. GO:0047326 inositol tetrakisphosphate 5-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047326 Reactome:R-HSA-1855228|MetaCyc:2.7.1.140-RXN|EC:2.7.1.140|RHEA:12717 inositol-tetrakisphosphate 5-kinase activity|inositol 1,3,4,6-tetrakisphosphate 5-kinase activity|ATP:1D-myo-inositol-1,3,4,6-tetrakisphosphate 5-phosphotransferase activity|1D-myo-inositol-tetrakisphosphate 5-kinase activity Catalysis of the reaction: 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP. UBERON:0012373 sympathetic nerve plexus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012373 A nerve plexus that is part of a sympathetic nervous system. GO:0047325 inositol tetrakisphosphate 1-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047325 Reactome:R-HSA-1855162|MetaCyc:2.7.1.134-RXN|RHEA:12452|EC:2.7.1.134|Reactome:R-HSA-994137 inositol-tetrakisphosphate 1-kinase activity|inositol 3,4,5,6-tetrakisphosphate 1-kinase activity|1D-myo-inositol-tetrakisphosphate 1-kinase activity|1D-myo-inositol-trisphosphate 6-kinase activity|1D-myo-inositol-trisphosphate 5-kinase activity|inositol-trisphosphate 6-kinase activity|inositol-trisphosphate 5-kinase activity|ATP:1D-myo-inositol-3,4,5,6-tetrakisphosphate 1-phosphotransferase activity Catalysis of the reaction: 1D-myo-inositol 3,4,5,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP. GO:0047324 phosphoenolpyruvate-glycerone phosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047324 KEGG_REACTION:R01012|MetaCyc:2.7.1.121-RXN|EC:2.7.1.121|RHEA:18381 phosphoenolpyruvate:glycerone phosphotransferase activity Catalysis of the reaction: glycerone + phosphoenolpyruvate = glycerone phosphate + pyruvate. CHEBI:15937 trans-5-O-(4-coumaroyl)-D-quinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15937 GO:0047323 [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047323 MetaCyc:2.7.11.4-RXN|RHEA:17301|Reactome:R-HSA-5693148|EC:2.7.11.4 branched-chain oxo acid dehydrogenase kinase (phosphorylating) activity|[3-methyl-2-oxobutanoate dehydrogenase (lipoamide)] kinase activity|BCK|branched-chain alpha-ketoacid dehydrogenase kinase activity|STK2|BCKD kinase activity|3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase activity|ATP:3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) phosphotransferase activity|BCODH kinase activity|branched-chain 2-oxo acid dehydrogenase kinase activity|branched-chain keto acid dehydrogenase kinase activity Catalysis of the reaction: ATP + 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) = ADP + 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) phosphate. CHEBI:15936 aldehydo-D-xylose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15936 GO:0047322 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047322 RHEA:23172|EC:2.7.11.31|MetaCyc:2.7.1.109-RXN 3-hydroxy-3-methylglutaryl coenzyme A reductase kinase activity|hydroxymethylglutaryl coenzyme A reductase kinase activity|beta-hydroxy-beta-methylglutaryl-CoA reductase kinase activity|HMG-CoA reductase kinase activity|hydroxymethylglutaryl coenzyme A reductase kinase (phosphorylating) activity|hydroxymethylglutaryl-CoA reductase (NADPH) kinase activity|STK29|ATP:hydroxymethylglutaryl-CoA reductase (NADPH) phosphotransferase activity|hydroxymethylglutaryl-CoA reductase kinase activity|3-hydroxy-3-methylglutaryl-CoA reductase kinase activity|AMPK|hydroxymethylglutaryl-CoA reductase (NADPH2) kinase activity|reductase kinase activity Catalysis of the reaction: [3-hydroxy-3-methylglutaryl-CoA reductase (NADPH)] + ATP = [3-hydroxy-3-methylglutaryl-CoA reductase (NADPH)] phosphate + ADP. UBERON:0012378 muscle layer of urinary bladder biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012378 muscular layer of bladder|tunica musculari vesicae|bladder muscular coat|muscular coat of urinary bladder|muscle layer of urinary bladder|muscular coat of bladder|tunica muscularis (vesica urinaria)|muscular layer of urinary bladder A muscular coat that is part of a urinary bladder. CHEBI:15939 glycyrrhizinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15939 GO:0047321 diphosphate-protein phosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047321 MetaCyc:2.7.99.1-RXN|EC:2.7.99.1 pyrophosphate-protein phosphotransferase activity|DiPPT|triphosphate-protein phosphotransferase activity|pyrophosphate:protein phosphotransferase activity|diphosphate:microsomal-membrane-protein O-phosphotransferase activity|triphosphate:microsomal-membrane-protein phosphotransferase activity Catalysis of the reaction: microsomal-membrane protein + diphosphate = diphosphate + O-phospho-microsomal-membrane protein. CHEBI:15938 pregnan-21-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15938 CL:0002496 intraepithelial lymphocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002496 intraepithelial T-cell|intraepithelial T cell|IEL A T cell that is located in the intestinal epithelium and is capable of a mucosal immune response. CHEBI:15933 UDP-D-apiose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15933 CHEBI:15932 apiin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15932 CHEBI:15935 N-acetyl-D-glucosaminylphosphatidylinositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15935 CHEBI:15934 5-amino-6-(D-ribitylamino)uracil biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15934 CL:0002499 spongiotrophoblast cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002499 A trophoblast cell that arises in the junctional zone (basal plate) of the placenta. CHEBI:15931 2-acetamido-2-deoxy-3-O-(4-deoxy-alpha-L-threo-hex-4-enopyranosyluronic acid)-4-O-sulfo-D-galactopyranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15931 GO:0047329 phosphoramidate-hexose phosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047329 RHEA:10972|EC:2.7.1.62|MetaCyc:2.7.1.62-RXN phosphoramidate-hexose transphosphorylase activity|phosphoramidic-hexose transphosphorylase activity|phosphoramidate:hexose 1-phosphotransferase activity Catalysis of the reaction: hexose + phosphoramidate = hexose 1-phosphate + NH3. CHEBI:15930 atrazine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15930 GO:0106191 obsolete translocase activity acting on inogranic cations linked to oxidoreductase reactions biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106191 EC:7.2.1.- OBSOLETE. Catalysis of the translocation of inorganic cations linked to oxidoreductase reactions. GO:0106190 obsolete translocase activity acting on hydrons linked to a decarboxylation reaction biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106190 EC:7.1.4.- OBSOLETE. Catalysis of the translocation of hydrons linked to a decarboxylation reaction. CHEBI:74252 rhizobactin 1021 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74252 GO:0106195 obsolete translocase activty acting on inorganic anions linked to oxidoreductase reactions biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106195 EC:7.3.1.- OBSOLETE. Catalysis of the translocation of inorganic anions linked to oxidoreductase reactions. GO:0106194 obsolete translocase activity acting on inorganic cations and their chelates linked to a decarboxylation reaction biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106194 EC:7.2.4.- OBSOLETE. Catalysis of the transocation of inorganic cations and their chelates linked to a decarboxylation reaction. CL:0002491 auditory epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002491 A specialized cell involved in auditory sensory perception. CHEBI:74254 (17Z,20Z,23Z,26Z,29Z)-3-oxodotriacontapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74254 GO:0106193 obsolete translocase activity acting on inorganic cations and their chelates linked to the hydrolysis of a diphosphate biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106193 EC:7.2.3.- OBSOLETE. Catalysis of the translocation of inorganic cations and their chelates linked to the hydrolysis of a diphosphate. CL:0002494 cardiocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002494 heart cell A cell located in the heart, including both muscle and non muscle cells. CHEBI:74257 FMN-L-threonine(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74257 GO:0106192 obsolete translocase activity acting on inorganic cations and their chelates linked to the hydrolysis of a nucleoside triphosphate biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106192 EC:7.2.2.- OBSOLETE. Catalysis of the translocation of inorganic cations and their chelates linked to the hydrolysis of a nucleoside triphosphate. GO:0106111 regulation of mitotic cohesin ssDNA (lagging strand) loading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106111 Any process that modulates the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading. GO:0047331 diphosphate-glycerol phosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047331 EC:2.7.1.79|RHEA:13689|KEGG_REACTION:R01044|MetaCyc:2.7.1.79-RXN diphosphate:glycerol 1-phosphotransferase activity|PPi-glycerol phosphotransferase activity|pyrophosphate--glycerol phosphotransferase activity Catalysis of the reaction: glycerol + diphosphate = glycerol 1-phosphate + H(+) + phosphate. GO:0047330 polyphosphate-glucose phosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047330 MetaCyc:2.7.1.63-RXN|RHEA:22036|EC:2.7.1.63 polyphosphate:D-glucose 6-phosphotransferase activity|polyphosphate-D-(+)-glucose-6-phosphotransferase activity|polyphosphate glucokinase activity|polyphosphate-glucose 6-phosphotransferase activity Catalysis of the reaction: beta-D-glucose + long chain polyphosphate = glucose-6-phosphate + long chain polyphosphate. GO:0106110 vomitoxin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106110 deoxynivalenol biosynthetic process|DON biosynthetic process|vomitoxin anabolism|vomitoxin synthesis|vomitoxin biosynthesis|vomitoxin formation The chemical reactions and pathways resulting in the formation of type B trichothecene vomitoxin, a poisonous substance produced by some species of fungi and predominantly occurs in grains such as wheat, barley and oats. CHEBI:74269 guanosine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74269 GO:0106115 negative regulation of mitotic cohesin dsDNA (leading strand) loading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106115 Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading. GO:0106114 regulation of mitotic cohesin dsDNA (leading strand) loading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106114 Any process that modulates the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading. GO:0106113 positive regulation of mitotic cohesin ssDNA (lagging strand) loading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106113 Any process that activates or increases the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading. CHEBI:142091 (-)-eremophilene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142091 GO:0106112 negative regulation of mitotic cohesin ssDNA (lagging strand) loading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106112 Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading. GO:0047339 nucleoside-triphosphate-hexose-1-phosphate nucleotidyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047339 MetaCyc:2.7.7.28-RXN|EC:2.7.7.28 hexose 1-phosphate guanylyltransferase activity|NDP hexose pyrophosphorylase activity|nucleoside diphosphohexose pyrophosphorylase activity|NTP:hexose-1-phosphate nucleotidyltransferase activity|GTP:hexose-1-phosphate guanylyltransferase activity|guanosine diphosphohexose pyrophosphorylase activity|hexose 1-phosphate nucleotidyltransferase activity|NTP:alpha-D-aldose-1-phosphate nucleotidyltransferase activity|NDP-hexose pyrophosphorylase activity|NDP-hexose diphosphorylase activity|hexose-1-phosphate guanylyltransferase activity|hexose nucleotidylating enzyme activity|nucleoside-triphosphate-aldose-1-phosphate nucleotidyltransferase activity|GTP:alpha-D-hexose-1-phosphate guanylyltransferase activity|GDP hexose pyrophosphorylase activity Catalysis of the reaction: hexose 1-phosphate + nucleoside triphosphate = NDP-hexose + diphosphate. GO:0106119 negative regulation of sterol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106119 Any process that stops, prevents or reduces the frequency, rate or extent of a sterol biosynthetic process. GO:0047338 UTP:xylose-1-phosphate uridylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047338 MetaCyc:2.7.7.11-RXN|EC:2.7.7.11|RHEA:18389 xylose-1-phosphate uridylyltransferase activity|UTP:alpha-D-xylose-1-phosphate uridylyltransferase activity|uridine diphosphoxylose pyrophosphorylase activity|uridylyltransferase, xylose 1-phosphate|xylose 1-phosphate uridylyltransferase activity|UDP-xylose pyrophosphorylase activity|UTP-xylose-1-phosphate uridylyltransferase activity Catalysis of the reaction: alpha-D-xylose 1-phosphate + UTP = UDP-D-xylose + diphosphate. GO:0106118 regulation of sterol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106118 Any process that modulates the frequency, rate or extent of a sterol biosynthetic process. GO:0106117 acidocalcisome organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106117 polyphosphate vacuole organization|acidocalcisome organization and biogenesis|metachromatic granule organization|acidocalcisome biogenesis|volutin granule organization|acidocalcisome organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an acidocalcisome. An acidocalcisome is an electron-dense acidic membrane-bounded organelle which contains a matrix of pyrophosphate and polyphosphates with bound calcium and other cations. GO:0047337 dolichyl-diphosphate-polyphosphate phosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047337 MetaCyc:2.7.4.20-RXN|RHEA:19417|EC:2.7.4.20 dolichylpyrophosphate:polyphosphate phosphotransferase activity|dolichyl-diphosphate:polyphosphate phosphotransferase activity Catalysis of the reaction: dolichyl diphosphate + long-chain-polyphosphate = dolichol-phosphate + long-chain-polyphosphate. GO:0106116 positive regulation of mitotic cohesin dsDNA (leading strand) loading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106116 Any process that activates or increases the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading. GO:0047336 5-methyldeoxycytidine-5'-phosphate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047336 EC:2.7.4.19|KEGG_REACTION:R04235|RHEA:11396|MetaCyc:2.7.4.19-RXN ATP:5-methyldeoxycytidine-5'-phosphate phosphotransferase activity Catalysis of the reaction: 2'-deoxy-5-methyl-5'-cytidylate + ATP = 5-methyldeoxycytidine diphosphate + ADP + H(+). GO:0047335 3-phosphoglyceroyl-phosphate-polyphosphate phosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047335 MetaCyc:2.7.4.17-RXN|EC:2.7.4.17|RHEA:18665 1,3-diphosphoglycerate-polyphosphate phosphotransferase activity|3-phospho-D-glyceroyl-phosphate:polyphosphate phosphotransferase activity|diphosphoglycerate-polyphosphate phosphotransferase activity Catalysis of the reaction: long-chain-polyphosphate + 3-phospho-D-glyceroyl-phosphate = long-chain-polyphosphate + 3-phosphoglycerate. GO:0047334 diphosphate-fructose-6-phosphate 1-phosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047334 MetaCyc:2.7.1.90-RXN|RHEA:13613|EC:2.7.1.90 diphosphate:D-fructose-6-phosphate 1-phosphotransferase activity|inorganic pyrophosphate-dependent phosphofructokinase activity|pyrophosphate--fructose 6-phosphate 1-phosphotransferase activity|inorganic pyrophosphate-phosphofructokinase activity|pyrophosphate-fructose 6-phosphate phosphotransferase activity|pyrophosphate-dependent phosphofructo-1-kinase activity|6-phosphofructokinase (diphosphate) activity|6-phosphofructokinase (pyrophosphate) activity|diphosphate-dependent 6-phosphofructose-1-kinase activity|pyrophosphate-dependent 6-phosphofructose-1-kinase activity Catalysis of the reaction: fructose-6-phosphate + diphosphate = phosphate + fructose-1,6-bisphosphate. GO:0047333 dihydrostreptomycin-6-phosphate 3'-alpha-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047333 RHEA:16281|MetaCyc:2.7.1.88-RXN|EC:2.7.1.88|KEGG_REACTION:R03395 ATP:dihydrostreptomycin-6-P 3'alpha-phosphotransferase activity|dihydrostreptomycin 6-phosphate kinase (phosphorylating)|dihydrostreptomycin-6-phosphate 3'alpha-kinase activity|ATP:dihydrostreptomycin-6-phosphate 3'alpha-phosphotransferase activity Catalysis of the reaction: ATP + dihydrostreptomycin 6-phosphate = ADP + dihydrostreptomycin 3'alpha,6-bisphosphate + 2 H(+). GO:0047332 diphosphate-serine phosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047332 MetaCyc:2.7.1.80-RXN|RHEA:23764|KEGG_REACTION:R00584|EC:2.7.1.80 diphosphate:L-serine O-phosphotransferase activity|pyrophosphate--serine phosphotransferase activity|pyrophosphate-L-serine phosphotransferase activity Catalysis of the reaction: L-serine + diphosphate = O-phospho-L-serine + H(+) + phosphate. CL:0002463 SIRPa-positive adipose dendritic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002463 DC.SIRPa+.Ad An adipose dendritic cell that is SIRPa-positive. CL:0002462 adipose dendritic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002462 A F4/80-negative dendritic cell located in adipose tissue. UBERON:0036328 wall of coronary artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036328 coronary arterial wall CL:0002465 CD11b-positive dendritic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002465 A conventional dendritic cell that expresses CD11b (ITGAM). CL:0002464 SIRPa-negative adipose dendritic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002464 DC.SIRPa-.Ad An adipose dendritic cell that is SIRPa-negative. CL:0002467 Gr1-high myeloid suppressor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002467 MDS.Gr1hi A myeloid suppressor cell that is Gr1-high and CD11c-negative. CHEBI:74260 (19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74260 CL:0002469 MHC-II-negative classical monocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002469 Mo.6C+II- Gr1-high monocyte that lacks MHC-II receptor complex. CL:0002468 Gr1-low myeloid suppressor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002468 MDS.Gr1lo A myeloid suppressor cell that is Gr1-low and CD11c-positive. CHEBI:74262 (21Z,24Z,27Z,30Z,33Z)-hexatriacontapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74262 CHEBI:74261 (21Z,24Z,27Z,30Z,33Z)-3-oxohexatriacontapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74261 CHEBI:74264 (8Z,11Z,14Z)-icosatrienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74264 CHEBI:74263 (23Z,26Z,29Z,32Z,35Z)-3-oxooctatriacontapentaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74263 CHEBI:74266 N-acylurea biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74266 CHEBI:74265 (8Z,11Z,14Z,17Z)-icosatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74265 CHEBI:74268 N(1)-methylguanosine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74268 CL:0002460 CD8alpha-negative thymic conventional dendritic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002460 DC.8-.Th A conventional thymic dendritic cell that is CD8alpha-negative. CHEBI:74267 N(1)-methylguanosine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74267 GO:0106122 negative regulation of cobalamin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106122 Any process that stops, prevents or reduces the frequency, rate or extent of a cobalamin metabolic process. GO:0047342 galactose-1-phosphate thymidylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047342 EC:2.7.7.32|RHEA:17165|MetaCyc:2.7.7.32-RXN|KEGG_REACTION:R02329 galactose 1-phosphate thymidylyl transferase activity|dTTP:alpha-D-galactose-1-phosphate thymidylyltransferase activity|thymidine diphosphogalactose pyrophosphorylase activity|dTDP-galactose pyrophosphorylase activity|dTDP-galactose diphosphorylase activity|dTDP galactose pyrophosphorylase activity|thymidine triphosphate:alpha-D-galactose 1-phosphate thymidylyltransferase activity Catalysis of the reaction: alpha-D-galactose 1-phosphate + dTTP = diphosphate + dTDP-D-galactose. GO:0047341 fucose-1-phosphate guanylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047341 EC:2.7.7.30|Reactome:R-HSA-6787533|MetaCyc:2.7.7.30-RXN|RHEA:13549|KEGG_REACTION:R01951 GTP:beta-L-fucose-1-phosphate guanylyltransferase activity|guanosine diphosphate L-fucose pyrophosphorylase activity|GDP fucose pyrophosphorylase activity|GTP:L-fucose-1-phosphate guanylyltransferase activity|GDP-fucose pyrophosphorylase activity|GTP:fucose-1-phosphate guanylyltransferase activity|GDP-L-fucose pyrophosphorylase activity|GDP-fucose diphosphorylase activity Catalysis of the reaction: beta-L-fucose 1-phosphate + GTP = diphosphate + GDP-L-fucose. GO:0106121 positive regulation of cobalamin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106121 Any process that activates or increases the frequency, rate or extent of a cobalamin metabolic process. GO:0106120 positive regulation of sterol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106120 Any process that activates or increases the frequency, rate or extent of a sterol biosynthetic process. GO:0047340 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0047340 GO:0106126 reservosome membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0106126 The lipid bilayer surrounding a reservosome. GO:0106125 reservosome matrix biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0106125 A matrix composed of planar membranes, vesicles and lipid inclusions within the reservosome. GO:0106124 reservosome lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0106124 The volume enclosed by the membranes of a reservosome. GO:0106123 reservosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0106123 A large membrane-bound endocytic organelle present only in members of the Schizotrypanum subgenus of the Trypanosoma genus and is defined as the site of storage of endocytosed macromolecules and lysosomal enzymes. It is found at the posterior end of epimastigote forms of Trypanosoma cruzi, but absent in amastigotes and trypomastigotes. UBERON:0036343 wall of gallbladder biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036343 gallbladder wall GO:0047349 D-ribitol-5-phosphate cytidylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047349 KEGG_REACTION:R02921|RHEA:12456|EC:2.7.7.40|MetaCyc:2.7.7.40-RXN CTP:D-ribitol-5-phosphate cytidylyltransferase activity|ribitol 5-phosphate cytidylyltransferase activity|cytidine diphosphate ribitol pyrophosphorylase activity|CDP-ribitol pyrophosphorylase activity|cytidine diphosphoribitol pyrophosphorylase activity|CDP-ribitol diphosphorylase activity|CDP ribitol pyrophosphorylase activity Catalysis of the reaction: D-ribitol 5-phosphate + CTP = CDP-ribitol + diphosphate. GO:0106129 positive regulation of store-operated calcium entry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106129 Any process that activates or increases the frequency, rate or extent of store-operated calcium entry. GO:0047348 glycerol-3-phosphate cytidylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047348 EC:2.7.7.39|RHEA:13361|MetaCyc:2.7.7.39-RXN|KEGG_REACTION:R00856 CTP:glycerol-3-phosphate cytidylyltransferase activity|CTP:sn-glycerol-3-phosphate cytidylyltransferase activity|CTP:glycerol 3-phosphate cytidylyltransferase activity|Gro-PCT|cytidine diphosphoglycerol pyrophosphorylase activity|CDP-glycerol pyrophosphorylase activity|CDP-glycerol diphosphorylase activity|cytidine diphosphate glycerol pyrophosphorylase activity Catalysis of the reaction: sn-glycerol 3-phosphate + CTP = CDP-glycerol + diphosphate. GO:0106128 negative regulation of store-operated calcium entry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106128 Any process that stops, prevents or reduces the frequency, rate or extent of store-operated calcium entry. GO:0047347 aldose-1-phosphate nucleotidyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047347 EC:2.7.7.37|MetaCyc:2.7.7.37-RXN NDP:aldose-1-phosphate nucleotidyltransferase activity|sugar nucleotide phosphorylase activity|NDP-aldose phosphorylase activity|NDP:alpha-D-aldose-1-phosphate nucleotidyltransferase activity|NDPaldose phosphorylase activity|sugar phosphate nucleotidyltransferase activity|glucose 1-phosphate inosityltransferase activity|NDP-sugar phosphorylase activity|nucleoside diphosphosugar phosphorylase activity|NDP sugar phosphorylase activity|sugar-1-phosphate nucleotidyltransferase activity|nucleoside diphosphate sugar:orthophosphate nucleotidyltransferase activity Catalysis of the reaction: aldose 1-phosphate + NDP = phosphate + NDP-aldose. GO:0047346 aldose-1-phosphate adenylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047346 EC:2.7.7.36|MetaCyc:2.7.7.36-RXN ADP:aldose-1-phosphate adenylyltransferase activity|ADP-sugar phosphorylase activity|sugar-1-phosphate adenylyltransferase activity|ADP sugar phosphorylase activity|ADP-aldose phosphorylase activity|ADP:alpha-D-aldose-1-phosphate adenylyltransferase activity|adenosine diphosphosugar phosphorylase activity|ADPaldose phosphorylase activity|adenosine diphosphate glucose:orthophosphate adenylyltransferase activity Catalysis of the reaction: aldose 1-phosphate + ADP = phosphate + ADP-aldose. GO:0047345 ribose-5-phosphate adenylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047345 EC:2.7.7.35|KEGG_REACTION:R01052|MetaCyc:2.7.7.35-RXN|RHEA:14529 adenosine diphosphoribose phosphorylase activity|ADP ribose phosphorylase activity|ADP:ribose-5-phosphate adenylyltransferase activity|ADP:D-ribose-5-phosphate adenylyltransferase activity|ADP-ribose phosphorylase activity Catalysis of the reaction: D-ribose 5-phosphate + ADP + H(+) = ADP-ribose + phosphate. GO:0047344 glucose-1-phosphate guanylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047344 EC:2.7.7.34|RHEA:10708|MetaCyc:2.7.7.34-RXN|KEGG_REACTION:R00954 GDP-glucose pyrophosphorylase activity|GDP-glucose diphosphorylase activity|GTP:glucose-1-phosphate guanylyltransferase activity|guanosine diphosphoglucose pyrophosphorylase activity|GTP:alpha-D-glucose-1-phosphate guanylyltransferase activity|GDP glucose pyrophosphorylase activity Catalysis of the reaction: alpha-D-glucose 1-phosphate + GTP = diphosphate + GDP-D-glucose. GO:0047343 glucose-1-phosphate cytidylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047343 EC:2.7.7.33|RHEA:18213|MetaCyc:2.7.7.33-RXN|KEGG_REACTION:R00956 CTP:glucose-1-phosphate cytidylyltransferase activity|CTP:D-glucose-1-phosphate cytidylyltransferase activity|cytidine diphosphate glucose pyrophosphorylase activity|CDP-glucose pyrophosphorylase activity|CDP-glucose diphosphorylase activity|cytidine diphosphoglucose pyrophosphorylase activity|CTP:alpha-D-glucose-1-phosphate cytidylyltransferase activity|cytidine diphosphate-D-glucose pyrophosphorylase activity|CDP glucose pyrophosphorylase activity Catalysis of the reaction: alpha-D-glucose 1-phosphate + CTP = CDP-D-glucose + diphosphate. CL:0002474 lymphoid MHC-II-negative classical monocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002474 A MHC-II-negative classical monocyte located in lymphoid tissue that is F4/80-positive, CD11c-negative, and CD11b-high. CL:0002473 MHC-II-high non-classical monocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002473 Mo.6C-II+ Gr1-low non-classical monocyte that has high surface expression of a MHC-II complex. CL:1000245 posterior lateral line ganglion neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000245 CL:0002476 bone marrow macrophage biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002476 MF.BM A tissue-resident macrophage located in the bone marrow. This cell type is B220-negative, CD3e-negative, Ly-6C-negative, CD115-positive, F4/80-positive. CL:0002475 lymphoid MHC-II-negative non-classical monocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002475 A MHC-II-negative classical monocyte located in lymphoid tissue that is F4/80-positive, CD11c-intermediate, and CD11b-high. CL:0002478 F4/80-negative adipose macrophage biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002478 MF.Autofl.Ad An adipose macrophage that does not express F4/80but is MHC-II-positive. This cell type exhibits autofluorescence under typical flow cyometry conditions. CL:0002477 adipose macrophage biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002477 A macrophage located in adipose tissue that is CD45-positive, CD11c-positive, and SIRPa-positive. CHEBI:74271 4-demethylwyosine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74271 CL:0002479 F4/80-positive adipose macrophage biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002479 MF.F480+.Ad An adipose macrophage that does not express MHC-II but is F4/80-positive. CHEBI:74273 4-demethylwyosine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74273 CHEBI:74272 (R)-3-hydroxydecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74272 CHEBI:74275 7-[(3S)-(3-amino-3-methoxycarbonyl)propyl]wyosine 5'-phosphate zwitterion residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74275 CL:0002470 MHC-II-positive classical monocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002470 Mo.6c+II Gr1-high monocyte that has a MHC-II receptor complex. CHEBI:74276 (R)-3-hydroxylauroyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74276 CL:0002472 MHC-II-low non-classical monocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002472 Mo.6C-IIint Gr1-low non-classical monocyte that has low to intermediate expression of the MHC-II complex. CHEBI:74279 (R)-3-hydroxyoctanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74279 CHEBI:74278 (R)-3-hydroxypalmitoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74278 CL:0002471 MHC-II-negative non-classical monocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002471 Mo.6C-II- Gr1-low non-classical monocyte that lacks expression of a MHC-II complex. GO:0047353 N-methylphosphoethanolamine cytidylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047353 MetaCyc:2.7.7.57-RXN|RHEA:10576|EC:2.7.7.57|KEGG_REACTION:R03375 CTP:P-MEA cytidylyltransferase activity|monomethylethanolamine phosphate cytidylyltransferase activity|CTP:N-methylphosphoethanolamine cytidylyltransferase activity|CTP:N-methylethanolamine-phosphate cytidylyltransferase activity Catalysis of the reaction: N-methylethanolamine phosphate + CTP = CDP-N-methylethanolamine + diphosphate. GO:0047352 adenylylsulfate-ammonia adenylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047352 KEGG_REACTION:R01619|MetaCyc:2.7.7.51-RXN|EC:2.7.7.51|RHEA:19197 adenylylsulphate-ammonia adenylyltransferase activity|APSAT|adenylylsulfate:ammonia adenylyltransferase activity Catalysis of the reaction: 5'-adenylyl sulfate + NH(4)(+) = adenosine 5'-phosphoramidate + 2 H(+) + sulfate. GO:0047351 guanosine-triphosphate guanylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047351 MetaCyc:2.7.7.45-RXN|KEGG_REACTION:R00012|EC:2.7.7.45|RHEA:18153 GTP:GTP guanylyltransferase activity Catalysis of the reaction: 2 GTP = P(1),P(4)-bis(5'-guanosyl) tetraphosphate + diphosphate + H(+). GO:0047350 glucuronate-1-phosphate uridylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047350 MetaCyc:2.7.7.44-RXN|RHEA:16325|EC:2.7.7.44|KEGG_REACTION:R01381 UTP:1-phospho-alpha-D-glucuronate uridylyltransferase activity|UTP:glucuronate-1-phosphate uridylyltransferase activity|UDP-D-glucuronic acid pyrophosphorylase activity|uridine diphosphoglucuronic pyrophosphorylase activity|UDP-glucuronic acid pyrophosphorylase activity|UDP-glucuronate pyrophosphorylase activity Catalysis of the reaction: 1-phospho-alpha-D-glucuronate + UTP = diphosphate + UDP-alpha-D-glucuronate. GO:0106130 purine phosphoribosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106130 Catalysis of the reaction: RMP + diphosphate = R + 5-phospho-alpha-D-ribose 1-diphosphate. GO:0106137 IkappaB kinase complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106137 Interacting selectively and non-covalently with the IkappaB kinase complex. GO:0106136 lectin-induced modified bacterial internalization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106136 LIMBI The process in which an organism effects a change in the structure or function of a symbiont organism, mediated by secretion of lectins which bind to the bacterial surface. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0106135 negative regulation of cardiac muscle cell contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106135 Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell contraction. UBERON:0036352 wall of subclavian artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036352 subclavian arterial wall GO:0106134 positive regulation of cardiac muscle cell contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106134 Any process that activates or increases the frequency, rate or extent of cardiac muscle cell contraction. UBERON:0036351 wall of brachiocephalic artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036351 brachiocephalic arterial wall CHEBI:15908 L-threonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15908 CHEBI:15907 phosphoramidic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15907 GO:0106139 symbiont cell surface biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0106139 endosymbiont cell surface The cell surface of a secondary, endosymbiont organism with which the first organism is interacting. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0047359 1-alkenyl-2-acylglycerol choline phosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047359 MetaCyc:2.7.8.22-RXN|EC:2.7.8.22|RHEA:21072 CDP-choline:1-alkenyl-2-acylglycerol cholinephosphotransferase activity|CDP-choline-1-alkenyl-2-acyl-glycerol phosphocholinetransferase activity Catalysis of the reaction: 1-alkenyl-2-acylglycerol + CDP-choline = plasmenylcholine + CMP. GO:0047358 UDP-glucose-glycoprotein glucose phosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047358 EC:2.7.8.19|RHEA:20181|MetaCyc:2.7.8.19-RXN GlcPTase activity|UDPglucose-glycoprotein glucose phosphotransferase activity|Glc-phosphotransferase activity|UDPglucose:glycoprotein-D-mannose glucosephosphotransferase activity|uridine diphosphoglucose-glycoprotein glucose-1-phosphotransferase activity|UDP-glucose:glycoprotein glucose-1-phosphotransferase activity|UDP-glucose:glycoprotein-D-mannose glucosephosphotransferase activity Catalysis of the reaction: glycoprotein D-mannose + UDP-D-glucose = glycoprotein 6-(D-glucose-1-phospho)-D-mannose + UMP. GO:0106138 Sec61 translocon complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106138 Interacting selectively and non-covalently with a Sec61 translocon complex. GO:0047357 UDP-galactose-UDP-N-acetylglucosamine galactose phosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047357 MetaCyc:2.7.8.18-RXN|KEGG_REACTION:R00504|EC:2.7.8.18|RHEA:22440 galactose-1-phosphotransferase activity|galactosyl phosphotransferase activity|UDPgalactose:UDP-N-acetyl-D-glucosamine galactose phosphotransferase activity|UDPgalactose-UDP-N-acetylglucosamine galactose phosphotransferase activity|uridine diphosphogalactose-uridine diphosphoacetylglucosamine galactose-1-phosphotransferase activity|UDP-galactose:UDP-N-acetyl-D-glucosamine galactose phosphotransferase activity Catalysis of the reaction: UDP-N-acetyl-alpha-D-glucosamine + UDP-D-galactose = H(+) + UDP-N-acetyl-6-(D-galactose-1-phospho)-D-glucosamine + UMP. CHEBI:15904 long-chain fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15904 GO:0047356 CDP-ribitol ribitolphosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047356 MetaCyc:2.7.8.14-RXN|EC:2.7.8.14|RHEA:13353 teichoate synthase activity|teichoic-acid synthase activity|polyribitol phosphate polymerase activity|polyribitol phosphate synthetase activity|CDPribitol ribitolphosphotransferase activity|teichoate synthetase activity|CDP-ribitol:poly(ribitol phosphate) ribitolphosphotransferase activity|poly(ribitol phosphate) synthetase activity Catalysis of the reaction: ribitol phosphate(n) + CDP-ribitol = ribitol phosphate(n+1) + CMP. CHEBI:15903 beta-D-glucose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15903 GO:0047355 CDP-glycerol glycerophosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047355 MetaCyc:2.7.8.12-RXN|RHEA:13565|EC:2.7.8.12 glycerophosphate synthetase activity|teichoic-acid synthase activity|CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase activity|CDPglycerol glycerophosphotransferase activity|CGPTase activity|poly(glycerol phosphate) polymerase activity|teichoic acid glycerol transferase activity|cytidine diphosphoglycerol glycerophosphotransferase activity Catalysis of the reaction: glycerophosphate(n) + CDP-glycerol = glycerophosphate(n+1) + CMP. CHEBI:15906 demethylmacrocin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15906 GO:0047354 sphingosine cholinephosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047354 KEGG_REACTION:R01929|MetaCyc:2.7.8.10-RXN|RHEA:21224|EC:2.7.8.10 CDP-choline-sphingosine cholinephosphotransferase activity|cytidine diphosphocholine-sphingosine cholinephosphotransferase activity|sphingosine choline phosphotransferase activity|phosphorylcholine-sphingosine transferase activity|CDP-choline:sphingosine cholinephosphotransferase activity Catalysis of the reaction: CDP-choline + sphingosine = CMP + H(+) + sphingosyl-phosphocholine. CHEBI:15905 (R)-4'-phosphopantothenic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15905 CL:1000279 smooth muscle cell of large intestine biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000279 non-striated muscle fiber of large intestine A smooth muscle cell that is part of the large intestine. CHEBI:15900 trans-2,3-epoxysuccinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15900 CHEBI:15902 alpha-D-xylose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15902 CHEBI:15901 5,6-dihydrouracil biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15901 CHEBI:74280 (R)-3-hydroxyhexanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74280 CL:1000275 smooth muscle cell of small intestine biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000275 non-striated muscle fiber of small intestine A smooth muscle cell that is part of the small intestine. CL:1000274 trophectodermal cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000274 trophectoderm cell GO:0072319 vesicle uncoating biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072319 vesicle coat disassembly A protein depolymerization process that results in the disassembly of vesicle coat proteins. CHEBI:74282 (11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74282 CL:1000272 lung secretory cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000272 GO:0072318 clathrin coat disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072318 clathrin-coated vesicle uncoating|clathrin-coat disassembly|clathrin-coat uncoating The disaggregation of a clathrin coat into its constituent components; results in stripping or removing the clathrin coat from clathrin-coated vesicles (CCV) before fusing with their targets. CVVs transport cargo from plasma membrane and trans-Golgi to the endosomal system. CHEBI:74281 trans-2-hexacosenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74281 GO:0072317 obsolete glucan endo-1,3-beta-D-glucosidase activity involved in ascospore release from ascus biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0072317 OBSOLETE. Catalysis of the hydrolysis of 1,3-beta-D-glucosidic linkages in 1,3-beta-D-glucans that contributes to the release of ascospores from the ascus. CL:1000271 lung ciliated cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000271 GO:0072316 alpha-glucan catabolic process involved in ascospore release from ascus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072316 alpha-glucan catabolism involved in ascospore release from ascus|alpha-glucan breakdown involved in ascospore release from ascus|alpha-glucan degradation involved in ascospore release from ascus The chemical reactions and pathways resulting in the breakdown of alpha-glucans in the ascus wall that contributes to the release of ascospores from the ascus. CHEBI:74283 (13Z,16Z,19Z,22Z)-3-oxooctacosatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74283 GO:0072315 metanephric glomerular epithelial cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072315 The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular epithelial cell. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells. CHEBI:74286 (15Z,18Z,21Z,24Z)-3-oxotriacontatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74286 GO:0072314 glomerular epithelial cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072314 The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular epithelial cell. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells. CHEBI:74285 (13Z,16Z,19Z,22Z)-octacosatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74285 GO:0106140 P-TEFb complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106140 Interacting selectively and non-covalently with the P-TEFb complex. CHEBI:74288 (17Z,20Z,23Z,26Z)-3-oxodotriacontatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74288 GO:0072313 metanephric glomerular epithelial cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072313 The process whose specific outcome is the progression of a metanephric glomerular epithelial cell over time, from its formation to the mature structure. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells. GO:0072312 metanephric glomerular epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072312 The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular epithelial cell. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells. CHEBI:74287 (15Z,18Z,21Z,24Z)-triacontatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74287 GO:0072311 glomerular epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072311 The process in which a relatively unspecialized cell acquires specialized features of a glomerular epithelial cell. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells. CHEBI:74289 (17Z,20Z,23Z,26Z)-dotriacontatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74289 GO:0072310 glomerular epithelial cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072310 The process whose specific outcome is the progression of a glomerular epithelial cell over time, from its formation to the mature structure. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells. GO:0047364 desulfoglucosinolate sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047364 RHEA:20281|MetaCyc:2.8.2.24-RXN|KEGG_REACTION:R03214|EC:2.8.2.24 desulphoglucosinolate sulphotransferase activity|3'-phosphoadenosine-5'-phosphosulfate:desulfoglucosinolate sulfotransferase activity|3'-phosphoadenylyl-sulfate:desulfoglucosinolate sulfotransferase activity|PAPS-desulfoglucosinolate sulfotransferase activity Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + desulfoglucotropeolin = adenosine 3',5'-diphosphate + glucotropeolin + H(+). GO:0106144 fraxetin 5-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106144 EC:1.14.14.164|RHEA:57844 Catalyzes the reaction fraxetin+ NAD(P)H + 02= sideretin + NAD(P)(+) + H20. GO:0106143 tRNA (m7G46) methyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0106143 Trm8-Trm82 complex|tRNA m7G methylation complex|tRNA (m7G46) methyltransferase A protein complex involved in the catalysis of the formation of the modified nucleotide 7-methylguanine (at position 46 in certain tRNAs, such as tRNA(phe) and tRNA(met). In yeast, it is a heterotetramer of two subunits, Trm8 (catalytic) and Trm82 (WD repeat). GO:0047363 triglucosylalkylacylglycerol sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047363 RHEA:13273|MetaCyc:2.8.2.19-RXN|EC:2.8.2.19 triglucosylalkylacylglycerol sulphotransferase activity|triglucosylmonoalkylmonoacyl sulfotransferase activity|3'-phosphoadenylyl-sulfate:triglucosyl-1-O-alkyl-2-O-acylglycerol 6-sulfotransferase activity Catalysis of the reaction: alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol + 3'-phosphoadenosine 5'-phosphosulfate = 6-sulfo-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol + adenosine 3',5'-bisphosphate. GO:0106142 rRNA (adenine-N1-)-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106142 RHEA:43792|EC:2.1.1.287 25S rRNA (adenine(645)-N(1))-methyltransferase|25S rRNA m(1)A(645) methyltransferase Catalysis of the reaction: S-adenosyl-L-methionine + adenine(645) in 25S rRNA = S-adenosyl-L-homocysteine + N(1)-methyladenine(645) in 25S rRNA. GO:0047362 thiosulfate-dithiol sulfurtransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047362 RHEA:15121|MetaCyc:2.8.1.5-RXN|EC:2.8.1.5 thiosulfate reductase activity|TSR|thiosulphate-dithiol sulphurtransferase activity|thiosulfate:dithioerythritol sulfurtransferase activity Catalysis of the reaction: dithioerythritol + thiosulfate = hydrogen sulfide + dithioerythritol disulfide + sulfite. GO:0106141 flavin prenyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106141 EC:2.5.1.129|RHEA:37743 Catalysis of the reaction: dimethylallylphosphate + FMNH2 = prenylated FMNH2 + phosphate. GO:0047361 phosphomannan mannosephosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047361 MetaCyc:2.7.8.9-RXN|EC:2.7.8.9 GDP-mannose:phosphomannan mannose phosphotransferase activity Catalysis of the reaction: phosphomannan(n) + GDP-mannose = phosphomannan(n+1) + GMP. GO:0047360 undecaprenyl-phosphate galactose phosphotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047360 MetaCyc:2.7.8.6-RXN|EC:2.7.8.6|KEGG_REACTION:R01535|RHEA:11652 poly(isoprenol)-phosphate galactose phosphotransferase activity|poly(isoprenyl)phosphate galactosephosphatetransferase activity|poly(isoprenol)-phosphate galactosephosphotransferase activity|undecaprenyl phosphate galactosyl-1-phosphate transferase activity|UDP-galactose:undecaprenyl-phosphate galactose phosphotransferase activity Catalysis of the reaction: all-trans-undecaprenyl phosphate + UDP-D-galactose = alpha-D-galactosyl-diphosphoundecaprenol + UMP. GO:0106148 4-hydroxyindole-3- carbonyl nitrile biosynthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106148 The chemical reactions and pathways resulting in the formation of 4-hydroxyindole-3- carbonyl nitrile (4-OH-ICN), a cyanogenic glucoside. GO:0106147 fraxetin biosynthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106147 The chemical reactions and pathways resulting in the formation of fraxetin. GO:0106146 sideretin biosynthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106146 The chemical reactions and pathways resulting in the formation of sideretin. UBERON:0036362 wall of anal canal biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036362 anal canal wall GO:0106145 scopoletin 8-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106145 EC:1.14.11.60|RHEA:57848 Catalyzes of the reaction: scopoletin + 2-oxoglutarate+O2=fraxetin +succinate+ CO2). GO:0047369 succinate-hydroxymethylglutarate CoA-transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047369 EC:2.8.3.13|RHEA:12284|MetaCyc:2.8.3.13-RXN dicarboxyl-CoA:dicarboxylic acid coenzyme A transferase activity|hydroxymethylglutarate coenzyme A-transferase activity|succinate:(S)-3-hydroxy-3-methylglutarate CoA-transferase activity Catalysis of the reaction: (S)-3-hydroxy-3-methylglutarate + succinyl-CoA = 3-hydroxy-3-methyl-glutaryl-CoA + succinate. GO:0106149 indole-3-carbonyl nitrile 4-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106149 EC:1.14.14.165|RHEA:57864 Catalysis of the reaction: indole-3-carbonyl nitrile + NADPH +O2=4-hydroxyindole-3- carbonyl nitrile + NADP(+) + H20. GO:0047368 UDP-N-acetylgalactosamine-4-sulfate sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047368 KEGG_REACTION:R04476|MetaCyc:2.8.2.7-RXN|EC:2.8.2.7|RHEA:14337 uridine diphosphoacetylgalactosamine 4-sulfate sulfotransferase activity|UDP-N-acetylgalactosamine-4-sulphate sulphotransferase activity|3'-phosphoadenylyl-sulfate:UDP-N-acetyl-D-galactosamine-4-sulfate 6-sulfotransferase activity|uridine diphospho-N-acetylgalactosamine 4-sulfate sulfotransferase activity Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + UDP-N-acetyl-D-galactosamine 4-sulfate = adenosine 3',5'-diphosphate + H(+) + UDP-N-acetyl-D-galactosamine 4,6-disulfate. GO:0047367 quercetin-3,3'-bissulfate 7-sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047367 RHEA:21860|MetaCyc:2.8.2.28-RXN|EC:2.8.2.28 quercetin-3,3'-bissulphate 7-sulphotransferase activity|3'-phosphoadenylyl-sulfate:quercetin-3,3'-bissulfate 7-sulfotransferase activity|7-sulfotransferase activity|flavonol 7-sulfotransferase activity|PAPS:flavonol 3,3'/3,4'-disulfate 7-sulfotransferase activity Catalysis of the reaction: quercetin 3,3'-bissulfate + 3'-phosphoadenosine 5'-phosphosulfate = quercetin 3,3',7-trissulfate + adenosine 3',5'-bisphosphate. GO:0047366 quercetin-3-sulfate 4'-sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047366 RHEA:17205|MetaCyc:2.8.2.27-RXN|EC:2.8.2.27|KEGG_REACTION:R02633 flavonol 4'-sulfotransferase activity|3'-phosphoadenylyl-sulfate:quercetin-3-sulfate 4'-sulfotransferase activity|PAPS:flavonol 3-sulfate 4'-sulfotransferase activity|quercetin-3-sulphate 4'-sulphotransferase activity Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + quercetin 3-sulfate = adenosine 3',5'-diphosphate + H(+) + quercetin 3,4'-disulfate. GO:0047365 quercetin-3-sulfate 3'-sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0047365 MetaCyc:2.8.2.26-RXN|RHEA:22504|EC:2.8.2.26|KEGG_REACTION:R02632 flavonol 3'-sulfotransferase activity|3'-phosphoadenylyl-sulfate:quercetin-3-sulfate 3'-sulfotransferase activity|PAPS:flavonol 3-sulfate 3'-sulfotransferase activity|3'-sulfotransferase activity|quercetin-3-sulphate 3'-sulphotransferase activity Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + quercetin 3-sulfate = adenosine 3',5'-diphosphate + H(+) + quercetin 3,3'-disulfate. CL:0002454 Cd4-negative, CD8_alpha-negative, CD11b-positive dendritic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002454 DC.8-4-11b+|spleen double-negative dendritic cell Cd4-negative, CD8_alpha-negative, CD11b-positive dendritic cell is a conventional dendritic cell that is CD11b-positive, CD4-negative, CD8_alpha-negative and is CD205-positive. CL:0002453 oligodendrocyte precursor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002453 The cell type from which oligodendrocytes develop. This cell originates from multiple structures within the developing brain including the medial ganglion eminence and the lateral ganglionic eminence. These cells migrate throughout the central nervous system and persist into adulthood where they play an important role in remyelination of injured neurons. CL:0002456 CD8_alpha-positive plasmactyoid dendritic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002456 DC.pDC.8+ A CD11c-low plasmacytoid dendritic cell that is CD8alpha-positive and CD4-positive. CHEBI:74291 (19Z,22Z,25Z,28Z)-tetratriacontatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74291 CL:0002455 CD8_alpha-negative plasmactyoid dendritic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002455 DC.pDC.8- A CD11c-low plasmacytoid dendritic cell that is CD8alpha-negative and CD4-positive. CHEBI:74290 (19Z,22Z,25Z,28Z)-3-oxotetratriacontatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74290 GO:0072309 mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072309 The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the metanephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells. GO:0072308 negative regulation of metanephric nephron tubule epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072308 Any process that decreases the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation. CHEBI:74293 (21Z,24Z,27Z,30Z)-hexatriacontatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74293 CL:0002457 epidermal Langerhans cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002457 A Langerhans cell that is in the epidermis and is CD45-positive, MHCII-positive, and CD11b-positive. CHEBI:74292 (21Z,24Z,27Z,30Z)-3-oxohexatriacontatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74292 GO:0072307 regulation of metanephric nephron tubule epithelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072307 Any process that modulates the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation. GO:0072306 positive regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072306 positive regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis|positive regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros. GO:0072305 negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072305 negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis|negative regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros. CHEBI:74294 (23Z,26Z,29Z,32Z)-3-oxooctatriacontatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74294 GO:0072304 regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072304 regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis|regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros. CHEBI:74297 (9Z,11E)-octadecadienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74297 GO:0072303 positive regulation of glomerular metanephric mesangial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072303 Any process that increases the frequency, rate or extent of metanephric glomerular mesangial cell proliferation. CHEBI:74296 (11E)-octadecenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74296 GO:0072302 negative regulation of metanephric glomerular mesangial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072302 Any process that decreases the frequency, rate or extent of metanephric glomerular mesangial cell proliferation. CHEBI:74299 geranyllinalool biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74299 GO:0106151 CNBH domain intrinsic ligand binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0106151 Interacting selectivity and noncovalently with a cyclic nucleotide mimicking protein motif that is part of the same protein. The CNBHD is a domain on KCNH channels that creates a binding pocket on the KCNH channel that resembles the cyclic nucleotide- binding domain on other ion channels. It binds to a peptide motif that is part of the same protein rather than a cyclic nucleotide. GO:0106150 zearalenone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0106150 The chemical reactions and pathways resulting in the formation of zearalenone, a mycotoxin produced by several Fusarium species, is most commonly found as a contaminant in stored grain and has chronic estrogenic effects on mammals. GO:0072301 regulation of metanephric glomerular mesangial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072301 Any process that modulates the frequency, rate or extent of metanephric glomerular mesangial cell proliferation. CHEBI:74298 (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74298 GO:0072300 positive regulation of metanephric glomerulus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0072300 Any process that increases the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros. OBO:GOCHE_33290 substance with food role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_33290 GO:0052049 obsolete interaction with host via protein secreted by type III secretion system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052049 OBSOLETE. An interaction with the host organism mediated by a substance secreted by the symbiont organism by a type III secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052048 obsolete interaction with host via secreted substance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052048 interaction with host via secreted substance during symbiotic interaction|interaction with host via secreted substance involved in symbiotic interaction OBSOLETE. An interaction with the host organism mediated by a substance secreted by the other (symbiont) organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052043 modification by symbiont of host cellular component biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052043 The process in which an organism effects a change in the structure or function of a host cellular component. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052042 positive regulation by symbiont of host programmed cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052042 activation by organism of host programmed cell death|induction by symbiont of host programmed cell death|activation by organism of programmed cell death in other organism during symbiotic interaction|stimulation by symbiont of host programmed cell death|induction of non-apoptotic programmed cell death by other organism|enhancement of host programmed cell death|induction by organism of programmed cell death in other organism during symbiotic interaction|activation by symbiont of host programmed cell death|positive regulation by symbiont of host non-apoptotic programmed cell death|enhancement of host programmed cell death by organism|induction by organism of programmed cell death in other organism involved in symbiotic interaction|induction by organism of non-apoptotic programmed cell death in other organism during symbiotic interaction|activation by organism of non-apoptotic programmed cell death in other organism|upregulation by symbiont of host programmed cell death Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052041 negative regulation by symbiont of host programmed cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052041 suppression by symbiont of host PCD|down-regulation by symbiont of host programmed cell death|suppression by symbiont of host programmed cell death|inhibition of host programmed cell death|downregulation by symbiont of host programmed cell death|down regulation by symbiont of host programmed cell death|inhibition by symbiont of host programmed cell death Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052040 modulation by symbiont of host programmed cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052040 modulation of host PCD|modulation by symbiont of host non-apoptotic programmed cell death Any process in which an organism modulates the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052047 obsolete symbiotic process mediated by secreted substance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052047 interaction with other organism via secreted substance during symbiotic interaction|interaction with other organism via secreted substance involved in symbiotic interaction OBSOLETE. An interaction with a second organism mediated by a substance secreted by the first organism, where the two organisms are in a symbiotic interaction. GO:0052046 obsolete modification by symbiont of host morphology or physiology via secreted substance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052046 modification of host morphology or physiology via effector molecule|modification of host morphology or physiology via ellicitor OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by one of the organisms. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052045 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052045 GO:0052044 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052044 GO:0052059 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052059 GO:0052050 obsolete interaction with host via substance secreted by type IV secretion system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052050 OBSOLETE. An interaction with the host organism mediated by a substance secreted by the other organism by a type IV secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052054 negative regulation by symbiont of host peptidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052054 negative regulation by symbiont of host protease activity|down-regulation by symbiont of host protease activity|inhibition of host protease activity|downregulation by symbiont of host protease activity|down regulation by symbiont of host protease activity|inhibition by symbiont of host protease activity Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of host protease activity, the catalysis of the hydrolysis of peptide bonds in a protein. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052053 negative regulation by symbiont of host catalytic activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052053 downregulation by symbiont of host enzyme activity|down regulation by symbiont of host enzyme activity|inhibition by symbiont of host enzyme activity|negative regulation by symbiont of host enzyme activity|down-regulation by symbiont of host enzyme activity|inhibition of host enzyme activity Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of host enzyme activity. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052052 obsolete modification by symbiont of host morphology or physiology via protein secreted by type II secretion system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052052 OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type II secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052051 obsolete interaction with host via protein secreted by type II secretion system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052051 OBSOLETE. An interaction with the host organism mediated by a substance secreted by the other organism by a type II secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052058 obsolete modification by symbiont of host morphology or physiology via substance secreted by type IV secretion system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052058 OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type IV secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052057 obsolete modification by symbiont of host morphology or physiology via protein secreted by type III secretion system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052057 OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type III secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052056 negative regulation by symbiont of host molecular function biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052056 down-regulation by symbiont of host protein function|inhibition by symbiont of host protein function|down regulation by symbiont of host protein function|negative regulation by symbiont of host protein function|downregulation by symbiont of host protein function|inhibition of host protein function Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the functional activity of host proteins. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052055 modulation by symbiont of host molecular function biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052055 modification by symbiont of host molecular function|modification by symbiont of host protein function The process in which an organism effects a change in the function of a host protein via a direct interaction. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0003098 tubuloglomerular feedback biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003098 Wikipedia:Tubuloglomerular_feedback The process in which blood volume is regulated due to a change in the rate of glomerular filtration. This is accomplished by a feedback mechanism that senses changes in the juxtaglomerular apparatus. GO:0003097 renal water transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003097 The directed movement of water (H2O) by the renal system. GO:0003099 positive regulation of the force of heart contraction by chemical signal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003099 positive regulation of the force of heart muscle contraction by chemical signal Any process which increases the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine. GO:0003094 glomerular filtration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003094 The process in which plasma is filtered through the glomerular membrane which consists of capillary endothelial cells, the basement membrane, and epithelial cells. The glomerular filtrate is the same as plasma except it has no significant amount of protein. GO:0003093 regulation of glomerular filtration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003093 Any process that modulates the frequency, rate or extent of glomerular filtration. Glomerular filtration is the process in which blood is filtered by the glomerulus into the renal tubule. GO:0003096 renal sodium ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003096 The directed movement of sodium ions (Na+) by the renal system. GO:0003095 pressure natriuresis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003095 The process in which the volume of blood increases renal pressure and thereby results in both an increase in urine volume (diuresis) and an increase in the amount of sodium excreted in the urine (natriuresis). GO:0052061 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052061 GO:0052060 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052060 GO:0052065 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052065 GO:0052064 induction by symbiont of defense-related host reactive oxygen species production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052064 activation by symbiont of defense-related host metabolic burst|induction by organism of defense-related reactive oxygen species production in other organism involved in symbiotic interaction|activation by symbiont of defense-related host ROS production|upregulation by symbiont of defense-related host reactive oxygen species production|induction by symbiont of defense-related host reactive oxidative species production|induction by symbiont of defense-related host oxidative burst|activation by symbiont of defense-related host respiratory burst|induction by symbiont of defense-related reactive oxygen species production in other organism involved in symbiotic interaction|activation by symbiont of defense-related host reactive oxygen intermediate production|induction by symbiont of defense-related host active oxygen species production|up regulation by symbiont of defense-related host reactive oxygen species production|positive regulation by symbiont of defense-related host reactive oxygen species production|activation by symbiont of defense-related host reactive oxygen species production|activation by symbiont of defense-related host reactive oxidative species production|positive regulation by organism of defense-related reactive oxygen species production in other organism involved in symbiotic interaction|activation by symbiont of defense-related host oxidative burst|induction by symbiont of defense-related host metabolic burst|stimulation by symbiont of defense-related host reactive oxygen species production|activation by symbiont of defense-related host ROI production|up-regulation by symbiont of defense-related host reactive oxygen species production|induction by symbiont of defense-related host AOS production The activation by a symbiont of the production of reactive oxygen species as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052063 induction by symbiont of defense-related host nitric oxide production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052063 activation by organism of defense-related host nitric oxide production|upregulation by symbiont of defense-related host nitric oxide production|induction by organism of defense-related host NO production|up-regulation by symbiont of defense-related host nitric oxide production|positive regulation by organism of defense-related nitric oxide production in other organism involved in symbiotic interaction|activation by organism of defense-related host NO production|stimulation by symbiont of defense-related host nitric oxide production|activation by symbiont of defense-related host nitric oxide production|positive regulation by symbiont of defense-related host nitric oxide production|induction by organism of defense-related nitric oxide production in other organism involved in symbiotic interaction|positive regulation by organism of defense-related host NO production|up regulation by symbiont of defense-related host nitric oxide production The activation by a symbiont of the production of nitric oxide as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052062 induction by symbiont of host phytoalexin production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052062 induction by organism of phytoalexin production in other organism involved in symbiotic interaction|activation by organism of host phytoalexin production The activation by a symbiont of the production of phytoalexins as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052069 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052069 GO:0052068 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052068 GO:0052067 antiphagocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052067 modulation by organism of entry into host via host phagocytosis|down regulation by symbiont of entry into host cell via phagocytosis|negative regulation by organism of entry into cell of other organism via phagocytosis involved in symbiotic interaction|negative regulation by organism of entry into host cell via host phagocytosis|modulation by symbiont of entry into host via phagocytosis|downregulation by symbiont of entry into host cell via phagocytosis|phagocytosis avoidence|down-regulation by symbiont of entry into host cell via phagocytosis|negative regulation by symbiont of entry into host cell via phagocytosis|inhibition by symbiont of entry into host cell via phagocytosis Any process in which a symbiont avoids phagocytosis by a host cell, for example a phagocyte or a macrophage. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052066 obsolete entry of symbiont into host cell by promotion of host phagocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052066 penetration of symbiont into host cell by promotion of host phagocytosis|entry of organism into cell of other organism by promotion of phagocytosis in other organism during symbiotic interaction|entry of organism into host cell by promotion of host phagocytosis|entry of organism into cell of other organism by promotion of phagocytosis in other organism involved in symbiotic interaction|penetration of organism into host cell by promotion of host phagocytosis OBSOLETE. The invasion by a symbiont of a host organism cell by utilizing the host phagocytosis mechanism. The host is defined as the larger of the organisms involved in a symbiotic interaction. RO:0000081 role of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0000081 RO:0000081 a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence RO:0000087 has role biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0000087 RO:0000087 a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence RO:0000086 has quality biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0000086 RO:0000086 GO:0052072 induction by symbiont of defense-related host salicylic acid-mediated signal transduction pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052072 positive regulation by organism of defense-related salicylic acid-mediated signal transduction pathway in other organism involved in symbiotic interaction|induction by organism of defense-related host salicylic acid-mediated signal transduction pathway|positive regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|activation by organism of defense-related host SA-mediated signal transduction pathway|up regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|positive regulation by organism of defense-related host SA-mediated signal transduction pathway|activation by organism of defense-related host salicylic acid-mediated signal transduction pathway|upregulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|upregulation by organism of defense-related host SA-mediated signal transduction pathway|stimulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|up-regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|induction by organism of defense-related host SA-mediated signal transduction pathway|activation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|upregulation by organism of defense-related host salicylic acid-mediated signal transduction pathway Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of host salicylic acid-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052071 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052071 GO:0052070 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052070 GO:0052076 induction by symbiont of host ethylene-mediated defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052076 up-regulation by symbiont of host ethylene-mediated defense response|positive regulation by symbiont of defense-related host ethylene-mediated signal transduction pathway|upregulation by symbiont of host ethylene-mediated defense response|positive regulation by organism of ethylene-mediated defense response of other organism involved in symbiotic interaction|up regulation by symbiont of host ethylene-mediated defense response|positive regulation by organism of defense-related ethylene-mediated signal transduction pathway in other organism involved in symbiotic interaction|activation by symbiont of host ethylene-mediated defense response|positive regulation by symbiont of host ethylene-mediated defense response|stimulation by symbiont of host ethylene-mediated defense response Any process in which an organism activates, maintains or increases the frequency, rate or extent of the ethylene-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052075 positive regulation by symbiont of host jasmonic acid-mediated defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052075 stimulation by symbiont of host jasmonic acid-mediated defense response|up-regulation by symbiont of host jasmonic acid-mediated defense response|activation by symbiont of host jasmonic acid-mediated defense response|induction by organism of host JA-mediated defense response|induction by organism of host jasmonic acid-mediated defense response|up regulation by symbiont of host jasmonic acid-mediated defense response|positive regulation by organism of jasmonic acid-mediated defense response of other organism involved in symbiotic interaction|positive regulation by organism of host JA-mediated defense response|upregulation by symbiont of host jasmonic acid-mediated defense response Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of the jasmonic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052074 positive regulation by symbiont of host salicylic acid-mediated defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052074 upregulation by symbiont of host salicylic acid-mediated defense response|induction by organism of host salicylic acid-mediated defense response|positive regulation by organism of host SA-mediated defense response|positive regulation by organism of salicylic acid-mediated defense response of other organism involved in symbiotic interaction|up regulation by symbiont of host salicylic acid-mediated defense response|activation by symbiont of host salicylic acid-mediated defense response|induction by organism of host SA-mediated defense response|stimulation by symbiont of host salicylic acid-mediated defense response|up-regulation by symbiont of host salicylic acid-mediated defense response Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of the salicylic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052073 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052073 GO:0052079 induction by symbiont of defense-related host MAP kinase-mediated signal transduction pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052079 activation by organism of defense-related host MAP kinase-mediated signal transduction pathway|upregulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|positive regulation by organism of defense-related host mitogen-activated protein kinase-mediated signal transduction pathway|stimulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|activation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|up-regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|upregulation by organism of defense-related host MAP kinase-mediated signal transduction pathway|positive regulation by organism of defense-related MAP kinase-mediated signal transduction pathway in other organism involved in symbiotic interaction|positive regulation by organism of defense-related host MAPK-mediated signal transduction pathway|induction by organism of defense-related host MAP kinase-mediated signal transduction pathway|positive regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|up regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway Any process in which an organism activates, maintains or increases the frequency, rate or extent of a host MAP kinase-mediated signal transduction pathway during the host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052078 suppression by symbiont of defense-related host MAP kinase-mediated signal transduction pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052078 inhibition by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|negative regulation by organism of defense-related host mitogen-activated protein kinase-mediated signal transduction pathway|suppression by organism of defense-related host MAP kinase-mediated signal transduction pathway|negative regulation by organism of defense-related host MAPK-mediated signal transduction pathway|negative regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|down-regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|negative regulation by organism of defense-related MAP kinase-mediated signal transduction pathway in other organism involved in symbiotic interaction|downregulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|down regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of a host MAP kinase-mediated signal transduction pathway during the host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052077 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052077 GO:0003079 obsolete positive regulation of natriuresis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003079 positive regulation of natriuresis OBSOLETE. Any process that activates or increases the frequency, rate or extent of natriuresis. GO:0003076 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003076 GO:0003075 renal vasodilation of the peripheral vascular system involved in regulation of systemic arterial blood pressure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003075 renal regulation of systemic arterial blood pressure by vasodilation of the peripheral vascular system The renal process that modulates the force with which blood travels through the circulatory system, by vasodilation of the peripheral vascular system. GO:0003078 obsolete regulation of natriuresis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003078 regulation of natriuresis OBSOLETE. Any process that modulates the frequency, rate, or extent of natriuresis, the process of renal sodium excretion. GO:0003077 obsolete negative regulation of diuresis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003077 negative regulation of diuresis OBSOLETE. Any process that reduces the rate of diuresis. Diuresis is the process of renal water excretion. GO:0003072 renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003072 regulation of systemic arterial blood pressure by renal control of peripheral vascular resistence|renal regulation of systemic arterial blood pressure by control of peripheral vascular resistence The renal process that modulates the force with which blood travels through the circulatory system, by impeding blood flow through the peripheral vasculature. GO:0003071 renal system process involved in regulation of systemic arterial blood pressure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003071 renal control of blood pressure|renal regulation of systemic arterial blood pressure Renal process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure. GO:0003074 obsolete regulation of diuresis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003074 regulation of diuresis OBSOLETE. Any process that modulates the rate of diuresis. Diuresis is the process of renal water excretion. GO:0003073 regulation of systemic arterial blood pressure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003073 The process that modulates the force with which blood travels through the systemic arterial circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure. GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003081 blood pressure regulation by renin-angiotensin The process in which renin-angiotensin modulates the force with which blood passes through the circulatory system. GO:0003080 obsolete negative regulation of natriuresis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003080 negative regulation of natriuresis OBSOLETE. Any process that stops, prevents, or decreases the frequency, rate, or extent of natriuresis, the process of renal sodium excretion. GO:0052083 suppression by symbiont of host cell-mediated immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052083 negative regulation by organism of host cell-based immune response|downregulation by symbiont of host cell-mediated immune response|down regulation by symbiont of host cell-mediated immune response|inhibition by symbiont of host cell-mediated immune response|negative regulation by organism of cell-mediated immune response of other organism involved in symbiotic interaction|down-regulation by symbiont of host cell-mediated immune response Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052082 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052082 GO:0052081 modulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052081 modulation of defense-related host SA-mediated signal transduction pathway by organism|modulation by organism of defense-related salicylic acid-mediated signal transduction pathway in other organism involved in symbiotic interaction Any process in which an organism modulates the frequency, rate or extent of host salicylic acid-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052080 modulation by symbiont of host innate immune response MAPK kinase signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052080 modulation by organism of defense-related MAP kinase-mediated signal transduction pathway in other organism involved in symbiotic interaction|modulation of defense-related host MAPK-mediated signal transduction pathway by organism|modulation of defense-related host mitogen activated protein kinase-mediated signal transduction pathway by organism|modulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway Any process in which an organism modulates the frequency, rate or extent of a host MAP kinase-mediated signal transduction pathway during the host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052087 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052087 GO:0052086 suppression by symbiont of host B-cell mediated immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052086 down regulation by symbiont of host B-cell mediated immune response|inhibition by symbiont of host B-cell mediated immune response|negative regulation by organism of B-cell mediated immune response of other organism involved in symbiotic interaction|down-regulation by symbiont of host B-cell mediated immune response|downregulation by symbiont of host B-cell mediated immune response Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the B-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052085 suppression by symbiont of host T-cell mediated immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052085 negative regulation by symbiont of host T-cell mediated immune response|down-regulation by symbiont of host T-cell mediated immune response|downregulation by symbiont of host T-cell mediated immune response|down regulation by symbiont of host T-cell mediated immune response|inhibition by symbiont of host T-cell mediated immune response|negative regulation by organism of T-cell mediated immune response of other organism involved in symbiotic interaction Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the T-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:4031 cyclosporin A biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_4031 GO:0052084 modulation by symbiont of host ethylene-mediated defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052084 modulation by symbiont of defense-related host ethylene-mediated signal transduction pathway|modulation by organism of defense-related ethylene-mediated signal transduction pathway in other organism involved in symbiotic interaction|modulation by organism of ethylene-mediated defense response of other organism involved in symbiotic interaction Any process in which a symbiont modulates the frequency, rate or extent of the ethylene-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052089 modulation by symbiont of host salicylic acid-mediated defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052089 modulation by organism of host SA-mediated defense response|modulation by organism of salicylic acid-mediated defense response of other organism involved in symbiotic interaction Any process in which a symbiont modulates the frequency, rate or extent of the salicylic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052088 symbiont defense to host-produced jasmonic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052088 negative regulation by organism of jasmonic acid-mediated defense response of other organism involved in symbiotic interaction|activation by organism of defense-related host jasmonic acid-mediated signal transduction pathway|induction by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway|modulation by organism of defense-related jasmonic acid-mediated signal transduction pathway in other organism involved in symbiotic interaction|downregulation by symbiont of host jasmonic acid-mediated defense response|suppression by symbiont of host jasmonic acid-mediated defense response|upregulation by organism of defense-related host SA-mediated signal transduction pathway|upregulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway|down regulation by symbiont of host jasmonic acid-mediated defense response|modulation by organism of jasmonic acid-mediated defense response of other organism involved in symbiotic interaction|negative regulation by organism of defense-related jasmonic acid-mediated signal transduction pathway in other organism involved in symbiotic interaction|induction by organism of defense-related host SA-mediated signal transduction pathway|induction by organism of defense-related host jasmonic acid-mediated signal transduction pathway|inhibition by symbiont of host jasmonic acid-mediated defense response|positive regulation by organism of defense-related jasmonic acid-mediated signal transduction pathway in other organism involved in symbiotic interaction|suppression by organism of host JA-mediated defense response|up regulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway|upregulation by organism of defense-related host jasmonic acid-mediated signal transduction pathway|positive regulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway|modulation by organism of host JA-mediated defense response|activation by organism of defense-related host SA-mediated signal transduction pathway|negative regulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway|activation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway|down-regulation by symbiont of host jasmonic acid-mediated defense response|negative regulation by symbiont of host jasmonic acid-mediated defense response|stimulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway|positive regulation by organism of defense-related host SA-mediated signal transduction pathway|modulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway|up-regulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway Any process in which a symbiont modulates the frequency, rate or extent of the jasmonic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0003087 positive regulation of the force of heart contraction by neuronal epinephrine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003087 increased force of heart contraction by neuronal adrenaline|positive regulation of heart contraction by adrenaline|increased force of heart contraction by epinephrine released from the nerve endings|positive regulation of heart contraction by neuronal epinephrine|increased force of heart contraction by neuronal epinephrine The process in which the release of epinephrine from nerve endings modulates the force of heart muscle contraction. GO:0003086 regulation of systemic arterial blood pressure by local renal renin-angiotensin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003086 The process in which angiotensinogen metabolites in the kidney modulate the force with which blood passes through the renal circulatory system. The process begins when renin cleaves angiotensinogen. GO:0003089 positive regulation of the force of heart contraction by circulating epinephrine-norepinephrine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003089 increased force of heart contraction by circulating adrenaline-noradrenaline|positive regulation of heart contraction by circulating adrenaline-noradrenaline|positive regulation of heart contraction by circulating epinephrine-norepinephrine|increased force of heart contraction by epinephrine-norepinephrine in the blood stream|increased force of heart contraction by circulating epinephrine-norepinephrine Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine in the bloodstream. GO:0003088 positive regulation of the force of heart contraction by circulating epinephrine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003088 positive regulation of heart contraction by circulating epinephrine|increased force of heart contraction by circulating adrenaline|increased force of heart contraction by epinephrine in the bloodstream|positive regulation of heart contraction by circulating adrenaline The process in which the secretion of epinephrine into the bloodstream modulates the force of heart muscle contraction. CL:1000768 kidney connecting tubule epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000768 GO:0003083 negative regulation of renal output by angiotensin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003083 angiotensin-mediated negative regulation of renal output|angiotensin mediated negative regulation of renal output The process in which angiotensin directly decreases the rate of natriuresis and diuresis in the kidney. GO:0003082 obsolete positive regulation of renal output by angiotensin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003082 angiotensin-mediated positive regulation of renal output|positive regulation of renal output by angiotensin|angiotensin mediated positive regulation of renal output OBSOLETE. Any process in which angiotensin directly increases the rate of natriuresis and diuresis in the kidney. GO:0003085 negative regulation of systemic arterial blood pressure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003085 The process that reduces the force with which blood travels through the systemic arterial circulatory system. GO:0003084 positive regulation of systemic arterial blood pressure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003084 The process that increases the force with which blood travels through the systemic arterial circulatory system. GO:0003090 positive regulation of the force of heart contraction by neuronal epinephrine-norepinephrine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003090 increased force of heart contraction by neuronal adrenaline-noradrenaline|positive regulation of heart contraction by adrenaline-noradrenaline|positive regulation of heart contraction by epinephrine-norepinephrine|increased force of heart contraction by epinephrine-norepinephrine released from the nerve endings|increased force of heart contraction by neuronal epinephrine-norepinephrine Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine released from the nerve endings. GO:0052090 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052090 GO:0003092 renal water retention biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003092 negative regulation of renal water excretion The process in which renal water excretion is decreased. RO:0000057 has participant biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0000057 RO:0000057 a relation between a process and a continuant, in which the continuant is somehow involved in the process GO:0003091 renal water homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003091 water homeostasis by the renal system Renal process involved in the maintenance of an internal steady state of water in the body. GO:0052094 formation of haustorium for nutrient acquisition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052094 formation by symbiont of haustorium for nutrient acquisition from host|formation by organism of haustorium for nutrient acquisition from host|formation by organism of haustoria for nutrient acquisition from host The assembly of a haustorium, a projection from a symbiotic cell or tissue that penetrates the host's tissues for the purpose of obtaining nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052093 formation of specialized structure for nutrient acquisition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052093 formation by symbiont of specialized structure for nutrient acquisition from host|formation of specialized structure for nutrient acquisition from host|formation by organism of specialized structure for nutrient acquisition from host The assembly of a symbiotic cellular or anatomical structure for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052092 positive regulation by symbiont of nutrient release from host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052092 promotion of nutrient release from host|up regulation by symbiont of nutrient release from host|upregulation by symbiont of nutrient release from host|stimulation by symbiont of nutrient release from host|up-regulation by symbiont of nutrient release from host|activation by symbiont of nutrient release from host Any process in which an organism activates, maintains or increases the frequency, rate or extent of the release of nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052091 modulation by symbiont of nutrient release from host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052091 Any process in which an organism modulates the frequency, rate or extent of the release of nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052098 formation by host of specialized structure for nutrient acquisition from symbiont biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052098 The assembly by an organism of a cellular component or anatomical structure for the purpose of obtaining nutrients from a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052097 obsolete interspecies quorum sensing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052097 OBSOLETE. The process in which a community of single-celled organisms of different species monitors population density by detecting the concentration of small diffusible signal molecules. GO:0052096 formation of syncytium involving giant cell for nutrient acquisition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052096 formation by symbiont of syncytium involving giant cell for nutrient acquisition from host|https://github.com/geneontology/go-ontology/issues/20305|formation by organism of syncytium involving giant cell for nutrient acquisition from host The assembly of a syncytium, a multi-nucleate and physiologically active aggregation of fused root cells induced by a symbiotic nematode in a plant host. The syncytium exclusively provides the nematode with nourishment during its sedentary life, for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052095 formation of specialized structure for nutrient acquisition from other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052095 formation of specialized structure for nutrient acquisition from other organism during symbiotic interaction The assembly by an organism of a cellular component or anatomical structure for the purpose of obtaining nutrients from a second organism, where the two organisms are in a symbiotic interaction. CHEBI:4047 L-cysteinylglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_4047 GO:0052099 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052099 GO:0003058 hormonal regulation of the force of heart contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003058 hormonal regulation of the force of heart muscle contraction|hormonal cardiac inotropy The process in which the hormones modulates the force of heart muscle contraction. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action. GO:0003057 regulation of the force of heart contraction by chemical signal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003057 regulation of the force of heart muscle contraction by chemical signal|chemical cardiac inotropy The regulation of the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine. GO:0003059 positive regulation of the force of heart contraction by epinephrine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003059 positive regulation of heart contraction by adrenaline|epinephrine cardiac inotropy|adrenaline cardiac inotropy|increased force of heart contraction by epinephrine|adrenaline regulation of the strength of heart muscle contraction|positive regulation of heart contraction by epinephrine The process in which the secretion of epinephrine into the bloodstream or released from nerve endings modulates the force of heart muscle contraction. GO:0003054 circadian regulation of systemic arterial blood pressure by the suprachiasmatic nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003054 SCN regulation of blood pressure|master pacemaker clock regulation of blood pressure The process in which the suprachiasmatic nucleus modulates blood pressure at different values with a regularity of approximately 24 hours. RO:0000052 inheres in biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0000052 RO:0000052 a relation between a specifically dependent continuant (the dependent) and an independent continuant (the bearer), in which the dependent specifically depends on the bearer for its existence GO:0003053 circadian regulation of heart rate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003053 circadian regulation of heart contraction rate Any process in which an organism modulates its heart rate at different values with a regularity of approximately 24 hours. GO:0003056 regulation of vascular associated smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003056 regulation of vascular smooth muscle contraction Any process that increases the frequency, rate or extent of vascular smooth muscle contraction. GO:0003055 circadian regulation of heart rate by the suprachiasmatic nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003055 circadian regulation of heart contraction rate by the suprachiasmatic nucleus|SCN regulation of heart rate|master pacemaker clock regulation of heart rate The process in which the suprachiasmatic nucleus modulates heart rate at different values with a regularity of approximately 24 hours. RO:0000056 participates in biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0000056 RO:0000056 a relation between a continuant and a process, in which the continuant is somehow involved in the process GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003050 blood pressure regulation by ANP|blood pressure regulation by atrial natriuretic peptide The regulation of blood pressure mediated by the signaling molecule atrial natriuretic peptide. GO:0003052 circadian regulation of systemic arterial blood pressure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003052 Any process in which an organism modulates its blood pressure at different values with a regularity of approximately 24 hours. RO:0000053 bearer of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0000053 RO:0000053 a relation between an independent continuant (the bearer) and a specifically dependent continuant (the dependent), in which the dependent specifically depends on the bearer for its existence GO:0003051 angiotensin-mediated drinking behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003051 angiotensin mediated drinking behavior The drinking behavior that is mediated by the action of angiotensin in the brain. Angiotensin stimulates the brain centers that control thirst. OBO:GOCHE_33280 substance with molecular messenger role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_33280 GO:0003069 acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003069 vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure The process in which acetylcholine signaling causes vasodilation, resulting in a change in blood pressure. OBO:GOCHE_33284 substance with nutrient role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_33284 GO:0003068 regulation of systemic arterial blood pressure by acetylcholine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003068 blood pressure regulation by acetylcholine The regulation of blood pressure mediated by acetylcholine signaling. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter. OBO:GOCHE_33281 substance with antimicrobial agent role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_33281 GO:0003065 positive regulation of heart rate by epinephrine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003065 adrenaline regulation of the rate of heart muscle contraction|adrenaline cardiac chronotropy|positive regulation of heart contraction rate by epinephrine|epinephrine cardiac chronotropy|positive regulation of heart rate by adrenaline The process in which the secretion of epinephrine into the bloodstream or released from nerve endings increases the rate of heart muscle contraction. GO:0003064 regulation of heart rate by hormone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003064 regulation of the rate of heart contraction by hormone|hormonal cardiac chronotropy The process in which the hormones modulates the rate of heart muscle contraction. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action. GO:0003067 circadian regulation of systemic arterial blood pressure by hormone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003067 The process in which hormones modulate the force with which blood passes through the circulatory system contributing to different values of blood pressure oscillating with a regularity of approximately 24 hours. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action. GO:0003066 positive regulation of heart rate by norepinephrine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003066 positive regulation of heart contraction rate by norepinephrine|noradrenaline cardiac chronotropy|noradrenaline regulation of the rate of heart muscle contraction|norepinephrine cardiac chronotropy|positive regulation of heart rate by adrenaline The process in which the secretion of norepinephrine into the bloodstream or released from nerve endings increases the rate of heart muscle contraction. GO:0003061 positive regulation of the force of heart contraction by norepinephrine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003061 norepinephrine cardiac inotropy|noradrenaline cardiac inotropy|increased force of heart contraction by adrenaline|positive regulation of heart contraction by adrenaline|noradrenaline regulation of the strength of heart muscle contraction|increased force of heart contraction by norepinephrine|positive regulation of heart contraction by norepinephrine The process in which the secretion of norepinephrine into the bloodstream or released from nerve endings modulates the force of heart musclecontraction. CHEBI:146022 alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->4)]-N-acetyl-beta-D-glucosaminide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_146022 GO:0003060 negative regulation of the force of heart contraction by acetylcholine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003060 decreased force of heart contraction by acetylcholine The process in which acetylcholine released from vagus nerve endings binds to muscarinic receptors and decreases the force of heart muscle contraction. CHEBI:146021 N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-D-glucosaminide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_146021 GO:0003063 negative regulation of heart rate by acetylcholine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003063 negative regulation of heart contraction rate by acetylcholine The process in which acetylcholine released from vagus nerve endings binds to muscarinic receptors on the pacemaker cells and decreases the rate of heart muscle contraction. GO:0003062 regulation of heart rate by chemical signal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003062 chemical cardiac chronotropy|chemical signal regulation of heart rate|chemical signal regulation of heart contraction rate The regulation of the rate of heart contraction mediated by chemical signaling, hormonal, autocrine or paracrine. CHEBI:4027 cyclophosphamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_4027 GO:0003070 regulation of systemic arterial blood pressure by neurotransmitter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003070 The regulation of blood pressure mediated by a neurotransmitter. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. OBO:GOCHE_23888 substance with drug role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_23888 CHEBI:29656 neomethymycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29656 CHEBI:4083 D-4-hydroxy-2-oxoglutaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_4083 CHEBI:29658 oleandolide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29658 GO:0042640 anagen biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0042640 hair growth The growth phase of the hair cycle. Lasts, for example, about 3 to 6 years for human scalp hair. UBERON:0007491 chitin-based acellular structure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007491 Acellular anatomical structure whose predominant constituent is chitin. UBERON:0007490 keratin-based acellular structure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007490 keratin-based structure Acellular anatomical structure whose predominant constituent is keratin. GO:0042642 actomyosin, myosin complex part biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042642 The myosin part of any complex of actin, myosin, and accessory proteins. GO:0042641 actomyosin biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042641 actomyosin structure|actomyosin complex Any complex of actin, myosin, and accessory proteins. CHEBI:29651 neoabietadiene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29651 CHEBI:29650 narbonolide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29650 GO:0042648 chloroplast chromosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042648 A circular DNA molecule containing chloroplast encoded genes. UBERON:0007499 epithelial sac biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007499 An epithelial tube that is open at one end only. GO:0042647 proplastid nucleoid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042647 The region of a proplastid to which the DNA is confined. GO:0042649 prothylakoid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042649 Underdeveloped thylakoids found in etioplasts, lacking competent photosynthetic membranes. Rapidly develop into mature thylakoids in the presence of light. GO:0042644 chloroplast nucleoid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042644 The region of a chloroplast to which the DNA is confined. GO:0042643 obsolete actomyosin, actin portion biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042643 OBSOLETE. The actin part of any complex of actin, myosin, and accessory proteins. GO:0042646 plastid nucleoid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042646 The region of a plastid to which the DNA is confined. GO:0042645 mitochondrial nucleoid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042645 The region of a mitochondrion to which the DNA is confined. CHEBI:4075 (R)-(1-aminoethyl)phosphonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_4075 CHEBI:4077 (4R,5S,6R)-2,4,5,6-tetrahydroxycyclohex-2-en-1-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_4077 CHEBI:30659 D-thyroxine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30659 CHEBI:30657 D-homoserine lactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30657 CHEBI:30655 L-homoserine lactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30655 CHEBI:4093 D-allopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_4093 CHEBI:30654 D-homoserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30654 CHEBI:29669 pyochelin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29669 GO:0042651 thylakoid membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042651 The pigmented membrane of any thylakoid. GO:0042650 prothylakoid membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042650 The membrane of prothylakoids, underdeveloped thylakoids found in etioplasts, lacking competent photosynthetic membranes. GO:0042653 mitochondrial respiratory chain complex I, membrane segment biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042653 NADH-Q oxidoreductase complex, membrane segment The mitochondrial membrane segment of respiratory chain complex I. Respiratory chain complex I is an enzyme of the respiratory chain, consisting of at least 34 polypeptide chains. The electrons of NADH enter the chain at this complex. The complete complex is L-shaped, with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix. GO:0042652 mitochondrial respiratory chain complex I, peripheral segment biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042652 NADH-Q oxidoreductase complex, peripheral segment|NADH dehydrogenase (ubiquinone) complex, peripheral segment The peripheral segment of respiratory chain complex I located in the mitochondrion. Respiratory chain complex I is an enzyme of the respiratory chain, consisting of at least 34 polypeptide chains. The electrons of NADH enter the chain at this complex. The complete complex is L-shaped, with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix. CHEBI:29665 pikromycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29665 GO:0042659 regulation of cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042659 Any process that mediates the adoption of a specific fate by a cell. GO:0042658 MHC class II protein binding, via antigen binding groove biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042658 major histocompatibility complex class II protein binding, via antigen binding groove Interacting selectively and non-covalently with the antigen binding groove of major histocompatibility complex class II molecules. GO:0042655 activation of JNKKK activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042655 activation of JUN kinase kinase kinase activity|positive regulation of JUNKKK activity The initiation of the activity of the inactive enzyme JUN kinase kinase kinase (JNKKK) activity. GO:0042654 ecdysis-triggering hormone receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042654 ecdysis-triggering hormone binding|ETH receptor Combining with ecdysis-triggering hormone to initiate a change in cell activity. GO:0042657 MHC class II protein binding, via lateral surface biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042657 major histocompatibility complex class II protein binding, via lateral surface Interacting selectively and non-covalently with the lateral surface of major histocompatibility complex class II molecules. GO:0042656 JUN kinase kinase kinase kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042656 JUNKKKK activity Catalysis of the phosphorylation and activation of JUN kinase kinase kinases (JNKKKs). CHEBI:30653 homoserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30653 CHEBI:30624 D-mannuronate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30624 CHEBI:30623 oxalate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30623 GO:0042662 negative regulation of mesodermal cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042662 down-regulation of mesodermal cell fate specification|suppression of mesodermal cell fate|downregulation of mesodermal cell fate specification|down regulation of mesodermal cell fate specification|inhibition of mesodermal cell fate specification Any process that stops, prevents, or reduces the frequency, rate or extent of mesoderm cell fate specification. GO:0042661 regulation of mesodermal cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042661 Any process that modulates the frequency, rate or extent of mesoderm cell fate specification. CHEBI:29630 methymycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29630 OBO:GOCHE_33232 substance with application role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_33232 GO:0042664 negative regulation of endodermal cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042664 down-regulation of endodermal cell fate specification|suppression of endodermal cell fate|downregulation of endodermal cell fate specification|negative regulation of endoderm cell fate specification|down regulation of endodermal cell fate specification|inhibition of endodermal cell fate specification|suppression of endoderm cell fate Any process that restricts, stops or prevents a cell from specifying into an endoderm cell. GO:0042663 regulation of endodermal cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042663 regulation of endoderm cell fate specification Any process that mediates the specification of a cell into an endoderm cell. GO:0042660 positive regulation of cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042660 up-regulation of cell fate specification|upregulation of cell fate specification|up regulation of cell fate specification|activation of cell fate specification|stimulation of cell fate specification Any process that activates or enables a cell to adopt a specific fate. GO:0042669 regulation of inner ear auditory receptor cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042669 regulation of inner ear auditory receptor cell fate specification|regulation of auditory hair cell fate specification Any process that mediates the specification of a cell into an auditory hair cell. OBO:GOCHE_33229 substance with vitamin role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_33229 UBERON:0007475 matrix-based tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007475 A tissue whose predominant feature is extracellular matrix which may or may not be highly hydrated or calcified. GO:0042666 negative regulation of ectodermal cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042666 down-regulation of ectodermal cell fate specification|suppression of ectodermal cell fate|downregulation of ectodermal cell fate specification|negative regulation of ectoderm cell fate specification|down regulation of ectodermal cell fate specification|inhibition of ectodermal cell fate specification|suppression of ectoderm cell fate Any process that restricts, stops or prevents a cell from specifying into an ectoderm cell. UBERON:0007473 lumen of epithelial sac biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007473 cavity of vesicle The space within an epithelial sphere. GO:0042665 regulation of ectodermal cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042665 regulation of ectoderm cell fate specification Any process that mediates the specification of a cell into an ectoderm cell. GO:0042668 auditory receptor cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042668 auditory hair cell fate determination The process in which a cell becomes capable of differentiating autonomously into an auditory hair cell regardless of its environment; upon determination, the cell fate cannot be reversed. GO:0042667 auditory receptor cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042667 auditory hair cell fate specification The process in which a cell becomes capable of differentiating autonomously into an auditory hair cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. CHEBI:30620 (S)-2,3-dihydrodipicolinate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30620 CHEBI:15022 electron donor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15022 CHEBI:4056 cytochrome biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_4056 CHEBI:29649 narbomycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29649 CHEBI:30633 L-pipecolate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30633 CHEBI:30632 loganic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30632 GO:0042673 regulation of retinal cone cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042673 Any process that mediates the specification of a cell into a retinal cone cell. GO:0042672 retinal cone cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042672 The process in which a cell becomes capable of differentiating autonomously into a retinal cone cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. GO:0042675 compound eye cone cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042675 The process in which a relatively unspecialized cell acquires the specialized features of a compound eye cone cell, a cone-shaped cell, that focuses light in a compound eye. CL:1000746 glomerular cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000746 GO:0042674 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042674 GO:0042671 retinal cone cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042671 The process in which a cell becomes capable of differentiating autonomously into a retinal cone cell regardless of its environment; upon determination, the cell fate cannot be reversed. CL:1000742 glomerular mesangial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000742 intraglomerular mesangial cell Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. GO:0042670 retinal cone cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042670 The process in which a relatively unspecialized cell acquires the specialized features of a retinal cone cell. GO:0042677 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042677 GO:0042676 compound eye cone cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042676 The process in which the cone cells of the compound eye, the lens-secreting cells in the ommatidia, adopt pathways of differentiation that lead to the establishment of their distinct cell type. GO:0042679 compound eye cone cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042679 The process in which a cell becomes capable of differentiating autonomously into a compound eye cone cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. GO:0042678 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042678 GO:0052007 obsolete biosynthesis by symbiont of substance in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052007 biosynthesis by organism of substance in host OBSOLETE. The chemical reactions and pathways performed by an organism in its host resulting in the formation of substances. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:30605 disulfanyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30605 GO:0052006 catabolism by symbiont of substance in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052006 catabolism by organism of substance in host The chemical reactions and pathways performed by an organism in its host resulting in the breakdown of substances. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:29616 abieta-8(14),12-diene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29616 GO:0052005 suppression by symbiont of host ethylene-mediated defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052005 negative regulation by symbiont of defense-related host ethylene-mediated signal transduction pathway|inhibition by symbiont of host ethylene-mediated defense response|suppression by organism of host ethylene-mediated defense response|down regulation by symbiont of host ethylene-mediated defense response|negative regulation by organism of ethylene-mediated defense response of other organism involved in symbiotic interaction|downregulation by symbiont of host ethylene-mediated defense response|negative regulation by organism of defense-related ethylene-mediated signal transduction pathway in other organism involved in symbiotic interaction|negative regulation by symbiont of host ethylene-mediated defense response|down-regulation by symbiont of host ethylene-mediated defense response Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the ethylene-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:30604 disulfanide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30604 GO:0052004 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052004 CHEBI:29613 3-O-(alpha-L-oleandrosyl)oleandolide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29613 GO:0052009 disruption by symbiont of host cell wall biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052009 disassembly by symbiont of host cell wall A process carried out by a symbiont that breaks down the cell wall of its host. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052008 disruption by symbiont of host cellular component biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052008 catabolism of host structural constituent by organism|disassembly by symbiont of host cellular component|degradation of host cellular component by organism|disassembly by organism of host cellular component|catabolism of host cellular component by organism The chemical reactions and pathways performed by an organism resulting in the breakdown of cellular components of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:29614 3-O-(alpha-L-olivosyl)oleandolide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29614 GO:0042684 cardioblast cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042684 The process in which a cell becomes committed to becoming a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. GO:0042683 negative regulation of compound eye cone cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042683 down-regulation of cone cell fate specification|suppression of cone cell fate|downregulation of cone cell fate specification|down regulation of cone cell fate specification|inhibition of cone cell fate specification Any process that restricts, stops or prevents a cell from specifying into a compound eye cone cell. GO:0042686 regulation of cardioblast cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042686 Any process that mediates the specification of a cell into a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. GO:0042685 cardioblast cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042685 The process in which a cell becomes capable of differentiating autonomously into a cardioblast cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. GO:0042680 compound eye cone cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042680 The process in which a cell becomes capable of differentiating autonomously into a compound eye cone cell regardless of its environment; upon determination, the cell fate cannot be reversed. GO:0042682 regulation of compound eye cone cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042682 Any process that mediates the specification of a cell into a compound eye cone cell. GO:0042681 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042681 GO:0042688 crystal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042688 The process in which a hemocyte precursor cell acquires the characteristics of a crystal cell, a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph. GO:0042687 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042687 GO:0042689 regulation of crystal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042689 Any process that modulates the frequency, rate or extent of crystal cell differentiation. GO:0052003 suppression by symbiont of defense-related host salicylic acid-mediated signal transduction pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052003 negative modulation by organism of defense-related host salicylic acid-mediated signal transduction pathway|down regulation by symbiont of host salicylic acid-mediated defense response|downregulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|negative regulation by organism of salicylic acid-mediated defense response of other organism involved in symbiotic interaction|negative regulation by organism of defense-related host SA-mediated signal transduction pathway|downregulation by symbiont of host salicylic acid-mediated defense response|down regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|negative regulation of host SA-mediated defense response|inhibition by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|down-regulation by symbiont of host salicylic acid-mediated defense response|negative regulation by symbiont of host salicylic acid-mediated defense response|negative regulation by organism of defense-related salicylic acid-mediated signal transduction pathway of other organism involved in symbiotic interaction|negative modulation by organism of defense-related host SA-mediated signal transduction pathway|inhibition by symbiont of host salicylic acid-mediated defense response|suppression by organism of host salicylic acid-mediated defense response|down-regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|negative regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|suppression of host SA mediated defense response Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of host salicylic acid-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052002 metabolism by symbiont of substance in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052002 The chemical reactions and pathways performed by an organism in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052001 type IV pili-dependent localized adherence to host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052001 Attachment of bacterial clusters to the surface of the host in a type IV pili dependent manner. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052000 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052000 CHEBI:30617 MgATP(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30617 GO:0052018 modulation by symbiont of RNA levels in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052018 modulation by symbiont of host RNA levels The alteration by an organism of the levels of RNA in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052017 catabolism by symbiont of host xylan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052017 catabolism by organism of host xylan The chemical reactions and pathways performed by an organism resulting in the breakdown of xylan within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:30616 ATP(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30616 GO:0052016 catabolism by symbiont of host glucan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052016 catabolism by organism of host glucan The chemical reactions and pathways performed by an organism resulting in the breakdown of glucan molecules within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052015 catabolism by symbiont of host carbohydrate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052015 catabolism by organism of host carbohydrate The chemical reactions and pathways performed by an organism resulting in the breakdown of carbohydrate molecules within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:30613 glucarate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30613 CHEBI:30612 D-glucarate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30612 GO:0052019 modulation by symbiont of host hormone or growth regulator levels biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052019 modulation by organism of hormone or growth regulator levels in other organism involved in symbiotic interaction The alteration by an organism of the levels of hormones or growth regulators in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0042695 thelarche biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042695 Wikipedia:Thelarche The beginning of development of the breasts in the female. GO:0042694 muscle cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042694 The process in which a cell becomes capable of differentiating autonomously into a muscle cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. GO:0042697 menopause biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0042697 Wikipedia:Menopause Cessation of menstruation, occurring in (e.g.) the human female usually around the age of 50. GO:0042696 menarche biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0042696 Wikipedia:Menarche The beginning of the menstrual cycle; the first menstrual cycle in an individual. GO:0042691 positive regulation of crystal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042691 up regulation of crystal cell differentiation|upregulation of crystal cell differentiation|stimulation of crystal cell differentiation|up-regulation of crystal cell differentiation|activation of crystal cell differentiation Any process that activates or increases the frequency, rate or extent of crystal cell differentiation. GO:0042690 negative regulation of crystal cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042690 down-regulation of crystal cell differentiation|downregulation of crystal cell differentiation|down regulation of crystal cell differentiation|inhibition of crystal cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of crystal cell differentiation. CHEBI:30619 2,4-divinyl protochlorophyllide a biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30619 GO:0042693 muscle cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042693 The process in which the cellular identity of muscle cells is acquired and determined. GO:0042692 muscle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042692 myogenesis The process in which a relatively unspecialized cell acquires specialized features of a muscle cell. GO:0042699 follicle-stimulating hormone signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042699 follicle stimulating hormone signaling pathway|follicle stimulating hormone signalling pathway|follicle-stimulating hormone signalling pathway The series of molecular signals mediated by follicle-stimulating hormone. GO:0042698 ovulation cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042698 The type of sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years. GO:0052010 catabolism by symbiont of host cell wall cellulose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052010 catabolism by organism of host cell wall cellulose The chemical reactions and pathways performed by an organism resulting in the breakdown of cellulose in the host cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052014 catabolism by symbiont of host protein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052014 catabolism by organism of host protein The chemical reactions and pathways performed by an organism resulting in the breakdown of protein macromolecules within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052013 catabolism by symbiont of host macromolecule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052013 catabolism by organism of host macromolecule The chemical reactions and pathways performed by an organism resulting in the breakdown of macromolecules within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052012 catabolism by symbiont of host cell wall chitin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052012 catabolism by organism of host cell wall chitin The chemical reactions and pathways performed by an organism resulting in the breakdown of chitin in the host cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052011 catabolism by symbiont of host cell wall pectin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052011 catabolism by organism of host cell wall pectin The chemical reactions and pathways performed by an organism resulting in the breakdown of pectin in the host cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052029 suppression by symbiont of host signal transduction pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052029 negative regulation by symbiont of host signal transduction pathway|down-regulation by symbiont of host signal transduction pathway|negative modulation by organism of host signal transduction pathway|downregulation by symbiont of host signal transduction pathway|negative regulation by organism of signal transduction in other organism involved in symbiotic interaction|down regulation by symbiont of host signal transduction pathway|inhibition by symbiont of host signal transduction pathway Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the host signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052028 induction by symbiont of host signal transduction pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052028 positive regulation by symbiont of host signal transduction pathway|up regulation by symbiont of host signal transduction pathway|positive regulation by organism of signal transduction in other organism involved in symbiotic interaction|positive regulation of signal transduction in other organism|upregulation by symbiont of host signal transduction pathway|stimulation by symbiont of host signal transduction pathway|up-regulation by symbiont of host signal transduction pathway|activation by symbiont of host signal transduction pathway Any process in which an organism activates, maintains or increases the frequency, rate or extent of the host signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052027 modulation by symbiont of host signal transduction pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052027 modulation of host signal transduction by symbiont|modulation by symbiont of host signal transduction|regulation by symbiont of host signal transduction pathway|modulation of signal transduction in other organism involved in symbiotic interaction Any process in which an organism modulates the frequency, rate or extent of the host signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052026 modulation by symbiont of host transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052026 Any process in which an organism modulates the frequency, rate or extent of its host's transcription. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052021 modulation by symbiont of ethylene levels in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052021 modulation by organism of ethylene levels in other organism involved in symbiotic interaction The alteration by an organism of the levels of ethylene in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052020 modification by symbiont of host cell wall biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052020 metabolism of host cell wall by organism The process in which an organism effects a change in the structure or function of the host cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052025 modification by symbiont of host cell membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052025 modification by symbiont of host cell membrane The process in which an organism effects a change in the structure or function of a host cellular membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052024 positive regulation by symbiont of hormone or growth regulator levels in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052024 positive modulation of hormone or growth regulator levels in host|up regulation by symbiont of hormone or growth regulator levels in host|positive regulation by organism of hormone or growth regulator levels in other organism involved in symbiotic interaction|upregulation by symbiont of hormone or growth regulator levels in host|stimulation by symbiont of hormone or growth regulator levels in host|up-regulation by symbiont of hormone or growth regulator levels in host|activation by symbiont of hormone or growth regulator levels in host The increase by an organism of the levels of hormones or growth regulators in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052023 modulation by symbiont of salicylic acid levels in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052023 modulation by organism of salicylic acid levels in other organism involved in symbiotic interaction The alteration by an organism of the levels of salicylic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052022 modulation by symbiont of jasmonic acid levels in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052022 modulation by organism of jasmonic acid levels in other organism involved in symbiotic interaction The alteration by an organism of the levels of jasmonic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052039 modification by symbiont of host cytoskeleton biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052039 rounding by symbiont of host cells The process in which an organism effects a change in the structure or function of the host cytoskeleton. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:29605 gibberellin A9 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29605 GO:0052038 modulation by symbiont of host intracellular transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052038 modulation of host intracellular trafficking Any process in which an organism modulates the frequency, rate or extent of the directed movement of substances within the cell or cells of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052037 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052037 CL:1000706 ureter urothelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000706 GO:0052032 modulation by symbiont of host inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052032 modulation by organism of inflammatory response of other organism involved in symbiotic interaction Any process in which a symbiont modulates the frequency, rate or extent of the inflammatory response of the host organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052031 modulation by symbiont of host defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052031 mitigation by symbiont of host defense response|modulation by organism of defense response of other organism involved in symbiotic interaction Any process in which an organism modulates the frequency, rate or extent of the defense response of its host, the response mounted by the host in response to the presence of the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052030 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052030 GO:0052036 suppression by symbiont of host inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052036 downregulation by symbiont of host inflammatory response|down regulation by symbiont of host inflammatory response|inhibition by symbiont of host inflammatory response|negative regulation by organism of inflammatory response of other organism involved in symbiotic interaction|down-regulation by symbiont of host inflammatory response|negative regulation by symbiont of host inflammatory response Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the inflammatory response of the host organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052035 positive regulation by symbiont of host inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052035 up regulation by symbiont of host inflammatory response|positive regulation by organism of inflammatory response of other organism involved in symbiotic interaction|upregulation by symbiont of host inflammatory response|stimulation by symbiont of host inflammatory response|up-regulation by symbiont of host inflammatory response|activation by symbiont of host inflammatory response Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of the inflammatory response of the host organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052034 suppression by symbiont of microbe-associated molecular pattern-induced host innate immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052034 downregulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity|down regulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity|inhibition by symbiont of pathogen-associated molecular pattern-induced host innate immunity|suppression of PAMP-induced host innate immunity|suppression of general elicitor induced host innate immunity|suppression of pathogen-associated molecular pattern-induced host innate immunity|suppression of MAMP-induced host innate immunity|negative regulation by symbiont of microbe-associated molecular pattern-induced host innate immune response|negative regulation by symbiont of microbe-associated molecular pattern-induced host innate immunity|negative regulation by organism of pathogen-associated molecular pattern-induced innate immune response of other organism involved in symbiotic interaction|suppression of PAMP induced host innate immunity|down-regulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity|suppression of MAMP induced host innate immunity|suppression of general elicitor-induced host innate immunity Any process that involves recognition of a microbe-associated molecular pattern, and by which a symbiont stops, prevents, or reduces the frequency, rate or extent of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052033 obsolete pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052033 pathogen-associated molecular pattern dependent activation by organism of host innate immunity|PAMP dependent activation of host innate immunity|MAMP dependent activation of host innate immunity|pattern-triggered immunity|general elicitor-dependent activation of host innate immunity|general elicitor-dependent induction of host innate immunity|pathogen-associated molecular pattern dependent induction by symbiont of host innate immunity|MAMP dependent induction of host innate immunity|PAMP dependent induction of host innate immunity|PTI OBSOLETE. Any process that involves recognition of a pathogen-associated molecular pattern, and by which an organism activates, maintains or increases the frequency, rate or extent of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:78548 adenylate cyclase agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78548 UBERON:0007530 migrating mesenchyme population biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007530 Mesenchymal cells that are migrating. CHEBI:78542 beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78542 CHEBI:78541 1-hexadecyl-2-amino-2-deoxy-sn-glycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78541 CHEBI:78547 protein kinase A agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78547 CHEBI:78559 (2S,3S)-3-hydroxy-2-methylbutanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78559 UBERON:0007521 smooth muscle sphincter biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007521 A ring of smooth muscle cells whose contraction closes the opening of the ring. CHEBI:136731 5-hydroxymethyldeoxycytidine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136731 CHEBI:136730 (S)-all-trans-4-hydroxyretinoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136730 CHEBI:136735 (R)-tetrahydropapaverine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136735 CHEBI:136734 (R)-laudanosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136734 UBERON:0007529 loose mesenchyme tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007529 Mesenchyme whose cells are embedded in obvious amounts of extracellular matrix. CHEBI:78554 2-methyl-3-hydroxybutyrate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78554 CHEBI:78552 ribonucleoside 2'-monophosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78552 CHEBI:78551 3'-(O-phosphonato-L-seryl)adenylyl(2-) group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78551 UBERON:0007524 dense mesenchyme tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007524 Mesenchyme with little extracellular matrix. CHEBI:78556 3'-(L-pyrrolysyl)adenylyl zwitterionic group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78556 UBERON:0007522 striated muscle sphincter biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007522 A ring of striated muscle cells whose contraction closes the opening of the ring. CHEBI:136708 N-acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-6-O-phosphonato-alpha-D-mannosyl-L-serine(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136708 CHEBI:136707 N-acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl-L-serine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136707 CHEBI:29593 gibberellin A34 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29593 CHEBI:136709 N-acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl-L-threonine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136709 CHEBI:136700 3-oxocholoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136700 CHEBI:136704 N-propanoyl-L-methioninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136704 PR:000006933 epidermal growth factor receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000006933 receptor tyrosine-protein kinase erbB-1|proto-oncogene c-ErbB-1|EGFR|ERBB1 An EGF receptor type tyrosine-protein kinase that is a translation product of the human EGFR gene or a 1:1 ortholog thereof. CHEBI:136703 3-oxocholan-24-oyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136703 CHEBI:136702 ximelagatran (hydroxylamine form) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136702 CHEBI:136701 3-oxodeoxycholoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136701 CHEBI:78565 beta-D-Gal-(1->3)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)- beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78565 CHEBI:30585 silicide(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30585 CHEBI:30584 silicon(4+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30584 CHEBI:78569 alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-beta-D-GalNAc-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78569 CHEBI:78568 alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78568 CHEBI:78566 1-(1Z)-alkenyl-2-acetyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78566 CHEBI:136717 C-terminal-gamma-(5-phospho-L-glutamyl )-L-glutamyl(4-) group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136717 CHEBI:136716 N-(fatty acyl)-L-alpha-amino acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136716 CHEBI:136711 N-oleoyl-L-isoleucine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136711 CHEBI:136710 N-acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-6-O-phosphonato-alpha-D-mannosyl-L-threonine(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136710 CHEBI:78572 alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78572 CHEBI:136714 C-terminal-gamma-(L-glutamyl)-L-glutamyl(3-) group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136714 CHEBI:78571 alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78571 CHEBI:136713 N-oleoyl-L-glutamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136713 CHEBI:136712 pivaloyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136712 CHEBI:78574 pyrimidinecarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78574 CHEBI:78573 3'-(L-selenocysteinyl)adenylyl(1-) group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78573 UBERON:0007503 epithelial vesicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007503 A closed epithelium with a lumen. UBERON:0007501 arborizing epithelial duct system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007501 arborising epithelial duct system A collection of connected epithelial tubes with a single portal. UBERON:0007500 epithelial tube open at both ends biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007500 An epithelial tube open at both ends that allows fluid flow. CHEBI:29579 epothilone D biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29579 CHEBI:30566 gamma-aminobutyrate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30566 CHEBI:29572 demethyllactenocin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29572 CHEBI:29571 dehydroabietic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29571 GO:0042604 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042604 GO:0042603 capsule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042603 Wikipedia:Capsule_(microbiology) A protective structure surrounding some fungi and bacteria, attached externally to the cell wall and composed primarily of polysaccharides. Capsules are highly organized structures that adhere strongly to cells and cannot be easily removed. Capsules play important roles in pathogenicity, preventing phagocytosis by other cells, adherance, and resistance to dessication. GO:0042606 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042606 GO:0042605 peptide antigen binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0042605 exogenous peptide antigen binding|endogenous peptide antigen binding Interacting selectively and non-covalently with an antigen peptide. GO:0042600 egg chorion biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0042600 A protective, noncellular membrane that surrounds the eggs of various animals including insects and fish. GO:0042602 riboflavin reductase (NADPH) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042602 KEGG_REACTION:R05707|EC:1.5.1.41|EC:1.5.1.30|MetaCyc:NADPH-DEHYDROGENASE-FLAVIN-RXN|RHEA:19377 NADPH-specific FMN reductase activity|NADPH2:riboflavin oxidoreductase activity|NADPH:riboflavin oxidoreductase activity|flavin reductase activity|NADPH-dependent FMN reductase activity|NADPH-FMN reductase activity|NADPH dehydrogenase (riboflavin) activity|NADPH-riboflavin reductase activity|NADPH-riboflavin oxidoreductase activity|FMN reductase (NADPH) activity|riboflavin mononucleotide (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|NADPH2 dehydrogenase (riboflavin)|reduced-riboflavin:NADP+ oxidoreductase activity|riboflavin mononucleotide reductase activity|riboflavine mononucleotide reductase activity Catalysis of the reaction: reduced riboflavin + NADP+ = riboflavin + NADPH + 2 H+. GO:0042601 endospore-forming forespore biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042601 Portion of the cell formed during the process of bacterial sporulation that will ultimately become the core of the endospore. An endospore is a type of dormant cell that is resistant to adverse conditions. CHEBI:30563 silicon dioxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30563 GO:0042608 T cell receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042608 T lymphocyte receptor binding|T-lymphocyte receptor binding|TCR binding|T-cell receptor binding Interacting selectively and non-covalently with a T cell receptor, the antigen-recognizing receptor on the surface of T cells. GO:0042607 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042607 CHEBI:78589 2-O,3-dimethylflaviolin-7-olate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78589 GO:0042609 CD4 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042609 Interacting selectively and non-covalently with a CD4, a receptor found on the surface of T cells, monocytes and macrophages. CHEBI:78588 6-linalyl-2-O,3-dimethylflaviolin-7-olate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78588 CHEBI:78590 7-O-geranyl-2-O,3-dimethylflaviolin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78590 GO:0042615 CD154 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042615 CD40L binding|CD40 receptor activity Interacting selectively and non-covalently with CD154, a receptor found on the surface of some activated lymphocytes. GO:0042614 CD70 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042614 CD27 receptor activity|CD27L binding Interacting selectively and non-covalently with a CD70, a receptor found on the surface of most activated B cells and some activated T cells. GO:0042617 paclitaxel biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042617 paclitaxel anabolism|paclitaxel synthesis|paclitaxel formation|taxol biosynthetic process|taxol biosynthesis|paclitaxel biosynthesis The chemical reactions and pathways resulting in the formation of paclitaxel, an alkaloid compound used as an anticancer treatment. GO:0042616 paclitaxel metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042616 taxol metabolic process|taxol metabolism|paclitaxel metabolism The chemical reactions and pathways involving paclitaxel, an alkaloid compound used as an anticancer treatment. CHEBI:78594 5alpha-pregan-20beta-ol-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78594 GO:0042611 MHC protein complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0042611 A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen. GO:0042610 CD8 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042610 Interacting selectively and non-covalently with a CD8, a receptor found on the surface of thymocytes and cytotoxic and suppressor T-lymphocytes. GO:0042613 MHC class II protein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042613 A transmembrane protein complex composed of an MHC class II alpha and MHC class II beta chain, and with or without a bound peptide or polysaccharide antigen. GO:0042612 MHC class I protein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042612 A transmembrane protein complex composed of a MHC class I alpha chain and an invariant beta2-microglobin chain, and with or without a bound peptide antigen. Class I here refers to classical class I molecules. CHEBI:78598 N-acetylamino-acid residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78598 CHEBI:78597 N-terminal alpha-amino-acid(1+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78597 CHEBI:78596 21-dehydrocortisone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78596 CHEBI:78595 21-dehydrocortisol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78595 GO:0042619 poly-hydroxybutyrate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042619 poly-hydroxybutyrate biosynthesis|PHB biosynthesis|PHB biosynthetic process|poly-hydroxybutyrate anabolism|poly-hydroxybutyrate synthesis|poly-hydroxybutyrate formation The chemical reactions and pathways resulting in the formation of poly-hydroxybutyrate (PHB), a polymer of beta-hydroxybutyrate and a common storage material of prokaryotic cells. GO:0042618 poly-hydroxybutyrate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042618 poly-hydroxybutyrate metabolism|PHB metabolism|PHB metabolic process The chemical reactions and pathways involving poly-hydroxybutyrate (PHB), a polymer of beta-hydroxybutyrate and a common storage material of prokaryotic cells. UBERON:0007567 regenerating anatomical structure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007567 regenerative tissue|regenerating tissue|regenerating tissues An anatomical structure that is undergoing regeneration. CHEBI:78599 (gamma-L-glutamyl) N-terminal alpha-amino-acid zwitterionic residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78599 PR:000016301 tyrosine 3-monooxygenase biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000016301 tyrosine 3-hydroxylase|TYH|TH A protein that is a translation product of the human TH gene or a 1:1 ortholog thereof. GO:0042620 poly(3-hydroxyalkanoate) metabolic process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0042620 PHA metabolic process|PHA metabolism|poly(3-hydroxyalkanoate) metabolism The chemical reactions and pathways involving poly(3-hydroxyalkanoates), polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria. CHEBI:29556 chloroeremomycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29556 GO:0042626 ATPase-coupled transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042626 EC:7.2.2.-|Reactome:R-HSA-2161506|Reactome:R-HSA-2161538|Reactome:R-HSA-1467457|Reactome:R-HSA-9033505|Reactome:R-HSA-9033499 P-P-bond-hydrolysis-driven transmembrane transporter activity|ATP-dependent transmembrane transporter activity|P-P-bond-hydrolysis-driven transporter|ATPase activity, coupled to movement of substances|ATP-coupled transmembrane transporter activity|ATPase activity, coupled to transmembrane movement of substances|hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances Primary active transporter of a solute across a membrane, via the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance across a membrane. The transport protein may be transiently phosphorylated (P-type transporters), or not (ABC-type transporters and other families of transporters). Primary active transport occurs up the solute's concentration gradient and is driven by a primary energy source. GO:0042625 ATPase-coupled ion transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042625 ATP-dependent ion transmembrane transporter activity|ATPase activity, coupled to transmembrane movement of ions|ATPase coupled ion transmembrane transporter activity Enables the transfer of an ion from one side of a membrane to the other, driven by the reaction: ATP + H2O = ADP + phosphate. GO:0042628 mating plug formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042628 copulatory plug biosynthesis|copulatory plug deposition|mating plug deposition|copulatory plug formation The deposition of a plug of sperm or other gelatinous material into the opening of the vulva by a male at the termination of copulation. Probably acts to prevent subsequent matings by other males. GO:0042627 chylomicron biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042627 Wikipedia:Chylomicron A large lipoprotein particle (diameter 75-1200 nm) composed of a central core of triglycerides and cholesterol surrounded by a protein-phospholipid coating. The proteins include one molecule of apolipoprotein B-48 and may include a variety of apolipoproteins, including APOAs, APOCs and APOE. Chylomicrons are found in blood or lymph and carry lipids from the intestines into other body tissues. GO:0042622 photoreceptor outer segment membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042622 The membrane surrounding the outer segment of a vertebrate photoreceptor. GO:0042621 poly(3-hydroxyalkanoate) biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042621 poly(3-hydroxyalkanoate) anabolism|poly(3-hydroxyalkanoate) synthesis|poly(3-hydroxyalkanoate) formation|PHA biosynthesis|poly(3-hydroxyalkanoate) biosynthesis|PHA biosynthetic process The chemical reactions and pathways resulting in the formation of poly(3-hydroxyalkanoates), polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria. GO:0042624 obsolete ATPase activity, uncoupled biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042624 OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction is not directly coupled to any other reaction. GO:0042623 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042623 GO:0042629 mast cell granule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042629 Coarse, bluish-black staining cytoplasmic granules, bounded by a plasma membrane and found in mast cells and basophils. Contents include histamine, heparin, chondroitin sulfates, chymase and tryptase. GO:0042631 cellular response to water deprivation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042631 cellular response to drought Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of water. GO:0042630 behavioral response to water deprivation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042630 behavioural response to water deprivation|behavioral response to drought|behavioral response to thirst Any process that results in a change in the behavior of an organism as a result of deprivation of water. PR:000006990 eukaryotic translation initiation factor 4E biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000006990 mRNA cap-binding protein|eIF-4E|EIF4E|eIF4E|EIF4EL1|eIF-4F 25 kDa subunit|EIF4F A protein that is a translation product of the human EIF4E gene or a 1:1 ortholog thereof. GO:0042637 catagen biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0042637 hair regression The regression phase of the hair cycle during which cell proliferation ceases, the hair follicle shortens, and an anchored club hair is produced. GO:0042636 negative regulation of hair cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042636 downregulation of hair cycle|down regulation of hair cycle|inhibition of hair cycle|down-regulation of hair cycle Any process that stops, prevents, or reduces the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair. GO:0042639 telogen biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0042639 hair resting phase The resting phase of hair cycle. GO:0042638 exogen biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0042638 hair shedding The shedding phase of the hair cycle. GO:0042633 hair cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042633 The cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body. GO:0042632 cholesterol homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042632 positive regulation of cholesterol homeostasis|regulation of cholesterol homeostasis Any process involved in the maintenance of an internal steady state of cholesterol within an organism or cell. GO:0042635 positive regulation of hair cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042635 up regulation of hair cycle|upregulation of hair cycle|stimulation of hair cycle|up-regulation of hair cycle|activation of hair cycle Any process that activates or increases the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair. GO:0042634 regulation of hair cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042634 Any process that modulates the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair. GO:0003039 detection of reduced oxygen by carotid body chemoreceptor signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003039 detection of reduced oxygen by carotid body chemoreceptor signalling The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in a carotid body. GO:0003036 detection of pH by aortic body chemoreceptor signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003036 detection of pH by aortic body chemoreceptor signalling The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors in an aortic body. GO:0003035 detection of increased carbon dioxide by carotid body chemoreceptor signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003035 detection of increased carbon dioxide by carotid body chemoreceptor signalling The process in which information about the levels of carbon dioxide are received and are converted to a molecular signal by chemoreceptors in a carotid body. GO:0003038 detection of reduced oxygen by aortic body chemoreceptor signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003038 detection of reduced oxygen by aortic body chemoreceptor signalling The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in an aortic body. GO:0003037 detection of pH by carotid body chemoreceptor signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003037 detection of pH by carotid body chemoreceptor signalling The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors in a carotid body. GO:0003032 detection of oxygen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003032 The series of events in which an oxygen stimulus is received by a cell and converted into a molecular signal. GO:0003031 detection of carbon dioxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003031 The series of events in which a carbon dioxide stimulus is received by a cell and converted into a molecular signal. GO:0003034 detection of increased carbon dioxide by aortic body chemoreceptor signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003034 detection of increased carbon dioxide by aortic body chemoreceptor signalling The process in which information about the levels of carbon dioxide are received and are converted to a molecular signal by chemoreceptors in an aortic body. GO:0003033 detection of hypoxic conditions in blood by aortic body chemoreceptor signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003033 detection of hypoxic conditions in blood by aortic body chemoreceptor signalling The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the aortic bodies. GO:0003030 detection of hydrogen ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003030 The series of events in which a hydrogen ion stimulus is received by a cell and converted into a molecular signal. GO:0003047 regulation of systemic arterial blood pressure by epinephrine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003047 blood pressure regulation by epinephrine|regulation of blood pressure by adrenaline The regulation of blood pressure mediated by the catecholamine signaling molecule epinephrine. GO:0003046 regulation of systemic arterial blood pressure by stress relaxation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003046 blood pressure regulation by stress relaxation The intrinsic circulatory process resulting from stress relaxation that modulates the force with which blood travels through the systemic arterial circulatory system. Stress relaxation is the adaptation of vessels to a new size as a result of changes in pressure in storage areas such as veins, the liver, the spleen, and the lungs. GO:0003049 regulation of systemic arterial blood pressure by capillary fluid shift biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003049 blood pressure regulation by capillary fluid shift The intrinsic circulatory process resulting from capillary fluid shift that modulates the force with which blood travels through the systemic arterial circulatory system. Capillary fluid shift is the movement of fluid across the capillary membrane between the blood and the interstitial fluid compartment. GO:0003048 regulation of systemic arterial blood pressure by norepinephrine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003048 blood pressure regulation by norepinephrine|regulation of blood pressure by noradrenaline The regulation of blood pressure mediated by the catecholamine signaling molecule norepinephrine. GO:0003043 vasoconstriction of artery involved in aortic body chemoreceptor response to lowering of systemic arterial blood pressure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003043 vasoconstriction of artery during aortic body chemoreceptor response to lowering of systemic arterial blood pressure A process that is triggered by aortic body-vasomotor excitation and results in a decrease in the diameter of an artery during the chemoreceptor response to decreased blood pressure. GO:0003042 vasoconstriction of artery involved in carotid body chemoreceptor response to lowering of systemic arterial blood pressure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003042 vasoconstriction of artery during carotid body chemoreceptor response to lowering of systemic arterial blood pressure A process that is triggered by carotid body-vasomotor excitation and results in a decrease in the diameter of an artery during the chemoreceptor response to decreased blood pressure. GO:0003045 regulation of systemic arterial blood pressure by physical factors biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003045 blood pressure regulation by physical factors The regulation of blood pressure mediated by detection of forces within the circulatory system. GO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003044 blood pressure regulation mediated by a chemical signal The regulation of blood pressure mediated by biochemical signaling: hormonal, autocrine or paracrine. GO:0003041 excitation of vasomotor center by carotid body chemoreceptor signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003041 excitation of vasomotor center by carotid body chemoreceptor signalling The process in which the molecular signal from a carotid body is relayed to the vasomotor center, causing it to signal an increase arterial pressure. GO:0003040 excitation of vasomotor center by aortic body chemoreceptor signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003040 excitation of vasomotor center by aortic body chemoreceptor signalling The process in which the molecular signal from an aortic body is relayed to the vasomotor center, causing it to signal an increase arterial pressure. GO:0003018 vascular process in circulatory system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003018 vasculature process A circulatory process that occurs at the level of the vasculature. GO:0003017 lymph circulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003017 The flow of lymph through the body of an animal. GO:0003019 central nervous system control of baroreceptor feedback biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003019 The neurological process in which nerve impulses arising in the aorta or the carotid sinuses travel to the medulla and reach the nucleus of tractus solaris. GO:0003014 renal system process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003014 kidney system process|excretory system process A organ system process carried out by any of the organs or tissues of the renal system. The renal system maintains fluid balance, and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels; in other species, the renal system may comprise related structures (e.g., nephrocytes and malpighian tubules in Drosophila). GO:0003013 circulatory system process biolink:BiologicalProcess go-plus goslim_generic|goslim_chembl http://purl.obolibrary.org/obo/GO_0003013 Wikipedia:Circulatory_system A organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism. GO:0003016 respiratory system process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003016 respiratory gaseous exchange A process carried out by the organs or tissues of the respiratory system. The respiratory system is an organ system responsible for respiratory gaseous exchange. GO:0003015 heart process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003015 cardiac process A circulatory system process carried out by the heart. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. GO:0003010 voluntary skeletal muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003010 A process in which force is generated within voluntary skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the voluntary skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and it is under voluntary control. Voluntary skeletal muscle is skeletal muscle that is under conscious control. GO:0003012 muscle system process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003012 muscle physiological process A organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers. GO:0003011 involuntary skeletal muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003011 A process in which force is generated within involuntary skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Involuntary skeletal muscle is skeletal muscle that is not under conscious control. GO:0003029 detection of hypoxic conditions in blood by carotid body chemoreceptor signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003029 detection of hypoxic conditions in blood by carotid body chemoreceptor signalling The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies. GO:0003028 regulation of systemic arterial blood pressure by aortic body chemoreceptor signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003028 aortic body chemoreceptor regulation of systemic arterial blood pressure|regulation of systemic arterial blood pressure by aortic body chemoreceptor signalling|aortic body chemoreceptor response to lowering of systemic arterial blood pressure The process that modulates blood pressure by the action of chemoreceptors found in the aortic bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions. GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003025 baroreceptor regulation of systemic arterial blood pressure The neural regulation of blood pressure in which baroreceptors sense the amount of stretch occurring in vessels and respond to the input via central nervous system control. GO:0003024 baroreceptor detection of decreased arterial stretch biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003024 The series of events by which a decrease in diameter of an artery is detected and converted to a molecular signal. GO:0003027 regulation of systemic arterial blood pressure by carotid body chemoreceptor signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003027 carotid body chemoreceptor response to lowering of systemic arterial blood pressure|regulation of systemic arterial blood pressure by carotid body chemoreceptor signalling|carotid body chemoreceptor regulation of systemic arterial blood pressure|vagal reflex The process that modulates blood pressure by the action of chemoreceptors found in the carotid bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions. GO:0003026 regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003026 aortic arch baroreceptor control of systemic arterial blood pressure The process that modulates blood pressure by sensing the amount of stretch occurring in the aorta and responding to the input via central nervous system control. GO:0003021 detection of increased carbon dioxide by chemoreceptor signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003021 detection of increased carbon dioxide by chemoreceptor signalling The process in which information about the levels of carbon dioxide are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies. GO:0003020 detection of reduced oxygen by chemoreceptor signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003020 detection of reduced oxygen by chemoreceptor signalling The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies. GO:0003023 baroreceptor detection of increased arterial stretch biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003023 The series of events by which an increase in diameter of an artery is detected and converted to a molecular signal. GO:0003022 detection of pH by chemoreceptor signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003022 detection of pH by chemoreceptor signalling The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors. CHEBI:136799 5-methyl-2-thiouridine 5'-phosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136799 CHEBI:136798 4-thiouridine 5'-phosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136798 CHEBI:136766 N-acetyl-L-alpha-phenylglycinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136766 CHEBI:136765 L-alpha-phenylglycine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136765 CHEBI:136763 C-terminal-gamma-(L-ornithyl)-L-glutamyl(1-) group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136763 CHEBI:136769 alpha-D-galactopyranosyl-(1->2)-alpha-D-glucopyranosyl-(1->3)-1,2-diacyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136769 CHEBI:78503 C-terminal-gamma-L-glutamyl-L-2-aminoadipate(3-) group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78503 CHEBI:136761 C-terminal-gamma-(L-glutamyl 5-semialdehyde)-L-glutamyl(2-) group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136761 CHEBI:78502 (S)-2-aminopropan-1-ol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78502 CHEBI:136760 short-chain (3S)-hydroxy fatty acyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136760 CHEBI:78501 C-terminal-gamma-L-glutamyl-L-2-aminoadipate semialdehyde(2-) group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78501 GO:0003007 heart morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003007 cardiac morphogenesis The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. GO:0003006 developmental process involved in reproduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003006 reproductive developmental process|puberty A developmental process in which a progressive change in the state of some part of an organism specifically contributes to its ability to form offspring. CHEBI:78517 3'-(L-cysteinyl)adenylyl zwitterionic group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78517 CHEBI:78516 3'-(L-aspartate)adenylyl(1-) group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78516 GO:0003009 skeletal muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003009 A process in which force is generated within skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and in most cases it is under voluntary control. GO:0003008 system process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003008 organ system process A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective. CHEBI:78515 3'-(L-asparaginyl)adenylyl(1-) group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78515 GO:0003003 follicular fluid formation in ovarian follicle antrum involved in fused antrum stage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003003 follicular fluid formation in ovarian follicle antrum during fused antrum stage The ovulation cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the fused antrum stage of oogenesis. GO:0003002 regionalization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003002 pattern formation The pattern specification process that results in the subdivision of an axis or axes in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment. GO:0003005 follicular fluid formation in ovarian follicle antrum involved in scattered antral spaces stage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003005 follicular fluid formation in ovarian follicle antrum during scattered antral spaces stage The menstrual cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the scattered antral spaces stage of oogenesis. GO:0003004 follicular fluid formation in ovarian follicle antrum involved in distinct antral spaces stage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003004 follicular fluid formation in ovarian follicle antrum during distinct antral spaces stage The menstrual cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the antral spaces stage of oogenesis. GO:0003001 obsolete generation of a signal involved in cell-cell signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003001 formation of a signal|generation of a signal involved in cell-cell signaling|generation of a signal involved in cell-cell signalling|signal generation OBSOLETE. The cellular process that creates a physical entity or change in state, i.e. a signal, that originates in one cell and is used to transfer information to another cell. This process begins with the initial formation of the signal and ends with the mature form and placement of the signal. CHEBI:78513 3'-(L-arginyl)adenylyl(1+) group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78513 CHEBI:78512 1-decanoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78512 PR:000006928 pro-epidermal growth factor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000006928 EGF A protein that is a translation product of the human EGF gene or a 1:1 ortholog thereof. CHEBI:78529 3'-(L-lysyl)adenylyl(1+) group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78529 CHEBI:78528 3'-(L-isoleucyl)adenylyl zwitterionic group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78528 CHEBI:78527 3'-(L-histidyl)adenylyl(1-) group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78527 CHEBI:78526 C-terminal-gamma-L-glutamyl-L-lysine(1-) group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78526 CHEBI:136749 5-phospho-D-xylonate (3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136749 CHEBI:136743 2-O-[6-O-octanoyl-alpha-D-glucosyl-(1->6)-alpha-D-glucosyl]-D-glycerate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136743 CHEBI:136742 2-O-[alpha-D-glucosyl-(1->6)-alpha-D-glucosyl]-D-glycerate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136742 CHEBI:136746 5-phospho-D-xylonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136746 CHEBI:78521 3'-(L-glutaminyl)adenylyl zwitterionic group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78521 CHEBI:78520 3'-(L-glutamate)adenylyl(1-) group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78520 CHEBI:78525 L-glutamo(2-) group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78525 CHEBI:78522 3'-glycyladenylyl zwitterionic group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78522 CHEBI:78537 3'-(L-valyl)adenylyl zwitterionic group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78537 CHEBI:136754 5-phospho-L-arabinonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136754 CHEBI:136753 L-arabino-1,4-lactone-5-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136753 CHEBI:136752 L-arabino-1,4-lactone-5-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136752 CHEBI:136759 (22E)-3-oxochola-4,22-dien-24-oyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136759 CHEBI:136758 long-chain 3-oxo-fatty acyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136758 CHEBI:136757 long-chain (3S)-hydroxy fatty acyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136757 CHEBI:136756 5-phospho-L-arabinonate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136756 CHEBI:78532 3'-(L-prolyl)adenylyl zwitterionic group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78532 CHEBI:78531 3'-(L-phenylalanyl)adenylyl(1-) group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78531 CHEBI:78530 3'-(L-methionyl)adenylyl zwitterionic group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78530 PR:000006909 elongation factor 2 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000006909 EEF2|EF2|EF-2 A protein that is a translation product of the human EEF2 gene or a 1:1 ortholog thereof. CHEBI:136751 D-xylono-1,4-lactone-5-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136751 CHEBI:78536 3'-(L-tyrosyl)adenylyl(1-) group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78536 CHEBI:78535 3'-(L-tryptophyl)adenylyl(1-) group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78535 CHEBI:136750 D-xylono-1,4-lactone-5-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136750 CHEBI:78534 3'-(L-threonyl)adenylyl(1-) group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78534 CHEBI:78533 3'-(L-seryl)adenylyl(1-) group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78533 GO:0052169 obsolete pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052169 pathogen-associated molecular pattern dependent modulation by symbiont of host innate immunity OBSOLETE. Any process that involves recognition of a pathogen-associated molecular pattern, and by which an organism modulates the frequency, rate or extent of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052160 modulation by symbiont of host systemic acquired resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052160 modulation by symbiont of systemic acquired resistance in host|modulation by organism of systemic acquired resistance in other organism involved in symbiotic interaction Any process in which a symbiont modulates the frequency, rate or extent of systemic acquired resistance in the host organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052164 symbiont defense to host-produced reactive oxygen species biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052164 modulation by organism of defense-related host ROI production|evasion or tolerance by symbiont of reactive oxygen species produced by other organism involved in symbiotic interaction|response to defense-related host reactive oxygen species production|evasion or tolerance of defense-related host oxidative burst|modulation by organism of defense-related host metabolic burst|evasion or tolerance by organism of host-produced reactive oxygen species|response to defense-related reactive oxygen species production by other organism involved in symbiotic interaction|evasion or tolerance of host-produced AOS|modulation by organism of defense-related host ROS production|modulation by organism of defense-related host active oxygen species production|evasion or tolerance of host-produced reactive oxygen intermediates|modulation by organism of defense-related host respiratory burst|evasion or tolerance of host-produced ROIs|modulation by symbiont of defense-related host reactive oxygen species production|evasion or tolerance of defense-related host metabolic burst|modulation by organism of defense-related host reactive oxygen intermediate production|evasion or tolerance by organism of reactive oxygen species produced by other organism involved in symbiotic interaction|modulation by organism of defense-related host reactive oxidative species production|evasion or tolerance of host-produced active oxygen species|evasion by symbiont of cellular damage caused by host oxidative burst|modulation by organism of defense-related host oxidative burst|evasion or tolerance of host-produced ROS|modulation by organism of defense-related host AOS production|evasion or tolerance by organism of reactive oxygen species produced during host defense response|evasion or tolerance by symbiont of host-produced reactive oxygen species|evasion or tolerance of defense-related host respiratory burst|modulation by organism of defense-related reactive oxygen species production in other organism involved in symbiotic interaction|evasion or tolerance of reactive oxygen species produced by host Any process in which a symbiont modulates the frequency, rate or extent of the production of reactive oxygen species as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052163 symbiont defense to host-produced nitric oxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052163 modulation by organism of defense-related host NO production|evasion or tolerance of nitric oxide produced by host in response to organism|modulation by symbiont of defense-related host nitric oxide production|evasion or tolerance by organism of nitric oxide produced by other organism involved in symbiotic interaction|evasion or tolerance by organism of host nitric oxide|evasion or tolerance by organism of host-produced nitric oxide|response to defense-related nitric oxide production by other organism involved in symbiotic interaction|evasion or tolerance of NO produced by host in response to organism|modulation by organism of defense-related nitric oxide production in other organism involved in symbiotic interaction|response to defense-related host nitric oxide production|evasion or tolerance by symbiont of host-produced nitric oxide|evasion or tolerance by organism of host NO|evasion or tolerance by organism of host-produced NO|defense response to host innate immune response nitric oxide production Any process in which a symbiont modulates the frequency, rate or extent of the production of nitric oxide as part of the innate immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052162 modulation by symbiont of defense-related host calcium ion flux biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052162 modulation by organism of defense-related host Ca2+ flux|modulation by organism of defense-related calcium ion flux in other organism involved in symbiotic interaction Any process in which an organism modulates the frequency, rate or extent of calcium ion fluxes as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052161 obsolete modulation by symbiont of defense-related host cell wall thickening biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052161 modulation by organism of host defensive cell wall thickening|modulation by organism of defense-related cell wall thickening in other organism involved in symbiotic interaction OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of host processes resulting in the thickening of its cell walls, occurring as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052168 modulation by symbiont of defense-related host calcium-dependent protein kinase pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052168 modulation by organism of defense-related calcium-dependent protein kinase pathway in other organism involved in symbiotic interaction|modulation by organism of defense-related host CDPK pathway Any process in which an organism modulates the frequency, rate or extent of the host calcium-dependent protein kinase signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052167 modulation by symbiont of host innate immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052167 modulation by symbiont of host innate immunity|modulation of host innate immune response|modulation by organism of innate immune response in other organism involved in symbiotic interaction Any process in which a symbiont modulates the frequency, rate or extent of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052166 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052166 GO:0052165 symbiont defense to host-produced phytoalexin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052165 modulation by symbiont of host phytoalexin production|host phytoalexin detoxification|response to host phytoalexin production|evasion or tolerance of phytoalexins produced by host in response to organism|response to phytoalexin production by other organism involved in symbiotic interaction|modulation by organism of phytoalexin production in other organism involved in symbiotic interaction|evasion or tolerance by symbiont of host-produced phytoalexins|phytoalexin detoxification|evasion or tolerance of phytoalexins Any process in which a symbiont modulates the frequency, rate or extent of production of phytoalexins as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052171 obsolete growth or development during symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052171 growth or development during symbiotic interaction OBSOLETE. The increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring when the organism is in a symbiotic interaction. GO:0052170 suppression by symbiont of host innate immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052170 downregulation by symbiont of host innate immunity|down regulation by symbiont of host innate immunity|inhibition by symbiont of host innate immunity|negative regulation of host innate immune response|down-regulation by symbiont of host innate immunity|negative regulation of innate immune response in other organism|negative regulation by symbiont of host innate immunity|negative regulation by symbiont of host innate immune response Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the innate immune response of the host organism, the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction. UBERON_CORE:posteriorly_connected_to posteriorly connected to biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/uberon/core#posteriorly_connected_to posteriorly_connected_to x posteriorly_connected_to y iff the posterior part of x is connected to y. i.e. x connected_to y and x anterior_to y. GO:0052175 metabolism by symbiont of host carbohydrate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052175 The chemical reactions and pathways performed by an organism involving carbohydrates within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052174 metabolism by symbiont of host macromolecule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052174 The chemical reactions and pathways performed by an organism involving macromolecules within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052173 response to defenses of other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052173 response to defenses of other organism during symbiotic interaction|response to defenses of other organism involved in symbiotic interaction Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the defenses of another organism. GO:0052172 metabolism by symbiont of host cell wall cellulose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052172 The chemical reactions and pathways performed by an organism involving cellulose in the cell wall of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052179 metabolism by symbiont of host cell wall pectin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052179 The chemical reactions and pathways performed by an organism involving pectin in the cell wall of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052178 metabolism by symbiont of host cell wall chitin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052178 The chemical reactions and pathways performed by an organism involving chitin in the cell wall of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052177 metabolism by symbiont of host xylan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052177 The chemical reactions and pathways performed by an organism involving xylan within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052176 metabolism by symbiont of host glucan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052176 The chemical reactions and pathways performed by an organism involving glucans within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052182 obsolete modification by host of symbiont morphology or physiology via secreted substance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052182 OBSOLETE. The process in which an organism effects a change in the structure or function of a symbiont organism, mediated by a substance secreted by one of the organisms. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052181 obsolete modulation by host of symbiont defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052181 OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the resistance gene-dependent defense response of the symbiont. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052180 negative regulation of peptidase activity in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052180 downregulation of protease activity in other organism during symbiotic interaction|down regulation of protease activity in other organism during symbiotic interaction|inhibition of protease activity in other organism during symbiotic interaction|negative regulation of protease activity in other organism during symbiotic interaction|down-regulation of protease activity in other organism during symbiotic interaction Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of protease activity, the catalysis of the hydrolysis of peptide bonds in a protein, in a second organism, where the two organisms are in a symbiotic interaction. GO:0052186 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052186 GO:0052185 modification of structure of other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052185 modification of structure of other organism during symbiotic interaction The process in which an organism effects a change in an anatomical part or cellular component of a second organism, where the two organisms are in a symbiotic interaction. GO:0052184 obsolete modulation by organism of symbiont hormone or growth regulator levels biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052184 modulation by organism of symbiont hormone or growth regulator levels OBSOLETE. The alteration by an organism of the levels of hormones or growth regulators in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052183 modification by host of symbiont structure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052183 The process in which an organism effects a change in an anatomical part or cellular component of the host organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052189 obsolete modulation by symbiont of defense-related host cell wall callose deposition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052189 modulation by symbiont of defense-related host callose deposition|modulation by organism of defense-related cell wall callose deposition in other organism involved in symbiotic interaction|modulation by organism of defense-related callose deposition of other organism involved in symbiotic interaction OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of the deposition of callose by the host in its cell walls, occurring as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052188 modification of cellular component in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052188 modification of cellular component in other organism during symbiotic interaction The process in which an organism effects a change in the structure or function of a cellular component in a second organism, where the two organisms are in a symbiotic interaction. GO:0052187 modification by host of symbiont cellular component biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052187 The process in which an organism effects a change in the structure or function of a symbiont cellular component. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052193 obsolete movement in symbiont environment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052193 OBSOLETE. The directed movement of an organism or motile cell on, within or near its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052192 obsolete movement in environment of other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052192 locomotion in environment of other organism during symbiotic interaction|movement in environment of other organism during symbiotic interaction OBSOLETE. The directed movement of an organism or motile cell on, within or near a second organism, where the two organisms are in a symbiotic interaction. GO:0052191 obsolete positive regulation by symbiont of host phagocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052191 up regulation by symbiont of host phagocytosis|activation by symbiont of host phagocytosis|stimulation by symbiont of host phagocytosis|up-regulation by symbiont of host phagocytosis|upregulation by symbiont of host phagocytosis OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052190 obsolete modulation by symbiont of host phagocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052190 OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052197 obsolete positive regulation by host of symbiont defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052197 activation by host of symbiont defense response|stimulation by host of symbiont defense response|up-regulation by host of symbiont defense response|upregulation by host of symbiont defense response|up regulation by host of symbiont defense response OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052196 obsolete negative regulation by host of symbiont defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052196 down-regulation by host of symbiont defense response|inhibition by host of symbiont defense response|down regulation by host of symbiont defense response|downregulation by host of symbiont defense response OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052195 obsolete movement on or near other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052195 movement on or near other organism during symbiotic interaction OBSOLETE. The directed movement of an organism or motile cell on or near a second organism, where the two organisms are in a symbiotic interaction. GO:0052194 obsolete movement on or near symbiont biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052194 OBSOLETE. The directed movement of an organism or motile cell on or near its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052199 down-regulation of enzyme activity in other organism during symbiotic interaction|inhibition of enzyme activity in other organism during symbiotic interaction|downregulation of enzyme activity in other organism during symbiotic interaction|inhibition of enzyme activity in other organism|down regulation of enzyme activity in other organism during symbiotic interaction|negative regulation of enzyme activity in other organism during symbiotic interaction Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of enzyme activity in a second organism, where the two organisms are in a symbiotic interaction. GO:0052198 modulation of peptidase activity in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052198 modulation of protease activity in other organism involved in symbiotic interaction|modulation of protease activity in other organism during symbiotic interaction The process in which an organism effects a change in peptidase activity, the catalysis of the hydrolysis of peptide bonds in a protein, in a second organism, where the two organisms are in a symbiotic interaction. CHEBI:146179 galactotriose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_146179 GO:0003197 endocardial cushion development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003197 The progression of a cardiac cushion over time, from its initial formation to the mature structure. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. GO:0003196 ventriculo bulbo valve formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003196 The developmental process pertaining to the initial formation of the ventriculo bulbo valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003199 endocardial cushion to mesenchymal transition involved in valve formation A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of a cardiac valve. GO:0003198 epithelial to mesenchymal transition involved in endocardial cushion formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003198 A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of the endocardial cushion. GO:0003193 pulmonary valve formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003193 The developmental process pertaining to the initial formation of the pulmonary valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. CHEBI:146176 levomethorphan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_146176 GO:0003192 mitral valve formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003192 The developmental process pertaining to the initial formation of the mitral valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. GO:0003195 tricuspid valve formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003195 The developmental process pertaining to the initial formation of the tricuspid valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. CHEBI:146178 6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_146178 GO:0003194 sinoatrial valve formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003194 SA valve formation The developmental process pertaining to the initial formation of the sinoatrial valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. CHEBI:146181 mannotriose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_146181 CHEBI:146180 glucotriose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_146180 GO:0003179 heart valve morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003179 heart valve remodeling|heart valve remodelling The process in which the structure of a heart valve is generated and organized. GO:0003178 coronary sinus valve development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003178 The progression of the valve of the coronary sinus over time, from its formation to the mature structure. GO:0003175 tricuspid valve development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003175 The progression of the tricuspid valve over time, from its formation to the mature structure. GO:0003174 mitral valve development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003174 The progression of the mitral valve over time, from its formation to the mature structure. GO:0003177 pulmonary valve development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003177 The progression of the pulmonary valve over time, from its formation to the mature structure. GO:0003176 aortic valve development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003176 The progression of the aortic valve over time, from its formation to the mature structure. GO:0003171 atrioventricular valve development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003171 AV valve development The progression of the atrioventricular valve over time, from its formation to the mature structure. GO:0003170 heart valve development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003170 cardiac valve development The progression of a heart valve over time, from its formation to the mature structure. A heart valve is a structure that restricts the flow of blood to different regions of the heart and forms from an endocardial cushion. GO:0003173 ventriculo bulbo valve development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003173 The progression of the ventriculo bulbo valve over time, from its formation to the mature structure. GO:0003172 sinoatrial valve development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003172 SA valve development The progression of the sinoatrial valve over time, from its formation to the mature structure. GO:0003180 aortic valve morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003180 The process in which the structure of the aortic valve is generated and organized. GO:0003189 aortic valve formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003189 The developmental process pertaining to the initial formation of the aortic valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. GO:0003186 tricuspid valve morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003186 The process in which the structure of the tricuspid valve is generated and organized. GO:0003185 sinoatrial valve morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003185 SA valve morphogenesis The process in which the structure of the sinoatrial valve is generated and organized. GO:0003188 heart valve formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003188 The developmental process pertaining to the initial formation of a heart valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. CHEBI:146140 4alpha-hydroxymethyl-4beta-methyl-5alpha-cholest-7-en-3beta-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_146140 GO:0003187 ventriculo bulbo valve morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003187 The process in which the structure of the ventriculo bulbo valve is generated and organized. GO:0003182 coronary sinus valve morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003182 The process in which the structure of the coronary sinus valve is generated and organized. GO:0003181 atrioventricular valve morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003181 AV valve morphogenesis The process in which the structure of the atrioventricular valve is generated and organized. GO:0003184 pulmonary valve morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003184 The process in which the structure of the pulmonary valve is generated and organized. GO:0003183 mitral valve morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003183 The process in which the structure of the mitral valve is generated and organized. GO:0003191 coronary sinus valve formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003191 The developmental process pertaining to the initial formation of the coronary sinus valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. GO:0003190 atrioventricular valve formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003190 AV valve formation The developmental process pertaining to the initial formation of the atrioventricular valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. CHEBI:30528 vanadium oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30528 CHEBI:30527 flavin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30527 CHEBI:30526 1-aminocyclopropanecarboxylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30526 GO:0042761 very long-chain fatty acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042761 MetaCyc:PWY-5080 very-long-chain fatty acid biosynthesis|very-long-chain fatty acid biosynthetic process|very-long-chain fatty acid anabolism|very-long-chain fatty acid synthesis|very-long-chain fatty acid formation The chemical reactions and pathways resulting in the formation of a fatty acid which has a chain length greater than C22. GO:0042760 very long-chain fatty acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042760 very-long-chain fatty acid breakdown|very-long-chain fatty acid catabolism|very-long-chain fatty acid catabolic process|very-long-chain fatty acid degradation The chemical reactions and pathways resulting in the breakdown of a fatty acid which has a chain length greater than C22. GO:0042763 intracellular immature spore biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042763 forespore A cell or part of the cell that constitutes an early developmental stage of a spore, a small reproductive body that is highly resistant to desiccation and heat and is capable of growing into a new organism, produced especially by certain bacteria, fungi, algae, and nonflowering plants. GO:0042762 regulation of sulfur metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042762 regulation of sulfur metabolism|regulation of sulphur metabolism|regulation of sulphur metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur, the nonmetallic element sulfur or compounds that contain sulfur. GO:0042769 DNA damage response, detection of DNA damage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042769 DNA damage response, perception of DNA damage|detection of DNA damage during DNA damage response The series of events required to receive a stimulus indicating DNA damage has occurred and convert it to a molecular signal. CL:1000850 macula densa epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000850 GO:0042768 ecdysteroid 2-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042768 Catalysis of the hydroxylation of an ecdysteroid at carbon position 2. GO:0042765 GPI-anchor transamidase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042765 GPIT complex An enzyme complex which in humans and yeast consists of at least five proteins; for example, the complex contains GAA1, GPI8, PIG-S, PIG-U, and PIG-T in human, and Gaa1p, Gab1p, Gpi8p, Gpi16p, and Gpi17p in yeast. Catalyzes the posttranslational attachment of the carboxy-terminus of a precursor protein to a GPI-anchor. GO:0042764 ascospore-type prospore biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042764 An immature spore undergoing development. The spore usually consists of nucleic acid, prospore membrane(s) that encase the nucleic acid, and ultimately a cell wall that covers the membrane(s). This type of spore is observed in ascospore-forming fungi. GO:0042767 ecdysteroid 22-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042767 Catalysis of the hydroxylation of an ecdysteroid at carbon position 22. GO:0042766 nucleosome mobilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042766 nucleosome sliding The movement of nucleosomes along a DNA fragment. CL:1000849 kidney distal convoluted tubule epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000849 GO:0042772 DNA damage response, signal transduction resulting in transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042772 A cascade of processes initiated in response to the detection of DNA damage, and resulting in the induction of transcription. GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042771 DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage, and ends when the execution phase of apoptosis is triggered. GO:0042774 plasma membrane ATP synthesis coupled electron transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042774 The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP in the plasma membrane. GO:0042773 ATP synthesis coupled electron transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042773 The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP. GO:0042770 signal transduction in response to DNA damage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042770 response to DNA damage stimulus by intracellular signaling cascade|DNA damage response, signal transduction A cascade of processes induced by the detection of DNA damage within a cell. GO:0042779 tRNA 3'-trailer cleavage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042779 removal of tRNA 3'-trailer sequence|tRNA 3'-end cleavage Cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA; may involve endonucleolytic or exonucleolytic cleavage, or both. GO:0042776 mitochondrial ATP synthesis coupled proton transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042776 mitochondrial proton transport The transport of protons across a mitochondrial membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis. GO:0042775 mitochondrial ATP synthesis coupled electron transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042775 organelle ATP synthesis coupled electron transport|mitochondrial electron transport The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP, as it occurs in the mitochondrial inner membrane or chloroplast thylakoid membrane. GO:0042778 tRNA end turnover biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042778 The process in which the 3'-terminal CCA of a tRNA is removed and restored. This often happens to uncharged tRNA. GO:0042777 plasma membrane ATP synthesis coupled proton transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042777 ATP synthesis coupled proton transport The transport of protons across the plasma membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis. CHEBI:30531 pimelic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30531 GO:0052106 obsolete quorum sensing involved in interaction with host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052106 quorum sensing during interaction with host OBSOLETE. The process in which a community of single-celled organisms living in intimate contact with a host organism monitors population density by detecting the concentration of small diffusible signal molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052105 obsolete induction by symbiont of defense-related host cell wall thickening biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052105 induction by organism of defense-related cell wall thickening in other organism involved in symbiotic interaction|upregulation by symbiont of defense-related host cell wall thickening|positive regulation by organism of host defensive cell wall thickening|activation by organism of host defensive cell wall thickening|up regulation by symbiont of defense-related host cell wall thickening|activation by symbiont of defense-related host cell wall thickening|positive regulation by symbiont of defense-related host cell wall thickening|positive regulation by organism of defense-related cell wall thickening in other organism involved in symbiotic interaction|induction by organism of host defensive cell wall thickening|stimulation by symbiont of defense-related host cell wall thickening|up-regulation by symbiont of defense-related host cell wall thickening|activation by organism of defense-related host cell wall thickening OBSOLETE. The activation by an organism of host processes resulting in the thickening of its cell walls, occurring as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052104 induction by symbiont of host systemic acquired resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052104 activation by organism of SAR in host|induction by organism of systemic acquired resistance in other organism involved in symbiotic interaction|up-regulation by symbiont of systemic acquired resistance in host|stimulation by symbiont of systemic acquired resistance in host|induction by organism of SAR in host|positive regulation by symbiont of host systemic acquired resistance|positive regulation by symbiont of systemic acquired resistance in host|up regulation by symbiont of systemic acquired resistance in host|positive regulation by organism of systemic acquired resistance in other organism involved in symbiotic interaction|activation by organism of systemic acquired resistance in host|induction by symbiont of systemic acquired resistance in host|upregulation by symbiont of systemic acquired resistance in host Any process in which a symbiont activates systemic acquired resistance in the host organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052103 induction by symbiont of host induced systemic resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052103 positive regulation by symbiont of host induced systemic resistance|induction by organism of ISR in host|induction by organism of induced systemic resistance in other organism involved in symbiotic interaction|induction by symbiont of induced systemic resistance in host|up-regulation by symbiont of induced systemic resistance in host|activation by organism of induced systemic resistance in host|upregulation by symbiont of induced systemic resistance in host|positive regulation by organism of induced systemic resistance in other organism involved in symbiotic interaction|activation by symbiont of induced systemic resistance in host|stimulation by symbiont of induced systemic resistance in host|up regulation by symbiont of induced systemic resistance in host|activation by organism of ISR in host|positive regulation by symbiont of induced systemic resistance in host Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of induced systemic resistance in the host organism; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:29519 aphidicolan-16beta-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29519 CHEBI:29514 5-amino-5-deoxy-3-dehydroshikimic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29514 GO:0052109 obsolete induction by symbiont of defense-related host cell wall callose deposition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052109 positive regulation by symbiont of defense-related host callose deposition|positive regulation by organism of defense-related callose deposition in other organism involved in symbiotic interaction|up regulation by symbiont of defense-related host cell wall callose deposition|positive regulation by symbiont of defense-related host cell wall callose deposition|activation by symbiont of defense-related host cell wall callose deposition|positive regulation by organism of defense-related cell wall callose deposition in other organism involved in symbiotic interaction|stimulation by symbiont of defense-related host cell wall callose deposition|up-regulation by symbiont of defense-related host cell wall callose deposition|upregulation by symbiont of defense-related host cell wall callose deposition OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the deposition of callose by the host in its cell walls, occurring as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052108 obsolete growth or development of symbiont during interaction with host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052108 growth or development of symbiont during interaction with host|growth or development of organism during interaction with host|growth or development of organism in response to host OBSOLETE. The increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052107 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052107 GO:0042783 evasion of host immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042783 active immune evasion|passive evasion of host immune response|active evasion of host immune response|evasion or tolerance of host immune response|passive evasion of immune response of other organism involved in symbiotic interaction|mitigation of host immune response|immune evasion|active evasion of immune response of other organism involved in symbiotic interaction|passive immune evasion A process by which an organism avoids the effects of the host organism's immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction. UBERON:0007590 cuboidal oviduct epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007590 A cuboidal epithelium that is part of a oviduct. CHEBI:29510 abietol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29510 GO:0042782 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042782 GO:0042785 evasion of host immune response via regulation of host cytokine network biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042785 active evasion of host immune response via regulation of host cytokine network|active immune evasion via modulation of host cytokine network|active immune evasion via regulation of host cytokine network|active evasion of immune response of other organism via regulation of cytokine network of other organism involved in symbiotic interaction Any mechanism of active immune avoidance which works by regulating host cytokine networks, e.g. by secreting proteins that mimic cytokine receptors that act to sequester host cytokines and inhibit action. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0042784 evasion of host immune response via regulation of host complement system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042784 active evasion of host immune response via regulation of host complement system|active evasion of immune response of other organism via regulation of complement system of other organism involved in symbiotic interaction|active immune evasion via regulation of host complement system|active immune evasion via modulation of host complement system Any mechanism of active immune avoidance which works by regulating the host complement system, e.g. by possessing complement receptors which mediate attachment to, then infection of, host macrophages, which are eventually destroyed. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0042781 3'-tRNA processing endoribonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042781 MetaCyc:3.1.26.11-RXN tRNA 3 endonuclease activity|3 tRNase activity|tRNAse Z|RNase Z activity|3' tRNA processing endoribonuclease activity|ribonuclease Z activity|tRNA 3' endonuclease activity|3' tRNase activity Catalysis of the endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule. GO:0042780 tRNA 3'-end processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042780 tRNA 3' processing The process in which the 3' end of a pre-tRNA molecule is converted to that of a mature tRNA. GO:0042787 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042787 GO:0042786 evasion of host immune response via regulation of host antigen processing and presentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042786 active immune evasion via regulation of antigen processing and presentation|active evasion of host immune response via regulation of host antigen processing and presentation pathway|active immune evasion via modulation of antigen processing/presentation|active evasion of host immune response via regulation of host antigen processing and presentation|active immune evasion via modulation of antigen processing and presentation|active evasion of immune response of other organism via regulation of antigen processing and presentation in other organism involved in symbiotic interaction Any mechanism of active immune avoidance which works by regulating the host's antigen processing or presentation pathways, e.g. by blocking any stage in MHC class II presentation. The host is defined as the larger of the organisms involved in a symbiotic interaction. UBERON:0007592 ciliated columnar epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007592 Simple columnar epithelium in which the luminal side of the cells bears cilia. Examples: epithelium of trachea, epithelium of uterine tube.[FMA] GO:0042789 mRNA transcription by RNA polymerase II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042789 mRNA transcription from RNA polymerase II promoter|mRNA transcription from Pol II promoter The cellular synthesis of messenger RNA (mRNA) from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter. GO:0042788 polysomal ribosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042788 active ribosome A ribosome bound to mRNA that forms part of a polysome. GO:0052102 positive regulation by symbiont of defense-related host calcium-dependent protein kinase pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052102 up-regulation by symbiont of defense-related host calcium-dependent protein kinase pathway|upregulation by symbiont of defense-related host calcium-dependent protein kinase pathway|positive regulation of defense-related host CDPK pathway by organism|up regulation by symbiont of defense-related host calcium-dependent protein kinase pathway|activation by symbiont of defense-related host calcium-dependent protein kinase pathway|stimulation by symbiont of defense-related host calcium-dependent protein kinase pathway|positive regulation by organism of defense-related calcium-dependent protein kinase pathway in other organism involved in symbiotic interaction Any process in which an organism activates, maintains or increases the frequency, rate or extent of the host calcium-dependent protein kinase pathway during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052101 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052101 GO:0052100 obsolete intraspecies quorum sensing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052100 OBSOLETE. The process in which single-celled organisms of the same species monitor population density by detecting the concentration of small, diffusible signal molecules. GO:0052117 obsolete aerotaxis in host environment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052117 aerotaxis in response to host environment OBSOLETE. The movement of a motile cell or organism in response to environmental oxygen on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052116 obsolete chemotaxis in host environment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052116 chemotaxis in response to host environment OBSOLETE. The directed movement of a motile cell or organism in response to a specific chemical concentration gradient on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052115 obsolete energy taxis in host environment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052115 energy taxis in response to host environment OBSOLETE. The directed movement of a motile cell or organism in the environment of its host organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052114 obsolete adaptation to host pH environment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052114 adaptation to host pH environment|pH tolerance to host environment OBSOLETE. The responsive adjustment of an organism to the pH conditions in or around its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:30514 caesium atom biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30514 CHEBI:30513 antimony atom biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30513 GO:0052119 obsolete negative energy taxis in host environment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052119 negative energy taxis in response to host environment OBSOLETE. The directed movement of a motile cell or organism on, within or near its host organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:30512 silver atom biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30512 GO:0052118 obsolete positive energy taxis in host environment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052118 positive energy taxis in response to host environment OBSOLETE. The directed movement of a motile cell or organism on, within or near its host organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0042794 plastid rRNA transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042794 rRNA transcription from plastid promoter The synthesis of ribosomal RNA (rRNA) from a plastid DNA template, usually by a specific plastid RNA polymerase. GO:0042793 plastid transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042793 transcription from plastid promoter The synthesis of RNA from a plastid DNA template, usually by a specific plastid RNA polymerase. GO:0042796 snRNA transcription by RNA polymerase III biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042796 snRNA transcription from RNA polymerase III promoter|snRNA transcription from Pol III promoter The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase III (Pol III), originating at a Pol III promoter. GO:0042795 snRNA transcription by RNA polymerase II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042795 snRNA transcription from RNA polymerase II promoter|snRNA transcription from Pol II promoter The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase II (Pol II), originating at a Pol II promoter. GO:0042790 nucleolar large rRNA transcription by RNA polymerase I biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042790 transcription of nucleolar large rRNA by RNA polymerase I|transcription of nuclear rRNA large Pol I transcript|transcription of nuclear large rRNA transcript from RNA polymerase I promoter The synthesis of the large ribosomal RNA (rRNA) transcript which encodes several rRNAs, e.g. in mammals 28S, 18S and 5.8S, from a nuclear DNA template transcribed by RNA polymerase I. GO:0042792 mitochondrial rRNA transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042792 rRNA transcription from mitochondrial promoter The synthesis of ribosomal RNA (rRNA) from a mitochondrial DNA template. GO:0042791 5S class rRNA transcription by RNA polymerase III biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042791 5S rRNA transcription|5S class rRNA transcription from RNA polymerase III type 1 promoter The synthesis of 5S ribosomal RNA (rRNA), or an equivalent rRNA, from a DNA template by RNA polymerase III (Pol III), originating at a type 1 RNA polymerase III promoter. GO:0042798 obsolete protein neddylation during NEDD8 class-dependent protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042798 protein neddylation during NEDD8 class-dependent protein degradation|protein neddylation during NEDD8 class-dependent protein breakdown|protein neddylation during NEDD8 class-dependent protein catabolic process|protein neddylation during RUB1-dependent protein catabolism|protein neddylation during RUB1-dependent protein catabolic process|protein neddylation during NEDD8 class-dependent protein catabolism OBSOLETE. Covalent attachment of the ubiquitin-like protein NEDD8 (or equivalent protein) to another protein, as a part of NEDD8-dependant protein catabolism. GO:0042797 tRNA transcription by RNA polymerase III biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042797 tRNA transcription from Pol III promoter|tRNA transcription from RNA polymerase III promoter The synthesis of transfer RNA (tRNA) from a DNA template by RNA polymerase III (Pol III), originating at a Pol III promoter. GO:0042799 histone methyltransferase activity (H4-K20 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042799 Reactome:R-HSA-2301205|Reactome:R-HSA-5682965 histone methylase activity (H4-K20 specific)|histone lysine N-methyltransferase activity (H4-K20 specific)|histone H4 lysine 20-specific methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + histone H4 L-lysine (position 20) = S-adenosyl-L-homocysteine + histone H4 N6-methyl-L-lysine (position 20). This reaction is the addition of a methyl group onto lysine at position 20 of the histone H4 protein. GO:0052113 obsolete adaptation to host osmotic environment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052113 adaptation to host osmotic environment|osmotic tolerance to host environment OBSOLETE. The responsive adjustment of an organism to the osmotic conditions in or around its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052112 occlusion by symbiont of host xylem biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052112 The process in which an organism reduces the flow of fluid within the host xylem, the tissue in plants that carries water and nutrients up from the roots to the shoot and leaves. The host is defined as the larger of the organisms involved in a symbiotic interaction. UBERON:0007589 ciliated columnar oviduct epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007589 epithelium of uterine tube|uterine tube epithelium A ciliated columnar epithelium that is part of a oviduct. GO:0052111 modification by symbiont of host structure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052111 The process in which an organism effects a change in an anatomical part or cellular component of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052110 occlusion by symbiont of host vascular system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052110 The process in which an organism reduces the flow of fluid within its host's vascular system, the vessels and tissue that carry or circulate fluids, such as blood, lymph or sap, through the body of an animal or plant. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052128 positive energy taxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052128 The directed movement of a motile cell or organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. GO:0052127 obsolete movement on or near host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052127 OBSOLETE. The directed movement of an organism or motile cell on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052126 movement in host environment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052126 movement in response to host The directed movement of an organism or motile cell on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052125 obsolete energy taxis on or near host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052125 OBSOLETE. The directed movement of a motile cell or organism on or near its host organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052129 negative energy taxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052129 The directed movement of a motile cell or organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. GO:0052120 obsolete positive aerotaxis in host environment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052120 positive aerotaxis in response to host environment OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052124 obsolete energy taxis within host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052124 OBSOLETE. The directed movement of a motile cell or organism within its host organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052123 obsolete negative chemotaxis in host environment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052123 negative chemotaxis in response to host environment OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of a specific chemical on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052122 obsolete negative aerotaxis in host environment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052122 negative aerotaxis in response to host environment OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052121 obsolete positive chemotaxis in host environment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052121 positive chemotaxis in response to host environment OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of a chemical on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052139 obsolete negative chemotaxis in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052139 negative chemotaxis within host OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of a specific chemical within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:29507 3-amino-5-hydroxybenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29507 GO:0052138 obsolete aerotaxis on or near host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052138 OBSOLETE. The movement of a motile cell or organism in response to environmental oxygen on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:29509 abietal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29509 GO:0052137 obsolete aerotaxis in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052137 aerotaxis within host OBSOLETE. The movement of a motile cell or organism in response to environmental oxygen within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052136 obsolete negative chemotaxis on or near host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052136 OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of a specific chemical on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:29505 A47934 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29505 GO:0052131 positive aerotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052131 The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen. GO:0052130 negative aerotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052130 The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen. GO:0052135 obsolete negative aerotaxis in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052135 negative aerotaxis within host OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052134 obsolete negative aerotaxis on or near host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052134 OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052133 obsolete positive aerotaxis in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052133 positive aerotaxis within host OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052132 obsolete positive aerotaxis on or near host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052132 OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052149 modulation by symbiont of host peptidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052149 modulation by symbiont of host protease activity The process in which an organism effects a change in host peptidase activity, the catalysis of the hydrolysis of peptide bonds in a protein. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052148 modulation by symbiont of host catalytic activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052148 modulation of catalytic activity of host by symbiont|modulation by symbiont of host enzyme activity|regulation of host catalytic activity by symbiont|regulation by symbiont of host catalytic activity|regulation of catalytic activity of host by symbiont The process in which an organism effects a change in host enzyme activity. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052147 obsolete positive energy taxis in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052147 positive energy taxis within host OBSOLETE. The directed movement of a motile cell or organism within its host organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction. CL:1000839 kidney proximal straight tubule epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000839 CL:1000838 kidney proximal convoluted tubule epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000838 GO:0052142 obsolete chemotaxis within host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052142 OBSOLETE. The directed movement of a motile cell or organism in response to a specific chemical concentration gradient within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052141 obsolete positive chemotaxis on or near host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052141 OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of a specific chemical on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052140 obsolete positive chemotaxis in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052140 positive chemotaxis within host OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of a specific chemical within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052146 obsolete positive energy taxis on or near host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052146 OBSOLETE. The directed movement of a motile cell or organism on or near its host organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052145 obsolete negative energy taxis on or near host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052145 OBSOLETE. The directed movement of a motile cell or organism on or near its host organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052144 obsolete negative energy taxis in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052144 negative energy taxis within host OBSOLETE. The directed movement of a motile cell or organism within its host organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052143 obsolete chemotaxis on or near host involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052143 chemotaxis on or near host during symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism in response to a specific chemical concentration gradient on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052159 modulation by symbiont of host induced systemic resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052159 modulation by organism of induced systemic resistance in other organism involved in symbiotic interaction|modulation by symbiont of induced systemic resistance in host Any process in which a symbiont modulates the frequency, rate or extent of induced systemic resistance in the host organism; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052158 modulation by symbiont of host resistance gene-dependent defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052158 modulation by organism of resistance gene-dependent defense response of other organism involved in symbiotic interaction|modulation by organism of pathogen-race/host plant cultivar-specific resistance in symbiont|modulation by organism of defense response in host by specific elicitors|modulation by organism of host gene-for-gene resistance Any process in which a symbiont modulates the frequency, rate or extent of the resistance gene-dependent defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052153 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052153 GO:0052152 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052152 GO:0052151 positive regulation by symbiont of host apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052151 induction by symbiont of host apoptosis|activation by organism of host apoptosis|activation by organism of host apoptotic programmed cell death|stimulation by symbiont of host apoptosis|activation by symbiont of host apoptosis|up-regulation by symbiont of host apoptosis|positive regulation by organism of host apoptotic programmed cell death|up regulation by organism of host apoptotic programmed cell death|positive regulation by symbiont of host apoptosis|up regulation by symbiont of host apoptosis|upregulation by organism of host apoptotic programmed cell death|induction by organism of host apoptotic programmed cell death|up-regulation by organism of host apoptotic programmed cell death|upregulation by symbiont of host apoptosis Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052150 modulation by symbiont of host apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052150 modulation by organism of host apoptotic programmed cell death|modulation by symbiont of host apoptosis Any process in which an organism modulates the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052157 obsolete modulation by symbiont of microbe-associated molecular pattern-induced host innate immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052157 modulation by organism of microbe-associated molecular pattern-induced innate immune response in other organism involved in symbiotic interaction|modulation by symbiont of microbe-associated molecular pattern-induced host innate immunity|modulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity OBSOLETE. Any process that involves recognition of a microbe-associated molecular pattern, and by which a symbiont modulates the frequency, rate or extent of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052156 modulation by symbiont of host T-cell mediated immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052156 modulation by organism of T-cell mediated immune response of other organism involved in symbiotic interaction Any process in which an organism modulates the frequency, rate or extent of the T-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052155 modulation by symbiont of host cell-mediated immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052155 modulation by organism of cell-mediated immune response of other organism involved in symbiotic interaction|modulation by organism of host cell-based immune response Any process in which an organism modulates the frequency, rate or extent of any form of cell-based immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052154 modulation by symbiont of host B-cell mediated immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052154 modulation by organism of B-cell mediated immune response of other organism involved in symbiotic interaction|regulation by organism of host B-cell mediated immune response Any process in which a symbiont modulates the frequency, rate or extent of the B-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:78429 1-alkyl-2-acyl-3-(3-O-sulfo-beta-D-galactosyl)-sn-glycerol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78429 CHEBI:78428 1-alkyl-2-acyl-3-(beta-D-galactosyl)-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78428 OBO:GOCHE_23924 substance with enzyme inhibitor role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_23924 CHEBI:136849 3-oxo-Delta(4)-steroid group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136849 CHEBI:136848 beta-bitter acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136848 UBERON:0007652 esophageal sphincter biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007652 A sphincter that is part of an esophagus. CHEBI:136842 tenuazonic acid(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136842 UBERON:0007651 anatomical junction biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007651 junction|anatomical junction An anatomical structure that connects two structures CHEBI:136841 nickel-sirohydrochlorin(8-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136841 CHEBI:136840 pheophytin a(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136840 CHEBI:30488 sulfonium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30488 CHEBI:78421 1-oleoyl-2-acyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78421 CHEBI:30485 selenonium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30485 CHEBI:78426 1-(3-O-sulfo-beta-D-galactosyl-(1->4)-beta-D-glucosyl)-N-acylsphingosine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78426 CHEBI:78424 18-hydroxyoleate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78424 CHEBI:78423 (R)-11-hydroxylaurate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78423 CHEBI:78438 alpha-N-acetylneuraminosyl-(2->8)-alpha-N-acetylneuraminosyl-(2->8)-alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphingosine(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78438 NCBITaxon:7898 Actinopterygii organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_7898 Actinopterygi|bony fishes|fishes|ray-finned fishes|fish|Osteichthyes CHEBI:136859 pro-agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136859 CHEBI:136853 3-(acyloxy)acyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136853 CHEBI:30490 tetrahydridooxygen(2+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30490 UBERON:0007641 trigeminal nuclear complex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007641 nuclei trigemini|trigeminal nuclei The sensory trigeminal nerve nuclei are the largest of the cranial nerve nuclei, and extend through the whole of the midbrain, pons and medulla. There is also a distinct trigeminal motor nucleus that is medial to the chief sensory nucleus[WP]. CHEBI:136852 adlupulone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136852 CHEBI:136851 colupulone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136851 CHEBI:136858 beta-D-Delta(4)-GlcpA-(1->4)-beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-D-Glcp biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136858 CHEBI:136857 N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136857 CHEBI:136856 O-succinyl-L-serinate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136856 CHEBI:78433 refrigerant biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78433 UBERON:0007647 ectomeninx biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007647 future dura mater The outermost layer of the mesenchymal capsule that surrounds the developing brain, of mixed paraxial mesoderm and neural crest origin. The ectomeninx forms the dura mater (both inner layer and outer chondrogenic layer). CHEBI:78430 1,2-diacyl-3-(3-O-sulfo-beta-D-galactosyl)glycerol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78430 UBERON:0007646 endomeninx biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007646 future leptomeninx|future leptomeninges The innermost layer of the mesenchymal capsule that surrounds the developing brain, primarily of neural crest origin. The endomeninx forms the leptomeninx. CHEBI:78437 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78437 CHEBI:136850 2-acyl-4,6-diprenylphloroglucinol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136850 UBERON:0007645 future meninx biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007645 primordial meninx|primary meninx|meninx primitiva|primitive meninx A developing mesenchymal capsule that covers the developing brain and spinal cord and is the precursor of the meningeal cluster. In mammals this gives rise to the arachnoid mater, pia mater and dura mater. In cyclostomes and fishes, the future meninx gives rise to a single meningeal layer, the primitive meninx. CHEBI:78436 ganglioside GD3(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78436 UBERON:0007644 thoracic lymph node biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007644 deep thoracic lymph node|lymph node of thorax A lymph node that is part of a thorax. Includes lymph nodes of the lungs and mediastinal lymph nodes CHEBI:78435 [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n-diphospho-ditrans,polycis-undecaprenol polyanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78435 CHEBI:30492 dioxidaniumyl biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30492 CHEBI:78449 O-(S-malonylpantetheine-4'-phosphoryl)serine(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78449 CHEBI:136829 1-aci-nitro-2-(phenyl)ethane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136829 CHEBI:136828 4'-O-methylxanthohumol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136828 CHEBI:29476 3-amino-4-hydroxybenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29476 CHEBI:136826 xanthogalenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136826 CHEBI:29472 2-heptyl-3-hydroxy-4-quinolone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29472 CHEBI:29474 (S)-3,5-dihydroxyphenylglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29474 GO:0042703 menstruation biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0042703 Wikipedia:Menstruation The cyclic, physiologic discharge through the vagina of blood and endometrial tissues from the nonpregnant uterus. CHEBI:136821 RNA polyanion nucleotide 2'-phosphate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136821 CHEBI:136820 RNA polyanion 2',3'-cyclic phosphate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136820 GO:0042702 uterine wall growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042702 The regrowth of the endometrium and blood vessels in the uterus following menstruation, resulting from a rise in progesterone levels. GO:0042705 ocellus photoreceptor cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042705 The process in which a relatively unspecialized cell acquires specialized features of a photoreceptor cell found in the ocellus. GO:0042704 uterine wall breakdown biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042704 The sloughing of the endometrium and blood vessels during menstruation that results from a drop in progesterone levels. CHEBI:136825 (E)-1-(glycyl-L-cystein-S-yl)-omega-(methylthio)alkylhydroximate zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136825 CHEBI:136824 mandelamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136824 CHEBI:136823 alpha-D-Glcp-(1->6)-alpha-D-Glcp-(1->3)-alpha-D-Glcp-(1->6)-D-Glcp biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136823 GO:0042701 progesterone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042701 The regulated release of progesterone, a steroid hormone, by the corpus luteum of the ovary and by the placenta. GO:0042700 luteinizing hormone signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042700 luteinizing hormone signalling pathway The series of molecular signals mediated by luteinizing hormone. CHEBI:136822 cyclobis-(1->6)-alpha-nigerosyl biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136822 CHEBI:78444 EC 3.1.1.1 (carboxylesterase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78444 CHEBI:30465 tellurous acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30465 CHEBI:78442 AMP 3'-end(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78442 GO:0042707 ocellus photoreceptor cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042707 The process in which the developmental fate of a cell becomes restricted such that it will develop into photoreceptor cell in the ocellus. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments. UBERON:0007635 nucleus of medulla oblongata biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007635 A neural nucleus that is part of a medulla oblongata. GO:0042706 eye photoreceptor cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042706 The process in which the developmental fate of a cell becomes restricted such that it will develop into an eye photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments. CHEBI:78447 alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78447 GO:0042709 succinate-CoA ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042709 A heterodimeric enzyme complex, usually composed of an alpha and beta chain. Functions in the TCA cycle, hydrolyzing succinyl-CoA into succinate and CoA, thereby forming ATP or GTP. CHEBI:78446 O-(S-acetylpantetheine-4'-phosphoryl)serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78446 GO:0042708 obsolete elastase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042708 elastase activity OBSOLETE. Catalysis of the hydrolysis of elastin. CHEBI:78445 alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)-[alpha-N-acetylneuraminosyl-(2->3)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphingosine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78445 CL:1000909 kidney loop of Henle epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000909 UBERON:0007619 limiting membrane of retina biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007619 retina lamina CHEBI:29484 (S)-4,5-dihydroxypentane-2,3-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29484 CHEBI:136832 Cys(IAN)-Gly zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136832 GO:0042714 dosage compensation complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042714 The aggregation, arrangement and bonding together of proteins on DNA or RNA to form the complex that mediates dosage compensation on one or more X chromosomes. CHEBI:29491 5-O-beta-D-mycaminosyltylactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29491 GO:0042713 sperm ejaculation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042713 The expulsion of seminal fluid, thick white fluid containing spermatozoa, from the male genital tract. CHEBI:136831 S-[(E)-N-hydroxy-2-(indol-3-yl)ethanimidoyl]-L-cysteinylglycine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136831 GO:0042716 plasma membrane-derived chromatophore biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042716 chromatophore vesicle A pigment-bearing structure that is derived from the cytoplasmic membrane, sometimes consisting of simple invaginations and sometimes a complete vesicle. This component is found in certain photosynthetic bacteria and cyanobacteria. CHEBI:136830 S-[(Z)-N-hydroxy-2-phenylethanimidoyl]-L-cysteinylglycine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136830 GO:0042715 dosage compensation complex assembly involved in dosage compensation by hypoactivation of X chromosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042715 dosage compensation complex assembly during dosage compensation by hypoactivation of X chromosome The aggregation, arrangement and bonding together of proteins on DNA to form the complex that mediates dosage compensation on both X chromosomes in the monogametic sex, ultimately resulting in a two-fold reduction in transcription from these chromosomes. An example of this process is found in Caenorhabditis elegans. CHEBI:78451 O-[S-(3R)-hydroxybutanoylpantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78451 GO:0042710 biofilm formation biolink:BiologicalProcess go-plus goslim_candida|gocheck_do_not_manually_annotate|gocheck_do_not_annotate|goslim_pir http://purl.obolibrary.org/obo/GO_0042710 A process in which planktonically growing microorganisms grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription. CHEBI:78450 O-(S-acetoacetylpantetheine-4'-phosphoryl)serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78450 CHEBI:136834 2-sulfenohercynine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136834 GO:0042712 paternal behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042712 paternal behaviour Male behaviors associated with the care and rearing offspring. CHEBI:136833 glycolaldehyde triphosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136833 GO:0042711 maternal behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042711 maternal behaviour Female behaviors associated with the care and rearing of offspring. CHEBI:30477 tellurite biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30477 CHEBI:78455 alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer(d18:1)(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78455 CHEBI:78454 O-(S-butanoylpantetheine-4'-phosphoryl)serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78454 CHEBI:78453 O-[S-(2E)-butenoylpantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78453 CHEBI:78452 alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78452 UBERON:0007625 pigment epithelium of eye biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007625 eye pigment epithelium epithelial layer of the retina, ciliary body, or iris composed of cells containing pigment granules. CHEBI:78459 O-(S-hexanoylpantetheine-4'-phosphoryl)serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78459 GO:0042718 yolk granule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042718 Discrete structures that partition the water-insoluble portion of the yolk of oocytes and ova, which may or may not be membrane enclosed. GO:0042717 plasma membrane-derived chromatophore membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042717 The lipid bilayer associated with a plasma membrane-derived chromatophore; surrounds chromatophores that form complete vesicles. CHEBI:78458 O-[S-(2E)-hexenoylpantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78458 CHEBI:78457 O-[S-(3R)-hydroxyhexanoylpantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78457 CHEBI:78456 O-(S-3-oxohexanoylpantetheine-4'-phosphoryl)serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78456 GO:0042719 mitochondrial intermembrane space protein transporter complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042719 Tim9-Tim10 complex Soluble complex of the mitochondrial intermembrane space composed of various combinations of small Tim proteins; acts as a protein transporter to guide proteins to the Tim22 complex for insertion into the mitochondrial inner membrane. CHEBI:30449 validamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30449 CHEBI:29457 (5Z,7E,9E,14Z,17Z)-icosapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29457 GO:0042725 thiamine-containing compound catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042725 thiamin and derivative catabolic process|thiamin and derivative catabolism|thiamine-containing compound catabolism|thiamine and derivative catabolism|vitamin B1 and derivative catabolism|thiamine-containing compound degradation|thiamin-containing compound catabolic process|thiamine-containing compound breakdown|vitamin B1 and derivative catabolic process|thiamine and derivative catabolic process The chemical reactions and pathways resulting in the breakdown of thiamine (vitamin B1), and compounds derived from it. GO:0042724 thiamine-containing compound biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042724 thiamine-containing compound anabolism|thiamine-containing compound synthesis|thiamin and derivative biosynthesis|thiamin and derivative biosynthetic process|thiamine-containing compound formation|thiamine-containing compound biosynthesis|thiamine and derivative biosynthetic process|thiamine and derivative biosynthesis|vitamin B1 and derivative biosynthetic process|vitamin B1 and derivative biosynthesis|thiamin-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), and related compounds. GO:0042727 flavin-containing compound biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042727 flavin-containing compound anabolism|flavin-containing compound synthesis|flavin-containing compound formation|flavin-containing compound biosynthesis|riboflavin and derivative biosynthetic process|riboflavin and derivative biosynthesis|vitamin B2 and derivative biosynthetic process|vitamin B2 and derivative biosynthesis The chemical reactions and pathways resulting in the formation of a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position. GO:0042726 flavin-containing compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042726 flavin-containing compound metabolism|riboflavin and derivative metabolism|vitamin B2 and derivative metabolism|vitamin B2 and derivative metabolic process|riboflavin and derivative metabolic process The chemical reactions and pathways involving a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position. CHEBI:78462 O-[S-(2E)-octenoylpantetheine-4-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78462 GO:0042721 TIM22 mitochondrial import inner membrane insertion complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042721 mitochondrial inner membrane protein insertion complex|mitochondrial protein translocase complex|Tim22 complex A multi-subunit complex embedded in the mitochondrial inner membrane that mediates the inner membrane insertion of multi-transmembrane spanning proteins that contain internal targeting elements. In yeast cells, TIM22 is a 300-kDa complex, consisting of four membrane integral subunits, Tim22, Tim54, Tim18 and Sdh3, and a peripheral chaperone complex consisting of the small TIM proteins, Tim9-Tim10-Tim12. UBERON:0007692 nucleus of thalamus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007692 nuclear complex of thalamus|thalamic nucleus A nucleus of brain that is part of a thalamus. GO:0042720 mitochondrial inner membrane peptidase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042720 IMP|mitochondrion inner membrane peptidase complex Protease complex of the mitochondrial inner membrane, consisting of at least two subunits, involved in processing of both nuclear- and mitochondrially-encoded proteins targeted to the intermembrane space. CHEBI:78461 O-[S-(3R)-hydroxyoctanoylpantetheine-4-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78461 GO:0042723 thiamine-containing compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042723 thiamin and derivative metabolism|thiamine-containing compound metabolism|thiamin-containing compound metabolic process|thiamine and derivative metabolism|vitamin B1 and derivative metabolism|vitamin B1 and derivative metabolic process|thiamine and derivative metabolic process|thiamin and derivative metabolic process The chemical reactions and pathways involving thiamine (vitamin B1), and compounds derived from it. CHEBI:78460 O-(S-3-oxooctanoylpantetheine-4-phosphoryl)serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78460 UBERON:0007691 gustatory pore biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007691 taste pore|porus gustatorius The minute opening of a taste bud on the surface of the oral mucosa through which the gustatory hairs of the specialised neuroepithelial gustatory cells project. UBERON:0007690 early pharyngeal endoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007690 pharyngeal endoderm|pharyngeal region endoderm|early pharyngeal arch endoderm|pharyngeal arch endoderm . GO:0042722 alpha-beta T cell activation by superantigen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042722 alpha-beta T-lymphocyte activation by superantigen|alpha-beta T-cell activation by superantigen|alpha-beta T lymphocyte activation by superantigen The change in morphology and behavior of alpha-beta T cells resulting from exposure to a superantigen, a microbial antigen with an extremely potent activating effect on T cells that bear a specific variable region. CHEBI:78466 O-[S-(3R)-hydroxydecanoylpantetheine-4-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78466 CHEBI:78464 O-(S-3-oxodecanoylpantetheine-4-phosphoryl)serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78464 CHEBI:78463 O-(S-octanoylpantetheine-4-phosphoryl)serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78463 GO:0042729 DASH complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042729 Duo1p-Dam1p-Dad1p complex|condensed nuclear chromosome kinetochore-associated DASH complex|DDD complex|Dam1 complex A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1p. The complex forms part of the kinetochore, associates with microtubules when the kinetochore attaches to the spindle, and plays a role in spindle attachment, chromosome segregation and spindle stability. CHEBI:78469 O-(S-3-oxododecanoylpantetheine-4-phosphoryl)serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78469 GO:0042728 flavin-containing compound catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042728 riboflavin and derivative catabolic process|flavin-containing compound catabolism|riboflavin and derivative catabolism|vitamin B2 and derivative catabolism|flavin-containing compound catabolic process degradation|flavin-containing compound catabolic process breakdown|vitamin B2 and derivative catabolic process The chemical reactions and pathways resulting in the breakdown of a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position. UBERON:0007699 tract of spinal cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007699 spinal cord tract An axon tract that is part of a spinal cord. CHEBI:78468 O-(S-decanoylpantetheine-4-phosphoryl)serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78468 CHEBI:78467 O-[S-(2E)-decenoylpantetheine-4-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78467 GO:0042730 fibrinolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042730 Wikipedia:Fibrinolysis A process that solubilizes fibrin in the bloodstream of a multicellular organism, chiefly by the proteolytic action of plasmin. CHEBI:29461 10-deoxymethynolide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29461 CHEBI:136819 5-hydroxyoctadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136819 GO:0042736 NADH kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042736 KEGG_REACTION:R00105|EC:2.7.1.86|RHEA:12260|MetaCyc:NADH-KINASE-RXN DPNH kinase activity|reduced diphosphopyridine nucleotide kinase activity|reduced nicotinamide adenine dinucleotide kinase (phosphorylating)|ATP:NADH 2'-phosphotransferase activity Catalysis of the reaction: ATP + NADH = ADP + 2 H(+) + NADPH. CHEBI:136810 12-hydroxyjasmonates biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136810 UBERON:0007685 region of nephron tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007685 renal tubule region|region of renal tubule GO:0042735 protein body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042735 A membrane-bounded plant organelle found in the developing endosperm, contains storage proteins. GO:0042738 exogenous drug catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042738 exogenous drug degradation|exogenous drug breakdown|exogenous drug catabolism The chemical reactions and pathways resulting in the breakdown of a drug that has originated externally to the cell or organism. UBERON:0007684 uriniferous tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007684 functional unit of the kidney that forms urine, consisting of two parts, the nephron and the collecting tubule. GO:0042737 drug catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042737 drug catabolism|drug degradation|drug breakdown The chemical reactions and pathways resulting in the breakdown of a drug, a substance used in the diagnosis, treatment or prevention of a disease. CHEBI:78473 O-(S-3-oxotetradecanoylpantetheine-4-phosphoryl)serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78473 GO:0042732 D-xylose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042732 D-xylose metabolism The chemical reactions and pathways involving D-xylose, a naturally occurring plant polysaccharide. GO:0042731 PH domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042731 Interacting selectively and non-covalently with a PH domain (pleckstrin homology) of a protein, a domain of about 100 residues that occurs in a wide range of proteins involved in intracellular signaling or as constituents of the cytoskeleton. CHEBI:136813 11-sulfojasmonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136813 CHEBI:78472 O-[S-(2E)-dodecenoylpantetheine-4-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78472 GO:0042734 presynaptic membrane biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0042734 pre-synaptic membrane|presynaptic plasma membrane A specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction; many synaptic junctions exhibit structural presynaptic characteristics, such as conical, electron-dense internal protrusions, that distinguish it from the remainder of the axon plasma membrane. CHEBI:136812 11-hydroxyjasmonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136812 GO:0042733 embryonic digit morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042733 The process, occurring in the embryo, by which the anatomical structures of the digit are generated and organized. A digit is one of the terminal divisions of an appendage, such as a finger or toe. CHEBI:136811 12-sulfojasmonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136811 CHEBI:78470 O-[S-(3R)-hydroxydodecanoylpantetheine-4-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78470 CHEBI:78477 O-(S-tetradecanoylpantetheine-4'-phosphoryl)serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78477 CHEBI:78475 O-[S-(2E)-tetradecenoylpantetheine-4-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78475 CHEBI:78474 O-[S-(3R)-hydroxytetradecanoylpantetheine-4-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78474 CHEBI:30452 tellurium atom biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30452 GO:0042739 endogenous drug catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042739 endogenous drug degradation|endogenous drug breakdown|endogenous drug catabolism The chemical reactions and pathways resulting in the breakdown of a drug that has originated internally within the cell or organism. UBERON:0007689 thyroid diverticulum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007689 saccus thyroideus|diverticulum thyroideum endodermal bud derived from the endodermal epithelium of the embryonic pharyngeal floor[MP]. The thyroid diverticulum is the embryological structure from which thyroid follicular cells derive. It grows from the floor of the pharnyx[WP]. UBERON:0007688 anlage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007688 future organ|field|organ field|developmental field Anlagen are populations of contiguous cells, typically arranged in one plane, that are morphologically indistinct, but that already correspond in extent to a later organ/tissue. UBERON:0007687 kidney field biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007687 kidney anlage region of the embryo into the area in which the kidney rudiment will develop. CHEBI:78478 O-(S-3-oxohexadecanoylpantetheine-4'-phosphoryl)serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78478 CHEBI:29438 methanide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29438 GO:0042741 endogenous antibiotic catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042741 endogenous antibiotic degradation|endogenous antibiotic breakdown|endogenous antibiotic catabolism The chemical reactions and pathways resulting in the breakdown of an antibiotic that has originated internally within the cell or organism. CHEBI:29435 carbide(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29435 GO:0042740 exogenous antibiotic catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042740 exogenous antibiotic catabolism|exogenous antibiotic degradation|exogenous antibiotic breakdown The chemical reactions and pathways resulting in the breakdown of an antibiotic that has originated externally to the cell or organism. CHEBI:29434 carbide(4-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29434 GO:0042747 circadian sleep/wake cycle, REM sleep biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042747 A stage in the circadian sleep cycle during which dreams occur and the body undergoes marked changes including rapid eye movement, loss of reflexes, and increased pulse rate and brain activity. CHEBI:78480 O-[S-(3R)-hydroxyhexadecanoylpantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78480 GO:0042746 circadian sleep/wake cycle, wakefulness biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042746 The part of the circadian sleep/wake cycle where the organism is not asleep. GO:0042749 regulation of circadian sleep/wake cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042749 Any process that modulates the frequency, rate or extent of the circadian sleep/wake cycle. GO:0042748 circadian sleep/wake cycle, non-REM sleep biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042748 All sleep stages in the circadian sleep/wake cycle other than REM sleep. These stages are characterized by a slowing of brain waves and other physiological functions. CHEBI:78484 beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-stearoylsphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78484 GO:0042743 hydrogen peroxide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042743 H2O2 metabolic process|hydrogen peroxide metabolism The chemical reactions and pathways involving hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA. CHEBI:78483 O-(S-hexadecanoylpantetheine-4'-phosphoryl)serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78483 GO:0042742 defense response to bacterium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042742 defense response to bacterium, incompatible interaction|defense response to bacteria|resistance response to pathogenic bacterium|defence response to bacterium|resistance response to pathogenic bacteria|defence response to bacteria|antibacterial peptide activity Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism. GO:0042745 circadian sleep/wake cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042745 The cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm. CHEBI:78482 N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosylceramide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78482 GO:0042744 hydrogen peroxide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042744 hydrogen peroxide scavenging|hydrogen peroxide catabolism|hydrogen peroxide removal|hydrogen peroxide degradation|H2O2 scavenging|H2O2 catabolic process|detoxification of hydrogen peroxide|hydrogen peroxide breakdown|detoxification of H2O2 The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2). CHEBI:78481 O-[S-(2E)-hexadecenoylpantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78481 CHEBI:78488 O-[S-(3R)-hydroxyoctadecanoylpantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78488 CHEBI:78487 O-(S-3-oxooctadecanoylpantetheine-4'-phosphoryl)serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78487 CHEBI:78486 N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-stearoylsphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78486 CHEBI:78485 ganglioside GM2 (18:0) (1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78485 CHEBI:78489 O-[S-(2E)-octadecenoylpantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78489 CHEBI:30436 tetrahydropterin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30436 CHEBI:29449 hydrogen azide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29449 GO:0042750 hibernation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042750 Wikipedia:Hibernation Any process in which an organism enters and maintains a period of dormancy in which to pass the winter. It is characterized by narcosis and by sharp reduction in body temperature and metabolic activity and by a depression of vital signs. GO:0042752 regulation of circadian rhythm biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042752 Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours. GO:0042751 estivation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042751 Wikipedia:Estivation aestivation Any process in which an organism enters and maintains a period of dormancy, similar to hibernation, but that occurs during the summer. It insulates against heat to prevent the harmful effects of the season. GO:0042758 long-chain fatty acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042758 long-chain fatty acid breakdown|long-chain fatty acid catabolism|long-chain fatty acid degradation The chemical reactions and pathways resulting in the breakdown of long-chain fatty acids, a fatty acid with a chain length between C13 and C22. GO:0042757 giant axon biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042757 Extremely large, unmyelinated axon found in invertebrates. Has high conduction speeds and is usually involved in panic or escape responses. GO:0042759 long-chain fatty acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042759 long-chain fatty acid anabolism|long-chain fatty acid synthesis|long-chain fatty acid formation|long-chain fatty acid biosynthesis The chemical reactions and pathways resulting in the formation of long-chain fatty acids, any fatty acid with a chain length between C13 and C22. GO:0042754 negative regulation of circadian rhythm biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042754 downregulation of circadian rhythm|down regulation of circadian rhythm|inhibition of circadian rhythm|down-regulation of circadian rhythm Any process that stops, prevents, or reduces the frequency, rate or extent of a circadian rhythm behavior. CHEBI:78495 O-(S-octadecanoylpantetheine-4'-phosphoryl)serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78495 GO:0042753 positive regulation of circadian rhythm biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042753 upregulation of circadian rhythm|stimulation of circadian rhythm|up-regulation of circadian rhythm|activation of circadian rhythm|up regulation of circadian rhythm Any process that activates or increases the frequency, rate or extent of a circadian rhythm behavior. CHEBI:78494 3'-(L-leucyl)adenylyl zwitterionic group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78494 GO:0042756 drinking behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042756 drinking behaviour The specific behavior of an organism relating to the intake of liquids, especially water. GO:0042755 eating behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042755 eating behaviour The specific behavior of an organism relating to the intake of food, any substance (usually solid) that can be metabolized by an organism to give energy and build tissue. CHEBI:78499 C-terminal-gamma-L-glutamyl-L-2-aminoadipate 6-phosphate(4-) group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78499 CHEBI:78497 3'-(L-alanyl)adenylyl zwitterionic group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78497 GO:0003157 endocardium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003157 The process whose specific outcome is the progression of the endocardium over time, from its formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. GO:0003156 regulation of animal organ formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003156 Any process that modulates the rate, frequency or extent of animal organ formation. Organ formation is the process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. GO:0003159 morphogenesis of an endothelium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003159 The process in which the anatomical structure of an endothelium is generated and organized. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells. GO:0003158 endothelium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003158 The process whose specific outcome is the progression of an endothelium over time, from its formation to the mature structure. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells. GO:0003153 closure of embryonic heart tube biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003153 Creation of the central hole of the embryonic heart tube by sealing the edges of an epithelial fold. GO:0003152 morphogenesis of an epithelial fold involved in embryonic heart tube formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003152 The morphogenetic process in which an epithelial sheet bends along a linear axis, contributing to embryonic heart tube formation. GO:0003155 BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003155 BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that contributes to the determination of lateral mesoderm left/right asymmetry. GO:0003154 BMP signaling pathway involved in determination of left/right symmetry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003154 BMP signaling pathway involved in determination of left/right asymmetry|BMP signalling pathway involved in determination of left/right symmetry A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the determination of left/right symmetry. GO:0003151 outflow tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003151 The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries. GO:0003150 muscular septum morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003150 The process in which the muscular septum is generated and organized. The muscular septum is the lower part of the ventricular septum. GO:0003168 Purkinje myocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003168 cardiac Purkinje fiber cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a Purkinje myocyte (also known as cardiac Purkinje fiber cell). These cells are specialized cardiomyocytes that receive signals from the bundle of His and innervate the ventricular cardiac muscle. GO:0003167 atrioventricular bundle cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003167 AV bundle cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the atrioventricular bundle. These cells are specialized cardiomyocytes that transmit signals from the AV node to the cardiac Purkinje fibers. GO:0003169 coronary vein morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003169 The process in which the anatomical structures of veins of the heart are generated and organized. GO:0003164 His-Purkinje system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003164 The process whose specific outcome is the progression of the His-Purkinje system over time, from its formation to the mature structure. The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles. GO:0003163 sinoatrial node development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003163 SAN development|SA node development|sinus node development The process whose specific outcome is the progression of the sinoatrial (SA) node over time, from its formation to the mature structure. The SA node is part of the cardiac conduction system that controls the timing of heart muscle contraction. It relays electrical signals to the AV node. GO:0003166 bundle of His development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003166 atrioventricular bundle development The process whose specific outcome is the progression of the bundle of His over time, from its formation to the mature structure. The bundle of His is part of the His-Purkinje system that transmits signals from the AV node to the cardiac Purkinje fibers. GO:0003165 Purkinje myocyte development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003165 cardiac Purkinje fiber development The process whose specific outcome is the progression of a Purkinje myocyte over time, from its formation to the mature structure. The Purkinje myocyte (also known as cardiac Purkinje fiber) is part of the cardiac conduction system that receives signals from the bundle of His and innervates the ventricular cardiac muscle. GO:0003160 endocardium morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003160 The process in which the anatomical structure of the endocardium is generated and organized. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. GO:0003162 atrioventricular node development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003162 AV node development The process whose specific outcome is the progression of the atrioventricular (AV) node over time, from its formation to the mature structure. The AV node is part of the cardiac conduction system that controls the timing of ventricle contraction by receiving electrical signals from the sinoatrial (SA) node and relaying them to the His-Purkinje system. GO:0003161 cardiac conduction system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003161 heart conduction system development|cardiac impulse conducting system development The process whose specific outcome is the progression of the cardiac conduction system over time, from its formation to the mature structure. The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat. GO:0003139 secondary heart field specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003139 SHF specification|anterior heart field specification|second heart field specification The process that results in the delineation of a specific region of the lateral mesoderm into the area which will form the majority of the mesodermal component of the right ventricle, arterial pole (outflow tract) and venous pole (inflow tract). GO:0003138 primary heart field specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003138 FHS specification|first heart field specification The process that results in the delineation of a specific region of the lateral mesoderm into the area which will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle. GO:0003135 fibroblast growth factor receptor signaling pathway involved in heart induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003135 fibroblast growth factor receptor signalling pathway involved in heart induction The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to heart induction. GO:0003134 endodermal-mesodermal cell signaling involved in heart induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003134 endodermal-mesodermal cell signalling involved in heart induction Any process that mediates the transfer of information from endodermal cells to mesodermal cells that contributes to heart induction. GO:0003137 Notch signaling pathway involved in heart induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003137 Notch signalling pathway involved in heart induction The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to heart induction. GO:0003136 negative regulation of heart induction by canonical Wnt signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003136 negative regulation of cardioblast cell fate specification by Wnt receptor signaling pathway|negative regulation of heart induction by canonical Wnt receptor signalling pathway|negative regulation of heart induction by canonical Wnt receptor signaling pathway|negative regulation of heart induction by canonical Wnt-activated signaling pathway Any canonical Wnt signaling that decreases the rate, frequency or extent of heart induction. GO:0003131 mesodermal-endodermal cell signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003131 mesodermal-endodermal cell signalling Any process that mediates the transfer of information from mesodermal cells to endodermal cells. GO:0003130 BMP signaling pathway involved in heart induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003130 BMP signalling pathway involved in heart induction A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to heart induction. GO:0003133 endodermal-mesodermal cell signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003133 endodermal-mesodermal cell signalling Any process that mediates the transfer of information from endodermal cells to mesodermal cells. GO:0003132 mesodermal-endodermal cell signaling involved in heart induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003132 mesodermal-endodermal cell signalling involved in heart induction Any process that mediates the transfer of information from mesodermal cells to endodermal cells that contributes to heart induction. GO:0003149 membranous septum morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003149 The process in which the membranous septum is generated and organized. The membranous septum is the upper part of ventricular septum. GO:0003146 heart jogging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003146 cardiac jogging The morphogenetic process in which the heart cone is displaced to the left with respect to the vector of the anterior-posterior axis. GO:0003145 embryonic heart tube formation via epithelial folding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003145 The process that gives rise to the embryonic heart tube by the cells of the heart field along a linear axis. GO:0003148 outflow tract septum morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003148 The process in which the anatomical structures of the outflow tract septum are generated and organized. The outflow tract septum is a partition in the outflow tract. GO:0003147 neural crest cell migration involved in heart formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003147 The characteristic movement of a cell from the dorsal ridge of the neural tube towards the heart and that contributes to heart formation. GO:0003142 cardiogenic plate morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003142 cardiac crescent morphogenesis The process in which the anatomical structures of the cardiogenic plate are generated and organized. The cardiogenic plate is the first recognizable structure derived from the heart field. GO:0003141 obsolete transforming growth factor beta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003141 transforming growth factor beta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry|TGFbeta receptor signalling pathway involved in determination of lateral mesoderm left/right asymmetry|TGF-beta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry|TGF-beta receptor signalling pathway involved in determination of lateral mesoderm left/right asymmetry|TGFbeta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry|transforming growth factor beta receptor signalling pathway involved in determination of lateral mesoderm left/right asymmetry|transforming growth factor beta receptor signaling pathway involved in lateral mesoderm left/right asymmetry determination OBSOLETE. The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands that contributes to lateral mesoderm left/right asymmetry determination. GO:0003144 embryonic heart tube formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003144 The process that gives rise to the embryonic heart tube. This process pertains to the initial formation of a structure from unspecified parts. The embryonic heart tube is an epithelial tube that will give rise to the mature heart. GO:0003143 embryonic heart tube morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003143 The process in which the anatomical structures of the embryonic heart tube are generated and organized. The embryonic heart tube is an epithelial tube that will give rise to the mature heart. GO:0003140 determination of left/right asymmetry in lateral mesoderm biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003140 The establishment of the lateral mesoderm with respect to the left and right halves. GO:0003117 regulation of vasoconstriction by circulating norepinephrine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003117 regulation of vasoconstriction by circulating noradrenaline Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of norepinephrine into the bloodstream. GO:0003116 regulation of vasoconstriction by norepinephrine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003116 Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of norepinephrine into the bloodstream or released by nerve endings. GO:0003119 regulation of vasoconstriction by neuronal epinephrine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003119 regulation of vasoconstriction by neuronal adrenaline Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of epinephrine released by nerve endings. GO:0003118 regulation of vasoconstriction by neuronal norepinephrine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003118 regulation of vasoconstriction by neuronal noradrenaline Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of norepinephrine released by nerve endings. GO:0003113 positive regulation of heart rate by neuronal norepinephrine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003113 positive regulation of heart rate by neuronal noradrenaline The process in which the secretion of norepinephrine released from nerve endings increases the rate of heart muscle contraction. GO:0003112 positive regulation of heart rate by neuronal epinephrine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003112 positive regulation of heart rate by neuronal adrenaline The process in which the secretion of epinephrine from nerve endings increases the rate of heart muscle contraction. GO:0003115 regulation of vasoconstriction by epinephrine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003115 Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of epinephrine into the bloodstream or released by nerve endings. GO:0003114 positive regulation of heart rate by circulating norepinephrine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003114 positive regulation of heart rate by circulating noradrenaline The process in which the secretion of norepinephrine into the bloodstream increases the rate of heart muscle contraction. GO:0003111 positive regulation of heart rate by circulating epinephrine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003111 positive regulation of heart rate by circulating adrenaline The process in which the secretion of epinephrine into the bloodstream increases the rate of heart muscle contraction. GO:0003110 positive regulation of the force of heart contraction by neuronal norepinephrine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003110 increased force of heart contraction by neuronal noradrenaline|increased force of heart contraction by neuronal norepinephrine The process in which the release of norepinephrine from nerve endings modulates the force of heart muscle contraction. CHEBI:136887 nickel-sirohydrochlorin a,c-diamide(6-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136887 CHEBI:136886 16-epiestriol 16-O-(beta-D-glucuronide)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136886 CHEBI:136885 16-epiestriol 3-O-(beta-D-glucuronide)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136885 CHEBI:136884 17-epiestriol 16-O-(beta-D-glucuronide)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136884 CHEBI:136889 5beta steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136889 CHEBI:136888 15,17(3)-seco-F430-17(3)-acid(6-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136888 UBERON:0007617 synovial cavity of joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007617 cavitas articularis (junctura synovialis)|cavity of synovial joint|synovial cavity|joint cavity|articular cavity (synovial joint) An anatomical cavity that surrounded_by a synovial joint. UBERON:0007616 layer of synovial tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007616 synovial membrane|synovium|stratum synoviale|synovial layer|synovial tissue A thin, loose vascular connective tissue that makes up the membranes surrounding joints and the sheaths protecting tendons (particularly flexor tendons in the hands and feet) where they pass over bony prominences. Synovial tissue contains synovial cells, which secrete a viscous liquid called synovial fluid; this liquid contains protein and hyaluronic acid and serves as a lubricant and nutrient for the joint cartilage surfaces[BTO]. Synovial tissue can be found in tendons (tissues that connect muscle to bone), bursae (fluid-filled, cushioning sacs found in spaces between tendons, ligaments, and bones), and the cavity (hollow enclosed area) that separates the bones of a freely movable joint, such as the knee or elbow[BTO]. CHEBI:136883 17-epiestriol 17-O-(beta-D-glucuronide)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136883 CHEBI:136882 17-epiestriol 3-O-(beta-D-glucuronide)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136882 CHEBI:136881 3-carboxy-3-hydroxypropanoyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136881 GO:0003128 heart field specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003128 The process that results in the delineation of a specific region of the lateral mesoderm into the area in which the heart will develop. GO:0003127 detection of nodal flow biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003127 The series of events by which an endogenous stimulus is received by a cilium on a cell and converted to a molecular signal contributing to left/right asymmetry. GO:0003129 heart induction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003129 The close range interaction between mesoderm and endoderm or ectoderm that causes cells to change their fates and specify the development of the heart. GO:0003124 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003124 GO:0003123 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003123 GO:0003126 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003126 GO:0003125 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003125 GO:0003120 regulation of vasoconstriction by circulating epinephrine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003120 regulation of vasoconstriction by circulating adrenaline Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of epinephrine into the bloodstream. GO:0003122 norepinephrine-mediated vasodilation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003122 regulation of vasodilation by circulating noradrenaline|regulation of vasodilation by noradrenaline|regulation of vasodilation by neuronal noradrenaline|regulation of vasodilation by neuronal norepinephrine|regulation of vasodilation by norepinephrine|regulation of vasodilation by circulating norepinephrine A vasodilation process resulting from secretion of norepinephrine into the bloodstream or released by nerve endings. GO:0003121 epinephrine-mediated vasodilation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003121 regulation of vasodilation by neuronal adrenaline|regulation of vasodilation by adrenaline|regulation of vasodilation by circulating adrenaline|regulation of vasodilation by circulating epinephrine|regulation of vasodilation by epinephrine|regulation of vasodilation by neuronal epinephrine A vasodilation process resulting from secretion of epinephrine into the bloodstream or released by nerve endings. CHEBI:136897 O-[S-(3S)-hydroxy-3-methylglutarylpantetheine-4'-phosphoryl]-L-serine(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136897 CHEBI:136896 5'-(5'-triphosphoguanosine)-(purine-ribonucleotide)(3-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136896 CHEBI:136895 dTDP-L-rhamnose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136895 CHEBI:136899 chenodeoxycholic acid 24-O-(beta-D-glucuronide)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136899 CHEBI:136890 3-dimethylallyl-4-hydroxymandelate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136890 UBERON:0007601 ciliated epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007601 Epithelium bearing vibratile cilia on the free surface. CHEBI:136891 2'-unsubstituted isoflavones biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136891 CHEBI:136860 antidote to sarin poisoning biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136860 CHEBI:78402 1-oleyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78402 CHEBI:78419 1-(Z)-alk-1-enyl-2-acetyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78419 GO:0003106 negative regulation of glomerular filtration by angiotensin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003106 angiotensin-mediated regulation of glomerular filtration|regulation of glomerular filtration by angiotensin The process in which angiotensin directly decreases the rate of glomerular filtration in the kidney. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule. GO:0003105 negative regulation of glomerular filtration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003105 Any process that stops, prevents, or reduces the frequency, rate or extent of glomerular filtration. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule. GO:0003108 negative regulation of the force of heart contraction by chemical signal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003108 negative regulation of the force of heart muscle contraction by chemical signal Any process which decreases the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine. GO:0003107 obsolete positive regulation of natriuresis by angiotensin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003107 positive regulation of natriuresis by angiotensin|angiotensin-mediated positive regulation of natriuresis OBSOLETE. The process in which angiotensin increases the rate of natriuresis indirectly via diuresis. Natriuresis is the process of renal sodium excretion. GO:0003102 obsolete positive regulation of diuresis by angiotensin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003102 angiotensin-mediated positive regulation of diuresis|positive regulation of diuresis by angiotensin OBSOLETE. Any process mediated by angiotensin that increases the rate of diuresis. GO:0003101 regulation of systemic arterial blood pressure by circulatory epinephrine-norepinephrine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003101 regulation of blood pressure by circulating adrenaline-noradrenaline The process in which epinephrine-norepinephrine modulate the force with which blood passes through the circulatory system. GO:0003104 positive regulation of glomerular filtration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003104 Any process that activates or increases the frequency, rate or extent of glomerular filtration. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule. GO:0003103 obsolete positive regulation of diuresis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003103 positive regulation of diuresis OBSOLETE. Any process that activates or increases the frequency, rate or extent of diuresis. Diuresis is the process of renal water excretion. GO:0003100 regulation of systemic arterial blood pressure by endothelin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003100 The process in which endothelin modulates the force with which blood passes through the circulatory system. Endothelin is a hormone that is released by the endothelium, and it is a vasoconstrictor. CHEBI:136876 1-(3,4-dihydroxybenzoyl)-beta-D-glucopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136876 CHEBI:136875 oligoglycosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136875 CHEBI:136873 oligoglycosyl-(1->4)-beta-D-glucose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136873 CHEBI:136879 5-(carboxymethoxy)uridine 5'-phosphate(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136879 CHEBI:136878 C2-C8-saturated long-chain fatty acyl pantetheine-4-phosphorylserine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136878 CHEBI:136877 5-hydroxyuridine 5'-phosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136877 CHEBI:78415 trioxilin anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78415 GO:0003109 positive regulation of the force of heart contraction by circulating norepinephrine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003109 increased force of heart contraction by circulating norepinephrine|increased force of heart contraction by circulating noradrenaline The process in which the secretion of norepinephrine into the bloodstream modulates the force of heart muscle contraction. GO:1904039 negative regulation of iron export across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904039 down-regulation of iron(2+) export|downregulation of ferrous iron export|negative regulation of ferrous iron export|down-regulation of ferrous iron export|inhibition of iron(2+) export|negative regulation of iron(2+) export|down regulation of iron(2+) export|inhibition of ferrous iron export|downregulation of iron(2+) export|down regulation of ferrous iron export Any process that stops, prevents or reduces the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region. GO:1904038 regulation of iron export across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904038 regulation of iron(2+) export|regulation of ferrous iron export Any process that modulates the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region. GO:1904037 positive regulation of epithelial cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904037 upregulation of epithelial cell apoptotic process|upregulation of epitheliocyte apoptotic process|up regulation of epithelial cell apoptosis|up regulation of epitheliocyte apoptosis|positive regulation of epithelial cell apoptosis|positive regulation of epitheliocyte apoptosis|up regulation of epithelial cell apoptotic process|activation of epithelial cell apoptotic process|up regulation of epitheliocyte apoptotic process|activation of epithelial cell apoptosis|activation of epitheliocyte apoptotic process|activation of epitheliocyte apoptosis|positive regulation of epitheliocyte apoptotic process|up-regulation of epithelial cell apoptosis|up-regulation of epitheliocyte apoptosis|up-regulation of epithelial cell apoptotic process|up-regulation of epitheliocyte apoptotic process|upregulation of epithelial cell apoptosis|upregulation of epitheliocyte apoptosis Any process that activates or increases the frequency, rate or extent of epithelial cell apoptotic process. GO:1904036 negative regulation of epithelial cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904036 down regulation of epitheliocyte apoptosis|downregulation of epithelial cell apoptosis|downregulation of epitheliocyte apoptosis|down regulation of epithelial cell apoptotic process|down regulation of epitheliocyte apoptotic process|downregulation of epithelial cell apoptotic process|downregulation of epitheliocyte apoptotic process|down-regulation of epithelial cell apoptosis|negative regulation of epithelial cell apoptosis|negative regulation of epitheliocyte apoptosis|down-regulation of epitheliocyte apoptosis|down-regulation of epithelial cell apoptotic process|down-regulation of epitheliocyte apoptotic process|negative regulation of epitheliocyte apoptotic process|inhibition of epithelial cell apoptosis|inhibition of epithelial cell apoptotic process|inhibition of epitheliocyte apoptosis|inhibition of epitheliocyte apoptotic process|down regulation of epithelial cell apoptosis Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell apoptotic process. GO:1904046 negative regulation of vascular endothelial growth factor production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904046 down regulation of VEGF production|down regulation of vascular endothelial growth factor production|downregulation of VEGF production|downregulation of vascular endothelial growth factor production|negative regulation of VEGF production|down-regulation of VEGF production|down-regulation of vascular endothelial growth factor production|inhibition of VEGF production|inhibition of vascular endothelial growth factor production Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial growth factor production. GO:1904045 cellular response to aldosterone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904045 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldosterone stimulus. GO:1904044 response to aldosterone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904044 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldosterone stimulus. GO:1904043 positive regulation of cystathionine beta-synthase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904043 up regulation of L-serine hydro-lyase (adding homocysteine)|up regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|up-regulation of beta-thionase activity|upregulation of methylcysteine synthase activity|activation of beta-thionase activity|activation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|positive regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|upregulation of cystathionine beta-synthase activity|up-regulation of serine sulfhydrase activity|up regulation of serine sulfhydrylase activity|activation of serine sulfhydrylase activity|positive regulation of serine sulfhydrylase activity|upregulation of L-serine hydro-lyase (adding homocysteine)|up-regulation of methylcysteine synthase activity|positive regulation of beta-thionase activity|activation of methylcysteine synthase activity|up-regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|up regulation of beta-thionase activity|up-regulation of cystathionine beta-synthase activity|activation of cystathionine beta-synthase activity|upregulation of serine sulfhydrase activity|up-regulation of L-serine hydro-lyase (adding homocysteine)|activation of L-serine hydro-lyase (adding homocysteine)|up-regulation of serine sulfhydrylase activity|positive regulation of methylcysteine synthase activity|upregulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|up regulation of methylcysteine synthase activity|upregulation of beta-thionase activity|up regulation of serine sulfhydrase activity|activation of serine sulfhydrase activity|positive regulation of serine sulfhydrase activity|up regulation of cystathionine beta-synthase activity|upregulation of serine sulfhydrylase activity|positive regulation of L-serine hydro-lyase (adding homocysteine) Any process that activates or increases the frequency, rate or extent of cystathionine beta-synthase activity. GO:1904042 negative regulation of cystathionine beta-synthase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904042 inhibition of methylcysteine synthase activity|down regulation of cystathionine beta-synthase activity|downregulation of L-serine hydro-lyase (adding homocysteine)|downregulation of serine sulfhydrylase activity|inhibition of cystathionine beta-synthase activity|negative regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|inhibition of serine sulfhydrase activity|down-regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|down regulation of L-serine hydro-lyase (adding homocysteine)|negative regulation of beta-thionase activity|down-regulation of beta-thionase activity|inhibition of L-serine hydro-lyase (adding homocysteine)|negative regulation of serine sulfhydrylase activity|down-regulation of serine sulfhydrylase activity|inhibition of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|downregulation of beta-thionase activity|down-regulation of methylcysteine synthase activity|negative regulation of methylcysteine synthase activity|down regulation of serine sulfhydrase activity|inhibition of serine sulfhydrylase activity|down regulation of beta-thionase activity|down-regulation of cystathionine beta-synthase activity|inhibition of beta-thionase activity|downregulation of serine sulfhydrase activity|negative regulation of L-serine hydro-lyase (adding homocysteine)|down-regulation of L-serine hydro-lyase (adding homocysteine)|down regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|downregulation of methylcysteine synthase activity|downregulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|down regulation of methylcysteine synthase activity|downregulation of cystathionine beta-synthase activity|down-regulation of serine sulfhydrase activity|negative regulation of serine sulfhydrase activity|down regulation of serine sulfhydrylase activity Any process that stops, prevents or reduces the frequency, rate or extent of cystathionine beta-synthase activity. GO:0052281 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052281 GO:1904041 regulation of cystathionine beta-synthase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904041 regulation of serine sulfhydrylase activity|regulation of L-serine hydro-lyase (adding homocysteine)|regulation of beta-thionase activity|regulation of serine sulfhydrase activity|regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|regulation of methylcysteine synthase activity Any process that modulates the frequency, rate or extent of cystathionine beta-synthase activity. GO:0052280 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052280 GO:1904040 positive regulation of iron export across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904040 up regulation of iron(2+) export|upregulation of ferrous iron export|activation of iron(2+) export|up regulation of ferrous iron export|positive regulation of ferrous iron export|up-regulation of iron(2+) export|activation of ferrous iron export|positive regulation of iron(2+) export|upregulation of iron(2+) export|up-regulation of ferrous iron export Any process that activates or increases the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region. GO:0052285 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052285 GO:0052284 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052284 GO:0052283 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052283 GO:0052282 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052282 GO:0052289 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052289 GO:0052288 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052288 GO:0052287 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052287 GO:0052286 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052286 GO:1904049 negative regulation of spontaneous neurotransmitter secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904049 down regulation of stimulus-independent neurotransmitter secretion|downregulation of spontaneous neurotransmitter secretion|down regulation of spontaneous neurotransmitter secretion|downregulation of stimulus-independent neurotransmitter secretion|inhibition of spontaneous neurotransmitter secretion|down-regulation of stimulus-independent neurotransmitter secretion|negative regulation of stimulus-independent neurotransmitter secretion|inhibition of stimulus-independent neurotransmitter secretion|down-regulation of spontaneous neurotransmitter secretion Any process that stops, prevents or reduces the frequency, rate or extent of spontaneous neurotransmitter secretion. GO:1904048 regulation of spontaneous neurotransmitter secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904048 regulation of stimulus-independent neurotransmitter secretion Any process that modulates the frequency, rate or extent of spontaneous neurotransmitter secretion. GO:1904047 S-adenosyl-L-methionine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1904047 Reactome:R-HSA-947535 radical SAM enzyme activity Interacting selectively and non-covalently with S-adenosyl-L-methionine. GO:1904057 negative regulation of sensory perception of pain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904057 downregulation of nociception|down-regulation of sensory perception of pain|inhibition of perception of physiological pain|down-regulation of nociception|negative regulation of nociception|downregulation of sensory perception of pain|negative regulation of perception of physiological pain|inhibition of nociception|down-regulation of perception of physiological pain|down regulation of sensory perception of pain|inhibition of sensory perception of pain|downregulation of perception of physiological pain|down regulation of nociception|down regulation of perception of physiological pain Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of pain. GO:1904056 positive regulation of cholangiocyte proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904056 up regulation of hepatoblast proliferation|upregulation of cholangiocyte proliferation|activation of hepatoblast proliferation|positive regulation of hepatoblast proliferation|up regulation of cholangiocyte proliferation|activation of cholangiocyte proliferation|up-regulation of hepatoblast proliferation|upregulation of hepatoblast proliferation|up-regulation of cholangiocyte proliferation Any process that activates or increases the frequency, rate or extent of cholangiocyte proliferation. GO:1904055 negative regulation of cholangiocyte proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904055 downregulation of hepatoblast proliferation|down regulation of cholangiocyte proliferation|down-regulation of hepatoblast proliferation|negative regulation of hepatoblast proliferation|downregulation of cholangiocyte proliferation|inhibition of hepatoblast proliferation|down-regulation of cholangiocyte proliferation|inhibition of cholangiocyte proliferation|down regulation of hepatoblast proliferation Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte proliferation. GO:1904054 regulation of cholangiocyte proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904054 regulation of hepatoblast proliferation Any process that modulates the frequency, rate or extent of cholangiocyte proliferation. GO:1904053 positive regulation of protein targeting to vacuole involved in autophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904053 up-regulation of protein targeting to vacuole involved in autophagy|activation of protein targeting to vacuole involved in autophagy|up regulation of protein targeting to vacuole involved in autophagy|upregulation of protein targeting to vacuole involved in autophagy Any process that activates or increases the frequency, rate or extent of protein targeting to vacuole involved in autophagy. GO:0052292 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052292 GO:1904052 negative regulation of protein targeting to vacuole involved in autophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904052 down-regulation of protein targeting to vacuole involved in autophagy|downregulation of protein targeting to vacuole involved in autophagy|down regulation of protein targeting to vacuole involved in autophagy|inhibition of protein targeting to vacuole involved in autophagy Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to vacuole involved in autophagy. GO:0052291 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052291 GO:1904051 regulation of protein targeting to vacuole involved in autophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904051 Any process that modulates the frequency, rate or extent of protein targeting to vacuole involved in autophagy. GO:0052290 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052290 GO:1904050 positive regulation of spontaneous neurotransmitter secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904050 activation of spontaneous neurotransmitter secretion|up-regulation of spontaneous neurotransmitter secretion|up-regulation of stimulus-independent neurotransmitter secretion|up regulation of spontaneous neurotransmitter secretion|upregulation of stimulus-independent neurotransmitter secretion|up regulation of stimulus-independent neurotransmitter secretion|upregulation of spontaneous neurotransmitter secretion|activation of stimulus-independent neurotransmitter secretion|positive regulation of stimulus-independent neurotransmitter secretion Any process that activates or increases the frequency, rate or extent of spontaneous neurotransmitter secretion. GO:0052296 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052296 GO:0052295 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052295 GO:0052294 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052294 GO:0052293 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052293 GO:0052299 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052299 GO:0052298 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052298 GO:0052297 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052297 GO:1904059 regulation of locomotor rhythm biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904059 regulation of circadian locomotor activity rhythm Any process that modulates the frequency, rate or extent of locomotor rhythm. GO:1904058 positive regulation of sensory perception of pain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904058 activation of sensory perception of pain|upregulation of perception of physiological pain|up regulation of nociception|positive regulation of nociception|activation of nociception|up regulation of sensory perception of pain|up-regulation of perception of physiological pain|activation of perception of physiological pain|up-regulation of nociception|upregulation of sensory perception of pain|positive regulation of perception of physiological pain|up regulation of perception of physiological pain|upregulation of nociception|up-regulation of sensory perception of pain Any process that activates or increases the frequency, rate or extent of sensory perception of pain. GO:1904068 G protein-coupled receptor signaling pathway involved in social behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904068 G protein coupled receptor protein signaling pathway involved in social behaviour|G-protein coupled receptor signalling pathway involved in cooperative behavior|G-protein coupled receptor protein signal transduction involved in social behavior|G protein coupled receptor protein signalling pathway involved in social behaviour|G-protein-coupled receptor protein signaling pathway involved in cooperative behavior|GPCR signalling pathway involved in cooperative behavior|GPCR signalling pathway involved in social behavior|G-protein-coupled receptor protein signaling pathway involved in social behavior|G-protein coupled receptor signaling pathway involved in social behavior|G-protein coupled receptor signalling pathway involved in social behavior|GPCR signaling pathway involved in social behaviour|G-protein coupled receptor protein signal transduction involved in cooperative behavior|G-protein-coupled receptor protein signalling pathway involved in social behaviour|G protein coupled receptor protein signaling pathway involved in cooperative behavior|G protein coupled receptor protein signalling pathway involved in cooperative behavior|G-protein coupled receptor signaling pathway involved in social behaviour|G-protein coupled receptor protein signaling pathway involved in social behaviour|GPCR signaling pathway involved in cooperative behavior|G-protein-coupled receptor protein signalling pathway involved in cooperative behavior|G-protein coupled receptor signaling pathway involved in cooperative behavior|G-protein coupled receptor protein signaling pathway involved in social behavior|G-protein coupled receptor protein signaling pathway involved in cooperative behavior|G-protein-coupled receptor protein signalling pathway involved in social behavior|GPCR signaling pathway involved in social behavior|G-protein coupled receptor signalling pathway involved in social behaviour|G-protein-coupled receptor protein signaling pathway involved in social behaviour|GPCR signalling pathway involved in social behaviour|G protein coupled receptor protein signalling pathway involved in social behavior|G protein coupled receptor protein signaling pathway involved in social behavior|G-protein coupled receptor protein signal transduction involved in social behaviour Any G protein-coupled receptor signaling pathway that is involved in social behavior. GO:1904067 ascr#2 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1904067 Interacting selectively and non-covalently with ascr#2. GO:1904066 G protein-coupled receptor signaling pathway involved in dauer larval development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904066 G-protein coupled receptor signalling pathway involved in dauer larval development|GPCR signalling pathway involved in dauer larval development|G-protein coupled receptor protein signal transduction involved in dauer larval development|G protein coupled receptor protein signaling pathway involved in dauer larval development|G protein coupled receptor protein signalling pathway involved in dauer larval development|GPCR signaling pathway involved in dauer larval development|G-protein-coupled receptor protein signalling pathway involved in dauer larval development|G-protein coupled receptor protein signaling pathway involved in dauer larval development Any G protein-coupled receptor signaling pathway that is involved in dauer larval development. GO:1904065 G protein-coupled acetylcholine receptor signaling pathway involved in positive regulation of acetylcholine secretion, neurotransmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904065 acetylcholine receptor signalling, muscarinic pathway involved in stimulation of acetylcholine secretion|muscarinic acetylcholine receptor signaling pathway involved in activation of acetylcholine secretion|acetylcholine receptor signalling, muscarinic pathway involved in positive regulation of acetylcholine secretion, neurotransmission|G-protein coupled acetylcholine receptor signaling pathway involved in stimulation of acetylcholine secretion|muscarinic acetylcholine receptor signaling pathway involved in up-regulation of acetylcholine secretion|muscarinic acetylcholine receptor signaling pathway involved in positive regulation of acetylcholine secretion, neurotransmission|acetylcholine receptor signalling, muscarinic pathway involved in up-regulation of acetylcholine secretion|G-protein coupled acetylcholine receptor signaling pathway involved in up-regulation of acetylcholine secretion|G-protein coupled acetylcholine receptor signaling pathway involved in upregulation of acetylcholine secretion|G-protein coupled acetylcholine receptor signaling pathway involved in positive regulation of acetylcholine secretion, neurotransmission|acetylcholine receptor signalling, muscarinic pathway involved in upregulation of acetylcholine secretion|muscarinic acetylcholine receptor signaling pathway involved in upregulation of acetylcholine secretion|muscarinic acetylcholine receptor signaling pathway involved in up regulation of acetylcholine secretion|G-protein coupled acetylcholine receptor signaling pathway involved in activation of acetylcholine secretion|acetylcholine receptor signalling, muscarinic pathway involved in up regulation of acetylcholine secretion|muscarinic acetylcholine receptor signaling pathway involved in stimulation of acetylcholine secretion|acetylcholine receptor signalling, muscarinic pathway involved in activation of acetylcholine secretion|G-protein coupled acetylcholine receptor signaling pathway involved in up regulation of acetylcholine secretion Any G protein-coupled acetylcholine receptor signaling pathway that is involved in positive regulation of acetylcholine secretion, neurotransmission. GO:1904064 positive regulation of cation transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904064 up regulation of cation transmembrane transport|upregulation of cation transmembrane transport|activation of cation transmembrane transport|up-regulation of cation transmembrane transport Any process that activates or increases the frequency, rate or extent of cation transmembrane transport. GO:1904063 negative regulation of cation transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904063 down-regulation of cation transmembrane transport|downregulation of cation transmembrane transport|down regulation of cation transmembrane transport|inhibition of cation transmembrane transport Any process that stops, prevents or reduces the frequency, rate or extent of cation transmembrane transport. GO:1904062 regulation of cation transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904062 Any process that modulates the frequency, rate or extent of cation transmembrane transport. GO:1904061 positive regulation of locomotor rhythm biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904061 activation of locomotor rhythm|positive regulation of circadian locomotor activity rhythm|activation of circadian locomotor activity rhythm|up-regulation of circadian locomotor activity rhythm|up regulation of locomotor rhythm|upregulation of circadian locomotor activity rhythm|upregulation of locomotor rhythm|up regulation of circadian locomotor activity rhythm|up-regulation of locomotor rhythm Any process that activates or increases the frequency, rate or extent of locomotor rhythm. GO:1904060 negative regulation of locomotor rhythm biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904060 negative regulation of circadian locomotor activity rhythm|down-regulation of circadian locomotor activity rhythm|down-regulation of locomotor rhythm|inhibition of circadian locomotor activity rhythm|downregulation of locomotor rhythm|down regulation of locomotor rhythm|inhibition of locomotor rhythm|down regulation of circadian locomotor activity rhythm|downregulation of circadian locomotor activity rhythm Any process that stops, prevents or reduces the frequency, rate or extent of locomotor rhythm. GO:1904069 ascaroside metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904069 ascaroside metabolism The chemical reactions and pathways involving ascaroside. GO:1904079 obsolete negative regulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904079 inhibition of transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|downregulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|downregulation of transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|downregulation of global transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|inhibition of global transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|negative regulation of global transcription from Pol II promoter involved in down regulation of neuron apoptosis|inhibition of transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter, global involved in downregulation of neuron apoptosis|down regulation of transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons|inhibition of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|down regulation of global transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons|inhibition of global transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|inhibition of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|negative regulation of transcription from Pol II promoter involved in neuron survival|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter, global involved in down regulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|down-regulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|negative regulation of global transcription from Pol II promoter involved in downregulation of neuron apoptosis|negative regulation of transcription from Pol II promoter involved in inhibition of neuron apoptosis|downregulation of global transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|down-regulation of transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|down-regulation of global transcription from RNA polymerase II promoter involved in neuron survival|downregulation of transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons|down regulation of global transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|inhibition of transcription from RNA polymerase II promoter involved in neuron survival|down regulation of global transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|down-regulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|down-regulation of transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|down regulation of transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|inhibition of global transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons|down-regulation of global transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons|negative regulation of transcription from Pol II promoter involved in negative regulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|negative regulation of global transcription from Pol II promoter involved in neuron survival|down-regulation of transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|downregulation of global transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter, global involved in inhibition of neuron apoptosis|downregulation of transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|downregulation of transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter, global involved in neuron survival|down-regulation of global transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|down-regulation of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|down regulation of transcription from RNA polymerase II promoter involved in neuron survival|down-regulation of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|negative regulation of transcription from Pol II promoter involved in down-regulation of neuron apoptosis|inhibition of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|down-regulation of transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons|downregulation of global transcription from RNA polymerase II promoter involved in neuron survival|negative regulation of transcription from Pol II promoter involved in negative regulation of neuron apoptotic process|negative regulation of global transcription from Pol II promoter involved in inhibition of neuron apoptosis|inhibition of global transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|down regulation of transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|downregulation of transcription from RNA polymerase II promoter involved in neuron survival|down regulation of global transcription from RNA polymerase II promoter involved in neuron survival|negative regulation of global transcription from Pol II promoter involved in negative regulation of neuron apoptosis|negative regulation of global transcription from Pol II promoter involved in negative regulation of neuron apoptotic process|negative regulation of global transcription from Pol II promoter involved in down-regulation of neuron apoptosis|down-regulation of global transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|downregulation of transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|inhibition of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|inhibition of transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|down-regulation of global transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons|negative regulation of transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|inhibition of global transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|down-regulation of transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|negative regulation of transcription from Pol II promoter involved in negative regulation of programmed cell death, neurons|negative regulation of transcription from RNA polymerase II promoter, global involved in down-regulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter, global involved in negative regulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter, global involved in negative regulation of neuron apoptotic process|down regulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|downregulation of global transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|downregulation of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|downregulation of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|down regulation of transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|inhibition of transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|inhibition of global transcription from RNA polymerase II promoter involved in neuron survival|downregulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|negative regulation of global transcription from Pol II promoter involved in negative regulation of programmed cell death, neurons|down regulation of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|down regulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|down-regulation of global transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter involved in neuron survival|down-regulation of transcription from RNA polymerase II promoter involved in neuron survival|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in neuron survival|down regulation of global transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|inhibition of transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons|down regulation of transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|down regulation of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|down regulation of global transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|negative regulation of transcription from Pol II promoter involved in down regulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter, global involved in negative regulation of programmed cell death, neurons|negative regulation of transcription from Pol II promoter involved in downregulation of neuron apoptosis|downregulation of global transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons OBSOLETE. Any negative regulation of transcription from RNA polymerase II promoter that is involved in negative regulation of neuron apoptotic process. GO:1904078 positive regulation of estrogen biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904078 positive regulation of estrogen biosynthesis|activation of estrogen synthesis|activation of estrogen biosynthesis|activation of estrogen biosynthetic process|up-regulation of estrogen formation|activation of estrogen formation|positive regulation of estrogen anabolism|upregulation of oestrogen biosynthesis|upregulation of oestrogen biosynthetic process|up regulation of estrogen anabolism|positive regulation of estrogen synthesis|up-regulation of estrogen biosynthetic process|up-regulation of estrogen biosynthesis|up regulation of estrogen synthesis|positive regulation of estrogen formation|up regulation of estrogen formation|up-regulation of oestrogen biosynthesis|up-regulation of oestrogen biosynthetic process|activation of oestrogen biosynthesis|activation of oestrogen biosynthetic process|upregulation of estrogen anabolism|upregulation of estrogen biosynthesis|upregulation of estrogen biosynthetic process|upregulation of estrogen synthesis|upregulation of estrogen formation|up-regulation of estrogen anabolism|positive regulation of oestrogen biosynthetic process|positive regulation of oestrogen biosynthesis|activation of estrogen anabolism|up regulation of oestrogen biosynthesis|up regulation of oestrogen biosynthetic process|up regulation of estrogen biosynthesis|up regulation of estrogen biosynthetic process|up-regulation of estrogen synthesis Any process that activates or increases the frequency, rate or extent of estrogen biosynthetic process. GO:1904077 negative regulation of estrogen biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904077 downregulation of oestrogen biosynthesis|downregulation of oestrogen biosynthetic process|negative regulation of estrogen anabolism|down-regulation of estrogen anabolism|down-regulation of estrogen biosynthetic process|negative regulation of estrogen biosynthesis|down regulation of oestrogen biosynthesis|down-regulation of estrogen biosynthesis|down regulation of oestrogen biosynthetic process|inhibition of oestrogen biosynthetic process|negative regulation of estrogen synthesis|down-regulation of estrogen synthesis|inhibition of oestrogen biosynthesis|negative regulation of estrogen formation|down-regulation of estrogen formation|downregulation of estrogen anabolism|inhibition of estrogen biosynthesis|inhibition of estrogen biosynthetic process|downregulation of estrogen synthesis|down regulation of estrogen anabolism|inhibition of estrogen anabolism|downregulation of estrogen formation|down regulation of estrogen synthesis|inhibition of estrogen synthesis|down regulation of estrogen formation|down-regulation of oestrogen biosynthesis|negative regulation of oestrogen biosynthetic process|down regulation of estrogen biosynthesis|negative regulation of oestrogen biosynthesis|down-regulation of oestrogen biosynthetic process|down regulation of estrogen biosynthetic process|inhibition of estrogen formation|downregulation of estrogen biosynthetic process|downregulation of estrogen biosynthesis Any process that stops, prevents or reduces the frequency, rate or extent of estrogen biosynthetic process. GO:1904076 regulation of estrogen biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904076 regulation of oestrogen biosynthesis|regulation of oestrogen biosynthetic process|regulation of estrogen anabolism|regulation of estrogen synthesis|regulation of estrogen formation|regulation of estrogen biosynthesis Any process that modulates the frequency, rate or extent of estrogen biosynthetic process. GO:1904075 positive regulation of trophectodermal cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904075 upregulation of trophectoderm cell proliferation|up regulation of trophectodermal cell proliferation|up-regulation of trophectoderm cell proliferation|activation of trophectoderm cell proliferation|upregulation of trophectodermal cell proliferation|positive regulation of trophectoderm cell proliferation|up-regulation of trophectodermal cell proliferation|activation of trophectodermal cell proliferation|up regulation of trophectoderm cell proliferation Any process that activates or increases the frequency, rate or extent of trophectodermal cell proliferation. GO:1904074 negative regulation of trophectodermal cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904074 down-regulation of trophectodermal cell proliferation|down regulation of trophectoderm cell proliferation|inhibition of trophectoderm cell proliferation|downregulation of trophectodermal cell proliferation|down regulation of trophectodermal cell proliferation|inhibition of trophectodermal cell proliferation|down-regulation of trophectoderm cell proliferation|negative regulation of trophectoderm cell proliferation|downregulation of trophectoderm cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of trophectodermal cell proliferation. GO:1904073 regulation of trophectodermal cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904073 regulation of trophectoderm cell proliferation Any process that modulates the frequency, rate or extent of trophectodermal cell proliferation. GO:1904072 presynaptic active zone disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904072 pre-synaptic active zone component disassembly|pre-synaptic active zone disassembly The disaggregation of a presynaptic active zone into its constituent components. GO:1904071 presynaptic active zone assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904071 pre-synaptic active zone assembly|pre-synaptic active zone component formation|pre-synaptic active zone formation|presynaptic active zone formation|pre-synaptic active zone component assembly The aggregation, arrangement and bonding together of a set of components to form a presynaptic active zone. The presynaptic active zone is a specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, and a specialized cortical cytoskeletal matrix. GO:1904070 ascaroside biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904070 ascaroside anabolism|ascaroside synthesis|ascaroside formation|ascaroside biosynthesis The chemical reactions and pathways resulting in the formation of ascaroside. GO:1904089 negative regulation of neuron apoptotic process by negative regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904089 negative regulation of neuron apoptosis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of programmed cell death, neurons by negative regulation of transcription from RNA polymerase II promoter A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of neuron apoptotic process. GO:1904088 positive regulation of epiboly involved in gastrulation with mouth forming second biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904088 up regulation of epiboly involved in gastrulation with mouth forming second|upregulation of epiboly involved in gastrulation with mouth forming second|up-regulation of epiboly involved in gastrulation with mouth forming second|activation of epiboly involved in gastrulation with mouth forming second Any process that activates or increases the frequency, rate or extent of epiboly involved in gastrulation with mouth forming second. GO:1904087 negative regulation of epiboly involved in gastrulation with mouth forming second biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904087 downregulation of epiboly involved in gastrulation with mouth forming second|down regulation of epiboly involved in gastrulation with mouth forming second|inhibition of epiboly involved in gastrulation with mouth forming second|down-regulation of epiboly involved in gastrulation with mouth forming second Any process that stops, prevents or reduces the frequency, rate or extent of epiboly involved in gastrulation with mouth forming second. GO:1904086 regulation of epiboly involved in gastrulation with mouth forming second biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904086 Any process that modulates the frequency, rate or extent of epiboly involved in gastrulation with mouth forming second. GO:1904085 obsolete positive regulation of epiboly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904085 positive regulation of epiboly|upregulation of epiboly|up regulation of epiboly|activation of epiboly|up-regulation of epiboly OBSOLETE. Any process that activates or increases the frequency, rate or extent of epiboly. GO:1904084 obsolete negative regulation of epiboly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904084 negative regulation of epiboly|down regulation of epiboly|downregulation of epiboly|down-regulation of epiboly|inhibition of epiboly OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of epiboly. GO:1904083 obsolete regulation of epiboly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904083 regulation of epiboly OBSOLETE. Any process that modulates the frequency, rate or extent of epiboly. GO:1904082 pyrimidine nucleobase transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904082 The process in which pyrimidine is transported across a membrane. GO:1904081 positive regulation of transcription from RNA polymerase II promoter involved in neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904081 upregulation of transcription from RNA polymerase II promoter involved in neuron differentiation|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in neuron differentiation|upregulation of global transcription from RNA polymerase II promoter involved in neuron differentiation|positive regulation of transcription from Pol II promoter involved in neuron differentiation|up-regulation of transcription from RNA polymerase II promoter involved in neuron differentiation|stimulation of transcription from RNA polymerase II promoter involved in neuron differentiation|stimulation of global transcription from RNA polymerase II promoter involved in neuron differentiation|up regulation of global transcription from RNA polymerase II promoter involved in neuron differentiation|activation of transcription from RNA polymerase II promoter involved in neuron differentiation|positive regulation of transcription from RNA polymerase II promoter, global involved in neuron differentiation|positive regulation of global transcription from Pol II promoter involved in neuron differentiation|activation of global transcription from RNA polymerase II promoter involved in neuron differentiation|up regulation of transcription from RNA polymerase II promoter involved in neuron differentiation|up-regulation of global transcription from RNA polymerase II promoter involved in neuron differentiation Any positive regulation of transcription from RNA polymerase II promoter that is involved in neuron differentiation. GO:1904080 obsolete positive regulation of transcription from RNA polymerase II promoter involved in neuron fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904080 up-regulation of transcription from RNA polymerase II promoter involved in neuron fate specification|positive regulation of global transcription from Pol II promoter involved in neuron fate specification|positive regulation of transcription from RNA polymerase II promoter, global involved in neuron fate specification|positive regulation of transcription from Pol II promoter involved in neuron fate specification|up regulation of global transcription from RNA polymerase II promoter involved in neuron fate specification|upregulation of transcription from RNA polymerase II promoter involved in neuron fate specification|upregulation of global transcription from RNA polymerase II promoter involved in neuron fate specification|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in neuron fate specification|stimulation of global transcription from RNA polymerase II promoter involved in neuron fate specification|up regulation of transcription from RNA polymerase II promoter involved in neuron fate specification|up-regulation of global transcription from RNA polymerase II promoter involved in neuron fate specification|activation of transcription from RNA polymerase II promoter involved in neuron fate specification|stimulation of transcription from RNA polymerase II promoter involved in neuron fate specification|activation of global transcription from RNA polymerase II promoter involved in neuron fate specification OBSOLETE. Any positive regulation of transcription from RNA polymerase II promoter that is involved in neuron fate specification. CHEBI:136485 8(S),15(S)-DiHETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136485 GO:1904099 negative regulation of protein O-linked glycosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904099 down-regulation of protein O-linked glycosylation|down regulation of protein amino acid O-linked glycosylation|downregulation of protein O-linked glycosylation|downregulation of protein amino acid O-linked glycosylation|down regulation of protein O-linked glycosylation|inhibition of protein O-linked glycosylation|negative regulation of protein amino acid O-linked glycosylation|down-regulation of protein amino acid O-linked glycosylation|inhibition of protein amino acid O-linked glycosylation Any process that stops, prevents or reduces the frequency, rate or extent of protein O-linked glycosylation. GO:1904098 regulation of protein O-linked glycosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904098 regulation of protein amino acid O-linked glycosylation Any process that modulates the frequency, rate or extent of protein O-linked glycosylation. GO:1904097 acid phosphatase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1904097 A protein complex which is capable of acid phosphatase activity. GO:1904096 protein tyrosine phosphatase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1904096 A protein complex which is capable of protein tyrosine phosphatase activity. GO:1904095 negative regulation of endosperm development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904095 down regulation of endosperm development|downregulation of endosperm development|down-regulation of endosperm development|inhibition of endosperm development Any process that stops, prevents or reduces the frequency, rate or extent of endosperm development. GO:1904094 positive regulation of autophagic cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904094 up regulation of programmed cell death by macroautophagy|activation of programmed cell death by macroautophagy|positive regulation of programmed cell death by macroautophagy|up regulation of autophagic cell death|up regulation of type II programmed cell death|activation of autophagic cell death|positive regulation of type II programmed cell death|up-regulation of programmed cell death by macroautophagy|activation of type II programmed cell death|up-regulation of type II programmed cell death|up-regulation of autophagic cell death|upregulation of programmed cell death by macroautophagy|upregulation of autophagic cell death|upregulation of type II programmed cell death Any process that activates or increases the frequency, rate or extent of autophagic cell death. GO:1904093 negative regulation of autophagic cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904093 down regulation of type II programmed cell death|down regulation of autophagic cell death|downregulation of autophagic cell death|downregulation of type II programmed cell death|down-regulation of programmed cell death by macroautophagy|negative regulation of programmed cell death by macroautophagy|inhibition of programmed cell death by macroautophagy|down-regulation of autophagic cell death|down-regulation of type II programmed cell death|negative regulation of type II programmed cell death|inhibition of autophagic cell death|down regulation of programmed cell death by macroautophagy|inhibition of type II programmed cell death|downregulation of programmed cell death by macroautophagy Any process that stops, prevents or reduces the frequency, rate or extent of autophagic cell death. CHEBI:136494 N-(2-ethyl-6-methylphenyl)-2-chloroacetamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136494 GO:1904092 regulation of autophagic cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904092 regulation of programmed cell death by autophagy|regulation of type II programmed cell death|regulation of programmed cell death by macroautophagy|regulation of autophagic death Any process that modulates the frequency, rate or extent of autophagic cell death. CHEBI:136493 phosphatidylinositol (16:0/18:2) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136493 GO:1904091 peptidyl carrier protein activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1904091 oligopeptido binding involved in nonribosomal peptide formation|oligopeptide binding involved in non-ribosomal peptide synthesis|Oligopeptid binding involved in nonribosomal peptide formation|peptidyl carrier protein|peptidyl carrier protein activity involved in nonribosomal peptide biosynthetic process|oligopeptides binding involved in nonribosomal peptide anabolism|oligopeptide binding involved in non-ribosomal peptide formation|peptidyl binding involved in nonribosomal peptide biosynthetic process|peptidyl binding involved in nonribosomal peptide biosynthesis|oligopeptides binding involved in nonribosomal peptide synthesis|Oligopeptid binding involved in nonribosomal peptide biosynthesis|Oligopeptid binding involved in nonribosomal peptide biosynthetic process|oligopeptides binding involved in non-ribosomal peptide synthesis|oligopeptido binding involved in nonribosomal peptide biosynthetic process|oligopeptido binding involved in nonribosomal peptide biosynthesis|oligopeptido binding involved in non-ribosomal peptide biosynthetic process|oligopeptide binding involved in nonribosomal peptide anabolism|oligopeptido binding involved in non-ribosomal peptide biosynthesis|oligopeptides binding involved in nonribosomal peptide formation|Oligopeptid binding involved in non-ribosomal peptide biosynthesis|Oligopeptid binding involved in non-ribosomal peptide biosynthetic process|oligopeptides binding involved in non-ribosomal peptide formation|Oligopeptid binding involved in nonribosomal peptide synthetase|oligopeptido binding involved in nonribosomal peptide synthetase|oligopeptide binding involved in nonribosomal peptide synthesis|oligopeptide binding involved in nonribosomal peptide biosynthetic process|oligopeptide binding involved in nonribosomal peptide biosynthesis|oligopeptide binding involved in nonribosomal peptide formation|oligopeptides binding involved in non-ribosomal peptide biosynthetic process|oligopeptides binding involved in non-ribosomal peptide biosynthesis|peptidyl carrier protein activity involved in nonribosomal peptide biosynthesis|oligopeptides binding involved in nonribosomal peptide biosynthesis|oligopeptides binding involved in nonribosomal peptide biosynthetic process|oligopeptide binding involved in nonribosomal peptide synthetase|PCP|oligopeptido binding involved in nonribosomal peptide anabolism|Oligopeptid binding involved in nonribosomal peptide anabolism|oligopeptide binding involved in non-ribosomal peptide biosynthesis|oligopeptide binding involved in non-ribosomal peptide biosynthetic process|Oligopeptid binding involved in non-ribosomal peptide synthesis|oligopeptido binding involved in non-ribosomal peptide synthesis|oligopeptido binding involved in nonribosomal peptide synthesis|Oligopeptid binding involved in nonribosomal peptide synthesis|oligopeptides binding involved in nonribosomal peptide synthetase|Oligopeptid binding involved in non-ribosomal peptide formation|oligopeptido binding involved in non-ribosomal peptide formation Binding an amino-acid derived peptidyl group and presenting it for processing or offloading to a cognate enzyme. Covalently binds the peptidyl group via a phosphopantetheine prosthetic group and mediates protein-protein interactions with the enzyme conferring specificity. Peptidyl carrier protein (PCP) is involved in nonribosomal peptide biosynthetic process. CHEBI:136492 N-(2,6-diethylphenyl)-2-chloroacetamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136492 GO:1904090 peptidase inhibitor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1904090 Cathepsin-B - cystatin-A complex A protein complex which is capable of peptidase inhibitor activity. GO:0003299 muscle hypertrophy in response to stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003299 The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells as a result of a disturbance in organismal or cellular homeostasis. GO:0003296 apoptotic process involved in atrial ventricular junction remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003296 apoptosis involved in atrial ventricular junction remodeling|apoptosis involved in atrioventricular junction remodeling|apoptosis involved in atrio-ventricular junction remodeling Any apoptotic process that contributes to the reorganization of tissue resulting in the maturation of the atrial ventricular junction. GO:0003295 cell proliferation involved in atrial ventricular junction remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003295 cell proliferation involved in atrioventricular junction remodeling|cell proliferation involved in atrio-ventricular junction remodeling The multiplication or reproduction of cells that contributes to the reorganization of tissue resulting in the maturation of the atrial ventricular junction. GO:0003298 physiological muscle hypertrophy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003298 The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development. GO:0003297 heart wedging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003297 The morphogenetic process in which the aorta inserts between the atrioventricular valves, contributing to the shaping of the heart. GO:0003292 cardiac septum cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003292 The process in which an endocardial cushion cell becomes a cell of a cardiac septum. GO:0003291 atrial septum intermedium morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003291 The process in which anatomical structure of an atrial septum intermedium is generated and organized. GO:0003294 atrial ventricular junction remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003294 atrioventricular junction remodeling|atrio-ventricular junction remodeling The reorganization or renovation of heart tissue that contributes to the maturation of the connection between an atrium and a ventricle. GO:0003293 heart valve cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003293 The process in which an endocardial cushion cell give rise to a cell that is part of a heart valve. CL:1000549 kidney cortex collecting duct epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000549 CL:1000548 kidney outer medulla collecting duct epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000548 CL:1000547 kidney inner medulla collecting duct epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000547 CHEBI:136471 phosphatidylethanolamine (16:1/16:1) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136471 GO:0052205 modulation of molecular function in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052205 modification of molecular function in other organism during symbiotic interaction|modification of protein function in other organism during symbiotic interaction|modulation of molecular function in other organism during symbiotic interaction The process in which an organism effects a change in the function of proteins in a second organism, where the two organisms are in a symbiotic interaction. CHEBI:30408 iron-sulfur cluster biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30408 GO:0052204 negative regulation of molecular function in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052204 down regulation of protein function in other organism during symbiotic interaction|inhibition of protein function in other organism|negative regulation of protein function in other organism during symbiotic interaction|downregulation of protein function in other organism during symbiotic interaction|down-regulation of protein function in other organism during symbiotic interaction|inhibition of protein function in other organism during symbiotic interaction Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the functional activity of proteins in a second organism, where the two organisms are in a symbiotic interaction. CHEBI:30407 4-phospho-L-aspartate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30407 GO:0052203 modulation of catalytic activity in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052203 modulation of enzyme activity within other organism during symbiotic interaction The process in which an organism effects a change in enzyme activity in a second organism, where the two organisms are in a symbiotic interaction. GO:0052202 obsolete negative regulation by symbiont of defense-related host cell wall callose deposition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052202 inhibition by symbiont of defense-related host cell wall callose deposition|down regulation by symbiont of defense-related host cell wall callose deposition|negative regulation by organism of defense-related callose deposition in other organism involved in symbiotic interaction|downregulation by symbiont of defense-related host cell wall callose deposition|negative regulation by organism of defense-related cell wall callose deposition in other organism involved in symbiotic interaction|down-regulation by symbiont of defense-related host cell wall callose deposition|negative regulation by symbiont of defense-related host callose deposition OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the deposition of callose by the host in its cell walls, occurring as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052209 obsolete interaction with other organism via substance secreted by type IV secretion system involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052209 interaction with other organism via substance secreted by type IV secretion system during symbiotic interaction OBSOLETE. An interaction with a second organism mediated by a substance secreted by the first organism by a type IV secretion system, where the two organisms are in a symbiotic interaction. GO:0052208 obsolete modification of morphology or physiology of other organism via substance secreted by type IV secretion system involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052208 modification of morphology or physiology of other organism via substance secreted by type IV secretion system during symbiotic interaction OBSOLETE. The process in which an organism effects a change in the structure or function of a second organism, mediated by a substance secreted by a type IV secretion system in the first organism, where the two organisms are in a symbiotic interaction. GO:0052207 obsolete modification of morphology or physiology of other organism via protein secreted by type III secretion system involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052207 modification of morphology or physiology of other organism via protein secreted by type III secretion system during symbiotic interaction OBSOLETE. The process in which an organism effects a change in the structure or function of a second organism, mediated by a substance secreted by a type III secretion system in the first organism, where the two organisms are in a symbiotic interaction. GO:0052206 obsolete modification of morphology or physiology of other organism via protein secreted by type II secretion system involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052206 modification of morphology or physiology of other organism via protein secreted by type II secretion system during symbiotic interaction OBSOLETE. The process in which an organism effects a change in the structure or function of a second organism, mediated by a substance secreted by a type II secretion system in the first organism, where the two organisms are in a symbiotic interaction. GO:0042882 L-arabinose transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042882 L-arabinose transport The process in which L-arabinose, the L-enantiomer of arabinose, is transported across a lipid bilayer, from one side of a membrane to the other. GO:0042881 D-galactonate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042881 Enables the transfer of D-galactonate, the D-enantiomer of galactonate, from one side of a membrane to the other. GO:0042884 microcin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042884 The directed movement of microcin, a class of glycine-rich, bactericidal peptides (antibiotics) produced by some enteric bacteria, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0042883 cysteine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042883 L-cysteine transport The directed movement of cysteine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:29412 oxonium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29412 GO:0042880 D-glucuronate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042880 Enables the transfer of D-glucuronate, the D-enantiomer of glucuronate, from one side of a membrane to the other. CHEBI:30409 iron-sulfur-molybdenum cofactor biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30409 GO:0042889 3-phenylpropionic acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042889 HCA transport|hydrocinnamic acid transport|3-phenylpropionate transport The directed movement of 3-phenylpropionic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0042886 amide transport biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0042886 The directed movement of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:78385 1-palmityl-2-acetyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78385 GO:0042885 microcin B17 transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042885 The directed movement of microcin B17, a bactericidal peptide (antibiotic) produced by some enteric bacteria, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0042888 molybdenum ion transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042888 Enables the transfer of molybdenum (Mo) ions from one side of a membrane to the other. GO:0042887 amide transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042887 amine/amide/polyamine channel activity Enables the transfer of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, from one side of a membrane to the other. CHEBI:78387 1-hexadecyl-2-acetyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78387 GO:0052201 response to symbiont defenses biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052201 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the defenses of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052200 response to host defenses biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052200 response to host defense molecules|response of symbiont to host defense molecules|maintenance of symbiont tolerance to host defense molecules Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the defenses of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052216 obsolete chemotaxis in environment of other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052216 chemotaxis in environment of other organism during symbiotic interaction|chemotaxis in response to environment of other organism OBSOLETE. The directed movement of a motile cell or organism in response to a specific chemical concentration gradient on, within or near a second organism, where the two organisms are in a symbiotic interaction. GO:0052215 obsolete energy taxis in environment of other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052215 energy taxis in response to environment of other organism|energy taxis in environment of other organism during symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism in the environment of a second organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction. GO:0052214 metabolism of substance in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052214 metabolism of substance in other organism during symbiotic interaction The chemical reactions and pathways performed by an organism in a second organism, where the two organisms are in a symbiotic interaction. GO:0052213 obsolete interaction with symbiont via secreted substance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052213 interaction with symbiont via secreted substance involved in symbiotic interaction|interaction with symbiont via secreted substance during symbiotic interaction OBSOLETE. An interaction with a symbiont organism mediated by a substance secreted by a host organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052219 obsolete negative energy taxis in environment of other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052219 negative energy taxis in environment of other organism during symbiotic interaction|negative energy taxis in response to environment of other organism OBSOLETE. The directed movement of a motile cell or organism on, within or near a second organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction. GO:0052218 obsolete positive energy taxis in environment of other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052218 positive energy taxis in environment of other organism during symbiotic interaction|positive energy taxis in response to environment of other organism OBSOLETE. The directed movement of a motile cell or organism on, within or near a second organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction. CHEBI:30413 heme biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30413 GO:0052217 obsolete aerotaxis in environment of other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052217 aerotaxis in environment of other organism during symbiotic interaction|aerotaxis in response to environment of other organism OBSOLETE. The movement of a motile cell or organism in response to environmental oxygen on, within or near a second organism, where the two organisms are in a symbiotic interaction. CHEBI:30412 monoatomic dication biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30412 GO:0042893 polymyxin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042893 The directed movement of polymyxin, any of a group of related antibiotics produced by Bacillus polymyxa and active against most Gram-negative bacteria, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0042892 chloramphenicol transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042892 chloramphenicol transport The directed movement of chloramphenicol, a broad-spectrum antibiotic that inhibits bacterial protein synthesis, across a lipid bilayer, from one side of a membrane to the other. GO:0042895 obsolete antibiotic transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042895 antibiotic transporter activity OBSOLETE. Enables the transfer of an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms, from one side of a membrane to the other. GO:0042894 fosmidomycin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042894 The directed movement of fosmidomycin, a phosphonic acid derivative with potent activity against Gram-negative organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0042891 obsolete antibiotic transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042891 OBSOLETE. The directed movement of an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0042890 3-phenylpropionic acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042890 hydrocinnamic acid transporter activity|3-phenylpropionate acid transporter activity|HCA transporter activity Enables the transfer of 3-phenylpropionic acid from one side of a membrane to the other. UBERON:0007245 nuclear complex of neuraxis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007245 nuclear complex|neural nuclei|cluster of neural nuclei Gray matter of the central nervous system which is a collection of clustered nuclei. UBERON:0007244 inferior olivary nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007244 inferior olive The inferior olivary nucleus is the largest nucleus situated in the olivary body, part of the medulla oblongata. CHEBI:78390 1-hexadecyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78390 UBERON:0007243 tunica media of vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007243 venous media|tunica media (venae) A tunica media that is part of a vein. GO:0042897 polymyxin transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042897 polymyxin transporter activity Enables the transfer of polymyxin, any of a group of related antibiotics produced by Bacillus polymyxa and active against most Gram-negative bacteria, from one side of a membrane to the other. UBERON:0007242 tunica intima of vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007242 tunica interna (intima)(venae)|venous intima A tunica intima that is part of a vein. CHEBI:78396 4-hydroxy-3-polyprenylbenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78396 UBERON:0007241 tunica adventitia of vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007241 tunica externa (adventitia)(venae)|venous adventitia A tunica adventitia that is part of a vein. GO:0042896 chloramphenicol transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042896 chloramphenicol transporter activity Enables the transfer of chloramphenicol, a broad-spectrum antibiotic that inhibits bacterial protein synthesis, from one side of a membrane to the other. GO:0042899 arabinan transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042899 arabinan transport The process in which arabinan is transported across a lipid bilayer, from one side of a membrane to the other. UBERON:0007240 tunica adventitia of artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007240 arterial adventitia|tunica externa (adventitia)(arteriae) A tunica adventitia that is part of a artery. GO:0042898 fosmidomycin transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042898 fosmidomycin transporter activity Enables the transfer of fosmidomycin, a phosphonic acid derivative with potent activity against Gram-negative organisms, from one side of a membrane to the other. CHEBI:30411 cobalamin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30411 GO:0052212 obsolete modification of morphology or physiology of other organism via secreted substance involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052212 modification of morphology or physiology of other organism via secreted substance during symbiotic interaction|modification of host morphology or physiology via effector molecule|modification of host morphology or physiology via ellicitor OBSOLETE. The process in which an organism effects a change in the structure or function of a second organism, mediated by a substance secreted by one of the organisms, where the two organisms are in a symbiotic interaction. GO:0052211 obsolete interaction with other organism via protein secreted by type II secretion system involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052211 interaction with other organism via protein secreted by type II secretion system during symbiotic interaction OBSOLETE. An interaction with a second organism mediated by a substance secreted by the first organism by a type II secretion system, where the two organisms are in a symbiotic interaction. GO:0052210 obsolete interaction with other organism via protein secreted by type III secretion system involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052210 interaction with other organism via protein secreted by type III secretion system during symbiotic interaction OBSOLETE. An interaction with a second organism mediated by a substance secreted by the first organism by a type III secretion system, where the two organisms are in a symbiotic interaction. UBERON:0007247 nucleus of superior olivary complex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007247 superior olivary complex nucleus Any of the nuclei that comprise the superior olivary complex (superior olive). This includes both the primary nuclei such as the lateral and medial nuclei, as well as periolivary nuclei. GO:0052227 catabolism of substance in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052227 catabolism of substance in other organism during symbiotic interaction The chemical reactions and pathways performed by an organism in a second organism resulting in the breakdown of substances, where the two organisms are in a symbiotic interaction. GO:0052226 obsolete biosynthesis of substance in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052226 biosynthesis of substance in other organism during symbiotic interaction OBSOLETE. The chemical reactions and pathways performed by an organism in a second organism resulting in the formation of substances, where the two organisms are in a symbiotic interaction. GO:0052225 obsolete energy taxis on or near other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052225 energy taxis on or near other organism during symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism on or near a second organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction. GO:0052224 obsolete energy taxis in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052224 energy taxis within other organism during symbiotic interaction|energy taxis in other organism during symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism within a second organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction. GO:0052229 metabolism of macromolecule in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052229 metabolism of macromolecule in other organism during symbiotic interaction The chemical reactions and pathways performed by an organism involving macromolecules within a second organism, where the two organisms are in a symbiotic interaction. GO:0052228 metabolism by symbiont of host protein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052228 The chemical reactions and pathways performed by an organism involving protein macromolecules within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. CL:1000510 kidney glomerular epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000510 GO:0052223 obsolete negative chemotaxis in environment of other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052223 negative chemotaxis in response to environment of other organism|negative chemotaxis in environment of other organism during symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of a specific chemical on, within or near a second organism, where the two organisms are in a symbiotic interaction. UBERON:0007239 tunica media of artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007239 arterial media|tunica media (arteriae) A tunica media that is part of a artery. GO:0052222 obsolete negative aerotaxis in environment of other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052222 negative aerotaxis in response to environment of other organism|negative aerotaxis in environment of other organism during symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen on, within or near a second organism, where the two organisms are in a symbiotic interaction. UBERON:0007238 1st arch maxillary component biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007238 GO:0052221 obsolete positive chemotaxis in environment of other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052221 positive chemotaxis in environment of other organism during symbiotic interaction|positive chemotaxis in response to environment of other organism OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of a chemical on, within or near a second organism, where the two organisms are in a symbiotic interaction. UBERON:0007237 1st arch mandibular component biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007237 ventral visceral arch 1|ventral mandibular arch|ventral pharyngeal arch 1 GO:0052220 obsolete positive aerotaxis in environment of other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052220 positive aerotaxis in response to environment of other organism|positive aerotaxis in environment of other organism during symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen on, within or near a second organism, where the two organisms are in a symbiotic interaction. GO:0052238 obsolete aerotaxis on or near other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052238 aerotaxis on or near other organism during symbiotic interaction OBSOLETE. The movement of a motile cell or organism in response to environmental oxygen on or near a second organism, where the two organisms are in a symbiotic interaction. GO:0052237 obsolete aerotaxis in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052237 aerotaxis in other organism during symbiotic interaction|aerotaxis within other organism during symbiotic interaction OBSOLETE. The movement of a motile cell or organism in response to environmental oxygen within a second organism, where the two organisms are in a symbiotic interaction. GO:0052236 obsolete negative chemotaxis on or near other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052236 negative chemotaxis on or near other organism during symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of a specific chemical on or near a second organism, where the two organisms are in a symbiotic interaction. GO:0052235 obsolete negative aerotaxis in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052235 negative aerotaxis within other organism during symbiotic interaction|negative aerotaxis in other organism during symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen within a second organism, where the two organisms are in a symbiotic interaction. GO:0052239 obsolete negative chemotaxis in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052239 negative chemotaxis within other organism during symbiotic interaction|negative chemotaxis in other organism during symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of a specific chemical within a second organism, where the two organisms are in a symbiotic interaction. CL:1000507 kidney tubule cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000507 CL:1000504 kidney medulla cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000504 CL:1000500 kidney interstitial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000500 UBERON:0007223 osseus cochlea biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007223 The osseous cochlea is the bony foundation that forms the small shell arrangement for the cochlear nerve. UBERON:0007220 late embryonic stage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007220 embryo late growth stage|fetal stage|embryo late (growth) stage|fetus|fetus stage|embryo late stage An embryo stage that covers late steps of the embryogenesis with a fully formed embryo still developing before birth or egg hatching. GO:0052230 modulation of intracellular transport in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052230 modulation of intracellular transport in other organism during symbiotic interaction|modulation of intracellular trafficking in other organism Any process in which an organism modulates the frequency, rate or extent of the directed movement of substances within the cell or cells of a second organism, where the two organisms are in a symbiotic interaction. GO:0052234 obsolete negative aerotaxis on or near other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052234 negative aerotaxis on or near other organism during symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen on or near a second organism, where the two organisms are in a symbiotic interaction. UBERON:0007228 vestibular nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007228 vestibular nucleus of eighth cranial nerve|vestibular nucleus of acoustic nerve|vestibular VIII nucleus A cranial nucleus for the vestibular nerve. [WP,unvetted]. GO:0052233 obsolete positive aerotaxis in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052233 positive aerotaxis within other organism during symbiotic interaction|positive aerotaxis in other organism during symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen within a second organism, where the two organisms are in a symbiotic interaction. GO:0052232 obsolete positive aerotaxis on or near other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052232 positive aerotaxis on or near other organism during symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen on or near a second organism, where the two organisms are in a symbiotic interaction. GO:0052231 obsolete modulation of phagocytosis in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052231 modulation of phagocytosis in other organism during symbiotic interaction OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in a second organism, where the two organisms are in a symbiotic interaction. GO:0052249 modulation of RNA levels in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052249 modulation of RNA levels in other organism during symbiotic interaction The alteration by an organism of the levels of RNA in a second organism, where the two organisms are in a symbiotic interaction. GO:0052248 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052248 GO:0052247 obsolete positive energy taxis in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052247 positive energy taxis within other organism during symbiotic interaction|positive energy taxis in other organism during symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism within a second organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction. GO:0052246 obsolete positive energy taxis on or near other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052246 positive energy taxis on or near other organism during symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism on or near a second organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction. UBERON:0007293 presumptive rhombomere 6 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007293 A presumptive structure that has the potential to develop into a rhombomere 6. UBERON:0007292 presumptive rhombomere 5 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007292 A presumptive structure that has the potential to develop into a rhombomere 5. UBERON:0007291 presumptive rhombomere 4 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007291 A presumptive structure that has the potential to develop into a rhombomere 4. UBERON:0007290 presumptive rhombomere 3 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007290 A presumptive structure that has the potential to develop into a rhombomere 3. GO:1904002 regulation of sebum secreting cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904002 regulation of sebocyte proliferation Any process that modulates the frequency, rate or extent of sebum secreting cell proliferation. GO:1904001 obsolete positive regulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904001 positive regulation of pyrimidine salvage by positive regulation of transcription from RNA polymerase II promoter|activation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter|up-regulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter|up regulation of pyrimidine salvage by positive regulation of transcription from RNA polymerase II promoter|upregulation of pyrimidine salvage by positive regulation of transcription from RNA polymerase II promoter|up regulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter|up-regulation of pyrimidine salvage by positive regulation of transcription from RNA polymerase II promoter|upregulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter|activation of pyrimidine salvage by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of pyrimidine-containing compound salvage. GO:1904000 positive regulation of eating behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904000 up regulation of eating behaviour|upregulation of eating behavior|upregulation of eating behaviour|up regulation of eating behavior|activation of eating behavior|up-regulation of eating behaviour|activation of eating behaviour|up-regulation of eating behavior|positive regulation of eating behaviour Any process that activates or increases the frequency, rate or extent of eating behavior. UBERON:0007298 pronephric proximal convoluted tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007298 A proximal convoluted tubule that is part of a pronephros. UBERON:0007297 presumptive pronephric mesoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007297 nephron primordium A presumptive structure that has the potential to develop into a pronephric mesoderm. UBERON:0007296 presumptive rhombomere 2 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007296 A presumptive structure that has the potential to develop into a rhombomere 2. UBERON:0007295 presumptive rhombomere 8 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007295 A presumptive structure that has the potential to develop into a rhombomere 8. UBERON:0007294 presumptive rhombomere 7 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007294 A presumptive structure that has the potential to develop into a rhombomere 7. GO:0052241 obsolete positive chemotaxis on or near other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052241 positive chemotaxis on or near other organism during symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of a specific chemical on or near a second organism, where the two organisms are in a symbiotic interaction. GO:0052240 obsolete positive chemotaxis in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052240 positive chemotaxis within other organism during symbiotic interaction|positive chemotaxis in other organism during symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of a specific chemical within a second organism, where the two organisms are in a symbiotic interaction. GO:0052245 obsolete negative energy taxis on or near other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052245 negative energy taxis on or near other organism during symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism on or near a second organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction. GO:0052244 obsolete negative energy taxis in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052244 negative energy taxis within other organism during symbiotic interaction|negative energy taxis in other organism during symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism within a second organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction. GO:0052243 obsolete chemotaxis on or near other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052243 chemotaxis on or near other organism during symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism in response to a specific chemical concentration gradient on or near a second organism, where the two organisms are in a symbiotic interaction. GO:0052242 obsolete chemotaxis in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052242 chemotaxis within other organism during symbiotic interaction|chemotaxis in other organism during symbiotic interaction OBSOLETE. The directed movement of a motile cell or organism in response to a specific chemical concentration gradient within a second organism, where the two organisms are in a symbiotic interaction. GO:0052259 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052259 GO:0052258 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052258 GO:0052257 obsolete pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052257 general elicitor-dependent induction of innate immunity of other organism|pathogen-associated molecular pattern dependent induction by organism of innate immunity of other organism during symbiotic interaction|PAMP-dependent induction of innate immunity of other organism|general elicitor dependent induction of innate immunity of other organism|MAMP-dependent induction of innate immunity of other organism|pathogen-associated molecular pattern dependent induction by organism of innate immunity of other organism involved in symbiotic interaction|PAMP dependent induction of innate immunity of other organism|MAMP dependent induction of innate immunity of other organism OBSOLETE. Any process that involves recognition of a pathogen-associated molecular pattern, and by which an organism activates, maintains or increases the frequency, rate or extent of the innate immune response of a second organism, where the two organisms are in a symbiotic interaction. UBERON:0007282 presumptive segmental plate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007282 presumptive segmental plates A presumptive structure that has the potential to develop into a presomitic mesoderm. GO:1904009 cellular response to monosodium glutamate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904009 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosodium glutamate stimulus. UBERON:0007281 presumptive midbrain hindbrain boundary biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007281 presumptive midbrain-hindbrain boundary|presumptive MHB Embryonic structure that gives rise to the midbrain hindbrain boundary. UBERON:0007280 presumptive endocardium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007280 A presumptive structure that has the potential to develop into a endocardium. GO:1904008 response to monosodium glutamate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904008 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosodium glutamate stimulus. GO:1904007 positive regulation of phospholipase D activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904007 upregulation of phosphatidylcholine phosphatidohydrolase activity|positive regulation of choline phosphatase activity|upregulation of phospholipase D activity|upregulation of lecithinase D activity|up regulation of choline phosphatase activity|up regulation of lipophosphodiesterase II activity|positive regulation of lipophosphodiesterase II activity|activation of lipophosphodiesterase II activity|up regulation of phosphatidylcholine phosphatidohydrolase activity|up-regulation of phospholipase D activity|up-regulation of lecithinase D activity|activation of phospholipase D activity|activation of phosphatidylcholine phosphatidohydrolase activity|activation of lecithinase D activity|positive regulation of phosphatidylcholine phosphatidohydrolase activity|upregulation of choline phosphatase activity|up-regulation of lipophosphodiesterase II activity|positive regulation of lecithinase D activity|up-regulation of choline phosphatase activity|up-regulation of phosphatidylcholine phosphatidohydrolase activity|activation of choline phosphatase activity|up regulation of phospholipase D activity|up regulation of lecithinase D activity|upregulation of lipophosphodiesterase II activity Any process that activates or increases the frequency, rate or extent of phospholipase D activity. GO:1904006 negative regulation of phospholipase D activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904006 down regulation of lipophosphodiesterase II activity|down regulation of phospholipase D activity|down regulation of lecithinase D activity|inhibition of lecithinase D activity|inhibition of phospholipase D activity|downregulation of lipophosphodiesterase II activity|down regulation of phosphatidylcholine phosphatidohydrolase activity|downregulation of choline phosphatase activity|downregulation of phosphatidylcholine phosphatidohydrolase activity|down regulation of choline phosphatase activity|down-regulation of lipophosphodiesterase II activity|negative regulation of lipophosphodiesterase II activity|inhibition of choline phosphatase activity|down-regulation of phosphatidylcholine phosphatidohydrolase activity|negative regulation of phosphatidylcholine phosphatidohydrolase activity|inhibition of lipophosphodiesterase II activity|down-regulation of phospholipase D activity|down-regulation of lecithinase D activity|negative regulation of lecithinase D activity|inhibition of phosphatidylcholine phosphatidohydrolase activity|downregulation of lecithinase D activity|downregulation of phospholipase D activity|negative regulation of choline phosphatase activity|down-regulation of choline phosphatase activity Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase D activity. GO:1904005 regulation of phospholipase D activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904005 regulation of lipophosphodiesterase II activity|regulation of phosphatidylcholine phosphatidohydrolase activity|regulation of choline phosphatase activity|regulation of lecithinase D activity Any process that modulates the frequency, rate or extent of phospholipase D activity. GO:1904004 positive regulation of sebum secreting cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904004 upregulation of sebocyte proliferation|up-regulation of sebum secreting cell proliferation|activation of sebum secreting cell proliferation|up-regulation of sebocyte proliferation|up regulation of sebum secreting cell proliferation|activation of sebocyte proliferation|positive regulation of sebocyte proliferation|up regulation of sebocyte proliferation|upregulation of sebum secreting cell proliferation Any process that activates or increases the frequency, rate or extent of sebum secreting cell proliferation. GO:1904003 negative regulation of sebum secreting cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904003 down regulation of sebocyte proliferation|inhibition of sebocyte proliferation|down-regulation of sebum secreting cell proliferation|down-regulation of sebocyte proliferation|negative regulation of sebocyte proliferation|downregulation of sebum secreting cell proliferation|down regulation of sebum secreting cell proliferation|inhibition of sebum secreting cell proliferation|downregulation of sebocyte proliferation Any process that stops, prevents or reduces the frequency, rate or extent of sebum secreting cell proliferation. GO:1904013 obsolete xenon atom binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1904013 OBSOLETE. Interacting selectively and non-covalently with xenon atom. GO:1904012 obsolete platinum binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1904012 OBSOLETE. Interacting selectively and non-covalently with platinum. UBERON:0007289 presumptive rhombomere 1 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007289 A presumptive structure that has the potential to develop into a rhombomere 1. GO:1904011 cellular response to Aroclor 1254 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904011 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an Aroclor 1254 stimulus. UBERON:0007288 presumptive forebrain midbrain boundary biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007288 A presumptive structure that has the potential to develop into a forebrain-midbrain boundary. GO:1904010 response to Aroclor 1254 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904010 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an Aroclor 1254 stimulus. UBERON:0007287 presumptive bulbus arteriosus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007287 A presumptive structure that has the potential to develop into a bulbus arteriosus. UBERON:0007286 presumptive floor plate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007286 A presumptive structure that has the potential to develop into a floor plate. UBERON:0007285 presumptive paraxial mesoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007285 future paraxial mesoderm|future paraxial mesenchyme The part of the blastula that has the potential to develop into a paraxial mesoderm. UBERON:0007284 presumptive neural plate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007284 prospective neuroectoderm|prospective vegetal ectoderm A presumptive structure that has the potential to develop into a neural plate. UBERON:0007283 presumptive shield biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007283 A presumptive structure that has the potential to develop into a primitive knot. GO:0052252 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052252 GO:0052251 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052251 GO:0052250 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052250 GO:0052256 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052256 GO:0052255 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052255 GO:0052254 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052254 GO:0052253 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052253 GO:0052269 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052269 GO:0052268 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052268 UBERON:0007271 appendage musculature biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007271 fin musculature Any collection of muscles that is part of an appendage. UBERON:0007270 pelvic appendage musculature biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007270 pelvic fin musculature Any collection of muscles that is part of a pelvic appendage. GO:1904019 epithelial cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904019 epithelial cell apoptosis|epitheliocyte apoptosis|epitheliocyte apoptotic process Any apoptotic process in an epithelial cell. GO:1904018 positive regulation of vasculature development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904018 upregulation of vasculature development|up regulation of vascular system development|positive regulation of vascular system development|up regulation of vasculature development|activation of vasculature development|activation of vascular system development|up-regulation of vascular system development|up-regulation of vasculature development|upregulation of vascular system development Any process that activates or increases the frequency, rate or extent of vasculature development. GO:1904017 cellular response to Thyroglobulin triiodothyronine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904017 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroglobulin triiodothyronine stimulus. GO:1904016 response to Thyroglobulin triiodothyronine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904016 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroglobulin triiodothyronine stimulus. GO:1904015 cellular response to serotonin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904015 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus. GO:1904014 response to serotonin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904014 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus. GO:1904024 negative regulation of glucose catabolic process to lactate via pyruvate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904024 negative regulation of homolactic fermentation|down-regulation of homolactic fermentation|negative regulation of homofermentative lactate fermentation|down-regulation of homofermentative lactate fermentation|inhibition of homofermentation|downregulation of homofermentative pathway|down regulation of glucose fermentation to lactate via pyruvate|inhibition of glucose catabolic process to lactate via pyruvate|down regulation of homofermentative pathway|inhibition of glucose fermentation to lactate via pyruvate|downregulation of homolactate fermentation|inhibition of homofermentative lactate fermentation|inhibition of homolactic fermentation|inhibition of homofermentative pathway|down regulation of homolactate fermentation|inhibition of homolactate fermentation|down regulation of glucose catabolic process to lactate via pyruvate|negative regulation of homofermentation|down-regulation of homofermentation|down regulation of homolactic fermentation|down regulation of homofermentative lactate fermentation|downregulation of glucose catabolic process to lactate via pyruvate|down-regulation of glucose fermentation to lactate via pyruvate|negative regulation of glucose fermentation to lactate via pyruvate|downregulation of homolactic fermentation|downregulation of homofermentative lactate fermentation|down-regulation of homofermentative pathway|negative regulation of homofermentative pathway|downregulation of homofermentation|down-regulation of glucose catabolic process to lactate via pyruvate|down-regulation of homolactate fermentation|negative regulation of homolactate fermentation|down regulation of homofermentation|downregulation of glucose fermentation to lactate via pyruvate Any process that stops, prevents or reduces the frequency, rate or extent of glucose catabolic process to lactate via pyruvate. UBERON:0007279 presumptive atrioventricular canal biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007279 future atrioventricular canal|future AV canal A presumptive structure that has the potential to develop into a atrioventricular canal. GO:1904023 regulation of glucose catabolic process to lactate via pyruvate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904023 regulation of glucose fermentation to lactate via pyruvate|regulation of homofermentative pathway|regulation of homolactate fermentation|regulation of homolactic fermentation|regulation of homofermentative lactate fermentation|regulation of homofermentation Any process that modulates the frequency, rate or extent of glucose catabolic process to lactate via pyruvate. UBERON:0007278 presumptive sinus venosus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007278 Portion of tissue that is part of the heart tube and will become the sinus venosus. UBERON:0007277 presumptive hindbrain biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007277 rhombencephalon|embryonic rhombencephalon|presumptive rhombencephalon|future hindbrain The rhombencephalon (or hindbrain) is a developmental categorization of portions of the central nervous system in vertebrates. The rhombencephalon can be subdivided in a variable number of transversal swellings called rhombomeres. In the human embryo eight rhombomeres can be distinguished, from caudal to rostral: Rh7-Rh1 and the isthmus (the most rostral rhombomere). A rare disease of the rhombencephalon, 'rhombencephalosynapsis' is characterized by a missing vermis resulting in a fused cerebellum. Patients generally present with cerebellar ataxia. The caudal rhombencephalon has been generally considered as the initiation site for neural tube closure. GO:1904022 positive regulation of G protein-coupled receptor internalization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904022 up regulation of G-protein coupled receptor internalization|upregulation of G-protein coupled receptor internalization|positive regulation of G-protein coupled receptor internalization|up-regulation of G-protein coupled receptor internalization|activation of G-protein coupled receptor internalization Any process that activates or increases the frequency, rate or extent of G protein-coupled receptor internalization. GO:1904021 negative regulation of G protein-coupled receptor internalization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904021 downregulation of G-protein coupled receptor internalization|down regulation of G-protein coupled receptor internalization|inhibition of G-protein coupled receptor internalization|negative regulation of G-protein coupled receptor internalization|down-regulation of G-protein coupled receptor internalization Any process that stops, prevents or reduces the frequency, rate or extent of G protein-coupled receptor internalization. GO:1904020 regulation of G protein-coupled receptor internalization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904020 regulation of G-protein-coupled receptor internalization Any process that modulates the frequency, rate or extent of G protein-coupled receptor internalization. UBERON:0007273 pelvic appendage skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007273 The collection of all skeletal elements in a pelvic appendage region. UBERON:0007272 pectoral appendage skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007272 cheiropterygium Skeletal subdivision consisting of the anterior appendicular limb skeleton, excluding the pectoral girdle. GO:0052263 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052263 GO:0052262 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052262 GO:0052261 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052261 GO:0052260 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052260 GO:0052267 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052267 GO:0052266 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052266 GO:0052265 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052265 GO:0052264 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052264 GO:0052279 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052279 GO:1904029 regulation of cyclin-dependent protein kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904029 Any process that modulates the frequency, rate or extent of cyclin-dependent protein kinase activity. GO:1904028 positive regulation of collagen fibril organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904028 up-regulation of collagen fibril organization|activation of collagen fibril organization|up-regulation of fibrillar collagen organization|positive regulation of collagen fibril organisation|up regulation of collagen fibril organisation|upregulation of fibrillar collagen organization|up regulation of collagen fibril organization|upregulation of collagen fibril organisation|up regulation of fibrillar collagen organization|upregulation of collagen fibril organization|positive regulation of fibrillar collagen organization|activation of fibrillar collagen organization|up-regulation of collagen fibril organisation|activation of collagen fibril organisation Any process that activates or increases the frequency, rate or extent of collagen fibril organization. GO:1904027 negative regulation of collagen fibril organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904027 negative regulation of collagen fibril organisation|down-regulation of collagen fibril organisation|inhibition of fibrillar collagen organization|down-regulation of collagen fibril organization|downregulation of collagen fibril organisation|down regulation of collagen fibril organisation|inhibition of collagen fibril organisation|down regulation of fibrillar collagen organization|downregulation of collagen fibril organization|downregulation of fibrillar collagen organization|down regulation of collagen fibril organization|inhibition of collagen fibril organization|negative regulation of fibrillar collagen organization|down-regulation of fibrillar collagen organization Any process that stops, prevents or reduces the frequency, rate or extent of collagen fibril organization. GO:1904026 regulation of collagen fibril organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904026 regulation of collagen fibril organisation|regulation of fibrillar collagen organization|regulation of collagen fibrillogenesis Any process that modulates the frequency, rate or extent of collagen fibril organization. GO:1904025 positive regulation of glucose catabolic process to lactate via pyruvate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904025 positive regulation of homolactate fermentation|upregulation of homofermentation|up regulation of homolactate fermentation|up-regulation of glucose catabolic process to lactate via pyruvate|upregulation of glucose fermentation to lactate via pyruvate|up-regulation of homofermentative lactate fermentation|up-regulation of homolactic fermentation|upregulation of homofermentative pathway|activation of homofermentation|up-regulation of homofermentation|upregulation of glucose catabolic process to lactate via pyruvate|upregulation of homolactate fermentation|up-regulation of glucose fermentation to lactate via pyruvate|activation of glucose fermentation to lactate via pyruvate|upregulation of homofermentative lactate fermentation|upregulation of homolactic fermentation|activation of homofermentative pathway|up-regulation of homofermentative pathway|positive regulation of homofermentation|up-regulation of homolactate fermentation|activation of homolactate fermentation|up regulation of glucose catabolic process to lactate via pyruvate|up regulation of homofermentation|activation of glucose catabolic process to lactate via pyruvate|up regulation of homolactic fermentation|up regulation of homofermentative lactate fermentation|positive regulation of glucose fermentation to lactate via pyruvate|activation of homolactic fermentation|activation of homofermentative lactate fermentation|positive regulation of homofermentative pathway|up regulation of glucose fermentation to lactate via pyruvate|positive regulation of homolactic fermentation|positive regulation of homofermentative lactate fermentation|up regulation of homofermentative pathway Any process that activates or increases the frequency, rate or extent of glucose catabolic process to lactate via pyruvate. GO:1904035 regulation of epithelial cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904035 regulation of epithelial cell apoptosis|regulation of epitheliocyte apoptosis|regulation of epitheliocyte apoptotic process Any process that modulates the frequency, rate or extent of epithelial cell apoptotic process. GO:1904034 positive regulation of t-SNARE clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904034 up regulation of t-SNARE clustering|upregulation of t-SNARE clustering|up-regulation of t-SNARE clustering|activation of t-SNARE clustering Any process that activates or increases the frequency, rate or extent of t-SNARE clustering. UBERON:0007267 trachea pre-cartilage rings biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007267 A pre-cartilage condensation that is part of a trachea. GO:1904033 negative regulation of t-SNARE clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904033 down-regulation of t-SNARE clustering|downregulation of t-SNARE clustering|down regulation of t-SNARE clustering|inhibition of t-SNARE clustering Any process that stops, prevents or reduces the frequency, rate or extent of t-SNARE clustering. GO:1904032 regulation of t-SNARE clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904032 Any process that modulates the frequency, rate or extent of t-SNARE clustering. GO:1904031 positive regulation of cyclin-dependent protein kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904031 up-regulation of cyclin-dependent protein kinase activity|activation of cyclin-dependent protein kinase activity|up regulation of cyclin-dependent protein kinase activity|upregulation of cyclin-dependent protein kinase activity Any process that activates or increases the frequency, rate or extent of cyclin-dependent protein kinase activity. GO:0052270 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052270 GO:1904030 negative regulation of cyclin-dependent protein kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904030 down-regulation of cyclin-dependent protein kinase activity|downregulation of cyclin-dependent protein kinase activity|down regulation of cyclin-dependent protein kinase activity|inhibition of cyclin-dependent protein kinase activity Any process that stops, prevents or reduces the frequency, rate or extent of cyclin-dependent protein kinase activity. GO:0052274 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052274 GO:0052273 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052273 GO:0052272 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052272 GO:0052271 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052271 GO:0052278 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052278 GO:0052277 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052277 GO:0052276 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052276 UBERON:0007269 pectoral appendage musculature biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007269 pectoral fin musculature|pectoral fin muscle Any collection of muscles that is part of a pectoral appendage. GO:0052275 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052275 GO:0042802 identical protein binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0042802 isoform-specific homophilic binding|protein homopolymerization Interacting selectively and non-covalently with an identical protein or proteins. GO:0042801 obsolete polo kinase kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042801 OBSOLETE. Catalysis of the addition of a phosphate group onto a serine or threonine residue in any member of the polo kinase class of proteins. GO:0042804 obsolete protein homooligomerization activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042804 protein homooligomerization activity|oligomerization activity OBSOLETE. Interacting selectively with identical proteins to form a homooligomer. GO:0042803 protein homodimerization activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0042803 dimerization activity Interacting selectively and non-covalently with an identical protein to form a homodimer. GO:0042800 histone methyltransferase activity (H3-K4 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042800 Reactome:R-HSA-8937016|Reactome:R-HSA-3364026|Reactome:R-HSA-8865498|Reactome:R-HSA-8936481|Reactome:R-HSA-1214188|Reactome:R-HSA-8936621|Reactome:R-HSA-8937050 histone H3 lysine 4-specific methyltransferase activity|histone lysine N-methyltransferase activity (H3-K4 specific)|histone methylase activity (H3-K4 specific) Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 4) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 4). This reaction is the addition of a methyl group onto lysine at position 4 of the histone H3 protein. CHEBI:30367 pyrazol-1-ide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30367 CHEBI:78301 dTDP-beta-L-rhodosamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78301 GO:0042809 vitamin D receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042809 calciferol receptor binding|VDR binding Interacting selectively and non-covalently with the vitamin D receptor, a nuclear receptor that mediates the action of vitamin D by binding DNA and controlling the transcription of hormone-sensitive genes. CHEBI:30366 imidazolide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30366 GO:0042806 fucose binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042806 Interacting selectively and non-covalently with fucose, the pentose 6-deoxygalactose. CHEBI:30363 isobutane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30363 GO:0042805 actinin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042805 capZ binding|beta-actinin binding Interacting selectively and non-covalently with actinin, any member of a family of proteins that crosslink F-actin. CHEBI:30362 isopentane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30362 GO:0042808 obsolete neuronal Cdc2-like kinase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042808 neuronal Cdc2-like kinase binding OBSOLETE. Interacting selectively and non-covalently with neuronal Cdc2-like kinase, an enzyme involved in the regulation of neuronal differentiation and neuro-cytoskeleton dynamics. CHEBI:78303 aclacinomycin S zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78303 GO:0042807 central vacuole biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042807 A membrane-enclosed sac that takes up most of the volume of a mature plant cell. Functions include storage, separation of toxic byproducts, and cell growth determination. CHEBI:78302 dTDP-2-deoxy-beta-L-fucose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78302 GO:0003205 cardiac chamber development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003205 The progression of a cardiac chamber over time, from its formation to the mature structure. A cardiac chamber is an enclosed cavity within the heart. GO:0003204 cardiac skeleton development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003204 heart fibrous skeleton development The progression of the cardiac skeleton over time, from its formation to the mature structure. The cardiac skeleton is a specialized extracellular matrix that separates the atria from the ventricles and provides physical support for the heart. GO:0003207 cardiac chamber formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003207 heart chamber formation The developmental process pertaining to the initial formation of a cardiac chamber from unspecified parts. A cardiac chamber is an enclosed cavity within the heart. CHEBI:78318 pppGp(2'->5')A(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78318 GO:0003206 cardiac chamber morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003206 heart chamber morphogenesis The process in which a cardiac chamber is generated and organized. A cardiac chamber is an enclosed cavity within the heart. GO:0003201 epithelial to mesenchymal transition involved in coronary vasculature morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003201 A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the shaping of the coronary vasculature. GO:0003200 endocardial cushion to mesenchymal transition involved in heart chamber septation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003200 A transition where an endocardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of the heart septum. GO:0003203 endocardial cushion morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003203 The process in which the anatomical structure of the endocardial cushion is generated and organized. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. GO:0003202 endocardial cushion to mesenchymal transition involved in cardiac skeleton development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003202 A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will give rise to the cardiac skeleton. CHEBI:112505 2-amino-3-hydroxy-4-methylbenzoyl-AMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_112505 GO:0042813 Wnt-activated receptor activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0042813 frizzled-2 receptor activity|frizzled receptor activity|Wnt receptor activity Combining with a Wnt protein and transmitting the signal across the plasma membrane to initiate a change in cell activity. GO:0042812 pheromone catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042812 pheromone catabolism|pheromone degradation|pheromone breakdown The chemical reactions and pathways resulting in the breakdown of pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process. GO:0042815 bipolar cell growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042815 bipolar cell elongation|polar cell elongation|bipolar growth The process in which a cell irreversibly increases in size along one axis through simultaneous polarized growth from opposite ends of a cell, resulting in morphogenesis of the cell. GO:0042814 monopolar cell growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042814 monopolar growth|polar cell elongation|monopolar cell elongation Polarized growth from one end of a cell. GO:0042811 pheromone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042811 pheromone biosynthesis|pheromone anabolism|pheromone synthesis|pheromone formation The chemical reactions and pathways resulting in the formation of pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process. GO:0042810 pheromone metabolic process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0042810 pheromone metabolism The chemical reactions and pathways involving pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process. CHEBI:78312 5,10-dihydrophenazine-1-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78312 CHEBI:78311 15-oxolipoxin A4(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78311 GO:0003209 cardiac atrium morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003209 The process in which the cardiac atrium is generated and organized. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle. GO:0042817 pyridoxal metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042817 pyridoxal metabolism The chemical reactions and pathways involving 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate. GO:0042816 vitamin B6 metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042816 vitamin B6 metabolism The chemical reactions and pathways involving any of the vitamin B6 compounds: pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate. GO:0003208 cardiac ventricle morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003208 The process in which the cardiac ventricle is generated and organized. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart. GO:0042819 vitamin B6 biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042819 vitamin B6 biosynthesis|vitamin B6 anabolism|pyridoxine-5'-phosphate biosynthesis|vitamin B6 synthesis|vitamin B6 formation The chemical reactions and pathways resulting in the formation of any of the vitamin B6 compounds; pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate. CHEBI:78314 4-O-dimethylallyl-L-tyrosine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78314 GO:0042818 pyridoxamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042818 pyridoxamine metabolism The chemical reactions and pathways involving 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate. CHEBI:78313 5,10-dihydro-9-dimethylallylphenazine 1-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78313 CHEBI:78329 13,14-dihydrolipoxin A4(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78329 CHEBI:78328 scutellarein(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78328 CHEBI:30347 ethylenediamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30347 CHEBI:29356 oxide(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29356 CHEBI:44992 2-aminopteridin-4(3H)-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_44992 GO:0042824 MHC class I peptide loading complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0042824 peptide-loading complex|PLC A large, multisubunit complex which consists of the MHC class I-beta 2 microglobulin dimer, the transporter associated with antigen presentation (TAP), tapasin (an MHC-encoded membrane protein), the chaperone calreticulin and the thiol oxidoreductase ERp57. Functions in the assembly of peptides with newly synthesized MHC class I molecules. GO:0042823 pyridoxal phosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042823 MetaCyc:PWY0-845 pyridoxal phosphate biosynthesis|active vitamin B6 biosynthetic process|active vitamin B6 biosynthesis|pyridoxal phosphate anabolism|pyridoxal phosphate synthesis|pyridoxal phosphate formation The chemical reactions and pathways resulting in the formation of pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6. GO:0042826 histone deacetylase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042826 Interacting selectively and non-covalently with the enzyme histone deacetylase. GO:0042825 TAP complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042825 transporter associated with antigen presentation A heterodimer composed of the subunits TAP1 and TAP2 (transporter associated with antigen presentation). Functions in the transport of antigenic peptides from the cytosol to the lumen of the endoplasmic reticulum. CHEBI:29360 methanediide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29360 GO:0042820 vitamin B6 catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042820 vitamin B6 catabolism|vitamin B6 degradation|vitamin B6 breakdown The chemical reactions and pathways resulting in the breakdown of any of the vitamin B6 compounds; pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate. GO:0042822 pyridoxal phosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042822 pyridoxal phosphate metabolism|active vitamin B6 metabolism|active vitamin B6 metabolic process The chemical reactions and pathways involving pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6. GO:0042821 pyridoxal biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042821 pyridoxal biosynthesis|pyridoxal anabolism|pyridoxal synthesis|pyridoxal formation The chemical reactions and pathways resulting in the formation of 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, one of the vitamin B6 compounds. CHEBI:78320 2-hydroxypropanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78320 CHEBI:78327 pseudobaptigenin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78327 GO:0042828 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042828 GO:0042827 platelet dense granule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042827 bull's eye body|platelet dense body Electron-dense granule occurring in blood platelets that stores and secretes adenosine nucleotides and serotonin. They contain a highly condensed core consisting of serotonin, histamine, calcium, magnesium, ATP, ADP, pyrophosphate and membrane lysosomal proteins. CHEBI:78326 5-hydroxyxanthotoxin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78326 CHEBI:78325 13,14-dihydro-15-oxolipoxin A4(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78325 CHEBI:78324 baicalein(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78324 GO:0042829 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042829 CHEBI:29369 peroxy group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29369 GO:0042835 BRE binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042835 Interacting selectively and non-covalently with the RNA element BRE (Bruno response element). GO:0042834 peptidoglycan binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042834 Interacting selectively and non-covalently, in a non-covalent manner, with peptidoglycan, any of a class of glycoconjugates found in bacterial cell walls. GO:0042837 D-glucarate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042837 D-glucarate biosynthesis|saccharate biosynthetic process|saccharate biosynthesis|D-glucarate anabolism|D-glucarate synthesis|D-glucarate formation The chemical reactions and pathways resulting in the formation of D-glucarate, the D-enantiomer of glucarate. GO:0042836 D-glucarate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042836 saccharate metabolic process|D-glucarate metabolism|saccharate metabolism The chemical reactions and pathways involving D-glucarate, the D-enantiomer of glucarate. D-glucarate is derived from either D-glucose or L-gulose. GO:0042831 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042831 GO:0042830 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042830 GO:0042833 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042833 GO:0042832 defense response to protozoan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042832 defense response to protozoan, incompatible interaction|defence response to protozoon|defense response to pathogenic protozoa|resistance response to pathogenic protozoan|resistance response to pathogenic protozoa|defence response to protozoa|defense response to protozoon|defence response to pathogenic protozoa|defense response to protozoa Reactions triggered in response to the presence of a protozoan that act to protect the cell or organism. CHEBI:30356 isobutyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30356 CHEBI:30353 isopropyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30353 CHEBI:78338 wogonin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78338 GO:0042839 D-glucuronate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042839 D-glucuronate metabolism The chemical reactions and pathways involving D-glucuronate, the D-enantiomer of glucuronate. GO:0042838 D-glucarate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042838 D-glucarate degradation|D-glucarate catabolism|saccharate catabolism|D-glucarate breakdown|saccharate catabolic process The chemical reactions and pathways resulting in the breakdown of D-glucarate, the D-enantiomer of glucarate. CHEBI:29337 azanide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29337 GO:0042840 D-glucuronate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042840 D-glucuronate catabolism|D-glucuronate degradation|D-glucuronate breakdown The chemical reactions and pathways resulting in the breakdown of D-glucuronate, the D-enantiomer of glucuronate. GO:0042846 glycol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042846 dihydric alcohol catabolism|glycol degradation|glycol breakdown|glycol catabolism|dihydric alcohol catabolic process The chemical reactions and pathways resulting in the breakdown of glycol, a diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent. GO:0042845 glycol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042845 dihydric alcohol biosynthesis|dihydric alcohol biosynthetic process|glycol anabolism|glycol biosynthesis|glycol synthesis|glycol formation The chemical reactions and pathways resulting in the formation of glycol, a diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent. GO:0042848 sorbose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042848 sorbose catabolism|sorbose breakdown|sorbose degradation The chemical reactions and pathways resulting in the breakdown of sorbose, the ketohexose xylo-2-hexulose. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid. GO:0042847 sorbose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042847 sorbose biosynthesis|sorbose anabolism|sorbose synthesis|sorbose formation The chemical reactions and pathways resulting in the formation of sorbose, the ketohexose xylo-2-hexulose. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid. GO:0042842 D-xylose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042842 D-xylose anabolism|D-xylose synthesis|D-xylose formation|D-xylose biosynthesis The chemical reactions and pathways resulting in the formation of D-xylose, a naturally occurring plant polysaccharide. CHEBI:78341 1-(1Z-octadecenyl)-2-oleoyl-sn-glycero-3-phosphoserine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78341 GO:0042841 D-glucuronate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042841 D-glucuronate anabolism|D-glucuronate biosynthesis|D-glucuronate synthesis|D-glucuronate formation The chemical reactions and pathways resulting in the formation of D-glucuronate, the D-enantiomer of glucuronate. CHEBI:78340 1-(1Z-octadecenyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78340 GO:0042844 glycol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042844 dihydric alcohol metabolism|dihydric alcohol metabolic process|glycol metabolism The chemical reactions and pathways involving glycol, a diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent. GO:0042843 D-xylose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042843 D-xylose catabolism|D-xylose degradation|D-xylose breakdown The chemical reactions and pathways resulting in the breakdown of D-xylose, a naturally occurring plant polysaccharide. CHEBI:44976 phosphonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_44976 CHEBI:78345 D-ribofuranose-2,5-bisphosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78345 CHEBI:30322 3-acetamidopropanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30322 CHEBI:78343 1-(1Z-octadecenyl)-2-arachidonoyl-sn-glycero-3-phosphoserine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78343 CHEBI:78342 1-(1Z-octadecenyl)-2-arachidonoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78342 CHEBI:30320 thioacetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30320 CHEBI:78349 3-sulfinopropionyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78349 GO:0042849 L-sorbose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042849 L-sorbose biosynthesis|L-sorbose anabolism|L-sorbose synthesis|L-sorbose formation The chemical reactions and pathways resulting in the formation of L-sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose. L-sorbose is formed by bacterial oxidation of sorbitol. OBO:cl#lacks_plasma_membrane_part lacks_plasma_membrane_part biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part lacks_plasma_membrane_part CHEBI:78347 3-linalylflaviolin-2-olate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78347 CHEBI:78346 D-ribofuranose 5-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78346 CHEBI:29348 fatty amide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29348 GO:0042851 L-alanine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042851 L-alanine metabolism The chemical reactions and pathways involving L-alanine, the L-enantiomer of 2-aminopropanoic acid, i.e. (2S)-2-aminopropanoic acid. CHEBI:44962 D-alpha-phenylglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_44962 CHEBI:29347 monocarboxylic acid amide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29347 GO:0042850 L-sorbose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042850 L-sorbose catabolism|L-sorbose degradation|L-sorbose breakdown The chemical reactions and pathways resulting in the breakdown of L-sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose. CHEBI:29340 hydridonitrate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29340 CHEBI:29343 azanediyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29343 GO:0042857 chrysobactin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042857 chrysobactin metabolism The chemical reactions and pathways involving the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine). GO:0042856 eugenol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042856 eugenol degradation|eugenic acid catabolic process|eugenol breakdown|4-allyl-2-methoxyphenol catabolism|4-allyl-2-methoxyphenol catabolic process|eugenol catabolism|eugenic acid catabolism The chemical reactions and pathways resulting in the breakdown of eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil. GO:0042859 chrysobactin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042859 chrysobactin degradation|chrysobactin breakdown|chrysobactin catabolism The chemical reactions and pathways resulting in the breakdown of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine). GO:0042858 chrysobactin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042858 chrysobactin biosynthetic process, peptide formation|chrysobactin anabolism|chrysobactin biosynthetic process, peptide modification|chrysobactin synthesis|chrysobactin biosynthesis|chrysobactin formation The chemical reactions and pathways resulting in the formation of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine). CHEBI:78352 cyclooctat-9-en-7-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78352 GO:0042853 L-alanine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042853 L-alanine degradation|L-alanine breakdown|L-alanine catabolism The chemical reactions and pathways resulting in the breakdown of L-alanine, the L-enantiomer of 2-aminopropanoic acid, i.e. (2S)-2-aminopropanoic acid. GO:0042852 L-alanine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042852 L-alanine biosynthesis|L-alanine anabolism|L-alanine synthesis|L-alanine formation The chemical reactions and pathways resulting in the formation of L-alanine, the L-enantiomer of 2-aminopropanoic acid, i.e. (2S)-2-aminopropanoic acid. GO:0042855 eugenol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042855 4-allyl-2-methoxyphenol biosynthetic process|4-allyl-2-methoxyphenol biosynthesis|eugenol anabolism|eugenol synthesis|eugenol biosynthesis|eugenol formation|eugenic acid biosynthetic process|eugenic acid biosynthesis The chemical reactions and pathways resulting in the formation of eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil. GO:0042854 eugenol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042854 eugenic acid metabolic process|eugenic acid metabolism|4-allyl-2-methoxyphenol metabolic process|4-allyl-2-methoxyphenol metabolism|eugenol metabolism The chemical reactions and pathways involving eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil. CHEBI:78355 1-(1Z-alkenyl)-2-acyl-sn-glycero-3-phospho-L-serine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78355 UBERON:0007329 pancreatic duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007329 ductus pancreaticus|pancreas duct|duct of pancreas A duct that collects and carries secretions of the exocrine pancreas to the intestine. CHEBI:78358 Delta(4)-dafachronate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78358 CHEBI:78357 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78357 UBERON:0007324 pancreatic lobule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007324 pancreas lobe|lobulus pancreaticus|pancreatic lobule A dense accumulation of exocrine glands in the pancreas often surrounding islets of Langerhans. PR:000016542 type 1B DNA topoisomerase 1 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000016542 TOP1|DNA topoisomerase I|Top-1 A protein that is a translation product of the human TOP1 gene or a 1:1 ortholog thereof. CHEBI:30308 meso-2,6-diaminopimelate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30308 CHEBI:30306 1,3-dihydroxy-N-methylacridone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30306 CHEBI:30305 N-methylanthraniloyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30305 CHEBI:29317 selanide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29317 GO:0042860 achromobactin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042860 achromobactin metabolism The chemical reactions and pathways involving achromobactin, a citrate siderophore. GO:0042862 achromobactin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042862 achromobactin degradation|achromobactin breakdown|achromobactin catabolism The chemical reactions and pathways resulting in the breakdown of achromobactin, a citrate siderophore. CHEBI:44951 dioxidophosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_44951 GO:0042861 achromobactin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042861 achromobactin anabolism|achromobactin biosynthesis|achromobactin synthesis|achromobactin formation|achromobactin biosynthetic process, peptide formation|achromobactin biosynthetic process, peptide modification The chemical reactions and pathways resulting in the formation of achromobactin, a citrate siderophore. GO:0042868 antisense RNA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042868 antisense RNA metabolism The chemical reactions and pathways involving antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis. GO:0042867 pyruvate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042867 pyruvate degradation|pyruvate breakdown|pyruvate catabolism The chemical reactions and pathways resulting in the breakdown of pyruvate, 2-oxopropanoate. GO:0042869 aldarate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042869 aldarate transport The process in which aldarate is transported across a lipid bilayer, from one side of a membrane to the other. GO:0042864 pyochelin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042864 pyochelin anabolism|pyochelin synthesis|pyochelin formation|pyochelin biosynthetic process, peptide formation|pyochelin biosynthetic process, peptide modification|pyochelin biosynthesis The chemical reactions and pathways resulting in the formation of the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid). GO:0042863 pyochelin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042863 pyochelin metabolism The chemical reactions and pathways involving the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid). GO:0042866 pyruvate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042866 pyruvate biosynthesis|pyruvate anabolism|pyruvate synthesis|pyruvate formation The chemical reactions and pathways resulting in the formation of pyruvate, 2-oxopropanoate. CHEBI:78361 lichen metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78361 GO:0042865 pyochelin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042865 pyochelin degradation|pyochelin catabolism|pyochelin breakdown The chemical reactions and pathways resulting in the breakdown of the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid). CHEBI:78367 1-hexadecyl-2-propionyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78367 CHEBI:78366 EC 2.7.1.1 (hexokinase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78366 CHEBI:78369 1-hexadecyl-2-succinyl-sn-glycero-3-phosphocholine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78369 CHEBI:78368 1-hexadecyl-2-butanoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78368 CHEBI:30318 (S)-dihydrolipoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30318 CHEBI:30316 dihydrolipoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30316 CHEBI:30314 (R)-lipoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30314 CHEBI:30313 lipoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30313 CHEBI:29323 methylazoxymethanol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29323 GO:0042871 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042871 GO:0042870 D-glucarate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042870 D-glucarate transport The process in which D-glucarate, the D-enantiomer of glucarate, is transported across a lipid bilayer, from one side of a membrane to the other. GO:0042873 aldonate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042873 aldonate transport The process in which aldonate is transported across a lipid bilayer, from one side of a membrane to the other. GO:0042872 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042872 GO:0042879 aldonate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042879 Enables the transfer of aldonate from one side of a membrane to the other. CHEBI:78370 cyclooctatin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78370 UBERON:0007301 appendage blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007301 fin blood vessel|limb blood vessel A blood vessel that is part of a limb/fin. UBERON:0007300 pectoral appendage blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007300 pectoral fin blood vessel A blood vessel that is part of a pectoral appendage. GO:0042878 D-glucarate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042878 Enables the transfer of D-glucarate, the D-enantiomer of glucarate, from one side of a membrane to the other. GO:0042875 D-galactonate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042875 D-galactonate transport The process in which D-galactonate, the D-enantiomer of galactonate, is transported across a lipid bilayer, from one side of a membrane to the other. GO:0042874 D-glucuronate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042874 D-glucuronate transport The process in which D-glucuronate, the D-enantiomer of glucuronate, is transported across a lipid bilayer, from one side of a membrane to the other. GO:0042877 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042877 CHEBI:78372 EC 3.1.1.5 (lysophospholipase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78372 GO:0042876 aldarate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042876 Enables the transfer of aldarate from one side of a membrane to the other. CHEBI:78371 1-hexadecyl-2-glutaryl-sn-glycero-3-phosphocholine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78371 CHEBI:78378 2-deoxy-alpha-L-fucosylaclacinomycin S zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78378 CHEBI:78377 EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78377 UBERON:0007307 pronephric glomerular basement membrane biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007307 pronephric glomerular filtration membrane A glomerular basement membrane that is part of a pronephros. CHEBI:78376 2-hydroxy-7-methoxy-5-methyl-1-naphthoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78376 UBERON:0007306 pronephric glomerular capillary biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007306 A glomerular capillary that is part of a pronephros. CHEBI:78375 N(5)-phenyl-L-glutamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78375 OIO:hasScope has_scope biolink:OntologyClass go-plus http://www.geneontology.org/formats/oboInOwl#hasScope UBERON:0007304 appendage vasculature biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007304 fin vasculature A vasculature that is part of a limb/fin. UBERON:0007303 pharyngeal vasculature biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007303 branchial vasculature A vasculature that is part of a chordate pharynx. UBERON:0007302 pectoral appendage vasculature biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007302 pectoral fin vasculature A vasculature that is part of a pectoral appendage. CHEBI:78379 EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78379 GO:0003278 apoptotic process involved in heart morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003278 apoptosis involved in heart morphogenesis Any apoptotic process that contributes to the shaping of the heart. GO:0003277 apoptotic process involved in endocardial cushion morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003277 apoptosis involved in endocardial cushion morphogenesis Any apoptotic process that contributes to the shaping of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. GO:0003279 cardiac septum development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003279 heart septum development The progression of a cardiac septum over time, from its initial formation to the mature structure. GO:0003274 endocardial cushion fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003274 The cell-cell adhesion process of mesenchymal cardiac cushion cells that contributes to the process of cushion shaping. GO:0003273 cell migration involved in endocardial cushion formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003273 The orderly movement of a cell from one site to another that will contribute to the formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. GO:0003276 apoptotic process involved in heart valve morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003276 apoptosis involved in heart valve morphogenesis Any apoptotic process that contributes to the shaping of a heart valve. GO:0003275 apoptotic process involved in outflow tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003275 apoptosis involved in outflow tract morphogenesis Any apoptotic process that contributes to the shaping of the outflow tract. The outflow tract is the portion of the heart through which blood flows into the arteries. GO:0003270 Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003270 Notch signalling pathway involved in regulation of secondary heart field cardioblast proliferation|Notch signaling pathway involved in regulation of second heart field cardioblast proliferation The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell contributing to the modulation of the frequency, rate or extent of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. GO:0003272 endocardial cushion formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003272 The developmental process pertaining to the initial formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. GO:0003271 smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003271 smoothened receptor signaling pathway involved in regulation of second heart field cardioblast proliferation|hedgehog signaling pathway involved in regulation of second heart field cardioblast proliferation|smoothened receptor signalling pathway involved in regulation of secondary heart field cardioblast proliferation|hh signaling pathway involved in regulation of second heart field cardioblast proliferation|smoothened receptor signaling pathway involved in regulation of secondary heart field cardioblast proliferation The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened contributing to the modulation of the frequency, rate or extent of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. CHEBI:136568 (24S)-hydroxycholesterol 3,24-disulfate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136568 CHEBI:136567 (24S)-hydroxycholesterol 3-sulfate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136567 CHEBI:136566 (24S)-hydroxycholesterol 24-sulfate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136566 CHEBI:136565 (6R)-6-lactoyl-5,6,7,8-tetrahydropterin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136565 GO:0198738 cell-cell signaling by wnt biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0198738 Any process that mediates the transfer of information from one cell to another, medaited by a wnt family protein ligand. This process includes wnt signal transduction in the receiving cell, release of wnt ligand from a secreting cell as well as any processes that actively facilitate wnt transport and presentation to receptor on the recieving cell. CHEBI:136569 (4Z,7Z,13Z,16Z,19Z)-10,11-epoxydocosapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136569 CHEBI:136560 (4aR,10bS)-noroxomaritidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136560 CHEBI:136564 (R)-dyspropterin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136564 CHEBI:136563 (4Z,7Z,10Z,16Z,19Z)-13,14-epoxydocosapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136563 CHEBI:136562 long-chain fatty acyl-AMP(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136562 GO:0003289 atrial septum primum morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003289 The process in which anatomical structure of an atrial septum primum is generated and organized. GO:0003288 ventricular septum intermedium morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003288 The developmental process in which a ventricular septum intermedium is generated and organized. GO:0003285 septum secundum development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003285 The progression of the septum secundum over time, from its initial formation to the mature structure. GO:0003284 septum primum development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003284 The progression of the septum primum over time, from its formation to the mature structure. GO:0003287 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003287 GO:0003286 atrial septum intermedium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003286 The progression of the atrial septum intermedium over time, from its formation to the mature structure. GO:0003281 ventricular septum development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003281 interventricular septum development|septum inferius development The progression of the ventricular septum over time from its formation to the mature structure. GO:0003280 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003280 GO:0003283 atrial septum development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003283 The progression of the atrial septum over time, from its initial formation to the mature structure. GO:0003282 ventricular septum intermedium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003282 The progression of the ventricular septum intermedium over time, from its formation to the mature structure. CHEBI:136579 cholesterol sulfate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136579 GO:0003290 atrial septum secundum morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003290 The process in which anatomical structure of an atrial septum secundum is generated and organized. CHEBI:136576 (7Z,10Z,16Z,19Z)-13,14-epoxydocosatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136576 CHEBI:136570 (6R)-5,6,7,8-tetrahydrobiopterin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136570 CHEBI:136575 (7Z,10Z,13Z,19Z)-16,17-epoxydocosatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136575 CHEBI:136574 epoxydocosatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136574 CHEBI:136573 (7Z,10Z,13Z,16Z)-19,20-epoxydocosatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136573 CHEBI:136572 (6R)-5,10-methylenetetrahydrofolate poly(gamma-L-glutamate) macromolecule biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136572 GO:0003259 cardioblast anterior-lateral migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003259 The orderly movement of a cardioblast toward the head and laterally to form the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. GO:0003256 regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003256 Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the differentiation of a myocardial precursor cell. GO:0003255 endocardial precursor cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003255 The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of an endocardial precursor cell. A endocardial precursor cell is a cell that has been committed to a endocardial cell fate, but will undergo further cell divisions rather than terminally differentiate. GO:0003258 regulation of transcription from RNA polymerase II promoter involved in endocardial precursor cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003258 Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the differentiation of an endocardial precursor cell. GO:0003257 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003257 Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the differentiation of a myocardial precursor cell. GO:0003252 negative regulation of cell proliferation involved in heart valve morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003252 Any process that decreases the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve. GO:0003251 positive regulation of cell proliferation involved in heart valve morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003251 Any process that increases the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve. GO:0003254 regulation of membrane depolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003254 Any process that modulates the rate, frequency or extent of membrane depolarization. Membrane depolarization is the process in which membrane potential changes in the depolarizing direction from the resting potential, usually from negative to positive. GO:0003253 cardiac neural crest cell migration involved in outflow tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003253 The orderly movement of a neural crest cell from one site to another that will contribute to the morphogenesis of the outflow tract. GO:0003250 regulation of cell proliferation involved in heart valve morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003250 Any process that modulates the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve. CHEBI:136545 alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136545 CHEBI:136544 alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl(1-) group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136544 CHEBI:136543 (+)-sesamin dicatechol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136543 CHEBI:136542 (+)-sesamin monocatechol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136542 CHEBI:136541 (R)-2-(phosphonomethyl)malate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136541 GO:0003267 canonical Wnt signaling pathway involved in positive regulation of secondary heart field cardioblast proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003267 canonical Wnt receptor signalling pathway involved in positive regulation of secondary heart field cardioblast proliferation|canonical Wnt-activated signaling pathway involved in positive regulation of secondary heart field cardioblast proliferation|canonical Wnt receptor signaling pathway involved in positive regulation of second heart field cardioblast proliferation|canonical Wnt receptor signaling pathway involved in positive regulation of secondary heart field cardioblast proliferation A canonical Wnt signaling pathway that contributes to an increase in the frequency, or rate of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. GO:0003266 regulation of secondary heart field cardioblast proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003266 regulation of second heart field cardioblast proliferation|regulation of SHF cardioblast proliferation Any process that modulates the frequency, rate or extent of cardioblast proliferation in the second heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. The secondary heart field is the region of the heart that will form the majority of the mesodermal component of the right ventricle, the arterial pole (outflow tract) and the venous pole (inflow tract). GO:0003269 BMP signaling pathway involved in regulation of secondary heart field cardioblast proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003269 BMP signalling pathway involved in regulation of secondary heart field cardioblast proliferation|BMP signaling pathway involved in regulation of second heart field cardioblast proliferation A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the modulation of the frequency, rate or extent of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. GO:0003268 fibroblast growth factor receptor signaling pathway involved in regulation of secondary heart field cardioblast proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003268 fibroblast growth factor receptor signalling pathway involved in regulation of secondary heart field cardioblast cell proliferation|fibroblast growth factor receptor signaling pathway involved in regulation of second heart field cardioblast cell proliferation|fibroblast growth factor receptor signaling pathway involved in regulation of secondary heart field cardioblast cell proliferation The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands contributing to the modulation of the frequency, rate or extent of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. GO:0003263 cardioblast proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003263 The multiplication or reproduction of cardioblasts, resulting in the expansion of the population in the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. GO:0003262 endocardial progenitor cell migration to the midline involved in heart field formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003262 The orderly movement of an endocardial progenitor cell toward the midline to form the heart field. Cardiac muscle progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into endocardial cells of the heart. GO:0003265 regulation of primary heart field cardioblast proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003265 regulation of FHF cardioblast proliferation|regulation of first heart field cardioblast proliferation|regulation of first heart field cardiac proliferation Any process that modulates the frequency, rate or extent of cardioblast proliferation in the primary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. In mammals the primary heart field gives rise to the left ventricle. GO:0003264 regulation of cardioblast proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003264 Any process that modulates the frequency, rate or extent of cardioblast proliferation. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003261 myocardial progenitor cell midline convergence The orderly movement of a myocardial progenitor cell toward the midline to form the heart field. Cardiac muscle progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into myocardial cells of the heart. GO:0003260 cardioblast migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003260 The orderly movement of a cardiac progenitor cell to form the heart field. Cardiac progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into cells of the heart. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. CHEBI:136557 (4aS,10bR)-noroxomaritidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136557 GO:0003238 conus arteriosus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003238 The progression of the conus arteriosus over time, from its formation to the mature structure. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk. GO:0003237 sinus venosus formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003237 The developmental process pertaining to the initial formation of the sinus venosus from unspecified parts. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart. GO:0003239 conus arteriosus morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003239 The process in which the conus arteriosus is generated and organized. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk. GO:0003234 bulbus arteriosus formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003234 The developmental process pertaining to the initial formation of the bulbus arteriosus from unspecified parts. The bulbus arteriosus is an elastic chamber of the heart. GO:0003233 bulbus arteriosus morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003233 The process in which the bulbus arteriosus is generated and organized. The bulbus arteriosus is an elastic cardiac chamber. GO:0003236 sinus venosus morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003236 The process in which the sinus venosus is generated and organized. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart. GO:0003235 sinus venosus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003235 The progression of the sinus venosus over time, from its formation to the mature structure. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart. GO:0003230 cardiac atrium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003230 The process whose specific outcome is the progression of a cardiac atrium over time, from its formation to the mature structure. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle. GO:0003232 bulbus arteriosus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003232 The process whose specific outcome is the progression of the bulbus arteriosus over time, from its formation to the mature structure. The bulbus arteriosus is an elastic heart chamber. GO:0003231 cardiac ventricle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003231 The process whose specific outcome is the progression of a cardiac ventricle over time, from its formation to the mature structure. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart. CHEBI:136524 13-HETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136524 CHEBI:136523 7-HETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136523 CHEBI:136522 (9Z,12Z)-11-hydroxyoctadecadienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136522 CHEBI:136521 roseoflavin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136521 CHEBI:68946 alpha-dimorphecolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68946 CHEBI:68947 13-oxo-9Z,11E-ODE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68947 CHEBI:136520 8-demethyl-8-(methylamino)riboflavin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136520 GO:0003249 cell proliferation involved in heart valve morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003249 The multiplication or reproduction of cells that contributes to the shaping of a heart valve. GO:0003248 heart capillary growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003248 The increase in heart capillaries that accompanies physiological hypertrophy of cardiac muscle. GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003245 The developmental growth of cardiac muscle tissue that contributes to the shaping of the heart. GO:0003244 radial growth involved in right ventricle morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003244 The morphogenic growth in which the right ventricle grows along a radial axis. GO:0003247 post-embryonic cardiac muscle cell growth involved in heart morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003247 The growth of a cardiac muscle cell during the postembryonic period that contributes to the shaping of the heart. GO:0003246 embryonic cardiac muscle cell growth involved in heart morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003246 embryonic cardiac muscle physiological hypertrophy The growth of a cardiac muscle cell during the embryonic period, that contributes to the shaping of the heart. GO:0003241 growth involved in heart morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003241 Developmental growth that contributes to the shaping of the heart. GO:0003240 conus arteriosus formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003240 The developmental process pertaining to the initial formation of the conus arteriosus from unspecified parts. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk. GO:0003243 circumferential growth involved in left ventricle morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003243 The morphogenetic growth in which the left ventricle grows expanding its external boundary. GO:0003242 cardiac chamber ballooning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003242 The morphogenic growth in which the chambers of the heart expand in size, contributing to their shaping. CHEBI:136531 13-oxo-9,11-octadecadienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136531 GO:0003216 cardiac left atrium formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003216 The developmental process pertaining to the initial formation of a left cardiac atrium from unspecified parts. GO:0003215 cardiac right ventricle morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003215 The process in which the right cardiac ventricle is generated and organized. GO:0003218 cardiac left ventricle formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003218 The developmental process pertaining to the initial formation of a left cardiac ventricle from unspecified parts. GO:0003217 cardiac right atrium formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003217 The developmental process pertaining to the initial formation of a cardiac right atrium from unspecified parts. GO:0003212 cardiac left atrium morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003212 The process in which the left cardiac atrium is generated and organized. GO:0003211 cardiac ventricle formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003211 The developmental process pertaining to the initial formation of a cardiac ventricle from unspecified parts. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart. GO:0003214 cardiac left ventricle morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003214 The process in which the left cardiac ventricle is generated and organized. GO:0003213 cardiac right atrium morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003213 The process in which the right cardiac atrium is generated and organized. CHEBI:136509 biliverdin beta(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136509 GO:0003210 cardiac atrium formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003210 The developmental process pertaining to the initial formation of a cardiac atrium from unspecified parts. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle. CHEBI:136508 mycobilin b(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136508 CHEBI:136507 mycobilin a(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136507 CHEBI:29396 disulfide(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29396 CHEBI:136505 homocysteine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136505 GO:0003219 cardiac right ventricle formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003219 The developmental process pertaining to the initial formation of a right cardiac ventricle from unspecified parts. GO:0003227 right ventricular trabecular myocardium morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003227 The process in which the anatomical structures of the right ventricular myocardium are generated and organized. GO:0003226 right ventricular compact myocardium morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003226 The process in which the anatomical structures of the right ventricular compact myocardium are generated and organized. GO:0003229 ventricular cardiac muscle tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003229 ventricular myocardium development The process whose specific outcome is the progression of ventricular cardiac muscle over time, from its formation to the mature structure. GO:0003228 atrial cardiac muscle tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003228 atrial myocardium development The process whose specific outcome is the progression of cardiac muscle of the atrium over time, from its formation to the mature structure. GO:0003223 ventricular compact myocardium morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003223 The process in which the anatomical structures of the compact cardiac ventricle muscle are generated and organized. GO:0003222 ventricular trabecula myocardium morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003222 trabecula carnea morphogenesis The process in which the anatomical structures of the trabecular cardiac ventricle muscle are generated and organized. GO:0003225 left ventricular trabecular myocardium morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003225 The process in which the anatomical structures of cardiac left ventricular trabecular myocardium are generated and organized. GO:0003224 left ventricular compact myocardium morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003224 The process in which the anatomical structures of cardiac left ventricular compact myocardium are generated and organized. GO:0003221 right ventricular cardiac muscle tissue morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003221 right ventricle myocardium morphogenesis The process in which the anatomical structures of the right cardiac ventricle muscle are generated and organized. CHEBI:136518 8-amino-8-demethylriboflavin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136518 GO:0003220 left ventricular cardiac muscle tissue morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003220 left ventricular myocardium morphogenesis The process in which the anatomical structures of left cardiac ventricle muscle are generated and organized. CHEBI:136513 7,7-dihydroxybacteriochlorophyllide c(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136513 CHEBI:136512 bacteriochlorophyllide e(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136512 CHEBI:136511 manganese dioxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136511 CHEBI:136510 biliverdin delta(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136510 CHEBI:136517 anaerobilin dizwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136517 CHEBI:136516 gramine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136516 CHEBI:136515 3-(methylaminomethyl)indole(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136515 CHEBI:136514 indol-3-ylmethylamine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136514 CHEBI:30395 acetylacetonate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30395 CL:1000692 kidney interstitial fibroblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000692 CHEBI:8934 (4-bromophenylsulfanyl)pyruvic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_8934 CHEBI:8944 S-adenosyl-4-methylthio-2-oxobutanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_8944 CHEBI:136589 N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136589 CHEBI:136588 beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136588 CHEBI:136587 (4Z,7Z,11Z,13Z,15E,17S,19Z)-10,17-bis(hydroperoxy)docosahexaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136587 CHEBI:136582 17beta-estradiol 3-sulfate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136582 CHEBI:136581 2-hydroxy-(indol-3-yl)acetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136581 CHEBI:136584 (4Z,7Z,10Z,13Z,16Z)-20-hydroxydocosapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136584 CHEBI:136583 (7Z,13Z,16Z,19Z)-10,11-epoxydocosatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136583 CHEBI:136599 3-amino-D-alanine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136599 CHEBI:136598 3-amino-D-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136598 CHEBI:136593 (R)-2-hydroxy-3-oxo-4-(phosphonatooxy)butanoate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136593 CHEBI:136592 (S)-2-hydroxy-3-oxo-4-(phosphonatooxy)butanoate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136592 CHEBI:136591 D-erythronate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136591 CHEBI:136590 4-O-phosphonato-D-threonate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136590 CHEBI:136597 12-oxo-6-trans-leukotriene B4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136597 CHEBI:136596 4-hydroxy monocarboxylic acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136596 CHEBI:136595 (7Z,11Z,13Z,15E,19Z)-10,17-bis(hydroperoxy)docosapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136595 CHEBI:8984 sodium dodecyl sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_8984 CHEBI:136594 (4Z,7Z,11Z,13Z,15E,17S)-10,17-bis(hydroperoxy)docosapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136594 GO:0052326 obsolete interaction with symbiont via protein secreted by type IV secretion system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052326 interaction with symbiont via protein secreted by type IV secretion system OBSOLETE. An interaction with the symbiont organism mediated by a substance secreted by the other organism by a type IV secretion system. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052325 cell wall pectin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052325 cell wall pectin biosynthesis|pectin biosynthesis during cell wall organization and biogenesis The chemical reactions and pathways resulting in the formation of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues, as part of the organization and biogenesis of the cell wall. GO:0052324 plant-type cell wall cellulose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052324 cellulose biosynthesis during cell wall biosynthesis|cell wall cellulose biosynthesis The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, as part of the organization and biogenesis of the cell wall. GO:0052323 negative regulation of phytoalexin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052323 down-regulation of phytoalexin biosynthesis|negative regulation of phytoalexin biosynthesis|downregulation of phytoalexin biosynthesis|down regulation of phytoalexin biosynthesis|inhibition of phytoalexin biosynthesis Any process that stops, prevents, or reduces the frequency, rate or extent of phytoalexin biosynthesis, the chemical reactions and pathways resulting in the formation of phytoalexins. CHEBI:20960 galactose phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20960 GO:0052329 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052329 GO:0052328 obsolete interaction with symbiont via protein secreted by type III secretion system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052328 interaction with symbiont via protein secreted by type III secretion system OBSOLETE. An interaction with the symbiont organism mediated by a substance secreted by the other organism by a type III secretion system. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052327 obsolete interaction with symbiont via protein secreted by type II secretion system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052327 interaction with symbiont via protein secreted by type II secretion system OBSOLETE. An interaction with the symbiont organism mediated by a substance secreted by the other organism by a type II secretion system. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:20961 D-galactoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20961 CL:1000618 juxtaglomerular complex cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000618 juxtaglomerulus cell CL:1000617 kidney inner medulla cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000617 CL:1000616 kidney outer medulla cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000616 CL:1000615 kidney cortex tubule cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000615 CL:1000612 kidney corpuscule cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000612 CHEBI:78260 1-stearoyl-2-oleoyl-sn-glycero-3-phosphoserine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78260 UBERON:0007376 outer epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007376 hypoderm|epidermis|outer epithelial layer|outer epidermal layer|hypodermis|epidermis (sensu Metazoa) The epidermis is the entire outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species[GO]. UBERON:0007375 roof of mouth biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007375 roof of oral cavity|palatum|primary or secondary palate|roof of buccal cavity|palate A multi-tissue structure consisting of bone and soft tissue that forms a part of the roof of the oral cavity. In mammals this is the combination of the primary palate (premaxilla) and the secondary palate. In early tetrapods it consists of the vomer, pterygoid, parasphenoid, palatine and ectopterygoid bones. CHEBI:78264 1-(1Z-octadecenyl)-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoserine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78264 UBERON:0007373 inferior surface of tongue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007373 ventral surface of tongue|ventrum linguae The lower (inferior) side of the tongue. CHEBI:78263 1-(1Z-octadecenyl)-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78263 CHEBI:78262 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoserine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78262 UBERON:0007371 superior surface of tongue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007371 dorsal surface of tongue The upper (superior) side of the tongue. CHEBI:78261 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78261 CHEBI:78268 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78268 CHEBI:78267 3-deoxy-D-threo-hex-2-ulosarate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78267 CHEBI:78266 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78266 CHEBI:78265 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoserine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78265 GO:0052322 positive regulation of phytoalexin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052322 activation of phytoalexin biosynthesis|up-regulation of phytoalexin biosynthesis|positive regulation of phytoalexin biosynthesis|up regulation of phytoalexin biosynthesis|upregulation of phytoalexin biosynthesis|stimulation of phytoalexin biosynthesis Any process that activates, maintains or increases the frequency, rate or extent of phytoalexin biosynthesis, the chemical reactions and pathways resulting in the formation of phytoalexins. CHEBI:19960 3-amino-3-(4-hydroxyphenyl)propanoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19960 GO:0052321 negative regulation of phytoalexin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052321 down-regulation of phytoalexin metabolism|negative regulation of phytoalexin metabolism|downregulation of phytoalexin metabolism|down regulation of phytoalexin metabolism|inhibition of phytoalexin metabolism Any process that stops, prevents, or reduces the frequency, rate or extent of phytoalexin metabolism, the chemical reactions and pathways involving phytoalexins. GO:0052320 positive regulation of phytoalexin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052320 stimulation of phytoalexin metabolism|up-regulation of phytoalexin metabolism|activation of phytoalexin metabolism|up regulation of phytoalexin metabolism|positive regulation of phytoalexin metabolism|upregulation of phytoalexin metabolism Any process that activates, maintains or increases the frequency, rate or extent of phytoalexin metabolism, the chemical reactions and pathways involving phytoalexins. CHEBI:78269 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphoserine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78269 UBERON:0007379 shelled egg biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007379 egg The hard-shelled reproductive body produced by a bird and especially by the common domestic chicken; also: its contents used as food. GO:0052337 modification by host of symbiont membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052337 modification by host of symbiont cell membrane The process in which an organism effects a change in the structure or function of a symbiont cellular membrane. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052336 modification by host of symbiont cell wall biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052336 metabolism of symbiont cell wall by organism The process in which an organism effects a change in the structure or function of the symbiont cell wall. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052335 modification by host of symbiont cytoskeleton biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052335 The process in which an organism effects a change in the structure or function of the symbiont cytoskeleton. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052334 modification by organism of cytoskeleton of other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052334 modification by organism of cytoskeleton of other organism during symbiotic interaction The process in which an organism effects a change in the structure or function of the cytoskeleton of a second organism, where the two organisms are in a symbiotic interaction. CHEBI:20971 D-galactosyl-N-acetyl-D-glucosaminyl-(1->3)-D-galactosyl-(1->4)-D-glucosylceramide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20971 GO:0052339 disruption by organism of cell wall of other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052339 disassembly by organism of cell wall of other organism during symbiotic interaction The chemical reactions and pathways performed by an organism resulting in the breakdown of the cell wall of a second organism, where the two organisms are in a symbiotic interaction. GO:0052338 disruption by host of symbiont cell wall biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052338 catabolism of symbiont cell wall by organism|disassembly by host of symbiont cell wall|degradation of symbiont cell wall by organism The chemical reactions and pathways performed by an organism resulting in the breakdown of the symbiont cell wall. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CL:1000606 kidney nerve cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000606 PR:000002094 C-C motif chemokine 5 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000002094 TCP228|EoCP|D17S136E|T cell-specific protein P228|small inducible cytokine A5|eosinophil chemotactic cytokine|CCL5|SIS-delta|small-inducible cytokine A5|RANTES|T-cell-specific protein RANTES|SCYA5 A C/C-C motif small inducible chemokine that is a translation product of the human CCL5 gene or a 1:1 ortholog thereof. CL:1000601 ureteral cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000601 UBERON:0007367 surface of tongue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007367 tongue surface An anatomical surface that is part of a tongue. CHEBI:78270 2-oleoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78270 CHEBI:78275 N(5)-hydroxy-L-ornithine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78275 CHEBI:78274 ferruginol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78274 CHEBI:78273 9-cis-retinal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78273 CHEBI:78272 9-cis-retinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78272 CHEBI:78279 lysophosphatidate 18:1 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78279 CHEBI:78278 omega-hydroxymenaquinone-4 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78278 CHEBI:78277 menatetrenone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78277 CHEBI:78276 omega-hydroxyphylloquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78276 CHEBI:19950 3-O-methylgallate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_19950 GO:0052333 modification by organism of cell wall of other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052333 metabolism by organism of cell wall of other organism|modification by organism of cell wall of other organism during symbiotic interaction The process in which an organism effects a change in the structure or function of the cell wall of a second organism, where the two organisms are in a symbiotic interaction. GO:0052332 modification by organism of membrane in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052332 modification by organism of cell membrane in other organism during symbiotic interaction|modification by organism of cell membrane in other organism involved in symbiotic interaction The process in which an organism effects a change in the structure or function of a cellular membrane of a second organism, where the two organisms are in a symbiotic interaction. GO:0052331 hemolysis in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052331 hemolysis of cells in other organism involved in symbiotic interaction|hemolysin activity|haemolysis in other organism involved in symbiotic interaction|hemolysis of cells in other organism during symbiotic interaction|hemolysis by organism of RBCs in other organism during symbiotic interaction|hemolysis by organism of erythrocytes in other organism during symbiotic interaction|hemolysis by organism of red blood cells in other organism during symbiotic interaction The cytolytic destruction of red blood cells, with the release of intracellular hemoglobin, in one organism by another, where two organisms are in a symbiotic interaction. GO:0052330 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052330 GO:0052348 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052348 GO:0052347 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052347 GO:0052346 obsolete positive regulation by organism of defense-related symbiont nitric oxide production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052346 positive regulation by organism of defense-related symbiont nitric oxide production|positive regulation by organism of defense-related symbiont NO production OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the production of nitric oxide as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052345 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052345 GO:0052349 obsolete positive regulation by organism of defense-related symbiont reactive oxygen species production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052349 positive regulation by organism of defense-related symbiont metabolic burst|positive regulation by organism of defense-related symbiont ROI production|positive regulation by organism of defense-related symbiont respiratory burst|positive regulation by organism of defense-related symbiont ROS production|positive regulation by organism of defense-related symbiont active oxygen species production|positive regulation by organism of defense-related symbiont reactive oxygen intermediate production|positive regulation by organism of defense-related symbiont reactive oxidative species production|positive regulation by organism of defense-related symbiont oxidative burst|positive regulation by organism of defense-related symbiont reactive oxygen species production|positive regulation by organism of defense-related symbiont AOS production OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the production of reactive oxygen species as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:78282 2-hydroxy-7-methoxy-5-methyl-1-naphthoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78282 CHEBI:78281 2,7-dihydroxy-5-methyl-1-naphthoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78281 CHEBI:78286 8-demethyl-8-(2,3-O-dimethyl-alpha-L-rhamnosyl)tetracenomycin C biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78286 CHEBI:78285 8-demethyl-8-(2-O-methyl-alpha-L-rhamnosyl)tetracenomycin C biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78285 CHEBI:78283 8-demethyl-8-(alpha-L-rhamnosyl)tetracenomycin C biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78283 GO:0052340 catabolism by organism of cell wall cellulose in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052340 catabolism by organism of cell wall cellulose in other organism during symbiotic interaction The chemical reactions and pathways performed by an organism resulting in the breakdown of cellulose in the cell wall of a second organism, where the two organisms are in a symbiotic interaction. CHEBI:78287 8-demethyl-8-(2,3,4-O-trimethyl-alpha-L-rhamnosyl)tetracenomycin C biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78287 GO:0052344 positive regulation by symbiont of host phytoalexin production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052344 up regulation by symbiont of host phytoalexin production|activation by symbiont of host phytoalexin production|stimulation by symbiont of host phytoalexin production|positive regulation by organism of phytoalexin production in other organism involved in symbiotic interaction|up-regulation by symbiont of host phytoalexin production|upregulation by symbiont of host phytoalexin production Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of the production of phytoalexins as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:19982 3-chloroacrylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19982 GO:0052343 obsolete positive regulation by organism of symbiont phytoalexin production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052343 positive regulation by organism of symbiont phytoalexin production OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the production of phytoalexins as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052342 catabolism by organism of cell wall chitin in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052342 catabolism by organism of cell wall chitin in other organism during symbiotic interaction The chemical reactions and pathways performed by an organism resulting in the breakdown of chitin in the cell wall of a second organism, where the two organisms are in a symbiotic interaction. GO:0052341 catabolism by organism of cell wall pectin in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052341 catabolism by organism of cell wall pectin in other organism during symbiotic interaction The chemical reactions and pathways performed by an organism resulting in the breakdown of pectin in the cell wall of a second organism, where the two organisms are in a symbiotic interaction. GO:0052359 catabolism by organism of glucan in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052359 catabolism by organism of glucan in other organism during symbiotic interaction The chemical reactions and pathways performed by an organism resulting in the breakdown of glucan molecules within a second organism, where the two organisms are in a symbiotic interaction. GO:0052358 catabolism by host of symbiont glucan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052358 The chemical reactions and pathways performed by an organism resulting in the breakdown of glucan molecules within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052357 catabolism by host of symbiont cell wall pectin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052357 The chemical reactions and pathways performed by an organism resulting in the breakdown of pectin in the symbiont cell wall. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052356 catabolism by host of symbiont cell wall chitin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052356 The chemical reactions and pathways performed by an organism resulting in the breakdown of chitin in the symbiont cell wall. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:78293 ophiobolin F biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78293 PR:000002065 mast/stem cell growth factor receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000002065 SCFR|KIT|CD117|Sl|tyrosine-protein kinase Kit|proto-oncogene c-Kit A CSF-1/PDGF receptor-type tyrosine-protein kinase that is a translation product of the human KIT gene or a 1:1 ortholog thereof. CHEBI:78290 L-m-tyrosine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78290 CHEBI:78297 (3S)-3-ammonio-3-(3-chloro-4-hydroxyphenyl)propanoyl residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78297 CHEBI:78296 (3S)-3-ammonio-3-(3-chloro-4,5-dihydroxyphenyl)propanoyl residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78296 CHEBI:78295 food component biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78295 CHEBI:78294 (3R)-3-hydroxy-L-argininium residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78294 GO:0052351 obsolete induction by organism of systemic acquired resistance in symbiont biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052351 induction by organism of systemic acquired resistance in symbiont|activation by organism of systemic acquired resistance in symbiont|activation by organism of SAR in symbiont|induction by organism of SAR in symbiont OBSOLETE. Any process in which an organism activates systemic acquired resistance in the symbiont organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052350 obsolete induction by organism of induced systemic resistance in symbiont biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052350 induction by organism of induced systemic resistance in symbiont|activation by organism of ISR in symbiont|induction by organism of ISR in symbiont|activation by organism of induced systemic resistance in symbiont OBSOLETE. Any process in which an organism activates induced systemic resistance in the symbiont; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:78299 environmental food contaminant biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78299 CHEBI:20954 D-galactosaminide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20954 CHEBI:78298 environmental contaminant biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78298 GO:0052355 catabolism by host of symbiont cell wall cellulose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052355 The chemical reactions and pathways performed by an organism resulting in the breakdown of cellulose in the symbiont cell wall. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052354 catabolism by organism of carbohydrate in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052354 catabolism by organism of carbohydrate in other organism during symbiotic interaction The chemical reactions and pathways performed by an organism resulting in the breakdown of carbohydrate molecules within a second organism, where the two organisms are in a symbiotic interaction. GO:0052353 catabolism by host of symbiont carbohydrate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052353 The chemical reactions and pathways performed by an organism resulting in the breakdown of carbohydrate molecules within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052352 obsolete biosynthesis by host of substance in symbiont biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052352 OBSOLETE. The chemical reactions and pathways performed by an organism in its symbiont resulting in the formation of substances. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052369 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052369 GO:0052368 disruption by organism of cellular component in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052368 catabolism of cellular component in other organism|catabolism of structural constituent in other organism|disassembly by organism of cellular component in other organism involved in symbiotic interaction|disassembly by organism of cellular component in other organism during symbiotic interaction|degradation of cellular component in other organism The chemical reactions and pathways performed by an organism resulting in the breakdown of cellular components of a second organism, where the two organisms are in a symbiotic interaction. GO:0052367 disruption by host of symbiont cellular component biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052367 disassembly by host of symbiont cellular component|degradation of symbiont cellular component by organism|catabolism of symbiont cellular component by organism|catabolism of symbiont structural constituent by organism The chemical reactions and pathways performed by an organism resulting in the breakdown of cellular components of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:19929 3-hydroxy-3-phenylpropionic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19929 GO:0052362 catabolism by host of symbiont protein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052362 The chemical reactions and pathways performed by an organism resulting in the breakdown of protein macromolecules within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052361 catabolism by organism of macromolecule in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052361 catabolism by organism of macromolecule in other organism during symbiotic interaction The chemical reactions and pathways performed by an organism resulting in the breakdown of macromolecules within a second organism, where the two organisms are in a symbiotic interaction. GO:0052360 catabolism by host of symbiont macromolecule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052360 The chemical reactions and pathways performed by an organism resulting in the breakdown of macromolecules within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052366 catabolism by organism of xylan in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052366 catabolism by organism of xylan in other organism during symbiotic interaction The chemical reactions and pathways performed by an organism resulting in the breakdown of xylan within a second organism, where the two organisms are in a symbiotic interaction. GO:0052365 catabolism by host of symbiont xylan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052365 The chemical reactions and pathways performed by an organism resulting in the breakdown of xylan within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052364 catabolism by host of substance in symbiont biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052364 The chemical reactions and pathways performed by an organism in its symbiont resulting in the breakdown of substances. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052363 catabolism by organism of protein in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052363 catabolism by organism of protein in other organism during symbiotic interaction The chemical reactions and pathways performed by an organism resulting in the breakdown of protein macromolecules within the second organism, where the two organisms are in a symbiotic interaction. GO:0052379 obsolete modulation by organism of entry into other organism via phagocytosis involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052379 modulation by organism of entry into other organism via phagocytosis during symbiotic interaction|modulation by organism of entry into other organism via other organism phagocytosis during symbiotic interaction OBSOLETE. Any process in which an organism modulates the frequency, rate or extent to which it enters into a second organism via the phagocytotic processes of the other organism, where the two organisms are in a symbiotic interaction. GO:0052378 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052378 GO:0052373 suppression of symbiont entry into host by host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052373 downregulation by organism of entry into other organism during symbiotic interaction|inhibition by organism of entry into other organism during symbiotic interaction|down regulation by organism of entry into other organism during symbiotic interaction|negative regulation by organism of entry into other organism involved in symbiotic interaction|negative regulation by organism of entry into other organism during symbiotic interaction|down-regulation by organism of entry into other organism during symbiotic interaction Any process in which an organism stops, prevents, or reduces the frequency, rate or extent to which it enters into a second organism, where the two organisms are in a symbiotic interaction. GO:0052372 modulation by symbiont of entry into host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052372 regulation by organism of entry into other organism during symbiotic interaction|modulation by organism of entry into other organism during symbiotic interaction|modulation by symbiont of entry into host|regulation by organism of entry into other organism involved in symbiotic interaction Any process in which an organism modulates the frequency, rate or extent to which it enters into the host organism, where the two organisms are in a symbiotic interaction. GO:0052371 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052371 GO:0052370 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052370 GO:0052377 obsolete evasion or tolerance by organism of symbiont-produced phytoalexins biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052377 evasion or tolerance by organism of symbiont-produced phytoalexins|symbiont phytoalexin detoxification|evasion or tolerance of phytoalexins produced by symbiont in response to organism|evasion or tolerance by organism of symbiont phytoalexins OBSOLETE. The process by which an organism avoids the effects of phytoalexins produced as a defense response by the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052376 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052376 GO:0052375 obsolete evasion or tolerance by organism of symbiont-produced nitric oxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052375 evasion or tolerance by organism of symbiont-produced nitric oxide|evasion or tolerance of NO produced by symbiont in response to organism|evasion or tolerance by organism of symbiont NO|evasion or tolerance by organism of symbiont-produced NO|evasion or tolerance of nitric oxide produced by symbiont in response to organism|evasion or tolerance by organism of symbiont nitric oxide OBSOLETE. The process by which an organism avoids the effects of nitric oxide produced as a defense response by the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:20937 D-fructuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20937 GO:0052374 obsolete negative regulation by symbiont of entry into host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052374 down regulation by symbiont of entry into host|downregulation by symbiont of entry into host|down-regulation by symbiont of entry into host|inhibition by symbiont of entry into host OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent to which it enters into the host organism, where the two organisms are in a symbiotic interaction. GO:0052389 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052389 UBERON:0007391 pelvic appendage cartilage tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007391 pelvic fin cartilage A cartilage tissue that is part of a pelvic appendage. UBERON:0007390 pectoral appendage cartilage tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007390 pectoral fin cartilage A cartilage tissue that is part of a pectoral appendage. GO:0052380 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052380 CHEBI:19946 xylosylglycoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19946 GO:0052384 obsolete evasion or tolerance by organism of symbiont-produced reactive oxygen species biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052384 evasion or tolerance of defense-related symbiont respiratory burst|evasion or tolerance of defense-related symbiont oxidative burst|evasion or tolerance by organism of symbiont-produced reactive oxygen species|evasion or tolerance of symbiont-produced AOS|evasion or tolerance of reactive oxygen species produced by symbiont in response to organism|evasion or tolerance of symbiont-produced reactive oxygen intermediates|evasion by organism of cellular damage caused by symbiont oxidative burst|evasion or tolerance of defense-related symbiont metabolic burst|evasion or tolerance of symbiont-produced ROIs|evasion or tolerance of symbiont-produced active oxygen species|evasion or tolerance of symbiont-produced ROS|evasion or tolerance by organism of reactive oxygen species produced during symbiont defense response OBSOLETE. The process by which an organism avoids the effects of reactive oxygen species produced as a defense response by the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052383 obsolete induction by organism of symbiont innate immunity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052383 activation by organism of symbiont innate immune response|activation by organism of symbiont innate immunity|induction by organism of symbiont innate immune response|induction by organism of symbiont innate immunity OBSOLETE. The activation by an organism of the innate immune response of the symbiont organism; the innate immune response is the symbiont's first line of defense against infection. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052382 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052382 GO:0052381 tRNA dimethylallyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052381 RHEA:26482|MetaCyc:RXN0-6274|EC:2.5.1.75|Reactome:R-HSA-6787567|Reactome:R-HSA-6784462 tRNA isopentenyltransferase activity|tRNA prenyltransferase activity|dimethylallyl-diphosphate:tRNA dimethylallyltransferase activity Catalysis of the reaction: dimethylallyl diphosphate + tRNA = diphosphate + tRNA containing 6-dimethylallyladenosine. GO:0052388 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052388 CHEBI:20902 allose phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20902 GO:0052387 obsolete induction by organism of symbiont apoptosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052387 induction by organism of symbiont apoptosis|induction by organism of symbiont apoptotic programmed cell death|activation by organism of symbiont apoptosis|activation by organism of symbiont apoptotic programmed cell death OBSOLETE. Any process by which an organism activates programmed cell death in the symbiont, where programmed cell death proceeds by apoptosis. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052386 cell wall thickening biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052386 A type of cell wall modification in which the cell wall is reinforced and made thicker. GO:0052385 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052385 UBERON:0007389 paired limb/fin cartilage biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007389 A cartilage tissue that is part of a paired limb or fin. UBERON:0007386 pelvic appendage lymph vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007386 A lymphatic vessel that is part of a pelvic appendage. GO:0052391 induction by symbiont of defense-related host calcium ion flux biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052391 activation by organism of host Ca2+ flux|stimulation by symbiont of defense-related host calcium ion flux|activation by organism of host calcium ion flux|up-regulation by symbiont of defense-related host calcium ion flux|positive regulation by organism of defense-related host Ca2+ flux|induction by organism of defense-related calcium ion flux in other organism involved in symbiotic interaction|upregulation by symbiont of defense-related host calcium ion flux|induction by organism of host Ca2+ flux|up regulation by symbiont of defense-related host calcium ion flux|positive regulation by symbiont of defense-related host calcium ion flux|activation by symbiont of defense-related host calcium ion flux|positive regulation by organism of defense-related calcium ion flux in other organism involved in symbiotic interaction The activation by an organism of a flux of calcium ions that occurs as part of the defense response of a host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. UBERON:0007385 pectoral appendage lymph vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007385 A lymphatic vessel that is part of a pectoral appendage. GO:0052390 induction by symbiont of host innate immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052390 induction of host innate immunity|induction by organism of host innate immune response|positive regulation of innate immune response in other organism|positive regulation by symbiont of host innate immune response|positive regulation by symbiont of host innate immunity|up regulation by symbiont of host innate immunity|upregulation by symbiont of host innate immunity|induction by symbiont of host innate immunity|activation by organism of host innate immunity|activation by organism of host innate immune response|positive regulation of host innate immune response|induction by organism of innate immune response in other organism involved in symbiotic interaction|up-regulation by symbiont of host innate immunity|activation by symbiont of host innate immunity|stimulation by symbiont of host innate immunity The activation by a symbiont of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction. UBERON:0007384 appendage lymph vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007384 A lymphatic vessel that is part of a limb/fin. UBERON:0007383 enveloping layer of ectoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007383 enveloping layer|EVL Outermost layer of cells surrounding the embryo. GO:0052395 obsolete induction by organism of defense-related symbiont nitric oxide production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052395 induction by organism of defense-related symbiont nitric oxide production|activation by organism of defense-related symbiont nitric acid production|induction by organism of defense-related symbiont NO production|activation by organism of defense-related symbiont NO production OBSOLETE. The activation by an organism of the production of nitric oxide as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052394 obsolete induction by organism of defense-related symbiont cell wall thickening biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052394 activation by organism of symbiont defense-related cell wall thickening|induction by organism of symbiont defensive cell wall thickening|induction by organism of defense-related symbiont cell wall thickening|activation by organism of symbiont defensive cell wall thickening OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of symbiont processes resulting in the thickening of its cell walls, occurring as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052393 obsolete induction by host of symbiont defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052393 activation of symbiont defense response OBSOLETE. The activation by an organism of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052392 obsolete induction by organism of defense-related symbiont calcium ion flux biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052392 activation by organism of symbiont calcium ion flux|activation by organism of symbiont Ca2+ flux|induction by organism of defense-related symbiont calcium ion flux|induction by organism of symbiont Ca2+ flux OBSOLETE. The activation by an organism of a flux of calcium ions that occurs as part of the defense response of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052399 obsolete induction by organism of symbiont programmed cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052399 induction by organism of symbiont programmed cell death|activation by organism of symbiont programmed cell death OBSOLETE. The activation by an organism of programmed cell death in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052398 obsolete induction by organism of symbiont phytoalexin production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052398 activation by organism of symbiont phytoalexin production|induction by organism of symbiont phytoalexin production OBSOLETE. The activation by an organism of the production of phytoalexins as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:20912 D-arabinonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20912 GO:0052397 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052397 GO:0052396 obsolete induction by organism of symbiont non-apoptotic programmed cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052396 activation by organism of symbiont non-apoptotic programmed cell death|induction by organism of symbiont non-apoptotic programmed cell death OBSOLETE. Any process by which an organism activates programmed cell death in the symbiont, where programmed cell death proceeds by a non-apoptotic pathway. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0003315 heart rudiment formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003315 heart cone formation The developmental process pertaining to the initial formation of the heart rudiment. GO:0003314 heart rudiment morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003314 heart cone morphogenesis The process in which the anatomical structures of the heart rudiment are generated and organized. GO:0003317 cardioblast cell midline fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003317 cardiac progenitor cell midline fusion The attachment of cardiac progenitor cells to one another that contributes to the formation of the heart rudiment. GO:0003316 establishment of myocardial progenitor cell apical/basal polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003316 myocardial progenitor epithelial polarization The specification and formation of the apicobasal polarity of an myocardial progenitor cell that contributes to the formation of the heart rudiment. GO:0003311 pancreatic D cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003311 pancreatic delta cell differentiation The process in which relatively unspecialized cells acquire specialized structural and functional features that characterize a pancreatic delta cell. A delta cell is a cell of the pancreas that produces somatostatin. GO:0003310 pancreatic A cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003310 pancreatic alpha cell differentiation The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic A cell. A pancreatic A cell is a cell in the pancreas that secretes glucagon. CHEBI:30249 N-formyl-L-kynurenine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30249 GO:0003313 heart rudiment development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003313 heart cone development The progression of the heart rudiment over time, from its initial formation to the mature structure. The heart rudiment is a cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube. CHEBI:30248 beta-D-Gal-(1->3)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30248 GO:0003312 pancreatic PP cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003312 pancreatic polypeptide-producing cell differentiation The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic polypeptide-producing cell. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide. CHEBI:44898 pheophytin a biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_44898 CHEBI:44897 phosphoenolpyruvic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_44897 CHEBI:29256 thiol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29256 CHEBI:29259 hydrogenphosphite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29259 CHEBI:29258 dihydrogenphosphite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29258 CHEBI:136606 N-arachidonoyl-L-phenylalanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136606 CHEBI:29255 hydrogenborate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29255 CHEBI:29254 dihydrogenborate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29254 GO:0042923 neuropeptide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042923 Interacting selectively and non-covalently and stoichiometrically with neuropeptides, peptides with direct synaptic effects (peptide neurotransmitters) or indirect modulatory effects on the nervous system (peptide neuromodulators). GO:0042922 neuromedin U receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042922 Interacting selectively and non-covalently with one or more specific sites on a neuromedin U receptor. GO:0042925 benzoate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042925 RHEA:32811 benzoate transporter activity Enables the directed movement of benzoate, the anion of benzoic acid (benzenecarboxylic acid) from one side of a membrane to the other. GO:0042924 neuromedin U binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042924 NMU binding Interacting selectively and non-covalently and stoichiometrically with neuromedin U, a hypothalamic peptide involved in energy homeostasis and stress responses. GO:0042921 glucocorticoid receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042921 glucocorticoid receptor signalling pathway Any series of molecular signals generated as a consequence of a glucocorticoid binding to its receptor. GO:0042920 3-hydroxyphenylpropionic acid transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042920 m-hydroxyphenylpropionic acid transport|3-hydroxyphenylpropionic acid transport|3-(3-hydroxyphenyl)propionic acid transport The directed movement of 3-hydroxyphenylpropionic acid across a lipid bilayer, from one side of a membrane to the other. CHEBI:136602 (1->4)-6-phospho-alpha-D-glucan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136602 UBERON:0007418 neural decussation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007418 chiasm|neuraxis chiasm|decussation of neuraxis|neuraxis chiasma|chiasma|decussation|neuraxis decussation Nerve fibers crossing the midline of the neuraxis relative to their point of origin, on a course to from one level of the nervous system to another. (CUMBO, Heimer, L. The Human Brain, 2nd ed., 1995, pg 6) CHEBI:30245 linoleate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30245 UBERON:0007417 peduncle of neuraxis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007417 neuraxis peduncle GO:0042927 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042927 GO:0003319 cardioblast migration to the midline involved in heart rudiment formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003319 The orderly movement of a cardioblast toward the midline that contributes to the initial appearance of the heart rudiment. UBERON:0007415 nucleus of midbrain reticular formation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007415 midbrain reticular nucleus|midbrain reticular formation nucleus|mesencephalic reticular nucleus A nucleus of midbrain tegmentum that is part of a midbrain reticular formation. GO:0042926 3-hydroxyphenylpropionic acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042926 3-(3-hydroxyphenyl)propionic acid transporter activity|3-hydroxyphenylpropionic acid transporter activity|m-hydroxyphenylpropionic acid transporter activity Enables the directed movement of 3-hydroxyphenylpropionic acid from one side of a membrane to the other. GO:0003318 cell migration to the midline involved in heart development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003318 The orderly movement of a cell toward the midline that contributes to the progression of the heart over time. UBERON:0007414 nucleus of midbrain tegmentum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007414 tegmental nuclei|tegmental nucleus A nucleus of brain that spans a midbrain tegmentum. GO:0042929 ferrichrome transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042929 ferrichrome transporter activity Enables the directed movement of a ferrichrome from one side of a membrane to the other. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine. GO:0042928 ferrichrome import into cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042928 ferrichrome transport A process in which ferrichrome is transported into the cell by specific cell surface receptors. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine. GO:0003326 pancreatic A cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003326 The commitment of a cell to a pancreatic A cell and its capacity to differentiate into a pancreatic A cell. A pancreatic A cell is a cell in the pancreas that secretes glucagon. GO:0003325 pancreatic PP cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003325 The process whose specific outcome is the progression of a pancreatic PP cell over time, from its formation to the mature structure. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide. GO:0003328 pancreatic D cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003328 The commitment of a cell to a pancreatic D cell fate and its capacity to differentiate into a pancreatic D cell. A delta cell is a cell of the pancreas that produces somatostatin. GO:0003327 type B pancreatic cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003327 pancreatic B cell fate commitment The commitment of a cell to a type B pancreatic cell fate and its capacity to differentiate into a type B pancreatic cell. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin. GO:0003322 pancreatic A cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003322 pancreatic alpha cell development The process whose specific outcome is the progression of a pancreatic A cell over time, from its formation to the mature structure. A pancreatic A cell is a cell in the pancreas that secretes glucagon. GO:0003321 positive regulation of blood pressure by epinephrine-norepinephrine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003321 Any process in which the force of blood traveling through the circulatory system is increased by the chemicals epinephrine and norepinephrine. GO:0003324 pancreatic D cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003324 pancreatic delta cell development The process whose specific outcome is the progression of a pancreatic delta cell over time, from its formation to the mature structure. A delta cell is a cell of the pancreas that produces somatostatin. GO:0003323 type B pancreatic cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003323 pancreatic B cell development|pancreatic beta cell development The process whose specific outcome is the progression of a type B pancreatic cell over time, from its formation to the mature structure. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin. GO:0003320 heart rudiment involution biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003320 The inward folding of myocardial tissue derived from the right half of the heart rudiment that will form the future ventral part of the heart tube. CHEBI:136618 N-[(9Z)-hexadecenoyl]glycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136618 CHEBI:44884 pentan-1-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_44884 CHEBI:29269 selenophosphoric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29269 CHEBI:29264 tRNA(Sec) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29264 CHEBI:29265 Asn-tRNA(Asn) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29265 GO:0042934 achromobactin transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042934 achromobactin transporter activity Enables the transfer of achromobactin, a citrate siderophore, from one side of a membrane to the other. GO:0042933 chrysobactin transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042933 chrysobactin transporter activity Enables the directed movement of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine) from one side of a membrane to the other. GO:0042936 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042936 GO:0042935 achromobactin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042935 The directed movement of achromobactin, a citrate siderophore, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0042930 enterobactin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042930 enterochelin transport The directed movement of the siderochrome enterobactin, a cyclic trimer of 2, 3 dihydroxybenzoylserine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:136616 N-oleoyl-L-leucine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136616 CHEBI:136615 N-oleoyl-L-glutamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136615 CHEBI:136614 N-oleoyl-L-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136614 GO:0042932 chrysobactin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042932 The directed movement of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0042931 enterobactin transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042931 enterochelin transporter activity|enterobactin transporter activity Enables the directed movement of the siderochrome enterochelin, a cyclic trimer of 2, 3 dihydroxybenzoylserine from one side of a membrane to the other. CHEBI:30256 thiocarbonyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30256 GO:0042938 dipeptide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042938 The directed movement of a dipeptide, a combination of two amino acids by means of a peptide (-CO-NH-) link, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0003329 pancreatic PP cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003329 The commitment of a cell to a pancreatic PP cell fate and its capacity to differentiate into a pancreatic PP cell. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide. GO:0042937 tripeptide transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042937 tripeptide transporter activity Enables the transfer of a tripeptide, a compound containing three amino acids linked together by peptide bonds, from one side of a membrane to the other. GO:0042939 tripeptide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042939 The directed movement of a tripeptide, a compound containing three amino acids linked together by peptide bonds, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:78209 2-arachidonoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78209 CHEBI:78208 azelaate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78208 CHEBI:78207 1-palmitoyl-2-azelaoyl-sn-glycero-3-phosphocholine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78207 GO:0042945 D-serine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042945 D-serine transporter activity|D-serine permease activity Enables the transfer of D-serine from one side of a membrane to the other. D-serine is the D-enantiomer of 2-amino-3-hydroxypropanoic acid. GO:0042944 D-alanine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042944 D-alanine transporter activity Enables the transfer of D-alanine from one side of a membrane to the other. D-alanine is the D-enantiomer of 2-aminopropanoic acid. GO:0042947 glucoside transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042947 Enables the transfer of glucosides from one side of a membrane to the other. Glucosides are glycosides in which the sugar group is a glucose residue. GO:0042946 glucoside transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042946 The directed movement of glucosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucosides are glycosides in which the sugar group is a glucose residue. GO:0042941 D-alanine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042941 The directed movement of D-alanine, the D-enantiomer of 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0042940 D-amino acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042940 The directed movement of the D-enantiomer of an amino acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0042943 D-amino acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042943 D-amino acid transporter activity Enables the transfer of D-amino acids from one side of a membrane to the other. D-amino acids are the D-enantiomers of amino acids. GO:0042942 D-serine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042942 The directed movement of D-serine, the D-enantiomer of 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:78202 1-alkylglycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78202 CHEBI:78201 monoacylglycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78201 CHEBI:78200 2-acylglycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78200 CHEBI:78206 fatty acid ethyl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78206 GO:0042949 arbutin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042949 The directed movement of arbutin, a glycoside found in the bearberry and related plants which has been used to treat urinary-tract diseases, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0042948 salicin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042948 The directed movement of salicin (saligenin-beta-D-glucopyranoside), a glucoside of o-hydroxybenzylalcohol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:78204 monoalkylglycerophosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78204 CHEBI:78203 1-(alk-1-enyl)-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78203 GO:0003304 myocardial epithelial involution involved in heart jogging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003304 The morphogenetic process in which the myocardium bends along a linear axis and contributes to the process of heart jogging. GO:0003303 BMP signaling pathway involved in heart jogging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003303 BMP signalling pathway involved in heart jogging A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the process of heart jogging. CHEBI:616988 mannose 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_616988 GO:0003306 Wnt signaling pathway involved in heart development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003306 Wnt receptor signalling pathway involved in heart development|Wnt receptor signaling pathway involved in heart development|Wnt-activated signaling pathway involved in heart development The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the heart over time. CHEBI:78218 1-(alk-1-enyl)-2-acetyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78218 GO:0003305 cell migration involved in heart jogging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003305 The orderly movement of a cell of the myocardium from one site to another that will contribute to heart jogging. GO:0003300 cardiac muscle hypertrophy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003300 The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. GO:0003302 transforming growth factor beta receptor signaling pathway involved in heart jogging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003302 transforming growth factor beta receptor signalling pathway involved in heart jogging A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to the process of heart jogging. GO:0003301 physiological cardiac muscle hypertrophy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003301 The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. This process contributes to the developmental growth of the heart. GO:0042950 salicin transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042950 Enables the transfer of salicin (saligenin-beta-D-glucopyranoside), a glucoside of o-hydroxybenzylalcohol, from one side of a membrane to the other. CHEBI:29242 arsenite(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29242 CHEBI:29241 silicate(4-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29241 CHEBI:29243 arsenite(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29243 GO:0042956 maltodextrin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042956 The directed movement of maltodextrin, any polysaccharide of glucose residues in beta-(1,4) linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0042955 dextrin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042955 The directed movement of dextrin, any one, or the mixture, of the intermediate polysaccharides formed during the hydrolysis of starch, which are dextrorotatory, soluble in water, and precipitable in alcohol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0042958 maltodextrin transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042958 Enables the transfer of maltodextrin, any polysaccharide of glucose residues in beta-(1,4) linkage, from one side of a membrane to the other. GO:0042957 dextrin transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042957 Enables the transfer of dextrin, any one, or the mixture, of the intermediate polysaccharides formed during the hydrolysis of starch, which are dextrorotatory, soluble in water, and precipitable in alcohol, from one side of a membrane to the other. GO:0042952 beta-ketoadipate pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042952 ortho-cleavage pathway A pathway of aromatic compound degradation by ortho-cleavage; one branch converts protocatechuate, derived from phenolic compounds, to beta-ketoadipate, and the other branch converts catechol, generated from various aromatic hydrocarbons, amino aromatics, and lignin monomers, also to beta-ketoadipate. Two additional steps accomplish the conversion of beta-ketoadipate to tricarboxylic acid cycle intermediates. GO:0042951 arbutin transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042951 Enables the transfer of arbutin, a glycoside found in the bearberry and related plants which has been used to treat urinary-tract diseases, from one side of a membrane to the other. GO:0042954 obsolete lipoprotein transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042954 OBSOLETE. Enables the directed movement of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids, into, out of or within a cell, or between cells. GO:0042953 lipoprotein transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042953 The directed movement of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:78213 1-acylglycero-3-phospho-L-serine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78213 CHEBI:78211 1-acylglycero-3-phospho-1'-glycerol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78211 CHEBI:30232 abieta-7,13-diene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30232 CHEBI:78210 monoacylglycero-3-phosphoglycerol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78210 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003308 negative regulation of Wnt receptor signalling pathway involved in heart development|negative regulation of Wnt receptor signaling pathway involved in heart development|negative regulation of Wnt-activated signaling pathway involved in heart development Any process that decreases the rate, frequency, or extent of the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the heart over time. GO:0042959 alkanesulfonate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042959 alkanesulfonate transporter activity|alkanesulphonate transporter activity Enables the directed movement of alkanesulfonate from one side of a membrane to the other. GO:0003307 regulation of Wnt signaling pathway involved in heart development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003307 regulation of Wnt receptor signaling pathway involved in heart development|regulation of Wnt receptor signalling pathway involved in heart development|regulation of Wnt-activated signaling pathway involved in heart development Any process that modulates the rate, frequency, or extent of the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the heart over time. CHEBI:78216 alpha,beta-didehydrotryptophan zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78216 CHEBI:78215 1-hexanoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78215 GO:0003309 type B pancreatic cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003309 pancreatic beta cell differentiation|pancreatic B cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features of a type B pancreatic cell. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin. CHEBI:78214 2-acylglycero-3-phospho-Lserine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78214 CHEBI:78229 1,2-dioctanoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78229 CHEBI:29216 3-hydroxy-2-methylquinolin-4(1H)-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29216 CHEBI:29219 chlorous acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29219 CHEBI:29213 sulfinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29213 GO:0042961 ATPase-coupled antimonite transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042961 ATP-dependent antimonite transporter activity|antimonite-transporting ATPase activity|antimonite ABC transporter Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + antimonite(in) = ADP + phosphate + antimonite(out). GO:0042960 antimonite secondary active transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042960 antimonite porter activity Enables the transfer of antimonite from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. CHEBI:29214 sulfonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29214 CHEBI:29210 trithionic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29210 GO:0042967 obsolete acyl-carrier-protein biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042967 acyl-carrier-protein synthesis|acyl-carrier protein biosynthesis|acyl-carrier-protein formation|ACP biosynthetic process|ACP biosynthesis|acyl carrier protein biosynthesis|acyl carrier protein biosynthetic process|acyl-carrier-protein biosynthesis|acyl-carrier-protein anabolism OBSOLETE. The chemical reactions and pathways resulting in the formation of acyl-carrier protein. GO:0042966 biotin carboxyl carrier protein biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042966 biotin carboxyl carrier protein synthesis|biotin carboxyl carrier protein formation|BCCP biosynthesis|BCCP biosynthetic process|biotin carboxyl carrier protein biosynthesis|biotin carboxyl carrier protein anabolism The chemical reactions and pathways resulting in the formation of the biotin carboxyl carrier protein, a subunit of acetyl-coenzyme A carboxylase. GO:0042969 obsolete lactone transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042969 OBSOLETE. The directed movement of lactone from one side of a membrane to the other. A lactone is a cyclic ester of a hydroxy carboxylic acid, containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring. GO:0042968 homoserine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042968 The directed movement of homoserine, alpha-amino-gamma-hydroxybutyric acid, an intermediate in the biosynthesis of cystathionine, threonine and methionine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:78220 2-methyl-1-pyrrolinium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78220 GO:0042963 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042963 GO:0042962 acridine:proton antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042962 acridine:hydrogen antiporter activity|acridine efflux pump activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + acridine(in) = H+(in) + acridine(out). GO:0042965 obsolete glutaredoxin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042965 glutaredoxin anabolism|glutaredoxin synthesis|glutaredoxin formation|glutaredoxin biosynthesis OBSOLETE. The chemical reactions and pathways resulting in the formation of a small disulfide-containing redox protein that serves as a glutathione-disulfide oxidoreductase. GO:0042964 obsolete thioredoxin reduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042964 thioredoxin biosynthesis|thioredoxin anabolism|thioredoxin synthesis|thioredoxin formation OBSOLETE. The chemical reactions and pathways resulting in the reduction of thioredoxin, a small disulfide-containing redox protein that serves as a general protein disulfide oxidoreductase. PR:000002038 eotaxin-like cytokine biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000002038 A C/C-C motif small inducible chemokine that is a member of a subfamily that includes eotaxin. CHEBI:78224 1-alkyl-2-acylglycero-3-phosphoserine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78224 CHEBI:78223 1-caproyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78223 CHEBI:78222 (R)-2-methylpyrrolidinium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78222 CHEBI:30200 kaempferol 3-O-beta-D-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30200 CHEBI:78221 monoacylglycero-3-phospho-L-serine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78221 CHEBI:78228 1,2-dioctanoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78228 CHEBI:78227 1,2-dicapryl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78227 CHEBI:78226 1,2-dicapryl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78226 CHEBI:78225 alkyl,acylglycero-3-phospho-L-serine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78225 CHEBI:20891 (R)-4'-phosphopantothenate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20891 CHEBI:29228 hydrogen fluoride biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29228 GO:0042970 homoserine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042970 homoserine transporter activity Enables the transfer of homoserine from one side of a membrane to the other. Homoserine is alpha-amino-gamma-hydroxybutyric acid, an intermediate in the biosynthesis of cystathionine, threonine and methionine. GO:0042972 licheninase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042972 EC:3.2.1.73|MetaCyc:3.2.1.73-RXN beta-(1->3), (1->4)-D-glucan 4-glucanohydrolase activity|1,3;1,4-beta-glucan 4-glucanohydrolase activity|beta-glucanase activity|1,3-1,4-beta-D-glucan 4-glucanohydrolase activity|1,3;1,4-beta-glucan endohydrolase activity|lichenase activity|1,3-1,4-beta-glucan 4-glucanohydrolase activity|endo-beta-1,3-1,4 glucanase activity|mixed linkage beta-glucanase activity Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic linkages in beta-D-glucans containing (1->3) and (1->4) bonds. CHEBI:44841 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_44841 GO:0042971 obsolete lactone transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042971 OBSOLETE. Enables the transfer of lactone from one side of a membrane to the other. A lactone is a cyclic ester of a hydroxy carboxylic acid, containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring. CHEBI:29222 hypochlorite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29222 GO:0042978 ornithine decarboxylase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042978 L-ornithine carboxy-lyase activator activity Upregulation of the activity of the enzyme ornithine decarboxylase. GO:0042977 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042977 GO:0042979 ornithine decarboxylase regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042979 Modulation of the activity of the enzyme ornithine decarboxylase. GO:0042974 retinoic acid receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042974 RAR binding Interacting selectively and non-covalently with the retinoic acid receptor, a ligand-regulated transcription factor belonging to the nuclear receptor superfamily. CHEBI:78231 1,2-diacylglycero-3-phospho-1-inositol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78231 GO:0042973 glucan endo-1,3-beta-D-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042973 MetaCyc:3.2.1.39-RXN|EC:3.2.1.39 1,3-beta-D-glucan 3-glucanohydrolase activity|kitalase activity|oligo-1,3-glucosidase activity|beta-1,3-glucanase|callase activity|1,3-beta-D-glucan glucanohydrolase activity|endo-(1->3)-beta-D-glucanase activity|endo-1,3-beta-glucosidase activity|endo-1,3-beta-D-glucanase|laminaranase activity|endo-(1,3)-beta-D-glucanase activity|laminarinase activity|(1->3)-beta-glucan 3-glucanohydrolase activity|(1->3)-beta-glucan endohydrolase activity|endo-1,3-beta-glucanase activity Catalysis of the hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)-beta-D-glucans. GO:0042976 activation of Janus kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042976 positive regulation of JAK protein activity by tyrosine phosphorylation|tyrosine phosphorylation of JAK protein|tyrosine phosphorylation of JAK1 protein|activation of JAK2 protein|activation of JAK1 protein|activation of JAK2 kinase activity|activation of JAK1 kinase activity|tyrosine phosphorylation of JAK2 protein|activation of JAK protein|activation of JAK protein by tyrosine phosphorylation The process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it. GO:0042975 peroxisome proliferator activated receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042975 PPAR binding Interacting selectively and non-covalently with any of the peroxisome proliferator activated receptors, alpha, beta or gamma. CHEBI:78234 monoacylglycero-3-phospho-1-inositol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78234 CHEBI:30212 photon biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30212 CHEBI:78233 2-acylglycero-3-phospho-1-inositol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78233 CHEBI:78232 1-acylglycero-3-phospho-1-inositol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78232 CHEBI:20899 D-alloisoleucine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20899 CHEBI:78239 3-methyl-L-tyrosine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78239 CHEBI:78237 3-amino-4-hydroxybenzaldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78237 CHEBI:78236 N-acetyl-L-cysteinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78236 GO:0052304 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052304 GO:0052303 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052303 GO:0052302 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052302 GO:0052301 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052301 GO:0052308 obsolete pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052308 pathogen-associated molecular pattern dependent modulation by organism of innate immunity in other organism involved in symbiotic interaction|pathogen-associated molecular pattern dependent modulation by organism of innate immunity in other organism during symbiotic interaction OBSOLETE. Any process that involves recognition of a pathogen-associated molecular pattern, and by which an organism modulates the frequency, rate or extent of the innate immune response, the first line of defense against infection, of a second organism, where the two organisms are in a symbiotic interaction. GO:0052307 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052307 GO:0052306 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052306 GO:0052305 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052305 GO:0042981 regulation of apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042981 apoptosis regulator activity|regulation of apoptosis Any process that modulates the occurrence or rate of cell death by apoptotic process. GO:0042980 obsolete cystic fibrosis transmembrane conductance regulator binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042980 CFTR binding|cystic fibrosis transmembrane conductance regulator binding OBSOLETE. Interacting selectively and non-covalently with the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein. GO:0042983 amyloid precursor protein biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042983 amyloid precursor protein biosynthesis|amyloid precursor protein anabolism|amyloid precursor protein synthesis|amyloid precursor protein formation|APP biosynthesis|APP biosynthetic process The chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease. GO:0042982 amyloid precursor protein metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042982 APP metabolic process|amyloid precursor protein metabolism|APP metabolism The chemical reactions and pathways involving amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease. GO:0052309 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052309 GO:0042989 sequestering of actin monomers biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042989 actin monomer sequestration|sequestration of actin monomers|actin monomer sequestering|actin monomer sequestering activity|actin monomer retention|retention of actin monomers|storage of actin monomers|actin monomer storage The selective interaction of actin monomers with specific molecules that inhibit their polymerization by preventing their access to other monomers. GO:0042988 X11-like protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042988 X11L binding Interacting selectively and non-covalently with X11-like protein, a neuron-specific adaptor protein. GO:0042985 negative regulation of amyloid precursor protein biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042985 down-regulation of amyloid precursor protein biosynthetic process|negative regulation of amyloid precursor protein biosynthesis|negative regulation of amyloid precursor protein anabolism|negative regulation of amyloid precursor protein synthesis|negative regulation of amyloid precursor protein formation|downregulation of amyloid precursor protein biosynthetic process|down regulation of amyloid precursor protein biosynthetic process|inhibition of amyloid precursor protein biosynthetic process|negative regulation of APP biosynthesis|negative regulation of APP biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta. GO:0042984 regulation of amyloid precursor protein biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042984 regulation of amyloid precursor protein formation|regulation of APP biosynthetic process|regulation of APP biosynthesis|regulation of amyloid precursor protein biosynthesis|regulation of amyloid precursor protein anabolism|regulation of amyloid precursor protein synthesis Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta. CHEBI:78241 5-hydroxy-3-methyl-L-tyrosine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78241 GO:0042987 amyloid precursor protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042987 APP catabolic process|APP catabolism|amyloid precursor protein degradation|amyloid precursor protein breakdown|amyloid precursor protein catabolism The chemical reactions and pathways resulting in the breakdown of amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease. GO:0042986 positive regulation of amyloid precursor protein biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042986 positive regulation of APP biosynthetic process|positive regulation of amyloid precursor protein anabolism|positive regulation of APP biosynthesis|positive regulation of amyloid precursor protein synthesis|positive regulation of amyloid precursor protein biosynthesis|positive regulation of amyloid precursor protein formation|up regulation of amyloid precursor protein biosynthetic process|upregulation of amyloid precursor protein biosynthetic process|stimulation of amyloid precursor protein biosynthetic process|up-regulation of amyloid precursor protein biosynthetic process|activation of amyloid precursor protein biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta. CHEBI:78245 (2-amino-1-hydroxyethyl)phosphonate zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78245 GO:0052300 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052300 CHEBI:78247 (4S)-4-hydroxy-L-isoleucine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78247 GO:0052315 phytoalexin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052315 phytoalexin biosynthesis The chemical reactions and pathways resulting in the formation of phytoalexins, any of a range of substances produced by plants as part of their defense response. GO:0052314 phytoalexin metabolic process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0052314 phytoalexin metabolism The chemical reactions and pathways involving phytoalexins, any of a range of substances produced by plants as part of their defense response. GO:0052313 modulation of nutrient release from other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052313 modulation of nutrient release from other organism during symbiotic interaction Any process in which an organism modulates the frequency, rate or extent of the release of nutrients from a second organism, where the two organisms are in a symbiotic interaction. GO:0052312 modulation of transcription in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052312 modulation of transcription in other organism during symbiotic interaction Any process in which an organism modulates the frequency, rate or extent of transcription in a second organism, where the two organisms are in a symbiotic interaction. GO:0052319 regulation of phytoalexin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052319 regulation of phytoalexin biosynthesis Any process that modulates the frequency, rate or extent of phytoalexin biosynthesis, the chemical reactions and pathways resulting in the formation of phytoalexins. GO:0052318 regulation of phytoalexin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052318 regulation of phytoalexin metabolism Any process that modulates the frequency, rate or extent of phytoalexin metabolism, the chemical reactions and pathways involving phytoalexins, any of a range of substances produced by plants as part of their defense response. GO:0052317 camalexin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052317 camalexin metabolism The chemical reactions and pathways involving camalexin, an indole phytoalexin. GO:0052316 phytoalexin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052316 phytoalexin catabolism The chemical reactions and pathways resulting in the breakdown of phytoalexins, any of a range of substances produced by plants as part of their defense response. CHEBI:20873 CDP-sugar biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20873 GO:0042992 obsolete negative regulation of transcription factor import into nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042992 down-regulation of transcription factor import into nucleus|negative regulation of transcription factor-nucleus import|downregulation of transcription factor import into nucleus|negative regulation of transcription factor import into cell nucleus|down regulation of transcription factor import into nucleus|inhibition of transcription factor import into nucleus|negative regulation of transcription factor transport from cytoplasm to nucleus OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus. CHEBI:29202 isocyanic acid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29202 GO:0042991 obsolete transcription factor import into nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042991 transcription factor-nucleus import|transcription factor import into cell nucleus|transcription factor transport from cytoplasm to nucleus OBSOLETE. The directed movement of a transcription factor from the cytoplasm to the nucleus. GO:0042994 cytoplasmic sequestering of transcription factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042994 transcription factor binding, cytoplasmic sequestering|storage of transcription factor in cytoplasm|retention of transcription factor in cytoplasm|cytoplasmic retention of transcription factor|cytoplasmic storage of transcription factor|sequestering of transcription factor in cytoplasm|maintenance of transcription factor protein location in cytoplasm|cytoplasmic sequestration of transcription factor|sequestration of transcription factor in cytoplasm The selective interaction of a transcription factor with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus. GO:0042993 obsolete positive regulation of transcription factor import into nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042993 stimulation of transcription factor import into nucleus|activation of transcription factor import into nucleus|up-regulation of transcription factor import into nucleus|positive regulation of transcription factor-nucleus import|up regulation of transcription factor import into nucleus|positive regulation of transcription factor import into cell nucleus|upregulation of transcription factor import into nucleus|positive regulation of transcription factor transport from cytoplasm to nucleus OBSOLETE. Any process that activates or increases the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus. GO:0042990 obsolete regulation of transcription factor import into nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042990 regulation of transcription factor transport from cytoplasm to nucleus|regulation of transcription factor-nucleus import|regulation of transcription factor import into cell nucleus OBSOLETE. Any process that modulates the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus. CHEBI:29200 thiocyanic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29200 GO:0042999 regulation of Golgi to plasma membrane CFTR protein transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042999 Any process that modulates the frequency, rate or extent of transport of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein from the Golgi to the plasma membrane. GO:0042996 regulation of Golgi to plasma membrane protein transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042996 Any process that modulates the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane. GO:0042995 cell projection biolink:CellularComponent go-plus goslim_mouse|goslim_agr|goslim_pir|goslim_flybase_ribbon http://purl.obolibrary.org/obo/GO_0042995 cellular process|cell process|cellular projection A prolongation or process extending from a cell, e.g. a flagellum or axon. CHEBI:78252 3-hydroxy-5-methyl-1-naphthoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78252 GO:0042998 positive regulation of Golgi to plasma membrane protein transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042998 up regulation of Golgi to plasma membrane protein transport|upregulation of Golgi to plasma membrane protein transport|stimulation of Golgi to plasma membrane protein transport|up-regulation of Golgi to plasma membrane protein transport|activation of Golgi to plasma membrane protein transport Any process that activates or increases the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane. CHEBI:78251 5-methyl-1-naphthoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78251 GO:0042997 negative regulation of Golgi to plasma membrane protein transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042997 down-regulation of Golgi to plasma membrane protein transport|downregulation of Golgi to plasma membrane protein transport|down regulation of Golgi to plasma membrane protein transport|inhibition of Golgi to plasma membrane protein transport Any process that stops, prevents, or reduces the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane. CHEBI:78256 oryzalexin D biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78256 CHEBI:78255 3alpha-hydroxy-ent-sandaracopimaradiene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78255 CHEBI:20878 CMP-sugar biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_20878 GO:0052311 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052311 GO:0052310 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052310 UBERON:0007425 decussation of diencephalon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007425 diencephalon decussation A neural decussation that is part of a diencephalon. CHEBI:78259 oryzalexin E biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78259 CHEBI:19891 3,4-dihydroxyphenylpyruvic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_19891 GO:0003399 cytoneme morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003399 The process in which the anatomical structures of a cytoneme are shaped. A cytoneme is a long, thin and polarized actin-based cytoplasmic extension that projects from a cell. GO:0003398 glial cell differentiation involved in amphid sensory organ development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003398 The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the amphid sensory organ. GO:0003395 neuron migration involved in dendrite retrograde extension biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003395 The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension of a dendrite. GO:0003394 cell adhesion involved in dendrite retrograde extension biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003394 The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix that contributes to the process of retrograde extension of a dendrite. GO:0003397 neuron migration involved in amphid sensory organ dendrite retrograde extension biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003397 The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension of a dendrite of a neuron in the amphid sensory organ. GO:0003396 cell adhesion involved in amphid sensory organ dendrite retrograde extension biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003396 The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension of a dendrite in a neuron of the amphid sensory organ. GO:0003391 amphid sensory organ dendrite retrograde extension biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003391 The progression of an amphid sensory organ's neuronal dendrite over time by the attachment of a part of the cell to an anchor and the subsequent migration of the cell body away from the anchor point. GO:0003390 dendrite development by retrograde extension biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003390 dendrite retrograde extension The progression of a dendrite over time by the attachment of a part of the neuron to an anchor and the subsequent migration of the cell body away from the anchor point. GO:0003393 neuron migration involved in retrograde extension biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003393 The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension. GO:0003392 cell adhesion involved in retrograde extension biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003392 The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix that contributes to the process of retrograde extension. CHEBI:136688 N-acetyl-alpha-D-glucosaminyl-L-tyrosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136688 CHEBI:136687 2,3-bis-O-(geranylgeranyl)-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136687 CHEBI:136686 (9Z,11S,12Z,15Z)-11-hydroperoxyoctadecatrienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136686 CHEBI:136683 N-arachidonoyl-L-leucine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136683 CHEBI:136682 tembetarine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136682 CHEBI:136699 S-adenosyl-S-carboxymethyl-L-homocysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136699 CHEBI:136698 3-oxochenodeoxycholoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136698 GO:0003377 obsolete regulation of apoptosis by sphingosine-1-phosphate signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003377 regulation of apoptosis by sphingolipid signalling pathway|regulation of apoptosis by sphingolipid signaling pathway OBSOLETE. A sphingosine-1-phosphate signaling pathway that modulates the rate, frequency, or extent of apoptosis. GO:0003376 sphingosine-1-phosphate receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003376 S1P-stimulated signal transduction pathway|S1P-activated G-protein coupled receptor signaling pathway|S1P-activated GPCR signaling pathway|sphingolipid signalling pathway|S1P signaling pathway|S1P receptor signaling pathway|sphingolipid signaling pathway A series of molecular signals initiated by the sphingolipid sphingosine-1-phosphate (S1P) binding to a receptor on the surface of the cell, and which proceeds with the activated receptor transmitting the signal by promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The pathway ends with regulation of a downstream cellular process, e.g. transcription. GO:0003379 establishment of cell polarity involved in gastrulation cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003379 The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell taking part in gastrulation. GO:0003378 obsolete regulation of inflammatory response by sphingosine-1-phosphate signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003378 regulation of inflammatory response by sphingolipid signalling pathway|regulation of inflammatory response by sphingolipid signaling pathway OBSOLETE. A sphingosine-1-phosphate signaling pathway that modulates the rate, frequency, or extent of the inflammatory response. GO:0003373 dynamin family protein polymerization involved in membrane fission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003373 The process of creating dynamin family protein polymers, compounds composed of a large number of dynamin family protein monomers. Dynamin family protein polymers form around lipid tubes and contribute to membrane fission. GO:0003372 establishment or maintenance of cytoskeleton polarity involved in mesendodermal cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003372 Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating mesendodermal cell. GO:0003375 regulation of dynamin family protein polymerization involved in membrane fission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003375 Any process that modulates the rate, frequency, or extent of dynamin family protein polymerization involved in mitochondrial fission. GO:0003374 dynamin family protein polymerization involved in mitochondrial fission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003374 The process of creating dynamin protein family polymers, compounds composed of a large number of dynamin family monomers around a lipid tube of a dividing mitochondrion. Dynamin polymers form around lipid tubes and contribute to membrane fission. GO:0003371 establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003371 Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell. GO:0003370 cell-cell adhesion involved in mesendodermal cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003370 The attachment of mesendodermal cells to each other that contributes to the establishment of cell polarity that is part of the directed movement of the cells of the mesendoderm. CHEBI:136669 (S)-3,4-dihydroxy-2-oxobutanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136669 CHEBI:136668 (R)-3,4-dihydroxy-2-oxobutanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136668 CHEBI:136663 20-hydroxyprostaglandin A1(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136663 CHEBI:136662 (5Z,8R,9E,11Z,14Z,17Z)-8-hydroperoxyicosapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136662 CHEBI:136661 20-hydroxyprostaglandin E1(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136661 GO:0003388 neuron development involved in amphid sensory organ development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003388 The process whose specific outcome is the progression of a neuron over time, that contributes to the development of the amphid sensory organ. GO:0003387 neuron differentiation involved in amphid sensory organ development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003387 The process in which a relatively unspecialized cell acquires specialized features of a neuron that contributes to the progression of the amphid sensory gland. GO:0003389 retrograde extension biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003389 The progression of a neuronal projection over time by the attachment of a part of the cell to an anchor and the subsequent migration of the cell body away from the anchor point. GO:0003384 apical constriction involved in gastrulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003384 The actin-mediated process that results in the contraction of the apical end of a polarized columnar epithelial cell, contributing to the process of gastrulation. GO:0003383 apical constriction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003383 The actin-mediated process that results in the contraction of the apical end of a polarized columnar epithelial cell. GO:0003386 amphid sensory organ development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003386 The progression of the amphid sensory organ over time, from its formation to the mature structure. Amphid sensory organs are the sensory organs of nematodes. GO:0003385 cell-cell signaling involved in amphid sensory organ development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003385 cell-cell signalling involved in amphid sensory organ development Any process that mediates the transfer of information from one cell to another and contributes to the progression of an amphid sensory organ over time, from its formation to the mature state. GO:0003380 establishment or maintenance of cytoskeleton polarity involved in gastrulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003380 Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell taking part in gastrulation. GO:0003382 epithelial cell morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003382 The change in form that occurs when an epithelial cell progresses from its initial formation to its mature state. GO:0003381 epithelial cell morphogenesis involved in gastrulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003381 The change in form that occurs when an epithelial cell progresses from it initial formation to its mature state, contributing to the process of gastrulation. CHEBI:136678 4',7-dihydroxyflavanone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136678 CHEBI:136677 [(S)-1-acetamidoethyl]phosphonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136677 CHEBI:136675 (S)-(1-aminoethyl)phosphonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136675 CHEBI:68819 alpha-D-ribose 1,5-bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68819 CHEBI:136679 (R)-2-amino-4-oxopentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136679 CHEBI:136670 (S)-2,4-dihydroxy-3-oxobutanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136670 CHEBI:136674 (acetamidomethyl)phosphonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136674 CHEBI:136673 epitestosterone 17-O-(beta-D-glucuronide)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136673 CHEBI:136672 N-hexadecanoyl-1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136672 GO:0003359 noradrenergic neuron fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003359 norepinephrine secreting neuron fate commitment The process in which the developmental fate of a cell becomes restricted such that it will develop into a noradrenergic neuron. GO:0003358 noradrenergic neuron development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003358 norepinephrine secreting neuron development The process whose specific outcome is the progression of a noradrenergic neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. GO:0003355 cilium movement involved in otolith formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003355 The directed, self-propelled movement of cilia of inner ear epithelial cells, resulting the aggregation of otolith seed particles. GO:0003354 negative regulation of cilium movement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003354 negative regulation of flagellum movement|negative regulation of microtubule-based flagellum movement Any process that decreases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium. GO:0003357 noradrenergic neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003357 norepinephrine secreting neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron, a neuron that secretes noradrenaline. GO:0003356 regulation of cilium beat frequency biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003356 regulation of microtubule-based flagellum beat frequency|regulation of flagellum beat frequency Any process that modulates the frequency of cilium movement, the directed, self-propelled movement of a cilium. GO:0003351 epithelial cilium movement involved in extracellular fluid movement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003351 epithelial cilium beating|cilium movement involved in fluid flow The directed, self-propelled movement of cilia of epithelial cells. Depending on the type of cell, there may be one or many cilia per cell. This movement is usually coordinated between many epithelial cells, and serves to move extracellular fluid. GO:0003350 pulmonary myocardium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003350 The progression of the pulmonary myocardium over time, from its initial formation to the mature structure. The pulmonary myocardium is the myocardial tissue present in the pulmonary vein. CHEBI:68820 alpha-D-ribose 1-methylphosphonate 5-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68820 GO:0003353 positive regulation of cilium movement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003353 positive regulation of flagellum movement|positive regulation of flagellar movement|positive regulation of microtubule-based flagellum movement Any process that increases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium. CHEBI:68823 alpha-D-ribose 1-methylphosphonate 5-triphosphate(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68823 GO:0003352 regulation of cilium movement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003352 regulation of microtubule-based flagellum movement|regulation of flagellum movement|regulation of flagellar movement Any process that modulates the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium. CHEBI:68822 methylphosphonate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68822 CHEBI:68829 [alpha-D-GalNAc-(1->4)]4-alpha-D-GalNAc-(1->3)-alpha-D-diNAcBac-tritrans,heptacis-undecaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68829 CHEBI:68828 1-deoxy-3-dehydrosphinganine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68828 CHEBI:136642 17alpha-estradiol 17-O-(beta-D-glucuronide)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136642 CHEBI:136649 estriol 3-O-(beta-D-glucuronide)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136649 CHEBI:68825 N,N'-diacetyl-alpha-D-bacillosaminyl-tritrans,heptacis-undecaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68825 CHEBI:68824 alpha-D-ribose 1-methylphosphonate 5-triphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68824 CHEBI:68827 alpha-D-GalNAc-(1->4)-alpha-D-GalNAc-(1->3)-alpha-D-diNAcBac-tritrans,heptacis-undecaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68827 CHEBI:68826 N-acetyl-alpha-D-galactosaminyl-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-tritrans,heptacis-undecaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68826 CHEBI:136641 17beta-estradiol 3-O-(beta-D-glucuronide)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136641 CHEBI:136640 (3R)-1,2-didehydro-3-hydroxy-16-methoxy-2,3-dihydrotabersoninium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136640 GO:0003369 establishment of cell polarity involved in mesendodermal cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003369 The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of a mesendodermal cell. GO:0003366 cell-matrix adhesion involved in ameboidal cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003366 The binding of a cell to the extracellular matrix that contributes to the directed movement of an ameboid cell. GO:0003365 establishment of cell polarity involved in ameboidal cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003365 The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell. GO:0003368 cell-matrix adhesion involved in mesendodermal cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003368 The binding of a cell to the extracellular matrix that contributes to the directed movement of a mesendodermal cell. GO:0003367 cell-cell adhesion involved in ameboidal cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003367 The attachment of one ameboid cell to another that contributes to the establishment of cell polarity that is part of the directed movement of one of the cells. GO:0003362 noradrenergic neuron fate commitment involved in brainstem development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003362 The process in which the developmental fate of a cell becomes restricted such that it will develop into a noradrenergic neuron that is part of the brainstem. CHEBI:68832 1-deoxypentalenic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68832 GO:0003361 noradrenergic neuron differentiation involved in brainstem development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003361 The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron that is part of the brainstem. CHEBI:68831 [alpha-D-GalNAc-(1->4)]2-[beta-D-Glc-(1->3)]-[alpha-D-GalNAc-(1->4)]2-alpha-D-GalNAc-(1->3)-alpha-D-diNAcBac-tritrans,heptacis-undecaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68831 GO:0003364 lamellipodium assembly involved in mesendodermal cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003364 Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell that contributes to the directed self-propelled movement of a mesendodermal cell. GO:0003363 lamellipodium assembly involved in ameboidal cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003363 Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell that contributes to the directed self propelled movement of a cell. GO:0003360 brainstem development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003360 The progression of the brainstem from its formation to the mature structure. The brainstem is the part of the brain that connects the brain with the spinal cord. CHEBI:68830 O-decanoylcarnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68830 CHEBI:136656 (5Z,9E,11Z,14Z,17Z)-8-hydroperoxyicosapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136656 CHEBI:136655 13(R)-HODE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136655 CHEBI:136654 13(S)-HETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136654 CHEBI:136653 20-hydroxyprostaglandin E2(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136653 CHEBI:68836 diphosphate group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_68836 CHEBI:68837 pectate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68837 CHEBI:136657 (4Z,7Z,11E,13Z,16Z,19Z)-10-hydroperoxydocosahexaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136657 CHEBI:30297 antimonite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30297 CHEBI:136650 estriol 16-O-(beta-D-glucuronide)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136650 GO:0003337 mesenchymal to epithelial transition involved in metanephros morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003337 metanephric mesenchyme to epithelial transition A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros. GO:0003336 corneocyte desquamation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003336 epidermal desquamation The delamination process that results in the shedding of a corneocyte from the surface of the epidermis. GO:0003339 regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003339 Any process that modulates the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros. GO:0003338 metanephros morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003338 The process in which the anatomical structures of the metanephros are generated and organized. GO:0003333 amino acid transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003333 amino acid membrane transport The process in which an amino acid is transported across a membrane. GO:0003332 negative regulation of extracellular matrix constituent secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003332 Any process that decreases the rate, frequency, or extent the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells. GO:0003335 corneocyte development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003335 The process whose specific outcome is the progression of the corneocyte over time, from its formation to the mature structure. A corneocyte is the last stage of development of a keratinocyte where the keratinocyte flattens, loses its nucleus and eventually delaminates from the epidermis. GO:0003334 keratinocyte development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003334 The process whose specific outcome is the progression of a keratinocyte over time, from its formation to the mature structure. CHEBI:29279 sulfurothioic O-acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29279 CHEBI:29278 dinitride(4-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29278 GO:0003331 positive regulation of extracellular matrix constituent secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003331 Any process that increases the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells. GO:0003330 regulation of extracellular matrix constituent secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003330 Any process that modulates the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells. CHEBI:29277 dinitride(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29277 CHEBI:136623 N-octadecanoylglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136623 GO:0042901 arabinan transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042901 Enables the transfer of an arabinan, a polysaccharide composed of arabinose residues, from one side of a membrane to the other. CHEBI:30260 cyromazine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30260 GO:0042900 arabinose transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042900 Enables the transfer of arabinose, a pentose monosaccharide that occurs in both D and L configurations, and as a polymer, from one side of a membrane to the other. CHEBI:29281 alkyl sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29281 CHEBI:136622 aci-nitro compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136622 GO:0042903 tubulin deacetylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042903 Reactome:R-HSA-5618331 Catalysis of the reaction: N-acetyl(alpha-tubulin) + H2O = alpha-tubulin + acetate. GO:0042902 peptidoglycan-protein cross-linking via L-threonyl-pentaglycyl-murein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042902 RESID:AA0345 The process of linking a protein to peptidoglycan via a carboxy terminal threonine carboxyl group through a pentaglycyl peptide to the lysine or diaminopimelic acid of the peptidoglycan. CHEBI:136627 hydroperoxyicosatrienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136627 CHEBI:136626 (8R,9E,11Z,14Z)-8-hydroperoxyicosatrienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136626 CHEBI:136625 2-O-(alpha-D-mannopyranosyl)-6-O-(6-acyl-alpha-D-mannopyranosyl)-1-phosphatidyl-1D-myo-inositol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136625 CHEBI:136624 2,6-O-bis(alpha-D-mannopyranosyl)-1-phosphatidyl-1D-myo-inositol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136624 GO:0042909 acridine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042909 The directed movement of acridine (10-azaanthracene), a heterocyclic ring compound found in crude coal-tar anthracene, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0042908 xenobiotic transport biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0042908 The directed movement of a xenobiotic, a compound foreign to living organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0042905 9-cis-retinoic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042905 9-cis-retinoic acid metabolism The chemical reactions and pathways involving 9-cis-retinoic acid, a metabolically active vitamin A derivative. GO:0042904 9-cis-retinoic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042904 9-cis-retinoic acid biosynthesis|9-cis-retinoic acid anabolism|9-cis-retinoic acid synthesis|9-cis-retinoic acid formation The chemical reactions and pathways resulting in the formation of 9-cis-retinoic acid, a metabolically active vitamin A derivative. GO:0042907 xanthine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042907 Enables the transfer of xanthine from one side of a membrane to the other. Xanthine (2,6-dihydroxypurine) is a purine formed in the metabolic breakdown of guanine, but is not present in nucleic acids. GO:0042906 xanthine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042906 xanthine transmembrane transport The directed movement of xanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Xanthine (2,6-dihydroxypurine) is a purine formed in the metabolic breakdown of guanine, but is not present in nucleic acids. GO:0003348 cardiac endothelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003348 The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac endothelial cell. GO:0003347 epicardial cell to mesenchymal cell transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003347 A transition where an epicardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. The epicardium is a part of the pericardium. GO:0003349 epicardium-derived cardiac endothelial cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003349 The process in which an epicardial cell acquires the specialized structural and/or functional features of a cardiac endothelial cell. GO:0003344 pericardium morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003344 The process in which the anatomical structure of the pericardium is generated and organized. GO:0003343 septum transversum development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003343 The progression of the septum transversum from its initial formation to the mature structure. The septum transversum is a portion of the trunk mesenchyme. GO:0003346 epicardium-derived cell migration to the myocardium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003346 The orderly movement of a cell that have undergone an epithelial to mesenchymal transition from the epicardium into the myocardium. GO:0003345 proepicardium cell migration involved in pericardium morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003345 The coordinated movement of a mesenchymal proepicardial cell to the surface of the developing heart. GO:0003340 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003340 Any process that decreases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros. CHEBI:29289 S-alkyl thiosulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29289 GO:0003342 proepicardium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003342 The progression of the proepicardium from its formation to the mature structure. The proepicardium is an outpouching of the septum transversum. GO:0003341 cilium movement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003341 ciliary motility|flagellar motility|microtubule-based flagellum movement|flagellum movement|flagellar movement|cilium beating The directed, self-propelled movement of a cilium. CHEBI:136639 testosterone 17-O-(beta-D-glucuronide)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136639 CHEBI:29287 gold atom biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29287 CHEBI:68851 poly(glycerol phosphate) anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_68851 GO:0042912 colicin transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042912 Enables the transfer of a colicin from one side of a membrane to the other. Colicins are a group of antibiotics produced by E. coli and related species that are encoded by a group of naturally occurring plasmids, e.g. Col E1. CHEBI:136634 estrone 3-O-(beta-D-glucuronide)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136634 GO:0042911 acridine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042911 acridine transporter activity Enables the directed movement of acridine (10-azaanthracene), a heterocyclic ring compound found in crude coal-tar anthracene from one side of a membrane to the other. CHEBI:136633 (9Z,11Z,13S,15Z)-12,13-epoxyoctadecatrienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136633 GO:0042914 colicin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042914 The directed movement of a colicin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Colicins are a group of antibiotics produced by E. coli and related species that are encoded by a group of naturally occurring plasmids, e.g. Col E1. CHEBI:136632 (5Z,8R,9Z,11Z,14Z)-8,9-epoxyicosatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136632 GO:0042913 group A colicin transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042913 Enables the transfer of group A colicins (colicins E1, E2, E3, A, K, and N) from one side of a membrane to the other. CHEBI:136631 (8Z,12E,14Z)-11-hydroperoxyicosatrienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136631 CHEBI:136638 9-hydroxyoctadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136638 CHEBI:136637 steroid glucosiduronic acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136637 GO:0042910 xenobiotic transmembrane transporter activity biolink:MolecularActivity go-plus goslim_metagenomics http://purl.obolibrary.org/obo/GO_0042910 xenobiotic transporter activity|multidrug transporter activity|drug transmembrane transporter activity|drug transporter activity|multidrug efflux pump activity|multidrug, alkane resistant pump activity Enables the directed movement of a xenobiotic from one side of a membrane to the other. A xenobiotic is a compound foreign the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. CHEBI:136636 16alpha-hydroxyestrone 16-O-(beta-D-glucuronide)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136636 CHEBI:136635 16alpha-hydroxyestrone 3-O-(beta-D-glucuronide)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136635 GO:0042919 benzoate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042919 The directed movement of benzoate, the anion of benzoic acid (benzenecarboxylic acid) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:136630 (8Z,11Z,14Z)-10-hydroperoxyicosatrienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136630 GO:0042916 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042916 GO:0042915 group A colicin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042915 The directed movement of group A colicins (colicins E1, E2, E3, A, K, and N) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0042918 alkanesulfonate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042918 alkanesulphonate transport The directed movement of an alkanesulfonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alkanesulfonates are organic esters or salts of sulfonic acid containing an aliphatic hydrocarbon radical. GO:0042917 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042917 UBERON:0007095 somatic musculature biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007095 CHEBI:15409 (-)-menthol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15409 CHEBI:15408 (-)-isopiperitenone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15408 GO:1904279 regulation of transcription by RNA polymerase V biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904279 regulation of transcription from RNA pol V promoter|regulation of transcription from RNA polymerase V promoter Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase V. GO:1904278 positive regulation of wax biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904278 up regulation of wax anabolism|positive regulation of wax anabolism|activation of wax anabolism|upregulation of wax biosynthesis|upregulation of wax biosynthetic process|up regulation of wax synthesis|positive regulation of wax synthesis|activation of wax synthesis|up regulation of wax formation|positive regulation of wax formation|activation of wax formation|up-regulation of wax biosynthesis|up-regulation of wax biosynthetic process|activation of wax biosynthetic process|activation of wax biosynthesis|up-regulation of wax anabolism|up-regulation of wax synthesis|up-regulation of wax formation|upregulation of wax anabolism|positive regulation of wax biosynthesis|up regulation of wax biosynthetic process|up regulation of wax biosynthesis|upregulation of wax synthesis|upregulation of wax formation Any process that activates or increases the frequency, rate or extent of wax biosynthetic process. GO:1904288 BAT3 complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1904288 BAG6-UBL4A-TRC35 complex binding|BAT3-TRC35-UBL4A complex binding|Bag6 complex binding Interacting selectively and non-covalently with a BAT3 complex. CHEBI:15405 (-)-endo-fenchol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15405 GO:1904287 positive regulation of protein-pyridoxal-5-phosphate linkage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904287 stimulation of protein-pyridoxal-5-phosphate linkage|up regulation of protein-pyridoxal-5-phosphate linkage|activation of protein-pyridoxal-5-phosphate linkage|up-regulation of protein-pyridoxal-5-phosphate linkage|upregulation of protein-pyridoxal-5-phosphate linkage Any process that activates or increases the frequency, rate or extent of protein-pyridoxal-5-phosphate linkage. CHEBI:15404 (-)-homoisocitrate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15404 GO:1904286 negative regulation of protein-pyridoxal-5-phosphate linkage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904286 down regulation of protein-pyridoxal-5-phosphate linkage|downregulation of protein-pyridoxal-5-phosphate linkage|down-regulation of protein-pyridoxal-5-phosphate linkage|inhibition of protein-pyridoxal-5-phosphate linkage Any process that stops, prevents or reduces the frequency, rate or extent of protein-pyridoxal-5-phosphate linkage. CHEBI:15407 (-)-ephedrine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15407 GO:1904285 regulation of protein-pyridoxal-5-phosphate linkage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904285 Any process that modulates the frequency, rate or extent of protein-pyridoxal-5-phosphate linkage. CHEBI:15406 (-)-trans-isopiperitenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15406 GO:1904284 positive regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904284 activation of endogenous peptide antigen processing and presentation via MHC class I|up regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I|activation of antigen processing and presentation of endogenous peptide antigen via MHC class I|positive regulation of endogenous peptide antigen processing and presentation via MHC class I|up regulation of endogenous peptide antigen processing and presentation via MHC class I|up-regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I|upregulation of endogenous peptide antigen processing and presentation via MHC class I|upregulation of antigen processing and presentation of endogenous peptide antigen via MHC class I|up-regulation of endogenous peptide antigen processing and presentation via MHC class I Any process that activates or increases the frequency, rate or extent of antigen processing and presentation of endogenous peptide antigen via MHC class I. UBERON:0007099 hyoid neural crest biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007099 hyoid crest Cranial neural crest that migrates into the hyoid arch. CHEBI:15401 (+)-dihydrokaempferol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15401 GO:1904283 negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904283 downregulation of antigen processing and presentation of endogenous peptide antigen via MHC class I|down-regulation of endogenous peptide antigen processing and presentation via MHC class I|negative regulation of endogenous peptide antigen processing and presentation via MHC class I|down-regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I|downregulation of endogenous peptide antigen processing and presentation via MHC class I|inhibition of antigen processing and presentation of endogenous peptide antigen via MHC class I|down regulation of endogenous peptide antigen processing and presentation via MHC class I|inhibition of endogenous peptide antigen processing and presentation via MHC class I|down regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I Any process that stops, prevents or reduces the frequency, rate or extent of antigen processing and presentation of endogenous peptide antigen via MHC class I. UBERON:0007098 mandibular neural crest biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007098 Cranial neural crest that migrates into the mandibular arch. CHEBI:15400 (-)-carvone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15400 GO:1904282 regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904282 regulation of antigen presentation, endogenous peptide antigen|regulation of antigen processing, endogenous antigen via MHC class I|regulation of antigen processing, endogenous antigen via major histocompatibility complex class I|regulation of endogenous peptide antigen processing and presentation via MHC class I Any process that modulates the frequency, rate or extent of antigen processing and presentation of endogenous peptide antigen via MHC class I. CHEBI:15403 (+)-sabinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15403 GO:1904281 positive regulation of transcription by RNA polymerase V biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904281 up regulation of transcription from RNA pol V promoter|up-regulation of transcription from RNA polymerase V promoter|activation of transcription from RNA polymerase V promoter|positive regulation of transcription from RNA pol V promoter|activation of transcription from RNA pol V promoter|up-regulation of transcription from RNA pol V promoter|up regulation of transcription from RNA polymerase V promoter|upregulation of transcription from RNA pol V promoter|upregulation of transcription from RNA polymerase V promoter|positive regulation of transcription from RNA polymerase V promoter Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase V. CHEBI:15402 (+)-neomenthol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15402 GO:1904280 negative regulation of transcription by RNA polymerase V biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904280 down-regulation of transcription from RNA pol V promoter|negative regulation of transcription from RNA pol V promoter|down-regulation of transcription from RNA polymerase V promoter|inhibition of transcription from RNA pol V promoter|downregulation of transcription from RNA polymerase V promoter|down regulation of transcription from RNA polymerase V promoter|inhibition of transcription from RNA polymerase V promoter|negative regulation of transcription from RNA polymerase V promoter|down regulation of transcription from RNA pol V promoter|downregulation of transcription from RNA pol V promoter Any process that stops, prevents or reduces the frequency, rate or extent of transcription mediated by RNA polymerase V. GO:1904289 regulation of mitotic DNA damage checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904289 Any process that modulates the frequency, rate or extent of mitotic DNA damage checkpoint. GO:1904299 negative regulation of transcytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904299 down-regulation of transcytosis|downregulation of transcytosis|down regulation of transcytosis|inhibition of transcytosis Any process that stops, prevents or reduces the frequency, rate or extent of transcytosis. GO:1904298 regulation of transcytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904298 Any process that modulates the frequency, rate or extent of transcytosis. GO:1904297 positive regulation of osmolarity-sensing cation channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904297 up regulation of osmolarity-sensing cation channel activity|upregulation of osmolarity-sensing cation channel activity|activation of osmolarity-sensing cation channel activity|up-regulation of osmolarity-sensing cation channel activity Any process that activates or increases the frequency, rate or extent of osmolarity-sensing cation channel activity. GO:1904296 negative regulation of osmolarity-sensing cation channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904296 downregulation of osmolarity-sensing cation channel activity|down regulation of osmolarity-sensing cation channel activity|inhibition of osmolarity-sensing cation channel activity|down-regulation of osmolarity-sensing cation channel activity Any process that stops, prevents or reduces the frequency, rate or extent of osmolarity-sensing cation channel activity. GO:1904295 regulation of osmolarity-sensing cation channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904295 Any process that modulates the frequency, rate or extent of osmolarity-sensing cation channel activity. GO:1904294 positive regulation of ERAD pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904294 upregulation of ERAD pathway|positive regulation of endoplasmic reticulum-associated degradation|upregulation of ER-associated degradation pathway|up regulation of endoplasmic reticulum-associated degradation|upregulation of endoplasmic reticulum-associated protein degradation pathway|up-regulation of ERAD pathway|activation of ERAD pathway|up regulation of ER-associated degradation pathway|upregulation of endoplasmic reticulum-associated degradation|positive regulation of ER-associated degradation pathway|up-regulation of endoplasmic reticulum-associated protein degradation pathway|activation of ER-associated degradation pathway|up regulation of ERAD pathway|activation of endoplasmic reticulum-associated protein degradation pathway|up-regulation of endoplasmic reticulum-associated degradation|activation of endoplasmic reticulum-associated degradation|up-regulation of ER-associated degradation pathway|positive regulation of endoplasmic reticulum-associated protein degradation pathway|up regulation of endoplasmic reticulum-associated protein degradation pathway Any process that activates or increases the frequency, rate or extent of ERAD pathway. GO:1904293 negative regulation of ERAD pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904293 inhibition of ERAD pathway|negative regulation of endoplasmic reticulum-associated degradation|down-regulation of endoplasmic reticulum-associated degradation|inhibition of ER-associated degradation pathway|downregulation of endoplasmic reticulum-associated protein degradation pathway|down regulation of endoplasmic reticulum-associated protein degradation pathway|down regulation of ER-associated degradation pathway|downregulation of endoplasmic reticulum-associated degradation|downregulation of ER-associated degradation pathway|inhibition of endoplasmic reticulum-associated protein degradation pathway|down regulation of endoplasmic reticulum-associated degradation|inhibition of endoplasmic reticulum-associated degradation|down-regulation of ERAD pathway|down-regulation of ER-associated degradation pathway|negative regulation of ER-associated degradation pathway|down-regulation of endoplasmic reticulum-associated protein degradation pathway|negative regulation of endoplasmic reticulum-associated protein degradation pathway|downregulation of ERAD pathway|down regulation of ERAD pathway Any process that stops, prevents or reduces the frequency, rate or extent of ERAD pathway. GO:1904292 regulation of ERAD pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904292 regulation of endoplasmic reticulum-associated protein degradation pathway|regulation of ER-associated degradation pathway|regulation of endoplasmic reticulum-associated degradation Any process that modulates the frequency, rate or extent of ERAD pathway. GO:1904291 positive regulation of mitotic DNA damage checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904291 up-regulation of mitotic DNA damage checkpoint|upregulation of mitotic DNA damage checkpoint|up regulation of mitotic DNA damage checkpoint|activation of mitotic DNA damage checkpoint Any process that activates or increases the frequency, rate or extent of mitotic DNA damage checkpoint. GO:1904290 negative regulation of mitotic DNA damage checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904290 inhibition of mitotic DNA damage checkpoint|down regulation of mitotic DNA damage checkpoint|downregulation of mitotic DNA damage checkpoint|down-regulation of mitotic DNA damage checkpoint Any process that stops, prevents or reduces the frequency, rate or extent of mitotic DNA damage checkpoint. CHEBI:15427 N(2)-(2-carboxyethyl)-L-arginine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15427 CHEBI:15426 deoxyamidinoproclavaminic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15426 CHEBI:15429 hydroxylamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15429 CHEBI:15428 glycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15428 CHEBI:15423 clavaminic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15423 CHEBI:15422 ATP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15422 CHEBI:15425 proclavaminic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15425 CHEBI:15424 dihydroclavaminic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15424 CHEBI:15421 perillyl aldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15421 CHEBI:15420 perillyl alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15420 CHEBI:15419 ent-7alpha-hydroxykaur-16-en-19-oic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15419 CHEBI:15416 ent-kaur-16-en-19-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15416 CHEBI:15415 ent-kaurene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15415 CHEBI:15418 ent-kaur-16-en-19-al biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15418 CHEBI:15417 ent-kaur-16-en-19-oic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15417 CHEBI:15412 (-)-ureidoglycolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15412 CHEBI:15411 (-)-menthyl beta-D-glucoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15411 CHEBI:15414 S-adenosyl-L-methionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15414 CHEBI:15413 2',4,4',6'-tetrahydroxychalcone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15413 CHEBI:15410 (-)-menthone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15410 CHEBI:8871 risperidone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_8871 CHEBI:64405 F-9775A biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64405 CHEBI:64409 F-9775B biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64409 CHEBI:64406 EC 3.4.22.38 (cathepsin K) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64406 CHEBI:64411 EC 2.5.1.29 (geranylgeranyl diphosphate synthase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64411 CHEBI:64410 gerfelin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64410 CHEBI:64416 EC 1.3.1.43 (arogenate dehydrogenase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64416 CHEBI:64415 violaceol I biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64415 CHEBI:64413 diorcinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64413 CHEBI:64419 meroterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64419 CHEBI:64418 austinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64418 CHEBI:64417 violaceol II biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64417 GO:0052447 obsolete modulation by organism of symbiont ethylene-mediated defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052447 modulation by organism of symbiont ethylene-mediated defense response OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the ethylene-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052446 obsolete modulation by organism of defense-related symbiont cell wall thickening biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052446 modulation by organism of symbiont defensive cell wall thickening|modulation by organism of defense-related symbiont cell wall thickening OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of symbiont processes resulting in the thickening of its cell walls, occurring as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052445 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052445 CHEBI:15490 3-oxoadipyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15490 GO:0052444 obsolete modulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052444 modulation of defense-related symbiont SA-mediated signal transduction pathway by organism|modulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of symbiont salicylic acid-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052449 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052449 GO:0052448 obsolete modulation by organism of ethylene levels in symbiont biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052448 modulation by organism of ethylene levels in symbiont OBSOLETE. The alteration by an organism of the levels of ethylene in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. PR:000002198 catenin beta-1 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000002198 CTNNB|beta-catenin|Catnb|CTNNB1 A protein that is a translation product of the human CTNNB1 gene or a 1:1 ortholog thereof. GO:1904200 iodide transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904200 The process in which iodide is transported across a membrane. CHEBI:39457 pyrimidine ribonucleoside 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39457 CHEBI:15489 3-oxo-fatty acyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15489 CHEBI:15488 trans-3-methylglutaconyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15488 UBERON:0007010 cleaving embryo biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007010 Organism at the cleavage stage. CHEBI:15485 3-hydroxypimeloyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15485 CHEBI:15484 3-hydroxybenzoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15484 CHEBI:39450 trans-undec-2-enoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39450 CHEBI:15487 isovaleryl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15487 CHEBI:15486 3-methylbut-2-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15486 GO:0052443 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052443 CHEBI:39456 antiglaucoma drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39456 CHEBI:15481 3-hydroxy-2-methylpropanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15481 GO:0052442 obsolete modulation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052442 modulation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway|modulation of defense-related symbiont JA-mediated signal transduction pathway by organism OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of symbiont jasmonic acid-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:15480 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15480 GO:0052441 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052441 CHEBI:15483 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15483 GO:0052440 obsolete modulation by organism of defense-related symbiont ethylene-mediated signal transduction pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052440 modulation by organism of defense-related symbiont ethylene-mediated signal transduction pathway OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of symbiont ethylene-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052458 obsolete modulation by organism of symbiont non-apoptotic programmed cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052458 modulation by organism of symbiont non-apoptotic programmed cell death OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of programmed cell death in the symbiont, where programmed cell death proceeds by a non-apoptotic pathway. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052457 obsolete modulation by organism of defense-related symbiont nitric oxide production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052457 modulation by organism of defense-related symbiont nitric oxide production|modulation by organism of defense-related symbiont NO production OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the production of nitric oxide as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052456 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052456 GO:0052455 obsolete modulation by organism of jasmonic acid levels in symbiont biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052455 modulation by organism of jasmonic acid levels in symbiont OBSOLETE. The alteration by an organism of the levels of jasmonic acid in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052459 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052459 GO:1904209 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1904209 GO:1904208 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1904208 GO:1904207 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1904207 GO:1904206 positive regulation of skeletal muscle hypertrophy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904206 upregulation of skeletal muscle hypertrophy|up regulation of skeletal muscle hypertrophy|activation of skeletal muscle hypertrophy|up-regulation of skeletal muscle hypertrophy Any process that activates or increases the frequency, rate or extent of skeletal muscle hypertrophy. GO:1904205 negative regulation of skeletal muscle hypertrophy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904205 down regulation of skeletal muscle hypertrophy|downregulation of skeletal muscle hypertrophy|down-regulation of skeletal muscle hypertrophy|inhibition of skeletal muscle hypertrophy Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle hypertrophy. GO:1904204 regulation of skeletal muscle hypertrophy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904204 Any process that modulates the frequency, rate or extent of skeletal muscle hypertrophy. GO:1904203 positive regulation of iodide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904203 upregulation of iodide transport|up-regulation of iodide transport|activation of iodide transport|up regulation of iodide transport Any process that activates or increases the frequency, rate or extent of iodide transport. GO:1904202 negative regulation of iodide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904202 downregulation of iodide transport|down regulation of iodide transport|inhibition of iodide transport|down-regulation of iodide transport Any process that stops, prevents or reduces the frequency, rate or extent of iodide transport. GO:1904201 regulation of iodide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904201 Any process that modulates the frequency, rate or extent of iodide transport. GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904211 membrane protein proteolysis involved in retrograde protein transport, endoplasmic reticulum to cytosol|membrane protein proteolysis involved in protein retrotranslocation, ER to cytosol|intramembrane cleavage of ERAD substrate|intramembrane proteolysis involved in ERAD|membrane protein proteolysis involved in protein dislocation from ER Any membrane protein proteolysis that is involved in retrograde protein transport, ER to cytosol. GO:1904210 VCP-NPL4-UFD1 AAA ATPase complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904210 Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|VCP-NPL4-UFD1 AAA ATPase complex formation|p97-Ufd1-Npl4 complex assembly|p97-Ufd1-Npl4 complex formation The aggregation, arrangement and bonding together of a set of components to form a VCP-NPL4-UFD1 AAA ATPase complex. CHEBI:15478 2-methylcrotonoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15478 CHEBI:15477 2-methylbutanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15477 CHEBI:15479 isobutyryl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15479 GO:0052450 obsolete modulation by organism of induced systemic resistance in symbiont biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052450 modulation by organism of induced systemic resistance in symbiont OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of induced systemic resistance in the symbiont organism; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:15474 2-furoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15474 CHEBI:15473 crotonoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15473 CHEBI:15476 2-methylacetoacetyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15476 CHEBI:15475 2-hydroxyphytanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15475 GO:0052454 obsolete modulation by organism of symbiont jasmonic acid-mediated defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052454 modulation by organism of symbiont jasmonic acid-mediated defense response|modulation by organism of symbiont JA-mediated defense response OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the jasmonic acid-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:15470 2,4-dichlorobenzoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15470 GO:0052453 obsolete modulation by organism of symbiont intracellular transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052453 modulation of symbiont intracellular trafficking|modulation by organism of symbiont intracellular transport OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the directed movement of substances within the cell or cells of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052452 obsolete modulation by organism of symbiont innate immunity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052452 modulation by organism of symbiont innate immunity|modulation of symbiont innate immune response OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the innate immune response of the symbiont organism; the innate immune response is the symbiont's first line of defense against infection. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:15472 anthraniloyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15472 GO:0052451 obsolete modulation by organism of symbiont inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052451 modulation by organism of symbiont inflammatory response OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the inflammatory response of a symbiont organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:15471 trans-dodec-2-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15471 UBERON:0007005 cardiogenic splanchnic mesoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007005 cardiogenic region|cardiogenic mesoderm|cardiogenic splanchnopleure|heart primordia|cardiac mesoderm The splanchnic mesoderm in the cardiogenic region where the heart develops; it gives rise to endocardial heart tubes that fuse to form the primordial cardiac tube, the heart primordium[web]. Two migratory heart primordia that move ventrally during the course of neurulation, and then fuse[XAO]. GO:0052469 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052469 GO:0052468 obsolete modulation by organism of salicylic acid levels in symbiont biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052468 modulation by organism of salicylic acid levels in symbiont OBSOLETE. The alteration by an organism of the levels of salicylic acid in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052467 obsolete modulation by organism of symbiont salicylic acid-mediated defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052467 modulation by organism of symbiont salicylic acid-mediated defense response|modulation by organism of symbiont SA-mediated defense response OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the salicylic acid-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052466 obsolete modulation by organism of symbiont resistance gene-dependent defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052466 modulation by organism of defense response in symbiont by specific elicitors|modulation by organism of symbiont gene-for-gene resistance|modulation by organism of symbiont resistance gene-dependent defense response|modulation by organism of pathogen-race/symbiont plant cultivar-specific resistance in symbiont OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the resistance gene-dependent defense response of the symbiont. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:1904219 positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904219 upregulation of phosphatidylserine synthase activity|up-regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|up-regulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|upregulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|positive regulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|up regulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|up regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity|positive regulation of phosphatidylserine synthetase activity|up regulation of CDP-diglycerine-serine O-phosphatidyltransferase activity|up regulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|activation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|positive regulation of PS synthase activity|upregulation of CDPdiglyceride-serine O-phosphatidyltransferase activity|up regulation of CDP-diglyceride:serine phosphatidyltransferase activity|positive regulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|up-regulation of CDP-diglyceride-L-serine phosphatidyltransferase activity|positive regulation of CDP-diglycerine-serine O-phosphatidyltransferase activity|upregulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|activation of CDP-diglycerine-serine O-phosphatidyltransferase activity|up regulation of phosphatidylserine synthetase activity|positive regulation of CDP-diglyceride:serine phosphatidyltransferase activity|up regulation of PS synthase activity|activation of CDP-diglyceride:serine phosphatidyltransferase activity|up-regulation of phosphatidylserine synthase activity|activation of phosphatidylserine synthase activity|upregulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|upregulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|up-regulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|activation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|up-regulation of CDPdiglyceride-serine O-phosphatidyltransferase activity|upregulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity|up-regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|upregulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|upregulation of CDP-diglyceride-L-serine phosphatidyltransferase activity|activation of CDPdiglyceride-serine O-phosphatidyltransferase activity|upregulation of phosphatidylserine synthetase activity|activation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|up-regulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|up-regulation of CDP-diglycerine-serine O-phosphatidyltransferase activity|upregulation of PS synthase activity|up-regulation of CDP-diglyceride:serine phosphatidyltransferase activity|up regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|positive regulation of phosphatidylserine synthase activity|up regulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|up regulation of phosphatidylserine synthase activity|activation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|positive regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|activation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|positive regulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|positive regulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|up-regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity|up-regulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|up regulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|activation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity|up-regulation of phosphatidylserine synthetase activity|up regulation of CDP-diglyceride-L-serine phosphatidyltransferase activity|positive regulation of CDPdiglyceride-serine O-phosphatidyltransferase activity|activation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|upregulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|activation of phosphatidylserine synthetase activity|upregulation of CDP-diglycerine-serine O-phosphatidyltransferase activity|positive regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|up-regulation of PS synthase activity|activation of CDP-diglyceride-L-serine phosphatidyltransferase activity|up regulation of CDPdiglyceride-serine O-phosphatidyltransferase activity|activation of PS synthase activity|upregulation of CDP-diglyceride:serine phosphatidyltransferase activity|positive regulation of CDP-diglyceride-L-serine phosphatidyltransferase activity|up regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity Any process that activates or increases the frequency, rate or extent of CDP-diacylglycerol-serine O-phosphatidyltransferase activity. GO:1904218 negative regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904218 down-regulation of CDP-diglyceride-L-serine phosphatidyltransferase activity|negative regulation of CDP-diglyceride-L-serine phosphatidyltransferase activity|down regulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|down-regulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|downregulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|negative regulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|inhibition of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|downregulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|inhibition of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|inhibition of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|down-regulation of phosphatidylserine synthetase activity|negative regulation of phosphatidylserine synthetase activity|downregulation of CDP-diglycerine-serine O-phosphatidyltransferase activity|negative regulation of PS synthase activity|down-regulation of PS synthase activity|down regulation of CDPdiglyceride-serine O-phosphatidyltransferase activity|downregulation of CDP-diglyceride:serine phosphatidyltransferase activity|down regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|inhibition of CDPdiglyceride-serine O-phosphatidyltransferase activity|inhibition of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|inhibition of CDP-diglyceride-L-serine phosphatidyltransferase activity|downregulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity|downregulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|negative regulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|down-regulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|downregulation of phosphatidylserine synthetase activity|downregulation of PS synthase activity|down-regulation of CDP-diglycerine-serine O-phosphatidyltransferase activity|negative regulation of CDP-diglycerine-serine O-phosphatidyltransferase activity|down regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity|negative regulation of CDP-diglyceride:serine phosphatidyltransferase activity|down-regulation of CDP-diglyceride:serine phosphatidyltransferase activity|down regulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|down regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|inhibition of CDP-diacylglycerol-serine O-phosphatidyltransferase activity|down regulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|down regulation of phosphatidylserine synthetase activity|inhibition of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|down regulation of PS synthase activity|inhibition of phosphatidylserine synthetase activity|down-regulation of phosphatidylserine synthase activity|inhibition of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|inhibition of PS synthase activity|negative regulation of phosphatidylserine synthase activity|inhibition of CDP-diglycerine-serine O-phosphatidyltransferase activity|downregulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|downregulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|inhibition of CDP-diglyceride:serine phosphatidyltransferase activity|down regulation of CDP-diglyceride-L-serine phosphatidyltransferase activity|down-regulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|negative regulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|down-regulation of CDPdiglyceride-serine O-phosphatidyltransferase activity|negative regulation of CDPdiglyceride-serine O-phosphatidyltransferase activity|down-regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|negative regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|downregulation of CDP-diglyceride-L-serine phosphatidyltransferase activity|downregulation of phosphatidylserine synthase activity|down-regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|negative regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|down-regulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|negative regulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|downregulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|down regulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|down regulation of phosphatidylserine synthase activity|inhibition of phosphatidylserine synthase activity|down regulation of CDP-diglycerine-serine O-phosphatidyltransferase activity|downregulation of CDPdiglyceride-serine O-phosphatidyltransferase activity|down regulation of CDP-diglyceride:serine phosphatidyltransferase activity|down-regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity Any process that stops, prevents or reduces the frequency, rate or extent of CDP-diacylglycerol-serine O-phosphatidyltransferase activity. GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904217 regulation of CDP-diglyceride:serine phosphatidyltransferase activity|regulation of CDPdiglyceride-serine O-phosphatidyltransferase activity|regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|regulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|regulation of phosphatidylserine synthetase activity|regulation of PS synthase activity|regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|regulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|regulation of CDP-diglyceride-L-serine phosphatidyltransferase activity|regulation of serine exchange enzyme|regulation of phosphatidylserine synthase activity|regulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|regulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|regulation of CDP-diglycerine-serine O-phosphatidyltransferase activity Any process that modulates the frequency, rate or extent of CDP-diacylglycerol-serine O-phosphatidyltransferase activity. GO:1904216 positive regulation of protein import into chloroplast stroma biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904216 up regulation of chloroplast stroma protein import|up-regulation of protein import into chloroplast stroma|activation of protein import into chloroplast stroma|activation of chloroplast stroma protein import|up-regulation of protein transport into chloroplast stroma|positive regulation of chloroplast stroma protein import|upregulation of protein transport into chloroplast stroma|up-regulation of chloroplast stroma protein import|up regulation of protein import into chloroplast stroma|up regulation of protein transport into chloroplast stroma|activation of protein transport into chloroplast stroma|upregulation of chloroplast stroma protein import|positive regulation of protein transport into chloroplast stroma|upregulation of protein import into chloroplast stroma Any process that activates or increases the frequency, rate or extent of protein import into chloroplast stroma. GO:1904215 regulation of protein import into chloroplast stroma biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904215 regulation of protein transport into chloroplast stroma|regulation of chloroplast stroma protein import Any process that modulates the frequency, rate or extent of protein import into chloroplast stroma. GO:1904214 positive regulation of iodide transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904214 activation of iodide transmembrane transport|up-regulation of iodide transmembrane transport|up regulation of iodide transmembrane transport|upregulation of iodide transmembrane transport Any process that activates or increases the frequency, rate or extent of iodide transmembrane transport. GO:1904213 negative regulation of iodide transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904213 down-regulation of iodide transmembrane transport|downregulation of iodide transmembrane transport|down regulation of iodide transmembrane transport|inhibition of iodide transmembrane transport Any process that stops, prevents or reduces the frequency, rate or extent of iodide transmembrane transport. GO:1904212 regulation of iodide transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904212 Any process that modulates the frequency, rate or extent of iodide transmembrane transport. GO:1904222 positive regulation of serine C-palmitoyltransferase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904222 activation of serine C-palmitoyltransferase activity|upregulation of 3-oxosphinganine synthetase activity|upregulation of SPT|up regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating|positive regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating|positive regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|up-regulation of 3-oxosphinganine synthetase activity|activation of 3-oxosphinganine synthetase activity|up regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|up regulation of SPT|up regulation of serine C-palmitoyltransferase activity|positive regulation of SPT|activation of acyl-CoA:serine C-2 acyltransferase decarboxylating|activation of SPT|up-regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating|positive regulation of 3-oxosphinganine synthetase activity|upregulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|upregulation of serine C-palmitoyltransferase activity|up regulation of 3-oxosphinganine synthetase activity|up-regulation of SPT|upregulation of acyl-CoA:serine C-2 acyltransferase decarboxylating|up-regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|up-regulation of serine C-palmitoyltransferase activity|activation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity Any process that activates or increases the frequency, rate or extent of serine C-palmitoyltransferase activity. GO:1904221 negative regulation of serine C-palmitoyltransferase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904221 downregulation of acyl-CoA:serine C-2 acyltransferase decarboxylating|down-regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|negative regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|down regulation of SPT|down-regulation of serine C-palmitoyltransferase activity|downregulation of SPT|negative regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating|down-regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating|downregulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|downregulation of serine C-palmitoyltransferase activity|down-regulation of 3-oxosphinganine synthetase activity|negative regulation of 3-oxosphinganine synthetase activity|down-regulation of SPT|down regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|negative regulation of SPT|down regulation of serine C-palmitoyltransferase activity|inhibition of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|inhibition of serine C-palmitoyltransferase activity|inhibition of acyl-CoA:serine C-2 acyltransferase decarboxylating|downregulation of 3-oxosphinganine synthetase activity|down regulation of 3-oxosphinganine synthetase activity|inhibition of SPT|down regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating|inhibition of 3-oxosphinganine synthetase activity Any process that stops, prevents or reduces the frequency, rate or extent of serine C-palmitoyltransferase activity. CHEBI:39437 tocol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39437 GO:1904220 regulation of serine C-palmitoyltransferase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904220 regulation of serine palmitoyltransferase|regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating|regulation of SPT|regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|regulation of 3-oxosphinganine synthetase activity Any process that modulates the frequency, rate or extent of serine C-palmitoyltransferase activity. CHEBI:39436 chromenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39436 CHEBI:39435 cycloheptafuran biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39435 CHEBI:39439 benzoquinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39439 GO:0052461 obsolete modulation by organism of pathogen-associated molecular pattern-induced symbiont innate immunity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052461 modulation by organism of pathogen-associated molecular pattern-induced symbiont innate immunity OBSOLETE. This term was not defined before being made obsolete. GO:0052460 modulation by host of nutrient release from symbiont biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052460 Any process in which an organism modulates the frequency, rate or extent of the release of nutrients from a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052465 obsolete modulation by organism of defense-related symbiont reactive oxygen species production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052465 modulation by organism of defense-related symbiont metabolic burst|modulation by organism of defense-related symbiont active oxygen species production|modulation by organism of defense-related symbiont ROS production|modulation by organism of defense-related symbiont respiratory burst|modulation by organism of defense-related symbiont reactive oxygen intermediate production|modulation by organism of defense-related symbiont reactive oxygen species production|modulation by organism of defense-related symbiont reactive oxidative species production|modulation by organism of defense-related symbiont AOS production|modulation by organism of defense-related symbiont oxidative burst|modulation by organism of defense-related symbiont ROI production OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the production of reactive oxygen species as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:39434 limonoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39434 GO:0052464 obsolete modulation by organism of symbiont programmed cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052464 modulation of symbiont PCD|modulation by organism of symbiont programmed cell death|modulation of symbiont HR|modulation of symbiont hypersensitive response OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of programmed cell death in a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052463 obsolete modulation by organism of symbiont phytoalexin production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052463 modulation by organism of symbiont phytoalexin production OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of production of phytoalexins as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:39432 furochromene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39432 GO:0052462 obsolete modulation by host of symbiont phagocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052462 OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052479 obsolete negative regulation by organism of defense-related symbiont ethylene-mediated signal transduction pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052479 negative regulation by organism of defense-related symbiont ethylene-mediated signal transduction pathway|suppression by organism of defense-related symbiont ethylene-mediated signal transduction pathway OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont ethylene-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052478 obsolete negative regulation by organism of defense-related symbiont cell wall callose deposition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052478 negative regulation by organism of defense-related symbiont cell wall callose deposition OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the deposition of callose by the symbiont in its cell walls, occurring as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052477 obsolete negative regulation by organism of defense-related symbiont callose deposition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052477 suppression by organism of defense-related symbiont callose deposition|negative regulation by organism of defense-related symbiont callose deposition OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of callose deposition performed by the symbiont as part of its defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. PR:000002190 RAC-alpha serine/threonine-protein kinase biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000002190 AKT1|Akt|RAC-PK-alpha|proto-oncogene c-Akt|protein kinase B|thymoma viral proto-oncogene|AKT1 kinase|PKB|RAC An AKT kinase that is a translation product of the human AKT1 gene or a 1:1 ortholog thereof. GO:1904229 regulation of succinate dehydrogenase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904229 regulation of succinate:acceptor oxidoreductase activity|regulation of fumarate dehydrogenase activity|regulation of fumaric hydrogenase activity|regulation of succinic dehydrogenase activity|regulation of fumarate reductase activity|regulation of succinate:(acceptor) oxidoreductase activity|regulation of succinate oxidoreductase activity|regulation of succinic acid dehydrogenase activity|regulation of succinodehydrogenase activity|regulation of succinyl dehydrogenase activity Any process that modulates the frequency, rate or extent of succinate dehydrogenase activity. GO:1904228 positive regulation of glycogen synthase activity, transferring glucose-1-phosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904228 upregulation of glycogen synthase activity, transferring glucose-1-phosphate|activation of glycogen synthase activity, transferring glucose-1-phosphate|up-regulation of glycogen synthase activity, transferring glucose-1-phosphate|up regulation of glycogen synthase activity, transferring glucose-1-phosphate Any process that activates or increases the frequency, rate or extent of glycogen synthase activity, transferring glucose-1-phosphate. GO:1904227 negative regulation of glycogen synthase activity, transferring glucose-1-phosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904227 down-regulation of glycogen synthase activity, transferring glucose-1-phosphate|downregulation of glycogen synthase activity, transferring glucose-1-phosphate|down regulation of glycogen synthase activity, transferring glucose-1-phosphate|inhibition of glycogen synthase activity, transferring glucose-1-phosphate Any process that stops, prevents or reduces the frequency, rate or extent of glycogen synthase activity, transferring glucose-1-phosphate. GO:1904226 regulation of glycogen synthase activity, transferring glucose-1-phosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904226 Any process that modulates the frequency, rate or extent of glycogen synthase activity, transferring glucose-1-phosphate. GO:1904225 positive regulation of glucuronosyltransferase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904225 up regulation of p-nitrophenylglucuronosyltransferase activity|upregulation of UDP-glucuronosyltransferase activity|up regulation of p-phenylphenol glucuronyltransferase activity|up-regulation of bilirubin uridine diphosphoglucuronyltransferase activity|up-regulation of ciramadol UDP-glucuronyltransferase activity|up-regulation of uridine diphosphoglucuronosyltransferase activity|positive regulation of UDPGA transferase activity|up-regulation of UDP glucuronate-estriol glucuronosyltransferase activity|up-regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|activation of p-nitrophenol UDP-glucuronosyltransferase activity|upregulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|positive regulation of UDP glucuronosyltransferase activity|up regulation of bilirubin glucuronyltransferase activity|positive regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|up-regulation of UDPGT activity|up-regulation of pnp-UDPGT activity|positive regulation of p-nitrophenylglucuronosyltransferase activity|positive regulation of p-phenylphenol glucuronyltransferase activity|upregulation of 1-naphthol-UDP-glucuronosyltransferase activity|positive regulation of 4-nitrophenol UDPGT activity|activation of UDPGT activity|up-regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|up regulation of glucuronosyltransferase activity|positive regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|activation of bilirubin UDPGT activity|up regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|positive regulation of 17-OH steroid UDPGT activity|up regulation of UDP glucuronosyltransferase activity|activation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|upregulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|activation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|up-regulation of 4-nitrophenol UDP-glucuronyltransferase activity|upregulation of bilirubin monoglucuronide glucuronyltransferase activity|up regulation of UDPGA transferase activity|upregulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|up-regulation of bilirubin UDP-glucuronosyltransferase activity|activation of UDP-glucuronate-bilirubin glucuronyltransferase activity|upregulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|positive regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|upregulation of UDP-glucuronyltransferase activity|positive regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|up regulation of 4-nitrophenol UDPGT activity|up-regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity|up regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|positive regulation of uridine diphosphate glucuronyltransferase activity|up-regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|up regulation of 17-OH steroid UDPGT activity|up regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|activation of p-nitrophenol UDP-glucuronyltransferase activity|activation of 3-OH androgenic UDPGT activity|up-regulation of uridine diphosphoglucuronyltransferase activity|positive regulation of UDP glucuronyltransferase activity|up-regulation of uridine 5'-diphosphoglucuronyltransferase activity|activation of ciramadol UDP-glucuronyltransferase activity|up regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|positive regulation of p-nitrophenol UDP-glucuronosyltransferase activity|activation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|up-regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|up-regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|positive regulation of bilirubin UDPGT activity|activation of uridine 5'-diphosphoglucuronyltransferase activity|activation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|up regulation of UDP glucuronyltransferase activity|activation of UDP glucuronate-estriol glucuronosyltransferase activity|up regulation of uridine diphosphate glucuronyltransferase activity|up-regulation of UDPGA-glucuronyltransferase activity|upregulation of PNP-UDPGT|upregulation of UDP glucuronic acid transferase activity|activation of p-nitrophenylglucuronosyltransferase activity|activation of pnp-UDPGT activity|positive regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|activation of p-phenylphenol glucuronyltransferase activity|upregulation of estrone UDPglucuronosyltransferase activity|up regulation of p-nitrophenol UDP-glucuronosyltransferase activity|upregulation of UDP glucuronate-estradiol-glucuronosyltransferase activity|activation of UDPGA-glucuronyltransferase activity|up regulation of phenyl-UDP-glucuronosyltransferase activity|upregulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|upregulation of estriol UDPglucuronosyltransferase activity|positive regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity|up-regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|up-regulation of UDP-glucuronosyltransferase activity|up regulation of morphine glucuronyltransferase activity|up-regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|up regulation of bilirubin UDPGT activity|upregulation of bilirubin uridine diphosphoglucuronyltransferase activity|activation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|activation of 4-nitrophenol UDP-glucuronyltransferase activity|up regulation of 1-naphthol glucuronyltransferase activity|activation of UDP-glucuronosyltransferase activity|positive regulation of 3-OH androgenic UDPGT activity|positive regulation of phenyl-UDP-glucuronosyltransferase activity|activation of bilirubin UDP-glucuronosyltransferase activity|activation of p-hydroxybiphenyl UDP glucuronyltransferase activity|upregulation of uridine diphosphoglucuronosyltransferase activity|positive regulation of p-nitrophenol UDP-glucuronyltransferase activity|up-regulation of GT activity|positive regulation of ciramadol UDP-glucuronyltransferase activity|upregulation of bilirubin glucuronyltransferase activity|upregulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|up regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity|up regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|positive regulation of 1-naphthol glucuronyltransferase activity|positive regulation of morphine glucuronyltransferase activity|up regulation of 1-naphthol-UDP-glucuronosyltransferase activity|up-regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|activation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|positive regulation of UDP glucuronate-estriol glucuronosyltransferase activity|upregulation of glucuronosyltransferase activity|up regulation of 3-OH androgenic UDPGT activity|positive regulation of UDPGT activity|up regulation of p-nitrophenol UDP-glucuronyltransferase activity|activation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|up-regulation of bilirubin monoglucuronide glucuronyltransferase activity|positive regulation of pnp-UDPGT activity|up-regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|positive regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|positive regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|upregulation of UDPGA transferase activity|up-regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|up regulation of ciramadol UDP-glucuronyltransferase activity|up-regulation of p-nitrophenylglucuronosyltransferase activity|up-regulation of UDP-glucuronyltransferase activity|up-regulation of p-phenylphenol glucuronyltransferase activity|upregulation of UDP glucuronosyltransferase activity|activation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|up-regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|upregulation of uridine diphosphoglucuronyltransferase activity|upregulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|up regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|positive regulation of 1-naphthol-UDP-glucuronosyltransferase activity|up regulation of UDP glucuronate-estriol glucuronosyltransferase activity|up regulation of UDPGT activity|up regulation of pnp-UDPGT activity|upregulation of 4-nitrophenol UDPGT activity|positive regulation of 4-nitrophenol UDP-glucuronyltransferase activity|activation of UDP-glucuronyltransferase activity|upregulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|positive regulation of bilirubin UDP-glucuronosyltransferase activity|upregulation of 17-OH steroid UDPGT activity|up-regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|activation of phenyl-UDP-glucuronosyltransferase activity|positive regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity|up-regulation of UDP glucuronic acid transferase activity|activation of morphine glucuronyltransferase activity|upregulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|up regulation of 4-nitrophenol UDP-glucuronyltransferase activity|activation of 1-naphthol glucuronyltransferase activity|positive regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|upregulation of uridine diphosphate glucuronyltransferase activity|up regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity|up-regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|up-regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity|activation of UDP glucuronic acid transferase activity|up regulation of PNP-UDPGT|up regulation of bilirubin UDP-glucuronosyltransferase activity|positive regulation of uridine 5'-diphosphoglucuronyltransferase activity|upregulation of UDP glucuronyltransferase activity|up regulation of estriol UDPglucuronosyltransferase activity|positive regulation of UDPGA-glucuronyltransferase activity|upregulation of p-nitrophenol UDP-glucuronosyltransferase activity|activation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|up-regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|activation of bilirubin monoglucuronide glucuronyltransferase activity|activation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|upregulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|up regulation of estrone UDPglucuronosyltransferase activity|upregulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|positive regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|positive regulation of PNP-UDPGT|up regulation of uridine 5'-diphosphoglucuronyltransferase activity|up regulation of bilirubin uridine diphosphoglucuronyltransferase activity|activation of 1-naphthol-UDP-glucuronosyltransferase activity|activation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|upregulation of GT activity|up regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|upregulation of bilirubin UDPGT activity|activation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|up regulation of uridine diphosphoglucuronosyltransferase activity|positive regulation of UDP-glucuronosyltransferase activity|up regulation of UDPGA-glucuronyltransferase activity|positive regulation of estrone UDPglucuronosyltransferase activity|up-regulation of bilirubin glucuronyltransferase activity|up regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|positive regulation of estriol UDPglucuronosyltransferase activity|upregulation of UDP-glucuronate-bilirubin glucuronyltransferase activity|up regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|upregulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|up-regulation of glucuronosyltransferase activity|up-regulation of phenyl-UDP-glucuronosyltransferase activity|positive regulation of bilirubin uridine diphosphoglucuronyltransferase activity|up regulation of UDP-glucuronosyltransferase activity|up-regulation of UDPGA transferase activity|activation of uridine diphosphoglucuronosyltransferase activity|up-regulation of morphine glucuronyltransferase activity|upregulation of p-nitrophenol UDP-glucuronyltransferase activity|upregulation of 3-OH androgenic UDPGT activity|positive regulation of uridine diphosphoglucuronosyltransferase activity|upregulation of p-nitrophenylglucuronosyltransferase activity|up-regulation of UDP glucuronosyltransferase activity|up-regulation of 1-naphthol glucuronyltransferase activity|activation of glucuronosyltransferase activity|upregulation of p-phenylphenol glucuronyltransferase activity|activation of UDP glucuronosyltransferase activity|up-regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|positive regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|upregulation of ciramadol UDP-glucuronyltransferase activity|positive regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|positive regulation of bilirubin monoglucuronide glucuronyltransferase activity|up-regulation of 4-nitrophenol UDPGT activity|activation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|activation of UDP glucuronate-estradiol-glucuronosyltransferase activity|activation of UDPGA transferase activity|upregulation of UDPGT activity|up-regulation of 17-OH steroid UDPGT activity|upregulation of UDP glucuronate-estriol glucuronosyltransferase activity|upregulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|up regulation of uridine diphosphoglucuronyltransferase activity|upregulation of pnp-UDPGT activity|positive regulation of UDP-glucuronyltransferase activity|up regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|up-regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|positive regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|activation of PNP-UDPGT|positive regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|upregulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|activation of estrone UDPglucuronosyltransferase activity|up regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|up-regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|up-regulation of 1-naphthol-UDP-glucuronosyltransferase activity|activation of estriol UDPglucuronosyltransferase activity|up regulation of bilirubin monoglucuronide glucuronyltransferase activity|positive regulation of uridine diphosphoglucuronyltransferase activity|activation of bilirubin uridine diphosphoglucuronyltransferase activity|positive regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|up regulation of UDP-glucuronyltransferase activity|up regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|upregulation of 4-nitrophenol UDP-glucuronyltransferase activity|activation of uridine diphosphoglucuronyltransferase activity|up-regulation of UDP glucuronyltransferase activity|activation of bilirubin glucuronyltransferase activity|up regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|activation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|up-regulation of uridine diphosphate glucuronyltransferase activity|up-regulation of p-nitrophenol UDP-glucuronosyltransferase activity|upregulation of p-hydroxybiphenyl UDP glucuronyltransferase activity|activation of UDP glucuronyltransferase activity|upregulation of bilirubin UDP-glucuronosyltransferase activity|upregulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|positive regulation of UDP glucuronic acid transferase activity|activation of uridine diphosphate glucuronyltransferase activity|up regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|up-regulation of bilirubin UDPGT activity|up regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|activation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|positive regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|positive regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity|activation of 4-nitrophenol UDPGT activity|activation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|upregulation of uridine 5'-diphosphoglucuronyltransferase activity|up regulation of UDP glucuronic acid transferase activity|upregulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|up regulation of GT activity|up regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|up regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity|up-regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity|positive regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|upregulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|upregulation of phenyl-UDP-glucuronosyltransferase activity|upregulation of UDPGA-glucuronyltransferase activity|activation of 17-OH steroid UDPGT activity|positive regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|up-regulation of PNP-UDPGT|up-regulation of 3-OH androgenic UDPGT activity|upregulation of morphine glucuronyltransferase activity|up-regulation of estrone UDPglucuronosyltransferase activity|upregulation of 1-naphthol glucuronyltransferase activity|up-regulation of p-nitrophenol UDP-glucuronyltransferase activity|positive regulation of GT activity|up regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|activation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|up-regulation of estriol UDPglucuronosyltransferase activity|activation of GT activity|positive regulation of bilirubin glucuronyltransferase activity Any process that activates or increases the frequency, rate or extent of glucuronosyltransferase activity. GO:1904224 negative regulation of glucuronosyltransferase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904224 down regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|down regulation of phenyl-UDP-glucuronosyltransferase activity|negative regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|downregulation of UDP glucuronate-estradiol-glucuronosyltransferase activity|downregulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|down regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|inhibition of uridine diphosphoglucuronosyltransferase activity|down-regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|downregulation of UDP glucuronic acid transferase activity|inhibition of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|downregulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|inhibition of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|down regulation of 1-naphthol glucuronyltransferase activity|down-regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|down-regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|negative regulation of p-nitrophenol UDP-glucuronosyltransferase activity|down-regulation of uridine diphosphate glucuronyltransferase activity|down-regulation of UDP glucuronyltransferase activity|negative regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|down regulation of morphine glucuronyltransferase activity|down-regulation of p-nitrophenol UDP-glucuronosyltransferase activity|down regulation of UDP-glucuronyltransferase activity|negative regulation of UDP glucuronyltransferase activity|negative regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|negative regulation of uridine diphosphate glucuronyltransferase activity|negative regulation of bilirubin UDPGT activity|inhibition of UDP-glucuronyltransferase activity|down-regulation of bilirubin UDPGT activity|inhibition of estriol UDPglucuronosyltransferase activity|inhibition of PNP-UDPGT|downregulation of bilirubin glucuronyltransferase activity|inhibition of estrone UDPglucuronosyltransferase activity|down-regulation of GT activity|down regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|negative regulation of GT activity|down-regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|negative regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity|downregulation of phenyl-UDP-glucuronosyltransferase activity|down regulation of 1-naphthol-UDP-glucuronosyltransferase activity|down-regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity|inhibition of uridine diphosphoglucuronyltransferase activity|inhibition of bilirubin uridine diphosphoglucuronyltransferase activity|down regulation of UDP glucuronic acid transferase activity|negative regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|down regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity|down regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|downregulation of glucuronosyltransferase activity|down-regulation of p-phenylphenol glucuronyltransferase activity|down-regulation of 3-OH androgenic UDPGT activity|inhibition of UDP glucuronic acid transferase activity|downregulation of 1-naphthol glucuronyltransferase activity|down-regulation of p-nitrophenol UDP-glucuronyltransferase activity|negative regulation of p-nitrophenylglucuronosyltransferase activity|negative regulation of 3-OH androgenic UDPGT activity|negative regulation of p-phenylphenol glucuronyltransferase activity|negative regulation of p-nitrophenol UDP-glucuronyltransferase activity|downregulation of morphine glucuronyltransferase activity|down-regulation of p-nitrophenylglucuronosyltransferase activity|downregulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|downregulation of 4-nitrophenol UDPGT activity|downregulation of UDP glucuronosyltransferase activity|negative regulation of ciramadol UDP-glucuronyltransferase activity|inhibition of bilirubin monoglucuronide glucuronyltransferase activity|inhibition of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|downregulation of UDPGA transferase activity|down-regulation of ciramadol UDP-glucuronyltransferase activity|inhibition of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|negative regulation of UDP glucuronate-estriol glucuronosyltransferase activity|negative regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|negative regulation of pnp-UDPGT activity|down-regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|inhibition of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|down-regulation of pnp-UDPGT activity|down-regulation of UDP glucuronate-estriol glucuronosyltransferase activity|downregulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|inhibition of 4-methylumbelliferone UDP-glucuronosyltransferase activity|negative regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|down-regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|downregulation of 17-OH steroid UDPGT activity|down regulation of bilirubin glucuronyltransferase activity|down-regulation of UDPGT activity|negative regulation of UDPGT activity|downregulation of 1-naphthol-UDP-glucuronosyltransferase activity|down regulation of glucuronosyltransferase activity|inhibition of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|downregulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|down-regulation of 4-nitrophenol UDP-glucuronyltransferase activity|inhibition of GT activity|negative regulation of 4-nitrophenol UDP-glucuronyltransferase activity|downregulation of uridine diphosphate glucuronyltransferase activity|downregulation of UDP glucuronyltransferase activity|down-regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|down-regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity|negative regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity|down regulation of PNP-UDPGT|down-regulation of bilirubin UDP-glucuronosyltransferase activity|down regulation of estrone UDPglucuronosyltransferase activity|downregulation of p-nitrophenol UDP-glucuronosyltransferase activity|down regulation of UDPGA transferase activity|down regulation of UDP glucuronosyltransferase activity|negative regulation of bilirubin UDP-glucuronosyltransferase activity|inhibition of glucuronosyltransferase activity|negative regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|down regulation of estriol UDPglucuronosyltransferase activity|down regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|down regulation of 4-nitrophenol UDPGT activity|inhibition of UDPGA transferase activity|down regulation of bilirubin uridine diphosphoglucuronyltransferase activity|inhibition of UDP glucuronosyltransferase activity|downregulation of bilirubin UDPGT activity|inhibition of UDP glucuronate-estradiol-glucuronosyltransferase activity|down regulation of 17-OH steroid UDPGT activity|inhibition of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|negative regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|down-regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|negative regulation of uridine 5'-diphosphoglucuronyltransferase activity|down-regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|negative regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|down regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|down regulation of uridine diphosphoglucuronosyltransferase activity|negative regulation of phenyl-UDP-glucuronosyltransferase activity|down-regulation of uridine 5'-diphosphoglucuronyltransferase activity|downregulation of UDP-glucuronate-bilirubin glucuronyltransferase activity|down-regulation of phenyl-UDP-glucuronosyltransferase activity|down regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|inhibition of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|inhibition of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|down regulation of uridine diphosphate glucuronyltransferase activity|down-regulation of UDPGA-glucuronyltransferase activity|inhibition of bilirubin glucuronyltransferase activity|down-regulation of morphine glucuronyltransferase activity|downregulation of 3-OH androgenic UDPGT activity|downregulation of p-nitrophenol UDP-glucuronyltransferase activity|downregulation of estrone UDPglucuronosyltransferase activity|down regulation of p-nitrophenol UDP-glucuronosyltransferase activity|down-regulation of 1-naphthol glucuronyltransferase activity|downregulation of PNP-UDPGT|negative regulation of morphine glucuronyltransferase activity|negative regulation of UDPGA-glucuronyltransferase activity|inhibition of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|downregulation of estriol UDPglucuronosyltransferase activity|down regulation of UDP glucuronyltransferase activity|negative regulation of 1-naphthol glucuronyltransferase activity|downregulation of ciramadol UDP-glucuronyltransferase activity|inhibition of UDP glucuronyltransferase activity|downregulation of bilirubin uridine diphosphoglucuronyltransferase activity|down regulation of bilirubin UDPGT activity|inhibition of uridine diphosphate glucuronyltransferase activity|downregulation of pnp-UDPGT activity|inhibition of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|down-regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|negative regulation of UDP-glucuronosyltransferase activity|down regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|downregulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|negative regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|down-regulation of UDP-glucuronosyltransferase activity|downregulation of UDP glucuronate-estriol glucuronosyltransferase activity|inhibition of p-nitrophenylglucuronosyltransferase activity|downregulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|inhibition of p-phenylphenol glucuronyltransferase activity|inhibition of 4-nitrophenol UDPGT activity|inhibition of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|downregulation of UDPGT activity|down-regulation of 1-naphthol-UDP-glucuronosyltransferase activity|downregulation of uridine diphosphoglucuronosyltransferase activity|down regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity|down regulation of uridine diphosphoglucuronyltransferase activity|negative regulation of 1-naphthol-UDP-glucuronosyltransferase activity|down regulation of 3-OH androgenic UDPGT activity|negative regulation of bilirubin monoglucuronide glucuronyltransferase activity|downregulation of 4-nitrophenol UDP-glucuronyltransferase activity|negative regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|down regulation of p-nitrophenol UDP-glucuronyltransferase activity|down-regulation of bilirubin monoglucuronide glucuronyltransferase activity|down-regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|inhibition of 17-OH steroid UDPGT activity|inhibition of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|down regulation of ciramadol UDP-glucuronyltransferase activity|negative regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|down-regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|negative regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|downregulation of p-hydroxybiphenyl UDP glucuronyltransferase activity|down-regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|downregulation of bilirubin UDP-glucuronosyltransferase activity|down regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|down regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|down-regulation of UDP-glucuronyltransferase activity|negative regulation of UDP-glucuronyltransferase activity|downregulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|down regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|down regulation of pnp-UDPGT activity|down regulation of UDP glucuronate-estriol glucuronosyltransferase activity|downregulation of uridine diphosphoglucuronyltransferase activity|downregulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|inhibition of p-nitrophenol UDP-glucuronosyltransferase activity|down regulation of UDPGT activity|downregulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|inhibition of bilirubin UDPGT activity|downregulation of uridine 5'-diphosphoglucuronyltransferase activity|down regulation of 4-nitrophenol UDP-glucuronyltransferase activity|down regulation of GT activity|inhibition of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|inhibition of UDPGT activity|down-regulation of PNP-UDPGT|down-regulation of estrone UDPglucuronosyltransferase activity|down regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity|down regulation of bilirubin UDP-glucuronosyltransferase activity|negative regulation of PNP-UDPGT|down-regulation of UDP glucuronic acid transferase activity|negative regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity|negative regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|down-regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity|down-regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|negative regulation of estriol UDPglucuronosyltransferase activity|down-regulation of estriol UDPglucuronosyltransferase activity|downregulation of UDPGA-glucuronyltransferase activity|down regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|negative regulation of UDP glucuronic acid transferase activity|negative regulation of estrone UDPglucuronosyltransferase activity|downregulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|downregulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|down regulation of p-nitrophenylglucuronosyltransferase activity|negative regulation of bilirubin uridine diphosphoglucuronyltransferase activity|inhibition of UDP-glucuronate-bilirubin glucuronyltransferase activity|down regulation of p-phenylphenol glucuronyltransferase activity|down-regulation of bilirubin uridine diphosphoglucuronyltransferase activity|inhibition of p-nitrophenol UDP-glucuronyltransferase activity|down regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|inhibition of phenyl-UDP-glucuronosyltransferase activity|downregulation of UDP-glucuronosyltransferase activity|inhibition of 3-OH androgenic UDPGT activity|downregulation of GT activity|negative regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|inhibition of 1-naphthol glucuronyltransferase activity|down-regulation of uridine diphosphoglucuronosyltransferase activity|negative regulation of uridine diphosphoglucuronosyltransferase activity|down regulation of uridine 5'-diphosphoglucuronyltransferase activity|down-regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|inhibition of morphine glucuronyltransferase activity|down-regulation of bilirubin glucuronyltransferase activity|inhibition of ciramadol UDP-glucuronyltransferase activity|negative regulation of bilirubin glucuronyltransferase activity|down regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|down regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|downregulation of bilirubin monoglucuronide glucuronyltransferase activity|inhibition of uridine 5'-diphosphoglucuronyltransferase activity|downregulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|inhibition of UDP glucuronate-estriol glucuronosyltransferase activity|downregulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|down regulation of UDPGA-glucuronyltransferase activity|inhibition of pnp-UDPGT activity|inhibition of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|downregulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|inhibition of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|downregulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|inhibition of UDPGA-glucuronyltransferase activity|downregulation of p-nitrophenylglucuronosyltransferase activity|downregulation of p-phenylphenol glucuronyltransferase activity|down-regulation of glucuronosyltransferase activity|down-regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|down regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|down-regulation of UDPGA transferase activity|inhibition of 4-nitrophenol UDP-glucuronyltransferase activity|down-regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|negative regulation of UDP glucuronosyltransferase activity|inhibition of 1-naphthol-UDP-glucuronosyltransferase activity|negative regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|negative regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|down-regulation of 4-nitrophenol UDPGT activity|down-regulation of UDP glucuronosyltransferase activity|negative regulation of 4-nitrophenol UDPGT activity|negative regulation of UDPGA transferase activity|down regulation of UDP-glucuronosyltransferase activity|downregulation of UDP-glucuronyltransferase activity|down-regulation of uridine diphosphoglucuronyltransferase activity|downregulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|down-regulation of 17-OH steroid UDPGT activity|negative regulation of uridine diphosphoglucuronyltransferase activity|inhibition of UDP-glucuronosyltransferase activity|negative regulation of 17-OH steroid UDPGT activity|inhibition of bilirubin UDP-glucuronosyltransferase activity|inhibition of p-hydroxybiphenyl UDP glucuronyltransferase activity|down regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|down regulation of bilirubin monoglucuronide glucuronyltransferase activity Any process that stops, prevents or reduces the frequency, rate or extent of glucuronosyltransferase activity. GO:1904223 regulation of glucuronosyltransferase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904223 regulation of UDP glucuronic acid transferase activity|regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity|regulation of phenyl-UDP-glucuronosyltransferase activity|regulation of 1-naphthol glucuronyltransferase activity|regulation of morphine glucuronyltransferase activity|regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|regulation of bilirubin glucuronyltransferase activity|regulation of 1-naphthol-UDP-glucuronosyltransferase activity|regulation of UDPGA transferase activity|regulation of UDP glucuronosyltransferase activity|regulation of 4-nitrophenol UDPGT activity|regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|regulation of 17-OH steroid UDPGT activity|regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|regulation of PNP-UDPGT|regulation of UDP glucuronyltransferase activity|regulation of uridine diphosphate glucuronyltransferase activity|regulation of estrone UDPglucuronosyltransferase activity|regulation of p-nitrophenol UDP-glucuronosyltransferase activity|regulation of estriol UDPglucuronosyltransferase activity|regulation of bilirubin UDPGT activity|regulation of bilirubin uridine diphosphoglucuronyltransferase activity|regulation of uridine diphosphoglucuronosyltransferase activity|regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity|regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|regulation of 3-OH androgenic UDPGT activity|regulation of p-nitrophenol UDP-glucuronyltransferase activity|regulation of ciramadol UDP-glucuronyltransferase activity|regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|regulation of UDPGT activity|regulation of UDP glucuronate-estriol glucuronosyltransferase activity|regulation of uridine diphosphoglucuronyltransferase activity|regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|regulation of pnp-UDPGT activity|regulation of 4-nitrophenol UDP-glucuronyltransferase activity|regulation of bilirubin UDP-glucuronosyltransferase activity|regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity|regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|regulation of GT activity|regulation of uridine 5'-diphosphoglucuronyltransferase activity|regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|regulation of UDPGA-glucuronyltransferase activity|regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|regulation of UDP-glucuronosyltransferase activity|regulation of p-phenylphenol glucuronyltransferase activity|regulation of p-nitrophenylglucuronosyltransferase activity|regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|regulation of bilirubin monoglucuronide glucuronyltransferase activity|regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|regulation of UDP-glucuronyltransferase activity|regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity Any process that modulates the frequency, rate or extent of glucuronosyltransferase activity. GO:1904233 negative regulation of aconitate hydratase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904233 downregulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|down regulation of citrate(isocitrate) hydro-lyase activity|inhibition of citrate(isocitrate) hydro-lyase activity|down-regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|negative regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|down-regulation of cis-aconitase activity|down-regulation of aconitate hydratase activity|negative regulation of aconitase activity|negative regulation of cis-aconitase activity|down-regulation of aconitase activity|inhibition of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|down-regulation of citrate(isocitrate) hydro-lyase activity|negative regulation of citrate(isocitrate) hydro-lyase activity|downregulation of aconitate hydratase activity|downregulation of aconitase activity|downregulation of cis-aconitase activity|down regulation of cis-aconitase activity|down regulation of aconitase activity|down regulation of aconitate hydratase activity|down regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|inhibition of aconitase activity|inhibition of aconitate hydratase activity|inhibition of cis-aconitase activity|downregulation of citrate(isocitrate) hydro-lyase activity Any process that stops, prevents or reduces the frequency, rate or extent of aconitate hydratase activity. CHEBI:39449 2-undecenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39449 CHEBI:39448 undecenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39448 GO:1904232 regulation of aconitate hydratase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904232 regulation of citrate(isocitrate) hydro-lyase activity|regulation of citrate hydro-lyase activity|regulation of cis-aconitase activity|regulation of aconitase activity|regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming) Any process that modulates the frequency, rate or extent of aconitate hydratase activity. GO:1904231 positive regulation of succinate dehydrogenase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904231 positive regulation of fumarate reductase activity|positive regulation of succinate:acceptor oxidoreductase activity|up regulation of succinate oxidoreductase activity|upregulation of succinic acid dehydrogenase activity|upregulation of succinate:(acceptor) oxidoreductase activity|activation of succinate oxidoreductase activity|up regulation of succinate:acceptor oxidoreductase activity|positive regulation of succinate oxidoreductase activity|positive regulation of fumaric hydrogenase activity|up regulation of succinodehydrogenase activity|upregulation of fumarate dehydrogenase activity|activation of succinodehydrogenase activity|up regulation of succinyl dehydrogenase activity|up regulation of fumaric hydrogenase activity|positive regulation of succinodehydrogenase activity|up regulation of succinate dehydrogenase activity|activation of succinyl dehydrogenase activity|up-regulation of fumarate reductase activity|positive regulation of succinyl dehydrogenase activity|activation of succinate:(acceptor) oxidoreductase activity|up-regulation of succinic acid dehydrogenase activity|up-regulation of succinate:(acceptor) oxidoreductase activity|activation of succinic acid dehydrogenase activity|upregulation of succinate:acceptor oxidoreductase activity|up-regulation of succinate oxidoreductase activity|up regulation of fumarate dehydrogenase activity|activation of fumarate dehydrogenase activity|upregulation of fumaric hydrogenase activity|up-regulation of succinodehydrogenase activity|upregulation of succinate dehydrogenase activity|upregulation of fumarate reductase activity|positive regulation of fumarate dehydrogenase activity|up-regulation of succinyl dehydrogenase activity|positive regulation of succinate:(acceptor) oxidoreductase activity|up-regulation of succinate:acceptor oxidoreductase activity|positive regulation of succinic acid dehydrogenase activity|activation of succinate:acceptor oxidoreductase activity|up regulation of succinate:(acceptor) oxidoreductase activity|up regulation of succinic acid dehydrogenase activity|upregulation of succinate oxidoreductase activity|up-regulation of fumaric hydrogenase activity|activation of fumaric hydrogenase activity|activation of succinate dehydrogenase activity|upregulation of succinodehydrogenase activity|up-regulation of succinate dehydrogenase activity|up regulation of fumarate reductase activity|up-regulation of fumarate dehydrogenase activity|activation of fumarate reductase activity|upregulation of succinyl dehydrogenase activity Any process that activates or increases the frequency, rate or extent of succinate dehydrogenase activity. CHEBI:39447 pyrimidines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39447 GO:1904230 negative regulation of succinate dehydrogenase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904230 down regulation of succinic acid dehydrogenase activity|down regulation of succinyl dehydrogenase activity|down regulation of succinate:(acceptor) oxidoreductase activity|downregulation of succinate oxidoreductase activity|negative regulation of fumaric hydrogenase activity|down-regulation of fumaric hydrogenase activity|downregulation of succinodehydrogenase activity|down-regulation of succinate dehydrogenase activity|negative regulation of fumarate reductase activity|inhibition of succinic acid dehydrogenase activity|inhibition of succinate:(acceptor) oxidoreductase activity|down-regulation of fumarate reductase activity|downregulation of succinyl dehydrogenase activity|downregulation of succinate:acceptor oxidoreductase activity|inhibition of fumarate reductase activity|negative regulation of succinate oxidoreductase activity|down regulation of fumarate dehydrogenase activity|down-regulation of succinate oxidoreductase activity|downregulation of fumaric hydrogenase activity|down-regulation of succinodehydrogenase activity|downregulation of succinate dehydrogenase activity|negative regulation of succinodehydrogenase activity|down regulation of succinate:acceptor oxidoreductase activity|down-regulation of succinyl dehydrogenase activity|inhibition of succinate:acceptor oxidoreductase activity|negative regulation of succinyl dehydrogenase activity|downregulation of fumarate dehydrogenase activity|down regulation of fumaric hydrogenase activity|down regulation of succinate dehydrogenase activity|inhibition of succinate oxidoreductase activity|inhibition of fumaric hydrogenase activity|inhibition of succinate dehydrogenase activity|inhibition of succinodehydrogenase activity|down-regulation of succinic acid dehydrogenase activity|down-regulation of succinate:(acceptor) oxidoreductase activity|negative regulation of succinic acid dehydrogenase activity|negative regulation of succinate:(acceptor) oxidoreductase activity|inhibition of succinyl dehydrogenase activity|down regulation of fumarate reductase activity|down-regulation of fumarate dehydrogenase activity|negative regulation of fumarate dehydrogenase activity|downregulation of fumarate reductase activity|downregulation of succinate:(acceptor) oxidoreductase activity|downregulation of succinic acid dehydrogenase activity|down regulation of succinate oxidoreductase activity|inhibition of fumarate dehydrogenase activity|negative regulation of succinate:acceptor oxidoreductase activity|down regulation of succinodehydrogenase activity|down-regulation of succinate:acceptor oxidoreductase activity Any process that stops, prevents or reduces the frequency, rate or extent of succinate dehydrogenase activity. CHEBI:39446 pyrimidine ribonucleosides biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39446 CHEBI:15499 4-coumaroyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15499 GO:0052472 modulation by host of symbiont transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052472 Any process in which an organism modulates the frequency, rate or extent of its symbiont's transcription. CHEBI:15496 4-aminobutanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15496 GO:0052471 obsolete modulation by organism of systemic acquired resistance in symbiont biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052471 modulation by organism of systemic acquired resistance in symbiont OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of systemic acquired resistance in the symbiont organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:15495 4,8,12-trimethyltridecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15495 GO:0052470 obsolete modulation by host of symbiont signal transduction pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052470 OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of the symbiont signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:15498 4-chlorobenzoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15498 CHEBI:15497 trans-4-carboxybut-2-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15497 GO:0052476 obsolete negative regulation by organism of defense-related symbiont MAP kinase-mediated signal transduction pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052476 negative regulation by organism of defense-related symbiont MAPK-mediated signal transduction pathway|negative regulation by organism of defense-related symbiont mitogen-activated protein kinase-mediated signal transduction pathway|negative regulation by organism of defense-related symbiont MAP kinase-mediated signal transduction pathway|suppression by organism of defense-related symbiont MAP kinase-mediated signal transduction pathway OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont MAP kinase-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:15492 3-oxopimeloyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15492 GO:0052475 obsolete negative regulation by organism of symbiont cell-mediated immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052475 negative regulation by organism of symbiont cell-based immune response|negative regulation by organism of symbiont cell-mediated immune response OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the cell mediated immune response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:15491 3-oxopalmitoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15491 GO:0052474 obsolete negative regulation by organism of symbiont T-cell mediated immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052474 negative regulation by organism of symbiont T-cell mediated immune response OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the T-cell mediated immune response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:15494 3alpha,7alpha-dihydroxy-5beta-cholestan-26-oyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15494 GO:0052473 obsolete negative regulation by organism of symbiont B-cell mediated immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052473 negative regulation by organism of symbiont B-cell mediated immune response OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the B-cell mediated immune response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:39442 fluorescent probe biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39442 CHEBI:15493 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15493 GO:0052489 negative regulation by host of symbiont programmed cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052489 inhibition of symbiont programmed cell death|downregulation by host of symbiont programmed cell death|down regulation by host of symbiont programmed cell death|inhibition by host of symbiont programmed cell death|down-regulation by host of symbiont programmed cell death Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052488 obsolete negative regulation by organism of pathogen-associated molecular pattern-induced symbiont innate immunity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052488 suppression of general elicitor induced symbiont innate immunity|suppression of PAMP-induced symbiont innate immunity|suppression of pathogen-associated molecular pattern-induced symbiont innate immunity|suppression of MAMP-induced symbiont innate immunity|negative regulation by organism of pathogen-associated molecular pattern-induced symbiont innate immunity|suppression of PAMP induced symbiont innate immunity|suppression of MAMP induced symbiont innate immunity|suppression of general elicitor-induced symbiont innate immunity OBSOLETE. This term was not defined before being made obsolete. GO:1904239 regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904239 regulation of VCP-NPL4-UFD1 AAA ATPase complex formation|regulation of p97-Ufd1-Npl4 complex assembly|regulation of p97-Ufd1-Npl4 complex formation|regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation Any process that modulates the frequency, rate or extent of VCP-NPL4-UFD1 AAA ATPase complex assembly. CHEBI:40410 N-acetylglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_40410 GO:1904238 pericyte cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904238 The process in which a relatively unspecialized cell acquires the specialized features of a pericyte cell. GO:1904237 positive regulation of substrate-dependent cell migration, cell attachment to substrate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904237 up-regulation of substrate-bound cell migration, cell attachment to substrate|up-regulation of substrate-dependent cell migration, cell attachment to substrate|activation of substrate-bound cell migration, cell attachment to substrate|activation of substrate-dependent cell migration, cell attachment to substrate|positive regulation of substrate-bound cell migration, cell attachment to substrate|up regulation of substrate-bound cell migration, cell attachment to substrate|up regulation of substrate-dependent cell migration, cell attachment to substrate|upregulation of substrate-bound cell migration, cell attachment to substrate|upregulation of substrate-dependent cell migration, cell attachment to substrate Any process that activates or increases the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate. GO:1904236 negative regulation of substrate-dependent cell migration, cell attachment to substrate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904236 down-regulation of substrate-bound cell migration, cell attachment to substrate|negative regulation of substrate-bound cell migration, cell attachment to substrate|down-regulation of substrate-dependent cell migration, cell attachment to substrate|downregulation of substrate-bound cell migration, cell attachment to substrate|downregulation of substrate-dependent cell migration, cell attachment to substrate|down regulation of substrate-bound cell migration, cell attachment to substrate|inhibition of substrate-bound cell migration, cell attachment to substrate|down regulation of substrate-dependent cell migration, cell attachment to substrate|inhibition of substrate-dependent cell migration, cell attachment to substrate Any process that stops, prevents or reduces the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate. GO:1904235 regulation of substrate-dependent cell migration, cell attachment to substrate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904235 regulation of substrate-bound cell migration, cell attachment to substrate Any process that modulates the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate. GO:1904234 positive regulation of aconitate hydratase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904234 up regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|positive regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|activation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|upregulation of citrate(isocitrate) hydro-lyase activity|up-regulation of cis-aconitase activity|up-regulation of aconitase activity|up-regulation of aconitate hydratase activity|activation of cis-aconitase activity|activation of aconitase activity|activation of aconitate hydratase activity|up-regulation of citrate(isocitrate) hydro-lyase activity|up-regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|activation of citrate(isocitrate) hydro-lyase activity|positive regulation of aconitase activity|positive regulation of cis-aconitase activity|up regulation of cis-aconitase activity|up regulation of aconitate hydratase activity|up regulation of aconitase activity|upregulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|positive regulation of citrate(isocitrate) hydro-lyase activity|up regulation of citrate(isocitrate) hydro-lyase activity|upregulation of cis-aconitase activity|upregulation of aconitate hydratase activity|upregulation of aconitase activity Any process that activates or increases the frequency, rate or extent of aconitate hydratase activity. GO:1904244 positive regulation of pancreatic trypsinogen secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904244 upregulation of pancreatic trypsinogen release|up regulation of pancreatic trypsinogen secretion|up-regulation of pancreatic trypsinogen release|activation of pancreatic trypsinogen release|upregulation of pancreatic trypsinogen secretion|positive regulation of pancreatic trypsinogen release|up regulation of pancreatic trypsinogen release|up-regulation of pancreatic trypsinogen secretion|activation of pancreatic trypsinogen secretion Any process that activates or increases the frequency, rate or extent of pancreatic trypsinogen secretion. CHEBI:15449 (2S,3S)-3-hydroxy-2-methylbutanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15449 CHEBI:15448 (1-hydroxycyclohexyl)acetyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15448 GO:1904243 negative regulation of pancreatic trypsinogen secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904243 down regulation of pancreatic trypsinogen release|inhibition of pancreatic trypsinogen release|down-regulation of pancreatic trypsinogen secretion|downregulation of pancreatic trypsinogen secretion|down regulation of pancreatic trypsinogen secretion|inhibition of pancreatic trypsinogen secretion|down-regulation of pancreatic trypsinogen release|negative regulation of pancreatic trypsinogen release|downregulation of pancreatic trypsinogen release Any process that stops, prevents or reduces the frequency, rate or extent of pancreatic trypsinogen secretion. GO:1904242 regulation of pancreatic trypsinogen secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904242 regulation of pancreatic trypsinogen release Any process that modulates the frequency, rate or extent of pancreatic trypsinogen secretion. GO:1904241 positive regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904241 activation of p97-Ufd1-Npl4 complex formation|activation of p97-Ufd1-Npl4 complex assembly|up-regulation of p97-Ufd1-Npl4 complex assembly|positive regulation of p97-Ufd1-Npl4 complex formation|up regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly|activation of VCP-NPL4-UFD1 AAA ATPase complex assembly|upregulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|up regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|positive regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|positive regulation of VCP-NPL4-UFD1 AAA ATPase complex formation|up regulation of VCP-NPL4-UFD1 AAA ATPase complex formation|up-regulation of p97-Ufd1-Npl4 complex formation|positive regulation of p97-Ufd1-Npl4 complex assembly|activation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|up regulation of p97-Ufd1-Npl4 complex assembly|up-regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|up-regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly|up-regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|activation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|upregulation of p97-Ufd1-Npl4 complex formation|upregulation of VCP-NPL4-UFD1 AAA ATPase complex formation|upregulation of p97-Ufd1-Npl4 complex assembly|upregulation of VCP-NPL4-UFD1 AAA ATPase complex assembly|positive regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|up regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|upregulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|up-regulation of VCP-NPL4-UFD1 AAA ATPase complex formation|activation of VCP-NPL4-UFD1 AAA ATPase complex formation|up regulation of p97-Ufd1-Npl4 complex formation Any process that activates or increases the frequency, rate or extent of VCP-NPL4-UFD1 AAA ATPase complex assembly. GO:1904240 negative regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904240 down regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|downregulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|down-regulation of p97-Ufd1-Npl4 complex formation|down-regulation of VCP-NPL4-UFD1 AAA ATPase complex formation|negative regulation of p97-Ufd1-Npl4 complex formation|negative regulation of VCP-NPL4-UFD1 AAA ATPase complex formation|down-regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly|down-regulation of p97-Ufd1-Npl4 complex assembly|negative regulation of p97-Ufd1-Npl4 complex assembly|inhibition of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|inhibition of p97-Ufd1-Npl4 complex formation|negative regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|down-regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|downregulation of VCP-NPL4-UFD1 AAA ATPase complex formation|inhibition of VCP-NPL4-UFD1 AAA ATPase complex assembly|downregulation of p97-Ufd1-Npl4 complex assembly|down regulation of VCP-NPL4-UFD1 AAA ATPase complex formation|inhibition of VCP-NPL4-UFD1 AAA ATPase complex formation|down regulation of p97-Ufd1-Npl4 complex assembly|negative regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|down-regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|inhibition of p97-Ufd1-Npl4 complex assembly|down regulation of p97-Ufd1-Npl4 complex formation|inhibition of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|down regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly|downregulation of p97-Ufd1-Npl4 complex formation|downregulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|downregulation of VCP-NPL4-UFD1 AAA ATPase complex assembly|down regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation Any process that stops, prevents or reduces the frequency, rate or extent of VCP-NPL4-UFD1 AAA ATPase complex assembly. CHEBI:15444 (1->4)-alpha-D-glucan biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15444 CHEBI:15447 (1->4)-beta-D-xylan biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15447 CHEBI:39418 straight-chain saturated fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39418 CHEBI:39417 branched-chain saturated fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39417 CHEBI:15446 [(1->4)-alpha-D-galacturonosyl]n biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15446 CHEBI:15441 (S)-2,3-epoxysqualene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15441 GO:0052483 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052483 GO:0052482 defense response by cell wall thickening biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052482 cell wall thickening during defense response A type of cell wall modification, in which the cell wall is reinforced and made thicker, that occurs as part of the defense response of an organism. CHEBI:15440 squalene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15440 GO:0052481 obsolete negative regulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052481 negative modulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway|negative regulation by organism of defense-related symbiont SA-mediated signal transduction pathway|negative regulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway|negative modulation by organism of defense-related symbiont SA-mediated signal transduction pathway OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont salicylic acid-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:15443 inulin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15443 GO:0052480 obsolete negative regulation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052480 negative regulation by organism of defense-related symbiont JA-mediated signal transduction pathway|negative regulation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont jasmonic acid-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:15442 presqualene diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15442 GO:0052487 obsolete negative regulation by organism of symbiont jasmonic acid-mediated defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052487 suppression by organism of symbiont JA-mediated defense response|negative regulation by organism of symbiont jasmonic acid-mediated defense response OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the jasmonic acid-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:39412 bridged diphenyl acaricide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39412 GO:0052486 obsolete negative regulation by organism of symbiont innate immunity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052486 negative regulation by organism of symbiont innate immunity|negative regulation of symbiont innate immune response OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the innate immune response of the symbiont organism, the symbiont's first line of defense against infection. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052485 obsolete negative regulation by organism of symbiont inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052485 negative regulation by organism of symbiont inflammatory response OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the inflammatory response of a symbiont organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052484 obsolete negative regulation by organism of symbiont ethylene-mediated defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052484 suppression by organism of symbiont ethylene-mediated defense response|negative regulation by organism of symbiont ethylene-mediated defense response OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the ethylene-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052499 obsolete pathogen-associated molecular pattern dependent modulation by organism of symbiont innate immunity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052499 pathogen-associated molecular pattern dependent modulation by organism of symbiont innate immunity OBSOLETE. This term was not defined before being made obsolete. GO:1904249 negative regulation of age-related resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904249 down-regulation of ARR|negative regulation of ARR|inhibition of flowering-induced resistance|down regulation of adult seedling resistance|negative regulation of senescence-induced resistance|down-regulation of mature seedling resistance|down-regulation of senescence-induced resistance|negative regulation of mature seedling resistance|downregulation of adult seedling resistance|inhibition of ARR|down-regulation of age-related resistance|negative regulation of flowering-induced resistance|down-regulation of flowering-induced resistance|downregulation of mature seedling resistance|down-regulation of adult seedling resistance|negative regulation of adult seedling resistance|inhibition of senescence-induced resistance|downregulation of age-related resistance|down regulation of ARR|down regulation of mature seedling resistance|down regulation of age-related resistance|downregulation of flowering-induced resistance|downregulation of ARR|inhibition of age-related resistance|down regulation of senescence-induced resistance|down regulation of flowering-induced resistance|inhibition of mature seedling resistance|inhibition of adult seedling resistance|downregulation of senescence-induced resistance Any process that stops, prevents or reduces the extent of age-related resistance. GO:1904248 regulation of age-related resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904248 regulation of adult seedling resistance|regulation of developmental resistance|regulation of mature seedling resistance|regulation of ontogenic resistance|regulation of ARR|regulation of flowering-induced resistance|regulation of senescence-induced resistance Any process that modulates the extent of age-related resistance. GO:1904247 positive regulation of polynucleotide adenylyltransferase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904247 up regulation of terminal riboadenylate transferase activity|positive regulation of poly-A polymerase activity|activation of polynucleotide adenylyltransferase activity|upregulation of polyadenylate polymerase activity|up regulation of poly-A polymerase activity|activation of terminal riboadenylate transferase activity|positive regulation of RNA formation factors, PF1|upregulation of poly(A) hydrolase activity|positive regulation of terminal riboadenylate transferase activity|upregulation of poly(A) polymerase activity|upregulation of polyadenylate synthetase activity|up regulation of RNA formation factors, PF1|up-regulation of RNA adenylating enzyme activity|upregulation of ATP-polynucleotide adenylyltransferase activity|positive regulation of ATP:polynucleotidylexotransferase activity|upregulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|up regulation of polyadenylate nucleotidyltransferase activity|positive regulation of AMP polynucleotidylexotransferase activity|upregulation of poly(A) synthetase activity|upregulation of polyadenylic polymerase activity|up-regulation of polyadenylic acid polymerase activity|up regulation of ATP:polynucleotidylexotransferase activity|up regulation of NTP polymerase activity|activation of polyadenylate nucleotidyltransferase activity|positive regulation of polyadenylate nucleotidyltransferase activity|up regulation of AMP polynucleotidylexotransferase activity|up-regulation of ATP:polynucleotide adenylyltransferase activity|activation of NTP polymerase activity|positive regulation of NTP polymerase activity|up regulation of polyadenylate polymerase activity|up-regulation of poly(A) hydrolase activity|upregulation of poly-A polymerase activity|up-regulation of polynucleotide adenylyltransferase activity|activation of poly(A) hydrolase activity|positive regulation of polyadenylate polymerase activity|up-regulation of terminal riboadenylate transferase activity|activation of polyadenylate polymerase activity|upregulation of RNA formation factors, PF1|up regulation of polyadenylate synthetase activity|up regulation of poly(A) polymerase activity|upregulation of RNA adenylating enzyme activity|up-regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|up regulation of ATP-polynucleotide adenylyltransferase activity|up-regulation of polyadenylic polymerase activity|positive regulation of polyadenylate synthetase activity|activation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|activation of poly(A) polymerase activity|positive regulation of poly(A) polymerase activity|activation of polyadenylate synthetase activity|upregulation of polyadenylic acid polymerase activity|positive regulation of ATP-polynucleotide adenylyltransferase activity|up regulation of poly(A) synthetase activity|activation of polyadenylic polymerase activity|activation of ATP-polynucleotide adenylyltransferase activity|upregulation of ATP:polynucleotide adenylyltransferase activity|upregulation of ATP:polynucleotidylexotransferase activity|up-regulation of polyadenylate nucleotidyltransferase activity|activation of poly(A) synthetase activity|upregulation of AMP polynucleotidylexotransferase activity|positive regulation of poly(A) synthetase activity|upregulation of polynucleotide adenylyltransferase activity|up-regulation of poly-A polymerase activity|up-regulation of NTP polymerase activity|upregulation of terminal riboadenylate transferase activity|positive regulation of poly(A) hydrolase activity|activation of poly-A polymerase activity|up-regulation of RNA formation factors, PF1|up regulation of poly(A) hydrolase activity|up-regulation of polyadenylate polymerase activity|up regulation of RNA adenylating enzyme activity|positive regulation of RNA adenylating enzyme activity|activation of RNA adenylating enzyme activity|positive regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|up regulation of polyadenylic acid polymerase activity|positive regulation of polyadenylic polymerase activity|up-regulation of polyadenylate synthetase activity|up-regulation of poly(A) polymerase activity|up-regulation of ATP:polynucleotidylexotransferase activity|positive regulation of polyadenylic acid polymerase activity|activation of ATP:polynucleotidylexotransferase activity|activation of polyadenylic acid polymerase activity|up regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|upregulation of polyadenylate nucleotidyltransferase activity|up regulation of ATP:polynucleotide adenylyltransferase activity|up-regulation of ATP-polynucleotide adenylyltransferase activity|up-regulation of AMP polynucleotidylexotransferase activity|activation of AMP polynucleotidylexotransferase activity|activation of RNA formation factors, PF1|up regulation of polyadenylic polymerase activity|upregulation of NTP polymerase activity|positive regulation of ATP:polynucleotide adenylyltransferase activity|up-regulation of poly(A) synthetase activity|activation of ATP:polynucleotide adenylyltransferase activity|up regulation of polynucleotide adenylyltransferase activity Any process that activates or increases the frequency, rate or extent of polynucleotide adenylyltransferase activity. GO:1904246 negative regulation of polynucleotide adenylyltransferase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904246 negative regulation of polyadenylic acid polymerase activity|down-regulation of polyadenylic acid polymerase activity|downregulation of polyadenylic polymerase activity|down regulation of NTP polymerase activity|inhibition of poly(A) hydrolase activity|down-regulation of ATP:polynucleotidylexotransferase activity|down-regulation of ATP:polynucleotide adenylyltransferase activity|negative regulation of ATP:polynucleotide adenylyltransferase activity|negative regulation of ATP:polynucleotidylexotransferase activity|down-regulation of AMP polynucleotidylexotransferase activity|downregulation of polyadenylate nucleotidyltransferase activity|negative regulation of AMP polynucleotidylexotransferase activity|down regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|down regulation of polyadenylic polymerase activity|down regulation of polyadenylate polymerase activity|downregulation of NTP polymerase activity|down-regulation of polynucleotide adenylyltransferase activity|inhibition of RNA adenylating enzyme activity|downregulation of poly-A polymerase activity|inhibition of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|negative regulation of terminal riboadenylate transferase activity|down-regulation of terminal riboadenylate transferase activity|inhibition of polyadenylic polymerase activity|down regulation of polyadenylate synthetase activity|inhibition of polyadenylic acid polymerase activity|downregulation of RNA formation factors, PF1|down regulation of poly(A) polymerase activity|downregulation of polyadenylate polymerase activity|down regulation of ATP-polynucleotide adenylyltransferase activity|inhibition of ATP:polynucleotide adenylyltransferase activity|down regulation of poly-A polymerase activity|down regulation of poly(A) synthetase activity|downregulation of ATP:polynucleotidylexotransferase activity|downregulation of poly(A) polymerase activity|downregulation of polyadenylate synthetase activity|inhibition of poly-A polymerase activity|down regulation of RNA formation factors, PF1|downregulation of ATP-polynucleotide adenylyltransferase activity|inhibition of polynucleotide adenylyltransferase activity|negative regulation of polyadenylate nucleotidyltransferase activity|downregulation of AMP polynucleotidylexotransferase activity|down-regulation of polyadenylate nucleotidyltransferase activity|inhibition of terminal riboadenylate transferase activity|downregulation of poly(A) synthetase activity|down-regulation of NTP polymerase activity|negative regulation of NTP polymerase activity|down regulation of ATP:polynucleotidylexotransferase activity|down regulation of AMP polynucleotidylexotransferase activity|negative regulation of polyadenylate polymerase activity|inhibition of ATP:polynucleotidylexotransferase activity|down regulation of RNA adenylating enzyme activity|down-regulation of polyadenylate polymerase activity|negative regulation of poly(A) hydrolase activity|down-regulation of poly(A) hydrolase activity|inhibition of AMP polynucleotidylexotransferase activity|inhibition of RNA formation factors, PF1|down regulation of polyadenylic acid polymerase activity|inhibition of polyadenylate nucleotidyltransferase activity|negative regulation of polyadenylate synthetase activity|negative regulation of poly(A) polymerase activity|down-regulation of polyadenylate synthetase activity|down-regulation of poly(A) polymerase activity|inhibition of NTP polymerase activity|down-regulation of ATP-polynucleotide adenylyltransferase activity|negative regulation of ATP-polynucleotide adenylyltransferase activity|downregulation of RNA adenylating enzyme activity|down regulation of ATP:polynucleotide adenylyltransferase activity|negative regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|down-regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|negative regulation of polyadenylic polymerase activity|down-regulation of polyadenylic polymerase activity|negative regulation of poly(A) synthetase activity|downregulation of polyadenylic acid polymerase activity|down-regulation of poly(A) synthetase activity|down regulation of polynucleotide adenylyltransferase activity|inhibition of polyadenylate polymerase activity|downregulation of ATP:polynucleotide adenylyltransferase activity|down regulation of terminal riboadenylate transferase activity|inhibition of poly(A) polymerase activity|inhibition of polyadenylate synthetase activity|downregulation of poly(A) hydrolase activity|negative regulation of poly-A polymerase activity|down-regulation of poly-A polymerase activity|inhibition of ATP-polynucleotide adenylyltransferase activity|downregulation of polynucleotide adenylyltransferase activity|downregulation of terminal riboadenylate transferase activity|negative regulation of RNA formation factors, PF1|down-regulation of RNA formation factors, PF1|negative regulation of RNA adenylating enzyme activity|down-regulation of RNA adenylating enzyme activity|inhibition of poly(A) synthetase activity|down regulation of polyadenylate nucleotidyltransferase activity|downregulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|down regulation of poly(A) hydrolase activity Any process that stops, prevents or reduces the frequency, rate or extent of polynucleotide adenylyltransferase activity. GO:1904245 regulation of polynucleotide adenylyltransferase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904245 regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|regulation of polyadenylate nucleotidyltransferase activity|regulation of polyadenylic polymerase activity|regulation of NTP polymerase activity|regulation of polyadenylate polymerase activity|regulation of poly-A polymerase activity|regulation of RNA formation factors, PF1|regulation of polyadenylate synthetase activity|regulation of poly(A) polymerase activity|regulation of ATP-polynucleotide adenylyltransferase activity|regulation of poly(A) synthetase activity|regulation of ATP:polynucleotidylexotransferase activity|regulation of AMP polynucleotidylexotransferase activity|regulation of RNA adenylating enzyme activity|regulation of polyadenylic acid polymerase activity|regulation of ATP:polynucleotide adenylyltransferase activity|regulation of terminal riboadenylate transferase activity|regulation of poly(A) hydrolase activity Any process that modulates the frequency, rate or extent of polynucleotide adenylyltransferase activity. GO:1904255 negative regulation of iron ion transmembrane transporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904255 inhibition of iron cation channel activity|downregulation of iron channel activity|downregulation of iron-specific channel activity|down-regulation of iron channel activity|down regulation of iron-specific channel activity|inhibition of iron-specific channel activity|negative regulation of iron cation channel activity|inhibition of iron channel activity|down-regulation of iron cation channel activity|downregulation of iron cation channel activity|negative regulation of iron channel activity|negative regulation of iron-specific channel activity|down regulation of iron cation channel activity|down regulation of iron channel activity|down-regulation of iron-specific channel activity Any process that stops, prevents or reduces the frequency, rate or extent of an iron transmembrane transporter activity. CHEBI:15438 coproporphyrinogen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15438 GO:1904254 regulation of iron ion transmembrane transporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904254 regulation of iron-specific channel activity|regulation of iron channel activity|regulation of iron cation channel activity Any process that modulates the frequency, rate or extent of an iron transmembrane transporter activity. CHEBI:15437 uroporphyrinogen III biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15437 GO:1904253 positive regulation of bile acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904253 up-regulation of bile acid metabolism|activation of bile acid metabolism|up regulation of bile acid metabolic process|activation of bile acid metabolic process|positive regulation of bile acid metabolism|up regulation of bile acid metabolism|up-regulation of bile acid metabolic process|upregulation of bile acid metabolism|upregulation of bile acid metabolic process Any process that activates or increases the frequency, rate or extent of bile acid metabolic process. CHEBI:40407 2-octaprenylphenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_40407 GO:1904252 negative regulation of bile acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904252 down regulation of bile acid metabolic process|downregulation of bile acid metabolic process|negative regulation of bile acid metabolism|down-regulation of bile acid metabolism|down-regulation of bile acid metabolic process|downregulation of bile acid metabolism|down regulation of bile acid metabolism|inhibition of bile acid metabolism|inhibition of bile acid metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of bile acid metabolic process. CHEBI:15439 coproporphyrinogen III biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15439 GO:1904251 regulation of bile acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904251 regulation of bile acid metabolism Any process that modulates the frequency, rate or extent of bile acid metabolic process. GO:0052490 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052490 CHEBI:15434 magnesium 13(1)-hydroxyprotoporphyrin 13-monomethyl ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15434 GO:1904250 positive regulation of age-related resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904250 upregulation of senescence-induced resistance|upregulation of mature seedling resistance|up-regulation of adult seedling resistance|upregulation of age-related resistance|up regulation of ARR|positive regulation of ARR|activation of ARR|upregulation of flowering-induced resistance|up-regulation of mature seedling resistance|up regulation of senescence-induced resistance|upregulation of adult seedling resistance|positive regulation of senescence-induced resistance|up-regulation of age-related resistance|activation of age-related resistance|activation of mature seedling resistance|up-regulation of flowering-induced resistance|activation of senescence-induced resistance|up-regulation of ARR|positive regulation of mature seedling resistance|up regulation of adult seedling resistance|positive regulation of adult seedling resistance|up regulation of mature seedling resistance|activation of flowering-induced resistance|up-regulation of senescence-induced resistance|up regulation of age-related resistance|upregulation of ARR|positive regulation of flowering-induced resistance|activation of adult seedling resistance|up regulation of flowering-induced resistance Any process that activates or increases the extent of age-related resistance. CHEBI:15433 magnesium 13(1)-oxoprotoporphyrin 13-monomethyl ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15433 CHEBI:15435 protoporphyrinogen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15435 GO:0052494 occlusion by host of symbiont vascular system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052494 The process in which an organism reduces the flow of fluid within its symbiont's vascular system, the vessels and tissue that carry or circulate fluids, such as blood, lymph or sap, through the body of an animal or plant. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:15430 protoporphyrin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15430 GO:0052493 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052493 GO:0052492 obsolete negative regulation by host of symbiont signal transduction pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052492 down regulation by host of symbiont signal transduction pathway|inhibition by host of symbiont signal transduction pathway|down-regulation by host of symbiont signal transduction pathway|negative modulation by organism of symbiont signal transduction pathway|downregulation by host of symbiont signal transduction pathway OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the symbiont signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:15432 magnesium protoporphyrin 13-monomethyl ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15432 GO:0052491 obsolete negative regulation by organism of symbiont salicylic acid-mediated defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052491 suppression by organism of symbiont salicylic acid-mediated defense response|suppression of symbiont SA mediated defense response|negative regulation by organism of symbiont salicylic acid-mediated defense response|negative regulation of symbiont SA-mediated defense response OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the salicylic acid-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:15431 magnesium protoporphyrin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15431 GO:0052498 obsolete pathogen-associated molecular pattern dependent induction by organism of symbiont innate immunity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052498 general elicitor-dependent induction of symbiont innate immunity|MAMP dependent induction of symbiont innate immunity|PAMP dependent induction of symbiont innate immunity|pathogen-associated molecular pattern dependent induction by organism of symbiont innate immunity|pathogen-associated molecular pattern dependent activation by organism of symbiont innate immunity|PAMP dependent activation of symbiont innate immunity|MAMP dependent activation of symbiont innate immunity|general elicitor-dependent activation of symbiont innate immunity OBSOLETE. This term was not defined before being made obsolete. GO:0052497 occlusion by organism of xylem in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052497 occlusion by organism of xylem in other organism during symbiotic interaction The process in which an organism reduces the flow of fluid within the xylem, the tissue in plants that carries water and nutrients up from the roots to the shoot and leaves, of a second organism, where the two organisms are in a symbiotic interaction. GO:0052496 occlusion by host of symbiont xylem biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052496 The process in which an organism reduces the flow of fluid within the symbiont xylem, the tissue in plants that carries water and nutrients up from the roots to the shoot and leaves. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052495 occlusion by organism of vascular system in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052495 occlusion by organism of vascular system in other organism during symbiotic interaction The process in which an organism reduces the flow of fluid within its second organism's vascular system, the vessels and tissue that carry or circulate fluids, such as blood, lymph or sap, through the body of an animal or plant, where the two organisms are in a symbiotic interaction. GO:1904259 regulation of basement membrane assembly involved in embryonic body morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904259 Any process that modulates the frequency, rate or extent of basement membrane assembly involved in embryonic body morphogenesis. GO:1904258 nuclear dicing body assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904258 D body formation|D body assembly|nuclear dicing body formation The aggregation, arrangement and bonding together of a set of components to form a nuclear dicing body. GO:1904257 zinc ion import into Golgi apparatus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904257 zinc ion import into Golgi membrane|zinc II ion import across Golgi membrane|zinc ion import across Golgi membrane|zinc(2+) import across Golgi membrane The directed import of zinc(2+) from the cytosol across the Golgi membrane into the Golgi apparatus. GO:1904256 positive regulation of iron ion transmembrane transporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904256 upregulation of iron cation channel activity|positive regulation of iron-specific channel activity|up regulation of iron-specific channel activity|up regulation of iron channel activity|positive regulation of iron transmembrane transporter activity|activation of iron channel activity|up-regulation of iron cation channel activity|activation of iron cation channel activity|upregulation of iron-specific channel activity|up-regulation of iron channel activity|positive regulation of iron cation channel activity|up regulation of iron cation channel activity|up-regulation of iron-specific channel activity|activation of iron-specific channel activity|positive regulation of iron channel activity|upregulation of iron channel activity Any process that activates or increases the frequency, rate or extent of an iron transmembrane transporter activity. GO:1904266 regulation of Schwann cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904266 Any process that modulates the frequency, rate or extent of Schwann cell chemotaxis. UBERON:0007037 mechanosensory system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007037 GO:1904265 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1904265 GO:1904264 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1904264 GO:1904263 positive regulation of TORC1 signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904263 up-regulation of TORC1 signaling|up-regulation of TORC1 signal transduction|upregulation of TORC1 signaling|upregulation of TORC1 signal transduction|up regulation of TORC1 signaling|activation of TORC1 signaling|up regulation of TORC1 signal transduction|activation of TORC1 signal transduction|positive regulation of TORC1 signal transduction Any process that activates or increases the frequency, rate or extent of TORC1 signaling. GO:1904262 negative regulation of TORC1 signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904262 negative regulation of TORC1 signal transduction|down-regulation of TORC1 signal transduction|inhibition of TORC1 signaling|inhibition of TORC1 signal transduction|down regulation of TORC1 signaling|downregulation of TORC1 signaling|down regulation of TORC1 signal transduction|downregulation of TORC1 signal transduction|down-regulation of TORC1 signaling Any process that stops, prevents or reduces the frequency, rate or extent of TORC1 signaling. CHEBI:15467 (3S)-3-hydroxy-3-methylglutaryl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15467 GO:1904261 positive regulation of basement membrane assembly involved in embryonic body morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904261 upregulation of basement membrane assembly involved in embryonic body morphogenesis|up regulation of basement membrane assembly involved in embryonic body morphogenesis|activation of basement membrane assembly involved in embryonic body morphogenesis|up-regulation of basement membrane assembly involved in embryonic body morphogenesis Any process that activates or increases the frequency, rate or extent of basement membrane assembly involved in embryonic body morphogenesis. CHEBI:15466 (S)-methylmalonyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15466 GO:1904260 negative regulation of basement membrane assembly involved in embryonic body morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904260 down regulation of basement membrane assembly involved in embryonic body morphogenesis|downregulation of basement membrane assembly involved in embryonic body morphogenesis|down-regulation of basement membrane assembly involved in embryonic body morphogenesis|inhibition of basement membrane assembly involved in embryonic body morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of basement membrane assembly involved in embryonic body morphogenesis. CHEBI:15469 alk-2-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15469 CHEBI:15468 3'-dephospho-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15468 CHEBI:15463 cinnamoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15463 CHEBI:15465 (R)-methylmalonyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15465 CHEBI:15464 (E,E)-piperonyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15464 CHEBI:15461 cis-tetradec-11-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15461 CHEBI:15460 trans-tetradec-11-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15460 GO:1904269 cell leading edge cell cortex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1904269 peripheral cytoplasm of cell leading edge|cell periphery of cell leading edge|peripheral cytoplasm of front of cell|cell periphery of front of cell|peripheral cytoplasm of leading edge of cell|cell periphery of leading edge of cell|cell cortex of cell leading edge|cell cortex of front of cell|cell cortex of leading edge of cell The cell cortex of the leading edge of a cell. GO:1904268 positive regulation of Schwann cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904268 up regulation of Schwann cell chemotaxis|activation of Schwann cell chemotaxis|up-regulation of Schwann cell chemotaxis|upregulation of Schwann cell chemotaxis Any process that activates or increases the frequency, rate or extent of Schwann cell chemotaxis. GO:1904267 negative regulation of Schwann cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904267 downregulation of Schwann cell chemotaxis|down-regulation of Schwann cell chemotaxis|inhibition of Schwann cell chemotaxis|down regulation of Schwann cell chemotaxis Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell chemotaxis. GO:1904277 negative regulation of wax biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904277 down regulation of wax biosynthesis|down regulation of wax biosynthetic process|down regulation of wax formation|inhibition of wax biosynthetic process|inhibition of wax biosynthesis|downregulation of wax synthesis|downregulation of wax formation|down-regulation of wax anabolism|negative regulation of wax anabolism|down-regulation of wax synthesis|negative regulation of wax synthesis|inhibition of wax anabolism|down-regulation of wax formation|negative regulation of wax formation|inhibition of wax synthesis|down-regulation of wax biosynthetic process|negative regulation of wax biosynthesis|down-regulation of wax biosynthesis|inhibition of wax formation|down regulation of wax anabolism|downregulation of wax biosynthetic process|downregulation of wax biosynthesis|down regulation of wax synthesis|downregulation of wax anabolism Any process that stops, prevents or reduces the frequency, rate or extent of wax biosynthetic process. UBERON:0007026 presumptive gut biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007026 primordial gut|primordial digestive tube|embryonic digestive tube|future digestive tube|primitive gut|future digestive tract|future gut GO:1904276 regulation of wax biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904276 regulation of wax formation|regulation of wax anabolism|regulation of wax biosynthesis|regulation of wax synthesis Any process that modulates the frequency, rate or extent of wax biosynthetic process. CHEBI:15459 (3S)-citryl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15459 GO:1904275 tricellular tight junction disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904275 The disaggregation of a tricellular tight junction into its constituent components. GO:1904274 tricellular tight junction assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904274 tricellular tight junction formation The aggregation, arrangement and bonding together of a set of components to form a tricellular tight junction. UBERON:0007023 adult organism biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007023 adults|adult A multicellular organism that existence_ends_with a post-juvenile adult stage and existence_starts_with a post-juvenile adult stage. GO:1904273 L-alanine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904273 The directed import of L-alanine from the extracellular region across the plasma membrane and into the cytosol. CHEBI:15456 (R)-3-hydroxyacyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15456 UBERON:0007021 sexually immature organism biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007021 juveniles|juvenile organism|juvenile A multicellular organism that is at the juvenile stage. GO:1904272 L-tryptophan import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904272 The directed movement of L-tryptophan from outside of a cell, across the plasma membrane and into the cytosol. CHEBI:15455 (S)-3-hydroxyacyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15455 GO:1904271 L-proline import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904271 L-proline import into cell The directed movement of L-proline from outside of a cell, across the plasma membrane and into the cytosol. CHEBI:15457 citramalyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15457 GO:1904270 pyroptosome complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904270 ASC pyroptosome assembly|ASC pyroptosome formation|pyroptosome complex formation The aggregation, arrangement and bonding together of a set of components to form a pyroptosome complex. CHEBI:15452 (R)-3-hydroxybutanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15452 CHEBI:15451 (2S)-2-methylacyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15451 CHEBI:15454 (3S)-3-carboxy-3-hydroxypropanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15454 CHEBI:15453 (S)-3-hydroxybutanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15453 CHEBI:15450 (2R)-2-methylacyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15450 GO:0003436 regulation of cell adhesion involved in growth plate cartilage morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003436 Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix and contributes to the shaping of the growth plate cartilage of an endochondral bone. GO:0003435 smoothened signaling pathway involved in growth plate cartilage chondrocyte development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003435 hedgehog signaling pathway involved in growth plate cartilage chondrocyte development|hh signaling pathway involved in growth plate cartilage chondrocyte development|smoothened signalling pathway involved in growth plate cartilage chondrocyte development The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened that contributes to the progression of a growth plate cartilage chondrocyte over time. GO:0003437 regulation of cell communication involved in growth plate cartilage morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003437 Any process that modulates the frequency, rate or extent of cell communication that contributes to the shaping of the growth plate cartilage. GO:0003432 cell growth involved in growth plate cartilage chondrocyte morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003432 The growth of a growth plate cartilage chondrocyte, where growth contributes to the shaping of the chondrocyte over time. GO:0003431 growth plate cartilage chondrocyte development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003431 The progression of a growth plate cartilage chondrocyte over time from after its fate commitment to the mature cell. CHEBI:64381 1-acyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64381 CHEBI:88351 linoleoyl-containing glycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88351 GO:0003434 BMP signaling pathway involved in growth plate cartilage chondrocyte development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003434 BMP signalling pathway involved in growth plate cartilage chondrocyte development A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the progression of a growth plate cartilage chondrocyte over time. CHEBI:88350 2-phosphoglycerate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88350 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003433 The progression of a chondrocyte over time from after its commitment to its mature state where the chondrocyte will contribute to the shaping of an endochondral bone. GO:0003430 growth plate cartilage chondrocyte growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003430 growth plate cartilage chondrocyte hypertrophy The growth of a growth plate cartilage chondrocyte, where growth contributes to the progression of the chondrocyte over time from one condition to another. PR:000002112 vascular endothelial growth factor receptor 2 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000002112 protein-tyrosine kinase receptor flk-1|CD309|KDR|kinase insert domain receptor|fetal liver kinase 1|VEGFR-2|FLK-1|FLK1|kinase NYK A vascular endothelial growth factor receptor that is a translation product of the human KDR gene or a 1:1 ortholog thereof. NCBITaxon:3176 Zygnematales organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_3176 CHEBI:64397 asperfuranone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64397 CHEBI:64396 1-oleyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64396 CHEBI:88347 15(S)-HEPE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88347 CHEBI:64398 monodictyphenone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64398 PR:000002122 C-C motif chemokine 2 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000002122 platelet-derived growth factor-inducible protein JE|monocyte secretory protein JE|CCL2|monocyte chemoattractant protein 1|small-inducible cytokine A2|MCAF|HC11|monocyte chemotactic and activating factor|monocyte chemotactic protein 1|Je|SCYA2|MCP-1|MCP1 An eotaxin-like cytokine that is a translation product of the human CCL2 gene or a 1:1 ortholog thereof. PR:000002125 C-C motif chemokine 7 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000002125 small-inducible cytokine A7|monocyte chemoattractant protein 3|intercrine/chemokine MARC|protein FIC|MCP-3|Fic|NC28|monocyte chemotactic protein 3|SCYA7|SCYA6|MCP3|CCL7 An eotaxin-like cytokine that is a translation product of the human CCL7 gene or a 1:1 ortholog thereof. GO:0003414 chondrocyte morphogenesis involved in endochondral bone morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003414 The process in which the structures of a chondrocyte that will contribute to bone development are generated and organized. GO:0003413 chondrocyte differentiation involved in endochondral bone morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003413 The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage. GO:0003416 endochondral bone growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003416 The increase in size or mass of an endochondral bone that contributes to the shaping of the bone. GO:0003415 chondrocyte hypertrophy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003415 The growth of a chondrocyte, where growth contributes to the progression of the chondrocyte over time. GO:0003410 anterior rotation of the optic cup biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003410 A 90 degree-rotation of the optic cup resulting in its alignment with the anterior-posterior body axis. GO:0003412 establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003412 The specification and formation of the apicobasal polarity of an epithelial cell that contributes to the shaping of a camera-type eye. GO:0003411 cell motility involved in camera-type eye morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003411 Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another and contributes to the physical shaping or formation of the camera-type eye. GO:0003418 growth plate cartilage chondrocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003418 The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the growth of a bone. A chondrocyte is a polymorphic cell that forms cartilage. GO:0003417 growth plate cartilage development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003417 The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones as they elongate or grow. GO:0003419 growth plate cartilage chondrocyte proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003419 The multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population. GO:0003425 establishment of mitotic spindle orientation involved in growth plate cartilage chondrocyte division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003425 A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures and contributes to oriented chondrocyte division in the growth plate. GO:0003424 establishment of cell polarity involved in growth plate cartilage chondrocyte division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003424 growth plate cartilage chondrocyte polarization The cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization that results in the directional division of a growth plate cartilage chondrocyte. GO:0003427 regulation of cytoskeleton polarization involved in growth plate cartilage chondrocyte division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003427 regulation of cytoskeleton polarization involved in growth plate cartilage chondrocyte division by planar cell polarity pathway The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell that modulates the rate, frequency, or extent of the polarization of cytoskeletal structures in a growth plate cartilage chondrocyte. This process results in the oriented division of the cell. CHEBI:146500 D-Galp-(1->3)-D-GalpNAc biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_146500 GO:0003426 cytoskeleton polarization involved in growth plate cartilage chondrocyte division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003426 A process that is carried out at the cellular level which results in the polarization of cytoskeletal structures in a growth plate cartilage chondrocyte. This process results in the oriented division of the cell. GO:0003421 growth plate cartilage axis specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003421 growth plate cartilage axis determination The establishment, maintenance and elaboration of the columnar cartilage along the axis of a long bone that contributes to bone growth. CHEBI:88360 N-(1-naphthyl)carboxamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88360 GO:0003420 regulation of growth plate cartilage chondrocyte proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003420 Any process that modulates the rate, frequency, or extent of the multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population. GO:0003423 growth plate cartilage chondrocyte division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003423 The process resulting in the oriented physical partitioning and separation of a chondrocytes in the growth plate. GO:0003422 growth plate cartilage morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003422 The process in which the anatomical structures of growth plate cartilage are generated and organized. CHEBI:88361 N-(naphthyl)carboxamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88361 PR:000002107 tumor necrosis factor ligand superfamily member 11 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000002107 TRANCE|osteoclast differentiation factor|receptor activator of nuclear factor kappa-B ligand|OPGL|RANKL|TNFSF11|TNF-related activation-induced cytokine|osteoprotegerin ligand|ODF|CD254 A tumor necrosis factor ligand superfamily member 10/11 that is a translation product of the human TNFSF11 gene or a 1:1 ortholog thereof. PR:000002106 tumor necrosis factor ligand superfamily member 10 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000002106 protein TRAIL|apo-2 ligand|TNF-related apoptosis-inducing ligand|apo-2L|TRAIL|TNFSF10|APO2L|CD253 A tumor necrosis factor ligand superfamily member 10/11 that is a translation product of the human TNFSF10 gene or a 1:1 ortholog thereof. PR:000002109 tumor necrosis factor receptor superfamily member 10B biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000002109 CD262|TNFRSF10B|TRAIL receptor 2|TRAIL-R2|TNF-related apoptosis-inducing ligand receptor 2|KILLER|DR5|TRAILR2|death receptor 5|TRICK2|MK|ZTNFR9 A tumor necrosis factor receptor superfamily member 10A/B that is a translation product of the human TNFRSF10B gene or a 1:1 ortholog thereof. PR:000002108 tumor necrosis factor receptor superfamily member 10A biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000002108 APO2|CD261|TNFRSF10A|TRAIL receptor 1|TNF-related apoptosis-inducing ligand receptor 1|TRAIL-R1|DR4|TRAILR1|death receptor 4 A tumor necrosis factor receptor superfamily member 10A/B that is a translation product of the human TNFRSF10A gene or a 1:1 ortholog thereof. No mouse gene has been assigned this name. GO:0003429 growth plate cartilage chondrocyte morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003429 The process in which the structures of a chondrocyte in the growth plate cartilage are generated and organized. GO:0003428 chondrocyte intercalation involved in growth plate cartilage morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003428 The orderly movement of a chondrocyte from one site to another that contributes to the shaping of growth plate cartilage in an endochondral bone. GO:0052403 negative regulation by host of symbiont catalytic activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052403 down-regulation by host of symbiont enzyme activity|negative regulation by host of symbiont enzyme activity|inhibition of symbiont enzyme activity|downregulation by host of symbiont enzyme activity|down regulation by host of symbiont enzyme activity|inhibition by host of symbiont enzyme activity Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont enzyme activity. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052402 obsolete induction by organism of symbiont resistance gene-dependent defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052402 induction by organism of defense response in symbiont by specific elicitors|induction by organism of symbiont resistance gene-dependent defense response|activation by organism of symbiont gene-for-gene resistance|induction by organism of pathogen-race/symbiont plant cultivar-specific resistance in symbiont|induction by organism of symbiont gene-for-gene resistance|activation by organism of defense response in symbiont by specific elicitors|activation by organism of symbiont resistance gene-dependent defense response|activation by organism of pathogen-race/symbiont plant cultivar-specific resistance in symbiont OBSOLETE. The activation by an organism of the resistance gene-dependent defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052401 obsolete induction by organism of defense-related symbiont reactive oxygen species production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052401 activation by organism of defense-related symbiont ROI production|activation by organism of defense-related symbiont reactive oxygen intermediate production|induction by organism of defense-related symbiont reactive oxygen species production|activation by organism of defense-related symbiont reactive oxidative species production|induction by organism of defense-related symbiont AOS production|activation by organism of defense-related symbiont oxidative burst|induction by organism of defense-related symbiont metabolic burst|activation by organism of defense-related symbiont ROS production|activation by organism of defense-related symbiont active oxygen species production|induction by organism of defense-related symbiont ROI production|induction by organism of defense-related symbiont respiratory burst|activation by organism of defense-related symbiont metabolic burst|induction by organism of defense-related symbiont reactive oxygen intermediate production|induction by organism of defense-related symbiont active oxygen species production|induction by organism of defense-related symbiont ROS production|activation by organism of defense-related symbiont reactive oxygen species production|activation by organism of defense-related symbiont AOS production|induction by organism of defense-related symbiont oxidative burst|activation by organism of defense-related symbiont respiratory burst OBSOLETE. The activation by an organism of the production of reactive oxygen species as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052400 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052400 CHEBI:88390 1-hydroxybutan-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88390 GO:0052407 metabolism by organism of carbohydrate in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052407 metabolism by organism of carbohydrate in other organism during symbiotic interaction The chemical reactions and pathways performed by an organism involving carbohydrates within a second organism, where the two organisms are in a symbiotic interaction. GO:0052406 metabolism by host of symbiont carbohydrate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052406 The chemical reactions and pathways performed by an organism involving carbohydrates within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052405 negative regulation by host of symbiont molecular function biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052405 down regulation by host of symbiont protein function|negative regulation by host of symbiont protein function|downregulation by host of symbiont protein function|inhibition of symbiont protein function|down-regulation by host of symbiont protein function|inhibition by host of symbiont protein function Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the functional activity of symbiont proteins. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052404 negative regulation by host of symbiont peptidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052404 downregulation by host of symbiont protease activity|down regulation by host of symbiont protease activity|inhibition by host of symbiont protease activity|negative regulation by host of symbiont protease activity|down-regulation by host of symbiont protease activity|inhibition of symbiont protease activity Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont protease activity, the catalysis of the hydrolysis of peptide bonds in a protein. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052409 metabolism by organism of cell wall cellulose in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052409 metabolism by organism of cell wall cellulose in other organism during symbiotic interaction The chemical reactions and pathways performed by an organism involving cellulose in the cell wall of a second organism, where the two organisms are in a symbiotic interaction. GO:0052408 metabolism by host of symbiont cell wall cellulose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052408 The chemical reactions and pathways performed by an organism involving cellulose in the cell wall of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0003403 optic vesicle formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003403 The developmental process pertaining to the initial formation of the optic vesicle from the lateral wall of the forebrain. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup. GO:0052414 metabolism by host of symbiont glucan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052414 The chemical reactions and pathways performed by an organism involving glucans within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0003402 planar cell polarity pathway involved in axis elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003402 The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal to modulate cytoskeletal elements and control cell polarity that contributes to axis elongation. GO:0052413 metabolism by organism of cell wall pectin in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052413 metabolism by organism of cell wall pectin in other organism during symbiotic interaction The chemical reactions and pathways performed by an organism involving pectin in the cell wall of a second organism, where the two organisms are in a symbiotic interaction. GO:0003405 optic vesicle elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003405 The developmental growth that results in the lengthening of the optic vesicle in the posterior direction. GO:0052412 metabolism by host of symbiont cell wall pectin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052412 The chemical reactions and pathways performed by an organism involving pectin in the cell wall of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0003404 optic vesicle morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003404 The developmental process pertaining to the formation and shaping of the optic vesicle. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup. GO:0052411 metabolism by organism of cell wall chitin in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052411 metabolism by organism of cell wall chitin in other organism during symbiotic interaction The chemical reactions and pathways performed by an organism involving chitin in the cell wall of a second organism, where the two organisms are in a symbiotic interaction. GO:0052418 metabolism by organism of protein in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052418 metabolism by organism of protein in other organism during symbiotic interaction The chemical reactions and pathways performed by an organism involving protein macromolecules within a second organism, where the two organisms are in a symbiotic interaction. GO:0052417 metabolism by host of symbiont protein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052417 The chemical reactions and pathways performed by an organism involving protein macromolecules within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. PR:000016798 titin biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000016798 connectin|TTN|rhabdomyosarcoma antigen MU-RMS-40.14 A protein that is a translation product of the human TTN gene or a 1:1 ortholog thereof. GO:0003401 axis elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003401 elongation of an axis The developmental growth that results in the elongation of a line that defines polarity or symmetry in an anatomical structure. GO:0052416 metabolism by host of symbiont macromolecule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052416 The chemical reactions and pathways performed by an organism involving macromolecules within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0003400 regulation of COPII vesicle coating biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003400 Any process that modulates the rate, frequency, or extent of the addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat. GO:0052415 metabolism by organism of glucan in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052415 metabolism by organism of glucan in other organism during symbiotic interaction The chemical reactions and pathways performed by an organism involving glucans within a second organism, where the two organisms are in a symbiotic interaction. GO:0052419 metabolism by host of substance in symbiont biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052419 The chemical reactions and pathways performed by an organism in its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:15397 (S)-camphor biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15397 CHEBI:15396 (R)-camphor biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15396 CHEBI:15399 (+)-carvone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15399 CHEBI:15398 (+)-exo-5-hydroxycamphor biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15398 CHEBI:15393 (+)-borneol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15393 GO:0003407 neural retina development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003407 The progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells. GO:0052410 metabolism by host of symbiont cell wall chitin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052410 The chemical reactions and pathways performed by an organism involving chitin in the cell wall of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0003406 retinal pigment epithelium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003406 RPE development The progression of the retinal pigment epithelium over time, from its initial formation to the mature structure. The retinal pigment epithelium is the melanin-containing layer of cells between the retina and the choroid that absorbs scattered and reflected light and removes waste products produced by the photoreceptor cells. CHEBI:15392 (1R)-bornane-2,5-dione biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15392 GO:0003409 optic cup structural organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003409 optic cup structural organisation The process that contributes to creating the structural organization of the optic cup. This process pertains to the physical shaping of the rudimentary structure. CHEBI:15395 (+)-bornyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15395 CHEBI:15394 (-)-borneol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15394 GO:0003408 optic cup formation involved in camera-type eye development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003408 The developmental process pertaining to the initial formation of the optic cup, a two-walled vesicle formed from the optic vesicle. GO:0052425 obsolete modification by organism of symbiont morphology or physiology via protein secreted by type II secretion system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052425 modification by organism of symbiont morphology or physiology via protein secreted by type II secretion system OBSOLETE. The process by which an organism effects a change in the structure or function of its symbiont organism, mediated by a substance secreted by a type II secretion system in the organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052424 obsolete modification by organism of symbiont morphology or physiology via protein secreted by type III secretion system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052424 modification by organism of symbiont morphology or physiology via protein secreted by type III secretion system OBSOLETE. The process by which an organism effects a change in the structure or function of its symbiont organism, mediated by a substance secreted by a type III secretion system in the organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052423 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052423 GO:0052422 modulation by host of symbiont catalytic activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052422 modulation by host of symbiont enzyme activity The process in which a host organism effects a change in the enzyme activity of its symbiont organism. GO:0052429 obsolete modulation by organism of symbiont B-cell mediated immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052429 modulation by organism of symbiont B-cell mediated immune response|regulation by organism of symbiont B-cell mediated immune response OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the B-cell mediated immune response of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052428 modulation by host of symbiont molecular function biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052428 modification by host of symbiont molecular function|modification by host of symbiont protein function The process in which an organism effects a change in the function of proteins in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052427 modulation by host of symbiont peptidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052427 modulation by host of symbiont protease activity The process in which an organism effects a change in symbiont peptidase activity, the catalysis of the hydrolysis of peptide bonds in a protein. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052426 obsolete modification by organism of symbiont morphology or physiology via substance secreted by type IV secretion system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052426 modification by organism of symbiont morphology or physiology via substance secreted by type IV secretion system OBSOLETE. The process by which an organism effects a change in the structure or function of its symbiont organism, mediated by a substance secreted by a type IV secretion system in the organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:40356 N-acetyl-alpha-D-galactosamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_40356 CHEBI:39352 dinitrophenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39352 GO:0052421 metabolism by organism of xylan in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052421 metabolism by organism of xylan in other organism during symbiotic interaction The chemical reactions and pathways performed by an organism involving xylan within a second organism, where the two organisms are in a symbiotic interaction. NCBITaxon:3193 Embryophyta organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_3193 land plants|higher plants|land plants|plants GO:0052420 metabolism by host of symbiont xylan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052420 The chemical reactions and pathways performed by an organism involving xylan within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052436 obsolete modulation by organism of defense-related symbiont calcium-dependent protein kinase pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052436 modulation by organism of defense-related symbiont calcium-dependent protein kinase pathway|modulation by organism of defense-related symbiont CDPK pathway OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the symbiont calcium-dependent protein kinase signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052435 obsolete modulation by host of defense-related symbiont MAP kinase-mediated signal transduction pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052435 modulation of defense-related symbiont MAPK-mediated signal transduction pathway by organism|modulation of defense-related symbiont mitogen activated protein kinase-mediated signal transduction pathway by organism OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of symbiont MAP kinase-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052434 obsolete modulation by organism of symbiont cell-mediated immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052434 modulation by organism of symbiont cell-based immune response|modulation by organism of symbiont cell-mediated immune response OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of any form of cell-based immune response of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052433 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052433 GO:0052439 obsolete modulation by organism of defense-related symbiont cell wall callose deposition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052439 modulation by organism of defense-related symbiont cell wall callose deposition OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the deposition of callose by the symbiont in its cell walls, occurring as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052438 obsolete modulation by organism of defense-related symbiont callose deposition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052438 modulation by organism of defense-related symbiont callose deposition OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of callose deposition by the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052437 obsolete modulation by organism of defense-related symbiont calcium ion flux biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052437 modulation by organism of defense-related symbiont calcium ion flux|modulation by organism of defense-related symbiont Ca2+ flux OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of calcium ion fluxes as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:39362 mononitrophenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39362 GO:0052432 obsolete modulation by organism of symbiont apoptosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052432 modulation by organism of symbiont apoptosis|modulation by organism of symbiont apoptotic programmed cell death OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of programmed cell death in the symbiont, where programmed cell death proceeds by apoptosis. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052431 obsolete modulation by organism of symbiont T-cell mediated immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052431 modulation by organism of symbiont T-cell mediated immune response OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the T-cell mediated immune response of a symbiont organism, where the two organisms are in a symbiotic interaction. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052430 modulation by host of symbiont RNA levels biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052430 The alteration by an organism of the levels of RNA in a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:78947 archaeal metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78947 CHEBI:78948 L-2-amino-3-oxobutanoic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78948 CHEBI:64302 cyanamide(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64302 CHEBI:64307 2,4-diaminobutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64307 CHEBI:78940 N-palmitoyl-1,2-dioleoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78940 CHEBI:64315 4-demethylwyosine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64315 CHEBI:78954 (omega-1)-hydroxy fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78954 CHEBI:64328 lysidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64328 CHEBI:78978 (11R)-11-hydroxylauric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78978 CHEBI:64335 N(1)-aminopropylagmatine(3+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64335 CHEBI:64339 N(1)-aminoaminopropylagmatine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64339 CHEBI:78988 O-[S-(3R)-hydroxynonanoylpantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78988 PR:000016724 thyrotropin subunit beta biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000016724 thyrotropin alfa|TSH-B|TSHB|TSH-beta|thyrotropin beta chain|thyroid-stimulating hormone subunit beta A glycoprotein hormone beta chain that is a translation product of the human TSHB gene or a 1:1 ortholog thereof. CHEBI:64345 MALDI matrix material biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64345 CHEBI:64344 2',4',6'-trihydroxyacetophenone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64344 CHEBI:78983 O-[S-(3R)-hydroxypentanoylpantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78983 CHEBI:78981 UDP-2-acetamido-2-deoxy-3-dehydro-alpha-D-glucopyranose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78981 CHEBI:78987 O-[S-(3R)-hydroxyheptanoylpantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78987 CHEBI:78986 O-[S-(3R)-hydroxy-5-methylhexanoylpantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78986 CHEBI:78985 O-[S-(3R)-hydroxy-4-methylhexanoylpantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78985 CHEBI:64353 UDP-N-acetyl-alpha-D-glucosamine 3-phosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64353 CHEBI:64351 beta-D-Manp-(1->4)-D-Glcp biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64351 CHEBI:88306 4-nitrophenols biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88306 CHEBI:8927 S-(2,4-dinitrophenyl)glutathione biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_8927 CHEBI:78994 1,2-dipalmitoyl-sn-glycero-3-phospho-(1'-D-myo-inositol-3',5'-bisphosphate)(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78994 CHEBI:78993 1,2-dipalmitoylglycero-3-phospho-(1'-D-myo-inositol-3'-phosphate)(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78993 CHEBI:78995 1,2-dipalmitoyl-sn-glycero-3-phospho-(1'D-myo-inositol-3'-phosphate)(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78995 CHEBI:64362 UDP-N-acetyl-alpha-D-glucosamine 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64362 CHEBI:88332 aralkylammonium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88332 CHEBI:64361 beta-sesquiphellandrene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64361 CHEBI:64368 3-hydroxyproline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64368 CHEBI:64365 aralkylamino compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64365 CHEBI:64373 emericellamide A biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64373 CHEBI:64372 emericellamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64372 CHEBI:64379 1-acyl-sn-glycero-3-phosphoserine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64379 CHEBI:30924 L-tartrate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30924 CHEBI:30923 4-hydroxy-2-oxoglutaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30923 CHEBI:30921 glutarate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30921 CHEBI:30920 3-hydroxy-3-methylglutarate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30920 CHEBI:29934 (1s,4s)-prephenate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29934 CHEBI:30929 2,3-dihydroxybutanedioate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30929 GO:1904159 megasporocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904159 megaspore mother cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a megasporocyte. CHEBI:30928 meso-tartrate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30928 GO:1904158 axonemal central apparatus assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904158 axonemal central apparatus formation The aggregation, arrangement and bonding together of a set of components to form an axonemal central apparatus. CHEBI:30927 D-tartrate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30927 GO:1904157 DN4 thymocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904157 The process in which a relatively unspecialized cell acquires the specialized features of a DN4 thymocyte. A DN4 thymocyte is a CD4-,CD8- thymocyte that is also CD44-,CD25-. CHEBI:30926 3-oxalomalic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30926 GO:1904167 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1904167 BSPO:0015014 immediately_superficial_to biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BSPO_0015014 BSPO:0015014 GO:1904166 obsolete negative regulation of cholesterol homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904166 down regulation of cholesterol homeostasis|downregulation of cholesterol homeostasis|down-regulation of cholesterol homeostasis|inhibition of cholesterol homeostasis OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of cholesterol homeostasis. GO:1904165 obsolete positive regulation of triglyceride homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904165 up regulation of triglyceride homeostasis|up-regulation of triacylglycerol homeostasis|upregulation of triglyceride homeostasis|upregulation of triacylglycerol homeostasis|activation of triglyceride homeostasis|up-regulation of triglyceride homeostasis|up regulation of triacylglycerol homeostasis|activation of triacylglycerol homeostasis|positive regulation of triacylglycerol homeostasis OBSOLETE. Any process that activates or increases the frequency, rate or extent of triglyceride homeostasis. GO:1904164 obsolete negative regulation of triglyceride homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904164 down-regulation of triacylglycerol homeostasis|negative regulation of triacylglycerol homeostasis|downregulation of triglyceride homeostasis|down regulation of triglyceride homeostasis|inhibition of triacylglycerol homeostasis|inhibition of triglyceride homeostasis|down regulation of triacylglycerol homeostasis|downregulation of triacylglycerol homeostasis|down-regulation of triglyceride homeostasis OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of triglyceride homeostasis. GO:1904163 obsolete regulation of triglyceride homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904163 regulation of triacylglycerol homeostasis OBSOLETE. Any process that modulates the frequency, rate or extent of triglyceride homeostasis. GO:1904162 obsolete 5'-3' exodeoxyribonuclease activity involved in UV-damage excision repair biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1904162 5'-3' exodeoxyribonuclease activity involved in UVER|5'-3' exodeoxyribonuclease activity involved in AER|5'-3' exodeoxyribonuclease activity involved in alternative excision repair|5'-3' exodeoxyribonuclease activity involved in UVDE-dependent excision repair|5'-3' exodeoxyribonuclease activity involved in UV-damaged DNA endonuclease-dependent excision repair OBSOLETE. Any 5'-3' exodeoxyribonuclease activity that is involved in UV-damage excision repair. GO:1904161 DNA synthesis involved in UV-damage excision repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904161 mitotic DNA repair synthesis involved in UVDE-dependent excision repair|DNA synthesis involved in UVER|mitotic DNA repair synthesis involved in UVER|mitotic DNA repair synthesis involved in UV-damaged DNA endonuclease-dependent excision repair|DNA synthesis during UVDE-dependent excision repair|DNA synthesis during UV-damaged DNA endonuclease-dependent excision repair|DNA synthesis involved in AER|DNA synthesis during UVER|DNA synthesis involved in alternative excision repair|mitotic DNA repair synthesis involved in UV-damage excision repair|DNA synthesis involved in UV-damaged DNA endonuclease-dependent excision repair|DNA synthesis during UV-damage excision repair|DNA synthesis involved in UVDE-dependent excision repair Any DNA synthesis that is involved in UV-damage excision repair. GO:1904160 protein localization to chloroplast starch grain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904160 protein localisation in chloroplast starch grain|protein localization in chloroplast starch grain|protein localisation to chloroplast starch grain A process in which a protein is transported to, or maintained in, a location within a chloroplast starch grain. CHEBI:30936 L-citramalate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30936 CHEBI:29947 glycine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29947 CHEBI:30935 3-phosphonopyruvic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30935 CHEBI:30934 D-citramalate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30934 CHEBI:30933 3-phosphonooxypyruvic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30933 CHEBI:30939 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30939 CHEBI:30938 6-aminopenicillanate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30938 GO:1904169 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1904169 GO:1904168 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1904168 GO:1904178 negative regulation of adipose tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904178 down regulation of adipose tissue development|inhibition of adipose tissue development|downregulation of adipogenesis|down regulation of adipogenesis|inhibition of adipogenesis|down-regulation of adipose tissue development|downregulation of adipose tissue development|down-regulation of adipogenesis|negative regulation of adipogenesis Any process that stops, prevents or reduces the frequency, rate or extent of adipose tissue development. GO:1904177 regulation of adipose tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904177 regulation of adipogenesis Any process that modulates the frequency, rate or extent of adipose tissue development. GO:1904176 carbon phosphorus lyase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1904176 IntAct:EBI-6471348 A protein complex which is capable of carbon phosphorus lyase activity. GO:1904175 positive regulation of histone demethylase activity (H3-K4 specific) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904175 upregulation of histone demethylase activity (H3-K4 specific)|up regulation of histone demethylase activity (H3-K4 specific)|activation of histone demethylase activity (H3-K4 specific)|up-regulation of histone demethylase activity (H3-K4 specific) Any process that activates or increases the frequency, rate or extent of histone demethylase activity (H3-K4 specific). GO:1904174 negative regulation of histone demethylase activity (H3-K4 specific) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904174 down regulation of histone demethylase activity (H3-K4 specific)|downregulation of histone demethylase activity (H3-K4 specific)|down-regulation of histone demethylase activity (H3-K4 specific)|inhibition of histone demethylase activity (H3-K4 specific) Any process that stops, prevents or reduces the frequency, rate or extent of histone demethylase activity (H3-K4 specific). GO:1904173 regulation of histone demethylase activity (H3-K4 specific) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904173 Any process that modulates the frequency, rate or extent of histone demethylase activity (H3-K4 specific). GO:1904172 positive regulation of bleb assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904172 upregulation of cell blebbing|upregulation of bleb assembly|up regulation of cell blebbing|activation of cell blebbing|positive regulation of cell blebbing|up regulation of bleb assembly|activation of bleb assembly|up-regulation of cell blebbing|up-regulation of bleb assembly Any process that activates or increases the frequency, rate or extent of bleb assembly. GO:1904171 negative regulation of bleb assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904171 down regulation of cell blebbing|downregulation of cell blebbing|down regulation of bleb assembly|downregulation of bleb assembly|down-regulation of cell blebbing|negative regulation of cell blebbing|down-regulation of bleb assembly|inhibition of cell blebbing|inhibition of bleb assembly Any process that stops, prevents or reduces the frequency, rate or extent of bleb assembly. GO:1904170 regulation of bleb assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904170 regulation of cell blebbing Any process that modulates the frequency, rate or extent of bleb assembly. CHEBI:30903 (-)-homoisocitric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30903 CHEBI:30909 1-alkyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30909 CHEBI:30907 4-fumarylacetoacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30907 CHEBI:30904 homoisocitrate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30904 GO:1904179 positive regulation of adipose tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904179 positive regulation of adipogenesis|upregulation of adipose tissue development|up regulation of adipogenesis|activation of adipose tissue development|up-regulation of adipose tissue development|upregulation of adipogenesis|up-regulation of adipogenesis|up regulation of adipose tissue development|activation of adipogenesis Any process that activates or increases the frequency, rate or extent of adipose tissue development. GO:1904189 positive regulation of transformation of host cell by virus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904189 up regulation of transformation of host cell by virus|activation of viral transformation|upregulation of viral transformation of host cell|up-regulation of viral transformation|upregulation of transformation of host cell by virus|up regulation of viral transformation of host cell|activation of viral transformation of host cell|positive regulation of viral transformation|positive regulation of viral transformation of host cell|up regulation of viral transformation|activation of transformation of host cell by virus|up-regulation of transformation of host cell by virus|upregulation of viral transformation|up-regulation of viral transformation of host cell Any process that activates or increases the frequency, rate or extent of transformation of host cell by virus. GO:1904188 negative regulation of transformation of host cell by virus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904188 down regulation of viral transformation of host cell|downregulation of transformation of host cell by virus|downregulation of viral transformation of host cell|down-regulation of viral transformation|negative regulation of viral transformation|down regulation of transformation of host cell by virus|inhibition of transformation of host cell by virus|downregulation of viral transformation|down-regulation of viral transformation of host cell|negative regulation of viral transformation of host cell|down regulation of viral transformation|inhibition of viral transformation|inhibition of viral transformation of host cell|down-regulation of transformation of host cell by virus Any process that stops, prevents or reduces the frequency, rate or extent of transformation of host cell by virus. GO:1904187 regulation of transformation of host cell by virus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904187 regulation of viral transformation of host cell|regulation of viral transformation Any process that modulates the frequency, rate or extent of transformation of host cell by virus. GO:1904186 post-anaphase microtubule array organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904186 post-anaphase array organization|PAA organization|post-anaphase microtubule array organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly ofa post-anaphase microtubule array. UBERON:0007198 hermaphrodite anatomical structure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007198 hermaphrodite-specific An anatomical structure present only in hermaphrodites. GO:1904185 equatorial microtubule organizing center assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904185 EMTOC assembly|EMTOC formation|equatorial microtubule organising centre assembly|equatorial microtubule organizing center formation|equatorial microtubule organising centre formation The aggregation, arrangement and bonding together of a set of components to form an equatorial microtubule organizing center. GO:1904184 positive regulation of pyruvate dehydrogenase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904184 upregulation of pyruvate dehydrogenase activity|upregulation of pyruvic dehydrogenase activity|up-regulation of pyruvic acid dehydrogenase activity|up-regulation of pyruvic dehydrogenase activity|activation of pyruvic dehydrogenase activity|up regulation of pyruvate dehydrogenase activity|activation of pyruvate dehydrogenase activity|upregulation of pyruvic acid dehydrogenase activity|positive regulation of pyruvic dehydrogenase activity|up regulation of pyruvic dehydrogenase activity|up-regulation of pyruvate dehydrogenase activity|up regulation of pyruvic acid dehydrogenase activity|activation of pyruvic acid dehydrogenase activity|positive regulation of pyruvic acid dehydrogenase activity Any process that activates or increases the frequency, rate or extent of pyruvate dehydrogenase activity. UBERON:0007197 hermaphroditic organism biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007197 hermaphrodite|dioecious organism multicellular organism that can produce both male and female gametes. GO:1904183 negative regulation of pyruvate dehydrogenase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904183 negative regulation of pyruvic acid dehydrogenase activity|down-regulation of pyruvic acid dehydrogenase activity|down regulation of pyruvate dehydrogenase activity|downregulation of pyruvate dehydrogenase activity|inhibition of pyruvic acid dehydrogenase activity|down-regulation of pyruvic dehydrogenase activity|down-regulation of pyruvate dehydrogenase activity|negative regulation of pyruvic dehydrogenase activity|down regulation of pyruvic acid dehydrogenase activity|inhibition of pyruvate dehydrogenase activity|downregulation of pyruvic acid dehydrogenase activity|downregulation of pyruvic dehydrogenase activity|down regulation of pyruvic dehydrogenase activity|inhibition of pyruvic dehydrogenase activity Any process that stops, prevents or reduces the frequency, rate or extent of pyruvate dehydrogenase activity. UBERON:0007196 tracheobronchial tree biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007196 tracheobronchial system|arbor tracheobronchialis The structure from the trachea, bronchi, and bronchioles that forms the airways that supply air to the lungs. The lining of the tracheobronchial tree consists of ciliated columnar epithelial cells. UBERON:0007195 stroma of bone marrow biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007195 bone marrow stroma The stroma of the bone marrow is all tissue not directly involved in the primary function of hematopoiesis. The yellow bone marrow belongs here, and makes the majority of the bone marrow stroma, in addition to stromal cells located in the red bone marrow. Yellow bone marrow is found in the Medullary cavity. Still, the stroma is indirectly involved in hematopoiesis, since it provides the hematopoietic microenvironment that facilitates hematopoiesis by the parenchymal cells. For instance, they generate colony stimulating factors, affecting hematopoiesis. GO:1904182 regulation of pyruvate dehydrogenase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904182 regulation of pyruvic acid dehydrogenase activity|regulation of pyruvic dehydrogenase activity Any process that modulates the frequency, rate or extent of pyruvate dehydrogenase activity. GO:1904181 positive regulation of membrane depolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904181 up regulation of membrane depolarization|activation of membrane depolarization|up-regulation of membrane depolarization|upregulation of membrane depolarization Any process that activates or increases the frequency, rate or extent of membrane depolarization. GO:1904180 negative regulation of membrane depolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904180 down regulation of membrane depolarization|downregulation of membrane depolarization|down-regulation of membrane depolarization|inhibition of membrane depolarization Any process that stops, prevents or reduces the frequency, rate or extent of membrane depolarization. CHEBI:29918 sulfanylium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29918 CHEBI:29917 thiol group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29917 CHEBI:29919 hydrosulfide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29919 CHEBI:30913 L-pipecolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30913 CHEBI:29924 hydrogenselenite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29924 CHEBI:30912 1-piperideine-2-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30912 CHEBI:30911 glucitol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30911 CHEBI:29920 phosphoramidate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29920 CHEBI:29922 sulfo group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29922 UBERON:0007182 muscle layer of infundibulum of uterine tube biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007182 muscularis of infundibulum of uterine tube|muscle layer of infundibulum of oviduct|muscle layer of infundibulum of fallopian tube A muscle layer that is part of a uterine tube infundibulum. UBERON:0007181 serosa of infundibulum of uterine tube biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007181 serosa of infundibulum of fallopian tube|serosa of infundibulum of oviduct A serous membrane that is part of a uterine tube infundibulum. CHEBI:30918 3-dehydroshikimic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30918 CHEBI:30916 2-oxoglutarate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30916 CHEBI:30915 2-oxoglutaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30915 GO:1904199 positive regulation of regulation of vascular associated smooth muscle cell membrane depolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904199 positive regulation of regulation of vascular smooth muscle cell membrane depolarization|upregulation of regulation of vascular smooth muscle cell membrane depolarization|up regulation of regulation of vascular smooth muscle cell membrane depolarization|activation of regulation of vascular smooth muscle cell membrane depolarization|up-regulation of regulation of vascular smooth muscle cell membrane depolarization Any process that activates or increases the frequency, rate or extent of regulation of vascular smooth muscle cell membrane depolarization. GO:1904198 negative regulation of regulation of vascular associated smooth muscle cell membrane depolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904198 negative regulation of regulation of vascular smooth muscle cell membrane depolarization|down regulation of regulation of vascular smooth muscle cell membrane depolarization|downregulation of regulation of vascular smooth muscle cell membrane depolarization|down-regulation of regulation of vascular smooth muscle cell membrane depolarization|inhibition of regulation of vascular smooth muscle cell membrane depolarization Any process that stops, prevents or reduces the frequency, rate or extent of regulation of vascular smooth muscle cell membrane depolarization. UBERON:0007188 mesothelium of serous pericardium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007188 pericardial mesothelium|mesothelium of pericardium|serous pericardium mesothelium A mesothelium that is part of a serous pericardium. GO:1904197 positive regulation of granulosa cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904197 upregulation of granulosa cell proliferation|up-regulation of granulosa cell proliferation|activation of granulosa cell proliferation|up regulation of granulosa cell proliferation Any process that activates or increases the frequency, rate or extent of granulosa cell proliferation. GO:1904196 negative regulation of granulosa cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904196 downregulation of granulosa cell proliferation|down regulation of granulosa cell proliferation|inhibition of granulosa cell proliferation|down-regulation of granulosa cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of granulosa cell proliferation. CHEBI:8707 quetiapine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_8707 GO:1904195 regulation of granulosa cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904195 Any process that modulates the frequency, rate or extent of granulosa cell proliferation. GO:1904194 positive regulation of cholangiocyte apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904194 upregulation of epithelial cell of bile duct apoptotic process|up-regulation of cholangiocyte apoptotic process|upregulation of cholangiocyte apoptosis|up-regulation of epithelial cell of bile duct apoptosis|up-regulation of epithelial cell of bile duct apoptotic process|upregulation of cholangiocyte apoptotic process|activation of epithelial cell of bile duct apoptosis|activation of epithelial cell of bile duct apoptotic process|up regulation of cholangiocyte apoptosis|positive regulation of epithelial cell of bile duct apoptosis|positive regulation of cholangiocyte apoptosis|up regulation of epithelial cell of bile duct apoptosis|up regulation of cholangiocyte apoptotic process|activation of cholangiocyte apoptotic process|positive regulation of epithelial cell of bile duct apoptotic process|activation of cholangiocyte apoptosis|up regulation of epithelial cell of bile duct apoptotic process|upregulation of epithelial cell of bile duct apoptosis|up-regulation of cholangiocyte apoptosis Any process that activates or increases the frequency, rate or extent of cholangiocyte apoptotic process. GO:1904193 negative regulation of cholangiocyte apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904193 inhibition of epithelial cell of bile duct apoptotic process|inhibition of epithelial cell of bile duct apoptosis|inhibition of cholangiocyte apoptosis|inhibition of cholangiocyte apoptotic process|down regulation of cholangiocyte apoptosis|downregulation of cholangiocyte apoptosis|down-regulation of epithelial cell of bile duct apoptosis|negative regulation of epithelial cell of bile duct apoptosis|down regulation of cholangiocyte apoptotic process|downregulation of cholangiocyte apoptotic process|negative regulation of epithelial cell of bile duct apoptotic process|down-regulation of epithelial cell of bile duct apoptotic process|negative regulation of cholangiocyte apoptosis|down-regulation of cholangiocyte apoptosis|downregulation of epithelial cell of bile duct apoptosis|down regulation of epithelial cell of bile duct apoptosis|downregulation of epithelial cell of bile duct apoptotic process|down-regulation of cholangiocyte apoptotic process|down regulation of epithelial cell of bile duct apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte apoptotic process. GO:1904192 regulation of cholangiocyte apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904192 regulation of cholangiocyte apoptosis|regulation of epithelial cell of bile duct apoptosis|regulation of epithelial cell of bile duct apoptotic process Any process that modulates the frequency, rate or extent of cholangiocyte apoptotic process. GO:1904191 positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in meiotic nuclear division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904191 positive regulation of cyclin-dependent protein kinase activity involved in meiosis|up-regulation of cyclin-dependent protein kinase activity involved in meiotic nuclear division|upregulation of cyclin-dependent protein kinase activity involved in meiotic nuclear division|up regulation of cyclin-dependent protein kinase activity involved in meiotic nuclear division|activation of cyclin-dependent protein kinase activity involved in meiotic nuclear division|positive regulation of CDK activity involved in meiotic nuclear division|stimulation of cyclin-dependent protein kinase activity involved in meiotic nuclear division Any positive regulation of cyclin-dependent protein serine/threonine kinase activity that is involved in meiotic nuclear division. GO:1904190 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1904190 CHEBI:78903 mannoprotein biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78903 CHEBI:78902 L-canavanine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78902 CHEBI:78907 1,2-dioleoyl-sn-glycero-3-phospho-(1'-sn-glycerol-3'-phosphate)(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78907 CHEBI:78904 4,4-dimethyl-8,14-cholestadien-3beta-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78904 CHEBI:78909 12-HPEPE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78909 CHEBI:78908 10(R)-HPO(6,8,12)TrE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78908 CHEBI:78911 1,2-dioctanoyl-sn-glycero-3-phospho-(1'D-myo-inositol-5'-phosphate)(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78911 CHEBI:78918 dotriacontatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78918 CHEBI:78917 triacontahexaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78917 CHEBI:78915 triacontatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78915 CHEBI:78919 dotriacontahexaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78919 CHEBI:78929 N-hexadecanoylphosphatidylethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78929 CHEBI:78920 dotriacontapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78920 CHEBI:78936 hexatriacontapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78936 CHEBI:78935 hexatriacontatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78935 CHEBI:78934 1,2-dioctanoyl-sn-glycero-3-phospho-(1'-D-myo-inositol-3'-phosphate)(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78934 CHEBI:78933 tetratriacontahexaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78933 CHEBI:78939 octatriacontapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78939 CHEBI:78938 octatriacontatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78938 CHEBI:78937 hexatriacontahexaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78937 CHEBI:78932 tetratriacontapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78932 CHEBI:78931 1-acyl-2-hexanoyl-sn-glycero-3-phospho-(1'-D-myo-inositol)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78931 CHEBI:78930 1-acyl-2-hexanoyl-sn-glycero-3-phospho-(1'-D-myo-inositol-5'-phosphate)(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78930 GO:0052568 obsolete response to symbiont phytoalexin production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052568 response to symbiont phytoalexin production OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of phytoalexins produced as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052567 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052567 GO:0052566 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052566 GO:0052565 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052565 GO:0052569 obsolete response to defense-related symbiont nitric oxide production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052569 response to defense-related symbiont nitric oxide production OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of nitric oxide produced as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. UBERON:0007135 neural keel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007135 presumptive central nervous system An intermediate stage (between the neural plate and neural rod) during the early segmentation period in the morphogenesis of the central nervous system primordium; the keel is roughly triangular shaped in cross section. UBERON:0007134 trunk ganglion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007134 trunk ganglia|body ganglion Ganglion which is located in the trunk. UBERON:0007132 head kidney biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007132 anterior kidney|kidney marrow Teleost head kidney consists of fused bilateral lobes located in the anterior part of the kidney. It is analogous to the mammalian bone marrow and the primary site of definitive hematopoiesis[ZFA,modified]. CHEBI:15368 acrolein biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15368 CHEBI:15367 all-trans-retinoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15367 PR:000026291 unmodified amino-acid residue biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000026291 unmodified protein residue|unmodified amino acid chain residue An amino-acid residue that has not been covalently modified by chemical alteration to the side chain or backbone atoms. CHEBI:15369 actinomycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15369 GO:0052560 obsolete induction by organism of symbiont immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052560 induction by organism of symbiont immune response OBSOLETE. Any process by which an organism activates the immune response of the symbiont organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:15364 propynoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15364 CHEBI:15363 N-acetylindoxyl biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15363 CHEBI:15366 acetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15366 CHEBI:15365 acetylsalicylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15365 CHEBI:15360 acetylpyruvate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15360 GO:0052564 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052564 GO:0052563 obsolete negative regulation by organism of symbiont immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052563 negative regulation by organism of symbiont immune response OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the immune response of the symbiont organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:8798 4a,5-dihydroriboflavin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_8798 GO:0052562 suppression by symbiont of host immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052562 down-regulation by symbiont of host immune response|negative regulation by symbiont of host immune response|downregulation by symbiont of host immune response|down regulation by symbiont of host immune response|inhibition by symbiont of host immune response|negative regulation by organism of immune response of other organism involved in symbiotic interaction Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the immune response of the host organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:15362 hydroxyacetone phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15362 CHEBI:15361 pyruvate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15361 GO:0052561 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052561 GO:0052579 (+)-pulegone reductase, (+)-isomenthone as substrate, activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052579 MetaCyc:RXN-5164|EC:1.3.1.81 (+)-isomenthone:NADP+ oxidoreductase activity Catalysis of the reaction: (+)-isomenthone + NADP+ = (+)-pulegone + NADPH + H+. GO:0052578 alpha-farnesene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052578 MetaCyc:RXN-8574|RHEA:27421 (E,E)-alpha-farnesene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (E,E)-alpha-farnesene + diphosphate. GO:0052577 germacrene-D synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052577 MetaCyc:RXN-8562|KEGG_REACTION:R07648|EC:4.2.3.22|RHEA:12016 2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase [(-)-Germacrene D-forming] activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (-)-germacrene D + diphosphate. GO:0052576 carbohydrate storage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052576 The accumulation and maintenance in cells or tissues of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. UBERON:0007125 pharyngeal pouch 4 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007125 4th arch branchial pouch|4th pharyngeal pouch endoderm|4th arch branchial pouch endoderm|4th branchial pouch|visceral pouch 4|fourth branchial pouch|fourth arch pharyngeal pouch|pharyngeal pouches 4|fourth pharyngeal pouch|fourth visceral pouch A pharyngeal pouch between pharyngeal arch 4 and arch 5 or 6 (a fifth arch never establishes in amniotes). UBERON:0007124 pharyngeal pouch 3 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007124 third pharyngeal pouch|3rd pharyngeal pouch endoderm|third arch pharyngeal pouch|3rd branchial pouch|3rd arch branchial pouch endoderm|third visceral pouch|visceral pouch 3|pharyngeal pouches 3|3rd arch branchial pouch A pharyngeal pouch that between pharyngeal arches 3 and 4. UBERON:0007123 pharyngeal pouch 2 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007123 2nd pharyngeal pouch endoderm|2nd branchial pouch|2nd arch branchial pouch endoderm|second pharyngeal pouch|visceral pouch 2|2nd arch pouch endoderm|pharyngeal pouches 2|second visceral pouch|second arch pharyngeal pouch|2nd arch branchial pouch A pharyngeal puch that is between the pharyngeal arches 2 and 3. UBERON:0007122 pharyngeal pouch 1 biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007122 1st arch branchial pouch|1st arch pouch endoderm|first pharyngeal pouch|visceral pouch 1|first visceral pouch|hyomandibular pouch|pharyngeal pouches 1|1st pharyngeal pouch endoderm|1st arch branchial pouch endoderm|1st branchial pouch|first arch pharyngeal pouch A pharyngeal pouch that is between pharyngeal arches 1 and 2. CHEBI:15357 acetylenedicarboxylate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15357 CHEBI:15356 cysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15356 CHEBI:15358 histone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15358 GO:0052571 obsolete response to symbiont immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052571 response to symbiont immune response OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the immune response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:15353 blasticidin S biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15353 GO:0052570 obsolete response to defense-related symbiont reactive oxygen species production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052570 response to defense-related symbiont reactive oxygen species production OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of reactive oxygen species produced as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:15355 acetylcholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15355 OBO:go/extensions/ro_pending#alters_location_of obsolete alters location of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/go/extensions/ro_pending#alters_location_of CHEBI:15354 choline biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15354 GO:0052575 carbohydrate localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052575 carbohydrate localisation Any process in which a carbohydrate is transported to, or maintained in, a specific location. Carbohydrates are any of a group of organic compounds based of the general formula Cx(H2O)y. GO:0052574 UDP-galactose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052574 uridine diphosphate galactose biosynthetic process|uridine diphosphate galactose biosynthesis|UDP-D-galactopyranose biosynthesis|UDP-D-galactopyranose biosynthetic process|UDP-D-galactose biosynthetic process|UDP-D-galactose biosynthesis|UDP-galactose biosynthesis The chemical reactions and pathways resulting in the formation of UDP-D-galactose, a substance composed of D-galactose in glycosidic linkage with guanosine diphosphate. UBERON:0007128 glomeral mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007128 corpuscle|glomerulus Portion of tissue that consists of the precursors of the pronephric glomus or glomerulus; derived from the medial portion of the pronephric intermediate mesoderm. GO:0052573 UDP-D-galactose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052573 UDP-galactose metabolism|UDP-D-galactopyranose metabolic process|uridine diphosphate galactose metabolism|uridine diphosphate galactose metabolic process|UDP-D-galactopyranose metabolism|UDP-D-galactose metabolism|UDP-galactose metabolic process The chemical reactions and pathways involving UDP-D-galactose, a substance composed of D-galactose in glycosidic linkage with guanosine diphosphate. CHEBI:15351 acetyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15351 CHEBI:15350 acetyl dihydrogen phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15350 GO:0052572 response to host immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052572 response to immune response of other organism involved in symbiotic interaction Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052589 malate dehydrogenase (menaquinone) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052589 EC:1.1.5.4|MetaCyc:RXNI-3 (S)-malate:(menaquinone) oxidoreductase activity|(S)-malate:menaquinone oxidoreductase activity Catalysis of the reaction: (S)-malate + a menaquinone = oxaloacetate + a menaquinol. GO:0052588 diacetyl reductase ((S)-acetoin forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052588 EC:1.1.1.304|RHEA:27286|KEGG_REACTION:R09078|MetaCyc:RXN-11032 (S)-acetoin dehydrogenase activity Catalysis of the reaction: (S)-acetoin + NAD(+) = diacetyl + H(+) + NADH. CHEBI:15391 (-)-bisdechlorogeodin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15391 GO:0052587 diacetyl reductase ((R)-acetoin forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052587 RHEA:22900|KEGG_REACTION:R02855|EC:1.1.1.303|MetaCyc:RXN-11036 (R)-acetoin dehydrogenase activity Catalysis of the reaction: (R)-acetoin + NAD(+) = diacetyl + H(+) + NADH. CHEBI:15390 (+)-bisdechlorogeodin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15390 CHEBI:29998 D-serine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29998 CHEBI:30985 4,4'-bipyridine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30985 CHEBI:30984 evernitrose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30984 CHEBI:29999 L-serine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29999 CHEBI:29994 D-aspartate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29994 CHEBI:29993 L-aspartate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29993 CHEBI:29995 aspartate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29995 CHEBI:29990 D-aspartate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29990 CHEBI:29991 L-aspartate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29991 GO:1904101 response to acadesine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904101 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acadesine stimulus. CHEBI:39317 growth regulator biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39317 GO:1904100 positive regulation of protein O-linked glycosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904100 up regulation of protein amino acid O-linked glycosylation|upregulation of protein O-linked glycosylation|positive regulation of protein amino acid O-linked glycosylation|activation of protein amino acid O-linked glycosylation|up-regulation of protein O-linked glycosylation|activation of protein O-linked glycosylation|up-regulation of protein amino acid O-linked glycosylation|upregulation of protein amino acid O-linked glycosylation|up regulation of protein O-linked glycosylation Any process that activates or increases the frequency, rate or extent of protein O-linked glycosylation. CHEBI:15389 (-)-trans-carveol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15389 GO:0052582 (+)-menthofuran synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052582 RHEA:25658|KEGG_REACTION:R08923|MetaCyc:1.14.13.104-RXN|EC:1.14.14.143 cytochrome P450 menthofuran synthase activity|(+)-MFS activity|(+)-pulegone 9-hydroxylase activity|(+)-pulegone,NADPH:oxygen oxidoreductase (9-hydroxylating) activity|menthofuran synthase activity Catalysis of the reaction: (R)-pulegone + H(+) + NADPH + O(2) = (R)-menthofuran + 2 H(2)O + NADP(+). CHEBI:15386 (3S,4R)-3,4-dihydrophenanthrene-3,4-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15386 CHEBI:15385 (+)-delta-cadinene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15385 GO:0052581 (-)-isopiperitenone reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052581 KEGG_REACTION:R06417|MetaCyc:RXN-5161|EC:1.3.1.82|RHEA:25651 (+)-cis-isopulegone:NADP+ oxidoreductase activity Catalysis of the reaction: (6R)-isoperitenone + H(+) + NADPH = (2R,5R)-isopulegone + NADP(+). GO:0052580 (+)-pulegone reductase, (-)-menthone as substrate, activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052580 EC:1.3.1.81|MetaCyc:RXN-5164 (-)-menthone:NADP+ oxidoreductase activity Catalysis of the reaction: (-)-menthone + NADP+ = (+)-pulegone + NADPH + H+. CHEBI:15388 (+)-trans-carveol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15388 UBERON:0007119 neck of femur biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007119 neck of the femur|femur neck|femoral neck|collum femoris The femur neck or neck of the femur is a flattened pyramidal process of bone, connecting the femoral head with the femoral shaft, and forming with the latter a wide angle opening medialward. CHEBI:15387 (+)-cis-sabinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15387 GO:0052586 oxidoreductase activity, acting on other nitrogenous compounds as donors, with a quinone or similar compound as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052586 EC:1.7.5.- Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces a quinone or similar compound. CHEBI:15382 (4R)-limonene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15382 GO:0052585 oxidoreductase activity, acting on the CH-NH2 group of donors, with a quinone or similar compound as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052585 EC:1.4.5.- Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a quinone or similar compound. GO:0052584 obsolete oxidoreductase activity, acting on halogen in donors, with NAD or NADP as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052584 EC:1.22.1.- OBSOLETE. Catalysis of an oxidation-reduction in which a halogen in the donor substance acts as a hydrogen or electron donor and reduces NAD or NADP. CHEBI:15384 limonene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15384 GO:0052583 obsolete oxidoreductase activity, acting on halogen in donors biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052583 EC:1.22.-.- OBSOLETE. Catalysis of an oxidation-reduction in which a halogen in the donor substance acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. CHEBI:15383 (4S)-limonene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15383 GO:0052599 methylputrescine oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052599 MetaCyc:RXN-8244|EC:1.4.3.22|KEGG_REACTION:R05334 N-methylputrescine:oxygen oxidoreductase (deaminating) activity Catalysis of the reaction: N-methylputrescine + H2O + O2 = N-methylaminobutanal + NH3 + hydrogen peroxide + H+. CHEBI:15380 succinyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15380 GO:0052598 histamine oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052598 MetaCyc:RXN-9600|RHEA:25625|EC:1.4.3.22|Reactome:R-HSA-5696131|KEGG_REACTION:R02150 1H-Imidazole-4-ethanamine:oxygen oxidoreductase (deaminating) activity|histamine:oxygen oxidoreductase (deaminating) activity|1H-Imidazole-4-ethanamine oxidase activity Catalysis of the reaction: histamine + H2O + O2 = imidazole-4-acetaldehyde + NH3 + hydrogen peroxide + H+. GO:1904109 positive regulation of cholesterol import biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904109 activation of cholesterol uptake|up regulation of cholesterol import|positive regulation of cholesterol uptake|up regulation of cholesterol uptake|upregulation of cholesterol import|upregulation of cholesterol uptake|up-regulation of cholesterol import|activation of cholesterol import|up-regulation of cholesterol uptake Any process that activates or increases the frequency, rate or extent of cholesterol import. GO:1904108 protein localization to ciliary inversin compartment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904108 protein localization in ciliary inversin compartment|protein localisation to ciliary inversin compartment|protein localisation in ciliary inversin compartment A process in which a protein is transported to, or maintained in, a location within a ciliary inversin compartment. GO:1904107 protein localization to microvillus membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904107 protein localisation in microvillus membrane|protein localization in microvillus membrane|protein localisation to microvillus membrane A process in which a protein is transported to, or maintained in, a location within a microvillus membrane. GO:1904106 protein localization to microvillus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904106 protein localisation to microvillus|protein localization in microvillus|protein localisation in microvillus A process in which a protein is transported to, or maintained in, a location within a microvillus. GO:1904105 positive regulation of convergent extension involved in gastrulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904105 up regulation of convergent extension involved in gastrulation|activation of convergent extension involved in gastrulation|up-regulation of convergent extension involved in gastrulation|upregulation of convergent extension involved in gastrulation Any process that activates or increases the frequency, rate or extent of convergent extension involved in gastrulation. GO:1904104 negative regulation of convergent extension involved in gastrulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904104 down regulation of convergent extension involved in gastrulation|downregulation of convergent extension involved in gastrulation|down-regulation of convergent extension involved in gastrulation|inhibition of convergent extension involved in gastrulation Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in gastrulation. GO:1904103 regulation of convergent extension involved in gastrulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904103 Any process that modulates the frequency, rate or extent of convergent extension involved in gastrulation. GO:1904102 cellular response to acadesine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904102 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acadesine stimulus. GO:1904112 positive regulation of plus-end directed microfilament motor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904112 up regulation of barbed-end directed actin-filament motor activity|upregulation of plus-end directed actin-filament motor activity|activation of barbed-end directed actin-filament motor activity|positive regulation of barbed-end directed actin-filament motor activity|up regulation of plus-end directed actin filament motor activity|positive regulation of plus-end directed actin filament motor activity|up regulation of plus-end directed microfilament motor activity|activation of plus-end directed actin filament motor activity|up regulation of plus-end directed actin-filament motor activity|up-regulation of barbed-end directed actin-filament motor activity|positive regulation of plus-end directed actin-filament motor activity|activation of plus-end directed actin-filament motor activity|up-regulation of plus-end directed actin filament motor activity|upregulation of plus-end directed microfilament motor activity|upregulation of barbed-end directed actin-filament motor activity|up-regulation of plus-end directed actin-filament motor activity|upregulation of plus-end directed actin filament motor activity|up-regulation of plus-end directed microfilament motor activity|activation of plus-end directed microfilament motor activity Any process that activates or increases the frequency, rate or extent of plus-end directed microfilament motor activity. GO:1904111 negative regulation of plus-end directed microfilament motor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904111 downregulation of plus-end directed actin filament motor activity|down-regulation of plus-end directed microfilament motor activity|down regulation of plus-end directed actin-filament motor activity|down-regulation of barbed-end directed actin-filament motor activity|negative regulation of barbed-end directed actin-filament motor activity|down-regulation of plus-end directed actin filament motor activity|downregulation of plus-end directed actin-filament motor activity|negative regulation of plus-end directed actin filament motor activity|inhibition of barbed-end directed actin-filament motor activity|downregulation of plus-end directed microfilament motor activity|down regulation of plus-end directed microfilament motor activity|negative regulation of plus-end directed actin-filament motor activity|inhibition of plus-end directed microfilament motor activity|down-regulation of plus-end directed actin-filament motor activity|inhibition of plus-end directed actin filament motor activity|inhibition of plus-end directed actin-filament motor activity|down regulation of barbed-end directed actin-filament motor activity|down regulation of plus-end directed actin filament motor activity|downregulation of barbed-end directed actin-filament motor activity Any process that stops, prevents or reduces the frequency, rate or extent of plus-end directed microfilament motor activity. GO:1904110 regulation of plus-end directed microfilament motor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904110 regulation of plus-end directed actin-filament motor activity|regulation of barbed-end directed actin-filament motor activity|regulation of plus-end directed actin filament motor activity Any process that modulates the frequency, rate or extent of plus-end directed microfilament motor activity. UBERON:0007100 primary circulatory organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007100 adult heart|dorsal tube|heart A hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood or analogs[GO,modified]. CHEBI:15379 dioxygen biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15379 CHEBI:15378 hydron biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15378 CHEBI:40303 lovastatin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_40303 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052593 MetaCyc:RXN-1401|EC:1.4.3.21|KEGG_REACTION:R02173 Catalysis of the reaction: tryptamine + H2O + O2 = NH3 + indole acetaldehyde + hydrogen peroxide + H+. CHEBI:15375 D-erythro-7,8-dihydrobiopterin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15375 CHEBI:15374 4a-hydroxytetrahydrobiopterin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15374 GO:0052592 oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052592 EC:1.17.7.- oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulphur protein as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces an iron-sulfur protein. GO:0052591 sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052591 MetaCyc:GLYC3PDEHYDROG-RXN|RHEA:28751|EC:1.1.5.3 Catalysis of the reaction: sn-glycerol 3-phosphate + ubiquinone-8 = glycerone phosphate + ubiquinol-8. CHEBI:15377 water biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15377 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052590 MetaCyc:RXN0-5258|EC:1.1.5.3 Catalysis of the reaction: sn-glycerol 3-phosphate + a ubiquinone = glycerone phosphate + a ubiquinol. GO:0052597 diamine oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052597 MetaCyc:RXN-9599|EC:1.4.3.22 diamine:oxygen oxidoreductase (deaminating) activity Catalysis of the reaction: a diamine + H2O + O2 = a monoamine + NH3 + hydrogen peroxide. CHEBI:15371 3-oxopristanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15371 GO:0052596 phenethylamine:oxygen oxidoreductase (deaminating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052596 MetaCyc:AMINEPHEN-RXN|KEGG_REACTION:R02613|EC:1.4.3.21|RHEA:25265 Catalysis of the reaction: phenylethylamine + O2 + H2O = phenylacetaldehyde + NH3 + hydrogen peroxide + H+. UBERON:0007106 chorionic villus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007106 villous chorion|embryonic placenta|placental villus|villous of placenta|chorionic villus|embryonic part of placenta|fetal placenta|chorionic villous|placental villous|chorionic villi|fetal part of placenta|placental villi One of the minute vascular projections of the fetal chorion that combines with maternal uterine tissue to form the placenta. CHEBI:15373 biopterin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15373 GO:0052595 aliphatic-amine oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052595 EC:1.4.3.21|RHEA:16153|MetaCyc:AMINEOXID-RXN aliphatic-amine:oxygen oxidoreductase(deaminating) activity Catalysis of the reaction: an aliphatic amine + H2O + O2 = an aldehyde + NH3 + hydrogen peroxide + H+. GO:0052594 aminoacetone:oxygen oxidoreductase(deaminating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052594 KEGG_REACTION:R02529|MetaCyc:AMACETOXID-RXN|EC:1.4.3.21|RHEA:28186 Catalysis of the reaction: aminoacetone + H2O + O2 = methylglyoxal + NH3 + hydrogen peroxide + H+. CHEBI:15372 5,6,7,8-tetrahydrobiopterin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15372 CHEBI:29979 L-histidine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29979 CHEBI:30968 azetidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30968 CHEBI:29976 D-tyrosine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29976 UBERON:0007172 angle of scapula biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007172 scapular angle CHEBI:29972 L-glutamic acid residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29972 GO:1904119 negative regulation of otic vesicle morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904119 inhibition of otic vesicle morphogenesis|down-regulation of otic vesicle morphogenesis|downregulation of otic vesicle morphogenesis|down regulation of otic vesicle morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of otic vesicle morphogenesis. UBERON:0007171 border of scapula biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007171 scapular border GO:1904118 regulation of otic vesicle morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904118 Any process that modulates the frequency, rate or extent of otic vesicle morphogenesis. CHEBI:29974 D-glutamate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29974 GO:1904117 cellular response to vasopressin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904117 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vasopressin stimulus. CHEBI:29973 L-glutamate residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29973 GO:1904116 response to vasopressin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904116 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vasopressin stimulus. GO:1904115 axon cytoplasm biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1904115 axoplasm Any cytoplasm that is part of a axon. GO:1904114 positive regulation of muscle filament sliding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904114 up regulation of muscle filament sliding|activation of muscle filament sliding|up-regulation of muscle filament sliding|upregulation of muscle filament sliding Any process that activates or increases the frequency, rate or extent of muscle filament sliding. CHEBI:29970 D-lysinium residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29970 GO:1904113 negative regulation of muscle filament sliding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904113 down regulation of muscle filament sliding|downregulation of muscle filament sliding|down-regulation of muscle filament sliding|inhibition of muscle filament sliding Any process that stops, prevents or reduces the frequency, rate or extent of muscle filament sliding. GO:1904123 positive regulation of fatty acid beta-oxidation by serotonin receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904123 up-regulation of fatty acid beta-oxidation by serotonin receptor signaling pathway|upregulation of fatty acid beta-oxidation by serotonin receptor signaling pathway|up regulation of fatty acid beta-oxidation by serotonin receptor signaling pathway|activation of fatty acid beta-oxidation by serotonin receptor signaling pathway|stimulation of fatty acid beta-oxidation by serotonin receptor signaling pathway A serotonin receptor signaling pathway that results in positive regulation of fatty acid beta-oxidation. GO:1904122 positive regulation of fatty acid beta-oxidation by octopamine signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904122 up-regulation of fatty acid beta-oxidation by octopamine signaling pathway|upregulation of fatty acid beta-oxidation by octopamine signaling pathway|up regulation of fatty acid beta-oxidation by octopamine signaling pathway|activation of fatty acid beta-oxidation by octopamine signaling pathway|stimulation of fatty acid beta-oxidation by octopamine signaling pathway An octopamine signaling pathway that results in positive regulation of fatty acid beta-oxidation. GO:1904121 phosphatidylethanolamine transfer activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1904121 intermembrane phosphatidylethanolamine transfer activity|phosphatidylethanolamine carrier activity|phosphatidylethanolamine transporter activity Removes phosphatidylethanolamine from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. GO:1904120 positive regulation of otic vesicle morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904120 up regulation of otic vesicle morphogenesis|upregulation of otic vesicle morphogenesis|up-regulation of otic vesicle morphogenesis|activation of otic vesicle morphogenesis Any process that activates or increases the frequency, rate or extent of otic vesicle morphogenesis. UBERON:0007177 lamina propria of mucosa of colon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007177 lamina propria of colonic mucosa|colonic lamina propria|lamina propria mucosae of colon|lamina propria of colonic mucous membrane A lamina propria that is part of a colonic mucosa. UBERON:0007175 inferior angle of scapula biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007175 angulus inferior (scapula)|angulus inferior scapulae An angle of the scapula formed by the union of the vertebral and axillary borders; its dorsal surface affords attachment to the Teres major and frequently to a few fibers of the Latissimus dorsi.[WP,unvetted] UBERON:0007174 medial border of scapula biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007174 vertebral border|medial part of scapula|margo medialis (scapula)|vertebral border of the scapula|margo medialis scapulae|medial border of the scapula|medial margin of the scapula|vertebral border of scapula The medial border of the scapula (vertebral border, medial margin) is the longest of the three borders, and extends from the medial to the inferior angle. It is arched, intermediate in thickness between the superior and the axillary borders, and the portion of it above the spine forms an obtuse angle with the part below. This border presents an anterior and a posterior lip, and an intermediate narrow area. The anterior lip affords attachment to the Serratus anterior; the posterior lip, to the Supraspinatus above the spine, the Infraspinatus below; the area between the two lips, to the Levator scapulC& above the triangular surface at the commencement of the spine, to the Rhomboideus minor on the edge of that surface, and to the Rhomboideus major below it; this last is attached by means of a fibrous arch, connected above to the lower part of the triangular surface at the base of the spine, and below to the lower part of the border. UBERON:0007173 lateral border of scapula biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007173 lateral part of scapula|margo lateralis scapulae|margo lateralis (scapula)|lateral border of scapula|axillary border of scapula The lateral border (or axillary border, or margin) is the thickest of the three borders of the scapula. It begins above at the lower margin of the glenoid cavity, and inclines obliquely downward and backward to the inferior angle. Immediately below the glenoid cavity is a rough impression, the infraglenoid tuberosity, about 2.5 cm. in length, which gives origin to the long head of the Triceps brachii; in front of this is a longitudinal groove, which extends as far as the lower third of this border, and affords origin to part of the Subscapularis. The inferior third is thin and sharp, and serves for the attachment of a few fibers of the Teres major behind, and of the Subscapularis in front. CHEBI:30960 5-pyridoxate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30960 CHEBI:29987 glutamate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29987 CHEBI:29986 D-glutamate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29986 CHEBI:29989 D-glutamate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29989 CHEBI:29988 L-glutamate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29988 CHEBI:29982 L-histidinium residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29982 GO:1904129 positive regulation of convergent extension involved in somitogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904129 up regulation of convergent extension involved in somitogenesis|upregulation of convergent extension involved in somitogenesis|up-regulation of convergent extension involved in somitogenesis|activation of convergent extension involved in somitogenesis Any process that activates or increases the frequency, rate or extent of convergent extension involved in somitogenesis. CHEBI:29985 L-glutamate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29985 GO:1904128 negative regulation of convergent extension involved in somitogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904128 downregulation of convergent extension involved in somitogenesis|down regulation of convergent extension involved in somitogenesis|inhibition of convergent extension involved in somitogenesis|down-regulation of convergent extension involved in somitogenesis Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in somitogenesis. CHEBI:29984 D-methionine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29984 GO:1904127 regulation of convergent extension involved in somitogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904127 Any process that modulates the frequency, rate or extent of convergent extension involved in somitogenesis. GO:1904126 convergent extension involved in notochord morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904126 Any convergent extension that is involved in notochord morphogenesis. CHEBI:29981 D-histidinium residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29981 GO:1904125 convergent extension involved in rhombomere morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904125 Any convergent extension that is involved in rhombomere morphogenesis. GO:1904124 microglial cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904124 The orderly movement of a microglial cell from one site to another. CHEBI:29980 D-histidine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29980 GO:1904134 negative regulation of convergent extension involved in rhombomere morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904134 down regulation of convergent extension involved in rhombomere morphogenesis|downregulation of convergent extension involved in rhombomere morphogenesis|down-regulation of convergent extension involved in rhombomere morphogenesis|inhibition of convergent extension involved in rhombomere morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in rhombomere morphogenesis. CHEBI:39306 pyrimidodiazepine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39306 GO:1904133 regulation of convergent extension involved in rhombomere morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904133 Any process that modulates the frequency, rate or extent of convergent extension involved in rhombomere morphogenesis. CHEBI:39305 imidazodiazepine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39305 GO:1904132 positive regulation of convergent extension involved in neural plate elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904132 up regulation of convergent extension involved in neural plate elongation|upregulation of convergent extension involved in neural plate elongation|up-regulation of convergent extension involved in neural plate elongation|activation of convergent extension involved in neural plate elongation Any process that activates or increases the frequency, rate or extent of convergent extension involved in neural plate elongation. CHEBI:39304 coformycins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39304 GO:1904131 negative regulation of convergent extension involved in neural plate elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904131 down-regulation of convergent extension involved in neural plate elongation|downregulation of convergent extension involved in neural plate elongation|down regulation of convergent extension involved in neural plate elongation|inhibition of convergent extension involved in neural plate elongation Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in neural plate elongation. CHEBI:15318 xanthine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15318 GO:1904130 regulation of convergent extension involved in neural plate elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904130 Any process that modulates the frequency, rate or extent of convergent extension involved in neural plate elongation. CHEBI:39308 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39308 CHEBI:29958 L-aspartic acid residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29958 CHEBI:29959 quinolinate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29959 CHEBI:30944 ascarylose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30944 CHEBI:30943 tyvelose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30943 CHEBI:29953 D-arginine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29953 CHEBI:29950 L-cysteine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29950 CHEBI:29952 L-arginine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29952 GO:1904139 regulation of microglial cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904139 Any process that modulates the frequency, rate or extent of microglial cell migration. CHEBI:29951 D-cysteine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29951 GO:1904138 positive regulation of convergent extension involved in notochord morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904138 up regulation of convergent extension involved in notochord morphogenesis|upregulation of convergent extension involved in notochord morphogenesis|up-regulation of convergent extension involved in notochord morphogenesis|activation of convergent extension involved in notochord morphogenesis Any process that activates or increases the frequency, rate or extent of convergent extension involved in notochord morphogenesis. GO:1904137 negative regulation of convergent extension involved in notochord morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904137 down-regulation of convergent extension involved in notochord morphogenesis|downregulation of convergent extension involved in notochord morphogenesis|down regulation of convergent extension involved in notochord morphogenesis|inhibition of convergent extension involved in notochord morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in notochord morphogenesis. GO:1904136 regulation of convergent extension involved in notochord morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904136 Any process that modulates the frequency, rate or extent of convergent extension involved in notochord morphogenesis. GO:1904135 positive regulation of convergent extension involved in rhombomere morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904135 upregulation of convergent extension involved in rhombomere morphogenesis|up regulation of convergent extension involved in rhombomere morphogenesis|activation of convergent extension involved in rhombomere morphogenesis|up-regulation of convergent extension involved in rhombomere morphogenesis Any process that activates or increases the frequency, rate or extent of convergent extension involved in rhombomere morphogenesis. UBERON:0007158 lumen of anal canal biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007158 anal canal lumen An anatomical cavity that surrounded_by a anal canal. GO:1904145 negative regulation of meiotic cell cycle process involved in oocyte maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904145 downregulation of meiotic cell cycle process involved in oocyte maturation|down regulation of meiotic cell cycle process involved in oocyte maturation|inhibition of meiotic cell cycle process involved in oocyte maturation|down-regulation of meiotic cell cycle process involved in oocyte maturation Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation. GO:1904144 phosphatidylinositol phosphate phosphatase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1904144 prostatic acid phosphatase complex A protein complex which is capable of phosphatidylinositol phosphate phosphatase activity. CHEBI:15349 acetone oxime biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15349 GO:1904143 positive regulation of carotenoid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904143 upregulation of carotenoid anabolism|up regulation of carotenoid biosynthetic process|up regulation of carotenoid biosynthesis|activation of carotenoid biosynthesis|activation of carotenoid biosynthetic process|upregulation of carotenoid synthesis|positive regulation of carotenoid biosynthesis|upregulation of carotenoid formation|up-regulation of carotenoid anabolism|activation of carotenoid anabolism|up-regulation of carotenoid synthesis|activation of carotenoid synthesis|up-regulation of carotenoid biosynthetic process|up-regulation of carotenoid biosynthesis|up-regulation of carotenoid formation|activation of carotenoid formation|positive regulation of carotenoid anabolism|up regulation of carotenoid anabolism|upregulation of carotenoid biosynthesis|upregulation of carotenoid biosynthetic process|positive regulation of carotenoid synthesis|up regulation of carotenoid synthesis|positive regulation of carotenoid formation|up regulation of carotenoid formation Any process that activates or increases the frequency, rate or extent of carotenoid biosynthetic process. GO:1904142 negative regulation of carotenoid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904142 down regulation of carotenoid synthesis|inhibition of carotenoid synthesis|down regulation of carotenoid formation|inhibition of carotenoid formation|negative regulation of carotenoid biosynthesis|down-regulation of carotenoid biosynthesis|down-regulation of carotenoid biosynthetic process|inhibition of carotenoid biosynthetic process|inhibition of carotenoid biosynthesis|down-regulation of carotenoid anabolism|negative regulation of carotenoid anabolism|down-regulation of carotenoid synthesis|negative regulation of carotenoid synthesis|down-regulation of carotenoid formation|negative regulation of carotenoid formation|downregulation of carotenoid anabolism|down regulation of carotenoid biosynthetic process|down regulation of carotenoid biosynthesis|down regulation of carotenoid anabolism|downregulation of carotenoid synthesis|downregulation of carotenoid biosynthesis|inhibition of carotenoid anabolism|downregulation of carotenoid biosynthetic process|downregulation of carotenoid formation Any process that stops, prevents or reduces the frequency, rate or extent of carotenoid biosynthetic process. GO:1904141 positive regulation of microglial cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904141 up regulation of microglial cell migration|activation of microglial cell migration|up-regulation of microglial cell migration|upregulation of microglial cell migration Any process that activates or increases the frequency, rate or extent of microglial cell migration. CHEBI:15346 coenzyme A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15346 GO:1904140 negative regulation of microglial cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904140 down-regulation of microglial cell migration|inhibition of microglial cell migration|down regulation of microglial cell migration|downregulation of microglial cell migration Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell migration. CHEBI:15345 acetoacetyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15345 CHEBI:15348 2-hydroxy-2-methylpropanenitrile biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15348 CHEBI:15347 acetone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15347 UBERON:0007151 mitral valve leaflet biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007151 mitral valve leaflets|leaflet of mitral valve|mitral valvular leaflet|mitral valve leaflet A valve leafleft that is part of a mitral valve. CHEBI:15342 acenaphthoquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15342 CHEBI:15341 beta-D-glucosiduronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15341 CHEBI:15344 acetoacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15344 CHEBI:15343 acetaldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15343 UBERON:0007159 lumen of colon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007159 colonic lumen|colon lumen An anatomical cavity that surrounded_by a colon. CHEBI:29969 L-lysinium residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29969 CHEBI:29968 D-lysine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29968 CHEBI:29965 L-argininium residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29965 CHEBI:29964 L-cysteinate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29964 CHEBI:29967 L-lysine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29967 CHEBI:29966 D-argininium residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29966 CHEBI:29961 L-aspartate residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29961 CHEBI:29963 D-cysteinate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29963 CHEBI:29962 D-aspartate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29962 GO:1904149 regulation of microglial cell mediated cytotoxicity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904149 Any process that modulates the frequency, rate or extent of microglial cell mediated cytotoxicity. GO:1904148 cellular response to nonylphenol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904148 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonylphenol stimulus. GO:1904147 response to nonylphenol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904147 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonylphenol stimulus. GO:1904146 positive regulation of meiotic cell cycle process involved in oocyte maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904146 up regulation of meiotic cell cycle process involved in oocyte maturation|upregulation of meiotic cell cycle process involved in oocyte maturation|up-regulation of meiotic cell cycle process involved in oocyte maturation|activation of meiotic cell cycle process involved in oocyte maturation Any process that activates or increases the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation. CHEBI:30959 4-pyridoxate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30959 GO:1904156 DN3 thymocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904156 The process in which a relatively unspecialized cell acquires the specialized features of a DN3 thymocyte. A DN3 thymocyte is a CD4-,CD8- thymocyte that is also CD44+,CD25+. UBERON:0007147 lumen of midgut biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007147 midgut lumen An anatomical cavity that surrounded_by a midgut. CHEBI:15339 acceptor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15339 GO:1904155 DN2 thymocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904155 The process in which a relatively unspecialized cell acquires the specialized features of a DN2 thymocyte. A DN2 thymocyte is a CD4-,CD8- thymocyte that is also CD44+,CD25-. GO:1904154 positive regulation of retrograde protein transport, ER to cytosol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904154 up regulation of retrograde protein transport, endoplasmic reticulum to cytosol|up regulation of retrograde protein transport, ER to cytosol|upregulation of protein dislocation from ER|activation of retrograde protein transport, ER to cytosol|positive regulation of protein retrotranslocation from ER|upregulation of retrograde protein transport, endoplasmic reticulum to cytosol|up regulation of protein dislocation from ER|up-regulation of retrograde protein transport, ER to cytosol|positive regulation of protein dislocation from ER|activation of protein dislocation from ER|up-regulation of retrograde protein transport, endoplasmic reticulum to cytosol|activation of retrograde protein transport, endoplasmic reticulum to cytosol|upregulation of retrograde protein transport, ER to cytosol|up-regulation of protein dislocation from ER|up-regulation of protein retrotranslocation from ER|positive regulation of retrograde protein transport, endoplasmic reticulum to cytosol Any process that activates or increases the frequency, rate or extent of retrograde protein transport, ER to cytosol. GO:1904153 negative regulation of retrograde protein transport, ER to cytosol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904153 negative regulation of protein retrotranslocation from ER|downregulation of retrograde protein transport, endoplasmic reticulum to cytosol|down regulation of protein dislocation from ER|down-regulation of retrograde protein transport, ER to cytosol|down regulation of retrograde protein transport, endoplasmic reticulum to cytosol|inhibition of retrograde protein transport, endoplasmic reticulum to cytosol|downregulation of protein dislocation from ER|inhibition of retrograde protein transport, ER to cytosol|down-regulation of protein dislocation from ER|negative regulation of protein dislocation from ER|inhibition of protein dislocation from ER|down regulation of retrograde protein transport, ER to cytosol|down-regulation of retrograde protein transport, endoplasmic reticulum to cytosol|negative regulation of retrograde protein transport, endoplasmic reticulum to cytosol|downregulation of retrograde protein transport, ER to cytosol Any process that stops, prevents or reduces the frequency, rate or extent of retrograde protein transport, ER to cytosol. UBERON:0007144 embryonic post-anal tail biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007144 embryonic tail|tail of embryo|embryo tail An embryonic structure that will either develop into a post-anal tail or recede into a vestigial remnant of the tail. GO:1904152 regulation of retrograde protein transport, ER to cytosol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904152 regulation of retrograde protein transport, endoplasmic reticulum to cytosol|regulation of protein dislocation from ER|regulation of protein retrotranslocation from ER Any process that modulates the frequency, rate or extent of retrograde protein transport, ER to cytosol. UBERON:0007143 right internal carotid artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007143 arteria carotis interna dextra An internal carotid artery that branching_part_of a right common carotid artery plus branches. CHEBI:15335 5,7-dihydroxy-4'-methoxyflavone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15335 UBERON:0007142 left internal carotid artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007142 arteria caritis interna sinistra An internal carotid artery that branching_part_of a left common carotid artery plus branches. GO:1904151 positive regulation of microglial cell mediated cytotoxicity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904151 up regulation of microglial cell mediated cytotoxicity|activation of microglial cell mediated cytotoxicity|up-regulation of microglial cell mediated cytotoxicity|upregulation of microglial cell mediated cytotoxicity Any process that activates or increases the frequency, rate or extent of microglial cell mediated cytotoxicity. CHEBI:15334 N(alpha)-methyl-L-tryptophan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15334 GO:1904150 negative regulation of microglial cell mediated cytotoxicity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904150 down-regulation of microglial cell mediated cytotoxicity|inhibition of microglial cell mediated cytotoxicity|down regulation of microglial cell mediated cytotoxicity|downregulation of microglial cell mediated cytotoxicity Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell mediated cytotoxicity. CHEBI:15337 beta-alanopine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15337 CHEBI:15333 zeatin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15333 UBERON:0007148 lumen of hindgut biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007148 hindgut lumen An anatomical cavity that surrounded_by a hindgut. CHEBI:64261 lupanine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64261 CHEBI:64260 aminodeoxyfutalosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64260 CHEBI:88230 autophagy inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88230 CHEBI:64265 (3R,6S)-6-hydroxy-3,7-dimethyloctanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64265 CHEBI:88232 epoxypheophorbide a(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88232 CHEBI:132008 5,10-dihydrophenazine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132008 CHEBI:88231 beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer(d18:1/18:0)(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88231 CHEBI:64264 3-isopropenyl-6-oxoheptanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64264 CHEBI:64263 5-guanidino-3-methyl-2-oxopentanoic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64263 CHEBI:88234 alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer(d18:1/18:0)(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88234 CHEBI:64262 17-hydroxylupanine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64262 CHEBI:88233 epoxypheophorbide a(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88233 CHEBI:64268 erythromycin A(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64268 CHEBI:88235 alpha-Neu5Ac-(2->3)-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer(d18:1/18:0)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88235 CHEBI:64267 5-methyltetrahydrosarcinapterin(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64267 CHEBI:88238 (5Z,9Z,12Z)-octadecatrienoyl-containing glycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88238 CHEBI:64266 tricyclene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64266 CHEBI:88237 CDP-3,6-dideoxy-alpha-D-mannose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88237 CHEBI:132001 cholesteryl octadecenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132001 CHEBI:88239 (5Z,9Z,12Z,15Z)-octadecatetraenoyl-containing glycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88239 CHEBI:132003 (10aS)-10,10a-dihydrophenazine-1-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132003 CHEBI:132002 cholesteryl octadecadienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132002 CHEBI:132005 (1R)-1,4,5,10-tetrahydrophenazine-1-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132005 CHEBI:132004 cholesteryl octadecatrienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132004 CHEBI:132007 cholesteryl icosapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132007 CHEBI:132006 cholesteryl icosatetraenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132006 PR:000016876 thymidylate synthase biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000016876 TS|thyA|TSase|TYMS A protein that is a translation product of the human TYMS gene or a 1:1 ortholog thereof. CHEBI:64272 tunicamycin D2 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64272 CHEBI:64271 tunicamycin D1 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64271 CHEBI:64270 cyclic dehypoxanthinylfutalosinate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64270 CHEBI:88221 N(omega),N('omega)-dimethyl-L-arginine(1+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88221 CHEBI:132019 16-HETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132019 CHEBI:64274 7-hydroxy-4-isopropenyl-7-methyloxepan-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64274 CHEBI:88222 N(5)-methyl-argininium(1+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88222 CHEBI:64273 erythromycin C biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64273 CHEBI:64279 erythromycin B(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64279 CHEBI:64278 Reactive Blue 5 quinol form(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64278 CHEBI:88226 (2E,6E)-farnesyl monophosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88226 CHEBI:64277 7,8-dihydrobiopterin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64277 CHEBI:88229 alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer(d18:1/18:0)(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88229 CHEBI:132012 S-hexanoyl-4'-phosphopantetheine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132012 CHEBI:88228 alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer(d18:1/18:0)(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88228 CHEBI:132011 S-butyryl-4'-phosphopantetheine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132011 CHEBI:132014 S-decanoyl-4'-phosphopantetheine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132014 CHEBI:132013 S-octanoyl-4'-phosphopantetheine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132013 CHEBI:132016 17-HETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132016 CHEBI:132015 S-dodecanoyl-4'-phosphopantetheine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132015 CHEBI:132018 S-hexadecanoyl-4'-phosphopantetheine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132018 CHEBI:132017 S-tetradecanoyl-4'-phosphopantetheine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132017 GO:0052502 obsolete positive regulation by host of defense-related symbiont MAP kinase-mediated signal transduction pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052502 activation by organism of defense-related symbiont MAP kinase-mediated signal transduction pathway|upregulation by host of defense-related symbiont MAP kinase-mediated signal transduction pathway|positive regulation by organism of defense-related symbiont mitogen-activated protein kinase-mediated signal transduction pathway|stimulation by host of defense-related symbiont MAP kinase-mediated signal transduction pathway|up-regulation by host of defense-related symbiont MAP kinase-mediated signal transduction pathway|activation by host of defense-related symbiont MAP kinase-mediated signal transduction pathway|upregulation by organism of defense-related symbiont MAP kinase-mediated signal transduction pathway|positive regulation by organism of defense-related symbiont MAPK-mediated signal transduction pathway|induction by organism of defense-related symbiont MAP kinase-mediated signal transduction pathway|up regulation by host of defense-related symbiont MAP kinase-mediated signal transduction pathway OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of symbiont MAP kinase-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052501 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052501 GO:0052500 obsolete positive regulation by organism of symbiont apoptosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052500 positive regulation by organism of symbiont apoptosis|positive regulation by organism of symbiont apoptotic programmed cell death OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the symbiont, where programmed cell death proceeds by apoptosis. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052506 obsolete positive regulation by organism of defense-related symbiont ethylene-mediated signal transduction pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052506 upregulation by organism of defense-related symbiont ethylene-mediated signal transduction pathway|induction by organism of defense-related symbiont ethylene-mediated signal transduction pathway|activation by organism of defense-related symbiont ethylene-mediated signal transduction pathway|positive regulation by organism of defense-related symbiont ethylene-mediated signal transduction pathway OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of symbiont ethylene-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:64283 copal-8-ol diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64283 CHEBI:88250 6-deoxy-6-sulfoglucono-1,5-lactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88250 GO:0052505 obsolete positive regulation by organism of defense-related symbiont cell wall callose deposition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052505 positive regulation by organism of defense-related symbiont cell wall callose deposition|induction by organism of defense-related symbiont cell wall callose deposition OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the deposition of callose by the symbiont in its cell walls, occurring as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:39282 iodomethane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_39282 CHEBI:64282 (Z)-biformene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64282 GO:0052504 obsolete positive regulation by organism of defense-related symbiont callose deposition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052504 induction by organism of defense-related symbiont callose deposition|positive regulation by organism of defense-related papilla formation in symbiont|positive regulation by organism of defense-related symbiont callose deposition|induction by organism of defense-related papilla formation in symbiont OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of callose deposition by the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. NCBITaxon:3027 Cryptophyceae organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_3027 Cryptophyta|Chromophyta|cryptomonads|cryptomonads|cryptophytes|algae|Cryptomonadida CHEBI:39281 fluoromethanes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39281 CHEBI:88252 (11Z,14Z)-icosadienoyl-containing glycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88252 GO:0052503 obsolete positive regulation by organism of defense-related symbiont calcium-dependent protein kinase pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052503 positive regulation of defense-related symbiont CDPK pathway by organism|positive regulation by organism of defense-related symbiont calcium-dependent protein kinase pathway OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the symbiont calcium-dependent protein kinase pathway during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:88251 (9Z,11E,13E,15Z)-octadecatetraenoyl-containing glycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88251 CHEBI:64280 (E)-beta-ocimene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64280 CHEBI:64287 17-hydroxylupanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64287 CHEBI:88254 (9Z,11E,13E)-octadecatrienoyl-containing glycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88254 GO:0052509 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052509 CHEBI:88253 (11Z,14Z,17Z)-icosatrienoyl-containing glycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88253 CHEBI:64286 aminodeoxyfutalosinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64286 GO:0052508 obsolete positive regulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052508 positive regulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway|induction by organism of defense-related symbiont SA-mediated signal transduction pathway|upregulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway|induction by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway|activation by organism of defense-related symbiont SA-mediated signal transduction pathway|positive regulation by organism of defense-related symbiont SA-mediated signal transduction pathway|activation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway|upregulation by organism of defense-related symbiont SA-mediated signal transduction pathway OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of symbiont salicylic acid-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:64285 (-)-bornyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64285 GO:0052507 obsolete positive regulation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052507 induction by organism of defense-related symbiont SA-mediated signal transduction pathway|induction by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway|upregulation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway|activation by organism of defense-related symbiont SA-mediated signal transduction pathway|positive regulation by organism of defense-related symbiont SA-mediated signal transduction pathway|positive regulation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway|activation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway|upregulation by organism of defense-related symbiont SA-mediated signal transduction pathway OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of symbiont jasmonic acid-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:64284 1,4-dihydroxy-6-naphthoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64284 CHEBI:88257 (8E,10E,12Z)-octadecatrienoyl-containing glycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88257 CHEBI:64289 5-methyltetrahydrosarcinapterin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64289 CHEBI:88259 (9Z,11E,13Z)-octadeca-9,11,13-trienoyl-containing glycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88259 CHEBI:64288 5-guanidino-3-methyl-2-oxopentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64288 CHEBI:39276 fumigant biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39276 CHEBI:39275 bromomethane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_39275 CHEBI:39279 halomethane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39279 CHEBI:39278 bromomethanes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39278 CHEBI:39277 fumigant insecticide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39277 GO:0052513 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052513 CHEBI:64290 erythromycin cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64290 GO:0052512 obsolete positive regulation by organism of hormone or growth regulator levels in symbiont biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052512 positive regulation by organism of hormone or growth regulator levels in symbiont|positive modulation of hormone or growth regulator levels in symbiont OBSOLETE. The increase by an organism of the levels of hormones or growth regulators in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052511 obsolete positive regulation by organism of symbiont ethylene-mediated defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052511 induction by organism of symbiont ethylene-mediated defense response|upregulation by organism of symbiont ethylene-mediated defense response|activation by organism of symbiont ethylene-mediated defense response|positive regulation by organism of symbiont ethylene-mediated defense response OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the ethylene-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052510 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052510 GO:0052517 obsolete positive regulation by organism of symbiont non-apoptotic programmed cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052517 positive regulation by organism of symbiont non-apoptotic programmed cell death OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the symbiont, where programmed cell death proceeds by a non-apoptotic pathway. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:64294 7-ketocholesterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64294 GO:0052516 obsolete positive regulation by organism of symbiont jasmonic acid-mediated defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052516 induction by organism of symbiont jasmonic acid-mediated defense response|positive regulation by organism of symbiont JA-mediated defense response|induction by organism of symbiont JA-mediated defense response|positive regulation by organism of symbiont jasmonic acid-mediated defense response OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the jasmonic acid-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:64293 copal-8-ol diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64293 GO:0052515 obsolete positive regulation by organism of symbiont innate immunity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052515 positive regulation of symbiont innate immune response|positive regulation by organism of symbiont innate immunity OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the innate immune response of the symbiont organism; the innate immune response is the symbiont's first line of defense against infection. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:88241 (9Z,12E)-octadecadienoyl-containing glycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88241 CHEBI:64292 coniferyl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64292 GO:0052514 obsolete positive regulation by organism of symbiont inflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052514 positive regulation by organism of symbiont inflammatory response OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the inflammatory response of a symbiont organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:64291 Reactive Blue 5 quinol form biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64291 CHEBI:88240 oleoyl-containing glycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88240 CHEBI:64298 (-)-bornyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64298 CHEBI:88243 UDP-beta-L-iduronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88243 CHEBI:88242 (9Z,12Z)-octadeca-9,12-dien-6-ynoyl-containing glycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88242 GO:0052519 positive regulation by host of nutrient release from symbiont biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052519 upregulation by host of nutrient release from symbiont|stimulation by host of nutrient release from symbiont|up-regulation by host of nutrient release from symbiont|activation by host of nutrient release from symbiont|promotion of nutrient release from symbiont|up regulation by host of nutrient release from symbiont Any process in which an organism activates, maintains or increases the frequency, rate or extent of the release of nutrients from a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:88245 prenyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88245 CHEBI:88244 (9Z,12Z,15Z)-octadeca-9,12,15-trien-6-ynoyl-containing glycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88244 GO:0052518 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052518 CHEBI:88247 [5-(aminomethyl)-3-furyl]methyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88247 CHEBI:88248 (4-{4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88248 CHEBI:39284 iodomethanes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39284 GO:0052524 obsolete positive regulation by organism of symbiont salicylic acid-mediated defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052524 positive regulation by organism of symbiont SA-mediated defense response|induction by organism of symbiont salicylic acid-mediated defense response|induction by organism of symbiont SA-mediated defense response|positive regulation by organism of symbiont salicylic acid-mediated defense response OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the salicylic acid-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052523 obsolete positive regulation by organism of symbiont programmed cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052523 enhancement or induction of symbiont programmed cell death|positive regulation by organism of symbiont programmed cell death OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:88270 6-deoxy-6-sulfo-D-gluconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88270 GO:0052522 obsolete positive regulation by organism of phagocytosis in other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052522 upregulation by organism of phagocytosis in other organism during symbiotic interaction|positive regulation by organism of phagocytosis in other organism during symbiotic interaction|activation by organism of phagocytosis in other organism during symbiotic interaction|stimulation by organism of phagocytosis in other organism during symbiotic interaction|up regulation by organism of phagocytosis in other organism during symbiotic interaction|up-regulation by organism of phagocytosis in other organism during symbiotic interaction OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in the second organism, where the two organisms are in a symbiotic interaction. GO:0052521 obsolete positive regulation by host of symbiont phagocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052521 upregulation by host of symbiont phagocytosis|up regulation by host of symbiont phagocytosis|activation by host of symbiont phagocytosis|stimulation by host of symbiont phagocytosis|up-regulation by host of symbiont phagocytosis OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052528 obsolete upregulation by organism of symbiont programmed cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052528 upregulation by organism of symbiont programmed cell death|enhancement of symbiont programmed cell death by organism OBSOLETE. Any process by which an organism increases the frequency, rate or extent of programmed cell death in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052527 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052527 GO:0052526 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052526 GO:0052525 obsolete positive regulation by host of symbiont signal transduction pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052525 up-regulation by host of symbiont signal transduction pathway|activation by host of symbiont signal transduction pathway|up regulation by host of symbiont signal transduction pathway|upregulation by host of symbiont signal transduction pathway|stimulation by host of symbiont signal transduction pathway OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the symbiont signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:88278 N-acetylhexosaminyl-dihexosylceramide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88278 CHEBI:88277 alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88277 GO:0052529 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052529 UBERON:0007213 mesenchyme derived from head neural crest biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007213 head mesenchyme from cranial neural crest|head neural crest derived mesenchyme|head mesenchyme from neural crest Mesenchyme that develops_from a cranial neural crest. CHEBI:39259 pyrethroid ester acaricide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39259 CHEBI:39252 pyridophenoxazine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39252 GO:0052520 positive regulation by organism of nutrient release from other organism involved in symbiotic interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052520 up-regulation by organism of nutrient release from other organism during symbiotic interaction|promotion of nutrient release from other organism|upregulation by organism of nutrient release from other organism during symbiotic interaction|activation by organism of nutrient release from other organism during symbiotic interaction|positive regulation by organism of nutrient release from other organism during symbiotic interaction|up regulation by organism of nutrient release from other organism during symbiotic interaction|stimulation by organism of nutrient release from other organism during symbiotic interaction Any process in which an organism activates, maintains or increases the frequency, rate or extent of the release of nutrients from a second organism, where the two organisms are in a symbiotic interaction. CHEBI:39258 diphenyl ether biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_39258 UBERON:0007214 mesenchyme derived from trunk neural crest biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007214 trunk mesenchyme from neural crest|trunk neural crest derived mesenchyme Mesenchyme that develops_from a trunk neural crest. GO:0052535 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052535 GO:0052534 obsolete positive regulation by organism of induced systemic resistance in symbiont biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052534 positive regulation by organism of induced systemic resistance in symbiont OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of induced systemic resistance in the symbiont organism; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052533 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052533 GO:0052532 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052532 GO:0052539 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052539 CHEBI:88261 palmitoleoyl-containing glycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88261 GO:0052538 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052538 CHEBI:88260 (9Z)-octadec-9-en-12-ynoyl-containing glycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88260 CHEBI:39270 naphthofuran biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39270 GO:0052537 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052537 GO:0052536 obsolete positive regulation by organism of systemic acquired resistance in symbiont biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052536 positive regulation by organism of systemic acquired resistance in symbiont OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of systemic acquired resistance in the symbiont organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:88262 (9Z,12E)-hexadecadienoyl-containing glycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88262 CHEBI:88265 (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-containing glycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88265 CHEBI:88264 (7Z,10Z,13Z,16Z)-docosatetraenoyl-containing glycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88264 CHEBI:88267 (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-containing glycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88267 CHEBI:88266 (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-containing glycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88266 CHEBI:88269 (7Z,10Z,13Z)-hexadecatrienoyl-containing glycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88269 CHEBI:88268 (7Z,10Z)-hexadecadienoyl-containing glycerolipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88268 GO:0052531 obsolete positive regulation by organism of defense-related symbiont calcium ion flux biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052531 positive regulation by organism of defense-related symbiont calcium ion flux|positive regulation by organism of defense-related symbiont Ca2+ flux OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of fluxes of calcium ions that occur as part of the defense response of a host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052530 obsolete positive regulation by organism of symbiont resistance gene-dependent defense response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052530 positive regulation by organism of defense response in symbiont by specific elicitors|positive regulation by organism of symbiont resistance gene-dependent defense response|positive regulation by organism of pathogen-race/symbiont plant cultivar-specific resistance in symbiont|positive regulation by organism of symbiont gene-for-gene resistance OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the resistance gene-dependent defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:39268 dibenzothiazepine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39268 UBERON:0007204 brachiocephalic vasculature biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0007204 The vasculature consisting of brachiocephalic arteries and veins. GO:0052546 cell wall pectin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052546 cellulose and pectin-containing cell wall pectin metabolic process|pectin metabolism during cell wall biogenesis|plant-type cell wall pectin metabolic process|cell wall pectin metabolism The chemical reactions and pathways involving pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues, as part of the organization and biogenesis of the cell wall. GO:0052545 callose localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052545 callose localisation Any process in which callose is transported to, and/or maintained in, a specific location. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls. GO:0052544 defense response by callose deposition in cell wall biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052544 callose localization in cell wall during defense response|callose deposition in cell wall during defense response|cell wall callose localization during defense response|cell wall callose deposition during defense response Any process in which callose is transported to, and/or maintained in, the cell wall during the defense response. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls. CHEBI:88291 hydroxyimidazole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88291 GO:0052543 callose deposition in cell wall biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052543 callose localization in cell wall|cell wall callose localization|cell wall callose deposition Any process in which callose is transported to, and/or maintained in, the cell wall. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls. GO:0052549 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052549 GO:0052548 regulation of endopeptidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052548 protease regulator activity Any process that modulates the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins. GO:0052547 regulation of peptidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052547 peptidase regulator activity Any process that modulates the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins. CHEBI:39237 farnesene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39237 CHEBI:40235 9H-purine-2,6-diamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_40235 GO:0052542 defense response by callose deposition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052542 callose deposition during defense response|callose localization during defense response Any process in which callose is transported to, and/or maintained in, a specific location during the defense response. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls. CHEBI:39236 alpha-farnesene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_39236 GO:0052541 plant-type cell wall cellulose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052541 cell wall cellulose metabolism|cellulose and pectin-containing cell wall cellulose metabolic process The chemical reactions and pathways involving cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, as part of the organization and biogenesis of the cell wall. GO:0052540 obsolete positive regulation by organism of defense-related symbiont cell wall thickening biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052540 positive regulation by organism of defense-related symbiont cell wall thickening|positive regulation by organism of symbiont defensive cell wall thickening OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of symbiont processes resulting in the thickening of its cell walls, occurring as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052557 obsolete positive regulation by organism of symbiont immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052557 positive regulation by organism of symbiont immune response OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the immune response of the symbiont organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. GO:0052556 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052556 GO:0052555 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052555 GO:0052554 obsolete modulation by organism of symbiont immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052554 modulation by organism of symbiont immune response OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the immune response of the symbiont organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. CHEBI:39250 isopentadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39250 GO:0052559 induction by symbiont of host immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052559 positive regulation by symbiont of host immune response|up regulation by symbiont of host immune response|positive regulation by organism of immune response of other organism involved in symbiotic interaction|upregulation by symbiont of host immune response|up-regulation by symbiont of host immune response|induction by organism of immune response of other organism involved in symbiotic interaction|activation by symbiont of host immune response|stimulation by symbiont of host immune response Any process in which a symbiont activates the immune response of the host organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052558 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052558 CHEBI:39241 beta-farnesene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_39241 GO:0052553 modulation by symbiont of host immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052553 modulation by organism of immune response of other organism involved in symbiotic interaction Any process in which a symbiont modulates the frequency, rate or extent of the immune response of the host organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0052552 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052552 CHEBI:39246 nonadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39246 GO:0052551 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052551 GO:0052550 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052550 CHEBI:78826 O-(S-3-oxononanoylpantetheine-4'-phosphoryl)serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78826 CHEBI:78824 O-(S-3-oxoheptanoylpantetheine-4'-phosphoryl)serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78824 CHEBI:78823 O-(S-3-oxo-4-methylhexanoylpantetheine-4'-phosphoryl)serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78823 CHEBI:132090 O(3)-(beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-serine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132090 CHEBI:78827 O-[S-(3R)-3-hydroxyacylpantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78827 CHEBI:132088 O(3)-(beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-serine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132088 CHEBI:132081 17-oxoresolvin D1(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132081 CHEBI:132080 8-oxoresolvin D1(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132080 CHEBI:132083 18(S)-HEPE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132083 CHEBI:132085 O(3)-(beta-D-xylosyl)-L-serine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132085 CHEBI:78822 O-(S-3-oxo-5-methylhexanoylpantetheine-4'-phosphoryl)serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78822 CHEBI:132087 15(S)-HEPE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132087 CHEBI:78820 O-(S-3-oxo-4-methylpentanoylpantetheine-4'-phosphoryl)serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78820 CHEBI:78837 15(R)-HETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78837 CHEBI:78836 11(R)-HETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78836 CHEBI:132091 (5S)-hydroperoxy-(18S)-hydroxy-(6E,8Z,11Z,14Z,16E)-icosapentaenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132091 CHEBI:132093 O(3)-(beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132093 CHEBI:78833 11-HETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78833 CHEBI:78832 (5Z,8Z,11Z,13E)-15-HETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78832 CHEBI:78847 UDP-2,3-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78847 CHEBI:78846 O-(S-pimeloylpantetheine-4'-phosphoryl)serine(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78846 CHEBI:78845 O-[S-(methoxycarbonylacetyl)pantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78845 CHEBI:132067 (5S)-hydroperoxy-(14R,15S)-epoxy-(6E,8Z,11Z)-icosatrienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132067 CHEBI:156034 phosphatidylglycerol 38:3 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_156034 CHEBI:156033 phosphatidylglycerol 38:2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_156033 CHEBI:132066 S-(1-hydroxy-2-methylbut-3-en-2-yl)glutathione biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132066 CHEBI:132069 (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132069 CHEBI:156031 phosphatidylglycerol 40:6 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_156031 CHEBI:132068 (8S)-hydroperoxy-(14S,15R)-epoxy-(5Z,9E,11Z)-icosatrienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132068 CHEBI:156030 phosphatidylglycerol 40:5 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_156030 CHEBI:78840 olefinic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78840 CHEBI:132061 N-[12(S)-hydroperoxy-(5Z,8Z,10E,14Z)-icosatetraenoyl]taurine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132061 CHEBI:132060 N-arachidonoyltaurine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132060 CHEBI:156039 phosphatidylglycerol 44:12 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_156039 CHEBI:132063 (12S)-hydroperoxy-(14R,15S)-epoxy-(5Z,8Z,10E)-icosatrienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132063 CHEBI:78844 3'-(N-formyl-L-methionyl)adenylyl(1-) group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78844 CHEBI:132062 N-[15(S)-hydroperoxy-(5Z,8Z,11Z,13E)-icosatetraenoyl]taurine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132062 CHEBI:156037 phosphatidylglycerol 42:8 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_156037 CHEBI:132065 (12S)-hydroperoxy-(14S,15R)-epoxy-(5Z,8Z,10E)-icosatrienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132065 CHEBI:156036 phosphatidylglycerol 40:7 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_156036 CHEBI:132064 11-hydroxy-(12S,13S)-epoxy-(9Z)-octadecenoate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132064 CHEBI:156035 phosphatidylglycerol 38:5 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_156035 CHEBI:78859 12(S)-HPE(5,8,10)TrE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78859 CHEBI:78858 (R)-2-methylpyrrolidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78858 CHEBI:78856 2-methyl-1-pyrroline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78856 CHEBI:132078 N-[(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-icosatetraenoyl]-gamma-aminobutyrate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132078 CHEBI:132077 N-[(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-icosatetraenoyl]alaninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132077 CHEBI:132079 resolvin D1(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132079 CHEBI:132070 eoxin A4(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132070 CHEBI:132072 N-arachidonoyl-gamma-aminobutyrate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132072 CHEBI:156029 phosphatidylglycerol 38:6 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_156029 CHEBI:132071 N-arachidonoyl-L-alaninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132071 CHEBI:132074 N-[(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-icosatetraenoyl]alaninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132074 CHEBI:132073 N-[(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-icosatetraenoyl]glycinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132073 CHEBI:132076 N-[(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-icosatetraenoyl]glycinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132076 CHEBI:132075 N-[(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-icosatetraenoyl]-gamma-aminobutanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132075 CHEBI:78869 octacosapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78869 CHEBI:78868 octacosatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78868 CHEBI:78867 tetracosatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78867 CHEBI:64221 (3R,6S)-6-hydroxy-3,7-dimethyloctanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64221 CHEBI:64220 monosodium glutamate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64220 CHEBI:64225 (3R,6R)-6-hydroxy-3-isopropenylheptanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64225 CHEBI:64224 6-hydroxy-3-isopropenylheptanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64224 CHEBI:64223 6-hydroxy-3,7-dimethyloctanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64223 CHEBI:64229 6-isopropenyl-3-methyloxepan-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64229 CHEBI:132045 N-hexadecanoyltaurine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132045 CHEBI:132044 Deoxymethylsphingoid base biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132044 CHEBI:64228 tunicamycin A0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64228 CHEBI:132047 N-stearoyltaurine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132047 CHEBI:132046 Deoxysphingoid base biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132046 CHEBI:64226 (3S,6R)-6-hydroxy-3-isopropenylheptanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64226 CHEBI:132049 N-tetracosanoyltaurine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132049 CHEBI:132048 N-icosanoyltaurine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132048 CHEBI:78862 tetracosapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78862 CHEBI:78861 14(S)-HPDHE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78861 CHEBI:78860 12(S)-HPE(8,10,14)TrE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78860 CHEBI:78866 hexacosahexaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78866 CHEBI:132040 fatty acid-taurine conjugate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132040 CHEBI:78865 hexacosenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78865 CHEBI:78864 hexacosatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78864 CHEBI:132043 N-tetradecanoyltaurine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132043 CHEBI:132042 N-dodecanoyltaurine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132042 CHEBI:78863 hexacosapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78863 CHEBI:64232 (3S,6R)-6-isopropenyl-3-methyloxepan-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64232 CHEBI:64230 (3R,6S)-6-isopropenyl-3-methyloxepan-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64230 CHEBI:64236 (6E)-8-oxogeraniol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64236 CHEBI:64235 (6E)-8-hydroxygeraniol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64235 CHEBI:64234 3-isopropenyl-6-oxoheptanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64234 CHEBI:64239 (6E)-8-oxogeranial biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64239 CHEBI:64238 (6E)-8-hydroxygeranial biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64238 CHEBI:64237 EC 2.7.8.15 (UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64237 PR:000002201 dynein light chain biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000002201 A protein that is a translation product of the human DYNLL1 or DYNLL2 genes, or 1:1 orthologs thereof. The protein is small (89 residues in human and mouse) with core architecture consisting of a Dynein light chain type 1 domain (Pfam:PF01221). PR:000002204 lymphotoxin-alpha biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000002204 LT-alpha|LTA|TNFB|TNF-beta|TNFSF1|tumor necrosis factor B|tumor necrosis factor ligand superfamily member 1 A lymphotoxin that is a translation product of the human LTA gene or a 1:1 ortholog thereof. CHEBI:132052 (S)-demethyl-4-deoxygadusol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132052 CHEBI:64243 monosodium L-glutamate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64243 CHEBI:64241 (6R)-L-threo-tetrahydrobiopterin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64241 CHEBI:64240 L-threo-7,8-dihydrobiopterin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64240 CHEBI:64247 (3R,6R)-6-hydroxy-3-isopropenylheptanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64247 CHEBI:64246 tunicamycin A2 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64246 CHEBI:64245 tunicamycin A1 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64245 CHEBI:64244 monosodium D-glutamate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64244 CHEBI:132023 S-acyl-4'-phosphopantetheine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132023 CHEBI:132022 12-hydroxyjasmonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132022 CHEBI:132025 21-HDoHE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132025 CHEBI:64249 (3S,6R)-6-hydroxy-3-isopropenylheptanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64249 CHEBI:64248 tunicamycin B1 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64248 CHEBI:132024 19-HETrE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132024 CHEBI:132026 20-HETrE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132026 CHEBI:132028 tauroursodeoxycholate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132028 CHEBI:78882 1-(alk-1-enyl)-2-acylglycero-3-phospho-L-serine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78882 CHEBI:132021 S-(3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl)-4'-phosphopantetheine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132021 CHEBI:132020 S-choloyl-4'-phosphopantetheine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132020 CHEBI:64250 tunicamycin B2 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64250 CHEBI:64254 1,4-dihydroxy-6-naphthoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64254 CHEBI:64253 3-demethylubiquinol-6 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64253 CHEBI:64252 cyclic dehypoxanthinylfutalosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64252 CHEBI:64258 erythromycin C(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64258 CHEBI:64257 tunicamycin C2 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64257 CHEBI:64256 tunicamycin C1 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64256 CHEBI:64255 tunicamycin B3 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64255 CHEBI:64259 (6E)-8-oxolinalool biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64259 CHEBI:78892 fatty acid anion 19:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78892 CHEBI:132030 glycoursodeoxycholate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132030 CHEBI:78896 tetradecenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78896 CHEBI:132031 13-hydroxytetradecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132031 CHEBI:30801 terephthalate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30801 CHEBI:30800 phthalate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30800 GO:0062091 Ycf2/FtsHi complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062091 TIC complex associated chloroplast protein import motor A protein complex located in the chloroplast inner membrane and facing the stroma that is associated with the chloroplast inner membrane translocase complex and provides the ATPase motor activity to drive import of proteins into the chloroplast stroma. GO:0062090 positive regulation of taurine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062090 Any process that activates or increases the frequency, rate or extent of taurine biosynthesis. GO:0062093 lysophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062093 The selective autophagy process in which a damaged lysosome is degraded by macroautophagy. GO:0062092 Yae1-Lto1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062092 A cytosolic complex that functions as an substrate-specific adaptor, linking the cytosolic iron-sulfur protein assembly (CIA) targeting complex to apo-Rli1p, an ABC protein involved in ribosome recycling, facilitating Fe-S cluster insertion and the maturation of the Rli1p. GO:0062095 endoplasmic reticulum-peroxisome tethering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062095 The attachment of an endoplasmic reticulum membrane to a peroxisome via molecular tethers that physically bridge the two membranes and attach them to each other. GO:0062094 stomach development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062094 The process whose specific outcome is the progression of the stomach over time, from its formation to the mature structure. The stomach is an expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ. GO:0062097 chemosynthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062097 Wikipedia:Chemosynthesis The cellular metabolic process in which organic chemical compounds are synthesized from carbon-containing molecules and nutrients using energy obtained from the oxidation of inorganic compounds or methane. GO:0062096 kinetochore disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062096 The disaggregation of a kinetochore into its constituent components. GO:0062099 negative regulation of programmed necrotic cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062099 Any process that decreases the frequency, rate or extent of programmed necrotic cell death. CHEBI:30807 tetradecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30807 GO:0062098 regulation of programmed necrotic cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062098 Any process that modulates the frequency, rate or extent of programmed necrotic cell death. NCBITaxon:27896 Planariidae organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_27896 CHEBI:30805 dodecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30805 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0086059 voltage-gated calcium channel activity involved in sinoatrial node cardiac muscle cell action potential|voltage-gated calcium channel activity involved in sinus node cardiac muscle cell action potential|voltage-gated calcium channel activity involved in SAN cardiac muscle cell action potential|voltage-gated calcium channel activity involved in SA node cardiac muscle cell action potential Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an SA node cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. GO:0086058 voltage-gated calcium channel activity involved in Purkinje myocyte cell action potential biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0086058 Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an Purkinje myocyte cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0086057 voltage-gated calcium channel activity involved in bundle of His cardiac muscle cell action potential Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of a bundle of His cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0086056 voltage-gated calcium channel activity involved in atrioventricular node cardiac muscle cell action potential|voltage-gated calcium channel activity involved in AV node cardiac muscle cell action potential Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an AV node cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. GO:0086055 Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086055 The process that mediates signaling interactions between a Purkinje myocyte and a ventricular cardiac muscle cell by transfer of current between their adjacent cytoplasms via intercellular protein channels. GO:0086054 bundle of His cell to Purkinje myocyte communication by electrical coupling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086054 bundle of His cardiac muscle cell to Purkinje myocyte communication by electrical coupling The process that mediates signaling interactions between a bundle of His cardiac muscle cell and a Purkinje myocyte by transfer of current between their adjacent cytoplasms via intercellular protein channels. GO:0086053 AV node cell to bundle of His cell communication by electrical coupling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086053 atrioventricular node cell to bundle of His cell communication by electrical coupling The process that mediates signaling interactions between an AV node cardiomyocyte and a bundle of His cardiac muscle cell by transfer of current between their adjacent cytoplasms via intercellular protein channels. GO:0086052 membrane repolarization during SA node cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086052 membrane repolarization involved in regulation of SAN cardiac muscle cell action potential|membrane repolarization involved in regulation of sinus node cardiac muscle cell action potential|membrane repolarization involved in regulation of SA node cardiac muscle cell action potential|membrane repolarization involved in regulation of sinoatrial node cardiac muscle cell action potential The process in which an SA node cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential. GO:0086051 membrane repolarization during Purkinje myocyte action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086051 The process in which ions are transported across a membrane such that the Purkinje myocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential. GO:0086050 membrane repolarization during bundle of His cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086050 membrane repolarization during bundle of His cardiac muscle cell action potential The process in which ions are transported across a membrane such that the bundle of His cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential. CHEBI:30814 digallic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30814 CHEBI:30813 decanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30813 GO:0062080 inhibitory MHC class Ib receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062080 Combining with a MHC class Ib protein complex to mediate signaling that inhibits activation of a lymphocyte. GO:0062082 HLA-E specific inhibitory MHC class Ib receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062082 Combining with a MHC class Ib molecule of the HLA-A subclass to mediate signaling that inhibits activation of a lymphocyte. GO:0062081 activating MHC class Ib receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062081 Combining with a MHC class Ib protein complex to mediate signaling that activates a lymphocyte. GO:0062084 regulation of capsule polysaccharide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062084 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi. GO:0062083 HLA-G specific inhibitory MHC class Ib receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062083 Combining with a MHC class Ib molecule of the HLA-G subclass to mediate signaling that inhibits activation of a lymphocyte. GO:0062086 regulation of vein smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062086 Any process that modulates the frequency, rate or extent of vein smooth muscle contraction. GO:0062085 positive regulation of capsule polysaccharide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062085 Any process that activates, maintains or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi. GO:0062088 negative regulation of vein smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062088 Any process that decreases the frequency, rate or extent of vein smooth muscle contraction. GO:0062087 positive regulation of vein smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062087 Any process that increases the frequency, rate or extent of vein smooth muscle contraction. CHEBI:30817 trans-urocanic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30817 GO:0062089 regulation of taurine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062089 Any process that modulates the rate, frequency or extent of taurine biosynthesis. GO:0086049 membrane repolarization during AV node cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086049 membrane repolarization involved in regulation of atrioventricular node cardiac muscle cell action potential|membrane repolarization involved in regulation of AV node cardiac muscle cell action potential The process in which ions are transported across a membrane such that the AV node cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential. CHEBI:30816 vanillic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30816 GO:0086048 membrane depolarization during bundle of His cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086048 membrane depolarization during bundle of His cardiac muscle cell action potential The process in which bundle of His cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential. GO:0086047 membrane depolarization during Purkinje myocyte cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086047 The process in which Purkinje myocyte membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential. GO:0086046 membrane depolarization during SA node cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086046 membrane depolarization involved in regulation of SAN cardiac muscle cell action potential|membrane depolarization involved in regulation of sinus node cardiac muscle cell action potential|membrane depolarization involved in regulation of SA node cardiac muscle cell action potential|membrane depolarization involved in regulation of sinoatrial node cardiac muscle cell action potential The process in which SA node cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential. GO:0086045 membrane depolarization during AV node cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086045 membrane depolarization during AV node cardiac muscle cell action potential|membrane depolarization during atrioventricular node cardiac muscle cell action potential The process in which AV node cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential. CHEBI:8602 pseudobaptigenin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_8602 GO:0086044 atrial cardiac muscle cell to AV node cell communication by electrical coupling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086044 atrial cardiomyocyte to atrioventricular node cell communication by electrical coupling|atrial cardiomyocyte to AV node cell communication by electrical coupling The process that mediates signaling interactions between an atrial cardiomyocyte and an AV node cell by transfer of current between their adjacent cytoplasms via intercellular protein channels. GO:0086043 bundle of His cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086043 bundle of His cardiac muscle cell action potential An action potential that occurs in a bundle of His cell. GO:0086042 cardiac muscle cell-cardiac muscle cell adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086042 cardiomyocyte-cardiomyocyte adhesion The attachment of one cardiomyocyte to another cardiomyocyte via adhesion molecules. GO:0086041 voltage-gated potassium channel activity involved in SA node cell action potential depolarization biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0086041 voltage-gated potassium channel activity involved in SAN cell action potential depolarization|voltage-gated potassium channel activity involved in sinus node cell action potential depolarization|voltage-gated potassium channel activity involved in sinoatrial node cell action potential depolarization Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an SA node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. GO:0086040 sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0086040 sodium:hydrogen antiporter activity involved in regulation of cardiac muscle cell membrane potential Enables the transfer of a solute or solutes from one side of a cardiac muscle cell membrane to the other according to the reaction: Na+(out) + H+(in) = Na+(in) + H+(out). This transfer contributes to the regulation of the cardiac muscle cell plasma membrane potential. GO:0086079 gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0086079 A wide pore channel activity that enables a direct cytoplasmic connection from a Purkinje myocyte to a ventricular cardiac muscle cell. The gap junction passes electrical signals between the cells contributing to cardiac conduction. GO:0086078 gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0086078 A wide pore channel activity that enables a direct cytoplasmic connection from a bundle of His cell to a Purkinje myocyte. The gap junction passes electrical signals between the cells contributing to cardiac conduction. GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0086077 gap junction channel activity involved in atrioventricular node cell-bundle of His cell electrical coupling A wide pore channel activity that enables a direct cytoplasmic connection from an AV node cell to a bundle of His cell. The gap junction passes electrical signals between the cells contributing to cardiac conduction. GO:0086076 gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0086076 gap junction channel activity involved in atrial cardiomyocyte-AV node cell electrical coupling|gap junction channel activity involved in atrial cardiomyocyte-atrioventricular node cell electrical coupling A wide pore channel activity that enables a direct cytoplasmic connection from an atrial cardiomyocyte to an AV node cell. The gap junction passes electrical signals between the cells contributing to cardiac conduction. GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0086075 A wide pore channel activity that enables a direct cytoplasmic connection from one cardiomyocyte to an adjacent cardiomyocyte. The gap junction passes electrical signals between the cells contributing to cardiac conduction. GO:0086074 Purkinje myocyte-ventricular cardiac muscle cell adhesion involved in cell communication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086074 The attachment of an Purkinje myocyte to a ventricular cardiac muscle cell via adhesion molecules that results in the cells being juxtaposed so that they can communicate. GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086073 The attachment of a bundle of His cell to a Purkinje myocyte via adhesion molecules that results in the cells being juxtaposed so that they can communicate. GO:0086072 AV node cell-bundle of His cell adhesion involved in cell communication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086072 atrioventricular node cell-bundle of His cell adhesion involved in cell communication The attachment of an AV node cell to an bundle of His cell via adhesion molecules that results in the cells being juxtaposed so that they can communicate. GO:0086071 atrial cardiac muscle cell-AV node cell adhesion involved in cell communication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086071 atrial cardiomyocyte-atrioventricular node cell adhesion involved in cell communication|atrial cardiomyocyte-AV node cell adhesion involved in cell communication The attachment of an atrial cardiomyocyte to an AV node cell via adhesion molecules that results in the cells being juxtaposed so that they can communicate. GO:0086070 SA node cell to atrial cardiac muscle cell communication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086070 sinoatrial node cardiomyocyte to atrial cardiomyocyte communication|SA node cardiomyocyte to atrial cardiomyocyte communication|sinus node cardiomyocyte to atrial cardiomyocyte communication|SA node cardiac muscle cell to atrial cardiac muscle cell communication|SAN cardiomyocyte to atrial cardiomyocyte communication The process that mediates interactions between an SA node cardiomyocyte and its surroundings that contributes to the process of the SA node cardiomyocyte communicating with an atrial cardiomyocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. CHEBI:29806 fumarate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29806 CHEBI:29805 glycolate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29805 BSPO:0015101 in_dorsal_side_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BSPO_0015101 BSPO:0015101 GO:0086069 bundle of His cell to Purkinje myocyte communication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086069 bundle of His cardiac muscle cell to Purkinje myocyte communication The process that mediates interactions between a bundle of His cell and its surroundings that contributes to the process of the bundle of His cell communicating with a Purkinje myocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. BSPO:0015102 in_ventral_side_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BSPO_0015102 BSPO:0015102 GO:0086068 Purkinje myocyte to ventricular cardiac muscle cell communication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086068 The process that mediates interactions between a Purkinje myocyte and its surroundings that contributes to the process of the Purkinje myocyte communicating with a ventricular cardiac muscle cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. GO:0086067 AV node cell to bundle of His cell communication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086067 atrioventricular node cell to bundle of His cell communication The process that mediates interactions between an AV node cell and its surroundings that contributes to the process of the AV node cell communicating with a bundle of His cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. GO:0086066 atrial cardiac muscle cell to AV node cell communication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086066 atrial cardiomyocyte to atrioventricular node cell communication|atrial cardiomyocyte to AV node cell communication The process that mediates interactions between an atrial cardiomyocyte and its surroundings that contributes to the process of the atrial cardiomyocyte communicating with an AV node cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. GO:0086065 cell communication involved in cardiac conduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086065 Any process that mediates interactions between a cell and its surroundings that contributes to the process of cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. GO:0086064 cell communication by electrical coupling involved in cardiac conduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086064 The process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels and contributes to the process of cardiac conduction. GO:0086063 voltage-gated sodium channel activity involved in SA node cell action potential biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0086063 voltage-gated sodium channel activity involved in sinus node cardiac muscle cell action potential|voltage-gated sodium channel activity involved in SA node cardiac muscle cell action potential|voltage-gated sodium channel activity involved in sinoatrial node cardiac muscle cell action potential|voltage-gated sodium channel activity involved in SAN cardiac muscle cell action potential Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of an SA node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0086062 Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a Purkinje myocyte contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. GO:0086061 voltage-gated sodium channel activity involved in bundle of His cell action potential biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0086061 voltage-gated sodium channel activity involved in bundle of His cardiac muscle cell action potential Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a bundle of His cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. GO:0086060 voltage-gated sodium channel activity involved in AV node cell action potential biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0086060 voltage-gated sodium channel activity involved in atrioventricular node cardiac muscle cell action potential|voltage-gated sodium channel activity involved in AV node cardiac muscle cell action potential Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of an AV node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. CHEBI:29807 glycyrrhizinate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29807 CHEBI:146293 9-HPODE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_146293 CHEBI:146296 N-acetyl-D-leucine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_146296 CHEBI:8638 (9Z,11E,13Z)-octadecatrienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_8638 GO:0086099 phospholipase C-activating angiotensin-activated signaling pathway involved in heart process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086099 phospholipase C-activating angiotensin-mediated signaling pathway involved in heart process|angiotensin receptor signaling pathway via activation of phospholipase C involved in heart process|PLC-activating angiotensin receptor signaling pathway involved in heart process|cardiac angiotensin receptor signaling pathway via activation of PLC|Gq-coupled angiotensin receptor signaling pathway involved in heart process An angiotensin-mediated signaling pathway that contributes to a circulatory system process carried out by the heart, where the activated receptor transmits the signal via Gq-mediated activation of phospholipase C (PLC). PLC hydrolyses phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers inositol-1,4,5,-triphosphate (IP3) and diacylglycerol (DAG). DAG activates protein kinase C (PKC), whilst IP3 binds intracellular receptors to induce the release of Ca2+ from intracellular stores. GO:0086098 angiotensin-activated signaling pathway involved in heart process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086098 angiotensin-mediated signaling pathway involved in heart process|angiotensin receptor signalling pathway involved in heart process|angiotensin receptor signaling pathway involved in heart process An angiotensin receptor signaling pathway which contributes to a circulatory system process carried out by the heart. GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086097 phospholipase C-activating angiotensin receptor signaling pathway|Gq-coupled angiotensin receptor signaling pathway|phospholipase C-activating angiotensin-mediated signaling pathway|angiotensin-mediated signaling pathway via activation of phospholipase C|PLC-activating angiotensin receptor signaling pathway An angiotensin-mediated signaling pathway where the activated receptor transmits the signal via Gq-mediated activation of phospholipase C (PLC). PLC hydrolyses phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers inositol-1,4,5,-triphosphate (IP3) and diacylglycerol (DAG). DAG activates protein kinase C (PKC), whilst IP3 binds intracellular receptors to induce the release of Ca2+ from intracellular stores. GO:0086096 adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086096 cardiac adrenergic receptor signaling pathway via inhibition of adenylate cyclase activity|Gi-coupled Beta2-AR signaling pathway involved in heart process|Gi-coupled adrenergic receptor signaling pathway involved in heart process|G-inhibitory-coupled Beta2AR signaling pathway involved in heart process An adrenergic receptor signaling pathway which contributes to a circulatory system process carried out by the heart, where the activated adrenergic receptor transmits the signal by Gi-mediated inhibition of adenylate cyclase activity. GO:0086095 positive regulation of IKACh channel activity by G protein-coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086095 muscarinic receptor signaling pathway involved in activation of IKACH|Gbeta/gamma-coupled muscarinic receptor signaling pathway involved in negative regulation of heart rate|positive regulation of IKACh channel activity by G-protein coupled acetylcholine receptor signaling|muscarinic receptor signaling pathway involved in ion channel activation|cardiac muscarinic receptor signaling via Gbeta/gamma A G protein-coupled acetylcholine receptor signaling pathway that contributes to a decrease in frequency or rate of heart contraction through activation of the IKACh potassium channel. Binding of acetylcholine to a G protein-coupled acetylcholine receptor (muscarinic receptor) on the surface of the signal-receiving cell results in liberation of the G-beta/gamma complex from the alpha subunit. The G-beta/gamma complex binds directly to the inward-rectifying potassium channel IKACh. Once the ion channel is activated, potassium ions (K+) flow out of the cell and cause it to hyperpolarize. In its hyperpolarized state, action potentials cannot be fired as quickly as possible, which slows the heart rate. CHEBI:8630 pterostilbene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_8630 GO:0086094 positive regulation of ryanodine-sensitive calcium-release channel activity by adrenergic receptor signaling pathway involved in positive regulation of cardiac muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086094 adrenergic receptor signaling pathway involved in positive regulation of cardiac muscle contraction via ryanodine receptor phosphorylation An adrenergic receptor signaling pathway that contributes to an increase in frequency or rate of cardiac muscle contraction through phosphorylation and enhancement of the ryanodine receptor, a calcium-activated calcium-release channel found in the membrane of the sarcoplasmic reticulum. An adrenergic receptor-activated adenylate cyclase generates cAMP. cAMP then activates the cAMP-dependent protein kinase A (PKA), which phosphorylates the ryanodine receptor (RyR). PKA-phosphorylation of RyR enhances channel activity by sensitizing the channel to cytosolic calcium. Cytosolic calcium stimulates contractile proteins to promote muscle contraction. GO:0086093 G protein-coupled acetylcholine receptor signaling pathway involved in heart process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086093 M2 receptor signaling pathway involved in heart process|G-protein coupled acetylcholine receptor signalling pathway involved in heart process|muscarinic receptor signaling pathway involved in heart process|G-protein coupled acetylcholine receptor signaling pathway involved in heart process A G protein-coupled acetylcholine receptor signaling pathway, which contributes to a circulatory system process carried out by the heart. GO:0086092 regulation of the force of heart contraction by cardiac conduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086092 A cardiac conduction process that modulates the extent of heart contraction, changing the force with which blood is propelled. GO:0086091 regulation of heart rate by cardiac conduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086091 A cardiac conduction process that modulates the frequency or rate of heart contraction. GO:0086090 voltage-gated potassium channel activity involved in SA node cell action potential repolarization biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0086090 voltage-gated potassium channel activity involved in sinoatrial node cell action potential|voltage-gated potassium channel activity involved in SAN cell action potential|voltage-gated potassium channel activity involved in sinus node cell action potential Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an SA node cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. CHEBI:146289 9-HPETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_146289 CHEBI:146281 anthracenone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_146281 CHEBI:146288 8-HPETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_146288 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0086089 voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an atrial cardiomyocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. GO:0086088 voltage-gated potassium channel activity involved in Purkinje myocyte action potential repolarization biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0086088 Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a Purkinje myocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. GO:0086087 voltage-gated potassium channel activity involved in bundle of His cell action potential repolarization biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0086087 Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a bundle of His cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. GO:0086086 voltage-gated potassium channel activity involved in AV node cell action potential repolarization biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0086086 voltage-gated potassium channel activity involved in atrioventricular node cardiac muscle cell action potential|voltage-gated potassium channel activity involved in AV node cardiac muscle cell action potential repolarization Catalysis of the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an AV node cardiac muscle cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. CHEBI:146291 11-HPETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_146291 GO:0086085 cell adhesive protein binding involved in SA cardiac muscle cell-atrial cardiac muscle cell communication biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0086085 cell adhesive protein binding involved in SA cardiomyocyte-atrial cardiomyocyte communication Interacting selectively and non-covalently with any protein or protein complex that results in the connection of an SA cardiomyocyte with an atrial cardiomyocyte and contributes to the communication between the two cells. CHEBI:146290 9(S)-HPETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_146290 GO:0086084 cell adhesive protein binding involved in Purkinje myocyte-ventricular cardiac muscle cell communication biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0086084 Interacting selectively and non-covalently with any protein or protein complex that results in the connection of a Purkinje myocyte with an ventricular cardiac muscle cell and contributes to the communication between the two cells. GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0086083 Interacting selectively and non-covalently with any protein or protein complex that results in the connection of a bundle of His cell with a Purkinje myocyte and contributes to the communication between the two cells. GO:0086082 cell adhesive protein binding involved in AV node cell-bundle of His cell communication biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0086082 cell adhesive protein binding involved in atrioventricular node cell-bundle of His cell communication Interacting selectively and non-covalently with any protein or protein complex that results in the connection of an AV node cell with a bundle of His cell and contributes to the communication between the two cells. GO:0086081 cell adhesive protein binding involved in atrial cardiac muscle cell-AV node cell communication biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0086081 cell adhesive protein binding involved in atrial cardiomyocyte-atrioventricular node cell communication|cell adhesive protein binding involved in atrial cardiomyocyte-AV node cell communication Interacting selectively and non-covalently with any protein or protein complex that results in the connection of an atrial cardiomyocyte with an AV node cell and contributes to the communication between the two cells. GO:0086080 protein binding involved in heterotypic cell-cell adhesion biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0086080 Interacting selectively and non-covalently with any protein or protein complex contributing to the adhesion of two different types of cells. CHEBI:78804 Caenorhabditis elegans metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78804 CHEBI:78803 nematode metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78803 CHEBI:78802 diarylheptanoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78802 CHEBI:78808 (9Z)-hexacosenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78808 CHEBI:146270 oneirogen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_146270 CHEBI:78809 N(6)-octanoyl-L-lysine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78809 CHEBI:8614 psilocybin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_8614 CHEBI:8613 psilocin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_8613 CHEBI:78815 N(6)-(S(8)-acetyldihydrolipoyl)-L-lysine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78815 CHEBI:78814 1-oleoyl-2-myristoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78814 CHEBI:78813 1-oleoyl-2-palmitoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78813 CHEBI:78812 ascr#2 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78812 CHEBI:78818 O-(S-3-oxopentanoylpantetheine-4'-phosphoryl)serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78818 CHEBI:78817 (5R)-5-hydroxyhexan-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78817 CHEBI:78816 5-hydroxyhexan-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78816 CHEBI:78811 heptanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78811 CHEBI:78810 1-oleoyl-2-palmitoleoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78810 GO:0052689 carboxylic ester hydrolase activity biolink:MolecularActivity go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0052689 RHEA:21164|Reactome:R-HSA-5693691|Reactome:R-HSA-8937442|EC:3.1.1.1|EC:3.1.1.-|MetaCyc:CARBOXYLESTERASE-RXN|Reactome:R-HSA-9619024|UM-BBD_reactionID:r1025|KEGG_REACTION:R00630 carboxyl ester hydrolase activity|carboxylic acid esterase activity|carboxylesterase activity|vitamin A esterase|carboxylate esterase activity|carboxylic esterase activity|carboxylic ester hydrolase activity|cocaine esterase activity|procaine esterase activity|carboxyesterase activity|esterase B|esterase A|ali-esterase activity|triacetin esterase|serine esterase activity|B-esterase activity|nonspecific carboxylesterase activity|alpha-carboxylesterase activity Catalysis of the hydrolysis of a carboxylic ester bond. GO:0003711 transcription elongation regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003711 transcriptional elongation regulator activity|transcription elongation regulator activity|transcription elongation factor activity A molecular function that regulates transcriptional elongation by enabling the transition from transcription initiation to elongation or by altering the elongation properties of the enzyme during the elongation phase of transcription. CHEBI:88190 2-oxido-5-methylquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88190 GO:0052688 (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052688 KEGG_REACTION:R06515 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity Catalysis of the reaction: (3R)-3-isopropenyl-6-oxoheptanoate + CoA-SH + ATP = H2O + AMP + diphosphate + (3R)-3-isopropenyl-6-oxoheptanoyl-CoA. GO:0003710 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003710 GO:0003713 transcription coactivator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003713 transcription coactivator activity|RNA polymerase II transcription coactivator activity|transcription co-activator activity|RNA polymerase II transcription mediator activity|RNA polymerase II transcription co-activator activity A transcription coregulator activity that activates or increases the transcription of specific gene sets via binding to a DNA-bound DNA-binding transcription factor, either on its own or as part of a complex. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coactivators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators. A fourth class of coactivator activity is the bridging of a DNA-binding transcription factor to the general (basal) transcription machinery. The Mediator complex, which bridges sequence-specific DNA binding transcription factors and RNA polymerase, is also a transcription coactivator. GO:0052687 (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052687 KEGG_REACTION:R06396 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity Catalysis of the reaction: (3R)-3-isopropenyl-6-oxoheptanoate + CoA-SH + ATP = H2O + ADP + phosphate + (3R)-3-isopropenyl-6-oxoheptanoyl-CoA. GO:0003712 transcription coregulator activity biolink:MolecularActivity go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0003712 RNA polymerase II transcriptional cofactor activity|transcription cofactor activity|transcriptional co-regulator A transcription regulator activity that modulates the transcription of specific gene sets via binding to a DNA-bound DNA-binding transcription factor, either on its own or as part of a complex. Coregulators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators. GO:0052686 perillic acid-CoA ligase (AMP-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052686 KEGG_REACTION:R06368 perillyl-CoA synthetase activity|perillic acid:CoA ligase (AMP-forming) activity Catalysis of the reaction: perillic acid + CoA-SH + ATP = H2O + AMP + diphosphate + perillyl-CoA. CHEBI:30889 L-threo-isocitric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30889 CHEBI:30887 isocitric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30887 CHEBI:30885 lupinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30885 GO:1904439 negative regulation of iron ion import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904439 downregulation of ferrous ion import into cell|inhibition of ferrous ion import into cell|down-regulation of ferrous iron import across plasma membrane|down regulation of ferrous ion import into cell|negative regulation of ferrous iron import into cell|downregulation of ferrous iron import across plasma membrane|inhibition of ferrous iron import across plasma membrane|down regulation of ferrous iron import across plasma membrane|negative regulation of ferrous iron import across plasma membrane|negative regulation of ferrous ion import into cell|down-regulation of ferrous ion import into cell Any process that stops, prevents or reduces the frequency, rate or extent of iron ions import across plasma membrane. GO:1904438 regulation of iron ion import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904438 regulation of ferrous ion import into cell|regulation of ferrous iron import into cell|regulation of ferrous iron import across plasma membrane Any process that modulates the frequency, rate or extent of iron ions import across plasma membrane. CL:1000979 ureter smooth muscle cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_1000979 GO:1904437 positive regulation of transferrin receptor binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904437 up-regulation of transferrin receptor binding|activation of transferrin receptor binding|up regulation of transferrin receptor binding|upregulation of transferrin receptor binding Any process that activates or increases the frequency, rate or extent of transferrin receptor binding. GO:1904436 negative regulation of transferrin receptor binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904436 down-regulation of transferrin receptor binding|downregulation of transferrin receptor binding|down regulation of transferrin receptor binding|inhibition of transferrin receptor binding Any process that stops, prevents or reduces the frequency, rate or extent of transferrin receptor binding. GO:1904435 regulation of transferrin receptor binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904435 Any process that modulates the frequency, rate or extent of transferrin receptor binding. GO:0062011 mitochondrial respiratory chain complex IV pre-assembly complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062011 COX pre-assemply complex|COX1 preassemply complex A protein complex that contributes to and regulates mitochondrial respiratory chain complex IV (COX) formation. It acts by regulating mitochondrial COX1 translation and by promoting the assembly of COX components. GO:1904434 positive regulation of ferrous iron binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904434 up regulation of ferrous iron binding|upregulation of ferrous iron binding|activation of ferrous iron binding|up-regulation of ferrous iron binding Any process that activates or increases the frequency, rate or extent of ferrous iron binding. GO:0062010 primitive palate development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062010 The biological process whose specific outcome is the progression of the primitive palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. GO:1904433 negative regulation of ferrous iron binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904433 down-regulation of ferrous iron binding|downregulation of ferrous iron binding|down regulation of ferrous iron binding|inhibition of ferrous iron binding Any process that stops, prevents or reduces the frequency, rate or extent of ferrous iron binding. GO:0062013 positive regulation of small molecule metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062013 positive regulation of small molecule metabolism Any process that activates or increases the frequency, rate or extent of a small molecule metabolic process. GO:1904432 regulation of ferrous iron binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904432 Any process that modulates the frequency, rate or extent of ferrous iron binding. GO:0062012 regulation of small molecule metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062012 regulation of small molecule metabolism Any process that modulates the rate, frequency or extent of a small molecule metabolic process. GO:1904442 negative regulation of thyroid gland epithelial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904442 inhibition of Hurthle cell proliferation|negative regulation of thyroid follicular cell proliferation|down-regulation of thyroid follicular cell proliferation|down-regulation of thyroid gland epithelial cell proliferation|negative regulation of Hurthle cell proliferation|down-regulation of Hurthle cell proliferation|inhibition of thyroid gland epithelial cell proliferation|inhibition of thyroid follicular cell proliferation|downregulation of Hurthle cell proliferation|down regulation of thyroid follicular cell proliferation|down regulation of Hurthle cell proliferation|down regulation of thyroid gland epithelial cell proliferation|downregulation of thyroid follicular cell proliferation|downregulation of thyroid gland epithelial cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of thyroid gland epithelial cell proliferation. GO:1904441 regulation of thyroid gland epithelial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904441 regulation of Hurthle cell proliferation|regulation of thyroid follicular cell proliferation Any process that modulates the frequency, rate or extent of thyroid gland epithelial cell proliferation. GO:0062014 negative regulation of small molecule metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062014 negative regulation of small molecule metabolism Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process. GO:1904440 positive regulation of iron ion import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904440 positive regulation of ferrous iron import across plasma membrane|activation of ferrous iron import across plasma membrane|positive regulation of ferrous ion import into cell|up-regulation of ferrous iron import across plasma membrane|up regulation of ferrous ion import into cell|positive regulation of ferrous iron import into cell|upregulation of ferrous ion import into cell|up regulation of ferrous iron import across plasma membrane|activation of ferrous ion import into cell|up-regulation of ferrous ion import into cell|upregulation of ferrous iron import across plasma membrane Any process that activates or increases the frequency, rate or extent of iron ions import across plasma membrane. CHEBI:39215 antibiotic pesticide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39215 GO:0052681 alpha-bisabolene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052681 KEGG_REACTION:R08370|EC:4.2.3.38|MetaCyc:RXN-8550|RHEA:25436 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [(E)-alpha-bisabolene-forming] activity|bisabolene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (E,R)-alpha-bisabolene + diphosphate. GO:0003719 obsolete transcription factor binding, cytoplasmic sequestering biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003719 transcription factor binding, cytoplasmic sequestering OBSOLETE. (Was not defined before being made obsolete). CHEBI:15243 threonate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15243 GO:0052680 epi-isozizaene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052680 MetaCyc:RXN-9349|EC:4.2.3.37|KEGG_REACTION:R07830|RHEA:25992 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [(+)-epi-isozizaene-forming] activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (+)-epi-isozizaene + diphosphate. GO:0003718 obsolete RNA polymerase III transcription termination factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003718 Pol III transcription termination factor activity|RNA polymerase III transcription termination factor activity OBSOLETE. Any activity that brings about termination of transcription by RNA polymerase III. CHEBI:30882 2-oxoglutaramic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30882 CHEBI:15245 thymidine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15245 CHEBI:30881 xanthine-8-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30881 GO:0052685 perillic acid-CoA ligase (ADP-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052685 EC:6.2.1.-|KEGG_REACTION:R06367 perillic acid:CoA ligase (ADP-forming) activity|perillyl-CoA synthetase activity Catalysis of the reaction: perillic acid + CoA-SH + ATP = H2O + ADP + phosphate + perillyl-CoA. GO:0003715 obsolete transcription termination factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003715 transcription termination factor activity|transcriptional termination factor activity OBSOLETE. Any activity that brings about termination of transcription. GO:0003714 transcription corepressor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003714 transcription corepressor activity|RNA polymerase II transcription corepressor activity|transcription co-repressor activity|RNA polymerase II transcription co-repressor activity A transcription coregulator activity that represses or decreases the transcription of specific gene sets via binding to a DNA-bound DNA-binding transcription factor, either on its own or as part of a complex. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription corepressors modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators. GO:0052684 L-serine hydro-lyase (adding indole, L-tryptophan-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052684 EC:4.2.1.122|MetaCyc:RXN0-2382|KEGG_REACTION:R00674|RHEA:26434 tryptophan synthase beta subunit activity|L-serine hydro-lyase (adding indole; L-tryptophan-forming) activity Catalysis of the reaction: indole + L-serine = L-tryptophan + H2O. GO:0052683 (Z)-gamma-bisabolene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052683 MetaCyc:RXN-10005|RHEA:26081|EC:4.2.3.40 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [(Z)-gamma-bisabolene-forming] activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (Z)-gamma-bisabolene + diphosphate. GO:0003717 obsolete RNA polymerase II transcription termination factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003717 RNA polymerase II transcription termination factor activity|Pol II transcription termination factor activity OBSOLETE. Any activity that brings about termination of transcription by RNA polymerase II. GO:0052682 epi-cedrol synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052682 MetaCyc:RXN-10004|KEGG_REACTION:R09140|EC:4.2.3.39|RHEA:26115 epicedrol synthase activity|(2E,6E)-farnesyl-diphosphate diphosphate-lyase (8-epi-cedrol-forming) activity|8-epicedrol synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + H2O = epi-cedrol + diphosphate. GO:0003716 obsolete RNA polymerase I transcription termination factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003716 Pol I transcription termination factor activity|RNA polymerase I transcription termination factor activity OBSOLETE. Any activity that brings about termination of transcription by RNA polymerase I. GO:0003721 telomerase RNA reverse transcriptase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003721 telomerase, catalyst Catalysis of the extension of the 3' end of a DNA strand by one deoxynucleotide at a time. Cannot initiate a chain de novo; uses the RNA subunit of the telomerase enzyme complex as its template. GO:0052699 ergothioneine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052699 2-mercaptoergothioneine trimethylbetaine anabolism|2-mercaptoergothioneine trimethylbetaine biosynthesis|ergothioneine biosynthesis|ergothioneine anabolism|2-mercaptoergothioneine trimethylbetaine synthesis|ergothioneine synthesis|2-mercaptoergothioneine trimethylbetaine formation|ergothioneine formation|2-mercaptoergothioneine trimethylbetaine biosynthetic process|(2S)-3-(2-mercapto-1H-imidazol-5-yl)-2-(trimethylazaniumyl)propanoate biosynthetic process The chemical reactions and pathways resulting in the formation of ergothioneine, a naturally occurring metabolite of histidine with antioxidant properties. GO:0052698 ergothioneine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052698 2-mercaptoergothioneine trimethylbetaine metabolic process|(2S)-3-(2-mercapto-1H-imidazol-5-yl)-2-(trimethylazaniumyl)propanoate metabolic process|ergothioneine metabolism|2-mercaptoergothioneine trimethylbetaine metabolism The chemical reactions and pathways involving ergothioneine, a naturally occurring metabolite of histidine with antioxidant properties. GO:0003724 RNA helicase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003724 Reactome:R-HSA-72647|EC:3.6.4.13 ATP-dependent RNA helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix. GO:0003723 RNA binding biolink:MolecularActivity go-plus goslim_plant|goslim_drosophila|goslim_aspergillus|goslim_generic|goslim_flybase_ribbon|goslim_chembl|goslim_mouse|goslim_yeast|goslim_candida|goslim_agr http://purl.obolibrary.org/obo/GO_0003723 Reactome:R-HSA-203922 poly-A RNA binding|poly(A)-RNA binding|base pairing with RNA|poly(A) RNA binding Interacting selectively and non-covalently with an RNA molecule or a portion thereof. GO:0052697 xenobiotic glucuronidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052697 phase II metabolism The modification of a xenobiotic substance by the conjugation of glucuronic acid. The resultant glucuronosides are often much more water-soluble than the xenobiotic precursor, enabling efficient excretion. CHEBI:88184 metal allergen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88184 GO:0003720 telomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003720 Reactome:R-HSA-164617|Reactome:R-HSA-163090 Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes extension of the 3'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence. CHEBI:30897 L-erythro-isocitrate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30897 CHEBI:30896 L-threo-isocitrate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30896 CHEBI:88188 drug allergen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88188 GO:1904449 negative regulation of aspartate secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904449 down-regulation of aspartate secretion|inhibition of aspartate secretion|down regulation of aspartate secretion|downregulation of aspartate secretion Any process that stops, prevents or reduces the frequency, rate or extent of aspartate secretion. CHEBI:88187 penicillin allergen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88187 GO:1904448 regulation of aspartate secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904448 Any process that modulates the frequency, rate or extent of aspartate secretion. GO:1904447 folate import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904447 folate import into cell|folic acid import across plasma membrane The directed movement of folic acid from outside of a cell, across the plasma membrane and into the cytosol. GO:1904446 positive regulation of establishment of Sertoli cell barrier biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904446 up regulation of establishment of blood-testis barrier|activation of establishment of blood-testis barrier|positive regulation of establishment of SCB|positive regulation of establishment of blood-testis barrier|up regulation of establishment of SCB|positive regulation of establishment of BTB|up regulation of establishment of Sertoli cell barrier|up regulation of establishment of BTB|activation of establishment of Sertoli cell barrier|up-regulation of establishment of blood-testis barrier|upregulation of establishment of SCB|upregulation of establishment of BTB|up-regulation of establishment of Sertoli cell barrier|upregulation of establishment of blood-testis barrier|activation of establishment of SCB|up-regulation of establishment of SCB|up-regulation of establishment of BTB|activation of establishment of BTB|upregulation of establishment of Sertoli cell barrier Any process that activates or increases the frequency, rate or extent of establishment of Sertoli cell barrier. GO:0062000 positive regulation of cardiac endothelial to mesenchymal transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062000 Any process that activates or increases the frequency, rate or extent of cardiac endothelial to mesenchymal trnasition. GO:1904445 negative regulation of establishment of Sertoli cell barrier biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904445 downregulation of establishment of Sertoli cell barrier|negative regulation of establishment of blood-testis barrier|down-regulation of establishment of blood-testis barrier|downregulation of establishment of SCB|downregulation of establishment of BTB|down regulation of establishment of SCB|down-regulation of establishment of Sertoli cell barrier|inhibition of establishment of blood-testis barrier|inhibition of establishment of SCB|down regulation of establishment of BTB|inhibition of establishment of BTB|inhibition of establishment of Sertoli cell barrier|down regulation of establishment of blood-testis barrier|downregulation of establishment of blood-testis barrier|down-regulation of establishment of SCB|down regulation of establishment of Sertoli cell barrier|negative regulation of establishment of SCB|negative regulation of establishment of BTB|down-regulation of establishment of BTB Any process that stops, prevents or reduces the frequency, rate or extent of establishment of Sertoli cell barrier. GO:1904444 regulation of establishment of Sertoli cell barrier biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904444 regulation of establishment of SCB|regulation of establishment of BTB|regulation of establishment of blood-testis barrier Any process that modulates the frequency, rate or extent of establishment of Sertoli cell barrier. GO:0062002 regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062002 Any process that modulates the frequency or rate of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity. GO:1904443 positive regulation of thyroid gland epithelial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904443 positive regulation of thyroid follicular cell proliferation|up regulation of thyroid gland epithelial cell proliferation|activation of thyroid gland epithelial cell proliferation|activation of thyroid follicular cell proliferation|up-regulation of Hurthle cell proliferation|activation of Hurthle cell proliferation|up-regulation of thyroid follicular cell proliferation|up-regulation of thyroid gland epithelial cell proliferation|positive regulation of Hurthle cell proliferation|up regulation of Hurthle cell proliferation|upregulation of thyroid follicular cell proliferation|upregulation of thyroid gland epithelial cell proliferation|upregulation of Hurthle cell proliferation|up regulation of thyroid follicular cell proliferation Any process that activates or increases the frequency, rate or extent of thyroid gland epithelial cell proliferation. GO:0062001 negative regulation of cardiac endothelial to mesenchymal transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062001 Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac endothelial to mesenchymal transition. GO:1904453 positive regulation of potassium:proton exchanging ATPase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904453 up-regulation of hydrogen:potassium exchanging ATPase activity|activation of H,K-ATPase activity|positive regulation of H,K-ATPase activity|positive regulation of gastric H+/K+ ATPase|upregulation of (K+ + H+)-ATPase activity|up-regulation of gastric H(+)/K(+) ATPase activity|up regulation of gastric H+/K+ ATPase|positive regulation of H+/K+-exchanging ATPase activity|positive regulation of H(+)/K(+)-exchanging ATPase activity|up-regulation of H+/K+-ATPase activity|up regulation of hydrogen:potassium-exchanging ATPase activity|upregulation of ATP phosphohydrolase (H+/K+-exchanging)|up-regulation of H(+)/K(+)-ATPase activity|up regulation of H(+)/K(+)-exchanging ATPase activity|up regulation of H+/K+-exchanging ATPase activity|upregulation of hydrogen/potassium-exchanging ATPase activity|up-regulation of H+-K+-ATPase activity|activation of hydrogen:potassium-exchanging ATPase activity|upregulation of hydrogen:potassium exchanging ATPase activity|up-regulation of H,K-ATPase activity|upregulation of gastric H(+)/K(+) ATPase activity|up regulation of (K+ + H+)-ATPase activity|upregulation of gastric H+/K+ ATPase|activation of (K+ + H+)-ATPase activity|positive regulation of (K+ + H+)-ATPase activity|upregulation of H(+)/K(+)-ATPase activity|upregulation of H+/K+-ATPase activity|up regulation of ATP phosphohydrolase (H+/K+-exchanging)|upregulation of H(+)/K(+)-exchanging ATPase activity|upregulation of H+-K+-ATPase activity|upregulation of H+/K+-exchanging ATPase activity|up regulation of hydrogen/potassium-exchanging ATPase activity|positive regulation of ATP phosphohydrolase (H+/K+-exchanging)|activation of ATP phosphohydrolase (H+/K+-exchanging)|up regulation of hydrogen:potassium exchanging ATPase activity|positive regulation of hydrogen/potassium-exchanging ATPase activity|activation of hydrogen/potassium-exchanging ATPase activity|up-regulation of hydrogen:potassium-exchanging ATPase activity|upregulation of H,K-ATPase activity|positive regulation of hydrogen:potassium exchanging ATPase activity|activation of hydrogen:potassium exchanging ATPase activity|up regulation of gastric H(+)/K(+) ATPase activity|up-regulation of gastric H+/K+ ATPase|positive regulation of gastric H(+)/K(+) ATPase activity|up-regulation of (K+ + H+)-ATPase activity|positive regulation of hydrogen:potassium-exchanging ATPase activity|up regulation of H+/K+-ATPase activity|up regulation of H(+)/K(+)-ATPase activity|up-regulation of H(+)/K(+)-exchanging ATPase activity|up-regulation of H+/K+-exchanging ATPase activity|positive regulation of H+/K+-ATPase activity|activation of H+/K+-exchanging ATPase activity|activation of H(+)/K(+)-ATPase activity|positive regulation of H(+)/K(+)-ATPase activity|up regulation of H+-K+-ATPase activity|activation of H(+)/K(+)-exchanging ATPase activity|activation of H+/K+-ATPase activity|upregulation of hydrogen:potassium-exchanging ATPase activity|activation of gastric H+/K+ ATPase|positive regulation of H+-K+-ATPase activity|activation of H+-K+-ATPase activity|activation of gastric H(+)/K(+) ATPase activity|up-regulation of ATP phosphohydrolase (H+/K+-exchanging)|up regulation of H,K-ATPase activity|up-regulation of hydrogen/potassium-exchanging ATPase activity Any process that activates or increases the frequency, rate or extent of hydrogen:potassium-exchanging ATPase activity. GO:1904452 negative regulation of potassium:proton exchanging ATPase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904452 negative regulation of H+/K+-ATPase activity|down-regulation of H(+)/K(+)-ATPase activity|down-regulation of H+/K+-ATPase activity|down regulation of hydrogen:potassium-exchanging ATPase activity|negative regulation of H(+)/K(+)-ATPase activity|inhibition of hydrogen:potassium exchanging ATPase activity|negative regulation of H(+)/K(+)-exchanging ATPase activity|down-regulation of H+-K+-ATPase activity|down-regulation of H(+)/K(+)-exchanging ATPase activity|negative regulation of H+-K+-ATPase activity|down-regulation of H+/K+-exchanging ATPase activity|negative regulation of H+/K+-exchanging ATPase activity|downregulation of hydrogen:potassium-exchanging ATPase activity|negative regulation of H,K-ATPase activity|down-regulation of H,K-ATPase activity|down regulation of (K+ + H+)-ATPase activity|inhibition of H(+)/K(+)-ATPase activity|downregulation of gastric H+/K+ ATPase|inhibition of H+/K+-ATPase activity|inhibition of H+-K+-ATPase activity|inhibition of gastric H(+)/K(+) ATPase activity|down regulation of ATP phosphohydrolase (H+/K+-exchanging)|downregulation of (K+ + H+)-ATPase activity|downregulation of H(+)/K(+)-exchanging ATPase activity|downregulation of H+/K+-exchanging ATPase activity|down regulation of gastric H+/K+ ATPase|down regulation of hydrogen/potassium-exchanging ATPase activity|inhibition of H,K-ATPase activity|down regulation of hydrogen:potassium exchanging ATPase activity|down-regulation of hydrogen:potassium-exchanging ATPase activity|downregulation of ATP phosphohydrolase (H+/K+-exchanging)|down regulation of H+/K+-exchanging ATPase activity|down regulation of H(+)/K(+)-exchanging ATPase activity|downregulation of hydrogen/potassium-exchanging ATPase activity|down regulation of gastric H(+)/K(+) ATPase activity|inhibition of H+/K+-exchanging ATPase activity|downregulation of hydrogen:potassium exchanging ATPase activity|inhibition of H(+)/K(+)-exchanging ATPase activity|inhibition of gastric H+/K+ ATPase|down regulation of H(+)/K(+)-ATPase activity|negative regulation of (K+ + H+)-ATPase activity|down regulation of H+/K+-ATPase activity|down-regulation of (K+ + H+)-ATPase activity|downregulation of gastric H(+)/K(+) ATPase activity|inhibition of hydrogen:potassium-exchanging ATPase activity|down regulation of H+-K+-ATPase activity|downregulation of H+/K+-ATPase activity|downregulation of H(+)/K(+)-ATPase activity|negative regulation of ATP phosphohydrolase (H+/K+-exchanging)|down-regulation of ATP phosphohydrolase (H+/K+-exchanging)|down regulation of H,K-ATPase activity|down-regulation of hydrogen/potassium-exchanging ATPase activity|negative regulation of hydrogen/potassium-exchanging ATPase activity|downregulation of H+-K+-ATPase activity|down-regulation of hydrogen:potassium exchanging ATPase activity|negative regulation of hydrogen:potassium exchanging ATPase activity|inhibition of (K+ + H+)-ATPase activity|downregulation of H,K-ATPase activity|down-regulation of gastric H(+)/K(+) ATPase activity|negative regulation of gastric H(+)/K(+) ATPase activity|inhibition of ATP phosphohydrolase (H+/K+-exchanging)|negative regulation of hydrogen:potassium-exchanging ATPase activity|negative regulation of gastric H+/K+ ATPase|down-regulation of gastric H+/K+ ATPase|inhibition of hydrogen/potassium-exchanging ATPase activity Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen:potassium-exchanging ATPase activity. GO:0062003 negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062003 Any process that decreases the frequency or rate of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity. GO:1904451 regulation of potassium:proton exchanging ATPase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904451 regulation of proton pump activity|regulation of (K+ + H+)-ATPase activity|regulation of gastric H+/K+ ATPase|regulation of ATP phosphohydrolase (H+/K+-exchanging)|regulation of hydrogen/potassium-exchanging ATPase activity|regulation of H+/K+-exchanging ATPase activity|regulation of H(+)/K(+)-exchanging ATPase activity|regulation of hydrogen:potassium exchanging ATPase activity|regulation of gastric H(+)/K(+) ATPase activity|regulation of hydrogen:potassium-exchanging ATPase activity|regulation of H(+)/K(+)-ATPase activity|regulation of H+/K+-ATPase activity|regulation of H+-K+-ATPase activity|regulation of H,K-ATPase activity Any process that modulates the frequency, rate or extent of hydrogen:potassium-exchanging ATPase activity. GO:1904450 positive regulation of aspartate secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904450 upregulation of aspartate secretion|up regulation of aspartate secretion|activation of aspartate secretion|up-regulation of aspartate secretion Any process that activates or increases the frequency, rate or extent of aspartate secretion. CHEBI:39226 chlorocarbon biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39226 GO:0062009 secondary palate development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062009 The biological process whose specific outcome is the progression of the secondary palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The secondary palate is the part of the palate formed from the fusion of the two palatine shelves, extensions of the maxillary prominences. CHEBI:15237 thiomorpholine-3-carboxylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15237 GO:0052692 raffinose alpha-galactosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052692 EC:3.2.1.22|KEGG_REACTION:R01103|MetaCyc:RXN-11502 alkaline alpha-galactosidase activity|raffinose galactohydrolase activity|raffinose-specific alkaline alpha-galactosidase activity Catalysis of the reaction: raffinose + H2O = alpha-D-galactose + sucrose. GO:0003729 mRNA binding biolink:MolecularActivity go-plus goslim_generic|goslim_chembl|goslim_yeast http://purl.obolibrary.org/obo/GO_0003729 base pairing with mRNA Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns. GO:0052691 UDP-arabinopyranose mutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052691 RHEA:28350|EC:5.4.99.30|MetaCyc:RXN-11552 UDP-L-arabinopyranose furanomutase activity|uridine-diphosphate-L-arabinose mutase activity|UDP-L-Ara mutase activity|UDP-arabinopyranose pyranomutase activity|UDP-L-arabinose mutase activity Catalysis of the reaction: UDP-beta-L-arabinofuranose = UDP-beta-L-arabinopyranose. GO:0052690 trichloro-p-hydroquinone reductive dehalogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052690 UM-BBD_reactionID:r0315|RHEA:56832 tetrachlorohydroquinone reductive dehalogenase activity|trichlorohydroquinone reductive dehalogenase activity|xenobiotic reductase activity|pentaerythritol tetranitrate reductase activity Catalysis of the reaction: 2,3,6-trichlorohydroquinone + 2 glutathione = 2,6-dichlorohydroquinone + glutathione disulfide + HCl. GO:0003726 double-stranded RNA adenosine deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003726 Reactome:R-HSA-77615|Reactome:R-HSA-77614 double-stranded RNA specific editase activity Catalysis of the reaction: adenosine + H2O = inosine + NH3, in a double-stranded RNA molecule. GO:0052696 flavonoid glucuronidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052696 flavonoid glucuronoside biosynthesis|flavonoid glucuronoside biosynthetic process|flavonoid glucuronide biosynthesis|flavonoid glucuronide biosynthetic process The modification of a flavonoid by the conjugation of glucuronic acid. The resultant flavonoid glucuronosides are often much more water-soluble than the precursor. GO:0003725 double-stranded RNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003725 dsRNA binding Interacting selectively and non-covalently with double-stranded RNA. GO:0052695 cellular glucuronidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052695 cellular glucuronoside biosynthesis|cellular glucuronoside biosynthetic process|cellular glucuronide biosynthetic process|cellular glucuronide biosynthesis The modification of an organic chemical by the conjugation of glucuronic acid. The substances resulting from glucuronidation are known as glucuronosides (or glucuronides) and are often much more water-soluble than the non-glucuronic acid-containing precursor. GO:0003728 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003728 GO:0052694 jasmonoyl-isoleucine-12-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052694 MetaCyc:RXN-12421|RHEA:54808 Catalysis of the reaction: jasmonoyl-isoleucine + NADPH + H+ + O2 = 12-hydroxy-jasmonoyl-isoleucine + NADP+ + H2O. GO:0052693 epoxyqueuosine reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052693 RHEA:32159|EC:1.17.99.6 Catalysis of the reaction: epoxyqueuosine in tRNA + reductant = queuosine in tRNA + oxidised reductant. GO:0003727 single-stranded RNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003727 ssRNA binding Interacting selectively and non-covalently with single-stranded RNA. CHEBI:30867 dihydroorotate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30867 CHEBI:30866 (R)-dihydroorotic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30866 CHEBI:30865 dihydroorotic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30865 CHEBI:30864 (S)-dihydroorotate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30864 GO:0062031 filamentous growth MAPK cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062031 The MAPK cascade which is activated as a result of partial nutrient deprivation and which results in filamentous growth. GO:1904459 negative regulation of substance P secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904459 down-regulation of substance P secretion|inhibition of substance P secretion|down regulation of substance P secretion|downregulation of substance P secretion Any process that stops, prevents or reduces the frequency, rate or extent of substance P secretion. GO:0062030 negative regulation of stress granule assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062030 Any process that stops or decreases the rate, frequency or extent of stress-granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule. GO:1904458 regulation of substance P secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904458 Any process that modulates the frequency, rate or extent of substance P secretion. GO:1904457 positive regulation of neuronal action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904457 activation of neuronal action potential|up-regulation of generation of action potential|up-regulation of neuronal action potential|activation of generation of action potential|positive regulation of generation of action potential|up regulation of generation of action potential|upregulation of neuronal action potential|upregulation of generation of action potential|up regulation of neuronal action potential Any process that activates or increases the frequency, rate or extent of neuronal action potential. GO:0062033 positive regulation of mitotic sister chromatid segregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062033 Any process that starts or increases the frequency, rate or extent of sister chromatid segregation during mitosis. GO:0062032 cichorine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062032 cichorine formation|cichorine biosynthesis|cichorine anabolism|cichorine synthesis The chemical reactions and pathways resulting in the formation of cichorine, a secondary metabolite found in some species of fungi. GO:1904456 negative regulation of neuronal action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904456 inhibition of generation of action potential|down-regulation of neuronal action potential|inhibition of neuronal action potential|down-regulation of generation of action potential|negative regulation of generation of action potential|downregulation of generation of action potential|down regulation of neuronal action potential|down regulation of generation of action potential|downregulation of neuronal action potential Any process that stops, prevents or reduces the frequency, rate or extent of neuronal action potential. GO:0062035 sensory perception of cold stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062035 The series of events required for an organism to receive a cold temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. GO:1904455 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1904455 GO:1904454 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1904454 GO:0062034 L-pipecolic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062034 L-pipecolate biosynthetic process The chemical reactions and pathways resulting in the formation of L-pipecolic acid, a metabolite of lysine. GO:0062037 D-loop DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062037 DNA displacement loop binding Interacting selectively and non-covalently with a DNA D-loop. A D-loop is a three-stranded DNA structure formed by the invasion of a single DNA strand that base pairs with one strand of duplex DNA, while the rest of the double-stranded DNA does not unwind. GO:1904464 regulation of matrix metallopeptidase secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904464 regulation of MMP secretion|regulation of matrix metalloproteinase secretion Any process that modulates the frequency, rate or extent of matrix metallopeptidase secretion. GO:1904463 ergosteryl 3-beta-D-glucoside biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904463 ergosteryl 3-beta-D-glucoside synthesis|ergosteryl 3-beta-D-glucoside formation|ergosteryl 3-beta-D-glucoside biosynthesis|ergosteryl 3-beta-D-glucoside anabolism The chemical reactions and pathways resulting in the formation of ergosteryl 3-beta-D-glucoside. GO:0062036 sensory perception of hot stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062036 The series of events required for an organism to receive a hot temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. GO:1904462 ergosteryl 3-beta-D-glucoside catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904462 ergosteryl 3-beta-D-glucoside catabolism|ergosteryl 3-beta-D-glucoside degradation|ergosteryl 3-beta-D-glucoside breakdown The chemical reactions and pathways resulting in the breakdown of ergosteryl 3-beta-D-glucoside. GO:0062039 biofilm matrix biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062039 A structure lying external to microbial cells. A biofilm is an aggregate of surface-associated cells, and the biofilm matrix is the envelope of polymeric substances that surrounds the cells. GO:0062038 positive regulation of pheromone response MAPK cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062038 Any process that activates or increases the frequency, rate or extent of a pheromone response MAPK cascade. GO:1904461 ergosteryl 3-beta-D-glucoside metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904461 ergosteryl 3-beta-D-glucoside metabolism The chemical reactions and pathways involving ergosteryl 3-beta-D-glucoside. GO:1904460 positive regulation of substance P secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904460 up regulation of substance P secretion|activation of substance P secretion|up-regulation of substance P secretion|upregulation of substance P secretion Any process that activates or increases the frequency, rate or extent of substance P secretion. CHEBI:30861 methylmalonate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30861 CHEBI:30860 methylmalonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30860 CHEBI:15266 triphosphate ion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15266 CHEBI:8653 pyocyanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_8653 GO:0003700 DNA-binding transcription factor activity biolink:MolecularActivity go-plus goslim_plant|goslim_drosophila|goslim_aspergillus|goslim_metagenomics|goslim_generic|goslim_chembl|goslim_mouse|goslim_agr|goslim_yeast|goslim_candida http://purl.obolibrary.org/obo/GO_0003700 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding|transcription factor activity|transcription factor activity, metal ion regulated sequence-specific DNA binding|bacterial-type DNA binding transcription factor activity|transcription factor activity, bacterial-type RNA polymerase proximal promoter sequence-specific DNA binding|sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity|transcription factor activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding|metal ion regulated sequence-specific DNA binding transcription factor activity|gene-specific transcription factor activity|nucleic acid binding transcription factor activity|bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding|bacterial-type RNA polymerase transcription enhancer sequence-specific DNA binding transcription factor activity|transcription factor activity, bacterial-type RNA polymerase transcription enhancer sequence-specific binding|bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity|DNA binding transcription factor activity|metal ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity|sequence-specific DNA binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. GO:0003702 obsolete RNA polymerase II transcription factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003702 RNA polymerase II transcription factor activity OBSOLETE. Functions to initiate or regulate RNA polymerase II transcription. CHEBI:30879 alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30879 GO:0003701 obsolete RNA polymerase I transcription factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003701 RNA polymerase I transcription factor activity OBSOLETE. Functions to initiate or regulate RNA polymerase I transcription. CHEBI:29888 diphosphoric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29888 NCBITaxon:3312 Coniferophyta organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_3312 conifers GO:1904469 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1904469 GO:0062022 mitotic cohesin ssDNA (lagging strand) loading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062022 second-DNA capture The ATP-dependent protein localization to chromatin by which a cohesin ring complex is topologically linked to ssDNA (lagging strand) which is already linked to a dsDNA (leading strand) molecule as part of the mitotic cell cycle. GO:1904468 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1904468 GO:0062021 mitotic cohesin dsDNA (leading strand) loading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062021 The protein localization to chromatin by which a cohesin ring complex is topologically linked to dsDNA (leading strand) as part of the mitotic cell cycle. GO:1904467 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1904467 GO:1904466 positive regulation of matrix metallopeptidase secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904466 up-regulation of matrix metallopeptidase secretion|upregulation of matrix metalloproteinase secretion|up-regulation of MMP secretion|upregulation of matrix metallopeptidase secretion|up-regulation of matrix metalloproteinase secretion|upregulation of MMP secretion|activation of matrix metalloproteinase secretion|up regulation of matrix metallopeptidase secretion|positive regulation of matrix metalloproteinase secretion|activation of matrix metallopeptidase secretion|up regulation of matrix metalloproteinase secretion|up regulation of MMP secretion|activation of MMP secretion|positive regulation of MMP secretion Any process that activates or increases the frequency, rate or extent of matrix metallopeptidase secretion. GO:1904465 negative regulation of matrix metallopeptidase secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904465 down regulation of matrix metalloproteinase secretion|inhibition of matrix metallopeptidase secretion|inhibition of MMP secretion|inhibition of matrix metalloproteinase secretion|down regulation of matrix metallopeptidase secretion|down regulation of MMP secretion|downregulation of matrix metallopeptidase secretion|down-regulation of matrix metalloproteinase secretion|negative regulation of matrix metalloproteinase secretion|downregulation of MMP secretion|down-regulation of matrix metallopeptidase secretion|downregulation of matrix metalloproteinase secretion|negative regulation of MMP secretion|down-regulation of MMP secretion Any process that stops, prevents or reduces the frequency, rate or extent of matrix metallopeptidase secretion. GO:0062023 collagen-containing extracellular matrix biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062023 An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells. GO:1904475 regulation of small GTPase binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904475 regulation of Ras GTPase binding Any process that modulates the frequency, rate or extent of small GTPase binding. GO:0062026 negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062026 Any process that stops or decreases the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome. GO:1904474 cellular response to L-dopa biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904474 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-dopa stimulus. GO:0062025 regulation of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062025 Any process that modualtes the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome. CHEBI:39206 dibenzopyridine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39206 GO:1904473 response to L-dopa biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904473 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-dopa stimulus. GO:0062028 regulation of stress granule assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062028 Any process that modulates the rate, frequency or extent of stress granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule. CHEBI:39205 dibenzopyrrole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39205 GO:1904472 positive regulation of endothelin production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904472 activation of endothelin-3 secretion|activation of endothelin-2 secretion|activation of endothelin-1 secretion|up-regulation of endothelin secretion|positive regulation of endothelin-3 secretion|positive regulation of endothelin-2 secretion|activation of endothelin secretion|up regulation of endothelin-3 secretion|upregulation of EDN3 secretion|positive regulation of endothelin-1 secretion|up regulation of endothelin-2 secretion|upregulation of EDN2 secretion|upregulation of EDN1 secretion|up regulation of endothelin-1 secretion|up-regulation of EDN3 secretion|up-regulation of EDN2 secretion|upregulation of endothelin-3 secretion|upregulation of endothelin-2 secretion|up regulation of endothelin secretion|up-regulation of EDN1 secretion|upregulation of endothelin-1 secretion|activation of EDN3 secretion|activation of EDN2 secretion|activation of EDN1 secretion|up-regulation of endothelin-3 secretion|positive regulation of EDN3 secretion|up-regulation of endothelin-2 secretion|positive regulation of EDN2 secretion|positive regulation of endothelin secretion|upregulation of endothelin secretion|up-regulation of endothelin-1 secretion|positive regulation of EDN1 secretion|up regulation of EDN3 secretion|up regulation of EDN2 secretion|up regulation of EDN1 secretion Any process that activates or increases the frequency, rate or extent of endothelin production. GO:0062027 positive regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062027 Any process that starts or increases the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome. GO:1904471 negative regulation of endothelin production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904471 downregulation of EDN2 secretion|down-regulation of endothelin-3 secretion|negative regulation of endothelin-3 secretion|down-regulation of endothelin-2 secretion|negative regulation of endothelin-2 secretion|downregulation of EDN1 secretion|negative regulation of endothelin-1 secretion|down-regulation of endothelin-1 secretion|down regulation of EDN3 secretion|down regulation of EDN2 secretion|down regulation of EDN1 secretion|downregulation of endothelin-3 secretion|inhibition of EDN3 secretion|downregulation of endothelin-2 secretion|inhibition of EDN2 secretion|downregulation of endothelin-1 secretion|down-regulation of endothelin secretion|inhibition of EDN1 secretion|down regulation of endothelin-3 secretion|down regulation of endothelin-2 secretion|down regulation of endothelin-1 secretion|inhibition of endothelin-3 secretion|downregulation of endothelin secretion|inhibition of endothelin-2 secretion|inhibition of endothelin-1 secretion|negative regulation of EDN3 secretion|down-regulation of EDN3 secretion|negative regulation of EDN2 secretion|down-regulation of EDN2 secretion|negative regulation of endothelin secretion|down-regulation of EDN1 secretion|negative regulation of EDN1 secretion|down regulation of endothelin secretion|inhibition of endothelin secretion|downregulation of EDN3 secretion Any process that stops, prevents or reduces the frequency, rate or extent of endothelin production. CHEBI:15258 trichlorophenols biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15258 GO:1904470 regulation of endothelin production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904470 regulation of EDN3 secretion|regulation of endothelin secretion|regulation of EDN2 secretion|regulation of EDN1 secretion|regulation of endothelin-3 secretion|regulation of endothelin-2 secretion|regulation of endothelin-1 secretion Any process that modulates the frequency, rate or extent of endothelin production. GO:0062029 positive regulation of stress granule assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062029 Any process that starts or increases the rate, frequency or extent of stress-granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule. CHEBI:39208 antibiotic insecticide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39208 GO:0003708 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003708 GO:0003707 steroid hormone receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003707 Combining with a steroid hormone and transmitting the signal within the cell to initiate a change in cell activity or function. GO:0003709 obsolete RNA polymerase III transcription factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003709 RNA polymerase III transcription factor activity OBSOLETE. Functions to initiate or regulate RNA polymerase III transcription. GO:0003704 obsolete specific RNA polymerase II transcription factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003704 specific RNA polymerase II transcription factor activity OBSOLETE. Functions to enable the transcription of specific, or specific sets, of genes by RNA polymerase II. CHEBI:39203 dibenzopyran biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39203 GO:0003703 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003703 GO:0003706 obsolete ligand-regulated transcription factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003706 ligand-regulated transcription factor activity OBSOLETE. Functions to enable the transcription of specific, or specific sets, of genes by RNA polymerase II in response to a ligand. CHEBI:39201 phenazines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39201 GO:0003705 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003705 CHEBI:30848 urate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30848 CHEBI:30845 2-furoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30845 CHEBI:30844 hydroxymalonate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30844 CHEBI:30843 oxomalonate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30843 CHEBI:30842 oxomalonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30842 CHEBI:30841 3-hydroxypyruvic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30841 GO:0062051 lipopolysaccharide transport system biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062051 A protein-containing complex that functions to transport lipopolysaccharide from its site of synthesis at the cytoplasmic membrane across the periplasm to the outer membrane in an ATP-dependent manner. CHEBI:29850 arsonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29850 GO:0062050 GPI-mannose ethanolamine phosphate phosphodiesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062050 A phosphoric diester hydrolase activity that removes the ethanolamine phosphate from mannose 2 of a GPI anchor. CHEBI:29852 methylarsonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29852 GO:0062052 starch granule initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062052 The sequence of events that initiates (or primes) the synthesis of semi-crystalline starch granules within photosynthetic chloroplasts or non-photosynthetic amyloplasts. GO:1904479 negative regulation of intestinal absorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904479 down regulation of intestinal absorption|downregulation of intestinal absorption|down-regulation of intestinal absorption|inhibition of intestinal absorption Any process that stops, prevents or reduces the frequency, rate or extent of intestinal absorption. GO:0086019 cell-cell signaling involved in cardiac conduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086019 cell-cell signalling involved in cardiac conduction Any process that mediates the transfer of information from one cell to another and contributes to the heart process that regulates cardiac muscle contraction; beginning with the generation of an action potential in the sinoatrial node and ending with regulation of contraction of the myocardium. GO:0062055 photosynthetic state transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062055 A regulation of the phtosynthetic light reaction in which the light harvesting antenna complexes transition between photosystems. GO:0086018 SA node cell to atrial cardiac muscle cell signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086018 sinoatrial node cardiomyocyte to atrial cardiomyocyte signalling|SAN cardiomyocyte to atrial cardiomyocyte signalling|SA node cardiac muscle cell to atrial cardiac muscle cell signalling|sinus node cardiomyocyte to atrial cardiomyocyte signalling|SA node cardiomyocyte to atrial cardiomyocyte signalling Any process that mediates the transfer of information from an SA node cardiomyocyte to an atrial cardiomyocyte. GO:1904478 regulation of intestinal absorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904478 Any process that modulates the frequency, rate or extent of intestinal absorption. GO:0062054 fluoride channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062054 Enables the facilitated diffusion of fluoride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. GO:1904477 positive regulation of small GTPase binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904477 activation of Ras GTPase binding|up-regulation of small GTPase binding|up regulation of small GTPase binding|positive regulation of Ras GTPase binding|upregulation of small GTPase binding Any process that activates or increases the frequency, rate or extent of small GTPase binding. GO:0062057 L-aspartate:fumarate antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062057 Enables the transport of L-aspartate and fumarate across a membrane according to the reaction L-aspartate (out) + fumarate (in) = L-aspartate (in) + fumarate (out). GO:0086017 Purkinje myocyte action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086017 An action potential that occurs in a Purkinje myocyte. GO:1904476 negative regulation of small GTPase binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904476 inhibition of small GTPase binding|down-regulation of Ras GTPase binding|negative regulation of Ras GTPase binding|downregulation of small GTPase binding|down regulation of small GTPase binding Any process that stops, prevents or reduces the frequency, rate or extent of small GTPase binding. GO:0062056 compound eye pigment cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062056 The process in which a relatively unspecialized cell acquires the specialized features of a compound eye pigment cell, a cell of the retina containing screening pigments that functions to screen photoreceptors from light leaking from adjacent ommatidia. GO:0086016 AV node cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086016 atrioventricular node cardiac muscle cell action potential|AV node cardiac muscle cell action potential An action potential that occurs in an atrioventricular node cardiac muscle cell. CHEBI:30849 L-arabinose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30849 GO:0086015 SA node cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086015 sinus node cardiac muscle cell action potential|SA node cardiac muscle cell action potential|sinoatrial node cardiac muscle cell action potential|SAN cardiac muscle cell action potential An action potential that occurs in a sinoatrial node cardiac muscle cell. GO:1904486 response to 17alpha-ethynylestradiol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904486 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 17alpha-ethynylestradiol stimulus. GO:0062059 FACT complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062059 Interacting selectively and non-covalently with a FACT complex. GO:0086014 atrial cardiac muscle cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086014 An action potential that occurs in an atrial cardiac muscle cell. GO:0062058 transcription factor TFIIH holo complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062058 Interacting selectively and non-covalently with a transcription factor TFIIH holo complex. GO:1904484 cloacal gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904484 The process whose specific outcome is the progression of a cloacal gland over time, from its formation to the mature structure. GO:0086013 membrane repolarization during cardiac muscle cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086013 The process in which ions are transported across a membrane such that the cardiac muscle cell plasma membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential. GO:0086012 membrane depolarization during cardiac muscle cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086012 The process in which cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential. GO:1904483 synthetic cannabinoid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1904483 Interacting selectively and non-covalently with synthetic cannabinoid. CHEBI:15208 taxuyunnanin C biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15208 GO:0086011 membrane repolarization during action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086011 The process in which ions are transported across a membrane such that the membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential. GO:1904482 cellular response to tetrahydrofolate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904482 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrahydrofolate stimulus. GO:0086010 membrane depolarization during action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086010 The process in which membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential. GO:1904481 response to tetrahydrofolate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904481 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrahydrofolate stimulus. GO:1904480 positive regulation of intestinal absorption biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904480 up-regulation of intestinal absorption|upregulation of intestinal absorption|up regulation of intestinal absorption|activation of intestinal absorption Any process that activates or increases the frequency, rate or extent of intestinal absorption. NCBITaxon:3372 Gnetopsida organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_3372 Gneticae|Chlamydospermopsida CHEBI:30859 3-maleylpyruvic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30859 CHEBI:29866 arsenite(3-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29866 CHEBI:30854 indole-3-acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30854 CHEBI:30853 glycyrrhetinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30853 NCBITaxon:3378 Gnetales organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_3378 CHEBI:30852 galactaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30852 GO:0062040 fungal biofilm matrix biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062040 An extracellular matrix lying external to fungal cells. The fungal biofilm matrix consists of polysaccharides, proteins, lipids, and nucleic acids. Fungal biofilms mediate adherence to host tissues, and provide protection from host immune defenses. GO:0062042 regulation of cardiac epithelial to mesenchymal transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062042 Any process that modulates the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. CHEBI:29864 mannitol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29864 GO:0062041 positive regulation of meiotic sister chromatid arm separation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062041 Any process that increases the rate or exent of meiotic sister chromatid arm separation, the cell cycle process in which sister chromatid arms are physically detached from each other during meiosis. GO:0086009 membrane repolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086009 The process in which ions are transported across a membrane such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential. GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0086008 Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a cardiac muscle cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. GO:0062044 negative regulation of cardiac epithelial to mesenchymal transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062044 Any process that stops or decreases the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. GO:1904489 regulation of reactive oxygen species metabolic process by negative regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904489 regulation of ROS metabolic process by down-regulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by down regulation of global transcription from RNA polymerase II promoter|regulation of ROS metabolic process by negative regulation of transcription from Pol II promoter|regulation of reactive oxygen species metabolic process by down regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by inhibition of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by negative regulation of gene-specific transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by downregulation of transcription from RNA polymerase II promoter|regulation of ROS metabolic process by inhibition of transcription from RNA polymerase II promoter|regulation of ROS metabolic process by negative regulation of global transcription from Pol II promoter|regulation of reactive oxygen species metabolism by down-regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by inhibition of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by negative regulation of transcription from RNA polymerase II promoter|regulation of ROS metabolic process by negative regulation of transcription from RNA polymerase II promoter, global|regulation of reactive oxygen species metabolic process by negative regulation of gene-specific transcription from RNA polymerase II promoter|regulation of ROS metabolic process by downregulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by down-regulation of global transcription from RNA polymerase II promoter|regulation of ROS metabolic process by down regulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by negative regulation of transcription from Pol II promoter|regulation of ROS metabolic process by down regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by down-regulation of transcription from RNA polymerase II promoter|regulation of ROS metabolic process by downregulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by down-regulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by inhibition of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by negative regulation of global transcription from Pol II promoter|regulation of reactive oxygen species metabolism by negative regulation of transcription from Pol II promoter|regulation of ROS metabolic process by inhibition of global transcription from RNA polymerase II promoter|regulation of ROS metabolic process by negative regulation of gene-specific transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by negative regulation of transcription from RNA polymerase II promoter, global|regulation of reactive oxygen species metabolism by downregulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by inhibition of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by down regulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by negative regulation of global transcription from Pol II promoter|regulation of ROS metabolic process by negative regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by down regulation of transcription from RNA polymerase II promoter|regulation of ROS metabolic process by down-regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by negative regulation of transcription from RNA polymerase II promoter, global|regulation of reactive oxygen species metabolic process by downregulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by downregulation of global transcription from RNA polymerase II promoter A negative regulation of transcription from RNA polymerase II promoter that results in regulation of reactive oxygen species metabolic process. GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0086007 Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of a cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. GO:0062043 positive regulation of cardiac epithelial to mesenchymal transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062043 Any process that starts or increases the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. GO:1904488 regulation of reactive oxygen species metabolic process by positive regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904488 regulation of ROS metabolic process by stimulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by positive regulation of gene-specific transcription from RNA polymerase II promoter|regulation of ROS metabolic process by activation of global transcription from RNA polymerase II promoter|regulation of ROS metabolic process by positive regulation of global transcription from Pol II promoter|regulation of reactive oxygen species metabolism by up regulation of transcription from RNA polymerase II promoter|regulation of ROS metabolic process by up-regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by positive regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by upregulation of global transcription from RNA polymerase II promoter|regulation of ROS metabolic process by positive regulation of transcription from Pol II promoter|regulation of reactive oxygen species metabolism by stimulation of global transcription from RNA polymerase II promoter|regulation of ROS metabolic process by positive regulation of transcription from RNA polymerase II promoter, global|regulation of reactive oxygen species metabolic process by up-regulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by positive regulation of gene-specific transcription from RNA polymerase II promoter|regulation of ROS metabolic process by up regulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by activation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by up regulation of transcription from RNA polymerase II promoter|regulation of ROS metabolic process by upregulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by up-regulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by stimulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by activation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by activation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by up-regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by positive regulation of global transcription from Pol II promoter|regulation of ROS metabolic process by upregulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by positive regulation of transcription from Pol II promoter|regulation of ROS metabolic process by stimulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by up regulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by stimulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by positive regulation of transcription from RNA polymerase II promoter, global|regulation of ROS metabolic process by positive regulation of gene-specific transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by activation of global transcription from RNA polymerase II promoter|regulation of ROS metabolic process by up regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by positive regulation of global transcription from Pol II promoter|regulation of reactive oxygen species metabolic process by up-regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by upregulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by positive regulation of transcription from Pol II promoter|regulation of ROS metabolic process by positive regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by positive regulation of transcription from RNA polymerase II promoter, global|regulation of ROS metabolic process by up-regulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by up regulation of global transcription from RNA polymerase II promoter|regulation of ROS metabolic process by activation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by upregulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by stimulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by upregulation of global transcription from RNA polymerase II promoter A positive regulation of transcription from RNA polymerase II promoter that results in regulation of reactive oxygen species metabolic process. GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0086006 Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. GO:0062046 dehydropipecolic acid reductase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062046 Catalysis of the reaction: dehydropipecolic acid + NAD(P)H + H+ = L-pipecolic acid + NAD(P)+. GO:1904487 cellular response to 17alpha-ethynylestradiol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904487 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 17alpha-ethynylestradiol stimulus. GO:0062045 L-lysine alpha-aminotransferase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062045 Catalysis of the reaction: L-lysine + pyruvate= epsilon-amino-alpha-ketocaproic acid (KAC) + alanine. GO:0086005 ventricular cardiac muscle cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086005 An action potential that occurs in a ventricular cardiac muscle cell. GO:1904497 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1904497 GO:0086004 regulation of cardiac muscle cell contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086004 Any process that modulates the frequency, rate or extent of cardiac muscle cell contraction. GO:0062048 lymphotoxin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062048 lymphotoxin alpha-beta A homo- or heterotrimeric protein containing complex consisting of alpha and beta lymphotoxin subunits in different stoichiometric combinations. GO:0086003 cardiac muscle cell contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086003 The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a cardiac muscle cell. GO:0062047 pipecolic acid N-hydroxylase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062047 Catalysis of the reaction: L-pipecolic acid + NAD(P)H + O2 + H+ = N-hydroxypipecolic acid + NAD(P)+ + H2O. GO:1904496 positive regulation of substance P secretion, neurotransmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904496 up regulation of substance P secretion, neurotransmission|upregulation of substance P secretion, neurotransmission|up-regulation of substance P secretion, neurotransmission|activation of substance P secretion, neurotransmission Any process that activates or increases the frequency, rate or extent of substance P secretion, neurotransmission. GO:1904495 negative regulation of substance P secretion, neurotransmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904495 down-regulation of substance P secretion, neurotransmission|downregulation of substance P secretion, neurotransmission|down regulation of substance P secretion, neurotransmission|inhibition of substance P secretion, neurotransmission Any process that stops, prevents or reduces the frequency, rate or extent of substance P secretion, neurotransmission. GO:0086002 cardiac muscle cell action potential involved in contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086002 An action potential that occurs in a cardiac muscle cell and is involved in its contraction. GO:1904494 regulation of substance P secretion, neurotransmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904494 Any process that modulates the frequency, rate or extent of substance P secretion, neurotransmission. GO:0086001 cardiac muscle cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086001 An action potential that occurs in a cardiac muscle cell. GO:0062049 protein phosphatase inhibitor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062049 ComplexPortal:CPX-1620 A protein-containing complex that inhibits protein phosphatase activity by directly binding to a protein phosphatase. GO:1904493 tetrahydrofolyl-poly(glutamate) polymer binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1904493 Interacting selectively and non-covalently with tetrahydrofolyl-poly(glutamate) polymer. GO:1904492 Ac-Asp-Glu binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1904492 Interacting selectively and non-covalently with Ac-Asp-Glu. GO:1904491 protein localization to ciliary transition zone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904491 protein localization in ciliary transition zone|protein localisation in ciliary transition zone|protein localisation to ciliary transition zone A process in which a protein is transported to, or maintained in, a location within a ciliary transition zone. GO:1904490 negative regulation of mitochondrial unfolded protein response by negative regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904490 negative regulation of mitochondrial unfolded protein response by down regulation of global transcription from RNA polymerase II promoter|negative regulation of mtUPR by down regulation of global transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by negative regulation of global transcription from Pol II promoter|negative regulation of mtUPR by negative regulation of global transcription from Pol II promoter|negative regulation of mtUPR by downregulation of transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by downregulation of transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by negative regulation of transcription from RNA polymerase II promoter, global|negative regulation of mtUPR by negative regulation of transcription from RNA polymerase II promoter, global|negative regulation of mitochondrial unfolded protein response by downregulation of global transcription from RNA polymerase II promoter|negative regulation of mtUPR by downregulation of global transcription from RNA polymerase II promoter|negative regulation of mtUPR by down regulation of transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by down regulation of transcription from RNA polymerase II promoter|negative regulation of mtUPR by inhibition of global transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by inhibition of global transcription from RNA polymerase II promoter|negative regulation of mtUPR by negative regulation of gene-specific transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by negative regulation of gene-specific transcription from RNA polymerase II promoter|negative regulation of mtUPR by down-regulation of global transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by down-regulation of global transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by negative regulation of transcription from Pol II promoter|negative regulation of mtUPR by negative regulation of transcription from Pol II promoter|negative regulation of mtUPR by negative regulation of transcription from RNA polymerase II promoter|negative regulation of mtUPR by down-regulation of transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by down-regulation of transcription from RNA polymerase II promoter|negative regulation of mtUPR by inhibition of transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by inhibition of transcription from RNA polymerase II promoter A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of mitochondrial unfolded protein response. CHEBI:30851 keto-phenylpyruvic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30851 CHEBI:30850 3-propylmalic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30850 CHEBI:30825 elaidate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30825 CHEBI:30823 oleate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30823 CHEBI:29838 disulfanidyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29838 GO:0062071 Pi Mi complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062071 A transcription factor complex composed of a homeodomain protein and the M-specific peptide Mi that acts at the regulatory region of genes required for the activation of meiosis. CHEBI:30820 2-oxooctadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30820 GO:0062070 SAGA complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062070 Interacting selectively and non-covalently with a SAGA complex. OIO:hasDbXref database_cross_reference biolink:OntologyClass go-plus http://www.geneontology.org/formats/oboInOwl#hasDbXref GO:0062073 histone mRNA stem-loop binding complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062073 ComplexPortal:CPX-1305|ComplexPortal:CPX-1313|ComplexPortal:CPX-1312|ComplexPortal:CPX-1311 SLBP-MIF4GD complex|SLBP-SLIP1 complex A protein-containing complex composed of a stem-loop binding protein (in most species SLBP) and its interacting partner (SLIP1 or MIF4GD in most species) that binds to the histone mRNA (hmRNA) 3-prime-stem-loop structure. Facilitates hmRNA translation initiation and may also be involved in its processing and nuclear export. GO:0062072 H3K9me3 modified histone binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062072 Interacting selectively and non-covalently with a histone H3 in which the lysine residue at position 9 has been modified by trimethylation. GO:0062075 pollen aperture formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062075 The cellular component assembly process of forming pollen apertures, areas where exine is reduced or absent, in the pollen cell wall. GO:0062074 pollen aperture biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062074 An area where exine is reduced or absent, in the pollen wall. GO:0062077 phenylacetyl-CoA 1,2-epoxidase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062077 ComplexPortal:CPX-2844 paaABCE complex A protein complex capable of catalysing the reaction: phenylacetyl-CoA + H(+) + NADPH + O2 = 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + H2O + NADP(+). GO:0062076 acyl-CoA delta5-desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062076 EC:1.14.19.44 acyl-CoA delta(5)-desaturase activity|Acyl-CoA (8-3)-desaturase|acyl-CoA D5-desaturase activity Catalysis of the reaction: acyl-CoA + reduced acceptor + O2 = delta5-acyl-CoA + acceptor + 2 H2O. GO:1904499 obsolete regulation of chromatin-mediated maintenance of transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904499 OBSOLETE. Any process that modulates the frequency, rate or extent of chromatin-mediated maintenance of transcription. GO:0086039 calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0086039 Enables the transfer of a solute or solutes from one side of a cardiac muscle cell plasma membrane to the other according to the reaction: ATP + H2O + Ca2+(cis) = ADP + phosphate + Ca2+(trans). The transfer contributes to the regulation of the plasma membrane potential. GO:0062079 ATG2-ATG18 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062079 ComplexPortal:CPX-361 A protein complex essential for autophagy during nutrient deprivation, a catabolic process that sequesters undesired cellular material into autophagosomes for delivery to lysosomes for degradation. Contributes to nutrition homeostasis and damage control in eukaryotic cells. Functions at a late step of autophagosome formation for efficient completion of sequestration, probably through facilitating recruitment of ATG8-phosphatidylethanolamine (PE) to the preautophagosomal structure (PAS) and/or its protection from deconjugation by ATG4. Composed of ATG2 and ATG18 in Saccharomyces cerevisiae. CHEBI:30828 trans-vaccenate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30828 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0086038 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + Na+(out) = Ca2+(out) + Na+(in), which contributes to regulating the membrane potential of a cardiac muscle cell. GO:1904498 protein localization to mitotic actomyosin contractile ring biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904498 protein localization to actomyosin contractile ring involved in mitotic cytokinesis|protein localization to actomyosin contractile ring involved in cytokinesis after mitosis|protein localization to actomyosin contractile ring during mitotic cytokinesis|protein localisation to actomyosin contractile ring involved in cytokinesis after mitosis|protein localization to mitotic actomyosin contractile ring|protein localisation to actomyosin contractile ring involved in mitotic cytokinesis Any protein localization to actomyosin contractile ring that is involved in mitotic cytokinesis. GO:0062078 TSC1-TSC2 complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062078 tuberin sclerosis complex binding|tuberin-hamartin complex binding Interacting selectively and non-covalently with a TSC1-TSC2 complex. CHEBI:30827 cis-vaccenate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30827 GO:0086037 sodium:potassium-exchanging ATPase activity involved in regulation of cardiac muscle cell membrane potential biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0086037 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) + K+(out) = ADP + phosphate + Na+(out) + K+(in), that contributes to regulating the membrane potential of a cardiac muscle cell. GO:0086036 regulation of cardiac muscle cell membrane potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086036 Any process that modulates the establishment or extent of a membrane potential in a cardiac muscle cell (a cardiomyocyte). A membrane potential is the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. GO:0086033 G protein-coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086033 G-protein coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate|muscarinic acetylcholine receptor signaling pathway involved in negative regulation of heart rate|muscarinic receptor signalling pathway involved in negative regulation of heart rate|M2 receptor signalling pathway involved in negative regulation of heart rate A G protein-coupled acetylcholine receptor signaling pathway that contributes to a decrease in frequency or rate of heart contraction. Binding of acetylcholine to a G protein-coupled (muscarinic) receptor on the surface of the signal-receiving cell results in the alpha subunit of a coupled G-protein binding to GTP. This results in the separation of the beta-gamma complex from the alpha subunit. Both the alpha subunit, and the beta-gamma complex can continue to signal to bring about membrane hyperpolarization and a reduction in heart rate. GO:0086030 adenylate cyclase-activating adrenergic receptor signaling pathway involved in cardiac muscle relaxation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086030 adrenergic receptor signaling pathway involved in cardiac muscle relaxation via activation of AC|adrenergic receptor-induced cardiac relaxation|adrenergic receptor signaling pathway involved in cardiac muscle relaxation|Gs-coupled adrenergic receptor signaling pathway involved in cardiac muscle relaxation|adenylate cyclase-activating adrenergic receptor signaling pathway involved in cardiac muscle relaxation An adrenergic receptor signaling pathway that contributes to a reduction in cardiac muscle contraction. Beta-adrenergic receptor-induced cardiac relaxation is achieved by a GPCR-activated adenylate cyclase generating cAMP; cAMP then activates the cAMP-dependent protein kinase A (PKA), which phosphorylates the sarcoplasmic reticulum (SR) membrane protein PLB. In its non-phosphorylated state, PLB acts as an inhibitor of the ATPase Ca(2+) pump of the cardiac SR (SERCA2a); inhibition of the pump is relieved upon phosphorylation. The pump removes Ca(2+) from the cytoplasm, thereby preventing cytosolic Ca(2+)-dependent activation of contractile proteins, leading to enhanced muscle relaxation. CHEBI:15226 tetrathionate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15226 CHEBI:8695 quercetagetin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_8695 CHEBI:30837 allantoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30837 CHEBI:29847 arsonous acid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29847 CHEBI:30835 2-methylcitric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30835 CHEBI:30833 adipate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30833 CHEBI:30832 adipic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30832 GO:0062060 NuA4 histone acetyltransferase complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062060 Interacting selectively and non-covalently with a NuA4 histone acetyltransferase complex. CHEBI:29846 arsinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29846 CHEBI:30831 2-oxobutanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30831 CHEBI:30830 4-hydroxybutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30830 GO:0062062 oligosaccharyltransferase complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062062 Interacting selectively and non-covalently with an oligosaccharyltransferase complex. CHEBI:29840 arsinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29840 GO:0062061 TAP complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062061 Interacting selectively and non-covalently with a TAP complex. GO:0062064 box C/D snoRNP complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062064 Interacting selectively and non-covalently with a box C/D snoRNP complex. GO:0062063 BBSome binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062063 Interacting selectively and non-covalently with a BBSome complex. GO:0062066 PSII associated light-harvesting complex II binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062066 Interacting selectively and non-covalently with a PSII associated light-harvesting complex II. GO:0062065 box H/ACA snoRNP complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062065 Interacting selectively and non-covalently with a box H/ACA snoRNP complex. GO:0086029 Purkinje myocyte to ventricular cardiac muscle cell signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086029 Purkinje myocyte to ventricular cardiac muscle cell signalling Any process that mediates the transfer of information from a Purkinje myocyte to a ventricular cardiac muscle cell. GO:0062068 chloroplast photosystem II binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062068 Interacting selectively and non-covalently with a chloroplast photosystem II. GO:0086028 bundle of His cell to Purkinje myocyte signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086028 bundle of His cardiac muscle cell to Purkinje myocyte signalling|bundle of His cardiac muscle cell to Purkinje myocyte signaling Any process that mediates the transfer of information from a bundle of His cardiomyocyte to a Purkinje myocyte. CHEBI:30839 orotate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30839 GO:0062067 chloroplast photosystem I binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062067 Interacting selectively and non-covalently with a chloroplast photosystem I. GO:0086027 AV node cell to bundle of His cell signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086027 AV node cell to bundle of His cell signalling|atrioventricular node to bundle of His cell signaling Any process that mediates the transfer of information from an AV node cardiac muscle cell to a bundle of His cardiomyocyte. CHEBI:30838 itaconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30838 GO:0086026 atrial cardiac muscle cell to AV node cell signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086026 atrial cardiomyocyte to atrioventricular node cell signaling|atrial cardiomyocyte to AV node cell signaling|atrial cardiomyocyte to AV node cell signalling Any process that mediates the transfer of information from an atrial cardiomyocyte to an AV node cell. GO:0062069 GARP complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062069 Interacting selectively and non-covalently with a GARP complex. GO:0086024 adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086024 Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|adrenergic receptor signaling pathway involved in positive regulation of heart rate|adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|activation of funny current by beta-adrenergic receptor signaling pathway|beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|adrenergic receptor signalling pathway involved in positive regulation of heart rate|If activation by beta-adrenergic receptor signaling pathway An adrenergic receptor signaling pathway that contributes to an increase in frequency or rate of heart contraction. Binding of adrenalin or noradrenalin to a beta-adrenergic receptor on the surface of the signal-receiving cell results in the activation of an intracellular Gs protein. Gs activates adenylate cyclase to increase intracellular cyclic-AMP (cAMP) levels. cAMP binds directly to F-channels to allow an inward flow of sodium (known as funny current, or If current). The funny current is responsible for membrane depolarization and an increase in heart rate. GO:0086023 adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086023 beta-adrenergic receptor signalling pathway involved in heart process|adrenergic receptor signalling pathway involved in heart process|adrenergic receptor signaling pathway involved in heart process A series of molecular signals beginning with a G protein-coupled adrenergic cell surface receptor combining with epinephrine or norepinephrine, to activate adenylate cyclase, which contributes to a circulatory system process carried out by the heart. GO:0086022 SA node cell-atrial cardiac muscle cell adhesion involved in cell communication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086022 sinoatrial node cardiomyocyte-atrial cardiomyocyte adhesion involved in cell communication|SAN cardiomyocyte-atrial cardiomyocyte adhesion involved in cell communication|sinus node cardiomyocyte-atrial cardiomyocyte adhesion involved in cell communication|SA cardiomyocyte-atrial cardiomyocyte adhesion involved in cell communication|SA cardiac muscle cell-atrial cardiac muscle cell adhesion involved in cell communication The attachment of SA node cardiomyocyte to an atrial cardiomyocyte via adhesion molecules that results in the cells being juxtaposed so that they can communicate. GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086021 SA node cardiac muscle cell to atrial cardiac muscle cell communication by electrical coupling|sinus node cardiomyocyte to atrial cardiomyocyte communication by electrical coupling|SA node cardiomyocyte to atrial cardiomyocyte communication by electrical coupling|sinoatrial node cardiomyocyte to atrial cardiomyocyte communication by electrical coupling|SAN cardiomyocyte to atrial cardiomyocyte communication by electrical coupling The process that mediates signaling interactions between an SA node cardiomyocyte and an atrial cardiomyocyte by transfer of current between their adjacent cytoplasms via intercellular protein channels. GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0086020 gap junction channel activity involved in sinus node cell-atrial cardiomyocyte electrical coupling|gap junction channel activity involved in sinoatrial node cell-atrial cardiomyocyte electrical coupling|gap junction channel activity involved in SA node cell-atrial cardiomyocyte electrical coupling|gap junction channel activity involved in SAN cell-atrial cardiomyocyte electrical coupling A wide pore channel activity that enables a direct cytoplasmic connection from an SA node cell to an atrial cardiomyocyte. The gap junction passes electrical signals between the cells contributing to cardiac conduction. GO:0003678 DNA helicase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003678 Reactome:R-HSA-5693589|EC:3.6.4.12 ATP-dependent DNA helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of the DNA helix. GO:0052601 (S)-limonene 1,2-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052601 KEGG_REACTION:R09385|KEGG_REACTION:R09389|EC:1.14.13.107|MetaCyc:RXN-9409 (-)-limonene 1,2-monooxygenase activity|(S)-limonene,NAD(P)H:oxygen oxidoreductase activity|(-)-limonene,NAD(P)H:oxygen oxidoreductase activity Catalysis of the reaction: (4S)-limonene + NAD(P)H + H+ + O2 = NAD(P)+ + H2O + (4S)-limonene-1,2-epoxide. GO:0003677 DNA binding biolink:MolecularActivity go-plus goslim_flybase_ribbon|goslim_chembl|goslim_mouse|goslim_agr|goslim_yeast|goslim_candida|goslim_plant|goslim_drosophila|goslim_aspergillus|goslim_generic http://purl.obolibrary.org/obo/GO_0003677 structure specific DNA binding|microtubule/chromatin interaction|plasmid binding|structure-specific DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). GO:0052600 propane-1,3-diamine oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052600 RHEA:30895|EC:1.4.3.22|KEGG_REACTION:R03139|MetaCyc:RXN-6381 trimethylenediamine oxidase activity|1,3-diaminopropane oxidase activity|propane-1,3-diamine:oxygen oxidoreductase (deaminating) activity Catalysis of the reaction: propane-1,3-diamine + H2O + O2 = 3-aminopropanal + NH3 + hydrogen peroxide + H+. GO:0003679 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003679 GO:0003674 molecular_function biolink:MolecularActivity go-plus goslim_chembl|goslim_candida|goslim_yeast|goslim_pir|goslim_plant|goslim_aspergillus|goslim_metagenomics|goslim_generic http://purl.obolibrary.org/obo/GO_0003674 molecular function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. These actions are described from two distinct but related perspectives: (1) biochemical activity, and (2) role as a component in a larger system/process. GO:0052605 gamma-tocopherol cyclase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052605 KEGG_REACTION:R07502|RHEA:37983|MetaCyc:RXN-2543 Catalysis of the reaction: 2,3-dimethyl-6-phytyl-1,4-benzoquinone = gamma-tocopherol. GO:0052604 delta-tocopherol cyclase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052604 MetaCyc:RXN-2561|RHEA:37987|KEGG_REACTION:R07503 Catalysis of the reaction: 2-methyl-6-phytyl-1,4-benzoquinone = delta-tocopherol. GO:0003673 obsolete Gene_Ontology biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0003673 Gene_Ontology OBSOLETE. A controlled vocabulary that can be applied to all organisms even as knowledge of gene and protein roles in cells is accumulating and changing. GO provides three structured networks of defined terms to describe gene product attributes. GO:0003676 nucleic acid binding biolink:MolecularActivity go-plus goslim_chembl|goslim_pir|goslim_plant|goslim_metagenomics http://purl.obolibrary.org/obo/GO_0003676 base pairing Interacting selectively and non-covalently with any nucleic acid. GO:0052603 1-chloro-4-nitrosobenzene nitroreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052603 UM-BBD_enzymeID:e0245|MetaCyc:RXN-8834 Catalysis of the reaction: 1-chloro-4-nitrosobenzene + NADPH + H+ = 1-chloro-4-hydroxylaminobenzene + NADP+ + H2O. GO:0003675 obsolete protein biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0003675 protein OBSOLETE. (Was not defined before being made obsolete). GO:0052602 4-chloronitrobenzene nitroreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052602 UM-BBD_enzymeID:e0245|MetaCyc:RXN-8833 Catalysis of the reaction: 4-chloronitrobenzene + NADPH + H+ = 1-chloro-4-nitrosobenzene + NADP+ + H2O. GO:0052609 4-ketotorulene 3-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052609 MetaCyc:RXN-8218|EC:1.14.99.- beta-ring carotenoid 3-hydroxylase activity|beta-carotene hydroxylase activity|carotene beta-ring hydroxylase activity Catalysis of the reaction: 4-ketotorulene + a reduced electron acceptor + oxygen = 3-hydroxy-4-ketotorulene + an oxidized electron acceptor + H2O. GO:0052608 echinenone 3-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052608 MetaCyc:RXN-8214|EC:1.14.99.- beta-ring carotenoid 3-hydroxylase activity|beta-carotene hydroxylase activity|carotene beta-ring hydroxylase activity Catalysis of the reaction: echinenone + a reduced electron acceptor + oxygen = 3-hydroxyechinenone + an oxidized electron acceptor + H2O. GO:0052607 7-hydroxy-chlorophyllide a oxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052607 MetaCyc:RXN-7677|RHEA:22136|KEGG_REACTION:R08204 7-hydroxychlorophyllide-a oxygenase activity|CAO activity|7-hydroxychlorophyllide a:oxygen 7-oxidoreductase activity|chlorophyll b synthetase activity|chlorophyll-b synthase activity Catalysis of the reaction: 7-hydroxychlorophyllide a + NADPH + O2 + H+ = chlorophyllide b + NADP+ + 2 H2O. GO:0052606 chlorophyllide a oxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052606 MetaCyc:RXN-7676|RHEA:22676|KEGG_REACTION:R08203 chlorophyllide-a oxygenase activity|CAO activity|chlorophyllide a:oxygen 7-oxidoreductase activity|chlorophyll a oxygenase activity Catalysis of the reaction: chlorophyllide a + NADPH + O2 + 2 H+ = 7-hydroxychlorophyllide a + NADP+ + H2O. CHEBI:136969 4-hydroxyestrone 3-O-(beta-D-glucuronide)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136969 CHEBI:88112 3-oxochola-4,6-dien-24-oic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88112 CHEBI:88115 N(2)-L-glutamino(1-) group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88115 CHEBI:88117 2-ethylhexyl sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88117 CHEBI:88119 dTDP-2,3-dehydro-2,6-dideoxy-4-keto-alpha-D-glucose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88119 CHEBI:88118 2,3-epoxy-2,3-dihydrobenzoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88118 CHEBI:136967 2-hydroxyestrone 3-O-(beta-D-glucuronide)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136967 CHEBI:136966 3beta-hydroxysteroid-4alpha-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136966 CHEBI:136965 lithocholate 3-O-(beta-D-glucuronide)(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136965 CHEBI:78785 O-(S-2,3-saturated acylpantetheine-4'-phosphoryl)serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78785 CHEBI:78784 O-[S-(2E)-2-enoylpantetheine-4'-phosphoryl]-L-serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78784 CHEBI:78783 O-(S-oleoylpantetheine-4'-phosphoryl)serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78783 CHEBI:39174 2-chloropyridine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_39174 CHEBI:136960 ditrans,polycis-polyprenyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136960 GO:0003689 DNA clamp loader activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003689 Reactome:R-HSA-176264|Reactome:R-HSA-174439 DNA clamp loading ATPase activity|PCNA loading complex activity|PCNA loading activity Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the opening of the ring structure of the PCNA complex, or any of the related sliding clamp complexes, and their closing around the DNA duplex. GO:0052612 adonirubin 3-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052612 EC:1.14.99.-|MetaCyc:RXN-8187 carotene beta-ring hydroxylase activity|beta-ring carotenoid 3-hydroxylase activity|beta-carotene hydroxylase activity Catalysis of the reaction: adonirubin + a reduced electron acceptor + oxygen = 3S,3'S-astaxanthin + an oxidized electron acceptor + H2O. GO:0003688 DNA replication origin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003688 ARS binding Interacting selectively and non-covalently with the DNA replication origin, a unique DNA sequence of a replicon at which DNA replication is initiated and proceeds bidirectionally or unidirectionally. GO:0052611 beta-carotene 3-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052611 MetaCyc:RXN-8025|EC:1.14.99.-|RHEA:30323 carotene beta-ring hydroxylase activity|beta-carotene 3-hydroxylase activity|beta-carotene hydroxylase activity Catalysis of the reaction: beta-carotene + a reduced electron acceptor + oxygen = beta-cryptoxanthin + an oxidized electron acceptor + H2O. GO:0052610 beta-cryptoxanthin hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052610 RHEA:30327|MetaCyc:RXN-8026|EC:1.14.99.- carotene beta-ring hydroxylase activity|beta-ring carotenoid 3-hydroxylase activity|beta-carotene hydroxylase activity Catalysis of the reaction: beta-cryptoxanthin + a reduced electron acceptor + oxygen = zeaxanthin + an oxidized electron acceptor + H2O. GO:0052616 ent-kaur-16-en-19-ol oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052616 EC:1.14.14.86|MetaCyc:RXN-5242|RHEA:21304 Catalysis of the reaction: H+ + NADPH + ent-kaur-16-en-19-ol + oxygen = 2 H2O + NADP+ + ent-kaur-16-en-19-al. GO:0003685 obsolete DNA repair protein biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003685 DNA repair protein OBSOLETE. (Was not defined before being made obsolete). GO:0052615 ent-kaurene oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052615 EC:1.14.14.86|RHEA:32323|MetaCyc:1.14.13.78-RXN Catalysis of the reaction: H+ + NADPH + ent-kaur-16-ene + oxygen = H2O + NADP+ + ent-kaur-16-en-19-ol. GO:0003684 damaged DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003684 DNA repair enzyme|DNA repair protein Interacting selectively and non-covalently with damaged DNA. GO:0003687 obsolete DNA replication factor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003687 DNA replication factor OBSOLETE. (Was not defined before being made obsolete). GO:0052614 uracil oxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052614 MetaCyc:RXN0-6444|RHEA:31587 pyrimidine oxygenase activity Catalysis of the reaction: uracil + NADH + O2 + H+ = ureidoacrylate peracid + NAD+. Ureidoacrylate peracid is spontaneously reduced by NADH to form ureidoacrylate. CHEBI:39192 dithiolanes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39192 GO:0003686 obsolete DNA repair enzyme biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003686 DNA repair enzyme OBSOLETE. (Was not defined before being made obsolete). GO:0052613 canthaxanthin 3-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052613 EC:1.14.99.-|MetaCyc:RXN-8186 carotene beta-ring hydroxylase activity|beta-ring carotenoid 3-hydroxylase activity|beta-carotene hydroxylase activity Catalysis of the reaction: canthaxanthin + a reduced electron acceptor + oxygen = adonirubin + an oxidized electron acceptor + H2O. GO:0003681 bent DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003681 Interacting selectively and non-covalently with DNA in a bent conformation. GO:0003680 minor groove of adenine-thymine-rich DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003680 AT binding|AT-rich DNA binding|AT DNA binding Interacting selectively and non-covalently with the structure formed by the minor groove of adenine-thymine-rich DNA regions. Examples of proteins having this function are AT-rich interaction domain (ARID)-containing proteins. GO:0052619 coenzyme F420-1:gamma-L-glutamate ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052619 RHEA:30523|EC:6.3.2.34|MetaCyc:RXN-8081 Catalysis of the reaction: GTP + L-glutamate + factor gamma-F420-1 = GDP + H+ + factor gamma-F420-2 + phosphate. GO:0052618 coenzyme F420-0:L-glutamate ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052618 RHEA:30555|EC:6.3.2.31|MetaCyc:RXN-8080 Catalysis of the reaction: GTP + L-glutamate + factor F420-0 = GDP + H+ + factor gamma-F420-1 + phosphate. GO:0003683 obsolete lamin/chromatin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003683 lamin/chromatin binding OBSOLETE. (Was not defined before being made obsolete). CHEBI:88102 3beta,7alpha-dihydroxy-5beta-cholan-24-oic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88102 GO:0003682 chromatin binding biolink:MolecularActivity go-plus goslim_pir|goslim_plant|goslim_drosophila|goslim_chembl|goslim_yeast http://purl.obolibrary.org/obo/GO_0003682 microtubule/chromatin interaction|lamin/chromatin binding|nuclear membrane vesicle binding to chromatin Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase. GO:0052617 ent-kaur-16-en-19-al oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052617 RHEA:10928|EC:1.14.14.86|MetaCyc:RXN-7580 Catalysis of the reaction: NADPH + ent-kaur-16-en-19-al + oxygen = H2O + NADP+ + ent-kaurenoate. CHEBI:64152 cysteine protease inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64152 CHEBI:88104 12alpha-hydroxy-3-oxo-5beta-cholan-24-oic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88104 CHEBI:88105 3beta,7alpha,12alpha-trihydroxy-5beta-cholan-24-oic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88105 CHEBI:136975 4-methoxy-17beta-estradiol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136975 CHEBI:88108 7alpha,12alpha-dihydroxy-3-oxo-5beta-cholan-24-oic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88108 CHEBI:136974 2-methoxy-17beta-estradiol 3-O-(beta-D-glucuronide)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136974 CHEBI:88107 geranyl phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88107 CHEBI:136973 4-methoxyestrone 3-O-(beta-D-glucuronide)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136973 CHEBI:136972 4-methoxyestrone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136972 CHEBI:88109 7alpha-hydroxy-3-oxochol-4-en-24-oic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88109 CHEBI:136979 isowyosine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136979 CHEBI:136978 5'-(N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-purine-ribonucleotide)-(2'-O-methyl-ribonucleotide)(3-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136978 CHEBI:136977 5'-(N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-purine-ribonucleotide)-(ribonucleotide)(3-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136977 CHEBI:136976 4-methoxy-17beta-estradiol 3-O-(beta-D-glucuronide)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136976 CHEBI:78796 nonadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78796 CHEBI:78795 pentadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78795 CHEBI:136971 2-methoxyestrone 3-O-(beta-D-glucuronide)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136971 CHEBI:136970 4-hydroxyestrone 4-O-(beta-D-glucuronide)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136970 CHEBI:78798 O-[S-(3Z)-decenoylpantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78798 GO:0052623 ADP dimethylallyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052623 EC:2.5.1.-|KEGG_REACTION:R08051|MetaCyc:RXN-4305 ADP isopentenyltransferase activity|2-isopentenyl-diphosphate:ADP 2-isopentenyltransferase activity|2-isopentenyl-diphosphate:ADP delta2-isopentenyltransferase activity|dimethylallyl-diphosphate:ADP dimethylallyltransferase activity Catalysis of the reaction: delta2-isopentenyl diphosphate + ADP = diphosphate + N6-(delta(2)-isopentenyl)adenosine 5'-diphosphate. GO:0052622 ATP dimethylallyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052622 KEGG_REACTION:R08052|EC:2.5.1.-|MetaCyc:RXN-4303 dimethylallyl-diphosphate:ATP dimethylallyltransferase activity|ATP isopentenyltransferase activity|2-isopentenyl-diphosphate:ATP 2-isopentenyltransferase activity|2-isopentenyl-diphosphate:ATP delta2-isopentenyltransferase activity Catalysis of the reaction: delta(2)-isopentenyl diphosphate + ATP = diphosphate + N6-(delta(2)-isopentenyl)adenosine 5'-triphosphate. GO:0052621 diguanylate cyclase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052621 RHEA:24898|EC:2.7.7.65|KEGG_REACTION:R08057|MetaCyc:RXN0-5359 GTP:GTP guanylyltransferase activity Catalysis of the reaction: 2 GTP = cyclic di-3',5'-guanylate + 2 diphosphate + 2 H(+). GO:0052620 thymine dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052620 RHEA:13469|MetaCyc:RXN-8646|EC:1.17.99.4 Catalysis of the reaction: H2O + thymine + acceptor = 5-methyl-barbiturate + donor-H2. CHEBI:39162 (R)-nicotine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39162 GO:0052627 vanillate amino acid synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052627 Catalysis of the reaction: vanillate + ATP + amino acid = vanillate amino acid conjugate + AMP + diphosphate. GO:0052626 benzoate amino acid synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052626 benzoyl amino acid synthetase activity Catalysis of the reaction: benzoate + ATP + amino acid = benzoyl amino acid conjugate + AMP + diphosphate. CHEBI:64161 asperthecin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64161 CHEBI:39161 1,1,1-trichloro-2,2-diphenylethane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_39161 GO:0052625 4-aminobenzoate amino acid synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052625 p-aminobenzoyl amino acid synthetase activity|p-aminobenzoate amino acid synthetase activity|4-aminobenzoyl amino acid synthetase activity|pABA amino acid synthetase activity Catalysis of the reaction: 4-aminobenzoate + ATP + amino acid = 4-aminobenzoyl amino acid conjugate + AMP + diphosphate. GO:0052624 2-phytyl-1,4-naphthoquinone methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052624 KEGG_REACTION:R06859|MetaCyc:RXN-6723|MetaCyc:RXN-7569 SA methyltransferase activity|S-adenosyl-L-methionine:salicylate carboxyl methyltransferase activity|salicylic acid methyltransferase activity|S-adenosyl-L-methionine:2-phytyl-1,4-naphthoquinone methyltransferase activity|S-adenosyl-L-methionine:demethylphylloquinone methyltransferase activity|demethylphylloquinone methyltransferase activity|salicylate methyltransferase activity Catalysis of the reaction: demethylphylloquinone + S-adenosyl-L-methionine = phylloquinone + S-adenosyl-L-homocysteine + H+. CHEBI:88133 D-ribitol 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88133 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052629 Reactome:R-HSA-6809320|Reactome:R-HSA-1676203|EC:3.1.3.95|RHEA:39019|Reactome:R-HSA-1676065|Reactome:R-HSA-1676105|MetaCyc:RXN-10958|Reactome:R-HSA-6809944|Reactome:R-HSA-6809778 Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H2O = a 1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphate + 2 H+. CHEBI:88135 N-acetylmethionine sulfone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88135 GO:0052628 4-hydroxybenzoate amino acid synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052628 4HBA amino acid synthetase activity|4-hydroxybenzoyl amino acid synthetase activity|p-hydroxybenzoyl amino acid synthetase activity|p-hydroxybenzoate amino acid synthetase activity Catalysis of the reaction: 4-hydroxybenzoate + ATP + amino acid = 4-hydroxybenzoyl amino acid conjugate + AMP + diphosphate. CHEBI:88137 2-hydro-beta-NADP(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88137 CHEBI:88136 N-acetyl-L-methionine sulfoximine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88136 CHEBI:88139 6-hydro-beta-NADP(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88139 CHEBI:88138 2-hydro-beta-NAD(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88138 CHEBI:39155 chlorocycloalkane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39155 CHEBI:39154 chlorocyclohexane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39154 CHEBI:39153 5-oxopentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39153 CHEBI:39159 (S)-trichostatic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39159 CHEBI:39158 (R)-trichostatic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39158 CHEBI:39157 trichostatic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39157 GO:0052634 C-19 gibberellin 2-beta-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052634 EC:1.14.11.13 C-19 gibberellin 2beta-dioxygenase activity|C-19 gibberellin 2beta-hydroxylase activity|C-19 GA 2-oxidase activity|(C-19 gibberellin-1),2-oxoglutarate:oxygen oxidoreductase (2beta-hydroxylating)|C-19 gibberellin 2-oxidase activity|C-19 gibberellin 2-beta-hydroxylase activity|C(19) gibberellin 2-oxidase activity Catalysis of the reaction: a C-19 gibberellin + 2-oxoglutarate + O2 = a C-19 2-beta-hydroxygibberellin + succinate + CO2. C-19 gibberellin refers to a gibberellin with nineteen carbons. GO:0052633 isocitrate hydro-lyase (cis-aconitate-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052633 KEGG_REACTION:R01900|MetaCyc:ACONITATEHYDR-RXN|RHEA:22144 citrate hydro-lyase activity|citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|cis-aconitase activity|aconitate hydratase activity|citrate(isocitrate) hydro-lyase activity Catalysis of the reaction: cis-aconitate + H2O = isocitrate. GO:0052632 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0052632 GO:0052631 sphingolipid delta-8 desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052631 MetaCyc:RXN-7798|RHEA:46268 Catalysis of the formation of a double bond between C8 and C9 of the long chain base of a sphingolipid. For example, sphinganine (d18:0) = 8-sphingenine (d18:1delta8); phytosphinganine (t18:0) = 8-phytosphingenine (t18:1delta8); and 4-sphingenine (18:1delta4) = 4,8-sphingadienine (d18:2delta4,8). GO:0052638 indole-3-butyrate beta-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052638 MetaCyc:RXN-11655|RHEA:62708 UDP-glucose:indol-3-ylbutyrate glucosyltransferase activity|IBA-glucose synthase activity|IBA-Glc synthetase activity|IBAGlu synthase activity|UDPglucose:indole-3-butyrate beta-D-glucosyltransferase activity|UDP-glucose:indol-3-ylbutyrate glucosyl-transferase activity|indol-3-ylbutyrylglucose synthase activity|uridine diphosphoglucose-indolebutyrate glucosyltransferase activity|UDP-glucose:(indol-3-yl)butyrate beta-D-glucosyltransferase activity|indole-3-butyric acid glucosyltransferase activity|UDPG-indol-3-ylbutyryl glucosyl transferase activity Catalysis of the reaction: indole-3-butyrate + UDP-D-glucose = indole-3-butyryl-beta-1-D-glucose + UDP. CHEBI:39173 chloropyridine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39173 NCBITaxon:3398 Magnoliopsida organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_3398 Magnoliophyta|Angiospermae|flowering plants|flowering plants|angiosperms GO:0052637 delta 3-trans-hexadecenoic acid phosphatidylglycerol desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052637 Catalysis of the reaction: 1-18:3-3-16:0-phosphatidylglycerol = 1-18:3-3-trans-16:1-phosphatidylglycerol + 2 H+. This reaction is the formation of a trans double bond between carbon 3 and carbon 4 (counting from the carboxyl end) of palmitic acid, which is specifically esterified to the sn-2 glyceryl carbon of phosphatidylglycerol. CHEBI:39172 monochloropyridine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39172 GO:0052636 arabinosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052636 arabinosyl transferase activity Catalysis of the transfer of an arabinosyl group from one compound (donor) to another (acceptor). GO:0052635 C-20 gibberellin 2-beta-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052635 C-20 gibberellin 2beta-hydroxylase activity|C-20 gibberellin 2-beta-hydroxylase activity|C(20) gibberellin 2-oxidase activity|C-20 gibberellin 2-oxidase activity|C-20 gibberellin 2beta-dioxygenase activity|C-20 GA 2-oxidase activity|(C-20 gibberellin-1),2-oxoglutarate:oxygen oxidoreductase (2beta-hydroxylating) Catalysis of the reaction: a C-20 gibberellin + 2-oxoglutarate + O2 = a C-20 2-beta-hydroxygibberellin + succinate + CO2. C-20 gibberellin refers to a gibberellin with twenty carbons. GO:0052639 salicylic acid glucosyltransferase (ester-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052639 RHEA:62316|MetaCyc:RXN-11659 UDP:glucose:SA glucosyltransferase (ester-forming) activity|UDP:glucose:2-hydroxybenzoic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase activity|UDP:glucose:salicylic acid glucosyltransferase (ester-forming) activity|UDP:glucose:salicylate glucosyltransferase (ester-forming) activity Catalysis of the reaction: salicylic acid + UDP-glucose = salicylic acid glucose ester + UDP. CHEBI:88123 (R)-12-hydroxysqualene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88123 CHEBI:64178 (2S)-2-amino-3-oxo-4-(phosphonatooxy)butanoate(3-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64178 CHEBI:39166 tetramine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39166 GO:0052630 UDP-N-acetylgalactosamine diphosphorylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052630 RHEA:34363|EC:2.7.7.83 uridine diphosphoacetylgalactosamine pyrophosphorylase activity|UTP:2-acetamido-2-deoxy-alpha-D-galactose-1-phosphate uridylyltransferase activity|N-acetylgalactosamine 1-phosphate uridylyltransferase|UTP:N-acetyl-alpha-D-galactosamine-1-phosphate uridylyltransferase activity|uridine diphosphoacetylgalactosamine phosphorylase activity|N-acetylgalactosamine-1-phosphate uridyltransferase activity|UDP-acetylgalactosamine pyrophosphorylase activity|uridine diphosphate-N-acetylgalactosamine pyrophosphorylase activity|UDP-N-acetylgalactosamine pyrophosphorylase activity|UDP-GalNAc pyrophosphorylase activity Catalysis of the reaction: UTP + N-acetyl-alpha-D-galactosamine 1-phosphate = diphosphate + UDP-N-acetyl-D-galactosamine. GO:0052645 F420-0 metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052645 coenzyme F420-0 metabolic process|coenzyme F420-0 metabolism|F420-0 metabolism|F(420)-0 metabolic process The chemical reactions and pathways involving F420-0 (5-O-{[(1S)-1-carboxyethoxy](hydroxy)phosphoryl}-1-deoxy-1-(8-hydroxy-2,4-dioxo-2H-pyrimido[4,5-b]quinolin-10(4H)-yl)-D-ribitol), the fragment of coenzyme F420 remaining after formal hydrolytic removal of all of the glutamate residues. CHEBI:64180 2-decaprenyl-6-methoxyhydroquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64180 GO:0052644 chlorophyllide a metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052644 chlorophyllide a metabolism The chemical reactions and pathways involving chlorophyllide a, a chlorophyll lacking the terpenoid side chain, which is the functional parent of chlorophyll a. GO:0052643 chlorophyllide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052643 chlorophyllide metabolism The chemical reactions and pathways involving chlorophyllides, any chlorophyll lacking the terpenoid side chain such as phytyl or farnesyl. GO:0052642 lysophosphatidic acid phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052642 Reactome:R-HSA-8878654 LPA phosphatase activity|lysophosphatidate phosphatase activity Catalysis of the reaction: lysophosphatidic acid + H2O = phosphate + monoacylglycerol. GO:0052649 coenzyme gamma-F420-2 metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052649 coenzyme F420 metabolic process|F420-2 metabolism|F420-2 metabolic process|coenzyme gamma-F420-2 metabolism|coenzyme F420 metabolism The chemical reactions and pathways involving coenzyme gamma-F420-2 (F420-2; coenzyme F420; N-{N-[O-(7,8-didemethyl-8-hydroxy-5-deazariboflavin phospho)-(S)-lactyl]-gamma-L-glutamyl}-L-glutamate), the amide obtained by formal condensation of the carboxylic acid group of F420-0 with the amino group of L-gamma-glutamyl-L-glutamic acid. GO:0052648 ribitol phosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052648 ribitol phosphate metabolism The chemical reactions and pathways involving ribitol phosphates, any phosphorylated form of ribitol, the pentitol derived formally by reduction of the -CHO group of either D- or L-ribose. CHEBI:64183 ubiquinol-10 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64183 GO:0052647 pentitol phosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052647 pentitol phosphate metabolism The chemical reactions and pathways involving pentitol phosphates, any phosphorylated alditol with a chain of five carbon atoms in the molecule. CHEBI:64182 3-demethylubiquinol-10 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64182 CHEBI:88153 tripropionin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88153 GO:0052646 alditol phosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052646 alditol phosphate metabolism The chemical reactions and pathways involving alditol phosphates, any phosphorylated polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group. CHEBI:64181 2-decaprenyl-6-methoxy-3-methylhydroquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64181 CHEBI:88152 2-O-[alpha-D-mannosyl-(1->2)-alpha-D-glucosyl]-D-glyceric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88152 CHEBI:88155 dipropionin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88155 CHEBI:88154 alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88154 CHEBI:88157 cis-3-hydroxy-D-proline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88157 CHEBI:64186 (2S)-2-amino-3-oxo-4-(phosphonooxy)butanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64186 CHEBI:88156 diacetin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88156 CHEBI:88159 3-hydroxy-O,5-dimethyl-L-tyrosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88159 CHEBI:88158 1,4-naphthoquinone-2-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88158 GO:0052641 benzoic acid glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052641 MetaCyc:RXN-11660 UDP:glucose:BA glucosyltransferase activity|UDP:glucose:benzoic acid glucosyltransferase activity|benzoate glucosyltransferase activity|UDP:glucose:benzoate glucosyltransferase activity Catalysis of the reaction: benzoic acid + UDP-glucose = benzoic acid glucose ester + UDP. GO:0052640 salicylic acid glucosyltransferase (glucoside-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052640 MetaCyc:RXN-11658|RHEA:62312 UDP:glucose:salicylate glucosyltransferase (glucoside-forming) activity|UDP:glucose:SA glucosyltransferase (glucoside-forming) activity|UDP:glucose:2-hydroxybenzoic acid glucosyltransferase (glucoside-forming) activity|salicylic acid glucosyltransferase activity|UDP:glucose:salicylic acid glucosyltransferase (glucoside-forming) activity Catalysis of the reaction: salicylic acid + UDP-glucose = salicylic acid 2-O-glucoside + UDP. GO:0052656 L-isoleucine transaminase activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0052656 MetaCyc:BRANCHED-CHAINAMINOTRANSFERILEU-RXN|RHEA:24801|EC:2.6.1.42|KEGG_REACTION:R02199 L-isoleucine aminotransferase activity Catalysis of the reaction: 2-oxoglutarate + L-isoleucine = (S)-3-methyl-2-oxopentanoic acid + L-glutamic acid. GO:0052655 L-valine transaminase activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0052655 MetaCyc:BRANCHED-CHAINAMINOTRANSFERVAL-RXN|RHEA:24813|KEGG_REACTION:R01214|EC:2.6.1.42 L-valine aminotransferase activity Catalysis of the reaction: 2-oxoglutarate + L-valine = 3-methyl-2-oxobutanoic acid + L-glutamatic acid. GO:0052654 L-leucine transaminase activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0052654 MetaCyc:BRANCHED-CHAINAMINOTRANSFERLEU-RXN|EC:2.6.1.42|KEGG_REACTION:R01090 L-leucine aminotransferase activity Catalysis of the reaction: 2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamatic acid. GO:0052653 3',5'-cyclic diguanylic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052653 3',5'-cyclic diguanylic acid metabolism|cyclic diguanylate metabolic process|cyclic diguanylate metabolism|cdiGMP metabolism|cdiGMP metabolic process The chemical reactions and pathways involving 3',5'-cyclic diguanylic acid, a cyclic purine dinucleotide in which the base groups are guanine. CHEBI:88140 6-hydro-beta-NAD(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88140 GO:1904409 regulation of secretory granule organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904409 regulation of secretory granule organisation|regulation of secretory granule organization and biogenesis Any process that modulates the frequency, rate or extent of secretory granule organization. GO:0052659 inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052659 MetaCyc:RXN-8730|EC:3.1.3.56|KEGG_REACTION:R03430|Reactome:R-HSA-1855218|RHEA:11392|Reactome:R-HSA-1855213 inositol polyphosphate-5-phosphatase activity|Ins(1,3,4,5)P4 5-phosphatase activity|type II inositol polyphosphate 5-phosphatase activity|5PTase activity|Ins(1,3,4,5)P(4) 5-phosphatase activity|type I inositol-polyphosphate phosphatase activity|D-myo-inositol (1,3,4,5)-polyphosphate 5-phosphatase activity Catalysis of the reaction: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate. CHEBI:39150 4-oxopentanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_39150 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052658 Reactome:R-HSA-1855222|EC:3.1.3.56|KEGG_REACTION:R03394|RHEA:19797|Reactome:R-HSA-1855174|MetaCyc:3.1.3.56-RXN myo-inositol-1,4,5-trisphosphate 5-phosphatase activity|inositol 1,4,5-trisphosphate phosphatase activity|D-myo-inositol 1,4,5-triphosphate 5-phosphatase activity|L-myo-inositol 1,4,5-trisphosphate-monoesterase activity|inositol triphosphate 5-phosphomonoesterase activity|inositol polyphosphate-5-phosphatase activity|type II inositol polyphosphate 5-phosphatase activity|InsP(3) 5-phosphatase activity|Ins(1,4,5)P3 5-phosphatase activity|5PTase activity|inositol phosphate 5-phosphomonoesterase activity|type I inositol-polyphosphate phosphatase activity|1D-myo-inositol-1,4,5-trisphosphate 5-phosphohydrolase activity|D-myo-inositol 1,4,5-trisphosphate 5-phosphatase activity|D-myo-inositol(1,4,5)-trisphosphate 5-phosphatase activity|inosine triphosphatase activity|InsP3 5-phosphatase activity|inositol trisphosphate phosphomonoesterase activity Catalysis of the reaction: 1D-myo-inositol 1,4,5-trisphosphate + H2O = 1D-myo-inositol 1,4-bisphosphate + phosphate. GO:1904408 melatonin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1904408 Interacting selectively and non-covalently with melatonin. GO:1904407 positive regulation of nitric oxide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904407 up-regulation of nitric oxide metabolism|up regulation of nitric oxide metabolic process|upregulation of nitric oxide metabolism|upregulation of nitric oxide metabolic process|up regulation of nitric oxide metabolism|activation of nitric oxide metabolic process|activation of nitric oxide metabolism|up-regulation of nitric oxide metabolic process|positive regulation of nitric oxide metabolism Any process that activates or increases the frequency, rate or extent of nitric oxide metabolic process. GO:0052657 guanine phosphoribosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052657 KEGG_REACTION:R01229|RHEA:25424|EC:2.4.2.8|MetaCyc:GUANPRIBOSYLTRAN-RXN hypoxanthine-guanine phosphoribosyltransferase activity|6-mercaptopurine phosphoribosyltransferase activity|purine-6-thiol phosphoribosyltransferase activity|guanosine phosphoribosyltransferase activity|Transphosphoribosidase activity|GPRT|guanosine 5'-phosphate pyrophosphorylase activity|guanine-hypoxanthine phosphoribosyltransferase activity|guanylate pyrophosphorylase activity|guanylic pyrophosphorylase activity|GMP pyrophosphorylase activity|6-hydroxypurine phosphoribosyltransferase activity Catalysis of the reaction: GMP + diphosphate = guanine + 5-phospho-alpha-D-ribose 1-diphosphate. CHEBI:88141 2''-O-glutaryl-ADP-D-ribose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88141 GO:1904406 negative regulation of nitric oxide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904406 down-regulation of nitric oxide metabolic process|inhibition of nitric oxide metabolism|downregulation of nitric oxide metabolic process|down regulation of nitric oxide metabolic process|inhibition of nitric oxide metabolic process|down regulation of nitric oxide metabolism|downregulation of nitric oxide metabolism|negative regulation of nitric oxide metabolism|down-regulation of nitric oxide metabolism Any process that stops, prevents or reduces the frequency, rate or extent of nitric oxide metabolic process. GO:1904405 cellular response to formaldehyde biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904405 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a formaldehyde stimulus. CHEBI:88143 (3,4-dimethoxyphenyl)methyloxidanyl biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88143 GO:1904404 response to formaldehyde biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904404 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a formaldehyde stimulus. CHEBI:136937 4-hydroxy-17beta-estradiol 4-O-(beta-D-glucuronide)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136937 CHEBI:88146 2''-O-malonyl-ADP-D-ribose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88146 CHEBI:136936 4-hydroxy-17beta-estradiol 3-O-(beta-D-glucuronide)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136936 GO:1904403 cellular response to nocodazole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904403 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nocodazole stimulus. CHEBI:88145 2''-O-succinyl-ADP-D-ribose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88145 CHEBI:88148 2,3-saturated fatty acyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88148 GO:1904402 response to nocodazole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904402 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nocodazole stimulus. GO:1904401 cellular response to Thyroid stimulating hormone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904401 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroid stimulating hormone stimulus. CHEBI:88147 2,5-dihydroxybenzoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88147 GO:1904400 response to Thyroid stimulating hormone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904400 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroid stimulating hormone stimulus. CHEBI:88149 (S)-4-hydroxy-1-pyrroline-2-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88149 CHEBI:136931 2-hydroxy-17beta-estradiol 3-O-(beta-D-glucuronide)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136931 CHEBI:136933 2-hydroxy-17beta-estradiol 2-O-(beta-D-glucuronide)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136933 CHEBI:39144 Lewis base biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39144 CHEBI:39143 Lewis acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39143 CHEBI:39142 Bronsted base biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39142 CHEBI:39141 Bronsted acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39141 GO:0052652 cyclic purine nucleotide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052652 cyclic purine nucleotide metabolism The chemical reactions and pathways involving a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue and the base is a purine. GO:0052651 monoacylglycerol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052651 monoacylglycerol degradation|monoacylglycerol breakdown|monoacylglycerol catabolism The chemical reactions and pathways resulting in the breakdown of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified. GO:0052650 NADP-retinol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052650 Reactome:R-HSA-2464822|Reactome:R-HSA-5615668|Reactome:R-HSA-5623643|Reactome:R-HSA-2466861|KEGG_REACTION:R08379|Reactome:R-HSA-2471670|RHEA:25033|Reactome:R-HSA-2464803|Reactome:R-HSA-2465940|Reactome:R-HSA-74872|Reactome:R-HSA-5419165|EC:1.1.1.300|MetaCyc:RXN-10841|Reactome:R-HSA-2465921 NADP(H)-dependent retinol dehydrogenase/reductase activity|retinol dehydrogenase [NADP+] activity|all-trans-retinol dehydrogenase activity|all-trans retinal reductase activity|retinol:NADP+ oxidoreductase activity Catalysis of the reaction: all-trans-retinol + NADP+ = all-trans-retinal + NADPH + H+. CHEBI:39146 trichostatin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39146 GO:0052667 phosphomethylethanolamine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052667 RHEA:25322|MetaCyc:RXN-5642|KEGG_REACTION:R06868 N-methylethanolamine phosphate N-methyltransferase activity|S-adenosyl-L-methionine:methylethanolamine phosphate N-methyltransferase activity Catalysis of the reaction: N-methylethanolamine phosphate + S-adenosyl-L-methionine = N,N-dimethylethanolamine phosphate + S-adenosyl-L-homocysteine + H(+). GO:0052666 tRNA (cytosine-2'-O-)-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052666 Reactome:R-HSA-6788668|Reactome:R-HSA-6788684|Reactome:R-HSA-9024159|MetaCyc:RXN0-5143 tRNA cytosine 2'-methyltransferase activity|tRNA (cytosine 2')-methyltransferase activity|transfer ribonucleate cytosine 2'-methyltransferase activity|tRNA cytosine-2'-O-methyltransferase activity|S-adenosyl-L-methionine:tRNA cytosine-2'-O-methyltransferase activity|S-adenosyl-L-methionine:tRNA (cytosine-2'-O-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 2'-O-methylcytosine. GO:0052665 tRNA (uracil-2'-O-)-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052665 Reactome:R-HSA-6788707|MetaCyc:RXN0-5143 tRNA uracil 2'-methyltransferase activity|transfer ribonucleate uracil 2'-methyltransferase activity|tRNA (uracil 2')-methyltransferase activity|tRNA uracil-2'-O-methyltransferase activity|S-adenosyl-L-methionine:tRNA uracil-2'-O-methyltransferase activity|S-adenosyl-L-methionine:tRNA (uracil-2'-O-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 2'-O-methyluracil. CHEBI:15193 tartrate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15193 GO:0052664 nitroalkane oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052664 EC:1.7.3.1|MetaCyc:RXN-11045|KEGG_REACTION:R00799 nitroalkane reductase activity|NAO activity|nitroalkane:oxygen oxidoreductase activity Catalysis of the reaction: nitroalkane + H2O + O2 = an aldehyde or ketone + nitrite + H2O2. CHEBI:30789 4-sulfobenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30789 GO:1904419 negative regulation of telomeric loop formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904419 inhibition of telomeric loop formation|downregulation of t-loop formation|down regulation of t-loop formation|inhibition of t-loop formation|down regulation of t-loop biosynthesis|downregulation of t-loop biosynthesis|down-regulation of telomeric loop formation|down-regulation of t-loop biosynthesis|negative regulation of t-loop biosynthesis|down-regulation of t-loop formation|negative regulation of t-loop formation|inhibition of t-loop biosynthesis|downregulation of telomeric loop formation|down regulation of telomeric loop formation Any process that stops, prevents or reduces the frequency, rate or extent of telomeric loop formation. GO:0052669 CTP:2-trans,-6-trans-farnesol kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052669 EC:2.7.1.216|RHEA:51680|MetaCyc:RXN-11625 CTP:2-trans,-6-trans-farnesol phosphotransferase activity Catalysis of the reaction: 2-trans,-6-trans-farnesol + CTP = 2-trans,-6-trans-farnesyl monophosphate + CDP + H+. GO:0052668 farnesol kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052668 EC:2.7.1.216 farnesol phosphotransferase activity|trans,trans-farnesol kinase activity Catalysis of the reaction: farnesol + nucleoside triphosphate = farnesyl monophosphate + nucleoside diphosphate. GO:1904418 regulation of telomeric loop formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904418 regulation of t-loop formation|regulation of t-loop biosynthesis Any process that modulates the frequency, rate or extent of telomeric loop formation. GO:1904417 positive regulation of xenophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904417 upregulation of xenophagy|up regulation of xenophagy|activation of xenophagy|up-regulation of xenophagy Any process that activates or increases the frequency, rate or extent of xenophagy. CHEBI:136906 hyocholate 6-O-(beta-D-glucuronide)(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136906 CHEBI:136905 hyodeoxycholate 6-O-(beta-D-glucuronide)(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136905 GO:1904416 negative regulation of xenophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904416 down regulation of xenophagy|downregulation of xenophagy|down-regulation of xenophagy|inhibition of xenophagy Any process that stops, prevents or reduces the frequency, rate or extent of xenophagy. GO:1904415 regulation of xenophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904415 Any process that modulates the frequency, rate or extent of xenophagy. CHEBI:136904 hyocholic acid 24-O-(beta-D-glucuronide)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136904 GO:1904414 positive regulation of cardiac ventricle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904414 up-regulation of cardiac ventricle development|upregulation of cardiac ventricle development|up regulation of cardiac ventricle development|activation of cardiac ventricle development Any process that activates or increases the frequency, rate or extent of cardiac ventricle development. CHEBI:136903 hyodeoxycholic acid 24-O-(beta-D-glucuronide)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136903 GO:1904413 negative regulation of cardiac ventricle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904413 inhibition of cardiac ventricle development|down regulation of cardiac ventricle development|downregulation of cardiac ventricle development|down-regulation of cardiac ventricle development Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle development. CHEBI:29792 hydroperoxy group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29792 GO:1904412 regulation of cardiac ventricle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904412 Any process that modulates the frequency, rate or extent of cardiac ventricle development. UBERON:2005117 anterior lateral line primordium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_2005117 anterior lateral line primordia A migrating group of cells originating from an anterior lateral line placode. The primordium deposits neuromasts and interneuromasts between them during its migration. GO:1904411 positive regulation of secretory granule organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904411 upregulation of secretory granule organization and biogenesis|up-regulation of secretory granule organization|activation of secretory granule organization|positive regulation of secretory granule organisation|up regulation of secretory granule organisation|up regulation of secretory granule organization and biogenesis|positive regulation of secretory granule organization and biogenesis|up regulation of secretory granule organization|activation of secretory granule organization and biogenesis|upregulation of secretory granule organisation|up-regulation of secretory granule organization and biogenesis|upregulation of secretory granule organization|up-regulation of secretory granule organisation|activation of secretory granule organisation Any process that activates or increases the frequency, rate or extent of secretory granule organization. CHEBI:136908 (7R,8R)-7,8-dihydroxy-C2-C8-saturated long-chain fatty acyl pantetheine-4-phosphorylserine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136908 GO:1904410 negative regulation of secretory granule organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904410 down regulation of secretory granule organization and biogenesis|down-regulation of secretory granule organisation|negative regulation of secretory granule organisation|downregulation of secretory granule organization and biogenesis|down-regulation of secretory granule organization|downregulation of secretory granule organisation|down-regulation of secretory granule organization and biogenesis|negative regulation of secretory granule organization and biogenesis|down regulation of secretory granule organisation|inhibition of secretory granule organisation|downregulation of secretory granule organization|down regulation of secretory granule organization|inhibition of secretory granule organization|inhibition of secretory granule organization and biogenesis Any process that stops, prevents or reduces the frequency, rate or extent of secretory granule organization. CHEBI:29793 hydridodioxygen(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29793 CHEBI:136907 (7S)-7-hydroxy-C2-C8-saturated long-chain fatty acyl pantetheine-4-phosphorylserine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136907 GO:1904420 positive regulation of telomeric loop formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904420 up regulation of telomeric loop formation|up-regulation of t-loop biosynthesis|positive regulation of t-loop formation|up regulation of t-loop formation|upregulation of telomeric loop formation|upregulation of t-loop biosynthesis|upregulation of t-loop formation|up-regulation of telomeric loop formation|activation of telomeric loop formation|up regulation of t-loop biosynthesis|activation of t-loop biosynthesis|positive regulation of t-loop biosynthesis|up-regulation of t-loop formation|activation of t-loop formation Any process that activates or increases the frequency, rate or extent of telomeric loop formation. CHEBI:39116 pyrethroid ester insecticide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39116 CHEBI:136902 lithocholic acid 24-O-(beta-D-glucuronide)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136902 CHEBI:136901 deoxycholic acid 24-O-(beta-D-glucuronide)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136901 CHEBI:136900 cholic acid 24-O-(beta-D-glucuronide)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136900 CHEBI:30782 acetylenedicarboxylate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30782 GO:0052663 antheraxanthin epoxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052663 KEGG_REACTION:R07200|KEGG_REACTION:R06947|MetaCyc:RXN-7979|RHEA:14937|EC:1.14.13.90 antheraxanthin,NAD(P)H:oxygen oxidoreductase activity Catalysis of the reaction: antheraxanthin + NAD(P)H + H+ + O2 = all-trans-violaxanthin + NAD(P)+ + H2O. CHEBI:30781 butynedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30781 GO:0052662 zeaxanthin epoxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052662 RHEA:24084|KEGG_REACTION:R06946|KEGG_REACTION:R07199|MetaCyc:RXN-7978|EC:1.14.13.90 zeaxanthin,NAD(P)H:oxygen oxidoreductase activity|zea-epoxidase activity Catalysis of the reaction: zeaxanthin + NAD(P)H + H+ + O2 = antheraxanthin + NAD(P)+ + H2O. CHEBI:30780 maleate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30780 GO:0052661 S-lactaldehyde reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052661 MetaCyc:LACTALDREDUCT-RXN|RHEA:15933|KEGG_REACTION:R02258 L-lactaldehyde:propanediol oxidoreductase activity|(S)-propane-1,2-diol:NAD+ oxidoreductase activity Catalysis of the reaction: (S)-propane-1,2-diol + NAD+ = (S)-lactaldehyde + NADH + H+. GO:0052660 R-lactaldehyde reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052660 KEGG_REACTION:R03080|MetaCyc:RXN-8641|RHEA:23872 D-lactaldehyde:propanediol oxidoreductase activity|(R)-propane-1,2-diol:NAD+ oxidoreductase activity Catalysis of the reaction: (R)-propane-1,2-diol + NAD+ = (R)-lactaldehyde + NADH + H+. GO:0052678 levopimaradiene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052678 RHEA:25548|EC:4.2.3.32|KEGG_REACTION:R06302|MetaCyc:4.2.3.32-RXN ent-copalyl-diphosphate diphosphate-lyase [ent-abieta-8(14),12-diene-forming] activity Catalysis of the reaction: (+)-copalyl diphosphate = abieta-8(14),12-diene + diphosphate. GO:0052677 D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052677 MetaCyc:RXN-7971|RHEA:21276|KEGG_REACTION:R07143 D-arabinitol dehydrogenase 1 activity|D-arabinitol:NADP+ dehydrogenase activity|ARD1p|NADP+-dependent D-arabinitol dehydrogenase activity Catalysis of the reaction: D-arabinitol + NADP+ = D-xylulose + NADPH + H+. GO:0052676 3-methylbutanol:NAD oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052676 RHEA:18529|KEGG_REACTION:R05685 3-methylbutyraldehyde reductase (NAD) activity|3-methylbutanal reductase (NAD) activity|isoamyl alcohol oxidase (NAD) activity|3-methylbutanol:NAD+ oxidoreductase activity Catalysis of the reaction: 3-methylbutanol + NAD+ = 3-methylbutanal + NADH + H+. 3-methylbutanal is also known as isovaleraldehyde. GO:0052675 3-methylbutanol:NADP oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052675 RHEA:18525|KEGG_REACTION:R05686 3-methylbutanol:NADP+ oxidoreductase activity|isoamyl alcohol oxidase (NADP) activity|3-methylbutanal reductase (NADP) activity|3-methylbutyraldehyde reductase (NADP) activity Catalysis of the reaction: 3-methylbutanol + NADP+ = 3-methylbutanal + NADPH + H+. 3-methylbutanal is also known as isovaleraldehyde. CHEBI:88164 3-chloroalanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88164 GO:1904429 regulation of t-circle formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904429 regulation of telomeric circle formation Any process that modulates the frequency, rate or extent of t-circle formation. GO:0052679 terpentetriene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052679 MetaCyc:RXN-9455|RHEA:25617|EC:4.2.3.36 terpentedienyl-diphosphate diphosphate-lyase (terpentetriene-forming) activity Catalysis of the reaction: terpentedienyl diphosphate = diphosphate + terpentetriene. CHEBI:30797 (S)-malic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30797 GO:1904428 negative regulation of tubulin deacetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904428 down-regulation of tubulin deacetylation|inhibition of tubulin deacetylation|down regulation of tubulin deacetylation|downregulation of tubulin deacetylation Any process that stops, prevents or reduces the frequency, rate or extent of tubulin deacetylation. CHEBI:88166 (S)-2-methylbutanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88166 GO:1904427 positive regulation of calcium ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904427 up-regulation of calcium ion membrane transport|activation of calcium ion membrane transport|up-regulation of transmembrane calcium transport|upregulation of calcium ion transmembrane transport|positive regulation of calcium ion membrane transport|upregulation of transmembrane calcium transport|up regulation of calcium ion transmembrane transport|up regulation of calcium ion membrane transport|activation of calcium ion transmembrane transport|up regulation of transmembrane calcium transport|activation of transmembrane calcium transport|positive regulation of transmembrane calcium transport|upregulation of calcium ion membrane transport|up-regulation of calcium ion transmembrane transport Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transport. CHEBI:136916 5alpha-dihydrotestosterone 17-O-[beta-D-glucuronosyl-(1->2)-glucuronide](2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136916 GO:1904426 positive regulation of GTP binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904426 up regulation of GTP binding|activation of GTP binding|up-regulation of GTP binding|upregulation of GTP binding Any process that activates or increases the frequency, rate or extent of GTP binding. GO:1904425 negative regulation of GTP binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904425 down-regulation of GTP binding|inhibition of GTP binding|down regulation of GTP binding|downregulation of GTP binding Any process that stops, prevents or reduces the frequency, rate or extent of GTP binding. CHEBI:88167 N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88167 CHEBI:136914 5alpha-dihydrotestosterone 17-O-(beta-D-glucuronide)(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136914 GO:1904424 regulation of GTP binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904424 Any process that modulates the frequency, rate or extent of GTP binding. GO:1904423 dehydrodolichyl diphosphate synthase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_1904423 A protein complex which is capable of dehydrodolichyl diphosphate synthase activity. GO:1904422 cellular response to D-galactosamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904422 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactosamine stimulus. GO:1904421 response to D-galactosamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904421 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactosamine stimulus. GO:1904431 positive regulation of t-circle formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904431 positive regulation of telomeric circle formation|up regulation of telomeric circle formation|up regulation of t-circle formation|upregulation of telomeric circle formation|upregulation of t-circle formation|up-regulation of telomeric circle formation|activation of telomeric circle formation|up-regulation of t-circle formation|activation of t-circle formation Any process that activates or increases the frequency, rate or extent of t-circle formation. GO:1904430 negative regulation of t-circle formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904430 down-regulation of t-circle formation|downregulation of telomeric circle formation|down regulation of telomeric circle formation|inhibition of telomeric circle formation|downregulation of t-circle formation|down regulation of t-circle formation|inhibition of t-circle formation|down-regulation of telomeric circle formation|negative regulation of telomeric circle formation Any process that stops, prevents or reduces the frequency, rate or extent of t-circle formation. CHEBI:39128 magnesium ion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39128 CHEBI:39127 magnesium cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39127 CHEBI:136913 monoacyl-sn-glycero-3-phospholipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136913 CHEBI:136912 1,2-diacyl-sn-glycero-3-phospholipid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136912 CHEBI:136911 N-(4-ammoniobutylidene)-L-lysinium(2+) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136911 CHEBI:136910 O-[S-(7-oxoheptanoyl)pantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136910 GO:0052670 geraniol kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052670 geraniol phosphotransferase activity Catalysis of the reaction: geraniol + nucleoside triphosphate = geranyl monophosphate + nucleoside diphosphate. CHEBI:30796 (R)-malic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30796 CHEBI:15176 tRNA(Glx) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15176 CHEBI:30795 malonate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30795 CHEBI:30794 malonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30794 CHEBI:30793 2-chlorobenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30793 GO:0052674 ent-pimara-9(11),15-diene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052674 MetaCyc:RXN-9299|EC:4.2.3.31|RHEA:25544 ent-copalyl-diphosphate diphosphate-lyase [ent-pimara-9(11),15-diene-forming] activity|PMD synthase activity Catalysis of the reaction: ent-copalyl diphosphate = ent-pimara-9(11),15-diene + diphosphate. GO:0052673 prenol kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052673 prenyl alcohol kinase activity|prenyl alcohol phosphotransferase activity|prenol phosphotransferase activity Catalysis of the reaction: prenol + nucleoside triphosphate = prenyl phosphate + nucleoside diphosphate activity. CHEBI:15172 tRNA(Asx) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15172 GO:0052672 CTP:geranylgeraniol kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052672 EC:2.7.1.216|MetaCyc:RXN-11629 CTP:geranylgeraniol phosphotransferase activity Catalysis of the reaction: geranylgeraniol + CTP = all-trans-geranyl-geranyl monophosphate + CDP. CHEBI:39124 calcium ion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39124 CHEBI:39123 calcium cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39123 GO:0052671 geranylgeraniol kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052671 geranylgeraniol phosphotransferase activity Catalysis of the reaction: geranylgeraniol + nucleoside triphosphate = all-trans-geranyl-geranyl monophosphate + nucleoside diphosphate. CHEBI:78703 2-arachidonoyl-sn-glycero-3-phospho-L-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78703 CHEBI:78709 3-deoxy-D-threo-hex-2-ulosaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78709 CHEBI:78700 9-oxononanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78700 CHEBI:78715 1,4,5,6-tetrahydropyrimidines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78715 CHEBI:78718 UDP-alpha-D-glucosamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78718 CHEBI:78717 UDP-alpha-D-galactosamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78717 CHEBI:78712 tetrahydropyrimidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78712 CHEBI:78723 3'-(D-tyrosyl)adenylyl(1-) group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78723 CHEBI:78737 fructose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78737 CHEBI:78736 D-fructose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78736 CHEBI:78730 9(R)-HODE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78730 CHEBI:78734 tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78734 CHEBI:78732 9-HPETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78732 CHEBI:78731 9(R)-HPETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78731 PR:000016964 ubiquitin D biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000016964 UBD|FAT10|ubiquitin-like protein FAT10|diubiquitin A protein that is a translation product of the human UBD gene or a 1:1 ortholog thereof. PR:000016963 polyubiquitin-C biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000016963 UBC A polyubiquitin that is a translation product of the human UBC gene or a 1:1 ortholog thereof. CHEBI:64106 protein kinase agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64106 CHEBI:78741 oxidopamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78741 PR:000016954 ubiquitin-60S ribosomal protein L40 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000016954 UBA52|UBCEP2|CEP52|60S ribosomal protein L40 A protein that is a translation product of the human UBA52 gene or a 1:1 ortholog thereof. GO:0003699 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003699 CHEBI:78768 1-heptadecanoyl-2-arachidonoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78768 GO:0003696 satellite DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003696 Interacting selectively and non-covalently with satellite DNA, the many tandem repeats (identical or related) of a short basic repeating unit; many have a base composition or other property different from the genome average that allows them to be separated from the bulk (main band) genomic DNA. GO:0003695 obsolete random coil DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003695 random coil binding OBSOLETE. Interacting selectively and non-covalently with DNA in a random coil configuration. GO:0003698 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003698 GO:0003697 single-stranded DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003697 ssDNA binding Interacting selectively and non-covalently with single-stranded DNA. GO:0003692 left-handed Z-DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003692 Interacting selectively and non-covalently with DNA in the Z form, i.e. a left-handed helix in which the phosphate backbone zigzags. CHEBI:64121 P-factor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64121 GO:0003691 double-stranded telomeric DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003691 Interacting selectively and non-covalently with double-stranded telomere-associated DNA. GO:0003694 obsolete plasmid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003694 plasmid binding|plasmid-associated protein OBSOLETE. Interacting selectively with a plasmid, an extrachromosomal genetic element usually characterized as a covalently continuous double stranded DNA molecule found in bacteria and some other microorganisms. CHEBI:64120 M-factor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64120 GO:0003693 P-element binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003693 Interacting selectively and non-covalently with any P-element, a class of Drosophila transposon responsible for hybrid dysgenesis. GO:0003690 double-stranded DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003690 dsDNA binding Interacting selectively and non-covalently with double-stranded DNA. CHEBI:64124 phytosphingosine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64124 CHEBI:40196 N(6)-methyl-AMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_40196 CHEBI:136986 2-hydroxyhexacosanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136986 CHEBI:136985 S-prenyl-L-cysteine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136985 CHEBI:136984 EC 4.4.1.14 (1-aminocyclopropane-1-carboxylate synthase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136984 CHEBI:136983 (3beta,5alpha,17beta)-3-hydroxyandrostan-17-yl sulfate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136983 CHEBI:136989 N-[(5Z,11Z,14Z)-8,9-epoxyicosatrienoyl]ethanolamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136989 CHEBI:136988 N-[(8Z,11Z,14Z)-5,6-epoxyicosatrienoyl]ethanolamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136988 CHEBI:136987 N-[(2S)-2-amino-2-carboxyethyl]-L-glutamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136987 CHEBI:78762 1-oleoyl-sn-glycero-3-phospho-D-myo-inositol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78762 CHEBI:136982 5alpha-dihydrotestosterone sulfate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136982 CHEBI:78765 1-oleoyl-2-arachidonoyl-sn-glycero-3-phospho-1D-myo-inositol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78765 CHEBI:136980 2-hydroxy-3-O-methyl estrone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136980 CHEBI:78779 O-[S-(13Z)-3-oxooctadecenoylpantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78779 CHEBI:146306 partially-defined glycan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_146306 CHEBI:64133 EC 2.5.1.58 (protein farnesyltransferase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64133 CHEBI:64130 pyrazinoindole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64130 CHEBI:64136 4-hydroxy-3-all-trans-decaprenylbenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64136 CHEBI:136997 L-polyhomomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136997 CHEBI:136996 9-[(9Z)-octadecenoyloxy]octadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136996 CHEBI:136994 2-(glutathion-S-yl)-1,4-hydroquinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136994 CHEBI:136999 L-trihomomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136999 CHEBI:136998 L-dihomomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_136998 CHEBI:78772 alpha-ascarylopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78772 CHEBI:78771 ascarylopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78771 CHEBI:78778 O-[S-(11Z)-hexadecenoylpantetheine-4'-phosphoryl]serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78778 CHEBI:136992 N-(20-hydroxyarachidonoyl)ethanolamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136992 CHEBI:78776 O-(S-3-oxoacylpantetheine-4'-phosphoryl)-L-serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78776 CHEBI:136991 N-[(5Z,8Z,11Z)-14,15-epoxyicosatrienoyl]ethanolamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136991 CHEBI:136990 N-[(5Z,8Z,14Z)-11,12-epoxyicosatrienoyl]ethanolamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_136990 GO:1904399 heparan sulfate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1904399 Interacting selectively and non-covalently with heparan sulfate. CHEBI:29704 valiolone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29704 CHEBI:29706 10-deoxymethymycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29706 CHEBI:29701 tyrocidine A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29701 CHEBI:29700 tylactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29700 CHEBI:29703 validamycin A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29703 UBERON_CORE:channels_from channels_from biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/uberon/core#channels_from channels_from CHEBI:8504 prostanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_8504 GO:0003832 beta-alanyl-dopamine hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003832 N-beta-alanyl-dopamine hydrolase activity|NBAD hydrolase activity Catalysis of the reaction: N-beta-alanyl dopamine + H2O = dopamine + beta-alanine. CHEBI:88070 monooctanoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88070 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003831 Reactome:R-HSA-1912352|MetaCyc:2.4.1.38-RXN|Reactome:R-HSA-3656230|Reactome:R-HSA-2025723|EC:2.4.1.38|Reactome:R-HSA-975919|Reactome:R-HSA-2046265|Reactome:R-HSA-9035949|RHEA:22932|Reactome:R-HSA-9035950|Reactome:R-HSA-2046298|Reactome:R-HSA-4793956 UDPgalactose:N-acetyl-beta-D-glucosaminylglycopeptide beta-1,4-galactosyltransferase activity|uridine diphosphogalactose-glycoprotein galactosyltransferase activity|UDPgalactose-glycoprotein galactosyltransferase activity|GalT activity|thyroid galactosyltransferase activity|UDP-galactose--glycoprotein galactosyltransferase activity|glycoprotein 4-beta-galactosyltransferase activity|beta-N-acetyl-beta-(1,4)-galactosyltransferase activity|beta-N-acetyl-beta-1,4-galactosyltransferase activity|glycoprotein beta-galactosyltransferase activity|UDP-galactose:N-acetyl-beta-D-glucosaminylglycopeptide beta-1,4-galactosyltransferase activity|thyroid glycoprotein beta-galactosyltransferase|glycoprotein 4-beta-galactosyl-transferase activity Catalysis of the reaction: UDP-galactose + N-acetyl-beta-D-glucosaminylglycopeptide = UDP + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminylglycopeptide. GO:0003834 beta-carotene 15,15'-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003834 KEGG_REACTION:R00032|MetaCyc:BETA-CAROTENE-1515-DIOXYGENASE-RXN|Reactome:R-HSA-975635|EC:1.14.99.36|RHEA:32887 carotene 15,15'-dioxygenase activity|beta-carotene:oxygen 15,15'-oxidoreductase (bond-cleaving)|beta-carotene 15,15'-dioxygenase activity|carotene dioxygenase activity Catalysis of the reaction: beta-carotene + O(2) = 2 retinal. CHEBI:88072 (3S,5Z)-3-hydroxytetradec-5-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88072 CHEBI:30769 citric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30769 GO:0003833 beta-alanyl-dopamine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003833 NBAD transferase activity|N-beta-alanyl dopamine synthetase activity Catalysis of the synthesis of beta-alanyl-dopamine from the precursor dopamine (3,4-dihydroxyphenylethylamine). CHEBI:30768 propionic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30768 CHEBI:88071 monosialodiglycosylceramide(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88071 CHEBI:30767 (R)-tropic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30767 CHEBI:88073 alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88073 CHEBI:30766 (S)-tropic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30766 GO:0003830 beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003830 MetaCyc:2.4.1.144-RXN|EC:2.4.1.144|Reactome:R-HSA-975926|RHEA:15509 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase activity|N-acetylglucosaminyltransferase III activity|N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III activity|uridine diphosphoacetylglucosamine-glycopeptide beta-4-acetylglucosaminyltransferase III activity|GnTIII activity|UDP-N-acetyl-D-glucosamine:beta-D-mannosyl-glycoprotein 4-beta-N-acetyl-D-glucosaminyltransferase activity|uridine diphosphoacetylglucosamine-glycopeptide beta4-acetylglucosaminyltransferase III|beta-1,4-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-mannosyl-R = UDP + 4-(N-acetyl-beta-D-glucosaminyl)-beta-D-mannosyl-R. CHEBI:88076 monosialotriglycosylceramide(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88076 CHEBI:30765 tropic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30765 GO:1904319 negative regulation of smooth muscle contraction involved in micturition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904319 downregulation of smooth muscle contraction involved in urination|down-regulation of smooth muscle contraction involved in micturition|down-regulation of smooth muscle contraction involved in urination|negative regulation of smooth muscle contraction involved in urination|inhibition of smooth muscle contraction involved in micturition|inhibition of urinary bladder smooth muscle contraction involved in micturition|down regulation of urinary bladder smooth muscle contraction involved in micturition|inhibition of smooth muscle contraction involved in urination|downregulation of urinary bladder smooth muscle contraction involved in micturition|down regulation of smooth muscle contraction involved in micturition|downregulation of smooth muscle contraction involved in micturition|down regulation of smooth muscle contraction involved in urination|down-regulation of urinary bladder smooth muscle contraction involved in micturition|negative regulation of urinary bladder smooth muscle contraction involved in micturition Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle contraction involved in micturition. CHEBI:30764 3-hydroxybenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30764 CHEBI:88075 trisialodiglycosylceramide(3-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88075 GO:1904318 regulation of smooth muscle contraction involved in micturition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904318 regulation of urinary bladder smooth muscle contraction involved in micturition|regulation of smooth muscle contraction involved in urination Any process that modulates the frequency, rate or extent of smooth muscle contraction involved in micturition. CHEBI:88078 trisialotriglycosylceramide(3-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88078 CHEBI:88077 disialotriglycosylceramide(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88077 GO:1904317 cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904317 cellular response to PAF|cellular response to platelet-activating factor Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine stimulus. CHEBI:29773 aminooxidanide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29773 GO:1904316 response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904316 response to platelet-activating factor|response to PAF Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine stimulus. GO:0062130 adhesive extracellular matrix biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062130 puparial glue A extracellular matrix which attaches an organism to a substrate. CHEBI:88079 alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88079 GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_1904315 ionotropic neurotransmitter receptor activity involved in regulation of post-synaptic membrane potential|ionotropic neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential Any transmitter-gated ion channel activity that is involved in regulation of postsynaptic membrane potential. CHEBI:29775 selenol group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29775 GO:1904314 cellular response to methamphetamine hydrochloride biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904314 cellular response to methamphetamine HCL Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methamphetamine hydrochloride stimulus. GO:0062132 regulation of L-glutamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062132 Any process that modulates the rate, frequency or extent of L-glutamine biosynthesis. GO:1904313 response to methamphetamine hydrochloride biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904313 response to methamphetamine HCL Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methamphetamine hydrochloride stimulus. GO:0062131 3-butenylglucosinolate 2-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062131 MetaCyc:RXNQT-4343|RHEA:60628 But-3-enyl Glucosinolate-2-hydroxylase activity Catalysis of the reaction: gluconapin + a reduced electron acceptor + O2 = xi-progoitrin + an oxidized electron acceptor + H2O. GO:0062134 positive regulation of L-glutamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062134 Any process that starts, increases the frequency, rate or extent of L-glutamine biosynthesis. GO:1904312 cellular response to gold(3+) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904312 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gold(3+) stimulus. CHEBI:29772 hydroxyazanide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29772 GO:0062133 negative regulation of L-glutamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062133 Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamine biosynthesis. GO:1904311 response to gold(3+) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904311 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gold(3+) stimulus. GO:1904321 response to forskolin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904321 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a forskolin stimulus. GO:0062136 low-density lipoprotein receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062136 low-density lipoprotein particle receptor complex|LDL receptor complex|LDLR complex A plasma membrane protein complex capable of low-density lipoprotein particle receptor activity. It may also bind xenobiotic toxins and deliver them into the cell via endocytosis. While most substrates get degraded via the endosome the receptor is recycled to the plasma membrane. It may also act as a transducer of intracellular signal pathways and often acts in corporation with other cell-surface receptors. GO:1904320 positive regulation of smooth muscle contraction involved in micturition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904320 up regulation of urinary bladder smooth muscle contraction involved in micturition|upregulation of smooth muscle contraction involved in urination|positive regulation of urinary bladder smooth muscle contraction involved in micturition|up regulation of smooth muscle contraction involved in micturition|activation of smooth muscle contraction involved in micturition|activation of urinary bladder smooth muscle contraction involved in micturition|up regulation of smooth muscle contraction involved in urination|positive regulation of smooth muscle contraction involved in urination|up-regulation of urinary bladder smooth muscle contraction involved in micturition|activation of smooth muscle contraction involved in urination|up-regulation of smooth muscle contraction involved in micturition|upregulation of urinary bladder smooth muscle contraction involved in micturition|up-regulation of smooth muscle contraction involved in urination|upregulation of smooth muscle contraction involved in micturition Any process that activates or increases the frequency, rate or extent of smooth muscle contraction involved in micturition. GO:0062137 cargo receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062137 Any protein complex that is part of a membrane and which functions as a cargo receptor. NCBITaxon:2684882 Zygnematophycidae organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_2684882 GO:0062139 camera-type eye photoreceptor cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062139 The process whose specific outcome is the progression of a light-responsive receptor in a camera-type eye over time, from its formation to the mature structure. CHEBI:30763 4-hydroxybenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30763 GO:0003839 gamma-glutamylcyclotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003839 EC:4.3.2.9|Reactome:R-HSA-6785928|RHEA:20505|Reactome:R-HSA-1247922|MetaCyc:GAMMA-GLUTAMYLCYCLOTRANSFERASE-RXN gamma-L-glutamylcyclotransferase activity|(5-L-glutamyl)-L-amino-acid 5-glutamyltransferase (cyclizing)|gamma-glutamyl-amino acid cyclotransferase activity|L-glutamic cyclase activity Catalysis of the reaction: (5-L-glutamyl)-L-amino acid = 5-oxoproline + L-amino acid. CHEBI:30762 salicylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30762 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003836 MetaCyc:2.4.99.4-RXN|Reactome:R-HSA-1022129|Reactome:R-HSA-3656258|Reactome:R-HSA-981497|Reactome:R-HSA-2046285|EC:2.4.99.4|Reactome:R-HSA-9605600|RHEA:21616|Reactome:R-HSA-4084984|Reactome:R-HSA-1912378|Reactome:R-HSA-9603987 CMP-N-acetylneuraminate:beta-D-galactoside alpha-2,3-N-acetylneuraminyl-transferase activity|CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase activity Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-R = CMP + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-R. GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003835 MetaCyc:2.4.99.1-RXN|Reactome:R-HSA-4085033|Reactome:R-HSA-977071|Reactome:R-HSA-977228|Reactome:R-HSA-975902|EC:2.4.99.1|RHEA:11836 beta-galactosamide alpha-2,6-sialyltransferase activity|CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase activity|CMP-N-acetylneuraminate:beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine alpha-2,6-N-acetylneuraminyltransferase activity Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-(1->4)-acetyl-beta-D-glucosamine = CMP + alpha-N-acetylneuraminyl-(2->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine. GO:0003838 sterol 24-C-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003838 MetaCyc:RXN-11201|MetaCyc:RXN3O-178|RHEA:21128|EC:2.1.1.41 S-adenosyl-L-methionine:zymosterol 24-C-methyltransferase activity|phytosterol methyltransferase activity|delta24-sterol methyltransferase activity|delta(24)-sterol methyltransferase activity|S-adenosyl-4-methionine:sterol Delta(24)-methyltransferase activity|S-adenosyl-L-methionine:Delta24(23)-sterol methyltransferase activity|SMT1 activity|S-adenosyl-4-methionine:sterol delta24-methyltransferase activity|S-adenosyl-L-methionine:Delta(24(23))-sterol methyltransferase activity|delta(24)-methyltransferase activity|sterol 24C methyltransferase activity|zymosterol-24-methyltransferase activity|24-sterol C-methyltransferase activity|delta24-methyltransferase activity|delta(24)-sterol C-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 5-alpha-cholest-8,24-dien-3-beta-ol = S-adenosyl-L-homocysteine + 24-methylene-5-alpha-cholest-8-en-3-beta-ol. GO:0003837 beta-ureidopropionase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003837 EC:3.5.1.6|Reactome:R-HSA-73620|RHEA:11184|MetaCyc:BETA-UREIDOPROPIONASE-RXN|Reactome:R-HSA-73591 N-carbamoyl-beta-alanine amidohydrolase activity Catalysis of the reaction: N-carbamoyl-beta-alanine + H2O = beta-alanine + CO2 + NH3. GO:0003843 1,3-beta-D-glucan synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003843 EC:2.4.1.34|RHEA:21476|MetaCyc:13-BETA-GLUCAN-SYNTHASE-RXN beta-1,3-glucan synthetase activity|1,3-beta-D-glucan synthetase activity|UDP-glucose:1,3-beta-D-glucan 3-beta-D-glucosyltransferase activity|UDP-glucose-1,3-beta-glucan glucosyltransferase activity|UDP-glucose:(1,3)beta-glucan synthase activity|(1,3)-beta-glucan (callose) synthase activity|beta-1,3-glucan synthase activity|1,3-beta-D-glucan-UDP glucosyltransferase activity|UDP-glucose-1,3-beta-D-glucan glucosyltransferase activity|1,3-beta-glucan-uridine diphosphoglucosyltransferase activity|callose synthetase activity|paramylon synthetase|uridine diphosphoglucose-1,3-beta-glucan glucosyltransferase activity|GS-II|UDPglucose:1,3-beta-D-glucan 3-beta-D-glucosyltransferase activity|UDPglucose-1,3-beta-D-glucan glucosyltransferase activity|1,3-beta-glucan synthase activity|UDP-glucose-beta-glucan glucosyltransferase activity|callose synthase activity Catalysis of the reaction: UDP-glucose + [(1->3)-beta-D-glucosyl](n) = UDP + [(1->3)-beta-D-glucosyl](n+1). GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003842 Reactome:R-HSA-6784399|Reactome:R-HSA-70679|EC:1.2.1.88|RHEA:16417|MetaCyc:PYRROLINECARBDEHYDROG-RXN delta1-pyrroline-5-carboxylate dehydrogenase activity|1-pyrroline-5-carboxylate:NAD+ oxidoreductase activity|pyrroline-5-carboxylic acid dehydrogenase activity|1-pyrroline dehydrogenase|L-pyrroline-5-carboxylate-NAD+ oxidoreductase activity|pyrroline-5-carboxylate dehydrogenase activity Catalysis of the reaction: 1-pyrroline-5-carboxylate + NAD+ + H2O = L-glutamate + NADH + H(+). GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003845 Wikipedia:11beta-hydroxysteroid_dehydrogenase|Reactome:R-HSA-194023|MetaCyc:11-BETA-HYDROXYSTEROID-DEHYDROGENASE-RXN 11beta-hydroxy steroid dehydrogenase|corticosteroid 11beta-dehydrogenase|corticosteroid 11-reductase|11beta-hydroxysteroid dehydrogenase|dehydrogenase, 11beta-hydroxy steroid|beta-hydroxysteroid dehydrogenase Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD(P)+ = an 11-oxosteroid + NAD(P)H + H(+). CHEBI:88061 polyamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88061 GO:0003844 1,4-alpha-glucan branching enzyme activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003844 EC:2.4.1.18|Reactome:R-HSA-3878762|MetaCyc:GLYCOGEN-BRANCH-RXN|Reactome:R-HSA-3322005|Reactome:R-HSA-3322016|Reactome:R-HSA-3322057 glycogen branching enzyme activity|enzymatic branching factor|Q-enzyme|alpha-1,4-glucan:alpha-1,4-glucan-6-glycosyltransferase activity|1,4-glucan-6-(1,4-glucano)-transferase activity|amylo-(1,4 to 1,6)transglucosidase activity|plant branching enzyme|enzyme Q|branching enzyme activity|amylose isomerase activity|glucosan transglycosylase activity|branching glycosyltransferase activity|alpha-glucan-branching glycosyltransferase activity|amylo-(1,4->1,6)-transglycosylase activity|starch branching enzyme|1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-alpha-D-(1,4-alpha-D-glucano)-transferase activity Catalysis of the transfer of a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxyl group in a similar glucan chain. CHEBI:88060 ganglioside GP1(5-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88060 CHEBI:30779 succinate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30779 CHEBI:30778 gallic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30778 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003841 Reactome:R-HSA-1482636|RHEA:19709|Reactome:R-HSA-75885|EC:2.3.1.51|Reactome:R-HSA-1482689|Reactome:R-HSA-1482539|Reactome:R-HSA-1482894|Reactome:R-HSA-1482548|Reactome:R-HSA-1482667|Reactome:R-HSA-1482547|MetaCyc:RXN-1623|Reactome:R-HSA-1482598|Reactome:R-HSA-8849345 1-acyl-sn-glycerol-3-phosphate acyltransferase activity|lysophosphatidate acyltransferase activity|acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase activity|lysophosphatidic acid-acyltransferase activity|1-acyl-sn-glycerol 3-phosphate acyltransferase activity|1-acyl-sn-glycero-3-phosphate acyltransferase activity|1-acylglycerolphosphate acyltransferase activity|1-acylglycero-3-phosphate acyltransferase activity|1-acylglycerophosphate acyltransferase activity Catalysis of the reaction: acyl-CoA + 1-acyl-sn-glycerol-3-phosphate = CoA + 1,2-diacyl-sn-glycerol-3-phosphate. CHEBI:30776 hexanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30776 CHEBI:88065 (24R,25R)-3alpha,7alpha,24-trihydroxy-5beta-cholestan-26-oyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88065 CHEBI:30775 fluoroacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30775 GO:0003840 obsolete gamma-glutamyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003840 KEGG_REACTION:R04159|MetaCyc:GAMMA-GLUTAMYLTRANSFERASE-RXN|EC:2.3.2.2 L-glutamyltransferase activity|alpha-glutamyl transpeptidase activity|gamma-glutamyl peptidyltransferase activity|(5-L-glutamyl)-peptide:amino-acid 5-glutamyltransferase activity|gamma-GPT|L-gamma-glutamyl transpeptidase activity|gamma-glutamyl transpeptidase activity|gamma-GTP|glutamyl transpeptidase activity|gamma-GT|L-gamma-glutamyltransferase activity OBSOLETE. Catalysis of the reaction: (5-L-glutamyl)-peptide + an amino acid = peptide + 5-L-glutamyl-amino acid. CHEBI:88064 (24E)-3alpha,7alpha-dihydroxy-5beta-cholest-24-en-26-oyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88064 CHEBI:29785 nitro group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29785 GO:1904329 negative regulation of myofibroblast contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904329 inhibition of MF contraction|inhibition of MFB contraction|down-regulation of myofibroblast contraction|inhibition of myofibroblast contraction|down regulation of MFB contraction|down-regulation of MF contraction|negative regulation of MF contraction|downregulation of MFB contraction|down regulation of myofibroblast contraction|downregulation of MF contraction|down-regulation of MFB contraction|negative regulation of MFB contraction|down regulation of MF contraction|downregulation of myofibroblast contraction Any process that stops, prevents or reduces the frequency, rate or extent of myofibroblast contraction. CHEBI:88067 (2E,5Z)-tetradecadienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88067 GO:1904328 regulation of myofibroblast contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904328 regulation of MFB contraction|regulation of MF contraction Any process that modulates the frequency, rate or extent of myofibroblast contraction. CHEBI:88066 dioctanoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88066 GO:1904327 protein localization to cytosolic proteasome complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904327 protein localisation to cytosolic proteasome complex|protein localisation in cytosolic proteasome complex|protein localization in cytosolic proteasome complex A process in which a protein is transported to, or maintained in, a location within a cytosolic proteasome complex. CHEBI:88069 beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-Cer biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88069 GO:1904326 negative regulation of circadian sleep/wake cycle, wakefulness biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904326 down-regulation of circadian sleep/wake cycle, wakefulness|inhibition of circadian sleep/wake cycle, wakefulness|down regulation of circadian sleep/wake cycle, wakefulness|downregulation of circadian sleep/wake cycle, wakefulness Any process that stops, prevents or reduces the frequency, rate or extent of circadian sleep/wake cycle, wakefulness. CHEBI:88068 monosialomonoglycosylceramide(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88068 GO:1904325 positive regulation of inhibitory G protein-coupled receptor phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904325 up-regulation of inhibitory G-protein coupled receptor phosphorylation|positive regulation of inhibitory G-protein coupled receptor phosphorylation|upregulation of inhibitory G-protein coupled receptor phosphorylation|up regulation of inhibitory G-protein coupled receptor phosphorylation|activation of inhibitory G-protein coupled receptor phosphorylation Any process that activates or increases the frequency, rate or extent of inhibitory G protein-coupled receptor phosphorylation. GO:0062121 linear element maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062121 LinE chromosome loading|LinE focus formation The meiotic cell cycle chromosome organization process in which LinE complexes closely associate with chromatin during meiotic prophase to form mature linear elements. GO:1904324 negative regulation of inhibitory G protein-coupled receptor phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904324 down-regulation of inhibitory G-protein coupled receptor phosphorylation|inhibition of inhibitory G-protein coupled receptor phosphorylation|negative regulation of inhibitory G-protein coupled receptor phosphorylation|down regulation of inhibitory G-protein coupled receptor phosphorylation|downregulation of inhibitory G-protein coupled receptor phosphorylation Any process that stops, prevents or reduces the frequency, rate or extent of inhibitory G protein-coupled receptor phosphorylation. GO:0062120 LinE complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062120 The aggregation, arrangement and bonding together of a set of components during meiotic prophase to form a LinE complex, the protein complex that associates with chromatin to form linear elements in fission yeast. In S. pombe, the LinE complex contains four main structural components (Rec10, Rec25, Rec27, and Mug20) and other associated proteins. CHEBI:29780 isochorismate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29780 GO:0062123 regulation of linear element maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062123 Any process that modulates the rate, frequency or extent of linear element maturation. GO:1904323 regulation of inhibitory G protein-coupled receptor phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904323 regulation of inhibitory G-protein coupled receptor phosphorylation Any process that modulates the frequency, rate or extent of inhibitory G protein-coupled receptor phosphorylation. GO:0062122 histone methyltransferase activity (H3-K37 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062122 histone lysine N-methyltransferase activity (H3-K37 specific) Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 37) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 37). This reaction is the addition of a methyl group onto lysine at position 37 of the histone H3 protein. GO:1904322 cellular response to forskolin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904322 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a forskolin stimulus. GO:1904332 negative regulation of error-prone translesion synthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904332 down-regulation of mutagenic PRR|negative regulation of mutagenic PRR|inhibition of error-prone translesion synthesis|downregulation of mutagenic postreplication DNA repair|down-regulation of error-prone postreplication DNA repair|negative regulation of error-prone postreplication DNA repair|inhibition of mutagenic PRR|down regulation of mutagenic postreplication DNA repair|downregulation of error-prone postreplication DNA repair|inhibition of mutagenic postreplication DNA repair|down regulation of error-prone translesion synthesis|down regulation of error-prone postreplication DNA repair|downregulation of error-prone translesion synthesis|down regulation of mutagenic PRR|inhibition of error-prone postreplication DNA repair|downregulation of mutagenic PRR|down-regulation of mutagenic postreplication DNA repair|negative regulation of mutagenic postreplication DNA repair|down-regulation of error-prone translesion synthesis Any process that stops, prevents or reduces the frequency, rate or extent of error-prone translesion synthesis. GO:0062125 regulation of mitochondrial gene expression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062125 Any process that modulates the frequency, rate or extent of mitochondrial gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). GO:1904331 regulation of error-prone translesion synthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904331 regulation of mutagenic postreplication DNA repair|regulation of error-prone postreplication DNA repair|regulation of mutagenic PRR Any process that modulates the frequency, rate or extent of error-prone translesion synthesis. GO:0062124 4-hydroxybutyrate receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062124 gamma-hydroxybutyrate receptor activity Combining with 4-hydroxybutyrte to initiate a change in cell activity. GO:0062127 fatty acid primary amide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062127 primary fatty amide catabolic process The chemical reactions and pathways resulting in the breakdown of primary fatty amides. GO:1904330 positive regulation of myofibroblast contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904330 up regulation of MF contraction|up regulation of MFB contraction|upregulation of myofibroblast contraction|positive regulation of MFB contraction|activation of MFB contraction|upregulation of MF contraction|up regulation of myofibroblast contraction|activation of myofibroblast contraction|up-regulation of MFB contraction|up-regulation of MF contraction|activation of MF contraction|upregulation of MFB contraction|up-regulation of myofibroblast contraction|positive regulation of MF contraction Any process that activates or increases the frequency, rate or extent of myofibroblast contraction. GO:0062126 fatty acid primary amide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062126 primary fatty amide metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform primary fatty amides. GO:0062129 chitin-based extracellular matrix biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062129 chitin-based ECM Any constituent part of a chitin-based noncellular, hardened, or membranous extracellular matrix secreted from the apical surface of an epithelial sheet. GO:0062128 MutSgamma complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062128 Msh4-Msh5 complex A heterodimer involved in the stabilization of DNA recombination intermediates, the promotion of crossover recombination, and the proper assembly of the synaptonemal complex in meiotic prophase nuclei. In yeast the complex consists of two subunits, Msh4 and Msh5. CHEBI:30772 butyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30772 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0003847 EC:3.1.1.47|Reactome:R-HSA-8869206|RHEA:17777|MetaCyc:3.1.1.47-RXN LDL-PLA(2) activity|LDL-associated phospholipase A2|PAF 2-acylhydrolase activity|alkylacetyl-GPC:acetylhydrolase activity|1-alkyl-2-acetyl-sn-glycero-3-phosphocholine acetylhydrolase activity|LDL-associated phospholipase A(2) activity|1-alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase activity|PAF acetylhydrolase activity|LDL-PLA2|platelet-activating factor acetylhydrolase activity|2-acetyl-1-alkylglycerophosphocholine esterase activity Catalysis of the reaction: 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine + H2O = 1-alkyl-sn-glycero-3-phosphocholine + acetate. GO:0003846 2-acylglycerol O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003846 Reactome:R-HSA-6800334|EC:2.3.1.22|Reactome:R-HSA-5696448|RHEA:16741|MetaCyc:2-ACYLGLYCEROL-O-ACYLTRANSFERASE-RXN acylglycerol palmitoyltransferase activity|acyl-CoA:2-acylglycerol O-acyltransferase activity|monoglyceride acyltransferase activity|monoacylglycerol acyltransferase activity|acyl coenzyme A-monoglyceride acyltransferase activity Catalysis of the reaction: acyl-CoA + 2-acylglycerol = CoA + diacylglycerol. GO:0003849 3-deoxy-7-phosphoheptulonate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003849 KEGG_REACTION:R01826|RHEA:14717|EC:2.5.1.54|MetaCyc:DAHPSYN-RXN 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate|2-dehydro-3-deoxy-phosphoheptonate aldolase activity|phospho-2-dehydro-3-deoxyheptonate aldolase activity|phospho-2-keto-3-deoxyheptonate aldolase activity|phosphoenolpyruvate:D-erythrose-4-phosphate C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming)|7-phospho-2-keto-3-deoxy-D-arabino-heptonate D-erythrose-4-phosphate lyase (pyruvate-phosphorylating) activity|D-erythrose-4-phosphate-lyase activity|KDPH synthetase activity|phospho-2-keto-3-deoxyheptonic aldolase activity|3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase activity|DS-Mn activity|phospho-2-keto-3-deoxyheptanoate aldolase activity|7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate D-erythrose-4-phosphate lyase (pyruvate-phosphorylating) activity|DHAP synthase activity|KDPH synthase activity|DAH7-P synthase activity|3-deoxy-D-arabino-2-heptulosonic acid 7-phosphate synthetase activity|DS-Co activity|D-erythrose-4-phosphate-lyase (pyruvate-phosphorylating) activity|2-dehydro-3-deoxyphosphoheptonate aldolase activity|phospho-2-oxo-3-deoxyheptonate aldolase activity|2-keto-3-deoxy-D-arabino-heptonic acid 7-phosphate synthetase activity|3-deoxy-D-arabino-heptolosonate-7-phosphate synthetase activity|DAHP synthase activity|deoxy-D-arabino-heptulosonate-7-phosphate synthetase activity Catalysis of the reaction: D-erythrose 4-phosphate + H(2)O + phosphoenolpyruvate = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate. GO:0003848 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0003848 KEGG_REACTION:R03503|MetaCyc:H2PTERIDINEPYROPHOSPHOKIN-RXN|RHEA:11412|EC:2.7.6.3 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase activity|7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase activity|7,8-dihydro-6-hydroxymethylpterin diphosphokinase activity|6-hydroxymethyl-7,8-dihydropterin diphosphokinase activity|2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase activity|H2-pteridine-CH2OH pyrophosphokinase activity|7,8-dihydroxymethylpterin-pyrophosphokinase activity|HPPK|hydroxymethyldihydropteridine pyrophosphokinase activity|ATP:2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine 6'-diphosphotransferase activity Catalysis of the reaction: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + ATP = (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate + AMP + 2 H(+). GO:0003810 protein-glutamine gamma-glutamyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003810 Reactome:R-HSA-140851|Reactome:R-HSA-6810894|MetaCyc:2.3.2.13-RXN|RESID:AA0124|RHEA:54816|EC:2.3.2.13 fibrin stabilizing factor|glutaminylpeptide gamma-glutamyltransferase activity|polyamine transglutaminase activity|R-glutaminyl-peptide:amine gamma-glutamyl transferase activity|factor XIIIa|protein-glutamine:amine gamma-glutamyltransferase|transglutaminase activity|tissue transglutaminase|TGase activity|fibrinoligase activity Catalysis of the reaction: protein glutamine + alkylamine = protein N5-alkylglutamine + NH3. This reaction is the formation of the N6-(L-isoglutamyl)-L-lysine isopeptide, resulting in cross-linking polypeptide chains; the gamma-carboxamide groups of peptidyl-glutamine residues act as acyl donors, and the 6-amino-groups of peptidyl-lysine residues act as acceptors, to give intra- and intermolecular N6-(5-glutamyl)lysine cross-links. CHEBI:30749 4-chlorophenylacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30749 CHEBI:30748 2,4-dichlorobenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30748 CHEBI:88091 6-deoxy-6-sulfoglucono-1,5-lactone(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88091 GO:0003812 obsolete alternative-complement-pathway C3/C5 convertase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003812 alternative complement pathway C3(C5) convertase activity|proenzyme factor B|alternative-complement-pathway C3/C5 convertase activity|complement factor B activity|C3b,Bb,CVF,Bb,C5 convertase activity|(CVF)-dependent glycine-rich-beta-glucoprotein|complement component C3/C5 convertase (alternative) activity|complement C 3(C 5) convertase (amplification)|(C3b)n,Bb|heat-labile factor|C5 convertase activity|cobra venom factor-dependent C3 convertase|C3 convertase activity|CVF,Bb|C3 proactivator|glycine-rich beta-glycoprotein|properdin factor B activity OBSOLETE. Catalysis of the cleavage of Arg-Ser bond in complement component C3 alpha-chain to yield C3a and C3b, and Arg bond in complement component C5 alpha-chain to yield C5a and C5b. CHEBI:30747 4-chlorobenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30747 CHEBI:616459 carbamimidoylazanium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_616459 CHEBI:88094 2-dehydro-3,6-dideoxy-6-sulfo-D-gluconate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88094 GO:0003811 obsolete complement activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003811 complement activity OBSOLETE. Any of a set of activities involved in the complement cascade. CHEBI:30746 benzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30746 CHEBI:88093 6-deoxy-6-sulfo-D-gluconate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88093 CHEBI:88096 N-hexanoylphytosphingosine 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88096 CHEBI:30745 phenylacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30745 CHEBI:30744 oxaloacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30744 CHEBI:88095 N-hexanoylphytosphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88095 CHEBI:88098 3beta,12alpha-dihydroxy-5beta-cholan-24-oic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88098 CHEBI:88097 7alpha-hydroxy-3-oxo-5beta-cholan-24-oic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88097 CHEBI:30742 ethylene glycol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30742 GO:0062150 amorpha-4,11-diene 12-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062150 RHEA:32999|EC:1.14.14.114 Catalysis of the reaction:(+)-amorpha-4,11-diene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = (+)-artemisinate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]. CHEBI:88099 D-3-sulfolactaldehyde(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88099 GO:1904339 negative regulation of dopaminergic neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904339 down regulation of dopaminergic neuron differentiation|downregulation of dopaminergic neuron differentiation|down-regulation of dopaminergic neuron differentiation|inhibition of dopaminergic neuron differentiation Any process that stops, prevents or reduces the frequency, rate or extent of dopaminergic neuron differentiation. CHEBI:29751 (-)-quinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29751 GO:1904338 regulation of dopaminergic neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904338 Any process that modulates the frequency, rate or extent of dopaminergic neuron differentiation. GO:0062152 mRNA (cytidine-5-)-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062152 RHEA:61464 mRNA (cytosine-5-)-methyltransferase activity Catalysis of the reaction: a cytidine in mRNA + S-adenosyl-L-methionine = a 5-methylcytidine in mRNA + H(+) + S-adenosyl-L-homocysteine. CHEBI:29754 arsonate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29754 GO:1904337 positive regulation of ductus arteriosus closure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904337 upregulation of ductus arteriosus closure|up regulation of ductus arteriosus closure|activation of ductus arteriosus closure|up-regulation of ductus arteriosus closure Any process that activates or increases the frequency, rate or extent of ductus arteriosus closure. GO:0062151 catalase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062151 A protein-containing complex that is capable of catalase activity. CHEBI:29753 arsonite(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29753 GO:1904336 negative regulation of ductus arteriosus closure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904336 down regulation of ductus arteriosus closure|downregulation of ductus arteriosus closure|down-regulation of ductus arteriosus closure|inhibition of ductus arteriosus closure Any process that stops, prevents or reduces the frequency, rate or extent of ductus arteriosus closure. GO:0062154 N6-mAMP deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062154 RHEA:16001 MAPDA Catalysis of the reaction: H(+) + H2O + N6-methyl-AMP = IMP + methylamine. GO:0062153 C5-methylcytidine-containing RNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062153 C5-methylcytosine-containing RNA binding Interacting selectively and non-covalently with an RNA molecule modified by C5-methylcytidine. GO:1904335 regulation of ductus arteriosus closure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904335 Any process that modulates the frequency, rate or extent of ductus arteriosus closure. GO:1904334 heme import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904334 heme assimilation The directed movement of heme from outside of a cell, across the plasma membrane and into the cytosol. GO:0062156 mitochondrial ATP-gated potassium channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062156 mitochondrial potassium channel activity|mitoK-ATP activity Enables the ATP-dependent diffusion of a potassium ion across the mitochondrial inner membrane. CHEBI:29750 3-(indol-3-yl)pyruvic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29750 GO:1904333 positive regulation of error-prone translesion synthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904333 up regulation of mutagenic postreplication DNA repair|activation of error-prone postreplication DNA repair|up-regulation of error-prone translesion synthesis|positive regulation of error-prone postreplication DNA repair|up-regulation of mutagenic PRR|upregulation of mutagenic postreplication DNA repair|up regulation of error-prone postreplication DNA repair|upregulation of error-prone translesion synthesis|upregulation of mutagenic PRR|up-regulation of mutagenic postreplication DNA repair|upregulation of error-prone postreplication DNA repair|up regulation of error-prone translesion synthesis|activation of error-prone translesion synthesis|activation of mutagenic postreplication DNA repair|up regulation of mutagenic PRR|up-regulation of error-prone postreplication DNA repair|positive regulation of mutagenic PRR|activation of mutagenic PRR|positive regulation of mutagenic postreplication DNA repair Any process that activates or increases the frequency, rate or extent of error-prone translesion synthesis. GO:0062155 curli secretion complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062155 A protein-containing complex that serves as a channel for the secretion of curli. Curli are a fibers that serve as a major component of the extracellular matrix of pellicle biofilms. GO:1904343 positive regulation of colon smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904343 up-regulation of colon smooth muscle contraction|upregulation of colon smooth muscle contraction|up regulation of colon smooth muscle contraction|activation of colon smooth muscle contraction Any process that activates or increases the frequency, rate or extent of colon smooth muscle contraction. GO:0062158 chloride:proton antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062158 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: chloride(out) + proton(in) = chloride(in) + proton(out). GO:0062157 mitochondrial ATP-gated potassium channel complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062157 A protein-containing complex that is capable of the ATP-dependent diffusion of a potassium ion across the mitochondrial inner membrane. GO:1904342 negative regulation of colon smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904342 inhibition of colon smooth muscle contraction|down regulation of colon smooth muscle contraction|downregulation of colon smooth muscle contraction|down-regulation of colon smooth muscle contraction Any process that stops, prevents or reduces the frequency, rate or extent of colon smooth muscle contraction. GO:1904341 regulation of colon smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904341 Any process that modulates the frequency, rate or extent of colon smooth muscle contraction. GO:1904340 positive regulation of dopaminergic neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904340 up-regulation of dopaminergic neuron differentiation|upregulation of dopaminergic neuron differentiation|up regulation of dopaminergic neuron differentiation|activation of dopaminergic neuron differentiation Any process that activates or increases the frequency, rate or extent of dopaminergic neuron differentiation. GO:0062159 contractile vacuole complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062159 CVC A non-membrane-bounded organelle of eukaryotic cells, especially Protozoa, that fills with water from the cytoplasm and then discharges this externally. One of its functions is osmoregulatory. GO:0003818 obsolete complement factor I activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003818 complement C4bi|factor I|C3b/C4b inactivator activity|complement component C3b inactivator activity|complement C3b/C4b inactivator|C3bINA|complement C3b inactivator|complement C4b inactivator|complement factor I activity|conglutinogen-activating factor C|C3b inactivator activity OBSOLETE. Catalysis of the inactivation of complement subcomponents C3b, iC3b and C4b by proteolytic cleavage. GO:0003817 obsolete complement factor D activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003817 adipsin|factor D|C3 convertase activator activity|properdin factor D esterase activity|factor D (complement)|complement factor D activity|C3 proactivator convertase activity OBSOLETE. Catalysis of the cleavage of component factor B (Arg-Lys) when in complex with C3b or with cobra venom factor (CVF). GO:0003819 obsolete major histocompatibility complex antigen biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003819 MHC protein|major histocompatibility complex antigen OBSOLETE. (Was not defined before being made obsolete). GO:0003813 obsolete classical-complement-pathway C3/C5 convertase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003813 C423|C4b,2a,3b|C4b,2a|complement C42|C42|complement C2 activity|C5 convertase activity|complement C3 convertase activity|C3 convertase activity|classical-complement-pathway C3/C5 convertase activity OBSOLETE. Catalysis of the selective cleavage of Arg-Ser bond in complement component C3 alpha-chain to form C3a and C3b, and Arg bond in complement component C5 alpha-chain to form C5a and C5b. GO:0003816 obsolete complement component C1s activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003816 C1s esterase activity|complement component C1s activity|complement C1s|C1 esterase activity|complement subcomponent C1s|activated complement C1s OBSOLETE. Catalysis of the cleavage of component C4 to C4a and C4b (Arg-Ala bond), and component C2 to C2a and C2b (Lys-Lys or Arg-Lys bond). GO:0003815 obsolete complement component C1r activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003815 C1r esterase activity|complement component C1r activity|complement subcomponent C1r|activated complement C1r OBSOLETE. Catalysis of the selective cleavage of Lys(or Arg)-Ile bond in complement subcomponent C1s to form the active form of C1s (EC:3.4.21.42). UBERON:2005260 fenestrated capillary biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_2005260 fenestrated capillary vessel|fenestrated blood vessel endothelium Capillary that has pores in the endothelial cells (60-80 nm in diameter) that are spanned by a diaphragm of radially oriented fibrils and allow small molecules and limited amounts of protein to diffuse GO:0003821 obsolete class II major histocompatibility complex antigen biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003821 class II major histocompatibility complex antigen OBSOLETE. (Was not defined before being made obsolete). CHEBI:88081 fatty acid anion 23:0 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88081 GO:0003820 obsolete class I major histocompatibility complex antigen biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003820 class I major histocompatibility complex antigen OBSOLETE. (Was not defined before being made obsolete). CHEBI:88080 (5Z)-3-oxotetradecenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88080 GO:0003823 antigen binding biolink:MolecularActivity go-plus goslim_chembl|goslim_pir http://purl.obolibrary.org/obo/GO_0003823 immunoglobulin|opsonin activity|B cell receptor activity|antibody Interacting selectively and non-covalently with an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen. CHEBI:88083 (3E)-tetradecenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88083 GO:0003822 obsolete MHC-interacting protein biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003822 MHC-interacting protein OBSOLETE. (Was not defined before being made obsolete). CHEBI:88084 (2E,4E)-tetradecadienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88084 CHEBI:30754 anthranilic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30754 CHEBI:88087 (3S,7Z)-3-hydroxyhexadecenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88087 CHEBI:88086 (2E,7Z)-hexadecadienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88086 CHEBI:30753 4-aminobenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30753 CHEBI:88089 alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-L-Fuc-(1->4)]-[alpha-Neu5Ac-(2->6)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88089 CHEBI:88088 alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-L-Fuc-(1->4)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88088 GO:0062141 nuclear exosome targeting complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062141 NEXT complex A protein-containing complex that functions with the RNA exosome and contributes to the degradation of abberant transcripts. GO:1904349 positive regulation of small intestine smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904349 up regulation of small intestine smooth muscle contraction|activation of small intestine smooth muscle contraction|up-regulation of small intestine smooth muscle contraction|upregulation of small intestine smooth muscle contraction Any process that activates or increases the frequency, rate or extent of small intestine smooth muscle contraction. GO:0062140 hyphae septin collar biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062140 septin collar of invasive hyphae A septin collar in pathogenic fungi involved in the constriction of hyphae at the plant plasmodesma enabling penetration of an adjacent cell. GO:1904348 negative regulation of small intestine smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904348 down regulation of small intestine smooth muscle contraction|downregulation of small intestine smooth muscle contraction|down-regulation of small intestine smooth muscle contraction|inhibition of small intestine smooth muscle contraction Any process that stops, prevents or reduces the frequency, rate or extent of small intestine smooth muscle contraction. GO:1904347 regulation of small intestine smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904347 Any process that modulates the frequency, rate or extent of small intestine smooth muscle contraction. GO:0062143 L-propargylglycine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062143 The chemical reactions and pathways resulting in the formation of L-propargylglycine (Pra). L-propargylglycine is an antibiotic produced by Streptomyces bacteria. GO:1904346 positive regulation of gastric mucosal blood circulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904346 activation of stomach mucosal blood circulation|positive regulation of stomach mucosal blood circulation|up-regulation of gastric mucosal blood circulation|upregulation of gastric mucosal blood circulation|up-regulation of stomach mucosal blood circulation|up regulation of gastric mucosal blood circulation|upregulation of stomach mucosal blood circulation|activation of gastric mucosal blood circulation|up regulation of stomach mucosal blood circulation Any process that activates or increases the frequency, rate or extent of gastric mucosal blood circulation. GO:0062142 L-beta-ethynylserine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062142 The chemical reactions and pathways resulting in the formation of L-beta-ethynylserine. L-beta-ethynylserine is an antibiotic produced by Streptomyces bacteria. GO:1904345 negative regulation of gastric mucosal blood circulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904345 inhibition of gastric mucosal blood circulation|negative regulation of stomach mucosal blood circulation|down-regulation of stomach mucosal blood circulation|inhibition of stomach mucosal blood circulation|down regulation of gastric mucosal blood circulation|downregulation of gastric mucosal blood circulation|down regulation of stomach mucosal blood circulation|down-regulation of gastric mucosal blood circulation|downregulation of stomach mucosal blood circulation Any process that stops, prevents or reduces the frequency, rate or extent of gastric mucosal blood circulation. GO:0062145 L-propargylglycine--L-glutamate ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062145 RHEA:59896 Catalysis of the reaction: ATP + L-glutamate + L-propargylglycine = ADP + H(+) + L-gamma-glutamyl-L-propargylglycine + phosphate. GO:0062144 L-propargylglycine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062144 RHEA:59892 Catalysis of the reaction: L-2-amino-4-chloropent-4-enoate = chloride + H(+) + L-propargylglycine. GO:1904344 regulation of gastric mucosal blood circulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904344 regulation of stomach mucosal blood circulation Any process that modulates the frequency, rate or extent of gastric mucosal blood circulation. GO:0062147 L-lysine 4-chlorinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062147 RHEA:59884 Catalysis of the reaction: 2-oxoglutarate + chloride + H(+) + L-lysine + O2 = 4-chloro-L-lysine + CO2 + H2O + succinate. GO:1904354 negative regulation of telomere capping biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904354 down-regulation of telomere capping|down-regulation of telomere end protection|negative regulation of telomere end protection|inhibition of telomere end protection|downregulation of telomere capping|down regulation of telomere capping|inhibition of telomere capping|down regulation of telomere end protection|downregulation of telomere end protection Any process that stops, prevents or reduces the frequency, rate or extent of telomere capping. GO:0086103 G protein-coupled receptor signaling pathway involved in heart process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086103 G-protein coupled receptor signaling pathway involved in heart process|GPCR signaling pathway involved in heart process|GPCR signaling pathway involved in cardiac process|G-protein coupled receptor signalling pathway involved in heart process An G protein-coupled receptor signaling pathway which contributes to a circulatory system process carried out by the heart. GO:0062146 4-chloro-allylglycine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062146 RHEA:59888 Catalysis of the reaction: 4-chloro-L-lysine + AH2 + O2 = A + formaldehyde + H2O + L-2-amino-4-chloropent-4-enoate + NH4(+). GO:1904353 regulation of telomere capping biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904353 regulation of telomere end protection Any process that modulates the frequency, rate or extent of telomere capping. GO:0086102 adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086102 Gi-coupled G-protein coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate|muscarinic receptor signalling pathway involved in negative regulation of heart rate by inhibition of funny current|AC-inhibiting muscarinic receptor signaling pathway involved in negative regulation of heart rate|adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate|G-protein coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate via inhibition of adenylate cyclase activity|muscarinic receptor signalling pathway involved in negative regulation of heart rate by inhibition of If channel A G protein-coupled acetylcholine receptor signaling pathway that contributes to an decrease in frequency or rate of heart contraction through inhibition of adenylate cyclase (AC) activity. Binding of acetylcholine to a G protein-coupled (muscarinic) receptor on the surface of the signal-receiving cell results in the activation of an intracellular Gi/o protein. Gi/o inhibits adenylate cyclase to decrease cyclic-AMP (cAMP) levels. Since cAMP binds directly to F-channels to allow an inward flow of sodium (funny current, If current), a reduction in cAMP reduces the funny current to bring about membrane hyperpolarization and a decrease in heart rate. GO:1904352 positive regulation of protein catabolic process in the vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904352 activation of vacuolar protein catabolic process|activation of protein catabolic process in the vacuole|positive regulation of vacuolar protein breakdown|up regulation of vacuolar protein catabolism|positive regulation of vacuolar protein catabolism|up regulation of vacuolar protein breakdown|positive regulation of vacuolar protein catabolic process|up regulation of vacuolar protein catabolic process|upregulation of vacuolar protein degradation|activation of vacuolar protein catabolism|up regulation of protein catabolic process in the vacuole|upregulation of vacuolar protein breakdown|up-regulation of vacuolar protein catabolism|up-regulation of vacuolar protein degradation|upregulation of vacuolar protein catabolic process|up-regulation of vacuolar protein breakdown|upregulation of protein catabolic process in the vacuole|upregulation of vacuolar protein catabolism|activation of vacuolar protein degradation|up-regulation of vacuolar protein catabolic process|activation of vacuolar protein breakdown|positive regulation of vacuolar protein degradation|up regulation of vacuolar protein degradation|up-regulation of protein catabolic process in the vacuole Any process that activates or increases the frequency, rate or extent of protein catabolic process in the vacuole. GO:0062149 detection of stimulus involved in sensory perception of pain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062149 The series of events involved in the perception of pain in which a stimulus is received and converted into a molecular signal. GO:0086101 endothelin receptor signaling pathway involved in heart process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086101 endothelin receptor signalling pathway involved in heart process An endothelin receptor signaling pathway which contributes to a circulatory system process carried out by the heart. GO:1904351 negative regulation of protein catabolic process in the vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904351 downregulation of vacuolar protein degradation|down-regulation of vacuolar protein catabolic process|negative regulation of vacuolar protein catabolic process|down regulation of vacuolar protein degradation|downregulation of vacuolar protein breakdown|down-regulation of protein catabolic process in the vacuole|negative regulation of vacuolar protein catabolism|down-regulation of vacuolar protein catabolism|downregulation of vacuolar protein catabolic process|down regulation of vacuolar protein breakdown|inhibition of vacuolar protein degradation|down regulation of vacuolar protein catabolic process|downregulation of protein catabolic process in the vacuole|inhibition of vacuolar protein breakdown|inhibition of vacuolar protein catabolism|down regulation of protein catabolic process in the vacuole|inhibition of protein catabolic process in the vacuole|inhibition of vacuolar protein catabolic process|down-regulation of vacuolar protein degradation|negative regulation of vacuolar protein degradation|down regulation of vacuolar protein catabolism|negative regulation of vacuolar protein breakdown|down-regulation of vacuolar protein breakdown|downregulation of vacuolar protein catabolism Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process in the vacuole. GO:0086100 endothelin receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0086100 endothelin signaling pathway A series of molecular signals initiated by an endothelin receptor binding to one of its physiological ligands, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. Ends with regulation of a downstream cellular process, e.g. transcription. GO:0062148 L-gamma-glutamyl-L-propargylglycine hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062148 RHEA:59900 Catalysis of the reaction: 2-oxoglutarate + L-gamma-glutamyl-L-propargylglycine + O2 = CO2 + L-gamma-glutamyl-(3R)-L-beta-ethynylserine + succinate. GO:1904350 regulation of protein catabolic process in the vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904350 regulation of vacuolar protein degradation|regulation of vacuolar protein breakdown|regulation of vacuolar protein catabolic process|regulation of vacuolar protein catabolism Any process that modulates the frequency, rate or extent of protein catabolic process in the vacuole. CHEBI:15138 sulfide(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15138 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003829 Reactome:R-HSA-914018|Reactome:R-HSA-914012|RHEA:18705|MetaCyc:2.4.1.102-RXN|EC:2.4.1.102 O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I activity|core 2 acetylglucosaminyltransferase activity|core 6-beta-GlcNAc-transferase A|UDP-N-acetyl-D-glucosamine:O-glycosyl-glycoprotein (N-acetyl-D-glucosamine to N-acetyl-D-galactosamine of beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-R) beta-1,6-N-acetyl-D-glucosaminyltransferase activity|beta6-N-acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-mucin beta-(1,6)-acetylglucosaminyltransferase activity|beta(6)-N-acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-mucin beta-(1->6)-acetylglucosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-(1->3)-N-acetyl-D-galactosaminyl-R = UDP + beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-D-galactosaminyl-R. GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003828 Reactome:R-HSA-422454|EC:2.4.99.8|Reactome:R-HSA-1022133|MetaCyc:2.4.99.8-RXN|Reactome:R-HSA-4084978|RHEA:19313 GD3 synthase activity|SAT-2|ganglioside GD3 synthase activity|CMP-NeuAc:LM1(alpha-2,8) sialyltranferase activity|CMP-N-acetylneuraminate:alpha-N-acetylneuraminyl-2,3-beta-D-galactoside alpha-2,8-N-acetylneuraminyltransferase activity|cytidine monophosphoacetylneuraminate-ganglioside GM3|ganglioside GD3 synthetase sialyltransferase activity|alpha-2,8-sialyltransferase activity|alpha-N-acetylneuraminide alpha-2,8-sialyltransferase activity|CMP-NeuAc:LM1 alpha-(2->8)-sialyltranferase activity Catalysis of the reaction: CMP-N-acetylneuraminate + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R = CMP + alpha-N-acetylneuraminyl-(2->8)-alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R. CHEBI:30751 formic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30751 GO:0003825 alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003825 EC:2.4.1.15|RHEA:18889|MetaCyc:TREHALOSE6PSYN-RXN trehalose-phosphate synthase activity|UDP-glucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase activity|uridine diphosphoglucose phosphate glucosyltransferase activity|UDP-glucose-glucose-phosphate glucosyltransferase activity|trehalosephosphate-UDP glucosyl transferase activity|alpha,alpha-trehalose phosphate synthase (UDP-forming)|trehalose-P synthetase activity|phosphotrehalose-uridine diphosphate transglucosylase activity|trehalose 6-phosphate synthase activity|trehalosephosphate-UDP glucosyltransferase activity|trehalose phosphate synthetase activity|UDP-glucose-glucosephosphate glucosyltransferase activity|transglucosylase activity|UDPglucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase activity|trehalose-phosphate synthetase activity|UDPglucose-glucose-phosphate glucosyltransferase activity|trehalose phosphate synthase activity|trehalose phosphate-uridine diphosphate glucosyltransferase activity|trehalose 6-phosphate synthetase activity Catalysis of the reaction: UDP-glucose + D-glucose-6-phosphate = UDP + alpha,alpha-trehalose-6-phosphate. GO:0003824 catalytic activity biolink:MolecularActivity go-plus goslim_flybase_ribbon|goslim_chembl|goslim_agr|goslim_pir|goslim_plant|goslim_metagenomics http://purl.obolibrary.org/obo/GO_0003824 Wikipedia:Enzyme enzyme activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003827 RHEA:11456|Reactome:R-HSA-964768|KEGG_REACTION:R05983|MetaCyc:2.4.1.101-RXN|EC:2.4.1.101 GNTI activity|alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:3-(alpha-D-mannosyl)-beta-D-mannosyl-glycoprotein 2-beta-N-acetyl-D-glucosaminyltransferase activity|alpha-1,3-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity|UDP-N-acetylglucosaminyl:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I activity|uridine diphosphoacetylglucosamine-alpha-1,3-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity|GnTI|N-acetylglucosaminyltransferase I activity|alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase activity|UDP-N-acetylglucosaminyl:alpha-1,3-D-mannoside-beta-1,2-N-acetylglucosaminyltransferase I activity|N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I activity Catalysis of the reaction: 3-(alpha-D-mannosyl)-beta-D-mannosyl-R + UDP-N-acetyl-alpha-D-glucosamine = 3-(2-[N-acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R + H(+) + UDP. CHEBI:88090 (7Z)-3-oxohexadecenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88090 GO:0003826 alpha-ketoacid dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003826 Catalysis of an oxidation-reduction (redox) reaction involving an alpha-ketoacid. CHEBI:29739 5alpha,9beta,10alpha-labda-8(20),13-dien-15-yl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29739 GO:0062170 lutein metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062170 lutein metabolism The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform lutein. GO:0062172 lutein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062172 lutein catabolism|lutein degradation|lutein breakdown The chemical reactions and pathways resulting in the breakdown of lutein. GO:0062171 lutein biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062171 lutein formation|lutein biosynthesis|lutein anabolism The chemical reactions and pathways resulting in the formation of lutein. GO:0062174 brexanolone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062174 allotetrahydroprogesterone biosynthesis|allotetrahydroprogesterone biosynthetic process|brexanolone biosynthesis|allotetrahydroprogesterone anabolism|brexanolone anabolism|allotetrahydroprogesterone synthesis|brexanolone synthesis|allopregnanolone biosynthetic process|allopregnanolone biosynthesis|allopregnanolone anabolism|allopregnanolone synthesis The chemical reactions and pathways resulting in the formation of brexanolone. GO:1904359 regulation of spore germination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904359 modulation of spore germination on or near host Any process that modulates the frequency, rate or extent of spore germination. GO:0062173 brexanolone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062173 allotetrahydroprogesterone metabolism|brexanolone metabolism|allopregnanolone metabolism|allopregnanolone metabolic process|allotetrahydroprogesterone metabolic process The chemical reactions and pathways by which living organisms transform brexanolone. GO:0062176 R-loop disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062176 A DNA metabolic process that results in the disassembly of R-loops. R-loops are three-stranded nucleic acid structures consisitng of an RNA:DNA heteroduplex and a looped-out non-template strand. Aberrant formation and persistence of R-loops block transcription elongation and cause DNA damage. Mechanisms that resolve R-loops are essential for genome stability. GO:1904358 positive regulation of telomere maintenance via telomere lengthening biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904358 upregulation of telomere maintenance via telomere lengthening|up regulation of telomere maintenance via telomere lengthening|activation of telomere maintenance via telomere lengthening|up-regulation of telomere maintenance via telomere lengthening Any process that activates or increases the frequency, rate or extent of telomere maintenance via telomere lengthening. GO:0062175 brexanolone catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062175 allopregnanolone catabolism|allopregnanolone degradation|allopregnanolone breakdown|allotetrahydroprogesterone degradation|brexanolone degradation|allopregnanolone catabolic process|brexanolone breakdown|allotetrahydroprogesterone breakdown|brexanolone catabolism|allotetrahydroprogesterone catabolic process|allotetrahydroprogesterone catabolism The chemical reactions and pathways resulting in the breakdown of brexanolone. GO:1904357 negative regulation of telomere maintenance via telomere lengthening biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904357 down regulation of telomere maintenance via telomere lengthening|downregulation of telomere maintenance via telomere lengthening|down-regulation of telomere maintenance via telomere lengthening|inhibition of telomere maintenance via telomere lengthening Any process that stops, prevents or reduces the frequency, rate or extent of telomere maintenance via telomere lengthening. GO:1904356 regulation of telomere maintenance via telomere lengthening biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904356 Any process that modulates the frequency, rate or extent of telomere maintenance via telomere lengthening. GO:0062178 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0062178 GO:1904355 positive regulation of telomere capping biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904355 activation of telomere end protection|positive regulation of telomere end protection|up regulation of telomere capping|up-regulation of telomere end protection|upregulation of telomere end protection|upregulation of telomere capping|up-regulation of telomere capping|up regulation of telomere end protection|activation of telomere capping Any process that activates or increases the frequency, rate or extent of telomere capping. GO:0062177 radial spoke assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062177 The aggregation, arrangement and bonding together of a set of components to form the radial spoke, a protein complex that links the outer microtubule doublet of the ciliary or flagellum axoneme with the sheath that surrounds the central pair of microtubules. GO:1904365 regulation of chemokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904365 Any process that modulates the frequency, rate or extent of chemokinesis. GO:1904364 positive regulation of calcitonin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904364 up regulation of calcitonin secretion|upregulation of calcitonin secretion|up-regulation of calcitonin secretion|activation of calcitonin secretion Any process that activates or increases the frequency, rate or extent of calcitonin secretion. GO:0062179 vitamin D 23-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062179 Catalysis of the hydroxylation of C-23 of any form of vitamin D. GO:1904363 negative regulation of calcitonin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904363 downregulation of calcitonin secretion|down regulation of calcitonin secretion|inhibition of calcitonin secretion|down-regulation of calcitonin secretion Any process that stops, prevents or reduces the frequency, rate or extent of calcitonin secretion. GO:1904362 regulation of calcitonin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904362 Any process that modulates the frequency, rate or extent of calcitonin secretion. GO:1904361 positive regulation of spore germination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904361 upregulation of spore germination|up regulation of spore germination|activation of spore germination|positive regulation of spore germination on or near host|up-regulation of spore germination Any process that activates or increases the frequency, rate or extent of spore germination. GO:1904360 negative regulation of spore germination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904360 down regulation of spore germination|downregulation of spore germination|down-regulation of spore germination|inhibition of spore germination|negative regulation of spore germination on or near host Any process that stops, prevents or reduces the frequency, rate or extent of spore germination. CHEBI:29749 ferulate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29749 CHEBI:30737 trichloromethyl(.) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30737 CHEBI:29748 chorismate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29748 GO:0003801 obsolete blood coagulation factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003801 blood coagulation factor activity OBSOLETE. (Was not defined before being made obsolete). GO:0003800 obsolete antiviral response protein activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003800 antiviral response protein activity OBSOLETE. A protein involved in an antiviral response. CHEBI:29745 barbiturate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29745 CHEBI:29744 lithocholate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29744 CHEBI:29747 cholate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29747 CHEBI:29746 glycocholate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29746 GO:0062161 regulation of pyocyanine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062161 regulation of pyocyanin biosynthetic process Any process that modulates the frequency, rate or extent of a pyocyanine biosynthetic process. GO:0062160 spongiome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062160 A cellular anatomical entity which is a network of tubules and vessicles and is part of the contractile vacuole complex. It is involved in the discharge of water externally. One of its functions is osmoregulatory. GO:0062163 pseudohyphal septin ring assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062163 The aggregation, arrangement and bonding together of septins and associated proteins to form a tight ring-shaped structure that forms in the division plane at the junction between the mother cell and a pseudohyphal projection. CHEBI:29743 3-oxododecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29743 GO:0062162 positive regulation of pyocyanine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062162 positive regulation of pyocyanin biosynthetic process Any process that increases the frequency, rate or extent of a pyocyanine biosynthetic process. GO:0062165 positive regulation of pseudohyphal septin ring assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062165 Any process that increases the rate, frequency or extent of pseudohyphal septin ring formation. GO:1904369 positive regulation of sclerenchyma cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904369 up-regulation of sclerenchyma cell differentiation|upregulation of sclerenchyma cell differentiation|up regulation of sclerenchyma cell differentiation Any process that activates or increases the frequency, rate or extent of sclerenchyma cell differentiation. GO:1904368 regulation of sclerenchyma cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904368 Any process that modulates the frequency, rate or extent of sclerenchyma cell differentiation. GO:0062164 regulation of pseudohyphal septin ring assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062164 Any process that modulates the rate, frequency or extent of pseudohyphal septin ring assembly. GO:1904367 positive regulation of chemokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904367 upregulation of chemokinesis|up-regulation of chemokinesis|activation of chemokinesis|up regulation of chemokinesis Any process that activates or increases the frequency, rate or extent of chemokinesis. GO:0062167 complement component C1q complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062167 C1q|Complement 1q A protein-containing complex composed of six subunits of each of the three homologous polypeptide chains C1QA, C1QB, and C1QB. It is a subunit of the complement C1 complex. In addition to complement activation, C1q appears to have roles in homeostasis and cellular development, superoxide (O2-) production by neutrophils, blood coagulation and neurological synapse pruning. GO:1904366 negative regulation of chemokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904366 inhibition of chemokinesis|down-regulation of chemokinesis|downregulation of chemokinesis|down regulation of chemokinesis Any process that stops, prevents or reduces the frequency, rate or extent of chemokinesis. GO:0062166 negative regulation of pseudohyphal septin ring assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062166 Any process that decreases the rate, frequency or extent of pseudohyphal septin ring assembly. GO:1904376 negative regulation of protein localization to cell periphery biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904376 down-regulation of protein localization to cell periphery|downregulation of protein localization to cell periphery|down regulation of protein localization to cell periphery|inhibition of protein localization to cell periphery Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell periphery. GO:0062169 regulation of plus-end directed microtubule sliding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062169 Any process that mediates the frequency, rate, or extent of plus-end directed microtubule sliding. GO:0062168 negative regulation of plus-end directed microtubule sliding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062168 Any process that stops, prevents, or reduces the frequency, rate, or extent of plus-end directed microtubule sliding. GO:1904375 regulation of protein localization to cell periphery biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904375 Any process that modulates the frequency, rate or extent of protein localization to cell periphery. GO:1904374 cellular response to kainic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904374 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a kainic acid stimulus. GO:1904373 response to kainic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904373 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a kainic acid stimulus. GO:1904372 positive regulation of protein localization to actin cortical patch biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904372 positive regulation of protein localisation to actin cortical patch|up regulation of protein localisation to actin cortical patch|up regulation of protein localization to actin cortical patch|upregulation of protein localisation to actin cortical patch|upregulation of protein localization to actin cortical patch|up-regulation of protein localisation to actin cortical patch|activation of protein localisation to actin cortical patch|up-regulation of protein localization to actin cortical patch|activation of protein localization to actin cortical patch Any process that activates or increases the frequency, rate or extent of protein localization to actin cortical patch. GO:1904371 negative regulation of protein localization to actin cortical patch biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904371 down-regulation of protein localization to actin cortical patch|downregulation of protein localisation to actin cortical patch|down regulation of protein localisation to actin cortical patch|inhibition of protein localisation to actin cortical patch|downregulation of protein localization to actin cortical patch|down regulation of protein localization to actin cortical patch|inhibition of protein localization to actin cortical patch|negative regulation of protein localisation to actin cortical patch|down-regulation of protein localisation to actin cortical patch Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to actin cortical patch. GO:1904370 regulation of protein localization to actin cortical patch biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904370 regulation of protein localisation to actin cortical patch Any process that modulates the frequency, rate or extent of protein localization to actin cortical patch. GO:0003807 obsolete plasma kallikrein activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003807 plasma kallikrein activity|glumorin|panceatic kallikrein|onokrein P|urokallikrein|padreatin|depot-padutin|dilminal D|kallikrein I|serum kallikrein activity|kininogenase|padutin|kallidinogenase|kininogenin activity|kallikrein|kallikrein II|callicrein|urinary kallikrein OBSOLETE. Catalysis of the selective cleavage of Arg-Xaa and Lys-Xaa bonds, including Lys-Arg and Arg-Ser bonds in (human) kininogen to release bradykinin. GO:0003806 obsolete coagulation factor XIIa activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003806 prealbumin activator|kallikreinogen activator|hageman factor activity|blood-coagulation factor XIIabeta|hageman factor beta-fragment|blood-coagulation factor XIIf|blood coagulation factor XII activity|activated beta blood-coagulation factor XII|coagulation factor XIIa activity|hageman factor fragment HFf|hageman factor (activated)|prekallikrein activator OBSOLETE. Catalysis of the selective cleavage of Arg-Ile bonds in factor VII to form factor VIIa and factor XI to form factor XIa. GO:0003809 obsolete thrombin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003809 tropostasin|beta-thrombin|E thrombin|thrombase activity|thrombin-C|activated blood-coagulation factor II|topical|blood-coagulation factor IIa|fibrinogenase activity|thrombofort|gamma-thrombin|factor IIa|thrombin activity OBSOLETE. Catalysis of the preferential cleavage of Arg-Gly; activates fibrinogen to fibrin and releases fibrinopeptide A and B. GO:0003808 obsolete protein C (activated) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003808 GSAPC|blood-coagulation factor XIVa|autoprothrombin IIA activity|protein Ca|activated protein C|activated blood coagulation factor XIV activity|protein C (activated) activity|autoprothrombin II-A OBSOLETE. Catalysis of the degradation of blood coagulation factors Va and VIIIa. GO:0003803 obsolete coagulation factor IXa activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003803 Christmas factor activity|coagulation factor IXa activity|activated christmas factor|activated blood coagulation factor XI|autoprothrombin II|blood platelet cofactor II|blood coagulation factor IX activity|activated blood-coagulation factor IX|blood-coagulation factor IXa OBSOLETE. Catalysis of the selective cleavage of the Arg-Ile bond in factor X to form factor Xa. GO:0003802 obsolete coagulation factor VIIa activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003802 blood coagulation factor VII activity|blood-coagulation factor VIIa|activated blood coagulation factor VII|coagulation factor VIIa activity OBSOLETE. Catalysis of the selective cleavage of one Arg-Ile bond in factor X to form factor Xa, and on factor IX to form factor IXa beta. GO:0003805 obsolete coagulation factor XIa activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003805 blood-coagulation factor XIa|coagulation factor XIa activity|activated plasma thromboplastin antecedent|blood coagulation factor XI activity|activated blood-coagulation factor XI|plasma thromboplastin antecedent activity OBSOLETE. Catalysis of the selective cleavage of Arg-Ala and Arg-Val bonds in factor IX to form factor IXa. GO:0003804 obsolete coagulation factor Xa activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003804 thrombokinase activity|thromboplastin|plasma thromboplastin|Stuart factor|activated blood-coagulation factor X|factor Xa|activated factor X|prothrombinase activity|blood coagulation factor X activity|Stuart factor activity|prothrombase activity|coagulation factor Xa activity|autoprothrombin C|activated Stuart-Prower factor OBSOLETE. Catalysis of the preferential cleavage of Arg-Thr and then Arg-Ile bonds in prothrombin to form thrombin, and on factor VII, which it converts to a two-chain form (factor VIIa). CHEBI:29715 dTDP 1-ester with (6R)-5,6-dihydro-4-hydroxy-6-methyl-5-oxo-2H-pyran biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29715 GO:0062192 L-rhamnose mutarotase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062192 EC:5.1.3.32|RHEA:25584 Catalysis of the reaction: alpha-L-rhamnose = beta-L-rhamnose. GO:0062191 galactoxylomannan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062191 galactoxylomannan anabolism|glucuronoxylomannogalactan biosynthetic process|galactoxylomannan synthesis|GalXM biosynthetic process|galactoxylomannan formation|galactoxylomannan biosynthesis The chemical reactions and pathways resulting in the formation of the exopolysaccharide galactoxylomannan. Galactoxylomannan is produced by a pathogenic fungus and causes paralysis in some animals. GO:0062194 cytoplasmic microtubule minus-end biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062194 A microtubule minus end that is part of a cytoplasmic microtubule. GO:0062193 D-ribose pyranase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062193 RHEA:25432|EC:5.4.99.62 Catalysis of the reaction: beta-D-ribopyranose = beta-D-ribofuranose. GO:0062196 regulation of lysosome size biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062196 Any process that modulates the size of a lysosome. GO:0062195 microtubule bundle maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062195 The organization process that preserves a microtubule bundle in a stable functional or structural state. GO:0062198 obsolete rDNA replication pause site heterochromatin biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062198 OBSOLETE. A region of heterochromatin associated with sites in rDNA repeats where replication forks pause. GO:1904379 protein localization to cytosolic proteasome complex involved in ERAD pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904379 protein localisation to cytosolic proteasome complex involved in endoplasmic reticulum-associated protein degradation pathway|protein localization to cytosolic proteasome complex involved in endoplasmic reticulum-associated degradation|protein localisation to cytosolic proteasome complex involved in ER-associated degradation pathway|protein localization in cytosolic proteasome complex involved in ERAD pathway|protein localisation to cytosolic proteasome complex involved in endoplasmic reticulum-associated degradation|protein localization to cytosolic proteasome complex involved in ER-associated degradation pathway|protein localisation in cytosolic proteasome complex involved in ERAD pathway|protein localisation in cytosolic proteasome complex involved in ER-associated degradation pathway|protein localization in cytosolic proteasome complex involved in endoplasmic reticulum-associated protein degradation pathway|protein localization in cytosolic proteasome complex involved in ER-associated degradation pathway|protein localisation in cytosolic proteasome complex involved in endoplasmic reticulum-associated protein degradation pathway|protein localization in cytosolic proteasome complex involved in endoplasmic reticulum-associated degradation|protein localisation to cytosolic proteasome complex involved in ERAD pathway|protein localization to cytosolic proteasome complex involved in endoplasmic reticulum-associated protein degradation pathway|protein localisation in cytosolic proteasome complex involved in endoplasmic reticulum-associated degradation Any protein localization to cytosolic proteasome complex that is involved in ERAD pathway. Following their retrotranslocation out of the endoplasmic reticulum, protein substrates must be shuttled to the cytosolic proteasome for degradation. GO:0062197 cellular response to chemical stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062197 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus indicating the organism is under stress. GO:1904378 maintenance of unfolded protein involved in ERAD pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904378 maintenance of unfolded protein during ERAD|maintenance of unfolded protein involved in endoplasmic reticulum-associated protein degradation pathway|chaperone holdase activity|ERAD chaperone-like activity|holdase activity|maintenance of unfolded protein involved in endoplasmic reticulum-associated degradation|maintenance of unfolded protein involved in ER-associated degradation pathway Maintaining an endoplasmic reticulum (ER) protein in an unfolded, soluble state that contributes to its degradation by the cytoplasmic proteasome. Maintaining ER-resident proteins in an unfolded yet soluble state condition after their retro-translocation favors their turnover by the cytosolic proteasome. GO:0062199 chromosome, centromeric inner repeat region biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062199 chromosome, centric outer repeat region The portion of the centromeric region of a chromosome that contains the inner inverted repeat region of a modular centromere and part of the central core surrounding a non-conserved central region. This region is adjacent to the central core, on each chromosome arm. GO:1904377 positive regulation of protein localization to cell periphery biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904377 up regulation of protein localization to cell periphery|upregulation of protein localization to cell periphery|activation of protein localization to cell periphery|up-regulation of protein localization to cell periphery Any process that activates or increases the frequency, rate or extent of protein localization to cell periphery. GO:1904387 cellular response to L-phenylalanine derivative biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904387 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-phenylalanine derivative stimulus. GO:1904386 response to L-phenylalanine derivative biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904386 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-phenylalanine derivative stimulus. GO:1904385 cellular response to angiotensin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904385 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an angiotensin stimulus. Angiotensin is any of three physiologically active peptides (angiotensin II, III, or IV) processed from angiotensinogen. GO:1904384 cellular response to sodium phosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904384 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium phosphate stimulus. GO:1904383 response to sodium phosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904383 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium phosphate stimulus. GO:1904382 mannose trimming involved in glycoprotein ERAD pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904382 glycoprotein mannose trimming involved in gpERAD|glycoprotein mannose trimming involved in glycoprotein ERAD|protein alpha-1,2-demannosylation involved in ER-associated glycoprotein degradation|protein alpha-1,2-demannosylation involved in glycoprotein ERAD pathway|glycoprotein mannose trimming involved in ER-associated glycoprotein degradation|glycoprotein mannose trimming involved in glycoprotein ERAD pathway|protein alpha-1,2-demannosylation involved in gpERAD|mannose trimming involved in misfolded or incompletely synthesized glycoprotein catabolic process|protein alpha-1,2-demannosylation involved in glycoprotein ERAD The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein that occurs as part of glycoprotein ER-associated glycoprotein degradation (gpERAD). GO:1904381 Golgi apparatus mannose trimming biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904381 glycoprotein mannose trimming in Golgi complex|glycoprotein mannose trimming in Golgi ribbon|protein alpha-1,2-demannosylation in Golgi apparatus|mannose trimming in cis-Golgi|glycoprotein mannose trimming in Golgi apparatus|mannose trimming in Golgi apparatus|protein alpha-1,2-demannosylation in Golgi ribbon|mannose trimming in Golgi|protein alpha-1,2-demannosylation in Golgi complex Any protein alpha-1,2-demannosylation that takes place in the Golgi apparatus. GO:1904380 endoplasmic reticulum mannose trimming biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904380 protein alpha-1,2-demannosylation in ER|protein alpha-1,2-demannosylation in endoplasmic reticulum|protein alpha-1,2-demannosylation in ER-derived quality control compartment|glycoprotein mannose trimming in ER-derived quality control compartment|protein alpha-1,2-demannosylation in ERQC|protein alpha-1,2-demannosylation in ER quality control compartment|glycoprotein mannose trimming in ERQC|ER mannose trimming|protein alpha-1,2-demannosylation in endoplasmic reticulum quality control compartment|glycoprotein mannose trimming in ER quality control compartment|glycoprotein mannose trimming in endoplasmic reticulum quality control compartment|ER protein alpha-1,2-demannosylation Any protein alpha-1,2-demannosylation that takes place in the endoplasmic reticulum quality control compartment (ERQC). CHEBI:29726 dTDP-6-deoxy-alpha-D-allose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29726 CHEBI:29728 dTDP-alpha-D-mycaminose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29728 GO:0062181 1-alpha,25-dihydroxyvitamin D3 23-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062181 RHEA:49192 Catatlysis of the reaction: calcitriol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = 1alpha,23S,25-trihydroxycholecalciferol + H2O + 2 oxidized [adrenodoxin]. GO:0062180 25-hydroxycholecalciferol-23-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062180 RHEA:46616 Catalysis of the reaction: calcidiol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = (23S)-23,25-dihydroxycalciol + H2O + 2 oxidized [adrenodoxin]. CHEBI:425902 propiophenone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_425902 GO:0062183 all-trans retinoic acid 18-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062183 RHEA:55856 Catalysis of the reaction: all-trans-retinoate + O2 + reduced [NADPH--hemoprotein reductase] = all-trans-18-hydroxyretinoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]. GO:0062182 all-trans retinoic acid 4-hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062182 RHEA:51492 Catalysis of the reaction: all-trans-retinoate + O2 + reduced [NADPH--hemoprotein reductase] = all-trans-(4S)-hydroxyretinoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]. GO:0062185 secalciferol 1-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062185 RHEA:49064 Catalysis of the reaction:2 H(+) + O2 + 2 reduced [adrenodoxin] + secalciferol = calcitetrol + H2O + 2 oxidized [adrenodoxin]. GO:0062184 testosterone 16-beta-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062184 RHEA:46304 Catalysis of the reaction: O2 + reduced [NADPH--hemoprotein reductase] + testosterone = 16beta,17beta-dihydroxyandrost-4-en-3-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]. GO:0062187 anandamide 8,9 epoxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062187 RHEA:53140 Catalysis of the reaction: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + N-(8,9-epoxy-5Z,11Z,14Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase]. CHEBI:30719 citraconate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30719 GO:0062186 anandamide epoxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062186 arachidonoylethanolamide epoxidase activity Catalysis of the epoxidation of double bonds of the arachidonoyl moiety of anandamide. GO:1904389 rod bipolar cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904389 The process in which a relatively unspecialized cell acquires the specialized features of a rod bipolar cell. GO:0062189 anandamide 14,15 epoxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062189 RHEA:53148 Catalysis of the reaction: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + N-(14,15-epoxy-5Z,8Z,11Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase]. GO:1904388 negative regulation of ncRNA transcription associated with protein coding gene TSS/TES biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904388 inhibition of ncRNA transcription associated with protein coding gene TSS/TES|downregulation of pasRNA transcription|down regulation of pasRNA transcription|down regulation of ncRNA transcription associated with protein coding gene TSS/TES|inhibition of pasRNA transcription|downregulation of ncRNA transcription associated with protein coding gene TSS/TES|down-regulation of ncRNA transcription associated with protein coding gene TSS/TES|down-regulation of pasRNA transcription|negative regulation of pasRNA transcription Any process that stops, prevents or reduces the frequency, rate or extent of ncRNA transcription associated with protein coding gene TSS/TES. GO:0062188 anandamide 11,12 epoxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062188 RHEA:53144 Catalysis of the reaction: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + N-(11,12-epoxy-5Z,8Z,14Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase]. GO:1904398 positive regulation of neuromuscular junction development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904398 activation of neuromuscular junction organization|positive regulation of neuromuscular junction organization|activation of neuromuscular junction stability|up-regulation of neuromuscular junction development|activation of neuromuscular junction development|up regulation of NMJ stability|positive regulation of neuromuscular junction stability|up-regulation of neuromuscular junction organization|up regulation of neuromuscular junction stability|positive regulation of NMJ stability|activation of NMJ stability|upregulation of neuromuscular junction organization|up regulation of neuromuscular junction development|upregulation of neuromuscular junction stability|up-regulation of NMJ stability|up regulation of neuromuscular junction organization|upregulation of neuromuscular junction development|up-regulation of neuromuscular junction stability|upregulation of NMJ stability Any process that activates or increases the frequency, rate or extent of neuromuscular junction development. GO:1904397 negative regulation of neuromuscular junction development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904397 down regulation of NMJ stability|negative regulation of neuromuscular junction organization|down-regulation of neuromuscular junction organization|down-regulation of neuromuscular junction stability|negative regulation of neuromuscular junction stability|downregulation of NMJ stability|inhibition of neuromuscular junction organization|downregulation of neuromuscular junction stability|down-regulation of neuromuscular junction development|down-regulation of NMJ stability|negative regulation of NMJ stability|down regulation of neuromuscular junction stability|downregulation of neuromuscular junction development|down regulation of neuromuscular junction organization|inhibition of neuromuscular junction stability|inhibition of NMJ stability|down regulation of neuromuscular junction development|downregulation of neuromuscular junction organization|inhibition of neuromuscular junction development Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular junction development. GO:1904396 regulation of neuromuscular junction development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904396 regulation of NMJ stability|regulation of neuromuscular junction stability|regulation of neuromuscular junction organization Any process that modulates the frequency, rate or extent of neuromuscular junction development. GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904395 up regulation of skeletal muscle acetylcholine-gated channel clustering|up regulation of skeletal muscle AChR clustering|upregulation of skeletal muscle nicotinic acetylcholine receptor clustering|activation of skeletal muscle AChR clustering|positive regulation of skeletal muscle AChR clustering|upregulation of skeletal muscle acetylcholine-gated channel clustering|up regulation of skeletal muscle nicotinic acetylcholine receptor clustering|activation of skeletal muscle nicotinic acetylcholine receptor clustering|positive regulation of skeletal muscle nicotinic acetylcholine receptor clustering|up-regulation of skeletal muscle AChR clustering|activation of skeletal muscle acetylcholine-gated channel clustering|up-regulation of skeletal muscle acetylcholine-gated channel clustering|upregulation of skeletal muscle AChR clustering|up-regulation of skeletal muscle nicotinic acetylcholine receptor clustering Any process that activates or increases the frequency, rate or extent of skeletal muscle acetylcholine-gated channel clustering. GO:1904394 negative regulation of skeletal muscle acetylcholine-gated channel clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904394 downregulation of skeletal muscle acetylcholine-gated channel clustering|down regulation of skeletal muscle nicotinic acetylcholine receptor clustering|down regulation of skeletal muscle acetylcholine-gated channel clustering|down-regulation of skeletal muscle AChR clustering|inhibition of skeletal muscle acetylcholine-gated channel clustering|negative regulation of skeletal muscle AChR clustering|downregulation of skeletal muscle nicotinic acetylcholine receptor clustering|inhibition of skeletal muscle AChR clustering|down-regulation of skeletal muscle nicotinic acetylcholine receptor clustering|negative regulation of skeletal muscle nicotinic acetylcholine receptor clustering|inhibition of skeletal muscle nicotinic acetylcholine receptor clustering|down-regulation of skeletal muscle acetylcholine-gated channel clustering|down regulation of skeletal muscle AChR clustering|downregulation of skeletal muscle AChR clustering Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle acetylcholine-gated channel clustering. GO:1904393 regulation of skeletal muscle acetylcholine-gated channel clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904393 regulation of skeletal muscle nicotinic acetylcholine receptor clustering|regulation of skeletal muscle AChR clustering Any process that modulates the frequency, rate or extent of skeletal muscle acetylcholine-gated channel clustering. GO:1904392 cellular response to ciliary neurotrophic factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904392 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ciliary neurotrophic factor stimulus. GO:1904391 response to ciliary neurotrophic factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904391 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ciliary neurotrophic factor stimulus. GO:1904390 cone retinal bipolar cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904390 cone bipolar cell differentiation|retinal cone bipolar cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a cone retinal bipolar cell. CHEBI:8588 protodioscin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_8588 GO:0052722 fatty acid in-chain hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052722 RHEA:45084|MetaCyc:RXN-12186 Catalysis of the reaction: fatty acid + O2 + 2 NADPH + H+ = fatty acid with in-chain hydroxy group + 2 NADP+ + H2O. GO:0003799 obsolete antifungal peptide activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003799 antifungal peptide activity OBSOLETE. Inhibits the growth of, or directly kills, fungal cells. GO:0003798 obsolete male-specific antibacterial peptide activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003798 male-specific antibacterial peptide activity OBSOLETE. Inhibits the growth of, or directly kills, bacterial cells, but which is only expressed in males. GO:0052721 regulation of apurinic/apyrimidinic endodeoxyribonuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052721 regulation of apyrimidinic endodeoxyribonuclease activity|regulation of apurinic endodeoxyribonuclease activity|regulation of abasic endodeoxyribonuclease activity|regulation of AP endodeoxyribonuclease activity Any process that modulates the frequency, rate or extent of apurinic/apyrimidinic (AP) endodeoxyribonuclease activity, the hydrolysis of ester linkages immediately 5' to an AP (also called abasic) site within a deoxyribonucleic acid molecule by creating internal breaks, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. GO:0052720 class II DNA-(apurinic or apyrimidinic site) endonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052720 class II DNA-(apurinic or apyrimidinic site) lyase activity Catalysis of the hydrolysis of ester linkages immediately 5' to an apurinic/apyrimidinic (AP; also called abasic) site within a deoxyribonucleic acid molecule by creating internal breaks, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. GO:0052726 inositol-1,3,4-trisphosphate 5-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052726 RHEA:13253|Reactome:R-HSA-994140|Reactome:R-HSA-1855172|KEGG_REACTION:R03428|MetaCyc:2.7.1.139-RXN|EC:2.7.1.159 ins(1,3,4)P(3) 5-kinase activity|1D-myo-inositol-trisphosphate 5-kinase activity|inositol-trisphosphate 5-kinase activity|ATP:1D-myo-inositol-1,3,4-trisphosphate 5-phosphotransferase activity|Ins(1,3,4)P3 5-kinase activity|IP3 5-kinase activity|inositol 1,3,4-trisphosphate 5-kinase activity Catalysis of the reaction: 1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + 2 H(+). GO:0003795 obsolete antimicrobial peptide activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003795 antimicrobial peptide activity OBSOLETE. Inhibits the growth of, or directly kills, microbial cells. GO:0052725 inositol-1,3,4-trisphosphate 6-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052725 Reactome:R-HSA-1855197|Reactome:R-HSA-2267372|RHEA:20940|MetaCyc:2.7.1.133-RXN|EC:2.7.1.159 1D-myo-inositol-trisphosphate 6-kinase activity|inositol-trisphosphate 6-kinase activity|ATP:1D-myo-inositol-1,3,4-trisphosphate 6-phosphotransferase activity|Ins(1,3,4)P3 6-kinase activity|IP3 6-kinase activity|inositol 1,3,4-trisphosphate 6-kinase activity|ins(1,3,4)P(3) 6-kinase activity Catalysis of the reaction: 1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ADP + 2 H(+). GO:0003794 obsolete acute-phase response protein activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003794 acute-phase response protein activity OBSOLETE. (Was not defined before being made obsolete). GO:0052724 inositol hexakisphosphate 3-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052724 MetaCyc:RXN-10971|EC:2.7.4.21 Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 3-diphospho-1D-myo-inositol (1,2,4,5,6)pentakisphosphate. GO:0003797 obsolete antibacterial peptide activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003797 antibacterial peptide activity OBSOLETE. Inhibits the growth of, or directly kills, bacterial cells. GO:0052723 inositol hexakisphosphate 1-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052723 MetaCyc:RXN-10972|RHEA:37459|KEGG_REACTION:R05799|EC:2.7.4.21 Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 1-diphospho-1D-myo-inositol (2,3,4,5,6)pentakisphosphate. GO:0003796 lysozyme activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003796 MetaCyc:3.2.1.17-RXN|Reactome:R-HSA-8862320|EC:3.2.1.17 mucopeptide N-acetylmuramoylhydrolase activity|N,O-diacetylmuramidase activity|peptidoglycan N-acetylmuramoylhydrolase activity|lysozyme g|1,4-N-acetylmuramidase activity|PR1-lysozyme|globulin G|L-7001|mucopeptide glucohydrolase activity|globulin G1|muramidase activity Catalysis of the hydrolysis of the beta-(1->4) linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan. GO:0003791 obsolete membrane associated actin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003791 membrane associated actin binding OBSOLETE. (Was not defined before being made obsolete). CHEBI:64023 1-palmitoylglycerol 3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64023 GO:0052729 dimethylglycine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052729 MetaCyc:R482-RXN|KEGG_REACTION:R07244|RHEA:10072|EC:2.1.1.157|EC:2.1.1.162|EC:2.1.1.161|MetaCyc:RXN-9680 ApDMT|S-adenosyl-L-methionine:N,N-dimethylglycine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + N,N-dimethylglycine = S-adenosyl-L-homocysteine + betaine. GO:0003790 obsolete actin modulating activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003790 actin modulating activity OBSOLETE. (Was not defined before being made obsolete). GO:0003793 obsolete defense/immunity protein activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003793 defence/immunity protein activity|defense/immunity protein activity OBSOLETE. Any activity that plays a role in the defense/immune response of an organism against infection and disease. GO:0052728 capsorubin synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052728 MetaCyc:RXN-7946|EC:5.3.99.8|RHEA:21752 CCS|capsanthin-capsorubin synthase activity|ketoxanthophyll synthase activity|violaxanthin-capsorubin isomerase (ketone-forming) activity Catalysis of the reaction: violaxanthin = capsorubin. GO:0003792 obsolete regulation of actin thin filament length activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003792 regulation of actin thin filament length activity OBSOLETE. (Was not defined before being made obsolete). GO:0052727 capsanthin synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052727 RHEA:17373|MetaCyc:RXN-7947|EC:5.3.99.8 CCS|capsanthin-capsorubin synthase activity|ketoxanthophyll synthase activity Catalysis of the reaction: antheraxanthin = capsanthin. CHEBI:64024 beta-D-GlcpA-(1->3)-D-GlcpNAc biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64024 CHEBI:78664 (5Z,11Z,14Z,17Z)-icosatetraenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78664 CHEBI:39056 nitrilotriacetate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39056 CHEBI:39055 2,2'-[(carboxymethyl)imino]diacetate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39055 CHEBI:78663 (5Z,11Z,14Z)-icosatrienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78663 CHEBI:39054 NTA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39054 CHEBI:78662 2,3-epoxysqualene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78662 CHEBI:39053 nitrilotriacetate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39053 CHEBI:78666 5beta-pregnan-20alpha-ol-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78666 CHEBI:39057 2,2',2''-ammoniotriacetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_39057 GO:0052733 quinate 3-dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052733 KEGG_REACTION:R06846|RHEA:18425|EC:1.1.1.282 quinate:NADP(+) 3-oxidoreductase activity|quinic dehydrogenase activity|quinate:NADP 3-oxidoreductase activity Catalysis of the reaction: quinate + NADP+ = 3-dehydroquinate + NADPH + H+. GO:0052732 phosphoethanolamine phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052732 EC:3.1.3.75|KEGG_REACTION:R06870|RHEA:16089|Reactome:R-HSA-1483096|MetaCyc:RXN-7948 phosphoethanolamine phosphohydrolase activity|3X11A|PHOSPHO1 Catalysis of the reaction: O-phosphoethanolamine + H2O = ethanolamine + phosphate. GO:0052731 phosphocholine phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052731 EC:3.1.3.75|Reactome:R-HSA-1483159|KEGG_REACTION:R06871|RHEA:10492|MetaCyc:RXN-5647 phosphoethanolamine phosphohydrolase activity|3X11A|PHOSPHO1 Catalysis of the reaction: choline phosphate + H2O = choline + phosphate. GO:0052730 sarcosine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052730 MetaCyc:RXN-7042|MetaCyc:R481-RXN|RHEA:15453|KEGG_REACTION:R07243|EC:2.1.1.157|EC:2.1.1.156|EC:2.1.1.162|MetaCyc:RXN-9679 SDMT|S-adenosyl-L-methionine:N,N-sarcosine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine + N,N-dimethylglycine. GO:0052737 pyruvate dehydrogenase (quinone) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052737 RHEA:27405|KEGG_REACTION:R03145|EC:1.2.5.1|MetaCyc:RXN-11496 pyruvate:ubiquinone-8-oxidoreductase activity|pyruvate:ubiquinone oxidoreductase activity|pyruvic dehydrogenase activity|pyruvate dehydrogenase activity Catalysis of the reaction: a ubiquinone + H2O + pyruvate = a ubiquinol + acetate + CO2. GO:0052736 beta-glucanase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052736 beta-D-glucanase activity Catalysis of the hydrolysis of linkages in beta-D-glucans; beta-glucans are polysaccharides of D-glucose monomers linked by beta-glycosidic bonds. GO:0052735 tRNA (cytosine-3-)-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052735 S-adenosyl-L-methionine:tRNA (cytosine-3-)-methyltransferase activity|tRNA (cytosine 3)-methyltransferase activity|tRNA cytosine 3-methyltransferase activity|S-adenosyl-L-methionine:tRNA cytosine-3-methyltransferase activity|tRNA cytosine-3-methyltransferase activity|transfer ribonucleate cytosine 3-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 3-methylcytosine. GO:0052734 shikimate 3-dehydrogenase (NAD+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052734 KEGG_REACTION:R06847|RHEA:17741|EC:1.1.1.282 DHS reductase activity|shikimate:NAD(P)(+) 3-oxidoreductase activity|3-dehydroshikimate reductase activity|shikimate oxidoreductase activity|shikimate:NAD(P)(+) oxidoreductase activity|3-dehydroshikimic reductase activity|dehydroshikimic reductase activity Catalysis of the reaction: shikimate + NAD+ = 3-dehydroshikimate + NADH + H+. CHEBI:64033 EC 3.5.1.99 (fatty acid amide hydrolase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64033 GO:0052739 phosphatidylserine 1-acylhydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052739 EC:3.1.1.32|KEGG_REACTION:R04034|Reactome:R-HSA-8869425 phosphatidylserine-specific phospholipase A1 activity Catalysis of the reaction: phosphatidylserine + H2O = 2-acyl-sn-glycero-3-phosphoserine + fatty acid. CHEBI:64032 linoleoyl ethanolamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64032 CHEBI:64031 (3E)-2-oxohex-3-enedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64031 GO:0052738 oxidoreductase activity, acting on the aldehyde or oxo group of donors, with a quinone or similar compound as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052738 EC:1.2.5.- Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a quinone or similar compound. CHEBI:64038 (3Z)-2-oxohex-3-enedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64038 CHEBI:64037 (2E,4Z)-2-hydroxymuconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64037 CHEBI:64039 (2S)-pristanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64039 CHEBI:78670 (8Z,11Z)-icosadienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78670 CHEBI:78675 fundamental metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78675 CHEBI:78679 D-ribose 5-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78679 CHEBI:15076 selenide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15076 CHEBI:15075 selenate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15075 PO:0002003 xylem vessel member biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0002003 miembro de vaso (Spanish, exact)|vessel element (exact)|vessel segment (exact)|木質部道管状要素 (Japanese, exact)|vessel member (exact) A tracheary element (PO:0000290) that is part of a xylem vessel (PO:0025417) and has as parts perforation plates. GO:0003777 microtubule motor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003777 Reactome:R-HSA-177479|Reactome:R-HSA-265160 dynein ATPase activity|dynein|kinesin motor activity|kinesin|axonemal motor activity|kinetochore motor activity Catalysis of movement along a microtubule, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP). GO:0052744 phosphatidylinositol monophosphate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052744 Catalysis of the reaction: phosphatidylinositol monophosphate + H2O = phosphatidylinositol + phosphate. GO:0003776 obsolete muscle motor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003776 muscle motor activity OBSOLETE. (Was not defined before being made obsolete). GO:0052743 inositol tetrakisphosphate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052743 Catalysis of the reaction: myo-inositol tetrakisphosphate + H2O = myo-inositol trisphosphate + phosphate. PO:0002002 embryo basal cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0002002 embryonic basal cell (exact)|célula basal (Spanish, exact)|胚基底細胞 (Japanese, exact) A native plant cell (PO:0025606) that is the lower-most cell formed after the first division of the plant zygote (PO:0000423) and is part of a plant embryo (PO:0009009). GO:0052742 phosphatidylinositol kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052742 Catalysis of the reaction: ATP + a phosphatidylinositol = ADP + a phosphatidylinositol phosphate. GO:0003779 actin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003779 membrane associated actin binding Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments. GO:0052741 (R)-limonene 6-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052741 EC:1.14.14.53|KEGG_REACTION:R06119|RHEA:18957|MetaCyc:1.14.13.84-RXN (+)-limonene-6-hydroxylase activity|(R)-limonene,NADPH:oxygen oxidoreductase (6-hydroxylating) activity|(+)-limonene 6-monooxygenase activity Catalysis of the reaction: (4R)-limonene + H+ + NADPH + O2 = (1R,5S)-carveol + H2O + NADP+. GO:0003778 obsolete dynactin motor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003778 dynactin motor OBSOLETE. (Was not defined before being made obsolete). GO:0052748 baicalin beta-D-glucuronidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052748 EC:3.2.1.167|RHEA:28130|MetaCyc:RXN-11760|KEGG_REACTION:R09533 5,6,7-trihydroxyflavone-7-O-beta-D-glucupyranosiduronate glucuronosylhydrolase activity|baicalinase activity Catalysis of the reaction: baicalin + H2O = baicalein + D-glucuronate. GO:0003773 obsolete heat shock protein activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003773 heat shock protein activity OBSOLETE. Any of a group of specific proteins that are synthesized by both prokaryotic and eukaryotic cells after they have been exposed to a temperature that is higher than normal. Other stresses, e.g. free radical damage, have a similar effect. Many members of the hsp family are not induced but are present in all cells. They are characterized by their role as molecular chaperones. GO:0003772 obsolete co-chaperonin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003772 co-chaperonin activity OBSOLETE. Co-chaperonins are proteins that bind to chaperones and this complex then folds misfolded proteins. Co-chaperonins by themselves do not possess chaperone activity. GO:0052747 sinapyl alcohol dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052747 MetaCyc:RXN-1125|EC:1.1.1.195|KEGG_REACTION:R03918|RHEA:45704 sinapyl-alcohol:NADP+ oxidoreductase activity|sinapyl-alcohol dehydrogenase activity Catalysis of the reaction: sinapaldehyde + NADPH + H+ = sinapyl-alcohol + NADP+. GO:0003775 obsolete axonemal motor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003775 axonemal motor activity OBSOLETE. (Was not defined before being made obsolete). GO:0052746 inositol phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052746 inositol and derivative phosphorylation|myo-inositol and derivative phosphorylation|myo-inositol phosphorylation The process of introducing one or more phosphate groups into inositol. Inositol is the cyclic alcohol 1,2,3,4,5,6-cyclohexanehexol, which is widely distributed in nature and acts as a growth factor in animals and microorganisms. GO:0003774 motor activity biolink:MolecularActivity go-plus goslim_candida|goslim_pir|goslim_plant|goslim_aspergillus http://purl.obolibrary.org/obo/GO_0003774 Reactome:R-HSA-1861595 Catalysis of the generation of force resulting either in movement along a microfilament or microtubule, or in torque resulting in membrane scission, coupled to the hydrolysis of a nucleoside triphosphate. GO:0052745 inositol phosphate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052745 Catalysis of the reaction: inositol phosphate(n) + H2O = inositol phosphate(n-1) + phosphate. This reaction is the removal of a phosphate group from an inositol phosphate. GO:0003771 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003771 CHEBI:40036 amitrole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_40036 GO:0052749 glucose-6-phosphate dehydrogenase (coenzyme F420) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052749 KEGG_REACTION:R09550|RHEA:27294|EC:1.1.98.2|MetaCyc:RXN-11283 coenzyme F420-dependent glucose-6-phosphate dehydrogenase activity|D-glucose-6-phosphate:F420 1-oxidoreductase activity|F420-dependent glucose-6-phosphate dehydrogenase activity Catalysis of the reaction: beta-D-glucose 6-phosphate + coenzyme F420 + H+ = 6-O-phosphono-D-glucono-1,5-lactone + reduced coenzyme F420. GO:0003770 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003770 CHEBI:64049 food acidity regulator biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64049 CHEBI:88015 archaeal dolichol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88015 CHEBI:64047 food additive biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64047 CHEBI:78682 D-fructose 1,6-bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78682 CHEBI:78680 (9Z,12Z)-tetradecadienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78680 CHEBI:78686 Delta(4)-dafachronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78686 CHEBI:78684 (9Z,12Z)-pentadecadienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78684 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052740 EC:3.1.1.32 phosphatidylserine-specific phospholipase A1 activity Catalysis of the reaction: 1-acyl-2-lysophosphatidylserine + H2O = sn-glycerol-phosphoserine + a carboxylate. CHEBI:78688 2,4-diacetylphloroglucinol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78688 CHEBI:78687 D-fructofuranose 2,6-bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78687 GO:0052755 reduced coenzyme F420:quinone oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052755 F420H2:2,3-dimethyl-1,4-naphthoquinone oxidoreductase activity|F420H2-dependent quinone oxidoreductase activity|F420H2:quinone oxidoreductase activity Catalysis of the reaction: reduced coenzyme F420 + 2,3-dimethyl-1,4-naphthoquinone = coenzyme F420 + reduced 2,3-dimethyl-1,4-naphthoquinone. Reduced 2,3-dimethyl-1,4-naphthoquinone is also known as 2,3-dimethyl-1,4-hydronaphthoquinone. GO:0003788 obsolete actin monomer sequestering activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003788 actin monomer sequestering activity OBSOLETE. (Was not defined before being made obsolete). GO:0052754 GTP:coenzyme F420 guanyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052754 GTP:coenzyme F420 guanylyltransferase activity|coenzyme F390-G synthetase activity Catalysis of the reaction: GTP + factor gamma-F420-2 + H+ = coenzyme F390-G + diphosphate. GO:0003787 obsolete actin depolymerizing activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003787 actin depolymerizing activity OBSOLETE. (Was not defined before being made obsolete). GO:0052753 propan-2-ol:coenzyme F420 oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052753 F420-dependent secondary alcohol dehydrogenase activity|F420-dependent propan-2-ol dehydrogenase activity|isopropanol:coenzyme F420 oxidoreductase activity Catalysis of the reaction: propan-2-ol + coenzyme F420 = acetone + reduced coenzyme F420. GO:0052752 reduced coenzyme F420:heterodisulfide oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052752 coenzyme F420-dependent heterodisulfide oxidoreductase activity|F420H2:heterodisulfide oxidoreductase activity|F420-dependent heterodisulfide oxidoreductase activity Catalysis of the reaction: reduced coenzyme F420 + CoB-S-S-CoM = coenzyme F420 + CoM-SH + CoB-SH. GO:0003789 obsolete actin filament severing activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003789 actin filament severing activity OBSOLETE. (Was not defined before being made obsolete). GO:0052759 coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052759 EC:1.3.99.-|UM-BBD_reactionID:r1066 coenzyme F420-dependent 2,4,6-trinitrophenol-hydride-Meisenheimer-complex hydride transferase activity Catalysis of the reaction: trinitrophenol hydride Meisenheimer complex + H- = trinitrophenol dihydride Meisenheimer complex (aci form). Coenzyme F420 supplies the hydride (H-) in the reaction. GO:0003784 obsolete barbed-end actin capping/severing activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003784 barbed-end actin capping/severing activity OBSOLETE. (Was not defined before being made obsolete). GO:0052758 coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052758 EC:1.3.99.-|UM-BBD_reactionID:r1065 TNP reductase activity|coenzyme F420-dependent 2,4,6-trinitrophenol hydride transferase activity Catalysis of the reaction: 2,4,6-trinitrophenol + H- = 2,4,6-trinitrophenol hydride Meisenheimer complex. Coenzyme F420 supplies the hydride (H-) in the reaction. GO:0003783 obsolete barbed-end actin capping activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003783 barbed-end actin capping activity OBSOLETE. (Was not defined before being made obsolete). GO:0052757 chondroitin hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052757 chondroitin endo-beta-galactosaminidase activity Catalysis of the hydrolysis of hexosaminic linkages in chondroitin, a linear polymer structure composed of the repeating disaccharide unit [->4)-D-glucuronic acid-(1->3)-N-acetyl-D-galactosamine-(1-], also written as [->4GlcUA1->3GalNAc1-]. GO:0003786 actin lateral binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003786 Interacting selectively and non-covalently with an actin filament along its length. GO:0052756 chitobiose phosphorylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052756 Catalysis of the reaction: chitobiose + phosphate = N-acetyl-D-glucosamine + N-acetyl-alpha-D-glucosamine 1-phosphate. This reaction is the phosphorolysis of chitobiose, (GlcNAc)2, a dimer of beta-(1->4) linked glucosamine units. GO:0003785 actin monomer binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003785 G actin binding Interacting selectively and non-covalently with monomeric actin, also known as G-actin. GO:0003780 obsolete actin cross-linking activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003780 actin cross-linking activity OBSOLETE. Interacting selectively with two actin filaments to anchor them together. GO:0003782 obsolete F-actin capping activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003782 F-actin capping activity OBSOLETE. (Was not defined before being made obsolete). CHEBI:88003 fructose 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88003 GO:0003781 obsolete actin bundling activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003781 actin bundling activity OBSOLETE. (Was not defined before being made obsolete). CHEBI:88005 3-phosphoglycerate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88005 CHEBI:88004 alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88004 CHEBI:88007 3-oxooleoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88007 CHEBI:88008 (7Z)-hexadecenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88008 CHEBI:78691 EC 2.3.1.97 (glycylpeptide N-tetradecanoyltransferase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78691 CHEBI:78690 (9Z,12Z)-heptadecadienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78690 CHEBI:78697 D-fructose 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78697 GO:0052751 GDP-mannose hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052751 GDP-mannose pyrophosphatase activity Catalysis of the reaction: GDP-mannose + H2O = GMP + mannose-1-phosphate. GO:0052750 reactive-black-5:hydrogen-peroxide oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052750 KEGG_REACTION:R07612|RHEA:22396|EC:1.11.1.16|MetaCyc:RXN-8666 versatile peroxidase activity Catalysis of the reaction: reactive black 5 + hydrogen peroxide = oxidized reactive black 5 + 2 H2O. CHEBI:78699 Delta(7)-dafachronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78699 PO:0002000 stomatal complex biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0002000 stoma (broad)|stomate (exact)|complejo estomático (Spanish, exact)|気孔装置 (Japanese, exact)|stomata (broad)|stomatal apparatus (exact) A portion of shoot system epidermis (PO:0006035) that has as parts two guard cells (PO:0000293) and a stomatal pore (PO:0008032). May also contain subsidiary cells (PO:0000284). CHEBI:78698 dafachronic acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78698 GO:0003755 peptidyl-prolyl cis-trans isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003755 Reactome:R-HSA-2022073|EC:5.2.1.8|RHEA:16237|Reactome:R-HSA-9626816|MetaCyc:PEPTIDYLPROLYL-ISOMERASE-RXN peptidylprolyl cis-trans isomerase activity|peptidyl-prolyl isomerase B reaction|parvulin|juglone-sensitive cis-trans proline isomerase activity|PPIase activity|cis-trans proline isomerase activity|immunophilin|rotamase activity|cyclophilin activity|peptide bond isomerase activity|FK506-sensitive peptidyl-prolyl cis-trans isomerase|cyclophilin-type peptidyl-prolyl cis-trans isomerase activity|peptidylproline cis-trans-isomerase activity|peptidylprolyl isomerase activity|juglone-sensitive peptidyl-prolyl cis-trans isomerase activity Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0). GO:0052766 mannoside alpha-1,4-mannosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052766 alpha-1,4-exomannosidase activity|mannoside alpha-1,4-exomannosidase activity|mannoside exo-alpha-1,4-mannosidase activity|alpha-1,4-mannosidase activity Catalysis of the hydrolysis of the alpha-(1->4) linkage of the terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides. GO:0052765 reduced coenzyme F420 oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052765 F420H2:oxygen oxidoreductase activity|coenzyme F420H2 oxidase activity|F420H2 oxidase activity Catalysis of the reaction: 2 reduced coenzyme F420 + O2 = 2 coenzyme F420 + 2 H2O. GO:0003754 obsolete chaperone activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003754 chaperone activity OBSOLETE. Assists in the correct non-covalent assembly of polypeptide-containing structures in vivo, but is not a component of these assembled structures when they are performing their normal biological function. GO:0052764 exo-oligoalginate lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052764 EC:4.2.2.26 Catalysis of the cleavage of glycosidic bonds through a beta-elimination reaction on alginate, a linear polysaccharide consisting of guluronate (G) and mannuronate (M) as the monomer constituents. An oligoalginate is a linear polymer of two, three or four units of (1->4)-alpha-L-guluronic acid and beta-D-mannuronic acid, releasing monosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends. GO:0003757 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003757 GO:0003756 protein disulfide isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003756 Reactome:R-HSA-8950456|Reactome:R-HSA-8950113|MetaCyc:5.3.4.1-RXN|Reactome:R-HSA-8950183|EC:5.3.4.1 protein thiol-disulfide exchange|protein disulfide-isomerase reaction|disulphide bond formation|protein disulphide isomerase activity|protein cysteine-thiol oxidation|protein thiol-disulphide exchange|protein disulfide-isomerase|disulphide bond biosynthesis|S-S rearrangase activity Catalysis of the rearrangement of both intrachain and interchain disulfide bonds in proteins. GO:0052763 ulvan lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052763 Catalysis of the cleavage of a carbon-oxygen bond in ulvan, a carbohydrate composed of a repeating structure of [->4)-beta-D-GlcA-(1,4)-alpha-L-Rha 3S-(1->4)-alpha-L-IdoA-(1->4)-alpha-L-Rha 3S-(1-]n. Continued digest of ulvan with an enzyme that can catalyze this reaction results in ulvanobiouronic acid A 3-sulfate [->4)-beta-D-GlcpA-(1->4)-alpha-L-Rhap 3-sulfate-(1-]n with 4-deoxy-L-threo-hex-4-enopyranosiduronic acid at the non-reducing end. GO:0003751 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003751 GO:0052769 beta-6-sulfate-N-acetylglucosaminidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052769 beta-6-SO3-N-acetylglucosaminidase activity|sulfomucin beta-6-sulfate-N-acetylglucosaminidase activity|exosulfoglycosidase activity|sulfoglycosidase activity Catalysis of the glycosidic cleavage of the terminal 2-acetamido-2-deoxy-beta-D-glucopyranoside 6-sulfate (6-SO3-GlcNAc) residue from sulfomucin, a sulfated mucin derivative. GO:0003750 obsolete cell cycle regulator biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003750 cell cycle regulator OBSOLETE. (Was not defined before being made obsolete). GO:0052768 mannosyl-oligosaccharide 1,3-alpha-mannosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052768 EC:3.1.1.- 1,3-alpha-mannosyl-oligosaccharide alpha-D-mannohydrolase activity|alpha-1,3-mannosyl-oligosaccharide alpha-D-mannohydrolase activity|1,3-alpha-mannosidase activity|alpha-1,3-mannosidase activity Catalysis of the hydrolysis of the alpha-(1->3) bonds of alpha-D-mannose residues in mannosyl-oligosaccharide. GO:0003753 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003753 GO:0052767 mannosyl-oligosaccharide 1,6-alpha-mannosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052767 EC:3.1.1.- 1,6-alpha-mannosyl-oligosaccharide alpha-D-mannohydrolase activity|alpha-1,6-mannosyl-oligosaccharide alpha-D-mannohydrolase activity|alpha-1,6-mannosidase activity|1,6-alpha-mannosidase activity Catalysis of the hydrolysis of the alpha-(1->6) bonds of alpha-D-mannose residues in mannosyl-oligosaccharide. GO:0003752 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003752 CHEBI:29699 tunicamycin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_29699 CHEBI:15045 riboflavin cyclic 4',5'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15045 CHEBI:30684 alpha-D-glucosyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30684 GO:0052762 gellan lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052762 MetaCyc:RXN-12269|EC:4.2.2.25 Catalysis of the reaction: gellan = n beta-D-4-deoxy-delta4,5-GlcAp-(1->4)-beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-beta-D-Glcp. This reaction is the eliminative cleavage of beta-D-glucopyranosyl-(1->4)-beta-D-glucopyranosyluronate bonds of gellan backbone, releasing tetrasaccharides containing a 4-deoxy-4,5-unsaturated D-glucopyranosyluronic acid at the non-reducing end; in the product, the abbreviations are D-glucose (Glc), D-glucuronic acid (GlcA), and L-rhamnose (Rha). GO:0003759 obsolete glycoprotein-specific chaperone activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003759 glycoprotein-specific chaperone activity OBSOLETE. Assists in the correct, non-covalent assembly of glycoproteins in vivo, but is not a component of the assembled structures when performing its normal biological function. Utilizes a lectin site as a means to associate with the unfolded glycoproteins. CHEBI:39015 apolipoprotein biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39015 GO:0052761 exo-1,4-beta-D-glucosaminidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052761 KEGG_REACTION:R08715|MetaCyc:3.2.1.165-RXN|EC:3.2.1.165 chitosan exo-1,4-beta-D-glucosaminidase activity|exochitosanase activity|chitosan glucosaminohydrolase activity|exo-beta-D-glucosaminidase activity Catalysis of the reaction: [beta-(1->4)-D-glucosamine]n-[N-acetyl-D-glucosamine]m = D-glucosamine + [beta-(1->4)-D-glucosamine](n-1)-[N-acetyl-D-glucosamine]m. This reaction is the hydrolysis of chitosan or chitosan oligosaccharides to remove a D-glucosamine residue from the non-reducing termini; chitosan is a linear polysaccharide composed of randomly distributed beta-(1->4)-linked D-glucosamine and N-acetyl-D-glucosamine units. CHEBI:15040 retinyl palmitate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15040 GO:0003758 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003758 GO:0052760 coenzyme F420-dependent 2,4-dinitrophenol reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052760 EC:1.3.99.-|UM-BBD_reactionID:r1071 coenzyme F420-dependent 2,4-dinitrophenol hydride transferase activity|DNP reductase activity Catalysis of the reaction: 2,4-dinitrophenol + H- = 2,4-dinitrophenol hydride Meisenheimer complex. Coenzyme F420 supplies the hydride (H-) in the reaction. GO:0052777 diacetylchitobiose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052777 diacetylchitobiose catabolism The chemical reactions and pathways resulting in the breakdown of diacetylchitobiose into simpler products. GO:0003766 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003766 GO:0052776 diacetylchitobiose catabolic process to glucosamine and acetate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052776 The pathway resulting in the breakdown of diacetylchitobiose into simpler products, including glucosamine and glucosamine. The catabolism proceeds by the deacetylation of diacetylchitobiose, producing acetate and GlcN-GlcNAc; the latter is cleaved to produce glucosamine (GlcN) and N-acetylglucosamine (GlcNAc). The N-acetylglucosamine (GlcNAc) is then deacetylated to produce glucosamine (GlcN) and acetate. GO:0003765 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003765 GO:0003768 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003768 GO:0052775 endo-1,3-alpha-L-rhamnosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052775 endo-(1,3)-alpha-L-rhamnosidase activity|endorhamnosidase activity|endo-(1->3)-alpha-L-rhamnosidase activity Catalysis of the reaction: R1-L-rhamnose-(1->3)-alpha-L-rhamnose-R2 + H2O = R1-L-rhamnose + L-rhamnose-R2. This reaction is the hydrolysis of an alpha-(1->3) linkage between two rhamnose residues in a polysaccharide chain. GO:0003767 obsolete co-chaperone activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003767 co-chaperone activity OBSOLETE. Co-chaperones are proteins that bind to chaperones and this complex then folds misfolded proteins. Co-chaperones by themselves do not possess chaperone activity. GO:0052774 glucosyl-N-acetylglucosamine glucosaminidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052774 Catalysis of the reaction: glucosyl-N-acetylglucosamine + H2O = glucosamine + N-acetylglucosamine. GO:0003762 obsolete histone-specific chaperone activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003762 nucleosome assembly chaperone|histone-specific chaperone activity OBSOLETE. Assists in chromatin assembly by chaperoning histones on to replicating DNA, but is not a component of the assembled nucleosome when performing its normal biological function. CHEBI:64074 (S)-NADHX(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64074 GO:0003761 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003761 GO:0003764 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003764 GO:0052779 amino disaccharide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052779 The chemical reactions and pathways involving any amino disaccharide, a disaccharide having one or more substituted or unsubstituted amino groups in place of hydroxy groups at unspecified positions. CHEBI:88021 archaeal dolichyl N-acetyl-alpha-D-glucosaminyl phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88021 GO:0052778 diacetylchitobiose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052778 diacetylchitobiose metabolism The chemical reactions and pathways involving diacetylchitobiose, the N,N'-diacetylated derivative of chitobiose. GO:0003763 obsolete chaperonin ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003763 chaperonin ATPase activity|chaperonin OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP involved in maintaining an unfolded polypeptide structure before folding or to entry into mitochondria and chloroplasts. CHEBI:64077 (R)-NADPHX(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64077 CHEBI:64076 (S)-NADPHX(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64076 GO:0003760 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003760 CHEBI:64075 (R)-NADHX(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64075 CHEBI:88026 archaeal dolichyl 3-O-(2,3-diacetamido-2,3-dideoxy- beta-D-glucuronsyl)-N-acetyl- alpha-D-glucosaminyl phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88026 CHEBI:40009 D-cycloserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_40009 CHEBI:30697 beta-D-glucosyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_30697 CHEBI:39022 inclusion compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39022 CHEBI:15036 retinoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15036 CHEBI:15035 retinal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_15035 GO:0052773 diacetylchitobiose deacetylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052773 MetaCyc:RXN-12543 N,N'-diacetylchitobiose deacetylase (nonreducing end) Catalysis of the reaction: N,N'-diacetylchitobiose (GlcNac2) + H2O = acetate + 2-acetamido-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-D-glucose (GlcN-GlcNAc). CHEBI:39027 very-low-density lipoprotein biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39027 GO:0003769 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003769 GO:0052772 brefeldin A esterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052772 brefeldin A hydrolase activity|BFA esterase activity Catalysis of the hydrolysis of brefeldin A to produce brefeldin A acid. Brefeldin A is also known as gamma,4-dihydroxy-2-(6-hydroxy-1-heptenyl)-4-cyclopentanecrotonic acid lambda-lactone. CHEBI:39026 low-density lipoprotein biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39026 GO:0052771 coenzyme F390-G hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052771 8-hydroxyguanylylated-coenzyme F420 hydrolase activity Catalysis of the reaction: coenzyme F390-G = GMP + coenzyme F420. CHEBI:39025 high-density lipoprotein biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39025 CHEBI:15031 dihydroriboflavins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_15031 GO:0052770 coenzyme F390-A hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052770 8-hydroxyadenylylated-coenzyme F420 hydrolase activity Catalysis of the reaction: coenzyme F390-A = AMP + coenzyme F420. CHEBI:39024 clathrate compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39024 GO:0052788 d-4,5 unsaturated beta-glucuronyl hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052788 unsaturated beta-glucuronyl hydrolase activity Catalysis of the hydrolysis of the glycosidic bond in an unsaturated saccharide between the unsaturated glucuronyl residue at the nonreducing terminus and the saccharide linked to the residue. GO:0003733 obsolete ribonucleoprotein biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003733 ribonucleoprotein OBSOLETE. (Was not defined before being made obsolete). GO:0052787 alpha-linked polysaccharide catabolism to maltopentaose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052787 alpha-amylase-mediated polysaccharide catabolism, producing maltopentaose|maltopentaose-forming alpha-amylase activity The breakdown of large alpha-linked polysaccharides by hydrolysis of (1->4)-alpha-D-glucosidic linkages to yield maltopentaose. GO:0003732 obsolete snRNA cap binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003732 snRNA cap binding OBSOLETE. Interacting selectively with the cap structure at the 5' end of a small nuclear RNA molecule. GO:0003735 structural constituent of ribosome biolink:MolecularActivity go-plus goslim_chembl|goslim_yeast|goslim_drosophila|goslim_metagenomics|goslim_generic http://purl.obolibrary.org/obo/GO_0003735 ribosomal protein|ribosomal RNA The action of a molecule that contributes to the structural integrity of the ribosome. GO:0052786 alpha-linked polysaccharide catabolism to maltotriose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052786 alpha-amylase-mediated polysaccharide catabolism, producing maltotriose|maltotriose-forming alpha-amylase activity The breakdown of large alpha-linked polysaccharides by hydrolysis of (1->4)-alpha-D-glucosidic linkages to yield maltotriose. GO:0052785 cellulose catabolism by endo-processive cellulases biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052785 endo-processive cellulase activity The breakdown into simpler components of cellulose. Catabolism is initiated by endohydrolytic attacks on the cellulose chain, and the resulting pieces are further degraded by cellulase enzymes to produce smaller and smaller fragments. GO:0003734 obsolete small nuclear ribonucleoprotein biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003734 small nuclear ribonucleoprotein|snRNP OBSOLETE. (Was not defined before being made obsolete). CHEBI:88052 prenyl phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88052 CHEBI:64085 (R)-NADPHX biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64085 CHEBI:29678 sodium arsenite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29678 CHEBI:64084 (S)-NADPHX biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64084 GO:0003731 obsolete mRNA cap binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003731 mRNA cap binding OBSOLETE. Interacting selectively with the 7-methylguanosine cap at the 5' end of a nascent messenger RNA transcript. CHEBI:88054 [5-(ammoniomethyl)-3-furyl]methyl diphosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88054 GO:0052789 mannan 1,3-beta-mannosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052789 exo-1,3-mannanase activity|beta-1,3-mannan 3-mannanohydrolase activity|1,3-beta-D-mannan mannanohydrolase activity|exo-1,3-beta-mannanase activity|exo-beta-1,3-mannase activity Catalysis of the hydrolysis of (1->3)-beta-D-mannosidic linkages in mannans, releasing mannose. CHEBI:88053 phosphatidyl-myo-inositol 6-acylmannoside(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88053 GO:0003730 mRNA 3'-UTR binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003730 mRNA 3' UTR binding Interacting selectively and non-covalently with the 3' untranslated region of an mRNA molecule. CHEBI:88056 ganglioside GM1/1b(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88056 CHEBI:88055 (4-{4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88055 CHEBI:88058 ganglioside GT1(3-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88058 CHEBI:88057 ganglioside GD1(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88057 GO:0062110 negative regulation of DNA recombinase disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062110 Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombinase complex disassembly, the disaggregation of a DNA recombinase complex into its constituent components. CHEBI:88059 ganglioside GQ1(4-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88059 GO:0062112 fatty acid primary amide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062112 fatty acid amide biosynthesis|FAPA biosynthesis|FAPA biosynthetic process The chemical reactions and pathways resulting in the formation of a fatty acid primary amide. CHEBI:29673 rifamycin SV biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_29673 GO:0062111 zinc ion import into organelle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062111 The directed import of zinc(2+) from the cytosol, across an organelle membrane, into the organelle. GO:0062113 early phagosome lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062113 early phagocytic vesicle lumen The volume enclosed by the membrane of an eary phagosome. GO:0062116 phenyloplast biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062116 A chloroplast-derived plastid in which the solid form of phenol is stored. GO:0062119 LinE complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0062119 A protein complex that associates with chromatin to form linear elements in fission yeast. In S. pombe, the LinE complex contains four main structural components (Rec10, Rec25, Rec27, and Mug20) and other associated proteins. GO:0052780 chitobiose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052780 The chemical reactions and pathways involving chitobioses, a family of compounds derived from chitin and based on the structure of D-glucosaminyl-(1->4)-D-glucosamine. CHEBI:30661 thyronine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30661 GO:0052784 reuteran biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052784 reuteransucrase-mediated reuteran biosynthesis The chemical reactions and pathways resulting in the formation of reuteran, a soluble glucan polymer with mainly alpha-(1->4) glycosidic linkages and significant amounts of alpha-(1->6) and alpha-(1->4,6) glucosidic linkages. CHEBI:30660 thyroxine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_30660 GO:0003737 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003737 GO:0052783 reuteran metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052783 The chemical reactions and pathways involving reuteran, a soluble glucan polymer with mainly alpha-(1->4) glycosidic linkages and significant amounts of alpha-(1->6) and alpha-(1->4,6) glucosidic linkages. GO:0003736 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003736 GO:0052782 amino disaccharide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052782 The chemical reactions and pathways resulting in the breakdown of any amino disaccharide, a disaccharide having one or more substituted or unsubstituted amino groups in place of hydroxy groups at unspecified positions. GO:0003739 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003739 GO:0052781 chitobiose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052781 The chemical reactions and pathways resulting in the breakdown of any chitobiose, a family of compounds derived from chitin and based on the structure of D-glucosaminyl-(1->4)-D-glucosamine. GO:0003738 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003738 GO:0003744 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003744 GO:0052799 coenzyme F420-dependent bicyclic nitroimidazole catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052799 coenzyme F420-dependent nitroimidazole breakdown|coenzyme F420-dependent nitroimidazole catabolism|coenzyme F420-dependent nitroimidazole reduction|coenzyme F420-dependent nitroreductase activity The breakdown of a bicyclic nitroimidazole into simpler components in a process that requires coenzyme F420 and produces reactive nitrogen species. Hydride, from reduced coenzyme F420, is added to the bicyclic nitroimidazole, resulting in unstable substances that break down to form three stable products. The elimination of nitrous acid produces the corresponding des-nitroimidazole; hydrolysis produces a related compound; and further reduction creates an aromatic hydroxylamine metabolite that degrades further. These reactions release hyponitrous acid and nitrous acid, which is unstable and disproportionates into nitric oxide (NO) and other reactive nitrogen intermediates. GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052798 trans-sialidase activity Catalysis of the transfer of sialyl residues alpha-2,3-linked to a beta galactosyl residue on the donor to form an alpha-2,3 linkage to a terminal beta galactosyl residue on the acceptor. GO:0003743 translation initiation factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003743 Reactome:R-HSA-72722|Reactome:R-HSA-72697|Reactome:R-HSA-72621 Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide. GO:0003746 translation elongation factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003746 Reactome:R-HSA-192841|Reactome:R-HSA-192704 Functions in chain elongation during polypeptide synthesis at the ribosome. GO:0052797 4-O-methyl-glucuronoyl methylesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052797 glucuronoyl esterase activity Catalysis of the reaction: [X]-4-O-methyl-D-glucuronic acid + H2O = [X]-OH + methyl-D-glucuronic acid. This reaction is the hydrolysis of the ester linkage between 4-O-methyl-D-glucuronic acid (MeGlcA) and an alcohol (-OH) group attached to a molecule, denoted here as [X]. CHEBI:64090 tert-butyl hydroperoxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64090 GO:0003745 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003745 GO:0052796 exo-alpha-(2->8)-sialidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052796 EC:3.2.1.18 exo-alpha-2,8-sialidase activity|exo-alpha-(2,8)-sialidase activity Catalysis of the hydrolysis of alpha-(2->8)-glycosidic linkages of terminal sialic residues in substrates. GO:0003740 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003740 CHEBI:88041 CDP-3,6-dideoxy-alpha-D-mannose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88041 GO:1904309 response to cordycepin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904309 response to 3'-deoxyadenosine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cordycepin stimulus. GO:0003742 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003742 GO:1904308 cellular response to desipramine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904308 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desipramine stimulus. GO:0003741 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003741 CHEBI:88042 UDP-beta-L-iduronate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_88042 GO:1904307 response to desipramine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904307 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desipramine stimulus. GO:1904306 positive regulation of gastro-intestinal system smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904306 upregulation of gastro-intestinal system smooth muscle contraction|up-regulation of gastro-intestinal system smooth muscle contraction|activation of gastro-intestinal system smooth muscle contraction|up regulation of gastro-intestinal system smooth muscle contraction Any process that activates or increases the frequency, rate or extent of gastro-intestinal system smooth muscle contraction. GO:1904305 negative regulation of gastro-intestinal system smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904305 down regulation of gastro-intestinal system smooth muscle contraction|inhibition of gastro-intestinal system smooth muscle contraction|down-regulation of gastro-intestinal system smooth muscle contraction|downregulation of gastro-intestinal system smooth muscle contraction Any process that stops, prevents or reduces the frequency, rate or extent of gastro-intestinal system smooth muscle contraction. GO:1904304 regulation of gastro-intestinal system smooth muscle contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904304 Any process that modulates the frequency, rate or extent of gastro-intestinal system smooth muscle contraction. GO:1904303 positive regulation of maternal process involved in parturition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904303 up regulation of maternal process involved in parturition|upregulation of maternal process involved in parturition|up-regulation of maternal process involved in parturition|activation of maternal process involved in parturition Any process that activates or increases the frequency, rate or extent of maternal process involved in parturition. UBERON:2005227 protoneuromast biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_2005227 immature neuromast|proto neuromast|proto-neuromast GO:1904302 negative regulation of maternal process involved in parturition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904302 downregulation of maternal process involved in parturition|down regulation of maternal process involved in parturition|inhibition of maternal process involved in parturition|down-regulation of maternal process involved in parturition Any process that stops, prevents or reduces the frequency, rate or extent of maternal process involved in parturition. CHEBI:88048 cyanotoxin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_88048 GO:0062101 peptidyl-aspartic acid 3-dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062101 EC:1.14.11.16|MetaCyc:PEPTIDE-ASPARTATE-BETA-DIOXYGENASE-RXN|RHEA:11508 Catalysis of the reaction: protein L-aspartate + 2-oxoglutarate + O2 = protein 3-hydroxy-L-aspartate + succinate + CO2. GO:1904301 regulation of maternal process involved in parturition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904301 Any process that modulates the frequency, rate or extent of maternal process involved in parturition. GO:0062100 positive regulation of programmed necrotic cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062100 Any process that increases the frequency, rate or extent of programmed necrotic cell death. GO:1904300 positive regulation of transcytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904300 up regulation of transcytosis|upregulation of transcytosis|up-regulation of transcytosis|activation of transcytosis Any process that activates or increases the frequency, rate or extent of transcytosis. GO:0062103 double-stranded RNA biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062103 double-stranded RNA biosynthesis|dsRNA biosynthetic process|dsRNA biosynthesis The chemical reactions and pathways resulting in the formation of double-stranded RNA. GO:1904310 cellular response to cordycepin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1904310 cellular response to 3'-deoxyadenosine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cordycepin stimulus. GO:0062102 female germline stem cell symmetric division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062102 Division of a female germline stem cell to produce two germline stem cells of the same type as the parent. GO:0062105 RNA 2'-O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062105 RHEA:58956 Catalysis of the reaction: S-adenosyl-L-methionine + RNA = S-adenosyl-L-homocysteine + RNA containing 2'-O-methylribonucleotide. GO:0062104 pumilio-response element binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0062104 PRE binding Interacting selectively and non-covalently with a region of RNA containing a Pumilio-response element element. The consensus sequence for the element is UGUAAAUA. GO:0062107 regulation of protein localization to non-growing cell tip biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062107 Any process that modulates the frequency, rate or extent of protein localization to a non-growing cell tip. GO:0062109 regulation of DNA recombinase disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062109 Any process that modulates the rate, frequency or extent of DNA recombinase disassembly, the disaggregation of a DNA recombinase complex into its constituent components. GO:0062108 negative regulation of protein localization to non-growing cell tip biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0062108 Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to a non-growing cell tip. GO:0052791 3-deoxy-D-glycero-D-galacto-2-nonulosonic acid hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052791 2-keto-3-deoxynononic acid sialidase activity Catalysis of the reaction: (2-keto-3-deoxynononic acid)n + H2O = (2-keto-3-deoxynononic acid)n-1 + 2-keto-3-deoxynononic acid. This reaction is the hydrolysis of a 2-keto-3-deoxynononic acid residue from a poly-2-keto-3-deoxynononic acid chain. GO:0052790 chitooligosaccharide deacetylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052790 EC:3.5.1.- Catalysis of the reaction: chitooligosaccharide with N-acetylglucosamine at nonreducing terminal + H2O = chitooligosaccharide with glucosamine at nonreducing terminal + acetate. This reaction is the deacetylation of a chitooligosaccharide at the nonreducing N-acetylglucosamine residue; chitooligosaccharide are composed of (1->4)-linked D-glucosamine (GlcN) and N-acetyl-D-glucosamine (GlcNAc) in varying proportions. CHEBI:39000 sodium channel modulator biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39000 GO:0003748 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003748 GO:0052795 exo-alpha-(2->6)-sialidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052795 EC:3.2.1.18 exo-alpha-2,6-sialidase activity|exo-alpha-(2,6)-sialidase activity Catalysis of the hydrolysis of alpha-(2->6)-glycosidic linkages of terminal sialic residues in substrates. GO:0003747 translation release factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0003747 Involved in catalyzing the release of a nascent polypeptide chain from a ribosome. GO:0052794 exo-alpha-(2->3)-sialidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052794 EC:3.2.1.18 exo-alpha-(2,3)-sialidase activity|exo-alpha-2,3-sialidase activity Catalysis of the hydrolysis of alpha-(2->3)-glycosidic linkages of terminal sialic residues in substrates. GO:0052793 pectin acetylesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052793 Catalysis of the reaction: pectin + H2O = pectate + acetate. This reaction is the hydrolysis of acetyl esters of pectin, producing pectate, partially esterified pectin. GO:0003749 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0003749 GO:0052792 endo-xylogalacturonan hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052792 endo-galacturonase activity Catalysis of the endohydrolysis of xylogalacturonate by cleavage of the alpha-(1,4)-linkage. Xylogalacturonate (XGA) is composed of a chain of alpha-(1,4)-linked D-galacturonic acid residues with beta-D-xylose substituted at the O3 position. CHEBI:78605 7-oxolithocholate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78605 CHEBI:78604 ursodeoxycholate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78604 CHEBI:78603 3beta-hydroxy-7-oxo-5beta-cholan-24-oate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78603 CHEBI:78608 alpha-amino acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78608 CHEBI:78607 alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78607 CHEBI:78602 isoursodeoxycholate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78602 CHEBI:78601 11,21-dioxoprogesterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78601 CHEBI:78600 11-dehydrocorticosterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78600 CHEBI:78616 carbohydrates and carbohydrate derivatives biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78616 CHEBI:78619 iron(III) oxide-hydroxide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78619 CHEBI:78613 C-terminal L-Ala-L-Leu-L-valinamide-N-CH=CH-S residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78613 CHEBI:78612 C-terminal L-Cys-L-Leu-L-Val-L-Cys(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78612 CHEBI:78611 3-hydroxybutanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78611 CHEBI:78628 2-hydroxyglutaryl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78628 CHEBI:78625 clavaldehyde(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78625 CHEBI:78629 N-(6-aminohexanoyl)-6-aminohexanoic acid zwitterion monomer biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78629 CHEBI:40096 adenosine 5'-(hexahydrogen pentaphosphate) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_40096 CHEBI:78620 3-methoxy-5-methyl-1-naphthoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78620 CHEBI:78624 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_78624 CHEBI:78636 vitexin 2''-O-beta-L-rhamnoside(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78636 CHEBI:146448 beta-D-Xylp-(1->6)-D-Glcp biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_146448 CHEBI:78631 chroman-6-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78631 CHEBI:78630 9-cis-retinoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78630 GO:0052700 ergothioneine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052700 ergothioneine degradation|2-mercaptoergothioneine trimethylbetaine degradation|2-mercaptoergothioneine trimethylbetaine breakdown|ergothioneine breakdown|ergothioneine catabolism|2-mercaptoergothioneine trimethylbetaine catabolism|2-mercaptoergothioneine trimethylbetaine catabolic process|(2S)-3-(2-mercapto-1H-imidazol-5-yl)-2-(trimethylazaniumyl)propanoate catabolic process The chemical reactions and pathways resulting in the breakdown of ergothioneine, a naturally occurring metabolite of histidine with antioxidant properties. CHEBI:40070 4-hydroxycoumarin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_40070 CHEBI:78647 N-hexadecanoylsphinganine-1-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78647 GO:0052704 ergothioneine biosynthesis from histidine via gamma-glutamyl-hercynylcysteine sulfoxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052704 Wikipedia:Ergothioneine ergothioneine biosynthesis from histidine via N-alpha,N-alpha,N-alpha-trimethyl-L-histidine The pathway resulting in the formation of ergothioneine from histidine via a set of steps in which gamma-glutamyl-hercynylcysteine sulfoxide is formed as an intermediate. GO:0052703 cellular modified histidine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052703 cellular histidine derivative formation|cellular modified histidine biosynthesis|histidine derivative biosynthetic process|cellular modified histidine anabolism|cellular modified histidine synthesis|cellular modified histidine formation|cellular histidine derivative biosynthetic process|cellular histidine derivative biosynthesis|cellular histidine derivative anabolism|cellular histidine derivative synthesis The chemical reactions and pathways resulting in the formation of compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid. GO:0052702 cellular modified histidine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052702 modified histidine catabolic process|cellular modified histidine degradation|modified histidine catabolism|cellular modified histidine breakdown|histidine derivative catabolic process|cellular histidine derivative degradation|cellular histidine derivative breakdown|cellular histidine derivative catabolic process|cellular histidine derivative catabolism|cellular modified histidine catabolism The chemical reactions and pathways resulting in the breakdown of compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid. GO:0052701 cellular modified histidine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052701 cellular modified histidine metabolism|histidine derivative metabolic process|modified histidine metabolism|cellular histidine derivative metabolic process|modified histidine metabolic process|cellular histidine derivative metabolism The chemical reactions and pathways involving compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid. GO:0052708 N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052708 hercynine metabolism|hercynine metabolic process|N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolism|histidine betaine metabolism|histidine betaine metabolic process The chemical reactions and pathways involving N-alpha,N-alpha,N-alpha-trimethyl-L-histidine, also known as histidine betaine or hercynine, a trimethylated derivative of histidine. GO:0052707 N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthesis from histidine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052707 KEGG_REACTION:R01169 histidine catabolism to hercynine|histidine catabolism to N-alpha,N-alpha,N-alpha-trimethyl-L-histidine|hercynine biosynthesis from histidine|histidine catabolic process to hercynine|histidine betaine biosynthesis from histidine The pathway resulting in the formation of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine from histidine. Histidine undergoes three methylations by a histidine-alpha-N-methyltransferase (EC:2.1.1.44) to form N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (also known as hercynine or histidine betaine). GO:0052706 histidine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052706 histidine methyltransferase activity|S-adenosyl-L-methionine:L-histidine Nalpha-methyltransferase activity|histidine-alpha-N-methyltransferase activity|S-adenosyl-L-methionine:L-histidine alpha-N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + L-histidine = S-adenosyl-L-homocysteine + N-alpha,N-alpha,N-alpha-trimethyl-L-histidine. GO:0052705 methylhistidine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052705 S-adenosyl-L-methionine:alpha-N-dimethyl-L-histidine alpha-N-methyltransferase activity|S-adenosyl-L-methionine:N-alpha-dimethyl-L-histidine N-alpha-methyltransferase activity|methylhistidine methyltransferase activity|histidine-alpha-N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + N-alpha-methyl-L-histidine = S-adenosyl-L-homocysteine + N-alpha,N-alpha-dimethyl-L-histidine. CHEBI:64005 DHET biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64005 GO:0052709 N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052709 hercynine formation|N-alpha,N-alpha,N-alpha-trimethyl-L-histidine synthesis|histidine betaine anabolism|N-alpha,N-alpha,N-alpha-trimethyl-L-histidine formation|histidine betaine synthesis|histidine betaine formation|histidine betaine biosynthetic process|histidine betaine biosynthesis|N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthesis|hercynine anabolism|hercynine synthesis|hercynine biosynthesis|hercynine biosynthetic process|N-alpha,N-alpha,N-alpha-trimethyl-L-histidine anabolism The chemical reactions and pathways resulting in the formation of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine, also known as histidine betaine or hercynine, a trimethylated derivative of histidine. CHEBI:64009 hydroperoxy fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64009 CHEBI:64008 (8E,12Z)-10-hydroperoxy-8,12-octadecadienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64008 CHEBI:64007 EET biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64007 CHEBI:64006 (8E,10R,12Z)-10-hydroperoxy-8,12-octadecadienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64006 CHEBI:78640 7-O-methylvitexin 2''-O-beta-L-rhamnoside(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78640 CHEBI:78646 N-hexadecanoylsphingosine-1-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78646 GO:0052711 obsolete ergothioneine biosynthesis from N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052711 KEGG_REACTION:R04878 histidine betaine catabolism to ergothioneine|ergothioneine biosynthesis from hercynine|ergothioneine biosynthesis from histidine betaine|hercynine catabolism to ergothioneine|N-alpha,N-alpha,N-alpha-trimethyl-L-histidine catabolism to ergothioneine OBSOLETE. The pathway resulting in the formation of ergothioneine from N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (also known as hercynine or histidine betaine). GO:0052710 N-alpha,N-alpha,N-alpha-trimethyl-L-histidine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0052710 N-alpha,N-alpha,N-alpha-trimethyl-L-histidine catabolism|N-alpha,N-alpha,N-alpha-trimethyl-L-histidine breakdown|histidine betaine breakdown|hercynine catabolism|histidine betaine catabolic process|hercynine degradation|hercynine breakdown|N-alpha,N-alpha,N-alpha-trimethyl-L-histidine degradation|histidine betaine catabolism|hercynine catabolic process|histidine betaine degradation The chemical reactions and pathways resulting in the breakdown of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine, also known as histidine betaine or hercynine, a trimethylated derivative of histidine. GO:0052715 mannosyl-diinositol phosphorylceramide phospholipase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052715 Catalysis of the reaction: mannosyl-diinositol phosphorylceramide + H2O = C26-phytoceramide + mannosyldiphosphorylinositol. GO:0052714 mannosyl-inositol phosphorylceramide phospholipase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052714 Catalysis of the reaction: mannosyl-inositol phosphorylceramide + H2O = C26-phytoceramide + mannosylphosphorylinositol. GO:0052713 inositol phosphorylceramide phospholipase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052713 Catalysis of the reaction: inositol phosphorylceramide + H2O = C26-phytoceramide + phosphorylinositol. GO:0052712 inositol phosphosphingolipid phospholipase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052712 Catalysis of the reaction: inositol phosphosphingolipid + H2O = sphingolipid + phosphorylinositol. CHEBI:39093 organophosphorus pesticide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_39093 GO:0052719 apurinic/apyrimidinic endoribonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052719 apurinic endoribonuclease activity|AP endoribonuclease activity|abasic endoribonuclease activity|apyrimidinic endoribonuclease activity Catalysis of the hydrolysis of ester linkages immediately 5' to an apurinic/apyrimidinic (AP; also called abasic) site within a ribonucleic acid molecule by creating internal breaks, generating a single-strand break with 5'-ribose phosphate and 3'-hydroxyl ends. CHEBI:64012 hydroperoxy fatty acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64012 GO:0052718 tRNA-specific adenosine-34 deaminase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0052718 tRNA-A34 deaminase complex A protein complex that possesses tRNA-specific adenosine-34 deaminase activity. In eukaryotes the complex is a heterodimer; the subunits are known as Tad2p and Tad3p in yeasts and Adat2 and Adat3 in human. CHEBI:64011 (3Z)-2-oxohex-3-enedioate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64011 GO:0052717 tRNA-specific adenosine-34 deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052717 tRNA(Ala)-A34 deaminase activity Catalysis of the reaction: adenosine-34 + H2O = inosine-34 + NH3, in a tRNA-Ala molecule. GO:0052716 hydroquinone:oxygen oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0052716 RHEA:11276|MetaCyc:LACCASE-RXN|KEGG_REACTION:R00083|EC:1.10.3.2 p-diphenol:oxygen oxidoreductase activity|laccase reaction|benzenediol:oxygen oxidoreductase activity Catalysis of the reaction: 4 hydroquinone + O2 = 4 benzosemiquinone + 4 H2O. CHEBI:64016 (2E,4Z)-2-hydroxymuconate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_64016 CHEBI:64014 (5Z,8Z,10E,12E)-icosatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64014 CHEBI:64018 protein kinase C agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64018 CHEBI:64017 (5Z,8Z,11Z,13E)-15-HETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_64017 CHEBI:78651 N-acylphytosphingosine-1-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78651 CHEBI:78650 N-hexadecanoylphytosphingosine-1-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78650 CHEBI:78657 N-acylphytosphingosine-1-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78657 CHEBI:78656 N-hexadecanoylphytosphingosine-1-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78656 CHEBI:78655 N-acylsphinganine-1-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78655 CHEBI:78654 N-hexadecanoylsphinganine-1-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_78654 GO:0032439 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032439 GO:0032438 melanosome organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032438 melanosome organisation|melanosome organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a melanosome. A melanosome is a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. GO:0032437 cuticular plate biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032437 A dense network of actin filaments found beneath the apical cell surface of hair cells, and into which stereocilia are inserted. GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032436 up-regulation of proteasomal ubiquitin-dependent protein catabolic process|upregulation of proteasomal ubiquitin-dependent protein catabolic process|up regulation of proteasomal ubiquitin-dependent protein catabolic process|activation of proteasomal ubiquitin-dependent protein catabolic process|stimulation of proteasomal ubiquitin-dependent protein catabolic process Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome. GO:0007479 leg disc proximal/distal pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007479 The establishment, maintenance and elaboration of the proximal/distal axis of the leg imaginal disc, a precursor to the adult leg. GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032435 down regulation of proteasomal ubiquitin-dependent protein catabolic process|downregulation of proteasomal ubiquitin-dependent protein catabolic process|down-regulation of proteasomal ubiquitin-dependent protein catabolic process|inhibition of proteasomal ubiquitin-dependent protein catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome. GO:0007478 leg disc morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007478 leg disc metamorphosis The process in which the anatomical structures derived from the leg disc are generated and organized. This includes the transformation of a leg imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the leg, coxa and ventral thoracic pleura. GO:0007477 notum development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007477 The process whose specific outcome is the progression of the dorsal part of the body over time, from its formation to the mature structure. GO:0007476 imaginal disc-derived wing morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007476 wing morphogenesis The process in which the anatomical structures of the imaginal disc-derived wing are generated and organized. The wing is an appendage modified for flying. GO:0007475 apposition of dorsal and ventral imaginal disc-derived wing surfaces biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007475 apposition of dorsal and ventral wing surfaces The coming together of the dorsal and ventral surfaces of the imaginal disc-derived wing during the conversion of a folded single layered wing disc to a flat bilayered wing. CHEBI:79081 cyclic 2,3-bisphospho-D-glycerate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79081 GO:0007474 imaginal disc-derived wing vein specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007474 wing vein specification The regionalization process in which the area of a imaginal disc-derived wing that will form a wing vein is specified. CHEBI:79080 lactose 6-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79080 GO:0007473 wing disc proximal/distal pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007473 The establishment, maintenance and elaboration of the proximal/distal axis of the wing disc, a precursor to the adult wing. GO:0007472 wing disc morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007472 wing disc metamorphosis The process in which the anatomical structures derived from the wing disc are generated and organized. This includes the transformation of a wing imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the wing hinge, wing blade and pleura. PR:000006165 C-C motif chemokine 12 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000006165 Mcp5|Scya12|MCP-1-related chemokine|small-inducible cytokine A12|Ccl12|monocyte chemoattractant protein 5|MCP-5|monocyte chemotactic protein 5 An eotaxin-like cytokine that is a translation product of the mouse Ccl12 gene or a 1:1 ortholog thereof. GO:0007471 obsolete prothoracic morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007471 prothoracic morphogenesis OBSOLETE. The process by which the anatomical structures of the first or anterior segment of the insect thorax are generated and organized. GO:0007481 haltere disc morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007481 haltere disc metamorphosis The process in which the anatomical structures derived from the haltere disc are generated and organized. This includes the transformation of a haltere imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult capitellum, pedicel, haltere sclerite, metathoracic spiracle and metanotum. CHEBI:79074 1,2-dicapryl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79074 GO:0007480 imaginal disc-derived leg morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007480 The process in which the anatomical structures of a leg derived from an imaginal disc are generated and organized. A leg is a limb on which an animal walks and stands. An example of this is found in Drosophila melanogaster. CHEBI:79072 15-ketoprostaglandin F1alpha(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79072 CHEBI:79071 selenoneine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79071 CHEBI:79077 5-hydroxy-3-methyl-L-tyrosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79077 CHEBI:79076 3-methyl-L-tyrosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79076 CHEBI:79075 1,2-dioctanoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79075 GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032434 Any process that modulates the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome. GO:0032433 filopodium tip biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032433 The end of a filopodium distal to the body of the cell. GO:0032432 actin filament bundle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032432 actin cable An assembly of actin filaments that are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness. GO:0032431 activation of phospholipase A2 activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032431 phospholipase A2 activation Any process that initiates the activity of the inactive enzyme phospholipase A2. CHEBI:79079 (4S)-4-hydroxy-L-isoleucine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79079 GO:0032430 positive regulation of phospholipase A2 activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032430 upregulation of phospholipase A2 activity|up regulation of phospholipase A2 activity|activation of phospholipase A2 activity|stimulation of phospholipase A2 activity|up-regulation of phospholipase A2 activity Any process that activates or increases the activity of the enzyme phospholipase A2. GO:0032429 regulation of phospholipase A2 activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032429 Any process that modulates the activity of the enzyme phospholipase A2. GO:0032428 beta-N-acetylgalactosaminidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032428 MetaCyc:3.2.1.53-RXN|EC:3.2.1.53 Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in N-acetyl-beta-D-galactosaminides. GO:0032427 GBD domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032427 PMD binding|Cdc42/Rac interactive binding motif binding|CRIB motif binding|P21-Rho-binding domain binding Interacting selectively and non-covalently with the GTPase protein binding domain (GDB) domain of a protein. The GBD is a short motif, including a minimum region of 16 amino acids, identified in proteins that bind to small GTPases such as Cdc42 and Rac. CHEBI:137150 (R)-5-[2-(methylthio)ethyl]hydantoin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137150 GO:0032426 stereocilium tip biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032426 A distinct compartment at the tip of a stereocilium, distal to the site of attachment to the apical cell surface. It consists of a dense matrix bridging the barbed ends of the stereocilium actin filaments with the overlying plasma membrane, is dynamic compared to the shaft, and is required for stereocilium elongation. GO:0032425 positive regulation of mismatch repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032425 up regulation of mismatch repair|activation of mismatch repair|stimulation of mismatch repair|up-regulation of mismatch repair|upregulation of mismatch repair Any process that activates or increases the frequency, rate or extent of mismatch repair. GO:0032424 negative regulation of mismatch repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032424 down-regulation of mismatch repair|inhibition of mismatch repair|down regulation of mismatch repair|downregulation of mismatch repair Any process that stops, prevents, or reduces the frequency, rate or extent of mismatch repair. GO:0007489 maintenance of imaginal histoblast diploidy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007489 The negative regulation of the differentiation of polytenized larval hypodermal cells from abdominal histoblasts. The abdominal histoblasts remain a small cluster of diploid cells among the polytenized larval hypodermal cells. GO:0007488 histoblast morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007488 histoblast metamorphosis The process in which the anatomical structures derived from the histoblast disc are generated and organized. This includes the transformation of histoblast cells into adult structures during pupal metamorphosis. Histoblast cells are cells founded in the embryo that are the progenitors to the adult abdomen. GO:0007487 analia development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007487 The process whose specific outcome is the progression of the analia over time, from its formation to the mature structure. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is analia development in Drosophila melanogaster. GO:0007486 imaginal disc-derived female genitalia development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007486 female genital development The process whose specific outcome is the progression of the female genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster. GO:0007485 imaginal disc-derived male genitalia development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007485 male genital development The process whose specific outcome is the progression of the male genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster. GO:0007484 imaginal disc-derived genitalia development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007484 genital development The process whose specific outcome is the progression of the genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster. CHEBI:79091 EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79091 GO:0007483 genital disc morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007483 genital disc metamorphosis The process in which the anatomical structures derived from the genital disc are generated and organized. This includes the transformation of a genital imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult genital structures, the anal plates and the hind gut. GO:0007482 haltere development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007482 The process whose specific outcome is the progression of the haltere over time, from its formation to the mature structure. The haltere is the club-shaped 'balancers' found on each side of the metathorax among the true flies (Diptera). They are the much-modified hind wings. GO:0007492 endoderm development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007492 The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues. GO:0007491 sternite morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007491 The process in which the anatomical structures of the sternite are generated and organized. The sternite is the plate or sclerite on the underside of a body segment. CHEBI:79084 tricyclic diterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79084 GO:0007490 tergite morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007490 The process in which the anatomical structures of the tergite are generated and organized. The tergite is the primary plate or sclerite forming the dorsal surface of any insect body segment. CHEBI:79083 3-hydroxy-5-methyl-1-naphthoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79083 CHEBI:79082 5-methyl-1-naphthoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79082 GO:0032423 regulation of mismatch repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032423 Any process that modulates the frequency, rate or extent of mismatch repair. GO:0032422 purine-rich negative regulatory element binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032422 PNR element binding Interacting selectively and non-covalently with a 30-bp purine-rich negative regulatory element; the best characterized such element is found in the first intronic region of the rat cardiac alpha-myosin heavy chain gene, and contains two palindromic high-affinity Ets-binding sites (CTTCCCTGGAAG). The presence of this element restricts expression of the gene containing it to cardiac myocytes. GO:0032421 stereocilium bundle biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0032421 stereocilia bundle A bundle of cross-linked stereocilia, arranged around a kinocilium on the apical surface of a sensory hair cell (e.g. a neuromast, auditory or vestibular hair cell). Stereocilium bundles act as mechanosensory organelles by responding to fluid motion or fluid pressure changes. GO:0032420 stereocilium biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032420 An actin-based protrusion from the apical surface of auditory and vestibular hair cells and of neuromast cells. These protrusions are supported by a bundle of cross-linked actin filaments (an actin cable), oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex which bridges to the plasma. Bundles of stereocilia act as mechanosensory organelles. SO:0005836 regulatory_region biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0005836 http://en.wikipedia.org/wiki/Regulatory_region regulatory region|INSDC_qualifier:other|INSDC_feature:regulatory A region of sequence that is involved in the control of a biological process. CHEBI:137145 15-hydroxy-(5Z,8Z,11Z,13E)-icosatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137145 GO:0032419 extrinsic component of lysosome membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032419 extrinsic to lysosome membrane|extrinsic to lysosomal membrane The component of an lysosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:0032418 lysosome localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032418 lysosome localisation Any process in which a lysosome is transported to, and/or maintained in, a specific location. GO:0032417 positive regulation of sodium:proton antiporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032417 upregulation of sodium:hydrogen antiporter activity|up regulation of sodium:hydrogen antiporter activity|positive regulation of sodium:hydrogen antiporter activity|activation of sodium:hydrogen antiporter activity|stimulation of sodium:hydrogen antiporter activity|up-regulation of sodium:hydrogen antiporter activity Any process that activates or increases the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out). GO:0032416 negative regulation of sodium:proton antiporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032416 down regulation of sodium:hydrogen antiporter activity|downregulation of sodium:hydrogen antiporter activity|down-regulation of sodium:hydrogen antiporter activity|negative regulation of sodium:hydrogen antiporter activity|inhibition of sodium:hydrogen antiporter activity Any process that stops or reduces the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out). GO:0032415 regulation of sodium:proton antiporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032415 regulation of sodium:hydrogen antiporter activity Any process that modulates the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out). GO:0007459 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007459 GO:0032414 positive regulation of ion transmembrane transporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032414 stimulation of ion transporter activity|up-regulation of ion transporter activity|activation of ion transporter activity|positive regulation of ion transporter activity|up regulation of ion transporter activity|upregulation of ion transporter activity Any process that activates or increases the activity of an ion transporter. GO:0007458 progression of morphogenetic furrow involved in compound eye morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007458 progression of morphogenetic furrow during compound eye morphogenesis The morphogenetic furrow is a dorsoventral indentation which sweeps anteriorly across the eye disc. Ommatidia begin to form along the furrow, resulting in a graded series of ommatidial development across the anterior/posterior axis of the disc. GO:0032413 negative regulation of ion transmembrane transporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032413 negative regulation of ion transporter activity|down-regulation of ion transporter activity|downregulation of ion transporter activity|down regulation of ion transporter activity|inhibition of ion transporter activity Any process that stops or reduces the activity of an ion transporter. GO:0007457 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007457 GO:0007456 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007456 GO:0007455 eye-antennal disc morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007455 eye-antennal disc metamorphosis The process in which the anatomical structures derived from the eye-antennal disc are generated and organized. This includes the transformation of an eye-antennal imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the eye, antenna, head capsule and maxillary palps. GO:0007454 labial disc morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007454 labial disc metamorphosis The process in which the anatomical structures derived from the labial disc are generated and organized. This includes the transformation of a labial imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including parts of the proboscis. GO:0007453 clypeo-labral disc morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007453 clypeo-labral disc metamorphosis|morphogenesis of structures derived from the clypeo-labral disc The process in which the anatomical structures derived from the clypeo-labral disc are generated and organized. This includes the transformation of a clypeo-labal imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the labrum, anterior and posterior cibarial plates, fish trap bristles, epistomal sclerite and clypeus. GO:0007452 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007452 GO:0007451 dorsal/ventral lineage restriction, imaginal disc biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007451 dorsoventral lineage restriction, imaginal disc|dorsal-ventral lineage restriction, imaginal disc Formation and/or maintenance of a lineage boundary between dorsal and ventral compartments that cells cannot cross, thus separating the populations of cells in each compartment. GO:0007450 dorsal/ventral pattern formation, imaginal disc biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007450 dorsoventral pattern formation, imaginal disc|dorsal-ventral pattern formation, imaginal disc The establishment, maintenance and elaboration of the dorsal/ventral axis of the imaginal disc. Imaginal disks are masses of hypodermic cells, carried by the larvae of some insects after leaving the egg, from which masses the wings and legs of the adult are subsequently formed. CHEBI:79096 1-stearoyl-2-oleoyl-sn-glycero-3-phosphoserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79096 CHEBI:137117 (S)-5-[2-(methylthio)ethyl]hydantoin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137117 CHEBI:79095 N(5)-hydroxy-L-ornithine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79095 CHEBI:137116 N-carbamoyl-L-methioninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137116 CHEBI:79099 1-(1Z-octadecenyl)-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79099 CHEBI:79098 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79098 CHEBI:79097 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79097 CHEBI:137110 17beta-hydroxy-5alpha-estr-1(10)-en-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137110 GO:0032412 regulation of ion transmembrane transporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032412 regulation of ion transporter activity Any process that modulates the activity of an ion transporter. GO:0032411 positive regulation of transporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032411 up regulation of transporter activity|upregulation of transporter activity|stimulation of transporter activity|up-regulation of transporter activity|activation of transporter activity Any process that activates or increases the activity of a transporter. GO:0032410 negative regulation of transporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032410 down-regulation of transporter activity|downregulation of transporter activity|down regulation of transporter activity|inhibition of transporter activity Any process that stops or reduces the activity of a transporter. CHEBI:137112 12-hydroxy-(5Z,8Z,10E,14Z)-icosatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137112 CHEBI:137111 5-hydroxy-(6E,8Z,11Z,14Z)-icosatetraenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137111 GO:0032409 regulation of transporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032409 Any process that modulates the activity of a transporter. GO:0032408 MutSbeta complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032408 Interacting selectively and non-covalently with the mismatch repair complex MutSbeta. GO:0032407 MutSalpha complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032407 Interacting selectively and non-covalently with the mismatch repair complex MutSalpha. GO:0032406 MutLbeta complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032406 Interacting selectively and non-covalently with the mismatch repair complex MutLbeta. GO:0032405 MutLalpha complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032405 Interacting selectively and non-covalently with the mismatch repair complex MutLalpha. GO:0032404 mismatch repair complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032404 Interacting selectively and non-covalently with a mismatch repair complex. GO:0032403 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032403 GO:0007469 antennal development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007469 The process whose specific outcome is the progression of the antenna over time, from its formation to the mature structure. The antenna are the sensory structures on the head that are capable of detecting various environmental stimuli. GO:0032402 melanosome transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032402 The directed movement of melanosomes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0007468 obsolete regulation of rhodopsin gene expression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007468 regulation of rhodopsin gene activity OBSOLETE. Any process that modulates the frequency, rate or extent of rhodopsin gene expression. This includes transcriptional, translational, or posttranslational regulation. GO:0007467 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007467 GO:0007466 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007466 GO:0007465 R7 cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007465 The process in which the R7 photoreceptor commits to its cell fate. The R7 receptor contributes the central part of the rhabdomere in the apical parts of the ommatidium. GO:0007464 R3/R4 cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007464 The process in which the R3/R4 photoreceptors commit to their cell fate. R3 and R4 are paired photoreceptors which contribute the outer rhabdomeres. GO:0007463 R2/R5 cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007463 The process in which the R2/R5 photoreceptors commit to their cell fate. R2 and R5 are paired photoreceptors which contribute the outer rhabdomeres. GO:0007462 R1/R6 cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007462 The process in which the R1/R6 photoreceptors commit to their cell fate. R1 and R6 are paired photoreceptors which contribute the outer rhabdomeres. GO:0007461 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007461 GO:0007460 R8 cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007460 restriction of R8 fate The process in which the R8 photoreceptor commits to its cell fate. The R8 receptor contributes the central part of the rhabdomere in the basal parts of the ommatidium. GO:0007470 prothoracic disc morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007470 prothoracic disc metamorphosis The process in which the anatomical structures derived from the prothoracic disc are generated and organized. This includes the transformation of a prothoracic imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult humerous and anterior spiracle. GO:0032401 establishment of melanosome localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032401 establishment of melanosome localisation The directed movement of a melanosome to a specific location. GO:0032400 melanosome localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032400 melanosome localisation Any process in which a melanosome is transported to, and/or maintained in, a specific location within the cell. GO:0007439 ectodermal digestive tract development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007439 ectodermal gut development The process whose specific outcome is the progression of the ectodermal digestive tract over time, from its formation to the mature structure. The ectodermal digestive tract includes those portions that are derived from ectoderm. GO:0007438 oenocyte development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007438 The process whose specific outcome is the progression of the oenocyte over time, from its formation to the mature structure. The oenocytes are large secretory cells found in clusters underlying the epidermis of larval abdominal segments. GO:0007437 adult salivary gland morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007437 The process in which the anatomical structures of the adult salivary gland are generated and organized. GO:0007436 larval salivary gland morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007436 The process, occurring in the larva, by which the anatomical structures of the salivary gland are generated and organized. GO:0007435 salivary gland morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007435 The process in which the anatomical structures of the salivary gland are generated and organized. GO:0007434 adult salivary gland boundary specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007434 larval salivary gland determination Determination in an adult organism of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland. GO:0007433 larval salivary gland boundary specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007433 larval salivary gland determination Determination in a larval organism of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland. GO:0007432 salivary gland boundary specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007432 salivary gland determination Determination of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland. GO:0007431 salivary gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007431 The process whose specific outcome is the progression of the salivary gland over time, from its formation to the mature structure. Salivary glands include any of the saliva-secreting exocrine glands of the oral cavity. GO:0007430 terminal branching, open tracheal system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007430 terminal branching of trachea, cytoplasmic projection extension Formation of terminal branches in the open tracheal system. These are long cytoplasmic extensions that form fine tubules that transport oxygen directly to the tissues. An example of the process is found in Drosophila melanogaster. GO:0007449 proximal/distal pattern formation, imaginal disc biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007449 The establishment, maintenance and elaboration of the proximal/distal axis of the imaginal disc. Imaginal disks are masses of hypodermic cells, carried by the larvae of some insects after leaving the egg, from which masses the wings and legs of the adult are subsequently formed. GO:0007448 anterior/posterior pattern specification, imaginal disc biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007448 The establishment, maintenance and elaboration of the anterior/posterior axis of the imaginal disc. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that rapidly develop into adult appendages during metamorphosis from larval to adult form. GO:0007447 imaginal disc pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007447 The regionalization process that results in defined areas of the imaginal disc that will undergo specific cell differentaiton. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult appendages (legs, antennae, wings, etc.) during metamorphosis from larval to adult form. GO:0007446 imaginal disc growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007446 The increase in mass of imaginal discs by cell proliferation prior to metamorphosis. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.) during metamorphosis from larval to adult form. GO:0007445 determination of imaginal disc primordium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007445 Allocation of embryonic cells to the imaginal disc founder populations, groups of cells that are committed to contribute to the formation of an imaginal disc compartment. GO:0007444 imaginal disc development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007444 The process whose specific outcome is the progression of the imaginal disc over time, from its formation to the metamorphosis to form adult structures. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.). GO:0007443 Malpighian tubule morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007443 The process in which the anatomical structures of the Malpighian tubule are generated and organized. This process takes place entirely during the embryonic phase. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut. GO:0007442 hindgut morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007442 The process in which the anatomical structures of the hindgut are generated and organized. GO:0007441 anterior midgut (ectodermal) morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007441 The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and organized. CHEBI:127780 phosphonoformic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_127780 GO:0007440 foregut morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007440 The process in which the anatomical structures of the foregut are generated and organized. CHEBI:127781 17-(4-hydroxyphenyl)heptadecanoyl-AMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_127781 CHEBI:137107 5,6-epoxy-(8Z,11Z,14Z)-icosatrienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137107 CHEBI:137106 5-[(9Z)-octadecenoyloxy]octadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137106 CHEBI:137109 (2xi)-3-deoxy-7-O-phospho-beta-D-threo-hept-6-ulopyranosonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137109 CHEBI:137108 5-dehydro-L-gluconate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137108 CHEBI:137103 phosphatidic acid 32:7 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137103 CHEBI:137102 5-[(9Z)-hexadecenoyloxy]octadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137102 GO:0007419 ventral cord development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007419 The process whose specific outcome is the progression of the ventral cord over time, from its formation to the mature structure. The ventral cord is one of the distinguishing traits of the central nervous system of all arthropods (such as insects, crustaceans and arachnids) as well as many other invertebrates, such as the annelid worms. GO:0007418 ventral midline development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007418 The process whose specific outcome is the progression of the ventral midline over time, from its formation to the mature structure. In protostomes (such as insects, snails and worms) as well as deuterostomes (vertebrates), the midline is an embryonic region that functions in patterning of the adjacent nervous tissue. The ventral midline in insects is a cell population extending along the ventral surface of the embryo and is the region from which cells detach to form the ventrally located nerve cords. In vertebrates, the midline is originally located dorsally. During development, it folds inwards and becomes the ventral part of the dorsally located neural tube and is then called the ventral midline, or floor plate. GO:0007417 central nervous system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007417 Wikipedia:Neural_development CNS development The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. GO:0007416 synapse assembly biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0007416 Wikipedia:Synaptogenesis synapse biogenesis|synaptogenesis The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional). GO:0007415 defasciculation of motor neuron axon biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007415 Separation of a motor axon away from a bundle of axons known as a fascicle. GO:0007414 axonal defasciculation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007414 defasciculation of neuron Separation of axons away from a bundle of axons known as a fascicle. GO:0007413 axonal fasciculation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007413 fasciculation of neuron The collection of axons into a bundle of rods, known as a fascicle. GO:0007412 axon target recognition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007412 The process in which an axon recognizes and binds to a set of cells with which it may form stable connections. GO:0007411 axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007411 Wikipedia:Axon_guidance axon growth cone guidance|axon chemotaxis|axon pathfinding The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues. GO:0007410 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007410 GO:0007429 secondary branching, open tracheal system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007429 secondary tracheal branching Sprouting of secondary branches in an open tracheal system. These form from the tips of primary branches and are formed by individual cells that roll up into unicellular tubes. An example of this is found in Drosophila melanogaster. GO:0007428 primary branching, open tracheal system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007428 primary tracheal branching Formation of primary branches in the open tracheal system. These form from small groups of cells that migrate out at specific positions, organizing into tubes as they migrate. An example of this is found in Drosophila melanogaster. GO:0007427 epithelial cell migration, open tracheal system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007427 tracheal cell migration|tracheal epithelial cell migration The orderly movement of epithelial cells during development of an open tracheal system. An example of this is found in Drosophila melanogaster. GO:0007426 tracheal outgrowth, open tracheal system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007426 The projection of branches of an open tracheal system towards their target tissues. An example of this is found in Drosophila melanogaster. GO:0007425 epithelial cell fate determination, open tracheal system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007425 tracheal placode cell fate determination|tracheal epithelial cell fate determination|tracheal cell fate determination The cell fate determination process in which a cell becomes capable of differentiating autonomously into an epithelial cell within an open tracheal system regardless of its environment; upon determination, the cell fate cannot be reversed. Tracheal cells are set aside as 10 clusters of approximately 80 cells on each side of the embryo (termed tracheal placodes). An example of this is found in Drosophila melanogaster. GO:0007424 open tracheal system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007424 The process whose specific outcome is the progression of an open tracheal system over time, from its formation to the mature structure. An open tracheal system is a respiratory system, a branched network of epithelial tubes that supplies oxygen to target tissues via spiracles. An example of this is found in Drosophila melanogaster. GO:0007423 sensory organ development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007423 sense organ development The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure. GO:0007422 peripheral nervous system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007422 The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands. GO:0007421 stomatogastric nervous system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007421 The process whose specific outcome is the progression of the stomatogastric nervous system over time, from its formation to the mature structure. GO:0007420 brain development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007420 The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). CHEBI:31082 2-hydroxy-6-oxonona-2,4,7-trienedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31082 CHEBI:31080 2-hydroxy-2,3-dihydrogenistein biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_31080 CHEBI:31087 2-phytyl-1,4-naphthoquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_31087 CHEBI:79005 diphthine methyl ester residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79005 CHEBI:79008 (R)-nicotinium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79008 CHEBI:79007 tricosanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79007 GO:0032492 detection of molecule of oomycetes origin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032492 detection of oomycetes associated molecule The series of events in which a stimulus from a molecule of oomycetes origin is received and converted into a molecular signal. GO:0032491 detection of molecule of fungal origin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032491 detection of fungal associated molecule|detection of fungus associated molecule The series of events in which a stimulus from a molecule of fungal origin is received and converted into a molecular signal. GO:0032490 detection of molecule of bacterial origin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032490 detection of bacteria associated molecule|detection of bacterium associated molecule|detection of bacterial associated molecule The series of events in which a stimulus from a molecule of bacterial origin is received and converted into a molecular signal. CHEBI:79010 prostaglandin D1(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79010 CHEBI:137198 phosphatidylglycerol 37:4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137198 GO:0032499 detection of peptidoglycan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032499 The series of events in which a peptidoglycan stimulus is received by a cell and converted into a molecular signal. Peptidoglycan is a bacterial cell wall macromolecule. GO:0032498 detection of muramyl dipeptide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032498 The series of events in which a muramyl dipeptide stimulus is received by a cell and converted into a molecular signal. Muramyl dipeptide is derived from peptidoglycan. GO:0032497 detection of lipopolysaccharide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032497 detection of LPS The series of events in which a lipopolysaccharide stimulus is received by a cell and converted into a molecular signal. Lipopolysaccharide is a major component of the cell wall of gram-negative bacteria. CHEBI:137195 phosphatidylglycerol 43:6 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137195 GO:0032496 response to lipopolysaccharide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032496 response to LPS|response to endotoxin Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria. GO:0032495 response to muramyl dipeptide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032495 Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muramyl dipeptide stimulus. Muramyl dipeptide is derived from peptidoglycan. GO:0032494 response to peptidoglycan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032494 Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidoglycan stimulus. Peptidoglycan is a bacterial cell wall macromolecule. GO:0032493 response to bacterial lipoprotein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032493 Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipoprotein stimulus. GO:0032481 positive regulation of type I interferon production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032481 upregulation of type I interferon production|stimulation of type I interferon production|up-regulation of type I interferon production|positive regulation of type I IFN production|activation of type I interferon production|up regulation of type I interferon production Any process that activates or increases the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. GO:0032480 negative regulation of type I interferon production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032480 down regulation of type I interferon production|inhibition of type I interferon production|negative regulation of type I IFN production|down-regulation of type I interferon production|downregulation of type I interferon production Any process that stops, prevents, or reduces the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. CHEBI:79021 (11Z)-3-oxohexadecenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79021 CHEBI:79020 alpha,beta-unsaturated monocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79020 GO:0032489 regulation of Cdc42 protein signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032489 Any process that modulates the frequency, rate or extent of Cdc42 protein signal transduction. GO:0032488 Cdc42 protein signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032488 cdc42 signalling pathway|Cdc42 signaling pathway|Cdc42 signaling A series of molecular signals within the cell that are mediated by the Cdc42 protein switching to a GTP-bound active state. GO:0032487 regulation of Rap protein signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032487 Any process that modulates the frequency, rate or extent of Rap protein signal transduction. GO:0032486 Rap protein signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032486 A series of molecular signals within the cell that are mediated by a member of the Rap family of proteins switching to a GTP-bound active state. GO:0032485 regulation of Ral protein signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032485 Any process that modulates the frequency, rate or extent of Ral protein signal transduction. GO:0032484 Ral protein signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032484 A series of molecular signals within the cell that are mediated by a member of the Ral family of proteins switching to a GTP-bound active state. GO:0032483 regulation of Rab protein signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032483 Any process that modulates the frequency, rate or extent of Rab protein signal transduction. GO:0032482 Rab protein signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032482 A series of molecular signals within the cell that are mediated by a member of the Rab family of proteins switching to a GTP-bound active state. CHEBI:137183 (4Z,7Z,10Z,13Z,16Z,19S,20R)-19,20-epoxydocosapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137183 CHEBI:137182 N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAcl-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc}-Asn residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137182 GO:0032479 regulation of type I interferon production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032479 regulation of type I IFN production Any process that modulates the frequency, rate, or extent of interferon type I production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. CHEBI:137180 2,3-diacyl-alpha-D-glucosaminyl 1-phosphate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137180 CHEBI:80029 epothilone C biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_80029 GO:0032470 positive regulation of endoplasmic reticulum calcium ion concentration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032470 elevation of endoplasmic reticulum calcium ion concentration|elevation of calcium ion concentration in endoplasmic reticulum|elevation of ER calcium ion concentration|endoplasmic reticulum calcium ion concentration elevation Any process that increases the concentration of calcium ions in the endoplasmic reticulum. CHEBI:79034 monacolin J biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79034 CHEBI:79032 O-[S-(dihydromonacolin L carboxy)pantetheine-4'-phosphoryl]-L-serine(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79032 CHEBI:79031 dihydromonacolin L carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79031 GO:0032478 heterotetrameric decaprenyl diphosphate synthase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032478 A heterotetrameric complex located in the mitochondrial inner membrane that possesses di-trans,poly-cis-decaprenylcistransferase activity; involved in ubiquinone biosynthesis. In S. pombe it is a heterotetramer of Dlp1 and Dps1. CHEBI:79038 mevinolinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79038 GO:0032477 homodimeric decaprenyl diphosphate synthase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032477 A homodimeric complex that possesses di-trans,poly-cis-decaprenylcistransferase activity; involved in ubiquinone biosynthesis. GO:0032476 decaprenyl diphosphate synthase complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0032476 A complex that possesses di-trans,poly-cis-decaprenylcistransferase activity; involved in ubiquinone biosynthesis. CHEBI:79036 3alpha-hydroxy-3,5-dihydromonacolin L carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79036 GO:0032475 otolith formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032475 The process that gives rise to an otolith. This process pertains to the initial formation of a structure from unspecified parts. CHEBI:79035 monacolin J carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79035 GO:0032474 otolith morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032474 The process in which the anatomical structures of an otolith are generated and organized. GO:0032473 cytoplasmic side of mitochondrial outer membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032473 external side of mitochondrial outer membrane|external side of mitochondrial envelope|cytosolic side of mitochondrial outer membrane|external leaflet of mitochondrial outer membrane The external (cytoplasmic) face of the mitochondrial outer membrane. CHEBI:137179 UDP-2,3-diacyl-alpha-D-glucosamine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137179 GO:0032472 Golgi calcium ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032472 Golgi calcium transport The directed movement of calcium ions (Ca2+) into, out of or within the Golgi apparatus. GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032471 reduction of ER calcium ion concentration|endoplasmic reticulum calcium ion concentration reduction|ER calcium ion concentration reduction|reduction of endoplasmic reticulum calcium ion concentration|reduction of calcium ion concentration in endoplasmic reticulum|reduction of calcium ion concentration in ER Any process that decreases the concentration of calcium ions in the endoplasmic reticulum. PR:000021742 thyrotropin subunit beta proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000021742 TSHB/ClvPrd A thyrotropin subunit beta that has been processed by proteolytic cleavage. CHEBI:137193 (5Z,11Z,14Z,17Z)-8,9-epoxyicosatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137193 GO:0032469 endoplasmic reticulum calcium ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032469 regulation of ER calcium ion concentration|regulation of endoplasmic reticulum calcium ion concentration|ER calcium ion concentration regulation|endoplasmic reticulum calcium ion concentration regulation|regulation of calcium ion concentration in ER|calcium ion homeostasis in endoplasmic reticulum|ER calcium ion homeostasis|calcium ion homeostasis in ER|regulation of calcium ion concentration in endoplasmic reticulum Any process involved in the maintenance of an internal steady state of calcium ions within the endoplasmic reticulum of a cell or between the endoplasmic reticulum and its surroundings. GO:0032468 Golgi calcium ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032468 regulation of calcium ion concentration in Golgi|regulation of Golgi calcium ion concentration|calcium ion homeostasis in Golgi|Golgi calcium ion concentration regulation Any process involved in the maintenance of an internal steady state of calcium ions within the Golgi apparatus of a cell or between the Golgi and its surroundings. CHEBI:79044 monacolin L carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79044 CHEBI:137187 15(S)-HPETE 2-glyceryl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137187 GO:0032467 positive regulation of cytokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032467 up regulation of cytokinesis|activation of cytokinesis|stimulation of cytokinesis|positive regulation of cell cycle cytokinesis|up-regulation of cytokinesis|upregulation of cytokinesis Any process that activates or increases the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells. CHEBI:79049 L-glucopyranuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79049 CHEBI:137186 N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-[beta-D-Xyl-(1->2)]-beta-D-Man-(1->4)-beta-D-GlcNAcl-(1->4)-beta-D-GlcNAc}-Asn residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137186 GO:0032466 negative regulation of cytokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032466 down-regulation of cytokinesis|negative regulation of cell cycle cytokinesis|inhibition of cytokinesis|down regulation of cytokinesis|downregulation of cytokinesis Any process that stops, prevents, or reduces the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells. CHEBI:79048 L-glucuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79048 GO:0032465 regulation of cytokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032465 regulation of cell cycle cytokinesis Any process that modulates the frequency, rate or extent of the division of the cytoplasm of a cell and its separation into two daughter cells. CHEBI:137185 PA(18:0/18:3) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137185 CHEBI:79047 D-mannopyranuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79047 GO:0032464 positive regulation of protein homooligomerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032464 activation of protein homooligomerization|stimulation of protein homooligomerization|up-regulation of protein homooligomerization|upregulation of protein homooligomerization|induction of protein homooligomerization|up regulation of protein homooligomerization Any process that activates or increases the frequency, rate or extent of protein homooligomerization. GO:0032463 negative regulation of protein homooligomerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032463 down-regulation of protein homooligomerization|inhibition of protein homooligomerization|down regulation of protein homooligomerization|downregulation of protein homooligomerization Any process that stops, prevents, or reduces the frequency, rate or extent of protein homooligomerization. GO:0032462 regulation of protein homooligomerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032462 Any process that modulates the frequency, rate or extent of protein homooligomerization. GO:0032461 positive regulation of protein oligomerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032461 up-regulation of protein oligomerization|upregulation of protein oligomerization|induction of protein oligomerization|up regulation of protein oligomerization|activation of protein oligomerization|stimulation of protein oligomerization Any process that activates or increases the frequency, rate or extent of protein oligomerization. GO:0032460 negative regulation of protein oligomerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032460 inhibition of protein oligomerization|down regulation of protein oligomerization|downregulation of protein oligomerization|down-regulation of protein oligomerization Any process that stops, prevents, or reduces the frequency, rate or extent of protein oligomerization. GO:0032459 regulation of protein oligomerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032459 Any process that modulates the frequency, rate or extent of protein oligomerization. GO:0032458 slow endocytic recycling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032458 The directed movement of membrane-bounded vesicles from deep (non-peripheral) compartments endocytic compartments back to the plasma membrane where they are recycled for further rounds of transport. GO:0032457 fast endocytic recycling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032457 direct endocytic recycling The directed movement of membrane-bounded vesicles from peripheral endocytic compartments back to the plasma membrane where they are recycled for further rounds of transport. GO:0007499 ectoderm and mesoderm interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007499 ectoderm/mesoderm interaction A cell-cell signaling process occurring between the two gastrulation-generated layers of the ectoderm and the mesoderm. GO:0007498 mesoderm development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007498 The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue. GO:0007497 posterior midgut development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007497 The process whose specific outcome is the progression of the posterior midgut over time, from its formation to the mature structure. GO:0007496 anterior midgut development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007496 The process whose specific outcome is the progression of the anterior midgut over time, from its formation to the mature structure. GO:0007495 visceral mesoderm-endoderm interaction involved in midgut development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007495 visceral mesoderm/endoderm interaction The process of cell-cell signaling between visceral mesoderm cells and endoderm cells that is involved in the differentiation of cells in the midgut. GO:0007494 midgut development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007494 The process whose specific outcome is the progression of the midgut over time, from its formation to the mature structure. The midgut is the middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine. GO:0007493 endodermal cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007493 endoderm cell fate determination The cell fate determination process in which a cell becomes capable of differentiating autonomously into an endoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed. CHEBI:79056 plasticiser biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79056 CHEBI:79054 D-arabinofuranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79054 GO:0032456 endocytic recycling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032456 retrograde transport of endocytic vesicles The directed movement of membrane-bounded vesicles from recycling endosomes back to the plasma membrane where they are recycled for further rounds of transport. CHEBI:137154 (4Z,7Z,10Z,13Z,16Z,19R,20S)-19,20-epoxydocosapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137154 GO:0032455 nerve growth factor processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032455 NGF processing|beta-nerve growth factor processing The generation of a mature nerve growth factor (NGF) by proteolysis of a precursor. CHEBI:79059 2-arachidonoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79059 GO:0032454 histone demethylase activity (H3-K9 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032454 Reactome:R-HSA-997263|Reactome:R-HSA-9011949|EC:1.14.11.66|EC:1.14.11.65|Reactome:R-HSA-9011985 Catalysis of the reaction: histone H3 N6-methyl-L-lysine (position 9) + alpha-ketoglutarate + O2 = succinate + CO2 + formaldehyde + lysine. This reaction is the removal of a methyl group from lysine at position 9 of the histone H3 protein. CHEBI:137152 N-carbamoyl-D-methioninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137152 CHEBI:79058 D-arabinose 5-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79058 GO:0032453 histone demethylase activity (H3-K4 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032453 Catalysis of the removal of a methyl group from lysine at position 4 of the histone H3 protein. CHEBI:79057 hercynylcysteine sulfoxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79057 GO:0032452 histone demethylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032452 Reactome:R-HSA-5661123|Reactome:R-HSA-5661122|Reactome:R-HSA-4722133|Reactome:R-HSA-5625870|Reactome:R-HSA-4754187|Reactome:R-HSA-4754181|Reactome:R-HSA-5625848|Reactome:R-HSA-5661125|Reactome:R-HSA-5661124|Reactome:R-HSA-4724284|Reactome:R-HSA-5661116|Reactome:R-HSA-5661120|Reactome:R-HSA-4724279|Reactome:R-HSA-5423117|Reactome:R-HSA-4754176|Reactome:R-HSA-5625797|Reactome:R-HSA-3214912|Reactome:R-HSA-5661114|Reactome:R-HSA-5661121|Reactome:R-HSA-5661115 Catalysis of the removal of a methyl group from a histone. GO:0032451 demethylase activity biolink:MolecularActivity go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0032451 Catalysis of the removal of a methyl group from a substrate. GO:0032450 maltose alpha-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032450 EC:3.2.1.20|MetaCyc:RXN-2141 maltase activity Catalysis of the reaction: alpha-maltose + H2O = 2 alpha-D-glucose. CHEBI:137156 phosphatidylserine(18:1/18:2) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137156 CHEBI:137155 phosphatidylserine 36:3 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137155 GO:0032449 CBM complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032449 CARMA1-BCL10-Malt1 complex A protein complex comprising Carma1, Bcl10 and MALT1; plays a role in signal transduction during NF-kappaB activation. CHEBI:137172 prostaglandin E2 2-glyceryl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137172 GO:0032448 DNA hairpin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032448 Interacting selectively and non-covalently with DNA containing a hairpin. A hairpin structure forms when a DNA strand folds back on itself and intrachain base pairing occurs between inverted repeat sequences. GO:0032447 protein urmylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032447 Covalent attachment of the ubiquitin-like protein URM1 to another protein. GO:0032446 protein modification by small protein conjugation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032446 A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to a target protein. CHEBI:79070 hercynylselenocysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79070 CHEBI:79063 4,4'-diapolycopenedioate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79063 CHEBI:79067 1-hexanoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79067 CHEBI:79066 4-O-beta-D-glucosyl-trans-4-coumarate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79066 CHEBI:79065 4,4'-diaponeurosporenal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79065 CHEBI:79064 4,4'-diaponeurosporenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79064 CHEBI:137165 (S)-6-acetamido-3-aminohexanoic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137165 GO:0032445 fructose import biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032445 fructose uptake The directed movement of the hexose monosaccharide fructose into a cell or organelle. CHEBI:137164 phosphatidic acid 36:3 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137164 GO:0032444 activin responsive factor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032444 ARF complex A transcriptionally active complex that binds to an activin response element (ARE) in the promoter of target genes, and is composed of two SMAD2 proteins, one SMAD4 protein and a Forkhead activin signal transducer (FAST) transcription factor. GO:0032443 regulation of ergosterol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032443 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol. GO:0032442 phenylcoumaran benzylic ether reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032442 PCBER activity Catalysis of the NADPH-dependent 7-O-4' reduction of phenylcoumaran lignans to the corresponding diphenols; for example, catalysis of the reaction: dehydrodiconiferyl alcohol + NADPH + H+ = isodihydrodehydrodiconiferyl alcohol + NADP+. CHEBI:79068 crocin-1 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79068 GO:0032441 pheophorbide a oxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032441 EC:1.14.15.17|MetaCyc:RXN-7740|RHEA:48140 Catalysis of the reaction: pheophorbide a + reduced ferredoxin + 2 O2 = red chlorophyll catabolite + oxidized ferredoxin + H2O. CHEBI:137169 alpha-D-mannosyl-(1->3)-alpha-D-mannosyl-(1->3)-alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-1-diphospho-ditrans,polycis-undecaprenol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137169 CHEBI:137168 alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-1-diphospho-ditrans,polycis-undecaprenol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137168 GO:0032440 2-alkenal reductase [NAD(P)+] activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032440 EC:1.3.1.74 n-alkanal:NAD(P)+ 2-oxidoreductase activity|NAD(P)H-dependent alkenal/one oxidoreductase activity Catalysis of the reaction: n-alkanal + NAD(P)+ = alk-2-enal + NAD(P)H + H+. CHEBI:137167 16(S)-HETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137167 CHEBI:137166 16(R)-HETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137166 CHEBI:21650 N-acyl-L-glutamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21650 CHEBI:21652 N-acyl-O-acetylneuraminic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21652 CHEBI:21655 N-acylgalactosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21655 UBERON:0016481 bronchial lymph node biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016481 A lymph node that is part of a bronchus. CHEBI:21654 N-acyl-aspartic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21654 GO:0140346 phosphatidylserine flippase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140346 phosphatidylserine flippase activity (exoplasmic to cytosolic leaftlet) Catalysis of the movement of phosphatidylserine from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP. GO:0140345 phosphatidylcholine flippase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140345 phosphatidylcholine flippase activity (exoplasmic to cytosolic leaftlet) Catalysis of the movement of phosphatidylcholine from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP. GO:0140348 lysophosphatidylcholine flippase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140348 lysophosphatidylcholine flippase activity (exoplasmic to cytosolic leaftlet) Catalysis of the movement of lysophosphatidylcholine from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP. GO:0140347 N-retinylidene-phosphatidylethanolamine flippase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140347 N-retinylidene-phosphatidylethanolamine flippase activity (exoplasmic to cytosolic leaftlet) Catalysis of the movement of N-retinylidene-N-retinylphosphatidylethanolamine from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP. GO:0140340 cerebroside transfer activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140340 cerebroside carrier activity Directly binding to a cerebroside and delivering it either to an acceptor molecule or to a specific location. GO:0140341 phosphatidylethanolamine floppase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140341 phosphatidylethanolamine floppase activity (cytosolic to exoplasmic leaftlet) Catalysis of the movement of phosphatidylethanolamine from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP. GO:0140344 triglyceride transfer activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140344 triglyceride carrier activity Directly binding to a triglyceride and delivering it either to an acceptor molecule or to a specific location. GO:0140343 phosphatidylserine transfer activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140343 intermembrane phosphatidylserine carrier activity Removes phosphatidylserine from the outer leaflet of a donor membrane, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to the outer leaflet of an acceptor membrane. CHEBI:21656 N-acyl-hexosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21656 CHEBI:21658 N-acylglutamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21658 CHEBI:21662 N-acylneuraminic acid phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21662 CHEBI:21663 N-acylneuraminates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21663 GO:0140334 lipopolysaccharide localization to cell outer membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140334 LPS localization to cell outer membrane A process in which a lipopolysaccharide is transported to the cell outer membrane. GO:0140337 diacylglyceride transfer activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140337 diacylglyceride carrier activity Directly binding to diacylglyceride and delivering it either to an acceptor molecule or to a specific location. GO:0140339 phosphatidylglycerol transfer activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140339 phosphatidylglycerol carrier activity Directly binding to phosphatidylglycerol and delivering it either to an acceptor molecule or to a specific location. GO:0140338 sphingomyelin transfer activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140338 sphingosine transmembrane transporter activity|sphingomyelin carrier activity Removes a sphingomyelin from the outer leaflet of a donor membrane, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to the outer leaflet of an acceptor membrane. UBERON:0016479 capsule of liver biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016479 glisson's capsule|fibrous capsule of liver|tunica fibrosa hepatis|tunica fibrosa (hepar)|liver capsule|fibrous capsule of Glisson|hepatic capsule|capsula fibrosa perivascularis A collagenous capsule covering the external surface of the liver. UBERON:0016478 liver stroma biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016478 hepatic stroma|stroma of liver A stroma that is part of a liver. GO:0140331 aminophospholipid translocation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140331 The movement of an aminophospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet. GO:0140330 xenobiotic detoxification by transmembrane export across the cell outer membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140330 A process that reduces or removes the toxicity of a xenobiotic by exporting it outside the cell through the outer membrane. CHEBI:45616 (R)-1-phenylethanol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_45616 GO:0140333 glycerophospholipid flippase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140333 glycerophospholipid flippase activity (exoplasmic to cytosolic leaftlet) Catalysis of the movement of a glycerophospholipid from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP. GO:0140332 lipopolysaccharide transfer activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140332 lipopolysaccharide carrier activity|intermembrane lipopolysaccharide transporter activity|intermembrane lipopolysaccharide transfer activity|intermembrane LPS transporter activity Removes a lipopolysaccharide (LPS) from the outer leaflet of a donor membrane, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to the outer leaflet of an acceptor membrane. CHEBI:21668 N-alanyl-glycosylphosphatidylinositolethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21668 GO:0140368 decoy receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140368 osteoclastogenesis inhibitory factor|osteoprotegerin complex A receptor complex that recognizes, binds and sequesters a specific receptor ligand to prevent it from binding to its regular receptor. May be soluble or membrane bound. GO:0140367 antibacterial innate immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140367 An defense response against a bacteria mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens. GO:0140360 cyclic-GMP-AMP transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140360 Enables the transfer of cyclic-GMP-AMP from one side of a membrane to the other. GO:0140362 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0140362 GO:0140361 cyclic-GMP-AMP transmembrane import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140361 The directed movement of cyclic-GMP-AMP from outside of a cell, across the plasma membrane and into the cytosol. GO:0140364 GW body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140364 GW-body A ribonucleoprotein granule located in the cytoplasm and the nucleus. GW-bodies minimally contain the Argonaute2 (Ago2) and TNRC6B proteins, together with specific target RNAs. GO:0140363 TIS granule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140363 A ribonucleoprotein granule located in the cytoplasm that is formed by the RNA-binding protein TIS11B and RNA molecules, enriched in membrane protein-encoding mRNAs with multiple AU-rich elements. TIS granules are reticular meshworks intertwined with the endoplasmic reticulum (ER). GO:0140366 galectin lattice biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140366 A non-stoichiometric protein complex formed by several galectins crosslinking glycosylated ligands to form a dynamic lattice. The galectin lattice modulates receptor kinase signaling and the functionality of membrane receptors, by regulating the diffusion, compartmentalization and endocytosis of plasma membrane glycoproteins and glycolipids. GO:0140365 RNP body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140365 BR-body A ribonucleoprotein granule located in the cytoplasm of bacteria, minimally containing the RNase E protein and RNA molecules. Bacterial RNP-bodies are similar to eukaryotic P-bodies and stress granules. CHEBI:21635 N-acyl-D-glucosamine 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21635 CHEBI:21637 N-acyl-D-glucosamine phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21637 CHEBI:21638 N-acylglucosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21638 CHEBI:21644 N-acyl-L-amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21644 GO:0140357 heme export from vacuole to cytoplasm biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140357 The directed movement of heme from inside the vacuole across the vacuolar membrane and into the cytosol. UBERON:0016458 esophageal hiatus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016458 esophageal hiatus of diaphragm|oesophageal hiatus|oesophageal aperture A hole in the diaphragm through which the esophagus passes GO:0140359 ABC-type transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140359 Reactome:R-HSA-5362459|Reactome:R-HSA-5387389|Reactome:R-HSA-9661405|Reactome:R-HSA-5683325|Reactome:R-HSA-5223313|Wikipedia:ATP-binding_cassette_transporter|TC:3.A.1|Reactome:R-HSA-266070 ABC transporter|ABC-type efflux permease activity|ATP binding cassette transporter|ABC-type uptake permease activity|ABC-type efflux porter activity|ATP-binding cassette (ABC) transporter activity|ATP-binding cassette transporter|ABC-type transmembrane transporter activity Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane. GO:0140358 P-type transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140358 TC:3.A.3|Wikipedia:P-type_ATPase P-type ATPase|E1-E2 ATPase Primary active transporter that auto-phosphorylates (hence P) at a key conserved aspartate residue, generating a conformational change that allows transport of the substrate. Hydrolysis of the phosphorylated Asp residue, catalyzed by the actuator (A) domain, results in another state with occluded substrates. Upon dissociation of Mg2+ and inorganic phosphate (Pi), the enzyme reverts to the initial state, in which the counter-transported substrate is released into the cytosol. GO:0140351 glycosylceramide flippase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140351 glycoceramide flippase activity|galactosylceramide flippase activity|glycosylceramide flippase activity (exoplasmic to cytosolic leaftlet)|glucosylceramide flippase activity|galactocerebroside flippase activity Catalysis of the movement of glycosylceramide from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP. Glycosylceramides are ceramides containing a functional group derived from a sugar. GO:0140353 lipid export from cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140353 lipid efflux The directed movement of a lipid from a cell, into the extracellular region. GO:0140352 export from cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140352 efflux The directed movement of some substance from a cell, into the extracellular region. This may occur via transport across the plasma membrane or via exocytosis. GO:0140355 cargo receptor ligand activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140355 cargo The activity of a gene product that interacts with a cargo receptor and initiates endocytosis. GO:0140354 lipid import into cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140354 lipid uptake The directed movement of a lipid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis. CHEBI:21645 N-acyl-L-arginine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21645 CHEBI:21647 N-acyl-L-aspartic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21647 GO:0140302 pollen-style interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140302 The interactions (or cell to cell communication) that occur between the male gametophyte (pollen/pollen tube) and the stylar tissues of the female sporophyte. GO:0140301 pollen-stigma interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140301 The interactions (or cell to cell communication) that occur between the pollen grain (male gametophyte) and the stigmatic tissues of the female sporophyte after the pollen reaches the stigmatic papillae. GO:0140303 intramembrane lipid transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140303 translocase activity|flippase activity Enables the transport of a lipid from a region of a membrane to a different region on the same membrane. GO:0140306 lipoprotein releasing activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140306 The activity of recognizing mature outer membrane lipoproteins in the inner membrane and releasing from the inner membrane so that they can be transported across the periplasmic space to their target location, the outer membrane. This function exists in diderm bacteria, mediated by the LolCDE complex. GO:0140300 serine import into mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140300 The process in which serine is transported from the cytosol, into the mitochondrial matrix. CHEBI:21615 N-acetyl-D-muramic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21615 UBERON:6007280 embryonic/larval head sense organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_6007280 larval head sense organ Any sense organ (UBERON:6005155) that is part of some larval head (UBERON:6001730). CHEBI:21619 N-acetylneuraminates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21619 CHEBI:21622 N-acetylneuraminic acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21622 CHEBI:3638 chloroquine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_3638 CHEBI:21626 N-acetylphenylalanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21626 GO:0140323 solute:anion antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140323 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion(in) + solute(out) = anion(out) + solute(in). GO:0140326 ATPase-coupled intramembrane lipid transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140326 EC:7.6.2.1|Reactome:R-HSA-939763|Reactome:R-HSA-947591|MetaCyc:3.6.3.1-RXN ATPase-dependent phospholipid transporter activity|phospholipid translocating ATPase activity|aminophospholipid-transporting ATPase|phospholipid flippase activity|phospholipid-translocating ATPase activity|phospholipid-transporting ATPase activity|ATPase-coupled phospholipid transporter activity Catalysis of the movement of lipids from one membrane leaflet to the other, using energy from the hydrolysis of ATP. This includes flippases and floppases. GO:0140325 negative regulation of protein localization to medial cortex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140325 Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to the medial cortex. GO:0140328 floppase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140328 floppase activity (cytosolic to exoplasmic leaftlet) Catalysis of the movement of a lipid from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP. GO:0140327 flippase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140327 flippase activity (exoplasmic to cytosolic leaftlet) Catalysis of the movement of lipids from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP. GO:0140329 lysophospholipid translocation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140329 The movement of a lysophospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet. GO:0140320 PAMP receptor decoy activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140320 pathogen-associated molecular pattern receptor decoy activity|pattern recognition receptor decoy activity A gene product which recognizes, binds and sequesters PAMP ligands in order to prevent them from binding and activating to the host PAMP receptor. Usually this activity is encoded by a symbiont or a pathogen to prevent activation of the host innate immune response. GO:0140321 negative regulation by symbiont of host autophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140321 Any process in which a symbiont organism decreases the frequency, rate or extent of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction. UBERON:0016490 auditory system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016490 is the sensory system for the sense of hearing. OBO:chebi#is_enantiomer_of is enantiomer of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/chebi#is_enantiomer_of GO:0140313 molecular sequestering activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140313 The selective interaction of a protein with a specific molecule to prevent it from interacting with other partners or inhibiting its localization to other areas of the cell. GO:0140312 cargo adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140312 endocytic adaptor activity Binding directly to the structural scaffolding elements of a vesicle coat (such as clathrin or COPII), and bridging the membrane, cargo receptor, and membrane deformation machinery. GO:0140315 iron ion sequestering activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140315 The selective interaction of a protein with an iron ion to prevent it from interacting with other partners or inhibiting its localization to other areas of the cell. GO:0140314 calcium ion sequestering activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140314 The selective interaction of a protein with a calcium ion to prevent it from interacting with other partners or inhibiting its localization to other areas of the cell. GO:0140317 export across cell outer membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140317 The directed movement of a substance across the outer membrane in cells with two membranes. GO:0140316 obsolete vesicular transport adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140316 OBSOLETE. Binding directly to sorting signals in the cytosolic tails of transmembrane cargos (or transmembrane cargo receptors serving as recognition interfaces for lumenal cargos), to concentrate them into vesicles or tubules for transport via intracellular vesicular transport or the secretory pathway. GO:0140319 receptor decoy activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140319 decoy death receptor activity|decoy receptor Recognizing, binding and sequestering a specific receptor ligand to prevent it from binding to its regular receptor. GO:0140318 protein transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140318 Reactome:R-HSA-9662818|Reactome:R-HSA-9662747 protein carrier activity|protein transport chaperone Directly binding to a specific protein and delivering it to a specific cellular location. GO:0140311 protein sequestering activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140311 The selective interaction of a protein with a specific protein, to prevent it from interacting with other partners or inhibiting its localization to other areas of the cell. CHEBI:21601 N-acetyl-D-hexosamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_21601 UBERON:0016405 pulmonary capillary biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016405 capillary of lung A capillary that is part of a lung. UBERON:0016400 infrapatellar fat pad biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016400 The infrapatellar fat pad, also known as Hoffa's fat pad, is a cylindrical piece of fat that is situated under and behind the patella bone within the knee. CHEBI:3663 cholesteryl palmitate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_3663 CHEBI:31059 13-dihydrodaunorubicin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31059 CHEBI:31058 (13R)-13-dihydrocarminomycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31058 CHEBI:31057 13-deoxydaunorubicin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31057 CHEBI:31056 13-deoxycarminomycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31056 GO:0071990 maintenance of protein location to spindle pole body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071990 maintenance of protein location at spindle pole body|maintenance of protein location in spindle pole body Any process in which a protein is maintained in a specific location at the spindle pole body, and is prevented from moving elsewhere. GO:0007409 axonogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007409 axon growth|axon morphogenesis|neuron long process generation De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells. GO:0007408 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007408 GO:0007407 neuroblast activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007407 A change in the morphology or behavior of a neuroblast resulting from exposure to an activating factor such as a cellular or soluble ligand. GO:0007406 negative regulation of neuroblast proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007406 down-regulation of neuroblast proliferation|suppression of neuroblast proliferation|downregulation of neuroblast proliferation|down regulation of neuroblast proliferation|inhibition of neuroblast proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of the proliferation of neuroblasts. GO:0007405 neuroblast proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007405 The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron. GO:0007404 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007404 GO:0007403 glial cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007403 The cell fate determination process in which a cell becomes capable of differentiating autonomously into a glial cell regardless of its environment; upon determination, the cell fate cannot be reversed. GO:0007402 ganglion mother cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007402 The cell fate determination process in which a cell becomes capable of differentiating autonomously into a ganglion mother cell regardless of its environment; upon determination, the cell fate cannot be reversed. GO:0007401 obsolete pan-neural process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007401 pan-neural process OBSOLETE. (Was not defined before being made obsolete). GO:0007400 neuroblast fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007400 neuroblast identity determination|neuroblast cell fate determination The cell fate determination process in which a cell becomes capable of differentiating autonomously into a neuroblast cell regardless of its environment; upon determination, the cell fate cannot be reversed. An example of this process is found in Mus musculus. CHEBI:45696 hydrogensulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_45696 GO:0071999 extracellular polysaccharide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071999 extracellular polysaccharide breakdown|extracellular polysaccharide catabolism|extracellular polysaccharide degradation The chemical reactions and pathways resulting in the breakdown of polysaccharides used in extracellular structures. GO:0071998 ascospore release from ascus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071998 ascospore liberation A developmental process that results in the discharge of ascospores from the ascus. Ascospore release may be active or passive. GO:0071997 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0071997 GO:0071996 glutathione transmembrane import into vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071996 glutathione transport into vacuole The directed movement of glutathione into the vacuole across the vacuolar membrane. CHEBI:31069 2,3,5-trichloro-cis,cis-muconic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31069 GO:0071995 phytochelatin import into vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071995 cadystin import into vacuole|phytochelatin transport into vacuole The directed movement of phytochelatins into the vacuole. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. GO:0071994 phytochelatin transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071994 cadystin transmembrane transport|phytochelatin membrane transport The process in which a phytochelatin is transported across a membrane. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. GO:0071993 phytochelatin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071993 cadystin transport The directed movement of a phytochelatin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. GO:0071992 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0071992 GO:0071991 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0071991 NCBITaxon:8457 Sauropsida organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_8457 sauropsids CHEBI:31047 10-carboxy-13-deoxycarminomycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31047 UBERON:0016442 median palatine suture biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016442 midpalatal suture of skull|median palatine suture of skull|middle palatine suture of skull the line of junction between the horizontal parts of the palatine bones that extends from both sides of the skull to form the posterior part of the hard palate. CHEBI:21698 N-cysteinyl-glycosylphosphatidylinositolethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21698 UBERON:0016447 hair of trunk biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016447 trunk hair A strand of hair that is part of a trunk. UBERON:0016446 hair of head biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016446 hair of scalp|head hair A strand of hair that is part of a head. GO:0140382 tryptamine 4-monooxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140382 RHEA:15865|EC:1.14.99.59 Catalysis of the reaction: tryptamine + reduced acceptor + O(2) <=> 4-hydroxytryptamine + acceptor + H(2)O. GO:0140381 4-hydroxytryptamine 4-phosphate methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140381 RHEA:55568|EC:2.1.1.345 norbaeocystin methyltransferase|psilocybin synthase Catalysis of the reaction: 2 S-adenosyl-L-methionine (SAM) + 4-hydroxytryptamine 4-phosphate (norbaeocystin) <=> 2 S-adenosyl-L-homocysteine + psilocybin. GO:0140384 metacyclogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140384 The morphological, biochemical and genetic changes that induce the differentiation of non-pathogenic parasites into pathogenic metacyclic parasites in the Trypanosomatidae species. The pathogenic parasites are known as metacyclic trypomastigotes in Trypanosoma and metacyclic promastigotes in Leishmania. GO:0140383 4-hydroxytryptamine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140383 RHEA:55564|EC:2.7.1.222 Catalysis of the reaction: 4-hydroxytryptamine + ATP = 4-hydoxytryptamine 4-phosphate + ADP + H(+). CHEBI:31014 tetracosanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_31014 CHEBI:31013 cerotate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_31013 CHEBI:31011 valerate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_31011 GO:0140380 psilocybin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140380 The chemical reactions and pathways resulting in the formation of psilocybin, a psychotropic tryptamine-derived natural product. UBERON:0016435 chest wall biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016435 Subdivision of thorax which includes all structures from the skin to the costal pleura. Examples: There is only one chest wall. GO:0140373 histone H3-K14 ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140373 histone H3-K14 ubiquitylation|histone H3 ubiquitination at K14|histone H3K14 ubiquitination The modification of histone H3 by the addition of one or more ubiquitin groups to a lysine residue at position 14 of the histone. GO:0140372 histone H3 ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140372 histone H3 ubiquitylation The modification of histone H3 by the addition of one or more ubiquitin groups. GO:0140375 immune receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140375 Receiving a signal and transmitting it in a cell to initiate an immune response. GO:0140374 antiviral innate immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140374 A defense response against viruses mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens. GO:0140376 innate immune receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140376 Receiving a signal and transmitting it in a cell to initiate an innate immune response. CHEBI:583099 ent-zingiberene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_583099 CHEBI:21672 N-amidino-amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21672 CHEBI:21675 N-asparaginyl-glycosylphosphatidylinositolethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21675 CHEBI:21676 N-aspartyl-glycosylphosphatidylinositolethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21676 CHEBI:21681 N-benzoyl-D-arginines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21681 CHEBI:31009 hexacosanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31009 CHEBI:21686 N-carbamoyl-L-amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21686 UBERON:0016410 male breast biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016410 mamma masculina A breast that is part of a male organism. CHEBI:45630 4-oxopentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_45630 GO:0140393 norsolorinic acid ketoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140393 MetaCyc:RXN-9480|EC:1.1.1.349|KEGG_REACTION:R10309|RHEA:35447 Catalysis of the reaction: (1'S)-averantin + NADP(+) <=> norsolorinic acid + NADPH. NCBITaxon:8492 Archosauria organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_8492 GO:0140395 averantin hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140395 MetaCyc:RXN-9482|RHEA:35575|EC:1.14.14.116 Catalyzes the reaction: (1'S)-averantin + [reduced NADPH--hemoprotein reductase] + O(2) <=> (1'S,5'S)-5'-hydroxyaverantin + [oxidized NADPH--hemoprotein reductase] + H(2)O. Involved in aflatoxin biosynthesis. GO:0140394 ABC-type azole transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140394 RHEA:33503 azole ABC transporter activity|ATPase-coupled azole transmembrane transporter activity Enables the transfer of azoles, heterocyclic compound found in many biologically important substances, from one side of a membrane to the other according to the reaction: ATP + H2O + azole(in) = ADP + phosphate + azole(out). GO:0140397 versiconal hemiacetal acetate esterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140397 EC:3.1.1.94|MetaCyc:RXN-9493|MetaCyc:RXN-9488|RHEA:35715 Catalyzes the reactions: versiconal hemiacetal acetate + H(2)O <=> versiconal + acetate, as well as versiconol acetate + H(2)O <=> versiconol + acetate. GO:0140396 5'-hydroxyaverantin dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140396 RHEA:35475|EC:1.1.1.352 Catalyzes the reaction: (1'S,5'S)-hydroxyaverantin + NAD(+) <=> 5'-oxoaverantin + NADH. GO:0140399 aflatoxin B synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140399 EC:1.14.14.117|MetaCyc:RXN-9502|RHEA:35759|MetaCyc:RXN-9497 Catalyzes the reaction: 8-O-methylsterigmatocystin + 2 [reduced NADPH--hemoprotein reductase] + 2 O(2) <=> aflatoxin B + 2 [oxidized NADPH--hemoprotein reductase] + H(2)O + methanol + CO(2). Produces both aflatoxin B(1) and aflatoxin B(2). GO:0140398 versicolorin B desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140398 MetaCyc:RXN-9495|RHEA:35743|KEGG_REACTION:R10479 Catalyzes the reaction: versicolorin B + NADPH + O(2) <=> versicolorin A + NADP(+) + 2 H(2)O. Uses heme-thiolate as a co-factor. Involved in the synthesis of aflatoxins in the fungus Aspergillus parasiticus. CHEBI:31004 triacontanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_31004 CHEBI:21689 N-carbamoyl-amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21689 CHEBI:31003 triacontanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31003 CHEBI:31002 octacosanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_31002 CHEBI:31001 octacosanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31001 GO:0032559 adenyl ribonucleotide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032559 Interacting selectively and non-covalently with an adenyl ribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety. CHEBI:137260 omega-[(methylsulfinyl)alkyl]glucosinolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137260 GO:0032558 adenyl deoxyribonucleotide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032558 Interacting selectively and non-covalently with an adenyl deoxyribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety. GO:0032557 pyrimidine ribonucleotide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032557 Interacting selectively and non-covalently with a pyrimidine ribonucleotide, any compound consisting of a pyrimidine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety. GO:0032556 pyrimidine deoxyribonucleotide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032556 Interacting selectively and non-covalently with a pyrimidine deoxyribonucleotide, any compound consisting of a pyrimidine deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety. GO:0007599 hemostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007599 Wikipedia:Hemostasis The stopping of bleeding (loss of body fluid) or the arrest of the circulation to an organ or part. GO:0007598 blood coagulation, extrinsic pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007598 A protein activation cascade that contributes to blood coagulation and consists of the self-limited process linking exposure and activation of tissue factor to the activation of clotting factor X. GO:0007597 blood coagulation, intrinsic pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007597 A protein activation cascade that contributes to blood coagulation and consists of the interactions among high molecular weight kininogen, prekallikrein, and factor XII that lead to the activation of clotting factor X. GO:0007596 blood coagulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007596 Wikipedia:Coagulation blood clotting The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers. GO:0007595 lactation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007595 Wikipedia:Lactation milk secretion The regulated release of milk from the mammary glands and the period of time that a mother lactates to feed her young. GO:0007594 puparial adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007594 puparial glue The adhesion of the puparia of Diptera to their substrate; normally effected by a 'glue' secreted by the larval salivary gland and expectorated at the time of pupariation. GO:0007593 chitin-based cuticle sclerotization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007593 chitin-based cuticle tanning|cuticle hardening The process of hardening of a chitin-based cuticle. GO:0007592 obsolete protein-based cuticle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007592 protein-based cuticle development|protein-based cuticle anabolism|protein-based cuticle synthesis|protein-based cuticle formation|protein-based cuticle biosynthetic process OBSOLETE. Synthesis and deposition of a protein-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this is found in Caenorhabditis elegans. GO:0032555 purine ribonucleotide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032555 Interacting selectively and non-covalently with a purine ribonucleotide, any compound consisting of a purine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety. GO:0032554 purine deoxyribonucleotide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032554 Interacting selectively and non-covalently with a purine deoxyribonucleotide, any compound consisting of a purine deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety. GO:0032553 ribonucleotide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032553 Interacting selectively and non-covalently with a ribonucleotide, any compound consisting of a ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety. GO:0032552 deoxyribonucleotide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032552 Interacting selectively and non-covalently with a deoxyribonucleotide, any compound consisting of a deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety. GO:0032551 pyrimidine ribonucleoside binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032551 Interacting selectively and non-covalently with a pyrimidine ribonucleoside, a compound consisting of a pyrimidine base linked to ribose. CHEBI:137257 omega-[(methylsulfanyl)alkyl]glucosinolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137257 GO:0032550 purine ribonucleoside binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032550 Interacting selectively and non-covalently with a purine ribonucleoside, a compound consisting of a purine base linked to ribose. GO:0032549 ribonucleoside binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032549 Interacting selectively and non-covalently with a ribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to ribose. GO:0032548 pyrimidine deoxyribonucleoside binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032548 Interacting selectively and non-covalently with a pyrimidine deoxyribonucleoside, a compound consisting of a pyrimidine base linked to deoxyribose. GO:0032547 purine deoxyribonucleoside binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032547 Interacting selectively and non-covalently with a purine deoxyribonucleoside, a compound consisting of a purine base linked to deoxyribose. GO:0032546 deoxyribonucleoside binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032546 Interacting selectively and non-covalently with a deoxyribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to deoxyribose. GO:0032545 CURI complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032545 A protein complex that is involved in the transcription of ribosomal genes. In Saccharomyces this complex consists of Ckb2p, Utp22p, Rrp7p and Ifh1p. CHEBI:137269 (5Z,8Z,11Z,17Z)-14,15-epoxyicosatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137269 GO:0032544 plastid translation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032544 plastid protein synthesis|plastid protein translation|plastid protein formation|plastid protein biosynthesis|plastid protein anabolism The chemical reactions and pathways resulting in the formation of a protein in a plastid. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the plastid has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code. GO:0032543 mitochondrial translation biolink:BiologicalProcess go-plus goslim_yeast|goslim_drosophila http://purl.obolibrary.org/obo/GO_0032543 mitochondrial protein anabolism|mitochondrial protein synthesis|mitochondrial protein formation|mitochondrial protein translation|mitochondrial protein biosynthesis The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code. GO:0032542 sulfiredoxin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032542 EC:1.8.98.2|RHEA:17545|MetaCyc:1.8.98.2-RXN sulphiredoxin activity|peroxiredoxin-(S-hydroxy-S-oxocysteine):thiol oxidoreductase [ATP-hydrolysing; peroxiredoxin-(S-hydroxycysteine)-forming]|Srx1|peroxiredoxin-(S-hydroxy-S-oxocysteine) reductase activity Catalysis of the reaction: peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 R-SH = peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + R-S-S-R. GO:0032541 cortical endoplasmic reticulum biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032541 peripheral ER|peripheral endoplasmic reticulum|ER-PM peripheral junction|cortical ER A cortical network of highly dynamic tubules that are juxtaposed to the plasma membrane and undergo ring closure and tubule-branching movements. GO:0032540 positive regulation of host-seeking behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032540 up regulation of host-seeking behavior|activation of host-seeking behavior|stimulation of host-seeking behavior|up-regulation of host-seeking behavior|upregulation of host-seeking behavior|positive regulation of host-seeking behaviour Any process that activates or increases the frequency, rate or extent of any behavior associated with finding a host organism. CHEBI:137267 (5Z,8Z,14Z,17Z)-11,12-epoxyicosatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137267 CHEBI:137265 (E)-1-(glutathion-S-yl)-2-(indol-3-yl)acetohydroximate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137265 GO:0032539 negative regulation of host-seeking behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032539 inhibition of host-seeking behavior|negative regulation of host-seeking behaviour|down regulation of host-seeking behavior|downregulation of host-seeking behavior|down-regulation of host-seeking behavior Any process that stops, prevents, or reduces the frequency, rate or extent of any behavior associated with finding a host organism. GO:0032538 regulation of host-seeking behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032538 regulation of host-seeking behaviour Any process that modulates the frequency, rate or extent of any behavior associated with finding a host organism. GO:0032537 host-seeking behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032537 host-seeking behaviour The specific behavior of an organism that are associated with finding a host organism; may include behavioral responses to light, temperature, or chemical emanations from the prospective host. GO:0032536 regulation of cell projection size biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032536 A process that modulates the size of a cell projection. GO:0007579 obsolete senescence factor accumulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007579 senescence factor accumulation OBSOLETE. (Was not defined before being made obsolete). GO:0032535 regulation of cellular component size biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032535 A process that modulates the size of a cellular component. GO:0032534 regulation of microvillus assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032534 regulation of microvillus biogenesis A process that modulates the formation of a microvillus. GO:0007578 obsolete aging dependent sterility (sensu Saccharomyces) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007578 aging dependent sterility (sensu Saccharomyces) OBSOLETE. A haploid's inability to mate due to the loss of silencing at the mating-type loci, resulting in expression of both of the normally silent mating-type cassettes. GO:0007577 obsolete autophagic death (sensu Saccharomyces) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007577 autophagic death (sensu Saccharomyces) OBSOLETE. This process is a type of programmed cell death pathway similar to apoptosis and necrosis observed in multicellular organisms. It is characterized by cellular enlargement (necrosis) and presence of many autophagic bodies along with degradation of cellular components (nucleus, Golgi, ER), protein, DNA and RNA. GO:0007576 nucleolar fragmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007576 nucleolar size increase The cell aging process that results in the nucleolus breaking down into fragments. GO:0007575 obsolete nucleolar size increase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007575 nucleolar size increase OBSOLETE. The process of nucleolar expansion. GO:0007574 obsolete cell aging (sensu Saccharomyces) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007574 cell aging (sensu Saccharomyces) OBSOLETE. Process associated with continued cell division (budding) by the mother cell. Age is often measured by counting the number of bud scars on the cell. GO:0007573 obsolete age dependent increased protein content biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007573 age dependent increased protein content OBSOLETE. (Was not defined before being made obsolete). GO:0007572 obsolete age dependent decreased translational activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007572 age dependent decreased translational activity OBSOLETE. (Was not defined before being made obsolete). GO:0007571 age-dependent general metabolic decline biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007571 age-dependent yeast cell size increase|age-dependent increased protein content|nucleolar size increase|age-dependent decreased translational activity A developmental process that arises as the cell progresses toward the end of its lifespan and cause changes cellular metabolism, resulting in a decline in cell function; for example, one aspect of general metabolic decline is a decrease in the efficiency of protein synthesis. GO:0007570 obsolete age dependent accumulation of genetic damage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007570 age dependent accumulation of genetic damage OBSOLETE. (Was not defined before being made obsolete). GO:0007580 extrachromosomal circular DNA accumulation involved in cell aging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007580 extrachromosomal circular DNA accumulation during cell ageing|extrachromosomal circular DNA accumulation during cell aging Increase in abundance, as cells age, of circular DNA molecules that originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats, and replicated independently of chromosomal replication. CHEBI:162247 2-cis,6-trans-farnesyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_162247 GO:0032533 regulation of follicle cell microvillus length biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032533 A process that modulates the length of a microvillus on a follicle cell. GO:0032532 regulation of microvillus length biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032532 A process that modulates the length of a microvillus. NCBITaxon:2605435 Evosea organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_2605435 GO:0032531 regulation of follicle cell microvillus organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032531 regulation of follicle cell microvillus organization and biogenesis|regulation of follicle cell microvillus organisation Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell. GO:0032530 regulation of microvillus organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032530 regulation of microvillus organisation|regulation of microvillus organization and biogenesis Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus. NCBITaxon:8287 Sarcopterygii organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_8287 GO:0032529 follicle cell microvillus organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032529 follicle cell microvillus organisation|follicle cell microvillus organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell. A microvillus is a thin cylindrical membrane-covered projection on the surface of an animal cell containing a core bundle of actin filaments. GO:0032528 microvillus organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032528 microvillus organization and biogenesis|microvillus organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell. GO:0032527 protein exit from endoplasmic reticulum biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032527 protein export from ER|protein export from endoplasmic reticulum|protein exit from ER The directed movement of proteins from the endoplasmic reticulum. GO:0032526 response to retinoic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032526 response to vitamin A acid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus. GO:0032525 somite rostral/caudal axis specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032525 somite rostrocaudal axis specification|somite rostrocaudal polarity The establishment, maintenance and elaboration of the rostro-caudal axis of a somite, prior to the morphological formation of a somite boundary. GO:0032524 obsolete nutrient export biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032524 nutrient export OBSOLETE. The directed movement of nutrients out of a cell or organelle. GO:0032523 silicon efflux transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032523 silicon efflux transporter activity Enables the transfer of silicon from the inside of the cell to the outside of the cell across a membrane. GO:0007589 body fluid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007589 The controlled release of a fluid by a cell or tissue in an animal. GO:0007588 excretion biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0007588 Wikipedia:Excretion The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds. GO:0007587 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007587 GO:0007586 digestion biolink:BiologicalProcess go-plus goslim_pir|goslim_chembl http://purl.obolibrary.org/obo/GO_0007586 Wikipedia:Digestion The whole of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. GO:0007585 respiratory gaseous exchange by respiratory system biolink:BiologicalProcess go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0007585 breathing|respiration The process of gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms. GO:0007584 response to nutrient biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007584 response to nutrients|nutritional response pathway Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus. GO:0007583 obsolete killer activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007583 killer activity OBSOLETE. (Was not defined before being made obsolete). GO:0007582 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007582 GO:0007581 obsolete age-dependent yeast cell size increase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007581 age-dependent yeast cell size increase OBSOLETE. (Was not defined before being made obsolete). GO:0007591 molting cycle, chitin-based cuticle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007591 chitin-based cuticle molting cycle The periodic shedding of part or all of a chitin-based cuticle, which is then replaced by a new cuticle. An example of this is found in Drosophila melanogaster. GO:0007590 obsolete fat body metabolic process (sensu Insecta) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007590 fat body metabolic process (sensu Insecta) OBSOLETE. The chemical reactions and pathways involving the fat body. A fat body is a fat-containing cellular structure which serves as an energy reserve. As in, but not restricted to, the true insects (Insecta, ncbi_taxonomy_id:50557). PR:000006267 dystroglycan biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000006267 dystrophin-associated glycoprotein 1|Dag-1|DAG1 A protein that is a translation product of the human DAG1 gene or a 1:1 ortholog thereof. GO:0032522 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032522 GO:0032521 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032521 GO:0032520 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032520 GO:0032519 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032519 GO:0032518 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032518 GO:0032517 SOD1-calcineurin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032517 A protein complex formed by the association of superoxide dismutase 1 (SOD1) with calcineurin; complex formation is implicated in activation of calcineurin by SOD1. GO:0032516 positive regulation of phosphoprotein phosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032516 activation of protein phosphatase type 2B activity|calcineurin activation|upregulation of phosphoprotein phosphatase activity|up-regulation of protein phosphatase 2 activity|positive regulation of protein phosphatase type 2A activity|stimulation of protein phosphatase 2 activity|positive regulation of protein phosphatase type 2B activity|up regulation of protein phosphatase type 2A activity|up regulation of protein phosphatase type 2B activity|activation of calcineurin activity|activation of protein phosphatase 3 activity|up regulation of phosphoprotein phosphatase activity|positive regulation of calcineurin activity|activation of phosphoprotein phosphatase activity|positive regulation of protein phosphatase 2 activity|positive regulation of protein phosphatase 3 activity|up regulation of protein phosphatase 2 activity|up regulation of calcineurin activity|up regulation of protein phosphatase 3 activity|stimulation of phosphoprotein phosphatase activity|upregulation of protein phosphatase type 2A activity|upregulation of protein phosphatase type 2B activity|upregulation of protein phosphatase 2 activity|up-regulation of phosphoprotein phosphatase activity|up-regulation of protein phosphatase type 2A activity|up-regulation of protein phosphatase type 2B activity|stimulation of protein phosphatase type 2A activity|stimulation of protein phosphatase type 2B activity|activation of protein phosphatase type 2A activity Any process that activates or increases the activity of a phosphoprotein phosphatase. GO:0032515 negative regulation of phosphoprotein phosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032515 down-regulation of protein phosphatase type 2A activity|negative regulation of protein phosphatase type 2A activity|negative regulation of protein phosphatase type 2B activity|down-regulation of protein phosphatase type 2B activity|down regulation of phosphoprotein phosphatase activity|downregulation of phosphoprotein phosphatase activity|negative regulation of protein phosphatase 2 activity|downregulation of protein phosphatase type 2A activity|negative regulation of calcineurin activity|downregulation of protein phosphatase type 2B activity|down regulation of protein phosphatase type 2A activity|down regulation of protein phosphatase type 2B activity|down-regulation of phosphoprotein phosphatase activity|downregulation of protein phosphatase 2 activity|downregulation of protein phosphatase 3 activity|downregulation of calcineurin activity|inhibition of protein phosphatase type 2A activity|regulation of protein phosphatase 3 activity|inhibition of protein phosphatase type 2B activity|down regulation of protein phosphatase 2 activity|down regulation of protein phosphatase 3 activity|down regulation of calcineurin activity|inhibition of phosphoprotein phosphatase activity|inhibition of protein phosphatase 2 activity|inhibition of protein phosphatase 3 activity|inhibition of calcineurin activity Any process that stops or reduces the activity of a phosphoprotein phosphatase. GO:0007559 obsolete histolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007559 Wikipedia:Histolysis OBSOLETE. The breakdown of tissues; usually, if not always, accompanied by cell death, followed by the complete dissolution of dead tissue. GO:0007558 regulation of juvenile hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007558 Any process that modulates the frequency, rate or extent of juvenile hormone secretion. GO:0032514 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032514 GO:0007557 regulation of juvenile hormone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007557 regulation of juvenile hormone anabolism|regulation of juvenile hormone synthesis|regulation of juvenile hormone formation|regulation of juvenile hormone biosynthesis Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone. GO:0032513 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032513 GO:0032512 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032512 GO:0007556 regulation of juvenile hormone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007556 regulation of juvenile hormone metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone. GO:0007555 regulation of ecdysteroid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007555 Any process that modulates the frequency, rate or extent of the regulated release of ecdysteroid from a cell. GO:0007554 regulation of ecdysteroid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007554 regulation of ecdysteroid biosynthesis|regulation of ecdysteroid anabolism|regulation of ecdysteroid synthesis|regulation of ecdysteroid formation Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ecdysteroids. GO:0007553 regulation of ecdysteroid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007553 regulation of ecdysteroid metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development, including the metamorphosis of immature forms and the development of the reproductive system and the maturation of oocytes in adult females. GO:0007552 metamorphosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007552 Wikipedia:Metamorphosis A biological process in which an animal physically develops after birth or hatching, involving a conspicuous and relatively abrupt change in the animal's form or structure. Examples include the change from tadpole to frog, and the change from larva to adult. An example of this is found in Drosophila melanogaster. GO:0007551 obsolete maintenance of dosage compensation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007551 maintenance of dosage compensation OBSOLETE. (Was not defined before being made obsolete). GO:0007550 obsolete establishment of dosage compensation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007550 establishment of dosage compensation OBSOLETE. (Was not defined before being made obsolete). GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032511 endosome to vacuole transport via MVB sorting pathway The directed movement of substances from endosomes to vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the vacuole. GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032510 endosome to lysosome transport via MVB sorting pathway The directed movement of substances from endosomes to lysosomes by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the lysosome. CHEBI:137211 (E)-2-(indol-3-yl)-1-thioacetohydroximic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137211 GO:0032508 DNA duplex unwinding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032508 duplex DNA melting|DNA unwinding The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating a region of unpaired single strands. GO:0032507 maintenance of protein location in cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032507 maintenance of protein localization in cell Any process in which a protein is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere. GO:0032506 cytokinetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032506 A cellular process that is involved in cytokinesis (the division of the cytoplasm of a cell and its separation into two daughter cells). GO:0032505 reproduction of a single-celled organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032505 The biological process in which new individuals are produced by one or two single-celled organisms. The new individuals inherit some proportion of their genetic material from the parent or parents. GO:0032504 multicellular organism reproduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032504 The biological process in which new individuals are produced by one or two multicellular organisms. The new individuals inherit some proportion of their genetic material from the parent or parents. GO:0007569 cell aging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007569 cell ageing An aging process that has as participant a cell after a cell has stopped dividing. Cell aging may occur when a cell has temporarily stopped dividing through cell cycle arrest (GO:0007050) or when a cell has permanently stopped dividing, in which case it is undergoing cellular senescence (GO:0090398). May precede cell death (GO:0008219) and succeed cell maturation (GO:0048469). GO:0032503 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032503 GO:0007568 aging biolink:BiologicalProcess go-plus goslim_generic|goslim_chembl http://purl.obolibrary.org/obo/GO_0007568 Wikipedia:Aging ageing A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700). GO:0032502 developmental process biolink:BiologicalProcess go-plus goslim_flybase_ribbon|goslim_agr|goslim_pir|goslim_aspergillus http://purl.obolibrary.org/obo/GO_0032502 single-organism developmental process|development A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition. GO:0032501 multicellular organismal process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0032501 single-multicellular organism process|organismal physiological process Any biological process, occurring at the level of a multicellular organism, pertinent to its function. GO:0007567 parturition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007567 giving birth|egg laying The reproductive process in which the parent is separated from its offspring either by giving birth to live young or by laying eggs. GO:0007566 embryo implantation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007566 blastocyst implantation Attachment of the blastocyst to the uterine lining. GO:0007565 female pregnancy biolink:BiologicalProcess go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0007565 Wikipedia:Gestation carrying of young|gestation The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth. GO:0007564 regulation of chitin-based cuticle tanning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007564 regulation of cuticle tanning|regulation of cuticle hardening Any process that modulates the frequency, rate or extent of chitin-based cuticular tanning. GO:0007563 regulation of eclosion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007563 Any process that modulates the frequency, rate or extent of the emergence of an insect from a pupa-case or of a larva from an egg. GO:0007562 eclosion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007562 Wikipedia:Pupa#Emergence The emergence of an adult insect from a pupa case. GO:0007561 imaginal disc eversion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007561 The eversion (turning inside out) of imaginal discs from their peripodial sacs, resulting in movement of the epithelium to the outside of the larval epidermis. GO:0007560 imaginal disc morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007560 imaginal disc metamorphosis The process in which the anatomical structures derived from an imaginal disc are generated and organized. The imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult appendages (legs, antennae, wings, etc.) during metamorphosis from larval to adult form. GO:0032509 endosome transport via multivesicular body sorting pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032509 endosome transport via MVB sorting pathway The directed movement of substances from endosomes to lysosomes or vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the target compartment. GO:0032500 muramyl dipeptide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032500 Interacting selectively and non-covalently, in a non-covalent manner, with muramyl dipeptide; muramyl dipeptide is derived from peptidoglycan. OBO:GOCHE_24432 substance with biological role role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_24432 GO:0007539 primary sex determination, soma biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007539 The transmission of information about sexual status from the initial, general, determination to signals specific to the soma. GO:0007538 primary sex determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007538 The sex determination process that results in the initial specification of sexual status of an individual organism. GO:0007537 inactivation of recombination (HML) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007537 The inactivation of recombination at sequences around a mating type donor locus, with the consequence that the other donor is the only one available for mating type switching; exemplified by the HML locus and surrounding sequences on Chromosome III in Saccharomyces cerevisiae. GO:0007536 activation of recombination (HML) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007536 The activation of recombination at a mating type locus, such that it is used in preference to the other donor locus for mating type switching; exemplified by the HML locus and surrounding sequences on Chromosome III in Saccharomyces cerevisiae. GO:0007535 donor selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007535 donor preference The process that determines which donor locus a cell uses, in preference to another, in mating type switching. GO:0007534 gene conversion at mating-type locus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007534 gene conversion at mating-type locus, termination of copy-synthesis|gene conversion at mating-type locus, DNA double-strand break formation|heteroduplex formation involved in gene conversion at mating-type locus|gene conversion at mating-type locus, DNA repair synthesis|strand invasion involved in gene conversion at mating-type locus|gene conversion at mating-type locus, DNA double-strand break processing The conversion of the mating-type locus from one allele to another resulting from the recombinational repair of a site-specific double-strand break at the mating-type locus with information from a silent donor sequence. There is no reciprocal exchange of information because the mating-type locus copies information from the donor sequence and the donor sequence remains unchanged. GO:0007533 mating type switching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007533 mating type switching and recombination The conversion of a single-cell organism from one mating type to another by the precise replacement of a DNA sequence at the expressed mating type locus with a copy of a sequence from a donor locus. GO:0007532 regulation of mating-type specific transcription, DNA-templated biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007532 regulation of mating-type specific transcription, DNA-dependent|mating-type specific transcriptional control Any mating-type specific process that modulates the frequency, rate or extent of cellular DNA-templated transcription. GO:0007531 mating type determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007531 Any process that establishes and transmits the specification of mating type upon an individual. Mating types are the equivalent in microorganisms of the sexes in higher organisms. GO:0007530 sex determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007530 Wikipedia:Sex-determination_system Any process that establishes and transmits the specification of sexual status of an individual organism. GO:0007549 dosage compensation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007549 Wikipedia:Dosage_compensation Compensating for the variation in the unpaired sex chromosome:autosome chromosome ratios between sexes by activation or inactivation of genes on one or both of the sex chromosomes. GO:0007548 sex differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007548 Wikipedia:Sexual_differentiation The establishment of the sex of an organism by physical differentiation. GO:0007547 germ-line processes downstream of sex determination signal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007547 The events determining the germ-line sexual phenotype after the initial transmission of that phenotype to germ-line-specific information pathways. GO:0007546 somatic processes downstream of sex determination signal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007546 The events determining the somatic sexual phenotype after the initial transmission of that phenotype to soma-specific information pathways. GO:0007545 processes downstream of sex determination signal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007545 The sex determination processes that take place after the initial transmission of the sexual phenotype to specific information pathways. GO:0007544 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007544 GO:0007543 sex determination, somatic-gonadal interaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007543 sex determination, somatic/gonadal interaction The process that mediates the interactions between somatic cells and gonadal cells that ultimately results in the specification of sexual status of the organism. GO:0007542 primary sex determination, germ-line biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007542 The transmission of information about sexual status, from the initial general determination, to signals specific to the germ-line. GO:0007541 sex determination, primary response to X:A ratio biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007541 The developmental process in which an organism interprets its X to autosomal chromosomal complement. CHEBI:45599 dodecyl hydrogen sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_45599 GO:0007540 sex determination, establishment of X:A ratio biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007540 The developmental process in which an organism senses the number of X chromosomes and autosomes in its genomic complement and responds to it. CHEBI:137207 N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAcl-(1->4)-[alpha-L-Fuc-(1->6)]-beta-D-GlcNAc}-Asn residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137207 UBERON_CORE:anteriorly_connected_to anteriorly connected to biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/uberon/core#anteriorly_connected_to anteriorly_connected_to x anteriorly_connected_to y iff the anterior part of x is connected to y. i.e. x connected_to y and x posterior_to y. UBERON:6007242 embryonic/larval head sensillum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_6007242 larval head sensillum Any sensillum (UBERON:6007152) that is part of some larval head (UBERON:6001730). UBERON:6007240 embryonic/larval sensillum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_6007240 larval sensillum Any sensillum (UBERON:6007152) that is part of some larva (UBERON:6001727). CHEBI:69579 hederagenin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_69579 GO:0032591 dendritic spine membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032591 The portion of the plasma membrane surrounding a dendritic spine. GO:0032590 dendrite membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032590 The portion of the plasma membrane surrounding a dendrite. NCBITaxon:32525 Theria organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_32525 Theria GO:0032599 protein transport out of membrane raft biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032599 receptor translocation out of membrane raft|receptor transport out of membrane raft|protein translocation out of membrane raft|protein transport out of lipid raft The directed movement of a protein out of a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. CHEBI:137297 mycobilin b biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137297 GO:0032598 B cell receptor transport into immunological synapse biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032598 BCR translocation into immunological synapse|B cell receptor translocation into immunological synapse|BCR transport into immunological synapse The directed movement of a B cell receptor into an immunological synapse. GO:0032597 B cell receptor transport into membrane raft biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032597 BCR translocation into membrane raft|B cell receptor transport into lipid raft|B cell receptor translocation into membrane raft|BCR transport into membrane raft The directed movement of a B cell receptor into a membrane raft. NCBITaxon:32524 Amniota organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_32524 amniotes GO:0032596 protein transport into membrane raft biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032596 protein transport into lipid raft|receptor translocation into membrane raft|protein translocation into membrane raft|receptor transport into membrane raft The directed movement of a protein into a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. NCBITaxon:32523 Tetrapoda organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_32523 tetrapods GO:0032595 B cell receptor transport within lipid bilayer biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032595 BCR translocation within membrane|BCR transport within lipid bilayer|B cell receptor translocation within membrane The directed movement of a B cell receptor within a lipid bilayer. GO:0032594 protein transport within lipid bilayer biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032594 protein translocation within membrane|receptor translocation within membrane|receptor transport within lipid bilayer The directed movement of a protein from one location to another within a lipid bilayer. GO:0032593 insulin-responsive compartment biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032593 GLUT4 storage compartment|IRC|GSC A small membrane-bounded vesicle that releases its contents by exocytosis in response to insulin stimulation; the contents are enriched in GLUT4, IRAP and VAMP2. CHEBI:137299 biliverdin delta biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137299 GO:0032592 integral component of mitochondrial membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032592 integral to mitochondrial membrane The component of the mitochondrial membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. CHEBI:137298 biliverdin beta biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137298 GO:0032589 neuron projection membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032589 The portion of the plasma membrane surrounding a neuron projection. GO:0032580 Golgi cisterna membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032580 Golgi stack membrane The lipid bilayer surrounding any of the thin, flattened compartments that form the central portion of the Golgi complex. GO:0032588 trans-Golgi network membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032588 Golgi trans face membrane|trans Golgi network membrane The lipid bilayer surrounding any of the compartments that make up the trans-Golgi network. GO:0032587 ruffle membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032587 membrane ruffle The portion of the plasma membrane surrounding a ruffle. GO:0032586 protein storage vacuole membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032586 The lipid bilayer surrounding a protein storage vacuole. GO:0032585 multivesicular body membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032585 MVB membrane|multivesicular endosome membrane|MVE membrane The lipid bilayer surrounding a multivesicular body. GO:0032584 growth cone membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032584 The portion of the plasma membrane surrounding a growth cone. GO:0032583 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032583 GO:0032582 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032582 GO:0032581 ER-dependent peroxisome organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032581 ER-dependent peroxisome biogenesis|ER-dependent peroxisome organisation|endoplasmic reticulum-dependent peroxisome organization A process of peroxisome organization in which assembly or arrangement of constituent parts takes place in the endoplasmic reticulum. CHEBI:137281 (Z)-1-(glutathione-S-yl)-2-phenylacetohydroximate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137281 GO:0032579 apical lamina of hyaline layer biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032579 A fibrous network that is part of the hyalin layer extracellular matrix. The apical lamina is thought to be principally composed of the glycoproteins fibropellins. This matrix has been found in echinoderms. GO:0032578 aleurone grain membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032578 The lipid bilayer surrounding an aleurone grain. GO:0032577 phosphatidylcholine:cardiolipin O-linoleoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032577 phosphatidylcholine:cardiolipin linoleoyltransferase Catalysis of the transfer of a linoleoyl ((9Z,12Z)-octadeca-9,12-dienoyl) group from phosphatidylcholine to an oxygen atom on a cardiolipin molecule. GO:0032576 O-linoleoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032576 Catalysis of the transfer of a linoleoyl ((9Z,12Z)-octadeca-9,12-dienoyl) group to an oxygen atom on the acceptor molecule. GO:0032575 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032575 GO:0032574 5'-3' RNA helicase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032574 Reactome:R-HSA-9682695|Reactome:R-HSA-9694265 5' to 3' RNA helicase activity|ATP-dependent 5'-3' RNA helicase activity|ATP-dependent 5' to 3' RNA helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix in the direction 5' to 3'. GO:0032573 response to phylloquinone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032573 response to vitamin K1 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phylloquinone (vitamin K1) stimulus. GO:0032572 response to menaquinone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032572 response to menatetrenone|response to vitamin K2 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menaquinone (vitamin K2) stimulus. GO:0032571 response to vitamin K biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032571 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin K stimulus. GO:0032570 response to progesterone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032570 response to progesterone stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus. GO:0032569 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032569 GO:0032568 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032568 GO:0032567 dGTP binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032567 Interacting selectively and non-covalently with dGTP, deoxyguanosine triphosphate. GO:0032566 dGDP binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032566 Interacting selectively and non-covalently with dGDP, deoxyguanosine diphosphate. GO:0032565 dGMP binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032565 Interacting selectively and non-covalently with dGMP, deoxyguanosine monophosphate. GO:0032564 dATP binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032564 Interacting selectively and non-covalently with dATP, deoxyadenosine triphosphate. GO:0032563 dADP binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032563 Interacting selectively and non-covalently with dADP, deoxyadenosine diphosphate. GO:0032562 dAMP binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032562 Interacting selectively and non-covalently with dAMP, deoxyadenosine monophosphate. GO:0032561 guanyl ribonucleotide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032561 Interacting selectively and non-covalently with a guanyl ribonucleotide, any compound consisting of guanosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety. GO:0032560 guanyl deoxyribonucleotide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032560 Interacting selectively and non-covalently with a guanyl deoxyribonucleotide, any compound consisting of guanosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety. CHEBI:137287 mycobilin a biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137287 GO:0140225 DNA topoisomerase III-beta-TDRD3 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140225 Top3-beta-TDRD3 complex A protein complex that has DNA topoisomerase type I and RNA topoisomerase activities. GO:0140224 SLAC complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140224 IntAct:EBI-7506670 A protein complex that regulates Arp2/3 complex-mediated actin nucleation. GO:0140227 serotonin-gated cation-selective signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140227 ComplexPortal:CPX-278|ComplexPortal:CPX-277|ComplexPortal:CPX-276|ComplexPortal:CPX-275|ComplexPortal:CPX-274|ComplexPortal:CPX-273|ComplexPortal:CPX-272|ComplexPortal:CPX-271|ComplexPortal:CPX-2175 5-HT-gated cation-selective signalling pathway|5-HT-gated cation-selective signaling pathway|5-hydroxytryptamine-gated cation-selective signaling pathway|5-hydroxytryptamine-gated cation-selective signalling pathway|serotonin-gated cation-selective signalling pathway A series of molecular signals initiated by serotonin binding to a seratonin receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription. GO:0140226 RNA topoisomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140226 Catalysis of the transient cleavage and passage of individual RNA strands or double helices through one another, resulting a topological transformation in RNA. GO:0140221 pathogen-containing vacuole membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140221 pathogen inclusion membrane|pathogen-containing compartment membrane Host-derived membrane of a pathogen-containing vacuole. GO:0140220 pathogen-containing vacuole biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140220 pathogen-containing compartment|pathogen inclusion A membrane-bound intracellular compartment that is formed upon internalization of a pathogen into a host cell, and in which the pathogen resides. CHEBI:45506 alpha-D-ribose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_45506 GO:0140223 general transcription initiation factor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140223 GTF activity|basal transcription factor activity|general transcription factor activity A molecular function required for core promoter activity that mediates the assembly of the RNA polymerase holoenzyme at promoter DNA to form the pre-initiation complex (PIC). General transcription factors (GTFs) bind to and open promoter DNA, initiate RNA synthesis and stimulate the escape of the polymerase from the promoter. Not all subunits of the general transcription factor are necessarily present at all promoters to initiate transcription. GTFs act at each promoter, although the exact subunit composition at individual promoters may vary. GO:0140222 pathogen-containing vacuole lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140222 pathogen-containing compartment lumen|pathogen inclusion lumen|lumen of a pathogen-containing vacuole|pathogen-containing vacuolar lumen The enclosed volume within the sealed membrane of a pathogen-containing vacuole. NCBITaxon:32561 Sauria organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_32561 Diapsida|diapsids CHEBI:21545 N-acetyl-L-amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21545 GO:0140214 positive regulation of long-chain fatty acid import into cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140214 Any process that activates or increases the frequency, rate or extent of long-chain fatty acid import into a cell. GO:0140213 negative regulation of long-chain fatty acid import into cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140213 Any process that stops, prevents or reduces the frequency, rate or extent of long-chain fatty acid import into a cell. GO:0140216 negative regulation of D-aspartate import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140216 Any process that stops, prevents or reduces the frequency, rate or extent of the directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol. GO:0140215 regulation of D-aspartate import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140215 Any process that modulates the frequency, rate or extent of the directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol. GO:0140217 positive regulation of D-aspartate import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140217 Any process that activates or increases the frequency, rate or extent of the directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol. GO:0140210 protein transport along microtubule to kinetochore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140210 Any process in which a protein is transported to the kinetochore along a microtubule. GO:0140212 regulation of long-chain fatty acid import into cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140212 Any process that modulates the frequency, rate or extent of long-chain fatty acid import into a cell. GO:0140211 folic acid:proton symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140211 TC:2.A.1.50.1 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: folic acid(out) + H+(out) = folic acid(in) + H+(in). The main folic acid symporter is the Proton-Coupled Folate Transporter (PCFT/SLC46A1), which has similar affinity for transport of reduced folates (5-methyl THF, 5-formyl THF) and folic acid. CHEBI:21547 N-acetyl-L-aspartic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21547 CHEBI:21549 N-acetyl-L-glutamate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21549 GO:0140247 protein catabolic process at presynapse biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0140247 The chemical reactions and pathways resulting in the breakdown of a protein at a presynapse. GO:0140246 protein catabolic process at synapse biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0140246 The chemical reactions and pathways resulting in the breakdown of a protein at a synapse. GO:0140249 protein catabolic process at postsynapse biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0140249 The chemical reactions and pathways resulting in the breakdown of a protein at a postsynapse. GO:0140241 translation at synapse biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0140241 Translation that occurs at the synapse. GO:0140240 perforant pathway to dendrate granule cell synapse biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0140240 perforant pathway to DG granule cell synapse A neuron to neuron synapse of a pyramidal neuron in the entorhinal cortex onto a granule cell in the dentate gyrus of the hippocampus. GO:0140243 regulation of translation at synapse biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0140243 Any process that regulates translation occurring at the synapse. GO:0140242 translation at postsynapse biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0140242 Translation that occurs at the postsynapse. GO:0140245 regulation of translation at postsynapse biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0140245 Any process that regulates translation occurring at the postsynapse. GO:0140244 regulation of translation at presynapse biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0140244 Any process that regulates translation occurring at the presynapse. CHEBI:21519 N-acetyl-D-glucosamine 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21519 UBERON:0016570 lamina of gray matter of spinal cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016570 rexed lamina GO:0140236 translation at presynapse biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0140236 Translation that occurs at the presynapse. GO:0140235 RNA polyadenylation at postsynapse biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0140235 A polyadenylation event (the enzymatic addition of a sequence of adenylyl residues at the 3' end of an RNA molecule) that takes place at a postsynapse. GO:0140238 presynaptic endocytosis biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0140238 A vesicle-mediated transport process in which the presynapse take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle. GO:0140237 translation at presynapse, modulating chemical synaptic transmission biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0140237 Translation that occurs at the presynapse, and that modulates chemical synaptic transmission. GO:0140239 postsynaptic endocytosis biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0140239 A vesicle-mediated transport process in which the postsynapse take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle. GO:0140232 intracellular cAMP-activated cation channel activity involved in regulation of presynaptic membrane potential biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0140232 intracellular cAMP activated cation channel activity involved in regulation of presynaptic membrane potential Enables the transmembrane transfer of a cation by a channel that opens when intracellular cAMP has been bound by the channel complex or one of its constituent parts, to regulate the presynaptic membrane potential. GO:0140231 anterograde axonal transport of neurotransmitter receptor complex biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0140231 The directed movement of a neurotransmitter receptor complex along microtubules from the cell body toward the cell periphery in nerve cell axons. GO:0140233 intracellular cAMP-activated cation channel activity involved in regulation of postsynaptic membrane potential biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0140233 intracellular cAMP activated cation channel activity involved in regulation of postsynaptic membrane potential Enables the transmembrane transfer of a cation by a channel that opens when intracellular cAMP has been bound by the channel complex or one of its constituent parts, to regulate the postsynaptic membrane potential. CHEBI:21524 N-acetyl-D-glucosaminyl groups biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21524 CHEBI:21501 N-acetyl-D-amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21501 CHEBI:21500 N-acetyl-9-O-acetylneuraminic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21500 CHEBI:21507 N-acetyl-D-galactosaminyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21507 CHEBI:21509 N-acetyl-beta-D-galactosaminyl-(1->4)-alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-N-acylsphingosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21509 GO:0140203 spermidine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140203 The directed movement of spermidine from outside of a cell, across the plasma membrane and into the cytosol. GO:0140202 polyamine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140202 The directed movement of a polyamine from outside of a cell, across the plasma membrane and into the cytosol. GO:0140205 oligopeptide import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140205 The directed movement of an oligopeptide from outside of a cell, across the plasma membrane and into the cytosol. GO:0140204 pyridoxal import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140204 The directed movement of pyridoxal from outside of a cell, across the plasma membrane and into the cytosol. GO:0140207 tripeptide import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140207 The directed movement of a tripeptide from outside of a cell, across the plasma membrane and into the cytosol. GO:0140206 dipeptide import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140206 The directed movement of a dipeptide from outside of a cell, across the plasma membrane and into the cytosol. GO:0140209 zinc ion import into endoplasmic reticulum biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140209 zinc(2+) import into endoplasmic reticulum|zinc(2+) import across endoplasmic reticulum|zinc ion import across endoplasmic reticulum|zinc ion import into ER The directed import of zinc(2+) from the cytosol, across the endoplasmic reticulum membrane, into the endoplasmic reticulum. GO:0140208 apoptotic process in response to mitochondrial fragmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140208 apoptosis in response to mitochondrial fragmentation Any apoptotic process that occurs as a result of mitochondrial fragmentation. UBERON:6007149 segment of antenna biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_6007149 Any appendage segment that is part of some antenna. GO:0140201 urea import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140201 The directed movement of urea from outside of a cell, across the plasma membrane and into the cytosol. GO:0140200 adenylate cyclase-activating adrenergic receptor signaling pathway involved in regulation of heart rate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140200 An adrenergic receptor signaling pathway that modulates the frequency or rate of heart contraction. UBERON:6007150 segment of leg biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_6007150 Any appendage segment (UBERON:6007018) that is part of some leg (UBERON:6004640). GO:0007519 skeletal muscle tissue development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007519 myogenesis The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers. GO:0007518 myoblast fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007518 The cell fate determination process in which a cell becomes capable of differentiating autonomously into a myoblast regardless of its environment; upon determination, the cell fate cannot be reversed. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. GO:0007517 muscle organ development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007517 The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work. GO:0007516 hemocyte development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007516 arthropod blood cell development The process whose specific outcome is the progression of the hemocyte over time, from its formation to the mature structure. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. GO:0007515 obsolete lymph gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007515 lymph gland development OBSOLETE. The process whose specific outcome is the progression of the lymph gland over time, from its formation to the mature structure. The lymph gland is a small bean-shaped organ made up of a loose meshwork of reticular tissue in which are enmeshed large numbers of lymphocytes, macrophages and accessory cells. Lymph glands are located along the lymphatic system. GO:1900998 nitrobenzene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900998 nitrobenzene degradation|nitrobenzene breakdown|nitrobenzene catabolism The chemical reactions and pathways resulting in the breakdown of nitrobenzene. GO:1900997 benzene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900997 benzene synthesis|benzene biosynthesis|benzene formation|benzene anabolism The chemical reactions and pathways resulting in the formation of benzene. GO:0007514 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007514 GO:0007513 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007513 GO:1900999 nitrobenzene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900999 nitrobenzene biosynthesis|nitrobenzene anabolism|nitrobenzene synthesis|nitrobenzene formation The chemical reactions and pathways resulting in the formation of nitrobenzene. GO:0007512 adult heart development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007512 adult cardiac development The process whose specific outcome is the progression of the adult heart over time, from its formation to the mature structure. GO:1900994 (-)-secologanin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900994 (-)-secologanin formation|(-)-secologanin biosynthesis|(-)-secologanin anabolism|(-)-secologanin synthesis The chemical reactions and pathways resulting in the formation of (-)-secologanin. GO:0007511 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007511 UBERON:0016525 frontal lobe biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016525 lobus frontalis|frontal region|frontal cortex|regio frontalis|lobi frontales Frontal lobe is the anterior-most of five lobes of the cerebral hemisphere. It is bounded by the central sulcus on its posterior border and by the longitudinal cerebral fissure on its medial border. GO:1900993 (-)-secologanin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900993 (-)-secologanin catabolism|(-)-secologanin degradation|(-)-secologanin breakdown The chemical reactions and pathways resulting in the breakdown of (-)-secologanin. GO:0007510 cardioblast cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007510 The cell fate determination process in which a cell becomes capable of differentiating autonomously into a cardioblast cell regardless of its environment; upon determination, the cell fate cannot be reversed. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. GO:1900996 benzene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900996 benzene catabolism|benzene degradation|benzene breakdown The chemical reactions and pathways resulting in the breakdown of benzene. UBERON:0016527 white matter of cerebral lobe biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016527 UBERON:0016526 lobe of cerebral hemisphere biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016526 lobe of cerebral cortex|lobe parts of cerebral cortex|regional organ part of cerebral cortex|cerebral lobe|cerebral cortical segment|segment of cerebral cortex|cerebral hemisphere lobe|lobi cerebri|lobes of the brain Subdivision of telencephalon which is one of a number of subdivisions of each hemisphere separated by both real landmarks (sulci and fissures) and arbitrary boundaries[FMA,modified]. GO:1900995 ubiquinone-6 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1900995 Interacting selectively and non-covalently with ubiquinone-6. Ubiquinone-6 is a ubiquinone compound having a (2E,6E,10E,14E,18E)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-yl substituent at position 2. GO:1900990 scopolamine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900990 scopolamine degradation|scopolamine catabolism|scopolamine breakdown The chemical reactions and pathways resulting in the breakdown of scopolamine. UBERON:0016520 epithelium of female urethra biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016520 urethral epithelium of female|female urethral epithelium A epithelium that is part of a female urethra. GO:1900992 (-)-secologanin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900992 (-)-secologanin metabolism The chemical reactions and pathways involving (-)-secologanin. GO:1900991 scopolamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900991 scopolamine anabolism|scopolamine synthesis|scopolamine formation|scopolamine biosynthesis The chemical reactions and pathways resulting in the formation of scopolamine. UBERON:0016522 cavity of right atrium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016522 right atrial cavity luminal space of the right atrium of the heart. CHEBI:3543 cephamycin C biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_3543 GO:0007529 establishment of synaptic specificity at neuromuscular junction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007529 The biological process in which a synapse between a motor neuron and a muscle is initially formed. CHEBI:45571 heptanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_45571 GO:0007528 neuromuscular junction development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007528 neuromuscular junction stability|NMJ stability|neuromuscular junction organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction. GO:0007527 adult somatic muscle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007527 The process whose specific outcome is the progression of the adult somatic muscle over time, from its formation to the mature structure. GO:0007526 larval somatic muscle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007526 The process whose specific outcome is the progression of the larval somatic muscle over time, from its formation to the mature structure. GO:0007525 somatic muscle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007525 The process whose specific outcome is the progression of the somatic muscle over time, from its formation to the mature structure. Somatic muscles are striated muscle structures that connect to the exoskeleton or cuticle. GO:0007524 adult visceral muscle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007524 The process whose specific outcome is the progression of the adult visceral muscle over time, from its formation to the mature structure. GO:0007523 larval visceral muscle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007523 The process whose specific outcome is the progression of the larval visceral muscle over time, from its formation to the mature structure. GO:0007522 visceral muscle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007522 The process whose specific outcome is the progression of the visceral muscle over time, from its formation to the mature structure. UBERON:0016514 cavity of left ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016514 left ventricular cavity luminal space of the left ventricle of the heart. UBERON:0016513 cavity of left atrium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016513 left atrium lumen|left atrial cavity luminal space of the left atrium of the heart. GO:0007521 muscle cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007521 The cell fate determination process in which a cell becomes capable of differentiating autonomously into a muscle cell regardless of its environment; upon determination, the cell fate cannot be reversed. GO:0007520 myoblast fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007520 A process in which non-proliferating myoblasts fuse to existing fibers or to myotubes to form new fibers. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. UBERON:0016510 epithelium of male urethra biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016510 male urethral epithelium|urethral epithelium of male A epithelium that is part of a male urethra. UBERON:0016512 lumen of duodenum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016512 duodenal lumen|doudenal lumen A anatomical space that is part of a duodenum. GO:0140294 NAD DNA ADP-ribosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140294 Catalysis of the transfer of the ADP-ribose group of NAD+ to a residue in double-stranded DNA. CHEBI:137305 (9Z,12Z)-11-hydroxyoctadecadienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137305 GO:0140293 ADP-ribosylglutamate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140293 Catalysis of the reaction: (ADP-D-ribosyl)-L-glutamyl-[protein] + H2O = L-glutamyl-[protein] + ADP-ribose. GO:0140296 general transcription initiation factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140296 Interacting selectively and non-covalently with a general transcription initiation factor, a protein that contributes to transcription start site selection and transcription initiation. GO:0140295 pathogen-derived receptor ligand activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140295 innate receptor ligand activity The activity of a pathogen-derived entity that interacts with a host receptor to activate effector-triggered immunity. CHEBI:137302 7,7-dihydroxybacteriochlorophyllide c biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137302 GO:0140298 endocytic iron import into cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140298 iron import into cell by endocytosis Uptake of iron into a cell via binding to an extracellular receptor, which is internalized by endocytosis. GO:0140297 DNA-binding transcription factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140297 Interacting selectively and non-covalently with a DNA-binding transcription factor, a protein that interacts with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. UBERON:0016509 cavity of right ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016509 right ventricular cavity|right ventricle lumen Luminal space of the right ventricle of the heart. GO:0140299 small molecule sensor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140299 small molecular sensor activity Binding to a small molecule and eliciting a change in the protein's activity in response to the intracellular level of that small molecule. GO:0140290 peptidyl-serine ADP-deribosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140290 The removal of ADP-ribose from ADP-ribosylserine. CHEBI:137300 bacteriochlorophyllide e biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137300 GO:0140292 ADP-ribosylserine hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140292 Catalysis of the reaction: (ADP-D-ribosyl)-L-seryl-[protein] + H2O = L-seryl-[protein] + ADP-ribose. GO:0140291 peptidyl-glutamate ADP-deribosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140291 The removal of ADP-ribose from ADP-ribosylglutamate. CHEBI:3528 cellotriose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_3528 CHEBI:45564 5-hydroxypentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_45564 CHEBI:3523 cellodextrin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_3523 GO:0007508 larval heart development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007508 The process whose specific outcome is the progression of the larval heart over time, from its formation to the mature structure. In Drosophila the larval heart (dorsal vessel) is a continuous tube of mesodormal cells that runs beneath the dorsal midline of the epidermis, divided into an anterior aorta and a posterior heart proper. GO:0007507 heart development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007507 Wikipedia:Heart_development cardiac development|dorsal vessel development The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. GO:0007506 gonadal mesoderm development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007506 The process whose specific outcome is the progression of the gonadal mesoderm over time, from its formation to the mature structure. The gonadal mesoderm is the middle layer of the three primary germ layers of the embryo which will go on to form the gonads of the organism. GO:0007505 adult fat body development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007505 The process whose specific outcome is the progression of the adult fat body over time, from its formation to the mature structure. Larval fat body cells that remain at eclosion degenerate in the first 2 to 4 days of adult life, leaving behind the smaller cells of the adult fat body. GO:0007504 larval fat body development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007504 The process whose specific outcome is the progression of the larval fat body over time, from its formation to the mature structure. The larval fat body consists of a bilaterally symmetrical monolayer of cells lying between the gut and the muscles of the body wall. As in other tissues of the larva, the cells of the fat body complete their divisions in the embryo and increase in size and ploidy during larval life. GO:0007503 fat body development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007503 The process whose specific outcome is the progression of the fat body over time, from its formation to the mature structure. A fat body is an insect gland dorsal to the insect gut, with a function analogous to that of the vertebrate liver. It is a storage organ for fats, glycogen and protein and is a major site of intermediary metabolism. GO:0007502 digestive tract mesoderm development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007502 The process whose specific outcome is the progression of the digestive tract mesoderm over time, from its formation to the mature structure. The digestive tract mesoderm is portion of the middle layer of the three primary germ layers of the embryo which will go on to form part of the digestive tract of the organism. GO:0007501 mesodermal cell fate specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007501 mesoderm cell fate specification The cell fate determination process in which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. GO:0007500 mesodermal cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007500 mesoderm cell fate determination The cell fate determination process in which a cell becomes capable of differentiating autonomously into a mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed. CHEBI:45557 sec-butyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_45557 GO:0007509 mesoderm migration involved in gastrulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007509 The migration of mesodermal cells during gastrulation to help establish the multilayered body plan of the organism. CHEBI:21575 N-acetyl-amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21575 UBERON:0016569 subcupular meshwork of statoconial membrane biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016569 An acellular membrane in the inner ear that is part of the statoconial membrane and consists of long branching filaments cross-bridged to one another. The filaments are continuous with those of the otolithic membrane on one side and with the surface of the epithelium on the other. GO:0140268 endoplasmic reticulum-plasma membrane contact site biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140268 ER-PM contact site|endoplasmic reticulum-plasma membrane contact junction|EPCS|ER-plasma membrane contact site A contact site between the endoplasmic reticulum membrane and the plasma membrane, structured by bridging complexes. UBERON:0016565 cerebral blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016565 A blood vessel that is part of a cerebellum. UBERON:0016567 statoconial membrane biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016567 otolith membrane|otoconial-statoconial membrane An acellular membrane in the vestibular labyrinth that is composed of the otoconial layer, gelatinous layer, and a subcupular meshwork. UBERON:0016566 pit biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016566 An roughly circular indentation in a surface. GO:0140261 BCOR complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140261 non-canonical PRC1-BCOR complex|BCOR/BCORL1 complex|PRC1.1 complex|non-canonical BCOR-PRC1.1 complex|BCL6 corepressor (BCOR) complex A protein-containing complex that monoubiquitinates histone H2A on K119, thus it facilitates the maintenance of the transcriptionally repressive state of some genes, such as BCL6. It consists of the corepressor BCOR or BCORL1, a Polycomb group (PcG) and a SCF ubiquitin ligase subcomplexes. In mammals, the core subunits of the complex include the PcG and PcG-associated proteins NSPC1, RING1, RNF2, and RYBP and the components of the SCF ubiquitin ligase, SKP1, and FBXL10. GO:0140260 mitochondrial proton-transporting ATP synthase complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140260 Interacting selectively and non-covalently with a mitochondrial proton-transporting ATP synthase complex. GO:0140262 mRNA cap binding complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140262 Interacting selectively and non-covalently with a mRNA cap binding complex. GO:0140267 viral entry via permeabilization of host membrane biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0140267 The entry of a virus into the cytoplasm of a host cell, triggered by an interaction between the bilayer of a host membrane and a membrane-penetration capsid protein. Results in release of the virus contents into the host cell cytoplasm. GO:0140266 Woronin body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140266 Peroxisome-derived dense-core vesicle that seals septal pores upon hyphal lysis to prevent excessive cytoplasmic loss. It is specific to several genera of filamentous ascomycetes. UBERON:0016550 spinal cord column biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016550 UBERON:0016552 phlegm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016552 mucus produced in the respiratory tract. GO:0140259 PRC1 complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140259 Interacting selectively and non-covalently with a PRC1 complex. UBERON:0016554 white matter of midbrain biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016554 mesencephalic white matter A white matter that is part of the midbrain. UBERON:0016553 respiratory system mucus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016553 Any mucus produced by a mucosae of the respiratory system. This includes the mucus produced in the nasal cavity (nasal mucus) and mucus produced in the respiratory tract (phlegm). GO:0140250 regulation protein catabolic process at synapse biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0140250 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the synapse. GO:0140252 regulation protein catabolic process at postsynapse biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0140252 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the postsynapse. GO:0140251 regulation protein catabolic process at presynapse biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0140251 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the presynapse. GO:0140253 cell-cell fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140253 cell fusion|cell cell fusion A cellular process in which two or more cells combine together, their plasma membrane fusing, producing a single cell. In some cases, nuclei fuse, producing a polyploid cell, while in other cases, nuclei remain separate, producing a syncytium. GO:0140256 negative regulation of cellular response to phosphate starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140256 Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to phosphate starvation. GO:0140255 regulation of cellular response to phosphate starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140255 Any process that modulates the frequency, rate or extent of cellular response to phosphate starvation. CHEBI:45525 (R)-2-methylbutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_45525 UBERON:0016549 central nervous system white matter layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016549 white matter layer of neuraxis|CNS white matter layer|white matter layer A layer of of the central nervous system that is composed of white matter. CHEBI:45522 O-phospho-L-serine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_45522 UBERON:0016548 central nervous system gray matter layer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016548 CNS grey matter layer|CNS gray matter layer|grey matter layer of neuraxis|gray matter layer of neuraxis|grey matter layer A layer of of the central nervous system that is part of gray matter. UBERON:0016542 limbic cortex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016542 cortex of limbic lobe|gray matter of limbic lobe|limbic lobe cortex UBERON:0016545 pharyngeal ectoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016545 The external part of the developing pharynx that is made of ectoderm. During vertebrate development, pockets form in pharyngeal ectoderm between the pharyngeal arches. GO:0140282 carbon-nitrogen ligase activity on lipid II biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140282 RHEA:57928|EC:6.3.5.13 L-glutamate--lipid II transaminase activity|undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl pentapeptide amidotransferase (glutamine-hydrolyzing) activity|carbon-nitrogen ligase activity on lipid II Catalysis of the reaction: L-glutamine + lipid II + ATP + H2O = L-glutamate + beta-D-GlcNAc(1->4)-Mur2Ac(oyl-L-Ala-D-isoGln-L-Lys-D-Ala-D-Ala)-diphospho-di-trans,octa-cis-undecaprenol + ADP + phosphate. GO:0140285 endosome fission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140285 The process by which early and late endosomes undergo budding and fission reactions that separate regions destined for lysosomal degradation from carriers to be recycled to the plasma membrane. GO:0140284 endoplasmic reticulum-endosome membrane contact site biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140284 ER-endosome membrane contact site A contact site between the endoplasmic reticulum membrane and the endosome membrane. GO:0140289 protein mono-ADP-ribosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140289 The transfer, from NAD, of a single (mono) ADP-ribose molecule to protein amino acids. GO:0140288 GBAF complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140288 A SWI/SNF subcomplex that incorporates two mutually exclusive paralogs, GLTSCR1 (glioma tumor suppressor candidate region gene 1) or GLTSCR1L (GLTSCR1-like), BRD9 (bromodomain-containing 9) and the BAF subunits BAF155, BAF60, SS18, BAF53a, and BRG1/BRM. CHEBI:21557 N-acetyl-L-methionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21557 GO:0140281 positive regulation of mitotic division septum assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140281 up regulation of division septum formation involved in mitotic cell cycle|up-regulation of septin assembly and septum biosynthesis involved in mitotic cell cycle|activation of septin assembly and septum formation involved in mitotic cell cycle|positive regulation of mitotic division septum assembly|positive regulation of septin assembly and septum formation involved in mitotic cell cycle|up regulation of formation of division septum involved in mitotic cell cycle|up-regulation of mitotic division septum assembly|positive regulation of formation of division septum involved in mitotic cell cycle|activation of septin assembly and septum biosynthesis involved in mitotic cell cycle|up-regulation of septin assembly and septum formation involved in mitotic cell cycle|upregulation of division septum formation involved in mitotic cell cycle|positive regulation of septin assembly and septum biosynthesis involved in mitotic cell cycle|activation of formation of division septum involved in mitotic cell cycle|activation of mitotic division septum assembly|up regulation of septin assembly and septum biosynthesis involved in mitotic cell cycle|upregulation of septin assembly and septum formation involved in mitotic cell cycle|up-regulation of formation of division septum involved in mitotic cell cycle|up-regulation of division septum formation involved in mitotic cell cycle|up regulation of mitotic division septum assembly|upregulation of septin assembly and septum biosynthesis involved in mitotic cell cycle|activation of division septum formation involved in mitotic cell cycle|upregulation of formation of division septum involved in mitotic cell cycle|up regulation of septin assembly and septum formation involved in mitotic cell cycle|positive regulation of division septum formation involved in mitotic cell cycle Any process that activates or increases the frequency, rate or extent of mitotic division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. GO:0140280 negative regulation of mitotic division septum assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140280 down-regulation of septin assembly and septum formation involved in mitotic cell cycle|negative regulation of septin assembly and septum formation involved in mitotic cell cycle|down regulation of septin assembly and septum formation involved in mitotic cell cycle|down regulation of septin assembly and septum biosynthesis involved in mitotic cell cycle|downregulation of mitotic division septum assembly|negative regulation of septin assembly and septum biosynthesis involved in mitotic cell cycle|down-regulation of septin assembly and septum biosynthesis involved in mitotic cell cycle|inhibition of division septum formation involved in mitotic cell cycle|negative regulation of division septum formation involved in mitotic cell cycle|down-regulation of division septum formation involved in mitotic cell cycle|down regulation of mitotic division septum assembly|inhibition of septin assembly and septum formation involved in mitotic cell cycle|down regulation of formation of division septum involved in mitotic cell cycle|downregulation of septin assembly and septum biosynthesis involved in mitotic cell cycle|inhibition of formation of division septum involved in mitotic cell cycle|downregulation of formation of division septum involved in mitotic cell cycle|downregulation of division septum formation involved in mitotic cell cycle|downregulation of septin assembly and septum formation involved in mitotic cell cycle|down regulation of division septum formation involved in mitotic cell cycle|inhibition of septin assembly and septum biosynthesis involved in mitotic cell cycle|inhibition of mitotic division septum assembly|down-regulation of formation of division septum involved in mitotic cell cycle|negative regulation of formation of division septum involved in mitotic cell cycle|down-regulation of mitotic division septum assembly Any process that stops, prevents or reduces the frequency, rate or extent of mitotic division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. UBERON:0016530 parietal cortex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016530 parietal lobe cortex|parietal neocortex|cortex of parietal lobe|gray matter of parietal lobe Gray matter of the parietal region of the neocortex, located in the parietal lobe of gyrencephalic animals. It is continuous anteriorly with the frontal cortex, posteriorly with the occipital cortex and medially with the insular cortex and with the temporal cortex on the posterior/inferior border. CHEBI:21565 N-acetyl-L-valine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21565 UBERON:0016536 white matter of limbic lobe biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016536 A white matter of cerebral lobe that is part of a limbic lobe. GO:0140279 regulation of mitotic division septum assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140279 regulation of formation of division septum involved in mitotic cell cycle|regulation of division septum formation involved in mitotic cell cycle|regulation of septin assembly and septum biosynthesis involved in mitotic cell cycle|regulation of septin assembly and septum formation involved in mitotic cell cycle Any process that modulates the frequency, rate or extent of mitotic division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. UBERON:0016538 temporal cortex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016538 gray matter of temporal lobe|temporal lobe cortex|temporal neocortex|cortex of temporal lobe Gray matter of the temporal region of the neocortex, located in the temporal lobe in gyrencephalic animals UBERON:0016531 white matter of parietal lobe biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016531 A white matter of cerebral lobe that is part of a parietal lobe. UBERON:0016534 white matter of temporal lobe biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016534 A white matter of cerebral lobe that is part of a temporal lobe. GO:0140272 exogenous protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140272 Interacting selectively and non-covalently with any protein or protein complex from a different species, for example a pathogen molecule binding to a host protein (a complex of two or more proteins that may include other nonprotein molecules). CHEBI:3576 chanoclavine-I biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_3576 GO:0140271 hexose import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140271 The directed movement of hexose from outside of a cell, across the plasma membrane and into the cytosol. GO:0140274 repair of kinetochore microtubule attachment defect biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140274 repair of kinetochore microtubule attachment defects|correction of kinetochore microtubule attachment defects The cell cycle process where kinetochore microtubule attachment defects are corrected. GO:0140273 repair of mitotic kinetochore microtubule attachment defect biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140273 correction of mitotic kinetochore microtubule attachment defects|repair of mitotic kinetochore microtubule attachment defects The mitotic cell cycle process where kinetochore microtubule attachment defects are corrected. GO:0140276 obsolete pericentric heterochromatin maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140276 heterochromatin maintenance involved in chromatin silencing at centromeric outer repeats|heterochromatin maintenance involved in chromatin silencing at centromere outer repeat region|heterochromatin maintenance involved in chromatin silencing at pericentric region OBSOLETE. Any heterochromatin maintenance that is involved in chromatin silencing at or near a centromere. UBERON:0016529 cortex of cerebral lobe biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016529 neocortical part of cerebral hemisphere|cortex of lobe of cerebral hemisphere|gray matter of lobe of cerebral hemisphere|cortex of cerebral hemisphere lobe Grey matter neocortex region of a lobe of the cerebral hemisphere. GO:0140275 MIB complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140275 mitochondrial intermembrane space bridging complex|mitofilin complex A mitochondrial intermembrane space bridging complex consisting of components of the MICOS complex in the inner mitochondrial membrane, the SAM complex in the outer membrane, a conserved DNAJ protein (human DNAJC11) and Metaxin 1. UBERON:0016528 white matter of frontal lobe biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016528 frontal lobe white matter A white matter of cerebral lobe that is part of a frontal lobe. GO:0140278 mitotic division septum assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140278 The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following mitotic cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material. CHEBI:21569 N-acetyl-O-acetylneuraminic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21569 GO:0140270 gluconate import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140270 The directed movement of gluconate from outside of a cell, across the plasma membrane and into the cytosol. GO:0017040 N-acylsphingosine amidohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017040 MetaCyc:CERAMIDASE-RXN|Reactome:R-HSA-1606583|Reactome:R-HSA-1606602|RHEA:20856|Reactome:R-HSA-428205|EC:3.5.1.23|Reactome:R-HSA-428231 acylsphingosine deacylase activity|N-acylsphingosine amidohydrolase activity|glycosphingolipid ceramide deacylase Catalysis of the reaction: N-acylsphingosine + H2O = a fatty acid + sphingosine. GO:0032679 regulation of TRAIL production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032679 regulation of TRAIL biosynthetic process Any process that modulates the frequency, rate, or extent of TRAIL production. GO:0032678 regulation of interleukin-9 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032678 regulation of IL-9 production|regulation of interleukin-9 biosynthetic process Any process that modulates the frequency, rate, or extent of interleukin-9 production. GO:0032677 regulation of interleukin-8 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032677 regulation of IL-8 production|regulation of interleukin-8 biosynthetic process|regulation of interleukin-8 secretion Any process that modulates the frequency, rate, or extent of interleukin-8 production. GO:0042002 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042002 GO:0042001 hermaphrodite somatic sex determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042001 The determination of sex and sexual phenotypes in a hermaphroditic organism's soma. An example of this is found in Caenorhabditis elegans. GO:0042004 feminization of hermaphrodite soma biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042004 Promotion of female sex and sexual phenotypes in the hermaphroditic soma. An example of this is found in Caenorhabditis elegans. GO:0042003 masculinization of hermaphrodite soma biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042003 Promotion of male sex and sexual phenotypes in the hermaphroditic nematode soma. An example of this is found in Caenorhabditis elegans. GO:0042000 translocation of peptides or proteins into host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042000 transport of peptides or proteins into other organism during symbiotic interaction|translocation of peptides or proteins into other organism involved in symbiotic interaction|transport of peptides or proteins into host|translocation of peptides or proteins into other organism during symbiotic interaction The directed movement of peptides or proteins produced by an organism to a location inside its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0042009 interleukin-15 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042009 IL-15 binding Interacting selectively and non-covalently with interleukin-15. GO:0017039 obsolete dipeptidyl-peptidase III activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017039 DPP III activity|dipeptidyl-peptidase III activity|red cell angiotensinase activity|dipeptidyl arylamidase III activity|dipeptidyl aminopeptidase III activity|enkephalinase B activity OBSOLETE. Catalysis of the release of an N-terminal dipeptide from a peptide comprising four or more residues, with broad specificity; also acts on dipeptidyl 2-naphthylamides. GO:0042006 masculinization of hermaphroditic germ-line biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042006 The determination of male sex and sexual phenotype in the germ-line of the hermaphrodite. An example of this is found in Caenorhabditis elegans. GO:0017038 protein import biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017038 protein uptake The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event. GO:0042005 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042005 GO:0042008 interleukin-18 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042008 IL-18R|IL-18 receptor activity Combining with interleukin-18 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0042007 interleukin-18 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042007 IL-18 binding Interacting selectively and non-covalently with interleukin-18. GO:0017035 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0017035 GO:0032676 regulation of interleukin-7 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032676 regulation of interleukin-7 biosynthetic process|regulation of interleukin-7 secretion|regulation of IL-7 production Any process that modulates the frequency, rate, or extent of interleukin-7 production. CHEBI:3381 (-)-car-3-ene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_3381 GO:0032675 regulation of interleukin-6 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032675 regulation of interleukin-6 biosynthetic process|regulation of IL-6 production Any process that modulates the frequency, rate, or extent of interleukin-6 production. GO:0017034 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0017034 GO:0032674 regulation of interleukin-5 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032674 regulation of interleukin-5 biosynthetic process|regulation of interleukin-5 secretion|regulation of IL-5 production Any process that modulates the frequency, rate, or extent of interleukin-5 production. GO:0017037 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0017037 GO:0032673 regulation of interleukin-4 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032673 regulation of interleukin-4 biosynthetic process|regulation of interleukin-4 secretion|regulation of IL-4 production Any process that modulates the frequency, rate, or extent of interleukin-4 production. GO:0017036 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0017036 GO:0032672 regulation of interleukin-3 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032672 regulation of interleukin-3 biosynthetic process|regulation of IL-3 production Any process that modulates the frequency, rate, or extent of interleukin-3 production. GO:0017031 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0017031 GO:0017030 obsolete beta-galactosidase stabilization activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017030 beta-galactosidase stabilization activity OBSOLETE. Stabilization of the structure of beta-galactosidase. GO:0032671 regulation of interleukin-27 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032671 regulation of interleukin-27 synthesis|regulation of interleukin-27 formation|regulation of IL-27 production|regulation of interleukin-27 biosynthetic process Any process that modulates the frequency, rate, or extent of interleukin-27 production. GO:0032670 regulation of interleukin-26 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032670 regulation of IL-26 production|regulation of interleukin-26 biosynthetic process Any process that modulates the frequency, rate, or extent of interleukin-26 production. GO:0017033 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0017033 GO:0017032 amino acid:potassium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017032 potassium:amino acid symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + K+(out) = amino acid(in) + K+(in). GO:0017051 retinol dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017051 Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + retinol = adenosine 3',5'-bisphosphate + anhydroretinol. GO:0017050 D-erythro-sphingosine kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017050 Reactome:R-HSA-5218845|RHEA:35847|MetaCyc:RXN3DJ-11417|Reactome:R-HSA-9695949|Reactome:R-HSA-9625814|Reactome:R-HSA-428273 sphingosine kinase activity Catalysis of the reaction: sphingosine + ATP = sphingosine 1-phosphate + ADP. GO:0032669 regulation of interleukin-25 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032669 regulation of IL-25 production|regulation of interleukin-25 biosynthetic process|regulation of interleukin-25 secretion Any process that modulates the frequency, rate, or extent of interleukin-25 production. GO:0032668 regulation of interleukin-24 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032668 regulation of IL-24 production|regulation of interleukin-24 biosynthetic process Any process that modulates the frequency, rate, or extent of interleukin-24 production. GO:0032667 regulation of interleukin-23 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032667 regulation of interleukin-23 synthesis|regulation of interleukin-23 formation|regulation of interleukin-23 biosynthesis|regulation of interleukin-23 biosynthetic process|regulation of IL-23 production|regulation of IL-23 biosynthetic process|regulation of interleukin-23 anabolism Any process that modulates the frequency, rate, or extent of interleukin-23 production. GO:0032666 regulation of interleukin-22 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032666 regulation of IL-22 production|regulation of interleukin-22 biosynthetic process Any process that modulates the frequency, rate, or extent of interleukin-22 production. GO:0042013 interleukin-19 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042013 IL-19 binding Interacting selectively and non-covalently with interleukin-19. GO:0042012 interleukin-16 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042012 IL-16R|IL-16 receptor activity Combining with interleukin-16 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0042015 interleukin-20 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042015 IL-20 binding Interacting selectively and non-covalently with interleukin-20. GO:0042014 interleukin-19 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042014 IL-19 receptor activity|IL-19R Combining with interleukin-19 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0042011 interleukin-16 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042011 IL-16 binding Interacting selectively and non-covalently with interleukin-16. GO:0042010 interleukin-15 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042010 IL-15R|IL-15 receptor activity Combining with interleukin-15 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0042017 interleukin-22 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042017 IL-22 binding Interacting selectively and non-covalently with interleukin-22. GO:0042016 interleukin-20 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042016 IL-20 receptor activity|IL-20R Combining with interleukin-20 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0017049 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0017049 GO:0042019 interleukin-23 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042019 IL-23 binding Interacting selectively and non-covalently with interleukin-23. GO:0042018 interleukin-22 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042018 IL-22R|IL-22 receptor activity Combining with interleukin-22 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0032665 regulation of interleukin-21 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032665 regulation of IL-21 production|regulation of interleukin-21 biosynthetic process Any process that modulates the frequency, rate, or extent of interleukin-21 production. GO:0017046 peptide hormone binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017046 polypeptide hormone binding Interacting selectively and non-covalently with any peptide with hormonal activity in animals. CHEBI:3392 carbendazim biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_3392 GO:0032664 regulation of interleukin-20 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032664 regulation of IL-20 production|regulation of interleukin-20 biosynthetic process Any process that modulates the frequency, rate, or extent of interleukin-20 production. CHEBI:3391 carbazole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_3391 GO:0017045 corticotropin-releasing hormone activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017045 Wikipedia:Corticotropin-releasing_hormone adrenocorticotropin-releasing hormone The action characteristic of corticotropin-releasing hormone (CRH), any of a number of peptides released by the mammalian hypothalamus into the hypophyseal-portal circulation in response to neural and/or chemical stimuli. Upon receptor binding, CRH increases the rate of corticotropin secretion by the anterior pituitary. GO:0032663 regulation of interleukin-2 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032663 regulation of interleukin-2 secretion|regulation of IL-2 production|regulation of interleukin-2 biosynthetic process Any process that modulates the frequency, rate, or extent of interleukin-2 production. GO:0017048 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0017048 GO:0017047 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0017047 GO:0032662 regulation of interleukin-19 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032662 regulation of IL-19 production|regulation of interleukin-19 biosynthetic process Any process that modulates the frequency, rate, or extent of interleukin-19 production. GO:0017042 glycosylceramidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017042 MetaCyc:GLYCOSYLCERAMIDASE-RXN|EC:3.2.1.62 phlorizin hydrolase activity|glycosyl-N-acylsphingosine glycohydrolase activity|phloridzin glucosidase activity|cerebrosidase activity|lactase-phlorizin hydrolase|phloridzin beta-glucosidase activity|glycosyl ceramide glycosylhydrolase activity|phloretin-glucosidase activity Catalysis of the reaction: glycosyl-N-acylsphingosine + H2O = a sugar + N-acylsphingosine. GO:0032661 regulation of interleukin-18 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032661 regulation of interleukin-18 biosynthetic process|regulation of IL-18 production|regulation of interleukin-18 secretion Any process that modulates the frequency, rate, or extent of interleukin-18 production. GO:0032660 regulation of interleukin-17 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032660 regulation of CTLA-8 production|regulation of IL-17 production|regulation of interleukin-17 biosynthetic process|regulation of interleukin-17 secretion|regulation of Cytotoxic T-lymphocyte-associated antigen 8 secretion Any process that modulates the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines. GO:0017041 galactosylgalactosylglucosylceramidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017041 MetaCyc:3.2.1.47-RXN|EC:3.2.1.47|RHEA:21112 ceramidetrihexoside alpha-galactosidase activity|D-galactosyl-D-galactosyl-D-glucosyl-N-acylsphingosine galactohydrolase activity|ceramide trihexosidase activity|ceramidetrihexosidase activity|trihexosylceramide alpha-galactosidase activity|trihexosyl ceramide galactosidase activity Catalysis of the reaction: D-galactosyl-D-galactosyl-D-glucosyl-N-acylsphingosine + H2O = lactosyl-N-acylsphingosine + D-galactose. GO:0017044 melanocyte-stimulating hormone activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017044 alpha-melanocyte stimulating hormone activity|alpha-melanophore stimulating hormone activity|melanocyte stimulating hormone activity The action characteristic of melanocyte-stimulating hormone, any of three peptide hormones that are produced by the intermediate lobe of the pituitary gland and, upon receptor binding, cause dispersal of melanosomes in melanophores of poikilothermic vertebrates. GO:0017043 obsolete adrenocorticotropin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017043 corticotropin|adrenocorticotropin OBSOLETE. A polypeptide hormone which stimulates the adrenal cortex to synthesize and secrete glucocorticoid hormones. GO:0032659 regulation of interleukin-16 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032659 regulation of IL-16 production|regulation of interleukin-16 biosynthetic process Any process that modulates the frequency, rate, or extent of interleukin-16 production. GO:0032658 regulation of interleukin-15 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032658 regulation of interleukin-15 biosynthetic process|regulation of IL-15 production Any process that modulates the frequency, rate, or extent of interleukin-15 production. GO:0032657 regulation of interleukin-14 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032657 regulation of IL-14 production|regulation of interleukin-14 biosynthetic process Any process that modulates the frequency, rate, or extent of interleukin-14 production. GO:0032656 regulation of interleukin-13 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032656 regulation of interleukin-13 secretion|regulation of IL-13 production|regulation of interleukin-13 biosynthetic process Any process that modulates the frequency, rate, or extent of interleukin-13 production. GO:0032655 regulation of interleukin-12 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032655 regulation of NKSF production|regulation of interleukin-12 secretion|regulation of CLMF production|regulation of interleukin-12 biosynthetic process|regulation of IL-12 production Any process that modulates the frequency, rate, or extent of interleukin-12 production. GO:0042024 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042024 GO:0042023 DNA endoreduplication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042023 DNA endoreplication|DNA re-duplication Regulated re-replication of DNA within a single cell cycle, resulting in an increased cell ploidy. An example of this process occurs in the synthesis of Drosophila salivary gland cell polytene chromosomes. GO:0042026 protein refolding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042026 heat shock protein activity The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones. GO:0042025 host cell nucleus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042025 A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0042020 interleukin-23 receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042020 IL-23R|IL-23 receptor activity Combining with interleukin-23 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0042022 interleukin-12 receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042022 IL-12 receptor complex|IL12RB1-IL12RB2 complex A protein complex that binds interleukin-12 and that consists of, at a minimum, a dimeric interleukin and its two receptor subunits as well as optional additional kinase subunits. GO:0042021 granulocyte macrophage colony-stimulating factor complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042021 granulocyte macrophage colony stimulating factor complex binding|GM-CSF complex binding|GMC-SF complex binding Interacting selectively and non-covalently with the granulocyte macrophage colony-stimulating factor complex. GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017017 dual-specificity MAP kinase phosphatase activity Catalysis of the reaction: MAP kinase serine/threonine/tyrosine phosphate + H2O = MAP kinase serine/threonine/tyrosine + phosphate. GO:0042028 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042028 GO:0017016 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0017016 GO:0042027 obsolete cyclophilin-type peptidyl-prolyl cis-trans isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042027 cyclophilin-type peptidyl-prolyl cis-trans isomerase activity OBSOLETE. Catalysis of the reaction: peptidylproline (omega=180) = peptidylproline (omega=0). GO:0017019 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0017019 GO:0042029 obsolete fibrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042029 fibrolase activity|fibrinolytic proteinase activity|Agkistrodon contortrix contortrix venom metalloproteinase activity|Agkistrodon contortrix contortrix metalloproteinase activity OBSOLETE. Catalysis of the cleavage of 14-Ala-Leu-15 in insulin B chain and cleavage of 413-Lys-Leu-414 in alpha chain of fibrinogen. GO:0017018 myosin phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017018 Reactome:R-HSA-390593|Reactome:R-HSA-445699 myosin phosphatase myosin binding|myosin phosphatase, intrinsic catalyst activity Catalysis of the reaction: phosphomyosin + H2O = myosin + phosphate. GO:0032654 regulation of interleukin-11 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032654 regulation of interleukin-11 secretion|regulation of IL-11 production|regulation of interleukin-11 biosynthetic process Any process that modulates the frequency, rate, or extent of interleukin-11 production. GO:0017013 protein flavinylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017013 protein amino acid flavinylation The addition of a flavin group to a protein amino acid. GO:0017012 protein-phytochromobilin linkage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017012 RESID:AA0133 The linkage of the chromophore phytochromobilin to phycocyanin or allophycocyanin. GO:0032653 regulation of interleukin-10 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032653 regulation of interleukin-10 secretion|regulation of interleukin-10 biosynthetic process|regulation of IL-10 production Any process that modulates the frequency, rate, or extent of interleukin-10 production. GO:0017015 regulation of transforming growth factor beta receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017015 regulation of TGF-beta receptor signaling pathway|regulation of TGFbeta receptor signaling pathway|regulation of transforming growth factor beta receptor signalling pathway Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway. GO:0032652 regulation of interleukin-1 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032652 regulation of interleukin-1 biosynthetic process|regulation of IL-1 production|regulation of interleukin-1 secretion Any process that modulates the frequency, rate, or extent of interleukin-1 production. GO:0017014 protein nitrosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017014 protein amino acid nitrosylation The covalent addition of a nitric oxide group to an amino acid within a protein. GO:0032651 regulation of interleukin-1 beta production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032651 regulation of interleukin-1 beta secretion|regulation of interleukin-1 beta biosynthetic process|regulation of IL-1 beta production Any process that modulates the frequency, rate, or extent of interleukin-1 beta production. GO:0032650 regulation of interleukin-1 alpha production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032650 regulation of interleukin-1 alpha biosynthetic process|regulation of IL-1 alpha production|regulation of interleukin-1 alpha secretion Any process that modulates the frequency, rate, or extent of interleukin-1 alpha production. CHEBI:3362 canthaxanthin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_3362 GO:0017011 protein-phycoerythrobilin linkage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017011 RESID:AA0132 The linkage of the chromophore phycoerythrobilin to phycoerythrins. GO:0017010 protein-phycourobilin linkage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017010 RESID:AA0260 The linkage of the chromophore phycourobilin to phycoerythrins. GO:0032649 regulation of interferon-gamma production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032649 regulation of interferon-gamma biosynthetic process|regulation of type II interferon production|regulation of interferon-gamma secretion Any process that modulates the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon. GO:0032648 regulation of interferon-beta production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032648 regulation of interferon-beta biosynthetic process|regulation of IFN-beta production|regulation of interferon-beta secretion Any process that modulates the frequency, rate, or extent of interferon-beta production. GO:0032647 regulation of interferon-alpha production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032647 regulation of interferon-alpha biosynthetic process|regulation of interferon-alpha secretion Any process that modulates the frequency, rate, or extent of interferon-alpha production. GO:0032646 regulation of hepatocyte growth factor production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032646 regulation of hepatocyte growth factor biosynthetic process|regulation of HGF production|regulation of scatter factor production Any process that modulates the frequency, rate, or extent of hepatocyte growth factor production. GO:0032645 regulation of granulocyte macrophage colony-stimulating factor production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032645 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process|regulation of GM-CSF production|regulation of granulocyte macrophage colony stimulating factor production Any process that modulates the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production. GO:0032644 regulation of fractalkine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032644 regulation of CX3CL1 production|regulation of fractalkine biosynthetic process|regulation of CX3CL1 biosynthesis Any process that modulates the frequency, rate, or extent of fractalkine production. GO:0042035 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042035 GO:0042034 peptidyl-L-lysine methyl ester biosynthetic process from peptidyl-lysine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042034 RESID:AA0318 peptidyl-lysine esterification The modification of a C-terminal peptidyl-lysine to form peptidyl-L-lysine methyl ester. GO:0042037 peptidyl-histidine methylation, to form pros-methylhistidine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042037 RESID:AA0073 peptidyl-histidine pros-methylation The methylation of peptidyl-L-histidine to form peptidyl-L-3'-methyl-L-histidine (otherwise known as pi-methylhistidine, pros-methylhistidine). GO:0042036 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042036 GO:0042031 obsolete angiotensin-converting enzyme inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042031 ACE inhibitor|peptidyl dipeptidase A inhibitor|angiotensin-converting enzyme inhibitor activity OBSOLETE. Stops, prevents or reduces the activity of angiotensin-converting enzyme, thereby preventing the synthesis of angiotensin II from its precursor, angiotensin I. GO:0042030 ATPase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042030 adenosinetriphosphatase inhibitor Stops, prevents or reduces the activity of any enzyme that catalyzes the hydrolysis of ATP to ADP and orthophosphate. GO:0042033 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042033 GO:0042032 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042032 CHEBI:3378 capsorubin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_3378 GO:0017028 obsolete protein stabilization activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017028 protein stabilization activity OBSOLETE. Strengthening of a bond between proteins. Proteins are large molecules composed of one or more chains of amino acids. The amino acids are joined in a specific order by peptide bonds. GO:0042039 vanadium incorporation into metallo-sulfur cluster biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042039 vanadium incorporation into metallo-sulphur cluster The incorporation of vanadium a metallo-sulfur cluster such as VFe(7-8)S(n). GO:0017027 obsolete transmembrane receptor protein serine/threonine kinase receptor-associated protein activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017027 transmembrane receptor protein serine/threonine kinase receptor-associated protein activity OBSOLETE. (Was not defined before being made obsolete). GO:0042038 peptidyl-histidine methylation, to form tele-methylhistidine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042038 RESID:AA0317 peptidyl-histidine tele-methylation The methylation of peptidyl-L-histidine to form peptidyl-L-1'-methyl-L-histidine (otherwise known as tau-methylhistidine, tele-methylhistidine). GO:0017029 obsolete lysosomal protein stabilization biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017029 lysosomal protein stabilization OBSOLETE. (Was not defined before being made obsolete). GO:0032643 regulation of connective tissue growth factor production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032643 regulation of hypertrophic chondrocyte-specific gene product 24 production|regulation of connective tissue growth factor biosynthetic process|regulation of Fisp12 production|regulation of IGFBP8 production|regulation of CCN2 production|regulation of CTGF production|regulation of Hcs24 production Any process that modulates the frequency, rate, or extent of connective tissue growth factor production. GO:0017024 myosin I binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017024 Interacting selectively and non-covalently with a class I myosin; myosin I heavy chains are single-headed, possess tails of various lengths, and do not self-associate into bipolar filaments. GO:0017023 myosin phosphatase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0017023 An enzyme complex that catalyzes the removal of the phosphate group from phosphomyosin. GO:0032642 regulation of chemokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032642 regulation of chemokine secretion|regulation of chemokine biosynthetic process Any process that modulates the frequency, rate, or extent of chemokine production. GO:0017026 obsolete procollagen C-endopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017026 BMP1|procollagen C-terminal peptidase activity|procollagen C-endopeptidase activity|carboxyprocollagen peptidase activity|procollagen peptidase activity|procollagen carboxy-terminal proteinase activity|procollagen C-proteinase activity|procollagen C-terminal proteinase activity|procollagen carboxypeptidase activity OBSOLETE. Catalysis of the cleavage of the C-terminal propeptide at Ala-Asp in type I and II procollagens and at Arg-Asp in type III. GO:0032641 lymphotoxin A production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032641 TNF-beta production|lymphotoxin A biosynthetic process|tumor necrosis factor-beta production|lymphotoxin A synthesis|LTA production|lymphotoxin-alpha production|lymphotoxin A formation|TNF-B production The chemical reactions and pathways resulting in the formation of the cytokine lymphotoxin A. GO:0032640 tumor necrosis factor production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032640 TNF alpha biosynthesis|tumor necrosis factor biosynthetic process|tumor necrosis factor secretion|tumor necrosis factor anabolism|tumor necrosis factor biosynthesis|TNF biosynthetic process|TNF biosynthesis|tumor necrosis factor synthesis|cachectin production|tumor necrosis factor formation|Tnfa production|tumor necrosis factor-alpha production|TNF-alpha production|TNF-alpha biosynthetic process|TNF-alpha biosynthesis|TNF production The appearance of tumor necrosis factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Tumor necrosis factor is an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis. GO:0017025 TBP-class protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017025 TBP binding|TBP-related factor (TRF) protein binding|TATA-binding protein binding Interacting selectively and non-covalently with a member of the class of TATA-binding proteins (TBP), including any of the TBP-related factors (TRFs). GO:0017020 myosin phosphatase regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017020 myosin phosphatase, intrinsic regulator activity Modulation of the activity of the enzyme myosin phosphatase. GO:0017022 myosin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017022 myosin phosphatase myosin binding Interacting selectively and non-covalently with any part of a myosin complex; myosins are any of a superfamily of molecular motor proteins that bind to actin and use the energy of ATP hydrolysis to generate force and movement along actin filaments. GO:0017021 obsolete myosin phosphatase myosin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017021 myosin phosphatase myosin binding OBSOLETE. (Was not defined before being made obsolete). CHEBI:3375 capsanthin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_3375 GO:0032639 TRAIL production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032639 TRAIL biosynthetic process The appearance of TRAIL due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0042040 metal incorporation into metallo-molybdopterin complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042040 The incorporation of a metal into a metallo-molybdopterin complex. GO:0032638 interleukin-9 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032638 interleukin-9 secretion|interleukin-9 biosynthetic process|IL-9 production The appearance of interleukin-9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0032637 interleukin-8 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032637 interleukin-8 secretion|interleukin-8 biosynthetic process|IL-8 production The appearance of interleukin-8 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0032636 interleukin-7 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032636 interleukin-7 biosynthetic process|interleukin-7 secretion|IL-7 production The appearance of interleukin-7 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0032635 interleukin-6 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032635 interleukin-6 biosynthetic process|interleukin-6 secretion|IL-6 production The appearance of interleukin-6 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0032634 interleukin-5 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032634 interleukin-5 biosynthetic process|interleukin-5 secretion|IL-5 production The appearance of interleukin-5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0032633 interleukin-4 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032633 interleukin-4 biosynthetic process|interleukin-4 secretion|IL-4 production The appearance of interleukin-4 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0042046 W-molybdopterin cofactor metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042046 Moco metabolism|W-molybdopterin cofactor metabolism|Moco metabolic process The chemical reactions and pathways involving the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands. GO:0042045 epithelial fluid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042045 The directed movement of fluid across epithelia. GO:0042048 olfactory behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042048 behavioral response to scent|behavioural response to smell|olfactory behaviour|behavioral response to smell|behavioural response to scent|behavioural response to odour The behavior of an organism in response to an odor. GO:0042047 W-molybdopterin cofactor biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042047 W-molybdopterin cofactor synthesis|W-molybdopterin cofactor biosynthesis|W-molybdopterin cofactor formation|W-molybdopterin cofactor anabolism|Moco biosynthetic process|Moco biosynthesis The chemical reactions and pathways resulting in the formation of the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands. GO:0042042 tungsten incorporation into tungsten-molybdopterin complex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042042 The incorporation of tungsten into a tungsten-molybdopterin complex. GO:0042041 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042041 GO:0042044 fluid transport biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0042044 The directed movement of substances that are in liquid form in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0042043 neurexin family protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042043 neuroligin Interacting selectively and non-covalently with neurexins, synaptic cell surface proteins related to latrotoxin receptor, laminin and agrin. Neurexins act as cell recognition molecules at nerve terminals. GO:0042049 cellular acyl-CoA homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042049 cell acyl-CoA homeostasis Any process involved in the maintenance of an internal steady state of acyl-CoA within a cell or between a cell and its external environment. GO:0032632 interleukin-3 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032632 interleukin-3 biosynthetic process|interleukin-3 secretion|IL-3 production The appearance of interleukin-3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0032631 interleukin-27 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032631 interleukin-27 synthesis|interleukin-27 formation|interleukin-27 biosynthetic process|IL-27 production|interleukin-27 secretion The appearance of interleukin-27 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0032630 interleukin-26 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032630 interleukin-26 synthesis|interleukin-26 formation|AK155 secretion|interleukin-26 biosynthetic process|interleukin-26 biosynthesis|IL-26 production|interleukin-26 anabolism|interleukin-26 secretion The appearance of interleukin-26 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. UBERON:0006800 anatomical line biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006800 Non-material anatomical entity of one dimension, which forms a boundary of an anatomical surface or is a modulation of an anatomical surface. GO:0032629 interleukin-25 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032629 interleukin-25 biosynthetic process|interleukin-25 biosynthesis|IL-25 production|IL17E secretion|interleukin-25 secretion|interleukin-25 anabolism|IL-25 secretion|interleukin-25 synthesis|interleukin-25 formation The appearance of interleukin-25 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0032628 interleukin-24 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032628 interleukin-24 biosynthetic process|IL-24 production|ST16 production|MDA7 production|interleukin-24 secretion The appearance of interleukin-24 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0032627 interleukin-23 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032627 IL-23 production|interleukin-23 secretion|interleukin-23 biosynthetic process The appearance of interleukin-23 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0042051 compound eye photoreceptor development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042051 adult eye photoreceptor development The process whose specific outcome is the progression of a light-responsive receptor in the compound eye over time, from its formation to the mature structure. GO:0032626 interleukin-22 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032626 IL-22 production|IL22 production|ZCYTO18 production|ILTIF production|interleukin-22 secretion|interleukin-22 biosynthetic process The appearance of interleukin-22 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0042050 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042050 GO:0032625 interleukin-21 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032625 IL-21 production|interleukin-21 secretion|interleukin-21 biosynthetic process The appearance of interleukin-21 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0032624 interleukin-20 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032624 IL-20 production|ZCYTO10 production|interleukin-20 secretion|interleukin-20 biosynthetic process The appearance of interleukin-20 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0032623 interleukin-2 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032623 interleukin-2 biosynthetic process|interleukin-2 secretion|IL-2 production The appearance of interleukin-2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0032622 interleukin-19 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032622 ZMDA1 secretion|interleukin-19 biosynthetic process|IL-19 production|interleukin-19 secretion|IL-19 secretion The appearance of interleukin-19 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. CHEBI:127547 19-(4-hydroxyphenyl)nonadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_127547 GO:0042057 obsolete transforming growth factor beta receptor anchoring activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042057 transforming growth factor beta receptor anchoring activity|TGF-beta receptor anchoring activity|TGFbeta receptor anchoring activity|transforming growth factor beta receptor anchor activity OBSOLETE. Binds to transforming growth factor beta receptor and anchors it to a particular subcellular location. GO:0042056 chemoattractant activity biolink:MolecularActivity go-plus goslim_chembl|goslim_pir http://purl.obolibrary.org/obo/GO_0042056 attractant Providing the environmental signal that initiates the directed movement of a motile cell or organism towards a higher concentration of that signal. GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042059 negative regulation of EGF receptor signaling pathway|negative regulation of EGF receptor signalling pathway|down-regulation of epidermal growth factor receptor signaling pathway|negative regulation of EGFR signaling pathway|downregulation of epidermal growth factor receptor signaling pathway|down regulation of epidermal growth factor receptor signaling pathway|inhibition of epidermal growth factor receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity. GO:0042058 regulation of epidermal growth factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042058 regulation of EGF receptor signalling pathway|regulation of EGF receptor signaling pathway|regulation of EGFR signaling pathway Any process that modulates the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity. GO:0042053 regulation of dopamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042053 regulation of dopamine metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving dopamine. GO:0042052 rhabdomere development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042052 rhabdomere organization The assembly and arrangement of a rhabdomere within a cell. The rhabdomere is the organelle on the apical surface of a photoreceptor cell that contains the visual pigments. GO:0042055 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042055 GO:0042054 histone methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042054 histone methylase activity Catalysis of the reaction: S-adenosyl-L-methionine + histone = S-adenosyl-L-homocysteine + methyl-histone. Histone methylation generally occurs on either an arginine or lysine residue. GO:0017009 protein-phycocyanobilin linkage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017009 RESID:AA0131 The linkage of the chromophore phycocyanobilin to phycocyanin or allophycocyanin. GO:0017006 protein-tetrapyrrole linkage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017006 The covalent linking of a tetrapyrrole to a protein. GO:0017005 3'-tyrosyl-DNA phosphodiesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017005 Catalysis of the hydrolysis of 3'-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase I and DNA. GO:0017008 protein-phycobiliviolin linkage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017008 RESID:AA0258 The linkage of the chromophore phycobiliviolin to phycoerythrocyanin. GO:0017007 protein-bilin linkage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017007 The covalent linkage of bilin and a protein. GO:0032621 interleukin-18 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032621 IGIF production|interleukin-18 biosynthetic process|IL-18 production|interleukin-18 secretion|IL1F4 production The appearance of interleukin-18 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0017002 activin-activated receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017002 activin receptor activity Combining with activin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Activin is one of two gonadal glycoproteins related to transforming growth factor beta. GO:0032620 interleukin-17 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032620 interleukin-17 biosynthetic process|IL-17 production|Cytotoxic T-lymphocyte-associated antigen 8 production|interleukin-17 secretion|CTLA-8 production The appearance of any member of the interleukin-17 family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0017001 antibiotic catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017001 antibiotic degradation|antibiotic breakdown|antibiotic catabolism The chemical reactions and pathways resulting in the breakdown of antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms. GO:0017004 cytochrome complex assembly biolink:BiologicalProcess go-plus goslim_metagenomics http://purl.obolibrary.org/obo/GO_0017004 cytochrome biogenesis The aggregation, arrangement and bonding together of a cytochrome complex. A cytochrome complex is a protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions. GO:0017003 protein-heme linkage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017003 protein-haem linkage The covalent linkage of heme and a protein. GO:0017000 antibiotic biosynthetic process biolink:BiologicalProcess go-plus goslim_metagenomics http://purl.obolibrary.org/obo/GO_0017000 antibiotic biosynthesis|antibiotic anabolism|antibiotic synthesis|antibiotic formation The chemical reactions and pathways resulting in the formation of an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms. GO:0042060 wound healing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042060 Wikipedia:Wound_healing The series of events that restore integrity to a damaged tissue, following an injury. GO:0032618 interleukin-15 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032618 interleukin-15 secretion|interleukin-15 biosynthetic process|IL-15 production The appearance of interleukin-15 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0032617 interleukin-14 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032617 interleukin-14 secretion|interleukin-14 biosynthetic process|IL-14 production The appearance of interleukin-14 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0032616 interleukin-13 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032616 interleukin-13 secretion|interleukin-13 biosynthetic process|IL-13 production The appearance of interleukin-13 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0042062 long-term strengthening of neuromuscular junction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042062 Any process that results in an increase in the efficacy of transmission at a neuromuscular synapse. GO:0032615 interleukin-12 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032615 NKSF production|interleukin-12 secretion|interleukin-12 biosynthetic process|IL-12 production|CLMF production The appearance of interleukin-12 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0042061 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042061 GO:0032614 interleukin-11 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032614 interleukin-11 secretion|interleukin-11 biosynthetic process|IL-11 production The appearance of interleukin-11 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0032613 interleukin-10 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032613 interleukin-10 secretion|interleukin-10 biosynthetic process|IL-10 production The appearance of interleukin-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0032612 interleukin-1 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032612 interleukin-1 biosynthetic process|interleukin-1 secretion|IL-1 production The appearance of interleukin-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0032611 interleukin-1 beta production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032611 interleukin-1 beta secretion|interleukin-1 beta biosynthetic process|IL-1 beta production The appearance of interleukin-1 beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0042068 regulation of pteridine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042068 regulation of pteridine metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving pteridine. GO:0042067 establishment of ommatidial planar polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042067 establishment of ommatidial polarity The specification of polarized ommatidia. Ommatidia occur in two chiral forms. The trapezoidal arrangement of photoreceptors in the dorsal part of the eye is the mirror image of that in the ventral part. GO:0042069 regulation of catecholamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042069 regulation of catecholamine metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catecholamines. GO:0042064 obsolete cell adhesion receptor regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042064 cell adhesion receptor regulator activity OBSOLETE. (Was not defined before being made obsolete). CHEBI:45487 13-cis-retinal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_45487 GO:0042063 gliogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042063 glial cell generation The process that results in the generation of glial cells. This includes the production of glial progenitors and their differentiation into mature glia. GO:0042066 perineurial glial growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042066 Glial cell growth that occurs in the perineurium, a cell layer that ensheaths projections of peripheral nerves, such as motor axons. GO:0032619 interleukin-16 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032619 LCF production|interleukin-16 secretion|interleukin-16 biosynthetic process|IL-16 production|pro-interleukin-16 production The appearance of interleukin-16 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0042065 glial cell growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042065 Growth of glial cells, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system. GO:0032610 interleukin-1 alpha production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032610 interleukin-1 alpha biosynthetic process|IL-1 alpha production|interleukin-1 alpha secretion The appearance of interleukin-1 alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0032607 interferon-alpha production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032607 IFN-alpha production|interferon-alpha biosynthetic process|IFNA production|interferon-alpha secretion The appearance of interferon-alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0042071 leucokinin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042071 Combining with a leucokinin, any of several octapeptide hormones found in insects, and transmitting the signal to initiate a change in cell activity. GO:0042070 maintenance of oocyte nucleus location involved in oocyte dorsal/ventral axis specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042070 oocyte axis determination, maintenance of oocyte nucleus position|maintenance of oocyte nucleus location involved in oocyte dorsal-ventral axis specification|oocyte axis determination, oocyte nucleus anchoring|oocyte nucleus anchoring during oocyte axis determination|maintenance of oocyte nucleus location involved in oocyte dorsal/ventral axis determination|oocyte axis determination, maintenance of oocyte nucleus localization|maintenance of oocyte nucleus location involved in oocyte dorsoventral axis specification|maintenance of oocyte nucleus position during oocyte axis determination|maintenance of oocyte nucleus localization during oocyte axis determination Maintenance of the oocyte nucleus in a particular position within the cell during the establishment and maintenance of the axes of the oocyte. An example of this process is found In Drosophila melanogaster. GO:0032606 type I interferon production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032606 type I interferon secretion|interferon type I production|type I IFN production|type I interferon biosynthetic process The appearance of type I interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. GO:0042073 intraciliary transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042073 Wikipedia:Intraflagellar_transport intraflagellar transport|IFT|intraflagellar transport involved in cilium organization|intraflagellar transport involved in microtubule-based flagellum organisation The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins. GO:0032605 hepatocyte growth factor production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032605 HGF production|scatter factor production|hepatocyte growth factor biosynthetic process The appearance of hepatocyte growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0032604 granulocyte macrophage colony-stimulating factor production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032604 granulocyte macrophage colony-stimulating factor biosynthetic process|GM-CSF production|granulocyte macrophage colony stimulating factor production The appearance of granulocyte macrophage colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0042072 obsolete cell adhesion receptor inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042072 cell adhesion receptor inhibitor activity OBSOLETE. (Was not defined before being made obsolete). GO:0032603 fractalkine production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032603 ABCD-3 production|CX3CL1 production|fractalkine metabolic process|fractalkine biosynthetic process|neurotactin production The appearance of fractalkine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0032602 chemokine production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032602 chemokine anabolism|chemokine synthesis|chemokine formation|chemokine metabolic process|chemokine biosynthetic process|chemokine secretion|chemokine biosynthesis The appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria. GO:0032601 connective tissue growth factor production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032601 CTGF production|Hcs24 production|Fisp12 production|hypertrophic chondrocyte-specific gene product 24 production|IGFBP8 production|CCN2 production The appearance of connective tissue growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0032600 chemokine receptor transport out of membrane raft biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032600 chemokine receptor translocation out of membrane raft|chemokine receptor transport out of lipid raft The directed movement of a chemokine receptor out of a membrane raft. GO:0042079 obsolete GPI/GSI anchor metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042079 GPI/GSI anchor metabolic process OBSOLETE. (Was not defined before being made obsolete). GO:0042078 germ-line stem cell division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042078 germ-line stem cell renewal The self-renewing division of a germline stem cell to produce a daughter stem cell and a daughter germ cell, which will divide to form the gametes. CHEBI:45479 13-cis-retinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_45479 GO:0042075 nickel incorporation into nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042075 RESID:AA0310 nickel incorporation into nickel-iron-sulphur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulphide The incorporation of nickel into a nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide, found in carbon monoxide dehydrogenase. GO:0042074 cell migration involved in gastrulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042074 The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression). GO:0042077 protein phosphate-linked glycosylation via serine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042077 protein amino acid phosphate-linked glycosylation via serine The glycosylation of peptidyl-serine through a phosphoester bond forming, for example, GlcNAc-alpha-1-P-Ser residues. GO:0032609 interferon-gamma production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032609 type II IFN production|interferon-gamma secretion|interferon-gamma biosynthetic process|IFNG production|type II interferon production The appearance of interferon-gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon-gamma is also known as type II interferon. GO:0032608 interferon-beta production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032608 IFN-beta production|interferon-beta biosynthetic process|interferon-beta secretion|IFNB production The appearance of interferon-beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0042076 protein phosphate-linked glycosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042076 phosphoglycosylation|protein amino acid phosphate-linked glycosylation The glycosylation of peptidyl-amino acids through a phosphoester bond forming, for example, GlcNAc-alpha-1-P-Ser residues. GO:0140507 granzyme-mediated programmed cell death signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140507 granzyme-mediated cell death signaling pathway A series of molecular signals induced by granzymes which triggers the cell death of a cell. The pathway starts with reception of a granzyme signal, and ends when the execution phase of cell death is triggered. Granzymes are serine proteases that are secreted by cytotoxic T cells and natural killer cells to induce cell death in target cells. GO:0140509 epithelium-like organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140509 The organization of a polarized cell layer during morphogenesis in protozoa; an example is found during culmination in D. discoideum, involving alpha and beta catenins. GO:0140500 regulation of reticulophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140500 regulation of ER-phagy|regulation of ER autophagy|regulation of endoplasmic reticulum autophagy|regulation of ER degradation|regulation of autophagy of the ER|regulation of autophagy of the endoplasmic reticulum|regulation of endoplasmic reticulum degradation Any process that modulates the frequency, rate or extent of reticulophagy. GO:0140502 effector-mediated suppression of host salicylic acid-mediated innate immune signalling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140502 A process mediated by a molecule secreted by a symbiont that results in the suppression of host salicylic acid-mediated innate immune signalling. GO:0140501 positive regulation of reticulophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140501 positive regulation of autophagy of the ER|positive regulation of endoplasmic reticulum degradation|positive regulation of ER-phagy|positive regulation of ER autophagy|positive regulation of ER degradation|positive regulation of autophagy of the endoplasmic reticulum|positive regulation of endoplasmic reticulum autophagy Any process that increases the frequency, rate or extent of reticulophagy. GO:0140504 microlipophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140504 lipid droplet autophagy Microautophagy-mediated direct internalization of lipid droplets into a lysosome-like vacuole during nutrient depletion, such as during the transition to stationary phase or in response to nutrient limitation. Microlipophagy is mediated by the formation of sterol-enriched vacuolar microdomains at sites of engulfment. Initiation of microautophagy is defined as the point where liquid-ordered microdomains are formed at sites of engulfment, that requires S. cerevisiae Atg32p and Atg21p, as well as Niemann-Pick type C (NPC) sterol transporter proteins, Ncr1p and Npc2p. This is followed by redistribution of Atg14p from ER exit sites onto liquid-ordered vacuole membrane domains through interaction with stabilized AMP-activated protein kinase (AMPK), and together with Atg6p facilities docking and internalization of lipid droplets (LDs) at sites of invagination. GO:0140506 endoplasmic reticulum-autophagosome adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140506 autophagosome-ER anchor|ER- autophagosome anchor|autophagosome-endoplasmic reticulum anchor The binding activity of a molecule that brings together an ER membrane and an autophagosome during reticulophagy. GO:0140505 regulation of microlipophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140505 Any process that modulates the frequency, rate or extent of microlipophagy, the microautophagy-mediated direct internalization of lipid droplets into a lysosome-like vacuole during nutrient depletion. GO:0140529 CMG complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140529 The aggregation, arrangement and bonding together of a set of components to form the CMG complex, a protein complex that contains the GINS complex, Cdc45p, and the heterohexameric MCM complex, and that is involved in unwinding DNA during replication. The process begins when additional proteins (e.g. Cdc45 and Sld3) join the loaded, inactive double MCM hexamer at replication origins, and ends when Mcm10 triggers the separation of the Mcm2-7 double hexamers, forming two active CMG complexes. GO:0140522 fusogenic activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140522 The activity of joining two lipid bilayers to form a single membrane. GO:0140523 GTPase-dependent fusogenic activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140523 membrane fusion GTPase activity A GTPase activity that mediates the joining two lipid bilayers to form a single membrane. GO:0140526 double membrane vesicle viral factory assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140526 A process that results in the assembly of a cytoplasmic viral factory consisting of a double-membrane bound vesicle. GO:0140525 antipodal site biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140525 antipodal zone The pole of the kinetoplast associated with kinetoplast DNA replication. The antipodal sites flank the kinetoplast DNA disk and are positioned approximately 180 degrees apart. In Trypanosoma brucei and Crithidia fasciculata, minicircles are attached at antipodal sites and they contain enzymes that catalyse some of the later reactions in minicircle replication. GO:0140528 bilobe structure assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140528 bilobe structure formation|kinetoplastid flagellar hook complex assembly|bilobe structure biogenesis The assembly and organization of a bilobe structure, a cytoskeletal structure in some kinetoplastid species linking the structures of the ciliary pocket collar and the flagellum attachment zone (aka cilium attachment zone). GO:0140527 reciprocal homologous recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140527 A DNA recombination process that results in the bidirectional exchange of genetic material between highly homologous DNA molecules. GO:0017097 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0017097 GO:0017096 acetylserotonin O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017096 MetaCyc:ACETYLSEROTONIN-O-METHYLTRANSFERASE-RXN|RHEA:15573|EC:2.1.1.4 S-adenosyl-L-methionine:N-acetylserotonin O-methyltransferase activity|acetylserotonin methyltransferase activity|N-acetylserotonin O-methyltransferase activity|hydroxyindole methyltransferase activity|hydroxyindole O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + N-acetylserotonin = S-adenosyl-L-homocysteine + melatonin. Melatonin is also known as N-acetyl-5-methoxytryptamine. GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017099 EC:1.3.99.-|RHEA:35351|Reactome:R-HSA-548831 very long-chain-acyl-CoA dehydrogenase activity Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor, where the acyl group is a very long chain fatty acid residue. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22. GO:0017098 sulfonylurea receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017098 sulphonylurea receptor binding|sulfonylurea receptor ligand Interacting selectively and non-covalently with the sulfonylurea receptor, a regulatory subunit of the ATP-sensitive potassium ion channel. OBO:GOCHE_24527 substance with herbicide role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_24527 GO:0140511 mitotic nuclear bridge stalk biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140511 Either of the regions of a mitotic nuclear bridge proximal to the main portion of each daughter nucleus. The nuclear envelope in the stalk regions is depleted of nuclear pore complexes. GO:0140510 mitotic nuclear bridge biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140510 nuclear bridge A narrow constricted region of the nucleus that forms around the anaphase spindle during closed mitosis, and connects the main portions of the newly forming daughter nuclei. GO:0140513 nuclear protein-containing complex biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0140513 nuclear complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together in the nucleus. GO:0140512 mitotic nuclear bridge midzone biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140512 The central region of a mitotic nuclear bridge, distal to the main portions of the daughter nuclei. The midzone forms a bulge that is enriched in nuclear pores that lack baskets. GO:0140515 mitotic nuclear bridge organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140515 A mitotic cell cycle process which results in the assembly, arrangement, or disassembly of the mitotic nuclear bridge during closed mitosis. GO:0140517 protein-RNA adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140517 The binding activity of a protein that brings together another protein and an RNA, permitting those molecules to function in a coordinated way. GO:0140516 mitotic nuclear pore complex disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140516 nuclear pore complex disassembly during mitosis The mitotic cell cycle process in which the controlled breakdown of the nuclear pores occurs during open or closed mitosis. GO:0017082 obsolete mineralocorticoid receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017082 aldosterone receptor OBSOLETE. Combining with a mineralocorticoid and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II. PR:000021999 death receptor biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000021999 A protein that contains multiple TNFR/NGFR cysteine-rich region (Pfam:PF00020) within the extracellular ligand-binding domain, a type I (single pass) transmembrane domain, and a cytoplasmic Death domain (Pfam:PF00531) required for intracellular signaling. GO:0017081 chloride channel regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017081 Reactome:R-HSA-383190 Modulates the activity of a chloride channel. PR:000021998 neurotrophin biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000021998 A protein that is a neurotrophic polypeptide factor that regulates neuronal differentiation and is essential for neuronal survival, neurite growth and plasticity. It contains a signal peptide, a propeptide, and a C-terminal Nerve growth factor family (Pfam:PF00243) domain. GO:0017084 delta1-pyrroline-5-carboxylate synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017084 Reactome:R-HSA-508040|RHEA:33207 D1-pyrroline-5-carboxylate synthetase activity Catalysis of the reaction: L-glutamate + ATP + NADPH = ADP + L-glutamate gamma-semialdehyde + NADP+ + phosphate. GO:0017083 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017083 EC:2.4.1.152|MetaCyc:GALACTOSIDE-3-FUCOSYLTRANSFERASE-RXN|RHEA:14257 plasma alpha-3-fucosyltransferase activity|GDP-L-fucose:1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-L-fucosyltransferase activity|galactoside 3-L-fucosyltransferase activity|Lewis-negative alpha-3-fucosyltransferase activity|GDP-beta-L-fucose:1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-alpha-L-fucosyltransferase activity|lewis-negative alpha-3-fucosyltransferase activity|galactoside 3-fucosyltransferase activity|guanosine diphosphofucose-glucoside alpha1->3-fucosyltransferase activity|GDP-beta-L-fucose:1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-L-fucosyltransferase activity|guanosine diphosphofucose-glucoside alpha-1->3-fucosyltransferase activity Catalysis of the reaction: GDP-beta-L-fucose + beta-D-galactosyl-(1,4)-N-acetyl-D-glucosaminyl-R = GDP + 1,4-beta-D-galactosyl-(1,4)-[alpha-L-fucosyl-(1,3)]-N-acetyl-D-glucosaminyl-R. GO:0017080 sodium channel regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017080 Modulates the activity of a sodium channel. GO:0017079 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0017079 GO:0017078 obsolete Hsc70 protein regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017078 Hsc70 interacting protein|Hsc70 protein regulator activity OBSOLETE. Binds to and modulates the activity of the molecular chaperone Hsc70. GO:0017075 syntaxin-1 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017075 Interacting selectively and non-covalently with the SNAP receptor syntaxin-1. GO:0017074 obsolete procollagen N-endopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017074 procollagen aminoterminal protease activity|procollagen aminopeptidase activity|type I/II procollagen N-proteinase activity|procollagen N-terminal proteinase activity|aminoterminal procollagen peptidase activity|type III procollagen|procollagen N-proteinase activity|aminoprocollagen peptidase activity|procollagen N-endopeptidase activity|procollagen N-terminal peptidase activity OBSOLETE. Catalysis of the cleavage of the N-propeptide of collagen chain alpha-1(I) at Pro-Gln and of alpha-1(II) and alpha-2(I) chains at Ala-Gln. GO:0017077 oxidative phosphorylation uncoupler activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017077 mitochondrial uncoupling protein activity|uncoupling protein activity Enables the transfer of protons from mitochondrial intermembrane space into mitochondrial matrix, dissipating the proton gradient across the mitochondrial inner membrane established by the electron transport chain during the oxidative phosphorylation (proton leak). Proton leak uncouples the processes of electron transport/proton generation and ATP synthesis. GO:0017076 purine nucleotide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017076 Interacting selectively and non-covalently with purine nucleotides, any compound consisting of a purine nucleoside esterified with (ortho)phosphate. GO:0017093 obsolete sterol regulatory element-binding protein protease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017093 SREBP protease activity|sterol regulatory element-binding protein protease activity OBSOLETE. Catalysis of the hydrolysis of peptide bonds within a sterol regulatory element binding protein (SREBP). SREBPs are transcription factors that bind sterol regulatory elements (SREs), DNA motifs found in the promoters of target genes. GO:0017092 obsolete sterol regulatory element-binding protein site 2 protease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017092 sterol regulatory element-binding protein site 2 protease activity|SREBP site 2 protease activity OBSOLETE. Catalysis of the cleavage, within the membrane-spanning helix, of the amino-terminal half (the intermediate form) of sterol regulatory element binding protein (SREBP). This activity releases the transcription factor domain of SREBP from the membrane, freeing it to enter the nucleus. GO:0017095 heparan sulfate 6-O-sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017095 EC:2.8.2.-|Reactome:R-HSA-2076419 heparin 6-O-sulfotransferase activity|heparan sulphate 6-O-sulphotransferase activity Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + heparan sulfate 6-O-sulfate; results in 6-O-sulfation of glucosamine residues in heparan sulfate. GO:0017094 obsolete sterol regulatory element-binding protein site 1 protease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017094 sterol regulatory element-binding protein site 1 protease activity|SREBP site 1 protease activity OBSOLETE. Catalysis of the cleavage of a Leu-Ser bond within the luminal loop of a sterol regulatory element binding protein (SREBP). This activity is the first of two sequential cleavage reactions and cleaves SREBP into two membrane-bound halves. GO:0017091 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0017091 GO:0017090 meprin A complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0017090 PABA peptide hydrolase complex A protein complex that is located in the cell membrane, and is involved in the metabolism of peptides, including neuropeptides. The complex has metalloendopeptidase activity that catalyzes the hydrolysis of protein and peptide substrates, preferentially on carboxyl side of hydrophobic residues. GO:0017089 glycolipid transfer activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017089 Reactome:R-HSA-9697077|Reactome:R-HSA-5340320 glycolipid transporter activity|intermembrane glycolipid transporter activity|glycolipid carrier activity|intermembrane glycolipid transfer activity Removes a glycolipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. A glycolipid is a compound usually containing 1-4 linked monosaccharide residues joined by a glycosyl linkage to a lipid. GO:0017086 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0017086 BCADH|branched-chain alpha-ketoacid dehydrogenase complex A protein complex that catalyzes the reaction 3-methyl-2-oxobutanoate + lipoamide = S-(2-methylpropanoyl)-dihydrolipoamide + carbon dioxide (CO2). This requires thiamine diphosphate; the enzyme also acts on (S)-3-methyl-2-oxopentanoate and 4-methyl-2-oxo-pentanoate. GO:0017085 response to insecticide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017085 insecticide susceptibility/resistance|insecticide resistance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insecticide stimulus. Insecticides are chemicals used to kill insects. GO:0017088 obsolete X-Pro dipeptidyl-peptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017088 X-prolyl dipeptidyl aminopeptidase activity|X-prolyl dipeptidyl peptidase activity|PepX|Xaa-Pro dipeptidyl-peptidase activity|X-Pro dipeptidyl-peptidase activity OBSOLETE. Catalysis of the hydrolysis of the terminal bond of Xaa-Pro-Xaa motifs to release unblocked, N-terminal dipeptides from substrates including Ala-Pro-para-nitroanilide and (sequentially, at the second, fourth and sixth bonds) of the motif Tyr-Pro-Phe-Pro-Gly-Pro-Ile. GO:0017087 mitochondrial processing peptidase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0017087 A protein complex consisting of a regulatory subunit (alpha-MPP) and a catalytic subunit (beta-MPP) that catalyzes the release of N-terminal targeting peptides from precursor proteins imported into the mitochondrion. GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017060 MetaCyc:2.4.1.65-RXN|Reactome:R-HSA-9603986|Reactome:R-HSA-5693925|RHEA:23628|EC:2.4.1.65 alpha-(1,4)-L-fucosyltransferase activity|beta-acetylglucosaminylsaccharide fucosyltransferase activity|blood group Lewis alpha-4-fucosyltransferase activity|Lewis blood group alpha-(1,3/4)-fucosyltransferase activity|Lewis FT activity|alpha-(1,3/1,4) fucosyltransferase III activity|alpha-4-L-fucosyltransferase activity|(Lea)-dependent (alpha-3/4)-fucosyltransferase activity|blood-group substance Lea-dependent fucosyltransferase|galactoside 3(4)-L-fucosyltransferase activity|Lewis(Le) blood group gene-dependent alpha-(1,3/4)-L-fucosyltransferase activity|alpha-(1->4)-L-fucosyltransferase activity|FucT-II activity|3-alpha-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity|guanosine diphosphofucose-beta-acetylglucosaminylsaccharide 4-alpha-L-fucosyltransferase activity|Lewis blood group alpha-(1->3/4)-fucosyltransferase activity|guanosine diphosphofucose-glycoprotein 4-alpha-fucosyltransferase activity|guanosine diphosphofucose-glycoprotein 4-alpha-L-fucosyltransferase activity|alpha(1,4)-L-fucosyltransferase activity|GDP-L-fucose:3-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 4I-alpha-L-fucosyltransferase activity|(Le(a))-dependent (alpha-3/4)-fucosyltransferase activity|blood-group substance Le(a)-dependent fucosyltransferase activity|Lewis alpha-(1->3/4)-fucosyltransferase activity|Lewis alpha-(1,3/4)-fucosyltransferase activity|GDP-beta-L-fucose:3-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 4I-alpha-L-fucosyltransferase activity|Lewis(Le) blood group gene-dependent alpha-(1->3/4)-L-fucosyltransferase activity Catalysis of the reaction: GDP-L-fucose + beta-D-galactosyl-(1,3)-N-acetyl-D-glucosaminyl-R = GDP + beta-D-galactosyl-(1,3)-[alpha-L-fucosyl-(1,4)]-N-acetyl-D-glucosaminyl-R. GO:0017062 respiratory chain complex III assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017062 complex III biogenesis|cytochrome bc(1) complex biogenesis|coenzyme Q and cytochrome c reductase complex assembly|coenzyme Q and cytochrome c reductase complex biogenesis|cytochrome bc(1) complex assembly|complex III assembly The aggregation, arrangement and bonding together of a set of components to form the cytochrome bc(1) complex, a transmembrane lipoprotein complex that it catalyzes the reduction of cytochrome c by accepting reducing equivalents from Coenzyme Q, by the aggregation, arrangement and bonding together of its constituents. GO:0017061 S-methyl-5-thioadenosine phosphorylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017061 MetaCyc:5-METHYLTHIOADENOSINE-PHOSPHORYLASE-RXN|EC:2.4.2.28|RHEA:11852|Reactome:R-HSA-1237160 methylthioadenosine phosphorylase activity|5'-methylthioadenosine:phosphate methylthio-D-ribosyl-transferase activity|methylthioadenosine nucleoside phosphorylase activity|MTA phosphorylase activity|S-methyl-5-thioadenosine:phosphate S-methyl-5-thio-alpha-D-ribosyl-transferase activity|MeSAdo/Ado phosphorylase activity|MeSAdo phosphorylase activity|MTAPase activity|5'-deoxy-5'-methylthioadenosine phosphorylase activity|5'-methylthioadenosine phosphorylase activity Catalysis of the reaction: 5'-methylthioadenosine + phosphate = adenine + 5-methylthio-D-ribose 1-phosphate. GO:0032699 negative regulation of interleukin-16 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032699 inhibition of interleukin-16 production|negative regulation of interleukin-16 biosynthetic process|negative regulation of IL-16 production|down regulation of interleukin-16 production|downregulation of interleukin-16 production|down-regulation of interleukin-16 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-16 production. GO:0032690 negative regulation of interleukin-1 alpha production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032690 negative regulation of interleukin-1 alpha secretion|down-regulation of interleukin-1 alpha production|negative regulation of interleukin-1 alpha biosynthetic process|downregulation of interleukin-1 alpha production|down regulation of interleukin-1 alpha production|inhibition of interleukin-1 alpha production|negative regulation of IL-1 alpha production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 alpha production. GO:0017057 6-phosphogluconolactonase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017057 Reactome:R-HSA-71296|MetaCyc:6PGLUCONOLACT-RXN|EC:3.1.1.31|RHEA:12556|KEGG_REACTION:R02035 6-PGL|6-phospho-D-glucono-1,5-lactone lactonohydrolase activity|phosphogluconolactonase activity Catalysis of the reaction: 6-O-phosphono-D-glucono-1,5-lactone + H(2)O = 6-phospho-D-gluconate + H(+). GO:0032698 negative regulation of interleukin-15 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032698 inhibition of interleukin-15 production|negative regulation of interleukin-15 biosynthetic process|negative regulation of IL-15 production|down regulation of interleukin-15 production|downregulation of interleukin-15 production|down-regulation of interleukin-15 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-15 production. GO:0032697 negative regulation of interleukin-14 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032697 inhibition of interleukin-14 production|negative regulation of interleukin-14 biosynthetic process|negative regulation of IL-14 production|down regulation of interleukin-14 production|downregulation of interleukin-14 production|down-regulation of interleukin-14 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-14 production. GO:0017056 structural constituent of nuclear pore biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017056 Reactome:R-HSA-6783483|Reactome:R-HSA-1176059|Reactome:R-HSA-5252041|Reactome:R-HSA-5578744|Reactome:R-HSA-170796|Reactome:R-HSA-5661474|Reactome:R-HSA-192925|Reactome:R-HSA-192627 nucleocytoplasmic transporter activity|nuclear pore activity The action of a molecule that contributes to the structural integrity of the nuclear pore complex, a protein-lined channel in the nuclear envelope that allows the transfer of macromolecules. GO:0032696 negative regulation of interleukin-13 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032696 negative regulation of interleukin-13 biosynthetic process|negative regulation of IL-13 production|down regulation of interleukin-13 production|downregulation of interleukin-13 production|down-regulation of interleukin-13 production|negative regulation of interleukin-13 secretion|inhibition of interleukin-13 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-13 production. GO:0017059 serine C-palmitoyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0017059 An enzyme complex that catalyzes the transfer of a palmitoyl on to serine, forming 3-dehydro-D-sphinganine. GO:0032695 negative regulation of interleukin-12 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032695 negative regulation of IL-12 production|down regulation of interleukin-12 production|negative regulation of NKSF production|downregulation of interleukin-12 production|down-regulation of interleukin-12 production|negative regulation of interleukin-12 secretion|negative regulation of CLMF production|inhibition of interleukin-12 production|negative regulation of interleukin-12 biosynthetic process Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-12 production. GO:0017058 FH1 domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017058 Interacting selectively and non-covalently with a FH1 domain of a protein, a proline-rich domain, usually located in front of a FH2 domain. GO:0032694 negative regulation of interleukin-11 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032694 negative regulation of IL-11 production|down regulation of interleukin-11 production|downregulation of interleukin-11 production|down-regulation of interleukin-11 production|negative regulation of interleukin-11 secretion|inhibition of interleukin-11 production|negative regulation of interleukin-11 biosynthetic process Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-11 production. GO:0017053 transcription repressor complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0017053 cytoplasmic transcriptional repressor complex|nuclear transcriptional repressor complex|transcription factor inhibitor complex|transcriptional repressor complex A protein complex that possesses activity that prevents or downregulates transcription. GO:0017052 obsolete insulin-like growth factor binding protein biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0017052 insulin-like growth factor binding protein OBSOLETE. (Was not defined before being made obsolete). GO:0032693 negative regulation of interleukin-10 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032693 negative regulation of IL-10 production|down regulation of interleukin-10 production|downregulation of interleukin-10 production|down-regulation of interleukin-10 production|inhibition of interleukin-10 production|negative regulation of interleukin-10 biosynthetic process|negative regulation of interleukin-10 secretion Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-10 production. GO:0017055 negative regulation of RNA polymerase II transcription preinitiation complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017055 down-regulation of RNA polymerase II transcriptional preinitiation complex assembly|negative regulation of RNA polymerase II transcriptional preinitiation complex assembly|negative regulation of RNA polymerase II transcriptional pre-initiation complex biosynthesis|negative regulation of RNA polymerase II transcriptional pre-initiation complex assembly|downregulation of RNA polymerase II transcriptional preinitiation complex assembly|down regulation of RNA polymerase II transcriptional preinitiation complex assembly|inhibition of RNA polymerase II transcriptional preinitiation complex assembly|negative regulation of RNA polymerase II transcriptional preinitiation complex formation Any process that stops, prevents, or reduces the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly. GO:0032692 negative regulation of interleukin-1 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032692 down-regulation of interleukin-1 production|negative regulation of interleukin-1 biosynthetic process|downregulation of interleukin-1 production|down regulation of interleukin-1 production|inhibition of interleukin-1 production|negative regulation of IL-1 production|negative regulation of interleukin-1 secretion Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 production. GO:0032691 negative regulation of interleukin-1 beta production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032691 negative regulation of IL-1 beta production|down regulation of interleukin-1 beta production|downregulation of interleukin-1 beta production|down-regulation of interleukin-1 beta production|inhibition of interleukin-1 beta production|negative regulation of interleukin-1 beta secretion|negative regulation of interleukin-1 beta biosynthetic process Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 beta production. GO:0017054 negative cofactor 2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0017054 A heterodimeric protein complex that can stably associate with TATA-binding protein on promoters, thereby preventing the assembly of transcription factors TFIIA and TFIIB and leading to repression of RNA polymerase II transcription. The two subunits, NC2alpha (Drap1) and NC2beta (Dr1), dimerize through histone fold domains of the H2A/H2B type present in the amino termini. GO:0017071 intracellular cyclic nucleotide activated cation channel complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0017071 A protein complex that forms a transmembrane channel through which cations ions may pass in response to an intracellular cyclic nucleotide binding to the channel complex or one of its constituent parts. GO:0017070 U6 snRNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017070 Interacting selectively and non-covalently with the U6 small nuclear RNA (U6 snRNA). GO:0017073 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0017073 CHEBI:94442 [3-carboxy-2-(1-oxohexadecoxy)propyl]-trimethylammonium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_94442 GO:0017072 obsolete tubulin-specific chaperone activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017072 tubulin-specific chaperone activity OBSOLETE. Assists in the correct, non-covalent assembly of tubulin-containing structures in vivo, but is not a component of the assembled structures when performing its normal biological function. GO:0032689 negative regulation of interferon-gamma production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032689 inhibition of interferon-gamma production|negative regulation of interferon-gamma biosynthetic process|negative regulation of type II interferon production|down regulation of interferon-gamma production|downregulation of interferon-gamma production|negative regulation of interferon-gamma secretion|down-regulation of interferon-gamma production Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon. GO:0032688 negative regulation of interferon-beta production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032688 downregulation of interferon-beta production|negative regulation of interferon-beta secretion|down regulation of interferon-beta production|inhibition of interferon-beta production|down-regulation of interferon-beta production|negative regulation of IFN-beta production|negative regulation of interferon-beta biosynthetic process Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-beta production. GO:0032687 negative regulation of interferon-alpha production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032687 negative regulation of interferon-alpha secretion|down regulation of interferon-alpha production|downregulation of interferon-alpha production|down-regulation of interferon-alpha production|inhibition of interferon-alpha production|negative regulation of interferon-alpha biosynthetic process Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-alpha production. GO:0017068 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0017068 GO:0017067 tyrosine-ester sulfotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017067 RHEA:19977|MetaCyc:TYROSINE-ESTER-SULFOTRANSFERASE-RXN|EC:2.8.2.9|KEGG_REACTION:R04213 tyrosine-ester sulphotransferase activity|3'-phosphoadenylyl-sulfate:L-tyrosine-methyl-ester sulfotransferase activity|aryl sulfotransferase IV|L-tyrosine methyl ester sulfotransferase activity Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + L-tyrosine methyl ester = L-tyrosine methyl ester 4-sulfate + adenosine 3',5'-diphosphate + H(+). GO:0032686 negative regulation of hepatocyte growth factor production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032686 down-regulation of hepatocyte growth factor production|inhibition of hepatocyte growth factor production|negative regulation of hepatocyte growth factor biosynthetic process|down regulation of hepatocyte growth factor production|negative regulation of HGF production|downregulation of hepatocyte growth factor production|negative regulation of scatter factor production Any process that stops, prevents, or reduces the frequency, rate, or extent of hepatocyte growth factor production. GO:0032685 negative regulation of granulocyte macrophage colony-stimulating factor production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032685 down regulation of granulocyte macrophage colony-stimulating factor production|negative regulation of granulocyte macrophage colony stimulating factor production|downregulation of granulocyte macrophage colony-stimulating factor production|down-regulation of granulocyte macrophage colony-stimulating factor production|inhibition of granulocyte macrophage colony-stimulating factor production|negative regulation of granulocyte macrophage colony-stimulating factor biosynthetic process|negative regulation of GM-CSF production Any process that stops, prevents, or reduces the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production. GO:0032684 negative regulation of fractalkine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032684 down regulation of fractalkine production|inhibition of fractalkine production|negative regulation of CX3CL1 production|down-regulation of fractalkine production|negative regulation of fractalkine biosynthetic process|negative regulation of CX3CL1 biosynthesis|downregulation of fractalkine production Any process that stops, prevents, or reduces the frequency, rate, or extent of fractalkine production. GO:0017069 snRNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017069 base pairing with snRNA|small nuclear RNA binding Interacting selectively and non-covalently with a small nuclear RNA (snRNA). GO:0017064 fatty acid amide hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017064 Reactome:R-HSA-5693751|Reactome:R-HSA-5693742 Catalysis of the hydrolysis of a fatty acid amide to yield a fatty acid. GO:0032683 negative regulation of connective tissue growth factor production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032683 negative regulation of Hcs24 production|negative regulation of Fisp12 production|negative regulation of IGFBP8 production|down-regulation of connective tissue growth factor production|negative regulation of CCN2 production|negative regulation of hypertrophic chondrocyte-specific gene product 24 production|negative regulation of connective tissue growth factor biosynthetic process|downregulation of connective tissue growth factor production|down regulation of connective tissue growth factor production|negative regulation of CTGF production|inhibition of connective tissue growth factor production Any process that stops, prevents, or reduces the frequency, rate, or extent of connective tissue growth factor production. GO:0017063 obsolete phosphatidylserine-specific phospholipase A1 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017063 phosphatidylserine-specific phospholipase A1 activity OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 2-acylglycerophosphocholine + a fatty acid anion. GO:0032682 negative regulation of chemokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032682 down-regulation of chemokine production|negative regulation of chemokine biosynthetic process|downregulation of chemokine production|negative regulation of chemokine secretion|down regulation of chemokine production|inhibition of chemokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of chemokine production. GO:0017066 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0017066 GO:0032681 regulation of lymphotoxin A production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032681 regulation of lymphotoxin A biosynthetic process|regulation of TNF-beta production|regulation of tumor necrosis factor-beta production|regulation of LTA production|regulation of lymphotoxin-alpha production Any process that modulates the frequency, rate, or extent of lymphotoxin A production. GO:0032680 regulation of tumor necrosis factor production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032680 regulation of TNF production|regulation of tumor necrosis factor biosynthetic process|regulation of tumor necrosis factor secretion|regulation of tumor necrosis factor-alpha production|regulation of TNF-alpha production|regulation of cachectin production Any process that modulates the frequency, rate or extent of tumor necrosis factor production. GO:0017065 single-strand selective uracil DNA N-glycosylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017065 Reactome:R-HSA-110221 single-strand selective monofunctional uracil-DNA glycosylase activity Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases present in single-stranded DNA. GO:0140580 mitochondrion autophagosome adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140580 mitophagy receptor The binding activity of a molecule that brings together a mitochondrial membrane and an autophagosome during mitophagy. GO:0140582 adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140582 exctracellular cAMP signaling pathway A series of molecular signals initiated by cAMP binding to its receptor on the surface of the target cell, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. GO:0140581 P-type monovalent copper transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140581 RHEA:25792|EC:7.2.2.8 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cu+(in) -> ADP + phosphate + Cu+(out). CHEBI:21415 L-tyrosyl ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21415 GO:0140576 ascorbate homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140576 cellular ascorbate homeostasis Any process involved in the maintenance of an internal steady state of ascorbate at the level of a cell. GO:0140579 obsolete oxidoreductase activity, reducing metal ions biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140579 OBSOLETE. Catalysis of an oxidation-reduction in which the metal ion is reduced. GO:0140571 transmembrane ascorbate ferrireductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140571 RHEA:30403|MetaCyc:1.10.2.1-RXN|EC:7.2.1.3 ascorbate-cytochrome b5 reductase activity|L-ascorbate-cytochrome-b5 reductase activity|L-ascorbate:ferricytochrome-b5 oxidoreductase activity Oxidation of Fe(3+) to Fe(2+) on the outer side of a membrane coupled to the reduction of L-ascorbate to monodehydro-L-ascorbate radical on the inner side of a membrane. Electrons get transferred across the membrane during the reaction. GO:0140570 extraction of mislocalized protein from mitochondrial outer membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140570 extraction of mislocalized protein from outer mitochondrion membrane The removal of a mislocalized protein from the mitochondrial outer membrane. GO:0140573 histone H3-containing nucleosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140573 histone H3 containing nucleosome A complex comprised of DNA wound around a multisubunit core and associated proteins containing the histone H3, which forms the primary packing unit of DNA into higher order structures. GO:0140572 vacuole fission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140572 The division of a vacuole within a cell to form two or more separate vacuoles. GO:0140575 transmembrane monodehydroascorbate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140575 RHEA:66524|EC:7.2.1.- Oxidation of monodehydroascorbate outside of a membrane coupled to the reduction of L-ascorbate to monodehydro-L-ascorbate radical on the inner side of a membrane. Electrons get transferred across the membrane during the reaction. CHEBI:7 (+)-car-3-ene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_7 GO:0140544 septin collar organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140544 cellular bud neck septin hourglass organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising the septin collar. GO:0140543 positive regulation of piRNA transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140543 Any process that increases the frequency, rate or extent of the synthesis of piRNA. GO:0140546 defense response to symbiont biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140546 Reactions triggered in response to the presence of a symbiont that act to protect the cell or organism from damage caused by that symbiont. GO:0140545 protein disaggregase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140545 An ATP-dependent molecular chaperone activity that mediates the solubilization of ordered protein aggregates. GO:0140548 envenomation resulting in blood agglutination in other organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140548 envenomation resulting in erythrocytes agglutination in other organism|envenomation resulting in red blood cells agglutination in other organism A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with specific proteins binding to cell-surface carbohydrates and causing calcium-dependent agglutination of blood cells in the bitten organism. GO:0140547 acquisition of seed longevity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140547 The acquisition of seed longevity is the ordered series of events during seed development, that prevent embryo deterioration and ROS damage and thus contribute to seed viability over time or in response to adverse environmental conditions. These events include protective (e.g. production of glassy cytoplasm ) and repair (e.g. oxidative stress responses) processes. GO:0140549 spore inner membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140549 spore membrane The membrane surrounding the spore core (endospore core) that separates it from its external environment. GO:0140540 negative regulation melanotic encapsulation of foreign target biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140540 Any process that stops, prevents or reduces the frequency, rate or extent of melanotic encapsulation of foreign target. GO:0140542 regulation of piRNA transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140542 Any process that modulates the frequency, rate or extent of the synthesis of a piRNA. GO:0140541 piRNA transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140541 PIWI-interacting RNA transcription|Piwi-associated RNA transcription The cellular synthesis of Piwi-interacting RNA piRNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism. GO:0140533 suppression of host RNAi-mediated antiviral immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140533 suppression of host RNAi-mediated gene silencing|suppression of host RNAi-mediated antiviral immunity Any process in which a symbiont stops, prevents, or reduces the rate or extent of the host's RNAi-mediated antiviral immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:69404 pestalamide A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_69404 GO:0140532 negative regulation of osmosensory signaling MAPK cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140532 Any process that stops, prevents or reduces the frequency, rate or extent of osmosensory signaling MAPK cascade. CHEBI:69403 carbonarone A biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_69403 GO:0140535 intracellular protein-containing complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140535 A protein-containing complex located intracellularly. GO:0140534 endoplasmic reticulum protein-containing complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140534 A protein complex that is part of an endoplasmic reticulum. GO:0140537 transcription regulator activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140537 A molecular function regulator that increases the activity of a transcription regulator via direct binding and/or post-translational modification. GO:0140536 nuclear receptor corepressor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140536 nuclear corepressor activity A transcription corepressor activity that represses or decreases the transcription of specific gene sets via binding to a DNA-bound nuclear receptor, either on its own or as part of a complex. Nuclear receptor corepressors often act by altering chromatin structure and modifications. For example, one class of transcription nuclear receptor corepressors modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators. GO:0140539 regulation of melanotic encapsulation of foreign target biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140539 Any process that modulates the frequency, rate or extent of melanotic encapsulation of foreign target. GO:0140538 negative regulation of conjugation with zygote biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140538 A process that prevents a zygote from fusing an additional cell. GO:0140531 regulation of osmosensory signaling MAPK cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140531 Any process that modulates the frequency, rate or extent of osmosensory signaling MAPK cascade. GO:0140530 MCM complex loading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140530 MCM complex loading at replication origin|MCM double hexamer formation at replication origin The protein localization process in which two MCM complexes become associated with chromatin at replication origins. MCM loading begins when origin-bound ORC and Cdc6 (Cdc18 in fission yeast) recruit one MCM2-7/Cdt1 complex to the origin, includes formation of a succession of intermediate complexes and ATP hydrolysis-dependent Mcm2-7 ring closure, and ends when two MCM hexamers fully encircle DNA, and are oriented head-to-head. The double hexamer is inactive for DNA unwinding. MCM loading takes place during G1 phase, and precedes CMG complex assembly. GO:0140566 epigenetic reader biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140566 A transcription regulator that recognizes epigenetic marks such as methylated cytosines in CpG islands and modified histones, and modulates the accessibility of cis-regulatory regions to the transcription machinery. GO:0140568 extraction of mislocalized protein from membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140568 The removal of a mislocalized protein from a cellular membrane. GO:0140567 transmembrane protein dislocase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140567 RHEA:66168 transmembrane helix dislocase The activity of removing a protein from a membrane, by binding to a transmembrane helical fragment of a tail-anchored protein and releasing it from the the hydrophobic region of one or both lipid bilayers. GO:0140569 extraction of mislocalized protein from ER membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140569 The removal of a mislocalized protein from the endoplasmic reticulum (ER) membrane. GO:0140560 xylosyl alpha-1,3-xylosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140560 EC:2.4.2.62|RHEA:22820 Catalyzes the reaction: UDP-alpha-D-xylose + [protein with EGF-like domain]-3-O-(alpha-D-xylosyl-(1->3)-beta-D-glucosyl)-L-serine <=> UDP + [protein with EGF-like domain]-3-O-(alpha-D-xylosyl-(1->3)-alpha-D-xylosyl-(1->3)-beta-D-glucosyl)-L-serine. The enzyme, found in animals and insects, is involved in the biosynthesis of the alpha-D-xylosyl-(1->3)-alpha-D-xylosyl-(1->3)- beta-D-glucosyl trisaccharide on epidermal growth factor-like (EGF- like) domains. GO:0140562 EGF-domain serine xylosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140562 EC:2.4.2.63|RHEA:62016 Catalyses the reaction: UDP-alpha-D-xylose + [protein with EGF-like domain]-L-serine <=> UDP + [protein with EGF-like domain]-3-O-(beta-D-xylosyl)-L-serine. GO:0140561 EGF-domain serine glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140561 RHEA:58116|EC:2.4.1.376 Catalysis of the reaction: UDP-alpha-D-glucose + [protein with EGF-like domain]-L-serine <=> UDP + [protein with EGF-like domain]-3-O-(beta-D-glucosyl)-L-serine. GO:0140564 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0140564 GO:0140563 UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140563 EC:2.4.2.42|RHEA:56064 Catalyzes the reaction: UDP-alpha-D-xylose + [protein with EGF-like domain]-3-O-(beta-D-glucosyl)-L-serine <=> UDP + [protein with EGF-like domain]-3-O-(alpha-D-xylosyl-(1->3)-beta-D-glucosyl)-L-serine. GO:0140554 L-arginine 3-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140554 RHEA:56744 Catalyzes the reaction: 2-oxoglutarate + [protein]-L-arginine + O2 = [protein]-(3R)-3-hydroxy-L-arginine + CO2 + succinate. GO:0140550 phosphatidylinositol-4,5-bisphosphate sensor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140550 Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of phosphatidylinositol-4,5-bisphosphate. GO:0140552 TEAD-YAP complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140552 CORUM:2870 TEAD-4-YAP complex|TEAD-3-YAP complex|TEAD-2-YAP complex|TEAD-1-YAP complex|TEAD-2 multiprotein complex A transcription factor complex that is composed of the one DNA binding protein of the TEAD family and the transcriptional coactivator YAP. CHEBI:21494 N-acetoxyarylamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_21494 GO:0007639 homeostasis of number of meristem cells biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007639 Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in the meristem. GO:0007638 mechanosensory behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007638 mechanosensory behaviour|behavioural response to mechanical stimulus|behavioral response to mechanical stimulus Behavior that is dependent upon the sensation of a mechanical stimulus. GO:0007637 proboscis extension reflex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007637 proboscis extension in response to nutritional stimulus|behavioral response to nutritional stimulus, proboscis extension The extension, through direct muscle actions, of the proboscis (the trunk-like extension of the mouthparts on the adult external head) in response to a nutritional stimulus. GO:0007636 chemosensory jump behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007636 jump response to chemical stimulus|chemosensory jump behaviour The sudden, usually upward, movement off the ground or other surface through sudden muscular effort in the legs, following exposure to a chemical substance. GO:0007635 chemosensory behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007635 chemosensory behaviour|behavioural response to chemical stimulus|behavioral response to chemical stimulus Behavior that is dependent upon the sensation of chemicals. CHEBI:21498 N-acetyl-7-O-acetylneuraminic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21498 GO:0007634 optokinetic behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007634 optokinetic behaviour The behavior of an organism pertaining to movement of the eyes and of objects in the visual field, as in nystagmus. GO:0007633 pattern orientation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007633 behavioral response to pattern orientation|behavioural response to pattern orientation The actions or reactions of an individual in response to the orientation of a visual pattern. This is exemplified by some classes of insects which are able to detect and learn the orientation of a set of stripes and subsequently behaviorally discriminate between horizontal, vertical or 45 degree stripes. GO:0007632 visual behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007632 behavioral response to visual stimulus|visual behaviour|behavioural response to visual stimulus The behavior of an organism in response to a visual stimulus. GO:0007631 feeding behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007631 Wikipedia:List_of_feeding_behaviours feeding from plant phloem|injection of substance into other organism during feeding on blood of other organism|hematophagy|feeding from tissue of other organism|eating|feeding from phloem of other organism|feeding on plant sap|feeding from xylem of other organism|behavioral response to food|feeding on blood of other organism|feeding on or from other organism|feeding from vascular tissue of another organism|feeding behaviour|behavioural response to food|taking of blood meal Behavior associated with the intake of food. GO:0007630 jump response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007630 The sudden, usually upward, movement off the ground or other surface through sudden muscular effort in the legs, following exposure to an external stimulus. CHEBI:3424 carnitinium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_3424 UBERON:0006846 surface groove biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006846 groove A furrow or an incomplete tube. UBERON:0006843 root of cranial nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006843 cranial nerve root|cranial neural root The initial segment of a cranial nerve, leaving the central nervous system. UBERON:0006828 trabecula carnea of atrium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006828 The supporting bundles of muscular fibers lining the walls of the atria[MP]. UBERON:0006834 uterus or analog biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006834 uterus A subdivision of a the reproductive tract in a female organism that is the site of embryo development. UBERON:0006833 lumen of trachea biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006833 lumen of cartilaginous trachea|tracheal lumen An anatomical space that surrounded_by a trachea. GO:0007618 mating biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007618 The pairwise union of individuals for the purpose of sexual reproduction, ultimately resulting in the formation of zygotes. GO:0007617 mating behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007617 Wikipedia:Mating_behaviour mating behaviour The behavioral interactions between organisms for the purpose of mating, or sexual reproduction resulting in the formation of zygotes. GO:0007616 long-term memory biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007616 Wikipedia:Long-term_memory The memory process that deals with the storage, retrieval and modification of information a long time (typically weeks, months or years) after receiving that information. This type of memory is typically dependent on gene transcription regulated by second messenger activation. GO:0007615 anesthesia-resistant memory biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007615 The memory process that results in the formation of consolidated memory resistant to disruption of the patterned activity of the brain, without requiring protein synthesis. GO:0007614 short-term memory biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007614 Wikipedia:Short-term_memory The memory process that deals with the storage, retrieval and modification of information received a short time (up to about 30 minutes) ago. This type of memory is typically dependent on direct, transient effects of second messenger activation. GO:0007613 memory biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007613 Wikipedia:Memory The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task). GO:0007612 learning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007612 Wikipedia:Learning Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience. UBERON:0006815 areolar connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006815 loose areolar connective tissue|loose connective tissue|areolar tissue Loose connective tissue located at the outer and inner layers of organs. Examples: submucosal connective tissue, tunica adventitia of artery, papillary dermis, superficial fascia of dorsum of hand. GO:0007611 learning or memory biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007611 The acquisition and processing of information and/or the storage and retrieval of this information over time. GO:0007610 behavior biolink:BiologicalProcess go-plus goslim_flybase_ribbon|goslim_agr|gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0007610 Wikipedia:Behavior behaviour|behavioural response to stimulus|single-organism behavior|behavioral response to stimulus The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity. CHEBI:45441 N-acetyl-L-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_45441 GO:0007619 courtship behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007619 courtship behaviour The behavior of an organism for the purpose of attracting sexual partners. GO:0007629 flight behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007629 flight behaviour The response to external or internal stimuli that results in the locomotory process of flight. Flight is the self-propelled movement of an organism through the air. GO:0007628 adult walking behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007628 adult walking behaviour The behavior of an adult relating to the progression of that organism along the ground by the process of lifting and setting down each leg. GO:0007627 obsolete larval behavior (sensu Insecta) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007627 larval behavior (sensu Insecta) OBSOLETE. Behavior in a larval form of an organism, an immature organism that must undergo metamorphosis to assume adult characteristics, as seen in insects. GO:0007626 locomotory behavior biolink:BiologicalProcess go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0007626 locomotory behavioural response to stimulus|behavior via locomotion|locomotion in response to stimulus|locomotory behavioral response to stimulus|locomotory behaviour The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions. GO:0007625 grooming behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007625 grooming behaviour The specific behavior of an organism relating to grooming, cleaning and brushing to remove dirt and parasites. GO:0007624 ultradian rhythm biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007624 The specific actions or reactions of an organism that recur with a regularity more frequent than every 24 hours. GO:0007623 circadian rhythm biolink:BiologicalProcess go-plus goslim_plant|goslim_drosophila http://purl.obolibrary.org/obo/GO_0007623 Wikipedia:Circadian_rhythm circadian process|circadian response|response to circadian rhythm Any biological process in an organism that recurs with a regularity of approximately 24 hours. GO:0007622 rhythmic behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007622 rhythmic behavioural response to stimulus|rhythmic behavioral response to stimulus|rhythmic behaviour The specific behavior of an organism that recur with measured regularity. GO:0007621 negative regulation of female receptivity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007621 downregulation of female receptivity|down regulation of female receptivity|inhibition of female receptivity|down-regulation of female receptivity Any process that stops, prevents or reduces the receptiveness of a female to male advances. GO:0007620 copulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007620 The act of sexual union between male and female, involving the transfer of sperm. UBERON:0006813 nasal skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006813 skeleton of nose Structural framework that provides support to the nasal sacs and ducts. GO:0007607 obsolete taste perception biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007607 taste perception OBSOLETE. The series of events required for the chemical composition of a soluble stimulus to be received and converted to a molecular signal. GO:0007606 sensory perception of chemical stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007606 chemosensory perception The series of events required for an organism to receive a sensory chemical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. GO:0007605 sensory perception of sound biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007605 Wikipedia:Hearing_(sense) perception of sound|hearing The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound. GO:0007604 phototransduction, UV biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007604 phototransduction, ultraviolet radiation|phototransduction, UV radiation|phototransduction, ultraviolet light|UV-sensitive opsin|phototransduction, UV light The sequence of reactions within a cell required to convert absorbed photons from UV light into a molecular signal; ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 400 nanometers. GO:0007603 phototransduction, visible light biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007603 visual transduction|visual cascade The sequence of reactions within a cell required to convert absorbed photons from visible light into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm. GO:0007602 phototransduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007602 Wikipedia:Visual_phototransduction phototrophin mediated phototransduction|phototransduction, visible light, light adaptation|opsin The sequence of reactions within a cell required to convert absorbed photons into a molecular signal. GO:0007601 visual perception biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007601 Wikipedia:Visual_perception vision|sense of sight|sensory visual perception The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image. GO:0007600 sensory perception biolink:BiologicalProcess go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0007600 Wikipedia:Perception The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. CHEBI:45410 (S)-2-hydroxypropylphosphonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_45410 UBERON:0006872 handplate apical ectodermal ridge biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006872 An apical ectodermal ridge that is part of a handplate. UBERON:0006871 embryonic footplate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006871 foot disk|footplate|foot plate|distal part of hindlimb bud the distal elements of the developing limb of vertebrates that will give rise to the pes (foot) UBERON:0006877 vasculature of liver biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006877 liver vascular system|hepatic vasculature|hepatic vascular element|liver vascular element A vasculature that is part of a liver. UBERON:0006876 vasculature of organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006876 set of blood vessels of organ|organ vasculature A vasculature that is part of a organ. UBERON:0006875 embryonic handplate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006875 handplate|hand plate|distal part of forelimb bud the distal elements of the developing limb of vertebrates that will give rise to the manus (hand) GO:0007609 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007609 GO:0007608 sensory perception of smell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007608 Wikipedia:Olfaction scent perception|olfaction|smell perception|sense of smell The series of events required for an organism to receive an olfactory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Olfaction involves the detection of chemical composition of an organism's ambient medium by chemoreceptors. This is a neurological process. UBERON:0006859 swim bladder bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006859 Embryonic structure that forms from the anterior gut epithelium at the level of the second somite that then matures to form the swim bladder. UBERON:0006861 diaphysis proper biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006861 long bone diaphysis|body proper of long bone|shaft proper of long bone Subdivision of long bone which forms the part of the bone between two metaphyses. Note that the diaphysis includes the metaphyses, but the diaphysis proper excludes these. UBERON:0006860 swim bladder biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006860 gas bladder|swimbladder|fish maw|air bladder A thin membranous, sometimes alveolated sac in the dorsal portion of the abdominal cavity. Contains a varying mixture of gases, not identical to the composition of air. May be one, two or three chambered. May be connected to the gut by a tube, the ductus pneumaticus (then called physostomous) or unconnected (then called physoclistous). CHEBI:21437 Mo-molybdopterin cofactor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21437 UBERON:0006868 seminal fluid secreting gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006868 A gland that secretes a seminal fluid. UBERON:0006866 terminal part of digestive tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006866 terminal section of digestive tract|rectal part of digestive tract|rectum The distalmost portion of the digestive tract, derived from the hindgut, and terminating with the anus. UBERON:0006865 metaphysis of femur biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006865 femoral metaphysis A metaphysis that is part of a femur. UBERON:0006864 distal metaphysis of femur biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006864 A distal metaphysis that is part of a femur. UBERON:0006863 proximal metaphysis of femur biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006863 A proximal metaphysis that is part of a femur. UBERON:0006862 diaphysis of femur biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006862 femoral shaft|femoral diaphysis|shaft of femur|corpus femoris|body of femur A diaphysis that is part of a femur[Automatically generated definition]. UBERON:0006849 scapula biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006849 scapulas|scapula@fr|shoulder blade|scapulae|scapula bone|hypercoracocïdeum@fr|hypercoracocïde@fr Endochondral bone that is dorsoventrally compressed and provides attachment site for muscles of the pectoral appendage. UBERON:0006858 adrenal/interrenal gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006858 suprarenal gland - interrenal gland|adrenal - interrenal gland|adrenal gland/interrenal tissue|adrenal gland - interrenal gland This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells[GO] UBERON:0006855 muscular coat of ureter biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006855 muscularis of ureter|muscular coat of ureter|tunica muscularis (ureter)|ureteral smooth muscle layer|tunica muscularis ureteris|muscular layer of ureter A muscular coat that is part of a ureter. UBERON:0006853 renal cortex tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006853 kidney cortex tubule|cortical tubule A region of nephron tubule that is part of a cortex of kidney. GO:0017161 inositol-1,3,4-trisphosphate 4-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017161 Reactome:R-HSA-1855180|RHEA:43392 Catalysis of the reaction: D-myo-inositol 1,3,4-trisphosphate + H2O = myo-inositol 1,3-bisphosphate + phosphate. GO:0017160 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0017160 GO:0032799 low-density lipoprotein receptor particle metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032799 low-density lipoprotein receptor metabolic process|LDL receptor metabolic process|low-density lipoprotein receptor metabolism The chemical reactions and pathways involving low-density lipoprotein receptors. GO:0032798 Swi5-Sfr1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032798 Sae3-Mei5 complex|Swi5 complex A conserved DNA recombinase mediator complex that contains two Swi5 monomers and one Sfr1 monomer in Schizosaccharomyces, or orthologs thereof (e.g. Sae3p and Mei5p in Saccharomyces). GO:0042123 glucanosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042123 Catalysis of the splitting and linkage of glucan molecules, resulting in glucan chain elongation. GO:0042122 alginic acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042122 alginic acid degradation|alginic acid breakdown|alginate catabolism|alginate catabolic process|alginic acid catabolism The chemical reactions and pathways resulting in the breakdown of alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds). GO:0042125 protein galactosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042125 protein amino acid galactosylation The addition of a galactose molecule to a protein amino acid. GO:0042124 1,3-beta-glucanosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042124 Catalysis of the splitting and linkage of (1->3)-beta-D-glucan molecules, resulting in (1->3)-beta-D-glucan chain elongation. GO:0042121 alginic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042121 alginate biosynthetic process|alginate biosynthesis|alginic acid anabolism|alginic acid synthesis|alginic acid formation|alginic acid biosynthesis The chemical reactions and pathways resulting in the formation of alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds). GO:0042120 alginic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042120 alginic acid metabolism|alginate metabolism|alginate metabolic process The chemical reactions and pathways involving alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds). CHEBI:137017 1-(1Z-octadecenyl)-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137017 CHEBI:137016 1-(1Z-octadecenyl)-sn-glycero-3-phospho-(N-arachidonoyl)ethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137016 GO:0042127 regulation of cell population proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042127 regulation of cell proliferation Any process that modulates the frequency, rate or extent of cell proliferation. GO:0017159 pantetheine hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017159 KEGG_REACTION:R02973|RHEA:13445|EC:3.5.1.92|MetaCyc:3.5.1.92-RXN|Reactome:R-HSA-8938300 vanin|pantetheinase activity|(R)-pantetheine amidohydrolase activity|vanin-1 Catalysis of the reaction: (R)-pantetheine + H(2)O = (R)-pantothenate + cysteamine. GO:0042126 nitrate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042126 nitrate metabolism The chemical reactions and pathways involving nitrates, inorganic or organic salts and esters of nitric acid. GO:0042129 regulation of T cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042129 regulation of T lymphocyte proliferation|regulation of T-cell proliferation|regulation of T-lymphocyte proliferation Any process that modulates the frequency, rate or extent of T cell proliferation. GO:0042128 nitrate assimilation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042128 MetaCyc:PWY-381 assimilatory nitrate reduction The nitrogen metabolic process that encompasses the uptake of nitrate from the environment and reduction to ammonia, and results in the incorporation of nitrogen derived from nitrate into cellular substances. GO:0017156 calcium-ion regulated exocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017156 calcium ion-dependent exocytosis The release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell, induced by a rise in cytosolic calcium-ion levels. GO:0032797 SMN complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032797 SMN core complex|survival motor neuron complex A protein complex that contains the survival motor neuron (SMN) protein and at least eight additional integral components, including the Gemin2-8 and Unrip proteins; the complex is found in the cytoplasm and in nuclear Gems, and is involved in spliceosomal snRNP assembly in the cytoplasm and in pre-mRNA splicing in the nucleus. GO:0017155 obsolete sodium:hydrogen antiporter regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017155 sodium:proton antiporter regulator|sodium:hydrogen antiporter regulator activity OBSOLETE. This term was not defined before being made obsolete. GO:0032796 uropod organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032796 uropod organisation|uropod organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a uropod, a rigid membrane projection with related cytoskeletal components at the trailing edge of a lymphocyte or other cell in the process of migrating or being activated. CHEBI:137010 1-(1Z-octadecenyl)-sn-glycero-3-phospho-(N-oleoyl)ethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137010 GO:0017158 regulation of calcium ion-dependent exocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017158 Any process that modulates the frequency, rate or extent of calcium ion-dependent exocytosis. GO:0032795 heterotrimeric G-protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032795 Interacting selectively and non-covalently with a heterotrimeric G-protein. GO:0017157 regulation of exocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017157 Any process that modulates the frequency, rate or extent of exocytosis. GO:0032794 GTPase activating protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032794 GAP binding Interacting selectively and non-covalently with a GTPase activating protein. CHEBI:137015 3-dehydro-scyllo-inosose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137015 GO:0017152 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0017152 GO:0032793 positive regulation of CREB transcription factor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032793 activation of CREB transcription factor|CREB activator|activation of CREB Any process that activates or increases the frequency, rate or extent of activity of the transcription factor CREB. GO:0017151 DEAD/H-box RNA helicase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017151 Interacting selectively and non-covalently with the enzyme DEAD/H-box RNA helicase. GO:0032792 negative regulation of CREB transcription factor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032792 inhibition of CREB transcription factor|CREB inhibitor Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor CREB. GO:0032791 lead ion binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032791 Interacting selectively and non-covalently with lead (Pb) ions. GO:0017154 semaphorin receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017154 Combining with a semaphorin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0017153 sodium:dicarboxylate symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017153 sodium:dicarboxylate cotransporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in). GO:0032790 ribosome disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032790 ribosome dissociation factor|ribosome recycling The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits. GO:0017170 obsolete KU70 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017170 KU70 binding OBSOLETE. Interacting selectively and non-covalently with Ku70, a protein involved in non-homologous DNA end joining. GO:0017172 cysteine dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017172 MetaCyc:CYSTEINE-DIOXYGENASE-RXN|EC:1.13.11.20|Reactome:R-HSA-1614645|KEGG_REACTION:R00893|RHEA:20441 Catalysis of the reaction: L-cysteine + O(2) = 3-sulfino-L-alanine + H(+). GO:0017171 serine hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017171 Catalysis of the hydrolysis of a substrate by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine). GO:0032789 unsaturated monocarboxylic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032789 unsaturated monocarboxylic acid metabolism|unsaturated monocarboxylate metabolic process The chemical reactions and pathways involving unsaturated monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-) and one or more unsaturated C-C bonds. GO:0032788 saturated monocarboxylic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032788 saturated monocarboxylic acid metabolism|saturated monocarboxylate metabolic process The chemical reactions and pathways involving saturated monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-) and fully saturated C-C bonds. GO:0032787 monocarboxylic acid metabolic process biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0032787 monocarboxylic acid metabolism|monocarboxylate metabolic process The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-). GO:0042134 rRNA primary transcript binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042134 pre-rRNA binding Interacting selectively and non-covalently with an unprocessed ribosomal RNA transcript. GO:0042133 neurotransmitter metabolic process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0042133 neurotransmitter metabolism The chemical reactions and pathways involving neurotransmitters, any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. GO:0042136 neurotransmitter biosynthetic process biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0042136 neurotransmitter biosynthesis|neurotransmitter anabolism|neurotransmitter synthesis|neurotransmitter formation|neurotransmitter biosynthetic process and storage|neurotransmitter biosynthesis and storage The chemical reactions and pathways resulting in the formation of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. GO:0042135 neurotransmitter catabolic process biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0042135 neurotransmitter breakdown|neurotransmitter degradation|neurotransmitter catabolism The chemical reactions and pathways resulting in the breakdown of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. GO:0042130 negative regulation of T cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042130 negative regulation of T lymphocyte proliferation|downregulation of T cell proliferation|down regulation of T cell proliferation|inhibition of T cell proliferation|negative regulation of T-cell proliferation|negative regulation of T-lymphocyte proliferation|down-regulation of T cell proliferation Any process that stops, prevents or reduces the rate or extent of T cell proliferation. GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042132 EC:3.1.3.11|RHEA:11064|Reactome:R-HSA-70479|MetaCyc:F16BDEPHOS-RXN fructose bisphosphate phosphatase activity|D-fructose-1,6-bisphosphate 1-phosphohydrolase activity|fructose-1,6-bisphosphatase activity|hexose bisphosphatase activity|fructose 1,6-diphosphate phosphatase activity|fructose 1,6-diphosphatase activity|FBPase activity|D-fructose 1,6-diphosphatase activity|hexosediphosphatase activity|fructose 1,6-bisphosphate phosphatase activity|fructose 1,6-bisphosphatase activity|fructose-bisphosphatase activity|fructose diphosphate phosphatase activity|D-fructose-1,6-bisphosphate phosphatase activity|hexose diphosphatase activity|fructose diphosphatase activity Catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. GO:0042131 thiamine phosphate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042131 thiamin monophosphate phosphatase|thiamin phosphate phosphatase activity|ThMPase Catalysis of the reaction: thiamine phosphate + H2O = thiamine + phosphate. CHEBI:137029 N,N-dihydroxy-L-tetrahomomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137029 CHEBI:137028 N,N-dihydroxy-L-trihomomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137028 CHEBI:137027 N,N-dihydroxy-L-dihomomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137027 GO:0042138 meiotic DNA double-strand break formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042138 The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I. This results in the initiation of meiotic recombination. GO:0042137 sequestering of neurotransmitter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042137 neurotransmitter retention|sequestration of neurotransmitter|neurotransmitter storage|neurotransmitter sequestration|neurotransmitter biosynthesis and storage|neurotransmitter biosynthetic process and storage|retention of neurotransmitter|storage of neurotransmitter The process of binding or confining a neurotransmitter such that it is separated from other components of a biological system. GO:0042139 early meiotic recombination nodule assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042139 During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form small, electron dense structures in association with meiotic chromosomes during leptotene and zygotene. CHEBI:137022 N-hydroxy-L-dihomomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137022 GO:0032786 positive regulation of DNA-templated transcription, elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032786 positive regulation of DNA-dependent transcription, elongation|positive regulation of transcription elongation, DNA-dependent|upregulation of RNA elongation|positive regulation of transcription elongation|up-regulation of RNA elongation|positive regulation of transcriptional elongation|stimulation of RNA elongation|activation of RNA elongation|positive transcription elongation regulator activity|up regulation of RNA elongation Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase. GO:0017167 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0017167 CHEBI:137021 5(S),6(S)-epoxy-18(S)-hydroxy-(7E,9E,11Z,14Z,16E)-icosapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137021 GO:0032785 negative regulation of DNA-templated transcription, elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032785 downregulation of RNA elongation|down regulation of RNA elongation|negative regulation of transcription elongation|negative regulation of DNA-dependent transcription, elongation|negative regulation of transcription elongation, DNA-dependent|inhibition of RNA elongation|negative regulation of transcriptional elongation|down-regulation of RNA elongation|negative transcription elongation regulator activity Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase. UBERON:5102389 manual digit digitopodial skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_5102389 manual digit|manual digit skeleton A subdivision of the skeleton of the autopod consisting of the phalanges of manual digit plus the associated metapodial element. GO:0017166 vinculin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017166 Interacting selectively and non-covalently with vinculin, a protein found in muscle, fibroblasts, and epithelial cells that binds actin and appears to mediate attachment of actin filaments to integral proteins of the plasma membrane. GO:0032784 regulation of DNA-templated transcription, elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032784 regulation of RNA elongation|transcription elongation regulator activity|regulation of transcriptional elongation|regulation of DNA-dependent transcription, elongation|regulation of transcription elongation, DNA-dependent Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase. GO:0017169 CDP-alcohol phosphatidyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017169 Catalysis of the reaction: CDP + alcohol = CMP + phosphatidyl alcohol. GO:0017168 5-oxoprolinase (ATP-hydrolyzing) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017168 MetaCyc:5-OXOPROLINASE-ATP-HYDROLYSING-RXN|Wikipedia:5-oxoprolinase_(ATP-hydrolysing)|RHEA:10348|EC:3.5.2.9|KEGG_REACTION:R00251|Reactome:R-HSA-5603208|Reactome:R-HSA-1247935 5-oxo-L-prolinase activity|L-pyroglutamate hydrolase activity|pyroglutamate hydrolase activity|pyroglutamase (ATP-hydrolyzing) activity|5-oxoprolinase (ATP-hydrolysing)|5-OPase activity|pyroglutamase (ATP-hydrolysing)|pyroglutamase activity|5-oxoprolinase activity|pyroglutamic hydrolase activity|oxoprolinase activity|5-oxo-L-proline amidohydrolase (ATP-hydrolysing) Catalysis of the reaction: 5-oxo-L-proline + ATP + 2 H(2)O = L-glutamate + ADP + 2 H(+) + phosphate. GO:0032783 super elongation complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032783 ELL-EAF complex|ELL-EAF-EBP complex A transcription elongation factor complex that increases the overall rate of RNA polymerase II transcription elongation by suppressing transient polymerase pausing. At minimum, the complex contains a transcription factor of the ELL family, an EAF protein, and an AFF family protein or distant relative and most likely also P-TEFb and AF9 or ENL. The complex is conserved from yeast to humans. In Schizosaccharomyces pombe it contains Ell1, Eaf1, and Ebp1, but it is absent from S. cerevisiae. CHEBI:137026 N-hydroxy-L-hexahomomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137026 GO:0032782 bile acid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032782 The regulated release of bile acid, composed of any of a group of steroid carboxylic acids occurring in bile, by a cell or a tissue. GO:0017163 obsolete basal transcription repressor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017163 basal transcription repressor activity OBSOLETE. Any transcription regulator activity that prevents or downregulates basal transcription. Basal transcription results from transcription that is controlled by the minimal complement of proteins necessary to reconstitute transcription from a minimal promoter. GO:0032781 positive regulation of ATPase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032781 positive regulation of adenosinetriphosphatase activity|up-regulation of ATPase activity|upregulation of ATPase activity|up regulation of ATPase activity|activation of ATPase activity|stimulation of ATPase activity Any process that activates or increases the rate of ATP hydrolysis by an ATPase. CHEBI:70399 meleagrine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70399 GO:0017162 aryl hydrocarbon receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017162 Interacting selectively and non-covalently with an aryl hydrocarbon receptor. CHEBI:137025 N-hydroxy-L-pentahomomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137025 GO:0032780 negative regulation of ATPase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032780 inhibition of ATPase activity|down regulation of ATPase activity|downregulation of ATPase activity|negative regulation of adenosinetriphosphatase activity|down-regulation of ATPase activity Any process that stops or reduces the rate of ATP hydrolysis by an ATPase. GO:0017165 obsolete dipeptidase E activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017165 peptidase E activity|PepE gene product (Salmonella typhimurium) activity|aspartyl dipeptidase activity|dipeptidase E activity|alpha-aspartyl dipeptidase activity OBSOLETE. Catalysis of the hydrolysis of dipeptides Asp-Xaa; does not act on peptides with N-terminal Glu, Asn or Gln, nor does it cleave isoaspartyl peptides. CHEBI:137024 N-hydroxy-L-tetrahomomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137024 GO:0017164 obsolete nicotinic acetylcholine receptor-associated protein activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017164 nicotinic acetylcholine receptor-associated protein activity OBSOLETE. (Was not defined before being made obsolete). CHEBI:137023 N-hydroxy-L-trihomomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137023 GO:0032779 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032779 GO:0032778 P-type cobalt transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032778 RHEA:32779 cobalt-transporting ATPase activity|cobalt transporting ATPase activity|ATP-dependent cobalt transmembrane transporter activity|ATPase-coupled cobalt transmembrane transporter activity|cobalt porter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cobalt(out) = ADP + phosphate + cobalt(in). GO:0032777 Piccolo NuA4 histone acetyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032777 A heterotrimeric H4/H2A histone acetyltransferase complex with a substrate preference of chromatin over free histones. It contains a subset of the proteins found in the larger NuA4 histone acetyltransferase complex; for example, the S. cerevisiae complex contains Esa1p, Yng2p, and Epl1p. GO:0032776 DNA methylation on cytosine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032776 cytosine methylation The covalent transfer of a methyl group to C-5 or N-4 of cytosine in a DNA molecule. GO:0042145 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042145 GO:0042144 vacuole fusion, non-autophagic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042144 vacuole fusion (non-autophagic)|homotypic vacuole fusion (non-autophagic)|homotypic vacuole fusion|homotypic vacuole fusion, non-autophagic The fusion of two vacuole membranes to form a single vacuole. GO:0042147 retrograde transport, endosome to Golgi biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042147 retrograde (endosome to Golgi) transport The directed movement of membrane-bounded vesicles from endosomes back to the trans-Golgi network where they are recycled for further rounds of transport. GO:0042146 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042146 GO:0042141 obsolete mating pheromone exporter biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042141 mating pheromone exporter OBSOLETE. Exports diffusible peptide signals that are responsible for binding to other cells and triggering a series of responses to facilitate mating. GO:0042140 late meiotic recombination nodule assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042140 During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form small, electron dense structures in association with meiotic chromosomes during pachytene. Involved in the catalysis crossing over. GO:0042143 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042143 GO:0042142 obsolete heavy metal chelation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042142 heavy metal chelation OBSOLETE. The strong but reversible binding of a heavy metal ion by a larger molecule such as protein. GO:0042149 cellular response to glucose starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042149 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of glucose. GO:0017138 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0017138 GO:0042148 strand invasion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042148 Rad51-mediated strand invasion|D-loop biosynthesis|D-loop formation|displacement loop biosynthesis|displacement loop formation The process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules. GO:0017137 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0017137 GO:0017139 obsolete arsenate sensitivity/resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017139 arsenate sensitivity/resistance OBSOLETE. (Was not defined before being made obsolete). GO:0032775 DNA methylation on adenine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032775 adenine methylation The covalent transfer of a methyl group to N-6 of adenine in a DNA molecule. GO:0017134 fibroblast growth factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017134 FGF binding|FGF 6 binding|FGF 5 binding|fibroblast growth factor 6 binding|fibroblast growth factor 5 binding|FGF 4 binding|FGF 3 binding|fibroblast growth factor 4 binding|fibroblast growth factor 3 binding|FGF 2 binding|FGF 1 binding|fibroblast growth factor 2 binding|fibroblast growth factor 1 binding Interacting selectively and non-covalently with a fibroblast growth factor. GO:0032774 RNA biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032774 RNA biosynthesis|RNA anabolism|RNA synthesis|RNA formation The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication. GO:0017133 mitochondrial electron transfer flavoprotein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0017133 A protein complex located in the mitochondrion. It contains flavin adenine dinucleotide (FAD) that, together with an acyl-CoA dehydrogenase, forms a system that oxidizes an acyl-CoA molecule and reduces ubiquinone and other acceptors in the mitochondrial electron transport system. GO:0017136 NAD-dependent histone deacetylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017136 SIR2 Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from a histone. GO:0032773 positive regulation of monophenol monooxygenase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032773 up regulation of monophenol oxygenase activity|activation of monophenol oxygenase activity|stimulation of monophenol oxygenase activity|up-regulation of monophenol oxygenase activity|positive regulation of monophenol oxygenase activity|upregulation of monophenol oxygenase activity Any process that activates or increases the activity of the enzyme monophenol oxygenase. Monophenol monooxygenase catalyzes the reaction: L-tyrosine + L-DOPA + O2 = L-DOPA + DOPAquinone + H2O. GO:0017135 obsolete membrane-associated protein with guanylate kinase activity interacting biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017135 membrane-associated protein with guanylate kinase activity interacting OBSOLETE. The interaction with synapse-associated membrane-associated protein with guanylate kinase activity. GO:0032772 negative regulation of monophenol monooxygenase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032772 down regulation of monophenol oxygenase activity|downregulation of monophenol oxygenase activity|down-regulation of monophenol oxygenase activity|inhibition of monophenol oxygenase activity|negative regulation of monophenol oxygenase activity Any process that stops or reduces the activity of the enzyme monophenol monooxygenase. Monophenol monooxygenase catalyzes the reaction: L-tyrosine + L-DOPA + O2 = L-DOPA + DOPAquinone + H2O. GO:0032771 regulation of monophenol monooxygenase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032771 regulation of monophenol oxygenase activity Any process that modulates the activity of the enzyme monophenol monooxygenase. Monophenol monooxygenase catalyzes the reaction: L-tyrosine + L-DOPA + O2 = L-DOPA + DOPAquinone + H2O. GO:0017130 poly(C) RNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017130 poly(rC) binding|poly(C) binding Interacting selectively and non-covalently with a sequence of cytosine residues in an RNA molecule. GO:0032770 positive regulation of monooxygenase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032770 stimulation of monooxygenase activity|up-regulation of monooxygenase activity|activation of monooxygenase activity|up regulation of monooxygenase activity|upregulation of monooxygenase activity Any process that activates or increases the activity of a monooxygenase. GO:0017132 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0017132 GO:0017131 uridine-rich cytoplasmic polyadenylylation element binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017131 U-rich CPE binding|uridine-rich cytoplasmic polyadenylation element binding Interacting selectively and non-covalently with U-rich sequence in the 3'-end of nuclear-transcribed mRNAs; required for cytoplasmic polyadenylylation. GO:0042150 plasmid recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042150 A process of DNA recombination occurring within a plasmid or between plasmids and other plasmids or DNA molecules. CHEBI:45394 TMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_45394 GO:0017150 tRNA dihydrouridine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017150 Reactome:R-HSA-6782296|RHEA:23624|MetaCyc:RXN0-1281 Catalysis of the reaction: tRNA-uracil + acceptor = tRNA-dihydrouridine + reduced acceptor. GO:0032769 negative regulation of monooxygenase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032769 down-regulation of monooxygenase activity|downregulation of monooxygenase activity|down regulation of monooxygenase activity|inhibition of monooxygenase activity Any process that stops or reduces the activity of a monooxygenase. GO:0032768 regulation of monooxygenase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032768 Any process that modulates the activity of a monooxygenase. GO:0032767 copper-dependent protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032767 Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in the presence of copper. GO:0032766 NHE3/E3KARP/ACTN4 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032766 NHE3/E3KARP/alpha-actinin complex A heterotrimeric protein complex formed by the association of NHE3, E3KARP and alpha-actinin upon an increase in calcium ion concentration; found in clusters localized on plasma membrane and in intracellular compartments. GO:0032765 positive regulation of mast cell cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032765 up-regulation of mast cell cytokine production|upregulation of mast cell cytokine production|up regulation of mast cell cytokine production|activation of mast cell cytokine production|stimulation of mast cell cytokine production Any process that activates or increases the frequency, rate, or extent of mast cell cytokine production. GO:0042156 obsolete zinc-mediated transcriptional activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042156 zinc-mediated transcriptional activator activity OBSOLETE. Initiates or upregulates transcription in the presence of zinc. GO:0042155 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042155 GO:0042158 lipoprotein biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042158 lipoprotein biosynthesis|lipoprotein anabolism|lipoprotein synthesis|lipoprotein formation The chemical reactions and pathways resulting in the formation of any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids. GO:0042157 lipoprotein metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042157 lipoprotein metabolism The chemical reactions and pathways involving any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids. GO:0042152 RNA-mediated DNA recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042152 The reverse transcription of an RNA molecule followed by recombination between the resultant cDNA and its homologous chromosomal allele. OBO:chebi#is_conjugate_acid_of is conjugate acid of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of GO:0042151 nematocyst biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042151 Wikipedia:Cnidocyte cnidocyst An organelle found in cnidoblast (nematoblast) cells. When matured, these stinging organelles store toxins and can deliver them when the cnidocil (a short extension of the cnidocyst) is stimulated by a prey or another stimulus. GO:0042154 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042154 GO:0042153 obsolete RPTP-like protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042153 RPTP-like protein binding|receptor protein tyrosine phosphatase-like protein binding OBSOLETE. Interacting selectively and non-covalently with proteins with similar structure/function to receptor protein tyrosine phosphatases. CHEBI:137007 N,N-dihydroxy-L-polyhomomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137007 CHEBI:137006 N-hydroxy-L-polyhomomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137006 CHEBI:3259 CCCP biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_3259 CHEBI:137005 L-hexahomomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137005 GO:0017149 obsolete protein biosynthetic process inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017149 protein biosynthetic process inhibitor activity|protein formation inhibitor activity|protein synthesis inhibitor activity|protein anabolism inhibitor activity OBSOLETE. (Was not defined before being made obsolete). GO:0017148 negative regulation of translation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017148 downregulation of protein biosynthetic process|negative regulation of protein anabolism|down regulation of protein biosynthetic process|negative regulation of protein synthesis|inhibition of protein biosynthetic process|protein biosynthetic process inhibitor activity|protein biosynthesis inhibitor activity|negative regulation of protein formation|negative regulation of protein biosynthesis|down-regulation of protein biosynthetic process|negative regulation of protein biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA. GO:0042159 lipoprotein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042159 lipoprotein degradation|lipoprotein breakdown|lipoprotein catabolism The chemical reactions and pathways resulting in the breakdown of any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids. CHEBI:137009 1-(1Z-octadecenyl)-sn-glycero-3-phospho-(N-hexadecanoyl)ethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137009 GO:0032764 negative regulation of mast cell cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032764 inhibition of mast cell cytokine production|down regulation of mast cell cytokine production|downregulation of mast cell cytokine production|down-regulation of mast cell cytokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell cytokine production. GO:0017145 stem cell division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017145 stem cell renewal The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types. CHEBI:137000 C-terminal Xaa-Gly(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137000 GO:0017144 drug metabolic process biolink:BiologicalProcess go-plus goslim_chembl|goslim_pir http://purl.obolibrary.org/obo/GO_0017144 Wikipedia:Drug_metabolism drug metabolism The chemical reactions and pathways involving a drug, a substance used in the diagnosis, treatment or prevention of a disease; as used here antibiotic substances (see antibiotic metabolism) are considered to be drugs, even if not used in medical or veterinary practice. GO:0032763 regulation of mast cell cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032763 Any process that modulates the frequency, rate, or extent of mast cell cytokine production. GO:0017147 Wnt-protein binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0017147 Interacting selectively and non-covalently with Wnt-protein, a secreted growth factor involved in signaling. GO:0032762 mast cell cytokine production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032762 Any process that contributes to cytokine production by a mast cell. GO:0017146 NMDA selective glutamate receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0017146 N-methyl-D-aspartate selective glutamate receptor complex|NMDA-selective glutamate receptor An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. NMDA receptors are composed of assemblies of NR1 subunits (Figure 3) and NR2 subunits, which can be one of four separate gene products (NR2A-D). Expression of both subunits are required to form functional channels. The glutamate binding domain is formed at the junction of NR1 and NR2 subunits. NMDA receptors are permeable to calcium ions as well as being permeable to other ions. Thus NMDA receptor activation leads to a calcium influx into the post-synaptic cells, a signal thought to be crucial for the induction of NMDA-receptor dependent LTP and LTD. GO:0032761 positive regulation of lymphotoxin A production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032761 upregulation of lymphotoxin A production|positive regulation of LTA production|positive regulation of lymphotoxin-alpha production|stimulation of lymphotoxin A production|up-regulation of lymphotoxin A production|activation of lymphotoxin A production|positive regulation of TNF-beta production|positive regulation of tumor necrosis factor-beta production|up regulation of lymphotoxin A production|positive regulation of lymphotoxin A biosynthetic process Any process that activates or increases the frequency, rate, or extent of lymphotoxin A production. GO:0032760 positive regulation of tumor necrosis factor production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032760 positive regulation of tumor necrosis factor-alpha production|positive regulation of TNF-alpha production|stimulation of tumor necrosis factor production|up-regulation of tumor necrosis factor production|activation of tumor necrosis factor production|positive regulation of tumor necrosis factor secretion|positive regulation of cachectin secretion|positive regulation of TNF production|up regulation of tumor necrosis factor production|positive regulation of tumor necrosis factor formation|positive regulation of tumor necrosis factor biosynthetic process|positive regulation of tumor necrosis factor biosynthesis|positive regulation of TNF secretion|upregulation of tumor necrosis factor production Any process that activates or increases the frequency, rate or extent of tumor necrosis factor production. CHEBI:137004 L-pentahomomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137004 GO:0017141 obsolete antibiotic susceptibility/resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017141 antibiotic susceptibility/resistance OBSOLETE. (Was not defined before being made obsolete). CHEBI:137003 C-terminal Xaa-hydroxyglycino(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137003 GO:0017140 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0017140 GO:0017143 insecticide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017143 insecticide metabolism The chemical reactions and pathways involving insecticides, chemicals used to kill insects. CHEBI:137002 L-tetrahomomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137002 GO:0017142 obsolete toxin susceptibility/resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017142 toxin susceptibility/resistance OBSOLETE. (Was not defined before being made obsolete). CHEBI:137001 C-terminal alpha-amino-acid amide residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137001 GO:0042161 lipoprotein oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042161 The modification of a lipoprotein by oxidation of one or more amino acids or the lipid group. GO:0032759 positive regulation of TRAIL production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032759 up regulation of TRAIL production|positive regulation of TRAIL biosynthetic process|upregulation of TRAIL production|stimulation of TRAIL production|up-regulation of TRAIL production|activation of TRAIL production Any process that activates or increases the frequency, rate, or extent of TRAIL production. UBERON:0006919 tongue squamous epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006919 squamous epithelium of tongue A squamous epithelium that is part of a tongue. GO:0042160 lipoprotein modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042160 The chemical reactions and pathways resulting in the covalent alteration of one or more amino acid or lipid residues occurring in a lipoprotein, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids. GO:0032758 positive regulation of interleukin-9 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032758 positive regulation of IL-9 production|positive regulation of interleukin-9 biosynthetic process|upregulation of interleukin-9 production|stimulation of interleukin-9 production|activation of interleukin-9 production|up-regulation of interleukin-9 production|up regulation of interleukin-9 production Any process that activates or increases the frequency, rate, or extent of interleukin-9 production. GO:0032757 positive regulation of interleukin-8 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032757 positive regulation of IL-8 production|positive regulation of interleukin-8 biosynthetic process|upregulation of interleukin-8 production|stimulation of interleukin-8 production|up-regulation of interleukin-8 production|activation of interleukin-8 production|positive regulation of interleukin-8 secretion|up regulation of interleukin-8 production Any process that activates or increases the frequency, rate, or extent of interleukin-8 production. GO:0032756 positive regulation of interleukin-7 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032756 upregulation of interleukin-7 production|stimulation of interleukin-7 production|activation of interleukin-7 production|up-regulation of interleukin-7 production|positive regulation of interleukin-7 secretion|up regulation of interleukin-7 production|positive regulation of interleukin-7 biosynthetic process|positive regulation of IL-7 production Any process that activates or increases the frequency, rate, or extent of interleukin-7 production. UBERON:0006916 non-keratinized epithelium of tongue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006916 A non-keratinized stratified squamous epithelium that is part of a tongue. UBERON:0006915 stratified squamous epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006915 epithelium stratificatum squamosum Multilaminar epithelium which consists of more than one layer of squamous cells only one layer of which is in contact with a basement membrane. Examples: keratinized stratified squamous epithelium, epithelium of wall of esophagus.[FMA] GO:0032755 positive regulation of interleukin-6 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032755 upregulation of interleukin-6 production|stimulation of interleukin-6 production|up-regulation of interleukin-6 production|activation of interleukin-6 production|positive regulation of interleukin-6 secretion|up regulation of interleukin-6 production|positive regulation of IL-6 production|positive regulation of interleukin-6 biosynthetic process Any process that activates or increases the frequency, rate, or extent of interleukin-6 production. GO:0032754 positive regulation of interleukin-5 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032754 upregulation of interleukin-5 production|stimulation of interleukin-5 production|up-regulation of interleukin-5 production|activation of interleukin-5 production|positive regulation of interleukin-5 secretion|up regulation of interleukin-5 production|positive regulation of IL-5 production|positive regulation of interleukin-5 biosynthetic process Any process that activates or increases the frequency, rate, or extent of interleukin-5 production. UBERON:0006914 squamous epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006914 An epithelium characterised by its most superficial layer consisting of squamous epithelial cells. GO:0042167 heme catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042167 haem catabolic process|heme degradation|heme catabolism|heme breakdown|haem catabolism The chemical reactions and pathways resulting in the breakdown of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring. GO:0042166 acetylcholine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042166 Interacting selectively and non-covalently with acetylcholine, an acetic acid ester of the organic base choline that functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions. GO:0042169 SH2 domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042169 Interacting selectively and non-covalently with a SH2 domain (Src homology 2) of a protein, a protein domain of about 100 amino-acid residues and belonging to the alpha + beta domain class. GO:0042168 heme metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042168 haem metabolic process|heme metabolism|haem metabolism The chemical reactions and pathways involving heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring. GO:0042163 interleukin-12 beta subunit binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042163 NKSFp40 binding|IL-12B binding|CLMFp40 binding|IL-12p40 binding Interacting selectively and non-covalently with the beta subunit of interleukin-12. CHEBI:45389 (R)-styrene oxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_45389 GO:0042162 telomeric DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042162 telomeric repeat binding|telomere binding Interacting selectively and non-covalently with a telomere, a specific structure at the end of a linear chromosome required for the integrity and maintenance of the end. GO:0042165 neurotransmitter binding biolink:MolecularActivity go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0042165 Interacting selectively and non-covalently with a neurotransmitter, any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell. GO:0042164 interleukin-12 alpha subunit binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042164 IL-12A binding|CLMFp35 binding|IL-12p35 binding|NKSFp35 binding Interacting selectively and non-covalently with the alpha subunit of interleukin-12. GO:0017119 Golgi transport complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0017119 Sec34/35 complex|COG complex|conserved oligomeric Golgi complex A multisubunit tethering complex of the CATCHR family (complexes associated with tethering containing helical rods) that has a role in tethering vesicles to the Golgi prior to fusion. Composed of 8 subunits COG1-8. GO:0017116 single-stranded DNA helicase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017116 ssDNA-dependent ATP-dependent DNA helicase activity|single-stranded DNA-dependent ATPase activity|ssDNA-dependent ATPase activity|single-stranded DNA-dependent ATP-dependent DNA helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of single-stranded DNA; drives the unwinding of a DNA helix. GO:0017115 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0017115 GO:0017118 lipoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017118 RHEA:20473 Catalysis of the transfer of the lipoyl group from lipoyl-AMP to the lysine residue of lipoate-dependent enzyme. GO:0017117 single-stranded DNA-dependent ATP-dependent DNA helicase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0017117 ssDNA-dependent ATP-dependent DNA helicase complex A protein complex that possesses single-stranded DNA-dependent DNA helicase activity. GO:0032753 positive regulation of interleukin-4 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032753 stimulation of interleukin-4 production|up-regulation of interleukin-4 production|activation of interleukin-4 production|up regulation of interleukin-4 production|positive regulation of interleukin-4 secretion|positive regulation of IL-4 production|positive regulation of interleukin-4 biosynthetic process|upregulation of interleukin-4 production Any process that activates or increases the frequency, rate, or extent of interleukin-4 production. UBERON:0006924 stomach glandular epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006924 epithelium of gastric gland|gastric gland epithelium A glandular epithelium that lines the stomach. The stomach's glandular epithelium is characterized by the presence of gastric glands. GO:0017112 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0017112 GO:0017111 nucleoside-triphosphatase activity biolink:MolecularActivity go-plus goslim_chembl|goslim_metagenomics http://purl.obolibrary.org/obo/GO_0017111 EC:3.6.1.15|Reactome:R-HSA-8850846|MetaCyc:NUCLEOSIDE-TRIPHOSPHATASE-RXN|RHEA:23680|Reactome:R-HSA-8851538|Reactome:R-HSA-8851234|Reactome:R-HSA-8851089|Reactome:R-HSA-8851110|Reactome:R-HSA-8851494 unspecific diphosphate phosphohydrolase activity|nucleoside triphosphate hydrolase activity|nucleoside triphosphate phosphohydrolase activity|nucleoside 5-triphosphatase activity|NTPase activity|nucleoside triphosphatase activity|apyrase activity|nucleoside-5-triphosphate phosphohydrolase activity Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate. GO:0032752 positive regulation of interleukin-3 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032752 stimulation of interleukin-3 production|up-regulation of interleukin-3 production|activation of interleukin-3 production|up regulation of interleukin-3 production|positive regulation of IL-3 production|positive regulation of interleukin-3 biosynthetic process|upregulation of interleukin-3 production Any process that activates or increases the frequency, rate, or extent of interleukin-3 production. UBERON:0006923 vagina squamous epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006923 vaginal squamous epithelium A squamous epithelium that is part of a vagina. GO:0032751 positive regulation of interleukin-27 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032751 upregulation of interleukin-27 production|positive regulation of IL-27 production|up regulation of interleukin-27 production|activation of interleukin-27 production|stimulation of interleukin-27 production|positive regulation of interleukin-27 anabolism|positive regulation of interleukin-27 biosynthetic process|up-regulation of interleukin-27 production Any process that activates or increases the frequency, rate, or extent of interleukin-27 production. UBERON:0006922 cervix squamous epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006922 cervical squamous epithelium The squamous epithelium of the cervical portio is similar to that of the vagina, except that it is generally smooth and lacks rete pegs. Colposcopically, it appears featureless except for a fine network of vessels which is sometimes visible. The relative opacity and pale pink coloration of the squamous epithelium derives from its multi-layered histology and the location of its supporting vessels below the basement membrane. GO:0017114 obsolete wide-spectrum protease inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017114 wide-spectrum proteinase inhibitor|wide-spectrum protease inhibitor activity OBSOLETE. Stops, prevents or reduces the activity of a protease by a wide-spectrum protease inhibitor. A wide-spectrum protease inhibitor is a protein having a peptide stretch which contains specific cleavage sites for different proteinases enabling inhibition of all four classes of proteinases by formation of a covalent bond between the inhibitor and the protease. GO:0017113 dihydropyrimidine dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017113 Reactome:R-HSA-73616|Reactome:R-HSA-73585|MetaCyc:1.3.1.2-RXN|EC:1.3.1.2|RHEA:18093 dihydrouracil dehydrogenase (NADP+) activity|dehydrogenase, dihydrouracil (nicotinamide adenine dinucleotide phosphate)|dihydrouracil dehydrogenase (NADP)|4,5-dihydrothymine: oxidoreductase activity|DPD|5,6-dihydrouracil:NADP+ 5-oxidoreductase activity|hydropyrimidine dehydrogenase activity|dihydrothymine dehydrogenase activity|DHPDH|dihydropyrimidine dehydrogenase activity|DHU dehydrogenase activity Catalysis of the reaction: 5,6-dihydrouracil + NADP+ = uracil + NADPH + H+. GO:0032750 positive regulation of interleukin-26 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032750 upregulation of interleukin-26 production|positive regulation of IL-26 production|up regulation of interleukin-26 production|activation of interleukin-26 production|stimulation of interleukin-26 production|positive regulation of interleukin-26 biosynthetic process|up-regulation of interleukin-26 production Any process that activates or increases the frequency, rate, or extent of interleukin-26 production. UBERON:0006921 stomach squamous epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006921 A squamous epithelium that is part of a stomach. UBERON:0006920 esophagus squamous epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006920 squamous oesophageal epithelium|squamous epithelium of esophagus|esophageal squamous epithelium A squamous epithelium that is part of a esophagus. GO:0017110 nucleoside-diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017110 RHEA:36799|Reactome:R-HSA-8851129|EC:3.6.1.6|Reactome:R-HSA-8851225|Reactome:R-HSA-8850854|Reactome:R-HSA-8851356|Reactome:R-HSA-8851550|Reactome:R-HSA-8851396|Reactome:R-HSA-2395876|MetaCyc:NUCLEOSIDE-DIPHOSPHATASE-RXN nucleoside-diphosphate phosphohydrolase activity|inosine diphosphatase|type B nucleoside diphosphatase|inosine 5'-diphosphatase|nucleoside diphosphate phosphohydrolase activity|type L nucleoside diphosphatase|nucleoside diphosphate phosphatase activity|NDPase activity|apyrase activity|nucleoside 5'-diphosphatase activity|nucleoside diphosphatase activity Catalysis of the reaction: a nucleoside diphosphate + H2O = a nucleotide + phosphate. GO:0042170 plastid membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042170 Either of the lipid bilayers that surround a plastid and form the plastid envelope. GO:0032749 positive regulation of interleukin-25 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032749 up regulation of interleukin-25 production|activation of interleukin-25 production|stimulation of interleukin-25 production|positive regulation of interleukin-25 biosynthetic process|positive regulation of interleukin-25 secretion|up-regulation of interleukin-25 production|upregulation of interleukin-25 production|positive regulation of IL-25 production Any process that activates or increases the frequency, rate, or extent of interleukin-25 production. CHEBI:45373 sulfanilamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_45373 UBERON:0006909 lumen of digestive tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006909 lumen of alimentary tract|digestive tract lumen|gut lumen|lumen of digestive tract|gut cavity|lumen of gut An anatomical space that surrounded_by a digestive tract. GO:0032748 positive regulation of interleukin-24 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032748 up regulation of interleukin-24 production|activation of interleukin-24 production|stimulation of interleukin-24 production|positive regulation of interleukin-24 biosynthetic process|up-regulation of interleukin-24 production|upregulation of interleukin-24 production|positive regulation of IL-24 production Any process that activates or increases the frequency, rate, or extent of interleukin-24 production. GO:0042172 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042172 GO:0032747 positive regulation of interleukin-23 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032747 up regulation of interleukin-23 production|activation of interleukin-23 production|stimulation of interleukin-23 production|positive regulation of interleukin-23 biosynthetic process|up-regulation of interleukin-23 production|upregulation of interleukin-23 production|positive regulation of IL-23 production Any process that activates or increases the frequency, rate, or extent of interleukin-23 production. UBERON:0006907 slow muscle tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006907 red muscle|slow-twitch skeletal muscle|slow muscle|slow skeletal muscle tissue The darker-colored muscle tissue of some mammals, composed of slow twitch muscle fibers. GO:0042171 lysophosphatidic acid acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042171 LPAAT activity Catalysis of the transfer of acyl groups from an acyl-CoA to lysophosphatidic acid to form phosphatidic acid. GO:0032746 positive regulation of interleukin-22 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032746 activation of interleukin-22 production|stimulation of interleukin-22 production|positive regulation of interleukin-22 biosynthetic process|up-regulation of interleukin-22 production|upregulation of interleukin-22 production|positive regulation of IL-22 production|up regulation of interleukin-22 production Any process that activates or increases the frequency, rate, or extent of interleukin-22 production. GO:0032745 positive regulation of interleukin-21 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032745 stimulation of interleukin-21 production|positive regulation of interleukin-21 biosynthetic process|up-regulation of interleukin-21 production|upregulation of interleukin-21 production|positive regulation of IL-21 production|up regulation of interleukin-21 production|activation of interleukin-21 production Any process that activates or increases the frequency, rate, or extent of interleukin-21 production. UBERON:0006905 mandibular process mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006905 mesenchyme of mandibular prominence|mesenchyme of mandibular process Mesenchyme that is part of a mandibular prominence. GO:0032744 positive regulation of interleukin-20 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032744 stimulation of interleukin-20 production|positive regulation of interleukin-20 biosynthetic process|up-regulation of interleukin-20 production|upregulation of interleukin-20 production|positive regulation of IL-20 production|up regulation of interleukin-20 production|activation of interleukin-20 production Any process that activates or increases the frequency, rate, or extent of interleukin-20 production. UBERON:0006904 head mesenchyme from mesoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006904 mesenchyme derived from head mesoderm|cranial mesoderm|mesenchyme from head mesoderm|head mesenchyme from head mesoderm|head mesenchyme from mesoderm|head mesenchyme derived from mesoderm|head mesoderm A head mesenchyme that develops_from a mesoderm. GO:0032743 positive regulation of interleukin-2 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032743 up regulation of interleukin-2 production|positive regulation of interleukin-2 secretion|positive regulation of IL-2 production|positive regulation of interleukin-2 biosynthetic process|upregulation of interleukin-2 production|stimulation of interleukin-2 production|up-regulation of interleukin-2 production|activation of interleukin-2 production Any process that activates or increases the frequency, rate, or extent of interleukin-2 production. GO:0042178 xenobiotic catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042178 xenobiotic catabolism|xenobiotic degradation|xenobiotic breakdown The chemical reactions and pathways resulting in the breakdown of a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide. GO:0042177 negative regulation of protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042177 down regulation of protein catabolic process|downregulation of protein catabolic process|negative regulation of protein degradation|negative regulation of protein catabolism|negative regulation of protein breakdown|down-regulation of protein catabolic process|inhibition of protein catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. GO:0042179 nicotine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042179 nicotine anabolism|nicotine synthesis|nicotine formation|nicotine biosynthesis The chemical reactions and pathways resulting in the formation of nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine. GO:0042174 negative regulation of sporulation resulting in formation of a cellular spore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042174 down regulation of sporulation|downregulation of sporulation|down-regulation of sporulation|inhibition of sporulation Any process that stops, prevents, or reduces the frequency, rate or extent of sporulation. GO:0042173 regulation of sporulation resulting in formation of a cellular spore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042173 Any process that modulates the frequency, rate or extent of spore formation. GO:0042176 regulation of protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042176 regulation of protein breakdown|regulation of protein catabolism|regulation of protein degradation Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042175 NE-ER network|nuclear membrane-endoplasmic reticulum continuum|nuclear envelope-endoplasmic reticulum continuum|nuclear envelope-ER network|nuclear membrane-ER network|NE-ER continuum|nuclear envelope-endoplasmic reticulum network The continuous network of membranes encompassing the nuclear outer membrane and the endoplasmic reticulum membrane. GO:0017127 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0017127 GO:0017126 nucleologenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017126 nucleolus assembly|nucleolus biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells. GO:0017129 triglyceride binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017129 triacylglycerol binding Interacting selectively and non-covalently with any triester of glycerol. GO:0017128 phospholipid scramblase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017128 Catalysis of the movement of phospholipids from one membrane bilayer leaflet to the other, by an ATP-independent mechanism. GO:0017123 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0017123 GO:0032742 positive regulation of interleukin-19 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032742 positive regulation of IL-19 production|up regulation of interleukin-19 production|activation of interleukin-19 production|stimulation of interleukin-19 production|positive regulation of interleukin-19 biosynthetic process|up-regulation of interleukin-19 production|upregulation of interleukin-19 production Any process that activates or increases the frequency, rate, or extent of interleukin-19 production. UBERON:0006913 lip epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006913 An epithelium that is part of a lip. GO:0017122 protein N-acetylglucosaminyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0017122 O-GlcNAc transferase complex|UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase A protein complex capable of protein N-acetylglucosaminyltransferase activity, the addition of nucleotide-activated sugars onto the polypeptide according to reaction: UDP-N-acetyl-D-glucosamine + protein = UDP + 4-N-(N-acetyl-D-glucosaminyl)-protein. The complex has different compositions in different species: In mammals it is often a homotrimer, in bacteria a heterotetramer of 2 different subunits. GO:0032741 positive regulation of interleukin-18 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032741 up regulation of interleukin-18 production|activation of interleukin-18 production|positive regulation of interleukin-18 secretion|stimulation of interleukin-18 production|positive regulation of interleukin-18 biosynthetic process|up-regulation of interleukin-18 production|upregulation of interleukin-18 production|positive regulation of IL-18 production Any process that activates or increases the frequency, rate, or extent of interleukin-18 production. GO:0017125 deoxycytidyl transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017125 Reactome:R-HSA-110308 deoxycytidyl transferase activity, template-dependent Catalysis of the insertion of a dCMP residue opposite a template abasic site in DNA. GO:0032740 positive regulation of interleukin-17 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032740 positive regulation of CTLA-8 production|up regulation of interleukin-17 production|positive regulation of Cytotoxic T-lymphocyte-associated antigen 8 production|activation of interleukin-17 production|positive regulation of interleukin-17 secretion|stimulation of interleukin-17 production|positive regulation of interleukin-17 biosynthetic process|up-regulation of interleukin-17 production|upregulation of interleukin-17 production|positive regulation of IL-17 production Any process that activates or increases the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines. GO:0017124 SH3 domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017124 Interacting selectively and non-covalently with a SH3 domain (Src homology 3) of a protein, small protein modules containing approximately 50 amino acid residues found in a great variety of intracellular or membrane-associated proteins. GO:0017121 plasma membrane phospholipid scrambling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017121 phospholipid scrambling|PL scrambling The movement of a population of phospholipid molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet, resulting in loss of lipid asymmetry and surface exposure of phosphatidylserine (PS) and phosphatidylethanolamine (PE). GO:0017120 obsolete polyphosphatidylinositol phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017120 polyphosphoinositide phosphatase activity|polyphosphatidylinositol phosphatase activity OBSOLETE. Catalysis of the conversion of phosphatidylinositol-3-phosphate, phosphatidylinositol-4-phosphate, and phosphatidylinositol-3,5-bisphosphate, but not PI-4,5-bisphosphate, to phosphatidylinositol; PPIPase activity is a key regulator of membrane trafficking and actin cytoskeleton organization. GO:0042181 ketone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042181 ketone formation|ketone anabolism|ketone synthesis|ketone biosynthesis The chemical reactions and pathways resulting in the formation of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. GO:0032739 positive regulation of interleukin-16 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032739 positive regulation of interleukin-16 biosynthetic process|up-regulation of interleukin-16 production|upregulation of interleukin-16 production|positive regulation of IL-16 production|up regulation of interleukin-16 production|activation of interleukin-16 production|stimulation of interleukin-16 production Any process that activates or increases the frequency, rate, or extent of interleukin-16 production. GO:0032738 positive regulation of interleukin-15 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032738 up-regulation of interleukin-15 production|upregulation of interleukin-15 production|positive regulation of IL-15 production|up regulation of interleukin-15 production|activation of interleukin-15 production|stimulation of interleukin-15 production|positive regulation of interleukin-15 biosynthetic process Any process that activates or increases the frequency, rate, or extent of interleukin-15 production. GO:0042180 cellular ketone metabolic process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0042180 ketone metabolism The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. GO:0032737 positive regulation of interleukin-14 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032737 up-regulation of interleukin-14 production|upregulation of interleukin-14 production|positive regulation of IL-14 production|up regulation of interleukin-14 production|activation of interleukin-14 production|stimulation of interleukin-14 production|positive regulation of interleukin-14 biosynthetic process Any process that activates or increases the frequency, rate, or extent of interleukin-14 production. GO:0042183 formate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042183 formic acid catabolic process|formate degradation|formic acid catabolism|formate breakdown|formate catabolism The chemical reactions and pathways resulting in the breakdown of formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid. CHEBI:21398 L-altraric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21398 GO:0032736 positive regulation of interleukin-13 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032736 up-regulation of interleukin-13 production|upregulation of interleukin-13 production|positive regulation of IL-13 production|up regulation of interleukin-13 production|activation of interleukin-13 production|stimulation of interleukin-13 production|positive regulation of interleukin-13 biosynthetic process|positive regulation of interleukin-13 secretion Any process that activates or increases the frequency, rate, or extent of interleukin-13 production. CHEBI:21397 L-altrarate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21397 GO:0042182 ketone catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042182 ketone degradation|ketone breakdown|ketone catabolism The chemical reactions and pathways resulting in the breakdown of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. GO:0032735 positive regulation of interleukin-12 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032735 upregulation of interleukin-12 production|positive regulation of NKSF production|positive regulation of IL-12 production|up regulation of interleukin-12 production|activation of interleukin-12 production|stimulation of interleukin-12 production|positive regulation of CLMF production|positive regulation of interleukin-12 biosynthetic process|up-regulation of interleukin-12 production|positive regulation of interleukin-12 secretion Any process that activates or increases the frequency, rate, or extent of interleukin-12 production. GO:0032734 positive regulation of interleukin-11 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032734 upregulation of interleukin-11 production|positive regulation of IL-11 production|up regulation of interleukin-11 production|activation of interleukin-11 production|stimulation of interleukin-11 production|positive regulation of interleukin-11 biosynthetic process|up-regulation of interleukin-11 production|positive regulation of interleukin-11 secretion Any process that activates or increases the frequency, rate, or extent of interleukin-11 production. GO:0032733 positive regulation of interleukin-10 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032733 positive regulation of interleukin-10 secretion|upregulation of interleukin-10 production|positive regulation of IL-10 production|up regulation of interleukin-10 production|activation of interleukin-10 production|stimulation of interleukin-10 production|positive regulation of interleukin-10 biosynthetic process|up-regulation of interleukin-10 production Any process that activates or increases the frequency, rate, or extent of interleukin-10 production. GO:0032732 positive regulation of interleukin-1 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032732 upregulation of interleukin-1 production|stimulation of interleukin-1 production|up-regulation of interleukin-1 production|activation of interleukin-1 production|up regulation of interleukin-1 production|positive regulation of interleukin-1 secretion|positive regulation of IL-1 production|positive regulation of interleukin-1 biosynthetic process Any process that activates or increases the frequency, rate, or extent of interleukin-1 production. GO:0042189 vanillin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042189 vanillin biosynthesis|vanillin synthesis|vanillin formation|vanillic aldehyde biosynthesis|vanillic aldehyde biosynthetic process|vanillin anabolism The chemical reactions and pathways resulting in the formation of vanillin, an aromatic hydrocarbon which occurs naturally in black vanilla bean pods. GO:0042188 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042188 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane catabolism|DDT catabolism|1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane degradation|1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane breakdown|DDT catabolic process The chemical reactions and pathways resulting in the breakdown of 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated broad spectrum contact insecticide. GO:0042185 m-xylene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042185 MetaCyc:PWY-142 m-xylene catabolism|m-xylene degradation|meta-xylene catabolism|meta-xylene catabolic process|m-xylene breakdown The chemical reactions and pathways resulting in the breakdown of m-xylene, 1,3-dimethylbenzene, a colorless, liquid aromatic hydrocarbon. GO:0042184 xylene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042184 xylene catabolism|xylene degradation|xylene breakdown The chemical reactions and pathways resulting in the breakdown of xylene, a mixture of three colorless, aromatic hydrocarbon liquids, ortho-, meta- and para-xylene. GO:0042187 p-xylene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042187 para-xylene catabolic process|p-xylene degradation|para-xylene catabolism|p-xylene breakdown|p-xylene catabolism The chemical reactions and pathways resulting in the breakdown of p-xylene (1,4-dimethylbenzene), a colorless, liquid aromatic hydrocarbon. GO:0042186 o-xylene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042186 o-xylene degradation|o-xylene breakdown|ortho-xylene catabolism|ortho-xylene catabolic process|o-xylene catabolism The chemical reactions and pathways resulting in the breakdown of o-xylene, (1,2-dimethylbenzene) a colorless, liquid aromatic hydrocarbon. GO:0032731 positive regulation of interleukin-1 beta production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032731 upregulation of interleukin-1 beta production|positive regulation of IL-1 beta production|up regulation of interleukin-1 beta production|activation of interleukin-1 beta production|stimulation of interleukin-1 beta production|positive regulation of interleukin-1 beta biosynthetic process|up-regulation of interleukin-1 beta production|positive regulation of interleukin-1 beta secretion Any process that activates or increases the frequency, rate, or extent of interleukin-1 beta production. GO:0032730 positive regulation of interleukin-1 alpha production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032730 stimulation of interleukin-1 alpha production|up-regulation of interleukin-1 alpha production|activation of interleukin-1 alpha production|up regulation of interleukin-1 alpha production|positive regulation of IL-1 alpha production|positive regulation of interleukin-1 alpha biosynthetic process|upregulation of interleukin-1 alpha production|positive regulation of interleukin-1 alpha secretion Any process that activates or increases the frequency, rate, or extent of interleukin-1 alpha production. GO:0032728 positive regulation of interferon-beta production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032728 positive regulation of interferon-beta biosynthetic process|upregulation of interferon-beta production|stimulation of interferon-beta production|up-regulation of interferon-beta production|activation of interferon-beta production|positive regulation of IFN-beta production|up regulation of interferon-beta production|positive regulation of interferon-beta secretion Any process that activates or increases the frequency, rate, or extent of interferon-beta production. GO:0042192 methylmercury biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042192 methylmercury synthesis|methylmercury formation|methylmercury biosynthesis|methylmercury anabolism The chemical reactions and pathways resulting in the formation of methylmercury (MeHg+), a highly toxic organometal. GO:0042191 methylmercury metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042191 methylmercury metabolism The chemical reactions and pathways involving methylmercury (MeHg+), a highly toxic organometal which can accumulate in tissues, particularly in fish species. GO:0032727 positive regulation of interferon-alpha production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032727 upregulation of interferon-alpha production|positive regulation of interferon-alpha secretion|up regulation of interferon-alpha production|activation of interferon-alpha production|stimulation of interferon-alpha production|positive regulation of interferon-alpha biosynthetic process|up-regulation of interferon-alpha production Any process that activates or increases the frequency, rate, or extent of interferon-alpha production. GO:0032726 positive regulation of hepatocyte growth factor production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032726 stimulation of hepatocyte growth factor production|positive regulation of hepatocyte growth factor biosynthetic process|up-regulation of hepatocyte growth factor production|upregulation of hepatocyte growth factor production|positive regulation of scatter factor production|positive regulation of HGF production|up regulation of hepatocyte growth factor production|activation of hepatocyte growth factor production Any process that activates or increases the frequency, rate, or extent of hepatocyte growth factor production. GO:0042194 quinate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042194 quinate biosynthesis|quinate anabolism|quinate synthesis|quinate formation|quinic acid biosynthesis|quinic acid biosynthetic process The chemical reactions and pathways resulting in the formation of quinate, the anion of quinic acid. GO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032725 up regulation of granulocyte macrophage colony-stimulating factor production|activation of granulocyte macrophage colony-stimulating factor production|stimulation of granulocyte macrophage colony-stimulating factor production|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process|up-regulation of granulocyte macrophage colony-stimulating factor production|positive regulation of GM-CSF production|positive regulation of granulocyte macrophage colony stimulating factor production|upregulation of granulocyte macrophage colony-stimulating factor production Any process that activates or increases the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production. GO:0042193 methylmercury catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042193 methylmercury catabolism|methylmercury degradation|methylmercury breakdown The chemical reactions and pathways resulting in the breakdown of methylmercury (MeHg+), a highly toxic organometal. GO:0032724 positive regulation of fractalkine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032724 upregulation of fractalkine production|stimulation of fractalkine production|activation of fractalkine production|up-regulation of fractalkine production|up regulation of fractalkine production Any process that activates or increases the frequency, rate, or extent of fractalkine production. GO:0032723 positive regulation of connective tissue growth factor production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032723 stimulation of connective tissue growth factor production|up-regulation of connective tissue growth factor production|activation of connective tissue growth factor production|positive regulation of Fisp12 production|positive regulation of IGFBP8 production|positive regulation of CCN2 production|positive regulation of Hcs24 production|up regulation of connective tissue growth factor production|positive regulation of hypertrophic chondrocyte-specific gene product 24 production|positive regulation of CTGF production|positive regulation of connective tissue growth factor biosynthetic process|upregulation of connective tissue growth factor production Any process that activates or increases the frequency, rate, or extent of connective tissue growth factor production. GO:0042190 vanillin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042190 vanillin catabolism|vanillic aldehyde catabolic process|vanillin degradation|vanillic aldehyde catabolism|vanillin breakdown The chemical reactions and pathways resulting in the breakdown of vanillin, an aromatic hydrocarbon which occurs naturally in black vanilla bean pods. GO:0032722 positive regulation of chemokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032722 positive regulation of chemokine secretion|up regulation of chemokine production|positive regulation of chemokine biosynthetic process|upregulation of chemokine production|stimulation of chemokine production|activation of chemokine production|up-regulation of chemokine production Any process that activates or increases the frequency, rate, or extent of chemokine production. GO:0032721 negative regulation of lymphotoxin A production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032721 negative regulation of lymphotoxin A biosynthetic process|downregulation of lymphotoxin A production|negative regulation of LTA production|down regulation of lymphotoxin A production|inhibition of lymphotoxin A production|negative regulation of lymphotoxin-alpha production|down-regulation of lymphotoxin A production|negative regulation of TNF-beta production|negative regulation of tumor necrosis factor-beta production Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphotoxin A production. GO:0042199 cyanuric acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042199 cyanuric acid metabolism The chemical reactions and pathways involving cyanuric acid, a suspected gastrointestinal or liver toxicant, and a potential degradation product of triazine herbicides, such as atrazine and simazine. It is widely used for the stabilization of available chlorine in swimming pool water and is also the starting compound for the synthesis of many organic derivatives. GO:0042196 chlorinated hydrocarbon metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042196 chlorinated hydrocarbon metabolism The chemical reactions and pathways involving chlorinated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with chlorine atoms. GO:0042195 aerobic gallate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042195 aerobic gallic acid catabolism|aerobic gallic acid catabolic process|aerobic gallate catabolism|aerobic gallate degradation|aerobic gallate breakdown The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, in the presence of oxygen. GO:0042198 nylon metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042198 nylon metabolism The chemical reactions and pathways involving nylon, a polymer where the main polymer chain comprises recurring amide groups; these compounds are generally formed from combinations of diamines, diacids and amino acids. GO:0032729 positive regulation of interferon-gamma production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032729 positive regulation of interferon-gamma secretion|positive regulation of interferon-gamma biosynthetic process|positive regulation of type II interferon production|up-regulation of interferon-gamma production|upregulation of interferon-gamma production|up regulation of interferon-gamma production|activation of interferon-gamma production|stimulation of interferon-gamma production Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon. GO:0042197 halogenated hydrocarbon metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042197 halogenated hydrocarbon metabolism The chemical reactions and pathways involving halogenated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with halogen atoms. Halogens include fluorine, chlorine, bromine and iodine. GO:0017109 glutamate-cysteine ligase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0017109 gamma-glutamylcysteine synthetase complex An enzyme complex that catalyzes the ligation of glutamate to cysteine, forming glutamylcysteine. GO:0017108 5'-flap endonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017108 Reactome:R-HSA-174441|Reactome:R-HSA-69152|Reactome:R-HSA-5651782|Reactome:R-HSA-5687664|Reactome:R-HSA-110363|Reactome:R-HSA-174446 5' flap endonuclease activity Catalysis of the cleavage of a 5' flap structure in DNA, but not other DNA structures; processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. CHEBI:59991 4-(hydroxylamino)-N,N-dimethylaniline biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59991 CHEBI:59990 N,N-dimethyl-4-nitrosoaniline biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59990 GO:0017105 acyl-CoA delta11-desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017105 EC:1.14.19.5 acyl-CoA delta(11)-desaturase activity|acyl-CoA D11-desaturase activity Catalysis of the reaction: acyl-CoA + reduced acceptor + O2 = delta11-acyl-CoA + acceptor + 2 H2O. GO:0017104 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0017104 GO:0017107 obsolete anion exchanger adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017107 OBSOLETE. The binding activity of a molecule that brings together an anion exchanger and one or more other molecules, permitting them to function in a coordinated way. GO:0017106 obsolete activin inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017106 activin inhibitor activity OBSOLETE. Acts to negatively regulate the activity of activin, a nonsteroidal regulator synthesized in the pituitary gland and gonads that stimulates the secretion of follicle-stimulating hormone. GO:0032720 negative regulation of tumor necrosis factor production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032720 downregulation of tumor necrosis factor production|inhibition of cachectin production|down regulation of tumor necrosis factor production|inhibition of tumor necrosis factor production|negative regulation TNF production|down-regulation of tumor necrosis factor production|negative regulation of tumor necrosis factor secretion|negative regulation tumor necrosis factor-alpha production|negative regulation TNF-alpha production|negative regulation of tumor necrosis factor biosynthetic process Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production. GO:0017101 aminoacyl-tRNA synthetase multienzyme complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0017101 multisynthetase complex|aminoacyl-tRNA synthetase complex A multienzyme complex found in all multicellular eukaryotes composed of eight proteins with aminoacyl-tRNA synthetase activities (abbreviated as: ArgRS, AspRS, GluProRS, GlnRS, IleRS, LeuRS, LysRS, MetRS where RS is the enzyme, preceded by the amino acid it uses as a substrate) as well as three non-synthetase proteins (p43, p38, and p18) with diverse functions. Several of these subunits are known dimers, so the total polypeptide count in the multisynthetase complex is at least fifteen. All of the enzymes in this assembly catalyze the same reaction, the covalent attachment of an amino acid to either the 2'- or 3'-hydroxyl of the 3'-terminal adenosine of tRNA, but using different substrates. GO:0017100 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0017100 GO:0017103 UTP:galactose-1-phosphate uridylyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017103 EC:2.7.7.10|MetaCyc:UTPHEXPURIDYLYLTRANS-RXN|KEGG_REACTION:R00502|RHEA:14209 alpha-D-galactose 1-phosphate uridylyltransferase activity|galactose 1-phosphate uridyltransferase activity|UTP:hexose-1-phosphate uridylyltransferase activity|UTP-hexose-1-phosphate uridylyltransferase activity|UDPgalactose pyrophosphorylase activity|uridine diphosphate galactose pyrophosphorylase activity|UTP:alpha-D-hexose-1-phosphate uridylyltransferase activity|uridine diphosphogalactose pyrophosphorylase activity|galactose-1-phosphate uridylyltransferase activity|Gal-1-P uridylyltransferase activity|galactose 1-phosphate uridylyltransferase activity Catalysis of the reaction: alpha-D-galactose 1-phosphate + UTP = diphosphate + UDP-D-galactose. CHEBI:59999 chemical substance biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59999 GO:0017102 methionyl glutamyl tRNA synthetase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0017102 A complex consisting of methionyl- and glutamyl-tRNA synthetases. The tRNA synthetases present in the complex bind to their cognate tRNAs more efficiently than they do as monomers. CHEBI:59998 1,2-diacyl-sn-glycerol 3-diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59998 CHEBI:59997 EC 1.14.18.1 (tyrosinase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59997 CHEBI:59996 1,2-diacyl-sn-glycerol 3-diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59996 CHEBI:84949 (11E)-Delta(11)-fatty acyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84949 CHEBI:84948 11,12-saturated fatty acyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84948 CHEBI:84947 (11Z)-Delta(11)-fatty acyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84947 CHEBI:84940 ethyl oleate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84940 CHEBI:60980 beta-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60980 CHEBI:60982 methyl galactoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60982 CHEBI:60981 UDP-rhamnose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60981 OBO:GOCHE_24621 substance with hormone role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_24621 CHEBI:137097 9-(octadecanoyloxy)octadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137097 CHEBI:84955 7-demethylmitomycin A(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84955 CHEBI:84952 7-demethylmitomycin B(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84952 CHEBI:60991 2-hydroxyethylphosphonic acid(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60991 CHEBI:60997 (2R)-3-sulfopropanediol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60997 CHEBI:60996 (2R)-3-sulfopropanediol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60996 CHEBI:70315 eburicol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70315 GO:0140409 positive regulation of mRNA alternative polyadenylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140409 Any process that activates or increases the frequency, rate or extent of mRNA alternative polyadenylation. GO:0140408 regulation of mRNA alternative polyadenylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140408 Any process that modulates the frequency, rate or extent of mRNA alternative polyadenylation. CHEBI:137084 9-[(9Z)-hexadecenoyloxy]octadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137084 CHEBI:137083 13-[(9Z)-octadecenoyloxy]octadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137083 CHEBI:137082 12-[(9Z)-octadecenoyloxy]octadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137082 CHEBI:84969 cholesteryl (5Z,8Z,11Z,14Z,17Z-eicosapentaenoate) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84969 CHEBI:84968 1,2-dipalmitoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate)(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84968 GO:0140403 effector-mediated suppression of host innate immune response by symbiont biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140403 effector-dependent suppression of host immune innate response by symbiont|effector-mediated suppression of host immune innate response by symbiont|effector triggered suppression of host immune innate response by symbiont|effector dependent suppression of host immune innate response by symbiont|effector-mediated suppression of host innate immunity|effector-triggered suppression of host immune innate response by symbiont A process mediated by a molecule secreted by a symbiont that results in the suppression of a host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:84966 ipsdienone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84966 GO:0140405 spindle pole body-led chromosome movement during mitotic interphase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140405 A microtubule-based process in which chromosomes migrate as a result of rapid spindle pole body (SPB) and centrosome oscillations during mitotic interphase. GO:0140404 effector-mediated modulation of host innate immune response by symbiont biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140404 effector mediated modulation of host immune response by symbiont|effector-triggered modulation of host immune response by symbiont|effector-dependent modulation of host immune response by symbiont|effector triggered modulation of host immune response by symbiont|effector-mediated modulation of host immunity A process mediated by a molecule secreted by a symbiont that results in the modulation (either activation or suppression) of a host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:84963 13-hydroxy-gamma-tocopherol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84963 GO:0140407 L-alanine:proton antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140407 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + L-alanine(in) = H+(in) + L-alanine(out). CHEBI:84962 13-hydroxy-alpha-tocopherol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84962 GO:0140406 L-alanine export across the plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140406 The directed movement of L-alanine from inside of a cell, across the plasma membrane and into the extracellular region. CHEBI:137077 2beta-hydroxytestosterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137077 CHEBI:137076 1beta-hydroxytestosterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137076 CHEBI:137091 13-(octadecanoyloxy)octadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137091 CHEBI:84976 alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(d18:1/22:1) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84976 CHEBI:84975 acarbose 7(IV)-phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84975 CHEBI:84973 oleoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84973 CHEBI:84971 (2E,6E,10E)-geranylgeranic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84971 CHEBI:84970 (4R)-ipsdienol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84970 CHEBI:137086 13-[(9Z)-hexadecenoyloxy]octadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137086 CHEBI:137085 12-[(9Z)-hexadecenoyloxy]octadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137085 CHEBI:137089 12-(octadecanoyloxy)octadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137089 CHEBI:137062 7-oxo-5alpha-cholestan-3beta-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137062 CHEBI:137061 cholesta-5,7-dien-3beta,24S-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137061 CHEBI:84985 (2E,6E,10E)-omega-hydroxyfarnesyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84985 CHEBI:84984 alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(d18:1/24:2) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84984 CHEBI:84981 2-aminoadipate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84981 GO:0017199 N-terminal peptidyl-threonine acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017199 RESID:AA0052 The acetylation of the N-terminal threonine of proteins to form the derivative N-acetyl-L-threonine; catalyzed by peptide alpha-N-acetyltransferase. CHEBI:137053 (24Z),26-hydroxydesmosterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137053 GO:0017196 N-terminal peptidyl-methionine acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017196 RESID:AA0049 The acetylation of the N-terminal methionine of proteins to form the derivative N-acetyl-L-methionine. GO:0017195 N-terminal peptidyl-lysine N2-acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017195 RESID:AA0048 The acetylation of the N-terminal lysine of proteins to form the derivative N2-acetyl-L-lysine. The occurrence of this modification has not been confirmed. CHEBI:137057 cholesta-5,7-dien-3beta,25-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137057 GO:0017198 N-terminal peptidyl-serine acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017198 RESID:AA0051 The acetylation of the N-terminal serine of proteins to form the derivative N-acetyl-L-serine. GO:0017197 N-terminal peptidyl-proline acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017197 RESID:AA0050 The acetylation of the N-terminal proline of proteins to form the derivative N-acetyl-L-proline. CHEBI:84996 3-oxopropanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84996 CHEBI:84995 3-hydroxy-3-(methylthio)propanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84995 CHEBI:84994 3-(methylthio)acryloyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84994 CHEBI:84992 3-methylpalmitoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84992 CHEBI:84991 alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(d18:1/24:2) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84991 CHEBI:84990 gamma-carboxy-L-glutamate(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84990 CHEBI:137063 cholestanol 7alpha,8alpha-epoxide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137063 GO:0017181 peptidyl-diphthine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017181 peptidyl-diphthine degradation|peptidyl-diphthine breakdown|peptidyl-diphthine catabolism The chemical reactions and pathways resulting in the breakdown of peptidyl-diphthine, a modified histidine residue. GO:0017180 peptidyl-diphthine biosynthetic process from peptidyl-histidine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017180 peptidyl-diphthine anabolism from peptidyl-histidine|peptidyl-diphthine synthesis from peptidyl-histidine|peptidyl-diphthine formation from peptidyl-histidine The chemical reactions and pathways resulting in the formation of peptidyl-diphthine from other compounds, including peptidyl-histidine. GO:0017183 peptidyl-diphthamide biosynthetic process from peptidyl-histidine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017183 RESID:AA0040 peptidyl-diphthamide anabolism from peptidyl-histidine|peptidyl-diphthamide synthesis from peptidyl-histidine|peptidyl-diphthamide formation from peptidyl-histidine The modification of peptidyl-histidine to 2'-(3-carboxamido-3-(trimethylammonio)propyl)-L-histidine, known as diphthamide, found in translation elongation factor EF-2. The process occurs in eukaryotes and archaea but not eubacteria. GO:0017182 peptidyl-diphthamide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017182 peptidyl-diphthamide metabolism The chemical reactions and pathways involving peptidyl-diphthamide, a modified histidine residue. CHEBI:137040 short chain fatty acyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137040 GO:0042101 T cell receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042101 Wikipedia:T_cell_receptor T lymphocyte receptor complex|TCR complex|TCR|T-lymphocyte receptor complex|T-cell receptor complex A protein complex that contains a disulfide-linked heterodimer of T cell receptor (TCR) chains, which are members of the immunoglobulin superfamily, and mediates antigen recognition, ultimately resulting in T cell activation. The TCR heterodimer is associated with the CD3 complex, which consists of the nonpolymorphic polypeptides gamma, delta, epsilon, zeta, and, in some cases, eta (an RNA splice variant of zeta) or Fc epsilon chains. GO:0042100 B cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042100 B lymphocyte proliferation|B-cell proliferation|B-lymphocyte proliferation The expansion of a B cell population by cell division. Follows B cell activation. GO:0042103 positive regulation of T cell homeostatic proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042103 upregulation of T cell homeostatic proliferation|positive regulation of resting T cell proliferation|positive regulation of T-cell homeostatic proliferation|stimulation of T cell homeostatic proliferation|up-regulation of T cell homeostatic proliferation|activation of T cell homeostatic proliferation|positive regulation of T-lymphocyte homeostatic proliferation|up regulation of T cell homeostatic proliferation|positive regulation of T lymphocyte homeostatic proliferation Any process that activates or increases the rate or extent of resting T cell proliferation. GO:0042102 positive regulation of T cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042102 upregulation of T cell proliferation|stimulation of T cell proliferation|activation of T cell proliferation|up-regulation of T cell proliferation|positive regulation of T-lymphocyte proliferation|up regulation of T cell proliferation|positive regulation of T lymphocyte proliferation Any process that activates or increases the rate or extent of T cell proliferation. GO:0042109 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042109 GO:0042108 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042108 CHEBI:137039 8,9-epoxy-(5Z,11Z,14Z)-icosatrienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137039 GO:0042105 alpha-beta T cell receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042105 alpha-beta T lymphocyte receptor complex|alpha-beta T-lymphocyte receptor complex|alpha-beta TCR complex|alpha-beta T-cell receptor complex A T cell receptor complex in which the TCR heterodimer comprises alpha and beta chains, associated with the CD3 complex; recognizes a complex consisting of an antigen-derived peptide bound to a class I or class II MHC protein. GO:0042104 positive regulation of activated T cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042104 activation of activated T cell proliferation|up-regulation of activated T cell proliferation|positive regulation of activated T-lymphocyte proliferation|up regulation of activated T cell proliferation|positive regulation of activated T lymphocyte proliferation|upregulation of activated T cell proliferation|stimulation of activated T cell proliferation|positive regulation of activated T-cell proliferation Any process that activates or increases the rate or extent of activated T cell proliferation. GO:0042107 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042107 GO:0042106 gamma-delta T cell receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042106 gamma-delta T-lymphocyte receptor complex|gamma-delta TCR complex|gamma-delta T-cell receptor complex|gamma-delta T lymphocyte receptor complex A T cell receptor complex in which the TCR heterodimer comprises gamma and delta chains, associated with the CD3 complex; recognizes antigen directly, without a requirement for processing and presentation by an MHC protein. GO:0017178 diphthine-ammonia ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017178 RHEA:19753|MetaCyc:DIPHTINE--AMMONIA-LIGASE-RXN|EC:6.3.1.14|KEGG_REACTION:R03613|Reactome:R-HSA-5358475 diphthine:ammonia ligase (ADP-forming)|diphthamide synthase activity|diphthamide synthetase activity Catalysis of the reaction: ATP + diphthine + NH(4)(+) = ADP + diphthamide + H(+) + phosphate. CHEBI:137033 N,N-dihydroxy-L-hexahomomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137033 GO:0017177 glucosidase II complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0017177 alpha-glucosidase II complex A heterodimeric complex that catalyzes the trimming of glucose residues from N-linked core glycans on newly synthesized glycoproteins. CHEBI:137032 19-oxo-5alpha-dihydrotestosterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137032 CHEBI:137031 19-hydroxy-5alpha-dihydrotestosterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137031 GO:0017179 peptidyl-diphthine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017179 peptidyl-diphthine metabolism The chemical reactions and pathways involving peptidyl-diphthine, a modified histidine residue. CHEBI:137030 N,N-dihydroxy-L-pentahomomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137030 GO:0017174 glycine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017174 Reactome:R-HSA-6798317|EC:2.1.1.156|MetaCyc:2.1.1.162-RXN|EC:2.1.1.162|MetaCyc:GLYCINE-N-METHYLTRANSFERASE-RXN|EC:2.1.1.20|KEGG_REACTION:R00367|RHEA:19937 GNMT|S-adenosyl-L-methionine:glycine methyltransferase activity|S-adenosyl-L-methionine:glycine N-methyltransferase activity|glycine methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + glycine = S-adenosyl-L-homocysteine + sarcosine. CHEBI:137037 18-hydroxy-5alpha-dihydrotestosterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137037 GO:0017173 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0017173 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017176 MetaCyc:2.4.1.198-RXN|EC:2.4.1.198|RHEA:14789 UDP-N-acetyl-D-glucosamine:1-phosphatidyl-1D-myo-inositol 6-(N-acetyl-alpha-D-glucosaminyl)transferase activity|UDP-N-acetyl-D-glucosamine:phosphatidylinositol N-acetyl-D-glucosaminyltransferase activity|uridine diphosphoacetylglucosamine alpha-1,6-acetyl-D-glucosaminyltransferase activity|uridine diphosphoacetylglucosamine alpha1,6-acetyl-D-glucosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + phosphatidylinositol = UDP + N-acetyl-D-glucosaminylphosphatidylinositol. GO:0017175 obsolete IMP-GMP specific 5'-nucleotidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017175 IMP-GMP specific 5'-nucleotidase activity OBSOLETE. Catalysis of the conversion of 5'-ribonucleotides to ribonucleosides and phosphate, with specificity for IMP or GMP 5'-ribonucleotides and H2O as a nucleophile. GO:0017192 N-terminal peptidyl-glutamine acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017192 RESID:AA0045 The acetylation of a glutamine residue in protein to form the N5-methyl-L-glutamine derivative. The occurrence of this modification has not been confirmed. Its annotation in sequence databases is either due to the misidentification of 2-pyrrolidone-5-carboxylic acid, or to inappropriate homolog comparisons when proteolytic modification is more probable. GO:0017191 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0017191 GO:0017194 N-terminal peptidyl-isoleucine acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017194 RESID:AA0047 The acetylation of the N-terminal isoleucine of proteins to form the derivative N-acetyl-L-isoleucine. The occurrence of this modification has not been confirmed. GO:0017193 N-terminal peptidyl-glycine acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017193 RESID:AA0046 The acetylation of the N-terminal glycine of proteins to form the derivative N-acetylglycine. CHEBI:137050 14,15-epoxy-(5Z,8Z,11Z)-icosatrienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137050 GO:0017190 N-terminal peptidyl-aspartic acid acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017190 RESID:AA0042 The acetylation of the N-terminal aspartic acid of proteins; catalyzed by aspartate N-acetyltransferase. GO:0042112 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042112 GO:0042111 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042111 GO:0042114 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042114 GO:0042113 B cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042113 B lymphocyte activation|B-lymphocyte activation|B-cell activation The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. GO:0042110 T cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042110 T lymphocyte activation|T-lymphocyte activation|T-cell activation The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. GO:0042119 neutrophil activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042119 The change in morphology and behavior of a neutrophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. CHEBI:137049 16alpha,17alpha-dihydroxypregnenolone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137049 GO:0042116 macrophage activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042116 macrophage polarization A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. GO:0042115 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042115 GO:0042118 endothelial cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042118 The change in morphology and behavior of an endothelial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. GO:0042117 monocyte activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042117 The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. GO:0017189 N-terminal peptidyl-alanine acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017189 RESID:AA0041 The acetylation of the N-terminal alanine of proteins; catalyzed by peptide alpha-N-acetyltransferase or other enzymes of this class, such as ribosomal-protein-alanine N-acetyltransferase. CHEBI:137044 N-[(+)-12-hydroxy-7-isojasmonyl]isoleucine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137044 GO:0017188 aspartate N-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0017188 Reactome:R-HSA-8954468|EC:2.3.1.17|MetaCyc:ASPARTATE-N-ACETYLTRANSFERASE-RXN|KEGG_REACTION:R00487|RHEA:14165 L-aspartate N-acetyltransferase activity|aspartate acetyltransferase activity|acetyl-CoA:L-aspartate N-acetyltransferase activity Catalysis of the reaction: L-aspartate + acetyl-CoA = N-acetyl-L-aspartate + CoA + H(+). CHEBI:137043 N-[(+)-7-isojasmonyl]-L-isoleucine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137043 CHEBI:137041 quinine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137041 GO:0017185 peptidyl-lysine hydroxylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017185 The hydroxylation of peptidyl-lysine to form peptidyl-hydroxylysine. GO:0017184 peptidyl-diphthamide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017184 peptidyl-diphthamide degradation|peptidyl-diphthamide catabolism|peptidyl-diphthamide breakdown The chemical reactions and pathways resulting in the breakdown of peptidyl-diphthamide, a modified histidine residue. CHEBI:137047 11,12-epoxy-(5Z,8Z,14Z)-icosatrienoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137047 GO:0017187 peptidyl-glutamic acid carboxylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017187 RESID:AA0032 The gamma-carboxylation of peptidyl-glutamic acid; catalyzed by the vitamin K dependent gamma-glutamyl carboxylase. CHEBI:137046 6beta,16alpha,17alpha-trihydroxyprogesterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137046 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0017186 RESID:AA0031 2-pyrrolidone-5-carboxylic acid biosynthesis|2-pyrrolidone-5-carboxylic acid biosynthetic process|peptidyl-pyroglutamic acid formation, using glutaminyl-peptide cyclotransferase|peptidyl-pyroglutamic acid synthesis, using glutaminyl-peptide cyclotransferase|peptidyl-pyroglutamic acid anabolism, using glutaminyl-peptide cyclotransferase The chemical reactions and pathways resulting in the formation of peptidyl-pyroglutamic acid, catalyzed by glutaminyl-peptide cyclotransferase. CHEBI:59908 ecgoninium methyl ester(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59908 CHEBI:59907 F420-0(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59907 CHEBI:59906 2-phosphonato-L-lactate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59906 CHEBI:59905 dopaminium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59905 CHEBI:59904 7,8-didemethyl-8-hydroxy-5-deazariboflavin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59904 CHEBI:59903 thermosperminium(4+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59903 GO:0140467 integrated stress response signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140467 Wikipedia:Integrated_stress_response ISR The series of molecular signals generated in response to diverse stress stimuli required to restore cellular homeostasis. The core event in this pathway is the phosphorylation of eIF2 alpha by one of four members of the eIF2a kinase family (EIF2AK1/HRI, EIF2AK2/PKR, EIF2AK3/PERK and EIF2AK4/GCN2), which leads to a decrease in global protein synthesis and the induction of selected genes, including the transcription factor ATF4, that together promote cellular recovery. CHEBI:35935 pent-4-enoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35935 GO:0140466 iron-sulfur cluster export from the mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140466 The directed movement of iron sulfur clusters from inside the mitochondrion into the cytosol by crossing the inner mitochondrial membrane. GO:0140469 GCN2-mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140469 regulation of eIF2 alpha phosphorylation by amino acid starvation|EIF2AK4-mediated signaling A series of reactions in which a signal is passed on to downstream proteins within the cell via GCN2 (also known as EIF2AK4), an intracellular protein kinase that is activated by stress signals, such as amino acid starvation. GO:0140468 HRI-mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140468 EIF2AK1-mediated signaling A series of reactions in which a signal is passed on to downstream proteins within the cell via HRI (also known as EIF2AK1), an intracellular protein kinase that is activated by stress signals, such as heme deficiency, oxidative stress, osmotic shock, mitochondrial dysfunction and heat shock. CHEBI:35936 pent-4-enoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35936 GO:0140461 subtelomeric heterochromatin organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140461 The organization of chromatin into heterochromatin at the subtelomeric region of a chromosome. GO:0140460 response to Gram-negative bacterium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140460 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a Gram-negative bacterium. GO:0140463 chromatin adaptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140463 protein-chromatin adaptor activity|chromatin adaptor activity|chromatin recruitment|chromatin receptor The binding activity of a molecule that brings together a protein or a protein complex with a nucleosome, to establish or maintain the chromatin localization of the protein, or protein complex. CHEBI:35931 delta-amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35931 GO:0140462 pericentric heterochromatin organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140462 The organization of chromatin into heterochromatin at the pericentric region of a chromosome. GO:0140464 silent mating-type cassette heterochromatin organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140464 The organization of chromatin into heterochromatin at a silent mating-type cassette locus. CHEBI:35932 3-methyl-2-oxovaleric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35932 CHEBI:60904 4-hydroxy-L-threonine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60904 CHEBI:60903 N-(4-aminobenzoyl)-L-glutamate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60903 CHEBI:60908 (2R)-2-hydroxy-2-methylbutanenitrile biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60908 CHEBI:60907 (S)-ethylmalonyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60907 CHEBI:60909 (S)-ethylmalonyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60909 GO:0140456 initial meiotic spindle pole body separation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140456 initial spindle pole body separation involved in meiosis I|meiotic spindle pole body duplication The release of duplicated meiotic spindle pole bodies (SPBs). GO:0140455 cytoplasm protein quality control biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140455 The chemical reactions and pathways resulting in the breakdown of misfolded proteins in the cytoplasm, which are either targeted to cytoplasmic proteasomes for degradation or protected by chaperones to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding. CHEBI:11955 4-amino-3-hydroxybutanoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_11955 GO:0140458 pre-transcriptional gene silencing by RNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140458 Any gene inactivation (silencing) process mediated by small RNA molecules that occur before the trancription begins. GO:0140457 protein demethylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140457 Catalysis of the removal of a methyl group from a protein. GO:0140459 response to Gram-positive bacterium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140459 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a Gram-positive bacterium. GO:0140450 protein targeting to Golgi apparatus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140450 The process of targeting specific proteins to the Golgi apparatus. Usually requires an organelle-specific protein sequence motif or a protein modification (for example a palmitoylation). CHEBI:35940 protirelin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35940 CHEBI:35942 neurotransmitter agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35942 GO:0140451 counting factor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140451 A secreted multiprotein complex composed of 4 proteins, regulating group size during aggregation in cooperative development. An example of this complex is found in Dictyostelium discoideum. CHEBI:35941 serotonergic agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35941 GO:0140454 protein aggregate center assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140454 PAC assembly|protein aggregate center formation|protein aggregate centre assembly The reversible aggregation of misfolded proteins and chaperones, formed to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding. CHEBI:11951 4-acetamidobutanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_11951 CHEBI:60911 racemate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60911 GO:0140453 protein aggregate center biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140453 PAC|protein aggregate centre Reversible aggregate of misfolded proteins and chaperones formed to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding. CHEBI:60913 ganglioside GT1b biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60913 GO:0140489 molecular template activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140489 The action of a molecule that provides a shape or a sequence mimicking or complementary to the final product, providing template for copying the original molecule's shape or sequence. GO:0140488 heme receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140488 Binding specifically to heme to deliver it to a transport vesicle. CHEBI:35915 sterol ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35915 CHEBI:11987 4-formylbenzenesulfonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_11987 GO:0140481 ABC-type iron-sulfur cluster transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140481 TC:3.A.1.210.1 ATPase-coupled Fe-S cluster transmembrane transporter activity|ATPase-coupled iron-sulfur cluster transmembrane transporter activity Catalysis of the reaction: ATP + H2O + iron-sulfur cluster(in) = ADP + phosphate + iron-sulfur cluster(out). GO:0140480 mitotic spindle pole body insertion into the nuclear envelope biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140480 establishment of spindle pole body localization to nuclear envelope|establishment of spindle pole body localisation in nuclear envelope|establishment of spindle pole body localization in nuclear envelope A process in which the duplicated mitotic spindle pole body is inserted into a fenestra which opens in the nuclear envelope in early mitosis, and is subsequently tethered to the membrane. GO:0140483 outer kinetochore adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140483 The binding activity of a protein that brings the kinetochore and another molecule into contact, permitting those molecules to function in a coordinated way. GO:0140482 iron sensor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140482 Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of iron. GO:0140485 5-aminolevulinic acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140485 RHEA:64816 Enables the transfer of 5-aminolevulinic acid from one side of a membrane to the other. CHEBI:11986 4-fluoro-L-threonine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_11986 GO:0140484 5-aminolevulinic acid import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140484 The directed movement of 5-aminolevulinic acid from outside of a cell, across the plasma membrane and into the cytosol. GO:0140487 metal ion sequestering activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140487 The selective interaction of a protein with a metal ion to prevent it from interacting with sensitive components of a biological system. GO:0140486 zinc ion sequestering activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140486 The selective interaction of a protein with a zinc ion to prevent it from interacting with sensitive components of a biological system. CHEBI:35910 2-oxo monocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35910 CHEBI:60924 keratan sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60924 CHEBI:60926 amino monosaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60926 CHEBI:60929 arbutin 6-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60929 CHEBI:35924 peroxol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35924 CHEBI:35923 hydroperoxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35923 GO:0140479 ergothioneine biosynthesis from histidine via hercynylcysteine sulfoxide synthase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140479 A biosynthetic process that results in the formation of ergothioneine from histidine via a set of steps including the hercynylcysteine sulfoxide synthase reaction, which converts N-alpha,N-alpha,N-alpha-trimethyl-L-histidine directly to hercynylcysteine sulfoxide. GO:0140472 cell cortex of non-growing cell tip biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140472 The region directly beneath the plasma membrane at the cell tip at which no growth takes place. GO:0140471 positive regulation of transepithelial migration of symbiont in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140471 positive regulation of transmigration of symbiont in host Any process that activates or increases the frequency, rate or extent of transepithelial migration of symbiont in host. GO:0140474 mitochondrion-endoplasmic reticulum membrane tether activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140474 endoplasmic reticulum-mitochondrion membrane adaptor activity|mitochondrion-endoplasmic reticulum membrane adaptor activity|ER-mitochondrion membrane adaptor activity|mitochondrion-ER membrane tether activity|mitochondrion-ER membrane adaptor activity|ER-mitochondrion membrane tether activity|endoplasmic reticulum-mitochondrion membrane tether activity The binding activity of a molecule that brings together a mitochondrion and an ER membrane either via membrane lipid binding or by interacting with a mitochondrial outer membrane protein, to establish or maintain the localization of the mitochondrion. GO:0140473 telomere-nuclear envelope anchor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140473 nuclear envelope-telomere anchor activity|telomere-nuclear envelope anchoring activity The binding activity of a molecule that brings together the telomeric region of a chromosome and the inner nuclear membrane by interacting with both the telomere and the nuclear membrane, in order to establish and maintain the telomeric location. CHEBI:60933 (E)-4-(trimethylammonio)but-2-enoyl-CoA(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60933 GO:0140475 spindle pole body anchor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140475 The binding activity of a protein that brings together the spindle pole body and one or more other molecules, permitting them to function in a coordinated way. CHEBI:60932 (R)-carnitinyl-CoA(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60932 CHEBI:11972 4-carboxymethylenebut-2-en-4-olide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_11972 CHEBI:60935 sinapate ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60935 CHEBI:60938 glucuronoxylan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60938 CHEBI:84904 (9Z,12Z)-18-hydroxyoctadecadienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84904 GO:0140423 effector-mediated suppression of pattern-triggered immunity signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140423 effector-mediated suppression of PTI signalling|effector-mediated suppression of host pattern recognition receptor signaling|effector-mediated suppression of host PRR signalling|effector-mediated suppression of pattern-triggered immunity signaling|effector-mediated suppression of host PRR signaling A process mediated by a molecule secreted by a symbiont that results in the suppression of a pattern-triggered immunity PTI signaling pathway. PTI signaling pathways are found in plants. GO:0140425 galactose import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140425 The directed movement of galactose from outside of a cell, across the plasma membrane and into the cytosol. CHEBI:84900 12-deoxynogalonate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84900 GO:0140426 PAMP-triggered immunity signalling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140426 PTI signalling|MAMP-triggered immunity signalling|pathogen-associated molecular pattern signalling Any series of molecular signals generated as a consequence of a pattern recognition receptor (PRR) binding to one of its physiological ligands to activate a plant innate immune response. PAMP-triggered immunity PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species. GO:0140429 positive regulation of mitotic sister chromatid biorientation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140429 repair of mitotic merotelic kinetochore attachment defect|repair of mitotic merotelic kinetochore attachment defects|correction of syntelic kinetochore attachment, mitotic|correction of mono-orientation defects|repair of mitotic mono-orientation defect|repair of mitotic mono-orientation defects|correction of merotelic kinetochore attachment, mitotic Any process that activates or increases the frequency, rate or extent of mitotic sister chromatid biorientation, the mitotic cell cycle process in which sister chromatids establish stable, end-on attachments to the plus ends of microtubules emanating from opposite spindle poles, oriented such that separation can proceed. CHEBI:60940 D-mannosyl-D-glyceric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60940 CHEBI:60941 prenylcysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60941 GO:0140421 endocytic heme import into cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140421 heme assimilation The directed movement into cell of externally available heme by receptor-mediated endocytosis. GO:0140420 heme import into cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140420 heme assimilation The directed movement of a heme from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis. CHEBI:60943 5-HETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60943 CHEBI:60948 alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-D-Glc biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60948 UBERON:0016398 lymph node of lower limb biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016398 A lymph node that is part of a hindlimb. GO:0140412 zinc:bicarbonate symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140412 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: zinc(out) + HCO3-(out) = zinc(in) + HCO3-(in). CHEBI:35902 oxo monocarboxylic acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35902 CHEBI:84913 3-amino-N-(trans-3-carbamoyloxirane-2-carbonyl)-L-alanine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84913 CHEBI:84912 dapdiamide E zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84912 GO:0140414 phosphopantetheine-dependent carrier activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140414 carrier protein activity Binding a substrate via a thioester at the terminal thiol of a covalentely linked phosphopantetheine prosthetic group and mediating protein-protein interactions with cognate enzymes for processing or offloading of the thiol-bound substrate. CHEBI:35903 oxo carboxylic acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35903 GO:0140413 zinc:bicarbonate:selenite symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140413 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: zinc(out) + HCO3-(out) + HO3Se-(out) = zinc(in) + HCO3-(in) + HO3Se-(out). GO:0140416 transcription regulator inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140416 DNA-binding transcription factor inhibitor activity A molecular function regulator that inhibits the activity of a transcription regulator via direct binding and/or post-translational modification. GO:0140415 effector-mediated modulation of host defenses by symbiont biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140415 A process mediated by a molecule secreted by a symbiont that results in the modulation (either activation or suppresion) of a defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction. UBERON:0016399 lymph node of upper limb biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016399 A lymph node that is part of a forelimb. CHEBI:35908 glutaramate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35908 GO:0140418 effector-mediated modulation of host process by symbiont biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140418 effector mediated modulation of host process by symbiont|effector-dependent modulation of host process by symbiont|effector triggered modulation of host process by symbiont A process mediated by a molecule secreted by a symbiont that results in the modulation (either activation or suppresion) of a host structure or process. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0140417 ATP-sensitive calcium-release channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140417 Enables the transmembrane transfer of a calcium ion from intracellular stores by a channel that opens when a ATP has been bound by the channel complex or one of its constituent parts. CHEBI:35907 glutarate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35907 CHEBI:60951 flavonoid phytoalexin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60951 CHEBI:60952 diterpene phytoalexin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60952 CHEBI:60955 9(S)-HPODE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60955 CHEBI:35900 but-3-enoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35900 GO:0140410 solute:bicarbonate symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140410 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + HCO3-(out) = solute(in) + HCO3-(in). CHEBI:60954 2-hydroxy-2-methylbutanenitrile biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60954 CHEBI:60957 colneleate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60957 CHEBI:60956 colneleic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60956 CHEBI:60959 colnelenic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60959 CHEBI:84925 omega-hydroxyphytanic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84925 CHEBI:11946 4-(trimethylammonio)but-2-enoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_11946 GO:0140445 chromosome, telomeric repeat region biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140445 A complex of DNA and protein that seals the end of a chromosome. The telomeric repeat DNA consists of simple tandemly repeated sequences specific for each species. Typically one strand is G-rich and the other C-rich. The G-rich strand forms a 3'-terminal overhang, the length of which varies with species. The single strand overhang is bound by a variety of proteins, including telomere capping proteins that bind to the single-stranded DNA and seal the telomeric loop. GO:0140444 cytoskeleton-nuclear membrane anchor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140444 nuclear membrane-cytoskeleton anchor activity|cytoskeleton nuclear membrane anchor activity|cytoskeletal protein-nuclear membrane anchor activity|cytoskeletal protein-nuclear membrane adaptor activity The binding activity of a molecule that brings together a cytoskeletal protein or protein complex and a nuclear membrane lipid or membrane-associated protein, in order to maintain the localization of the cytoskeleton at a specific location of the nuclear membrane. GO:0140447 cytokine precursor processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140447 interleukin maturation|interleukin processing The cleavage of a peptide bond in a precursor form of a cytokine, resulting in the mature (active) form of the cytokine. CHEBI:11944 4-(hydroxymethyl)benzenesulfonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_11944 GO:0140446 fumigermin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140446 CHEBI:147341 fumigermin synthesis|fumigermin formation|fumigermin biosynthesis|fumigermin anabolism The chemical reactions and pathways resulting in the formation of fumigermin, an alpha-pyrone secondary metabolite found in some species of fungi such as Aspergillus fumigatus. CHEBI:84921 7-hydroxylaurate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84921 GO:0140449 centromere-nuclear envelope anchor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140449 centromere nuclear envelope tether activity|centromere nuclear envelope anchor activity|nuclear envelope-centromere tether activity|centromere-inner nuclear envelope tether activity|nuclear envelope-centromere anchor activity|centromere-inner nuclear envelope anchor activity|chromosome, centromeric region-nuclear envelope anchor activity The binding activity of a molecule that brings together the centromeric region of a chromosome and the inner nuclear membrane by interacting with both the centromere/kinetochore complex and the nuclear membrane, in order to establish and maintain the centromere/kinetochore location. GO:0140448 signaling receptor ligand precursor processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140448 signal maturation|ligand maturation The cleavage of a peptide bond in a precursor form of a signaling receptor ligand, resulting in the mature (active) form of the ligand. CHEBI:60960 colnelenate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60960 CHEBI:60962 (9S,10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60962 CHEBI:60961 (9S,10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60961 GO:0140441 protein-cysteine S-arachidonoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140441 RHEA:59748 Catalysis of the transfer of an arachidonoyl (systematic name, (5Z,8Z,11Z,14Z)-eicosatetraenoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction: in the reaction: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + L-cysteinyl-[protein] = CoA + S-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-cysteinyl-[protein]. GO:0140440 protein-cysteine S-oleoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140440 RHEA:59744 Catalysis of the transfer of an oleoyl (systematic name, (9Z)-octadecenoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction: (9Z)-octadecenoyl-CoA + L-cysteinyl-[protein] = CoA + S-(9Z-octadecenoyl)-L-cysteinyl-[protein]. CHEBI:60963 colanic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60963 GO:0140443 mitochondrion-plasma membrane adaptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140443 mitochondrion plasma membrane adaptor activity|mitochondrion plasma membrane tether activity|plasma membrane-mitochondrion adaptor activity|plasma membrane-mitochondrion tether activity The binding activity of a molecule that brings together a mitochondrion and a plasma membrane either via membrane lipid binding or by interacting with a mitochondrial outer membrane protein, to establish or maintain the localization of the mitochondrion. GO:0140442 peroxide sensor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140442 Binding to hydrogen peroxide (H2O2) and eliciting a change in the protein's activity in response to the intracellular level of that small molecule. CHEBI:60968 presilphiperfolan-8beta-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60968 CHEBI:84939 omega-hydroxy-15-methylpalmitic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84939 CHEBI:84936 ethyl octadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84936 GO:0140434 positive regulation of protein localization to meiotic spindle pole body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140434 Any process that increases the frequency, rate or extent of protein localization to a meiotic spindle pole body. CHEBI:11935 4-(beta-D-glucosyloxy)benzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_11935 GO:0140433 regulation of protein localization to meiotic spindle pole body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140433 Any process that modulates the frequency, rate or extent of protein localization to a meiotic spindle pole body. CHEBI:84934 ethyl palmitoleate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84934 CHEBI:84933 N-acetyl-D-muramoyl-L-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84933 GO:0140435 negative regulation of protein localization to meiotic spindle pole body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140435 Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to a meiotic spindle pole body. CHEBI:84932 ethyl hexadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84932 GO:0140438 protein stearoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140438 The covalent attachment of a stearoyl group to an amino acid in a protein. GO:0140439 protein-cysteine S-stearoyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140439 RHEA:59740 Catalysis of the transfer of a stearoyl (systematic name, octadecanoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction: octadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-octadecanoyl-L-cysteinyl-[protein]. CHEBI:60971 aminophospholipid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60971 CHEBI:60973 suberin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60973 GO:0140430 positive regulation of chromosome passenger complex localization to kinetochore biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140430 Any process that activates or increases the frequency, rate or extent of a chromosome passenger complex localization to kinetochore. CHEBI:60974 cyanoamino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60974 GO:0140432 5'-hydroxyl dinucleotide hydrolase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140432 Catalysis of the hydrolysis of phosphodiester bonds in 5'OH-RNA according to the reaction 5'OH-RNA + H20 = 5'OH-NpN (dinucleotide) + 5'P-RNA. CHEBI:60977 phenylalkylamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60977 GO:0140431 DNA-(abasic site) binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140431 DNA-(apurinic site) binding|DNA-(apyrimidinic site) binding|DNA AP site binding|DNA-(apurinic site/apyrimidinic site) binding Interacting selectively and non-covalently with a DNA site that has neither a purine nor a pyrimidine base. Apurinic sites can form spontaneously or when DNA glycosylase removes a damaged base. CHEBI:60979 alpha-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60979 CHEBI:60978 ketogluconate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60978 GO:0042082 GSI anchor biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042082 GSI anchor formation|GPI/GSI anchor biosynthesis|GPI/GSI anchor biosynthetic process|GSI anchor biosynthesis|GSI anchor anabolism|GSI anchor synthesis The chemical reactions and pathways resulting in the formation of a glycosylsphingolipidinositol (GSI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The sphingolipid group is linked, via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via a ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GSI anchors have variants on this canonical linkage. GO:0032717 negative regulation of interleukin-8 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032717 negative regulation of interleukin-8 biosynthetic process|downregulation of interleukin-8 production|down regulation of interleukin-8 production|negative regulation of IL-8 production|inhibition of interleukin-8 production|down-regulation of interleukin-8 production|negative regulation of interleukin-8 secretion Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-8 production. CHEBI:21374 L-prolinamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21374 GO:0042081 GSI anchor metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042081 GPI/GSI anchor metabolic process|GPI/GSI anchor metabolism|GSI anchor metabolism The chemical reactions and pathways involving glycosylsphingolipidinositol (GSI) anchors, which attach membrane proteins to the lipid bilayer of the cell membrane. GO:0032716 negative regulation of interleukin-7 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032716 negative regulation of interleukin-7 biosynthetic process|downregulation of interleukin-7 production|down regulation of interleukin-7 production|inhibition of interleukin-7 production|negative regulation of IL-7 production|down-regulation of interleukin-7 production|negative regulation of interleukin-7 secretion Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-7 production. GO:0032715 negative regulation of interleukin-6 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032715 negative regulation of interleukin-6 secretion|negative regulation of interleukin-6 biosynthetic process|downregulation of interleukin-6 production|down regulation of interleukin-6 production|negative regulation of IL-6 production|inhibition of interleukin-6 production|down-regulation of interleukin-6 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-6 production. GO:0042084 5-methyltetrahydrofolate-dependent methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042084 Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5-methyltetrahydrofolate. CHEBI:21376 rhamnonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21376 GO:0032714 negative regulation of interleukin-5 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032714 negative regulation of interleukin-5 biosynthetic process|negative regulation of interleukin-5 secretion|downregulation of interleukin-5 production|down regulation of interleukin-5 production|inhibition of interleukin-5 production|negative regulation of IL-5 production|down-regulation of interleukin-5 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-5 production. GO:0042083 5,10-methylenetetrahydrofolate-dependent methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042083 Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5,10-methylenetetrahydrofolate. GO:0032713 negative regulation of interleukin-4 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032713 downregulation of interleukin-4 production|negative regulation of interleukin-4 secretion|down regulation of interleukin-4 production|negative regulation of IL-4 production|inhibition of interleukin-4 production|down-regulation of interleukin-4 production|negative regulation of interleukin-4 biosynthetic process Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-4 production. GO:0032712 negative regulation of interleukin-3 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032712 down regulation of interleukin-3 production|inhibition of interleukin-3 production|negative regulation of IL-3 production|down-regulation of interleukin-3 production|negative regulation of interleukin-3 biosynthetic process|downregulation of interleukin-3 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-3 production. GO:0032711 negative regulation of interleukin-27 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032711 inhibition of interleukin-27 production|negative regulation of interleukin-27 biosynthetic process|negative regulation of IL-27 production|down regulation of interleukin-27 production|downregulation of interleukin-27 production|down-regulation of interleukin-27 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-27 production. GO:0042080 obsolete GPI/GSI anchor biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042080 GPI/GSI anchor biosynthesis|GPI/GSI anchor biosynthetic process|GPI/GSI anchor anabolism|GPI/GSI anchor synthesis|GPI/GSI anchor formation OBSOLETE. (Was not defined before being made obsolete). GO:0032710 negative regulation of interleukin-26 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032710 inhibition of interleukin-26 production|negative regulation of interleukin-26 biosynthetic process|negative regulation of IL-26 production|down regulation of interleukin-26 production|downregulation of interleukin-26 production|down-regulation of interleukin-26 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-26 production. GO:0042089 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042089 GO:0042086 5-methyl-5,6,7,8-tetrahydromethanopterin-dependent methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042086 Catalysis of the transfer of a methyl group to an acceptor molecule, dependent on the presence of 5-methyl-5,6,7,8-tetrahydromethanopterin. GO:0042085 5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042085 Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5-methyltetrahydropteroyltri-L-glutamate. GO:0032719 negative regulation of TRAIL production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032719 down-regulation of TRAIL production|negative regulation of TRAIL biosynthetic process|downregulation of TRAIL production|down regulation of TRAIL production|inhibition of TRAIL production Any process that stops, prevents, or reduces the frequency, rate, or extent of TRAIL production. GO:0042088 T-helper 1 type immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042088 Th1 immune response An immune response which is associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis, and which is typically orchestrated by the production of particular cytokines by T-helper 1 cells, most notably interferon-gamma, IL-2, and lymphotoxin. GO:0032718 negative regulation of interleukin-9 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032718 negative regulation of interleukin-9 biosynthetic process|downregulation of interleukin-9 production|down regulation of interleukin-9 production|inhibition of interleukin-9 production|negative regulation of IL-9 production|down-regulation of interleukin-9 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-9 production. GO:0042087 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042087 UBERON:0006960 ovary stroma biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006960 ovary stroma|stroma ovarica|stroma ovarii|interstitial tissue of ovary|stroma of the ovary|ovarian stroma The stroma of the ovary is a peculiar soft tissue, abundantly supplied with blood vessels, consisting for the most part of spindle-shaped cells with a small amount of ordinary connective tissue. These cells have been regarded by some anatomists as unstriped muscle cells, which, indeed, they most resemble; by others as connective-tissue cells. On the surface of the organ this tissue is much condensed, and forms a layer composed of short connective-tissue fibers, with fusiform cells between them. The stroma of the ovary may contain interstitial cells resembling those of the testis. CHEBI:3306 calcitonin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_3306 UBERON:0006966 coronary capillary biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006966 heart capillary A capillary that is part of the coronary system. CHEBI:59988 alpha-tyvelopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59988 UBERON:0006965 vascular cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006965 The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis[GO]. The vascular cord is composed of angioblast or vascular endothelial cells in a solid linear mass called a cord. The cord then undergoes tubulogenesis to form the lumen of the vessels[ZFA]. CHEBI:59985 beta-D-glucosyl-(1->4)-N-acetyl-D-glucosaminyl undecaprenyl diphosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59985 GO:0032706 negative regulation of interleukin-22 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032706 downregulation of interleukin-22 production|down-regulation of interleukin-22 production|inhibition of interleukin-22 production|negative regulation of interleukin-22 biosynthetic process|negative regulation of IL-22 production|down regulation of interleukin-22 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-22 production. GO:0042093 T-helper cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042093 helper T cell differentiation|T-helper cell development The process in which a relatively unspecialized thymocyte acquires specialized features of a T-helper cell. GO:0032705 negative regulation of interleukin-21 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032705 downregulation of interleukin-21 production|down-regulation of interleukin-21 production|negative regulation of interleukin-21 biosynthetic process|down regulation of interleukin-21 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-21 production. GO:0042092 type 2 immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042092 T-helper 2 type immune response|Th2 immune response An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is orchestrated by the production of particular cytokines, most notably IL-4, IL-5, IL-10, and IL-13, by any of a variety of cell types including T-helper 2 cells, eosinophils, basophils, mast cells, and nuocytes, resulting in enhanced production of certain antibody isotypes and other effects. GO:0032704 negative regulation of interleukin-20 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032704 downregulation of interleukin-20 production|down-regulation of interleukin-20 production|inhibition of interleukin-20 production|negative regulation of interleukin-20 biosynthetic process|negative regulation of IL-20 production|down regulation of interleukin-20 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-20 production. GO:0042095 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042095 GO:0032703 negative regulation of interleukin-2 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032703 down-regulation of interleukin-2 production|negative regulation of interleukin-2 biosynthetic process|downregulation of interleukin-2 production|down regulation of interleukin-2 production|negative regulation of interleukin-2 secretion|negative regulation of IL-2 production|inhibition of interleukin-2 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-2 production. GO:0042094 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042094 GO:0032702 negative regulation of interleukin-19 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032702 negative regulation of IL-19 production|down regulation of interleukin-19 production|downregulation of interleukin-19 production|down-regulation of interleukin-19 production|inhibition of interleukin-19 production|negative regulation of interleukin-19 biosynthetic process Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-19 production. GO:0032701 negative regulation of interleukin-18 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032701 negative regulation of IL-18 production|down regulation of interleukin-18 production|downregulation of interleukin-18 production|negative regulation of interleukin-18 secretion|down-regulation of interleukin-18 production|inhibition of interleukin-18 production|negative regulation of interleukin-18 biosynthetic process Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-18 production. GO:0032700 negative regulation of interleukin-17 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032700 negative regulation of IL-17 production|down regulation of interleukin-17 production|negative regulation of CTLA-8 production|downregulation of interleukin-17 production|negative regulation of interleukin-17 secretion|negative regulation of Cytotoxic T-lymphocyte-associated antigen 8 secretion|inhibition of interleukin-17 production|negative regulation of interleukin-17 biosynthetic process Any process that stops, prevents, or reduces the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines. GO:0042091 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042091 UBERON:0006948 efferent duct epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006948 epithelium of efferent ductule of testis An epithelium that is part of a efferent duct. UBERON:0006947 male genital duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006947 sperm ducts|sperm duct A duct or series of ducts that transports sperm from the gonad. In mammals this is from the seminiferous tubules through rete testis, vas efferentia, epididymis, vas deferens, ejeculatory duct to the urethra. GO:0042090 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042090 GO:0042097 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042097 GO:0042096 obsolete alpha-beta T cell receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042096 alpha-beta T cell receptor activity OBSOLETE. (Was not defined before being made obsolete). GO:0032709 negative regulation of interleukin-25 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032709 negative regulation of IL-25 production|down regulation of interleukin-25 production|downregulation of interleukin-25 production|negative regulation of interleukin-25 secretion|down-regulation of interleukin-25 production|inhibition of interleukin-25 production|negative regulation of interleukin-25 biosynthetic process Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-25 production. GO:0032708 negative regulation of interleukin-24 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032708 negative regulation of IL-24 production|down regulation of interleukin-24 production|downregulation of interleukin-24 production|down-regulation of interleukin-24 production|inhibition of interleukin-24 production|negative regulation of interleukin-24 biosynthetic process Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-24 production. GO:0042099 obsolete gamma-delta T cell receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042099 gamma-delta T cell receptor activity OBSOLETE. (Was not defined before being made obsolete). GO:0032707 negative regulation of interleukin-23 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032707 down regulation of interleukin-23 production|downregulation of interleukin-23 production|down-regulation of interleukin-23 production|inhibition of interleukin-23 production|negative regulation of interleukin-23 biosynthetic process|negative regulation of IL-23 production Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-23 production. GO:0042098 T cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042098 T lymphocyte proliferation|T-cell proliferation|T-lymphocyte proliferation The expansion of a T cell population by cell division. Follows T cell activation. CHEBI:59971 GDP-D-glycero-alpha-D-manno-heptose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59971 UBERON:0006957 submandibular gland primordium epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006957 submaxillary gland primordium epithelium An epithelium that is part of a submandibular gland primordium. CHEBI:59979 3',5'-di-O-methyltricetin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59979 UBERON:0006955 uterine epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006955 uterus epithelium An epithelium that is part of a uterus. CHEBI:59976 3'-O-methyltricetin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59976 UBERON:0006953 ejaculatory duct epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006953 The ejaculatory duct epithelium is composed of cuboidal to columnar cells between or through which project the terminal parts of the ducts of the unicellular prostate glands. UBERON:0006938 pinna surface epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006938 An epithelium that is part of a pinna. UBERON:0006937 inner ear epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006937 the epithelial cell layer containing the sensory hair cells and their associated sensory nerve terminals UBERON:0006936 thymus subcapsular epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006936 the epithelial cells lining the capsule and trabeculae of the thymus CHEBI:59969 GDP-D-glycero-alpha-D-manno-heptose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59969 CHEBI:35992 penams biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35992 CHEBI:35998 tridecane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35998 UBERON:0006946 efferent duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006946 seminal duct|vasa efferentia|efferent ductule|ductuli efferentes testis The efferent ducts (or efferent ductules or ductuli efferentes) connect the rete testis with the initial section of the epididymis. The ductuli are unilaminar and composed of columnar ciliated and non-ciliated (absorptive) cells. The ciliated cells serve to stir the luminal fluids, possibly to help ensure homogeneous absorption of water from the fluid produced by the testis, which results in an increase in the concentration of luminal sperm. The epithelium is surrounded by a band of smooth muscle that helps to propel the sperm toward the epididymis. CHEBI:59967 ADP-D-glycero-beta-D-manno-heptose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59967 CHEBI:59966 ADP-D-glycero-beta-D-manno-heptose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59966 CHEBI:59964 imidazolium ion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59964 CHEBI:35990 bridged compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35990 CHEBI:59961 alpha-selinene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59961 CHEBI:21363 L-methionine sulfone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21363 UBERON:0006929 glandular columnar epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006929 Simple columnar epithelium that constitutes the secretory part of a gland. Examples: epithelium of stomach, luminal epithelium of lactiferous duct.[FMA] CHEBI:59959 (3R,6E)-nerolidol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59959 CHEBI:21368 L-ornithine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21368 CHEBI:59958 (3S,6E)-nerolidol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59958 UBERON:0006925 digestive system gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006925 digestive gland Any gland that is part of the digestive system. CHEBI:59957 D-glycero-D-manno-heptose 1,7-bisphosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59957 UBERON:0006934 sensory epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006934 neuroepithelium Simple columnar epithelium made up of cells specialized to serve as sensory cells for the reception of external stimuli, as the sensory cells of the cochlea, vestibule, nasal mucosa, and tongue. CHEBI:59955 D-glycero-D-manno-heptose 7-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59955 UBERON:0006932 vestibular epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006932 inner ear vestibular component epithelium|epithelium of vestibular labyrinth|vestibular sensory epithelium An epithelium that is part of a vestibular labyrinth. CHEBI:59953 thebaine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59953 UBERON:0006931 stomach glandular region mucosa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006931 stomach glandular region glandular mucous membrane stomach mucosa that is lined with glandular epithelium and part of a stomach glandular region. UBERON:0006930 glandular cuboidal epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006930 CHEBI:59950 neopinone(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59950 CHEBI:21332 L-idarate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_21332 CHEBI:21333 L-idaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21333 CHEBI:21336 L-idonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21336 CHEBI:59948 columbianetin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59948 CHEBI:59947 (S)-2-ureidoglycine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59947 CHEBI:35979 dioxo monocarboxylic acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35979 CHEBI:35971 6-hydroxy monocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35971 CHEBI:35970 4-hydroxy monocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35970 CHEBI:35973 3-oxo monocarboxylic acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35973 CHEBI:3347 candesartan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_3347 CHEBI:35972 dihydroxy monocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35972 CHEBI:3349 candicidin D biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_3349 CHEBI:35975 5-oxo monocarboxylic acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35975 CHEBI:35974 4-oxo monocarboxylic acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35974 CHEBI:35976 6-oxo monocarboxylic acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35976 CHEBI:21337 idonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21337 CHEBI:59945 (S)-2-ureidoglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59945 GO:0140499 negative regulation of mitotic spindle assembly checkpoint signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140499 Any process that stops, prevents, or reduces the frequency, rate or extent of negative regulation of mitotic spindle assembly checkpoint signaling. GO:0140494 migrasome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140494 A vesicular organelle that forms on retraction fibers behind migrating cells and mediates the release of cytoplasmic contents during cell migration. CHEBI:35984 7-oxo monocarboxylic acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35984 GO:0140493 very long-chain fatty acid beta-oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140493 A fatty acid beta-oxidation pathway acting on fatty acid which has a chain length greater than C22 in which the initial step, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA oxidase; the electrons removed by oxidation pass directly to oxygen and produce hydrogen peroxide, which is cleaved by peroxisomal catalases. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively). CHEBI:35983 7-oxo monocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35983 CHEBI:35986 nonan-1-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35986 GO:0140496 gamma-tubulin complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140496 Interacting selectively and non-covalently with a gamma-tubulin complex. GO:0140495 migracytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140495 A cell migration-dependent mechanism for releasing cellular contents. CHEBI:3359 cannabidiolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_3359 GO:0140498 mannan polymerase I complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140498 A complex with alpha-(1->6)-mannosyltransferase activity, located in the cis Golgi membrane; adds mannan to N-linked glycans on proteins as part of the priming and elongation of alpha 1,6-linked Man backbone. In S. cerevisiae, contains Mnn9p and Van1p. GO:0140497 mannan polymerase II complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140497 A complex with alpha-(1->6)-mannosyltransferase activity, located in the cis Golgi membrane; adds mannan to N-linked glycans on proteins as part of the elongation of alpha 1,6-linked Man backbone. In S. cerevisiae, contains Mnn9p, Anp1p, Mnn10p, Mnn11p, and Hoc1p. CHEBI:35987 diamino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35987 CHEBI:59930 N-formylmaleamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59930 GO:0140490 microtubule nucleator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140490 microtubule nucleation template activity The action of a molecule that provides a shape mimicking the end of a microtubule to seed the formation of a new microtubule via self-assembly. CHEBI:21314 glutamyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21314 CHEBI:35958 epsilon-amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35958 CHEBI:35951 dioxo monocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35951 CHEBI:35950 4-oxo monocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35950 CHEBI:35952 5-oxo monocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35952 CHEBI:59924 5,6,7,8-tetrahydrosarcinapterin(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59924 CHEBI:59923 coenzyme alpha-F420-3(6-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59923 CHEBI:59922 N-acetyl-beta-D-glucosaminyl-(1->4)-D-glucosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59922 CHEBI:59920 coenzyme F420-1(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59920 UBERON:0006984 anatomical surface biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006984 A two dimensional anatomical structure that is the boundary between an anatomical structure and an anatomical substance, an anatomical space or the organism's environment. Examples include the surface of your skin, the surface of the lining of your gut; the surface of the endothelium of you aorta that is in contact with blood.n CHEBI:59918 acyl monophosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59918 CHEBI:59917 4-O-phosphohygromycin B(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59917 CHEBI:59916 methylmalonyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59916 CHEBI:59914 thio fatty acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59914 CHEBI:35969 3-hydroxy monocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35969 CHEBI:35960 6-oxo monocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35960 CHEBI:35962 sorbic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35962 CHEBI:35964 penta-2,4-dienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35964 CHEBI:59913 thio-fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59913 CHEBI:59911 N-formylmaleamate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59911 CHEBI:59910 N-acetyl-beta-D-glucosaminyl-(1->4)-D-glucosaminium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59910 OBA:0000099 membrane potential biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000099 electric potential of membrane The electric potential of a membrane. OBA:0000098 membrane lipid distribution biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000098 membrane lipid spatial pattern The spatial pattern of a lipid when measured in membrane. OBA:0000093 mRNA stability biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000093 macromolecular stability of mRNA The macromolecular stability of a mRNA. OBA:0000092 lysosomal membrane permeability biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000092 permeability of lysosomal membrane The permeability of a lysosomal membrane. GO:0042244 spore wall assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042244 spore wall formation|spore coat biosynthetic process|spore coat biosynthesis The aggregation, arrangement and bonding together of a set of components to form a spore wall; a spore wall is the specialized envelope lying outside the cell membrane of a spore. GO:0042243 asexual spore wall assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042243 asexual spore wall formation The aggregation, arrangement and bonding together of a set of components to form an asexual spore wall, the specialized envelope lying outside the cell membrane of a spore derived from an asexual process. Examples of this process are found in Bacterial and Fungal species. GO:0042246 tissue regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042246 The regrowth of lost or destroyed tissues. OBA:0000091 lysosomal lumen pH biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000091 The acidity when measured in lysosomal lumen. OBA:0000090 lung blood pressure biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000090 lung blood pressure The pressure of a blood when measured in lung. GO:0042245 RNA repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042245 Any process that results in the repair of damaged RNA. GO:0042240 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042240 GO:0042242 cobyrinic acid a,c-diamide synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042242 EC:6.3.5.11|RHEA:26289 cobyrinate a,c-diamide synthase activity|cobyrinate a c diamide synthase activity|CobB|cobyrinate a,c diamide synthase activity|cobyrinate a c-diamide synthase activity Catalysis of the conversion of cobyrinic acid to cobyrinic acid a,c-diamide via the intermediate formation of cobyrinic acid c-monoamide. GO:0042241 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042241 GO:0042248 maintenance of polarity of follicular epithelium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042248 The maintenance of an established polarized follicular epithelial sheet. GO:0042247 establishment of planar polarity of follicular epithelium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042247 Coordinated organization of groups of cells in the plane of a follicular epithelium, such that they all orient to similar coordinates. GO:0042249 establishment of planar polarity of embryonic epithelium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042249 Coordinated organization of groups of cells in the plane of an embryonic epithelium, such that they all orient to similar coordinates. PATO:0000001 quality biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PATO_0000001 A dependent entity that inheres in a bearer by virtue of how the bearer is related to other entities OBA:0000088 liquid surface tension biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000088 surface tension of liquid configuration The surface tension of a liquid configuration. OBA:0000084 imaginal disc-derived wing size biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000084 size of imaginal disc-derived wing The size of a imaginal disc-derived wing. GO:0042255 ribosome assembly biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0042255 ribosomal subunit assembly The aggregation, arrangement and bonding together of the mature ribosome and of its subunits. GO:0042254 ribosome biogenesis biolink:BiologicalProcess go-plus goslim_pir|goslim_drosophila|goslim_aspergillus|goslim_generic|goslim_pombe|goslim_chembl|goslim_candida http://purl.obolibrary.org/obo/GO_0042254 ribosome biogenesis and assembly A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis. GO:0042257 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042257 GO:0042256 mature ribosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042256 The aggregation, arrangement and bonding together of the large and small ribosomal subunits into a functional ribosome. GO:0042251 maintenance of polarity of larval imaginal disc epithelium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042251 The maintenance of an established polarized larval imaginal disc epithelium. GO:0042250 maintenance of polarity of embryonic epithelium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042250 The maintenance of an established polarized embryonic epithelial sheet. GO:0042253 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042253 GO:0042252 establishment of planar polarity of larval imaginal disc epithelium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042252 Coordinated organization of groups of cells in the plane of a larval imaginal disc epithelium, such that they all orient to similar coordinates. GO:0042259 peptidyl-L-beta-methylthioasparagine biosynthetic process from peptidyl-asparagine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042259 RESID:AA0320 peptidyl-L-beta-methylthioasparagine anabolism from peptidyl-asparagine|peptidyl-L-beta-methylthioasparagine formation from peptidyl-asparagine|peptidyl-L-beta-methylthioasparagine synthesis from peptidyl-asparagine The modification of peptidyl-asparagine to form peptidyl-L-beta-methylthioasparagine, typical of bacterial ribosomal protein S12. GO:0042258 molybdenum incorporation via L-serinyl molybdopterin guanine dinucleotide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042258 RESID:AA0319 The incorporation of molybdenum into a protein via L-serinyl molybdopterin guanine dinucleotide. OBA:0000089 long-term neuronal synaptic plasticity biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000089 OBA:0000074 heart contraction rate biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000074 rate of heart contraction The rate of a heart contraction. GO:0042260 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042260 GO:0032899 regulation of neurotrophin production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032899 Any process that modulates the frequency, rate, or extent of production of a neurotrophin. GO:0032898 neurotrophin production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032898 The appearance of a neurotrophin due to biosynthesis or secretion by cells in a neuron's target field, resulting in an increase in its intracellular or extracellular levels. A neurotrophin is any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth. GO:0032897 negative regulation of viral transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032897 down-regulation of viral transcription|inhibition of viral transcription|down regulation of viral transcription|downregulation of viral transcription Any process that stops, prevents, or reduces the frequency, rate or extent of viral transcription. OBA:0000072 follicle cell microvillus length biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000072 microvillus length of follicle cell The microvillus length of a follicle cell. GO:0042266 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042266 GO:0042265 peptidyl-asparagine hydroxylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042265 peptidyl-aspartic acid/asparagine hydroxylation The hydroxylation of peptidyl-asparagine to form peptidyl-hydroxyasparagine. GO:0042268 regulation of cytolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042268 Any process that modulates the frequency, rate or extent of the rupture of cell membranes and the loss of cytoplasm. GO:0042267 natural killer cell mediated cytotoxicity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042267 natural killer cell mediated cell killing|NK cell mediated cell death|natural killer cell mediated cytolysis|natural killer cell mediated cell death|NK cell mediated cytolysis|killer activity|NK cell mediated cytotoxicity|natural killer-cell mediated cytolysis|NK cell mediated cell killing The directed killing of a target cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors. GO:0042262 DNA protection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042262 Any process in which DNA is protected from damage by, for example, oxidative stress. GO:0042261 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042261 GO:0042264 peptidyl-aspartic acid hydroxylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042264 peptidyl-aspartic acid/asparagine hydroxylation The hydroxylation of peptidyl-aspartic acid to form peptidyl-hydroxyaspartic acid. GO:0042263 neuropeptide F receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042263 NPF receptor activity Combining with neuropeptide F and transmitting the signal within the cell to initiate a change in cell activity. Neuropeptide F is an arthropod peptide of more than 28 residues (typically 28-45) with a consensus C-terminal RxRFamide (commonly RPRFa, but also RVRFa. CHEBI:137599 long-chain 3-oxo-fatty acyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137599 GO:0042269 regulation of natural killer cell mediated cytotoxicity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042269 regulation of NK cell mediated cell death|regulation of NK cell mediated cytolysis|regulation of natural killer cell mediated cell death|regulation of natural killer-cell mediated cytolysis|regulation of NK cell mediated cell killing|regulation of NK cell mediated cytotoxicity|regulation of natural killer cell mediated cell killing|regulation of natural killer cell mediated cytolysis Any process that modulates the frequency, rate, or extent of natural killer cell mediated cytotoxicity. GO:0032896 palmitoyl-CoA 9-desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032896 palmitoyl-CoA delta9-desaturase acitivity Catalysis of the reaction: palmitoyl-CoA + AH2 + O2 = palmitoleic acid (16:1delta9) + A + 2 H2O. CHEBI:137594 N-acetyl-alpha-D-muramate 1-phosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137594 CHEBI:137593 (2E,4Z)-deca-2,4-dienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137593 GO:0032895 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032895 GO:0032894 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032894 GO:0032893 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032893 CHEBI:137598 4-aminosalicylate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137598 GO:0032892 positive regulation of organic acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032892 up regulation of organic acid transport|upregulation of organic acid transport|stimulation of organic acid transport|up-regulation of organic acid transport|activation of organic acid transport Any process that activates or increases the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. OBA:0000079 hormone levels biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000079 amount of hormone The amount of a hormone. GO:0032891 negative regulation of organic acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032891 down-regulation of organic acid transport|downregulation of organic acid transport|down regulation of organic acid transport|inhibition of organic acid transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0032890 regulation of organic acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032890 Any process that modulates the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0042271 susceptibility to natural killer cell mediated cytotoxicity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042271 susceptibility to NK cell mediated cytotoxicity|susceptibility to NK cell mediated cell killing|susceptibility to natural killer cell mediated cell killing|susceptibility to NK cell mediated cell death|susceptibility to NK cell mediated cytolysis|susceptibility to natural killer cell mediated cytolysis|susceptibility to natural killer cell mediated cell death The process of causing a cell to become susceptible to natural killer cell mediated cytotoxicity. OBA:0000066 direction of cell growth biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000066 direction of cell growth The direction of a cell growth. GO:0042270 protection from natural killer cell mediated cytotoxicity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042270 protection from NK cell mediated cell death|protection from natural killer cell mediated cell death|protection from natural killer cell mediated cytolysis|protection from NK cell mediated cytolysis|protection from NK cell mediated cytotoxicity|protection from NK cell mediated cell killing|protection from natural killer cell mediated cell killing The process of protecting a cell from natural killer cell mediated cytotoxicity. GO:0032889 regulation of vacuole fusion, non-autophagic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032889 Any process that modulates the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole. GO:0032888 regulation of mitotic spindle elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032888 Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle. GO:0032887 regulation of spindle elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032887 Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the spindle. GO:0032886 regulation of microtubule-based process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032886 Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton. OBA:0000061 circulating fibrinogen levels biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000061 amount of fibrinogen complex The amount of a fibrinogen complex. GO:0042277 peptide binding biolink:MolecularActivity go-plus goslim_chembl|goslim_pir http://purl.obolibrary.org/obo/GO_0042277 Interacting selectively and non-covalently with peptides, any of a group of organic compounds comprising two or more amino acids linked by peptide bonds. GO:0042276 error-prone translesion synthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042276 mutagenic PRR|mutagenic postreplication DNA repair|error-prone postreplication DNA repair The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions and causes an increase in the endogenous mutation level. For example, in E. coli, a low fidelity DNA polymerase, pol V, copies lesions that block replication fork progress. This produces mutations specifically targeted to DNA template damage sites, but it can also produce mutations at undamaged sites. GO:0042279 nitrite reductase (cytochrome, ammonia-forming) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042279 EC:1.7.2.2|Wikipedia:Cytochrome_c_nitrite_reductase|MetaCyc:1.7.2.2-RXN|RHEA:13089 multiheme nitrite reductase activity|cytochrome c nitrite reductase activity|nitrite reductase (cytochrome; ammonia-forming)|cytochrome c552 activity|ammonia:ferricytochrome-c oxidoreductase activity Catalysis of the reaction: NH3 + 2 H2O + 6 ferricytochrome c = nitrite + 6 ferrocytochrome c + 7 H+. GO:0042278 purine nucleoside metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042278 purine nucleoside metabolism|purine metabolic process|purine metabolism The chemical reactions and pathways involving one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside). GO:0042273 ribosomal large subunit biogenesis biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0042273 ribosomal large subunit biogenesis and assembly A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a large ribosomal subunit; includes transport to the sites of protein synthesis. GO:0042272 nuclear RNA export factor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042272 Mex67-Mtr2 complex|TAP-p15 complex|NXF1-NXT1 complex A protein complex that contains two proteins (know in several organisms, including Drosophila, as NXF1 and NXF2) and is required for the export of the majority of mRNAs from the nucleus to the cytoplasm; localized in the nucleoplasm and at both the nucleoplasmic and cytoplasmic faces of the nuclear pore complex; shuttles between the nucleus and the cytoplasm. GO:0042275 error-free postreplication DNA repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042275 error-free PRR|error-free replication restart The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA via processes such as template switching, which does not remove the replication-blocking lesions but does not increase the endogenous mutation rate. GO:0042274 ribosomal small subunit biogenesis biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0042274 ribosomal small subunit biogenesis and assembly A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a small ribosomal subunit; includes transport to the sites of protein synthesis. GO:0032885 regulation of polysaccharide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032885 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides. GO:0032884 regulation of cell wall chitin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032884 regulation of cell wall chitin biosynthesis|regulation of cell wall chitin anabolism|regulation of cell wall chitin synthesis|regulation of cell wall chitin formation Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cell wall chitin. GO:0032883 regulation of chitin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032883 regulation of chitin biosynthesis|regulation of chitin anabolism|regulation of chitin synthesis|regulation of chitin formation Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chitin. GO:0032882 regulation of chitin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032882 regulation of chitin metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chitin. GO:0032881 regulation of polysaccharide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032881 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving polysaccharides. OBA:0000068 endosome size biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000068 size of endosome The size of a endosome. GO:0032880 regulation of protein localization biolink:BiologicalProcess go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localisation Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location. OBA:0000067 embryonic cell shape biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000067 shape of embryonic cell The shape of a embryonic cell. GO:0042280 obsolete cell surface antigen activity, host-interacting biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042280 cell surface antigen activity, host-interacting OBSOLETE. Functions as an immunogenic target for the host immune system that masks other invariant surface molecules from immune recognition. GO:0042282 hydroxymethylglutaryl-CoA reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042282 RHEA:14833|KEGG_REACTION:R02081|MetaCyc:HYDROXYMETHYLGLUTARYL-COA-REDUCTASE-RXN|EC:1.1.1.88 beta-hydroxy-beta-methylglutaryl CoA-reductase activity|hydroxymethylglutaryl coenzyme A reductase activity|beta-hydroxy-beta-methylglutaryl coenzyme A reductase activity|3-hydroxy-3-methylglutaryl-coenzyme A reductase activity|(R)-mevalonate:NAD+ oxidoreductase (CoA-acylating)|hydroxymethylglutaryl-CoA reductase (NADH) activity|HMG-CoA reductase activity|3-hydroxy-3-methylglutaryl coenzyme A reductase activity Catalysis of the reaction: (R)-mevalonate + CoA + 2 NAD(+) = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADH. GO:0042281 dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042281 MetaCyc:RXN-5470|EC:2.4.1.267|RHEA:30635 dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase activity Catalysis of the addition of the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol. GO:0032879 regulation of localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032879 regulation of localisation Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location. GO:0032878 regulation of establishment or maintenance of cell polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032878 Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns. GO:0032877 positive regulation of DNA endoreduplication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032877 stimulation of DNA endoreduplication|up-regulation of DNA endoreduplication|positive regulation of DNA re-duplication|positive regulation of DNA endoreplication|upregulation of DNA endoreduplication|up regulation of DNA endoreduplication|activation of DNA endoreduplication Any process that activates or increases the frequency, rate or extent of DNA endoreduplication. GO:0032876 negative regulation of DNA endoreduplication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032876 down-regulation of DNA endoreduplication|negative regulation of DNA re-duplication|inhibition of DNA endoreduplication|negative regulation of DNA endoreplication|down regulation of DNA endoreduplication|downregulation of DNA endoreduplication Any process that stops, prevents, or reduces the frequency, rate or extent of DNA endoreduplication. GO:0032875 regulation of DNA endoreduplication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032875 regulation of DNA endoreplication|regulation of DNA re-duplication Any process that modulates the frequency, rate or extent of DNA endoreduplication. GO:0042288 MHC class I protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042288 gamma-delta T cell receptor activity|major histocompatibility complex class I binding|alpha-beta T cell receptor activity|T cell receptor activity|major histocompatibility complex class I ligand Interacting selectively and non-covalently with major histocompatibility complex class I molecules; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation. GO:0042287 MHC protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042287 major histocompatibility complex binding|major histocompatibility complex ligand Interacting selectively and non-covalently with major histocompatibility complex molecules; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation. GO:0042289 MHC class II protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042289 major histocompatibility complex class II binding|major histocompatibility complex class II ligand Interacting selectively and non-covalently with major histocompatibility complex class II molecules; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation. GO:0042284 sphingolipid delta-4 desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042284 Reactome:R-HSA-428259 delta-4 sphingolipid desaturase activity Catalysis of the introduction of a trans double bond between C4 and C5 of the long chain base region of a sphingolipid. Sphingolipids are composed of a long chain base (LCB) amide-linked to a very long chain fatty acid. GO:0042283 dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042283 MetaCyc:RXN-5471|EC:2.4.1.265|RHEA:31307 dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase activity Catalysis of the addition of the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol. GO:0042286 glutamate-1-semialdehyde 2,1-aminomutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042286 EC:5.4.3.8|MetaCyc:GSAAMINOTRANS-RXN|RHEA:14265|KEGG_REACTION:R02272 (S)-4-amino-5-oxopentanoate 4,5-aminomutase activity|glutamate-1-semialdehyde aminotransferase activity Catalysis of the reaction: (S)-4-amino-5-oxopentanoate = 5-aminolevulinate. GO:0042285 xylosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042285 Catalysis of the transfer of a xylosyl group to an acceptor molecule, typically another carbohydrate or a lipid. GO:0032874 positive regulation of stress-activated MAPK cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032874 positive regulation of stress-activated MAPKKK signaling pathway|positive regulation of stress-activated MAPK signaling pathway|upregulation of stress-activated MAPK cascade|up regulation of stress-activated MAPK cascade|activation of stress-activated MAPK cascade|positive regulation of stress-activated MAPKKK cascade|stimulation of stress-activated MAPK cascade|positive regulation of p38 MAPK signaling|positive regulation of stress-activated MAPK signalling pathway|positive regulation of stress-activated MAPKKK signalling pathway|positive regulation of p38 MAPK signalling|up-regulation of stress-activated MAPK cascade Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade. CHEBI:137572 Cer(d41:1) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137572 GO:0032873 negative regulation of stress-activated MAPK cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032873 negative regulation of stress-activated MAPK signaling pathway|negative regulation of stress-activated MAPKKK signaling pathway|down regulation of stress-activated MAPK cascade|downregulation of stress-activated MAPK cascade|negative regulation of p38 MAPK signaling|negative regulation of stress-activated MAPKKK signalling pathway|negative regulation of stress-activated MAPK signalling pathway|negative regulation of stress-activated MAPKKK cascade|down-regulation of stress-activated MAPK cascade|inhibition of stress-activated MAPK cascade|negative regulation of p38 MAPK signalling Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade. CHEBI:137570 Cer(d38:1) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137570 GO:0032872 regulation of stress-activated MAPK cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032872 regulation of stress-activated MAPKKK cascade|regulation of p38 MAPK signalling|regulation of stress-activated MAPKKK signaling pathway|regulation of stress-activated MAPK signaling pathway|regulation of p38 MAPK signaling|regulation of stress-activated MAPKKK signalling pathway|regulation of stress-activated MAPK signalling pathway Any process that modulates the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade. GO:0032871 regulation of karyogamy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032871 Any process that modulates the frequency, rate or extent of karyogamy, the creation of a single nucleus from multiple nuclei as a result of membrane fusion. GO:0032870 cellular response to hormone stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032870 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus. CHEBI:137574 Cer(d44:0) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137574 GO:0042291 obsolete Hub1 hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042291 Hub1 hydrolase activity OBSOLETE. (Was not defined before being made obsolete). GO:0042290 obsolete URM1 hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042290 URM1 hydrolase activity OBSOLETE. (Was not defined before being made obsolete). GO:0042293 Hub1 activating enzyme activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042293 Catalysis of the activation of the small ubiquitin-related modifier Hub1, through the formation of an ATP-dependent high-energy thiolester bond. GO:0032869 cellular response to insulin stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032869 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms. GO:0032868 response to insulin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032868 response to insulin stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms. GO:0042292 URM1 activating enzyme activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042292 Catalysis of the activation of the small ubiquitin-related modifier URM1, through the formation of an ATP-dependent high-energy thiolester bond. GO:0032867 L-arabinose:NADP reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032867 MetaCyc:RXN-8772|RHEA:25229|SABIO-RK:1858|KEGG_REACTION:R01759 arabinose reductase activity|arabinose:NADP reductase activity Catalysis of the reaction: L-arabitol + NADP+ = L-arabinose + NADPH + H+. GO:0032866 D-xylose:NADP reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032866 MetaCyc:RXN-8773|RHEA:27445 xylose reductase activity|D-xylose reductase activity Catalysis of the reaction: D-xylitol + NADP+ = D-xylose + NADPH + H+. GO:0032865 ERMES complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032865 mitochore|ER-mitochondria encounter structure|Mdm10/Mdm12/Mmm1 complex|MMM1 complex A protein complex that links the endoplasmic reticulum with mitochondria and may have a role in promoting exchange of calcium and phospholipids between the two organelles. GO:0032864 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032864 GO:0042299 lupeol synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042299 MetaCyc:RXN-111|EC:5.4.99.-|RHEA:31383 oxidosqualene:lupeol cyclase activity Catalysis of the reaction: (S)-2,3-epoxysqualene = lupeol. This reaction is the cyclization of (S)-2,3-epoxysqualene (2,3-oxidosqualene) to lupeol. GO:0042298 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042298 GO:0042295 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042295 GO:0042294 URM1 transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042294 Catalysis of the transfer of URM1 from one protein to another via the reaction X-URM1 + Y --> Y-URM1 + X, where both X-URM1 and Y-URM1 are covalent linkages. GO:0042297 vocal learning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042297 Wikipedia:Vocal_learning A behavioral process whose outcome is a relatively long-lasting behavioral change whereby an organism modifies innate vocalizations to imitate sounds produced by others. GO:0042296 ISG15 transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042296 Reactome:R-HSA-5653754 ISG15 conjugating enzyme activity Catalysis of the transfer of ISG15 from one protein to another via the reaction X-ISG15 + Y --> Y-ISG15 + X, where both X-ISG15 and Y-ISG15 are covalent linkages. GO:0032863 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032863 CHEBI:137583 2-[(15R)-hydroxy-(5Z,8Z,11Z,13E)-icosatetraenoyl]-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137583 GO:0032862 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032862 CHEBI:137582 2-[(11R)-hydroxy-(5Z,8Z,12E,14Z)-icosatetraenoyl]-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137582 GO:0032861 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032861 CHEBI:137581 2-[(5Z,13E,15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dien-1-oyl]-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137581 GO:0032860 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032860 CHEBI:137580 2-[(11R)-hydroxy-(5Z,8Z,12E,14Z)-icosatetraenoyl]-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137580 CHEBI:137586 alkyl,acylglyceride biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137586 CHEBI:137585 2-[(5Z,13E,15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dien-1-oyl]-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137585 CHEBI:137584 2-[(15S)-hydroxy-(5Z,8Z,11Z,13E)-icosatetraenoyl]-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137584 GO:0032859 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032859 GO:0032858 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032858 GO:0032857 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032857 GO:0032856 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032856 GO:0032855 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032855 GO:0032854 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032854 GO:0032853 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032853 CHEBI:137558 2-O-[alpha-D-glucosyl-(1->6)-alpha-D-glucosyl]-D-glyceric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137558 CHEBI:137550 N-(fatty acyl)-L-alpha-amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137550 GO:0032852 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032852 GO:0032851 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032851 GO:0032850 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032850 CHEBI:3163 bracteatin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_3163 CHEBI:3165 bradykinin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_3165 CHEBI:137553 2-O-[6-O-octanoyl-alpha-D-glucosyl-(1->6)-alpha-D-glucosyl]-D-glyceric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137553 GO:0032849 positive regulation of cellular pH reduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032849 positive regulation of reduction of pH in cell|upregulation of cellular pH reduction|positive regulation of cell pH reduction|positive regulation of reduction of cellular pH|positive regulation of intracellular acidification|up regulation of cellular pH reduction|activation of cellular pH reduction|positive regulation of cellular acidification|stimulation of cellular pH reduction|positive regulation of intracellular pH reduction|up-regulation of cellular pH reduction Any process that activates or increases the frequency, rate, or extent of a process that reduces the internal pH of a cell. GO:0032848 negative regulation of cellular pH reduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032848 negative regulation of reduction of pH in cell|down regulation of cellular pH reduction|negative regulation of reduction of cellular pH|downregulation of cellular pH reduction|negative regulation of cell pH reduction|negative regulation of cellular acidification|negative regulation of intracellular acidification|down-regulation of cellular pH reduction|negative regulation of intracellular pH reduction|inhibition of cellular pH reduction Any process that stops, prevents, or reduces the frequency, rate, or extent of a process that reduces the internal pH of a cell. GO:0032847 regulation of cellular pH reduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032847 regulation of cell pH reduction|regulation of intracellular pH reduction|regulation of intracellular acidification|regulation of reduction of cellular pH|regulation of reduction of pH in cell|regulation of cellular acidification Any process that modulates the frequency, rate, or extent of a process that reduces the internal pH of a cell. GO:0032846 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032846 GO:0032845 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032845 GO:0032844 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032844 GO:0032843 hydroperoxide reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032843 Catalysis of the reaction: 2 RSH + ROOH = RSSR + ROH + H2O. This reaction is the thiol-dependent conversion of an organic hydroperoxide to the corresponding alcohol. GO:0032842 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032842 CHEBI:137569 Cer(d34:1) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137569 CHEBI:3179 bromobenzene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_3179 CHEBI:137568 Cer(d34:0) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137568 CHEBI:137567 11(S)-HETE(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137567 CHEBI:137566 EC 2.5.1.48 (cystathionine gamma-synthase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137566 GO:0032841 calcitonin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032841 Interacting selectively and non-covalently with calcitonin, a peptide hormone responsible for reducing serum calcium levels by inhibiting osteoclastic bone reabsorption and promoting renal calcium excretion. It is synthesized and released by the C cells of the thyroid. GO:0032840 intramolecular proline-rich ligand binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032840 intramolecular proline-rich region binding Interacting selectively and non-covalently with a proline-rich region within the same polypeptide. CHEBI:137565 (3E,7E)-dolabella-3,7-dien-18-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137565 CHEBI:137564 (+)-(1(10)E,4E,6S,7R)-germacradien-6-ol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137564 CHEBI:137563 (1R,4R,5S)-(-)-guaia-6,10(14)-diene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137563 CHEBI:137562 (+)-eremophilene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137562 OBO:GOCHE_48705 substance with agonist role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_48705 CHEBI:80489 desmethylxanthohumol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_80489 GO:0042200 cyanuric acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042200 UM-BBD_pathwayID:cya cyanuric acid catabolism|cyanuric acid degradation|cyanuric acid breakdown The chemical reactions and pathways resulting in the breakdown of cyanuric acid, a potential degradation product of triazine herbicides. GO:0042202 N-cyclopropylmelamine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042202 UM-BBD_pathwayID:cpm N-cyclopropylmelamine degradation|cyromazine catabolic process|N-cyclopropylmelamine catabolism|N-cyclopropylmelamine breakdown|cyromazine catabolism The chemical reactions and pathways resulting in the breakdown of N-cyclopropylmelamine, a triazine compound commonly used as an insecticide. GO:0042201 N-cyclopropylmelamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042201 cyromazine metabolism|cyromazine metabolic process|N-cyclopropylmelamine metabolism The chemical reactions and pathways involving N-cyclopropylmelamine, a triazine compound commonly used as an insect growth regulator insecticide. GO:0042208 propylene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042208 UM-BBD_pathwayID:pro propylene degradation|propylene catabolism|propylene breakdown The chemical reactions and pathways resulting in the breakdown of propylene, an alkene produced by catalytic or thermal cracking of hydrocarbons or as a by-product of petroleum refining. GO:0042207 styrene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042207 UM-BBD_pathwayID:sty styrene breakdown|styrene catabolism|styrene degradation The chemical reactions and pathways resulting in the breakdown of styrene, an aromatic hydrocarbon liquid used in the manufacture of polystyrene. GO:0042209 orcinol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042209 UM-BBD_pathwayID:orc orcinol breakdown|orcin catabolic process|orcinol catabolism|orcin catabolism|orcinol degradation The chemical reactions and pathways resulting in the breakdown of orcinol (5-methyl-1,3-benzenediol), an aromatic compound derived from the fermentation of lichen and synthesized by some higher plants. GO:0042204 s-triazine compound catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042204 UM-BBD_pathwayID:tria s-triazine compound degradation|s-triazine compound catabolism|s-triazine compound breakdown The chemical reactions and pathways resulting in the breakdown of any s-triazine compound. These compounds include many pesticides of widespread use in agriculture, and are characterized by a symmetrical hexameric ring consisting of alternating carbon and nitrogen atoms. GO:0042203 toluene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042203 toluene degradation|toluene breakdown|toluene catabolism The chemical reactions and pathways resulting in the breakdown of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products. GO:0042206 halogenated hydrocarbon catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042206 halogenated hydrocarbon catabolism|halogenated hydrocarbon degradation|halogenated hydrocarbon breakdown The chemical reactions and pathways resulting in the breakdown of halogenated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with halogen atoms. GO:0042205 chlorinated hydrocarbon catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042205 chlorinated hydrocarbon breakdown|chlorinated hydrocarbon catabolism|chlorinated hydrocarbon degradation The chemical reactions and pathways resulting in the breakdown of chlorinated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with chlorine atoms. GO:0042211 dimethylsilanediol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042211 dimethylsilanediol degradation|dimethylsilanediol breakdown|dimethylsilanediol catabolism|catabolic process of DMSD|degradation of dimethylsilanediol|catabolism of DMSD The aerobic chemical reactions and pathways resulting in the breakdown of dimethylsilanediol, the smallest member of the dialkylsilanediols. Dimethylsilanediol is the monomer of polydimethylsiloxane, a compound which can be found in a wide range of industrial and consumer products. GO:0042210 octamethylcyclotetrasiloxane catabolic process to dimethylsilanediol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042210 UM-BBD_pathwayID:osi octamethylcyclotetrasiloxane degradation to dimethylsilanediol|octamethylcyclotetrasiloxane breakdown to dimethylsilanediol|catabolic process of octamethylcyclotetrasiloxane to DMSD|catabolism of octamethylcyclotetrasiloxane to DMSD The anaerobic chemical reactions and pathways resulting in the breakdown of octamethylcyclotetrasiloxane into dimethylsilanediol. The former is a tetramer of the latter. GO:0042213 m-cresol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042213 MetaCyc:M-CRESOL-DEGRADATION-PWY|UM-BBD_pathwayID:mcr 3-hydroxytoluene catabolism|meta-cresol catabolism|m-cresol degradation|meta-cresol catabolic process|3-hydroxytoluene catabolic process|m-cresol breakdown|m-cresol catabolism The chemical reactions and pathways resulting in the breakdown of m-cresol (3-hydroxytoluene), the meta-isoform of cresol. GO:0042212 cresol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042212 cresol metabolism|hydroxytoluene metabolic process|hydroxytoluene metabolism The chemical reactions and pathways involving cresol, a mixture of the aromatic alcohol isoforms o-, p-, and m-cresol, which is obtained from coal tar or petroleum. The isomers are used as disinfectants, textile scouring agents, surfactants and as intermediates in the manufacture of salicylaldehyde, coumarin, and herbicides as well as being a major component of creosote. GO:0042219 cellular modified amino acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042219 cellular amino acid derivative breakdown|modified amino acid catabolic process|cellular amino acid derivative catabolic process|cellular modified amino acid catabolism|amino acid derivative catabolic process|cellular modified amino acid degradation|cellular modified amino acid breakdown|cellular amino acid derivative catabolism|cellular amino acid derivative degradation|modified amino acid catabolism The chemical reactions and pathways resulting in the breakdown of compounds derived from amino acids, organic acids containing one or more amino substituents. GO:0042218 1-aminocyclopropane-1-carboxylate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042218 1-aminocyclopropane-1-carboxylate biosynthesis|1-aminocyclopropane-1-carboxylate anabolism|1-aminocyclopropane-1-carboxylate synthesis|1-aminocyclopropane-1-carboxylate formation The chemical reactions and pathways resulting in the formation of 1-aminocyclopropane-1-carboxylate, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants. GO:0042215 anaerobic phenol-containing compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042215 UM-BBD_pathwayID:phe anaerobic phenol-containing compound metabolism The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen. GO:0042214 terpene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042214 terpene metabolism The chemical reactions and pathways involving terpenes, any of a large group of hydrocarbons that are made up of isoprene (C5H8) units which may be cyclic, acyclic or multicyclic, saturated or unsaturated, and may contain various functional groups. GO:0042217 1-aminocyclopropane-1-carboxylate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042217 1-aminocyclopropane-1-carboxylate degradation|1-aminocyclopropane-1-carboxylate catabolism|1-aminocyclopropane-1-carboxylate breakdown The chemical reactions and pathways resulting in the breakdown of 1-aminocyclopropane-1-carboxylate, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants. GO:0042216 phenanthrene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042216 UM-BBD_pathwayID:phe phenanthrene breakdown|phenanthrene catabolism|phenanthrene degradation The chemical reactions and pathways resulting in the breakdown of phenanthrene, a tricyclic aromatic hydrocarbon. GO:0042222 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042222 GO:0042221 response to chemical biolink:BiologicalProcess go-plus goslim_yeast|goslim_candida|gocheck_do_not_manually_annotate|goslim_plant|goslim_drosophila|goslim_metagenomics|goslim_aspergillus http://purl.obolibrary.org/obo/GO_0042221 response to chemical stimulus|response to chemical substance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus. GO:0042224 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042224 GO:0042223 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042223 GO:0042220 response to cocaine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042220 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cocaine stimulus. Cocaine is a crystalline alkaloid obtained from the leaves of the coca plant. GO:0042229 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042229 GO:0042226 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042226 GO:0042225 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042225 GO:0042228 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042228 GO:0042227 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042227 GO:0042233 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042233 GO:0042232 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042232 GO:0042235 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042235 GO:0042234 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042234 GO:0042231 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042231 GO:0042230 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042230 GO:0042237 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042237 GO:0042236 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042236 GO:0042239 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042239 GO:0042238 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042238 CHEBI:31459 3,7,12-trioxo-5beta-cholanic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31459 CHEBI:55429 cephamycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55429 CHEBI:31457 decanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_31457 GO:0150156 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0150156 GO:0150155 interleukin-34 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0150155 The appearance of interleukin-34 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0150154 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0150154 GO:0150153 positive regulation of interleukin-17A production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150153 positive regulation of interleukin-17A biosynthetic process Any process that activates or increases the frequency, rate or extent of interleukin-17A production. GO:0150152 negative regulation of interleukin-17A production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150152 negative regulation of interleukin-17A biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-17A production. GO:0150151 regulation of interleukin-17A production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150151 regulation of interleukin-17A biosynthetic process Any process that modulates the frequency, rate or extent of interleukin-17A production. GO:0150150 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0150150 UBERON:0006682 hypoglossal canal biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006682 anterior condylar canal|hyperglossal canal|canalis nervi hypoglossi The hypoglossal canal is a bony canal in the occipital bone of the skull. GO:0150159 negative regulation of interleukin-34 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150159 negative regulation of interleukin-34 biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-34 production. GO:0150158 positive regulation of interleukin-34 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150158 positive regulation of interleukin-34 biosynthetic process Any process that activates or increases the frequency, rate or extent of interleukin-34 production. GO:0150157 regulation of interleukin-34 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150157 regulation of interleukin-34 biosynthetic process|interleukin-34 biosynthetic process Any process that modulates the frequency, rate or extent of interleukin-34 production. UBERON:0006686 spinal vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006686 spinal branch|vena spinalis A vein that is part of a vertebral column. CHEBI:55415 N-acyl-D-homoserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55415 CHEBI:31469 desmethyldescarbamoylnovobiocin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31469 CHEBI:55417 maleimides biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55417 GO:0150167 positive regulation of histone H3-K4 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150167 Any process that activates or increases the frequency, rate or extent of histone H3-K4 acetylation. GO:0150166 regulation of histone H3-K4 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150166 Any process that modulates the frequency, rate or extent of histone H3-K4 acetylation. GO:0150165 miRNA-mediated inhibition of transcription by RNA polymerase II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150165 Any process mediated by a microRNA (miRNA) that stops, prevents or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:0150164 miRNA-mediated regulation of transcription by RNA polymerase II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150164 Any process mediated by a microRNA (miRNA) that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:0150163 miRNA-mediated activation of transcription by RNA polymerase II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150163 Any process mediated by a microRNA (miRNA) that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:0150162 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0150162 GO:0150161 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0150161 GO:0150160 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0150160 UBERON:0006671 orbital fat pad biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006671 orbital fat body|retrobulbar fat|orbital fat|intraorbital fat pad A fat pad that is part of a orbital region. UBERON:0006670 central tendon of diaphragm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006670 centrum tendineum diaphragmatis|centrum tendineum|central tendon the three-lobed cloverleaf-shaped aponeurosis situated at the center of the diaphragm; the central tendon is fused with the fibrous pericardium that provides attachment for the muscle fibers GO:0150169 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0150169 GO:0150168 negative regulation of histone H3-K4 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150168 Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K4 acetylation. CHEBI:31467 descarbamoylnovobiocin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31467 CHEBI:55412 N-acyl-L-homoserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55412 CHEBI:55414 N-acylhomoserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55414 UBERON:0006678 foramen secundum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006678 ostium secundum|foramen secundum A foramen in the septum secundum. CHEBI:31463 delphinidin 3-O-beta-D-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31463 UBERON:0006677 surface of epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006677 epithelium surface An anatomical boundary that adjacent_to a epithelium. CHEBI:55410 anthocyanidin 3-O-(6-O-malonyl-beta-D-glucoside) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55410 UBERON:0006675 venous valve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006675 valve of vein A valve that is part of a vein. CHEBI:55409 6-iminocyclohexa-2,4-dienone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_55409 CHEBI:55404 N-acetyl-D-galactosamine 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55404 CHEBI:55406 beta-D-apiofuranosyl-(1->6)-D-glucopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_55406 GO:0150134 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0150134 GO:0150133 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0150133 GO:0150132 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0150132 GO:0150131 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0150131 GO:0150130 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0150130 GO:0150139 positive regulation of interleukin-37 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150139 positive regulation of interleukin-37 biosynthetic process Any process that activates or increases the frequency, rate or extent of interleukin-37 production. UBERON:0006660 muscular coat biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006660 muscular layer|tunica muscularis|transverse muscular fibers|muscularis propria|tunica muscularis|muscularis externa|muscularis|muscularis layer|muscular coat|tunica externa A region of muscle in many organs in the vertebrate body, adjacent to the submucosa membrane. It is responsible for gut movement such as peristalsis. GO:0150138 negative regulation of interleukin-37 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150138 negative regulation of interleukin-37 biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-37 production. GO:0150137 interleukin-37 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0150137 interleukin-37 biosynthetic process The appearance of interleukin-37 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0150136 regulation of interleukin-37 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150136 regulation of interleukin-37 biosynthetic process Any process that modulates the frequency, rate or extent of interleukin-37 production. GO:0150135 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0150135 CHEBI:55400 3-dehydropyranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55400 CHEBI:31432 corynebactin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_31432 UBERON:0006668 carotid canal biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006668 canalis caroticus On the interior surface of the temporal bone, behind the rough surface of the apex, is the large circular aperture of the carotid canal, which ascends at first vertically, and then, making a bend, runs horizontally forward and medialward. It transmits into the cranium, the internal carotid artery, and the carotid plexus of nerves. Sympathetics to the head also pass through the carotid canal. They have several motor functions: raise the eyelid (superior tarsal muscle), dilate pupil, innervate sweat glands of face and scalp and constricts blood vessels in head[WP]. CHEBI:55402 3-dehydro-D-glucose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_55402 GO:0150145 positive regulation of CD80 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150145 positive regulation of CD80 biosynthetic process Any process that activates or increases the frequency, rate or extent of CD80 biosynthetic process. GO:0150144 negative regulation of CD80 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150144 negative regulation of CD80 biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of CD80 biosynthetic process. GO:0150143 regulation of CD80 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150143 regulation of CD80 biosynthetic process Any process that modulates the frequency, rate or extent of CD80 biosynthetic process. GO:0150142 positive regulation of CD86 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150142 positive regulation of CD86 biosynthetic process Any process that activates or increases the frequency, rate or extent of CD86 biosynthetic process. GO:0150141 negative regulation of CD86 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150141 negative regulation of CD86 biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of CD86 biosynthetic process. GO:0150140 regulation of CD86 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150140 regulation of CD86 biosynthetic process Any process that modulates the frequency, rate or extent of CD86 biosynthetic process. UBERON:0006652 muscular layer of vagina biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006652 vaginal muscularis|tunica muscularis vaginae|muscular coat of vagina GO:0150149 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0150149 GO:0150148 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0150148 GO:0150147 cell-cell junction disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150147 The disaggregation of a cell-cell junction into its constituent components. GO:0150146 cell junction disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150146 The disaggregation of a cell junction into its constituent components. CHEBI:31445 cyclic ADP-ribose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31445 UBERON:0006658 interphalangeal joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006658 inter-phalanx joint|inter-phalangeal joint A joint that connects one phalanx to another along a proximodistal axis. UBERON:0006657 glenoid fossa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006657 glenoid cavity of scapula|cavitas glenoidalis|glenoid cavity|glenoid cavity|cavitas glenoidalis scapulae|glenoid facet|cavitus glenoidalis Anatomical cavity for the proximal articular surface of the proximal limb or fin element with the scapulocoracoid or equivalent structure. UBERON:0006653 glans clitoris biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006653 clitoris glans|glans clitoris|glans clitoridis|glans of clitoris Erectile tissue at the end of the clitoris, which is continuous with the intermediate part of the vestibulovaginal bulbs[BTO]. The clitoral glans (glans clitoridis) is an external portion of the clitoris[WP]. GO:0150112 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0150112 GO:0150111 regulation of transepithelial transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150111 Any process that modulates the frequency, rate or extent of transepithelial transport. GO:0150110 negative regulation of cholesterol esterification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150110 Any process that stops, prevents or reduces the frequency, rate or extent of cholesterol esterification. GO:0150119 negative regulation of protein localization to cell-cell junction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150119 negative regulation of protein localisation to cell-cell junction Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell-cell junction. GO:0150118 negative regulation of cell-substrate junction organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150118 Any process that stops, prevents or reduces the frequency, rate or extent of cell-substrate junction organization. GO:0150117 positive regulation of cell-substrate junction organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150117 Any process that activates or increases the frequency, rate or extent of cell-substrate junction organization. GO:0150116 regulation of cell-substrate junction organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150116 Any process that modulates the frequency, rate or extent of cell-substrate junction organization. GO:0150115 cell-substrate junction organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150115 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-substrate junction. A cell-substrate junction is a specialized region of connection between a cell and the extracellular matrix. GO:0150114 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0150114 GO:0150113 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0150113 GO:0150123 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0150123 GO:0150122 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0150122 GO:0150121 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0150121 GO:0150120 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0150120 GO:0150129 positive regulation of interleukin-33 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150129 positive regulation of interleukin-33 biosynthetic process|positive regulation of interleukin-33 secretion Any process that activates or increases the frequency, rate or extent of interleukin-33 production. GO:0150128 negative regulation of interleukin-33 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150128 negative regulation of interleukin-33 secretion|negative regulation of interleukin-33 biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-33 production. GO:0150127 regulation of interleukin-33 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150127 regulation of interleukin-33 biosynthetic process|regulation of interleukin-33 secretion Any process that modulates the frequency, rate or extent of interleukin-33 production. GO:0150126 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0150126 GO:0150125 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0150125 GO:0150124 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0150124 CHEBI:31402 cinnamyl acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_31402 GO:0150101 regulation of microtubule anchoring at centrosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150101 Any process that modulates the frequency, rate or extent of microtubule anchoring at centrosome. GO:0150100 RNA binding involved in posttranscriptional gene silencing biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0150100 RNA binding involved in quelling|RNA binding involved in post-transcriptional gene silencing|RNA binding involved in cosuppression|RNA binding involved in PTGS Any RNA binding that is involved in posttranscriptional gene silencing. UBERON:0006696 mammillothalamic axonal tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006696 thalamomammillary fasciculus|fasciculus mammillothalamicus|mammillo-thalamic fasciculus|mammillothalamic fasciculus|bundle of vicq d%e2%80%99azyr|mammillothalamic tract|mammillothalamic tract|bundle of vicq d%27azyr|mammillo-thalamic tract|fasciculus mammillothalamicus|vicq d'azyr's bundle|mamillo-thalamic tract A fiber pathway that originates from neurons in the posterior hypothalamic region and projects to various nuclei of the anterior nuclear group of the thalamus. It is a composite structure that consists of the mammillothalamic tract of the hypothalamus and the mammillothalamic tract of the thalamus (Carpenter-1983). (from Brain Info.org) UBERON:0006695 mammillary axonal complex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006695 The mammillary axonal complex is formed by the axons from the lateral, medial mammillary and the dorsal premammillary nuclei which share a branching pattern. Every neuron gives off one axonal stem that bifurcates into 2 branches. One of the branches is directed dorsally to the thalamus and another caudally to the midbrain[GO]. GO:0150107 positive regulation of protein localization to cell-cell junction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150107 Any process that activates or increases the frequency, rate or extent of protein localization to cell-cell junction. UBERON:0006694 cerebellum vasculature biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006694 A vasculature that is part of a cerebellum. GO:0150106 regulation of protein localization to cell-cell junction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150106 Any process that modulates the frequency, rate or extent of protein localization to cell-cell junction. UBERON:0006692 vertebral canal biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006692 neural canal|foramen vertebrale|vertebral canal|spinal cavity|spinal canal|c. vertebralis A conduit enclosed within the vertebral foramen of the vertebrae through which the spinal cord passes. GO:0150105 protein localization to cell-cell junction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150105 A process in which a protein is transported to, or maintained, in a location within a cell-cell junction. GO:0150104 transport across blood-brain barrier biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150104 transport across blood brain barrier|transport across BBB The directed movement of substances (e.g. macromolecules, small molecules, ions) through the blood-brain barrier. GO:0150103 reactive gliosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150103 gliosis A neuroinflammatory response, occurring over several days, during which glial cells undergo nonspecific reactive changes in response to damage to the central nervous system (CNS); typically involves the proliferation or hypertrophy of different types of glial cells. GO:0150102 negative regulation of monocyte activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150102 repression of monocyte activation Any process that stops, prevents or reduces the frequency, rate or extent of monocyte activation. UBERON:0006698 mammillotegmental axonal tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006698 tractus hypothalamotegmentalis|tractus mammillotegmentalis|mammillotegmental tract of hypothalamus|mammillo-tegmental tract|mammillotegmental tract|tractus hypothalamicotegmentalis|medial tegmental tract|mammillotegmental fasciculus|MTG|mammillotegmental tract (Gudden)|fasciculus mamillotegmentalis|Gudden tract|tractus mamillo-tegmentalis|von Gudden's tract The mammillotegmental tract is the collection of axons that connects the ventral diencephalon to the tegmentum and pons UBERON:0006697 mammillotectal axonal tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006697 The mammillotectal tract is the collection of axons that connects the ventral diencephalon to the superior colliculus. GO:0032838 plasma membrane bounded cell projection cytoplasm biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032838 All of the contents of a plasma membrane bounded cell projection, excluding the plasma membrane surrounding the projection. GO:0032837 distributive segregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032837 The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during a normally chiasmate meiosis under the condition that chiasma have not occurred between a particular pair of homologs. Distributive segregation is a backup mechanism to ensure the segregation of homologs that have failed to cross over - either as a consequence of mutation or not, as, for example, the 4th chromosome of Drosophila melanogaster (which never exchanges, presumably due to its small size) - but nevertheless segregate normally. GO:0032836 glomerular basement membrane development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032836 The process whose specific outcome is the progression of the glomerular basement membrane over time, from its formation to the mature structure. The glomerular basement membrane is the basal laminal portion of the glomerulus which performs the actual filtration. GO:0032835 glomerulus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032835 glomerular development The progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney. The glomerulus is part of the nephron and is restricted to one body segment. GO:0032834 positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032834 positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation during immune response|upregulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation during immune response|stimulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|activation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|up-regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation during immune response|positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell development involved in immune response|up regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response Any process that activates or increases the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response. GO:0032833 negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032833 negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell development involved in immune response|negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation during immune response|downregulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|inhibition of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation during immune response|down regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation during immune response|down-regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response Any process that stops, prevents, or reduces the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response. GO:0032832 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032832 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation during immune response|regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation during immune response|regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation during immune response|regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell development involved in immune response|regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response Any process that modulates the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response. GO:0032831 positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032831 up-regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation|positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation|upregulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation|positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation|up regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation|positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell development|activation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation|stimulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation|positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation Any process that activates or increases the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells. GO:0032839 dendrite cytoplasm biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032839 dendritic cytoplasm All of the contents of a dendrite, excluding the surrounding plasma membrane. GO:0032830 negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032830 negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation|inhibition of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation|negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation|down regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation|negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation|downregulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation|negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell development|down-regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells. OBA:0000138 spindle density biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000138 amount of spindle The amount of a spindle. UBERON:0006603 presumptive mesoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006603 Presumptive structure of the blastula that will develop into mesoderm. OBA:0000139 synapse structure and activity biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000139 quality of synapse The quality of a synapse. UBERON:0006601 presumptive ectoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006601 presumptive epidermis Presumptive structure of the blastula that will develop into ectoderm. OBA:0000134 resting membrane potential biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000134 UBERON:0006600 presumptive enteric nervous system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006600 future enteric nervous system CHEBI:137652 N-acetyl-L-alpha-phenylglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137652 OBA:0000136 short-term neuronal synaptic plasticity biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000136 CHEBI:137650 short-chain (3S)-hydroxy fatty acyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137650 GO:0032827 negative regulation of natural killer cell differentiation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032827 negative regulation of natural killer cell differentiation during immune response|down-regulation of natural killer cell differentiation during immune response|negative regulation of NK cell differentiation during immune response|inhibition of natural killer cell differentiation during immune response|downregulation of natural killer cell differentiation during immune response|down regulation of natural killer cell differentiation during immune response|negative regulation of natural killer cell development involved in immune response Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell differentiation as part of an immune response. GO:0032826 regulation of natural killer cell differentiation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032826 regulation of natural killer cell development involved in immune response|regulation of natural killer cell differentiation during immune response|regulation of NK cell differentiation during immune response Any process that modulates the frequency, rate or extent of natural killer cell differentiation as part of an immune response. GO:0032825 positive regulation of natural killer cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032825 upregulation of natural killer cell differentiation|positive regulation of NK cell differentiation|up regulation of natural killer cell differentiation|positive regulation of natural killer cell development|activation of natural killer cell differentiation|stimulation of natural killer cell differentiation|up-regulation of natural killer cell differentiation Any process that activates or increases the frequency, rate or extent of natural killer cell differentiation. OBA:0000121 pH biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000121 GO:0032824 negative regulation of natural killer cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032824 down regulation of natural killer cell differentiation|downregulation of natural killer cell differentiation|negative regulation of NK cell differentiation|negative regulation of natural killer cell development|down-regulation of natural killer cell differentiation|inhibition of natural killer cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell differentiation. GO:0032823 regulation of natural killer cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032823 regulation of NK cell differentiation|regulation of natural killer cell development Any process that modulates the frequency, rate or extent of natural killer cell differentiation. GO:0032822 positive regulation of natural killer cell proliferation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032822 activation of natural killer cell proliferation during immune response|up-regulation of natural killer cell proliferation during immune response|positive regulation of natural killer cell proliferation during immune response|up regulation of natural killer cell proliferation during immune response|positive regulation of NK cell proliferation during immune response|upregulation of natural killer cell proliferation during immune response|stimulation of natural killer cell proliferation during immune response Any process that activates or increases the frequency, rate or extent of natural killer cell proliferation as part of an immune response. GO:0032821 negative regulation of natural killer cell proliferation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032821 negative regulation of natural killer cell proliferation during immune response|down-regulation of natural killer cell proliferation during immune response|negative regulation of NK cell proliferation during immune response|downregulation of natural killer cell proliferation during immune response|inhibition of natural killer cell proliferation during immune response|down regulation of natural killer cell proliferation during immune response Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell proliferation as part of an immune response. GO:0032820 regulation of natural killer cell proliferation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032820 regulation of natural killer cell proliferation during immune response|regulation of NK cell proliferation during immune response Any process that modulates the frequency, rate or extent of natural killer cell proliferation as part of an immune response. GO:0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell development|regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation|regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation|regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation Any process that modulates the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells. GO:0032828 positive regulation of natural killer cell differentiation involved in immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032828 up-regulation of natural killer cell differentiation during immune response|positive regulation of natural killer cell differentiation during immune response|up regulation of natural killer cell differentiation during immune response|positive regulation of NK cell differentiation during immune response|positive regulation of natural killer cell development involved in immune response|upregulation of natural killer cell differentiation during immune response|stimulation of natural killer cell differentiation during immune response|activation of natural killer cell differentiation during immune response Any process that activates or increases the frequency, rate or extent of natural killer cell differentiation as part of an immune response. CHEBI:137668 beta-muricholoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137668 CHEBI:137667 3-[beta-D-glucopyranosyl-(1->6)-beta-D-galactopyranosyl]-1,2-diacyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137667 CHEBI:55491 glycerol 1-phosphodiester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55491 CHEBI:55493 1-O-acylglycerophosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55493 CHEBI:137669 S-[(Z)-N-hydroxy-2-phenylethanimidoyl]-L-cysteinylglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137669 OBA:0000127 pronephric kidney size biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000127 size of pronephros The size of a pronephros. OBA:0000129 rRNA stability biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000129 macromolecular stability of rRNA The macromolecular stability of a rRNA. OBA:0000128 protein stability biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000128 macromolecular stability of protein The macromolecular stability of a protein. CHEBI:137664 allodeoxycholoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137664 OBA:0000123 plasma membrane sterol distribution biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000123 plasma membrane sterol spatial pattern The spatial pattern of a sterol when measured in plasma membrane. OBA:0000122 peroxisome size biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000122 size of peroxisome The size of a peroxisome. CHEBI:137663 allocholoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137663 CHEBI:137662 allodeoxycholate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137662 CHEBI:137661 allocholate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137661 OBA:0000124 post-lysosomal vacuole size biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000124 size of post-lysosomal vacuole The size of a post-lysosomal vacuole. GO:0032816 positive regulation of natural killer cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032816 positive regulation of NK cell activation|upregulation of natural killer cell activation|stimulation of natural killer cell activation|up-regulation of natural killer cell activation|activation of natural killer cell activation|up regulation of natural killer cell activation Any process that activates or increases the frequency, rate or extent of natural killer cell activation. GO:0032815 negative regulation of natural killer cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032815 downregulation of natural killer cell activation|down regulation of natural killer cell activation|inhibition of natural killer cell activation|down-regulation of natural killer cell activation|negative regulation of NK cell activation Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation. GO:0032814 regulation of natural killer cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032814 regulation of NK cell activation Any process that modulates the frequency, rate or extent of natural killer cell activation. OBA:0000110 muscle filament sliding speed biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000110 speed of muscle filament sliding The speed of a muscle filament sliding. GO:0032813 tumor necrosis factor receptor superfamily binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032813 TNF receptor superfamily binding Interacting selectively and non-covalently with any member of the tumor necrosis factor receptor superfamily. GO:0032812 positive regulation of epinephrine secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032812 upregulation of epinephrine secretion|up regulation of epinephrine secretion|activation of epinephrine secretion|stimulation of epinephrine secretion|positive regulation of adrenaline secretion|up-regulation of epinephrine secretion Any process that activates or increases the frequency, rate or extent of the regulated release of epinephrine. GO:0032811 negative regulation of epinephrine secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032811 down regulation of epinephrine secretion|downregulation of epinephrine secretion|down-regulation of epinephrine secretion|negative regulation of adrenaline secretion|inhibition of epinephrine secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of epinephrine. GO:0032810 sterol response element binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032810 SRE binding Interacting selectively and non-covalently with the sterol response element (SRE), a nonpalindromic sequence found in the promoters of genes involved in lipid metabolism. GO:0032819 positive regulation of natural killer cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032819 up-regulation of natural killer cell proliferation|upregulation of natural killer cell proliferation|positive regulation of NK cell proliferation|up regulation of natural killer cell proliferation|activation of natural killer cell proliferation|stimulation of natural killer cell proliferation Any process that activates or increases the frequency, rate or extent of natural killer cell proliferation. GO:0032818 negative regulation of natural killer cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032818 down-regulation of natural killer cell proliferation|inhibition of natural killer cell proliferation|down regulation of natural killer cell proliferation|downregulation of natural killer cell proliferation|negative regulation of NK cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell proliferation. GO:0032817 regulation of natural killer cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032817 regulation of NK cell proliferation Any process that modulates the frequency, rate or extent of natural killer cell proliferation. CHEBI:137639 long-chain (3S)-hydroxy fatty acyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137639 OBA:0000119 nucleosome density biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000119 amount of nucleosome The amount of a nucleosome. OBA:0000116 neurotransmitter levels biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000116 amount of neurotransmitter The amount of a neurotransmitter. OBA:0000117 nuclear size biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000117 size of nucleus The size of a nucleus. OBA:0000112 myofibril number biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000112 amount of myofibril The amount of a myofibril. CHEBI:55485 dermatan 6'-sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55485 CHEBI:55484 alpha-phenylglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55484 OBA:0000114 neuronal synaptic plasticity biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000114 synaptic plasticity of neuron The synaptic plasticity of a neuron. OBA:0000113 myofibril size biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000113 size of myofibril The size of a myofibril. GO:0032805 positive regulation of low-density lipoprotein particle receptor catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032805 positive regulation of low-density lipoprotein receptor catabolic process|up regulation of low-density lipoprotein receptor catabolic process|upregulation of low-density lipoprotein receptor catabolic process|positive regulation of low-density lipoprotein receptor catabolism|stimulation of low-density lipoprotein receptor catabolic process|up-regulation of low-density lipoprotein receptor catabolic process|activation of low-density lipoprotein receptor catabolic process|positive regulation of low-density lipoprotein receptor degradation|positive regulation of low-density lipoprotein receptor breakdown Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein particle receptors. GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032804 downregulation of low-density lipoprotein receptor catabolic process|negative regulation of low-density lipoprotein receptor catabolic process|down regulation of low-density lipoprotein receptor catabolic process|inhibition of low-density lipoprotein receptor catabolic process|negative regulation of low-density lipoprotein receptor catabolism|negative regulation of low-density lipoprotein receptor degradation|negative regulation of low-density lipoprotein receptor breakdown|down-regulation of low-density lipoprotein receptor catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein receptors. GO:0032803 regulation of low-density lipoprotein particle receptor catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032803 regulation of LDLr catabolism|regulation of low-density lipoprotein receptor breakdown|regulation of low-density lipoprotein receptor catabolic process|regulation of low-density lipoprotein receptor catabolism|regulation of LDLr catabolic process|regulation of low-density lipoprotein receptor degradation Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein particle receptors. GO:0032802 low-density lipoprotein particle receptor catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032802 low-density lipoprotein receptor catabolic process|LDL receptor degradation|low-density lipoprotein receptor degradation|low-density lipoprotein receptor catabolism|LDL receptor breakdown|low-density lipoprotein receptor breakdown|LDL receptor catabolic process|LDL receptor catabolism The chemical reactions and pathways resulting in the breakdown of a low-density lipoprotein particle receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. GO:0032801 receptor catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032801 receptor breakdown|receptor catabolism|receptor degradation The chemical reactions and pathways resulting in the breakdown of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. GO:0032800 obsolete receptor biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032800 receptor anabolism|receptor biosynthesis|receptor synthesis|receptor formation OBSOLETE. The chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. GO:0032809 neuronal cell body membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032809 neuron cell body membrane|neuronal cell soma membrane The plasma membrane of a neuron cell body - excludes the plasma membrane of cell projections such as axons and dendrites. GO:0032808 lacrimal gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032808 The process whose specific outcome is the progression of the lacrimal gland over time, from its formation to the mature structure. The lacrimal gland produces secretions that lubricate and protect the cornea of the eye. GO:0032807 DNA ligase IV complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032807 DNA ligase IV-XRCC4 complex A eukaryotically conserved protein complex that contains DNA ligase IV and is involved in DNA repair by non-homologous end joining; in addition to the ligase, the complex also contains XRCC4 or a homolog, e.g. Saccharomyces Lif1p. GO:0032806 carboxy-terminal domain protein kinase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032806 CTDK complex A protein complex that phosphorylates amino acid residues of RNA polymerase II C-terminal domain repeats; phosphorylation occurs mainly on Ser2 and Ser5. CHEBI:137643 (22E)-3-oxochola-4,22-dien-24-oyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137643 OBA:0000105 mitochondrial membrane potential biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000105 membrane potential of mitochondrial membrane The membrane potential of a mitochondrial membrane. CHEBI:55478 beta-GlcNAc-(1->4)-MurNAc-L-Ala-gamma-D-Glu-N(6)-(beta-D-Asp)-L-Lys-(D-Ala)2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55478 OBA:0000104 mitochondrial membrane permeability biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000104 permeability of mitochondrial membrane The permeability of a mitochondrial membrane. OBA:0000107 multivesicular body size biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000107 size of multivesicular body The size of a multivesicular body. OBA:0000106 mitochondrial rRNA stability biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000106 mitochondrion rRNA macromolecular stability The macromolecular stability of a rRNA when measured in mitochondrion. CHEBI:55479 cis-3-hydroxy-L-proline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55479 OBA:0000101 metanephric kidney size biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000101 size of metanephros The size of a metanephros. CHEBI:55474 N-acyl-L-homoserine lactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_55474 OBA:0000103 mitochondrial mRNA stability biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000103 mitochondrion mRNA macromolecular stability The macromolecular stability of a mRNA when measured in mitochondrion. CHEBI:55476 N-formyl-D-kynurenine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55476 OBA:0000102 microvillus length biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000102 length of microvillus The length of a microvillus. GO:0150192 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0150192 OBA:0000174 vascular permeability biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000174 permeability of vessel The permeability of a vessel. GO:0150191 positive regulation of interleukin-32 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150191 positive regulation of interleukin-32 biosynthetic process|positive regulation of interleukin-32 secretion Any process that activates or increases the frequency, rate or extent of interleukin-32 production. OBA:0000173 urinary volume biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000173 volume of urine The volume of a urine. GO:0150190 negative regulation of interleukin-32 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150190 negative regulation of interleukin-32 secretion|negative regulation of interleukin-32 biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-32 production. OBA:0000172 tube size biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000172 size of tube The size of a tube. OBA:0000171 tube diameter biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000171 diameter of tube The diameter of a tube. GO:0150195 transport across blood-cerebrospinal fluid barrier biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150195 transport across BCSFB|transport across blood/cerebrospinal fluid barrier|transport across blood-CSF barrier|transport across blood/CSF barrier The directed movement of substances (e.g. macromolecules, small molecules, ions) through the blood-cerebrospinal fluid barrier. GO:0150194 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0150194 GO:0150193 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0150193 CHEBI:55467 dalpatein beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_55467 UBERON:0006648 adventitia of seminal vesicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006648 adventitia of seminal gland|seminal vesicle adventitia|tunica adventitia glandulae vesiculosae|tunica adventitia (vesicula seminalis) An adventitia that is part of a seminal vesicle. UBERON:0006647 adventitia of ductus deferens biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006647 tunica adventitia (ductus deferens)|adventitia of vas deferens|adventitia of ductus deferens|deferent ductal adventitia|adventitia of deferent duct|tunica adventitia ductus deferentis An adventitia that is part of a vas deferens. CHEBI:55469 N-acetyl-2-arylethylamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_55469 UBERON:0006646 muscle layer of epididymis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006646 A muscle layer that is part of a epididymis. UBERON:0006645 adventitia of epididymis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006645 epididymis adventitia An adventitia that is part of a epididymis. CHEBI:55465 7-hydroxyisoflavones biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_55465 UBERON:0006642 muscle layer of oviduct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006642 muscular coat of uterine tube|muscle layer of fallopian tube|uterine tubal muscularis|muscular layer of uterine tube|muscularis of uterine tube|tunica muscularis (Tuba uterina)|tunica muscularis tubae uterinae|muscle layer of uterine tube|muscle layer of oviduct A muscle layer that is part of a fallopian tube. CHEBI:55464 7-[beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranosyloxy]isoflavone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55464 OBA:0000164 velocity of shortening of skeletal muscle modulating contraction biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000164 the velocity of shortening of skeletal muscle modulating contraction|velocity of shortening of skeletal muscle|speed of skeletal muscle contraction The speed of a skeletal muscle contraction. OBA:0000161 force of heart contraction biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000161 the force of heart contraction|force of heart contraction The force of a heart contraction. OBA:0000160 thalamus size biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000160 size of dorsal plus ventral thalamus The size of a dorsal plus ventral thalamus. CHEBI:137626 EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137626 CHEBI:55456 delphinidin 3,3',5-tri-O-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55456 CHEBI:55455 delphinidin 3-O-beta-D-glucoside-5-O-beta-D-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55455 CHEBI:55458 1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_55458 OBA:0000167 tracheal tube length biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000167 length of respiratory tube The length of a respiratory tube. CHEBI:3230 butachlor biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_3230 OBA:0000166 tracheal tube diameter biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000166 diameter of respiratory tube The diameter of a respiratory tube. CHEBI:55451 lipoyl-AMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55451 OBA:0000169 translational accuracy biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000169 functionality of translation|translational fidelity The functionality of a translation. UBERON:0006632 musculo-phrenic artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006632 musculophrenic artery An artery with its origin in the lateral terminal branch of the internal thoracic artery, with distribution to the diaphragm and the intercostal muscles, and with anastomoses to the branches of the pericardiacophrenic and inferior phrenic. OBA:0000168 tracheal tube size biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000168 size of respiratory tube The size of a respiratory tube. GO:0150170 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0150170 UBERON:0006617 left external ear biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006617 left auricular region An external ear that is in the left side of a multicellular organism. GO:0150178 regulation of phosphatidylserine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150178 Any process that modulates the frequency, rate or extent of phosphatidylserine metabolic process. GO:0150177 negative regulation of phosphatidylethanolamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150177 Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylethanolamine metabolic process. GO:0150176 positive regulation of phosphatidylethanolamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150176 Any process that activates or increases the frequency, rate or extent of phosphatidylethanolamine metabolic process. GO:0150175 regulation of phosphatidylethanolamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150175 Any process that modulates the frequency, rate or extent of phosphatidylethanolamine metabolic process. GO:0150174 negative regulation of phosphatidylcholine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150174 Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylcholine metabolic process. GO:0150173 positive regulation of phosphatidylcholine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150173 Any process that activates or increases the frequency, rate or extent of phosphatidylcholine metabolic process. GO:0150172 regulation of phosphatidylcholine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150172 Any process that modulates the frequency, rate or extent of phosphatidylcholine metabolic process. GO:0150171 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0150171 GO:0150179 positive regulation of phosphatidylserine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150179 Any process that activates or increases the frequency, rate or extent of phosphatidylserine metabolic process. OBA:0000141 synaptic plasticity biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000141 GO:0150180 negative regulation of phosphatidylserine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150180 Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylserine metabolic process. OBA:0000140 synaptic metaplasticity biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000140 OBA:0000143 systemic arterial blood pressure biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000143 systemic artery blood pressure The pressure of a blood when measured in systemic artery. CHEBI:55438 Ile(5)-angiotensin II (1-7) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55438 CHEBI:55437 2-demethylmenaquinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_55437 UBERON:0006606 mandibular symphysis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006606 inter-dentary joint|symphysis mandibulae|symphysis menti|mental symphysis|inter-mandibular joint|dentary symphysis A cartilaginous joint that connects left and right mandibles/dentary bones. Mandibular symphysis is unpaired[TAO,modified]. GO:0150189 regulation of interleukin-32 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150189 regulation of interleukin-32 secretion|regulation of interleukin-32 biosynthetic process Any process that modulates the frequency, rate or extent of interleukin-32 production. GO:0150188 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0150188 CHEBI:137600 2-hydroxy-7,8-dihydropteroate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137600 UBERON:0006616 right external ear biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006616 right auricular region An external ear that is in the right side of a multicellular organism. CHEBI:31488 N-acylsphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_31488 CHEBI:55436 2-arylethylamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55436 CHEBI:55435 beta-Asp-Arg biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55435 CHEBI:55430 1-O-hexadecyl-2-arachidonoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_55430 CHEBI:3211 bulbocapnine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_3211 GO:0042365 water-soluble vitamin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042365 water-soluble vitamin catabolism|water-soluble vitamin degradation|water-soluble vitamin breakdown The chemical reactions and pathways resulting in the breakdown of any of a diverse group of vitamins that are soluble in water. GO:0042364 water-soluble vitamin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042364 water-soluble vitamin anabolism|water-soluble vitamin synthesis|water-soluble vitamin formation|water-soluble vitamin biosynthesis The chemical reactions and pathways resulting in the formation of any of a diverse group of vitamins that are soluble in water. GO:0042367 biotin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042367 vitamin B7 catabolism|vitamin B7 catabolic process|biotin catabolism|vitamin H catabolic process|biotin degradation|vitamin H catabolism|biotin breakdown The chemical reactions and pathways resulting in the breakdown of biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid. GO:0042366 cobalamin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042366 cobalamin catabolism|vitamin B12 catabolism|cobalamin degradation|cobalamin breakdown|vitamin B12 catabolic process The chemical reactions and pathways resulting in the breakdown of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom. GO:0042361 menaquinone catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042361 menatetrenone catabolic process|menaquinone catabolism|vitamin K2 catabolism|menaquinone degradation|multiprenylmenaquinone catabolic process|multiprenylmenaquinone catabolism|menaquinone breakdown|vitamin K2 catabolic process|menatetrenone catabolism The chemical reactions and pathways resulting in the breakdown of menaquinones, any of the quinone-derived compounds synthesized by intestinal bacteria. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones have vitamin K activity and are known as vitamin K2. GO:0042360 vitamin E metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042360 tocopherol metabolism|alpha-tocopherol metabolic process|alpha-tocopherol metabolism|vitamin E metabolism|tocopherol metabolic process The chemical reactions and pathways involving vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant. GO:0042363 fat-soluble vitamin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042363 fat-soluble vitamin catabolism|fat-soluble vitamin degradation|fat-soluble vitamin breakdown The chemical reactions and pathways resulting in the breakdown of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water. GO:0042362 fat-soluble vitamin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042362 fat-soluble vitamin synthesis|fat-soluble vitamin formation|fat-soluble vitamin biosynthesis|fat-soluble vitamin anabolism The chemical reactions and pathways resulting in the formation of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water. GO:0042369 vitamin D catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042369 ergocalciferol biosynthetic process|ergocalciferol biosynthesis|calciferol catabolic process|vitamin D degradation|vitamin D catabolism|calciferol catabolism|vitamin D breakdown|cholecalciferol biosynthetic process|cholecalciferol biosynthesis The chemical reactions and pathways resulting in the breakdown of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3). GO:0042368 vitamin D biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042368 vitamin D anabolism|vitamin D synthesis|vitamin D formation|ergocalciferol biosynthetic process|ergocalciferol biosynthesis|vitamin D biosynthesis|calciferol biosynthesis|calciferol biosynthetic process|cholecalciferol biosynthesis|cholecalciferol biosynthetic process The chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3). GO:0042370 thiamine diphosphate dephosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042370 thiamin diphosphate dephosphorylation|TPP dephosphorylation The removal of one or more phosphate groups from thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle. GO:0042376 phylloquinone catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042376 vitamin K1 catabolism|phytomenadione catabolic process|phytomenadione catabolism|phylloquinone degradation|vitamin K1 catabolic process|phylloquinone breakdown|phytonadione catabolic process|phytylmenaquinone catabolic process|phytylmenaquinone catabolism|phylloquinone catabolism|phytonadione catabolism The chemical reactions and pathways resulting in the breakdown of phylloquinone, vitamin K1, a quinone-derived compound synthesized by green plants. GO:0042375 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042375 GO:0042378 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042378 GO:0042377 vitamin K catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042377 vitamin K catabolism|naphthoquinone catabolic process|vitamin K degradation|naphthoquinone catabolism|vitamin K breakdown The chemical reactions and pathways resulting in the breakdown of any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals. GO:0042372 phylloquinone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042372 MetaCyc:PWY-5027 vitamin K1 biosynthetic process|vitamin K1 biosynthesis|phytomenadione biosynthesis|phytomenadione biosynthetic process|phylloquinone anabolism|phylloquinone synthesis|phytylmenaquinone biosynthesis|phytylmenaquinone biosynthetic process|phylloquinone formation|phylloquinone biosynthesis|phytonadione biosynthesis|phytonadione biosynthetic process The chemical reactions and pathways resulting in the formation of phylloquinone, vitamin K1, a quinone-derived compound synthesized by green plants. GO:0042371 vitamin K biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042371 vitamin K anabolism|vitamin K synthesis|naphthoquinone metabolism|vitamin K biosynthesis|vitamin K formation|naphthoquinone metabolic process The chemical reactions and pathways resulting in the formation of any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals. GO:0042374 phylloquinone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042374 phylloquinone metabolism|vitamin K1 metabolic process|phytonadione metabolism|vitamin K1 metabolism|phytonadione metabolic process|phytomenadione metabolism|phytylmenaquinone metabolic process|phytomenadione metabolic process|phytylmenaquinone metabolism The chemical reactions and pathways involving phylloquinone, a quinone-derived compound synthesized by green plants. Phylloquinone has vitamin K activity and is known as vitamin K1. GO:0042373 vitamin K metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042373 naphthoquinone metabolism|vitamin K metabolism|naphthoquinone metabolic process The chemical reactions and pathways involving any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals. Vitamin K substances share a methylated naphthoquinone ring structure and vary in the aliphatic side chains attached to the molecule. GO:0042379 chemokine receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042379 chemokine receptor ligand Interacting selectively and non-covalently with any chemokine receptor. GO:0042381 hemolymph coagulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042381 hemolymph clotting Any process in which factors in the hemolymph (the invertebrate equivalent of vertebrate blood and lymph) precipitate into insoluble clots in order to prevent loss of body fluid, and at the same time prevent the movement of microbes. Hemolymph coagulation is also part of the invertebrate humoral immune response. GO:0042380 hydroxymethylbutenyl pyrophosphate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042380 (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase (IPP and DMAPP forming) Catalysis of the formation of both isopentenyl pyrophosphate and dimethylallyl pyrophosphate from (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate. GO:0042387 plasmatocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042387 The process in which a hemocyte precursor cell acquires the characteristics of the phagocytic blood-cell type, the plasmatocyte. Plasmatocytes are a class of arthropod hemocytes important in the cellular defense response. GO:0042386 hemocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042386 arthropod blood cell differentiation The process in which a relatively unspecialized cell acquires the characteristics of a mature hemocyte. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. GO:0042389 omega-3 fatty acid desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042389 EC:1.14.99.- Catalysis of the introduction of an omega-3 double bond into the fatty acid hydrocarbon chain. GO:0042388 gibberellic acid mediated signaling pathway, G-alpha-dependent biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042388 gibberellic acid mediated signalling, G-alpha-dependent A series of molecular signals mediated by the detection of gibberellic acid and dependent on the coupling of the alpha subunit of G proteins to the hormone receptors. GO:0042383 sarcolemma biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042383 Wikipedia:Sarcolemma The outer membrane of a muscle cell, consisting of the plasma membrane, a covering basement membrane (about 100 nm thick and sometimes common to more than one fiber), and the associated loose network of collagen fibers. GO:0042382 paraspeckles biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042382 Wikipedia:Paraspeckle Discrete subnuclear bodies in the interchromatin nucleoplasmic space, often located adjacent to nuclear specks. 10-20 paraspeckles are typically found in human cell nuclei. GO:0042385 myosin III complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042385 A myosin complex containing a class III myosin heavy chain and associated light chains; myosin III is monomeric myosin that serves as a link between the cytoskeleton and the signaling complex involved in phototransduction, and differs from all other myosins in having an N-terminal kinase domain. GO:0042384 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042384 GO:0042390 gibberellic acid mediated signaling pathway, G-alpha-independent biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042390 gibberellic acid mediated signalling, G-alpha-independent A series of molecular signals mediated by the detection of gibberellic acid and not dependent on the coupling of the alpha subunit of G proteins to the hormone receptors. GO:0042392 sphingosine-1-phosphate phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042392 RHEA:27518|MetaCyc:RXN3DJ-25|Reactome:R-HSA-428701|Reactome:R-HSA-428696|Reactome:R-HSA-428690 SPP phosphatase activity|SPPase activity|sphingosine-1-phosphate phosphohydrolase activity Catalysis of the reaction: sphingosine 1-phosphate + H2O = sphingosine + phosphate. GO:0042391 regulation of membrane potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042391 Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. OBA:0000181 viral protein levels biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000181 OBA:0000183 blood vessel diameter biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000183 diameter of blood vessel The diameter of a blood vessel. GO:0042398 cellular modified amino acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042398 cellular modified amino acid anabolism|cellular modified amino acid synthesis|cellular modified amino acid formation|cellular amino acid derivative anabolism|cellular modified amino acid biosynthesis|cellular amino acid derivative synthesis|amino acid derivative biosynthetic process|cellular amino acid derivative formation|cellular amino acid derivative biosynthetic process|cellular amino acid derivative biosynthesis The chemical reactions and pathways resulting in the formation of compounds derived from amino acids, organic acids containing one or more amino substituents. GO:0042397 phosphagen catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042397 phosphagen catabolism|phosphagen degradation|phosphagen breakdown The chemical reactions and pathways resulting in the breakdown of phosphagen, any of a group of guanidine phosphates that occur in muscle and can be used to regenerate ATP from ADP during muscular contraction. GO:0042399 ectoine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042399 ectoine metabolism The chemical reactions and pathways involving ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid), a tetrahydropyrimidine commonly synthesized by halophilic bacteria. GO:0042394 obsolete ecdysis, protein-based cuticle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042394 ecdysis, protein-based cuticle OBSOLETE. The shedding of the old protein-based cuticular fragments during the molting cycle. Examples of this process are found in invertebrates. GO:0042393 histone binding biolink:MolecularActivity go-plus goslim_chembl|goslim_yeast|goslim_drosophila|goslim_generic http://purl.obolibrary.org/obo/GO_0042393 histone-specific chaperone activity Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity. GO:0042396 phosphagen biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042396 phosphagen synthesis|phosphagen formation|phosphagen biosynthesis|phosphagen anabolism The chemical reactions and pathways resulting in the formation of phosphagen, any of a group of guanidine phosphates that occur in muscle and can be used to regenerate ATP from ADP during muscular contraction. GO:0042395 ecdysis, collagen and cuticulin-based cuticle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042395 The shedding of the old collagen and cuticulin-based cuticle fragments during the molting cycle. Examples of this process are found in invertebrates. CHEBI:3015 benomyl biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_3015 GO:0032999 Fc-alpha receptor I complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032999 FcaRI complex|immunoglobulin A receptor complex|IgA receptor complex A protein complex composed of an Fc-alpha R alpha chain and an Fc-epsilon RI gamma chain dimer with or without additional signaling components. The complex functions primarily as an activating receptor for IgA. GO:0032998 Fc-epsilon receptor I complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032998 FceRI complex|immunoglobulin E receptor complex|IgE receptor complex A protein complex composed of an Fc-epsilon RI alpha chain and an Fc-epsilon RI gamma chain dimer with or without an Fc-episilon RI beta chain and additional signaling components. The complex functions primarily as an activating receptor for IgE. GO:0032997 Fc receptor complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0032997 FcR complex|immunoglobulin receptor complex|Fc-receptor complex A protein complex composed of a subunit or subunits capable of binding the Fc portion of an immunoglobulin with additional signaling components. The complex functions as a receptor for immunoglobulin. GO:0032996 Bcl3-Bcl10 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032996 A protein complex containing Bcl3 and Bcl10, which forms when Akt1 is activated by TNF-alpha to phosphorylate Bcl10; the Bcl3-Bcl10 complex is translocated to the nucleus. CHEBI:137699 15,17(3)-seco-F430-17(3)-acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137699 GO:0032995 regulation of fungal-type cell wall biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032995 regulation of chitin- and beta-glucan-containing cell wall biogenesis Any process that modulates the process in which a cell wall is synthesized, aggregates, and bonds together. The fungal-type cell wall contains beta-glucan and may contain chitin. GO:0032994 protein-lipid complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032994 A macromolecular complex containing separate protein and lipid molecules. Separate in this context means not covalently bound to each other. GO:0032993 protein-DNA complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0032993 DNA-protein complex A macromolecular complex containing both protein and DNA molecules. GO:0032992 protein-carbohydrate complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032992 A macromolecular complex containing separate protein and carbohydrate molecules. Separate in this context means not covalently bound to each other. GO:0032991 protein-containing complex biolink:CellularComponent go-plus goslim_agr|goslim_pir|goslim_generic|goslim_flybase_ribbon|goslim_chembl http://purl.obolibrary.org/obo/GO_0032991 protein-protein complex|macromolecule complex|protein containing complex|protein complex|macromolecular complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. GO:0032990 cell part morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032990 The process in which the anatomical structures of a cell part are generated and organized. CHEBI:137696 nickel-sirohydrochlorin a,c-diamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137696 GO:0032989 cellular component morphogenesis biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0032989 cellular structure morphogenesis The process in which cellular structures, including whole cells or cell parts, are generated and organized. GO:0032988 ribonucleoprotein complex disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032988 protein-RNA complex disassembly|RNA-protein complex disassembly|RNP complex disassembly The disaggregation of a protein-RNA complex into its constituent components. GO:0032987 protein-lipid complex disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032987 The disaggregation of a protein-lipid complex into its constituent components. GO:0032986 protein-DNA complex disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032986 DNA-protein complex disassembly The disaggregation of a protein-DNA complex into its constituent components. GO:0032985 protein-carbohydrate complex disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032985 The disaggregation of a protein-carbohydrate complex into its constituent components. GO:0032984 protein-containing complex disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032984 cellular macromolecule complex disassembly|macromolecule complex disassembly|protein complex disassembly The disaggregation of a protein-containing macromolecular complex into its constituent components. GO:0032983 kainate selective glutamate receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032983 An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. Kainate receptors are multimeric assemblies of GluK1-3 (also called GluR5-7), GluK4 (KA1) and GluK5 (KA2) subunits. GO:0032982 myosin filament biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032982 myosin thick filament|thick filament A supramolecular fiber containing myosin heavy chains, plus associated light chains and other proteins, in which the myosin heavy chains are arranged into a filament. GO:0032981 mitochondrial respiratory chain complex I assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032981 mitochondrial complex I assembly|mitochondrial NADH dehydrogenase complex (ubiquinone) assembly The aggregation, arrangement and bonding together of a set of components to form mitochondrial respiratory chain complex I. GO:0032980 keratinocyte activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032980 A change in the morphology or behavior of a keratinocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. Upon activation, keratinocytes become migratory and hyperproliferative, and produce growth factors and cytokines. GO:0032979 protein insertion into mitochondrial inner membrane from matrix biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032979 protein insertion into mitochondrial membrane from inner side|insertion of proteins into the mitochondrial membrane from the inner side|protein insertion into mitochondrial inner membrane from matrix side The process in which a protein is incorporated into the mitochondrial inner membrane from the matrix side. This includes membrane insertion of newly synthesized mitochondrially-encoded proteins, and insertion of nuclear-encoded proteins after their import into the mitochondrial matrix. GO:0032978 protein insertion into membrane from inner side biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032978 insertion of proteins into membrane from the inner side The process in which a protein is incorporated into a lipid bilayer, e.g., the prokaryotic, mitochondrial, or chloroplast inner membrane, from the inner side. GO:0032977 membrane insertase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032977 Reactome:R-HSA-1299482|Reactome:R-HSA-1268025|Reactome:R-HSA-1307803 Binds transmembrane domain-containing proteins and mediates their integration into a membrane. GO:0032976 release of matrix enzymes from mitochondria biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032976 release of aspartate aminotransferase from mitochondria|mAST release from mitochondria The process in which enzymes, such as aspartate aminotransferase, are enabled to move from the mitochondrial matrix into the cytosol, as part of the apoptotic process. GO:0032975 amino acid transmembrane import into vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032975 vacuolar amino acid import The directed movement of amino acids into the vacuole across the vacuolar membrane. GO:0032974 amino acid transmembrane export from vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032974 amino acid efflux from vacuole|vacuolar amino acid export The directed movement of amino acids out of the vacuole, across the vacuolar membrane. CHEBI:137679 ursodeoxycholoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137679 CHEBI:137678 nickel-sirohydrochlorin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137678 CHEBI:137677 glycolaldehyde triphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137677 CHEBI:137676 Cys(IAN)-Gly biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137676 GO:0032973 amino acid export across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032973 amino acid transmembrane export|amino acid efflux|amino acid export The directed movement of amino acids from inside of a cell, across the plasma membrane and into the extracellular region. GO:0032972 regulation of muscle filament sliding speed biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032972 Any process that modulates the velocity of muscle filament sliding. GO:0032971 regulation of muscle filament sliding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032971 Any process that modulates the frequency, rate or extent of muscle filament sliding. GO:0032970 regulation of actin filament-based process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032970 Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton. CHEBI:137675 thiobenzaldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137675 CHEBI:137674 benzyl thiol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137674 CHEBI:137673 3-sulfinatopropionate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137673 CHEBI:137672 S-[(E)-N-hydroxy-2-(indol-3-yl)ethanimidoyl]-L-cysteinylglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137672 GO:0032969 endosomal scaffold complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032969 MP1-p14 scaffolding complex|endosomal adaptor complex A protein complex that contains MAPKSP1 (MP1, Map2k1ip1) and ROBLD3 (p14, Mapbpip), is anchored to late endosomes, and is involved in selective activation of the ERK1 in ERK/MAPK signaling. GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032968 positive regulation of gene-specific transcription elongation from RNA polymerase II promoter|positive regulation of RNA elongation from RNA polymerase II promoter Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II. GO:0032967 positive regulation of collagen biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032967 positive regulation of collagen synthesis|positive regulation of collagen formation|positive regulation of collagen biosynthesis|positive regulation of collagen anabolism Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. GO:0032966 negative regulation of collagen biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032966 negative regulation of collagen biosynthesis|negative regulation of collagen anabolism|negative regulation of collagen synthesis|negative regulation of collagen formation Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. GO:0032965 regulation of collagen biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032965 regulation of collagen anabolism|regulation of collagen synthesis|regulation of collagen formation|regulation of collagen biosynthesis Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. GO:0032964 collagen biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032964 collagen anabolism|collagen biosynthesis|collagen synthesis|collagen formation The chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%). GO:0032963 collagen metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032963 collagen metabolism The chemical reactions and pathways involving collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%). CHEBI:55393 (S)-piperazine-2-carboxylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55393 CHEBI:55392 (S)-piperazine-2-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55392 CHEBI:137688 (25R)-26-hydroxycholestanol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137688 CHEBI:137687 (24S)-hydroxycholestanol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137687 CHEBI:55391 (S)-piperazine-2-carboxamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55391 CHEBI:55390 dicarbide(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55390 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032962 positive regulation of myo-inositol trisphosphate biosynthetic process|positive regulation of myo-inositol trisphosphate biosynthesis|positive regulation of IP3 biosynthesis|positive regulation of IP3 biosynthetic process|positive regulation of inositol trisphosphate anabolism|positive regulation of inositol trisphosphate synthesis|positive regulation of inositol trisphosphate formation|positive regulation of inositol trisphosphate biosynthesis Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate. GO:0032961 negative regulation of inositol trisphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032961 negative regulation of myo-inositol trisphosphate biosynthesis|negative regulation of myo-inositol trisphosphate biosynthetic process|negative regulation of IP3 biosynthesis|negative regulation of IP3 biosynthetic process|negative regulation of inositol trisphosphate anabolism|negative regulation of inositol trisphosphate synthesis|negative regulation of inositol trisphosphate formation|negative regulation of inositol trisphosphate biosynthesis Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate. GO:0032960 regulation of inositol trisphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032960 regulation of IP3 biosynthetic process|regulation of IP3 biosynthesis|regulation of inositol trisphosphate anabolism|regulation of inositol trisphosphate biosynthesis|regulation of myo-inositol trisphosphate biosynthesis|regulation of inositol trisphosphate synthesis|regulation of myo-inositol trisphosphate biosynthetic process|regulation of inositol trisphosphate formation Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate. CHEBI:55396 2-dehydropyranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55396 CHEBI:55399 L-aminoacyl-L-amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55399 CHEBI:137684 Papio hamadryas metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137684 GO:0101020 estrogen 16-alpha-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0101020 oestrogen 16-alpha-hydroxylase activity Catalysis of the reaction: estrogen + donor-H2 + O2 = 16-alpha-hydroxyestrogen + H2O. GO:0101021 estrogen 2-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0101021 oestrogen 2-hydroxylase activity Catalysis of the reaction: estrogen + donor-H2 + O2 = 2-hydroxyestrogen + H2O. GO:0101024 mitotic nuclear membrane organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0101024 nuclear membrane organization involved in mitotic nuclear division A mitotic cell cycle process which results in the assembly, arrangement, or disassembly of the nuclear inner or outer membrane during mitosis. GO:0101023 vascular endothelial cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0101023 The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population. GO:0101026 mitotic nuclear membrane biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0101026 nuclear membrane biogenesis involved in mitotic nuclear division A process in which the nuclear inner or outer membrane is synthesized, aggregates, and bonds together during mitotic nuclear division. GO:0101025 nuclear membrane biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0101025 The process in which a nuclear membrane is synthesized, aggregates, and bonds together. GO:0101028 positive regulation of liquid surface tension biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0101028 positive regulation of surface tension of a liquid Any process that activates or increases the surface tension of a liquid. GO:0101027 optical nerve axon regeneration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0101027 The regrowth of axons of the optical nerve following their loss or damage. GO:0101029 negative regulation of liquid surface tension biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0101029 negative regulation of surface tension of a liquid Any process that prevents or reduces the surface tension of a liquid. CHEBI:79352 progoitrin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79352 CHEBI:79350 xi-progoitrin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79350 GO:0101031 chaperone complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0101031 A protein complex required for the non-covalent folding or unfolding, maturation, stabilization or assembly or disassembly of macromolecular structures. Usually active during or immediately after completion of translation. Many chaperone complexes contain heat shock proteins. GO:0101030 tRNA-guanine transglycosylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0101030 The modification of a tRNA anticodon loop by replacing guanine with queuonine. Reaction is tRNA guanine + queuine = tRNA queuine + guanine. OBO:GOCHE_24869 substance with ionophore role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_24869 CHEBI:80352 4,4'-Diaponeurosporenic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_80352 CHEBI:79364 indolylmethylglucosinolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79364 UBERON:5102544 individual digit of digitopodial skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_5102544 digit skeleton|digit A subdivision of the skeleton of the autopod consisting of the phalanges of a single digit plus the associated metapodial element. OBO:GOCHE_24874 substance with iron ionophore role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_24874 GO:0042301 phosphate ion binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042301 Interacting selectively and non-covalently with phosphate. GO:0042300 beta-amyrin synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042300 MetaCyc:RXN-7570|EC:5.4.99.- oxidosqualene:beta-amyrin cyclase activity Catalysis of the reaction: (S)-2,3-epoxysqualene = beta-amyrin. This reaction is the cyclization and rearrangement of (S)-2,3-epoxysqualene (2,3-oxidosqualene) into beta-amyrin. GO:0042307 positive regulation of protein import into nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042307 up regulation of protein import into nucleus|activation of protein import into nucleus|positive regulation of protein-nucleus import|stimulation of protein import into nucleus|positive regulation of protein import into cell nucleus|up-regulation of protein import into nucleus|positive regulation of protein transport from cytoplasm to nucleus|upregulation of protein import into nucleus Any process that activates or increases the frequency, rate or extent of movement of proteins from the cytoplasm into the nucleus. GO:0042306 regulation of protein import into nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042306 regulation of protein-nucleus import|regulation of protein transport from cytoplasm to nucleus|regulation of protein import into cell nucleus Any process that modulates the frequency, rate or extent of movement of proteins from the cytoplasm to the nucleus. GO:0042309 homoiothermy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042309 ice nucleation activity|antifreeze activity|ice nucleation inhibitor activity Any homoeostatic process in which an organism maintains its internal body temperature at a relatively constant value. This is achieved by using metabolic processes to counteract fluctuations in the temperature of the environment. GO:0042308 negative regulation of protein import into nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042308 negative regulation of protein import into cell nucleus|down-regulation of protein import into nucleus|inhibition of protein import into nucleus|negative regulation of protein transport from cytoplasm to nucleus|down regulation of protein import into nucleus|downregulation of protein import into nucleus|negative regulation of protein-nucleus import Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus. GO:0042303 molting cycle biolink:BiologicalProcess go-plus goslim_pir|goslim_drosophila http://purl.obolibrary.org/obo/GO_0042303 The periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin, etc. GO:0042302 structural constituent of cuticle biolink:MolecularActivity go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0042302 The action of a molecule that contributes to the structural integrity of a cuticle. GO:0042305 specification of segmental identity, mandibular segment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042305 The specification of the characteristic structures of the mandibular segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized. GO:0042304 regulation of fatty acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042304 regulation of fatty acid anabolism|regulation of fatty acid synthesis|regulation of fatty acid formation|regulation of fatty acid biosynthesis Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. GO:0042310 vasoconstriction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042310 Wikipedia:Vasoconstriction negative regulation of blood vessel size A decrease in the diameter of blood vessels, especially arteries, due to constriction of smooth muscle cells that line the vessels, and usually causing an increase in blood pressure. GO:0042312 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042312 GO:0042311 vasodilation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042311 Wikipedia:Vasodilation vasodilatation|positive regulation of blood vessel size An increase in the internal diameter of blood vessels, especially arterioles or capillaries, due to relaxation of smooth muscle cells that line the vessels, and usually resulting in a decrease in blood pressure. GO:0042318 penicillin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042318 penicillin anabolism|penicillin biosynthesis|penicillin synthesis|penicillin formation The chemical reactions and pathways resulting in the formation of any antibiotic that contains the condensed beta-lactamthiazolidine ring system. GO:0042317 penicillin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042317 penicillin degradation|penicillin breakdown|penicillin catabolism The chemical reactions and pathways resulting in the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system. CHEBI:79380 (2E,4Z)-2-hydroxy-7-methyl-6-oxo-2,4-octadienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79380 GO:0042319 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042319 GO:0042314 bacteriochlorophyll binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042314 Interacting selectively and non-covalently with bacteriochlorophyll, a form of chlorophyll found in photosynthetic bacteria, such as the purple and green bacteria. There are several types, designated a to g. Bacteriochlorophyll a and bacteriochlorophyll b are structurally similar to the chlorophyll a and chlorophyll b found in plants. GO:0042313 protein kinase C deactivation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042313 PKC deactivation Any process resulting in the inhibition or termination of the activity of protein kinase C. GO:0042316 penicillin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042316 penicillin metabolism The chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system. Penicillins are produced naturally during the growth of various microfungi of the genera Penicillium and Aspergillus. GO:0042315 obsolete cytosol nonspecific dipeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042315 iminodipeptidase activity|glycyl-glycine dipeptidase activity|glycylleucine peptidase activity|L-prolylglycine dipeptidase activity|glycylleucine dipeptide hydrolase activity|diglycinase activity|Gly-Leu hydrolase activity|glycyl-leucine dipeptidase activity|N2-beta-alanylarginine dipeptidase activity|N(2)-beta-alanylarginine dipeptidase activity|prolyl dipeptidase activity|cytosol nonspecific dipeptidase activity|glycyl-L-leucine hydrolase activity|prolinase activity|human cytosolic non-specific dipeptidase activity|peptidase A activity|glycyl-L-leucine dipeptidase activity|Pro-X dipeptidase activity|glycyl-L-leucine peptidase activity|non-specific dipeptidase activity|L-amino-acyl-L-amino-acid hydrolase activity|cytosol non-specific dipeptidase activity|glycylleucine hydrolase activity|prolylglycine dipeptidase activity OBSOLETE. Catalysis of the hydrolysis of dipeptides, preferentially hydrophobic dipeptides including prolyl amino acids. CHEBI:79383 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79383 CHEBI:3095 biguanide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_3095 CHEBI:79389 monovalent inorganic anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79389 CHEBI:79388 divalent inorganic anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79388 CHEBI:79387 trivalent inorganic anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79387 CHEBI:3098 bile acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_3098 GO:0042321 negative regulation of circadian sleep/wake cycle, sleep biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042321 down regulation of circadian sleep/wake cycle, sleep|downregulation of circadian sleep/wake cycle, sleep|down-regulation of circadian sleep/wake cycle, sleep|negative regulation of sleep|inhibition of circadian sleep/wake cycle, sleep Any process that stops, prevents or reduces the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals. GO:0042320 regulation of circadian sleep/wake cycle, REM sleep biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042320 regulation of REM sleep Any process that modulates the frequency, rate or extent of rapid eye movement (REM) sleep. GO:0042323 negative regulation of circadian sleep/wake cycle, non-REM sleep biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042323 negative regulation of non-REM sleep|inhibition of circadian sleep/wake cycle, non-REM sleep|down regulation of circadian sleep/wake cycle, non-REM sleep|downregulation of circadian sleep/wake cycle, non-REM sleep|down-regulation of circadian sleep/wake cycle, non-REM sleep Any process that stops, prevents or reduces the duration or quality of non-rapid eye movement (NREM) sleep. GO:0042322 negative regulation of circadian sleep/wake cycle, REM sleep biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042322 inhibition of circadian sleep/wake cycle, REM sleep|negative regulation of REM sleep|down regulation of circadian sleep/wake cycle, REM sleep|downregulation of circadian sleep/wake cycle, REM sleep|down-regulation of circadian sleep/wake cycle, REM sleep Any process that stops, prevents or reduces the duration or quality of rapid eye movement (REM) sleep. GO:0042329 structural constituent of collagen and cuticulin-based cuticle biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042329 structural constituent of cuticle The action of a molecule that contributes to the structural integrity of a collagen and cuticulin-based cuticle. An example of this process is found in Caenorhabditis elegans. CHEBI:79392 EC 6.1.1.2 (tryptophan--tRNA ligase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79392 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042328 heparan sulphate N-acetylglucosaminyltransferase activity|heparin N-acetylglucosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + heparan sulfate = UDP + (N-acetyl-D-glucosaminyl)-heparan sulfate. GO:0042325 regulation of phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042325 Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule. GO:0042324 hypocretin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042324 orexin receptor ligand|hypocretin receptor ligand|orexin receptor binding Interacting selectively and non-covalently with the hypocretin receptor. GO:0042327 positive regulation of phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042327 up regulation of phosphorylation|activation of phosphorylation|stimulation of phosphorylation|up-regulation of phosphorylation|upregulation of phosphorylation Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule. GO:0042326 negative regulation of phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042326 down-regulation of phosphorylation|inhibition of phosphorylation|down regulation of phosphorylation|downregulation of phosphorylation Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule. CHEBI:79394 indolmycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79394 PR:000016052 antigen peptide transporter 2 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000016052 histocompatibility antigen modifier 2|Ham-2|Y1|peptide transporter involved in antigen processing 2|really interesting new gene 11 protein|TAP2|ABCB3|APT2|RING11|PSF2|peptide transporter PSF2|PSF-2|peptide transporter TAP2|peptide supply factor 2|ATP-binding cassette sub-family B member 3|Ham2 A protein that is a translation product of the human TAP2 gene or a 1:1 ortholog thereof. PR:000016051 antigen peptide transporter 1 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000016051 Ham1|histocompatibility antigen modifier 1|Y3|Ham-1|peptide transporter involved in antigen processing 1|TAP1|ABCB2|APT1|PSF1|really interesting new gene 4 protein|peptide transporter TAP1|PSF-1|peptide transporter PSF1|ATP-binding cassette sub-family B member 2|peptide supply factor 1|RING4 A protein that is a translation product of the human TAP1 gene or a 1:1 ortholog thereof. PR:000016053 tapasin biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000016053 NGS-17|TAPA|TPSN|TAP-associated protein|TPN|TAPBP|TAP-binding protein|NGS17 A protein that is a translation product of the human TAPBP gene or a 1:1 ortholog thereof. GO:0042332 gravitaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042332 gravitactic behaviour|taxis in response to gravitational stimulus|taxis in response to gravity|gravitactic behavior|geotactic behavior|geotactic behaviour|geotaxis The directed movement of a motile cell or organism in response to gravity. GO:0042331 phototaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042331 Wikipedia:Phototaxis taxis in response to light|phototactic behavior|phototactic behaviour The directed movement of a motile cell or organism in response to light. GO:0042334 taxis to electron acceptor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042334 taxis in response to electron acceptor The directed movement of a motile cell or organism in response to the presence of an alternative electron acceptor, for example, nitrate. GO:0042333 chemotaxis to oxidizable substrate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042333 taxis in response to oxidizable substrate The directed movement of a motile cell or organism in response to the presence of an oxidizable substrate, for example, fructose. GO:0042330 taxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042330 Wikipedia:Taxis directed movement in response to stimulus The directed movement of a motile cell or organism in response to an external stimulus. GO:0042339 keratan sulfate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042339 keratan sulphate metabolic process|keratan sulfate metabolism|keratan sulphate metabolism The chemical reactions and pathways involving keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues. GO:0042336 obsolete cuticle development involved in protein-based cuticle molting cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042336 cuticle anabolism during molting|cuticle biosynthetic process during molting|cuticle development involved in protein-based cuticle molting cycle|cuticle formation during molting|cuticle synthesis during molting OBSOLETE. Synthesis and deposition of a protein-based noncellular, hardened, or membranous secretion from an epithelial sheet, occurring as part of the molting cycle. Examples of this process are found in invertebrate species. GO:0042335 cuticle development biolink:BiologicalProcess go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0042335 cuticle biosynthesis|cuticle biosynthetic process|cuticle anabolism|cuticle synthesis|cuticle formation The chemical reactions and pathways resulting in the formation of a cuticle, the outer layer of some animals and plants, which acts to prevent water loss. GO:0042338 cuticle development involved in collagen and cuticulin-based cuticle molting cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042338 cuticle anabolism during molting|collagen and cuticulin-based cuticle development during molting|cuticle biosynthetic process during molting|cuticle formation during molting|cuticle synthesis during molting Synthesis and deposition of a collagen and cuticulin-based noncellular, hardened, or membranous secretion from an epithelial sheet, occurring as part of the molting cycle. An example of this process is found in Caenorhabditis elegans. GO:0042337 cuticle development involved in chitin-based cuticle molting cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042337 cuticle anabolism during molting|cuticle biosynthetic process during molting|chitin-based cuticle development during molting|cuticle formation during molting|cuticle synthesis during molting The synthesis and deposition of a chitin-based non-cellular, hardened, or membranous secretion from an epithelial sheet, occurring as part of the molting cycle. An example of this is found in Drosophila melanogaster. GO:0101002 ficolin-1-rich granule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0101002 ficolin-1 rich granule|ficolin granule Highly exocytosable gelatinase-poor granules found in neutrophils and rich in ficolin-1. Ficolin-1 is released from neutrophil granules by stimulation with fMLP or PMA, and the majority becomes associated with the surface membrane of the cells and can be detected by flow cytometry. GO:0042343 indole glucosinolate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042343 indole glucosinolate metabolism The chemical reactions and pathways resulting in the formation of indole glucosinolates. Glucosinolates are sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan; indoles are biologically active substances based on 2,3-benzopyrrole, formed during the catabolism of tryptophan. GO:0042342 cyanogenic glycoside catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042342 cyanogenic glycoside degradation|cyanogenic glycoside catabolism|cyanogenic glycoside breakdown The chemical reactions and pathways resulting in the breakdown of cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits. GO:0101004 cytolytic granule membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0101004 The lipid bilayer surrounding the cytolytic granule. GO:0042345 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042345 GO:0042344 indole glucosinolate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042344 indole glucosinolate catabolism|indole glucosinolate degradation|indole glucosinolate breakdown The chemical reactions and pathways resulting in the breakdown of indole glucosinolates, sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan. GO:0101003 ficolin-1-rich granule membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0101003 The lipid bilayer surrounding a ficolin-1-rich granule. GO:0101006 protein histidine phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0101006 phosphohistidine phosphatase activity Catalysis of the reaction: protein histidine phosphate + H2O = protein histidine + phosphate. GO:0101005 ubiquitinyl hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0101005 Reactome:R-HSA-9674127 deubiquitinase activity|ubiquitin-specific protease activity involved in negative regulation of retrograde protein transport, ER to cytosol Catalysis of the hydrolysis of ubiquitin from proteins and other molecules. GO:0101008 obsolete negative regulation of transcription from RNA polymerase II promoter in response to increased salt biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0101008 OBSOLETE. Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. GO:0042341 cyanogenic glycoside metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042341 cyanogenic glycoside metabolism The chemical reactions and pathways involving cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits. GO:0101007 obsolete negative regulation of transcription from RNA polymerase II promoter in response to salt stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0101007 OBSOLETE. Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under salt stress. The stress is usually an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. GO:0042340 keratan sulfate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042340 keratan sulfate catabolism|keratan sulphate catabolism|keratan sulphate catabolic process|keratan sulfate degradation|keratan sulfate breakdown The chemical reactions and pathways resulting in the breakdown of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues. GO:0042347 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042347 GO:0042346 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042346 GO:0042349 guiding stereospecific synthesis activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042349 dirigent protein The orientation of free radical substrates in such a way that only a particular stereoisomer is synthesized by an enzyme. Best characterized as a function during lignan biosynthesis. GO:0042348 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042348 GO:0101011 inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate 1-diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0101011 inositol 1-pyrophosphate 2,3,4,5,6-pentakisphosphate 1-pyrophosphatase activity Catalysis of the reaction: myo-inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate + H2O = myo-inositol hexakisphosphate + phosphate. GO:0101010 pulmonary blood vessel remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0101010 The reorganization or renovation of existing pulmonary blood vessels. GO:0042354 L-fucose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042354 L-fucose metabolism The chemical reactions and pathways involving L-fucose, 6-deoxy-L-galactose, a sugar that occurs in fucans, a class of polysaccharides in seaweeds, especially Fucus species, and in the cell wall matrix of higher plants. GO:0101013 mechanosensitive voltage-gated sodium channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0101013 mechanically-modulated voltage-gated sodium channel activity Enables the transmembrane transfer of a sodium ion by a voltage-gated channel whose activity is modulated in response to mechanical stress. Response to mechanical stress and voltage gating together is different than the sum of individual responses. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. GO:0042353 fucose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042353 fucose anabolism|fucose synthesis|fucose biosynthesis|fucose formation The chemical reactions and pathways resulting in the formation of fucose (6-deoxygalactose). GO:0101012 inositol 1,5-bisdiphosphate 2,3,4,6-tetrakisphosphate 1-diphosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0101012 inositol 1,5-bispyrophosphate 2,3,4,6-tetrakisphosphate 1-pyrophosphatase activity Catalysis of the reaction: myo-inositol 1,5-bisdiphosphate 2,3,4,6-tetrakisphosphate + H2O = myo-inositol 5-diphosphate 1,2,3,4,6-pentakisphosphate + phosphate. GO:0042356 GDP-4-dehydro-D-rhamnose reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042356 EC:1.1.1.187|MetaCyc:GDP-4-DEHYDRO-D-RHAMNOSE-REDUCTASE-RXN GDP-4-keto-D-rhamnose reductase activity|guanosine diphosphate-4-keto-D-rhamnose reductase activity|GDP-4-keto-6-deoxy-D-mannose reductase activity|GDP-6-deoxy-D-mannose:NAD(P)+ 4-oxidoreductase activity Catalysis of the reaction: GDP-6-deoxy-D-mannose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-mannose + NAD(P)H + H+. In the reverse reaction, a mixture of GDP-D-rhamnose and its C-4 epimer is formed. GO:0101014 [isocitrate dehydrogenase (NADP+)] phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0101014 MetaCyc:ICITDEHASE-KIN-PHOSPHA isocitrate dehydrogenase kinase/phosphatase activity Catalysis of the reaction: [isocitrate dehydrogenase] phosphate + H2O = [isocitrate dehydrogenase] + phosphate. GO:0042355 L-fucose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042355 L-fucose degradation|L-fucose breakdown|L-fucose catabolism The chemical reactions and pathways resulting in the breakdown of L-fucose (6-deoxy-Lgalactose). GO:0042350 GDP-L-fucose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042350 GDP-L-fucose synthesis|GDP-L-fucose formation|GDP-L-fucose biosynthesis|GDP-L-fucose anabolism The chemical reactions and pathways resulting in the formation of GDP-L-fucose, a substance composed of L-fucose in glycosidic linkage with guanosine diphosphate. GO:0101017 regulation of mitotic DNA replication initiation from late origin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0101017 regulation of late replication origin firing Any process that modulates the frequency, rate or extent of firing from a late origin of replication involved in mitotic DNA replication. GO:0101016 FMN-binding domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0101016 Interacting selectively and non-covalently with the FMN-binding domain of a protein. GO:0042352 GDP-L-fucose salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042352 MetaCyc:PWY-6 GDP-L-fucose biosynthetic process, salvage pathway|GDP-L-fucose biosynthesis, salvage pathway The formation of GDP-L-fucose from L-fucose, without de novo synthesis. L-fucose is phosphorylated by fucokinase and then converted by fucose-1-phosphate guanylyltransferase (EC:2.7.7.30). GO:0101019 nucleolar exosome (RNase complex) biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0101019 A ribonuclease complex that has 3-prime to 5-prime distributive hydrolytic exoribonuclease activity and in some taxa (e.g. yeast) endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured. GO:0042351 'de novo' GDP-L-fucose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042351 MetaCyc:PWY-66 'de novo' GDP-L-fucose biosynthesis|GDP-L-fucose biosynthetic process, de novo pathway|'de novo' GDP-L-fucose anabolism|GDP-L-fucose biosynthesis, de novo pathway|'de novo' GDP-L-fucose synthesis|'de novo' GDP-L-fucose formation The chemical reactions and pathways resulting in the formation of GDP-L-fucose from GDP-D-mannose via GDP-4-dehydro-6-deoxy-D-mannose, requiring the functions of GDP-mannose 4,6-dehydratase (EC:4.2.1.47) and GDP-L-fucose synthase (EC:1.1.1.271). GO:0101018 negative regulation of mitotic DNA replication initiation from late origin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0101018 negative regulation of late replication origin firing Any process that stops, prevents or reduces the frequency, rate or extent of firing from a late origin of replication involved in mitotic DNA replication. GO:0042358 thiamine diphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042358 thiamin diphosphate breakdown|thiamin diphosphate catabolic process|thiamin pyrophosphate catabolic process|TPP catabolism|thiamine pyrophosphate catabolism|thiamine diphosphate catabolism|thiamine pyrophosphate catabolic process|thiamin pyrophosphate catabolism|TPP catabolic process|thiamin diphosphate catabolism|thiamin diphosphate degradation The chemical reactions and pathways resulting in the breakdown of thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle. GO:0042357 thiamine diphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042357 thiamine pyrophosphate metabolic process|TPP metabolic process|TPP metabolism|thiamine pyrophosphate metabolism|thiamine diphosphate metabolism|thiamin pyrophosphate metabolism|thiamin diphosphate metabolism|thiamin diphosphate metabolic process|thiamin pyrophosphate metabolic process The chemical reactions and pathways involving thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle. GO:0042359 vitamin D metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042359 ergocalciferol metabolism|ergocalciferol metabolic process|vitamin D metabolism|calciferol metabolism|cholecalciferol metabolism|cholecalciferol metabolic process|calciferol metabolic process The chemical reactions and pathways involving vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3). OBO:GOCHE_24852 substance with insecticide role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_24852 GO:0150035 regulation of trans-synaptic signaling by BDNF, modulating synaptic transmission biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0150035 Any process that modulates the frequency, rate or extent of trans-synaptic signaling by BDNF, modulating synaptic transmission. GO:0150034 distal axon biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0150034 distal part of the axon|distal part of axon That part of an axon close to and including the growth cone or the axon terminus. GO:0150033 negative regulation of protein localization to lysosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150033 Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to lysosome. GO:0150032 positive regulation of protein localization to lysosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150032 Any process that activates or increases the frequency, rate or extent of protein localization to lysosome. GO:0150031 regulation of protein localization to lysosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150031 Any process that modulates the frequency, rate or extent of protein localization to lysosome. GO:0150038 postsynaptic dense core vesicle exocytosis biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0150038 The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a postsynaptic dense core vesicle by fusion of the granule with the plasma membrane of the postsynapse in response to increased cytosolic calcium levels. GO:0150037 regulation of calcium-dependent activation of synaptic vesicle fusion biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0150037 Any process that modulates the frequency, rate or extent of calcium-dependent activation of synaptic vesicle fusion. GO:0150036 regulation of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0150036 Any process that modulates the frequency, rate or extent of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission. CHEBI:31334 (E)-caffeyl alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_31334 GO:0150045 regulation of synaptic signaling by nitric oxide biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0150045 Any process that modulates the frequency, rate or extent of synaptic signaling by nitric oxide. GO:0150044 regulation of postsynaptic dense core vesicle exocytosis biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0150044 Any process that modulates the frequency, rate or extent of postsynaptic dense core vesicle exocytosis. GO:0150043 structural constituent of synapse-associated extracellular matrix biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0150043 structural constituent of extra-synaptic extracellular matrix|synapse-associated extracellular matrix structural constituent|extra-synaptic extracellular matrix structural constituent The action of a molecule that contributes to the structural integrity of the extracellular matrix of the perisynaptic space (the extracellular space adjacent to the synapse) and the synaptic cleft. CHEBI:137706 17-epiestriol 16-O-(beta-D-glucuronide) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137706 CHEBI:137701 17-epiestriol 3-O-(beta-D-glucuronide) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137701 UBERON:0006794 visual processing part of nervous system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006794 optic lobe CHEBI:137700 3-carboxy-3-hydroxypropanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137700 UBERON:0006793 deep layer of superior colliculus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006793 superior colliculus, deep layer The innermost layer of the superior colliculus. UBERON:0006792 intermediate layer of superior colliculus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006792 central zone|superior colliculus, intermediate layer|superior colliculus, central layer|central zone of the optic tectum A layer of superior colliculus that lies between the superficial layer and the deep layer. UBERON:0006791 superficial layer of superior colliculus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006791 superficial grey and white zones|superior colliculus, superficial layer|superficial gray and white zone|superficial grey and white zone The outermost layer of the superior colliculus. CHEBI:45979 thiabendazole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_45979 GO:0150048 cerebellar granule cell to Purkinje cell synapse biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0150048 cerebellar parallel fiber to Purkinje cell synapse A synapse of a granule cell fiber onto the dendrites of a Purkinje cell in cerebellum. GO:0150047 G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential biolink:MolecularActivity go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0150047 G-protein coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential G protein-coupled neurotransmitter receptor activity, occurring in the presynaptic membrane, involved in regulation of presynaptic membrane potential. CHEBI:137702 17-epiestriol 17-O-(beta-D-glucuronide) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137702 UBERON:0006799 glandular epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006799 An epithelium that is composed primarily of secretory cells. CHEBI:21990 O(4')-glycosyl-L-tyrosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21990 CHEBI:21993 O(4)-glycosyl-L-hydroxyproline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21993 GO:0150013 negative regulation of neuron projection arborization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150013 negative regulation of neuron projection branching|negative regulation of neurite branching|negative regulation of neurite arborization Any process that stops, prevents or reduces the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches. GO:0150012 positive regulation of neuron projection arborization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150012 positive regulation of neurite branching|positive regulation of neurite arborization|positive regulation of neuron projection branching Any process that activates or increases the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches. GO:0150011 regulation of neuron projection arborization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150011 regulation of neurite arborization|regulation of neurite branching|regulation of neuron projection branching Any process that modulates the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches. UBERON:0006783 layer of superior colliculus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006783 cytoarchitectural part of superior colliculus|tectal layer|layer of optic tectum The microstructure of the optic tectum / superior colliculus varies across species. As a general rule, there is always a clear distinction between superficial layers, which receive input primarily from the visual system and show primarily visual responses, and deeper layers, which receive many types of input and project to numerous motor-related brain areas. The distinction between these two zones is so clear and consistent that some anatomists have suggested that they should be considered separate brain structures. In mammals, neuroanatomists conventionally identify seven layers[WP]. GO:0150019 basal dendrite morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150019 The process in which the anatomical structures of a basal dendrite are generated and organized. GO:0150018 basal dendrite development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150018 The process whose specific outcome is the progression of a basal dendrite over time, from its formation to the mature structure. GO:0150017 basal proximal dendrite biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0150017 Any dendrite in a dendritic tree that emerges near the basal pole of a neuron (e.g. in bipolar neurons, basal dendrites are either on the same side of the soma as the axon, or project toward the axon), and which is the closest to the cell body of the neuron (the soma). CHEBI:45969 tricarballylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_45969 CHEBI:70968 15-methylhexadecaphytosphingosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70968 GO:0150016 basal distal dendrite biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0150016 Any dendrite in a dendritic tree that emerges near the basal pole of a neuron (e.g. in bipolar neurons, basal dendrites are either on the same side of the soma as the axon, or project toward the axon), and which is farthest away from the neuronal cell body (the soma). GO:0150015 apical proximal dendrite biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0150015 The dendrite of the dendritic tree, which emerges near the apical pole of a neuron, and which is the closest to the cell body of the neuron (the soma). GO:0150014 apical distal dendrite biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0150014 Any dendrite in a dendritic tree that emerges near the apical pole of a neuron, and which is farthest away from the neuronal cell body (the soma). CHEBI:70964 8-hydroxy-dAMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70964 CHEBI:70963 8-hydroxy-dADP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70963 UBERON:0006786 white matter of superior colliculus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006786 white matter layer of superior colliculus|predominantly white regional part of superior colliculus A central nervous system white matter layer that is part of a superior colliculus. UBERON:0006785 gray matter layer of superior colliculus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006785 gray matter of superior colliculus A central nervous system gray matter layer that is part of a superior colliculus. CHEBI:79308 1-oleyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79308 GO:0150024 oxidised low-density lipoprotein particle clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150024 oxidised LDL particle clearance|oxidized LDL particle clearance|oxidized low-density lipoprotein particle clearance|oxLDL particle clearance|ox-LDL particle clearance The process in which an oxidised low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. GO:0150023 apical dendrite arborization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150023 The process in which the anatomical structures of a dendritic tree are generated on the apical neuron side and organized into dendritic branches. GO:0150022 apical dendrite development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150022 The process whose specific outcome is the progression of an apical dendrite over time, from its formation to the mature structure. GO:0150021 apical dendrite morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150021 The process in which the anatomical structures of an apical dendrite are generated and organized. GO:0150020 basal dendrite arborization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150020 The process in which the anatomical structures of a dendritic tree are generated on the basal neuron side and organized into dendritic branches. CHEBI:45956 tristearoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_45956 GO:0150025 oxidised low-density lipoprotein particle receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0150025 oxLDL particle receptor activity|ox-LDL particle receptor activity|ox-LDL receptor activity|oxLDL receptor activity|oxidised LDL particle receptor activity|oxidized low-density lipoprotein receptor activity|oxidized LDL receptor activity|oxidised low-density lipoprotein receptor activity|oxidized LDL particle receptor activity|oxidised LDL receptor activity|oxidized low-density lipoprotein particle receptor activity Combining with an oxidised low-density lipoprotein particle and delivering the oxidised low-density lipoprotein particle into the cell via endocytosis. CHEBI:70977 alkane-alpha,omega-diammonium(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70977 CHEBI:70975 heparan sulfate alpha-D-glucosaminide 3-sulfate polyanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70975 CHEBI:70974 heparan sulfate N-acetyl-alpha-D-glucosaminide polyanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70974 UBERON:0006777 tectal plate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006777 quadrigeminal plate|lamina quadrigemina embryologic structure that is formed by two longitudinal eminences, one on each alar plate of the midbrain. These eminences become the superior colliculus and inferior colliculus ( Carpenter-1983 )] CHEBI:79319 gluconapin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79319 CHEBI:80308 Substance P biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_80308 CHEBI:70988 N-monoacetylalkane-alpha,omega-diamine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70988 CHEBI:21976 o-succinylhomoserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21976 CHEBI:79313 glycosinolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79313 CHEBI:79312 18-hydroxyoleic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79312 CHEBI:21977 O-(N-acetylglucosamine-1-phosphoryl)-L-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21977 CHEBI:70983 4-hydroxy-15-methylhexadecasphinganine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70983 CHEBI:79316 glucosinolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79316 NCBITaxon:8782 Aves organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_8782 avian|birds|birds CHEBI:79315 alkenylglucosinolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79315 CHEBI:79314 flame retardant biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79314 CHEBI:70980 (R)-lactoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70980 CHEBI:70990 3-hydroxyadipyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70990 GO:0150002 distal dendrite biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0150002 The dendrite of the dendritic tree that is farthest away from the neuronal cell body (the soma). CHEBI:45931 thiamine(1+) diphosphate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_45931 GO:0150001 primary dendrite biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0150001 A dendrite emerging from the cell body (the soma) of a neuron. GO:0150008 bulk synaptic vesicle endocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150008 bulk endocytosis|activity-dependent bulk endocytosis|ADBE|activity-dependent bulk synaptic vesicle endocytosis Endocytosis of large regions of presynaptic membrane after intense stimulation-mediated fusion of multiple synaptic vesicles. Bulk endocytosis is triggered by high loads of membrane addition through exocytosis of synaptic vesicles and elevated concentration of calcium in the presynapse. GO:0150007 clathrin-dependent synaptic vesicle endocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150007 Clathrin-dependent endocytosis of presynaptic membrane regions comprising synaptic vesicles' membrane constituents. This is a relatively slow process occurring in the range of tens of seconds. GO:0150006 urease activator complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0150006 IntAct:EBI-16417801 A protein complex required for the activation of urease. Activator subunits dissociate before urease has catalytic function. GO:0150005 enzyme activator complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0150005 IntAct:EBI-16417801 A protein complex capable of activating an enzyme. Activating subunits may dissociate from the catalytic unit before the enzyme is active. GO:0150004 dendritic spine origin biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0150004 The part of the dendritic spine neck where the spine arises from the dendritic shaft. GO:0150003 regulation of spontaneous synaptic transmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150003 Any process that modulates the frequency, rate or extent of spontaneous synaptic transmission. CHEBI:70998 G-protein-coupled receptor agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70998 CHEBI:79322 thia-alkylglucosinolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79322 CHEBI:70995 trans-13-methyltetradec-2-enal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70995 CHEBI:70994 hexacyclic triterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70994 CHEBI:79327 alkylglucosinolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79327 CHEBI:70991 15-methylhexadecasphing-4-enine 1-phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70991 CHEBI:79333 3'-(D-alpha-aminoacyl)adenylyl zwitterionic group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79333 CHEBI:79332 1-alkyl-2-acyl-3-(3-O-sulfo-beta-D-galactosyl)-sn-glycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79332 CHEBI:21958 O-glycosyl-L-threonine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21958 CHEBI:21957 O-glycosyl-L-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21957 CHEBI:79337 1,2-diacyl-3-(3-O-sulfo-beta-D-galactosyl)glycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79337 CHEBI:79342 aralkylglucosinolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79342 CHEBI:45912 D-threonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_45912 CHEBI:79346 anionic ganglioside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79346 CHEBI:21969 O-phosphorylhomoserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21969 CHEBI:21968 O-phosphoamino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21968 CHEBI:79348 hydroxy-alkenylglucosinolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79348 GO:0032959 inositol trisphosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032959 inositol trisphosphate synthesis|inositol trisphosphate formation|inositol trisphosphate biosynthesis|myo-inositol trisphosphate biosynthetic process|IP3 biosynthetic process|IP3 biosynthesis|inositol trisphosphate anabolism The chemical reactions and pathways resulting in the formation of inositol trisphosphate, 1,2,3,4,5,6-cyclohexanehexol, with three phosphate groups attached. GO:0032958 inositol phosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032958 myo-inositol phosphate biosynthetic process|inositol phosphate anabolism|inositol phosphate synthesis|inositol phosphate formation|inositol phosphate biosynthesis The chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached. GO:0032957 inositol trisphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032957 myo-inositol trisphosphate metabolic process|IP3 metabolic process|inositol trisphosphate metabolism|IP3 metabolism The chemical reactions and pathways involving myo-inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with three phosphate groups attached. GO:0032956 regulation of actin cytoskeleton organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032956 regulation of actin cytoskeleton organization and biogenesis|regulation of actin cytoskeleton organisation Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. GO:0032955 regulation of division septum assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032955 regulation of division septum formation Any process that modulates the frequency, rate or extent of division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. GO:0032954 regulation of cytokinetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032954 Any process that modulates the frequency, rate or extent of a cytokinetic process. GO:0032953 regulation of (1->3)-beta-D-glucan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032953 regulation of 1,3-beta-glucan biosynthesis|regulation of 1,3-beta-glucan anabolism|regulation of 1,3-beta-glucan biosynthetic process|regulation of 1,3-beta-glucan synthesis|regulation of 1,3-beta-glucan formation Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans. UBERON:0006717 autopodial skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006717 skeleton of autopod|autopod skeleton|skeletal parts of autopod|autopodial skeleton|autopodium The collection of all skeletal elements in an autopodium region. UBERON:0006716 mesopodium region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006716 mesopodial limb segment|carpus/tarsus|mesopodial segment|mesopod The third segment of the limb, including either the wrist segment (carpus) or the ankle segment (tarsus) GO:0032952 regulation of (1->3)-beta-D-glucan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032952 regulation of 1,3-beta-glucan metabolism|regulation of (1->3)-beta-D-glucan metabolism|regulation of 1,3-beta-glucan metabolic process|regulation of 1,3-beta-D-glucan metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-beta-D-glucans. CHEBI:55380 beta-hydroxy ketone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55380 GO:0032951 regulation of beta-glucan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032951 regulation of beta-glucan biosynthesis|regulation of beta-glucan anabolism|regulation of beta-glucan synthesis|regulation of beta-glucan formation Any process that modulates the frequency, rate or extent of the chemical reactions and pathways relusting in the formation of beta-glucans. GO:0032950 regulation of beta-glucan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032950 regulation of beta-glucan metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving beta-glucans. UBERON:0006723 cochlear modiolus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006723 modiolus cochleae|modiolus of cochlea|cochlea modiolus|modiolus|columella cochleae the central cone shaped core of spongy bone about which turns the spiral canal GO:0032948 regulation of alpha-glucan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032948 regulation of alpha-glucan metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving alpha-glucans. GO:0032947 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032947 GO:0032946 positive regulation of mononuclear cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032946 up regulation of mononuclear cell proliferation|positive regulation of peripheral blood mononuclear cell proliferation|upregulation of mononuclear cell proliferation|positive regulation of PBMC proliferation|stimulation of mononuclear cell proliferation|up-regulation of mononuclear cell proliferation|activation of mononuclear cell proliferation Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation. GO:0032945 negative regulation of mononuclear cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032945 negative regulation of peripheral blood mononuclear cell proliferation|negative regulation of PBMC proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of mononuclear cell proliferation. GO:0032944 regulation of mononuclear cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032944 regulation of peripheral blood mononuclear cell proliferation|regulation of PBMC proliferation Any process that modulates the frequency, rate or extent of mononuclear cell proliferation. GO:0032943 mononuclear cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032943 peripheral blood mononuclear cell proliferation|PBMC proliferation The expansion of a mononuclear cell population by cell division. A mononuclear cell is a leukocyte with a single non-segmented nucleus in the mature form. GO:0032942 inositol tetrakisphosphate 2-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032942 EC:2.7.1.- inositol 1,3,4,6-tetrakisphosphate 2-kinase activity|1D-myo-inositol-tetrakisphosphate 2-kinase activity|inositol-tetrakisphosphate 2-kinase activity Catalysis of the reaction: 1D-myo-inositol tetrakisphosphate + ATP = 1D-myo-inositol pentakisphosphate (containing 2-phosphate) + ADP. GO:0032941 secretion by tissue biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032941 tissue secretion|expulsion of gland contents The controlled release of a substance by a tissue. GO:0032949 regulation of alpha-glucan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032949 regulation of alpha-glucan biosynthesis|regulation of alpha-glucan anabolism|regulation of alpha-glucan synthesis|regulation of alpha-glucan formation Any process that modulates the frequency, rate or extent of the chemical reactions and pathways relusting in the formation of alpha-glucans. CHEBI:137789 7,12-dioxolithocholate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137789 CHEBI:55370 imidazolidinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55370 CHEBI:55373 isoxazoles biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55373 GO:0032940 secretion by cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032940 Wikipedia:Secretion cellular secretion The controlled release of a substance by a cell. CHEBI:55377 beta-hematin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_55377 CHEBI:55376 ferriheme b(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_55376 GO:0150093 amyloid-beta clearance by transcytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150093 The process in which amyloid-beta is removed from extracellular brain regions by cell surface receptor-mediated endocytosis, followed by transcytosis across the blood-brain barrier. GO:0032937 SREBP-SCAP-Insig complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032937 A protein complex formed by the association of sterol regulatory element binding protein (SREBP), SREBP-cleavage-activating protein (SCAP), and an Insig protein (Insig-1 or Insig-2) in the ER membrane. GO:0150092 regulation of synaptic scaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150092 regulation of homeostatic synaptic scaling|homeostatic synaptic scaling A process that modulates synaptic scaling. Synaptic scaling is a form of synaptic plasticity, which entails uniform adjustments in the strength of all synapses on a cell in response to prolonged changes in the electrical activity of the cell. GO:0032936 SREBP-SCAP complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032936 Sre1-Scp1 complex A protein complex formed by the association of sterol regulatory element binding protein (SREBP) and SREBP-cleavage-activating protein (SCAP) in the ER membrane; in the absence of sterols, the SREBP-SCAP complex is packaged into COPII vesicles and travels to the Golgi apparatus to be processed. GO:0032935 sterol sensor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032935 sterol-sensing domain Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of a sterol. GO:0150091 multiple spine synapse organization, multiple dendrites biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150091 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse between a multiple synapse bouton and two or more dendritic spines protruding either from a single dendrite or from multiple dendrites. GO:0150090 multiple spine synapse organization, single dendrite biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150090 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse between a multiple synapse bouton and a single dendrite. GO:0032934 sterol binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032934 sterol carrier activity Interacting selectively and non-covalently with a sterol, any steroid containing a hydroxy group in the 3 position, closely related to cholestan-3-ol. GO:0032933 SREBP signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032933 SREBP signalling|sterol regulatory element binding protein target gene transcriptional activation|upregulation of sterol regulatory element binding protein target gene transcription|positive regulation of sterol regulatory element binding protein target gene transcription|positive regulation of sterol regulatory element binding protein target gene transcription involved in sterol depletion response|up regulation of sterol regulatory element binding protein target gene transcription|sterol response element binding protein signaling pathway|activation of sterol regulatory element binding protein target gene transcription|positive regulation of transcription via sterol regulatory element binding involved in ER-nuclear sterol response pathway|positive regulation of transcription via sterol regulatory element binding|stimulation of sterol regulatory element binding protein target gene transcription|endoplasmic reticulum-nuclear sterol response pathway|SREBP-mediated signaling pathway|sterol depletion response, SREBP target gene transcriptional activation|ER-nuclear sterol response pathway|up-regulation of sterol regulatory element binding protein target gene transcription|SREBP target gene transcriptional activation|ER to nucleus sterol response pathway|SREBP-mediated signalling pathway|endoplasmic reticulum to nucleus sterol response pathway A series of molecular signals from the endoplasmic reticulum to the nucleus generated as a consequence of decreased levels of one or more sterols (and in some yeast, changes in oxygen levels) and which proceeds through activation of a sterol response element binding transcription factor (SREBP) to result in up-regulation of target gene transcription. GO:0032932 negative regulation of astral microtubule depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032932 astral microtubule stabilization Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of astral microtubules. GO:0032931 histone acetyltransferase activity (H3-K56 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032931 histone lysine N-acetyltransferase activity (H3-K56 specific) Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 56) = CoA + histone H3 N6-acetyl-L-lysine (position 56). GO:0032930 positive regulation of superoxide anion generation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032930 upregulation of superoxide release|stimulation of superoxide release|activation of superoxide release|positive regulation of superoxide release|up-regulation of superoxide release|up regulation of superoxide release Any process that activates or increases the frequency, rate or extent of enzymatic generation of superoxide by a cell. GO:0150099 neuron-glial cell signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150099 neurone-glia signaling|neuron-glia signaling|neuron-glial cell signalling|neurone-glial cell signalling|neurone-glial cell signaling|neuron-glia signalling|neurone-glia signalling Cell-cell signaling that mediates the transfer of information from a neuron to a glial cell. This signalling has been shown to be mediated by various molecules released by different types of neurons, e.g. glutamate, gamma-amino butyric acid (GABA), noradrenaline, acetylcholine, dopamine and adenosine. GO:0150098 glial cell-neuron signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150098 glial cell-neurone signalling|glial cell- neuron signalling|glial cell-neurone singaling|glia-neuron signaling|glia-neurone signaling|glia-neurone signalling|glia-neuron signalling Cell-cell signaling that mediates the transfer of information from a glial cell to a neuron. This signaling has been shown to be mediated by various molecules, depending on which glial cells release them, and in which tissues the signalling occurs, e.g. microglial cell-derived nerve growth factor (NGF) in the retina, or microglial cell-derived superoxide ions in the cerebellum. GO:0032939 positive regulation of translation in response to oxidative stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032939 up-regulation of translation in response to oxidative stress|upregulation of translation in response to oxidative stress|up regulation of translation in response to oxidative stress|activation of translation in response to oxidative stress|stimulation of translation in response to oxidative stress Any process that activates or increases the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. GO:0150094 amyloid-beta clearance by cellular catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150094 amyloid-beta clearance by phagocytosis The process in which amyloid-beta is removed from extracellular brain regions by cell surface receptor-mediated endocytosis, followed by intracellular degradation. GO:0032938 negative regulation of translation in response to oxidative stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032938 Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. CHEBI:55360 beta-alaninamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55360 CHEBI:55367 deoxyribonucleotide residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55367 CHEBI:55366 ribonucleotide residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55366 GO:0032926 negative regulation of activin receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032926 down regulation of activin receptor signaling pathway|inhibition of activin receptor signaling pathway|negative regulation of activin signaling pathway|negative regulation of activin signalling pathway|down-regulation of activin receptor signaling pathway|negative regulation of activin receptor signalling pathway|downregulation of activin receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any activin receptor signaling pathway. GO:0032925 regulation of activin receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032925 regulation of activin signaling pathway|regulation of activin receptor signalling pathway|regulation of activin signalling pathway Any process that modulates the frequency, rate or extent of the activity of any activin receptor signaling pathway. GO:0032924 activin receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032924 activin receptor signalling pathway A series of molecular signals initiated by the binding of an extracellular ligand to an activin receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0032923 organic phosphonate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032923 organophosphonate biosynthetic process The chemical reactions and pathways resulting in the formation of phosphonates, any organic compound containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Synthesis of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included. GO:0032922 circadian regulation of gene expression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032922 diurnal variation of gene expression|circadian regulation of protein expression|diurnal variation of protein expression Any process that modulates the frequency, rate or extent of gene expression such that an expression pattern recurs with a regularity of approximately 24 hours. GO:0032921 sarcosine oxidase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032921 A complex consisting of 4 protein subunits as a heterotetramer, that possesses sarcosine oxidase activity. GO:0032920 putrescine acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032920 The modification of putrescine by addition of acetyl groups. GO:0032929 negative regulation of superoxide anion generation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032929 down-regulation of superoxide release|downregulation of superoxide release|down regulation of superoxide release|inhibition of superoxide release|negative regulation of superoxide release Any process that stops, prevents, or reduces the frequency, rate or extent of enzymatic generation of superoxide by a cell. GO:0032928 regulation of superoxide anion generation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032928 regulation of superoxide release Any process that modulates the frequency, rate or extent of enzymatic generation of superoxide by a cell. GO:0032927 positive regulation of activin receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032927 upregulation of activin receptor signaling pathway|positive regulation of activin signaling pathway|stimulation of activin receptor signaling pathway|up-regulation of activin receptor signaling pathway|activation of activin receptor signaling pathway|positive regulation of activin signalling pathway|positive regulation of activin receptor signalling pathway|up regulation of activin receptor signaling pathway Any process that activates or increases the frequency, rate or extent of the activity of any activin receptor signaling pathway. CHEBI:55357 (R)-piperazine-2-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55357 CHEBI:55356 (R)-piperazine-2-carboxamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55356 CHEBI:55359 (R)-N-tert-butylpiperazine-2-carboxamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55359 CHEBI:55358 (R)-piperazine-2-carboxylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55358 CHEBI:55353 (2E)-but-2-ene-1,2,3-tricarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55353 CHEBI:55355 7-chloro-D-tryptophan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55355 CHEBI:55354 7-chlorotryptophan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55354 GO:0032915 positive regulation of transforming growth factor beta2 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032915 up-regulation of transforming growth factor-beta2 production|positive regulation of transforming growth factor-beta2 production|upregulation of transforming growth factor-beta2 production|positive regulation of TGF-B2 production|positive regulation of TGFB2 production|up regulation of transforming growth factor-beta2 production|activation of transforming growth factor-beta2 production|stimulation of transforming growth factor-beta2 production Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta2. GO:0150071 negative regulation of arginase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150071 Any process that stops, prevents or reduces the frequency, rate or extent of arginase activity. GO:0150070 regulation of arginase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150070 Any process that modulates the frequency, rate or extent of arginase activity. GO:0032914 positive regulation of transforming growth factor beta1 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032914 activation of transforming growth factor-beta1 production|upregulation of transforming growth factor-beta1 production|positive regulation of TGF-B1 production|positive regulation of TGFB1 production|up regulation of transforming growth factor-beta1 production|stimulation of transforming growth factor-beta1 production|up-regulation of transforming growth factor-beta1 production Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta1. GO:0032913 negative regulation of transforming growth factor beta3 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032913 inhibition of transforming growth factor-beta3 production|negative regulation of transforming growth factor-beta3 production|down regulation of transforming growth factor-beta3 production|negative regulation of TGFB3 production|negative regulation of TGF-B3 production|downregulation of transforming growth factor-beta3 production|down-regulation of transforming growth factor-beta3 production Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta3. GO:0032912 negative regulation of transforming growth factor beta2 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032912 negative regulation of transforming growth factor-beta2 production|down regulation of transforming growth factor-beta2 production|negative regulation of TGFB2 production|negative regulation of TGF-B2 production|downregulation of transforming growth factor-beta2 production|down-regulation of transforming growth factor-beta2 production|inhibition of transforming growth factor-beta2 production Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta2. GO:0032911 negative regulation of transforming growth factor beta1 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032911 negative regulation of transforming growth factor-beta1 production|down regulation of transforming growth factor-beta1 production|negative regulation of TGFB1 production|negative regulation of TGF-B1 production|downregulation of transforming growth factor-beta1 production|down-regulation of transforming growth factor-beta1 production|inhibition of transforming growth factor-beta1 production Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta1. GO:0032910 regulation of transforming growth factor beta3 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032910 regulation of TGF-B3 production|regulation of TGFB3 production|regulation of transforming growth factor-beta3 production Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta3. GO:0150079 negative regulation of neuroinflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150079 Any process that stops, prevents or reduces the frequency, rate or extent of neuroinflammatory response. GO:0150078 positive regulation of neuroinflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150078 Any process that activates or increases the frequency, rate or extent of neuroinflammatory response. GO:0150077 regulation of neuroinflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150077 Any process that modulates the frequency, rate or extent of neuroinflammatory response. GO:0150076 neuroinflammatory response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150076 nerve tissue inflammatory response|nervous tissue inflammatory response|neural tissue inflammatory response The immediate defensive reaction by neural vertebrate tissue to infection or injury caused by chemical or physical agents. GO:0150075 negative regulation of protein-glutamine gamma-glutamyltransferase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150075 Any process that stops, prevents or reduces the frequency, rate or extent of protein-glutamine gamma-glutamyltransferase activity. GO:0032919 spermine acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032919 The modification of spermine by addition of acetyl groups. GO:0150074 positive regulation of protein-glutamine gamma-glutamyltransferase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150074 Any process that activates or increases the frequency, rate or extent of protein-glutamine gamma-glutamyltransferase activity. GO:0032918 spermidine acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032918 The modification of spermidine by addition of acetyl groups. GO:0150073 regulation of protein-glutamine gamma-glutamyltransferase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150073 Any process that modulates the frequency, rate or extent of protein-glutamine gamma-glutamyltransferase activity. GO:0032917 polyamine acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032917 The modification of polyamines by addition of acetyl groups. GO:0150072 positive regulation of arginase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150072 Any process that activates or increases the frequency, rate or extent of arginase activity. GO:0032916 positive regulation of transforming growth factor beta3 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032916 up-regulation of transforming growth factor-beta3 production|positive regulation of transforming growth factor-beta3 production|upregulation of transforming growth factor-beta3 production|positive regulation of TGF-B3 production|positive regulation of TGFB3 production|up regulation of transforming growth factor-beta3 production|activation of transforming growth factor-beta3 production|stimulation of transforming growth factor-beta3 production Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta3. UBERON:0006761 corneo-scleral junction biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006761 corneal limbus|corneal-scleral limbus|corneoscleral junction|sclerocorneal junction|limbus corneae|sclerocorneal limbus|limbus corneae|cornea limbus the edge of the cornea where it joins the sclera; the limbus is a common site for the occurrence of corneal epithelial neoplasm CHEBI:137732 5-carboxy-dCMP(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137732 CHEBI:137731 5-formyl-dCMP(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137731 UBERON:0006763 epithelium of conjunctiva biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006763 conjunctiva epithelium|conjunctival epithelium Layer of nonkeratinized squamous epithelium lining the conjunctiva, overlying scleral tissue GO:0032904 negative regulation of nerve growth factor production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032904 negative regulation of NGF production|down-regulation of nerve growth factor production|downregulation of nerve growth factor production|down regulation of nerve growth factor production|inhibition of nerve growth factor production Any process that stops, prevents, or reduces the frequency, rate, or extent of production of nerve growth factor (NGF). GO:0032903 regulation of nerve growth factor production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032903 regulation of beta-nerve growth factor production|regulation of NGF production Any process that modulates the frequency, rate, or extent of production of nerve growth factor (NGF). GO:0032902 nerve growth factor production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032902 NGF production|beta-nerve growth factor production The appearance of nerve growth factor (NGF) due to biosynthesis or secretion by cells in a neuron's target field, resulting in an increase in its intracellular or extracellular levels. GO:0032901 positive regulation of neurotrophin production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032901 up regulation of neurotrophin production|activation of neurotrophin production|stimulation of neurotrophin production|up-regulation of neurotrophin production|upregulation of neurotrophin production Any process that activates or increases the frequency, rate, or extent of production of a neurotrophin. GO:0032900 negative regulation of neurotrophin production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032900 downregulation of neurotrophin production|down-regulation of neurotrophin production|inhibition of neurotrophin production|down regulation of neurotrophin production Any process that stops, prevents, or reduces the frequency, rate, or extent of production of a neurotrophin. GO:0150089 multiple spine synapse organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150089 multi-synaptic organisation|multisynapse organisation|multisynaptic organisation|multiple spine synapse organisation|multi-synaptic organization|multi-synapse organisation|multisynapse organization|multisynaptic organization|multi-synapse organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse between a multiple synapse bouton and one or more dendritic spines. GO:0150088 multiple synapse bouton, contacting multiple dendrites biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0150088 MSB2|type 2 multisynaptic bouton|type 2 multi-synaptic bouton|type 2 multiple-synapse bouton|type 2 multi-synapse bouton|type 2 multisynapse bouton|type 2 multiple spine synapse bouton A single axon terminal bouton making contact onto two or more dendritic spines protruding from multiple dendrites. GO:0150087 multiple synapse bouton, contacting single dendrite biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0150087 MSB1|type 1 multisynaptic bouton|type 1 multi-synaptic bouton|type 1 multi-synapse bouton|type 1 multiple-synapse bouton|type 1 multisynapse bouton|type 1 multiple spine synapse bouton A single axon terminal bouton making contact onto two or more dendritic spines protruding from the same dendrite. GO:0032909 regulation of transforming growth factor beta2 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032909 regulation of TGFB2 production|regulation of transforming growth factor-beta2 production|regulation of TGF-B2 production Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta2. GO:0150086 multiple synapse bouton biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0150086 multi-synaptic bouton|multiple-synapse bouton|MSB|multisynaptic bouton|multisynapse bouton|multi-synapse bouton|multiple synapse|multi-synapse|multiple spine synapse bouton|multisynapse A single axon terminal bouton making contact onto two or more dendritic spines protruding either from a single dendrite or from multiple dendrites. GO:0032908 regulation of transforming growth factor beta1 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032908 regulation of TGFB1 production|regulation of transforming growth factor-beta1 production|regulation of TGF-B1 production Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta1. GO:0032907 transforming growth factor beta3 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032907 TGFB3 production|transforming growth factor-beta3 production|TGF-B3 production The appearance of transforming growth factor-beta3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0032906 transforming growth factor beta2 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032906 TGF-B2 production|TGFB2 production|transforming growth factor-beta2 production The appearance of transforming growth factor-beta2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0032905 transforming growth factor beta1 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032905 TGF-B1 production|TGFB1 production|transforming growth factor-beta1 production The appearance of transforming growth factor-beta1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. CHEBI:137748 UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137748 CHEBI:55335 ternatin C5 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55335 CHEBI:55334 delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55334 UBERON:0006757 lateral lingual swelling biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006757 tuberculum linguale laterale|lateral lingual prominence|tuberculum laterale|lateral swellings During the third week there appears, immediately behind the ventral ends of the two halves of the mandibular arch, a rounded swelling named the tuberculum impar, which was described by His as undergoing enlargement to form the buccal part of the tongue. More recent researches, however, show that this part of the tongue is mainly, if not entirely, developed from a pair of lateral swellings (or distal tongue bud) which rise from the inner surface of the mandibular arch and meet in the middle line. CHEBI:55337 all-trans-polyprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55337 CHEBI:55336 delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside-3'-O-beta-D-glucoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55336 UBERON:0006756 median lingual swelling biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006756 tuberculum linguale mediale|median lingual swelling|median tongue bud|tuberculum impar During the third week of embryological development there appears, immediately behind the ventral ends of the two halves of the mandibular arch, a rounded swelling named the tuberculum impar, which was described by His as undergoing enlargement to form the buccal part of the tongue. More recent researches, however, show that this part of the tongue is mainly, if not entirely, developed from a pair of lateral swellings which rise from the inner surface of the mandibular arch and meet in the middle line. The site of their meeting remains post-embryonically as the median sulcus of the tongue. The tuberculum impar is said to form the central part of the tongue immediately in front of the foramen cecum, but Hammar insists that it is purely a transitory structure and forms no part of the adult tongue[WP, Gray's]. CHEBI:55331 16-feruloyloxypalmitate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_55331 CHEBI:3110 biotinyl-5'-AMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_3110 CHEBI:137740 UDP-3-O-[(3R)-hydroxyacyl]-alpha-D-glucosamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137740 CHEBI:55330 16-feruloyloxypalmitic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55330 CHEBI:55333 glycosylrhamnose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55333 CHEBI:55332 beta-D-galactosyl-(1->4)-L-rhamnose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_55332 CHEBI:55328 16-hydroxyhexadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55328 CHEBI:55327 aci-nitroethane(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55327 CHEBI:31359 carminomycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31359 CHEBI:55329 16-hydroxyhexadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_55329 GO:0150057 amylin receptor complex 2 biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0150057 AMY2 complex A G protein-coupled receptor complex that serves as a receptor for amylin polypeptide (AMY) and consists of a calcitonin receptor (CTR/CALCR) and a receptor activity-modifying protein (RAMP) 2. Amylin receptor complex 2 (AMY2) also serves as a receptor for adrenomedullin (AM/ADM). GO:0150056 amylin receptor complex 1 biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0150056 AMY1 complex A G protein-coupled receptor complex that serves as a receptor for amylin polypeptide (AMY) and consists of a calcitonin receptor (CTR/CALCR) and a receptor activity-modifying protein (RAMP) 1. Amylin receptor complex 1 (AMY1) also serves as a receptor for the calcitonin related peptide (CGRP) and adrenomedullin (AM/ADM). GO:0150054 regulation of postsynaptic neurotransmitter receptor diffusion trapping biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0150054 Any process that modulates the frequency, rate or extent of postsynaptic neurotransmitter receptor diffusion trapping. GO:0150053 cerebellar climbing fiber to Purkinje cell synapse biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0150053 cerebellar climbing fibre to Purkinje cell synapse A synapse of a climbing fiber onto the dendrites of a Purkinje cell in cerebellum. The climbing fiber originates from the inferior olivary nucleus of the medulla oblongata. GO:0150052 regulation of postsynapse assembly biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0150052 Any process that modulates the frequency, rate or extent of postsynapse assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynapse. GO:0150051 postsynaptic Golgi apparatus biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0150051 Golgi outpost The network of the Golgi apparatus structures located within the postsynapse. GO:0150050 postsynaptic septin cytoskeleton biolink:CellularComponent go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0150050 The portion of the septin cytoskeleton contained within the postsynapse. GO:0150059 amylin receptor 1 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150059 AMY1 signaling pathway A series of molecular signals initiated by an extracellular amylin, or another ligand, combining with an amylin receptor 1 (AMY1), a G protein-coupled receptor complex, on the surface of the target cell. Other ligands that have been shown to initiate the AMY1 signaling pathway include the calcitonin related peptide (CGRP) and adrenomedullin (AM/ADM). GO:0150058 amylin receptor complex 3 biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0150058 AMY3 complex A G protein-coupled receptor complex that serves as a receptor for amylin polypeptide (AMY) and consists of a calcitonin receptor (CTR/CALCR) and a receptor activity-modifying protein (RAMP) 3. Amylin receptor complex 3 (AMY3) also serves as a receptor for the amyloid-beta complex. Ligand binding to AMY3 results in increased cytosolic calcium ion levels and in activation on multiple intracellular signalling pathways. CHEBI:55324 gastrointestinal drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55324 CHEBI:55323 antidiarrhoeal drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55323 CHEBI:31355 carboplatin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31355 CHEBI:55322 mu-opioid receptor agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_55322 GO:0150060 amylin receptor 2 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150060 AMY2 signaling pathway A series of molecular signals initiated by an extracellular amylin, or another ligand, combining with an amylin receptor 2 (AMY2), a G protein-coupled receptor complex, on the surface of the target cell. The AMY2 signaling pathway can also be initiated by adrenomedullin (AM/ADM). GO:0150068 positive regulation of tubulin deacetylase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150068 Any process that activates or increases the frequency, rate or extent of tubulin deacetylase activity. GO:0150067 regulation of tubulin deacetylase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150067 Any process that modulates the frequency, rate or extent of tubulin deacetylase activity. GO:0150066 negative regulation of deacetylase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150066 Any process that stops, prevents or reduces the frequency, rate or extent of deacetylase activity. CHEBI:45996 ribothymidine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_45996 GO:0150065 regulation of deacetylase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150065 Any process that modulates the frequency, rate or extent of deacetylase activity. GO:0150064 vertebrate eye-specific patterning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150064 binocular vision development|eye-specific segregation|eye-specific patterning|vertebrate eye-specific segregation Early postnatal vertebrate developmental process, during which axons of retinal ganglion cells (RGCs), transmitting overlapping inputs from both eyes, segregate into distinct eye-specific non-overlapping regions in the dorsal lateral geniculate nucleus (dLGN) of the thalamus. GO:0150063 visual system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150063 visual pathway development|optic pathway development The process whose specific outcome is the progression of the visual system over time, from its formation to the mature structure, including the eye, parts of the central nervous system (CNS) involved in processing of visual inputs, and connecting nerve pathways. GO:0150062 complement-mediated synapse pruning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150062 synapse elimination|synapse clearance|synapse disassembly|synapse removal|complement-dependent synapse pruning Synaptic pruning mediated by complement system signalling. GO:0150061 amylin receptor 3 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150061 AMY3 signaling pathway A series of molecular signals initiated by an extracellular amylin, or another ligand, combining with an amylin receptor 3 (AMY3), a G protein-coupled receptor complex, on the surface of the target cell. The AMY3 signaling pathway can also be initiated by the amyloid-beta complex. AMY3 signaling results in increased import of calcium ions into the cytosol across plasma membrane, increased phosphorylation of ERK1/2, Act, and a PKA regulatory subunit II, as well as increased expression of cFos. CHEBI:137723 16-epiestriol 16-O-(beta-D-glucuronide) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137723 CHEBI:137720 16-epiestriol 3-O-(beta-D-glucuronide) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137720 CHEBI:137724 7-oxotaurolithocholate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137724 GO:0150069 negative regulation of tubulin deacetylase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150069 Any process that stops, prevents or reduces the frequency, rate or extent of tubulin deacetylase activity. CHEBI:55310 poly(2,5-ethylene furandicarboxylate) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_55310 GO:0042480 negative regulation of eye photoreceptor cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042480 downregulation of eye photoreceptor cell development|down regulation of eye photoreceptor cell development|inhibition of eye photoreceptor cell development|negative regulation of eye photoreceptor development|down-regulation of eye photoreceptor cell development Any process that stops, prevents, or reduces the frequency, rate or extent of eye photoreceptor development. GO:0042486 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042486 GO:0042485 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042485 GO:0042488 positive regulation of odontogenesis of dentin-containing tooth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042488 up regulation of odontogenesis|positive regulation of odontogenesis of dentine-containing teeth|activation of odontogenesis|positive regulation of odontogenesis of dentine-containing tooth|stimulation of odontogenesis|up-regulation of odontogenesis|upregulation of odontogenesis Any process that activates or increases the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages that are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates. GO:0042487 regulation of odontogenesis of dentin-containing tooth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042487 regulation of odontogenesis of dentine-containing teeth|regulation of odontogenesis of dentine-containing tooth Any process that modulates the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates. GO:0042482 positive regulation of odontogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042482 stimulation of odontogenesis|up-regulation of odontogenesis|positive regulation of odontogenesis of calcareous or chitinous tooth|upregulation of odontogenesis|positive regulation of tooth development|up regulation of odontogenesis|activation of odontogenesis Any process that activates or increases the frequency, rate or extent of the formation and development of a tooth or teeth. GO:0042481 regulation of odontogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042481 regulation of tooth development|regulation of odontogenesis of calcareous or chitinous tooth Any process that modulates the frequency, rate or extent of the formation and development of a tooth or teeth. GO:0042484 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042484 GO:0042483 negative regulation of odontogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042483 down-regulation of odontogenesis|negative regulation of odontogenesis of calcareous or chitinous tooth|inhibition of odontogenesis|down regulation of odontogenesis|negative regulation of tooth development|downregulation of odontogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of a tooth or teeth. GO:0042489 negative regulation of odontogenesis of dentin-containing tooth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042489 down regulation of odontogenesis|downregulation of odontogenesis|down-regulation of odontogenesis|negative regulation of odontogenesis|negative regulation of odontogenesis of dentine-containing teeth|negative regulation of odontogenesis of dentine-containing tooth|inhibition of odontogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx. CHEBI:137373 Ni(II)-pyridinium-3,5-bisthiocarboxylate mononucleotide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137373 CHEBI:137372 pyridinium-3,5-bisthiocarboxylate mononucleotide(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137372 CHEBI:137376 long-chain fatty acyl-AMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137376 GO:0042491 inner ear auditory receptor cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042491 auditory receptor cell differentiation|auditory hair cell differentiation The process in which a relatively unspecialized inner cell acquires specialized features of an auditory hair cell. GO:0042490 mechanoreceptor differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042490 The process in which a relatively unspecialized cell acquires specialized features of a mechanoreceptor, a cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system. CHEBI:137391 18-hydroxyleukotriene B4(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137391 CHEBI:137390 19-hydroxyleukotriene B4(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137390 GO:0042497 triacyl lipopeptide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042497 triacylated lipopeptide binding|bacterial triacyl lipopeptide binding|bacterial triacyl lipoprotein binding Interacting selectively and non-covalently with a lipopeptide containing a nonprotein moiety consisting of three acyl groups. GO:0042496 detection of diacyl bacterial lipopeptide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042496 detection of diacylated bacterial lipoprotein|perception of diacylated bacterial lipoprotein|perception of diacylated bacterial lipopeptide The series of events in which a diacylated bacterial lipopeptide stimulus is received by a cell and converted into a molecular signal. Diacylated bacterial lipoproteins are lipopeptides of bacterial origin containing a nonprotein moiety consisting of two acyl groups. GO:0042499 obsolete signal peptide peptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042499 signal peptide peptidase activity|SPP OBSOLETE. Catalysis of the intramembrane proteolysis of a signal peptide, following its removal from a preprotein. GO:0042498 diacyl lipopeptide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042498 diacylated lipopeptide binding|bacterial diacyl lipoprotein binding|bacterial diacyl lipopeptide binding Interacting selectively and non-covalently with a lipopeptide containing a nonprotein moiety consisting of two acyl groups. GO:0042493 response to drug biolink:BiologicalProcess go-plus goslim_candida http://purl.obolibrary.org/obo/GO_0042493 drug susceptibility/resistance|drug resistance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease. GO:0042492 gamma-delta T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042492 gamma-delta T-lymphocyte differentiation|gamma-delta T cell development|gamma-delta T lymphocyte differentiation|gamma-delta T-cell differentiation The process in which a relatively unspecialized hemopoietic cell acquires specialized features of a gamma-delta T cell. A gamma-delta T cell is a T cell that expresses a gamma-delta T cell receptor complex. GO:0042495 detection of triacyl bacterial lipopeptide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042495 perception of triacylated bacterial lipoprotein|perception of triacylated bacterial lipopeptide|detection of triacylated bacterial lipoprotein The series of events in which a triacylated bacterial lipoprotein stimulus is received by a cell and converted into a molecular signal. Triacylated bacterial lipoproteins are lipopeptides of bacterial origin containing a nonprotein moiety consisting of three acyl groups. GO:0042494 detection of bacterial lipoprotein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042494 perception of bacterial lipoprotein|perception of Lpp|detection of Lpp|perception of BLP|detection of BLP The series of events in which a bacterial lipoprotein stimulus is received by a cell and converted into a molecular signal. Bacterial lipoproteins are lipoproteins characterized by the presence of conserved sequence motifs called pathogen-associated molecular patterns (PAMPs). CHEBI:137385 (24S)-hydroxycholesterol 24-sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137385 CHEBI:137389 (24S)-hydroxycholesterol 3,24-disulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137389 CHEBI:137388 (24S)-hydroxycholesterol 3-sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137388 CHEBI:137387 4-O-methyl-dTMP(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137387 CHEBI:137386 thymidine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137386 BSPO:0000099 posterior_to biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BSPO_0000099 BSPO:0000099 caudal_to x posterior_to y iff x is further along the antero-posterior axis than y, towards the body/tail. An antero-posterior axis is an axis that bisects an organism from head end to opposite end of body or tail. BSPO:0000098 dorsal_to biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BSPO_0000098 BSPO:0000098 x dorsal_to y iff x is further along the dorso-ventral axis than y, towards the back. A dorso-ventral axis is an axis that bisects an organism from back (e.g. spinal column) to front (e.g. belly). CHEBI:137358 1-(5-O-phosphono-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridinium-3-carbonyl adenylate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137358 CHEBI:137357 S-[1-(5-O-phosphono-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridinium-3-carbonyl]-L-cysteine(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137357 CHEBI:137351 5-hydroxymethyldeoxycytidine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137351 CHEBI:137356 S-[5-carboxy-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridinium-3-carbonyl]-L-cysteine(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137356 CHEBI:137355 5-carboxy-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridinium-3-carbonyl adenylate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137355 BSPO:0000097 distal_to biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BSPO_0000097 BSPO:0000097 x distal_to y iff x is further along the proximo-distal axis than y, towards the appendage tip. A proximo-distal axis extends from tip of an appendage (distal) to where it joins the body (proximal). CHEBI:137353 pyridinium-3,5-biscarboxylate mononucleotide(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137353 BSPO:0000096 anterior_to biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BSPO_0000096 BSPO:0000096 x anterior_to y iff x is further along the antero-posterior axis than y, towards the head. An antero-posterior axis is an axis that bisects an organism from head end to opposite end of body or tail: bearer CHEBI:137370 20-hydroxyprostaglandin E2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137370 CHEBI:137336 8-amino-8-demethylriboflavin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137336 CHEBI:137333 anaerobilin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137333 CHEBI:137340 8-demethyl-8-(methylamino)riboflavin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137340 CHEBI:137345 13-HETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137345 CHEBI:137344 7-HETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137344 CHEBI:137343 (R)-2-(phosphonomethyl)malic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137343 CHEBI:137342 13-hydroxy-14,15-epoxy-(5Z,8Z,11Z)-icosatrienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137342 CHEBI:137310 3-(methylaminomethyl)indole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137310 CHEBI:137328 epoxy(hydroxy)icosatrienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137328 CHEBI:137323 O-(alpha-D-mannosyl)-L-threonine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137323 CHEBI:137321 O-(alpha-D-mannosyl)-L-serine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137321 CHEBI:137320 (13S)-hydroxy-(14S,15S)-epoxy-(5Z,8Z,11Z)-icosatrienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137320 GO:0042400 ectoine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042400 ectoine catabolism|ectoine breakdown|ectoine degradation The chemical reactions and pathways resulting in the breakdown of ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid), a tetrahydropyrimidine commonly synthesized by halophilic bacteria. GO:0042406 extrinsic component of endoplasmic reticulum membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042406 extrinsic to ER membrane|extrinsic to endoplasmic reticulum membrane The component of the endoplasmic reticulum membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. GO:0042405 nuclear inclusion body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042405 An intranuclear focus at which aggregated proteins have been sequestered. CHEBI:45906 suramin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_45906 GO:0042408 obsolete myrcene/(E)-beta-ocimene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042408 EC:4.6.-.- myrcene/ocimene synthase activity|myrcene/(E)-beta-ocimene synthase activity OBSOLETE. Catalysis of the conversion of geranyl diphosphate (GPP) into the acyclic monoterpenes beta-myrcene, (E)-beta-ocimene, and other minor cyclic monoterpenes. GO:0042407 cristae formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042407 The assembly of cristae, the inwards folds of the inner mitochondrial membrane. GO:0042402 cellular biogenic amine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042402 biogenic amine degradation|biogenic amine catabolism|biogenic amine breakdown The chemical reactions and pathways occurring at the level of individual cells resulting in the breakdown of biogenic amines, any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters. GO:0042401 cellular biogenic amine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042401 biogenic amine synthesis|biogenic amine formation|biogenic amine biosynthesis|biogenic amine anabolism The chemical reactions and pathways occurring at the level of individual cells resulting in the formation of any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters. GO:0042404 thyroid hormone catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042404 thyroid hormone degradation|thyroid hormone breakdown|thyroid hormone catabolism The chemical reactions and pathways resulting in the breakdown of any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine. GO:0042403 thyroid hormone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042403 thyroid hormone metabolism The chemical reactions and pathways involving any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine. GO:0042409 caffeoyl-CoA O-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042409 EC:2.1.1.104|RHEA:16925|MetaCyc:CAFFEOYL-COA-O-METHYLTRANSFERASE-RXN S-adenosyl-L-methionine:caffeoyl-CoA 3-O-methyltransferase activity|trans-caffeoyl-CoA 3-O-methyltransferase activity|caffeoyl-CoA 3-O-methyltransferase activity|caffeoyl coenzyme A methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + caffeoyl-CoA = S-adenosyl-L-homocysteine + feruloyl-CoA. GO:0042411 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042411 GO:0042410 6-carboxyhexanoate-CoA ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042410 KEGG_REACTION:R03209|EC:6.2.1.14|MetaCyc:6-CARBOXYHEXANOATE--COA-LIGASE-RXN|RHEA:14781 pimeloyl-CoA synthetase activity|6-carboxyhexanoyl-CoA synthetase activity|6-carboxyhexanoate:CoA ligase (AMP-forming)|pimelyl-CoA synthetase activity Catalysis of the reaction: ATP + CoA + pimelate = AMP + diphosphate + H(+) + pimelyl-CoA. GO:0042417 dopamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042417 dopamine metabolism The chemical reactions and pathways involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline. GO:0042416 dopamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042416 dopamine anabolism|dopamine synthesis|dopamine formation|dopamine biosynthesis The chemical reactions and pathways resulting in the formation of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline. GO:0042419 epinephrine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042419 epinephrine breakdown|adrenaline catabolic process|epinephrine catabolism|adrenaline catabolism|epinephrine degradation The chemical reactions and pathways resulting in the breakdown of epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine. GO:0042418 epinephrine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042418 epinephrine anabolism|epinephrine biosynthesis|adrenaline biosynthetic process|epinephrine synthesis|adrenaline biosynthesis|epinephrine formation The chemical reactions and pathways resulting in the formation of epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine. GO:0042413 carnitine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042413 carnitine catabolism|vitamin Bt catabolism|carnitine degradation|vitamin Bt catabolic process|carnitine breakdown The chemical reactions and pathways resulting in the breakdown of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane. GO:0042412 taurine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042412 taurine biosynthesis|taurine anabolism|taurine synthesis|taurine formation The chemical reactions and pathways resulting in the formation of taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats. GO:0042415 norepinephrine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042415 noradrenaline metabolism|noradrenaline metabolic process|levarterenol metabolism|norepinephrine metabolism|levarterenol metabolic process The chemical reactions and pathways involving norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine. GO:0042414 epinephrine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042414 epinephrine metabolism|adrenaline metabolism|adrenaline metabolic process The chemical reactions and pathways involving epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine. CHEBI:79246 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79246 CHEBI:21949 O-butanoyl-L-carnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_21949 PO:0006204 sporocyte biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0006204 胞子母細胞 (Japanese, exact)|esporocito (Spanish, exact)|meiocyte (exact)|spore mother cell (exact) A native plant cell (PO:0025606) which is diploid (2n), and undergoes meiosis (GO:0007126) to produce four haploid (1n) plant spores (PO:0025017). GO:0042420 dopamine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042420 dopamine catabolism|dopamine degradation|dopamine breakdown The chemical reactions and pathways resulting in the breakdown of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline. GO:0042422 norepinephrine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042422 Wikipedia:Norepinephrine#Degradation norepinephrine catabolism|noradrenaline catabolism|levarterenol catabolic process|levarterenol catabolism|norepinephrine degradation|noradrenaline catabolic process|norepinephrine breakdown The chemical reactions and pathways resulting in the breakdown of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine. GO:0042421 norepinephrine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042421 norepinephrine biosynthesis|norepinephrine anabolism|noradrenaline biosynthesis|noradrenaline biosynthetic process|norepinephrine synthesis|norepinephrine formation|levarterenol biosynthesis|levarterenol biosynthetic process The chemical reactions and pathways resulting in the formation of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine. GO:0042428 serotonin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042428 serotonin metabolism The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. GO:0042427 serotonin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042427 Wikipedia:Serotonin serotonin biosynthesis|serotonin anabolism|serotonin synthesis|serotonin formation The chemical reactions and pathways resulting in the formation of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. GO:0042429 serotonin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042429 serotonin breakdown|serotonin catabolism|serotonin degradation The chemical reactions and pathways resulting in the breakdown of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. GO:0042424 catecholamine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042424 catecholamine breakdown|catecholamine catabolism|catecholamine degradation The chemical reactions and pathways resulting in the breakdown of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. GO:0042423 catecholamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042423 Wikipedia:Catecholamines catecholamine anabolism|catecholamine synthesis|catecholamine formation|catecholamine biosynthesis The chemical reactions and pathways resulting in the formation of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. GO:0042426 choline catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042426 choline degradation|choline breakdown|choline catabolism The chemical reactions and pathways resulting in the breakdown of choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine. GO:0042425 choline biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042425 MetaCyc:PWY-4762 choline anabolism|choline synthesis|choline formation|choline biosynthesis The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine. PO:0006210 protoderm biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0006210 protodermis (Spanish, exact)|dermatogen cell (related)|前表皮、原表皮 (Japanese, exact)|portion of protoderm tissue (exact) A portion of meristem tissue (PO:0009013) that is the outer layer of an apical meristem (PO:0020144), or the outer layer of a plant embryo proper (PO:0000001), and gives rise to a portion of epidermis (PO:0005679). CHEBI:21911 N(alpha)-methyl-L-histidines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21911 GO:0042431 indole metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042431 indole metabolism The chemical reactions and pathways involving indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan). GO:0042430 indole-containing compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042430 indole derivative metabolism|ketole metabolic process|indole-containing compound metabolism|indole and derivative metabolic process|indole derivative metabolic process|indole and derivative metabolism|ketole metabolism The chemical reactions and pathways involving compounds that contain an indole (2,3-benzopyrrole) skeleton. GO:0042433 indole catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042433 indole degradation|indole breakdown|indole catabolism The chemical reactions and pathways resulting in the breakdown of indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan). GO:0042432 indole biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042432 indole biosynthesis|indole anabolism|indole synthesis|indole formation The chemical reactions and pathways resulting in the formation of indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan). GO:0042439 ethanolamine-containing compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042439 ethanolamine and derivative metabolism|ethanolamine-containing compound metabolism|ethanolamine and derivative metabolic process The chemical reactions and pathways involving ethanolamine (2-aminoethanol) and compounds derived from it. GO:0042438 melanin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042438 melanin formation|melanin biosynthesis|melanin anabolism|melanin synthesis The chemical reactions and pathways resulting in the formation of melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom. GO:0042435 indole-containing compound biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042435 indole-containing compound biosynthesis|indole-containing compound anabolism|indole derivative biosynthesis|indole derivative biosynthetic process|indole-containing compound synthesis|indole-containing compound formation The chemical reactions and pathways resulting in the formation of compounds that contain an indole (2,3-benzopyrrole) skeleton. GO:0042434 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042434 GO:0042437 indoleacetic acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042437 indole acetic acid catabolic process|indole acetic acid catabolism|indoleacetic acid degradation|indoleacetic acid breakdown|IAA catabolic process|indoleacetic acid catabolism The chemical reactions and pathways resulting in the breakdown of indole-3-acetic acid, a compound which functions as a growth regulator in plants. GO:0042436 indole-containing compound catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042436 indole-containing compound catabolism|indole derivative catabolism|indole-containing compound degradation|indole derivative catabolic process|indole-containing compound breakdown The chemical reactions and pathways resulting in the breakdown of compounds that contain an indole (2,3-benzopyrrole) skeleton. GO:0042442 melatonin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042442 melatonin catabolism|melatonin degradation|melatonin breakdown The chemical reactions and pathways resulting in the breakdown of melatonin (N-acetyl-5-methoxytryptamine). GO:0042441 eye pigment metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042441 eye pigment metabolism The chemical reactions and pathways involving eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye. GO:0042444 phenylethylamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042444 phenylethylamine anabolism|phenylethylamine synthesis|phenylethylamine biosynthesis|phenylethylamine formation The chemical reactions and pathways resulting in the formation of phenylethylamine, an amine with pharmacological properties similar to those of amphetamine, occurs naturally as a neurotransmitter in the brain, and is present in chocolate and oil of bitter almonds. GO:0042443 phenylethylamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042443 phenylethylamine metabolism The chemical reactions and pathways involving phenylethylamine, an amine with pharmacological properties similar to those of amphetamine, occurs naturally as a neurotransmitter in the brain, and is present in chocolate and oil of bitter almonds. GO:0042440 pigment metabolic process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0042440 pigment metabolism The chemical reactions and pathways involving pigment, any general or particular coloring matter in living organisms, e.g. melanin. GO:0042449 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042449 GO:0042446 hormone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042446 hormone anabolism|hormone synthesis|hormone formation|hormone biosynthesis The chemical reactions and pathways resulting in the formation of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone. CHEBI:79276 1-hexadecyl-2-glutaryl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79276 GO:0042445 hormone metabolic process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0042445 hormone metabolism The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone. CHEBI:221278 (R)-nipecotic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_221278 GO:0042448 progesterone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042448 progesterone metabolism The chemical reactions and pathways involving progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants. CHEBI:79274 1-hexadecyl-2-succinyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79274 GO:0042447 hormone catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042447 hormone breakdown|hormone catabolism|hormone degradation The chemical reactions and pathways resulting in the breakdown of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone. CHEBI:79277 1-palmityl-2-acetyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79277 PR:000016156 telethonin biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000016156 TCAP|titin cap protein A protein that is a translation product of the human TCAP gene or a 1:1 ortholog thereof. GO:0042453 deoxyguanosine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042453 deoxyguanosine metabolism The chemical reactions and pathways involving deoxyguanosine, a nucleoside consisting of the base guanine and the sugar deoxyribose. GO:0042452 deoxyguanosine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042452 deoxyguanosine anabolism|deoxyguanosine synthesis|deoxyguanosine formation|deoxyguanosine biosynthesis The chemical reactions and pathways resulting in the formation of deoxyguanosine, a nucleoside consisting of the base guanine and the sugar deoxyribose. GO:0042455 ribonucleoside biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042455 ribonucleoside anabolism|ribonucleoside synthesis|ribonucleoside formation|ribonucleoside biosynthesis The chemical reactions and pathways resulting in the formation of any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule. GO:0042454 ribonucleoside catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042454 ribonucleoside degradation|ribonucleoside catabolism|ribonucleoside breakdown The chemical reactions and pathways resulting in the breakdown of any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule. GO:0042451 purine nucleoside biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042451 purine nucleoside formation|purine nucleoside biosynthesis|purine nucleoside anabolism|purine nucleoside synthesis The chemical reactions and pathways resulting in the formation of any purine nucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside). GO:0042450 arginine biosynthetic process via ornithine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042450 arginine anabolism via ornithine|arginine synthesis via ornithine|arginine formation via ornithine The chemical reactions and pathways resulting in the formation of arginine (2-amino-5-guanidinopentanoic acid) via the intermediate compound ornithine. CHEBI:79283 1-hexadecyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79283 CHEBI:79280 1-hexadecyl-2-acetyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79280 GO:0042457 ethylene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042457 ethylene breakdown|ethene catabolism|ethene catabolic process|ethylene catabolism|ethylene degradation The chemical reactions and pathways resulting in the breakdown of ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator. GO:0042456 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042456 GO:0042459 octopine catabolic process to proline biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042459 MetaCyc:OCTOPINEDEG-PWY octopine breakdown to proline|octopine degradation to proline The chemical reactions and pathways resulting in the breakdown of octopine into other compounds, including proline. GO:0042458 nopaline catabolic process to proline biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042458 MetaCyc:NOPALINEDEG-PWY nopaline degradation to proline|nopaline breakdown to proline The chemical reactions and pathways resulting in the breakdown of nopaline into other compounds, including proline. CHEBI:79284 trehalulose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79284 CHEBI:79289 N(5)-phenyl-L-glutamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79289 GO:0042464 dosage compensation by hypoactivation of X chromosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042464 Compensating for the two-fold variation in X:autosome chromosome ratios between sexes by an inactivation of a proportion of genes on both of the X chromosomes of the XX sex, leading to a decrease, of half, of the levels of gene expression from these chromosomes. An example of this process is found in Caenorhabditis elegans. GO:0042463 ocellus photoreceptor cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042463 non-eye photoreceptor development Development of photoreceptors, sensory cells that react to the presence of light, found in the ocellus. GO:0042466 chemokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042466 Wikipedia:Chemokinesis A response by a motile cell to a soluble chemical that involves an increase or decrease in speed (positive or negative orthokinesis) or of frequency of movement or a change in the frequency or magnitude of turning behavior (klinokinesis). GO:0042465 kinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042465 Wikipedia:Kinesis The movement of a cell or organism in response to a stimulus in which the rate of movement depends on the intensity (rather than the direction) of the stimulus. GO:0042460 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042460 GO:0042462 eye photoreceptor cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042462 Development of a photoreceptor, a sensory cell in the eye that reacts to the presence of light. They usually contain a pigment that undergoes a chemical change when light is absorbed, thus stimulating a nerve. GO:0042461 photoreceptor cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042461 photoreceptor morphogenesis Development of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. CHEBI:79293 2-hydroxy-7-methoxy-5-methyl-1-naphthoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79293 GO:0042468 klinokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042468 The movement of a cell or organism in response to a stimulus in which the frequency or magnitude of turning behavior is altered. GO:0042467 orthokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042467 The movement of a cell or organism in response to a stimulus in which the speed or frequency of movement is increased or decreased. CHEBI:79297 2-deoxy-alpha-L-fucosylaclacinomycin S biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79297 GO:0042469 versicolorin reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042469 Catalysis of the reduction of versicolorin A to sterigmatocystin. CHEBI:137396 5-carboxy-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridinium-3-carbonyl adenylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137396 CHEBI:137395 pyridinium-3,5-biscarboxylic acid mononucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137395 CHEBI:137399 Ni(II)-pyridinium-3,5-bisthiocarboxylic acid mononucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137399 CHEBI:137398 pyridinium-3,5-bisthiocarboxylic acid mononucleotide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137398 CHEBI:137397 1-(5-O-phosphono-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridinium-3-carbonyl adenylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137397 GO:0042475 odontogenesis of dentin-containing tooth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042475 odontogeny|odontogenesis of dentine-containing teeth|odontogenesis of dentine-containing tooth|odontosis|tooth development The process whose specific outcome is the progression of a dentin-containing tooth over time, from its formation to the mature structure. A dentin-containing tooth is a hard, bony organ borne on the jaw or other bone of a vertebrate, and is composed mainly of dentin, a dense calcified substance, covered by a layer of enamel. GO:0042474 middle ear morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042474 The process in which the anatomical structures of the middle ear are generated and organized. The middle ear is the air-filled cavity within the skull of vertebrates that lies between the outer ear and the inner ear. It is linked to the pharynx (and therefore to outside air) via the Eustachian tube and in mammals contains the three ear ossicles, which transmit auditory vibrations from the outer ear (via the tympanum) to the inner ear (via the oval window). GO:0042477 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042477 GO:0042476 odontogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042476 Wikipedia:Odontogenesis odontosis|tooth morphogenesis|tooth development|odontogenesis of calcareous or chitinous tooth|odontogeny The process whose specific outcome is the progression of a tooth or teeth over time, from formation to the mature structure(s). A tooth is any hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food. GO:0042471 ear morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042471 hearing organ morphogenesis The process in which the anatomical structures of the ear are generated and organized. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals. GO:0042470 melanosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042470 Wikipedia:Melanosome A tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. Melanosomes are synthesized in melanocyte cells. GO:0042473 outer ear morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042473 The process in which the anatomical structures of the outer ear are generated and organized. The outer ear is the part of the ear external to the tympanum (eardrum). It consists of a tube (the external auditory meatus) that directs sound waves on to the tympanum, and may also include the external pinna, which extends beyond the skull. GO:0042472 inner ear morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042472 The process in which the anatomical structures of the inner ear are generated and organized. The inner ear is the structure in vertebrates that contains the organs of balance and hearing. It consists of soft hollow sensory structures (the membranous labyrinth) containing fluid (endolymph) surrounded by fluid (perilymph) and encased in a bony cavity (the bony labyrinth). It consists of two chambers, the sacculus and utriculus, from which arise the cochlea and semicircular canals respectively. GO:0042479 positive regulation of eye photoreceptor cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042479 upregulation of eye photoreceptor cell development|stimulation of eye photoreceptor cell development|up-regulation of eye photoreceptor cell development|activation of eye photoreceptor cell development|positive regulation of eye photoreceptor development|up regulation of eye photoreceptor cell development Any process that activates or increases the frequency, rate or extent of eye photoreceptor development. GO:0042478 regulation of eye photoreceptor cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042478 regulation of eye photoreceptor development Any process that modulates the frequency, rate or extent of eye photoreceptor development. CHEBI:80291 aliphatic nitrile biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_80291 CHEBI:45863 paclitaxel biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_45863 CHEBI:70829 15-methylhexadecasphinganine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70829 CHEBI:70828 3-dehydro-15-methylhexadecasphinganine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70828 CHEBI:70827 isopentadecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70827 UBERON:0006440 os clitoris biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006440 clitoris bone|clitoral bone|os clitoridis|baubellum The ossified region of endochondral and membranous bone located in the clitoris of most mammals except humans; it is homologous to the penile bone (aka as baculum, penis bone or os penis) in male mammals CHEBI:70826 isopentadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70826 CHEBI:45869 estriol 3-O-(beta-D-glucuronide) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_45869 CHEBI:45868 dTDP-4-dehydro-beta-L-rhamnose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_45868 CHEBI:70820 cob(II)yrinic acid c monoamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70820 UBERON:0006444 annulus fibrosus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006444 fibrocartilaginous ring|anulus|anulus fibrosus|fibrous ring A ring of fibrous or fibrocartilaginous tissue (as of an intervertebral disk or surrounding an orifice of the heart). CHEBI:70838 isoheptadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70838 NCBITaxon:186623 Actinopteri organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_186623 UBERON:0006435 os penis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006435 penis bone|penile bone|os baculum|baculum the unique bone located in the glans penis of most mammals except humans; it is used for copulation and varies in size and shape by species CHEBI:45842 45842_TEMP_THYMIDINE-3'-PHOSPHATE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_45842 CHEBI:70848 isopentadecanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70848 CHEBI:70846 N-acyl-15-methylhexadecasphing-4-enine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70846 CHEBI:70845 N-acyl-15-methylhexadecasphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70845 CHEBI:70843 3-dehydro-15-methylhexadecasphinganine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70843 CHEBI:70859 neopentalenolactone D(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70859 CHEBI:70856 2-halobenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70856 CHEBI:70852 15-methylhexadecasphinganine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70852 CHEBI:70850 isoheptadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70850 CHEBI:45826 N-acetyl-L-threonine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_45826 CHEBI:70868 antileishmanial agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70868 CHEBI:70866 neopentalenolactone D biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70866 CHEBI:70865 3,20-dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70865 CHEBI:70864 20-methyl-21,22-didehydro-20,21-dihydrobotryococcene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70864 CHEBI:70863 3-methyl-1,2-didehydro-2,3-dihydrobotryococcene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70863 CHEBI:70862 2-halobenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70862 CHEBI:70861 3,22-dimethyl-1,2,23,24-tetradehydro-2,3,22,23-tetrahydrosqualene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70861 CHEBI:21858 hypusine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21858 CHEBI:70860 3-methyl-1,2-didehydro-2,3-dihydrosqualene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70860 CHEBI:21860 L-pyrrolysine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21860 CHEBI:79209 alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79209 CHEBI:79208 beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79208 NCBITaxon:147100 Rhabditophora organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_147100 CHEBI:45815 N-octanoylsphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_45815 CHEBI:79203 1-(1Z-octadecenyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79203 CHEBI:21865 N(6)-dimethylallyladenosine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21865 CHEBI:79202 ascaroside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79202 CHEBI:79201 hydroxy ketone ascaroside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79201 CHEBI:79200 (R)-dihydrocamalexate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79200 CHEBI:79207 1-(1Z-octadecenyl)-2-arachidonoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79207 CHEBI:79206 1-(1Z-octadecenyl)-2-oleoyl-sn-glycero-3-phosphoserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79206 CHEBI:79219 N-acetyl-beta-D-galactosaminyl-(1->4)-[alpha-N-acetylneuraminyl-(2->8)-alpha-N-acetylneuraminyl-(2->3)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79219 CHEBI:45804 beta-D-tagatofuranose 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_45804 CHEBI:79210 alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79210 CHEBI:79214 alpha-N-acetylneuraminyl-(2->8)-alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79214 CHEBI:79213 alpha-N-acetylneuraminosyl-(2->8)-alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79213 CHEBI:79211 1-(1Z-octadecenyl)-2-arachidonoyl-sn-glycero-3-phosphoserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79211 CHEBI:79218 N-acetyl-beta-D-galactosaminyl-(1->4)-[alpha-N-acetylneuraminyl-(2->3)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79218 CHEBI:21836 N(4)-glycosyl-L-asparagine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21836 CHEBI:79217 N-acetyl-beta-D-galactosaminyl-(1->4)-[alpha-N-acetylneuraminyl-(2->3)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79217 CHEBI:79216 alpha-N-acetylneuraminyl-(2->8)-alpha-N-acetylneuraminyl-(2->8)-alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79216 CHEBI:79215 alpha-N-acetylneuraminyl-(2->8)-alpha-N-acetylneuraminyl-(2->8)-alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79215 CHEBI:79221 3-sulfinopropionyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79221 CHEBI:79220 N-acetyl-beta-D-galactosaminyl-(1->4)-[alpha-N-acetylneuraminyl-(2->8)-alpha-N-acetylneuraminyl-(2->3)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79220 CHEBI:21844 N(5)-alkyl-L-glutamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21844 CHEBI:79222 3-sulfinopropionic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79222 CHEBI:137412 cholesteryl (11Z,14Z,17Z)-icosatrienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137412 CHEBI:137419 secondary ammonium ion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137419 CHEBI:137411 1-hexadecanoyl-2-[(11Z,14Z,17Z)-icosatrienoyl]-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137411 CHEBI:137410 (13R)-S-cysteinyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137410 CHEBI:137429 N-oleoyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137429 CHEBI:137409 L-sorbose 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137409 CHEBI:137404 5-hydroxybenzimidazole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137404 CHEBI:137403 1-hexanoyl-2-acyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137403 CHEBI:137408 (13R)-glycinylcystein-S-yl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137408 CHEBI:137407 (13R)-S-glutathionyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137407 CHEBI:137406 (R)-2-halocarboxylic acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137406 CHEBI:137405 (S)-2-halocarboxylic acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137405 CHEBI:45895 tert-butanol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_45895 CHEBI:70807 pentalenolactone E biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70807 CHEBI:70805 pentalenolactone D biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70805 CHEBI:70804 imidazol-5-ylacetic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70804 CHEBI:70802 CDP-3,6-dideoxy-alpha-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70802 CHEBI:70800 CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70800 CHEBI:70809 pentalenolactone F biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70809 CHEBI:70819 isovaleryl-L-carnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70819 CHEBI:70817 EC 1.2.1.12 [glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)] inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70817 CHEBI:70816 pentalenolactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70816 CHEBI:70815 N-acyl-1-O-beta-D-glucosyl-15-methylhexadecasphing-4-enine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70815 CHEBI:70813 glutamine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70813 CHEBI:79193 5-acetamidopentanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79193 CHEBI:79192 6-acetamido-2-oxohexanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79192 CHEBI:79199 13,14-dihydrolipoxin A4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79199 CHEBI:79196 3-linalylflaviolin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79196 CHEBI:137495 13(R)-HODE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137495 CHEBI:137494 13(S)-HETE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137494 CHEBI:137498 16-oxoresolvin D2(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137498 CHEBI:137497 7-oxoresolvin D2(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137497 CHEBI:137480 4-saturated-(3S)-hydroxyacyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137480 PATO:0000141 structure biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PATO_0000141 relational structural quality|conformation A morphology quality inhering in a bearer by virtue of the bearer's relative position, shape, arrangements and connectivity of an organism's various parts; the pattern underlying its form. CHEBI:137476 14,15-epoxy-20-hydroxy-(5Z,8Z,11Z)-icosatrienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137476 CHEBI:137475 11,12-epoxy-20-hydroxy-(5Z,8Z,14Z)-icosatrienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137475 CHEBI:137474 8,9-epoxy-20-hydroxy-(5Z,11Z,14Z)-icosatrienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137474 CHEBI:137491 epitestosterone 17-O-(beta-D-glucuronide) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137491 CHEBI:137490 17alpha-estradiol 17-O-(beta-D-glucuronide) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137490 CHEBI:137489 16alpha-hydroxyestrone 16-O-(beta-D-glucuronide) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137489 CHEBI:137483 2-O-(alpha-D-mannopyranosyl)-6-O-(6-acyl-alpha-D-mannopyranosyl)-1-phosphatidyl-1D-myo-inositol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137483 CHEBI:137488 16alpha-hydroxyestrone 3-O-(beta-D-glucuronide) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137488 CHEBI:137487 (2R,5S)-2,5-diammoniohexanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137487 CHEBI:137486 (R)-3,4-dihydroxy-2-oxobutanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137486 CHEBI:137485 (3R)-1,2-didehydro-3-hydroxy-16-methoxy-2,3-dihydrotabersonine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137485 CHEBI:137459 (9R,10S)-9,10-epoxy-18-hydroxyoctadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137459 CHEBI:137458 (9S,10R)-9,10-epoxy-18-hydroxyoctadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137458 CHEBI:137457 9,10-epoxy-18-hydroxyoctadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137457 CHEBI:137456 (S)-3,4-dihydroxy-2-oxobutanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137456 CHEBI:137455 (R)-2-hydroxy-3-oxo-4-(phosphonooxy)butanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137455 CHEBI:137469 12,13-epoxy-18-hydroxy-(9Z)-octadecenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137469 CHEBI:137467 9,10-epoxy-18-hydroxy-(12Z)-octadecenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137467 CHEBI:137461 (9S,10R)-epoxyoctadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137461 CHEBI:137460 (9R,10S)-9,10-epoxyoctadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137460 CHEBI:137463 2,6-O-bis(alpha-D-mannopyranosyl)-1-phosphatidyl-1D-myo-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137463 CHEBI:137449 phosphatidic acid 30:1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137449 CHEBI:70781 PPAR modulator biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70781 CHEBI:70780 1-deoxy-11-oxopentalenate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70780 GO:0042521 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042521 GO:0042520 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042520 GO:0042527 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042527 GO:0042526 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042526 GO:0042529 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042529 GO:0042528 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042528 GO:0042523 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042523 GO:0042522 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042522 CHEBI:79110 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79110 GO:0042525 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042525 GO:0042524 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042524 CHEBI:70789 pentalenolactone F(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70789 CHEBI:70788 pentalenolactone E(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70788 CHEBI:70787 pentalenolactone D(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70787 CHEBI:79113 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphoserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79113 CHEBI:70786 C30 botryococcene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70786 CHEBI:70785 CDP-3,6-dideoxy-alpha-D-glucose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70785 CHEBI:21815 N2-acyl-L-ornithine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21815 CHEBI:70784 CDP-alpha-D-abequose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70784 CHEBI:70783 CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70783 CHEBI:70782 PPARalpha agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70782 CHEBI:21816 N(2)-glutamino group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21816 CHEBI:70792 cobalt-precorrin-8(6-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70792 CHEBI:70791 cobalt-precorrin-7(7-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70791 CHEBI:70790 pentalenolactone(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70790 GO:0150200 regulation of transport across blood-brain barrier biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150200 Any process that modulates the frequency, rate or extent of transport across the blood-brain barrier. GO:0042530 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042530 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042532 down-regulation of tyrosine phosphorylation of Stat7 protein|negative regulation of tyrosine phosphorylation of Stat7 protein|down-regulation of tyrosine phosphorylation of Stat6 protein|inhibition of tyrosine phosphorylation of STAT protein|negative regulation of tyrosine phosphorylation of Stat6 protein|down-regulation of tyrosine phosphorylation of Stat5 protein|negative regulation of tyrosine phosphorylation of Stat5 protein|down-regulation of tyrosine phosphorylation of Stat4 protein|negative regulation of tyrosine phosphorylation of Stat4 protein|down-regulation of tyrosine phosphorylation of Stat3 protein|negative regulation of tyrosine phosphorylation of Stat3 protein|negative regulation of tyrosine phosphorylation of Stat2 protein|down-regulation of tyrosine phosphorylation of Stat2 protein|down-regulation of tyrosine phosphorylation of Stat1 protein|negative regulation of tyrosine phosphorylation of Stat1 protein|inhibition of tyrosine phosphorylation of Stat7 protein|inhibition of tyrosine phosphorylation of Stat6 protein|inhibition of tyrosine phosphorylation of Stat5 protein|inhibition of tyrosine phosphorylation of Stat4 protein|inhibition of tyrosine phosphorylation of Stat3 protein|inhibition of tyrosine phosphorylation of Stat2 protein|down-regulation of tyrosine phosphorylation of STAT protein|inhibition of tyrosine phosphorylation of Stat1 protein|down regulation of tyrosine phosphorylation of Stat7 protein|down regulation of tyrosine phosphorylation of Stat6 protein|down regulation of tyrosine phosphorylation of Stat5 protein|down regulation of tyrosine phosphorylation of Stat4 protein|downregulation of tyrosine phosphorylation of Stat7 protein|down regulation of tyrosine phosphorylation of Stat3 protein|down regulation of tyrosine phosphorylation of Stat2 protein|downregulation of tyrosine phosphorylation of Stat6 protein|downregulation of tyrosine phosphorylation of Stat5 protein|down regulation of tyrosine phosphorylation of Stat1 protein|downregulation of tyrosine phosphorylation of Stat4 protein|downregulation of tyrosine phosphorylation of Stat3 protein|downregulation of tyrosine phosphorylation of STAT protein|downregulation of tyrosine phosphorylation of Stat2 protein|downregulation of tyrosine phosphorylation of Stat1 protein|down regulation of tyrosine phosphorylation of STAT protein Any process that stops, prevents, or reduces the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein. GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042531 activation of tyrosine phosphorylation of Stat7 protein|positive regulation of tyrosine phosphorylation of Stat2 protein|activation of tyrosine phosphorylation of Stat6 protein|positive regulation of tyrosine phosphorylation of Stat1 protein|activation of tyrosine phosphorylation of Stat5 protein|upregulation of tyrosine phosphorylation of STAT protein|activation of tyrosine phosphorylation of Stat4 protein|stimulation of tyrosine phosphorylation of Stat7 protein|stimulation of tyrosine phosphorylation of Stat6 protein|activation of tyrosine phosphorylation of Stat3 protein|activation of tyrosine phosphorylation of Stat2 protein|stimulation of tyrosine phosphorylation of Stat5 protein|stimulation of tyrosine phosphorylation of Stat4 protein|activation of tyrosine phosphorylation of Stat1 protein|up-regulation of tyrosine phosphorylation of Stat7 protein|up-regulation of tyrosine phosphorylation of Stat6 protein|stimulation of tyrosine phosphorylation of Stat3 protein|stimulation of tyrosine phosphorylation of Stat2 protein|up-regulation of tyrosine phosphorylation of Stat5 protein|stimulation of tyrosine phosphorylation of STAT protein|stimulation of tyrosine phosphorylation of Stat1 protein|up-regulation of tyrosine phosphorylation of Stat4 protein|up-regulation of tyrosine phosphorylation of Stat3 protein|up-regulation of tyrosine phosphorylation of STAT protein|activation of tyrosine phosphorylation of STAT protein|up-regulation of tyrosine phosphorylation of Stat2 protein|up-regulation of tyrosine phosphorylation of Stat1 protein|upregulation of tyrosine phosphorylation of Stat7 protein|upregulation of tyrosine phosphorylation of Stat6 protein|upregulation of tyrosine phosphorylation of Stat5 protein|upregulation of tyrosine phosphorylation of Stat4 protein|upregulation of tyrosine phosphorylation of Stat3 protein|upregulation of tyrosine phosphorylation of Stat2 protein|upregulation of tyrosine phosphorylation of Stat1 protein|up regulation of tyrosine phosphorylation of STAT protein|up regulation of tyrosine phosphorylation of Stat7 protein|up regulation of tyrosine phosphorylation of Stat6 protein|positive regulation of tyrosine phosphorylation of Stat7 protein|up regulation of tyrosine phosphorylation of Stat5 protein|positive regulation of tyrosine phosphorylation of Stat6 protein|up regulation of tyrosine phosphorylation of Stat4 protein|positive regulation of tyrosine phosphorylation of Stat5 protein|up regulation of tyrosine phosphorylation of Stat3 protein|positive regulation of tyrosine phosphorylation of Stat4 protein|up regulation of tyrosine phosphorylation of Stat2 protein|positive regulation of tyrosine phosphorylation of Stat3 protein|up regulation of tyrosine phosphorylation of Stat1 protein Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein. GO:0042538 hyperosmotic salinity response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042538 response to hyperosmotic salt stress|salt tolerance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. GO:0042537 benzene-containing compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042537 benzene-containing compound metabolism|benzene and derivative metabolic process|benzene and derivative metabolism The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation, or any of its derivatives. GO:0042539 hypotonic salinity response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042539 response to hypotonic salt stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. GO:0042534 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042534 CHEBI:79122 2,7-dihydroxy-5-methyl-1-naphthoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79122 GO:0042533 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042533 GO:0042536 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042536 GO:0150202 negative regulation of transport across blood-brain barrier biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150202 Any process that stops, prevents or reduces the frequency, rate or extent of transport across blood-brain barrier. GO:0150201 positive regulation of transport across blood-brain barrier biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0150201 Any process that activates or increases the frequency, rate or extent of transport across blood-brain barrier. GO:0042535 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042535 PO:0006341 primary shoot system biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0006341 一次分げつ系 (Japanese, exact)|main stalk (related)|sistema axilar primario (Spanish, exact) A shoot system (PO:0009006) that develops from an embryo shoot apical meristem (PO:0006362). CHEBI:70799 CDP-alpha-D-abequose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70799 CHEBI:79125 2-hydroxy-7-methoxy-5-methyl-1-naphthoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79125 CHEBI:70798 15-methylhexadecasphing-4-enine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70798 CHEBI:70797 1-deoxy-11-oxopentalenic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70797 CHEBI:70796 1-deoxy-11beta-hydroxypentalenic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70796 CHEBI:21826 N(3')-acetylgentamycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21826 PO:0006343 axillary shoot system biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0006343 腋苗条系 (Japanese, exact)|sistema axilar del epiblasto (epiblastema) (Spanish, exact)|axillary branch (related)|Musa sucker (narrow) A shoot-borne shoot system (PO:0004545) that develops from an axillary bud (PO:0004709). CHEBI:70793 cob(II)yrinate c monoamide(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70793 GO:0042541 hemoglobin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042541 hemoglobin anabolism|hemoglobin biosynthesis|hemoglobin synthesis|hemoglobin formation|haemoglobin biosynthetic process|haemoglobin biosynthesis The chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin. GO:0042540 hemoglobin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042540 hemoglobin catabolism|hemoglobin hydrolysis|haemoglobin catabolic process|haemoglobin catabolism|hemoglobin degradation|hemoglobin breakdown|haemoglobin hydrolysis The chemical reactions and pathways resulting in the breakdown of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin; especially, the proteolytic cleavage of hemoglobin to yield free heme, peptides, and amino acids. GO:0042543 protein N-linked glycosylation via arginine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042543 RESID:AA0327 protein amino acid N-linked glycosylation via arginine The glycosylation of protein via peptidyl-arginine, omega-N-glycosyl-L-arginine. GO:0042542 response to hydrogen peroxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042542 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus. GO:0042549 photosystem II stabilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042549 The stabilization of the photosystem II protein complex, resulting from the phosphorylation of its structural protein subunits, in a cell actively involved in photosynthesis. GO:0042548 regulation of photosynthesis, light reaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042548 Any process that modulates the frequency, rate or extent of the light-dependent reaction of photosynthesis. GO:0042545 cell wall modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042545 The series of events leading to chemical and structural alterations of an existing cell wall that can result in loosening, increased extensibility or disassembly. GO:0042544 melibiose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042544 melibiose synthesis|melibiose formation|melibiose biosynthesis|melibiose anabolism The chemical reactions and pathways resulting in the formation of melibiose, the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose. GO:0042547 cell wall modification involved in multidimensional cell growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042547 cell wall modification during multidimensional cell growth|cell wall modification during cell expansion The series of events resulting in chemical or structural changes to existing cell walls and contribute to multidimensional cell growth. GO:0042546 cell wall biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042546 cell wall assembly A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall. Includes biosynthesis of constituent macromolecules, such as proteins and polysaccharides, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component. A cell wall is the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. GO:0042552 myelination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042552 Wikipedia:Myelin myelinogenesis The process in which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier. GO:0042551 neuron maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042551 A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state. GO:0042554 superoxide anion generation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042554 superoxide release The enzymatic generation of superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species, by a cell in response to environmental stress, thereby mediating the activation of various stress-inducible signaling pathways. GO:0042553 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042553 GO:0042550 photosystem I stabilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042550 The stabilization of the photosystem I protein complex, resulting from the phosphorylation of its structural protein subunits, in a cell actively involved in photosynthesis. GO:0042559 pteridine-containing compound biosynthetic process biolink:BiologicalProcess go-plus goslim_pombe http://purl.obolibrary.org/obo/GO_0042559 pteridine-containing compound biosynthesis|pteridine-containing compound anabolism|pterin biosynthesis|pterin biosynthetic process|pteridine-containing compound synthesis|pteridine-containing compound formation|pteridine and derivative biosynthesis|pteridine and derivative biosynthetic process The chemical reactions and pathways resulting in the formation of any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid. GO:0042556 eukaryotic elongation factor-2 kinase regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042556 eEF-2 kinase regulator Modulates the activity of the enzyme eukaryotic elongation factor-2 kinase. GO:0042555 MCM complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042555 mini-chromosome maintenance complex A hexameric protein complex required for the initiation and regulation of DNA replication. GO:0042558 pteridine-containing compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042558 pteridine-containing compound metabolism|pteridine and derivative metabolic process|pterin metabolic process|pterin metabolism|pteridine and derivative metabolism The chemical reactions and pathways involving any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid. GO:0042557 eukaryotic elongation factor-2 kinase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042557 eEF-2 kinase activator Binds to and increases the activity of the enzyme eukaryotic elongation factor-2 kinase. CHEBI:21806 N(2),N(5)-diacyl-L-ornithine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21806 CHEBI:21805 N(2')-acetylgentamycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21805 GO:0042563 obsolete importin alpha-subunit nuclear export complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042563 OBSOLETE. A protein complex which usually consists of three components, e.g. in Xenopus, the importin alpha-subunit/CAS/Ran, and which functions to transport the importin alpha-subunit out of the nucleus through the nuclear pore. GO:0042562 hormone binding biolink:MolecularActivity go-plus goslim_chembl|goslim_pir http://purl.obolibrary.org/obo/GO_0042562 Interacting selectively and non-covalently with any hormone, naturally occurring substances secreted by specialized cells that affect the metabolism or behavior of cells possessing functional receptors for the hormone. Hormones may be produced by the same, or different, cell as express the receptor. GO:0042565 RNA nuclear export complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042565 A complex which usually consists of three components, e.g. in Xenopus and yeast, the export receptor CRM1 (also known as exportin 1), the Ran protein and any RNA with a nuclear export sequence (NES). The complex acts to export RNA molecules with a NES from the nucleus through a nuclear pore. GO:0042564 NLS-dependent protein nuclear import complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042564 A dimer consisting of an alpha and a beta-subunit that imports proteins with an NLS into the nucleus through a nuclear pore. GO:0042561 alpha-amyrin synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042561 MetaCyc:RXN-8434 Catalysis of the reaction: (S)-2,3-epoxysqualene = alpha-amyrin. This reaction is a cyclization and rearrangement of (S)-2,3-epoxysqualene (2,3-oxidosqualene) into alpha-amyrin. GO:0042560 pteridine-containing compound catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042560 pteridine and derivative catabolism|pteridine-containing compound catabolism|pteridine-containing compound degradation|pteridine-containing compound breakdown|pterin catabolism|pterin catabolic process|pteridine and derivative catabolic process The chemical reactions and pathways resulting in the breakdown of any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid. GO:0042567 insulin-like growth factor ternary complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042567 IGF ternary complex A complex of three proteins, which in animals is approximately 150kDa and consists of the insulin-like growth factor (IGF), the insulin-like growth factor binding protein-3 (IGFBP-3), or -5 (IGFBP-5) and an acid-labile subunit (ALS). The complex plays a role in growth and development. GO:0042566 hydrogenosome biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0042566 Wikipedia:Hydrogenosome A spherical, membrane-bounded organelle found in some anaerobic protozoa, which participates in ATP and molecular hydrogen formation. GO:0042569 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042569 GO:0042568 insulin-like growth factor binary complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042568 IGF binary complex A complex of two proteins, which in animals is 50kDa and consists of the insulin-like growth factor (IGF) and one of the insulin-like growth factor binding protein-1 (IGFBP-1), -2 (IGFBP-2), -4 (IGFBP-4) and -6 (IGFBP-6). The complex plays a role in growth and development. GO:0042574 retinal metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042574 retinal metabolism|retinaldehyde metabolic process|retinaldehyde metabolism The chemical reactions and pathways involving retinal, a compound that plays an important role in the visual process in most vertebrates. In the retina, retinal combines with opsins to form visual pigments. Retinal is one of the forms of vitamin A. GO:0042573 retinoic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042573 vitamin A1 acid metabolic process|retinoic acid metabolism|vitamin A1 acid metabolism The chemical reactions and pathways involving retinoic acid, one of the three components that makes up vitamin A. GO:0042576 obsolete aspartyl aminopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042576 aspartyl aminopeptidase activity OBSOLETE. Catalysis of the release of an N-terminal aspartate or glutamate from a peptide, with a preference for aspartate. GO:0042575 DNA polymerase complex biolink:CellularComponent go-plus goslim_metagenomics|goslim_pir http://purl.obolibrary.org/obo/GO_0042575 A protein complex that possesses DNA polymerase activity and is involved in template directed synthesis of DNA. GO:0042570 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042570 GO:0042572 retinol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042572 Wikipedia:Retinol vitamin A1 metabolic process|vitamin A1 alcohol metabolism|vitamin A1 alcohol metabolic process|vitamin A1 metabolism|retinol metabolism The chemical reactions and pathways involving retinol, one of the three compounds that makes up vitamin A. GO:0042571 immunoglobulin complex, circulating biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042571 Wikipedia:Antibody antibody An immunoglobulin complex that is secreted into extracellular space and found in mucosal areas or other tissues or circulating in the blood or lymph. In its canonical form, a circulating immunoglobulin complex is composed of two identical heavy chains and two identical light chains, held together by disulfide bonds. Some forms of are polymers of the basic structure and contain additional components such as J-chain and the secretory component. GO:0042578 phosphoric ester hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042578 Catalysis of the reaction: RPO-R' + H2O = RPOOH + R'H. This reaction is the hydrolysis of any phosphoric ester bond, any ester formed from orthophosphoric acid, O=P(OH)3. GO:0042577 lipid phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042577 Catalysis of the reaction: a phospholipid + H2O = a lipid + phosphate. GO:0042579 microbody biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0042579 Wikipedia:Microbody Cytoplasmic organelles, spherical or oval in shape, that are bounded by a single membrane and contain oxidative enzymes, especially those utilizing hydrogen peroxide (H2O2). CHEBI:79169 15-hydroxypentadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79169 GO:0042585 germinal vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042585 primary oocyte nucleus The enlarged, fluid filled nucleus of a primary oocyte, the development of which is suspended in prophase I of the first meiotic division between embryohood and sexual maturity. GO:0042584 chromaffin granule membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042584 The lipid bilayer surrounding a chromaffin granule, a specialized secretory vesicle found in the cells of adrenal glands and various other organs, which is concerned with the synthesis, storage, metabolism, and secretion of epinephrine and norepinephrine. GO:0042587 glycogen granule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042587 NIF_Subcellular:sao1081228141 glycogen particle Cytoplasmic bead-like structures of animal cells, visible by electron microscope. Each granule is a functional unit with the biosynthesis and catabolism of glycogen being catalyzed by enzymes bound to the granule surface. GO:0042586 peptide deformylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042586 EC:3.5.1.88|RHEA:24420|MetaCyc:3.5.1.88-RXN polypeptide deformylase activity|formyl-L-methionyl peptide amidohydrolase activity|PDF activity Catalysis of the reaction: formyl-L-methionyl peptide + H2O = formate + methionyl peptide. GO:0042581 specific granule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042581 Wikipedia:Specific_granule secondary granule Granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase. GO:0042580 mannosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042580 A specialised tubular organelle, assembled in hexagonal bundles within an external membrane. Mannosomes are specific to molluscs and are thought to be involved in a general stress reaction. GO:0042583 chromaffin granule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042583 Specialized secretory vesicle found in the cells of adrenal glands and various other organs, which is concerned with the synthesis, storage, metabolism, and secretion of epinephrine and norepinephrine. GO:0042582 azurophil granule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042582 primary granule Primary lysosomal granule found in neutrophil granulocytes. Contains a wide range of hydrolytic enzymes and is released into the extracellular fluid. CHEBI:79173 dTDP-2-deoxy-beta-L-fucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79173 CHEBI:79172 2-hydroxy-6-(2-oxidophenyl)-6-oxo-cis,cis-hexa-2,4-dienoate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79172 CHEBI:79171 dTDP-beta-L-rhodosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79171 GO:0042589 zymogen granule membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042589 The lipid bilayer surrounding a zymogen granule. CHEBI:79176 aclacinomycin S biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79176 GO:0042588 zymogen granule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042588 A membrane-bounded, cytoplasmic secretory granule found in enzyme-secreting cells and visible by light microscopy. Contain zymogen, an inactive enzyme precursor, often of a digestive enzyme. CHEBI:79174 2,2',3-trihydroxydiphenyl ether(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79174 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042590 antigen presentation, exogenous antigen via MHC class I|cross-presentation|cross priming|cross presentation|antigen presentation, exogenous antigen via major histocompatibility complex class I|cross-priming|exogenous peptide antigen processing and presentation via MHC class I The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules. GO:0042596 fear response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042596 physiological fear response The response of an organism to a perceived external threat. GO:0042595 behavioral response to starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042595 behavioural response to starvation Any process that results in a change in the behavior of an organism as a result of deprivation of nourishment. GO:0042598 obsolete vesicular fraction biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042598 vesicular fraction OBSOLETE. Any of the small, heterogeneous, artifactual, vesicular particles that are formed when some cells are homogenized. GO:0042597 periplasmic space biolink:CellularComponent go-plus goslim_pir|goslim_metagenomics http://purl.obolibrary.org/obo/GO_0042597 periplasm The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria). GO:0042592 homeostatic process biolink:BiologicalProcess go-plus goslim_generic|goslim_chembl|goslim_mouse|goslim_agr http://purl.obolibrary.org/obo/GO_0042592 regulation of homeostatic process|activation of homeostatic process|positive regulation of homeostatic process|homeostasis|negative regulation of homeostatic process|inhibition of homeostatic process Any biological process involved in the maintenance of an internal steady state. CHEBI:79191 L-Cys(IAN) zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79191 GO:0042591 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042591 GO:0042594 response to starvation biolink:BiologicalProcess go-plus goslim_yeast http://purl.obolibrary.org/obo/GO_0042594 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment. GO:0042593 glucose homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042593 Any process involved in the maintenance of an internal steady state of glucose within an organism or cell. CHEBI:79183 5,10-dihydro-9-dimethylallylphenazine-1-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79183 CHEBI:79182 18-hydroxyoctadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79182 CHEBI:79181 5,10-dihydrophenazine-1-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79181 CHEBI:79188 (3R)-3-ammonio-3-phenylpropanoyl-CoA(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79188 GO:0042599 lamellar body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0042599 NIF_Subcellular:sao1379604862 membrane-coating granule|keratinosome|lamellar granule|Odland body A membrane-bounded organelle, specialized for the storage and secretion of various substances (surfactant phospholipids, glycoproteins and acid phosphates) which are arranged in the form of tightly packed, concentric, membrane sheets or lamellae. Has some similar properties to, but is distinct from, a lysosome. CHEBI:79187 pppGp(2'->5')A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79187 CHEBI:79186 3'-N-debenzoyl-2'-deoxytaxol(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_79186 CHEBI:79185 4-O-dimethylallyl-L-tyrosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79185 PR:000016261 serotransferrin biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000016261 transferrin|Trf|beta-1 metal-binding globulin|siderophilin|TF A protein that is a translation product of the human TF gene or a 1:1 ortholog thereof. CHEBI:79189 D-ribofuranose-2,5-bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79189 CHEBI:45744 N-acetyl-beta-neuraminic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_45744 CHEBI:70709 progesterone receptor agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70709 UBERON:0006563 tunica media of pulmonary trunk biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006563 Tunica media of artery which is continuous with the myocardium of right ventricle.[FMA] UBERON:0006562 pharynx biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006562 pharyngeal tube|anterior part of foregut The pharynx is the part of the digestive system immediately posterior to the mouth[GO]. UBERON:0006561 non-lymphatic part of lymphoid system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006561 non-lymphatic lymphoid system An organ system subdivision that is the part of the lymphoid system that excludes the lymphatic vessels.. UBERON:0006569 diencephalic nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006569 A nucleus of brain that is part of a diencephalon. UBERON:0006568 hypothalamic nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006568 nucleus of hypothalamus A nucleus of brain that is part of a hypothalamus. UBERON:0006567 right ventricle myocardium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006567 myocardium of right ventricle|right ventricular myocardium A myocardium that is part of a right ventricle of a heart. UBERON:0006566 left ventricle myocardium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006566 myocardium of left ventricle|left ventricular myocardium A myocardium that is part of a left ventricle of a heart. UBERON:0006565 female urethral meatus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006565 urethral meatus of clitoral urethra|distal urethral opening of female|external orifice of female urethra|female urethral meatus|external urethral orifice (female)|ostium urethrae externum (urethra feminina)|urethral opening of clitoral urethra A urethral meatus that is part of a female urethra[Automatically generated definition]. CHEBI:31107 3-amino-4,7-dihydroxycoumarin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31107 CHEBI:21787 N-seryl-glycosylphosphatidylinositolethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21787 UBERON:0006553 renal duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006553 A tube in the kidney that collect and transport urine. CHEBI:70716 cis-tetradec-5-enoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70716 CHEBI:70712 (5Z)-tetradecenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70712 CHEBI:31104 3,5-dihydroxyphenylglyoxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31104 CHEBI:31103 3,5-dihydroxyphenylacetyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31103 UBERON:0006558 lymphatic part of lymphoid system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006558 lymphatic system|lymporeticular system|lymphatic tree system An organ system subdivision that is a network of vessels capable of removing accumulating protein and fluid from the interstitial space and returning it to the vascular space. In some species, this network is connected to the immune system via lymph nodes and lymphocyte-producing organs, with the whole being the lymphoid system. UBERON:0006555 excretory tube biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006555 A tube that is part of a excretory system. CHEBI:21752 N-methyl-L-alpha-amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21752 UBERON:0006542 outer medulla outer stripe loop of Henle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006542 A loop of Henle that is part of a kidney outer medulla outer stripe. UBERON:0006541 outer medulla inner stripe loop of Henle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006541 A loop of Henle that is part of a kidney outer medulla inner stripe. CHEBI:70728 actin polymerisation inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70728 CHEBI:70727 topoisomerase inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70727 CHEBI:70726 hesperadin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70726 CHEBI:45725 spermine(4+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_45725 CHEBI:70725 adenosine A3 receptor antagonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70725 CHEBI:70724 cell dedifferentiation agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70724 CHEBI:70723 reversine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70723 CHEBI:70722 EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70722 UBERON:0006544 kidney vasculature biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006544 A vasculature that is part of a kidney. CHEBI:21760 N-methyl-amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21760 CHEBI:21763 N-methylethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21763 UBERON:0006531 oculomotor muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006531 The muscles that move the eye. Included in this group are the medial rectus, lateral rectus, superior rectus, inferior rectus, inferior oblique, superior oblique, musculus orbitalis, and levator palpebrae superioris. UBERON:0006530 seminal fluid biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006530 seminal fluid|male genital secretion|male genital fluid|seminal plasma A substance formed from the secretion of one or more glands of the male genital tract in which sperm cells are suspended. CHEBI:45718 3,3,3-tetramine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_45718 CHEBI:70738 UDP-N-acetyl-alpha-D-mannosaminouronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70738 CHEBI:45713 trans-resveratrol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_45713 UBERON:0006539 mammary gland fluid/secretion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006539 lactiferous gland fluid|mammary gland secreted fluid|mammary gland fluid|lactiferous gland secretion|secretion of mammary gland|mammary gland secretion A substance that is secreted by a mammary gland. The substance may differ depending on phase, with colostrum produced during pregancy/early lactation, and milk produced afterwards. UBERON:0006538 respiratory system fluid/secretion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006538 respiratory system secretion|respiratory system fluid A portion of organism substance that secreted_by a respiratory system. CHEBI:21766 N-methylglycines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21766 UBERON:0006537 female reproductive gland secretion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006537 female reproductive system secretion|female reproductive system fluid/secretion|female reproductive system fluid A portion of organism substance that is secreted by a female reproductive gland. UBERON:0006536 male reproductive gland secretion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006536 male reproductive system fluid/secretion|male reproductive system secretion|male reproductive system fluid A portion of organism substance that is secreted by a male reproductive gland. CHEBI:70731 UDP-N-acetyl-alpha-D-mannosaminouronate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70731 UBERON:0006535 skin secretion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006535 skin fluid/secretion|skin substance|skin fluid A portion of organism substance that secreted_by a zone of skin. UBERON:0006534 renal convoluted tubule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006534 convoluted tubule|kidney convoluted tubule Any region of a nephron tubule that is convoluted. Examples: distal convoluted tubule, proximal convoluted tuble. UBERON:0006533 rectus extraocular muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006533 UBERON:0006532 oblique extraocular muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006532 CHEBI:21732 N-glycyl-glycosylphosphatidylinositolethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21732 CHEBI:21731 N-glycosyl compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21731 CHEBI:70749 O-hexanoylcarnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70749 CHEBI:70744 Gly-Pro biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70744 UBERON:0006596 presumptive blood biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006596 future blood UBERON:0006595 presumptive endoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006595 Presumptive structure of the blastula that will develop into endoderm. CHEBI:70758 UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alaninate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70758 CHEBI:70757 UDP-N-acetyl-alpha-D-muramate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70757 CHEBI:21745 N-(long-chain-fatty-acyl)-L-glutamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21745 CHEBI:70755 methyltelluronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70755 UBERON:0006599 presumptive hypochord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006599 future hypochord Tissue is fated to develop into the hypochord. UBERON:0006598 presumptive structure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006598 future structure|presumptive structures Portion of embryonic tissue determined by fate mapping to become a structure. GO:0042505 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042505 UBERON:0006585 vestibular organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006585 balance organ An organ that is part of a vestibular system. GO:0042504 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042504 GO:0042507 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042507 GO:0042506 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042506 GO:0042501 serine phosphorylation of STAT protein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042501 serine phosphorylation of STAT3 protein The process of introducing a phosphate group to a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein. GO:0042500 aspartic endopeptidase activity, intramembrane cleaving biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0042500 Reactome:R-HSA-8863101|EC:3.4.23.- Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain, occurring within a membrane. GO:0042503 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042503 CHEBI:70768 UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70768 GO:0042502 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042502 CHEBI:70765 UDP-N-acetyl-alpha-D-muramic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70765 CHEBI:70764 tritrans,heptacis-undecaprenyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70764 CHEBI:70763 tritrans,heptacis-undecaprenyl phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70763 GO:0042509 regulation of tyrosine phosphorylation of STAT protein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0042509 regulation of tyrosine phosphorylation of Stat7 protein|regulation of tyrosine phosphorylation of Stat6 protein|regulation of tyrosine phosphorylation of Stat5 protein|regulation of tyrosine phosphorylation of Stat4 protein|regulation of tyrosine phosphorylation of Stat3 protein|regulation of tyrosine phosphorylation of Stat2 protein|regulation of tyrosine phosphorylation of Stat1 protein Any process that modulates the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein. GO:0042508 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042508 CHEBI:70760 all-trans-retinyl oleate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70760 CHEBI:70770 Aurora kinase inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70770 CHEBI:79109 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79109 GO:0042510 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042510 GO:0042516 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042516 UBERON:0006574 pectinate line biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006574 linea pectinata canalis analis|pectinate line of anal canal|site of anal membrane|dentate line|Hilton's 'white line'|linea anocutanea|recto-anal junction The pectinate line (anocutaneous line, dentate line, anorectal junction) is a line which divides the upper 2/3rds and lower 1/3rd of the anal canal. Developmentally, this line represents the hindgut-proctodeum junction. It is an important anatomical landmark, and several distinctions can be made based upon the location of a structure relative to this line: GO:0042515 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042515 GO:0042518 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042518 GO:0042517 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042517 UBERON:0006571 trabecula carnea of left ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006571 trabeculae carneae (ventriculus sinister) A trabecula carnea that is part of a heart left ventricle. GO:0042512 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042512 GO:0042511 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042511 UBERON:0006570 trabecula carnea of right ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006570 trabeculae carneae (ventriculus dexter) A trabecula carnea that is part of a heart right ventricle. GO:0042514 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042514 CHEBI:70779 1-deoxy-11beta-hydroxypentalenate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70779 GO:0042513 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042513 CHEBI:70778 GW 7647 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70778 CHEBI:79103 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79103 CHEBI:70776 N-acyl-4-hydroxy-15-methylhexadecasphinganine-1-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70776 CHEBI:79102 1-(1Z-octadecenyl)-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_79102 CHEBI:70775 N-acyl-15-methylhexadecasphing-4-enine-1-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70775 CHEBI:70774 capsaicin receptor antagonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70774 GO:0042519 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0042519 CHEBI:70773 capsazepine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70773 CHEBI:70771 15-methylhexadecasphing-4-enine(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_70771 OBA:0000011 actin filament length biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000011 length of actin filament The length of a actin filament. CHEBI:137536 (+)-corvol ether B biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137536 CHEBI:137535 (+)-corvol ether A biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137535 CHEBI:137534 3-oxocholoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137534 CHEBI:137533 (-)-alpha-amorphene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137533 CHEBI:137539 3-oxocholan-24-oyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137539 CHEBI:137537 3-oxodeoxycholoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137537 OBA:0000016 angiotensin levels in blood biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000016 blood angiotensin II amount The amount of a angiotensin II when measured in blood. CHEBI:31178 aklanonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31178 OBA:0000018 appetite biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000018 quality of hunger motivation behavior The quality of a hunger motivation behavior. CHEBI:137532 3-oxochenodeoxycholoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137532 CHEBI:137531 (3S)-(+)-asterisca-2(9),6-diene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137531 OBA:0000015 anatomical structure size biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000015 size of anatomical structure The size of a anatomical structure. CHEBI:137530 (2S,3R,6S,9S)-(-)-protoillud-7-ene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137530 CHEBI:137547 (5S,6R)-dihydroxy-(15S)-hydroperoxy-(7E,9E,11Z,13E)-icosatetraenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137547 CHEBI:137546 (5S)-hydroxy-(15S)-hydroperoxy-(6E,8Z,11Z,13E)-icosatetraenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137546 CHEBI:137545 pivaloyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137545 CHEBI:31181 aklavinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_31181 CHEBI:137544 bis(hydroperoxy)icosatetraenoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137544 OBA:0000009 RNA stability biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000009 macromolecular stability of RNA The macromolecular stability of a RNA. CHEBI:137548 hydroperoxy(hydroxy)icosatetraenoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137548 OBA:0000006 Malpighian tubule diameter biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000006 diameter of Malpighian tubule The diameter of a Malpighian tubule. OBA:0000007 Malpighian tubule size biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000007 size of Malpighian tubule The size of a Malpighian tubule. CHEBI:137543 (5S,15S)-dihydroperoxy-(6E,8Z,11Z,13E)-icosatetraenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137543 CHEBI:137542 (5S,6R)-dihydroxy-(7E,9E,11Z,14Z)-icosatetraenoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137542 OBA:0000001 biological attribute biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000001 CHEBI:31186 alfacalcidol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_31186 CHEBI:137541 N-propanoyl-L-methionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137541 CHEBI:137540 N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl-L-threonine residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137540 CHEBI:137514 TRPA1 channel agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137514 CHEBI:31157 (+)-abscisic aldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_31157 CHEBI:45791 triethylammonium ion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_45791 CHEBI:137525 CDP-D-ribose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137525 CHEBI:137524 CDP-D-ribulose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137524 CHEBI:137523 (-)-spiroviolene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137523 CHEBI:137522 (+)-isoafricanol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137522 CHEBI:137529 20-hydroxyprostaglandin A1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137529 CHEBI:137528 tsukubadiene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_137528 CHEBI:137526 20-hydroxyprostaglandin E1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137526 OBA:0000052 cell shape biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000052 shape of cell The shape of a cell. OBA:0000055 cell size biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000055 size of cell The size of a cell. OBA:0000051 cell projection size biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000051 size of cell projection The size of a cell projection. OBA:0000050 cell pH biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000050 pH of cell The pH of a cell. UBERON:0006518 right lung lobe biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006518 lobe of right lung|lobe of the right lung A lobe of lung that is part of a right lung. UBERON:0006526 right lung alveolar system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006526 UBERON:0006525 left lung alveolar system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006525 UBERON:0006524 alveolar system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006524 bronchoalveolar system|pulmonary alveolar system System pertaining to a bronchus and alveoli. OBA:0000057 cellular component size biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000057 size of cellular_component The size of a cellular_component. OBA:0000056 cell volume biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000056 volume of cell The volume of a cell. CHEBI:31132 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31132 OBA:0000058 cellular pH biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000058 The acidity when measured in cell. BSPO:0000121 in_right_side_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BSPO_0000121 BSPO:0000121 X in_right_side_of Y <=> if Y is subdivided into left and right portions, X is part_of the right portion. BSPO:0000120 in_left_side_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BSPO_0000120 BSPO:0000120 X in_left_side_of Y <=> if Y is subdivided into left and right portions, X is part_of the left portion. BSPO:0000123 in_anterior_side_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BSPO_0000123 BSPO:0000123 X anterior_side_of Y <=> if Y is subdivided into two anterior and posterior portions, X is part_of the anterior portion. BSPO:0000122 in_posterior_side_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BSPO_0000122 BSPO:0000122 X posterior_side_of Y <=> if Y is subdivided into two anterior and posterior portions, X is part_of the posterior portion. BSPO:0000125 in_distal_side_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BSPO_0000125 BSPO:0000125 X distal_side_of Y <=> if Y is subdivided into distal and proximal portions, X is part_of the distal portion. BSPO:0000124 in_proximal_side_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BSPO_0000124 BSPO:0000124 X proximal_side_of Y <=> if Y is subdivided into distal and proximal portions, X is part_of the proximal portion. OBA:0000040 calcium ion concentration biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000040 concentration of of calcium ion The concentration of of a calcium ion. BSPO:0000126 in_lateral_side_of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BSPO_0000126 BSPO:0000126 X in_lateral_side_of Y <=> if X is in_left_side_of Y or X is in_right_side_of Y. X is often, but not always a paired structure PATO:0000051 morphology biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PATO_0000051 A quality of a single physical entity inhering in the bearer by virtue of the bearer's size or shape or structure. CHEBI:137502 (S)-2,4-dihydroxy-3-oxobutanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_137502 PATO:0000052 shape biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PATO_0000052 relational shape quality A morphological quality inhering in a bearer by virtue of the bearer's ratios of distances between its features (points, edges, surfaces and also holes etc). UBERON:0006514 pallidum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0006514 neuraxis pallidum|pallidum of neuraxis Part of what are called the basal ganglia of the brain which consist of the globus pallidus and the ventral pallidum. OBA:0000046 cardiac muscle cell membrane potential biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000046 membrane potential of cardiac muscle cell The membrane potential of a cardiac muscle cell. CHEBI:31144 8-demethyltetracenomycin C biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_31144 OBA:0000048 cell diameter biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000048 diameter of cell The diameter of a cell. CHEBI:21794 N-sulfoglucosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21794 OBA:0000032 blood vessel size biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000032 size of blood vessel The size of a blood vessel. CHEBI:31116 3-hexaprenyl-4-hydroxybenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31116 CHEBI:45764 L-methionine (R)-S-oxide residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_45764 OBA:0000039 buoyancy biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000039 CHEBI:31113 3-dimethylallyl-4-hydroxyphenylpyruvic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31113 CHEBI:31112 3-dimethylallyl-4-hydroxymandelic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31112 CHEBI:31111 3-dimethylallyl-4-hydroxybenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31111 OBA:0000037 brood size biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000037 OBA:0000036 body fluid levels biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000036 The volume when measured in multicellular organism. OBA:0000022 autophagic vacuole size biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000022 size of autophagosome The size of a autophagosome. BSPO:0000100 proximal_to biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BSPO_0000100 BSPO:0000100 x proximal_to y iff x is closer to the point of attachment with the body than y. BSPO:0000102 ventral_to biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BSPO_0000102 BSPO:0000102 x ventral_to y iff x is further along the dorso-ventral axis than y, towards the front. A dorso-ventral axis is an axis that bisects an organism from back (e.g. spinal column) to front (e.g. belly). CHEBI:31128 4-hydroxyphenyl acetate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_31128 BSPO:0000107 deep_to biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BSPO_0000107 BSPO:0000107 Further away from the surface of the organism. Thus, the muscular layer is deep to the skin, but superficial to the intestines. BSPO:0000108 superficial_to biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/BSPO_0000108 BSPO:0000108 Near the outer surface of the organism. Thus, skin is superficial to the muscle layer. CHEBI:45757 (5S)-5-(carboxymethyl)-L-proline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_45757 CHEBI:31121 4'''-demalonylsalvianin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_31121 OBA:0000023 axon diameter biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/OBA_0000023 diameter of axon The diameter of a axon. UBERON:0002639 midbrain reticular formation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002639 tegmental reticular formation|formatio reticularis mesencephali|substantia reticularis mesencephali|formatio reticularis tegmenti mesencephali|formatio reticularis tegmentalis|reticular formation of midbrain|MBRF Part of the reticular formation located in the midbrain tegmentum CHEBI:84429 1-heptadecanoyl-2-stearoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84429 CHEBI:84428 1-heptadecanoyl-2-myristoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84428 CHEBI:84427 1-heptadecanoyl-2-lauroyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84427 CHEBI:84426 FAHFA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84426 CHEBI:60461 ditrans,polycis-dodecaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60461 CHEBI:84425 9-PAHSA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84425 CHEBI:84424 ubiquinol-9 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84424 CHEBI:60460 ditrans,polycis-tridecaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60460 CHEBI:60463 4-amino-4-deoxy-alpha-L-arabinopyranosyl ditrans,polycis-undecaprenyl phosphate zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60463 CHEBI:84423 3-demethylubiquinol-9 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84423 CHEBI:84422 3-demethylubiquinol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84422 CHEBI:60462 ditrans,polycis-tetradecaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60462 CHEBI:35498 diuretic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35498 PO:0006070 mesophyll biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0006070 葉肉 (Japanese, exact)|mesófilo (Spanish, exact) The chloroplast-containing, photosynthetic parenchymatous tissue situated between the two epidermal layers of the leaf or leaf like organs. CHEBI:60465 alpha-L-galactose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60465 CHEBI:60464 tri-trans,poly-cis-undecaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60464 CHEBI:35497 androgen antagonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35497 CHEBI:60467 D-alanyl-D-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60467 CHEBI:35499 hallucinogen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35499 CHEBI:60466 peptide zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60466 CHEBI:60468 ditrans,polycis-undecaprenyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60468 CHEBI:35490 trypanothione disulfide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35490 UBERON:0002642 cuneate fasciculus of medulla biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002642 fasciculus cuneatus (myelencephali)|nucleus pulvinaris oromedialis (Hassler) Part of cuneate fasciculus found in the medulla CHEBI:35492 cystine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35492 CHEBI:35491 L-cystine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35491 CHEBI:35494 D-cystine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35494 CHEBI:35493 antipyretic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35493 CHEBI:35496 fluorobenzenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35496 PO:0006079 shoot system meristem biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0006079 シュート分裂組織 (Japanese, exact)|meristema del epiblasto (epiblastema) (Spanish, exact) A portion of meristem tissue (PO:0009013) that is part of a shoot system (PO:0009006). CHEBI:59466 phosphatidylinositol mannoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59466 CHEBI:60472 4-amino-4-deoxy-alpha-L-arabinopyranosyl ditrans,polycis-undecaprenyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60472 CHEBI:60471 dUDP(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60471 CHEBI:60473 5,10-methylenetetrahydrofolate polyglutamate macromolecule biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60473 CHEBI:84432 ubiquinol-7 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84432 CHEBI:84431 3-demethylubiquinol-7 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84431 CHEBI:84430 1-heptadecanoyl-2-palmitoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84430 PO:0006063 plant ovary epidermis biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0006063 epidermis del ovario (Spanish, exact)|子房表皮 (Japanese, exact)|Poaceae ovary epidermis (narrow) A portion of epidermis (PO:0005679) that is part of an plant ovary wall (PO:0005022). CHEBI:60479 lysophosphatidylcholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60479 PO:0006060 filament epidermis biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0006060 花糸表皮 (Japanese, exact)|epidermis del filamento (Spanish, exact) A portion of stamen epidermis that is part of a filament. UBERON:0002633 motor nucleus of trigeminal nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002633 motor trigeminal nucleus|trigeminal V motor nucleus|motor nucleus of the trigeminal|motor nucleus of trigeminal nerve|nucleus motorius nervi trigemini|nucleus motorius nervi trigeminalis|trigeminal motor nuclei|nucleus motorius nervi trigemini|nV|motor nucleus of cranial nerve v|motor nucleus|motor nucleus of trigeminal|motor nucleus V|trigeminal motor nucleus|nucleus motorius trigeminalis|motor nucleus of the trigeminal nerve Nucleus located in the pontine tegmentum containing cells that give rise to motor innervation of the jaw through the trigeminal nerve. It receives both crossed and uncrossed fibers from the cerebral cortex (Heimer, L. The Human Brain and Spinal Cord, 2nd ed., 1996, pg 248). CHEBI:59458 N-[(R)-4-phosphonatopantothenoyl]-L-cysteinate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59458 CHEBI:59457 1-(5-phosphonato-beta-D-ribosyl)-5'-AMP(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59457 UBERON:0002618 root of trochlear nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002618 trochlear nerve root|fibrae nervi trochlearis|central part of trochlear nerve|trochlear nerve/root|4nf|trochlear nerve tract|trochlear nerve fibers|trochlear nerve or its root CHEBI:490095 esculetin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_490095 UBERON:0002613 cerebellum globose nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002613 posterior interpositus nucleus|medial interpositus (globose) nucleus|nucleus globosus cerebelli|nucleus interpositus posterior|medial interpositus nucleus|posterior interposed nucleus|medial interposed nucleus|nucleus globosus|globose nucleus|nuclei globosi|nucleus interpositus posterior cerebelli The two or three small masses of gray matter that is located medial to the emboliform nucleus and lateral to the fastigial nucleus; it receives axons from the intermediate area of the cerebellar hemispheres and its afferents exit through the superior cerebellar peduncle. UBERON:0002616 regional part of brain biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002616 anatomical structure of brain|neuroanatomical region|neuraxis segment|brain anatomical structure|brain biological structure|brain part|segment of brain|biological structure of brain Anatomical divisons of the brain according to one or more criteria, e.g. cytoarchitectural, gross anatomy. Parts may be contiguous in 3D or not, e.g., basal ganglia. UBERON:0002615 ventral tegmental decussation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002615 decussatio tegmenti ventralis|decussatio ventralis tegmenti|decussatio inferior (Forel)|inferior decussation (Forel's decussation)|ventral tegmental decussation (Forel)|decussation of forel|VTGX|decussatio tegmentalis anterior|ventral tegmental decussation of forel|anterior tegmental decussation CHEBI:60481 N',N'',N'''-triacetylfusarinine C biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60481 CHEBI:84447 (5Z,8Z,10E,14Z)-12-hydroxyicosatetraenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84447 CHEBI:84446 3,4-dihydroxy-5-all-trans-heptaprenylbenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84446 CHEBI:84445 N-acylheptadecasphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84445 CHEBI:84443 3-methoxy-4-hydroxy-5-all-trans-polyprenylbenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84443 CHEBI:60487 adenosylcobinamide guanosyl diphosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60487 CHEBI:35476 antipsychotic agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35476 CHEBI:35475 non-steroidal anti-inflammatory drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35475 CHEBI:84442 3-methoxy-4-hydroxy-5-all-trans-polyprenylbenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84442 CHEBI:60486 trehalose monomycolate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60486 CHEBI:60489 magnesium 13(1)-hydroxyprotoporphyrin 13-monomethyl ester(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60489 CHEBI:60488 cob(I)alamin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60488 CHEBI:35479 alkali metal salt biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35479 UBERON:0002623 cerebral peduncle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002623 cerebral peduncle|CP|cerebal peduncle|pedunculi cerebri|pedunculus cerebri|pedunculus cerebri|cerebral peduncle (archaic)|peduncle of midbrain|tegmentum|pedunculus cerebralis Synonym for macrodissected adult human tegmentum (Vicq d'Azyr, 1784; Swanson, 2000); pp. 555-556. Later used thus by for example His (1893b, p. 178), Herrick (1915, p. 160), Strong & Elwyn (1943, p. 17), Carpenter (1976, p. 367), Williams & Warwick (1980, p. 935). CHEBI:35470 central nervous system drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35470 CHEBI:35472 anti-inflammatory drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35472 CHEBI:35471 psychotropic drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35471 CHEBI:35474 anxiolytic drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35474 CHEBI:35473 tranquilizing drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35473 PO:0006039 shoot-borne root epidermis biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0006039 crown root epidermis (related)|不定根表皮 (Japanese, exact)|adventitious root epidermis (broad)|epidermis de la raíz adventicia (Spanish, exact) A portion of root epidermis (PO:0006036) that is part of a shoot-borne root (PO:0000042). UBERON:0002602 emboliform nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002602 cerebellar emboliform nucleus|anterior interpositus nucleus|nucleus emboliformis cerebelli|cerebellum emboliform nucleus|lateral interpositus nucleus|nucleus interpositus anterior cerebelli|embolus|lateral interpositus (emboliform) nucleus|anterior interposed nucleus|nucleus interpositus anterior|nucleus emboliformis the small wedge shaped nucleus interposed between the dentate and fastigial nuclei; it receives axons from Purkinje cells of the intermediate area of the cerebral hemispheres and most of its efferent connections travel via the superior cerebellar peduncle CHEBI:60490 magnesium 13(1)-oxoprotoporphyrin 13-monomethyl ester(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60490 CHEBI:60492 magnesium protoporphyrin(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60492 CHEBI:60491 magnesium protoporphyrin 13-monomethyl ester(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60491 CHEBI:60494 5-hydroxybenzimidazolylcob(I)amide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60494 CHEBI:60493 adenosylcobalamin 5'-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60493 CHEBI:84456 3-methoxy-4-hydroxy-5-all-trans-octaprenylbenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84456 CHEBI:84455 3-methoxy-4-hydroxy-5-all-trans-octaprenylbenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84455 CHEBI:35487 EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35487 CHEBI:84454 3-methoxy-4-hydroxy-5-all-trans-heptaprenylbenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84454 CHEBI:35486 maleate ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35486 CHEBI:84453 3-methoxy-4-hydroxy-5-all-trans-heptaprenylbenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84453 CHEBI:84452 3,4-dihydroxy-5-all-trans-octaprenylbenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84452 CHEBI:35489 organic disulfide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35489 CHEBI:35488 central nervous system depressant biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35488 CHEBI:84451 3,4-dihydroxy-5-all-trans-octaprenylbenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84451 CHEBI:84450 3,4-dihydroxy-5-all-trans-heptaprenylbenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84450 PO:0006041 petal epidermis biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0006041 花弁表皮 (Japanese, exact)|epidermis del pétalo (Spanish, exact) A portion of phyllome epidermis (PO:0025157) that is part of a petal (PO:0009032). PO:0006040 sepal epidermis biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0006040 epidermis del sépalo (Spanish, exact)|がく片表皮 (Japanese, exact) A portion of phyllome epidermis (PO:0025157) that is part of a sepal (PO:0009031). UBERON:0002610 cochlear nuclear complex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002610 nuclei cochleares|cochlear nuclei The cochlear nuclei consist of: (a) the dorsal cochlear nucleus, corresponding to the tuberculum acusticum on the dorso-lateral surface of the inferior peduncle; and (b) the ventral or accessory cochlear nucleus, placed between the two divisions of the nerve, on the ventral aspect of the inferior peduncle. [WP,unvetted]. PO:0006043 integument epidermis biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0006043 epidermis del integumento (Spanish, exact)|Poaceae integument epidermis (narrow)|珠皮表皮 (Japanese, exact) A portion of epidermis (PO:0005679) that is part of an integument (PO:0020021). CHEBI:35481 non-narcotic analgesic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35481 CHEBI:35480 analgesic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35480 CHEBI:59436 L-lactyl-2-diphospho-5'-guanosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59436 PO:0006048 seed coat epidermis biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0006048 種子種皮表皮 (Japanese, exact)|epidermis de la cubierta de la semilla (Spanish, exact) A portion of epidermis (PO:0005679) that is part of a seed coat (PO:0009088). CHEBI:59435 L-lactyl-2-diphospho-5'-guanosine(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59435 CHEBI:35482 opioid analgesic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35482 CHEBI:35484 phthalate ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35484 CHEBI:59433 2-phospho-L-lactate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59433 CHEBI:84468 12-PAHSA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84468 CHEBI:84467 1-stearoyl-sn-glycero-3-phosphoserine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84467 CHEBI:84466 1-stearoyl-2-linoleoyl-sn-glycero-3-phospho-L-serine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84466 CHEBI:84465 acyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84465 CHEBI:35453 5-dehydro-4-deoxy-D-glucarate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35453 CHEBI:84462 1-heptadecanoyl-sn-glycero-3-phosphoserine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84462 CHEBI:84461 1-heptadecanoyl-2-arachidonoyl-sn-glycero-3-phosphoserine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84461 CHEBI:35457 EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35457 GO:0061801 laminin-5B complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061801 laminin 3B32 complex A laminin complex composed of alpha3B, beta3 and gamma2 polypeptide chains. GO:0061800 fibronectin fibril biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061800 A supramolecular fiber formed from fibronectin molecules. The fibrils are 5 to 25nm in diameter and can form branched meshworks. GO:0061803 posterior cell cortex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061803 The region that lies just beneath the plasma membrane in the part of a cell that is closest to the posterior as defined by the developing, or existing, anterior/posterior axis. GO:0061802 anterior cell cortex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061802 The region that lies just beneath the plasma membrane in the part of a cell that is closest to the anterior as defined by the developing, or existing, anterior/posterior axis. GO:0061805 mitotic spindle elongation (spindle phase three) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061805 mitotic spindle elongation during mitotic anaphase|mitotic anaphase spindle elongation|mitotic spindle elongation during anaphase The cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B. GO:0061804 mitotic spindle formation (spindle phase one) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061804 mitotic spindle elongation during mitotic prophase|mitotic spindle elongation during prophase|mitotic spindle elongation during prophase and prometaphase The cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase. GO:0061807 positive regulation of DNA recombination at centromere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061807 positive regulation of centromeric recombination Any process that activates or increases the frequency, rate or extent of DNA recombination at the centromere. GO:0061806 regulation of DNA recombination at centromere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061806 regulation of centromeric recombination Any process that modulates the frequency, rate or extent of DNA recombination within centromeric DNA. UBERON:0002682 abducens nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002682 abducens nerve nucleus|nucleus of abducens nerve (VI)|abducent nucleus|abducens VI nucleus|motor nucleus VI|sixth cranial nerve nucleus|abducens motor nuclei|nucleus nervi abducentis|nucleus abducens|abducens motor nucleus|nVI|abducens nucleus proper|nucleus nervi abducentis|nucleus of abducens nerve Nucleus located beneath the floor of the 4th ventricle in the pontine tegmentum, containing motor neurons innervating the lateral rectus muscle of the eye (Brodal, Neurological Anatomy, 3rd ed., 1981, pg 533) GO:0061809 NAD+ nucleotidase, cyclic ADP-ribose generating biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061809 MetaCyc:NADNUCLEOSID-RXN|EC:3.2.2.6 Catalysis of the reaction: NAD+ + H2O = nicotinamide + ADP-ribose that proceeds in a stepwise fashion by ADP-ribosyl cyclase activity followed by cyclic ADP-ribose hydrolase activity. CHEBI:35452 dTDP-L-rhamnose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35452 GO:0061808 negative regulation of DNA recombination at centromere biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061808 negative regulation of centromeric recombination Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination at the centromere. UBERON:0002668 oculomotor nerve root biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002668 oculomotor nerve fibers|oculomotor nerve tract|fibrae nervi oculomotorii|root of oculomotor nerve|central part of oculomotor nerve|3nf Initial segment of the occulomotor nerve as it leaves the midbrain. CHEBI:59410 3-epi-6-deoxocathasterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59410 CHEBI:35465 (Z)-hexadec-7-enoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35465 CHEBI:35464 (Z)-hexadec-11-enoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35464 CHEBI:84475 1-palmitoyl-sn-glycero-3-phosphoglycerol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84475 CHEBI:35467 phosphorodiamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35467 CHEBI:84473 1-alkyl-2-methyl-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84473 CHEBI:35469 antidepressant biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35469 CHEBI:84472 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84472 CHEBI:35468 triazene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35468 CHEBI:84470 1-heptadecanoyl-2-arachidonoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84470 CHEBI:59418 15beta-hydroxyprogesterone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59418 CHEBI:59414 muramyl dipeptide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59414 CHEBI:59412 amino tetrasaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59412 UBERON:0002673 vestibular nuclear complex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002673 nuclei vestibulares|vestibular nuclei|vestibular nucleus|vestibular nuclei in medulla oblongata|nuclei vestibulares in medulla oblongata Nuclear complex containing the vestibular nuclei. CHEBI:59411 (5alpha,22S,24R)-22-hydroxyergostan-3-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59411 CHEBI:84489 1-heptadecanoyl-2-arachidonoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84489 CHEBI:35436 D-glucoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35436 GO:0061821 telomeric D-loop binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061821 telomeric Displacement-loop binding Interacting selectively and non-covalently with a telomeric D-loop. A telomeric D-loop is a three-stranded DNA displacement loop that forms at the site where the telomeric 3' single-stranded DNA overhang (formed of the repeat sequence TTAGGG in mammals) is tucked back inside the double-stranded component of telomeric DNA molecule, thus forming a t-loop or telomeric-loop and protecting the chromosome terminus. CHEBI:84483 1-O-acyl-N-acetylsphingosine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84483 GO:0061820 telomeric D-loop disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061820 A telomere loop disassembly process that results in the disassembly of telomeric D-loops. A telomeric D-loop is a three-stranded DNA displacement loop that forms at the site where the telomeric 3' single-stranded DNA overhang (formed of the repeat sequence TTAGGG in mammals) is tucked back inside the double-stranded component of telomeric DNA molecule, thus forming a t-loop or telomeric-loop and protecting the chromosome terminus. GO:0061823 ring centriole biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061823 A ring-like structure observed at the base of the ciliary cap of insect spermatids. This structure may anchor the axoneme to the ciliary cap membrane and/or act as a diffusion barrier, proposed to be analogous to the annulus of mammalian sperm flagellum. CHEBI:84481 N,O-diacylethanolamine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84481 CHEBI:35438 nickel coordination entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35438 GO:0061822 ciliary cap biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061822 spermatid ciliary cap An intracellular compartmentalized cilium structure found in insect spermatids which is bounded by a membrane derived from the invagination of the cell membrane that remains associated with the primary cilium as it is internalized. The ciliary cap is maintained at the end of the axoneme distal to the centriole and is separated from the cytosolic axoneme/cytoplasm by a putative transition zone, which may extend into the ciliary cap, and include a structure at the base of the ciliary cap termed the ring centriole. GO:0061825 podosome core biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061825 The F-actin-rich core of an adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell. GO:0061824 cytosolic ciliogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061824 intracellular ciliogenesis The process in which an axoneme is exposed entirely or partially to the cytoplasm or by which the cytoplasmic portion is assembled or extended. Cytosolic ciliogenesis can occur following compartmentalized ciliogenesis, in which the cilium is formed within a compartment separated from the cytoplasm. GO:0061827 sperm head biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061827 The part of the late spermatid or spermatozoon that contains the nucleus and acrosome. GO:0061826 podosome ring biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061826 The ring structure surrounding the podosome core, containing proteins such as vinculin and talin. GO:0061829 basal tubulobulbar complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061829 basal TBC Actin-based structures involved in establishing the blood-testis barrier of the Sertoli cell. CHEBI:59403 glutathione amide disulfide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59403 GO:0061828 apical tubulobulbar complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061828 apical TBC Actin-based structures involved in establishing close contact between mature spermatids and Sertoli cells at the luminal end of the Sertoli cell. CHEBI:35443 anthelminthic drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35443 CHEBI:84497 (omega-1)-hydroxy fatty acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84497 CHEBI:35442 antiparasitic agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35442 CHEBI:84496 4-hydroxy-3-all-trans-heptaprenylbenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84496 CHEBI:35444 antinematodal drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35444 GO:0061810 NAD glycohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061810 EC:3.2.2.5|Reactome:R-HSA-9637699 Catalysis of the reaction: NAD+ + H2O = nicotinamide + ADP-ribose without proceeding through a cyclic ADP-ribose intermediate. PO:0006085 root meristem biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0006085 meristema de la raíz (Spanish, exact)|meristematic zone (related)|根分裂組織 (Japanese, exact) A portion of meristem tissue (PO:0009013) that gives rise to a root (PO:0009005). CHEBI:84494 4-hydroxy-3-all-trans-heptaprenylbenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84494 CHEBI:84493 (omega-1)-ethyl fatty acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84493 CHEBI:35446 chlorobiphenyl biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35446 GO:0061812 cyclic ADP-ribose hydrolase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061812 Catalysis of the reaction: cyclic ADP-ribose + H20 = ADP-ribose (ADPR). CHEBI:84492 4-hydroxy-3-all-trans-hexaprenylbenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84492 GO:0061811 ADP-ribosyl cyclase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061811 Catalysis of the reaction: NAD = cyclic ADP-ribose + nicotinamide. GO:0061814 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0061814 PO:0006089 anther primordium biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0006089 primordio de la antera (Spanish, exact)|portion of anther primordium tissue (exact)|葯原基(可視的） (Japanese, exact) A floral structure primordium (PO:0025477) that is committed to the development of an anther (PO:0009066). CHEBI:84490 1-heptadecanoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84490 GO:0061813 obsolete ARID domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061813 OBSOLETE. Interacting selectively and non-covalently with a ARID domain. The AT-rich interaction domain (ARID) is an ~100-amino acid DNA-binding module found in a large number of eukaryotic transcription factors. UBERON:0002653 gracile fasciculus of medulla biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002653 medulla segment of fasciculus gracilis|fasciculus of goll|gracile fascicle (Goll)|Goll's tract|column of Goll|gracile fascicle of medulla|fasciculus gracilis (myelencephali)|fasciculus dorsolateralis gracilis (Golli)|gracile fascicle (Gall)|medulla segment of gracile fasciculus|gracile fasciculus of the medulla|tract of Gall Part of gracile fasiculus located in the medulla PO:0006088 primary sporogenous cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0006088 célula esporógena primaria (Spanish, exact)|一次胞子形成細胞 (Japanese, exact) A native plant cell (PO:0025606) is formed by the division of the male archesporial initial. After several mitotic divisions these cells differentiate into pollen mother cells. GO:0061816 proteaphagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061816 The selective autophagy process that clears 26S proteasomes; homeostatic mechanism within the ubiquitin system that modulates proteolytic capacity and eliminates damaged particles. GO:0061815 ubiquitinyl hydrolase activity, acting on linear ubiquitin biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061815 Met1 linkage specific DUB|linear ubiquitin specific deubiquitinase activity Catalysis of the hydrolysis of ubiquitin units from linear ubiquitin chains. GO:0061818 tRNA folding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061818 The process of assisting in the folding of tRNAs into the correct tertiary structure. GO:0061817 endoplasmic reticulum-plasma membrane tethering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061817 ER-plasma membrane tethering The attachment of an endoplasmic reticulum membrane to the plasma membrane via molecular tethers. CHEBI:35441 antiinfective agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35441 GO:0061819 telomeric DNA-containing double minutes formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061819 TDMs formation A telomere maintenance process that results in the formation of small fragments of circular extrachromosomal DNA elements which contain telomeric DNA. It is speculated that telomeric DNA-containing double minutes are formed through a recombination event between the telomere and chromosome-internal TTAGGG-like sequences. Telomeric DNA-containing double minutes appear as two closely positioned dots in metaphase. CHEBI:35440 (1R,2S)-3-phenylcyclohexa-3,5-diene-1,2-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35440 GO:0071198 Kv4.1-DPP6 channel complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071198 CORUM:600 Kv4.1-DPPX channel complex A voltage-gated potassium channel complex that contains the peptidase-related protein DPP6 associated with the channel via interaction with the Kv alpha subunit 4.1. GO:0071197 Kv4.2-Kv4.3 channel complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071197 CORUM:609 A voltage-gated potassium channel complex that contains the Kv alpha subunits 4.2 and 4.3. GO:0071196 Kv4.3-KChIP1 channel complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071196 CORUM:3091 A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP1 associated with the channel via interaction with the Kv alpha subunit 4.3. GO:0071195 Kv4.2-KChIP4 channel complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071195 CORUM:3090 A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP4 associated with the channel via interaction with the Kv alpha subunit 4.2. GO:0071194 Kv4.2-KChIP3 channel complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071194 CORUM:608 A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP3 associated with the channel via interaction with the Kv alpha subunit 4.2. GO:0071193 Kv4.2-KChIP2 channel complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071193 CORUM:607 A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP2 associated with the channel via interaction with the Kv alpha subunit 4.2. GO:0071192 Kv4.2-KChIP1 channel complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071192 CORUM:606 A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP1 associated with the channel via interaction with the Kv alpha subunit 4.2. GO:0071191 protocadherin-alpha-v7-protocadherin-gamma-b4 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071191 Pcdha7-Pcdhgb2 complex A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-b4, and is involved in the regulation of protein localization to the plasma membrane. GO:0071190 protocadherin-alpha-v7-protocadherin-gamma-b2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071190 Pcdha7-Pcdhgb4 complex A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-b2, and is involved in the regulation of protein localization to the plasma membrane. PATO:0000411 circular biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PATO_0000411 round|rounded A shape quality inhering in a bearer by virtue of the bearer's being such that every part of the surface or the circumference is equidistant from the center. CHEBI:142567 alpha-D-Galp-(1->4)-beta-D-Galp-(1->4)-beta-D-Glcp-yl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142567 CHEBI:142568 beta-D-Galp-(1->3)-beta-D-GalpNAc-(1->3)-alpha-D-Galp-(1->4)-beta-D-Galp-yl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142568 GO:0071199 Kv4.1-DPP10 channel complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071199 CORUM:601 Kv4.1-DPPY channel complex A voltage-gated potassium channel complex that contains the peptidase-related protein DPP10 associated with the channel via interaction with the Kv alpha subunit 4.1. CHEBI:142554 N(omega)-(ADP-D-ribosyl)-L-argininium(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142554 CHEBI:60402 Ins-1-P-Cer(d18:0/24:0) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60402 CHEBI:60405 Ins-1-P-Cer(d18:0/26:0) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60405 CHEBI:60409 Ins-1-P-Cer(d18:0/2-OH-26:0) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60409 CHEBI:142544 tamsulosin(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142544 CHEBI:142549 ent-tamsulosin(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142549 CHEBI:142548 ent-tamsulosin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_142548 CHEBI:60416 Man-beta1-2-Ins-1-P-Cer(d18:0/24:0) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60416 CHEBI:142546 5-(2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl)-2-methoxybenzenesulfonamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_142546 NCBITaxon:1783272 Terrabacteria group organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_1783272 CHEBI:142533 ->4)-alpha-D-Galp-(1->4)-beta-D-Galp-(1->4)-beta-D-Glcp-yl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142533 CHEBI:142532 alpha-Neup5Ac-(2->8)-alpha-Neup5Ac-(2->3)-beta-D-Galp-(1->4)-beta-D-Glcp-yl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_142532 CHEBI:60427 dioleoyl phosphatidic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60427 UBERON:0002600 limbic lobe biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002600 fornicate convolution|grande lobe limbique of Broca|fornicate gyrus|limbic lobe (carpenter)|fornicate lobe|gyrus fornicatus|lobus limbicus Part of cerebral hemisphere located on the medial surface, forming a ring around the brain stem PO:0006036 root epidermis biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0006036 epidermis de la raíz (Spanish, exact)|epiblem (related)|rhizodermis (related)|根表皮 (Japanese, exact) A portion of epidermis (PO:0005679) that is part of a root (PO:0009005). PO:0006035 shoot system epidermis biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0006035 シュート表皮 (Japanese, exact)|epidermis del epiblasto (epiblastema) (Spanish, exact) A portion of epidermis (PO:0005679) that is part of a shoot system (PO:0009006) and arises from the meristem L1 layer (PO:0009020). CHEBI:142522 beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-R group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_142522 CHEBI:142521 beta-D-GalpNAc-(1->4)-[alpha-Neup5Gc-(2->3)]-beta-D-Galp-(1->4)-R group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_142521 CHEBI:60430 2-monolysocardiolipin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60430 CHEBI:60431 2,2'-dilysocardiolipin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60431 CHEBI:59497 beta-D-galactofuranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59497 CHEBI:142525 3-hydroxybutane-1,2,3-tricarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_142525 PO:0006023 bundle sheath biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0006023 維管束鞘 (Japanese, exact)|vaina del haz (Spanish, exact) A portion of ground tissue (PO:0025059) which comprises a layer or layers of cells surrounding the vascular bundles (PO:0005020) of leaves. It may consist of parenchyma (PO:0005421) or sclerenchyma (PO:0005427). CHEBI:142510 isonocardicin A zwitterion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_142510 CHEBI:84404 ceramide 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84404 CHEBI:84403 phytoceramides biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84403 CHEBI:84400 1,1',2-trilinoleoyl-2'-palmitoyl cardiolipin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84400 CHEBI:142518 beta-D-GalNAc-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-yl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142518 CHEBI:142514 ->8)-alpha-Neu5Ac-(2->3)-[beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)]-beta-D-Gal-(1->4)-yl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_142514 CHEBI:60449 mannose-(1D-myo-inositol 1-phosphate)2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60449 CHEBI:142513 oxime anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_142513 CHEBI:60448 mannose-1D-myo-inositol 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60448 PO:0006016 leaf epidermis biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0006016 phyllid epidermis (exact)|葉表皮 (Japanese, exact)|epidermis de la hoja (Spanish, exact)|foliage leaf epidermis (exact) A portion of phyllome epidermis (PO:0025157) that is part of a leaf (PO:0025034). PO:0006015 female archesporial cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0006015 雌胞原細胞 (Japanese, exact)|female archesporial initial (exact)|ovule archesporial cell (narrow)|célula femenina arquesporial (Spanish, exact) An archesporial cell (PO:0030056) that is part of a megasporangium (PO:0025201) and divides to give rise to a megasporocyte (PO:0000431). PO:0006014 male archesporial cell biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0006014 male archesporial initial (exact)|雄性胞原細胞 (Japanese, exact)|anther archesporial cell (narrow)|célula masculina arquesporial (Spanish, exact) An archesporial cell (PO:0030056) that is part of a microsporangium (PO:0025202) and divides to gives rise to a microsporocyte (PO:0020047). CHEBI:84417 1,2-di-palmitoleoyl-2-sn-glycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84417 CHEBI:84414 hexadecanoyl-AMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84414 CHEBI:84412 tetradecanoyl-AMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84412 CHEBI:84411 3-dehydrosphingoid base(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84411 CHEBI:84410 sphingoid base(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84410 CHEBI:60454 Fe-coproporphyrin III biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60454 CHEBI:142508 beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-yl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142508 CHEBI:59475 6-O-acyl-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59475 CHEBI:60459 trans,poly-cis-decaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60459 PO:0006001 phyllome biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0006001 filoma (Spanish, exact)|フィロム、葉(的）器官 (Japanese, exact) A lateral plant organ (PO:0009008) produced by a shoot apical meristem (PO:0020148). PO:0006005 carpel anlagen biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PO_0006005 心皮原基 (Japanese, exact)|esbozo de carpelo (Spanish, exact) A phyllome anlagen (PO:0025430) that will give rise to a carpel primordium (PO:0004703) and is part of a peripheral zone (PO:000225) of a flower meristem (PO:0000229). GO:0046165 alcohol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046165 alcohol anabolism|alcohol synthesis|alcohol formation|alcohol biosynthesis The chemical reactions and pathways resulting in the formation of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom. GO:0071121 alpha9-beta1 integrin-VEGF-D complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071121 ITGA9-ITGB1-FIGF complex A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular endothelial growth factor D. GO:0071120 alpha4-beta1 integrin-CD47 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071120 ITGA4-ITGB1-CB47 complex A protein complex that consists of an alpha4-beta1 integrin complex bound to the cell surface antigen CD47. GO:0046164 alcohol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046164 alcohol degradation|alcohol breakdown|alcohol catabolism The chemical reactions and pathways resulting in the breakdown of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom. GO:0046163 heme C catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046163 heme C breakdown|heme C catabolism|haem C catabolism|haem C catabolic process|heme C degradation The chemical reactions and pathways resulting in the breakdown of heme C, a derivative of heme found in cytochromes c, b4, and f. GO:0046162 heme C metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046162 heme C metabolism|haem C metabolic process|haem C metabolism The chemical reactions and pathways involving heme c, a derivative of heme found in cytochromes c, b4, and f. GO:0046161 heme a catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046161 heme a catabolism|heme a breakdown|haem a catabolism|haem a catabolic process|heme a degradation The chemical reactions and pathways resulting in the breakdown of heme a, a derivative of heme found in cytochrome aa3. GO:1900239 regulation of phenotypic switching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900239 regulation of phenotypic dimorphism Any process that modulates the frequency, rate or extent of phenotypic switching. GO:1900238 regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900238 regulation of metanephric mesenchyme chemotaxis by platelet-derived growth factor receptor-beta signaling pathway|regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signalling pathway Any process that modulates the frequency, rate or extent of regulation of metanephric mesenchymal cell migration, by platelet-derived growth factor receptor-beta signaling pathway. GO:0046160 heme a metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046160 heme a metabolism|haem a metabolism|haem a metabolic process The chemical reactions and pathways involving heme a, a derivative of heme found in cytochrome aa3. GO:1900235 negative regulation of Kit signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900235 negative regulation of Kit signalling pathway|down-regulation of Kit signaling pathway|down regulation of stem cell factor receptor signaling pathway|down-regulation of stem cell factor signaling pathway|negative regulation of stem cell factor signaling pathway|inhibition of Kit signaling pathway|downregulation of stem cell factor receptor signaling pathway|downregulation of stem cell factor signaling pathway|negative regulation of stem cell factor receptor signaling pathway|down-regulation of stem cell factor receptor signaling pathway|down regulation of stem cell factor signaling pathway|down regulation of Kit signaling pathway|downregulation of Kit signaling pathway|inhibition of stem cell factor signaling pathway|inhibition of stem cell factor receptor signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of Kit signaling pathway. GO:1900234 regulation of Kit signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900234 regulation of stem cell factor receptor signaling pathway|regulation of Kit signalling pathway|regulation of stem cell factor signaling pathway Any process that modulates the frequency, rate or extent of Kit signaling pathway. GO:1900237 positive regulation of induction of conjugation with cellular fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900237 up regulation of induction of conjugation with cellular fusion|up-regulation of induction of conjugation with cellular fusion|upregulation of induction of conjugation with cellular fusion Any process that activates or increases the frequency, rate or extent of induction of conjugation with cellular fusion. GO:1900236 positive regulation of Kit signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900236 upregulation of stem cell factor receptor signaling pathway|activation of stem cell factor signaling pathway|positive regulation of Kit signalling pathway|up-regulation of Kit signaling pathway|positive regulation of stem cell factor signaling pathway|up regulation of stem cell factor receptor signaling pathway|up regulation of stem cell factor signaling pathway|positive regulation of stem cell factor receptor signaling pathway|upregulation of Kit signaling pathway|activation of stem cell factor receptor signaling pathway|upregulation of stem cell factor signaling pathway|up-regulation of stem cell factor receptor signaling pathway|up regulation of Kit signaling pathway|activation of Kit signaling pathway|up-regulation of stem cell factor signaling pathway Any process that activates or increases the frequency, rate or extent of Kit signaling pathway. GO:0046169 methanol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046169 methanol biosynthesis|methanol anabolism|methanol synthesis|methanol formation The chemical reactions and pathways resulting in the formation of methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent. GO:1900231 regulation of single-species biofilm formation on inanimate substrate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900231 Any process that modulates the frequency, rate or extent of single-species biofilm formation on inanimate substrate. GO:0046168 glycerol-3-phosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046168 glycerol-3-phosphate degradation|glycerol-3-phosphate breakdown|glycerol-3-phosphate catabolism The chemical reactions and pathways resulting in the breakdown of glycerol-3-phosphate, a phosphoric monoester of glycerol. GO:1900230 positive regulation of single-species biofilm formation in or on host organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900230 up-regulation of single-species biofilm formation in or on host organism|upregulation of single-species biofilm formation in or on host organism|up regulation of single-species biofilm formation in or on host organism|activation of single-species biofilm formation in or on host organism Any process that activates or increases the frequency, rate or extent of single-species biofilm formation in or on host organism. GO:0046167 glycerol-3-phosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046167 glycerol-3-phosphate biosynthesis|glycerol-3-phosphate anabolism|glycerol-3-phosphate synthesis|glycerol-3-phosphate formation The chemical reactions and pathways resulting in the formation of glycerol-3-phosphate, a phosphoric monoester of glycerol. GO:1900233 positive regulation of single-species biofilm formation on inanimate substrate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900233 upregulation of single-species biofilm formation on inanimate substrate|up regulation of single-species biofilm formation on inanimate substrate|activation of single-species biofilm formation on inanimate substrate|up-regulation of single-species biofilm formation on inanimate substrate Any process that activates or increases the frequency, rate or extent of single-species biofilm formation on inanimate substrate. GO:0046166 glyceraldehyde-3-phosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046166 glyceraldehyde-3-phosphate biosynthesis|glyceraldehyde 3-phosphate biosynthetic process|glyceraldehyde 3-phosphate biosynthesis|glyceraldehyde-3-phosphate anabolism|glyceraldehyde-3-phosphate synthesis|glyceraldehyde-3-phosphate formation The chemical reactions and pathways resulting in the formation of glyceraldehyde-3-phosphate, an important intermediate in glycolysis. GO:1900232 negative regulation of single-species biofilm formation on inanimate substrate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900232 down regulation of single-species biofilm formation on inanimate substrate|downregulation of single-species biofilm formation on inanimate substrate|down-regulation of single-species biofilm formation on inanimate substrate|inhibition of single-species biofilm formation on inanimate substrate Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation on inanimate substrate. GO:1900240 negative regulation of phenotypic switching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900240 negative regulation of phenotypic dimorphism|down-regulation of phenotypic dimorphism|down-regulation of phenotypic switching|downregulation of phenotypic switching|inhibition of phenotypic dimorphism|down regulation of phenotypic switching|inhibition of phenotypic switching|down regulation of phenotypic dimorphism|downregulation of phenotypic dimorphism Any process that stops, prevents or reduces the frequency, rate or extent of phenotypic switching. GO:0071129 alphaV-beta3 integrin-LPP3 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071129 ITGAV-ITGB3-PPAP2B complex A protein complex that consists of an alphaV-beta3 integrin complex bound to lipid phosphate phosphohydrolase-3. GO:0071128 alpha5-beta1 integrin-osteopontin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071128 ITGA5-ITGB1-SPP1 complex A protein complex that consists of an alpha5-beta1 integrin complex bound to osteopontin. GO:0071127 alpha9-beta1 integrin-osteopontin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071127 ITGA9-ITGB1-SPP1 complex A protein complex that consists of an alpha9-beta1 integrin complex bound to osteopontin. GO:0071126 alphaV-beta6 integrin-osteopontin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071126 ITGAV-ITGB6-SPP1 complex A protein complex that consists of an alphaV-beta6 integrin complex bound to osteopontin. GO:0071125 alphaV-beta3 integrin-EGFR complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071125 ITGAV-ITGB3-EGFR complex A protein complex that consists of an alphaV-beta3 integrin complex bound to epidermal growth factor receptor. GO:0071124 alpha1-beta1 integrin-tyrosine-protein phosphatase non-receptor type 2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071124 ITGA1-ITGB1-PTPN2 complex A protein complex that consists of an alpha1-beta1 integrin complex bound to tyrosine-protein phosphatase non-receptor type 2. GO:0071123 alpha9-beta1 integrin-VEGF-C complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071123 ITGA9-ITGB1-VEGFC complex A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular endothelial growth factor C. GO:0071122 alpha9-beta1 integrin-VEGF-A complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071122 ITGA9-ITGB1-VEGFA complex A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular endothelial growth factor A. GO:0046176 aldonic acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046176 aldonic acid catabolism|aldonic acid degradation|aldonic acid breakdown The chemical reactions and pathways resulting in the breakdown of aldonic acid, a monocarboxylic acid with a chain of three or more carbon atoms, derived from an aldose by oxidation of the aldehydic group. GO:0071110 histone biotinylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071110 The modification of a histone by the addition of a biotinyl group. GO:0046175 aldonic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046175 aldonic acid anabolism|aldonic acid biosynthesis|aldonic acid synthesis|aldonic acid formation The chemical reactions and pathways resulting in the formation of aldonic acid, a monocarboxylic acid with a chain of three or more carbon atoms, derived from an aldose by oxidation of the aldehydic group. GO:0046174 polyol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046174 polyol catabolism|polyhydric alcohol catabolic process|polyol degradation|polyol breakdown The chemical reactions and pathways resulting in the breakdown of a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms. GO:0046173 polyol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046173 polyol biosynthesis|polyol anabolism|polyol synthesis|polyol formation|polyhydric alcohol biosynthetic process The chemical reactions and pathways resulting in the formation of a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms. GO:0046172 octanol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046172 octanol catabolism|octanol degradation|octanol breakdown The chemical reactions and pathways resulting in the breakdown of octanol, the 8-carbon alcohol with the formula C8H17OH. GO:1900249 positive regulation of cytoplasmic translational elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900249 up regulation of cytoplasmic translational elongation|upregulation of cytoplasmic translational elongation|up-regulation of cytoplasmic translational elongation|activation of cytoplasmic translational elongation Any process that activates or increases the frequency, rate or extent of cytoplasmic translational elongation. GO:0046171 octanol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046171 octanol biosynthesis|octanol anabolism|octanol synthesis|octanol formation The chemical reactions and pathways resulting in the formation of octanol, the 8-carbon alcohol with the formula C8H17OH. GO:0046170 methanol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046170 methanol degradation|methanol catabolism|methanol breakdown The chemical reactions and pathways resulting in the breakdown of methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent. GO:1900246 positive regulation of RIG-I signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900246 up-regulation of RIG-I signaling pathway|up regulation of DDX58 signaling pathway|positive regulation of DDX58 signaling pathway|activation of DDX58 signaling pathway|positive regulation of retinoic acid inducible gene I signaling pathway|upregulation of RIG-I signaling pathway|positive regulation of RIG-I signalling pathway|up regulation of retinoic acid inducible gene I signaling pathway|up-regulation of DDX58 signaling pathway|up regulation of RIG-I signaling pathway|upregulation of retinoic acid inducible gene I signaling pathway|activation of RIG-I signaling pathway|upregulation of DDX58 signaling pathway|up-regulation of retinoic acid inducible gene I signaling pathway|activation of retinoic acid inducible gene I signaling pathway Any process that activates or increases the frequency, rate or extent of RIG-I signaling pathway. GO:1900245 positive regulation of MDA-5 signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900245 upregulation of IFIH1 signaling pathway|upregulation of MDA-5 signaling pathway|up-regulation of melanoma differentiation-associated gene 5 signaling pathway|activation of melanoma differentiation-associated gene 5 signaling pathway|upregulation of MDA5 signaling pathway|up regulation of IFIH1 signaling pathway|activation of IFIH1 signaling pathway|positive regulation of IFIH1 signaling pathway|up regulation of MDA-5 signaling pathway|activation of MDA-5 signaling pathway|positive regulation of MDA-5 signalling pathway|positive regulation of melanoma differentiation-associated gene 5 signaling pathway|up-regulation of MDA5 signaling pathway|up regulation of melanoma differentiation-associated gene 5 signaling pathway|up-regulation of IFIH1 signaling pathway|activation of MDA5 signaling pathway|up-regulation of MDA-5 signaling pathway|upregulation of melanoma differentiation-associated gene 5 signaling pathway|positive regulation of MDA5 signaling pathway|up regulation of MDA5 signaling pathway Any process that activates or increases the frequency, rate or extent of MDA-5 signaling pathway. GO:1900248 negative regulation of cytoplasmic translational elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900248 downregulation of cytoplasmic translational elongation|down regulation of cytoplasmic translational elongation|inhibition of cytoplasmic translational elongation|down-regulation of cytoplasmic translational elongation Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational elongation. GO:1900247 regulation of cytoplasmic translational elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900247 Any process that modulates the frequency, rate or extent of cytoplasmic translational elongation. GO:1900242 regulation of synaptic vesicle endocytosis biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_1900242 regulation of synaptic vesicle retrieval Any process that modulates the frequency, rate or extent of synaptic vesicle endocytosis. GO:0061791 GTPase motor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061791 Catalysis of the generation of force resulting either in movement along a microfilament or microtubule, or in torque resulting in membrane scission, coupled to the hydrolysis of GTP. GO:0061790 dense core granule docking biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061790 The initial attachment of a dense core granule membrane to the plasma membrane. GO:0046179 keto-D-gluconate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046179 keto-D-gluconate anabolism|keto-D-gluconate synthesis|keto-D-gluconate formation|keto-D-gluconate biosynthesis The chemical reactions and pathways resulting in the formation of keto-D-gluconate, the anion of keto-D-gluconic acid, an aldonic acid derived from glucose. GO:1900241 positive regulation of phenotypic switching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900241 activation of phenotypic dimorphism|up-regulation of phenotypic dimorphism|up regulation of phenotypic switching|upregulation of phenotypic dimorphism|upregulation of phenotypic switching|up regulation of phenotypic dimorphism|positive regulation of phenotypic dimorphism|activation of phenotypic switching|up-regulation of phenotypic switching Any process that activates or increases the frequency, rate or extent of phenotypic switching. GO:1900244 positive regulation of synaptic vesicle endocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900244 activation of synaptic vesicle endocytosis|up-regulation of synaptic vesicle retrieval|up regulation of synaptic vesicle endocytosis|activation of synaptic vesicle retrieval|positive regulation of synaptic vesicle retrieval|up regulation of synaptic vesicle retrieval|upregulation of synaptic vesicle endocytosis|up-regulation of synaptic vesicle endocytosis|upregulation of synaptic vesicle retrieval Any process that activates or increases the frequency, rate or extent of synaptic vesicle endocytosis. GO:0061793 chromatin lock complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061793 IntAct:EBI-11792170|IntAct:EBI-11790939 nucleosome bridging complex A chromatin silencing complex that binds and bridges separate nucleosomal histones resulting in heterochromatin assembly and chromatin looping. GO:0046178 D-gluconate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046178 D-gluconate synthesis|D-gluconate formation|D-gluconate biosynthesis|D-gluconate anabolism The chemical reactions and pathways resulting in the formation of D-gluconate, the anion of D-gluconic acid, the aldonic acid derived from glucose. GO:1900243 negative regulation of synaptic vesicle endocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900243 inhibition of synaptic vesicle retrieval|down-regulation of synaptic vesicle endocytosis|negative regulation of synaptic vesicle retrieval|down-regulation of synaptic vesicle retrieval|downregulation of synaptic vesicle endocytosis|down regulation of synaptic vesicle endocytosis|inhibition of synaptic vesicle endocytosis|downregulation of synaptic vesicle retrieval|down regulation of synaptic vesicle retrieval Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle endocytosis. GO:0046177 D-gluconate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046177 MetaCyc:GLUCONSUPER-PWY D-gluconate degradation|D-gluconate breakdown|D-gluconate catabolism The chemical reactions and pathways resulting in the breakdown of D-gluconate, the anion of D-gluconic acid, the aldonic acid derived from glucose. GO:0061792 secretory granule maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061792 Steps required to transform an immature secretory vesicle into a mature secretory vesicle. Typically proceeds through homotypic membrane fusion and membrane remodelling. GO:0061795 Golgi lumen acidification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061795 Any process that reduces the pH of the Golgi lumen, measured by the concentration of the hydrogen ion. GO:0061794 conidium development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061794 The process whose specific outcome is the progression of conidium over time, from its formation to the mature structure. Conidia are non-motile spores produced via mitotic asexual reproduction in higher fungi; they are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus. GO:0061797 pH-gated chloride channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061797 A gated channel activity that enables the transmembrane transfer of a chloride ion by a channel that opens in response to a change in pH. GO:0061796 membrane addition at site of mitotic cytokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061796 A mitotic cell cycle process involved in the net addition of membrane at the site of cytokinesis; includes vesicle recruitment and fusion, local lipid synthesis and insertion. GO:0061799 cyclic pyranopterin monophosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061799 MetaCyc:RXN-17809|RHEA:49580|EC:4.6.1.17 Catalysis of the reaction: (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic pyranopterin phosphate + diphosphate. GO:0061798 GTP 3',8'-cyclase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061798 EC:4.1.99.22|MetaCyc:RXN-8340|RHEA:49576 Catalysis of the reaction: GTP=(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate. GO:0071119 alpha7-beta1 integrin-nicotinamide riboside kinase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071119 ITGA7-ITGB1-ITGB1BP3 complex A protein complex that consists of an alpha7-beta1 integrin complex bound to nicotinamide riboside kinase 2 (also known as muscle integrin binding protein, MIBP). GO:0071118 alphaV-beta3 integrin-NOV complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071118 ITGAV-ITGB3-FN-1-NOV complex A protein complex that consists of an alphaV-beta3 integrin complex bound to the extracellular matrix protein NOV. GO:0071117 alpha5-beta1 integrin-fibronectin-NOV complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071117 ITGA5-ITGB1-FN-1-NOV complex A protein complex that consists of an alpha5-beta1 integrin complex bound to fibronectin and the extracellular matrix protein NOV. GO:0071116 alpha6-beta1 integrin-CYR61 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071116 ITGA6-ITGB1-CYR61 complex A protein complex that consists of an alpha6-beta1 integrin complex bound to CYR61, a cysteine-rich protein involved in angiogenesis. GO:0071115 alpha5-beta1 integrin-endostatin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071115 ITGA5-ITGB1-CAL4A3 complex A protein complex that consists of an alpha5-beta1 integrin complex bound to endostatin, the NC1 domain of the alpha1 chain of type XVIII collagen. GO:0071114 alphaV-beta3 integrin-tumstatin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071114 ITGAV-ITGB3-COL4A3 complex A protein complex that consists of an alphaV-beta3 integrin complex bound to tumstatin, the NC1 domain of the alpha3 chain of type IV collagen. GO:0071113 alphaIIb-beta3 integrin-ICAM-4 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071113 ITGAIIb-ITGB3-ICAM4 complex A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell adhesion molecule ICAM-4. GO:0071112 alpha4-beta4 integrin-EMILIN-1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071112 ITGA4-ITGB4-EMILIN1 complex A protein complex that consists of an alpha4-beta4 integrin complex bound to EMILIN-1 (ElastinMicrofibril Interface Located ProteIN). GO:0071111 cyclic-guanylate-specific phosphodiesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071111 RHEA:24902|EC:3.1.4.52|MetaCyc:RXN0-4181|KEGG_REACTION:R08991 VieA|cyclic bis(3->5')diguanylate phosphodiesterase activity|c-di-GMP phosphodiesterase activity|PDEA1|phosphodiesterase A1 activity|c-di-GMP-specific phosphodiesterase activity Catalysis of the reaction: cyclic di-3',5'-guanylate + H(2)O = 5'-phosphoguanylyl(3'->5')guanosine + H(+). GO:0046187 acetaldehyde catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046187 acetaldehyde degradation|acetaldehyde breakdown|acetaldehyde catabolism The chemical reactions and pathways resulting in the breakdown of acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol. GO:0071143 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0071143 GO:0071142 homomeric SMAD protein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071142 IntAct:EBI-10043504|IntAct:EBI-10043586|IntAct:EBI-10043574|IntAct:EBI-10828213|IntAct:EBI-10828300|IntAct:EBI-10043549 SMAD1 homotrimer complex|SMAD2 homotrimer complex|SMAD3 protein complex|SMAD3 homotrimer complex|SMAD2 protein complex|SMAD1 protein complex A protein complex composed of a single type of SMAD family proteins. In the absence of Smad4, phosphorylation of R-SMADs results in their homotrimerization. However, these complexes do not appear to import into the nucleus and are assumed to be transcriptionally inactive. GO:0046186 acetaldehyde biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046186 acetaldehyde anabolism|acetaldehyde synthesis|acetaldehyde formation|acetaldehyde biosynthesis The chemical reactions and pathways resulting in the formation of acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol. GO:0046185 aldehyde catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046185 aldehyde catabolism|aldehyde degradation|aldehyde breakdown The chemical reactions and pathways resulting in the breakdown of aldehydes, any organic compound with the formula R-CH=O. GO:0071141 SMAD protein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071141 SMAD complex A protein complex that consists of only SMAD proteins; may be homomeric or heteromeric. Heteromeric complexes act as transcription factors while homomeric complexes exist but are transcriptionally inactive. Hetero- versus homotrimerization is largely enthalpy driven. GO:0046184 aldehyde biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046184 aldehyde anabolism|aldehyde synthesis|aldehyde formation|aldehyde biosynthesis The chemical reactions and pathways resulting in the formation of aldehydes, any organic compound with the formula R-CH=O. OBO:GOCHE_63046 substance with emulsifier role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_63046 GO:0071140 resolution of mitotic recombination intermediates biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071140 The cleavage and rejoining of intermediates, mitotic recombination to produce two intact molecules in which genetic material has been exchanged. GO:0046183 L-idonate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046183 L-idonate degradation|L-idonate breakdown|L-idonate catabolism The chemical reactions and pathways resulting in the breakdown of L-idonate, the anion of idonic acid, an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose. GO:0046182 L-idonate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046182 L-idonate biosynthesis|L-idonate anabolism|L-idonate synthesis|L-idonate formation The chemical reactions and pathways resulting in the formation of L-idonate, the anion of idonic acid, an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose. GO:0046181 ketogluconate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046181 ketogluconate degradation|ketogluconate breakdown|ketogluconate catabolism The chemical reactions and pathways resulting in the breakdown of ketogluconate, the anion of ketogluconic acid, an aldonic acid derived from glucose containing a ketonic carbonyl group. GO:0046180 ketogluconate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046180 ketogluconate anabolism|ketogluconate biosynthesis|ketogluconate synthesis|ketogluconate formation The chemical reactions and pathways resulting in the formation of ketogluconate, the anion of ketogluconic acid, an aldonic acid derived from glucose containing a ketonic carbonyl group. GO:1900257 negative regulation of beta1-adrenergic receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900257 down-regulation of beta1-adrenergic receptor activity|downregulation of beta1 adrenoceptor|down regulation of beta1 adrenoceptor|downregulation of beta1-adrenergic receptor activity|down regulation of beta1-adrenergic receptor activity|inhibition of beta1-adrenergic receptor activity|inhibition of beta1 adrenoceptor|negative regulation of beta1 adrenoceptor|down-regulation of beta1 adrenoceptor Any process that stops, prevents or reduces the frequency, rate or extent of beta1-adrenergic receptor activity. GO:1900256 regulation of beta1-adrenergic receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900256 regulation of beta1 adrenoceptor Any process that modulates the frequency, rate or extent of beta1-adrenergic receptor activity. GO:1900259 regulation of RNA-directed 5'-3' RNA polymerase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900259 regulation of ribonucleic synthetase activity|regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|regulation of RNA-directed RNA polymerase activity|regulation of RNA synthetase activity|regulation of RNA-dependent RNA polymerase activity|regulation of RNA replicase activity|regulation of 3D polymerase activity|regulation of ribonucleic replicase activity|regulation of RNA-dependent ribonucleate nucleotidyltransferase activity|regulation of RNA nucleotidyltransferase (RNA-directed) activity|regulation of phage f2 replicase|regulation of Q-beta replicase activity|regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity|regulation of ribonucleic acid replicase activity|regulation of PB1 proteins|regulation of polymerase L|regulation of transcriptase|regulation of RDRP|regulation of PB2 proteins|regulation of RNA-dependent RNA replicase activity Any process that modulates the frequency, rate or extent of RNA-directed 5'-3' RNA polymerase activity. GO:1900258 positive regulation of beta1-adrenergic receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900258 positive regulation of beta1 adrenoceptor|up regulation of beta1 adrenoceptor|up regulation of beta1-adrenergic receptor activity|upregulation of beta1 adrenoceptor|upregulation of beta1-adrenergic receptor activity|up-regulation of beta1 adrenoceptor|up-regulation of beta1-adrenergic receptor activity|activation of beta1-adrenergic receptor activity|activation of beta1 adrenoceptor Any process that activates or increases the frequency, rate or extent of beta1-adrenergic receptor activity. GO:0046189 phenol-containing compound biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046189 phenol-containing compound anabolism|phenol-containing compound synthesis|phenol-containing compound formation|phenol-containing compound biosynthesis The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring. GO:0046188 methane catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046188 methane degradation|methane breakdown|methane catabolism The chemical reactions and pathways resulting in the breakdown of methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes. GO:1900260 negative regulation of RNA-directed 5'-3' RNA polymerase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900260 inhibition of ribonucleic replicase activity|downregulation of Q-beta replicase activity|inhibition of RNA-dependent ribonucleate nucleotidyltransferase activity|inhibition of ribonucleic synthetase activity|downregulation of ribonucleic acid-dependent ribonucleic acid polymerase activity|inhibition of RNA nucleotidyltransferase (RNA-directed) activity|down regulation of ribonucleic acid replicase activity|inhibition of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|negative regulation of RNA-directed RNA polymerase activity|downregulation of PB1 proteins|downregulation of polymerase L|inhibition of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|downregulation of RDRP|downregulation of PB2 proteins|down regulation of transcriptase|negative regulation of RNA replicase activity|down-regulation of RNA replicase activity|downregulation of RNA-dependent RNA replicase activity|downregulation of ribonucleic acid replicase activity|inhibition of phage f2 replicase|down regulation of polymerase L|down-regulation of RNA-directed RNA polymerase activity|inhibition of RNA synthetase activity|down regulation of PB1 proteins|down regulation of PB2 proteins|down regulation of RDRP|downregulation of transcriptase|down regulation of ribonucleic synthetase activity|inhibition of RNA-dependent RNA polymerase activity|negative regulation of Q-beta replicase activity|down-regulation of Q-beta replicase activity|down regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|down regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|down regulation of RNA-dependent RNA replicase activity|negative regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity|down-regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity|down-regulation of 3D polymerase activity|negative regulation of 3D polymerase activity|negative regulation of ribonucleic replicase activity|downregulation of ribonucleic synthetase activity|down-regulation of ribonucleic replicase activity|negative regulation of RNA nucleotidyltransferase (RNA-directed) activity|down-regulation of RNA nucleotidyltransferase (RNA-directed) activity|downregulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|negative regulation of RNA-dependent ribonucleate nucleotidyltransferase activity|down-regulation of RNA-dependent ribonucleate nucleotidyltransferase activity|inhibition of polymerase L|downregulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|down regulation of RNA synthetase activity|inhibition of PB1 proteins|inhibition of PB2 proteins|down regulation of RNA-dependent RNA polymerase activity|inhibition of RDRP|downregulation of RNA replicase activity|down-regulation of ribonucleic acid replicase activity|negative regulation of ribonucleic acid replicase activity|downregulation of RNA-directed RNA polymerase activity|inhibition of RNA-dependent RNA replicase activity|down-regulation of transcriptase|negative regulation of transcriptase|down-regulation of phage f2 replicase|downregulation of RNA synthetase activity|negative regulation of phage f2 replicase|downregulation of RNA-dependent RNA polymerase activity|down regulation of RNA replicase activity|downregulation of 3D polymerase activity|down regulation of RNA-directed RNA polymerase activity|down-regulation of ribonucleic synthetase activity|downregulation of ribonucleic replicase activity|inhibition of Q-beta replicase activity|negative regulation of ribonucleic synthetase activity|inhibition of RNA-directed RNA polymerase activity|negative regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|downregulation of RNA nucleotidyltransferase (RNA-directed) activity|inhibition of ribonucleic acid-dependent ribonucleic acid polymerase activity|downregulation of RNA-dependent ribonucleate nucleotidyltransferase activity|down-regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|negative regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|down-regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|down regulation of 3D polymerase activity|down regulation of ribonucleic replicase activity|inhibition of RNA replicase activity|negative regulation of PB1 proteins|down regulation of RNA-dependent ribonucleate nucleotidyltransferase activity|down regulation of RNA nucleotidyltransferase (RNA-directed) activity|negative regulation of polymerase L|down-regulation of PB1 proteins|down-regulation of polymerase L|negative regulation of RNA synthetase activity|down-regulation of RNA synthetase activity|down-regulation of RDRP|negative regulation of PB2 proteins|downregulation of phage f2 replicase|inhibition of ribonucleic acid replicase activity|down-regulation of PB2 proteins|negative regulation of RDRP|negative regulation of RNA-dependent RNA polymerase activity|down-regulation of RNA-dependent RNA polymerase activity|down regulation of Q-beta replicase activity|down-regulation of RNA-dependent RNA replicase activity|inhibition of transcriptase|negative regulation of RNA-dependent RNA replicase activity|down regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity|down regulation of phage f2 replicase|inhibition of 3D polymerase activity Any process that stops, prevents or reduces the frequency, rate or extent of RNA-directed 5'-3' RNA polymerase activity. GO:1900262 regulation of DNA-directed DNA polymerase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900262 regulation of eta DNA polymerase activity|regulation of DNA polymerase II|regulation of DNA polymerase alpha|regulation of deoxyribonucleic polymerase I|regulation of Taq DNA polymerase|regulation of DNA replicase activity|regulation of mu DNA polymerase activity|regulation of lambda DNA polymerase activity|regulation of nu DNA polymerase activity|regulation of DNA duplicase activity|regulation of kappa DNA polymerase activity|regulation of epsilon DNA polymerase activity|regulation of DNA polymerase V activity|regulation of sequenase|regulation of sigma DNA polymerase activity|regulation of DNA-dependent DNA polymerase activity|regulation of deoxyribonucleic acid duplicase activity|regulation of deoxyribonucleic duplicase activity|regulation of Tca DNA polymerase|regulation of DNA polymerase beta|regulation of zeta DNA polymerase activity|regulation of alpha DNA polymerase activity|regulation of theta DNA polymerase activity|regulation of Klenow fragment|regulation of gamma DNA-directed DNA polymerase activity|regulation of DNA polymerase III|regulation of DNA polymerase I|regulation of duplicase|regulation of DNA polymerase gamma|regulation of iota DNA polymerase activity|regulation of Taq Pol I|regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|regulation of delta DNA polymerase activity|regulation of beta DNA polymerase activity|regulation of DNA nucleotidyltransferase (DNA-directed) activity Any process that modulates the frequency, rate or extent of DNA-directed DNA polymerase activity. GO:1900261 positive regulation of RNA-directed 5'-3' RNA polymerase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900261 positive regulation of PB2 proteins|positive regulation of RDRP|up-regulation of RNA replicase activity|upregulation of ribonucleic acid replicase activity|up regulation of polymerase L|up-regulation of RNA-directed RNA polymerase activity|upregulation of transcriptase|up regulation of PB1 proteins|up regulation of PB2 proteins|positive regulation of RNA-dependent RNA replicase activity|activation of RNA-directed RNA polymerase activity|up regulation of RDRP|upregulation of phage f2 replicase|up-regulation of RNA synthetase activity|up regulation of Q-beta replicase activity|up regulation of RNA-dependent RNA replicase activity|up-regulation of RNA-dependent RNA polymerase activity|up-regulation of 3D polymerase activity|up regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity|positive regulation of Q-beta replicase activity|upregulation of ribonucleic synthetase activity|up-regulation of ribonucleic replicase activity|activation of RNA replicase activity|up-regulation of RNA nucleotidyltransferase (RNA-directed) activity|up-regulation of RNA-dependent ribonucleate nucleotidyltransferase activity|upregulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|positive regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity|upregulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|positive regulation of RNA-directed RNA polymerase activity|up regulation of ribonucleic acid replicase activity|activation of Q-beta replicase activity|upregulation of PB1 proteins|positive regulation of RNA replicase activity|upregulation of polymerase L|activation of 3D polymerase activity|up regulation of transcriptase|upregulation of RDRP|activation of ribonucleic replicase activity|upregulation of PB2 proteins|positive regulation of ribonucleic acid replicase activity|up-regulation of phage f2 replicase|activation of ribonucleic acid-dependent ribonucleic acid polymerase activity|upregulation of RNA synthetase activity|positive regulation of transcriptase|up regulation of RNA replicase activity|activation of RNA nucleotidyltransferase (RNA-directed) activity|activation of RNA-dependent ribonucleate nucleotidyltransferase activity|upregulation of RNA-dependent RNA polymerase activity|up regulation of RNA-directed RNA polymerase activity|upregulation of RNA-dependent RNA replicase activity|up regulation of ribonucleic synthetase activity|positive regulation of 3D polymerase activity|up-regulation of Q-beta replicase activity|up regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|activation of ribonucleic acid replicase activity|positive regulation of ribonucleic replicase activity|up regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|up regulation of 3D polymerase activity|positive regulation of RNA-dependent ribonucleate nucleotidyltransferase activity|activation of transcriptase|positive regulation of ribonucleic synthetase activity|activation of phage f2 replicase|up-regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity|positive regulation of RNA nucleotidyltransferase (RNA-directed) activity|up regulation of ribonucleic replicase activity|positive regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|up-regulation of PB1 proteins|positive regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|up-regulation of polymerase L|up regulation of RNA-dependent ribonucleate nucleotidyltransferase activity|up regulation of RNA nucleotidyltransferase (RNA-directed) activity|up-regulation of PB2 proteins|up-regulation of RDRP|up regulation of RNA synthetase activity|up-regulation of ribonucleic acid replicase activity|up-regulation of RNA-dependent RNA replicase activity|up regulation of RNA-dependent RNA polymerase activity|upregulation of RNA replicase activity|activation of ribonucleic synthetase activity|positive regulation of phage f2 replicase|up-regulation of transcriptase|positive regulation of RNA synthetase activity|upregulation of RNA-directed RNA polymerase activity|activation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|positive regulation of RNA-dependent RNA polymerase activity|activation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|up regulation of phage f2 replicase|upregulation of Q-beta replicase activity|activation of PB1 proteins|activation of polymerase L|activation of RDRP|activation of PB2 proteins|upregulation of ribonucleic acid-dependent ribonucleic acid polymerase activity|upregulation of 3D polymerase activity|upregulation of ribonucleic replicase activity|up-regulation of ribonucleic synthetase activity|activation of RNA synthetase activity|activation of RNA-dependent RNA replicase activity|activation of RNA-dependent RNA polymerase activity|upregulation of RNA nucleotidyltransferase (RNA-directed) activity|up-regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|upregulation of RNA-dependent ribonucleate nucleotidyltransferase activity|positive regulation of polymerase L|up-regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|positive regulation of PB1 proteins Any process that activates or increases the frequency, rate or extent of RNA-directed 5'-3' RNA polymerase activity. GO:0046190 aerobic phenol-containing compound biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046190 aerobic phenol-containing compound biosynthesis|aerobic phenol-containing compound anabolism|aerobic phenol-containing compound synthesis|aerobic phenol-containing compound formation The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen. GO:0071149 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0071149 GO:0071148 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0071148 GO:0071147 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0071147 GO:0071146 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0071146 GO:0071145 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0071145 GO:0071144 heteromeric SMAD protein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071144 IntAct:EBI-10021614|IntAct:EBI-9990274|IntAct:EBI-10043452|IntAct:EBI-9826300|IntAct:EBI-10127301|IntAct:EBI-9826270|IntAct:EBI-10828741|IntAct:EBI-9692430 SMAD2-SMAD3-SMAD4 protein complex|SMAD3-SMAD4 protein complex|SMAD1-SMAD4 protein complex|SMAD2-SMAD4 protein complex A protein complex composed of SMAD family proteins, a transcription factor complex which binds to the promoters of target genes and recruits co-activators and histone acetyltransferases, facilitating transcription. Phosphorylation of the non-SMAD4 subunit(s) enables binding of SMAD4 to form heteromeric complexes that enter the nucleus to initiate gene transcription. DNA-binding specificity is conferred by other transcription factors binding to SMAD complexes. Interactions with coactivators or corepressors modulate their transcriptional activity. Can be heterotrimeric or heterodimeric. GO:0071132 alphaX-beta2 integrin-ICAM-4 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071132 ITGAX-ITGB2-ICAM4 complex A protein complex that consists of an alphaX-beta2 integrin complex bound to intercellular adhesion molecule 4. GO:0046198 obsolete cresol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046198 cresol anabolism|cresol biosynthetic process|cresol biosynthesis|cresol synthesis|cresol formation OBSOLETE. The chemical reactions and pathways resulting in the formation of cresol, a mixture of the aromatic alcohol isoforms o-, p-, and m-cresol, which is obtained from coal tar or petroleum. The isomers are used as disinfectants, textile scouring agents, surfactants and as intermediates in the manufacture of salicylaldehyde, coumarin, and herbicides as well as being a major component of creosote. GO:0071131 alphaV-beta3 integrin-laminin alpha-4 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071131 ITGAV-ITGB3-LAMA4 complex A protein complex that consists of an alphaV-beta3 integrin complex bound to laminin alpha-4. GO:0046197 orcinol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046197 orcinol anabolism|orcinol synthesis|orcinol formation|orcinol biosynthesis The chemical reactions and pathways resulting in the formation of orcinol (5-methyl-1,3-benzenediol), an aromatic compound derived from the fermentation of lichen and synthesized by some higher plants. GO:0046196 4-nitrophenol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046196 4-nitrophenol degradation|4-nitrophenol breakdown|4-nitrophenol catabolism The chemical reactions and pathways resulting in the breakdown of 4-nitrophenol, a nitroaromatic compound which is used in the production of dyes, leather treatment agents, fungicides and as an intermediate in the production of the insecticide parathion. GO:0071130 alpha5-beta1 integrin-LPP3 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071130 ITGA5-ITGB1-PPAP2B complex A protein complex that consists of an alpha5-beta1 integrin complex bound to lipid phosphate phosphohydrolase-3. GO:0046195 obsolete 4-nitrophenol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046195 4-nitrophenol anabolism|4-nitrophenol biosynthesis|4-nitrophenol biosynthetic process|4-nitrophenol synthesis|4-nitrophenol formation OBSOLETE. The chemical reactions and pathways resulting in the formation of 4-nitrophenol, a nitroaromatic compound which is used in the production of dyes, leather treatment agents, fungicides and as an intermediate in the production of the insecticide parathion. GO:0046194 obsolete pentachlorophenol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046194 pentachlorophenol biosynthesis|pentachlorophenol biosynthetic process|pentachlorophenol anabolism|pentachlorophenol synthesis|pentachlorophenol formation OBSOLETE. The chemical reactions and pathways resulting in the formation of pentachlorophenol, a chlorinated insecticide and fungicide used primarily to protect timber from fungal rot and wood boring insects. Pentachlorophenol is significantly toxic to mammals, plants, and many microorganisms. GO:0046193 anaerobic phenol-containing compound catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046193 anaerobic phenol-containing compound breakdown|anaerobic phenol-containing compound catabolism|anaerobic phenol-containing compound degradation The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen. GO:0046192 anaerobic phenol-containing compound biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046192 anaerobic phenol-containing compound anabolism|anaerobic phenol-containing compound synthesis|anaerobic phenol-containing compound formation|anaerobic phenol-containing compound biosynthesis The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen. GO:0046191 aerobic phenol-containing compound catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046191 aerobic phenol-containing compound catabolism|aerobic phenol-containing compound degradation|aerobic phenol-containing compound breakdown The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen. GO:1900268 regulation of reverse transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900268 Any process that modulates the frequency, rate or extent of reverse transcription. GO:1900267 positive regulation of substance P receptor binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900267 activation of substance P receptor binding|up-regulation of substance P receptor binding|activation of neurokinin-1 receptor binding|up regulation of substance P receptor ligand|up-regulation of neurokinin-1 receptor binding|positive regulation of substance P receptor ligand|up regulation of substance P receptor binding|activation of substance P receptor ligand|upregulation of neurokinin-1 receptor binding|up-regulation of substance P receptor ligand|upregulation of substance P receptor binding|up regulation of neurokinin-1 receptor binding|upregulation of substance P receptor ligand|positive regulation of neurokinin-1 receptor binding Any process that activates or increases the frequency, rate or extent of substance P receptor binding. GO:1900269 negative regulation of reverse transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900269 down regulation of reverse transcription|downregulation of reverse transcription|down-regulation of reverse transcription|inhibition of reverse transcription Any process that stops, prevents or reduces the frequency, rate or extent of reverse transcription. GO:1900264 positive regulation of DNA-directed DNA polymerase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900264 up regulation of delta DNA polymerase activity|up-regulation of Tca DNA polymerase|up-regulation of sigma DNA polymerase activity|up regulation of mu DNA polymerase activity|up regulation of DNA replicase activity|upregulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|positive regulation of DNA duplicase activity|activation of alpha DNA polymerase activity|up regulation of nu DNA polymerase activity|activation of theta DNA polymerase activity|up-regulation of DNA-dependent DNA polymerase activity|up regulation of lambda DNA polymerase activity|positive regulation of Taq Pol I|activation of Klenow fragment|up regulation of DNA duplicase activity|up-regulation of DNA-directed DNA polymerase activity|upregulation of beta DNA polymerase activity|positive regulation of delta DNA polymerase activity|upregulation of kappa DNA polymerase activity|activation of DNA-directed DNA polymerase activity|upregulation of DNA nucleotidyltransferase (DNA-directed) activity|up-regulation of zeta DNA polymerase activity|upregulation of epsilon DNA polymerase activity|up-regulation of deoxyribonucleic duplicase activity|activation of duplicase|upregulation of DNA polymerase V activity|up-regulation of gamma DNA-directed DNA polymerase activity|up-regulation of DNA polymerase beta|activation of deoxyribonucleic acid duplicase activity|up-regulation of DNA polymerase III|up-regulation of DNA polymerase I|upregulation of sequenase|activation of Taq Pol I|activation of Tca DNA polymerase|up regulation of eta DNA polymerase activity|up regulation of DNA polymerase II|up-regulation of theta DNA polymerase activity|upregulation of DNA polymerase alpha|activation of delta DNA polymerase activity|up-regulation of DNA polymerase gamma|up-regulation of alpha DNA polymerase activity|up regulation of deoxyribonucleic polymerase I|up-regulation of Klenow fragment|positive regulation of eta DNA polymerase activity|up-regulation of iota DNA polymerase activity|upregulation of sigma DNA polymerase activity|positive regulation of DNA polymerase II|activation of zeta DNA polymerase activity|upregulation of Taq DNA polymerase|positive regulation of deoxyribonucleic polymerase I|up-regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|activation of gamma DNA-directed DNA polymerase activity|upregulation of DNA replicase activity|upregulation of mu DNA polymerase activity|up-regulation of duplicase|positive regulation of deoxyribonucleic acid duplicase activity|upregulation of DNA-dependent DNA polymerase activity|up-regulation of beta DNA polymerase activity|upregulation of lambda DNA polymerase activity|activation of DNA polymerase III|activation of DNA polymerase I|upregulation of nu DNA polymerase activity|positive regulation of Tca DNA polymerase|up-regulation of Taq Pol I|up-regulation of DNA nucleotidyltransferase (DNA-directed) activity|up regulation of deoxyribonucleic acid duplicase activity|upregulation of DNA duplicase activity|up regulation of kappa DNA polymerase activity|up regulation of Tca DNA polymerase|up-regulation of delta DNA polymerase activity|upregulation of DNA polymerase beta|activation of DNA polymerase gamma|upregulation of deoxyribonucleic duplicase activity|activation of eta DNA polymerase activity|activation of iota DNA polymerase activity|activation of deoxyribonucleic polymerase I|up regulation of DNA polymerase V activity|activation of DNA polymerase II|up regulation of epsilon DNA polymerase activity|positive regulation of zeta DNA polymerase activity|positive regulation of gamma DNA-directed DNA polymerase activity|up regulation of DNA-directed DNA polymerase activity|up regulation of sequenase|positive regulation of kappa DNA polymerase activity|activation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|up regulation of zeta DNA polymerase activity|positive regulation of DNA polymerase III|positive regulation of DNA polymerase I|positive regulation of epsilon DNA polymerase activity|positive regulation of DNA polymerase V activity|up-regulation of DNA polymerase alpha|upregulation of alpha DNA polymerase activity|upregulation of theta DNA polymerase activity|positive regulation of sequenase|up regulation of gamma DNA-directed DNA polymerase activity|upregulation of Klenow fragment|activation of beta DNA polymerase activity|activation of DNA nucleotidyltransferase (DNA-directed) activity|up regulation of DNA polymerase III|positive regulation of DNA polymerase gamma|up-regulation of Taq DNA polymerase|up regulation of DNA polymerase I|up regulation of sigma DNA polymerase activity|upregulation of duplicase|up-regulation of DNA replicase activity|up-regulation of eta DNA polymerase activity|positive regulation of iota DNA polymerase activity|up-regulation of mu DNA polymerase activity|up-regulation of deoxyribonucleic polymerase I|up-regulation of lambda DNA polymerase activity|up regulation of DNA-dependent DNA polymerase activity|up regulation of DNA polymerase gamma|up-regulation of nu DNA polymerase activity|up-regulation of DNA polymerase II|activation of kappa DNA polymerase activity|positive regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|upregulation of Taq Pol I|up regulation of iota DNA polymerase activity|up-regulation of DNA duplicase activity|activation of DNA polymerase V activity|activation of epsilon DNA polymerase activity|positive regulation of sigma DNA polymerase activity|upregulation of delta DNA polymerase activity|upregulation of deoxyribonucleic acid duplicase activity|positive regulation of beta DNA polymerase activity|activation of DNA polymerase alpha|activation of sequenase|up regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|positive regulation of DNA-dependent DNA polymerase activity|positive regulation of DNA nucleotidyltransferase (DNA-directed) activity|up regulation of deoxyribonucleic duplicase activity|up regulation of DNA polymerase beta|upregulation of Tca DNA polymerase|activation of Taq DNA polymerase|up regulation of beta DNA polymerase activity|up regulation of DNA nucleotidyltransferase (DNA-directed) activity|positive regulation of DNA polymerase beta|positive regulation of deoxyribonucleic duplicase activity|upregulation of DNA-directed DNA polymerase activity|activation of mu DNA polymerase activity|activation of DNA replicase activity|upregulation of zeta DNA polymerase activity|up-regulation of kappa DNA polymerase activity|activation of sigma DNA polymerase activity|up regulation of alpha DNA polymerase activity|activation of nu DNA polymerase activity|activation of lambda DNA polymerase activity|up regulation of theta DNA polymerase activity|activation of DNA-dependent DNA polymerase activity|activation of DNA duplicase activity|up regulation of Klenow fragment|up-regulation of DNA polymerase V activity|positive regulation of DNA polymerase alpha|upregulation of gamma DNA-directed DNA polymerase activity|up-regulation of epsilon DNA polymerase activity|positive regulation of alpha DNA polymerase activity|upregulation of eta DNA polymerase activity|upregulation of DNA polymerase III|up-regulation of sequenase|positive regulation of theta DNA polymerase activity|upregulation of DNA polymerase I|upregulation of DNA polymerase II|up regulation of DNA polymerase alpha|up regulation of duplicase|positive regulation of Taq DNA polymerase|positive regulation of Klenow fragment|upregulation of deoxyribonucleic polymerase I|activation of deoxyribonucleic duplicase activity|positive regulation of DNA replicase activity|upregulation of DNA polymerase gamma|activation of DNA polymerase beta|positive regulation of mu DNA polymerase activity|up regulation of Taq Pol I|positive regulation of duplicase|upregulation of iota DNA polymerase activity|positive regulation of lambda DNA polymerase activity|up-regulation of deoxyribonucleic acid duplicase activity|positive regulation of nu DNA polymerase activity|up regulation of Taq DNA polymerase Any process that activates or increases the frequency, rate or extent of DNA-directed DNA polymerase activity. GO:1900263 negative regulation of DNA-directed DNA polymerase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900263 down regulation of DNA nucleotidyltransferase (DNA-directed) activity|down-regulation of Klenow fragment|negative regulation of Klenow fragment|downregulation of Taq DNA polymerase|inhibition of DNA polymerase gamma|inhibition of sequenase|downregulation of eta DNA polymerase activity|downregulation of mu DNA polymerase activity|inhibition of iota DNA polymerase activity|downregulation of nu DNA polymerase activity|down-regulation of duplicase|negative regulation of duplicase|downregulation of DNA polymerase II|downregulation of DNA replicase activity|downregulation of lambda DNA polymerase activity|downregulation of deoxyribonucleic polymerase I|down regulation of DNA polymerase alpha|inhibition of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|inhibition of sigma DNA polymerase activity|down-regulation of Taq Pol I|negative regulation of Taq Pol I|down regulation of kappa DNA polymerase activity|inhibition of beta DNA polymerase activity|down-regulation of delta DNA polymerase activity|negative regulation of delta DNA polymerase activity|down regulation of Taq DNA polymerase|downregulation of DNA duplicase activity|down regulation of mu DNA polymerase activity|negative regulation of Tca DNA polymerase|negative regulation of deoxyribonucleic acid duplicase activity|down-regulation of deoxyribonucleic acid duplicase activity|down-regulation of Tca DNA polymerase|down regulation of epsilon DNA polymerase activity|down regulation of DNA polymerase V activity|inhibition of DNA-dependent DNA polymerase activity|inhibition of DNA nucleotidyltransferase (DNA-directed) activity|down regulation of nu DNA polymerase activity|down regulation of lambda DNA polymerase activity|down regulation of DNA replicase activity|down regulation of sequenase|inhibition of DNA polymerase beta|down-regulation of DNA-directed DNA polymerase activity|downregulation of kappa DNA polymerase activity|negative regulation of zeta DNA polymerase activity|inhibition of deoxyribonucleic duplicase activity|down regulation of DNA duplicase activity|down-regulation of zeta DNA polymerase activity|down-regulation of gamma DNA-directed DNA polymerase activity|inhibition of DNA polymerase alpha|negative regulation of gamma DNA-directed DNA polymerase activity|downregulation of DNA polymerase V activity|downregulation of epsilon DNA polymerase activity|down regulation of sigma DNA polymerase activity|inhibition of alpha DNA polymerase activity|down-regulation of DNA polymerase III|negative regulation of eta DNA polymerase activity|negative regulation of DNA polymerase I|inhibition of theta DNA polymerase activity|down-regulation of eta DNA polymerase activity|negative regulation of DNA polymerase III|down-regulation of DNA polymerase I|down-regulation of deoxyribonucleic polymerase I|down-regulation of DNA polymerase II|negative regulation of deoxyribonucleic polymerase I|inhibition of Klenow fragment|downregulation of sequenase|inhibition of Taq DNA polymerase|negative regulation of DNA polymerase II|inhibition of mu DNA polymerase activity|down regulation of DNA-dependent DNA polymerase activity|negative regulation of DNA polymerase gamma|down-regulation of DNA polymerase gamma|inhibition of DNA replicase activity|negative regulation of iota DNA polymerase activity|inhibition of lambda DNA polymerase activity|down-regulation of iota DNA polymerase activity|inhibition of nu DNA polymerase activity|downregulation of deoxyribonucleic acid duplicase activity|downregulation of sigma DNA polymerase activity|downregulation of Tca DNA polymerase|inhibition of duplicase|down regulation of DNA polymerase beta|down-regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|negative regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|inhibition of DNA duplicase activity|down regulation of deoxyribonucleic duplicase activity|inhibition of Taq Pol I|down-regulation of beta DNA polymerase activity|downregulation of DNA-dependent DNA polymerase activity|negative regulation of beta DNA polymerase activity|inhibition of delta DNA polymerase activity|down-regulation of kappa DNA polymerase activity|negative regulation of kappa DNA polymerase activity|down regulation of alpha DNA polymerase activity|downregulation of DNA-directed DNA polymerase activity|downregulation of zeta DNA polymerase activity|down regulation of theta DNA polymerase activity|downregulation of gamma DNA-directed DNA polymerase activity|down-regulation of DNA nucleotidyltransferase (DNA-directed) activity|negative regulation of DNA polymerase V activity|negative regulation of epsilon DNA polymerase activity|down regulation of Tca DNA polymerase|down-regulation of DNA polymerase V activity|down-regulation of epsilon DNA polymerase activity|down regulation of Klenow fragment|downregulation of DNA polymerase beta|down regulation of deoxyribonucleic acid duplicase activity|negative regulation of DNA nucleotidyltransferase (DNA-directed) activity|downregulation of DNA polymerase I|downregulation of DNA polymerase III|downregulation of deoxyribonucleic duplicase activity|down-regulation of sequenase|negative regulation of sequenase|down-regulation of DNA polymerase alpha|negative regulation of DNA polymerase alpha|down regulation of DNA-directed DNA polymerase activity|downregulation of DNA polymerase gamma|down regulation of zeta DNA polymerase activity|downregulation of alpha DNA polymerase activity|downregulation of theta DNA polymerase activity|down regulation of duplicase|down regulation of gamma DNA-directed DNA polymerase activity|inhibition of DNA-directed DNA polymerase activity|downregulation of iota DNA polymerase activity|down regulation of Taq Pol I|downregulation of Klenow fragment|inhibition of eta DNA polymerase activity|down regulation of delta DNA polymerase activity|down regulation of DNA polymerase III|down-regulation of sigma DNA polymerase activity|negative regulation of sigma DNA polymerase activity|down regulation of DNA polymerase I|negative regulation of Taq DNA polymerase|inhibition of DNA polymerase II|inhibition of deoxyribonucleic polymerase I|down-regulation of Taq DNA polymerase|negative regulation of mu DNA polymerase activity|down-regulation of mu DNA polymerase activity|downregulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|inhibition of Tca DNA polymerase|downregulation of beta DNA polymerase activity|inhibition of deoxyribonucleic acid duplicase activity|down-regulation of DNA-dependent DNA polymerase activity|down regulation of DNA polymerase gamma|down-regulation of lambda DNA polymerase activity|negative regulation of nu DNA polymerase activity|down-regulation of nu DNA polymerase activity|down-regulation of DNA replicase activity|downregulation of duplicase|negative regulation of DNA replicase activity|negative regulation of DNA-dependent DNA polymerase activity|negative regulation of lambda DNA polymerase activity|down regulation of iota DNA polymerase activity|downregulation of Taq Pol I|negative regulation of DNA duplicase activity|downregulation of delta DNA polymerase activity|negative regulation of DNA polymerase beta|down-regulation of DNA polymerase beta|downregulation of DNA nucleotidyltransferase (DNA-directed) activity|down-regulation of DNA duplicase activity|negative regulation of deoxyribonucleic duplicase activity|down-regulation of deoxyribonucleic duplicase activity|inhibition of zeta DNA polymerase activity|down regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|inhibition of gamma DNA-directed DNA polymerase activity|down regulation of eta DNA polymerase activity|inhibition of kappa DNA polymerase activity|down regulation of beta DNA polymerase activity|negative regulation of theta DNA polymerase activity|inhibition of DNA polymerase III|down-regulation of alpha DNA polymerase activity|down regulation of DNA polymerase II|inhibition of DNA polymerase V activity|negative regulation of alpha DNA polymerase activity|inhibition of DNA polymerase I|down regulation of deoxyribonucleic polymerase I|inhibition of epsilon DNA polymerase activity|downregulation of DNA polymerase alpha|down-regulation of theta DNA polymerase activity Any process that stops, prevents or reduces the frequency, rate or extent of DNA-directed DNA polymerase activity. GO:1900266 negative regulation of substance P receptor binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900266 down regulation of substance P receptor ligand|down-regulation of neurokinin-1 receptor binding|negative regulation of neurokinin-1 receptor binding|downregulation of substance P receptor ligand|down-regulation of substance P receptor binding|inhibition of neurokinin-1 receptor binding|negative regulation of substance P receptor ligand|down-regulation of substance P receptor ligand|downregulation of substance P receptor binding|down regulation of substance P receptor binding|down regulation of neurokinin-1 receptor binding|inhibition of substance P receptor binding|downregulation of neurokinin-1 receptor binding|inhibition of substance P receptor ligand Any process that stops, prevents or reduces the frequency, rate or extent of substance P receptor binding. GO:0046199 cresol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046199 cresol degradation|cresol breakdown|cresol catabolism The chemical reactions and pathways resulting in the breakdown of cresol, a mixture of the aromatic alcohol isoforms o-, p-, and m-cresol, which is obtained from coal tar or petroleum. The isomers are used as disinfectants, textile scouring agents, surfactants and as intermediates in the manufacture of salicylaldehyde, coumarin, and herbicides as well as being a major component of creosote. GO:1900265 regulation of substance P receptor binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900265 regulation of substance P receptor ligand|regulation of neurokinin-1 receptor binding Any process that modulates the frequency, rate or extent of substance P receptor binding. GO:1900271 regulation of long-term synaptic potentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900271 regulation of LTP|regulation of long-term potentiation Any process that modulates the frequency, rate or extent of long-term synaptic potentiation. GO:1900270 positive regulation of reverse transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900270 up-regulation of reverse transcription|upregulation of reverse transcription|up regulation of reverse transcription|activation of reverse transcription Any process that activates or increases the frequency, rate or extent of reverse transcription. GO:1900273 positive regulation of long-term synaptic potentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900273 positive regulation of long-term potentiation|up regulation of long-term potentiation|up regulation of long-term synaptic potentiation|activation of long-term synaptic potentiation|up regulation of LTP|positive regulation of LTP|upregulation of long-term potentiation|activation of LTP|up-regulation of long-term synaptic potentiation|up-regulation of long-term potentiation|up-regulation of LTP|upregulation of long-term synaptic potentiation|activation of long-term potentiation|upregulation of LTP Any process that activates or increases the frequency, rate or extent of long-term synaptic potentiation. GO:1900272 negative regulation of long-term synaptic potentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900272 downregulation of long-term synaptic potentiation|down regulation of LTP|downregulation of long-term potentiation|downregulation of LTP|down-regulation of long-term synaptic potentiation|down regulation of long-term potentiation|negative regulation of LTP|down-regulation of LTP|inhibition of long-term potentiation|inhibition of long-term synaptic potentiation|inhibition of LTP|negative regulation of long-term potentiation|down regulation of long-term synaptic potentiation|down-regulation of long-term potentiation Any process that stops, prevents or reduces the frequency, rate or extent of long-term synaptic potentiation. GO:0071139 resolution of recombination intermediates biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071139 The cleavage and rejoining of intermediates, such as Holliday junctions, formed during DNA recombination to produce two intact molecules in which genetic material has been exchanged. GO:0071138 alpha5-beta5-fibronectin-SFRP2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071138 ITGA5-ITGB5-FN-1-SFRP2 complex A protein complex that consists of an alpha5-beta5 integrin complex bound to fibronectin and secreted frizzled-related protein 2. GO:0071137 alphaV-beta3 integrin-CD98 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071137 ITGAV-ITGB3-SLC3A2 complex A protein complex that consists of an alphaV-beta3 integrin complex bound to the cell surface antigen CD98. GO:0071136 alpha7-beta1 integrin-laminin alpha-2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071136 ITGA7-ITGB1-LAMA2 complex A protein complex that consists of an alpha7-beta1 integrin complex bound to laminin alpha-2. GO:0071135 alpha7-beta1 integrin-focal adhesion kinase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071135 ITGA7-ITGB1-PTK2 complex A protein complex that consists of an alpha7-beta1 integrin complex bound to focal adhesion kinase. GO:0071134 alpha9-beta1 integrin-thrombospondin-1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071134 ITGA9-ITGB1-THBS1 complex A protein complex that consists of an alpha9-beta1 integrin complex bound to thrombospondin-1. GO:0071133 alpha9-beta1 integrin-ADAM8 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071133 ITGA9-ITGB1-ADAM8 complex A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM8. GO:0071165 GINS complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071165 The aggregation, arrangement and bonding together of a set of components to form a GINS complex, a heterotetrameric protein complex that associates with DNA replication origins and replication forks. GO:0071164 RNA trimethylguanosine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071164 snRNA methyltransferase activity|cap hypermethylase activity|small nuclear RNA methyltransferase activity Catalysis of two successive methyl transfer reactions from AdoMet to the N-2 atom of guanosine, thereby converting 7-methylguanosine in an RNA cap to 2,2,7 trimethylguanosine. GO:0071163 DNA replication preinitiation complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071163 pre-IC complex assembly|DNA replication preinitiation complex formation The aggregation, arrangement and bonding together of a set of components to form the DNA replication preinitiation complex, a protein-DNA complex that is assembled at DNA replication origins immediately prior to the initiation of DNA replication. The complex consists of proteins that initiate the DNA binding, melt the helix and enable helicase activity. GO:0071162 CMG complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071162 unwindosome A protein complex that contains the GINS complex, Cdc45p, and the heterohexameric MCM complex, and that is involved in unwinding DNA during replication. GO:0071161 cyanophycin synthetase activity (L-arginine-adding) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071161 RHEA:23888|EC:6.3.2.30 Catalysis of the reaction: ATP + [L-Asp(4-L-Arg)]n-L-Asp + L-arginine = ADP + phosphate + [L-Asp(4-L-Arg)]n+1. GO:0071160 cyanophycin synthetase activity (L-aspartate-adding) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071160 EC:6.3.2.29|RHEA:13277 Catalysis of the reaction: ATP + [L-Asp(4-L-Arg)]n + L-Asp = ADP + phosphate + [L-Asp(4-L-Arg)]n-L-Asp. GO:1900279 regulation of CD4-positive, alpha-beta T cell costimulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900279 regulation of CD4-positive, alpha beta T cell costimulation Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell costimulation. GO:1900278 positive regulation of proteinase activated receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900278 up regulation of proteinase activated receptor activity|upregulation of proteinase activated receptor activity|up-regulation of proteinase activated receptor activity|activation of proteinase activated receptor activity Any process that activates or increases the frequency, rate or extent of proteinase activated receptor activity. GO:1900275 negative regulation of phospholipase C activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900275 down regulation of lipophosphodiesterase C|negative regulation of phosphatidase C|down-regulation of phosphatidase C|down-regulation of phospholipase C activity|downregulation of lipophosphodiesterase C|down-regulation of lecithinase C activity|negative regulation of lecithinase C activity|downregulation of phospholipase C activity|inhibition of phosphatidase C|down-regulation of lipophosphodiesterase C|negative regulation of lipophosphodiesterase C|down regulation of phospholipase C activity|inhibition of phospholipase C activity|downregulation of lecithinase C activity|down regulation of phosphatidase C|down regulation of lecithinase C activity|downregulation of phosphatidase C|inhibition of lipophosphodiesterase C|inhibition of lecithinase C activity Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase C activity. GO:1900274 regulation of phospholipase C activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900274 regulation of lipophosphodiesterase C|regulation of lecithinase C activity|regulation of phosphatidase C Any process that modulates the frequency, rate or extent of phospholipase C activity. GO:1900277 negative regulation of proteinase activated receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900277 down-regulation of proteinase activated receptor activity|downregulation of proteinase activated receptor activity|down regulation of proteinase activated receptor activity|inhibition of proteinase activated receptor activity Any process that stops, prevents or reduces the frequency, rate or extent of proteinase activated receptor activity. GO:1900276 regulation of proteinase activated receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900276 Any process that modulates the frequency, rate or extent of proteinase activated receptor activity. GO:1900282 regulation of cellobiose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900282 regulation of cellobiose catabolism Any process that modulates the frequency, rate or extent of cellobiose catabolic process. GO:1900281 positive regulation of CD4-positive, alpha-beta T cell costimulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900281 up-regulation of CD4-positive, alpha beta T cell costimulation|positive regulation of CD4-positive, alpha beta T cell costimulation|upregulation of CD4-positive, alpha beta T cell costimulation|up regulation of CD4-positive, alpha beta T cell costimulation|activation of CD4-positive, alpha beta T cell costimulation Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell costimulation. GO:1900284 positive regulation of cellobiose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900284 up regulation of cellobiose catabolic process|up-regulation of cellobiose catabolism|upregulation of cellobiose catabolic process|upregulation of cellobiose catabolism|up-regulation of cellobiose catabolic process|activation of cellobiose catabolic process|up regulation of cellobiose catabolism|activation of cellobiose catabolism|positive regulation of cellobiose catabolism Any process that activates or increases the frequency, rate or extent of cellobiose catabolic process. GO:1900283 negative regulation of cellobiose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900283 downregulation of cellobiose catabolic process|inhibition of cellobiose catabolism|down regulation of cellobiose catabolic process|inhibition of cellobiose catabolic process|down regulation of cellobiose catabolism|downregulation of cellobiose catabolism|down-regulation of cellobiose catabolic process|negative regulation of cellobiose catabolism|down-regulation of cellobiose catabolism Any process that stops, prevents or reduces the frequency, rate or extent of cellobiose catabolic process. GO:1900280 negative regulation of CD4-positive, alpha-beta T cell costimulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900280 inhibition of CD4-positive, alpha beta T cell costimulation|negative regulation of CD4-positive, alpha beta T cell costimulation|down regulation of CD4-positive, alpha beta T cell costimulation|downregulation of CD4-positive, alpha beta T cell costimulation|down-regulation of CD4-positive, alpha beta T cell costimulation Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell costimulation. GO:0071169 establishment of protein localization to chromatin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071169 establishment of protein localisation to chromatin The directed movement of a protein to a part of a chromosome that is organized into chromatin. GO:0071168 protein localization to chromatin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071168 protein localisation to chromatin Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into chromatin. GO:0071167 obsolete ribonucleoprotein complex import into nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071167 RNP import into nucleus|ribonucleoprotein complex nucleus import|ribonucleoprotein complex transport from cytoplasm to nucleus|ribonucleoprotein import into nucleus|ribonucleoprotein complex targeting to nucleus|ribonucleoprotein complex import into cell nucleus OBSOLETE. The directed movement of a ribonucleoprotein complex from the cytoplasm to the nucleus. GO:0071166 ribonucleoprotein complex localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071166 cellular ribonucleoprotein complex localization|establishment and maintenance of ribonucleoprotein complex localization|ribonucleoprotein complex localisation|RNP localization Any process in which a ribonucleoprotein complex is transported to, or maintained in, a specific location within a cell. GO:0071154 G-protein alpha(i)1-synembrin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071154 Ric-8A G(i) alpha-2 subunit complex|Ric-8A G(i) alpha-1 subunit complex A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(i)1 subunit of a heterotrimeric G protein. GO:0071153 G-protein alpha(o)-synembrin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071153 Ric-8A G(o) alpha-1 subunit complex|Ric-8A G(o) alpha-2 subunit complex A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(o) subunit of a heterotrimeric G protein. GO:0071152 G-protein alpha(q)-synembrin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071152 Ric-8A G(q) alpha subunit complex A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(q) subunit of a heterotrimeric G protein. GO:0071151 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0071151 GO:0071150 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0071150 UBERON:0036066 inferior endocardial cushion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036066 ventral endocardial cushion The endocardial cushion that forms on the ventral surface of the AV canal. GO:1900289 negative regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900289 inhibition of coenzyme F420-dependent bicyclic nitroimidazole catabolic process|inhibition of coenzyme F420-dependent nitroimidazole catabolism|down regulation of coenzyme F420-dependent nitroreductase activity|downregulation of coenzyme F420-dependent nitroreductase activity|downregulation of coenzyme F420-dependent nitroimidazole breakdown|down regulation of coenzyme F420-dependent nitroimidazole breakdown|negative regulation of coenzyme F420-dependent nitroimidazole reduction|down-regulation of coenzyme F420-dependent nitroimidazole reduction|inhibition of coenzyme F420-dependent nitroimidazole breakdown|down regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process|negative regulation of coenzyme F420-dependent nitroreductase activity|down regulation of coenzyme F420-dependent nitroimidazole catabolism|down-regulation of coenzyme F420-dependent nitroreductase activity|downregulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process|downregulation of coenzyme F420-dependent nitroimidazole catabolism|downregulation of coenzyme F420-dependent nitroimidazole reduction|down regulation of coenzyme F420-dependent nitroimidazole reduction|down-regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process|inhibition of coenzyme F420-dependent nitroimidazole reduction|inhibition of coenzyme F420-dependent nitroreductase activity|down-regulation of coenzyme F420-dependent nitroimidazole catabolism|negative regulation of coenzyme F420-dependent nitroimidazole catabolism|negative regulation of coenzyme F420-dependent nitroimidazole breakdown|down-regulation of coenzyme F420-dependent nitroimidazole breakdown Any process that stops, prevents or reduces the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process. UBERON:0036067 superior endocardial cushion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036067 dorsal endocardial cushion The endocardial cushion that forms on the dorsal surface of the AV canal. UBERON:0036069 tracheoesophageal fold biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036069 esophagotracheal fold One of two longitudinal ridges that develop caudal to the pharynx and fuses to give rise to the tracheoesophageal septum. GO:1900286 negative regulation of cellotriose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900286 down regulation of cellotriose transport|downregulation of cellotriose transport|down-regulation of cellotriose transport|inhibition of cellotriose transport Any process that stops, prevents or reduces the frequency, rate or extent of cellotriose transport. GO:1900285 regulation of cellotriose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900285 Any process that modulates the frequency, rate or extent of cellotriose transport. GO:1900288 regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900288 regulation of coenzyme F420-dependent nitroreductase activity|regulation of coenzyme F420-dependent nitroimidazole breakdown|regulation of coenzyme F420-dependent nitroimidazole catabolism|regulation of coenzyme F420-dependent nitroimidazole reduction Any process that modulates the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process. GO:1900287 positive regulation of cellotriose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900287 upregulation of cellotriose transport|up regulation of cellotriose transport|activation of cellotriose transport|up-regulation of cellotriose transport Any process that activates or increases the frequency, rate or extent of cellotriose transport. GO:1900293 positive regulation of galactotriose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900293 up-regulation of galactotriose transport|upregulation of galactotriose transport|up regulation of galactotriose transport|activation of galactotriose transport Any process that activates or increases the frequency, rate or extent of galactotriose transport. GO:1900292 negative regulation of galactotriose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900292 down-regulation of galactotriose transport|inhibition of galactotriose transport|down regulation of galactotriose transport|downregulation of galactotriose transport Any process that stops, prevents or reduces the frequency, rate or extent of galactotriose transport. GO:1900295 negative regulation of heptasaccharide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900295 down-regulation of heptasaccharide transport|inhibition of heptasaccharide transport|down regulation of heptasaccharide transport|downregulation of heptasaccharide transport Any process that stops, prevents or reduces the frequency, rate or extent of heptasaccharide transport. GO:1900294 regulation of heptasaccharide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900294 Any process that modulates the frequency, rate or extent of heptasaccharide transport. GO:1900291 regulation of galactotriose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900291 Any process that modulates the frequency, rate or extent of galactotriose transport. GO:1900290 positive regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900290 up-regulation of coenzyme F420-dependent nitroreductase activity|up regulation of coenzyme F420-dependent nitroimidazole catabolism|activation of coenzyme F420-dependent nitroimidazole catabolism|up-regulation of coenzyme F420-dependent nitroimidazole breakdown|activation of coenzyme F420-dependent nitroimidazole breakdown|positive regulation of coenzyme F420-dependent nitroimidazole catabolism|upregulation of coenzyme F420-dependent nitroimidazole reduction|upregulation of coenzyme F420-dependent nitroreductase activity|up-regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process|positive regulation of coenzyme F420-dependent nitroimidazole breakdown|up-regulation of coenzyme F420-dependent nitroimidazole catabolism|up regulation of coenzyme F420-dependent nitroimidazole breakdown|activation of coenzyme F420-dependent nitroimidazole reduction|up-regulation of coenzyme F420-dependent nitroimidazole reduction|up regulation of coenzyme F420-dependent nitroreductase activity|upregulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process|positive regulation of coenzyme F420-dependent nitroreductase activity|upregulation of coenzyme F420-dependent nitroimidazole catabolism|upregulation of coenzyme F420-dependent nitroimidazole breakdown|activation of coenzyme F420-dependent nitroreductase activity|positive regulation of coenzyme F420-dependent nitroimidazole reduction|up regulation of coenzyme F420-dependent nitroimidazole reduction|up regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process|activation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process Any process that activates or increases the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process. GO:0071159 NF-kappaB complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071159 A protein complex that consists of a homo- or heterodimer of members of a family of structurally related proteins that contain a conserved N-terminal region called the Rel homology domain (RHD). In the nucleus, NF-kappaB complexes act as transcription factors. In unstimulated cells, NF-kappaB dimers are sequestered in the cytoplasm by IkappaB monomers; signals that induce NF-kappaB activity cause degradation of IkappaB, allowing NF-kappaB dimers to translocate to the nucleus and induce gene expression. GO:0071158 positive regulation of cell cycle arrest biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071158 Any process that increases the rate, frequency, or extent of cell cycle arrest, the process in which the cell cycle is halted during one of the normal phases. GO:0071157 negative regulation of cell cycle arrest biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071157 Any process that decreases the rate, frequency, or extent of cell cycle arrest, the process in which the cell cycle is halted during one of the normal phases. GO:0071156 regulation of cell cycle arrest biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071156 Any process that modulates the rate, frequency, or extent of cell cycle arrest, the process in which the cell cycle is halted during one of the normal phases. GO:0071155 G-protein alpha(13)-synembrin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071155 Ric-8A G alpha 13 subunit complex A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(13) subunit of a heterotrimeric G protein. GO:0071187 protocadherin-alpha-v4-protocadherin-gamma-b4 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071187 Pcdhga1-Pcdhgb4 complex A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-b4, and is involved in the regulation of protein localization to the plasma membrane. GO:0071186 protocadherin-alpha-v4-protocadherin-gamma-b2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071186 Pcdhga1-Pcdhgb2 complex A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-b2, and is involved in the regulation of protein localization to the plasma membrane. UBERON:0036070 tracheoesophageal septum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036070 tracheoesophageal ridges|esophagotracheal septum The tracheoesophageal septum is formed from the tracheoesophageal folds which fuse in the midline to form a structure called tracheoesophageal septum. It divides the esophagus from the trachea. It divides the foregut tube into the laryngotracheal tube ventrally and esophagus dorsally. Developmental abnormalities can lead to a tracheoesophageal fistula. GO:0071185 protocadherin-alpha-v4-protocadherin-gamma-a3 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071185 Pcdhga1-Pcdhga3 complex A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-a3, and is involved in the regulation of protein localization to the plasma membrane. UBERON:0036073 respiratory primordium mesenchyme biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036073 respiratory primordium associated mesenchyme CHEBI:142590 3-aminoisobutanoic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142590 GO:0071184 protocadherin-alpha-v4-protocadherin-gamma-a1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071184 Pcdhga1-Pcdha4 complex A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-a1, and is involved in the regulation of protein localization to the plasma membrane. UBERON:0036072 respiratory primordium epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036072 GO:0071183 protocadherin-alpha-protocadherin-gamma complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071183 A protein complex that contains two cell adhesion molecules, a protocadherin-alpha and a protocadherin-gamma, and is involved in the regulation of protein localization to the plasma membrane. GO:0071182 MAML3-RBP-Jkappa-ICN4 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071182 MAML3-RBP-Jkappa-Notch4 complex A protein complex that consists of the intracellular domain of Notch4 (ICN4), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling. GO:0071181 MAML3-RBP-Jkappa-ICN3 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071181 MAML3-RBP-Jkappa-Notch3 complex A protein complex that consists of the intracellular domain of Notch3 (ICN3), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling. GO:0071180 MAML3-RBP-Jkappa-ICN2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071180 MAML3-RBP-Jkappa-Notch2 complex A protein complex that consists of the intracellular domain of Notch2 (ICN2), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling. GO:1900297 regulation of hexasaccharide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900297 Any process that modulates the frequency, rate or extent of hexasaccharide transport. GO:1900296 positive regulation of heptasaccharide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900296 up regulation of heptasaccharide transport|activation of heptasaccharide transport|up-regulation of heptasaccharide transport|upregulation of heptasaccharide transport Any process that activates or increases the frequency, rate or extent of heptasaccharide transport. GO:1900299 positive regulation of hexasaccharide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900299 up-regulation of hexasaccharide transport|activation of hexasaccharide transport|up regulation of hexasaccharide transport|upregulation of hexasaccharide transport Any process that activates or increases the frequency, rate or extent of hexasaccharide transport. CHEBI:142594 alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[alpha-N-acetylneuraminosyl-(2->6)]-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142594 GO:1900298 negative regulation of hexasaccharide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900298 down-regulation of hexasaccharide transport|downregulation of hexasaccharide transport|down regulation of hexasaccharide transport|inhibition of hexasaccharide transport Any process that stops, prevents or reduces the frequency, rate or extent of hexasaccharide transport. GO:0071189 protocadherin-alpha-v7-protocadherin-gamma-a3 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071189 Pcdha7-Pcdhga3 complex A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-a3, and is involved in the regulation of protein localization to the plasma membrane. GO:0071188 protocadherin-alpha-v7-protocadherin-gamma-a1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071188 Pcdha7-Pcdhga1 complex A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-a1, and is involved in the regulation of protein localization to the plasma membrane. GO:0071176 MAML2-RBP-Jkappa-ICN2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071176 MAML2-RBP-Jkappa-Notch2 complex A protein complex that consists of the intracellular domain of Notch2 (ICN2), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling. GO:0071175 MAML2-RBP-Jkappa-ICN1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071175 MAML2-RBP-Jkappa-Notch1 complex A protein complex that consists of the intracellular domain of Notch1 (ICN1), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling. GO:0071174 mitotic spindle checkpoint biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0071174 topoisomerase II checkpoint|topo II checkpoint|mitotic cell cycle spindle checkpoint A mitotic cell cycle checkpoint that originates from the spindle and delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and oriented, the completion of anaphase until chromosomes are attached to the spindle, or mitotic exit and cytokinesis when the spindle does not form. GO:0071173 spindle assembly checkpoint biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0071173 SAC A cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and chromosomes are attached to the spindle. GO:0071172 dihydromonapterin reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071172 Catalysis of the reaction: 7,8-dihydromonapterin + NADPH = tetrahydromonapterin + NADP+. GO:0071171 site-specific DNA replication termination at RTS1 barrier biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071171 A DNA replication termination process that takes place at the RTS1 termination site in the mating type locus, in a specific direction required for subsequent imprinting and mating-type switching. GO:0071170 site-specific DNA replication termination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071170 A DNA replication termination process that takes place at a specific termination site. CHEBI:142587 N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142587 CHEBI:142582 alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142582 GO:0071179 MAML3-RBP-Jkappa-ICN1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071179 MAML3-RBP-Jkappa-Notch1 complex A protein complex that consists of the intracellular domain of Notch1 (ICN1), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling. GO:0071178 MAML2-RBP-Jkappa-ICN4 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071178 MAML2-RBP-Jkappa-Notch4 complex A protein complex that consists of the intracellular domain of Notch4 (ICN4), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling. GO:0071177 MAML2-RBP-Jkappa-ICN3 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071177 MAML2-RBP-Jkappa-Notch3 complex A protein complex that consists of the intracellular domain of Notch3 (ICN3), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling. SO:0001410 experimental_feature biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0001410 analysis feature|experimental_output_artefact|experimental output artefact A region which is the result of some arbitrary experimental procedure. The procedure may be carried out with biological material or inside a computer. CHEBI:35418 N-acetylneuraminate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35418 CHEBI:35417 alpha-amino-acid residue radical biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35417 CHEBI:11449 2,5-didehydro-D-gluconate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_11449 CHEBI:35410 primary diamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35410 CHEBI:84387 (1s,4s)-prephenic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84387 GO:0061720 6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061720 The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and 3-sulfolactaldehyde (SLA). CHEBI:35412 aminal biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35412 CHEBI:35411 alkane-alpha,omega-diamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35411 GO:0061722 sulphoglycolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061722 sulfoglycolysis The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and pyruvate. CHEBI:35414 N-monoacetylalkane-alpha,omega-diamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35414 GO:0061721 6-sulfoquinovose(1-) catabolic process to 3-sulfopropanediol(1-) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061721 MetaCyc:PWY-7446 The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and 3-sulfopropanediol(1-). CHEBI:35416 alpha-amino-acid residue anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35416 GO:0061724 lipophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061724 The selective autophagy process in which lipid droplets are delivered to the vacuole and degraded in response to changing cellular conditions. GO:0061723 glycophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061723 The selective autophagy process in which cellular glycogen is delivered to the vacuole and degraded in response to changing cellular conditions. CHEBI:35415 alpha-amino-acid residue cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35415 GO:0061726 mitochondrion disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061726 mitochondrion degradation The disaggregation of a mitochondrion into its constituent components. GO:0061725 cytosolic lipolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061725 The chemical reactions and pathways resulting in the breakdown of lipid droplets and hydrolysis of stored triglycerides occurring through the orchestrated activation of cytosolic lipases. GO:0061728 GDP-mannose biosynthetic process from mannose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061728 The chemical reactions and pathways resulting in the formation of GDP-mannose from mannose. GO:0061727 methylglyoxal catabolic process to lactate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061727 The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into lactate. GO:0061729 GDP-mannose biosynthetic process from fructose-6-phosphate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061729 Reactome:R-HSA-446205 The chemical reactions and pathways resulting in the formation of GDP-mannose from fructose-6-phosphate. CHEBI:35428 ortho-fused bicyclic hydrocarbon biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35428 CHEBI:11438 2,4-dichloro-cis,cis-muconate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_11438 CHEBI:84399 1,1',2-trilinoleoyl-2'-oleoyl cardiolipin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84399 CHEBI:35421 lithocholic acid sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35421 CHEBI:35420 pregnenolone sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35420 CHEBI:84398 tetralinoleoyl cardiolipin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84398 CHEBI:35423 L-arabinose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35423 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061711 RHEA:37059|Reactome:R-HSA-6784494|EC:2.3.1.234|MetaCyc:RXN-14570 Catalysis of the reaction: L-threonylcarbamoyladenylate + adenine(37) in tRNA = AMP + N(6)-L-threonylcarbamoyladenine(37) in tRNA. CHEBI:35425 D-ribose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35425 GO:0061710 L-threonylcarbamoyladenylate synthase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061710 RHEA:36407|EC:2.7.7.87|MetaCyc:RXN-14569 Catalysis of the reaction: L-threonine + ATP + bicarbonate = L-threonylcarbamoyladenylate + diphosphate + H(2)O. GO:0061713 anterior neural tube closure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061713 The step in the formation of the neural tube, where the paired anterior neural folds are brought together and fuse at the dorsal midline. CHEBI:35427 ortho-fused polycyclic hydrocarbon biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35427 GO:0061712 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061712 EC:2.8.4.5|RHEA:37075|MetaCyc:RXN-14531 Catalysis of the reaction: N(6)-L-threonylcarbamoyladenine(37) in tRNA + sulfur-(sulfur carrier) + 2 S-adenosyl-L-methionine = 2-methylthio-N(6)-L-threonylcarbamoyladenine(37) in tRNA + S-adenosyl-L-homocysteine + (sulfur carrier) + L-methionine + 5'-deoxyadenosine. CHEBI:35426 ortho-fused bicyclic arene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35426 GO:0061715 miRNA 2'-O-methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061715 The posttranscriptional addition of a methyl group to the 2' oxygen atom of a nucleotide residue in an miRNA molecule. GO:0061714 folic acid receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061714 folate receptor activity Combining selectively with extracellular folic acid and delivering it into the cell via endocytosis. GO:0061717 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0061717 GO:0061716 miRNA export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061716 The directed movement of a processed miRNA from the nucleus to the cytoplasm. GO:0061719 glucose catabolic process to pyruvate utilizing ADP biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061719 MetaCyc:P341-PWY The chemical reactions and pathways resulting in the breakdown of glucose into pyruvate, with the concomitant production of a small amount of ATP and the utilization of ADP in the initial kinase reactions. GO:0061718 glucose catabolic process to pyruvate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061718 glucose catabolism to pyruvate The chemical reactions and pathways resulting in the breakdown of glucose, with the production of pyruvate. GO:0046107 uracil biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046107 uracil anabolism|uracil synthesis|uracil formation|uracil biosynthesis The chemical reactions and pathways resulting in the formation of uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA. GO:0046106 thymine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046106 thymine biosynthesis|thymine anabolism|thymine synthesis|thymine formation The chemical reactions and pathways resulting in the formation of thymine, 5-methyluracil, one of the two major pyrimidine bases present (as thymidine) in DNA but not found in RNA other than (as ribothymidine) in transfer RNA, where it is a minor base. GO:0046105 thymidine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046105 deoxyribosylthymine biosynthetic process|deoxyribosylthymine biosynthesis|thymidine anabolism|thymidine synthesis|thymidine biosynthesis|thymidine formation The chemical reactions and pathways resulting in the formation of thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA. GO:0046104 thymidine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046104 deoxyribosylthymine metabolism|thymidine metabolism|deoxyribosylthymine metabolic process The chemical reactions and pathways involving thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA. GO:0046103 inosine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046103 inosine biosynthesis|inosine anabolism|inosine synthesis|inosine formation The chemical reactions and pathways resulting in the formation of inosine, hypoxanthine riboside, a nucleoside found free but not in combination in nucleic acids except in the anticodons of some tRNAs. GO:0046102 inosine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046102 inosine metabolism The chemical reactions and pathways involving inosine, hypoxanthine riboside, a nucleoside found free but not in combination in nucleic acids except in the anticodons of some tRNAs. GO:0046101 hypoxanthine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046101 hypoxanthine biosynthesis|hypoxanthine anabolism|hypoxanthine synthesis|hypoxanthine formation The chemical reactions and pathways resulting in the formation of hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. Its ribonucleoside is known as inosine and its ribonucleotide as inosinate. GO:0046100 hypoxanthine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046100 hypoxanthine metabolism The chemical reactions and pathways involving hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. Its ribonucleoside is known as inosine and its ribonucleotide as inosinate. GO:0061740 protein targeting to lysosome involved in chaperone-mediated autophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061740 The targeting of a protein to the lysosome process in which an input protein binds to a chaperone and subsequently to a lysosomal receptor. GO:0061742 chaperone-mediated autophagy translocation complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061742 chaperone-mediated autophagy receptor complex|CMA translocation complex|CMA receptor complex A lysosomal membrane protein complex that enables the translocation of a target protein across the lysosomal membrane as part of chaperone-mediated autophagy. GO:0061741 chaperone-mediated protein transport involved in chaperone-mediated autophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061741 The chaperone-mediated protein transport process in which a protein that is bound to a chaperone and a lysosomal receptor is unfolded and transported into the lysosome as part of chaperone-mediated autophagy. GO:0061744 motor behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061744 The specific neuromuscular movement of a single organism in response to external or internal stimuli. GO:0061743 motor learning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061743 Any process in which an organism acquires a novel neuromuscular action or movement as the result of experience. GO:0061746 obsolete single-stranded DNA-dependent GTPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061746 OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate; this reaction requires the presence of single-stranded DNA, and it drives another reaction. GO:0046109 uridine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046109 uridine biosynthesis|uridine anabolism|uridine synthesis|uridine formation The chemical reactions and pathways resulting in the formation of uridine, uracil riboside, a ribonucleoside very widely distributed but occurring almost entirely as phosphoric esters in ribonucleotides and ribonucleic acids. GO:0061745 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0061745 GO:0046108 uridine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046108 uridine metabolism The chemical reactions and pathways involving uridine, uracil riboside, a ribonucleoside very widely distributed but occurring almost entirely as phosphoric esters in ribonucleotides and ribonucleic acids. GO:0061748 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0061748 GO:0061747 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0061747 GO:0061749 forked DNA-dependent helicase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061749 Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA helix containing forked DNA. GO:0046110 xanthine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046110 xanthine metabolism The chemical reactions and pathways involving xanthine, 2,6-dihydroxypurine, a purine formed in the metabolic breakdown of guanine but not present in nucleic acids. GO:0046118 7-methylguanosine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046118 7-methylguanosine anabolism|7-methylguanosine synthesis|7-methylguanosine biosynthesis|7-methylguanosine formation The chemical reactions and pathways resulting in the formation of 7-methylguanosine, a modified nucleoside that forms a cap at the 5'-terminus of eukaryotic mRNA. GO:0046117 queuosine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046117 queuosine degradation|queuosine breakdown|queuosine catabolism The chemical reactions and pathways resulting in the breakdown of queuosines, any of a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents. CHEBI:35406 oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35406 GO:0046116 queuosine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046116 queuosine metabolism The chemical reactions and pathways involving queuosines, any of a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents. GO:0046115 guanosine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046115 guanosine phosphorolysis|guanosine catabolism|guanosine degradation|guanosine breakdown The chemical reactions and pathways resulting in the breakdown of guanine, guanine riboside, a nucleoside with a wide species distribution. GO:0046114 guanosine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046114 guanosine synthesis|guanosine formation|guanosine biosynthesis|guanosine anabolism The chemical reactions and pathways resulting in the formation of guanine, guanine riboside, a nucleoside with a wide species distribution. GO:0046113 nucleobase catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046113 nucleobase degradation|nucleobase breakdown|nucleobase catabolism The chemical reactions and pathways resulting in the breakdown of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid. GO:0046112 nucleobase biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046112 nucleobase anabolism|nucleobase biosynthesis|nucleobase synthesis|nucleobase formation The chemical reactions and pathways resulting in the formation of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid. GO:0046111 xanthine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046111 xanthine biosynthesis|xanthine anabolism|xanthine synthesis|xanthine formation The chemical reactions and pathways resulting in the formation of xanthine, 2,6-dihydroxypurine, a purine formed in the metabolic breakdown of guanine but not present in nucleic acids. GO:0061731 ribonucleoside-diphosphate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061731 ribonucleoside 5'-diphosphate reductase activity|ribonucleotide diphosphate reductase activity|purine/pyrimidine nucleoside diphosphate reduction|nucleoside diphosphate reductase activity|class II ribonucleotide reductase activity|class I ribonucleotide reductase activity|class III ribonucleotide reductase activity|adenosylcobalamin-dependent ribonucleotide reductase activity|aerobic non-heme iron-dependent ribonucleotide reductase activity|anaerobic iron-sulfur-dependent ribonucleotide reductase activity|class II ribonucleoside-diphosphate reductase activity|ribonucleotide reductase activity|RNR Catalysis of the formation of 2'-deoxyribonucleoside diphosphate from ribonucleoside diphosphate, using either thioredoxin disulfide or glutaredoxin disulfide as an acceptor. CHEBI:35401 chromium oxoacid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35401 UBERON:0002691 ventral tegmental area biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002691 ventromedial mesencephalic tegmentum|area tegmentalis ventralis|a10a|ventral tegmental nucleus (tsai)|VTA|ventral tegmental area of tsai|ventral tegmental area (Tsai)|area tegmentalis ventralis (Tsai)|tegmentum ventrale|ventral tegmental nucleus of tsai|ventral tegmental nucleus (Rioch)|ventral brain stem Unpaired midbrain region situated in the ventromedial portion of the reticular formation. The VTA is medial to the substantia nigra and ventral to the red nucleus, and extends caudally from the posterior hypothalamus in the diencephalon. The VTA contains dopamine neurons that project to various limbic and cortical areas and is a critical component of the brain's reward circuitry. GO:0061730 C-rich strand telomeric DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061730 Interacting selectively and non-covalently with C-rich, single-stranded, telomere-associated DNA. CHEBI:35400 meso-tartrate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35400 GO:0061733 peptide-lysine-N-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061733 Reactome:R-HSA-6811508|Reactome:R-HSA-9626945|Reactome:R-HSA-8951966|Reactome:R-HSA-9617758|Reactome:R-HSA-9620515 Catalysis of the reaction: acetyl-CoA + lysine in peptide = CoA + N-acetyl-lysine-peptide. PR:000011459 neurotrophin-3 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000011459 NT-3|neurotrophic factor|nerve growth factor 2|Ntf-3|HDNF|NTF3|NGF-2 A neurotrophin that is a translation product of the human NTF3 gene or a 1:1 ortholog thereof. CHEBI:35403 chromium coordination entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35403 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061732 Reactome:R-HSA-372342.1|Reactome:R-HSA-71397.1 The chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate in the mitochondrion. The process begins with the transport of pyruvate from the cytosol to the mitochondrion where it is subsequently decarboxylated to form acetyl-CoA. CHEBI:35402 chromium oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35402 GO:0061735 DNM1L-mediated stimulation of mitophagy in response to mitochondrial depolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061735 dynamin-like protein-mediated stimulation of mitophagy in response to mitochondrial depolarization A positive regulation of the macromitophagy pathway that is triggered by mitochondrial depolarization and requires the function of a DNM1L-family molecule. CHEBI:35405 transition element oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35405 GO:0061734 parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061734 Park2-mediated stimulation of mitophagy in response to mitochondrial depolarization|PRKN-mediated stimulation of mitophagy in response to mitochondrial depolarization A positive regulation of the macromitophagy pathway that is triggered by mitochondrial depolarization and requires the function of a parkin-family molecule. GO:0046119 7-methylguanosine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046119 7-methylguanosine degradation|7-methylguanosine breakdown|7-methylguanosine catabolism The chemical reactions and pathways resulting in the breakdown of 7-methylguanosine, a modified nucleoside that forms a cap at the 5'-terminus of eukaryotic mRNA. CHEBI:35404 chromate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35404 GO:0061737 leukotriene signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061737 A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-leukotriene interaction and ends with regulation of a downstream cellular process, e.g. transcription. GO:0061736 engulfment of target by autophagosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061736 The membrane invagination process by which an autophagosomal membrane surrounds an object that will be degraded by macroautophagy. GO:0061739 protein lipidation involved in autophagosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061739 The protein lipidation process by which phosphatidylethanolamine is conjugated to a protein of the ATG8 family, leading to membrane insertion of the protein as a step in autophagosome assembly. GO:0061738 late endosomal microautophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061738 The autophagy process by which cytosolic proteins targeted for degradation are tagged with a chaperone and are directly transferred into and degraded in a late endosomal compartment. SO:0001412 topologically_defined_region biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0001412 topologically defined region A DNA region within which self-interaction occurs more often than expected by chance because of DNA-looping. SO:0001411 biological_region biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0001411 INSDC_misc_feature|INSDC_note:biological_region|biological region A region defined by its disposition to be involved in a biological process. GO:0046121 deoxyribonucleoside catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046121 deoxyribonucleoside catabolism|deoxyribonucleoside degradation|deoxyribonucleoside breakdown The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside). UBERON:0012082 bronchial lumen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012082 bronchial lumen|lumen of bronchus An anatomical cavity that is part of a bronchus. UBERON:0012081 patella pre-cartilage condensation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012081 A pre-cartilage condensation that has the potential to develop into a patella. GO:0046120 deoxyribonucleoside biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046120 deoxyribonucleoside anabolism|deoxyribonucleoside synthesis|deoxyribonucleoside formation|deoxyribonucleoside biosynthesis The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside). UBERON:0012080 patella cartilage element biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012080 A cartilaginous condensation that has the potential to develop into a patella. UBERON:0012085 lumen of tertiary bronchus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012085 segmental bronchial lumen|lumen of segmental bronchus An anatomical cavity that is part of a segmental bronchus. UBERON:0012084 lumen of secondary bronchus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012084 lobar bronchial lumen|lumen of lobar bronchus|secondary bronchial lumen An anatomical cavity that is part of a lobar bronchus. GO:0046129 purine ribonucleoside biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046129 purine ribonucleoside anabolism|purine ribonucleoside synthesis|purine ribonucleoside formation|purine ribonucleoside biosynthesis The chemical reactions and pathways resulting in the formation of any purine ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule. GO:0046128 purine ribonucleoside metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046128 purine ribonucleoside metabolism The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule. GO:0046127 pyrimidine deoxyribonucleoside catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046127 pyrimidine deoxyribonucleoside degradation|pyrimidine deoxyribonucleoside breakdown|pyrimidine deoxyribonucleoside catabolism The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside). GO:0046126 pyrimidine deoxyribonucleoside biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046126 pyrimidine deoxyribonucleoside anabolism|pyrimidine deoxyribonucleoside synthesis|pyrimidine deoxyribonucleoside biosynthesis|pyrimidine deoxyribonucleoside formation The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside). GO:0046125 pyrimidine deoxyribonucleoside metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046125 pyrimidine deoxyribonucleoside metabolism The chemical reactions and pathways involving any one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside). GO:0046124 purine deoxyribonucleoside catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046124 purine deoxyribonucleoside degradation|purine deoxyribonucleoside breakdown|purine deoxyribonucleoside catabolism The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside). GO:0061760 antifungal innate immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061760 An defense response against a fungus mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens. GO:0046123 purine deoxyribonucleoside biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046123 purine deoxyribonucleoside biosynthesis|purine deoxyribonucleoside anabolism|purine deoxyribonucleoside synthesis|purine deoxyribonucleoside formation The chemical reactions and pathways resulting in the formation of any purine deoxyribonucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside). CHEBI:11408 2,3,4,5-tetrahydrodipicolinate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_11408 GO:0046122 purine deoxyribonucleoside metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046122 purine deoxyribonucleoside metabolism The chemical reactions and pathways involving any one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside). GO:0061762 CAMKK-AMPK signaling cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061762 stress-activated AMP-activated protein kinase signaling cascade A series of molecular signals in which calmodulin-dependent protein kinase activity enabled by a CAMKK directly activates an AMPK. The cascade begins with calmodulin binding calcium which in turn binds CAMKK enabling its calmodulin-dependent protein kinase activity. The cascade ends with AMP-activated protein kinase activity. GO:0061761 alpha-latrotoxin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061761 latrophilin binding|lasso receptor binding Interacting selectively and non-covalently with an alpha-latrotoxin receptor. GO:0061764 late endosome to lysosome transport via multivesicular body sorting pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061764 The directed movement of substances from late endosomes to lysosomes by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the lysosome. GO:0061763 multivesicular body-lysosome fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061763 MVB-lysosome fusion|fusion of MVB to lysosome|fusion of multivesicular body to lysosome The organelle membrane fusion process in which the membrane of a multivesicular body fuses with a lysosome to create a hybrid organelle. GO:0061766 positive regulation of lung blood pressure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061766 positive regulation of pulmonary blood pressure The process that increases the force with which blood travels through the lungs. GO:0061765 modulation by virus of host NIK/NF-kappaB signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061765 Any process in which a virus effect a change in the frequency, rate or extent of NIK/NF-kappaB signaling in the host. GO:0061768 magnesium:sodium antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061768 Catalysis of the reaction: Na+(in) + Mg2+(out) = Na+(out) + Mg2+(in). GO:0061767 negative regulation of lung blood pressure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061767 negative regulation of pulmonary blood pressure The process that decreases the force with which blood travels through the lungs. GO:0061769 ribosylnicotinate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061769 Reactome:R-HSA-8869607|Reactome:R-HSA-8869606 Catalysis of the reaction: N-ribosylnicotinate + ATP = ADP + 2 H(+) + nicotinate mononucleotide. GO:0046132 pyrimidine ribonucleoside biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046132 pyrimidine ribonucleoside biosynthesis|pyrimidine ribonucleoside formation|pyrimidine ribonucleoside anabolism|pyrimidine ribonucleoside synthesis The chemical reactions and pathways resulting in the formation of any ribonucleoside, a nucleoside in which a pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule. UBERON:0012071 palate bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012071 palatal bone Any bone that is part of a palate. GO:1900209 negative regulation of cardiolipin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900209 down regulation of cardiolipin metabolic process|down-regulation of diphosphatidylglycerol metabolism|negative regulation of diphosphatidylglycerol metabolism|inhibition of cardiolipin metabolism|downregulation of cardiolipin metabolic process|down-regulation of diphosphatidylglycerol metabolic process|negative regulation of diphosphatidylglycerol metabolic process|down-regulation of cardiolipin metabolic process|inhibition of diphosphatidylglycerol metabolism|downregulation of diphosphatidylglycerol metabolic process|down-regulation of cardiolipin metabolism|negative regulation of cardiolipin metabolism|down regulation of diphosphatidylglycerol metabolic process|inhibition of cardiolipin metabolic process|down regulation of diphosphatidylglycerol metabolism|downregulation of diphosphatidylglycerol metabolism|downregulation of cardiolipin metabolism|inhibition of diphosphatidylglycerol metabolic process|down regulation of cardiolipin metabolism Any process that stops, prevents or reduces the frequency, rate or extent of cardiolipin metabolic process. GO:0046131 pyrimidine ribonucleoside metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046131 pyrimidine ribonucleoside metabolism The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule. UBERON:0012070 palatal tooth biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012070 palatal teeth A tooth that is on the roof of the mouth. GO:0046130 purine ribonucleoside catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046130 purine ribonucleoside catabolism|purine ribonucleoside degradation|purine ribonucleoside breakdown The chemical reactions and pathways resulting in the breakdown of any purine ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule. GO:1900206 regulation of pronephric nephron tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900206 Any process that modulates the frequency, rate or extent of pronephric nephron tubule development. UBERON:0012075 replacement bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012075 replacement bones Bone that forms as a replacement of another structural tissue. GO:1900205 apoptotic process involved in metanephric nephron tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900205 programmed cell death by apoptosis of metanephric nephron tubule development|apoptosis of metanephric nephron tubule development|signaling (initiator) caspase activity of metanephric nephron tubule development|type I programmed cell death of metanephric nephron tubule development|apoptotic cell death of metanephric nephron tubule development|apoptotic process of metanephric nephron tubule development|apoptotic programmed cell death of metanephric nephron tubule development|apoptotic program of metanephric nephron tubule development Any apoptotic process that is involved in metanephric nephron tubule development. UBERON:0012074 bony part of hard palate biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012074 palatum osseum|hard palate skeleton|bony palate A subdivision of skeletal system that subdivision_of a hard palate. GO:1900208 regulation of cardiolipin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900208 regulation of diphosphatidylglycerol metabolic process|regulation of diphosphatidylglycerol metabolism|regulation of cardiolipin metabolism Any process that modulates the frequency, rate or extent of cardiolipin metabolic process. UBERON:0012073 tooth of palatine bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012073 palatine tooth|palatine teeth A tooth that is attached to a palatine bone. GO:1900207 negative regulation of pronephric nephron tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900207 inhibition of pronephric nephron tubule development|down regulation of pronephric nephron tubule development|downregulation of pronephric nephron tubule development|down-regulation of pronephric nephron tubule development Any process that stops, prevents or reduces the frequency, rate or extent of pronephric nephron tubule development. UBERON:0012072 palatal part of dermatocranium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012072 palatal series|dermatocranium, palatal series GO:1900202 obsolete negative regulation of spread of virus in host, cell to cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900202 inhibition of cell to cell spread of virus within host|inhibition of spread of virus within host, cell to cell|down regulation of spread of virus in host, cell to cell|inhibition of viral spread within host, cell to cell|downregulation of spread of virus in host, cell to cell|down regulation of spread of virus within host, cell to cell|downregulation of spread of virus within host, cell to cell|down-regulation of cell to cell spread of virus within host|negative regulation of cell to cell spread of virus within host|down-regulation of spread of virus in host, cell to cell|negative regulation of viral spread within host, cell to cell|down-regulation of viral spread within host, cell to cell|inhibition of spread of virus in host, cell to cell|down-regulation of spread of virus within host, cell to cell|negative regulation of spread of virus within host, cell to cell|downregulation of cell to cell spread of virus within host|down regulation of cell to cell spread of virus within host|downregulation of viral spread within host, cell to cell|down regulation of viral spread within host, cell to cell|negative regulation of spread of virus in host, cell to cell OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of spread of virus in host, cell to cell. GO:0046139 obsolete coenzyme and prosthetic group catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046139 coenzyme and prosthetic group catabolism|coenzyme and prosthetic group degradation|coenzyme and prosthetic group breakdown|coenzyme and prosthetic group catabolic process OBSOLETE. The chemical reactions and pathways resulting in the breakdown of coenzymes and prosthetic groups. GO:1900201 obsolete regulation of spread of virus in host, cell to cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900201 regulation of spread of virus within host, cell to cell|regulation of spread of virus in host, cell to cell|regulation of cell to cell spread of virus within host|regulation of viral spread within host, cell to cell OBSOLETE. Any process that modulates the frequency, rate or extent of spread of virus in host, cell to cell. GO:0046138 obsolete coenzyme and prosthetic group biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046138 coenzyme and prosthetic group synthesis|coenzyme and prosthetic group formation|coenzyme and prosthetic group biosynthetic process|coenzyme and prosthetic group biosynthesis|coenzyme and prosthetic group anabolism OBSOLETE. The chemical reactions and pathways resulting in the formation of coenzymes and prosthetic groups. GO:1900204 apoptotic process involved in metanephric collecting duct development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900204 type I programmed cell death of metanephric collecting duct development|apoptosis of metanephric collecting duct development|apoptotic programmed cell death of metanephric collecting duct development|apoptotic process of metanephric collecting duct development|apoptotic cell death of metanephric collecting duct development|programmed cell death by apoptosis of metanephric collecting duct development|signaling (initiator) caspase activity of metanephric collecting duct development|apoptotic program of metanephric collecting duct development Any apoptotic process that is involved in metanephric collecting duct development. GO:0046137 negative regulation of vitamin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046137 inhibition of vitamin metabolic process|down regulation of vitamin metabolic process|downregulation of vitamin metabolic process|down-regulation of vitamin metabolic process|negative regulation of vitamin metabolism Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. GO:1900203 obsolete positive regulation of spread of virus in host, cell to cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900203 upregulation of viral spread within host, cell to cell|upregulation of spread of virus within host, cell to cell|up-regulation of cell to cell spread of virus within host|up regulation of spread of virus in host, cell to cell|up-regulation of viral spread within host, cell to cell|activation of spread of virus in host, cell to cell|activation of cell to cell spread of virus within host|up regulation of spread of virus within host, cell to cell|activation of viral spread within host, cell to cell|positive regulation of cell to cell spread of virus within host|positive regulation of spread of virus within host, cell to cell|up regulation of cell to cell spread of virus within host|positive regulation of viral spread within host, cell to cell|up-regulation of spread of virus in host, cell to cell|activation of spread of virus within host, cell to cell|up regulation of viral spread within host, cell to cell|up-regulation of spread of virus within host, cell to cell|positive regulation of spread of virus in host, cell to cell|upregulation of cell to cell spread of virus within host|upregulation of spread of virus in host, cell to cell OBSOLETE. Any process that activates or increases the frequency, rate or extent of spread of virus in host, cell to cell. GO:0046136 positive regulation of vitamin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046136 positive regulation of vitamin metabolism|up-regulation of vitamin metabolic process|upregulation of vitamin metabolic process|up regulation of vitamin metabolic process|activation of vitamin metabolic process|stimulation of vitamin metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. GO:0046135 pyrimidine nucleoside catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046135 pyrimidine nucleoside degradation|pyrimidine nucleoside breakdown|pyrimidine nucleoside catabolism The chemical reactions and pathways resulting in the breakdown of one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside). GO:0046134 pyrimidine nucleoside biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046134 pyrimidine nucleoside anabolism|pyrimidine nucleoside synthesis|pyrimidine nucleoside formation|pyrimidine nucleoside biosynthesis The chemical reactions and pathways resulting in the formation of one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside). GO:1900200 mesenchymal cell apoptotic process involved in metanephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900200 mesenchymal cell apoptosis involved in metanephros development Any mesenchymal cell apoptotic process that is involved in metanephros development. GO:0046133 pyrimidine ribonucleoside catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046133 pyrimidine ribonucleoside degradation|pyrimidine ribonucleoside breakdown|pyrimidine ribonucleoside catabolism The chemical reactions and pathways resulting in the breakdown of any ribonucleoside, a nucleoside in which a pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule. GO:0061751 neutral sphingomyelin phosphodiesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061751 neutral SMase|neutral sphingomyelinase Catalysis of the reaction: H(2)O + sphingomyelin = ceramide + choline phosphate + H(+) in a neutral environment. GO:0061750 acid sphingomyelin phosphodiesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061750 acid SMase|acid sphingomyelinase Catalysis of the reaction: H(2)O + sphingomyelin = ceramide + choline phosphate + H(+) in an acidic environment. GO:0061753 substrate localization to autophagosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061753 substrate sequestration to autophagosome|substrate sequestration to phagophore The localization process by which an autophagic substrate is delivered to a forming autophagosome. GO:0061752 telomeric repeat-containing RNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061752 TERRA binding Interacting selectively and non-covalently with long non-coding RNA molecules transcribed from subtelomeric regions in most eukaryotes. Telomeric repeat-containing RNA (TERRA) molecules consist of subtelomeric-derived sequences and G-rich telomeric repeats. GO:0061755 positive regulation of circulating fibrinogen levels biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061755 Any process that increases the quantity of fibrinogen circulating in the bloodstream. GO:0061754 negative regulation of circulating fibrinogen levels biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061754 Any process that reduces the quantity of fibrinogen circulating in the bloodstream. GO:0061757 leukocyte adhesion to arterial endothelial cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061757 The attachment of a leukocyte to an arterial endothelial cell via adhesion molecules. GO:0061756 leukocyte adhesion to vascular endothelial cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061756 The attachment of a leukocyte to vascular endothelial cell via adhesion molecules. GO:0061759 alpha-ketoglutarate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061759 RHEA:21254 2-oxoglutarate reductase activity|2-hydroxyglutarate dehydrogenase activity, reverse reaction|D-2HG reductase activity|2-ketoglutarate reductase activity Catalysis of the reaction: 2-oxoglutarate + reduced acceptor -> (S)-2-hydroxyglutarate + acceptor. GO:0061758 2-hydroxyglutarate dehydrogenase activity, forward reaction biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061758 RHEA:21253 alpha-ketoglutarate reductase activity, reverse reaction Catalysis of the reaction: (S)-2-hydroxyglutarate + acceptor -> 2-oxoglutarate + reduced acceptor. GO:0046143 obsolete positive regulation of coenzyme and prosthetic group metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046143 positive regulation of coenzyme and prosthetic group metabolic process OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving coenzymes and prosthetic groups. GO:0046142 obsolete negative regulation of coenzyme and prosthetic group metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046142 negative regulation of coenzyme and prosthetic group metabolic process OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving coenzymes and prosthetic groups. GO:0046141 corrin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046141 corrin degradation|corrin breakdown|corrin catabolism The chemical reactions and pathways resulting in the breakdown of corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule. GO:0046140 corrin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046140 corrin biosynthesis|corrin anabolism|corrin synthesis|corrin formation The chemical reactions and pathways resulting in the formation of corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule. GO:1900217 regulation of apoptotic process involved in metanephric nephron tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900217 regulation of signaling (initiator) caspase activity of metanephric nephron tubule development|regulation of type I programmed cell death of metanephric nephron tubule development|regulation of apoptotic cell death of metanephric nephron tubule development|regulation of apoptosis of metanephric nephron tubule development|regulation of apoptotic process of metanephric nephron tubule development|regulation of apoptotic programmed cell death of metanephric nephron tubule development|regulation of apoptotic program of metanephric nephron tubule development|regulation of programmed cell death by apoptosis of metanephric nephron tubule development Any process that modulates the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development. GO:1900216 positive regulation of apoptotic process involved in metanephric collecting duct development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900216 up regulation of programmed cell death by apoptosis of metanephric collecting duct development|upregulation of apoptotic program of metanephric collecting duct development|activation of apoptotic process of metanephric collecting duct development|up regulation of apoptosis of metanephric collecting duct development|upregulation of apoptotic process involved in metanephric collecting duct development|positive regulation of programmed cell death by apoptosis of metanephric collecting duct development|positive regulation of apoptotic programmed cell death of metanephric collecting duct development|positive regulation of apoptotic process of metanephric collecting duct development|up-regulation of apoptotic cell death of metanephric collecting duct development|up regulation of signaling (initiator) caspase activity of metanephric collecting duct development|up regulation of apoptotic programmed cell death of metanephric collecting duct development|upregulation of type I programmed cell death of metanephric collecting duct development|up regulation of apoptotic process of metanephric collecting duct development|positive regulation of signaling (initiator) caspase activity of metanephric collecting duct development|activation of programmed cell death by apoptosis of metanephric collecting duct development|up-regulation of apoptotic program of metanephric collecting duct development|upregulation of apoptosis of metanephric collecting duct development|up regulation of apoptotic process involved in metanephric collecting duct development|activation of signaling (initiator) caspase activity of metanephric collecting duct development|up-regulation of programmed cell death by apoptosis of metanephric collecting duct development|activation of apoptotic process involved in metanephric collecting duct development|upregulation of apoptotic cell death of metanephric collecting duct development|activation of apoptotic program of metanephric collecting duct development|up regulation of type I programmed cell death of metanephric collecting duct development|upregulation of apoptotic programmed cell death of metanephric collecting duct development|upregulation of apoptotic process of metanephric collecting duct development|up-regulation of signaling (initiator) caspase activity of metanephric collecting duct development|positive regulation of type I programmed cell death of metanephric collecting duct development|up-regulation of apoptosis of metanephric collecting duct development|positive regulation of apoptotic program of metanephric collecting duct development|up regulation of apoptotic program of metanephric collecting duct development|upregulation of programmed cell death by apoptosis of metanephric collecting duct development|activation of type I programmed cell death of metanephric collecting duct development|up regulation of apoptotic cell death of metanephric collecting duct development|up-regulation of apoptotic process involved in metanephric collecting duct development|up-regulation of apoptotic programmed cell death of metanephric collecting duct development|up-regulation of apoptotic process of metanephric collecting duct development|positive regulation of apoptotic cell death of metanephric collecting duct development|activation of apoptosis of metanephric collecting duct development|upregulation of signaling (initiator) caspase activity of metanephric collecting duct development|up-regulation of type I programmed cell death of metanephric collecting duct development|activation of apoptotic programmed cell death of metanephric collecting duct development|activation of apoptotic cell death of metanephric collecting duct development|positive regulation of apoptosis of metanephric collecting duct development Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development. GO:1900219 positive regulation of apoptotic process involved in metanephric nephron tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900219 up regulation of apoptotic cell death of metanephric nephron tubule development|activation of apoptotic process involved in metanephric nephron tubule development|upregulation of programmed cell death by apoptosis of metanephric nephron tubule development|upregulation of apoptosis of metanephric nephron tubule development|up-regulation of apoptotic program of metanephric nephron tubule development|upregulation of type I programmed cell death of metanephric nephron tubule development|upregulation of apoptotic process of metanephric nephron tubule development|upregulation of signaling (initiator) caspase activity of metanephric nephron tubule development|upregulation of apoptotic programmed cell death of metanephric nephron tubule development|upregulation of apoptotic cell death of metanephric nephron tubule development|up-regulation of programmed cell death by apoptosis of metanephric nephron tubule development|up regulation of apoptotic process involved in metanephric nephron tubule development|up regulation of apoptosis of metanephric nephron tubule development|upregulation of apoptotic program of metanephric nephron tubule development|positive regulation of apoptosis of metanephric nephron tubule development|up-regulation of type I programmed cell death of metanephric nephron tubule development|up-regulation of signaling (initiator) caspase activity of metanephric nephron tubule development|up regulation of apoptotic process of metanephric nephron tubule development|activation of programmed cell death by apoptosis of metanephric nephron tubule development|up regulation of apoptotic programmed cell death of metanephric nephron tubule development|positive regulation of apoptotic process of metanephric nephron tubule development|up-regulation of apoptotic cell death of metanephric nephron tubule development|activation of apoptosis of metanephric nephron tubule development|positive regulation of apoptotic programmed cell death of metanephric nephron tubule development|positive regulation of programmed cell death by apoptosis of metanephric nephron tubule development|activation of signaling (initiator) caspase activity of metanephric nephron tubule development|upregulation of apoptotic process involved in metanephric nephron tubule development|activation of type I programmed cell death of metanephric nephron tubule development|up regulation of apoptotic program of metanephric nephron tubule development|activation of apoptotic process of metanephric nephron tubule development|up regulation of programmed cell death by apoptosis of metanephric nephron tubule development|up-regulation of apoptosis of metanephric nephron tubule development|positive regulation of apoptotic program of metanephric nephron tubule development|activation of apoptotic cell death of metanephric nephron tubule development|activation of apoptotic programmed cell death of metanephric nephron tubule development|positive regulation of type I programmed cell death of metanephric nephron tubule development|positive regulation of signaling (initiator) caspase activity of metanephric nephron tubule development|up regulation of signaling (initiator) caspase activity of metanephric nephron tubule development|up regulation of type I programmed cell death of metanephric nephron tubule development|up-regulation of apoptotic process of metanephric nephron tubule development|activation of apoptotic program of metanephric nephron tubule development|positive regulation of apoptotic cell death of metanephric nephron tubule development|up-regulation of apoptotic programmed cell death of metanephric nephron tubule development|up-regulation of apoptotic process involved in metanephric nephron tubule development Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development. GO:1900218 negative regulation of apoptotic process involved in metanephric nephron tubule development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900218 downregulation of apoptotic cell death of metanephric nephron tubule development|down regulation of type I programmed cell death of metanephric nephron tubule development|down regulation of signaling (initiator) caspase activity of metanephric nephron tubule development|inhibition of apoptotic process of metanephric nephron tubule development|inhibition of apoptotic programmed cell death of metanephric nephron tubule development|down regulation of apoptosis of metanephric nephron tubule development|inhibition of programmed cell death by apoptosis of metanephric nephron tubule development|down-regulation of apoptotic process involved in metanephric nephron tubule development|down regulation of apoptotic cell death of metanephric nephron tubule development|downregulation of apoptosis of metanephric nephron tubule development|inhibition of apoptotic program of metanephric nephron tubule development|inhibition of type I programmed cell death of metanephric nephron tubule development|inhibition of signaling (initiator) caspase activity of metanephric nephron tubule development|down regulation of apoptotic process of metanephric nephron tubule development|down regulation of apoptotic programmed cell death of metanephric nephron tubule development|inhibition of apoptotic cell death of metanephric nephron tubule development|downregulation of apoptotic process of metanephric nephron tubule development|down regulation of apoptotic program of metanephric nephron tubule development|downregulation of apoptotic process involved in metanephric nephron tubule development|downregulation of apoptotic programmed cell death of metanephric nephron tubule development|negative regulation of apoptosis of metanephric nephron tubule development|down-regulation of apoptosis of metanephric nephron tubule development|down-regulation of programmed cell death by apoptosis of metanephric nephron tubule development|negative regulation of programmed cell death by apoptosis of metanephric nephron tubule development|down regulation of apoptotic process involved in metanephric nephron tubule development|downregulation of apoptotic program of metanephric nephron tubule development|inhibition of apoptotic process involved in metanephric nephron tubule development|down-regulation of signaling (initiator) caspase activity of metanephric nephron tubule development|negative regulation of signaling (initiator) caspase activity of metanephric nephron tubule development|negative regulation of type I programmed cell death of metanephric nephron tubule development|down-regulation of type I programmed cell death of metanephric nephron tubule development|down-regulation of apoptotic process of metanephric nephron tubule development|negative regulation of apoptotic process of metanephric nephron tubule development|negative regulation of apoptotic programmed cell death of metanephric nephron tubule development|down-regulation of apoptotic programmed cell death of metanephric nephron tubule development|negative regulation of apoptotic cell death of metanephric nephron tubule development|down-regulation of apoptotic cell death of metanephric nephron tubule development|downregulation of programmed cell death by apoptosis of metanephric nephron tubule development|down-regulation of apoptotic program of metanephric nephron tubule development|negative regulation of apoptotic program of metanephric nephron tubule development|inhibition of apoptosis of metanephric nephron tubule development|downregulation of type I programmed cell death of metanephric nephron tubule development|down regulation of programmed cell death by apoptosis of metanephric nephron tubule development|downregulation of signaling (initiator) caspase activity of metanephric nephron tubule development Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development. GO:1900213 positive regulation of mesenchymal cell apoptotic process involved in metanephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900213 up regulation of mesenchymal cell apoptosis involved in metanephros development|upregulation of mesenchymal cell apoptosis involved in metanephros development|positive regulation of mesenchymal cell apoptosis involved in metanephros development|up-regulation of mesenchymal cell apoptosis involved in metanephros development|activation of mesenchymal cell apoptosis involved in metanephros development Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development. GO:1900212 negative regulation of mesenchymal cell apoptotic process involved in metanephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900212 downregulation of mesenchymal cell apoptosis involved in metanephros development|negative regulation of mesenchymal cell apoptosis involved in metanephros development|down regulation of mesenchymal cell apoptosis involved in metanephros development|inhibition of mesenchymal cell apoptosis involved in metanephros development|down-regulation of mesenchymal cell apoptosis involved in metanephros development Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development. GO:1900215 negative regulation of apoptotic process involved in metanephric collecting duct development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900215 down-regulation of apoptotic process of metanephric collecting duct development|negative regulation of apoptotic process of metanephric collecting duct development|downregulation of signaling (initiator) caspase activity of metanephric collecting duct development|inhibition of type I programmed cell death of metanephric collecting duct development|downregulation of apoptosis of metanephric collecting duct development|inhibition of apoptotic program of metanephric collecting duct development|down regulation of apoptotic process involved in metanephric collecting duct development|down-regulation of programmed cell death by apoptosis of metanephric collecting duct development|negative regulation of programmed cell death by apoptosis of metanephric collecting duct development|downregulation of apoptotic process involved in metanephric collecting duct development|downregulation of apoptotic programmed cell death of metanephric collecting duct development|down regulation of apoptosis of metanephric collecting duct development|inhibition of apoptotic cell death of metanephric collecting duct development|downregulation of apoptotic process of metanephric collecting duct development|down regulation of type I programmed cell death of metanephric collecting duct development|negative regulation of signaling (initiator) caspase activity of metanephric collecting duct development|down-regulation of signaling (initiator) caspase activity of metanephric collecting duct development|down regulation of apoptotic programmed cell death of metanephric collecting duct development|down regulation of apoptotic process of metanephric collecting duct development|downregulation of type I programmed cell death of metanephric collecting duct development|inhibition of apoptosis of metanephric collecting duct development|down regulation of apoptotic cell death of metanephric collecting duct development|negative regulation of apoptotic program of metanephric collecting duct development|down-regulation of apoptotic program of metanephric collecting duct development|down-regulation of apoptotic process involved in metanephric collecting duct development|inhibition of programmed cell death by apoptosis of metanephric collecting duct development|inhibition of apoptotic programmed cell death of metanephric collecting duct development|downregulation of apoptotic cell death of metanephric collecting duct development|inhibition of apoptotic process of metanephric collecting duct development|down-regulation of type I programmed cell death of metanephric collecting duct development|negative regulation of type I programmed cell death of metanephric collecting duct development|inhibition of signaling (initiator) caspase activity of metanephric collecting duct development|down regulation of programmed cell death by apoptosis of metanephric collecting duct development|inhibition of apoptotic process involved in metanephric collecting duct development|downregulation of apoptotic program of metanephric collecting duct development|down-regulation of apoptosis of metanephric collecting duct development|negative regulation of apoptosis of metanephric collecting duct development|downregulation of programmed cell death by apoptosis of metanephric collecting duct development|down regulation of signaling (initiator) caspase activity of metanephric collecting duct development|down regulation of apoptotic program of metanephric collecting duct development|negative regulation of apoptotic cell death of metanephric collecting duct development|down-regulation of apoptotic cell death of metanephric collecting duct development|down-regulation of apoptotic programmed cell death of metanephric collecting duct development|negative regulation of apoptotic programmed cell death of metanephric collecting duct development Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development. GO:0046149 pigment catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046149 pigment degradation|pigment breakdown|pigment catabolism The chemical reactions and pathways resulting in the breakdown of a pigment, any general or particular coloring matter in living organisms, e.g. melanin. GO:0046148 pigment biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046148 pigment biosynthesis|pigment synthesis|pigment formation|pigment anabolism The chemical reactions and pathways resulting in the formation of a pigment, any general or particular coloring matter in living organisms, e.g. melanin. GO:1900214 regulation of apoptotic process involved in metanephric collecting duct development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900214 regulation of apoptosis of metanephric collecting duct development|regulation of apoptotic programmed cell death of metanephric collecting duct development|regulation of type I programmed cell death of metanephric collecting duct development|regulation of apoptotic process of metanephric collecting duct development|regulation of apoptotic cell death of metanephric collecting duct development|regulation of apoptotic program of metanephric collecting duct development|regulation of programmed cell death by apoptosis of metanephric collecting duct development|regulation of signaling (initiator) caspase activity of metanephric collecting duct development Any process that modulates the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development. GO:0046147 tetrahydrobiopterin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046147 5,6,7,8-tetrahydrobiopterin catabolic process|tetrahydrobiopterin catabolism|tetrahydrobiopterin degradation|tetrahydrobiopterin breakdown The chemical reactions and pathways resulting in the breakdown of tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine. GO:0061780 mitotic cohesin loading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061780 The protein localization to chromatin by which a cohesin ring complex is topologically linked to DNA as part of the mitotic cell cycle. GO:0046146 tetrahydrobiopterin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046146 tetrahydrobiopterin metabolism|5,6,7,8-tetrahydrobiopterin metabolic process The chemical reactions and pathways involving tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine. GO:1900211 regulation of mesenchymal cell apoptotic process involved in metanephros development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900211 regulation of mesenchymal cell apoptosis involved in metanephros development Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development. GO:0061782 vesicle fusion with vesicle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061782 vesicle to vesicle fusion|vesicle-vesicle fusion Fusion of the membrane of a transport vesicle with a target membrane on another vesicle. GO:0046145 D-alanine family amino acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046145 D-alanine family amino acid anabolism|D-alanine family amino acid biosynthesis|D-alanine family amino acid synthesis|D-alanine family amino acid formation The chemical reactions and pathways resulting in the formation of D-alanine and related amino acids. GO:0046144 D-alanine family amino acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046144 D-alanine family amino acid metabolism The chemical reactions and pathways involving D-alanine and related amino acids. GO:0061781 mitotic cohesin unloading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061781 Negative regulation of sister chromatid cohesion by the topological unlinking of a cohesin ring to DNA as part of the mitotic cell cycle. GO:1900210 positive regulation of cardiolipin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900210 up regulation of diphosphatidylglycerol metabolism|positive regulation of diphosphatidylglycerol metabolism|upregulation of cardiolipin metabolic process|up-regulation of diphosphatidylglycerol metabolic process|upregulation of cardiolipin metabolism|activation of diphosphatidylglycerol metabolism|activation of diphosphatidylglycerol metabolic process|up regulation of cardiolipin metabolic process|up-regulation of diphosphatidylglycerol metabolism|up-regulation of cardiolipin metabolism|positive regulation of diphosphatidylglycerol metabolic process|activation of cardiolipin metabolic process|up regulation of diphosphatidylglycerol metabolic process|activation of cardiolipin metabolism|upregulation of diphosphatidylglycerol metabolism|positive regulation of cardiolipin metabolism|up-regulation of cardiolipin metabolic process|up regulation of cardiolipin metabolism|upregulation of diphosphatidylglycerol metabolic process Any process that activates or increases the frequency, rate or extent of cardiolipin metabolic process. UBERON:0012069 epithelium-associated lymphoid tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012069 CHEBI:11421 2,3-dihydrodipicolinate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_11421 GO:0061784 peptidoglycan N-acetylglucosaminidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061784 Catalysis of the hydrolysis of (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) from peptidoglycan. GO:0061783 peptidoglycan muralytic activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061783 A catalytic activity that contributes to the degradation of peptidoglycan. GO:0061786 peptidoglycan stem peptide endopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061786 A peptidoglycan endopeptidase activity that acts on a stem peptide of peptidoglycan. GO:0061785 peptidoglycan endopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061785 An endopeptidase activity that uses peptidoglycan as a substrate. GO:0061788 EGF repeat binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061788 Epidermal growth factor domain binding|Epidermal Growth Factor repeat binding Interacting selectively and non-covalently with Epidermal Growth Factor (EGF) repeats. GO:0061787 peptidoglycan cross-bridge peptide endopeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061787 lysostaphin activity A peptidoglycan endopeptidase activity that acts on a peptidoglycan cross-bridge. CHEBI:11424 2,3-dihydroxy-3-methylbutanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_11424 GO:0071109 superior temporal gyrus development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071109 The process whose specific outcome is the progression of the superior temporal gyrus over time, from its formation to the mature structure. The superior temporal gyrus is a portion of the cerebral cortex that extends from the lateral sulcus to the superior temporal sulcus. GO:0071108 protein K48-linked deubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071108 A protein deubiquitination process in which a K48-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is removed from a protein. GO:0061789 dense core granule priming biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061789 LDCV priming|dense core vesicle priming|large dense-core vesicle priming A process that converts unprimed dense core granules (DCVs) to a pool of primed vesicles that are capable of fusing with the plasma membrane (fusion-competent) and thereby releasing their contents. Priming typically occurs after docking. GO:0071107 response to parathyroid hormone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071107 response to parathyroid hormone stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a parathyroid hormone stimulus. GO:0071106 adenosine 3',5'-bisphosphate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071106 adenosine 3'-phosphate-5'-phosphate transmembrane transport|adenosine 3',5'-bisphosphate membrane transport|adenosine 3',5'-diphosphate transport The process in which adenosine 3',5'-bisphosphate is transported across a membrane. GO:0071105 response to interleukin-11 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071105 response to IL-11 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-11 stimulus. GO:0071104 response to interleukin-9 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071104 response to IL-9 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-9 stimulus. GO:0071103 DNA conformation change biolink:BiologicalProcess go-plus goslim_metagenomics http://purl.obolibrary.org/obo/GO_0071103 DNA conformation modification A cellular process that results in a change in the spatial configuration of a DNA molecule. A conformation change can bend DNA, or alter the, twist, writhe, or linking number of a DNA molecule. GO:0071102 alpha4-beta1 integrin-paxillin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071102 ITGA4-ITGB1-PXN complex A protein complex that consists of an alpha4-beta1 integrin complex bound to paxillin. GO:0071101 alpha4-beta1 integrin-JAM2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071101 ITGA4-ITGB1-JAM2 complex A protein complex that consists of an alpha4-beta1 integrin complex bound to the cell adhesion molecule JAM2. GO:0071100 alphaV-beta8 integrin-MMP14-TGFbeta-1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071100 ITGAV-ITGB8-MMP14-TGFB1 complex A protein complex that consists of an alphaV-beta8 integrin complex bound to matrix metalloproteinase 14 and transforming growth factor beta-1 (TGFbeta-1). GO:0046154 rhodopsin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046154 rhodopsin metabolism The chemical reactions and pathways involving rhodopsin, a brilliant purplish-red, light-sensitive visual pigment found in the rod cells of the retinas. GO:0046153 ommochrome catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046153 ommochrome degradation|ommochrome breakdown|ommochrome catabolism The chemical reactions and pathways resulting in the breakdown of ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye. GO:0046152 ommochrome metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046152 ommochrome metabolism The chemical reactions and pathways involving ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye. GO:0046151 eye pigment catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046151 eye pigment degradation|eye pigment breakdown|eye pigment catabolism The chemical reactions and pathways resulting in the breakdown of eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye. GO:0046150 melanin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046150 melanin catabolism|melanin breakdown|melanin degradation The chemical reactions and pathways resulting in the breakdown of melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom. GO:1900228 regulation of single-species biofilm formation in or on host organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900228 Any process that modulates the frequency, rate or extent of single-species biofilm formation in or on host organism. GO:1900227 positive regulation of NLRP3 inflammasome complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900227 positive regulation of NLRP3 inflammasome activation|up-regulation of NALP3 inflammasome complex assembly|activation of NLRP3 inflammasome activation|up-regulation of NLRP3 inflammasome complex assembly|upregulation of NALP3 inflammasome complex assembly|up-regulation of NLRP3 inflammasome activation|upregulation of NLRP3 inflammasome complex assembly|upregulation of NLRP3 inflammasome activation|up regulation of NALP3 inflammasome complex assembly|positive regulation of NALP3 inflammasome complex assembly|up regulation of NLRP3 inflammasome complex assembly|activation of NLRP3 inflammasome complex assembly|activation of NALP3 inflammasome complex assembly|up regulation of NLRP3 inflammasome activation Any process that activates or increases the frequency, rate or extent of NLRP3 inflammasome complex assembly. GO:1900229 negative regulation of single-species biofilm formation in or on host organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900229 down regulation of single-species biofilm formation in or on host organism|downregulation of single-species biofilm formation in or on host organism|down-regulation of single-species biofilm formation in or on host organism|inhibition of single-species biofilm formation in or on host organism Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation in or on host organism. GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900224 upregulation of nodal signaling of determination of left/right asymmetry in lateral mesoderm|up regulation of nodal signaling pathway of determination of left/right asymmetry in lateral mesoderm|upregulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry|positive regulation of nodal signalling pathway involved in determination of lateral mesoderm left/right asymmetry|up-regulation of nodal signaling of determination of left/right asymmetry in lateral mesoderm|upregulation of nodal signaling pathway of determination of left/right asymmetry in lateral mesoderm|up-regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry|activation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry|activation of nodal signaling of determination of left/right asymmetry in lateral mesoderm|up-regulation of nodal signaling pathway of determination of left/right asymmetry in lateral mesoderm|positive regulation of nodal signaling of determination of left/right asymmetry in lateral mesoderm|up regulation of nodal signaling of determination of left/right asymmetry in lateral mesoderm|activation of nodal signaling pathway of determination of left/right asymmetry in lateral mesoderm|up regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry|positive regulation of nodal signaling pathway of determination of left/right asymmetry in lateral mesoderm Any process that activates or increases the frequency, rate or extent of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry. GO:1900223 positive regulation of amyloid-beta clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900223 up regulation of beta-amyloid clearance|upregulation of beta-amyloid clearance|positive regulation of beta-amyloid clearance|up-regulation of beta-amyloid clearance|activation of beta-amyloid clearance Any process that activates or increases the frequency, rate or extent of amyloid-beta clearance. GO:1900226 negative regulation of NLRP3 inflammasome complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900226 down-regulation of NLRP3 inflammasome activation|negative regulation of NLRP3 inflammasome activation|inhibition of NLRP3 inflammasome complex assembly|inhibition of NALP3 inflammasome complex assembly|down regulation of NALP3 inflammasome complex assembly|inhibition of NLRP3 inflammasome activation|downregulation of NALP3 inflammasome complex assembly|down regulation of NLRP3 inflammasome complex assembly|downregulation of NLRP3 inflammasome complex assembly|down regulation of NLRP3 inflammasome activation|negative regulation of NALP3 inflammasome complex assembly|down-regulation of NALP3 inflammasome complex assembly|downregulation of NLRP3 inflammasome activation|down-regulation of NLRP3 inflammasome complex assembly Any process that stops, prevents or reduces the frequency, rate or extent of NLRP3 inflammasome complex assembly. UBERON:0012054 myocoele biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012054 The cavity within a myotome GO:1900225 regulation of NLRP3 inflammasome complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900225 regulation of NALP3 inflammasome complex assembly|regulation of NLRP3 inflammasome activation Any process that modulates the frequency, rate or extent of NLRP3 inflammasome complex assembly. GO:0046159 ocellus pigment catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046159 ocellus pigment degradation|ocellus pigment breakdown|ocellus pigment catabolism The chemical reactions and pathways resulting in the breakdown of ocellus pigments, any general or particular coloring matter in living organisms, found or utilized in the ocellus, a minute simple eye found in many invertebrates. GO:0046158 ocellus pigment metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046158 ocellus pigment metabolism The chemical reactions and pathways involving ocellus pigments, any general or particular coloring matter in living organisms, found or utilized in the ocellus, a minute simple eye found in many invertebrates. GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900220 semaphorin-plexin signalling pathway of bone trabecula morphogenesis|semaphorin-plexin signaling pathway of bone trabecula morphogenesis Any semaphorin-plexin signaling pathway that contributes to bone trabecula morphogenesis. GO:0046157 siroheme catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046157 siroheme degradation|siroheme breakdown|siroheme catabolism|sirohaem catabolism|sirohaem catabolic process The chemical reactions and pathways resulting in the breakdown of siroheme, a tetrahydroporphyrin with adjacent, reduced pyrrole rings. GO:0046156 siroheme metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046156 siroheme metabolism|sirohaem metabolic process|sirohaem metabolism The chemical reactions and pathways involving siroheme, a tetrahydroporphyrin with adjacent, reduced pyrrole rings. GO:1900222 negative regulation of amyloid-beta clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900222 down-regulation of beta-amyloid clearance|downregulation of beta-amyloid clearance|down regulation of beta-amyloid clearance|inhibition of beta-amyloid clearance|negative regulation of beta-amyloid clearance Any process that stops, prevents or reduces the frequency, rate or extent of amyloid-beta clearance. GO:0061771 response to caloric restriction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061771 A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caloric restriction, insufficient food energy intake. GO:1900221 regulation of amyloid-beta clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900221 regulation of beta-amyloid clearance Any process that modulates the frequency, rate or extent of amyloid-beta clearance. GO:0046155 rhodopsin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046155 rhodopsin breakdown|rhodopsin catabolism|rhodopsin degradation The chemical reactions and pathways resulting in the breakdown of rhodopsin, a brilliant purplish-red, light-sensitive visual pigment found in the rod cells of the retinas. GO:0061770 translation elongation factor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061770 Interacting selectively and non-covalently with a translation elongation factor, any polypeptide factor involved in the peptide elongation in ribosome-mediated translation. GO:0061773 eNoSc complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061773 energy dependent nucleolar silencing complex A chromatin silencing complex that recruits histone-modifying enzymes and upregulates silencing of rDNA in response to glucose starvation. GO:0061772 xenobiotic transport across blood-nerve barrier biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061772 drug transport across blood-nerve barrier|drug transport across perineurial barrier The directed movement of a xenobiotic through the blood-nerve barrier. GO:0061775 cohesin ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061775 Catalysis of the reaction: ATP + H2O = ADP + phosphate, coupled to the topological linking or unlinking of a cohesin ring complex around homologous chromosomes. GO:0061774 cohesin unloading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061774 DNA exit from the cohesin ring Negative regulation of sister chromatid cohesion by the topological unlinking of a cohesin ring to DNA. GO:0061777 obsolete DNA clamp activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061777 OBSOLETE. A DNA binding activity in which a protein complex interacts selectively and non-covalently with single DNA duplex to tightly encircle the DNA. GO:0061776 topological DNA entrapment activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061776 The DNA binding activity by which a protein complex interacts selectively and non-covalently with more than one DNA duplex to encircle the DNA molecules with a loose fitting ring. CHEBI:11412 (2R,3S,4S)-leucocyanidin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_11412 GO:0061779 Tapasin-ERp57 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061779 Subunit of the MHC class I peptide loading complex (GO:0042824) (=PLC) involved in the assembly of the heavy-chain-beta2-microglobulin dimers of the MHC class I molecules that fold with eight to ten residue peptides in the endoplasmic reticulum. Required for the inhibition of the reduction of the disulfide bonds of the heavy chains and the assembly and stabilization of the PLC, suggesting it may play a structural rather than a catalytic role. GO:0061778 intracellular chloride channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061778 Enables the transmembrane transfer of chloride across the membrane of an intracellular compartment. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism. CHEBI:74986 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74986 CHEBI:84305 2-carboxyhexacosanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84305 CHEBI:84303 2-carboxytetracosanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84303 CHEBI:84302 trilinoleoyl 2-monolysocardiolipin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84302 CHEBI:60344 ferroheme b(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60344 CHEBI:84300 1-myristoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84300 CHEBI:60345 organic phosphoramidate anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60345 CHEBI:35378 glycosylfructose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35378 CHEBI:35371 lipooligosaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35371 CHEBI:35373 D-glucosaminide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35373 CHEBI:35372 D-fuconate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35372 CHEBI:35375 alditol 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35375 CHEBI:59345 5,6,7,8-tetrahydrosarcinapterin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59345 CHEBI:35374 D-mannose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35374 UBERON:0002749 regional part of cerebellar cortex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002749 cerebellar cortical segment|segment of cerebellar cortex A regional part of brain that is part of a cerebellar cortex [Automatically generated definition]. CHEBI:74997 mannosyl diphosphorylinositol ceramide(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74997 CHEBI:84317 1-acyl-2-stearoyl-sn-glycero-3-phospho-(1D-myo-inositol) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84317 CHEBI:84315 L-arginyl-L-alpha-amino acid(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84315 CHEBI:84312 dodecanoyl-AMP biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84312 CHEBI:84311 bacilysin zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84311 CHEBI:84310 anticapsin zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84310 CHEBI:35387 L-idarate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35387 CHEBI:142607 alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->4)]-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142607 CHEBI:35389 altrarate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35389 CHEBI:60356 tetraoleyl cardiolipin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60356 CHEBI:59338 methylammonium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59338 CHEBI:35381 monosaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35381 CHEBI:35384 idarate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35384 CHEBI:74994 Man-1-2-Ins-1-P-Cer C(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74994 CHEBI:35386 D-idarate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35386 CHEBI:35385 idarate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35385 CHEBI:11392 2'-(5-triphosphoribosyl)-3'-dephospho-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_11392 CHEBI:50996 tertiary amino compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50996 CHEBI:50995 secondary amino compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50995 CHEBI:50994 primary amino compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50994 CHEBI:50998 trans-2-enoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50998 CHEBI:60362 (KDO)3-lipid IVA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60362 CHEBI:60364 (KDO)-lipid IVA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60364 CHEBI:84322 dapdiamide C zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84322 CHEBI:60365 (KDO)2-lipid IVA(6-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60365 CHEBI:84321 dapdiamide B zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84321 CHEBI:84320 dapdiamide A zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84320 CHEBI:60367 (KDO)3-lipid IVA(7-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60367 CHEBI:35356 dicarboximide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35356 CHEBI:35359 carboxamidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35359 CHEBI:35358 sulfonamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35358 CHEBI:60369 trans,poly-cis-decaprenyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60369 GO:0061900 glial cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061900 A change in morphology and behavior of a glial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. GO:0061902 negative regulation of 1-phosphatidylinositol-3-kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061902 Any process that stops, prevents or reduces the frequency, rate or extent of 1-phosphatidylinositol-3-kinase activity. GO:0061901 regulation of 1-phosphatidylinositol-3-kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061901 Any process that modulates the frequency, rate or extent of 1-phosphatidylinositol-3-kinase activity. GO:0061903 positive regulation of 1-phosphatidylinositol-3-kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061903 Any process that starts or increases the frequency or rate of 1-phosphatidylinositol-3-kinase activity. UBERON:0002743 basal forebrain biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002743 basal forebrain area|pars basalis telencephali A region of the brain consisting of ventral and rostral subcortical regions of the telencephalon, including among others, the basal ganglia, septal nuclei, amygdala, ventral pallidum, substantia innominata, and basal nucleus of Meynert. GO:0061906 autophagosome localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061906 Any process in which an autophagosome is transported to, and/or maintained in, a specific location within the cell. CHEBI:59326 prostaglandin carboxylic acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59326 CHEBI:35350 hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35350 CHEBI:35353 isocyanide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35353 GO:0061908 phagophore biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061908 isolation membrane A disk-like structure that expands, rounds up into a cup-shaped structure, and eventually closes around its cargo (for example cytoplasmic components) to become an autophagosome or Cvt vesicle. GO:0061907 negative regulation of AMPA receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061907 Any process that stops, prevents or reduces the frequency, rate or extent of AMPA glutamate receptor activity. CHEBI:35352 organonitrogen compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35352 UBERON:0002726 cervical spinal cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002726 cervical segments of spinal cord [1-8]|pars cervicalis medullae spinalis|cervical segment of spinal cord|segmenta cervicalia medullae spinalis [1-8|cervical spinal cord A spinal cord segment that adjacent_to a cervical region. CHEBI:60373 lipid IVA oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60373 CHEBI:84335 2-hydroxymyristate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84335 CHEBI:60374 2-cis,6-cis-farnesyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60374 CHEBI:60377 cytidine 5'-monophosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60377 CHEBI:35366 fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35366 CHEBI:84331 N(3)-fumaramoyl-(S)-2,3-diaminopropanoic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84331 CHEBI:35368 hexasaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35368 CHEBI:84330 N(3)-fumaroyl-(S)-2,3-diaminopropanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84330 CHEBI:35367 thiocarboxylic acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35367 CHEBI:35369 pentasaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35369 UBERON:0002731 vestibulocochlear nerve root biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002731 vestibulocochlear nerve roots|statoacoustic nerve fibers|fibrae nervi statoacustici|vestibulocochlear nerve fibers|central part of vestibulocochlear nerve|root of vestibulocochlear nerve|vestibulocochlear nerve tract Either of the two roots that come of the vestibulocochlear nerve CHEBI:50981 secondary aliphatic amine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50981 CHEBI:59314 alpha-D-Galp-(1->4)-beta-D-Galp biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59314 CHEBI:50972 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50972 CHEBI:60384 N-(2,3-dihydroxyhexacosanoyl)-(4R)-hydroxysphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60384 UBERON:0012125 dermatological-muscosal system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012125 dermatological system Anatomical system that consists of the integumental system plus all mucosae and submucosae. CHEBI:84346 cholesteryl all-cis-icosa-8,11,14-trienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84346 CHEBI:49983 3-aminoalaninate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49983 CHEBI:60386 ditrans,polycis-dodecaprenyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60386 CHEBI:60385 ditrans,polycis-tridecaprenyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60385 CHEBI:84345 methyl nogalonate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84345 CHEBI:60388 tri-trans,poly-cis-undecaprenyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60388 CHEBI:35333 4-(4-deoxy-D-gluc-4-enosyluronic acid)-D-galacturonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35333 CHEBI:60387 ditrans,polycis-tetradecaprenyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60387 CHEBI:84342 nogalaviketone(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84342 CHEBI:84341 cholesteryl linolenate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84341 CHEBI:60389 alpha-L-galactose 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60389 GO:0061920 protein propionyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061920 Catalysis of the reaction: propionyl-CoA + lysine in peptide = CoA + N-propionyl-lysine-peptide. CHEBI:35337 central nervous system stimulant biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35337 CHEBI:11369 1L-myo-inositol 1,2,3,4,6-pentakisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_11369 GO:0061922 histone propionyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061922 Catalysis of the reaction: propionyl-CoA + histone = CoA + propionyl-histone. GO:0061921 peptidyl-lysine propionylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061921 The propionylation of peptidyl-lysine. CHEBI:35338 amphetamines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35338 GO:0061924 regulation of formation of radial glial scaffolds biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061924 regulation of radial glial scaffold formation|regulation of Bergmann fiber biosynthesis|regulation of Bergmann fiber formation Any process that modulates the frequency, rate or extent of the formation of radial glial scaffolds. The scaffolds are used as a substrate for the radial migration of cells. GO:0061923 (2S,3R,6S,9S)-(-)-protoillud-7-ene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061923 protoillud-7-ene synthase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + (2S,3R,6S,9S)-(-)-protoillud-7-ene. GO:0061926 positive regulation of formation of radial glial scaffolds biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061926 positive regulation of radial glial scaffold formation|positive regulation of Bergmann fiber formation|positive regulation of Bergmann fiber biosynthesis Any process that increases the frequency, rate or extent of the formation of radial glial cell scaffolds. GO:0061925 negative regulation of formation of radial glial scaffolds biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061925 negative regulation of Bergmann fiber formation|negative regulation of radial glial scaffold formation|negative regulation of Bergmann fiber biosynthesis Any process that reduces the frequency, rate or extent of the formation of radial glial scaffolds. The scaffolds are used as a substrate for the radial migration of cells. GO:0061928 glutathione specific gamma-glutamylcyclotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061928 EC:4.3.2.7|RHEA:47724 Catalysis of the reaction: glutathione = 5-oxoproline + L-cysteinylglycine. GO:0061927 TOC-TIC supercomplex I biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061927 The protein transport macromolecular complex of the chloroplast membrane that interacts with the precursor proteins and contains components of both the outer membrane and inner membrane complexes containing at least Toc75, Toc159, Toc34 and Tic110. CHEBI:35331 rhodopin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35331 GO:0061929 gamma-glutamylaminecyclotransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061929 EC:4.3.2.8|RHEA:16961 Catalysis of the reaction: epsilon-(L-gamma-glutamyl)-L-lysine = L-lysine + 5-oxo-L-proline. CHEBI:35330 spheroidene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35330 GO:0061909 autophagosome-lysosome fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061909 autophagosome-vacuole fusion|autophagosome fusion The process in which autophagosomes, double-membraned vesicles containing cytoplasmic material, fuse with a vacuole (yeast) or lysosome (e.g. mammals and insects). In the case of yeast, inner membrane-bounded structures (autophagic bodies) appear in the vacuole. Fusion provides an acidic environment and digestive function to the interior of the autophagosome. CHEBI:50967 non-covalently-bound molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50967 CHEBI:60390 D-alanyl-D-serine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60390 CHEBI:60392 ditrans,polycis-undecaprenyl phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60392 CHEBI:84359 3-hydroxy-2,4-dioxopentyl phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84359 CHEBI:84358 L-dihydroanticapsin zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84358 CHEBI:84355 3-[(1E,4R)-4-hydroxycyclohex-2-en-1-ylidene]pyruvate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84355 CHEBI:35344 21-hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35344 CHEBI:35343 17beta-hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35343 CHEBI:84354 (4R)-3,4-dihydro-4-hydroxyphenylpyruvate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84354 CHEBI:35346 11beta-hydroxy steroid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35346 CHEBI:35348 3beta-sterol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35348 CHEBI:35347 3alpha-sterol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35347 GO:0061911 amphisome-lysosome fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061911 The process in which amphisomes fuse with a vacuole (yeast) or lysosome (e.g. mammals and insects). In the case of yeast, inner membrane-bounded structures (autophagic bodies) appear in the vacuole. Fusion provides an acidic environment and digestive function to the interior of the amphisome. GO:0061910 autophagosome-endosome fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061910 The process in which an autophagosome fuses with an endosome to create an intermediate autophagic organelle called amphisome. CHEBI:35349 7beta-hydroxy steroid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35349 GO:0061913 positive regulation of growth plate cartilage chondrocyte proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061913 Any process that increases the rate, frequency, or extent of the multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population. GO:0061912 selective autophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061912 The macroautophagy process in which specific structures are targeted by the autophagy process. GO:0061915 actin fusion focus localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061915 actin fusion focus localisation Any process in which an actin fusion focus are transported to, or maintained in, a specific location. The actin fusion focus is an aster-like, F-actin-containing structure at the mating projection tip where the cell wall is degraded during conjugation with cellular fusion. GO:0061914 negative regulation of growth plate cartilage chondrocyte proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061914 Any process that decreases the rate, frequency, or extent of the multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population. GO:0061917 leading edge of dendritic growth cone biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061917 dendritic growth cone leading edge|distal tip of dendritic growth cone That part of the dendritic growth cone which represents the distal part of the structure. CHEBI:35340 methamphetamine hydrochloride biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35340 GO:0061916 leading edge of axonal growth cone biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061916 axonal growth cone leading edge|distal tip of axonal growth cone That part of the axonal growth cone which represents the distal part of the structure. GO:0061919 process utilizing autophagic mechanism biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0061919 A cellular process involving delivery of a portion of the cytoplasm to lysosomes or to the plant or fungal vacuole that does not involve direct transport through the endocytic or vacuolar protein sorting (Vps) pathways. This process typically leads to degradation of the cargo; however, it can also be used to deliver resident proteins, such as in the cytoplasm-to-vacuole targeting (Cvt) pathway. CHEBI:35342 17alpha-hydroxy steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35342 CHEBI:35341 steroid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35341 CHEBI:50956 organoarsonic acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50956 CHEBI:50955 arsonic acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50955 CHEBI:25998 3-phenyllactic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25998 GO:0046305 alkanesulfonate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046305 alkanesulfonate formation|alkanesulfonate biosynthesis|alkanesulphonate biosynthesis|alkanesulphonate biosynthetic process|alkanesulfonate anabolism|alkanesulfonate synthesis The chemical reactions and pathways resulting in the formation of alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group. GO:0046304 2-nitropropane catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046304 2-nitropropane degradation|2-nitropropane breakdown|2-nitropropane catabolism The chemical reactions and pathways resulting in the breakdown of 2-nitropropane, a clear, colorless liquid with a mild, fruity odor. CHEBI:35318 glycosylmannose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35318 GO:0046303 obsolete 2-nitropropane biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046303 2-nitropropane synthesis|2-nitropropane formation|2-nitropropane biosynthetic process|2-nitropropane anabolism|2-nitropropane biosynthesis OBSOLETE. The chemical reactions and pathways resulting in the formation of 2-nitropropane, a clear, colorless liquid with a mild, fruity odor. GO:0046302 2-chloro-N-isopropylacetanilide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046302 2-chloro-N-isopropylacetanilide degradation|2-chloro-N-isopropylacetanilide breakdown|2-chloro-N-isopropylacetanilide catabolism The chemical reactions and pathways resulting in the breakdown of 2-chloro-N-isopropylacetanilide, an acylanide herbicide widely used to protect corn, onion, cabbage, rose bushes, and ornamental plants. GO:0046301 obsolete 2-chloro-N-isopropylacetanilide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046301 2-chloro-N-isopropylacetanilide synthesis|2-chloro-N-isopropylacetanilide formation|2-chloro-N-isopropylacetanilide biosynthetic process|2-chloro-N-isopropylacetanilide anabolism|2-chloro-N-isopropylacetanilide biosynthesis OBSOLETE. The chemical reactions and pathways resulting in the formation of 2-chloro-N-isopropylacetanilide, an acylanide herbicide widely used to protect corn, onion, cabbage, rose bushes, and ornamental plants. GO:0046300 2,4-dichlorophenoxyacetic acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046300 2,4-dichlorophenoxyacetic acid degradation|2,4-dichlorophenoxyacetic acid breakdown|2,4-dichlorophenoxyacetic acid catabolism The chemical reactions and pathways resulting in the breakdown of 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds. CHEBI:25990 phenylethanolamines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25990 CHEBI:35311 carotenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35311 CHEBI:35310 carotenone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35310 CHEBI:35313 hexoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35313 GO:0061940 regulation of c-di-GMP signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061940 Any process that modulates the rate frequency or extent of c-di-GMP signaling. CHEBI:35312 pentoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35312 CHEBI:84363 acarbose(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84363 GO:0046309 1,3-dichloro-2-propanol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046309 1,3-dichloro-2-propanol anabolism|1,3-dichloro-2-propanol synthesis|1,3-dichloro-2-propanol formation|1,3-dichloro-2-propanol biosynthesis The chemical reactions and pathways resulting in the formation of 1,3-dichloro-2-propanol (DCP), a halohydrin suspected of being carcinogenic, mutagenic and genotoxic. GO:0061942 negative regulation of c-di-GMP signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061942 Any process that decreases the rate, frequency or extent of c-di-GMP signaling. CHEBI:35315 deoxy hexoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35315 CHEBI:84362 2-epi-5-epi-valiolone 7-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84362 GO:0046308 Z-phenylacetaldoxime catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046308 Z-phenylacetaldoxime degradation|Z-phenylacetaldoxime breakdown|Z-phenylacetaldoxime catabolism The chemical reactions and pathways resulting in the breakdown of Z-phenylacetaldoxime, a member of the glucosinolate group of compounds. GO:0061941 positive regulation of c-di-GMP signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061941 Any process that increases the rate, frequency or extent of c-di-GMP signaling. CHEBI:35314 glycosiduronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35314 CHEBI:84361 5-epi-valiolone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84361 GO:0046307 Z-phenylacetaldoxime biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046307 Z-phenylacetaldoxime anabolism|Z-phenylacetaldoxime synthesis|Z-phenylacetaldoxime formation|Z-phenylacetaldoxime biosynthesis The chemical reactions and pathways resulting in the formation of Z-phenylacetaldoxime, a member of the glucosinolate group of compounds. GO:0061944 negative regulation of protein K48-linked ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061944 Any process that stops, prevents or reduces the frequency, rate or extent of K48-linked ubiquitination, a protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation. CHEBI:35317 glycosylgalactose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35317 GO:0046306 alkanesulfonate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046306 alkanesulfonate catabolism|alkanesulphonate catabolic process|alkanesulphonate catabolism|alkanesulfonate degradation|alkanesulfonate breakdown The chemical reactions and pathways resulting in the breakdown of alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group. UBERON:0002786 root of abducens nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002786 root of abducens nerve|central part of abducens nerve|abducens nerve/root|abducens nerve fibers|fibrae nervi abducentis|abducens nerve root|abducens nerve tract Nerve fibers arising from motor neurons in the abducens nucleus that are contained within the pontine tegmentum GO:0061945 regulation of protein K48-linked ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061945 Any process that modulates the rate, frequency or extent of protein K-48-linked ubiquitination, a protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation. GO:0061948 premature acrosome loss biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061948 spontaneous acrosome loss The discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents. UBERON:0002787 decussation of trochlear nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002787 decussation of the trochlear nerve|decussation of trochlear nerve fibers|trochlear nerve decussation|trochlear neural decussation|trochlear decussation|decussatio fibrarum nervorum trochlearium|decussation of trochlear nerve (IV)|decussatio nervorum trochlearium|decussatio trochlearis the crossing of the two trochlear nerves at their exit through the velum medullare anterius. GO:0061949 regulation of premature acrosome loss biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061949 Any process that modulates the rate, frequency or extent of the discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents. UBERON:0002768 vestibulospinal tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002768 tractus vestibulospinalis|vestibulo-spinal tracts|vestibulospinal pathway|vestibulo-spinal tract|vestibulospinal tracts A long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the vestibular nucleus of the pons towards target cells in the spinal cord[GO]. UBERON:0002769 superior temporal gyrus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002769 gyrus temporalis superior|gyrus temporalis superior Component of the temporal lobe, lateral aspect. The rostral boundary is the rostral extent of the ssuperior temporal sulcus. The caudal boundary is the cauday portion of the superior temporal gyrus (posterior to becoming continuous with the supramarginal gyrus). The medial boundary is the lateral fissure (and when present the supramarginal gyrus), and the lateral boundary is the superior temporal suclus (Christine Fennema-Notestine). GO:0046316 gluconokinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046316 KEGG_REACTION:R01737|EC:2.7.1.12|RHEA:19433|MetaCyc:GLUCONOKIN-RXN gluconate kinase activity|gluconokinase (phosphorylating)|ATP:D-gluconate 6-phosphotransferase activity Catalysis of the reaction: D-gluconate + ATP = 6-phospho-D-gluconate + ADP + 2 H(+). CHEBI:50949 serotonin uptake inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50949 GO:0046315 phosphocreatine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046315 phosphocreatine catabolism|phosphocreatine degradation|phosphocreatine breakdown The chemical reactions and pathways resulting in the breakdown of phosphocreatine, a phosphagen of creatine which is synthesized and broken down by creatine phosphokinase. CHEBI:35329 carotenoid ether biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35329 CHEBI:50948 (2S,3S)-2-methylcitric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50948 GO:0046314 phosphocreatine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046314 phosphocreatine biosynthesis|phosphocreatine anabolism|phosphocreatine synthesis|phosphocreatine formation The chemical reactions and pathways resulting in the formation of phosphocreatine, a phosphagen of creatine which is synthesized and broken down by creatine phosphokinase. GO:0046313 phosphoarginine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046313 phosphoarginine catabolism|phosphoarginine degradation|phosphoarginine breakdown The chemical reactions and pathways resulting in the breakdown of phosphoarginine, a phosphorylated derivative of the amino acid arginine. GO:0046312 phosphoarginine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046312 phosphoarginine anabolism|phosphoarginine synthesis|phosphoarginine formation|phosphoarginine biosynthesis The chemical reactions and pathways resulting in the formation of phosphoarginine, a phosphorylated derivative of the amino acid arginine. GO:0046311 prenylcysteine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046311 prenylcysteine biosynthesis|prenylcysteine anabolism|prenylcysteine synthesis|prenylcysteine formation The chemical reactions and pathways resulting in the formation of prenylcysteine, 3-methyl-2-buten-1-yl-cysteine, a derivative of the amino acid cysteine formed by the covalent addition of a prenyl residue. GO:0046310 1,3-dichloro-2-propanol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046310 1,3-dichloro-2-propanol degradation|1,3-dichloro-2-propanol catabolism|1,3-dichloro-2-propanol breakdown The chemical reactions and pathways resulting in the breakdown of 1,3-dichloro-2-propanol (DCP), a halohydrin suspected of being carcinogenic, mutagenic and genotoxic. CHEBI:35324 hydrazinium(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35324 CHEBI:84374 3-ammonio-L-alanine(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84374 CHEBI:35323 N-substituted amine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35323 GO:0061931 positive regulation of erythrocyte enucleation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061931 Any process that increases the frequency, rate or extent of erythrocyte enucleation. GO:0061930 regulation of erythrocyte enucleation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061930 Any process that modulates the frequency, rate or extent of erythrocyte enucleation. GO:0046319 positive regulation of glucosylceramide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046319 up regulation of glucosylceramide biosynthetic process|activation of glucosylceramide biosynthetic process|positive regulation of glucosylceramide biosynthesis|stimulation of glucosylceramide biosynthetic process|up-regulation of glucosylceramide biosynthetic process|positive regulation of glucosylceramide anabolism|upregulation of glucosylceramide biosynthetic process|positive regulation of glucosylceramide synthesis|positive regulation of glucosylceramide formation Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosylceramide. CHEBI:35325 hydrazinium(2+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35325 GO:0046318 negative regulation of glucosylceramide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046318 downregulation of glucosylceramide biosynthetic process|down-regulation of glucosylceramide biosynthetic process|negative regulation of glucosylceramide biosynthesis|inhibition of glucosylceramide biosynthetic process|negative regulation of glucosylceramide anabolism|negative regulation of glucosylceramide synthesis|negative regulation of glucosylceramide formation|down regulation of glucosylceramide biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosylceramide. CHEBI:35328 spirilloxanthin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35328 GO:0046317 regulation of glucosylceramide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046317 regulation of glucosylceramide synthesis|regulation of glucosylceramide formation|regulation of glucosylceramide anabolism|regulation of glucosylceramide biosynthesis Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosylceramide. GO:0061932 negative regulation of erythrocyte enucleation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061932 Any process that decreases the frequency, rate or extent of erythrocyte enucleation. GO:0061935 fusion of sperm to egg plasma membrane involved in double fertilization forming two zygotes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061935 The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of double fertilization forming two zygotes. GO:0061934 regulation of adenine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061934 Any process that modulates the frequency, rate or extent of an adenine biosynthetic process. GO:0061936 fusion of sperm to egg plasma membrane involved in double fertilization forming a zygote and endosperm biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061936 The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of double fertilization forming a zygote and endosperm. UBERON:0002776 ventral nuclear group biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002776 ventral nuclear group of thalamus|ventral nuclei of thalamus|ventral dorsal thalamic nuclear group|ventral thalamus nucleus|ventral group of the dorsal thalamus|ventral nuclear group|ventral tier thalamic nuclei|nuclei ventrales thalami|ventral nuclear mass|VNG|ventral group of dorsal thalamus|dorsal thalamus, ventral group Nuclei in the ventral part of the thalamus, involved in modulating activity of dorsal thalamic nuclei. GO:0061939 c-di-GMP signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061939 cyclic diguanylate signaling|cyclic di-GMP signaling|cyclic di-(3':5')-guanosine monophosphate signaling|3',5'-cyclic di-GMP signaling Any process that mediates the transfer of information from one cell to another using c-di-GMP as the signal. UBERON:0002770 posterior hypothalamic region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002770 posterior hypothalamus|mammillary level of hypothalamus|hypothalamus posterior|PHR|mammillary region|regio hypothalamica posterior The part of the hypothalamus posterior to the middle region consisting of several nuclei including the medial mamillary nucleus, lateral mamillary nucleus, and posterior hypothalamic nucleus (posterior hypothalamic area). The posterior hypothalamic area is concerned with control of sympathetic responses and is sensitive to conditions of decreasing temperature and controls the mechanisms for the conservation and increased production of heat. GO:0061938 protein localization to somatodendritic compartment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061938 somatodendritic protein localization A process in which a protein is transported to or maintained in a location within the somatodendritic compartment. CHEBI:74901 1-oleoyl-2-palmitoleoyl-sn-glycero-3-phospho-L-serine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74901 CHEBI:74900 N(4)-acetylcytidine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74900 CHEBI:74903 isocaproic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74903 CHEBI:74902 1-oleoyl-2-stearoyl-sn-glycero-3-phospho-L-serine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74902 CHEBI:74905 1,2-dioleoyl-sn-glycero-3-phospho-L-serine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74905 CHEBI:74904 isocaproate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74904 CHEBI:74909 1-oleoyl-2-palmitoyl-sn-glycero-3-phospho-L-serine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74909 GO:1900198 positive regulation of penicillin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900198 upregulation of penicillin synthesis|upregulation of penicillin formation|up regulation of penicillin biosynthesis|up regulation of penicillin biosynthetic process|up-regulation of penicillin anabolism|activation of penicillin biosynthetic process|positive regulation of penicillin biosynthesis|up-regulation of penicillin synthesis|activation of penicillin biosynthesis|activation of penicillin anabolism|up-regulation of penicillin formation|activation of penicillin synthesis|positive regulation of penicillin anabolism|up-regulation of penicillin biosynthesis|up-regulation of penicillin biosynthetic process|activation of penicillin formation|up regulation of penicillin anabolism|positive regulation of penicillin synthesis|up regulation of penicillin synthesis|positive regulation of penicillin formation|up regulation of penicillin formation|upregulation of penicillin biosynthetic process|upregulation of penicillin biosynthesis|upregulation of penicillin anabolism Any process that activates or increases the frequency, rate or extent of penicillin biosynthetic process. GO:1900197 negative regulation of penicillin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900197 inhibition of penicillin anabolism|down regulation of penicillin formation|downregulation of penicillin biosynthetic process|downregulation of penicillin biosynthesis|inhibition of penicillin synthesis|inhibition of penicillin formation|negative regulation of penicillin biosynthesis|down-regulation of penicillin biosynthesis|down-regulation of penicillin biosynthetic process|negative regulation of penicillin anabolism|down-regulation of penicillin anabolism|negative regulation of penicillin synthesis|down-regulation of penicillin synthesis|inhibition of penicillin biosynthetic process|negative regulation of penicillin formation|down-regulation of penicillin formation|downregulation of penicillin anabolism|inhibition of penicillin biosynthesis|down regulation of penicillin anabolism|downregulation of penicillin synthesis|downregulation of penicillin formation|down regulation of penicillin synthesis|down regulation of penicillin biosynthesis|down regulation of penicillin biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of penicillin biosynthetic process. GO:1900199 positive regulation of protein export from nucleus during meiotic anaphase II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900199 positive regulation of protein export from nucleus involved in meiotic anaphase II Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm, during anaphase occurring as part of meiosis II. CHEBI:74917 1-acyl-2-oleoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74917 CHEBI:74920 1-acyl-2-linoleoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74920 CHEBI:74922 1-acyl-2-arachidonoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74922 CHEBI:74925 EC 3.4.23.46 (memapsin 2) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74925 CHEBI:74924 aclacinomycin N(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74924 CHEBI:74929 aclacinomycin Y(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74929 CHEBI:74928 1-oleoyl-2-arachidonoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74928 CHEBI:74930 1-oleoyl-2-myristoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74930 CHEBI:74931 tetracenomycin F1(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74931 CHEBI:74934 tetracenomycin D3(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74934 CHEBI:74933 1-(gamma-linolenoyl)-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74933 CHEBI:74936 1-(gamma-linolenoyl)-2-oleoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74936 CHEBI:74938 1-arachidonoyl-sn-glycerol 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74938 CHEBI:74937 1-oleoyl-2-icosanoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74937 CHEBI:74939 1-icosanoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74939 CHEBI:59399 glutathione amide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59399 CHEBI:74941 1-arachidonoyl-2-oleoyl-sn-glycero-3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74941 CHEBI:74943 1-myristoyl-2-oleoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74943 CHEBI:74942 1-icosanoyl-2-oleoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74942 CHEBI:74945 1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate(14-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74945 CHEBI:74946 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate(13-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74946 UBERON:0002714 rubrospinal tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002714 tractus rubrospinalis|Monakow's tract|rubrospinal tract (Monakow) White matter tract arising in red nucleus and projecting to spinal cord ventral horn CHEBI:74949 EC 3.1.27.3 (ribonuclease T1) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74949 CHEBI:74948 guanosine 2'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74948 CHEBI:60302 L-thyroxine(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60302 CHEBI:59386 2-O-(alpha-D-mannopyranosyl)-1-phosphatidyl-1D-myo-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59386 CHEBI:60308 3,3',5-triiodo-L-thyroninate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60308 UBERON:0002722 trochlear nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002722 fourth cranial nerve nucleus|nucleus of trochlear nerve|nucleus nervi trochlearis|trochlear motor nucleus|nucleus nervi trochlearis|motor nucleus IV|trochlear IV nucleus|nIV Nucleus in the midbrain at the level of the inferior colliculus near the midline, containing the motor neurons giving rise to the trochlear nerve, innervating the contralateral superior oblique extraocular muscle of the eye (Brodal, Neurological Anatomy, 3rd ed, 1981, pg. 533). CHEBI:74951 cysteamine S-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74951 UBERON:0002707 corticospinal tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002707 fibrae corticospinales|tractus pyramidalis|pyramid (Willis)|corticospinal fibers|tractus corticospinalis|tractus cortico-spinalis|pyramidal tract|fasciculus cerebro-spinalis|fasciculus pyramidalis The corticospinal fibers that arise from the pyramidal cells within the cerebral cortex layer V of the precentral motor area, the premotor area and the postcentral gyrus, then descend into and through the medulla to form the lateral corticospinal tract and the anterior corticospinal tract. CHEBI:74956 O(4)-phosphotyrosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74956 CHEBI:74955 O(4)-phosphonatotyrosine(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74955 CHEBI:74958 N-isovaleryl-L-homoserine lactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74958 UBERON:0002704 metathalamus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002704 geniculate thalamic nuclear group (metathalamus)|MTh|geniculate group of dorsal thalamus|corpora geniculata|geniculate thalamic group|nuclei metathalami|geniculate group of the dorsal thalamus The metathalamus is a composite structure of the thalamus, consisting of the medial geniculate nucleus and the lateral geniculate nucleus. [WP,unvetted]. CHEBI:74959 O(4)-phospho-D-tyrosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74959 CHEBI:60311 thyroid hormone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60311 CHEBI:60312 2-amino-2-deoxy-D-galactopyranose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60312 CHEBI:60319 1-O-palmitoyl-2-O-(5-oxovaleryl)-sn-glycero-3-phosphocholine(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60319 UBERON_CORE:layer_part_of layer part of biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/uberon/core#layer_part_of layer_part_of CHEBI:74950 organic phosphorothioate anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74950 CHEBI:74963 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74963 CHEBI:74965 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74965 CHEBI:74967 1-lauroyl-2-arachidonoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74967 CHEBI:74966 1-lauroyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74966 CHEBI:74969 mucilage biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74969 CHEBI:74968 1-icosanoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74968 CHEBI:35399 D-tartrate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35399 CHEBI:35398 L-tartrate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35398 CHEBI:142638 nectriapyrones biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_142638 CHEBI:59360 hexacarboxylic acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59360 CHEBI:60327 ganglioside GM2 (18:0) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60327 CHEBI:35391 aspartate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35391 CHEBI:35390 galactarate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35390 CHEBI:35392 glucarate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35392 CHEBI:74961 raffinose family oligosaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74961 CHEBI:35397 tartrate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35397 CHEBI:74974 N-(4-coumaroyl)-L-homoserine lactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74974 CHEBI:74975 1-oleoyl-2-arachidonoyl-sn-glycerol-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74975 CHEBI:74978 ginsenoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74978 CHEBI:74977 1-oleoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74977 CHEBI:142622 primary fatty alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142622 CHEBI:142621 medium-chain fatty aldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142621 CHEBI:60331 2-O-(6-phospho-alpha-D-mannosyl)-D-glycerate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60331 CHEBI:60332 alpha-D-mannose 6-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60332 CHEBI:59354 (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59354 CHEBI:59353 (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59353 CHEBI:60334 peptide anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60334 CHEBI:59352 chromenemonocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59352 CHEBI:142626 alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->4)]-[alpha-N-acetylneuraminosyl-(2->6)]-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142626 CHEBI:59350 2-hydroxychromene-2-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59350 CHEBI:74970 1-icosanoyl-2-arachidonoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74970 CHEBI:59359 hexacarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59359 CHEBI:74972 (11Z,14Z,17Z,20Z,23Z)-3-oxohexacosapentaenoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74972 CHEBI:74971 1-oleoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74971 CHEBI:59356 7-(3-methylbut-2-enyl)-L-tryptophan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59356 GO:0071242 cellular response to ammonium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071242 cellular response to ammonia Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus. GO:0046286 flavonoid phytoalexin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046286 flavonoid phytoalexin catabolism|flavonoid phytoalexin degradation|flavonoid phytoalexin breakdown The chemical reactions and pathways resulting in the breakdown of flavonoid phytoalexins, a group of water-soluble phenolic derivatives containing a flavan skeleton, which possess antibiotic activity and are produced by plant tissues in response to infection. GO:0046285 flavonoid phytoalexin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046285 flavonoid phytoalexin metabolism The chemical reactions and pathways involving flavonoid phytoalexins, a group of water-soluble phenolic derivatives containing a flavan skeleton, which possess antibiotic activity and are produced by plant tissues in response to infection. GO:0071241 cellular response to inorganic substance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071241 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus. GO:0071240 cellular response to food biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071240 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat. GO:0046284 anthocyanin-containing compound catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046284 anthocyanin degradation|anthocyanin catabolism|anthocyanin breakdown|anthocyanin catabolic process The chemical reactions and pathways resulting in the breakdown of anthocyanins, any member of a group of intensely colored soluble glycosides of anthocyanidins. GO:0046283 anthocyanin-containing compound metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046283 anthocyanin metabolic process|anthocyanin metabolism The chemical reactions and pathways involving anthocyanins, any member of a group of intensely colored soluble glycosides of anthocyanidins that occur in plants. They are responsible from most of the scarlet, purple, mauve and blue coloring in higher plants, especially of flowers. GO:0046282 cinnamic acid ester catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046282 cinnamic acid ester catabolism|cinnamic acid ester degradation|cinnamic acid ester breakdown The chemical reactions and pathways resulting in the breakdown of ester derivatives of cinnamic acid, phenylpropenoic acid. GO:1900118 negative regulation of execution phase of apoptosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900118 downregulation of execution phase of apoptosis|down regulation of execution phase of apoptosis|inhibition of execution phase of apoptosis|down-regulation of execution phase of apoptosis Any process that stops, prevents or reduces the frequency, rate or extent of execution phase of apoptosis. GO:1900117 regulation of execution phase of apoptosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900117 Any process that modulates the frequency, rate or extent of execution phase of apoptosis. GO:0046281 cinnamic acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046281 cinnamic acid catabolism|phenylacrylic acid catabolism|cinnamylic acid catabolic process|cinnamic acid degradation|cinnamic acid breakdown|cinnamylic acid catabolism|phenylacrylic acid catabolic process The chemical reactions and pathways resulting in the breakdown of cinnamic acid, 3-phenyl-2-propenoic acid. GO:0046280 chalcone catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046280 chalcone catabolism|chalcone degradation|chalcone breakdown The chemical reactions and pathways resulting in the breakdown of chalcone, phenyl steryl ketone or its hydroxylated derivatives. GO:1900119 positive regulation of execution phase of apoptosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900119 upregulation of execution phase of apoptosis|up-regulation of execution phase of apoptosis|activation of execution phase of apoptosis|up regulation of execution phase of apoptosis Any process that activates or increases the frequency, rate or extent of execution phase of apoptosis. GO:1900114 positive regulation of histone H3-K9 trimethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900114 upregulation of histone H3-K9 trimethylation|up-regulation of histone H3-K9 trimethylation|activation of histone H3-K9 trimethylation|up regulation of histone H3-K9 trimethylation Any process that activates or increases the frequency, rate or extent of histone H3-K9 trimethylation. GO:1900113 negative regulation of histone H3-K9 trimethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900113 down regulation of histone H3-K9 trimethylation|inhibition of histone H3-K9 trimethylation|down-regulation of histone H3-K9 trimethylation|downregulation of histone H3-K9 trimethylation Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K9 trimethylation. GO:1900116 extracellular negative regulation of signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900116 inhibition of signal transduction in extracellular region|negative regulation of signalling pathway in extracellular region|negative regulation of signaling pathway in extracellular region|down regulation of signal transduction in extracellular region|extracellular inhibition of signaling pathway|downregulation of signal transduction in extracellular region|down-regulation of signal transduction in extracellular region Any negative regulation of signal transduction that takes place in extracellular region. GO:1900115 extracellular regulation of signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900115 regulation of signaling pathway in extracellular region|regulation of signalling pathway in extracellular region Any regulation of signal transduction that takes place in the extracellular region. GO:1900110 negative regulation of histone H3-K9 dimethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900110 negative regulation of histone lysine H3 K9 dimethylation|down-regulation of histone lysine H3 K9 dimethylation|down-regulation of histone H3-K9 dimethylation|down regulation of histone H3 K9 dimethylation|downregulation of histone H3 K9 dimethylation|inhibition of histone H3-K9 dimethylation|downregulation of histone lysine H3 K9 dimethylation|down regulation of histone lysine H3 K9 dimethylation|negative regulation of histone H3 K9 dimethylation|down-regulation of histone H3 K9 dimethylation|inhibition of histone lysine H3 K9 dimethylation|down regulation of histone H3-K9 dimethylation|inhibition of histone H3 K9 dimethylation|downregulation of histone H3-K9 dimethylation Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K9 dimethylation. GO:0046289 isoflavonoid phytoalexin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046289 isoflavonoid phytoalexin metabolism The chemical reactions and pathways involving isoflavonoid phytoalexins, a group of water-soluble phenolic derivatives isomeric with flavonoids that possess antibiotic activity and are produced by plant tissues in response to infection. GO:0046288 isoflavonoid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046288 isoflavonoid breakdown|isoflavonoid catabolism|isoflavonoid degradation The chemical reactions and pathways resulting in the breakdown of isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids. GO:1900112 regulation of histone H3-K9 trimethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900112 Any process that modulates the frequency, rate or extent of histone H3-K9 trimethylation. GO:1900111 positive regulation of histone H3-K9 dimethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900111 upregulation of histone H3 K9 dimethylation|positive regulation of histone lysine H3 K9 dimethylation|up regulation of histone lysine H3 K9 dimethylation|up-regulation of histone H3-K9 dimethylation|up regulation of histone H3 K9 dimethylation|activation of histone H3 K9 dimethylation|positive regulation of histone H3 K9 dimethylation|upregulation of histone lysine H3 K9 dimethylation|upregulation of histone H3-K9 dimethylation|up-regulation of histone H3 K9 dimethylation|activation of histone lysine H3 K9 dimethylation|up-regulation of histone lysine H3 K9 dimethylation|up regulation of histone H3-K9 dimethylation|activation of histone H3-K9 dimethylation Any process that activates or increases the frequency, rate or extent of histone H3-K9 dimethylation. GO:0046287 isoflavonoid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046287 isoflavonoid metabolism The chemical reactions and pathways involving isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids, containing a flavan skeleton. They are differentiated from flavonoids by the point of attachment of the aromatic ring group. GO:0071249 cellular response to nitrate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071249 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrate stimulus. GO:0071248 cellular response to metal ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071248 cellular response to heavy metal|cellular response to metal Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus. GO:0071247 cellular response to chromate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071247 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chromate stimulus. GO:0071246 cellular response to chlorate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071246 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chlorate stimulus. GO:0071245 cellular response to carbon monoxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071245 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon monoxide (CO) stimulus. GO:0071244 cellular response to carbon dioxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071244 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus. GO:0071243 cellular response to arsenic-containing substance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071243 cellular response to arsenic Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides. GO:0046297 obsolete 2,4-dichlorobenzoate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046297 2,4-dichlorobenzoate anabolism|2,4-dichlorobenzoate synthesis|2,4-dichlorobenzoate formation|2,4-dichlorobenzoate biosynthetic process|2,4-dichlorobenzoate biosynthesis OBSOLETE. The chemical reactions and pathways resulting in the formation of 2,4-dichlorobenzoate, a chlorinated aromatic compound which is a key intermediate in the aerobic degradation of polychlorinated biphenyls (PCBs). GO:0071231 cellular response to folic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071231 response to vitamin B9|response to folate Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a folic acid stimulus. GO:0071230 cellular response to amino acid stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071230 cellular response to amino acid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups. GO:0046296 glycolate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046296 glycolate degradation|glycolate catabolism|glycolate breakdown The chemical reactions and pathways resulting in the breakdown of glycolate, the anion of hydroxyethanoic acid (glycolic acid). GO:0046295 glycolate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046295 glycolate synthesis|glycolate formation|glycolate biosynthesis|glycolate anabolism The chemical reactions and pathways resulting in the formation of glycolate, the anion of hydroxyethanoic acid (glycolic acid). GO:0046294 formaldehyde catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046294 formaldehyde catabolism|methanal catabolism|formaldehyde degradation|formaldehyde breakdown|methanal catabolic process The chemical reactions and pathways resulting in the breakdown of formaldehyde (methanal, H2C=O), the simplest aldehyde. GO:1900129 positive regulation of G-protein activated inward rectifier potassium channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900129 upregulation of G protein enhanced inward rectifier potassium channel activity|up regulation of G-protein activated inward rectifier potassium channel activity|up-regulation of G protein activated inward rectifier potassium channel activity|activation of G-protein activated inward rectifier potassium channel activity|upregulation of G-protein-enhanced inward rectifier potassium channel activity|positive regulation of G-protein enhanced inward rectifier potassium channel activity|upregulation of G-protein-activated inward rectifier potassium channel activity|up-regulation of G protein enhanced inward rectifier potassium channel activity|up regulation of G-protein enhanced inward rectifier potassium channel activity|activation of G protein enhanced inward rectifier potassium channel activity|upregulation of G protein activated inward rectifier potassium channel activity|up-regulation of G-protein-enhanced inward rectifier potassium channel activity|activation of G-protein-enhanced inward rectifier potassium channel activity|up regulation of G-protein-activated inward rectifier potassium channel activity|up-regulation of G-protein activated inward rectifier potassium channel activity|activation of G-protein-activated inward rectifier potassium channel activity|upregulation of G-protein enhanced inward rectifier potassium channel activity|positive regulation of G-protein-activated inward rectifier potassium channel activity|positive regulation of G protein enhanced inward rectifier potassium channel activity|up regulation of G protein enhanced inward rectifier potassium channel activity|up regulation of G protein activated inward rectifier potassium channel activity|activation of G protein activated inward rectifier potassium channel activity|positive regulation of G protein activated inward rectifier potassium channel activity|upregulation of G-protein activated inward rectifier potassium channel activity|positive regulation of G-protein-enhanced inward rectifier potassium channel activity|up regulation of G-protein-enhanced inward rectifier potassium channel activity|up-regulation of G-protein enhanced inward rectifier potassium channel activity|activation of G-protein enhanced inward rectifier potassium channel activity|up-regulation of G-protein-activated inward rectifier potassium channel activity Any process that activates or increases the frequency, rate or extent of G-protein activated inward rectifier potassium channel activity. GO:0046293 formaldehyde biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046293 formaldehyde anabolism|formaldehyde synthesis|formaldehyde formation|formaldehyde biosynthesis|methanal biosynthetic process|methanal biosynthesis The chemical reactions and pathways resulting in the formation of formaldehyde (methanal, H2C=O), the simplest aldehyde. CHEBI:25901 pentose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25901 GO:1900128 regulation of G-protein activated inward rectifier potassium channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900128 regulation of G-protein-enhanced inward rectifier potassium channel activity|regulation of G-protein-activated inward rectifier potassium channel activity|regulation of G-protein enhanced inward rectifier potassium channel activity|regulation of G protein activated inward rectifier potassium channel activity|regulation of G protein enhanced inward rectifier potassium channel activity Any process that modulates the frequency, rate or extent of G-protein activated inward rectifier potassium channel activity. GO:0046292 formaldehyde metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046292 formaldehyde metabolism|methanal metabolic process|methanal metabolism The chemical reactions and pathways involving formaldehyde (methanal, H2C=O), a colorless liquid or gas with a pungent odor, commonly used as a fixative or an antibacterial agent. CHEBI:25900 aldopentose phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25900 GO:0046291 obsolete 6-hydroxycineole biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046291 6-endo-hydroxycineole biosynthesis|6-endo-hydroxycineole biosynthetic process|6-hydroxycineole anabolism|6-hydroxycineole synthesis|6-hydroxycineole formation|hydroxycineol biosynthesis|hydroxycineol biosynthetic process|6-hydroxycineole biosynthesis|6-hydroxycineole biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of 6-hydroxycineole (6-hydroxy-1,8-epoxy-p-menthane), a hydrocarbon with the formula C10H18O2. GO:0046290 isoflavonoid phytoalexin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046290 isoflavonoid phytoalexin degradation|isoflavonoid phytoalexin breakdown|isoflavonoid phytoalexin catabolism The chemical reactions and pathways resulting in the breakdown of isoflavonoid phytoalexins, a group of water-soluble phenolic derivatives isomeric with flavonoids that possess antibiotic activity and are produced by plant tissues in response to infection. GO:1900125 regulation of hyaluronan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900125 regulation of hyaluronan biosynthesis|regulation of hyaluronan anabolism|regulation of hyaluronan synthesis|regulation of hyaluronan formation Any process that modulates the frequency, rate or extent of hyaluronan biosynthetic process. GO:1900124 negative regulation of nodal receptor complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900124 inhibition of ActRIIB.ALK4.EGF-CFC complex formation|down regulation of nodal receptor complex assembly|downregulation of nodal receptor complex assembly|down-regulation of nodal receptor complex formation|negative regulation of nodal receptor complex formation|down-regulation of nodal receptor complex assembly|down-regulation of ActRIIB.ALK4.EGF-CFC complex formation|negative regulation of ActRIIB.ALK4.EGF-CFC complex formation|downregulation of nodal receptor complex formation|inhibition of nodal receptor complex assembly|down regulation of nodal receptor complex formation|downregulation of ActRIIB.ALK4.EGF-CFC complex formation|inhibition of nodal receptor complex formation|down regulation of ActRIIB.ALK4.EGF-CFC complex formation Any process that stops, prevents or reduces the frequency, rate or extent of nodal receptor complex assembly. GO:1900127 positive regulation of hyaluronan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900127 upregulation of hyaluronan biosynthesis|upregulation of hyaluronan biosynthetic process|activation of hyaluronan synthesis|positive regulation of hyaluronan anabolism|activation of hyaluronan formation|up regulation of hyaluronan anabolism|positive regulation of hyaluronan synthesis|up regulation of hyaluronan synthesis|positive regulation of hyaluronan formation|up regulation of hyaluronan biosynthetic process|up regulation of hyaluronan biosynthesis|up regulation of hyaluronan formation|positive regulation of hyaluronan biosynthesis|activation of hyaluronan biosynthetic process|upregulation of hyaluronan anabolism|activation of hyaluronan biosynthesis|upregulation of hyaluronan synthesis|upregulation of hyaluronan formation|up-regulation of hyaluronan anabolism|up-regulation of hyaluronan biosynthesis|up-regulation of hyaluronan biosynthetic process|up-regulation of hyaluronan synthesis|activation of hyaluronan anabolism|up-regulation of hyaluronan formation Any process that activates or increases the frequency, rate or extent of hyaluronan biosynthetic process. GO:1900126 negative regulation of hyaluronan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900126 down-regulation of hyaluronan synthesis|negative regulation of hyaluronan synthesis|down regulation of hyaluronan biosynthetic process|down regulation of hyaluronan biosynthesis|negative regulation of hyaluronan formation|down-regulation of hyaluronan formation|downregulation of hyaluronan biosynthesis|downregulation of hyaluronan biosynthetic process|downregulation of hyaluronan anabolism|downregulation of hyaluronan synthesis|down regulation of hyaluronan anabolism|downregulation of hyaluronan formation|down regulation of hyaluronan synthesis|down-regulation of hyaluronan biosynthetic process|down-regulation of hyaluronan biosynthesis|negative regulation of hyaluronan biosynthesis|inhibition of hyaluronan anabolism|down regulation of hyaluronan formation|inhibition of hyaluronan synthesis|inhibition of hyaluronan biosynthetic process|inhibition of hyaluronan formation|inhibition of hyaluronan biosynthesis|negative regulation of hyaluronan anabolism|down-regulation of hyaluronan anabolism Any process that stops, prevents or reduces the frequency, rate or extent of hyaluronan biosynthetic process. GO:1900121 negative regulation of receptor binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900121 downregulation of receptor binding|down regulation of receptor binding|inhibition of receptor binding|inhibition of receptor ligand|down regulation of receptor-associated protein activity|down-regulation of receptor binding Any process that stops, prevents or reduces the frequency, rate or extent of a protein or other molecule binding to a receptor. GO:1900120 regulation of receptor binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900120 regulation of receptor ligand Any process that modulates the frequency, rate or extent of a protein or other molecule binding to a receptor. GO:0046299 obsolete 2,4-dichlorophenoxyacetic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046299 2,4-dichlorophenoxyacetic acid anabolism|2,4-dichlorophenoxyacetic acid synthesis|2,4-dichlorophenoxyacetic acid formation|2,4-dichlorophenoxyacetic acid biosynthetic process|2,4-dichlorophenoxyacetic acid biosynthesis OBSOLETE. The chemical reactions and pathways resulting in the formation of 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds. GO:1900123 regulation of nodal receptor complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900123 regulation of nodal receptor complex formation|regulation of ActRIIB.ALK4.EGF-CFC complex formation Any process that modulates the frequency, rate or extent of nodal receptor complex assembly. GO:0046298 2,4-dichlorobenzoate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046298 2,4-dichlorobenzoate degradation|2,4-dichlorobenzoate breakdown|2,4-dichlorobenzoate catabolism The chemical reactions and pathways resulting in the breakdown of 2,4-dichlorobenzoate, a chlorinated aromatic compound which is a key intermediate in the aerobic degradation of polychlorinated biphenyls (PCBs). GO:1900122 positive regulation of receptor binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900122 upregulation of receptor binding|activation of receptor binding|up regulation of receptor binding Any process that activates or increases the frequency, rate or extent of a protein or other molecule binding to a receptor. GO:1900130 regulation of lipid binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900130 Any process that modulates the frequency, rate or extent of lipid binding. GO:0071239 cellular response to streptomycin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071239 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a streptomycin stimulus. Streptomycin is a commonly used antibiotic in cell culture media which acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome. CHEBI:25905 peptide hormone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25905 GO:0071238 cellular response to brefeldin A biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071238 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brefeldin A stimulus. CHEBI:25903 peptide antibiotic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25903 GO:0071237 cellular response to bacteriocin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071237 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacteriocin stimulus. A bacteriocin is a protein substance released by certain bacteria that kills but does not lyse closely related strains of bacteria. Specific bacteriocins attach to specific receptors on cell walls and induce specific metabolic block, e.g. cessation of nucleic acid or protein synthesis of oxidative phosphorylation. GO:0071236 cellular response to antibiotic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071236 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms. GO:0071235 cellular response to proline biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071235 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a proline stimulus. CHEBI:25909 peptidyl-1-thioglycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25909 GO:0071234 cellular response to phenylalanine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071234 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylalanine stimulus. GO:0071233 cellular response to leucine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071233 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leucine stimulus. CHEBI:25907 peptidyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25907 GO:0071232 cellular response to histidine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071232 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histidine stimulus. GO:0071264 positive regulation of translational initiation in response to starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071264 up regulation of translation initiation in response to starvation|positive regulation of translational initiation in response to nutrient starvation|upregulation of translation initiation in response to starvation|stimulation of translation initiation in response to starvation|up-regulation of translation initiation in response to starvation|activation of translation initiation in response to starvation Any process that activates or increases the frequency, rate or extent of translation initiation, as a result of deprivation of nourishment. GO:0071263 negative regulation of translational initiation in response to starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071263 downregulation of translation initiation in response to starvation|down regulation of translation initiation in response to starvation|inhibition of translation initiation in response to starvation|negative regulation of translational initiation in response to nutrient starvation|down-regulation of translation initiation in response to starvation Any process that stops, prevents or reduces the rate of translation initiation, as a result of deprivation of nourishment. GO:0071262 regulation of translational initiation in response to starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071262 regulation of translational initiation in response to nutrient starvation Any process that modulates the frequency, rate or extent of translation initiation, as a result of deprivation of nourishment. GO:0071261 Ssh1 translocon complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071261 Ssh1p-Sss1p-Sbh2p complex A translocon complex that contains a core heterotrimer of alpha, beta and gamma subunits, and may contain additional proteins (translocon-associated proteins or TRAPs); in budding yeast the core proteins are Ssh1p, Sbh2p, and Sss1p. The Ssh1 translocon complex is involved in the cotranslational pathway of protein transport across the ER membrane, and recognizes proteins bearing strongly hydrophobic signal sequences. GO:0071260 cellular response to mechanical stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071260 cellular mechanical stimulus response Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus. GO:1900139 negative regulation of arachidonic acid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900139 downregulation of arachidonic acid secretion|down regulation of arachidonic acid secretion|inhibition of arachidonic acid secretion|down-regulation of arachidonic acid secretion Any process that stops, prevents or reduces the frequency, rate or extent of arachidonic acid secretion. GO:1900136 regulation of chemokine activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900136 Any process that modulates the frequency, rate or extent of chemokine activity. GO:1900135 positive regulation of renin secretion into blood stream biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900135 up-regulation of renin release into blood stream|up regulation of renin secretion into blood stream|activation of renin secretion into blood stream|upregulation of renin release into blood stream|up-regulation of renin secretion into blood stream|up regulation of renin release into blood stream|activation of renin release into blood stream|positive regulation of renin release into blood stream|upregulation of renin secretion into blood stream Any process that activates or increases the frequency, rate or extent of renin secretion into blood stream. GO:1900138 negative regulation of phospholipase A2 activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900138 down regulation of phospholipase A2 activity|downregulation of lecithinase A activity|down regulation of phospholipase A|down regulation of cytosolic phospholipase A2 activity|downregulation of phospholipase A2 activity|down regulation of lecithinase A activity|inhibition of phosphatidase activity|downregulation of phospholipase A|downregulation of secreted phospholipase A2 activity|inhibition of lecithinase A activity|downregulation of cytosolic phospholipase A2 activity|negative regulation of phosphatidolipase activity|down-regulation of phosphatidolipase activity|down regulation of secreted phospholipase A2 activity|negative regulation of phosphatidylcholine 2-acylhydrolase activity|down-regulation of phosphatidylcholine 2-acylhydrolase activity|down-regulation of phospholipase A2 activity|negative regulation of cytosolic phospholipase A2 activity|down-regulation of phospholipase A|down-regulation of cytosolic phospholipase A2 activity|negative regulation of phospholipase A|down-regulation of phosphatidase activity|negative regulation of phosphatidase activity|inhibition of secreted phospholipase A2 activity|downregulation of phosphatidolipase activity|inhibition of phospholipase A2 activity|downregulation of phosphatidylcholine 2-acylhydrolase activity|down regulation of phosphatidolipase activity|down-regulation of lecithinase A activity|inhibition of phosphatidolipase activity|negative regulation of lecithinase A activity|down regulation of phosphatidylcholine 2-acylhydrolase activity|downregulation of phosphatidase activity|inhibition of phosphatidylcholine 2-acylhydrolase activity|inhibition of phospholipase A|inhibition of cytosolic phospholipase A2 activity|negative regulation of secreted phospholipase A2 activity|down-regulation of secreted phospholipase A2 activity|down regulation of phosphatidase activity Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase A2 activity. GO:1900137 negative regulation of chemokine activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900137 down regulation of chemokine activity|inhibition of chemokine activity|down-regulation of chemokine activity|downregulation of chemokine activity Any process that stops, prevents or reduces the frequency, rate or extent of chemokine activity. GO:1900132 positive regulation of lipid binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900132 upregulation of lipid binding|up regulation of lipid binding|activation of lipid binding|up-regulation of lipid binding Any process that activates or increases the frequency, rate or extent of lipid binding. GO:1900131 negative regulation of lipid binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900131 down regulation of lipid binding|downregulation of lipid binding|down-regulation of lipid binding|inhibition of lipid binding Any process that stops, prevents or reduces the frequency, rate or extent of lipid binding. GO:1900134 negative regulation of renin secretion into blood stream biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900134 down-regulation of renin secretion into blood stream|down regulation of renin release into blood stream|inhibition of renin secretion into blood stream|downregulation of renin release into blood stream|down-regulation of renin release into blood stream|negative regulation of renin release into blood stream|down regulation of renin secretion into blood stream|downregulation of renin secretion into blood stream|inhibition of renin release into blood stream Any process that stops, prevents or reduces the frequency, rate or extent of renin secretion into blood stream. GO:1900133 regulation of renin secretion into blood stream biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900133 regulation of renin release into blood stream Any process that modulates the frequency, rate or extent of renin secretion into blood stream. GO:1900141 regulation of oligodendrocyte apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900141 regulation of oligodendrocyte apoptosis Any process that modulates the frequency, rate or extent of oligodendrocyte apoptotic process. GO:1900140 regulation of seedling development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900140 Any process that modulates the frequency, rate or extent of seedling development. GO:0071269 L-homocysteine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071269 L-homocysteine anabolism|L-homocysteine biosynthesis|L-homocysteine synthesis|L-homocysteine formation The chemical reactions and pathways resulting in the formation of L-homocysteine, the L-enantiomer of 2-amino-4-sulfanylbutanoic acid. GO:0071268 homocysteine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071268 homocysteine anabolism|homocysteine biosynthesis|homocysteine synthesis|homocysteine formation The chemical reactions and pathways resulting in the formation of homocysteine, 2-amino-4-sulfanylbutanoic acid. GO:0071267 L-methionine salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071267 Any process that generates L-methionine from derivatives of it, without de novo synthesis. GO:0071266 'de novo' L-methionine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071266 'de novo' L-methionine anabolism|'de novo' L-methionine synthesis|'de novo' L-methionine formation|'de novo' L-methionine biosynthesis The chemical reactions and pathways resulting in the formation of L-methionine, the L-enantiomer of (2S)-2-amino-4-(methylsulfanyl)butanoic acid, from simpler components. GO:0071265 L-methionine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071265 L-methionine formation|L-methionine biosynthesis|L-methionine anabolism|L-methionine synthesis The chemical reactions and pathways resulting in the formation of L-methionine, the L-enantiomer of (2S)-2-amino-4-(methylsulfanyl)butanoic acid. GO:0071253 connexin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071253 Interacting selectively and non-covalently with a connexin, any of a group of related proteins that assemble to form gap junctions. GO:0071252 cellular response to sulfur dioxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071252 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sulfur dioxide (SO2) stimulus. GO:0071251 cellular response to silicon dioxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071251 cellular response to silox|cellular response to silica Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silicon dioxide stimulus. GO:0071250 cellular response to nitrite biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071250 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrite stimulus. GO:1900147 regulation of Schwann cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900147 Any process that modulates the frequency, rate or extent of Schwann cell migration. GO:1900146 negative regulation of nodal signaling pathway involved in determination of left/right asymmetry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900146 down-regulation of nodal signaling pathway involved in determination of left/right asymmetry|inhibition of nodal signaling pathway involved in determination of left/right asymmetry|negative regulation of nodal signalling pathway involved in determination of left/right asymmetry|down regulation of nodal signaling pathway involved in determination of left/right asymmetry|downregulation of nodal signaling pathway involved in determination of left/right asymmetry Any process that stops, prevents or reduces the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry. GO:1900149 positive regulation of Schwann cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900149 up-regulation of Schwann cell migration|activation of Schwann cell migration|up regulation of Schwann cell migration|upregulation of Schwann cell migration Any process that activates or increases the frequency, rate or extent of Schwann cell migration. GO:1900148 negative regulation of Schwann cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900148 down-regulation of Schwann cell migration|downregulation of Schwann cell migration|down regulation of Schwann cell migration|inhibition of Schwann cell migration Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell migration. GO:1900143 positive regulation of oligodendrocyte apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900143 upregulation of oligodendrocyte apoptotic process|up regulation of oligodendrocyte apoptosis|positive regulation of oligodendrocyte apoptosis|up regulation of oligodendrocyte apoptotic process|activation of oligodendrocyte apoptosis|activation of oligodendrocyte apoptotic process|up-regulation of oligodendrocyte apoptosis|up-regulation of oligodendrocyte apoptotic process|upregulation of oligodendrocyte apoptosis Any process that activates or increases the frequency, rate or extent of oligodendrocyte apoptotic process. GO:1900142 negative regulation of oligodendrocyte apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900142 downregulation of oligodendrocyte apoptosis|down regulation of oligodendrocyte apoptotic process|downregulation of oligodendrocyte apoptotic process|negative regulation of oligodendrocyte apoptosis|down-regulation of oligodendrocyte apoptosis|down-regulation of oligodendrocyte apoptotic process|inhibition of oligodendrocyte apoptosis|inhibition of oligodendrocyte apoptotic process|down regulation of oligodendrocyte apoptosis Any process that stops, prevents or reduces the frequency, rate or extent of oligodendrocyte apoptotic process. GO:1900145 regulation of nodal signaling pathway involved in determination of left/right asymmetry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900145 regulation of nodal signalling pathway involved in determination of left/right asymmetry Any process that modulates the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry. GO:1900144 positive regulation of BMP secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900144 activation of bone morphogenetic protein secretion|upregulation of BMP protein secretion|upregulation of BMP secretion|positive regulation of bone morphogenetic protein secretion|up regulation of bone morphogenetic protein secretion|up regulation of BMP protein secretion|positive regulation of BMP protein secretion|activation of BMP protein secretion|up regulation of BMP secretion|activation of BMP secretion|upregulation of bone morphogenetic protein secretion|up-regulation of BMP protein secretion|up-regulation of BMP secretion|up-regulation of bone morphogenetic protein secretion Any process that activates or increases the frequency, rate or extent of BMP secretion. GO:1900150 regulation of defense response to fungus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900150 regulation of response to pathogenic fungus (incompatible interaction)|regulation of defense response to fungi, incompatible interaction|regulation of defence response to fungi|regulation of defense response to fungus, incompatible interaction|regulation of resistance response to pathogenic fungi|regulation of defence response to fungus|regulation of defense response to fungi|regulation of resistance response to pathogenic fungus Any process that modulates the frequency, rate or extent of defense response to fungus. GO:1900152 negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900152 down-regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|down-regulation of mRNA catabolic process, deadenylation-dependent|down-regulation of nuclear mRNA catabolic process, deadenylation-dependent decay|negative regulation of nuclear mRNA catabolic process, deadenylation-dependent decay|downregulation of deadenylation-dependent mRNA decay|negative regulation of mRNA catabolic process, deadenylation-dependent|downregulation of mRNA breakdown, deadenylation-dependent decay|downregulation of mRNA catabolism, deadenylylation-dependent|down regulation of mRNA degradation, deadenylation-dependent decay|down regulation of deadenylation-dependent mRNA decay|inhibition of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|down-regulation of mRNA catabolism, deadenylation-dependent|negative regulation of mRNA catabolism, deadenylation-dependent|down regulation of mRNA catabolism, deadenylylation-dependent|downregulation of mRNA degradation, deadenylation-dependent decay|down regulation of mRNA catabolic process, deadenylylation-dependent|inhibition of deadenylation-dependent mRNA decay|inhibition of mRNA catabolic process, deadenylation-dependent|inhibition of nuclear mRNA catabolic process, deadenylation-dependent decay|inhibition of mRNA catabolism, deadenylylation-dependent|downregulation of mRNA catabolic process, deadenylylation-dependent|down-regulation of mRNA breakdown, deadenylation-dependent decay|negative regulation of mRNA breakdown, deadenylation-dependent decay|down-regulation of mRNA degradation, deadenylation-dependent decay|negative regulation of mRNA degradation, deadenylation-dependent decay|downregulation of mRNA catabolism, deadenylation-dependent|inhibition of mRNA breakdown, deadenylation-dependent decay|down regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|down regulation of nuclear mRNA catabolic process, deadenylation-dependent decay|down regulation of mRNA catabolic process, deadenylation-dependent|down regulation of mRNA catabolism, deadenylation-dependent|negative regulation of mRNA catabolic process, deadenylylation-dependent|down-regulation of mRNA catabolic process, deadenylylation-dependent|downregulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|inhibition of mRNA catabolism, deadenylation-dependent|inhibition of mRNA degradation, deadenylation-dependent decay|down-regulation of deadenylation-dependent mRNA decay|negative regulation of deadenylation-dependent mRNA decay|downregulation of nuclear mRNA catabolic process, deadenylation-dependent decay|downregulation of mRNA catabolic process, deadenylation-dependent|down-regulation of mRNA catabolism, deadenylylation-dependent|negative regulation of mRNA catabolism, deadenylylation-dependent|inhibition of mRNA catabolic process, deadenylylation-dependent|down regulation of mRNA breakdown, deadenylation-dependent decay Any process that stops, prevents or reduces the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay. GO:1900151 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900151 regulation of mRNA breakdown, deadenylation-dependent decay|regulation of deadenylation-dependent mRNA decay|regulation of mRNA catabolism, deadenylylation-dependent|regulation of mRNA degradation, deadenylation-dependent decay|regulation of mRNA catabolic process, deadenylylation-dependent|regulation of mRNA catabolism, deadenylation-dependent|regulation of mRNA catabolic process, deadenylation-dependent|regulation of nuclear mRNA catabolic process, deadenylation-dependent decay Any process that modulates the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay. GO:0071259 cellular response to magnetism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071259 cellular response to magnetic stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnetic stimulus. GO:0071258 cellular response to gravity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071258 cellular response to gravitational stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus. GO:0071257 cellular response to electrical stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071257 cellular response to electricity Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. GO:0071256 translocon complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0071256 Sec complex-associated translocon complex A protein complex that constitutes a specific site of protein translocation across the endoplasmic reticulum, which involves the signal recognition particle receptor. The complex contains a core heterotrimer of alpha, beta and gamma subunits, and may contain additional proteins. GO:0071255 Cvt vesicle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071255 Cvt vesicle formation|cytoplasm to vacuole targeting vesicle assembly|cytoplasm-to-vacuole targetin vesicle assembly|Cvt vesicle biosynthesis A vesicle organization process that takes place as part of the Cvt pathway, and results in the formation of a double membrane-bounded cytosolic structure that sequesters precursor aminopeptidase I (prAPI). GO:0071254 cytoplasmic U snRNP body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071254 U-body|U body A ribonucleoprotein complex that can be visualized as a focus in the cytoplasm, and contains uridine-rich small nuclear ribonucleoproteins (U snRNPs) and essential snRNP assembly factors. These U bodies are invariably found in association with P bodies. GO:0071286 cellular response to magnesium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071286 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus. GO:0071285 cellular response to lithium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071285 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lithium (Li+) ion stimulus. GO:0071284 cellular response to lead ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071284 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus. GO:0071283 cellular response to iron(III) ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071283 cellular response to iron(III) Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(III) ion stimulus. GO:0071282 cellular response to iron(II) ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071282 cellular response to iron(II) Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(II) ion stimulus. GO:0071281 cellular response to iron ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071281 cellular response to iron Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus. GO:0071280 cellular response to copper ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071280 cellular response to copper Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus. GO:1900158 negative regulation of bone mineralization involved in bone maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900158 inhibition of bone mineralization involved in bone maturation|down regulation of bone mineralization involved in bone maturation|downregulation of bone mineralization involved in bone maturation|down-regulation of bone mineralization involved in bone maturation Any process that stops, prevents or reduces the frequency, rate or extent of bone mineralization involved in bone maturation. GO:1900157 regulation of bone mineralization involved in bone maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900157 Any process that modulates the frequency, rate or extent of bone mineralization involved in bone maturation. GO:1900159 positive regulation of bone mineralization involved in bone maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900159 up-regulation of bone mineralization involved in bone maturation|upregulation of bone mineralization involved in bone maturation|up regulation of bone mineralization involved in bone maturation|activation of bone mineralization involved in bone maturation Any process that activates or increases the frequency, rate or extent of bone mineralization involved in bone maturation. GO:1900154 regulation of bone trabecula formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900154 regulation of skeletal trabecula biogenesis|regulation of bone trabeculation|regulation of bone trabecula biogenesis|regulation of skeletal trabeculation|regulation of skeletal trabecula formation Any process that modulates the frequency, rate or extent of bone trabecula formation. GO:1900153 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900153 up regulation of deadenylation-dependent mRNA decay|positive regulation of mRNA catabolism, deadenylylation-dependent|upregulation of mRNA degradation, deadenylation-dependent decay|up regulation of mRNA catabolism, deadenylylation-dependent|up-regulation of mRNA catabolism, deadenylation-dependent|activation of mRNA catabolism, deadenylation-dependent|upregulation of mRNA catabolic process, deadenylylation-dependent|up regulation of mRNA breakdown, deadenylation-dependent decay|up-regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|positive regulation of mRNA breakdown, deadenylation-dependent decay|activation of mRNA breakdown, deadenylation-dependent decay|up-regulation of nuclear mRNA catabolic process, deadenylation-dependent decay|upregulation of deadenylation-dependent mRNA decay|up-regulation of mRNA catabolic process, deadenylation-dependent|upregulation of mRNA catabolism, deadenylylation-dependent|up regulation of mRNA degradation, deadenylation-dependent decay|positive regulation of mRNA catabolism, deadenylation-dependent|positive regulation of mRNA degradation, deadenylation-dependent decay|activation of mRNA degradation, deadenylation-dependent decay|up regulation of mRNA catabolism, deadenylation-dependent|up regulation of mRNA catabolic process, deadenylylation-dependent|upregulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|activation of mRNA catabolic process, deadenylylation-dependent|positive regulation of mRNA catabolic process, deadenylylation-dependent|upregulation of mRNA catabolic process, deadenylation-dependent|upregulation of nuclear mRNA catabolic process, deadenylation-dependent decay|up-regulation of deadenylation-dependent mRNA decay|activation of deadenylation-dependent mRNA decay|up-regulation of mRNA breakdown, deadenylation-dependent decay|up-regulation of mRNA catabolism, deadenylylation-dependent|activation of mRNA catabolism, deadenylylation-dependent|upregulation of mRNA catabolism, deadenylation-dependent|up-regulation of mRNA degradation, deadenylation-dependent decay|up regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|up regulation of mRNA catabolic process, deadenylation-dependent|activation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|up regulation of nuclear mRNA catabolic process, deadenylation-dependent decay|up-regulation of mRNA catabolic process, deadenylylation-dependent|upregulation of mRNA breakdown, deadenylation-dependent decay|positive regulation of deadenylation-dependent mRNA decay|positive regulation of nuclear mRNA catabolic process, deadenylation-dependent decay|activation of mRNA catabolic process, deadenylation-dependent|positive regulation of mRNA catabolic process, deadenylation-dependent|activation of nuclear mRNA catabolic process, deadenylation-dependent decay Any process that activates or increases the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay. GO:1900156 positive regulation of bone trabecula formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900156 up-regulation of skeletal trabeculation|positive regulation of bone trabeculation|activation of skeletal trabeculation|up regulation of bone trabeculation|up regulation of skeletal trabecula biogenesis|upregulation of bone trabecula biogenesis|up-regulation of skeletal trabecula formation|positive regulation of skeletal trabecula biogenesis|activation of skeletal trabecula formation|up regulation of bone trabecula formation|activation of skeletal trabecula biogenesis|positive regulation of skeletal trabeculation|upregulation of bone trabeculation|up regulation of skeletal trabeculation|up regulation of bone trabecula biogenesis|positive regulation of skeletal trabecula formation|up-regulation of skeletal trabecula biogenesis|upregulation of bone trabecula formation|positive regulation of bone trabecula biogenesis|up regulation of skeletal trabecula formation|activation of bone trabecula biogenesis|up-regulation of bone trabeculation|activation of bone trabeculation|upregulation of skeletal trabeculation|up-regulation of bone trabecula formation|upregulation of skeletal trabecula biogenesis|activation of bone trabecula formation|upregulation of skeletal trabecula formation|up-regulation of bone trabecula biogenesis Any process that activates or increases the frequency, rate or extent of bone trabecula formation. GO:1900155 negative regulation of bone trabecula formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900155 down regulation of skeletal trabecula biogenesis|negative regulation of bone trabeculation|down-regulation of bone trabeculation|down-regulation of bone trabecula formation|inhibition of bone trabecula biogenesis|downregulation of skeletal trabecula biogenesis|downregulation of bone trabeculation|down regulation of bone trabecula biogenesis|down-regulation of skeletal trabeculation|negative regulation of skeletal trabeculation|negative regulation of skeletal trabecula biogenesis|downregulation of bone trabecula formation|down-regulation of skeletal trabecula biogenesis|down regulation of bone trabeculation|downregulation of bone trabecula biogenesis|negative regulation of skeletal trabecula formation|inhibition of bone trabeculation|down-regulation of skeletal trabecula formation|down regulation of bone trabecula formation|inhibition of bone trabecula formation|downregulation of skeletal trabeculation|down-regulation of bone trabecula biogenesis|negative regulation of bone trabecula biogenesis|downregulation of skeletal trabecula formation|down regulation of skeletal trabeculation|inhibition of skeletal trabecula biogenesis|inhibition of skeletal trabeculation|down regulation of skeletal trabecula formation|inhibition of skeletal trabecula formation Any process that stops, prevents or reduces the frequency, rate or extent of bone trabecula formation. GO:1900161 regulation of phospholipid scramblase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900161 Any process that modulates the frequency, rate or extent of phospholipid scramblase activity. GO:1900160 plastid DNA packaging biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900160 DNA organization in plastid|DNA organisation in plastid|plastidial DNA packaging Any process in which plastidial DNA and associated proteins are formed into a compact, orderly structure. GO:1900163 positive regulation of phospholipid scramblase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900163 up-regulation of phospholipid scramblase activity|activation of phospholipid scramblase activity|up regulation of phospholipid scramblase activity|upregulation of phospholipid scramblase activity Any process that activates or increases the frequency, rate or extent of phospholipid scramblase activity. GO:1900162 negative regulation of phospholipid scramblase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900162 down-regulation of phospholipid scramblase activity|downregulation of phospholipid scramblase activity|down regulation of phospholipid scramblase activity|inhibition of phospholipid scramblase activity Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid scramblase activity. GO:0071289 cellular response to nickel ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071289 cellular response to nickel Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nickel ion stimulus. GO:0071288 cellular response to mercury ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071288 cellular response to mercuric ion|cellular response to mercury Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercury ion stimulus. GO:0071287 cellular response to manganese ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071287 cellular response to manganese Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus. GO:0071275 cellular response to aluminum ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071275 cellular response to aluminium ion|cellular response to aluminum Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aluminum ion stimulus. GO:0071274 isoquinoline alkaloid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071274 isoquinoline alkaloid catabolism|ipecac alkaloid catabolism|isoquinoline alkaloid degradation|isoquinoline alkaloid breakdown The chemical reactions and pathways resulting in the breakdown of isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin. GO:0071273 morphine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071273 UniPathway:Q02198 morphine degradation|morphine breakdown|morphine catabolism The chemical reactions and pathways resulting in the breakdown of morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum. OBO:GOCHE_38157 substance with iron chelator role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_38157 GO:0071272 morphine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071272 Wikipedia:Morphine morphine metabolism The chemical reactions and pathways involving morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum. GO:0071271 1-butanol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071271 1-butanol synthesis|1-butanol formation|1-butanol biosynthesis|butanol biosynthetic process|butan-1-ol biosynthetic process|1-butanol anabolism The chemical reactions and pathways resulting in the formation of 1-butanol, an alkyl primary alcohol with the formula C4H10O. GO:0071270 1-butanol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071270 butanol metabolic process|1-butanol metabolism|butan-1-ol metabolic process The chemical reactions and pathways involving 1-butanol, an alkyl primary alcohol with the formula C4H10O. UBERON:0036186 fibroelastic connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036186 GO:1900169 regulation of glucocorticoid mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900169 regulation of glucocorticoid mediated signalling Any process that modulates the frequency, rate or extent of glucocorticoid mediated signaling pathway. GO:1900168 positive regulation of glial cell-derived neurotrophic factor production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900168 positive regulation of glial cell-derived neurotrophic factor secretion|positive regulation of GDNF production|positive regulation of glial cell line-derived neurotrophic factor secretion|activation of glial cell line-derived neurotrophic factor secretion Any process that activates or increases the frequency, rate or extent of glial cell-derived neurotrophic factor production. GO:1900165 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1900165 GO:1900164 nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900164 nodal signalling pathway involved in determination of lateral mesoderm left/right asymmetry|nodal signaling of determination of left/right asymmetry in lateral mesoderm|nodal signaling pathway of determination of left/right asymmetry in lateral mesoderm A series of molecular signals initiated by the binding of a nodal protein to an activin receptor on the surface of a target cell, which contributes to the establishment of lateral mesoderm with respect to the left and right halves. GO:1900167 negative regulation of glial cell-derived neurotrophic factor production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900167 inhibition of glial cell line-derived neurotrophic factor secretion|negative regulation of GDNF secretion|inhibition of GDNF secretion|negative regulation of glial cell line-derived neurotrophic factor secretion|negative regulation of glial cell-derived neurotrophic factor secretion Any process that stops, prevents or reduces the frequency, rate or extent of glial cell-derived neurotrophic factor production. GO:1900166 regulation of glial cell-derived neurotrophic factor production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900166 regulation of glial cell-derived neurotrophic factor secretion|regulation of glial cell line-derived neurotrophic factor secretion|regulation of GDNF secretion Any process that modulates the frequency, rate or extent of glial cell-derived neurotrophic factor production. GO:1900172 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1900172 GO:1900171 positive regulation of glucocorticoid mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900171 up-regulation of glucocorticoid mediated signalling|activation of glucocorticoid mediated signalling|up regulation of glucocorticoid mediated signaling pathway|activation of glucocorticoid mediated signaling pathway|positive regulation of glucocorticoid mediated signalling|up regulation of glucocorticoid mediated signalling|up-regulation of glucocorticoid mediated signaling pathway|upregulation of glucocorticoid mediated signalling|upregulation of glucocorticoid mediated signaling pathway Any process that activates or increases the frequency, rate or extent of glucocorticoid mediated signaling pathway. GO:1900174 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1900174 GO:1900173 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1900173 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900170 down regulation of glucocorticoid mediated signaling pathway|downregulation of glucocorticoid mediated signaling pathway|negative regulation of glucocorticoid mediated signalling|down-regulation of glucocorticoid mediated signalling|down-regulation of glucocorticoid mediated signaling pathway|downregulation of glucocorticoid mediated signalling|inhibition of glucocorticoid mediated signaling pathway|down regulation of glucocorticoid mediated signalling|inhibition of glucocorticoid mediated signalling Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid mediated signaling pathway. GO:0071279 cellular response to cobalt ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071279 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt ion stimulus. GO:0071278 cellular response to cesium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071278 cellular response to cesium Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cesium stimulus. GO:0071277 cellular response to calcium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071277 cellular response to Ca2+ ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus. GO:0071276 cellular response to cadmium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071276 cellular response to cadmium Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus. OBO:GOCHE_38161 substance with chelator role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_38161 GO:1900179 positive regulation of aflatoxin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900179 positive regulation of aflatoxin synthesis|up regulation of aflatoxin formation|activation of aflatoxin formation|positive regulation of aflatoxin formation|positive regulation of aflatoxin biosynthesis|up regulation of aflatoxin biosynthesis|up regulation of aflatoxin biosynthetic process|up-regulation of aflatoxin anabolism|up-regulation of aflatoxin synthesis|up-regulation of aflatoxin formation|upregulation of aflatoxin anabolism|upregulation of aflatoxin biosynthesis|upregulation of aflatoxin biosynthetic process|upregulation of aflatoxin synthesis|upregulation of aflatoxin formation|activation of aflatoxin biosynthesis|up-regulation of aflatoxin biosynthetic process|up-regulation of aflatoxin biosynthesis|activation of aflatoxin biosynthetic process|up regulation of aflatoxin anabolism|activation of aflatoxin anabolism|positive regulation of aflatoxin anabolism|up regulation of aflatoxin synthesis|activation of aflatoxin synthesis Any process that activates or increases the frequency, rate or extent of aflatoxin biosynthetic process. GO:1900176 negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900176 down-regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry|downregulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry|inhibition of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry|negative regulation of nodal signalling pathway involved in determination of lateral mesoderm left/right asymmetry Any process that stops, prevents or reduces the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry in the lateral mesoderm. GO:1900175 regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900175 regulation of nodal signalling pathway involved in determination of lateral mesoderm left/right asymmetry Any process that modulates the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry in the lateral mesoderm. GO:1900178 negative regulation of aflatoxin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900178 down-regulation of aflatoxin synthesis|negative regulation of aflatoxin synthesis|down-regulation of aflatoxin formation|inhibition of aflatoxin anabolism|negative regulation of aflatoxin formation|downregulation of aflatoxin biosynthesis|downregulation of aflatoxin biosynthetic process|inhibition of aflatoxin synthesis|down regulation of aflatoxin biosynthetic process|down regulation of aflatoxin biosynthesis|inhibition of aflatoxin formation|inhibition of aflatoxin biosynthetic process|inhibition of aflatoxin biosynthesis|down regulation of aflatoxin anabolism|downregulation of aflatoxin anabolism|down regulation of aflatoxin synthesis|down regulation of aflatoxin formation|downregulation of aflatoxin synthesis|downregulation of aflatoxin formation|negative regulation of aflatoxin biosynthesis|down-regulation of aflatoxin anabolism|negative regulation of aflatoxin anabolism|down-regulation of aflatoxin biosynthetic process|down-regulation of aflatoxin biosynthesis Any process that stops, prevents or reduces the frequency, rate or extent of aflatoxin biosynthetic process. GO:1900177 regulation of aflatoxin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900177 regulation of aflatoxin biosynthesis|regulation of aflatoxin anabolism|regulation of aflatoxin synthesis|regulation of aflatoxin formation Any process that modulates the frequency, rate or extent of aflatoxin biosynthetic process. GO:1900183 regulation of xanthone-containing compound biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900183 regulation of xanthone-containing compound anabolism|regulation of xanthone-containing compound synthesis|regulation of xanthone-containing compound formation|regulation of xanthone-containing compound biosynthesis|regulation of xanthone biosynthesis|regulation of xanthone biosynthetic process Any process that modulates the frequency, rate or extent of xanthone-containing compound biosynthetic process. GO:1900182 positive regulation of protein localization to nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900182 up-regulation of protein localisation to nucleus|up-regulation of protein localization in cell nucleus|activation of protein localization in cell nucleus|up regulation of protein localization in nucleus|upregulation of protein localization to nucleus|positive regulation of protein localization in nucleus|activation of protein localization in nucleus|upregulation of protein localisation to nucleus|up regulation of protein localization to nucleus|positive regulation of protein localization in cell nucleus|activation of protein localization to nucleus|up regulation of protein localization in cell nucleus|up-regulation of protein localization in nucleus|up regulation of protein localisation to nucleus|activation of protein localisation to nucleus|positive regulation of protein localisation to nucleus|upregulation of protein localization in cell nucleus|upregulation of protein localization in nucleus|up-regulation of protein localization to nucleus Any process that activates or increases the frequency, rate or extent of protein localization to nucleus. GO:1900185 positive regulation of xanthone-containing compound biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900185 up regulation of xanthone-containing compound anabolism|activation of xanthone-containing compound formation|up regulation of xanthone biosynthesis|up regulation of xanthone biosynthetic process|positive regulation of xanthone-containing compound synthesis|positive regulation of xanthone biosynthesis|up-regulation of xanthone-containing compound biosynthetic process|positive regulation of xanthone biosynthetic process|up-regulation of xanthone-containing compound biosynthesis|up regulation of xanthone-containing compound synthesis|positive regulation of xanthone-containing compound formation|up regulation of xanthone-containing compound formation|activation of xanthone biosynthetic process|activation of xanthone biosynthesis|upregulation of xanthone-containing compound anabolism|upregulation of xanthone-containing compound biosynthetic process|upregulation of xanthone-containing compound biosynthesis|up-regulation of xanthone biosynthesis|up-regulation of xanthone biosynthetic process|upregulation of xanthone-containing compound synthesis|upregulation of xanthone-containing compound formation|up-regulation of xanthone-containing compound anabolism|up regulation of xanthone-containing compound biosynthesis|up regulation of xanthone-containing compound biosynthetic process|upregulation of xanthone biosynthetic process|upregulation of xanthone biosynthesis|up-regulation of xanthone-containing compound synthesis|activation of xanthone-containing compound biosynthetic process|positive regulation of xanthone-containing compound biosynthesis|activation of xanthone-containing compound anabolism|up-regulation of xanthone-containing compound formation|activation of xanthone-containing compound biosynthesis|activation of xanthone-containing compound synthesis|positive regulation of xanthone-containing compound anabolism Any process that activates or increases the frequency, rate or extent of xanthone-containing compound biosynthetic process. GO:1900184 negative regulation of xanthone-containing compound biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900184 down-regulation of xanthone-containing compound formation|negative regulation of xanthone-containing compound formation|inhibition of xanthone-containing compound biosynthetic process|downregulation of xanthone-containing compound anabolism|negative regulation of xanthone biosynthesis|down-regulation of xanthone biosynthetic process|negative regulation of xanthone biosynthetic process|down-regulation of xanthone biosynthesis|downregulation of xanthone-containing compound synthesis|down regulation of xanthone-containing compound anabolism|inhibition of xanthone-containing compound biosynthesis|downregulation of xanthone-containing compound formation|down regulation of xanthone-containing compound synthesis|negative regulation of xanthones anabolism|inhibition of xanthone-containing compound anabolism|down regulation of xanthone-containing compound formation|down regulation of xanthone-containing compound biosynthesis|down regulation of xanthone-containing compound biosynthetic process|inhibition of xanthone biosynthetic process|inhibition of xanthone-containing compound synthesis|inhibition of xanthone biosynthesis|downregulation of xanthone-containing compound biosynthesis|downregulation of xanthone-containing compound biosynthetic process|inhibition of xanthone-containing compound formation|down regulation of xanthone biosynthetic process|down regulation of xanthone biosynthesis|down-regulation of xanthone-containing compound anabolism|negative regulation of xanthone-containing compound anabolism|negative regulation of xanthone-containing compound biosynthesis|down-regulation of xanthone-containing compound biosynthetic process|down-regulation of xanthone-containing compound biosynthesis|downregulation of xanthone biosynthetic process|downregulation of xanthone biosynthesis|down-regulation of xanthone-containing compound synthesis|negative regulation of xanthone-containing compound synthesis Any process that stops, prevents or reduces the frequency, rate or extent of xanthone-containing compound biosynthetic process. GO:1900181 negative regulation of protein localization to nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900181 inhibition of protein localisation to nucleus|down regulation of protein localization to nucleus|negative regulation of protein localization in cell nucleus|negative regulation of protein localization in nucleus|down-regulation of protein localization in nucleus|down-regulation of protein localization in cell nucleus|downregulation of protein localization to nucleus|down regulation of protein localisation to nucleus|inhibition of protein localization in nucleus|downregulation of protein localisation to nucleus|downregulation of protein localization in cell nucleus|down-regulation of protein localization to nucleus|down regulation of protein localization in cell nucleus|inhibition of protein localization in cell nucleus|negative regulation of protein localisation to nucleus|down-regulation of protein localisation to nucleus|inhibition of protein localization to nucleus|down regulation of protein localization in nucleus|downregulation of protein localization in nucleus Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleus. GO:1900180 regulation of protein localization to nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900180 regulation of protein localisation to nucleus|regulation of protein localization in cell nucleus|regulation of protein localization in nucleus Any process that modulates the frequency, rate or extent of protein localization to nucleus. GO:0071297 cellular response to cobalamin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071297 cellular response to vitamin B12 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalamin (vitamin B12) stimulus. GO:0071296 cellular response to biotin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071296 cellular response to vitamin B7|cellular response to vitamin H|cellular response to coenzyme R|cellular response to Bios IIB Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotin stimulus. GO:0071295 cellular response to vitamin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071295 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus. GO:0071294 cellular response to zinc ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071294 cellular response to zinc Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus. GO:0071293 cellular response to tellurium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071293 cellular response to tellurium Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tellurium ion stimulus. GO:0071292 cellular response to silver ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071292 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silver ion stimulus. GO:0071291 cellular response to selenium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071291 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from selenium ion. GO:0071290 cellular response to platinum ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071290 cellular response to platinum Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platinum stimulus. GO:1900187 regulation of cell adhesion involved in single-species biofilm formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900187 regulation of cell adhesion during single-species biofilm formation Any process that modulates the frequency, rate or extent of cell adhesion involved in single-species biofilm formation. GO:1900186 negative regulation of clathrin-dependent endocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900186 inhibition of clathrin coated pit-dependent endocytosis|down-regulation of clathrin-mediated endocytosis|downregulation of clathrin-dependent endocytosis|down regulation of clathrin coated pit-dependent endocytosis|down regulation of clathrin-dependent endocytosis|inhibition of clathrin-mediated endocytosis|downregulation of clathrin coated pit-dependent endocytosis|inhibition of clathrin-dependent endocytosis|negative regulation of clathrin-mediated endocytosis|negative regulation of clathrin coated pit-dependent endocytosis|down-regulation of clathrin coated pit-dependent endocytosis|down regulation of clathrin-mediated endocytosis|downregulation of clathrin-mediated endocytosis|negative regulation of clathrin-dependent endocytosis|down-regulation of clathrin-dependent endocytosis Any process that stops, prevents or reduces the frequency, rate or extent of clathrin-mediated endocytosis. GO:1900189 positive regulation of cell adhesion involved in single-species biofilm formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900189 up regulation of cell adhesion during single-species biofilm formation|up-regulation of cell adhesion involved in single-species biofilm formation|positive regulation of cell adhesion during single-species biofilm formation|activation of cell adhesion involved in single-species biofilm formation|activation of cell adhesion during single-species biofilm formation|up-regulation of cell adhesion during single-species biofilm formation|up regulation of cell adhesion involved in single-species biofilm formation|upregulation of cell adhesion during single-species biofilm formation|upregulation of cell adhesion involved in single-species biofilm formation Any process that activates or increases the frequency, rate or extent of cell adhesion involved in single-species biofilm formation. GO:1900188 negative regulation of cell adhesion involved in single-species biofilm formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900188 downregulation of cell adhesion during single-species biofilm formation|down-regulation of cell adhesion during single-species biofilm formation|negative regulation of cell adhesion during single-species biofilm formation|down-regulation of cell adhesion involved in single-species biofilm formation|downregulation of cell adhesion involved in single-species biofilm formation|inhibition of cell adhesion during single-species biofilm formation|down regulation of cell adhesion involved in single-species biofilm formation|inhibition of cell adhesion involved in single-species biofilm formation|down regulation of cell adhesion during single-species biofilm formation Any process that stops, prevents or reduces the frequency, rate or extent of cell adhesion involved in single-species biofilm formation. GO:1900194 negative regulation of oocyte maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900194 downregulation of oocyte maturation|down-regulation of oocyte maturation|inhibition of oocyte maturation|down regulation of oocyte maturation Any process that stops, prevents or reduces the frequency, rate or extent of oocyte maturation. GO:1900193 regulation of oocyte maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900193 Any process that modulates the frequency, rate or extent of oocyte maturation. GO:1900196 regulation of penicillin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900196 regulation of penicillin anabolism|regulation of penicillin synthesis|regulation of penicillin formation|regulation of penicillin biosynthesis Any process that modulates the frequency, rate or extent of penicillin biosynthetic process. GO:1900195 positive regulation of oocyte maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900195 up regulation of oocyte maturation|activation of oocyte maturation|up-regulation of oocyte maturation|upregulation of oocyte maturation Any process that activates or increases the frequency, rate or extent of oocyte maturation. GO:1900190 regulation of single-species biofilm formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900190 Any process that modulates the frequency, rate or extent of single-species biofilm formation. GO:1900192 positive regulation of single-species biofilm formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900192 up-regulation of single-species biofilm formation|activation of single-species biofilm formation|up regulation of single-species biofilm formation|upregulation of single-species biofilm formation Any process that activates or increases the frequency, rate or extent of single-species biofilm formation. GO:1900191 negative regulation of single-species biofilm formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900191 down-regulation of single-species biofilm formation|downregulation of single-species biofilm formation|down regulation of single-species biofilm formation|inhibition of single-species biofilm formation Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation. GO:0071299 cellular response to vitamin A biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071299 cellular response to retinol Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin A stimulus. GO:0071298 cellular response to L-ascorbic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071298 cellular response to vitamin C|cellular response to ascorbic acid|cellular response to L-ascorbate Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-ascorbic acid (vitamin C) stimulus. CHEBI:25973 phenylacetaldehydes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25973 CHEBI:25978 phenylacetic acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25978 CHEBI:50934 N-acyl-Delta(8)-phytosphingenine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50934 GO:0046206 trypanothione metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046206 trypanothione metabolism The chemical reactions and pathways involving trypanothione (N1,N6,-bis(glutathionyl)spermidine), an essential redox intermediate in intracellular thiol redox regulation which also plays a role in protecting against oxidative stress. GO:0046205 nor-spermidine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046205 nor-spermidine catabolism|nor-spermidine degradation|nor-spermidine breakdown The chemical reactions and pathways resulting in the breakdown of nor-spermidine, a compound related to spermidine, N-(3-aminopropyl)-1,4-diaminobutane. GO:0046204 nor-spermidine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046204 nor-spermidine metabolism The chemical reactions and pathways involving nor-spermidine, a compound related to spermidine, N-(3-aminopropyl)-1,4-diaminobutane. GO:0046203 spermidine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046203 spermidine catabolism|spermidine degradation|spermidine breakdown The chemical reactions and pathways resulting in the breakdown of spermidine, N-(3-aminopropyl)-1,4-diaminobutane. GO:0046202 cyanide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046202 cyanide formation|cyanide biosynthesis|cyanide anabolism|cyanide synthesis The chemical reactions and pathways resulting in the formation of cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration. CHEBI:25970 phenoxazine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25970 GO:0046201 cyanate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046201 cyanate anabolism|cyanate synthesis|cyanate formation|cyanate biosynthesis The chemical reactions and pathways resulting in the formation of cyanate, NCO-, the anion of cyanic acid. GO:0046200 obsolete m-cresol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046200 m-cresol biosynthetic process|m-cresol biosynthesis|m-cresol anabolism|m-cresol synthesis|m-cresol formation OBSOLETE. The chemical reactions and pathways resulting in the formation of m-cresol (3-hydroxytoluene), the meta-isoform of cresol. UBERON:0012168 umbilical cord blood biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012168 fetal blood|cord blood|umbilical cord blood blood that remains in the placenta and in the attached umbilical cord after childbirth[WP]. CHEBI:84266 1,2-ditetradecanoyl-sn-glycerol-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84266 CHEBI:11320 13-hydroxydocosanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_11320 GO:0061841 high-affinity iron exporter complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061841 IntAct:EBI-12592993 high affinity iron exporter complex|FET5-FTH1 high-affinity iron exporter complex|FET5-FTH1 high affinity iron exporter complex A protein complex which transports ferrous iron (Fe(III) or Fe3+) ions from the vacuole, the main storage component of intracellular free iron, into the cytoplasm in a low iron environment. GO:0061840 high-affinity ferrous iron transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061840 high affinity ferrous uptake transmembrane transporter activity|high-affinity ferrous iron uptake transmembrane transporter activity Enables the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. CHEBI:84264 EC 3.5.1.19 (nicotinamidase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84264 GO:0061843 Sertoli cell barrier remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061843 restructuring of SCB|blood testis barrier restructuring|restructuring of blood-testis barrier|restructuring of BTB|Sertoli cell barrier restructuring|SCB remodeling The tissue remodeling process by which the Sertoli cell barrier is temporarily disrupted and reorganized to accommodate the transit of preleptotene spermatocytes at stage VIII of the epithelial cycle. CHEBI:84263 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4-phosphate) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84263 GO:0061842 microtubule organizing center localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061842 microtubule organizing center polarity|MTOC localization|MTOC polarity Any process in which the microtubule organizing center is transported to, and/or maintained in, a specific location within the cell. GO:0046209 nitric oxide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046209 nitric oxide metabolism The chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water. GO:0061845 neuron projection branch point biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061845 The location where a secondary projection arises from a neuron projection. GO:0046208 spermine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046208 spermine catabolism|spermine degradation|spermine breakdown The chemical reactions and pathways resulting in the breakdown of spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses and involved in nucleic acid packaging. GO:0046207 trypanothione catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046207 trypanothione catabolism|trypanothione degradation|trypanothione breakdown The chemical reactions and pathways resulting in the breakdown of trypanothione (N1,N6,-bis(glutathionyl)spermidine), an essential redox intermediate in intracellular thiol redox regulation which also plays a role in protecting against oxidative stress. GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061844 peptide-mediated antimicrobial humoral response|antimicrobial peptide-mediated antimicrobial humoral response An immune response against microbes mediated by anti-microbial peptides in body fluid. GO:0061847 response to cholecystokinin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061847 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholecystokinin stimulus. GO:0061846 dendritic spine cytoplasm biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061846 The region of the neuronal cytoplasm located in dendritic spines. GO:0061849 telomeric G-quadruplex DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061849 Interacting selectively and non-covalently with telomeric G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures in telomeres. CHEBI:25979 phenylacetonitrile biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_25979 GO:0061848 cellular response to cholecystokinin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061848 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholecystokinin stimulus. CHEBI:25985 phenylalanine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25985 CHEBI:50923 5-deoxy-D-glucuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50923 UBERON:0012152 skeleton of pedal digitopodium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012152 pedal digitopodium A subdivision of the pes skeleton consisting of both pedal acropodial skeleton and metatarsal skeleton, but excluding the tarsal skeleton. UBERON:0012151 skeleton of manual digitopodium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012151 manual digitopodium A subdivision of the manus skeleton consisting of both manual acropodial skeleton and metacarpal skeleton, but excluding the carpal skeleton. UBERON:0012150 skeleton of digitopodium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012150 digitopodium|skeleton of digits A subdivision of the autopod skeleton consisting of both acropodial skeleon and metapodial skeleton, but excluding the mesopodial/basopodial skeleton. CHEBI:50920 2D-2,3,5/4,6-pentahydroxycyclohexanone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50920 GO:0046217 indole phytoalexin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046217 indole phytoalexin metabolism The chemical reactions and pathways involving indole phytoalexins, any indole compound produced by plants as part of their defense response. CHEBI:50927 angiogenesis inducing agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50927 GO:0046216 indole phytoalexin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046216 indole phytoalexin breakdown|indole phytoalexin catabolism|indole phytoalexin degradation The chemical reactions and pathways resulting in the breakdown of indole phytoalexins, any indole compound produced by plants as part of their defense response. CHEBI:35307 epoxycarotenol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35307 CHEBI:50926 angiogenesis modulating agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50926 GO:0046215 siderophore catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046215 siderochrome catabolism|siderophore degradation|siderophore catabolism|siderophore breakdown The chemical reactions and pathways resulting in the breakdown of siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action. CHEBI:50925 EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50925 UBERON:0036146 cardiopharyngeal field biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036146 An region of the mesoderm that includes anterior lateral mesoderm of the first heart field plus contiguous pharyngeal mesoderm that gives rise to second-heart-field-derived regions of the heart and branchiomeric muscles. GO:0046214 enterobactin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046214 enterobactin catabolism|enterobactin degradation|enterobactin breakdown The chemical reactions and pathways resulting in the breakdown of enterobactin, a catechol-derived siderochrome of Enterobacteria; enterobactin (N',N',N''-(2,6,10-trioxo-1,5,9-triacyclodecane-3,7,11-triyl)tris(2,3-dihydroxy)benzamide) is a self-triester of 2,3-dihydroxy-N-benzoyl-L-serine and a product of the shikimate pathway. GO:0046213 methyl ethyl ketone catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046213 methyl ethyl ketone degradation|methyl ethyl ketone breakdown|methyl ethyl ketone catabolism The chemical reactions and pathways resulting in the breakdown of methyl ethyl ketone, a clear, colorless liquid with a fragrant, mint-like odor. GO:0046212 obsolete methyl ethyl ketone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046212 methyl ethyl ketone anabolism|methyl ethyl ketone synthesis|methyl ethyl ketone formation|methyl ethyl ketone biosynthesis|methyl ethyl ketone biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of methyl ethyl ketone, a clear, colorless liquid with a fragrant, mint-like odor. It is used as a solvent and in making plastics, textiles and paints. GO:0046211 (+)-camphor biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046211 (+)-camphor anabolism|(+)-camphor synthesis|(+)-camphor formation|(+)-camphor biosynthesis The chemical reactions and pathways resulting in the formation of (+)-camphor, a bicyclic monoterpene ketone. GO:0046210 nitric oxide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046210 nitric oxide catabolism|nitric oxide degradation|nitric oxide breakdown The chemical reactions and pathways resulting in the breakdown of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water. CHEBI:35300 ortho- and peri-fused polycyclic arene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35300 CHEBI:84276 methyl phenyl(piperidin-2-yl)acetate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84276 GO:0061830 concave side of sperm head biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061830 The concave part of the late spermatid head or spermatozoon head that forms the ventral portion of the head, particularly in some rodent species. CHEBI:84274 (E)-dodec-2-enoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84274 GO:0061832 basal ectoplasmic specialization biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061832 basal ES Testis-specific junction between mature Sertoli cells involved in establishing the blood-testis barrier of the Sertoli cell. GO:0061831 apical ectoplasmic specialization biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061831 apical ES Testis-specific junction between mature spermatids and Sertoli cells at the luminal end of the Sertoli cell. GO:0061834 actin filament branch point biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061834 microfilament branch point The part of an actin filament where the structure forks. CHEBI:35306 9'-cis-neoxanthin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35306 GO:0046219 indolalkylamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046219 indolalkylamine anabolism|indolalkylamine synthesis|indolalkylamine biosynthesis|indolalkylamine formation The chemical reactions and pathways resulting in the formation of indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group. CHEBI:35305 9-cis-violaxanthin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35305 GO:0046218 indolalkylamine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046218 indolalkylamine degradation|indolalkylamine breakdown|indolalkylamine catabolism The chemical reactions and pathways resulting in the breakdown of indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group. GO:0061833 protein localization to tricellular tight junction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061833 A process in which a protein is transported to, or maintained in, a location within a tricellular tight junction. GO:0061836 intranuclear rod biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061836 intranuclear actin rod A macromolecular fiber consisting of actin and cofilin that is formed in the nucleus as a consequence of chemical or mechanical stress conditions. GO:0061835 ventral surface of cell biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061835 The surface of a migrating cell that is in contact with the substratum or cell layer. GO:0061838 CENP-T-W-S-X complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061838 A histone-variant containing protein complex which forms a centromere specific nucleosomal structure, involved in centromeric chromatin organization. GO:0061837 neuropeptide processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061837 Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a neuropeptide precursor. Processing leads to the attainment of the full functional capacity of the neuropeptide. GO:0061839 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0061839 GO:0046220 pyridine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046220 pyridine anabolism|pyridine biosynthesis|pyridine synthesis|pyridine formation The chemical reactions and pathways resulting in the formation of pyridine, a nitrogenous base (C5H5N) obtained from the distillation of bone oil or coal tar, and by the decomposition of certain alkaloids, as a colorless liquid with a peculiar pungent odor. UBERON:0036150 skin appendage follicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0036150 cutaneous appendage follicle|skin follicle|follicle An organ subunit in the skin that gives rise to cutaneous appendage. CHEBI:50912 cardiotoxic agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50912 UBERON:0012141 manual digitopodium region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012141 A digitopodium region that is part of a manus[Obol]. This includes the fingers and metacarpal region, but excludes the carpal region. UBERON:0012140 digitopodium region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012140 acropodium (Wagner) A segment of the autopod consisting of both acropodial region and metapodial region, but excluding the mesopodial/basopodial region. CHEBI:50910 neurotoxin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50910 GO:0046228 2,4,5-trichlorophenoxyacetic acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046228 2,4,5-trichlorophenoxyacetic acid degradation|2,4,5-trichlorophenoxyacetic acid breakdown|2,4,5-trichlorophenoxyacetic acid catabolism The chemical reactions and pathways resulting in the breakdown of 2,4,5-trichlorophenoxyacetic acid, a chlorinated aromatic compound widely used as a herbicide. CHEBI:50916 lipid kinase inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50916 GO:0046227 obsolete 2,4,5-trichlorophenoxyacetic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046227 2,4,5-trichlorophenoxyacetic acid biosynthesis|2,4,5-trichlorophenoxyacetic acid biosynthetic process|2,4,5-trichlorophenoxyacetic acid anabolism|2,4,5-trichlorophenoxyacetic acid synthesis|2,4,5-trichlorophenoxyacetic acid formation OBSOLETE. The chemical reactions and pathways resulting in the formation of 2,4,5-trichlorophenoxyacetic acid, a chlorinated aromatic compound widely used as a herbicide. GO:0046226 coumarin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046226 coumarin catabolism|coumarin degradation|coumarin breakdown The chemical reactions and pathways resulting in the breakdown of coumarins, compounds derived from the phenylacrylic skeleton of cinnamic acids. CHEBI:50914 EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50914 UBERON:0012142 pedal digitopodium region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012142 A digitopodium region that is part of a pes[Obol]. This includes the toes and metatarsal region, but excludes the tarsals region. GO:0046225 bacteriocin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046225 bacteriocin degradation|bacteriocin catabolism|bacteriocin breakdown The chemical reactions and pathways resulting in the breakdown of a bacteriocin, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary. GO:0046224 bacteriocin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046224 bacteriocin metabolism The chemical reactions and pathways involving bacteriocins, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary. GO:0046223 aflatoxin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046223 aflatoxin degradation|aflatoxin breakdown|aflatoxin catabolism The chemical reactions and pathways resulting in the breakdown of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450. CHEBI:50919 antiemetic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50919 GO:0046222 aflatoxin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046222 aflatoxin B metabolic process|aflatoxin B2 metabolic process|aflatoxin B1 metabolic process|aflatoxin metabolism|aflatoxin B1 metabolism|aflatoxin B2 metabolism The chemical reactions and pathways involving aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450. CHEBI:50918 pyrroloquinoline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50918 GO:0046221 pyridine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046221 pyridine catabolism|pyridine degradation|pyridine breakdown The chemical reactions and pathways resulting in the breakdown of pyridine, a nitrogenous base (C5H5N) obtained from the distillation of bone oil or coal tar, and by the decomposition of certain alkaloids, as a colorless liquid with a peculiar pungent odor. GO:0061860 DNA clamp unloader activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061860 Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the opening of the ring structure of the PCNA complex, or any of the related sliding clamp complexes, and their removal from the DNA duplex. GO:0061863 microtubule plus end polymerase biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061863 Catalysis of the transfer of tubulin dimers to the plus end of a microtubule. The reaction is reversable depending on the availability of dimers. GO:0061862 cellular response to differentiation-inducing factor 2 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061862 cellular response to DIF2|cellular response to DIF-2|cellular response to 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one stimulus. UBERON:0012139 segment of autopod biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012139 GO:0061865 polarized secretion of basement membrane proteins in epithelium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061865 The basement membrane constituent secretion in which there is a restriction or targeting of basement membrane proteins for controlled release on the basal side of polarized epithelium. GO:0061864 basement membrane constituent secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061864 The controlled release of molecules that form the basement membrane, including carbohydrates and glycoproteins by a cell. GO:0061867 establishment of mitotic spindle asymmetry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061867 The mitotic spindle organization process by which a mitotic spindle becomes asymmetric either in position or structure. GO:0061866 negative regulation of histone H3-S10 phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061866 Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of one or more phosphate groups to histone H3 on a serine residue at position 10. GO:0046229 obsolete 2-aminobenzenesulfonate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046229 2-aminobenzenesulphonate biosynthetic process|2-aminobenzenesulphonate biosynthesis|2-aminobenzenesulfonate anabolism|2-aminobenzenesulfonate synthesis|2-aminobenzenesulfonate biosynthetic process|2-aminobenzenesulfonate biosynthesis|2-aminobenzenesulfonate formation OBSOLETE. The chemical reactions and pathways resulting in the formation of 2-aminobenzenesulfonate, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines. GO:0061869 regulation of hepatic stellate cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061869 Any process that modulates the frequency, rate or extent of hepatic stellate cell migration. GO:0061868 hepatic stellate cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061868 The orderly movement of a hepatic stellate cell from one site to another. GO:0046231 obsolete carbazole biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046231 carbazole anabolism|carbazole synthesis|carbazole formation|carbazole biosynthetic process|carbazole biosynthesis OBSOLETE. The chemical reactions and pathways resulting in the formation of carbazole, a heterocyclic aromatic compound containing a dibenzopyrrole system that is produced during coal gasification and is present in cigarette smoke. Coal tar produced at high temperature contains an average of 1.5% carbazole. It is used widely in synthesis of dyes, pharmaceuticals, and plastics and is a suspected carcinogen. GO:0046230 2-aminobenzenesulfonate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046230 2-aminobenzenesulfonate catabolism|2-aminobenzenesulphonate catabolic process|2-aminobenzenesulphonate catabolism|2-aminobenzenesulfonate degradation|2-aminobenzenesulfonate breakdown The chemical reactions and pathways resulting in the breakdown of 2-aminobenzenesulfonate, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines. CHEBI:25961 phenanthrenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25961 GO:0046239 phthalate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046239 phthalate degradation|phthalate breakdown|phthalate catabolism The chemical reactions and pathways resulting in the breakdown of phthalate, the anion of phthalic acid. CHEBI:50905 teratogenic agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50905 GO:0046238 obsolete phthalate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046238 phthalate anabolism|phthalate biosynthesis|phthalate biosynthetic process|phthalate synthesis|phthalate formation OBSOLETE. The chemical reactions and pathways resulting in the formation of phthalate, any ester or salt of phthalic acid. CHEBI:50904 allergen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50904 GO:0046237 obsolete phenanthrene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046237 phenanthrene anabolism|phenanthrene synthesis|phenanthrene biosynthesis|phenanthrene biosynthetic process|phenanthrene formation OBSOLETE. The chemical reactions and pathways resulting in the formation of phenanthrene, a tricyclic aromatic hydrocarbon. CHEBI:50903 carcinogenic agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50903 GO:0046236 mandelate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046236 mandelate anabolism|mandelate synthesis|mandelate formation|mandelate biosynthesis The chemical reactions and pathways resulting in the formation of mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic. CHEBI:50902 genotoxin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50902 GO:0046235 gallate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046235 gallic acid biosynthetic process|gallic acid biosynthesis|gallate biosynthesis|gallate anabolism|gallate synthesis|gallate formation The chemical reactions and pathways resulting in the formation of gallate, the anion of gallic acid (3,4,5-trihydroxybenzoic acid). CHEBI:50909 nephrotoxic agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50909 GO:0046234 obsolete fluorene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046234 fluorene biosynthetic process|fluorene biosynthesis|fluorene anabolism|fluorene synthesis|fluorene formation OBSOLETE. The chemical reactions and pathways resulting in the formation of fluorene, a tricyclic polycyclic aromatic hydrocarbon containing a five-membered ring. It is a major component of fossil fuels and their derivatives and is also a by-product of coal-conversion and energy-related industries. It is commonly found in vehicle exhaust emissions, crude oils, motor oils, coal and oil combustion products, waste incineration, and industrial effluents. CHEBI:50908 hepatotoxic agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50908 GO:0046233 obsolete 3-hydroxyphenylacetate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046233 3-hydroxyphenylacetate biosynthesis|3-hydroxyphenylacetate biosynthetic process|3-hydroxyphenylacetate anabolism|3-hydroxyphenylacetate synthesis|3-hydroxyphenylacetate formation OBSOLETE. The chemical reactions and pathways resulting in the formation of 3-hydroxyphenylacetate, 1,3-benzenediol monoacetate, also known as resorcinol monoacetate. GO:0046232 carbazole catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046232 carbazole breakdown|carbazole catabolism|carbazole degradation The chemical reactions and pathways resulting in the breakdown of carbazole, a heterocyclic aromatic compound containing a dibenzopyrrole system that is produced during coal gasification and is present in cigarette smoke. Coal tar produced at high temperature contains an average of 1.5% carbazole. It is used widely in synthesis of dyes, pharmaceuticals, and plastics and is a suspected carcinogen. CHEBI:50906 role biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50906 GO:0061850 growth cone leading edge biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061850 That part of the growth cone which represents the distal part of the structure. CHEBI:84299 1-myristoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84299 GO:0061852 retrograte transporter complex, Golgi to ER biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061852 retrograte receptor complex, Golgi to ER|ERV41-ERV46 retrograde receptor complex|retrograte receptor complex, Golgi to endoplasmic reticulum|retrograte transporter complex, Golgi to endoplasmic reticulum Transporter complex that recognises, binds and returns endoplasmic reticulum (ER) resident proteins that have trafficked to Golgi compartments. Targets proteins lacking the HDEL motif recognised by COPI-coated vesicles. GO:0061851 leading edge of lamellipodium biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061851 That part of the lamellipodium which represents the distal part of the structure. GO:0061854 positive regulation of neuroblast migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061854 Any process that activates or increases the frequency, rate or extent of neuroblast migration. GO:0061853 regulation of neuroblast migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061853 Any process that modulates the frequency, rate or extent of neuroblast migration. GO:0061856 Golgi calcium ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061856 A process in which a calcium ion is transported from one side of a Golgi membrane to the other by means of some agent such as a transporter or pore. GO:0061855 negative regulation of neuroblast migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061855 Any process that stops, prevents, or reduces the frequency, rate or extent of neuroblast migration. GO:0061857 endoplasmic reticulum stress-induced pre-emptive quality control biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061857 ER stress-indiced pre-emptive quality control|ER pQC The response to endoplasimic reticulum stress in which nascent proteins are degraded by attenuation of their translocation into the ER followed by rerouting to the cytosol without cleavage of the signal peptide, and subsequent degradation by the proteasome. CHEBI:84291 organic sulfur anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84291 GO:0046242 obsolete o-xylene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046242 o-xylene anabolism|ortho-xylene biosynthetic process|ortho-xylene biosynthesis|o-xylene synthesis|o-xylene formation|o-xylene biosynthesis|o-xylene biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of o-xylene, (1,2-dimethylbenzene) a colorless, liquid aromatic hydrocarbon. GO:0046241 obsolete m-xylene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046241 m-xylene anabolism|m-xylene synthesis|m-xylene formation|m-xylene biosynthetic process|m-xylene biosynthesis|meta-xylene biosynthesis|meta-xylene biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of m-xylene, 1,3-dimethylbenzene, a colorless, liquid aromatic hydrocarbon. GO:0046240 obsolete xylene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046240 xylene anabolism|xylene synthesis|xylene formation|xylene biosynthesis|xylene biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of xylene, a mixture of three colorless, aromatic hydrocarbon liquids, ortho-, meta- and para-xylene. CHEBI:49900 arsenous acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49900 GO:0046249 alpha-pinene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046249 alpha-pinene degradation|alpha-pinene catabolism|alpha-pinene breakdown The chemical reactions and pathways resulting in the breakdown of alpha-pinene, a monoterpene that may be a significant factor affecting bacterial activities in nature. GO:0046248 alpha-pinene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046248 alpha-pinene biosynthesis|alpha-pinene anabolism|alpha-pinene synthesis|alpha-pinene formation The chemical reactions and pathways resulting in the formation of alpha-pinene, a monoterpene that may be a significant factor affecting bacterial activities in nature. GO:0046247 terpene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046247 terpene degradation|terpene breakdown|terpene catabolism The chemical reactions and pathways resulting in the breakdown of terpenes, any of a large group of hydrocarbons made up of isoprene units. GO:0046246 terpene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046246 terpene anabolism|terpene synthesis|terpene biosynthesis|terpene formation The chemical reactions and pathways resulting in the formation of terpenes, any of a large group of hydrocarbons made up of isoprene units. GO:0046245 obsolete styrene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046245 styrene formation|styrene biosynthesis|styrene biosynthetic process|styrene anabolism|styrene synthesis OBSOLETE. The chemical reactions and pathways resulting in the formation of styrene, an aromatic hydrocarbon liquid used in the manufacture of polystyrene. GO:0046244 salicylic acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046244 salicylic acid degradation|salicylic acid breakdown|salicylic acid catabolism The chemical reactions and pathways resulting in the breakdown of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid. GO:0061881 positive regulation of anterograde axonal transport of mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061881 positive regulation of anterograde axon transport of mitochondria Any process that activates or increasesthe frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse. GO:0046243 obsolete p-xylene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046243 para-xylene biosynthetic process|para-xylene biosynthesis|p-xylene anabolism|p-xylene synthesis|p-xylene formation|p-xylene biosynthesis|p-xylene biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of p-xylene (1,4-dimethylbenzene), a colorless, liquid aromatic hydrocarbon. GO:0061880 regulation of anterograde axonal transport of mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061880 regulation of anterograde axon transport of mitochondria Any process that modulates the frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse. GO:0061883 clathrin-dependent endocytosis involved in vitellogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061883 clathrin-dependent endocytosis involved in yolk formation A clathrin-mediated endocytosis process whereby yolk proteins are internalized and trafficked through the endocytic pathway for yolk deposition. GO:0061882 negative regulation of anterograde axonal transport of mitochondrion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061882 negative regulation of anterograde axon transport of mitochondria Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse. GO:0061885 positive regulation of mini excitatory postsynaptic potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061885 Any process that increases the frequency, rate or extent of mini excitatory postsynaptic potential. Mini excitatory postsynaptic potential is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse. GO:0061884 regulation of mini excitatory postsynaptic potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061884 Any process that modulates the frequency, rate or extent of mini excitatory postsynaptic potential. Mini excitatory postsynaptic potential is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse. GO:0061887 obsolete reproduction of symbiont in host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061887 OBSOLETE. The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms, occurring within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. GO:0061886 negative regulation of mini excitatory postsynaptic potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061886 Any process that decreases the frequency, rate or extent of mini excitatory postsynaptic potential. Mini excitatory postsynaptic potential is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse. GO:0071209 U7 snRNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071209 Interacting selectively and non-covalently with the U7 small nuclear RNA (U7 snRNA). GO:0061889 negative regulation of astrocyte activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061889 Any process that decreases the frequency, rate or extent of astrocyte activation. GO:0071208 histone pre-mRNA DCP binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071208 Interacting selectively and non-covalently with the downstream cleavage product (DCP) generated by histone pre-mRNA 3'-end processing. GO:0071207 histone pre-mRNA stem-loop binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071207 Interacting selectively and non-covalently with a conserved stem-loop structure found in histone pre-mRNAs. GO:0061888 regulation of astrocyte activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061888 Any process that modulates the frequency, rate or extent of astrocyte activation. GO:0071206 establishment of protein localization to juxtaparanode region of axon biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071206 establishment of protein localisation to juxtaparanode region of axon The directed movement of a protein to the juxtaparanode region of an axon. GO:0071205 protein localization to juxtaparanode region of axon biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071205 protein localisation to juxtaparanode region of axon Any process in which a protein is transported to, or maintained at, the juxtaparanode region of an axon. GO:0071204 histone pre-mRNA 3'end processing complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071204 histone 3'end pre-mRNA complex A ribonucleoprotein that binds to specific sites in, and is required for cleavage of, the 3'-end of histone pre-mRNAs. The complex contains the U7 snRNP and additional proteins, including the stem-loop binding protein (SLBP) and the exonuclease 3'hExo/Eri-1. GO:0071203 WASH complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071203 A protein complex that localizes at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization. In human, the WASH complex is composed of F-actin-capping protein subunits alpha and beta, WASH1, FAM21, KIAA1033, KIAA0196 and CCDC53. CHEBI:25935 hydroperoxyl biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25935 GO:0071202 Kv4.3-DPP10 channel complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071202 CORUM:598 Kv4.3-DPPY channel complex A voltage-gated potassium channel complex that contains the peptidase-related protein DPP10 associated with the channel via interaction with the Kv alpha subunit 4.3. GO:0071201 Kv4.3-DPP6 channel complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071201 CORUM:599 Kv4.3-DPPX channel complex A voltage-gated potassium channel complex that contains the peptidase-related protein DPP6 associated with the channel via interaction with the Kv alpha subunit 4.3. GO:0071200 Kv4.2-DPP6 channel complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071200 CORUM:603 Kv4.2-DPPX channel complex A voltage-gated potassium channel complex that contains the peptidase-related protein DPP6 associated with the channel via interaction with the Kv alpha subunit 4.2. GO:0046253 anaerobic toluene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046253 anaerobic toluene anabolism|anaerobic toluene synthesis|anaerobic toluene formation|anaerobic toluene biosynthesis The chemical reactions and pathways resulting in the formation of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products, in the absence of oxygen. CHEBI:25941 peroxynitrite biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_25941 CHEBI:25940 peroxides biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_25940 GO:0046252 toluene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046252 toluene biosynthesis|toluene anabolism|toluene synthesis|toluene formation The chemical reactions and pathways resulting in the formation of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products. GO:0046251 limonene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046251 limonene degradation|limonene breakdown|limonene catabolism The chemical reactions and pathways resulting in the breakdown of limonene (4-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene. GO:0046250 limonene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046250 limonene biosynthesis|limonene formation|limonene anabolism|limonene synthesis The chemical reactions and pathways resulting in the formation of limonene (4-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene. CHEBI:25944 pesticide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25944 UBERON:0012193 phrenic vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012193 The veins that run parallel to the phrenic arteries which include the two superior and two inferior phrenic veins. CHEBI:25942 peroxynitrous acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25942 GO:0046259 obsolete trinitrotoluene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046259 trinitrotoluene synthesis|trinitrotoluene biosynthesis|trinitrotoluene biosynthetic process|trinitrotoluene formation|trinitrotoluene anabolism OBSOLETE. The chemical reactions and pathways resulting in the formation of trinitrotoluene, a methylated benzene molecule with three NO2 groups attached to it. GO:0046258 anaerobic 2,4,6-trinitrotoluene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046258 anaerobic 2,4,6-trinitrotoluene catabolism|anaerobic 2,4,6-trinitrotoluene degradation|anaerobic 2,4,6-trinitrotoluene breakdown The chemical reactions and pathways resulting in the breakdown of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid, in the absence of oxygen. GO:0046257 obsolete anaerobic 2,4,6-trinitrotoluene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046257 anaerobic 2,4,6-trinitrotoluene formation|anaerobic 2,4,6-trinitrotoluene biosynthesis|anaerobic 2,4,6-trinitrotoluene biosynthetic process|anaerobic 2,4,6-trinitrotoluene anabolism|anaerobic 2,4,6-trinitrotoluene synthesis OBSOLETE. The chemical reactions and pathways resulting in the formation of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid, in the absence of oxygen. GO:0046256 2,4,6-trinitrotoluene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046256 2,4,6-trinitrotoluene catabolism|2,4,6-trinitrotoluene degradation|2,4,6-trinitrotoluene breakdown The chemical reactions and pathways resulting in the breakdown of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid. GO:0046255 obsolete 2,4,6-trinitrotoluene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046255 2,4,6-trinitrotoluene anabolism|2,4,6-trinitrotoluene synthesis|2,4,6-trinitrotoluene formation|2,4,6-trinitrotoluene biosynthesis|2,4,6-trinitrotoluene biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene. GO:0061870 positive regulation of hepatic stellate cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061870 Any process that increases the frequency, rate or extent of hepatic stellate cell migration. GO:0046254 anaerobic toluene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046254 MetaCyc:PWY-81 anaerobic toluene degradation|anaerobic toluene catabolism|anaerobic toluene breakdown The chemical reactions and pathways resulting in the breakdown of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products, in the absence of oxygen. GO:0061872 hepatic stellate cell contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061872 The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a hepatic stellate cell. GO:0061871 negative regulation of hepatic stellate cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061871 Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell migration. GO:0061874 positive regulation of hepatic stellate cell contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061874 Any process that activates or increases the frequency, rate or extent of hepatic stellate cell contraction. GO:0061873 regulation of hepatic stellate cell contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061873 Any process that modulates the frequency, rate or extent of hepatic stellate cell contraction. GO:0061875 negative regulation of hepatic stellate cell contraction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061875 Any process that modulates stops, prevents, or reduces the frequency, rate or extent of hepatic stellate cell contraction. GO:0046264 obsolete thiocyanate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046264 thiocyanate anabolism|thiocyanate synthesis|thiocyanate formation|thiocyanate biosynthesis|thiocyanate biosynthetic process OBSOLETE. The chemical reactions and pathways resulting in the formation of thiocyanate, any anion or salt of thiocyanic acid. GO:0071220 cellular response to bacterial lipoprotein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071220 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipoprotein stimulus. GO:0046263 nitrotoluene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046263 nitrotoluene catabolism|nitrotoluene degradation|nitrotoluene breakdown The chemical reactions and pathways resulting in the breakdown of nitrotoluene, any methylbenzene molecule with NO2 group(s) attached. UBERON:0012180 head or neck skin biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012180 A zone of skin that is part of a craniocervical region. GO:0046262 obsolete nitrotoluene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046262 nitrotoluene biosynthetic process|nitrotoluene biosynthesis|nitrotoluene anabolism|nitrotoluene synthesis|nitrotoluene formation OBSOLETE. The chemical reactions and pathways resulting in the formation of nitrotoluene, any methylbenzene molecule with NO2 group(s) attached. GO:0046261 obsolete 4-nitrotoluene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046261 4-nitrotoluene synthesis|4-nitrotoluene formation|4-nitrotoluene anabolism|4NT biosynthetic process|4NT biosynthesis|4-nitrotoluene biosynthetic process|4-nitrotoluene biosynthesis OBSOLETE. The chemical reactions and pathways resulting in the formation of 4-nitrotoluene, 1-methyl-4-nitrobenzene. GO:0046260 trinitrotoluene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046260 trinitrotoluene breakdown|trinitrotoluene catabolism|trinitrotoluene degradation The chemical reactions and pathways resulting in the breakdown of trinitrotoluene, a methylated benzene entity with three NO2 groups attached to it. This includes the explosive TNT, 1-methyl-2,4,6-trinitrobenzene. GO:0046269 toluene-4-sulfonate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046269 toluene-4-sulphonate catabolism|toluene-4-sulfonate degradation|toluene-4-sulfonate breakdown|toluene-4-sulfonate catabolism|toluene-4-sulphonate catabolic process|4-toluenesulfonate catabolism|4-toluenesulfonate catabolic process The chemical reactions and pathways resulting in the breakdown of toluene-4-sulfonate, 4-methylbenzenesulfonate, the anion of sulfonic acid attached to a methylbenzene molecule. CHEBI:11305 10-hydroxycaprate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_11305 GO:0046268 obsolete toluene-4-sulfonate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046268 toluene-4-sulphonate biosynthesis|toluene-4-sulphonate biosynthetic process|toluene-4-sulfonate biosynthetic process|toluene-4-sulfonate biosynthesis|toluene-4-sulfonate anabolism|toluene-4-sulfonate synthesis|toluene-4-sulfonate formation|4-toluenesulfonate biosynthetic process|4-toluenesulfonate biosynthesis OBSOLETE. The chemical reactions and pathways resulting in the formation of toluene-4-sulfonate, 4-methylbenzenesulfonate, the anion of sulfonic acid attached to a methylbenzene molecule. GO:0046267 triethanolamine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046267 triethanolamine degradation|triethanolamine breakdown|triethanolamine catabolism The chemical reactions and pathways resulting in the breakdown of triethanolamine, a combustible, hygroscopic, colorless liquid commonly used in dry-cleaning solutions, cosmetics, detergents, textile processing, wool scouring, and as a corrosion inhibitor and pharmaceutical alkalizing agent. GO:0046266 obsolete triethanolamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046266 triethanolamine synthesis|triethanolamine biosynthesis|triethanolamine biosynthetic process|triethanolamine formation|triethanolamine anabolism OBSOLETE. The chemical reactions and pathways resulting in the formation of triethanolamine, a combustible, hygroscopic, colorless liquid commonly used in dry-cleaning solutions, cosmetics, detergents, textile processing, wool scouring, and as a corrosion inhibitor and pharmaceutical alkalizing agent. GO:0046265 thiocyanate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046265 thiocyanate degradation|thiocyanate catabolism|thiocyanate breakdown The chemical reactions and pathways resulting in the breakdown of thiocyanate, any anion of thiocyanic acid. CHEBI:11302 10-desacetyltaxuyunnanin C biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_11302 GO:0071229 cellular response to acid chemical biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0071229 cellular response to acid anion|cellular response to acid|cellular response to oxoanion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of the dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form. GO:0071228 cellular response to tumor cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071228 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a tumor cell. GO:0071227 cellular response to molecule of oomycetes origin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071227 cellular response to oomycetes associated molecule Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of oomycetes origin. CHEBI:25914 peptidyl-amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25914 GO:0071226 cellular response to molecule of fungal origin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071226 cellular response to fungus associated molecule Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of fungal origin such as chito-octamer oligosaccharide. GO:0071225 cellular response to muramyl dipeptide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071225 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muramyl dipeptide stimulus. Muramyl dipeptide is derived from peptidoglycan. GO:0071224 cellular response to peptidoglycan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071224 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidoglycan stimulus. Peptidoglycan is a bacterial cell wall macromolecule. GO:0071223 cellular response to lipoteichoic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071223 cellular response to LTA Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoteichoic acid stimulus; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor. GO:0071222 cellular response to lipopolysaccharide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071222 cellular response to LPS|cellular response to endotoxin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria. GO:0071221 cellular response to bacterial lipopeptide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071221 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipopeptide stimulus. GO:0046275 flavonoid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046275 flavonoid degradation|flavonoid breakdown|flavonoid catabolism The chemical reactions and pathways resulting in the breakdown of flavonoids, a group of phenolic derivatives containing a flavan skeleton. GO:0046274 lignin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046274 lignin degradation|lignin breakdown|lignin catabolism The chemical reactions and pathways resulting in the breakdown of lignins, a class of polymers of phenylpropanoid units. GO:0046273 lignan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046273 lignan catabolism|lignan degradation|lignan breakdown The chemical reactions and pathways resulting in the breakdown of lignans, any member of a class of plant metabolites related to lignins. Lignans are usually found as phenylpropanoid dimers in which the phenylpropanoid units are linked tail to tail and thus having a 2,3 dibenzylbutane skeleton, but higher oligomers can also exist. GO:0046272 stilbene catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046272 stilbene catabolism|stilbene degradation|stilbene breakdown The chemical reactions and pathways resulting in the breakdown of stilbenes, a class of polyketide compounds formed from cinnamic acid and three molecules of malonyl CoA. GO:0046271 phenylpropanoid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046271 phenylpropanoid degradation|phenylpropanoid catabolism|phenylpropanoid breakdown The chemical reactions and pathways resulting in the breakdown of aromatic derivatives of trans-cinnamic acid. GO:1900107 regulation of nodal signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900107 regulation of nodal signalling pathway|regulation of nodal signaling Any process that modulates the frequency, rate or extent of nodal signaling pathway. GO:1900106 positive regulation of hyaluranon cable assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900106 up regulation of HA cable assembly|upregulation of hyaluranon cable assembly|positive regulation of HA cable assembly|activation of HA cable assembly|up regulation of hyaluranon cable assembly|up-regulation of HA cable assembly|activation of hyaluranon cable assembly|upregulation of HA cable assembly|up-regulation of hyaluranon cable assembly Any process that activates or increases the frequency, rate or extent of hyaluranon cable assembly. GO:0046270 obsolete 4-toluenecarboxylate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046270 4-toluenecarboxylate formation|4-toluenecarboxylate biosynthetic process|4-toluenecarboxylate biosynthesis|4-toluenecarboxylate anabolism|4-toluenecarboxylate synthesis OBSOLETE. The chemical reactions and pathways resulting in the formation of 4-toluenecarboxylate, 4-methylbenzenecarboxylate, the anion of carboxylic acid attached to a methylbenzene molecule. GO:1900109 regulation of histone H3-K9 dimethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900109 regulation of histone lysine H3 K9 dimethylation|regulation of histone H3 K9 dimethylation Any process that modulates the frequency, rate or extent of histone H3-K9 dimethylation. UBERON:0012172 stomach primordium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012172 stomach endoderm A primordium that has the potential to develop into a stomach. CHEBI:25921 peptidyl-glycine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25921 GO:1900108 negative regulation of nodal signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900108 downregulation of nodal signaling pathway|down regulation of nodal signaling|down-regulation of nodal signaling pathway|downregulation of nodal signaling|inhibition of nodal signaling pathway|negative regulation of nodal signaling|down-regulation of nodal signaling|negative regulation of nodal signalling pathway|inhibition of nodal signaling|down regulation of nodal signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of nodal signaling pathway. CHEBI:25920 peptidyl-glycine cholesteryl ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25920 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900103 activation of SREBP-mediated signalling pathway|up regulation of endoplasmic reticulum unfolded protein response|upregulation of erUPR|activation of endoplasmic reticulum unfolded protein response|up-regulation of ER unfolded protein response|up-regulation of SREBP-mediated signalling pathway|up regulation of erUPR|activation of ER unfolded protein response|positive regulation of erUPR|up-regulation of endoplasmic reticulum unfolded protein response|upregulation of SREBP-mediated signalling pathway|positive regulation of ER unfolded protein response|activation of erUPR|up regulation of ER unfolded protein response|upregulation of endoplasmic reticulum unfolded protein response|up-regulation of erUPR|up regulation of SREBP-mediated signalling pathway|positive regulation of SREBP-mediated signalling pathway|upregulation of ER unfolded protein response Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum unfolded protein response. GO:1900102 negative regulation of endoplasmic reticulum unfolded protein response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900102 inhibition of ER unfolded protein response|down regulation of erUPR|down-regulation of endoplasmic reticulum unfolded protein response|downregulation of erUPR|inhibition of SREBP-mediated signalling pathway|negative regulation of ER unfolded protein response|down-regulation of ER unfolded protein response|inhibition of endoplasmic reticulum unfolded protein response|negative regulation of erUPR|down-regulation of erUPR|down regulation of SREBP-mediated signalling pathway|downregulation of ER unfolded protein response|downregulation of SREBP-mediated signalling pathway|down regulation of ER unfolded protein response|down regulation of endoplasmic reticulum unfolded protein response|inhibition of erUPR|downregulation of endoplasmic reticulum unfolded protein response|down-regulation of SREBP-mediated signalling pathway|negative regulation of SREBP-mediated signalling pathway Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum unfolded protein response. GO:1900105 negative regulation of hyaluranon cable assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900105 downregulation of HA cable assembly|down regulation of hyaluranon cable assembly|down-regulation of HA cable assembly|negative regulation of HA cable assembly|downregulation of hyaluranon cable assembly|inhibition of HA cable assembly|down-regulation of hyaluranon cable assembly|down regulation of HA cable assembly|inhibition of hyaluranon cable assembly Any process that stops, prevents or reduces the frequency, rate or extent of hyaluranon cable assembly. GO:1900104 regulation of hyaluranon cable assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900104 regulation of HA cable assembly Any process that modulates the frequency, rate or extent of hyaluranon cable assembly. UBERON:0012175 acoustico-facial VII-VIII ganglion complex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0012175 facio-acoustic ganglion complex|acousticofacial ganglion|facio-acoustic VII-VIII ganglion complex|facio-acoustic ganglion|facio-acoustic ganglion complex VII-VIII GO:0046279 3,4-dihydroxybenzoate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046279 protocatechuate biosynthetic process|protocatechuate biosynthesis|protocatechuate anabolism|protocatechuate synthesis|protocatechuate formation The chemical reactions and pathways resulting in the formation of 3,4-dihydroxybenzoate. GO:0061890 positive regulation of astrocyte activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061890 Any process that increases the frequency, rate or extent of astrocyte activation. GO:0046278 3,4-dihydroxybenzoate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046278 protocatechuate metabolism|protocatechuate metabolic process The chemical reactions and pathways involving protocatechuate, the anion of protocatechuic acid (3,4-dihydroxybenzoic acid). GO:1900101 regulation of endoplasmic reticulum unfolded protein response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900101 regulation of erUPR|regulation of SREBP-mediated signalling pathway|regulation of ER unfolded protein response Any process that modulates the frequency, rate or extent of endoplasmic reticulum unfolded protein response. GO:0046277 methylgallate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046277 methylgallate biosynthesis|methylgallate anabolism|methylgallate synthesis|methylgallate formation The chemical reactions and pathways resulting in the formation of methylgallate, trihydroxymethylbenzoate, the anion of methylgallic acid. GO:0061891 calcium ion sensor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061891 Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of calcium ions (Ca2+). GO:0046276 methylgallate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046276 MetaCyc:METHYLGALLATE-DEGRADATION-PWY methylgallate degradation|methylgallate breakdown|methylgallate catabolism The chemical reactions and pathways resulting in the breakdown of methylgallate, trihydroxymethylbenzoate, the anion of methylgallic acid. GO:1900100 positive regulation of plasma cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900100 upregulation of plasma cell differentiation|activation of plasma cell development|up-regulation of plasma cell development|up regulation of plasma cell differentiation|activation of plasma cell differentiation|upregulation of plasma cell development|up-regulation of plasma cell differentiation|up regulation of plasma cell development|positive regulation of plasma cell development Any process that activates or increases the frequency, rate or extent of plasma cell differentiation. GO:0061896 all-trans retinol 3,4-desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061896 RHEA:50292 Catalysis of the reaction: all-trans-retinol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = all-trans-3,4-didehydro retinol + 2 H2O + 2 oxidized [adrenodoxin]. GO:0061898 all-trans retinoic acid 3,4-desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061898 Catalysis of the reaction: all-trans-retinoic acid + 2 H(+) + O2 + 2 reduced [adrenodoxin] = all-trans-3,4-didehydro retinoic acid + 2 H2O + 2 oxidized [adrenodoxin]. GO:0061897 all-trans retinal 3,4-desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061897 Catalysis of the reaction: all-trans-retinal + 2 H(+) + O2 + 2 reduced [adrenodoxin] = all-trans-3,4-didehydro retinal + 2 H2O + 2 oxidized [adrenodoxin]. GO:0071219 cellular response to molecule of bacterial origin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071219 cellular response to bacteria associated molecule|cellular response to bacterium associated molecule|cellular response to bacterial associated molecule Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin. GO:0071218 cellular response to misfolded protein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071218 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a misfolded protein stimulus. GO:0061899 11-cis-retinal 3,4-desaturase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061899 Catalysis of the reaction: 11-cis-retinal + 2 H(+) + O2 + 2 reduced [adrenodoxin] = 11-cis-3,4-didehydro-retinal + 2 H2O + 2 oxidized [adrenodoxin]. GO:0071217 cellular response to external biotic stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071217 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things. GO:0071216 cellular response to biotic stimulus biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0071216 cellular response to biotic stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism. GO:0071215 cellular response to abscisic acid stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071215 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus. GO:0071214 cellular response to abiotic stimulus biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0071214 cellular response to abiotic stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus. GO:0071213 cellular response to 1-aminocyclopropane-1-carboxylic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071213 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-aminocyclopropane-1-carboxylic acid stimulus. GO:0071212 subsynaptic reticulum biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071212 SSR An elaborate tubulolamellar membrane system that underlies the postsynaptic cell membrane. GO:0071211 protein targeting to vacuole involved in autophagy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071211 protein targeting to autophagosome The process of directing proteins towards the vacuole using signals contained within the protein, occurring as part of autophagy, the process in which cells digest parts of their own cytoplasm. GO:0071210 protein insertion into membrane raft biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071210 establishment of protein localization to membrane raft The process in which a protein is incorporated into a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. CHEBI:74864 ribose derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74864 CHEBI:132924 sulfoglycolithocholate anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132924 CHEBI:35256 nucleotide-glycopeptide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35256 PR:000035716 ubiquitin (RPS27A) biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000035716 RPS27A/Clv:ubiq A ubiquitin-40S ribosomal protein S27a that has been processed by proteolytic cleavage. This form is the N-terminal region consisting of the Ubiquitin (Pfam:PF00240) domain. Example: UniProtKB:P62979, 1-76. CHEBI:35258 glyco-amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35258 CHEBI:35257 UDP-glycopeptide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35257 CHEBI:35259 benzofurans biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35259 UBERON:0002401 visceral pleura biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002401 pleura visceralis (pulmonalis)|lung pleura|pulmonary pleura|lung mesothelium|pleura visceralis|pulmonary visceral pleura|pleura pulmonalis The inner serous membrane of the pulmonary pleural. The visceral pleura lines the lungs. UBERON:0002400 parietal pleura biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002400 pleura parietalis The outer serous membrane of the pulmonary pleural. UBERON:0002402 pleural cavity biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002402 cavitum pleurale|cavitas pleuralis|cavitum pleuralae The fluid-filled cavity that lies between the visceral and parietal pleurae. CHEBI:50893 azaarene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50893 CHEBI:35252 dTDP-L-mannose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35252 CHEBI:59226 N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59226 CHEBI:35251 dTDP-mannose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35251 CHEBI:35254 dTDP-L-talose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35254 CHEBI:35253 dTDP-talose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35253 CHEBI:50887 haloarene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50887 CHEBI:132939 ethylmalonate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132939 CHEBI:132938 ethylmalonate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132938 CHEBI:35267 quaternary ammonium ion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35267 CHEBI:35266 L-2-succinylamino-6-oxoheptanedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35266 CHEBI:35269 N-glycosyl amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35269 CHEBI:59210 alpha-Neup5Ac-(2->8)-alpha-Neup5Ac-(2->3)-beta-D-Galp-(1->4)-beta-D-Glcp biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59210 CHEBI:60239 beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60239 CHEBI:59216 beta-D-Galp-(1->3)-beta-D-GlcpNAc-(1->4)-beta-D-Galp-(1->4)-beta-D-Glcp biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59216 CHEBI:35262 UDP-amino sugar biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35262 CHEBI:35265 N-phospho-D-lombricine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35265 CHEBI:132908 5(S)-hydroperoxy-18(R)-hydroxy-(6E,8Z,11Z,14Z,16E)-icosapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132908 CHEBI:132909 5(S),6(S)-epoxy-18(R)-hydroxy-(7E,9E,11Z,14Z,16E)-icosapentaenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132909 CHEBI:84209 L-selenocysteine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84209 CHEBI:84208 selenocysteine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84208 CHEBI:84207 16-hydroxyhexadecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84207 CHEBI:84206 5-formyl-2-furoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84206 CHEBI:84205 15-hydroxypentadecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84205 CHEBI:84204 omega-hydroxy fatty acyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84204 CHEBI:60240 divalent metal cation biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60240 CHEBI:132906 (-)-Tau-muurolol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132906 CHEBI:84203 15-hydroxypentadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84203 CHEBI:60242 monovalent inorganic cation biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60242 CHEBI:49883 tetra-mu3-sulfido-tetrairon biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49883 CHEBI:84202 12-hydroxyoctadecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84202 CHEBI:60245 inositol phosphoceramide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60245 CHEBI:84201 12-hydroxyoctadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84201 CHEBI:35233 tungsten coordination entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35233 CL:0002088 interstitial cell of Cajal biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002088 intestinal pacemaker cell|ICC This is a cell found in the gastrointestinal tract of mammals and serves as a pacemaker that triggers gut contraction. ICCs mediate inputs from the enteric nervous system to smooth muscle cells and are thought to be the cells from which gastrointestinal stromal tumors (GISTs) arise. CHEBI:35236 D-cysteine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35236 CHEBI:60247 silver ion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60247 CHEBI:35235 L-cysteine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35235 CHEBI:60249 lead ion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60249 CHEBI:35238 amino acid zwitterion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35238 CHEBI:60248 nickel ion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60248 CHEBI:35237 cysteine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35237 CHEBI:35239 ADP-sugar biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35239 CL:0002085 tanycyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002085 stretch cell Specialized elongated ventricular ependymal cell that has processes that extend to the outer, or pial, surface of the CNS. Resemble spongioblasts seen in developing brain. Found in the adult brain in the third ventricle, cerebral aqueduct, spinal canal and floor of the fourth ventricle. CHEBI:35230 fossil fuel biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35230 CHEBI:50871 valerate ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50871 CHEBI:74882 5-(carboxymethyl)uridine 5'-monophosphate(2-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74882 CL:0002087 nongranular leukocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002087 agranular leukocyte A leukocyte that lacks granules. CHEBI:59203 straight-chain fatty acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59203 CL:0002086 specialized cardiac myocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002086 A cardiac myocyte that is an excitable cells in the myocardium, specifically in the conducting system of heart. CHEBI:59202 straight-chain fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59202 CHEBI:74897 1-oleoyl-2-arachidonoyl-sn-glycero-3-phospho-L-serine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74897 CHEBI:50864 insulin-sensitizing drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50864 CHEBI:74896 3'-end ribonucleotide(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74896 CHEBI:74898 3'-end 2'-O-methylribonucleotide(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74898 CHEBI:60250 selenium ion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60250 CHEBI:84217 [5-(aminomethyl)-3-furyl]methyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84217 CHEBI:60252 lead cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60252 CHEBI:60251 guanidinium ion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60251 CHEBI:49870 antimonous acid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49870 CHEBI:84215 gamma-glutamyltyramine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84215 CHEBI:132917 2-isopropylmalate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132917 CHEBI:60254 (3R)-3-(tert-butylcarbamoyl)piperazin-1-ium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60254 CHEBI:84214 9-decenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84214 CHEBI:60253 silver cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60253 CHEBI:84213 4-(phosphooxymethyl)-2-furancarboxaldehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84213 CHEBI:60256 (4R)-N-(2,3-dihydroxytetracosanoyl)-4-hydroxysphinganine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60256 CHEBI:84212 furan-2,5-dicarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84212 CHEBI:35245 GDP-galactose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35245 CHEBI:35244 nucleotide-oligosaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35244 CHEBI:60255 puromycin(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60255 CHEBI:84211 5-(dihydroxymethyl)-2-furoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84211 CHEBI:35247 D-serine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35247 CHEBI:60258 EC 3.4.* (hydrolases acting on peptide bond) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60258 CHEBI:60257 N(omega)-methyl-L-arginine zwitterion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60257 CHEBI:35248 dTDP-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35248 CL:0002092 bone marrow cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002092 A cell found in the bone marrow. This can include fibroblasts, macrophages, adipocytes, osteoblasts, osteoclasts, endothelial cells and hematopoietic cells. CHEBI:74890 N(1)-methylpseudouridine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74890 CHEBI:35241 nucleotide-carbohydrate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35241 CHEBI:50860 organic molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50860 CHEBI:74892 1-oleoyl-2-linoleoyl-sn-glycero-3-phospho-L-serine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74892 CHEBI:35240 nucleotide-alditol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35240 CHEBI:35243 serine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35243 CL:0002098 regular cardiac myocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002098 regular cardiac muscle cell|regular cardiac muscle fiber A cardiac myocyte that is connected to other cardiac myocytes by transverse intercalated discs (GO:0014704) at a regular interval. CHEBI:74894 N(3)-methylcytidine 5'-monophosphate(1-) residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74894 CL:0002097 cortical cell of adrenal gland biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002097 adrenal cortex cell|adrenocortical cell A cell of the adrenal cortex. Cell types include those that synthesize and secrete chemical derivatives (steroids) of cholesterol. CHEBI:35242 CDP-D-glucose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35242 CHEBI:25897 pentenoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25897 CHEBI:50857 anti-allergic agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50857 UBERON:0002437 cerebral hemisphere white matter biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002437 cerebral white matter|region of cerebral white matter|substantia medullaris cerebri|cerebral hemisphere white matter|white matter structure of cerebral hemisphere|hemisphere white matter White matter that is part of a cerebral hemisphere. CHEBI:25899 pentitol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25899 CHEBI:50855 antiatherogenic agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50855 CHEBI:25898 pentitol phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25898 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046404 MetaCyc:POLYNUCLEOTIDE-5-HYDROXYL-KINASE-RXN|RHEA:15669|EC:2.7.1.78|KEGG_REACTION:R03840 ATP-dependent DNA 5'-hydroxyl-kinase activity|ATP-dependent polynucleotide 5'-hydroxyl-kinase activity|ATP-dependent DNA kinase activity|ATP:5'-dephosphopolydeoxyribonucleotide 5'-phosphotransferase activity Catalysis of the reaction: ATP + 5'-dephospho-DNA = ADP + 5'-phospho-DNA. GO:0046403 polynucleotide 3'-phosphatase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046403 Reactome:R-HSA-5649705|EC:3.1.3.32|MetaCyc:POLYNUCLEOTIDE-3-PHOSPHATASE-RXN|RHEA:14113 polynucleotide 3'-phosphohydrolase activity|2'(3')-polynucleotidase activity|5'-polynucleotidekinase 3'-phosphatase activity|DNA 3'-phosphatase activity|deoxyribonucleate 3'-phosphatase activity Catalysis of the reaction: 3'-phosphopolynucleotide + H2O = a polynucleotide + phosphate. Hydrolyzes the free 3'-phosphate resulting from single strand breaks in DNA due to oxidative damage. CHEBI:35219 plant growth retardant biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35219 GO:0046402 O antigen metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046402 O antigen metabolism The chemical reactions and pathways involving the O side chain of a lipopolysaccharide, which determines the antigenic specificity of the organism. It is made up of about 50 repeating units of a branched tetrasaccharide. CHEBI:60260 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60260 GO:0046401 lipopolysaccharide core region metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046401 lipopolysaccharide core region metabolism|LPS core region metabolic process The chemical reactions and pathways resulting in the formation of the core region of bacterial lipopolysaccharides, which contains ten saccharide residues. The structure of this core oligosaccharide appears to be similar in closely related bacterial strains. CHEBI:50858 corticosteroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50858 GO:0046400 keto-3-deoxy-D-manno-octulosonic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046400 KDO metabolic process|keto-3-deoxy-D-manno-octulosonic acid metabolism|KDO metabolism|ketodeoxyoctanoate metabolic process The chemical reactions and pathways involving keto-3-deoxy-D-manno-octulosonic acid, an acidic sugar present in lipopolysaccharides of the outer membranes of some Gram-negative bacteria. CHEBI:25892 pentanone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25892 CHEBI:60267 N(omega)-(ADP-D-ribosyl)-L-arginine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60267 CL:0002067 type A enteroendocrine cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002067 An enteroendocrine cell that produces glucagon. GO:0046409 p-coumarate 3-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046409 cytochrome P450 CYP98A3 Catalysis of the reaction: shikimate or quinate ester of p-coumaric acid + NADPH + H+ + O2 = caffeic acid conjugate (caffeoyl shikimic acid or chlorogenic acid) + H2O + NADP+. CL:0002068 Purkinje myocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002068 Purkinje cell fiber|Purkinje muscle cell|myocytus conducens cardiacus Specialized cardiac myocyte that is subendocardially interspersed with the regular cardiac muscle cell. They are uninucleate cylindrical cells, associated end-to-end in long rows, continue from the node to the atrioventricular bundle; relatively short compared to ordinary myocytes but are nearly twice their diameter. CHEBI:35213 cyclodepsipeptide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35213 CHEBI:60268 phosphonatoformate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60268 GO:0046408 chlorophyll synthetase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046408 KEGG_REACTION:R06284|MetaCyc:RXN1F-66|RHEA:17317|EC:2.5.1.62 chlorophyllide-a:phytyl-diphosphate phytyltransferase activity|chlorophyll synthase activity Catalysis of the reaction: chlorophyllide a + 2 H(+) + phytyl diphosphate = chlorophyll a + diphosphate. GO:0046407 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046407 GO:0046406 magnesium protoporphyrin IX methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046406 MetaCyc:RXN-MG-PROTOPORPHYRIN-METHYLESTER-SYN|RHEA:17809|EC:2.1.1.11|KEGG_REACTION:R04237 Mg-protoporphyrin IX methyltransferase activity|S-adenosyl-L-methionine:magnesium-protoporphyrin O-methyltransferase activity|S-adenosyl-L-methionine:Mg protoporphyrin methyltransferase activity|S-adenosyl-L-methionine:magnesium-protoporphyrin-IX O-methyltransferase activity|S-adenosylmethioninemagnesium protoporphyrin methyltransferase activity|(-)-S-adenosyl-L-methionine:magnesium-protoporphyrin IX methyltransferase activity|magnesium-protoporphyrin O-methyltransferase activity|S-adenosylmethionine-magnesium protoporphyrin methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine(1+) + magnesium protoporphyrin IX = S-adenosyl-L-homocysteine + H(+) + magnesium protoporphyrin IX 13-monomethyl ester. CHEBI:35218 anthocyanin cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35218 GO:0046405 glycerol dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046405 MetaCyc:GLYCEROL-DEHYDRATASE-RXN|EC:4.2.1.30|RHEA:19765 glycerol dehydrase activity|glycerol hydro-lyase (3-hydroxypropanal-forming)|glycerol hydro-lyase activity Catalysis of the reaction: glycerol = 3-hydroxypropanal + H2O. CHEBI:35217 alkaline earth coordination entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35217 UBERON:0002444 lens fiber biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002444 fibrae lentis|lens fibre|lens fibers set|lens fibers|lens fibres|set of lens fibers A region of the lens consisting of packed elongated enucleate cells packed with crystallin UBERON:0002446 patella biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002446 knee cap|knee bone|patella A large sesamoid bone found in the distal femur/proximal tibial region of the hindlimb of tetrapods. The patella is the attachment site for proximal hindlimb tendons.[PHENOSCAPE:ad] CL:0002060 melanophage biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002060 A melanin-containing macrophage that obtains the pigment by phagocytosis of melanosomes. CL:0002063 type II pneumocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002063 great alveolar cell|type II alveolocyte|type 2 alveolar epithelial cell|type II alveolar cell|AT2|lung type 2 cell|granular pneumocyte|cuboidal type II cell|lung type II cell|TII|ATII|type 2 alveolocyte|type 2 pneumocyte|type II alveolar epithelial cell A type II pneumocyte is a pneumocyte that modulates the fluid surrounding the alveolar epithelium by secreting and recycling surfactants. This cell type also contributes to tissue repair and can differentiate after injury into a type I pneumocyte. Thicker than squamous alveolar cells, have a rounded apical surface that projects above the level of surrounding epithelium. The free surface is covered by short microvilli. CL:0002062 type I pneumocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002062 type I alveolar epithelial cells|squamous alveolar cell|pulmonary alveolar type I cell|AT1|lung type 1 cells|membranous pneumocytes|ATI|type I alveolar cells|small alveolar cells|squamous alveolar lining cell|type 1 alveolar epithelial cells|type 1 pneumocyte A type I pneumocyte is a flattened, branched pneumocyte that covers more than 98% of the alveolar surface. This large cell has thin (50-100 nm) cytoplasmic extensions to form the air-blood barrier essential for normal gas exchange. UBERON:0002443 choroidal blood vessel biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002443 set of choroid blood vessels|blood vessel of posterior uvea|blood vessel of choroid coat|vasa sanguinea choroideae|choroid coat blood vessel|choroidea blood vessel|posterior uvea blood vessel|blood vessel of choroid|choroid blood vessels set|choroid blood vessel|blood vessel of choroidea|choroid blood vessels A blood vessel that is part of a choroid [Automatically generated definition]. UBERON:0002442 axillary nerve trunk biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002442 circumflex nerve trunk|trunk of right axillary nerve|right axillary neural trunk CHEBI:50846 immunomodulator biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50846 UBERON:0002427 arm skin biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002427 skin of arm|brachial region skin A zone of skin that is part of an arm [Automatically generated definition]. UBERON:0002426 chest muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002426 muscle organ of anterolateral part of thorax|muscle organ of chest|muscle organ of front of thorax|anterolateral part of thorax muscle organ|anterior thoracic region muscle organ|muscle of thorax|muscle organ of anterior thoracic region|musculus thoracicus|front of thorax muscle organ|chest muscle organ|thoracic muscle Any muscle organ that is part of a chest [Automatically generated definition]. UBERON:0002429 cervical lymph node biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002429 lymph node of neck Cervical lymph nodes are lymph nodes found in the neck. [WP,unvetted]. UBERON:0002428 limb bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002428 bone of extremity|bone of limb|free limb bone A bone that is part of a limb [Automatically generated definition]. GO:0046415 urate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046415 urate metabolism The chemical reactions and pathways involving urate, the anion of uric acid, 2,6,8-trioxypurine, the end product of purine metabolism in certain mammals and the main excretory product in uricotelic animals. CHEBI:60270 caesium ion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60270 GO:0046414 organomercury biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046414 organomercury anabolism|organomercury synthesis|organomercury formation|organomercury biosynthesis The chemical reactions and pathways resulting in the formation of organomercury compounds, any organic compound containing a mercury atom. GO:0046413 organomercury catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046413 organomercury degradation|organomercury catabolism|organomercury breakdown The chemical reactions and pathways resulting in the breakdown of organomercury compounds, any organic compound containing a mercury atom. CHEBI:60272 aluminium ion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60272 CHEBI:50847 immunological adjuvant biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50847 GO:0046412 phenylmercury acetate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046412 phenylmercury acetate metabolism The chemical reactions and pathways involving phenylmercury acetate, an organomercurial compound composed of a mercury atom attached to a benzene ring and an acetate group. CHEBI:60271 tellurium ion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60271 GO:0046411 2-keto-3-deoxygluconate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046411 2-keto-3-deoxygluconate transport The process in which 2-keto-3-deoxygluconate is transported across a lipid bilayer, from one side of a membrane to the other. CHEBI:60274 1,2-dicaproyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60274 CHEBI:84238 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84238 GO:0046410 obsolete 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046410 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity OBSOLETE. Catalysis of the reaction: 2-oxoglutarate + isochorismate = 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate + pyruvate + CO2. CHEBI:60273 1,2-dilauroyl-sn-glycero-3-phosphocholine(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60273 CHEBI:35223 catalyst biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35223 CL:0002078 meso-epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002078 epithelial mesenchymal cell Epithelial cell derived from mesoderm or mesenchyme. CHEBI:84234 1-oleoyl-2-stearoyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84234 CL:0002077 ecto-epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002077 An epithelial cell derived from ectoderm. CHEBI:35222 inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35222 CHEBI:35225 buffer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35225 CHEBI:35224 effector biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35224 GO:0046419 octopine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046419 octopine metabolism The chemical reactions and pathways involving octopine, (N-(1-carboxy-4-guanidinobutyl)-L-alanine), an amino acid derived opine. CHEBI:35227 4-nitrotoluene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35227 GO:0046418 nopaline metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046418 nopaline metabolism The chemical reactions and pathways involving nopaline, (N-(I-carboxy-4-guanidinobutyl)glutamic acid), a rare amino-acid derivative. GO:0046417 chorismate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046417 chorismate metabolism The chemical reactions and pathways involving chorismate, the anion of (3R-trans)-3-((1-carboxyethenyl)oxy)-4-hydroxy-1,5-cyclohexadiene-1-carboxylic acid. GO:0046416 D-amino acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046416 D-amino acid metabolism The chemical reactions and pathways involving D-amino acids, the D-enantiomers of amino acids. CL:0002072 nodal myocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002072 P cell|myocytus nodalis|pacemaker cell|cardiac pacemaker cell A specialized cardiac myocyte in the sinoatrial and atrioventricular nodes. The cell is slender and fusiform confined to the nodal center, circumferentially arranged around the nodal artery. UBERON:0002435 striatum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002435 dorsal striatum|corpus striatum (Zilles)|caudate putamen|striatum|striatum of neuraxis|neostriatum|striated nucleus|corpus striatum|neuraxis striatum|striate nucleus A region of the forebrain consisting of the caudate nucleus, putamen and fundus striati.[GO]. CL:0002071 enterocyte of epithelium of large intestine biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002071 columnar cell|vacuolar absorptive cell|columnar cell of the colon Columnar cell which populate the epithelium of large intestine and absorb water. This cell is the most numerous of the epithelial cell types in the large intestine; bear apical microvilli, contain secretory granules in their apical cytoplasm; secretion appears to be largely mucins, but is also rich in antibodies of the IgA type. CHEBI:11230 1-acylglycerophosphocholine(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_11230 CHEBI:35221 antimetabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35221 CL:0002076 endo-epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002076 An epithelial cell derived from endoderm. UBERON:0002419 skin gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002419 skin glands set|skin glands|glandulae cutis|set of skin glands A gland that is part of a skin of body [Automatically generated definition]. CHEBI:50830 fluorinated steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50830 CHEBI:25872 pentacyclic triterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25872 UBERON:0002416 integumental system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002416 body surface|integumentary system|surface|dermal system|organism surface|external covering of organism|integumentum commune Connected anatomical system that forms a barrier between an animal and its environment. In vertebrates, the integumental system consists of the epidermis, dermis plus associated glands and adnexa such as hair and scales. In invertebrates, the integumental system may include cuticle. CHEBI:25879 pentaerythritol tetranitrate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_25879 UBERON:0002415 tail biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002415 caudal subdivision An external caudal extension of the body. In chordates, the tail is post-anal, in other animals the anus ends in the tail CHEBI:25878 pentaerythritol nitrate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25878 UBERON:0002418 cartilage tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002418 cartilage tissue|cartilaginous tissue|chondrogenic tissue|cartilage|portion of cartilage tissue|cartilages Skeletal tissue that is avascular, rich in glycosaminoglycans (GAGs) and typically includes chondrocytes within isolated lacunae. Cartilage tissue is deposited by chondroblasts. CHEBI:25876 pentadienoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25876 UBERON:0002417 abdominal segment of trunk biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002417 lumbar region|lower body|abdomen/pelvis/perineum|lower trunk The abdominal segment of the torso. GO:0046426 negative regulation of receptor signaling pathway via JAK-STAT biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046426 negative regulation of STAT protein nuclear translocation|down-regulation of JAK-STAT cascade|downregulation of JAK-STAT cascade|down regulation of JAK-STAT cascade|inhibition of JAK-STAT cascade|negative regulation of STAT protein import into nucleus Any process that stops, prevents, or reduces the frequency, rate or extent of a receptor signaling pathway via JAK-STAT. GO:0046425 regulation of receptor signaling pathway via JAK-STAT biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046425 regulation of STAT protein import into nucleus|regulation of STAT protein nuclear translocation|STAT protein import into nucleus Any process that modulates the frequency, rate or extent of receptor signaling via JAK-STAT. GO:0046424 ferulate 5-hydroxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046424 MetaCyc:RXN-1121 Catalysis of the reaction: ferulic acid + NADPH + H+ + O2 = 5-hydroxyferulic acid + H2O + NADP+. GO:0046423 allene-oxide cyclase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046423 EC:5.3.99.6|KEGG_REACTION:R03402|RHEA:22592|MetaCyc:ALLENE-OXIDE-CYCLASE-RXN (9Z)-(13S)-12,13-epoxyoctadeca-9,11,15-trienoate isomerase (cyclizing) Catalysis of the reaction: (9Z,13S,15Z)-12,13-epoxyoctadeca-9,11,15-trienoate = (15Z)-12-oxophyto-10,15-dienoate. GO:0046422 violaxanthin de-epoxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046422 RHEA:32371|EC:1.23.5.1 VDE|violaxanthin:ascorbate oxidoreductase activity Catalysis of the reaction: violaxanthin + 2 ascorbate = zeaxanthin + 2 dehydroascorbate + 2 H2O; and antheraxanthin + ascorbate = zeaxanthin + dehydroascorbate + H2O. GO:0046421 methylisocitrate lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046421 KEGG_REACTION:R00409|RHEA:16809|MetaCyc:METHYLISOCITRATE-LYASE-RXN|EC:4.1.3.30 MICL|(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate pyruvate-lyase (succinate-forming)|2-methylisocitrate lyase activity|(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate pyruvate-lyase activity Catalysis of the reaction: (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate. GO:0046420 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046420 CHEBI:84247 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84247 CHEBI:84246 4-hydroxy-6-heptylpyran-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84246 CL:0002045 Fraction A pre-pro B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002045 pre pro B cell|fraction A A pro-B cell that CD45R/B220-positive, CD43-positive, HSA-low, BP-1-negative and Ly6c-negative. This cell type is also described as being lin-negative, AA4-positive, Kit-positive, IL7Ra-positive and CD45R-positive. CL:0002044 Kit-positive, integrin beta7-high basophil mast progenitor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002044 A basophil mast progenitor cell that is Beta-7 integrin-high, Kit-positive FcRgammaII/III-positive and Sca1-negative. CHEBI:84244 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84244 CL:0002047 Fraction B precursor B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002047 Fr. B|Fraction B A precursor B cell that is CD45RA-positive, CD43-positive, CD24-positive and BP-1-negative. CL:0002049 Fraction C precursor B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002049 Fraction C A precursor B cell is CD45R-positive, CD43-positive, CD24-positive, and BP-positive. Intracellularly expression of surrogate light chain, Rag1 and Rag2, TdT, occurs while there is no expression of mu heavy chain. CHEBI:84241 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84241 GO:0046429 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046429 MetaCyc:RXN0-882|RHEA:26119|EC:1.17.7.1|KEGG_REACTION:R08689 1-hydroxy-2-methyl-2-butenyl 4-diphosphate synthase activity|1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase activity|(E)-4-hydroxy-3-methylbut-2-enyl diphosphate synthase activity|(E)-4-hydroxy-3-methylbut-2-en-1-yl-diphosphate:oxidized ferredoxin oxidoreductase activity Catalysis of the reaction: (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + H2O + 2 oxidized ferredoxin = 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + 2 reduced ferredoxin. CHEBI:84240 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84240 GO:0046428 1,4-dihydroxy-2-naphthoate octaprenyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046428 EC:2.5.1.-|MetaCyc:DMK-RXN|RHEA:30099 1,4-Dihydroxy-2-naphtoate prenyltransferase activity Catalysis of the reaction: 1,4-dihydroxy-2-naphthoate + polyprenylpyrophosphate = dimethylmenaquinone + diphosphate + CO2. GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046427 positive regulation of STAT protein nuclear translocation|up regulation of JAK-STAT cascade|upregulation of JAK-STAT cascade|stimulation of JAK-STAT cascade|activation of JAK-STAT cascade|up-regulation of JAK-STAT cascade|positive regulation of STAT protein import into nucleus Any process that activates or increases the frequency, rate or extent of the JAK-STAT signaling pathway activity. UBERON:0002423 hepatobiliary system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002423 hepaticobiliary system|liver/biliary system|liver and biliary system The part of the digestive system that contains the liver and the biliary system UBERON:0002422 fourth ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002422 4th ventricle|rhombencephalic vesicle|IVth ventricle|hindbrain ventricle|ventriculus quartus|ventricle of hindbrain|fourth ventricle proper|rhombencephalic ventricle|ventricle IV|ventricle of rhombencephalon Part of the ventricular system of the brain, forming a single large irregularly shaped cavity located on the midline of the rhombencephalon, between the medulla, pons and the isthmus ventrally and the cerebellum dorsally. It is continuous with the cerebral aqueduct anteriorally and the central canal of the spinal cord posteriorly. It communicates with the subarachnoid space through its lateral and median apertures. UBERON:0002425 visceral serous pericardium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002425 serous visceral pericardium|epicardium|lamina visceralis pericardii serosi|visceral layer of serous pericardium|visceral lamina of serous pericardium|pericardium visceral mesothelium|visceral pericardium Visceral serous membrane which is continuous with the parietal serous pericardium and is attached to the myocardium[FMA]. UBERON:0002424 oral epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002424 epithelium of mucosa of mouth|epithelium of oral mucosa An epithelium that is part of the mouth and lines the oral cavity, typically stratified squamous, and may be para-, ortho- or non- keratinized. Primary barrier between oral environment and deeper tissues CL:0002041 immature NK T cell stage III biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002041 NKT.44+.NK1.1-.Th A CD24-low, CD44-positive, DX5-low, NK1.1-negative NK T cell. CL:0002040 immature NK T cell stage II biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002040 NKT.44-NK1.1-.Th A CD24-low, CD44-negative, NK1.1-negative NK T cell. UBERON:0002421 hippocampal formation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002421 formatio hippocampi|archipallium|hippocampus|primal cortex|hippocampus (Crosby)|seahorse|major hippocampus Hippocampus (proper) plus dentate gyrus and subiculum[definition derived from NIF comments and ontology alignment]. CL:0002043 CD34-positive, CD38-negative multipotent progenitor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002043 A hematopoietic multipotent progenitor cell that is CD34-positive, CD38-negative, CD45RA-negative, and CD90-negative. CL:0002042 immature NK T cell stage IV biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002042 NKT.44+.NK1.1-.Th A CD24-low, CD44-positive, DX5-high, NK1.1-negative NK T cell. UBERON:0002420 basal ganglion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002420 basal ganglion of telencephalon|basal nucleus|basal ganglia|nuclei basales An individual member of a collection of basal ganglia. Basal ganglia are subcortical masses of gray matter in the forebrain and midbrain that are richly interconnected and so viewed as a functional system. The nuclei usually included are the caudate nucleus (caudoputamen in rodents), putamen, globus pallidus, substantia nigra (pars compacta and pars reticulata) and the subthalamic nucleus. Some also include the nucleus accumbens and ventral pallidum[NIF,modified]. GO:1900507 negative regulation of iron-sulfur-molybdenum cofactor assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900507 inhibition of iron molybdenum cofactor biosynthesis|inhibition of iron molybdenum cofactor biosynthetic process|inhibition of FeMoco assembly|down regulation of FeMoco biosynthetic process|inhibition of iron molybdenum cofactor assembly|down regulation of iron molybdenum cofactor biosynthesis|down-regulation of iron-sulfur-molybdenum cofactor assembly|downregulation of FeMoco biosynthetic process|down regulation of iron molybdenum cofactor biosynthetic process|down regulation of FeMoco assembly|downregulation of iron molybdenum cofactor biosynthetic process|downregulation of iron molybdenum cofactor biosynthesis|downregulation of FeMoco assembly|down regulation of iron molybdenum cofactor assembly|negative regulation of FeMoco biosynthetic process|downregulation of iron-sulfur-molybdenum cofactor assembly|down-regulation of FeMoco biosynthetic process|downregulation of iron molybdenum cofactor assembly|negative regulation of iron molybdenum cofactor biosynthetic process|down-regulation of iron molybdenum cofactor biosynthesis|negative regulation of iron molybdenum cofactor biosynthesis|down-regulation of iron molybdenum cofactor biosynthetic process|down regulation of iron-sulfur-molybdenum cofactor assembly|inhibition of iron-sulfur-molybdenum cofactor assembly|down-regulation of FeMoco assembly|negative regulation of FeMoco assembly|negative regulation of iron molybdenum cofactor assembly|down-regulation of iron molybdenum cofactor assembly|inhibition of FeMoco biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of iron-sulfur-molybdenum cofactor assembly. UBERON:0002409 pericardial fluid biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002409 Transudate contained in the pericardial cavity.[FMA] GO:1900506 regulation of iron-sulfur-molybdenum cofactor assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900506 regulation of FeMoco biosynthetic process|regulation of iron molybdenum cofactor biosynthetic process|regulation of iron molybdenum cofactor biosynthesis|regulation of FeMoco assembly|regulation of iron molybdenum cofactor assembly Any process that modulates the frequency, rate or extent of iron-sulfur-molybdenum cofactor assembly. UBERON:0002408 parietal serous pericardium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002408 lamina parietalis pericardii|parietal layer of serous pericardium|pericardial sac|parietal pericardium|lamina parietalis (pericardii serosum) Parietal serous membrane which is part of the pericardium and forms the outer layer of the pericardial sac. GO:1900509 regulation of pentose catabolic process to ethanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900509 regulation of pentose catabolism to ethanol Any process that modulates the frequency, rate or extent of pentose catabolic process to ethanol. GO:1900508 positive regulation of iron-sulfur-molybdenum cofactor assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900508 up-regulation of iron-sulfur-molybdenum cofactor assembly|upregulation of FeMoco biosynthetic process|activation of iron-sulfur-molybdenum cofactor assembly|up-regulation of iron molybdenum cofactor assembly|upregulation of iron molybdenum cofactor biosynthetic process|upregulation of iron molybdenum cofactor biosynthesis|upregulation of FeMoco assembly|up regulation of FeMoco biosynthetic process|upregulation of iron molybdenum cofactor assembly|positive regulation of FeMoco biosynthetic process|up regulation of iron-sulfur-molybdenum cofactor assembly|up regulation of iron molybdenum cofactor biosynthetic process|up regulation of iron molybdenum cofactor biosynthesis|positive regulation of iron molybdenum cofactor biosynthesis|up regulation of FeMoco assembly|positive regulation of iron molybdenum cofactor biosynthetic process|activation of FeMoco biosynthetic process|positive regulation of FeMoco assembly|up regulation of iron molybdenum cofactor assembly|activation of iron molybdenum cofactor biosynthesis|activation of iron molybdenum cofactor biosynthetic process|positive regulation of iron molybdenum cofactor assembly|up-regulation of FeMoco biosynthetic process|activation of FeMoco assembly|upregulation of iron-sulfur-molybdenum cofactor assembly|up-regulation of iron molybdenum cofactor biosynthetic process|up-regulation of iron molybdenum cofactor biosynthesis|activation of iron molybdenum cofactor assembly|up-regulation of FeMoco assembly Any process that activates or increases the frequency, rate or extent of iron-sulfur-molybdenum cofactor assembly. CHEBI:25883 pentahydroxyflavone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25883 GO:1900503 regulation of cellulosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900503 Any process that modulates the frequency, rate or extent of cellulosome assembly. UBERON:0002405 immune system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002405 Anatomical system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymphoid tissue, lymphocytes including the B cells and T cells, and antibodies. GO:1900502 positive regulation of butyryl-CoA catabolic process to butyrate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900502 up regulation of butyryl-CoA catabolism to butyrate|up-regulation of butyryl-CoA catabolic process to butyrate|upregulation of butyryl-CoA catabolism to butyrate|upregulation of butyryl-CoA catabolic process to butyrate|up-regulation of butyryl-CoA catabolism to butyrate|up regulation of butyryl-CoA catabolic process to butyrate|activation of butyryl-CoA catabolism to butyrate|activation of butyryl-CoA catabolic process to butyrate|positive regulation of butyryl-CoA catabolism to butyrate Any process that activates or increases the frequency, rate or extent of butyryl-CoA catabolic process to butyrate. GO:1900505 positive regulation of cellulosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900505 upregulation of cellulosome assembly|up-regulation of cellulosome assembly|activation of cellulosome assembly|up regulation of cellulosome assembly Any process that activates or increases the frequency, rate or extent of cellulosome assembly. UBERON:0002407 pericardium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002407 The combination of pericardial sac (a double-walled sac containing the heart and the roots of the great vessels) plus fibrous pericardium. GO:1900504 negative regulation of cellulosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900504 down regulation of cellulosome assembly|inhibition of cellulosome assembly|down-regulation of cellulosome assembly|downregulation of cellulosome assembly Any process that stops, prevents or reduces the frequency, rate or extent of cellulosome assembly. UBERON:0002406 pericardial sac biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002406 pericardium a double-walled sac containing the heart and the roots of the great vessels. GO:0046437 D-amino acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046437 D-amino acid biosynthesis|D-amino acid anabolism|D-amino acid synthesis|D-amino acid formation The chemical reactions and pathways resulting in the formation of D-amino acids, the D-enantiomers of amino acids. CHEBI:35209 label biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35209 GO:0046436 D-alanine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046436 D-alanine metabolism The chemical reactions and pathways involving D-alanine, the D-enantiomer of the amino acid alanine, i.e. (2R)-2-aminopropanoic acid. CHEBI:60291 L-alpha-phosphatidylglycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60291 GO:0046435 3-(3-hydroxy)phenylpropionate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046435 3-(3-hydroxy)phenylpropionate metabolism The chemical reactions and pathways involving 3-(3-hydroxy)phenylpropionate, a hydroxylated derivative of phenylpropionate. GO:1900501 negative regulation of butyryl-CoA catabolic process to butyrate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900501 downregulation of butyryl-CoA catabolism to butyrate|inhibition of butyryl-CoA catabolic process to butyrate|down regulation of butyryl-CoA catabolism to butyrate|inhibition of butyryl-CoA catabolism to butyrate|down regulation of butyryl-CoA catabolic process to butyrate|downregulation of butyryl-CoA catabolic process to butyrate|down-regulation of butyryl-CoA catabolism to butyrate|negative regulation of butyryl-CoA catabolism to butyrate|down-regulation of butyryl-CoA catabolic process to butyrate Any process that stops, prevents or reduces the frequency, rate or extent of butyryl-CoA catabolic process to butyrate. GO:0046434 organophosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046434 organophosphate catabolism|organophosphate degradation|organophosphate breakdown The chemical reactions and pathways resulting in the breakdown of organophosphates, any phosphate-containing organic compound. GO:1900500 regulation of butyryl-CoA catabolic process to butyrate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900500 regulation of butyryl-CoA catabolism to butyrate Any process that modulates the frequency, rate or extent of butyryl-CoA catabolic process to butyrate. GO:0046433 2-aminoethylphosphonate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046433 ciliatine metabolic process|2-phosphonoethylamine metabolic process|2-phosphonoethylamine metabolism|ciliatine metabolism|2-aminoethylphosphonate metabolism The chemical reactions and pathways involving 2-aminoethylphosphonate, most abundant and ubiquitous of naturally occurring phosphonates. It is typically found as a conjugate of glycans, lipids, and proteins, which in turn perform essential biochemical functions in specialized lower organisms. CHEBI:84259 iminoarginine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84259 CHEBI:25881 pentahydroxycyclohexanone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25881 GO:0046432 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046432 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA metabolism The chemical reactions and pathways involving 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA, a derivative of coenzyme A. GO:0046431 (R)-4-hydroxymandelate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046431 (R)-4-hydroxymandelate metabolism The chemical reactions and pathways involving (R)-4-hydroxymandelate, the anion of a hydroxylated derivative of mandelate (alpha-hydroxybenzeneacetate). GO:0046430 non-phosphorylated glucose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046430 non-phosphorylated glucose metabolism The chemical reactions and pathways involving non-phosphorylated forms of glucose. CHEBI:84257 3,6-anhydro-L-galactonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84257 CL:0002056 Fraction F mature B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002056 A mature B cell subset originally defined as having being CD45R-positive, IgM-positive, IgD-positive and CD43-negative. Subsequent research demonstrated being CD21-positive and CD23-negative and CD93 negative. PR:000035726 ubiquitin (UBB) biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000035726 UBB/Clv:ubiq A polyubiquitin-B that has been processed by proteolytic cleavage to produce a protein consisting of a Ubiquitin (Pfam:PF00240) domain. There are three copies of ubiquitin in polyubiquitin B. Example: UniProtKB:P0CG47, (1-76) or (77-152) or (153-228). CHEBI:84255 4-hydroxy-5-methyl-6-heptadecylpyran-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84255 CHEBI:35203 molybdopterins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35203 CL:0002058 Gr1-low non-classical monocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002058 A resident monocyte that is Gr-1 low, CD43-positive, and CX3CR1-positive. CHEBI:84253 4-hydroxy-5-methyl-6-pentadecylpyran-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84253 CHEBI:35202 molybdenum coordination entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35202 PR:000035728 ubiquitin biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000035728 ubiquitin A proteolytic cleavage product that gives rise to a protein that corresponds the stand-alone version of the Ubiquitin (Pfam:PF00240) domain. CL:0002059 CD8alpha-positive thymic conventional dendritic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002059 CD8alpha-alpha-positive thymic conventional dendritic cell|DC.8+.Th A conventional thymic dendritic cell that is CD8alpha-positive. CHEBI:84251 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84251 PR:000035722 ubiquitin (UBA52) biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000035722 UBA52/Clv:ubiq A ubiquitin-60S ribosomal protein L40 that has been processed by proteolytic cleavage. This form is the N-terminal region consisting of the Ubiquitin (Pfam:PF00240) domain. Example: UniProtKB:P62987, 1-76. CHEBI:35204 tracer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35204 GO:0046439 L-cysteine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046439 L-cysteine metabolism The chemical reactions and pathways involving L-cysteine, the L-enantiomer of 2-amino-3-mercaptopropanoic acid, i.e. (2R)-2-amino-3-mercaptopropanoic acid. GO:0046438 D-cysteine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046438 D-cysteine metabolism The chemical reactions and pathways involving D-cysteine, (S)-2-amino-3-mercaptopropanoic acid, which occurs naturally in firefly luciferin. UBERON:0002412 vertebra biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002412 vertebrae|vertebra bone The ossified form of a vertebral element, a skeletal element that forms around the notochord and is part of the vertebral column. UBERON:0002411 clitoris biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002411 the small, erectile body located at the anterior end of the vulva CL:0002050 Fraction C' precursor B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002050 Fraction C-prime|Fr. C' A pre-BCR-positive precursor B cell that is CD24-high, CD25-positive, CD43-positive, CD45R-positive and BP-positive. PR:000035720 ubiquitin (UBC) biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000035720 UBC/Clv:ubiq A polyubiquitin-C that has been processed by proteolytic cleavage to produce a protein consisting of a Ubiquitin (Pfam:PF00240) domain. There are nine copies of ubiquitin in polyubiquitin C. Example: UniProtKB:P0CG48, (1-76) or (77-152) or (153-228) or (229-304) or (305-380) or (381-456) or (457-532) or (533-608) or (609-684). UBERON:0002413 cervical vertebra biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002413 vertebrae cervicales|cervical vertebrae A vertebra that is located in the cervical region of the vertebral column. CL:0002052 Fraction D precursor B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002052 Fr. D|Fraction D pre-B cell A pre-B cell that is pre-BCR-negative, and the kappa- and lambda- light immunoglobulin light chain-negative, CD43-low, and is BP-1-positive, CD45R-positive and CD25-positive. This cell type is also described as being AA4-positive, IgM-negative, CD19-positive, CD43-low/negative, and HSA-positive. UBERON:0002410 autonomic nervous system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002410 peripheral autonomic nervous system|divisio autonomica systematis nervosi peripherici|visceral nervous system|autonomic division of peripheral nervous system|ANS|autonomic part of peripheral nervous system|pars autonomica systematis nervosi peripherici|divisio autonomica systematis nervosi peripherici The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands[GO]. CL:0002054 Fraction E immature B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002054 An immature B cell that is IgM-positive, CD45R-positive, CD43-low, CD25-negative, and CD127-negative. This cell type has also been described as being AA4-positive, IgM-positive, CD19-positive, CD43-low/negative, and HSA-positive. CHEBI:59296 alpha-L-Fucp-(1->2)-beta-D-Galp-(1->3)-beta-D-GlcpNAc biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59296 CHEBI:59295 beta-D-Galp-(1->3)-[alpha-L-Fucp-(1->4)]-beta-D-GlcpNAc biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59295 CHEBI:59294 alpha-L-Fucp-(1->3)-[beta-D-Galp-(1->4)]-beta-D-GlcpNAc biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59294 CHEBI:132988 bradykinin(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132988 CHEBI:132987 alliin zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132987 CHEBI:132989 O-acetylhomoserine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132989 CHEBI:74819 2-methyl-L-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74819 CHEBI:74818 heteroaryl hydroxy compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74818 CHEBI:132992 radiosensitizing agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132992 CHEBI:132966 hippurate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132966 CHEBI:59270 2-hydroxymyristic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59270 CHEBI:59266 amino trisaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59266 CHEBI:132960 3-phosphoglycerate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132960 CHEBI:35291 all-trans-retinoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35291 CHEBI:35294 carbopolycyclic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35294 CHEBI:35293 fused compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35293 CHEBI:35296 ortho-fused polycyclic arene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35296 CHEBI:35295 homopolycyclic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35295 CHEBI:35297 acene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35297 CHEBI:59268 amino pentasaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59268 CHEBI:74831 1-linolenoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74831 CHEBI:74830 1-linoleoyl-2-oleoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74830 CHEBI:74833 1-linolenoyl-2-oleoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74833 CHEBI:74836 1-oleoyl-2-palmitoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74836 CHEBI:74839 1-oleoyl-2-stearoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74839 CHEBI:132977 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132977 CHEBI:132978 12alpha-hydroxy-3-oxochola-4,6-dien-24-oyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132978 CHEBI:132970 5-ammoniolevulinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132970 CHEBI:59252 linear tetrapyrrole anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59252 CHEBI:59258 N-hydroxy-alpha-amino-acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59258 CHEBI:74841 1-heptadecanoyl-2-oleoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74841 GO:0022411 cellular component disassembly biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0022411 cellular component disassembly at cellular level|cell structure disassembly A cellular process that results in the breakdown of a cellular component. GO:0022410 circadian sleep/wake cycle process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022410 A behavioral process involved in the cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm. CHEBI:74845 1-oleoyl-2-heptadecanoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74845 GO:0022413 reproductive process in single-celled organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022413 A process, occurring at the cellular level, that is involved in the reproductive function of a single-celled organism. GO:0022412 cellular process involved in reproduction in multicellular organism biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022412 reproductive cellular process in multicellular organism A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism. CHEBI:74847 1-stearoyl-2-oleoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74847 CHEBI:132944 octadec-9-enoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132944 CHEBI:74849 1-oleoyl-2-linoleoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74849 CHEBI:132943 aspartate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132943 CHEBI:132946 (R)-2-hydroxyglutaryl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132946 CHEBI:132948 pyridoxate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132948 CHEBI:60203 D-glycero-alpha-D-manno-heptose 7-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60203 CHEBI:60202 D-glycero-beta-D-manno-heptose 7-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60202 CHEBI:132940 1,3,7-trimethylurate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132940 CHEBI:60205 D-glycero-alpha-D-manno-heptose 1,7-bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60205 CHEBI:59240 phthiocerol A biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59240 CHEBI:60204 D-glycero-beta-D-manno-heptose 7-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60204 CHEBI:132942 quinolinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132942 CHEBI:60207 D-glycero-alpha-D-manno-heptose 1,7-bisphosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60207 CHEBI:132941 2-hydroxyglutarate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132941 CHEBI:60206 D-glycero-beta-D-manno-heptose 1,7-bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60206 GO:0022415 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0022415 GO:0022414 reproductive process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022414 single organism reproductive process A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents. CHEBI:60208 D-glycero-beta-D-manno-heptose 1,7-bisphosphate(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60208 GO:0022417 protein maturation by protein folding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022417 The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that results in the attainment of the full functional capacity of a protein. CHEBI:35272 O-glycosyl amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35272 GO:0022416 chaeta development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022416 bristle development The process whose specific outcome is the progression of a chaeta over time, from its formation to the mature structure. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell. CHEBI:35274 ammonium ion derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35274 CHEBI:35276 ammonium compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35276 CHEBI:74840 1-heptadecanoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74840 CHEBI:35275 S-glycosyl compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35275 CHEBI:74853 2,3-bis-O-phytanyl-sn-glycero-3-phospho-L-serine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74853 CHEBI:74852 1-oleoyl-2-pentadecanoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74852 GO:0022400 regulation of rhodopsin mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022400 regulation of rhodopsin mediated signalling Any process that modulates the frequency, rate or extent of rhodopsin-mediated signaling. GO:0022402 cell cycle process biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0022402 The cellular process that ensures successive accurate and complete genome replication and chromosome segregation. CHEBI:35290 1,2-dichlorobenzene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35290 GO:0022401 negative adaptation of signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022401 negative adaptation of signal transduction pathway|negative adaptation of signalling pathway The negative regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus. CHEBI:132955 azelaate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132955 CHEBI:132954 sebacate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132954 CHEBI:132957 N-acetylmethioninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_132957 CHEBI:132958 N-acetylmethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132958 CHEBI:35288 all-trans-violaxanthin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35288 CHEBI:132951 maleate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132951 CHEBI:132950 tartrate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132950 CHEBI:60215 W-molybdopterin cofactor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60215 CHEBI:132953 suberate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132953 CHEBI:132952 oxalate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_132952 GO:0022404 molting cycle process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022404 A multicellular organismal process involved in the periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin. CHEBI:35281 onium betaine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35281 GO:0022403 cell cycle phase biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0022403 One of the distinct periods or stages into which the cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events. CHEBI:35280 L-proline betaine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35280 GO:0022406 membrane docking biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0022406 membrane docking The initial attachment of a membrane or protein to a target membrane. Docking requires only that the proteins come close enough to interact and adhere. CHEBI:35282 sulfonium betaine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35282 GO:0022405 hair cycle process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022405 A multicellular organismal process involved in the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body. GO:0022408 negative regulation of cell-cell adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022408 down-regulation of cell-cell adhesion|downregulation of cell-cell adhesion|down regulation of cell-cell adhesion|inhibition of cell-cell adhesion Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell. CHEBI:59238 cyclic fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59238 CHEBI:35285 iminium betaine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35285 CHEBI:35284 ammonium betaine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35284 GO:0022407 regulation of cell-cell adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022407 Any process that modulates the frequency, rate or extent of attachment of a cell to another cell. CHEBI:59237 phenolic phthiocerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59237 CHEBI:35287 acylcholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35287 CHEBI:74851 5-(2-methoxy-2-oxoethyl)uridine 5'-monophosphate residue(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74851 GO:0022409 positive regulation of cell-cell adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022409 activation of cell-cell adhesion|up regulation of cell-cell adhesion|upregulation of cell-cell adhesion|stimulation of cell-cell adhesion|up-regulation of cell-cell adhesion Any process that activates or increases the rate or extent of cell adhesion to another cell. CHEBI:74850 1-stearoyl-sn-glycero-3-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74850 CHEBI:35286 iminium ion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35286 GO:0071363 cellular response to growth factor stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071363 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus. GO:0071362 cellular response to ether biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071362 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ether stimulus. GO:0071361 cellular response to ethanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071361 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus. GO:0071360 cellular response to exogenous dsRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071360 cellular response to viral dsRNA|cellular response to exogenous double-stranded RNA Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus. GO:1900477 negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900477 Any process that stops, prevents, or reduces the frequency, rate or extent of G1/S transition of mitotic cell cycle by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:1900476 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1900476 GO:1900479 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1900479 GO:1900478 obsolete positive regulation of sulfate assimilation by positive regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900478 up-regulation of sulfate assimilation by positive regulation of transcription from RNA polymerase II promoter|up regulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter|activation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter|activation of sulfate assimilation by positive regulation of transcription from RNA polymerase II promoter|upregulation of sulphate assimilation by positive regulation of transcription from RNA polymerase II promoter|up-regulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter|upregulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter|up regulation of sulfate assimilation by positive regulation of transcription from RNA polymerase II promoter|up regulation of sulphate assimilation by positive regulation of transcription from RNA polymerase II promoter|upregulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter|up-regulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter|positive regulation of sulphate assimilation by positive regulation of transcription from RNA polymerase II promoter|upregulation of sulfate assimilation by positive regulation of transcription from RNA polymerase II promoter|activation of sulphate assimilation by positive regulation of transcription from RNA polymerase II promoter|activation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter|up regulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter|positive regulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter|up-regulation of sulphate assimilation by positive regulation of transcription from RNA polymerase II promoter|positive regulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that activates or increases the frequency, rate or extent of sulfate assimilation by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:1900473 obsolete negative regulation of phosphatidylcholine biosynthetic process by negative regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900473 negative regulation of phosphatidylcholine anabolism by negative regulation of transcription from RNA polymerase II promoter|negative regulation of phosphatidylcholine biosynthesis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of phosphatidylcholine synthesis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of phosphatidylcholine formation by negative regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of phosphatidylcholine biosynthetic process by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:1900472 obsolete positive regulation of phosphatidylcholine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900472 positive regulation of phosphatidylcholine anabolism by positive regulation of transcription from RNA polymerase II promoter|positive regulation of phosphatidylcholine synthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of phosphatidylcholine formation by positive regulation of transcription from RNA polymerase II promoter|positive regulation of phosphatidylcholine biosynthesis by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that activates or increases the frequency, rate or extent of phosphatidylcholine biosynthetic process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:1900475 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1900475 GO:1900474 obsolete negative regulation of mating type switching by negative regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900474 OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of mating type switching by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:1900480 regulation of diacylglycerol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900480 regulation of diacylglycerol biosynthesis|regulation of diacylglycerol anabolism|regulation of diacylglycerol synthesis|regulation of diacylglycerol formation Any process that modulates the frequency, rate or extent of diacylglycerol biosynthetic process. GO:1900482 positive regulation of diacylglycerol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900482 upregulation of diacylglycerol biosynthetic process|upregulation of diacylglycerol biosynthesis|activation of diacylglycerol anabolism|up-regulation of diacylglycerol formation|activation of diacylglycerol synthesis|positive regulation of diacylglycerol anabolism|up regulation of diacylglycerol anabolism|activation of diacylglycerol formation|up regulation of diacylglycerol biosynthetic process|positive regulation of diacylglycerol synthesis|up regulation of diacylglycerol biosynthesis|positive regulation of diacylglycerol biosynthesis|activation of diacylglycerol biosynthetic process|up regulation of diacylglycerol synthesis|positive regulation of diacylglycerol formation|up regulation of diacylglycerol formation|activation of diacylglycerol biosynthesis|upregulation of diacylglycerol anabolism|upregulation of diacylglycerol synthesis|up-regulation of diacylglycerol biosynthetic process|up-regulation of diacylglycerol biosynthesis|upregulation of diacylglycerol formation|up-regulation of diacylglycerol anabolism|up-regulation of diacylglycerol synthesis Any process that activates or increases the frequency, rate or extent of diacylglycerol biosynthetic process. GO:1900481 negative regulation of diacylglycerol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900481 negative regulation of diacylglycerol anabolism|down-regulation of diacylglycerol anabolism|down regulation of diacylglycerol biosynthesis|down regulation of diacylglycerol biosynthetic process|negative regulation of diacylglycerol synthesis|down-regulation of diacylglycerol synthesis|downregulation of diacylglycerol biosynthetic process|downregulation of diacylglycerol biosynthesis|negative regulation of diacylglycerol formation|down-regulation of diacylglycerol formation|downregulation of diacylglycerol anabolism|downregulation of diacylglycerol synthesis|down regulation of diacylglycerol anabolism|down-regulation of diacylglycerol biosynthetic process|down-regulation of diacylglycerol biosynthesis|negative regulation of diacylglycerol biosynthesis|downregulation of diacylglycerol formation|down regulation of diacylglycerol synthesis|inhibition of diacylglycerol anabolism|down regulation of diacylglycerol formation|inhibition of diacylglycerol biosynthetic process|inhibition of diacylglycerol synthesis|inhibition of diacylglycerol biosynthesis|inhibition of diacylglycerol formation Any process that stops, prevents or reduces the frequency, rate or extent of diacylglycerol biosynthetic process. GO:0071369 cellular response to ethylene stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071369 cellular response to ethene stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus. GO:0071368 cellular response to cytokinin stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071368 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokinin stimulus. GO:0071367 cellular response to brassinosteroid stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071367 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brassinosteroid stimulus. GO:0071366 cellular response to indolebutyric acid stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071366 cellular response to indole-3-butyric acid stimulus|cellular response to IBA stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indolebutyric acid stimulus. GO:0071365 cellular response to auxin stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071365 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus. GO:0071364 cellular response to epidermal growth factor stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071364 cellular response to EGF stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus. GO:0071352 cellular response to interleukin-2 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071352 cellular response to IL-2 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-2 stimulus. GO:0071351 cellular response to interleukin-18 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071351 cellular response to IL-18 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-18 stimulus. GO:0071350 cellular response to interleukin-15 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071350 cellular response to IL-15 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-15 stimulus. GO:1900488 negative regulation of [2Fe-2S] cluster assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900488 inhibition of 2Fe-2S cluster assembly|down-regulation of [2Fe-2S] cluster biosynthetic process|negative regulation of [2Fe-2S] cluster biosynthetic process|down-regulation of [2Fe-2S] cluster assembly|inhibition of [2Fe-2S] cluster assembly|inhibition of [2Fe-2S] cluster biosynthetic process|down regulation of 2Fe-2S cluster assembly|downregulation of 2Fe-2S cluster assembly|down regulation of [2Fe-2S] cluster biosynthetic process|down regulation of [2Fe-2S] cluster assembly|downregulation of [2Fe-2S] cluster biosynthetic process|downregulation of [2Fe-2S] cluster assembly|down-regulation of 2Fe-2S cluster assembly|negative regulation of 2Fe-2S cluster assembly Any process that stops, prevents or reduces the frequency, rate or extent of [2Fe-2S] cluster assembly. GO:1900487 regulation of [2Fe-2S] cluster assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900487 regulation of 2Fe-2S cluster assembly|regulation of [2Fe-2S] cluster biosynthetic process Any process that modulates the frequency, rate or extent of [2Fe-2S] cluster assembly. GO:1900489 positive regulation of [2Fe-2S] cluster assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900489 positive regulation of [2Fe-2S] cluster biosynthetic process|activation of [2Fe-2S] cluster assembly|up-regulation of 2Fe-2S cluster assembly|activation of [2Fe-2S] cluster biosynthetic process|up-regulation of [2Fe-2S] cluster biosynthetic process|up-regulation of [2Fe-2S] cluster assembly|upregulation of 2Fe-2S cluster assembly|upregulation of [2Fe-2S] cluster biosynthetic process|upregulation of [2Fe-2S] cluster assembly|up regulation of 2Fe-2S cluster assembly|positive regulation of 2Fe-2S cluster assembly|activation of 2Fe-2S cluster assembly|up regulation of [2Fe-2S] cluster biosynthetic process|up regulation of [2Fe-2S] cluster assembly Any process that activates or increases the frequency, rate or extent of [2Fe-2S] cluster assembly. GO:1900484 negative regulation of protein targeting to vacuolar membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900484 downregulation of protein targeting to vacuolar membrane|down regulation of protein targeting to vacuolar membrane|inhibition of protein targeting to vacuolar membrane|down-regulation of protein targeting to vacuolar membrane Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to vacuolar membrane. GO:1900483 regulation of protein targeting to vacuolar membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900483 Any process that modulates the frequency, rate or extent of protein targeting to vacuolar membrane. GO:1900486 positive regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900486 upregulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway|up-regulation of isopentenyl diphosphate synthesis, mevalonate pathway|up-regulation of isopentenyl diphosphate formation, mevalonate pathway|upregulation of isopentenyl diphosphate anabolism, mevalonate pathway|upregulation of Ac-MVA pathway|up-regulation of acetate-mevalonate pathway|up-regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway|upregulation of isopentenyl diphosphate synthesis, mevalonate pathway|activation of isopentenyl diphosphate biosynthetic process, mevalonate pathway|upregulation of isopentenyl diphosphate formation, mevalonate pathway|activation of acetate-mevalonate pathway|up regulation of isopentenyl diphosphate anabolism, mevalonate pathway|up-regulation of Ac-MVA pathway|positive regulation of isopentenyl diphosphate anabolism, mevalonate pathway|positive regulation of acetate-mevalonate pathway|up regulation of isopentenyl diphosphate synthesis, mevalonate pathway|up regulation of acetate-mevalonate pathway|positive regulation of isopentenyl diphosphate synthesis, mevalonate pathway|up regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway|up regulation of isopentenyl diphosphate formation, mevalonate pathway|activation of isopentenyl diphosphate anabolism, mevalonate pathway|activation of Ac-MVA pathway|positive regulation of isopentenyl diphosphate formation, mevalonate pathway|activation of isopentenyl diphosphate synthesis, mevalonate pathway|positive regulation of Ac-MVA pathway|up-regulation of isopentenyl diphosphate anabolism, mevalonate pathway|up regulation of Ac-MVA pathway|activation of isopentenyl diphosphate formation, mevalonate pathway|upregulation of acetate-mevalonate pathway Any process that activates or increases the frequency, rate or extent of isopentenyl diphosphate biosynthetic process, mevalonate pathway. GO:1900485 positive regulation of protein targeting to vacuolar membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900485 up regulation of protein targeting to vacuolar membrane|upregulation of protein targeting to vacuolar membrane|activation of protein targeting to vacuolar membrane|up-regulation of protein targeting to vacuolar membrane Any process that activates or increases the frequency, rate or extent of protein targeting to vacuolar membrane. GO:1900491 regulation of [4Fe-4S] cluster assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900491 regulation of [4Fe-4S] cluster biosynthetic process|regulation of 4Fe-4S cluster assembly Any process that modulates the frequency, rate or extent of [4Fe-4S] cluster assembly. GO:1900490 positive regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900490 upregulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity|positive regulation of HMG-CoA reductase activity|up regulation of HMG-CoA reductase activity|upregulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity|up-regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity|activation of hydroxymethylglutaryl-CoA reductase (NADPH) activity|upregulation of HMG-CoA reductase activity|up-regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity|activation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity|up regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity|up-regulation of HMG-CoA reductase activity|positive regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity|activation of HMG-CoA reductase activity|up regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity Any process that activates or increases the frequency, rate or extent of hydroxymethylglutaryl-CoA reductase (NADPH) activity. GO:1900493 positive regulation of [4Fe-4S] cluster assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900493 activation of 4Fe-4S cluster assembly|positive regulation of 4Fe-4S cluster assembly|upregulation of [4Fe-4S] cluster biosynthetic process|upregulation of [4Fe-4S] cluster assembly|up-regulation of 4Fe-4S cluster assembly|up regulation of [4Fe-4S] cluster biosynthetic process|up regulation of [4Fe-4S] cluster assembly|activation of [4Fe-4S] cluster assembly|positive regulation of [4Fe-4S] cluster biosynthetic process|activation of [4Fe-4S] cluster biosynthetic process|upregulation of 4Fe-4S cluster assembly|up-regulation of [4Fe-4S] cluster biosynthetic process|up-regulation of [4Fe-4S] cluster assembly|up regulation of 4Fe-4S cluster assembly Any process that activates or increases the frequency, rate or extent of [4Fe-4S] cluster assembly. GO:1900492 negative regulation of [4Fe-4S] cluster assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900492 down-regulation of 4Fe-4S cluster assembly|negative regulation of 4Fe-4S cluster assembly|down regulation of [4Fe-4S] cluster biosynthetic process|down regulation of [4Fe-4S] cluster assembly|downregulation of [4Fe-4S] cluster biosynthetic process|inhibition of 4Fe-4S cluster assembly|downregulation of [4Fe-4S] cluster assembly|down-regulation of [4Fe-4S] cluster biosynthetic process|negative regulation of [4Fe-4S] cluster biosynthetic process|down-regulation of [4Fe-4S] cluster assembly|down regulation of 4Fe-4S cluster assembly|inhibition of [4Fe-4S] cluster assembly|downregulation of 4Fe-4S cluster assembly|inhibition of [4Fe-4S] cluster biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of [4Fe-4S] cluster assembly. GO:0071359 cellular response to dsRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071359 cellular response to double-stranded RNA Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded RNA stimulus. GO:0071358 cellular response to type III interferon biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071358 cellular response to type III IFN|cellular response to interferon-lambda Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type III interferon stimulus. Interferon lambda is the only member of the type III interferon found so far. GO:0071357 cellular response to type I interferon biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071357 cellular response to type I IFN Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type I interferon stimulus. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. GO:0071356 cellular response to tumor necrosis factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071356 cellular response to TNF Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus. GO:0071355 cellular response to interleukin-9 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071355 cellular response to IL-9 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-9 stimulus. GO:0071354 cellular response to interleukin-6 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071354 cellular response to IL-6 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus. GO:0071353 cellular response to interleukin-4 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071353 cellular response to IL-4 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-4 stimulus. GO:0071385 cellular response to glucocorticoid stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071385 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects. GO:0071384 cellular response to corticosteroid stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071384 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids. GO:0071383 cellular response to steroid hormone stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071383 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus. GO:0071382 cellular response to prostaglandin I stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071382 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin I stimulus. GO:0071381 cellular response to prostaglandin F stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071381 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin F stimulus. GO:0071380 cellular response to prostaglandin E stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071380 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus. GO:1900499 positive regulation of butyryl-CoA catabolic process to butanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900499 activation of butyryl-CoA catabolic process to butanol|up-regulation of butyryl-CoA catabolic process to butanol|up regulation of butyryl-CoA catabolism to butanol|positive regulation of butyryl-CoA catabolism to butanol|activation of butyryl-CoA catabolism to butanol|up regulation of butyryl-CoA catabolic process to butanol|up-regulation of butyryl-CoA catabolism to butanol|upregulation of butyryl-CoA catabolic process to butanol|upregulation of butyryl-CoA catabolism to butanol Any process that activates or increases the frequency, rate or extent of butyryl-CoA catabolic process to butanol. GO:1900498 negative regulation of butyryl-CoA catabolic process to butanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900498 down regulation of butyryl-CoA catabolism to butanol|downregulation of butyryl-CoA catabolism to butanol|down-regulation of butyryl-CoA catabolic process to butanol|negative regulation of butyryl-CoA catabolism to butanol|down-regulation of butyryl-CoA catabolism to butanol|downregulation of butyryl-CoA catabolic process to butanol|down regulation of butyryl-CoA catabolic process to butanol|inhibition of butyryl-CoA catabolic process to butanol|inhibition of butyryl-CoA catabolism to butanol Any process that stops, prevents or reduces the frequency, rate or extent of butyryl-CoA catabolic process to butanol. GO:1900495 negative regulation of butyryl-CoA biosynthetic process from acetyl-CoA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900495 down-regulation of butyryl-CoA biosynthesis from acetyl-CoA|down-regulation of butyryl-CoA biosynthetic process from acetyl-CoA|negative regulation of butyryl-CoA biosynthesis from acetyl-CoA|downregulation of butyryl-CoA biosynthetic process from acetyl-CoA|downregulation of butyryl-CoA biosynthesis from acetyl-CoA|down regulation of butyryl-CoA biosynthetic process from acetyl-CoA|down regulation of butyryl-CoA biosynthesis from acetyl-CoA|inhibition of butyryl-CoA biosynthetic process from acetyl-CoA|inhibition of butyryl-CoA biosynthesis from acetyl-CoA Any process that stops, prevents or reduces the frequency, rate or extent of butyryl-CoA biosynthetic process from acetyl-CoA. GO:1900494 regulation of butyryl-CoA biosynthetic process from acetyl-CoA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900494 regulation of butyryl-CoA biosynthesis from acetyl-CoA Any process that modulates the frequency, rate or extent of butyryl-CoA biosynthetic process from acetyl-CoA. GO:1900497 regulation of butyryl-CoA catabolic process to butanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900497 regulation of butyryl-CoA catabolism to butanol Any process that modulates the frequency, rate or extent of butyryl-CoA catabolic process to butanol. CHEBI:142396 trans-feruloylacetyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_142396 GO:1900496 positive regulation of butyryl-CoA biosynthetic process from acetyl-CoA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900496 activation of butyryl-CoA biosynthesis from acetyl-CoA|positive regulation of butyryl-CoA biosynthesis from acetyl-CoA|up regulation of butyryl-CoA biosynthesis from acetyl-CoA|up regulation of butyryl-CoA biosynthetic process from acetyl-CoA|upregulation of butyryl-CoA biosynthetic process from acetyl-CoA|upregulation of butyryl-CoA biosynthesis from acetyl-CoA|up-regulation of butyryl-CoA biosynthetic process from acetyl-CoA|up-regulation of butyryl-CoA biosynthesis from acetyl-CoA|activation of butyryl-CoA biosynthetic process from acetyl-CoA Any process that activates or increases the frequency, rate or extent of butyryl-CoA biosynthetic process from acetyl-CoA. GO:0071389 cellular response to mineralocorticoid stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071389 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance. GO:0071388 cellular response to cortisone stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071388 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisone stimulus. Cortisone is a natural glucocorticoid steroid hormone that is metabolically convertible to cortisol. Cortisone is synthesized from cholesterol in the cortex of the adrenal gland under the stimulation of adrenocorticotropin hormone (ACTH). The main physiological effect of cortisone is on carbohydrate metabolism; it can stimulate increased glucose release from the liver, increased liver glycogen synthesis, and decreased utilization of glucose by the tissues. GO:0071387 cellular response to cortisol stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071387 cellular response to hydrocortisone stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisol stimulus. Cortisol is the major natural glucocorticoid synthesized in the zona fasciculata of the adrenal cortex; it affects the metabolism of glucose, protein, and fats and has appreciable mineralocorticoid activity. It also regulates the immune system and affects many other functions. GO:0071386 cellular response to corticosterone stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071386 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosterone stimulus. Corticosterone is a 21 carbon steroid hormone of the corticosteroid type, produced in the cortex of the adrenal glands. In many species, corticosterone is the principal glucocorticoid, involved in regulation of fuel metabolism, immune reactions, and stress responses. GO:0071374 cellular response to parathyroid hormone stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071374 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a parathyroid hormone stimulus. GO:0071373 cellular response to luteinizing hormone stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071373 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a luteinizing hormone stimulus. GO:0071372 cellular response to follicle-stimulating hormone stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071372 cellular response to follicle stimulating hormone stimulus|cellular response to FSH stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus. GO:0071371 cellular response to gonadotropin stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071371 cellular response to gonadotrophin stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus. GO:0071370 cellular response to gibberellin stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071370 cellular response to gibberellic acid stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gibberellin stimulus. CHEBI:142389 trans-feruloylacetyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142389 CHEBI:142384 fatty acid 14:2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_142384 GO:0071379 cellular response to prostaglandin stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071379 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin stimulus. GO:0071378 cellular response to growth hormone stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071378 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth. GO:0071377 cellular response to glucagon stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071377 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus. GO:0071376 cellular response to corticotropin-releasing hormone stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071376 cellular response to corticotropin-releasing factor stimulus|cellular response to corticoliberin stimulus|cellular response to CRF stimulus|cellular response to CRH stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticotropin-releasing hormone stimulus. Corticotropin-releasing hormone is a peptide hormone involved in the stress response. GO:0071375 cellular response to peptide hormone stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071375 cellular response to polypeptide hormone stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals. CHEBI:142378 ditrans,polycis-dodecaprenyl phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_142378 GO:0071396 cellular response to lipid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071396 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus. CHEBI:142361 purines 2'-deoxy-D-ribonucleoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142361 GO:0071395 cellular response to jasmonic acid stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071395 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus. GO:0071394 cellular response to testosterone stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071394 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus. GO:0071393 cellular response to progesterone stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071393 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus. GO:0071392 cellular response to estradiol stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071392 cellular response to E2 stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen. GO:0071391 cellular response to estrogen stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071391 cellular response to oestrogen stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics. GO:0071390 cellular response to ecdysone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071390 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ecdysone stimulus. GO:0071399 cellular response to linoleic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071399 cellular response to linoleate Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a linoleic acid stimulus. GO:0071398 cellular response to fatty acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071398 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus. GO:0071397 cellular response to cholesterol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071397 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus. CHEBI:142355 purines D-ribonucleoside biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142355 CHEBI:142345 ditrans,polycis-dodecaprenyl phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142345 CHEBI:59198 dichlorochromopyrrolate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59198 CHEBI:59197 pyrroledicarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59197 CHEBI:59196 dichlorochromopyrrolic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59196 CHEBI:59195 7-chloro-alpha,beta-didehydrotryptophan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59195 CHEBI:142348 hexahydronaphthalenes biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_142348 CHEBI:59194 2-iminio-3-(7-chloroindol-3-yl)propionate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59194 GO:0046327 glycerol biosynthetic process from pyruvate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046327 glycerol synthesis from pyruvate|glycerol formation from pyruvate|glyceroneogenesis|glycerol anabolism from pyruvate The chemical reactions and pathways resulting in the formation of glycerol, 1,2,3-propanetriol, from other compounds, including pyruvate. GO:0046326 positive regulation of glucose import biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046326 upregulation of glucose import|stimulation of glucose import|up-regulation of glucose import|activation of glucose import|positive regulation of glucose uptake|up regulation of glucose import Any process that activates or increases the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle. GO:0046325 negative regulation of glucose import biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046325 downregulation of glucose import|down regulation of glucose import|inhibition of glucose import|negative regulation of glucose uptake|down-regulation of glucose import Any process that stops, prevents, or reduces the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle. GO:0046324 regulation of glucose import biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046324 regulation of glucose uptake Any process that modulates the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle. GO:0046323 glucose import biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046323 Wikipedia:Glucose_uptake glucose uptake The directed movement of the hexose monosaccharide glucose into a cell or organelle. CHEBI:60186 EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60186 GO:0046322 negative regulation of fatty acid oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046322 downregulation of fatty acid oxidation|down regulation of fatty acid oxidation|inhibition of fatty acid oxidation|down-regulation of fatty acid oxidation Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid oxidation. CHEBI:84149 4-hydroxy-6-undecylpyran-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84149 GO:0046321 positive regulation of fatty acid oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046321 up regulation of fatty acid oxidation|upregulation of fatty acid oxidation|stimulation of fatty acid oxidation|up-regulation of fatty acid oxidation|activation of fatty acid oxidation Any process that activates or increases the frequency, rate or extent of fatty acid oxidation. CHEBI:60187 alpha-D-Gal-(1->3)-beta-D-Gal-(1->4)-D-Gal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60187 GO:0046320 regulation of fatty acid oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046320 Any process that modulates the frequency, rate or extent of fatty acid oxidation. UBERON:0002481 bone tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002481 portion of bone tissue|mineralized bone tissue|bone|calcium tissue|osteogenic tissue|osseous tissue Skeletal tissue with a collagen-rich extracellular matrix vascularized, mineralized with hydroxyapatite and typically including osteocytes located in lacunae that communicate with one another by cell processes (in canaliculi). Bone is deposited by osteoblasts. GO:0061960 regulation of heme oxygenase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061960 Any process that modulates the frequency, or rate of heme oxygenase activity. CHEBI:84146 3beta-hydroxycholest-5-en-26-oate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84146 CHEBI:60189 4-(4-deoxy-alpha-D-gluc-4-enosyluronic acid)-D-galacturonate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60189 CHEBI:84145 3beta-hydroxycholest-5-en-26-al biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84145 UBERON:0002483 trabecular bone tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002483 cancellous bone|trabecular bone|substantia spongiosa|substantia trabecularis ossium|cancellous bone tissue|cancellated bone|spongy bone|substantia spongiosa ossium|substantia trabecularis|trabecular substance|spongy bone tissue bone tissue that has a lattice-like or spongy structure; it is highly vascular and contains intercommunicating spaces filled with bone marrow GO:0061962 negative regulation of heme oxygenase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061962 Any process that stops, prevents, or reduces the frequency or rate of heme oxygenase activity. CHEBI:84144 L-phenylalanine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84144 UBERON:0002482 lamellar bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002482 Bone tissue that has a regular parallel alignment of collagen into sheets (lamellae) and is mechanically strong. CL:0002145 ciliated columnar cell of tracheobronchial tree biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002145 A ciliated columnar cell found in the trachea and bronchus. Vary from low to tall columnar; possesses up to 300 cilia at its surface, interspersed with long irregular microvilli with the cilia varying in length from about 6um in the trachea to about 4um in the terminal bronchioles; driving force of the ciliary current in the bronchial tree. GO:0061961 positive regulation of heme oxygenase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061961 Any process that activates or increases the frequency or rate of heme oxygenase activity. CHEBI:84143 D-phenylalanine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84143 GO:0061964 negative regulation of entry into reproductive diapause biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061964 Any process that stops, prevents, or reduces the frequency, rate or extent of the dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli. CHEBI:84142 1D-myo-inositol 2-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84142 GO:0061963 regulation of entry into reproductive diapause biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061963 Any process that modulates the rate or extent of the dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli. CHEBI:84141 1D-myo-inositol 5-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84141 GO:0046329 negative regulation of JNK cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046329 down regulation of JNK cascade|downregulation of JNK cascade|down-regulation of JNK cascade|inhibition of JNK cascade Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the JNK cascade. GO:0061966 establishment of left/right asymmetry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061966 The initial formation of the type asymmetry in an organism's body plan or part of an organism with respect to the left and right halves. CHEBI:84140 myo-inositol monophosphate derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84140 GO:0061965 positive regulation of entry into reproductive diapause biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061965 Any process that activates or increases the rate or extent of the dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli. CL:0002149 epithelial cell of uterus biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002149 An epithelial cell of the uterus. GO:0046328 regulation of JNK cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046328 regulation of SAPK cascade Any process that modulates the frequency, rate or extent of signal transduction mediated by the JNK cascade. GO:0061968 maintenance of left/right asymmetry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061968 The organization process that preserves the asymmetry in an organism's body plan or part of an organism with respect to the left and right halves. UBERON:0002489 coronal suture biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002489 frontoparietal suture|coronal suture of skull|fronto-parietal suture|sutura coronalis the dense, fibrous connective tissue joint between the tetrapod parietal bones and the frontal bone GO:0061967 establishment of left sidedness biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061967 The initial formation of the type asymmetry in an organism's body plan or part of an organism that established the pattern characteristic to its left side. GO:0061969 maintenance of left sidedness biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061969 The organization process that preserves the left sidedness in an organism's body plan or part of an organism with respect to the left and right halves. CHEBI:25858 1,7-dimethylxanthine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_25858 UBERON:0002485 prostate duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002485 duct of prostate|prostate gland duct|prostatic duct|duct of prostate gland|prostate duct The minute canals that pass the prostatic secretions to the urethra. CL:0002140 acinar cell of sebaceous gland biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002140 sebocyte A sebum secreting cell of the skin that secretes sebum into the hair follicles. GO:0046330 positive regulation of JNK cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046330 up-regulation of JNK cascade|upregulation of JNK cascade|up regulation of JNK cascade|activation of JNK cascade|stimulation of JNK cascade Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the JNK cascade. GO:1900408 negative regulation of cellular response to oxidative stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900408 downregulation of cellular response to oxidative stress|down regulation of adaptive response to oxidative stress|downregulation of adaptive response to oxidative stress|down-regulation of cellular response to oxidative stress|negative regulation of adaptive response to oxidative stress|down-regulation of adaptive response to oxidative stress|inhibition of cellular response to oxidative stress|inhibition of adaptive response to oxidative stress|down regulation of cellular response to oxidative stress Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to oxidative stress. GO:1900407 regulation of cellular response to oxidative stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900407 regulation of adaptive response to oxidative stress Any process that modulates the frequency, rate or extent of cellular response to oxidative stress. CHEBI:25863 pelargonidin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25863 OBO:GOCHE_38231 substance with phytotoxin role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_38231 OBO:GOCHE_38234 substance with DNA polymerase inhibitor role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_38234 GO:1900409 positive regulation of cellular response to oxidative stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900409 upregulation of adaptive response to oxidative stress|up regulation of cellular response to oxidative stress|activation of cellular response to oxidative stress|up regulation of adaptive response to oxidative stress|positive regulation of adaptive response to oxidative stress|up-regulation of cellular response to oxidative stress|activation of adaptive response to oxidative stress|up-regulation of adaptive response to oxidative stress|upregulation of cellular response to oxidative stress Any process that activates or increases the frequency, rate or extent of cellular response to oxidative stress. GO:1900404 positive regulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900404 up regulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter|upregulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter|stimulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter|up-regulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter|activation of DNA repair by positive regulation of transcription from RNA polymerase II promoter A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of DNA repair. GO:1900403 obsolete negative regulation of cellular amino acid biosynthetic process by negative regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900403 negative regulation of cellular amino acid biosynthesis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of amino acid biosynthetic process by negative regulation of transcription from RNA polymerase II promoter|negative regulation of cellular amino acid anabolism by negative regulation of transcription from RNA polymerase II promoter|negative regulation of cellular amino acid synthesis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of cellular amino acid formation by negative regulation of transcription from RNA polymerase II promoter OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of cellular amino acid biosynthetic process. CHEBI:60191 rhamnogalacturonan II biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60191 GO:1900406 obsolete regulation of conjugation with cellular fusion by regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900406 OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of conjugation with cellular fusion. CHEBI:60190 homogalacturonan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60190 CHEBI:25865 penicillanic acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25865 GO:1900405 obsolete regulation of cell separation after cytokinesis by regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900405 regulation of cytokinetic cell separation by regulation of transcription from RNA polymerase II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of cell separation after cytokinesis. GO:0046338 phosphatidylethanolamine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046338 phosphatidylethanolamine degradation|phosphatidylethanolamine catabolism|phosphatidylethanolamine breakdown The chemical reactions and pathways resulting in the breakdown of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine. GO:1900400 regulation of iron ion import into cell by regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900400 regulation of iron ion transport by regulation of transcription from RNA polymerase II promoter|regulation of iron import by regulation of transcription from RNA polymerase II promoter|regulation of iron ion import by regulation of transcription from RNA polymerase II promoter A regulation of transcription from RNA polymerase II promoter that results in regulation of iron ion import. CHEBI:60193 queuosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60193 CHEBI:60192 triacyl lipopeptide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60192 GO:0046337 phosphatidylethanolamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046337 phosphatidylethanolamine metabolism The chemical reactions and pathways involving phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine. It is a major structural phospholipid in mammalian systems. It tends to be more abundant than phosphatidylcholine in the internal membranes of the cell and is an abundant component of prokaryotic membranes. GO:1900402 obsolete regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900402 regulation of carbohydrate metabolism by regulation of transcription from RNA polymerase II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of carbohydrate metabolic process. GO:0046336 ethanolamine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046336 ethanolamine degradation|ethanolamine breakdown|ethanolamine catabolism The chemical reactions and pathways resulting in the breakdown of ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine). CHEBI:60195 cyclic peptide cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60195 GO:0046335 ethanolamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046335 ethanolamine biosynthesis|ethanolamine anabolism|ethanolamine synthesis|ethanolamine formation The chemical reactions and pathways resulting in the formation of ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine). GO:1900401 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1900401 CHEBI:60194 peptide cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60194 GO:0046334 octopamine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046334 octopamine degradation|octopamine breakdown|octopamine catabolism The chemical reactions and pathways resulting in the breakdown of octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol. The D enantiomer is about one-tenth as active as norepinephrine and is found in the salivary glands of Octopus and Eledone species. CHEBI:60197 bacteriochlorophyll c biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60197 GO:0046333 octopamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046333 octopamine metabolism The chemical reactions and pathways involving octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol. The D enantiomer is about one-tenth as active as norepinephrine and is found in the salivary glands of Octopus and Eledone species. CHEBI:60196 O-phospho peptide cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60196 GO:0046332 SMAD binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046332 Interacting selectively and non-covalently with a SMAD signaling protein. CHEBI:60199 acyl monophosphate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60199 GO:0046331 lateral inhibition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046331 Signaling between cells of equivalent developmental potential that results in these cells adopting different developmental fates. An example is the suppression by cells with a particular fate of the adoption of the same fate by surrounding cells. UBERON:0002470 autopod region biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002470 distal segment of limb|distal segment of free limb|autopodial element|autopodial segment|autopod|autopodium|distal free limb segment|autopodium region|autopodial limb segment|paw/hand/foot/hoof|manus/pes|paw|pod Terminal segment of free limb, immediately distal to the zeugopod region. The fully developed autopod consists of the autopod skeleton plus associated structures such as integument, muscle tissue, vasculature etc. The autopod is divided into mesopodial, metapodiual, and acropodial segments. Examples: human hand, mouse paw, human foot GO:0061951 establishment of protein localization to plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061951 The directed movement of a protein to a specific location in a plasma membrane. UBERON:0002472 stylopod biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002472 stylopodial limb segment|stylopodium|proximal free limb segment|proximal segment of free limb|propodium|proximal part of limb The proximal free limb segment. Includes as parts the stylopod skeleton. UBERON:0002471 zeugopod biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002471 zygopod|epipodium|zeugopod limb segment|middle segment of free limb|middle limb segment|middle part of limb|middle free limb segment|zeugopodium|zeugopodial limb segment|zygopodium The middle free limb segment, between the autopod and stylopod segments. Includes as parts the zeugopodial skeleton. Examples: There are two types of zeugopod: forelimb zeugopod (aka forearm), hindlimb zeugopod (aka crus). GO:0061950 negative regulation of premature acrosome loss biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061950 negative regulation of spontaneous acrosome loss Any process that stops, prevents or reduces the discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents. CHEBI:84153 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-1D-myo-inositol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84153 GO:0061953 mRNA (adenine-N1-)-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061953 Catalysis of the reaction: S-adenosyl-L-methionine + adenine in mRNA = S-adenosyl-L-homocysteine + N(1)-methyladenine in mRNA. CL:0002159 general ecto-epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002159 Epithelial cells derived from general body ectoderm and ectoderm placodes. GO:0061952 midbody abscission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061952 cell separation during cytokinesis|cytokinetic abscission The process by which the midbody, the cytoplasmic bridge that connects the two prospective daughter cells, is severed at the end of mitotic cytokinesis, resulting in two separate daughter cells. GO:0061955 positive regulation of actin filament depolymerization involved in acrosome reaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061955 Any process that increases the rate or exent of actin depolymerization as part of the acrosome reaction. This allows the acrosomal membrane and plasma membrane to fuse. GO:0046339 diacylglycerol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046339 diacylglycerol metabolism|diglyceride metabolism The chemical reactions and pathways involving diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group. GO:0061954 positive regulation of actin filament polymerization involved in sperm capacitation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061954 Any process that icreases the rate or extent of actin polymerization as part of sperm capacitation. This process prevents a spontaneous acrosome reaction. CHEBI:84150 4-hydroxy-6-(2-oxotridecyl)pyran-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84150 UBERON:0002478 orbitosphenoid biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002478 lesser wing of sphenoid bone|orbito-sphénocïde@fr|conchosphénocïde@fr|lesser wing of sphenoidal bone|orbitosphenoids|ala minor (os sphenoidale)|orbitosphenoid bone|ala minor ossis sphenoidalis|alae parvae|ingrassia's process|lesser wing of sphenoid the bone that is situated in the orbit on either side of the presphenoid; it generally forms a part of the sphenoid in the adult, and may be independent in the young GO:0061957 NVT complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061957 A protein complex that is capable of contributing to protein localization by the NVT pathway. In fission yeast, the Nvt complex consists of Ape2, Lap2 and Nbr1. GO:0061956 penetration of cumulus oophorus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061956 penetration of cumulus mass|penetration of cumulus cells layer The infiltration by sperm of the cumulus oophorus to reach the oocyte. The process involves digestive enzymes from a modified lysosome called the acrosome, situated at the head of the sperm. GO:0061959 response to (R)-carnitine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061959 response to L-carnitine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an (R)-carnitine stimulus. UBERON:0002473 intercerebral commissure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002473 inter-hemispheric commissure|commissure of cerebrum|interhemispheric commissure A commissure that connects the two cerebral hemispheres. Examples: anterior commissure, corpus callosum. CL:0002153 corneocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002153 The dead keratin-filled squamous cell of the stratum corneum. This cell type lacks a nucleus. GO:0046341 CDP-diacylglycerol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046341 CDP-diacylglycerol metabolism The chemical reactions and pathways involving CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate. It is a common intermediate in phospholipid biosynthesis. GO:1900419 regulation of cellular alcohol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900419 Any process that modulates the frequency, rate or extent of cellular alcohol catabolic process. GO:0046340 diacylglycerol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046340 diglyceride catabolism|diacylglycerol catabolism|diacylglycerol degradation|diacylglycerol breakdown The chemical reactions and pathways resulting in the breakdown of diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group. GO:1900418 obsolete positive regulation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900418 upregulation of purine nucleotide formation by positive regulation of transcription from RNA polymerase II promoter|up regulation of purine nucleotide anabolism by positive regulation of transcription from RNA polymerase II promoter|upregulation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|upregulation of purine nucleotide biosynthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of purine nucleotide anabolism by positive regulation of transcription from RNA polymerase II promoter|up regulation of purine nucleotide synthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of purine nucleotide synthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of purine nucleotide formation by positive regulation of transcription from RNA polymerase II promoter|activation of purine nucleotide anabolism by positive regulation of transcription from RNA polymerase II promoter|up-regulation of purine nucleotide biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|positive regulation of purine nucleotide formation by positive regulation of transcription from RNA polymerase II promoter|activation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|activation of purine nucleotide synthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of purine nucleotide anabolism by positive regulation of transcription from RNA polymerase II promoter|activation of purine nucleotide formation by positive regulation of transcription from RNA polymerase II promoter|activation of purine nucleotide biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of purine nucleotide synthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of purine nucleotide biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of purine nucleotide formation by positive regulation of transcription from RNA polymerase II promoter|upregulation of purine nucleotide anabolism by positive regulation of transcription from RNA polymerase II promoter|up regulation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up regulation of purine nucleotide biosynthesis by positive regulation of transcription from RNA polymerase II promoter|upregulation of purine nucleotide synthesis by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of purine nucleotide biosynthetic process. CHEBI:25830 p-quinones biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25830 GO:1900415 obsolete regulation of fungal-type cell wall biogenesis by regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900415 regulation of chitin- and beta-glucan-containing cell wall biogenesis by regulation of transcription from RNA polymerase II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of fungal-type cell wall biogenesis. CHEBI:25835 hexadecanoate ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_25835 GO:1900414 obsolete regulation of cytokinesis by regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900414 OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of cytokinesis. GO:1900417 obsolete negative regulation of transmembrane transport by negative regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900417 OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of transmembrane transport. GO:1900416 obsolete regulation of 4,6-pyruvylated galactose residue biosynthetic process by regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900416 OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of 4,6-pyruvylated galactose residue biosynthetic process. GO:0046349 amino sugar biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046349 amino sugar synthesis|amino sugar formation|amino sugar biosynthesis|aminosaccharide biosynthesis|aminosaccharide biosynthetic process|amino sugar anabolism The chemical reactions and pathways resulting in the formation of any amino sugar, sugars containing an amino group in place of a hydroxyl group. GO:1900411 obsolete regulation of histone acetylation by regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900411 OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of histone acetylation. CL:0002129 regular atrial cardiac myocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002129 atrial cardiac muscle cell|atrial myocyte|regular cardiac muscle cell of atrium|regular atrial cardiac muscle fiber Regular cardiac myocyte of a cardiac atrium. GO:1900410 obsolete regulation of histone modification by regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900410 OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of histone modification. GO:0046348 amino sugar catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046348 amino sugar catabolism|aminosaccharide catabolic process|amino sugar degradation|amino sugar breakdown|aminosaccharide catabolism The chemical reactions and pathways resulting in the breakdown of any amino sugar, sugars containing an amino group in place of a hydroxyl group. GO:1900413 obsolete positive regulation of phospholipid biosynthetic process by positive regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900413 positive regulation of phospholipid biosynthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of phospholipid synthesis by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of phospholipid biosynthetic process. GO:0046347 mannosamine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046347 mannosamine anabolism|mannosamine synthesis|mannosamine biosynthesis|mannosamine formation The chemical reactions and pathways resulting in the formation of mannosomine, 2-amino-2-deoxymannose; the D-isomer is a constituent of neuraminic acids as well as mucolipids and mucoproteins. GO:0046346 mannosamine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046346 mannosamine degradation|mannosamine breakdown|mannosamine catabolism The chemical reactions and pathways resulting in the breakdown of mannosomine, 2-amino-2-deoxymannose; the D-isomer is a constituent of neuraminic acids as well as mucolipids and mucoproteins. GO:1900412 obsolete regulation of histone methylation by regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900412 OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of histone methylation. GO:0046345 abscisic acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046345 abscisic acid breakdown|abscisic acid catabolism|abscisic acid degradation The chemical reactions and pathways resulting in the breakdown of abscisic acid, 5-(1-hydroxy-2,6,6,trimethyl-4-oxocyclohex-2-en-1-y1)-3-methylpenta-2,4-dienoic acid. GO:0046344 ecdysteroid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046344 ecdysteroid catabolism|ecdysteroid degradation|ecdysteroid breakdown The chemical reactions and pathways resulting in the breakdown of ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development. GO:0061980 regulatory RNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061980 Interacting selectively and non-covalently with a small regulatory RNA, a short RNA (usually 50-200 nt long) that is either independently transcribed or processed from a longer RNA by an RNAse enzyme. GO:0046343 streptomycin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046343 streptomycin metabolism The chemical reactions and pathways involving streptomycin, a commonly used antibiotic in cell culture media. It acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome. GO:0046342 CDP-diacylglycerol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046342 CDP-diacylglycerol catabolism|CDP-diacylglycerol degradation|CDP-diacylglycerol breakdown The chemical reactions and pathways resulting in the breakdown of CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate. CHEBI:84169 4-hydroxy-6-heptadecylpyran-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84169 GO:0061982 meiosis I cell cycle process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061982 first meiotic cell division A process that contributes to the first meiotic division. The first meiotic division is the reductive division resulting in the separation of homologous chromosome pairs. CL:0002122 B220-positive CD38-positive IgG-negative class switched memory B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002122 A B220-positive CD38-positive IgG-negative memory B cell is a CD38-positive IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype B220-positive, CD38-positive, and IgG-negative. CHEBI:84168 4-hydroxy-6-pentadecylpyran-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84168 CHEBI:11222 1-[(4-amino-2-methylpyrimidin-5-yl)methyl]pyridinium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_11222 CL:0002121 CD24-negative CD38-negative IgG-negative class switched memory B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002121 A CD24-negative CD38-negative IgG-negative memory B cell is a CD38-negative IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD24-negative, CD38-negative, and IgG-negative. GO:0061981 3-hydroxykynureninase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061981 RHEA:25143 Catalysis of the reaction: L-3-hydroxykynurenine + H2O = 3-hydroxyanthranilate + L-alanine. CHEBI:84167 2-methoxy-3-methyl-6-all-trans-polyprenylhydroquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84167 CL:0002124 CD27-positive gamma-delta T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002124 gd27-positive|gammadelta27-positive A circulating gamma-delta T cell that is CD27-positive and capable of producing IFN-gamma. CHEBI:84166 2-methoxy-6-all-trans-polyprenylhydroquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84166 GO:0061984 catabolite repression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061984 A process in which the presence of one nutrient source leads to a decrease in the frequency, rate, or extent of processes involved in the metabolism of other nutrient sources. UBERON:0002460 vesical vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002460 vesical veins set|vesical veins|venae vesicales A tributary of the iliac vein that drains the urinary bladder. CL:0002123 B220-low CD38-positive IgG-negative class switched memory B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002123 A B220-low CD38-positive IgG-negative memory B cell is a CD38-positive IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype B220-low, CD38-positive, and IgG-positive. GO:0061983 meiosis II cell cycle process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061983 second meiotic division A process that coontributes to the second meiotic division. The second meiotic division separates chromatids resulting in a haploid number of chromosomes. GO:0061986 negative regulation of transcription by glucose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061986 Any process involving glucose that decreases the frequency, rate or extent or transcription. GO:0071309 cellular response to phylloquinone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071309 cellular response to vitamin K1 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phylloquinone (vitamin K1) stimulus. CL:0002126 CD25-positive, CD27-positive immature gamma-delta T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002126 A CD25-positive, CD27-positive immature gamma-delta T cell found in the thymus that has an immature phenotype (i.e. CD24-high, CD25-high, CD62L-high, CD44-high, CD2-low, CD5-low). GO:0071308 cellular response to menaquinone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071308 cellular response to vitamin K2|cellular response to menatetrenone Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menaquinone (vitamin K2) stimulus. GO:0061985 carbon catabolite repression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061985 A process in which the presence of one carbon source leads to the modulation of the frequency, rate, or extent of the metabolism of other carbon sources. CL:0002125 CD27-negative gamma-delta T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002125 gammadelta-17 cells A circulating gamma-delta T cell that expresses RORgamma(t), is CD27-negative and is capable of IL-17 secretion. CHEBI:84163 anthocyanidin 3-O-(6-O-malonyl-beta-D-glucoside) betaine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84163 GO:0071307 cellular response to vitamin K biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071307 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin K stimulus. CHEBI:84162 (2E,6E)-farnesoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84162 GO:0061988 karyosome formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061988 The chromosome organization process in which meiotic chromosomes in the germ cell nucleus cluster together to form a compact spherical structure called the karyosome. CL:0002127 innate effector T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002127 A T cell with a receptor of limited diversity that is capable of immediate effector functions upon stimulation. GO:0071306 cellular response to vitamin E biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071306 cellular response to O-Acetyl-alpha-tocopherol|cellular response to DL-alpha-tocopherol acetate|cellular response to DL-alpha-tocopheryl acetate Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin E stimulus. GO:0061987 negative regulation of transcription from RNA polymerase II promoter by glucose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061987 Any process involving glucose that decreases the frequency, rate or extent or transcription from an RNA polymerase II promoter. GO:0071305 cellular response to vitamin D biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071305 cellular response to calciferol|cellular response to ergocalciferol|cellular response to cholecalciferol Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus. SO:0001669 RNApol_II_core_promoter biolink:SequenceFeature go-plus http://purl.obolibrary.org/obo/SO_0001669 RNApol II core promoter The minimal portion of the promoter required to properly initiate transcription in RNA polymerase II transcribed genes. UBERON:0002466 intestine secretion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002466 succus entericus|intestinal juice|intestinal secretion Clear to pale yellow watery secretions from the glands lining the small intestine walls. Secretion is stimulated by the mechanical pressure of partly digested food in the intestine. GO:0071304 cellular response to vitamin B6 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071304 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B6 stimulus. Vitamin B6 encompasses pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate. GO:0061989 sperm karyosome formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061989 The chromosome organization process in which meiotic chromosomes in the spem nucleus cluster together to form a compact spherical structure called the karyosome. CHEBI:25838 palmitoyl amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25838 UBERON:0002469 esophagus mucosa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002469 oesophagus mucosa|mucous membrane of esophagus|esophageal mucous membrane|mucosa of esophagus|esophageal mucosa|oesophagus mucous membrane|esophagus mucosa|tunica mucosa esophagi|oesophageal mucosa|lamina muscularis mucosae oesophageae|tunica mucosa oesophagi|tunica mucosa oesophageae|muscularis mucosae of oesophagus|esophagus mucous membrane|tunica mucosa oesophagi|mucosa of oesophagus|mucous membrane of oesophagus A mucosa that is part of a esophagus [Automatically generated definition]. GO:0071303 cellular response to vitamin B3 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071303 cellular response to nicotinamide|cellular response to niacin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B3 stimulus. GO:0071302 cellular response to vitamin B2 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071302 cellular response to riboflavin Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B2 stimulus. CHEBI:49807 lead(2+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49807 GO:0071301 cellular response to vitamin B1 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071301 cellular response to thiamin|cellular response to thiamine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B1 stimulus. GO:0071300 cellular response to retinoic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071300 cellular response to vitamin A acid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus. UBERON:0002465 lymphoid system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002465 lymphatic circulatory system|lymphatic system|lymphatic drainage system|systema lymphoideum The lymphatic system in vertebrates is a network of conduits that carry a clear fluid called lymph. It also includes the lymphoid tissue through which the lymph travels. Lymphoid tissue is found in many organs, particularly the lymph nodes, and in the lymphoid follicles associated with the digestive system such as the tonsils. The system also includes all the structures dedicated to the circulation and production of lymphocytes, which includes the spleen, thymus, bone marrow and the lymphoid tissue associated with the digestive system[WP]. CL:0002120 CD24-positive CD38-negative IgG-negative class switched memory B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002120 An CD24-positive CD38-negative IgG-negative memory B cell is a CD38-negative IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD24-positive, CD38-negative, and IgG-negative. UBERON:0002464 nerve trunk biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002464 trunk of nerve|trunk of peripheral nerve|peripheral nerve trunk CHEBI:25842 palmityl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_25842 GO:0046352 disaccharide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046352 disaccharide catabolism|disaccharide degradation|disaccharide breakdown The chemical reactions and pathways resulting in the breakdown of disaccharides, sugars composed of two monosaccharide units. GO:0046351 disaccharide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046351 disaccharide formation|disaccharide biosynthesis|disaccharide anabolism|disaccharide synthesis The chemical reactions and pathways resulting in the formation of disaccharides, sugars composed of two monosaccharide units. GO:1900429 negative regulation of filamentous growth of a population of unicellular organisms biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900429 downregulation of filamentous growth of a population of unicellular organisms|down-regulation of filamentous growth of a population of unicellular organisms|inhibition of filamentous growth of a population of unicellular organisms|down regulation of filamentous growth of a population of unicellular organisms Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms. CHEBI:25840 palmitoyl-L-cysteine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25840 GO:0046350 galactosaminoglycan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046350 galactosaminoglycan metabolism The chemical reactions and pathways involving galactosaminoglycans, any one of a group of polysaccharides that contain amino sugars derived from the galactose. GO:1900426 positive regulation of defense response to bacterium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900426 upregulation of defence response to bacteria|up-regulation of defense response to bacterium|activation of resistance response to pathogenic bacterium|positive regulation of defense response to bacterium, incompatible interaction|up regulation of defence response to bacterium|positive regulation of defense response to bacteria|positive regulation of defence response to bacterium|upregulation of antibacterial peptide activity|up regulation of defense response to bacteria|upregulation of defense response to bacterium|up-regulation of defence response to bacteria|activation of defence response to bacterium|activation of resistance response to pathogenic bacteria|up-regulation of antibacterial peptide activity|activation of defence response to bacteria|up-regulation of defence response to bacterium|upregulation of defense response to bacteria|up regulation of defense response to bacterium|positive regulation of defence response to bacteria|activation of defense response to bacterium|activation of antibacterial peptide activity|up regulation of defence response to bacteria|upregulation of defence response to bacterium|up-regulation of defense response to bacteria|positive regulation of antibacterial peptide activity|up regulation of antibacterial peptide activity|activation of defense response to bacteria Any process that activates or increases the frequency, rate or extent of defense response to bacterium. GO:1900425 negative regulation of defense response to bacterium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900425 inhibition of defense response to bacterium, incompatible interaction|inhibition of resistance response to pathogenic bacteria|inhibition of response to pathogenic bacteria (incompatible interaction)|down regulation of antibacterial peptide activity|inhibition of defence response to bacteria|negative regulation of defense response to bacterium, incompatible interaction|down-regulation of defence response to bacterium|negative regulation of defence response to bacterium|downregulation of defense response to bacteria|inhibition of antibacterial peptide activity|down regulation of defense response to bacterium|down regulation of defense response to bacteria|inhibition of resistance response to pathogenic bacterium|negative regulation of defence response to bacteria|down-regulation of defence response to bacteria|downregulation of defense response to bacterium|inhibition of defence response to pathogenic bacterium, incompatible interaction|inhibition of response to pathogenic bacterium (incompatible interaction)|inhibition of defense response to bacteria|inhibition of defence response to bacterium|down-regulation of antibacterial peptide activity|negative regulation of antibacterial peptide activity|downregulation of defence response to bacteria|down-regulation of defense response to bacterium|down regulation of defence response to bacterium|down regulation of defence response to bacteria|downregulation of defence response to bacterium|downregulation of antibacterial peptide activity|negative regulation of defense response to bacteria|down-regulation of defense response to bacteria|inhibition of defense response to bacterium|inhibition of defence response to pathogenic bacteria, incompatible interaction Any process that stops, prevents or reduces the frequency, rate or extent of defense response to bacterium. CHEBI:25845 pantetheines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25845 UBERON:0002448 fungiform papilla biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002448 fungiform papillae set|fungiform papillae|fungiform papilla of tongue|papillae fungiformes Any of the mushroom-shaped papillae, which have a single taste bud at the tip, located mostly on the dorsal anterior portion of the tongue GO:1900428 regulation of filamentous growth of a population of unicellular organisms biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900428 Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms. GO:1900427 obsolete regulation of cellular response to oxidative stress by regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900427 regulation of adaptive response to oxidative stress by regulation of transcription from RNA polymerase II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of cellular response to oxidative stress. GO:1900422 obsolete positive regulation of cellular alcohol catabolic process by positive regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900422 up regulation of cellular alcohol catabolic process by positive regulation of transcription from RNA polymerase II promoter|upregulation of cellular alcohol catabolic process by positive regulation of transcription from RNA polymerase II promoter|up-regulation of cellular alcohol catabolic process by positive regulation of transcription from RNA polymerase II promoter|activation of cellular alcohol catabolic process by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of cellular alcohol catabolic process. GO:0046359 butyrate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046359 butyrate breakdown|butyrate catabolism|butanoic acid catabolism|butanoic acid degradation|butanoic acid breakdown|butanoic acid catabolic process|butyrate degradation The chemical reactions and pathways resulting in the breakdown of butyrate, the anion of butyric acid. GO:1900421 positive regulation of cellular alcohol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900421 up regulation of cellular alcohol catabolic process|upregulation of cellular alcohol catabolic process|up-regulation of cellular alcohol catabolic process|activation of cellular alcohol catabolic process Any process that activates or increases the frequency, rate or extent of cellular alcohol catabolic process. PR:000021003 urokinase-type plasminogen activator proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000021003 PLAU/ClvPrd A urokinase-type plasminogen activator that has been processed by proteolytic cleavage. GO:1900424 regulation of defense response to bacterium biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900424 regulation of antibacterial peptide activity|regulation of defence response to pathogenic bacterium, incompatible interaction|regulation of defence response to pathogenic bacteria, incompatible interaction|regulation of defense response to bacteria|regulation of resistance response to pathogenic bacterium|regulation of resistance response to pathogenic bacteria|regulation of defence response to bacterium, incompatible interaction|regulation of defense response to bacterium, incompatible interaction|regulation of defence response to bacteria|regulation of defence response to bacterium Any process that modulates the frequency, rate or extent of defense response to bacterium. GO:0046358 butyrate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046358 butanoic acid synthesis|butyrate biosynthesis|butanoic acid formation|butyrate anabolism|butyrate synthesis|butanoic acid biosynthetic process|butanoic acid biosynthesis|butyrate formation|butanoic acid anabolism The chemical reactions and pathways resulting in the formation of butyrate, the anion of butyric acid. GO:1900423 obsolete positive regulation of mating type switching by positive regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900423 up regulation of mating type switching by positive regulation of transcription from RNA polymerase II promoter|activation of mating type switching by positive regulation of transcription from RNA polymerase II promoter|stimulation of mating type switching by positive regulation of transcription from RNA polymerase II promoter|up-regulation of mating type switching by positive regulation of transcription from RNA polymerase II promoter|upregulation of mating type switching by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of mating type switching. GO:0046357 galactarate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046357 galactarate synthesis|galactarate formation|D-galactarate biosynthesis|D-galactarate biosynthetic process|galactarate biosynthesis|D-galactarate anabolism|D-galactarate synthesis|D-galactarate formation|galactarate anabolism The chemical reactions and pathways resulting in the formation of galactarate, the anion of galactaric acid. GO:0046356 acetyl-CoA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046356 acetyl-CoA degradation|acetyl-CoA breakdown|acetyl-CoA catabolism The chemical reactions and pathways resulting in the breakdown of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated. GO:0046355 mannan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046355 mannan catabolism|mannan degradation|mannan breakdown The chemical reactions and pathways resulting in the breakdown of mannan, the main hemicellulose of soft (coniferous) wood, made up of D-mannose, D-glucose and D-galactose. GO:0046354 mannan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046354 mannan synthesis|mannan formation|mannan biosynthesis|mannan anabolism The chemical reactions and pathways resulting in the formation of mannan, the main hemicellulose of soft (coniferous) wood, made up of D-mannose, D-glucose and D-galactose. GO:1900420 negative regulation of cellular alcohol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900420 down-regulation of cellular alcohol catabolic process|downregulation of cellular alcohol catabolic process|down regulation of cellular alcohol catabolic process|inhibition of cellular alcohol catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of cellular alcohol catabolic process. GO:0046353 aminoglycoside 3-N-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046353 EC:2.3.1.60|EC:2.3.1.81|MetaCyc:GENTAMICIN-3-N-ACETYLTRANSFERASE-RXN|MetaCyc:AMINOGLYCOSIDE-N3-ACETYLTRANSFERASE-RXN acetyl-CoA:gentamicin-C N3'-acetyltransferase activity|gentamycin acetyltransferase I|gentamicin-(3)-N-acetyltransferase activity|aminoglycoside acetyltransferase AAC(3)-1|gentamycin 3'-N-acetyltransferase activity|gentamicin acetyltransferase I activity|3-N-aminoglycoside acetyltransferase activity|3'-aminoglycoside acetyltransferase activity|acetyl-CoA:2-deoxystreptamine-antibiotic N3'-acetyltransferase activity|aminoglycoside acetyltransferase AAC(3)-I activity|gentamicin 3'-N-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + 3-N-acetylaminoglycoside. This is acetylation of the 3-amino group of the central deoxystreptamine ring. GO:0061971 replacement bone morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061971 The process in which bones are generated and organized as a result of the conversion of another structural tissue into bone. GO:0061970 maintenance of right sidedness biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061970 The organization process that preserves the right sidedness in an organism's body plan or part of an organism with respect to the left and right halves. CL:0002132 stromal cell of ovary biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002132 ovarian stromal cell A stomal cell of the ovary UBERON:0002450 decidua biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002450 maternal decidual layer|maternal placenta|decidous membrane|extraembryonic part of placenta|maternal part of placenta|uterine decidua|placenta maternal decidual layer|endometrium|decidua basalis|extraembryonic placenta The maternal uterine-derived portion of the placenta GO:0061973 membrane bone morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061973 The process in which bone which forms deep in the organism are generated and organized. CHEBI:84177 14-HPDHE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84177 GO:0061972 dermal bone morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061972 The process in which bone which forms superficially in the organism are generated and organized. CHEBI:84176 12-methyloctadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84176 GO:0061975 articular cartilage development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061975 articular cartilage of joint development The process whose specific outcome is the progression of articular cartilage over time, from its formation to the mature structure. CHEBI:84175 2-methylhexadecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84175 GO:0061974 perichondral bone morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061974 The process in which bones are generated and organized as a result of the conversion of initial connective tissue surrounding cartilage into bone. CHEBI:84174 12-HPE(8,10,14)TrE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84174 GO:0061977 hip joint articular cartilage development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061977 The process whose specific outcome is the progression of hip joint articular cartilage over time, from its formation to the mature structure. CL:0002139 endothelial cell of vascular tree biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002139 cubodial endothelial cell of vascular tree|vascular endothelial cell An endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels. CHEBI:84173 4-hydroxy-6-(2-oxohenicosyl)pyran-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84173 GO:0061976 temporomandibular joint articular cartilage development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061976 The process whose specific outcome is the progression of temporomandibular joint articular cartilage over time, from its formation to the mature structure. CL:0002138 endothelial cell of lymphatic vessel biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002138 LEC|lymphatic endothelial cell A endothelial cell of a lymphatic vessel. The border of the oak leaf-shaped endothelial cell of initial lymphatics are joined by specialized buttons. The discontinuous feature of buttons distinguishes them from zippers in collecting lymphatics, but both types of junctions are composed of proteins typical of adherens junctions and tight junctions found in the endothelium of blood vessels. Buttons seal the sides of flaps of the oak leaf-shaped endothelial cell, leaving open the tips of flaps as routes for fluid entry without disassembly and reformation of intercellular junctions. CHEBI:84172 4-hydroxy-6-(2-oxononadecyl)pyran-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84172 GO:0061979 femoral head articular cartilage development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061979 The process whose specific outcome is the progression of femoral head articular cartilage over time, from its formation to the mature structure. UBERON:0002456 internal thoracic artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002456 arteria thoracica interna|internal thoracic mammary artery|arteria mammaria interna|internal mammary artery|mammary artery An artery that supplies the anterior chest wall and the breasts. It is a paired artery, with one running along each side of the sternum, to continue after its bifurcation as the superior epigastric and musculophrenic arteries. [WP,unvetted]. CHEBI:84171 4-hydroxy-6-(2-oxoheptadecyl)pyran-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84171 GO:0061978 mandibular condyle articular cartilage development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061978 The process whose specific outcome is the progression of mandibular joint condyle articular cartilage over time, from its formation to the mature structure. CHEBI:84170 4-hydroxy-6-nonadecylpyran-2-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84170 UBERON:0002458 spinal artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002458 spinal arteries Arteries that supply the spinal cord. CHEBI:25848 pantothenic acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25848 UBERON:0002457 intersomitic artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002457 intersegmental arteries|intersegmental artery The small branching sprouts of the dorsal aorta that grow across the medial surface of the somite, turn right angles to grow over that surface and then fuse with other sprouts and form the vertebral arteries adjacent to the neural tube; the intersomitic arteries supply the body wall and persist in the adult as the posterior intercostal, subcostal and the lumbar arteries SO:0001659 promoter_element biolink:SequenceFeature go-plus http://purl.obolibrary.org/obo/SO_0001659 promoter element An element that can exist within the promoter region of a gene. SO:0001654 nucleotide_to_protein_binding_site biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0001654 nucleotide to protein binding site A binding site that, in the nucleotide molecule, interacts selectively and non-covalently with polypeptide residues. UBERON:0002451 endometrial gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002451 glandulae uterinae|endometrial gland|endometrial mucuous gland|endometrium gland|glandulae uterinae|uterine gland The mucous secreting gland associated with the mucuous membrane lining the uterus. CL:0002131 regular ventricular cardiac myocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002131 ventricular myocyte|regular ventricular cardiac muscle fiber|ventricular cardiac muscle cell|regular cardiac muscle cell of ventricle Regular cardiac myocyte of a cardiac ventricle. GO:0046363 ribitol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046363 ribitol catabolism|ribitol degradation|ribitol breakdown The chemical reactions and pathways resulting in the breakdown of ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose. GO:0046362 ribitol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046362 ribitol formation|ribitol biosynthesis|ribitol anabolism|ribitol synthesis The chemical reactions and pathways resulting in the formation of ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose. GO:0046361 2-oxobutyrate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046361 alpha-ketobutyrate metabolic process|alpha-ketobutyrate metabolism|2-oxobutyrate metabolism The chemical reactions and pathways involving 2-oxobutyrate, the anion of the organic acid 2-oxobutyric acid, which contains a ketone group on carbon 2. GO:0046360 2-oxobutyrate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046360 2-oxobutyrate anabolism|2-oxobutyrate synthesis|2-oxobutyrate formation|alpha-ketobutyrate biosynthesis|alpha-ketobutyrate biosynthetic process|2-oxobutyrate biosynthesis The chemical reactions and pathways resulting in the formation of 2-oxobutyrate, the anion of the organic acid 2-oxobutyric acid, which contains a ketone group on carbon 2. GO:1900437 regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900437 Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to chemical stimulus. GO:1900436 positive regulation of filamentous growth of a population of unicellular organisms in response to starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900436 up regulation of filamentous growth of a population of unicellular organisms in response to starvation|activation of filamentous growth of a population of unicellular organisms in response to starvation|up-regulation of filamentous growth of a population of unicellular organisms in response to starvation|upregulation of filamentous growth of a population of unicellular organisms in response to starvation Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation. CHEBI:25812 ozone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_25812 GO:1900439 positive regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900439 upregulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus|up-regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus|activation of filamentous growth of a population of unicellular organisms in response to chemical stimulus|up regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to chemical stimulus. GO:1900438 negative regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900438 down-regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus|downregulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus|down regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus|inhibition of filamentous growth of a population of unicellular organisms in response to chemical stimulus Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to chemical stimulus. CHEBI:25810 oxopurine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25810 GO:1900433 positive regulation of filamentous growth of a population of unicellular organisms in response to heat biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900433 activation of filamentous growth of a population of unicellular organisms in response to heat|up-regulation of filamentous growth of a population of unicellular organisms in response to heat|upregulation of filamentous growth of a population of unicellular organisms in response to heat|up regulation of filamentous growth of a population of unicellular organisms in response to heat Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to heat. CL:0002108 CD38-negative IgG memory B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002108 A CD38-negative IgG memory B cell is a IgG-positive class switched memory B cell that has class switched and expresses IgG on the cell surface with the phenotype CD38-negative, IgD-negative, and IgG-positive. GO:1900432 negative regulation of filamentous growth of a population of unicellular organisms in response to heat biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900432 down-regulation of filamentous growth of a population of unicellular organisms in response to heat|inhibition of filamentous growth of a population of unicellular organisms in response to heat|down regulation of filamentous growth of a population of unicellular organisms in response to heat|downregulation of filamentous growth of a population of unicellular organisms in response to heat Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to heat. CL:0002107 IgD-negative CD38-positive IgG memory B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002107 An IgD-negative CD38-positive IgG memory B cell is a CD38-positive IgG-positive that has class switched and lacks expression of IgD on the cell surface with the phenotype IgD-negative, CD38-positive, and IgG-positive. GO:1900435 obsolete negative regulation of filamentous growth of a population of unicellular organisms in response to starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900435 down-regulation of filamentous growth of a population of unicellular organisms in response to starvation|inhibition of filamentous growth of a population of unicellular organisms in response to starvation|down regulation of filamentous growth of a population of unicellular organisms in response to starvation|downregulation of filamentous growth of a population of unicellular organisms in response to starvation OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation. GO:0046369 galactose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046369 galactose anabolism|galactose synthesis|galactose formation|galactose biosynthesis The chemical reactions and pathways resulting in the formation of galactose, the aldohexose galacto-hexose. GO:1900434 regulation of filamentous growth of a population of unicellular organisms in response to starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900434 Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation. CL:0002109 B220-positive CD38-positive naive B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002109 CD38+B220+ naive B cell|B220+CD38+ naive B-cell|CD38+B220+ naive B lymphocyte|B220-positive CD38-positive naive B lymphocyte|B220+CD38+ naive B-lymphocyte|B220+CD38+ naive B cell|B220-positive CD38-positive naive B-cell|CD38+B220+ naive B-cell|B220+CD38+ naive B lymphocyte|CD38+B220+ naive B-lymphocyte|B220-positive CD38-positive naive B-lymphocyte A B220-positive CD38-positive naive B cell is a CD38-positive naive B cell that has the phenotype B220-positive, CD38-positive, surface IgD-positive, surface IgM-positive, and CD27-negative, and that has not yet been activated by antigen in the periphery. GO:0046368 GDP-L-fucose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046368 GDP-L-fucose metabolism The chemical reactions and pathways involving GDP-L-fucose, a substance composed of L-fucose in glycosidic linkage with guanosine diphosphate. GO:0046367 allose catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046367 allose degradation|allose breakdown|allose catabolism The chemical reactions and pathways resulting in the breakdown of allose, allo-hexose, an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3. GO:0046366 allose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046366 allose anabolism|allose synthesis|allose formation|allose biosynthesis The chemical reactions and pathways resulting in the formation of allose, allo-hexose, an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3. GO:0046365 monosaccharide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046365 monosaccharide breakdown|monosaccharide catabolism|monosaccharide degradation The chemical reactions and pathways resulting in the breakdown of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. GO:1900431 regulation of filamentous growth of a population of unicellular organisms in response to heat biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900431 Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to heat. GO:1900430 positive regulation of filamentous growth of a population of unicellular organisms biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900430 upregulation of filamentous growth of a population of unicellular organisms|up regulation of filamentous growth of a population of unicellular organisms|activation of filamentous growth of a population of unicellular organisms|up-regulation of filamentous growth of a population of unicellular organisms Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms. GO:0046364 monosaccharide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046364 monosaccharide anabolism|monosaccharide synthesis|monosaccharide formation|monosaccharide biosynthesis The chemical reactions and pathways resulting in the formation of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. CHEBI:84189 L-threonine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84189 CL:0002102 CD38-negative naive B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002102 CD38- naive B-cell|CD38- naive B-lymphocyte|CD38-negative naive B lymphocyte|CD38- naive B cell|CD38- naive B lymphocyte|CD38-negative naive B-cell|CD38-negative naive B-lymphocyte A CD38-negative naive B cell is a mature B cell that has the phenotype CD38-negative, surface IgD-positive, surface IgM-positive, and CD27-negative, that has not yet been activated by antigen in the periphery. CL:0002101 CD38-positive naive B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002101 CD38-positive naive B-lymphocyte|CD38+ naive B-cell|CD38+ naive B-lymphocyte|CD38-positive naive B lymphocyte|CD38+ naive B cell|CD38+ naive B lymphocyte|CD38-positive naive B-cell A CD38-positive naive B cell is a mature B cell that has the phenotype CD38-positive, surface IgD-positive, surface IgM-positive, and CD27-negative, and that has not yet been activated by antigen in the periphery. CHEBI:84187 2-epi-5-epi-valiolone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84187 CL:0002104 IgG-negative double negative memory B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002104 IgG- double negative memory B cell|IgG-negative double negative memory B-lymphocyte|IgG- dn memory B cell|IgG- double negative memory B lymphocyte|IgG- dn memory B lymphocyte|IgG-negative dn memory B-cell|IgG-negative dn memory B-lymphocyte|IgG-negative double negative memory B lymphocyte|IgG- double negative memory B-cell|IgG- dn memory B-cell|IgG- double negative memory B-lymphocyte|IgG-negative dn memory B cell|IgG- dn memory B-lymphocyte|IgG-negative dn memory B lymphocyte|IgG-negative double negative memory B-cell An IgG-negative double negative memory B cell is a double negative memory B cell with the phenotype IgG-negative, IgD-negative, and CD27-negative. CHEBI:84186 L-proline derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84186 CL:0002103 IgG-positive double negative memory B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002103 IgG+ dn memory B cell|IgG+ double negative memory B cell|IgG+ dn memory B lymphocyte|IgG+ double negative memory B lymphocyte|IgG-positive double negative memory B lymphocyte|IgG-positive dn memory B-cell|IgG-positive dn memory B-lymphocyte|IgG+ dn memory B-cell|IgG+ double negative memory B-cell|IgG+ dn memory B-lymphocyte|IgG+ double negative memory B-lymphocyte|IgG-positive double negative memory B-cell|IgG-positive dn memory B cell|IgG-positive double negative memory B-lymphocyte|IgG-positive dn memory B lymphocyte An IgG-positive double negative memory B cell is a double negative memory B cell with the phenotype IgG-positive, IgD-negative, and CD27-negative. CHEBI:84185 D-proline derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84185 GO:0071329 cellular response to sucrose stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071329 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus. CL:0002106 IgD-positive CD38-positive IgG memory B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002106 An IgD-positive CD38-positive IgG memory B cell is a CD38-positive IgG-positive class switched memory B cell that has class switched and expresses IgD on the cell surface with the phenotype IgD-positive, CD38-positive, and IgG-positive. CHEBI:84184 3-methylundecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84184 GO:0071328 cellular response to maltose stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071328 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a maltose stimulus. CL:0002105 CD38-positive IgG memory B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002105 CD38-positive IgG memory B lymphocyte|CD38+ IgG memory B-cell|CD38+ IgG memory B-lymphocyte|CD38-positive IgG memory B-cell|CD38-positive IgG memory B-lymphocyte|CD38+ IgG memory B cell|CD38+ IgG memory B lymphocyte A CD38-positive IgG memory B cell is a class switched memory B cell that expresses IgG on the cell surface with the phenotype CD38-positive and IgG-positive. CHEBI:84183 3-methylundecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84183 CHEBI:84182 2-methylhexadecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84182 GO:0071327 cellular response to trehalose stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071327 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose stimulus. GO:0071326 cellular response to monosaccharide stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071326 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus. CHEBI:84181 12-methyloctadecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84181 GO:0071325 cellular response to mannitol stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071325 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannitol stimulus. CHEBI:84180 10-HPO(6,8,12)TrE biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84180 GO:0071324 cellular response to disaccharide stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071324 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disaccharide stimulus. GO:0071323 cellular response to chitin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071323 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus. GO:0071322 cellular response to carbohydrate stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071322 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus. GO:0071321 cellular response to cGMP biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071321 cellular response to guanosine 3',5'-cyclophosphate|cellular response to 3',5'-cGMP|cellular response to cyclic GMP|cellular response to 3',5' cGMP Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cGMP (cyclic GMP, guanosine 3',5'-cyclophosphate) stimulus. GO:0071320 cellular response to cAMP biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071320 cellular response to 3',5'-cAMP|cellular response to adenosine 3',5'-cyclophosphate|cellular response to cyclic AMP|cellular response to 3',5' cAMP Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus. SO:0001683 sequence_motif biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0001683 http://en.wikipedia.org/wiki/Sequence_motif sequence motif A sequence motif is a nucleotide or amino-acid sequence pattern that may have biological significance. GO:0046374 teichoic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046374 teichoic acid metabolism The chemical reactions and pathways involving teichoic acid, any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues. GO:0046373 L-arabinose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046373 L-arabinose metabolism The chemical reactions and pathways involving L-arabinose, the D-enantiomer of arabino-pentose. L-arabinose occurs free, e.g. in the heartwood of many conifers, and in the combined state, in both furanose and pyranose forms, as a constituent of various plant hemicelluloses, bacterial polysaccharides etc. GO:0046372 D-arabinose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046372 D-arabinose metabolism The chemical reactions and pathways involving D-arabinose, the D-enantiomer of arabino-pentose. D-arabinose occurs in plant glycosides and is a constituent of arabinonucleosides. GO:0046371 dTDP-mannose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046371 dTDP-mannose metabolism The chemical reactions and pathways involving dTDP-mannose, a substance composed of mannose in glycosidic linkage with deoxyribosylthymine diphosphate. GO:0046370 fructose biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046370 fructose biosynthesis|fructose anabolism|fructose synthesis|fructose formation The chemical reactions and pathways resulting in the formation of fructose, the ketohexose arabino-2-hexulose. GO:1900448 obsolete regulation of pyrimidine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900448 OBSOLETE. Any process that modulates the frequency, rate or extent of pyrimidine nucleotide biosynthesis by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:1900447 regulation of cell morphogenesis involved in phenotypic switching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900447 regulation of cell shape and cell size of phenotypic switching|regulation of cell shape and cell size of phenotypic dimorphism|positive regulation of cell shape and cell size of phenotypic dimorphism|regulation of cell morphogenesis of phenotypic dimorphism|negative regulation of cell shape and cell size of phenotypic dimorphism|regulation of cell morphogenesis of phenotypic switching|negative regulation of cell shape and cell size of phenotypic switching|positive regulation of cell shape and cell size of phenotypic switching Any process that modulates the frequency, rate or extent of cell morphogenesis contributing a phenotypic switch. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells, such as the opaque cells of C. albicans, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. CHEBI:25822 p-cumate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_25822 GO:1900449 regulation of glutamate receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900449 regulation of glutamate signaling pathway|regulation of glutamate signalling pathway Any process that modulates the frequency, rate or extent of glutamate receptor signaling pathway. GO:1900444 negative regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900444 down-regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus|downregulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus|down regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus|inhibition of filamentous growth of a population of unicellular organisms in response to biotic stimulus Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus. CL:0002119 CD38-positive IgG-negative class switched memory B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002119 A CD38-positive IgG-negative memory B cell is an IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD38-positive and IgG-negative. PR:000021066 pancreatic prohormone proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000021066 PPY/ClvPrd A pancreatic prohormone that has been processed by proteolytic cleavage. GO:1900443 regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900443 Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus. CL:0002118 CD38-negative IgG-negative class switched memory B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002118 A CD38-negative IgG-negative memory B cell is a IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD38-negative and IgG-negative. GO:1900446 obsolete negative regulation of tRNA transcription from RNA polymerase III promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900446 down-regulation of tRNA transcription from Pol III promoter|negative regulation of tRNA transcription from Pol III promoter|down-regulation of tRNA transcription from RNA polymerase III promoter|inhibition of tRNA transcription from RNA polymerase III promoter|downregulation of tRNA transcription from Pol III promoter|down regulation of tRNA transcription from Pol III promoter|down regulation of tRNA transcription from RNA polymerase III promoter|inhibition of tRNA transcription from Pol III promoter|downregulation of tRNA transcription from RNA polymerase III promoter OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of tRNA transcription from RNA polymerase III promoter. GO:1900445 positive regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900445 upregulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus|up-regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus|activation of filamentous growth of a population of unicellular organisms in response to biotic stimulus|up regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus. GO:0046379 extracellular polysaccharide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046379 extracellular polysaccharide metabolism The chemical reactions and pathways involving polysaccharides used in extracellular structures. GO:0046378 enterobacterial common antigen metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046378 enterobacterial common antigen metabolism The chemical reactions and pathways involving enterobacterial common antigen, an acidic polysaccharide containing N-acetyl-D-glucosamine, N-acetyl-D-mannosaminouronic acid, and 4-acetamido-4,6-dideoxy-D-galactose. A major component of the cell wall outer membrane of Gram-negative bacteria. GO:1900440 regulation of filamentous growth of a population of unicellular organisms in response to neutral pH biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900440 Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to neutral pH. GO:0046377 colanic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046377 colanic acid metabolism The chemical reactions and pathways involving colanic acid, a capsular bacterial polysaccharide composed of glucose, galactose, fucose and glucuronic acid residues. GO:1900442 positive regulation of filamentous growth of a population of unicellular organisms in response to neutral pH biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900442 upregulation of filamentous growth of a population of unicellular organisms in response to neutral pH|up regulation of filamentous growth of a population of unicellular organisms in response to neutral pH|activation of filamentous growth of a population of unicellular organisms in response to neutral pH|up-regulation of filamentous growth of a population of unicellular organisms in response to neutral pH Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to neutral pH. GO:0046376 GDP-alpha-D-mannosylchitobiosyldiphosphodolichol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046376 GDP-alpha-D-mannosylchitobiosyldiphosphodolichol metabolism The chemical reactions and pathways involving GDP-alpha-D-mannosylchitobiosyldiphosphodolichol, a substance composed of mannosylchitobiosyldiphosphodolichol in glycosidic linkage with guanosine diphosphate. GO:0061990 beta-ketodecanoyl-[acyl-carrier-protein] synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061990 RHEA:42264|MetaCyc:RXN-13613 Catalysis of the reaction: octanoyl-CoA + a malonyl-[acyl-carrier protein] = a 3-oxodecanoyl-[acyl-carrier protein] + CoA + CO2. GO:0046375 K antigen metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046375 K antigen metabolism The chemical reactions and pathways involving K antigen, a capsular polysaccharide antigen carried on the surface of bacterial capsules that masks somatic (O) antigens. GO:1900441 negative regulation of filamentous growth of a population of unicellular organisms in response to neutral pH biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900441 down regulation of filamentous growth of a population of unicellular organisms in response to neutral pH|downregulation of filamentous growth of a population of unicellular organisms in response to neutral pH|down-regulation of filamentous growth of a population of unicellular organisms in response to neutral pH|inhibition of filamentous growth of a population of unicellular organisms in response to neutral pH Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to neutral pH. GO:0061993 calcium:proton antiporter complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0061993 IntAct:EBI-2292448|IntAct:EBI-16693477|IntAct:EBI-16710427 CAX1-CAX3 complex|CAX3 homodimer|CAX1 homodimer A protein complex that enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + H+(out) = Ca2+(out) + H+(in). CL:0002111 CD38-negative unswitched memory B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002111 CD38- unswitched memory B-cell|CD38- unswitched memory B-lymphocyte|CD38-negative unswitched memory B lymphocyte|CD38- unswitched memory B cell|CD38- unswitched memory B lymphocyte|CD38-negative unswitched memory B-cell|CD38-negative unswitched memory B-lymphocyte An CD38-negative unswitched memory B cell is an unswitched memory B cell that has the phenotype CD38-negative, IgD-positive, CD138-negative, and IgG-negative. GO:0061992 ATP-dependent chaperone mediated protein folding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061992 The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone, and dependent on ATP hydrolysis. CL:0002110 B220-low CD38-positive naive B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002110 A B220-low CD38-positive naive B cell is a CD38-positive naive B cell that has the phenotype B220-low, CD38-positive, surface IgD-positive, surface IgM-positive, and CD27-negative, that has not yet been activated by antigen in the periphery. GO:0061995 ATP-dependent protein-DNA complex displacement activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061995 Catalysis of the reaction: ATP + H2O = ADP + phosphate coupled to the displacement of proteins or protein complexes from DNA, sometimes in a 'wire stripping' fashion. CL:0002113 B220-low CD38-negative unswitched memory B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002113 A B220-low CD38-negative unswitched memory B cell is a CD38-negative unswitched memory B cell that has the phenotype B220-low, CD38-negative, IgD-positive, CD138-negative, and IgG-negative. CL:0002112 B220-positive CD38-negative unswitched memory B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002112 A B220-positive CD38-negative unswitched memory B cell is a CD38-negative unswitched memory B cell that has the phenotype B220-positive, CD38-negative, IgD-positive, CD138-negative, and IgG-negative. GO:0061994 ATP-dependent protein-nucleic acid complex displacement activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0061994 Catalysis of the reaction: ATP + H2O = ADP + phosphate coupled to the displacement of proteins or protein complexes from nucleic acid, sometimes in a 'wire stripping' fashion. CHEBI:84198 3-hydroxytetradecanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84198 CL:0002115 B220-positive CD38-positive unswitched memory B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002115 A B220-positive CD38-positive unswitched memory B cell is a CD38-positive unswitched memory B cell that has the phenotype B220-positive, CD38-positive, IgD-positive, CD138-negative, and IgG-negative. CHEBI:84197 3-hydroxytetradecanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84197 GO:0071319 cellular response to benzoic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071319 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzoic acid stimulus. CL:0002114 CD38-positive unswitched memory B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002114 CD38-positive unswitched memory B-lymphocyte|CD38+ unswitched memory B-cell|CD38+ unswitched memory B-lymphocyte|CD38-positive unswitched memory B lymphocyte|CD38+ unswitched memory B cell|CD38+ unswitched memory B lymphocyte|CD38-positive unswitched memory B-cell A CD38-positive unswitched memory B cell is an unswitched memory B cell that has the phenotype CD38-positive, IgD-positive, CD138-negative, and IgG-negative. CHEBI:84196 3-hydroxy fatty acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84196 GO:0061999 regulation of cardiac endothelial to mesenchymal transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0061999 Any process that modulates the frequency, rate or extent of cardiac endothelial to mesenchymal transition. CL:0002117 IgG-negative class switched memory B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002117 IgG- class switched memory B cell|IgG- class switched memory B lymphocyte|IgG-negative class switched memory B-cell|IgG-negative class switched memory B-lymphocyte|IgG- class switched memory B-cell|IgG- class switched memory B-lymphocyte|IgG-negative class switched memory B lymphocyte A class switched memory B cell that lacks IgG on the cell surface. GO:0071318 cellular response to ATP biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071318 cellular response to adenosine 5'-triphosphate|cellular response to adenosine triphosphate Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus. CHEBI:84195 isomyristoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84195 GO:0071317 cellular response to isoquinoline alkaloid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071317 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isoquinoline alkaloid stimulus. An isoquinoline alkaloid is any member of a group of compounds with the heterocyclic ring structure of benzo(c)pyridine which is a structure characteristic of the group of opium alkaloids. CL:0002116 B220-low CD38-positive unswitched memory B cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002116 A B220-low CD38-positive unswitched memory B cell is a CD38-positive unswitched memory B cell that has the phenotype B220-low, CD38-positive, IgD-positive, CD138-negative, and IgG-negative. CHEBI:84194 hydroxytryptophan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84194 CHEBI:84193 isomyristate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84193 GO:0071316 cellular response to nicotine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071316 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus. GO:0071315 cellular response to morphine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071315 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a morphine stimulus. Morphine is an opioid alkaloid, isolated from opium, with a complex ring structure. SO:0001679 transcription_regulatory_region biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0001679 transcription regulatory region A regulatory region that is involved in the control of the process of transcription. GO:0071314 cellular response to cocaine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071314 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cocaine stimulus. Cocaine is a crystalline alkaloid obtained from the leaves of the coca plant. CHEBI:25826 p-menthane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_25826 CHEBI:84191 D-glucaro-1,5-lactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84191 GO:0071313 cellular response to caffeine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071313 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them. CHEBI:84190 D-galactaro-1,5-lactone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84190 GO:0071312 cellular response to alkaloid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071312 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active. GO:0071311 cellular response to acetate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071311 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus. GO:0071310 cellular response to organic substance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071310 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus. GO:0071341 medial cortical node biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071341 midsome|mid1p medial cortical dot A component of the cell division site that contains the mid1, cdr2, wee1, klp8, and blt1 proteins, and is involved in contractile ring localization. Medial cortical node complexes appear as cortical dots in the middle of the cell during interphase, and function to recruit other ring components in early mitosis. GO:0046385 deoxyribose phosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046385 deoxyribose phosphate anabolism|deoxyribose phosphate synthesis|deoxyribose phosphate formation|deoxyribose phosphate biosynthesis The chemical reactions and pathways resulting in the formation of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose. GO:0046384 2-deoxyribose 1-phosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046384 2-deoxyribose 1-phosphate metabolism|deoxyribose 1-phosphate metabolic process|deoxyribose 1-phosphate metabolism The chemical reactions and pathways involving 2-deoxyribose 1-phosphate, the phosphorylated sugar 1-phospho-2-deoxyribose. GO:0071340 skeletal muscle acetylcholine-gated channel clustering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071340 skeletal muscle nicotinic acetylcholine receptor clustering|skeletal muscle AChR clustering The accumulation of acetylcholine-gated cation channels in a narrow, central region of muscle fibers, in apposition to nerve terminals. GO:0046383 dTDP-rhamnose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046383 dTDP-rhamnose metabolism The chemical reactions and pathways involving dTDP-rhamnose, a substance composed of rhamnose in glycosidic linkage with deoxyribosylthymine diphosphate. GO:0046382 GDP-D-rhamnose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046382 GDP-D-rhamnose metabolism The chemical reactions and pathways involving GDP-D-rhamnose, a substance composed of rhamnose in glycosidic linkage with guanosine diphosphate. GO:1900459 positive regulation of brassinosteroid mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900459 upregulation of brassinosteroid mediated signalling|upregulation of brassinosteroid mediated signaling pathway|up regulation of brassinosteroid mediated signalling|positive regulation of brassinosteroid mediated signalling|up-regulation of brassinosteroid mediated signaling pathway|activation of brassinosteroid mediated signaling pathway|activation of brassinosteroid mediated signalling|up-regulation of brassinosteroid mediated signalling|up regulation of brassinosteroid mediated signaling pathway Any process that activates or increases the frequency, rate or extent of brassinosteroid mediated signaling pathway. GO:0046381 CMP-N-acetylneuraminate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046381 CMP-N-acetylneuraminate metabolism The chemical reactions and pathways involving CMP-N-acetylneuraminate, a substance composed of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid in glycosidic linkage with cytidine monophosphate. GO:0046380 N-acetylneuraminate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046380 N-acetylneuraminate synthesis|N-acetylneuraminate formation|N-acetylneuraminate biosynthesis|N-acetylneuraminate anabolism The chemical reactions and pathways resulting in the formation of N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid. GO:1900458 negative regulation of brassinosteroid mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900458 down regulation of brassinosteroid mediated signaling pathway|down regulation of brassinosteroid mediated signalling|inhibition of brassinosteroid mediated signaling pathway|downregulation of brassinosteroid mediated signalling|down-regulation of brassinosteroid mediated signalling|negative regulation of brassinosteroid mediated signalling|down-regulation of brassinosteroid mediated signaling pathway|inhibition of brassinosteroid mediated signalling|downregulation of brassinosteroid mediated signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of brassinosteroid mediated signaling pathway. GO:1900455 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1900455 GO:1900454 positive regulation of long-term synaptic depression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900454 up regulation of LTD|positive regulation of LTD|up-regulation of long term synaptic depression|upregulation of long term depression|activation of LTD|positive regulation of long term synaptic depression|up-regulation of LTD|upregulation of long term synaptic depression|up-regulation of long term depression|activation of long term depression|upregulation of LTD|up regulation of long term synaptic depression|positive regulation of long term depression|activation of long term synaptic depression|up regulation of long term depression Any process that activates or increases the frequency, rate or extent of long term synaptic depression. GO:1900457 regulation of brassinosteroid mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900457 regulation of brassinosteroid mediated signalling Any process that modulates the frequency, rate or extent of brassinosteroid mediated signaling pathway. GO:1900456 obsolete regulation of invasive growth in response to glucose limitation by regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900456 regulation of invasive growth in response to glucose limitation by regulation of transcription from RNA polymerase II promoter|regulation of colony morphology by regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that modulates the frequency, rate or extent of invasive growth in response to glucose limitation by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:1900451 positive regulation of glutamate receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900451 up-regulation of glutamate signaling pathway|positive regulation of glutamate signalling pathway|up regulation of glutamate signalling pathway|upregulation of glutamate signaling pathway|up regulation of glutamate receptor signaling pathway|upregulation of glutamate signalling pathway|up regulation of glutamate signaling pathway|positive regulation of glutamate signaling pathway|upregulation of glutamate receptor signaling pathway|up-regulation of glutamate signalling pathway|activation of glutamate signaling pathway|activation of glutamate signalling pathway|up-regulation of glutamate receptor signaling pathway|activation of glutamate receptor signaling pathway Any process that activates or increases the frequency, rate or extent of glutamate receptor signaling pathway. GO:0046389 deoxyribose 5-phosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046389 deoxyribose 5-phosphate metabolism The chemical reactions and pathways involving deoxyribose 5-phosphate, the phosphorylated sugar 5-phospho-2-deoxyribose. GO:1900450 negative regulation of glutamate receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900450 inhibition of glutamate signaling pathway|down-regulation of glutamate receptor signaling pathway|downregulation of glutamate signalling pathway|down regulation of glutamate signalling pathway|down regulation of glutamate signaling pathway|downregulation of glutamate receptor signaling pathway|downregulation of glutamate signaling pathway|inhibition of glutamate signalling pathway|down regulation of glutamate receptor signaling pathway|inhibition of glutamate receptor signaling pathway|down-regulation of glutamate signaling pathway|negative regulation of glutamate signaling pathway|down-regulation of glutamate signalling pathway|negative regulation of glutamate signalling pathway Any process that stops, prevents or reduces the frequency, rate or extent of glutamate receptor signaling pathway. GO:0046388 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046388 GO:1900453 negative regulation of long-term synaptic depression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900453 down-regulation of long term synaptic depression|downregulation of long term depression|down regulation of long term depression|inhibition of long term synaptic depression|negative regulation of LTD|down-regulation of LTD|inhibition of long term depression|down regulation of long term synaptic depression|inhibition of LTD|negative regulation of long term synaptic depression|downregulation of long term synaptic depression|down-regulation of long term depression|negative regulation of long term depression|down regulation of LTD|downregulation of LTD Any process that stops, prevents or reduces the frequency, rate or extent of long term synaptic depression. GO:0046387 deoxyribose 1,5-bisphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046387 deoxyribose 1,5-bisphosphate metabolism The chemical reactions and pathways involving deoxyribose 1,5-bisphosphate, the diphosphorylated sugar 1,5-diphospho-2-deoxyribose. GO:1900452 regulation of long-term synaptic depression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900452 regulation of long term depression|regulation of long term synaptic depression|regulation of LTD Any process that modulates the frequency, rate or extent of long term synaptic depression. GO:0046386 deoxyribose phosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046386 deoxyribose phosphate catabolism|deoxyribose phosphate degradation|deoxyribose phosphate breakdown The chemical reactions and pathways resulting in the breakdown of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose. GO:1900460 obsolete negative regulation of invasive growth in response to glucose limitation by negative regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900460 negative regulation of colony morphology by negative regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of invasive growth in response to glucose limitation by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:0071349 cellular response to interleukin-12 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071349 cellular response to IL-12 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-12 stimulus. GO:0071348 cellular response to interleukin-11 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071348 cellular response to IL-11 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-11 stimulus. GO:0071347 cellular response to interleukin-1 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071347 cellular response to IL-1 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus. GO:0071346 cellular response to interferon-gamma biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071346 cellular response to type II IFN|cellular response to type II interferon|cellular response to immune interferon|cellular response to gamma-interferon Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon gamma is the only member of the type II interferon found so far. GO:0071345 cellular response to cytokine stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071345 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus. GO:0071344 diphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071344 pyrophosphate metabolism The chemical reactions and pathways involving diphosphate, the anion or salt of diphosphoric acid. GO:0071343 obsolete negative regulation of establishment of actomyosin contractile ring localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071343 negative regulation of establishment of contractile ring localisation involved in cell cycle cytokinesis|negative regulation of establishment of contractile ring localization involved in cell cycle cytokinesis|negative regulation of establishment of contractile ring localization involved in cytokinesis during cell cycle|negative regulation of establishment of actomyosin contractile ring localization OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the process in which a contractile ring is assembled in a specific location. GO:0071342 regulation of establishment of actomyosin contractile ring localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071342 regulation of establishment of contractile ring localisation involved in cell cycle cytokinesis|regulation of establishment of contractile ring localization involved in cell cycle cytokinesis|regulation of establishment of contractile ring localization involved in cytokinesis during cell cycle Any process that modulates the frequency, rate or extent of the process in which a contractile ring is assembled in a specific location that contributes to cytokinesis during cell cycle. GO:0046396 D-galacturonate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046396 D-galacturonate metabolism The chemical reactions and pathways involving D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid. D-galacturonic acid is a component of plant gums and bacterial cell walls. GO:0071330 cellular response to trehalose-6-phosphate stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071330 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose-6-phosphate stimulus. GO:0046395 carboxylic acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046395 carboxylic acid degradation|carboxylic acid breakdown|carboxylic acid catabolism The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups. GO:0046394 carboxylic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046394 carboxylic acid synthesis|carboxylic acid formation|carboxylic acid biosynthesis|carboxylic acid anabolism The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups. GO:0046393 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046393 GO:0046392 galactarate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046392 MetaCyc:GALACTARDEG-PWY galactarate catabolism|galactarate degradation|galactarate breakdown|D-galactarate degradation|D-galactarate breakdown|D-galactarate catabolism|D-galactarate catabolic process The chemical reactions and pathways resulting in the breakdown of galactarate, the anion of galactaric acid. GO:1900469 negative regulation of phosphatidylserine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900469 inhibition of phosphatidylserine biosynthetic process|inhibition of phosphatidylserine formation|inhibition of phosphatidylserine biosynthesis|negative regulation of phosphatidylserine anabolism|down-regulation of phosphatidylserine anabolism|negative regulation of phosphatidylserine synthesis|down-regulation of phosphatidylserine synthesis|down regulation of phosphatidylserine biosynthetic process|down regulation of phosphatidylserine biosynthesis|negative regulation of phosphatidylserine formation|down-regulation of phosphatidylserine formation|downregulation of phosphatidylserine anabolism|downregulation of phosphatidylserine biosynthetic process|downregulation of phosphatidylserine biosynthesis|downregulation of phosphatidylserine synthesis|down regulation of phosphatidylserine anabolism|downregulation of phosphatidylserine formation|down regulation of phosphatidylserine synthesis|down-regulation of phosphatidylserine biosynthesis|negative regulation of phosphatidylserine biosynthesis|down-regulation of phosphatidylserine biosynthetic process|inhibition of phosphatidylserine anabolism|down regulation of phosphatidylserine formation|inhibition of phosphatidylserine synthesis Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylserine biosynthetic process. CHEBI:25801 oxoproline biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25801 GO:0046391 5-phosphoribose 1-diphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046391 MetaCyc:PRPP-PWY PRPP metabolic process|5-phosphoribose 1-diphosphate metabolism The chemical reactions and pathways involving 5-phosphoribose 1-diphosphate, also known as 5-phosphoribosyl-1-pyrophosphate. GO:0046390 ribose phosphate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046390 ribose phosphate anabolism|ribose phosphate synthesis|ribose phosphate formation|ribose phosphate biosynthesis The chemical reactions and pathways resulting in the formation of ribose phosphate, any phosphorylated ribose sugar. GO:1900466 obsolete positive regulation of arginine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900466 upregulation of arginine synthesis by positive regulation of transcription from RNA polymerase II promoter|upregulation of arginine formation by positive regulation of transcription from RNA polymerase II promoter|up-regulation of arginine anabolism by positive regulation of transcription from RNA polymerase II promoter|up-regulation of arginine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of arginine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|activation of arginine anabolism by positive regulation of transcription from RNA polymerase II promoter|up-regulation of arginine synthesis by positive regulation of transcription from RNA polymerase II promoter|activation of arginine synthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of arginine formation by positive regulation of transcription from RNA polymerase II promoter|activation of arginine formation by positive regulation of transcription from RNA polymerase II promoter|upregulation of arginine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|upregulation of arginine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|positive regulation of arginine anabolism by positive regulation of transcription from RNA polymerase II promoter|up regulation of arginine anabolism by positive regulation of transcription from RNA polymerase II promoter|positive regulation of arginine synthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of arginine synthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of arginine formation by positive regulation of transcription from RNA polymerase II promoter|up regulation of arginine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of arginine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up regulation of arginine formation by positive regulation of transcription from RNA polymerase II promoter|positive regulation of arginine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|activation of arginine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|activation of arginine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|upregulation of arginine anabolism by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that activates or increases the frequency, rate or extent of arginine biosynthetic process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:1900465 obsolete negative regulation of arginine catabolic process by negative regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900465 negative regulation of arginine degradation by negative regulation of transcription from RNA polymerase II promoter|negative regulation of arginine breakdown by negative regulation of transcription from RNA polymerase II promoter|negative regulation of arginine catabolism by negative regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of cellular arginine catabolic process by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:1900468 regulation of phosphatidylserine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900468 regulation of phosphatidylserine biosynthesis|regulation of phosphatidylserine anabolism|regulation of phosphatidylserine synthesis|regulation of phosphatidylserine formation Any process that modulates the frequency, rate or extent of phosphatidylserine biosynthetic process. GO:1900467 obsolete regulation of cellular potassium ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900467 regulation of cellular potassium ion homeostasis OBSOLETE. Any process that modulates the frequency, rate or extent of cellular potassium ion homeostasis. GO:1900462 obsolete negative regulation of pseudohyphal growth by negative regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900462 OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of pseudohyphal growth by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:1900461 positive regulation of pseudohyphal growth by positive regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900461 Any process that activates or increases the frequency, rate or extent of pseudohyphal growth by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:0046399 glucuronate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046399 glucuronate biosynthesis|glucuronate anabolism|glucuronate synthesis|glucuronate formation The chemical reactions and pathways resulting in the formation of glucuronate, the anion of glucuronic acid. GO:0046398 UDP-glucuronate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046398 UDP-glucuronate metabolism The chemical reactions and pathways involving UDP-glucuronate, a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate. GO:1900464 negative regulation of cellular hyperosmotic salinity response by negative regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900464 negative regulation of cellular response to hyperosmotic salt stress by negative regulation of transcription from RNA polymerase II promoter Any process that stops, prevents, or reduces the frequency, rate or extent of cellular hyperosmotic salinity response by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:0046397 galacturonate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046397 galacturonate degradation|galacturonate catabolism|galacturonate breakdown The chemical reactions and pathways resulting in the breakdown of galacturonate, the anion of galacturonic acid. GO:1900463 negative regulation of cellular response to alkaline pH by negative regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900463 negative regulation of cellular response to basic pH by negative regulation of transcription from RNA polymerase II promoter|negative regulation of cellular response to alkalinity by negative regulation of transcription from RNA polymerase II promoter Any process that stops, prevents, or reduces the frequency, rate or extent of cellular response to alkalinity by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter. UBERON:0002492 sagittal suture biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002492 sagittal suture of skull|sutura sagittalis the dense, fibrous connective tissue joint between the tetrapod parietal bones UBERON:0002491 lambdoid suture biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002491 lambdoidal suture|sutura lambdoidea|lambdoid suture of skull the dense, fibrous connective tissue joint between the parietal bones and the occipital bone GO:1900471 obsolete negative regulation of inositol biosynthetic process by negative regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900471 negative regulation of inositol anabolism by negative regulation of transcription from RNA polymerase II promoter|negative regulation of inositol synthesis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of inositol formation by negative regulation of transcription from RNA polymerase II promoter|negative regulation of inositol biosynthesis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of vitamin Bh biosynthetic process by negative regulation of transcription from RNA polymerase II promoter|negative regulation of vitamin Bh biosynthesis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of myo-inositol biosynthesis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of myo-inositol biosynthetic process by negative regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of inositol biosynthetic process by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:1900470 positive regulation of phosphatidylserine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900470 upregulation of phosphatidylserine anabolism|activation of phosphatidylserine biosynthesis|upregulation of phosphatidylserine synthesis|upregulation of phosphatidylserine formation|up-regulation of phosphatidylserine biosynthesis|up-regulation of phosphatidylserine biosynthetic process|up-regulation of phosphatidylserine anabolism|up-regulation of phosphatidylserine synthesis|activation of phosphatidylserine anabolism|up-regulation of phosphatidylserine formation|upregulation of phosphatidylserine biosynthetic process|upregulation of phosphatidylserine biosynthesis|activation of phosphatidylserine synthesis|positive regulation of phosphatidylserine anabolism|up regulation of phosphatidylserine anabolism|activation of phosphatidylserine formation|positive regulation of phosphatidylserine synthesis|up regulation of phosphatidylserine synthesis|positive regulation of phosphatidylserine formation|up regulation of phosphatidylserine biosynthesis|up regulation of phosphatidylserine biosynthetic process|up regulation of phosphatidylserine formation|positive regulation of phosphatidylserine biosynthesis|activation of phosphatidylserine biosynthetic process Any process that activates or increases the frequency, rate or extent of phosphatidylserine biosynthetic process. UBERON:0002490 frontal suture biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002490 metopic suture|sutura metopica|median frontal suture|frontal suture of skull|sutura frontalis|sutura frontalis A suture that connects the two frontal bones of the skull. GO:0071339 MLL1 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071339 A protein complex that can methylate lysine-4 of histone H3. MLL1/MLL is the catalytic methyltransferase subunit, and the complex also contains the core components ASH2L, HCFC1/HCF1 WDR5 and RBBP5. GO:0071338 positive regulation of hair follicle cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071338 upregulation of hair follicle cell proliferation|stimulation of hair follicle cell proliferation|up-regulation of hair follicle cell proliferation|activation of hair follicle cell proliferation|up regulation of hair follicle cell proliferation Any process that activates or increases the rate or extent of hair follicle cell proliferation. CHEBI:25806 oxygen molecular entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25806 GO:0071337 negative regulation of hair follicle cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071337 inhibition of hair follicle cell proliferation|down-regulation of hair follicle cell proliferation|downregulation of hair follicle cell proliferation|down regulation of hair follicle cell proliferation Any process that stops, prevents or reduces the rate or extent of hair follicle cell proliferation. CHEBI:25805 oxygen atom biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_25805 GO:0071336 regulation of hair follicle cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071336 Any process that modulates the frequency, rate or extent of hair follicle cell proliferation. GO:0071335 hair follicle cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071335 The multiplication or reproduction of hair follicle cells, resulting in the expansion of a cell population. GO:0071334 cellular response to rhamnose stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071334 cellular response to L-rhamnose stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rhamnose stimulus. GO:0071333 cellular response to glucose stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071333 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus. UBERON:0002495 long bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002495 os longum Long bone is a limb bone that is subcylindrical and has a shaft with periosteum separating the ends of the bones. Long bones are present only in the limbs[VSAO:wd]. UBERON:0002498 deltopectoral crest biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002498 crista ventralis humeri|pectoral process|deltoid tuberosity|crista ventralis|deltoid crest|deltoid eminence|tuberositas deltoidea humeri|tuberositas deltoidea|deltoid process|tuberositas deltoidea (corpus humeri)|deltoid impression|deltoid tuberosity of humerus a rough elevation at the middle of the lateral side of the shaft of the humerus to which the deltoid muscle attaches GO:0071332 cellular response to fructose stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071332 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus. CHEBI:25807 organooxygen heterocyclic antibiotic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25807 UBERON:0002497 acromion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002497 acromion of the scapula|scapular acromion|acromion process|acromion of scapula Region of the scapula where the latter meets with the clavicle: attachment point of the clavicle to the scapula in some taxa. GO:0071331 cellular response to hexose stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071331 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus. UBERON:0002519 otolithic part of statoconial membrane biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002519 membrana statoconiorum|otolith layer of statoconial membrane|otolithic membrane The layer of the statoconial membrane that is composed of otoliths CHEBI:50776 3-decaprenyl-4-hydroxy-5-methoxybenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50776 UBERON:0002518 otolith organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002518 otolith organs|saccule and utricle|utricle and saccule the crystalline particles composed of calcium carbonate and a protein which adhere to the gelatinous membrane of the maculae of the utricle and saccule (otolithic membrane) CHEBI:50775 3-decaprenyl-4,5-dihydroxybenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50775 CHEBI:50774 2-decaprenyl-6-methoxyphenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50774 CHEBI:74744 N(6),N(6)-dimethyladenosine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74744 UBERON:0002514 intramembranous bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002514 membrane bone|intramembranous bones Bone tissue forms directly within mesenchyme, and does not replace other tissues[TAO]. Intramembranous ossification is the formation of bone in which osteoblasts secrete a collagen-proteoglycan matrix that binds calcium salts and becomes calcified[GO]. Intramembranous ossification is the way flat bones and the shell of a turtle are formed[GO]. Unlike endochondral ossification, cartilage is not present during intramembranous ossification[WP]. CHEBI:50779 appetite enhancer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50779 UBERON:0002517 basicranium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002517 basis cranii|cranial base|base of cranium|base of skull The base of skull is the most inferior area of the skull, composed of the endocranium and lower parts of the skull roof. CHEBI:74748 2'-O-methylcytidine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74748 CHEBI:60102 sulfurated eukaryotic molybdenum cofactor(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60102 CHEBI:35135 iron-sulfur protein biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35135 CHEBI:35134 metalloprotein biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35134 CHEBI:60101 UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60101 CHEBI:60104 alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60104 CHEBI:35137 hemoprotein biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35137 CHEBI:35136 iron protein biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35136 CHEBI:35139 uronic acid phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35139 CHEBI:60106 streptidine 6-phosphate zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60106 CHEBI:35138 aldotetrose phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35138 CHEBI:60105 alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl(1-) group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60105 CHEBI:60108 3-[(5S,6R)-5,6-dihydroxycyclohexa-1,3-dienyl]acrylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60108 CHEBI:60107 N(5)-[(hydroxyamino)(imino)methyl]-L-ornithinium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60107 UBERON:0002522 tunica media biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002522 tunica media vasorum The middle layer of an artery or vein. [WP,unvetted]. UBERON:0002521 elastic tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002521 elastic connective tissue|elastic fiber|textus connectivus elasticus Connective tissue composed of elastic fibers. CHEBI:60109 3-[(5R,6S)-5,6-dihydroxycyclohexa-1,3-dienyl]acrylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60109 CHEBI:59108 N(4)-glycosylated L-asparagine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59108 UBERON:0002523 tunica intima biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002523 Bichat's tunic|intima|tunica intima vasorum The innermost layer of a blood vessel which is a lining of endothelial cells facing the lumen[Kardong]. CHEBI:59107 EC 3.4.24.* (metalloendopeptidase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59107 CHEBI:35131 aldose phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35131 CHEBI:50770 N,N-dihydroxypentahomomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50770 CHEBI:35133 ketoheptose phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35133 CHEBI:35132 ketose phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35132 CHEBI:50765 N,N-dihydroxyhexahomomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50765 UBERON:0002507 abdominal lymph node biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002507 parietal abdominal lymph node|abdomen lymph node|lymph node of abdomen A lymph node that is part of an abdomen [Automatically generated definition]. CHEBI:50764 N-hydroxyhexahomomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50764 CHEBI:50763 N-hydroxypentahomomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50763 UBERON:0002509 mesenteric lymph node biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002509 mesenteric node|nodi lymphoidei mesenterici The lymph nodes located in the mesentery, of which there are 3 classes: ileocolic, juxtaintestinal mesenteric, and central superior group. CHEBI:50762 N-hydroxytetrahomomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50762 CHEBI:74755 aclacinomycin T(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74755 CHEBI:50769 N,N-dihydroxytetrahomomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50769 CHEBI:50768 N,N-dihydroxytrihomomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50768 UBERON:0002506 iris epithelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002506 epithelial tissue of iris|iris pigmented epithelium|epithelium of iris|epithelium pigmentosum iridis|epithelium pigmentosum (iris)|iris epithelial tissue|pigmented epithelium of iris|iris epithelium An epithelium that is part of a iris [Automatically generated definition]. CHEBI:50767 N,N-dihydroxydihomomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50767 CHEBI:50766 N,N-dihydroxy-alpha-amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50766 CHEBI:49770 methyl red biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49770 CHEBI:60111 N(5)-[amino(hydroxyimino)methyl]-L-ornithine zwitterion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60111 CHEBI:60110 1-(3-sn-phosphatidyl)-sn-glycerol 3-phosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60110 CHEBI:35146 (S)-3-methyl-2-oxovalerate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35146 CHEBI:60113 (R)-nipecotamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60113 CHEBI:35145 D-glucuronic acid 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35145 CHEBI:35148 (6'S)-beta,epsilon-carotene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35148 CHEBI:60115 (S)-nipecotamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60115 CHEBI:60114 alpha,alpha-trehalose-2-sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60114 CHEBI:35147 (6'R)-beta,epsilon-carotene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35147 CHEBI:60117 trehalose sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60117 CHEBI:60116 nipecotamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60116 CHEBI:60119 sphingosine 1-phosphate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60119 CHEBI:60118 (R)-nipecotamide(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60118 UBERON:0002511 trabecula carnea biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002511 trabeculae carneae cordis|ventricle trabecula carnea|heart trabecula|trabecula of heart|ventricular trabecula|columnae carneae|cardiac trabecula|trabeculae carneae the supporting bundles of muscular fibers lining the walls of the ventricles of the heart UBERON:0002513 endochondral bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002513 cartilaginous bone|endochondral bones|ossified chondrogenic bone Replacement bone that forms within cartilage. CHEBI:50761 N-hydroxytrihomomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50761 CHEBI:35142 aldotriose phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35142 CHEBI:11152 1,2-didecanoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_11152 CHEBI:50760 N-hydroxy-alpha-amino-acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50760 CHEBI:74752 thiophosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_74752 CHEBI:35143 hemoglobin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35143 CHEBI:50754 cyclohexanecarboxylate ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50754 CHEBI:25798 oxopentanoates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25798 CHEBI:50753 isoflavonoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50753 CHEBI:74764 Cys-tRNA(Sec) polyanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74764 CHEBI:50751 anti-estrogen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50751 CHEBI:74769 2-methyladenosine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74769 CHEBI:50758 N-hydroxydihomomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50758 CHEBI:25799 oxopentanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25799 GO:0046503 glycerolipid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046503 glycerolipid catabolism|glycerolipid degradation|glycerolipid breakdown The chemical reactions and pathways resulting in the breakdown of glycerolipids, any lipid with a glycerol backbone. GO:0046502 uroporphyrinogen III metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046502 uroporphyrinogen III metabolism The chemical reactions and pathways involving uroporphyrinogen III, a precursor for synthesis of vitamin B12, chlorophyll, and heme in organisms that produce these compounds. GO:0046501 protoporphyrinogen IX metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046501 protoporphyrinogen IX metabolism The chemical reactions and pathways involving protoporphyrinogen IX, the specific substrate for the enzyme ferrochelatase, which catalyzes the insertion of iron to form protoheme. It is probably also the substrate for chlorophyll formation. GO:0046500 S-adenosylmethionine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046500 S-adenosyl methionine metabolic process|S-adenosylmethionine metabolism|SAM metabolic process|S-adenosyl methionine metabolism The chemical reactions and pathways involving S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism. CHEBI:50759 N-formyl amino acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50759 CHEBI:60120 (R)-nipecotic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60120 CHEBI:35113 elemental mercury biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35113 GO:0046509 1,2-diacylglycerol 3-beta-galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046509 EC:2.4.1.46|RHEA:14945|KEGG_REACTION:R02691|MetaCyc:2.4.1.46-RXN UDP-galactose:1,2-diacyl-sn-glycerol 3-beta-D-galactosyltransferase activity|MGDG synthase activity|1-beta-MGDG activity|uridine diphosphogalactose-1,2-diacylglycerol galactosyltransferase activity|UDP galactose-1,2-diacylglycerol galactosyltransferase activity|UDPgalactose:1,2-diacylglycerol 3-beta-D-galactosyltransferase activity|UDP-galactose:diacylglycerol galactosyltransferase activity|1beta-MGDG|monogalactosyldiacylglycerol synthase activity|UDP-galactose-diacylglyceride galactosyltransferase activity Catalysis of the reaction: 1,2-diacyl-sn-glycerol + UDP-D-galactose = 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + H(+) + UDP. CHEBI:35115 elemental manganese biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35115 GO:0046508 hydrolase activity, acting on carbon-sulfur bonds biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046508 EC:3.13.-.- hydrolase activity, acting on carbon-sulphur bonds Catalysis of the hydrolysis of any carbon-sulfur bond, C-S. CHEBI:35114 3-isopropylmalic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35114 GO:0046507 UDPsulfoquinovose synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046507 MetaCyc:RXN-1223|KEGG_REACTION:R05775|RHEA:13197|EC:3.13.1.1 UDPsulphoquinovose synthase activity|UDP-sulfoquinovose synthase activity|UDP-6-sulfo-6-deoxyglucose sulfohydrolase activity|sulfite:UDP-glucose sulfotransferase activity Catalysis of the reaction: sulfite + UDP-D-glucose = H(2)O + UDP-6-sulfoquinovose. GO:0046506 sulfolipid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046506 sulfolipid anabolism|sulfolipid biosynthesis|sulfolipid synthesis|sulfolipid formation|sulpholipid biosynthetic process|sulpholipid biosynthesis The chemical reactions and pathways resulting in the formation of sulfolipid, a compound containing a sulfonic acid residue joined by a carbon-sulfur bond to a lipid. GO:0046505 sulfolipid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046505 sulfolipid metabolism|sulpholipid metabolism|sulpholipid metabolic process The chemical reactions and pathways involving sulfolipids, any compound containing a sulfonic acid residue joined by a carbon-sulfur bond to a lipid. CHEBI:60129 (1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60129 GO:0046504 glycerol ether biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046504 glycerol ether anabolism|glycerol ether synthesis|glycerol ether formation|glycerol ether biosynthesis The chemical reactions and pathways resulting in the formation of glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol. CHEBI:50750 EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50750 CHEBI:74778 N(4)-methylcytidine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74778 CHEBI:74777 N(4)-methylcytidine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74777 CHEBI:50746 N(6)-dihydrolipoyl-L-lysine residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50746 CHEBI:50745 progestogen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50745 GO:0046514 ceramide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046514 ceramide catabolism|ceramide degradation|ceramide breakdown The chemical reactions and pathways resulting in the breakdown of ceramides, any N-acetylated sphingoid. GO:0046513 ceramide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046513 ceramide anabolism|ceramide synthesis|ceramide formation|ceramide biosynthesis The chemical reactions and pathways resulting in the formation of ceramides, any N-acylated sphingoid. GO:0046512 sphingosine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046512 sphingosine biosynthesis|sphingosine anabolism|sphingosine synthesis|sphingosine formation The chemical reactions and pathways resulting in the formation of sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues. CHEBI:50748 antipsoriatic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50748 GO:0046511 sphinganine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046511 sphinganine anabolism|dihydrosphingosine biosynthetic process|dihydrosphingosine biosynthesis|sphinganine synthesis|sphinganine biosynthesis|sphinganine formation The chemical reactions and pathways resulting in the formation of sphinganine, D-erythro-2-amino-1,3-octadecanediol. GO:0046510 UDP-sulfoquinovose:DAG sulfoquinovosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046510 MetaCyc:RXN-1224|RHEA:49468 UDP-sulphoquinovose:DAG sulphoquinovosyltransferase activity|sulfolipid synthase Catalysis of the reaction: UDP-sulfoquinovose + 1,2-diacylglycerol = sulfoquinovosyldiacylglycerol + UDP. CHEBI:60131 (1S,6R)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60131 CHEBI:49751 D-monapterin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49751 GO:0046519 sphingoid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046519 sphingoid base metabolic process|sphingoid metabolism|sphingoid base metabolism The chemical reactions and pathways involving sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds. GO:0046518 octamethylcyclotetrasiloxane metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046518 octamethylcyclotetrasiloxane metabolism The chemical reactions and pathways involving octamethylcyclotetrasiloxane, a cyclic silicone-oxygen ring compound with two methyl groups attached to each silicone atom. CHEBI:35128 (2S)-2-isopropylmalic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35128 GO:0046517 octamethylcyclotetrasiloxane catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046517 octamethylcyclotetrasiloxane degradation|octamethylcyclotetrasiloxane breakdown|octamethylcyclotetrasiloxane catabolism The chemical reactions and pathways resulting in the breakdown of octamethylcyclotetrasiloxane, a cyclic silicone-oxygen ring compound with two methyl groups attached to each silicone atom. GO:0046516 hypusine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046516 hypusine metabolism The chemical reactions and pathways involving hypusine, N6-(4-amino-2-hydroxybutyl)-L-lysine. GO:0046515 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046515 CHEBI:74770 2-methyladenosine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74770 CHEBI:74771 N(3)-methyluridine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74771 CHEBI:11173 1,4-dihydroxy-2-naphthoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_11173 CHEBI:35121 (2R,3S)-3-isopropylmalate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35121 CHEBI:74773 N(3)-methyluridine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74773 CHEBI:74787 8-methyladenosine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74787 CHEBI:74786 N(2),N(2)-dimethylguanosine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74786 CHEBI:74788 8-methyladenosine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74788 UBERON:0002559 medullary reticular formation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002559 reticular formation of medulla|reticular formation of medulla oblongata|medulla oblonmgata reticular formation|reticular formation of metepencephalon|medullary reticular nucleus|bulbar reticular formation|formatio reticularis myelencephali|medulla oblongata reticular formation|rhombencephalic reticular formation|reticular formation|metepencephalon reticular formation|reticular formation of bulb|reticular formation of medulla oblonmgata|bulb reticular formation The reticular formation is a series of brain nuclei located in the medulla oblongata CHEBI:49747 methylmercury(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_49747 UBERON:0002558 organ cavity biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002558 cavity of organ CHEBI:50733 nutraceutical biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50733 GO:0046525 xylosylprotein 4-beta-galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046525 Reactome:R-HSA-1889981|Reactome:R-HSA-3560804|MetaCyc:2.4.1.133-RXN|RHEA:15297|EC:2.4.1.133 uridine diphosphogalactose-xylose galactosyltransferase activity|UDPgalactose:O-beta-D-xylosylprotein 4-beta-D-galactosyltransferase activity|UDP-D-galactose:xylose galactosyltransferase activity|UDP-galactose:xylose galactosyltransferase activity|galactosyltransferase I activity|UDP-D-galactose:D-xylose galactosyltransferase activity|UDP-galactose:O-beta-D-xylosylprotein 4-beta-D-galactosyltransferase activity Catalysis of the reaction: UDP-galactose + O-beta-D-xylosylprotein = UDP + 4-beta-D-galactosyl-O-beta-D-xylosylprotein. GO:0046524 sucrose-phosphate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046524 EC:2.4.1.14|MetaCyc:SUCROSE-PHOSPHATE-SYNTHASE-RXN|RHEA:22172 UDPglucose-fructose-phosphate glucosyltransferase activity|SPS|sucrose phosphate synthetase activity|uridine diphosphoglucose-fructose phosphate glucosyltransferase activity|sucrose 6-phosphate synthase activity|sucrose phosphate-uridine diphosphate glucosyltransferase activity|sucrosephosphate-UDP glucosyltransferase activity|UDP-glucose-fructose-phosphate glucosyltransferase activity|UDPglucose:D-fructose-6-phosphate 2-alpha-D-glucosyltransferase activity|UDP-glucose:D-fructose-6-phosphate 2-alpha-D-glucosyltransferase activity Catalysis of the reaction: UDP-glucose + D-fructose 6-phosphate = UDP + sucrose 6-phosphate. GO:0046523 S-methyl-5-thioribose-1-phosphate isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046523 Reactome:R-HSA-1237096|EC:5.3.1.23|RHEA:19989|KEGG_REACTION:R04420|Reactome:R-HSA-1299507|MetaCyc:5.3.1.23-RXN S-methyl-5-thio-D-ribose-1-phosphate aldose-ketose-isomerase activity|S-methyl-5-thio-5-deoxy-D-ribose-1-phosphate ketol-isomerase activity|5-methylthioribose-1-phosphate isomerase activity|S-methyl-5-thio-alpha-D-ribose-1-phosphate aldose-ketose-isomerase activity|S-methyl-5-thio-5-deoxy-D-ribose-1-phosphate aldose-ketose-isomerase activity|5-methylthio-5-deoxy-D-ribose-1-phosphate ketol-isomerase activity|methylthioribose 1-phosphate isomerase activity|MTR-1-P isomerase activity|1-phospho-5'-S-methylthioribose isomerase activity|1-PMTR isomerase activity Catalysis of the reaction: S-methyl-5-thio-alpha-D-ribose 1-phosphate = S-methyl-5-thio-D-ribulose 1-phosphate. GO:0046522 S-methyl-5-thioribose kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046522 MetaCyc:5-METHYLTHIORIBOSE-KINASE-RXN|RHEA:22312|KEGG_REACTION:R04143|EC:2.7.1.100 5-methylthioribose kinase activity|ATP:S-methyl-5-thio-D-ribose 1-phosphotransferase activity|5-methylthioribose kinase (phosphorylating)|ATP:S5-methyl-5-thio-D-ribose 1-phosphotransferase activity|methylthioribose kinase activity|MTR kinase activity Catalysis of the reaction: S-methyl-5-thio-D-ribose + ATP = S-methyl-5-thio-alpha-D-ribose 1-phosphate + ADP + 2 H(+). CHEBI:84107 1-O-(4-oxoretinoyl)-beta-D-glucuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84107 GO:0046521 sphingoid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046521 sphingoid breakdown|sphingoid catabolism|sphingoid degradation The chemical reactions and pathways resulting in the breakdown of sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds. GO:0046520 sphingoid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046520 sphingoid anabolism|sphingoid synthesis|sphingoid formation|sphingoid biosynthesis The chemical reactions and pathways resulting in the formation of sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds. CHEBI:84105 ketoretinoic acid glucuronide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84105 GO:0046529 imaginal disc fusion, thorax closure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046529 The joining of the parts of the wing imaginal discs, giving rise to the adult thorax. GO:0046528 imaginal disc fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046528 The process following disc eversion whereby imaginal discs fuse with adjacent disc derivatives to form a continuous adult epidermis. GO:0046527 glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046527 Catalysis of the transfer of a glucosyl group to an acceptor molecule, typically another carbohydrate or a lipid. GO:0046526 D-xylulose reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046526 Reactome:R-HSA-5662471|RHEA:20433|KEGG_REACTION:R01896|EC:1.1.1.9|MetaCyc:D-XYLULOSE-REDUCTASE-RXN xylitol dehydrogenase activity Catalysis of the reaction: NAD(+) + xylitol = D-xylulose + H(+) + NADH. CHEBI:74781 5-carboxymethylaminomethyluridine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74781 CHEBI:74783 astringent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74783 UBERON:0002561 lumen of central nervous system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002561 neuraxis lumen|neuraxis cavity|cavity of neuraxis|cavity of ventricular system of neuraxis The cavity that is enclosed by the central nervous system. In vertebrates this is the cavity that includes as parts ventricular cavities and the central canal of the spinal cord that develops from the lumen of the neura tube CHEBI:74782 5-carboxymethylaminomethyluridine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74782 CHEBI:74785 5-carboxymethylaminomethyl-2'-O-methyluridine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74785 CHEBI:74784 5-carboxymethylaminomethyl-2'-O-methyluridine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74784 UBERON:0002548 larva biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002548 veliger|planula|ammocoete|nymph|maggot|naiad|grub|glochidium|leptocephalus|trochophore|zoea|tadpole|caterpillar|wriggler|bipinnaria|larval organism A distinct juvenile form many animals undergo before metamorphosis into adults. Animals with indirect development such as insects, amphibians, or cnidarians typically have a larval phase of their life cycle. CHEBI:50725 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50725 CHEBI:25789 hexenedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25789 CHEBI:50723 (Z)-phenylacetaldehyde oxime biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50723 UBERON:6003006 adult segment biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_6003006 Segment of the adult. GO:0046536 dosage compensation complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0046536 A protein or protein-RNA complex that localizes to one or more of the sex chromosome(s), where it acts to normalize transcription between different sexes. GO:0046535 detection of chemical stimulus involved in sensory perception of umami taste biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046535 umami taste detection|perception of umami taste, sensory transduction of chemical stimulus|perception of umami taste, detection of chemical stimulus|sensory transduction of umami taste|sensory detection of chemical stimulus during perception of umami taste|sensory detection of umami taste|sensory transduction of chemical stimulus during perception of umami taste The series of events required for a umami taste stimulus to be received and converted to a molecular signal. Umami taste is the savory taste of meats and other foods that are rich in glutamates. UBERON:6003005 adult tagma biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_6003005 Any tagma (UBERON:6000002) that is part of some adult (UBERON:6003004). GO:0046534 positive regulation of photoreceptor cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046534 stimulation of photoreceptor cell differentiation|up-regulation of photoreceptor cell differentiation|activation of photoreceptor cell differentiation|up regulation of photoreceptor differentiation|positive regulation of photoreceptor differentiation|activation of photoreceptor differentiation|stimulation of photoreceptor differentiation|up regulation of photoreceptor cell differentiation|up-regulation of photoreceptor differentiation|upregulation of photoreceptor cell differentiation|upregulation of photoreceptor differentiation Any process that activates or increases the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster. CHEBI:60151 oxidised LDL biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60151 CHEBI:50726 CDP-2,3-bis-O-(geranylgeranyl)-sn-glycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50726 CHEBI:84118 ganglioside GM3 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84118 GO:0046533 negative regulation of photoreceptor cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046533 down regulation of photoreceptor differentiation|downregulation of photoreceptor differentiation|down-regulation of photoreceptor cell differentiation|down-regulation of photoreceptor differentiation|negative regulation of photoreceptor differentiation|inhibition of photoreceptor differentiation|downregulation of photoreceptor cell differentiation|down regulation of photoreceptor cell differentiation|inhibition of photoreceptor cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster. GO:0046532 regulation of photoreceptor cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046532 regulation of photoreceptor differentiation Any process that modulates the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster. CHEBI:60152 beta-D-Galp-(1->4)-D-GlcpNAc biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60152 GO:0046531 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046531 UBERON:6003009 adult head segment biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_6003009 Segment of the adult head. CHEBI:25781 hex-2-enedioate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25781 GO:0046530 photoreceptor cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046530 The specialization of organization of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. An example of this process is found in Drosophila melanogaster. UBERON:6003007 insect adult head biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_6003007 Head of the adult organism. CHEBI:84114 D-leucine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84114 CHEBI:84113 D-isoleucine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84113 CHEBI:84111 L-isoleucine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84111 CHEBI:60158 (E)-4,8-dimethyl-1,3,7-nonatriene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60158 CHEBI:35106 nitrogen hydride biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35106 GO:0046539 histamine N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046539 RHEA:19301|MetaCyc:HISTAMINE-N-METHYLTRANSFERASE-RXN|KEGG_REACTION:R02155|EC:2.1.1.8|Reactome:R-HSA-175993 S-adenosylmethionine-histamine N-methyltransferase activity|S-adenosyl-L-methionine:histamine N-tele-methyltransferase activity|imidazolemethyltransferase activity|histamine methyltransferase activity|histamine 1-methyltransferase activity|histamine-methylating enzyme Catalysis of the reaction: S-adenosyl-L-methionine(1+) + histamine = N(tau)-methylhistamine + S-adenosyl-L-homocysteine + H(+). GO:0046538 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046538 PGAM-d|glycerate phosphomutase (diphosphoglycerate cofactor) activity Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D-glycerate; this reaction requires the cofactor 2,3-bisphosphoglycerate. GO:0046537 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046537 PGAM-i Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D glycerate; this reaction does not require the cofactor 2,3-bisphosphoglycerate. CHEBI:35107 azane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35107 UBERON:0002553 anatomical cavity biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002553 cavity Anatomical space which contains portions of one or more body substances and is bounded by the internal surface of one maximally connected anatomical structure. Examples: cranial cavity, pharyngeal recess space, nasal cavity, tooth socket, cavity of serous sac, lumen of stomach, lumen of artery, fornix of vagina. CHEBI:50710 dihomomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50710 CHEBI:25754 oxo carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25754 CHEBI:25753 oxo-5beta-cholanic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25753 UBERON:0002537 hermaphrodite gonad biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002537 glandula hermaphroditica|hermaphrodite genitalia|hermaphrodite gland|ovotestis A gonad with both testicular and ovarian aspects[WP]. CHEBI:50714 hexahomomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50714 CHEBI:50713 pentahomomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50713 UBERON:0002536 arthropod sensillum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002536 sensillum Sense organ embedded in the integument and consisting of one or a cluster of sensory neurons and associated sensory structures, support cells and glial cells forming a single organised unit with a largely bona-fide boundary.[FBbt] CHEBI:50712 tetrahomomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50712 UBERON:0002539 pharyngeal arch biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002539 pharyngeal arches|arcus pharyngei|visceral arch|branchial arch One of a series of paired bulges that develop along the lateral walls of the foregut. The pharyngeal arches have developmental contributions from endoderm, mesoderm, and neural crest cells and are separated by anterior lateral endoderm out-pockets known as pharyngeal pouches. UBERON:0002538 hatching gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002538 hgg|frontal gland The cells of the hatching gland contain enzymes responsible for solubilization of the egg chorion, facilitating the hatching process[GO]. A transversely oriented set of cells located deep to the EVL on the pericardial membrane, especially prominent during pharyngula period because of the brightly refractile cytoplasmic granules (containing hatching enzymes) of the principal cells of the gland. CHEBI:50711 trihomomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50711 GO:0046547 trans-aconitate 3-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046547 KEGG_REACTION:R05764|RHEA:22200|MetaCyc:2.1.1.145-RXN|EC:2.1.1.145 S-adenosyl-L-methionine:(E)-prop-1-ene-1,2,3-tricarboxylate 3'-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine(1+) + trans-aconitate = (E)-2-(methoxycarbonylmethyl)but-2-enedioate + S-adenosyl-L-homocysteine. CHEBI:60160 polyester polymer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60160 GO:0046546 development of primary male sexual characteristics biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046546 The process whose specific outcome is the progression of the primary male sexual characteristics over time, from their formation to the mature structures. The primary male sexual characteristics are the testes, and they develop in response to sex hormone secretion. GO:0046545 development of primary female sexual characteristics biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046545 The process whose specific outcome is the progression of the primary female sexual characteristics over time, from their formation to the mature structure. The primary female sexual characteristics are the ovaries, and they develop in response to sex hormone secretion. GO:0046544 development of secondary male sexual characteristics biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046544 The process whose specific outcome is the progression of the secondary male sexual characteristics over time, from their formation to the mature structures. In male humans, these include growth of axillary, chest, and pubic hair, voice changes, and testicular/penile enlargement. Development occurs in response to sex hormone secretion. CHEBI:84129 L-valine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84129 CHEBI:50715 methylnaphthalene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50715 GO:0046543 development of secondary female sexual characteristics biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046543 The process whose specific outcome is the progression of the secondary female sexual characteristics over time, from their formation to the mature structures. In female humans, these include growth of axillary and pubic hair, breast development and menstrual periods. Their development occurs in response to sex hormone secretion. CHEBI:84128 2-carboxyacyl CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84128 CHEBI:25750 oxime biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_25750 CHEBI:60164 ionic polymer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60164 GO:0046542 obsolete alpha-factor export biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046542 alpha-factor export OBSOLETE. The directed movement of alpha-factor, one of the two yeast mating factors, out of a cell. CHEBI:84127 2-carboxyacyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84127 GO:0046541 saliva secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046541 Wikipedia:Salivation salivation The regulated release of saliva from the salivary glands. In man, the saliva is a turbid and slightly viscous fluid, generally of an alkaline reaction, and is secreted by the parotid, submaxillary, and sublingual glands. In the mouth the saliva is mixed with the secretion from the buccal glands. In man and many animals, saliva is an important digestive fluid on account of the presence of the peculiar enzyme, ptyalin. GO:0046540 U4/U6 x U5 tri-snRNP complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0046540 U4/U6.U5 snRNP complex A ribonucleoprotein complex that is formed by the association of the U4/U6 and U5 snRNPs. CHEBI:84124 D-tyrosine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84124 CHEBI:84123 advanced glycation end-product biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84123 GO:0071509 activation of MAPKK activity involved in conjugation with cellular fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071509 activation of MAP kinase kinase activity during conjugation with cellular fusion|conjugation with cellular fusion, activation of MAPKK activity|conjugation with cellular fusion, activation of MAP kinase kinase activity|activation of MAPKK activity involved in mating response Any process that initiates the activity of the inactive enzyme MAP kinase kinase in the context of conjugation with cellular fusion. CHEBI:84122 D-methionine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84122 GO:0071508 activation of MAPK activity involved in conjugation with cellular fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071508 activation of MAPK activity involved in mating response|conjugation with cellular fusion, activation of MAPK activity Any process that initiates the activity of the inactive enzyme MAP kinase in the context of conjugation with cellular fusion. CHEBI:84121 L-methionine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84121 CHEBI:60169 phosphatidylinositol trisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60169 GO:0071507 pheromone response MAPK cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071507 MAPK signaling in response to pheromone|MAPKKK cascade involved in conjugation with cellular fusion|conjugation with cellular fusion, MAPKKK cascade|MAPKKK cascade involved in mating response|Fus3 signaling cascade|MAPK cascade involved in conjugation with cellular fusion|pheromone MAPK module A MAPK cascade that is part of a pheromone response ending in conjugation with cellular fusion. GO:0071506 cellular response to mycophenolic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071506 cellular response to mycophenolate Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycophenolic acid stimulus. GO:0046549 retinal cone cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046549 Development of a cone cell, one of the sensory cells in the eye that reacts to the presence of light. Cone cells contain the photopigment iodopsin or cyanopsin and are responsible for photopic (daylight) vision. GO:0071505 response to mycophenolic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071505 response to mycophenolate Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycophenolic acid stimulus. GO:0046548 retinal rod cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046548 Development of a rod cell, one of the sensory cells in the eye that reacts to the presence of light. Rod cells contain the photopigment rhodopsin or porphyropsin and are responsible for vision in dim light. GO:0071504 cellular response to heparin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071504 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heparin stimulus. UBERON:0002544 digit biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002544 digit (phalangeal portion) plus soft tissue|limb digit|acropodial unit A subdivision of the autopod that has as part a series of phalanges together with associated vasculature, musculature, integument and nerves. It is continuous with the metapodial subdivision of the autopod, but does not include the metapodials. In species such as humans, fully formed digits are distinct, whereas in other species the digits may be connected by interdigital webbing, or may be completely unseparated (for example, in cetaceans). GO:0071503 response to heparin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071503 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heparin stimulus. GO:0071502 cellular response to temperature stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071502 cellular response to thermal stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus. UBERON:0002546 cranial placode biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002546 ectodermal cranial placode|placode|ectodermal placode|cranial placodes Ectodermal placode that develops in the head into a part of the sensory nervous system. With a few exceptions (lens, adenohypophyseal), cranial placodes are neurogenic. GO:0071501 cellular response to sterol depletion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071501 cellular sterol depletion response Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating deprivation of sterols. Sterols are a group of steroids characterized by the presence of one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. GO:0071500 cellular response to nitrosative stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071500 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions. UBERON:0002540 lateral line system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002540 lateral line organs|lateral line stitches|ll|lateral-line organs A line of sensory organs and associated structures along the sides of fish and amphibia that detect vibrations and pressure changes. UBERON:0002541 germ ring biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002541 The thickend rim of the blastoderm evident during late blastula and gastrula stages[FishBase]. Embryonic structure which is a uniform thickened annulus at the blastoderm margin, consisting of two layers in addition to the EVL, the epiblast and the hypoblast. The germ ring is formed by the involution of the blastoderm back upon itself[ZFA] GO:0046550 (3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine biosynthetic process from asparagine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046550 RESID:AA0328 (3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine anabolism from asparagine|(3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine synthesis from asparagine|(3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine formation from asparagine The modification of asparagine to (3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine as found in microcin C7 produced from the mccA gene in E. coli plasmid pMccC7. UBERON:0002529 limb segment biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002529 segment of limb|region of limb|subdivision of limb|limb region|extremity part|free limb segment A major subdivision of a mature or developing limb, including both skeletal elements (or the mesenchyme that gives rise to the skeletal elements) and associated tissues, such as muscle, connective tissue, integument. Examples: autopod region, zeugopod region, stylopod region, metapodial region, arm region. Excludes the limb girdles. CHEBI:50703 8-(methylsulfanyl)octanal oxime biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50703 CHEBI:49713 lithium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49713 CHEBI:50702 7-(methylsulfanyl)heptanal oxime biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50702 CHEBI:50701 6-(methylsulfanyl)hexanal oxime biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50701 UBERON:0002527 pancreatic lymph node biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002527 pyloric lymph node|aJCC level 19 node|pancreas lymph node|lymph node of pancreas|pancreatic node A lymph node that is part of a pancreas [Automatically generated definition]. CHEBI:50700 5-(methylsulfanyl)pentanal oxime biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50700 GO:0046558 arabinan endo-1,5-alpha-L-arabinosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046558 MetaCyc:3.2.1.99-RXN|EC:3.2.1.99 endo-1,5-alpha-L-arabinanase activity|endo-alpha-1,5-arabanase activity|endo-arabanase activity|1,5-alpha-L-arabinan 1,5-alpha-L-arabinanohydrolase activity Catalysis of the endohydrolysis of (1->5)-alpha-arabinofuranosidic linkages in (1->5) arabinans. CHEBI:50707 homomethionine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50707 GO:0046557 glucan endo-1,6-beta-glucosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046557 MetaCyc:3.2.1.75-RXN|EC:3.2.1.75 beta-1,6-glucan 6-glucanohydrolase activity|beta-1->6-glucan hydrolase activity|1,6-beta-D-glucan glucanohydrolase activity|endo-(1->6)-beta-D-glucanase activity|endo-1,6-beta-D-glucanase activity|endo-(1,6)-beta-D-glucanase activity|endo-beta-1,6-glucanase activity|beta-1,6-glucanase-pustulanase activity|endo-1,6-beta-glucanase activity|beta-1,6-glucanase activity|beta-1,6-glucan hydrolase activity Catalysis of the random hydrolysis of (1->6) linkages in (1->6)-beta-D-glucans. GO:0046556 alpha-L-arabinofuranosidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046556 EC:3.2.1.55|MetaCyc:3.2.1.55-RXN alpha-L-arabinosidase activity|alpha-arabinofuranosidase activity|alpha-arabinosidase activity|alpha-N-arabinofuranosidase activity|polysaccharide alpha-L-arabinofuranosidase activity|alpha-L-arabinofuranoside hydrolase activity|arabinofuranosidase activity|L-arabinosidase activity|arabinosidase activity|alpha-L-arabinanase activity|alpha-L-arabinofuranoside arabinofuranohydrolase activity Catalysis of the hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides. CHEBI:60173 purine deoxyribonucleoside biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60173 GO:0046555 acetylxylan esterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046555 MetaCyc:3.1.1.72-RXN|EC:3.1.1.72 Catalysis of the deacetylation of xylans and xylo-oligosaccharides. CHEBI:50704 9-(methylsulfanyl)nonanal oxime biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50704 CHEBI:84139 myo-inositol phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84139 GO:0046554 malate dehydrogenase (NADP+) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046554 RHEA:10824|EC:1.1.1.82|KEGG_REACTION:R00343|MetaCyc:MALATE-DEHYDROGENASE-NADP+-RXN malate NADP dehydrogenase activity|NADP-malate dehydrogenase activity|(S)-malate:NADP+ oxidoreductase activity|NADP-linked malate dehydrogenase activity|malic dehydrogenase (nicotinamide adenine dinucleotide phosphate)|NADP malate dehydrogenase activity Catalysis of the reaction: (S)-malate + NADP+ = oxaloacetate + NADPH + H+. CHEBI:60175 5-hydroxylysine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60175 CHEBI:60174 rhamnogalacturonan I biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60174 CHEBI:84138 (3R)-3,6-diammoniohexanoate(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84138 GO:0046553 D-malate dehydrogenase (decarboxylating) activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046553 KEGG_REACTION:R00215|EC:1.1.1.83|RHEA:18365|MetaCyc:1.1.1.83-RXN D-malate dehydrogenase activity|D-malic enzyme|(R)-malate:NAD+ oxidoreductase (decarboxylating)|bifunctional L(+)-tartrate dehydrogenase-D(+)-malate (decarboxylating) Catalysis of the reaction: (R)-malate + NAD(+) = CO(2) + NADH + pyruvate. GO:0046552 photoreceptor cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046552 The process in which the developmental fate of a cell becomes restricted such that it will develop into a photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments. GO:0046551 retinal cone cell fate commitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046551 The process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell. A retinal cone cell is one of the two photoreceptor subtypes in a camera-type eye. CHEBI:84135 L-serine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84135 CHEBI:84133 D-serine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84133 GO:0046559 alpha-glucuronidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046559 RHEA:20005|MetaCyc:3.2.1.139-RXN|EC:3.2.1.139 alpha-glucosiduronase activity|alpha-D-glucosiduronate glucuronohydrolase activity Catalysis of the reaction: an alpha-D-glucuronoside + H2O = an alcohol + D-glucuronate. UBERON:0002533 post-anal tail bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002533 end bud|tail bud mesenchyme|tailbud|tail bud The rapidly proliferating mass of cells at the caudal extremity of the embryo; remnant of the primitive node. UBERON:0002532 epiblast (generic) biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002532 epiblast|ectoblast|epiblastus|blastocyst|primitive ectoderm In amniote animal embryology, the epiblast is a tissue type derived either from the inner cell mass in mammals or the blastodisc in birds and reptiles. It lies above the hypoblast. In mammalian embryogenesis, the columnar cells of the epiblast are adjacent to the trophoblast, while the cuboidal cells of the hypoblast are closer to the blastocoele. The epiblast, whilst referred to as the primary ectoderm, differentiates to form all three layers of the trilaminar germ disc in a process called gastrulation[WP]. The outer of the two layers of the blastoderm that form during gastrulation, corresponding to primitive ectoderm during gastrulation and to the definitive ectoderm after gastrulation[ZFA] UBERON:0002534 paired fin biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002534 pelvic/pectoral fin|artioptérygie@fr|nageoire paire@fr Fin that is one of a pair located ventrally on the organism. UBERON:0002531 paired fin bud biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002531 fin bud|fin buds An outgrowth on the lateral trunk of the embryo that develops into a paired fin. The fin bud is divided into ectoderm and mesenchyme[cjm, modified from MP]. UBERON:0002530 gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002530 glandula|glandular organ|Druese an organ that functions as a secretory or excretory organ CHEBI:59193 2-iminio-3-(indol-3-yl)propanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59193 CHEBI:59174 hapten biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59174 NCBITaxon:117565 Myxini organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_117565 fish|Hyperotreti|Agnatha|fishes CHEBI:142439 alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_142439 CHEBI:59163 biomarker biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59163 CHEBI:35193 tetraterpene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35193 CHEBI:35192 sesterterpene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35192 CHEBI:35195 surfactant biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35195 CHEBI:35194 isoprene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35194 CHEBI:35196 nitrogen oxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35196 CHEBI:528881 (9Z,12Z,15Z)-octadeca-9,12,15-trienoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_528881 CHEBI:142422 gamma-carboxy-L-glutamate(3-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_142422 NCBITaxon:117569 Hyperoartia organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_117569 fishes|Monorhina|fish|Cephalaspidomorphi|Agnatha NCBITaxon:117571 Euteleostomi organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_117571 Osteichthyes|bony vertebrates NCBITaxon:117570 Teleostomi organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_117570 CHEBI:142410 guanosine 3'-diphosphate 5'-triphosphate hexaanion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142410 CHEBI:35179 2-oxo monocarboxylic acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35179 CHEBI:59140 precorrin carboxylic acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59140 CHEBI:35171 elemental vanadium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35171 CHEBI:35173 2-dehydro-3-deoxy-L-arabinonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35173 CHEBI:35172 vanadium cation biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35172 CHEBI:35175 sulfate salt biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35175 CHEBI:35177 2-oxohexanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35177 CHEBI:35191 triterpene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35191 CHEBI:35190 diterpene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35190 CHEBI:142409 S-alkyl-L-cysteine S-oxide zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142409 CHEBI:35189 sesquiterpene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35189 CHEBI:142408 arylkylammonium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142408 CHEBI:59132 antigen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59132 CHEBI:35181 4-amino-4-deoxychorismate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35181 CHEBI:35184 gluconic acid phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35184 CHEBI:59139 gibberellin carboxylic acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59139 CHEBI:35186 terpene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35186 CHEBI:59138 (8S)-cinchonan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59138 CHEBI:59137 (8xi)-cinchonan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59137 CHEBI:35188 hemiterpene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35188 CHEBI:35187 monoterpene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35187 CHEBI:74721 N(2)-methylguanosine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74721 CHEBI:74720 N(7)-methylguanosine 5'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74720 CHEBI:74722 N(2)-methylguanosine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74722 CHEBI:74725 5-methylcytidine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74725 CHEBI:74724 5-methylcytidine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74724 CHEBI:35157 aldoheptose phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35157 CHEBI:35159 ribose monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35159 CHEBI:35158 ribose bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35158 CHEBI:50793 2-methyl-3-oxosuccinic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50793 CHEBI:35155 elemental calcium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35155 CHEBI:50787 L-erythro-3-methylmalic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50787 CHEBI:74731 N(3)-methylpseudouridine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74731 CHEBI:50786 anabolic androgenic steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50786 CHEBI:74736 N(1)-methyladenosine 5'-monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74736 CHEBI:74735 N(1)-methyladenosine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74735 CHEBI:50789 (3S)-3-hydroxy-L-asparagine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50789 CHEBI:35168 hydrogenvanadate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35168 CHEBI:35169 dihydrogenvanadate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35169 CHEBI:35160 phosphomethylribose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35160 CHEBI:35162 acyclic carotene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35162 CHEBI:35161 deoxyketopentose phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35161 CHEBI:50783 ent-isokaurene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_50783 CHEBI:35164 2,4'-dihydroxyacetophenone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35164 CHEBI:35163 cyclic carotene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35163 CHEBI:35166 vanadium coordination entity biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35166 CHEBI:50781 EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50781 CHEBI:74730 N(3)-methylpseudouridine 5'-monophosphate residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_74730 CHEBI:50780 appetite regulator biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_50780 GO:0071484 cellular response to light intensity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071484 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light intensity stimulus. GO:0071483 cellular response to blue light biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071483 cellular response to blue light stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a blue light stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm. GO:0071482 cellular response to light stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071482 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light. GO:0071481 cellular response to X-ray biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071481 cellular response to X-ray radiation stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz). GO:0071480 cellular response to gamma radiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071480 cellular response to gamma ray|cellular response to gamma-ray photon Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum. GO:1900359 positive regulation of nigerotriose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900359 up regulation of nigerotriose transport|upregulation of nigerotriose transport|up-regulation of nigerotriose transport|activation of nigerotriose transport Any process that activates or increases the frequency, rate or extent of nigerotriose transport. GO:1900356 positive regulation of methanofuran metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900356 upregulation of methanofuran metabolic process|up-regulation of methanofuran metabolism|up-regulation of methanofuran metabolic process|activation of methanofuran metabolic process|upregulation of methanofuran metabolism|up regulation of methanofuran metabolism|positive regulation of methanofuran metabolism|up regulation of methanofuran metabolic process|activation of methanofuran metabolism Any process that activates or increases the frequency, rate or extent of methanofuran metabolic process. GO:1900355 negative regulation of methanofuran metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900355 inhibition of methanofuran metabolic process|inhibition of methanofuran metabolism|down regulation of methanofuran metabolism|down-regulation of methanofuran metabolic process|downregulation of methanofuran metabolism|downregulation of methanofuran metabolic process|down-regulation of methanofuran metabolism|negative regulation of methanofuran metabolism|down regulation of methanofuran metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of methanofuran metabolic process. GO:1900358 negative regulation of nigerotriose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900358 downregulation of nigerotriose transport|down regulation of nigerotriose transport|inhibition of nigerotriose transport|down-regulation of nigerotriose transport Any process that stops, prevents or reduces the frequency, rate or extent of nigerotriose transport. GO:1900357 regulation of nigerotriose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900357 Any process that modulates the frequency, rate or extent of nigerotriose transport. GO:1900352 negative regulation of methanofuran biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900352 inhibition of methanofuran biosynthesis|down regulation of methanofuran biosynthetic process|down regulation of methanofuran biosynthesis|downregulation of methanofuran biosynthetic process|downregulation of methanofuran biosynthesis|down-regulation of methanofuran biosynthesis|negative regulation of methanofuran biosynthesis|down-regulation of methanofuran biosynthetic process|inhibition of methanofuran biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of methanofuran biosynthetic process. GO:1900351 regulation of methanofuran biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900351 regulation of methanofuran biosynthesis Any process that modulates the frequency, rate or extent of methanofuran biosynthetic process. GO:1900354 regulation of methanofuran metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900354 regulation of methanofuran metabolism Any process that modulates the frequency, rate or extent of methanofuran metabolic process. GO:1900353 positive regulation of methanofuran biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900353 up-regulation of methanofuran biosynthetic process|up-regulation of methanofuran biosynthesis|upregulation of methanofuran biosynthesis|upregulation of methanofuran biosynthetic process|up regulation of methanofuran biosynthesis|up regulation of methanofuran biosynthetic process|activation of methanofuran biosynthetic process|positive regulation of methanofuran biosynthesis|activation of methanofuran biosynthesis Any process that activates or increases the frequency, rate or extent of methanofuran biosynthetic process. GO:1900361 negative regulation of pentasaccharide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900361 downregulation of pentasaccharide transport|down-regulation of pentasaccharide transport|inhibition of pentasaccharide transport|down regulation of pentasaccharide transport Any process that stops, prevents or reduces the frequency, rate or extent of pentasaccharide transport. GO:1900360 regulation of pentasaccharide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900360 Any process that modulates the frequency, rate or extent of pentasaccharide transport. GO:0071489 cellular response to red or far red light biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071489 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red or far red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs. GO:0071488 cellular response to very low light intensity stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071488 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low light intensity stimulus. A very low light intensity stimulus is defined as a level of electromagnetic radiation below 0.001 mmol/m2/sec. GO:0071487 cellular response to low light intensity stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071487 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low light intensity stimulus. Low light intensity is defined as a level of electromagnetic radiation at or below 0.1 micromols/m2. GO:0071486 cellular response to high light intensity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071486 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus. GO:0071485 cellular response to absence of light biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071485 cellular response to darkness Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an absence of light stimuli. GO:0071473 cellular response to cation stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071473 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cation stress, an increase or decrease in the concentration of positively charged ions in the environment. GO:0071472 cellular response to salt stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071472 cellular response to ionic osmotic stress|cellular salinity response Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. GO:0071471 cellular response to non-ionic osmotic stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071471 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of non-ionic solutes (e.g. mannitol, sorbitol) in the environment. GO:0071470 cellular response to osmotic stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071470 cellular osmotic stress response|cellular osmotic response Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. GO:1900367 positive regulation of defense response to insect biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900367 upregulation of defense response to insect|positive regulation of physiological defense response to insect|up regulation of physiological defense response to insect|up-regulation of defense response to insect|activation of defense response to insect|upregulation of physiological defense response to insect|up regulation of defense response to insect|up-regulation of physiological defense response to insect|activation of physiological defense response to insect Any process that activates or increases the frequency, rate or extent of defense response to insect. GO:1900366 negative regulation of defense response to insect biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900366 negative regulation of physiological defense response to insect|down-regulation of physiological defense response to insect|susceptibility to insect|downregulation of physiological defense response to insect|down regulation of physiological defense response to insect|inhibition of physiological defense response to insect|down-regulation of defense response to insect|downregulation of defense response to insect|down regulation of defense response to insect|inhibition of defense response to insect Any process that stops, prevents or reduces the frequency, rate or extent of defense response to insect. GO:1900369 negative regulation of RNA interference biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900369 downregulation of posttranscriptional gene silencing by siRNA|down-regulation of RNA interference|downregulation of RNAi|down regulation of RNAi|down-regulation of posttranscriptional gene silencing by siRNA|negative regulation of posttranscriptional gene silencing by siRNA|downregulation of RNA interference|down regulation of RNA interference|inhibition of RNAi|inhibition of RNA interference|inhibition of posttranscriptional gene silencing by siRNA|negative regulation of RNAi|down-regulation of RNAi|down regulation of posttranscriptional gene silencing by siRNA Any process that stops, prevents or reduces the frequency, rate or extent of RNA interference. GO:1900368 regulation of RNA interference biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900368 regulation of posttranscriptional gene silencing by siRNA|regulation of RNAi Any process that modulates the frequency, rate or extent of RNA interference. GO:1900363 regulation of mRNA polyadenylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900363 regulation of cleavage and polyadenylylation specificity factor activity|regulation of mRNA polyadenylylation Any process that modulates the frequency, rate or extent of mRNA polyadenylation. GO:1900362 positive regulation of pentasaccharide transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900362 up regulation of pentasaccharide transport|activation of pentasaccharide transport|up-regulation of pentasaccharide transport|upregulation of pentasaccharide transport Any process that activates or increases the frequency, rate or extent of pentasaccharide transport. GO:1900365 positive regulation of mRNA polyadenylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900365 up regulation of mRNA polyadenylation|positive regulation of cleavage and polyadenylylation specificity factor activity|up regulation of cleavage and polyadenylylation specificity factor activity|up-regulation of mRNA polyadenylylation|activation of mRNA polyadenylylation|upregulation of mRNA polyadenylation|upregulation of cleavage and polyadenylylation specificity factor activity|positive regulation of mRNA polyadenylylation|activation of mRNA polyadenylation|up regulation of mRNA polyadenylylation|up-regulation of mRNA polyadenylation|up-regulation of cleavage and polyadenylylation specificity factor activity|upregulation of mRNA polyadenylylation|activation of cleavage and polyadenylylation specificity factor activity Any process that activates or increases the frequency, rate or extent of mRNA polyadenylation. GO:1900364 negative regulation of mRNA polyadenylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900364 down-regulation of cleavage and polyadenylylation specificity factor activity|negative regulation of cleavage and polyadenylylation specificity factor activity|downregulation of mRNA polyadenylation|down regulation of mRNA polyadenylation|downregulation of cleavage and polyadenylylation specificity factor activity|inhibition of mRNA polyadenylation|down regulation of cleavage and polyadenylylation specificity factor activity|negative regulation of mRNA polyadenylylation|down-regulation of mRNA polyadenylylation|inhibition of cleavage and polyadenylylation specificity factor activity|downregulation of mRNA polyadenylylation|down regulation of mRNA polyadenylylation|down-regulation of mRNA polyadenylation|inhibition of mRNA polyadenylylation Any process that stops, prevents or reduces the frequency, rate or extent of mRNA polyadenylation. GO:1900370 positive regulation of RNA interference biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900370 activation of RNAi|up-regulation of RNA interference|upregulation of posttranscriptional gene silencing by siRNA|activation of RNA interference|positive regulation of RNAi|up regulation of RNAi|up regulation of posttranscriptional gene silencing by siRNA|positive regulation of posttranscriptional gene silencing by siRNA|up regulation of RNA interference|upregulation of RNAi|activation of posttranscriptional gene silencing by siRNA|up-regulation of posttranscriptional gene silencing by siRNA|upregulation of RNA interference|up-regulation of RNAi Any process that activates or increases the frequency, rate or extent of RNA interference. GO:1900372 negative regulation of purine nucleotide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900372 inhibition of purine nucleotide synthesis|downregulation of purine nucleotide biosynthetic process|down regulation of purine nucleotide anabolism|inhibition of purine nucleotide formation|downregulation of purine nucleotide biosynthesis|downregulation of purine nucleotide anabolism|down regulation of purine nucleotide biosynthesis|down regulation of purine nucleotide synthesis|down regulation of purine nucleotide biosynthetic process|inhibition of purine nucleotide biosynthetic process|down regulation of purine nucleotide formation|downregulation of purine nucleotide synthesis|inhibition of purine nucleotide biosynthesis|downregulation of purine nucleotide formation|negative regulation of purine nucleotide anabolism|down-regulation of purine nucleotide anabolism|negative regulation of purine nucleotide synthesis|down-regulation of purine nucleotide synthesis|negative regulation of purine nucleotide formation|down-regulation of purine nucleotide formation|negative regulation of purine nucleotide biosynthesis|down-regulation of purine nucleotide biosynthesis|down-regulation of purine nucleotide biosynthetic process|inhibition of purine nucleotide anabolism Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide biosynthetic processes. GO:1900371 regulation of purine nucleotide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900371 regulation of purine nucleotide biosynthesis|regulation of purine nucleotide anabolism|regulation of purine nucleotide synthesis|regulation of purine nucleotide formation Any process that modulates the frequency, rate or extent of purine nucleotide biosynthetic processes. GO:0071479 cellular response to ionizing radiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071479 cellular response to ionising radiation|cellular response to ionizing radiation stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays. GO:0071478 cellular response to radiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071478 cellular response to electromagnetic radiation stimulus|cellular response to radiation stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation. GO:0071477 cellular hypotonic salinity response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071477 cellular response to hypotonic salt stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. GO:0071476 cellular hypotonic response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071476 cellular hypo-osmotic response Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hypotonic environment, i.e. an environment with a lower concentration of solutes than the organism or cell. GO:0071475 cellular hyperosmotic salinity response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071475 cellular response to hyperosmotic salt stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. GO:0071474 cellular hyperosmotic response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071474 cellular hypertonic response|cellular response to hypertonicity|cellular HOG response Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell. GO:1900378 positive regulation of secondary metabolite biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900378 up regulation of secondary metabolite biosynthesis|up regulation of secondary metabolite biosynthetic process|activation of secondary metabolite biosynthetic process|positive regulation of secondary metabolite biosynthesis|activation of secondary metabolite biosynthesis|up-regulation of secondary metabolite biosynthetic process|up-regulation of secondary metabolite biosynthesis|upregulation of secondary metabolite biosynthetic process|upregulation of secondary metabolite biosynthesis Any process that activates or increases the frequency, rate or extent of secondary metabolite biosynthetic process. GO:1900377 negative regulation of secondary metabolite biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900377 downregulation of secondary metabolite biosynthesis|downregulation of secondary metabolite biosynthetic process|down-regulation of secondary metabolite biosynthetic process|down-regulation of secondary metabolite biosynthesis|negative regulation of secondary metabolite biosynthesis|inhibition of secondary metabolite biosynthetic process|inhibition of secondary metabolite biosynthesis|down regulation of secondary metabolite biosynthesis|down regulation of secondary metabolite biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of secondary metabolite biosynthetic process. GO:1900379 regulation of asperthecin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900379 regulation of asperthecin synthesis|regulation of asperthecin formation|regulation of asperthecin biosynthesis Any process that modulates the frequency, rate or extent of asperthecin biosynthetic process. GO:1900374 obsolete positive regulation of mating type switching by regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900374 upregulation of mating type switching by regulation of transcription from RNA polymerase II promoter|stimulation of mating type switching by regulation of transcription from RNA polymerase II promoter|up-regulation of mating type switching by regulation of transcription from RNA polymerase II promoter|activation of mating type switching by regulation of transcription from RNA polymerase II promoter|up regulation of mating type switching by regulation of transcription from RNA polymerase II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in positive regulation of mating type switching. GO:1900373 positive regulation of purine nucleotide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900373 up-regulation of purine nucleotide formation|positive regulation of purine nucleotide biosynthesis|up regulation of purine nucleotide biosynthetic process|upregulation of purine nucleotide anabolism|up regulation of purine nucleotide biosynthesis|upregulation of purine nucleotide synthesis|upregulation of purine nucleotide formation|up regulation of purine nucleotide anabolism|upregulation of purine nucleotide biosynthetic process|upregulation of purine nucleotide biosynthesis|positive regulation of purine nucleotide anabolism|up regulation of purine nucleotide synthesis|positive regulation of purine nucleotide synthesis|up regulation of purine nucleotide formation|activation of purine nucleotide anabolism|activation of purine nucleotide biosynthetic process|up-regulation of purine nucleotide biosynthesis|up-regulation of purine nucleotide biosynthetic process|positive regulation of purine nucleotide formation|activation of purine nucleotide synthesis|up-regulation of purine nucleotide anabolism|activation of purine nucleotide formation|activation of purine nucleotide biosynthesis|up-regulation of purine nucleotide synthesis Any process that activates or increases the frequency, rate or extent of purine nucleotide biosynthetic processes. GO:1900376 regulation of secondary metabolite biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900376 regulation of secondary metabolite biosynthesis Any process that modulates the frequency, rate or extent of secondary metabolite biosynthetic process. GO:1900375 obsolete positive regulation of inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900375 activation of inositol formation by positive regulation of transcription from RNA polymerase II promoter|up regulation of inositol anabolism by positive regulation of transcription from RNA polymerase II promoter|positive regulation of inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of vitamin Bh biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of vitamin Bh biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up regulation of myo-inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|positive regulation of inositol synthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of myo-inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of vitamin Bh biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|positive regulation of vitamin Bh biosynthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of myo-inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of inositol synthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of myo-inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|activation of inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of inositol formation by positive regulation of transcription from RNA polymerase II promoter|up regulation of inositol formation by positive regulation of transcription from RNA polymerase II promoter|activation of vitamin Bh biosynthesis by positive regulation of transcription from RNA polymerase II promoter|activation of vitamin Bh biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|activation of myo-inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|activation of myo-inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|upregulation of inositol anabolism by positive regulation of transcription from RNA polymerase II promoter|up-regulation of inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up-regulation of inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of vitamin Bh biosynthesis by positive regulation of transcription from RNA polymerase II promoter|upregulation of inositol synthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of vitamin Bh biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up-regulation of myo-inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of myo-inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|upregulation of inositol formation by positive regulation of transcription from RNA polymerase II promoter|up-regulation of inositol anabolism by positive regulation of transcription from RNA polymerase II promoter|upregulation of inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|upregulation of inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of inositol synthesis by positive regulation of transcription from RNA polymerase II promoter|upregulation of vitamin Bh biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|upregulation of vitamin Bh biosynthesis by positive regulation of transcription from RNA polymerase II promoter|upregulation of myo-inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|upregulation of myo-inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|activation of inositol anabolism by positive regulation of transcription from RNA polymerase II promoter|up-regulation of inositol formation by positive regulation of transcription from RNA polymerase II promoter|activation of inositol synthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of inositol anabolism by positive regulation of transcription from RNA polymerase II promoter|up regulation of inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|activation of inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of inositol biosynthetic process. GO:1900381 positive regulation of asperthecin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900381 activation of asperthecin formation|up-regulation of asperthecin synthesis|up-regulation of asperthecin biosynthesis|up-regulation of asperthecin biosynthetic process|activation of asperthecin biosynthetic process|up-regulation of asperthecin formation|activation of asperthecin biosynthesis|upregulation of asperthecin synthesis|upregulation of asperthecin formation|positive regulation of asperthecin biosynthesis|up regulation of asperthecin biosynthesis|up regulation of asperthecin biosynthetic process|up regulation of asperthecin synthesis|positive regulation of asperthecin synthesis|up regulation of asperthecin formation|positive regulation of asperthecin formation|upregulation of asperthecin biosynthetic process|upregulation of asperthecin biosynthesis|activation of asperthecin synthesis Any process that activates or increases the frequency, rate or extent of asperthecin biosynthetic process. GO:1900380 negative regulation of asperthecin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900380 down-regulation of asperthecin formation|negative regulation of asperthecin formation|inhibition of asperthecin biosynthesis|inhibition of asperthecin synthesis|inhibition of asperthecin formation|negative regulation of asperthecin biosynthesis|down-regulation of asperthecin biosynthesis|down-regulation of asperthecin biosynthetic process|down regulation of asperthecin synthesis|down regulation of asperthecin formation|downregulation of asperthecin synthesis|downregulation of asperthecin biosynthetic process|downregulation of asperthecin biosynthesis|downregulation of asperthecin formation|down regulation of asperthecin biosynthetic process|down regulation of asperthecin biosynthesis|inhibition of asperthecin biosynthetic process|down-regulation of asperthecin synthesis|negative regulation of asperthecin synthesis Any process that stops, prevents or reduces the frequency, rate or extent of asperthecin biosynthetic process. GO:1900383 regulation of synaptic plasticity by receptor localization to synapse biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900383 regulation of synaptic plasticity by receptor localisation to synapse Any process that modulates synaptic plasticity, the ability of synapses to change as circumstances require, via receptor localization to the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. Processes may include receptor transport to, and/or maintenance at, the synapse. GO:1900382 obsolete regulation of thiamine biosynthetic process by regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900382 regulation of thiamine anabolism by regulation of transcription from RNA polymerase II promoter|regulation of thiamin biosynthetic process by regulation of transcription from RNA polymerase II promoter|regulation of thiamine biosynthesis by regulation of transcription from RNA polymerase II promoter|regulation of thiamine formation by regulation of transcription from RNA polymerase II promoter|regulation of thiamine synthesis by regulation of transcription from RNA polymerase II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of thiamine biosynthetic process. GO:0071495 cellular response to endogenous stimulus biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0071495 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism. GO:0071494 cellular response to UV-C biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071494 cellular response to UV-C radiation stimulus|cellular response to germicidal ultraviolet light stimulus|cellular response to shortwave ultraviolet light stimulus|cellular response to UVC light stimulus|cellular response to germicidal ultraviolet radiation stimulus|cellular response to shortwave ultraviolet radiation stimulus|cellular response to UVC radiation stimulus|cellular response to UV-C light stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm. GO:0071493 cellular response to UV-B biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071493 cellular response to UV-B radiation stimulus|cellular response to medium wave ultraviolet radiation stimulus|cellular response to UVB light stimulus|cellular response to UVB radiation stimulus|cellular response to UV-B light stimulus|cellular response to medium wave ultraviolet light stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm. GO:0071492 cellular response to UV-A biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071492 cellular response to UV-A radiation stimulus|cellular response to UVA light stimulus|cellular response to UVA radiation stimulus|cellular response to UV-A light stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm. GO:0071491 cellular response to red light biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071491 cellular response to red light stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs. GO:0071490 cellular response to far red light biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071490 cellular response to far red light stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of far red light stimulus. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs. GO:1900389 obsolete regulation of glucose import by regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900389 regulation of glucose uptake by regulation of transcription from RNA polymerase II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of glucose import. CHEBI:225237 2-phenylethanaminium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_225237 GO:1900388 obsolete regulation of vesicle-mediated transport by regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900388 regulation of vesicle-mediated transport by regulation of transcription from RNA polymerase II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of vesicle-mediated transport. CHEBI:225238 benzylaminium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_225238 GO:1900385 negative regulation of flavonol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900385 down-regulation of flavonol biosynthetic process|inhibition of flavonol biosynthetic process|down regulation of flavonol biosynthetic process|downregulation of flavonol biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of flavonol biosynthetic process. GO:1900384 regulation of flavonol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900384 Any process that modulates the frequency, rate or extent of flavonol biosynthetic process. GO:1900387 obsolete negative regulation of cell-cell adhesion by negative regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900387 OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of cell-cell adhesion. GO:1900386 positive regulation of flavonol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900386 up-regulation of flavonol biosynthetic process|upregulation of flavonol biosynthetic process|up regulation of flavonol biosynthetic process|activation of flavonol biosynthetic process Any process that activates or increases the frequency, rate or extent of flavonol biosynthetic process. GO:1900392 obsolete regulation of transport by negative regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900392 OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in regulation of transport. GO:1900391 obsolete regulation of cAMP-mediated signaling by regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900391 regulation of cAMP-mediated signalling by regulation of transcription from RNA polymerase II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of cAMP-mediated signaling. GO:1900394 regulation of kojic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900394 regulation of C6H6O4 formation|regulation of kojic acid synthesis|regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|regulation of kojic acid formation|regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|regulation of kojic acid biosynthesis|regulation of C6H6O4 biosynthetic process|regulation of C6H6O4 biosynthesis|regulation of C6H6O4 anabolism|regulation of C6H6O4 synthesis|regulation of kojic acid anabolism Any process that modulates the frequency, rate or extent of kojic acid biosynthetic process. GO:1900393 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1900393 GO:1900390 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1900390 GO:0071499 cellular response to laminar fluid shear stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071499 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a laminar fluid shear stress stimulus. Laminar fluid flow is the force acting on an object in a system where the fluid is moving across a solid surface in parallel layers. GO:0071498 cellular response to fluid shear stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071498 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface. GO:0071497 cellular response to freezing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071497 ice nucleation inhibitor activity|antifreeze activity Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a freezing stimulus, temperatures below 0 degrees Celsius. GO:0071496 cellular response to external stimulus biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0071496 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus. CHEBI:142493 (3S,4R,5R,6S)-1,3,4,5,6-pentachlorocyclohexene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142493 GO:1900399 positive regulation of pyrimidine nucleotide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900399 up-regulation of pyrimidine nucleotide synthesis|up-regulation of pyrimidine nucleotide formation|upregulation of pyrimidine nucleotide biosynthetic process|upregulation of pyrimidine nucleotide biosynthesis|upregulation of pyrimidine nucleotide anabolism|upregulation of pyrimidine nucleotide synthesis|upregulation of pyrimidine nucleotide formation|up-regulation of pyrimidine nucleotide biosynthetic process|activation of pyrimidine nucleotide biosynthetic process|up-regulation of pyrimidine nucleotide biosynthesis|up regulation of pyrimidine nucleotide anabolism|positive regulation of pyrimidine nucleotide anabolism|up regulation of pyrimidine nucleotide synthesis|activation of pyrimidine nucleotide biosynthesis|positive regulation of pyrimidine nucleotide synthesis|up regulation of pyrimidine nucleotide formation|activation of pyrimidine nucleotide anabolism|positive regulation of pyrimidine nucleotide formation|positive regulation of pyrimidine nucleotide biosynthesis|activation of pyrimidine nucleotide synthesis|up regulation of pyrimidine nucleotide biosynthesis|up regulation of pyrimidine nucleotide biosynthetic process|up-regulation of pyrimidine nucleotide anabolism|activation of pyrimidine nucleotide formation Any process that activates or increases the frequency, rate or extent of pyrimidine nucleotide biosynthetic process. GO:1900396 positive regulation of kojic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900396 up regulation of kojic acid formation|upregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|positive regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|upregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|up regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|upregulation of C6H6O4 synthesis|positive regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|upregulation of kojic acid anabolism|activation of C6H6O4 biosynthetic process|activation of C6H6O4 biosynthesis|up regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|upregulation of kojic acid biosynthesis|upregulation of kojic acid biosynthetic process|upregulation of C6H6O4 formation|upregulation of kojic acid synthesis|up-regulation of C6H6O4 anabolism|upregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|up regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|up-regulation of C6H6O4 biosynthetic process|up-regulation of C6H6O4 biosynthesis|upregulation of kojic acid formation|up regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|up-regulation of kojic acid anabolism|up-regulation of C6H6O4 synthesis|positive regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|upregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|positive regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|activation of C6H6O4 anabolism|up regulation of kojic acid biosynthetic process|up-regulation of C6H6O4 formation|upregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|up regulation of kojic acid biosynthesis|up-regulation of kojic acid synthesis|positive regulation of kojic acid biosynthesis|activation of kojic acid biosynthetic process|activation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|up-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|activation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|activation of kojic acid anabolism|activation of C6H6O4 synthesis|up-regulation of kojic acid formation|positive regulation of C6H6O4 anabolism|upregulation of C6H6O4 biosynthesis|upregulation of C6H6O4 biosynthetic process|up regulation of C6H6O4 anabolism|up-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|activation of C6H6O4 formation|activation of kojic acid biosynthesis|activation of kojic acid synthesis|up-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|positive regulation of kojic acid anabolism|up-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|positive regulation of C6H6O4 synthesis|activation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|up-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|up regulation of C6H6O4 synthesis|up regulation of kojic acid anabolism|activation of kojic acid formation|positive regulation of C6H6O4 formation|positive regulation of kojic acid synthesis|activation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|up regulation of C6H6O4 formation|up-regulation of kojic acid biosynthesis|positive regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|up-regulation of kojic acid biosynthetic process|up regulation of C6H6O4 biosynthesis|up regulation of kojic acid synthesis|up regulation of C6H6O4 biosynthetic process|up regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|positive regulation of kojic acid formation|activation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|upregulation of C6H6O4 anabolism|positive regulation of C6H6O4 biosynthesis|positive regulation of C6H6O4 biosynthetic process Any process that activates or increases the frequency, rate or extent of kojic acid biosynthetic process. GO:1900395 negative regulation of kojic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900395 downregulation of kojic acid synthesis|down regulation of kojic acid anabolism|down regulation of C6H6O4 synthesis|downregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|inhibition of kojic acid biosynthesis|inhibition of C6H6O4 anabolism|down-regulation of C6H6O4 biosynthesis|down-regulation of C6H6O4 biosynthetic process|negative regulation of C6H6O4 biosynthesis|down regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|downregulation of kojic acid formation|down regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|down regulation of C6H6O4 formation|negative regulation of C6H6O4 biosynthetic process|down regulation of kojic acid synthesis|downregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|down regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|downregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|inhibition of C6H6O4 synthesis|inhibition of kojic acid anabolism|downregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|down regulation of kojic acid formation|down regulation of kojic acid biosynthetic process|downregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|down regulation of kojic acid biosynthesis|down regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|inhibition of C6H6O4 formation|inhibition of kojic acid synthesis|inhibition of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|downregulation of kojic acid biosynthetic process|down regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|downregulation of kojic acid biosynthesis|inhibition of kojic acid formation|inhibition of C6H6O4 biosynthetic process|down-regulation of C6H6O4 anabolism|inhibition of C6H6O4 biosynthesis|negative regulation of C6H6O4 anabolism|inhibition of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|negative regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|down-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|negative regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|down-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|down-regulation of C6H6O4 synthesis|inhibition of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|negative regulation of C6H6O4 synthesis|negative regulation of kojic acid anabolism|down-regulation of kojic acid anabolism|down-regulation of kojic acid biosynthetic process|down-regulation of kojic acid biosynthesis|negative regulation of kojic acid biosynthesis|down-regulation of C6H6O4 formation|down regulation of C6H6O4 biosynthesis|negative regulation of C6H6O4 formation|down regulation of C6H6O4 biosynthetic process|down-regulation of kojic acid synthesis|negative regulation of kojic acid synthesis|downregulation of C6H6O4 anabolism|negative regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|down-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|downregulation of C6H6O4 biosynthetic process|downregulation of C6H6O4 biosynthesis|negative regulation of kojic acid formation|down-regulation of kojic acid formation|inhibition of kojic acid biosynthetic process|inhibition of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|inhibition of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|downregulation of kojic acid anabolism|downregulation of C6H6O4 synthesis|down-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|down regulation of C6H6O4 anabolism|negative regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|downregulation of C6H6O4 formation|negative regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|down-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation Any process that stops, prevents or reduces the frequency, rate or extent of kojic acid biosynthetic process. GO:1900398 negative regulation of pyrimidine nucleotide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900398 inhibition of pyrimidine nucleotide anabolism|down regulation of pyrimidine nucleotide biosynthesis|down regulation of pyrimidine nucleotide biosynthetic process|inhibition of pyrimidine nucleotide biosynthetic process|inhibition of pyrimidine nucleotide synthesis|down regulation of pyrimidine nucleotide anabolism|inhibition of pyrimidine nucleotide formation|inhibition of pyrimidine nucleotide biosynthesis|down regulation of pyrimidine nucleotide synthesis|downregulation of pyrimidine nucleotide anabolism|down regulation of pyrimidine nucleotide formation|downregulation of pyrimidine nucleotide synthesis|downregulation of pyrimidine nucleotide formation|down-regulation of pyrimidine nucleotide anabolism|negative regulation of pyrimidine nucleotide anabolism|negative regulation of pyrimidine nucleotide biosynthesis|down-regulation of pyrimidine nucleotide biosynthetic process|down-regulation of pyrimidine nucleotide biosynthesis|down-regulation of pyrimidine nucleotide synthesis|negative regulation of pyrimidine nucleotide synthesis|down-regulation of pyrimidine nucleotide formation|negative regulation of pyrimidine nucleotide formation|downregulation of pyrimidine nucleotide biosynthesis|downregulation of pyrimidine nucleotide biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of pyrimidine nucleotide biosynthetic process. GO:1900397 regulation of pyrimidine nucleotide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900397 regulation of pyrimidine nucleotide biosynthesis|regulation of pyrimidine nucleotide anabolism|regulation of pyrimidine nucleotide synthesis|regulation of pyrimidine nucleotide formation Any process that modulates the frequency, rate or extent of pyrimidine nucleotide biosynthetic process. OIO:SynonymTypeProperty synonym_type_property biolink:OntologyClass go-plus http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty CHEBI:59087 N-{alpha-Man-(1->3)-[alpha-Man-(1->3)-[alpha-Man-(1->6)]-alpha-Man-(1->6)]-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-GlcNac}-L-Asn residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59087 CHEBI:59082 N-{alpha-Glc-(1->3)-alpha-Glc-(1->3)-alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-Man-(1->3)-[alpha-Man-(1->2)-alpha-Man-(1->3)-[alpha-Man-(1->2)-alpha-Man-(1->6)]-alpha-Man-(1->6)]-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-GlcNAc}-L-Asn residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59082 CHEBI:59080 N-{alpha-Glc-(1->3)-alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-Man-(1->3)-[alpha-Man-(1->2)-alpha-Man-(1->3)-[alpha-Man-(1->2)-alpha-Man-(1->6)]-alpha-Man-(1->6)]-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-GlcNAc}-L-Asn residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59080 GO:0046440 L-lysine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046440 L-lysine metabolism The chemical reactions and pathways involving L-lysine, the L-enantiomer of (S)-2,6-diaminohexanoic acid, i.e. (2S)-2,6-diaminohexanoic acid. CHEBI:49703 latrunculin B biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49703 CHEBI:60061 cobalt-precorrin-4(7-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60061 GO:0046448 tropane alkaloid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046448 tropane alkaloid metabolism The chemical reactions and pathways involving tropane alkaloids, compounds containing the 8-methyl-8-azabicyclo(3.2.1)octane ring system. CHEBI:60060 cobalt-precorrin-3(8-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60060 GO:0046447 terpenoid indole alkaloid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046447 terpenoid indole alkaloid metabolism The chemical reactions and pathways involving terpenoid indole alkaloids, compounds formed from the condensation of tryptamine (derived from tryptophan) and secologanin (derived from geranyl pyrophosphate). GO:0046446 purine alkaloid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046446 purine alkaloid metabolism The chemical reactions and pathways involving purine alkaloids, compounds derived from purine and composed of an N-containing double ring structure. CHEBI:60063 cobalt-precorrin-5B(8-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60063 GO:0046445 benzyl isoquinoline alkaloid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046445 benzyl isoquinoline alkaloid metabolism The chemical reactions and pathways involving benzyl isoquinoline alkaloids, compounds with bicyclic N-containing aromatic rings. CHEBI:60062 cobalt-precorrin-5A(7-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60062 GO:0046444 FMN metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046444 FMN metabolism The chemical reactions and pathways involving FMN, riboflavin 5'-(dihydrogen phosphate), a coenzyme for a number of oxidative enzymes including NADH dehydrogenase. CHEBI:84029 (5Z,8Z,11Z)-14,15-dihydroxyicosatrienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84029 CHEBI:60065 alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphingosine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60065 CHEBI:84028 12,13-DiHOME(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84028 GO:0046443 FAD metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046443 oxidized flavin adenine dinucleotide metabolic process|oxidized flavin adenine dinucleotide metabolism|oxidized flavin-adenine dinucleotide metabolism|oxidized flavin-adenine dinucleotide metabolic process|FAD metabolism The chemical reactions and pathways involving FAD, the oxidized form of flavin adenine dinucleotide. CHEBI:60064 cobalt-precorrin-6A(7-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60064 CHEBI:84027 9,10-DiHOME(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84027 GO:0046442 aerobactin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046442 aerobactin metabolism The chemical reactions and pathways involving aerobactin (C22H36N4O13), a hydroxamate iron transport compound. It is a conjugate of 6-(N-acetyl-N-hydroxylamine)-2-aminohexanoic acid and citric acid. CHEBI:84026 vernolate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84026 GO:0046441 D-lysine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046441 D-lysine metabolism The chemical reactions and pathways involving D-lysine, the D-enantiomer of lysine; i.e. (2R)-2,6-diaminohexanoic acid. CHEBI:84025 8,9-EET(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84025 CHEBI:84024 14,15-EET(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84024 CL:0002022 Ly-76 high positive erythrocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002022 An enucleate erythrocyte that is Lyg-76-high. CHEBI:84023 9(10)-EpOME(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84023 GO:0071409 cellular response to cycloheximide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071409 cellular response to actidione Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloheximide stimulus. Cycloheximide (actidione) is an antibiotic produced by some Streptomyces species which interferes with protein synthesis in eukaryotes. CL:0002024 Kit-positive megakaryocyte progenitor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002024 A megakaryocyte progenitor cell that is Kit-positive, CD41-positive, CD9-positive, Sca-1-negative, IL7ralpha-negative, CD150-negative, and Fcgamma receptor II/III-low. GO:0071408 cellular response to cycloalkane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071408 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloalkane stimulus. A cycloalkane is a cyclic saturated hydrocarbon having the general formula CnH2n. CL:0002027 CD9-positive, CD41-positive megakaryocyte cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002027 A megakaryocyte cell with is CD9-positive and CD41-positive. GO:0071407 cellular response to organic cyclic compound biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071407 cellular response to organic cyclic substance Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus. GO:0071406 cellular response to methylmercury biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071406 cellular response to MeHg+|cellular response to CH3-Hg+ Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylmercury stimulus. CL:0002029 Fc-epsilon RIalpha-low mast cell progenitor biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002029 A lineage-negative, Kit-positive, CD45-positive mast cell progenitor that is Fc-epsilon RIalpha-low. CL:0002028 basophil mast progenitor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002028 BMCP A cell type that can give rise to basophil and mast cells. This cell is CD34-positive, CD117-positive, CD125-positive, FceRIa-negative, and T1/ST2-negative, and expresses Gata-1, Gata-2, C/EBPa GO:0071405 cellular response to methanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071405 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methanol stimulus. GO:0046449 creatinine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046449 creatinine metabolism The chemical reactions and pathways involving creatinine, 2-amino-1,5-dihydro-1-methyl-4H-imidazol-4-one, an end product of creatine metabolism and a normal constituent of urine. GO:0071404 cellular response to low-density lipoprotein particle stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071404 response to low density lipoprotein particle|response to low-density lipoprotein particle stimulus|response to low-density lipoprotein particle Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low-density lipoprotein particle stimulus. GO:0071403 cellular response to high density lipoprotein particle stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071403 response to high density lipoprotein particle stimulus|response to high density lipoprotein particle|cellular response to high-density lipoprotein particle stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high density lipoprotein particle stimulus. GO:0071402 cellular response to lipoprotein particle stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071402 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus. CHEBI:49709 chlorate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_49709 GO:0071401 cellular response to triglyceride biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071401 cellular response to triacylglyceride|cellular response to triacylglycerol Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triglyceride stimulus. GO:0071400 cellular response to oleic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071400 cellular response to oleate Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oleic acid stimulus. CL:0002021 GlyA-positive erythrocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002021 An enucleate erythrocyte that is GlyA-positive. CL:0002020 GlyA-positive reticulocytes biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002020 A reticulocyte that is GlyA-positive. GO:0046451 diaminopimelate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046451 diaminopimelate metabolism The chemical reactions and pathways involving diaminopimelate, the anion of the dicarboxylic acid 2,6-diaminoheptanedioic acid. It is an intermediate in lysine biosynthesis and as a component (as meso-diaminopimelate) of the peptidoglycan of Gram-negative bacterial cell walls. GO:0046450 dethiobiotin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046450 desthiobiotin metabolic process|dethiobiotin metabolism|desthiobiotin metabolism The chemical reactions and pathways involving dethiobiotin, a derivative of biotin formed by replacing the sulfur atom by two hydrogen atoms. CHEBI:25741 oxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25741 CHEBI:25747 oxidized luciferins biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25747 GO:0046459 short-chain fatty acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046459 short-chain fatty acid metabolism The chemical reactions and pathways involving fatty acids with a chain length of less than C6. GO:0046458 hexadecanal metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046458 hexadecanal metabolism The chemical reactions and pathways involving hexadecanal, the C16 straight chain aldehyde. GO:0046457 prostanoid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046457 Wikipedia:Prostanoid#Biosynthesis prostanoid anabolism|prostanoid synthesis|prostanoid formation|prostanoid biosynthesis The chemical reactions and pathways resulting in the formation of prostanoids, any compound based on or derived from the prostanoate structure. GO:0046456 icosanoid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046456 Wikipedia:Eicosanoid icosanoid anabolism|icosanoid synthesis|eicosanoid biosynthetic process|eicosanoid biosynthesis|icosanoid formation|icosanoid biosynthesis The chemical reactions and pathways resulting in the formation of icosanoids, any of a group of C20 polyunsaturated fatty acids. CHEBI:60073 N-acylneuraminate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60073 GO:0046455 organosilicon catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046455 organosilicon catabolism|organosilicone catabolism|organosilicon degradation|organosilicon breakdown|organosilicone catabolic process The chemical reactions and pathways resulting in the breakdown of organosilicons, any organic compound that contains silicon. CHEBI:60076 6-O-sinapoyl-D-glucono-1,5-lactone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60076 GO:0046454 dimethylsilanediol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046454 dimethylsilanediol metabolism The chemical reactions and pathways involving dimethylsilanediol, the smallest member of the dialkylsilanediols. Dimethylsilanediol is the monomer of polydimethylsiloxane, a compound which can be found in a wide range of industrial and consumer products. CHEBI:60078 4-O-feruloyl-D-quinate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60078 GO:0046453 dipyrrin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046453 dipyrrin metabolism The chemical reactions and pathways involving dipyrrins (pyrromethanes), compounds containing two pyrrole rings linked through a methine, -CH=, group. CHEBI:60077 luteolin-7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide] biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60077 GO:0046452 dihydrofolate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046452 dihydrofolate reduction|dihydrofolate metabolism The chemical reactions and pathways involving dihydrofolate, the dihydroxylated derivative of folate. CL:0002034 long term hematopoietic stem cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002034 LT-HSC|LT stem cell A hematopoietic stem cell with long term self renewal capability. This cell is Kit-positive, Sca1-positive, CD150-positive, CD90-low, CD34-negative and Flt3-negative. CL:0002033 short term hematopoietic stem cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002033 ST stem cell|ST-HSC A hematopoietic stem cell capable of rapid replenishment of myeloerythroid progenitors and limited self renewal capability. This cell is Kit-positive, Sca1-positive, CD34-positive, CD150-positive, and is Flt3-negative. CHEBI:60079 alpha-N-acetylneuraminyl-(2->6)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60079 CL:0002036 Slamf1-positive multipotent progenitor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002036 KSL cell A hematopoietic progenitor that has some limited self-renewal capability. Cells are lin-negative, Kit-positive, CD34-positive, and Slamf1-positive. CL:0002035 Slamf1-negative multipotent progenitor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002035 A hematopoietic progenitor that has restricted self-renewal capability. Cell is Kit-positive, Ly6-positive, CD150-negative and Flt3-negative. CL:0002038 T follicular helper cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002038 follicular T cell|Tfh|T(FH)|follicular helper T-cell|follicular T-cell|follicular B helper T cell|follicular helper T cell|follicular T-helper cell A CD4-positive, CXCR5-positive, CCR7-negative alpha-beta T cell located in follicles of secondary lymph nodes that expresses is BCL6-high, ICOS-high and PD1-high, and stimulates follicular B cells to undergo class-switching and antibody production. CHEBI:84032 (5Z,11Z,14Z)-8,9-dihydroxyicosatrienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84032 CL:0002037 CD2-positive, CD5-positive, CD44-positive alpha-beta intraepithelial T cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002037 memory alpha beta IEL Intraepithelial T cells with a memory phenotype of CD2-positive, CD5-positive, and CD44-positive. CHEBI:84031 (5Z,8Z,14Z)-11,12-dihydroxyicosatrienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84031 CL:0002039 immature NK T cell stage I biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002039 A CD24-high, CD4-low, CD8-low, CD44-negative, NK1.1-negative NK T cell. CL:0002030 Fc-epsilon RIalpha-high basophil progenitor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002030 A lineage negative, Sca1-negative basophil progenitor cell that is Fc epsilon RIalpha-high. UBERON:0002597 principal sensory nucleus of trigeminal nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002597 principal sensory nucleus of the trigeminal nerve|nucleus sensibilis superior nervi trigemini|main sensory nucleus|trigeminal V principal sensory nucleus|pontine nucleus|principal sensory nucleus of trigeminal nerve|principal sensory nucleus of the trigeminal|primary nucleus of the trigeminal nerve|trigeminal nerve superior sensory nucleus|main sensory nucleus of cranial nerve v|nucleus sensorius principalis nervi trigemini|trigeminal V chief sensory nucleus|principal sensory nucleus|pontine nucleus of the trigeminal nerve|nucleus pontinus nervi trigemini|chief sensory trigeminal nucleus|chief trigeminal sensory nucleus|nucleus sensorius superior nervi trigemini|principal sensory trigeminal nucleus|principal trigeminal nucleus|chief sensory nucleus|nucleus pontinus nervi trigeminalis|superior trigeminal nucleus|superior trigeminal sensory nucleus|nucleus principalis nervi trigemini The principal sensory nucleus (or chief sensory nucleus of V) is a group of second order neurons which have cell bodies in the dorsal Pons. It receives information about discriminative sensation and light touch of the face as well as conscious proprioception of the jaw via first order neurons of CN V. Most of the sensory information crosses the midline and travels to the contralateral ventral posteriomedial (VPM) of the thalamus via the Ventral Trigeminothalamic Tract, but information of the oral cavity travels to the ipsilateral Ventral Posteriomedial (VPM) of the thalamus via the Dorsal Trigeminothalamic Tract. [WP,unvetted]. CL:0002032 hematopoietic oligopotent progenitor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002032 A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities. CL:0002031 hematopoietic lineage restricted progenitor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002031 A hematopoietic progenitor cell that is capable of developing into only one lineage of hematopoietic cells. GO:0046462 monoacylglycerol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046462 monoacylglycerol metabolism|monoglyceride metabolic process|monoglyceride metabolism The chemical reactions and pathways involving monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified. CHEBI:25710 organophosphorus compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25710 GO:0046461 neutral lipid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046461 neutral lipid breakdown|neutral lipid degradation|neutral lipid catabolism The chemical reactions and pathways resulting in the breakdown of neutral lipids, lipids only soluble in solvents of very low polarity. GO:0046460 neutral lipid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046460 neutral lipid biosynthesis|neutral lipid anabolism|neutral lipid synthesis|neutral lipid formation The chemical reactions and pathways resulting in the formation of neutral lipids, lipids only soluble in solvents of very low polarity. CHEBI:25713 organosilicon compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25713 CHEBI:60081 viomycin(3+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60081 CHEBI:25712 organoselenium compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25712 CHEBI:25711 organophosphorus insecticide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25711 CHEBI:60080 O-phosphoviomycin(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60080 CHEBI:60083 galactitol 1-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60083 CL:0002009 macrophage dendritic cell progenitor biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002009 MDP A progenitor cell that can give rise to plasmacytoid and myeloid dendritic cells, and to monocytes and macrophages. GO:0046469 platelet activating factor metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046469 PAF metabolic process|PAF metabolism|platelet activating factor metabolism The chemical reactions and pathways involving platelet activating factor, 1-O-alkyl-2-acetyl-sn-glycerol 3-phosphocholine, where alkyl = hexadecyl or octadecyl. Platelet activating factor is an inflammatory mediator released from a variety of cells in response to various stimuli. CHEBI:60082 vinca alkaloid cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60082 CL:0002008 CD34-positive, CD38-positive eosinophil progenitor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002008 A lineage marker-negative, CD34-positive, CD38-positive, IL3r-alpha-positive, IL5r-alpha-positive, and CD45RA-negative eosinophil progenitor cell. GO:0046468 phosphatidyl-N-monomethylethanolamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046468 PMME metabolic process|PMME metabolism|phosphatidyl-N-monomethylethanolamine metabolism The chemical reactions and pathways involving phosphatidyl-N-monomethylethanolamine (PMME), a derivative of phosphatidylethanolamine with a methylated amine group. Present in trace levels in plants and slightly higher in bacteria. CHEBI:60085 phosphoethanolamine-Kdo2-lipid A(6-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60085 GO:0046467 membrane lipid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046467 membrane lipid anabolism|membrane lipid synthesis|membrane lipid formation|membrane lipid biosynthesis The chemical reactions and pathways resulting in the formation of membrane lipids, any lipid found in or associated with a biological membrane. CHEBI:60084 D-glucitol 6-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60084 GO:0046466 membrane lipid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046466 membrane lipid catabolism|membrane lipid peroxidation|membrane lipid degradation|membrane lipid breakdown The chemical reactions and pathways resulting in the breakdown of membrane lipids, any lipid found in or associated with a biological membrane. CHEBI:60087 3-(cis-5,6-dihydroxycyclohexa-1,3-dienyl)propanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60087 GO:0046465 dolichyl diphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046465 dolichyl diphosphate metabolism The chemical reactions and pathways involving dolichyl diphosphate, a diphosphorylated dolichol derivative. In eukaryotes, these function as carriers of mono- and oligosaccharide residues in the glycosylation of lipids and proteins within intracellular membranes. CHEBI:60086 lipid A oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60086 GO:0046464 acylglycerol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046464 acylglycerol degradation|acylglycerol breakdown|acylglycerol catabolism The chemical reactions and pathways resulting in the breakdown of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids. GO:0046463 acylglycerol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046463 acylglycerol anabolism|acylglycerol synthesis|acylglycerol formation|acylglycerol biosynthesis The chemical reactions and pathways resulting in the formation of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids. CL:0002001 CD34-positive, CD38-positive granulocyte monocyte progenitor biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002001 A granulocyte monocyte progenitor is CD34-positive, CD38-positive, IL-3receptor-alpha-positive and is CD45RA-negative. CL:0002000 Kit-positive erythroid progenitor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002000 c- Kit-positive erythroid progenitor cell An erythroid progenitor cell is Kit-positive, Ly6A-negative, CD41-negative, CD127-negative, and CD123-negative. This cell type is also described as being lin-negative, Kit-positive, CD150-negative, CD41-negative, CD105-positive, and FcgR-negative. CHEBI:84046 pyoverdine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84046 CL:0002003 CD34-positive, GlyA-negative erythroid progenitor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002003 An erythroid progenitor cell that is CD34-positive and is GlyA-negative. CL:0002002 Kit-positive granulocyte monocyte progenitor biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002002 A granulocyte monocyte progenitor that is Kit-positive, CD34-positive, Fc-gamma receptor II/II-positive, and is Sca-1-negative, Il7ra-negative, Cxc3r1-negative, and CD90-negative. CL:0002005 CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002005 A megakaryocyte erythroid progenitor cell is CD34-positive, CD38-positive and is IL3-receptor alpha-negative and CD45RA-negative. GO:0071429 snRNA-containing ribonucleoprotein complex export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071429 snRNA-containing ribonucleoprotein complex transport from nucleus to cytoplasm|snRNA-containing ribonucleoprotein complex nucleus export|snRNA-containing ribonucleoprotein complex export from cell nucleus|snRNA-containing RNP export from nucleus The directed movement of a ribonucleoprotein complex that contains small nuclear RNA from the nucleus to the cytoplasm. CL:0002004 CD34-negative, GlyA-negative proerythroblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002004 A proerythoblast that is CD34-negative and GlyA-negative. CHEBI:84042 2,3-dipalmitoyl-alpha,alpha-trehalose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84042 GO:0071428 rRNA-containing ribonucleoprotein complex export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071428 rRNA-containing RNP export from nucleus|rRNA-containing ribonucleoprotein complex nucleus export|rRNA-containing ribonucleoprotein complex export from cell nucleus|rRNA-containing ribonucleoprotein complex transport from nucleus to cytoplasm The directed movement of a ribonucleoprotein complex that contains ribosomal RNA from the nucleus to the cytoplasm. CL:0002007 Kit-low, CD34-positive eosinophil progenitor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002007 A lineage marker-negative, CD34-positive, IL5r-alpha-positive, and Sca1-negative eosinophil progenitor cell. CHEBI:84041 2-O-palmitoyl-alpha,alpha-trehalose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84041 GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071427 mRNA-containing ribonucleoprotein complex nucleus export|mRNA-containing ribonucleoprotein complex export from cell nucleus|mRNA-containing RNP export from nucleus|mRNA-containing ribonucleoprotein complex transport from nucleus to cytoplasm The directed movement of a ribonucleoprotein complex that contains messenger RNA from the nucleus to the cytoplasm. CL:0002006 Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002006 A megakaryocyte erythroid progenitor cell that is Kit-positive and is Sca1-negative, CD34-negative, CD90-negative, IL7r-alpha-negative and Fcgr II/III-low. GO:0071426 ribonucleoprotein complex export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071426 ribonucleoprotein complex transport from nucleus to cytoplasm|ribonucleoprotein complex export from cell nucleus|RNP export from nucleus|ribonucleoprotein complex nucleus export The directed movement of a ribonucleoprotein complex from the nucleus to the cytoplasm. CHEBI:25718 ornithine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25718 GO:0071425 hematopoietic stem cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071425 hemopoietic stem cell proliferation The expansion of a hematopoietic stem cell population by cell division. A hematopoietic stem cell is a stem cell from which all cells of the lymphoid and myeloid lineages develop. CHEBI:25717 organotin compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25717 GO:0071424 rRNA (cytosine-N4-)-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071424 Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N4-methylcytosine. CHEBI:25716 organothiophosphorus compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25716 GO:0071423 malate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071423 transmembrane malate transport|malate membrane transport A process in which a malate ion is transported across a membrane. CHEBI:25715 organothiophosphate insecticide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25715 GO:0071422 succinate transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071422 succinate membrane transport|transmembrane succinate transport The process in which succinate is transported across a membrane. UBERON:0002583 commissure of superior colliculus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002583 commissura colliculi superioris|commissure of the superior colliculus|intertectal commissure|commissure of optic tectum|superior colliculus commissure|optic tectum commissure|commissure of the superior colliculi|commissura colliculi superior|commissure of cranial colliculus|commissura colliculorum superiorum|commissura colliculorum cranialium|commissure of superior colliculi|commissure of anterior colliculus|anterior corpus quadrigeminum commissure|commissura colliculorum rostralium|commissure of anterior corpus quadrigeminum|cranial colliculus commissure|anterior colliculus commissure A commissure that is part of a superior colliculus [Automatically generated definition]. GO:0071421 manganese ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071421 transmembrane manganese transport|manganese ion membrane transport A process in which a manganese ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. GO:0071420 cellular response to histamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071420 cellular response to histamine stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter. GO:1900309 regulation of maltoheptaose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900309 regulation of maltoheptaose metabolism Any process that modulates the frequency, rate or extent of maltoheptaose metabolic process. GO:0046473 phosphatidic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046473 phosphatidic acid metabolism The chemical reactions and pathways involving phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids. GO:0046472 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046472 GO:1900308 positive regulation of maltoheptaose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900308 up regulation of maltoheptaose transport|activation of maltoheptaose transport|up-regulation of maltoheptaose transport|upregulation of maltoheptaose transport Any process that activates or increases the frequency, rate or extent of maltoheptaose transport. GO:0046471 phosphatidylglycerol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046471 phosphatidylglycerol metabolism The chemical reactions and pathways involving phosphatidylglycerols, any of a class of phospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol. They are important constituents of cell membranes. GO:0046470 phosphatidylcholine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046470 phosphatidylcholine metabolism The chemical reactions and pathways involving phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. They are important constituents of cell membranes. CHEBI:60090 7-hydroxyflavon-3-olate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60090 GO:1900305 positive regulation of laminaritriose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900305 up-regulation of laminaritriose transport|activation of laminaritriose transport|up regulation of laminaritriose transport|upregulation of laminaritriose transport Any process that activates or increases the frequency, rate or extent of laminaritriose transport. GO:1900304 negative regulation of laminaritriose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900304 down-regulation of laminaritriose transport|downregulation of laminaritriose transport|down regulation of laminaritriose transport|inhibition of laminaritriose transport Any process that stops, prevents or reduces the frequency, rate or extent of laminaritriose transport. CHEBI:60092 SL659 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60092 GO:1900307 negative regulation of maltoheptaose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900307 downregulation of maltoheptaose transport|down-regulation of maltoheptaose transport|inhibition of maltoheptaose transport|down regulation of maltoheptaose transport Any process that stops, prevents or reduces the frequency, rate or extent of maltoheptaose transport. CHEBI:60091 alpha,alpha-trehalose-2-sulfate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60091 GO:1900306 regulation of maltoheptaose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900306 Any process that modulates the frequency, rate or extent of maltoheptaose transport. GO:1900301 negative regulation of laminarabiose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900301 down regulation of laminarabiose transport|downregulation of laminarabiose transport|down-regulation of laminarabiose transport|inhibition of laminarabiose transport Any process that stops, prevents or reduces the frequency, rate or extent of laminarabiose transport. GO:1900300 regulation of laminarabiose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900300 Any process that modulates the frequency, rate or extent of laminarabiose transport. CL:0002019 Ly-76 high reticulocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002019 A reticulocyte that is Ly76-high and is Kit-negative. GO:0046479 glycosphingolipid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046479 glycosphingolipid degradation|glycosphingolipid catabolism|glycosphingolipid breakdown The chemical reactions and pathways resulting in the breakdown of glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide. GO:1900303 regulation of laminaritriose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900303 Any process that modulates the frequency, rate or extent of laminaritriose transport. CHEBI:60096 poly(glycerol phosphate) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60096 GO:1900302 positive regulation of laminarabiose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900302 upregulation of laminarabiose transport|up regulation of laminarabiose transport|activation of laminarabiose transport|up-regulation of laminarabiose transport Any process that activates or increases the frequency, rate or extent of laminarabiose transport. GO:0046478 lactosylceramide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046478 lactosylceramide metabolism The chemical reactions and pathways involving lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. They are the precursors of both gangliosides and globosides. GO:0046477 glycosylceramide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046477 glycosylceramide catabolism|glycosylceramide degradation|glycosylceramide breakdown The chemical reactions and pathways resulting in the breakdown of glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group. GO:0046476 glycosylceramide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046476 glycosylceramide synthesis|glycosylceramide formation|glycosylceramide biosynthesis|glycosylceramide anabolism The chemical reactions and pathways resulting in the formation of glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group. GO:0046475 glycerophospholipid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046475 glycerophospholipid breakdown|phosphoglyceride catabolism|phosphoglyceride catabolic process|glycerophospholipid degradation|glycerophospholipid catabolism The chemical reactions and pathways resulting in the breakdown of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue. CHEBI:84059 octyl palmitate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84059 GO:0046474 glycerophospholipid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046474 glycerophospholipid biosynthesis|glycerophospholipid anabolism|glycerophospholipid synthesis|phosphoglyceride biosynthesis|phosphoglyceride biosynthetic process|glycerophospholipid formation The chemical reactions and pathways resulting in the formation of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue. CL:0002012 Kit-low proerythroblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002012 A proerythoblast that is Kit-low, Lyg76-positive, and CD71-positive. CL:0002011 Kit-positive macrophage dendritic cell progenitor biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002011 murine MDP A progenitor cell that can give rise to plasmacytoid and myeloid dendritic cells, and to monocytes and macrophages. Marker for this cell is Kit-high, CD115-positive, CD135-positive, Cx3cr1-positive, and is Il7ra-negative. CL:0002014 Kit-negative, Ly-76 high basophilic erythroblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002014 A basophilic erythroblast that is Lyg 76-high and is Kit-negative. CHEBI:84055 pentose phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84055 CL:0002013 GlyA-positive basophillic erythroblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002013 A basophilic erythroblast that is GlyA-positive. CL:0002016 CD71-low, GlyA-positive polychromatic erythroblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002016 A polychromatiic erythroblast that is Gly-A-positive and CD71-low. GO:0071419 cellular response to amphetamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071419 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine. CL:0002015 Kit-negative, Ly-76 high polychromatophilic erythroblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002015 late basophilic and polychromatophilic erythroblast A polychromatophilic erythroblast that is Lyg 76-high and is Kit-negative. GO:0071418 cellular response to amine stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071418 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups. GO:0071417 cellular response to organonitrogen compound biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071417 cellular response to organic nitrogen Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond. CL:0002018 CD71-negative, GlyA-positive orthochromatic erythroblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002018 An erythroblast that is GlyA-positive and CD71-negative. GO:0071416 cellular response to tropane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071416 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tropane stimulus. Tropane is a nitrogenous bicyclic organic compound mainly known for a group of alkaloids derived from it (called tropane alkaloids), which include, among others, atropine and cocaine. CL:0002017 Kit-negative, Ly-76 high orthochromatophilic erythroblasts biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002017 An orthochromatophilic erythroblast that is ter119-high, CD71-low, and Kit-negative. GO:0071415 cellular response to purine-containing compound biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071415 cellular response to purine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purine-containing compound stimulus. GO:0071414 cellular response to methotrexate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071414 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methotrexate stimulus. Methotrexate is 4-amino-10-methylformic acid, a folic acid analogue that is a potent competitive inhibitor of dihydrofolate reductase. CHEBI:25728 osmolyte biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25728 GO:0071413 cellular response to hydroxyisoflavone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071413 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyisoflavone stimulus. GO:0071412 cellular response to genistein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071412 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a genistein stimulus. GO:0071411 cellular response to fluoxetine biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0071411 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor. GO:0071410 cellular response to cyclopentenone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071410 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclopentenone stimulus. Cyclopentenones are oxylipins derived from polyunsaturated fatty acids. They are structurally similar to jasmonic acid, but contain a reactive unsaturated carbonyl structure in the cyclo-ring. Cyclopentenones include phytoprostanes and 12-oxo-phytodienoic acid. CL:0002010 pre-conventional dendritic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_0002010 A lin-negative, MHC-II-negative, CD11c-positive, FLT3-positive cell with intermediate expression of SIRP-alpha. GO:0046484 oxazole or thiazole metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046484 oxazole or thiazole metabolism The chemical reactions and pathways involving oxazole or thiazole, five-membered heterocyclic ring structures containing an oxygen and a sulfur, respectively, in the 1-position and a nitrogen in the 3-position. GO:0071440 regulation of histone H3-K14 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071440 regulation of histone H3 acetylation at K14|regulation of histone H3K14 acetylation Any process that modulates the frequency, rate or extent of the addition of an acetyl group to histone H3 at position 14 of the histone. GO:1900319 negative regulation of methane biosynthetic process from dimethylamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900319 inhibition of methane biosynthetic process from dimethylamine|down regulation of methane biosynthetic process from dimethylamine|downregulation of methane biosynthetic process from dimethylamine|down-regulation of methane biosynthetic process from dimethylamine Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from dimethylamine. GO:0046483 heterocycle metabolic process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0046483 heterocycle metabolism The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings). GO:0046482 para-aminobenzoic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046482 para-aminobenzoic acid metabolism|PABA metabolic process|4-aminobenzoic acid metabolic process|vitamin Bx metabolic process|p-aminobenzoic acid metabolic process|vitamin Bx metabolism|p-aminobenzoic acid metabolism|4-aminobenzoic acid metabolism|PABA metabolism The chemical reactions and pathways involving para-aminobenzoic acid, an intermediate in the synthesis of folic acid, a compound which some organisms, e.g. prokaryotes, eukaryotic microbes, and plants, can synthesize de novo. Others, notably mammals, cannot. In yeast, it is present as a factor in the B complex of vitamins. GO:0046481 digalactosyldiacylglycerol synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046481 KEGG_REACTION:R04469|RHEA:10520|Wikipedia:Digalactosyldiacylglycerol_synthase|EC:2.4.1.241|MetaCyc:RXN-1225 UDP-galactose-dependent digalactosyldiacylglycerol synthase activity|UDP-galactose:3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol 6-alpha-galactosyltransferase activity|DGDG synthase activity|UDP-galactose-dependent DGDG synthase activity|UDP-galactose:MGDG galactosyltransferase activity|DGD2|DGD1 Catalysis of the reaction: 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + UDP-D-galactose = 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-1,2-diacyl-sn-glycerol + H(+) + UDP. GO:1900316 negative regulation of maltopentaose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900316 inhibition of maltopentaose transport|down regulation of maltopentaose transport|downregulation of maltopentaose transport|down-regulation of maltopentaose transport Any process that stops, prevents or reduces the frequency, rate or extent of maltopentaose transport. GO:0046480 galactolipid galactosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046480 RHEA:15921|EC:2.4.1.184|MetaCyc:RXN-1226 GGGT activity|digalactosyldiacylglycerol synthase activity|DGDG synthase activity|3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol:mono-3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol beta-D-galactosyltransferase activity|galactolipid:galactolipid galactosyltransferase activity|galactolipid-galactolipid galactosyltransferase activity|interlipid galactosyltransferase activity Catalysis of the reaction: 2 mono-beta-D-galactosyldiacylglycerol = alpha-D-galactosyl-beta-D-galactosyldiacylglycerol + 1,2-diacylglycerol. GO:1900315 regulation of maltopentaose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900315 Any process that modulates the frequency, rate or extent of maltopentaose transport. GO:1900318 regulation of methane biosynthetic process from dimethylamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900318 Any process that modulates the frequency, rate or extent of methane biosynthetic process from dimethylamine. GO:1900317 positive regulation of maltopentaose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900317 up-regulation of maltopentaose transport|upregulation of maltopentaose transport|up regulation of maltopentaose transport|activation of maltopentaose transport Any process that activates or increases the frequency, rate or extent of maltopentaose transport. GO:1900312 regulation of maltohexaose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900312 Any process that modulates the frequency, rate or extent of maltohexaose transport. GO:1900311 positive regulation of maltoheptaose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900311 up-regulation of maltoheptaose metabolic process|positive regulation of maltoheptaose metabolism|up regulation of maltoheptaose metabolism|upregulation of maltoheptaose metabolic process|upregulation of maltoheptaose metabolism|up regulation of maltoheptaose metabolic process|activation of maltoheptaose metabolic process|up-regulation of maltoheptaose metabolism|activation of maltoheptaose metabolism Any process that activates or increases the frequency, rate or extent of maltoheptaose metabolic process. GO:1900314 positive regulation of maltohexaose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900314 up regulation of maltohexaose transport|upregulation of maltohexaose transport|up-regulation of maltohexaose transport|activation of maltohexaose transport Any process that activates or increases the frequency, rate or extent of maltohexaose transport. GO:0046489 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046489 GO:1900313 negative regulation of maltohexaose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900313 down-regulation of maltohexaose transport|downregulation of maltohexaose transport|down regulation of maltohexaose transport|inhibition of maltohexaose transport Any process that stops, prevents or reduces the frequency, rate or extent of maltohexaose transport. PR:000021195 peptide YY proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000021195 PYY/ClvPrd A peptide YY that has been processed by proteolytic cleavage. GO:0046488 phosphatidylinositol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046488 PtdIns metabolic process|phosphoinositide metabolism|phosphatidylinositol metabolism|phosphoinositide metabolic process|PtdIns metabolism The chemical reactions and pathways involving phosphatidylinositol, any glycophospholipid in which a sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol. GO:0046487 glyoxylate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046487 glyoxylate metabolism The chemical reactions and pathways involving glyoxylate, the anion of glyoxylic acid, HOC-COOH. GO:1900310 negative regulation of maltoheptaose metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900310 inhibition of maltoheptaose metabolic process|negative regulation of maltoheptaose metabolism|down-regulation of maltoheptaose metabolism|downregulation of maltoheptaose metabolism|down regulation of maltoheptaose metabolism|down regulation of maltoheptaose metabolic process|inhibition of maltoheptaose metabolism|downregulation of maltoheptaose metabolic process|down-regulation of maltoheptaose metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of maltoheptaose metabolic process. GO:0046486 glycerolipid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046486 glycerolipid metabolism The chemical reactions and pathways involving glycerolipids, any lipid with a glycerol backbone. Diacylglycerol and phosphatidate are key lipid intermediates of glycerolipid biosynthesis. GO:0046485 ether lipid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046485 Wikipedia:Ether_lipid ether lipid metabolism|plasmalogen metabolic process The chemical reactions and pathways involving ether lipids, lipids that contain (normally) one lipid alcohol in ether linkage to one of the carbon atoms (normally C-1) of glycerol. CHEBI:84069 pentanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84069 CHEBI:84067 tetradecanal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84067 CHEBI:84066 stearyl palmitate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84066 CHEBI:84065 arachidyl palmitate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84065 CHEBI:84064 myristyl palmitate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84064 CHEBI:84063 decyl palmitate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84063 GO:0071449 cellular response to lipid hydroperoxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071449 cellular response to LHPO Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid hydroperoxide stimulus. Lipid hydroperoxide is the highly reactive primary oxygenated products of polyunsaturated fatty acids. CHEBI:84062 nonyl palmitate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84062 GO:0071448 cellular response to alkyl hydroperoxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071448 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkyl hydroperoxide stimulus. Alkyl hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH, where the substituent is an alkyl group. GO:0071447 cellular response to hydroperoxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071447 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroperoxide stimulus. Hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH. GO:0071446 cellular response to salicylic acid stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071446 cellular response to salicylate stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salicylic acid stimulus. GO:0071445 obsolete cellular response to protein stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071445 cellular response to protein stimulus OBSOLETE. Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein stimulus. GO:0071444 cellular response to pheromone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071444 cellular pheromone response Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus. GO:0071443 tDNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071443 Interacting selectively and non-covalently with DNA sequences encoding transfer RNA. GO:0071442 positive regulation of histone H3-K14 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071442 stimulation of histone H3-K14 acetylation|up-regulation of histone H3-K14 acetylation|positive regulation of histone H3K14 acetylation|activation of histone H3-K14 acetylation|up regulation of histone H3-K14 acetylation|positive regulation of histone H3 acetylation at K14|upregulation of histone H3-K14 acetylation Any process that activates or increases the frequency, rate or extent of the addition of an acetyl group to histone H3 at position 14 of the histone. GO:0071441 negative regulation of histone H3-K14 acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071441 negative regulation of histone H3K14 acetylation|down-regulation of histone H3-K14 acetylation|downregulation of histone H3-K14 acetylation|negative regulation of histone H3 acetylation at K14|down regulation of histone H3-K14 acetylation|inhibition of histone H3-K14 acetylation Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of an acetyl group to histone H3 at position 14 of the histone. GO:0046495 nicotinamide riboside metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046495 nicotinamide riboside metabolism|N-ribosylnicotinamide metabolic process The chemical reactions and pathways involving nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide. GO:0046494 rhizobactin 1021 metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046494 rhizobactin 1021 metabolism The chemical reactions and pathways involving rhizobactin 1021, (E)-4-((3-(acetylhydroxyamino)propyl)-amino)-2-hydroxy-(2-(2-(3-(hydroxy(1-oxo-2-decenyl)amino)propyl)amino)-2-oxoethyl)-4-oxobutanoic acid, a siderophore produced by Sinorhizobium meliloti. GO:0046493 lipid A metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046493 lipid A metabolism The chemical reactions and pathways involving lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of four to six fatty acyl chains linked to two glucosamine residues. Further modifications of the backbone are common. GO:0046492 heme B metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046492 protoheme metabolic process|heme B metabolism|protoheme metabolism|haem B metabolic process|haem B metabolism The chemical reactions and pathways involving heme b, a Fe(II) porphyrin complex readily isolated from the hemoglobin of beef blood, but also found in other proteins including other hemoglobins, myoglobins, cytochromes P-450, catalases, peroxidases as well as b type cytochromes. GO:1900327 regulation of mannotriose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900327 Any process that modulates the frequency, rate or extent of mannotriose transport. CHEBI:25703 organic phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25703 GO:0046491 L-methylmalonyl-CoA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046491 L-methylmalonyl-CoA metabolism The chemical reactions and pathways involving L-methylmalonyl-CoA, the L-enantiomer of 2-carboxypropanoyl-CoA. S-methylmalonyl-CoA is an intermediate in the beta oxidation of odd-numbered fatty acids in animals. GO:1900326 positive regulation of maltotriulose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900326 up regulation of maltotriulose transport|activation of maltotriulose transport|up-regulation of maltotriulose transport|upregulation of maltotriulose transport Any process that activates or increases the frequency, rate or extent of maltotriulose transport. GO:0046490 isopentenyl diphosphate metabolic process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0046490 IPP metabolism|isopentenyl pyrophosphate metabolic process|isopentenyl pyrophosphate metabolism|isopentenyl diphosphate metabolism|IPP metabolic process The chemical reactions and pathways involving isopentenyl diphosphate, an isomer of dimethylallyl diphosphate and the key precursor of all isoprenoids. CHEBI:25702 organic peroxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25702 GO:1900329 positive regulation of mannotriose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900329 up regulation of mannotriose transport|activation of mannotriose transport|up-regulation of mannotriose transport|upregulation of mannotriose transport Any process that activates or increases the frequency, rate or extent of mannotriose transport. CHEBI:25701 organic oxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25701 GO:1900328 negative regulation of mannotriose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900328 downregulation of mannotriose transport|down-regulation of mannotriose transport|inhibition of mannotriose transport|down regulation of mannotriose transport Any process that stops, prevents or reduces the frequency, rate or extent of mannotriose transport. GO:1900323 positive regulation of maltotetraose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900323 upregulation of maltotetraose transport|up regulation of maltotetraose transport|activation of maltotetraose transport|up-regulation of maltotetraose transport Any process that activates or increases the frequency, rate or extent of maltotetraose transport. GO:1900322 negative regulation of maltotetraose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900322 down regulation of maltotetraose transport|downregulation of maltotetraose transport|down-regulation of maltotetraose transport|inhibition of maltotetraose transport Any process that stops, prevents or reduces the frequency, rate or extent of maltotetraose transport. GO:1900325 negative regulation of maltotriulose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900325 down-regulation of maltotriulose transport|inhibition of maltotriulose transport|down regulation of maltotriulose transport|downregulation of maltotriulose transport Any process that stops, prevents or reduces the frequency, rate or extent of maltotriulose transport. GO:1900324 regulation of maltotriulose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900324 Any process that modulates the frequency, rate or extent of maltotriulose transport. GO:0046499 S-adenosylmethioninamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046499 S-adenosylmethioninamine metabolism The chemical reactions and pathways involving S-adenosylmethioninamine, (5-deoxy-5-adenosyl)(3-aminopropyl) methylsulfonium salt. GO:0046498 S-adenosylhomocysteine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046498 S-adenosylhomocysteine metabolism The chemical reactions and pathways involving S-adenosylhomocysteine; the L-enantiomer is formed from S-adenosylmethionine and is a strong inhibitor of S-adenosylmethionine-mediated methylation reactions. It can be cleaved to form adenosine and homocysteine. GO:1900321 regulation of maltotetraose transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900321 Any process that modulates the frequency, rate or extent of maltotetraose transport. GO:0046497 nicotinate nucleotide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046497 nicotinate nucleotide metabolism The chemical reactions and pathways involving nicotinamide nucleotides, any nucleotide that contains combined nicotinate (pyridine 3-carboxylic acid, or niacin). GO:0046496 nicotinamide nucleotide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046496 nicotinamide nucleotide metabolism The chemical reactions and pathways involving nicotinamide nucleotides, any nucleotide that contains combined nicotinamide. GO:1900320 positive regulation of methane biosynthetic process from dimethylamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900320 activation of methane biosynthetic process from dimethylamine|up-regulation of methane biosynthetic process from dimethylamine|upregulation of methane biosynthetic process from dimethylamine|up regulation of methane biosynthetic process from dimethylamine Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from dimethylamine. CHEBI:597326 pyridoxal 5'-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_597326 CHEBI:84076 L-histidine derivative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84076 GO:0071439 clathrin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071439 clathrin triskelion A protein complex that consists of three clathrin heavy chains and three clathrin light chains, organized into a symmetrical three-legged structure called a triskelion. In clathrin-coated vesicles clathrin is the main component of the coat and forms a polymeric mechanical scaffold on the vesicle surface. GO:0071438 obsolete invadopodium membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071438 OBSOLETE. The portion of the plasma membrane surrounding an invadopodium. GO:0071437 obsolete invadopodium biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071437 OBSOLETE. A cell projection that emerges from the ECM-facing surface of a cell, is enriched in actin and associated cytoskeletal proteins, and displays localized proteolytic activity toward the substrate. CHEBI:25707 organometallic compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25707 CHEBI:84072 hexadecyl elaidate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84072 GO:0071436 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0071436 CHEBI:25706 organomercury compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25706 GO:0071435 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0071435 CHEBI:25705 organochlorine insecticide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25705 GO:0071434 cell chemotaxis to angiotensin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071434 angiotensin mediated chemotaxis|angiotensin-mediated cell chemotaxis The directed movement of a motile cell in response to the presence of angiotensin. CHEBI:25704 organic sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25704 GO:0071433 cell wall repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071433 A process of cell wall organization that results in the restoration of the cell wall following damage. GO:0071432 peptide mating pheromone maturation involved in positive regulation of conjugation with cellular fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071432 alpha-factor maturation|a-factor processing (proteolytic)|mating-type peptide pheromone maturation involved in conjugation with cellular fusion|peptide mating pheromone processing involved in conjugation with cellular fusion|peptide mating pheromone formation involved in conjugation with cellular fusion The formation of a mature peptide mating pheromone by proteolysis and/or modification of a peptide precursor, occurring in the context of conjugation with cellular fusion. GO:0071431 tRNA-containing ribonucleoprotein complex export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071431 tRNA-containing ribonucleoprotein complex transport from nucleus to cytoplasm|tRNA-containing RNP export from nucleus|tRNA-containing ribonucleoprotein complex nucleus export|tRNA-containing ribonucleoprotein complex export from cell nucleus The directed movement of a ribonucleoprotein complex that contains transfer RNA from the nucleus to the cytoplasm. GO:0071430 pre-miRNA-containing ribonucleoprotein complex export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071430 pre-microRNA-containing ribonucleoprotein complex export from nucleus|pre-microRNA-containing RNP export from nucleus|pre-microRNA-containing ribonucleoprotein complex nucleus export|pre-microRNA-containing ribonucleoprotein complex export from cell nucleus|pre-microRNA-containing ribonucleoprotein complex transport from nucleus to cytoplasm The directed movement of a ribonucleoprotein complex that contains pre-microRNA from the nucleus to the cytoplasm. CHEBI:25708 organophosphate insecticide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_25708 GO:0071462 cellular response to water stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071462 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water. GO:0071461 cellular response to redox state biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071461 cellular redox signal response Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating redox state. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important. GO:0071460 cellular response to cell-matrix adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071460 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cell-matrix adhesion. GO:1900338 positive regulation of methane biosynthetic process from carbon monoxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900338 up-regulation of methane biosynthetic process from carbon monoxide|upregulation of methane biosynthetic process from carbon monoxide|up regulation of methane biosynthetic process from carbon monoxide|activation of methane biosynthetic process from carbon monoxide Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from carbon monoxide. OIO:hasExactSynonym has_exact_synonym biolink:OntologyClass go-plus http://www.geneontology.org/formats/oboInOwl#hasExactSynonym GO:1900337 negative regulation of methane biosynthetic process from carbon monoxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900337 inhibition of methane biosynthetic process from carbon monoxide|down regulation of methane biosynthetic process from carbon monoxide|downregulation of methane biosynthetic process from carbon monoxide|down-regulation of methane biosynthetic process from carbon monoxide Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from carbon monoxide. GO:1900339 regulation of methane biosynthetic process from formic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900339 Any process that modulates the frequency, rate or extent of methane biosynthetic process from formic acid. GO:1900334 negative regulation of methane biosynthetic process from 3-(methylthio)propionic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900334 downregulation of methane biosynthetic process from 3-(methylthio)propionic acid|down regulation of methane biosynthetic process from 3-(methylthio)propionic acid|inhibition of methane biosynthetic process from 3-(methylthio)propionic acid|down-regulation of methane biosynthetic process from 3-(methylthio)propionic acid Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from 3-(methylthio)propionic acid. GO:1900333 regulation of methane biosynthetic process from 3-(methylthio)propionic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900333 Any process that modulates the frequency, rate or extent of methane biosynthetic process from 3-(methylthio)propionic acid. GO:1900336 regulation of methane biosynthetic process from carbon monoxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900336 Any process that modulates the frequency, rate or extent of methane biosynthetic process from carbon monoxide. GO:1900335 positive regulation of methane biosynthetic process from 3-(methylthio)propionic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900335 up regulation of methane biosynthetic process from 3-(methylthio)propionic acid|upregulation of methane biosynthetic process from 3-(methylthio)propionic acid|up-regulation of methane biosynthetic process from 3-(methylthio)propionic acid|activation of methane biosynthetic process from 3-(methylthio)propionic acid Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from 3-(methylthio)propionic acid. GO:1900330 regulation of methane biosynthetic process from trimethylamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900330 Any process that modulates the frequency, rate or extent of methane biosynthetic process from trimethylamine. GO:1900332 positive regulation of methane biosynthetic process from trimethylamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900332 upregulation of methane biosynthetic process from trimethylamine|up-regulation of methane biosynthetic process from trimethylamine|activation of methane biosynthetic process from trimethylamine|up regulation of methane biosynthetic process from trimethylamine Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from trimethylamine. GO:1900331 negative regulation of methane biosynthetic process from trimethylamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900331 inhibition of methane biosynthetic process from trimethylamine|down-regulation of methane biosynthetic process from trimethylamine|downregulation of methane biosynthetic process from trimethylamine|down regulation of methane biosynthetic process from trimethylamine Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from trimethylamine. CHEBI:84087 human urinary metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84087 GO:0071469 cellular response to alkaline pH biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071469 cellular response to alkalinity|cellular response to basic pH Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH > 7. pH is a measure of the acidity or basicity of an aqueous solution. GO:0071468 cellular response to acidic pH biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071468 cellular response to acidity Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution. GO:0071467 cellular response to pH biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071467 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution. CHEBI:84080 palmityl laurate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84080 GO:0071466 cellular response to xenobiotic stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071466 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xenobiotic compound stimulus. Xenobiotic compounds are compounds foreign to living organisms. GO:0071465 cellular response to desiccation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071465 desiccation tolerance Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desiccation stimulus, extreme dryness resulting from the prolonged deprivation of water. GO:0071464 cellular response to hydrostatic pressure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071464 cellular response to static fluid pressure|cellular response to biomechanical stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it. GO:0071463 cellular response to humidity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071463 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a humidity stimulus, moisture in the atmosphere. GO:0071451 cellular response to superoxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071451 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion. GO:0071450 cellular response to oxygen radical biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071450 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion. GO:1900349 negative regulation of methane biosynthetic process from methylamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900349 down-regulation of methane biosynthetic process from methylamine|inhibition of methane biosynthetic process from methylamine|down regulation of methane biosynthetic process from methylamine|downregulation of methane biosynthetic process from methylamine Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from methylamine. GO:1900348 regulation of methane biosynthetic process from methylamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900348 Any process that modulates the frequency, rate or extent of methane biosynthetic process from methylamine. GO:1900345 regulation of methane biosynthetic process from methanethiol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900345 Any process that modulates the frequency, rate or extent of methane biosynthetic process from methanethiol. GO:1900344 positive regulation of methane biosynthetic process from dimethyl sulfide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900344 upregulation of methane biosynthetic process from dimethyl sulfide|up-regulation of methane biosynthetic process from dimethyl sulfide|activation of methane biosynthetic process from dimethyl sulfide|up regulation of methane biosynthetic process from dimethyl sulfide Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from dimethyl sulfide. GO:1900347 positive regulation of methane biosynthetic process from methanethiol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900347 activation of methane biosynthetic process from methanethiol|up regulation of methane biosynthetic process from methanethiol|upregulation of methane biosynthetic process from methanethiol|up-regulation of methane biosynthetic process from methanethiol Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from methanethiol. GO:1900346 negative regulation of methane biosynthetic process from methanethiol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900346 down-regulation of methane biosynthetic process from methanethiol|downregulation of methane biosynthetic process from methanethiol|down regulation of methane biosynthetic process from methanethiol|inhibition of methane biosynthetic process from methanethiol Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from methanethiol. GO:1900341 positive regulation of methane biosynthetic process from formic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900341 upregulation of methane biosynthetic process from formic acid|up regulation of methane biosynthetic process from formic acid|activation of methane biosynthetic process from formic acid|up-regulation of methane biosynthetic process from formic acid Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from formic acid. GO:1900340 negative regulation of methane biosynthetic process from formic acid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900340 down regulation of methane biosynthetic process from formic acid|downregulation of methane biosynthetic process from formic acid|down-regulation of methane biosynthetic process from formic acid|inhibition of methane biosynthetic process from formic acid Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from formic acid. GO:1900343 negative regulation of methane biosynthetic process from dimethyl sulfide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900343 downregulation of methane biosynthetic process from dimethyl sulfide|down regulation of methane biosynthetic process from dimethyl sulfide|inhibition of methane biosynthetic process from dimethyl sulfide|down-regulation of methane biosynthetic process from dimethyl sulfide Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from dimethyl sulfide. GO:1900342 regulation of methane biosynthetic process from dimethyl sulfide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900342 Any process that modulates the frequency, rate or extent of methane biosynthetic process from dimethyl sulfide. GO:1900350 positive regulation of methane biosynthetic process from methylamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900350 up regulation of methane biosynthetic process from methylamine|activation of methane biosynthetic process from methylamine|up-regulation of methane biosynthetic process from methylamine|upregulation of methane biosynthetic process from methylamine Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from methylamine. PR:000021170 parathyroid hormone proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000021170 PTH/ClvPrd A parathyroid hormone that has been processed by proteolytic cleavage. CHEBI:84095 2,6-dimethylheptanoyl carnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84095 GO:0071459 protein localization to chromosome, centromeric region biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071459 protein localisation to chromosome, centromeric region|protein localization to centromere|protein localization to chromosome, centric region Any process in which a protein is transported to, or maintained at, the centromeric region of a chromosome. GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071458 integral to cytosolic side of ER membrane|integral to cytosolic leaflet of endoplasmic reticulum membrane|integral to cytosolic side of endoplasmic reticulum membrane|integral to ER membrane, cytosolic side The component of the endoplasmic reticulum membrane consisting of the gene products that penetrate only the cytoplasmic side of the membrane. CHEBI:84092 4-(beta-D-glucopyranuronosyloxy)retinoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84092 GO:0071457 cellular response to ozone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071457 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ozone stimulus. GO:0071456 cellular response to hypoxia biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071456 cellular response to lowered oxygen tension|cellular response to hypoxic stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. GO:0071455 cellular response to hyperoxia biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071455 cellular response to increased oxygen tension|cellular response to hyperoxic stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension. CHEBI:84090 hydroxyretinoic glucuronide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84090 GO:0071454 cellular response to anoxia biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071454 cellular response to anoxic stress|cellular response to anaerobic conditions Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%. GO:0071453 cellular response to oxygen levels biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071453 cellular response to oxygen Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen. GO:0071452 cellular response to singlet oxygen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071452 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a singlet oxygen stimulus. Singlet oxygen is a dioxygen (O2) molecule in which two 2p electrons have similar spin. Singlet oxygen is more highly reactive than the form in which these electrons are of opposite spin, and it is produced in mutant chloroplasts lacking carotenoids and by leukocytes during metabolic burst. GO:0046602 regulation of mitotic centrosome separation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046602 Any process that modulates the frequency, rate or extent of the separation of duplicated centrosome components at the beginning of mitosis. GO:0046601 positive regulation of centriole replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046601 upregulation of centriole replication|up regulation of centriole replication|activation of centriole replication|stimulation of centriole replication|up-regulation of centriole replication Any process that activates or increases the frequency, rate or extent of centriole replication. GO:0046600 negative regulation of centriole replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046600 down regulation of centriole replication|downregulation of centriole replication|down-regulation of centriole replication|inhibition of centriole replication Any process that stops, prevents, or reduces the frequency, rate or extent of centriole replication. GO:0046609 obsolete voltage-gated sulfate antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046609 prestin|voltage gated sulfate antiporter activity|voltage-sensitive sulphate antiporter activity|voltage-dependent sulfate antiporter activity|voltage-sensitive sulfate antiporter activity OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + solute(in) = solute(in) + sulfate(out), by a channel in a cell membrane whose opening is governed by the membrane potential. GO:0046608 carotenoid isomerase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046608 Catalysis of the isomerization of poly-cis-carotenoids to all-trans-carotenoids. GO:0046607 positive regulation of centrosome cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046607 upregulation of centrosome cycle|stimulation of centrosome cycle|up-regulation of centrosome cycle|activation of centrosome cycle|up regulation of centrosome cycle Any process that activates or increases the frequency, rate or extent of the centrosome cycle. GO:0046606 negative regulation of centrosome cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046606 down regulation of centrosome cycle|inhibition of centrosome cycle|down-regulation of centrosome cycle|downregulation of centrosome cycle Any process that stops, prevents, or reduces the frequency, rate or extent of the centrosome cycle. GO:0046605 regulation of centrosome cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046605 Any process that modulates the frequency, rate or extent of the centrosome cycle, the processes of centrosome duplication and separation. GO:0046604 positive regulation of mitotic centrosome separation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046604 up regulation of mitotic centrosome separation|activation of mitotic centrosome separation|stimulation of mitotic centrosome separation|up-regulation of mitotic centrosome separation|upregulation of mitotic centrosome separation Any process that activates or increases the frequency, rate or extent of centrosome separation. GO:0046603 negative regulation of mitotic centrosome separation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046603 down-regulation of mitotic centrosome separation|inhibition of mitotic centrosome separation|down regulation of mitotic centrosome separation|downregulation of mitotic centrosome separation Any process that stops, prevents, or reduces the frequency, rate or extent of centrosome separation. CHEBI:45296 hexadecane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_45296 GO:0007009 plasma membrane organization biolink:BiologicalProcess go-plus goslim_chembl|goslim_generic http://purl.obolibrary.org/obo/GO_0007009 plasma membrane organisation|plasma membrane organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane. GO:0022620 vegetative cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022620 tube cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a vegetative cell. The vegetative cell is gives rise to the pollen tube. GO:0007008 outer mitochondrial membrane organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007008 outer mitochondrial membrane organisation|outer mitochondrial membrane organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial outer membrane. GO:0007007 inner mitochondrial membrane organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007007 inner mitochondrial membrane organisation|mitochondrial inner membrane organization|inner mitochondrial membrane organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial inner membrane. GO:0022622 root system development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022622 The process whose specific outcome is the progression of the root system over time, from its formation to the mature structure. GO:0007006 mitochondrial membrane organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007006 mitochondrial membrane organisation|mitochondrial membrane organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrial membrane, either of the lipid bilayer surrounding a mitochondrion. GO:0022621 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0022621 GO:0007005 mitochondrion organization biolink:BiologicalProcess go-plus goslim_chembl|goslim_yeast|goslim_pir|goslim_drosophila|goslim_generic|goslim_pombe http://purl.obolibrary.org/obo/GO_0007005 mitochondrion organization and biogenesis|mitochondria organization|mitochondrion organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components. GO:0046613 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046613 GO:0007004 telomere maintenance via telomerase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007004 telomerase-dependent telomere maintenance The maintenance of proper telomeric length by the addition of telomeric repeats by telomerase. GO:0046612 lysosomal proton-transporting V-type ATPase, V1 domain biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0046612 lysosomal hydrogen ion-transporting ATPase V1 domain The V1 domain of a proton-transporting V-type ATPase found in the lysosomal membrane. CHEBI:127343 17-(4-hydroxyphenyl)heptadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_127343 GO:0007003 obsolete telomere binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007003 telomere binding OBSOLETE. (Was not defined before being made obsolete). GO:0046611 lysosomal proton-transporting V-type ATPase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0046611 lysosomal hydrogen-translocating V-type ATPase complex|lysosomal membrane hydrogen-transporting ATPase A proton-transporting two-sector ATPase complex found in the lysosomal membrane, where it acts as a proton pump to mediate acidification of the lysosomal lumen. GO:0007002 obsolete centromere binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007002 centromere binding OBSOLETE. (Was not defined before being made obsolete). GO:0046610 lysosomal proton-transporting V-type ATPase, V0 domain biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0046610 lysosomal hydrogen ion-transporting ATPase V0 domain The V0 domain of a proton-transporting V-type ATPase found in the lysosomal membrane. GO:0007001 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007001 GO:0007000 nucleolus organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007000 nucleolus organisation|nucleolus organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleolus. GO:0046619 optic placode formation involved in camera-type eye formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046619 optic placode formation involved in camera-style eye|optic placode formation in camera-type eye Establishment and formation of the optic placode, paired ectodermal placodes that become invaginated to form the embryonic lens vesicles. GO:0046618 drug export biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046618 The directed movement of a drug, a substance used in the diagnosis, treatment or prevention of a disease, out of a cell or organelle. GO:0046617 obsolete nucleolar size increase (sensu Saccharomyces) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046617 nucleolar size increase (sensu Saccharomyces) OBSOLETE. The process of nucleolar expansion, as seen in Saccharomyces. CHEBI:142967 D-histidine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142967 GO:0046616 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046616 GO:0046615 obsolete re-entry into mitotic cell cycle after pheromone arrest (sensu Saccharomyces) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046615 re-entry into mitotic cell cycle after pheromone arrest (sensu Saccharomyces) OBSOLETE. The resumption of the Saccharomyces mitotic cell division cycle by pheromone-arrested cells that have not mated. GO:0046614 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046614 GO:0022624 proteasome accessory complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0022624 A protein complex, that caps one or both ends of the proteasome core complex and regulates entry into, or exit from, the proteasome core complex. GO:0022623 proteasome-activating nucleotidase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0022623 PAN A homohexameric complex that recognizes and unfolds core proteasome substrate proteins, and translocates them to the core complex in an ATP dependent manner. GO:0022626 cytosolic ribosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0022626 70S ribosome|80S ribosome A ribosome located in the cytosol. GO:0022625 cytosolic large ribosomal subunit biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0022625 prokaryotic large ribosomal subunit|60S ribosomal subunit|50S ribosomal subunit|eukaryotic ribosomal LSU The large subunit of a ribosome located in the cytosol. GO:0022628 chloroplast large ribosomal subunit biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0022628 chloroplast ribosomal large subunit complex|chloroplast ribosomal LSU complex The large subunit of a ribosome contained within a chloroplast. GO:0022627 cytosolic small ribosomal subunit biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0022627 prokaryotic small ribosomal subunit|eukaryotic ribosomal SSU|40S ribosomal subunit|30S ribosomal subunit The small subunit of a ribosome located in the cytosol. GO:0022629 chloroplast small ribosomal subunit biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0022629 chloroplast ribosomal SSU complex|chloroplast ribosomal small subunit complex The small subunit of a ribosome contained within a chloroplast. CHEBI:45285 pyrazinecarboxamide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_45285 GO:0022611 dormancy process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022611 multicellular organism dormancy process|spore dormancy process A developmental process in which dormancy (sometimes called a dormant state) is induced, maintained or broken. Dormancy is a suspension of most physiological activity and growth that can be reactivated. GO:0022610 biological adhesion biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0022610 The attachment of a cell or organism to a substrate, another cell, or other organism. Biological adhesion includes intracellular attachment between membrane regions. GO:0046624 sphingolipid transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046624 Reactome:R-HSA-9695890 Enables the directed movement of sphingolipids into, out of or within a cell, or between cells. Sphingolipids are a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). GO:0046623 sphingolipid floppase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046623 sphingolipid floppase activity (cytosolic to exoplasmic leaftlet)|sphingolipid flippase activity|sphingolipid-translocating ATPase activity Catalysis of the movement of a sphingolipid from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP. GO:0046622 positive regulation of organ growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046622 Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism. GO:0046621 negative regulation of organ growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046621 Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism. GO:0046620 regulation of organ growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046620 Any process that modulates the frequency, rate or extent of growth of an organ of an organism. GO:0046629 gamma-delta T cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046629 gamma-delta T-cell activation|gamma-delta T lymphocyte activation|gamma-delta T-lymphocyte activation The change in morphology and behavior of a gamma-delta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. GO:0046628 positive regulation of insulin receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046628 upregulation of insulin receptor signaling pathway|stimulation of insulin receptor signaling pathway|positive regulation of insulin receptor signalling pathway|activation of insulin receptor signaling pathway|up-regulation of insulin receptor signaling pathway|up regulation of insulin receptor signaling pathway Any process that increases the frequency, rate or extent of insulin receptor signaling. GO:0046627 negative regulation of insulin receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046627 downregulation of insulin receptor signaling pathway|down regulation of insulin receptor signaling pathway|inhibition of insulin receptor signaling pathway|negative regulation of insulin receptor signalling pathway|down-regulation of insulin receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of insulin receptor signaling. GO:0046626 regulation of insulin receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046626 regulation of insulin receptor signalling pathway Any process that modulates the frequency, rate or extent of insulin receptor signaling. CHEBI:142954 diacylglycerol 24:0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142954 GO:0046625 sphingolipid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046625 Interacting selectively and non-covalently with sphingolipids, a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). CHEBI:142953 didodecanoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142953 GO:0022613 ribonucleoprotein complex biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022613 ribonucleoprotein complex biogenesis and assembly|RNA-protein complex biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a complex containing RNA and proteins. Includes the biosynthesis of the constituent RNA and protein molecules, and those macromolecular modifications that are involved in synthesis or assembly of the ribonucleoprotein complex. GO:0022612 gland morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022612 The process in which the anatomical structures of a gland are generated and organized. GO:0022615 protein to membrane docking biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022615 protein-membrane docking The initial attachment of a protein to a target membrane, mediated by a proteins protruding from the target membrane. Docking requires only that the proteins come close enough to interact and adhere. GO:0022614 membrane to membrane docking biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022614 membrane-membrane docking The initial attachment of a membrane to a target membrane, mediated by proteins protruding from the two membranes. Docking requires only that the membranes come close enough for the proteins to interact and adhere. GO:0022617 extracellular matrix disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022617 A process that results in the breakdown of the extracellular matrix. GO:0022616 DNA strand elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022616 The DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand. GO:0022619 generative cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022619 The process in which a relatively unspecialized cell acquires specialized features of a generative cell. The generative cell gives rise to the sperm cells in the male gametophyte. GO:0022618 ribonucleoprotein complex assembly biolink:BiologicalProcess go-plus goslim_generic|goslim_chembl http://purl.obolibrary.org/obo/GO_0022618 RNP complex assembly|RNA-protein complex assembly|protein-RNA complex assembly The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex. GO:1900705 negative regulation of siderophore biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900705 down regulation of siderophore synthesis|inhibition of siderochrome biosynthesis|inhibition of siderochrome biosynthetic process|downregulation of siderophore anabolism|down-regulation of siderophore biosynthetic process, peptide modification|negative regulation of siderophore biosynthetic process, peptide modification|down regulation of siderophore formation|downregulation of siderophore synthesis|down-regulation of siderophore biosynthetic process|negative regulation of siderophore biosynthesis|down-regulation of siderophore biosynthesis|inhibition of siderophore biosynthetic process, peptide formation|down regulation of siderochrome biosynthesis|downregulation of siderophore formation|down regulation of siderochrome biosynthetic process|down-regulation of siderophore anabolism|negative regulation of siderophore anabolism|downregulation of siderophore biosynthetic process, peptide modification|downregulation of siderochrome biosynthetic process|downregulation of siderochrome biosynthesis|down-regulation of siderophore synthesis|negative regulation of siderophore synthesis|down regulation of siderophore biosynthetic process, peptide formation|downregulation of siderophore biosynthetic process|down regulation of siderophore biosynthetic process, peptide modification|downregulation of siderophore biosynthesis|down-regulation of siderophore formation|negative regulation of siderophore formation|downregulation of siderophore biosynthetic process, peptide formation|down regulation of siderophore biosynthesis|down regulation of siderophore biosynthetic process|negative regulation of siderochrome biosynthesis|inhibition of siderophore biosynthetic process|negative regulation of siderochrome biosynthetic process|down-regulation of siderochrome biosynthetic process|down-regulation of siderochrome biosynthesis|inhibition of siderophore biosynthetic process, peptide modification|inhibition of siderophore anabolism|inhibition of siderophore biosynthesis|inhibition of siderophore synthesis|negative regulation of siderophore biosynthetic process, peptide formation|down-regulation of siderophore biosynthetic process, peptide formation|down regulation of siderophore anabolism|inhibition of siderophore formation Any process that stops, prevents or reduces the frequency, rate or extent of siderophore biosynthetic process. GO:1900704 regulation of siderophore biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900704 regulation of siderophore synthesis|regulation of siderophore formation|regulation of siderochrome biosynthetic process|regulation of siderochrome biosynthesis|regulation of siderophore biosynthetic process, peptide modification|regulation of siderophore biosynthetic process, peptide formation|regulation of siderophore biosynthesis|regulation of siderophore anabolism Any process that modulates the frequency, rate or extent of siderophore biosynthetic process. GO:1900707 regulation of tensidol A biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900707 regulation of tensidol A anabolism|regulation of tensidol A synthesis|regulation of tensidol A formation|regulation of tensidol A biosynthesis Any process that modulates the frequency, rate or extent of tensidol A biosynthetic process. GO:1900706 positive regulation of siderophore biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900706 activation of siderophore biosynthetic process|up-regulation of siderophore biosynthesis|up-regulation of siderophore biosynthetic process|activation of siderophore biosynthetic process, peptide modification|upregulation of siderophore formation|up-regulation of siderophore biosynthetic process, peptide formation|upregulation of siderochrome biosynthetic process|up regulation of siderophore anabolism|upregulation of siderochrome biosynthesis|activation of siderophore biosynthesis|positive regulation of siderophore biosynthetic process, peptide modification|positive regulation of siderophore anabolism|up regulation of siderophore biosynthetic process, peptide modification|up regulation of siderophore synthesis|positive regulation of siderophore synthesis|positive regulation of siderophore biosynthesis|upregulation of siderophore biosynthetic process, peptide formation|activation of siderophore anabolism|up regulation of siderophore formation|up regulation of siderophore biosynthetic process|up regulation of siderophore biosynthesis|positive regulation of siderophore formation|up regulation of siderochrome biosynthetic process|up regulation of siderochrome biosynthesis|activation of siderophore synthesis|positive regulation of siderochrome biosynthesis|positive regulation of siderochrome biosynthetic process|up-regulation of siderophore anabolism|upregulation of siderophore biosynthetic process, peptide modification|activation of siderophore formation|up regulation of siderophore biosynthetic process, peptide formation|activation of siderochrome biosynthetic process|up-regulation of siderophore synthesis|activation of siderochrome biosynthesis|upregulation of siderophore biosynthesis|upregulation of siderophore biosynthetic process|positive regulation of siderophore biosynthetic process, peptide formation|up-regulation of siderophore formation|upregulation of siderophore anabolism|up-regulation of siderophore biosynthetic process, peptide modification|up-regulation of siderochrome biosynthesis|activation of siderophore biosynthetic process, peptide formation|up-regulation of siderochrome biosynthetic process|upregulation of siderophore synthesis Any process that activates or increases the frequency, rate or extent of siderophore biosynthetic process. GO:1900701 regulation of orcinol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900701 regulation of orcinol anabolism|regulation of orcinol synthesis|regulation of orcinol formation|regulation of orcinol biosynthesis Any process that modulates the frequency, rate or extent of orcinol biosynthetic process. GO:1900700 positive regulation of o-orsellinic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900700 up-regulation of o-orsellinic acid formation|upregulation of o-orsellinic acid anabolism|upregulation of o-orsellinic acid synthesis|upregulation of o-orsellinic acid biosynthetic process|upregulation of o-orsellinic acid biosynthesis|upregulation of o-orsellinic acid formation|up regulation of o-orsellinic acid anabolism|positive regulation of o-orsellinic acid anabolism|up regulation of o-orsellinic acid synthesis|up-regulation of o-orsellinic acid biosynthetic process|up-regulation of o-orsellinic acid biosynthesis|positive regulation of o-orsellinic acid synthesis|activation of o-orsellinic acid biosynthetic process|activation of o-orsellinic acid anabolism|up regulation of o-orsellinic acid formation|positive regulation of o-orsellinic acid formation|activation of o-orsellinic acid synthesis|activation of o-orsellinic acid biosynthesis|up-regulation of o-orsellinic acid anabolism|activation of o-orsellinic acid formation|positive regulation of o-orsellinic acid biosynthesis|up-regulation of o-orsellinic acid synthesis|up regulation of o-orsellinic acid biosynthetic process|up regulation of o-orsellinic acid biosynthesis Any process that activates or increases the frequency, rate or extent of o-orsellinic acid biosynthetic process. GO:1900703 positive regulation of orcinol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900703 positive regulation of orcinol formation|upregulation of orcinol biosynthetic process|upregulation of orcinol biosynthesis|activation of orcinol synthesis|up-regulation of orcinol anabolism|activation of orcinol formation|up-regulation of orcinol synthesis|up-regulation of orcinol biosynthetic process|activation of orcinol biosynthetic process|up-regulation of orcinol biosynthesis|up-regulation of orcinol formation|upregulation of orcinol anabolism|activation of orcinol biosynthesis|upregulation of orcinol synthesis|upregulation of orcinol formation|positive regulation of orcinol biosynthesis|up regulation of orcinol anabolism|up regulation of orcinol biosynthesis|up regulation of orcinol biosynthetic process|positive regulation of orcinol anabolism|up regulation of orcinol synthesis|positive regulation of orcinol synthesis|activation of orcinol anabolism|up regulation of orcinol formation Any process that activates or increases the frequency, rate or extent of orcinol biosynthetic process. GO:0022600 digestive system process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022600 A physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. GO:1900702 negative regulation of orcinol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900702 inhibition of orcinol biosynthetic process|negative regulation of orcinol synthesis|down-regulation of orcinol synthesis|down-regulation of orcinol formation|negative regulation of orcinol formation|inhibition of orcinol biosynthesis|inhibition of orcinol anabolism|inhibition of orcinol synthesis|inhibition of orcinol formation|down regulation of orcinol anabolism|down-regulation of orcinol biosynthetic process|down-regulation of orcinol biosynthesis|negative regulation of orcinol biosynthesis|down regulation of orcinol synthesis|downregulation of orcinol anabolism|down regulation of orcinol formation|downregulation of orcinol synthesis|downregulation of orcinol biosynthesis|downregulation of orcinol biosynthetic process|downregulation of orcinol formation|down-regulation of orcinol anabolism|negative regulation of orcinol anabolism|down regulation of orcinol biosynthesis|down regulation of orcinol biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of orcinol biosynthetic process. GO:0046635 positive regulation of alpha-beta T cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046635 positive regulation of alpha-beta T-lymphocyte activation|upregulation of alpha-beta T cell activation|positive regulation of alpha-beta T-cell activation|stimulation of alpha-beta T cell activation|up-regulation of alpha-beta T cell activation|activation of alpha-beta T cell activation|positive regulation of alpha-beta T lymphocyte activation|up regulation of alpha-beta T cell activation Any process that activates or increases the frequency, rate or extent of alpha-beta T cell activation. GO:0046634 regulation of alpha-beta T cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046634 regulation of alpha-beta T-lymphocyte activation|regulation of alpha-beta T-cell activation|regulation of alpha-beta T lymphocyte activation Any process that modulates the frequency, rate or extent of alpha-beta T cell activation. CHEBI:142940 dihexadecanoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142940 GO:0046633 alpha-beta T cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046633 alpha-beta T lymphocyte proliferation|alpha-beta T-cell proliferation|alpha-beta T-lymphocyte proliferation The expansion of an alpha-beta T cell population by cell division. GO:0046632 alpha-beta T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046632 alpha-beta T cell development|alpha-beta T lymphocyte differentiation|alpha-beta T-cell differentiation|alpha-beta T-lymphocyte differentiation The process in which a precursor cell type acquires the specialized features of an alpha-beta T cell. An alpha-beta T cell is a T cell that expresses an alpha-beta T cell receptor complex. GO:0046631 alpha-beta T cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046631 alpha-beta T lymphocyte activation|alpha-beta T-lymphocyte activation|alpha-beta T-cell activation The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. GO:0046630 gamma-delta T cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046630 gamma-delta T-cell proliferation|gamma-delta T-lymphocyte proliferation|gamma-delta T lymphocyte proliferation The expansion of a gamma-delta T cell population by cell division. GO:0022609 multicellular organism adhesion to substrate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022609 The attachment of a multicellular organism to a surface or material. GO:0046639 negative regulation of alpha-beta T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046639 negative regulation of alpha-beta T cell development|down-regulation of alpha-beta T cell differentiation|negative regulation of alpha-beta T lymphocyte differentiation|inhibition of alpha-beta T cell differentiation|negative regulation of alpha-beta T-cell differentiation|down regulation of alpha-beta T cell differentiation|negative regulation of alpha-beta T-lymphocyte differentiation|downregulation of alpha-beta T cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell differentiation. GO:0046638 positive regulation of alpha-beta T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046638 activation of alpha-beta T cell differentiation|positive regulation of alpha-beta T cell development|stimulation of alpha-beta T cell differentiation|positive regulation of alpha-beta T lymphocyte differentiation|up-regulation of alpha-beta T cell differentiation|positive regulation of alpha-beta T-cell differentiation|upregulation of alpha-beta T cell differentiation|positive regulation of alpha-beta T-lymphocyte differentiation|up regulation of alpha-beta T cell differentiation Any process that activates or increases the frequency, rate or extent of alpha-beta T cell differentiation. GO:0046637 regulation of alpha-beta T cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046637 regulation of alpha-beta T-cell differentiation|regulation of alpha-beta T-lymphocyte differentiation|regulation of alpha-beta T cell development|regulation of alpha-beta T lymphocyte differentiation Any process that modulates the frequency, rate or extent of alpha-beta T cell differentiation. GO:0046636 negative regulation of alpha-beta T cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046636 down regulation of alpha-beta T cell activation|negative regulation of alpha-beta T-cell activation|inhibition of alpha-beta T cell activation|negative regulation of alpha-beta T lymphocyte activation|down-regulation of alpha-beta T cell activation|negative regulation of alpha-beta T-lymphocyte activation|downregulation of alpha-beta T cell activation Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell activation. GO:0022602 ovulation cycle process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022602 estrous cycle process|menstrual cycle process A process involved in the sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years. GO:0022601 menstrual cycle phase biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0022601 The progression of physiological phases, occurring in the endometrium during the menstrual cycle that recur at regular intervals during the reproductive years. The menstrual cycle is an ovulation cycle where the endometrium is shed if pregnancy does not occur. GO:0022604 regulation of cell morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022604 regulation of cell shape and cell size|negative regulation of cell shape and cell size|positive regulation of cell shape and cell size Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized. GO:0022603 regulation of anatomical structure morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022603 regulation of morphogenesis Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis. GO:1900709 positive regulation of tensidol A biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900709 up regulation of tensidol A synthesis|positive regulation of tensidol A formation|up-regulation of tensidol A biosynthetic process|up-regulation of tensidol A biosynthesis|up regulation of tensidol A formation|upregulation of tensidol A anabolism|upregulation of tensidol A synthesis|upregulation of tensidol A biosynthetic process|upregulation of tensidol A biosynthesis|upregulation of tensidol A formation|up-regulation of tensidol A anabolism|up-regulation of tensidol A synthesis|activation of tensidol A anabolism|up regulation of tensidol A biosynthetic process|up regulation of tensidol A biosynthesis|up-regulation of tensidol A formation|activation of tensidol A biosynthetic process|positive regulation of tensidol A biosynthesis|activation of tensidol A synthesis|positive regulation of tensidol A anabolism|up regulation of tensidol A anabolism|activation of tensidol A formation|activation of tensidol A biosynthesis|positive regulation of tensidol A synthesis Any process that activates or increases the frequency, rate or extent of tensidol A biosynthetic process. GO:0022606 establishment of proximal/distal cell polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022606 The specification and formation of the polarity of a cell along its proximal/distal axis. GO:1900708 negative regulation of tensidol A biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900708 downregulation of tensidol A anabolism|inhibition of tensidol A biosynthetic process|down regulation of tensidol A anabolism|downregulation of tensidol A synthesis|downregulation of tensidol A formation|down regulation of tensidol A synthesis|inhibition of tensidol A biosynthesis|inhibition of tensidol A anabolism|down regulation of tensidol A formation|inhibition of tensidol A synthesis|down regulation of tensidol A biosynthesis|down regulation of tensidol A biosynthetic process|inhibition of tensidol A formation|downregulation of tensidol A biosynthetic process|downregulation of tensidol A biosynthesis|negative regulation of tensidol A anabolism|down-regulation of tensidol A anabolism|negative regulation of tensidol A synthesis|down-regulation of tensidol A synthesis|down-regulation of tensidol A biosynthetic process|down-regulation of tensidol A biosynthesis|negative regulation of tensidol A biosynthesis|negative regulation of tensidol A formation|down-regulation of tensidol A formation Any process that stops, prevents or reduces the frequency, rate or extent of tensidol A biosynthetic process. GO:0022605 mammalian oogenesis stage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022605 mammalian oogenesis process A reproductive process that is a step in the formation and maturation of an ovum or female gamete from a primordial female germ cell. GO:0022608 multicellular organism adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022608 The attachment of a multicellular organism to a substrate or other organism. GO:0022607 cellular component assembly biolink:BiologicalProcess go-plus goslim_chembl|goslim_pir|goslim_generic http://purl.obolibrary.org/obo/GO_0022607 cell structure assembly|cellular component assembly at cellular level The aggregation, arrangement and bonding together of a cellular component. GO:1900716 regulation of violaceol II biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900716 regulation of violaceol II biosynthesis|regulation of violaceol II anabolism|regulation of violaceol II synthesis|regulation of violaceol II formation Any process that modulates the frequency, rate or extent of violaceol II biosynthetic process. GO:1900715 positive regulation of violaceol I biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900715 up-regulation of violaceol I synthesis|up-regulation of violaceol I formation|upregulation of violaceol I anabolism|upregulation of violaceol I biosynthetic process|upregulation of violaceol I biosynthesis|upregulation of violaceol I synthesis|upregulation of violaceol I formation|up regulation of violaceol I anabolism|activation of violaceol I biosynthetic process|up-regulation of violaceol I biosynthesis|up-regulation of violaceol I biosynthetic process|positive regulation of violaceol I anabolism|up regulation of violaceol I synthesis|positive regulation of violaceol I synthesis|activation of violaceol I biosynthesis|up regulation of violaceol I formation|activation of violaceol I anabolism|positive regulation of violaceol I formation|activation of violaceol I synthesis|positive regulation of violaceol I biosynthesis|up-regulation of violaceol I anabolism|up regulation of violaceol I biosynthesis|up regulation of violaceol I biosynthetic process|activation of violaceol I formation Any process that activates or increases the frequency, rate or extent of violaceol I biosynthetic process. SO:0001055 transcriptional_cis_regulatory_region biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0001055 transcription-control region|transcriptional cis regulatory region|INSDC_qualifier:transcriptional_cis_regulatory_region|INSDC_feature:regulatory A regulatory_region that modulates the transcription of a gene or genes. GO:1900718 positive regulation of violaceol II biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900718 up-regulation of violaceol II synthesis|activation of violaceol II anabolism|up-regulation of violaceol II formation|up regulation of violaceol II biosynthesis|up regulation of violaceol II biosynthetic process|activation of violaceol II synthesis|activation of violaceol II biosynthetic process|positive regulation of violaceol II anabolism|positive regulation of violaceol II biosynthesis|up regulation of violaceol II anabolism|activation of violaceol II formation|positive regulation of violaceol II synthesis|activation of violaceol II biosynthesis|up regulation of violaceol II synthesis|positive regulation of violaceol II formation|up regulation of violaceol II formation|up-regulation of violaceol II biosynthetic process|up-regulation of violaceol II biosynthesis|upregulation of violaceol II anabolism|upregulation of violaceol II synthesis|upregulation of violaceol II formation|upregulation of violaceol II biosynthetic process|upregulation of violaceol II biosynthesis|up-regulation of violaceol II anabolism Any process that activates or increases the frequency, rate or extent of violaceol II biosynthetic process. GO:1900717 negative regulation of violaceol II biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900717 downregulation of violaceol II biosynthetic process|downregulation of violaceol II biosynthesis|down-regulation of violaceol II anabolism|negative regulation of violaceol II anabolism|down-regulation of violaceol II synthesis|negative regulation of violaceol II synthesis|down-regulation of violaceol II formation|negative regulation of violaceol II formation|negative regulation of violaceol II biosynthesis|down-regulation of violaceol II biosynthesis|down-regulation of violaceol II biosynthetic process|downregulation of violaceol II anabolism|downregulation of violaceol II synthesis|down regulation of violaceol II anabolism|inhibition of violaceol II biosynthetic process|downregulation of violaceol II formation|down regulation of violaceol II synthesis|inhibition of violaceol II biosynthesis|down regulation of violaceol II formation|inhibition of violaceol II anabolism|inhibition of violaceol II synthesis|down regulation of violaceol II biosynthetic process|down regulation of violaceol II biosynthesis|inhibition of violaceol II formation Any process that stops, prevents or reduces the frequency, rate or extent of violaceol II biosynthetic process. GO:1900712 positive regulation of tensidol B biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900712 activation of tensidol B anabolism|up-regulation of tensidol B formation|up regulation of tensidol B biosynthesis|up regulation of tensidol B biosynthetic process|activation of tensidol B synthesis|positive regulation of tensidol B anabolism|positive regulation of tensidol B biosynthesis|activation of tensidol B biosynthetic process|activation of tensidol B formation|up regulation of tensidol B anabolism|positive regulation of tensidol B synthesis|activation of tensidol B biosynthesis|up regulation of tensidol B synthesis|positive regulation of tensidol B formation|up regulation of tensidol B formation|up-regulation of tensidol B biosynthesis|up-regulation of tensidol B biosynthetic process|upregulation of tensidol B anabolism|upregulation of tensidol B synthesis|upregulation of tensidol B formation|upregulation of tensidol B biosynthesis|upregulation of tensidol B biosynthetic process|up-regulation of tensidol B anabolism|up-regulation of tensidol B synthesis Any process that activates or increases the frequency, rate or extent of tensidol B biosynthetic process. GO:1900711 negative regulation of tensidol B biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900711 downregulation of tensidol B biosynthesis|downregulation of tensidol B biosynthetic process|negative regulation of tensidol B anabolism|down-regulation of tensidol B anabolism|negative regulation of tensidol B synthesis|down-regulation of tensidol B synthesis|negative regulation of tensidol B formation|down-regulation of tensidol B formation|down-regulation of tensidol B biosynthetic process|down-regulation of tensidol B biosynthesis|negative regulation of tensidol B biosynthesis|downregulation of tensidol B anabolism|down regulation of tensidol B anabolism|downregulation of tensidol B synthesis|inhibition of tensidol B biosynthetic process|downregulation of tensidol B formation|down regulation of tensidol B synthesis|inhibition of tensidol B anabolism|inhibition of tensidol B biosynthesis|down regulation of tensidol B formation|inhibition of tensidol B synthesis|down regulation of tensidol B biosynthetic process|inhibition of tensidol B formation|down regulation of tensidol B biosynthesis Any process that stops, prevents or reduces the frequency, rate or extent of tensidol B biosynthetic process. GO:1900714 negative regulation of violaceol I biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900714 downregulation of violaceol I biosynthetic process|downregulation of violaceol I biosynthesis|inhibition of violaceol I anabolism|down regulation of violaceol I biosynthesis|down regulation of violaceol I biosynthetic process|inhibition of violaceol I synthesis|inhibition of violaceol I biosynthetic process|inhibition of violaceol I formation|down regulation of violaceol I anabolism|inhibition of violaceol I biosynthesis|downregulation of violaceol I anabolism|down regulation of violaceol I synthesis|down regulation of violaceol I formation|downregulation of violaceol I synthesis|downregulation of violaceol I formation|negative regulation of violaceol I anabolism|down-regulation of violaceol I anabolism|down-regulation of violaceol I biosynthesis|down-regulation of violaceol I biosynthetic process|negative regulation of violaceol I biosynthesis|negative regulation of violaceol I synthesis|down-regulation of violaceol I synthesis|negative regulation of violaceol I formation|down-regulation of violaceol I formation Any process that stops, prevents or reduces the frequency, rate or extent of violaceol I biosynthetic process. GO:1900713 regulation of violaceol I biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900713 regulation of violaceol I biosynthesis|regulation of violaceol I anabolism|regulation of violaceol I synthesis|regulation of violaceol I formation Any process that modulates the frequency, rate or extent of violaceol I biosynthetic process. OIO:hasSynonymType has_synonym_type biolink:OntologyClass go-plus http://www.geneontology.org/formats/oboInOwl#hasSynonymType GO:0046646 regulation of gamma-delta T cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046646 regulation of gamma-delta T-cell proliferation|regulation of gamma-delta T-lymphocyte proliferation|regulation of gamma-delta T lymphocyte proliferation Any process that modulates the frequency, rate or extent of gamma-delta T cell proliferation. GO:0046645 positive regulation of gamma-delta T cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046645 positive regulation of gamma-delta T lymphocyte activation|up regulation of gamma-delta T cell activation|activation of gamma-delta T cell activation|stimulation of gamma-delta T cell activation|positive regulation of gamma-delta T-lymphocyte activation|up-regulation of gamma-delta T cell activation|positive regulation of gamma-delta T-cell activation|upregulation of gamma-delta T cell activation Any process that activates or increases the frequency, rate or extent of gamma-delta T cell activation. GO:1900710 regulation of tensidol B biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900710 regulation of tensidol B anabolism|regulation of tensidol B synthesis|regulation of tensidol B formation|regulation of tensidol B biosynthesis Any process that modulates the frequency, rate or extent of tensidol B biosynthetic process. GO:0046644 negative regulation of gamma-delta T cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046644 downregulation of gamma-delta T cell activation|negative regulation of gamma-delta T lymphocyte activation|down-regulation of gamma-delta T cell activation|inhibition of gamma-delta T cell activation|negative regulation of gamma-delta T-lymphocyte activation|negative regulation of gamma-delta T-cell activation|down regulation of gamma-delta T cell activation Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell activation. CHEBI:21291 L-fuconate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_21291 GO:0046643 regulation of gamma-delta T cell activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046643 regulation of gamma-delta T-lymphocyte activation|regulation of gamma-delta T-cell activation|regulation of gamma-delta T lymphocyte activation Any process that modulates the frequency, rate or extent of gamma-delta T cell activation. GO:0046642 negative regulation of alpha-beta T cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046642 downregulation of alpha-beta T cell proliferation|negative regulation of alpha-beta T-lymphocyte proliferation|down-regulation of alpha-beta T cell proliferation|negative regulation of alpha-beta T lymphocyte proliferation|inhibition of alpha-beta T cell proliferation|negative regulation of alpha-beta T-cell proliferation|down regulation of alpha-beta T cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell proliferation. GO:0046641 positive regulation of alpha-beta T cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046641 up regulation of alpha-beta T cell proliferation|activation of alpha-beta T cell proliferation|stimulation of alpha-beta T cell proliferation|positive regulation of alpha-beta T lymphocyte proliferation|up-regulation of alpha-beta T cell proliferation|positive regulation of alpha-beta T-cell proliferation|upregulation of alpha-beta T cell proliferation|positive regulation of alpha-beta T-lymphocyte proliferation Any process that activates or increases the frequency, rate or extent of alpha-beta T cell proliferation. GO:0046640 regulation of alpha-beta T cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046640 regulation of alpha-beta T lymphocyte proliferation|regulation of alpha-beta T-cell proliferation|regulation of alpha-beta T-lymphocyte proliferation Any process that modulates the frequency, rate or extent of alpha-beta T cell proliferation. CHEBI:142938 gentamycin 2''-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_142938 GO:0071609 chemokine (C-C motif) ligand 5 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0071609 Regulated upon Activation, Normal T-cell Expressed, and Secreted production|CCL5 production|RANTES production The appearance of chemokine (C-C motif) ligand 5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0071608 macrophage inflammatory protein-1 alpha production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0071608 macrophage inflammatory protein production|chemokine (C-C motif) ligand 3 production|CCL3 production|MIP-1a production The appearance of macrophage inflammatory protein 1 alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0071607 macrophage inflammatory protein-1 gamma production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0071607 chemokine (C-C motif) ligand 9 production|CCL9 production|MIP-1g production The appearance of macrophage inflammatory protein-1 gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0071606 chemokine (C-C motif) ligand 4 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0071606 macrophage inflammatory protein production|CCL4 production|MIP-1b production The appearance of chemokine (C-C motif) ligand 4 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0071605 monocyte chemotactic protein-1 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0071605 CCL2 production|MCP-1 production The appearance of monocyte chemotactic protein-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0046649 lymphocyte activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046649 A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor. CHEBI:166988 glycerophosphoglycerophosphoglycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_166988 GO:0071604 transforming growth factor beta production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071604 TGF-B production|transforming growth factor-beta production|TGFbeta production|transforming growth factor-beta secretion|TGFb production|TGF-beta production The appearance of any member of the transforming growth factor-beta family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Transforming growth factor-beta family members include TGF-B1, TGF-B2, and TGF-B3. GO:0046648 positive regulation of gamma-delta T cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046648 up regulation of gamma-delta T cell proliferation|positive regulation of gamma-delta T lymphocyte proliferation|upregulation of gamma-delta T cell proliferation|positive regulation of gamma-delta T-cell proliferation|stimulation of gamma-delta T cell proliferation|up-regulation of gamma-delta T cell proliferation|activation of gamma-delta T cell proliferation|positive regulation of gamma-delta T-lymphocyte proliferation Any process that activates or increases the frequency, rate or extent of gamma-delta T cell proliferation. GO:0046647 negative regulation of gamma-delta T cell proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046647 down-regulation of gamma-delta T cell proliferation|negative regulation of gamma-delta T lymphocyte proliferation|downregulation of gamma-delta T cell proliferation|down regulation of gamma-delta T cell proliferation|inhibition of gamma-delta T cell proliferation|negative regulation of gamma-delta T-cell proliferation|negative regulation of gamma-delta T-lymphocyte proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell proliferation. GO:0071603 endothelial cell-cell adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071603 The attachment of an endothelial cell to another endothelial cell via adhesion molecules. GO:0071602 phytosphingosine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071602 phytosphingosine biosynthesis|phytosphingosine anabolism|phytosphingosine synthesis|phytosphingosine formation The chemical reactions and pathways resulting in the formation of phytosphingosine, (2S,3S,4R)-2-aminooctadecane-1,3,4-triol. UBERON:0002203 vasculature of eye biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002203 eye vasculature|optic vasculature|eye vascular network|ocular blood vessel|ocular vasculature|vascular network of eye Vasculature that is part of the eye region. UBERON:0002202 submucosa of trachea biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002202 submucous layer of trachea|tracheal submucosa|trachea submucosa|submucosa of windpipe|windpipe submucosa A submucosa that is part of a trachea. GO:0071601 sphere organelle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071601 A nuclear body that is found in the germinal vesicles of amphibian oocytes, and consist of three major parts: a remarkably spherical body about 5-10 pm in diameter, smaller spherical or nearly spherical granules on the surface, and inclusions of various sizes that strongly resemble the surface granules. The parts of the sphere organelle have distinct compositions, including splicing snRNAs and proteins. GO:0071600 otic vesicle morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071600 The process in which the anatomical structures of the otic vesicle are generated and organized. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear. UBERON:0002204 musculoskeletal system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002204 musculo-skeletal system Anatomical system that consists of the muscular and skeletal systems. GO:1900719 regulation of uterine smooth muscle relaxation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900719 regulation of smooth muscle relaxation of the uterus Any process that modulates the frequency, rate or extent of uterine smooth muscle relaxation. UBERON:0002201 vasculature of trunk biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002201 vasculature of torso|torso vascular network|trunk vascular network|vascular network of trunk|vascular network of torso|trunk vasculature|torso vasculature A vasculature that is part of a trunk [Automatically generated definition]. UBERON:0002200 vasculature of head biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002200 vasculature of adult head|head vascular network|adult head vascular network|adult head vasculature|vascular network of adult head|head vasculature|cranial vasculature|vascular network of head Vasculature that is part of a head [Automatically generated definition]. GO:1900727 osmoregulated periplasmic glucan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900727 osmoregulated periplasmic glucan anabolism|osmoregulated periplasmic glucan biosynthesis|osmoregulated periplasmic glucan synthesis|osmoregulated periplasmic glucan formation The chemical reactions and pathways resulting in the formation of osmoregulated periplasmic glucan. GO:1900726 osmoregulated periplasmic glucan catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900726 osmoregulated periplasmic glucan catabolism|osmoregulated periplasmic glucan degradation|osmoregulated periplasmic glucan breakdown The chemical reactions and pathways resulting in the breakdown of osmoregulated periplasmic glucan. GO:1900729 regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900729 regulation of inhibition of adenylate cyclase activity by opioid receptor signalling pathway|regulation of opioid receptor-mediated adenylate cyclase inhibition|regulation of inhibition of adenylate cyclase activity by opioid receptor signaling pathway|regulation of inhibition of adenylate cyclase activity by opioid receptor Any process that modulates the frequency, rate or extent of adenylate cyclase-inhibiting opioid receptor signaling pathway. GO:1900728 cardiac neural crest cell delamination involved in outflow tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900728 Any cardiac neural crest cell delamination that is involved in outflow tract morphogenesis. GO:1900723 negative regulation of protein adenylylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900723 down regulation of protein adenylylation|downregulation of protein amino acid adenylylation|downregulation of protein adenylylation|down regulation of protein amino acid adenylylation|downregulation of protein AMPylation|inhibition of protein adenylation|down regulation of protein AMPylation|inhibition of protein amino acid adenylylation|down regulation of protein adenylation|down-regulation of protein adenylylation|inhibition of protein AMPylation|downregulation of protein adenylation|inhibition of protein adenylylation|down-regulation of protein amino acid adenylylation|negative regulation of protein amino acid adenylylation|down-regulation of protein adenylation|negative regulation of protein adenylation|down-regulation of protein AMPylation|negative regulation of protein AMPylation Any process that stops, prevents or reduces the frequency, rate or extent of protein adenylylation. GO:1900722 regulation of protein adenylylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900722 regulation of protein amino acid adenylylation|regulation of protein AMPylation|regulation of protein adenylation Any process that modulates the frequency, rate or extent of protein adenylylation. GO:1900725 osmoregulated periplasmic glucan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900725 osmoregulated periplasmic glucan metabolism The chemical reactions and pathways involving osmoregulated periplasmic glucan. GO:1900724 positive regulation of protein adenylylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900724 positive regulation of protein AMPylation|up-regulation of protein adenylation|up regulation of protein AMPylation|up regulation of protein adenylylation|upregulation of protein amino acid adenylylation|activation of protein adenylylation|upregulation of protein adenylation|upregulation of protein AMPylation|up-regulation of protein amino acid adenylylation|up regulation of protein adenylation|up-regulation of protein adenylylation|up-regulation of protein AMPylation|positive regulation of protein adenylation|activation of protein amino acid adenylylation|activation of protein AMPylation|activation of protein adenylation|positive regulation of protein amino acid adenylylation|upregulation of protein adenylylation|up regulation of protein amino acid adenylylation Any process that activates or increases the frequency, rate or extent of protein adenylylation. GO:0046657 folic acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046657 vitamin M catabolism|folic acid catabolism|folate catabolic process|vitamin B9 catabolism|folic acid degradation|vitamin B9 catabolic process|folic acid breakdown|folate catabolism|vitamin M catabolic process The chemical reactions and pathways resulting in the breakdown of folic acid, pteroylglutamic acid. GO:0046656 folic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046656 Wikipedia:Folic_acid|MetaCyc:FOLSYN-PWY folic acid synthesis|folic acid formation|vitamin M biosynthesis|vitamin M biosynthetic process|folic acid biosynthesis|vitamin B9 biosynthetic process|vitamin B9 biosynthesis|folate biosynthetic process|folate biosynthesis|folic acid anabolism The chemical reactions and pathways resulting in the formation of folic acid, pteroylglutamic acid. GO:1900721 positive regulation of uterine smooth muscle relaxation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900721 up-regulation of uterine smooth muscle relaxation|activation of uterine smooth muscle relaxation|upregulation of smooth muscle relaxation of the uterus|up-regulation of smooth muscle relaxation of the uterus|up regulation of uterine smooth muscle relaxation|activation of smooth muscle relaxation of the uterus|positive regulation of smooth muscle relaxation of the uterus|up regulation of smooth muscle relaxation of the uterus|upregulation of uterine smooth muscle relaxation Any process that activates or increases the frequency, rate or extent of uterine smooth muscle relaxation. GO:0046655 folic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046655 folate metabolic process|vitamin M metabolism|folic acid metabolism|vitamin B9 metabolic process|vitamin B9 metabolism|vitamin M metabolic process|folate metabolism The chemical reactions and pathways involving folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines. GO:1900720 negative regulation of uterine smooth muscle relaxation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900720 inhibition of smooth muscle relaxation of the uterus|down-regulation of uterine smooth muscle relaxation|downregulation of uterine smooth muscle relaxation|negative regulation of smooth muscle relaxation of the uterus|down-regulation of smooth muscle relaxation of the uterus|down regulation of uterine smooth muscle relaxation|inhibition of uterine smooth muscle relaxation|downregulation of smooth muscle relaxation of the uterus|down regulation of smooth muscle relaxation of the uterus Any process that stops, prevents or reduces the frequency, rate or extent of uterine smooth muscle relaxation. GO:0046654 tetrahydrofolate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046654 MetaCyc:FOLSYN-PWY tetrahydrofolate anabolism|tetrahydrofolate synthesis|tetrahydrofolate biosynthesis|tetrahydrofolate formation The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group. GO:0046653 tetrahydrofolate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046653 tetrahydrofolate metabolism The chemical reactions and pathways involving tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group. CHEBI:45257 ribostamycin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_45257 GO:0046652 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046652 GO:0046651 lymphocyte proliferation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046651 The expansion of a lymphocyte population by cell division. GO:0046650 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046650 CHEBI:59894 (Z)-3-aminoacrylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59894 CHEBI:59893 (Z)-3-aminoacrylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59893 CHEBI:59892 (Z)-3-aminoperacrylic acid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59892 CHEBI:59891 ureidoacrylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59891 CHEBI:59890 ureidoacrylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59890 CHEBI:142921 3-phenylprop-2-enal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142921 GO:0046659 digestive hormone activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046659 secretin The action characteristic of a hormone that takes part in the digestion process. GO:0046658 anchored component of plasma membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0046658 plasma membrane, GPI-anchored|anchored to plasma membrane The component of the plasma membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group, that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. CHEBI:59899 3-nitropropanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59899 CHEBI:59898 3-iodo-L-tyrosine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59898 CHEBI:59897 EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59897 CHEBI:59896 glutathione amide disulfide dizwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59896 CHEBI:59895 glutathione amide zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59895 GO:1900738 positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900738 activation of phospholipase C-activating G-protein coupled receptor signaling pathway|up-regulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|activation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|upregulation of phospholipase C-activating dopamine receptor signaling pathway|activation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|upregulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|up-regulation of PLC-activating GPCR signaling pathway|activation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|up-regulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|up regulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|up-regulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|positive regulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|positive regulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|up regulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|up-regulation of phospholipase C-activating G-protein coupled receptor signaling pathway|up-regulation of phospholipase C-activating dopamine receptor signaling pathway|positive regulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|activation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|up-regulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|upregulation of PLC-activating GPCR signaling pathway|up regulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|activation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway|upregulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|activation of phospholipase C-activating dopamine receptor signaling pathway|positive regulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|up regulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|upregulation of phospholipase C-activating G-protein coupled receptor signaling pathway|activation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|upregulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|up-regulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|positive regulation of phospholipase C-activating dopamine receptor signaling pathway|up regulation of PLC-activating GPCR signaling pathway|upregulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|positive regulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|up regulation of phospholipase C-activating dopamine receptor signaling pathway|positive regulation of PLC-activating GPCR signaling pathway|up regulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|up regulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|positive regulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|upregulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|up-regulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|up regulation of phospholipase C-activating G-protein coupled receptor signaling pathway|upregulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|activation of PLC-activating GPCR signaling pathway Any process that activates or increases the frequency, rate or extent of phospholipase C-activating G protein-coupled receptor signaling pathway. GO:0046660 female sex differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046660 The establishment of the sex of a female organism by physical differentiation. GO:1900737 negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900737 negative regulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|down-regulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|inhibition of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|down regulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|down regulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|down-regulation of phospholipase C-activating G-protein coupled receptor signaling pathway|down-regulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|downregulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|negative regulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|inhibition of phospholipase C-activating dopamine receptor signaling pathway|down-regulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|negative regulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|inhibition of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|inhibition of PLC-activating GPCR signaling pathway|inhibition of phospholipase C-activating G-protein coupled receptor signaling pathway|negative regulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|inhibition of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|down-regulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|negative regulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|down-regulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|downregulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|downregulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|down regulation of PLC-activating GPCR signaling pathway|negative regulation of phospholipase C-activating dopamine receptor signaling pathway|down regulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|down-regulation of phospholipase C-activating dopamine receptor signaling pathway|down regulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway|down regulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|downregulation of PLC-activating GPCR signaling pathway|down-regulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|negative regulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|downregulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|down regulation of phospholipase C-activating G-protein coupled receptor signaling pathway|downregulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|inhibition of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|down regulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|inhibition of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|downregulation of phospholipase C-activating G-protein coupled receptor signaling pathway|downregulation of phospholipase C-activating dopamine receptor signaling pathway|inhibition of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|downregulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|down-regulation of PLC-activating GPCR signaling pathway|negative regulation of PLC-activating GPCR signaling pathway|down regulation of phospholipase C-activating dopamine receptor signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase C-activating G protein-coupled receptor signaling pathway. CHEBI:45240 1,2-di-O-myristoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_45240 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900739 regulation of protein insertion into mitochondrion membrane during induction of apoptosis|regulation of protein insertion into mitochondrial membrane during induction of apoptosis|regulation of insertion of proteins into mitochondrial membranes during the induction of apoptosis|regulation of protein insertion into mitochondrial membrane involved in induction of apoptosis Any process that modulates the frequency, rate or extent of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway. GO:1900734 positive regulation of polyketide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900734 upregulation of polyketide anabolism|upregulation of polyketide biosynthetic process|upregulation of polyketide biosynthesis|upregulation of polyketide synthesis|upregulation of polyketide formation|up-regulation of polyketide anabolism|up regulation of polyketide biosynthetic process|up regulation of polyketide biosynthesis|activation of polyketide biosynthetic process|positive regulation of polyketide biosynthesis|up-regulation of polyketide synthesis|activation of polyketide anabolism|up-regulation of polyketide formation|activation of polyketide biosynthesis|activation of polyketide synthesis|positive regulation of polyketide anabolism|up regulation of polyketide anabolism|activation of polyketide formation|up-regulation of polyketide biosynthesis|up-regulation of polyketide biosynthetic process|positive regulation of polyketide synthesis|up regulation of polyketide synthesis|positive regulation of polyketide formation|up regulation of polyketide formation Any process that activates or increases the frequency, rate or extent of polyketide biosynthetic process. GO:1900733 negative regulation of polyketide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900733 downregulation of polyketide formation|down regulation of polyketide synthesis|down regulation of polyketide biosynthesis|down regulation of polyketide biosynthetic process|down regulation of polyketide formation|inhibition of polyketide anabolism|downregulation of polyketide biosynthetic process|downregulation of polyketide biosynthesis|inhibition of polyketide synthesis|inhibition of polyketide formation|down-regulation of polyketide anabolism|negative regulation of polyketide biosynthesis|down-regulation of polyketide biosynthesis|negative regulation of polyketide anabolism|down-regulation of polyketide biosynthetic process|down-regulation of polyketide synthesis|negative regulation of polyketide synthesis|inhibition of polyketide biosynthetic process|down-regulation of polyketide formation|negative regulation of polyketide formation|downregulation of polyketide anabolism|inhibition of polyketide biosynthesis|down regulation of polyketide anabolism|downregulation of polyketide synthesis Any process that stops, prevents or reduces the frequency, rate or extent of polyketide biosynthetic process. GO:1900736 regulation of phospholipase C-activating G protein-coupled receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900736 regulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|regulation of phospholipase C-activating G-protein coupled receptor signaling pathway|regulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|regulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|regulation of PLC-activating GPCR signaling pathway|regulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|regulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|regulation of phospholipase C-activating dopamine receptor signaling pathway|regulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating) Any process that modulates the frequency, rate or extent of phospholipase C-activating G protein-coupled receptor signaling pathway. GO:1900735 positive regulation of flocculation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900735 upregulation of flocculation|up-regulation of flocculation via cell wall protein-carbohydrate interaction|up-regulation of flocculation|activation of flocculation|upregulation of flocculation via cell wall protein-carbohydrate interaction|positive regulation of flocculation via cell wall protein-carbohydrate interaction|up regulation of flocculation|up regulation of flocculation via cell wall protein-carbohydrate interaction|activation of flocculation via cell wall protein-carbohydrate interaction Any process that activates or increases the frequency, rate or extent of flocculation. GO:1900730 negative regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900730 negative regulation of inhibition of adenylate cyclase activity by opioid receptor signalling pathway|negative regulation of inhibition of adenylate cyclase activity by opioid receptor signaling pathway|down-regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway|inhibition of opioid receptor-mediated adenylate cyclase inhibition|downregulation of adenylate cyclase-inhibiting opioid receptor signaling pathway|down regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway|inhibition of adenylate cyclase-inhibiting opioid receptor signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase-inhibiting opioid receptor signaling pathway. GO:0046668 regulation of retinal cell programmed cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046668 regulation of retinal programmed cell death Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the retina. GO:0046667 compound eye retinal cell programmed cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046667 Programmed cell death that occurs in the retina to remove excess cells between ommatidia, thus resulting in a hexagonal lattice, precise with respect to cell number and position surrounding each ommatidium. GO:1900732 regulation of polyketide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900732 regulation of polyketide synthesis|regulation of polyketide formation|regulation of polyketide biosynthesis|regulation of polyketide anabolism Any process that modulates the frequency, rate or extent of polyketide biosynthetic process. GO:0046666 retinal cell programmed cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046666 programmed cell death, retinal cells|retinal programmed cell death|retina cell programmed cell death|programmed cell death, retina cells|retina programmed cell death Programmed cell death that occurs in the developing retina. GO:1900731 positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900731 activation of opioid receptor-mediated adenylate cyclase inhibition|up regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway|upregulation of adenylate cyclase-inhibiting opioid receptor signaling pathway|activation of adenylate cyclase-inhibiting opioid receptor signaling pathway Any process that activates or increases the frequency, rate or extent of adenylate cyclase-inhibiting opioid receptor signaling pathway. GO:0046665 amnioserosa maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046665 Maintenance of the amnioserosa, an epithelium that occupies a hole in the embryonic dorsal epidermis. GO:0046664 dorsal closure, amnioserosa morphology change biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046664 The changes that occur during dorsal closure of the shape and structure of the amnioserosa, an epithelium that occupies the dorsal side of the embryo. GO:0046663 dorsal closure, leading edge cell differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046663 The process in which a relatively unspecialized cell acquires specialized features of a leading edge cell, the dorsal-most cells of the epidermis that migrates during dorsal closure. GO:0046662 regulation of oviposition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046662 regulation of post-mating oviposition Any process that modulates the frequency, rate or extent of the deposition of eggs, either fertilized or not, upon a surface or into a medium. GO:0046661 male sex differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046661 The establishment of the sex of a male organism by physical differentiation. CHEBI:59881 keto-D-fructuronate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59881 GO:0071629 cytoplasm protein quality control by the ubiquitin-proteasome system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071629 cytoplasm-associated proteasomal ubiquitin-dependent protein catabolism|cytoplasm-associated proteasomal ubiquitin-dependent protein degradation|cytoplasm-associated proteasomal ubiquitin-dependent protein breakdown|ubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome The chemical reactions and pathways resulting in the breakdown of misfolded proteins in the cytoplasm, which are targeted to cytoplasmic proteasomes for degradation. GO:0071628 intrinsic component of fungal-type vacuolar membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071628 The component of a fungal-type vacuole membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. GO:0071627 integral component of fungal-type vacuolar membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071627 integral to fungal-type vacuolar membrane The component of the fungal-type vacuole membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. GO:0071626 mastication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071626 chewing The process of biting and mashing food with the teeth prior to swallowing. GO:0071625 vocalization behavior biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071625 vocalisation behaviour The behavior in which an organism produces sounds by a mechanism involving its respiratory system. GO:0046669 regulation of compound eye retinal cell programmed cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046669 regulation of retinal cell programmed cell death Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the compound eye retina. GO:0071624 positive regulation of granulocyte chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071624 Any process that increases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus. GO:0071623 negative regulation of granulocyte chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071623 Any process that decreases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus. GO:0071622 regulation of granulocyte chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071622 Any process that modulates the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus. CHEBI:59889 ureidoperacrylic acid biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59889 GO:0071621 granulocyte chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071621 The movement of a granulocyte in response to an external stimulus. CHEBI:59888 gamma-aminobutyric acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59888 GO:0071620 phosphorylation of RNA polymerase II C-terminal domain serine 5 residues biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071620 The process of introducing a phosphate group onto a serine residue at position 5 within the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II. Typically, phosphorylation of serine 5 (Ser5) occurs near the 5' ends of genes. It is generally still observed in the middle of genes, overlapping with phosphorylation of serine 2, but is generally not present at the 3' ends of genes. In vivo, Ser5 phosphorylation occurs primarily through the action of TFIIH (KIN28 in S. cerevisiae, CKD7 in metazoans). CHEBI:59887 2-imino-3-(7-chloroindol-3-yl)propionate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59887 CHEBI:59885 XTP(3-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59885 CHEBI:59884 XDP(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59884 GO:0046671 negative regulation of retinal cell programmed cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046671 down regulation of retinal programmed cell death|downregulation of retinal programmed cell death|negative regulation of retinal programmed cell death|down-regulation of retinal programmed cell death|inhibition of retinal programmed cell death Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the retina. SO:0001067 polypeptide_motif biolink:SequenceFeature go-plus biosapiens http://purl.obolibrary.org/obo/SO_0001067 polypeptide motif|motif A sequence motif is a short (up to 20 amino acids) region of biological interest. Such motifs, although they are too short to constitute functional domains, share sequence similarities and are conserved in different proteins. They display a common function (protein-binding, subcellular location etc.). GO:1900749 (R)-carnitine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900749 Levocarnitine transport|Carnitor transport|Vitamin BT transport|L-Carnitine transport|Carnitine transport|C7H15NO3 transport|Carnicor transport|Carnitene transport|(3R)-3-hydroxy-4-(trimethylammonio)butanoate transport|(-)-Carnitine transport|(R)-Carnitine transport|(-)-L-Carnitine transport The directed movement of a (R)-carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0046670 positive regulation of retinal cell programmed cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046670 positive regulation of retinal programmed cell death|up regulation of retinal programmed cell death|activation of retinal programmed cell death|stimulation of retinal programmed cell death|up-regulation of retinal programmed cell death|upregulation of retinal programmed cell death Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the retina. GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900748 up-regulation of vascular endothelial growth factor signalling pathway|positive regulation of VEGF-activated signaling pathway|up regulation of VEGF-activated signaling pathway|up-regulation of VEGF signaling|up regulation of vascular endothelial growth factor signaling pathway|upregulation of vascular endothelial growth factor signalling pathway|activation of VEGF signaling|upregulation of VEGF-activated signaling pathway|upregulation of vascular endothelial growth factor signaling pathway|positive regulation of VEGF signaling|up regulation of vascular endothelial growth factor signalling pathway|up regulation of VEGF signaling|positive regulation of vascular endothelial growth factor signalling pathway|up-regulation of VEGF-activated signaling pathway|up-regulation of vascular endothelial growth factor signaling pathway|activation of vascular endothelial growth factor signalling pathway|activation of vascular endothelial growth factor signaling pathway|upregulation of VEGF signaling|activation of VEGF-activated signaling pathway Any process that activates or increases the frequency, rate or extent of vascular endothelial growth factor signaling pathway. CHEBI:45230 (R)-dihydrolipoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_45230 CHEBI:21285 erythro-4-hydroxy-L-glutamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21285 CHEBI:21288 L-erythrose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_21288 GO:1900745 positive regulation of p38MAPK cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900745 up-regulation of p38MAPK cascade|up-regulation of p38 MAPK cascade|up regulation of p38 cascade|positive regulation of p38 cascade|activation of p38 MAPK cascade|activation of p38 cascade|upregulation of p38MAPK cascade|positive regulation of p38 MAPK cascade|up regulation of p38 MAPK cascade|up-regulation of p38 cascade|up regulation of p38MAPK cascade|activation of p38MAPK cascade|upregulation of p38 MAPK cascade|upregulation of p38 cascade Any process that activates or increases the frequency, rate or extent of p38MAPK cascade. GO:1900744 regulation of p38MAPK cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900744 regulation of p38 MAPK cascade|regulation of p38 cascade Any process that modulates the frequency, rate or extent of p38MAPK cascade. GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900747 down-regulation of VEGF-activated signaling pathway|negative regulation of VEGF-activated signaling pathway|inhibition of VEGF signaling|down-regulation of vascular endothelial growth factor signaling pathway|inhibition of vascular endothelial growth factor signalling pathway|downregulation of VEGF-activated signaling pathway|downregulation of vascular endothelial growth factor signaling pathway|down regulation of VEGF-activated signaling pathway|down regulation of vascular endothelial growth factor signalling pathway|down-regulation of VEGF signaling|negative regulation of VEGF signaling|down regulation of vascular endothelial growth factor signaling pathway|inhibition of vascular endothelial growth factor signaling pathway|downregulation of vascular endothelial growth factor signalling pathway|inhibition of VEGF-activated signaling pathway|downregulation of VEGF signaling|down-regulation of vascular endothelial growth factor signalling pathway|negative regulation of vascular endothelial growth factor signalling pathway|down regulation of VEGF signaling Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial growth factor signaling pathway. GO:1900746 regulation of vascular endothelial growth factor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900746 regulation of VEGF-activated signaling pathway|regulation of vascular endothelial growth factor signalling pathway|regulation of VEGF signaling Any process that modulates the frequency, rate or extent of vascular endothelial growth factor signaling pathway. GO:1900741 regulation of filamentous growth of a population of unicellular organisms in response to pH biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900741 Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to pH. GO:0046679 response to streptomycin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046679 streptomycin susceptibility/resistance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a streptomycin stimulus. Streptomycin is a commonly used antibiotic in cell culture media which acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome. GO:1900740 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900740 upregulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway|positive regulation of protein insertion into mitochondrial membrane involved in induction of apoptosis|up regulation of protein insertion into mitochondrial membrane during induction of apoptosis|up-regulation of protein insertion into mitochondrion membrane during induction of apoptosis|up regulation of protein insertion into mitochondrial membrane involved in induction of apoptosis|upregulation of insertion of proteins into mitochondrial membranes during the induction of apoptosis|positive regulation of protein insertion into mitochondrial membrane during induction of apoptosis|activation of protein insertion into mitochondrial membrane during induction of apoptosis|up regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway|activation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway|upregulation of protein insertion into mitochondrion membrane during induction of apoptosis|upregulation of protein insertion into mitochondrial membrane involved in induction of apoptosis|up-regulation of insertion of proteins into mitochondrial membranes during the induction of apoptosis|up-regulation of protein insertion into mitochondrial membrane during induction of apoptosis|activation of insertion of proteins into mitochondrial membranes during the induction of apoptosis|up regulation of protein insertion into mitochondrion membrane during induction of apoptosis|up-regulation of protein insertion into mitochondrial membrane involved in induction of apoptosis|up-regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway|positive regulation of insertion of proteins into mitochondrial membranes during the induction of apoptosis|upregulation of protein insertion into mitochondrial membrane during induction of apoptosis|positive regulation of protein insertion into mitochondrion membrane during induction of apoptosis|up regulation of insertion of proteins into mitochondrial membranes during the induction of apoptosis|activation of protein insertion into mitochondrial membrane involved in induction of apoptosis|activation of protein insertion into mitochondrion membrane during induction of apoptosis Any process that activates or increases the frequency, rate or extent of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway. GO:0046678 response to bacteriocin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046678 bacteriocin susceptibility/resistance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacteriocin stimulus. A bacteriocin is a protein substance released by certain bacteria that kills but does not lyse closely related strains of bacteria. Specific bacteriocins attach to specific receptors on cell walls and induce specific metabolic block, e.g. cessation of nucleic acid or protein synthesis of oxidative phosphorylation. GO:1900743 positive regulation of filamentous growth of a population of unicellular organisms in response to pH biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900743 up regulation of filamentous growth of a population of unicellular organisms in response to pH|activation of filamentous growth of a population of unicellular organisms in response to pH|up-regulation of filamentous growth of a population of unicellular organisms in response to pH|upregulation of filamentous growth of a population of unicellular organisms in response to pH Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to pH. GO:0046677 response to antibiotic biolink:BiologicalProcess go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0046677 antibiotic susceptibility/resistance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms. GO:1900742 negative regulation of filamentous growth of a population of unicellular organisms in response to pH biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900742 downregulation of filamentous growth of a population of unicellular organisms in response to pH|down-regulation of filamentous growth of a population of unicellular organisms in response to pH|inhibition of filamentous growth of a population of unicellular organisms in response to pH|down regulation of filamentous growth of a population of unicellular organisms in response to pH Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to pH. GO:0046676 negative regulation of insulin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046676 down regulation of insulin secretion|downregulation of insulin secretion|down-regulation of insulin secretion|inhibition of insulin secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of insulin. GO:0046675 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046675 CHEBI:21282 (3S,5S)-3,5-diaminohexanoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21282 GO:0046674 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046674 GO:0046673 negative regulation of compound eye retinal cell programmed cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046673 negative regulation of retina cell programmed cell death|downregulation of retinal cell programmed cell death|down regulation of retinal cell programmed cell death|inhibition of retinal cell programmed cell death|negative regulation of retinal cell programmed cell death|down-regulation of retinal cell programmed cell death Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the compound eye retina. GO:0046672 positive regulation of compound eye retinal cell programmed cell death biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046672 positive regulation of retinal cell programmed cell death|up regulation of retinal cell programmed cell death|upregulation of retinal cell programmed cell death|up-regulation of retinal cell programmed cell death|stimulation of retinal cell programmed cell death|activation of retinal cell programmed cell death Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the compound eye retina. CHEBI:59872 heptaketide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59872 CHEBI:59871 D-alpha-amino acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59871 GO:0071619 phosphorylation of RNA polymerase II C-terminal domain serine 2 residues biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071619 The process of introducing a phosphate group onto a serine residue at position 2 within the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II. Typically, phosphorylation of serine 2 (Ser2) occurs subsequent to phosphorylation of serine 5 and is thus seen in the middle and 3' ends of genes. In vivo, Ser2 phosphorylation is primarily performed by CTDK-I in S. cerevisiae or CDK9 in metazoans. GO:0071618 lysophosphatidylethanolamine acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071618 Catalysis of the transfer of acyl groups from an acyl-CoA to lysophosphatidylethanolamine. GO:0071617 lysophospholipid acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071617 Catalysis of the transfer of acyl groups from an acyl-CoA to a lysophospholipid. GO:0071616 acyl-CoA biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071616 acyl-CoA anabolism|acyl-CoA synthesis|acyl-CoA biosynthesis|acyl-CoA formation The chemical reactions and pathways resulting in the formation of acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with an acyl group. GO:0071615 obsolete oxidative deethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071615 OBSOLETE. The process of removing one or more ethyl groups from a molecule, involving the oxidation (i.e. electron loss) of one or more atoms in the substrate. GO:0071614 linoleic acid epoxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071614 linoleic acid monooxygenase activity Catalysis of an NADPH- and oxygen-dependent reaction that converts linoleic acid to a cis-epoxyoctadecenoic acid. GO:0071613 granzyme B production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0071613 The appearance of granzyme B due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0071612 IP-10 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0071612 CXCL10 production|chemokine (C-C motif) ligand 10 production The appearance of IP-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. CHEBI:59879 (24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-en-26-oyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59879 GO:0071611 granulocyte colony-stimulating factor production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0071611 pluripoietin production|G-CSF production|filgrastim production|granulocyte colony stimulating factor production|CSF3 production|colony stimulating factor 3 (granulocyte) production|lenograstim production The appearance of granulocyte colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0071610 chemokine (C-C motif) ligand 1 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0071610 TCA-3 production|T cell activation 3 production|CCL1 production The appearance of chemokine (C-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. CHEBI:59876 N-acyl-D-alpha-amino acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59876 CHEBI:59874 N-acyl-L-alpha-amino acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59874 GO:0032039 integrator complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032039 A protein complex that stably associates with the C-terminus of RNA polymerase II and mediates 3'-end processing of small nuclear RNAs generated by RNA polymerase II. CHEBI:84824 aromatic L-alpha-amino acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84824 CHEBI:84822 1-octadecanoyl-2-[(9Z,12Z)-octadecadienoyl]-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84822 GO:0007079 mitotic chromosome movement towards spindle pole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007079 mitotic chromosome movement to spindle pole|mitotic chromosome movement|sister chromosome movement towards spindle pole during mitosis|chromosome migration to spindle pole during mitosis|chromosome movement towards spindle pole during mitosis|mitotic sister chromosome movement towards spindle pole The cell cycle process in which the directed movement of chromosomes from the center of the spindle towards the spindle poles occurs. This mediates by the shortening of microtubules attached to the chromosomes, during mitosis. GO:0007078 lamin depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007078 The cell cycle process in which lamin is depolymerized. GO:0007077 mitotic nuclear envelope disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007077 mitotic nuclear envelope breakdown|local NEB|NEB|nuclear envelope breakdown|mitotic nuclear envelope catabolism|mitotic nuclear envelope degradation The mitotic cell cycle process in which the controlled partial or complete breakdown of the nuclear envelope during occurs during mitosis. GO:0007076 mitotic chromosome condensation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007076 The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells. GO:0007075 positive regulation of transcription involved in exit from mitosis, from RNA polymerase III promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007075 activation of transcription on exit from mitosis, from RNA polymerase III promoter|activation of transcription on exit from mitosis, from Pol III promoter Any process that increases the frequency, rate or extent of transcription from an RNA polymerase III promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place. GO:0032030 myosin I light chain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032030 Interacting selectively and non-covalently with a light chain of a myosin I complex. GO:0007085 obsolete nuclear membrane vesicle binding to chromatin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007085 nuclear membrane vesicle binding to chromatin OBSOLETE. (Was not defined before being made obsolete). GO:0007084 mitotic nuclear envelope reassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007084 nuclear envelope repair|nuclear envelope resealing The mitotic cell cycle process involving ESCRTIII that results in reformation of the nuclear envelope after mitotic nuclear division. In organisms undergoing closed mitosis this involves resealing or 'repair' of the nuclear envelope in the nuclear bridge. CHEBI:60860 6-ammonio-5-oxocyclohex-2-ene-1-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60860 CHEBI:60863 (1S,6R)-6-ammonio-5-oxocyclohex-2-ene-1-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60863 GO:0007083 mitotic chromosome decondensation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007083 The cell cycle process in which chromosome structure is altered from the condensed form taken on during mitosis to the relaxed disperse form held in resting cells. CHEBI:60862 (1R,6S)-6-ammonio-5-oxocyclohex-2-ene-1-carboxylate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60862 GO:0007082 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007082 GO:0007081 obsolete mitotic sister-chromatid adhesion release biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007081 mitotic sister-chromatid adhesion release OBSOLETE. (Was not defined before being made obsolete). GO:0007080 mitotic metaphase plate congression biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007080 The cell cycle process in which chromosomes are aligned at the metaphase plate, a plane halfway between the poles of the mitotic spindle, during mitosis. GO:0032038 myosin II heavy chain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032038 Interacting selectively and non-covalently with a heavy chain of a myosin II complex. CHEBI:60869 (3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60869 GO:0032037 myosin I heavy chain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032037 Interacting selectively and non-covalently with a heavy chain of a myosin I complex. GO:0032036 myosin heavy chain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032036 Interacting selectively and non-covalently with a heavy chain of a myosin complex. GO:0032035 myosin II tail binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032035 Interacting selectively and non-covalently with the tail region of a myosin II heavy chain. GO:0032034 myosin II head/neck binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032034 Interacting selectively and non-covalently with the head/neck region of a myosin II heavy chain. GO:0032033 myosin II light chain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032033 Interacting selectively and non-covalently with a light chain of a myosin II complex. GO:0032032 myosin I tail binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032032 Interacting selectively and non-covalently with the tail region of a myosin I heavy chain. GO:0032031 myosin I head/neck binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032031 Interacting selectively and non-covalently with the head/neck region of a myosin I heavy chain. SO:0001089 post_translationally_modified_region biolink:SequenceFeature go-plus biosapiens http://purl.obolibrary.org/obo/SO_0001089 http://en.wikipedia.org/wiki/Post_translational_modification post_translational_modification|modified residue|mod_res A region where a transformation occurs in a protein after it has been synthesized. This which may regulate, stabilize, crosslink or introduce new chemical functionalities in the protein. CHEBI:84839 1,2-di-[(9Z)-octadecenoyl]-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84839 GO:0032029 myosin tail binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032029 Interacting selectively and non-covalently with the tail region of a myosin heavy chain. CHEBI:84838 O-isobutyryl-L-carnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84838 GO:0032028 myosin head/neck binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032028 Interacting selectively and non-covalently with the head/neck region of a myosin heavy chain. CHEBI:84836 1,2-di-octadecenoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84836 CHEBI:84834 O-hexanoyl-L-carnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84834 GO:0007089 traversing start control point of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007089 A cell cycle process by which a cell commits to entering S phase via a positive feedback mechanism between the regulation of transcription and G1 CDK activity. GO:0007088 regulation of mitotic nuclear division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007088 regulation of mitosis Any process that modulates the frequency, rate or extent of mitosis. GO:0007087 mitotic nuclear pore complex reassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007087 The cell cycle process in which nuclear pore complexes reform during mitotic cell division. CHEBI:60870 aza fatty acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60870 GO:0007086 vesicle fusion with nuclear membrane involved in mitotic nuclear envelope reassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007086 The cell cycle process that results in the joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the nucleus, and contributes to mitotic nuclear envelope reassembly. GO:0007096 regulation of exit from mitosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007096 Any process involved in the progression from anaphase/telophase to G1 that is associated with a conversion from high to low mitotic CDK activity. GO:0007095 mitotic G2 DNA damage checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007095 mitotic cell cycle G2/M transition DNA damage checkpoint A mitotic cell cycle checkpoint that detects and negatively regulates progression through the G2/M transition of the cell cycle in response to DNA damage. GO:0007094 mitotic spindle assembly checkpoint biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007094 mitotic checkpoint|mitotic cell cycle spindle assembly checkpoint|SAC-independent checkpoint|Dma1-dependent checkpoint|Mad2-dependent checkpoint A cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle. CHEBI:60874 phenylacetylglycine(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60874 GO:0007093 mitotic cell cycle checkpoint biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0007093 mitotic checkpoint A cell cycle checkpoint that ensures accurate chromosome replication and segregation by preventing progression through a mitotic cell cycle until conditions are suitable for the cell to proceed to the next stage. CHEBI:60873 2',3'-cyclic UMP(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60873 GO:0007092 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007092 GO:0007091 metaphase/anaphase transition of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007091 mitotic metaphase/anaphase transition|metaphase/anaphase transition by anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process The cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin. CHEBI:60875 3'-CMP(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60875 GO:0007090 obsolete regulation of S phase of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007090 regulation of S-phase of mitotic cell cycle|regulation of S phase of mitotic cell cycle OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of the progression through the S phase of the mitotic cell cycle. CHEBI:60878 3-geranyl-4-hydroxybenzoate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60878 CHEBI:60877 2',3'-cyclic CMP(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60877 GO:0032027 myosin light chain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032027 Interacting selectively and non-covalently with a light chain of a myosin complex. GO:0032026 response to magnesium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032026 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus. CHEBI:60879 2',3'-cyclic AMP(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60879 GO:0032025 response to cobalt ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032025 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt ion stimulus. GO:0032024 positive regulation of insulin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032024 upregulation of insulin secretion|up regulation of insulin secretion|activation of insulin secretion|stimulation of insulin secretion|up-regulation of insulin secretion Any process that activates or increases the frequency, rate or extent of the regulated release of insulin. GO:0032023 trypsinogen activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032023 cleavage of trypsinogen to trypsin The proteolytic processing of trypsinogen to the active form, trypsin. GO:0032022 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032022 GO:0032021 NELF complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032021 negative elongation factor complex A complex of five proteins, designated NELF-A, -B, -C, -D, and -E in human, that can physically associate with RNP polymerase II to induce transcriptional pausing. GO:0032020 ISG15-protein conjugation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032020 The covalent addition to a protein of ISG15, a ubiquitin-like protein. CHEBI:11909 3beta-hydroxy-5alpha-pregnan-20-one biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_11909 GO:0032019 mitochondrial cloud biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032019 mitochondrial aggregate|Balbiani body A prominent mass in the cytoplasm of previtellogenic oocytes. The cloud contains both mitochondria and electron-dense granulofibrillar material (GFM) and is the source of germinal granule material. GO:0032018 2-methylbutanol:NADP oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032018 2-methylbutanal reductase (NADP) activity|2-methylbutyraldehyde reductase (NADP) activity Catalysis of the reaction: 2-methylbutanol + NADP+ = 2-methylbutanal + NADPH + H+. GO:0032017 positive regulation of Ran protein signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032017 up regulation of Ran protein signal transduction|activation of Ran protein signal transduction|stimulation of Ran protein signal transduction|up-regulation of Ran protein signal transduction|upregulation of Ran protein signal transduction Any process that activates or increases the frequency, rate or extent of Ran protein signal transduction. CHEBI:84847 2,6-dimethylheptanoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84847 CHEBI:11901 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_11901 GO:0007059 chromosome segregation biolink:BiologicalProcess go-plus goslim_chembl|goslim_yeast|goslim_pir|goslim_generic http://purl.obolibrary.org/obo/GO_0007059 Wikipedia:Chromosome_segregation chromosome division|chromosome transmission The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles. GO:0007058 spindle assembly involved in female meiosis II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007058 female meiosis II spindle assembly The aggregation, arrangement and bonding together of a set of components to form the spindle during meiosis II of a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster. GO:0007057 spindle assembly involved in female meiosis I biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007057 female meiosis I spindle assembly The aggregation, arrangement and bonding together of a set of components to form the spindle during meiosis I of a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster. CHEBI:84843 (R)-2,6-dimethylheptanoylcarnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84843 GO:0007056 spindle assembly involved in female meiosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007056 female meiotic spindle assembly The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster. CHEBI:84842 (R)-3-hydroxybutyrylcarnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84842 GO:0007055 spindle assembly involved in male meiosis II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007055 male meiosis II spindle assembly The formation of the spindle during meiosis II of a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster. GO:0007054 spindle assembly involved in male meiosis I biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007054 male meiosis I spindle assembly The formation of the spindle during meiosis I of a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster. CHEBI:84841 (R)-acetoacetylcarnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84841 CHEBI:84840 (R)-2-methylbutyrylcarnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84840 GO:0007053 spindle assembly involved in male meiosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007053 The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster. CHEBI:60880 3'-AMP(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60880 GO:0007063 regulation of sister chromatid cohesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007063 Any process that modulates the frequency, rate or extent of sister chromatid cohesion. GO:0007062 sister chromatid cohesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007062 sister chromatid alignment|coheson-mediated DNA tethering The cell cycle process in which the sister chromatids of a replicated chromosome become tethered to each other. CHEBI:60885 (2E,4E)-6-(2-aminophenyl)-2-hydroxy-6-oxohexa-2,4-dienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60885 GO:0007061 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007061 GO:0007060 male meiosis chromosome segregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007060 The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a male. CHEBI:60887 3-hydroxy-D-aspartic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60887 CHEBI:60886 (2E)-2-hydroxypenta-2,4-dienoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60886 GO:0032016 negative regulation of Ran protein signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032016 down regulation of Ran protein signal transduction|downregulation of Ran protein signal transduction|down-regulation of Ran protein signal transduction|inhibition of Ran protein signal transduction Any process that stops, prevents, or reduces the frequency, rate or extent of Ran protein signal transduction. GO:0032015 regulation of Ran protein signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032015 Any process that modulates the frequency, rate or extent of Ran protein signal transduction. GO:0032014 positive regulation of ARF protein signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032014 upregulation of ARF protein signal transduction|up regulation of ARF protein signal transduction|activation of ARF protein signal transduction|stimulation of ARF protein signal transduction|up-regulation of ARF protein signal transduction Any process that activates or increases the frequency, rate or extent of ARF protein signal transduction. GO:0032013 negative regulation of ARF protein signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032013 down regulation of ARF protein signal transduction|downregulation of ARF protein signal transduction|down-regulation of ARF protein signal transduction|inhibition of ARF protein signal transduction Any process that stops, prevents, or reduces the frequency, rate or extent of ARF protein signal transduction. GO:0032012 regulation of ARF protein signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032012 Any process that modulates the frequency, rate or extent of ARF protein signal transduction. GO:0032011 ARF protein signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032011 A series of molecular signals within the cell that are mediated by a member of the ARF family of proteins switching to a GTP-bound active state. GO:0032010 phagolysosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032010 Wikipedia:Phagolysosome late phagocytic vesicle|late phagosome A membrane-bounded intracellular vesicle formed by maturation of an early phagosome following the ingestion of particulate material by phagocytosis; during maturation, phagosomes acquire markers of late endosomes and lysosomes. GO:0032009 early phagosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032009 early phagocytic vesicle A membrane-bounded intracellular vesicle as initially formed upon the ingestion of particulate material by phagocytosis. GO:0032008 positive regulation of TOR signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032008 up-regulation of TOR signaling pathway|upregulation of TOR signaling pathway|positive regulation of target of rapamycin signaling pathway|positive regulation of TOR signalling pathway|up regulation of TOR signaling pathway|positive regulation of TOR signaling pathway|activation of TOR signaling pathway|positive regulation of target of rapamycin signalling pathway|stimulation of TOR signaling pathway|positive regulation of TOR signaling cascade Any process that activates or increases the frequency, rate or extent of TOR signaling. GO:0032007 negative regulation of TOR signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032007 negative regulation of TOR signaling cascade|inhibition of TOR signaling pathway|negative regulation of TOR signalling pathway|down regulation of TOR signaling pathway|negative regulation of target of rapamycin signaling pathway|downregulation of TOR signaling pathway|negative regulation of target of rapamycin signalling pathway|down-regulation of TOR signaling pathway|negative regulation of TOR signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of TOR signaling. GO:0032006 regulation of TOR signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032006 regulation of target of rapamycin signaling pathway|regulation of TOR signaling pathway|regulation of TOR signalling pathway|regulation of TOR signaling cascade|regulation of target of rapamycin signalling pathway Any process that modulates the frequency, rate or extent of TOR signaling. GO:0007069 obsolete negative regulation of transcription from RNA polymerase I promoter during mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007069 down-regulation of transcription from RNA polymerase I promoter during mitosis|negative regulation of transcription from RNA polymerase I promoter, mitotic|inhibition of transcription from RNA polymerase I promoter during mitosis|negative regulation of transcription from Pol I promoter during mitosis|mitotic repression of transcription from Pol I promoter|down regulation of transcription from RNA polymerase I promoter during mitosis|downregulation of transcription from RNA polymerase I promoter during mitosis OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase I promoter that occurs during the mitotic cell cycle. GO:0007068 obsolete negative regulation of transcription during mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007068 mitotic repression of transcription|downregulation of transcription during mitosis|down regulation of transcription during mitosis|inhibition of transcription during mitosis|down-regulation of transcription during mitosis|negative regulation of transcription, mitotic OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription that occurs during the mitotic cell cycle. GO:0007067 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007067 CHEBI:84854 2-hydroxyheptadecanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84854 GO:0007066 female meiosis sister chromatid cohesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007066 The joining of the sister chromatids of a replicated chromosome along the entire length of the chromosome that occurs during meiosis in a female. GO:0007065 male meiosis sister chromatid cohesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007065 The joining of the sister chromatids of a replicated chromosome along the entire length of the chromosome that occurs during meiosis in a male. CHEBI:60892 polyamino carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60892 GO:0007064 mitotic sister chromatid cohesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007064 The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the entire length of the chromosome, from their formation in S phase through metaphase during a mitotic cell cycle. This cohesion cycle is critical for high fidelity chromosome transmission. CHEBI:60894 (3S)-3-hydroxy-D-aspartate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60894 CHEBI:84850 L-selenohomocysteine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84850 GO:0007074 positive regulation of transcription involved in exit from mitosis, from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007074 activation of transcription on exit from mitosis, from Pol II promoter|activation of transcription on exit from mitosis, from RNA polymerase II promoter Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place. GO:0007073 positive regulation of transcription involved in exit from mitosis, from RNA polymerase I promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007073 activation of transcription on exit from mitosis, from Pol I promoter|activation of transcription on exit from mitosis, from RNA polymerase I promoter Any process that increases the frequency, rate or extent of transcription from an RNA polymerase I promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place. CHEBI:60893 (3S)-3-hydroxy-D-aspartic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60893 GO:0007072 positive regulation of transcription involved in exit from mitosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007072 activation of transcription on exit from mitosis Any process that increases the frequency, rate or extent of transcription as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place. GO:0007071 obsolete negative regulation of transcription from RNA polymerase III promoter during mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007071 down regulation of transcription from RNA polymerase III promoter during mitosis|downregulation of transcription from RNA polymerase III promoter during mitosis|down-regulation of transcription from RNA polymerase III promoter during mitosis|negative regulation of transcription from RNA polymerase III promoter, mitotic|inhibition of transcription from RNA polymerase III promoter during mitosis|negative regulation of transcription from Pol III promoter during mitosis|mitotic repression of transcription from Pol III promoter OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase III promoter that occurs during the mitotic cell cycle. CHEBI:60895 D-alpha-amino acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60895 GO:0007070 obsolete negative regulation of transcription from RNA polymerase II promoter during mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007070 negative regulation of transcription from Pol II promoter during mitosis|down-regulation of transcription from RNA polymerase II promoter during mitosis|negative regulation of transcription from RNA polymerase II promoter, mitotic|mitotic repression of transcription from Pol II promoter|downregulation of transcription from RNA polymerase II promoter during mitosis|down regulation of transcription from RNA polymerase II promoter during mitosis|inhibition of transcription from RNA polymerase II promoter during mitosis OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter that occurs during the mitotic cell cycle. CHEBI:60898 (3R)-3-hydroxy-D-aspartate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60898 CHEBI:60897 (3R)-3-hydroxy-D-aspartic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60897 CHEBI:60899 ubiquinol-0 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60899 GO:0032005 signal transduction involved in positive regulation of conjugation with cellular fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032005 The series of molecular signals that bring about the relay, amplification or dampening of a signal generated in response to a cue, such as starvation or pheromone exposure, in organisms that undergo conjugation with cellular fusion. GO:0032004 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032004 GO:0032003 interleukin-28 receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032003 IL-28|interleukin-28 receptor ligand Interacting selectively and non-covalently with the interleukin-28 receptor. GO:0032002 interleukin-28 receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032002 IL-28 receptor complex A protein complex that binds interleukin-28 and interleukin-29. It is composed of an alpha and a beta receptor subunit (in human IFNLR1/IL28Ralpha & IL10RB) and either Interleukin-28 (IFNL2 or IFNL3) or Interleukin-29 (IFNL1). GO:0032001 1,4-alpha-glucan 6-alpha-glucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032001 EC:2.4.1.24|MetaCyc:2.4.1.24-RXN 1,4-alpha-D-glucan 6-alpha-D-glucosyltransferase activity|1,4-alpha-D-glucan:1,4-alpha-D-glucan(D-glucose) 6-alpha-D-glucosyltransferase activity|D-glucosyltransferase|oligoglucan-branching glycosyltransferase activity|T-enzyme Catalysis of the transfer an alpha-D-glucosyl residue in a (1->4)-alpha-D-glucan to the primary hydroxy group of glucose, free or combined in a (1->4)-alpha-D-glucan. GO:0032000 positive regulation of fatty acid beta-oxidation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032000 up-regulation of fatty acid beta-oxidation|upregulation of fatty acid beta-oxidation|up regulation of fatty acid beta-oxidation|activation of fatty acid beta-oxidation|stimulation of fatty acid beta-oxidation Any process that activates or increases the frequency, rate or extent of fatty acid beta-oxidation. GO:0007039 protein catabolic process in the vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007039 vacuolar protein catabolism|vacuolar protein degradation|vacuolar protein breakdown|vacuolar protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein in the vacuole, usually by the action of vacuolar proteases. GO:0007038 endocytosed protein transport to vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007038 delivery of endocytosed proteins to the vacuole The directed movement of proteins imported into a cell by endocytosis to the vacuole. GO:0007037 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007037 GO:0007036 vacuolar calcium ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007036 Any process involved in the maintenance of an internal steady state of calcium ions in the vacuole or between a vacuole and its surroundings. CHEBI:84866 (2S)-methylsuccinyl-CoA(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84866 GO:0007035 vacuolar acidification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007035 Any process that reduces the pH of the vacuole, measured by the concentration of the hydrogen ion. GO:0007034 vacuolar transport biolink:BiologicalProcess go-plus goslim_generic|goslim_chembl http://purl.obolibrary.org/obo/GO_0007034 The directed movement of substances into, out of or within a vacuole. GO:0007033 vacuole organization biolink:BiologicalProcess go-plus goslim_yeast|goslim_pir http://purl.obolibrary.org/obo/GO_0007033 vacuolar assembly|vacuole organization and biogenesis|vacuole organisation|vacuole biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole. GO:0007032 endosome organization biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0007032 endosome organization and biogenesis|endosome organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of endosomes. GO:0007031 peroxisome organization biolink:BiologicalProcess go-plus goslim_pombe|goslim_yeast|goslim_pir http://purl.obolibrary.org/obo/GO_0007031 peroxisome-assembly ATPase activity|peroxisome organization and biogenesis|peroxisome organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a peroxisome. A peroxisome is a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules. GO:0007041 lysosomal transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007041 The directed movement of substances into, out of or within a lysosome. GO:0007040 lysosome organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007040 lysosome organisation|lysosome organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases. CHEBI:166904 glycosyldiradylglycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_166904 CHEBI:166903 glycosylmonoradylglycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_166903 CHEBI:166902 noradrenaline(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_166902 CHEBI:70231 phenazine-1,6-dicarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70231 GO:0007049 cell cycle biolink:BiologicalProcess go-plus goslim_candida|goslim_agr|gocheck_do_not_manually_annotate|goslim_pir|goslim_plant|goslim_aspergillus|goslim_generic|goslim_flybase_ribbon|goslim_chembl http://purl.obolibrary.org/obo/GO_0007049 Wikipedia:Cell_cycle cell-division cycle The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. GO:0007048 obsolete oncogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007048 oncogenesis OBSOLETE. (Was not defined before being made obsolete). CHEBI:84879 nitroxyl biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84879 GO:0007047 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007047 GO:0007046 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007046 GO:0007045 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007045 GO:0007044 cell-substrate junction assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007044 cell-substrate adherens junction assembly The aggregation, arrangement and bonding together of a set of components to form a junction between a cell and its substrate. GO:0007043 cell-cell junction assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007043 intercellular junction assembly The aggregation, arrangement and bonding together of a set of components to form a junction between cells. GO:0007042 lysosomal lumen acidification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007042 lysosome pH reduction Any process that reduces the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion. GO:0007052 mitotic spindle organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007052 mitotic spindle organization and biogenesis in nucleus|mitotic spindle organisation in nucleus|spindle organization and biogenesis during mitosis|mitotic spindle stabilization|mitotic spindle organisation|spindle organization and biogenesis in nucleus during mitosis|mitotic spindle organization and biogenesis|mitotic spindle organization and biogenesis in cell nucleus|mitotic spindle organization in nucleus A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle. GO:0007051 spindle organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007051 spindle stabilization|spindle organization and biogenesis|spindle organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle, the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during DNA segregation and serves to move the duplicated chromosomes apart. GO:0007050 cell cycle arrest biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007050 termination of cell cycle|arrest of cell cycle progression|cessation of cell cycle A regulatory process that halts progression through the cell cycle during one of the normal phases (G1, S, G2, M). GO:0007019 microtubule depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007019 microtubule depolymerization during nuclear congression|microtubule shortening|microtubule catastrophe|microtubule disassembly The removal of tubulin heterodimers from one or both ends of a microtubule. GO:0007018 microtubule-based movement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007018 A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules. GO:0007017 microtubule-based process biolink:BiologicalProcess go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0007017 Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins. GO:0007016 obsolete cytoskeletal anchoring at plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007016 cytoskeletal anchoring activity OBSOLETE. A cytoskeleton organization process that directly or indirectly links cytoskeletal filaments to the plasma membrane. GO:0007015 actin filament organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007015 actin filament organisation|regulation of actin filament localization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking. GO:0007014 actin ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007014 indirect flight muscle actin ubiquitination The modification of actin by addition of ubiquitin groups. GO:0007013 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007013 GO:0007012 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007012 GO:0007011 obsolete regulation of cytoskeleton biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007011 regulation of cytoskeleton OBSOLETE. Any process that modulates the frequency, rate or extent of the organization, biogenesis or maintenance of the cytoskeleton. CHEBI:84886 GDP-alpha-D-mannuronate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84886 GO:0007010 cytoskeleton organization biolink:BiologicalProcess go-plus goslim_generic|goslim_chembl|goslim_yeast|goslim_candida|goslim_aspergillus http://purl.obolibrary.org/obo/GO_0007010 cytoskeletal regulator activity|cytoskeleton organisation|cytoskeletal organization and biogenesis|cytoskeleton organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures. CHEBI:84881 GDP-D-mannose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84881 CHEBI:84880 GDP-D-mannose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84880 GO:0007029 endoplasmic reticulum organization biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0007029 ER organisation|endoplasmic reticulum organisation|endoplasmic reticulum morphology|endoplasmic reticulum organization and biogenesis|ER organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum. GO:0007028 cytoplasm organization biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0007028 cytoplasm organisation|cytoplasm organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cytoplasm. The cytoplasm is all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. GO:0007027 negative regulation of axonemal microtubule depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007027 axonemal microtubule stabilization|negative regulation of microtubule depolymerization in axoneme Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of the specialized microtubules of the axoneme. GO:0007026 negative regulation of microtubule depolymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007026 microtubule stabilization|negative regulation of microtubule disassembly|negative regulation of microtubule catastrophe|down-regulation of microtubule depolymerization|downregulation of microtubule depolymerization|down regulation of microtubule depolymerization|inhibition of microtubule depolymerization|microtubule rescue Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol. GO:0007025 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007025 GO:0007024 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007024 CHEBI:84898 (R)-crotonylcarnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84898 GO:0007023 post-chaperonin tubulin folding pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007023 Completion of folding of alpha- and beta-tubulin; takes place subsequent to chaperonin-mediated partial folding; mediated by a complex of folding cofactors. GO:0007022 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007022 CHEBI:84897 nogalonate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84897 GO:0007021 tubulin complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007021 tubulin assembly|tubulin-specific chaperone activity|tubulin folding The aggregation and bonding together of alpha- and beta-tubulin to form a tubulin heterodimer. GO:0007020 microtubule nucleation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007020 Wikipedia:Microtubule_nucleation The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation). GO:0007030 Golgi organization biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0007030 Golgi organisation|Golgi organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus. CHEBI:35816 leprostatic drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35816 CHEBI:35818 coccidiostat biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35818 CHEBI:35819 branched-chain fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35819 CHEBI:35810 3-carboxy-3-hydroxypentanedioate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35810 CHEBI:35812 oxfendazole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35812 CHEBI:35811 2-endo-hydroxy-1,8-cineole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35811 GO:0071594 thymocyte aggregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071594 immature T cell aggregation|thymic lymphocyte aggregation|immature T-lymphocyte aggregation|immature T-cell aggregation|T cell precursor aggregation The adhesion of one thymocyte (an immature T cell) to one or more other thymocytes via adhesion molecules. GO:0071593 lymphocyte aggregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071593 The adhesion of one lymphocyte to one or more other lymphocytes via adhesion molecules. GO:0071592 nicotinic acid riboside biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071592 nicotinic acid riboside synthesis|nicotinic acid riboside formation|D-ribosylnicotinic acid biosynthetic process|nicotinic acid riboside biosynthesis|nicotinic acid riboside anabolism The chemical reactions and pathways resulting in the formation of nicotinic acid riboside, the product of the formation of a glycosidic bond between ribose and nicotinic acid. GO:0071591 nicotinic acid riboside metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071591 nicotinic acid riboside metabolism|D-ribosylnicotinic acid metabolic process The chemical reactions and pathways involving nicotinic acid riboside, the product of the formation of a glycosidic bond between ribose and nicotinic acid. GO:0071590 nicotinamide riboside biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071590 nicotinamide riboside biosynthesis|N-ribosylnicotinamide biosynthetic process|nicotinamide riboside anabolism|nicotinamide riboside synthesis|nicotinamide riboside formation The chemical reactions and pathways resulting in the formation of nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide. CHEBI:35825 mandelic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35825 CHEBI:35821 anticholesteremic drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35821 CHEBI:35820 antiprotozoal drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35820 GO:0071599 otic vesicle development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071599 The process whose specific outcome is the progression of the otic vesicle over time, from its formation to the mature structure. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear. GO:0071598 neuronal ribonucleoprotein granule biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071598 neuronal RNA granule|neuronal RNP granule A ribonucleoprotein complex that is found in the cytoplasm of axons and dendrites, and transports translationally silenced mRNAs to dendritic synapses, where they are released and translated in response to specific exogenous stimuli. GO:0071597 cellular birth scar biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071597 Crater-like ring of chitinous scar tissue located on the surface of the daughter cell, in budding fungi, at the site of separation from the mother cell. It is formed after the newly emerged daughter cell separates, thereby marking the site of cytokinesis and septation. GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071596 ubiquitin-dependent protein catabolism via the N-end rule pathway|ubiquitin-dependent protein degradation via the N-end rule pathway|ubiquitin-dependent protein breakdown via the N-end rule pathway The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the N-end rule pathway. In the N-end rule pathway, destabilizing N-terminal residues (N-degrons) in substrates are recognized by E3 ligases (N-recognins), whereupon the substrates are linked to ubiquitin and then delivered to the proteasome for degradation. GO:0071595 Nem1-Spo7 phosphatase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071595 A protein serine/threonine phosphatase complex that is involved in nuclear envelope organization, and contains proteins known in budding yeast as Nem1p and Spo7p. CHEBI:11867 3-oxo-5beta-cholanate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_11867 CHEBI:60801 guanyl deoxyribonucleotide residue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60801 CHEBI:60807 anaesthesia adjuvant biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60807 CHEBI:60809 adjuvant biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60809 CHEBI:35802 3-carboxy-2-(carboxymethyl)-2-hydroxypropanoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35802 CHEBI:35804 citrate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35804 CHEBI:35806 3,4-dicarboxy-3-hydroxybutanoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35806 CHEBI:35809 2-(carboxymethyl)-2-hydroxysuccinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35809 CHEBI:35808 citrate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35808 UBERON:0002294 biliary system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002294 biliary tract|biliary apparatus Organ system subdivision that consists of the organs and ducts that are involved in the production and transportation of bile. In most species this is the gallbladder and the bile ducts (biliary tree). UBERON:0002296 dorsal mesentery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002296 mesenterium dorsale commune|dorsal mesogastrium The mesentery that originates from the dorsal side of the peritoneal cavity[ZFA]. UBERON:0002290 choroid plexus of fourth ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002290 4th ventricle choroid plexus|fourth ventricle choroid plexus|fourth ventricle chorioid plexus of cerebral hemisphere|choroid plexus fourth ventricle|chorioid plexus of cerebral hemisphere of fourth ventricle|chorioid plexus of fourth ventricle Choroid plexus of the fourth ventricle CHEBI:35801 nitroso group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35801 UBERON:0002291 central canal of spinal cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002291 central canal, spinal cord/medulla|central canal|canalis centralis|spinal cord central canal|central canal of spinal cord|ventricle of spinal cord Spinal cord structure that is part of the ventricular system and is filled with cerebral-spinal fluid and runs the length of the spinal cord. CHEBI:35800 nitroso compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35800 CHEBI:11851 3-methyl-2-oxobutanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_11851 CHEBI:60816 immunogen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60816 CHEBI:60815 lysobisphosphatidic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60815 UBERON:0002298 brainstem biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002298 lamina pallidi incompleta|brain stem|lamina medullaris incompleta pallidi|truncus encephali|lamella pallidi incompleta|accessory medullary lamina of pallidum|lamina medullaris accessoria|truncus encephalicus Stalk-like part of the brain that includes amongst its parts the medulla oblongata of the hindbrain and the tegmentum of the midbrain[ZFA,MP,generalized]. CHEBI:60818 2,2'-lysobisphosphatidic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60818 CHEBI:60817 1,1'-lysobisphosphatidic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60817 UBERON:0002299 alveolus of lung biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002299 alveolus pulmonis|lung alveolus|pulmonary alveolus|alveoli|respiratory alveolus|alveolus|alveolus pulmonis|respiratory alveoli Spherical outcropping of the respiratory bronchioles and primary site of gas exchange with the blood. Alveoli are particular to mammalian lungs. Different structures are involved in gas exchange in other vertebrates[WP]. CHEBI:60819 diphenyl phthalate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60819 CHEBI:11807 5-hydroxy-6-methylpyridine-3,4-dicarboxylate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_11807 CHEBI:11805 3-hydroxyisobutyrate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_11805 CHEBI:60821 streptothricin F biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60821 CHEBI:60820 1-C-(indol-3-yl)glycerol 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60820 CHEBI:60823 streptothricin F acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60823 CHEBI:60822 streptothricin F(3+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60822 CHEBI:60826 streptothricin acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60826 CHEBI:60829 streptothricin D(5+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60829 CHEBI:60828 streptothricin D biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60828 NCBITaxon:46877 Drosophilini organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_46877 CHEBI:60830 streptothricin D acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60830 CHEBI:60832 tubulin modulator biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60832 CHEBI:60831 epothilone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60831 CHEBI:60833 naptalam biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60833 CHEBI:60836 phytochelatin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60836 CHEBI:60835 leucoanthocyanidin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60835 CHEBI:60838 streptothricin F acid (pH 7.3) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60838 CHEBI:60837 2',3'-cyclic GMP(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60837 CHEBI:60839 streptothricin D acid (pH 7.3) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60839 CHEBI:84805 UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84805 CHEBI:60841 2,3-dihydro-3-hydroxyanthranilic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60841 CHEBI:60843 (2R,3R)-2,3-dihydro-3-hydroxyanthranilic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60843 CHEBI:60844 (2S,3S)-2,3-dihydro-3-hydroxyanthranilic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60844 CHEBI:60847 2,3-dihydro-3-hydroxyanthranilic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60847 CHEBI:60849 (2S,3S)-2,3-dihydro-3-hydroxyanthranilic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60849 CHEBI:60848 (2R,3R)-2,3-dihydro-3-hydroxyanthranilic acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60848 CHEBI:84818 1-octadecanoyl-2-octadecenoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84818 CHEBI:84815 1,2-di-octadecadienoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84815 CHEBI:11814 3-hydroxy-3-methylglutaryl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_11814 CHEBI:84813 4-oxo-L-proline zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84813 CHEBI:11812 3-hydroxy-3-methyl-2-oxobutanoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_11812 CHEBI:60854 6-amino-5-oxocyclohex-2-ene-1-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60854 CHEBI:60858 (1S,6R)-6-amino-5-oxocyclohex-2-ene-1-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60858 CHEBI:60857 (1R,6S)-6-amino-5-oxocyclohex-2-ene-1-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60857 GO:1900639 positive regulation of asperfuranone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900639 up-regulation of asperfuranone synthesis|up-regulation of asperfuranone biosynthesis|up-regulation of asperfuranone biosynthetic process|activation of asperfuranone biosynthetic process|up-regulation of asperfuranone formation|upregulation of asperfuranone anabolism|activation of asperfuranone biosynthesis|upregulation of asperfuranone synthesis|positive regulation of asperfuranone biosynthesis|upregulation of asperfuranone formation|up regulation of asperfuranone biosynthesis|up regulation of asperfuranone biosynthetic process|up regulation of asperfuranone anabolism|positive regulation of asperfuranone anabolism|up regulation of asperfuranone synthesis|positive regulation of asperfuranone synthesis|activation of asperfuranone anabolism|up regulation of asperfuranone formation|upregulation of asperfuranone biosynthesis|upregulation of asperfuranone biosynthetic process|positive regulation of asperfuranone formation|activation of asperfuranone synthesis|up-regulation of asperfuranone anabolism|activation of asperfuranone formation Any process that activates or increases the frequency, rate or extent of asperfuranone biosynthetic process. GO:0046561 obsolete penicillopepsin activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046561 Penicillium janthinellum acid proteinase activity|Penicillium janthinellum aspartic protease activity|Penicillium aspartic proteinase activity|Penicillium cyclopium acid proteinase activity|Penicillium roqueforti acid proteinase activity|Penicillium caseicolum aspartic proteinase activity|peptidase A activity|Penicillium expansum aspartic proteinase activity|Penicillium citrinum aspartic proteinase activity|Penicillium citrinum acid proteinase activity|Penicillium expansum acid proteinase activity|acid protease A|penicillopepsin activity|Penicillium duponti aspartic proteinase activity|Penicillium janthinellum aspartic proteinase activity OBSOLETE. Catalysis of the hydrolysis of proteins with broad specificity similar to that of pepsin A, preferring hydrophobic residues at P1 and P1', but also cleaving Gly20-Glu in the B chain of insulin. Clots milk, and activates trypsinogen. UBERON:0016880 future nervous system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016880 presumptive nervous system Primordium that develops into the nervous system GO:1900638 negative regulation of asperfuranone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900638 inhibition of asperfuranone anabolism|inhibition of asperfuranone synthesis|negative regulation of asperfuranone biosynthesis|down-regulation of asperfuranone biosynthesis|down-regulation of asperfuranone biosynthetic process|inhibition of asperfuranone formation|down regulation of asperfuranone anabolism|down regulation of asperfuranone synthesis|downregulation of asperfuranone anabolism|down regulation of asperfuranone formation|downregulation of asperfuranone biosynthesis|downregulation of asperfuranone biosynthetic process|downregulation of asperfuranone synthesis|downregulation of asperfuranone formation|down regulation of asperfuranone biosynthesis|down regulation of asperfuranone biosynthetic process|down-regulation of asperfuranone anabolism|negative regulation of asperfuranone anabolism|inhibition of asperfuranone biosynthetic process|down-regulation of asperfuranone synthesis|negative regulation of asperfuranone synthesis|inhibition of asperfuranone biosynthesis|down-regulation of asperfuranone formation|negative regulation of asperfuranone formation Any process that stops, prevents or reduces the frequency, rate or extent of asperfuranone biosynthetic process. GO:0046560 obsolete scytalidopepsin B activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046560 Scytalidium lignicolum aspartic proteinase B|Ganoderma lucidum carboxyl proteinase activity|Scytalidium aspartic proteinase B activity|SLB|Ganoderma lucidum aspartic proteinase activity|scytalidopepsin B activity OBSOLETE. Catalysis of the hydrolysis of proteins with broad specificity, cleaving Phe24-Phe, but not Leu15-Tyr and Phe25-Tyr in the B chain of insulin. GO:1900635 heptadecane metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900635 heptadecane metabolism The chemical reactions and pathways involving heptadecane. GO:1900634 pentadecane biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900634 pentadecane formation|pentadecane anabolism|pentadecane synthesis|pentadecane biosynthesis The chemical reactions and pathways resulting in the formation of pentadecane. GO:1900637 regulation of asperfuranone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900637 regulation of asperfuranone anabolism|regulation of asperfuranone synthesis|regulation of asperfuranone formation|regulation of asperfuranone biosynthesis Any process that modulates the frequency, rate or extent of asperfuranone biosynthetic process. GO:1900636 heptadecane biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900636 heptadecane anabolism|heptadecane synthesis|heptadecane formation|heptadecane biosynthesis The chemical reactions and pathways resulting in the formation of heptadecane. GO:0046569 glyoxal oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046569 GLOX Catalysis of the reaction: glyoxal + O2 + H2O = glyoxalate + H2O2. GO:1900631 tridecane metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900631 tridecane metabolism The chemical reactions and pathways involving tridecane. UBERON:0016888 transitional anatomical structure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016888 An embryonic anatomical entity that will turn into one or more other anatomical entities, perhaps with other anatomical entities, later in development. GO:1900630 methanophenazine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900630 methanophenazine anabolism|methanophenazine synthesis|methanophenazine formation|methanophenazine biosynthesis The chemical reactions and pathways resulting in the formation of methanophenazine. GO:0046568 3-methylbutanol:NAD(P) oxidoreductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046568 MetaCyc:1.1.1.265-RXN|EC:1.1.1.265 isoamyl alcohol oxidase activity|3-methylbutanal reductase [NAD(P)] activity|3-methylbutyraldehyde reductase activity Catalysis of the reaction: 3-methylbutanol + NAD(P)+ = 3-methylbutanal + NAD(P)H + H+. 3-methylbutanal is also known as isovaleraldehyde. UBERON:0016887 entire extraembryonic component biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016887 extra-embryonic component|extraembryonic component The part of the conceptus that may be lost before birth or will be discarded at birth, or when the embryo becomes an independent organism. GO:0046567 aphidicolan-16 beta-ol synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046567 EC:4.2.3.42|KEGG_REACTION:R06313|RHEA:26213|MetaCyc:RXN-10631 9-alpha-copalyl-diphosphate diphosphate-lyase (aphidicolan-16-beta-ol-forming) Catalysis of the reaction: 9-alpha-copalyl diphosphate + H2O = aphidicolan-16-beta-ol + diphosphate. GO:1900633 pentadecane metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900633 pentadecane metabolism The chemical reactions and pathways involving pentadecane. GO:0046566 DOPA dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046566 MetaCyc:RXN-8460 dihydroxyphenylalanine dioxygenase activity Catalysis of the 4,5-ring opening reaction: 3,4-dihydroxyphenylalanine + O2 = 4,5-seco-DOPA. 4,5-seco-DOPA spontaneously recyclizes to form betalamic acid. GO:1900632 tridecane biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900632 tridecane biosynthesis|tridecane anabolism|tridecane synthesis|tridecane formation The chemical reactions and pathways resulting in the formation of tridecane. UBERON:0016884 shoulder joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016884 joint of shoulder region The joint that is formed by the union of the humerus, the scapula (or shoulder blade), and the clavicle (or collarbone). Commonly thought of as a single joint, the shoulder is actually made up of two separate joints - the glenohumeral and acromioclavicular joints GO:0046565 3-dehydroshikimate dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046565 EC:4.2.1.118|MetaCyc:DHSHIKIMATE-DEHYDRO-RXN|RHEA:24848 Catalysis of the reaction: 3-dehydroshikimate = 3,4-dihydroxybenzoate + H2O. 3,4-dihydroxybenzoate is also known as protocatechuate. UBERON:2000001 Kupffer's vesicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_2000001 Small but distinctive epithelial sac containing fluid, located midventrally posterior to the yolk cell or its extension, and transiently present during most of the segmentation period. Kimmel et al, 1995. Kupffer's vesicle has been compared to the mouse embryonic node. Drummond et al, 2005. GO:0046564 oxalate decarboxylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046564 EC:4.1.1.2|MetaCyc:OXALATE-DECARBOXYLASE-RXN|RHEA:16509|KEGG_REACTION:R00522 oxalate carboxy-lyase activity|oxalate carboxy-lyase (formate-forming) Catalysis of the reaction: H(+) + oxalate = CO(2) + formate. UBERON:0016886 muscle tissue of terminal part of digestive tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016886 rectum muscle|rectum muscle structure Any muscle tissue of the distalmost portion of the digestive tract. GO:0046563 methanol oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046563 MetaCyc:METHANOL-OXIDASE-RXN|EC:1.1.3.- Catalysis of the reaction: O2 + methanol = H2O2 + formaldehyde. GO:0046562 glucose oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046562 EC:1.1.3.4|MetaCyc:GLUCOSE-OXIDASE-RXN|RHEA:11428|KEGG_REACTION:R01522 D-glucose-1-oxidase activity|corylophyline|beta-D-glucose:oxygen 1-oxido-reductase activity|D-glucose oxidase activity|microcid|glucose oxyhydrase activity|deoxin-1|GOD activity|beta-D-glucose:oxygen 1-oxidoreductase activity|penatin|glucose aerodehydrogenase activity|beta-D-glucose oxidase activity|beta-D-glucose:quinone oxidoreductase activity Catalysis of the reaction: beta-D-glucose + O2 = D-glucono-1,5-lactone + H2O2. UBERON:0016885 epithelium of terminal part of digestive tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016885 rectum epithelium Epithelium lining the distalmost portion of the digestive tract. UBERON:0002241 chondrocranium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002241 neurocranium|calvarium Endoskeletal elements that encase the brain, nose, inner ear[cjm]. that part of the neurocranium formed by endochondral ossification and comprising the bones of the base of the skull[TFD]. UBERON:0002240 spinal cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002240 SpC|spinal medulla|spinal cord structure|medulla spinalis|fissura cerebrocerebellaris|cerebrocerebellar fissure|fissura cerebro-cerebellaris|cerebro-cerebellar fissure Part of the central nervous system located in the vertebral canal continuous with and caudal to the brain; demarcated from brain by plane of foramen magnum. It is composed of an inner core of gray matter in which nerve cells predominate, and an outer layer of white matter in which myelinated nerve fibers predominate, and surrounds the central canal. (CUMBO) GO:0071529 cementum mineralization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071529 cementum formation The process in which calcium salts, mainly carbonated hydroxyapatite, are deposited into the initial acellular cementum. GO:0071528 tRNA re-export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071528 tRNA reexport from nucleus The directed movement from the nucleus to the cytoplasm of a tRNA that was previously exported to the cytoplasm and then imported back into the nucleus. The processes of primary tRNA export and secondary export (re-export) can be distinguished because in organisms in which tRNA splicing occurs in the cytoplasm, the export of a mature tRNA must occur by re-export. CHEBI:35897 but-3-enoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35897 GO:0071527 semaphorin-plexin signaling pathway involved in outflow tract morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071527 semaphorin-plexin signalling pathway involved in outflow tract morphogenesis A series of molecular signals generated as a consequence of a semaphorin receptor (composed of a plexin and a neurophilin) binding to a semaphorin ligand that contributes to outflow tract morphogenesis. GO:0071526 semaphorin-plexin signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071526 semaphorin-plexin signalling pathway A series of molecular signals generated as a consequence of a semaphorin receptor (composed of a plexin and a neurophilin) binding to a semaphorin ligand. CHEBI:35899 crotonate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35899 GO:0071525 pyrrolysine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071525 pyrrolysine metabolism|monomethylamine methyltransferase cofactor lysine adduct metabolic process The chemical reactions and pathways involving pyrrolysine, N6-{[(2R,3R)-3-methyl-3,4-dihydro-2H-pyrrol-2-yl]carbonyl}-L-lysine. CHEBI:59869 L-alpha-amino acid zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59869 GO:0071524 pyrrolysine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071524 pyrrolysine anabolism|monomethylamine methyltransferase cofactor lysine adduct biosynthetic process|pyrrolysine synthesis|pyrrolysine formation|pyrrolysine biosynthesis The chemical reactions and pathways resulting in the formation of pyrrolysine, N6-{[(2R,3R)-3-methyl-3,4-dihydro-2H-pyrrol-2-yl]carbonyl}-L-lysine. GO:0071523 obsolete TIR domain-mediated complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071523 OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a TIR domain interaction. GO:0071522 ureidoglycine aminohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071522 EC:3.5.3.26|MetaCyc:URUR-RXN|RHEA:25241 Catalysis of the reaction: ureidoglycine + H2O = S-ureidoglycolate + NH3. GO:0071521 Cdc42 GTPase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071521 Ras1-Scd1-Scd2-Cdc42-Shk1 complex A protein complex formed by the association of the small GTPase Cdc42 with additional proteins. In Schizosaccharomyces the complex contains the Cdc42, Ras1, Scd1, Scd2, andShk1 proteins, and functions in the Ras1-Scd GTPase signalling pathway. CHEBI:59864 depigmentation drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59864 GO:0071520 actomyosin contractile ring assembly actin filament bundle convergence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071520 actin filament bundle convergence involved in actomyosin contractile ring formation|actin filament bundle convergence involved in cytokinetic actomyosin contractile ring assembly A process of actin filament bundle distribution that occurs in the context of assembling an actomyosin contractile ring during cytokinesis, and that results in the compaction of actin filaments into a tight ring. CHEBI:59863 D-fructofuranuronate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59863 UBERON:0002244 premaxilla biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002244 premaxillae|os incisivum|premaxilla bone|premaxillary|premaxillary bone|incisive bone One of the bones of the upper jaw situated between and in front of the maxillae[VHOG]. GO:0046572 versicolorin B synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046572 RHEA:33859|MetaCyc:RXN-9494|EC:4.2.1.143 Catalysis of the reaction: versiconal = versicolorin B + H2O. GO:1900649 regulation of dehydroaustinol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900649 regulation of dehydroaustinol biosynthesis|regulation of dehydroaustinol anabolism|regulation of dehydroaustinol synthesis|regulation of dehydroaustinol formation Any process that modulates the frequency, rate or extent of dehydroaustinol biosynthetic process. GO:0046571 aspartate-2-keto-4-methylthiobutyrate transaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046571 Catalysis of the reaction: 2-keto-4-methylthiobutyrate + aspartate = methionine + oxaloacetate. GO:0046570 methylthioribulose 1-phosphate dehydratase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046570 Reactome:R-HSA-1237140|RHEA:15549|MetaCyc:R145-RXN|EC:4.2.1.109|KEGG_REACTION:R07392 5-methylthioribulose-1-phosphate 4-dehydratase activity|S-methyl-5-thio-D-ribulose-1-phosphate hydro-lyase [5-(methylthio)-2,3-dioxopentyl-phosphate-forming]|S-methyl-5-thio-D-ribulose-1-phosphate hydro-lyase activity|methylthioribulose-1-phosphate dehydratase activity|1-PMT-ribulose dehydratase activity|S-methyl-5-thio-D-ribulose-1-phosphate hydro-lyase[5-(methylthio)-2,3-dioxopentyl-phosphate-forming] Catalysis of the reaction: S-methyl-5-thio-D-ribulose 1-phosphate = 5-(methylthio)-2,3-dioxopentyl phosphate + H(2)O. GO:1900646 regulation of chanoclavine-I aldehyde biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900646 regulation of chanoclavine-I aldehyde synthesis|regulation of chanoclavine-I aldehyde formation|regulation of chanoclavine-I aldehyde anabolism|regulation of chanoclavine-I aldehyde biosynthesis Any process that modulates the frequency, rate or extent of chanoclavine-I aldehyde biosynthetic process. GO:1900645 positive regulation of chanoclavine-I biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900645 up-regulation of chanoclavine-I anabolism|upregulation of chanoclavine-I biosynthetic process|upregulation of chanoclavine-I biosynthesis|up-regulation of chanoclavine-I synthesis|activation of chanoclavine-I anabolism|up-regulation of chanoclavine-I formation|activation of chanoclavine-I synthesis|up regulation of chanoclavine-I biosynthetic process|positive regulation of chanoclavine-I anabolism|up regulation of chanoclavine-I biosynthesis|up regulation of chanoclavine-I anabolism|activation of chanoclavine-I formation|activation of chanoclavine-I biosynthetic process|positive regulation of chanoclavine-I biosynthesis|positive regulation of chanoclavine-I synthesis|up regulation of chanoclavine-I synthesis|positive regulation of chanoclavine-I formation|activation of chanoclavine-I biosynthesis|up regulation of chanoclavine-I formation|upregulation of chanoclavine-I anabolism|up-regulation of chanoclavine-I biosynthesis|up-regulation of chanoclavine-I biosynthetic process|upregulation of chanoclavine-I synthesis|upregulation of chanoclavine-I formation Any process that activates or increases the frequency, rate or extent of chanoclavine-I biosynthetic process. UBERON:0002228 rib biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002228 ribs|dorsal rib|pleural rib An intersegmental rod-shaped bone that forms in the peritoneal membrane and attach to the vertebral parapophyses. GO:1900648 positive regulation of chanoclavine-I aldehyde biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900648 upregulation of chanoclavine-I aldehyde biosynthetic process|up regulation of chanoclavine-I aldehyde anabolism|upregulation of chanoclavine-I aldehyde biosynthesis|positive regulation of chanoclavine-I aldehyde anabolism|up regulation of chanoclavine-I aldehyde synthesis|positive regulation of chanoclavine-I aldehyde synthesis|up regulation of chanoclavine-I aldehyde formation|activation of chanoclavine-I aldehyde anabolism|up-regulation of chanoclavine-I aldehyde biosynthesis|up-regulation of chanoclavine-I aldehyde biosynthetic process|positive regulation of chanoclavine-I aldehyde formation|activation of chanoclavine-I aldehyde biosynthetic process|activation of chanoclavine-I aldehyde synthesis|up-regulation of chanoclavine-I aldehyde anabolism|activation of chanoclavine-I aldehyde formation|activation of chanoclavine-I aldehyde biosynthesis|up-regulation of chanoclavine-I aldehyde synthesis|positive regulation of chanoclavine-I aldehyde biosynthesis|up-regulation of chanoclavine-I aldehyde formation|up regulation of chanoclavine-I aldehyde biosynthesis|upregulation of chanoclavine-I aldehyde anabolism|up regulation of chanoclavine-I aldehyde biosynthetic process|upregulation of chanoclavine-I aldehyde synthesis|upregulation of chanoclavine-I aldehyde formation Any process that activates or increases the frequency, rate or extent of chanoclavine-I aldehyde biosynthetic process. GO:1900647 negative regulation of chanoclavine-I aldehyde biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900647 inhibition of chanoclavine-I aldehyde biosynthetic process|down regulation of chanoclavine-I aldehyde formation|downregulation of chanoclavine-I aldehyde synthesis|inhibition of chanoclavine-I aldehyde biosynthesis|downregulation of chanoclavine-I aldehyde formation|down-regulation of chanoclavine-I aldehyde anabolism|negative regulation of chanoclavine-I aldehyde anabolism|down-regulation of chanoclavine-I aldehyde synthesis|negative regulation of chanoclavine-I aldehyde synthesis|down-regulation of chanoclavine-I aldehyde formation|negative regulation of chanoclavine-I aldehyde formation|down-regulation of chanoclavine-I aldehyde biosynthesis|negative regulation of chanoclavine-I aldehyde biosynthesis|down-regulation of chanoclavine-I aldehyde biosynthetic process|inhibition of chanoclavine-I aldehyde anabolism|inhibition of chanoclavine-I aldehyde synthesis|inhibition of chanoclavine-I aldehyde formation|downregulation of chanoclavine-I aldehyde biosynthesis|down regulation of chanoclavine-I aldehyde anabolism|downregulation of chanoclavine-I aldehyde biosynthetic process|downregulation of chanoclavine-I aldehyde anabolism|down regulation of chanoclavine-I aldehyde biosynthesis|down regulation of chanoclavine-I aldehyde synthesis|down regulation of chanoclavine-I aldehyde biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of chanoclavine-I aldehyde biosynthetic process. GO:1900642 positive regulation of austinol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900642 upregulation of austinol anabolism|up regulation of austinol biosynthesis|up regulation of austinol biosynthetic process|activation of austinol biosynthetic process|positive regulation of austinol biosynthesis|upregulation of austinol synthesis|activation of austinol biosynthesis|upregulation of austinol formation|up-regulation of austinol anabolism|up-regulation of austinol synthesis|up-regulation of austinol biosynthesis|up-regulation of austinol biosynthetic process|activation of austinol anabolism|up-regulation of austinol formation|activation of austinol synthesis|positive regulation of austinol anabolism|activation of austinol formation|upregulation of austinol biosynthetic process|up regulation of austinol anabolism|upregulation of austinol biosynthesis|positive regulation of austinol synthesis|up regulation of austinol synthesis|positive regulation of austinol formation|up regulation of austinol formation Any process that activates or increases the frequency, rate or extent of austinol biosynthetic process. GO:1900641 negative regulation of austinol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900641 down regulation of austinol synthesis|inhibition of austinol anabolism|down regulation of austinol formation|negative regulation of austinol biosynthesis|down-regulation of austinol biosynthesis|down-regulation of austinol biosynthetic process|inhibition of austinol synthesis|inhibition of austinol formation|inhibition of austinol biosynthetic process|down-regulation of austinol anabolism|negative regulation of austinol anabolism|inhibition of austinol biosynthesis|down-regulation of austinol synthesis|negative regulation of austinol synthesis|down-regulation of austinol formation|negative regulation of austinol formation|down regulation of austinol biosynthetic process|down regulation of austinol biosynthesis|downregulation of austinol anabolism|downregulation of austinol synthesis|downregulation of austinol biosynthesis|down regulation of austinol anabolism|downregulation of austinol biosynthetic process|downregulation of austinol formation Any process that stops, prevents or reduces the frequency, rate or extent of austinol biosynthetic process. GO:0046579 positive regulation of Ras protein signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046579 up-regulation of Ras protein signal transduction|upregulation of Ras protein signal transduction|up regulation of Ras protein signal transduction|activation of Ras protein signal transduction|stimulation of Ras protein signal transduction Any process that activates or increases the frequency, rate or extent of Ras protein signal transduction. GO:1900644 negative regulation of chanoclavine-I biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900644 inhibition of chanoclavine-I formation|down regulation of chanoclavine-I biosynthesis|down regulation of chanoclavine-I biosynthetic process|down-regulation of chanoclavine-I anabolism|negative regulation of chanoclavine-I anabolism|downregulation of chanoclavine-I biosynthesis|downregulation of chanoclavine-I biosynthetic process|down-regulation of chanoclavine-I synthesis|negative regulation of chanoclavine-I synthesis|down-regulation of chanoclavine-I formation|negative regulation of chanoclavine-I formation|downregulation of chanoclavine-I anabolism|negative regulation of chanoclavine-I biosynthesis|down-regulation of chanoclavine-I biosynthesis|down-regulation of chanoclavine-I biosynthetic process|down regulation of chanoclavine-I anabolism|downregulation of chanoclavine-I synthesis|downregulation of chanoclavine-I formation|inhibition of chanoclavine-I biosynthetic process|down regulation of chanoclavine-I synthesis|inhibition of chanoclavine-I anabolism|down regulation of chanoclavine-I formation|inhibition of chanoclavine-I biosynthesis|inhibition of chanoclavine-I synthesis Any process that stops, prevents or reduces the frequency, rate or extent of chanoclavine-I biosynthetic process. UBERON:0016879 future central nervous system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016879 future CNS|presumptive central nervous system Primordium that develops into the central nervous system GO:0046578 regulation of Ras protein signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046578 Any process that modulates the frequency, rate or extent of Ras protein signal transduction. GO:0046577 long-chain-alcohol oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046577 RHEA:22756|EC:1.1.3.20|MetaCyc:LONG-CHAIN-ALCOHOL-OXIDASE-RXN fatty alcohol oxidase activity|long-chain fatty acid oxidase activity|fatty alcohol:oxygen oxidoreductase activity|long-chain fatty alcohol oxidase activity|long-chain-alcohol:oxygen oxidoreductase activity Catalysis of the reaction: 2 long-chain alcohol + O2 = 2 long-chain aldehyde + 2 H2O. GO:1900643 regulation of chanoclavine-I biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900643 regulation of chanoclavine-I biosynthesis|regulation of chanoclavine-I anabolism|regulation of chanoclavine-I synthesis|regulation of chanoclavine-I formation Any process that modulates the frequency, rate or extent of chanoclavine-I biosynthetic process. GO:0046576 rhamnogalacturonan alpha-L-rhamnopyranosyl-(1->4)-alpha-D-galactopyranosyluronide lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046576 rhamnogalacturonase B activity Catalysis of the cleavage of rhamnogalacturonan, generating oligosaccharides of the form alpha-D-us-galacturonic acid-(1,2)-alpha-L-rhamnose-(1,4)-alpha-D-galacturonate-(1,2)-L-rhamnose-(1,2)-alpha-L-rhamnose-p-(1,4)-alpha-D-galacturonic acid, terminating at the non-reducing end with a hex-4-enopyranosyluronic acid residue. CHEBI:21260 cysteic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21260 GO:0046575 rhamnogalacturonan acetylesterase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046575 Catalysis of the removal of acetylesters (as acetate) from galacturonic acid residues in the backbone of rhamnogalacturonan. PR:000021260 renin proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000021260 REN/ClvPrd A renin that has been processed by proteolytic cleavage. CHEBI:45212 diphosphate(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_45212 GO:1900640 regulation of austinol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900640 regulation of austinol formation|regulation of austinol anabolism|regulation of austinol biosynthesis|regulation of austinol synthesis Any process that modulates the frequency, rate or extent of austinol biosynthetic process. GO:0046574 glycuronidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046574 glucuronyl hydrolase activity Catalysis of the hydrolysis of glucuronosides, yielding free glucuronic acid. GO:0046573 lactonohydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046573 Catalysis of the hydrolysis of lactone rings (intramolecular cyclic esters) to produce a hydroxyl group and a carboxyl group. GO:0071519 actomyosin contractile ring actin filament bundle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071519 actin filament bundle assembly involved in cytokinetic actomyosin contractile ring assembly|actin filament bundle assembly involved in actomyosin contractile ring formation A process of actin filament bundle formation that occurs in the context of assembling an actomyosin contractile ring during cytokinesis. GO:0071518 autoinducer-2 kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071518 MetaCyc:RXN0-5461|RHEA:15377 4,5-dihydroxy-pentane-2,3-dione kinase activity Catalysis of the reaction: 4,5-dihydroxy-pentane-2,3-dione + ATP = 5-phospho-4-hydroxy-pentane-2,3-dione (P-DPD) + ADP. GO:0071517 maintenance of imprinting at mating-type locus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071517 mating type determination, maintenance of imprinting Any process involved in preserving the structure of a stable single-strand DNA lesion that triggers programmed gene conversion at the mating-type locus, thereby restricting mating-type interconversion to one of the two sister chromatids during DNA replication. GO:0071516 establishment of imprinting at mating-type locus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071516 mating type determination, establishment of imprinting The initial formation of a stable single-strand DNA lesion that triggers programmed gene conversion at the mating-type locus, thereby restricting mating-type interconversion to one of the two sister chromatids during DNA replication. GO:0071515 genetic imprinting at mating-type locus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071515 mating type determination, imprinting A genetic imprinting process in which a stable single-strand DNA lesion triggers programmed gene conversion at the mating-type locus, thereby restricting mating-type interconversion to one of the two sister chromatids during DNA replication. GO:0071514 genetic imprinting biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071514 DNA imprinting Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules by a mechanism that is mediated by DNA, is mitotically or meiotically heritable, or is stably self-propagated in the cytoplasm of a resting cell, and does not entail a change in DNA sequence. GO:0071513 phosphopantothenoylcysteine decarboxylase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071513 A protein complex that catalyzes decarboxylation of 4'-phosphopantothenoylcysteine to yield 4'-phosphopantetheine; this is the third step in the biosynthesis of Coenzyme A. The complex is homotrimeric in many eukaryotes, but is a heterotrimer in Saccharomyces. GO:0071512 obsolete MAPK import into nucleus involved in conjugation with cellular fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071512 conjugation with cellular fusion, nuclear translocation of MAPK|MAPK import into nucleus involved in mating response|conjugation with cellular fusion, MAPK import into nucleus|nuclear translocation of MAPK involved in mating response|nuclear translocation of MAPK involved in conjugation with cellular fusion OBSOLETE. The directed movement of a MAP kinase to the nucleus that occurs in the context of conjugation with cellular fusion. UBERON:0002237 true rib biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002237 costae verae|costa vera A rib that is ventrally connected to the sternum. GO:0071511 inactivation of MAPK activity involved in conjugation with cellular fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071511 conjugation with cellular fusion, termination of MAPK activity|conjugation with cellular fusion, inactivation of MAPK activity|termination of MAPK activity during conjugation with cellular fusion|inactivation of MAPK activity involved in mating response Any process that terminates the activity of the active enzyme MAP kinase in the context of conjugation with cellular fusion. GO:0071510 activation of MAPKKK activity involved in conjugation with cellular fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071510 activation of MAP kinase kinase kinase activity during conjugation with cellular fusion|conjugation with cellular fusion, activation of MAPKKK activity|activation of MAPKKK activity involved in mating response|conjugation with cellular fusion, activation of MAP kinase kinase kinase activity Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase in the context of conjugation with cellular fusion. UBERON:0002234 proximal phalanx of manus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002234 proximal phalanx of manual digit|proximal phalanx of hand|phalanx proximalis manus|proximal phalanx of fore digit|proximal manual phalanx|proximal phalanx of finger|hand proximal phalanx A proximal phalanx that is part of a finger [Automatically generated definition]. GO:0095500 acetylcholine receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0095500 acetylcholine receptor signalling pathway The series of molecular signals generated as a consequence of an acetylcholine receptor binding to one of its physiological ligands. GO:0046583 cation efflux transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046583 cation efflux permease activity Enables the transfer of a cation or cations from the inside of the cell to the outside of the cell across a membrane. GO:0046582 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046582 GO:0046581 intercellular canaliculus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0046581 An extremely narrow tubular channel located between adjacent cells. An instance of this is the secretory canaliculi occurring between adjacent parietal cells in the gastric mucosa of vertebrates. GO:0046580 negative regulation of Ras protein signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046580 downregulation of Ras protein signal transduction|down-regulation of Ras protein signal transduction|inhibition of Ras protein signal transduction|down regulation of Ras protein signal transduction Any process that stops, prevents, or reduces the frequency, rate or extent of Ras protein signal transduction. GO:1900657 positive regulation of diorcinol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900657 up-regulation of diorcinol synthesis|up-regulation of diorcinol formation|positive regulation of diorcinol biosynthesis|up regulation of diorcinol biosynthetic process|up regulation of diorcinol biosynthesis|upregulation of diorcinol anabolism|upregulation of diorcinol synthesis|upregulation of diorcinol formation|up regulation of diorcinol anabolism|upregulation of diorcinol biosynthetic process|upregulation of diorcinol biosynthesis|positive regulation of diorcinol anabolism|up regulation of diorcinol synthesis|positive regulation of diorcinol synthesis|up regulation of diorcinol formation|activation of diorcinol anabolism|up-regulation of diorcinol biosynthetic process|up-regulation of diorcinol biosynthesis|positive regulation of diorcinol formation|activation of diorcinol biosynthetic process|activation of diorcinol synthesis|up-regulation of diorcinol anabolism|activation of diorcinol formation|activation of diorcinol biosynthesis Any process that activates or increases the frequency, rate or extent of diorcinol biosynthetic process. GO:1900656 negative regulation of diorcinol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900656 inhibition of diorcinol anabolism|inhibition of diorcinol synthesis|downregulation of diorcinol biosynthetic process|downregulation of diorcinol biosynthesis|inhibition of diorcinol formation|down regulation of diorcinol anabolism|down regulation of diorcinol biosynthetic process|downregulation of diorcinol anabolism|down regulation of diorcinol biosynthesis|down regulation of diorcinol synthesis|inhibition of diorcinol biosynthetic process|down regulation of diorcinol formation|downregulation of diorcinol synthesis|inhibition of diorcinol biosynthesis|downregulation of diorcinol formation|down-regulation of diorcinol anabolism|negative regulation of diorcinol anabolism|down-regulation of diorcinol synthesis|negative regulation of diorcinol synthesis|down-regulation of diorcinol formation|negative regulation of diorcinol formation|negative regulation of diorcinol biosynthesis|down-regulation of diorcinol biosynthesis|down-regulation of diorcinol biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of diorcinol biosynthetic process. UBERON:0002217 synovial joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002217 diarthrosis joint|diarthroses|diarthrosis|articulatio synoviale|diarthrodial joints Joint in which the articulating bones or cartilages are connected by an articular capsule which encloses a synovial membrane and a synovial cavity. Examples: Temporomandibular joint, knee joint.[FMA] GO:1900659 negative regulation of emericellamide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900659 downregulation of emericellamide formation|down regulation of emericellamide synthesis|down regulation of emericellamide formation|inhibition of emericellamide anabolism|inhibition of emericellamide synthesis|down-regulation of emericellamide biosynthetic process|negative regulation of emericellamide biosynthesis|down-regulation of emericellamide biosynthesis|inhibition of emericellamide formation|inhibition of emericellamide biosynthetic process|negative regulation of emericellamide anabolism|down-regulation of emericellamide anabolism|negative regulation of emericellamide synthesis|inhibition of emericellamide biosynthesis|down-regulation of emericellamide synthesis|negative regulation of emericellamide formation|down-regulation of emericellamide formation|downregulation of emericellamide anabolism|down regulation of emericellamide biosynthesis|down regulation of emericellamide biosynthetic process|down regulation of emericellamide anabolism|downregulation of emericellamide synthesis|downregulation of emericellamide biosynthesis|downregulation of emericellamide biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of emericellamide biosynthetic process. GO:1900658 regulation of emericellamide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900658 regulation of emericellamide formation|regulation of emericellamide anabolism|regulation of emericellamide biosynthesis|regulation of emericellamide synthesis Any process that modulates the frequency, rate or extent of emericellamide biosynthetic process. CHEBI:59848 thia fatty acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59848 GO:1900653 negative regulation of demethylkotanin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900653 down regulation of demethylkotanin anabolism|inhibition of demethylkotanin formation|down-regulation of demethylkotanin biosynthetic process|down-regulation of demethylkotanin biosynthesis|negative regulation of demethylkotanin biosynthesis|downregulation of demethylkotanin anabolism|down regulation of demethylkotanin synthesis|down regulation of demethylkotanin formation|downregulation of demethylkotanin synthesis|downregulation of demethylkotanin biosynthesis|downregulation of demethylkotanin biosynthetic process|downregulation of demethylkotanin formation|down-regulation of demethylkotanin anabolism|negative regulation of demethylkotanin anabolism|down regulation of demethylkotanin biosynthetic process|down regulation of demethylkotanin biosynthesis|inhibition of demethylkotanin biosynthetic process|down-regulation of demethylkotanin synthesis|negative regulation of demethylkotanin synthesis|down-regulation of demethylkotanin formation|negative regulation of demethylkotanin formation|inhibition of demethylkotanin biosynthesis|inhibition of demethylkotanin anabolism|inhibition of demethylkotanin synthesis Any process that stops, prevents or reduces the frequency, rate or extent of demethylkotanin biosynthetic process. GO:1900652 regulation of demethylkotanin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900652 regulation of demethylkotanin anabolism|regulation of demethylkotanin synthesis|regulation of demethylkotanin formation|regulation of demethylkotanin biosynthesis Any process that modulates the frequency, rate or extent of demethylkotanin biosynthetic process. GO:0046589 ribonuclease T1 activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046589 EC:3.1.27.3|MetaCyc:3.1.27.3-RXN RNase G|ribonuclease guaninenucleotido-2'-transferase (cyclizing)|RNase T1 activity|ribonuclease F1|ribonuclease U1|RNase Sa|RNase F1|Aspergillus oryzae ribonuclease activity|ribonuclease PP1|ribonuclease C2|guanyloribonuclease activity|ribonuclease SA|guanyl-specific RNase activity|RNase T1|RNase N1 activity|ribonuclease N3|ribonuclease Ch|binase activity|RNase N2 activity|ribonuclease N1 Catalysis of the endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Gp with 2',3'-cyclic phosphate intermediates. GO:1900655 regulation of diorcinol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900655 regulation of diorcinol anabolism|regulation of diorcinol biosynthesis|regulation of diorcinol synthesis|regulation of diorcinol formation Any process that modulates the frequency, rate or extent of diorcinol biosynthetic process. GO:1900654 positive regulation of demethylkotanin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900654 upregulation of demethylkotanin anabolism|activation of demethylkotanin biosynthesis|upregulation of demethylkotanin synthesis|upregulation of demethylkotanin formation|positive regulation of demethylkotanin biosynthesis|up regulation of demethylkotanin anabolism|up regulation of demethylkotanin biosynthesis|up regulation of demethylkotanin biosynthetic process|positive regulation of demethylkotanin anabolism|up regulation of demethylkotanin synthesis|positive regulation of demethylkotanin synthesis|up regulation of demethylkotanin formation|activation of demethylkotanin anabolism|positive regulation of demethylkotanin formation|upregulation of demethylkotanin biosynthetic process|upregulation of demethylkotanin biosynthesis|activation of demethylkotanin synthesis|up-regulation of demethylkotanin anabolism|activation of demethylkotanin formation|up-regulation of demethylkotanin synthesis|activation of demethylkotanin biosynthetic process|up-regulation of demethylkotanin biosynthesis|up-regulation of demethylkotanin biosynthetic process|up-regulation of demethylkotanin formation Any process that activates or increases the frequency, rate or extent of demethylkotanin biosynthetic process. GO:0046588 negative regulation of calcium-dependent cell-cell adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046588 down-regulation of calcium-dependent cell-cell adhesion|downregulation of calcium-dependent cell-cell adhesion|down regulation of calcium-dependent cell-cell adhesion|inhibition of calcium-dependent cell-cell adhesion Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-dependent cell-cell adhesion. GO:0046587 positive regulation of calcium-dependent cell-cell adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046587 up regulation of calcium-dependent cell-cell adhesion|upregulation of calcium-dependent cell-cell adhesion|stimulation of calcium-dependent cell-cell adhesion|up-regulation of calcium-dependent cell-cell adhesion|activation of calcium-dependent cell-cell adhesion Any process that activates or increases the frequency, rate or extent of calcium-dependent cell-cell adhesion. GO:0046586 regulation of calcium-dependent cell-cell adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046586 Any process that modulates the frequency, rate or extent of the attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction. GO:1900651 positive regulation of dehydroaustinol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900651 activation of dehydroaustinol biosynthetic process|upregulation of dehydroaustinol formation|up regulation of dehydroaustinol anabolism|activation of dehydroaustinol biosynthesis|positive regulation of dehydroaustinol anabolism|up regulation of dehydroaustinol synthesis|positive regulation of dehydroaustinol biosynthesis|positive regulation of dehydroaustinol synthesis|up regulation of dehydroaustinol formation|activation of dehydroaustinol anabolism|up regulation of dehydroaustinol biosynthetic process|up regulation of dehydroaustinol biosynthesis|positive regulation of dehydroaustinol formation|activation of dehydroaustinol synthesis|up-regulation of dehydroaustinol anabolism|activation of dehydroaustinol formation|up-regulation of dehydroaustinol synthesis|upregulation of dehydroaustinol biosynthetic process|upregulation of dehydroaustinol biosynthesis|up-regulation of dehydroaustinol formation|upregulation of dehydroaustinol anabolism|upregulation of dehydroaustinol synthesis|up-regulation of dehydroaustinol biosynthetic process|up-regulation of dehydroaustinol biosynthesis Any process that activates or increases the frequency, rate or extent of dehydroaustinol biosynthetic process. GO:0046585 enniatin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046585 enniatin anabolism|enniatin biosynthesis|enniatin synthesis|enniatin formation The chemical reactions and pathways resulting in the formation of enniatins, any of various cyclodepsipeptide antibiotics from Fusarium species that function as ionophores. GO:1900650 negative regulation of dehydroaustinol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900650 downregulation of dehydroaustinol anabolism|down regulation of dehydroaustinol synthesis|down regulation of dehydroaustinol formation|downregulation of dehydroaustinol synthesis|down-regulation of dehydroaustinol biosynthesis|down-regulation of dehydroaustinol biosynthetic process|negative regulation of dehydroaustinol biosynthesis|downregulation of dehydroaustinol formation|negative regulation of dehydroaustinol anabolism|down-regulation of dehydroaustinol anabolism|negative regulation of dehydroaustinol synthesis|down-regulation of dehydroaustinol synthesis|downregulation of dehydroaustinol biosynthesis|downregulation of dehydroaustinol biosynthetic process|negative regulation of dehydroaustinol formation|down-regulation of dehydroaustinol formation|down regulation of dehydroaustinol biosynthetic process|down regulation of dehydroaustinol biosynthesis|inhibition of dehydroaustinol biosynthetic process|inhibition of dehydroaustinol anabolism|inhibition of dehydroaustinol biosynthesis|inhibition of dehydroaustinol synthesis|inhibition of dehydroaustinol formation|down regulation of dehydroaustinol anabolism Any process that stops, prevents or reduces the frequency, rate or extent of dehydroaustinol biosynthetic process. GO:0046584 enniatin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046584 enniatin metabolism The chemical reactions and pathways involving enniatins, any of various cyclodepsipeptide antibiotics from Fusarium species that function as ionophores. CHEBI:35871 oxo monocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35871 CHEBI:35873 carboxylic anhydride biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35873 CHEBI:35875 imidazopyrimidine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35875 GO:0071549 cellular response to dexamethasone stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071549 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus. GO:0071548 response to dexamethasone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071548 response to dexamethasone stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus. GO:0071547 piP-body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071547 A P granule that contains the PIWIL4-TDRD9 module, a set of proteins that act in the secondary piRNA pathway. CHEBI:21239 arogenic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21239 UBERON:0002224 thoracic cavity biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002224 cavitas thoracis|cavity of thorax|pectoral cavity|cavity of chest|thoracic lumen|chest cavity|space of thoracic compartment The part of the coelemic cavity lumen that is enclosed by the walls of the thorax. GO:0071546 pi-body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071546 intermitochondrial cement A P granule that contains the PIWIL2-TDRD1 module, a set of proteins that act in the primary piRNA pathway. The pi-body corresponds to the cementing material between mitochondria found in gonocytes. GO:0071545 inositol phosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071545 inositol phosphate degradation|inositol phosphate breakdown|inositol phosphate catabolism|myo-inositol phosphate catabolic process The chemical reactions and pathways resulting in the breakdown of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached. CHEBI:59845 3-hydroxy fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59845 GO:0071544 diphosphoinositol polyphosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071544 diphosphoinositol polyphosphate breakdown|diphosphoinositol polyphosphate catabolism|diphosphoinositol polyphosphate degradation The chemical reactions and pathways resulting in the breakdown of a diphosphoinositol polyphosphate, 1,2,3,4,5,6-cyclohexanehexol with one or more diphosphate groups and multiple monophosphate groups attached. GO:0071543 diphosphoinositol polyphosphate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071543 diphosphoinositol polyphosphate metabolism The chemical reactions and pathways involving a diphosphoinositol polyphosphate, 1,2,3,4,5,6-cyclohexanehexol with one or more diphosphate groups and multiple monophosphate groups attached. GO:0071542 dopaminergic neuron differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071542 The process in which a neuroblast acquires the specialized structural and functional features of a dopaminergic neuron, a neuron that secretes dopamine. GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071541 eIF3m-containing eukaryotic translation initiation factor 3 complex An eukaryotic translation initiation factor 3 complex that contains the PCI-domain protein eIF3m. UBERON:0002222 perichondrium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002222 cartilage connective tissue|perichondral region of cartilage|perichondral region of cartilage element Fibrous connective tissue that surrounds cartilage. GO:0071540 eukaryotic translation initiation factor 3 complex, eIF3e biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071540 eIF3e-containing eukaryotic translation initiation factor 3 complex An eukaryotic translation initiation factor 3 complex that contains the PCI-domain protein eIF3e. GO:0046594 maintenance of pole plasm mRNA location biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046594 maintenance of oocyte pole plasm mRNA localization|maintenance of pole plasm mRNA localization The process of maintaining mRNA in a specific location in the oocyte pole plasm. An example of this process is found in Drosophila melanogaster. GO:0046593 mandelonitrile lyase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046593 MetaCyc:MANDELONITRILE-LYASE-RXN|EC:4.1.2.10|RHEA:18313 D-alpha-hydroxynitrile lyase activity|mandelonitrile benzaldehyde-lyase (cyanide-forming)|mandelonitrile benzaldehyde-lyase activity|hydroxynitrile lyase activity|D-oxynitrilase activity|(R)-oxynitrilase activity Catalysis of the reaction: mandelonitrile = cyanide + benzaldehyde. CHEBI:21241 vitamin C biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21241 GO:0046592 polyamine oxidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046592 MetaCyc:POLYAMINE-OXIDASE-RXN 1-N-acetylspermidine:oxygen oxidoreductase (deaminating)|N1-acetylspermidine:oxygen oxidoreductase (deaminating) Catalysis of the oxidative degradation or interconversion of polyamines. GO:0046591 obsolete embryonic leg joint morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046591 embryonic leg joint morphogenesis OBSOLETE. The process, occurring in the embryo, by which the anatomical structures of the leg joint are generated and organized. A leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner. GO:1900668 negative regulation of endocrocin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900668 downregulation of endocrocin biosynthesis|downregulation of endocrocin biosynthetic process|inhibition of endocrocin synthesis|inhibition of endocrocin formation|down-regulation of endocrocin biosynthesis|negative regulation of endocrocin biosynthesis|down-regulation of endocrocin anabolism|negative regulation of endocrocin anabolism|down-regulation of endocrocin biosynthetic process|negative regulation of endocrocin synthesis|down-regulation of endocrocin synthesis|down-regulation of endocrocin formation|inhibition of endocrocin biosynthetic process|negative regulation of endocrocin formation|downregulation of endocrocin anabolism|inhibition of endocrocin biosynthesis|down regulation of endocrocin anabolism|downregulation of endocrocin synthesis|downregulation of endocrocin formation|down regulation of endocrocin synthesis|down regulation of endocrocin biosynthesis|down regulation of endocrocin biosynthetic process|inhibition of endocrocin anabolism|down regulation of endocrocin formation Any process that stops, prevents or reduces the frequency, rate or extent of endocrocin biosynthetic process. GO:0046590 obsolete embryonic leg morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046590 embryonic leg morphogenesis OBSOLETE. The process, occurring in the embryo, by which the anatomical structures of the leg are generated and organized. A leg is a limb on which an animal walks and stands. UBERON:0002206 mammillary body biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002206 mammillary area|corpus mammillare|corpora mammillaria|corpus mamillare|corpus mamillare|corpora mamillaria|corpus mamillaris|MMB One of two hemispherical bulges on the base of the posterior hypothalamus (Butler and Hodos, Comparative Vertebrate Neuroanatomy, 2nd ed., 2005, pg 455). GO:1900667 regulation of endocrocin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900667 regulation of endocrocin anabolism|regulation of endocrocin synthesis|regulation of endocrocin formation|regulation of endocrocin biosynthesis Any process that modulates the frequency, rate or extent of endocrocin biosynthetic process. UBERON:0002209 fibrous joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002209 articulatio fibrosa|junctura fibrosa Nonsynovial joint in which the articulating bones or cartilages are connected by ligaments. Examples: sagittal suture, inferior tibiofibular syndesmosis, gomphosis.[FMA] GO:1900669 positive regulation of endocrocin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900669 upregulation of endocrocin formation|up-regulation of endocrocin anabolism|up regulation of endocrocin biosynthetic process|up regulation of endocrocin biosynthesis|activation of endocrocin biosynthetic process|positive regulation of endocrocin biosynthesis|up-regulation of endocrocin synthesis|activation of endocrocin anabolism|up-regulation of endocrocin formation|activation of endocrocin biosynthesis|activation of endocrocin synthesis|positive regulation of endocrocin anabolism|up regulation of endocrocin anabolism|activation of endocrocin formation|up-regulation of endocrocin biosynthesis|up-regulation of endocrocin biosynthetic process|positive regulation of endocrocin synthesis|up regulation of endocrocin synthesis|positive regulation of endocrocin formation|up regulation of endocrocin formation|upregulation of endocrocin biosynthetic process|upregulation of endocrocin anabolism|upregulation of endocrocin biosynthesis|upregulation of endocrocin synthesis Any process that activates or increases the frequency, rate or extent of endocrocin biosynthetic process. GO:1900664 regulation of emodin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900664 regulation of emodin biosynthesis|regulation of emodin anabolism|regulation of emodin synthesis|regulation of emodin formation Any process that modulates the frequency, rate or extent of emodin biosynthetic process. UBERON:0016855 ventral part of optic cup biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016855 ventral region of optic cup|ventral optic cup The ventral region of the optic cup that gives rise to the ventral part of the retina. RO:0004047 causally upstream of or within, positive effect biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0004047 RO:0004047 GO:1900663 positive regulation of emericellamide A biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900663 up regulation of emericellamide A anabolism|activation of emericellamide A formation|positive regulation of emericellamide A synthesis|up regulation of emericellamide A synthesis|upregulation of emericellamide A biosynthesis|upregulation of emericellamide A biosynthetic process|positive regulation of emericellamide A formation|up regulation of emericellamide A formation|upregulation of emericellamide A anabolism|up regulation of emericellamide A biosynthesis|up regulation of emericellamide A biosynthetic process|upregulation of emericellamide A synthesis|positive regulation of emericellamide A biosynthesis|activation of emericellamide A biosynthetic process|upregulation of emericellamide A formation|up-regulation of emericellamide A anabolism|activation of emericellamide A biosynthesis|up-regulation of emericellamide A synthesis|activation of emericellamide A anabolism|up-regulation of emericellamide A formation|up-regulation of emericellamide A biosynthesis|up-regulation of emericellamide A biosynthetic process|activation of emericellamide A synthesis|positive regulation of emericellamide A anabolism Any process that activates or increases the frequency, rate or extent of emericellamide A biosynthetic process. RO:0004046 causally upstream of or within, negative effect biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0004046 RO:0004046 UBERON:0016854 dorsal part of optic cup biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016854 dorsal region of optic cup|dorsal optic cup The dorsal region of the optic cup that gives rise to the dorsal part of the retina. GO:1900666 positive regulation of emodin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900666 up-regulation of emodin synthesis|activation of emodin anabolism|up-regulation of emodin formation|activation of emodin synthesis|positive regulation of emodin anabolism|up regulation of emodin biosynthetic process|up regulation of emodin biosynthesis|up regulation of emodin anabolism|activation of emodin formation|activation of emodin biosynthetic process|positive regulation of emodin synthesis|positive regulation of emodin biosynthesis|up regulation of emodin synthesis|positive regulation of emodin formation|activation of emodin biosynthesis|up regulation of emodin formation|upregulation of emodin anabolism|up-regulation of emodin biosynthesis|up-regulation of emodin biosynthetic process|upregulation of emodin synthesis|upregulation of emodin formation|up-regulation of emodin anabolism|upregulation of emodin biosynthesis|upregulation of emodin biosynthetic process Any process that activates or increases the frequency, rate or extent of emodin biosynthetic process. GO:1900665 negative regulation of emodin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900665 down regulation of emodin biosynthetic process|down regulation of emodin biosynthesis|negative regulation of emodin anabolism|down-regulation of emodin anabolism|downregulation of emodin biosynthesis|downregulation of emodin biosynthetic process|negative regulation of emodin synthesis|down-regulation of emodin synthesis|negative regulation of emodin formation|down-regulation of emodin formation|downregulation of emodin anabolism|down-regulation of emodin biosynthetic process|down-regulation of emodin biosynthesis|negative regulation of emodin biosynthesis|down regulation of emodin anabolism|downregulation of emodin synthesis|downregulation of emodin formation|down regulation of emodin synthesis|inhibition of emodin biosynthetic process|down regulation of emodin formation|inhibition of emodin anabolism|inhibition of emodin biosynthesis|inhibition of emodin synthesis|inhibition of emodin formation Any process that stops, prevents or reduces the frequency, rate or extent of emodin biosynthetic process. GO:0046599 regulation of centriole replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046599 Any process that modulates the frequency, rate or extent of the formation of a daughter centriole of an existing centriole. GO:1900660 positive regulation of emericellamide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900660 up regulation of emericellamide anabolism|activation of emericellamide formation|positive regulation of emericellamide synthesis|upregulation of emericellamide biosynthesis|upregulation of emericellamide biosynthetic process|up regulation of emericellamide synthesis|positive regulation of emericellamide formation|up regulation of emericellamide formation|upregulation of emericellamide anabolism|up regulation of emericellamide biosynthesis|up regulation of emericellamide biosynthetic process|activation of emericellamide biosynthetic process|positive regulation of emericellamide biosynthesis|upregulation of emericellamide synthesis|upregulation of emericellamide formation|up-regulation of emericellamide anabolism|activation of emericellamide biosynthesis|up-regulation of emericellamide synthesis|up-regulation of emericellamide biosynthetic process|activation of emericellamide anabolism|up-regulation of emericellamide biosynthesis|up-regulation of emericellamide formation|activation of emericellamide synthesis|positive regulation of emericellamide anabolism Any process that activates or increases the frequency, rate or extent of emericellamide biosynthetic process. GO:0046598 positive regulation of viral entry into host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046598 positive regulation of viral penetration into host cell Any process that activates or increases the frequency, rate or extent of the introduction of viral entry into the host cell. GO:0046597 negative regulation of viral entry into host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046597 negative regulation of viral penetration into host cell Any process that stops, prevents, or reduces the frequency, rate or extent of the entry of viral entry into a host cell. GO:1900662 negative regulation of emericellamide A biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900662 inhibition of emericellamide A biosynthesis|down-regulation of emericellamide A formation|negative regulation of emericellamide A formation|downregulation of emericellamide A anabolism|down regulation of emericellamide A biosynthesis|down regulation of emericellamide A anabolism|downregulation of emericellamide A synthesis|down regulation of emericellamide A biosynthetic process|downregulation of emericellamide A formation|downregulation of emericellamide A biosynthesis|downregulation of emericellamide A biosynthetic process|down regulation of emericellamide A synthesis|down regulation of emericellamide A formation|inhibition of emericellamide A anabolism|inhibition of emericellamide A synthesis|negative regulation of emericellamide A biosynthesis|down-regulation of emericellamide A biosynthesis|down-regulation of emericellamide A biosynthetic process|inhibition of emericellamide A formation|inhibition of emericellamide A biosynthetic process|down-regulation of emericellamide A anabolism|negative regulation of emericellamide A anabolism|down-regulation of emericellamide A synthesis|negative regulation of emericellamide A synthesis Any process that stops, prevents or reduces the frequency, rate or extent of emericellamide A biosynthetic process. GO:0046596 regulation of viral entry into host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046596 viral escort protein|regulation of viral penetration into host cell Any process that modulates the frequency, rate or extent of the viral entry into the host cell. GO:0046595 establishment of pole plasm mRNA localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046595 establishment of oocyte pole plasm mRNA localization|establishment of pole plasm mRNA localisation Any process that results in the directed movement of mRNA to the oocyte pole plasm. GO:1900661 regulation of emericellamide A biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900661 regulation of emericellamide A anabolism|regulation of emericellamide A synthesis|regulation of emericellamide A biosynthesis|regulation of emericellamide A formation Any process that modulates the frequency, rate or extent of emericellamide A biosynthetic process. GO:0071539 protein localization to centrosome biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071539 protein localisation to centrosome A process in which a protein is transported to, or maintained at, the centrosome. GO:0071538 obsolete SH2 domain-mediated complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071538 OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by an SH2 domain interaction. GO:0071537 obsolete C3HC4-type RING finger domain-mediated complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071537 zinc finger C3HC4 type domain-mediated complex assembly OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a C3HC4-type RING finger domain interaction. GO:0071536 obsolete RING-like zinc finger domain-mediated complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071536 RING-like domain-mediated complex assembly OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a RING-like zinc finger domain interaction. CHEBI:59836 oxo fatty acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59836 CHEBI:59835 hydroxy fatty acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59835 GO:0071535 RING-like zinc finger domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071535 Interacting selectively and non-covalently with a RING-like zinc finger domain domain of a protein. The RING-like domain is a zinc finger domain that is related to the C3HC4 RING finger domain. UBERON:0002213 cartilaginous joint biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002213 articulatio cartilaginea|junctura cartilaginea Nonsynovial joint in which the articulating bones or cartilages are connected by cartilage. Examples: Spheno-occipital synchondrosis, first sternocostal joint, pubic symphysis.[FMA] GO:0071534 obsolete zf-TRAF domain-mediated complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071534 zinc-finger-TRAF domain-mediated complex assembly|TRAF-type zinc finger domain-mediated complex assembly|zinc finger TRAF-type domain-mediated complex assembly OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a TRAF-type zinc finger (zf-TRAF) domain interaction. UBERON:0002216 symphysis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002216 secondary cartilaginous joint Cartilaginous joint in which the articulating bones or cartilages are connected by fibrocartilage. Examples: pubic symphysis, intervertebral symphysis, manubriosternal joint.[FMA] GO:0071533 obsolete ankyrin repeat-mediated complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071533 ANK repeat-mediated complex assembly OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by an ankyrin repeat interaction. UBERON:0002215 synchondrosis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002215 epiphysial cartilage|primary cartilaginous joint|cartilago epiphysialis Cartilaginous joint in which the articulating bones or cartilages are connected by hyaline cartilage. Examples: spheno-occipital synchondrosis, first sternocostal joint.[FMA] GO:0071532 ankyrin repeat binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071532 ANK repeat binding Interacting selectively and non-covalently with an ankyrin repeat of a protein. Ankyrin repeats are tandemly repeated modules of about 33 amino acids; each repeat folds into a helix-loop-helix structure with a beta-hairpin/loop region projecting out from the helices at a 90-degree angle, and repeats stack to form an L-shaped structure. UBERON:0002210 syndesmosis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002210 Fibrous joint in which the articulating bones or cartilages of the vertebral column and the limbs as well as articulating ossicles, are connected by skeletal ligaments or membranes. Examples: Intervertebral syndesmosis, inferior tibiofibular joint.[FMA] GO:0071531 obsolete Rel homology domain-mediated complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071531 RHD domain-mediated complex assembly OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a Rel homology domain (RHD) interaction. GO:0071530 obsolete FHA domain-mediated complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071530 forkhead-associated domain-mediated complex assembly OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by an FHA (forkhead-associated) domain interaction. CHEBI:35881 pnictogen hydride biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35881 UBERON:0002211 nerve root biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002211 radix nervi|initial segment of nerve A continuation of the neuron projection bundle component of a nerve inside, crossing or immediately outside the central nervous system. GO:0071561 nucleus-vacuole junction biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071561 nucleus-vacuole membrane contact site|NVJ|NV junction An organelle membrane contact site formed between the vacuole membrane and the outer nuclear membrane. In S. cerevisiae these contacts are mediated through direct physical interaction between Vac8p and Nvj1p. GO:0071560 cellular response to transforming growth factor beta stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071560 cellular response to TGF-beta stimulus|cellular response to TGFbeta stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus. GO:1900679 negative regulation of ferricrocin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900679 inhibition of ferricrocin biosynthetic process|inhibition of ferricrocin biosynthetic process, peptide modification|down regulation of ferricrocin biosynthetic process, peptide formation|negative regulation of ferricrocin synthesis|down-regulation of ferricrocin synthesis|negative regulation of ferricrocin formation|down-regulation of ferricrocin formation|downregulation of ferricrocin biosynthetic process, peptide formation|inhibition of ferricrocin biosynthesis|inhibition of ferricrocin anabolism|negative regulation of ferricrocin biosynthetic process, peptide modification|inhibition of ferricrocin synthesis|down-regulation of ferricrocin biosynthetic process, peptide modification|down-regulation of ferricrocin biosynthetic process, peptide formation|negative regulation of ferricrocin biosynthetic process, peptide formation|down regulation of ferricrocin anabolism|inhibition of ferricrocin formation|down-regulation of ferricrocin biosynthesis|down-regulation of ferricrocin biosynthetic process|negative regulation of ferricrocin biosynthesis|down regulation of ferricrocin synthesis|downregulation of ferricrocin anabolism|downregulation of ferricrocin biosynthetic process, peptide modification|down regulation of ferricrocin formation|downregulation of ferricrocin synthesis|downregulation of ferricrocin biosynthesis|downregulation of ferricrocin biosynthetic process|inhibition of ferricrocin biosynthetic process, peptide formation|down regulation of ferricrocin biosynthetic process, peptide modification|downregulation of ferricrocin formation|negative regulation of ferricrocin anabolism|down-regulation of ferricrocin anabolism|down regulation of ferricrocin biosynthetic process|down regulation of ferricrocin biosynthesis Any process that stops, prevents or reduces the frequency, rate or extent of ferricrocin biosynthetic process. GO:1900678 regulation of ferricrocin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900678 regulation of ferricrocin biosynthetic process, peptide formation|regulation of ferricrocin anabolism|regulation of ferricrocin synthesis|regulation of ferricrocin biosynthetic process, peptide modification|regulation of ferricrocin formation|regulation of ferricrocin biosynthesis Any process that modulates the frequency, rate or extent of ferricrocin biosynthetic process. CHEBI:21212 L-4'-bromophenylalanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21212 CHEBI:59826 progestin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59826 GO:1900675 regulation of F-9775B biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900675 regulation of F-9775B anabolism|regulation of F-9775B synthesis|regulation of F-9775B biosynthesis|regulation of F-9775B formation Any process that modulates the frequency, rate or extent of F-9775B biosynthetic process. RO:0004035 acts upstream of, negative effect biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0004035 RO:0004035 c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative GO:1900674 olefin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900674 olefin anabolism|olefin synthesis|olefin formation|olefin biosynthesis The chemical reactions and pathways resulting in the formation of olefin. GO:1900677 positive regulation of F-9775B biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900677 upregulation of F-9775B anabolism|positive regulation of F-9775B biosynthesis|up regulation of F-9775B biosynthesis|up regulation of F-9775B biosynthetic process|upregulation of F-9775B synthesis|upregulation of F-9775B formation|up regulation of F-9775B anabolism|positive regulation of F-9775B anabolism|upregulation of F-9775B biosynthetic process|upregulation of F-9775B biosynthesis|up regulation of F-9775B synthesis|positive regulation of F-9775B synthesis|activation of F-9775B anabolism|up regulation of F-9775B formation|positive regulation of F-9775B formation|activation of F-9775B synthesis|up-regulation of F-9775B biosynthetic process|up-regulation of F-9775B biosynthesis|up-regulation of F-9775B anabolism|activation of F-9775B formation|activation of F-9775B biosynthetic process|up-regulation of F-9775B synthesis|activation of F-9775B biosynthesis|up-regulation of F-9775B formation Any process that activates or increases the frequency, rate or extent of F-9775B biosynthetic process. GO:1900676 negative regulation of F-9775B biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900676 inhibition of F-9775B synthesis|down regulation of F-9775B anabolism|inhibition of F-9775B formation|downregulation of F-9775B biosynthetic process|downregulation of F-9775B anabolism|down regulation of F-9775B synthesis|downregulation of F-9775B biosynthesis|down regulation of F-9775B formation|downregulation of F-9775B synthesis|down regulation of F-9775B biosynthetic process|down regulation of F-9775B biosynthesis|inhibition of F-9775B biosynthetic process|downregulation of F-9775B formation|down-regulation of F-9775B anabolism|negative regulation of F-9775B anabolism|inhibition of F-9775B biosynthesis|down-regulation of F-9775B synthesis|negative regulation of F-9775B synthesis|down-regulation of F-9775B formation|negative regulation of F-9775B formation|inhibition of F-9775B anabolism|negative regulation of F-9775B biosynthesis|down-regulation of F-9775B biosynthesis|down-regulation of F-9775B biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of F-9775B biosynthetic process. GO:1900671 negative regulation of F-9775A biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900671 inhibition of F-9775A formation|down regulation of F-9775A anabolism|downregulation of F-9775A biosynthetic process|downregulation of F-9775A biosynthesis|down regulation of F-9775A synthesis|downregulation of F-9775A anabolism|down regulation of F-9775A biosynthetic process|down regulation of F-9775A biosynthesis|down regulation of F-9775A formation|inhibition of F-9775A biosynthetic process|downregulation of F-9775A synthesis|downregulation of F-9775A formation|inhibition of F-9775A biosynthesis|down-regulation of F-9775A anabolism|negative regulation of F-9775A anabolism|down-regulation of F-9775A synthesis|negative regulation of F-9775A synthesis|down-regulation of F-9775A formation|negative regulation of F-9775A formation|inhibition of F-9775A anabolism|down-regulation of F-9775A biosynthesis|negative regulation of F-9775A biosynthesis|down-regulation of F-9775A biosynthetic process|inhibition of F-9775A synthesis Any process that stops, prevents or reduces the frequency, rate or extent of F-9775A biosynthetic process. RO:0004032 acts upstream of or within, positive effect biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0004032 RO:0004032 GO:1900670 regulation of F-9775A biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900670 regulation of F-9775A anabolism|regulation of F-9775A biosynthesis|regulation of F-9775A synthesis|regulation of F-9775A formation Any process that modulates the frequency, rate or extent of F-9775A biosynthetic process. RO:0004031 enables subfunction biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0004031 RO:0004031 Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P. GO:1900673 olefin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900673 olefin metabolism The chemical reactions and pathways involving olefin. RO:0004034 acts upstream of, positive effect biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0004034 RO:0004034 c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive GO:1900672 positive regulation of F-9775A biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900672 up regulation of F-9775A biosynthetic process|up regulation of F-9775A biosynthesis|upregulation of F-9775A synthesis|upregulation of F-9775A formation|up regulation of F-9775A anabolism|upregulation of F-9775A biosynthetic process|upregulation of F-9775A biosynthesis|positive regulation of F-9775A anabolism|up regulation of F-9775A synthesis|positive regulation of F-9775A synthesis|activation of F-9775A anabolism|up regulation of F-9775A formation|positive regulation of F-9775A formation|up-regulation of F-9775A biosynthesis|activation of F-9775A synthesis|activation of F-9775A biosynthetic process|up-regulation of F-9775A biosynthetic process|up-regulation of F-9775A anabolism|activation of F-9775A formation|activation of F-9775A biosynthesis|up-regulation of F-9775A synthesis|up-regulation of F-9775A formation|positive regulation of F-9775A biosynthesis|upregulation of F-9775A anabolism Any process that activates or increases the frequency, rate or extent of F-9775A biosynthetic process. RO:0004033 acts upstream of or within, negative effect biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0004033 RO:0004033 CHEBI:35850 sulfone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35850 UBERON:0002285 telencephalic ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002285 forebrain ventricle|lateral ventricle of brain|telencephalic ventricles|tectal ventricle|telencephalic vesicle|telencephalic ventricle|telencephalon lateral ventricle|lateral ventricles|lateral ventricle A brain ventricle that is part of a telencephalon. In mammals and species with an evaginated telencephalon, this is one of a pair of lateral structures, one in each hemisphere GO:1900680 positive regulation of ferricrocin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900680 up-regulation of ferricrocin biosynthetic process, peptide formation|positive regulation of ferricrocin biosynthesis|up regulation of ferricrocin anabolism|up regulation of ferricrocin biosynthesis|up regulation of ferricrocin biosynthetic process|positive regulation of ferricrocin anabolism|up regulation of ferricrocin synthesis|positive regulation of ferricrocin synthesis|upregulation of ferricrocin biosynthetic process, peptide modification|up regulation of ferricrocin formation|upregulation of ferricrocin biosynthetic process, peptide formation|activation of ferricrocin anabolism|positive regulation of ferricrocin formation|upregulation of ferricrocin biosynthesis|upregulation of ferricrocin biosynthetic process|activation of ferricrocin synthesis|up-regulation of ferricrocin anabolism|activation of ferricrocin formation|up-regulation of ferricrocin biosynthetic process, peptide modification|up-regulation of ferricrocin synthesis|up regulation of ferricrocin biosynthetic process, peptide formation|up-regulation of ferricrocin biosynthetic process|positive regulation of ferricrocin biosynthetic process, peptide formation|up-regulation of ferricrocin biosynthesis|up-regulation of ferricrocin formation|activation of ferricrocin biosynthetic process|activation of ferricrocin biosynthetic process, peptide modification|upregulation of ferricrocin anabolism|activation of ferricrocin biosynthetic process, peptide formation|activation of ferricrocin biosynthesis|upregulation of ferricrocin synthesis|positive regulation of ferricrocin biosynthetic process, peptide modification|up regulation of ferricrocin biosynthetic process, peptide modification|upregulation of ferricrocin formation Any process that activates or increases the frequency, rate or extent of ferricrocin biosynthetic process. CHEBI:35856 lipoxygenase inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35856 UBERON:0002280 otolith biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002280 immature otolith|statoconium|statoconia|otoliths|otoconial crystal|otoconia|otoconium|statolith|immature otoliths Acellular structure composed of calcium carbonate located in the otolith organ. CHEBI:59825 CMP-3-deoxy-alpha-D-manno-octulosonate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59825 GO:0071569 protein ufmylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071569 Covalent attachment of the ubiquitin-like protein UFM1 to another protein. CHEBI:21217 L-alaninamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21217 GO:0071568 UFM1 transferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071568 Catalysis of the transfer of UFM1 from one protein to another via the reaction X-UFM1 + Y --> Y-UFM1 + X, where both X-UFM1 and Y-UFM1 are covalent linkages. GO:0071567 UFM1 hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071567 Catalysis of the hydrolysis of UFM1, a small ubiquitin-related modifier, from previously modified substrates. GO:0071566 UFM1 activating enzyme activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071566 Catalysis of the activation of the small ubiquitin-related modifier UFM1, through the formation of an ATP-dependent high-energy thiolester bond. GO:0071565 nBAF complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071565 A SWI/SNF-type complex that is found in post-mitotic neurons, and in human contains actin and proteins encoded by the ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, DPF1/BAF45B, DPF3/BAF45C, ACTL6B/BAF53B genes. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth. GO:0071564 npBAF complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071564 A SWI/SNF-type complex that is found in neural stem or progenitor cells, and in human contains actin and proteins encoded by the ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, PHF10/BAF45A, ACTL6A/BAF53A genes. The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. UBERON:0002286 third ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002286 ventriculus diencephali|ventriculus tertius cerebri|diencephalic ventricle|3rd ventricle|diencephalic vesicle Part of the ventricular system of the brain, forming a single large cavity in the midline of the diencephalon; it is continuous with the lateral ventricles through the interventricular foramen and the fourth ventricle through the cerebral aqueduct. (Maryann Martone) GO:0071563 Myo2p-Vac17p-Vac8p transport complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071563 A protein complex that is involved in transport of vacuoles to a newly formed daughter cell. In yeast, this complex is composed of Myo2p, Vac17p, and Vac8p. UBERON:0002288 choroid plexus of third ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002288 chorioid plexus of cerebral hemisphere of third ventricle|choroid plexus third ventricle|diencephalic choroid plexus|third ventricle choroid plexus|third ventricle chorioid plexus of cerebral hemisphere|3rd ventricle choroid plexus|chorioid plexus of third ventricle Part of choroid plexus contained in the third ventricle GO:0071562 nucleus-vacuole junction assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071562 NVJ formation|NV junction formation|nucleus-vacuole junction formation|NV junction assembly|NVJ assembly The aggregation, arrangement and bonding together of a set of components to form a nucleus-vacuole junction, which are membrane contact sites formed between the vacuole membrane and the outer nuclear membrane. In S. cerevisiae these contacts are mediated through direct physical interaction between Vac8p and Nvj1p. GO:0071550 death-inducing signaling complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071550 DD-mediated complex assembly|DISC assembly|death domain-mediated complex assembly involved in extrinsic apoptotic pathway|death domain-mediated complex assembly|death-inducing signaling complex formation|death-inducing signalling complex assembly|DISC formation A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a death domain (DD) interaction, as part of the extrinsic apoptotic signaling pathway. GO:1900689 regulation of gliotoxin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900689 regulation of gliotoxin synthesis|regulation of gliotoxin formation|regulation of gliotoxin biosynthesis|regulation of gliotoxin anabolism Any process that modulates the frequency, rate or extent of gliotoxin biosynthetic process. CHEBI:59815 2,3,5,6-tetrachlorophenolate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59815 GO:1900686 regulation of gerfelin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900686 regulation of gerfelin anabolism|regulation of gerfelin synthesis|regulation of gerfelin formation|regulation of gerfelin biosynthesis Any process that modulates the frequency, rate or extent of gerfelin biosynthetic process. GO:1900685 positive regulation of fumonisin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900685 upregulation of fumonisin anabolism|upregulation of fumonisin synthesis|upregulation of fumonisin formation|upregulation of fumonisin biosynthesis|upregulation of fumonisin biosynthetic process|up regulation of fumonisin anabolism|positive regulation of fumonisin anabolism|up regulation of fumonisin synthesis|positive regulation of fumonisin synthesis|up regulation of fumonisin formation|up-regulation of fumonisin biosynthesis|activation of fumonisin anabolism|up-regulation of fumonisin biosynthetic process|activation of fumonisin biosynthetic process|positive regulation of fumonisin formation|activation of fumonisin synthesis|up-regulation of fumonisin anabolism|activation of fumonisin biosynthesis|activation of fumonisin formation|up-regulation of fumonisin synthesis|positive regulation of fumonisin biosynthesis|up-regulation of fumonisin formation|up regulation of fumonisin biosynthesis|up regulation of fumonisin biosynthetic process Any process that activates or increases the frequency, rate or extent of fumonisin biosynthetic process. CHEBI:35868 hydroxy monocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35868 GO:1900688 positive regulation of gerfelin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900688 up-regulation of gerfelin synthesis|up regulation of gerfelin biosynthetic process|up regulation of gerfelin biosynthesis|activation of gerfelin anabolism|activation of gerfelin biosynthetic process|up-regulation of gerfelin formation|positive regulation of gerfelin biosynthesis|activation of gerfelin synthesis|positive regulation of gerfelin anabolism|activation of gerfelin biosynthesis|activation of gerfelin formation|up regulation of gerfelin anabolism|positive regulation of gerfelin synthesis|up regulation of gerfelin synthesis|positive regulation of gerfelin formation|up-regulation of gerfelin biosynthesis|up-regulation of gerfelin biosynthetic process|up regulation of gerfelin formation|upregulation of gerfelin anabolism|upregulation of gerfelin biosynthesis|upregulation of gerfelin synthesis|upregulation of gerfelin biosynthetic process|upregulation of gerfelin formation|up-regulation of gerfelin anabolism Any process that activates or increases the frequency, rate or extent of gerfelin biosynthetic process. GO:1900687 negative regulation of gerfelin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900687 down-regulation of gerfelin anabolism|negative regulation of gerfelin anabolism|down-regulation of gerfelin biosynthesis|down-regulation of gerfelin biosynthetic process|down-regulation of gerfelin synthesis|negative regulation of gerfelin synthesis|negative regulation of gerfelin biosynthesis|down-regulation of gerfelin formation|negative regulation of gerfelin formation|downregulation of gerfelin anabolism|inhibition of gerfelin biosynthetic process|downregulation of gerfelin synthesis|down regulation of gerfelin anabolism|inhibition of gerfelin biosynthesis|downregulation of gerfelin formation|down regulation of gerfelin synthesis|inhibition of gerfelin anabolism|down regulation of gerfelin formation|down regulation of gerfelin biosynthesis|down regulation of gerfelin biosynthetic process|inhibition of gerfelin synthesis|inhibition of gerfelin formation|downregulation of gerfelin biosynthetic process|downregulation of gerfelin biosynthesis Any process that stops, prevents or reduces the frequency, rate or extent of gerfelin biosynthetic process. GO:1900682 octadecene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900682 octadecene anabolism|octadecene biosynthesis|octadecene synthesis|octadecene formation|1-octadecene biosynthetic process The chemical reactions and pathways resulting in the formation of octadecene. GO:1900681 octadecene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900681 octadecene metabolism The chemical reactions and pathways involving octadecene. GO:1900684 negative regulation of fumonisin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900684 inhibition of fumonisin synthesis|downregulation of fumonisin biosynthesis|downregulation of fumonisin biosynthetic process|inhibition of fumonisin formation|down regulation of fumonisin anabolism|down regulation of fumonisin biosynthesis|down regulation of fumonisin biosynthetic process|inhibition of fumonisin biosynthetic process|downregulation of fumonisin anabolism|down regulation of fumonisin synthesis|down regulation of fumonisin formation|downregulation of fumonisin synthesis|inhibition of fumonisin biosynthesis|downregulation of fumonisin formation|down-regulation of fumonisin anabolism|negative regulation of fumonisin anabolism|down-regulation of fumonisin synthesis|negative regulation of fumonisin synthesis|down-regulation of fumonisin formation|negative regulation of fumonisin formation|down-regulation of fumonisin biosynthetic process|down-regulation of fumonisin biosynthesis|negative regulation of fumonisin biosynthesis|inhibition of fumonisin anabolism Any process that stops, prevents or reduces the frequency, rate or extent of fumonisin biosynthetic process. GO:1900683 regulation of fumonisin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900683 regulation of fumonisin biosynthesis|regulation of fumonisin anabolism|regulation of fumonisin synthesis|regulation of fumonisin formation Any process that modulates the frequency, rate or extent of fumonisin biosynthetic process. UBERON:0002272 medial zone of hypothalamus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002272 medial zone of the hypothalamus|hypothalamic medial zone behavioral control column|zona medialis hypothalamicae|hypothalamus medial zone GO:1900691 positive regulation of gliotoxin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900691 up-regulation of gliotoxin formation|upregulation of gliotoxin biosynthetic process|upregulation of gliotoxin biosynthesis|upregulation of gliotoxin anabolism|upregulation of gliotoxin synthesis|activation of gliotoxin biosynthetic process|up-regulation of gliotoxin biosynthetic process|upregulation of gliotoxin formation|up-regulation of gliotoxin biosynthesis|up regulation of gliotoxin anabolism|positive regulation of gliotoxin anabolism|activation of gliotoxin biosynthesis|up regulation of gliotoxin synthesis|positive regulation of gliotoxin synthesis|activation of gliotoxin anabolism|up regulation of gliotoxin formation|positive regulation of gliotoxin biosynthesis|positive regulation of gliotoxin formation|up regulation of gliotoxin biosynthetic process|up regulation of gliotoxin biosynthesis|activation of gliotoxin synthesis|up-regulation of gliotoxin anabolism|activation of gliotoxin formation|up-regulation of gliotoxin synthesis Any process that activates or increases the frequency, rate or extent of gliotoxin biosynthetic process. GO:1900690 negative regulation of gliotoxin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900690 inhibition of gliotoxin synthesis|inhibition of gliotoxin biosynthesis|down regulation of gliotoxin anabolism|inhibition of gliotoxin formation|downregulation of gliotoxin anabolism|down regulation of gliotoxin synthesis|down regulation of gliotoxin formation|downregulation of gliotoxin synthesis|negative regulation of gliotoxin biosynthesis|downregulation of gliotoxin formation|down-regulation of gliotoxin biosynthetic process|down-regulation of gliotoxin biosynthesis|down-regulation of gliotoxin anabolism|negative regulation of gliotoxin anabolism|down-regulation of gliotoxin synthesis|negative regulation of gliotoxin synthesis|downregulation of gliotoxin biosynthetic process|down-regulation of gliotoxin formation|negative regulation of gliotoxin formation|downregulation of gliotoxin biosynthesis|down regulation of gliotoxin biosynthetic process|down regulation of gliotoxin biosynthesis|inhibition of gliotoxin anabolism|inhibition of gliotoxin biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of gliotoxin biosynthetic process. CHEBI:35862 bacitracin A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35862 CHEBI:35865 5alpha-cholest-7-ene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35865 GO:0071559 response to transforming growth factor beta biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071559 response to TGF-beta stimulus|response to TGFbeta stimulus|response to transforming growth factor beta stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus. GO:0071558 histone demethylase activity (H3-K27 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071558 Reactome:R-HSA-5617887|EC:1.14.11.68|Reactome:R-HSA-3222593|Reactome:R-HSA-5617431 Catalysis of the removal of a methyl group from lysine at position 27 of the histone H3 protein. CHEBI:59814 L-alpha-amino acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59814 GO:0071557 histone H3-K27 demethylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071557 H3K27 demethylation The modification of histone H3 by the removal of a methyl group from lysine at position 27 of the histone. GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071556 integral to lumenal side of endoplasmic reticulum membrane|integral to lumenal leaflet of endoplasmic reticulum membrane|integral to ER membrane, lumenal side|integral to lumenal side of ER membrane The component of the endoplasmic reticulum membrane consisting of the gene products that penetrate only the lumenal side of the membrane. GO:0071555 cell wall organization biolink:BiologicalProcess go-plus goslim_candida|goslim_pir http://purl.obolibrary.org/obo/GO_0071555 cell wall organization at cellular level|cellular cell wall organization|cell wall organization and biogenesis|cell wall organisation|cell wall organisation in other organism|cell wall organization in other organism|cellular cell wall organisation A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. GO:0071554 cell wall organization or biogenesis biolink:BiologicalProcess go-plus goslim_generic|goslim_pombe|goslim_chembl|goslim_yeast http://purl.obolibrary.org/obo/GO_0071554 cellular cell wall organisation or biogenesis|cell wall organization or biogenesis at cellular level|cellular cell wall organization or biogenesis|cell wall organisation or biogenesis A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cell wall. GO:0071553 G protein-coupled pyrimidinergic nucleotide receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071553 pyrimidinergic nucleotide receptor activity, G-protein coupled|pyrimidinergic nucleotide receptor activity, G protein coupled|G-protein coupled pyrimidinergic nucleotide receptor activity|G protein coupled pyrimidinergic nucleotide receptor activity Combining with a pyrimidine nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. UBERON:0002275 reticular formation biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002275 brainstem reticular formation|reticular formation of the brainstem|reticular formation (classical)|brain stem reticular formation A composite substructure of the brainstem that consists of the midbrain reticular formation, the pontine reticular formation and the medullary reticular formation ( Carpenter-1983 ). GO:0071552 obsolete RIP homotypic interaction motif-mediated complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071552 RHIM-mediated complex assembly OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a RIP homotypic interaction motif (RHIM) interaction. GO:0071551 RIP homotypic interaction motif binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071551 RHIM binding Interacting selectively and non-covalently with a RIP homotypic interaction motif (RHIM) of a protein. The RHIM is a 16-amino-acid motif found in some members, including RIP3, of a family of related kinases. GO:0071583 negative regulation of zinc ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071583 negative regulation of zinc ion membrane transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of zinc ions (Zn2+) from one side of a membrane to the other. GO:0071582 negative regulation of zinc ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071582 Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of zinc ions (Zn2+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:59809 docetaxel trihydrate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59809 GO:0071581 regulation of zinc ion transmembrane import biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071581 Any process that modulates the frequency, rate or extent of zinc ion import. GO:0071580 regulation of zinc ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071580 regulation of zinc ion membrane transport Any process that modulates the frequency, rate or extent of the directed movement of zinc ions (Zn2+) from one side of a membrane to the other. CHEBI:59807 (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59807 CHEBI:59806 (S)-nicotinium(1+) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59806 GO:1900697 positive regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900697 upregulation of N',N'',N'''-triacetylfusarinine C biosynthetic process|upregulation of N',N'',N'''-triacetylfusarinine C biosynthesis|up-regulation of N',N'',N'''-triacetylfusarinine C synthesis|up-regulation of N',N'',N'''-triacetylfusarinine C formation|upregulation of N',N'',N'''-triacetylfusarinine C anabolism|up-regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process|up-regulation of N',N'',N'''-triacetylfusarinine C biosynthesis|activation of N',N'',N'''-triacetylfusarinine C biosynthetic process|upregulation of N',N'',N'''-triacetylfusarinine C synthesis|upregulation of N',N'',N'''-triacetylfusarinine C formation|activation of N',N'',N'''-triacetylfusarinine C biosynthesis|up regulation of N',N'',N'''-triacetylfusarinine C anabolism|positive regulation of N',N'',N'''-triacetylfusarinine C anabolism|positive regulation of N',N'',N'''-triacetylfusarinine C biosynthesis|up regulation of N',N'',N'''-triacetylfusarinine C synthesis|positive regulation of N',N'',N'''-triacetylfusarinine C synthesis|up regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process|up regulation of N',N'',N'''-triacetylfusarinine C biosynthesis|activation of N',N'',N'''-triacetylfusarinine C anabolism|up regulation of N',N'',N'''-triacetylfusarinine C formation|positive regulation of N',N'',N'''-triacetylfusarinine C formation|activation of N',N'',N'''-triacetylfusarinine C synthesis|up-regulation of N',N'',N'''-triacetylfusarinine C anabolism|activation of N',N'',N'''-triacetylfusarinine C formation Any process that activates or increases the frequency, rate or extent of N',N'',N'''-triacetylfusarinine C biosynthetic process. GO:1900696 negative regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900696 inhibition of N',N'',N'''-triacetylfusarinine C anabolism|inhibition of N',N'',N'''-triacetylfusarinine C biosynthesis|inhibition of N',N'',N'''-triacetylfusarinine C synthesis|down regulation of N',N'',N'''-triacetylfusarinine C anabolism|inhibition of N',N'',N'''-triacetylfusarinine C formation|down regulation of N',N'',N'''-triacetylfusarinine C synthesis|downregulation of N',N'',N'''-triacetylfusarinine C anabolism|down-regulation of N',N'',N'''-triacetylfusarinine C biosynthesis|negative regulation of N',N'',N'''-triacetylfusarinine C biosynthesis|down regulation of N',N'',N'''-triacetylfusarinine C formation|down-regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process|downregulation of N',N'',N'''-triacetylfusarinine C synthesis|downregulation of N',N'',N'''-triacetylfusarinine C formation|down-regulation of N',N'',N'''-triacetylfusarinine C anabolism|negative regulation of N',N'',N'''-triacetylfusarinine C anabolism|downregulation of N',N'',N'''-triacetylfusarinine C biosynthesis|downregulation of N',N'',N'''-triacetylfusarinine C biosynthetic process|down-regulation of N',N'',N'''-triacetylfusarinine C synthesis|negative regulation of N',N'',N'''-triacetylfusarinine C synthesis|down-regulation of N',N'',N'''-triacetylfusarinine C formation|down regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process|negative regulation of N',N'',N'''-triacetylfusarinine C formation|down regulation of N',N'',N'''-triacetylfusarinine C biosynthesis|inhibition of N',N'',N'''-triacetylfusarinine C biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of N',N'',N'''-triacetylfusarinine C biosynthetic process. GO:1900699 negative regulation of o-orsellinic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900699 down-regulation of o-orsellinic acid anabolism|negative regulation of o-orsellinic acid anabolism|down-regulation of o-orsellinic acid synthesis|negative regulation of o-orsellinic acid synthesis|negative regulation of o-orsellinic acid biosynthesis|down-regulation of o-orsellinic acid biosynthesis|down-regulation of o-orsellinic acid biosynthetic process|down-regulation of o-orsellinic acid formation|negative regulation of o-orsellinic acid formation|inhibition of o-orsellinic acid anabolism|downregulation of o-orsellinic acid biosynthesis|downregulation of o-orsellinic acid biosynthetic process|inhibition of o-orsellinic acid synthesis|down regulation of o-orsellinic acid anabolism|down regulation of o-orsellinic acid biosynthetic process|down regulation of o-orsellinic acid biosynthesis|inhibition of o-orsellinic acid formation|inhibition of o-orsellinic acid biosynthetic process|down regulation of o-orsellinic acid synthesis|downregulation of o-orsellinic acid anabolism|inhibition of o-orsellinic acid biosynthesis|down regulation of o-orsellinic acid formation|downregulation of o-orsellinic acid synthesis|downregulation of o-orsellinic acid formation Any process that stops, prevents or reduces the frequency, rate or extent of o-orsellinic acid biosynthetic process. GO:1900698 regulation of o-orsellinic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900698 regulation of o-orsellinic acid biosynthesis|regulation of o-orsellinic acid anabolism|regulation of o-orsellinic acid synthesis|regulation of o-orsellinic acid formation Any process that modulates the frequency, rate or extent of o-orsellinic acid biosynthetic process. GO:1900693 negative regulation of (+)-kotanin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900693 inhibition of (+)-kotanin formation|down regulation of (+)-kotanin biosynthetic process|down regulation of (+)-kotanin anabolism|down regulation of (+)-kotanin biosynthesis|inhibition of (+)-kotanin biosynthetic process|downregulation of (+)-kotanin anabolism|down regulation of (+)-kotanin synthesis|inhibition of (+)-kotanin biosynthesis|down regulation of (+)-kotanin formation|downregulation of (+)-kotanin synthesis|downregulation of (+)-kotanin formation|down-regulation of (+)-kotanin anabolism|negative regulation of (+)-kotanin anabolism|down-regulation of (+)-kotanin synthesis|negative regulation of (+)-kotanin synthesis|negative regulation of (+)-kotanin biosynthesis|down-regulation of (+)-kotanin biosynthetic process|down-regulation of (+)-kotanin biosynthesis|down-regulation of (+)-kotanin formation|negative regulation of (+)-kotanin formation|inhibition of (+)-kotanin anabolism|downregulation of (+)-kotanin biosynthesis|downregulation of (+)-kotanin biosynthetic process|inhibition of (+)-kotanin synthesis Any process that stops, prevents or reduces the frequency, rate or extent of (+)-kotanin biosynthetic process. GO:1900692 regulation of (+)-kotanin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900692 regulation of (+)-kotanin anabolism|regulation of (+)-kotanin synthesis|regulation of (+)-kotanin formation|regulation of (+)-kotanin biosynthesis Any process that modulates the frequency, rate or extent of (+)-kotanin biosynthetic process. GO:1900695 regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900695 regulation of N',N'',N'''-triacetylfusarinine C anabolism|regulation of N',N'',N'''-triacetylfusarinine C synthesis|regulation of N',N'',N'''-triacetylfusarinine C formation|regulation of N',N'',N'''-triacetylfusarinine C biosynthesis Any process that modulates the frequency, rate or extent of N',N'',N'''-triacetylfusarinine C biosynthetic process. GO:1900694 positive regulation of (+)-kotanin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900694 upregulation of (+)-kotanin synthesis|upregulation of (+)-kotanin biosynthetic process|upregulation of (+)-kotanin biosynthesis|upregulation of (+)-kotanin formation|up regulation of (+)-kotanin anabolism|positive regulation of (+)-kotanin anabolism|up regulation of (+)-kotanin synthesis|up-regulation of (+)-kotanin biosynthetic process|up-regulation of (+)-kotanin biosynthesis|activation of (+)-kotanin biosynthetic process|positive regulation of (+)-kotanin synthesis|up regulation of (+)-kotanin formation|activation of (+)-kotanin anabolism|positive regulation of (+)-kotanin formation|activation of (+)-kotanin synthesis|activation of (+)-kotanin biosynthesis|up-regulation of (+)-kotanin anabolism|activation of (+)-kotanin formation|positive regulation of (+)-kotanin biosynthesis|up-regulation of (+)-kotanin synthesis|up regulation of (+)-kotanin biosynthetic process|up regulation of (+)-kotanin biosynthesis|up-regulation of (+)-kotanin formation|upregulation of (+)-kotanin anabolism Any process that activates or increases the frequency, rate or extent of (+)-kotanin biosynthetic process. UBERON:0002261 dorsal root of spinal cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002261 dorsal roots|posterior root of spinal nerve|sensory root of spinal nerve|radix posterior nervi spinalis|dorsal spinal nerve root|radix sensoria (nervus spinalis)|radix posterior|radix dorsalis|radix posterior (nervus spinalis)|root sensoria nervi spinalis|root dorsali nervi spinalis|sensory spinal root|dorsal spinal root|dorsal root|dorsal root of spinal nerve The dorsal roots contain afferent sensory axons. The dorsal roots of each side continue outwards, along the way forming a dorsal root ganglion (also called a spinal ganglion). UBERON:0002263 lentiform nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002263 nucleus lentiformis|nucleus lenticularis|lenticular nucleus|nucleus lentiformis The lentiform nucleus or lenticular nucleus comprises the putamen and the globus pallidus within the basal ganglia. It is a large, cone-shaped mass of gray matter just lateral to the internal capsule. [WP,unvetted]. RO:0004007 has primary input or output biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0004007 RO:0004007 p 'has primary input ot output' c iff either (a) p 'has primary input' c or (b) p 'has primary output' c. RO:0004009 has primary input biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0004009 RO:0004009 p has primary input c if (a) p has input c and (b) the goal of process is to modify, consume, or transform c. RO:0004008 has primary output biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/RO_0004008 RO:0004008 p has primary output c if (a) p has output c and (b) the goal of process is to modify, produce, or transform c. UBERON:0002268 olfactory organ biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002268 olfactory neuroepithelium|primary olfactory organ|olfactory organ|main olfactory organ|olfactory sensory organ|organum olfactorium|organ olfactus|olfactory sense organ An organ that houses olfactory neurons and is responsible for the sense of smell. Examples include the vertebrate nose and the Drosophila dorsal organ. GO:0071589 pyridine nucleoside biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071589 pyridine nucleoside anabolism|pyridine nucleoside synthesis|pyridine nucleoside formation|pyridine nucleoside biosynthesis The chemical reactions and pathways resulting in the formation of any pyridine nucleoside, one of a family of organic molecules consisting of a pyridine base covalently bonded to a sugar, usually ribose. GO:0071588 hydrogen peroxide mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071588 H2O2 mediated signaling pathway|hydrogen peroxide mediated signalling pathway A series of molecular signals mediated by the detection of hydrogen peroxide (H2O2). UBERON:0002265 olfactory tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002265 tractus olfactorius|olfactory stalk|tractus olfactorium|olfactory peduncle|pedunclulus olfactorius White matter tract that contains projections from the olfactory bulb to other parts of the brain GO:0071587 CAAX-box protein modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071587 The covalent alteration of one or more amino acid residues within the CAAX box region of CAAX box proteins. GO:0071586 CAAX-box protein processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071586 The second process in a series of specific posttranslational modifications to the CAAX box region of CAAX box proteins, in which the last three amino acids of the protein (AAX) are removed by proteolysis. UBERON:0002264 olfactory bulb biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002264 bulbus olfactorius (Morgagni)|bulbus olfactorius|bulbus olfactorius|olfactory lobe|olfactory lobe (Barr & Kiernan) A bulbous anterior projection of the olfactory lobe that is the place of termination of the olfactory nerves and is especially well developed in lower vertebrates (as fishes)[BTO]. GO:0071585 detoxification of cadmium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071585 Any process that reduces or removes the toxicity of cadmium ion. These may include transport of cadmium away from sensitive areas and to compartments or complexes whose purpose is sequestration of cadmium ion. GO:0071584 negative regulation of zinc ion transmembrane import biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071584 Any process that stops, prevents, or reduces the frequency, rate or extent of zinc ion import. GO:0071572 histone H3-K56 deacetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071572 The modification of histone H3 by the removal of an acetyl group from lysine at position 56 of the histone. GO:0071571 obsolete LRR domain-mediated complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071571 leucine-rich repeat domain-mediated complex assembly OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by an LRR (leucine-rich repeat) domain interaction. GO:0071570 cement gland development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071570 The process whose specific outcome is the progression of the cement gland over time, from its formation to the mature structure. The cement gland is a simple mucus-secreting organ positioned at the anterior of amphibious embryos. The cement gland attaches the newly hatched embryo to a support before the hatchling can swim well or feed. CHEBI:21203 L-2-aminohexanoate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21203 CHEBI:11893 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_11893 CHEBI:11892 N-carbamoyl-beta-alaninate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_11892 CHEBI:35842 antirheumatic drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35842 UBERON:0002258 dorsal funiculus of spinal cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002258 posterior funiculus of spinal cord|posterior white column of spinal cord|funiculus posterior medullae spinalis|funiculus dorsalis|dorsal white column of spinal cord|posterior funiculus|dorsal funiculus|dorsal funiculus of spinal cord the white substance of the spinal cord lying on either side between the posterior median sulcus and the dorsal root. UBERON:0002257 ventral horn of spinal cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002257 ventral region of spinal cord|spinal cord anterior horn|columna grisea anterior medullae spinalis|anterior grey column of spinal cord|ventral horn of the spinal cord|ventral spinal cord|anterior column|anterior column of the spinal cord|anterior gray horn of spinal cord|ventral gray column of spinal cord|ventral horn spinal cord|ventral grey horn|anterior horn|cornu anterius medullae spinalis|spinal cord ventral horn|ventral grey column of spinal cord|anterior horn (spinal cord)|ventral horns spinal cord|ventral gray matter of spinal cord|anterior gray column of spinal cord The ventral grey column of the spinal cord[MP]. The neurons of the ventral region of the mature spinal cord participate in motor output[GO]. GO:0071579 regulation of zinc ion transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071579 Any process that modulates the frequency, rate or extent of the directed movement of zinc ions (Zn2+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0071578 zinc ion import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071578 zinc import|zinc uptake|zinc ion transmembrane import|high-affinity zinc II ion transmembrane import|low-affinity zinc II ion transport|zinc II ion plasma membrane import|high-affinity zinc II ion transport|zinc II ion transmembrane import The directed movement of zinc(2+) ions from outside of a cell, across the plasma membrane and into the cytosol. CHEBI:21208 L-3'-bromophenylalanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21208 UBERON:0002259 corpora quadrigemina biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002259 set of colliculi|corpora quadrigemina|colliculi|quadrigeminal body Either of the two pairs of colliculi on the dorsal surface of the midbrain composed of white matter externally and gray matter within, the superior pair containing correlation centers for optic reflexes and the inferior pair containing correlation centers for auditory reflexes[BTO]. GO:0071577 zinc ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071577 zinc ion membrane transport|zinc II ion transmembrane transport|zinc transmembrane transport A process in which a zinc II ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. GO:0071576 tetrahydrodictyopterin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071576 DH4 binding|D-threo-tetrahydrobiopterin Interacting selectively and non-covalently with tetrahydrodictyopterin, the pterin 2-amino-6-[(1R,2R)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydropteridin-4(3H)-one. GO:0071575 integral component of external side of plasma membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071575 integral to external leaflet of plasma membrane|integral to external side of plasma membrane The component of the plasma membrane consisting of the gene products that penetrate only the external side of the membrane. UBERON:0002256 dorsal horn of spinal cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002256 cornu dorsale|dorsal grey column of spinal cord|dorsal gray horn|posterior gray column of spinal cord|dorsal region of mature spinal cord|spinal cord posterior horn|dorsal gray matter of spinal cord|posterior grey column of spinal cord|cornu posterius medullae spinalis|spinal cord dorsal horns|dorsal grey horn|columna grisea posterior medullae spinalis|posterior gray horn of spinal cord|dorsal horn of the spinal cord|posterior horn of spinal cord|dorsal horn|dorsal region of spinal cord|dorsal gray column of spinal cord|spinal cord dorsal horn|dorsal horn spinal cord|dorsal spinal cord The pronounced, dorsolaterally oriented ridge of grey matter in each lateral half of the spinal cord[MP]. the dorsal (more towards the back) grey matter of the spinal cord. It receives several types of sensory information from the body, including light touch, proprioception, and vibration. This information is sent from receptors of the skin, bones, and joints through sensory neurons whose cell bodies lie in the dorsal root ganglion[WP]. The dorsal region of the mature spinal cord contains neurons that process and relay sensory input[GO]. GO:0071574 protein localization to medial cortex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071574 protein localisation to medial cortex A process in which a protein is transported to, or maintained in, the medial cortex. GO:0071573 shelterin complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071573 telosome assembly|Pot1-Tpz1 complex assembly|shelterin complex formation|Pot1 complex assembly The aggregation, arrangement and bonding together of a set of components to form a shelterin complex. A shelterin complex is a nuclear telomere cap complex that is formed by the association of telomeric ssDNA- and dsDNA-binding proteins with telomeric DNA, and is involved in telomere protection and recruitment of telomerase. GO:0007119 budding cell isotropic bud growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007119 isotropic bud growth Unlocalized bud growth such that the entire surface of the bud expands evenly, in a cell that reproduces by budding. GO:0007118 budding cell apical bud growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007118 apical bud growth Growth at the tip of a bud, in a cell that reproduces by budding. GO:0007117 budding cell bud growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007117 bud growth The process in which the bud portion of a cell that reproduces by budding irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present. GO:0007116 regulation of cell budding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007116 regulation of budding Any process that modulates the frequency, rate or extent of the formation and growth of cell buds. GO:0007115 obsolete bud site selection/establishment of cell polarity (sensu Saccharomyces) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007115 bud site selection/establishment of cell polarity (sensu Saccharomyces) OBSOLETE. (Was not defined before being made obsolete). GO:0046723 malic acid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046723 malate secretion|hydroxysuccinic acid secretion The controlled release of malic acid, hydroxybutanedioic (hydroxysuccinic) acid, by a cell or a tissue. GO:0007114 cell budding biolink:BiologicalProcess go-plus goslim_yeast|goslim_candida http://purl.obolibrary.org/obo/GO_0007114 budding A form of asexual reproduction, occurring in certain bacteria and fungi (e.g. yeasts) and some primitive animals in which an individual arises from a daughter cell formed by pinching off a part of the parent cell. The budlike outgrowths so formed may sometimes remain attached to the parent cell. GO:0046722 lactic acid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046722 lactate secretion The controlled release of lactic acid, 2-hydroxypropanoic acid, by a cell or a tissue. GO:0007113 endomitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007113 Wikipedia:Mitosis#Endomitosis endomitosis A mitotic cell cycle in which chromosomes are replicated and sister chromatids separate, but spindle formation, nuclear membrane breakdown and nuclear division do not occur, resulting in an increased number of chromosomes in the cell. GO:0046721 formic acid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046721 formate secretion The controlled release of formic acid, HCOOH, by a cell or a tissue. CHEBI:84789 1-palmitoyl-2-[(9Z,12Z,15Z)-octadecatrienoyl]-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84789 GO:0007112 male meiosis cytokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007112 cytokinesis involved in male meiotic cell cycle|cytokinesis after male meiosis A cell cycle process that occurs as part of the male meiotic cell cycle and results in the division of the cytoplasm of a cell to produce two daughter cells. GO:0046720 citric acid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046720 citrate secretion The controlled release of citric acid, 2-hydroxy-1,2,3-propanetricarboxylic acid, by a cell or a tissue. CHEBI:84788 trans,trans-2,4-hexadienoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84788 GO:0007111 meiosis II cytokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007111 cytokinesis after meiosis II A cell cycle process that results in the division of the cytoplasm of a cell after meiosis II, resulting in the separation of the original cell into two daughter cells. GO:0007110 meiosis I cytokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007110 cytokinesis after meiosis I A cell cycle process that results in the division of the cytoplasm of a cell after meiosis I, resulting in the separation of the original cell into two daughter cells. CHEBI:84786 1-palmitoyl-2-[(6Z,9Z,12Z)-octadecatrienoyl]-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84786 GO:0046729 viral procapsid biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0046729 A stable empty viral capsid produced during the assembly of viruses. GO:0046728 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046728 GO:0046727 capsomere biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0046727 Wikipedia:Capsomere capsomer Any of the protein subunits that comprise the closed shell or coat (capsid) of certain viruses. GO:0046726 positive regulation by virus of viral protein levels in host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046726 stimulation of viral protein levels in host cell|positive regulation of viral protein levels|up-regulation of viral protein levels in host cell|upregulation of viral protein levels in host cell|up regulation of viral protein levels in host cell|activation of viral protein levels in host cell Any process where the infecting virus increases the levels of viral proteins in a cell. GO:0046725 negative regulation by virus of viral protein levels in host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046725 negative regulation of viral protein levels|down-regulation of viral protein levels in host cell|inhibition of viral protein levels in host cell|down regulation of viral protein levels in host cell|downregulation of viral protein levels in host cell Any process where the infecting virus reduces the levels of viral proteins in a cell. GO:0046724 oxalic acid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046724 oxalate secretion The controlled release of oxalic acid, ethanedioic acid, by a cell or a tissue. GO:0007129 homologous chromosome pairing at meiosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007129 Wikipedia:Synapsis chromosomal synapsis|homologous chromosome pairing at meiosis|chromosomal pairing|synapsis The meiotic cell cycle process where side by side pairing and physical juxtaposition of homologous chromosomes is created during meiotic prophase. Homologous chromosome pairing begins when the chromosome arms begin to pair from the clustered telomeres and ends when synaptonemal complex or linear element assembly is complete. GO:0007128 meiotic prophase I biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0007128 The cell cycle phase which is the first stage of meiosis I and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell. GO:0007127 meiosis I biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007127 Wikipedia:Meiosis#Meiosis_I meiosis I nuclear division The first meiotic nuclear division in which homologous chromosomes are paired and segregated from each other, producing two haploid daughter nuclei. GO:0007126 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007126 GO:0046734 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046734 GO:0046733 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046733 GO:0007125 obsolete invasive growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007125 invasive growth OBSOLETE. (Was not defined before being made obsolete). GO:0046732 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046732 GO:0007124 pseudohyphal growth biolink:BiologicalProcess go-plus goslim_yeast|goslim_candida http://purl.obolibrary.org/obo/GO_0007124 The process in which cells grow as a chain of physically attached, elongated cells in response to an environmental stimulus or stimuli. GO:0046731 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046731 GO:0007123 obsolete bud scar accumulation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007123 bud scar accumulation OBSOLETE. (Was not defined before being made obsolete). GO:0046730 induction by virus of host immune response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046730 passive induction of host innate immune response by virus|passive viral induction of innate immune response in host|passive induction of host cell-mediated immune response by virus|passive viral activation of humoral immune response in host|passive viral induction of host immune response|passive viral induction of cell-mediated immune response in host|passive induction of host immune response by virus|passive induction of innate immune response in host by virus|passive viral activation of innate immune response in host|passive activation of host immune response by virus|active viral induction of host immune response|passive induction of humoral immune response in host by virus|active induction of host immune response by virus|passive viral induction of humoral immune response in host|passive induction of host humoral immune response by virus|passive viral activation of cell-mediated immune response in host|passive induction of cell-mediated immune response in host by virus|activation of host immune response by virus The induction by a virus of an immune response in the host organism. GO:0007122 obsolete loss of asymmetric budding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007122 loss of asymmetric budding OBSOLETE. (Was not defined before being made obsolete). OBO:GOCHE_38632 substance with membrane transport modulator role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_38632 GO:0007121 bipolar cellular bud site selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007121 polar budding|bipolar budding|bipolar bud site selection The process of defining subsequent sites of bud emergence such that budding takes place at alternating poles of a budding cell. GO:0007120 axial cellular bud site selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007120 axial budding|axial bud site selection The process of defining the next site of bud emergence adjacent to the last site of bud emergence on a budding cell. CHEBI:84793 trans-dec-3-enoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84793 GO:0046739 transport of virus in multicellular host biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046739 viral spread within multicellular host|spread of virus within multicellular host|spread of virus in multicellular host The transport of a virus between cells in a multicellular organism. The cells can be adjacent or spatially separated (e.g. in different tissues or organs). GO:0046738 induction of innate immune response in host by virus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046738 active viral induction of innate immune response in host|active induction of innate immune response in host by virus The intentional, virally-encoded stimulation of an innate host defense response to viral infection. CHEBI:84791 (3E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84791 CHEBI:84790 trans-3-hexenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84790 GO:0046737 induction of cell-mediated immune response in host by virus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046737 active induction of cell-mediated immune response in host by virus|active viral induction of cell-mediated immune response in host The intentional, virally-encoded stimulation of a cell-mediated host defense response to viral infection. GO:0046736 induction of humoral immune response in host by virus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046736 active viral induction of humoral immune response in host|active induction of humoral immune response in host by virus The intentional, virally-encoded stimulation of a host humoral defense response to viral infection. GO:0046735 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046735 GO:0046745 viral capsid secondary envelopment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046745 viral budding from plasma membrane by viral capsid re-envelopment|virus budding from ER membrane by viral capsid re-envelopment|plasma membrane viral budding during viral capsid re-envelopment|virus budding from nuclear membrane during viral capsid re-envelopment|virus budding from plasma membrane during viral capsid re-envelopment|virus budding from Golgi membrane during viral capsid re-envelopment|viral budding from inner nuclear membrane by viral capsid re-envelopment|virus budding from outer nuclear membrane during viral capsid re-envelopment|inner nuclear membrane viral budding during viral capsid re-envelopment|virus budding from inner nuclear membrane during viral capsid re-envelopment|virus budding from Golgi membrane by viral capsid re-envelopment|virus budding from nuclear membrane by viral capsid re-envelopment|viral budding from ER membrane during viral capsid re-envelopment|virus budding from outer nuclear membrane by viral capsid re-envelopment|viral budding from nuclear membrane during viral capsid re-envelopment|viral budding from ER membrane by viral capsid re-envelopment|viral budding from Golgi membrane during viral capsid re-envelopment|viral budding from outer nuclear membrane during viral capsid re-envelopment|endoplasmic reticulum membrane viral budding during viral capsid re-envelopment|virus budding from inner nuclear membrane by viral capsid re-envelopment|virus budding from ER membrane during viral capsid re-envelopment|ER membrane viral budding during viral capsid re-envelopment|viral budding from Golgi membrane by viral capsid re-envelopment|viral budding from nuclear membrane by viral capsid re-envelopment|viral budding from plasma membrane during viral capsid re-envelopment|viral capsid re-envelopment|outer nuclear membrane viral budding during viral capsid re-envelopment|nuclear membrane viral budding during viral capsid re-envelopment|viral budding from outer nuclear membrane by viral capsid re-envelopment|Golgi membrane viral budding during viral capsid re-envelopment|viral budding from inner nuclear membrane during viral capsid re-envelopment The process in which a capsid acquires another membrane envelope, subsequent to acquiring an initial membrane envelope. GO:0046744 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046744 GO:0046743 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046743 GO:0046742 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046742 GO:0046741 transport of virus in host, tissue to tissue biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046741 tissue to tissue spread of virus within host|viral spread within host, tissue to tissue|spread of virus within host, tissue to tissue|spread of virus in host, tissue to tissue The transport of a virus between tissues in a multicellular organism. GO:0046740 transport of virus in host, cell to cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046740 VZ:1018 spread of virus in host, cell to cell|intercellular virus transport|cell to cell spread of virus within host|viral spread within host, cell to cell|spread of virus within host, cell to cell The transport of a virus between adjacent cells in a multicellular organism. GO:0071709 membrane assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071709 The aggregation, arrangement and bonding together of a set of components to form a membrane. GO:0071708 immunoglobulin light chain V-J recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071708 immunoglobulin V-J joining|immunoglobulin V(D)J recombination|immunoglobulin V(D)J joining The process in which immunoglobulin light chain V and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). GO:0071707 immunoglobulin heavy chain V-D-J recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071707 immunoglobulin V(D)J recombination|immunoglobulin V-D-J joining|immunoglobulin V(D)J joining The process in which immunoglobulin heavy chain V, D, and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). GO:0071706 tumor necrosis factor superfamily cytokine production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0071706 TNFSF cytokine production|TNF superfamily production The appearance of any member of the TNF superfamily due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0071705 nitrogen compound transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071705 The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0046749 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046749 GO:0071704 organic substance metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071704 organic molecular entity metabolism|organic substance metabolism|organic molecular entity metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon. GO:0046748 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046748 GO:0071703 detection of organic substance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071703 The series of events in which an organic substance stimulus is received by a cell and converted into a molecular signal. GO:0046747 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046747 GO:0071702 organic substance transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071702 The directed movement of organic substances into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. An organic substance is a molecular entity that contains carbon. GO:0046746 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046746 GO:0071701 regulation of MAPK export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071701 regulation of MAPK export out of nucleus|regulation of cytoplasmic translocation of MAP kinase|regulation of cytoplasmic translocation of mitogen-activated protein kinase|regulation of MAPK export from cell nucleus|regulation of MAPK transport from nucleus to cytoplasm|regulation of MAPK-nucleus export Any process that modulates the frequency, rate or extent of the directed movement of a MAP kinase from the nucleus to the cytoplasm. GO:0071700 olfactory placode maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071700 A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory placode to attain its fully functional state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity. GO:0007109 obsolete cytokinesis, completion of separation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007109 cytokinesis, completion of separation|completion of separation involved in cytokinesis OBSOLETE. The process of finishing cell separation, which results in two physically separated cells. GO:0007108 obsolete cytokinesis, initiation of separation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007108 cytokinesis, initiation of separation|initiation of separation involved in cytokinesis OBSOLETE. The process involved in starting cell separation. GO:0007107 membrane addition at site of cytokinesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007107 cytokinesis, membrane recruitment/generation Any process involved in the net addition of membrane at the site of cytokinesis; includes vesicle recruitment and fusion, local lipid synthesis and insertion. GO:0007106 obsolete cytokinesis, protein recruitment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007106 cytokinesis, protein recruitment OBSOLETE. (Was not defined before being made obsolete). GO:0007105 cytokinesis, site selection biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007105 site selection involved in cytokinesis|site selection involved in cell cycle cytokinesis The process of marking the place where cytokinesis will occur. GO:0007104 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007104 GO:0046756 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046756 GO:0046755 viral budding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046755 VZ:1947 virus budding|viral capsid envelopment|virion budding A viral process by which enveloped viruses acquire a host-derived membrane enriched in viral proteins to form their external envelope. The process starts when nucleocapsids, assembled or in the process of being built, induce formation of a membrane curvature in the host plasma or organelle membrane and wrap up in the forming bud. The process ends when the bud is eventually pinched off by membrane scission to release the enveloped particle into the lumenal or extracellular space. GO:0007103 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007103 GO:0046754 viral exocytosis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046754 The exit of enveloped or unenveloped virion particles from the host cell by exocytosis, without causing cell lysis. GO:0007102 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007102 GO:0046753 non-lytic viral release biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046753 The exit of a viral particle from a cell that does not involve cell lysis. GO:0007101 obsolete male meiosis centrosome cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007101 centrosome cycle involved in male meiotic cell cycle OBSOLETE. Centrosome duplication and separation in the context of a meiotic cell cycle in a male organism. GO:0046752 viral capsid precursor transport to host cell nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046752 establishment and maintenance of viral capsid precursor localization in nucleus|localization of viral capsid precursors in nucleus|nuclear localization of viral capsid precursors|viral capsid precursor localization in host cell nucleus|viral capsid precursor localisation in host cell nucleus|viral capsid precursor localization to host cell nucleus Any process in which viral capsid precursors are transported to a specific location in the nucleus, thus accumulating the necessary components for assembly of a capsid. GO:0007100 mitotic centrosome separation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007100 Separation of duplicated centrosome components at the beginning of mitosis. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle. GO:0046751 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046751 GO:0046750 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046750 CHEBI:59793 monothioacetal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59793 CHEBI:59792 thioacetal biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59792 CHEBI:59791 gibberellin A3 O-beta-D-glucoside(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59791 GO:0046759 obsolete lytic virus budding from plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046759 lytic plasma membrane viral budding|lytic viral budding from plasma membrane|lytic virus budding from plasma membrane OBSOLETE. A form of viral release in which the nucleocapsid evaginates from the host nuclear membrane system, resulting in envelopment of the virus and cell lysis. GO:0046758 obsolete lytic virus budding from Golgi membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046758 lytic Golgi membrane viral budding|lytic viral budding from Golgi membrane|lytic virus budding from Golgi membrane OBSOLETE. A form of viral release in which the nucleocapsid evaginates from the host Golgi membrane system, resulting in envelopment of the virus and cell lysis. GO:0046757 obsolete lytic virus budding from ER membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046757 lytic virus budding from ER membrane|lytic ER membrane viral budding|lytic endoplasmic reticulum membrane viral budding|lytic viral budding from ER membrane OBSOLETE. A form of viral release in which the nucleocapsid evaginates from the host endoplasmic reticulum membrane system, resulting in envelopment of the virus and cell lysis. UBERON:0002316 white matter biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002316 white matter of neuraxis|white mater|CNS tracts and commissures|CNS white matter|substantia alba|CNS tract/commissure|neuronal white matter|white substance Neural tissue consisting of myelinated axons connecting grey matter areas of the central nervous system. UBERON:0002319 mesangium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002319 The inner layer of the glomerulus, within the basement membrane surrounding the glomerular capillaries. UBERON:0002318 white matter of spinal cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002318 substantia alba medullae spinalis|white matter of neuraxis of spinal cord|white substance of spinal cord|spinal cord white substance|spinal cord white matter|spinal cord white matter of neuraxis The regions of the spinal cord that are largely or entirely composed of myelinated nerve cell axons and contain few or no neural cell bodies or dendrites. CL:2000078 placental pericyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000078 Any pericyte cell that is part of a placenta. GO:0046767 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046767 GO:0046766 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046766 GO:0046765 viral budding from nuclear membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046765 virus budding from nuclear membrane during viral capsid envelopment|virus budding from nuclear membrane|nuclear membrane viral budding|nuclear membrane viral budding during viral capsid envelopment|viral budding from nuclear membrane by viral capsid envelopment|virus budding from nuclear membrane by viral capsid envelopment|viral budding from nuclear membrane during viral capsid envelopment A viral budding that starts with formation of a membrane curvature in the host nuclear membrane. GO:0046764 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046764 CL:2000074 splenocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000074 Any leukocyte that is part of a spleen. GO:0046763 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046763 GO:0046762 viral budding from endoplasmic reticulum membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046762 viral budding from ER membrane|viral budding from ER membrane during viral capsid envelopment|virus budding from ER membrane by viral capsid envelopment|virus budding from ER membrane during viral capsid envelopment|virus budding from ER membrane|viral budding from ER membrane by viral capsid envelopment|ER membrane viral budding|ER membrane viral budding during viral capsid envelopment|endoplasmic reticulum membrane viral budding|endoplasmic reticulum membrane viral budding during viral capsid envelopment A viral budding that starts with formation of a membrane curvature in the host ER membrane. GO:0046761 viral budding from plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046761 virus budding from plasma membrane during viral capsid envelopment|virus budding from plasma membrane|viral budding from plasma membrane by viral capsid envelopment|plasma membrane viral budding|plasma membrane viral budding during viral capsid envelopment|viral budding from plasma membrane during viral capsid envelopment|virus budding from plasma membrane by viral capsid envelopment A viral budding that starts with formation of a membrane curvature in the host plasma membrane. GO:0046760 viral budding from Golgi membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046760 virus budding from Golgi membrane during viral capsid envelopment|virus budding from Golgi membrane|Golgi membrane viral budding|viral budding from Golgi membrane by viral capsid envelopment|Golgi membrane viral budding during viral capsid envelopment|viral budding from Golgi membrane during viral capsid envelopment|virus budding from Golgi membrane by viral capsid envelopment A viral budding that starts with formation of a membrane curvature in the host Golgi membrane. CL:2000075 anterior visceral endoderm cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000075 Any endodermal cell that is part of a anterior visceral endoderm. CHEBI:59783 2-hydroxy-4-methylvaleric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59783 GO:0071729 beak morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071729 The process in which the anatomical structures of the beak are generated and organized. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus. GO:0071728 beak development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071728 The progression of the beak over time from its initial formation until its mature state. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus. GO:0071727 cellular response to triacyl bacterial lipopeptide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071727 cellular response to triacylated bacterial lipoprotein Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triacylated bacterial lipopeptide stimulus. CHEBI:59780 cyclic hemiketal biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59780 GO:0071726 cellular response to diacyl bacterial lipopeptide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071726 cellular response to diacylated bacterial lipoprotein Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diacylated bacterial lipopeptide stimulus. GO:0071725 response to triacyl bacterial lipopeptide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071725 response to triacylated bacterial lipoprotein Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triacylated bacterial lipopeptide stimulus. GO:0046769 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046769 GO:0071724 response to diacyl bacterial lipopeptide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071724 response to diacylated bacterial lipoprotein Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diacylated bacterial lipopeptide stimulus. GO:0046768 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046768 UBERON:0002324 muscle of back biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002324 back muscle organ|muscle organ of back|back muscle Any muscle organ that is part of a back [Automatically generated definition]. GO:0071723 lipopeptide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071723 bacterial lipoprotein binding|bacterial lipopeptide binding Interacting selectively and non-covalently with a lipopeptide, any of a group of organic compounds comprising two or more amino acids linked by peptide bonds and containing a nonprotein group consisting of a lipid or lipids. UBERON:0002323 coelemic cavity lumen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002323 space of body compartment|celom|ventral body cavity|coelomic cavity lumen|coelome|main body cavity|hemocoel|coelom|coelomic cavity|body cavity The cavity within the body of all animals higher than the coelenterates and certain primitive worms, formed by the splitting of the embryonic mesoderm into two layers. In mammals it forms the peritoneal, pleural, and pericardial cavities. GO:0071722 detoxification of arsenic-containing substance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071722 detoxification of arsenic Any process that reduces or removes the toxicity of compounds containing arsenic, including arsenates, arsenites, and arsenides. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of arsenic or arsenic-containing compounds. UBERON:0002326 lamina propria of urethra biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002326 urethral lamina propria|urethra lamina propria mucosae|urethra lamina propria mucosa|urethra lamina propria|lamina propria mucosae of urethra|lamina propria mucosa of urethra A lamina propria that is part of a urethra [Automatically generated definition]. GO:0071721 sodium-independent thromboxane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071721 The directed, sodium-independent, movement of thromboxanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A thromboxane is any of a class of oxygenated oxane derivatives, originally derived from prostaglandin precursors in platelets, that stimulate aggregation of platelets and constriction of blood vessels. UBERON:0002325 epithelium of urethra biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002325 urethral epithelium|urethra epithelium|epithelial tissue of urethra|urethral seam|urethra epithelial tissue|urethral plate The urethra is a renal system organ that carries urine from the bladder to outside the body. The epithelium is the tubular, planar layer of cells through which the urine passes.. CHEBI:59789 S-adenosyl-L-methionine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59789 GO:0071720 sodium-independent prostaglandin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071720 The directed, sodium-independent, movement of prostaglandins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UBERON:0002320 glomerular mesangium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002320 A thin membrane which helps to support the capillary loops in a renal glomerulus. It is connective tissue composed of mesangial cells - myofibroblasts phenotypically related to vascular smooth muscle cells (muscle, smooth, vascular), phagocytes and the mesangial extracellular matrix. CHEBI:59786 thioaldehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59786 GO:0046770 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046770 GO:1900606 tensidol B metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900606 tensidol B metabolism The chemical reactions and pathways involving tensidol B. GO:1900605 tensidol A biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900605 tensidol A synthesis|tensidol A formation|tensidol A biosynthesis|tensidol A anabolism The chemical reactions and pathways resulting in the formation of tensidol A. GO:1900608 tensidol B biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900608 tensidol B synthesis|tensidol B formation|tensidol B biosynthesis|tensidol B anabolism The chemical reactions and pathways resulting in the formation of tensidol B. CL:2000061 placental amniotic mesenchymal stromal cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000061 Any mesenchymal stem cell that is part of a placenta. GO:1900607 tensidol B catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900607 tensidol B catabolism|tensidol B degradation|tensidol B breakdown The chemical reactions and pathways resulting in the breakdown of tensidol B. CHEBI:21188 L-2'-bromophenylalanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21188 CL:2000060 placental villous trophoblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000060 vCTB|villous cytotrophoblast A trophoblast of placental villi. These cells fuse to form synctial trophoplast - the placental side of the interface between the placenta and maternal blood sinusoids in the decidua. GO:1900602 endocrocin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900602 endocrocin anabolism|endocrocin biosynthesis|endocrocin synthesis|endocrocin formation The chemical reactions and pathways resulting in the formation of endocrocin. GO:1900601 endocrocin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900601 endocrocin degradation|endocrocin breakdown|endocrocin catabolism The chemical reactions and pathways resulting in the breakdown of endocrocin. UBERON:0002305 layer of hippocampus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002305 hippocampus layer|layer of cornu ammonis|cytoarchitectural fields of hippocampal formation|hippocampus proper layer The layers of the laminar structure of the hippocampus. GO:1900604 tensidol A catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900604 tensidol A catabolism|tensidol A degradation|tensidol A breakdown The chemical reactions and pathways resulting in the breakdown of tensidol A. UBERON:0002308 nucleus of brain biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002308 brain nucleus|brain nuclei A neural nucleus that is part of the brain. UBERON:0002307 choroid plexus of lateral ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002307 lateral ventricle choroid plexus|lateral ventricle chorioid plexus of cerebral hemisphere|choroid plexus telencephalic ventricle|chorioid plexus of lateral ventricle|chorioid plexus of cerebral hemisphere of lateral ventricle Part of choroid plexus contained in the lateral ventricle GO:1900603 tensidol A metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900603 tensidol A metabolism The chemical reactions and pathways involving tensidol A. GO:0046778 modification by virus of host mRNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046778 viral perturbation of host mRNA processing Any viral process that interferes with the processing of mRNA in the host cell. CL:2000067 cardiac atrium fibroblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000067 Any fibroblast that is part of a cardiac atrium. CL:2000066 cardiac ventricle fibroblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000066 Any fibroblast that is part of a cardiac ventricle. GO:0046777 protein autophosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046777 Wikipedia:Autophosphorylation protein amino acid autophosphorylation The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation). GO:1900600 endocrocin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900600 endocrocin metabolism The chemical reactions and pathways involving endocrocin. CL:2000069 gallbladder fibroblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000069 Any fibroblast that is part of a gallbladder. GO:0046776 suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046776 VZ:819 inhibition of host MHC class I molecule presentation by virus|suppression by virus of host MHC class I cell surface presentation|major histocompatibility complex|suppression by virus of MHC class I cell surface presentation in host|negative regulation by virus of MHC class I cell surface presentation Any viral process that inhibits a host antigen-presenting cell expressing a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules. GO:0046775 suppression by virus of host cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046775 negative regulation by virus of host cytokine production Any viral process that results in the inhibition of host cell cytokine production. CL:2000068 pericardium fibroblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000068 Any fibroblast that is part of a pericardium. GO:0046774 suppression by virus of host intracellular interferon activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046774 suppression by virus of intracellular interferon activity in host|negative regulation by virus of intracellular interferon activity Any viral process that results in the inhibition of interferon activity within the host cell. CL:2000063 ovarian fibroblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000063 Any fibroblast that is part of a female gonad. GO:0046773 suppression by virus of host translation termination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046773 suppression by virus of host termination of protein biosynthetic process|viral inhibition of termination of host cell protein biosynthetic process|viral inhibition of termination of host cell protein biosynthesis|negative regulation by virus of host cell protein biosynthesis shutoff|negative regulation by virus of host cell protein biosynthetic process shutoff|viral inhibition of host cell protein biosynthetic process shutoff|viral inhibition of host cell protein biosynthesis shutoff|viral suppression of termination by host of host cell protein biosynthesis|viral suppression of termination by host of host cell protein biosynthetic process Any viral process that stops, prevents, or reduces the frequency, rate or extent of translational termination of a host mRNA. GO:0046772 viral budding from outer nuclear membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046772 virus budding from outer nuclear membrane by viral capsid envelopment|viral budding from outer nuclear membrane during viral capsid envelopment|virus budding from outer nuclear membrane during viral capsid envelopment|outer nuclear membrane viral budding during viral capsid envelopment The envelopment of a virus, in which the nucleocapsid evaginates from the host outer nuclear membrane system, thus acquiring a membrane envelope. GO:0046771 viral budding from inner nuclear membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046771 viral budding from inner nuclear membrane during viral capsid envelopment|virus budding from inner nuclear membrane during viral capsid envelopment|viral budding from inner nuclear membrane by viral capsid envelopment|inner nuclear membrane viral budding during viral capsid envelopment|virus budding from inner nuclear membrane by viral capsid envelopment The envelopment of a virus, in which the nucleocapsid evaginates from the host inner nuclear membrane system into the perinuclear space, thus acquiring a membrane envelope. CHEBI:45133 pivalic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_45133 CL:2000064 ovarian surface epithelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000064 Any epithelial cell that is part of a female gonad. CHEBI:59772 hemiketal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59772 GO:0071719 sodium-independent leukotriene transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071719 The directed, sodium-independent, movement of leukotrienes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Leukotrienes are linear C20 endogenous metabolites of arachidonic acid (icosa-5,8,11,14-tetraenoic acid) containing a terminal carboxy function and four or more double bonds (three or more of which are conjugated) as well as other functional groups. GO:0071718 sodium-independent icosanoid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071718 sodium-independent eicosanoid transport The directed, sodium-independent, movement of icosanoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Icosanoids are unsaturated C20 fatty acids and skeletally related compounds. GO:0071717 thromboxane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071717 The directed movement of thromboxanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A thromboxane is any of a class of oxygenated oxane derivatives, originally derived from prostaglandin precursors in platelets, that stimulate aggregation of platelets and constriction of blood vessels. CHEBI:59770 cyclic acetal biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59770 GO:0071716 leukotriene transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071716 The directed movement of leukotrienes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Leukotrienes are linear C20 endogenous metabolites of arachidonic acid (icosa-5,8,11,14-tetraenoic acid) containing a terminal carboxy function and four or more double bonds (three or more of which are conjugated) as well as other functional groups. GO:0071715 icosanoid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071715 eicosanoid transport The directed movement of icosanoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Icosanoids are unsaturated C20 fatty acids and skeletally related compounds. GO:0071714 icosanoid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071714 eicosanoid transmembrane transporter activity Enables the transfer of icosanoids from one side of a membrane to the other. GO:0046779 obsolete suppression by virus of expression of host genes with introns biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046779 negative regulation by virus of expression of host genes with introns|viral inhibition of expression of host genes with introns OBSOLETE. Any viral process that discriminates against and subsequently inhibits host transcripts containing introns, thus allowing only intronless viral mRNA to be fully processed. GO:0071713 para-aminobenzoyl-glutamate hydrolase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071713 Catalysis of the reaction: para-aminobenzoyl-glutamate + H2O = para-aminobenzoate + L-glutamate. GO:0071712 ER-associated misfolded protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071712 endoplasmic reticulum-associated misfolded protein catabolism|proteasomal protein catabolism of misfolded ER proteins|ER-associated misfolded protein catabolism|ER-associated misfolded protein degradation|ER-associated misfolded protein breakdown|endoplasmic reticulum-associated misfolded protein catabolic process The chemical reactions and pathways resulting in the breakdown of misfolded proteins transported from the endoplasmic reticulum and targeted to cytoplasmic proteasomes for degradation. GO:0071711 basement membrane organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071711 basement membrane organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane. GO:0071710 membrane macromolecule biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071710 membrane macromolecule formation|membrane macromolecule biosynthesis|membrane macromolecule anabolism|membrane macromolecule synthesis The chemical reactions and pathways resulting in the formation of a macromolecule destined to form part of a membrane in a cell. UBERON:0002315 gray matter of spinal cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002315 gray substance of spinal cord|spinal cord grey matter|spinal cord gray matter|gray matter of spinal cord|grey matter of spinal cord|spinal cord grey substance|substantia grisea medullae spinalis|grey substance of spinal cord The ridge-shaped grey matter of the spinal cord that extends longitudunally through the center of each half of the spinal cord, and are largely or entirely composed of nerve cell bodies and their dendrites and some supportive tissue. CHEBI:59779 cyclic ketal biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59779 UBERON:0002314 midbrain tectum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002314 mesencephalic tectum|tectum mesencephalicum|tectum of midbrain|tectum mesencephali|neuraxis tectum|t. mesencephali|tectum Dorsal part of the midbrain, consisting of the superior and inferior colliculi and the pretectal nuclei (MM). CHEBI:59777 ketal biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59777 GO:1900609 F-9775A metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900609 F-9775A metabolism The chemical reactions and pathways involving F-9775A. CHEBI:59776 D-glyceraldehyde 3-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59776 GO:1900617 emericellamide A biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900617 emericellamide A biosynthesis|emericellamide A anabolism|emericellamide A synthesis|emericellamide A formation The chemical reactions and pathways resulting in the formation of emericellamide A. GO:0046781 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046781 CL:2000092 hair follicular keratinocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000092 Any keratinocyte that is part of a hair follicle. GO:0046780 suppression by virus of host mRNA splicing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046780 viral dispersion of host splicing factors|negative regulation by virus of host mRNA splicing|viral inhibition of host mRNA splicing|suppression by virus of host splicing factor activity Any viral process that inhibits the splicing of host mRNA, thus reducing host protein production. GO:1900616 emericellamide A catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900616 emericellamide A degradation|emericellamide A breakdown|emericellamide A catabolism The chemical reactions and pathways resulting in the breakdown of emericellamide A. GO:1900619 acetate ester metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900619 acetate ester metabolism|acetyl ester metabolism|acetyl ester metabolic process The chemical reactions and pathways involving an acetate ester, any carboxylic ester where the carboxylic acid component is acetic acid. GO:1900618 regulation of shoot system morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900618 regulation of shoot morphogenesis Any process that modulates the frequency, rate or extent of shoot morphogenesis. CL:2000093 bronchus fibroblast of lung biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000093 Any fibroblast of lung that is part of a bronchus. GO:1900613 F-9775B catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900613 F-9775B catabolism|F-9775B degradation|F-9775B breakdown The chemical reactions and pathways resulting in the breakdown of F-9775B. GO:1900612 F-9775B metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900612 F-9775B metabolism The chemical reactions and pathways involving F-9775B. GO:1900615 emericellamide A metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900615 emericellamide A metabolism The chemical reactions and pathways involving emericellamide A. CL:2000090 dentate gyrus of hippocampal formation stellate cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000090 Any stellate cell that is part of a dentate gyrus of hippocampal formation. GO:1900614 F-9775B biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900614 F-9775B synthesis|F-9775B formation|F-9775B biosynthesis|F-9775B anabolism The chemical reactions and pathways resulting in the formation of F-9775B. CHEBI:45129 methylphosphonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_45129 GO:0046789 host cell surface receptor binding biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0046789 cell surface antigen activity, host-interacting|cell surface receptor ligand Interacting selectively and non-covalently with a receptor on the host cell surface. GO:0046788 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046788 GO:1900611 F-9775A biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900611 F-9775A synthesis|F-9775A formation|F-9775A biosynthesis|F-9775A anabolism The chemical reactions and pathways resulting in the formation of F-9775A. GO:0046787 viral DNA repair biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046787 The process of restoring viral DNA after damage or errors in replication. GO:1900610 F-9775A catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900610 F-9775A catabolism|F-9775A degradation|F-9775A breakdown The chemical reactions and pathways resulting in the breakdown of F-9775A. GO:0046786 viral replication complex formation and maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046786 The process of organizing and assembling viral replication proteins in preparation for viral replication. CHEBI:45126 7-aminomethyl-7-deazaguanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_45126 GO:0046785 microtubule polymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046785 microtubule assembly|microtubule formation The addition of tubulin heterodimers to one or both ends of a microtubule. GO:0046784 viral mRNA export from host cell nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046784 intronless viral mRNA export from host nucleus|intronless viral mRNA transport from nucleus to cytoplasm|intronless viral mRNA-nucleus export|intronless viral mRNA export out of nucleus|intronless viral mRNA export from host cell nucleus The directed movement of intronless viral mRNA from the host nucleus to the cytoplasm for translation. GO:0046783 modification by virus of host polysomes biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046783 viral perturbation of polysomes Any viral process that interferes with and inhibits the assembly and function of polysomes. GO:0046782 regulation of viral transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046782 Any process that modulates the frequency, rate or extent of the transcription of the viral genome. CL:2000097 midbrain dopaminergic neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000097 Any dopaminergic neuron that is part of a midbrain. CHEBI:35795 polyprenylbenzoquinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35795 NCBITaxon:142796 Eumycetozoa organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_142796 Mycetozoa|Eumycetozoa Zopf, 1884|mycetozoans CHEBI:35794 tetrapyrrole fundamental parent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35794 GO:0071749 polymeric IgA immunoglobulin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071749 pIgA antibody|pIgA1 antibody|polymeric IgA1 antibody|polymeric IgA antibody A protein complex composed of two, three, or four monomeric IgA immunoglobulin complexes linked through both direct disulfide bonds and through disulfide binded monomers of J chain acting as a bridge. Each IgA monomer consists of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds. Dimeric IgA is sometimes complexed additionally with secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. GO:0071748 monomeric IgA immunoglobulin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071748 monomeric IgA antibody|monomeric IgA1 antibody|monomeric IgA2 antibody A protein complex composed of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. GO:0071747 IgA B cell receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071747 membrane-bound IgA2|membrane-bound IgA1|membrane-bound IgA|surface IgA2|surface IgA1|surface IgA An IgA immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins. GO:0071746 IgA immunoglobulin complex, circulating biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071746 IgA antibody|IgA1 antibody|IgA2 antibody A protein complex composed of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, sometimes complexed with J chain or J chain and secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. UBERON:0002302 myocardium of atrium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002302 atrial myocardium|atrium cardiac muscle|atrium myocardium the atrial part of middle layer of the heart, comprised of involuntary muscle GO:0071745 IgA immunoglobulin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071745 IgA1 antibody|IgA2 antibody A protein complex composed of two identical immunoglobulin heavy chains of the IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and sometimes complexed with J chain or J chain and secretory component. An IgA immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. UBERON:0002301 layer of neocortex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002301 lamina of neocortex|layer of neocortex|cerebral cortex layer|cortical layer|neocortex layer One of the layers of the neocortex. GO:0071744 IgE B cell receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071744 membrane-bound IgE|surface IgE An IgE immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins. CHEBI:59769 acetal biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59769 CHEBI:59768 aliphatic aldehyde biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59768 UBERON:0002304 layer of dentate gyrus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002304 dentate gyrus layer|dentate gyrus cell layer One of the three layers of the dentate gyrus of the hippocampal formation. GO:0071743 IgE immunoglobulin complex, circulating biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071743 IgE antibody A protein complex composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. UBERON:0002303 juxtaglomerular apparatus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002303 juxtaglomerular complex|complexus juxtaglomerularis An anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate[GO]. a microscopic structure in the kidney, which regulates the function of each nephron. The juxtaglomerular apparatus is named for its proximity to the glomerulus: it is found between the vascular pole of the renal corpuscle and the returning distal convoluted tubule of the same nephron. This location is critical to its function in regulating renal blood flow and glomerular filtration rate. The three cellular components of the apparatus are the macula densa, extraglomerular mesangial cells, and juxtaglomerular cells (also known as granular cells)[WP]. GO:0071742 IgE immunoglobulin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071742 A protein complex composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgE immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. GO:0071741 IgD immunoglobulin complex, GPI-anchored biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071741 GPI-anchored IgD A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and bound via a GPI-anchor to the plasma membrane of B cells. GO:0071740 IgD B cell receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071740 membrane-bound IgD|surface IgD An IgD immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins. CHEBI:35790 oxazole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35790 CHEBI:59765 boric acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59765 GO:1900628 positive regulation of arugosin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900628 activation of arugosin anabolism|up-regulation of arugosin formation|activation of arugosin biosynthesis|activation of arugosin synthesis|positive regulation of arugosin anabolism|up regulation of arugosin anabolism|activation of arugosin formation|up-regulation of arugosin biosynthetic process|up-regulation of arugosin biosynthesis|positive regulation of arugosin synthesis|up regulation of arugosin synthesis|positive regulation of arugosin formation|up regulation of arugosin formation|upregulation of arugosin biosynthetic process|upregulation of arugosin anabolism|upregulation of arugosin biosynthesis|upregulation of arugosin synthesis|upregulation of arugosin formation|up-regulation of arugosin anabolism|up regulation of arugosin biosynthetic process|up regulation of arugosin biosynthesis|positive regulation of arugosin biosynthesis|activation of arugosin biosynthetic process|up-regulation of arugosin synthesis Any process that activates or increases the frequency, rate or extent of arugosin biosynthetic process. GO:0046792 suppression by virus of host cell cycle arrest biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046792 viral inhibition of cell cycle arrest|negative regulation by virus of cell cycle arrest Viral interference in host cell processes that lead cell cycle arrest, allowing cell division to occur. CHEBI:21165 GDP-alpha-D-mannosylchitobiosyldiphosphodolichol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21165 GO:1900627 negative regulation of arugosin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900627 down-regulation of arugosin biosynthetic process|negative regulation of arugosin biosynthesis|down-regulation of arugosin anabolism|negative regulation of arugosin anabolism|down-regulation of arugosin biosynthesis|down-regulation of arugosin synthesis|negative regulation of arugosin synthesis|inhibition of arugosin biosynthetic process|down-regulation of arugosin formation|negative regulation of arugosin formation|downregulation of arugosin anabolism|inhibition of arugosin biosynthesis|down regulation of arugosin anabolism|downregulation of arugosin synthesis|downregulation of arugosin formation|down regulation of arugosin synthesis|down regulation of arugosin biosynthetic process|down regulation of arugosin biosynthesis|inhibition of arugosin anabolism|down regulation of arugosin formation|downregulation of arugosin biosynthetic process|downregulation of arugosin biosynthesis|inhibition of arugosin synthesis|inhibition of arugosin formation Any process that stops, prevents or reduces the frequency, rate or extent of arugosin biosynthetic process. GO:0046791 obsolete suppression by virus of host complement neutralization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046791 suppression by virus of host complement neutralization|negative regulation by virus of host complement neutralization OBSOLETE. Any viral process that results in the inhibition of complement neutralization of the host cell. GO:0046790 virion binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046790 Interacting selectively and non-covalently with a virion, either by binding to components of the capsid or the viral envelope. CHEBI:21167 GDP-hexose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21167 GO:1900629 methanophenazine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900629 methanophenazine metabolism The chemical reactions and pathways involving methanophenazine. GO:1900624 negative regulation of monocyte aggregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900624 downregulation of monocyte aggregation|negative regulation of mononuclear phagocyte aggregation|down-regulation of mononuclear phagocyte aggregation|down regulation of monocyte aggregation|inhibition of monocyte aggregation|inhibition of mononuclear phagocyte aggregation|down regulation of mononuclear phagocyte aggregation|down-regulation of monocyte aggregation|downregulation of mononuclear phagocyte aggregation Any process that stops, prevents or reduces the frequency, rate or extent of monocyte aggregation. CHEBI:21169 GDP-sugar biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21169 GO:1900623 regulation of monocyte aggregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900623 regulation of mononuclear phagocyte aggregation Any process that modulates the frequency, rate or extent of monocyte aggregation. CHEBI:21168 GDP-mannose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21168 GO:1900626 regulation of arugosin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900626 regulation of arugosin anabolism|regulation of arugosin synthesis|regulation of arugosin formation|regulation of arugosin biosynthesis Any process that modulates the frequency, rate or extent of arugosin biosynthetic process. GO:1900625 positive regulation of monocyte aggregation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900625 activation of mononuclear phagocyte aggregation|upregulation of monocyte aggregation|up-regulation of mononuclear phagocyte aggregation|up-regulation of monocyte aggregation|activation of monocyte aggregation|upregulation of mononuclear phagocyte aggregation|up regulation of mononuclear phagocyte aggregation|up regulation of monocyte aggregation|positive regulation of mononuclear phagocyte aggregation Any process that activates or increases the frequency, rate or extent of monocyte aggregation. GO:1900620 acetate ester biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900620 acetate ester biosynthesis|acetyl ester biosynthesis|acetyl ester biosynthetic process|acetate ester anabolism|acetate ester synthesis|acetate ester formation The chemical reactions and pathways resulting in the formation of an acetate esteran acetate ester, any carboxylic ester where the carboxylic acid component is acetic acid. CL:2000089 dentate gyrus of hippocampal formation granule cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000089 The principal cell type of the dentate gyrus. GO:0046799 recruitment of helicase-primase complex to DNA lesions biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046799 The recruitment of the helicase-primase complex to viral DNA lesions during viral DNA repair. GO:1900622 positive regulation of transcription from RNA polymerase II promoter by calcium-mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900622 upregulation of transcription from RNA polymerase II promoter by calcium-mediated signaling|calcineurin-dependent transcription activation|calcineurin-mediated activation of transcription|upregulation of global transcription from RNA polymerase II promoter by calcium-mediated signaling|positive regulation of gene-specific transcription from RNA polymerase II promoter by calcium-mediated signaling|stimulation of global transcription from RNA polymerase II promoter by calcium-mediated signaling|up regulation of transcription from RNA polymerase II promoter by calcium-mediated signaling|calcineurin-dependent transcriptional induction|up-regulation of global transcription from RNA polymerase II promoter by calcium-mediated signaling|activation of transcription from RNA polymerase II promoter by calcium-mediated signaling|stimulation of transcription from RNA polymerase II promoter by calcium-mediated signaling|activation of global transcription from RNA polymerase II promoter by calcium-mediated signaling|up-regulation of transcription from RNA polymerase II promoter by calcium-mediated signaling|positive regulation of global transcription from Pol II promoter by calcium-mediated signaling|positive regulation of transcription from RNA polymerase II promoter, global by calcium-mediated signaling|positive regulation of transcription from Pol II promoter by calcium-mediated signaling|up regulation of global transcription from RNA polymerase II promoter by calcium-mediated signaling Calcium-mediated signaling that results in positive regulation of transcription from an RNA polymerase II promoter. GO:0046798 viral portal complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0046798 A multimeric ring of proteins through which the DNA enters and exits the viral capsid. GO:1900621 obsolete regulation of transcription from RNA polymerase II promoter by calcium-mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900621 regulation of gene-specific transcription from RNA polymerase II promoter by calcium-mediated signaling|regulation of transcription from Pol II promoter by calcium-mediated signaling|regulation of global transcription from Pol II promoter by calcium-mediated signaling|regulation of transcription from RNA polymerase II promoter, global by calcium-mediated signaling OBSOLETE. Calcium-mediated signaling that results in regulation of transcription from an RNA polymerase II promoter. GO:0046797 viral procapsid maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046797 UniProtKB-KW:KW-1273 capsid maturation|virion maturation|viral capsid maturation The refolding and structural rearrangements of individual capsid subunits to transition from the intermediate procapsid, to the more stable capsid structure. CL:2000085 mononuclear cell of umbilical cord biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000085 Any mononuclear cell that is part of a umbilical cord. GO:0046796 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046796 CHEBI:21161 GDP-D-mannuronic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21161 GO:0046795 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046795 GO:0046794 transport of virus biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0046794 virion transport|viral transport The directed movement of a virus, or part of a virus, into, out of, or within a host cell. GO:0046793 induction by virus of phosphorylation of host RNA polymerase II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046793 induction by virus of modification of host RNA polymerase II|virus-induced modification of host RNA polymerase II Any process in which a virus activates the frequency, rate or extent of phosphorylation of host RNA polymerase II. UBERON:0016928 metaphysis of fibula biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016928 fibular metaphysis|fibula metaphysis A metaphysis that is part of a fibula. GO:0071739 IgD immunoglobulin complex, circulating biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071739 IgD antibody A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. GO:0071738 IgD immunoglobulin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071738 A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgD immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. GO:0071737 IgG B cell receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071737 membrane-bound IgG2c|surface IgG4|membrane-bound IgG2b|surface IgG3|membrane-bound IgG2a|surface IgG2|surface IgG1|surface IgG|membrane-bound IgG|surface IgG2c|membrane-bound IgG4|surface IgG2b|membrane-bound IgG3|surface IgG2a|membrane-bound IgG2|membrane-bound IgG1 An IgG immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins. GO:0071736 IgG immunoglobulin complex, circulating biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071736 IgG1 antibody|IgG2 antibody|IgG antibody|IgG3 antibody|IgG4 antibody|IgG2a antibody|IgG2b antibody|IgG2c antibody A protein complex composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. GO:0071735 IgG immunoglobulin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071735 IgG2c|IgG2b|IgG2a|IgG4|IgG3|IgG2|IgG1 A protein complex composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgG immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. GO:0071734 biotin-[pyruvate-carboxylase] ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071734 EC:6.3.4.- biotin-[pyruvate carboxylase] synthetase activity|biotin-pyruvate carboxylase synthetase activity|biotin:apo-pyruvate-carboxylase ligase|biotin-pyruvate-carboxylase ligase activity|biotin-[pyruvate carboxylase] ligase activity Catalysis of the reaction: ATP + biotin + apo-(pyruvate-carboxylase) = AMP + diphosphate + biotin-(pyruvate-carboxylase). GO:0071733 transcriptional activation by promoter-enhancer looping biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071733 long-range enhancer-promoter communication The formation and maintenance of DNA loops that juxtapose the promoter and enhancer regions of RNA polymerase II-transcribed genes and activate transcription from an RNA polymerase II promoter. CHEBI:59758 omega-amino fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59758 GO:0071732 cellular response to nitric oxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071732 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus. GO:0071731 response to nitric oxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071731 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus. GO:0071730 beak formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071730 The process that gives rise to the beak. This process pertains to the initial formation of a structure from unspecified parts. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus. GO:0007199 G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger|GPCR signaling pathway via activation of guanylate cyclase activity|GPCR signaling pathway via cGMP second messenger|G protein signalling, coupled to cGMP nucleotide second messenger|G-protein signaling, coupled to cGMP nucleotide second messenger|G-protein signalling, coupled to cGMP nucleotide second messenger|guanylate cyclase-activating G-protein coupled receptor signaling pathway|G protein signaling, coupled to cGMP nucleotide second messenger The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, followed by activation of guanylyl cyclase (GC) activity and a subsequent increase in the concentration of cyclic GMP (cGMP). GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007198 inhibition of adenylate cyclase activity by serotonin receptor signaling pathway|serotonin receptor, adenylyl cyclase inhibiting pathway|inhibition of adenylate cyclase activity by serotonin receptor signalling pathway|serotonin receptor, adenylate cyclase inhibiting pathway The series of molecular signals generated as a consequence of a serotonin receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP). GO:0007197 adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007197 inhibition of adenylate cyclase activity by muscarinic acetylcholine receptor signalling pathway|muscarinic acetylcholine receptor, adenylate cyclase inhibiting pathway|inhibition of adenylate cyclase activity by G-protein coupled acetylcholine receptor signaling pathway|muscarinic acetylcholine receptor, adenylyl cyclase inhibiting pathway|inhibition of adenylate cyclase activity by muscarinic acetylcholine receptor signaling pathway The series of molecular signals generated as a consequence of a G protein-coupled acetylcholine receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP). GO:0007196 adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007196 inhibition of adenylate cyclase activity by metabotropic glutamate receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway|metabotropic glutamate receptor, adenylyl cyclase inhibiting pathway|inhibition of adenylate cyclase activity by G-protein-coupled glutamate receptor signaling pathway|inhibition of adenylate cyclase activity by metabotropic glutamate receptor signalling pathway|metabotropic glutamate receptor, adenylate cyclase inhibiting pathway The series of molecular signals generated as a consequence of a G protein-coupled glutamate receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP). GO:0032151 mitotic septin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032151 A heterooligomeric septin complex that acts during mitotic cell division. GO:0032150 ubiquinone biosynthetic process from chorismate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032150 The chemical reactions and pathways resulting in the formation of ubiquinone, beginning with the conversion of chorismate to 4-hydroxybenzoate. GO:0032159 septin cap biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032159 A faint structure formed of septins found at the leading edge of growth in germ tubes and hyphae in fungal cells growing filamentously. This cap of septins colocalizes with a region of the plasma membrane that is rich in ergosterol. GO:0032158 septin band biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032158 A diffuse ring composed of a series of septin bars that run parallel to the long axis of the cell. This type of septin structure has been observed in a number of locations associated with polarized grown and/or deposition of new membrane, but not with cytokinesis, such as at the shmoo (mating projection) neck, at the junction between the mother cell and the germ tube (hypha) of a fungal cell growing filamentously. GO:0032157 prospore contractile ring biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032157 meiotic contractile ring|cytokinetic ring|actomyosin ring A contractile ring, i.e. a cytoskeletal structure composed of actin filaments and myosin, that forms beneath the plasma membrane of the prospore envelope in meiotic cells in preparation for completing cytokinesis. GO:0032156 septin cytoskeleton biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032156 The part of the cytoskeleton (the internal framework of a cell) composed of septins and associated proteins. Includes septin cytoskeleton-associated complexes. GO:0032155 obsolete cell division site part biolink:CellularComponent go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0032155 cell division plane part OBSOLETE. Any constituent part of the cell division plane, the eventual plane of cell division in a dividing cell. GO:0032154 cleavage furrow biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032154 Wikipedia:Cleavage_furrow The cleavage furrow is a plasma membrane invagination at the cell division site. The cleavage furrow begins as a shallow groove and eventually deepens to divide the cytoplasm. GO:0032153 cell division site biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0032153 cell division plane The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles. GO:0032152 meiotic septin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032152 A heterooligomeric septin complex that acts during meiotic cell division. GO:0032149 response to rhamnose biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032149 response to L-rhamnose stimulus|response to rhamnose stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rhamnose stimulus. GO:0032140 single adenine insertion binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032140 Interacting selectively and non-covalently with double-stranded DNA containing a single adenine insertion or a deletion that results in an unpaired adenine. GO:0032148 activation of protein kinase B activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032148 protein kinase B activation Any process that initiates the activity of the inactive enzyme protein kinase B. GO:0032147 activation of protein kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032147 protein kinase activation Any process that initiates the activity of an inactive protein kinase. GO:0032146 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032146 GO:0032145 succinate-semialdehyde dehydrogenase binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032145 succinic semialdehyde dehydrogenase binding Interacting selectively and non-covalently with succinate-semialdehyde dehydrogenase. GO:0032144 4-aminobutyrate transaminase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032144 ABAT complex|GABA transaminase complex|GABA-T complex A homodimeric protein complex that possesses 4-aminobutyrate transaminase activity. GO:0032143 single thymine insertion binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032143 Interacting selectively and non-covalently with double-stranded DNA containing a single thymine insertion or a deletion that results in an unpaired thymine. GO:0032142 single guanine insertion binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032142 Interacting selectively and non-covalently with double-stranded DNA containing a single guanine insertion or a deletion that results in an unpaired guanine. GO:0032141 single cytosine insertion binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032141 Interacting selectively and non-covalently with double-stranded DNA containing a single cytosine insertion or a deletion that results in an unpaired cytosine. CHEBI:84729 hydroxyindoles biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84729 GO:0032139 dinucleotide insertion or deletion binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032139 dinucleotide insertion binding Interacting selectively and non-covalently with double-stranded DNA containing a dinucleotide insertion or deletion. GO:0032138 single base insertion or deletion binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032138 single base insertion binding Interacting selectively and non-covalently with double-stranded DNA containing a single base insertion or deletion. CHEBI:84726 UDP-N-acetyl-alpha-D-muramoyl-L-alanine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84726 CHEBI:84725 UDP-beta-L-rhamnose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84725 GO:0007179 transforming growth factor beta receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007179 transforming growth factor beta receptor signalling pathway|TGFbeta receptor signaling pathway|TGF-beta receptor signalling pathway|TGF-beta receptor signaling pathway|TGFbeta receptor signalling pathway A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007178 transmembrane receptor protein serine/threonine kinase signalling pathway A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses serine/threonine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0007177 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007177 GO:0007176 regulation of epidermal growth factor-activated receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007176 regulation of EGF receptor activity|regulation of epidermal growth factor receptor activity|regulation of EGFR activity Any process that modulates the frequency, rate or extent of EGF-activated receptor activity. GO:0007175 negative regulation of epidermal growth factor-activated receptor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007175 downregulation of epidermal growth factor receptor activity|negative regulation of epidermal growth factor receptor activity|negative regulation of EGFR activity|down-regulation of epidermal growth factor receptor activity|inhibition of epidermal growth factor receptor activity|negative regulation of EGF receptor activity|EGF receptor downregulation|down regulation of epidermal growth factor receptor activity Any process that stops, prevents, or reduces the frequency, rate or extent of EGF-activated receptor activity. GO:0007174 epidermal growth factor catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007174 EGF receptor ligand processing|intracellular EGF processing|receptor-mediated EGF processing|epidermal growth factor breakdown|epidermal growth factor ligand processing|EGF catabolism|EGF breakdown|epidermal growth factor catabolism The chemical reactions and pathways resulting in the breakdown of epidermal growth factor (EGF), following internalization of the receptor-bound ligand into the signal-receiving cell. Full breakdown of epidermal growth factor results in a ligand that is unable to bind and activate its receptor. GO:0007184 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007184 GO:0007183 SMAD protein complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007183 SMAD protein heteromerization The aggregation, arrangement and bonding together of a set of components to form a protein complex that contains SMAD proteins. CHEBI:60761 floxuridine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60761 GO:0007182 common-partner SMAD protein phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007182 common partner SMAD protein phosphorylation|common-mediator SMAD protein phosphorylation|co-SMAD protein phosphorylation|common mediator SMAD protein phosphorylation The process of introducing a phosphate group on to a common-partner SMAD protein. A common partner SMAD protein binds to pathway-restricted SMAD proteins forming a complex that translocates to the nucleus. GO:0007181 transforming growth factor beta receptor complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007181 TGF-beta:type II receptor:type I receptor complex assembly|TGF-beta receptor complex assembly|TGFbeta receptor complex assembly The aggregation, arrangement and bonding together of a ligand-bound type II transforming growth factor beta (TGF-beta) receptor dimer with a type I TGF-beta receptor dimer, following ligand binding, to form a heterotetrameric TGF-beta receptor complex. GO:0007180 obsolete transforming growth factor beta ligand binding to type II receptor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007180 TGFbeta ligand binding to type II receptor|TGF-beta ligand binding to type II receptor|transforming growth factor beta ligand binding to type II receptor OBSOLETE. (Was not defined before being made obsolete). GO:0032137 guanine/thymine mispair binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032137 thymine/guanine mispair binding|G/T mispair binding|T/G mispair binding Interacting selectively and non-covalently with double-stranded DNA containing a G/T mispair. GO:0032136 adenine/cytosine mispair binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032136 cytosine/adenine mispair binding|C/A mispair binding|A/C mispair binding Interacting selectively and non-covalently with double-stranded DNA containing an A/C mispair. GO:0032135 DNA insertion or deletion binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032135 insertion binding|DNA insertion binding Interacting selectively and non-covalently with double-stranded DNA containing insertions or deletions. GO:0032134 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032134 GO:0032133 chromosome passenger complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032133 CPC|chromosomal passenger complex|CPC complex A eukaryotically conserved protein complex that localizes to kinetochores in early mitosis, the spindle mid-zone in anaphase B and to the telophase midbody. It has been proposed that the passenger complex coordinates various events based on its location to different structures during the course of mitosis. Complex members include the BIR-domain-containing protein Survivin, Aurora kinase, INCENP and Borealin. GO:0032132 O6-alkylguanine-DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032132 Interacting selectively and non-covalently with O6-alkylguanine adducts in DNA. GO:0032131 alkylated DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032131 Interacting selectively and non-covalently with alkylated residues in DNA. GO:0032130 medial membrane band assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032130 medial membrane band formation The assembly of a sterol-rich region of the plasma membrane at the cell surface overlying the contractile ring. GO:0032129 histone deacetylase activity (H3-K9 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032129 Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 9) + H2O = histone H3 L-lysine (position 9) + acetate. This reaction represents the removal of an acetyl group from lysine at position 9 of the histone H3 protein. GO:0032128 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032128 GO:0032127 dense core granule membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032127 dense core vesicle membrane The lipid bilayer surrounding a dense core granule. CHEBI:84735 algal metabolite biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84735 GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007189 G protein signalling, adenylate cyclase activating pathway|activation of adenylate cyclase activity by G-protein signaling pathway|GPCR signaling pathway via activation of adenylate cyclase activity|positive regulation of adenylate cyclase activity by G-protein signalling pathway|activation of adenylate cyclase activity involved in G-protein signaling|G protein signalling, adenylyl cyclase activating pathway|G protein signaling, adenylate cyclase activating pathway|G-protein signaling, adenylate cyclase activating pathway|G-protein signaling, adenylyl cyclase activating pathway|G-protein signalling, adenylate cyclase activating pathway|positive regulation of adenylate cyclase activity by G-protein signaling pathway|GPCR signaling pathway via activation of adenylate cyclase|positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway|G-protein signalling, adenylyl cyclase activating pathway|adenylate cyclase-activating GPCR signaling pathway|G protein signaling, adenylyl cyclase activating pathway The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through activation of adenylyl cyclase activity and a subsequent increase in the concentration of cyclic AMP (cAMP). CHEBI:84734 Fe(III)-complexed siderophore biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84734 GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007188 GPCR signaling pathway via modulation of adenylate cyclase activity|G protein signalling, coupled to cAMP nucleotide second messenger|adenylate cyclase-modulating GPCR signaling pathway|G protein signalling, coupled to cyclic AMP nucleotide second messenger|G-protein signaling, coupled to cyclic AMP nucleotide second messenger|G-protein signaling, coupled to cAMP nucleotide second messenger|G-protein signalling, coupled to cAMP nucleotide second messenger|G protein signaling, coupled to cAMP nucleotide second messenger|G-protein signalling, coupled to cyclic AMP nucleotide second messenger|GPCR signaling pathway via cAMP second messenger|G protein signaling, coupled to cyclic AMP nucleotide second messenger The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through activation or inhibition of adenylyl cyclase activity and a subsequent change in the concentration of cyclic AMP (cAMP). CHEBI:84733 dihexosylceramide sulfate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84733 CHEBI:84732 sulfohexosyl ceramide(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84732 GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007187 G protein signalling, coupled to cyclic nucleotide second messenger|G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger|G-protein signaling, coupled to cyclic nucleotide second messenger|G-protein signalling, coupled to cyclic nucleotide second messenger|G protein signaling, coupled to cyclic nucleotide second messenger|GPCR signaling pathway via cyclic nucleotide second messenger The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds with activation or inhibition of a nucleotide cyclase activity and a subsequent change in the concentration of a cyclic nucleotide. GO:0007186 G protein-coupled receptor signaling pathway biolink:BiologicalProcess go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0007186 G protein coupled receptor protein signalling pathway|dimeric G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway via GPCR dimer|G protein coupled receptor protein signaling pathway|G-protein coupled receptor protein signal transduction|G-protein coupled receptor protein signaling pathway|GPCR signalling pathway|G-protein coupled receptor signalling pathway|dimeric G-protein coupled receptor signalling pathway|G-protein-coupled receptor protein signalling pathway|GPCR signaling pathway A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane. GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007185 transmembrane receptor protein tyrosine phosphatase signalling pathway A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses protein tyrosine phosphatase activity, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007195 dopamine receptor, adenylyl cyclase inhibiting pathway|inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|dopamine receptor, adenylate cyclase inhibiting pathway|inhibition of adenylate cyclase activity by dopamine receptor signaling pathway The series of molecular signals generated as a consequence of a dopamine receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP). GO:0007194 negative regulation of adenylate cyclase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007194 down-regulation of adenylate cyclase activity|downregulation of adenylate cyclase activity|down regulation of adenylate cyclase activity|inhibition of adenylate cyclase activity|adenylate cyclase inhibitor|negative regulation of adenylyl cyclase activity Any process that stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase activity. GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007193 G protein signalling, adenylate cyclase inhibiting pathway|GPCR signaling pathway via inhibition of adenylate cyclase activity|inhibition of adenylate cyclase activity by G-protein signaling pathway|G protein signalling, adenylyl cyclase inhibiting pathway|G protein signaling, adenylate cyclase inhibiting pathway|G-protein signaling, adenylyl cyclase inhibiting pathway|G-protein signaling, adenylate cyclase inhibiting pathway|G-protein signalling, adenylate cyclase inhibiting pathway|adenylate cyclase-inhibiting GPCR signaling pathway|G-protein signalling, adenylyl cyclase inhibiting pathway|G protein signaling, adenylyl cyclase inhibiting pathway The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through inhibition of adenylyl cyclase activity and a subsequent decrease in the concentration of cyclic AMP (cAMP). GO:0007192 adenylate cyclase-activating serotonin receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007192 serotonin receptor, adenylate cyclase activating pathway|activation of adenylate cyclase activity by serotonin receptor signalling pathway|serotonin receptor, adenylyl cyclase activating pathway The series of molecular signals generated as a consequence of a serotonin receptor binding to its physiological ligand, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP). GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007191 activation of adenylate cyclase activity by dopamine receptor signalling pathway|dopamine receptor, adenylate cyclase activating pathway|activation of adenylate cyclase activity by dopamine receptor signaling pathway|dopamine receptor, adenylyl cyclase activating pathway The series of molecular signals generated as a consequence of a dopamine receptor binding to its physiological ligand, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP). GO:0007190 activation of adenylate cyclase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007190 adenylate cyclase activation|adenylate cyclase activator|adenylyl cyclase activation Any process that initiates the activity of the inactive enzyme adenylate cyclase. GO:0032126 eisosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032126 Wikipedia:Eisosome A cell part that is composed of the eisosome membrane or MCC domain, a furrow-like plasma membrane sub-domain and associated integral transmembrane proteins, and the proteins (eisosome filaments) that form a scaffolding lattice on the cytoplasmic face. Eisosomes broadly affect overall plasma membrane organization. GO:0032125 micronucleus organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032125 micronucleus organisation|micronuclear organization|micronuclear organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the micronucleus. GO:0032124 macronucleus organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032124 macronuclear organization and biogenesis|macronuclear organization|macronucleus organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the macronucleus. GO:0032123 deep fiber biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032123 deep fibre Inward projections of the cytoskeletal structures of the oral apparatus, which form a fiber that extends past the cytostome into the cytoplasm. GO:0032122 oral apparatus organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032122 oral apparatus organisation|stomatogenesis|oral apparatus organization and biogenesis|oral apparatus morphogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the oral apparatus. The oral apparatus is a funnel-like structure used by the cell to collect food and channel it to the cytostome, characteristic of ciliate protozoans. GO:0032121 meiotic attachment of telomeric heterochromatin to spindle pole body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032121 attachment of telomeric chromatin to spindle pole body|attachment of telomeres to spindle pole body The meiotic cell cycle process in which physical connections are formed between telomeric heterochromatin and the spindle pole body, facilitating bouquet formation. GO:0032120 ascospore-type prospore membrane formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032120 FSM assembly|ascospore-type prospore membrane assembly|forespore membrane biosynthesis|prospore membrane biogenesis|forespore membrane formation|FSM formation|FSM biosynthesis The process in which the nascent membrane forms at the meiotic outer plaque and grows until closure occurs and forespores, or prospores, are formed. GO:0032119 sequestering of zinc ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032119 The process of binding or confining zinc ions such that they are separated from other components of a biological system. GO:0032118 horsetail-astral microtubule organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032118 horsetail-astral microtubule organization and biogenesis|horsetail-astral microtubule array organization|horsetail-astral microtubule organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the horsetail-astral array, a structure of astral microtubules that emanates from the spindle pole body during meiosis. GO:0032117 horsetail-astral microtubule array biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032117 HAA An array of astral microtubules that emanates from the spindle pole body during meiosis and facilitates horsetail nuclear movement. GO:0032116 SMC loading complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032116 chromatin loading complex|SCC2/SCC4 loading complex|cohesin loading complex A protein complex required for the loading of a structural maintenance of chromosome (SMC) complex, such as cohesin, condensin or SMC5/SMC6, onto DNA. Appears to be eukaryotically conserved. GO:0007159 leukocyte cell-cell adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007159 leukocyte adhesion|leukocyte cell adhesion The attachment of a leukocyte to another cell via adhesion molecules. GO:0007158 neuron cell-cell adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007158 neuron adhesion|neuronal cell adhesion The attachment of a neuron to another cell via adhesion molecules. GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007157 agglutination The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell. GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007156 The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell. CHEBI:84745 amiloride(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84745 GO:0007155 cell adhesion biolink:BiologicalProcess go-plus goslim_candida|goslim_pir|goslim_drosophila|goslim_aspergillus|goslim_metagenomics|goslim_generic|goslim_pombe|goslim_chembl http://purl.obolibrary.org/obo/GO_0007155 Wikipedia:Cell_adhesion single organism cell adhesion|cell adhesion molecule activity The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. GO:0007154 cell communication biolink:BiologicalProcess go-plus goslim_plant|goslim_pir http://purl.obolibrary.org/obo/GO_0007154 Wikipedia:Cell_signaling Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. GO:0007153 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007153 GO:0007152 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007152 CHEBI:60784 3'-UMP(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60784 GO:0007162 negative regulation of cell adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007162 cell adhesion receptor inhibitor activity|down-regulation of cell adhesion|inhibition of cell adhesion|down regulation of cell adhesion|downregulation of cell adhesion Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion. GO:0007161 calcium-independent cell-matrix adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007161 calcium-independent cell adhesion molecule activity The binding of a cell to the extracellular matrix via adhesion molecules that do not require the presence of calcium for the interaction. CHEBI:60783 nucleoside analogue biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60783 GO:0007160 cell-matrix adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007160 The binding of a cell to the extracellular matrix via adhesion molecules. CHEBI:3900 costunolide biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_3900 GO:0032115 sorbose reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032115 RHEA:14609|KEGG_REACTION:R07346|MetaCyc:1.1.1.289-RXN|EC:1.1.1.289 Sou1p|D-glucitol:NADP+ oxidoreductase activity Catalysis of the reaction: D-glucitol + NADP(+) = L-sorbose + H(+) + NADPH. The reaction may occur, to a minor extent, in the reverse direction. GO:0032114 regulation of glucose-6-phosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032114 Any process that modulates the frequency, rate or extent of glucose-6-phosphatase activity, the catalysis of the reaction: D-glucose 6-phosphate + H2O = D-glucose + phosphate. GO:0032113 regulation of carbohydrate phosphatase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032113 Any process that modulates the frequency, rate or extent of carbohydrate phosphatase activity, the catalysis of the hydrolysis of phosphate from a carbohydrate phosphate. GO:0032112 negative regulation of protein histidine kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032112 down-regulation of protein histidine kinase activity|inhibition of protein histidine kinase activity|protein histidine kinase inhibitor|down regulation of protein histidine kinase activity|downregulation of protein histidine kinase activity Any process that stops, prevents, or reduces the frequency, rate or extent of protein histidine kinase activity. GO:0032111 activation of protein histidine kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032111 protein histidine kinase activator Any process that initiates the activity of an inactive protein histidine kinase. GO:0032110 regulation of protein histidine kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032110 Any process that modulates the frequency, rate or extent of protein histidine kinase activity. GO:0032109 positive regulation of response to nutrient levels biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032109 up regulation of response to nutrient levels|activation of response to nutrient levels|stimulation of response to nutrient levels|up-regulation of response to nutrient levels|upregulation of response to nutrient levels Any process that activates or increases the frequency, rate or extent of a response to nutrient levels. GO:0032108 negative regulation of response to nutrient levels biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032108 downregulation of response to nutrient levels|down-regulation of response to nutrient levels|inhibition of response to nutrient levels|down regulation of response to nutrient levels Any process that stops, prevents, or reduces the frequency, rate or extent of a response to nutrient levels. GO:0032107 regulation of response to nutrient levels biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032107 Any process that modulates the frequency, rate or extent of a response to nutrient levels. GO:0032106 positive regulation of response to extracellular stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032106 stimulation of response to extracellular stimulus|up-regulation of response to extracellular stimulus|activation of response to extracellular stimulus|up regulation of response to extracellular stimulus|upregulation of response to extracellular stimulus Any process that activates, maintains or increases the rate of a response to an extracellular stimulus. GO:0032105 negative regulation of response to extracellular stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032105 down-regulation of response to extracellular stimulus|downregulation of response to extracellular stimulus|down regulation of response to extracellular stimulus|inhibition of response to extracellular stimulus Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an extracellular stimulus. GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007169 transmembrane receptor protein tyrosine kinase signalling pathway A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0007168 receptor guanylyl cyclase signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007168 receptor guanylyl cyclase signalling pathway A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses guanylyl cyclase activity, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0007167 enzyme linked receptor protein signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007167 enzyme linked receptor protein signalling pathway Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell, where the receptor possesses catalytic activity or is closely associated with an enzyme such as a protein kinase, and ending with regulation of a downstream cellular process, e.g. transcription. CHEBI:84756 2-deoxy-D-glucopyranose 6-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84756 GO:0007166 cell surface receptor signaling pathway biolink:BiologicalProcess go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0007166 cell surface receptor linked signalling pathway|cell surface receptor linked signal transduction|cell surface receptor linked signaling pathway A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription. CHEBI:84755 2-deoxy-D-glucopyranose biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84755 CHEBI:3918 crocetin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_3918 GO:0007165 signal transduction biolink:BiologicalProcess go-plus goslim_chembl|goslim_candida|goslim_plant|goslim_aspergillus|goslim_metagenomics|goslim_generic http://purl.obolibrary.org/obo/GO_0007165 Wikipedia:Signal_transduction signalling cascade|signal transduction by protein phosphorylation|signaling cascade|signal transduction by cis-phosphorylation|signal transduction by trans-phosphorylation|signal transduction by conformational transition|signalling pathway|signaling pathway The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. GO:0007164 establishment of tissue polarity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007164 Coordinated organization of groups of cells in a tissue, such that they all orient to similar coordinates. GO:0007163 establishment or maintenance of cell polarity biolink:BiologicalProcess go-plus goslim_pombe http://purl.obolibrary.org/obo/GO_0007163 cell polarity|establishment and/or maintenance of cell polarity|establishment and/or maintenance of cell polarization Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns. GO:0007173 epidermal growth factor receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007173 ERBB1 signaling pathway|EGF receptor signaling pathway|epidermal growth factor receptor signalling pathway|EGFR signaling pathway|receptor tyrosine-protein kinase erbB-1 signaling pathway|EGF receptor signalling pathway A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor EGFR (ERBB1) on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription. GO:0007172 signal complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007172 signal complex formation The aggregation, arrangement and bonding together of a set of components to form a complex capable of relaying a signal within a cell. GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007171 transmembrane receptor protein tyrosine kinase activation|transmembrane receptor protein tyrosine kinase dimerization Any process that initiates the activity of the inactive transmembrane receptor protein tyrosine kinase activity. GO:0007170 obsolete transmembrane receptor protein tyrosine kinase ligand binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007170 transmembrane receptor protein tyrosine kinase ligand binding OBSOLETE. (Was not defined before being made obsolete). CHEBI:60798 excitatory amino acid antagonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60798 GO:0032104 regulation of response to extracellular stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032104 Any process that modulates the frequency, rate or extent of a response to an extracellular stimulus. GO:0032103 positive regulation of response to external stimulus biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0032103 stimulation of response to external stimulus|up-regulation of response to external stimulus|upregulation of response to external stimulus|up regulation of response to external stimulus|activation of response to external stimulus Any process that activates, maintains or increases the rate of a response to an external stimulus. GO:0032102 negative regulation of response to external stimulus biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0032102 down-regulation of response to external stimulus|inhibition of response to external stimulus|down regulation of response to external stimulus|downregulation of response to external stimulus Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus. GO:0032101 regulation of response to external stimulus biolink:BiologicalProcess go-plus gocheck_do_not_manually_annotate http://purl.obolibrary.org/obo/GO_0032101 Any process that modulates the frequency, rate or extent of a response to an external stimulus. GO:0032100 positive regulation of appetite biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032100 positive regulation of hunger|up regulation of appetite|appetite stimulation|upregulation of appetite|stimulation of appetite|up-regulation of appetite|activation of appetite Any process that increases appetite. GO:0007139 meiotic telophase II biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0007139 The cell cycle phase which follows anaphase II of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts. GO:0007138 meiotic anaphase II biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0007138 The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of meiosis II. GO:0046701 insecticide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046701 insecticide degradation|insecticide breakdown|insecticide catabolism The chemical reactions and pathways resulting in the breakdown of insecticides, chemicals used to kill insects. GO:0007137 meiotic metaphase II biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0007137 The cell cycle phase, following prophase II, during which chromosomes become aligned on the equatorial plate of the cell as part of meiosis II. GO:0046700 heterocycle catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046700 heterocycle degradation|heterocycle breakdown|heterocycle catabolism The chemical reactions and pathways resulting in the breakdown of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings). GO:0007136 meiotic prophase II biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0007136 The cell cycle phase which is the first stage of meiosis II and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell. GO:0007135 meiosis II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007135 Wikipedia:Meiosis#Meiosis_II meiosis II nuclear division The second nuclear division of meiosis, in which the two chromatids in each chromosome are separated, resulting in four daughter nuclei from the two nuclei produced in meiosis II. GO:0007134 meiotic telophase I biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0007134 The cell cycle phase which follows anaphase I of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts. GO:0007133 meiotic anaphase I biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0007133 The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of meiosis I. CHEBI:69136 latrunculin A biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_69136 GO:0007132 meiotic metaphase I biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0007132 The cell cycle phase, following prophase I, during which chromosomes become aligned on the equatorial plate of the cell as part of meiosis I. GO:0007131 reciprocal meiotic recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007131 gene conversion with reciprocal crossover|female meiotic recombination The cell cycle process in which double strand breaks are formed and repaired through a single or double Holliday junction intermediate. This results in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. These reciprocal recombinant products ensure the proper segregation of homologous chromosomes during meiosis I and create genetic diversity. GO:0007130 synaptonemal complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007130 synaptonemal complex formation The cell cycle process in which the synaptonemal complex is formed. This is a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination. GO:0007140 male meiotic nuclear division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007140 male nuclear division|male meiosis A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline. GO:0046709 IDP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046709 IDP degradation|IDP catabolism|IDP breakdown The chemical reactions and pathways resulting in the breakdown of IDP, inosine 5'-diphosphate. GO:0046708 IDP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046708 IDP biosynthesis|IDP anabolism|IDP synthesis|IDP formation The chemical reactions and pathways resulting in the formation of IDP, inosine 5'-diphosphate. CHEBI:84760 2-deoxy-D-glucopyranose 6-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84760 GO:0046707 IDP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046707 IDP metabolism The chemical reactions and pathways involving IDP, inosine 5'-diphosphate. GO:0046706 CDP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046706 CDP catabolism|CDP degradation|CDP breakdown The chemical reactions and pathways resulting in the breakdown of CDP, cytidine (5'-)diphosphate. GO:0046705 CDP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046705 CDP synthesis|CDP formation|CDP biosynthesis|CDP anabolism The chemical reactions and pathways resulting in the formation of CDP, cytidine (5'-)diphosphate. GO:0046704 CDP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046704 CDP metabolism The chemical reactions and pathways involving CDP, cytidine (5'-)diphosphate. GO:0046703 natural killer cell lectin-like receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046703 NKG2D receptor binding|NK cell lectin-like receptor binding|KLRC4 receptor binding Interacting selectively and non-covalently with a lectin-like natural killer cell receptor. GO:0046702 galactoside 6-L-fucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046702 Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to a galactoside acceptor molecule, usually an N-glycan, to form an alpha(1,6)-fucosylated galactoside. GO:0007149 obsolete colony morphology biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007149 colony morphology OBSOLETE. (Was not defined before being made obsolete). GO:0046712 GDP catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046712 GDP catabolism|GDP degradation|GDP breakdown The chemical reactions and pathways resulting in the breakdown of GDP, guanosine 5'-diphosphate. GO:0007148 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007148 GO:0046711 GDP biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046711 GDP anabolism|GDP synthesis|GDP formation|GDP biosynthesis The chemical reactions and pathways resulting in the formation of GDP, guanosine 5'-diphosphate. GO:0007147 female meiosis II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007147 female meiosis II nuclear division The cell cycle process in which the second meiotic division occurs in the female germline. GO:0046710 GDP metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046710 GDP metabolism The chemical reactions and pathways involving GDP, guanosine 5'-diphosphate. GO:0007146 meiotic recombination nodule assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007146 During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form small, electron dense structures in association with meiotic chromosomes. GO:0007145 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007145 GO:0007144 female meiosis I biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007144 female meiosis I nuclear division The cell cycle process in which the first meiotic division occurs in the female germline. GO:0007143 female meiotic nuclear division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007143 female meiosis|female meiotic division A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline. GO:0007142 male meiosis II biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007142 male meiosis II nuclear division A cell cycle process comprising the steps by which a cell progresses through male meiosis II, the second meiotic division in the male germline. GO:0007141 male meiosis I biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007141 male meiosis I nuclear division A cell cycle process comprising the steps by which a cell progresses through male meiosis I, the first meiotic division in the male germline. GO:0007151 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007151 GO:0046719 regulation by virus of viral protein levels in host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046719 regulation of viral protein levels Any virus-mediated process that modulates the levels of viral proteins in a cell. GO:0007150 obsolete growth pattern biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007150 growth pattern OBSOLETE. A process whereby cells develop a specific morphology under a specific set of circumstances. GO:0046718 viral entry into host cell biolink:BiologicalProcess go-plus goslim_metagenomics http://purl.obolibrary.org/obo/GO_0046718 VZ:936 virion penetration into host cell|phage translocation|virus entry into host cell|entry of virus into host cell|viral penetration|virion penetration The process that occurs after viral attachment by which a virus, or viral nucleic acid, breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the viral nucleic acid is released into the host cell cytoplasm. GO:0046717 acid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046717 The controlled release of acid by a cell or a tissue. GO:0046716 muscle cell cellular homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046716 muscle homeostasis|muscle fiber maintenance The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state. GO:0046715 active borate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046715 efflux-type boron transporter|efflux-type borate transporter|borate transmembrane transporter activity|borate uptake transmembrane transporter activity|boron uptake transmembrane transporter activity|boron transmembrane transporter activity Enables the transport of borate across a membrane against the concentration gradient. GO:0046714 borate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046714 boron binding Interacting selectively and non-covalently with borate, the anion (BO3)3-. GO:0046713 borate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046713 boron transport The directed movement of borate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Borate is the anion (BO3)3-; boron is a group 13 element, with properties which are borderline between metals and non-metals. GO:1900598 demethylkotanin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900598 demethylkotanin catabolism|demethylkotanin degradation|demethylkotanin breakdown The chemical reactions and pathways resulting in the breakdown of demethylkotanin. GO:1900597 demethylkotanin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900597 demethylkotanin metabolism The chemical reactions and pathways involving demethylkotanin. GO:1900599 demethylkotanin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900599 demethylkotanin biosynthesis|demethylkotanin anabolism|demethylkotanin synthesis|demethylkotanin formation The chemical reactions and pathways resulting in the formation of demethylkotanin. GO:1900594 (+)-kotanin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900594 (+)-kotanin metabolism The chemical reactions and pathways involving (+)-kotanin. GO:1900593 violaceol II biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900593 violaceol II anabolism|violaceol II synthesis|violaceol II formation|violaceol II biosynthesis The chemical reactions and pathways resulting in the formation of violaceol II. GO:1900596 (+)-kotanin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900596 (+)-kotanin synthesis|(+)-kotanin formation|(+)-kotanin anabolism|(+)-kotanin biosynthesis The chemical reactions and pathways resulting in the formation of (+)-kotanin. GO:1900595 (+)-kotanin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900595 (+)-kotanin degradation|(+)-kotanin breakdown|(+)-kotanin catabolism The chemical reactions and pathways resulting in the breakdown of (+)-kotanin. CHEBI:3941 cucurbitacin B biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_3941 CHEBI:35704 N(2)-acetyl-L-lysine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35704 CHEBI:35703 xenobiotic biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35703 CHEBI:35705 immunosuppressive agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35705 CHEBI:35709 thujane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35709 CHEBI:35701 ester biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35701 GO:0032096 negative regulation of response to food biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032096 down regulation of response to food|inhibition of response to food|down-regulation of response to food|downregulation of response to food Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a food stimulus. GO:0032095 regulation of response to food biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032095 Any process that modulates the frequency, rate or extent of a response to a food stimulus. GO:0032094 response to food biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032094 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat. GO:0032093 SAM domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032093 Sterile Alpha Motif domain binding Interacting selectively and non-covalently with a SAM (Sterile Alpha Motif) domain, which is a 70-amino acid protein sequence that participates in protein-protein, protein-lipid, and protein-RNA interactions and is conserved from lower to higher eukaryotes. GO:0032092 positive regulation of protein binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032092 up regulation of protein binding|activation of protein binding|stimulation of protein binding|up-regulation of protein binding|upregulation of protein binding Any process that activates or increases the frequency, rate or extent of protein binding. GO:0032091 negative regulation of protein binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032091 downregulation of protein binding|down-regulation of protein binding|inhibition of protein binding|down regulation of protein binding Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding. GO:0032090 Pyrin domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032090 PAAD domain binding|DAPIN domain binding Interacting selectively and non-covalently with a Pyrin (PAAD/DAPIN) domain, a protein-protein interaction domain that has the same fold as the Death domain. GO:0032099 negative regulation of appetite biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032099 appetite suppression|negative regulation of hunger|down-regulation of appetite|downregulation of appetite|down regulation of appetite|inhibition of appetite Any process that reduces appetite. GO:0032098 regulation of appetite biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032098 regulation of hunger Any process which modulates appetite, the desire or physical craving for food. GO:0032097 positive regulation of response to food biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032097 upregulation of response to food|stimulation of response to food|up-regulation of response to food|activation of response to food|up regulation of response to food Any process that activates, maintains, or increases the rate of a response to a food stimulus. GO:0032085 regulation of type II site-specific deoxyribonuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032085 regulation of type II restriction endodeoxyribonuclease activity|type II restriction endodeoxyribonuclease regulator|type II restriction enzyme regulator Any process that modulates the frequency, rate or extent of a type II restriction endodeoxyribonuclease activity. GO:0032084 regulation of type I site-specific deoxyribonuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032084 type I restriction endodeoxyribonuclease regulator|regulation of type I restriction endodeoxyribonuclease activity|type I restriction enzyme regulator Any process that modulates the frequency, rate or extent of a type I restriction endodeoxyribonuclease activity. GO:0032083 negative regulation of type IV site-specific deoxyribonuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032083 downregulation of type IV restriction endodeoxyribonuclease activity|type IV restriction enzyme inhibitor|down regulation of type IV restriction endodeoxyribonuclease activity|inhibition of type IV restriction endodeoxyribonuclease activity|type IV restriction endodeoxyribonuclease inhibitor|negative regulation of type IV restriction endodeoxyribonuclease activity|down-regulation of type IV restriction endodeoxyribonuclease activity Any process that stops or reduces the rate of type IV restriction endodeoxyribonuclease activity. GO:0032082 negative regulation of type III site-specific deoxyribonuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032082 down-regulation of type III restriction endodeoxyribonuclease activity|inhibition of type III restriction endodeoxyribonuclease activity|type III restriction enzyme inhibitor|down regulation of type III restriction endodeoxyribonuclease activity|type III restriction endodeoxyribonuclease inhibitor|negative regulation of type III restriction endodeoxyribonuclease activity|downregulation of type III restriction endodeoxyribonuclease activity Any process that stops or reduces the rate of type III restriction endodeoxyribonuclease activity. GO:0032081 negative regulation of type II site-specific deoxyribonuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032081 down-regulation of type II restriction endodeoxyribonuclease activity|downregulation of type II restriction endodeoxyribonuclease activity|type II restriction endodeoxyribonuclease inhibitor|type II restriction enzyme inhibitor|down regulation of type II restriction endodeoxyribonuclease activity|inhibition of type II restriction endodeoxyribonuclease activity|negative regulation of type II restriction endodeoxyribonuclease activity Any process that stops or reduces the rate of type II restriction endodeoxyribonuclease activity. GO:0032080 negative regulation of type I site-specific deoxyribonuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032080 down-regulation of type I restriction endodeoxyribonuclease activity|inhibition of type I restriction endodeoxyribonuclease activity|type I restriction enzyme inhibitor|down regulation of type I restriction endodeoxyribonuclease activity|type I restriction endodeoxyribonuclease inhibitor|negative regulation of type I restriction endodeoxyribonuclease activity|downregulation of type I restriction endodeoxyribonuclease activity Any process that stops or reduces the rate of type I restriction endodeoxyribonuclease activity. GO:0032089 NACHT domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032089 Interacting selectively and non-covalently with a NACHT (NAIP, CIITA, HET-E and TP1) domain. The NACHT domain consists of seven distinct conserved motifs, including an ATP/GTPase specific P-loop, a Mg(2+)-binding site and five more specific motifs. GO:0032088 negative regulation of NF-kappaB transcription factor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032088 inhibition of NF-kappaB transcription factor|NF-kappaB inhibitor Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB. GO:0032087 regulation of type IV site-specific deoxyribonuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032087 type IV restriction enzyme regulator|regulation of type IV restriction endodeoxyribonuclease activity|type IV restriction endodeoxyribonuclease regulator Any process that modulates the frequency, rate or extent of a type IV restriction endodeoxyribonuclease activity. GO:0032086 regulation of type III site-specific deoxyribonuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032086 type III restriction endodeoxyribonuclease regulator|regulation of type III restriction endoribonuclease activity|type III restriction enzyme regulator Any process that modulates the frequency, rate or extent of a type III restriction endodeoxyribonuclease activity. GO:0032074 negative regulation of nuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032074 down-regulation of nuclease activity|inhibition of nuclease activity|nuclease inhibitor|down regulation of nuclease activity|downregulation of nuclease activity Any process that stops or reduces the rate of nuclease activity, the hydrolysis of ester linkages within nucleic acids. GO:0032073 negative regulation of restriction endodeoxyribonuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032073 restriction enzyme inhibitor|down regulation of restriction endodeoxyribonuclease activity|inhibition of restriction endodeoxyribonuclease activity|restriction alleviation|restriction endodeoxyribonuclease inhibitor|down-regulation of restriction endodeoxyribonuclease activity|downregulation of restriction endodeoxyribonuclease activity Any process that stops or reduces the rate of a restriction endodeoxyribonuclease activity, the catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks. GO:0032072 regulation of restriction endodeoxyribonuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032072 Any process that modulates the frequency, rate or extent of a restriction endodeoxyribonuclease activity, the catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks. GO:0032071 regulation of endodeoxyribonuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032071 endodeoxyribonuclease regulator Any process that modulates the frequency, rate or extent of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks. GO:0032070 regulation of deoxyribonuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032070 deoxyribonuclease regulator|DNase regulator Any process that modulates the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid. GO:0032079 positive regulation of endodeoxyribonuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032079 stimulation of endodeoxyribonuclease activity|up-regulation of endodeoxyribonuclease activity|activation of endodeoxyribonuclease activity|endodeoxyribonuclease activator|up regulation of endodeoxyribonuclease activity|upregulation of endodeoxyribonuclease activity Any process that activates or increases the frequency, rate or extent of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks. GO:0032078 negative regulation of endodeoxyribonuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032078 down-regulation of endodeoxyribonuclease activity|downregulation of endodeoxyribonuclease activity|down regulation of endodeoxyribonuclease activity|endodeoxyribonuclease inhibitor|inhibition of endodeoxyribonuclease activity Any process that stops or reduces the rate of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks. GO:0032077 positive regulation of deoxyribonuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032077 DNase activator|up regulation of deoxyribonuclease activity|upregulation of deoxyribonuclease activity|stimulation of deoxyribonuclease activity|up-regulation of deoxyribonuclease activity|activation of deoxyribonuclease activity|deoxyribonuclease activator Any process that activates or increases the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid. GO:0032076 negative regulation of deoxyribonuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032076 deoxyribonuclease inhibitor|downregulation of deoxyribonuclease activity|down regulation of deoxyribonuclease activity|DNase inhibitor|inhibition of deoxyribonuclease activity|down-regulation of deoxyribonuclease activity Any process that stops or reduces the rate of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid. GO:0032075 positive regulation of nuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032075 up regulation of nuclease activity|activation of nuclease activity|stimulation of nuclease activity|nuclease activator|up-regulation of nuclease activity|upregulation of nuclease activity Any process that activates or increases the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids. GO:0032063 negative regulation of translational initiation in response to osmotic stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032063 down regulation of translation initiation in response to osmotic stress|inhibition of translation initiation in response to osmotic stress|down-regulation of translation initiation in response to osmotic stress|downregulation of translation initiation in response to osmotic stress Any process that stops, prevents or reduces the rate of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. GO:0032062 positive regulation of translation in response to osmotic stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032062 up regulation of translation in response to osmotic stress|activation of translation in response to osmotic stress|stimulation of translation in response to osmotic stress|up-regulation of translation in response to osmotic stress|upregulation of translation in response to osmotic stress Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. GO:0032061 negative regulation of translation in response to osmotic stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032061 downregulation of translation in response to osmotic stress|down-regulation of translation in response to osmotic stress|inhibition of translation in response to osmotic stress|down regulation of translation in response to osmotic stress Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. GO:0032060 bleb assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032060 plasma membrane blebbing|cell blebbing|plasma membrane bleb assembly|membrane blebbing|blebbing The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses. GO:0032069 regulation of nuclease activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032069 nuclease regulator activity Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids. GO:0032068 type IV site-specific deoxyribonuclease complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032068 type IV restriction enzyme complex A complex consisting of two proteins which acts as an endonuclease in DNA sequences containing a specific modified recognition site. Modifications may include methylation, hydroxymethylation, and glucosyl-hydroxymethylation. GO:0032067 type IV site-specific deoxyribonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032067 type IV restriction enzyme activity Catalysis of the endonucleolytic cleavage of DNA in a site specific manner. Cleavage is dependent on the presence of a specific recognition site in the DNA which must be modified (e.g. methylated, hydroxymethylated, glucosyl-hydroxymethylated). GO:0032066 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032066 GO:0032065 maintenance of protein location in cell cortex biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032065 maintenance of protein location in cell cortex|cortical protein anchoring A process in which a protein or protein complex is maintained in a specific location in the cell cortex. CHEBI:3992 cyclic ketone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_3992 GO:0032064 positive regulation of translational initiation in response to osmotic stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032064 upregulation of translation initiation in response to osmotic stress|stimulation of translation initiation in response to osmotic stress|up-regulation of translation initiation in response to osmotic stress|activation of translation initiation in response to osmotic stress|up regulation of translation initiation in response to osmotic stress Any process that activates or increases the frequency, rate or extent of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. GO:0007099 centriole replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007099 ciliary basal body duplication|centriole duplication|microtubule basal body duplication The cell cycle process in which a daughter centriole is formed perpendicular to an existing centriole. An immature centriole contains a ninefold radially symmetric array of single microtubules; mature centrioles consist of a radial array of nine microtubule triplets, doublets, or singlets depending upon the species and cell type. Duplicated centrioles also become the ciliary basal body in cells that form cilia during G0. GO:0007098 centrosome cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007098 centrosome organization and biogenesis|centrosome organisation|centrosome organization The cell cycle process in which centrosome duplication and separation takes place. The centrosome cycle can operate with a considerable degree of independence from other processes of the cell cycle. GO:0007097 nuclear migration biolink:BiologicalProcess go-plus goslim_aspergillus http://purl.obolibrary.org/obo/GO_0007097 positioning of nucleus|establishment of localization of nucleus|nucleus positioning|nuclear movement|establishment of nucleus localisation|establishment of nucleus localization|establishment of position of nucleus|nucleus migration|establishment of cell nucleus localization|nuclear positioning The directed movement of the nucleus to a specific location within a cell. GO:0032052 bile acid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032052 Interacting selectively and non-covalently with bile acids, any of a group of steroid carboxylic acids occurring in bile. GO:0032051 clathrin light chain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032051 Interacting selectively and non-covalently with a clathrin light chain. GO:0032050 clathrin heavy chain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032050 Interacting selectively and non-covalently with a clathrin heavy chain. CHEBI:3962 curcumin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_3962 CHEBI:60721 all-trans-decaprenyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60721 CHEBI:60724 dipalmitoyl phosphatidylglycerol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60724 GO:0032059 bleb biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0032059 Wikipedia:Bleb_(cell_biology) plasma membrane bleb A cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Blebs are formed during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses. GO:0032058 positive regulation of translational initiation in response to stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032058 up regulation of translation initiation in response to stress|upregulation of translation initiation in response to stress|stimulation of translation initiation in response to stress|up-regulation of translation initiation in response to stress|activation of translation initiation in response to stress Any process that activates or increases the frequency, rate or extent of translation initiation as a result of a stimulus indicating the organism is under stress. GO:0032057 negative regulation of translational initiation in response to stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032057 down-regulation of translation initiation in response to stress|downregulation of translation initiation in response to stress|down regulation of translation initiation in response to stress|inhibition of translation initiation in response to stress Any process that stops, prevents or reduces the rate of translation initiation as a result of a stimulus indicating the organism is under stress. GO:0032056 positive regulation of translation in response to stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032056 upregulation of translation in response to stress|up regulation of translation in response to stress|activation of translation in response to stress|stimulation of translation in response to stress|up-regulation of translation in response to stress Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress. GO:0032055 negative regulation of translation in response to stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032055 down regulation of translation in response to stress|downregulation of translation in response to stress|down-regulation of translation in response to stress|inhibition of translation in response to stress Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating the organism is under stress. GO:0032054 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032054 GO:0032053 ciliary basal body organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032053 microtubule basal body organisation|microtubule basal body organization|microtubule basal body organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ciliary basal body, a short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum). GO:0032041 NAD-dependent histone deacetylase activity (H3-K14 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032041 EC:3.5.1.98 Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 14) + H2O = histone H3 L-lysine (position 14) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 14 of the histone H3 protein. GO:0032040 small-subunit processome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032040 small subunit processome|SSU processome A large ribonucleoprotein complex that is an early preribosomal complex. In S. cerevisiae, it has a size of 80S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins. CHEBI:60732 guanosine 3'-monophosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60732 CHEBI:3978 cyanin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_3978 GO:0032049 cardiolipin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032049 MetaCyc:PWY-5269 diphosphatidylglycerol biosynthesis|diphosphatidylglycerol biosynthetic process The chemical reactions and pathways resulting in the formation of cardiolipin, 1,3-bis(3-phosphatidyl)glycerol. GO:0032048 cardiolipin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032048 diphosphatidylglycerol metabolic process|diphosphatidylglycerol metabolism|cardiolipin metabolism The chemical reactions and pathways involving cardiolipin, 1,3-bis(3-phosphatidyl)glycerol. GO:0032047 mitosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032047 Wikipedia:Mitosome crypton A double-membrane-bounded organelle that functions in iron-sulfur protein maturation; evolutionarily derived from mitochondria. The mitosome has been detected only in anaerobic or microaerophilic organisms that do not have mitochondria, such as Entamoeba histolytica, Giardia intestinalis and several species of Microsporidia. These organisms are not capable of gaining energy from oxidative phosphorylation, which is normally performed by mitochondria. GO:0032046 micropexophagy-specific membrane apparatus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032046 MIPA|micropexophagic apparatus A membrane-bounded flattened sac that is formed during micropexophagy between the membrane tips of an engulfing vacuole, completing the engulfment and sequestration of peroxisomes from the cytosol, and forming a micropexophagic body within the lumen of the vacuole. GO:0032045 guanyl-nucleotide exchange factor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032045 A protein complex that stimulates the exchange of guanyl nucleotides associated with a GTPase. GO:0032044 DSIF complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032044 Spt5-Spt4 complex|Spt4-Spt5 complex|DRB sensitivity inducing factor complex|5,6-Dichloro-1-beta-D-ribofuranosylbenzimidazole sensitivity inducing factor complex A heterodimeric protein complex formed of Spt4 and Spt5 proteins which is expressed in eukaryotes from yeast to man. DSIF is an inhibitory elongation factor that promotes RNA polymerase II transcriptional pausing, but can also stimulate transcriptional elongation under certain conditions, and may play a role in RNA processing via its physical association with mRNA capping enzymes. GO:0032043 mitochondrial DNA catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032043 mitochondrial DNA catabolism|mtDNA catabolic process|mitochondrial DNA degradation|mitochondrial DNA breakdown|mtDNA catabolism|mtDNA degradation|mtDNA breakdown The chemical reactions and pathways resulting in the breakdown of mitochondrial DNA. GO:0032042 mitochondrial DNA metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032042 mitochondrial DNA metabolism|mtDNA metabolism|mtDNA metabolic process The chemical reactions and pathways involving mitochondrial DNA. GO:1900518 regulation of response to pullulan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900518 Any process that modulates the frequency, rate or extent of response to pullulan. GO:0046682 response to cyclodiene biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046682 cyclodiene susceptibility/resistance|cyclodiene resistance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclodiene stimulus. A cyclodiene is any organic insecticide (as dieldrin or chlordane) with a chlorinated methylene group forming a bridge across a 6-membered carbon ring. GO:1900517 positive regulation of xylose catabolic process to ethanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900517 positive regulation of xylose catabolism to ethanol|upregulation of xylose catabolic process to ethanol|up regulation of xylose catabolism to ethanol|up regulation of xylose catabolic process to ethanol|upregulation of xylose catabolism to ethanol|activation of xylose catabolic process to ethanol|up-regulation of xylose catabolism to ethanol|up-regulation of xylose catabolic process to ethanol|activation of xylose catabolism to ethanol Any process that activates or increases the frequency, rate or extent of xylose catabolic process to ethanol. GO:0046681 response to carbamate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046681 carbamate resistance|carbamate susceptibility/resistance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbamate stimulus. Carbamates are a group of insecticides and parasiticides that act by inhibiting cholinesterase. GO:0046680 response to DDT biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046680 DDT susceptibility/resistance|DDT resistance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a DDT stimulus. DDT, dichlorodiphenyltrichloroethane, is a chlorinated hydrocarbon pesticide moderately toxic to humans and other animals. GO:1900519 negative regulation of response to pullulan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900519 down regulation of response to pullulan|inhibition of response to pullulan|down-regulation of response to pullulan|downregulation of response to pullulan Any process that stops, prevents or reduces the frequency, rate or extent of response to pullulan. GO:1900514 positive regulation of starch utilization system complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900514 up regulation of SUS complex assembly|positive regulation of assembly of starch utilization system complex|up regulation of starch utilization system complex assembly|activation of assembly of starch utilization system complex|upregulation of SUS complex assembly|up-regulation of assembly of starch utilization system complex|upregulation of starch utilization system complex assembly|up-regulation of SUS complex assembly|upregulation of assembly of starch utilization system complex|up-regulation of starch utilization system complex assembly|activation of SUS complex assembly|activation of starch utilization system complex assembly|positive regulation of SUS complex assembly|up regulation of assembly of starch utilization system complex Any process that activates or increases the frequency, rate or extent of starch utilization system complex assembly. GO:1900513 negative regulation of starch utilization system complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900513 down-regulation of starch utilization system complex assembly|downregulation of SUS complex assembly|negative regulation of assembly of starch utilization system complex|down-regulation of assembly of starch utilization system complex|down regulation of SUS complex assembly|downregulation of starch utilization system complex assembly|down regulation of starch utilization system complex assembly|inhibition of SUS complex assembly|inhibition of starch utilization system complex assembly|inhibition of assembly of starch utilization system complex|down regulation of assembly of starch utilization system complex|negative regulation of SUS complex assembly|down-regulation of SUS complex assembly|downregulation of assembly of starch utilization system complex Any process that stops, prevents or reduces the frequency, rate or extent of starch utilization system complex assembly. GO:1900516 negative regulation of xylose catabolic process to ethanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900516 downregulation of xylose catabolism to ethanol|down regulation of xylose catabolic process to ethanol|downregulation of xylose catabolic process to ethanol|down regulation of xylose catabolism to ethanol|inhibition of xylose catabolism to ethanol|down-regulation of xylose catabolic process to ethanol|inhibition of xylose catabolic process to ethanol|down-regulation of xylose catabolism to ethanol|negative regulation of xylose catabolism to ethanol Any process that stops, prevents or reduces the frequency, rate or extent of xylose catabolic process to ethanol. GO:1900515 regulation of xylose catabolic process to ethanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900515 regulation of xylose catabolism to ethanol Any process that modulates the frequency, rate or extent of xylose catabolic process to ethanol. GO:1900510 negative regulation of pentose catabolic process to ethanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900510 down-regulation of pentose catabolic process to ethanol|negative regulation of pentose catabolism to ethanol|down-regulation of pentose catabolism to ethanol|downregulation of pentose catabolic process to ethanol|down regulation of pentose catabolic process to ethanol|inhibition of pentose catabolic process to ethanol|inhibition of pentose catabolism to ethanol|down regulation of pentose catabolism to ethanol|downregulation of pentose catabolism to ethanol Any process that stops, prevents or reduces the frequency, rate or extent of pentose catabolic process to ethanol. CL:2000034 anterior lateral line neuromast hair cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000034 Any neuromast hair cell that is part of a anterior lateral line. GO:0046689 response to mercury ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046689 response to mercuric ion|response to mercury|mercuric sensitivity/resistance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercury ion stimulus. CL:2000033 limb basal cell of epidermis biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000033 Any basal cell of epidermis that is part of a limb. GO:0046688 response to copper ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046688 response to copper|copper sensitivity/resistance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus. GO:1900512 regulation of starch utilization system complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900512 regulation of SUS complex assembly|regulation of assembly of starch utilization system complex Any process that modulates the frequency, rate or extent of starch utilization system complex assembly. UBERON:2000120 lateral line ganglion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_2000120 lateral line ganglia|LLG Ganglion that develops from a cranial ectodermal placode and contains sensory neurons that innervate a lateral line. CL:2000036 anterior lateral line neuromast support cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000036 Any neuromast support cell that is part of a anterior lateral line. GO:1900511 positive regulation of pentose catabolic process to ethanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900511 up regulation of pentose catabolism to ethanol|positive regulation of pentose catabolism to ethanol|activation of pentose catabolism to ethanol|up regulation of pentose catabolic process to ethanol|up-regulation of pentose catabolism to ethanol|upregulation of pentose catabolic process to ethanol|upregulation of pentose catabolism to ethanol|up-regulation of pentose catabolic process to ethanol|activation of pentose catabolic process to ethanol Any process that activates or increases the frequency, rate or extent of pentose catabolic process to ethanol. CL:2000035 anterior lateral line neuromast mantle cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000035 Any neuromast mantle cell that is part of a anterior lateral line. GO:0046687 response to chromate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046687 chromate sensitivity/resistance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chromate stimulus. CL:2000030 hypothalamus cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000030 Any native cell that is part of a hypothalamus. GO:0046686 response to cadmium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046686 response to cadmium|cadmium sensitivity/resistance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus. GO:0046685 response to arsenic-containing substance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046685 response to arsenic|arsenate sensitivity/resistance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides. GO:0046684 response to pyrethroid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046684 pyrethroid susceptibility/resistance|pyrethroid resistance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pyrethroid stimulus. Pyrethroids are a group of growth regulators, analogous to insect juvenile hormones, that interfere with the development of insect larvae and are used in the control of insects that are harmful in the adult stage. CL:2000032 peripheral nervous system neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000032 Any neuron that is part of a peripheral nervous system. CL:2000031 lateral line ganglion neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000031 Any neuron that is part of a lateral line ganglion. GO:0046683 response to organophosphorus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046683 organophosphorus susceptibility/resistance|organophosphorus resistance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organophosphorus stimulus. Organophosphorus is a compound containing phosphorus bound to an organic molecule; several organophosphorus compounds are used as insecticides, and they are highly toxic cholinesterase inhibitors. UBERON:0002360 meninx biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002360 meningeal layer|layer of meninges|meninx primitiva Membrane organ that surrounds the brain and the spinal cord. CHEBI:59740 nucleophilic reagent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59740 UBERON:0002362 arachnoid mater biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002362 arachnoid mater of neuraxis|arachnoidea mater|arachnoid|arachnoid membrane A think avascular meningeal layer, between the pia mater and the dural mater. It is separated from the pia mater by the subarachnoid space. UBERON:0002361 pia mater biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002361 pia mater of neuraxis|pial membrane|pia The innermost layer of the leptomeninges, consisting of a delicate membrane closely covering the surface of the brain and spinal cord,and lying under the arachnoid membrane. The pia, unlike the arachnoid, extends into the sulci in gyrencephalic animals. CHEBI:35774 CDP-glycerols biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35774 CL:2000038 posterior lateral line neuromast mantle cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000038 Any neuromast mantle cell that is part of a posterior lateral line. CHEBI:35776 arsenic oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35776 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071649 regulation of Regulated upon Activation, Normal T-cell Expressed, and Secreted production|regulation of CCL5 production|regulation of RANTES production Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5. CL:2000037 posterior lateral line neuromast hair cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000037 Any neuromast hair cell that is part of a posterior lateral line. GO:0071648 positive regulation of macrophage inflammatory protein-1 gamma production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071648 positive regulation of MIP-1g production|positive regulation of chemokine (C-C motif) ligand 9 production|positive regulation of CCL9 production Any process that activates or increases the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma. CHEBI:35779 dicarboxylic acid diamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35779 GO:0071647 negative regulation of macrophage inflammatory protein-1 gamma production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071647 negative regulation of CCL9 production|negative regulation of MIP-1g production|negative regulation of chemokine (C-C motif) ligand 9 production Any process that stops, prevents, or reduces the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma. CL:2000039 posterior lateral line neuromast support cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000039 Any neuromast support cell that is part of a posterior lateral line. GO:0071646 regulation of macrophage inflammatory protein-1 gamma production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071646 regulation of chemokine (C-C motif) ligand 9 production|regulation of CCL9 production|regulation of MIP-1g production Any process that modulates the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma. UBERON:0002368 endocrine gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002368 glandulae endocrinae|glandula endocrina|ductless gland|ductless gland Endocrine glands are glands of the endocrine system that secrete their products directly into the circulatory system rather than through a duct.[WP, modified]. UBERON:0002367 prostate gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002367 prostata|male prostate|prostate The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid. GO:0071645 positive regulation of chemokine (C-C motif) ligand 4 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071645 positive regulation of CCL4 production|positive regulation of MIP-1b production|positive regulation of macrophage inflammatory protein production Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4. GO:0071644 negative regulation of chemokine (C-C motif) ligand 4 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071644 negative regulation of macrophage inflammatory protein production|negative regulation of CCL4 production|negative regulation of MIP-1b production Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4. GO:0071643 regulation of chemokine (C-C motif) ligand 4 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071643 regulation of macrophage inflammatory protein production|regulation of CCL4 production|regulation of MIP-1b production Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4. UBERON:0002369 adrenal gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002369 adrenal|glandula suprarenalis|interrenal gland|suprarenal gland|glandula suprarenalis|suprarenal capsule|epinephric gland|adrenal capsule|atrabiliary capsule|glandula adrenalis|epinephros|adrenal medulla cell Either of a pair of complex endocrine organs near the anterior medial border of the kidney consisting of a mesodermal cortex that produces glucocorticoid, mineralocorticoid, and androgenic hormones and an ectodermal medulla that produces epinephrine and norepinephrine[BTO]. UBERON:0002364 tympanic membrane biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002364 eardrum|ear drum|membranous wall of tympanic cavity|Rivinus' membrane|myrinx|paries membranaceus cavi tympani|lateral wall of tympanic cavity|tympanum A thin membrane that separates the external ear from the middle ear, consisting of two epithelia (one part of the the external accoustic meatus epithelium, the other part of the tympanic cavity epithelium) with a fibrous layer between them. Its function is to transmit sound from the air to the ossicles inside the middle ear. The malleus bone bridges the gap between the eardrum and the other ossicles. Rupture or perforation of the eardrum can lead to conductive hearing loss. [WP,unvetted]. GO:0071642 positive regulation of macrophage inflammatory protein 1 alpha production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071642 positive regulation of chemokine (C-C motif) ligand 3 production|positive regulation of CCL3 production|positive regulation of MIP-1a production|positive regulation of macrophage inflammatory protein production Any process that activates or increases the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha. UBERON:0002363 dura mater biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002363 pachymeninges|dura|dura mater of neuraxis Thick, fibrous meningeal covering surrounding the brain and spinal cord. It is the outermost of the three meningeal coverings. It consists of two layers: the periosteal dura linking the inner surface of the skull and the meningeal dura that lies above the arachnoid dural membrane. The meningeal layer draws away from the periosteal layer and certain locations to form the dural reflections. GO:0071641 negative regulation of macrophage inflammatory protein 1 alpha production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071641 negative regulation of chemokine (C-C motif) ligand 3 production|negative regulation of macrophage inflammatory protein production|negative regulation of CCL3 production|negative regulation of MIP-1a production Any process that stops, prevents, or reduces the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha. GO:0071640 regulation of macrophage inflammatory protein 1 alpha production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071640 regulation of macrophage inflammatory protein production|regulation of chemokine (C-C motif) ligand 3 production|regulation of CCL3 production|regulation of MIP-1a production Any process that modulates the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha. CHEBI:35771 glycerophosphoinositol phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35771 UBERON:0002365 exocrine gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002365 glandula exocrina|ducted gland A gland that secretes products (excluding hormones and other chemical messengers) into ducts (duct glands) which lead directly into the external environment[WP]. Typical exocrine glands include sweat glands, salivary glands, mammary glands, stomach, liver, pancreas GO:1900529 obsolete regulation of cell shape involved in cellular response to glucose starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900529 regulation of cell shape involved in cellular response to glucose starvation OBSOLETE. Any regulation of cell shape that is involved in cellular response to glucose starvation. GO:0046693 sperm storage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046693 sequestration of sperm|sperm sequestering|sperm retention|storage of sperm|retention of sperm|sperm sequestration|sequestering of sperm The retention of sperm by a female following mating. GO:1900528 obsolete regulation of cell shape involved in G1 to G0 transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900528 regulation of cell shape involved in establishment of cell quiescence|regulation of cell shape involved in cell cycle quiescence|regulation of cell shape involved in G1 to G0 transition|regulation of cell shape involved in stationary phase|regulation of cell shape involved in G1/G0 transition OBSOLETE. Any regulation of cell shape that is involved in G1 to G0 transition. GO:0046692 sperm competition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046692 Wikipedia:Sperm_competition Any process that contributes to the success of sperm fertilization in multiply-mated females. GO:0046691 intracellular canaliculus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0046691 canalicular membrane An apical plasma membrane part that forms a narrow enfolded luminal membrane channel, lined with numerous microvilli, that appears to extend into the cytoplasm of the cell. A specialized network of intracellular canaliculi is a characteristic feature of parietal cells of the gastric mucosa in vertebrates. GO:0046690 response to tellurium ion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046690 tellurium sensitivity/resistance|response to tellurium Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tellurium ion stimulus. GO:1900525 obsolete positive regulation of phosphatidylserine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900525 positive regulation of phosphatidylserine synthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of phosphatidylserine synthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of phosphatidylserine formation by positive regulation of transcription from RNA polymerase II promoter|up regulation of phosphatidylserine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of phosphatidylserine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up regulation of phosphatidylserine formation by positive regulation of transcription from RNA polymerase II promoter|activation of phosphatidylserine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|positive regulation of phosphatidylserine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|upregulation of phosphatidylserine anabolism by positive regulation of transcription from RNA polymerase II promoter|activation of phosphatidylserine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|upregulation of phosphatidylserine synthesis by positive regulation of transcription from RNA polymerase II promoter|upregulation of phosphatidylserine formation by positive regulation of transcription from RNA polymerase II promoter|up-regulation of phosphatidylserine anabolism by positive regulation of transcription from RNA polymerase II promoter|up-regulation of phosphatidylserine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up-regulation of phosphatidylserine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of phosphatidylserine synthesis by positive regulation of transcription from RNA polymerase II promoter|activation of phosphatidylserine anabolism by positive regulation of transcription from RNA polymerase II promoter|up-regulation of phosphatidylserine formation by positive regulation of transcription from RNA polymerase II promoter|upregulation of phosphatidylserine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|upregulation of phosphatidylserine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|activation of phosphatidylserine synthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of phosphatidylserine anabolism by positive regulation of transcription from RNA polymerase II promoter|activation of phosphatidylserine formation by positive regulation of transcription from RNA polymerase II promoter|up regulation of phosphatidylserine anabolism by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that activates or increases the frequency, rate or extent of phosphatidylserine biosynthetic process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:1900524 obsolete positive regulation of flocculation via cell wall protein-carbohydrate interaction by positive regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900524 up-regulation of flocculation via cell wall protein-carbohydrate interaction by positive regulation of transcription from RNA polymerase II promoter|upregulation of flocculation via cell wall protein-carbohydrate interaction by positive regulation of transcription from RNA polymerase II promoter|up regulation of flocculation via cell wall protein-carbohydrate interaction by positive regulation of transcription from RNA polymerase II promoter|activation of flocculation via cell wall protein-carbohydrate interaction by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that activates or increases the frequency, rate or extent of flocculation via cell wall protein-carbohydrate interaction process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter. UBERON:0002349 myocardium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002349 cardiac muscle|muscle of heart|heart myocardium|heart muscle the middle layer of the heart, comprised mainly of striated cardiac muscle fibers GO:1900527 obsolete regulation of nucleus size involved in G1 to G0 transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900527 regulation of nucleus size involved in cell cycle quiescence|regulation of nuclear size involved in establishment of cell quiescence|regulation of nucleus size involved in stationary phase|regulation of nucleus size involved in G1 to G0 transition|regulation of nuclear size involved in G1 to G0 transition|regulation of nucleus size involved in G1/G0 transition|regulation of nuclear volume involved in stationary phase|regulation of nuclear volume involved in G1 to G0 transition|regulation of nuclear volume involved in G1/G0 transition|regulation of nuclear size involved in stationary phase|regulation of nuclear size involved in G1/G0 transition|regulation of nucleus size involved in establishment of cell quiescence|regulation of nuclear size involved in cell cycle quiescence|regulation of nuclear volume involved in establishment of cell quiescence|regulation of nuclear volume involved in cell cycle quiescence OBSOLETE. Any regulation of nucleus size that is involved in G1 to G0 transition. CHEBI:59739 electrophilic reagent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59739 GO:1900526 obsolete negative regulation of phosphatidylserine biosynthetic process by negative regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900526 negative regulation of phosphatidylserine synthesis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of phosphatidylserine formation by negative regulation of transcription from RNA polymerase II promoter|negative regulation of phosphatidylserine biosynthesis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of phosphatidylserine anabolism by negative regulation of transcription from RNA polymerase II promoter OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of phosphatidylserine biosynthetic process by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter. GO:1900521 regulation of response to amylopectin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900521 Any process that modulates the frequency, rate or extent of response to amylopectin. PR:000021385 secretin proteolytic cleavage product biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000021385 SCT/ClvPrd A secretin that has been processed by proteolytic cleavage. GO:1900520 positive regulation of response to pullulan biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900520 up regulation of response to pullulan|upregulation of response to pullulan|activation of response to pullulan|up-regulation of response to pullulan Any process that activates or increases the frequency, rate or extent of response to pullulan. CL:2000022 cardiac septum cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000022 Any native cell that is part of a cardiac septum. GO:1900523 positive regulation of response to amylopectin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900523 upregulation of response to amylopectin|up regulation of response to amylopectin|activation of response to amylopectin|up-regulation of response to amylopectin Any process that activates or increases the frequency, rate or extent of response to amylopectin. GO:0046699 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046699 CL:2000025 spinal cord oligodendrocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000025 Any oligodendrocyte that is part of a spinal cord. GO:0046698 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046698 GO:1900522 negative regulation of response to amylopectin biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900522 down regulation of response to amylopectin|downregulation of response to amylopectin|down-regulation of response to amylopectin|inhibition of response to amylopectin Any process that stops, prevents or reduces the frequency, rate or extent of response to amylopectin. GO:0046697 decidualization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046697 Wikipedia:Decidualization decidual cell reaction The cellular and vascular changes occurring in the endometrium of the pregnant uterus just after the onset of blastocyst implantation. This process involves the proliferation and differentiation of the fibroblast-like endometrial stromal cells into large, polyploid decidual cells that eventually form the maternal component of the placenta. GO:0046696 lipopolysaccharide receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0046696 LPS receptor complex A multiprotein complex that consists of at least three proteins, CD14, TLR4, and MD-2, each of which is glycosylated and which functions as a lipopolysaccharide (LPS) receptor that primes the innate immune response against bacterial pathogens. CL:2000021 sebaceous gland cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000021 Any native cell that is part of a sebaceous gland. GO:0046695 SLIK (SAGA-like) complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0046695 SLIK/SALSA complex|SAGA (alt) complex|SALSA complex A SAGA-type histone acetyltransferase complex that contains Rtg2 and a smaller form of Spt7 than the fungal SAGA complex, and lacks Spt8. The complex is involved in the yeast retrograde response pathway, which is important for gene expression changes during mitochondrial dysfunction. CL:2000020 inner cell mass cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000020 Any native cell that is part of a inner cell mass. GO:0046694 sperm incapacitation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046694 The process in which the use of stored sperm from the first-mating male is inhibited by the seminal fluid of subsequently mating males. CHEBI:35783 bornane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35783 UBERON:0002351 sinoatrial node biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002351 node of Keith-Flack|Koch's node|cardiac pacemaker|sinus node|sinus node of Keith and Flack|sinu-atrial node|nodus sinuatrialis|sinoatrial node|nodus sinuatrialis|SA node|sinuatrial nodal muscle tissue|sinuatrial node|SA nodal muscle tissue The part of the cardiac conduction system that controls the timing of heart muscle contraction. It relays electrical signals to the AV node[GO]. Subdivision of conducting system of heart at the junction of the right atrium and the superior vena cava, around the sinoatrial nodal branch of right coronary artery and is continuous with the internodal tract[FMA]. CHEBI:35786 phosphosphingolipid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35786 UBERON:0002350 conducting system of heart biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002350 cardiac conducting system|impulse conducting system|cardiac conduction system|cardiac impulse conducting system|cardionector|central conduction system|heart conduction system|complexus stimulans cordis|systema conducente cordis The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat[GO] CHEBI:35785 sphingoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35785 GO:0071639 positive regulation of monocyte chemotactic protein-1 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071639 positive regulation of CCL2 production|positive regulation of MCP-1 production Any process that activates or increases the frequency, rate, or extent of production of monocyte chemotactic protein-1. CHEBI:35788 seco-steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35788 GO:0071638 negative regulation of monocyte chemotactic protein-1 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071638 negative regulation of MCP-1 production|negative regulation of CCL2 production Any process that stops, prevents, or reduces the frequency, rate, or extent of production of monocyte chemotactic protein-1. GO:0071637 regulation of monocyte chemotactic protein-1 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071637 regulation of CCL2 production|regulation of MCP-1 production Any process that modulates the frequency, rate, or extent of production of monocyte chemotactic protein-1. CL:2000029 central nervous system neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000029 Any neuron that is part of a central nervous system. GO:0071636 positive regulation of transforming growth factor beta production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071636 positive regulation of TGFbeta production|positive regulation of TGF-beta production|positive regulation of TGFB production|positive regulation of TGF-B production|positive regulation of transforming growth factor-beta production|positive regulation of transforming growth factor-beta secretion Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta. CHEBI:35789 oxo steroid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35789 CL:2000028 cerebellum glutamatergic neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000028 Any glutamatergic neuron that is part of a cerebellum. UBERON:0002357 serous pericardium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002357 serous portion of pericardium|pericardium serosum Serous membrane which is divided into parietal and visceral serous pericardium. GO:0071635 negative regulation of transforming growth factor beta production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071635 negative regulation of TGFbeta production|negative regulation of TGF-beta production|negative regulation of TGF-B production|negative regulation of TGFB production|negative regulation of transforming growth factor-beta production|negative regulation of transforming growth factor-beta secretion Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta. CHEBI:59737 nucleotide-sugar oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59737 GO:0071634 regulation of transforming growth factor beta production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071634 regulation of transforming growth factor-beta production|regulation of TGF-beta production|regulation of TGFB production|regulation of TGFbeta production|regulation of transforming growth factor-beta secretion|regulation of TGF-B production Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta. UBERON:0002359 fibrous pericardium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002359 pericardium fibrosum|fibrous portion of pericardium Membrane organ which is attached to the pericardial sac proper and the central tendon of diaphragm and is continuous with the pretracheal fascia.[FMA] GO:0071633 dihydroceramidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071633 Catalysis of the reaction: a dihydroceramide + H2O = a fatty acid + dihydrosphingosine. UBERON:0002358 peritoneum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002358 peritonaeum A serous membrane that lines the peritoneal cavity[VHOG,modified]. GO:0071632 optomotor response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071632 Wikipedia:Optomotor_response Eye, head or whole body movements that help to compensate movements of the environment in order to stabilize its image on the retina. In the case of whole body movements, these motor actions may also stabilize a locomotor course in response to some disturbance. Examples include: the optokinetic reflex, which allows human eyes to follow objects in motion while the head remains stationary reflex; the optomotor responses of flying insects and swimming fish. UBERON:0002353 atrioventricular bundle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002353 AV bundle|fasciculus atrioventricularis|bundle of His|atrio-ventricular bundle|atrioventricular fasciculus|atrioventricular bundle muscle tissue|A-V bundle|His bundle A part of the His-Purkinje system that transmits signals from the AV node to the cardiac Purkinje fibers[GO] GO:0071631 mating pheromone secretion involved in positive regulation of conjugation with cellular fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071631 mating-type pheromone secretion involved in conjugation with cellular fusion The regulated release of a mating pheromone, a peptide hormone that induces a behavioral or physiological response(s) from a responding organism or cell, that positively regulates a conjugation process that results in the union of cellular and genetic information from compatible mating types. CHEBI:11791 3-deoxy-D-manno-octulosonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_11791 CHEBI:35780 phosphate ion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35780 GO:0071630 nuclear protein quality control by the ubiquitin-proteasome system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071630 nucleus-associated proteasomal ubiquitin-dependent protein breakdown|nucleus-associated proteasomal ubiquitin-dependent protein catabolism|nucleus-associated proteasomal ubiquitin-dependent protein degradation|ubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome The chemical reactions and pathways resulting in the breakdown of misfolded proteins via a mechanism in which the proteins are transported to the nucleus for ubiquitination, and then targeted to proteasomes for degradation. UBERON:0002352 atrioventricular node biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002352 downstream pacemaker|AV node|atriovetricular node|Aschoff-Tawara node|atrio-ventricular node|nodus atrioventricularis|nodus atrioventricularis|atrioventricular nodal muscle tissue|AV nodal muscle tissue|A-V node|node of Tawara An area of conducting tissue between the atria and the ventricles of the heart that conducts the normal electrical impulse from the atria to the ventricles. CHEBI:35782 diphosphate ion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35782 UBERON:0002355 pelvic region of trunk biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002355 pelvis region|pelvis|lesser pelvis|true pelvis|pelvic region The lower segment of the trunk, inferioposterior to the abdomen proper, in the transition area between the trunk and the lower limbs. UBERON:0002354 cardiac Purkinje fiber biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002354 cardiac Purkinje fiber|Purkinje fiber|heart Purkinje fiber|myofibra conducens cardiacus|subendocardial branch The cardiac Purkinje fiber is part of the cardiac conduction system that receives signals from the bundle of His and innervates the ventricular cardiac muscle GO:0071660 positive regulation of IP-10 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071660 positive regulation of CXCL10 production|positive regulation of chemokine (C-C motif) ligand 10 production Any process that activates or increases the frequency, rate, or extent of production of IP-10. GO:1900539 fumonisin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900539 fumonisin metabolism The chemical reactions and pathways involving fumonisin. UBERON:0002339 epithelium of lobar bronchus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002339 epithelial tissue of lobar bronchus|epithelial tissue of secondary bronchus|epithelium of secondary bronchus|lobar bronchus epithelial tissue|secondary bronchus epithelium|secondary bronchus epithelial tissue|lobar bronchus epithelium|lobar bronchial epithelium The tissue made up of epithelial cells that lines the inside of the lobar bronchus. GO:1900536 obsolete regulation of glucose homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900536 regulation of glucose homeostasis OBSOLETE. Any process that modulates the frequency, rate or extent of glucose homeostasis. UBERON:0002338 lamina propria of bronchus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002338 lamina propria mucosa of bronchi|lamina propria mucosa of bronchial trunk|lamina propria mucosa of bronchus|bronchi lamina propria mucosa|bronchial trunk lamina propria mucosa|bronchus lamina propria mucosa|lamina propria mucosae of bronchus|bronchial lamina propria|lamina propria of bronchi|lamina propria of bronchial trunk|lamina propria mucosae of bronchi|lamina propria mucosae of bronchial trunk|bronchus lamina propria mucosae|bronchial trunk lamina propria mucosae|bronchi lamina propria mucosae|bronchus lamina propria|bronchial trunk lamina propria|bronchi lamina propria A lamina propria that is part of a bronchus [Automatically generated definition]. GO:1900535 palmitic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900535 The chemical reactions and pathways resulting in the formation of palmitic acid. GO:1900538 obsolete positive regulation of glucose homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900538 up-regulation of glucose homeostasis|positive regulation of glucose homeostasis|upregulation of glucose homeostasis|up regulation of glucose homeostasis|activation of glucose homeostasis OBSOLETE. Any process that activates or increases the frequency, rate or extent of glucose homeostasis. GO:1900537 obsolete negative regulation of glucose homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900537 inhibition of glucose homeostasis|negative regulation of glucose homeostasis|down regulation of glucose homeostasis|downregulation of glucose homeostasis|down-regulation of glucose homeostasis OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of glucose homeostasis. CHEBI:35759 1-monoglyceride biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35759 GO:1900532 obsolete negative regulation of cell proliferation involved in cellular hyperosmotic response biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900532 down regulation of cell proliferation of cellular response to hypertonicity|inhibition of cell proliferation of cellular response to hypertonicity|down regulation of cell proliferation of cellular hyperosmotic response|inhibition of cell proliferation of cellular hyperosmotic response|downregulation of cell proliferation of cellular hypertonic response|negative regulation of cell proliferation involved in cellular hyperosmotic response|down regulation of cell proliferation of cellular hypertonic response|inhibition of cell proliferation of cellular hypertonic response|down regulation of cell proliferation of cellular HOG response|downregulation of cell proliferation of cellular HOG response|negative regulation of cell proliferation of cellular response to hypertonicity|down-regulation of cell proliferation of cellular response to hypertonicity|negative regulation of cell proliferation of cellular hyperosmotic response|down-regulation of cell proliferation of cellular hyperosmotic response|negative regulation of cell proliferation of cellular HOG response|down-regulation of cell proliferation of cellular HOG response|down-regulation of cell proliferation of cellular hypertonic response|negative regulation of cell proliferation of cellular hypertonic response|downregulation of cell proliferation of cellular response to hypertonicity|inhibition of cell proliferation of cellular HOG response|downregulation of cell proliferation of cellular hyperosmotic response OBSOLETE. Negative regulation of cell proliferation during cellular hyperosmotic response. CL:2000056 Meynert cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000056 Any pyramidal cell that is part of a regional part of cerebral cortex. GO:1900531 obsolete regulation of cell shape involved in cellular response to heat biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900531 regulation of cell shape involved in cellular response to heat|regulation of cell shape of cellular response to heat|regulation of cell shape of cellular response to heat stress OBSOLETE. Any regulation of cell shape that is involved in cellular response to heat. CL:2000055 liver dendritic cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000055 hepatic dendritic cell Any dendritic cell that is part of a liver. GO:1900534 palmitic acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900534 The chemical reactions and pathways resulting in the breakdown of palmitic acid. GO:1900533 palmitic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900533 The chemical reactions and pathways involving palmitic acid. CL:2000052 umbilical artery endothelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000052 Any endothelial cell of artery that is part of a umbilical cord. CL:2000051 splenic fibroblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000051 Any fibroblast that is part of a spleen. GO:1900530 obsolete regulation of cell shape involved in cellular response to salt stress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900530 regulation of cell shape of cellular response to ionic osmotic stress|regulation of cell shape of cellular response to salt stress|regulation of cell shape of cellular salinity response|regulation of cell shape involved in cellular response to salt stress OBSOLETE. Any regulation of cell shape that is involved in cellular response to salt stress. CL:2000053 splenic endothelial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000053 Any endothelial cell that is part of a spleen. CHEBI:35753 tricarboxylic acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35753 CHEBI:35755 pentacarboxylic acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35755 CHEBI:35754 tetracarboxylic acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35754 CHEBI:35757 monocarboxylic acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35757 GO:0071669 plant-type cell wall organization or biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071669 plant-type cell wall organization and biogenesis|plant-type cell wall organisation or biogenesis A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellulose- and pectin-containing cell wall. UBERON:0002346 neurectoderm biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002346 epithelium tubi neuralis; neuroectoderma|presumptive central nervous system|neuaral ectoderm|neural ectoderm|neuroectoderm|ventral neurogenic region Embryonic ectoderm that gives rise to nervous tissue. GO:0071668 plant-type cell wall assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071668 plant cell wall assembly The aggregation, arrangement and bonding together of a set of components to form a cellulose- and pectin-containing cell wall. GO:0071667 DNA/RNA hybrid binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071667 RNA/DNA hybrid binding Interacting selectively and non-covalently with a RNA/DNA hybrid. UBERON:0002348 epicardium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002348 pericardium visceral mesothelium|visceral serous pericardium proper|heart epicardium|visceral serous pericardium of heart a region of the serous membrane that forms the innermost layer of the pericardium and the outer surface of the heart. GO:0071666 Slit-Robo signaling complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071666 Slit-Robo signalling complex A protein-carbohydrate complex that consists of a transmembrane roundabout (Robo) receptor, an extracellular Slit ligand and heparin/heparan sulfate. CHEBI:59724 ribonucleoside triphosphate oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59724 GO:0071665 gamma-catenin-TCF7L2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071665 plakoglobin-TCF4 complex|gamma-catenin-TCF4 complex A protein complex that contains gamma-catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription. UBERON:0002347 thoracic vertebra biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002347 vertebra of thorax|thorax vertebra|vertebra thoracica|dorsal vertebra A thoracic vertebra endochondral element that is composed primarily of a bone tissue. GO:0071664 catenin-TCF7L2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071664 catenin-TCF4 complex A protein complex that contains a catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription. UBERON:0002342 neural crest biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002342 crista neuralis|NC|neural crest material A specialized region of ectoderm found between the neural ectoderm (neural plate) and non-neural ectoderm and composed of highly migratory pluripotent cells that delaminate in early embryonic development from the dorsal neural tube and give rise to an astounding variety of differentiated cell types[MP]. UBERON:0002341 epithelium of segmental bronchus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002341 segmental bronchus epithelial tissue|segmental bronchus epithelium|epithelium of tertiary bronchus|epithelial tissue of tertiary bronchus|segmental bronchial epithelium|tertiary bronchus epithelial tissue|tertiary bronchus epithelium|epithelial tissue of segmental bronchus An epithelium that is part of a segmental bronchus [Automatically generated definition]. GO:0071663 positive regulation of granzyme B production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071663 Any process that activates or increases the frequency, rate, or extent of production of granzyme B. GO:0071662 negative regulation of granzyme B production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071662 Any process that stops, prevents, or reduces the frequency, rate, or extent of production of granzyme B. CHEBI:59720 HPETE anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59720 GO:0071661 regulation of granzyme B production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071661 Any process that modulates the frequency, rate, or extent of production of granzyme B. UBERON:0002343 abdomen musculature biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002343 muscles of abdomen|musculature of abdomen|abdominal musculature|muscle group of abdomen|set of muscles of abdomen|musculature of abdominal wall Set of all muscles in abdomen. UBERON:0002328 notochord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002328 embryonic notocord|notochorda|notocord A flexible rod-shaped body found in embryos of all chordates. It is composed of cells derived from the mesoderm and defines the primitive axis of the embryo. In some chordates, it persists throughout life as the main axial support of the body, while in most vertebrates it becomes the nucleus pulposus of the intervertebral disc. The notochord is found ventral to the neural tube. GO:1900547 obsolete negative regulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900547 negative regulation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in negative regulation of phenotypic switching. GO:1900546 obsolete positive regulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900546 up regulation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter|up regulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter|activation of phenotypic switching by regulation of transcription from RNA polymerase II promoter|upregulation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter|up-regulation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter|up-regulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter|activation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter|upregulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter|positive regulation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in positive regulation of phenotypic switching. UBERON:0002327 trunk of intercostal nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002327 intercostal neural trunk|intercostal nerve trunk GO:1900549 N',N'',N'''-triacetylfusarinine C metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900549 N',N'',N'''-triacetylfusarinine C metabolism The chemical reactions and pathways involving N',N'',N'''-triacetylfusarinine C. GO:1900548 heme B catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900548 MetaCyc:PWY-5874 protoheme catabolic process|heme B degradation|heme B breakdown|heme B catabolism|protoheme degradation The chemical reactions and pathways resulting in the breakdown of heme b, a Fe(II) porphyrin complex readily isolated from the hemoglobin of beef blood, but also found in other proteins including other hemoglobins, myoglobins, cytochromes P-450, catalases, peroxidases as well as b type cytochromes. UBERON:0002329 somite biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002329 somites|epimere|epimere mesoderm|somitus|somitic mesoderm|mesodermal cluster|epithelial somite Somites are spheres of epithelial cells that form sequentially along the anterior-posterior axis of the embryo through mesenchymal to epithelial transition of the presomitic mesoderm. GO:1900543 negative regulation of purine nucleotide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900543 downregulation of purine metabolism|inhibition of purine metabolic process|down-regulation of purine nucleotide metabolic process|downregulation of purine nucleotide metabolism|negative regulation of purine metabolism|down regulation of purine nucleotide metabolism|down-regulation of purine metabolism|inhibition of purine nucleotide metabolism|inhibition of purine nucleotide metabolic process|negative regulation of purine metabolic process|down-regulation of purine metabolic process|inhibition of purine metabolism|downregulation of purine metabolic process|down regulation of purine nucleotide metabolic process|down regulation of purine metabolic process|downregulation of purine nucleotide metabolic process|negative regulation of purine nucleotide metabolism|down-regulation of purine nucleotide metabolism|down regulation of purine metabolism Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide metabolic process. GO:1900542 regulation of purine nucleotide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900542 regulation of purine nucleotide metabolism|regulation of purine metabolic process|regulation of purine metabolism Any process that modulates the frequency, rate or extent of purine nucleotide metabolic process. GO:1900545 obsolete regulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900545 regulation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of phenotypic switching. CL:2000047 brainstem motor neuron biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000047 Any motor neuron that is part of a brainstem. GO:1900544 positive regulation of purine nucleotide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900544 up regulation of purine nucleotide metabolic process|activation of purine nucleotide metabolic process|positive regulation of purine nucleotide metabolism|up regulation of purine nucleotide metabolism|up regulation of purine metabolism|positive regulation of purine metabolism|up-regulation of purine metabolic process|activation of purine metabolism|up-regulation of purine nucleotide metabolic process|activation of purine metabolic process|upregulation of purine nucleotide metabolism|up-regulation of purine metabolism|positive regulation of purine metabolic process|up regulation of purine metabolic process|upregulation of purine nucleotide metabolic process|activation of purine nucleotide metabolism|up-regulation of purine nucleotide metabolism|upregulation of purine metabolism|upregulation of purine metabolic process Any process that activates or increases the frequency, rate or extent of purine nucleotide metabolic process. CL:2000046 ventricular cardiac muscle cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000046 Any cardiac muscle cell that is part of a cardiac ventricle. GO:1900541 fumonisin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900541 fumonisin anabolism|fumonisin biosynthesis|fumonisin synthesis|fumonisin formation The chemical reactions and pathways resulting in the formation of fumonisin. CL:2000043 brain pericyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000043 Any pericyte cell that is part of a brain. GO:1900540 fumonisin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900540 fumonisin breakdown|fumonisin degradation|fumonisin catabolism The chemical reactions and pathways resulting in the breakdown of fumonisin. CL:2000042 embryonic fibroblast biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000042 Any fibroblast that is part of a embryo. CHEBI:35766 glycerophosphoserine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35766 GO:0071659 negative regulation of IP-10 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071659 negative regulation of CXCL10 production|negative regulation of chemokine (C-C motif) ligand 10 production Any process that stops, prevents, or reduces the frequency, rate, or extent of production of IP-10. GO:0071658 regulation of IP-10 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071658 regulation of chemokine (C-C motif) ligand 10 production|regulation of CXCL10 production Any process that modulates the frequency, rate, or extent of production of IP-10. GO:0071657 positive regulation of granulocyte colony-stimulating factor production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071657 positive regulation of colony stimulating factor 3 (granulocyte) production|positive regulation of lenograstim production|positive regulation of pluripoietin production|positive regulation of granulocyte colony stimulating factor production|positive regulation of filgrastim production|positive regulation of G-CSF production|positive regulation of CSF3 production Any process that activates or increases the frequency, rate, or extent of production of granulocyte colony-stimulating factor. UBERON:0002335 macula densa biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002335 The macula densa is an area of specialized cells in the distal tubule that makes contact with the vascular pole of the glomerulus[GO]. GO:0071656 negative regulation of granulocyte colony-stimulating factor production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071656 negative regulation of CSF3 production|negative regulation of colony stimulating factor 3 (granulocyte) production|negative regulation of lenograstim production|negative regulation of granulocyte colony stimulating factor production|negative regulation of pluripoietin production|negative regulation of filgrastim production|negative regulation of G-CSF production Any process that stops, prevents, or reduces the frequency, rate, or extent of production of granulocyte colony stimulating factor. UBERON:0002334 submandibular duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002334 ductus submandibularis|submandibular salivary duct|Wharton's duct|ductus submaxillaris|submaxillary duct|submaxillar gland duct the duct of the submadibular gland that opens at the sublingual papilla near the frenulum of the tongue GO:0071655 regulation of granulocyte colony-stimulating factor production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071655 regulation of G-CSF production|regulation of pluripoietin production|regulation of filgrastim production|regulation of colony stimulating factor 3 (granulocyte) production|regulation of lenograstim production|regulation of CSF3 production|regulation of granulocyte colony stimulating factor production Any process that modulates the frequency, rate, or extent of production of granulocyte colony-stimulating factor. UBERON:0002337 endometrial stroma biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002337 stroma of endometrium|endometrium stroma The layer of connective tissue comprised of the endometrial lining of the uterus which fluctuates in thickness throughout the menstrual cycle. GO:0071654 positive regulation of chemokine (C-C motif) ligand 1 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071654 positive regulation of TCA-3 production|positive regulation of CCL1 production|positive regulation of T cell activation 3 production Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1. UBERON:0002336 corpus callosum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002336 White matter structure containing massive numbers of commissural fibers connecting cortical areas in the two cerebral hemispheres.it is subdivided into a genu, a rostrum, a body, and a splenium. (MM) UBERON:0002331 umbilical cord biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002331 connecting stalk|yolk stalk|funiculus umbilicalis|funiculus umbilicalis|chorda umbilicalis|birth cord The connecting cord from the developing embryo to the placenta. GO:0071653 negative regulation of chemokine (C-C motif) ligand 1 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071653 negative regulation of T cell activation 3 production|negative regulation of CCL1 production|negative regulation of TCA-3 production Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1. GO:0071652 regulation of chemokine (C-C motif) ligand 1 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071652 regulation of TCA-3 production|regulation of T cell activation 3 production|regulation of CCL1 production Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1. UBERON:0002330 exocrine system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002330 exocrine glandular system Anatomical system that consists of the glands and parts of glands that produce exocrine secretions and help to integrate and control bodily metabolic activity. Exocrine glands are glands that secrete their products (hormones) into ducts (duct glands). They are the counterparts to endocrine glands, which secrete their products (hormones) directly into the bloodstream (ductless glands) or release hormones (paracrines) that affect only target cells nearby the release site. [Wikipedia]. GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071651 positive regulation of CCL5 production|positive regulation of RANTES production|positive regulation of Regulated upon Activation, Normal T-cell Expressed, and Secreted production Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5. UBERON:0002333 pulmonary trunk biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002333 main pulmonary artery|pulmonary artery (trunk)|trunk of pulmonary arterial tree An arterial trunk which is continuous with the heart and branches into the pulmonary arteries. GO:0071650 negative regulation of chemokine (C-C motif) ligand 5 production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071650 negative regulation of Regulated upon Activation, Normal T-cell Expressed, and Secreted production|negative regulation of CCL5 production|negative regulation of RANTES production Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5. GO:0071682 endocytic vesicle lumen biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071682 The volume enclosed by the membrane of an endocytic vesicle. GO:0071681 cellular response to indole-3-methanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071681 cellular response to indole-3-carbinol Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indole-3-methanol stimulus. GO:0071680 response to indole-3-methanol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071680 response to indole-3-carbinol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indole-3-methanol stimulus. GO:1900558 austinol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900558 austinol metabolism The chemical reactions and pathways involving austinol. GO:1900557 emericellamide biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900557 emericellamide biosynthesis|emericellamide anabolism|emericellamide synthesis|emericellamide formation The chemical reactions and pathways resulting in the formation of emericellamide. GO:1900559 austinol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900559 austinol breakdown|austinol catabolism|austinol degradation The chemical reactions and pathways resulting in the breakdown of austinol. CHEBI:35737 monothiocarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35737 GO:1900554 asperfuranone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900554 asperfuranone synthesis|asperfuranone formation|asperfuranone biosynthesis|asperfuranone anabolism The chemical reactions and pathways resulting in the formation of asperfuranone. GO:1900553 asperfuranone catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900553 asperfuranone catabolism|asperfuranone degradation|asperfuranone breakdown The chemical reactions and pathways resulting in the breakdown of asperfuranone. GO:1900556 emericellamide catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900556 emericellamide degradation|emericellamide breakdown|emericellamide catabolism The chemical reactions and pathways resulting in the breakdown of emericellamide. GO:1900555 emericellamide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900555 emericellamide metabolism The chemical reactions and pathways involving emericellamide. GO:1900550 N',N'',N'''-triacetylfusarinine C catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900550 N',N'',N'''-triacetylfusarinine C degradation|N',N'',N'''-triacetylfusarinine C catabolism|N',N'',N'''-triacetylfusarinine C breakdown The chemical reactions and pathways resulting in the breakdown of N',N'',N'''-triacetylfusarinine C. GO:1900552 asperfuranone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900552 asperfuranone metabolism The chemical reactions and pathways involving asperfuranone. GO:1900551 N',N'',N'''-triacetylfusarinine C biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900551 N',N'',N'''-triacetylfusarinine C anabolism|N',N'',N'''-triacetylfusarinine C synthesis|N',N'',N'''-triacetylfusarinine C formation|N',N'',N'''-triacetylfusarinine C biosynthesis The chemical reactions and pathways resulting in the formation of N',N'',N'''-triacetylfusarinine C. CHEBI:35735 dicarboxylic acid monoamide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35735 GO:0071689 muscle thin filament assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071689 The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in striated muscle. GO:0071688 striated muscle myosin thick filament assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071688 The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in striated muscle. GO:0071687 obsolete horsetail nucleus leading edge biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071687 OBSOLETE. The part of the horsetail nucleus where telomeres cluster under the SPB and that leads horsetail movement. The horsetail nucleus is the elongated nucleus which forms during the rapid oscillatory movement at meiotic prophase; characterized in Schizosaccharomyces pombe. GO:0071686 obsolete horsetail nucleus biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071686 OBSOLETE. The elongated nucleus which forms during the rapid oscillatory movement at meiotic prophase; characterized in Schizosaccharomyces pombe. GO:0071685 NADH dehydrogenase complex (plastoquinone) biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071685 An NADH dehydrogenase complex that catalyzes the transfer of electrons to plastoquinone. The complex is involved in the non-photochemical reduction of plastoquinones and the cyclic electron transport around photosystem I, and is found in plastid thylakoids. GO:0071684 organism emergence from protective structure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071684 The developmental process in which an organism emerges from a surrounding protective structure such as an egg or pupa case. GO:0071683 sensory dendrite biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071683 A dendrite that is found on a sensory neuron, and directly transduces a sensory signal from the sensory neuron to another neuron. GO:0071671 regulation of smooth muscle cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071671 Any process that modulates the frequency, rate, or extent of smooth muscle cell chemotaxis. GO:0071670 smooth muscle cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071670 The directed movement of a smooth muscle cell in response to an external stimulus. CHEBI:21101 D-altraric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21101 CHEBI:21100 D-altrarate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21100 GO:1900569 chanoclavine-I aldehyde biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900569 chanoclavine-I aldehyde anabolism|chanoclavine-I aldehyde synthesis|chanoclavine-I aldehyde biosynthesis|chanoclavine-I aldehyde formation The chemical reactions and pathways resulting in the formation of chanoclavine-I aldehyde. GO:1900568 chanoclavine-I aldehyde catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900568 chanoclavine-I aldehyde degradation|chanoclavine-I aldehyde breakdown|chanoclavine-I aldehyde catabolism The chemical reactions and pathways resulting in the breakdown of chanoclavine-I aldehyde. GO:1900565 chanoclavine-I catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900565 chanoclavine-I breakdown|chanoclavine-I catabolism|chanoclavine-I degradation The chemical reactions and pathways resulting in the breakdown of chanoclavine-I. CHEBI:35748 fatty acid ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35748 GO:1900564 chanoclavine-I metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900564 chanoclavine-I metabolism The chemical reactions and pathways involving chanoclavine-I. GO:1900567 chanoclavine-I aldehyde metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900567 chanoclavine-I aldehyde metabolism The chemical reactions and pathways involving chanoclavine-I aldehyde. GO:1900566 chanoclavine-I biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900566 chanoclavine-I anabolism|chanoclavine-I synthesis|chanoclavine-I formation|chanoclavine-I biosynthesis The chemical reactions and pathways resulting in the formation of chanoclavine-I. GO:1900561 dehydroaustinol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900561 dehydroaustinol metabolism The chemical reactions and pathways involving dehydroaustinol. GO:1900560 austinol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900560 austinol biosynthesis|austinol anabolism|austinol synthesis|austinol formation The chemical reactions and pathways resulting in the formation of austinol. GO:1900563 dehydroaustinol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900563 dehydroaustinol anabolism|dehydroaustinol synthesis|dehydroaustinol formation|dehydroaustinol biosynthesis The chemical reactions and pathways resulting in the formation of dehydroaustinol. GO:1900562 dehydroaustinol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900562 dehydroaustinol degradation|dehydroaustinol catabolism|dehydroaustinol breakdown The chemical reactions and pathways resulting in the breakdown of dehydroaustinol. CHEBI:35740 liposaccharide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35740 CHEBI:11750 3-sn-phosphatidyl-L-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_11750 CHEBI:35742 tetracarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35742 GO:1900570 diorcinol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900570 diorcinol metabolism The chemical reactions and pathways involving diorcinol. UBERON:0002394 bile duct biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002394 gall duct|bile tube|hepatic duct|biliary duct Any of the ducts that form the biliary tree, carrying bile from the liver to the small intestine. CHEBI:35741 glycerolipid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35741 CHEBI:35744 carbocyclic fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35744 CHEBI:35743 pentacarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35743 UBERON:0002391 lymph biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002391 lympha Lymph is the fluid that is formed when interstitial fluid enters the conduits of the lymphatic system through lymph capillaries[WP]. CHEBI:35746 fatty aldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35746 UBERON:0002390 hematopoietic system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002390 haematological system|Blutbildungssystem|hemopoietic system|haematopoietic system|hematological system|organa haemopoietica|hematolymphoid system|haemopoietic system Anatomical system that is involved in the production of hematopoietic cells. GO:0071679 commissural neuron axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071679 commissural neuron axon pathfinding The process in which the migration of an axon growth cone of a commissural neuron is directed to its target in the brain in response to a combination of attractive and repulsive cues. GO:0071678 olfactory bulb axon guidance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071678 olfactory bulb axon pathfinding The process in which the migration of an axon growth cone of a neuron in the olfactory bulb is directed to its target in the brain in response to a combination of attractive and repulsive cues. GO:0071677 positive regulation of mononuclear cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071677 stimulation of mononuclear cell migration|up-regulation of mononuclear cell migration|activation of mononuclear cell migration|up regulation of mononuclear cell migration|upregulation of mononuclear cell migration Any process that increases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body. GO:0071676 negative regulation of mononuclear cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071676 down-regulation of mononuclear cell migration|downregulation of mononuclear cell migration|down regulation of mononuclear cell migration|inhibition of mononuclear cell migration Any process that decreases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body. UBERON:0002397 maxilla biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002397 maxillae|maxillary bone|upper jaw bone The bone which normally forms the lateral upper jaw in osteichthyans, including tetrapods. GO:0071675 regulation of mononuclear cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071675 Any process that modulates the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body. UBERON:0002396 vomer biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002396 vomer bone|prevomer the triangular flat bone of the nasal septum GO:0071674 mononuclear cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071674 The movement of a mononuclear cell within or between different tissues and organs of the body. GO:0071673 positive regulation of smooth muscle cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071673 stimulation of smooth muscle cell chemotaxis|up-regulation of smooth muscle cell chemotaxis|upregulation of smooth muscle cell chemotaxis|up regulation of smooth muscle cell chemotaxis|activation of smooth muscle cell chemotaxis Any process that activates or increases the frequency, rate, or extent of smooth muscle cell chemotaxis. GO:0071672 negative regulation of smooth muscle cell chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071672 down-regulation of smooth muscle cell chemotaxis|inhibition of smooth muscle cell chemotaxis|down regulation of smooth muscle cell chemotaxis|downregulation of smooth muscle cell chemotaxis Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell chemotaxis. UBERON:0002398 manus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002398 fore paw|hand region|forelimb autopod|forelimb autopodium|fore-paw|forefoot of quadruped|fore foot|forefeet|forefoot|forepaw|hand|terminal segment of free upper limb distal segment of the fore limb, including carpal region, metacarpal region and digits. GO:1900579 (17Z)-protosta-17(20),24-dien-3beta-ol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900579 (17Z)-protosta-17(20),24-dien-3beta-ol metabolism The chemical reactions and pathways involving (17Z)-protosta-17(20),24-dien-3beta-ol. GO:1900576 gerfelin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900576 gerfelin metabolism The chemical reactions and pathways involving gerfelin. CHEBI:35715 nitro compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35715 GO:1900575 emodin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900575 emodin formation|emodin biosynthesis|emodin anabolism|emodin synthesis The chemical reactions and pathways resulting in the formation of emodin. CHEBI:35714 polycyclic olefin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35714 GO:1900578 gerfelin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900578 gerfelin synthesis|gerfelin formation|gerfelin biosynthesis|gerfelin anabolism The chemical reactions and pathways resulting in the formation of gerfelin. CHEBI:35717 sedative biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35717 CHEBI:35716 C-nitro compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35716 GO:1900577 gerfelin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900577 gerfelin catabolism|gerfelin degradation|gerfelin breakdown The chemical reactions and pathways resulting in the breakdown of gerfelin. GO:1900572 diorcinol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900572 diorcinol synthesis|diorcinol biosynthesis|diorcinol formation|diorcinol anabolism The chemical reactions and pathways resulting in the formation of diorcinol. CHEBI:35719 sulfamic acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35719 GO:1900571 diorcinol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900571 diorcinol catabolism|diorcinol degradation|diorcinol breakdown The chemical reactions and pathways resulting in the breakdown of diorcinol. CHEBI:35718 antifungal agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35718 GO:1900574 emodin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900574 emodin catabolism|emodin degradation|emodin breakdown The chemical reactions and pathways resulting in the breakdown of emodin. GO:1900573 emodin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900573 emodin metabolism The chemical reactions and pathways involving emodin. CL:2000019 compound eye photoreceptor cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000019 Any photoreceptor cell that is part of a compound eye. GO:1900581 (17Z)-protosta-17(20),24-dien-3beta-ol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900581 (17Z)-protosta-17(20),24-dien-3beta-ol biosynthesis|(17Z)-protosta-17(20),24-dien-3beta-ol anabolism|(17Z)-protosta-17(20),24-dien-3beta-ol synthesis|(17Z)-protosta-17(20),24-dien-3beta-ol formation The chemical reactions and pathways resulting in the formation of (17Z)-protosta-17(20),24-dien-3beta-ol. UBERON:0002384 connective tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002384 Bindegewebe|portion of connective tissue|textus connectivus Tissue with cells that deposit non-polarized extracellular matrix including connective tissue fibers and ground substance. GO:1900580 (17Z)-protosta-17(20),24-dien-3beta-ol catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900580 (17Z)-protosta-17(20),24-dien-3beta-ol degradation|(17Z)-protosta-17(20),24-dien-3beta-ol breakdown|(17Z)-protosta-17(20),24-dien-3beta-ol catabolism The chemical reactions and pathways resulting in the breakdown of (17Z)-protosta-17(20),24-dien-3beta-ol. CHEBI:35711 ursane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35711 CHEBI:35710 pinane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35710 CL:2000018 endothelial cell of coronary artery biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000018 Any endothelial cell of artery that is part of a coronary artery. UBERON:0002380 trapezius muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002380 spinotrapezius|musculus trapezius|trapezius A large superficial muscle that extends longitudinally from the occipital bone to the lower thoracic vertebrae and laterally to the spine of the scapula (shoulder blade). Its functions are to move the scapulae and support the arm. The trapezius has three functional regions: the superior region (descending part), which supports the weight of the arm; the intermediate region (transverse part), which retracts the scapulae; and the inferior region (ascending part), which medially rotates and depresses the scapulae. [WP,unvetted]. CHEBI:35713 polycyclic alkane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35713 UBERON:0002389 manual digit biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002389 hand digit|forelimb digit|fore digit|finger|manual digit (phalangeal portion) plus soft tissue|digit of hand|digitus manus|digit of manus A digit that is part of a manus (hand). UBERON:0002386 forelimb zeugopod biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002386 zeugopod of brachial region|antebrachial region|arm zeugopod|middle limb segment of proximal segment of free upper limb|zeugopod of proximal segment of free upper limb|fore epipodium|intermediate segment of free upper limb|wing zeugopod|antibrachium|regio antebrachialis|arm middle limb segment|forelimb zygopod|zeugopod of forelimb|antebrachium|forelimb epipodium|middle limb segment of forelimb|brachial region middle limb segment|antebrachium|middle limb segment of arm|zeugopod of arm|forearm|lower segment of arm|brachial region zeugopod|lower arm|middle limb segment of brachial region|forelimb zeugopodium The middle limb segment of the pectoral free limb, between the autopod and stylopod segments. Includes as parts the forelimb zeugopodial skeleton, which includes as parts the radius and ulna, or their cartilage precursors, or evolutionary variants. UBERON:0002385 muscle tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002385 muscular tissue|portion of muscle tissue|textus muscularis Muscle tissue is a contractile tissue made up of actin and myosin fibers[GO]. UBERON:0002387 pes biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002387 hind-paw|hindpaw|foot|terminal segment of free lower limb|hind limb autopodium|hindfoot|hindfeet|hind paw|hindlimb autopodium|hindlimb distal free limb segment|hindlimb autopod|pes|hind foot|hindfoot of quadruped distal portion of the hind limb, including tarsal region, metatarsal region and digits. GO:0071693 protein transport within extracellular region biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071693 The directed movement of proteins in the extracellular region, by means of some agent such as a transporter or pore. GO:0071692 protein localization to extracellular region biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071692 protein localisation in extracellular region|protein localization in extracellular region Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location. GO:0071691 cardiac muscle thin filament assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071691 The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in cardiac muscle. GO:0071690 cardiac muscle myosin thick filament assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071690 The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in cardiac muscle. PR:000045358 insulin family protein biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000045358 fam:INS A protein that is a translation product of a gene that encodes a standalone Insulin (Pfam:PF00049) domain preceded by a signal peptide. GO:1900587 arugosin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900587 arugosin biosynthesis|arugosin synthesis|arugosin formation|arugosin anabolism The chemical reactions and pathways resulting in the formation of arugosin. CHEBI:35725 isopropyl ester biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35725 GO:1900586 arugosin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900586 arugosin degradation|arugosin breakdown|arugosin catabolism The chemical reactions and pathways resulting in the breakdown of arugosin. CL:2000000 epidermal melanocyte biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000000 Any melanocyte that is part of a epidermis. GO:1900589 violaceol I catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900589 violaceol I degradation|violaceol I breakdown|violaceol I catabolism The chemical reactions and pathways resulting in the breakdown of violaceol I. UBERON:2000175 posterior lateral line nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_2000175 caudal lateral line nerve Cranial nerve which enters the brain between cranial nerves VIII and IX; contains afferents and sensory efferents to the posterior lateral line ganglion and middle ganglion. Fibers from the posterior lateral line ganglion innervate the occipital dorsal lateral line and trunk lateral lines. GO:1900588 violaceol I metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900588 violaceol I metabolism The chemical reactions and pathways involving violaceol I. CHEBI:35727 triazoles biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35727 GO:1900583 o-orsellinic acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900583 o-orsellinic acid degradation|o-orsellinic acid breakdown|o-orsellinic acid catabolism The chemical reactions and pathways resulting in the breakdown of o-orsellinic acid. GO:1900582 o-orsellinic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900582 o-orsellinic acid metabolism The chemical reactions and pathways involving o-orsellinic acid. GO:1900585 arugosin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900585 arugosin metabolism The chemical reactions and pathways involving arugosin. GO:1900584 o-orsellinic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900584 o-orsellinic acid biosynthesis|o-orsellinic acid synthesis|o-orsellinic acid formation|o-orsellinic acid anabolism The chemical reactions and pathways resulting in the formation of o-orsellinic acid. GO:1900590 violaceol I biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900590 violaceol I synthesis|violaceol I formation|violaceol I biosynthesis|violaceol I anabolism The chemical reactions and pathways resulting in the formation of violaceol I. UBERON:0002371 bone marrow biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002371 medulla ossea|medulla of bone|medullary bone|medulla ossium the soft tissue that fills the cavities of bones UBERON:0002370 thymus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002370 thymus gland|thymus organ Anatomical structure of largely lymphoid tissue that functions in cell-mediated immunity by being the site where T cells develop. GO:1900592 violaceol II catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900592 violaceol II catabolism|violaceol II degradation|violaceol II breakdown The chemical reactions and pathways resulting in the breakdown of violaceol II. GO:1900591 violaceol II metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900591 violaceol II metabolism The chemical reactions and pathways involving violaceol II. CL:2000005 brain macroglial cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000005 Any macroglial cell that is part of a brain. CHEBI:35722 sulfated glycosaminoglycan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35722 CHEBI:35721 heparan sulfates biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35721 CL:2000004 pituitary gland cell biolink:Cell go-plus http://purl.obolibrary.org/obo/CL_2000004 Any cell that is part of a pituitary gland. CHEBI:35724 carbohydrate sulfate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35724 UBERON:0002378 muscle of abdomen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002378 abdomen muscle|abdominal muscle|muscle organ of abdomen|abdominal wall musculature|abdominal wall muscle|abdomen muscle organ Muscle (organ) which is a part of the abdomen. Examples: external oblique, rectus abdominis. GO:0071699 olfactory placode morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071699 The process in which the anatomical structures of the olfactory placode are generated and organized. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity. GO:0071698 olfactory placode development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071698 The progression of the olfactory placode over time from its initial formation until its mature state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity. GO:0071697 ectodermal placode morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071697 The process in which the anatomical structures of an ectodermal placode are generated and organized. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm. UBERON:0002374 metacarpal bone biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002374 metacarpal A bone that is part of the metacarpal skeleton. GO:0071696 ectodermal placode development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071696 The progression of an ectodermal placode over time from its initial formation until its mature state. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm. GO:0071695 anatomical structure maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071695 A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure to attain its fully functional state. UBERON:0002377 muscle of neck biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002377 muscle organ of neck|neck muscle organ|muscle organ of neck (volume)|neck (volume) muscle organ|neck muscle Any muscle that is part of the cervical (neck) region. GO:0071694 maintenance of protein location in extracellular region biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071694 Any process in which a protein is maintained in a specific location within the extracellular region and is prevented from moving elsewhere. UBERON:0002376 cranial muscle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002376 muscle organ of head|cephalic musculature|adult head muscle organ|head muscle organ|musculus caput|head muscles|muscle of head|cranial muscle|cephalic muscle|head muscle|muscle organ of adult head Any skeletal muscle that is part of the head region. CHEBI:21099 D-tagaturonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21099 GO:1900914 regulation of octadecene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900914 regulation of octadecene anabolism|regulation of octadecene synthesis|regulation of 1-octadecene biosynthetic process|regulation of octadecene formation|regulation of octadecene biosynthesis Any process that modulates the frequency, rate or extent of octadecene biosynthetic process. GO:1900913 positive regulation of olefin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900913 up regulation of olefin biosynthetic process|positive regulation of olefin anabolism|activation of olefin biosynthesis|activation of olefin biosynthetic process|up regulation of olefin anabolism|positive regulation of olefin synthesis|up regulation of olefin biosynthesis|up regulation of olefin synthesis|positive regulation of olefin biosynthesis|positive regulation of olefin formation|up regulation of olefin formation|upregulation of olefin anabolism|up-regulation of olefin biosynthetic process|upregulation of olefin synthesis|activation of olefin anabolism|up-regulation of olefin biosynthesis|upregulation of olefin formation|activation of olefin synthesis|up-regulation of olefin anabolism|upregulation of olefin biosynthetic process|activation of olefin formation|up-regulation of olefin synthesis|upregulation of olefin biosynthesis|up-regulation of olefin formation Any process that activates or increases the frequency, rate or extent of olefin biosynthetic process. GO:1900916 positive regulation of octadecene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900916 up-regulation of octadecene anabolism|positive regulation of octadecene biosynthesis|activation of 1-octadecene biosynthetic process|up-regulation of octadecene synthesis|activation of octadecene anabolism|activation of octadecene biosynthesis|up-regulation of octadecene formation|up-regulation of octadecene biosynthetic process|up-regulation of 1-octadecene biosynthetic process|activation of octadecene synthesis|positive regulation of octadecene anabolism|up-regulation of octadecene biosynthesis|activation of octadecene formation|up regulation of octadecene anabolism|positive regulation of octadecene synthesis|upregulation of octadecene biosynthetic process|up regulation of octadecene synthesis|upregulation of 1-octadecene biosynthetic process|positive regulation of octadecene formation|up regulation of octadecene formation|upregulation of octadecene biosynthesis|upregulation of octadecene anabolism|up regulation of octadecene biosynthetic process|upregulation of octadecene synthesis|activation of octadecene biosynthetic process|up regulation of 1-octadecene biosynthetic process|positive regulation of 1-octadecene biosynthetic process|upregulation of octadecene formation|up regulation of octadecene biosynthesis Any process that activates or increases the frequency, rate or extent of octadecene biosynthetic process. GO:0022871 protein-N(PI)-phosphohistidine-sorbose phosphotransferase system transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022871 sorbose PTS transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sorbose(out) = protein histidine + sorbose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. CHEBI:45064 phosphite(3-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_45064 GO:1900915 negative regulation of octadecene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900915 down-regulation of 1-octadecene biosynthetic process|negative regulation of 1-octadecene biosynthetic process|inhibition of 1-octadecene biosynthetic process|negative regulation of octadecene biosynthesis|down-regulation of octadecene biosynthesis|inhibition of octadecene biosynthetic process|down-regulation of octadecene anabolism|negative regulation of octadecene anabolism|inhibition of octadecene biosynthesis|down-regulation of octadecene synthesis|negative regulation of octadecene synthesis|down-regulation of octadecene formation|negative regulation of octadecene formation|downregulation of octadecene anabolism|inhibition of octadecene anabolism|down regulation of octadecene biosynthetic process|downregulation of octadecene synthesis|down regulation of octadecene anabolism|down regulation of 1-octadecene biosynthetic process|inhibition of octadecene synthesis|downregulation of octadecene formation|downregulation of octadecene biosynthetic process|downregulation of 1-octadecene biosynthetic process|down regulation of octadecene synthesis|down regulation of octadecene biosynthesis|inhibition of octadecene formation|down regulation of octadecene formation|downregulation of octadecene biosynthesis|down-regulation of octadecene biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of octadecene biosynthetic process. GO:0022870 protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022870 mannose PTS transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + mannose(out) = protein histidine + mannose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. GO:1900910 positive regulation of olefin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900910 activation of olefin metabolism|up-regulation of olefin metabolic process|activation of olefin metabolic process|up regulation of olefin metabolism|positive regulation of olefin metabolism|up regulation of olefin metabolic process|up-regulation of olefin metabolism|upregulation of olefin metabolic process|upregulation of olefin metabolism Any process that activates or increases the frequency, rate or extent of olefin metabolic process. GO:0022873 protein-N(PI)-phosphohistidine-maltose phosphotransferase system transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022873 maltose PTS transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + maltose(out) = protein histidine + maltose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. GO:0022872 protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022872 mannitol PTS transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + mannitol(out) = protein histidine + mannitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. GO:0007239 obsolete activation of Hog1 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007239 activation of Hog1 OBSOLETE. (Was not defined before being made obsolete). GO:1900912 negative regulation of olefin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900912 down-regulation of olefin synthesis|negative regulation of olefin synthesis|downregulation of olefin biosynthesis|down-regulation of olefin formation|negative regulation of olefin formation|down-regulation of olefin biosynthetic process|inhibition of olefin anabolism|downregulation of olefin anabolism|inhibition of olefin synthesis|downregulation of olefin synthesis|down regulation of olefin anabolism|down-regulation of olefin biosynthesis|negative regulation of olefin biosynthesis|inhibition of olefin biosynthesis|inhibition of olefin biosynthetic process|downregulation of olefin formation|inhibition of olefin formation|down regulation of olefin synthesis|down regulation of olefin formation|down regulation of olefin biosynthetic process|down-regulation of olefin anabolism|downregulation of olefin biosynthetic process|negative regulation of olefin anabolism|down regulation of olefin biosynthesis Any process that stops, prevents or reduces the frequency, rate or extent of olefin biosynthetic process. GO:0022875 protein-N(PI)-phosphohistidine-galactitol phosphotransferase system transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022875 galactitol PTS transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + galactitol(out) = protein histidine + galactitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. GO:0007238 obsolete activation of Pbs2 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007238 activation of Pbs2 OBSOLETE. (Was not defined before being made obsolete). GO:1900911 regulation of olefin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900911 regulation of olefin anabolism|regulation of olefin synthesis|regulation of olefin formation|regulation of olefin biosynthesis Any process that modulates the frequency, rate or extent of olefin biosynthetic process. GO:0022874 protein-N(PI)-phosphohistidine-cellobiose phosphotransferase system transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022874 cellobiose PTS transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + cellobiose(out) = protein histidine + cellobiose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. GO:0007237 obsolete activation of Ssk2/Ssk22 proteins biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007237 activation of Ssk2/Ssk22 proteins OBSOLETE. (Was not defined before being made obsolete). GO:0007236 obsolete activation of Ssk1 protein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007236 activation of Ssk1 protein OBSOLETE. (Was not defined before being made obsolete). GO:0046844 chorion micropyle formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046844 Establishment of the micropyle, a single cone-shaped specialization of the chorion that allows sperm entry into the egg prior to fertilization. GO:0046843 dorsal appendage formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046843 Establishment of the dorsal filaments, elaborate specializations of the chorion that protrude from the anterior end of the egg and facilitate embryonic respiration. GO:0007235 obsolete activation of Ypd1 protein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007235 activation of Ypd1 protein OBSOLETE. (Was not defined before being made obsolete). GO:0046842 trisporic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046842 trisporic acid anabolism|trisporic acid synthesis|trisporic acid formation|trisporic acid biosynthesis The chemical reactions and pathways resulting in the formation of trisporic acid. GO:0007234 osmosensory signaling via phosphorelay pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007234 signal transduction during osmotic stress via two-component system|osmolarity sensing via two-component system|osmosensory signalling pathway via two-component system|osmolarity signalling pathway via two-component system|osmosensory signaling pathway via two-component system|osmolarity signaling pathway via two-component system A series of molecular signals generated in response to osmotic change, as mediated through a phosphorelay system. GO:0046841 trisporic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046841 trisporic acid metabolism The chemical reactions and pathways involving trisporic acid, a carotenoic acid derivative used as a pheromone in some species of Zygomycota. GO:0007233 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007233 GO:0007232 osmosensory signaling pathway via Sho1 osmosensor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007232 osmosensory signalling pathway via Sho1 osmosensor|signal transduction during osmotic stress via Sho1 osmosensor A series of molecular signals generated in response to osmotic change, as mediated through a Sho1 osmosensor system. GO:0046840 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046840 GO:0007231 osmosensory signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007231 osmolarity sensing signalling pathway|osmolarity sensing signaling pathway|osmosensory signal transduction|osmolarity sensing|signal transduction during osmotic stress|osmosensory signalling pathway The series of molecular signals initiated in response to osmotic change. CHEBI:84666 (25S)-3-oxocholest-4-en-26-oyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84666 GO:0007230 obsolete calcium-o-sensing receptor pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007230 calcium-o-sensing receptor pathway OBSOLETE. (Was not defined before being made obsolete). CHEBI:84665 triacylglycerol 50:1 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84665 GO:0071808 satellite fibril biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071808 An axoneme part that is found in the flagella of mammalian sperm and is located in the middle piece between the outer dense fibers (on the concave side of outer dense fibers as seen in cross-section). GO:0071807 replication fork arrest involved in DNA replication termination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071807 A replication fork arrest process that contributes to the termination of DNA replication. GO:0071806 protein transmembrane transport biolink:BiologicalProcess go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0071806 protein membrane transport The process in which a protein is transported across a membrane. GO:0046849 bone remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046849 Wikipedia:Bone_remodeling bone remodelling The continuous turnover of bone matrix and mineral that involves first, an increase in resorption (osteoclastic activity) and later, reactive bone formation (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium homeostasis. An imbalance in the regulation of bone resorption and bone formation results in many of the metabolic bone diseases, such as osteoporosis. GO:0071805 potassium ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071805 high-affinity potassium ion import|high affinity potassium ion uptake|high affinity potassium ion import|high-affinity potassium ion uptake|potassium ion membrane transport A process in which a potassium ion is transported from one side of a membrane to the other. GO:0071804 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0071804 GO:0046848 hydroxyapatite binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046848 hydroxylapatite binding Interacting selectively and non-covalently with hydroxyapatite, the calcium phosphate mineral of formula Ca10(PO4)6(OH)2 found both in rocks of nonorganic origin and as a component of bone and dentin. GO:0071803 positive regulation of podosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071803 upregulation of podosome assembly|up regulation of podosome assembly|activation of podosome assembly|stimulation of podosome assembly|up-regulation of podosome assembly Any process that activates or increases the rate or extent of podosome assembly. GO:0046847 filopodium assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046847 filopodia biosynthesis|filopodia formation|filopodium formation The assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone. GO:0071802 negative regulation of podosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071802 down regulation of podosome assembly|downregulation of podosome assembly|down-regulation of podosome assembly|inhibition of podosome assembly Any process that stops, prevents or reduces the rate or extent of podosome assembly. GO:0046846 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046846 CHEBI:142734 N-acyl hemiaminal biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142734 GO:0046845 branched duct epithelial cell fate determination, open tracheal system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046845 branch cell fate determination Allocation of a set number of cells to each primary branch in an open tracheal system, prior to the onset of cell migration. This establishes different domains of cells within the tracheal placode. GO:0071801 regulation of podosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071801 Any process that modulates the frequency, rate or extent of podosome assembly. GO:0071800 podosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071800 The aggregation, arrangement and bonding together of a set of components to form a podosome, an actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell. GO:0022877 protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022877 fructose PTS transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + fructose(out) = protein histidine + fructose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. GO:0022876 protein-N(PI)-phosphohistidine-galactosamine phosphotransferase system transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022876 galactosamine PTS transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + galactosamine(out) = protein histidine + galactosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. GO:0022879 protein-N(PI)-phosphohistidine-trehalose phosphotransferase system transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022879 trehalose PTS transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + trehalose(out) = protein histidine + trehalose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. GO:0022878 protein-N(PI)-phosphohistidine-sucrose phosphotransferase system transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022878 MetaCyc:SUCROSEPHOSPHO-RXN|RHEA:49236 sucrose PTS transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sucrose(out) = protein histidine + sucrose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. GO:1900918 negative regulation of octadecene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900918 downregulation of octadecene metabolic process|down regulation of octadecene metabolic process|inhibition of octadecene metabolic process|down-regulation of octadecene metabolism|negative regulation of octadecene metabolism|inhibition of octadecene metabolism|down-regulation of octadecene metabolic process|down regulation of octadecene metabolism|downregulation of octadecene metabolism Any process that stops, prevents or reduces the frequency, rate or extent of octadecene metabolic process. GO:1900917 regulation of octadecene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900917 regulation of octadecene metabolism Any process that modulates the frequency, rate or extent of octadecene metabolic process. GO:1900919 positive regulation of octadecene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900919 activation of octadecene metabolism|up regulation of octadecene metabolism|positive regulation of octadecene metabolism|upregulation of octadecene metabolic process|up-regulation of octadecene metabolism|up-regulation of octadecene metabolic process|activation of octadecene metabolic process|upregulation of octadecene metabolism|up regulation of octadecene metabolic process Any process that activates or increases the frequency, rate or extent of octadecene metabolic process. GO:1900925 positive regulation of glycine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900925 up-regulation of glycine import|activation of glycine import|positive regulation of glycine import|up regulation of glycine import|upregulation of glycine import Any process that activates or increases the frequency, rate or extent of glycine import. GO:1900924 negative regulation of glycine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900924 negative regulation of glycine import|down-regulation of glycine import|downregulation of glycine import|down regulation of glycine import|inhibition of glycine import Any process that stops, prevents or reduces the frequency, rate or extent of glycine import into a cell. GO:1900927 negative regulation of L-threonine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900927 downregulation of L-threonine import|down regulation of L-threonine import|inhibition of L-threonine import|downregulation of L-threonine uptake|inhibition of L-threonine uptake|down regulation of L-threonine uptake|down-regulation of L-threonine import|negative regulation of L-threonine uptake|down-regulation of L-threonine uptake Any process that stops, prevents or reduces the frequency, rate or extent of L-threonine import into cell. CHEBI:70031 2'-hydroxygenistein biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_70031 GO:1900926 regulation of L-threonine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900926 regulation of L-threonine uptake|regulation of L-threonine import Any process that modulates the frequency, rate or extent of L-threonine import into cell. GO:1900921 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1900921 GO:1900920 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1900920 GO:1900923 regulation of glycine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900923 regulation of glycine import Any process that modulates the frequency, rate or extent of glycine import into a cell. GO:0007249 I-kappaB kinase/NF-kappaB signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007249 NF-kappaB cascade|I-kappaB kinase/NF-kappaB signal transduction|I-kappaB kinase/NF-kappaB cascade|p50-dependent NF-kappaB signaling|canonical NF-kappaB signaling cascade|activation of the inhibitor of kappa kinase The process in which a signal is passed on to downstream components within the cell through the I-kappaB-kinase (IKK)-dependent activation of NF-kappaB. The cascade begins with activation of a trimeric IKK complex (consisting of catalytic kinase subunits IKKalpha and/or IKKbeta, and the regulatory scaffold protein NEMO) and ends with the regulation of transcription of target genes by NF-kappaB. In a resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription. CHEBI:69042 7-demethylsuberosin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_69042 GO:0007248 obsolete nuclear translocation of MAPK (mating sensu Saccharomyces) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007248 nuclear translocation of MAPK (mating sensu Saccharomyces) OBSOLETE. Movement of a MAP kinase to the nucleus in the context of transduction of mating pheromone signal, as described for Saccharomyces. SO:0001240 TSS_region biolink:SequenceFeature go-plus http://purl.obolibrary.org/obo/SO_0001240 TSS region The region of a gene from the 5' most TSS to the 3' TSS. GO:1900922 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1900922 GO:0007247 obsolete activation of MAPK (mating sensu Saccharomyces) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007247 activation of MAPK (mating sensu Saccharomyces) OBSOLETE. Upregulation of MAP kinase activity in the context of transduction of mating pheromone signal, as described for Saccharomyces. GO:0046855 inositol phosphate dephosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046855 myo-inositol phosphate dephosphorylation The process of removing a phosphate group from any mono- or polyphosphorylated inositol. GO:0007246 obsolete activation of MAPKK (mating sensu Saccharomyces) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007246 activation of MAPKK (mating sensu Saccharomyces) OBSOLETE. Upregulation of a MAP kinase kinase in the context of transduction of mating pheromone signal, as described for Saccharomyces. GO:0046854 phosphatidylinositol phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046854 PIP biosynthesis|phosphatidylinositol phosphate phosphorylation|PtdInsP biosynthesis|phosphatidylinositol phosphate biosynthetic process|phosphoinositide phosphorylation The process of introducing one or more phosphate groups into a phosphatidylinositol, any glycerophosphoinositol having one phosphatidyl group esterified to one of the hydroxy groups of inositol. GO:0007245 obsolete activation of MAPKKK (mating sensu Saccharomyces) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007245 activation of MAPKKK (mating sensu Saccharomyces) OBSOLETE. Upregulation of MAPKKK activity in the context of transduction of mating pheromone signal, as described for Saccharomyces. GO:0046853 obsolete inositol or phosphatidylinositol phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046853 myo-inositol and derivative phosphorylation|myo-inositol or phosphatidyl-myo-inositol phosphorylation|inositol and derivative phosphorylation|inositol or phosphatidylinositol phosphorylation OBSOLETE. The process of introducing a phosphate group into inositol or a phosphatidylinositol. Inositol is the cyclic alcohol 1,2,3,4,5,6-cyclohexanehexol, which is widely distributed in nature and acts as a growth factor in animals and microorganisms. GO:0007244 obsolete MAPKKK cascade (mating sensu Saccharomyces) biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007244 MAPKKK cascade (mating sensu Saccharomyces) OBSOLETE. MAPKKK cascade involved in transduction of mating pheromone signal, as described in Saccharomyces. GO:0046852 positive regulation of bone remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046852 upregulation of bone remodeling|up regulation of bone remodeling|activation of bone remodeling|stimulation of bone remodeling|up-regulation of bone remodeling Any process that activates or increases the frequency, rate or extent of bone remodeling. GO:0046851 negative regulation of bone remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046851 down regulation of bone remodeling|downregulation of bone remodeling|down-regulation of bone remodeling|inhibition of bone remodeling Any process that stops, prevents, or reduces the frequency, rate or extent of bone remodeling. GO:0007243 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007243 GO:0046850 regulation of bone remodeling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046850 Any process that modulates the frequency, rate or extent of bone remodeling, the processes of bone formation and resorption that combine to maintain skeletal integrity. GO:0007242 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007242 GO:0007241 obsolete inactivation of Hog1 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007241 inactivation of Hog1 OBSOLETE. (Was not defined before being made obsolete). GO:0007240 obsolete nuclear translocation of Hog1 biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007240 nuclear translocation of Hog1 OBSOLETE. (Was not defined before being made obsolete). CHEBI:84675 alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(d18:1/18:0) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84675 GO:0007250 activation of NF-kappaB-inducing kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007250 positive regulation of NF-kappaB-inducing kinase activity|activation of NIK activity The stimulation of the activity of NF-kappaB-inducing kinase through phosphorylation at specific residues. CHEBI:59696 steroid sulfate oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59696 CHEBI:84672 phosphatidylethanol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84672 GO:0046859 hydrogenosomal membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0046859 hydrogenosome membrane The lipid bilayer surrounding a hydrogenosome. GO:0046858 chlorosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0046858 Wikipedia:Chlorosome A large enclosure of aggregated pigment, typically bacteriochlorophyll c (BChl c), that acts as a light-harvesting antenna structure and is characteristic of green photosynthetic bacteria (e.g. Chlorobiaceae). The BChl aggregates are organized into lamellar elements by pigment-pigment rather than pigment-protein interactions. Chlorosomes also contain BChl a, carotenoids, quinones, lipids, and proteins, and are attached to the cytoplasmic membrane via a BChl a-containing protein baseplate. GO:0046857 oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046857 EC:1.7.1.- Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces NAD or NADP. GO:0046856 phosphatidylinositol dephosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046856 PIP catabolism|phosphatidylinositol phosphate dephosphorylation|PtdInsP catabolism|PtdInsP dephosphorylation|phosphatidylinositol phosphate catabolic process|phosphoinositide dephosphorylation The process of removing one or more phosphate groups from a phosphatidylinositol. GO:0022866 obsolete transmembrane 1-electron transfer carrier biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022866 transmembrane one-electron transfer carrier OBSOLETE. Enables transfer of one electron across a membrane. GO:0022865 obsolete transmembrane electron transfer carrier biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022865 TC:5 OBSOLETE. Enables electron flow across a biological membrane, from donors localized on one side of the membrane to acceptors localized on the other side. These systems contribute to or subtract from the membrane potential, depending on the direction of electron flow. They are therefore important to cellular energetics. GO:0022867 obsolete transmembrane 2-electron transfer carrier biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022867 transmembrane two-electron transfer carrier OBSOLETE. Enables transfer of two electrons across a membrane. GO:1900929 regulation of L-tyrosine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900929 regulation of L-tyrosine uptake|regulation of L-tyrosine import Any process that modulates the frequency, rate or extent of L-tyrosine import into the cell. SO:0001236 base biolink:SequenceFeature go-plus SOFA http://purl.obolibrary.org/obo/SO_0001236 http://en.wikipedia.org/wiki/Nucleobase A base is a sequence feature that corresponds to a single unit of a nucleotide polymer. GO:1900928 positive regulation of L-threonine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900928 positive regulation of L-threonine uptake|up regulation of L-threonine uptake|upregulation of L-threonine import|upregulation of L-threonine uptake|up-regulation of L-threonine import|activation of L-threonine import|activation of L-threonine uptake|positive regulation of L-threonine import|up-regulation of L-threonine uptake|up regulation of L-threonine import Any process that activates or increases the frequency, rate or extent of L-threonine import into cell. GO:0022869 protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022869 lactose PTS transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + lactose(out) = protein histidine + lactose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. CHEBI:59699 N,N-dihydroxy-alpha-amino-acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59699 CHEBI:59698 phosphoric acids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59698 GO:1900936 negative regulation of nonadec-1-ene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900936 inhibition of nonadec-1-ene anabolism|inhibition of nonadec-1-ene synthesis|down-regulation of nonadec-1-ene biosynthetic process|negative regulation of nonadec-1-ene biosynthesis|down-regulation of nonadec-1-ene biosynthesis|inhibition of nonadec-1-ene formation|down regulation of nonadec-1-ene anabolism|downregulation of nonadec-1-ene anabolism|down regulation of nonadec-1-ene synthesis|down regulation of nonadec-1-ene formation|downregulation of nonadec-1-ene biosynthesis|downregulation of nonadec-1-ene biosynthetic process|downregulation of nonadec-1-ene synthesis|downregulation of nonadec-1-ene formation|down regulation of nonadec-1-ene biosynthesis|down regulation of nonadec-1-ene biosynthetic process|negative regulation of nonadec-1-ene anabolism|down-regulation of nonadec-1-ene anabolism|inhibition of nonadec-1-ene biosynthetic process|negative regulation of nonadec-1-ene synthesis|down-regulation of nonadec-1-ene synthesis|inhibition of nonadec-1-ene biosynthesis|negative regulation of nonadec-1-ene formation|down-regulation of nonadec-1-ene formation Any process that stops, prevents or reduces the frequency, rate or extent of nonadec-1-ene biosynthetic process. CHEBI:21077 D-ribonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21077 GO:1900935 regulation of nonadec-1-ene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900935 regulation of nonadec-1-ene anabolism|regulation of nonadec-1-ene synthesis|regulation of nonadec-1-ene formation|regulation of nonadec-1-ene biosynthesis Any process that modulates the frequency, rate or extent of nonadec-1-ene biosynthetic process. GO:1900938 regulation of (Z)-nonadeca-1,14-diene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900938 regulation of (Z)-nonadeca-1,14-diene metabolism Any process that modulates the frequency, rate or extent of (Z)-nonadeca-1,14-diene metabolic process. GO:1900937 positive regulation of nonadec-1-ene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900937 activation of nonadec-1-ene biosynthetic process|up-regulation of nonadec-1-ene formation|upregulation of nonadec-1-ene anabolism|activation of nonadec-1-ene biosynthesis|upregulation of nonadec-1-ene synthesis|positive regulation of nonadec-1-ene biosynthesis|upregulation of nonadec-1-ene formation|up regulation of nonadec-1-ene biosynthesis|up regulation of nonadec-1-ene biosynthetic process|up regulation of nonadec-1-ene anabolism|positive regulation of nonadec-1-ene anabolism|up regulation of nonadec-1-ene synthesis|positive regulation of nonadec-1-ene synthesis|up regulation of nonadec-1-ene formation|activation of nonadec-1-ene anabolism|upregulation of nonadec-1-ene biosynthesis|upregulation of nonadec-1-ene biosynthetic process|positive regulation of nonadec-1-ene formation|activation of nonadec-1-ene synthesis|up-regulation of nonadec-1-ene anabolism|activation of nonadec-1-ene formation|up-regulation of nonadec-1-ene biosynthetic process|up-regulation of nonadec-1-ene biosynthesis|up-regulation of nonadec-1-ene synthesis Any process that activates or increases the frequency, rate or extent of nonadec-1-ene biosynthetic process. GO:0007219 Notch signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007219 Wikipedia:Notch_signaling_pathway Notch receptor signaling pathway|Notch receptor signalling pathway|N signalling pathway|Notch-receptor signalling pathway|Notch-receptor signaling pathway|N signaling pathway|Notch signalling pathway A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:1900932 regulation of nonadec-1-ene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900932 regulation of nonadec-1-ene metabolism Any process that modulates the frequency, rate or extent of nonadec-1-ene metabolic process. GO:0007218 neuropeptide signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007218 neuropeptide signalling pathway The series of molecular signals generated as a consequence of a peptide neurotransmitter binding to a cell surface receptor. GO:0022851 GABA-gated chloride ion channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022851 Enables the transmembrane transfer of a chloride ion by a channel that opens when GABA has been bound by the channel complex or one of its constituent parts. GO:1900931 positive regulation of L-tyrosine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900931 up-regulation of L-tyrosine uptake|upregulation of L-tyrosine import|positive regulation of L-tyrosine import|upregulation of L-tyrosine uptake|up regulation of L-tyrosine import|activation of L-tyrosine import|activation of L-tyrosine uptake|up regulation of L-tyrosine uptake|positive regulation of L-tyrosine uptake|up-regulation of L-tyrosine import Any process that activates or increases the frequency, rate or extent of L-tyrosine import into the cell. GO:0007217 tachykinin receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007217 tachykinin signalling pathway The series of molecular signals generated as a consequence of a tachykinin, i.e. a short peptide with the terminal sequence (Phe-X-Gly-Leu-Met-NH2), binding to a cell surface receptor. GO:0022850 serotonin-gated cation-selective channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022850 Reactome:R-HSA-9648983|Reactome:R-HSA-975311 5-hydroxytryptamine-gated receptor-channel|serotonin-activated cation-selective channel activity|serotonin-gated cation channel activity Enables the transmembrane transfer of a cation by a channel that opens when serotonin has been bound by the channel complex or one of its constituent parts. GO:1900934 positive regulation of nonadec-1-ene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900934 up-regulation of nonadec-1-ene metabolism|up regulation of nonadec-1-ene metabolic process|activation of nonadec-1-ene metabolic process|activation of nonadec-1-ene metabolism|positive regulation of nonadec-1-ene metabolism|up regulation of nonadec-1-ene metabolism|up-regulation of nonadec-1-ene metabolic process|upregulation of nonadec-1-ene metabolism|upregulation of nonadec-1-ene metabolic process Any process that activates or increases the frequency, rate or extent of nonadec-1-ene metabolic process. GO:0007216 G protein-coupled glutamate receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007216 metabotropic glutamate receptor signaling pathway|G-protein coupled glutamate receptor signaling pathway|metabotropic glutamate receptor signalling pathway A series of molecular signals initiated by glutamate binding to a glutamate receptor on the surface of the target cell, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. Ends with regulation of a downstream cellular process, e.g. transcription. GO:0022853 active ion transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022853 Enables the transfer of an ion from one side of a membrane to the other up the solute's concentration gradient. This is carried out by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction. GO:0022852 glycine-gated chloride ion channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022852 Enables the transmembrane transfer of a chloride ion by a channel that opens when glycine has been bound by the channel complex or one of its constituent parts. GO:0007215 glutamate receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007215 glutamate signalling pathway|glutamate signaling pathway A series of molecular signals initiated by the binding of glutamate to a glutamate receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:1900933 negative regulation of nonadec-1-ene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900933 down-regulation of nonadec-1-ene metabolism|down-regulation of nonadec-1-ene metabolic process|negative regulation of nonadec-1-ene metabolism|inhibition of nonadec-1-ene metabolic process|downregulation of nonadec-1-ene metabolism|down regulation of nonadec-1-ene metabolism|down regulation of nonadec-1-ene metabolic process|inhibition of nonadec-1-ene metabolism|downregulation of nonadec-1-ene metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of nonadec-1-ene metabolic process. GO:0007214 gamma-aminobutyric acid signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007214 4-aminobutyrate signalling pathway|gamma-aminobutyric acid signalling pathway|4-aminobutyrate signaling pathway|GABA signaling pathway|4-aminobutanoate signalling pathway|4-aminobutanoate signaling pathway|GABA signalling pathway The series of molecular signals generated by the binding of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, to a cell surface receptor. GO:0046866 tetraterpenoid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046866 The directed movement of tetraterpenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Tetraterpenoids are terpenoids with eight isoprene units. GO:0007213 G protein-coupled acetylcholine receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007213 G-protein coupled acetylcholine receptor signaling pathway|acetylcholine receptor signalling, muscarinic pathway|muscarinic acetylcholine receptor signaling pathway Any series of molecular signals initiated by an acetylcholine receptor on the surface of the target cell binding to one of its physiological ligands, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction and ends with regulation of a downstream cellular process, e.g. transcription. GO:0046865 terpenoid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046865 The directed movement of terpenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Terpenoids are a class of compounds characterized by an isoprenoid chemical structure and include derivatives with various functional groups. GO:1900930 negative regulation of L-tyrosine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900930 down regulation of L-tyrosine import|inhibition of L-tyrosine uptake|downregulation of L-tyrosine import|down regulation of L-tyrosine uptake|negative regulation of L-tyrosine import|downregulation of L-tyrosine uptake|down-regulation of L-tyrosine import|inhibition of L-tyrosine import|down-regulation of L-tyrosine uptake|negative regulation of L-tyrosine uptake Any process that stops, prevents or reduces the frequency, rate or extent of L-tyrosine import into the cell. GO:0046864 isoprenoid transport biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0046864 The directed movement of isoprenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Isoprenoids comprise a group of compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues. GO:0007212 dopamine receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007212 dopamine receptor signalling pathway The series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands. GO:0046863 ribulose-1,5-bisphosphate carboxylase/oxygenase activator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046863 rubisco activator|ribulose-1,5-bisphosphate carboxylase/oxygenase activase activity|ribulose-bisphosphate carboxylase activase activity|rubisco activase activity Increases the activity of rubisco by the removal of otherwise inhibitory sugar phosphates: RuBP, and in some plants, 2-carboxyarabinitol 1-phosphate. GO:0007211 octopamine or tyramine signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007211 octopamine/tyramine signaling pathway|octopamine or tyramine signalling pathway The series of molecular signals generated as a consequence of octopamine or tyramine binding to a cell surface receptor. Octopamine and tyramine are decarboxylation products of tyrosine, and are the invertebrate counterparts of the vertebrate adrenergic transmitters. CHEBI:45049 2-amino-9-(2-deoxy-5-O-phosphono-beta-D-erythro-pentofuranosyl)-9H-purin-6-ol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_45049 GO:0046862 chromoplast membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0046862 Either of the lipid bilayers that surround a chromoplast and form the chromoplast envelope. GO:0007210 serotonin receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007210 serotonin receptor signalling pathway The series of molecular signals generated as a consequence of a serotonin receptor binding to one of its physiological ligands. GO:0046861 glyoxysomal membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0046861 glyoxysome membrane The lipid bilayer surrounding a glyoxysome. CHEBI:84688 Fe(III)-complexed hydroxamate siderophore biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84688 GO:0046860 glycosome membrane biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0046860 The lipid bilayer surrounding a glycosome. CHEBI:59685 edaxadiene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59685 GO:0071829 plasma lipoprotein particle disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071829 The disaggregation of a plasma lipoprotein particle into its constituent components. GO:0071828 apolipoprotein E recycling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071828 APOE recycling The process in which chylomicron remnant-associated apolipoprotein E is internalized by endocytosis, localized to recycling endosomes and then secreted in association with a high-density lipoprotein particle. CHEBI:59683 antipruritic drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59683 GO:0071827 plasma lipoprotein particle organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071827 plasma lipoprotein particle organisation A protein-lipid complex subunit organization process that results in the formation, disassembly, or alteration of a plasma lipoprotein particle. A plasma lipoprotein particle is a spherical particle with a hydrophobic core of triglycerides and/or cholesterol esters, surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins. GO:0071826 ribonucleoprotein complex subunit organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071826 protein-RNA complex subunit organization|RNA-protein complex subunit organization|ribonucleoprotein complex subunit organisation Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a ribonucleoprotein complex. GO:0046869 iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-aspartato diiron disulfide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046869 RESID:AA0331 iron incorporation into iron-sulphur cluster via tris-L-cysteinyl-L-aspartato diiron disulphide The incorporation of iron into a 2Fe-2S iron-sulfur cluster via tris-L-cysteinyl-L-aspartato diiron disulfide. GO:0071825 protein-lipid complex subunit organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071825 protein-lipid complex subunit organisation Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-lipid complex. GO:0046868 mesosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0046868 Wikipedia:Mesosome An intracellular, often complex, membranous structure, sometimes with additional membranous lamellae inside, found in bacteria. They are associated with synthesis of DNA and secretion of proteins. GO:0071824 protein-DNA complex subunit organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071824 protein-DNA complex subunit organisation|DNA-protein complex subunit organization Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-DNA complex. GO:0046867 carotenoid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046867 The directed movement of carotenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carotenoids are tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail. GO:0071823 protein-carbohydrate complex subunit organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071823 protein-carbohydrate complex subunit organisation Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-carbohydrate complex. OBO:GOCHE_24127 substance with fungicide role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_24127 GO:0022855 protein-N(PI)-phosphohistidine-glucose phosphotransferase system transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022855 glucose PTS transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + glucose(out) = protein histidine + glucose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. GO:0071822 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0071822 GO:0022854 obsolete active large uncharged polar molecule transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022854 active large uncharged polar molecule transmembrane transporter activity OBSOLETE. Catalysis of the transfer of a large uncharged polar molecule from one side of the membrane to the other, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction. GO:0071821 FANCM-MHF complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071821 A protein complex contains the proteins FANCM and MHF, or their orthologs, plays an essential role in DNA remodeling, protects replication forks, and is conserved in eukaryotes. GO:0071820 N-box binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071820 N-box promoter binding|N box binding Interacting selectively and non-covalently with an N-box, a DNA motif with the consensus sequence CACNAG that is found in the promoters of genes expressed preferentially at synapses. GO:0022857 transmembrane transporter activity biolink:MolecularActivity go-plus goslim_drosophila|goslim_generic|goslim_chembl|goslim_yeast http://purl.obolibrary.org/obo/GO_0022857 Reactome:R-HSA-5638209|Reactome:R-HSA-429036|Reactome:R-HSA-1236947|Reactome:R-HSA-6784436|Reactome:R-HSA-5671707|Reactome:R-HSA-6784434 substrate-specific transmembrane transporter activity|uptake transmembrane transporter activity|substrate-specific transporter activity|uptake permease activity Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. GO:0022856 protein-N(PI)-phosphohistidine-sorbitol phosphotransferase system transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022856 sorbitol PTS transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sorbitol(out) = protein histidine + sorbitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. GO:0022859 dephosphorylation-gated channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022859 Enables the transmembrane transfer of a solute by a channel that opens in response to dephosphorylation of one of its constituent parts. GO:0022858 alanine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022858 Enables the transfer of alanine from one side of a membrane to the other. Alanine is 2-aminopropanoic acid. GO:1900939 negative regulation of (Z)-nonadeca-1,14-diene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900939 down regulation of (Z)-nonadeca-1,14-diene metabolism|inhibition of (Z)-nonadeca-1,14-diene metabolic process|inhibition of (Z)-nonadeca-1,14-diene metabolism|down regulation of (Z)-nonadeca-1,14-diene metabolic process|negative regulation of (Z)-nonadeca-1,14-diene metabolism|down-regulation of (Z)-nonadeca-1,14-diene metabolism|downregulation of (Z)-nonadeca-1,14-diene metabolic process|downregulation of (Z)-nonadeca-1,14-diene metabolism|down-regulation of (Z)-nonadeca-1,14-diene metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of (Z)-nonadeca-1,14-diene metabolic process. CHEBI:59687 halimane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59687 CHEBI:59686 halimane diterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59686 GO:1900947 regulation of isoprene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900947 regulation of hemiterpene biosynthetic process|regulation of hemiterpene biosynthesis|regulation of 2-methyl-1,3-butadiene biosynthetic process|regulation of 2-methyl-1,3-butadiene biosynthesis Any process that modulates the frequency, rate or extent of isoprene biosynthetic process. GO:1900946 positive regulation of isoprene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900946 activation of hemiterpene metabolic process|up-regulation of isoprene metabolic process|positive regulation of hemiterpene metabolic process|activation of isoprene metabolic process|up regulation of isoprene metabolism|positive regulation of isoprene metabolism|activation of isoprene metabolism|up-regulation of hemiterpene metabolism|activation of hemiterpene metabolism|up-regulation of 2-methyl-1,3-butadiene metabolic process|activation of 2-methyl-1,3-butadiene metabolic process|up-regulation of 2-methyl-1,3-butadiene metabolism|up-regulation of hemiterpene metabolic process|up regulation of isoprene metabolic process|positive regulation of hemiterpene metabolism|up-regulation of isoprene metabolism|up regulation of hemiterpene metabolism|positive regulation of 2-methyl-1,3-butadiene metabolic process|upregulation of 2-methyl-1,3-butadiene metabolism|up regulation of 2-methyl-1,3-butadiene metabolic process|upregulation of hemiterpene metabolic process|upregulation of isoprene metabolic process|upregulation of isoprene metabolism|upregulation of hemiterpene metabolism|up regulation of 2-methyl-1,3-butadiene metabolism|upregulation of 2-methyl-1,3-butadiene metabolic process|activation of 2-methyl-1,3-butadiene metabolism|positive regulation of 2-methyl-1,3-butadiene metabolism|up regulation of hemiterpene metabolic process Any process that activates or increases the frequency, rate or extent of isoprene metabolic process. GO:1900949 positive regulation of isoprene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900949 up-regulation of hemiterpene biosynthesis|activation of isoprene biosynthetic process|up-regulation of hemiterpene biosynthetic process|activation of hemiterpene biosynthesis|activation of hemiterpene biosynthetic process|up-regulation of 2-methyl-1,3-butadiene biosynthetic process|up-regulation of 2-methyl-1,3-butadiene biosynthesis|positive regulation of hemiterpene biosynthesis|up-regulation of isoprene biosynthetic process|positive regulation of hemiterpene biosynthetic process|up regulation of hemiterpene biosynthesis|up regulation of hemiterpene biosynthetic process|upregulation of 2-methyl-1,3-butadiene biosynthesis|upregulation of 2-methyl-1,3-butadiene biosynthetic process|upregulation of isoprene biosynthetic process|upregulation of hemiterpene biosynthetic process|upregulation of hemiterpene biosynthesis|up regulation of 2-methyl-1,3-butadiene biosynthetic process|up regulation of 2-methyl-1,3-butadiene biosynthesis|positive regulation of 2-methyl-1,3-butadiene biosynthetic process|positive regulation of 2-methyl-1,3-butadiene biosynthesis|activation of 2-methyl-1,3-butadiene biosynthetic process|activation of 2-methyl-1,3-butadiene biosynthesis|up regulation of isoprene biosynthetic process Any process that activates or increases the frequency, rate or extent of isoprene biosynthetic process. GO:1900948 negative regulation of isoprene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900948 down-regulation of isoprene biosynthetic process|inhibition of 2-methyl-1,3-butadiene biosynthesis|inhibition of 2-methyl-1,3-butadiene biosynthetic process|negative regulation of hemiterpene biosynthesis|down-regulation of hemiterpene biosynthesis|negative regulation of hemiterpene biosynthetic process|down-regulation of hemiterpene biosynthetic process|inhibition of isoprene biosynthetic process|downregulation of hemiterpene biosynthetic process|downregulation of hemiterpene biosynthesis|down regulation of 2-methyl-1,3-butadiene biosynthetic process|down regulation of 2-methyl-1,3-butadiene biosynthesis|down regulation of hemiterpene biosynthetic process|down regulation of hemiterpene biosynthesis|inhibition of hemiterpene biosynthesis|downregulation of 2-methyl-1,3-butadiene biosynthetic process|downregulation of 2-methyl-1,3-butadiene biosynthesis|inhibition of hemiterpene biosynthetic process|down regulation of isoprene biosynthetic process|downregulation of isoprene biosynthetic process|negative regulation of 2-methyl-1,3-butadiene biosynthesis|negative regulation of 2-methyl-1,3-butadiene biosynthetic process|down-regulation of 2-methyl-1,3-butadiene biosynthesis|down-regulation of 2-methyl-1,3-butadiene biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of isoprene biosynthetic process. GO:1900943 positive regulation of (Z)-nonadeca-1,14-diene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900943 up-regulation of (Z)-nonadeca-1,14-diene synthesis|positive regulation of (Z)-nonadeca-1,14-diene biosynthesis|up-regulation of (Z)-nonadeca-1,14-diene formation|up regulation of (Z)-nonadeca-1,14-diene biosynthetic process|up regulation of (Z)-nonadeca-1,14-diene biosynthesis|upregulation of (Z)-nonadeca-1,14-diene anabolism|upregulation of (Z)-nonadeca-1,14-diene synthesis|upregulation of (Z)-nonadeca-1,14-diene formation|upregulation of (Z)-nonadeca-1,14-diene biosynthetic process|upregulation of (Z)-nonadeca-1,14-diene biosynthesis|up regulation of (Z)-nonadeca-1,14-diene anabolism|activation of (Z)-nonadeca-1,14-diene anabolism|positive regulation of (Z)-nonadeca-1,14-diene anabolism|up regulation of (Z)-nonadeca-1,14-diene synthesis|activation of (Z)-nonadeca-1,14-diene synthesis|positive regulation of (Z)-nonadeca-1,14-diene synthesis|up regulation of (Z)-nonadeca-1,14-diene formation|up-regulation of (Z)-nonadeca-1,14-diene biosynthesis|activation of (Z)-nonadeca-1,14-diene biosynthetic process|activation of (Z)-nonadeca-1,14-diene biosynthesis|up-regulation of (Z)-nonadeca-1,14-diene biosynthetic process|activation of (Z)-nonadeca-1,14-diene formation|positive regulation of (Z)-nonadeca-1,14-diene formation|up-regulation of (Z)-nonadeca-1,14-diene anabolism Any process that activates or increases the frequency, rate or extent of (Z)-nonadeca-1,14-diene biosynthetic process. GO:0022840 leak channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022840 Enables the transport of a solute across a membrane via a narrow pore channel that is open even in an unstimulated or 'resting' state. GO:0007229 integrin-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007229 integrin-mediated signalling pathway A series of molecular signals initiated by the binding of extracellular ligand to an integrin on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:1900942 negative regulation of (Z)-nonadeca-1,14-diene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900942 inhibition of (Z)-nonadeca-1,14-diene synthesis|inhibition of (Z)-nonadeca-1,14-diene formation|downregulation of (Z)-nonadeca-1,14-diene biosynthetic process|downregulation of (Z)-nonadeca-1,14-diene biosynthesis|down regulation of (Z)-nonadeca-1,14-diene anabolism|down regulation of (Z)-nonadeca-1,14-diene biosynthetic process|down regulation of (Z)-nonadeca-1,14-diene biosynthesis|inhibition of (Z)-nonadeca-1,14-diene biosynthetic process|inhibition of (Z)-nonadeca-1,14-diene biosynthesis|downregulation of (Z)-nonadeca-1,14-diene anabolism|down regulation of (Z)-nonadeca-1,14-diene synthesis|down regulation of (Z)-nonadeca-1,14-diene formation|downregulation of (Z)-nonadeca-1,14-diene synthesis|downregulation of (Z)-nonadeca-1,14-diene formation|negative regulation of (Z)-nonadeca-1,14-diene anabolism|down-regulation of (Z)-nonadeca-1,14-diene anabolism|negative regulation of (Z)-nonadeca-1,14-diene synthesis|down-regulation of (Z)-nonadeca-1,14-diene synthesis|inhibition of (Z)-nonadeca-1,14-diene anabolism|negative regulation of (Z)-nonadeca-1,14-diene formation|down-regulation of (Z)-nonadeca-1,14-diene formation|negative regulation of (Z)-nonadeca-1,14-diene biosynthesis|down-regulation of (Z)-nonadeca-1,14-diene biosynthetic process|down-regulation of (Z)-nonadeca-1,14-diene biosynthesis Any process that stops, prevents or reduces the frequency, rate or extent of (Z)-nonadeca-1,14-diene biosynthetic process. GO:0007228 positive regulation of hh target transcription factor activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007228 positive regulation of hedgehog target transcription factor|activation of hh target transcription factor Any process that increases the activity of a transcription factor that activates transcription of Hedgehog-target genes in response to Smoothened signaling. In Drosophila, Cubitus interruptus (Ci) is the only identified transcription factor so far in the Hedgehog signaling pathway. In vertebrates, members of the Gli protein family are activated in this way. Activation of the Gli/Ci transcription factor is distinct from its stabilization, when proteolytic cleavage is inhibited. GO:1900945 negative regulation of isoprene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900945 down-regulation of 2-methyl-1,3-butadiene metabolism|negative regulation of 2-methyl-1,3-butadiene metabolism|down-regulation of hemiterpene metabolic process|negative regulation of hemiterpene metabolic process|down-regulation of isoprene metabolic process|negative regulation of isoprene metabolism|down-regulation of isoprene metabolism|inhibition of 2-methyl-1,3-butadiene metabolism|down-regulation of hemiterpene metabolism|negative regulation of hemiterpene metabolism|inhibition of hemiterpene metabolic process|down-regulation of 2-methyl-1,3-butadiene metabolic process|negative regulation of 2-methyl-1,3-butadiene metabolic process|inhibition of isoprene metabolism|downregulation of isoprene metabolic process|downregulation of hemiterpene metabolism|down regulation of 2-methyl-1,3-butadiene metabolism|down regulation of isoprene metabolic process|downregulation of 2-methyl-1,3-butadiene metabolic process|inhibition of isoprene metabolic process|down regulation of hemiterpene metabolism|down regulation of hemiterpene metabolic process|downregulation of 2-methyl-1,3-butadiene metabolism|inhibition of hemiterpene metabolism|down regulation of isoprene metabolism|down regulation of 2-methyl-1,3-butadiene metabolic process|downregulation of hemiterpene metabolic process|inhibition of 2-methyl-1,3-butadiene metabolic process|downregulation of isoprene metabolism Any process that stops, prevents or reduces the frequency, rate or extent of isoprene metabolic process. GO:0022842 narrow pore channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022842 Enables the transport of a solute across a membrane via a narrow pore channel that may be gated or ungated. GO:0007227 signal transduction downstream of smoothened biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007227 The series of molecular signals that are initiated by the transmembrane protein Smoothened. In the presence of a Hedgehog signaling molecule, the Patched protein no longer inhibits the activity of Smoothened, and Smoothened signals via the Hedgehog signaling complex to activate downstream components of the Hedgehog signaling pathway. GO:1900944 regulation of isoprene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900944 regulation of hemiterpene metabolism|regulation of 2-methyl-1,3-butadiene metabolism|regulation of 2-methyl-1,3-butadiene metabolic process|regulation of hemiterpene metabolic process|regulation of isoprene metabolism Any process that modulates the frequency, rate or extent of isoprene metabolic process. GO:0022841 potassium ion leak channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022841 Enables the transport of a potassium ion across a membrane via a narrow pore channel that is open even in an unstimulated or 'resting' state. GO:0007226 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007226 GO:0007225 patched ligand maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007225 hh protein processing|patched ligand processing|Hedgehog protein processing The posttranslational modification of members of the Hedgehog family of signaling proteins in order for Hedgehog to exert its biological activity. These modifications include cleavage of its signal sequence, autocatalytic protein cleavage and the attachment of sterol groups. CHEBI:21080 ribose diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21080 GO:0046877 regulation of saliva secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046877 Any process that modulates the frequency, rate or extent of the regulated release of saliva from a cell or a tissue. GO:0046876 3,4-didehydroretinal binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046876 opsin|red-sensitive opsin|long-wave-sensitive opsin|short-wave-sensitive opsin|green-sensitive opsin|UV-sensitive opsin|violet-sensitive opsin|blue-sensitive opsin Interacting selectively and non-covalently with 3,4-didehydroretinal, a form of retinal that plays a role in the visual process in freshwater fish and some amphibians analogous to that of all-trans retinal in other vertebrates. 3,4-didehydro-11-cis-retinal combines with an opsin to form cyanopsin (cone) or porphyropsin (rod). GO:0007224 smoothened signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007224 Wikipedia:Hedgehog_signaling_pathway smoothened signalling pathway|hh signalling pathway|Sonic hedgehog signaling pathway|hh signaling pathway|Shh signaling pathway|hedgehog signaling pathway A series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened. GO:0046875 ephrin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046875 GPI-linked ephrin|transmembrane ephrin|Eph receptor binding|ephrin Interacting selectively and non-covalently with an ephrin receptor. GO:1900941 regulation of (Z)-nonadeca-1,14-diene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900941 regulation of (Z)-nonadeca-1,14-diene biosynthesis|regulation of (Z)-nonadeca-1,14-diene anabolism|regulation of (Z)-nonadeca-1,14-diene synthesis|regulation of (Z)-nonadeca-1,14-diene formation Any process that modulates the frequency, rate or extent of (Z)-nonadeca-1,14-diene biosynthetic process. GO:0007223 Wnt signaling pathway, calcium modulating pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007223 non-canonical Wnt signaling pathway|Wnt receptor signaling pathway, calcium modulating pathway|Wnt-activated signaling pathway, calcium modulating pathway|frizzled-2 signaling pathway|frizzled-2 signalling pathway The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC). GO:1900940 positive regulation of (Z)-nonadeca-1,14-diene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900940 up regulation of (Z)-nonadeca-1,14-diene metabolic process|positive regulation of (Z)-nonadeca-1,14-diene metabolism|activation of (Z)-nonadeca-1,14-diene metabolic process|up regulation of (Z)-nonadeca-1,14-diene metabolism|upregulation of (Z)-nonadeca-1,14-diene metabolism|up-regulation of (Z)-nonadeca-1,14-diene metabolic process|up-regulation of (Z)-nonadeca-1,14-diene metabolism|upregulation of (Z)-nonadeca-1,14-diene metabolic process|activation of (Z)-nonadeca-1,14-diene metabolism Any process that activates or increases the frequency, rate or extent of (Z)-nonadeca-1,14-diene metabolic process. GO:0046874 quinolinate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046874 quinolinate metabolism The chemical reactions and pathways involving quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid. GO:0007222 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007222 GO:0007221 positive regulation of transcription of Notch receptor target biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007221 N receptor target transcription factor activation|Notch receptor target transcription factor activation The activation of transcription of specific genes as a result of Notch signaling, mediated by the Notch intracellular domain. GO:0046873 metal ion transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046873 high affinity metal ion uptake transporter activity|heavy metal-exporting ATPase activity|heavy metal ion transporter activity|low affinity metal ion uptake transporter activity|heavy metal ion porter activity|heavy metal ion:hydrogen symporter activity Enables the transfer of metal ions from one side of a membrane to the other. GO:0046872 metal ion binding biolink:MolecularActivity go-plus goslim_flybase_ribbon|goslim_agr|goslim_drosophila|goslim_metagenomics http://purl.obolibrary.org/obo/GO_0046872 heavy metal binding|metal binding Interacting selectively and non-covalently with any metal ion. GO:0007220 Notch receptor processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007220 N receptor processing The series of successive proteolytic cleavages of the Notch protein, which result in an active form of the receptor. GO:0046871 N-acetylgalactosamine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046871 N-acetylgalactosamine lectin Interacting selectively and non-covalently with N-acetylgalactosamine, 2-acetamido-2-deoxygalactopyranose, the n-acetyl derivative of galactosamine. GO:0071809 regulation of fever generation by regulation of prostaglandin biosynthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071809 Any process that modulates the rate or extent of fever generation via regulation of the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin. GO:0046870 cadmium ion binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046870 cadmium binding|copper/cadmium binding Interacting selectively and non-covalently with cadmium (Cd) ions. GO:0071819 DUBm complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071819 deubiquitinating module|SAGA DUBm complex|deubiquitination module A protein complex that forms part of SAGA-type complexes SAGA and SLIK, and mediates deubiquitination of histone H2B. In S. cerevisiae, the DUBm consists of the proteins Ubp8p, Sgf11p, Sus1p, and Sgf73p. GO:0071818 BAT3 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071818 BAG6-UBL4A-TRC35 complex|BAT3-TRC35-UBL4A complex|Bag6 complex A protein complex consisting of BAT3 (BAG6) and its cofactors. In mammals these cofactors are TRC35 (GET4) and UBL4A. It facilitates tail-anchored protein capture by ASNA1/TRC4 and also chaperones polypeptides from the endoplasmic reticulum retrotranslocation machinery to the proteasome, maintaining the solubility of substrates to improve ER-associated protein degradation (ERAD). GO:0071817 MMXD complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071817 MMS19-MIP18-XPD complex A protein complex that contains the proteins MMS19, MIP18 and XPD, localizes to mitotic spindle during mitosis, and is required for proper chromosome segregation. GO:0071816 tail-anchored membrane protein insertion into ER membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071816 protein insertion of tail-anchored membrane proteins into ER membrane|type II transmembrane protein insertion into ER membrane|tail-anchored membrane protein insertion into endoplasmic reticulum membrane A process of protein insertion into the endoplasmic reticulum (ER) membrane in which a tail-anchored (TA) transmembrane protein is incorporated into an endoplasmic reticulum (ER) membrane. TA transmembrane protein, also named type II transmembrane proteins, contain a single C- terminal transmembrane region. GO:0071815 intermediate-density lipoprotein particle binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071815 IDL binding|intermediate-density lipoprotein binding Interacting selectively and non-covalently with a intermediate-density lipoprotein particle, a triglyceride-rich lipoprotein particle that typically contains APOB100, APOE and APOCs and has a density of 1.006-1.019 g/ml and a diameter of between 25-30 nm. GO:0071814 protein-lipid complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071814 Interacting selectively and non-covalently with a protein-lipid complex, any macromolecular complex that contains both protein and lipid molecules. GO:0046879 hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046879 The regulated release of hormones, substances with a specific regulatory effect on a particular organ or group of cells. GO:0071813 lipoprotein particle binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071813 plasma lipoprotein binding|lipoprotein binding|plasma lipoprotein particle binding Interacting selectively and non-covalently with a lipoprotein particle. A lipoprotein particle, also known as a lipoprotein, is a clathrate complex consisting of a lipid enwrapped in a protein host without covalent binding in such a way that the complex has a hydrophilic outer surface consisting of all the protein and the polar ends of any phospholipids. GO:0046878 positive regulation of saliva secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046878 upregulation of saliva secretion|stimulation of saliva secretion|up-regulation of saliva secretion|activation of saliva secretion|up regulation of saliva secretion Any process that activates or increases the frequency, rate or extent of the regulated release of saliva. GO:0071812 positive regulation of fever generation by positive regulation of prostaglandin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071812 Any process that increases the rate or extent of fever generation via positive regulation of the frequency, rate or extent of the regulated release of a prostaglandin from a cell. GO:0071811 positive regulation of fever generation by positive regulation of prostaglandin biosynthesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071811 Any process that increases the rate or extent of fever generation via positive regulation of the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin. GO:0022844 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0022844 GO:0071810 regulation of fever generation by regulation of prostaglandin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071810 Any process that modulates the rate or extent of fever generation via regulation of the frequency, rate or extent of the regulated release of a prostaglandin from a cell. GO:0022843 voltage-gated cation channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022843 Reactome:R-HSA-6788999|Reactome:R-HSA-2534378 Enables the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. GO:0022848 acetylcholine-gated cation-selective channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022848 nicotinergic acetylcholine receptor activity|ionotropic acetylcholine receptor activity|acetylcholine-activated cation-selective channel activity|nicotinic acetylcholine-activated cation-selective channel activity|acetylcholine-gated cation channel activity|nAChR Selectively enables the transmembrane transfer of a cation by a channel that opens upon binding acetylcholine. GO:0022849 glutamate-gated calcium ion channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022849 Enables the transmembrane transfer of a calcium ion by a channel that opens when glutamate has been bound by the channel complex or one of its constituent parts. GO:1900958 positive regulation of 17-methylnonadec-1-ene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900958 up-regulation of 17-methylnonadec-1-ene biosynthetic process|up-regulation of 17-methylnonadec-1-ene biosynthesis|activation of 17-methylnonadec-1-ene formation|up regulation of 17-methylnonadec-1-ene anabolism|positive regulation of 17-methylnonadec-1-ene synthesis|up regulation of 17-methylnonadec-1-ene synthesis|positive regulation of 17-methylnonadec-1-ene formation|up regulation of 17-methylnonadec-1-ene formation|upregulation of 17-methylnonadec-1-ene biosynthesis|upregulation of 17-methylnonadec-1-ene biosynthetic process|upregulation of 17-methylnonadec-1-ene anabolism|upregulation of 17-methylnonadec-1-ene synthesis|upregulation of 17-methylnonadec-1-ene formation|up regulation of 17-methylnonadec-1-ene biosynthesis|up regulation of 17-methylnonadec-1-ene biosynthetic process|up-regulation of 17-methylnonadec-1-ene anabolism|positive regulation of 17-methylnonadec-1-ene biosynthesis|activation of 17-methylnonadec-1-ene biosynthetic process|up-regulation of 17-methylnonadec-1-ene synthesis|activation of 17-methylnonadec-1-ene anabolism|activation of 17-methylnonadec-1-ene biosynthesis|up-regulation of 17-methylnonadec-1-ene formation|activation of 17-methylnonadec-1-ene synthesis|positive regulation of 17-methylnonadec-1-ene anabolism Any process that activates or increases the frequency, rate or extent of 17-methylnonadec-1-ene biosynthetic process. GO:0046880 regulation of follicle-stimulating hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046880 regulation of FSH secretion|regulation of follicle stimulating hormone secretion Any process that modulates the frequency, rate or extent of the regulated release of follicle-stimulating hormone. GO:1900957 negative regulation of 17-methylnonadec-1-ene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900957 negative regulation of 17-methylnonadec-1-ene formation|down-regulation of 17-methylnonadec-1-ene formation|downregulation of 17-methylnonadec-1-ene anabolism|inhibition of 17-methylnonadec-1-ene biosynthesis|down regulation of 17-methylnonadec-1-ene anabolism|downregulation of 17-methylnonadec-1-ene synthesis|downregulation of 17-methylnonadec-1-ene formation|down regulation of 17-methylnonadec-1-ene biosynthetic process|down regulation of 17-methylnonadec-1-ene biosynthesis|down regulation of 17-methylnonadec-1-ene synthesis|down regulation of 17-methylnonadec-1-ene formation|inhibition of 17-methylnonadec-1-ene anabolism|downregulation of 17-methylnonadec-1-ene biosynthesis|downregulation of 17-methylnonadec-1-ene biosynthetic process|inhibition of 17-methylnonadec-1-ene synthesis|inhibition of 17-methylnonadec-1-ene formation|down-regulation of 17-methylnonadec-1-ene biosynthetic process|negative regulation of 17-methylnonadec-1-ene biosynthesis|down-regulation of 17-methylnonadec-1-ene biosynthesis|negative regulation of 17-methylnonadec-1-ene anabolism|down-regulation of 17-methylnonadec-1-ene anabolism|negative regulation of 17-methylnonadec-1-ene synthesis|down-regulation of 17-methylnonadec-1-ene synthesis|inhibition of 17-methylnonadec-1-ene biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of 17-methylnonadec-1-ene biosynthetic process. CHEBI:45021 palmitoyl group biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_45021 CHEBI:21054 mannonic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21054 GO:1900959 regulation of 17-methylnonadec-1-ene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900959 regulation of 17-methylnonadec-1-ene metabolism Any process that modulates the frequency, rate or extent of 17-methylnonadec-1-ene metabolic process. GO:1900954 negative regulation of 18-methylnonadec-1-ene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900954 inhibition of 18-methylnonadec-1-ene metabolism|down-regulation of 18-methylnonadec-1-ene metabolic process|down regulation of 18-methylnonadec-1-ene metabolism|downregulation of 18-methylnonadec-1-ene metabolism|downregulation of 18-methylnonadec-1-ene metabolic process|down regulation of 18-methylnonadec-1-ene metabolic process|down-regulation of 18-methylnonadec-1-ene metabolism|negative regulation of 18-methylnonadec-1-ene metabolism|inhibition of 18-methylnonadec-1-ene metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of 18-methylnonadec-1-ene metabolic process. GO:1900953 regulation of 18-methylnonadec-1-ene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900953 regulation of 18-methylnonadec-1-ene metabolism Any process that modulates the frequency, rate or extent of 18-methylnonadec-1-ene metabolic process. GO:1900956 regulation of 17-methylnonadec-1-ene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900956 regulation of 17-methylnonadec-1-ene anabolism|regulation of 17-methylnonadec-1-ene synthesis|regulation of 17-methylnonadec-1-ene formation|regulation of 17-methylnonadec-1-ene biosynthesis Any process that modulates the frequency, rate or extent of 17-methylnonadec-1-ene biosynthetic process. GO:0022831 narrow pore, gated channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022831 Wikipedia:Ion_channels ion channels Enables the transport of a solute across a membrane via a narrow pore channel that opens in response to a particular stimulus. GO:1900955 positive regulation of 18-methylnonadec-1-ene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900955 up-regulation of 18-methylnonadec-1-ene metabolism|up-regulation of 18-methylnonadec-1-ene metabolic process|activation of 18-methylnonadec-1-ene metabolic process|upregulation of 18-methylnonadec-1-ene metabolism|up regulation of 18-methylnonadec-1-ene metabolic process|up regulation of 18-methylnonadec-1-ene metabolism|positive regulation of 18-methylnonadec-1-ene metabolism|activation of 18-methylnonadec-1-ene metabolism|upregulation of 18-methylnonadec-1-ene metabolic process Any process that activates or increases the frequency, rate or extent of 18-methylnonadec-1-ene metabolic process. GO:0046888 negative regulation of hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046888 down regulation of hormone secretion|downregulation of hormone secretion|down-regulation of hormone secretion|inhibition of hormone secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a hormone from a cell. GO:1900950 regulation of 18-methylnonadec-1-ene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900950 regulation of 18-methylnonadec-1-ene anabolism|regulation of 18-methylnonadec-1-ene synthesis|regulation of 18-methylnonadec-1-ene formation|regulation of 18-methylnonadec-1-ene biosynthesis Any process that modulates the frequency, rate or extent of 18-methylnonadec-1-ene biosynthetic process. GO:0046887 positive regulation of hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046887 up regulation of hormone secretion|activation of hormone secretion|stimulation of hormone secretion|up-regulation of hormone secretion|upregulation of hormone secretion Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell. GO:1900952 positive regulation of 18-methylnonadec-1-ene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900952 up regulation of 18-methylnonadec-1-ene synthesis|positive regulation of 18-methylnonadec-1-ene formation|up regulation of 18-methylnonadec-1-ene formation|upregulation of 18-methylnonadec-1-ene biosynthetic process|upregulation of 18-methylnonadec-1-ene anabolism|upregulation of 18-methylnonadec-1-ene biosynthesis|upregulation of 18-methylnonadec-1-ene synthesis|upregulation of 18-methylnonadec-1-ene formation|up-regulation of 18-methylnonadec-1-ene anabolism|up regulation of 18-methylnonadec-1-ene biosynthesis|up regulation of 18-methylnonadec-1-ene biosynthetic process|positive regulation of 18-methylnonadec-1-ene biosynthesis|activation of 18-methylnonadec-1-ene biosynthetic process|up-regulation of 18-methylnonadec-1-ene synthesis|activation of 18-methylnonadec-1-ene anabolism|up-regulation of 18-methylnonadec-1-ene formation|activation of 18-methylnonadec-1-ene biosynthesis|activation of 18-methylnonadec-1-ene synthesis|positive regulation of 18-methylnonadec-1-ene anabolism|activation of 18-methylnonadec-1-ene formation|up regulation of 18-methylnonadec-1-ene anabolism|up-regulation of 18-methylnonadec-1-ene biosynthetic process|up-regulation of 18-methylnonadec-1-ene biosynthesis|positive regulation of 18-methylnonadec-1-ene synthesis Any process that activates or increases the frequency, rate or extent of 18-methylnonadec-1-ene biosynthetic process. GO:0046886 positive regulation of hormone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046886 positive regulation of hormone biosynthesis|positive regulation of hormone anabolism|up regulation of hormone biosynthetic process|positive regulation of hormone synthesis|positive regulation of hormone formation|upregulation of hormone biosynthetic process|stimulation of hormone biosynthetic process|up-regulation of hormone biosynthetic process|activation of hormone biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones. GO:1900951 negative regulation of 18-methylnonadec-1-ene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900951 downregulation of 18-methylnonadec-1-ene anabolism|inhibition of 18-methylnonadec-1-ene biosynthesis|down regulation of 18-methylnonadec-1-ene anabolism|downregulation of 18-methylnonadec-1-ene synthesis|downregulation of 18-methylnonadec-1-ene formation|down regulation of 18-methylnonadec-1-ene synthesis|down regulation of 18-methylnonadec-1-ene biosynthesis|down regulation of 18-methylnonadec-1-ene biosynthetic process|down regulation of 18-methylnonadec-1-ene formation|inhibition of 18-methylnonadec-1-ene anabolism|downregulation of 18-methylnonadec-1-ene biosynthetic process|downregulation of 18-methylnonadec-1-ene biosynthesis|inhibition of 18-methylnonadec-1-ene synthesis|inhibition of 18-methylnonadec-1-ene formation|down-regulation of 18-methylnonadec-1-ene biosynthetic process|down-regulation of 18-methylnonadec-1-ene anabolism|negative regulation of 18-methylnonadec-1-ene anabolism|down-regulation of 18-methylnonadec-1-ene biosynthesis|negative regulation of 18-methylnonadec-1-ene biosynthesis|down-regulation of 18-methylnonadec-1-ene synthesis|negative regulation of 18-methylnonadec-1-ene synthesis|inhibition of 18-methylnonadec-1-ene biosynthetic process|negative regulation of 18-methylnonadec-1-ene formation|down-regulation of 18-methylnonadec-1-ene formation Any process that stops, prevents or reduces the frequency, rate or extent of 18-methylnonadec-1-ene biosynthetic process. GO:0046885 regulation of hormone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046885 regulation of hormone anabolism|regulation of hormone synthesis|regulation of hormone formation|regulation of hormone biosynthesis Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones. GO:0046884 follicle-stimulating hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046884 follitropin secretion|FSH secretion|follicle stimulating hormone secretion The regulated release of follicle-stimulating hormone, a gonadotropic glycoprotein hormone secreted by the anterior pituitary. GO:0046883 regulation of hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046883 Any process that modulates the frequency, rate or extent of the regulated release of a hormone from a cell. GO:0046882 negative regulation of follicle-stimulating hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046882 down-regulation of follicle-stimulating hormone secretion|downregulation of follicle-stimulating hormone secretion|down regulation of follicle-stimulating hormone secretion|inhibition of follicle-stimulating hormone secretion|negative regulation of follicle stimulating hormone secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of follicle-stimulating hormone. GO:0046881 positive regulation of follicle-stimulating hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046881 stimulation of follicle-stimulating hormone secretion|positive regulation of follicle stimulating hormone secretion|activation of follicle-stimulating hormone secretion|up-regulation of follicle-stimulating hormone secretion|up regulation of follicle-stimulating hormone secretion|upregulation of follicle-stimulating hormone secretion Any process that activates or increases the frequency, rate or extent of the regulated release of follicle-stimulating hormone. CHEBI:35695 dicarboxylic acid monoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35695 UBERON:2000315 asteriscus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_2000315 lagenar otolith|lagenolith GO:0071849 G1 cell cycle arrest in response to nitrogen starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071849 The process in which the cell cycle is halted during G1 phase, as a result of deprivation of nitrogen. CHEBI:35697 trans-cinnamic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35697 GO:0071848 positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071848 positive regulation of ERK1 and ERK2 cascade via RANKL-mediated signaling|positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signalling Any TNFSF11-mediated signaling process that increases the rate, frequency, or extent of the ERK1 and ERK2 cascade. GO:0071847 TNFSF11-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071847 RANKL-mediated signaling pathway|TNFSF11-mediated signalling pathway|tumor necrosis factor superfamily member 11-mediated signaling pathway|receptor activator of nuclear factor kappa-B ligand signaling pathway|TNF-related activation-induced cytokine-mediated signaling pathway A series of molecular signals initiated by the binding of tumor necrosis factor ligand superfamily member 11 (TNFSF11) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0071846 actin filament debranching biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071846 An actin filament severing process that results in the removal of actin filament branches specifically at the branch points. GO:0046889 positive regulation of lipid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046889 positive regulation of lipogenesis|positive regulation of lipid synthesis|positive regulation of lipid formation|stimulation of lipid biosynthetic process|up-regulation of lipid biosynthetic process|activation of lipid biosynthetic process|positive regulation of lipid biosynthesis|up regulation of lipid biosynthetic process|positive regulation of lipid anabolism|upregulation of lipid biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids. GO:0071845 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0071845 GO:0022833 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0022833 GO:0071844 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0071844 CHEBI:69080 methyl linoleate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_69080 GO:0022832 voltage-gated channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022832 Enables the transmembrane transfer of a solute by a channel whose open state is dependent on the voltage across the membrane in which it is embedded. GO:0071843 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0071843 GO:0022835 transmitter-gated channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022835 neurotransmitter-gated channel activity|extracellular substance gated channel activity Enables the transmembrane transfer of a solute by a channel that opens when a specific neurotransmitter has been bound by the channel complex or one of its constituent parts. CHEBI:35690 cyclobutane-1,1-dicarboxylate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35690 GO:0071842 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0071842 GO:0022834 ligand-gated channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022834 Enables the transmembrane transfer of a solute by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts. GO:0071841 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0071841 CHEBI:69081 1-monopalmitoylglycerol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_69081 GO:0071840 cellular component organization or biogenesis biolink:BiologicalProcess go-plus goslim_metagenomics|goslim_flybase_ribbon http://purl.obolibrary.org/obo/GO_0071840 cellular component organisation or biogenesis|cellular component organisation or biogenesis at cellular level|cellular component organization or biogenesis at cellular level A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component. CHEBI:35692 dicarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35692 GO:0022836 gated channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022836 Enables the transmembrane transfer of a solute by a channel that opens in response to a specific stimulus. CHEBI:35691 cyclobutane-1,1-dicarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35691 GO:0022839 ion gated channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022839 Enables the transmembrane transfer of a solute by a channel that opens in response to a specific ion stimulus. CHEBI:35694 cyclobutane-1,1-dicarboxylate(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35694 GO:0022838 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0022838 CHEBI:35693 dicarboxylic acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35693 GO:1900969 negative regulation of sarcinapterin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900969 down-regulation of sarcinapterin metabolic process|negative regulation of sarcinapterin metabolism|down-regulation of sarcinapterin metabolism|inhibition of sarcinapterin metabolic process|downregulation of sarcinapterin metabolism|down regulation of sarcinapterin metabolism|down regulation of sarcinapterin metabolic process|downregulation of sarcinapterin metabolic process|inhibition of sarcinapterin metabolism Any process that stops, prevents or reduces the frequency, rate or extent of sarcinapterin metabolic process. GO:0046891 peptidyl-cysteine S-carbamoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046891 RESID:AA0332 The carbamoylation of peptidyl-cysteine to form peptidyl-S-carbamoyl-L-cysteine. GO:0046890 regulation of lipid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046890 regulation of lipid anabolism|regulation of lipogenesis|regulation of lipid biosynthesis|regulation of lipid synthesis|regulation of lipid formation Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids. GO:1900968 regulation of sarcinapterin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900968 regulation of sarcinapterin metabolism Any process that modulates the frequency, rate or extent of sarcinapterin metabolic process. GO:0007209 phospholipase C-activating tachykinin receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007209 activation of phospholipase C activity by tachykinin receptor signaling pathway|activation of phospholipase C activity by tachykinin receptor signalling pathway|tachykinin receptor, phospholipase C activating pathway The series of molecular signals generated as a consequence of a tachykinin receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG). GO:0007208 phospholipase C-activating serotonin receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007208 activation of phospholipase C activity by serotonin receptor signalling pathway|serotonin receptor, phospholipase C activating pathway|activation of phospholipase C activity by serotonin receptor signaling pathway The series of molecular signals generated as a consequence of a serotonin receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG). GO:0007207 phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007207 muscarinic acetylcholine receptor, phospholipase C activating pathway|activation of phospholipase C activity by G-protein coupled acetylcholine receptor signaling pathway|activation of phospholipase C activity by muscarinic acetylcholine receptor signaling pathway|phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway|muscarinic receptor signaling pathway via activation of PLC|activation of phospholipase C activity by muscarinic acetylcholine receptor signalling pathway The series of molecular signals generated as a consequence of a G protein-coupled acetylcholine receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG). GO:1900965 regulation of methanophenazine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900965 regulation of methanophenazine metabolism Any process that modulates the frequency, rate or extent of methanophenazine metabolic process. GO:1900964 positive regulation of methanophenazine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900964 up-regulation of methanophenazine biosynthesis|up-regulation of methanophenazine biosynthetic process|upregulation of methanophenazine anabolism|upregulation of methanophenazine synthesis|upregulation of methanophenazine formation|upregulation of methanophenazine biosynthesis|upregulation of methanophenazine biosynthetic process|up-regulation of methanophenazine anabolism|up-regulation of methanophenazine synthesis|activation of methanophenazine anabolism|up-regulation of methanophenazine formation|up regulation of methanophenazine biosynthesis|up regulation of methanophenazine biosynthetic process|activation of methanophenazine synthesis|positive regulation of methanophenazine anabolism|activation of methanophenazine biosynthetic process|positive regulation of methanophenazine biosynthesis|activation of methanophenazine formation|up regulation of methanophenazine anabolism|positive regulation of methanophenazine synthesis|activation of methanophenazine biosynthesis|up regulation of methanophenazine synthesis|positive regulation of methanophenazine formation|up regulation of methanophenazine formation Any process that activates or increases the frequency, rate or extent of methanophenazine biosynthetic process. GO:0007206 phospholipase C-activating G protein-coupled glutamate receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway|activation of phospholipase C activity by metabotropic glutamate receptor signalling pathway|activation of phospholipase C activity by G-protein coupled glutamate receptor signaling pathway|metabotropic glutamate receptor, phospholipase C activating pathway|activation of phospholipase C activity by metabotropic glutamate receptor signaling pathway The series of molecular signals generated as a consequence of a G protein-coupled glutamate receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG). GO:1900967 positive regulation of methanophenazine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900967 activation of methanophenazine metabolism|up-regulation of methanophenazine metabolic process|activation of methanophenazine metabolic process|up-regulation of methanophenazine metabolism|up regulation of methanophenazine metabolic process|upregulation of methanophenazine metabolism|upregulation of methanophenazine metabolic process|up regulation of methanophenazine metabolism|positive regulation of methanophenazine metabolism Any process that activates or increases the frequency, rate or extent of methanophenazine metabolic process. GO:0007205 protein kinase C-activating G protein-coupled receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007205 activation of protein kinase C activity by G-protein coupled receptor protein signalling pathway|activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway|protein kinase C-activating G-protein coupled receptor signaling pathway The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of protein kinase C (PKC). PKC is activated by second messengers including diacylglycerol (DAG). GO:0022820 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0022820 GO:0007204 positive regulation of cytosolic calcium ion concentration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007204 cytoplasmic calcium ion concentration elevation|elevation of cytoplasmic calcium ion concentration|cytosolic calcium ion concentration elevation|elevation of cytosolic calcium ion concentration|elevation of calcium ion concentration in cytoplasm|elevation of calcium ion concentration in cytosol Any process that increases the concentration of calcium ions in the cytosol. GO:1900966 negative regulation of methanophenazine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900966 down-regulation of methanophenazine metabolic process|inhibition of methanophenazine metabolism|downregulation of methanophenazine metabolic process|down regulation of methanophenazine metabolism|down regulation of methanophenazine metabolic process|downregulation of methanophenazine metabolism|inhibition of methanophenazine metabolic process|down-regulation of methanophenazine metabolism|negative regulation of methanophenazine metabolism Any process that stops, prevents or reduces the frequency, rate or extent of methanophenazine metabolic process. GO:1900961 positive regulation of 17-methylnonadec-1-ene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900961 up regulation of 17-methylnonadec-1-ene metabolic process|up regulation of 17-methylnonadec-1-ene metabolism|positive regulation of 17-methylnonadec-1-ene metabolism|activation of 17-methylnonadec-1-ene metabolism|upregulation of 17-methylnonadec-1-ene metabolic process|up-regulation of 17-methylnonadec-1-ene metabolism|up-regulation of 17-methylnonadec-1-ene metabolic process|activation of 17-methylnonadec-1-ene metabolic process|upregulation of 17-methylnonadec-1-ene metabolism Any process that activates or increases the frequency, rate or extent of 17-methylnonadec-1-ene metabolic process. GO:0007203 obsolete phosphatidylinositol-4,5-bisphosphate hydrolysis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007203 phosphatidylinositol-4,5-bisphosphate hydrolysis OBSOLETE. (Was not defined before being made obsolete). GO:0046899 nucleoside triphosphate adenylate kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046899 RHEA:13749|Reactome:R-HSA-1008248|EC:2.7.4.10|MetaCyc:2.7.4.10-RXN guanosine triphosphate-adenylate kinase|nucleoside triphosphate-adenosine monophosphate transphosphorylase activity|isozyme 3 of adenylate kinase activity|GTP:AMP phosphotransferase|nucleoside-triphosphate-adenylate kinase activity|nucleoside-triphosphate:AMP phosphotransferase activity Catalysis of the reaction: nucleoside triphosphate + AMP = nucleoside diphosphate + ADP. GO:1900960 negative regulation of 17-methylnonadec-1-ene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900960 downregulation of 17-methylnonadec-1-ene metabolic process|negative regulation of 17-methylnonadec-1-ene metabolism|down-regulation of 17-methylnonadec-1-ene metabolism|down regulation of 17-methylnonadec-1-ene metabolic process|inhibition of 17-methylnonadec-1-ene metabolic process|inhibition of 17-methylnonadec-1-ene metabolism|down regulation of 17-methylnonadec-1-ene metabolism|down-regulation of 17-methylnonadec-1-ene metabolic process|downregulation of 17-methylnonadec-1-ene metabolism Any process that stops, prevents or reduces the frequency, rate or extent of 17-methylnonadec-1-ene metabolic process. GO:0046898 response to cycloheximide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046898 response to actidione Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloheximide stimulus. Cycloheximide (actidione) is an antibiotic produced by some Streptomyces species which interferes with protein synthesis in eukaryotes. GO:0007202 activation of phospholipase C activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007202 phospholipase C activation The initiation of the activity of the inactive enzyme phospolipase C as the result of a series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand. GO:1900963 negative regulation of methanophenazine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900963 inhibition of methanophenazine biosynthetic process|downregulation of methanophenazine formation|down regulation of methanophenazine synthesis|inhibition of methanophenazine anabolism|down regulation of methanophenazine formation|inhibition of methanophenazine biosynthesis|inhibition of methanophenazine synthesis|down regulation of methanophenazine biosynthetic process|inhibition of methanophenazine formation|down regulation of methanophenazine biosynthesis|downregulation of methanophenazine biosynthesis|downregulation of methanophenazine biosynthetic process|down-regulation of methanophenazine anabolism|negative regulation of methanophenazine anabolism|down-regulation of methanophenazine synthesis|negative regulation of methanophenazine synthesis|down-regulation of methanophenazine formation|negative regulation of methanophenazine formation|down-regulation of methanophenazine biosynthesis|down-regulation of methanophenazine biosynthetic process|negative regulation of methanophenazine biosynthesis|downregulation of methanophenazine anabolism|down regulation of methanophenazine anabolism|downregulation of methanophenazine synthesis Any process that stops, prevents or reduces the frequency, rate or extent of methanophenazine biosynthetic process. GO:0046897 N-terminal peptidyl-tyrosine methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046897 RESID:AA0338 The methylation of the N-terminal tyrosine of proteins to form the derivative N-methyl-L-tyrosine. GO:0007201 obsolete G-protein dissociation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007201 G-protein dissociation OBSOLETE. (Was not defined before being made obsolete). CHEBI:21060 mannose phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21060 GO:1900962 regulation of methanophenazine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900962 regulation of methanophenazine synthesis|regulation of methanophenazine formation|regulation of methanophenazine biosynthesis|regulation of methanophenazine anabolism Any process that modulates the frequency, rate or extent of methanophenazine biosynthetic process. GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007200 G-protein coupled receptor signaling pathway coupled to IP3 second messenger|G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|phospholipase C-activating dopamine receptor signaling pathway|phospholipase C-activating G-protein coupled receptor signaling pathway|PLC-activating GPCR signaling pathway The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent increase in the concentration of inositol trisphosphate (IP3) and diacylglycerol (DAG). GO:0046896 N-terminal peptidyl-leucine methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046896 RESID:AA0337 The methylation of the N-terminal leucine of proteins to form the derivative N-methyl-L-leucine. GO:0046895 N-terminal peptidyl-isoleucine methylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046895 RESID:AA0336 The methylation of the N-terminal isoleucine of proteins to form the derivative N-methyl-L-isoleucine. GO:0046894 obsolete enzyme active site formation via S-amidino-L-cysteine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046894 OBSOLETE. Active site formation via the transient amidinylation of peptidyl-cysteine to form peptidyl-S-amidino-L-cysteine. GO:0046893 iron incorporation into hydrogenase diiron subcluster via L-cysteine ligation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046893 RESID:AA0334 The incorporation of iron into an L-cysteinyl diiron subcluster, found in Fe-hydrogenase. CHEBI:45013 2-phospho-L-lactic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_45013 GO:0046892 peptidyl-S-carbamoyl-L-cysteine dehydration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046892 RESID:AA0333 formation of peptidyl-serine thiocyanate ester|formation of peptidyl-S-cyanocysteine The dehydration of peptidyl-S-carbamoyl-L-cysteine to form peptidyl-S-cyano-L-cysteine. GO:0140096 catalytic activity, acting on a protein biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140096 Catalytic activity that acts to modify a protein. GO:0022829 wide pore channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022829 non-gated, wide pore channel activity|gap junction activity Enables the transport of a solute across a membrane via a large pore, un-gated channel. Examples include gap junctions, which transport substances from one cell to another; and porins which transport substances in and out of bacteria, mitochondria and chloroplasts. CHEBI:59651 arseno-mycothiol biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59651 GO:0071839 apoptotic process in bone marrow cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071839 programmed cell death, bone marrow cells|killing of bone marrow cells|apoptotic process in bone marrow cell|programmed cell death of bone marrow cells by apoptosis|apoptosis in bone marrow|bone marrow cell apoptosis|bone marrow cell programmed cell death by apoptosis The apoptotic process in cells in the bone marrow. GO:0140098 catalytic activity, acting on RNA biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140098 Catalytic activity that acts to modify RNA. CHEBI:59650 amino fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59650 GO:0071838 cell proliferation in bone marrow biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071838 bone marrow cell proliferation The multiplication or reproduction of cells, resulting in the expansion of a cell population in the bone marrow. GO:0140097 catalytic activity, acting on DNA biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140097 Catalytic activity that acts to modify DNA. GO:0071837 HMG box domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071837 Interacting selectively and non-covalently with an HMG box domain, a protein domain that consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin. GO:0071836 nectar secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071836 nectar production The controlled release of a nectar by a cell or a tissue. Nectar is a fluid secreted by many angiosperms to promote pollination by providing a reward to pollinators. Nectar may also deter certain organisms from visiting or play other biological roles. Nectar is a complex solution that may include the following types of compounds: sugars, amino acids, organic acids, alkaloids, flavonoids, glycosides, vitamins, phenolics, metal ions, oils, free fatty acids, and proteins. GO:0071835 mating pheromone secretion involved in regulation of conjugation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071835 mating-type pheromone secretion involved in conjugation The regulated release of a mating pheromone, a peptide hormone that induces a behavioral or physiological response(s) from a responding organism or cell, that regulates the union or introduction of genetic information from compatible mating types that results in a genetically different individual. Conjugation requires direct cellular contact between the organisms. GO:0071834 mating pheromone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071834 mating-type pheromone secretion The regulated release of a mating pheromone, a peptide hormone that induces a behavioral or physiological response(s) from a responding organism or cell, that contributes to a process of sexual reproduction. GO:0071833 peptide pheromone export involved in positive regulation of conjugation with cellular fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071833 The directed movement of a peptide pheromone out of a cell by a secretion or export pathway used solely for the export of peptide pheromones that contributes to a conjugation process that results in the union of cellular and genetic information from compatible mating types. GO:0071832 peptide pheromone export involved in regulation of conjugation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071832 The directed movement of a peptide pheromone out of a cell by a secretion or export pathway used solely for the export of peptide pheromones that contributes to the union or introduction of genetic information from compatible mating types that results in a genetically different individual. Conjugation requires direct cellular contact between the organisms. GO:0022821 potassium ion antiporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022821 Catalysis of the active transport of a potassium ion across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. GO:0071831 intermediate-density lipoprotein particle clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071831 IDL clearance The process in which a intermediate-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. GO:0140090 membrane curvature sensor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140090 Preferential binding of proteins on curved membranes. The binding to curved membranes by insertion (aka wedging) to curved membranes is mediated by both the hydrophobic and hydrophilic faces of the helix of membrane curvature sensing (MCS) proteins. GO:0022824 transmitter-gated ion channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022824 ionotropic neurotransmitter receptor activity Enables the transmembrane transfer of an ion by a channel that opens when a specific neurotransmitter has been bound by the channel complex or one of its constituent parts. GO:0071830 triglyceride-rich lipoprotein particle clearance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071830 The process in which a triglyceride-rich lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. GO:0140092 bBAF complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140092 brain-specific BAF complex|brain-specific SWI/SNF complex A brain-specific SWI/SNF-type complex that contains eight or nine proteins, including both conserved (core) and nonconserved components; contains the ATPase product of either the SMARCA4/BAF190A/BRG1 gene, the mammalian ortholog of the yeast SNF2 gene, or the SMARCA2/BAF190B/BRM gene, the mammalian ortholog of the Drosophila brm (brahma) gene, or an ortholog of either of these genes. Compared to the neuron-specific nBAF complex (GO:0071565) it does not contain DPF1, DPF3 or SMARCC1 or their orthologs. May contain PB1/BAF180. GO:0140091 mBAF complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140091 muscle-type BAF complex|muscle-type SWI/SNF complex|muscle-specific BAF complex|muscle-specific SWI/SNF complex A muscle cell-specific SWI/SNF-type complex that contains eight to fourteen proteins, including both conserved (core) and nonconserved components; contains the ATPase product of either the SMARCA4/BAF190A/BRG1 gene, the mammalian ortholog of the yeast SNF2 gene, or the SMARCA2/BAF190B/BRM gene, the mammalian ortholog of the Drosophila brm (brahma) gene, or an ortholog of either of these genes, and the muscle-specific product of the DPF3/BAF45C gene or an ortholog thereof. GO:0022825 obsolete copper-exporting ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022825 copper-exporting ATPase activity OBSOLETE. (Was not defined before being made obsolete). CHEBI:59655 arseno-mycothiol(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59655 GO:0022828 phosphorylation-gated channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022828 Enables the transmembrane transfer of a solute by a channel that opens in response to phosphorylation of one of its constituent parts. GO:0140093 esBAF complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140093 embryonic stem cell-specific BAF complex|embryonic stem cell-specific SWI/SNF complex An embryonic stem cell-specific SWI/SNF-type complex that contains eight or nine proteins, including both conserved (core) and nonconserved components; contains the ATPase product of either the SMARCA4/BAF190A/BRG1 gene, the mammalian ortholog of the yeast SNF2 gene, or an ortholog thereof. Compared to many other BAF complexes never contains ACTL6B/BAF53B, ARID1B/BAF250B, SMARCA2/BRM, SMARCC2/BAF170 or SMARCD3/BAF60C but contains PHF10/BAF45A, DPF2/BAF45D and possibly one of BCL7A/B/C. CHEBI:59653 arseno-mycothiol(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59653 GO:1900979 positive regulation of tatiopterin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900979 activation of tatiopterin metabolism|up-regulation of tatiopterin metabolic process|positive regulation of tatiopterin metabolism|up regulation of tatiopterin metabolism|upregulation of tatiopterin metabolic process|upregulation of tatiopterin metabolism|up regulation of tatiopterin metabolic process|activation of tatiopterin metabolic process|up-regulation of tatiopterin metabolism Any process that activates or increases the frequency, rate or extent of tatiopterin metabolic process. GO:1900976 positive regulation of tatiopterin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900976 upregulation of tatiopterin formation|positive regulation of tatiopterin biosynthesis|up regulation of tatiopterin anabolism|positive regulation of tatiopterin anabolism|up regulation of tatiopterin biosynthesis|up regulation of tatiopterin biosynthetic process|up regulation of tatiopterin synthesis|positive regulation of tatiopterin synthesis|activation of tatiopterin anabolism|up regulation of tatiopterin formation|positive regulation of tatiopterin formation|activation of tatiopterin synthesis|upregulation of tatiopterin biosynthetic process|upregulation of tatiopterin biosynthesis|up-regulation of tatiopterin anabolism|activation of tatiopterin formation|up-regulation of tatiopterin synthesis|up-regulation of tatiopterin formation|up-regulation of tatiopterin biosynthetic process|up-regulation of tatiopterin biosynthesis|activation of tatiopterin biosynthetic process|upregulation of tatiopterin anabolism|upregulation of tatiopterin synthesis|activation of tatiopterin biosynthesis Any process that activates or increases the frequency, rate or extent of tatiopterin biosynthetic process. CHEBI:21037 aldohexose phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21037 GO:1900975 negative regulation of tatiopterin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900975 negative regulation of tatiopterin biosynthesis|down-regulation of tatiopterin biosynthetic process|down-regulation of tatiopterin biosynthesis|down regulation of tatiopterin synthesis|downregulation of tatiopterin anabolism|down regulation of tatiopterin formation|downregulation of tatiopterin synthesis|downregulation of tatiopterin formation|downregulation of tatiopterin biosynthesis|downregulation of tatiopterin biosynthetic process|down-regulation of tatiopterin anabolism|negative regulation of tatiopterin anabolism|down regulation of tatiopterin biosynthesis|down regulation of tatiopterin biosynthetic process|inhibition of tatiopterin biosynthetic process|down-regulation of tatiopterin synthesis|negative regulation of tatiopterin synthesis|down-regulation of tatiopterin formation|negative regulation of tatiopterin formation|inhibition of tatiopterin biosynthesis|inhibition of tatiopterin anabolism|inhibition of tatiopterin synthesis|down regulation of tatiopterin anabolism|inhibition of tatiopterin formation Any process that stops, prevents or reduces the frequency, rate or extent of tatiopterin biosynthetic process. GO:1900978 negative regulation of tatiopterin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900978 down-regulation of tatiopterin metabolic process|down-regulation of tatiopterin metabolism|negative regulation of tatiopterin metabolism|inhibition of tatiopterin metabolic process|downregulation of tatiopterin metabolism|down regulation of tatiopterin metabolism|down regulation of tatiopterin metabolic process|downregulation of tatiopterin metabolic process|inhibition of tatiopterin metabolism Any process that stops, prevents or reduces the frequency, rate or extent of tatiopterin metabolic process. GO:1900977 regulation of tatiopterin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900977 regulation of tatiopterin metabolism Any process that modulates the frequency, rate or extent of tatiopterin metabolic process. GO:1900972 negative regulation of sarcinapterin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900972 inhibition of sarcinapterin biosynthesis|inhibition of sarcinapterin anabolism|inhibition of sarcinapterin synthesis|inhibition of sarcinapterin formation|down regulation of sarcinapterin anabolism|down-regulation of sarcinapterin biosynthetic process|down-regulation of sarcinapterin biosynthesis|negative regulation of sarcinapterin biosynthesis|downregulation of sarcinapterin anabolism|down regulation of sarcinapterin synthesis|down regulation of sarcinapterin formation|downregulation of sarcinapterin synthesis|downregulation of sarcinapterin formation|downregulation of sarcinapterin biosynthesis|downregulation of sarcinapterin biosynthetic process|negative regulation of sarcinapterin anabolism|down-regulation of sarcinapterin anabolism|down regulation of sarcinapterin biosynthesis|down regulation of sarcinapterin biosynthetic process|negative regulation of sarcinapterin synthesis|down-regulation of sarcinapterin synthesis|inhibition of sarcinapterin biosynthetic process|negative regulation of sarcinapterin formation|down-regulation of sarcinapterin formation Any process that stops, prevents or reduces the frequency, rate or extent of sarcinapterin biosynthetic process. GO:1900971 regulation of sarcinapterin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900971 regulation of sarcinapterin anabolism|regulation of sarcinapterin synthesis|regulation of sarcinapterin formation|regulation of sarcinapterin biosynthesis Any process that modulates the frequency, rate or extent of sarcinapterin biosynthetic process. GO:1900974 regulation of tatiopterin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900974 regulation of tatiopterin synthesis|regulation of tatiopterin formation|regulation of tatiopterin biosynthesis|regulation of tatiopterin anabolism Any process that modulates the frequency, rate or extent of tatiopterin biosynthetic process. GO:1900973 positive regulation of sarcinapterin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900973 up-regulation of sarcinapterin anabolism|activation of sarcinapterin formation|up-regulation of sarcinapterin synthesis|up-regulation of sarcinapterin formation|activation of sarcinapterin biosynthetic process|up-regulation of sarcinapterin biosynthetic process|up-regulation of sarcinapterin biosynthesis|upregulation of sarcinapterin anabolism|upregulation of sarcinapterin synthesis|activation of sarcinapterin biosynthesis|upregulation of sarcinapterin formation|up regulation of sarcinapterin anabolism|positive regulation of sarcinapterin biosynthesis|up regulation of sarcinapterin biosynthesis|positive regulation of sarcinapterin anabolism|up regulation of sarcinapterin biosynthetic process|up regulation of sarcinapterin synthesis|positive regulation of sarcinapterin synthesis|up regulation of sarcinapterin formation|activation of sarcinapterin anabolism|positive regulation of sarcinapterin formation|activation of sarcinapterin synthesis|upregulation of sarcinapterin biosynthesis|upregulation of sarcinapterin biosynthetic process Any process that activates or increases the frequency, rate or extent of sarcinapterin biosynthetic process. GO:1900970 positive regulation of sarcinapterin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900970 upregulation of sarcinapterin metabolism|up regulation of sarcinapterin metabolic process|activation of sarcinapterin metabolic process|up-regulation of sarcinapterin metabolism|activation of sarcinapterin metabolism|up-regulation of sarcinapterin metabolic process|positive regulation of sarcinapterin metabolism|up regulation of sarcinapterin metabolism|upregulation of sarcinapterin metabolic process Any process that activates or increases the frequency, rate or extent of sarcinapterin metabolic process. GO:0022819 potassium ion uniporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022819 Catalysis of the active transport of a potassium ion across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged. CHEBI:35674 antihypertensive agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35674 CHEBI:35673 abietane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35673 GO:0022818 sodium ion uniporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022818 Catalysis of the active transport of a sodium ion across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged. CHEBI:59640 N-acetylglucosamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59640 CHEBI:35676 benzazepine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35676 GO:0071869 response to catecholamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071869 response to catecholamine stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution. GO:0071868 cellular response to monoamine stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071868 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan. GO:0071867 response to monoamine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071867 response to monoamine stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan. CHEBI:35679 antilipemic drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35679 GO:0071866 negative regulation of apoptotic process in bone marrow cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071866 negative regulation of bone marrow cell programmed cell death by apoptosis|negative regulation of apoptosis in bone marrow|negative regulation of bone marrow cell apoptosis|negative regulation of apoptotic process in bone marrow|down-regulation of apoptosis in bone marrow|negative regulation of programmed cell death, bone marrow cells|downregulation of apoptosis in bone marrow|down regulation of apoptosis in bone marrow|negative regulation of killing of bone marrow cells|inhibition of apoptosis in bone marrow|negative regulation of programmed cell death of bone marrow cells by apoptosis Any process that stops, prevents, or reduces the frequency, rate or extent of the occurrence or rate of cell death by apoptotic process in the bone marrow. GO:0071865 regulation of apoptotic process in bone marrow cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071865 regulation of apoptosis in bone marrow|regulation of apoptotic process in bone marrow Any process that modulates the occurrence or rate of cell death by apoptotic process in the bone marrow. GO:0022810 membrane potential driven uniporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022810 porter Enables the active transport of a solute across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged. CHEBI:59648 precursor Z(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59648 GO:0071864 positive regulation of cell proliferation in bone marrow biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071864 stimulation of cell proliferation in bone marrow|up-regulation of cell proliferation in bone marrow|positive regulation of bone marrow cell proliferation|upregulation of cell proliferation in bone marrow|up regulation of cell proliferation in bone marrow|activation of cell proliferation in bone marrow A process that activates or increases the frequency, rate or extent of cell proliferation in the bone marrow. CHEBI:59647 EC 2.3.1.50 (serine C-palmitoyltransferase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59647 GO:0071863 regulation of cell proliferation in bone marrow biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071863 regulation of bone marrow cell proliferation A process that modulates the frequency, rate or extent of cell proliferation in the bone marrow. GO:0022815 obsolete large uncharged polar molecule transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022815 large uncharged polar molecule transmembrane transporter activity OBSOLETE. Catalysis of the transfer of a large uncharged polar molecule from one side of a membrane to the other. GO:0071862 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0071862 GO:0022814 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0022814 GO:0071861 tachykinin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071861 Interacting selectively and non-covalently with a tachykinin receptor. CHEBI:59644 oxo fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59644 GO:0022817 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0022817 GO:0071860 proctolin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071860 Interacting selectively and non-covalently with a proctolin receptor. CHEBI:59643 thia fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59643 GO:0022816 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0022816 GO:1900987 ajmaline catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900987 ajmaline breakdown|ajmaline catabolism|ajmaline degradation The chemical reactions and pathways resulting in the breakdown of ajmaline. GO:1900986 ajmaline metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900986 ajmaline metabolism The chemical reactions and pathways involving ajmaline. GO:1900989 scopolamine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900989 scopolamine metabolism The chemical reactions and pathways involving scopolamine. GO:1900988 ajmaline biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900988 ajmaline anabolism|ajmaline synthesis|ajmaline formation|ajmaline biosynthesis The chemical reactions and pathways resulting in the formation of ajmaline. GO:1900983 vindoline metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900983 vindoline metabolism The chemical reactions and pathways involving vindoline. GO:1900982 positive regulation of phenazine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900982 activation of dibenzo-p-diazine biosynthesis|up-regulation of dibenzopyrazine biosynthetic process|up-regulation of dibenzopyrazine biosynthesis|activation of dibenzo-p-diazine biosynthetic process|up-regulation of azophenylene biosynthesis|up-regulation of azophenylene biosynthetic process|positive regulation of dibenzo-p-diazine biosynthetic process|positive regulation of dibenzo-p-diazine biosynthesis|activation of dibenzopyrazine biosynthetic process|activation of dibenzopyrazine biosynthesis|up regulation of dibenzo-p-diazine biosynthesis|up regulation of dibenzo-p-diazine biosynthetic process|up regulation of acridizine biosynthesis|up-regulation of phenazine biosynthetic process|up regulation of acridizine biosynthetic process|activation of phenazine biosynthetic process|positive regulation of acridizine biosynthetic process|positive regulation of acridizine biosynthesis|positive regulation of dibenzopyrazine biosynthesis|positive regulation of dibenzopyrazine biosynthetic process|upregulation of azophenylene biosynthesis|upregulation of azophenylene biosynthetic process|up regulation of dibenzopyrazine biosynthetic process|up regulation of dibenzopyrazine biosynthesis|activation of acridizine biosynthesis|activation of acridizine biosynthetic process|upregulation of dibenzo-p-diazine biosynthesis|upregulation of dibenzo-p-diazine biosynthetic process|up-regulation of acridizine biosynthesis|up-regulation of acridizine biosynthetic process|up regulation of phenazine biosynthetic process|up regulation of azophenylene biosynthesis|up regulation of azophenylene biosynthetic process|upregulation of dibenzopyrazine biosynthetic process|upregulation of dibenzopyrazine biosynthesis|positive regulation of azophenylene biosynthetic process|positive regulation of azophenylene biosynthesis|up-regulation of dibenzo-p-diazine biosynthetic process|up-regulation of dibenzo-p-diazine biosynthesis|activation of azophenylene biosynthesis|activation of azophenylene biosynthetic process|upregulation of acridizine biosynthetic process|upregulation of acridizine biosynthesis|upregulation of phenazine biosynthetic process Any process that activates or increases the frequency, rate or extent of phenazine biosynthetic process. GO:1900985 vindoline biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900985 vindoline anabolism|vindoline biosynthesis|vindoline synthesis|vindoline formation The chemical reactions and pathways resulting in the formation of vindoline. GO:1900984 vindoline catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900984 vindoline degradation|vindoline breakdown|vindoline catabolism The chemical reactions and pathways resulting in the breakdown of vindoline. CHEBI:21040 D-idarate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_21040 GO:1900981 negative regulation of phenazine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900981 negative regulation of dibenzo-p-diazine biosynthesis|down regulation of acridizine biosynthetic process|negative regulation of dibenzo-p-diazine biosynthetic process|down-regulation of dibenzo-p-diazine biosynthetic process|down-regulation of dibenzo-p-diazine biosynthesis|down regulation of acridizine biosynthesis|downregulation of acridizine biosynthesis|downregulation of acridizine biosynthetic process|down-regulation of dibenzopyrazine biosynthetic process|down-regulation of dibenzopyrazine biosynthesis|negative regulation of dibenzopyrazine biosynthetic process|negative regulation of dibenzopyrazine biosynthesis|inhibition of azophenylene biosynthetic process|inhibition of azophenylene biosynthesis|downregulation of dibenzo-p-diazine biosynthesis|downregulation of dibenzo-p-diazine biosynthetic process|negative regulation of acridizine biosynthesis|down-regulation of acridizine biosynthesis|down regulation of dibenzo-p-diazine biosynthetic process|negative regulation of acridizine biosynthetic process|down-regulation of acridizine biosynthetic process|down regulation of dibenzo-p-diazine biosynthesis|down-regulation of phenazine biosynthetic process|down regulation of azophenylene biosynthesis|down regulation of azophenylene biosynthetic process|downregulation of dibenzopyrazine biosynthesis|downregulation of dibenzopyrazine biosynthetic process|downregulation of azophenylene biosynthesis|downregulation of azophenylene biosynthetic process|down regulation of dibenzopyrazine biosynthetic process|down regulation of dibenzopyrazine biosynthesis|inhibition of dibenzo-p-diazine biosynthesis|inhibition of dibenzo-p-diazine biosynthetic process|downregulation of phenazine biosynthetic process|inhibition of acridizine biosynthesis|inhibition of acridizine biosynthetic process|inhibition of dibenzopyrazine biosynthesis|inhibition of dibenzopyrazine biosynthetic process|down-regulation of azophenylene biosynthetic process|negative regulation of azophenylene biosynthesis|down regulation of phenazine biosynthetic process|negative regulation of azophenylene biosynthetic process|down-regulation of azophenylene biosynthesis|inhibition of phenazine biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of phenazine biosynthetic process. GO:1900980 regulation of phenazine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900980 regulation of acridizine biosynthetic process|regulation of acridizine biosynthesis|regulation of dibenzo-p-diazine biosynthesis|regulation of dibenzo-p-diazine biosynthetic process|regulation of azophenylene biosynthetic process|regulation of azophenylene biosynthesis|regulation of dibenzopyrazine biosynthetic process|regulation of dibenzopyrazine biosynthesis Any process that modulates the frequency, rate or extent of phenazine biosynthetic process. CHEBI:21041 D-idaric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21041 CHEBI:35684 antiplatyhelmintic drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35684 GO:0022809 mobile ion carrier activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022809 ionophore Small molecule produced by bacteria that carries an ion across the membrane by enclosing the ion and travelling with the ion across the membrane. It does not form a fully open pore across the membrane. GO:0071859 neuropeptide F receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071859 Interacting selectively and non-covalently with a neuropeptide F receptor. CHEBI:35689 tetrazoles biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35689 GO:0071858 corazonin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071858 Interacting selectively and non-covalently with a corazonin receptor. CHEBI:35688 benzimidazolecarboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35688 GO:0071857 beta-endorphin receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071857 Interacting selectively and non-covalently with a beta-endorphin receptor. GO:0071856 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0071856 GO:0071855 neuropeptide receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071855 Interacting selectively and non-covalently with a neuropeptide receptor. GO:0071854 cell wall macromolecule catabolic process involved in fungal-type cell wall disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071854 The chemical reactions and pathways that result in the breakdown of macromolecules that form part of a cell wall, and contributes to the breakdown of the fungal-type cell wall. GO:0071853 fungal-type cell wall disassembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071853 A cellular process that results in the breakdown of a fungal-type cell wall. GO:0071852 fungal-type cell wall organization or biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071852 fungal-type cell wall organisation or biogenesis|fungal-type cell wall organization and biogenesis A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a fungal-type cell wall. CHEBI:59635 organophosphonate oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59635 GO:0022804 active transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022804 carrier activity|active carrier activity|permease activity|pump activity Enables the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction. CHEBI:35681 secondary alcohol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35681 GO:0071851 mitotic G1 cell cycle arrest in response to nitrogen starvation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071851 G1 mitotic cell cycle arrest in response to nitrogen starvation The process in which the mitotic cell cycle is halted during G1 phase, as a result of deprivation of nitrogen. GO:0022803 passive transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022803 Reactome:R-HSA-429767|Wikipedia:Facilitated_diffusion porters|uniporter activity z|facilitated diffusion Enables the transfer of a single solute from one side of a membrane to the other by a mechanism involving conformational change, either by facilitated diffusion or in a membrane potential dependent process if the solute is charged. GO:0071850 mitotic cell cycle arrest biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071850 termination of mitotic cell cycle|arrest of mitotic cell cycle progression|cessation of mitotic cell cycle The process in which the mitotic cell cycle is halted during one of the normal phases (G1, S, G2, M). CHEBI:59633 mycothiol S-conjugate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59633 CHEBI:35680 abietate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35680 CHEBI:35683 aryl sulfide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35683 GO:0032272 negative regulation of protein polymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032272 inhibition of protein polymerization|down-regulation of protein polymerization|downregulation of protein polymerization|down regulation of protein polymerization Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers. GO:0032271 regulation of protein polymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032271 regulation of protein polymerisation Any process that modulates the frequency, rate or extent of the process of creating protein polymers. GO:0032270 positive regulation of cellular protein metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032270 positive regulation of cellular protein metabolism|upregulation of cellular protein metabolic process|stimulation of cellular protein metabolic process|up-regulation of cellular protein metabolic process|activation of cellular protein metabolic process|up regulation of cellular protein metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell. CHEBI:60625 N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-Asn residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60625 CHEBI:60627 N(4)-{alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-Asn residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60627 GO:0032279 asymmetric synapse biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032279 Gray's type I synapse A type of synapse occurring between an axon and a dendritic spine or dendritic shaft. Asymmetric synapses, the most abundant synapse type in the central nervous system, involve axons that contain predominantly spherical vesicles and contain a thickened postsynaptic density. Most or all synapses of this type are excitatory. GO:0032278 positive regulation of gonadotropin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032278 positive regulation of gonadotrophin secretion|up regulation of gonadotropin secretion|upregulation of gonadotropin secretion|stimulation of gonadotropin secretion|activation of gonadotropin secretion|up-regulation of gonadotropin secretion Any process that activates or increases the frequency, rate or extent of the regulated release of a gonadotropin. CHEBI:60628 N(4)-{alpha-D-Manp-(1->2)-alpha-D-Manp-(1->2)-alpha-D-Manp-(1->3)-[alpha-D-Manp-(1->3)-[alpha-D-Manp-(1->2)-alpha-D-Manp-(1->6)]-alpha-D-Manp-(1->6)]-beta-D-Manp-(1->4)-beta-D-GlcpNAc-(1->4)-beta-D-GlcpNAc}-Asn residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60628 GO:0032277 negative regulation of gonadotropin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032277 down-regulation of gonadotropin secretion|negative regulation of gonadotrophin secretion|downregulation of gonadotropin secretion|down regulation of gonadotropin secretion|inhibition of gonadotropin secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a gonadotropin. GO:0032276 regulation of gonadotropin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032276 regulation of gonadotrophin secretion Any process that modulates the frequency, rate or extent of the regulated release of a gonadotropin. GO:0032275 luteinizing hormone secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032275 The regulated release of luteinizing hormone, a gonadotropic glycoprotein hormone secreted by the anterior pituitary. GO:0032274 gonadotropin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032274 gonadotrophin secretion The regulated release of a gonadotropin, any hormone that stimulates the gonads, especially follicle-stimulating hormone and luteinizing hormone. GO:0032273 positive regulation of protein polymerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032273 upregulation of protein polymerization|stimulation of protein polymerization|up-regulation of protein polymerization|activation of protein polymerization|up regulation of protein polymerization Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers. GO:0032261 purine nucleotide salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032261 Any process which produces a purine nucleotide from derivatives of it, without de novo synthesis. GO:0032260 response to jasmonic acid stimulus involved in jasmonic acid and ethylene-dependent systemic resistance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032260 response to jasmonic acid stimulus during jasmonic acid and ethylene-dependent systemic resistance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus received in the context of the jasmonic acid- and ethylene (ethene)-dependent process that confers broad spectrum systemic resistance to disease in response to wounding or a pathogen. GO:0032269 negative regulation of cellular protein metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032269 down-regulation of cellular protein metabolic process|downregulation of cellular protein metabolic process|down regulation of cellular protein metabolic process|inhibition of cellular protein metabolic process|negative regulation of cellular protein metabolism Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell. CHEBI:60637 N(4)-{alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-Asn residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60637 GO:0032268 regulation of cellular protein metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032268 regulation of cellular protein metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell. GO:0032267 tRNA(Ile)-lysidine synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032267 EC:6.3.4.- tRNA(Ile)-lysidine synthetase activity|tRNA(Ile)-2-lysyl-cytidine synthase activity Catalysis of the ligation of lysine onto the cytidine residue present at the wobble position (usually position 34) of an AUA-specific isoleucine tRNA, to form the derivative lysidine. This modification converts both the codon specificity of tRNA(Ile) from AUG to AUA and its amino acid specificity from methionine to isoleucine. GO:0032266 phosphatidylinositol-3-phosphate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032266 phosphatidylinositol 3-phosphate binding|PtdIns-3-P binding Interacting selectively and non-covalently with phosphatidylinositol-3-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' position. GO:0032265 XMP salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032265 Any process which produces xanthosine monophosphate from derivatives of it, without de novo synthesis. GO:0032264 IMP salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032264 Any process which produces inosine monophosphate from derivatives of it, without de novo synthesis. GO:0032263 GMP salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032263 Any process which produces guanosine monophosphate from derivatives of it, without de novo synthesis. GO:0032262 pyrimidine nucleotide salvage biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032262 Any process which produces a pyrimidine nucleotide from derivatives of it, without de novo synthesis. GO:0032259 methylation biolink:BiologicalProcess go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0032259 Wikipedia:Methylation The process in which a methyl group is covalently attached to a molecule. CHEBI:142797 TMP(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142797 CHEBI:84603 all-trans-tridecaprenyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84603 CHEBI:142796 5-methyl-CMP(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142796 CHEBI:84602 all-trans-dodecaprenyl diphosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84602 GO:0007299 ovarian follicle cell-cell adhesion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007299 ovarian follicle cell adhesion|follicle cell adhesion The attachment of a somatic follicle cell to another somatic follicle cell or to its substratum, the germline cells. An example of this is found in Drosophila melanogaster. GO:0007298 border follicle cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007298 border cell migration The directed movement of a border cell through the nurse cells to reach the oocyte. An example of this is found in Drosophila melanogaster. CHEBI:84601 3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1,5-dioxo-octahydroinden-4-yl]propanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84601 GO:0007297 ovarian follicle cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007297 follicle cell migration The directed movement of an ovarian follicle cell that takes place during oogenesis. During egg chamber formation, follicle cells migrate to envelop the germ-line cysts and move in between cysts. At stage 10B, follicle cells migrate centripetally between the nurse cells and the oocyte, enclosing the anterior of the egg. An example of this is found in Drosophila melanogaster. CHEBI:84600 all-trans-tridecaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84600 GO:0007296 vitellogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007296 Wikipedia:Vitellogenesis yolk production|yolk formation The production of yolk. Yolk is a mixture of materials used for embryonic nutrition. GO:0007295 growth of a germarium-derived egg chamber biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007295 egg chamber growth Growth of the egg chamber between the time it leaves the germarium and the onset of vitellogenesis. During this time both nurse cells and the oocyte undergo developmental changes including nuclear organization and cytoplasmic growth. An example of this is found in Drosophila melanogaster. GO:0032250 negative regulation of adenosine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032250 downregulation of adenosine transport|down-regulation of adenosine transport|inhibition of adenosine transport|down regulation of adenosine transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:60643 NMDA receptor antagonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60643 CHEBI:60645 2-hydroxy-3-methylbutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60645 GO:0032258 cytoplasm to vacuole transport by the Cvt pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032258 cytoplasm-to-vacuole targeting|cytoplasm to vacuole targeting|protein localization by the Cvt pathway A cytoplasm to vacuole targeting pathway that uses machinery common with autophagy. The Cvt vesicle is formed when the receptor protein, Atg19, binds to the complexes of the target protein (aminopeptidase or alpha-mannosidase homododecamers), forming the Cvt complex. Atg11 binds to Atg9 and transports the Cvt complex to the pre-autophagosome (PAS). The phagophore membrane expands around the Cvt complex (excluding bulk cytoplasm) forming the Cvt vesicle. This pathway is mostly observed in yeast. GO:0032257 maintenance of dense core granule location biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032257 maintenance of dense core vesicle location|maintenance of dense core granule localization Any process in which a dense core granule is maintained in a specific location within a cell and prevented from moving elsewhere. GO:0032256 establishment of dense core granule localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032256 establishment of dense core granule localisation|establishment of dense core vesicle localization The directed movement of a dense core granule to a specific location. GO:0032255 maintenance of secretory granule location biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032255 maintenance of secretory granule localization Any process in which a secretory granule is maintained in a specific location within a cell and prevented from moving elsewhere. GO:0032254 establishment of secretory granule localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032254 establishment of secretory granule localisation The directed movement of a secretory granule to a specific location. GO:0032253 dense core granule localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032253 dense core granule localisation|dense core vesicle localization|dense core granule clustering Any process in which a dense core granule is transported to, and/or maintained in, a specific location within the cell. GO:0032252 secretory granule localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032252 secretory granule clustering|secretory granule localisation Any process in which a secretory granule is transported to, and/or maintained in, a specific location within the cell. GO:0032251 positive regulation of adenosine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032251 up regulation of adenosine transport|activation of adenosine transport|stimulation of adenosine transport|up-regulation of adenosine transport|upregulation of adenosine transport Any process that activates or increases the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0032249 regulation of adenosine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032249 Any process that modulates the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:84618 3-hydroxy-9-oxo-9,10-seco-23,24-bisnorchola-1,3,5(10)-trien-22-oyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84618 GO:0032248 positive regulation of purine nucleoside transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032248 upregulation of purine nucleoside transport|up regulation of purine nucleoside transport|activation of purine nucleoside transport|stimulation of purine nucleoside transport|up-regulation of purine nucleoside transport Any process that activates or increases the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:84617 3-oxo-23,24-bisnorchola-1,4-dien-22-oyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84617 CHEBI:84616 3-oxo-23,24-bisnorchol-4-en-22-oyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84616 CHEBI:60651 N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAcl-(1->4)-beta-D-GlcNAc}-Asn residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60651 CHEBI:60653 1-stearoyl-2-oleoyl-sn-glycero-3-phosphocholine(1+) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60653 CHEBI:60656 5-methoxy-2-methyl-3-octaprenylhydroquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60656 CHEBI:60655 6-methoxy-2-octaprenylhydroquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60655 CHEBI:60657 1,2-di-O-arachidonoyl-sn-glycero-3-phosphocholine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60657 GO:0032247 negative regulation of purine nucleoside transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032247 down regulation of purine nucleoside transport|downregulation of purine nucleoside transport|down-regulation of purine nucleoside transport|inhibition of purine nucleoside transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0032246 regulation of pyrimidine nucleoside transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032246 Any process that modulates the frequency, rate or extent of the directed movement of a pyrimidine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0032245 regulation of purine nucleoside transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032245 Any process that modulates the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0032244 positive regulation of nucleoside transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032244 up regulation of nucleoside transport|upregulation of nucleoside transport|stimulation of nucleoside transport|up-regulation of nucleoside transport|activation of nucleoside transport Any process that activates or increases the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0032243 negative regulation of nucleoside transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032243 down-regulation of nucleoside transport|downregulation of nucleoside transport|down regulation of nucleoside transport|inhibition of nucleoside transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0032242 regulation of nucleoside transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032242 Any process that modulates the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0032241 positive regulation of nucleobase-containing compound transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032241 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport|up regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport|activation of nucleobase, nucleoside, nucleotide and nucleic acid transport|stimulation of nucleobase, nucleoside, nucleotide and nucleic acid transport|up-regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport|upregulation of nucleobase, nucleoside, nucleotide and nucleic acid transport Any process that activates or increases the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0032240 negative regulation of nucleobase-containing compound transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032240 downregulation of nucleobase, nucleoside, nucleotide and nucleic acid transport|negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport|down-regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport|inhibition of nucleobase, nucleoside, nucleotide and nucleic acid transport|down regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0032239 regulation of nucleobase-containing compound transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032239 regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport Any process that modulates the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0032238 adenosine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032238 The directed movement of adenosine, adenine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0032237 activation of store-operated calcium channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032237 A process that initiates the activity of an inactive store-operated calcium channel. GO:0046800 obsolete enhancement of virulence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046800 enhancement of virulence OBSOLETE. Any process that activates or increases the severity of viral infection and subsequent disease. GO:0007279 pole cell formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007279 Formation of a small group of cells (pole cells) at the posterior pole of the insect blastula. They are the first cells to cellularize after the arrival of nuclei at the end of the syncytial blastula stage and are the precursors to the insect germ cells. GO:0007278 pole cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007278 The cell fate determination process in which a cell becomes capable of differentiating autonomously into a pole cell regardless of its environment; upon determination, the cell fate cannot be reversed. GO:0007277 pole cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007277 The process whose specific outcome is the progression of the pole cell over time, from its formation to the mature structure. GO:0007276 gamete generation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007276 gametogenesis The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell. GO:0007275 multicellular organism development biolink:BiologicalProcess go-plus goslim_chembl|goslim_plant http://purl.obolibrary.org/obo/GO_0007275 The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). GO:0007274 neuromuscular synaptic transmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007274 The process of synaptic transmission from a neuron to a muscle, across a synapse. GO:0007273 obsolete regulation of synapse biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007273 regulation of synapse OBSOLETE. (Was not defined before being made obsolete). GO:0007283 spermatogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007283 Wikipedia:Spermatogenesis generation of spermatozoa The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa. GO:0046808 obsolete assemblon biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0046808 OBSOLETE. Antigenically dense structures located at the periphery of nuclei, close to but not abutting nuclear membranes. Assemblons contain the proteins for immature-capsid assembly; they are located at the periphery of a diffuse structure composed of proteins involved in DNA synthesis, which overlaps only minimally with the assemblons. More than one site can be present simultaneously. GO:0007282 cystoblast division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007282 cystoblast cell division Any of the rounds of incomplete mitosis undergone by a cystoblast to form a cyst of interconnected cells. GO:0046807 viral scaffold assembly and maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046807 The assembly and maintenance of the viral scaffold around which the viral capsid is constructed. GO:0007281 germ cell development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007281 primordial germ cell development|germ-cell development The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism. GO:0046806 viral scaffold biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0046806 A complex of proteins that form a scaffold around which the viral capsid is constructed. GO:0007280 pole cell migration biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007280 The directed movement of a pole cell (germline progenitors in insects) from its site of production at the posterior pole of the embryo through to the site where the gonads will form. GO:0046805 protein-heme linkage via 1'-L-histidine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046805 RESID:AA0329 protein-haem linkage via 1'-L-histidine The covalent linkage of heme and a protein via 1'-L-histidine (otherwise known as tau-heme-histidine, tele-heme-histidine). GO:0046804 peptide cross-linking via (2S,3S,4Xi,6R)-3-methyl-lanthionine sulfoxide biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046804 RESID:AA0330 peptide cross-linking via (2S,3S,4Xi,6R)-3-methyl-lanthionine sulphoxide The formation of a protein-protein cross-link between peptidyl-threonine and peptidyl-cysteine by the synthesis of (2S,3S,4Xi,6R)-3-methyl-lanthionine sulfoxide (3-methyl-L-lanthionine sulfoxide), as found in the antibiotic actagardine. GO:0046803 obsolete reduction of virulence biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046803 reduction of virulence OBSOLETE. Any process that stops, prevents or reduces the severity of viral infection and subsequent disease. GO:0046802 exit of virus from host cell nucleus by nuclear egress biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046802 VZ:1952 capsid egress|nuclear egress|egress of viral procapsid from host cell nucleus|nuclear egress of viral procapsid The directed movement of an assembled viral particle out of the host cell nucleus by budding and fusion through the nuclear membranes. In this process, enveloped viral particles are formed by budding through the inner nuclear membrane. These perinuclear enveloped particles then fuse with the outer nuclear membrane to deliver a naked capsid into the host cytoplasm. GO:0046801 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046801 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032236 up regulation of calcium ion transport via store-operated calcium channel|positive regulation of calcium ion transport via store-operated calcium channel activity|upregulation of calcium ion transport via store-operated calcium channel|positive regulation of store-operated calcium channel activity|stimulation of calcium ion transport via store-operated calcium channel|up-regulation of calcium ion transport via store-operated calcium channel|activation of calcium ion transport via store-operated calcium channel|positive regulation of calcium transport via store-operated calcium channel OBSOLETE. Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions via a store-operated calcium channel. GO:0032235 obsolete negative regulation of calcium ion transport via store-operated calcium channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032235 downregulation of calcium ion transport via store-operated calcium channel|negative regulation of calcium ion transport via store-operated calcium channel activity|down regulation of calcium ion transport via store-operated calcium channel|inhibition of calcium ion transport via store-operated calcium channel|negative regulation of calcium transport via store-operated calcium channel|negative regulation of store-operated calcium channel activity|down-regulation of calcium ion transport via store-operated calcium channel OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions via a store-operated calcium channel. GO:0032234 obsolete regulation of calcium ion transport via store-operated calcium channel activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032234 regulation of calcium transport via store-operated calcium channel|regulation of store-operated calcium channel activity|regulation of calcium ion transport via store-operated calcium channel activity OBSOLETE. Any process that modulates the frequency, rate or extent of the directed movement of calcium ions via a store-operated calcium channel. GO:0032233 positive regulation of actin filament bundle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032233 upregulation of actin filament bundle formation|up regulation of actin filament bundle formation|activation of actin filament bundle formation|stimulation of actin filament bundle formation|up-regulation of actin filament bundle formation Any process that activates or increases the frequency, rate or extent of the assembly of actin filament bundles. GO:0032232 negative regulation of actin filament bundle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032232 down regulation of actin filament bundle formation|downregulation of actin filament bundle formation|down-regulation of actin filament bundle formation|inhibition of actin filament bundle formation Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin filament bundles. GO:0032231 regulation of actin filament bundle assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032231 regulation of actin filament bundle formation|regulation of actin cable assembly Any process that modulates the frequency, rate or extent of the assembly of actin filament bundles. GO:0032230 positive regulation of synaptic transmission, GABAergic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032230 upregulation of synaptic transmission, GABAergic|stimulation of synaptic transmission, GABAergic|up-regulation of synaptic transmission, GABAergic|activation of synaptic transmission, GABAergic|up regulation of synaptic transmission, GABAergic Any process that activates, maintains or increases the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA). GO:0046809 replication compartment biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0046809 RC Globular nuclear domains where the transcription and replication of the viral genome occurs. More than one site can be present simultaneously. GO:0032229 negative regulation of synaptic transmission, GABAergic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032229 down-regulation of synaptic transmission, GABAergic|downregulation of synaptic transmission, GABAergic|down regulation of synaptic transmission, GABAergic|inhibition of synaptic transmission, GABAergic Any process that stops, prevents, or reduces the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA). GO:0032228 regulation of synaptic transmission, GABAergic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032228 Any process that modulates the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA). GO:0032227 negative regulation of synaptic transmission, dopaminergic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032227 inhibition of synaptic transmission, dopaminergic|down regulation of synaptic transmission, dopaminergic|downregulation of synaptic transmission, dopaminergic|down-regulation of synaptic transmission, dopaminergic Any process that stops, prevents, or reduces the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine. GO:0032226 positive regulation of synaptic transmission, dopaminergic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032226 up-regulation of synaptic transmission, dopaminergic|upregulation of synaptic transmission, dopaminergic|up regulation of synaptic transmission, dopaminergic|activation of synaptic transmission, dopaminergic|stimulation of synaptic transmission, dopaminergic Any process that activates, maintains or increases the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine. GO:0046811 histone deacetylase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046811 Stops, prevents or reduces the activity of histone deacetylase, which catalyzes of the removal of acetyl groups from histones, proteins complexed to DNA in chromatin and chromosomes. GO:0046810 host cell extracellular matrix binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046810 Interacting selectively and non-covalently with the extracellular matrix of a host cell. GO:0007289 spermatid nucleus differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007289 spermatid nuclear differentiation The specialization of the spermatid nucleus during the development of a spermatid into a mature male gamete competent for fertilization. GO:0007288 sperm axoneme assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007288 The assembly and organization of the sperm flagellar axoneme, the bundle of microtubules and associated proteins that forms the core of the eukaryotic sperm flagellum, and is responsible for movement. GO:0007287 Nebenkern assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007287 Nebenkern assembly|Nebenkern formation Fusion of mitochondria during insect spermatid differentiation to form two masses, which wrap around each other to form a densely packed sphere called the Nebenkern. CHEBI:84634 O-tetradecanoyl-L-carnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84634 GO:0007286 spermatid development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007286 Wikipedia:Spermiogenesis spermatid cell development|spermiogenesis The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure. GO:0007285 primary spermatocyte growth biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007285 The phase of growth and gene expression that male germ cells undergo as they enter the spermatocyte stage. The cells grow in volume and transcribe most of the gene products needed for the morphological events that follow meiosis. GO:0007284 spermatogonial cell division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007284 spermatogonium division The mitotic divisions of the primary spermatogonial cell (a primordial male germ cell) to form secondary spermatogonia (primary spermatocytes). GO:0046819 protein secretion by the type V secretion system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046819 autotransporter system|type V protein secretion system|protein secretion by the autotransporter system|protein secretion by the type V protein secretion system The process in which proteins mediate their own secretion across the outer membrane through a beta-barrel pore structure formed by the C-terminal domain of the protein precursor. Following passage across the outer membrane, the mature protein is released from the pore by an autocatalytic activity. Proteins secreted by the Type V system are first translocated across the plasma membrane by the Sec pathway. GO:0007294 germarium-derived oocyte fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007294 maintenance of oocyte identity|oocyte cell fate determination The cell fate determination process in which a germarium-derived cell becomes capable of differentiating autonomously into an oocyte cell regardless of its environment; upon determination, the cell fate cannot be reversed. An example of this is found in Drosophila melanogaster. GO:0046818 dense nuclear body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0046818 A location in the host cell nucleus where viral proteins colocalize late in infection prior to the onset of viral DNA synthesis. More than one site can be present simultaneously. GO:0007293 germarium-derived egg chamber formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007293 Construction of a stage-1 egg chamber in the anterior part of the germarium, from the progeny of germ-line and somatic stem cells. An example of this is found in Drosophila melanogaster. GO:0046817 chemokine receptor antagonist activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046817 Interacts with chemokine receptors to reduce the action of a chemokine. GO:0007292 female gamete generation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007292 Generation of the female gamete; specialised haploid cells produced by meiosis and along with a male gamete takes part in sexual reproduction. GO:0046816 virion transport vesicle biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0046816 A vesicle used to transport the partial or complete virion between cellular compartments. GO:0007291 sperm individualization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007291 The resolution of the male germline syncytium or cyst into individual gametes by packaging each spermatid into its own plasma membrane. GO:0046815 genome retention in viral capsid biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046815 Any process in which the viral genome is retained within the capsid during genome cleavage and packaging. GO:0007290 spermatid nucleus elongation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007290 spermatid nuclear elongation The change in shape of the spermatid nucleus from a spherical structure to an elongated organelle, during the latter part of spermatid differentiation. GO:0046814 coreceptor-mediated virion attachment to host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046814 virion attachment, binding of host cell surface coreceptor The process by which a virion attaches to a host cell by binding to a co-receptor on the host cell surface. GO:0046813 receptor-mediated virion attachment to host cell biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046813 virion attachment, binding of host cell surface receptor The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface. CHEBI:142767 alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-Glc-yl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_142767 GO:0046812 host cell surface binding biolink:MolecularActivity go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0046812 Interacting selectively and non-covalently with the surface of a host cell. GO:0032225 regulation of synaptic transmission, dopaminergic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032225 Any process that modulates the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine. GO:0032224 positive regulation of synaptic transmission, cholinergic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032224 upregulation of synaptic transmission, cholinergic|stimulation of synaptic transmission, cholinergic|up-regulation of synaptic transmission, cholinergic|activation of synaptic transmission, cholinergic|up regulation of synaptic transmission, cholinergic Any process that activates, maintains or increases the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine. GO:0032223 negative regulation of synaptic transmission, cholinergic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032223 down regulation of synaptic transmission, cholinergic|inhibition of synaptic transmission, cholinergic|down-regulation of synaptic transmission, cholinergic|downregulation of synaptic transmission, cholinergic Any process that stops, prevents, or reduces the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine. GO:0032222 regulation of synaptic transmission, cholinergic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032222 Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine. GO:0032221 Rpd3S/Clr6-CII complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032221 Rpd3S complex|Clr6S complex|Clr6 histone deacetylase complex II|Rpd3C(S)|Clr6 histone deacetylase complex II'|Clr6-CII A eukaryotically conserved histone deacetylase complex which deacetylates histones across gene coding regions. Composed of a catalytic histone deacetylase subunit, a chromodomain protein, a SIN3 family co-repressor, and a WD repeat protein (Clr6p, Alp13p, Pst2p, and Prw1p respectively in Schizosaccharomyces; Rpd3p, Sin3p, Ume1p, Rco1p and Eaf3 in Saccharomyces; homologs thereof in other species). GO:0032220 plasma membrane fusion involved in cytogamy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032220 plasma membrane fusion during cytogamy|plasma membrane organization involved in conjugation with cellular fusion The joining of two or more lipid bilayer membranes that surround cells, that contributes to cytogamy. GO:0022891 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0022891 GO:0022890 inorganic cation transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022890 trivalent inorganic cation transmembrane transporter activity|divalent inorganic cation transmembrane transporter activity|monovalent inorganic cation transmembrane transporter activity|di-, tri-valent inorganic cation transmembrane transporter activity Enables the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage. GO:0022893 low-affinity tryptophan transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022893 low-affinity tryptophan permease activity Catalysis of the low-affinity transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations. GO:0032219 cell wall macromolecule catabolic process involved in cytogamy biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032219 cell wall macromolecule catabolic process during cytogamy The chemical reactions and pathways resulting in the breakdown of macromolecules forming part of a cell wall that contribute to cytogamy. GO:0022892 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0022892 GO:0032218 riboflavin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032218 The directed movement of riboflavin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Riboflavin (vitamin B2) is a water-soluble B-complex vitamin, converted in the cell to FMN and FAD, cofactors required for the function of flavoproteins. GO:0022895 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0022895 GO:0032217 riboflavin transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032217 RHEA:35015|Reactome:R-HSA-3165230 riboflavin transporter activity Enables the transfer of riboflavin from one side of a membrane to the other. Riboflavin (vitamin B2) is a water-soluble B-complex vitamin, converted in the cell to FMN and FAD, cofactors required for the function of flavoproteins. GO:0022894 Intermediate conductance calcium-activated potassium channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022894 intermdiate conductance KCa channels|IK KCa channels|IK calcium-activated potassium channel activity Enables the transmembrane transfer of potassium by a channel with a unit conductance of 20 to 85 picoSiemens that opens in response to stimulus by internal calcium ions. Intermediate conductance calcium-activated potassium channels are more sensitive to calcium than are large conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism. GO:0032216 glucosaminyl-phosphatidylinositol O-acyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032216 glucosaminyl-phosphotidylinositol O-acyltransferase activity|GPI-inositol acyltransferase Catalysis of the reaction: glucosaminyl-phosphatidylinositol + fatty acyl-CoA = glucosaminyl-acyl-phasphotidylinositol + CoA. GO:0022897 proton-dependent peptide secondary active transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022897 hydrogen/oligopeptide symporter Enables the transfer of a peptide from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by proton movement. GO:0032215 positive regulation of telomere maintenance via semi-conservative replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032215 up regulation of telomere maintenance via semi-conservative replication|upregulation of telomere maintenance via semi-conservative replication|stimulation of telomere maintenance via semi-conservative replication|activation of telomere maintenance via semi-conservative replication|up-regulation of telomere maintenance via semi-conservative replication Any process that activates or increases the frequency, rate or extent of the semi-conservative replication of telomeric DNA. GO:0007259 receptor signaling pathway via JAK-STAT biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007259 Wikipedia:JAK-STAT_signaling_pathway JAK-STAT signal transduction|JAK-STAT cascade Any process in which STAT proteins (Signal Transducers and Activators of Transcription) and JAK (Janus Activated Kinase) proteins convey a signal to trigger a change in the activity or state of a cell. The receptor signaling pathway via JAK-STAT begins with activation of a receptor and proceeeds through STAT protein activation by members of the JAK family of tyrosine kinases. STAT proteins dimerize and subsequently translocate to the nucleus. The pathway ends with regulation of target gene expression by STAT proteins. CHEBI:84649 O-[(5Z)-tetradecenoyl]-L-carnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84649 GO:0046822 regulation of nucleocytoplasmic transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046822 Any process that modulates the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm. GO:0007258 JUN phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007258 The process of introducing a phosphate group into a JUN protein. GO:0046821 extrachromosomal DNA biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0046821 Wikipedia:Extrachromosomal_DNA DNA structures that are not part of a chromosome. GO:0007257 activation of JUN kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007257 activation of SAPK activity The initiation of the activity of the inactive enzyme JUN kinase (JNK). GO:0046820 4-amino-4-deoxychorismate synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046820 EC:2.6.1.85|RHEA:11672|MetaCyc:PABASYN-RXN|KEGG_REACTION:R01716 chorismate:L-glutamine amido-ligase activity|p-aminobenzoate synthetase|para-aminobenzoic acid synthase activity|PabB activity|ADC synthase activity|aminodeoxychorismate synthase activity|para-aminobenzoic acid (PABA) synthase Catalysis of the reaction: L-glutamine + chorismate = 4-amino-4-deoxychorismate + L-glutamate. It is composed of two enzymatic activities (which may be present on one or two polypeptides); the first is a glutaminase which yields ammonia from glutamine, releasing glutamate. The ammonia is used by the second activity which catalyzes the amination of chorismate to form 4-amino-4-deoxychorismate. CHEBI:84647 O-[(9Z)-tetradecenoyl]-L-carnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84647 GO:0007256 activation of JNKK activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007256 positive regulation of JUNKK activity|activation of JUN kinase kinase activity The initiation of the activity of the inactive enzyme JUN kinase kinase (JNKK) activity. JNKKs are involved in a signaling pathway that is primarily activated by cytokines and exposure to environmental stress. GO:0007255 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007255 CHEBI:84645 (R)-icosanoylcarnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84645 GO:0007254 JNK cascade biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007254 MAPK10 cascade|JNK3 cascade|JNK2 cascade|JNK1 cascade|MAPK9 cascade|MAPK8 cascade|SAPK cascade|stress-activated protein kinase cascade|c-Jun N-terminal kinase cascade An intracellular protein kinase cascade containing at least a JNK (a MAPK), a JNKK (a MAPKK) and a JUN3K (a MAP3K). The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell. GO:0007253 cytoplasmic sequestering of NF-kappaB biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007253 cytoplasmic storage of NF-kappaB|cytoplasmic retention of NF-kappaB|maintenance of NF-kappaB location in cytoplasm|cytoplasmic NF-kappaB retention|cytoplasmic NF-kappaB storage|cytoplasmic sequestration of NF-kappaB|cytoplasmic NF-kappaB sequestration The selective interaction of the transcription factor NF-kappaB with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus. CHEBI:84644 O-octadecanoyl-L-carnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84644 GO:0007252 I-kappaB phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007252 IkappaB phosphorylation|IKB phosphorylation|inhibitor of NF-kappaB phosphorylation|inhibitor of kappaB phosphorylation The process of introducing a phosphate group into an inhibitor of kappa B (I-kappaB) protein. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing bound NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription. GO:0007251 obsolete activation of the inhibitor of kappa kinase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007251 activation of the inhibitor of kappa kinase OBSOLETE. (Was not defined before being made obsolete). GO:0007261 obsolete JAK-induced STAT protein dimerization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007261 JAK-induced STAT protein dimerization OBSOLETE. The formation of a dimer of two STAT proteins (Signal Transducers and Activators of Transcription) following their activation by members of the janus activated kinase (JAK) family of tyrosine kinases. GO:0007260 tyrosine phosphorylation of STAT protein biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007260 tyrosine phosphorylation of Stat7 protein|tyrosine phosphorylation of Stat6 protein|tyrosine phosphorylation of Stat5 protein|tyrosine phosphorylation of Stat4 protein|tyrosine phosphorylation of Stat3 protein|tyrosine phosphorylation of Stat2 protein|tyrosine phosphorylation of Stat1 protein The process of introducing a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein. GO:0046829 negative regulation of RNA import into nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046829 down-regulation of RNA import into nucleus|negative regulation of RNA import into cell nucleus|inhibition of RNA import into nucleus|negative regulation of RNA transport from cytoplasm to nucleus|down regulation of RNA import into nucleus|downregulation of RNA import into nucleus|negative regulation of RNA-nucleus import Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of RNA from the cytoplasm into the nucleus. GO:0046828 regulation of RNA import into nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046828 regulation of RNA transport from cytoplasm to nucleus|regulation of RNA-nucleus import|regulation of RNA import into cell nucleus Any process that modulates the frequency, rate or extent of movement of RNA from the cytoplasm to the nucleus. CHEBI:60687 cembrane diterpenoid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60687 GO:0046827 positive regulation of protein export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046827 positive regulation of protein export from cell nucleus|up regulation of protein export from nucleus|activation of protein export from nucleus|positive regulation of protein export out of nucleus|stimulation of protein export from nucleus|up-regulation of protein export from nucleus|positive regulation of protein-nucleus export|positive regulation of protein transport from nucleus to cytoplasm|upregulation of protein export from nucleus Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm. GO:0046826 negative regulation of protein export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046826 down-regulation of protein export from nucleus|negative regulation of protein export out of nucleus|negative regulation of protein-nucleus export|inhibition of protein export from nucleus|down regulation of protein export from nucleus|negative regulation of protein transport from nucleus to cytoplasm|negative regulation of protein export from cell nucleus|downregulation of protein export from nucleus Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the nucleus into the cytoplasm. CHEBI:60689 cembrane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60689 GO:0046825 regulation of protein export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046825 regulation of protein export from cell nucleus|regulation of protein transport from nucleus to cytoplasm|regulation of protein-nucleus export|regulation of protein export out of nucleus Any process that modulates the frequency, rate or extent of the directed movement of proteins from the nucleus to the cytoplasm. GO:0046824 positive regulation of nucleocytoplasmic transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046824 up-regulation of nucleocytoplasmic transport|upregulation of nucleocytoplasmic transport|up regulation of nucleocytoplasmic transport|activation of nucleocytoplasmic transport|stimulation of nucleocytoplasmic transport Any process that activates or increases the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm. GO:0046823 negative regulation of nucleocytoplasmic transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046823 inhibition of nucleocytoplasmic transport|down regulation of nucleocytoplasmic transport|downregulation of nucleocytoplasmic transport|down-regulation of nucleocytoplasmic transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances between the cytoplasm and the nucleus. GO:0032214 negative regulation of telomere maintenance via semi-conservative replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032214 downregulation of telomere maintenance via semi-conservative replication|down regulation of telomere maintenance via semi-conservative replication|inhibition of telomere maintenance via semi-conservative replication|down-regulation of telomere maintenance via semi-conservative replication Any process that stops, prevents, or reduces the frequency, rate or extent of the semi-conservative replication of telomeric DNA. GO:0032213 regulation of telomere maintenance via semi-conservative replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032213 Any process that modulates the frequency, rate or extent of the semi-conservative replication of telomeric DNA. GO:0022898 regulation of transmembrane transporter activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022898 Any process that modulates the frequency, rate or extent of transmembrane transporter activity. GO:0032212 positive regulation of telomere maintenance via telomerase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032212 up-regulation of telomere maintenance via telomerase activity|up regulation of telomere maintenance via telomerase activity|activation of telomere maintenance via telomerase|stimulation of telomere maintenance via telomerase|upregulation of telomere maintenance via telomerase activity Any process that activates or increases the frequency, rate or extent of the addition of telomeric repeats by telomerase. GO:0032211 negative regulation of telomere maintenance via telomerase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032211 inhibition of telomere maintenance via telomerase|down-regulation of telomere maintenance via telomerase activity|downregulation of telomere maintenance via telomerase activity|down regulation of telomere maintenance via telomerase activity Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of telomeric repeats by telomerase. GO:0032210 regulation of telomere maintenance via telomerase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032210 Any process that modulates the frequency, rate or extent of the addition of telomeric repeats by telomerase. GO:1900903 negative regulation of hexadecanal biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900903 inhibition of hexadecanal synthesis|negative regulation of hexadecanal formation|down-regulation of hexadecanal formation|inhibition of hexadecanal formation|down regulation of palmitaldehyde biosynthesis|down regulation of palmitaldehyde biosynthetic process|downregulation of palmitaldehyde biosynthetic process|downregulation of palmitaldehyde biosynthesis|down regulation of hexadecanal anabolism|down-regulation of hexadecanal biosynthetic process|down regulation of hexadecanal synthesis|downregulation of hexadecanal anabolism|down-regulation of hexadecanal biosynthesis|negative regulation of hexadecanal biosynthesis|down regulation of hexadecanal formation|negative regulation of palmitaldehyde biosynthesis|negative regulation of palmitaldehyde biosynthetic process|down-regulation of palmitaldehyde biosynthetic process|down-regulation of palmitaldehyde biosynthesis|downregulation of hexadecanal synthesis|downregulation of hexadecanal biosynthetic process|inhibition of palmitaldehyde biosynthesis|inhibition of palmitaldehyde biosynthetic process|downregulation of hexadecanal formation|negative regulation of hexadecanal anabolism|down-regulation of hexadecanal anabolism|down regulation of hexadecanal biosynthetic process|downregulation of hexadecanal biosynthesis|inhibition of hexadecanal biosynthetic process|inhibition of hexadecanal biosynthesis|inhibition of hexadecanal anabolism|negative regulation of hexadecanal synthesis|down-regulation of hexadecanal synthesis|down regulation of hexadecanal biosynthesis Any process that stops, prevents or reduces the frequency, rate or extent of hexadecanal biosynthetic process. GO:0022880 protein-N(PI)-phosphohistidine-N-acetylglucosamine phosphotransferase system transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022880 N-acetylglucosamine PTS transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N-acetylglucosamine(out) = protein histidine + N-acetylglucosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. GO:1900902 regulation of hexadecanal biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900902 regulation of palmitaldehyde biosynthetic process|regulation of palmitaldehyde biosynthesis|regulation of hexadecanal anabolism|regulation of hexadecanal synthesis|regulation of hexadecanal formation|regulation of hexadecanal biosynthesis Any process that modulates the frequency, rate or extent of hexadecanal biosynthetic process. GO:0032209 positive regulation of telomere maintenance via recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032209 stimulation of telomere maintenance via recombination|up-regulation of telomere maintenance via recombination|activation of telomere maintenance via recombination|up regulation of telomere maintenance via recombination|upregulation of telomere maintenance via recombination Any process that activates or increases the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length. GO:1900905 regulation of hexadecanal metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900905 regulation of hexadecanal metabolism Any process that modulates the frequency, rate or extent of hexadecanal metabolic process. GO:0022882 protein-N(PI)-phosphohistidine-beta-glucoside phosphotransferase system transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022882 beta-glucoside PTS transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + beta-glucoside(out) = protein histidine + beta-glucoside phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. CHEBI:45075 7-cyano-7-deazaguanine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_45075 GO:0022881 protein-N(PI)-phosphohistidine-N-acetylgalactosamine phosphotransferase system transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022881 N-acetylgalactosamine PTS transporter activity Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N-acetylgalactosamine(out) = protein histidine + N-acetylgalactosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport. GO:1900904 positive regulation of hexadecanal biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900904 up-regulation of hexadecanal anabolism|upregulation of hexadecanal biosynthesis|up-regulation of hexadecanal synthesis|upregulation of palmitaldehyde biosynthesis|upregulation of palmitaldehyde biosynthetic process|activation of hexadecanal biosynthetic process|up-regulation of hexadecanal biosynthetic process|activation of hexadecanal biosynthesis|up-regulation of hexadecanal formation|upregulation of hexadecanal anabolism|activation of palmitaldehyde biosynthesis|up-regulation of hexadecanal biosynthesis|upregulation of hexadecanal synthesis|up regulation of palmitaldehyde biosynthetic process|up regulation of palmitaldehyde biosynthesis|activation of hexadecanal anabolism|upregulation of hexadecanal formation|positive regulation of palmitaldehyde biosynthetic process|positive regulation of palmitaldehyde biosynthesis|up regulation of hexadecanal biosynthetic process|activation of hexadecanal synthesis|up regulation of hexadecanal anabolism|positive regulation of hexadecanal anabolism|positive regulation of hexadecanal biosynthesis|activation of palmitaldehyde biosynthetic process|activation of hexadecanal formation|up regulation of hexadecanal biosynthesis|up regulation of hexadecanal synthesis|positive regulation of hexadecanal synthesis|up regulation of hexadecanal formation|up-regulation of palmitaldehyde biosynthesis|up-regulation of palmitaldehyde biosynthetic process|positive regulation of hexadecanal formation|upregulation of hexadecanal biosynthetic process Any process that activates or increases the frequency, rate or extent of hexadecanal biosynthetic process. GO:0032208 negative regulation of telomere maintenance via recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032208 down-regulation of telomere maintenance via recombination|downregulation of telomere maintenance via recombination|down regulation of telomere maintenance via recombination|inhibition of telomere maintenance via recombination Any process that stops, prevents, or reduces the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length. GO:0022884 macromolecule transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022884 Enables the transfer of a macromolecule from one side of a membrane to the other. GO:0032207 regulation of telomere maintenance via recombination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032207 Any process that modulates the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length. GO:0032206 positive regulation of telomere maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032206 upregulation of telomere maintenance|stimulation of telomere maintenance|up-regulation of telomere maintenance|activation of telomere maintenance|up regulation of telomere maintenance Any process that activates or increases the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA. GO:0022883 zinc efflux transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022883 zinc efflux permease activity Enables the transfer of a zinc ion or zinc ions from the inside of the cell to the outside of the cell across a membrane. GO:0032205 negative regulation of telomere maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032205 inhibition of telomere maintenance|down-regulation of telomere maintenance|downregulation of telomere maintenance|down regulation of telomere maintenance Any process that stops, prevents, or reduces the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA. GO:1900901 positive regulation of heptadecane metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900901 up regulation of heptadecane metabolic process|activation of heptadecane metabolic process|upregulation of heptadecane metabolism|activation of heptadecane metabolism|up-regulation of heptadecane metabolic process|up-regulation of heptadecane metabolism|upregulation of heptadecane metabolic process|positive regulation of heptadecane metabolism|up regulation of heptadecane metabolism Any process that activates or increases the frequency, rate or extent of heptadecane metabolic process. GO:0022886 channel-forming ionophore activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022886 ionophore activity Enables transport of a solute across a membrane. This kind of transporter interacts much more weakly with the solute than the carrier does. It is an aqueous pore that extends across the membrane. It may change from closed to open and back. It transports faster than a carrier. It is always passive. GO:1900900 negative regulation of heptadecane metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900900 down regulation of heptadecane metabolism|down-regulation of heptadecane metabolic process|inhibition of heptadecane metabolic process|negative regulation of heptadecane metabolism|down-regulation of heptadecane metabolism|down regulation of heptadecane metabolic process|downregulation of heptadecane metabolic process|inhibition of heptadecane metabolism|downregulation of heptadecane metabolism Any process that stops, prevents or reduces the frequency, rate or extent of heptadecane metabolic process. GO:0022885 bacteriocin transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022885 Enables the transfer of a bacteriocin from one side of a membrane to the other. GO:0032204 regulation of telomere maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032204 Any process that modulates the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA. GO:0007269 neurotransmitter secretion biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0007269 neurotransmitter secretory pathway|neurotransmitter release The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium-regulated exocytosis during synaptic transmission. GO:0046833 positive regulation of RNA export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046833 positive regulation of RNA transport from nucleus to cytoplasm|upregulation of RNA export from nucleus|up regulation of RNA export from nucleus|positive regulation of RNA export from cell nucleus|activation of RNA export from nucleus|positive regulation of RNA export out of nucleus|stimulation of RNA export from nucleus|up-regulation of RNA export from nucleus|positive regulation of RNA-nucleus export Any process that activates or increases the frequency, rate or extent of directed movement of RNA from the nucleus into the cytoplasm. GO:0007268 chemical synaptic transmission biolink:BiologicalProcess go-plus goslim_synapse http://purl.obolibrary.org/obo/GO_0007268 Wikipedia:Neurotransmission neurotransmission|synaptic transmission|signal transmission across a synapse The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. GO:0046832 negative regulation of RNA export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046832 down regulation of RNA export from nucleus|negative regulation of RNA transport from nucleus to cytoplasm|downregulation of RNA export from nucleus|negative regulation of RNA export from cell nucleus|down-regulation of RNA export from nucleus|negative regulation of RNA export out of nucleus|inhibition of RNA export from nucleus|negative regulation of RNA-nucleus export Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of RNA from the nucleus into the cytoplasm. CHEBI:60690 nitrogen-containing fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60690 GO:0007267 cell-cell signaling biolink:BiologicalProcess go-plus goslim_plant|goslim_generic|goslim_chembl http://purl.obolibrary.org/obo/GO_0007267 cell-cell signalling Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions. GO:0046831 regulation of RNA export from nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046831 regulation of RNA-nucleus export|regulation of RNA export out of nucleus|regulation of RNA export from cell nucleus|regulation of RNA transport from nucleus to cytoplasm Any process that modulates the frequency, rate or extent of the directed movement of RNA from the nucleus to the cytoplasm. GO:0007266 Rho protein signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007266 Rho mediated signal transduction A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state. GO:0046830 positive regulation of RNA import into nucleus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046830 up regulation of RNA import into nucleus|activation of RNA import into nucleus|stimulation of RNA import into nucleus|positive regulation of RNA-nucleus import|positive regulation of RNA import into cell nucleus|up-regulation of RNA import into nucleus|positive regulation of RNA transport from cytoplasm to nucleus|upregulation of RNA import into nucleus Any process that activates or increases the frequency, rate or extent of movement of RNA from the cytoplasm into the nucleus. GO:0007265 Ras protein signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007265 Ras mediated signal transduction A series of molecular signals within the cell that are mediated by a member of the Ras superfamily of proteins switching to a GTP-bound active state. CHEBI:84656 alpha-Neu5Ac-(2->3)-beta-D-Gal(1->3)beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1->1')-Cer(d18:1/18:0) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84656 GO:0007264 small GTPase mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007264 small GTPase-mediated signal transduction Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals. CHEBI:60691 aza fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60691 GO:0007263 nitric oxide mediated signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007263 NO-mediated signal transduction|NO mediated signal transduction|nitric oxide-mediated signal transduction|nitric oxide signaling Any intracellular signal transduction in which the signal is passed on within the cell via nitric oxide (NO). Includes synthesis of nitric oxide, receptors/sensors for nitric oxide (such as soluble guanylyl cyclase/sGC) and downstream effectors that further transmit the signal within the cell. Nitric oxide transmits its downstream effects through either cyclic GMP (cGMP)-dependent or independent mechanisms. CHEBI:84654 (R)-4,8-dimethylnonanoylcarnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84654 GO:0007262 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007262 GO:0007272 ensheathment of neurons biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007272 ionic insulation of neurons by glial cells The process in which glial cells envelop neuronal cell bodies and/or axons to form an insulating layer. This can take the form of myelinating or non-myelinating ensheathment. GO:0007271 synaptic transmission, cholinergic biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007271 cholinergic synaptic transmission The vesicular release of acetylcholine from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. CHEBI:84651 (R)-oleoylcarnitine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84651 CHEBI:84650 (5Z)-tetradecenoyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84650 GO:0007270 neuron-neuron synaptic transmission biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007270 nerve-nerve synaptic transmission The process of synaptic transmission from a neuron to another neuron across a synapse. GO:0046839 phospholipid dephosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046839 The process of removing one or more phosphate groups from a phosphorylated lipid, any member of a group of substances soluble in lipid solvents but only sparingly soluble in aqueous solvents. GO:0046838 phosphorylated carbohydrate dephosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046838 The process of removing a phosphate group from a phosphorylated carbohydrate, any organic compound based on the general formula Cx(H2O)y with a phosphate group attached to it. GO:0046837 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046837 GO:0046836 glycolipid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046836 The directed movement of glycolipids, compounds containing (usually) 1-4 linked monosaccharide residues joined by a glycosyl linkage to a lipid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0046835 carbohydrate phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046835 The process of introducing a phosphate group into a carbohydrate, any organic compound based on the general formula Cx(H2O)y. GO:0046834 lipid phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046834 The process of introducing one or more phosphate groups into a lipid, any member of a group of substances soluble in lipid solvents but only sparingly soluble in aqueous solvents. GO:0032203 telomere formation via telomerase biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032203 A cellular process that results in the formation of a telomere at a non-telomeric double-stranded DNA end that involves the activity of a telomerase enzyme. GO:0032202 telomere assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032202 telomere formation A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a telomere at a non-telomeric double-stranded DNA end. A telomere is a terminal region of a linear chromosome that includes telomeric DNA repeats and associated proteins. GO:0032201 telomere maintenance via semi-conservative replication biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032201 telomeric replication fork progression|equal telomere replication|telomeric fork progression The process in which telomeric DNA is synthesized semi-conservatively by the conventional replication machinery and telomeric accessory factors as part of cell cycle DNA replication. GO:0032200 telomere organization biolink:BiologicalProcess go-plus goslim_pombe|goslim_yeast http://purl.obolibrary.org/obo/GO_0032200 organization of chromosome, telomeric region|telomere organisation|chromosome organization, telomeric|telomere organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of telomeres, terminal regions of a linear chromosome that include the telomeric DNA repeats and associated proteins. GO:0022889 serine transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0022889 Enables the transfer of serine from one side of a membrane to the other. Serine is 2-amino-3-hydroxypropanoic acid. GO:1900907 positive regulation of hexadecanal metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900907 up regulation of hexadecanal metabolic process|upregulation of hexadecanal metabolism|activation of hexadecanal metabolic process|activation of hexadecanal metabolism|up-regulation of hexadecanal metabolism|up-regulation of hexadecanal metabolic process|positive regulation of hexadecanal metabolism|upregulation of hexadecanal metabolic process|up regulation of hexadecanal metabolism Any process that activates or increases the frequency, rate or extent of hexadecanal metabolic process. GO:1900906 negative regulation of hexadecanal metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900906 downregulation of hexadecanal metabolic process|down regulation of hexadecanal metabolism|inhibition of hexadecanal metabolism|down-regulation of hexadecanal metabolic process|inhibition of hexadecanal metabolic process|negative regulation of hexadecanal metabolism|down-regulation of hexadecanal metabolism|downregulation of hexadecanal metabolism|down regulation of hexadecanal metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of hexadecanal metabolic process. GO:1900909 negative regulation of olefin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900909 down-regulation of olefin metabolic process|down-regulation of olefin metabolism|negative regulation of olefin metabolism|downregulation of olefin metabolic process|down regulation of olefin metabolic process|inhibition of olefin metabolism|inhibition of olefin metabolic process|down regulation of olefin metabolism|downregulation of olefin metabolism Any process that stops, prevents or reduces the frequency, rate or extent of olefin metabolic process. GO:1900908 regulation of olefin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900908 regulation of olefin metabolism Any process that modulates the frequency, rate or extent of olefin metabolic process. GO:0140104 molecular carrier activity biolink:MolecularActivity go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0140104 Directly binding to a specific ion or molecule and delivering it either to an acceptor molecule or to a specific location. GO:0140103 catalytic activity, acting on a glycoprotein biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140103 Catalysis of a biochemical reaction at physiological temperatures in which one of the substrates is a glycoprotein. CHEBI:3828 (R)-columbianetin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_3828 GO:0140105 interleukin-10-mediated signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140105 IL-10-mediated signaling pathway|interleukin-10-mediated signalling pathway A series of molecular signals initiated by the binding of interleukin-10 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GO:0140108 high-affinity glucose transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140108 Enables the transfer of glucose from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. GO:0140107 high-affinity potassium ion transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140107 Enables the transfer of potassium ions from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. UBERON:0002085 interatrial septum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002085 interatrial septal wall|atrial septum|atrium septum A cardiac septum that divides the left and right atria of the heart. UBERON:0002084 heart left ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002084 left ventricle|left cardiac ventricle|ventriculus sinister cordis|left ventricle of heart|cardiac left ventricle A cardiac ventricle that is in the left side of the heart. UBERON:0002087 atrioventricular canal biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002087 canalis atrioventricularis|atrio-ventricular canal|atrial canal|AV canal|AVC|ependymal canal The part of the heart connecting the atrium to the cardiac ventricle[ZFA]. In the developing heart, the constriction between the atrium and ventricle constitutes the atrial canal, and indicates the site of the future atrioventricular valves[WP]. UBERON:0002086 sinoatrial valve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002086 sinoatrial valves|sinuatrial valve A valve at the opening of the sinus venosus into the primordial atrium[TFD,modified] UBERON:0002081 cardiac atrium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002081 atria|cardiac atria|atrial tissue|atrium|heart atrium|atrium of heart Cardiac chamber in which blood enters the heart. UBERON:0002080 heart right ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002080 ventriculus dexter|right ventricle of heart|right ventricle|cardiac right ventricle|right cardiac ventricle A cardiac ventricle that is in the right side of the heart. GO:0140102 catalytic activity, acting on a rRNA biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140102 Catalytic activity that acts to modify a ribosomal RNA. UBERON:0002082 cardiac ventricle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002082 heart ventricle|ventricle of heart|ventricle|lower chamber of heart Cardiac chamber through which blood leaves the heart. GO:0140101 catalytic activity, acting on a tRNA biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140101 Catalytic activity that acts to modify a tRNA. UBERON:0002089 thoracodorsal vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002089 companion vein of the thoracodorsal artery, draining the apical part of the latissimus dorsi and merging with the circumflex scapular vein to form a subscapular vein NCBITaxon:32443 Teleostei organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_32443 teleost fishes UBERON:0002074 hair shaft biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002074 shaft of hair|scapus pili The main part of the hair which is composed of trichocytes and is divided into the cortex and medulla. UBERON:0002073 hair follicle biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002073 folliculus pili A tube-like opening in the epidermis where the hair shaft develops and into which the sebaceous glands open[GO]. UBERON:0002076 cuticle of hair biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002076 hair cuticle smooth and glossy outer protective cell layer of hair shaft CHEBI:3830 camphene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_3830 UBERON:0002075 viscus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002075 viscera|visceral organ|visceral tissue|visceral organ system|Organsystem@de|splanchnic tissue An organ that is located within the body cavity (or in its extension, in the scrotum); it consists of organ parts that are embryologically derived from endoderm, splanchnic mesoderm or intermediate mesoderm; together with other organs, the viscus constitutes the respiratory, gastrointestinal, urinary, reproductive and immune systems, or is the central organ of the cardiovascular system. Examples: heart, lung, esophagus, kidney, ovary, spleen. UBERON:0002072 hypodermis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002072 hypoderm|sub-tegumental tissue|subcutaneous tissue|vertebrate hypodermis|subcutis|tela subcutanea|subtegumental tissue|superficial fascia Lowermost layer of the integumentary system in vertebrates. Types of cells that are found in the hypodermis are fibroblasts, adipose cells, and macrophages. It is derived from the mesoderm, but unlike the dermis, it is not derived from the dermatome region of the mesoderm. The hypodermis is used mainly for fat storage[WP]. UBERON:0002078 right cardiac atrium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002078 cardiac right atrium|right cardiac atrium|atrium dextrum|right atrium|heart right atrium|right atrium of heart A cardiac atrium that is in the left side of the heart. It receives deoxygenated blood. In mammals, this comes from the superior and inferior vena cava and the coronary sinus, and pumps it into the right ventricle through the tricuspid valve. UBERON:0002077 cortex of hair biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002077 coat/hair cortex|cortex of coat/hair|hair cortex|coat hair cortex|cortex of coat hair A cortex that is part of a hair [Automatically generated definition]. UBERON:0002079 left cardiac atrium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002079 left atrium of heart|heart left atrium|left cardiac atrium|left atrium|atrium sinistrum|cardiac left atrium A cardiac atrium that is in the left side of the heart. It receives oxygenated blood from the pulmonary veins, In mammals this is pumped into the left ventricle, via the Mitral valve. GO:0140125 thiamine import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140125 The directed movement of thiamine from outside of a cell, across the plasma membrane and into the cytosol. UBERON:0002063 sinus venosus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002063 inflow tract|venosus|sinus venarum|venarum sinus|sinus venosus cordis|venarum The sinus venosus is a large cardiac chamber at the inflow tract that receives venous blood from systemic circulation. precedes the atrium on the venous side of the chordate heart. UBERON:0002062 endocardial cushion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002062 endocardial cushions|cardiac cushion|atrioventricular cushion|AV cushion|endocardial cushion tissue|atrioventricular canal cushion The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves[GO]. Swellings of tissue present between the endocardial and myocardial cell layers that will give rise to the interstitial cells of the cardiac valves[ZFA]. GO:0140122 regulation of Lewy body formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140122 Any process that modulates the frequency, rate or extent of Lewy body formation. GO:0140121 Lewy body formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140121 The aggregation, arrangement and bonding together of a set of components to form a Lewy body. GO:0140124 positive regulation of Lewy body formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140124 Any process that activates or increases the frequency, rate or extent of Lewy body formation. UBERON:0002061 truncus arteriosus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002061 The truncus arteriosus and bulbus cordis are divided by the aorticopulmonary septum. The truncus arteriosus gives rise to the ascending aorta and the pulmonary trunk. The bulbus cordis gives rise to the smooth parts (outflow tract) of the left and right ventricles. UBERON:0002060 femoral artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002060 arteria femoralis The femoral artery is a large artery in the muscles of the thigh. It is a continuation of external iliac artery where it enters the femoral triangle at the mid inguinal point behind the inguinal ligament. It leaves femoral triangle through apex beneath the sartorius muscle. It enters the popliteal fossa by passing through the 5th osseo-aponeurotic(adductor hiatus) opening of adductor magnus where it becomes the Popliteal Artery. [WP,unvetted]. GO:0140123 negative regulation of Lewy body formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140123 Any process that stops, prevents or reduces the frequency, rate or extent of Lewy body formation. UBERON:0002067 dermis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002067 vertebrate dermis|corium|cutis The dermis is a layer of skin between the epidermis (with which it makes up the skin) and subcutaneous tissues, and is composed of two layers, the papillary and reticular dermis[WP]. GO:0140115 export across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140115 efflux The directed movement of some substance from inside of a cell, across the plasma membrane and into the extracellular region. GO:0140114 cellular detoxification of fluoride biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140114 Any process carried out at the cellular level that reduces or removes the toxicity of a fluoride. These may include transport of fluoride away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance. CHEBI:11614 2-methylbut-2-enoyl-coenzyme A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_11614 GO:0140116 fluoride export across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140116 The directed movement of fluoride ions from inside of a cell, across the plasma membrane and into the extracellular region. UBERON_CORE:extends_fibers_into extends_fibers_into biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/uberon/core#extends_fibers_into extends_fibers_into UBERON:0002052 adrenal gland capsule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002052 adrenal capsule|capsule of adrenal gland the thick capsule of dense irregular connective tissue that surrounds each adrenal gland and contains scattered elastic fibers; the capsule contains a rich plexus of blood vessels (mainly small arteries) and numerous nerve fibers; some blood vessels and nerves enter the substance of the gland in the trabeculae that extend inward from the capsule and then leave the trabeculae to enter the cortex. UBERON:0002051 epithelium of bronchiole biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002051 epithelial tissue of bronchiole|bronchiolar epithelium|epithelial tissue of lobular bronchiole|epithelium of lobular bronchiole|bronchiole epithelial tissue|lobular bronchiole epithelium|lobular bronchiole epithelial tissue|bronchiole epithelium An epithelium that is part of a bronchiole [Automatically generated definition]. GO:0140111 [choline trimethylamine-lyase]-activating enzyme activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140111 MetaCyc:RXN-16470 Catalyzes the activation of choline trimethylamine-lyase by generation of an organic free radical on a glycine residue via a homolytic cleavage of S-adenosyl-L-methionine (SAM). GO:0140110 transcription regulator activity biolink:MolecularActivity go-plus gocheck_do_not_annotate|goslim_plant|goslim_flybase_ribbon http://purl.obolibrary.org/obo/GO_0140110 A molecular function that controls the rate, timing and/or magnitude of gene transcription. The function of transcriptional regulators is to modulate gene expression at the transcription step so that they are expressed in the right cell at the right time and in the right amount throughout the life of the cell and the organism. Genes are transcriptional units, and include bacterial operons. GO:0140113 extracellular microvesicle biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140113 extracellular microvesicle assembly The assembly and secretion of a set of components to form an extracellular microvesicule, a membrane-bounded vesicle that ranges in size 100 nm to 1 micron in size) and exits the cell by budding. UBERON:0002050 embryonic structure biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002050 embryonale Struktur|embryonic structures|embryonic anatomical structure|developing structure|developing embryonic structure Anatomical structure that is part of an embryo. GO:0140112 extracellular vesicle biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140112 extracellular vesicle assembly The assembly and secretion a set of components to form an extracellular vesicule, a membrane-bounded vesicle that is released into the extracellular region. Extracellular vesicles include exosomes, microvesicles and apoptotic bodies, based on the mechanism by which they are released from cells and differentiated based on their size and content. UBERON:0002059 submandibular ganglion biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002059 maxillary ganglion|submaxillary ganglion|ganglion submandibulare|Blandin`s ganglion|mandibular ganglion|lingual ganglion the ganglion associated with the lingual nerve that provides postsynaptic fibers to the submandibular and sublingual glands UBERON:0002056 inferior suprarenal artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002056 arteria suprarenalis inferior Each renal artery gives off some small inferior suprarenal branches to the suprarenal gland, the ureter, and the surrounding cellular tissue and muscles. [WP,unvetted]. UBERON:0002057 phrenic artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002057 An artery that supplies the diaphragm GO:0032195 post-lysosomal vacuole biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032195 post-lysosome A membrane-bounded intracellular vesicle formed late in the endocytic pathway when the pH in the vacuole becomes neutral prior to exocytosis. GO:0032194 ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032194 The chemical reactions and pathways resulting in the formation of ubiquinone, via the intermediates 3,4-dihydroxy-5-polyprenylbenzoate and 3-methoxy-4-hydroxy-5-polyprenylbenzoate. GO:0032193 ubiquinone biosynthetic process via 2-polyprenylphenol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032193 The chemical reactions and pathways resulting in the formation of ubiquinone, via the intermediates 2-polyprenylphenol and 2-polyprenyl-6-hydroxyphenol. GO:0032192 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032192 GO:0032191 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032191 GO:0032190 acrosin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032190 acrosin light chain binding|acrosin heavy chain binding Interacting selectively and non-covalently with acrosin, a protein that is found in the acrosomes of sperm and possesses protease and carbohydrate binding activities. UBERON_CORE:sexually_homologous_to sexually_homologous_to biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/uberon/core#sexually_homologous_to sexually_homologous_to GO:0032199 reverse transcription involved in RNA-mediated transposition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032199 reverse transcription during retrotransposition The synthesis of DNA from an RNA transposon intermediate. GO:0032198 MITE transposition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032198 Class III transposition Any process involved in the transposition of miniature inverted-repeat transposable elements (MITEs). GO:0032197 transposition, RNA-mediated biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032197 Wikipedia:Transposon##Class_I:_Retrotransposons Tf transposition|Ty3 element transposition|Ty2 element transposition|Ty1 element transposition|retrotransposon transposition|Ty element transposition|RNA-mediated transposition|retrotransposition|Class I transposition Any process involved in a type of transpositional recombination which occurs via an RNA intermediate. GO:0032196 transposition biolink:BiologicalProcess go-plus goslim_pir|goslim_aspergillus|goslim_generic|goslim_chembl|goslim_candida|goslim_yeast http://purl.obolibrary.org/obo/GO_0032196 Wikipedia:Transposon Any process involved in mediating the movement of discrete segments of DNA between nonhomologous sites. GO:0032184 SUMO polymer binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032184 Smt3 polymer binding Interacting selectively and non-covalently with a polymer of the small ubiquitin-like protein SUMO. GO:0032183 SUMO binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032183 Smt3 monomer binding|Smt3 binding Interacting selectively and non-covalently with the small ubiquitin-like protein SUMO. GO:0032182 ubiquitin-like protein binding biolink:MolecularActivity go-plus goslim_chembl|goslim_yeast|goslim_generic http://purl.obolibrary.org/obo/GO_0032182 small conjugating protein binding Interacting selectively and non-covalently with a small conjugating protein such as ubiquitin or a ubiquitin-like protein. GO:0032181 dinucleotide repeat insertion binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032181 Interacting selectively and non-covalently with double-stranded DNA containing a dinucleotide repeat insertion or a deletion resulting in unpaired dinucleotide repeats. GO:0032180 ubiquinone biosynthetic process from tyrosine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032180 The chemical reactions and pathways resulting in the formation of ubiquinone, beginning with the conversion of tyrosine to 4-hydroxybenzoate. GO:0032189 maintenance of actomyosin contractile ring localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032189 maintenance of contractile ring localization involved in cytokinesis during cell cycle|maintenance of contractile ring localisation involved in cell cycle cytokinesis|maintenance of contractile ring localization involved in cell cycle cytokinesis|cytokinetic ring anchoring Any process in which an actomyosin contractile ring is maintained in a location and prevented from moving elsewhere. GO:0032188 establishment of actomyosin contractile ring localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032188 establishment of contractile ring localisation involved in cell cycle cytokinesis|establishment of contractile ring localization involved in cytokinesis during cell cycle|establishment of contractile ring localization involved in cell cycle cytokinesis|actomyosin ring positioning|cytokinesis site selection by contractile ring positioning|contractile ring positioning The process in which a contractile ring is assembled in a specific location as part of a process of cell cycle cytokinesis. GO:0032187 actomyosin contractile ring localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032187 contractile ring localisation involved in cell cycle cytokinesis|contractile ring localization involved in cell cycle cytokinesis The process in which a contractile ring is assembled and/or maintained in a specific location, in the context of cytokinesis that takes place as part of a cell cycle. GO:0032186 cellular bud neck septin ring organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032186 cellular bud neck septin ring organisation Control of the formation, spatial distribution, and breakdown of a septin ring located at the bud neck. GO:0032185 septin cytoskeleton organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032185 septin cytoskeleton organisation|septin cytoskeleton organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising septin complexes and their associated proteins. GO:0032173 septin collar biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032173 septin hourglass A tubular, hourglass-shaped structure composed of highly ordered arrays of septin filaments; in budding yeast cells, the septin collar forms from the initial septin ring by expanding into the daughter cell. GO:0032172 germ tube septin ring biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032172 A tight ring-shaped structure that forms in the division plane within the germ tube of filamentous fungi at sites where a septum will form; composed of septins as well as septin-associated proteins. GO:0032171 germ tube septin cap biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032171 A faint structure formed of septins found at the leading edge of growth in germ tubes of fungal cells growing filamentously. This cap of septins colocalizes with a region of the plasma membrane that is rich in ergosterol. GO:0032170 pseudohyphal septin ring biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032170 A tight ring-shaped structure that forms in the division plane at the junction between the mother cell and a pseudohyphal projection; composed of septins as well as septin-associated proteins. GO:0032179 germ tube biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0032179 Wikipedia:Germ_tube The slender tubular outgrowth first produced by most spores in germination. CHEBI:60606 opioid receptor agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60606 GO:0032178 medial membrane band biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032178 sterol-rich membrane band A sterol-rich region of the plasma membrane which forms at the cell surface overlying the contractile ring and spreads into the invaginating plasma membrane surrounding the septum. GO:0032177 cellular bud neck split septin rings biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032177 Two separate septin rings that are formed from the septin collar at the time of cytokinesis in cells that divide by budding. These two rings are thought to delineate a special compartment in which factors involved in cytokinesis are concentrated. GO:0032176 split septin rings biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032176 A pair of rings that flank the site of cell division, formed by splitting of the septin ring (or collar) prior to cytokinesis; this double ring structure is thought to trap proteins needed for cytokinesis or the formation of the new membrane or cell wall between the two septin rings. Split septin rings are known to occur in budding yeast cells and probably occur in other cell types as well. GO:0032175 mating projection septin ring biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032175 A septin ring, i.e. a ring-shaped structure composed of septins and septin-associated proteins, located at the neck of a shmoo (mating projection). The septin ring in the neck of a shmoo may act as a barrier to localize mating factors in the shmoo tip. GO:0032174 cellular bud neck septin collar biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032174 A tubular structure with flared ends, shaped like an hourglass and composed of highly ordered arrays of septin filaments, that forms at the bud neck of a dividing cell. In S. cerevisiae, this structure is located at the bud neck throughout most of the cell cycle and the septins are fixed within the structure, not exchanging with soluble septins. This septin structure acts as a scaffold for other proteins that function at the bud neck. UBERON:0002090 postcranial axial skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002090 axial skeleton|post-cranial axial skeleton The postcranial subdivision of skeleton structural components forming the long axis of the vertebrate body; in Danio, consisting of the notochord, vertebrae, ribs, supraneurals, intermuscular bones, and unpaired median fins; in human consists of the bones of the vertebral column, the thoracic cage and the pelvis[ZFA+FMA]. GO:0032162 mating projection septin band biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032162 A septin band, i.e. a diffuse ring composed of a series of septin bars running parallel to the long axis of the cell, located at the neck of a shmoo (mating projection). GO:0032161 cleavage apparatus septin structure biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032161 Any of a series of structures composed of septins and septin-associated proteins localized to the cleavage plane which are involved in cytokinesis. UBERON:0002095 mesentery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002095 mesentery (generic)|generic mesentery Anatomical organ component composed of a double layer of serous membrane that suspends a viscus from the body wall or connects adjacent viscera and in doing so conveys blood vessels, lymphatics and nerves to and from the viscera. Examples: greater omentum, broad ligament of uterus, sigmoid mesocolon. GO:0032160 septin filament array biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032160 septin bar Arrays of septin filaments, or bars, found in a series of filamentous structures. Such structures have been observed in the prospore membrane during spore formation in S. cerevisiae and in the chlamydospore membrane during chlamydospore formation in C. albicans. UBERON:0002097 skin of body biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002097 integument|integumental organ|pelt|skin|skin organ|entire skin|entire integument The organ covering the body that consists of the dermis and epidermis. UBERON:0002092 brain dura mater biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002092 dura mater encephali|dura mater of brain|cranial dura mater|dura mater cranialis The fibrous membrane forming the outer of the three coverings that surrounds the brain within the cranial cavity; consists of two layers including the periosteal layer and the meningeal layer. UBERON:0002091 appendicular skeleton biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002091 entire appendicular skeleton|appendicular skeleton|skeleton appendiculare|paired fin skeleton Subdivision of skeleton which which consists of all the skeletal elements in in the pectoral and pelvic appendage complexes[cjm]. UBERON:0002094 interventricular septum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002094 heart ventricular septum|intraventricular septum|septum inferius|s. interventriculare cordis|interventriculare cordis|ventricle septum|septum membranaceum|heart interventricular septum|interventricular septum of heart|ventricular septum Cardiac septum which separates the right ventricle from the left ventricle.[FMA] UBERON:0002093 spinal dura mater biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002093 dura mater of neuraxis of spinal cord|spinal cord dura mater|dura mater of spinal cord|spinal cord dura mater of neuraxis A dura mater that is part of a spinal cord [Automatically generated definition]. CHEBI:60615 N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-Asn residue biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60615 GO:0032169 prospore septin ring biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032169 A tight ring-shaped structure that forms in the division plane at the site of cytokinesis in a prospore; composed of septins as well as septin-associated proteins. GO:0032168 hyphal septin ring biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032168 A tight ring-shaped structure that forms in the division plane within hyphae of filamentous fungi at sites where a septum will form; composed of septins as well as septin-associated proteins. GO:0032167 obsolete septin patch biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032167 septin patch OBSOLETE. An amorphous-appearing accumulation of septin proteins at the future site of cytokinesis. GO:0032166 chlamydospore septin filament array biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032166 Arrays of septin filaments, or bars, found in a series of filamentous structures. Observed in the chlamydospore membrane during chlamydospore formation. UBERON:0002099 cardiac septum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002099 heart septum|cardiac septa|spiral septa|heart septa|septum of heart The thin membranous structure between the two heart atria or the thick muscular structure between the two heart ventricles. GO:0032165 prospore septin filament array biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032165 Arrays of septin filaments, or bars, found in a series of filamentous structures; observed in the prospore membrane during spore formation. GO:0032164 hyphal septin cap biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032164 A faint structure formed of septins found at the leading edge of growth in hyphae of fungal cells growing filamentously. This cap of septins colocalizes with a region of the plasma membrane that is rich in ergosterol. GO:0032163 hyphal septin band biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032163 A septin band, i.e. a diffuse ring composed of a series of septin bars running parallel to the long axis of the cell, located at the junction between the mother cell and the germ tube (hypha) of a fungal cell growing filamentously. CHEBI:21010 D-glucosyl-D-mannose biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21010 GO:1900877 nonadec-1-ene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900877 nonadec-1-ene formation|nonadec-1-ene biosynthesis|nonadec-1-ene anabolism|nonadec-1-ene synthesis The chemical reactions and pathways resulting in the formation of nonadec-1-ene. GO:1900876 nonadec-1-ene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900876 nonadec-1-ene metabolism The chemical reactions and pathways involving nonadec-1-ene. GO:1900879 (Z)-nonadeca-1,14-diene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900879 (Z)-nonadeca-1,14-diene anabolism|(Z)-nonadeca-1,14-diene synthesis|(Z)-nonadeca-1,14-diene biosynthesis|(Z)-nonadeca-1,14-diene formation The chemical reactions and pathways resulting in the formation of (Z)-nonadeca-1,14-diene. GO:1900878 (Z)-nonadeca-1,14-diene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900878 (Z)-nonadeca-1,14-diene metabolism The chemical reactions and pathways involving (Z)-nonadeca-1,14-diene. GO:1900873 pentadec-1-ene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900873 pentadec-1-ene anabolism|pentadec-1-ene synthesis|pentadec-1-ene formation|pentadec-1-ene biosynthesis The chemical reactions and pathways resulting in the formation of pentadec-1-ene. GO:1900872 pentadec-1-ene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900872 pentadec-1-ene metabolism The chemical reactions and pathways involving pentadec-1-ene. GO:1900875 heptadec-1-ene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900875 heptadec-1-ene anabolism|heptadec-1-ene synthesis|heptadec-1-ene formation|heptadec-1-ene biosynthesis The chemical reactions and pathways resulting in the formation of heptadec-1-ene. GO:1900874 heptadec-1-ene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900874 heptadec-1-ene metabolism The chemical reactions and pathways involving heptadec-1-ene. GO:1900871 chloroplast mRNA modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900871 chloroplast mRNA editing|mRNA editing in chloroplast The covalent alteration within the chloroplast of one or more nucleotides within an mRNA to produce an mRNA molecule with a sequence that differs from that coded genetically. GO:1900870 tatiopterin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900870 tatiopterin biosynthesis|tatiopterin anabolism|tatiopterin synthesis|tatiopterin formation The chemical reactions and pathways resulting in the formation of tatiopterin. CHEBI:11684 3,3',5'-triiodo-L-thyronine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_11684 UBERON:2000238 olfactory tract linking bulb to ipsilateral ventral telencephalon biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_2000238 GO:0071769 mycolate cell wall layer assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071769 MetaCyc:PWY-6397 mycolate cell wall layer biogenesis The aggregation, arrangement and bonding together of a set of components, including arabinogalactan mycolate and trehalose dimycolate, to form the mycolate layer of the Actinobacterium-type cell wall. The mycolate layer is physically attached to the peptidoglycan layer. GO:0071768 mycolic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071768 MetaCyc:PWYG-321 mycolic acid formation|mycolic acid biosynthesis|mycolate biosynthetic process|mycolic acid anabolism|mycolic acid synthesis The chemical reactions and pathways resulting in the formation of mycolic acids, beta-hydroxy fatty acids with a long alpha-alkyl side chain. GO:0071767 mycolic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071767 mycolate metabolic process|mycolic acid metabolism The chemical reactions and pathways involving mycolic acids, beta-hydroxy fatty acids with a long alpha-alkyl side chain. UBERON:0002005 enteric nervous system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002005 enteric PNS|PNS - enteric The enteric nervous system is composed of two ganglionated neural plexuses in the gut wall which form one of the three major divisions of the autonomic nervous system. The enteric nervous system innervates the gastrointestinal tract, the pancreas, and the gall bladder. It contains sensory neurons, interneurons, and motor neurons. Thus the circuitry can autonomously sense the tension and the chemical environment in the gut and regulate blood vessel tone, motility, secretions, and fluid transport. The system is itself governed by the central nervous system and receives both parasympathetic and sympathetic innervation[GO]. GO:0071766 Actinobacterium-type cell wall biogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071766 A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall of the type found in Actinobacteria. The cell wall is the rigid or semi-rigid envelope lying outside the cell membrane. Actinobacterial cell walls contain characteristic mycolic acids, of which some are covalently linked to the cell wall peptidoglycan and others accumulate at the cell surface. GO:0071765 nuclear inner membrane organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071765 nuclear inner membrane organization and biogenesis|nuclear inner membrane organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner membrane. UBERON:0002007 medulla of lymph node biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002007 medulla nodi lymphoidei|lymph node medulla The mdeullary portion of the lymph node, which contains large blood vessels, sinuses and medullary cords that contain antibody-secreting plasma cells. GO:0071764 nuclear outer membrane organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071764 nuclear outer membrane organisation|nuclear outer membrane organization and biogenesis A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear outer membrane. UBERON:0002006 cortex of lymph node biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002006 lymph node cortex|cortex nodi lymphoidei Peripheral portion of the lymph node, underneath the capsule[WP]. GO:0071763 nuclear membrane organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071763 nuclear membrane organization and biogenesis|nuclear membrane organisation A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner or outer membrane. UBERON:0002001 joint of rib biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002001 rib joint Any joint that connects a rib to another structure (or another rib). Examples: costochondral, costovertebral, interchondral, sternocostal joints. GO:0071762 heavy chain immunoglobulin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071762 IgNAR antibody|HCab|Ig NAR immunoglobulin complex|IgNAR immunoglobulin complex A protein complex composed of two identical immunoglobulin heavy chains of the IgNAR isotype held together by disulfide bonds and lacking immunoglobulin light chains. GO:0071761 IgZ immunoglobulin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071761 IgT immunoglobulin complex|IgT antibody|IgZ antibody A protein complex composed of two identical immunoglobulin heavy chains of the IgZ isotype and two identical immunoglobulin light chains, held together by disulfide bonds. The IgZ isotype is also known as the IgT isotype in certain species of fish. GO:0071760 IgY immunoglobulin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071760 A protein complex composed of two identical immunoglobulin heavy chains of the IgY isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgY immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. GO:1900888 negative regulation of pentadecane biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900888 down regulation of pentadecane biosynthetic process|downregulation of pentadecane biosynthesis|inhibition of pentadecane biosynthetic process|inhibition of pentadecane biosynthesis|down regulation of pentadecane anabolism|inhibition of pentadecane formation|down regulation of pentadecane biosynthesis|downregulation of pentadecane anabolism|down regulation of pentadecane synthesis|down regulation of pentadecane formation|downregulation of pentadecane synthesis|downregulation of pentadecane formation|negative regulation of pentadecane anabolism|down-regulation of pentadecane anabolism|down-regulation of pentadecane biosynthetic process|negative regulation of pentadecane synthesis|down-regulation of pentadecane synthesis|inhibition of pentadecane synthesis|negative regulation of pentadecane formation|down-regulation of pentadecane formation|down-regulation of pentadecane biosynthesis|negative regulation of pentadecane biosynthesis|inhibition of pentadecane anabolism|downregulation of pentadecane biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of pentadecane biosynthetic process. GO:1900887 regulation of pentadecane biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900887 regulation of pentadecane anabolism|regulation of pentadecane synthesis|regulation of pentadecane formation|regulation of pentadecane biosynthesis Any process that modulates the frequency, rate or extent of pentadecane biosynthetic process. GO:1900889 positive regulation of pentadecane biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900889 upregulation of pentadecane anabolism|upregulation of pentadecane biosynthetic process|upregulation of pentadecane synthesis|activation of pentadecane anabolism|upregulation of pentadecane formation|upregulation of pentadecane biosynthesis|up regulation of pentadecane anabolism|activation of pentadecane synthesis|activation of pentadecane biosynthetic process|up-regulation of pentadecane biosynthetic process|positive regulation of pentadecane anabolism|activation of pentadecane biosynthesis|activation of pentadecane formation|up regulation of pentadecane synthesis|positive regulation of pentadecane synthesis|up regulation of pentadecane formation|up-regulation of pentadecane biosynthesis|positive regulation of pentadecane formation|up-regulation of pentadecane anabolism|up regulation of pentadecane biosynthetic process|up-regulation of pentadecane synthesis|positive regulation of pentadecane biosynthesis|up regulation of pentadecane biosynthesis|up-regulation of pentadecane formation Any process that activates or increases the frequency, rate or extent of pentadecane biosynthetic process. GO:1900884 regulation of tridecane biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900884 regulation of tridecane formation|regulation of tridecane biosynthesis|regulation of tridecane anabolism|regulation of tridecane synthesis Any process that modulates the frequency, rate or extent of tridecane biosynthetic process. GO:1900883 17-methylnonadec-1-ene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900883 17-methylnonadec-1-ene anabolism|17-methylnonadec-1-ene biosynthesis|17-methylnonadec-1-ene synthesis|17-methylnonadec-1-ene formation The chemical reactions and pathways resulting in the formation of 17-methylnonadec-1-ene. GO:1900886 positive regulation of tridecane biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900886 activation of tridecane anabolism|positive regulation of tridecane anabolism|up regulation of tridecane synthesis|activation of tridecane synthesis|positive regulation of tridecane synthesis|up regulation of tridecane formation|upregulation of tridecane biosynthesis|upregulation of tridecane biosynthetic process|activation of tridecane formation|positive regulation of tridecane formation|up-regulation of tridecane anabolism|up-regulation of tridecane synthesis|up-regulation of tridecane biosynthesis|up-regulation of tridecane biosynthetic process|activation of tridecane biosynthesis|activation of tridecane biosynthetic process|up-regulation of tridecane formation|upregulation of tridecane anabolism|upregulation of tridecane synthesis|positive regulation of tridecane biosynthesis|upregulation of tridecane formation|up regulation of tridecane biosynthesis|up regulation of tridecane biosynthetic process|up regulation of tridecane anabolism Any process that activates or increases the frequency, rate or extent of tridecane biosynthetic process. GO:1900885 negative regulation of tridecane biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900885 downregulation of tridecane synthesis|downregulation of tridecane biosynthetic process|downregulation of tridecane biosynthesis|downregulation of tridecane formation|down regulation of tridecane biosynthesis|down regulation of tridecane biosynthetic process|negative regulation of tridecane anabolism|down-regulation of tridecane anabolism|inhibition of tridecane biosynthetic process|inhibition of tridecane biosynthesis|negative regulation of tridecane synthesis|down-regulation of tridecane synthesis|negative regulation of tridecane formation|down-regulation of tridecane formation|inhibition of tridecane anabolism|inhibition of tridecane synthesis|inhibition of tridecane formation|down-regulation of tridecane biosynthetic process|down-regulation of tridecane biosynthesis|negative regulation of tridecane biosynthesis|down regulation of tridecane anabolism|downregulation of tridecane anabolism|down regulation of tridecane synthesis|down regulation of tridecane formation Any process that stops, prevents or reduces the frequency, rate or extent of tridecane biosynthetic process. GO:1900880 18-methylnonadec-1-ene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900880 18-methylnonadec-1-ene metabolism The chemical reactions and pathways involving 18-methylnonadec-1-ene. GO:1900882 17-methylnonadec-1-ene metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900882 17-methylnonadec-1-ene metabolism The chemical reactions and pathways involving 17-methylnonadec-1-ene. GO:1900881 18-methylnonadec-1-ene biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900881 18-methylnonadec-1-ene anabolism|18-methylnonadec-1-ene biosynthesis|18-methylnonadec-1-ene synthesis|18-methylnonadec-1-ene formation The chemical reactions and pathways resulting in the formation of 18-methylnonadec-1-ene. CHEBI:35663 carane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35663 CHEBI:35662 terpenoid fundamental parent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35662 CHEBI:35664 EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35664 CHEBI:35666 thiopurine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35666 UBERON:2000228 lateral line primordium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_2000228 lateral line primordia|llp GO:0071759 IgX immunoglobulin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071759 A protein complex composed of two identical immunoglobulin heavy chains of the IgX isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgX immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. GO:0071758 IgW immunoglobulin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071758 A protein complex composed of two identical immunoglobulin heavy chains of the IgW isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgW immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. GO:0071757 hexameric IgM immunoglobulin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071757 hexameric IgM antibody A circulating form of IgM consisting of a hexamer of IgM core units with a single J chain polypeptide. GO:0071756 pentameric IgM immunoglobulin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071756 pentameric IgM antibody A circulating form of IgM consisting of a pentamer of IgM core units with a single J chain polypeptide. GO:0071755 IgM B cell receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071755 membrane-bound IgM|surface IgM An IgM immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins. GO:0071754 IgM immunoglobulin complex, circulating biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071754 IgM antibody A polymer of five or six IgM core units each composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds; the individual IgM core units are held together via disulfide bonds with a single J chain polypeptide acting as a bridge between two of the polymeric units. Circulating IgM is present in the extracellular space, in mucosal areas or other tissues, or in the blood or lymph. GO:0071753 IgM immunoglobulin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071753 A protein complex composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and in its circulating form complexed with J chain in polymeric forms. An IgM immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. GO:0071752 secretory dimeric IgA immunoglobulin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071752 secretory dimeric IgA1 antibody|secretory dimeric IgA antibody A dimeric form of secretory IgA immunoglobulin complex. GO:0071751 secretory IgA immunoglobulin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071751 secretory IgA antibody|sIgA antibody|sIgA1 antibody A polymeric IgA immunoglobulin complex that is complexed with one chain of secretory component (SC). Polymeric IgA is present in mucosal areas, having been transported via a transcytosis mechanism in mucosal epithelial cells relying on the polymeric Ig receptor, a portion of which then remains bound to the polymeric IgA as secretory component. CHEBI:35661 car-3-ene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35661 GO:0071750 dimeric IgA immunoglobulin complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071750 dimeric IgA antibody|dimeric IgA1 antibody A protein complex composed of two monomeric IgA immunoglobulin complexes linked through both direct disulfide bonds and through a disulfide binded monomer of J chain acting as a bridge. Each IgA monomer consists of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds. Dimeric IgA is sometimes complexed additionally with secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. CHEBI:35660 HIV protease inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35660 GO:0071781 endoplasmic reticulum cisternal network biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071781 ER cisternal network A subcompartment of the endoplasmic reticulum consisting of flattened, disc-shaped domains known as cisternae. These are typically found close to the nucleus and are generally more prominent in secretory cells. GO:0071780 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0071780 GO:1900899 regulation of heptadecane metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900899 regulation of heptadecane metabolism Any process that modulates the frequency, rate or extent of heptadecane metabolic process. GO:1900898 positive regulation of heptadecane biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900898 positive regulation of heptadecane anabolism|up regulation of heptadecane biosynthetic process|activation of heptadecane formation|up regulation of heptadecane synthesis|positive regulation of heptadecane biosynthesis|positive regulation of heptadecane synthesis|up regulation of heptadecane formation|up regulation of heptadecane biosynthesis|positive regulation of heptadecane formation|upregulation of heptadecane biosynthetic process|up-regulation of heptadecane anabolism|up-regulation of heptadecane synthesis|upregulation of heptadecane biosynthesis|up-regulation of heptadecane formation|up-regulation of heptadecane biosynthetic process|upregulation of heptadecane anabolism|activation of heptadecane biosynthetic process|activation of heptadecane biosynthesis|upregulation of heptadecane synthesis|up-regulation of heptadecane biosynthesis|upregulation of heptadecane formation|activation of heptadecane anabolism|up regulation of heptadecane anabolism|activation of heptadecane synthesis Any process that activates or increases the frequency, rate or extent of heptadecane biosynthetic process. GO:1900895 positive regulation of tridecane metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900895 activation of tridecane metabolism|up regulation of tridecane metabolic process|activation of tridecane metabolic process|up-regulation of tridecane metabolism|up-regulation of tridecane metabolic process|positive regulation of tridecane metabolism|up regulation of tridecane metabolism|upregulation of tridecane metabolic process|upregulation of tridecane metabolism Any process that activates or increases the frequency, rate or extent of tridecane metabolic process. GO:1900894 negative regulation of tridecane metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900894 down-regulation of tridecane metabolic process|negative regulation of tridecane metabolism|down-regulation of tridecane metabolism|inhibition of tridecane metabolic process|downregulation of tridecane metabolism|inhibition of tridecane metabolism|down regulation of tridecane metabolism|down regulation of tridecane metabolic process|downregulation of tridecane metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of tridecane metabolic process. GO:1900897 negative regulation of heptadecane biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900897 negative regulation of heptadecane biosynthesis|down-regulation of heptadecane biosynthesis|downregulation of heptadecane formation|downregulation of heptadecane biosynthetic process|down-regulation of heptadecane anabolism|negative regulation of heptadecane anabolism|inhibition of heptadecane anabolism|down regulation of heptadecane biosynthetic process|down-regulation of heptadecane synthesis|negative regulation of heptadecane synthesis|downregulation of heptadecane biosynthesis|inhibition of heptadecane synthesis|inhibition of heptadecane biosynthetic process|inhibition of heptadecane biosynthesis|down-regulation of heptadecane formation|negative regulation of heptadecane formation|down regulation of heptadecane biosynthesis|inhibition of heptadecane formation|down regulation of heptadecane anabolism|downregulation of heptadecane anabolism|down regulation of heptadecane synthesis|down-regulation of heptadecane biosynthetic process|down regulation of heptadecane formation|downregulation of heptadecane synthesis Any process that stops, prevents or reduces the frequency, rate or extent of heptadecane biosynthetic process. GO:1900896 regulation of heptadecane biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900896 regulation of heptadecane biosynthesis|regulation of heptadecane anabolism|regulation of heptadecane synthesis|regulation of heptadecane formation Any process that modulates the frequency, rate or extent of heptadecane biosynthetic process. GO:1900891 negative regulation of pentadecane metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900891 downregulation of pentadecane metabolic process|negative regulation of pentadecane metabolism|down-regulation of pentadecane metabolism|down-regulation of pentadecane metabolic process|downregulation of pentadecane metabolism|inhibition of pentadecane metabolism|inhibition of pentadecane metabolic process|down regulation of pentadecane metabolism|down regulation of pentadecane metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of pentadecane metabolic process. GO:1900890 regulation of pentadecane metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900890 regulation of pentadecane metabolism Any process that modulates the frequency, rate or extent of pentadecane metabolic process. GO:1900893 regulation of tridecane metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900893 regulation of tridecane metabolism Any process that modulates the frequency, rate or extent of tridecane metabolic process. GO:1900892 positive regulation of pentadecane metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900892 up-regulation of pentadecane metabolism|up regulation of pentadecane metabolic process|activation of pentadecane metabolic process|positive regulation of pentadecane metabolism|up regulation of pentadecane metabolism|up-regulation of pentadecane metabolic process|upregulation of pentadecane metabolism|activation of pentadecane metabolism|upregulation of pentadecane metabolic process Any process that activates or increases the frequency, rate or extent of pentadecane metabolic process. GO:0071789 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0071789 GO:0071788 endoplasmic reticulum tubular network maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071788 ER tubular network maintenance The organization process that preserves the endoplasmic reticulum (ER) tubular network in a stable functional or structural state. The ER tubular network is the ER part that comprises the membranes with high curvature in cross-section. GO:0071787 endoplasmic reticulum tubular network formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071787 ER tubular network formation|endoplasmic reticulum tubular network assembly|ER tubular network assembly The aggregation, arrangement and bonding together of a set of components to form the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that comprises the membranes with high curvature in cross-section. GO:0071786 endoplasmic reticulum tubular network organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071786 ER tubular network organisation|endoplasmic reticulum tubular network organisation|ER tubular network organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that that has membranes with high curvature in cross-section. GO:0071785 endoplasmic reticulum cisternal network maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071785 ER cisternal network maintenance The organization process that preserves the endoplasmic reticulum (ER) cisternal network in a stable functional or structural state. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section. GO:0071784 endoplasmic reticulum cisternal network assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071784 endoplasmic reticulum cisternal network formation|ER cisternal network formation|ER cisternal network assembly The aggregation, arrangement and bonding together of a set of components to form the endoplasmic reticulum (ER) cisternal network. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section. GO:0071783 endoplasmic reticulum cisternal network organization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071783 ER cisternal network organisation|endoplasmic reticulum cisternal network organisation|ER cisternal network organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) cisternal network. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section. GO:0071782 endoplasmic reticulum tubular network biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071782 ER tubular network A subcompartment of the endoplasmic reticulum consisting of tubules having membranes with high curvature in cross-section. GO:0071770 DIM/DIP cell wall layer assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071770 DIM cell wall layer assembly|DIM/DIP cell wall layer biogenesis|PDIM cell wall layer assembly The aggregation, arrangement and bonding together of a set of components, including (phenyl)phthiocerol, phthiodiolone, phthiotriol dimycocerosate and diphthioceranate, to form the DIM/DIP layer of the Actinobacterium-type cell wall. CHEBI:21006 D-glucose monophosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21006 CHEBI:21005 D-glucose bisphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21005 CHEBI:35649 morphinan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35649 UBERON:0016612 auditory hillocks, pharyngeal arch 2 derived biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016612 A collection of protruberances derived from pharyngeal arch 2 that develop into the concha, antihelix and antitragus. UBERON:0016611 auditory hillocks, pharyngeal arch 1 derived biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0016611 A collection of protruberances derived from pharyngeal arch 1 that develop into the tragus, crus of the helix, and helix. GO:0140195 positive regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140195 Any process that activates or increases the frequency, rate or extent of an adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in some heart process. CHEBI:35640 adrenergic uptake inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35640 GO:0140194 negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140194 Any process that stops, prevents or reduces the frequency, rate or extent of an adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in some heart process. CHEBI:35643 aporphine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35643 GO:0140196 positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140196 Any process that activates or increases the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor signaling pathway involved in some heart process. GO:0140199 negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140199 Any process that stops, prevents or reduces the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor signaling pathway involved in some heart process. GO:0071779 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0071779 GO:0071778 obsolete WINAC complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071778 WINAC complex OBSOLETE. A SWI/SNF-type complex that directly interacts with the vitamin D receptor (VDR) through the Williams syndrome transcription factor (WSTF), and mediates the recruitment of unliganded VDR to VDR target sites in promoters. The WINAC complex contains at least 13 subunits, including WSTF, several SWI/SNF components, and DNA replication-related factors. CHEBI:21008 glucose phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_21008 GO:0071777 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0071777 GO:0071776 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0071776 GO:0071775 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0071775 GO:0071774 response to fibroblast growth factor biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071774 response to fibroblast growth factor stimulus|response to FGF stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fibroblast growth factor stimulus. GO:0071773 cellular response to BMP stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071773 cellular response to bone morphogenetic protein stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bone morphogenetic protein (BMP) stimulus. GO:0140193 regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140193 Any process that modulates the frequency, rate or extent of an adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in some heart process. GO:0071772 response to BMP biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071772 response to BMP stimulus|response to bone morphogenetic protein stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bone morphogenetic protein (BMP) stimulus. GO:0071771 aldehyde decarbonylase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071771 decarbonylase activity Catalysis of the reaction: a C(n) aldehyde = C(n-1) alkane + CO. CHEBI:3892 corticotropin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_3892 GO:0140192 regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140192 Any process that modulates the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor signaling pathway involved in some heart process. CHEBI:35616 trans-anethole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35616 GO:0140147 zinc ion export from vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140147 The directed movement of zinc ions from inside the vacuole across the vacuolar membrane and into the cytosol. CHEBI:35615 tropane biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35615 CHEBI:35618 aromatic ether biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35618 CHEBI:35617 flavouring agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35617 CHEBI:35619 L-alpha-aminobutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35619 OBO:GOCHE_24020 substance with fat-soluble vitamin role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_24020 GO:0140140 mitochondrial guanine nucleotide transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140140 The process in which a guanine nucleotide is transported across a mitochondrial membrane, into or out of the mitochondrion. CHEBI:11641 2-oxopent-4-enoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_11641 UBERON:0002040 bronchial artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002040 rami bronchiales partis thoracicae aortae|bronchial arterial tree|arteriae bronchiales A systemic artery that supplies the lung with with oxygenated blood. UBERON:0002043 dorsal raphe nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002043 DR|nucleus dorsalis raphes|nucleus raphes posterior|nucleus raphes dorsalis|nucleus raphes posterior|dorsal nucleus of the raphe|dorsal raphe|DRN|dorsal raphé|cell group b7|posterior raphe nucleus|inferior raphe nucleus|posterior raphe nucleus|nucleus raphe dorsalis|nucleus raphe posterior|dorsal nucleus raphe A large raphe nucleus extending from the anterior part of the pons through the mesencephalon; its neurons are serotoninergic[NIF]. The dorsal raphe nucleus is a part of the raphe nucleus and consists of rostral and caudal subdivisions. The rostral aspect of the dorsal raphe is further divided into interfascicular, ventral, ventrolateral and dorsal subnuclei. The projections of the dorsal raphe have been found to vary topographically, and thus the subnuclei differ in their projections. An increased number of cells in the lateral aspects of the dorsal raphe is characteristic of humans and other primates. [WP,unvetted]. GO:0140142 nucleocytoplasmic carrier activity biolink:MolecularActivity go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0140142 miRNA transporter activity|nucleocytoplasmic importin/exportin activity|pre-miRNA transporter activity Carries substances between the nucleus and the cytoplasm of a cell by moving along with the target protein. CHEBI:35610 antineoplastic agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35610 UBERON:0002042 lymphatic vessel endothelium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002042 endothelium of lymph vessel|lymphatic endothelium|lymph vessel endothelium|endothelium of lymphatic vessel|lymphatic vessel endothelium An endothelium that is part of a lymphatic vessel [Automatically generated definition]. GO:0140141 mitochondrial potassium ion transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140141 The process in which a potassium ion is transported across a mitochondrial membrane, into or out of the mitochondrion. GO:0140146 calcium ion import into vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140146 The directed movement of calcium cations into the vacuole across the vacuolar membrane. GO:0140145 copper ion export from vacuole biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140145 The directed movement of copper ions out of the vacuole across the vacuolar membrane. UBERON:0002049 vasculature biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002049 vascular network An interconnected tubular multi-tissue structure contains fluid that is actively transported around the organism[ZFA]. Examples: vasculature of lung, vasculature of face. OBO:GOCHE_24028 substance with iron(3+) chelator role biolink:OntologyClass go-plus 1_STAR http://purl.obolibrary.org/obo/GOCHE_24028 UBERON:0002048 lung biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002048 pulmo Respiration organ that develops as an outpocketing of the esophagus. UBERON:0002047 pontine raphe nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002047 raphe pontis nucleus|raphe (mediana pontina)|nucleus raphe pontis|raphe pontis|raphe of pons|nucleus raphes pontis The pontine raphe nucleus is one of the raphe nuclei. It is located in the pontine tegmentum. [WP,unvetted]. UBERON:0002046 thyroid gland biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002046 thyroid|glandula thyroidea A two-lobed endocrine gland found in all vertebrates, located in front of and on either side of the trachea in humans, and producing various hormones, such as triiodothyronine and calcitonin[BTO]. GO:0071792 bacillithiol metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071792 bacillithiol metabolism The chemical reactions and pathways involving bacillithiol, the alpha-anomeric glycoside of L-cysteinyl-D-glucosamine with L-malic acid. Bacillithiol, produced widely in the Firmicutes and sporadically in other bacterial lineages, is a low-molecular-weight thiol analogous to mycothiol in the Actinomycetes and glutathione in many species. GO:0071791 chemokine (C-C motif) ligand 5 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071791 RANTES binding|Regulated upon Activation, Normal T-cell Expressed, and Secreted binding|CCL5 binding Interacting selectively and non-covalently with chemokine (C-C motif) ligand 5. GO:0071790 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0071790 CHEBI:35627 beta-lactam biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35627 UBERON:0002030 nipple biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002030 papillary part of breast|papilla of breast|thele|teat|thelium|papilla mammaria|papilla mammae Projection of skin containing the outlets for 15-20 lactiferous ducts arranged cylindrically around the tip. GO:0140131 positive regulation of lymphocyte chemotaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140131 Any process that activates or increases the frequency, rate or extent of lymphocyte chemotaxis. CHEBI:35621 alpha-aminobutyric acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35621 UBERON:0002031 epithelium of bronchus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002031 bronchial trunk epithelium|bronchi epithelium|bronchial epithelium|epithelial tissue of bronchus|epithelium of bronchi|epithelium of bronchial trunk|epithelial tissue of bronchi|epithelial tissue of bronchial trunk|bronchi epithelial tissue|bronchial trunk epithelial tissue|bronchus epithelial tissue|bronchus epithelium An epithelium that is part of a bronchus [Automatically generated definition]. CHEBI:35620 vasodilator agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35620 GO:0140133 suppression by symbiont of host cytokine production biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140133 negative regulation by symbiont of host cytokine production|suppression by symbiont of host cytokine secretion Any process in which a symbiont stops, prevents, or reduces the rate or extent of cytokine production by the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. CHEBI:35623 anticonvulsant biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35623 GO:0140132 iron-sulfur cluster carrier activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140132 Binding to an iron-sulfur cluster and delivering it to an acceptor molecule. CHEBI:35622 thiazolidines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35622 GO:0140135 mechanosensitive cation channel activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140135 mechanically-gated cation channel activity Enables the transmembrane transfer of a cation by a channel that opens in response to a mechanical stress. CHEBI:35625 EC 3.5.2.6 (beta-lactamase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35625 CHEBI:35624 azaspiro compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35624 UBERON:0002038 substantia nigra biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002038 nucleus pigmentosus subthalamo-peduncularis|SN|Soemmering's substance|substancia nigra|substantia nigra (Soemmerringi)|nucleus of basis pedunculi Predominantly gray matter midbrain structure lying dorsal to the crus cerebri and ventral to the midbrain tegmentum. It is divided into a dorsal, cellularly compact region known as the pars compacta and a more ventrally located, containing more loosely packed cells, the pars reticulata. The most lateral region of the reticulata is identified as the pars lateralis (MM). UBERON:0002037 cerebellum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002037 corpus cerebelli|parencephalon|infratentorial region|epencephalon-1 Part of the metencephalon that lies in the posterior cranial fossa behind the brain stem. It is concerned with the coordination of movement[MESH]. A large dorsally projecting part of the brain concerned especially with the coordination of muscles and the maintenance of bodily equilibrium, situated between the brain stem and the back of the cerebrum , and formed in humans of two lateral lobes and a median lobe[BTO]. Brain structure derived from the anterior hindbrain, and perhaps including posterior midbrain. The cerebellum plays a role in somatic motor function, the control of muscle tone, and balance[ZFA]. GO:0071799 cellular response to prostaglandin D stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071799 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin D stimulus. GO:0071798 response to prostaglandin D biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071798 response to prostaglandin D stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin D stimulus. GO:0071797 LUBAC complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071797 A ubiquitin ligase complex that catalyzes linear head-to-tail polyubiquitin conjugation on its targets. In human the complex consists of RBCK1, RNF31 and SHARPIN, and has an MW of approximately 600 kDa, suggesting a heteromultimeric assembly of its subunits. LUBAC stands for Linear Ubiquitin Chain Assembly Complex. GO:0071796 K6-linked polyubiquitin modification-dependent protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071796 Interacting selectively and non-covalently with a protein upon poly-ubiquitination formed by linkages between lysine residues at position 6 in the target protein. GO:0071795 K11-linked polyubiquitin modification-dependent protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071795 Interacting selectively and non-covalently with a protein upon poly-ubiquitination formed by linkages between lysine residues at position 11 in the target protein. UBERON:0002033 arrector muscle of hair biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002033 pilomotor muscle|arrector pili muscle|arrector pilli muscle|arrector pilli|erector pili|arrector pilorum|erectores pilorum|arrector pili smooth muscle|arectores pilorum|arrector pili|arrector pilorum muscle of hair A tiny smooth muscle that connects the hair follicle with the dermis. GO:0071794 CAP-Gly domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071794 Interacting selectively and non-covalently with a CAP-Gly domain of a protein. The CAP_Gly domain is a conserved, glycine-rich domain of about 42 residues found in some cytoskeleton-associated proteins, and features a novel protein fold containing three beta-sheets. UBERON:0002036 striated muscle tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002036 striated muscle Muscle tissue that contains fibers that are divided by transverse bands into striations. GO:0071793 bacillithiol biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071793 bacillithiol anabolism|bacillithiol synthesis|bacillithiol formation|bacillithiol biosynthesis The chemical reactions and pathways resulting in the formation of bacillithiol, the alpha-anomeric glycoside of L-cysteinyl-D-glucosamine with L-malic acid. Bacillithiol, produced widely in the Firmicutes and sporadically in other bacterial lineages, is a low-molecular-weight thiol analogous to mycothiol in the Actinomycetes and glutathione in many species. UBERON:0002019 accessory XI nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002019 nervus accessorius [XI]|eleventh cranial nerve|accessory nerve [XI]|Willis' nerve|spinal accessory nerve tree|pars spinalis nervus accessorius|cranial nerve XI|CN-XI|spinal part of accessory nerve|accessory XI nerve|spinal accessory nerve|cervical accessory nerve|radix spinalis nervus accessorius|accessory spinal nerve|accessory XI|accessory nerve A cranial nerve that originates from neurons in the medulla and in the cervical spinal cord. GO:0140161 monocarboxylate:sodium symporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140161 Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monocarboxylate(out) + Na+(out) = monocarboxylate(in) + Na+(in). GO:0140164 Golgi transport complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140164 COG complex binding Interacting selectively and non-covalently with the Golgi transport complex, a multisubunit tethering complex of the CATCHR family. UBERON:0002020 gray matter biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002020 grey matter|neuronal grey matter|grey matter of neuraxis|gray matter|gray matter of neuraxis|substantia grisea|grey substance|grisea|gray mater A nervous system structure composed primarily of nerve cell bodies (somas). May also include dendrites and the initial unmyelinated portion of axons. UBERON:0002029 epithelium of gall bladder biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002029 gall bladder epithelial tissue|biliary epithelium|gallbladder epithelium|epithelium of gallbladder|epithelial tissue of gallbladder|gallbladder epithelial tissue|epithelial tissue of gall bladder|gall bladder epithelium The simple columnar epithelial lining of the gall bladder. UBERON:0002028 hindbrain biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002028 rhombencephalon The most posterior of the three principal regions of the brain. In mammals and birds the hindbrain is divided into a rostral metencephalon and a caudal myelencephalon. In zebrafish, with the exception of the cerebellum, the ventral remainder of the metencephalon can be separated only arbitrarily from the more caudal myelencephalic portion of the medulla oblongata (From: Neuroanatomy of the Zebrafish Brain)[ZFA]. Organ component of neuraxis that has as its parts the pons, cerebellum and medulla oblongata[FMA]. GO:0140160 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0140160 UBERON:0002008 cardiac nerve plexus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002008 autonomic plexus of heart|plexus cardiacus|heart autonomic nerve plexus|cardiac plexus|autonomic nerve plexus of heart|heart autonomic plexus A plexus of nerves situated at the base of the heart that innervate the heart. GO:0140159 borate export across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140159 The directed movement of borate from inside of a cell, across the plasma membrane and into the extracellular region. CHEBI:35605 carbon oxoacid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35605 CHEBI:35604 carbon oxoanion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35604 CHEBI:35608 EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35608 CHEBI:35601 2H-chromene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35601 CHEBI:11656 2-succinyl-6-hydroxycyclohexa-2,4-diene-1-carboxylic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_11656 CHEBI:35603 4H-chromene biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35603 GO:0140157 ammonium import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140157 The directed movement of an ammonium ion from outside of a cell, across the plasma membrane and into the cytosol. CHEBI:35602 chromene biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35602 UBERON:0002016 pulmonary vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002016 venae pulmonales|pulmonary venous tree organ part Pulmonary veins are blood vessels that transport blood from the lungs to the heart[GO]. UBERON:0002015 kidney capsule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002015 capsula fibrosa renis|renal capsule|capsule of kidney|fibrous capsule of kidney the tough fibrous layer surrounding the kidney which is covered in a thick layer of perirenal adipose tissue that functions to provide some protection from trauma and damage UBERON:0002017 portal vein biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002017 portal venous tree organ part A vein that conducts blood from the digestive organs, spleen, pancreas, and gallbladder to the liver[BTO]. UBERON:0002012 pulmonary artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002012 arteria pulmonalis|truncus pulmonalis|pulmonary arterial tree organ part|pulmonary arterial tree|pulmonary arterial subtree An artery that carries deoxygenated blood from heart to the lungs. They are the only arteries (other than umbilical arteries in the fetus) that carry deoxygenated blood.. UBERON:0002011 thoracodorsal artery biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002011 arteria thoracodorsalis The thoracodorsal artery is a branch of the subscapular artery. It travels inferiorly with the thoracodorsal nerve and supplies the latissimus dorsi. [WP,unvetted]. GO:0032319 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032319 GO:0032318 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032318 GO:0032317 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032317 GO:0032316 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032316 GO:0032315 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032315 GO:0007359 posterior abdomen determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007359 The regionalization process in which the posterior (abdominal) regions of the embryo are specified by the gap genes. GO:0007358 establishment of central gap gene boundaries biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007358 Specification of the borders of central gap gene expression mediated largely by the effects of other gap genes; in insects this is exemplified by knirps repression of Kruppel. GO:0032314 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032314 GO:0046965 retinoid X receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046965 RXR binding Interacting selectively and non-covalently with a retinoid X receptor. GO:0007357 obsolete positive regulation of central gap gene transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007357 up regulation of central gap gene transcription|upregulation of central gap gene transcription|stimulation of central gap gene transcription|activation of central gap gene transcription|up-regulation of central gap gene transcription|activation of central gap gene OBSOLETE. The activation of genes encoding transcription factors in the central region of an insect embryo by a combination of maternal regulatory signals and interactions among themselves; exemplified by the activation of expression of the Drosophila Kruppel gene by the hunchback and bicoid gene products. OBO:GOCHE_38867 substance with anaesthetic role biolink:OntologyClass go-plus 3_STAR http://purl.obolibrary.org/obo/GOCHE_38867 CHEBI:142853 (2R)-glufosinate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_142853 GO:0007356 thorax and anterior abdomen determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007356 Specification of the central (trunk) regions of the embryo by the gap genes; exemplified in insects by the actions of the Kruppel gene product. GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046964 Reactome:R-HSA-741449 3'-phosphoadenosine 5'-phosphosulphate transporter activity|adenosine 3'-phosphate 5'-phosphosulfate transmembrane transporter activity|PAPS transporter activity Enables the transfer of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride synthesized from adenosine 5'-phosphosulfate, from one side of a membrane to the other. CHEBI:142852 glufosinate-P biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_142852 CHEBI:84548 2-demethylmenaquinol-11 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84548 GO:0046963 3'-phosphoadenosine 5'-phosphosulfate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046963 PAPS transport|adenosine 3'-phosphate 5'-phosphosulfate transport|3'-phosphoadenosine 5'-phosphosulphate transport The directed movement of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride synthesized from adenosine 5'-phosphosulfate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0007355 anterior region determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007355 Specification of the anterior (head and thoracic segments) of the embryo by the gap genes; exemplified in insects by the actions of hunchback gene product. CHEBI:142851 2-amino-4-[hydroxy(methyl)phosphoryl]butanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_142851 GO:0046962 sodium-transporting ATPase activity, rotational mechanism biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046962 MetaCyc:3.6.3.15-RXN|RHEA:58157|EC:7.2.2.1 vacuolar-type Na+-translocating ATPase|sodium-translocating F-type ATPase activity|sodium-transporting two-sector ATPase activity|Na+-translocating F1Fo-ATPase|ATP phosphohydrolase (Na+-transporting) activity|vacuolar-type Na+-ATPase|Na(+)-transporting two-sector ATPase activity|ATP synthase, sodium ion specific activity|sodium transporting ATPase activity, rotational mechanism|Na+-transporting two-sector ATPase|sodium-translocating V-type ATPase activity|Na(+)-translocating ATPase activity|Na+-translocating ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) => ADP + phosphate + Na+(out), by a rotational mechanism. CHEBI:84547 menaquinol-11 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84547 GO:0007354 zygotic determination of anterior/posterior axis, embryo biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007354 The specification of the anterior/posterior axis of the embryo by products of genes expressed in the zygote; exemplified in insects by the gap genes, pair rule genes and segment polarity gene cascade. GO:0046961 proton-transporting ATPase activity, rotational mechanism biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046961 MetaCyc:ATPSYN-RXN|RHEA:57721|EC:7.1.2.2 FoF1-ATPase|hydrogen ion translocating F-type ATPase activity|hydrogen ion transporting ATPase activity, rotational mechanism|F0F1-ATPase|F1-ATPase|F(1)-ATPase activity|mitochondrial ATPase activity|hydrogen ion transporting two-sector ATPase activity|F(o)F(1)-ATPase activity|F(0)F(1)-ATPase activity|hydrogen ion translocating V-type ATPase activity|H(+)-transporting ATP synthase activity|H+-transporting ATPase activity|chloroplast ATPase activity|ATP phosphohydrolase (H+-transporting) activity|ATP synthase activity|hydrogen ion translocating A-type ATPase activity Enables the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism. CHEBI:84546 2-demethylmenaquinol-10 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84546 GO:0007353 obsolete ventral/lateral system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007353 ventral/lateral system OBSOLETE. (Was not defined before being made obsolete). GO:0046960 sensitization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046960 Wikipedia:Sensitization An increased in a behavioral response to a repeated stimulus. For example, a shock to the tail of the marine snail Aplysia, to which the snail responds by withdrawing its gill, will result in increased gill withdrawal the next time the skin is touched. GO:0007352 zygotic specification of dorsal/ventral axis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007352 zygotic determination of dorsal-ventral axis|zygotic determination of dorsal/ventral axis|zygotic determination of dorsoventral axis The specification of the dorsal/ventral axis of the embryo, through the products of genes expressed in the zygote. CHEBI:60584 bicozamycin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60584 CHEBI:84544 menaquinol-10 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84544 GO:0007351 tripartite regional subdivision biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007351 Subdivision of the embryo along the anterior/posterior axis into anterior, posterior and terminal regions. GO:0071919 G-quadruplex DNA formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071919 G quartet DNA formation|G quadruplex DNA formation|G-quartet DNA formation A DNA metabolic process that results in the formation of G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad or G-quartet. The stacking of several layers of G-quartets forms G-quadruplexes, in which one or more DNA single strands are assembled in parallel and/or antiparallel, with interactions that can be either intra- or intermolecular in nature. GO:0007350 blastoderm segmentation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007350 The hierarchical steps resulting in the progressive subdivision of the anterior/posterior axis of the embryo. CHEBI:84543 1-oleoyl-2-linoleyl-sn-glycero-3-phosphoethanolamine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84543 GO:0071929 alpha-tubulin acetylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071929 The addition of an acetyl group to the lysine 40 residue of alpha-tubulin. GO:0007360 obsolete positive regulation of posterior gap gene transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007360 upregulation of posterior gap gene transcription|stimulation of posterior gap gene transcription|up-regulation of posterior gap gene transcription|activation of posterior gap gene transcription|activation of posterior gap gene|knirps activation|up regulation of posterior gap gene transcription OBSOLETE. The activation of genes encoding transcription factors in the posterior region of an insect embryo by a combination of maternal regulatory signals and interactions among themselves; exemplified by the activation of expression of the Drosophila knirps gene. CHEBI:84542 2-demethylmenaquinol-9 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84542 CHEBI:166828 Saccharolipids biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_166828 GO:0071928 tyramine signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071928 tyramine signalling pathway The series of molecular signals generated as a consequence of tyramine binding to a cell surface receptor. CHEBI:84541 menaquinol-9 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84541 CHEBI:60585 3,6-diamino-10-methylacridinium biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60585 CHEBI:84540 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84540 CHEBI:142859 glufosinate-P zwitterion(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142859 GO:0071927 octopamine signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071927 octopamine signalling pathway The series of molecular signals generated as a consequence of octopamine binding to a cell surface receptor. GO:0071926 endocannabinoid signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071926 endocannabinoid signalling pathway The series of molecular signals generated as a consequence of an endocannabinoid binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription. Endocannabinoids are small molecules derived from arachidonic acid, anandamide (arachidonoylethanolamide) and 2-arachidonoylglycerol. CHEBI:142858 (2R)-glufosinate zwitterion(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142858 CHEBI:166829 ochratoxin A(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_166829 GO:0046969 NAD-dependent histone deacetylase activity (H3-K9 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046969 Reactome:R-HSA-9604829 Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 9) + H2O = histone H3 L-lysine (position 9) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 9 of the histone H3 protein. GO:0071925 thymic stromal lymphopoietin production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0071925 TSLP production The appearance of thymic stromal lymphopoietin (TSLP) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0071924 chemokine (C-C motif) ligand 22 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0071924 CCL22 production|CCL-22 production|C-C motif chemokine 22 production The appearance of chemokine (C-C motif) ligand 22 (CCL22) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. CHEBI:142856 glufosinate-P zwitterion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_142856 GO:0046968 peptide antigen transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046968 The directed movement of a peptide antigen into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein. GO:0071923 negative regulation of cohesin loading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071923 negative regulation of cohesin localisation to chromatin|negative regulation of cohesin localization to chromatin|negative regulation of cohesin association with chromatin Any process that stops, prevents, or reduces the frequency, rate or extent of a process in which a cohesin complex is transported to, or maintained at, a part of a chromosome that is organized into chromatin. GO:0046967 cytosol to endoplasmic reticulum transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046967 cytosol to ER transport|cytosol to endoplasmic reticulum transport The directed movement of substances from the cytosol to the endoplasmic reticulum of a cell. GO:0071922 regulation of cohesin loading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071922 regulation of cohesin association with chromatin|regulation of cohesin localisation to chromatin|regulation of cohesin localization to chromatin Any process that modulates the frequency, rate or extent of a process in which a cohesin complex is transported to, or maintained at, a part of a chromosome that is organized into chromatin. GO:0046966 thyroid hormone receptor binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046966 ligand-dependent thyroid hormone receptor interactor activity Interacting selectively and non-covalently with a thyroid hormone receptor. CHEBI:142854 (2R)-glufosinate zwitterion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_142854 GO:0071921 cohesin loading biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071921 cohesin localisation to chromatin|cohesin localization to chromatin|cohesin association with chromatin The protein localization to chromatin by which a cohesin ring complex is topologically linked to DNA. GO:0032313 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032313 GO:0071920 cleavage body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071920 A nuclear body that contains proteins involved in pre-mRNA 3'-end cleavage and polyadenylation, such as DDX1, CSTF2 and CPSFs, as well as the transcription factors TFIIE and TFIIF. Cleavage bodies are localized adjacent to Cajal bodies and are involved in mRNA3'-end processing. GO:0032312 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032312 GO:0032311 angiogenin-PRI complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032311 angiogenin-placental ribonuclease inhibitor complex A stable heterodimer of angiogenin and placental ribonuclease inhibitor; interaction between angiogenin and PRI prevents angiogenin binding to its receptor to stimulate angiogenesis. GO:0032310 prostaglandin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032310 prostacyclin secretion The regulated release of a prostaglandin, any of a group of biologically active metabolites which contain a cyclopentane ring, from a cell or a tissue. GO:1900804 brevianamide F catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900804 cyclo-L-Trp-L-Pro breakdown|L-prolyl-L-tryptophan anhydride degradation|tryptophan-proline diketopiperazine catabolic process|cyclo-L-Trp-L-Pro catabolic process|L-prolyl-L-tryptophan anhydride breakdown|L-tryptophyl-L-proline cyclic anhydride degradation|cyclo-(Trp-Pro) catabolism|L-prolyl-L-tryptophan anhydride catabolic process|L-tryptophyl-L-proline cyclic anhydride breakdown|cyclo-(Trp-Pro) degradation|L-tryptophyl-L-proline cyclic anhydride catabolism|brevianamide F catabolism|L-tryptophyl-L-proline cyclic anhydride catabolic process|cyclo-(Trp-Pro) breakdown|L-prolyl-L-tryptophan anhydride catabolism|cyclo-L-tryptophanyl-L-proline degradation|cyclo-(Trp-Pro) catabolic process|cyclo-L-Trp-L-Pro catabolism|tryptophan-proline diketopiperazine catabolism|cyclo-L-tryptophanyl-L-proline breakdown|tryptophan-proline diketopiperazine degradation|brevianamide F degradation|cyclo-L-Trp-L-Pro degradation|cyclo-L-tryptophanyl-L-proline catabolism|cyclo-L-tryptophanyl-L-proline catabolic process|brevianamide F breakdown|tryptophan-proline diketopiperazine breakdown The chemical reactions and pathways resulting in the breakdown of brevianamide F. GO:1900803 brevianamide F metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900803 L-prolyl-L-tryptophan anhydride metabolic process|cyclo-L-tryptophanyl-L-proline metabolism|L-tryptophyl-L-proline cyclic anhydride metabolic process|cyclo-(Trp-Pro) metabolism|L-tryptophyl-L-proline cyclic anhydride metabolism|brevianamide F metabolism|cyclo-L-tryptophanyl-L-proline metabolic process|L-prolyl-L-tryptophan anhydride metabolism|tryptophan-proline diketopiperazine metabolic process|cyclo-L-Trp-L-Pro metabolic process|cyclo-L-Trp-L-Pro metabolism|tryptophan-proline diketopiperazine metabolism The chemical reactions and pathways involving brevianamide F. GO:0032309 icosanoid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032309 eicosanoid secretion The controlled release of icosanoids, any of a group of C20 polyunsaturated fatty acids from a cell or a tissue. GO:0032308 positive regulation of prostaglandin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032308 up-regulation of prostaglandin secretion|positive regulation of prostacyclin secretion|upregulation of prostaglandin secretion|up regulation of prostaglandin secretion|activation of prostaglandin secretion|stimulation of prostaglandin secretion Any process that activates or increases the frequency, rate or extent of the regulated release of a prostaglandin from a cell. GO:1900806 ergot alkaloid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900806 ergot alkaloids breakdown|ergot alkaloid catabolism|ergot alkaloids catabolic process|ergot alkaloid degradation|ergot alkaloid breakdown|ergot alkaloids catabolism|ergot alkaloids degradation The chemical reactions and pathways resulting in the breakdown of ergot alkaloid. GO:0032307 negative regulation of prostaglandin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032307 inhibition of prostaglandin secretion|negative regulation of prostacyclin secretion|down regulation of prostaglandin secretion|downregulation of prostaglandin secretion|down-regulation of prostaglandin secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a prostaglandin from a cell. GO:1900805 brevianamide F biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900805 cyclo-L-tryptophanyl-L-proline biosynthesis|cyclo-(Trp-Pro) formation|cyclo-L-tryptophanyl-L-proline biosynthetic process|cyclo-L-tryptophanyl-L-proline anabolism|cyclo-L-tryptophanyl-L-proline synthesis|tryptophan-proline diketopiperazine anabolism|brevianamide F anabolism|cyclo-L-Trp-L-Pro anabolism|cyclo-L-tryptophanyl-L-proline formation|cyclo-(Trp-Pro) biosynthesis|cyclo-(Trp-Pro) biosynthetic process|tryptophan-proline diketopiperazine synthesis|brevianamide F synthesis|cyclo-L-Trp-L-Pro synthesis|C16H17N3O2 anabolism|L-prolyl-L-tryptophan anhydride anabolism|tryptophan-proline diketopiperazine formation|brevianamide F formation|L-tryptophyl-L-proline cyclic anhydride biosynthetic process|cyclo-L-Trp-L-Pro formation|L-tryptophyl-L-proline cyclic anhydride biosynthesis|C16H17N3O2 synthesis|brevianamide F biosynthesis|L-prolyl-L-tryptophan anhydride synthesis|L-tryptophyl-L-proline cyclic anhydride anabolism|C16H17N3O2 formation|L-prolyl-L-tryptophan anhydride formation|L-prolyl-L-tryptophan anhydride biosynthesis|C16H17N3O2 biosynthetic process|C16H17N3O2 biosynthesis|L-prolyl-L-tryptophan anhydride biosynthetic process|L-tryptophyl-L-proline cyclic anhydride synthesis|cyclo-(Trp-Pro) anabolism|cyclo-L-Trp-L-Pro biosynthetic process|cyclo-L-Trp-L-Pro biosynthesis|L-tryptophyl-L-proline cyclic anhydride formation|tryptophan-proline diketopiperazine biosynthetic process|tryptophan-proline diketopiperazine biosynthesis|cyclo-(Trp-Pro) synthesis The chemical reactions and pathways resulting in the formation of brevianamide F. GO:1900800 cspyrone B1 metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900800 cspyrone B1 metabolism The chemical reactions and pathways involving cspyrone B1. GO:0032306 regulation of prostaglandin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032306 regulation of prostacyclin secretion Any process that modulates the frequency, rate or extent of the regulated release of a prostaglandin from a cell. GO:0032305 positive regulation of icosanoid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032305 up-regulation of icosanoid secretion|positive regulation of eicosanoid secretion|upregulation of icosanoid secretion|up regulation of icosanoid secretion|activation of icosanoid secretion|stimulation of icosanoid secretion Any process that activates or increases the frequency, rate or extent of the controlled release of an icosanoid from a cell. GO:0032304 negative regulation of icosanoid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032304 inhibition of icosanoid secretion|negative regulation of eicosanoid secretion|down regulation of icosanoid secretion|downregulation of icosanoid secretion|down-regulation of icosanoid secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of an icosanoid from a cell. GO:1900802 cspyrone B1 biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900802 cspyrone B1 biosynthesis|cspyrone B1 anabolism|cspyrone B1 synthesis|cspyrone B1 formation The chemical reactions and pathways resulting in the formation of cspyrone B1. GO:1900801 cspyrone B1 catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900801 cspyrone B1 catabolism|cspyrone B1 degradation|cspyrone B1 breakdown The chemical reactions and pathways resulting in the breakdown of cspyrone B1. GO:0007369 gastrulation biolink:BiologicalProcess go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0007369 Wikipedia:Gastrulation A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm. GO:0032303 regulation of icosanoid secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032303 regulation of eicosanoid secretion Any process that modulates the frequency, rate or extent of the controlled release of an icosanoid from a cell. GO:0007368 determination of left/right symmetry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007368 determination of left/right asymmetry The establishment of an organism's body plan or part of an organism with respect to the left and right halves. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry. GO:0046976 histone methyltransferase activity (H3-K27 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046976 Reactome:R-HSA-3240295 histone methylase activity (H3-K27 specific)|histone lysine N-methyltransferase activity (H3-K27 specific) Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 27) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 27). This reaction is the addition of a methyl group onto lysine at position 27 of the histone H3 protein. CHEBI:142842 andrastin A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_142842 CHEBI:166831 copper chelator biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_166831 GO:0046975 histone methyltransferase activity (H3-K36 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046975 histone methylase activity (H3-K36 specific)|histone lysine N-methyltransferase activity (H3-K36 specific) Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 36) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 36). This reaction is the addition of a methyl group onto lysine at position 36 of the histone H3 protein. GO:0007367 segment polarity determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007367 Division of the 14 parasegments of the embryo into anterior and posterior compartments; exemplified by the actions of the segment polarity gene products. GO:0046974 histone methyltransferase activity (H3-K9 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046974 Reactome:R-HSA-427527|Reactome:R-HSA-427336 histone lysine N-methyltransferase activity (H3-K9 specific)|histone methylase activity (H3-K9 specific) Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 9) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 9). This reaction is the addition of a methyl group onto lysine at position 9 of the histone H3 protein. GO:0007366 periodic partitioning by pair rule gene biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007366 Allocation of cells to parasegments in the embryo, through the action of overlapping series of pair rule gene activities. CHEBI:84559 2,4-dinitroanisole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84559 GO:0046973 obsolete histone lysine N-methyltransferase activity (H3-K24 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046973 histone lysine N-methyltransferase activity (H3-K24 specific) OBSOLETE. Catalysis of the addition of a methyl group onto lysine at position 24 of the histone H3 protein. GO:0007365 periodic partitioning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007365 The regionalization process that divides the spatial regions of an embryo into serially repeated regions. GO:0007364 establishment of terminal gap gene boundary biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007364 Specification of the borders of terminal gap gene expression mediated largely by the effects of other gap genes. GO:0046972 histone acetyltransferase activity (H4-K16 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046972 histone lysine acetyltransferase activity (H4-K16 specific) Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 16) = CoA + histone H4 N6-acetyl-L-lysine (position 16). This reaction represents the addition of an acetyl group to the lysine at position 16 of histone H4. GO:0007363 obsolete positive regulation of terminal gap gene transcription biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007363 up regulation of terminal gap gene transcription|activation of terminal gap gene transcription|activation of terminal gap gene|stimulation of terminal gap gene transcription|up-regulation of terminal gap gene transcription|upregulation of terminal gap gene transcription OBSOLETE. The activation of genes encoding transcription factors at the anterior and posterior ends of an insect embryo by a combination of maternal regulatory signals and interactions among themselves; exemplified by the activation of expression of the Drosophila tailless and huckebein genes. GO:0046971 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046971 GO:0071909 determination of stomach left/right asymmetry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071909 Determination of the asymmetric location of the stomach with respect to the left and right halves of the organism. GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific) biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046970 Catalysis of the reaction: histone H4 N6-acetyl-L-lysine (position 16) + H2O = histone H4 L-lysine (position 16) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 16 of the histone H4 protein. GO:0007362 terminal region determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007362 Specification of the terminal regions (the two non-segmented ends) of the embryo by the gap genes; exemplified in insects by the actions of huckebein and tailless gene products. GO:0071908 determination of intestine left/right asymmetry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071908 Determination of the asymmetric location of the intestine loops with respect to the left and right halves of the organism. CHEBI:84554 3,5-dihydroxyphenylacetyl-CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84554 GO:0007361 establishment of posterior gap gene boundaries biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007361 Specification of the borders of posterior gap gene expression mediated largely by the effects of other gap genes; in insects this is exemplified by hunchback and tailless repression of knirps. GO:0007371 ventral midline determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007371 determination of posterior border of ventral midline|determination of anterior border of ventral midline The regionalization process in which the area where the ventral midline will form is specified. GO:0071918 urea transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071918 urea membrane transport The process in which urea, the water-soluble compound H2N-CO-NH2, is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. CHEBI:84553 2-demethylmenaquinol-13 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84553 GO:0007370 ventral furrow formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007370 Formation of a ventral indentation (furrow) from the blastoderm epithelium, which is internalized to form a tube in the interior of the embryo, marking the start of gastrulation. GO:0071917 triose-phosphate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071917 Enables the transfer of a triose phosphate from one side of a membrane to the other. CHEBI:84552 menaquinol-13 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84552 CHEBI:60599 mu-opioid agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60599 GO:0071916 dipeptide transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071916 dipeptide transporter activity Enables the transfer of a dipeptide from one side of a membrane to the other. A dipeptide is a combination of two amino acids linked together by a peptide (-CO-NH-) bond. CHEBI:84551 2-demethylmenaquinol-12 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84551 CHEBI:59573 (1->2)-beta-D-mannan biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59573 GO:0071915 protein-lysine lysylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071915 protein amino acid lysylation The addition of lysine group to a lysine residue in a protein, producing N6-(lysyl)-L-lysine. This modification is observed in, and is probably unique to, translation elongation factor P (EF-P). CHEBI:60598 opioid agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60598 CHEBI:84550 menaquinol-12 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84550 GO:0071914 prominosome biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071914 prominin-containing extracellular membrane vesicle An extracellular membrane-bounded vesicle that contains prominin proteins (in mouse Prom1/CD33 or Prom2) and are found in body fluids including ventricular fluid, saliva, urine and seminal fluid. In the ventricular fluid of the developing mouse brain two major classes of these particles have been observed (P2 particles of 500-1000 nm and P4 particles of 50-80 nm) which likely originate from microvilli, primary cilia and/or the midbody of neuroepithelial cells. The physiological role is not known. GO:0046979 TAP2 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046979 Interacting selectively and non-covalently with the TAP2 subunit of TAP (transporter associated with antigen processing) protein. GO:0071913 citrate secondary active transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071913 citrate carrier activity Enables the transfer of citrate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. GO:0046978 TAP1 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046978 Interacting selectively and non-covalently with the TAP1 subunit of TAP (transporter associated with antigen processing) protein. GO:0071912 asynchronous neurotransmitter secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071912 Release of neurotransmitter at the synapse that persists for tens to hundreds of milliseconds after action potential invasion. GO:0071911 synchronous neurotransmitter secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071911 Release of neurotransmitter at the synapse that lasts for just a few milliseconds after action potential invasion. GO:0046977 TAP binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046977 Interacting selectively and non-covalently with TAP protein, transporter associated with antigen processing protein. TAP protein is a heterodimeric peptide transporter consisting of the subunits TAP1 and TAP2. GO:0071910 determination of liver left/right asymmetry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071910 Determination of the asymmetric location of the liver with respect to the left and right halves of the organism. GO:0032302 MutSbeta complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032302 MSH2/MSH3 complex|MMR complex A heterodimer involved in binding to and correcting insertion/deletion mutations. In human the complex consists of two subunits, MSH2 and MSH3. GO:0032301 MutSalpha complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032301 MSH2/MSH6 complex|MMR complex A heterodimer involved in the recognition and repair of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MSH2 and MSH6. GO:0032300 mismatch repair complex biolink:CellularComponent go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0032300 Any complex formed of proteins that act in mismatch repair. GO:1900808 fumigaclavine C catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900808 fumigaclavine C catabolism|fumigaclavine C degradation|fumigaclavine C breakdown The chemical reactions and pathways resulting in the breakdown of fumigaclavine C. GO:1900807 fumigaclavine C metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900807 fumigaclavine C metabolism The chemical reactions and pathways involving fumigaclavine C. GO:1900809 fumigaclavine C biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900809 fumigaclavine C formation|fumigaclavine C biosynthesis|fumigaclavine C anabolism|fumigaclavine C synthesis The chemical reactions and pathways resulting in the formation of fumigaclavine C. GO:1900815 monodictyphenone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900815 monodictyphenone anabolism|monodictyphenone synthesis|monodictyphenone formation|monodictyphenone biosynthesis The chemical reactions and pathways resulting in the formation of monodictyphenone. GO:1900814 monodictyphenone catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900814 monodictyphenone degradation|monodictyphenone catabolism|monodictyphenone breakdown The chemical reactions and pathways resulting in the breakdown of monodictyphenone. GO:1900817 ochratoxin A catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900817 Ochratoxin A catabolic process|ochratoxin A catabolism|Ochratoxin A catabolism|Ochratoxin A degradation|ochratoxin A degradation|Ochratoxin A breakdown|ochratoxin A breakdown The chemical reactions and pathways resulting in the breakdown of ochratoxin A. GO:1900816 ochratoxin A metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900816 Ochratoxin A metabolism|Ochratoxin A metabolic process The chemical reactions and pathways involving ochratoxin A. GO:1900811 helvolic acid catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900811 Fumigacin catabolic process|helvolic acid catabolism|Fumigacin catabolism|helvolic acid degradation|Fumigacin degradation|helvolic acid breakdown|Fumigacin breakdown The chemical reactions and pathways resulting in the breakdown of helvolic acid. GO:0007339 binding of sperm to zona pellucida biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007339 ZPG binding The process in which the sperm binds to the zona pellucida glycoprotein layer of the egg. The process begins with the attachment of the sperm plasma membrane to the zona pellucida and includes attachment of the acrosome inner membrane to the zona pellucida after the acrosomal reaction takes place. GO:0007338 single fertilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007338 zygote biosynthesis|zygote formation The union of male and female gametes to form a zygote. GO:1900810 helvolic acid metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900810 helvolic acid metabolism|Fumigacin metabolism|Fumigacin metabolic process The chemical reactions and pathways involving helvolic acid. GO:1900813 monodictyphenone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900813 monodictyphenone metabolism The chemical reactions and pathways involving monodictyphenone. GO:0007337 obsolete unilateral process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007337 unilateral process OBSOLETE. (Was not defined before being made obsolete). GO:1900812 helvolic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900812 helvolic acid anabolism|Fumigacin anabolism|helvolic acid synthesis|Fumigacin synthesis|helvolic acid formation|Fumigacin formation|helvolic acid biosynthesis|Fumigacin biosynthetic process|Fumigacin biosynthesis The chemical reactions and pathways resulting in the formation of helvolic acid. GO:0007336 obsolete bilateral process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007336 bilateral process OBSOLETE. (Was not defined before being made obsolete). GO:0046987 N-acetyllactosamine beta-1,3-glucuronosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046987 galactosyl beta-1,4 N-acetylglucosamine beta-1,3 glucuronosyltransferase activity Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-D-glucuronic acid to N-acetyllactosamine (galactosyl beta-1,4-N-acetylglucosamine). GO:0007335 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007335 GO:0046986 negative regulation of hemoglobin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046986 negative regulation of haemoglobin biosynthetic process|negative regulation of haemoglobin biosynthesis|down regulation of hemoglobin biosynthetic process|downregulation of hemoglobin biosynthetic process|negative regulation of hemoglobin biosynthesis|negative regulation of hemoglobin anabolism|down-regulation of hemoglobin biosynthetic process|negative regulation of hemoglobin synthesis|negative regulation of hemoglobin formation|inhibition of hemoglobin biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin. GO:0007334 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007334 GO:0046985 positive regulation of hemoglobin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046985 positive regulation of haemoglobin biosynthesis|positive regulation of haemoglobin biosynthetic process|up regulation of hemoglobin biosynthetic process|activation of hemoglobin biosynthetic process|positive regulation of hemoglobin biosynthesis|stimulation of hemoglobin biosynthetic process|positive regulation of hemoglobin anabolism|up-regulation of hemoglobin biosynthetic process|positive regulation of hemoglobin synthesis|positive regulation of hemoglobin formation|upregulation of hemoglobin biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin. GO:0007333 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007333 GO:0046984 regulation of hemoglobin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046984 regulation of hemoglobin biosynthesis|regulation of haemoglobin biosynthesis|regulation of haemoglobin biosynthetic process|regulation of hemoglobin anabolism|regulation of hemoglobin synthesis|regulation of hemoglobin formation Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin. GO:0007332 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007332 GO:0007331 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007331 GO:0046983 protein dimerization activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046983 The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits. GO:0046982 protein heterodimerization activity biolink:MolecularActivity go-plus goslim_chembl http://purl.obolibrary.org/obo/GO_0046982 Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer. GO:0007330 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007330 GO:0046981 beta-1,4-mannosylglycolipid beta-1,3-N-acetylglucosaminyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046981 UDP-N-acetylglucosamine:beta-D-mannosyl-glycolipid beta-1,3-N-acetylglucosaminyltransferase activity Catalysis of the transfer of N-acetylglucosamine (GlcNAc) in a beta-1,3 linkage to the mannose(beta-1,4)Glc disaccharide core of glycolipids. GO:0046980 tapasin binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046980 TAPBP binding|TAP binding protein binding Interacting selectively and non-covalently with tapasin, a member of the MHC class I loading complex which bridges the TAP peptide transporter to class I molecules. CHEBI:59564 thermospermine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59564 CHEBI:142839 enolate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_142839 CHEBI:35596 (+)-pulegone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35596 GO:0071949 FAD binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071949 oxidized flavin adenine dinucleotide binding|oxidized flavine-adenine dinucleotide binding Interacting selectively and non-covalently with the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes. CHEBI:59562 5-hydroxyisouric acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59562 GO:0071948 activation-induced B cell apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071948 activated B cell apoptosis|activation-induced cell death of B lymphocytes|activation-induced B cell apoptosis|activation-induced B-cell apoptosis|antigen-driven apoptosis|activation-induced cell death of B cells|activation-induced cell death of B-lymphocytes|AICD|activation-induced cell death of B-cells B cell apoptotic process that occurs upon engagement of either the B cell receptor or CD40. Engagement of either receptor, but not both, leads to expression of fas or related receptors that make the B cell susceptible to fas-ligand mediated death. CHEBI:84561 2,4-dinitrophenol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84561 CHEBI:59561 diamino acid anion biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59561 CHEBI:59560 sapropterin biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59560 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071947 The removal of one or more ubiquitin groups from a protein as part of a process of ubiquitin-dependent protein catabolism. GO:0071946 cis-acting DNA replication termination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071946 cis acting DNA replication termination A DNA replication termination process that is initiated by protein binding to a binding site on the same chromosome, but remote from the termination site, via DNA looping or chromosome kissing. GO:0071945 regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071945 regulation of flagellar cell motility by regulation of motor speed|regulation of bacterial-type flagellar cell motility by regulation of motor speed|regulation of bacterial-type flagellum cell motility by regulation of motor speed A process that modulates flagellum-dependent motility in bacteria by modulating the speed or direction of rotation of a rotary flagellar motor, mediated by interactions between the braking protein. GO:0046989 galactosyl beta-1,3 N-acetylgalactosamine beta-1,3-glucuronosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046989 Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-GlcUA to the disaccharide galactosyl beta-1,3 N-acetylgalactosamine, a common component of glycoproteins and glycolipids. GO:0071944 cell periphery biolink:CellularComponent go-plus goslim_flybase_ribbon http://purl.obolibrary.org/obo/GO_0071944 The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures. GO:0046988 asioloorosomucoid beta-1,3-glucuronosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046988 Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-GlcUA to asioloorosomucoid. GO:0071943 Myc-Max complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071943 A transcription factor complex that consists of a heterodimer of the bHLH-ZIP proteins Myc and Max. GO:0071942 XPC complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071942 A nucleotide-excision repair complex that is involved in damage sensing during global genome nucleotide excision repair (GG-NER). It is part of the pre-incision (or initial recognition) complex bound to sites of DNA damage. In human, it is composed of XPC, RAD23B and CETN2. GO:0071941 nitrogen cycle metabolic process biolink:BiologicalProcess go-plus goslim_generic|goslim_pombe|goslim_chembl http://purl.obolibrary.org/obo/GO_0071941 Wikipedia:Nitrogen_cycle A nitrogen compound metabolic process that contributes to the nitrogen cycle. The nitrogen cycle is a series of metabolic pathways by which nitrogen is converted between various forms and redox states; it encompasses pathways in which nitrogen is acted upon directly, such as nitrification, denitrification, nitrogen fixation, and mineralization. GO:0071940 fungal-type cell wall assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071940 fungal-type cell wall formation The aggregation, arrangement and bonding together of a set of components to form a fungal-type cell wall. GO:1900819 orlandin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900819 orlandin metabolism The chemical reactions and pathways involving orlandin. CHEBI:35593 4H-pyran biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35593 GO:1900818 ochratoxin A biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900818 Ochratoxin A anabolism|Ochratoxin A synthesis|Ochratoxin A formation|Ochratoxin A biosynthesis|Ochratoxin A biosynthetic process The chemical reactions and pathways resulting in the formation of ochratoxin A. CHEBI:35592 2H-pyran biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35592 CHEBI:35594 pyran biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35594 GO:0046990 N-hydroxyarylamine O-acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046990 EC:2.3.1.118|MetaCyc:2.3.1.118-RXN|RHEA:20277 N-hydroxy-2-aminofluorene-O-acetyltransferase activity|acetyl-CoA:N-hydroxyarylamine O-acetyltransferase activity|arylhydroxamate N,O-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + an N-hydroxyarylamine = CoA + an N-acetoxyarylamine. GO:1900826 negative regulation of membrane depolarization during cardiac muscle cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900826 down regulation of membrane depolarization during cardiac muscle cell action potential|downregulation of membrane depolarization during cardiac muscle cell action potential|down-regulation of membrane depolarization during of cardiac muscle cell action potential|inhibition of membrane depolarization during cardiac muscle cell action potential Any process that stops, prevents or reduces the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential. GO:1900825 regulation of membrane depolarization during cardiac muscle cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900825 Any process that modulates the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential. GO:1900828 D-tyrosine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900828 D-tyrosine metabolism The chemical reactions and pathways involving D-tyrosine. GO:1900827 positive regulation of membrane depolarization during cardiac muscle cell action potential biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900827 up regulation of membrane depolarization during cardiac muscle cell action potential|activation of membrane depolarization during cardiac muscle cell action potential|up-regulation of membrane depolarization during cardiac muscle cell action potential|upregulation of membrane depolarization during cardiac muscle cell action potential Any process that activates or increases the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential. GO:1900822 regulation of ergot alkaloid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900822 regulation of ergot alkaloid synthesis|regulation of ergot alkaloid formation|regulation of ergot alkaloid biosynthesis|regulation of ergot alkaloid anabolism Any process that modulates the frequency, rate or extent of ergot alkaloid biosynthetic process. GO:0007349 cellularization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007349 The separation of a multi-nucleate cell or syncytium into individual cells. An example of this is found in Drosophila melanogaster embryo development. GO:1900821 orlandin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900821 orlandin synthesis|orlandin formation|orlandin biosynthesis|orlandin anabolism The chemical reactions and pathways resulting in the formation of orlandin. GO:1900824 positive regulation of ergot alkaloid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900824 positive regulation of ergot alkaloid formation|up regulation of ergot alkaloid formation|up-regulation of ergot alkaloid biosynthetic process|up-regulation of ergot alkaloid biosynthesis|upregulation of ergot alkaloid anabolism|upregulation of ergot alkaloid synthesis|upregulation of ergot alkaloid formation|upregulation of ergot alkaloid biosynthesis|upregulation of ergot alkaloid biosynthetic process|up-regulation of ergot alkaloid anabolism|up-regulation of ergot alkaloid synthesis|activation of ergot alkaloid anabolism|up-regulation of ergot alkaloid formation|up regulation of ergot alkaloid biosynthetic process|up regulation of ergot alkaloid biosynthesis|activation of ergot alkaloid synthesis|activation of ergot alkaloid biosynthetic process|positive regulation of ergot alkaloid anabolism|positive regulation of ergot alkaloid biosynthesis|activation of ergot alkaloid formation|up regulation of ergot alkaloid anabolism|positive regulation of ergot alkaloid synthesis|activation of ergot alkaloid biosynthesis|up regulation of ergot alkaloid synthesis Any process that activates or increases the frequency, rate or extent of ergot alkaloid biosynthetic process. GO:0007348 regulation of syncytial blastoderm mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007348 syncytial blastoderm cell cycle modulation|modulation of syncytial blastoderm cell cycle progression|regulation of syncytial blastoderm cell cycle|regulation of syncytial blastoderm cell cycle progression|syncytial blastoderm cell cycle regulation|regulation of progression through syncytial blastoderm mitotic cell cycle|syncytial blastoderm cell cycle regulator A cell cycle process that modulates the rate or extent of the progression through the syncytial blastoderm mitotic cell cycle. GO:0007347 regulation of preblastoderm mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007347 regulation of preblastoderm mitotic cell cycle progression|preblastoderm mitotic cell cycle modulation|modulation of preblastoderm mitotic cell cycle progression|regulation of progression through preblastoderm mitotic cell cycle|preblastoderm mitotic cell cycle regulator|preblastoderm mitotic cell cycle regulation A cell cycle process that modulates the rate or extent of the progression through the preblastoderm mitotic cell cycle. GO:1900823 negative regulation of ergot alkaloid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900823 downregulation of ergot alkaloid synthesis|down regulation of ergot alkaloid anabolism|inhibition of ergot alkaloid biosynthetic process|downregulation of ergot alkaloid formation|down regulation of ergot alkaloid synthesis|inhibition of ergot alkaloid anabolism|inhibition of ergot alkaloid biosynthesis|down regulation of ergot alkaloid formation|inhibition of ergot alkaloid synthesis|inhibition of ergot alkaloid formation|down regulation of ergot alkaloid biosynthetic process|down regulation of ergot alkaloid biosynthesis|downregulation of ergot alkaloid biosynthetic process|downregulation of ergot alkaloid biosynthesis|down-regulation of ergot alkaloid anabolism|negative regulation of ergot alkaloid anabolism|down-regulation of ergot alkaloid synthesis|negative regulation of ergot alkaloid synthesis|down-regulation of ergot alkaloid formation|negative regulation of ergot alkaloid formation|down-regulation of ergot alkaloid biosynthesis|down-regulation of ergot alkaloid biosynthetic process|negative regulation of ergot alkaloid biosynthesis|downregulation of ergot alkaloid anabolism Any process that stops, prevents or reduces the frequency, rate or extent of ergot alkaloid biosynthetic process. GO:0007346 regulation of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007346 mitotic cell cycle modulation|regulation of mitotic cell cycle progression|mitotic cell cycle regulation|modulation of mitotic cell cycle progression|regulation of progression through mitotic cell cycle|mitotic cell cycle regulator Any process that modulates the rate or extent of progress through the mitotic cell cycle. GO:0046998 (S)-usnate reductase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046998 KEGG_REACTION:R07345|MetaCyc:1.1.1.199-RXN|EC:1.1.1.199|RHEA:21876 L-usnic acid dehydrogenase activity|reduced-(S)-usnate:NAD+ oxidoreductase (ether-bond-forming) Catalysis of the reaction: (6R)-2-acetyl-6-(3-acetyl-2,4,6-trihydroxy-5-methylphenyl)-3-hydroxy-6-methylcyclohexa-2,4-dien-1-one + NAD(+) = (S)-usnate + 2 H(+) + NADH. GO:0007345 obsolete embryogenesis and morphogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007345 embryogenesis and morphogenesis OBSOLETE. Formation and development of an embryo and its organized structures. GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046997 EC:1.5.8.- Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces a flavin. GO:0007344 pronuclear fusion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007344 The merging of two pronuclei in a fertilized egg to fuse and produce a single zygotic genome. GO:1900820 orlandin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900820 orlandin catabolism|orlandin degradation|orlandin breakdown The chemical reactions and pathways resulting in the breakdown of orlandin. GO:0046996 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046996 EC:1.14.21.- oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NADH or NADPH as one donor, and the other dehydrogenated Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and the latter donor is dehydrogenated. GO:0046995 oxidoreductase activity, acting on hydrogen as donor, with other known acceptors biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046995 EC:1.12.98.- Catalysis of an oxidation-reduction (redox) reaction in which hydrogen reduces a known acceptor other than a cytochrome, an iron-sulfur protein, NAD, NADP, or a quinone or similar compound. GO:0007343 egg activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007343 Wikipedia:Egg_activation The process in which the egg becomes metabolically active, initiates protein and DNA synthesis and undergoes structural changes to its cortex and/or cytoplasm. GO:0046994 oxidoreductase activity, acting on hydrogen as donor, with a quinone or similar compound as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046994 EC:1.12.5.- Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces quinone or similar compound. CHEBI:84579 3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1,5-dioxo-octahydroinden-4-yl]propanoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84579 GO:0007342 fusion of sperm to egg plasma membrane involved in single fertilization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007342 sperm-oocyte fusion The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of single fertilization. In sperm with flagella, binding occurs at the posterior (post-acrosomal) region of the sperm head. GO:0046993 oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046993 EC:1.21.3.- Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y and the acceptor is oxygen. GO:0007341 penetration of zona pellucida biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007341 The infiltration by sperm of the zona pellucida to reach the oocyte. The process involves digestive enzymes from a modified lysosome called the acrosome, situated at the head of the sperm. GO:0046992 oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046992 EC:1.21.-.- oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with other acceptors Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y. GO:0007340 acrosome reaction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007340 Wikipedia:Acrosome_reaction The discharge, by sperm, of a single, anterior secretory granule following the sperm's attachment to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents into the zona pellucida. CHEBI:84576 (25S)-3beta-hydroxy-5-cholesten-26-oyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84576 GO:0046991 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046991 GO:0071939 vitamin A import biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071939 vitamin A uptake The directed movement of vitamin A into a cell or organelle. Vitamin A is any of several retinoid derivatives of beta-carotene, primarily retinol, retinal, or retinoic acid. GO:0071938 vitamin A transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071938 vitamin A uptake and transport The directed movement any form of vitamin A into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Vitamin A is any of several retinoid derivatives of beta-carotene, primarily retinol, retinal, or retinoic acid. CHEBI:84572 27-O-demethylrifamycin SV(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84572 GO:0071937 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0071937 CHEBI:84571 rifamycin SV(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84571 GO:0071936 coreceptor activity involved in Wnt signaling pathway biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071936 coreceptor activity involved in Wnt receptor signalling pathway|Wnt co-receptor activity|coreceptor activity involved in Wnt-activated signaling pathway|coreceptor activity involved in Wnt receptor signaling pathway In cooperation with a primary Wnt receptor, initiating a change in cell activity through the Wnt signaling pathway. CHEBI:142823 andrastin A(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142823 CHEBI:166856 hydroxytrimethylaminium biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_166856 GO:0071935 octopamine signaling pathway involved in response to food biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071935 octopamine signalling pathway involved in response to food The series of molecular signals initiated by binding of octopamine to a receptor on the surface of the target cell that contributes to a response to a food stimulus. CHEBI:142822 andrastin B(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142822 GO:0071934 thiamine transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071934 thiamin transmembrane transport|vitamin B1 transmembrane transport|thiamine membrane transport The process in which thiamine is transported across a membrane. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver. CHEBI:142821 andrastin C(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142821 GO:0046999 regulation of conjugation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046999 Any process that modulates the rate or frequency of conjugation, the union or introduction of genetic information from compatible mating types that results in a genetically different individual. GO:0071933 Arp2/3 complex binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071933 Interacting selectively and non-covalently with an Arp2/3 complex, a protein complex that contains two actin-related proteins, Arp2 and Arp3, and five novel proteins (ARPC1-5). GO:0071932 replication fork reversal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071932 Replication fork processing that involves the unwinding of blocked forks to form four-stranded structures resembling Holliday junctions, which are subsequently resolved. GO:0071931 positive regulation of transcription involved in G1/S transition of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071931 positive regulation of transcription from RNA polymerase II promoter during G1/S phase of mitotic cell cycle|positive regulation of transcription from RNA polymerase II promoter involved in G1/S transition of mitotic cell cycle Any process that activates or increases transcription as part of the G1/S transition of the mitotic cell cycle. GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071930 negative regulation of transcription from RNA polymerase II promoter involved in G1/S transition of mitotic cell cycle|negative regulation of transcription from RNA polymerase II promoter during G1/S phase of mitotic cell cycle Any process that stop, prevents or decreases transcription as part of the G1/S transition of the mitotic cell cycle. CHEBI:59558 medium-chain fatty acid anion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59558 GO:1900829 D-tyrosine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900829 D-tyrosine degradation|D-tyrosine breakdown|D-tyrosine catabolism The chemical reactions and pathways resulting in the breakdown of D-tyrosine. CHEBI:59554 medium-chain fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59554 GO:1900837 regulation of fumigaclavine C biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900837 regulation of fumigaclavine C anabolism|regulation of fumigaclavine C synthesis|regulation of fumigaclavine C biosynthesis|regulation of fumigaclavine C formation Any process that modulates the frequency, rate or extent of fumigaclavine C biosynthetic process. GO:1900836 positive regulation of emericellin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900836 Any process that activates or increases the frequency, rate or extent of emericellin biosynthetic process. GO:0007319 negative regulation of oskar mRNA translation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007319 down regulation of oskar mRNA translation|inhibition of oskar mRNA translation|down-regulation of oskar mRNA translation|downregulation of oskar mRNA translation Any process that stops, prevents or reduces the rate that oskar mRNAs are effectively translated into protein. GO:1900839 positive regulation of fumigaclavine C biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900839 upregulation of fumigaclavine C biosynthetic process|up-regulation of fumigaclavine C biosynthetic process|up regulation of fumigaclavine C biosynthetic process Any process that activates or increases the frequency, rate or extent of fumigaclavine C biosynthetic process. GO:1900838 negative regulation of fumigaclavine C biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900838 inhibition of fumigaclavine C biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of fumigaclavine C biosynthetic process. GO:0007318 pole plasm protein localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007318 establishment and maintenance of pole plasm protein localization|oocyte pole plasm protein localization|pole plasm protein localisation Any process in which a protein is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster. GO:0007317 regulation of pole plasm oskar mRNA localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007317 regulation of oocyte pole plasm oskar mRNA localization|regulation of pole plasm oskar mRNA localisation Any process that modulates the frequency, rate or extent of the process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm. GO:1900833 D-leucine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900833 D-leucine anabolism|D-leucine synthesis|D-leucine formation|D-leucine biosynthesis The chemical reactions and pathways resulting in the formation of D-leucine. GO:1900832 D-leucine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900832 D-leucine degradation|D-leucine breakdown|D-leucine catabolism The chemical reactions and pathways resulting in the breakdown of D-leucine. GO:0007316 pole plasm RNA localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007316 pole plasm RNA localisation|establishment and maintenance of pole plasm RNA localization|oocyte pole plasm RNA localization Any process in which RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster. GO:1900835 negative regulation of emericellin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900835 down-regulation of emericellin biosynthetic process|downregulation of emericellin biosynthetic process|down regulation of emericellin biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of emericellin biosynthetic process. GO:0007315 pole plasm assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007315 Establishment of the specialized cytoplasm found at the poles of the egg. An example of this is found in Drosophila melanogaster. GO:1900834 regulation of emericellin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900834 regulation of emericellin formation|regulation of Variecoxanthone B formation|regulation of emericellin biosynthesis|regulation of emericellin anabolism|regulation of Variecoxanthone B anabolism|regulation of Variecoxanthone B biosynthesis|regulation of Variecoxanthone B biosynthetic process|regulation of emericellin synthesis|regulation of Variecoxanthone B synthesis Any process that modulates the frequency, rate or extent of emericellin biosynthetic process. GO:0007314 oocyte anterior/posterior axis specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007314 oocyte anterior/posterior axis determination Polarization of the oocyte along its anterior-posterior axis. An example of this is found in Drosophila melanogaster. GO:0007313 maternal specification of dorsal/ventral axis, oocyte, soma encoded biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007313 maternal determination of dorsal/ventral axis, oocyte, soma encoded|maternal specification of dorsoventral axis, oocyte, soma encoded|maternal specification of dorsal-ventral axis, oocyte, soma encoded Polarization of the oocyte along the dorsal-ventral axis, by a gene product encoded by somatic cells. An example of this is found in Drosophila melanogaster. GO:0007312 oocyte nucleus migration involved in oocyte dorsal/ventral axis specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007312 establishment of oocyte nucleus localization during oocyte axis determination|oocyte nucleus migration during oocyte axis specification|oocyte axis determination, oocyte nucleus migration|establishment of oocyte nucleus localization involved in oocyte dorsal/ventral axis specification|establishment of localization of oocyte nucleus during oocyte axis determination|oocyte axis determination, positioning of nucleus|oocyte axis determination, establishment of localization of nucleus|establishment of oocyte nucleus localization involved in oocyte dorsal-ventral axis specification|establishment of oocyte nucleus localisation involved in oocyte dorsal/ventral axis specification|oocyte axis determination, oocyte nuclear migration|oocyte axis determination, establishment of position of nucleus|oocyte axis determination, establishment of oocyte nucleus localization|nucleus positioning in oocyte during oocyte axis determination|establishment of oocyte nucleus localization involved in oocyte dorsal/ventral axis determination|oocyte nuclear migration during oocyte axis determination|oocyte nucleus migration during oocyte axis determination|establishment of oocyte nucleus localization involved in oocyte dorsoventral axis specification|oocyte nucleus positioning during oocyte axis determination The directed movement of the oocyte nucleus within the cell as part of the establishment and maintenance of the dorsal/ventral axis of the oocyte. An example of this is found in Drosophila melanogaster. GO:0007311 maternal specification of dorsal/ventral axis, oocyte, germ-line encoded biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007311 maternal determination of dorsal/ventral axis, oocyte, germ-line encoded|maternal specification of dorsal-ventral axis, oocyte, germ-line encoded|maternal specification of dorsoventral axis, oocyte, germ-line encoded Polarization of the oocyte along the dorsal-ventral axis, by a gene product encoded by cells of the germ line. An example of this is found in Drosophila melanogaster. GO:1900831 D-leucine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900831 D-leucine metabolism The chemical reactions and pathways involving D-leucine. GO:1900830 D-tyrosine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900830 D-tyrosine biosynthesis|D-tyrosine anabolism|D-tyrosine synthesis|D-tyrosine formation The chemical reactions and pathways resulting in the formation of D-tyrosine. GO:0007310 oocyte dorsal/ventral axis specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007310 oocyte dorsal-ventral axis specification|oocyte dorsoventral axis specification|oocyte dorsal/ventral axis determination The establishment, maintenance and elaboration of the dorsal/ventral axis of the oocyte. An example of this is found in Drosophila melanogaster. CHEBI:84589 mitomycin A(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84589 UBERON:2000440 superior raphe nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_2000440 anterior raphe nucleus CHEBI:84588 trans-2,3-unsaturated fatty aldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84588 CHEBI:84587 2,3-saturated fatty aldehyde biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84587 CHEBI:59541 coenzyme gamma-F420-2(4-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59541 CHEBI:84584 3-oxodotriacontanoyl-CoA biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84584 GO:0071969 fungal-type cell wall (1->3)-beta-D-glucan metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071969 fungal-type cell wall beta-1,3 glucan metabolism|fungal-type cell wall 1,3-beta-glucan metabolism|fungal-type cell wall beta-1,3 glucan metabolic process|fungal-type cell wall 1,3-beta-D-glucan metabolic process The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of fungi. CHEBI:35579 3H-indole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35579 GO:0071968 lipid A-core heptosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071968 MetaCyc:RXN0-5127|RHEA:30019 Catalysis of the reaction: galactosyl-glucosyl3-heptosyl3-KDO2-lipid A-bisphosphate + ADP-L-glycero-beta-D-manno-heptose = lipid A-core + ADP + H+. CHEBI:84581 1,2,2'-trilinoleoyl-,1'-monolysocardiolipin biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84581 GO:0071967 lipopolysaccharide core heptosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071967 MetaCyc:RXN0-5122|RHEA:29923 LPS core heptosyltransferase activity Catalysis of the reaction: glucosyl-heptosyl2-KDO2-lipid A-phosphate + ADP-L-glycero-beta-D-manno-heptose = glucosyl-heptosyl3-KDO2-lipid A-phosphate + ADP + H+. CHEBI:84580 dinitroanisoles biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84580 GO:0071966 fungal-type cell wall polysaccharide metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071966 The chemical reactions and pathways involving the polysaccharides which make up the fungal-type cell wall. GO:0071965 multicellular organismal locomotion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071965 Locomotion in a multicellular organism, i.e. self-propelled movement of a multicellular organism from one location to another. GO:0071964 establishment of cell polarity regulating cell shape biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071964 Any cellular process that results in the specification or formation of a polarized intracellular organization or cell growth pattern that regulates the shape of a cell. CHEBI:59549 essential fatty acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59549 GO:0071963 establishment or maintenance of cell polarity regulating cell shape biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071963 Any cellular process that results in the specification, formation or maintenance of a polarized intracellular organization or cell growth patterns that regulate the shape of a cell. GO:0071962 mitotic sister chromatid cohesion, centromeric biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071962 centromeric mitotic sister chromatin cohesion|sister chromatid cohesion at centromere at mitosis|mitotic sister chromatid cohesion at centromere The cell cycle process in which centromeres of sister chromatids are joined during mitosis. GO:0071961 mitotic sister chromatid cohesion, arms biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071961 mitotic sister chromatid cohesion along arms|sister chromatid cohesion along arms at mitosis The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the chromosome arms during mitosis. CHEBI:35571 mancude organic heterocyclic parent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35571 CHEBI:59546 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59546 CHEBI:59545 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59545 GO:0071960 maintenance of mitotic sister chromatid cohesion, centromeric biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071960 maintenance of sister chromatin cohesion at centromere at mitosis|maintenance of centromeric mitotic sister chromatin cohesion|maintenance of mitotic sister chromatin cohesion at centromere The process in which the association between sister chromatids of a replicated chromosome along the length of the centromeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle. CHEBI:35570 mancude organic heterobicyclic parent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35570 CHEBI:59544 phosphoantigen biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59544 CHEBI:35573 organic mancude parent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35573 CHEBI:59543 coenzyme F420-1(3-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59543 GO:1900848 positive regulation of naphtho-gamma-pyrone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900848 up-regulation of naphtho-gamma-pyrone biosynthetic process|upregulation of naphtho-gamma-pyrone biosynthetic process|up regulation of naphtho-gamma-pyrone biosynthetic process|activation of naphtho-gamma-pyrone biosynthetic process Any process that activates or increases the frequency, rate or extent of naphtho-gamma-pyrone biosynthetic process. GO:1900847 negative regulation of naphtho-gamma-pyrone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900847 inhibition of naphtho-gamma-pyrone biosynthetic process|down regulation of naphtho-gamma-pyrone biosynthetic process|downregulation of naphtho-gamma-pyrone biosynthetic process|down-regulation of naphtho-gamma-pyrone biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of naphtho-gamma-pyrone biosynthetic process. GO:0007329 positive regulation of transcription from RNA polymerase II promoter by pheromones biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007329 up-regulation of transcription from RNA polymerase II promoter by pheromones|positive regulation of transcription from Pol II promoter by pheromones|upregulation of transcription from RNA polymerase II promoter by pheromones|up regulation of transcription from RNA polymerase II promoter by pheromones|activation of transcription from RNA polymerase II promoter by pheromones|stimulation of transcription from RNA polymerase II promoter by pheromones Any process involving pheromones that activates or increases the rate of transcription from an RNA polymerase II promoter. GO:1900849 regulation of pseurotin A biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900849 regulation of Pseurotin anabolism|regulation of pseurotin A formation|regulation of Pseurotin synthesis|regulation of Pseurotin formation|regulation of pseurotin A biosynthesis|regulation of Pseurotin biosynthesis|regulation of Pseurotin biosynthetic process|regulation of pseurotin A anabolism|regulation of pseurotin A synthesis Any process that modulates the frequency, rate or extent of pseurotin A biosynthetic process. GO:1900844 negative regulation of monodictyphenone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900844 down regulation of monodictyphenone biosynthetic process|downregulation of monodictyphenone biosynthetic process|down-regulation of monodictyphenone biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of monodictyphenone biosynthetic process. GO:0007328 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007328 GO:1900843 regulation of monodictyphenone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900843 regulation of monodictyphenone biosynthesis|regulation of monodictyphenone anabolism|regulation of monodictyphenone synthesis|regulation of monodictyphenone formation Any process that modulates the frequency, rate or extent of monodictyphenone biosynthetic process. GO:0007327 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007327 GO:1900846 regulation of naphtho-gamma-pyrone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900846 regulation of naphtho-gamma-pyrone synthesis|regulation of naphtho-gamma-pyrones biosynthesis|regulation of naphtho-gamma-pyrones biosynthetic process|regulation of naphtho-gamma-pyrone formation|regulation of naphtho-gamma-pyrone biosynthesis|regulation of naphtho-gamma-pyrones anabolism|regulation of naphtho-gamma-pyrones synthesis|regulation of naphtho-gamma-pyrones formation|regulation of naphtho-gamma-pyrone anabolism Any process that modulates the frequency, rate or extent of naphtho-gamma-pyrone biosynthetic process. GO:0007326 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007326 GO:1900845 positive regulation of monodictyphenone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900845 upregulation of monodictyphenone biosynthetic process Any process that activates or increases the frequency, rate or extent of monodictyphenone biosynthetic process. GO:0007325 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007325 GO:1900840 regulation of helvolic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900840 Any process that modulates the frequency, rate or extent of helvolic acid biosynthetic process. GO:0007324 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007324 GO:0007323 peptide pheromone maturation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007323 pheromone processing The generation of a mature, active peptide pheromone via processes unique to its processing and modification. An example of this process is found in Saccharomyces cerevisiae. GO:1900842 positive regulation of helvolic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900842 up regulation of helvolic acid biosynthetic process|upregulation of helvolic acid biosynthetic process|up-regulation of helvolic acid biosynthetic process Any process that activates or increases the frequency, rate or extent of helvolic acid biosynthetic process. GO:0007322 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007322 GO:1900841 negative regulation of helvolic acid biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900841 downregulation of helvolic acid biosynthetic process|down regulation of helvolic acid biosynthetic process|down-regulation of helvolic acid biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of helvolic acid biosynthetic process. GO:0007321 sperm displacement biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007321 The physical displacement of sperm stored from previous mating encounters. GO:0007320 insemination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007320 Wikipedia:Insemination The introduction of semen or sperm into the genital tract of a female. CHEBI:84599 all-trans-dodecaprenyl diphosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84599 CHEBI:35586 1H-purine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35586 CHEBI:59531 F420-0(2-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59531 CHEBI:11596 2-hydroxyglutarate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_11596 UBERON:2000425 anterior lateral line nerve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_2000425 rostral lateral line nerve Cranial nerve which enters the brain between cranial nerves VI and VII; contains afferents and sensory efferents to the anterior lateral line ganglia. CHEBI:35588 3H-purine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35588 CHEBI:142803 2,3-cis-enoyl CoA(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142803 GO:0071959 maintenance of mitotic sister chromatid cohesion, arms biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071959 maintenance of sister chromatin cohesion along arms at mitosis|maintenance of mitotic sister chromatin cohesion along arms The process in which the association between sister chromatids of a replicated chromosome along the length of the chromosome arms, is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle. CHEBI:11594 2-coumarate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_11594 GO:0071958 new mitotic spindle pole body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071958 new SPB The spindle pole body that is formed by spindle pole body duplication, and to which proteins involved in mitotic exit signaling (for example, the septation initiation network in fission yeast) localize. CHEBI:35589 9H-purine biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35589 GO:0071957 old mitotic spindle pole body biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071957 old SPB The spindle pole body that exists in a cell prior to spindle pole body duplication. An old spindle pole body segregates to the daughter cell upon mitosis, and lacks active proteins involved in signaling exit from mitosis. CHEBI:84592 7-demethylmitomycin A(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84592 GO:0071956 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0071956 CHEBI:84591 7-demethylmitomycin B(1-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84591 GO:0071955 recycling endosome to Golgi transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071955 The directed movement of substances from recycling endosomes to the Golgi. CHEBI:84590 mitomycin B(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84590 GO:0071954 chemokine (C-C motif) ligand 11 production biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0071954 C-C motif chemokine 11 production|CCL-11 production|eotaxin-1 production|CCL11 production|eotaxin production The appearance of chemokine (C-C motif) ligand 11 (CCL11, also known as eotaxin-1) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. CHEBI:59539 coenzyme alpha-F420-3(5-) biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59539 GO:0071953 elastic fiber biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071953 elastic fibre|elastin fiber An supramolecular fiber that consists of an insoluble core of polymerized tropoelastin monomers and a surrounding mantle of microfibrils. Elastic fibers provide elasticity and recoiling to tissues and organs, and maintain structural integrity against mechanical strain. GO:0071952 conversion of O-phosphoseryl-tRNA to cysteinyl-tRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071952 The modification process that results in the conversion of O-phosphoserine charged on a tRNA(Cys) to cysteinyl-tRNA. CHEBI:35580 N-oxide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35580 CHEBI:59537 coenzyme alpha-F420-3 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59537 GO:0071951 conversion of methionyl-tRNA to N-formyl-methionyl-tRNA biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071951 The modification process that results in the conversion of methionine charged on a tRNA(fMet) to N-formyl-methionine-tRNA(fMet). CHEBI:59536 coenzyme F420-1 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59536 GO:0071950 FADH2 binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071950 reduced flavine-adenine dinucleotide binding|reduced flavin adenine dinucleotide binding Interacting selectively and non-covalently with the reduced form, FADH2, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes. CHEBI:59535 pyrimidoquinolines biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59535 CHEBI:35581 indole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35581 CHEBI:35584 purine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35584 CHEBI:59532 F420-0 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59532 GO:1900859 negative regulation of brevianamide F biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900859 down regulation of brevianamide F biosynthetic process|downregulation of brevianamide F biosynthetic process|down-regulation of brevianamide F biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of brevianamide F biosynthetic process. GO:1900858 regulation of brevianamide F biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900858 regulation of brevianamide F synthesis|regulation of brevianamide F formation|regulation of brevianamide F biosynthesis|regulation of brevianamide F anabolism Any process that modulates the frequency, rate or extent of brevianamide F biosynthetic process. GO:1900855 regulation of fumitremorgin B biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900855 regulation of Lanosulin synthesis|regulation of Lanosulin formation|regulation of fumitremorgin B biosynthesis|regulation of Lanosulin biosynthetic process|regulation of Lanosulin biosynthesis|regulation of fumitremorgin B anabolism|regulation of fumitremorgin B synthesis|regulation of Lanosulin anabolism|regulation of fumitremorgin B formation Any process that modulates the frequency, rate or extent of fumitremorgin B biosynthetic process. GO:1900854 positive regulation of terrequinone A biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900854 upregulation of terrequinone A biosynthetic process|up regulation of terrequinone A biosynthetic process|up-regulation of terrequinone A biosynthetic process Any process that activates or increases the frequency, rate or extent of terrequinone A biosynthetic process. GO:1900857 positive regulation of fumitremorgin B biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900857 up-regulation of fumitremorgin B biosynthetic process|up regulation of fumitremorgin B biosynthetic process|upregulation of fumitremorgin B biosynthetic process Any process that activates or increases the frequency, rate or extent of fumitremorgin B biosynthetic process. GO:1900856 negative regulation of fumitremorgin B biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900856 down-regulation of fumitremorgin B biosynthetic process|downregulation of fumitremorgin B biosynthetic process|down regulation of fumitremorgin B biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of fumitremorgin B biosynthetic process. GO:1900851 positive regulation of pseurotin A biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900851 upregulation of pseurotin A biosynthetic process|up-regulation of pseurotin A biosynthetic process|up regulation of pseurotin A biosynthetic process Any process that activates or increases the frequency, rate or extent of pseurotin A biosynthetic process. GO:1900850 negative regulation of pseurotin A biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900850 down regulation of pseurotin A biosynthetic process|down-regulation of pseurotin A biosynthetic process|downregulation of pseurotin A biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of pseurotin A biosynthetic process. GO:1900853 negative regulation of terrequinone A biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900853 down regulation of terrequinone A biosynthetic process|downregulation of terrequinone A biosynthetic process|down-regulation of terrequinone A biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of terrequinone A biosynthetic process. GO:1900852 regulation of terrequinone A biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900852 regulation of terrequinone A synthesis|regulation of terrequinone A biosynthesis|regulation of terrequinone A formation|regulation of terrequinone A anabolism Any process that modulates the frequency, rate or extent of terrequinone A biosynthetic process. CHEBI:35552 heterocyclic organic fundamental parent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35552 CHEBI:35555 mancude organic heteromonocyclic parent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35555 CHEBI:35554 cardiovascular drug biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35554 CHEBI:35557 3H-pyrrole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35557 CHEBI:35556 pyrrole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35556 GO:0071989 establishment of protein localization to spindle pole body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071989 establishment of protein localisation to spindle pole body The directed movement of a protein to a specific location at the spindle pole body. CHEBI:35559 furan biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35559 GO:0071988 protein localization to spindle pole body biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071988 protein localisation to spindle pole body A process in which a protein is transported to, or maintained at, the spindle pole body. CHEBI:35558 2H-pyrrole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35558 GO:0071987 WD40-repeat domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071987 WD domain binding|beta-transducin repeat domain binding Interacting selectively and non-covalently with a WD40 repeat domain of a protein. The WD40 repeat is a short structural motif of approximately 40 amino acids, often terminating in a tryptophan-aspartic acid (W-D) dipeptide. Several of these repeats are combined to form a type of protein domain called the WD domain. GO:0071986 Ragulator complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0071986 MAPKSP1/ROBLD3/C11orf59 complex A eukaryotically conserved protein complex; in humans, it is comprised of LAMTOR1, LAMTOR2, LAMTOR3, LAMTOR4, and LAMTOR5. The complex is anchored to lipid rafts in late endosome membranes via LAMTOR1, constitutes a guanine nucleotide exchange factor (GEF) for the Rag GTPases. GO:0071985 multivesicular body sorting pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071985 A vesicle-mediated transport process in which transmembrane proteins are ubiquitylated to facilitate their entry into luminal vesicles of multivesicular bodies (MVBs); upon subsequent fusion of MVBs with lysosomes or vacuoles, the cargo proteins are degraded. GO:0071984 maintenance of reproductive diapause biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071984 The dormancy process that results an organism remaining in reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli. GO:0071983 exit from reproductive diapause biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071983 The dormancy process that results in exit from reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli. CHEBI:59524 lipoarabinomannan biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59524 GO:0071982 maintenance of diapause biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071982 The dormancy process that results an organism remaining in diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation. GO:0071981 exit from diapause biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071981 The dormancy process that results in exit from diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation. GO:0071980 cell surface adhesin-mediated gliding motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071980 Cell gliding that results from the actions of cell surface adhesin proteins that are propelled by membrane motor proteins. CHEBI:35550 1H-1,2,4-triazole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35550 GO:1900869 tatiopterin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900869 tatiopterin metabolism The chemical reactions and pathways involving tatiopterin. GO:0007309 oocyte axis specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007309 oocyte axis determination The establishment, maintenance and elaboration of an axis in the oocyte. An example of this is found in Drosophila melanogaster. GO:0007308 oocyte construction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007308 oocyte arrangement The synthesis, deposition, and organization of the materials in a cell of an ovary; where the cell can then undergo meiosis and form an ovum. An example of this is found in Drosophila melanogaster. GO:0007307 eggshell chorion gene amplification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007307 Amplification by up to 60-fold of the loci containing the chorion gene clusters. Amplification is necessary for the rapid synthesis of chorion proteins by the follicle cells, and occurs by repeated firing of one or more origins located within each gene cluster. GO:1900866 glycolate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900866 The directed movement of a glycolate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0007306 eggshell chorion assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007306 eggshell chorion formation|insect chorion formation Construction of the chorion portion of the eggshell, which comprises the channels for gas exchange in an insect eggshell. GO:1900865 chloroplast RNA modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900865 RNA editing in chloroplast Any RNA modification that takes place in chloroplast. GO:0007305 vitelline membrane formation involved in chorion-containing eggshell formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007305 vitelline membrane formation in chorion-containing eggshell Construction of the vitelline membrane portion of a chorion-containing eggshell. An example of this is found in Drosophila melanogaster. GO:0007304 chorion-containing eggshell formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007304 eggshell formation The construction of a chorion-containing eggshell. An example of this is found in Drosophila melanogaster. GO:1900868 sarcinapterin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900868 sarcinapterin formation|sarcinapterin biosynthesis|sarcinapterin anabolism|sarcinapterin synthesis The chemical reactions and pathways resulting in the formation of sarcinapterin. GO:0007303 cytoplasmic transport, nurse cell to oocyte biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007303 The directed movement of cytoplasmic constituents synthesized in the nurse cells to the oocyte. GO:1900867 sarcinapterin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900867 sarcinapterin metabolism The chemical reactions and pathways involving sarcinapterin. GO:1900862 negative regulation of cordyol C biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900862 down regulation of cordyol C biosynthetic process|down-regulation of cordyol C biosynthetic process|downregulation of cordyol C biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of cordyol C biosynthetic process. GO:0007302 nurse cell nucleus anchoring biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007302 Attachment of the nurse cell nucleus to the plasma membrane. GO:0007301 female germline ring canal formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007301 ovarian ring canal formation|nurse cell ring canal formation Assembly of the intercellular bridges that connect the germ-line cells of a female cyst. GO:1900861 regulation of cordyol C biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900861 Any process that modulates the frequency, rate or extent of cordyol C biosynthetic process. GO:0007300 ovarian nurse cell to oocyte transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007300 nurse cell to oocyte transport Transfer of constituents synthesized in the ovarian nurse cells to the oocyte, through the ring canals, as the egg chamber is growing. An example of this is found in Drosophila melanogaster. GO:1900864 mitochondrial RNA modification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900864 mitochondrial RNA editing Any RNA modification that takes place in mitochondrion. GO:1900863 positive regulation of cordyol C biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900863 upregulation of cordyol C biosynthetic process|up-regulation of cordyol C biosynthetic process|activation of cordyol C biosynthetic process|up regulation of cordyol C biosynthetic process Any process that activates or increases the frequency, rate or extent of cordyol C biosynthetic process. GO:1900860 positive regulation of brevianamide F biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900860 up-regulation of brevianamide F biosynthetic process|upregulation of brevianamide F biosynthetic process|up regulation of brevianamide F biosynthetic process Any process that activates or increases the frequency, rate or extent of brevianamide F biosynthetic process. CHEBI:35568 mancude ring biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35568 GO:0071979 cytoskeleton-mediated cell swimming biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071979 cytoskeleton-mediated swimming motility Cell motility in which contractile cytoskeletal elements alter cell shape, resulting in the smooth movement of a cell through a liquid medium. GO:0071978 bacterial-type flagellum-dependent swarming motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071978 bacterial-type flagellar swarming motility|bacterial-type flagellum-mediated cell swarming Bacterial-type flagellum-dependent cell motility in which the action of numerous flagella results in the smooth movement of a group of cells along a solid surface. Swarming motility is observed in groups of bacteria. GO:0071977 bacterial-type flagellum-dependent swimming motility biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071977 bacterial-type flagellum-mediated cell swimming|bacterial-type flagellar swimming motility Bacterial-type flagellum-dependent cell motility that results in the smooth movement of a cell through a liquid medium. CHEBI:35569 alpha-adrenergic agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35569 GO:0071976 cell gliding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071976 cell gliding motility Cell motility that results in the smooth movement of a cell along a solid surface. CHEBI:59517 DNA synthesis inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59517 GO:0071975 cell swimming biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071975 cell swimming motility Cell motility that results in the smooth movement of a cell through a liquid medium. GO:0071974 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0071974 GO:0071973 bacterial-type flagellum-dependent cell motility biolink:BiologicalProcess go-plus goslim_metagenomics http://purl.obolibrary.org/obo/GO_0071973 bacterial-type flagellar cell motility|flagellin-based flagellar cell motility Cell motility due to the motion of one or more bacterial-type flagella. A bacterial-type flagellum is a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope. GO:0071972 peptidoglycan L,D-transpeptidase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071972 MetaCyc:RXN-11349 Catalysis of the reaction: 2 a peptidoglycan dimer (tetrapeptide) + 3 H2O = a peptidoglycan tetramer with L,D cross-links (L-Lys-D-Asn-L-Lys) + di-trans,poly-cis-undecaprenyl diphosphate + 4 D-alanine. CHEBI:35560 1,2,4-triazole biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35560 CHEBI:59513 monodehydro-L-ascorbate(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59513 GO:0071971 extracellular exosome assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071971 extracellular vesicular exosome assembly The aggregation, arrangement and bonding together of a set of components to form an extracellular vesicular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Exosomes are defined by their size, which generally ranges from 30 nm to 100 nm. GO:0071970 fungal-type cell wall (1->3)-beta-D-glucan biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071970 fungal-type cell wall 1,3-beta-glucan formation|fungal-type cell wall 1,3-beta-glucan biosynthesis|fungal-type cell wall beta-1,3-glucan anabolism|fungal-type cell wall 1,3-beta-D-glucan biosynthetic process|fungal-type cell wall beta-1,3-glucan synthesis|fungal-type cell wall beta-1,3-glucan formation|fungal-type cell wall beta-1,3-glucan biosynthetic process|fungal-type cell wall beta-1,3-glucan biosynthesis|fungal-type cell wall 1,3-beta-glucan anabolism|fungal-type cell wall 1,3-beta-glucan synthesis The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in fungal cell walls. CHEBI:35561 3H-1,2,4-triazole biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35561 GO:0032393 MHC class I receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032393 gamma-delta T cell receptor activity|alpha-beta T cell receptor activity|T cell receptor activity Combining with an MHC class I protein complex to initiate a change in cellular activity. Class I here refers to classical class I molecules. GO:0032392 DNA geometric change biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0032392 The process in which a transformation is induced in the geometry of a DNA double helix, resulting in a change in twist, writhe, or both, but with no change in linking number. Includes the unwinding of double-stranded DNA by helicases. GO:0032391 photoreceptor connecting cilium biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032391 photoreceptor cilium The portion of the photoreceptor cell cilium linking the photoreceptor inner and outer segments. It's considered to be equivalent to the ciliary transition zone. GO:0032390 MutLbeta complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032390 MLH1/PMS1 complex|MMR complex A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS1. GO:0032399 HECT domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032399 Interacting selectively and non-covalently with a HECT, 'Homologous to the E6-AP Carboxy-Terminus', domain of a protein. GO:0032398 MHC class Ib protein complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032398 A transmembrane protein complex composed of a MHC class Ib alpha chain and, in most cases, an invariant beta2-microglobin chain, and with or without a bound peptide or lipid antigen. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families. GO:0032397 activating MHC class I receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032397 Combining with a MHC class I protein complex to mediate signaling that activates a lymphocyte. GO:0032396 inhibitory MHC class I receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032396 Combining with a MHC class I protein complex to mediate signaling that inhibits activation of a lymphocyte. GO:0032395 MHC class II receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032395 gamma-delta T cell receptor activity|alpha-beta T cell receptor activity|T cell receptor activity Combining with an MHC class II protein complex and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. GO:0032394 MHC class Ib receptor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032394 gamma-delta T cell receptor activity|alpha-beta T cell receptor activity|T cell receptor activity Combining with an MHC class Ib protein complex and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families. GO:0032382 positive regulation of intracellular sterol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032382 up regulation of intracellular sterol transport|upregulation of intracellular sterol transport|stimulation of intracellular sterol transport|up-regulation of intracellular sterol transport|activation of intracellular sterol transport Any process that activates or increases the frequency, rate or extent of the directed movement of sterols within cells. GO:0032381 negative regulation of intracellular sterol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032381 downregulation of intracellular sterol transport|down regulation of intracellular sterol transport|inhibition of intracellular sterol transport|down-regulation of intracellular sterol transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of sterols within cells. GO:0032380 regulation of intracellular sterol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032380 Any process that modulates the frequency, rate or extent of the directed movement of sterols within cells. GO:0032389 MutLalpha complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032389 MutL-alpha complex|MMR complex|MLH1/PMS2 complex A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS2. GO:0032388 positive regulation of intracellular transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032388 upregulation of intracellular transport|up regulation of intracellular transport|activation of intracellular transport|stimulation of intracellular transport|up-regulation of intracellular transport Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells. GO:0032387 negative regulation of intracellular transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032387 down regulation of intracellular transport|downregulation of intracellular transport|down-regulation of intracellular transport|inhibition of intracellular transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells. GO:0032386 regulation of intracellular transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032386 Any process that modulates the frequency, rate or extent of the directed movement of substances within cells. GO:0032385 positive regulation of intracellular cholesterol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032385 up regulation of intracellular cholesterol transport|activation of intracellular cholesterol transport|stimulation of intracellular cholesterol transport|up-regulation of intracellular cholesterol transport|upregulation of intracellular cholesterol transport Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol within cells. GO:0032384 negative regulation of intracellular cholesterol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032384 down-regulation of intracellular cholesterol transport|inhibition of intracellular cholesterol transport|down regulation of intracellular cholesterol transport|downregulation of intracellular cholesterol transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of cholesterol within cells. GO:0032383 regulation of intracellular cholesterol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032383 Any process that modulates the frequency, rate or extent of the directed movement of cholesterol within cells. GO:0046907 intracellular transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046907 single organism intracellular transport|single-organism intracellular transport The directed movement of substances within a cell. CHEBI:60520 1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60520 GO:0032371 regulation of sterol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032371 Any process that modulates the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0032370 positive regulation of lipid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032370 up-regulation of lipid transport|upregulation of lipid transport|up regulation of lipid transport|activation of lipid transport|stimulation of lipid transport Any process that activates or increases the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0046906 tetrapyrrole binding biolink:MolecularActivity go-plus goslim_pir|goslim_metagenomics http://purl.obolibrary.org/obo/GO_0046906 porphyrin binding Interacting selectively and non-covalently with a tetrapyrrole, a compound containing four pyrrole nuclei variously substituted and linked to each other through carbons at the alpha position. GO:0046905 phytoene synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046905 Catalysis of the reaction: prephytoene pyrophosphate = phytoene + diphosphate. CHEBI:60522 phosphatidylglycerol phosphate(3-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60522 GO:0046904 calcium oxalate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046904 Interacting selectively and non-covalently with calcium oxalate, CaC2O4, a salt of oxalic acid. In animals, it may be excreted in urine or retained in the form of urinary calculi. CHEBI:60521 indole alkaloid cation biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60521 GO:0046903 secretion biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0046903 The controlled release of a substance by a cell or a tissue. CHEBI:60524 3-O-L-alanyl-1-O-phosphatidylglycerol zwitterion biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60524 GO:0046902 regulation of mitochondrial membrane permeability biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046902 regulation of transport across mitochondrial membrane|regulation of mitochondrial envelope permeability Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane. CHEBI:60523 phosphatidylglycerol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60523 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046901 THF polyglutamylation|tetrahydrofolate polyglutamylation|tetrahydrofolyl-[Glu](n) biosynthesis|tetrahydrofolyl-[Glu](n) biosynthetic process|tetrahydrofolylpolyglutamate anabolism|folic acid-containing compound polyglutamylation|tetrahydrofolylpolyglutamate synthesis|tetrahydrofolylpolyglutamate formation|tetrahydrofolylpolyglutamate biosynthesis The chemical reactions and pathways resulting in the formation of tetrahydrofolylpolyglutamate, a folate derivative comprising tetrahydrofolate attached to a chain of glutamate residues. GO:0046900 tetrahydrofolylpolyglutamate metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046900 tetrahydrofolylpolyglutamate metabolism|tetrahydrofolyl-[Glu](n) metabolism|tetrahydrofolyl-[Glu](n) metabolic process The chemical reactions and pathways involving tetrahydrofolylpolyglutamate, a folate derivative comprising tetrahydrofolate attached to a chain of glutamate residues. GO:0032379 positive regulation of intracellular lipid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032379 up-regulation of intracellular lipid transport|upregulation of intracellular lipid transport|up regulation of intracellular lipid transport|activation of intracellular lipid transport|stimulation of intracellular lipid transport Any process that activates or increases the frequency, rate or extent of the directed movement of lipids within cells. GO:0032378 negative regulation of intracellular lipid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032378 inhibition of intracellular lipid transport|down regulation of intracellular lipid transport|downregulation of intracellular lipid transport|down-regulation of intracellular lipid transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids within cells. GO:0032377 regulation of intracellular lipid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032377 Any process that modulates the frequency, rate or extent of the directed movement of lipids within cells. GO:0032376 positive regulation of cholesterol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032376 up-regulation of cholesterol transport|upregulation of cholesterol transport|up regulation of cholesterol transport|activation of cholesterol transport|stimulation of cholesterol transport Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. CHEBI:60529 ergoline alkaloid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60529 GO:0032375 negative regulation of cholesterol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032375 down-regulation of cholesterol transport|inhibition of cholesterol transport|down regulation of cholesterol transport|downregulation of cholesterol transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0032374 regulation of cholesterol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032374 Any process that modulates the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0032373 positive regulation of sterol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032373 activation of sterol transport|up regulation of sterol transport|upregulation of sterol transport|stimulation of sterol transport|up-regulation of sterol transport Any process that activates or increases the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0046909 obsolete intermembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046909 OBSOLETE. The directed movement of substances between any membrane of a cell, including the plasma membrane and its regions. GO:0046908 obsolete negative regulation of crystal formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046908 negative regulation of crystal formation|negative regulation of mineralization OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the spontaneous (nonenzymatic) formation of crystals in a solution, for example, calcium oxalate crystals in urine. GO:0032372 negative regulation of sterol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032372 down-regulation of sterol transport|downregulation of sterol transport|down regulation of sterol transport|inhibition of sterol transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0032369 negative regulation of lipid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032369 down regulation of lipid transport|downregulation of lipid transport|down-regulation of lipid transport|inhibition of lipid transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0046910 pectinesterase inhibitor activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046910 Stops, prevents or reduces the activity of any pectinesterase enzyme. GO:0046918 N-terminal peptidyl-glycine N-palmitoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046918 RESID:AA0339 The covalent attachment of a palmitoyl group to a nitrogen (N) atom in an N-terminal glycine residue to form N-palmitoyl-glycine. GO:0032360 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032360 CHEBI:60531 flavin(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60531 GO:0046917 triphosphoribosyl-dephospho-CoA synthase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046917 MetaCyc:2.7.8.25-RXN|EC:2.4.2.52|RHEA:15117 2'-(5''-triphosphoribosyl)-3-dephospho-CoA synthase activity|CitG activity|ATP:3-dephospho-CoA 5''-triphosphoribosyltransferase activity|ATP:dephospho-CoA 5-triphosphoribosyl transferase activity Catalysis of the reaction: ATP + 3-dephospho-CoA = 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA + adenine. CHEBI:60530 ferroheme o(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60530 GO:0046916 cellular transition metal ion homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046916 Any process involved in the maintenance of an internal steady state of transition metal ions at the level of a cell. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver. GO:0046915 transition metal ion transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046915 Enables the transfer of transition metal ions from one side of a membrane to the other. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver. GO:0046914 transition metal ion binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046914 Interacting selectively and non-covalently with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver. GO:0046913 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046913 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046912 EC:2.3.3.- Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor), with the acyl group being converted into alkyl on transfer. GO:0046911 metal chelating activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046911 metal chelation|heavy metal chelation The formation of bonds from two or more atoms within the same ligand to a metal atom in complexes in which the metal is part of a ring. GO:0032368 regulation of lipid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032368 Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0032367 intracellular cholesterol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032367 The directed movement of cholesterol, cholest-5-en-3-beta-ol, within cells. GO:0032366 intracellular sterol transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032366 The directed movement of sterols within cells. GO:0032365 intracellular lipid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032365 The directed movement of lipids within cells. GO:0032364 oxygen homeostasis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032364 A homeostatic process involved in the maintenance of an internal steady state of oxygen within an organism or cell. GO:0032363 FMN catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032363 The chemical reactions and pathways resulting in the breakdown of FMN, riboflavin 5'-(dihydrogen phosphate), a coenzyme for a number of oxidative enzymes including NADH dehydrogenase. GO:0032362 obsolete FAD catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032362 FAD breakdown|FAD catabolism|oxidized flavin adenine dinucleotide catabolic process|FAD degradation OBSOLETE. The chemical reactions and pathways resulting in the breakdown of FAD, the oxidized form of flavin-adenine dinucleotide. GO:0032361 pyridoxal phosphate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032361 The chemical reactions and pathways resulting in the breakdown of pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6. GO:0046919 pyruvyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046919 Catalysis of the transfer of a pyruvyl (oxopropanoyl) group from one compound to another. CHEBI:84509 2-all-trans-heptaprenylphenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84509 GO:0032359 provirus excision biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032359 prophage excision The molecular events that lead to the excision of a viral genome from the host genome. GO:0032358 oxidized pyrimidine DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032358 oxidized pyrimidine base DNA binding|oxidised pyrimidine DNA binding|oxidized pyrimidine nucleobase DNA binding Interacting selectively and non-covalently with oxidized pyrimidine residues in DNA. GO:0046921 alpha-(1->6)-fucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046921 alpha(1,6)-fucosyltransferase activity|alpha-1,6-fucosyltransferase activity|alpha-(1,6)-fucosyltransferase activity Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->6) linkage. GO:0046920 alpha-(1->3)-fucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046920 Reactome:R-HSA-9605644|Reactome:R-HSA-9605609|Reactome:R-HSA-9605682|Reactome:R-HSA-9603984 alpha(1,3)-fucosyltransferase activity|alpha-(1,3)-fucosyltransferase activity|alpha-1,3-fucosyltransferase activity Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->3) linkage. GO:0007399 nervous system development biolink:BiologicalProcess go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0007399 pan-neural process The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state. GO:0007398 ectoderm development biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007398 The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. In animal embryos, the ectoderm is the outer germ layer of the embryo, formed during gastrulation. CHEBI:84503 4-hydroxy-3-all-trans-decaprenylbenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84503 CHEBI:84502 4-hydroxy-3-all-trans-nonaprenylbenzoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84502 GO:0007397 obsolete histogenesis and organogenesis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007397 histogenesis and organogenesis OBSOLETE. The generation of organized tissues or of whole organs. GO:0007396 suture of dorsal opening biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007396 Closure of the dorsal hole. Filopodia extending from each leading edge interdigitate at the dorsal midline and appear to prime the formation of adherens junctions between the two rows of leading edge cells. Newly formed septate junctions are also used to seal the dorsal hole. CHEBI:84501 4-hydroxy-3-all-trans-nonaprenylbenzoic acid biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84501 GO:0007395 dorsal closure, spreading of leading edge cells biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007395 Dorsally-directed movement of a cell at the leading edge of the epithelium over the amnioserosa. CHEBI:60540 coenzyme F430(5-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60540 GO:0007394 dorsal closure, elongation of leading edge cells biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007394 The change in shape of cells at the dorsal-most (leading) edge of the epidermis from being polygonal to being elongated in the dorsal/ventral axis. GO:0046929 negative regulation of neurotransmitter secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046929 down-regulation of neurotransmitter secretion|downregulation of neurotransmitter secretion|conotoxin activity|down regulation of neurotransmitter secretion|inhibition of neurotransmitter secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter. GO:0046928 regulation of neurotransmitter secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046928 Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell. GO:0046927 peptidyl-threonine racemization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046927 The racemization of peptidyl-L-threo-threonine at the alpha-carbon to form D-allo-threonine. This is coupled with the formation of the cross-link 2-(S-L-cysteinyl)-D-allo-threonine. GO:0046926 peptide cross-linking via 2-(S-L-cysteinyl)-D-allo-threonine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046926 RESID:AA0342 The post-translational cross-linking of a cysteine residue to an L-threonine residue to form 2-(S-L-cysteinyl)-D-allo-threonine. GO:0046925 peptide cross-linking via 2-(S-L-cysteinyl)-D-phenylalanine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046925 RESID:AA0341 The cross-linking of a cysteine residue to an L-phenylalanine residue to form 2-(S-L-cysteinyl)-D-phenylalanine. GO:0046924 peptide cross-linking via 2-(S-L-cysteinyl)-L-phenylalanine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046924 RESID:AA0340 The cross-linking of a cysteine residue to an L-phenylalanine residue to form 2-(S-L-cysteinyl)-L-phenylalanine. OIO:inSubset in_subset biolink:OntologyClass go-plus http://www.geneontology.org/formats/oboInOwl#inSubset GO:0046923 ER retention sequence binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046923 endoplasmic reticulum retention sequence binding Interacting selectively and non-covalently with an endoplasmic reticulum (ER) retention sequence, a specific peptide sequence that ensures a protein is retained within the ER. GO:0046922 peptide-O-fucosyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046922 MetaCyc:2.4.1.221-RXN|EC:2.4.1.221|Reactome:R-HSA-5173192|Reactome:R-HSA-1912349 GDP-fucose protein O-fucosyltransferase activity|GDP-L-fucose:polypeptide fucosyltransferase activity|GDP-fucose:polypeptide fucosyltransferase activity|GDP-beta-L-fucose:polypeptide O-alpha-L-fucosyltransferase activity Catalysis of the transfer of an alpha-L-fucosyl residue from GDP- beta-L-fucose to the serine hydroxy group of a protein acceptor. GO:0032357 oxidized purine DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032357 oxidized purine base DNA binding|oxidized purine nucleobase DNA binding|oxidised purine DNA binding Interacting selectively and non-covalently with oxidized purine residues in DNA. GO:0032356 oxidized DNA binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032356 oxidised DNA binding Interacting selectively and non-covalently with oxidized residues in DNA. CHEBI:60549 ferroheme d1(4-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_60549 GO:0032355 response to estradiol biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032355 response to estradiol stimulus|response to E2 stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen. GO:0032354 response to follicle-stimulating hormone biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032354 response to follicle-stimulating hormone stimulus|response to FSH stimulus|response to follicle stimulating hormone stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus. GO:0032353 negative regulation of hormone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032353 down regulation of hormone biosynthetic process|inhibition of hormone biosynthetic process|down-regulation of hormone biosynthetic process|downregulation of hormone biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones. GO:0032352 positive regulation of hormone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032352 upregulation of hormone metabolic process|up regulation of hormone metabolic process|activation of hormone metabolic process|stimulation of hormone metabolic process|up-regulation of hormone metabolic process|positive regulation of hormone metabolism Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any hormone. GO:0032351 negative regulation of hormone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032351 down regulation of hormone metabolic process|downregulation of hormone metabolic process|down-regulation of hormone metabolic process|negative regulation of hormone metabolism|inhibition of hormone metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any hormone. GO:0032350 regulation of hormone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032350 regulation of hormone metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any hormone. GO:0032349 positive regulation of aldosterone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032349 activation of aldosterone biosynthetic process|up-regulation of aldosterone biosynthetic process|up regulation of aldosterone biosynthetic process|upregulation of aldosterone biosynthetic process|stimulation of aldosterone biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone. GO:0032348 negative regulation of aldosterone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032348 down-regulation of aldosterone biosynthetic process|downregulation of aldosterone biosynthetic process|down regulation of aldosterone biosynthetic process|inhibition of aldosterone biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone. GO:0032347 regulation of aldosterone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032347 Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone. CHEBI:84518 3-(all-trans-decaprenyl)benzene-1,2-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84518 GO:0046932 sodium-transporting ATP synthase activity, rotational mechanism biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046932 RHEA:58158|TC:3.A.2.1.2|EC:7.2.2.1|MetaCyc:3.6.3.15-RXN sodium-translocating F-type ATPase activity|sodium-transporting two-sector ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ADP + phosphate + Na+(out) => ATP + H2O + Na+(in), by a rotational mechanism. CHEBI:84517 3-(all-trans-nonaprenyl)benzene-1,2-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84517 GO:0046931 pore complex assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046931 pore complex biogenesis|pore-forming toxin activity|pore formation|pore biosynthesis The aggregation, arrangement and bonding together of a set of components to form a pore complex. A pore complex is a small opening in a membrane that allows the passage of liquids and/or gases. CHEBI:84516 3-(all-trans-heptaprenyl)benzene-1,2-diol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84516 GO:0046930 pore complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0046930 channel-forming toxin activity|pore|pore-forming toxin activity A protein complex providing a discrete opening in a membrane that allows the passage of gases and/or liquids. CHEBI:84515 sn-glycero-3-phosphoglycerol(1-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84515 PR:000006013 catenin delta-2 biolink:Protein go-plus http://purl.obolibrary.org/obo/PR_000006013 CTNND2|NPRAP|delta-catenin|GT24|neural plakophilin-related ARM-repeat protein|neurojungin|Catnd2 A protein that is a translation product of the human CTNND2 gene or a 1:1 ortholog thereof. CHEBI:84513 1-stearoyl-2-linoleoyl-sn-glycero-3-phospho-L-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_84513 CHEBI:84511 2-all-trans-decaprenylphenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84511 CHEBI:142880 7,2'-dihydroxy-4'-methoxyisoflavanol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_142880 CHEBI:84510 2-all-trans-nonaprenylphenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84510 GO:0046939 nucleotide phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046939 The process of introducing one or more phosphate groups into a nucleotide to produce a phosphorylated nucleoside. GO:0046938 phytochelatin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046938 phytochelatin anabolism|phytochelatin synthesis|phytochelatin formation|phytochelatin biosynthesis|cadystin biosynthetic process The chemical reactions and pathways resulting in the formation of phytochelatins, any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. The structure is of the type (gamma-glutamyl-cysteinyl)n-glycine, where n is 2 to 11. GO:0046937 phytochelatin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046937 cadystin metabolism|phytochelatin metabolism|cadystin metabolic process The chemical reactions and pathways involving phytochelatins, any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. The structure is of the type (gamma-glutamyl-cysteinyl)n-glycine, where n is 2 to 11. GO:0046936 2'-deoxyadenosine deaminase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046936 MetaCyc:ADDALT-RXN|RHEA:28190 deoxyadenosine deaminase reaction Catalysis of the reaction: 2'-deoxyadenosine + H2O = deoxyinosine + NH3. GO:0046935 1-phosphatidylinositol-3-kinase regulator activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046935 1-phosphatidylinositol 3-kinase regulator activity|phosphatidylinositol 3-kinase, class I, regulator activity Modulates the activity of the enzyme 1-phosphatidylinositol-3-kinase activity. GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046934 Reactome:R-HSA-5654697|Reactome:R-HSA-2394007|Reactome:R-HSA-5654709|Reactome:R-HSA-9665407|Reactome:R-HSA-2316434|Reactome:R-HSA-1676048|Reactome:R-HSA-389158|Reactome:R-HSA-177939|Reactome:R-HSA-202365|Reactome:R-HSA-5654692|Reactome:R-HSA-9021627|Reactome:R-HSA-5654717|Reactome:R-HSA-5654705|Reactome:R-HSA-5637801|Reactome:R-HSA-5654714|Reactome:R-HSA-2424480|Reactome:R-HSA-2730870|Reactome:R-HSA-2029271|KEGG_REACTION:R04545|Reactome:R-HSA-5654701|Reactome:R-HSA-1839091|Reactome:R-HSA-5655235|Reactome:R-HSA-198266|MetaCyc:2.7.1.153-RXN|Reactome:R-HSA-1226014|Reactome:R-HSA-5655323|Reactome:R-HSA-9603445|Reactome:R-HSA-5655289|Reactome:R-HSA-5218819|Reactome:R-HSA-1306979|RHEA:21292|EC:2.7.1.153|Reactome:R-HSA-8853323|Reactome:R-HSA-5654690|Reactome:R-HSA-2076220|Reactome:R-HSA-1250462|Reactome:R-HSA-186800|Reactome:R-HSA-392300|Reactome:R-HSA-9664940|Reactome:R-HSA-8852019|Reactome:R-HSA-1306957|Reactome:R-HSA-1839107|Reactome:R-HSA-437162|Reactome:R-HSA-5655290|Reactome:R-HSA-1250370|Reactome:R-HSA-9664664|Reactome:R-HSA-9672177|Reactome:R-HSA-9672162 phosphatidylinositol 3-kinase, class I, catalyst activity|ATP:1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 3-phosphotransferase activity|type I phosphoinositide 3-kinase activity|phosphatidylinositol 3-kinase activity, class I|phosphatidylinositol 3-kinase activity, class II Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + ADP + 2 H(+). GO:0046933 proton-transporting ATP synthase activity, rotational mechanism biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046933 RHEA:57722|EC:7.1.2.2|TC:3.A.2.1.1|Reactome:R-HSA-164832|MetaCyc:ATPSYN-RXN hydrogen ion transporting two-sector ATPase activity|H+-transporting ATP synthase activity|hydrogen ion transporting ATP synthase activity, rotational mechanism|hydrogen ion translocating F-type ATPase activity Enables the synthesis of ATP from ADP and phosphate by the transfer of protons from one side of a membrane to the other by a rotational mechanism driven by a gradient according to the reaction: ADP + H2O + phosphate + H+(in) = ATP + H+(out). GO:0032346 positive regulation of aldosterone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032346 up regulation of aldosterone metabolic process|activation of aldosterone metabolic process|stimulation of aldosterone metabolic process|positive regulation of aldosterone metabolism|up-regulation of aldosterone metabolic process|upregulation of aldosterone metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving aldosterone. GO:0032345 negative regulation of aldosterone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032345 down-regulation of aldosterone metabolic process|negative regulation of aldosterone metabolism|inhibition of aldosterone metabolic process|down regulation of aldosterone metabolic process|downregulation of aldosterone metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving aldosterone. GO:0032344 regulation of aldosterone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032344 regulation of aldosterone metabolism Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving aldosterone. GO:0032343 aldosterone catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032343 The chemical reactions and pathways resulting in the breakdown of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance. GO:0032342 aldosterone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032342 The chemical reactions and pathways resulting in the formation of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance. GO:0032341 aldosterone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032341 aldosterone metabolism The chemical reactions and pathways involving aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance. GO:0032340 positive regulation of inhibin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032340 upregulation of inhibin secretion|up regulation of inhibin secretion|activation of inhibin secretion|stimulation of inhibin secretion|up-regulation of inhibin secretion Any process that activates or increases the frequency, rate or extent of the regulated release of inhibin from a cell. GO:0032339 negative regulation of inhibin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032339 down-regulation of inhibin secretion|inhibition of inhibin secretion|down regulation of inhibin secretion|downregulation of inhibin secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of inhibin from a cell. GO:0032338 regulation of inhibin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032338 Any process that modulates the frequency, rate or extent of the regulated release of inhibin from a cell. GO:0032337 positive regulation of activin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032337 stimulation of activin secretion|up-regulation of activin secretion|upregulation of activin secretion|up regulation of activin secretion|activation of activin secretion Any process that activates or increases the frequency, rate or extent of the regulated release of activin from a cell. GO:0032336 negative regulation of activin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032336 down-regulation of activin secretion|inhibition of activin secretion|down regulation of activin secretion|downregulation of activin secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of activin from a cell. CHEBI:84529 2-methoxy-6-all-trans-nonaprenylhydroquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84529 GO:0046943 carboxylic acid transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046943 Reactome:R-HSA-390347 Enables the transfer of carboxylic acids from one side of a membrane to the other. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-). GO:0007379 segment specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007379 The process in which segments assume individual identities; exemplified in insects by the actions of the products of the homeotic genes. CHEBI:84528 2-methoxy-6-all-trans-heptaprenylhydroquinonel biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84528 GO:0007378 amnioserosa formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007378 Formation of the amnioserosa, an epithelium that occupies a hole in the embryonic dorsal epidermis. This occurs by the transformation of a narrow strip of cells at the dorsal midline of the blastoderm from columnar to squamous cells, accompanied by a lateral shift. GO:0046942 carboxylic acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046942 The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-). GO:0007377 germ-band extension biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007377 Elongation of the germ band on the ventral side of the embryo, accompanied by a halving in width. The elongation process pushes the posterior midgut invagination closed and compresses the amnioserosa further. GO:0046941 azetidine-2-carboxylic acid acetyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0046941 Catalysis of the reaction: L-azetidine-2-carboxylic acid + acetyl-CoA = CoA-SH + N-acetyl azetidine-2-carboxylic acid. GO:0007376 cephalic furrow formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007376 Formation of a partial necklace of inturning tissue on the lateral sides of the embryo, along the dorsal-ventral axis. This furrow demarcates head from thorax in the developing protostome. GO:0046940 nucleoside monophosphate phosphorylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046940 The process of introducing one or more phosphate groups into a nucleoside monophosphate to produce a polyphosphorylated nucleoside. GO:0007375 anterior midgut invagination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007375 Internalization of the anterior midgut into the interior of the embryo. GO:0007374 posterior midgut invagination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007374 Formation of a cup-shaped invagination at the posterior end of the embryo, bringing the posterior midgut and hindgut primordia into the interior. CHEBI:84522 2-methoxy-6-(all-trans-nonaprenyl)phenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84522 GO:0007373 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007373 CHEBI:60562 ferroheme c biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60562 CHEBI:84521 2-methoxy-6-(all-trans-heptaprenyl)phenol biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84521 GO:0007372 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0007372 GO:0071907 determination of digestive tract left/right asymmetry biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071907 determination of gut left/right asymmetry|determination of left/right asymmetry of the digestive tract Determination of the asymmetric location of various parts of the digestive tract with respect to the left and right halves of the organism. The digestive tract is the anatomical structure through which food passes and is processed. GO:0007382 specification of segmental identity, maxillary segment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007382 The specification of the characteristic structures of the maxillary segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized. GO:0071906 CRD domain binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071906 context dependent regulatory domain binding Interacting selectively and non-covalently with a CRD (context dependent regulatory) domain, a domain of about 130 residues that is the most divergent region among the LEF/TCF proteins. GO:0007381 specification of segmental identity, labial segment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007381 The specification of the characteristic structures of the labial segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized. GO:0071905 protein N-linked glucosylation via asparagine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071905 RESID:AA0421 protein amino acid N-linked glucosylation via asparagine A process of protein N-linked glycosylation via asparagine in which glucose is added to the N4 of asparagine, forming an (S)-2-amino-4-(D-glucopyranosyl)amino-4-oxobutanoic acid residue. GO:0007380 specification of segmental identity, head biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007380 The specification of the characteristic structures of the head segments following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized. GO:0046949 fatty-acyl-CoA biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046949 fatty-acyl-CoA anabolism|fatty acyl CoA biosynthetic process|fatty-acyl-CoA biosynthesis|fatty-acyl-CoA synthesis|fatty-acyl-CoA formation The chemical reactions and pathways resulting in the formation of a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group. GO:0071904 protein N-linked N-acetylgalactosaminylation via asparagine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071904 RESID:AA0420 protein amino acid N-linked N-acetylgalactosaminylation via asparagine A process of protein N-linked glycosylation via asparagine in which N-acetylgalactosamine is added to the N4 of asparagine, forming an (S)-2-amino-4-(2-acetamido-2-deoxy-beta-D-galactopyranosyl)amino-4-oxobutanoic acid residue. GO:0046948 hydroxylysine catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046948 hydroxylysine catabolism|hydroxylysine degradation|hydroxylysine breakdown The chemical reactions and pathways resulting in the breakdown of hydroxylysine (5-hydroxy-2,6-diaminohexanoic acid), a chiral alpha-amino acid. GO:0071903 protein N-linked N-acetylglucosaminylation via asparagine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071903 RESID:AA0151 protein amino acid N-linked N-acetylglucosaminylation via asparagine A process of protein N-linked glycosylation via asparagine in which N-acetylglucosamine is added to the N4 of asparagine, forming an (S)-2-amino-4-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)amino-4-oxobutanoic acid residue. CHEBI:60568 1,2-dioleoyl-sn-glycero-3-phospho-L-serine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60568 GO:0046947 hydroxylysine biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046947 hydroxylysine anabolism|hydroxylysine biosynthesis|hydroxylysine synthesis|hydroxylysine formation The chemical reactions and pathways resulting in the formation of hydroxylysine (5-hydroxy-2,6-diaminohexanoic acid), a chiral alpha-amino acid. GO:0071902 positive regulation of protein serine/threonine kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071902 Any process that increases the rate, frequency, or extent of protein serine/threonine kinase activity. GO:0046946 hydroxylysine metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046946 hydroxylysine metabolism The chemical reactions and pathways involving hydroxylysine (5-hydroxy-2,6-diaminohexanoic acid), a chiral alpha-amino acid. Hydroxylysine is found in collagen and commonly has galactose and then glucose added sequentially by glycosyltransferases. GO:0071901 negative regulation of protein serine/threonine kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071901 Any process that decreases the rate, frequency, or extent of protein serine/threonine kinase activity. GO:0046945 N-terminal peptidyl-alanine N-carbamoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046945 RESID:AA0343 N-terminal peptidyl-alanine N-carbamylation The carbamylation of the N-terminal alanine of proteins to form the derivative N-carbamoyl-L-alanine. GO:0071900 regulation of protein serine/threonine kinase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071900 Any process that modulates the rate, frequency, or extent of protein serine/threonine kinase activity. GO:0046944 protein carbamoylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046944 protein amino acid carbamoylation The addition of a carbamoyl group to a protein amino acid. A carbamoyl group is the acyl group -CO-NH2. GO:0032335 regulation of activin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032335 Any process that modulates the frequency, rate or extent of the regulated release of activin from a cell. GO:0032334 inhibin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032334 The regulated release of an inhibin, either of two glycoproteins (designated A and B), secreted by the gonads and present in seminal plasma and follicular fluid, that inhibit pituitary production of follicle-stimulating hormone. GO:0032333 activin secretion biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032333 The regulated release of activin, a nonsteroidal regulator composed of two covalently linked beta subunits, which is synthesized in the pituitary gland and gonads and stimulates the secretion of follicle-stimulating hormone. GO:0032332 positive regulation of chondrocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032332 upregulation of chondrocyte differentiation|up regulation of chondrocyte differentiation|activation of chondrocyte differentiation|stimulation of chondrocyte differentiation|up-regulation of chondrocyte differentiation Any process that activates or increases the frequency, rate or extent of chondrocyte differentiation. GO:0032331 negative regulation of chondrocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032331 down regulation of chondrocyte differentiation|downregulation of chondrocyte differentiation|down-regulation of chondrocyte differentiation|inhibition of chondrocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of chondrocyte differentiation. GO:0032330 regulation of chondrocyte differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032330 Any process that modulates the frequency, rate or extent of chondrocyte differentiation. GO:0032329 serine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032329 serine import The directed movement of L-serine, 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0032328 alanine transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032328 The directed movement of alanine, 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:0032327 W-molybdopterin cofactor catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032327 W-molybdopterin cofactor catabolism|W-molybdopterin cofactor degradation|Moco catabolic process|W-molybdopterin cofactor breakdown|Moco catabolism The chemical reactions and pathways resulting in the breakdown of the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands. GO:0032326 Mo-molybdopterin cofactor catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032326 Mo-molybdopterin cofactor breakdown|Moco catabolic process|Mo-molybdopterin cofactor catabolism|Mo-molybdopterin cofactor degradation|Moco catabolism The chemical reactions and pathways resulting in the breakdown of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands. GO:0032325 molybdopterin cofactor catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032325 The chemical reactions and pathways resulting in the breakdown of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands. GO:0046954 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046954 CHEBI:84539 2-demethylmenaquinol-6 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84539 GO:0007389 pattern specification process biolink:BiologicalProcess go-plus goslim_drosophila http://purl.obolibrary.org/obo/GO_0007389 pattern formation|pattern biosynthesis Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate. GO:0046953 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046953 GO:0046952 ketone body catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046952 MetaCyc:PWY66-368|Reactome:R-HSA-77108 utilization of ketone bodies|ketolysis|ketone body degradation|ketone body breakdown|ketone body catabolism The chemical reactions and pathways resulting in the breakdown of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Ketone bodies can be used as an energy source as an alternative to glucose. Utilization of ketone bodies in peripheral tissues involves conversion of acetoacetate to acetoacetyl-CoA, which is then converted to two molecules of acetyl-CoA. CHEBI:142862 andrastin B biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_142862 GO:0007388 posterior compartment specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007388 The process involved in the specification of cell identity in the posterior compartments of the segmented embryo. CHEBI:84537 dTDP-4-dehydro-2,6-dideoxy-alpha-D-glucose(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84537 GO:0046951 ketone body biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046951 ketone body anabolism|ketone body synthesis|ketone body formation|ketone body biosynthesis The chemical reactions and pathways resulting in the formation of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Biosynthesis involves the formation of hydroxymethylglutaryl-CoA, which is cleaved to acetate and acetyl-CoA. GO:0007387 anterior compartment pattern formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007387 anterior compartment pattern specification The process giving rise to specification of cell identity in the anterior compartments of the segmented embryo. CHEBI:84536 menaquinol-6 biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84536 GO:0007386 compartment pattern specification biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007386 compartment specification The regionalization process in which embryonic segments are divided into compartments that will result in differences in cell differentiation. GO:0046950 cellular ketone body metabolic process biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0046950 cellular ketone body metabolism The chemical reactions and pathways involving ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone, as carried out by individual cells. Although 3-hydroxybutyrate is not a ketone, it is classed as a ketone body because it exists in an equilibrium with acetoacetate. Ketone bodies may accumulate in excessive amounts in the body in starvation, diabetes mellitus or in other defects of carbohydrate metabolism. GO:0007385 specification of segmental identity, abdomen biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007385 The specification of the characteristic structures of the abdominal segments following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized. GO:0007384 specification of segmental identity, thorax biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007384 The specification of the characteristic structures of the thoracic segments following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized. GO:0007383 specification of segmental identity, antennal segment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007383 The specification of the characteristic structures of the antennal segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized. GO:0007393 dorsal closure, leading edge cell fate determination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007393 The cell fate determination process in which a cell within the dorsal ectoderm becomes capable of differentiating autonomously into a leading edge cell regardless of its environment; upon determination, the cell fate cannot be reversed. CHEBI:84531 2-methoxy-3-methyl-6-all-trans-nonaprenylhydroquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84531 CHEBI:60575 phenoxy herbicide biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60575 GO:0007392 initiation of dorsal closure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007392 Events that occur at the start of dorsal closure. CHEBI:84530 6-methoxy-3-methyl-2-all-trans-heptaprenylhydroquinone biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_84530 GO:0007391 dorsal closure biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007391 The process during Drosophila embryogenesis whereby the ectodermal cells of the lateral epithelium stretch in a coordinated fashion to internalize the amnioserosa cells and close the embryo dorsally. CHEBI:59595 arabinofuranosyl group biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_59595 GO:0046959 habituation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046959 Wikipedia:Habituation A decrease in a behavioral response to a repeated stimulus. This is exemplified by the failure of a person to show a startle response to a loud noise that has been repeatedly presented. GO:0007390 germ-band shortening biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0007390 germ-band retraction The spreading of the amnioserosa from its compressed state to cover the whole of the dorsal surface. Initiating in the thorax and spreading posteriorly, it is accompanied by the transition from a parasegmental to segmental division of the embryo. GO:0046958 nonassociative learning biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046958 unconditional response A simple form of learning whereby the repeated presence of a stimulus leads to a change in the probability or strength of the response to that stimulus. There is no association of one type of stimulus with another, rather it is a generalized response to the environment. CHEBI:60579 calcium oxalate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_60579 GO:0046957 negative phototaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046957 negative phototactic behavior|negative taxis in response to light|negative phototactic behaviour The directed movement of a cell or organism away from a source of light. CHEBI:142867 andrastin C biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_142867 GO:0046956 positive phototaxis biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0046956 positive phototactic behavior|positive taxis in response to light|positive phototactic behaviour The directed movement of a cell or organism towards a source of light. GO:0046955 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0046955 GO:0032324 molybdopterin cofactor biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032324 MetaCyc:Molybdenum-Cofactor-Biosynthesis molybdopterin cofactor biosynthesis|molybdopterin cofactor anabolism|molybdopterin cofactor synthesis|molybdopterin cofactor formation The chemical reactions and pathways resulting in the formation of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands. GO:0032323 lipoate catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032323 lipoic acid degradation|lipoic acid breakdown|lipoic acid catabolism The chemical reactions and pathways resulting in the breakdown of lipoate. GO:0032322 ubiquinone catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032322 ubiquinone catabolism|ubiquinone degradation|ubiquinone breakdown The chemical reactions and pathways resulting in the breakdown of ubiquinone, a lipid-soluble electron-transporting coenzyme. GO:0032321 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032321 GO:0032320 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0032320 UBERON:0002195 trabecula of lymph node biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002195 lymph node trabecula|lymph node trabeculum Membranous process coming from capsule of lymph node[WP]. UBERON:0002194 capsule of lymph node biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002194 capsula nodi lymphoidei|lymph node capsule Capsule surrounding lymph node composed of connective tissue with some plain muscle fibers. UBERON:0002196 adenohypophysis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002196 anterior lobe of pituitary gland|AHP|anterior pituitary|anterior lobe of the pituitary|lobus anterior (glandula pituitaria)|lobus anterior|pituitary glandanterior lobe|anterior hypophysis|lobus anterior hypophysis|pituitary anterior lobe|anterior lobe of pituitary|cranial lobe|anterior pituitary gland|anterior lobe (hypophysis)|pituitary gland, anterior lobe|anterior lobe of hypophysis|rostral lobe The glandular, anterior lobe of the pituitary gland. The anterior pituitary regulates several physiological processes including stress, growth, and reproduction[WP]. The anterior lobe of the hypophysis (pituitary gland). This lobe contains cells that produce prolactin, growth hormone, thyroid-stimulating hormone, follicle-stimulating hormone and proopiomelanocortin[ZFA]. UBERON:0002191 subiculum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002191 gyrus parahippocampalis|subiculum cornu ammonis|subiculum hippocampi|subicular cortex Part of the hippocampal formation that is bounded by the entorhinal cortex and area CA1. It is characterized on the CA1 border by an abrupt widening of the pyramidal cell layer. A molecular layer is present that is continuous with that of CA1, although the stratum radiatum is no longer present. The stratum oriens is also not present. adapted from Paxinos, G. The rat central nervous system, 2nd ed, Academic Press, San Diego, 1995, pg. 468) UBERON:0002190 subcutaneous adipose tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002190 panniculus adiposus (tela subcutanea)|fatty layer of subcutaneous tissue|subcutaneous fat|fatty layer of superficial fascia|panniculus adiposus telae subcutaneae|panniculus adiposus|subcutaneous fat layer|hypodermis fat layer A portion of adipose tissue that is part of the hypodermis, beneath the dermis. UBERON:0002193 hemolymphoid system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002193 hematolymphoid system|lymphomyeloid complex|haemolymphoid system Anatomical cluster consisting of the hematopoietic system and the lymphoid system, or its analogs. UBERON:0002199 integument biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002199 dermoid system|integumentum commune|skin|skin plus hypodermis|tegument|Hautsystem@de|dermis plus epidermis plus hypodermis|the integument|vertebrate integument|dermal system|skin and subcutaneous tissue The dermis, epidermis and hypodermis. UBERON:0002198 neurohypophysis biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002198 lobus nervosus|infundibular process|pituitary gland, neural lobe|lobus posterior|posterior lobe of hypophysis|pituitary gland neural lobe|lobus posterior (glandula pituitaria)|posterior lobe of pituitary|neural lobe of pituitary|neuro hypophysis|pituitary gland, posterior lobe|lobus posterior hypophysis|posterior pituitary gland|NHP|lobus nervosus neurohypophysis|neural lobe|neurohypophysis|posterior lobe of pituitary gland|neural lobe of pituitary gland|posterior pituitary The posterior part of the pituitary gland that secretes hormones involved in blood pressure regulation such as oxytocin and antidiuretic hormon. PATO:0000947 elliptic biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/PATO_0000947 ellipsoid|ovoid|ellipse-shaped|oval|elliptical A spheroid quality inhering in a bearer by virtue of the bearer's being oval with two axes of symmetry, as produced by a conical section. GO:0140007 KICSTOR complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140007 A protein complex that regulates the TORC1 signaling pathway in response to nutrients. The KICSTOR complex is composed of KPTN, ITFG2, C12orf66 and SZT2. GO:0140009 L-aspartate import across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140009 The directed movement of L-aspartate from outside of a cell, across the plasma membrane and into the cytosol. UBERON:0002184 segmental bronchus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002184 tertiary bronchus The tertiary bronchi (also known as the segmental bronchi) arise from the secondary bronchi. The respiratory epithelium lining their lumen is surrounded by a layer of smooth muscle. This layer is composed of two ribbons of smooth muscle that spiral in opposite directions. The smooth muscle layer is surrounded by irregular plates of hyaline cartilage which help maintain the patency of the airway. Each of the tertiary bronchi serves a specific bronchopulmonary segment. There are 10 tertiary bronchi in the right lung, and eight in the left. The tertiary bronchi get smaller and divide into primary bronchioles. [WP,unvetted]. UBERON:0002183 lobar bronchus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002183 bronchi lobaris|secondary bronchi|lobar bronchi|secondary bronchus The lobar bronchus is the major airway within the respiratory tree that starts by division of the principal bronchi on both sides and ends at the point of its own subdivision into tertiary or segmental bronchi[GO]. UBERON:0002186 bronchiole biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002186 lobular bronchiole|bronchiolus|bronchioli the conducting airway of the lungs found terminal to the bronchi; these structures contain neither cartilage nor mucous-secreting glands; the epithelium of the bronchioles becomes thinner with each branching UBERON:0002185 bronchus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002185 bronchial tissue|bronchi|bronchial trunk the upper conducting airways of the lung; these airways arise from the terminus of the trachea CHEBI:11502 2-acylglycerophosphocholine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_11502 UBERON:0002187 terminal bronchiole biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002187 bronchioli terminalis|terminal bronchiole tube|bronchiolus terminalis the last conducting structure of non-respiratory bronchioles; after this point, the airways have alveoli in their walls NCBITaxon:32351 melanogaster subgroup organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_32351 GO:0032294 peripheral nervous system non-myelinated axon ensheathment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032294 ensheathment of non-myelinated axons in peripheral nervous system The process in which a non-myelinating Schwann cell membrane encircles an axon in the peripheral nervous system. A single non-myelinating Schwann cell will typically associate with multiple axons. GO:0032293 non-myelinated axon ensheathment in central nervous system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032293 ensheathment of non-myelinated axons in central nervous system The process in which a non-myelinating glial cell membrane encircles an axon in the central nervous system. GO:0032292 peripheral nervous system axon ensheathment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032292 ensheathment of axons in peripheral nervous system The process in which a Schwann cell membrane closes around an axon in the peripheral nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction. GO:0032291 axon ensheathment in central nervous system biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032291 ensheathment of axons in central nervous system The process in which a glial cell membrane closes around an axon in the central nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction. GO:0032290 peripheral nervous system myelin formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032290 myelin formation in peripheral nervous system The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by Schwann cells in the peripheral nervous system. NCBITaxon:32346 melanogaster group organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_32346 GO:0032299 ribonuclease H2 complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032299 RNase H2 complex A protein complex that possesses ribonuclease H activity, in which the catalytic subunit is a member of the RNase H2 (or HII) class. For example, in Saccharomyces the complex contains Rnh201p, Rnh202p and Rnh203p. GO:0032298 positive regulation of DNA-dependent DNA replication initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032298 stimulation of DNA replication initiation|activation of DNA replication initiation|up-regulation of DNA replication initiation|negative regulation of DNA replication initiation|up regulation of DNA replication initiation|upregulation of DNA replication initiation Any process that activates or increases the frequency, rate or extent of initiation of DNA-dependent DNA replication. GO:0032297 negative regulation of DNA-dependent DNA replication initiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032297 negative regulation of DNA replication initiation|down-regulation of DNA replication initiation|downregulation of DNA replication initiation|down regulation of DNA replication initiation|inhibition of DNA replication initiation Any process that stops, prevents, or reduces the frequency, rate or extent of initiation of DNA-dependent DNA replication. NCBITaxon:32341 Sophophora organism taxon go-plus http://purl.obolibrary.org/obo/NCBITaxon_32341 GO:0032296 double-stranded RNA-specific ribonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0032296 double-stranded RNA-specific RNase activity|dsRNA-specific ribonuclease activity|dsRNA-specific RNase activity Catalysis of the hydrolysis of phosphodiester bonds in double-stranded RNA molecules. GO:0032295 ensheathment of neuronal cell bodies biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032295 The process in which satellite glial cells isolate neuronal cell bodies. GO:0032283 plastid acetate CoA-transferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032283 An acetate CoA-transferase complex located in the stroma of a plastid. GO:0032282 plastid acetyl-CoA carboxylase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032282 plastid ACCase complex An acetyl-CoA carboxylase complex located in the stroma of a plastid. GO:0032281 AMPA glutamate receptor complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032281 alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|AMPA-selective glutamate receptor complex|AMPA receptor An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. The AMPA receptors mediate fast synaptic transmission in the CNS and are composed of subunits GluR1-4, products from separate genes. These subunits have an extracellular N-terminus and an intracellular C-terminus. GO:0032280 symmetric synapse biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032280 Gray's type II synapse A synapse that lacks an electron dense postsynaptic specialization. In vertebtrates, these occur primarily on dendrite shafts and neuronal cell bodies and involve persynapses containing clusters of predominantly flattened or elongated vesicles and are typcially inhibitory. GO:0032289 central nervous system myelin formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032289 myelin formation in central nervous system The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the central nervous system. GO:0032288 myelin assembly biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032288 myelin formation The process in which the wraps of cell membrane that constitute myelin are laid down around an axon in the central or peripheral nervous system. GO:0032287 peripheral nervous system myelin maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032287 myelin maintenance in peripheral nervous system The process in which the structure and material content of mature peripheral nervous system myelin is kept in a functional state. GO:0032286 central nervous system myelin maintenance biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032286 myelin maintenance in central nervous system The process in which the structure and material content of mature central nervous system myelin is kept in a functional state. GO:0032285 non-myelinated axon ensheathment biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0032285 ensheathment of non-myelinated axons The process in which a non-myelinating glial cell membrane closes around an axon. GO:0032284 plastid biotin carboxylase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0032284 A biotin carboxylase complex located in the stroma of a plastid. GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071880 activation of adenylate cyclase activity by adrenergic receptor signaling pathway|adrenergic receptor, adenylate cyclase activating pathway|adrenergic receptor, adenylyl cyclase activating pathway|activation of adenylate cyclase activity by adrenergic receptor signalling pathway The series of molecular signals generated as a consequence of an adrenergic receptor binding to its physiological ligand, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP). GO:1900759 positive regulation of D-amino-acid oxidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900759 up-regulation of new yellow enzyme|activation of D-amino-acid:oxygen oxidoreductase (deaminating)|up regulation of L-amino acid:O2 oxidoreductase activity|positive regulation of L-amino acid:O2 oxidoreductase activity|upregulation of D-amino-acid oxidase activity|positive regulation of D-amino-acid:oxygen oxidoreductase (deaminating)|activation of L-amino acid:O2 oxidoreductase activity|up regulation of D-amino-acid:oxygen oxidoreductase (deaminating)|upregulation of new yellow enzyme|up-regulation of L-amino acid:O2 oxidoreductase activity|up regulation of D-amino-acid oxidase activity|activation of D-amino-acid oxidase activity|upregulation of D-amino-acid:oxygen oxidoreductase (deaminating)|up regulation of new yellow enzyme|positive regulation of new yellow enzyme|upregulation of L-amino acid:O2 oxidoreductase activity|activation of new yellow enzyme|up-regulation of D-amino-acid:oxygen oxidoreductase (deaminating)|up-regulation of D-amino-acid oxidase activity Any process that activates or increases the frequency, rate or extent of D-amino-acid oxidase activity. GO:1900756 protein processing in phagocytic vesicle biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900756 peptidolysis during protein maturation in phagocytic vesicle|peptidolysis during protein maturation in phagosome|protein processing in phagosome|protein maturation by peptide bond hydrolysis in phagosome|protein maturation by peptide bond cleavage in phagocytic vesicle|protein maturation by proteolysis in phagocytic vesicle|protein maturation by peptide bond cleavage in phagosome|protein maturation by peptide bond hydrolysis in phagocytic vesicle|protein maturation by proteolysis in phagosome Protein processing that takes place in the phagosome. Most protein processing in the phagosome represents protein degradation. UBERON:0002119 left ovary biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002119 An ovary that is part of a left side of organism [Automatically generated definition]. GO:1900755 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_1900755 UBERON:0002118 right ovary biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002118 An ovary that is part of a right side of organism [Automatically generated definition]. GO:1900758 negative regulation of D-amino-acid oxidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900758 negative regulation of D-amino-acid:oxygen oxidoreductase (deaminating)|down-regulation of D-amino-acid:oxygen oxidoreductase (deaminating)|inhibition of new yellow enzyme|negative regulation of L-amino acid:O2 oxidoreductase activity|down-regulation of L-amino acid:O2 oxidoreductase activity|down regulation of D-amino-acid oxidase activity|downregulation of D-amino-acid:oxygen oxidoreductase (deaminating)|down regulation of new yellow enzyme|downregulation of D-amino-acid oxidase activity|down regulation of D-amino-acid:oxygen oxidoreductase (deaminating)|downregulation of new yellow enzyme|inhibition of L-amino acid:O2 oxidoreductase activity|down-regulation of D-amino-acid oxidase activity|inhibition of D-amino-acid:oxygen oxidoreductase (deaminating)|down-regulation of new yellow enzyme|negative regulation of new yellow enzyme|down regulation of L-amino acid:O2 oxidoreductase activity|inhibition of D-amino-acid oxidase activity|downregulation of L-amino acid:O2 oxidoreductase activity Any process that stops, prevents or reduces the frequency, rate or extent of D-amino-acid oxidase activity. GO:1900757 regulation of D-amino-acid oxidase activity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900757 regulation of D-amino-acid:oxygen oxidoreductase (deaminating)|regulation of new yellow enzyme|regulation of L-amino acid:O2 oxidoreductase activity Any process that modulates the frequency, rate or extent of D-amino-acid oxidase activity. GO:1900752 malonic acid transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900752 HOOC-CH2-COOH transport|propanedioic acid transport|H2malo transport|C3H4O4 transport The directed movement of a malonic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:1900751 4-(trimethylammonio)butanoate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900751 butyrobetaine transport|gamma-butyrobetaine transport|C7H15NO2 transport|gamma-Butyrobetain transport|deoxycarnitine transport|Actinine transport|4-butyrobetaine transport|4-(N-trimethylamino)butyrate transport The directed movement of a 4-(trimethylammonio)butanoate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:1900754 4-hydroxyphenylacetate transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900754 4-hydroxybenzeneacetate transport|2-(4-hydroxyphenyl)ethanoate transport|(4-hydroxyphenyl)acetate transport|(p-hydroxyphenyl)acetate transport The directed movement of a 4-hydroxyphenylacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:1900753 doxorubicin transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900753 14-hydroxydaunorubicine transport|Adriamycin transport|(8S-cis)-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione transport|doxorubicinum transport|(1S,3S)-3-glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside transport|(1S,3S)-3,5,12-trihydroxy-3-(hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside transport|14-hydroxydaunomycin transport|doxorubicine transport The directed movement of a doxorubicin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GO:1900750 oligopeptide binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_1900750 oligopeptides binding|Oligopeptid binding|oligopeptido binding Interacting selectively and non-covalently with an oligopeptide. GO:0140062 5-formylcytosine dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140062 5fC dioxygenase Catalysis of the reaction: 5-formylcytosine+ 2-oxoglutarate + O2 = 5-carboxylcytosine + succinate + CO2. CHEBI:35530 beta-adrenergic antagonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35530 CHEBI:11563 2-deoxy-alpha-D-ribose 1-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_11563 GO:0140065 peptide butyryltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140065 protein butyryltransferase activity Catalysis of the reaction: butyryl-CoA + lysine in peptide = CoA + N-butyryl-lysine-peptide. UBERON:0002120 pronephros biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002120 pronephron|pronephric kidney|archinephron|embryonic kidney In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensible for larval life[GO]. GO:0140064 peptide crotonyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140064 protein crotonyltransferase activity Catalysis of the reaction: crotonyl-CoA + lysine in peptide = CoA + N-crotonyl-lysine-peptide. CHEBI:11561 2-dehydropantoate biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_11561 GO:0140067 peptidyl-lysine butyrylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140067 The butyrylation of a lysine residue in a protein. Butyryl is the univalent radical C3H7COO- derived from butyric acid. CHEBI:3789 cobalt-precorrin-6B biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_3789 GO:0140066 peptidyl-lysine crotonylation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140066 The crotonylation of a lysine residue in a protein. Crotonyl is the univalent radical CH3-CH=CH-CO- derived from crotonic acid. GO:0140069 histone butyryltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140069 Catalysis of the reaction: butyryl-CoA + histone = CoA + butyryl-histone. GO:0140068 histone crotonyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140068 Catalysis of the reaction: crotonyl-CoA + histone = CoA + crotonyl-histone. GO:0071889 14-3-3 protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071889 Interacting selectively and non-covalently with a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided into three sections: a divergent amino terminus, the conserved core region and a divergent carboxy-terminus. The conserved middle core region of the 14-3-3s encodes an amphipathic groove that forms the main functional domain, a cradle for interacting with client proteins. GO:0071888 macrophage apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071888 activation-induced cell death|AICD|macrophage apoptosis Any apoptotic process in a macrophage, a mononuclear phagocyte present in a variety of tissues. UBERON:0002126 solitary tract nuclear complex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002126 nucleus tractus solitarii|solitary nuclei|nuclei of solitary tract The solitary tract and nucleus are structures in the brainstem that carry and receive visceral sensation and taste from the facial (VII), glossopharyngeal (IX) and vagus (X) cranial nerves. [WP,unvetted]. CHEBI:59505 2-hydroxy-5-(methylsulfanyl)-3-oxopent-1-enyl phosphate(2-) biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_59505 GO:0071887 leukocyte apoptotic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071887 leukocyte apoptosis Any apoptotic process in a leukocyte, an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue. UBERON:0002125 thymus lobule biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002125 thymic lobule|thymus lobule|lobule of thymus A lobule that is part of a thymus. Divided into an outer cortex and inner medulla and separated from each other by connective tissue septa, but with the medullary tissue continuous from lobule to lobule.[ncit,modified]. UBERON:0002128 superior olivary complex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002128 superior olivary nucleus|regio olivaris superioris|superior olive|superior olivary nucleus (Barr & Kiernan)|superior olivary nuclei|nucleus olivaris superior A a collection of brainstem nuclei that functions in multiple aspects of hearing and is an important component of the ascending and descending auditory pathways of the auditory system. GO:0071886 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071886 4-iodo-2,5-dimethoxyphenylisopropylamine binding|1-(4-iodo-2,5-dimethoxyphenyl)-2-aminopropane binding|(+/-)2-(4-iodo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine binding Interacting selectively and non-covalently with the amine 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine, a serotonin receptor agonist that can act as a psychedelic drug. UBERON:0002127 inferior olivary complex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002127 caudal olivary nuclei|inferior olive|oliva|inferior olivary nuclei|inferior olivary nuclear complex|nuclei olivares inferiores|inferior olivary complex (Vieussens)|regio olivaris inferior|nuclei olivares caudales|nucleus olivaris caudalis|inferior olivary nucleus|nucleus olivaris inferior|complexus olivaris inferior|complexus olivaris inferior; nuclei olivares inferiores largest nucleus situated in the olivary body, part of the medulla oblongata. It is closely associated with the cerebellum, but its specific function is voluntary body movements. GO:0071885 N-terminal protein N-methyltransferase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071885 X-Pro-Lys N-terminal methyltransferase Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to the alpha-amino group of the N-terminal amino or imino acid residue of a protein substrate. For example, yeast Tae1p and mammalian family member METTL11A preferentially modify the N-terminal residue of substrates with the N-terminal sequence X-Pro-Lys, where X can be Pro, Ala, or Ser. UBERON:0002122 capsule of thymus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002122 thymus capsule|thymic capsule The fibrous connective tissue surrounding the thymus. GO:0071884 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0071884 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071883 activation of MAP kinase activity by adrenergic receptor signalling pathway|activation of MAPK activity by adrenergic receptor signalling pathway|activation of MAP kinase activity by adrenergic receptor signaling pathway The series of molecular signals generated as a consequence of an adrenergic receptor binding to its physiological ligand, followed by the activation of a MAP kinase. UBERON:0002124 medulla of thymus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002124 medulla of thymus gland|thymus gland medulla|thymus medulla Medullary portion of thymus. The reticulum is coarser than in the cortex, the lymphoid cells are relatively fewer in number, and there are found peculiar nest-like bodies, the concentric corpuscles of Hassall. These concentric corpuscles are composed of a central mass, consisting of one or more granular cells, and of a capsule formed of epithelioid cells. They are the remains of the epithelial tubes, which grow out from the third branchial pouches of the embryo to form the thymus. Each follicle is surrounded by a vascular plexus, from which vessels pass into the interior, and radiate from the periphery toward the center, forming a second zone just within the margin of the medullary portion. In the center of the medullary portion there are very few vessels, and they are of minute size. GO:0071882 phospholipase C-activating adrenergic receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071882 adrenergic receptor, phospholipase C activating pathway|activation of phospholipase C activity by adrenergic receptor signalling pathway|activation of phospholipase C activity by adrenergic receptor signaling pathway The series of molecular signals generated as a consequence of an adrenergic receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG). GO:0140061 5-hydroxymethylcytosine dioxygenase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140061 5hmC dioxygenase Catalysis of the reaction: 5-hydroxymethylcytosine + 2-oxoglutarate + O2 = 5-formylcytosine + succinate + CO2. UBERON:0002123 cortex of thymus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002123 thymus cortex|thymic cortex the outer part of a thymus lobule that surrounds the medulla and is composed of closely packed lymphocytes GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071881 adrenergic receptor, adenylyl cyclase inhibiting pathway|inhibition of adenylate cyclase activity by adrenergic receptor signaling pathway|inhibition of adenylate cyclase activity by adrenergic receptor signalling pathway|adrenergic receptor, adenylate cyclase inhibiting pathway The series of molecular signals generated as a consequence of an adrenergic receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP). GO:0140060 axon arborization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140060 The process in which the terminal anatomical structures of an axon are generated and organized into branches of specialised projections, or boutons. An axon is the long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminal branches. GO:1900767 fonsecin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900767 fonsecin metabolism The chemical reactions and pathways involving fonsecin. UBERON:0002108 small intestine biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002108 intestinum tenue|anterior intestine|small bowel|small intestine|mid intestine Subdivision of digestive tract that connects the stomach to the large intestine and is where much of the digestion and absorption of food takes place (with the exception of ruminants). The mammalian small intestine is long and coiled and can be differentiated histologically into: duodenum, jejunem, ileum[WP,cjm,Kardong]. GO:1900766 emericellin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900766 emericellin synthesis|Variecoxanthone B synthesis|emericellin formation|Variecoxanthone B formation|Variecoxanthone B biosynthesis|Variecoxanthone B biosynthetic process|emericellin anabolism|Variecoxanthone B anabolism|emericellin biosynthesis The chemical reactions and pathways resulting in the formation of emericellin. UBERON:0002107 liver biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002107 jecur|iecur An exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes[GO]. GO:1900769 fonsecin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900769 fonsecin anabolism|fonsecin synthesis|fonsecin formation|fonsecin biosynthesis The chemical reactions and pathways resulting in the formation of fonsecin. UBERON:0002109 pair of nares biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002109 nostrils|set of nares|nares set|nares|pair of nostrils Pair of nostrils. GO:1900768 fonsecin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900768 fonsecin catabolism|fonsecin degradation|fonsecin breakdown The chemical reactions and pathways resulting in the breakdown of fonsecin. GO:1900763 averantin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900763 averantin biosynthesis|averantin anabolism|averantin synthesis|averantin formation The chemical reactions and pathways resulting in the formation of averantin. GO:1900762 averantin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900762 averantin breakdown|averantin catabolism|averantin degradation The chemical reactions and pathways resulting in the breakdown of averantin. GO:0140059 dendrite arborization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140059 The process in which the anatomical structures of a dendritic tree are generated and organized into dendritic branches. GO:1900765 emericellin catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900765 Variecoxanthone B catabolism|emericellin degradation|Variecoxanthone B degradation|emericellin breakdown|Variecoxanthone B breakdown|Variecoxanthone B catabolic process|emericellin catabolism The chemical reactions and pathways resulting in the breakdown of emericellin. GO:1900764 emericellin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900764 emericellin metabolism|Variecoxanthone B metabolism|Variecoxanthone B metabolic process The chemical reactions and pathways involving emericellin. GO:1900761 averantin metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900761 averantin metabolism The chemical reactions and pathways involving averantin. GO:1900760 negative regulation of sterigmatocystin biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900760 down-regulation of sterigmatocystin anabolism|negative regulation of sterigmatocystin anabolism|inhibition of sterigmatocystin biosynthesis|down-regulation of sterigmatocystin synthesis|negative regulation of sterigmatocystin synthesis|negative regulation of sterigmatocystin formation|down-regulation of sterigmatocystin formation|down regulation of sterigmatocystin biosynthesis|downregulation of sterigmatocystin anabolism|down regulation of sterigmatocystin biosynthetic process|downregulation of sterigmatocystin biosynthesis|down regulation of sterigmatocystin anabolism|downregulation of sterigmatocystin biosynthetic process|downregulation of sterigmatocystin synthesis|downregulation of sterigmatocystin formation|down regulation of sterigmatocystin synthesis|down regulation of sterigmatocystin formation|inhibition of sterigmatocystin anabolism|down-regulation of sterigmatocystin biosynthesis|negative regulation of sterigmatocystin biosynthesis|down-regulation of sterigmatocystin biosynthetic process|inhibition of sterigmatocystin synthesis|inhibition of sterigmatocystin formation|inhibition of sterigmatocystin biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of sterigmatocystin biosynthetic process. GO:0140052 cellular response to oxidised low-density lipoprotein particle stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140052 cellular response to oxidised LDL particle stimulus|cellular response to oxLDL particle stimulus|cellular response to ox-LDL particle stimulus|cellular response to oxidized low-density lipoprotein particle stimulus|cellular response to oxidized LDL particle stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxidized lipoprotein particle stimulus. GO:0140051 positive regulation of endocardial cushion to mesenchymal transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140051 Any process that activates or increases the frequency, rate or extent of endocardial cushion to mesenchymal transition. CHEBI:3795 cobalt-precorrin-8 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_3795 CHEBI:35544 EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35544 GO:0140053 mitochondrial gene expression biolink:BiologicalProcess go-plus goslim_pombe http://purl.obolibrary.org/obo/GO_0140053 The process in which a mitochondrial gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form. GO:0140056 organelle localization by membrane tethering biolink:BiologicalProcess go-plus goslim_pombe http://purl.obolibrary.org/obo/GO_0140056 The process by which an organelle membrane interacts with another membrane via molecular tethers that physically bridge the two membranes and attach them to each other. CHEBI:35545 bipyridine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35545 GO:0140058 neuron projection arborization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140058 branching morphogenesis of a neurite|neurite branching|branching morphogenesis of a neuron projection|neuron projection branching|neurite arborization The process in which the anatomical structures of a neuron projection are generated and organized into branches. A neuron projection is any process extending from a neural cell, such as axons or dendrites. GO:0071879 positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071879 positive regulation of adrenergic receptor signaling pathway|positive regulation of adrenergic receptor signalling pathway Any process that activates or increases the frequency, rate or extent of the adenylate cyclase-activating adrenergic receptor protein signaling pathway. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands. GO:0071878 negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071878 false|negative regulation of adrenergic receptor signalling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor protein signaling pathway activity. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands. GO:0140057 vacuole-mitochondria membrane tethering biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140057 The attachment of a mitochondrial membrane to a vacuolar membrane via molecular tethers that physically bridge their respective membranes and attach them to each other. The tethering may facilitate exchange of metabolites between the organelles. GO:0071877 regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071877 false|regulation of adrenergic receptor signalling pathway Any process that modulates the frequency, rate or extent of an adenylate cyclase-inhibiting adrenergic receptor signaling pathway activity. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands. GO:0071876 obsolete initiation of adrenergic receptor signal transduction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071876 initiation of adrenergic receptor signal transduction OBSOLETE. A process of signal initiation in which epinephrine or norepinephrine causes activation of an adrenergic receptor. UBERON:0002114 duodenum biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002114 upper intestine|proximal intestine The first part of the small intestine. At the junction of the stomach and the duodenum the alimentary canal is inflected. The duodenum first goes anteriorly for a short distance, turns dorsally, and eventually caudally, thus it is a U-shaped structure with two horizontal sections (a ventral and a dorsal one). GO:0071875 adrenergic receptor signaling pathway biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071875 adrenergic receptor signalling pathway|adrenoceptor signaling pathway A series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands. CHEBI:3790 cobalt-precorrin-2 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_3790 GO:0022900 electron transport chain biolink:BiologicalProcess go-plus goslim_pir http://purl.obolibrary.org/obo/GO_0022900 Wikipedia:Electron_transport_chain A process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient. GO:0071874 cellular response to norepinephrine stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071874 cellular response to noradrenaline stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system. UBERON:0002111 artery smooth muscle tissue biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002111 artery smooth muscle|arterial smooth muscle|artery smooth muscle tissue|arterial smooth muscle cell|smooth muscle of artery A portion of smooth muscle tissue that is part of an artery [Automatically generated definition]. GO:0071873 response to norepinephrine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071873 response to norepinephrine stimulus|response to noradrenaline stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system. CHEBI:3792 cobalt-precorrin-4 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_3792 UBERON:0002110 gall bladder biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002110 gallbladder|gall bladder|vesica biliaris|vesica fellea An organ that aids digestion and stores bile produced by the liver[WP]. GO:0071872 cellular response to epinephrine stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071872 cellular response to adrenaline stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system. CHEBI:3791 cobalt-precorrin-3 biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_3791 GO:0071871 response to epinephrine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071871 response to adrenaline stimulus|response to epinephrine stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system. GO:0140050 negative regulation of endocardial cushion to mesenchymal transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140050 Any process that stops, prevents or reduces the frequency, rate or extent of endocardial cushion to mesenchymal transition. UBERON:0002113 kidney biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002113 reniculate kidney A paired organ of the urinary tract which has the production of urine as its primary function. CHEBI:3794 cobalt-precorrin-6A biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_3794 UBERON:0002112 smooth muscle of esophagus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002112 non-striated muscle of gullet|non-striated muscle of esophagus|involuntary muscle of oesophagus|oesophagus smooth muscle|smooth muscle of gullet|oesophagus involuntary muscle|smooth muscle tissue of gullet|esophagus smooth muscle tissue|gullet smooth muscle tissue|gullet non-striated muscle|esophagus non-striated muscle|gullet smooth muscle|esophagus smooth muscle|non-striated muscle of oesophagus|involuntary muscle of esophagus|involuntary muscle of gullet|smooth muscle of oesophagus|esophagus involuntary muscle|smooth muscle tissue of oesophagus|gullet involuntary muscle|oesophagus non-striated muscle|esophageal smooth muscle|oesophagus smooth muscle tissue|smooth muscle tissue of esophagus A portion of smooth muscle tissue that is part of a esophagus [Automatically generated definition]. GO:0071870 cellular response to catecholamine stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071870 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution. GO:0022904 respiratory electron transport chain biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0022904 Wikipedia:Electron_transfer oxidized glutathione reduction|protein-disulfide reduction|6-phosphofructokinase reduction|electron transfer|other pathways of electron transport|dihydrolipoamide reduction|dihydrobiopterin reduction|dihydropteridine reduction|dihydrolipoylprotein reduction A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient. GO:1900778 fumiquinazoline A biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900778 fumiquinazoline A biosynthesis|fumiquinazoline A anabolism|fumiquinazoline A synthesis|fumiquinazoline A formation The chemical reactions and pathways resulting in the formation of fumiquinazoline A. GO:1900777 fumiquinazoline A catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900777 fumiquinazoline A degradation|fumiquinazoline A catabolism|fumiquinazoline A breakdown The chemical reactions and pathways resulting in the breakdown of fumiquinazoline A. GO:1900779 fumiquinazoline C metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900779 fumiquinazoline C metabolism The chemical reactions and pathways involving fumiquinazoline C. GO:1900774 fumiquinazoline catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900774 fumiquinazoline degradation|fumiquinazolines breakdown|fumiquinazoline catabolism|fumiquinazoline breakdown|fumiquinazolines catabolic process|fumiquinazolines catabolism|fumiquinazolines degradation The chemical reactions and pathways resulting in the breakdown of fumiquinazoline. CHEBI:35517 5beta-cholestane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35517 GO:1900773 fumiquinazoline metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900773 fumiquinazolines metabolic process|fumiquinazoline metabolism|fumiquinazolines metabolism The chemical reactions and pathways involving fumiquinazoline. CHEBI:35516 cholestane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35516 CHEBI:35519 cholane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35519 GO:1900776 fumiquinazoline A metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900776 fumiquinazoline A metabolism The chemical reactions and pathways involving fumiquinazoline A. CHEBI:35518 campestane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35518 GO:1900775 fumiquinazoline biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900775 fumiquinazoline biosynthesis|fumiquinazolines anabolism|fumiquinazoline anabolism|fumiquinazolines synthesis|fumiquinazolines biosynthesis|fumiquinazolines biosynthetic process|fumiquinazoline synthesis|fumiquinazolines formation|fumiquinazoline formation The chemical reactions and pathways resulting in the formation of fumiquinazoline. GO:1900770 fumitremorgin B metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900770 Lanosulin metabolic process|fumitremorgin B metabolism|Lanosulin metabolism The chemical reactions and pathways involving fumitremorgin B. GO:1900772 fumitremorgin B biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900772 fumitremorgin B anabolism|fumitremorgin B biosynthesis|Lanosulin biosynthesis|fumitremorgin B synthesis|Lanosulin biosynthetic process|Lanosulin anabolism|fumitremorgin B formation|Lanosulin synthesis|Lanosulin formation The chemical reactions and pathways resulting in the formation of fumitremorgin B. GO:1900771 fumitremorgin B catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900771 fumitremorgin B breakdown|Lanosulin degradation|Lanosulin breakdown|fumitremorgin B catabolism|Lanosulin catabolic process|Lanosulin catabolism|fumitremorgin B degradation The chemical reactions and pathways resulting in the breakdown of fumitremorgin B. GO:0140084 sexual macrocyst formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140084 macrocyst formation|sexual fusion The fusion of haploid amoebae cells with matching mating types to form a larger cell, which ingests additional amoebae and forms a cellulose wall. The resulting macrocyst undergoes recombination and meiosis followed by release of haploid amoebae. An example of this process can be found in Dictyostelium discoideum. CHEBI:35512 ergostane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35512 CHEBI:3766 clozapine biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_3766 CHEBI:35515 5alpha-cholestane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35515 UBERON:0002104 visual system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002104 visual organ system|photosensory system The sensory system subserving the sense of vision. UBERON:0002103 hindlimb biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002103 inferior member|free part of lower limb|membrum inferius|hind limb|pelvic appendage|membrum inferius|lower extremity|lower limb|hindlimb|hind-limb|free lower limb A (free) limb that is connected to a pelvic girdle region. The extent of this structure includes autopod, stylopod and zeugopod regions when present, but excludes the pelvic girdle and its parts. UBERON:0002106 spleen biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002106 lien the organ that functions to filter blood and to store red corpuscles and platelets UBERON:0002105 vestibulo-auditory system biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002105 vestibuloauditory system|auditory system|vestibuloauditory system|auditory/vestibular system|auditory organ system Sensory system responsible for the perception of spatial orientation and auditory stimuli. UBERON:0002100 trunk biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002100 Rumpf|torso|thoracolumbar region|trunk region Organism subdivision which is the part of the body posterior to the cervical region (or head, when cervical region not present) and anterior to the caudal region. Includes the sacrum when present. GO:0140081 glycosylated region protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140081 Interacting selectively and non-covalently with a glycosylated region of a protein. GO:0140080 class III/IV DNA-(apurinic or apyrimidinic site) endonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140080 endonuclease IV|endonuclease III Catalysis of the cleavage of an AP site 3' and 5' of the baseless site, generating a 3'-phosphate and a 5'-OH. UBERON:0002102 forelimb biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002102 pectoral limb|anteriormost limb|upper extremity|fore limb|upper limb|membrum superius|forelimb|foreleg|pectoral flipper|superior member|free upper limb|free part of upper limb A (free) limb that is connected to a pectoral girdle. The extent of this structure includes autopod, stylopod and zeugopod regions when present, but excludes the pectoral girdle and its parts. GO:0140083 protein-DNA unloading ATPase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140083 Catalysis of the reaction: ATP + H2O = ADP + phosphate , this reaction drives the unwinding of the DNA helix and drives the removal of a protein or protein complex from a DNA molecule, by introducing non-canonical DNA structures or generating torque to directly inhibit a protein-DNA binding interaction. UBERON:0002101 limb biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002101 limb sensu Vertebrata|flipper|extremity|extremities|pentadactyl limb|free limb|tetrapod limb A paired appendage that is evolved from a paired fin. The extent of this structure includes autopod, stylopod and zeugopod regions when present, but excludes the girdle and its parts. GO:0140082 SUMO-ubiquitin ligase activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140082 Isoenergetic transfer of SUMO from one protein to an existing ubiquitin chain via the reaction X-ubiquitin + Y-ubiquitin -> Y-ubiquitin-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue. GO:0071891 N-terminal peptidyl-proline dimethylation involved in translation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071891 An N-terminal peptidyl-proline dimethylation process that contributes to translation. GO:0071890 bicarbonate binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0071890 hydrogencarbonate binding Interacting selectively and non-covalently with bicarbonate (CHO3-) ions. GO:1900789 pseurotin A catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900789 pseurotin A breakdown|Pseurotin degradation|Pseurotin breakdown|pseurotin A catabolism|Pseurotin catabolic process|Pseurotin catabolism|pseurotin A degradation The chemical reactions and pathways resulting in the breakdown of pseurotin A. GO:1900788 pseurotin A metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900788 Pseurotin metabolic process|pseurotin A metabolism|Pseurotin metabolism The chemical reactions and pathways involving pseurotin A. GO:1900785 naphtho-gamma-pyrone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900785 naphtho-gamma-pyrone metabolism|naphtho-gamma-pyrones metabolic process|naphtho-gamma-pyrones metabolism The chemical reactions and pathways involving naphtho-gamma-pyrone. GO:1900784 fumiquinazoline F biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900784 fumiquinazoline F anabolism|fumiquinazoline F biosynthesis|fumiquinazoline F synthesis|fumiquinazoline F formation The chemical reactions and pathways resulting in the formation of fumiquinazoline F. GO:1900787 naphtho-gamma-pyrone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900787 naphtho-gamma-pyrone biosynthesis|naphtho-gamma-pyrones anabolism|naphtho-gamma-pyrones synthesis|naphtho-gamma-pyrones formation|naphtho-gamma-pyrone anabolism|naphtho-gamma-pyrones biosynthesis|naphtho-gamma-pyrone synthesis|naphtho-gamma-pyrones biosynthetic process|naphtho-gamma-pyrone formation The chemical reactions and pathways resulting in the formation of naphtho-gamma-pyrone. GO:1900786 naphtho-gamma-pyrone catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900786 naphtho-gamma-pyrones catabolic process|naphtho-gamma-pyrone degradation|naphtho-gamma-pyrone breakdown|naphtho-gamma-pyrones catabolism|naphtho-gamma-pyrones degradation|naphtho-gamma-pyrones breakdown|naphtho-gamma-pyrone catabolism The chemical reactions and pathways resulting in the breakdown of naphtho-gamma-pyrone. GO:1900781 fumiquinazoline C biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900781 fumiquinazoline C biosynthesis|fumiquinazoline C anabolism|fumiquinazoline C synthesis|fumiquinazoline C formation The chemical reactions and pathways resulting in the formation of fumiquinazoline C. GO:1900780 fumiquinazoline C catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900780 fumiquinazoline C degradation|fumiquinazoline C breakdown|fumiquinazoline C catabolism The chemical reactions and pathways resulting in the breakdown of fumiquinazoline C. GO:1900783 fumiquinazoline F catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900783 fumiquinazoline F degradation|fumiquinazoline F breakdown|fumiquinazoline F catabolism The chemical reactions and pathways resulting in the breakdown of fumiquinazoline F. GO:1900782 fumiquinazoline F metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900782 fumiquinazoline F metabolism The chemical reactions and pathways involving fumiquinazoline F. GO:0140074 cardiac endothelial to mesenchymal transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140074 EndMT|EndoMT A transition where a cardiac endothelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. Endocardial cells (specialized endothelial cells that line the heart) undergo EndMT, and give rise to mesenchymal cells necessary for proper heart development. EndMT, specifically generates valve progenitor cells that give rise to the mitral and tricuspid valves. EndMT also contributes to endocardial cushion formation, as well as to generation of cardiac fibroblasts and smooth muscle cells, but not cardiac myocytes. GO:1900790 pseurotin A biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900790 Pseurotin formation|pseurotin A biosynthesis|pseurotin A anabolism|Pseurotin biosynthesis|pseurotin A synthesis|Pseurotin biosynthetic process|Pseurotin anabolism|pseurotin A formation|Pseurotin synthesis The chemical reactions and pathways resulting in the formation of pseurotin A. GO:0140076 negative regulation of lipoprotein transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140076 Any process that stops, prevents or reduces the frequency, rate or extent of lipoprotein transport. CHEBI:35522 beta-adrenergic agonist biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35522 GO:0140075 regulation of lipoprotein transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140075 Any process that controls lipoprotein transport. CHEBI:35524 sympathomimetic agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35524 GO:0140078 class I DNA-(apurinic or apyrimidinic site) endonuclease activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140078 MetaCyc:4.2.99.18-RXN|EC:4.2.99.18 DNA-(apurinic or apyrimidinic site) lyase activity|class I DNA-(apurinic or apyrimidinic site) lyase activity|AP endonuclease class I activity|AP site-DNA 5'-phosphomonoester-lyase activity|DNA-(apurinic or apyrimidinic site) 5'-phosphomonoester-lyase activity Catalysis of the cleavage of an AP site 3' of the baseless site by a beta-lyase mechanism, leaving an unsaturated aldehyde, termed a 3'-(4-hydroxy-5-phospho-2-pentenal) residue, and a 5'-phosphate. GO:0140077 positive regulation of lipoprotein transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140077 Any process that activates or increases the rate or extent of lipoprotein transport. CHEBI:35523 bronchodilator agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35523 CHEBI:35526 hypoglycemic agent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35526 GO:0140079 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0140079 GO:0071899 negative regulation of estrogen receptor binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071899 Any process that stops, prevents, or reduces the frequency, rate or extent of estrogen receptor binding, interacting selectively with an estrogen receptor. GO:0071898 regulation of estrogen receptor binding biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071898 Any process that modulates the frequency, rate or extent of estrogen receptor binding, interacting selectively with a an estrogen receptor. GO:0071897 DNA biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071897 DNA biosynthesis|DNA anabolism|DNA synthesis|DNA formation The cellular DNA metabolic process resulting in the formation of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one. GO:0071896 protein localization to adherens junction biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071896 protein localization in cell-cell adherens junction|protein localisation to adherens junction|protein localisation in cell-cell adherens junction|protein localization to cell-cell adherens junction|protein localization in adherens junction|protein localisation to cell-cell adherens junction|protein localisation in adherens junction Any process in which a protein is transported to, and/or maintained at the adherens junction. GO:0071895 odontoblast differentiation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071895 The process in which a relatively unspecialized cell of neural crest origin acquires the specialized features of an odontoblast, a cell on the outer surface of the dental pulp whose biological function is the creation of dentin. GO:0071894 histone H2B conserved C-terminal lysine ubiquitination biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071894 budding yeast H2B K123 ubiquitination|mammalian H2B K120 ubiquitination|fission yeast H2B K119 ubiquitination A histone ubiquitination process in which a ubiquitin monomer is added to a conserved lysine residue in the C-terminus of histone H2B. The conserved lysine residue is K119 in fission yeast, K123 in budding yeast, or K120 in mammals. GO:0071893 BMP signaling pathway involved in nephric duct formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071893 BMP signalling pathway involved in nephric duct formation A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to nephric duct formation. GO:0071892 thrombocyte activation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0071892 blood coagulation, thrombocyte activation A cell activation process that occurs in thrombocytes and consists of a series of progressive, overlapping events including shape change, adhesiveness, and aggregation, which, when carried through to completion, lead to the formation of a stable hemostatic plug. Thrombocytes are nucleated cells found in non-mammalian vertebrates and are involved in hemostasis. They are the functional equivalent of the non-nucleated platelets found in mammals. GO:1900799 cordyol C biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900799 cordyol C anabolism|cordyol C biosynthesis|cordyol C synthesis|cordyol C formation The chemical reactions and pathways resulting in the formation of cordyol C. GO:0140027 establishment of contractile vacuole localization biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140027 The directed movement of the contractile vacuole to a specific location. GO:1900796 terrequinone A biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900796 terrequinone A biosynthesis|terrequinone A anabolism|terrequinone A synthesis|terrequinone A formation The chemical reactions and pathways resulting in the formation of terrequinone A. GO:0140026 contractile vacuole dissociation from plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140026 contractile vacuole detethering from plasma membrane The dissociation of the contractile vacuole after discharge, from the plasma membrane. This interaction is mediated by detethering factors that initiate the process of tubulation and fragmentation of the empty contractile vacuole bladder, which is then reincorporated into the CV network. GO:1900795 terrequinone A catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900795 terrequinone A degradation|terrequinone A breakdown|terrequinone A catabolism The chemical reactions and pathways resulting in the breakdown of terrequinone A. GO:1900798 cordyol C catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900798 cordyol C catabolism|cordyol C degradation|cordyol C breakdown The chemical reactions and pathways resulting in the breakdown of cordyol C. GO:0140029 exocytic process biolink:BiologicalProcess go-plus gocheck_do_not_annotate http://purl.obolibrary.org/obo/GO_0140029 The cellular processes that contribute to exocytosis. GO:0140028 pore formation during contractile vacuole discharge biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140028 The formation of a transient pore in the plasma membrane and the attached contractile vacuolar membrane, to release water from the cell. This process does not involve fusion of the two membranes. GO:1900797 cordyol C metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900797 cordyol C metabolism The chemical reactions and pathways involving cordyol C. GO:1900792 shamixanthone catabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900792 shamixanthone breakdown|shamixanthone degradation|shamixanthone catabolism The chemical reactions and pathways resulting in the breakdown of shamixanthone. GO:1900791 shamixanthone metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900791 shamixanthone metabolism The chemical reactions and pathways involving shamixanthone. GO:1900794 terrequinone A metabolic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900794 terrequinone A metabolism The chemical reactions and pathways involving terrequinone A. GO:1900793 shamixanthone biosynthetic process biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_1900793 shamixanthone biosynthesis|shamixanthone anabolism|shamixanthone synthesis|shamixanthone formation The chemical reactions and pathways resulting in the formation of shamixanthone. GO:0140021 mitochondrial ADP transmembrane transport biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140021 The process in which ADP is transported across a mitochondrial membrane, into or out of the mitochondrion. UBERON:0002164 tectobulbar tract biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002164 tecto-bulbar tract|tractus tectobulbaris A long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the optic tectum towards target cells in the premotor reticulospinal system in the hindbrain. GO:0140020 DNA methyltransferase complex biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140020 A protein complex that possesses DNA methyltransferase activity. GO:0140023 tRNA adenosine deamination to inosine biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140023 A-to-I tRNA editing The removal of an amine group from an adenosine to produce inosine within a tRNA molecule. GO:0140022 cnida biolink:CellularComponent go-plus http://purl.obolibrary.org/obo/GO_0140022 cnidae (plural) A giant secretory organelle that comprises a bulb-shape capsule containing a coiled hollow tubule structure attached to it. A cnida defines the phylum Cnidaria. GO:0140025 contractile vacuole tethering involved in discharge biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140025 contractile vacuole tethering to plasma membrane The initial, indirect interaction between a contractile vacuole membrane and a site of discharge in the plasma membrane. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to docking and fusion. GO:0140024 plus-end-directed endosome transport along mitotic spindle midzone microtubule biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140024 The directed movement of an endosome towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of an endosome to a microtubule, and ends when the endosome reaches its final destination. UBERON:0002169 alveolar sac biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002169 sacculus alveolaris|air sac|pulmonary alveolar sac The small terminal dilation of the alveolar ducts around which the alveoli form pocket-like clusters UBERON:0002166 endocardium of atrium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002166 endocardium of atrium of heart|atrial endocardium|Cardiac atria endocardium|atrium endocardial tissue|endocardium of cardiac atrium|endocardium of Cardiac atria|cardiac atrium endocardium|endocardium of heart atrium|atrium endocardium|heart atrium endocardium|atrium of heart endocardium Endocardium that is part of the atrium. UBERON:0002165 endocardium biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002165 endocardial tissue|heart endocardial tissue|heart endocardium|endocardial lining The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers[GO]. UBERON:0002168 left lung biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002168 Lung which consists of the left upper lobe and left lower lobe.[FMA] UBERON:0002167 right lung biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002167 Lung which consists of the right upper lobe, middle lobe and right lower lobe.[FMA] CHEBI:35506 alkaloid fundamental parent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35506 GO:0140016 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0140016 CHEBI:35505 hydrate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35505 CHEBI:35508 steroid fundamental parent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35508 GO:0140018 regulation of cytoplasmic translational fidelity biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140018 Any process that modulates the ability of the cytoplasmic translational apparatus to interpret the genetic code. CHEBI:11515 2-amino-5-formylamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_11515 CHEBI:35507 natural product fundamental parent biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35507 CHEBI:35509 androstane biolink:ChemicalSubstance go-plus chebi_ph7_3 http://purl.obolibrary.org/obo/CHEBI_35509 UBERON:0002153 fastigial nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002153 nucleus fastigii|fastigial cerebellar nucleus|fasciculosus thalamic nucleus|nucleus fastigii cerebelli|medial cerebellar nucleus|medial (fastigial) nucleus|nucleus (motorius) tecti cerebelli|medial nucleus of cerebellum|nucleus fastigiatus|nucleus fastigius cerebelli|roof nucleus-1|nucleus fastigii the most medial of the cerebellar nuclei; it receives its afferent input from Purkinje cells of the flocculonodular lobe and the vermis, and most of its efferent connections travel via the inferior cerebellar peduncle to the vestibular nuclei and to the medullary reticular formation GO:0140010 D-aspartate transmembrane transporter activity biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140010 Enables the transfer of D-aspartate from one side of a membrane to the other. CHEBI:35500 1,4-benzodiazepinone biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35500 GO:0140014 mitotic nuclear division biolink:BiologicalProcess go-plus goslim_generic|goslim_chembl http://purl.obolibrary.org/obo/GO_0140014 mitosis A mitotic cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell. CHEBI:35504 addition compound biolink:ChemicalSubstance go-plus http://purl.obolibrary.org/obo/CHEBI_35504 GO:0140013 meiotic nuclear division biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140013 meiosis One of the two nuclear divisions that occur as part of the meiotic cell cycle. UBERON:0002154 lateral reticular nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002154 lateral reticular nucleus (medulla)|lateral reticular nuclei|nucleus reticularis lateralis medullae oblongatae A nucleus of the lateral medullary nuclear complex. GO:0140049 regulation of endocardial cushion to mesenchymal transition biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140049 Any process that modulates the frequency, rate or extent of endocardial cushion to mesenchymal transition. GO:0140048 manganese ion export across plasma membrane biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140048 manganese ion export from cell The directed movement of manganese ions from inside of a cell, across the plasma membrane and into the extracellular region. GO:0140041 cellular detoxification of methylglyoxal biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140041 Any process carried out at the cellular level that reduces or removes the toxicity of methylglyoxal. GO:0140040 mitochondrial polycistronic RNA processing biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140040 The conversion of polycistronic RNA transcribed from a mitochondrial genome into mono- or bi-cistronic RNAs. GO:0140043 lipid droplet localization to prospore membrane leading edge biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140043 adiposome localization to forespore membrane leading edge|lipid particle localization to forespore membrane leading edge|adiposome localization to FSM membrane leading edge|lipid body localization to forespore membrane leading edge|lipid particle localization to FSM membrane leading edge|lipid body localization to FSM membrane leading edge|adiposome localization to ascospore-type prospore membrane leading edge|lipid particle localization to ascospore-type prospore membrane leading edge|lipid body localization to ascospore-type prospore membrane leading edge Any process in which a lipid droplet is transported to, or maintained to the prospore membrane leading edge. UBERON:0002142 pedunculopontine tegmental nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002142 nucleus pedunculopontinus|peduncular pontine nucleus|pedunculopontine nucleus|PPTg|nucleus tegmenti pedunculopontinus The pedunculopontine nucleus (PPN) (or pedunculopontine tegmental nucleus, PPTN) is located in the brainstem, caudal to the substantia nigra and adjacent to the superior cerebellar peduncle. It is composed by a wide variety of neurochemical cell types, including cholinergic, glutamatergic and GABAergic cells. In the classical sense, the PPN is considered to be one of the main components of the reticular activating system. [WP,unvetted]. GO:0140042 lipid droplet formation biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140042 lipid body formation|adiposome formation|lipid particle formation A process that results in the assembly, arrangement of constituent parts of a lipid droplet. GO:0140045 biolink:OntologyClass go-plus http://purl.obolibrary.org/obo/GO_0140045 UBERON:0002148 locus ceruleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002148 loci coeruleus|nucleus caeruleus|substantia ferruginea|locus coeruleus|nucleus pigmentosus pontis|blue nucleus|locus cinereus|nucleus loci caerulei|locus coeruleus (Vicq d'Azyr)|nucleus of locus caeruleus|caerulean nucleus|locus coeruleu|locus caeruleus The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic[GO]. Bluish region in the superior angle of the fourth ventricle floor, corresponding to melanin-like pigmented nerve cells which lie lateral to the ponto-mesencephalic central gray (griseum centrale). It is also known as nucleus pigmentosus pontis[GAID]. UBERON:0002149 superior salivatory nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002149 nucleus salivatorius superior|nucleus salivatorius rostralis|nucleus salivarius superior|nucleus salivatorius cranialis|superior salivary nucleus Nucleus containing parasympathetic neurons giving rise to the parasympathetic division of the facial nerve, innervating the salivary glands (Brodal, Neurological Anatomy, 3rd ed., 1981, pg 703). UBERON:0002146 pulmonary valve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002146 pulmonic valve|valva trunci pulmonalis the semilunar valve of the heart that lies between the right ventricle and the pulmonary artery. UBERON:0002129 cerebellar cortex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002129 cortex of cerebellar hemisphere|cortex cerebellaris|cortex cerebelli The superficial gray matter of the cerebellum. It consists of three main layers, the molecular layer, the Purkinje cell layer and the granule cell layer. GO:0140037 sumo-dependent protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140037 Interacting selectively and non-covalently with a protein upon sumoylation of the target protein. GO:0140039 cell-cell adhesion in response to extracellular stimulus biolink:BiologicalProcess go-plus http://purl.obolibrary.org/obo/GO_0140039 The attachment of one cell to another cell via adhesion molecules as a result of an extracellular stimulus. GO:0140030 modification-dependent protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140030 modified protein binding Interacting selectively and non-covalently with a protein upon post-translation modification of the target protein. GO:0140032 glycosylation-dependent protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140032 Interacting selectively and non-covalently with a protein upon glycosylation of the target protein. UBERON:0002130 cerebellar nuclear complex biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002130 intrinsic nuclei of cerebellum|roof nuclei-2|nuclei cerebelli|nuclei cerebelli|central nuclei|nuclei cerebellares|nuclei cerebellaris|deep cerebellar nuclei|deep cerebellar nuclear complex|intracerebellar nuclei|cerebellar nuclei The gray matter nuclei located in the center of the cerebellum, embedded in the white matter, which receive inhibitory (GABAergic) inputs from Purkinje cells in the cerebellar cortex and excitatory (glutamatergic) inputs from mossy fiber pathways; all output fibers of the cerebellum originate from the these nuclei[MP] GO:0140031 phosphorylation-dependent protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140031 Interacting selectively and non-covalently with a protein upon phosphorylation of the target protein. GO:0140034 methylation-dependent protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140034 Interacting selectively and non-covalently with a protein upon methylation of the target protein. GO:0140033 acetylation-dependent protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140033 Interacting selectively and non-covalently with a protein upon acetylation of the target protein. GO:0140036 ubiquitin-dependent protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140036 Interacting selectively and non-covalently with a protein upon ubiquitination of the target protein. GO:0140035 ubiquitination-like modification-dependent protein binding biolink:MolecularActivity go-plus http://purl.obolibrary.org/obo/GO_0140035 Interacting selectively and non-covalently with a protein upon modification by a ubiquitin-like protein of the target protein. UBERON:0002137 aortic valve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002137 valva aortae Cardiac valve which has as its parts the anterior, right posterior and left posterior cusps, attached to the fibrous ring of aortic valve.[FMA] UBERON:0002133 atrioventricular valve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002133 AV valve|atrio-ventricular valve A cardial valve in the atrioventricular region that separates the atrium from the ventricle and prevent backflow from the ventricles into the atria during systole. UBERON:0002132 dentate nucleus biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002132 lateral cerebellar nucleus|lateral nucleus of cerebellum|nucleus lateralis cerebelli|nucleus dentatus|dentatothalamocortical fibers|dentate nucleus|dentate nucleus (Vicq d'Azyr)|dentate cerebellar nucleus|nucleus dentatus cerebelli the largest and most lateral of the deep cerebellum nuclei; it receives axons of Purkinje cells in the lateral cerebellar hemisphere (neocerebellum) and receives its afferents from the premotor cortex and the supplementary motor cortex through the pontocerebellar system, and its efferents project through the superior cerebellar peduncle and is a major source of its fibers UBERON:0002135 mitral valve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002135 valva atrioventricularis sinistra|left atrioventricular valve|valva mitralis|bicuspid valve An atrioventricular valve that is part of the outflow part of the left atrium. UBERON:0002134 tricuspid valve biolink:AnatomicalEntity go-plus http://purl.obolibrary.org/obo/UBERON_0002134 valvula tricuspidalis|valva atrioventricularis dextra|right atrioventricular valve An atrioventricular valve that is part of the outflow part of the right atrium. PATO:0002236 CARO:0001001 CL:0000881 PATO:0002299 UBERON:0002027 PATO:0002462 CL:0000353 PATO:0000963 UBERON:0002025 PATO:0000964 PATO:0001171 PATO:0001987 MOD:00696 CL:0000508 UBERON:0002227 ENVO:00002030 PATO:0001185 PATO:0001190 PATO:0000407 UBERON:0008925 UBERON:0008926 PATO:0002519 CL:0007002 PATO:0000998 UBERON:0010005 CL:0007001 PR:000015557 CL:0000335 CL:0000118 CHEBI:167049 CL:0000555 PATO:0001735 UBERON:0002313 CL:0002082 CL:0002083 PATO:0001544 CL:1000309 PATO:0001297 UBERON:0005751 CHEBI:3311 NCBITaxon:7586 CL:0000354 CL:0002173 CL:0002220 CL:1000303 PR:000007499 PR:000014841 PATO:0001547 CL:0000313 PATO:0010001 CL:0000352 PATO:0002422 PATO:0000610 CL:1000306 CL:0002073 CL:0002074 IDO:0000404 PATO:0002255 PATO:0002507 PR:000028527 PATO:0002468 BFO:0000024 ENVO:01000048 PATO:0000608 NBO:0000347 ENVO:00000446 ENVO:00000447 CHEBI:22868 owl:Thing BTO:0001117 PATO:0002444 NCBITaxon:9989 CL:0002199 UBERON:0005376 CL:0000652 CL:0002166 CL:0002258 OBI:0100026 PATO:0002045 CL:0005009 CL:0002312 CL:0002095 PR:000007636 PATO:0001748 CL:0002294 CL:0000432 CL:0000347 CL:0000446 CL:0000853 PATO:0002198 UBERON:0002512 CL:0000745 PATO:0001548 ENVO:00000568 NBO:0000412 CL:0002064 NBO:0000073 PATO:0001993 CHEBI:36277 CL:0000642 CL:0000214 PATO:0001187 PATO:0001690